bluuebunny/crossref_metadata_2025 huggingface dataset:
Reduction of Ratio Spectra in UV Spectrophotometry Method for Ecstasy Tablet
Authors: Muchlisyam Muchlisyam , Rimayani Nasution Lisda , Syahputra Hafid
Published: September 2024

The research aims to estimate the simultaneous level of the components of the ecstasy tablet by using the spectral ratio reduction method in combination with methanol and phosphate buffer pH 5 as a solvent. The drugs were dissolved in a methanol and phosphate buffer pH 5 and injected into the GC-MS. The reduction of the ratio spectrum method was validated by the test parameter accuracy, precision, linearity, LOD, and LOQ, and the levels of components in the drug mixtures be determined. It was discovered that GC-MS detected the presence of methamphetamine with retention times of 3.812 and 3.963; ephedrine HCl at 5.301 and 5.779; Paracetamol at 7.552 and 7.614; and Caffeine at 8.685. Based on the spectral ratio reduction method, methamphetamine, ephedrine HCl, Caffeine, and Paracetamol levels are determined at 257.8nm; 257.2nm; 273nm; and 245.6nm, resulting in test results of (39.33; 43.57; 8.85; and 7.18) percent for methamphetamine, ephedrine HCl, Caffeine, and Paracetamol, respectively. Accordingly, GC-MS identified drugs containing methamphetamine, ephedrine HCl, Caffeine, and Paracetamol, that can be determined simultaneously by the reduction method of ratio spectra using a combination of methanol and phosphate buffer pH 5 as a solvent, and meet the validation criteria.
Anaesthetic management for Tympanomastoid Exploration in a Child having a Device Implanted for Patent Ductus Arteriosus correction
Authors: Sen Jayashree , Sen Bitan
Published: September 2024

Children undergoing non-cardiac surgery under anaesthesia even with corrected congenital heart defects have high chances of morbidity and mortality in the peri-operative period. Factors responsible are complicated disease pattern, least or non- compensated physiological status, associated co-morbidities. Opioid and local analgesia, or general anaesthesia with propofol induction and maintenance with sevoflurane or isoflurane are acceptable techniques for anaesthesia. In the current presention, we used an α2- adrenoceptor agonist as an adjunct along with general anaesthesia for a stable haemodynamic status.
In Silico Investigation of Chemical Components of Fragaria ananassa Species as Aphrodisiac Agents for Erectile Dysfunction
Authors: S Sadishkumar , Kumar S Vimal , SN Mohith , R Prathiba , S Abilash , AR Mahesh
Published: September 2024

Sterols, Polyphenols, and flavonoids have a major role in erectile dysfunction. The molecular docking of phytochemical constituents of Fragaria ananassa fruit with human phosphodiesterase 5 (1UDT), human arginase II (4I06), human aromatase (5JKV), D2 dopamine receptor (6CM4) compared with sildenafil citrate. Using BIOVIA Discovery studio, ligand clusters were prepared, and PyRX software was used for molecular docking (Auto dock-Vina). Using PyMOL, the Protein-Ligand Complex was generated, and the 2D- interactions were obtained from BIOVIA Discovery studio. Most of the Phyto-constituents showed better binding affinity than sildenafil citrate. All 58 components have better GI absorption which ranges from 0% to 100%. The physicochemical, pharmacokinetics (ADME), and toxicity properties of bioactive molecules were evaluated to confirm their drug-likeness property. Most of the fifty-eight components are non-toxic and hence this study concludes that only certain sterols, polyphenols, and flavonoids from Fragaria ananassa fruit shows significant effects on erectile dysfunction.
Histochemical Analysis of Plant Raw Materials of Anabasis salsa Growing in the Territory of The Central Kazakhstan
Authors: Itzhanova Kh.I. , Bekisheva P.Zh. , Ishmuratova M.Yu. , Nurmaganbetov Zh. S. , Serikbay A.T. , Poleszak Ewa
Published: September 2024

This article presents results of histochemical analysis of aerial and underground organs of Anabasis salsa (C. A. Mey.) Benth. ex Volkens growing in the Central Kazakhstan. The localization of active substances in medicinal raw materials was determined using histochemical reactions.Presence of essential oil, alkaloids, sesquiterpene lactones, flavonoids, phenolic compounds, polysaccharides in plant organs (shoots, inflorescences and roots) was established. This species is used in traditional medicine as a diuretic, antispasmodic, analgesic, and is also used to treat skin diseases. Purpose of the study: carrying out a histochemical analysis of Anabasis salsa growing in the Central Kazakhstan. Materials and methods: The object of the study is cross sections of shoots and root and surface preparation of Anabasis salsa fruits. Samples of raw materials were fixed in Strauss-Fleming solution, cross sections and surface preparation were prepared manually, after which histochemical reactions were carried out to identify the following biologically active substances: essential oil, flavonoids, alkaloids, polysaccharides and sesquiterpene lactones. Identification of qualitative coloring was carried out by optical microscopy using histochemical tests according to the methods of the State Pharmacopoeia of the Republic of Kazakhstan. Results: The localization of biologically active substances in the studied type of raw material was determined using histochemical methods with light microscopy. The presence of pharmacologically active classes of compounds has been established. Conclusion: For the first time, the localization of secondary metabolites in the plant raw material of Anabasis salsa was studied using histochemical tests. The results of experimental studies can be used to confirm the authenticity, identification and standardization of the aboveground and underground parts of this species.
Chemical Composition and Antioxidant Activities of Spices Essential Oils
Authors: Singh Neetu , Singh Yadav Surender , Narasihman Balasubramanian
Published: September 2024

