bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostics for Genetically Inherited Disorders: From Cytogenetics to Genomics Technologies- A Review
Authors: Banu Meraj , Pathan Akbar Ali Khan , Chaitanya K.V.
Published: July 2023

The frequent occurrence of chromosomal abnormalities in humans is one of the main factors responsible for the birth of children with disabilities. More than 7.6 million infants per year are diagnosed with severe genetic abnormalities. An increase in genetic abnormalities among children may be attributed to women suffering from hormonal disorders. Genetic malformations can either be hereditary or spontaneous due to the exposure of germinal cells to toxins and mutagens or even oxidative stress. Most genetic disorders lack proper treatment. However, proper counseling, therapy, and medication can minimize its impact. Early diagnosis of abnormalities in the fetus will benefit the parents in options assessment. Fetal chromosomal analysis is the best option for an appropriate genetic disorder diagnosis. The latest and emerging technologies involved in detecting chromosomal abnormalities at the prenatal stage are discussed in this review. Significant developments in prenatal diagnostics and the best globally available economical options were also discussed.
Immunohistochemical and Ultrastructural Evaluation of Spermatogenic Alteration by P53 under the Influence of Bisphenol-A
Authors: Srivastava Seema , Sharma Raksha , Sharma Manish Kumar
Published: July 2023

The p53 gene is a tumor suppressor gene and, thus, plays an important role in cell cycle, cell senescence, DNA repair, and cell death. Since testicular tissues go through a continuous and complex process of spermatogenesis, p53 is likely to play a significant role in the regulation of germ cell proliferation and spermiogenesis. In the present study, the specific localization of p53 in testicular tissues was determined by comparing it with BPA induced toxicity. Four groups containing 10 albino rats each were designated as Group I: Control, Group II: 10 mg/kg BPA, Group III: 50 mg/kg BPA, and Group IV: 100 mg/kg BPA. Daily administration of BPA was carried out through oral gavage for 6 weeks by dissolving the assigned weight of BPA in olive oil. Testicular tissues were investigated for expression of p53 by immunohistochemistry, and testicular sperms were examined under a scanning electron microscope. Results showed that p53 was exclusively expressed in the spermatogonia of animals exposed to 10 mg/kg BPA. The highest expression of p53 was present in animals exposed to 50 mg/kg BPA; besides spermatogonia, spermatocytes and spermatids also indicated positive expression. However, relatively lower expression was evident in animals exposed to 100 mg/kg BPA, as most cellular architecture was already distorted significantly, and germ cells appeared to have fallen into the lumen of seminiferous tubules. The ultrastructure of testicular sperm indicated specific damage to the perforatorium, plasma membrane, and connecting pieces around the neck, and tail. Damages occurring in the head cap segment of the perforatorium indicated an alteration during spermiogenesis. In conclusion, it is highly likely that a BPA induced alteration in the expression of p53 may have affected spermiogenesis through spermatogenesis.
Anti-Urolithiatic and Nephroprotective Activity of Quercetin and Betulin in Conjunction with a Bio Enhancer – An in Vivo Study
Authors: Nagula Shilpika , Subhashini N. J. P. , Bhikshapathi D. V. R. N. , Mamatha Palanati , Rao. P Sailaja
Published: July 2023

Background: In the Indian Traditional system of Medicine, the herbal drug Aerva lanata was widely used in the management of urolithiasis. In the present study, a bioenhancer was used to evaluate the potential of constituents quercetin and betulin isolated from the plant A.lanata. Objective: In the present study, the isolated compounds quercetin and betulin from the plant A.lanata were screened for in vivo anti-urolithiasis and nephroprotective activities. Methodology: In the Wistar albino rats, urolithiasis was induced by ethylene glycol (0.75% v/v) to study the anti-urolithiatic activity. The animals were divided into seven groups of 6 animals in each group (n=6). The study period was for 28-day treatment with quercetin and betulin in combination with piperine as bio enhancers in nephrolithiasis induced rats. The Nephroprotective effect was also investigated in Gentamicin induced nephrotoxicity animal model. Cystone (750 mg/kg) was used as a standard. Biochemical parameters such as blood urea nitrogen (BUN), uric acid, and creatinine in the serum were determined. Renal calculi were determined in kidney homogenate and histopathology was also examined. Results: With the test drug treatment, animals showed increased urine volume signiﬁcantly, also the renal tissue exhibited a reduction in the calculi formation. In the disease control animals, there was an increase in the serum BUN, uric acid, and creatinine significantly. Serum analysis revealed a signiﬁcant reduction (*p<0.001) in the levels of BUN, uric acid, and creatinine in treated rats. Histopathological studies disclosed an improvement in the anatomical aspect of renal tissue. Conclusion: It was concluded that quercetin and betulin exhibited anti-urolithiatic effect by a reduction in the formation of calculi. The current study provided a rationale for the combination of piperine, quercitin, and betulin.
10×10  Gbs directly modulated DFB laser array based on the REC technique
Authors: Yuan Wei , Zhao Jie , Wang Yaguang , Sun Zhenxing , Xiao Rulei , Chen Xiangfei
Published: July 2023

