bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ROLE OF E-LEARNING INFRASTRUCTURE AND COGNITIVE COMPETENCE IN DISTANCE LEARNING EFFECTIVENESS DURING THE COVID-19 PANDEMIC
Authors: Garad Askar , Al-Ansi Abdullah M. , Qamari Ika Nurul
Published: March 2021

Covid-19 has led to the closure of educational institutions around the world and turned formal learning into distance learning. This study aims to investigate the effect of e-learning infrastructure and individual’s knowledge and competence on distance learning during the Covid-19 pandemic outbreak in 2020. E-learning infrastructure and individual’s cognitive competence were also used to determine the readiness of educational institutions in distance learning. The e-learning infrastructure includes Learning Management System (LMS), electronic devices, communication applications, and internet accessibility. Quantitative approach was used in this study with a sample of 324 participants from three major universities in Yogyakarta, Indonesia. Data were collected through online surveys. The descriptive statistical approach and one-layer regression analysis were used to examine the problems raised in this study. The results show that distance learning is positively influenced by e-learning infrastructure and the cognitive competence of the students, the faculty, and administrative staff. The results also point out the university’s readiness level in adopting online learning based on their previous experience of using the learning system. Finally, the study proposes that in order to improve the e-learning process, there needs to be sufficient financial support from the government, whereas the universities are advised to conduct workshops and training, and to provide teleconferencing applications.
Adoption of unified electronic health record in Saudi Arabia: The residents perspective
Authors:   Department of Health Informatics, College of Public Health and Health informatics, University of Ha’il, Ha’il, Saudi Arabia, Alshammari Muteb H.
Published: March 2021

The government of Saudi Arabia has been working on the development of eHealth in the country which includes, the move from paper-based health records to Electronic Health Records (EHR). But, the implementation of EHR in the country is not much progressed. The present paper aims to measure adopting a unified electronic health record in Saudi Arabia from the resident's perspective. The descriptive study was conducted by the survey method in Saudi Arabia. The primary data was collected using a structured questionnaire. Self-administered online questionnaires were distributed to 300 respondents in various provinces via social media over a period of three months. The study used a Convenient Sampling technique and received 158 valid questionnaires from the respondents with a response rate of 58.66%. The data were analyzed using SAS version 0.4. The results show that 98.07% of the male participants and 88.88% of the female respondents were expressed their acceptance towards the adoption of EHR at the national level, whereas 68.26% of the male and 66.66% of the female respondents were expressed their acceptance at the global level. The study conducted the Logistic Regression and found no statistically significant differences between the gender, region, and education level of the respondents and acceptance of adoption of unified EHR at the national and global level. The study found that Saudi Arabia residents are supporting the adoption of unified EHR at both national and global levels. The findings are useful for policymakers to understand the people’s perceptions about the adoption of unified EHR in the country.
Acute Care Decision-Making for Patients with Advanced Dementia: An Exploratory Study Using Cognitive Task Analysis
Authors:   Henrietta Szold Hadassah University School of Nursing, Kiryat Hadassah, POB 12000, Jerusalem, 91120, Israel, Erel Meira , Marcus Esther-Lee , Ganz Freda DeKeyser
Published: March 2021

Decision-making by medical and health care staff forms the core of professional practice. Thought processes, including non-clinical considerations, significantly impact how clinical decisions are made. Such considerations become more relevant when addressing end-of-life care decisions for patients with advanced dementia (PAD). Though palliative care is recommended for this population, its implementation tends to vary. Given the medical staff’s significant influence in guiding clinical decisions, we examined thought processes that accompany staff decisions. We used Cognitive Task Analysis (CTA) to analyze interviews conducted with 15 physicians and 11 nurses working in acute care wards in Central Israel. Participants were interviewed regarding their clinical decision-making in a hypothetical scenario of a PAD who presents with an acute, potentially life-threatening medical problem. Moral judgment orientation was the primary factor affecting clinical decision-making for advanced dementia, with a pronounced dichotomous split between deontological and utilitarian approaches. This polarization was highly associated with the medical specialty. Practitioners in surgical wards tended to focus on the patient’s current medical condition, as an isolated or disease-centered illness perspective, supported by deontological moral lines of thinking. This perspective was contrary to that of staff in medical wards who mostly treated the patient from a holistic perspective with a patient-focus approach, supported by utilitarian moral lines of thinking. Although all respondents presented the patient or family as primary decision partners, the practitioners were motivated to make decisions based on unit hierarchies or positions of authority figures. Therefore, clinical end-of-life decisions are influenced by different thinking processes of the health staff and several non-clinical factors. The moral thinking paradigm was found to be associated with a professional orientation. Understanding the subjective, non-clinical aspects of decision-making for PAD might improve end-of-life care in this population.
Use of #SaludTues Tweetchats for the Dissemination of Culturally Relevant Information on Latino Health Equity: Exploratory Case Study (Preprint)
Authors: Ramirez Amelie G , Aguilar Rosalie P , Merck Amanda , Despres Cliff , Sukumaran Pramod , Cantu-Pawlik Stacy , Chalela Patricia
Published: March 2021

BACKGROUND

Latinx people comprise 18% of the US adult population and a large share of youth and continue to experience inequities that perpetuate health disparities. To engage Latinx people in advocacy for health equity based on this population’s heavy share of smartphone, social media, and Twitter users, Salud America! launched the #SaludTues Tweetchat series. In this paper, we explore the use of #SaludTues to promote advocacy for Latinx health equity.