Oxidative stress is one of the leading causes of several chronic disorders like diabetes, cardiovascular diseases, and cancer. It requires immediate natural measures for its prevention. This can be achieved with natural medicines including spices and their essential oils. Essential oils were extracted from commonly used Indian dietary spices viz. cinnamon, cumin, and Trigonella, and were evaluated for antioxidant activity. Cinnamon and cumin essential oil was extracted using Clevenger apparatus whereas trigonella seed oil was extracted through Soxhlet apparatus. Essential oils were characterized by GC-MS. The% radical scavenging activities of essential oils were assessed using DPPH and ABTS assays. The maximum yield of essential oil (4.35%) was obtained with trigonella seeds through the Soxhlet apparatus. The yield of essential oil extracted through the Clevenger apparatus was 2.75% and 1.53% for cinnamon and cumin, respectively. The presence of various phytocompounds of different essential oils was analyzed by GC-MS. The antioxidant results have shown that the maximum radical scavenging activity was recorded with cinnamon essential oil i.e., 83.82% (DPPH) and 90.54 % (ABTS). Cumin and trigonella essential oils have also shown significant antioxidant activity but were lower than cinnamon essential oil. Cinnamon essential oil exhibited the highest antioxidant activity. This may be attributed to the synergistic effect of its various phytocompounds. Therefore, cinnamon essential oil can be explored further for the development of natural antioxidant compounds.
The effect of Moringa oleifera Leaf Extract Capsules to Anaemia among Post Partum Mothers
Authors: Zainab Zainab , Nurlailah Nurlailah , Khairunisya Siti , Ikhwan Rizki Muhammad
Published: September 2024

Factor that affecting maternal mortality is postpartum haemorrhage due to anaemia and it causes uterine subinvolution. Moringa oleifera leaf from South Kalimantan can be used to treat anemia. The aims of this study were phytochemical screening, determining active ingredients, capsule preparation, cytotoxicity evaluation, and clinical study of Moringa leaf extract capsules. Methods of this study were making the extract of Moringa leaf, followed by phytochemical screening using the tube method and measured active ingredients using a UV-Vis spectrophotometer. The next step was making the extract into capsules and it was tested for toxicity using the BSLT method. Moringa leaf extract capsules were also tested among postpartum women with control and experiment group. The experiment group was given Moringa leaf extract capsules and the control group using iron supplements. We measured hemoglobin and hematocrit pre and post intervention. We used SPSS 23rd version. The study showed that Moringa leaf extract contained flavonoid, phenolic, alkaloid, tannin, saponin, steroid and terpenoid compounds. Moringa leaf extract contained a total phenolic was 13.47% and a total flavonoid was 4.17%. The Moringa leaf extract capsule preparation formula produces capsules in good physical properties and not toxic based on BSLT methods. Clinical trials of Moringa leaf extract capsules in postpartum women showed an increase in hemoglobin and hematocrit levels. In addition, statistical analysis showed significant differences between the control group and the experimental group with Moringa leaf extract capsules.
Intravenous liposomal amphotericin B efficacy and safety for localized cutaneous leishmaniasis: Case series
Authors:   Department of Dermatology, University Hospital, “Renato Dulbecco”, Catanzaro, Italy., Fasano Gaia , D’amico Domenico ,   Department of Dermatology, University Hospital, “Renato Dulbecco”, Catanzaro, Italy., Valenti Giancarlo ,   Department of Dermatology, University Hospital, “Renato Dulbecco”, Catanzaro, Italy.
Published: September 2024

Background: Cutaneous Leishmaniasis (CL) is a skin infection caused by several Leishmania parasites transmitted through sandfly bites, characterized mostly by skin nodules and ulcers in affected individuals. Leishmaniasis is present in the tropical and subtropical temperate areas of the world and throughout the Mediterranean region, particularly in the southern Italian regions such as Calabria and Sicily.
An Analysis of Variations in the Arterial Vascular Pattern of the Right Middle Lobe using Three-Dimensional CT Angiography
Authors:   The First Hospital of China Medical University, No. 155, Nanjing North Street, Shenyang, Liaoning 110002, P.R. China, Xu Shun
Published: September 2024

With the early detection of lung malignant tumors in thoracic surgery, segmentectomy has become a new surgical method in thoracic surgery, which requires thoracic surgeons to have a clear understanding of the structure of the lung segment and blood supply to ensure the smooth operation of the operation.
What happens to aerofoil noise when the aerofoil undergoes flow separation and stall?
Authors: Kim Jae-Wook
Published: September 2024

Aerofoil flow separation and stall is a significant source of self-noise for many engineering applications, particularly when operating at high angles of attack in unsteady inflow conditions. After many years of studies on aerofoil noise, several questions remain regarding both the quantification and physical mechanisms of separation noise.

One of the most fundamental questions yet to be determined is the role of quadrupole sources in contrast with dipoles. The majority of previous aerofoil noise investigations have considered low angles of attack, where the dipole noise generated by a turbulent boundary layer scattered at the trailing edge (TE) is usually considered to dominate the noise production.

However, in the stall regime, the highest intensity flow structures typically appear away from the wall, indicating that the TE will generate sound less effectively. The conventional wisdom that dipole sound should dominate over quadrupole sound may therefore not apply for high angle of attack cases.

