bluuebunny/crossref_metadata_2025 huggingface dataset:
Direct evidence for the source of uranium in the Baiyanghe deposit from accessory mineral alteration in the Yangzhuang granite porphyry, Xinjiang Province, northwest China
Authors: Zhang Long , Li Xiaofeng , Wang Guo , Wang Mou
Published: March 2020

Circumstantial evidence for the sources of uranium in ore deposits may be drawn from the study of deposit geochemistry and mineralogy. However, direct evidence supporting uranium leaching from source rocks has rarely been found. This study investigates the source of uranium in the Baiyanghe deposit in the Xiemisitai Mountains, northwest China. The main uranium ore bodies occur as fracture-fillings along contact zones between the Yangzhuang granite porphyry and the Devonian volcanic rocks. Zircon, thorite, columbite-(Mn), and bastnäsite are the dominant accessory minerals that host uranium in the granite porphyry. In situ columbite-(Mn) LA-ICP-MS U-Pb dating yields a weighted mean 206Pb/238U age of 310 ± 4 Ma, suggesting that the Yangzhuang granite porphyry was emplaced during the Late Carboniferous. Backscattered electron (BSE) images reveal that various degrees of alteration of these same accessory minerals may be observed in the granite porphyry, and the altered domains of these minerals have lower BSE intensities compared to the unaltered domains. Results indicate that the altered domains of zircon grains have lower concentrations of Zr, Si, and U, and higher concentrations of Y, Fe, Ca, and P relative to the unaltered domains, and the altered domains of columbite-(Mn) grains are enriched in Ti and Fe and are depleted in Nb, Ta, Mn, U, and Zr. The altered domains of thorite grains have higher concentrations of Zr, Fe, Ca, Nb, and P, and lower Th and U compared to those of the relict domains. The petrochemical data indicate that the granite porphyry experienced losses in U, Be, F, Ba, Sr, Pb, Zr, Mo, Nb, Ta, and Hf during alteration. These results suggest that the past-magmatic hydrothermal fluids might be responsible for the mobilization of uranium form minerals in the granite porphyry. It is concluded that U-bearing accessory minerals in the granite porphyry were the primary source of uranium, and that post-magmatic hydrothermal processes caused remobilization and significant localized enrichment of the uranium to form high-grade ores as fracture-fillings along its contacts.
A multi-methodological study of kernite, a mineral commodity of boron
Authors: Gatta G. Diego , Guastoni Alessandro , Lotti Paolo , Guastella Giorgio , Fabelo Oscar , Fernandez-Diaz Maria Teresa
Published: March 2020

Kernite, ideally Na2B4O6(OH)2∙3H2O, is a major constituent of borate deposits and one of the most important mineral commodities of B. The chemical composition and crystal structure of kernite from the Kramer Deposit (Kern County, California) were investigated by a suite of analytical techniques (i.e., titrimetric determination of B content, gravimetric method for Na, ion selective electrode for F, high-T mass loss for H2O content, inductively coupled plasma atomic emission spectroscopy for REE and other minor elements, elemental analysis for C, N, and H contents) and single-crystal X-ray (at 293 K) and neutron (at 20 K) diffraction. The concentrations of more than 50 elements were measured. The general experimental formula of the kernite sample used in this study is Na1.99B3.99O6(OH)2∙3.01H2O. The fraction of other elements is, overall, insignificant: excluding B, kernite from the Kramer Deposit does not act as geochemical trap of other technologically relevant elements (e.g., Li, Be, or REE). The X-ray and neutron structure model obtained in this study confirms that the structure of kernite is built up by: two (crystallographically independent) triangular BO2OH groups and two tetrahedral BO4 groups, which share corner-bridging O atoms to form threefold rings, giving chains running along [010], and NaO4(OH)(OH2) and NaO2(OH)(OH2)3 polyhedra. Positional disorder of two H sites of H2O molecules was observed by the neutron structure refinement and corroborated by the maximum-entropy method calculation, which consistently provided a model based on a static disorder, rather than a dynamic one. The H-bonding network in the structure of kernite is complex, pervasive, and plays a primary role on its structural stability: the majority of the oxygen sites are involved in H-bonding, as donors or as acceptors. The potential utilizations of kernite, as a source of B (B2O3 ~50 wt%), are discussed, on the basis of the experimental findings of this study.
Preliminary investigation into the claims of the IBROM system
Authors: Vojdani Zahra , Gorczyca Beata
Published: March 2020

Membrane filtration is commonly applied to reduce dissolved organic carbon (DOC) to control the formation of trihalomethanes (THMs); however, high levels of DOC can cause severe fouling of reverse osmosis membranes. The integrated biological and reverse osmosis membrane (IBROM) process is a combination of biological filters and reverse osmosis membranes. The IBROM process claims to remove biodegradable dissolved organic carbon (BDOC), which apparently should result in reduced membrane fouling. The goal of this research was to conduct a preliminary investigation into the claims of the IBROM system, using water collected from the Herbert water treatment plant (Saskatchewan). The plant is utilizing the IBROM for the treatment of a dugout and groundwater blend (DOC of 17.5–22.7 mg/L). The results demonstrated that BDOC concentrations did not change significantly throughout the plant. Optimized laboratory-scale coagulation with polyaluminium chlorohydrate achieved 58% removal of BDOC. Oxidation with permanganate increased the concentration of BDOC (from 5.7 to 8.8 mg/L). Overall, BDOC was effectively removed by optimized coagulation rather than the IBROM system. Moreover, the results show an inverse relationship between BDOC and THMs formation potential (THMFP) in both coagulated and oxidized water. For all concentrations, more biodegradable DOC had less tendency to form THMs based on the lower THMFP.
Content and Meaning of Nikolai Gogol's Play "The Government Inspector"
Authors: Semenov Igor Vitalievich
Published: March 2020

The article analyzes the content and significance of the wonderful work by Nikolai Vasilyevich Gogol "Revizor". The author of the article draws attention to the relevance of the problems, holds the idea that the main "auditor" is the conscience of man.
Anti-VEGF Treatment in Corneal Diseases
Authors: Giannaccare Giuseppe , Pellegrini Marco , Bovone Cristina , Spena Rossella , Senni Carlotta , Scorcia Vincenzo , Busin Massimo
Published: March 2020

Background:

Corneal neovascularization (CN) is a clue feature of different ocular pathological
conditions and can lead to corneal edema and opacification with subsequent vision loss. Vascular
endothelial growth factor (VEGF), which plays a key role in new vessels formation, proliferation
and migration, was found to be up-regulated in these conditions. Nowadays, it is possible to downregulate
the angiogenic process by using anti-VEGF agents administered by different routes.

