bluuebunny/crossref_metadata_2025 huggingface dataset:
Occupational Injuries in Civil Aviation
Authors:   Moscow State Technical University of Civil Aviation (MSTU CA), Nikolaykin N.I. , Merzlikin I.N. ,   Moscow State Technical University of Civil Aviation (MSTU CA), Sigaleva E.E. ,   IMBP RUS, Stepanova G.P. ,   IMBP RUS
Published: January 2024

Statistical data on the Russian occupational injuries over two decades indicate a reduction in the victims annual number in all the sectors of the country economy from more than 150 thousand employees per year (2000) to 20 thousand (2021). It is shown that the number of fatal accidents during the same time decreased from 4.4 thousand per year to 1 thousand. The authors argue that during the aircraft ground maintenance in civil aviation, the cases of injury to employees and occupational diseases occur in accordance with what happens at the industrial enterprises. Statistics on monitoring working conditions and injury incidents at the aviation enterprises over the past three decades (excluding those injured in aviation accidents) are presented. Based on monitoring data, it is shown that in the period from 2000 to 2021, the rate of decline in the number of employees affected by industrial hazards in civil aviation is approximately 1.5 times higher than the same figure for the country. The results of a statistical analysis of the employee injury causes cases that occurred are described. It is stated that the working conditions characteristic feature of the employees at enterprises and organizations of the country during the period of time under consideration was and remains increased noise levels in the workplaces. At the civil aviation enterprises, the share of people employed in work with such harmful and (or) hazardous working conditions as noise, ultrasound, and infrasound the last decade is about 20 % over. The review is provided concerning the modern methods for reducing the impact of noise on the employees conducting aircraft ground handling operations. Recommendations are given on improving methods for counteracting the noise negative effects, developing personal protective equipment for areas of high noise pollution, and for further research.
Inspection of Hidden Areas of Small-diameter Steel Pipes using Ultrasonic Flaw Detection
Authors:   Bauman Moscow State Technical University, Shchipakov N.A. ,   Welding and Testing Scientific-Educational Center at the Bauman Moscow State Technical University, Krysko N.V. ,   Bauman Moscow State Technical University,   Welding and Testing Scientific-Educational Center at the Bauman Moscow State Technical University, Kusyy A.G. ,   Bauman Moscow State Technical University,   Welding and Testing Scientific-Educational Center at the Bauman Moscow State Technical University
Published: January 2024

According to the current regulatory documents, as the established service life of gas pipelines for various purposes expires, they must be inspected in order to assess the current technical condition, make a decision on the residual life and the possibility of further operation at hazardous production facilities, as well as other buildings and structures. The possibility is considered related to using ultrasonic testing for detecting damage of corrosion origin in the sections of such pipelines hidden from the direct observation in interfloor ceilings and passages through the walls of buildings at the facilities in various branches of industries, as well as in gas distribution and gas consumption systems, and water pipelines. In addition, the possibility of identifying layered deposits of various origins in the cavity of small-diameter steel pipes is considered. At energy facilities, as well as in water supply pipelines, such deposits can lead to a significant reduction in the flow area of the pipeline, up to its complete blocking. Deposits inside the pipelines form an anisotropic layered medium, and the passage of ultrasonic waves through it has a number of features that prevent the use of traditional ultrasonic echo testing. For small-diameter pipes, the criterion is given under which it is possible to perform «remote» (waveguide) ultrasonic testing of the hidden sections of pipes at a distance of up to 600 mm. It is illustrated how, from such a distance, it is possible to detect corrosion deposits in pipes by ultrasonic testing methods using phased array antennas. At the same time, it is possible to assess the thickness («power») of layered deposits and their structure even when the passage section of the pipeline is filled with such deposits up to 100 %. Use of the methods presented in the article allows to increase the accuracy of calculating the residual life of the pipeline and reduce the uncertainty in setting safety factors in such calculations.
Law Enforcement Practice of the Occupational Safety Training Rules
Authors:   Federal State Budgetary Institution «All-Russian Research Institute of Labor» of the Ministry of Labor and Social Protection of the Russian Federation, Tsirin I.V.
Published: January 2024

The article examines the possible correlation between the rates of fatal occupational injuries and the implementation of mandatory requirements for training employees in occupational safety. Retrospective analysis of the scope of occupational safety training was conducted. The results of filling out registers in the new model for recording trained people were systematized. Significant changes in the structure of the contingent of trained people was identified. A significant increase in training volumes was established. An assessment was made of the influence of changes in the legal regulation associated with the entry into force of the new Rules for training in occupational safety and testing knowledge of the occupational safety requirements on the planning, organization and conduct of training in occupational safety. The law enforcement practice of the new rules is analyzed. A forecast hypothesis was formulated that the unconditional application of the mandatory requirements of these rules when planning, organizing and conducting occupational safety training will lead to a change in the rate of reduction in the occupational injuries, including fatalities.
New Requirements for Certification in the Field of Industrial Safety
Authors:   STC «Industrial Safety» CJSC, Gontarenko A.F. ,   Federal State Budgetary Institution «All-Russian Research Institute of Labor» of the Ministry of Labor and Social Protection of the Russian Federation, Klovach E.V. ,   STC «Industrial Safety» CJSC
Published: January 2024