OBJECTIVE

This study aims to understand how #SaludTues Tweetchats are used to promote dissemination of culturally relevant information on social determinants of health, to determine whether tweetchats serve to drive web traffic to the Salud America! website, and to understand who participates in #SaludTues Tweetchats and what we can learn about the participants. We also aim to share our own experiences and present a step-by-step guide of how tweetchats are planned, developed, promoted, and executed.

METHODS

We explored tweetchat data collected between 2014 and 2018 using Symplur and Google Analytics to identify groups of stakeholders and web traffic. Network analysis and mapping tools were also used to derive insights from this series of chats.

RESULTS

We conducted 187 chats with 24,609 reported users, 177,466 tweets, and more than 1.87 billion impressions using the hashtag #SaludTues during this span, demonstrating effective dissemination of and exposure to culturally relevant information. Traffic to the Salud America! website was higher on Tuesdays than any other day of the week, suggesting that #SaludTues Tweetchats acted effectively as a website traffic–driving tool. Most participants came from advocacy organizations (165/1000, 16.5%) and other health care–related organizations (162/1000, 16.2%), whereas others were unknown users (147/1000, 14.7%) and individual users outside of the health care sector (117/1000, 11.7%). The majority of participants were located in Texas, California, New York, and Florida, all states with high Latinx populations.

CONCLUSIONS

Carefully planned, culturally relevant tweetchats such as #SaludTues can be a powerful tool for public health practitioners and advocates to engage audiences on Twitter around health issues, advocacy, and policy solutions for Latino health equity. Further information is needed to determine the effect that #SaludTues Tweetchats have on self- and collective efficacy for advocacy in the area of Latino health equity.

CLINICALTRIAL
Effectiveness of Mobile Health Interventions on Management of Patients with Hypertension: Systematic Review of Systematic Reviews (Preprint)
Authors: Wu Sisi , Long Chunhua , Li Shasha , Tu Xuemei
Published: March 2021

BACKGROUND

Mobile health (mHealth) has provided a powerful platform for chronic disease management recent years. Although some previous systematic reviews evaluated the effectiveness of mHealth on hypertension management, there were inconsistent findings.

OBJECTIVE

To systematically evaluate the effectiveness of mHealth interventions on the management of patients with hypertension and to provide recommendations for the clinic and future researches.

METHODS

Databases including Embase, Cochrane Library, CINAHL, CNKI, SinoMed, WanFang and VIP Database were searched to collect systematic reviews and meta-analysis on mHealth interventions for hypertension management. Two researchers independently screened the articles and extracted data, and the Measurement Tool to Assess Systematic Reviews (AMSTAR 2) was used to evaluate the methodological quality of the included reviews.

RESULTS

A total of 11 systematic reviews were included. Three reviews were rated as high quality, four moderate quality, three low quality, one critically low quality. Mobile phone was the most common intervention type, followed by the internet. Seven reviews performed meta-analysis and showed that mHealth was associated with significant reduction in SBP from 2.28mmHg(95%CI 0.66-3.90; I2=100%) to 14.77 mmHg(95%CI 11.76-17.77; I2=90%) and DBP from 1.50mmHg(95%CI 0.80-2.20; I2=62%) to 8.17 mmHg(95%CI 5.67-10.67; I2=86%). Self-management behaviors included medication adherence, diet, smoking, alcohol drinking, exercise and BP monitoring, there were inconsistent results on the effectiveness of mHealth interventions.

CONCLUSIONS

The mHealth interventions can improve BP control in patients with hypertension, but its impact on self-management behaviors is not confirmed.
Effect of Community-Based Kangaroo Mother Care Package on Neonatal Mortality Among Preterm and Low Birthweight Infants in Rural Pakistan: Protocol for a Cluster Randomized Controlled Trial (Preprint)
Authors: Ariff Shabina , Habib Atif , Memon Zahid , Arshad Tayyaba , Samejo Tariq , Maznani Ikram , Umer Muhammad , Hussain Amjad , Rizvi Arjumand , Ahmed Imran , Soofi Sajid Bashir , Bhutta Zulfiqar A
Published: March 2021

BACKGROUND

Neonatal mortality due to preterm birth and low birthweight remains a significant challenge in Pakistan. Kangaroo mother care (KMC) is a unique, low-cost intervention proven to reduce neonatal mortality and morbidity and increase exclusive breastfeeding rates. However, KMC has not been attempted in community settings in Pakistan. We aim to implement and evaluate the effectiveness of a community-based KMC package to reduce neonatal morbidity and mortality among preterm and low birthweight (LBW) infants, which will provide evidence for policy development and the large-scale implementation of KMC across the country.

OBJECTIVE

The primary objective of this trial is to reduce neonatal mortality among preterm and LBW infants. The secondary objectives are growth (measured as weight gain), reduced incidence of possible serious bacterial infection, and increased exclusive breastfeeding and continued breastfeeding practices.