We proposed and experimentally demonstrated a directly modulated distributed feedback (DFB) laser array with a transmission rate of 100 Gbps (10channels×10Gbps). The grating design is based on the reconstruction equivalent chirp (REC) technique, which enables precise control of the channel wavelength spacing to 100 GHz, as specified in the ITU-DWDM standard. DFB laser arrays incorporating the REC technique demonstrate excellent consistency performance, with a side-mode suppression ratio exceeding 48 dB, threshold current of approximately 20 mA, and modulation bandwidth of greater than 13 GHz at a bias current of 100 mA. We evaluated the laser’s performance by loading a 10 Gbps nonreturn-to-zero signal onto the laser using direct modulation and transmitting it over a 10 km single-mode fiber. Based on our experimental results, the proposed DFB laser array is promising to be utilized in the next generation of low-cost, 100 Gbps DWDM communication systems.
Are camera, projector, and camera–projector calibrations different?
Authors: Juarez-Salazar Rigoberto , Esquivel-Hernandez Sofia , Diaz-Ramirez Victor H.
Published: July 2023

Structured light projection systems have become a referent in three-dimensional optical metrology. Calibration of the cameras and projectors of these systems is one of the most critical procedures to achieve high-accuracy measurements. However, the calibration process requires some clarifications for adequate experimental implementation. For instance, it is typically assumed that the calibration of a camera–projector pair differs from calibrating a camera, and the calibration of a projector is possible only with an attached auxiliary camera. This paper presents a unified methodology for camera, projector, and camera–projector calibrations. Experimental results are discussed, providing practical insights into how structured light systems are calibrated. The MATLAB code and data employed in this study are available.
Does age matter?—Efficiency of mechanical food break down in Tupaia belangeri at different ages
Authors: Schwermann Achim H. , Schultz Julia A. , Fuchs Eberhard , Leha Andreas , Hummel Jürgen , Kullmer Ottmar , Steuer Patrick , Martin Thomas
Published: July 2023

The relationship of food comminution and individual age in Tupaia belangeri is investigated. It is hypothesized that with increasing age the performance of the molar dentition decreases due to progressive tooth wear. While this relationship is well-documented for herbivores, age-related test series are largely lacking for insectivorous mammals. 15 individuals of Tupaia belangeri were fed exclusively with mealworms, and their faeces were analyzed for the number and size of chitin particles. The exoskeleton of a mealworm is resistant to digestive fluids in the gastrointestinal tract, and the size of individual chitin particles indicates the effectiveness of mechanical comminution that occurs in the oral cavity during mastication. It is hypothesized that a more precise occlusion of the dentition results in smaller particle size. Although individuals of all ages (juvenile, adult, and senile) were able to effectively process mealworms with their dentition prior to digestion, a larger area of very large chitin particles (98% quantile of all particles in senile animals as compared to in the same quantile in adults) in the feces of senile animals was detected. Even though the particle size of indigestible material is irrelevant for the digestive process, these findings either document somatic senescence in the functionality of the teeth, or alternatively a change in chewing behaviour with age.
The global convergence properties of an adaptive QP-free method without a penalty function or a filter for minimax optimization
Authors: Su Ke , Liu Shaohua , Lu Wei
Published: July 2023

In this paper, we proposed an adaptive QP-free method without a penalty function or a filter for minimax optimization. In each iteration, solved two linear systems of equations constructed from Lagrange multipliers and KKT-conditioned NCP functions. Based on the work set, the computational scale is further reduced. Instead of the filter structure, we adopt a nonmonotonic equilibrium mechanism with an adaptive parameter adjusted according to the result of each iteration. Feasibility of the algorithm are given, and the convergence under some assumptions is demonstrated. Numerical results and practical application are reported at the end.
Prevalence and associated factors of pediatric hypertension in Jazan region, south of the Kingdom of Saudi Arabia. A pilot cross-sectional study
Authors: El-Setouhy Maged , Safhi Abdulrahman M. , Dallak Musab Y. , Ayoub Ahmed Y. , Suwaid Osama A. H. , Moafa Ahmed K. , Al-ahmed Alhassan M. , Zaino Mohammad , Al Sayed Ahmed
Published: July 2023

Hypertension (HTN) is a primary global health concern. Moreover, according to the 2010 Global Burden of Disease, hypertension accounted for roughly a quarter of cardiovascular disease fatalities and 1.9 percent of all deaths in Saudi Arabia in 2010. Also, hypertension is a significant risk factor for cardiovascular disease, morbidity, and mortality. However, assessing blood pressure (BP) and preventing hypertension among children and adolescents has become a global priority. This study aims to determine the prevalence of hypertension among children in the Jazan region of Saudi Arabia. Also, to determine the common risk factors associated with pediatric hypertension. We conducted this cross-sectional study among boys and girls aged 6–14 years visiting Al-Rashid Mall, one of the two main malls in Jazan city, the capital of Jazan region, Saudi Arabia, between November 2021 and January 2022. We included children willing to participate in the study after obtaining their parents’ consent and children’s assent. We used a standardized questionnaire to interview the parents to collect the children’s data. We also measured the children’s resting BP. Then we classified the measurements according to the updated International Pediatric Hypertension Association (IPHA) chart. We also measured the height and weight of the children and calculated their BMI. We used SPSS version 25 for the data entry and analysis. Our results showed that the prevalence of hypertension and prehypertension was insignificantly higher in females (11.84% and 12.65%) compared to males (11.52% and 11.52%), respectively. Our participants’ main associated factors with prehypertension and hypertension were overweight, obesity, and family income. Pediatric hypertension and prehypertension were highly prevalent in Jazan region. Therefore, being overweight and obese should be considered risk factors for pediatric hypertension. Our study emphasizes the need for early intervention to prevent pediatric HTN, particularly among overweight and obese children.
Differentiated service delivery models for antiretroviral treatment refills in Northern Nigeria: Experiences of people living with HIV and health care providers–A qualitative study
Authors: Semo Bazghina-werq , Ezeokafor Nnenna , Adeyemi Sylvester , Kpamor Zipporah , Mugo Cyrus
Published: July 2023

