bluuebunny/crossref_metadata_2025 huggingface dataset:
FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA KEUANGAN PERUSAHAAN YANG TERDAFTAR DI BEI PERIODE
Authors: Rini Tri Hastuti Vina Meiliana,
Published: April 2022

The purpose of this research is to analyse the effect of leverage, activity, and firm growth on financial performance of manufacturing company listed on the Indonesia Stock Exchange (IDX) during period 2016-2018. Sampling in this study used a purposive sampling method. The sample used is 112 samples. The result of this research showed that leverage has significant negative impact on financial performance, activity has significant positive impact on financial performance, and firm growth has insignificant positive impact on financial performance.
PENGARUH FINANCIAL LEVERAGE, FIRM SIZE DAN FREE CASH FLOW TERHADAP FINANCIAL PERFORMANCE
Authors: Ardiansyah Veronika Crecentia Quan,
Published: April 2022

The purpose of this research is to obtain empirical evidence about the effects of financial  leverage,  firm  size,  andfree cash  flowonfinancial  performancein  manufacturing industries listed in Indonesian Stock Exchange during the period of 2016-2018. This research used 69samples of manufacturing companies that have been previously selected using purposive sampling method. Secondary data was used in the form of financial information from the financial statements and annual reports. This research data was processed using EViews 10. The result of this research shows that financial leverage has a significant effect on financial performance, while firm size and free cash flow does not have a significant effect on financial performance. Suggestions for the next study is to add another independent variables to be able to strengthen the ability of independent variables in explaining the dependent variable, such as intellectual capital, company age, and liquidity.
PERSEPSI WAJIB PAJAK ORANG PRIBADI DI JAKARTA TERHADAP PENGGELAPAN PAJAK (TAX EVASION)
Authors: Ngadiman Celine Meidita,
Published: April 2022

The success of self-assessment system is voluntary compliance with the tax laws. The purposes of this study are to examine the relationship between  tax knowledge,  tax fairness, law enforcement level towards tax evasion behavior of registered individual taxpayers in KPP DKI Jakarta.  Type of this research is quantitative research by using primary data. Sampling was done using purposive sampling with 90 individual taxpayers respondent in Jakarta. The result of double regression test shows that the impact of tax knowledge, tax fairness, and law enforcement level simultaneously affect to the tax evasion behavior. Three independent variables affect the dependent variable is 34,1%, which means 34,1% variation from tax evasion explained by tax knowledge, tax fairness, and law enforcement level.
PENGARUH PROFITABILITAS, LIKUIDITAS, LEVERAGE, UKURAN PERUSAHAAN DAN KEBIJAKAN DIVIDEN TERHADAP NILAI PERUSAHAAN
Authors: Viriany Tommy Dwiputra,
Published: April 2022

The purpose of this research is to examine empirical evidence the influence of profitability, liquidity, leverage, firm size, and dividend policy toward firm value on manufacturing companies listed in the Indonesian Stock Exchange in the period of 2016-2018. The sample in this research was determined by purposive sampling method. The research conducted by taking 40 manufacturing companies. The result of this research shows that profitability has a negative significant effect on firm value, leverage has a positive significant on firm value. Liquidity, firm size, and dividend policy have no significant effect on firm value.
FAKTOR-FAKTOR YANG MEMPENGARUHI CASH HOLDING PADA PERUSAHAAN MANUFAKTUR DI INDONESIA
Authors: Merry Susanti Gionia,
Published: April 2022

The purpose of this study was to examine the effect of firm size, net working capital, cash flow, cash conversion cycle, leverage and growth opportunities on cash holding. The population of this study are all manufacturing companies listed in Indonesia Stock Exchange (IDX) period 2016-2018. The data used in this study is collected through purposive sampling technique where 76 companies met the criteria in this study and were analyze using Eviews 10 with fixed effect model to test the hypothesis. The research shows that net working capital and leverage have a positive effect on cash holding. Cash conversion cycle and growth opportunities have a negative effect on cash holding. Finally, firm size and cash flow do not have effect on cash holding.
PENGARUH PROFITABILITAS, LIKUIDITAS, DAN SOLVABILITAS TERHADAP NILAI PERUSAHAAN
Authors: Jonnardi Elizabeth Yustina Andy,
Published: April 2022

This study aimed to examine the influence of firm profitability, firm liquidity, and firm solvability toward firm value. The population in this research is a number of 54 companies listed on the Indonesia Stock Exchange 2014-2018. The number of samples is 48 companies over the past five years, there are 240 samples. Sample was selected by using simple random sampling method. Data processing techniques in this research using program Eviews version 10.0. The results of this research indicate that all independent variables simultaneously have a significant effect on firm value. The partially test indicate that profitability has positive and significant effect on firm value, liquidity has negative and significant effect on firm value, while solvability has not significant effect on firm value.
FAKTOR-FAKTOR YANG MEMPENGARUHI CASH HOLDING PADA PERUSAHAAN MANUFAKTUR TAHUN 2016 – 2018
Authors: M. F. Djeni Indrajati W Corry Christina, Elizabeth Sugiarto D,
Published: April 2022

