bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from The Human TLR Innate Immune Gene Family Is Differentially Influenced by DNA Stress and p53 Status in Cancer Cells
Authors: Shatz Maria , Menendez Daniel , Resnick Michael A.
Published: March 2023

PDF file - 150K, Dose response of TLR induction to genotoxic stress
Supplementary Figure 1 from Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth
Authors: Prudent Renaud , Vassal-Stermann Emilie , Nguyen Chi-Hung , Pillet Catherine , Martinez Anne , Prunier Chloé , Barette Caroline , Soleilhac Emmanuelle , Filhol Odile , Beghin Anne , Valdameri Glaucio , Honoré Stéphane , Aci-Sèche Samia , Grierson David , Antonipillai Juliana , Li Rong , Di Pietro Attilio , Dumontet Charles , Braguer Diane , Florent Jean-Claude , Knapp Stefan , Bernard Ora , Lafanechère Laurence
Published: March 2023

PDF file - 212K, Effect of Pyr1 treatment on the number and on the size of EB1 comets in HeLa cells
Supplementary Figure 8 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 180K, Effect of RKIP expression on B-RAF mutant cells
Supplementary Figure 9 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 143K
Supplementary Figure 1 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 35K
Supplementary Figure 3 from Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis
Authors: Park Serk In , Liao Jinhui , Berry Janice E. , Li Xin , Koh Amy J. , Michalski Megan E. , Eber Matthew R. , Soki Fabiana N. , Sadler David , Sud Sudha , Tisdelle Sandra , Daignault Stephanie D. , Nemeth Jeffrey A. , Snyder Linda A. , Wronski Thomas J. , Pienta Kenneth J. , McCauley Laurie K.
Published: March 2023

PDF file - 129K, Cyclophosphamide suppressed PC-3 prostate tumor growth in the tibiae
Supplementary Figure 6 from HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem–like Cells
Authors: Nishizawa Satoshi , Hirohashi Yoshihiko , Torigoe Toshihiko , Takahashi Akari , Tamura Yasuaki , Mori Takashi , Kanaseki Takayuki , Kamiguchi Kenjiro , Asanuma Hiroko , Morita Rena , Sokolovskaya Alice , Matsuzaki Junichi , Yamada Ren , Fujii Reona , Kampinga Harm H. , Kondo Toru , Hasegawa Tadashi , Hara Isao , Sato Noriyuki
Published: March 2023

PDF file - 92K, Serine-rich region of DNAJB8 has role for induction of SP cells
Supplementary Figure 4 from HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem–like Cells
Authors: Nishizawa Satoshi , Hirohashi Yoshihiko , Torigoe Toshihiko , Takahashi Akari , Tamura Yasuaki , Mori Takashi , Kanaseki Takayuki , Kamiguchi Kenjiro , Asanuma Hiroko , Morita Rena , Sokolovskaya Alice , Matsuzaki Junichi , Yamada Ren , Fujii Reona , Kampinga Harm H. , Kondo Toru , Hasegawa Tadashi , Hara Isao , Sato Noriyuki
Published: March 2023

PDF file - 67K, Western blot analysis
Supplementary Methods and Materials and Figure Legends from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file-166K
Supplementary Figure 2 from HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem–like Cells
Authors: Nishizawa Satoshi , Hirohashi Yoshihiko , Torigoe Toshihiko , Takahashi Akari , Tamura Yasuaki , Mori Takashi , Kanaseki Takayuki , Kamiguchi Kenjiro , Asanuma Hiroko , Morita Rena , Sokolovskaya Alice , Matsuzaki Junichi , Yamada Ren , Fujii Reona , Kampinga Harm H. , Kondo Toru , Hasegawa Tadashi , Hara Isao , Sato Noriyuki
Published: March 2023

PDF file - 74K, RT-PCR analysis
Supplementary Figure 9 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 1.8 MB, Cytokine profile of CD11b+ Gr-1int cells.
Supplementary Figure 8 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 1781 K, CD11b+ Gr-1int cells do not suppress or enhance NK cell cytotoxic function.
Supplementary Figure 2 from Therapeutic Administration of a Synthetic CpG Oligodeoxynucleotide Triggers Formation of Anti-CpG Antibodies
Authors: Karbach Julia , Neumann Antje , Wahle Claudia , Brand Kathrin , Gnjatic Sacha , Jäger Elke
Published: March 2023

PDF file - 48K, Analysis of circulating immune complexes using standard ELISA CIC-C1q (based on interaction of CICs with complement) and CIC-C3d (Raji cell assay based on C3d binding)
Supplementary Figure 4 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 806K, Host NLRP3 does not affect B16F10 subcutaneous growth.
Supplementary Tables 1-2 from Metastatic Cells Can Escape the Proapoptotic Effects of TNF-α through Increased Autocrine IL-6/STAT3 Signaling
Authors: Li Shun , Wang Ni , Brodt Pnina
Published: March 2023

PDF file - 74K
Supplementary Methods from p53 Inhibits Angiogenesis by Inducing the Production of Arresten
Authors: Assadian Sarah , El-Assaad Wissal , Wang Xue Q.D. , Gannon Phillipe O. , Barrès Véronique , Latour Mathieu , Mes-Masson Anne-Marie , Saad Fred , Sado Yoshikazu , Dostie Josée , Teodoro Jose G.
Published: March 2023

PDF file - 158K
Supplementary Table 5 from Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors
Authors: Walker Erin J. , Zhang Cindy , Castelo-Branco Pedro , Hawkins Cynthia , Wilson Wes , Zhukova Nataliya , Alon Noa , Novokmet Ana , Baskin Berivan , Ray Peter , Knobbe Christiane , Dirks Peter , Taylor Michael D. , Croul Sidney , Malkin David , Tabori Uri
Published: March 2023