Objective:

To evaluate the efficacy, safety and possible future directions of anti-VEGF agents used for
the treatment of CNV owing to different aetiologies.

Methods:

A computerized search of articles dealing with the topic of anti-VEGF therapy in CN was
conducted in PubMed, Scopus and Medline electronic databases. The following key phrases were
used: anti-VEGF agents, corneal neovascularization, bevacizumab, ranibizumab, vascular endothelial
growth factor, angiogenesis.

Results:

The use of anti-VEGF therapy in the treatment of CN reduced pathological vessel density
without causing significant side effects. Various administration routes such as topical, subconjunctival
and intrastromal ones are available, and the choice depends on patient and disease characteristics.
Much more effectiveness is achieved in case of early administration before mature and wellestablished
vessels take place. A combined approach between various drugs including anti-VEGF
agents should be adopted in those cases at higher risk of neovascularization recurrence such as chronic
long-standing diseases where ischemic and inflammatory stimuli are not definitively reversed.

Conclusion:

The efficacy and safety of anti-VEGF agents support their adoption into the daily clinical
practice for the management of CN.
The Antihypertensive, Antimicrobial and Anticancer Peptides from Arthrospira with Therapeutic Potential: A Mini Review
Authors: Montalvo Grecia E. Barriga , Vandenberghe Luciana Porto de Souza , Soccol Vanete Thomaz , Carvalho Júlio Cesar de , Soccol Carlos Ricardo
Published: March 2020

:

The interest in biological peptides from Arthrospira sp. (syn Spirulina) is
increasing due to its Generally Recognised as Safe “GRAS” status, the high
concentration of proteins and the history of its use as a supplement and nutraceutical
agent. Arthrospira peptides can be generated by the controlled hydrolysis of proteins,
using proteases, followed by fractionation. The peptides obtained have a range of
therapeutic effects. Amongst these bioactive peptides, three classes are of major
importance: the antihypertensive (AHP), antimicrobial (AMP) and anticancer (ACP)
peptides. AHPs have the ability to work as inhibitors of angiotensin-converting enzyme
(ACE), and help to control several diseases such as hypertension, obesity, and
cardiovascular issues, AMPs play a crucial role in the immune response, inhibiting the
development of pathogens such as bacteria, fungi, viruses and others, while ACPs can
aid in tumour control by the induction of apoptosis or necrosis, or the inhibition of
angiogenesis. Thus, bioactive peptides are of great significance to the pharmaceutical
industry. However, they can show secondary effects. This paper reviews the inhibition
mechanism of antimicrobial, hypertensive and anticancer peptides from Arthrospira sp.,
and the possible structures of the peptides according to the type of activity and its
intensity. In addition, this paper describes the purification methods of absorption
mechanisms, and reviews databases for designing peptides.
Knockdown of miR-124 Reduces Depression-like Behavior by Targeting CREB1 and BDNF
Authors: Yang Wei , Liu Min , Zhang Qianwei , Zhang Jiahua , Chen Jun , Chen Qiaoyun , Suo Lixia
Published: March 2020

Objective:

As a brain-specific microRNA, the mechanism of miR-124 in depression has
not been clarified so far. The present study aimed to explore the role of miR-124 in depression and
its potential targets.

Methods:

The depression model was first replicated by the chronic unpredictable mild stress
(CUMS) method. miR-124 antagomir was injected into the hippocampus of CUMS rats. Sucrose
preference test (SPT), open-field test (OFT), elevated-plus maze (EPM), and forced swimming test
(FST) were used to analyze the depression-like behavior. The content of norepinephrine (NE), dopamine
(DA) and 5-hydroxytryptamine (5-HT) in the hypothalamus was analyzed by ELISA.
qRT-PCR and western blot assay were used for functional analysis.

Results:

miR-124 expression was up-regulated in the hippocampus of CUMS -induced depression
model rats, while CREB1 and BDNF were down-regulated. Administration of miR-124 antagomir
in the hippocampus inhibited miR-124 expression in the hippocampus of CUMS rats. Additionally,
SPT, OFT, EPM, and FST also showed that miR-124 antagomir can reduce the depression-like
behavior of CUMS rats. Furthermore, miR-124 antagomir injection increased the levels of NE, DA
and 5-HT in the hypothalamus of CUMS rats. Moreover, miR-124 antagomir injection increased
the expression of cyclic AMP-responsive element-binding protein1 (CREB1) and brain-derived
neurotrophic factor (BDNF) in the hippocampus. Using the dual-luciferase reporter assay, it was
confirmed that miR-124 directly targets 3'UTR of CREB1 and BDNF genes.

Conclusion:

Knockdown of miR-124 can improve depression-like behavior in CUMS-induced depressive
rats, which may be related at least in part to the up-regulation of CREB1 and BDNF expression
in the hippocampus.
Recent Trends in Development of Nanomaterials Based Green Analytical Methods for Environmental Remediation
Authors: Amin Sidra , Solangi Amber R. , Hassan Dilawar , Hussain Nadir , Ahmed Jamil , Baksh Hadi
Published: March 2020

Background:

In recent years, the occurrence and fate of environmental pollutants has
been recognized as one of the emerging issues in environmental chemistry. A survey documented a
wide variety of these pollutants, which are often detected in our environment and these are a major
cause of shortened life spans and global warming. These pollutants include toxic metal, pesticides,
fertilizers, drugs, and dyes released into the soil and major water bodies. The presence of these contaminants
causes major disturbance in the balance of the eco-system. To tackle these issues, many
technological improvements are made to detect minute contaminations. The latest issue being answered
by scientists is the use of green nanomaterials as sensors which are economical, instant and
give much better results at low concentrations and can be used for the field measurements resulting
in no dangerous by-product that could lead to more environmental contamination. Nanomaterials are
known for their wide bandgap, enhanced physical, and optical properties with the option of tuneability
as per need, by optimizing certain parameters. They are proved to be a good choice for analytical/
optical sensors with high sensitivity.