The purpose of this study is to obtain empirical evidence about factors that affect on Cash Holding at Manufacturing Companies listed in Indonesia Stock Exchange during 2016-2018. The number of samples used amounted to 64 companies by using purposive sampling method. This study used time series data analysis to test relationship between the factors that is used with Cash Holdings. The result of this study is Leverage and Capital Expenditure do not have significant to influence Cash Holding while Net Working Capital and Profitability have significant positive to Cash Holding.
PENGARUH INTELLECTUAL CAPITAL , FREE CASH FLOW, DAN STRUKTUR MODAL TERHADAP KINERJA KEUANGAN
Authors: Augustpaosa Nariman Catherine,
Published: April 2022

This research aims to determine the effect intellectual capital, free cash flow and capital structure toward the financial perfomance. This research uses 75 samples manufacturing companies listed on the Indonesia Stock Exchange in the year of 2016-2018 using Eviews 10. The results of t test indicate that intellectual capital have a negative unsignificant effect on financial performance. Free cash flow have a negative significant effect on financial performance and capital structure have positive unsignificant effect on financial performance. The results of this research indicate that all independent variables simultaneously have a significant effect on dividend policy (F test).
PENGARUH CAPITAL STRUCTURE, GROWTH OPPORTUNITIES, DAN ACCOUNTING CONSERVATISM TERHADAP EARNINGS RESPONSE COEFFICIENT
Authors: Widyasari Elvara Stephanie,
Published: April 2022

The aim of this research is to empirically examine the influence of the capital structure, growth opportunities, and accounting conservatism of the earnings response coefficient on manufacturing companies listed in the Indonesian Stock Exchange in the period of 2016-2018. The sample selection is done by purposive sampling method, and obtained a sample of 54 companies in this research. The result of this research shows that capital structure and growth opportunities have no significant effect on earnings response coefficient, but accounting conservatism negatively affects earnings response coefficient.
FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA PERUSAHAAN YANG TERDAFTAR DI BEI PERIODE 2016-2018
Authors: Viriany Thomas Adrian,
Published: April 2022

The purpose of this research is to examine the effect of liquidity, financial leverage, and firm size on firm performance of manufacturing company listed on Indonesia Stock Exchange (IDX) during period 2016-2018. The sample used is 72 companies. The results showed that liquidity variable has significant negative impact on firm performance, financial leverage variable has insignificant positive impact on firm performance, and firm size variable has insignificant negative impact on firm performance.
FAKTOR-FAKTOR YANG MEMPENGARUHI CASH HOLDING
Authors: Rini Tri Hastuti Brigita Natalia,
Published: April 2022

This research aims to prove empirically the influence of firm size, cash holding, networking capital, and leverage towards cash holding in the manufacturing company listed in Indonesian Exchange Stock (IDX) in 2016-2018. This research uses 67 samples of manufacturing companies selected using purposive sampling method with a three-year period. Data used in this research is a secondary data. The data processing in this study uses the program EViews ver. 10.0. The test results of F-Anova shows that the firm size, cash flow, net working capital, and leverage have significant effect towards cash holding together. T test result shows that firm size, cash flow, and leverage do not have a significant effect on cash holding while the networking capital have negative significant effect towards cash holding.
FAKTOR YANG MEMPENGARUHI CORPORATE INVESTMENT PADA PERUSAHAAN MANUFAKTUR DI BEI
Authors: Yanti Sheren Lorenzia Kusuma,
Published: April 2022

Purpose of this thesis is to investigate factors influencing corporate investment of manufacturing companies listed in Indonesia Stick Exchange (IDX). This research done by panel data that have been selected using purposive sampling method for 30 listed manufacturing companies for the periods of 2015-2018. This research used Eviews version 10 software to process the data. The result of research shows that cash flow is not influencing the corporate investment. These results support the pecking order theory that sugest that companies will use internal funding sources first rather than using external funding. Leverage, growth opportunities, cash and liquids, liquidity, and sales are found to have an effect on corporate investment.
PENGARUH KEPEMILIKAN MANAJERIAL, KEPEMILIKAN INSTITUSIONAL, DAN UKURAN PERUSAHAAN TERHADAP KINERJA PERUSAHAAN MNUFAKTUR
Authors: Henryanto Wijaya Joshua Gunawan,
Published: April 2022

This study was conducted to determine the effect of managerial ownership, institutional ownership, and company size on the performance of manufacturing companies listed on the Indonesia Stock Exchange in 2015-2018. The sample selection technique used in this study uses a purposive sampling technique where the selected sample is based on various considerations and certain criteria that are tailored to the purpose of the study. Based on the specified criteria, the researchers obtained 38 manufacturing companies. The results of this study indicate managerial ownership have a positive and significant effect on company performance, institutional ownership have a positive and significant effect on company performance, and company size has a positive and not significant effect on company performance.
PENGARUH CASH HOLDING DAN TANGIBILITY TERHADAP FIRM PERFORMANCE DENGAN HUTANG SEBAGAI MODERASI
Authors: F.X.Kurniawan Tjakrawala Lieta Tandra,
Published: April 2022

This study was conducted to test and determine whether the Cash Holding and Tangibility variables, if added by the moderating variable Debt, can have an effect that strengthens or weakens Firm Performance. The population in this study are Real Estate Companies listed on the Indonesia Stock Exchange for the period of 2016-2018. This study used a sample of 47 company samples and used the Eviews 10.0 program as a data processing program. The results showed that the debt variable does not affect Cash Holding on Firm Performance, while the debt variable weakens the effect of Tangibility on Firm Performance.
Clinical experience with sesame oral immunotherapy and a quality-of-life assessment
Authors: You Lucia C. , Soffer Gary , Factor Jeffrey
Published: April 2022