An overview is provided related to the main changes in the procedure for conducting certification of managers and specialists in the field of industrial safety. These changes are due to the entry into force on September 1, 2023 of the requirements of the Government of the Russian Federation of January 13, 2023 № 13 «On certification in the field of industrial safety, on the issues of safety of hydraulic structures, safety in the electric power industry» and the termination of the requirements of the Russian Federation Government Decree dated October 25, 2019 № 1365 «On training and certification in the field of industrial safety, on the issues of safety of hydraulic structures, safety in the electric power industry». The changes in the field of certification establish: exclusion of certain categories of employees from the number of persons required to receive additional professional education in the field of industrial safety and undergo certification in industrial safety at least once every five years; the categories of employees who undergo certification exclusively in the certification commissions of the organizations operating in the field of industrial safety; expanding the list of information provided by the applicant for certification in the territorial certification commission of Rostechnadzor; the procedures in case of force majeure circumstances preventing the presence of the certified person during certification in the territorial certification commission of Rostechnadzor; the requirements for computer testing as part of industrial safety certification; the procedure for filing and consideration in the central certification commission of Rostechnadzor of appeals against a decision, action (inaction) of the territorial certification commission of Rostechnadzor; the procedure for entering information on the results of certification in the Rostechnadzor certification commissions and the certification commissions of organizations into the register of the certified persons, as well as cases of exclusion of information from this register; adjustment to reduce the time required for completing procedures as part of Rostechnadzor provision of state services for organizing certification in the field of industrial safety.
Planar Microwave Sensor with High Sensitivity for Material Characterization Based on Square Split Ring Resonator (SSRR) for Solid and Liquid
Authors: Maizatul Alice Meor Said  , Zahriladha Zakaria  , Mohamad Harris Misran  , Mohd Azlishah bin Othman  , Redzuan Abdul Manap  , Abd Shukur bin Jaafar  , Shadia Suhaimi  , Nurmala Irdawaty Hassan
Published: January 2024

Microwave resonator sensors are the most extensively used sensors in the food industries, quality assurance, medical, and manufacturing. Planar resonant technique is chosen as the medium for characterizing dielectric properties of material due to its compact in size, low cost and easy to fabricate. But these techniques have a low Q-factor and little sensitivity. This work uses the perturbation approach to overcome this technique's flaw, which is that Q-factor and resonant frequency are affected by the resonator's dielectric properties. This suggested sensor operated at 2.5GHz between 1GHz and 4GHz for material characterisation of solid and liquid samples. These sensors were constructed on a substrate made of RT/Duroid Roger 5880, which has a copper layer that is 0.0175 mm thick and has a dielectric constant of 2.2. This square split ring resonator (SSRR) sensor thus generates narrower resonant, low insertion loss, and a high Q-factor value of 430 at 2.5GHz. The SSRR sensor's sensitivity is 98.59%, which is higher than that of past studies. The application of the suggested sensor as a tool for material characterisation, particularly for identifying material attributes, is supported by this findings.
Development of a Mobile Application for Plant Disease Detection using Parameter Optimization Method in Convolutional Neural Networks Algorithm
Authors: Alwan Fauzi  , Iwan Syarif  , Tessy Badriyah
Published: January 2024

Plant diseases are a serious problem in agriculture that affects both the quantity and quality of the harvest. To address this issue, authors developed a mobile software capable of detecting diseases in plants by analyzing their leaves using a smartphone camera. This research used the Convolutional Neural Networks (CNN) method for this purpose. In the initial experiments, authors compared the performance of four deep learning architectures: VGG-19, Xception, ResNet-50, and InceptionV3. Based on the results of the experiments, authors decided to use the CNN Xception as it yielded good performance. However, the CNN algorithm does not attain its maximum potential when using default parameters. Hence, authors goal is to enhance its performance by implementing parameter optimization using the grid search algorithm to determine the optimal combination of learning rate and epoch values. The experimental results demonstrated that the implementation of parameter optimization in CNN significantly improved accuracy in potato plants from 96.3% to 97.9% and in maize plants from 87.6% to 93.4%.
THE IMPACT OF SI AND QCL ON STUDENT PERFORMANCE IS MODERATE BY STUDENT CULTURE
Authors: Kusuma Emeralda Ayu , David David Efendi
Published: January 2024

Spiritual intelligence and the quality of campus life are interesting to study in contributing to student performance. This research aims to (1) analyze and prove empirically the impact of spiritual intelligence on student performance, (2) analyze and prove empirically the influence of campus life on student performance, (3) analyze and prove empirically the moderation of student culture on the influence of spiritual intelligence on student performance, and (4) empirically analyze and prove the moderation of student culture on the influence of the quality of campus life on student performance. Therefore, the research used mixed qualitative and quantitative descriptive-analytical methods with an active student analysis unit of 96 respondents at private higher schools in East Java. The analytical tools were descriptive statistics, validity tests, reliability tests, classical assumption tests, and regression analysis. As the results, the research found that (1) spiritual intelligence had no effect on spiritual performance, (2) the quality of campus life had no effect on student performance, (3) student culture negatively moderated or weakened the effect of spiritual intelligence on student performance, and (4) culture students could not moderate the impact of the quality of campus life on student performance.
Penguatan Moderasi Beragama dalam Perspektif Politik di Kabupaten Kotawaringin Timur
Authors: Gofur Abdul , Wahid Abdul , Napisah Nur
Published: January 2024