This talk provides insight into the role of quadrupole sources due to separated shear layers at low Mach numbers, based on the results of direct numerical simulations.
Les déterminants définis et indéfinis dans la langue malgache : étude comparative avec le français
Authors: HERIMANANA Aina Fanantenana Bertholin Gérard Jocelyn
Published: September 2024

ABSTRACT: This article examines the origin and various influences of the Malagasy language, as well as the specificity of its definite and indefinite determiners in comparison with French. The Malagasy language, rich in a varied linguistic heritage, incorporates elements of Kiswahili, Arabic, Sanskrit, and European contributions. The study focuses on the definition and use of Malagasy definite determiners, particularly their deictic, anaphoric, and cataphoric employment, as well as the unique role of the determiner le-Modif. It also addresses indefinite determiners, defining their usage and analyzing the article ‘un’ accompanied by modifiers. This research contributes to a better understanding of the determination mechanisms in Austronesian languages and sheds light on the interactions between contact languages.
RÉSUMÉ : Cet article examine l’origine et les influences diverses de la langue malgache, ainsi que la spécificité de ses déterminants définis et indéfinis en comparaison avec le français. La langue malgache, riche d’un héritage linguistique varié, intègre des éléments du kiswahili, de l’arabe, du sanskrit et des contributions européennes. L’étude se concentre sur la définition et l’utilisation des déterminants définis malgaches, notamment leur emploi déictique, anaphorique et cataphorique, ainsi que sur le rôle unique du déterminant le-Modif. Elle aborde également les déterminants indéfinis, en définissant leur usage et en analysant l’article un accompagné de modifieurs. Cette recherche contribue à une meilleure compréhension des mécanismes de détermination dans les langues austronésiennes et offre un éclairage sur les interactions entre les langues en contact.
L’intelligence artificielle dans Klara et le Soleil de Kazuo Ishiguro
Authors: EBA Axel Richard
Published: September 2024

ABSTRACT: The central theme in Klara and the Sun is that of Artificial Intelligence. To study it, Julia Kristeva’s semantalysis was useful. The theorist proposes not to be limited to purely textual phenomena so as to be interested in the decryption of analytical categories. Thus, Kazuo Ishiguro under the pivots of pheno-text and geno-text conceptualized his novel as a maieutic of soul of artificial Human.
RÉSUMÉ : Le thème central dans Klara et le Soleil est celui de l’Intelligence Artificielle. Pour en faire l’étude, la sémanalyse de Julia Kristeva a été utile. La théoricienne propose de ne pas se limiter aux phénomènes purement textuels de sorte à s’intéresser au plus haut point au décryptage des catégories analytiques. Ainsi, Kazuo Ishiguro sous les pivots du phéno-texte et du géno-texte a conceptualisé son roman comme une maïeutique de l’âme de l’Homme artificiel.
Impact de l’intelligence artificielle (la traduction automatique) dans l’apprentissage des langues : cas du Tamazight
Authors: GUERCHOUH Lydia , Hakkı Suçin Mehmet
Published: September 2024

ABSTRACT: No field today can do without the assistance of new technologies. Information technology invades all sciences to the great benefit of researchers. While these tools tend to facilitate analyses, they are not without flaws. The use of artificial intelligence in linguistic studies is very recent and struggles to establish itself in methodological practices. Although partially mastered, its use is becoming increasingly frequent. Nowadays, almost all researchers occasionally or regularly resort to machine translation through Google Translate. This website provides translations of texts in several different languages. Our interest through this writing is to review the linguistic constraints and particularities of Tamazight that could affect the reliability of translations and thus assess the possibility of introducing Tamazight among the official languages of Google Translate. Our objective is to suggest preliminary alternatives by leveraging the shortcomings observed in translations into other languages. We aim to highlight translation situations that escape artificial intelligence and require intervention and reformulation of the source or target sentence. Furthermore, we will present the advantages of machine translation in the language learning process compared to other traditional learning systems.
RÉSUMÉ : Aucun domaine ne peut de nos jours se passer de l’assistance des nouvelles technologies. L’informatique envahit toutes les sciences au grand intérêt du chercheur. Si ces outils ont tendance à faciliter les analyses, elles ne sont pas sans failles. L’utilisation de l’intelligence artificielle dans les études linguistiques est très récente et peine à s’installer dans les pratiques méthodologiques. Bien que partiellement maitrisée, son utilisation devient de plus en plus fréquente. De nos jours, presque tous les chercheurs ont occasionnellement ou régulièrement recours à la traduction automatique à travers Google traduction. Ce site web fournit des traductions de textes dans plusieurs langues différentes. Notre intérêt à travers cet écrit est de passer en revue les contraintes et particularités linguistiques du tamazight qui pourraient perturber la fiabilité des traductions et ainsi statuer sur l’éventualité de l’introduction de Tamazight parmi les langues officielles de Google translate. Notre objectif est de suggérer des alternatives en amant en se servant des insuffisances constatées à travers les traductions dans les autres langues. Nous visons à mettre en évidence les situations de traduction échappant à l’intelligence artificielle et nécessitant une intervention et une reformulation de la phrase source ou cible. Par ailleurs, nous exposerons les avantages de la traduction automatique dans le processus d’apprentissage des langues en l’opposant aux autres systèmes d’apprentissage classiques.
Transcreation Flexibility with Hybrid Multilingualism in Algeria
Authors: BELABDI Lalia
Published: September 2024