PDF file - 69K
Supplementary Table 3 from Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors
Authors: Walker Erin J. , Zhang Cindy , Castelo-Branco Pedro , Hawkins Cynthia , Wilson Wes , Zhukova Nataliya , Alon Noa , Novokmet Ana , Baskin Berivan , Ray Peter , Knobbe Christiane , Dirks Peter , Taylor Michael D. , Croul Sidney , Malkin David , Tabori Uri
Published: March 2023

PDF file - 74K
Supplementary Figures 1-8, Video Legends 1-3 from Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages
Authors: Movahedi Kiavash , Schoonooghe Steve , Laoui Damya , Houbracken Isabelle , Waelput Wim , Breckpot Karine , Bouwens Luc , Lahoutte Tony , De Baetselier Patrick , Raes Geert , Devoogdt Nick , Van Ginderachter Jo A.
Published: March 2023

PDF file - 1.7MB, This file contain Supplementary figures 1 to 8. Supplementary Figure 1: MMR expression on distinct cell types present in s.c. TS/A and 3LL-R tumor suspensions. Supplementary Figure 2: Anti-MMR differentially labels TAM subsets in s.c. TS/A tumor sections Supplementary Figure 3. SPR competition studies with anti-MMR Nbs cl1 and cl3 on immobilized mouse MMR protein Supplementary Figure 4. Anti-MMR Nb cl1 binding to distinct cell types in liver single-cell suspensions Supplementary Figure 5. TAM subpopulations from 3LL-R tumors grown s.c. in MMR-KO mice. Supplementary Figure 6. Flow cytometric analyses of WT and CCR2-KO s.c. 3LL-R tumors. Supplementary Figure 7. Effect of mono- and bivalent anti-MMR Nb on immune cell activation in vitro. Supplementary Figure 8. Effect of mono- and bivalent anti-MMR Nb on immune cell activation in vivo
Supplementary Figure 7 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 120K, The relative expression of CCL5 receptors in human breast cancer cell lines and the Jurkat cell line
Supplementary Figure Legends 1-3 from Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Authors: Ramkumar Charusheila , Kong Yahui , Cui Hang , Hao Suyang , Jones Stephen N. , Gerstein Rachel M. , Zhang Hong
Published: March 2023

PDF file - 60K
Supplementary Figure Legends 1-4 from Fra-1 Promotes Breast Cancer Chemosensitivity by Driving Cancer Stem Cells from Dormancy
Authors: Lu Dan , Chen Si , Tan Xiaoyue , Li Na , Liu Chenghu , Li Zongjin , Liu Ze , Stupack Dwayne G. , Reisfeld Ralph A. , Xiang Rong
Published: March 2023

PDF file - 56K
Supplementary Figure 4 from Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Authors: Ramkumar Charusheila , Kong Yahui , Cui Hang , Hao Suyang , Jones Stephen N. , Gerstein Rachel M. , Zhang Hong
Published: March 2023

PDF file - 290K, Hematoxylin & Eosin and B220 staining of paraffin-embedded sections of lymphomas found in spleens of Smurf2T/T (T/T) and Smurf2+/T (+/T) mice. Scale bar: 100 mu
Supplementary Figure 2 from Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Authors: Ramkumar Charusheila , Kong Yahui , Cui Hang , Hao Suyang , Jones Stephen N. , Gerstein Rachel M. , Zhang Hong
Published: March 2023

PDF file - 241K, Hematoxylin & Eosin staining of tissues from 2-month old wild-type (+/+) and Smurf2T/T (T/T) mice shows a normal development of Smurf2-deficient mice. Scale bars are 200 mu for 10X images and 100 mu for 50X images.
Supplementary Methods, Tables 1-2 from Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
Authors: Hu Rong , Lu Changxue , Mostaghel Elahe A. , Yegnasubramanian Srinivasan , Gurel Meltem , Tannahill Clare , Edwards Joanne , Isaacs William B. , Nelson Peter S. , Bluemn Eric , Plymate Stephen R. , Luo Jun
Published: March 2023

PDF file - 100K, Supplemental Table 1. Expression correlation of AR and AR-V to selected AR target genes in LuCaP xenografts. Supplemental Table II. Protein expression levels in 67 CRPC TMA specimens
Supplementary Table 1 from Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
Authors: Friedlander Terence W. , Roy Ritu , Tomlins Scott A. , Ngo Vy T. , Kobayashi Yasuko , Azameera Aruna , Rubin Mark A. , Pienta Kenneth J. , Chinnaiyan Arul , Ittmann Michael M. , Ryan Charles J. , Paris Pamela L.
Published: March 2023

XLS file - 15K, Candidate Gene List and Copy number:Expression Correlation for Frequently Aberrant Genes.
Supplementary Figure 5 from Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression
Authors: Sisirak Vanja , Faget Julien , Gobert Michael , Goutagny Nadège , Vey Nelly , Treilleux Isabelle , Renaudineau Sarah , Poyet Gaelle , Labidi-Galy Sana Intidhar , Goddard-Leon Sophie , Durand Isabelle , Le Mercier Isabelle , Bajard Agathe , Bachelot Thomas , Puisieux Alain , Puisieux Isabelle , Blay Jean-Yves , Ménétrier-Caux Christine , Caux Christophe , Bendriss-Vermare Nathalie
Published: March 2023

PDF file, 72K, FACS analysis of CD40, CD80, and CD86 on TApDC following 40 h-culture in IL-3 alone or in combination with flu, R848, CpG-A, and CpG-B.
Supplementary Figure 4 from Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression
Authors: Sisirak Vanja , Faget Julien , Gobert Michael , Goutagny Nadège , Vey Nelly , Treilleux Isabelle , Renaudineau Sarah , Poyet Gaelle , Labidi-Galy Sana Intidhar , Goddard-Leon Sophie , Durand Isabelle , Le Mercier Isabelle , Bajard Agathe , Bachelot Thomas , Puisieux Alain , Puisieux Isabelle , Blay Jean-Yves , Ménétrier-Caux Christine , Caux Christophe , Bendriss-Vermare Nathalie
Published: March 2023