Objective:

This review holds information about multiple methods that use green nanomaterials for
the analytical assessment of environmental pollutants. UV-Vis spectrophotometry and electrochemical
analysis using green and reproducible nanomaterials are the major focus of this review article. To
date, there are a number of spectrophotometric and electrochemical methods available that have been
used for the detection of environmental pollutants such as toxic metals, pesticides, and dyes.

Conclusion:

The use of nanomaterials can drastically change the detection limits due to having a
large surface area, strong catalytic properties, and tunable possibility. With the use of nanomaterials,
lower than the marked limit of detection and limit of quantification were seen when compared with
previously reported work. The used nanomaterials could be washed, dried, and reused, which makes
the methods more proficient, cost-effective, and environmentally friendly.
Central Nervous System Depressants and Risk of Hospitalization due to Community-Acquired Pneumonia in very Old Patients
Authors: Espinosa Jeronimo , Alvarez Paulino A. , Castro Veronica , Caceres Maria F. , Soler-Riera Maria C. , Bril Fernando
Published: March 2020

Background:

Central Nervous System (CNS) depressants like antipsychotics, opioids,
benzodiazepines and zolpidem are frequently used by patients of a wide range of ages. Uncertainty
remains about their effect in very old adults (>80 years old) and their potential for pharmacodynamic
and pharmacokinetic drug-drug interactions in this population.

Objective:

To assess if the use of CNS depressants is associated with a higher risk of hospitalization
due to community-acquired pneumonia (CAP) in very old patients.

Methods:

In this prospective study, 362 patients over 80 years of age who had been consequently
admitted to the general ward of a teaching hospital were examined. Each patient was assessed, by
our pharmacovigilance team within 24 hours of admission, to identify outpatient medication use and
potential drug-drug interactions.

Results:

The overall use of CNS depressants as a group was not associated with a higher risk of
admission due to CAP in very old patients (55% vs. 49%; OR=1.28 [0.76-2.16], p=0.34). However,
the use of antipsychotics was associated with a higher rate of admissions due to CAP in this population
(OR=1.98 [1.10-3.57], p=0.02). No association was seen between opioids (p=0.27), zolpidem
(p=0.83), or benzodiazepines (p=0.15) and the rate of admissions due to CAP in these patients.
Moreover, pharmacodynamic or pharmacokinetic interactions leading to CNS depression were
equally found in patients admitted for CAP and those admitted for other reasons.

Conclusion:

The use of antipsychotics in very old adults was associated with an increased risk of
hospital admission due to CAP. This suggests that the use of these medications in this population
should be done with caution. No association was observed with opioids, benzodiazepines and
zolpidem with the latter outcome.
Behavioral Evaluation of the Effects of Aqueous and Ethanol Extracts of Suaeda vermiculata Forssk on Rats
Authors: Mohammed Hamdoon A.
Published: March 2020

Background:

Suaeda vermiculata is one of the widely distributed halophytes in central
Saudi Arabia. The plant is used as a remedy for liver diseases, jaundice, and inflammation. S.
vermiculata is also used as camels' food by local shepherds.

Purpose:

The study aims to evaluate the behavioral antidepressant and anxiolytic effects of S.
vermiculata aqueous and ethanol extracts.

Methods:

Aqueous and ethanol extracts of S. vermiculata were prepared by the maceration technique.
Standard forced swim test cylinder and light/dark chamber device were used to evaluate the
antidepressant and anxiolytic activities of the extracts (200 mg/kg) in rats model, respectively.

Results:

The aqueous and ethanol extracts of S. vermiculata showed remarkable antidepressant
activity with significant increase in the swimming time and reduced immobility in the rats compared
to imipramine treated animals (P<0.05). Ethanol extract increased the swimming time by
20% and decreased the immobility time by more than 60% compared to the control group of animals.
In contrast, the extracts induced the anxiety behavior in experimental rats compared to vehicle-
treated animals. The extracts significantly (P<0.001) reduced the time spent by rats in the
light chamber by more than 50% and increased the time spent in dark chamber as compared with
the control group and the group receiving diazepam.

Conclusion:

The medicinally important plant S. vermiculata induced anxiety behavior with antidepressant
activity in rats. These effects from our point of view are similar to the effects of some
common beverages containing caffeine such as coffee and tea.
Satisfaction with Singlehood in Never-Married Singles: The Role of Gender and Culture
Authors: Ochnik Dominika , Slonim Gal
Published: March 2020

Aim:

The aim of this study was to reveal the role of gender and culture (German vs Polish) in Satisfaction With Singlehood (SWS).

Background:

Due to the number of singles increasing over the past decades, the assessment of the extent to which such people are satisfied with their singlehood and establishment of specific variables enabling satisfaction with life in singlehood to be predicted seem valid. An additional factor was gender and culture, as feminine and masculine roles are defined mainly by familial and matrimonial life and diverse cultural context.

Methods:

Study 1 encompassed 512 never married childless singles above 30 years old, Study 2: 196 Polish never-married singles, and Study 3: 265 German never-married singles (pairfam data).

Research methods were: Satisfaction with singlehood, Multidimensional Sexuality Questionnaire (MSQ), Inventory of Gender Assessment (IPP), Multidimensional Self-Esteem Inventory (MSEI), UCLA III Loneliness Scale, Romantic Beliefs Scale (RBS), Interpersonal Competences Questionnaire (ICQ), Satisfaction with Life Scale (SWLS). German sample was retrieved from The German Panel Analysis of Intimate Relationships and Family Dynamics – pairfam.