Differentiated service delivery (DSD) and multi-month dispensing (MMD) of antiretroviral therapy (ART) have improved treatment adherence and viral suppression among people living with HIV (PLHIV), and service delivery efficiency. We assessed the experiences of PLHIV and providers with DSD and MMD in Northern Nigeria. We conducted in-depth interviews (IDI) with 40 PLHIV and 6 focus group discussions (FGD) with 39 health care providers across 5 states, exploring their experiences with 6 DSD models. Qualitative data were analyzed using NVivo®1.6.1. Most PLHIV and providers found the models acceptable and expressed satisfaction with service delivery. The DSD model preference of PLHIV was influenced by convenience, stigma, trust, and cost of care. Both PLHIV and providers indicated improvements in adherence and viral suppression; they also raised concerns about quality of care within community-based models. PLHIV and provider experiences suggest that DSD and MMD have the potential to improve patient retention rates and service delivery efficiency.
Development and validation of an environmental DNA assay to detect federally threatened groundwater salamanders in central Texas
Authors: Adcock Zachary C. , Adcock Michelle E. , Forstner Michael R. J.
Published: July 2023

The molecular detection of DNA fragments that are shed into the environment (eDNA) has become an increasingly applied tool used to inventory biological communities and to perform targeted species surveys. This method is particularly useful in habitats where it is difficult or not practical to visually detect or trap the target organisms. Central Texas Eurycea salamanders inhabit both surface and subterranean aquatic environments. Subterranean surveys are challenging or infeasible, and the detection of salamander eDNA in water samples is an appealing survey technique for these situations. Here, we develop and validate an eDNA assay using quantitative PCR for E. chisholmensis, E. naufragia, and E. tonkawae. These three species are federally threatened and constitute the Septentriomolge clade that occurs in the northern segment of the Edwards Aquifer. First, we validated the specificity of the assay in silico and with DNA extracted from tissue samples of both target Septentriomolge and non-target amphibians that overlap in distribution. Then, we evaluated the sensitivity of the assay in two controls, one with salamander-positive water and one at field sites known to be occupied by Septentriomolge. For the salamander-positive control, the estimated probability of eDNA occurrence (ψ) was 0.981 (SE = 0.019), and the estimated probability of detecting eDNA in a qPCR replicate (p) was 0.981 (SE = 0.011). For the field control, the estimated probability of eDNA occurring at a site (ψ) was 0.938 (95% CRI: 0.714–0.998). The estimated probability of collecting eDNA in a water sample (θ) was positively correlated with salamander relative density and ranged from 0.371 (95% CRI: 0.201–0.561) to 0.999 (95% CRI: 0.850– > 0.999) among sampled sites. Therefore, sites with low salamander density require more water samples for eDNA evaluation, and we determined that our site with the lowest estimated θ would require seven water samples for the cumulative collection probability to exceed 0.95. The estimated probability of detecting eDNA in a qPCR replicate (p) was 0.882 (95% CRI: 0.807–0.936), and our assay required two qPCR replicates for the cumulative detection probability to exceed 0.95. In complementary visual encounter surveys, the estimated probability of salamanders occurring at a known-occupied site was 0.905 (SE = 0.096), and the estimated probability of detecting salamanders in a visual encounter survey was 0.925 (SE = 0.052). We additionally discuss future research needed to refine this method and understand its limitations before practical application and incorporation into formal survey protocols for these taxa.
Intellectual conflicts of interest among cardiology and pulmonology clinical practice guidelines
Authors: Brems J. Henry , Wagner Taylor , Diamant Julia , Davis Andrea E. , Clayton Ellen Wright
Published: July 2023

Background

Intellectual conflicts of interest (COI), like financial COI, may threaten the validity and trustworthiness of clinical practice guidelines (CPGs). However, comparatively little is known about intellectual COI in CPGs. This study sought to estimate the prevalence of intellectual COI and corresponding management strategies among cardiology and pulmonology CPGs.

Methods

We conducted a retrospective document review of CPGs published by cardiology or pulmonology professional societies from the United States, Canada, or Europe from 2018 to 2019 available via the Emergency Care Research Institute, Guidelines International Network, or Medscape databases. We assessed the percentage of authors with an intellectual COI, defined as i) authorship on a study reviewed by the CPG, ii) authorship of a prior editorial related to a CPG recommendation, or iii) authorship of a prior related CPG. Management strategies assessed included use of GRADE methodology, inclusion of a methodologist, and recusals due to intellectual COI. Outcomes were assessed overall and compared between cardiology and pulmonology CPGs.

Results

Among the 39 CPGs identified (14 cardiology, 25 pulmonology), there were a total of 737 authors, of whom 473 (64%) had at least one intellectual COI. Among all CPGs, a median of 67% (Interquartile Range 50%-76%) of authors had at least one intellectual COI, and COI was more prevalent among cardiology compared with pulmonology CPGs (84% vs 57%, p<0.001). There was variable use of management strategies among the CPGs, including use of GRADE methodology (64% of CPGs), inclusion of a methodologist (49%), and recusals due to intellectual COI (0%).