PDF file, 768K, IHC analysis on frozen BT sections was performed using anti-BDCA2 (brown) together with anti-CD3 (green, a) or anti- cytokeratine (green, b) antibodies (x10)
Supplementary Table 4 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
Authors: Bai Yun , Li Jiannong , Fang Bin , Edwards Arthur , Zhang Guolin , Bui Marilyn , Eschrich Steven , Altiok Soner , Koomen John , Haura Eric B.
Published: March 2023

PDF file - 42K, Characteristics of primary xenograft human sarcoma tissues
Supplementary Figure 3 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
Authors: Bai Yun , Li Jiannong , Fang Bin , Edwards Arthur , Zhang Guolin , Bui Marilyn , Eschrich Steven , Altiok Soner , Koomen John , Haura Eric B.
Published: March 2023

PDF file - 78K, Effects of BMS754807 on cell proliferation in sarcoma cell lines
Supplementary Figure 1 from Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma
Authors: Wondergem Bill , Zhang Zhongfa , Huang Dachuan , Ong Choon Kiat , Koeman Julie , Hof David Van't , Petillo David , Ooi Aikseng , Anema John , Lane Brian , Kahnoski Richard J. , Furge Kyle A. , Teh Bin Tean
Published: March 2023

PDF file, 251K, Supplemental Figure S1 (a) Gene expression profiling of 131 clinical specimens for which we have staging information shows that overexpression of PTTG1 correlates with high tumor stage. (b) Association of increased PTTG1 expression with decreased probability of survival for 5-years. Dashed lines indicate 95% confidence intervals (c) Similarly, ECT2 overexpression is most prominent in high stage ccRCC tumors. (d) PTTG1 and ECT2 are coordinately overexpressed in primarily high stage tumors. (e) Cells completely deficient of ECT2 acquire a highly-branched and spindle-shaped morphology.
Supplementary Table 4 from Kidney Tumor Biomarkers Revealed by Simultaneous Multiple Matrix Metabolomics Analysis
Authors: Ganti Sheila , Taylor Sandra L. , Abu Aboud Omran , Yang Joy , Evans Christopher , Osier Michael V. , Alexander Danny C. , Kim Kyoungmi , Weiss Robert H.
Published: March 2023

XLS file - 56K, Variable Importance in Projection (VIP) data for Tissue, Serum and Urine
Supplementary Figure 1 from Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Authors: Sceneay Jaclyn , Chow Melvyn T. , Chen Anna , Halse Heloise M. , Wong Christina S.F. , Andrews Daniel M. , Sloan Erica K. , Parker Belinda S. , Bowtell David D. , Smyth Mark J. , Möller Andreas
Published: March 2023

PDF file - 296K, A)Regulation of Hif-1� and Hif-2alpha by hypoxia in breast cancer cells. B) Schematic of injection schedule
Supplementary Figure 1 from Antigen Shedding May Improve Efficiencies for Delivery of Antibody-Based Anticancer Agents in Solid Tumors
Authors: Pak Youngshang , Zhang Yujian , Pastan Ira , Lee Byungkook
Published: March 2023

PDF file - 343K, A schematic of RIT intracellular trafficking pathways
Supplementary Figures 1-2, Gene Data from Hedgehog and Notch Signaling Regulate Self-Renewal of Undifferentiated Pleomorphic Sarcomas
Authors: Wang Chang Ye Yale , Wei Qingxia , Han Ilkyu , Sato Shingo , Azarnier Ronak Ghanbari- , Whetstone Heather , Poon Raymond , Hu Jiayi , Zheng Feifei , Zhang Phil , Wang Weishi , Wunder Jay S. , Alman Benjamin A.
Published: March 2023

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Supplementary Figure 2 from Accumulation of Multipotent Progenitors with a Basal Differentiation Bias during Aging of Human Mammary Epithelia
Authors: Garbe James C. , Pepin Francois , Pelissier Fanny A. , Sputova Klara , Fridriksdottir Agla J. , Guo Diana E. , Villadsen Rene , Park Morag , Petersen Ole W. , Borowsky Alexander D. , Stampfer Martha R. , LaBarge Mark A.
Published: March 2023

PDF file - 972K, Analysis of HMEC lineages in strains derived from reduction mammoplasty (RM) versus peripheral non-tumor regions from mastectomy (P) tissues
Supplementary Table 1 from Viral RNA Patterns and High Viral Load Reliably Define Oropharynx Carcinomas with Active HPV16 Involvement
Authors: Holzinger Dana , Schmitt Markus , Dyckhoff Gerhard , Benner Axel , Pawlita Michael , Bosch Franz X.
Published: March 2023

PDF file - 57K, Table S1. Integrated Prediction Error (5 years range of integration). To estimate the prediction error we used the .632+ estimate of the integrated Brier score. For OS the cumulative prediction error decreased from 0.192 for the model with clinical factors to 0.182 using additional HPV marker combination and to 0.183 using additional CxCa-like viral RNA patterns. On the contrary, no improvement in prediction accuracy was observed for PFS by adding single HPV markers or marker combinations to clinical factors.
Supplementary Figure 1 from Viral RNA Patterns and High Viral Load Reliably Define Oropharynx Carcinomas with Active HPV16 Involvement
Authors: Holzinger Dana , Schmitt Markus , Dyckhoff Gerhard , Benner Axel , Pawlita Michael , Bosch Franz X.
Published: March 2023