Tujuan dari penelitian ini adalah mendeskripsikan penguatan moderasi beragama melalui pendidikan politik di Kabupaten Kotawaringin Timur. Penguatan ini dilakukan melalui dua kegiatan oleh Badan Kesatuan Bangsa dan Politik (Kesbangpol) dan Forum Kerukunan Umat Beragama (FKUB). Jenis penelitian menggunakan penelitian kualitatif dengan pendekatan deskripstif kualitatif. Teknik pengumpulan data menggunakan wawancara dan dokumentasi. Teknik analisis data melalui tahapan berupa: pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Pada hasil penelitian didapatkan data bahwa penguatan moderasi beragama di Kabupaten Kotawaringin Timur dilakukan atas kerjasama antar lembaga pemerintah maupun non pemerintah, elemen masyarakat dan organisasi kemasyarakatan (ormas). Penekanan dilakukan terhadap penanaman nilai-nilai toleransi dalam berpolitik melalui; menghormati pilihan masing-masing individu didalam pemilu, menghindari praktik kecurangan maupun terlibat di dalam politik uang, praktik penggunaan hak pilih, berserikat dan berkumpul tanpa adanya intervensi dari pihak manapun, persamaan terhadap hak-hak setiap warga negara dalam berpolitik dan perubahan sikap mental generasi muda. Pengembangan konsep moderasi beragama di kota ini perlu dilihat lagi keefektifan di tengah masyarakat.
Implementation of Problem-Based Learning Model based on Differentiated Learning to Improve Science Literacy Skills and Student Activities
Authors: Dewi Virlya Citra , Kuswanti Nur , Prijono Bambang
Published: January 2024

Scientific literacy skills are a person's ability to understand and construct scientific concepts so that they can apply them scientifically to respond to environmental issues and solve their problems. This skill is essential to train students so that students are more involved and active in learning. The low level of scientific literacy skills and student activity is a problem that is often faced by Indonesian teachers. This study aims to improve scientific literacy skills and student activity through problem-based learning based on a differentiated learning approach. This type of research is Classroom Action Research (CAR), which consists of four stages: planning, action, observation, and reflection. Data collection techniques in this study are observation and tests. The research instrument was an observation sheet to determine student learning activities, while a test sheet was used to determine students' literacy skills. Based on the study's results, it showed an increase in scientific literacy skills and student activity in each cycle. This can be seen from the N-gain value of the first cycle (0.63) and the second cycle (0.71), and the average of student activity in the first cycle (70.32%) and the second cycle (88.44%). Thus, it can be concluded that the implementation of problem-based learning based on a differentiated learning approach can improve scientific literacy skills and student activity.
Needs Analysis to Develop Physics Learning E-Modules on Static Electricity Material
Authors: Nilyani Korry , Anjani Hilmi Rizki , Desnita Desnita , Usmeldi Usmeldi
Published: January 2024

Science and technology continue to experience developments in education at the school level, giving rise to demands and improvements in the learning process. In the 21st century, students need the right learning resources in order to understand the lesson well. It is necessary to do a needs analysis to develop learning media. This study aims to analyze the need for e-module development for physics learning. The urgency of this research is due to the difficulties faced by students in understanding physics concepts and solving physics problems. The problem discussed in this study is the need for effective learning media that can improve learning outcomes and students' interest in physics. The solution proposed is the development of an e-module learning physics on static electricity that can help students understand concepts and improve problem solving and critical thinking skills. This type of research is qualitative descriptive research. Research data collection instruments in the form of a questionnaire analysis of teacher needs, and a questionnaire analysis of student needs. The results of this study are the use of learning media on static electricity material in the four schools is very low. They only rely on textbooks as the only source in the learning process, so that students in the four schools may experience limitations in the exposure of information and learning experiences. Limitations in the use of textbooks can hinder creativity, interactivity, and in-depth understanding in learning, so it is necessary to develop e-modules as learning media for this material.
MOLECULAR DRUG SUSCEPTIBILITY TEST FOR EARLY DIAGNOSIS FOR DRUG RESISTANT TUBERCULOSIS
Authors: Prasad Dr. Rajendra
Published: January 2024

The rise of drug-resistant tuberculosis poses a severe danger to the global effort to eradicate tuberculosis (DR-TB). Delays in the application of drug susceptibility testing (DST) based on culture led to extended durations of treatment failure and persistent tuberculosis transmission. This article's objective is to give a summary of the several rapid molecular drug susceptibility tests that have proven helpful in promptly identifying DR-TB cases, enabling prompt and efficient treatment of those individuals.
TELEMEDICINE AND ITS FUTURE PROSPECTS: A COMPREHENSIVE REVIEW
Authors: Kazim Dr. Ahlam
Published: January 2024