Conclusion

Intellectual conflicts of interest appear to be highly prevalent and under-reported among cardiology and pulmonology CPGs, which may threaten their validity. Greater attention to and improved management of intellectual COI by CPG-producing organizations is needed.
Identification of a partnership model between a university, for-profit, and not-for-profit organization to address health professions education and health inequality gaps through simulation-based education: A scoping review protocol
Authors: Siraj Samyah , Momand Beheshta , Brunton Ginny , Dubrowski Adam
Published: July 2023

Introduction

Healthcare providers in rural and remote (R&R) areas of Canada do not have the same access to skills development and maintenance opportunities as those in urban areas. Simulation-based education (SBE) is an optimal technique to allow healthcare providers to develop and maintain skills. However, SBE is currently limited mainly to universities or hospital-based research laboratories in urban areas. The purpose of this scoping review is to identify a model, or components of a model, that outline how a university research laboratory can collaborate with a for profit and not-for-profit organization to facilitate the diffusion of SBE into R&R healthcare provider training.

Methods and analysis

This scoping review will be guided by the methodological framework introduced by Arksey and O’Malley in 2005 and the Methodology for Joanna Briggs Institute Scoping Reviews. Ovid MEDLINE, PsycINFO, Scopus, Web of Science, and CINAHL will be searched for relevant articles published between 2000 and 2022, in addition to grey literature databases and manual reference list searches. Articles describing a partnership model or framework between academic institutions and non-profit organizations with a simulation or technology component will be included. Titles and abstracts will be screened, followed by a full-text screening of articles. Two reviewers will participate in the screening and data extraction process for quality assurance. Data will be extracted, charted, and summarized descriptively to report key findings on potential partnership models.

Conclusion

This scoping review will provide an understanding on the extent of existing literature regarding the diffusion of simulators for healthcare provider training through a multi-institutional partnership. This scoping review will benefit R&R parts of Canada by identifying gaps in knowledge and determining a process to deliver simulators to train healthcare providers. Findings from this scoping review will be submitted for publication in a scientific journal.
Type-I interferons promote innate immune tolerance in macrophages exposed to Mycobacterium ulcerans vesicles
Authors: Bernard Quentin , Goumeidane Maïssa , Chaumond Emmanuel , Robbe-Saule Marie , Boucaud Yan , Esnault Lucille , Croué Anne , Jullien Jerome , Marsollier Laurent , Marion Estelle
Published: July 2023

Buruli ulcer is a chronic infectious disease caused by Mycobacterium ulcerans. The pathogen persistence in host skin is associated with the development of ulcerative and necrotic lesions leading to permanent disabilities in most patients. However, few of diagnosed cases are thought to resolve through an unknown self-healing process. Using in vitro and in vivo mouse models and M. ulcerans purified vesicles and mycolactone, we showed that the development of an innate immune tolerance was only specific to macrophages from mice able to heal spontaneously. This tolerance mechanism depends on a type I interferon response and can be induced by interferon beta. A type I interferon signature was further detected during in vivo infection in mice as well as in skin samples from patients under antibiotics regiment. Our results indicate that type I interferon-related genes expressed in macrophages may promote tolerance and healing during infection with skin damaging pathogen.
A produção e conservação informacional de Maria do Carmo Barros Leite (1841-1911)
Authors: Couto Joana
Published: July 2023

No universo dos arquivos, a nível nacional e internacional, a produção e a conservação informacional feminina encontra-se menos estudada, principalmente, pelo facto da sua existência ser quantitativamente inferior ou por estar pouco visível. O presente artigo tem como caso de estudo o sistema informacional de Maria do Carmo Barros Leite (1841-1911), mulher de Teófilo Braga, antigo presidente da República Portuguesa. Procura através deste abordar as questões relacionadas com a produção e conservação informacional das mulheres, através da localização e recriação da informação produzida por esta figura feminina. Deste modo, faz-se uma reflexão sobre os dilemas que surgem aquando do tratamento arquivístico da documentação feminina e que soluções têm sido adotadas pela arquivística, tanto na prevenção da eliminação desses arquivos, como na sua conservação.
Mujeres, datos y poder. Una mirada al interior de la economía de las plataformas
Authors: Gutiérrez Miren
Published: July 2023

Mujeres, datos y poder. Una mirada al interior de la economía de las plataformas.
The contribution of data to feminist transformation of women’s rights to health
Authors: Sanz Urquijo Borja , López Belloso María
Published: July 2023

Digital technologies and data science have evolved rapidly. But how does the digital evolution affect women’s rights? Bunch argued that, to implement women’s rights, it was first necessary to observe how they are violated (Bunch, 1990). This article examines how femtec’s apps work, delivering reproductive and sexual health services to millions of women. Specifically, it analyzes the data collection permissions of 45 femtech apps to assess what the platform intends to do with the personal data collected and its objectives. To understand how these apps use data, we explored the goals of these apps in data collection and whether data could be collected and used to transform women’s health. Thus, this work is structured in four sections. First, a theoretical review of Bunch’s proposal and its contribution to data feminism is raised. Second, the potential for feminist transformation of human rights using digital technologies is discussed, particularly in women’s health. The third section details the current use of health data captured by health apps. This article ends by drawing the main conclusions of the analysis and providing recommendations for a feminist transformation of data activism from a human rights perspective.
Factores y rutinas profesionales que influyen en la visibilidad de las mujeres científicas en los medios digitales
Authors: Eizmendi Iraola Maider
Published: July 2023