PDF file - 447K, Figure S1. Examples of immunohistochemical staining patterns of p16INK4a in OPSCC. A, typical HPV16 driven OPSCC (CxCaRNA+) with high p16INK4a; B, discordant HPV16 driven OPSCC with low p16INK4a (note staining in stroma); C, typical HPV16-negative OPSCC with low p16INK4a (HPV-); D, discordant HPV16-negative OPSCC with high p16INK4a. Original magnification 100-times. T, tumor; S, stroma.
Supplementary Figure Legends 1-5 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Authors: Liu Xiyong , Lai Lily , Wang Xiaochen , Xue Lijun , Leora Sofia , Wu Jun , Hu Shuya , Zhang Keqiang , Kuo Mei-Ling , Zhou Lun , Zhang Hang , Wang Yafan , Wang Yan , Zhou Bingsen , Nelson Rebecca A. , Zheng Shu , Zhang Suzhan , Chu Peiguo , Yen Yun
Published: March 2023

Supplementary Figure Legends 1-5 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Supplementary Figure 3 from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa
Authors: Ng Yi-Zhen , Pourreyron Celine , Salas-Alanis Julio C. , Dayal Jasbani H.S. , Cepeda-Valdes Rodrigo , Yan Wenfei , Wright Sheila , Chen Mei , Fine Jo-David , Hogg Fiona J. , McGrath John A. , Murrell Dedee F. , Leigh Irene M. , Lane E. Birgit , South Andrew P.
Published: March 2023

PDF file - 409K, Invasion of SCCRDEB4 keratinocytes into RDEB cell derived matrix is increased after 1 week compared with equivalent non-RDEB cell derived matrix. Representative images from pan-keratin stained images of 1-week invasion of tumor cells into fibroblast derived matrix. Magnification 200X.
Supplementary Figure 2 from FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy
Authors: Li Zhoulei , Graf Nicolas , Herrmann Ken , Jünger Alexandra , Aichler Michaela , Feuchtinger Annette , Baumgart Anja , Walch Axel , Peschel Christian , Schwaiger Markus , Buck Andreas , Keller Ulrich , Dechow Tobias
Published: March 2023

PDF file - 51K, Effect of everolimus on SUDHL-1 cells in vitro
Supplementary Figure 2 from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa
Authors: Ng Yi-Zhen , Pourreyron Celine , Salas-Alanis Julio C. , Dayal Jasbani H.S. , Cepeda-Valdes Rodrigo , Yan Wenfei , Wright Sheila , Chen Mei , Fine Jo-David , Hogg Fiona J. , McGrath John A. , Murrell Dedee F. , Leigh Irene M. , Lane E. Birgit , South Andrew P.
Published: March 2023

PDF file - 190K, A: RDEBSCCF derived matrix promotes adhesion of keratinocytes compared with matrix derived from other fibroblast groups (* = p<0.01). All data normalized to collagen I adhesion, results are the mean of three separate experiments performed in quintuplicate �SD, n=3-5 per fibroblast sample group. B-E: Keratinocyte adhesion to cell derived matrix from the indicated fibroblast samples. Each graph combines the results from up to three experiments for each keratinocyte group as indicated, mean �SD performed in quintuplicate. NHK = immortalized normal keratinocyte lines (NHK38 spontaneous immortalized foreskin, Thai5 HPV immortalized axilla), UVSCCK = spontaneously immortalized UV cSCC keratinocytes (6), RDEBK = HPV immortalized RDEB keratinocytes, RDEBSCCK = spontaneously immortalized RDEB cSCC keratinocytes (6). Fibroblast sample details are given in Supplementary Data Table 1.
Supplementary Figure 3 from Clusterin Mediates TGF-β–Induced Epithelial–Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer Cells
Authors: Shiota Masaki , Zardan Anousheh , Takeuchi Ario , Kumano Masafumi , Beraldi Eliana , Naito Seiji , Zoubeidi Amina , Gleave Martin E.
Published: March 2023

PDF file - 48K, PC-3 cells were transfected with 40 nmol/L of the indicated siRNA. At 48 h after transfection, the media was changed to serum-free media +/- 0.1 ng/mL TGF-beta, and incubated for 24 h. Whole-cell extracts were analyzed by SDS-PAGE and western blot analysis with specified antibodies
Supplementary Figure 2 from Clusterin Mediates TGF-β–Induced Epithelial–Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer Cells
Authors: Shiota Masaki , Zardan Anousheh , Takeuchi Ario , Kumano Masafumi , Beraldi Eliana , Naito Seiji , Zoubeidi Amina , Gleave Martin E.
Published: March 2023

PDF file - 38K, PC-3 cells were transfected with 0.5 mug/mL of the CLU-Luc -1,998/+254, 0.5 mug/mL of the indicated expression plasmid, and 0.05 mug/mL of pRL-TK. The luciferase activity of CLU-Luc -1,998/+254 with mock plasmid (Myc-Flag) was set as 1. Boxes, mean; bars, �s.d. *P < 0.05 (compared with mock). Whole-cell extracts were analyzed by SDS-PAGE and western blot analysis with specified antibodies
Supplementary Table 2 from Identification of an Epigenetic Profile Classifier That Is Associated with Survival in Head and Neck Cancer
Authors: Poage Graham M. , Butler Rondi A. , Houseman E. Andrés , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Marsit Carmen J. , Kelsey Karl T.
Published: March 2023