METHODS

We designed a community-based cluster randomized controlled trial in one rural district of Pakistan. Stable, LBW babies (weighing 1200 grams to 2500 grams) are included in the study. The community KMC package, consisting of the KMC kit, information and counseling material, and community mobilization through KMC champions (village volunteers), was designed after preliminary research in the same geographical location and implemented in intervention clusters. The standard essential newborn care is offered in the control clusters. Infants are recruited and followed up by independent teams of data collectors. Data are collected on the duration of skin-to-skin contact, growth, breastfeeding practices, morbidities, neonatal mortality, and neurodevelopment status. Data analysis will be conducted based on the intention to treat principle. The Cox regression model will be used to assess the primary outcome of neonatal mortality. The secondary outcomes will be evaluated using linear or logistic regression.

RESULTS

The Ethics Review Committee of Aga Khan University, Pakistan, approved the study protocol in February 2017. Data collection began in August 2019 and will be completed in December 2021. Data analyses are yet to be completed.

CONCLUSIONS

This intervention may be effective in preventing sepsis and subsequently improve survival in LBW newborns in Pakistan and other low-income and middle-income countries worldwide.

CLINICALTRIAL

clinicaltrials.gov NCT03545204; https://clinicaltrials.gov/ct2/show/NCT03545204

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/28156
What goes on in digital behaviour change interventions for weight loss maintenance targeting physical activity: A Scoping Review (Preprint)
Authors: Encantado Jorge , Palmeira António L. , Silva Carolina , Sniehotta Falko F. , Stubbs R. James , Gouveia Maria J. , Teixeira Pedro J. , Heitmann Berit L. , Marques Marta M.
Published: March 2021

BACKGROUND

Behavioural interventions for weight loss maintenance have shown beneficial effects for weight loss maintenance. While the digital upgrade of behavioural interventions brings an enormous potential to tackle public health challenges, there is limited knowledge about the components of these interventions, i.e., its content, delivery and the theoretical approaches.

OBJECTIVE

To identify the core components of digital behaviour change interventions for weight loss maintenance targeting physical activity, in terms of: i) Behaviour Change Techniques; ii) Mechanisms of Action; iii) Modes of Delivery; iv) Dose; and v) Tailoring/Personalisation. In addition, the links between these components were investigated.

METHODS

A literature search was performed in 5 electronic databases: PubMed; Embase; CINHAL; PsycINFO, and Web of Science. Two reviewers independently screened the identified papers and extracted data related with the study characteristics and behaviour change techniques, mechanism of action, mode of delivery, dose, and tailoring, using standardized classifications whenever available (e.g., behaviour change techniques taxonomy).

RESULTS

Seventeen articles reporting eleven original studies were selected. Two studies were protocols, nine studies presented results for weight change and all but one showed no significant differences between the intervention and control groups. Eight studies (73%) provided adequate information on Behaviour Change Techniques. Five studies (45%) provided partial information about how the Behaviour Change Techniques were linked to mechanisms of action, and only one study (0.9%) described these links for all the techniques. Around half of the studies reported the modes through which behaviour change techniques were delivered. Descriptions of dose were present in most studies, but with minimal information. The use of tailoring or personalisation approaches was mentioned in eight studies (73%), but descriptions of what was tailored and how were minimal.

CONCLUSIONS

The compilation of information regarding intervention components was difficult due to the lack of information and systematisation in reporting across papers. This is particularly true for the reporting of the links between behaviour change techniques and the other core intervention components. This information is crucial to help us understand in the context of behaviour change interventions what works or does not work, how it works and why.
Outcomes of Digital Biomarker–Based Interventions: Protocol for a Systematic Review of Systematic Reviews (Preprint)
Authors: Motahari-Nezhad Hossein , Péntek Márta , Gulácsi László , Zrubka Zsombor
Published: March 2021

BACKGROUND

Digital biomarkers are defined as objective, quantifiable, physiological, and behavioral data that are collected and measured using digital devices such as portables, wearables, implantables, or digestibles. For their widespread adoption in publicly financed health care systems, it is important to understand how their benefits translate into improved patient outcomes, which is essential for demonstrating their value.

OBJECTIVE

The paper presents the protocol for a systematic review that aims to assess the quality and strength of the evidence reported in systematic reviews regarding the impact of digital biomarkers on clinical outcomes compared to interventions without digital biomarkers.

METHODS

A comprehensive search for reviews from 2019 to 2020 will be conducted in PubMed and the Cochrane Library using keywords related to digital biomarkers and a filter for systematic reviews. Original full-text English publications of systematic reviews comparing clinical outcomes of interventions with and without digital biomarkers via meta-analysis will be included. The AMSTAR-2 tool will be used to assess the methodological quality of these reviews. To assess the quality of evidence, we will evaluate the systematic reviews using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) tool. To detect the possible presence of reporting bias, we will determine whether a protocol was published prior to the start of the studies. A qualitative summary of the results by digital biomarker technology and outcomes will be provided.

RESULTS

This protocol was submitted before data collection. Search, screening, and data extraction will commence in December 2021 in accordance with the published protocol.

CONCLUSIONS

Our study will provide a comprehensive summary of the highest level of evidence available on digital biomarker interventions, providing practical guidance for health care providers. Our results will help identify clinical areas in which the use of digital biomarkers has led to favorable clinical outcomes. In addition, our findings will highlight areas of evidence gaps where the clinical benefits of digital biomarkers have not yet been demonstrated.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/28204
Smartphone-RCCT Database: A repository of Randomized Controlled Clinical Trials of Smartphone Applications for Chronic Conditions (Preprint)
Authors: Barth Jürgen , Wang Jiani , Lopez-Alcade Jesus , Kramm Christoph , Pach Daniel , Álvarez-Díaz Noelia , Grifol-Clar Eulàlia , Witt Claudia M.
Published: March 2021

BACKGROUND

Chronic conditions have a big impact on disability, morbidity, and mortality worldwide. Smartphone health applications (apps) have the potential to improve the health of patients with chronic conditions and to enhance the quality and efficiency of healthcare. The number of randomized controlled trials (RCTs) of smartphone health apps is increasing but a collection of the available evidence in one database is still missing.