Results:

Study 1 revealed significant medium effects of gender and country, with women and German sample reporting a higher SWS. Study 2 showed different prediction models for Polish sample. SWS was explained by satisfaction with life, romantic belief, loneliness, and competence in women. The predictors in Polish men were: initiating relationships and internal sexual control. Study 3 revealed willingness to have a partner as the only predictor in German women, and in German men: satisfaction with life, loneliness and mating confidence.

Conclusion:

Satisfaction With Singlehood (SWS) was higher in women than men, regardless of culture. German single never-married women were the most satisfied group. Traditional masculine role predicted higher SWS in single men. Satisfaction with singlehood proved to be separate from satisfaction with life.
DESIGN AND DISCOURSE OF MODERN STANDARD ARABIC E-TEXTBOOK
Authors: Thohir Muhammad , Kurjum Mohammad , Muhid Abdul
Published: March 2020

An E-textbook of Modern Standard Arabic (MSA) is an important device that supports the on-line practical aspects of the teaching Arabic as a foreign language (TAFL). The present study was aimed at describing the characteristics of the design and discourse of the Schulz’s E-textbooks of MSA. The study focused on Schulz MSA E-Textbook as an instructional material package of standard Arabic of the intermediate levels (B1 and B2 levels). The study used the qualitative research approach with the discourse-analysis method of data analyses.The results showed the following findings. The design of the E-package is web-based with multimedia as resources. The content prioritizes on grammar material in each initial lesson unit of the textbook. Although standard modern Arabic is used as the language variant for the language skills, colloquial language variants are given sufficient attention that can be accessed only in the E-edition version of the package. In terms of the contents of the discourse, a wide selection of texts are used with varied themes in the field of education, social affairs, economy, culture,  politics,  religion, environment,  and technology. Citations embedded in header texts do not always match the contents of the discourse. The religious discourse pieces in the materials seem to be positioned more as socio-cultural facts rather than as theological facts. Keywords: E-textbook, Modern Standard Arabic, discourse, learning material  DESAIN DAN WACANA BUKU PELAJARAN BAHASA ARAB BAKU AbstrakBuku ajar elektronik bahasa Arab standar merupakan perangkat penting yang mendukung aspek-aspek praktis online pada pembelajaran bahasa Arab sebagai bahasa asing (PBABA). Penelitian ini bertujuan untuk menggambarkan karakteristik desain dan muatan wacana buku ajar elektronik bahasa Arab Standar. Kajian difokuskan pada e-text karya Eckehard Schulz yang banyak digunakan di Indonesia dan dibatasi pada tingkat menengah (tingkat B1-B2). Penelitian menggunakan pendekatan penelitian deskriptif kualitatif dengan analisis wacana. Hasil penelitian menunjukkan temuan berikut. Desain e-textbook MSA Schulz berkarakter web based dengan multimedia sebagai resources. Kontennya memprioritaskan materi tata bahasa di setiap awal pelajaran. Meskipun keterampilan berbahasa Arab ditekankan pada penggunaan variasi standar atau modern language, variasi colloquial language mendapat perhatian cukup memadai yang hanya dapat diakses dalam versi e-edition. Dari segi muatan wacana, ia menghadirkan banyak muatan seperti pendidikan, sosial, ekonomi, budaya, politik, agama, lingkungan, dan teknologi. Kutipan yang disematkan di setiap header halaman tidak selalu cocok dengan isi wacana. Yang menarik, wacana agama di dalamnya terlihat lebih diposisikan sebagai fakta sosial-budaya daripada fakta teologis. Kata kunci: buku elektronik, bahasa Arab standar, wacana, kegiatan pembelajaran
TRANSLATION PROCEDURES AND IDEOLOGY OF TWO DIFFERENT ENGLISH TRANSLATION VERSIONS OF SURAH AL-FATIHAH: A CONTRASTIVE ANALYSIS
Authors: Sukarno Sukarno , Adilia Risyah , Setiarini Riskia
Published: March 2020

English translation of the Holy Qur’an comes as solutions for Muslims and non-Muslims worldwide to be able to understand the message of the Holy Qur’an besides its authentic Arabic text. Two of the most famous versions are translated by Saheeh International SI (2004) and Abdel Haleem hereafter AH (2004). Since Arabic and English belong to different language families, the translations resulted in the variation of lexicons and grammatical structures to express the same meaning in English from the Holy Qur’an. This research attempts to reveal how lexical and grammatical differences happened in two different English translation versions of surah al-Fatihah by SI and AH. The data were analyzed using a contrastive analysis method with content analysis. The results showed that firstly, there are lexical and grammatical differences in the five ayats. Secondly, SI used procedures that are mostly oriented to the SLT such as transcription and componential analysis while AH used procedures that are mostly oriented to the TLT such as modulation and contraction. Lastly, the two translators applied different dominant ideologies on their translations. SI represents the foreignization ideology while AH represents domestication ideology. Keywords: al-Fatihah, English translation, contrastive analysis, translation procedures, translation ideology PROSEDUR PENERJEMAHAN DAN IDEOLOGI DALAM DUA VERSI  TERJEMAHAN BAHASA INGGRIS SURAT AL-FATIHAH:  SEBUAH ANALISIS KONTRASTIF AbstrakTerjemahan bahasa Inggris dari kitab suci AlQur’an adalah sebuah solusi untuk orang-orang muslim dan nonmuslim di seluruh dunia untuk dapat memahami isi dari kitab suci AlQur’an di samping teks Arab aslinya. Di antara versi terjemahan-terjemahan kitab suci AlQur’an, dua yang paling terkenal diterjemahkan oleh Saheeh International yang disingkat SI (2004) dan Abdel Haleem (2004) yang disingkat AH. Karena bahasa Arab dan bahasa Inggris berasal dari keluarga bahasa yang berbeda, terdapat beberapa perbedaan leksikal dan gramatikal dalam terjemahan dari kitab suci Al-Qur’an untuk menunjukkan makna yang sama di dalam bahasa Inggris. Penelitian ini bertujuan untuk mengkaji bagaimana perbedaan leksikal dan gramatikal terjadi pada dua versi terjemahan surah al-Fatihah oleh SI dan AH. Data dianalisis menggunakan metode analisis kontrastif dengan analisis konten. Hasil penelitian menunjukkan bahwa pertama, terdapat perbedaan leksikal dan gramatikal yang dapat ditemukan di 5 ayat. Kedua, SI menggunakan prosedur yang kebanyakan berorientasi pada bahasa sumber seperti transkripsi dan analisis komponen, sedangkan AH menggunakan prosedur yang kebanyakan berorientasi pada bahasa sasaran seperti modulasi dan reduksi. Selain itu, SI cenderung menggunakan ideologi foreignisasi, sedangkan AH cenderung menggunakan ideologi domestikasi. Kata kunci: Al-Fatihah, terjemahan bahasa Inggris, analisis kontrastif, prosedur penerjemahan, ideologi penerjemahan
Autoencoder as a New Method for Maintaining Data Privacy While Analyzing Videos of Patients With Motor Dysfunction: Proof-of-Concept Study
Authors: D'Souza Marcus , Van Munster Caspar E P , Dorn Jonas F , Dorier Alexis , Kamm Christian P , Steinheimer Saskia , Dahlke Frank , Uitdehaag Bernard M J , Kappos Ludwig , Johnson Matthew
Published: March 2020