XLS file - 566K, Differentially-methylated CpG Loci In Each Patient Methylation Subgroup
Supplementary Tables 1-13 from 19p13.1 Is a Triple-Negative–Specific Breast Cancer Susceptibility Locus
Authors: Stevens Kristen N. , Fredericksen Zachary , Vachon Celine M. , Wang Xianshu , Margolin Sara , Lindblom Annika , Nevanlinna Heli , Greco Dario , Aittomäki Kristiina , Blomqvist Carl , Chang-Claude Jenny , Vrieling Alina , Flesch-Janys Dieter , Sinn Hans-Peter , Wang-Gohrke Shan , Nickels Stefan , Brauch Hiltrud , Ko Yon-Dschun , Fischer Hans-Peter , Schmutzler Rita K. , Meindl Alfons , Bartram Claus R. , Schott Sarah , Engel Christoph , Godwin Andrew K. , Weaver JoEllen , Pathak Harsh B. , Sharma Priyanka , Brenner Hermann , Müller Heiko , Arndt Volker , Stegmaier Christa , Miron Penelope , Yannoukakos Drakoulis , Stavropoulou Alexandra , Fountzilas George , Gogas Helen J. , Swann Ruth , Dwek Miriam , Perkins Annie , Milne Roger L. , Benítez Javier , Zamora María Pilar , Pérez José Ignacio Arias , Bojesen Stig E. , Nielsen Sune F. , Nordestgaard Børge G. , Flyger Henrik , Guénel Pascal , Truong Thérèse , Menegaux Florence , Cordina-Duverger Emilie , Burwinkel Barbara , Marmé Frederick , Schneeweiss Andreas , Sohn Christof , Sawyer Elinor , Tomlinson Ian , Kerin Michael J. , Peto Julian , Johnson Nichola , Fletcher Olivia , dos Santos Silva Isabel , Fasching Peter A. , Beckmann Matthias W. , Hartmann Arndt , Ekici Arif B. , Lophatananon Artitaya , Muir Kenneth , Puttawibul Puttisak , Wiangnon Surapon , Schmidt Marjanka K. , Broeks Annegien , Braaf Linde M. , Rosenberg Efraim H. , Hopper John L. , Apicella Carmel , Park Daniel J. , Southey Melissa C. , Swerdlow Anthony J. , Ashworth Alan , Orr Nicholas , Schoemaker Minouk J. , Anton-Culver Hoda , Ziogas Argyrios , Bernstein Leslie , Dur Christina Clarke , Shen Chen-Yang , Yu Jyh-Cherng , Hsu Huan-Ming , Hsiung Chia-Ni , Hamann Ute , Dünnebier Thomas , Rüdiger Thomas , Ulmer Hans Ulrich , Pharoah Paul P. , Dunning Alison M. , Humphreys Manjeet K. , Wang Qin , Cox Angela , Cross Simon S. , Reed Malcom W. , Hall Per , Czene Kamila , Ambrosone Christine B. , Ademuyiwa Foluso , Hwang Helena , Eccles Diana M. , Garcia-Closas Montserrat , Figueroa Jonine D. , Sherman Mark E. , Lissowska Jolanta , Devilee Peter , Seynaeve Caroline , Tollenaar Rob A.E.M. , Hooning Maartje J. , Andrulis Irene L. , Knight Julia A. , Glendon Gord , Mulligan Anna Marie , Winqvist Robert , Pylkäs Katri , Jukkola-Vuorinen Arja , Grip Mervi , John Esther M. , Miron Alexander , Alnæs Grethe Grenaker , Kristensen Vessela , Børresen-Dale Anne-Lise , Giles Graham G. , Baglietto Laura , McLean Catriona A. , Severi Gianluca , Kosel Matthew L. , Pankratz V.S. , Slager Susan , Olson Janet E. , Radice Paolo , Peterlongo Paolo , Manoukian Siranoush , Barile Monica , Lambrechts Diether , Hatse Sigrid , Dieudonne Anne-Sophie , Christiaens Marie-Rose , Chenevix-Trench Georgia , Beesley Jonathan , Chen Xiaoqing , Mannermaa Arto , Kosma Veli-Matti , Hartikainen Jaana M. , Soini Ylermi , Easton Douglas F. , Couch Fergus J.
Published: March 2023

PDF file - 272K
Supplementary Figure 1 from Identification of an Epigenetic Profile Classifier That Is Associated with Survival in Head and Neck Cancer
Authors: Poage Graham M. , Butler Rondi A. , Houseman E. Andrés , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Marsit Carmen J. , Kelsey Karl T.
Published: March 2023

PDF file - 51K, Frequency histogram outlining the methylation characteristics of the study population
Supplementary Table 4 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: March 2023

PDF file - 54K
Supplementary Table 3 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: March 2023

PDF file - 54K
Supplementary Table 1 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: March 2023

PDF file - 55K
Supplementary Methods from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: March 2023

PDF file - 82K
Supplementary Figure 1 from Targeting eNOS in Pancreatic Cancer
Authors: Lampson Benjamin L. , Kendall S. DiSean , Ancrile Brooke B. , Morrison Meghan M. , Shealy Michael J. , Barrientos Katharine S. , Crowe Matthew S. , Kashatus David F. , White Rebekah R. , Gurley Susan B. , Cardona Diana M. , Counter Christopher M.
Published: March 2023

PDF file - 243K, eNOS is upregulated in human pancreatic cancers
Supplementary Figures 1-4, Tables 1-3 from Leptin Mediates Tumor–Stromal Interactions That Promote the Invasive Growth of Breast Cancer Cells
Authors: Barone Ines , Catalano Stefania , Gelsomino Luca , Marsico Stefania , Giordano Cinzia , Panza Salvatore , Bonofiglio Daniela , Bossi Gianluca , Covington Kyle R. , Fuqua Suzanne A.W. , Andò Sebastiano
Published: March 2023

PDF file - 285K
Supplementary Table 7 from Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model
Authors: Floc'h Nicolas , Kinkade Carolyn Waugh , Kobayashi Takashi , Aytes Alvaro , Lefebvre Celine , Mitrofanova Antonina , Cardiff Robert D. , Califano Andrea , Shen Michael M. , Abate-Shen Cory
Published: March 2023

DOC file, 347K, GSEA data for the castrated mice.
Supplementary Figure Legend from RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Authors: Wang Hongyan , Liu Kaihua , Geng Miao , Gao Peng , Wu Xiaoyuan , Hai Yan , Li Yangxia , Li Yulong , Luo Lin , Hayes John D. , Wang Xiu Jun , Tang Xiuwen
Published: March 2023