OBJECTIVE

To describe Smartphone-RCCT, which is a database of randomized controlled clinical trials (RCTs) of smartphone apps for chronic conditions.

METHODS

Smartphone-RCCT is an open-access database collecting bibliographic references and important characteristics of RCTs. For a study to be included, the following criteria had to be met: a) RCT published in a peer-reviewed journal; b) adult study participants with one or several chronic conditions that represent the main health problem addressed by the study intervention. c) Intervention: smartphone health app used by the patient. d) Comparator: any control condition. e) Outcomes: any patient-reported health outcome (studies exclusively measuring the patients’ knowledge about the chronic conditions or their satisfaction with the smartphone app were excluded). f) Sample size: at least 15 participants per study arm. We searched in electronic databases and other resources to identify relevant studies. Two reviewers selected the studies and extracted data independently.

RESULTS

The database is available in Open Science Framework (OSF): https://osf.io/nxerf/. Annual updates are planned.

CONCLUSIONS

Smartphone-RCCT is the first systematic open-access database collecting peer-reviewed publications of RCTs of smartphone apps for patients with chronic conditions. The database accelerates the delivery of evidence-based information in a dynamic research field. It represents an essential resource for different stakeholders, such as professionals working in evidence synthesis, meta-epidemiological studies, or planning a RCT.

CLINICALTRIAL

https://osf.io/nxerf/
Causal Effects of Alcohol-Related Facebook Posts on Drinking Behavior: Longitudinal Experimental Study (Preprint)
Authors: Hendriks Hanneke , de Nooy Wouter , Gebhardt Winifred A , van den Putte Bas
Published: March 2021

BACKGROUND

Adolescents and young adults frequently post alcohol-related content (ie, alcoholposts) on social media. This is problematic because both social norms theory and social learning theory suggest that viewing alcoholposts of peers could increase drinking behavior. It is therefore paramount to understand the effects of exposure to alcoholposts on viewers.

OBJECTIVE

This study aimed to investigate the causal effects of exposure to alcoholposts on alcohol consumption by using a rigorous design.

METHODS

We conducted a 6-week longitudinal study during which alcoholposts were measured by a newly developed app that copied Facebook posts shared by participants (n=281) to a new social media environment. In addition, daily questionnaires assessed alcohol use. Effects of natural alcoholposts (ie, posted by the participants) were assessed in phase 1, and effects of experimental posts (ie, posted by fake participants) were explored in phase 2.

RESULTS

Results showed that natural alcoholposts increased the occurrence and quantity of drinking the following day. That is, exposure to a single additional alcoholpost increased the log odds of drinking the next day by 0.27 (b=.27, credible interval [CI] .18 to .35). Furthermore, the number of natural alcoholposts had a positive (predictive) effect on the number of glasses drunk the next day (b=.21, CI .14 to .29). In phase 2 when experimental posts were also present, these effects decreased. Experimental posts themselves had hardly any effects.

CONCLUSIONS

This study illustrates clear and direct effects of exposure to alcoholposts on next-day alcohol consumption and suggests that alcoholposts represent an important societal problem that interventions need to address.
Drug-Drug Interaction Predictions via Knowledge Graph and Text Embedding: Instrument Validation Study (Preprint)
Authors: Wang Meng , Wang Haofen , Liu Xing , Ma Xinyu , Wang Beilun
Published: March 2021

BACKGROUND

Minimizing adverse reactions caused by drug-drug interactions (DDIs) has always been a prominent research topic in clinical pharmacology. Detecting all possible interactions through clinical studies before a drug is released to the market is a demanding task. The power of big data is opening up new approaches to discovering various DDIs. However, these data contain a huge amount of noise and provide knowledge bases that are far from being complete or used with reliability. Most existing studies focus on predicting binary DDIs between drug pairs and ignore other interactions.

OBJECTIVE

Leveraging both drug knowledge graphs and biomedical text is a promising pathway for rich and comprehensive DDI prediction, but it is not without issues. Our proposed model seeks to address the following challenges: data noise and incompleteness, data sparsity, and computational complexity.

METHODS

We propose a novel framework, Predicting Rich DDI, to predict DDIs. The framework uses graph embedding to overcome data incompleteness and sparsity issues to make multiple DDI label predictions. First, a large-scale drug knowledge graph is generated from different sources. The knowledge graph is then embedded with comprehensive biomedical text into a common low-dimensional space. Finally, the learned embeddings are used to efficiently compute rich DDI information through a link prediction process.

RESULTS

To validate the effectiveness of the proposed framework, extensive experiments were conducted on real-world data sets. The results demonstrate that our model outperforms several state-of-the-art baseline methods in terms of capability and accuracy.