Background

In chronic neurological diseases, especially in multiple sclerosis (MS), clinical assessment of motor dysfunction is crucial to monitor the disease in patients. Traditional scales are not sensitive enough to detect slight changes. Video recordings of patient performance are more accurate and increase the reliability of severity ratings. When these recordings are automated, quantitative disability assessments by machine learning algorithms can be created. Creation of these algorithms involves non–health care professionals, which is a challenge for maintaining data privacy. However, autoencoders can address this issue.

Objective

The aim of this proof-of-concept study was to test whether coded frame vectors of autoencoders contain relevant information for analyzing videos of the motor performance of patients with MS.

Methods

In this study, 20 pre-rated videos of patients performing the finger-to-nose test were recorded. An autoencoder created encoded frame vectors from the original videos and decoded the videos again. The original and decoded videos were shown to 10 neurologists at an academic MS center in Basel, Switzerland. The neurologists tested whether the 200 videos were human-readable after decoding and rated the severity grade of each original and decoded video according to the Neurostatus-Expanded Disability Status Scale definitions of limb ataxia. Furthermore, the neurologists tested whether ratings were equivalent between the original and decoded videos.

Results

In total, 172 of 200 (86.0%) videos were of sufficient quality to be ratable. The intrarater agreement between the original and decoded videos was 0.317 (Cohen weighted kappa). The average difference in the ratings between the original and decoded videos was 0.26, in which the original videos were rated as more severe. The interrater agreement between the original videos was 0.459 and that between the decoded videos was 0.302. The agreement was higher when no deficits or very severe deficits were present.

Conclusions

The vast majority of videos (172/200, 86.0%) decoded by the autoencoder contained clinically relevant information and had fair intrarater agreement with the original videos. Autoencoders are a potential method for enabling the use of patient videos while preserving data privacy, especially when non–health-care professionals are involved.
A Graph Convolutional Network–Based Method for Chemical-Protein Interaction Extraction: Algorithm Development
Authors: Wang Erniu , Wang Fan , Yang Zhihao , Wang Lei , Zhang Yin , Lin Hongfei , Wang Jian
Published: March 2020

Background

Extracting the interactions between chemicals and proteins from the biomedical literature is important for many biomedical tasks such as drug discovery, medicine precision, and knowledge graph construction. Several computational methods have been proposed for automatic chemical-protein interaction (CPI) extraction. However, the majority of these proposed models cannot effectively learn semantic and syntactic information from complex sentences in biomedical texts.

Objective

To relieve this problem, we propose a method to effectively encode syntactic information from long text for CPI extraction.

Methods

Since syntactic information can be captured from dependency graphs, graph convolutional networks (GCNs) have recently drawn increasing attention in natural language processing. To investigate the performance of a GCN on CPI extraction, this paper proposes a novel GCN-based model. The model can effectively capture sequential information and long-range syntactic relations between words by using the dependency structure of input sentences.

Results

We evaluated our model on the ChemProt corpus released by BioCreative VI; it achieved an F-score of 65.17%, which is 1.07% higher than that of the state-of-the-art system proposed by Peng et al. As indicated by the significance test (P<.001), the improvement is significant. It indicates that our model is effective in extracting CPIs. The GCN-based model can better capture the semantic and syntactic information of the sentence compared to other models, therefore alleviating the problems associated with the complexity of biomedical literature.

Conclusions

Our model can obtain more information from the dependency graph than previously proposed models. Experimental results suggest that it is competitive to state-of-the-art methods and significantly outperforms other methods on the ChemProt corpus, which is the benchmark data set for CPI extraction.
Rancang Bangun Computer Vision System (CVS) Sebagai Instrumen Pengukuran Warna Buah-Buahan
Authors: Simanungkalit Ferlando Jubelito , Simanjuntak Rosnawyta
Published: March 2020

Color had a correlation with physical appearance, nutritional and chemical content as well as sensory properties which determine the quality of agricultural products and foods. Conventional color measurements were performed destructively using laboratory equipment. Therefore, color measurement methods of agricultural products were needed more quickly, accurately and non-destructively. This study aimed to develop a Computer Vision System (CVS) that can be used as a tool to measure the color of fruits. The designed CVS consists of a 60x60x60 cm black mini photo studio; a pair 15 watt LED lighting, sony α6000 digital camera, a set of laptop and an image processing software applications. Image processing software was programmed using VB.Net 2008 programming language. The developed CVS was calibrated using 24 color charts Macbeth Colorchecker (Gretag-Macbeth, USA). The calibration results of 24 color chart of Macbeth Colorchecker was resulted in a MAPE (Mean Absolute Percentage Error) value of component R / Red = 0%; G / Green = 0% and B / Blue = 0,5%; with 99% accuracy rate. In color measurement, the developed CVS had a 95% accuracy rate.
La muerte sin escena
Authors: Schnait Nelly
Published: March 2020