Los estudios sobre la imagen mediática de las mujeres científicas han puesto el foco en el contenido. Este artículo examina las rutinas de trabajo de los y las periodistas que escriben sobre ciencia, así como la perspectiva de la ciencia que prima en las redacciones. El objetivo es conocer qué factores repercuten y de qué manera en la elaboración del mensaje que los medios digitales transmiten sobre las científicas. Basado en una metodología cualitativa, este trabajo ofrece los resultados de nueve entrevistas semiestructuradas a responsables de páginas web y expertos y expertas del ámbito de la comunicación, la ciencia y el género, además de una entrevista de grupo con siete periodistas que abordan temas científicos. Los resultados indican que la rapidez que impera en las redacciones no contribuye a una búsqueda pausada de las fuentes, un proceso que se ve influenciado, asimismo, por la mediación de los gabinetes de prensa y por la preponderancia de las áreas STEM. El estudio identifica tres pautas para impulsar un tratamiento adecuado de las científicas: el conocimiento y la transmisión de la situación de las mujeres en la ciencia a través de contenidos específicos; la promoción de su visibilidad tanto cuantitativamente como en lo referente a su estatus; y el tratamiento basado en la normalidad. El objetivo de estas directrices es afrontar las dificultades que los y las periodistas refieren a la hora de hallar fuentes femeninas y contribuir a disminuir los estereotipos y mejorar la imagen profesional de las mujeres científicas.
Stereotypes about mathematics and women: sex differences in mathematics anxiety of communication students
Authors: Berasategi Zeberio Miren
Published: July 2023

Citizens are required to understand an increasingly datafied reality to perform sensible decision making and be active participants in society. However, our ability to grasp that complexity, especially when it involves data in the form of numbers, is affected by limiting factors such as mathematics anxiety. In the case of women, how they face the reading of content based on data or numbers affects their daily lives, including career choice. Playing a central mediating role in transmitting increasingly datafied information, journalism is an interesting research object. This study examines the notion that journalism students –especially female students– are «bad with numbers» through the measurement of math anxiety of 185 Communication students, looking for correlations with their math competency. Results show that students manifest a low competency in math, paired with high math anxiety, which is the factor that best serves as an explanation for competency results. Specifically, only students with medium-low values of math anxiety pass the competency test. However, no sex differences were found in competency, while small differences in math anxiety (with women displaying slightly higher anxiety values than men) were identified. Even if the minor sex differences in math anxiety found in this study are not statistically significant, investigating whether this is also the case in other fields or in a random sample remains relevant, as these results defy previous misunderstandings of women’s capacities that are significant to understand the interactions of women with data.
Feminismo institucional y grupos de presión: relación entre el Lobby Europeo de Mujeres y el Gobierno de España
Authors: Mangas Santos Marta , Romero-Domínguez Lorena R.
Published: July 2023

El presente estudio se centra en comprobar la capacidad de influencia de los lobbies sobre los gobiernos. De manera concreta, tomamos como referencia el caso del Lobby Europeo de Mujeres (LEM, en adelante), seleccionado por ser la mayor entidad coordinadora de asociaciones de mujeres a nivel europeo, y sus conexiones con el Gobierno de España, conduciendo las necesidades de la sociedad en la consecución de políticas de igualdad entre mujeres y hombres desde lo particular al bien general. Procedemos, para identificar el grado de cooperación entre ambos, al análisis de la campaña «Movilízate contra el sexismo», desarrollada entre octubre de 2020 y enero de 2022. Se tendrán en cuenta diversas variables discursivas (los recursos y actividades empleados, los tipos de estrategias, las técnicas y herramientas comunicativas) para analizar el grado de adscripción a la defensa de la igualdad institucional y su plasmación en iniciativas legislativas del Gobierno de España y otros documentos vinculantes de organismos públicos dependientes del Estado. Debemos indicar, como resultado general, que las ideas de LEM España se difunden en dos formatos distintos, en lo audiovisual con los seminarios y en lo escrito con las propuestas, y que las redes sociales actúan como evidencia y principal herramienta comunicativa de la campaña. Los anuncios y mensajes que se difunden en redes sociales suelen ser efectivos, sobre todo si estos son publicados por el Instituto de las Mujeres, dando voz a las acciones e intereses de LEM España. Asimismo, se identifican paralelismos entre las recomendaciones realizadas en los seminarios de la campaña analizada y algunas de las actividades legislativas recientes del Gobierno en materia de igualdad.
The mediating role of burnout syndrome between regulatory focus/motivation and intention to leave in teachers
Authors: Carlotto Mary Sandra , Gonçalves Sónia P. , Geremias Rosa Lutete , Câmara Sheila Gonçalves
Published: July 2023

Teachers are exposed to various occupational stressors which, if persistent, can lead to Burnout Syndrome and to recurrent thoughts of leaving the profession and culminate in total withdrawal. Thus, the objective of the present study was to evaluate the mediating role of Burnout Syndrome between the two dimensions motivational system that is constituted by the regulatory system with a focus on prevention and promotion and the Intention to Leave the profession among teachers in Southern Brazil. A total of 781 elementary school teachers from public and private schools participated in the research. The research instruments used included the Burnout Syndrome Questionnaire, the Regulatory Focus Scale, and a single item to evaluate the Intention to Leave the profession. The results obtained by Structural Equation Modeling confirmed the hypothesis that Burnout Syndrome plays a mediating role between promotion regulatory focus and the Intention to Leave the profession. The results reveal the importance of interventions that contemplate the reduction of occupational stressors for the prevention or rehabilitation of Burnout Syndrome in teachers.
IMPLEMENTATION OF INDEPENDENT LEARNING CURRICULUM AS A 21st CENTURY LEARNING MODEL IN HIGHER EDUCATION
Authors: Dwi Lutfi Nur Anisa
Published: July 2023