Telemedicine, Recent breakthroughs in communication technology and a global trend toward digitization have spurred an unparalleled surge in the use of technology to provide healthcare services remotely. In primary care, telemedicine typically takes the form of phone discussions between the patient and the doctor regarding non-emergency medical issues that don't need to be seen in person. When in-person consultation is required, telemedicine enhances rather than replaces it. Right now, the true value of telemedicine is in the convenience it provides to both patients and providers by eliminating the need for in-person visits in order to receive medical advice or treatment. Additionally, it is less expensive than waiting to see a physician or other healthcare professional. After a doctor's office closes, telemedicine can assist with choosing critical calls as well. When it comes to monitoring patients with long-term conditions like diabetes, hypertension, or high cholesterol, it is extremely beneficial. The ease of telemedicine can be advantageous for those who don't have an urgent medical issue but still need assistance with lifestyle changes, medication refills, dose adjustments, or even just getting access to support groups. The ability to schedule telemedicine consultations in addition to necessary laboratory tests or vital sign monitoring is a convenient feature. Physicians have actually been using telemedicine for a long time, just not under this label. Although this is true, using broadband internet technology has reduced the cost of audio and video calls and opened them up to a larger segment of the population, making them a viable replacement for the traditional system. This article offers a thorough analysis of telemedicine, including its historical foundations, present uses, difficulties, and potential future developments.
Dlinnaya nekodiruyushchaya RNK NEAT1_1 snizhaet vyzhivaemost' pervichnyh nejronnyh kletok pri EPR-stresse
Authors: Пукаева Н. Е. , Залевская В. Н. , Дейкин А. В. , Таубинская М. И. , Кухарская О. А. , Овчинников Р. К. , Антохин А. И. , Кухарский М. С.
Published: January 2024

Dlinnaya nekodiruyushchaya RNK NEAT1 igraet vazhnuyu rol' v rabote central'noj nervnoj sistemy (CNS) i uchastvuet v razvitii ryada patologicheskih sostoyanij. Povyshenie urovnya NEAT1 v mozge proiskhodit pri nejrodegenerativnyh i psihicheskih zabolevaniyah. Kakuyu rol' igraet takoe povyshenie ostaetsya neyasnym. Funkcional'no NEAT1 svyazyvayut s realizaciej otveta na kletochnyj stress v nervnoj sisteme. Cel'yu raboty bylo ocenit' vliyanie povyshennogo urovnya korotkoj izoformy NEAT1_1 na vyzhivaemost' pervichnyh gippokampal'nyh kul'tur myshej, pri EPR-stresse, inducirovannom s pomoshch'yu ingibitora proteasom MG132. Pervichnye kul'tury byli polucheny ot transgennyh zhivotnyh, ekspressiruyushchih NEAT1_1 cheloveka. Harakteristiku kletochnogo sostava i ocenku apoptoza provodili s pomoshch'yu immunocitohimicheskogo okrashivaniya. Analiz ekspressii genov signal'nyh putej apoptoza osushchestvlyali metodom kolichestvennoj PCR s obratnoj transkripciej. Pervichnye nejronnye kul'tury, poluchennye ot transgennyh zhivotnyh, ne otlichalis' ot kul'tur dikogo tipa po kletochnomu sostavu i morfologicheskim harakteristikam nejronov. Pri indukcii EPR-stressa proiskhodilo usilenie apoptoticheskoj gibeli kletok, v tom chisle nejronov, v kul'turah, ekspressiruyushchih NEAT1_1 v sravnenii s kul'turami dikogo tipa. Aktivaciya genov signal'nyh putej EPR-stressa Atf4 i Ddit3 byla menee vyrazhena v transgennyh kul'turah pri stresse. Krome togo, byl snizhen uroven' ekspressii antiapoptoticheskih genov Bcl2l2 i Mcl1. Takim obrazom, povyshennyj uroven' NEAT1_1 v pervichnyh nejronnyh kul'turah usilivaet apoptoticheskuyu gibel' kletok pri EPR-stresse.
Izmeneniya cirkadiannyh ritmov urovnej citokinov v krovi pacientov s essencial'noj gipertenziej v postkovidnom periode
Authors: Радаева О. А. , Симбирцев А. С. , Костина Ю. А. , Искандярова М. С. , Негоднова Е. В. , Машнина С. В. , Еремеев В. В. , Красноглазова К. А. , Бабушкин И. О.
Published: January 2024

Nesmotrya na bol'shoe chislo issledovanij, posvyashchennyh kolichestvennym harakteristikam citokinovogo profilya pacientov s razlichnymi zabolevaniyami, net tochnyh referensnyh intervalov, i chto ne menee vazhno, ogranicheno chislo issledovanij, analiziruyushchih cirkadiannye ritmy sinteza citokinov u lic s arterial'noj gipertenziej. Cel'yu raboty bylo proanalizirovat' osobennosti cirkadiannyh ritmov soderzhaniya citokinov (IL18, IL18 BP, LIF, sLIFr, M-CSF, MCSFR) v krovi pacientov s essencial'noj arterial'noj gipertenziej II stadii i vydelit' patogeneticheski znachimye osobennosti, sformirovannye posle perenesennoj novoj koronavirusnoj infekcii. Provodili zabor krovi v 7.00–8.00, 12.00–13.00, 19.00–20.00.00, 00.00–1.00 dlya opredeleniya immunofermentnym metodom urovnej IL18, IL18 BP, LIF, sLIFr, M-CSF, MCSFR v techenie trekh sutok u 18 pacientov (56 (95% DI (54–69) let) s essencial'noj arterial'noj gipertenziej (EAG) do i posle perenesennoj novoj koronavirusnoj infekcii. Poluchennye dannye demonstriruyut izmeneniya cirkadiannyh ritmov soderzhaniya citokinov v perifericheskoj krovi u pacientov v zavisimosti ot nalichiya EAG, a takzhe ih dopolnitel'noe iskazhenie v postkovidnom periode, chto v znachimom procente sluchaev imeet stojkij harakter s sohraneniem bolee shesti mesyacev v vide snizheniya soderzhaniya IL18 BP (r < 0,001), dvukratnogo uvelicheniya sLIFr i MCSF (r < 0,001) v 18.00. Opredelena dostovernaya svyaz' mezhdu cirkadiannymi ritmami soderzhaniya sLIFr v krovi i izmeneniya urovnya sistolicheskogo AD s formirovaniem patologicheskogo ritma s rostom AD v nochnoe vremya (Hajt-piker) u lic s EAG v postkovidnom periode. Poluchennye fundamental'nye dannye otkryvayut perspektivy dlya novyh issledovanij immunopatogeneza postkovidnogo perioda u lic s gipertenziej s uchetom cirkadiannyh ritmov soderzhaniya citokinov v krovi.
SEMANGAT REVOLUSI PRANCIS DAN PATRIOTISME NAPOLEON BONAPARTE DALAM PERSPEKTIF BARU SASTRA JAWA
Authors: Rokhim Mukhammad Nur , Nugroho Yusro Edy , Suratno Pardi
Published: January 2024