La muerte sin escena
"No me interrumpas": las mujeres y el ensayo latinoamericano
Authors: Pratt Mary Louise
Published: March 2020

"No me interrumpas": las mujeres y el ensayo latinoamericano
Ética y feminismo
Authors: Serret Estela
Published: March 2020

Ética y feminismo
Configuración sociosimbólica del celibato femenino
Authors: Fioretti Susana
Published: March 2020

Configuración sociosimbólica del celibato femenino
Doméstica, mujer o hija de familia: identidades en entredicho
Authors: Goldsmith Mary
Published: March 2020

Doméstica, mujer o hija de familia: identidades en entredicho
Trabajo doméstico
Authors: Moreno Hortensia
Published: March 2020

Trabajo doméstico
Cuando el 'mejor interés del niño 'es la peor política
Authors: Gordon Linda
Published: March 2020

Cuando el 'mejor interés del niño 'es la peor política
Un nuevo movimiento social
Authors: Sánchez Jorge Alonso
Published: March 2020

Un nuevo movimiento social
Lo inconfesable, Io obsceno, el detalle
Authors: Mendiola Salvador
Published: March 2020

Lo inconfesable, Io obsceno, el detalle
El mito del orgasmo vaginal
Authors: Koedt Anne , Ramos Mingo Daniela
Published: March 2020

El mito del orgasmo vaginal
Poemas
Authors: Bracho Coral
Published: March 2020

Poemas
Sobre la memoria
Authors: Lorenzano Sandra
Published: March 2020

Sobre la memoria
La tecnología del orgasmo
Authors: Maines P. Rachel , Mansour Mónica
Published: March 2020

La tecnología del orgasmo
El vaciamiento del sujeto y el regreso del racismo
Authors: Barcellona Pietro , González Pont Juan Carlos , Silveira Gorski Héctor Claudio
Published: March 2020

El vaciamiento del sujeto y el regreso del racismo
Derechos sexuales ¿parte del ordenamiento jurídico?, entrevista con el Dr. José Luis Soberanes Fernández
Authors: Hernández Forcada Ricardo
Published: March 2020

Derechos sexuales ¿parte del ordenamiento jurídico?, entrevista con el Dr. José Luis Soberanes Fernández
Bibi, ¿qué hiciste?
Authors: Peled Nurit , Moheno Rubén
Published: March 2020

Bibi, ¿qué hiciste?
Por qué voté en contra de la guerra
Authors: Lee Barbara , Olivares Cecilia
Published: March 2020

Por qué voté en contra de la guerra
A favor de Ia disidencia: entrevista a Susan Sontag
Authors: Talbot David , Olivares Cecilia
Published: March 2020

A favor de Ia disidencia: entrevista a Susan Sontag
Cuando la dignidad ofende a un régimen: acerca del asesinato de Digna Ochoa
Authors: Gutiérrez Aguilar Raquel
Published: March 2020

Cuando la dignidad ofende a un régimen: acerca del asesinato de Digna Ochoa
Malas palabras
Authors: Rodríguez Jesusa
Published: March 2020

Malas palabras
Las oprimidas sospechadas. La desconfianza hacia las mujeres sin conciencia de género: un recaudo feminista contra los estragos del control patriarcal
Authors: Hercovich Inés
Published: March 2020

Las oprimidas sospechadas. La desconfianza hacia las mujeres sin conciencia de género: un recaudo feminista contra los estragos del control patriarcal
Juego de pelota: metáforas visuales
Authors: González Lucero , Lorenzano Sandra
Published: March 2020

Juego de pelota: metáforas visuales
Big Mother: el gran desmadre
Authors: Gasé Marisol , Huerta Nora , Francis Mor Ana , Sotres Cecilia , Rodríguez Jesusa
Published: March 2020

Big Mother: el gran desmadre
¡Que vivan las mujeres!
Authors: Felipe Liliana , Orozco Regina , Rodríguez Jesusa
Published: March 2020

¡Que vivan las mujeres!
"Sólo ignorancia" detrás del proyecto de abstinencia sexual del gobierno de George Bush
Authors: Villamil Jenaro
Published: March 2020

Sólo ignorancia detrás del proyecto de abstinencia sexual del gobierno de George Bush
Sobre aborto y políticas públicas
Authors: Ubaldi Garcete Norma
Published: March 2020

Sobre aborto y políticas públicas
Del arrebato al espanto: la inteligencia perversa en Apariciones de Margo Glantz
Authors: Álvarez Enid
Published: March 2020

Del arrebato al espanto: la inteligencia perversa en Apariciones de Margo Glantz
Ella no era una mujer, era una...
Authors: Lorenzano Sandra
Published: March 2020

Ella no era una mujer, era una...
Las chavas y el grafiti hip hop
Authors: Chillys Willys Chorcha , Hernández Gloria , Hernández Reyes María Adela , Mendiola Salvador
Published: March 2020

Las chavas y el grafiti hip hop
Los Legionarios de Cristo
Authors: Tarrés María Luisa
Published: March 2020

Los Legionarios de Cristo
Pastorela extraterrestre
Authors: Arroyo Tizoc , Gasé Marisol , Huerta Nora , Rodríguez Jesusa , Sotres Cecilia
Published: March 2020

Pastorela extraterrestre
Política en imágenes
Authors: Alcaraz Lorena
Published: March 2020

Política en imágenes
El duelo, entre la antropología y el psicoanálisis
Authors: Colin Araceli
Published: March 2020

El duelo, entre la antropología y el psicoanálisis
Resistir
Authors: Sontag Susan , Major Aurelio
Published: March 2020

Resistir
Los nombres de la Rosa
Authors: López Vigil María
Published: March 2020

Los nombres de la Rosa
Lo imposible sólo tarda un poco más
Authors: Robles Raquel
Published: March 2020