This study aims to describe the implementation of independent learning curriculum in higher institutions. The independent learning curriculum is newly implemented to respond to the needs of industry 4.0. The Independent learning curriculum is implemented by applying student-centered learning. Students are free to choose the field of science they are interested in even though they are cross-departmental. The method used is a systematic review using the prism method by analyzing research manuscripts. The steps in a systematic review using the Prisma model include; defining eligibility criteria, defining sources of information, selecting literature, collecting data, and selecting data items. Based on the results of the review, it was found that the independent learning curriculum can answer the challenges of industry 4.0. The implementation of the independent learning curriculum is carried out through three aspects, namely, 1) collaboration of the campus curriculum with the independent learning curriculum, 2) the availability of learning facilities, and 3) the development of learning tools. The fulfillment of these three aspects will positively impact the multidisciplinary competence of students.
¿Puede la resurrección de los muertos preservar la identidad personal?
Authors: Romerales Espinosa Enrique
Published: July 2023

La creencia en la resurrección de los muertos es central para las religiones abrahámicas. Al estar actualmente desacreditada la noción de alma, muchos filósofos cristianos materialistas se replantean la posibilidad de tal resurrección. Dos problemas fundamentales amenazan tal posibilidad: la discontinuidad espacio-temporal entre la muerte y la resurrección (que impediría esta última si fuera imposible una existencia intermitente para los seres humanos) y la degeneración, disgregación o incluso completa destrucción de los componentes materiales del cuerpo (que impediría la reconstrucción del cuerpo original). Ambas cuestiones ponen en peligro la identidad numérica entre la persona muerta y la resucitada. Tras examinar diversas hipótesis recientes que intentan superar estas dificultades, constato que, o bien recurren a ideas disparatadas para asegurar la identidad, o asumen directamente que el cuerpo resucitado es una mera copia del original. Así, concluyo que, supuesta una concepción puramente corporalista de la persona, no parece viable ninguna noción de resurrección que preserve la identidad personal.
pureza como salvaguarda de la intimidad según L. Polo
Authors: Sellés Dauder Juan Fernando
Published: July 2023

Siguiendo la distinción tripartina en el hombre entre naturaleza corpórea, esencia y acto de ser personal, se trata de la virtud de la pureza o castidad y sus anejas, el pudor y la modestia, con referencia al cuerpo humano, a la voluntad y al corazón o intimidad humana siguiendo el pensamiento de L. Polo.
Europa 2000
Authors: Siebeck Jürgen E.
Published: July 2023

In den politischen Schlußfolgerungen des Dokuments “Europa 2000 – Perspektiven der künftigen Raumordnung der Gemeinschaft” schlägt die EG-Kommission im wesentlichen folgende Aktivitäten vor:– Maßnahmen zur Informationsverbesserung über Daten und Vorgänge mit Relevanz für Raumordnungsfragen auf europäischer Ebene;– die Einrichtung eines Ausschusses zur Raumentwicklung, um die gegenseitige Konsultation zu erleichtern;– die Sammlung sozioökonomischer Informationen über die Regionen;– die bessere Information der Planungsverantwortlichen über die Absichten ihrer Kollegen bezüglich größerer Infrastrukturmaßnahmen;– ein System zur Beobachtung und Aktualisierung raumrelevanter Informationen in Zusammenarbeit mit den Forschungsinstitutionen in den Mitgliedstaaten;– die weitere Entwicklung eines Geographischen Informationssystems (GIS);– spezifische Bereiche für Gemeinschaftsinterventionen■ in Grenzregionen (Binnengrenzen und externe Grenzen),■ zur Förderung von Kooperation zwischen Regionen und Städten,■ zur Schließung von fehlenden Verbindungsstücken in den transeuropäischen Netzen (vor allem zwischen der Peripherie und dem Zentrum),■ in innerstädtischen Problemfeldern (soziale Integration und Umwelt).Die für Regionalpolitik und Raumordnung zuständigen Minister haben auf ihrer informellen Sitzung am 18./19. November 1991 in Den Haag nicht nur das von der Kommission vorgelegte Dokument begrüßt, sondern auch den dort enthaltenen Vorschlägen weitgehend zugestimmt.
EG-Regionalpolitik und Wirtschaftsförderung in Griechenland
Authors: Ridder Michael
Published: July 2023

Die griechische regionale Wirtschaftspolitik konzentriert sich im wesentlichen auf klassische Formen der Wirtschaftsförderung (Akquirierung von Betrieben und Schaffung technischer Infrastrukturen), die in den 80er Jahren wesentlich durch die finanzielle Unterstützung des Europäischen Fonds für Regionale Entwicklung (EFRE) beeinflußt wurde. In der Region Thrakien konnten dabei keine durchgreifenden Impulse für eine endogene regionale Wirtschaftsentwicklung registriert werden. Auch neuere Ansätze der Programm-Implementierung, die auch Maßnahmen zur Förderung des Innovationspotentials und Beratungsdienste einbeziehen, zeigen eine nur geringe positive Wirkung der EG-Regionalpolitik. Die strategische Vorbereitung Thrakiens auf den europäischen Binnenmarkt durch strukturpolitische Programme muß insgesamt als ungünstig bezeichnet werden.
Makroökonomische Evaluierung regionaler Wirtschaftspolitik, dargestellt am Beispiel Bremen
Authors: Gräber Heinrich
Published: July 2023