Background: Allergic reactions to sesame have increased in prevalence in the United States. Sesame oral immunotherapy (OIT) is an emerging management strategy. Few reports assessed the benefits and risks of sesame OIT in children with sesame allergy. Objective:
To study the adverse events and quality of life (QoL) on sesame OIT in a U.S. population. Methods: Twenty-three patient charts were retrospectively reviewed from 2017 to 2020. The patients received a validated Food Allergy Quality of Life Questionnaire and a survey
on adverse reactions during maintenance therapy. Patients who were 8.5 ± 4.7 years of age (30% girls and 70% boys) with a documented history of sesame allergy and who had undergone sesame OIT were reviewed. Results: The buildup phase was 293.7 ± 87.1 days.
Twenty-one of the 23 patients (91.3%) reached maintenance therapy. Twenty-one patients (91.3%) had at least one gastrointestinal reaction; 18 (78.3%) had at least one cutaneous reaction; 6 (26%) had at least one respiratory reaction. Age raised the odds of gastrointestinal reactions more than
fivefold (odds ratio [OR] 5.653 (95% confidence interval [CI], 2.409 ‐ 13.269); p = 0.0009). Asthma boosted the odds of respiratory reactions of more than ninefold (OR 9.206 [95% CI, 1.535 ‐ 55.211]; p = 0.0187). Female gender increased the odds of having a respiratory reaction
by more than sevenfold (OR 7.545 [95% CI, 1.207 ‐ 47.153]; p = 0.0330). Asthma amplified the odds of cutaneous reactions (OR 11.725 [95% CI, 2.390 ‐ 57.517]; p = 0.0053). Three patients ultimately discontinued therapy. Food-related anxiety (‐0.773) and social/dietary limitation
(‐0.687) improved significantly in QoL. Conclusion: Sesame OIT may be safe and easily adaptable to private practice and significantly improves QoL. Further prospective studies would be helpful to fully assess these relationships.
Karakteristik Mutu Sensori Bakso Nabati Rumput Laut
Authors: Yudiastuti Silvia Oktavia Nur , Wahyono Agung , Budiati Titik , Arsiwi Maudiadwi
Published: April 2022

Meatballs are a food favored by the community, with the number of buyers classified as frequent at +30% even though the calories are high, reaching 68 calories per piece with a fat content of 60%. The purpose of this study was to produce vegetable meatballs with lower fat but high fiber content. The vegetable meatballs in this study were produced using Eucheuma cottonii seaweed gel without meat and wheat flour as its raw materials. The vegetable meatballs can be intended for consumers with certain conditions. The research method used was experimental using a randomized block design (RAK). The treatment in this study was the concentration of E.cottonii seaweed gel in the product formulation which was 0.5%, 1%, 1.5%, 2%, and 2.5%. Each treatment was repeated three times. The observed response was consumers' acceptance using hedonic and hedonic quality tests and the fat content of meatballs. The results showed that vegetable meatballs with 1.5% gel content were the most preferred by panelists which contain 3.5% crude fiber and 14% fat.
Teknik Dehidrasi Osmosis Pada Pembuatan Manisan Kulit Jeruk
Authors: Givari Teuku Augibran , Hawa La Choviya , Putranto Angky Wahyu
Published: April 2022

High consumption of oranges (Citrus sinensis) leads to the increase of orange peel waste, that’s why those orange peel waste needs to be utilized as a value-added product, such as fruit candy. Fruit candy can be produced by a process called osmotic dehydration, which is the process of immersing food material in a hypertonic solution. This research was done with Randomized Block Design to understand the effect of immersion time (2, 4, and 6 hours) and blanching time as the pretreatment (2,5, 5, and 7,5 minutes). This research was done in triplicate. The parameters that were observed are solid gain (SG), water loss (WL), weight reduction (WR), water content, and colors (L*, a*, and b*). The results indicated that the increase in immersion and blanching time causes the value of solid gain (SG) and water loss (WL) to increase, weight reduction to decrease then increase, and water content to decrease. Analysis of Variance test suggests that immersion time has a significant effect on SG, WL, WR, water content, L*, and a*. On the other hand, blanching time only significantly affects SG, WL, WR, and water content. According to Multiple Attribute Utility Theory, the best treatment in this research, regarding the results of SG, WL, WR, and water content, is the treatment with 6 hours immersion time and 7,5 minutes blanching time.
La reseña académica: caracterización teórica y tipológica
Authors: Mostacero Rudy
Published: April 2022

La reseña es un macro-género de carácter evaluativo que se da a conocer en revistas especializadas, pero a diferencia de otros géneros como el artículo de investigación, ha recibido escasa atención. El propósito de este artículo es abordar las concepciones teóricas sobre la reseña académica, su tipología y las relaciones textuales que están implícitas tanto en su estructura como en su construcción discursiva. Por esa razón, el énfasis estará puesto en la especificación de sus fundamentos epistemológicos. No obstante, por ser un tema muy amplio, se hará una síntesis de su variación tipológica. Con este artículo de reflexión se desea contribuir a un mejor conocimiento de un género que tiene un impacto decisivo en la transformación y socialización del conocimiento científico.
Preparation and property analysis of solid carbonate-oxide composite materials for an electrolyte used in low-temperature solid oxide fuel cell
Authors: Liang Yong-Xin , Ma Ze-Rong , Yu Si-Ting , He Xin-Yue , Ke Xu-Yang , Yan Ri-Feng , Liang Xiao-Xian , Wu Xin , Huang Rui-Sen , Wen Liang-Cheng , Cao Gengyu
Published: April 2022