This study aims to, first, track the origin of multilingualism phenomenon in Algeria, to identify its nature and status to the target audience. Second, it explores the flexibility of transcreation as a sophisticated technique of translation, to provide a baseline understanding of the transcreational act in translation field. In all, the study point uncovers the structural dimensions of translation via transcreation of the hybrid expression. In the theoretical section, the research collects scientific records of transcreation and projects them on the processing of the hybrid expression of multilingual nature by following the qualitative approach. In the practical section, the present study examines the transcreation of advertisements figures where code-mixing and code-switching practices are manifested to express hybrid multilingualism in the Algerian Daridja, as forms of content creation, concretised from the source-idea and the target expression poly-system. The results highlight the importance of understanding the mechanism of the target expression for its impact on the target audience and its capacity of generating content as forms of translation. The creation feature within transcreation technique helps building original contents with maximum flexibility. This study aims to cover the gap of ‘very little is known’ concerning the hybrid multilingualism nature and reality in Algeria, in order to enrich the literature regarding the identifiers of a society that seems somehow undiscovered to Academia folk. Moreover, the study contributes in the stability and the recognition of transcreation as a term and as an operating technique in translation academic studies and practices.
Professional Prospects for Translation / Interpreting Graduates in the Algerian Market
Authors: DAOUD Yasmine
Published: September 2024

Since independence, the Algerian University was among the first universities to propose for students a translation and interpreting degree within the Institute of Translation. Over the years, the Institute has evolved to offer, in addition to the bachelor's degree, a master's and PhD degrees in translation. Once graduated, it is evident that students will try to immerse themselves in a wide-ranging job market. In this regard, we will seek in this article to give an overview of the potential professional opportunities available to students who have recently graduated in the aforesaid discipline, in an Algerian context characterized by the presence on the labor market of salaried translators, official translators, and freelance translators -also called freelancers.
Summary Translation Cognitive Process (Academic Training for Cost-effective Professional Achievement)
Authors: BOUKHEMIS Leila
Published: September 2024

This study aimed to highlight the significance of Summary translation in academic and professional contexts. We introduced a brief definition of other types of translations to make out the dissimilarity, and then we focused on Summary translation within a full process through three samples. The first ones embody professional situations from Public service and Industrial fields of application, the third one is delivered as an academic general text. The aim of this study is to demonstrate the contribution of Summary translation in developing the analytical/synthetical skills of the students through a cognitive process handled by the Interpretive Theory of Translation. The findings determined the significant contribution of a Summary translation in preparing the students to the job market; we also pointed out the behavior of students towards a Summary translation compared to a full transfer, and how to settle any related issue. Accordingly, we proposed a well-structured method to conduct a practical course in the classroom, and we ended by sustaining the use of Summary translation in the job market, for it increases the material and immaterial income of the employers and the employees.
Spatio-topia, Space and Sensation in Joe Sacco’s Footnotes in Gaza
Authors: BEKAKRA Tahani , BENZOUKH Halima
Published: September 2024

The present paper explores the potency of the spatio-topical system of Joe Sacco’s Footnotes in Gaza in (re)tracing the historical events that happened and still happen in the war zone of Gaza without being reductive to the importance of the testimonial culture that is based on listening to and engaging with the different recounts of the Gazan survivors from the 1956 Khan Younis and Rafah killings and the present horrible moments of destruction, dispersion and oppression. For this purpose, this paper embraces Thierry Groensteen’s concept of ‘spatio-topia’ that denotes the systematic distribution of the space on the graphic page in order to give the graphic aesthetic, the driving force of reading. Therefore, graphic spatio-topia configures the conceptual form of the story world that allows the reader to participate spatially and sensationally in Sacco’s journalistic investigations through its different tools like the panel and its frame with their spatio-topical parameters of the form, the seize and its site. The systematic operativity of the graphic spatio-topical elements of Footnotes in Gaza promotes a flexible and a meaningful flow of the graphic narrative and transports the reader to the graphic space where he develops a spatialized history and a dense web of sensations like belief and pain.
Discourse as an Essentially Contested Concept in Media Studies: From the Correct Use to the Abstract Concept
Authors: BOUIFER Abdelhak , KADEM Djamila
Published: September 2024

The issue of concepts formation has always been at the centre of debate among scholars in media and communication studies. This paper is an attempt to introduce the general principles of Gallie's essentially contested concepts in the light of the widespread use of concept misunderstanding in this field of research where discourse is of central importance to researchers. We argue that the present essay explores primarily the option of placing more attention on theorizing rather than on theory. Accordingly, this article does seek to address the concepts of discourse in the established schools of discourse analysis within Gallie's framework aiming at settling the conflict over discourse by constructing epistemological bridge with Sartori's ladder of abstraction to overcome the problem of essential contestedness in media and communication studies.
دور المقاربة النصية في تجاوز صعوبات التعلم وتحقيق التمرس اللغوي
Authors: BENSEGHIR Karima , HAMDI BACHA Yasmine , SOLTANI Farouk
Published: September 2024

ABSTRACT: This study aimed to highlight the textual approach, which emerged in conjunction with the competency approach, in light of the general context of the education system, which has experienced several educational reforms, and tried through it to overcome the gaps left by the previous approaches. Thus, it made the textual approach a learning method for presenting the text, in order to extract from the learning process features that appear at the end of each educational phase, resulting in an improvement in the linguistic faculty of the learner, proficient in reading and writing.
الملخص:  سعينا في هذه الورقة العلمية لتقديم رؤية عن المقاربة النصية، التي تزامن ظهورها مع انتهاج المقاربة بالكفاءات، في ظل سياق عام عرفته المنظومة التربية، التي شهدت عدة إصلاحات تربوية، سعت من خلالها لتجاوز الثغرات التي خلفتها المناهج السابقة، فجعلت من المقاربة النصية طريقة تعلمية لتقديم النص، حتى تحقق من العملية التعلمية ملامح تخرج في نهاية كل طور تعليمي، ينجر عنها تحسن في الملكة اللغوية للمتعلم، يتقن استخدامها قراءة وكتابة.
Reactions on 5G Phone, Cable, and Broadband Internet Preceding X
Authors: Moore Nathan M.
Published: September 2024