CONCLUSIONS

We propose a novel framework, Predicting Rich DDI, to predict DDIs. Using rich DDI information, it can competently predict multiple labels for a pair of drugs across numerous domains, ranging from pharmacological mechanisms to side effects. To the best of our knowledge, this framework is the first to provide a joint translation-based embedding model that learns DDIs by integrating drug knowledge graphs and biomedical text simultaneously in a common low-dimensional space. The model also predicts DDIs using multiple labels rather than single or binary labels. Extensive experiments were conducted on real-world data sets to demonstrate the effectiveness and efficiency of the model. The results show our proposed framework outperforms several state-of-the-art baselines.
Effect of Light-Emitting Diodes on the Mycelial Biomass Production and Antioxidant Activity of Ganoderma lucidum (W. Curt.: Fr.) P. Karst.
Authors: Alcazar Abegail , Dulay Rich Milton R. , Kalaw Sofronio , Reyes Renato
Published: March 2021

Light is an important factor for the growth of many forms of life, including mushrooms. This paper highlights the effects of the different wavelengths (red, 650 nm; blue, 450 nm; green, 525 nm) of light emitting diodes (LEDs) on the growth, biomass production and antioxidant properties of Ganoderma lucidum. G. lucidum is a white-rot, wood-degrading fungus in the Basiodiomycota that typically grows on logs. Mycelia were grown on coconut water agar (CWA) solid media for analysis of mycelial colony diameter as well as coconut water (CW) submerged culture for analysis of mycelial biomass weight. Both set-ups were incubated in variously-colored LED chambers. The DPPH radical scavenging activity and total phenolic content of the harvested mycelia were also determined. After three days of incubation, G. lucidum mycelia under red LED recorded the highest mean mycelial colony diameter of 72.50 mm. In terms of mycelia biomass production, G. lucidum mycelia exposed in red LED and dark produced the heaviest weight. On the other hand, mycelia grown under green LED had the highest radical scavenging activity of 66.49% while those harvested from red LED showed the highest total phenolic content of 81.29 mg GAE / g of sample. Our results demonstrate that LED color influences the mycelial growth, biomass production and antioxidant activities of G. lucidum.
Analisa Perbandingan Waktu Pengukuran Menggunakan Kursi Atropometri di Laboratorium Perancangan Sistem Kerja dan Ergonomi UNS
Authors: Sulistyowati Rina
Published: March 2021

Laboratorium Perancangan Sistem Kerja dan Ergonomi (PSKE) Universitas Sebelas Maret Surakarta merupakan laboratorium yang mempunyai dua kursi antropometri untuk kegiatan praktikum dan penelitian yaitu kursi antropometri kayu dan kursi antropometri besi. Setiap semester gasal dilaksanakan praktikum yang melakukan pengukuran dimensi tubuh menggunakan kursi antropometri. Dalam proses pengukuran kedua kursi antropometri mempunyai cara yang berbeda sehingga waktu yang dihasilkan juga berbeda. Untuk mengetahui prosentase perbandingan waktu pengukuran maka dihitung waktu baku yang menggunakan metode perhitungan jam henti.Dari hasil perhitungan waktu baku maka diketahui bahwa kursi antropometri besi memerlukan waktu pengukuran 60% lebih lama dibandingkan dengan kursi antropometri kayu. Hal ini karena ada proses mengangkat kursi antropometri besi waktu lebih lama karena berat dan harus memutar sekrup untuk mengencangkan agar tidak mencederai mahasiswa yang sedang diukur.
Optimalisasi Fungsi Mesin Bubut untuk Proses Pengelasan Rotary Friction Welding Dengan Menambah Jig dan Pendorong Hidrolik
Authors: Sunyoto Sunyoto , Nugraha Gesang , Subarjana Subarjana , Sasmito Agus
Published: March 2021

Mesin bubut adalah mesin yang banyak terdapat di berbagai laboratorium mekanik sekolah menegah maupun perguruan tinggi, yang berfungsi untuk  pembentukan benda kerja logam maupun non logam. Pada penelitian ini dilakukan optimalisasi fungsi mesin bubut dengan penambahan alat bantu jig sebagai penahan gerakan berputar benda kerja di sisi diam dan hidrolik sebagai pendorong arah translasi benda kerja. Penambahan jig dan hidrolik membuat fungsi mesin bubut tidak hanya sebagai alat pembentuk logam namun akan berubah menjadi mesin las gesek untuk menyambung dua bagian benda kerja yang terpisah, dimana mesin bubut standar tidak mampu melakukannya. Penelitian dimulai dari pendataan kondisi mesin bubut, pembuatan disain jig, melakukan produksi jig, uji coba merangkai jig pada mesin bubut, dan terakhir adalah uji pengelasan gesek. Pemilihan material jig dan disain yang tepat akan sangat berpengaruh pada unjuk kerja dan efisiensi jig saat proses pengelasan gesek, dalam penelitian ini proses uji coba dan perbaikan rangkaian jig dilakukan beberapakali sehingga diperoleh disain jig dan penempatan hidrolik pendorong yang tepat. Hasil penelitian ini adalah sebuah rangkaian jig dan hidrolik portable untuk mesin bubut manual, sehingga mampu mengoptimalkan mesin bubut menjadi mesin las gesek. Rangkaian jig ini memiliki kelebihan mudah diproduksi dengan peralatan manual, mudah dibongkar pasang dengan cepat hanya oleh satu orang, mampu menahan getaran dari hasil pengelasan dan kemampuan produksi pengelasan yang cepat. Unjuk kerja Jig ditunjukan dengan hasil pengelasan yang lurus, nilai hasil uji tarik pada spesimen pengelasan  sebesar 10,16 kN mendekati material dasar sebesar 18,97 kN.  Jig hasil penelitian ini juga dapat dengan mudah diaplikasikan pada mesin bubut di laboratorium sekolah menengah, pendidikan tinggi maupun bengkel mekanik yang ada di masyarakat yang memiliki mesin bubut manual.
Bioreduksi Limbah AgNO3 Sisa Proses Pewarnaan Perak Memanfaatkan Eksopolisakarida Bacillus subtilis
Authors: Suharyono Suharyono , Mubarokah Alifah
Published: March 2021