ln dem Beitrag werden die makroökonomischen Wirkungen des wirtschaftsstrukturpolitischen Aktionsprogrammes für Bremen und Bremerhaven bis 1995 (WAP 95) herausgearbeitet und quantifiziert. Damit wird ein Beitrag zur wissenschaftlichen Evaluierung der WAP-Programmatik geleistet. Im Mittelpunkt steht eine Wirkungs- und Effizienzkontrolle der bremischen Wirtschaftspolitik im Zeitraum 1984–1991, welche die politikinduzierten Wirkungen auf Beschäftigung, Wertschöpfung und Steueraufkommen von den sonstigen Einflußfaktoren auf diese regionalen Zielgrößen zu isolieren versucht. Vom Ergebnis her werden statistisch signifikante und quantitativ beachtliche WAP-Wirkungen herausgearbeitet. Der in dem Beitrag entwickelte theoretische Bezugsrahmen, der verwendete methodische Ansatz zur Isolierung der Politik-Wirkungen, der Exkurs über den sog. Mitnahmeeffekt sowie die fiskalische Analyse unter Einbeziehung von Finanzausgleichs-Effekten machen den Beitrag über den spezifischen Bremen-Aspekt hinaus interessant.
Die Folgen der Bundeswehrreduzierung für die Beschäftigung in der Region Schleswig
Authors: Zühlke-Robinet Klaus
Published: July 2023

Die Reduzierung der Bundeswehrpräsenz in der Region Schleswig führt nicht zu einem unmittelbaren Anstieg der Zahl der Arbeitslosen. Auch mit nennenswerten Entlassungen ist nicht zu rechnen. Denn der Großteil der überzähligen Bundeswehrbeschäftigten in den untersuchten Gebieten wird in den (Vor‑)Ruhestand gehen können. Weitere Beschäftigungswirkungen resultieren aus dem Rückgang der Garnisonsausgaben sowie daraus, daß mit der möglichen Abwanderung von ausscheidenden Bundeswehrbeschäftigten ein Kaufkraftausfall eintritt, der zu Lasten der Beschäftigung im Einzelhandel gehen kann. Die Beschäftigungsfolgen lassen sich minimieren, wenn der unmittelbar wirksame Beschäftigungsverlust zügig kompensiert werden kann.
Energieberatung als Beitrag zur Regionalentwicklung
Authors: Kaiser Mathias
Published: July 2023

Die erarbeitete Energieberatungskonzeption greift die in der Fachdiskussion verbreitete Kritik an Energieversorgungskonzepten (EVK) auf, die sich auf die bestehenden Vollzugsdefizite bezieht. Sie stellt ein wesentliches Umsetzungsinstrument für EVK dar und ist gleichzeitig als inhaltliche Erweiterung derselben zu begreifen. Bereiche der Regionalplanung, die sonst bei der Erstellung von EVK nur eine untergeordnete Rolle spielen, wie die Eingliederung in ein regionales Entwicklungsleitbild und die Anwendung neuer Formen von Kooperation, finden hier eine starke Berücksichtigung. Für Energieplanung wird damit das geleistet, was in anderen Raumplanungsbereichen schon eine länger anhaltende Entwicklung ist, daß nämlich Planung selbst sich entfernt von der reinen Entwurfs- und Konzepterstellung als Eigenprodukt hin zu der Tendenz, daß Aushandlungs- und Planungsprozesse immer mehr zum Inhalt der Planung hinzukommen (Bargaining). Dabei sind EVK als Instrumente der Energieplanung grundsätzlich nicht als überflüssig, sondern als fachliche und sachliche Grundlage für die vorgelegte Umsetzungskonzeption anzusehen.
Umwelt und Regionalentwicklung in den neuen Ländern
Authors: Wiegandt Claus-C.
Published: July 2023

Ziel dieses Beitrags ist es, die engen Verflechtungen von Umweltbedingungen und Regionalentwicklung in den neuen Ländern herauszuarbeiten. Auf der einen Seite droht die schlechte Umweltsituation zu einer Restriktion der Entwicklung in den neuen Ländern zu werden, auf der anderen Seite besteht die Gefahr, daß eine zu schnelle, rein ökonomisch ausgerichtete Regionalentwicklung soziale und ökologische Belange nicht ausreichend berücksichtigt und die Umweltbedingungen langfristig negativ beeinträchtigt. Zu einem besseren Verständnis dieser Prozesse werden deshalb im ersten Abschnitt knapp die derzeitige Umweltsituation sowie im zweiten Teil einige Aspekte zur Regionalentwicklung in den neuen Ländern skizziert. Anschließend werden im dritten Teil einige Gedanken zum Einfluß derUmweltsituation auf eine mögliche Regionalentwicklung vorgestellt, um dann im vierten Teil umgekehrt die Konsequenzen der Regionalentwicklung für die Umweltsituation zu hinterfragen. Ein kurzes Fazit soll am Ende des Beitrags stehen.
Konflikte beim Ausbau der italienischen Raumplanung
Authors: Kneissl Rabossi Silvia
Published: July 2023