The oxide-carbonate composite electrolyte material with high ionic conductivity at low temperature has been thought that it can be used to develop LT-SOFC. However, the carbonate composite electrolyte is not easy to make it dense, especially mixing and packing oxide and carbonate to fabricate the composite electrolyte simply. In this article, rare-earth-doped CeO2 (RDC) (R = La, Sm, Gd, and Gd + Y) series samples were prepared by wet ball-milling, then sintered into fully dense and porous oxide bulk at 1500–1600 °C and 1000 °C. Melted carbonate LNCO, composed of Li2CO3 and Na2CO3 at a molar ratio of 1:1, was combined with porous oxide bulk materials using a bath method at 500 °C for 10 h to prepare a dense carbonate-oxide composite electrolyte. The dense oxide-carbonate composite electrolyte always obtains by this fabrication process. Boiling water was used to remove carbonate from these composites. Lattice parameters were obtained through Rietveld refinement, and a calculation procedure for quantifying the composite density was proposed. The quantified composite density results were verified through scanning electron microscopy microstructure observations. The Ce valence in the RDC oxides and RDC-carbonate composite was analyzed by X-ray absorption near edge structure spectroscopy to observe the effects of heat treatment temperature and carbonate on the Ce4+/Ce3+ mixed-valence state in doped CeO2.
Description of the unknown male of Conocephalus yunnanensis Shi et Feng, 2009 (Othoptera: Tettigoniidae)
Authors:   College of Life Sciences, Hebei University, Baoding 071002, P. R. China, Duan Y.H. , Shi F.M. ,   College of Life Sciences, Hebei University, Baoding 071002, P. R. China
Published: April 2022

The previously unknown male of Conocephalus (Anisoptera) yunnanensis Shi et Feng, 2009 is described for the first time. The female of this species is redescribed. The photographs of habitus and characteristic taxonomic features of both sexes are also provided.
A gestante tardia e os riscos para Síndrome de Down: uma revisão de literatura
Authors: Ferreira Débora Furtado , Oliveira Carla Resende Vaz , Gonçalves Michelly Hellem Alves de Freitas , Reis Bruno Cesario Costa
Published: April 2022

Objetivo: Identificar os principais riscos para a ocorrência da Síndrome de Down nas gestantes mais tardias. Métodos: A abordagem metodológica deste trabalho se propõe a um compilado de pesquisa bibliográfica de abordagem qualitativa e caráter descritivo por meio de uma revisão integrativa da literatura. As bases de dados utilizadas foram o National Library of Medicine (PubMed), Biblioteca Virtual em Saúde (BVS) e Directory of Open Access Journals (DOAJ). Os descritores utilizados foram “Prenatal”, “Down syndrome” e “Maternal Age”. Os critérios de inclusão foram artigos de journal article, clinical trial, ensaios clínicos, randomizados ou não randomizados, estudos de caso-controle, estudo de coorte, livre acesso, publicados em inglês, português, espanhol, no intervalo de 2017 a 2022 e faixa etária acima de 35 anos. Resultados: O principal fator de risco para a ocorrência da Síndrome de Down foi a idade materna avançada acima de 35 anos (80%). O segundo fator de risco identificado foram as alterações citogenéticas da mãe (26,6%). Considerações finais: O estudo demonstrou consonância com a literatura existente, onde o principal fator de risco para Síndrome de Down na gestante tardia é a sua idade avançada entre 35-45 anos, aumentando a incidência conforme a idade aumenta.
Padrão dos métodos diagnósticos oftalmológicos usados para o diagnóstico precoce de retinopatia diabética: uma revisão de literatura
Authors: Corrêa Marianna da Cunha , Oliveira Aline de Jesus , Tavares Bruno da Silva , Oliveira Carla Resende Vaz , Santos Maria Thereza Castilho dos , Sarmento Phelipe Von Der Heide , Martins Thales Montela , Reis Bruno Cezario Costa
Published: April 2022

Objetivo: Analisar o padrão dos métodos diagnósticos oftalmológicos usados para o diagnóstico precoce de Retinopatia diabética. Métodos: A abordagem metodológica deste trabalho se propõe a compilar estudos bibliográficos com métodos qualitativos e características descritivas por meio de uma ampla revisão bibliográfica das bases de dados National Library of Medicine, Virtual Health Library e Cochrane Library. Os descritores utilizados “diabetic retinopathy”, “complications of diabetes mellitus”, “ophthalmologic diagnostic” e ”aged”. Os critérios de inclusão foram artigos de periódicos, ensaios clínicos, ensaios clínicos, randomizados ou não randomizados, estudos caso-controle, estudos de coorte, acesso livre, publicados em inglês, português, espanhol, variando de 2017 a 2022, faixa etária maior ou igual a 65 anos. Resultados: A detecção precoce é importantíssima para a eficácia dos tratamentos, pois quanto maior sua gravidade pior é o resultado da terapia. Existem inúmeros exames oftalmológico em uso atualmente sendo eles mapeamento de retina, angiografia da retina, Tomografia de Coerência Óptica (OCT) e ultrassom do olho. Considerações Finais: Dessa forma, a OCT é principal método diagnóstico, sendo ele precoce e fidedigno, promovendo uma observação minuciosa a respeito da rede vascular.
A utilização da escala Perme como um instrumento de avaliação na Unidades de Terapia Intensiva
Authors: Costa Rayana Fialho da , Silva Italo Caldas , Mota Antonia Vitória Silva , Albuquerque Thayse Saraiva de , Silva Francisco Vandecir da , Miranda Larissa Rocha , Almondes Jardel Gonçalves de Sousa , Campos Nataly Gurgel
Published: April 2022