Finalizing a report on the findings of my Twitter research study effectively documented how recipients of a poll survey reacted to questions about 5G. Reactions in the form of emoji likes and comments are only a minutia of social media’s reach. The research question I used was: in what ways has 5G service affected your perception of cell phone carriers, cable, and internet providers since its inception? To answer that question accurate data had to be found utilizing a methodology known as sentiment analysis. As in any good academic research proposal, technical communication research methods must evolve to incorporate both machine learning and organic approaches. I hypothesized that by conducting manual Twitter polls to elicit responses it would provide enough organic information to rival the most robust AI-based sentiment analysis on how 5G was being branded in the marketplace for social media users. To fulfill my goal, I wanted to find out several important changes that had occurred since 2017; cell phone manufacturers’ production; cell phone buyers’ habits toward the same products; and the behaviors of customers who bought 5G concerning the older 4Glte band of phones or internet. Triangulation of Twitter data and sampling a general community, including using mixed research methods, would give enough empirical data. Between the strong opinions and lesser ones, seeing where there was parity in the research results codified a ubiquitous classification system needing modification.
Exploring program death-1 and cytotoxic T lymphocyte antigen-4 safety in gastric cancer clinical trials: A meta-analysis
Authors: Theophilus Acquah , Wang Yahui , Da Wenxin , Xu Yang , Li Qiu , Chen Zhihong , Ma Jie , Shaibu Zakari
Published: September 2024

Background: Gastric cancer is one of the leading causes of cancer-related deaths worldwide. Despite advances in treatment options, the overall prognosis for advanced gastric cancer remains poor. Immunotherapy has revolutionized the field of cancer treatment by harnessing the patient’s immune system to target and destroy cancer cells. Two important immune checkpoint inhibitors that have shown promise in various malignancies, including gastric cancer, are program death-1 and cytotoxic T lymphocyte-4 inhibitors.

Aims: To assess and analyze the occurrence of adverse events associated with program death-1 and cytotoxic T lymphocyte antigen-4 in patients diagnosed with advanced gastric cancer.

Methods: Relevant studies were searched in reputable databases such as PubMed, Embase, Google Scholar, and the Cochrane Library from October 6, 2017, to February 3, 2022. Studies were analyzed with Review Manager 5.4. PROSPERO: CRD42023479662.

Results: Of the 500 studies retrieved, nine randomized control trials involving 5,185 patients were included in the meta-analysis comparing TRAEs in advanced gastric cancer patients after immune checkpoint inhibitor monotherapy and combined immune checkpoint inhibitors treatment. There was a lower risk of any grade of treatment-related adverse events with program death -1 than in the control arm (76.5% vs. 79%, P = 0.02). Program death-1 observed a lesser risk of grade 3-4 treatment-related adverse events as compared to the control for nausea (0.3% vs. 3%, P = 0.007) and fatigue (1% vs. 2.7%, P = 0.006). Program death-1 monotherapy also saw a decrease in the incidence of common treatment-related adverse events such as diarrhea (9.6% vs. 16%, P < 0.00001), nausea (6.8% vs. 20.6%, P < 0.00001) and fatigue (11% vs. 15.9%, P = 0.001). However, pruritus occurrence increased (3.8% vs. 9%, P < 0.001) after program death-1 compared to control.

Conclusions: Patients with advanced gastric cancer endured program death-1 treatment effectively. Nonetheless, the combination of program death-1 and cytotoxic T lymphocyte-4 results in a greater occurrence of treatment-related adverse events.
Thermal stress response in the Montastraea cavernosa coral-symbiont complex in the Mexican Caribbean, through the expression of the HSP70 gene
Authors: Colín-García Norberto A , Ocaña-Mendoza Camila , Chiappa-Carrara Xavier , Rioja-Nieto Rodolfo , Arena Ortíz M Leticia , Calle-Triviño Johanna , Alvarado-Recillas Natalia , Campos Jorge E
Published: September 2024

Coral reefs are under constant and increasing environmental stress. Symbiotic relationships between coral and dinoflagellates of the family Symbiodiniaceae help corals resist stressors and survive. Therefore, it is essential to implement conservation and restoration programs that use
genetic diversity and response mechanisms at the molecular level of corals and their symbionts. This study assessed the thermal stress response through the expression of the heat shock protein 70 (HSP70) in Montastraea cavernosa corals and their symbionts from the Mexican Caribbean.
We observed variation in the expression level and that corals have high HSP70 levels, while symbionts exhibit low HSP70 values. Additionally, the ability of the symbiont to acclimatize to thermal stress conditions is evident, which may allow the coral to resist environmental stressors; a joint
response in both host and symbionts can also reduce cell damage and prevent bleaching. Detecting and spreading stress-resistant organisms can enhance coral reef restoration by reducing bleaching, mortality, and promoting adaptive genes.
Rezension von: von Andrian-Werburg, Klaus (Bearb.), Die Urkunden des Schlossarchivs Kronburg
Authors: Lenckner Georg , Andrian-Werburg Klaus von
Published: September 2024