Peristiwa Revolusi Prancis pada abad XVIII menjadi awal perubahan tatanan dunia guna melepaskan diri dari belenggu perbudakan. Secara politik maupun kultural, semangat revolusi dihidupkan kembali melalui teks sastra. Kanonisasi sastra Jawa kisah Napoleon pada masa kolonial memunculkan perspektif baru pada abad XX, yaitu semangat kebebasan. Hal ini ditemukan dalam teks klasik Cariyos Napoleon Bonaparte koleksi PNRI Nomor NB 1410 yang ditulis pada abad XX. Penelitian ini bertujuan untuk menemukan konsep penafsiran orang Jawa terhadap peristiwa Revolusi Prancis dalam sudut pandang baru sastra Jawa Napoleon. Penelitian ini menggunakan  pendekatan mimetik melalui teori new historicism. Data primer penelitian diambil dari unsur tokoh, penokohan, dan alur, sedangkan data sekunder diperoleh dari karya sastra Jawa lainnya yang berkaitan dengan peristiwa Revolusi Prancis atau bersinggungan dengan Napoleon Bonaparte. Melalui pembacaan hermeneutika, teks ini menawarkan gagasan baru dari konsep budaya yang mengisi teks tersebut, yakni orientasi semangat perjuangan dan nasionalisme rakyat. Tokoh Napoleon Bonaparte dianggap sebagai tokoh yang memberikan keteladanan guna menggugah semangat patriotisme bagi masyarakat Jawa.
An ultrastructural evaluation of the relationship between epithelial rests of Malassez and orthodontic root resorption and repair in man
Authors: Brice Garth L. , Sampson Wayne J. , Sims Milton R.
Published: January 2024

Contrary to previous reports, epithelial cell clusters with ultrastructural features similar to classically defined epithelial rests of Malassez were found, for the first time, in areas of repairing orthodontic root resorption. These observations were made on the buccal root surface of premolars extracted for orthodontic purposes from adolescent patients who had required rapid maxillary expansion. Ultrastructurally, the epithelial clusters ranged in size from 2-8 cells and were characterized by the presence of true desmosomes (macula adherens) and tonofilaments. Certain ultrastructural features of the epithelial cell clusters indicate that' they may be involved in mediating repair cementogenesis subsequent to migration into the resorption bay.
Anterior crown dimensions and relationship in an ethnic Chinese population with normal occlusions
Authors: Lew K K.K. , Keng S. B.
Published: January 2024

Odontometric measurements of anterior tooth crown sizes in a Chinese sample of 85 Class I occlusions were similar to those published in the white population except for larger upper lateral incisors and smaller upper central incisors in Chinese. Sex differences in tooth sizes were seen only in the maxillary and mandibular canines while differences between antimeres were not significant. The Bolton ratios of our Chinese sample revealed a Bolton ratio of 77.89±1.62 for the combined mesio-distal widths of the six mandibular anterior teeth as compared to the combined mesio-distal widths of the six maxillary anterior teeth. Surprisingly, the Bolton ratio in our sample compared favourably with those originally published by Bolton although the interfacial angles, overbite and overjet relationships were statistically different.
The Force Requirements for Tooth Movement Part I: Tipping and Bodily Movement
Authors: Lee Brian W.
Published: January 2024

Specific data on the relation between force and tooth movement is essential not only to facilitate non-traumiatic orthodontic treatment but also to establish a sound basis for appliance design. Whilst the broad approaches to orthodontic tooth movement appear to be the application of tipping and/or bodily movement, no scientific comparison between these two types of movement has yet been made. This article describes experiments which repeat investigations of Storey and Smith into the relation between the force applied 238 and the rate of tipping movement and their extension to include bodily movement. Twenty adolescent male patients requiring distal movement of upper cuspid teeth as a part of orthodontic treatment were each fitted with calibrated cuspid retraction springs. The appliances were designed to induce bodily movement on one side of the mouth concurrently with tipping movement on the other, Initial force applications were identical, and the experiments lasted for up to eleven weeks following one activation of the retraction springs. The results of these experiments were compared with those of other workers, and an explanation of the causes of the past controversy regarding various theories of tooth movement is offered.
RANCANG BANGUN SISTEM PENJADWALAN DAN KONTROL KANDANG KELINCI BERBASIS INTERNET OF THINGS
Authors: Alie Sulthan Mayben Sayyidina , Divayana Yoga , Rahardjo Pratolo
Published: January 2024