Objetivo: Investigar a utilização da escala Perme como instrumento de avaliação nas Unidades de Terapia Intensiva (UTI). Métodos: Trata-se de uma revisão integrativa de literatura com busca de artigos nas bases de dados PubMed, PEDro, Medline, EMBASE e SciELO no período de dezembro de 2020 a março de 2021, nos idiomas inglês, português e espanhol. Resultados: Quatro artigos foram selecionados e discutidos, datados de 2019 e 2020, sendo três longitudinais prospectivos e um ensaio clínico controlado não randomizado. As amostras contemplaram de 18 a 33 pacientes, com idade entre 58 a 64 anos. Considerações finais: Nesse atual estudo, mostra que a escala Perme, embora seja um instrumento capaz de mensurar a melhora da mobilidade em pacientes críticos, possibilitar prognósticos, embasar possíveis estratégias terapêuticas de forma individual com o objetivo de resgatar e manter o máximo nível de mobilidade até o momento da alta da UTI, parece ser pouco empregada para o diagnóstico cinético funcional e prescrição terapêutica.
O impacto da hipertensão arterial sistêmica no contágio e prognóstico da Covid-19: uma revisão narrativa
Authors: Gerbassi Ricardo Rocha , Ribeiro Adriely Cristina Coronel , Belo Fernanda Fabrícia Resende , Coelho Jamilly Gusmão
Published: April 2022

Objetivo: Compreender o impacto da Hipertensão Arterial Sistêmica (HAS) no contágio e no prognóstico da COVID-19. Revisão bibliográfica: A HAS é uma condição causada por vários fatores e é caracterizada por altos níveis sustentados de Pressão Arterial (PA). Considerada um dos principais fatores de risco para as doenças cardiovasculares, a hipertensão arterial tem necessitado de um olhar diferenciado durante a pandemia por estar associada a um maior número de complicações e mortes em caso de infecção pelo coronavírus. A hipertensão é responsável de alguma forma por metade das mortes por doenças cardiovasculares em todo o mundo, atinge uma média de 1/4 da população adulta e responde por cerca de mais de 300 mil óbitos anuais, segundo a Sociedade Brasileira de Hipertensão (SBH). A hipertensão é responsável por mais de 70% dos casos de Acidente Vascular Cerebral (AVC) e o maior risco para hipertensos com COVID é que o vírus produz uma reação inflamatória que pode atingir áreas vasculares, como vasos que apresentam mudanças na sua estrutura ou na sua função. Considerações finais: Dessa forma, torna-se necessário estudos relacionando hipertensão arterial sistêmica com o contágio da covid-19 e seu prognóstico, visando maior conhecimento sobre o assunto.
Endovascular treatment of massive hemorrhage from a radiation-induced iliac artery-enteric fistula: A case report and review of the literature
Authors: Isaac Mina F. G. , Mirpuri Tarun Mohan , Kumar Pradesh , Ho Chi Long
Published: April 2022

Arterioenteric fistula is a rare cause of massive gastrointestinal tract hemorrhage. It is defined as an abnormal communication between an artery and a bowel loop. Radiation-induced iliac artery-enteric fistula (IEF) is an extremely rare subtype with only a few cases reported in the literature. Here, we present a case of successful endovascular treatment of massive hemorrhage due to radiation-induced IEF.
Brain abscess caused by Nocardia thailandica infection in systemic lupus erythematosus patient with steroid therapy
Authors: Yagi Ryokichi , Ooi Yukimasa , Nonoguchi Naosuke , Wanibuchi Masahiko
Published: April 2022

Background:

Nocardia is an aerobic Gram-negative bacillus belonging to actinomycetes and has been reported to be an infectious disease in healthy individuals. However, more than 60% have some underlying illnesses and are said to be opportunistic infections.

Case Description:

The case was a 69-year-old man who had been on long-term steroids for systemic lupus erythematosus. He developed with nausea and gait disturbance and was suspected of having a brain abscess by imaging. Abscess drainage detects actinomycetes that appear to belong to the genus Nocardia and brain abscess by Nocardia thailandica using matrix-assisted laser desorption/ionization time-of-flight mass analysis (MALDITOFMS) I was diagnosed. He died during the course of the treatment, and his organs did not detect his N. thailandica at necropsy, so he concluded that bacterial death from long-term administration of antibiotics was the cause of death.