PDF file - 120K
Supplementary Figure 6 from RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Authors: Wang Hongyan , Liu Kaihua , Geng Miao , Gao Peng , Wu Xiaoyuan , Hai Yan , Li Yangxia , Li Yulong , Luo Lin , Hayes John D. , Wang Xiu Jun , Tang Xiuwen
Published: March 2023

PDF file - 239K, The interaction of mNrf2 with RXRa in MCF7-RXRa cells.
Supplementary Figure 1 from RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Authors: Wang Hongyan , Liu Kaihua , Geng Miao , Gao Peng , Wu Xiaoyuan , Hai Yan , Li Yangxia , Li Yulong , Luo Lin , Hayes John D. , Wang Xiu Jun , Tang Xiuwen
Published: March 2023

PDF file - 499K, Recombinant his-RXRa was unable to interact with GST-hNRF2 mutant fusion protein that lacked residues 209-316 between the Neh5 and Neh6 domains.
Supplementary Materials & Methods from MEK1/2 Inhibition Decreases Lactate in BRAF-Driven Human Cancer Cells
Authors: Falck Miniotis Maria , Arunan Vaitha , Eykyn Thomas R. , Marais Richard , Workman Paul , Leach Martin O. , Beloueche-Babari Mounia
Published: March 2023

Supplementary Materials & Methods - PDF file 73K, Supplementary Materials & Methods
Supplementary Figure 3 from CDK1 Regulates Mediator of DNA Damage Checkpoint 1 during Mitotic DNA Damage
Authors: Yu Bing , Dalton W. Brian , Yang Vincent W.
Published: March 2023

PDF file - 64K, Mitotic indices of cells
Supplementary Table Legends 1-2 from Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
Authors: Richards Juliet , Lim Ai Chiin , Hay Colin W. , Taylor Angela E. , Wingate Anna , Nowakowska Karolina , Pezaro Carmel , Carreira Suzanne , Goodall Jane , Arlt Wiebke , McEwan Iain J. , de Bono Johann S. , Attard Gerhardt
Published: March 2023

PDF file - 42K
Supplementary Figure Legends 1-7 from Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
Authors: Richards Juliet , Lim Ai Chiin , Hay Colin W. , Taylor Angela E. , Wingate Anna , Nowakowska Karolina , Pezaro Carmel , Carreira Suzanne , Goodall Jane , Arlt Wiebke , McEwan Iain J. , de Bono Johann S. , Attard Gerhardt
Published: March 2023

PDF file - 55K
Supplementary Figure 5 from Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
Authors: Richards Juliet , Lim Ai Chiin , Hay Colin W. , Taylor Angela E. , Wingate Anna , Nowakowska Karolina , Pezaro Carmel , Carreira Suzanne , Goodall Jane , Arlt Wiebke , McEwan Iain J. , de Bono Johann S. , Attard Gerhardt
Published: March 2023

PDF file - 106K
Supplementary Figure 2 from Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
Authors: Richards Juliet , Lim Ai Chiin , Hay Colin W. , Taylor Angela E. , Wingate Anna , Nowakowska Karolina , Pezaro Carmel , Carreira Suzanne , Goodall Jane , Arlt Wiebke , McEwan Iain J. , de Bono Johann S. , Attard Gerhardt
Published: March 2023

PDF file - 212K
Supplementary Figure 1 from Oxidative Stress-Regulated Lentiviral TK/GCV Gene Therapy for Lung Cancer Treatment
Authors: Leinonen Hanna M. , Ruotsalainen Anna-Kaisa , Määttä Ann-Marie , Laitinen Heidi M. , Kuosmanen Suvi M. , Kansanen Emilia , Pikkarainen Jere T. , Lappalainen Jari P. , Samaranayake Haritha , Lesch Hanna P. , Kaikkonen Minna U. , Ylä-Herttuala Seppo , Levonen Anna-Liisa
Published: March 2023

PDF file - 324K, The effect of ganciclovir and doxorubicin on ARE activity
Supplementary Tables 4-5 from Polyploidization of Murine Mesenchymal Cells Is Associated with Suppression of the Long Noncoding RNA H19 and Reduced Tumorigenicity
Authors: Shoshani Ofer , Massalha Hassan , Shani Nir , Kagan Sivan , Ravid Orly , Madar Shalom , Trakhtenbrot Luba , Leshkowitz Dena , Rechavi Gideon , Zipori Dov
Published: March 2023

PDF file - 38K, Lists of MSC populations and clones used in the study, their origin, ploidy and tumorigenic incidence
Supplementary Legends for Figures 1-8, Tables 1-5 from Polyploidization of Murine Mesenchymal Cells Is Associated with Suppression of the Long Noncoding RNA H19 and Reduced Tumorigenicity
Authors: Shoshani Ofer , Massalha Hassan , Shani Nir , Kagan Sivan , Ravid Orly , Madar Shalom , Trakhtenbrot Luba , Leshkowitz Dena , Rechavi Gideon , Zipori Dov
Published: March 2023

PDF file - 89K
Supplementary Figure 4 from Glutamine Deprivation Enhances Antitumor Activity of 3-Bromopyruvate through the Stabilization of Monocarboxylate Transporter-1
Authors: Cardaci Simone , Rizza Salvatore , Filomeni Giuseppe , Bernardini Roberta , Bertocchi Fabio , Mattei Maurizio , Paci Maurizio , Rotilio Giuseppe , Ciriolo Maria Rosa
Published: March 2023

PDF file - 55K, Increased oxidative stress underlies 3-BrPA chemo-potentiation induced by glutamine-deprivation
Supplementary Materials and Methods from NF-κB Activity Regulates Mesenchymal Stem Cell Accumulation at Tumor Sites
Authors: Uchibori Ryosuke , Tsukahara Tomonori , Mizuguchi Hiroyuki , Saga Yasushi , Urabe Masashi , Mizukami Hiroaki , Kume Akihiro , Ozawa Keiya
Published: March 2023