Die Urkunden des Schloßarchivs Kronburg 1366-1829. Bearbeitet von Klaus Freiherr von Andrian-Werburg. (= Schwäbische Forschungsgemeinschaft 2 a, Bd. 8.) Augsburg 1962. 320 S.
Rezension von: Dienel, Werner Martin (Hrsg.), Wo Kocher, Jagst und Tauber fliessen
Authors: Lenckner Georg , Dienel Werner Martin
Published: September 2024

Werner Martin Dienel: Wo Kocher, Jagst und Tauber fließen. Ein Hohenloher Heimatbuch. Gerabronn 1963. 220 S. 12,80 DM.
Rezension von: Ulshöfer, Kuno, Die Geschichte des Klosters Schäftersheim
Authors: Lenckner Georg , Ulshöfer Kuno
Published: September 2024

Kuno Ulshöfer: Die Geschichte des Klosters Schäftersheim. Mergentheim 1963. 186 S.
Rezension von: Uhland, Robert (Hrsg.), Lebensbilder aus Schwaben und Franken, 8
Authors: Schwarz Paul , Uhland Robert
Published: September 2024

Lebensbilder aus Schwaben und Franken. Im Auftrag der Kommission für geschichtliche Landeskunde in Baden-Württemberg herausgegeben von Max Miller und Robert Uhland. Bd. 8. Stuttgart: Kohlhammer 1962. 391 S. 19,50 DM.
Rezension von: Zeitschrift für württembergische Landesgeschichte, Jg 21.1962
Authors: Wunder Gerd
Published: September 2024

Zeitschrift für württembergische Landesgeschichte 21, 1962. 449 S.
Covid-19 in child health and nutrition: exploring relationships between anthropometric indicators and food and nutrition insecurity
Authors: Maciel Kleslene , Mota Amanda , Barbosa Janaina Maiana , Rêgo Adriana , Chagas Maria Raimunda , Falcai Angela , Dos Santos Alexsandro
Published: September 2024

This is an analytical cross-sectional study with the objective of evaluating immunization associations, anthropometric indicators and food and nutritional insecurity in 100 children treated at a Basic Health Unit in São Luís-Maranhão. Sociodemographic data, anthropometry, vaccination data and the Brazilian Food Insecurity Scale were collected. Stata® 14.0, chi-square tests and binary logistic regression were used at a significance level of 5%. There was a predominance of adequate weight for age (85,1%), adequate height for age (99%) and high BMI-for-age (75%), with 34.4% of severe cases. The results show statistically significant associations (p < 0.05) for sociodemographic variables (income), social and health data (access to government benefits and basic food basket) and clinical and immunological data (COVID infection for parents and children), which are considered determining factors in the increase in IAN.
Beyond right or wrong: towards redefining adaptive learning indicators in virtual learning environments
Authors: Sachete Andréia dos Santos , Loiola Alba Valéria de Sant’Anna de Freitas , Rossi Fábio Diniz , Lima José Valdeni de , Gomes Raquel Salcedo
Published: September 2024

Student learning development must involve more than just correcting or incorrect questions. However, most adaptive learning methods in Virtual Learning Environments are based on whether the student's response is incorrect or correct. This perspective is limited in assessing the student's learning level, as it does not consider other elements that can be crucial in this process. The objective of this work is to conduct a Systematic Literature Review (SLR) to elucidate which learning indicators influence student learning and which can be implemented in a VLE to assist in adaptive learning. The works selected and filtered by qualitative assessment reveal a comprehensive approach to assessing different aspects of the learning in virtual environments, such as motivation, emotions, physiological responses, brain imaging, and the students' prior knowledge. The discussion of these new indicators allows adaptive technology developers to implement more appropriate solutions to students' realities, resulting in more complete training.
Flush plus application for evaluation of reproductive efficiency of bovine females
Authors: Spers Rodolfo Cláudio , Marcondes Otavio Gasparini Marcondes , Peternelli Leticia Peternelli , Del Carratore Carlo Rossi Del Carratore , Bueno Patricia Cincotto dos Santos Bueno , Costa Isabela Bazzo da Costa , Spers Márcio José Segateli Spers
Published: September 2024

Nutrition affects all events of the reproductive cycle, from gametogenesis to puberty, in both males and females. The reason for such dependence is to ensure that the reproductive cycle is synchronized with the nutritional supply, ensuring the success of lactation and growth of the newborn, phases that are especially demanding in terms of energy. Hence the fact that cattle have a physiological mechanism that limits reproduction to 15 months on average, making the birth season favorable to survival. However, this does not always mean that this season is the most commercially favorable for the producer, and although in nature the synchronization between reproductive activities and nutritional seasonality is a critical and essential factor for survival, when it comes to commercial herds this relationship represents yet another risk to productive efficiency. That is why flushing - a nutritional increase in the weeks before the start of the mating season - has been widely used. To obtain the best results with flushing, we must have an idea of ​​the animal's energy balance - when the nutritional needs of cattle are greater than what they are ingesting, they will have to use their energy stores (glycogen, triglycerides and protein) to fill this gap - we say that this animal is in a negative energy balance. This application will need the following information: 1- Selection of Primiparous and Multiparous Animal Category 2- Quantity and type of supplement provided. 3- Period of supply (days and weeks) 4- Evaluation of the Collection of results 5- Size and vigor... etc.... 6- Results: % improvement and/or reproductive efficiency. The present work will develop the practical application that will help the cattleman in evaluating the efficiency of the fhushing technique in the reproductive improvement of bovine.
O brutalismo na arquitetura brasileira e sua infuência no Campus Darcy Ribeiro
Authors: Stefani Dall Agnol Bruna , Da Costa Pantoja João , Gomes Cardoso Pedro , Stella Silva Menezes Érika
Published: September 2024