Conclusion:

N. thailandica is a very rare bacterium belonging to Nocardia asteroides and is said to easily form brain lesions. In immunocompromised patients, prophylaxis with antibiotics and detailed examination of lung lesions for surveillance were considered necessary. This paper is the first report of a brain abscess caused by N. thailandica, including a review of the literature.
Der Scherz des Falstaff war nicht sein letztes Wort
Authors: Sühring Peter
Published: April 2022

The entire production of Verdi's sacred music within his forward and backward-looking work history is summarized and commented on. The focus is on his Messa da Requiem (1874) and his Tre pezzi sacri (the late 1890s). Also addressed are his early works, such as Messa di Gloria (1833–35) and a Tantum Ergo (1836), as well as his contributions in the form of interludes in his operas and his first version of Libera me from the Requiem for Rossini (1869), the three Ave Marias from the 1880s (including one in the 4th act of the opera Otello) as well as a Pater Noster and a late sacred song for soprano and piano.
SPA DENGAN PENDEKATAN ARSITEKTUR TROPIS DI KABUPATEN BENGKAYANG
Authors: Ayunita Rida Rizkika
Published: April 2022

Technological advances in internet use have affected new lifestyles for urban communities. In the time of the Covid-19 virus pandemic, the use of internet technology became more intense because of work, education, and other things implementing the Work From Home (WFH) system. This can trigger stress due to work time and not working that has melted as if it does not know the time. Concerns about the health of urban communities due to high levels of stress give rise to the phenomenon of therapeutic tourism as a means for relaxation and recreation in one area. The design of  “SPA Dengan Pendekatan Arsitektur Tropis di Kabupaten Bengkayang” with destination SPA program is seen as an opportunity aimed at preventing, healing, and restoring one's physical and psychic state. Destination SPA has facilities in the form of complete SPA services, body treatments, hot spring baths, health education, healthy cuisine, beauty treatments, fitness, as well as rental and room service. Samudera Indah Beach is one of the beach attractions in Bengkayang Regency, is a tourism development area with beautiful scenery. Tropical Architecture approach in SPAtial and building arrangement is applied in order to solve tropical climate problems at the design site and can realize natural impressions in accordance with the nature of nature. The methods used in this design, namely the idea stage, the data collection stage, the analysis stage, the synthesis stage, the pre-draft stage, and the planning stage.
PERANCANGAN RUMAH SAKIT IBU DAN ANAK DI KABUPATEN SINTANG
Authors: Gunawan Abdi , Purnomo Yudi , Andi Uray Fery
Published: April 2022

Health is the most important factor in people's lives, especially the health of mothers and children. The increasing number of births and deaths and the increasing number of residents in Sintang Regency as the 3rd largest Regency in West Kalimantan Province, thus requires a health facility that accommodates services for mothers and children. One type of service is the Mother and Child Hospital (RSIA). The design of this hospital is planned in Sintang District, Sintang Regency. This location was taken based on the issue of the importance of RSIA development, and 2019 Central Statistics Agency (BPS) data which shows that health facilities such as hospitals are not evenly distributed in Sintang Regency in Sintang District. The design method used includes: ideas, data collection, analysis, and the design phase, as well as the results of the design of the maternal and child hospital. This design consists of a linear building that follows the shape of the land. Zoning space is divided and adapts to narrow land forms. Orientation, placement and circulation are regulated based on existing regulations and analysis, so that there is a need for circulation paths as needed, and on the facade of the building it is planned to use several window openings that are used as natural lighting and ventilation in the room.
KAWASAN WISATA PANTAI SINAM DI KECAMATAN PEMANGKAT
Authors: Muliadi Muliadi , Caesariadi Tri Wibowo , Khaliesh Hamdil
Published: April 2022

Sambas Regency is an area that has a coastal area stretching from the Semelagi area to the Temajuk Coast region which borders Malaysia. Sinam Beach is one of the tourist attractions, precisely in Pemangkat District. The beach is often visited by tourists on weekends for recreation and relaxation. This Sinam Beach Tourism Area is very worrying because natural disasters often occur in the form of tidal floods, strong winds and coastal abrasion, the inability of the community and local government to utilize and manage existing potentials optimally to create tourist attractions. The purpose of this design is to produce a plan and design for the Sinam Beach Tourism Area in Pemangkat District which can meet the needs of tourists and utilize the potential of natural resources.The concept used is green open space by the beach. The method used in the design is to find ideas, collect data and analyze data. The design of the Sinam Beach Tourism Area creates a tourist zone, namely land tourism, water tourism and mangrove tourism.. Supporting facilities in the design are a tourist information center,management office, public toilets, promenade, floating restaurant and UMKM area.
PENATAAN KAWASAN PELABUHAN RASAU JAYA KABUPATEN KUBU RAYA
Authors: Almaida Tia , Muazir Syaiful , Pebriano Valentinus
Published: April 2022

The Rasau Jaya Port area is a port area located in Kubu Raya Regency which serves shipping routes to the hinterland of West Kalimantan. The journey taken is a cross route within Kubu Raya Regency and a cross route between districts, namely North Kayong Regency. However, judging from the area and the port service office, this is still not feasible for an inter-district port area. Therefore, the Rasau Jaya Port area requires an area arrangement according to existing regulatory standards. The design methodology is adopted in stages, namely ideas, data collection, analysis, synthesis and design. With an area design concept that refers to the functions and standards of ferry port requirements. This can make the port a more organized area like a port in general.
GEDUNG OLAHRAGA KABUPATEN KETAPANG
Authors: Rudianto Eko Wibowo , Putro Jawas Dwijo , Khaliesh Hamdil
Published: April 2022