PDF file - 104K
Supplementary Table 3 from Genetic Polymorphisms and Protein Expression of NRF2 and Sulfiredoxin Predict Survival Outcomes in Breast Cancer
Authors: Hartikainen Jaana M. , Tengström Maria , Kosma Veli-Matti , Kinnula Vuokko L. , Mannermaa Arto , Soini Ylermi
Published: March 2023

PDF file - 68K, Association between NRF2 and SRXN1 protein expression
Supplementary Figures 2-8 from Genetic Polymorphisms and Protein Expression of NRF2 and Sulfiredoxin Predict Survival Outcomes in Breast Cancer
Authors: Hartikainen Jaana M. , Tengström Maria , Kosma Veli-Matti , Kinnula Vuokko L. , Mannermaa Arto , Soini Ylermi
Published: March 2023

PDF file - 1.2MB, Survival curves for breast cancer survival according to NRF2 and SRXN1 genotypes and protein expression
Supplementary Text from SENP1 deSUMOylates and Regulates Pin1 Protein Activity and Cellular Function
Authors: Chen Chun-Hau , Chang Che-Chang , Lee Tae Ho , Luo ManLi , Huang Pengyu , Liao Pei-Hsin , Wei Shuo , Li Fu-An , Chen Ruey-Hwa , Zhou Xiao Zhen , Shih Hsiu-Ming , Lu Kun Ping
Published: March 2023

Supplementary Text- PDF file 135K, Text for the supplementary information
Supplementary Table 6 from Proteomic Portrait of Human Breast Cancer Progression Identifies Novel Prognostic Markers
Authors: Geiger Tamar , Madden Stephen F. , Gallagher William M. , Cox Juergen , Mann Matthias
Published: March 2023

XLS file - 32K
Supplementary Methods and Figure Legends from Neuropilin-1–Dependent Regulation of EGF-Receptor Signaling
Authors: Rizzolio Sabrina , Rabinowicz Noa , Rainero Elena , Lanzetti Letizia , Serini Guido , Norman Jim , Neufeld Gera , Tamagnone Luca
Published: March 2023

PDF file, 174K
Supplementary Table 2 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells
Authors: Shien Kazuhiko , Toyooka Shinichi , Yamamoto Hiromasa , Soh Junichi , Jida Masaru , Thu Kelsie L. , Hashida Shinsuke , Maki Yuho , Ichihara Eiki , Asano Hiroaki , Tsukuda Kazunori , Takigawa Nagio , Kiura Katsuyuki , Gazdar Adi F. , Lam Wan L. , Miyoshi Shinichiro
Published: March 2023

PDF file - 186K, Results of expression profiling analysis.
Supplementary Figure Legends 1-6, Table Legend 1 from Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
Authors: Wong Christina S.F. , Sceneay Jaclyn , House Colin M. , Halse Heloise M. , Liu Mira C.P. , George Joshy , Hunnam Titaina C.U. Potdevin , Parker Belinda S. , Haviv Izhak , Ronai Ze'ev , Cullinane Carleen , Bowtell David D. , Möller Andreas
Published: March 2023

PDF file - 96K
Supplementary Figure 1 from Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
Authors: Wong Christina S.F. , Sceneay Jaclyn , House Colin M. , Halse Heloise M. , Liu Mira C.P. , George Joshy , Hunnam Titaina C.U. Potdevin , Parker Belinda S. , Haviv Izhak , Ronai Ze'ev , Cullinane Carleen , Bowtell David D. , Möller Andreas
Published: March 2023

PDF file - 293K
Supplementary Table 1 from Human TH17 Immune Cells Specific for the Tumor Antigen MAGE-A3 Convert to IFN-γ–Secreting Cells as They Differentiate into Effector T Cells In Vivo
Authors: Hamaï Ahmed , Pignon Pascale , Raimbaud Isabelle , Duperrier-Amouriaux Karine , Senellart Hélène , Hiret Sandrine , Douillard Jean-Yves , Bennouna Jaafar , Ayyoub Maha , Valmori Danila
Published: March 2023

PDF file - 49K
Supplementary Methods from Human TH17 Immune Cells Specific for the Tumor Antigen MAGE-A3 Convert to IFN-γ–Secreting Cells as They Differentiate into Effector T Cells In Vivo
Authors: Hamaï Ahmed , Pignon Pascale , Raimbaud Isabelle , Duperrier-Amouriaux Karine , Senellart Hélène , Hiret Sandrine , Douillard Jean-Yves , Bennouna Jaafar , Ayyoub Maha , Valmori Danila
Published: March 2023

PDF file - 42K
Supplementary Figure 2 from Metronomic Dosing of BH3 Mimetic Small Molecule Yields Robust Antiangiogenic and Antitumor Effects
Authors: Imai Atsushi , Zeitlin Benjamin D. , Visioli Fernanda , Dong Zhihong , Zhang Zhaocheng , Krishnamurthy Sudha , Light Emily , Worden Frank , Wang Shaomeng , Nör Jacques E.
Published: March 2023

PDF file - 9.2K
Supplementary Figure 1 from Human TH17 Immune Cells Specific for the Tumor Antigen MAGE-A3 Convert to IFN-γ–Secreting Cells as They Differentiate into Effector T Cells In Vivo
Authors: Hamaï Ahmed , Pignon Pascale , Raimbaud Isabelle , Duperrier-Amouriaux Karine , Senellart Hélène , Hiret Sandrine , Douillard Jean-Yves , Bennouna Jaafar , Ayyoub Maha , Valmori Danila
Published: March 2023

PDF file - 212K
Supplementary Figure 1 from Metronomic Dosing of BH3 Mimetic Small Molecule Yields Robust Antiangiogenic and Antitumor Effects
Authors: Imai Atsushi , Zeitlin Benjamin D. , Visioli Fernanda , Dong Zhihong , Zhang Zhaocheng , Krishnamurthy Sudha , Light Emily , Worden Frank , Wang Shaomeng , Nör Jacques E.
Published: March 2023