Lo imposible sólo tarda un poco más
Sólo cólera
Authors: Phillips Adam , Bernal Gloria Elena
Published: March 2020

Sólo cólera
Para ubicar el género
Authors: Gutmann Matthew C.
Published: March 2020

Para ubicar el género
Foximiliano y Martota
Authors: Rodríguez Jesusa
Published: March 2020

Foximiliano y Martota
Y si la historia (337)
Authors: Felipe Liliana , Rodríguez Jesusa
Published: March 2020

Y si la historia (337)
Desnaturalizando la nación autoritaria: una propuesta queer
Authors: Novoa Adriana , Szurmuk Mónica
Published: March 2020

Desnaturalizando la nación autoritaria: una propuesta queer
De sexilio(s) y diáspora(s) homosexual(es) Iatina(s): cultura puertorriqueña y lo nuyorican queer
Authors: La Fountain-Stokes Lawrence
Published: March 2020

De sexilio(s) y diáspora(s) homosexual(es) latina(s): cultura puertorriqueña y lo nuyorican queer
Crímenes de odio en Estados Unidos. La distinción analitica entre excluir y discriminar
Authors: Mercedes Gómez María
Published: March 2020

Crímenes de odio en Estados Unidos. La distinción analitica entre excluir y discriminar
Laberintos del amor y el sacrificio en La Traviata
Authors: Gerez Ambertín Marta
Published: March 2020

Laberintos del amor y el sacrificio en La Traviata
Las solteronas de Eld
Authors: Selzer Richard , Moreno Hortensia
Published: March 2020

Las solteronas de Eld
Las yeguas finas: una etnografía novelada
Authors: Belausteguigoitia Marisa
Published: March 2020

Las yeguas finas: una etnografía novelada
Foro "Ni madres"
Authors: Feminista Debate
Published: March 2020

Foro "Ni madres"
En el nombre de una madre
Authors: Teresa Priego María
Published: March 2020

En el nombre de una madre
A mi madre
Authors: Rodríguez Jesusa
Published: March 2020

A mi madre
¡Qué melocotones y qué penumbras!
Authors: Álvarez Enid
Published: March 2020

¡Qué melocotones y qué penumbras!
Club de enemigos de Fox (Un espectáculo sobre la desobediencia civil)
Authors: Rodríguez Jesusa , Victoria Simone
Published: March 2020

Club de enemigos de Fox
Fallamos como especie
Authors: Felipe Liliana
Published: March 2020

Fallamos como especie
Sexo fuerte
Authors: Osorio Teresa
Published: March 2020

Mujeres movidas
Discurso del presidente del gobierno español, José Luis Rodríguez Zapatero, en el pleno del Congreso de los diputados para defender las modificación del código civil que reconoce el derecho a contraer matrimonio a personas del mismo sexo
Authors: Rodríguez Zapatero José Luis
Published: March 2020

Discurso en el pleno del Congreso
Las discusiones actuales de la teoría feminista
Authors: Dietz Mary , Olivares Mansuy Cecilia
Published: March 2020

Discusiones actuales de la teoría feminista
La inconformista : Elfriede Jelinek en nueve pausas
Authors: Rivera-Garza Cristina
Published: March 2020

La inconformista : Elfriede Jelinek en nueve pausas
La boda
Authors: Rodríguez Jesusa
Published: March 2020

La boda
Adopción transnacional: robo de criaturas, familias homoparentales y neoliberalismo
Authors: Briggs Laura , Bernal Gloria Elena
Published: March 2020

Adopción transnacional: robo de criaturas, familias homoparentales y neoliberalismo
Pereza/diligencia. La franja de sombra
Authors: Lavín Mónica
Published: March 2020

Pereza/diligencia. La franja de sombra
Avaricia/generosidad. La avaricia y sus soledades
Authors: Moreno Hortensia
Published: March 2020

Avaricia/generosidad. La avaricia y sus soledades
Envidia/solidaridad. Política interna
Authors: Enrique Álvaro
Published: March 2020

Envidia/solidaridad. Política interna
La otra frontera capital vida/muerte. Suicidio: notas sin sosiego
Authors: Kraus Arnoldo
Published: March 2020

La otra frontera capital vida/muerte. Suicidio: notas sin sosiego
¿Hay libertad después de Roe? Cómo pensar acerca del feto
Authors: Kissling Frances , Benton Erika
Published: March 2020

¿Hay libertad después de Roe? Cómo pensar acerca del feto
Una demanda ciudadana: la despenalización en Uruguay
Authors: Carbajal Mariana
Published: March 2020

Una demanda ciudadana: la despenalización en Uruguay
La situación del aborto en la Argentina. Un debate pendiente
Authors: Carbajal Mariana
Published: March 2020

La situación del aborto en la Argentina. Un debate pendiente
Nicaragua: el aborto en la batalla electoral del 2006
Authors: Montenegro Sofía
Published: March 2020

Nicaragua: el aborto en la batalla electoral del 2006
El acceso al aborto por violación en la Ciudad de México: limitaciones, oportunidades y desafíos
Authors: Ubaldi Garcete Norma
Published: March 2020

El acceso al aborto por violación en la Ciudad de México: limitaciones, oportunidades y desafíos
Elena Garro (1916-1998)
Authors: Melgar Lucía
Published: March 2020

Elena Garro (1916-1998)
¿Por qué hacer psicoanálisis?
Authors: Sánchez Guadarrama Beatriz
Published: March 2020

¿Por qué hacer psicoanálisis?
"Let us be the healing wound": escribiendo desde la herida
Authors: Joysmith Claire
Published: March 2020

"Let us be the healing wound": escribiendo desde la herida
El derecho a estar sola
Authors: Riley Denise , Golubov Nattie , Olivares Cecilia
Published: March 2020

El derecho a estar sola
Fabricado en China
Authors: Hilton Isabel , Cruz Eva
Published: March 2020

Fabricado en China
La situación laboral y sindical de las mujeres en la maquiladora de México
Authors: Quintero Cirila
Published: March 2020