Der gesamte Bereich der überörtlichen Raumplanung war bis in die 70er Jahre in ausschließlicher Kompetenz dem italienischen Zentralstaat zugesprochen, der mit relativ einfacher Verrechtlichung und inhaltlicher Limitierung der Aufgabenstellung seine Ziele vornehmlich auf der lokalen Ebene durchzusetzen suchte. Dabei war das institutionelle Verständnis der Raumplanungsaufgabe vorwiegend als fachplanerische Disziplin interpretiert worden, die temporär von den unterschiedlichen Politikbereichen wahrgenommen werden sollte. Die vorhandenen Organisationsstrukturen sahen dabei kaum planerische Teilräume vor.Erst im Rahmen der umfassenden Funktionalreform, die im Zeitraum 1972 bis 1977 realisiert wurde, erhielten die „Regioni“ in ihrer Ausstattung als konstitutionelle Gebietskörperschaften neben anderen auch die Kompetenz für die „Urbanistica“ zugesprochen und somit die Möglichkeit, organisatorisch und legislativ eine eigene Raumplanung aufzubauen. Mit den staatlichen Aufgabenträgern, die bis dato mehr als Bau- denn als Raumordnungsträger gewirkt hatten, gerieten die neuen Planer bald in Konkurrenzsituationen, in denen sich Konfliktpotentiale entwickelten. Die einsetzende Phase der Klärung von Zuständigkeitsfragen ist bislang noch nicht abgeschlossen und prägt, bei anhaltender Dualität der Interessenlagen, das Bild der raumplanerischen Umfeldbedingungen.
Improvement of Patients’ Knowledge, Attitude, and Practice on Tuberculosis Treatment Using Video and Leaflet
Authors: Dameria Dameria , Hulu Victor Trismanjaya , Siregar Santy Deasy , Manalu Putranto , Samosir Frans Judea , Rambe Fadilah Ummul Choiriyah , Hasibuan Nadilla
Published: July 2023

Background: The effectiveness of Tuberculosis (TB) treatment outcomes for patients is currently suboptimal, posing a significant challenge to comprehensive efforts aimed at eradicating the disease. To address this problem, several studies have proposed that the implementation of health education initiatives have the potential to enhance treatment adherence and behavior of patients. Therefore, this study aims to assess the efficacy of health education programs using video and leaflet modalities.Method: This was a quasi-experimental study with a non-randomized pretest-posttest control group design. The sample population consisted of 85 TB patients at the Kenanga Health Center, Tegal Sari Mandala II, Medan Denai District, Medan City in 2022. Furthermore, the samples size was obtained using a purposive sampling method, involving 64 patients, which were evenly divided into two groups, namely intervention and control. The controls and intervention groups were educated using leaflet and video media, respectively. Pre-test and post-test were given to all the participants using the same instrument. A post-test was administered on the twenty-fifth day, where the materials were the same as those used at the pre-test stage. The data collected in this study were analyzed using the Wilcoxon, Mann-Whitney, and N-Gain tests.Results: There were significant differences between knowledges, attitudes, and practices of the participants before and after being given the interventions. Furthermore, knowledges, attitudes, and practices scores increased after the interventions were administered. Based on the results, health education using video (N-Gain score of 76.82) improved behavior of TB patients compared to the use of leaflet (N-Gain score of 49.74). After being educated, people with TB were expected to exhibit higher treatment adherence and adoption of healthy lifestyles.
Oxygen excess ratio control of PEM fuel cell: fractional order modeling and fractional filter IMC-PID control
Authors: Siva Mullapudi , Puttapati Sampath Kumar , Araga Ramya , Sharma Shubhanshu , Patle Dipesh S. , Uday Bhaskar Babu Gara
Published: July 2023

Concerning global warming, an energy-efficient power source must produce low or no pollutant emissions and provide an unlimited fuel supply. Proton Exchange Membrane fuel cell (PEMFC) is an electrochemical device that transforms chemical energy into electrical energy. The performance and durability of PEM fuel cells are affected by voltage reversals and fuel starvation. Oxygen Excess Ratio (OER) is a crucial factor in controlling the fuel starvation of the PEMFC system. First, this work identified the PEMFC as an integer order and fractional-order first order plus time delay models using the predictor error method and Grunwald–Letnikov simulation method based on a trust-region-reflect algorithm, respectively. Fractional order models more accurately represented the PEM fuel cell system dynamics. Then, robust fractional filters cascaded with PID controllers based on the Internal Model Control scheme (IMC) are designed for identified integer and fractional order models to regulate the OER by compressor voltage manipulation. The genetic Algorithm (GA) optimization technique is used to find the optimal fractional filter tuning parameters. The proposed controller’s performance regarding Integral Absolute Error (IAE) and Total Variance (TV) is analyzed. Furthermore, the robustness of a perturbed plant and fragility with perturbed controllers are elucidated. The results show that a fractional filter cascaded with fractional order PID controller improves the performance compared to a fractional filter cascaded with integer order PID controllers.
Choosing opponents in skiing sprint elimination tournaments
Authors: Lunander Anders , Karlsson Niklas
Published: July 2023

In this study we analyse data from world cup cross-country skiing sprint elimination tournaments for men and women in 2015–2020. Instead of being assigned a quarterfinal according to a seeding scheme, prequalified athletes choose themselves in sequential order in which of the five quarterfinals to compete. Due to a time constraint on the day the competition is held, the recovery time between the elimination heats varies. This implies a clear advantage for the athlete to race in an early rather than in a late quarterfinal to maximize the probability of reaching the podium. The purpose of the paper is to analyse the athletes’ choices facing the trade-off between recovery time and expected degree of competition when choosing in which quarterfinal to compete. We find empirical support for the prediction that higher ranked athletes from the qualification round prefer to compete in early quarterfinals, despite facing expected harder competition. Nevertheless, our results also suggest that athletes underestimate the value of choosing an early quarterfinal. In addition, we propose a seeding scheme capturing the fundamental disparity across quarterfinals using the estimates from alogistic regression model.