PDF file - 6.7MB
Supplementary Figures 1-12 from Immunotherapy with PI3K Inhibitor and Toll-Like Receptor Agonist Induces IFN-γ+IL-17+ Polyfunctional T Cells That Mediate Rejection of Murine Tumors
Authors: Marshall Neil A. , Galvin Karen C. , Corcoran Anna-Maria B. , Boon Louis , Higgs Rowan , Mills Kingston H.G.
Published: March 2023

PDF file - 666K
Supplementary Legends for Table 1 and Figures 1-5 from HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
Authors: Nowsheen Somaira , Cooper Tiffiny , Bonner James A. , LoBuglio Albert F. , Yang Eddy S.
Published: March 2023

PDF file - 95K
Supplementary Figure 4 from HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
Authors: Nowsheen Somaira , Cooper Tiffiny , Bonner James A. , LoBuglio Albert F. , Yang Eddy S.
Published: March 2023

PDF file - 45K, ABT-888 reduces levels of the NFkappaB regulated protein cMyc
Supplementary Figure 2 from HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
Authors: Nowsheen Somaira , Cooper Tiffiny , Bonner James A. , LoBuglio Albert F. , Yang Eddy S.
Published: March 2023

PDF file - 25K, Homologous recombination repair capacity in MCF7 cells
Supplementary Table 1 from TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Authors: Yang Yonghong , Wang Xingmin , Moore Danny R. , Lightfoot Stanley A. , Huycke Mark M.
Published: March 2023

PDF file - 59K, primers used for RT-PCR
Supplementary Table 1 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 31K
Supplementary Figure 5 from TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Authors: Yang Yonghong , Wang Xingmin , Moore Danny R. , Lightfoot Stanley A. , Huycke Mark M.
Published: March 2023

PDF file - 138K, showing scant TNF-alpha production from untreated YAMC cells
Supplementary Figure 3 from TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Authors: Yang Yonghong , Wang Xingmin , Moore Danny R. , Lightfoot Stanley A. , Huycke Mark M.
Published: March 2023

PDF file - 1.3MB, showing RT-PCR for Ntn1, Tnfrsf1a, and Tnfrsf1b
Supplementary Figure 1 from TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Authors: Yang Yonghong , Wang Xingmin , Moore Danny R. , Lightfoot Stanley A. , Huycke Mark M.
Published: March 2023

PDF file - 1.3MB, showing E. faecalis-infected macrophages produce TNF-alpha
Supplementary Figure 1 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 1.6K
Supplementary Figure 4 from Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells
Authors: Cui Jiajun , Germer Katherine , Wu Tianying , Wang Jiang , Luo Jia , Wang Shao-chun , Wang Qianben , Zhang Xiaoting
Published: March 2023

PDF file - 89K, ChIP assays of the role MED1 on the recruitment of ERalpha, CBP and HDAC1 using TFF1 promoter
Supplementary Figure 3 from Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells
Authors: Cui Jiajun , Germer Katherine , Wu Tianying , Wang Jiang , Luo Jia , Wang Shao-chun , Wang Qianben , Zhang Xiaoting
Published: March 2023

PDF file - 145K, ChIP-re-ChIP studies of ERalpha with MED1, NCoR or SMRT on TFF1 promoter in response to tamoxifen treatments
Supplementary Figure 2 from Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells
Authors: Cui Jiajun , Germer Katherine , Wu Tianying , Wang Jiang , Luo Jia , Wang Shao-chun , Wang Qianben , Zhang Xiaoting
Published: March 2023

PDF file - 65K, Role of MED1 knockdown on ERalpha mRNA expression in MCF-7/HER2 cells by real-time PCR
Supplementary Figure 1 from Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells
Authors: Cui Jiajun , Germer Katherine , Wu Tianying , Wang Jiang , Luo Jia , Wang Shao-chun , Wang Qianben , Zhang Xiaoting
Published: March 2023

PDF file - 159K, Growth assays of MED1 knockdown effects on the tamoxifen sensitivity of control MCF-7 and HER2 overexpessing cells.
Supplementary Video 8 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: March 2023

MOV file - 1.6MB, Effects of Pi3k Inhibitor LY294002 on Ras-driven luminal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive luminalRas/GFP (MMTV-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and LY294002 in 3D
Supplementary Movie Legend from β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma
Authors: Carbonell W. Shawn , DeLay Michael , Jahangiri Arman , Park Catherine C. , Aghi Manish K.
Published: March 2023

PDF file - 70K
Supplementary Movie 2 from β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma
Authors: Carbonell W. Shawn , DeLay Michael , Jahangiri Arman , Park Catherine C. , Aghi Manish K.
Published: March 2023

MOV file - 1367K, Supplementary Movie 2. Beta1 Integrin Knockdown Impairs BRG Migration. Related to Figure 2. Timelapse phase-contrast imaging of BRG3 bevacizumab-resistant cells on fibronectin demonstrates mesenchymal migration of control (shCTRL, left) cells into the wound in a scratch wound assay. In contrast, migration of beta1 knockdown cells (shB1-c6, right) is significantly attenuated . As in Supplementary Movie 1, knockdown cells demonstrate impaired ability to spread upon the fibronectin substrate (rounded, phasebright cells). Movie images captured with a 40x objective representing approximately 16 hours of imaging, 35 minutes between each frame.
Supplementary Video 2 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: March 2023

MOV file - 2.1MB, Live cell imaging of an MMTV-rtTA/TGFP organoids. Representative video depicting an organoid prepared from a Dox-naive luminalGFP (MMTV-rtTA/TGFP) mouse cultured in 3D with Dox
Supplementary Table 3 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF file - 58K, Specificity of Pak inhibitors
Supplementary Methods from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF file - 153K