O estudo visa discorrer sobre a influência arquitetônica do brutalismo na idealização de Brasília e do Campus Darcy Ribeiro da UnB, permeando o surgimento do brutalismo na Europa pós-Segunda Guerra, como ele influenciou arquitetos modernistas brasileiros e como essa influência moldou obras icônicas no Brasil. No Brasil, essa tendência foi adotada por João Batista Vilanova Artigas e Paulo Mendes da Rocha. No Campus Darcy Ribeiro da UnB, a influência brutalista se manifesta na racionalidade e na robustez das edificações, integrando a estética do movimento com a funcionalidade requerida por um ambiente educacional. Se utilizando de livros, revistas, entrevistas e outros artigos científicos, os dados coletados foram organizados de forma que contassem uma história iniciada no surgimento do brutalismo como conceito e estética até sua influência no Campus Darcy Ribeiro. Este estudo não apenas explora a evolução do brutalismo, mas também destaca sua importância no contexto brasileiro, reforçando a necessidade de preservar e compreender essas contribuições arquitetônicas para as gerações futuras.
Aplicações sustentáveis do aproveitamento de subprodutos do processamento do pinhão
Authors: De Rocco Camila , Silvestro Goulart Ivan , Tiecher Marin Aline , Rosset Michele
Published: September 2024

O objetivo deste estudo foi conduzir uma revisão sistemática da literatura para descrever aplicações sustentáveis do aproveitamento de subprodutos do processamento do pinhão, especificamente a casca do pinhão. As buscas foram realizadas nas bases de dados Scielo, Pubmed e Science Direct e o termo utilizado foi “pine nut shell", mediados pelo operador boleano AND e compreenderam o período de Janeiro de 2019 a Maio 2024. Foram encontrados um total de 2.765 estudos nas referidas bases de dados e no final 10 artigos foram incluídos nos resultados da presente revisão sistemática. Os principais achados indicam que a casca de pinhão pode ser inserida em diferentes áreas de reutilização, como produção de filtros fluviais, embalagem filme de quitosana comestível, produção de poliuretano, produção de carbono poroso e ainda pode ser utilizado como componente funcional para formulação de produtos alimentares desportivos. Sendo assim, conclui-se que a reutilização da casca de pinhão, considerada um resíduo, pode ser um potencial subproduto a ser utilizado para produção de inúmeros itens a serem explorados no comércio, influenciando aplicações sustentáveis.
A vulnerabilidade do consumidor na hipermodernidade: perpsectivas da ética artistotélica e justiça nas relações de consumo e na estetização da vida
Authors: Nascimento Cleber Augusto do , Oliveira Cristiane Santos
Published: September 2024

O artigo aborda a vulnerabilidade do consumidor na sociedade hipermoderna, destacando a orientação do mercado, especialmente o da estética e saúde, ao consumo no sentido de uma busca por uma felicidade artificial e inatingível. Além disso, investiga a aplicação dos princípios da ética aristotélica, especificamente os conceitos de amizade e felicidade presentes na "Ética a Nicômano", para fundamentar a noção de boa-fé nas relações de consumo. O foco recai sobre os conceitos de amizade (philia) e felicidade (eudaimonia), fundamentais na filosofia   aristotélica. A aplicação desses conceitos aristotélicos pode redefinir as práticas consumeristas. Finalmente, sugere-se que a adoção de uma abordagem ética nas relações de consumo, influenciada pelo pensamento aristotélico, pode contribuir para a redução da vulnerabilidade do consumidor e para o estabelecimento de práticas comerciais mais justas e humanizadas. Destaca-se que tal abordagem não apenas protege os consumidores, mas também promove um modelo de negócios sustentável e ético.
Automedicación con antiinflamatorios no esteroideos y factores asociados en universitarios de Lima en el 2023
Authors: Estrada Ancajima Carla
Published: September 2024

Objetivos:  Determinar los factores asociados a la automedicación con antiinflamatorios no esteroideos en universitarios de Lima en el año 2023. Materiales y métodos: Estudio observacional, analítica, transversal y prospectivo. La población estuvo conformada por 200 estudiantes y la muestra por 170. Se empleó una encuesta virtual para la recolección de datos. Resultados: Se encuestó a un total de 170 estudiantes. El 38,8% de la población estudiada se automedica. El 60,6% de las mujeres y el 48,5% de los mayores de 25 años son los que recurren a la automedicación. El AINE más usado para tratar el dolor es el paracetamol con un 62,2%, en tabletas y cápsulas. El 36,5% de los estudiantes suele ir al hospital. Un 29,4% de los participantes no tiene conocimiento sobre la dosis del medicamento que consume. En los factores asociados, los sociodemográficos y los factores personales no estuvieron relacionados. Dentro de los factores culturales, el consumir actualmente AINES y que sean genéricos o de marca están asociados a la automedicación (OR: 1,028, IC95%: 0,552 – 1,914; p= 0,007) (OR:2,813, IC95%: 1,342 – 5,894; p= 0,005). Conclusiónes: Se concluye que los universitarios de Lima se automedican. El factor cultural está asociado a esta práctica.
Menemukan Self Insight Melalui Coaching dengan Teknik Point of You Bagi Para Guru PKBM Al Qalam Citra Indah Bogor
Authors: Khairunnisa Khairunnisa , Arini Dewi Ulfah
Published: September 2024