Limbah perak (Ag+) merupakan limbah laboratorium cair yang dihasilkan dari proses pewarnaan perak (silver staining dan immunoblotting). Dalam satu tahun Fakultas Biologi menghasilkan 5-10 liter limbah perak. Limbah ini masih mengandung kadar perak AgNO3 sebanyak 149,5 ppm. Kadar tersebut masih cukup tinggi untuk dimanfaatkan, namun tidak dapat digunakan kembali dalam proses pewarnaan. Pemanfaatan kembali limbah perak dapat dilakukan dengan mengubah partikel perak (Ag+) menjadi nanopartikel-perak (Ag-NPs) melalui proses bioreduksi. Bioreduksi limbah perak dilakukan dengan penambahan eksopolisakarida yang dihasilkan oleh B.subtilis (1:3) selama 52 hari. Nanopartikel-perak yang dihasilkan dimonitoring dengan Spektrofotometer melalui pembentukan kurva plasmon resonans pada panjang gelombang 400-500 nm. Nanopartikel-perak dari proses bioreduksi limbah tersebut mempunyai aktivitas antibakteri secara in-vitro (teknik pour plate) dapat menghambat bakteri e-coli FNCC55 dibandingkan dengan kontrol.
A Non-Blind Robust and Impercept Watermarking Using Discrete Cosine Transform and Discrete Wavelet Transform
Authors: Rachmawanti Eko Hari , Santoso Heru Agus
Published: March 2021

Non-blind watermarking is a form of watermarking with a watermark image validation process that requires a host image. The use of the transform domain is more robust and imperceptible. The transform domain method is resistant to various forms of digital image attacks. In this study, Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT) were selected as watermark insertion algorithms. DCT is faster and more resistant to attacks, especially in image compression attacks, but has lower imperceptibility than DWT. DWT is also known to be resistant to noise attacks, filtering, blurring, cropping, and has high imperceptibility depending on the sub-band selection but is not resistant to image compression attacks. Based on each algorithm's advantages and disadvantages, there is an opportunity to combine it to analyze and compare the insertion results with DCT and DWT itself. To test the results of imperceptibility, we used the Peak Signal to Noise Ratio (PSNR), while to test the robustness, we used Cross-Correlation (CC) and Bit Error Ratio (BER). Without attacks, the PSNR on the proposed method can reach 71 dB. The CC value without attack can reach a perfect value of 1 and BER = 0. The highest attack test result is CC = 1 on the filtering attack. From the various tests we have conducted, it has been proven that the DCT-DWT is more imperceptive and robust than previous studies
A Store-forward Method for Biosignal Acquisition in Smart Health Care System using Wearable IoT Device
Authors: Kartikasari Dany P , Tobing Apriyanto , Bhawiyuga Adhitya , Kusyanti Ari , Purwaningtyas Nuretha Hevy
Published: March 2021

Smart Health Care System has been developed massively in the last decade. Internet of Things implementation has accelerated the development of smart health technology. Now people have realized the importance of doing independent health monitoring. Supported by more affordable e-health tools, motivation in using the smart health system is increasing. The availability of cloud as storage services triggers demands to always be connected to the Internet. However, there are times when interference occurs so the measurement results cannot be stored in the cloud database properly. The idea of using a store-forward mechanism to overcome the problem of disconnected smart healthcare system is proposed in this paper. From the test results, the data can be sent properly eventhough disconnected status occurs for 30 minutes. Smartwatch’s memory usage has increase 30 percent during temporary storage occupied.
Perlindungan Hukum terhadap Hak-Hak Korban dalam Perdagangan Manusia dari Persepektif Hak Asasi Manusia
Authors: Palguna Agus Yogik , Sugiartha I Nyoman Gede , Suryani Luh Putu
Published: March 2021

The crime of trafficking in persons often occurs among women and children. This case is mostly among adult women; this is due to demands (less economic) so that trafficking in persons often occurs. The government must eradicate this case and provide legal protection for victims of trafficking in persons so that women and children are not arbitrarily treated by traffickers. The type of research used is juridical normative; a study the discussion of which is based on laws and legal materials. The results of the analysis show that the criminal sanctions given to the perpetrators must be really sanctions that give a deterrent effect, so that the perpetrators do not repeat their mistakes. In addition, the existence of sanctions can reduce criminal cases of trafficking in persons against women and children, and no one treats women and children arbitrarily, and no longer makes women and children victims of trafficking in persons. So that children and women can become the next generation of the nation to be proud of themselves and others.
Upaya Pencegahan Anak Sebagai Korban Kekerasan Seksual Melalui Dunia Maya
Authors: Linda Saraswati Desak Ketut , Sagung Laksmi Dewi Anak Agung , Minggu Widyantara I Made
Published: March 2021