These days technology has developed rapidly, almost covering all aspects in humas life for example is automation system. The automation system works without human intervension and complete all works independently. Existing technology can already be connected to each other via the internet network so that it can transmit or receive data automatically. The Internet of Things (IoT) can support automated systems by providing real-time information so that users can monitor the performance of these automated systems. This research was to develop rabbit cage by utilizing microcontroller as monitoring system. The system utilizing Internet of Things (IoT) as monitoring medium between users and devices to help users monitor their rabbit cage remotely. The design installed several sensors such as ultrasonic, temperature, load cell sensors, DS18B20 and water level sensors. This research used Arduino Mega 2560 as main microcontroller and NodeMCU ESP8266 as communication device between the tools and database. The tools use android application on user smartphone that fuctions real time monitoring for the cage. Based on the results of this research by using Arduino Mega as microcontroller board to controlling and monitoring rabbit’s cage has succesfully in monitoring the cage via internet through the NodeMCU ESP8266 intermediary according to the design.
PEMBUATAN PROTOTYPE PLTB TURBIN ANGIN SAVONIUS TIPE-U SUMBU VERTIKAL DENGAN SUDUT KELENGKUNGAN SUDU 135o MENGGUNAKAN SUMBER ANGIN BUANGAN EXHAUST KITCHEN
Authors: Wredhira Wirartama I Wayan Gde , Arta Wijaya I Wayan , Janardana I Gusti Ngurah
Published: January 2024

Bali is known as a tourism island for both local and foreign tourists, therefore there are many hotels, resorts and restaurants for tourists. In order to fulfill the Bali Clean and Green program, the Regional Government of Bali encourages tourism-related businesses, such as hotels, to construct sources of electricity from new renewable energy. The authors use waste energy in the form of exhaust wind from the kitchen exhaust fan in addition to using natural wind energy. Artificial wind is created when waste energy from exhaust fans is converted into a form that can be used to rotate or power a generator. Making a PLTB prototype with a vertical axis Savonius turbine with a blade curvature angle of 135 degrees is the goal of this research in order to increase the wind sweep area and obtain the highest output ratio. This study employed a quantitative methodology. This study was able to maximize the exhaust fan's wind speed, which was 5.84 m/s. The highest generator output value is at 2.93 vdc, 0.62 mmA, and 1.80 Watt for a 2-blade turbine and 40 ohm load, and at 3.22 vdc, 0.74 mmA, and 2.39 Watts for a 4-blade turbine and 40 ohm load.
KAJIAN EKONOMI PEMANFAATAN PLTS ATAP DI GEDUNG RUMAH JABATAN GUBERNUR PROVINSI BALI
Authors: Diva Aristia Gusti Bagus , Dwi Giriantari Ida Ayu , Sukerayasa I Wayan
Published: January 2024

To meet the high demand for electrical energy, an alternative solution that can be applied is the use of New and Renewable EnergyIndonesia targets to achieve Net Zero Emissions (NZE) by 2060. Planning for a rooftop PLTS at the Office of the Governor of the Province of Bali is expected to be able to assist in the expansion of PLTS in the Province of Bali in terms of strengthening Governor Regulations/Regional Regulations that support the use of Solar Power Plants. The design of the rooftop PLTS at the Bali Province Governor's Office Building was carried out using 4 scenarios. Scenario 1 is a design that utilizes the roof area facing the north side. Scenario 2 is by utilizing the roof area only to meet the peak load of the building. Scenario 3 is a design that utilizes the entire roof area of the building that best meets the criteria. Meanwhile, scenario 4 is scenario 2 but uses a microinverter device. The Scenario 2 PLTS design is studied economically because the return on investment is the fastest compared to the other scenario PLTS designs. Based on the economic feasibility analysis of the investment, scenario 2 design has a Net Present Value (NPV) of Rp. 158,771,001, Profitability Index (PI) of 1.32 and a Discounted Payback Period (DPP) of 10.7 years.
O uso das tecnologias em um curso de extensão sobre voleibol: avaliação pelos participantes
Authors: Parente Thomás Augusto , Impolcetto Fernanda Moreto
Published: January 2024

Com o objetivo de avaliar o curso de extensão híbrido “Voleibol, ensino & Pedagogia do Esporte” no que diz respeito a sua estrutura e organização e a relação com as Tecnologias da Informação e Comunicação (TIC), 33 concluintes do curso responderam um questionário com questões fechadas, em escala do tipo-Likert, e dissertativas, caracterizando o estudo como de metodologia mista, sobre quatro tópicos que remetem ao uso das TIC ao longo do processo: a) infraestrutura; b) materiais; c) avaliações; e d) perfil do formador. A maioria dos itens analisados ao longo da escala receberam avaliações positivas e satisfatórias, sendo poucos aqueles com avaliações insatisfatórias, o que pode indicar que o curso de extensão atendeu a proposta prevista. Além disso, entende-se que cursos híbridos, que aliam as TIC com aulas práticas presenciais, são uma alternativa viável para a formação complementar em Educação Física, tanto para graduandos(as) como para profissionais.
The variety of models of terminological units of the hydraulic engineering industry and the sphere of state and municipal procurement
Authors: Galankina Inna Ivanovna , Perfilieva Natalia Vladimirovna , Perfiliev Aleksei Kirillovich
Published: January 2024