Ketapang is a district-level area that is constantly developing and trying to improve the welfare of the community. One of these efforts is the development process in various sectors. In line with the growth and development of the development process in these various sectors, the development that is felt to need attention at this time in Ketapang Regency is development in the field of sports. The importance of developing the sports sector in society. Ketapang Regency is based on the level of public awareness of the importance of exercise which is increasing day by day, in line with the recommendations of health experts. This final project aims to design sports facilities that are not only functional but also multifunctional. The Ketapang Regency Sports Building design method is carried out in several stages, namely ideas, theory reviews, data collection, analysis, synthesis, pre-design, and design. The design analysis resulted in several functions of the sports building into three functions, namely primary functions (sports and competitions), secondary functions (administration and recreation), and tertiary functions (maintenance/service). The analysis of the area pattern is taken from the elements of the formation of the sports building area in general by adjusting the location of the site. The characteristics of the sports building follow the shape of the sports building by using a wide span structure with a spaceframe roof system.
C–H Functionalization via Iodine-mediated Electrocatalysis and C–N Bond Formation
Authors: Ahmed Nisar , Martins Guilherme. M.
Published: April 2022

The access of heterocyclic compounds via direct amination of C-H bonds are of vital interest because of their role in pharmaceutical and natural products. The combination of molecular iodine and electricity activates benzylic C-H bond and facilitates the amination process via intramolecular C-N bond formation. Iodine works as a mediator for the formation of C-N bond via activation of a distance C-H bond through intermediate N-I bond under electrochemical conditions, so iodine can be called electrocatalyst. Under both batch & flow electrochemistry conditions, similar results were obtained in cyclization product with 77 & 78% yields respectively. However, in case of annulation reaction higher yield was obtained with 99% conversion under flow electrochemical conditions using our design of home-made flow microreactor. In both electrochemical transformations, cyclization as well as annulation reaction, no photocatalyst was used. Notably, flow reactions work under safe & environmentally friendly conditions, and continuous products are obtained.
A Single Site Mutation Induces a Water-Mediated Promiscuity in Lignin Breaking Cytochrome P450GcoA
Authors: Singh Warispreet , Santos Sonia , James Paul , Black Gary , Huang Meilan , Dubey Kshatresh
Published: April 2022

Cytochrome P450 GcoA is an enzyme that catalyses the guaiacol unit of lignin during the lignin breakdown via aryl-O-demethylation reaction. This reaction is intriguing and is of commercial importance for its potential application in the production of biofuel and plastic from biomass feedstock. Recently, the F169A mutation in the P450 GcoA elicits a promiscuous activity for syringol while maintaining the native activity for guaiacol. Using comprehensive MD simulations and hybrid QM/MM calculations we address, herein, the origin of promiscuity in P450 GcoA and its relevance to the specific activity toward lignin-derived substrates. Our study shows a crucial role of an aromatic dyad, F169, and F395 through regulating the water access to the catalytic center. The F169A mutation opens a water aqueduct and hence increases the native activity for the G-lignin. We show that syringol binds very tightly in the WT enzyme which blocks the conformational rearrangement needed for the second step of O-demethylation. The F169A creates an extra room favoring the conformational rearrangement in the demethylated syringol (3MC) and second dose of the dioxygen insertion. Therefore, using MD simulations and complemented by thorough QM/MM calculations, our study shows how does a single site mutation re-architect active site engineering for promiscuous syringol activity.
Solvent-free Synthesis of polymethoxy and dichloro p-nitrophenyl hydrazones
Authors: Babalola Sodeeq , Idris Abdullah , Sani Yeken , Hamza Asmau , Igie Nosakhare , Muhammad Hayatudeen , Erumiseli Gowin , Bakare Lateef
Published: April 2022

A solvent-free method for the synthesis of novel p-nitrophenyl hydrazones was successfully developed. The condensation of the p-nitrophenyl hydrazine with aromatic aldehydes through this mechanochemical technique furnished three products (3a-c) with moderate to high yield. The developed method is eco-friendly, efficient, simple, and convenient and indicated high reproducibility, short reaction time, catalyst-free, simple workup, and afforded pure and unsolvated products.
Estimation of potential bacteriological hazards and their genetic virulence
determinants in beef meals provided to intensive care patients
Authors: Abo hashem M.E. , Enany M.E. , Huda E.I. , Elsharawy N.T.
Published: April 2022

Meat is a good source of protein which makes it a good substrate for microbial growth. In
this study, the prevalence, antibiogram and virulence genes of some foodborne pathogens
from hospital beef meals provided to intensive care patients were evaluated. Therefore, a
total of 60 beef meat samples (30 raws and 30 cooked samples) were randomly collected
from different hospital kitchens in Ismailia province, Egypt. Samples were subjected to
bacteriological evaluation for Staphylococcus aureus, Escherichia coli and Salmonella.
The obtained results revealed that S. aureus, E. coli and Salmonella were isolated by a
prevalence of 38.3% (23/60), 16.6% (10/60), and 8.3% (5/60), respectively. S. aureus was
highly resistant to penicillin and streptomycin. Escherichia coli was highly resistant to
amoxicillin, streptomycin, ciprofloxacin, gentamicin and ampicillin. Salmonella was
highly resistant to amoxicillin, penicillin and cefpodoxime, ampicillin, gentamicin,
ciprofloxacin and streptomycin. Staphylococcus aureus harboured sea, seb, sec and sed
enterotoxin genes with a prevalence of 13.04%, 4.34%, 13.04 % and 4.34%, respectively.
Escherichia coli isolates harboured stx1 and stx2 with a prevalence of 83.33% and 66.66%,
respectively. Escherichia coli was serotyped as O128, O142, O26 and O157. Salmonella
harboured invA and hilA genes by 100% and 80%, respectively. In conclusion, the
application of good manufacturing practices with well-trained food handlers is necessary
to control and prevent contamination of hospitable meals by foodborne bacteria in order to
protect and save intensive care patients.
Penentuan Cost of Good Sold dan Penerapan Cost Plus Pricing Method dalam Menentukan Harga Jual: Study Penggilingan Padi UD Budi Luhur
Authors: Kartika Erawati , Bakhtiar M. Rifky
Published: April 2022