Since being in the womb, the child has dignity as a whole human being given by God Almighty. A child who is born must get his rights without the child asking. Children who are part of the next generation with the ideals of the nation have a strategic role in ensuring the existence of the nation and state in the future. Sexual violence against children today does not only occur physically but has penetrated cyberspace. This is because it is easy to access cyberspace, especially social media, by various groups ranging from children, adolescents and even parents. This study uses the normative legal method, namely a library research to obtain legal materials. The results of the analysis show that prevention can be done through preventive and repressive measures. Preventive efforts through a family environment that implements the 18-21 program, which means that at 18.00 to 21.00 the time for children and parents to have dialogue and interaction, which was first implemented in Padang City. Besides parents, so that they can give more time and attention to children. Repressive measures are taking action against perpetrators of sexual violence against children through cyberspace in accordance with applicable laws and regulations so that the perpetrators have a deterrent effect and do not repeat it on another day.
Perlindungan Hukum Bagi Pekerja Ud. Alam di Banjar Pendem Kabupaten Jembrana
Authors: Angga Triyadi Giri I Komang Angga Triyadi Giri , Budiartha I Nyoman Putu , Suryani Luh Putu
Published: March 2021

Each person is free to determine the way to earn one's income by being a Labour or Labor building. Each job has its own risk no less quiet work, in order to increase the income source they are ready to spend more time to work to meet the needs of the day and his family. Various fields can make money if diligently lived but sometimes one forgets the safety of himself by working without the use of personal protective equipment. As a well-known company UD, Alam is a company that manufactures daily equipment with wood base material... In its production activities, UD. Nature always uses dangerous tools such as wood cutting tools, chainsaws and other similar tools that are sharp, but until now the workers in UD. Nature still hasn't gained any social security rights as a workforce. In connection with the issue the author conducts research on how the forms of UD responsibilities. Nature of the workers and the factors that are the obstacles of UD. Nature in registering employees to the Occupational Accident Assurance program. This type of research uses empirical law and the type of data used is primary and secondary as well as data collection techniques using the interview techniques and qualitative descriptive data analysis techniques. Protection of UD law. The nature in implementing the accident guarantee is still facing the constraints in the inclusion of workers, in addition to legal awareness of low- business actors is also due to economic factors and technical factors that cause at times workers stop working.
Pertanggungjawaban Pihak Gojek Atas Kerugian yang Diderita Konsumen dalam Hal Penyelenggaraan Pengangkutan Barang
Authors: Adi Putra I Made Pratitha , Putu Budiartha Dr. I Nyoman , Sri Astiti Ni Gusti Ketut
Published: March 2021

Go-Jek phenomenon is an innovation of conventional transport phenomena due to the evidence and/or the transport documents of electronic documents, so it is necessary to  know  how  the  carrier accountability for  losses suffered by consumers (service users) in the carriage of goods by the entrepreneurs of PT. Go-Jek Indonesia and the legal efforts that can be done by consumers. There is a problem in this case 1) how is the transport accountability for losses suffered by consumers (service users) in the carriage of goods by the entrepreneur PT. Go- Jek Indonesia? 2) What is the legal remedy made by the consumer (service user) to the carrier for the losses he suffered?. The method in this research is the type of normative legal research conducted by the recording method and assessment based on the materials of the law. In writing the authors examine and collect information through the books of the law without deviating from the positive laws in  order to  assemble a  conclusion. Mechanisms of  accountability for compensation of consumers because of misconduct of business, PT. Go-Jek Indonesia provides assurance and/or warranty on its services through the terms and conditions that have been listed in the official website that gives a maximum of Rp. 10 million,-. The remedies that can be done by consumers to the carrier for the damage that is suffered is in accordance with the provisions of the Consumer Protection Act,
Tanggung Jawab Hukum terhadap Adanya Wanprestasi dalam Perjanjian Sewa Menyewa Rumah Toko (Ruko)
Authors: Sukayasa I Made , Putu Budiartha I Nyoman , Putu Suryani Luh
Published: March 2021

In various regional areas and cities have done a lot of renewal of buildings with the construction of shophouses. An increasingly developed economic system, the shop houses that have been built can be used as a means of buying and selling. Shophouse is often known as a shop house or residence that is used as a place of business and usually this shophouse is built parallel to other shop houses. The formulation of the problem in this case 1) How is the certainty of the rental agreement to rent a Rumah Toko (Ruko) ?. 2) What is the legal responsibility if one of the parties defaults on the implementation of the lease agreement for a Shophouse? The livelihood of information in a normative study is the method of recording and assessment based on legal sources. In writing this essay the writer examines and collects information through legal science books without deviating from positive law in order to conclude a conclusion. An agreement between the lessee and the owner of the building can bring up the rights and obligations between the parties written in an agreement. Where the renting party has an obligation to claim the rights of the building being rented out to the lessee, and has the right to get paid from the lessee for the rental building. The lessee may not transfer the rights to the building he leases, and if there is a dispute in the future between the parties then it must be resolved because of default.
Penyelesaian Sengketa Pajak Penghasilan (PPH) Pasal 21 Melalui Pengadilan Pajak
Authors: Ina Sulastini Ni Made , Widiat Ida Ayu Putu i , Sutama I Nyoman
Published: March 2021