The relevance of the study lies in clarifying the terminological status of newly formed units and describing the variety of ways to replenish terminological systems. The subject of the study is the models of terminological units of hydraulic engineering and procurement for state and municipal needs. The aim of the work is to represent the methods of derivation in the language of hydraulic engineering, as well as to identify and classify specific terminological combinations of these industries. The conducted research also made it possible to clarify the criteria for assigning terminological names to the following classes of words: term, quasi-term, pre-term. Practical significance implies the application of the results in the compilation of databases and materials for teaching professional communication in foreign languages. The perspective of the study is a contrastive analysis of these terminological systems in two or more languages in order to clarify the translation of terminological units.  The structural features of the terminological units are determined using contrastive analysis. The selection and comparison of terminological units were carried out on the basis of a solid sample of normative documents from the studied industries. The statistical analysis data demonstrated the frequency of formation of two-, three-, four-, etc. terminological names in hydraulic engineering and in the field of procurement. Practical significance implies the application of the results in the compilation of databases and materials for teaching professional communication in foreign languages. The conducted research allowed us to conclude that the accuracy of expressing the concepts of the new sphere of procurement for state and municipal needs is achieved through verbose models, the components of which are combined by an obligatory valence. The peculiarities of the hydraulic terminological system are the absence of five-, six- and seven-component models, which is largely compensated by the wealth of derivational means and is due to the "age" of this industry. The novelty of the work is determined by several factors: firstly, the terminological status of the quasi-term and pre-term is clarified, and secondly, the criterion of mandatory valence is justified to determine a verbose combination of words as a stable terminological name.
Novel Electric Propulsion System Analysis Method for Electric Vertical Takeoff and Landing Aircraft Conceptual Design
Authors: Lee Donguk , Yee Kwanjung
Published: January 2024

This paper proposes novel enhancements to the electric propulsion system analysis method for electric vertical takeoff and landing (eVTOL) aircraft conceptual design by considering the electrical characteristics of each electrical device in a more accurate manner. To this end, three modules for motor, inverter, and battery analysis are constructed using equivalent circuits and semi-empirical models. First, the motor analysis module is developed using equivalent circuit analysis with the operation control strategy for a permanent-magnet synchronous motor. Second, the inverter analysis module is built using average loss models for the switching and conduction losses. Third, the battery analysis module is improved using the near-linear discharge model to consider the voltage drop during operation. Moreover, additional modules, such as those for calculating the battery stack in series and parallel, as well as regression models for the motor and inverter performance parameters and consideration of the drive system type (direct or indirect, including a reduction gear), are implemented. A comparative study is presented from an analysis and design perspective while changing the drive system type (direct or indirect) and gear ratio, which highlights the importance of modeling electrical characteristics during eVTOL aircraft conceptual design.
Avaliação de habilidades e atitudes no ensino médico com metodologias ativas: estudo bibliométrico
Authors: Mendonça Leonardo Teixeira de , Sefer Celina Claudia Israel , Santos-Lobato Edienny Viana , Mendonça Kamylly Reina Carneiro de , Botelho Nara Macedo , Portella Márcia Bitar
Published: January 2024

Objetivo: Realizar um estudo bibliométrico sobre artigos que avaliaram habilidades e atitudes no ensino médico com metodologias ativas. Métodos: Trata-se de um estudo documental bibliométrico. A busca pelos trabalhos foi realizada nos bancos de dados do PubMed, LILACS e BVS no mês de dezembro de 2022. A análise avaliou o perfil dos estudos, as metodologias de ensino utilizadas, as ferramentas utilizadas para avaliação, o método e os desfechos. Resultados: Obteve-se 150 artigos para análise completa, a maior parte desenvolvida nos Estados Unidos, China e Índia, com mediana de participantes de 107. Os principais desfechos avaliados foram a percepção e aprendizado, sendo a principal ferramenta para essa avaliação o uso de questionários. A principal metodologia de ensino foi o aprendizado baseado em equipes (TBL), a ferramenta mais utilizada foram questionários (criados pelos autores), com validação em apenas 15 estudos. A maioria dos estudos foram transversais e quantitativos. Os termos mais utilizados após análise qualitativa dos corpus textual foram “student”, “medical”, “learn”, “teach”, “study” e “active”. Considerações Finais: a avaliação de habilidades e competência no ensino médico ainda é um campo amplo para pesquisas, dada a não uniformidade da avaliação, devendo ser mais explorada pela comunidade científica, principalmente no Brasil
DeepSPInN - Deep reinforcement learning for molecular Structure Prediction from Infrared and 13C NMR spectra
Authors: Devata Sriram , Sridharan Bhuvanesh , Mehta Sarvesh , Pathak Yashaswi , Laghuvarapu Siddhartha , Varma Girish , Priyakumar Deva
Published: January 2024