The cost plus pricing approach in determining the cost of production is very important because this method is more detailed in including the cost components needed in a production process. This situation can affect the determination of the selling price and the resulting profits. The full costing model as the determination of the cost of goods manufactured (HPP) is expected to be a tool for UD Budi Luhur. This study aims to analyze how to determine the selling price at UD Budi Luhur with the selling price according to the cost plus pricing method. The method used is quantitative descriptive method. The results show that the management has not applied cost plus pricing analysis in calculating the selling price. The selling price generated by this method is lower than the method the company has used previously. UD Budi Luhur's management should begin to apply the cost plus pricing method by using a variable cost approach in calculating the selling price so that the selling price achieved by the company can compete with similar products on the market.
Analisa Performa Perusahaan Properti dengan Menggunakan Multi Rasio
Authors: Cakranegara Pandu Adi
Published: April 2022

The development of the population and the increasing middle class have made the demand for property increase in Indonesia. This trend is an opportunity for property companies in Indonesia to sell more properties. Property management can meet this demand, among others, by developing new areas or selling in developed areas at a premium. Each choice will have consequences and will create a trade-off. Therefore this study examines the factors that drive the profitability of the company. The hope is that by focusing on the factors that drive profitability, the company will get the optimum return. The research method used in this research is a quantitative method using multiple linear regression. The research data is secondary data taken from the company's financial statements for 2015 to 2019. This study's findings are that internal factors and external factors both influence the profitability of property companies. This study found four internal factors and one internal factor that affect profitability. Internal factors consist of Debt to Equity Ratio, Net Profit Margin, Total Assets Turnover and Operating Cash Flow. Meanwhile, the external factor that influences it is the interest rate. Managers can focus on these factors to achieve the optimum level of profitability.
Pengaruh Corporate Social Responsibility (CSR) Terhadap Agresivitas Pajak: Studi Empiris pada Perusahaan Pertambangan yang Terdaftar di BEI Tahun 2017
Authors: Nurcahyono Nurcahyono , Kristiana Ida
Published: April 2022

This study aims to examine the effect of Corporate Social Responsibility (CSR) on tax aggressiveness. This research was conducted at mining companies listed on the Indonesia Stock Exchange in 2017 and the sample in this study amounted to 41 companies. Measurement of the CSR variable using dammy and based on the GRI 4.0 index, tax aggressiveness is measured by the Effective Tax Rate. The research method used in this study is multiple linear regression. The results of this study show that corporate social responsibility has a negative effect on tax aggressiveness.
Analisis Pengaruh Kecerdasan Emosional, Kecerdasan Spiritual, dan Love of Money Terhadap Persepsi Etis Mahasiswa Akuntansi Mengenai Etika profesi Akuntan (Studi Kasus Pada Universitas Swasta Jurusan Akuntansi Kota Semarang)
Authors: Mangiskar Laila
Published: April 2022

Abstract____________________________________________________________This research was conducted to determine: (1) the effect of emotional intelligence on the ethical perceptions of accounting students regarding the professional ethics of accountants; (2) The Effect of Spiritual Intelligence on the Ethical Perceptions of Accounting Students Regarding Accountants' Professional Ethics; (3) The Effect of Love of Money on the Ethical Perceptions of Accounting Students Regarding Accountants' Professional Ethics; (4) The simultaneous influence of Emotional Intelligence, Spiritual Intelligence and Love of Miney on Accounting Students 'Ethical Perceptions of Accountants' Professional Ethics. The population in this study were accounting students at the University of Semarang, Sultan Agung Islamic University, Stikubank University, Soegijapranata Catholic University and Dian Nuswantoro University. The sample in this study were 95 respondents. The prerequisite test includes normality test, multicollinearity test, heteroscedasticity test and autocorrelation test. The data analysis technique used to test the hypothesis is multiple linear regression analysis. The results showed that partially Emotional Intelligence had a positive and significant effect on the Ethical Perceptions of Accounting Students Regarding the Professional Ethics of Accountants as evidenced by the regression coefficient value showing the direction of the positive relationship of 0.085 and the sig value of 0.000 <0.050; Spiritual Intelligence has a positive and significant effect on the Ethical Perceptions of Accounting Students Regarding Accountants' Professional Ethics as evidenced by the regression coefficient which shows the direction of the positive relationship of 0.100 and the sig value of 0.000 <0.050; Love of Money has a negative and significant effect on the Ethical Perceptions of Accounting Students Regarding Accountants' Professional Ethics as evidenced by the regression coefficient value which shows the direction of the negative relationship of -0.030 and the sig value of 0.004 <0.050; Emotional Intelligence, Spiritual Intelligence and Love of Money simultaneously influence the Ethical Perceptions of Accounting Students Regarding Accountant Professional Ethics as evidenced by the value of Fcount is greater than Ftable, namely 14.243> 2.70 and a significance value of 0.000 <0.050.