In the case of taxation obligations, it is not uncommon for tax disputes to occur between the taxpayers and the competent authorities. There are two main problems raised in this study, namely: 1. How is the Tax Court authorized in resolving the tax dispute?, 2. How is the process of resolving income tax disputes article 21 through the Tax Court?. The research methods used in this study are normative legal research methods. Approach to  the  problem used is  the legislation approach. Based on the results of the study indicates that the authority of the Tax Court is resolving tax disputes. The Tax Court in respect of appeals only examines and severes disputes on decision objections, as well as in the event of a tax court lawsuit entitled to inspect and terminate disputes over the implementation of tax collection. In addition to the duties and authorities referred to in article 31, the Tax Court also supervises the legal authority that provides legal aid to the parties to the dispute in the courts of the Tax Court. In the event of an income tax dispute of article 21, the settlement will be done by attempts by law objection if the taxpayer is not satisfied on the decision of the objection then the taxpayer may apply for a legal remedy to the Tax Court . In addition to the appeal remedies that can be submitted to a tax court, taxpayers may also submit a lawsuit.
Importância da inserção de grupo controle em ensaios utilizando animais de laboratório
Authors:   Instituto Nacional de Controle de Qualidade em Saúde (INCQS), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brasil, Simmer Bravin Jussara , Maciel-Magalhães Magno ,   Instituto Nacional de Controle de Qualidade em Saúde (INCQS), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brasil, da Silva Gomes Pinheiro Yasmin ,   Instituto Nacional de Controle de Qualidade em Saúde (INCQS), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brasil, Ângelo Brück Gonçalves Miguel ,   Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brasil, Klabund Ferraris Fausto ,   Instituto Nacional de Controle de Qualidade em Saúde (INCQS), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brasil, Coelho Amendoeira Fábio ,   Instituto Nacional de Controle de Qualidade em Saúde (INCQS), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brasil
Published: March 2021

Introdução: O uso de animais de laboratório é fundamental em áreas em que ainda não podem ser substituídos na totalidade, como a toxicologia. Em estudos que se utilizam, para fins de comparação, apenas dados fornecidos pelos laboratórios de análises clínicas, na tentativa de reduzir o número de animais de um experimento, arrisca-se utilizar informações que não correspondem à realidade. Objetivo: Debater o uso de grupo controle em experimentos com animais. Método: Este artigo comparou valores hematológicos e bioquímicos de ratos da linhagem Wistar, obtidos em três biotérios de criação de diferentes estados brasileiros, com os resultados de animais provindos do Instituto de Ciência e Tecnologia em Biomodelos da Fundação Oswaldo Cruz, Rio de Janeiro, objetivando a discussão acerca da tomada de decisão sobre a inclusão de grupo controle em ensaios de toxicidade aguda oral. Resultados: Poucos foram os parâmetros que não apresentaram diferenças estatísticas, tais como: hemácia em fêmeas (duas referências), hemoglobina em fêmeas (uma referência) e machos (uma referência), hematócrito nos machos (duas referências) e hemoglobina corpuscular média nas fêmeas (duas referências), leucócitos nos machos (uma referência), creatinina e alanina aminotransferase (ALT) em todas as fêmeas. Conclusões: O uso do grupo controle se faz necessário quando valores analisados preliminarmente apresentam-se discrepantes daqueles tidos como referenciais da espécie.
Insumos farmacêuticos ativos irregulares no Brasil: análise descritiva de 2011 a 2019
Authors:   Universidade Federal de São João del-Rei (UFSJ), Divinópolis, MG, Brasil, Naiara Pinto Nubia , Aparecida Resende Karina ,   Universidade Federal de São João del-Rei (UFSJ), Divinópolis, MG, Brasil, Oliveira Couto Renê ,   Universidade Federal de São João del-Rei (UFSJ), Divinópolis, MG, Brasil
Published: March 2021

Introdução: Os insumos farmacêuticos ativos (IFA) correspondem à parte farmacológica do medicamento e a demanda por esses produtos tem gerado grandes lucros para as indústrias farmoquímicas. Por fazerem parte essencial da cadeia produtiva de medicamentos, os IFA estão sujeitos à fiscalização pela Agência Nacional de Vigilância Sanitária (Anvisa) no Brasil. Objetivo: Realizar análise descritiva dos IFA recolhidos no Brasil entre 2011 e 2019, por meio do website da Anvisa na subseção de “produtos irregulares”. Método: Foram obtidos resultados de variáveis denominadas: empresas, motivos, produtos e ações fiscalizadoras. Os resultados foram apresentados como frequências absoluta ou relativa e, dessa forma, traçou-se o perfil descritivo dos insumos irregulares. Resultados: A maioria (80,0%) das empresas com IFA recolhidos é de origem internacional, sendo Índia e China os países predominantes. A frequência de inspeções realizadas pela Anvisa nas empresas apresentou forte correlação com a quantidade de insumos apreendidos (r = 0,89). As principais motivações de recolhimento de IFA são a deficiência nas Boas Práticas de Fabricação (BPF), ausência de registro e contaminação por nitrosaminas. Dos 95 insumos irregulares avaliados, os antimicrobianos e os anti-hipertensivos (antagonistas de angiontensina II) apresentaram as maiores frequências de recolhimentos. Conclusões: A Anvisa está alinhada aos padrões de qualidade de outras agências regulatórias internacionais e tem cumprido com eficiência seu objetivo institucional de garantir e promover a saúde da população brasileira no que concerne à fiscalização de IFA utilizados na produção de medicamentos.