Molecular spectroscopy studies the interaction of molecules with electromagnetic radiation, and interpreting the resultant spectra is invaluable for deducing the molecular structures. However, predicting the molecular structure from spectroscopic data is a strenuous task that requires highly specific domain knowledge. DeepSPInN is a deep reinforcement learning method that predicts the molecular structure when given Infrared and 13C Nuclear magnetic resonance spectra by formulating the molecular structure prediction problem as a Markov decision process (MDP) and employs Monte-Carlo tree search to explore and choose the actions in the formulated MDP. On the QM9 dataset, DeepSPInN is able to predict the correct molecular structure for 91.5% of the input spectra in an average time of 77 seconds for molecules with less than 10 heavy atoms. This study is the first of its kind that uses only infrared and 13C nuclear magnetic resonance spectra for molecular structure prediction without referring to any pre-existing spectral databases or molecular fragment knowledge bases, and is a leap forward in automated molecular spectral analysis.
Subcellular targeted anion transporters
Authors: Ryder William G. , Graziotto Marcus E. , Levina Aviva , Hawkins Bryson , Hibbs David E. , New Elizabeth J. , Gale Philip A.
Published: January 2024

Synthetic anion transporters that mediate electroneutral (H+/Cl–) transport have demonstrated anti-cancer activity due to their ability to disrupt subcellular homeostatic environments. Elucidation of the cell death mechanism revealed the transporters’ ability to neutralize lysosomal pH gradients and inhibit autophagy. However, their effect on other subcellular compartments is unknown. Herein, we disclose the first subcellular targeted anionophores that accumulate in various membrane bound organelles to bias their natural propensity to depolarize lysosomes. Confocal microscopy revealed the ability of the naphthalimide-based transporters to localize within their intended membrane-bound organelles. Analogues that contained endoplasmic reticulum (ER) and lysosomal targeting motifs showed an enhanced H+/Cl– transport ability and cytotoxicity compared to non-targeted analogues. Moreover, ER and mitochondrial localization was found to enhance apoptosis in cancerous cells. Our work provides an alternative approach to the design of therapeutically focused synthetic anion transporters and an insight into possible subcellular compartment-specific effects on homeostasis.
Non-Steady State Validation of Kinetic Models for Ethylene Epoxidation over Silver Catalysts
Authors: Brandão Lilliana , Reece Christian
Published: January 2024

Kinetic modelling has been key to developing a mechanistic understanding of the epoxidation of ethylene to ethylene oxide over silver catalysts. However, models of varying active site and mechanistic complexity have all been able to recreate steady state activity and selectivity, leading to an ambiguity about the exact mechanism and nature of the active site. Herein, we validate three leading kinetic models for ethylene epoxidation over metallic silver catalysts by numerically recreating non-steady state Temporal Analysis of Products experiments. We find all of the models are able to very generally recreate the trends observed in the pulse experiments, but that only a two-site model modified to mimic the presence of a subsurface oxygen reservoir is able to accurately recreate the trends observed in a state-altering experiment over oxidised silver. Specific to this model is the inclusion of a nucleophilic oxygen species adsorbed on top of the surface oxide which acts as the active site for the selective oxidation of ethylene. This work exemplifies that while simplified single-site models for ethylene epoxidation are useful tools for broad screening, more complex models are required to capture the precise activity of the catalyst.
Machine learning approaches in predicting allosteric sites
Authors: Nerín-Fonz Francho , Cournia Zoe
Published: January 2024

Allosteric regulation is a fundamental biological mechanism that can control critical cellular processes via allosteric modulator binding to protein distal functional sites. The advantages of allosteric modulators over orthosteric ones have sparked the development of numerous computational approaches, such as the identification of allosteric binding sites, to facilitate allosteric drug discovery. Building on the success of Machine Learning (ML) models for solving complex problems in biology and chemistry, several ML models for predicting allosteric sites have been developed. In this review, we provide an overview of these models and discuss future perspectives powered by the field of Artificial Intelligence such as protein Language Models.
Multigram Synthesis of 4,4-disubstituted-3-oxopyrrolidones – efficient starting material for diverse 3 functionalized pyrrolidones
Authors: Bondarenko Semen , Fedorchenko Anatolii , Novosolov Pavlo , Marchenko Oleksandr , Hanopolskyi Anton , Volovenko Yulian , Volochnyuk Dmytro , Ryabukhin Serhiy
Published: January 2024

The practical rapid development of chemical leads for drug discovery is strongly dependent on scalable procedures for building block synthesis. N-heterocyclic moieties, especially unsaturated ones, remain essential tools in the hands of screening and medicinal chemists. Here, we report four novel chemical block families and the interconversions between them. 4,4-disubstituted-3-oxopyrrolidones synthesis was an essential milestone in the diversity-oriented production of 3-aminopyrrolidones, 3-hydroxypyrrolidones and 3,3’-difluoropyrrolidines. Those can be functionalized with conformationally flexible spirocyclic substituents. We developed the multigram procedure for 4,4-disubstituted-3-oxopyrrolidones from commercially accessible and cost-saving reagents via the short three-step procedure. Also, here we are reporting the robust conversion procedure of 3-oxopyrrolidones to 3-aminopyrrolidones, 3,3’-difluoropyrrolidones and 3-hydroxypyrrolidones, involving a minimal amount of steps. We demonstrate the scope and limitations and further perspectives for such synthetic approaches.