Kegiatan pengabdian kepada masyarakat dilaksanakan dengan tujuan untuk membantu para guru di lingkungan Al Qalam Citra Indah dalam menemukan pemahaman yang lebih mendalam tentang diri mereka sendiri melalui metode coaching. Dengan memanfaatkan teknik Point of You, para peserta diharapkan dapat mengidentifikasi potensi, kekuatan, dan area yang perlu dikembangkan dalam diri mereka. Metode yang digunakan dalam kegiatan ini melibatkan sesi coaching berbasis kelompok, di mana setiap kelompok terdiri dari 2 kelompok orang guru. Para peserta diajak untuk melalui proses refleksi yang dipandu oleh fasilitator, menggunakan alat visual sebagai stimulus untuk mengeksplorasi berbagai perspektif. Hasil dari kegiatan ini menunjukkan bahwa setiap kelompok berhasil menemukan wawasan baru mengenai diri mereka, dengan peserta melaporkan peningkatan kepercayaan diri dan motivasi. Secara keseluruhan, para guru mendapatkan manfaat signifikan dari kegiatan ini, termasuk kemampuan untuk lebih memahami diri mereka sendiri, serta kesiapan untuk mengaplikasikan wawasan yang diperoleh dalam konteks pengajaran. Kegiatan ini menekankan pentingnya keterlibatan aktif para guru dalam proses pengembangan diri, yang berdampak langsung pada kualitas pendidikan di komunitas mereka.
Contencioso estrutural sobre o Acordo de Paz na Colômbia: reflexões sobre o habitus das instituições políticas e judiciais
Authors: Rodríguez Michael Cruz
Published: September 2024

Com base na análise dos cenários de litígio estrutural gerados em relação à implementação do Acordo Final de Paz na Colômbia, argumenta-se que as instituições políticas e judiciais incorporaram práticas (habitus) típicas do monitoramento rotineiro do Tribunal Constitucional dos Estados de Assuntos Inconstitucionais (ECI). Enquanto as instituições judiciais reproduzem estas práticas, duplicando mesmo a monitorização, as instituições políticas reiteram respostas sem uma resposta substantiva, a fim de cumprir por não cumprir. Como resultado, os problemas estruturais permanecem no âmbito do discurso jurídico e a materialização dos direitos é atrasada e adiada indefinidamente.
El virus, los procesos de digitalización-virtualización en América Latina y perspectivas de una recuperación sustentable
Authors: Ordóñez Sergio , Vidals Noé
Published: September 2024

Es posible hablar de una “economía política del virus” para referirse a la realidad económica y política mundial en la cual el virus emerge, además de la forma en que éste incide sobre sus principales tendencias de desarrollo. En esa perspectiva, el principal legado es un salto mundial “espontáneo” en los procesos de digitalización-virtualización, el cual se dio en un contexto geoeconómico-político mundial de una profundización de la disputa entre China y Rusia, por una parte, y Estados Unidos, por la otra, durante la propagación del virus. En América Latina, este contexto evidenció el rezago en el desarrollo de la industria de servicios de telecomunicaciones como soporte de los procesos de digitalización-virtualización. Con base en lo anterior, se argumenta que el salto en América Latina fue de una importancia relativa considerable, al abrir un horizonte de posibilidad para una recuperación sustentable, a partir de un accionar extendido del Estado que profundice ese salto teniendo como eje el desarrollo de la industria de servicios de telecomunicaciones e incorporando la dimensión ecológica de los procesos de digitalización-virtualización y tecnologías asociadas, para posicionar a la región en la transición energética en curso, aprovechando en su favor la disputa hegemónica mundial para promover mayores procesos de autodeterminación.
Análise comparativa das emissões de gases de efeito estufa nas regiões do SEALBA e MATOPIBA
Authors: Suela Attawan Guerino Locatel , Suela Gabriel Locatel , Bogdezevicius Carlos Rafael , Fontes Ana Taís Muniz , Almeida Edinael Rodrigues de
Published: September 2024

A crescente demanda por alimentos e biocombustíveis tem levado à expansão agrícola em regiões brasileiras como MATOPIBA e SEALBA, resultando em sérios impactos ambientais, incluindo o desmatamento e o aumento das emissões de gases de efeito estufa (GEE). Este estudo analisa as emissões de GEE na região do SEALBA, comparando-as com as já documentadas no MATOPIBA, que teve intensa atividade agropecuária nas últimas três décadas. A pesquisa utilizou dados de emissões obtidos pela plataforma SEEG para os anos de 2000 a 2022. A análise mostrou que ambas as regiões seguem tendências semelhantes, com aumento das emissões decorrentes da agropecuária e mudanças no uso da terra. No SEALBA, a expansão agrícola, particularmente para a produção de soja e pecuária, tem elevado as emissões, refletindo um cenário preocupante observado anteriormente no MATOPIBA. A comparação entre as duas regiões sugere que, sem políticas de mitigação eficazes, o SEALBA poderá enfrentar desafios ambientais semelhantes aos do MATOPIBA. O estudo também aponta a necessidade de estratégias regionais específicas para controlar o desmatamento e as emissões, levando em consideração as particularidades de cada área, como a significativa contribuição da Bahia para as emissões totais. Essas conclusões podem orientar a formulação de políticas públicas que promovam a sustentabilidade na expansão agropecuária.