La situación laboral y sindical de las mujeres en la maquiladora de México
Transformar el dolor en fuerza positiva. Conversación con Michelle Bachelet
Authors: Wood María Elena
Published: March 2020

Transformar el dolor en fuerza positiva
Esencial y desesperada. Una entrevista con Idea Vilariño
Authors: Poniatowska Elena
Published: March 2020

Esencial y desesperada. Una entrevista con Idea Vilariño
Feminismo y modernidad
Authors: Guzmán Virginia , Bonan Claudia
Published: March 2020

Feminismo y modernidad
Carta a mis amigas y amigos
Authors: D'Artigues Katia
Published: March 2020

Carta a mis amigas y amigos
El lenguaje del placer
Authors: Amuchástegui Herrera Ana
Published: March 2020

El lenguaje del placer
Me hubiera gustado vivir del futbol
Authors: Osorio Teresa , Moreno Hortensia
Published: March 2020

Me hubiera gustado vivir del futbol
El cuerpo en la calle. Crónicas fragmentarias
Authors: Melgar Lucía
Published: March 2020

El cuerpo en la calle. Crónicas fragmentarias
Mujeres y hombres en la UNAM
Authors: Moreno Hortensia
Published: March 2020

Mujeres y hombres en la UNAM
El silencio del sexo
Authors: Hernández Gloria , Hernández Reyes María Adela , Mendiola Salvador
Published: March 2020

El silencio del sexo
El testamento de Frida Kahlo
Authors: Rodríguez Jesusa
Published: March 2020

El testamento de Frida Kahlo
Fotografías
Authors: Kupferminc Mirta
Published: March 2020

Fotografías
La violación: un arma de guerra
Authors: Franco Jean
Published: March 2020

La violación: un arma de guerra
El recuento. Algunas exploraciones a la obra de Kiki Smith
Authors: Mallet Ana Elena
Published: March 2020

El recuento. Algunas exploraciones a la obra de Kiki Smith
Effi Briest, una mujer insoportable
Authors: Bercovich Susana
Published: March 2020

Effi Briest, una mujer insoportable
Ella no es una voz que se ahoga
Authors: Navalón Antonio
Published: March 2020

Ella no es una voz que se ahoga
La despenalización de aborto en la Ciudad de México
Authors: Reproducción Elegida Grupo de Información En
Published: March 2020

La despenalización de aborto en la Ciudad de México
Lecciones de lógica: a partir de la serie Satori de Magali Lara
Authors: Cordero Karen
Published: March 2020

Lecciones de lógica: a partir de la serie Satori de Magali Lara
El tatuaje de Simón
Authors: Guerrero McManus Fabrizzio
Published: March 2020

El tatuaje de Simón
Simone de Beauvoir y el terror a la vejez
Authors: Poniatowska Elena
Published: March 2020

Simone de Beauvoir y el terror a la vejez
Funeral de Doña Jesusa Ramírez Gama
Authors: Rodríguez Jesusa
Published: March 2020

Funeral de Doña Jesusa Ramírez Gama
La visibilidad internacional es un escudo para los periodistas amenazados
Authors: Iglesias Kuntz Lucía
Published: March 2020

La visibilidad internacional es un escudo para los periodistas amenazados
Modificaciones en materia de reasignación sexo-genérica
Authors: Jefatura de Gobierno Administración Pública Del Distrito Federal
Published: March 2020

Modificaciones en materia de reasignación sexo-genérica
Palabras de agradecimiento
Authors: Loria Cecilia
Published: March 2020

Palabras de agradecimiento
La crítica feminista como modelo de crítica cultural
Authors: Richard Nelly
Published: March 2020

La crítica feminista como modelo de crítica cultural
Preguntas no respondidas
Authors: Scott Joan
Published: March 2020

Preguntas no respondidas
Género y performance. 3 episodios de un cybermanga feminista queer trans...
Authors: Preciado Beatriz
Published: March 2020

Género y performance.  3 episodios de un cybermanga feminista queer trans...
Vocabularios en resistencia
Authors: Martínez de la Escalera Ana María
Published: March 2020

Vocabularios en resistencia
La cruzada antiaborto
Authors: Woldenberg Jose
Published: March 2020

La cruzada antiaborto
¿Qué encuentro se busca? Breves cavilaciones sobre el XI Encuentro Feminista Latinoamericano y de El Caribe
Authors: Bartra Eli
Published: March 2020

¿Qué encuentro se busca? Breves cavilaciones sobre el XI Encuentro Feminista Latinoamericano y de El Caribe
Apuntes para un balance de la expresión del feminismo en la región y México
Authors: Socialistas Feministas
Published: March 2020

Apuntes para un balance de la expresión del feminismo en la región y México
Louise Bourgeois: víctima y asesina
Authors: Navarrete Sylvia
Published: March 2020

Louise Bourgeois: víctima y asesina
Yo soy muy dada a ver lo positivo
Authors: Rius Pilar
Published: March 2020

Yo soy muy dada a ver lo positivo
Prodigio de la fotografía
Authors: Acevedo Marta
Published: March 2020

Prodigio de la fotografía
Envejecimiento: una asignatura pendiente
Authors: Cardaci Dora
Published: March 2020

Envejecimiento: una asignatura pendiente
Darle un número a las diferencias
Authors: Parrini Rodrigo
Published: March 2020

Darle un número a las diferencias
Discriminación y victimización: marcha del orgullo LGBT en Chile
Authors: Barrientos Jaime
Published: March 2020

Discriminación y victimización: marcha del orgullo LGBT en Chile
Interpretar "la protección de la vida"
Authors: Cook Rebecca , Molinari Tato Ariadna
Published: March 2020

Interpretar "la protección de la vida"
Fin a una década de criminalización por aborto contra mujeres pobres en Guanajuato
Authors: Cruz Sánchez Verónica
Published: March 2020

Fin a una década de criminalización por aborto contra mujeres pobres en Guanajuato
Más libres
Authors: Madrazo Lajous Alejandro
Published: March 2020

Más libres