bluuebunny/crossref_metadata_2025 huggingface dataset:
Systematic screening versus clinical gestalt in the diagnosis of pulmonary embolism in COVID-19 patients in the emergency department
Authors: Luu Inge H. Y. , Frijns Tim , Buijs Jacqueline , Krdzalic Jasenko , de Kruif Martijn D. , Mostard Guy J. M. , ten Cate Hugo , Martens Remy J. H. , Mostard Remy L. M. , Leers Math P. G. , van Twist Daan J. L.
Published: March 2023

Background

Diagnosing concomitant pulmonary embolism (PE) in COVID-19 patients remains challenging. As such, PE may be overlooked. We compared the diagnostic yield of systematic PE-screening based on the YEARS-algorithm to PE-screening based on clinical gestalt in emergency department (ED) patients with COVID-19.

Methods

We included all ED patients who were admitted because of COVID-19 between March 2020 and February 2021. Patients already receiving anticoagulant treatment were excluded. Up to April 7, 2020, the decision to perform CT-pulmonary angiography (CTPA) was based on physician’s clinical gestalt (clinical gestalt cohort). From April 7 onwards, systematic PE-screening was performed by CTPA if D-dimer level was ≥1000 ug/L, or ≥500 ug/L in case of ≥1 YEARS-item (systematic screening cohort).

Results

1095 ED patients with COVID-19 were admitted. After applying exclusion criteria, 289 were included in the clinical gestalt and 574 in the systematic screening cohort. The number of PE diagnoses was significantly higher in the systematic screening cohort compared to the clinical gestalt cohort: 8.2% vs. 1.0% (3/289 vs. 47/574; p<0.001), even after adjustment for differences in patient characteristics (adjusted OR 8.45 (95%CI 2.61–27.42, p<0.001) for PE diagnosis). In multivariate analysis, D-dimer (OR 1.09 per 1000 μg/L increase, 95%CI 1.06–1.13, p<0.001) and CRP >100 mg/L (OR 2.78, 95%CI 1.37–5.66, p = 0.005) were independently associated with PE.

Conclusion

In ED patients with COVID-19, the number of PE diagnosis was significantly higher in the cohort that underwent systematic PE screening based on the YEARS-algorithm in comparison with the clinical gestalt cohort, with a number needed to test of 7.1 CTPAs to detect one PE.
Protocol for a study on vicarious resilience in service providers for victims and survivors of violence
Authors: Ferns Alyssa , Roebuck Benjamin S. , McGlinchey Diana , Sattler Patricia L. , Scott Hannah , Killian Kyle D. , Bedard Theresia , Boileau Amy , Tague Connor , Thompson Katherine
Published: March 2023

Few national studies examine victim service providers (VSPs), the important work that they do, and the resources and strategies contributing to their wellness at work. The proposed study aims to investigate the vicarious resilience of those working within the Canadian victim services sector. Participants will be asked about the ways in which they have changed and experienced resilience through exposure to supporting their clients, in addition to the challenges and barriers that still exist. A mixed-methods study incorporating an online survey, virtual focus groups, and semi-structured in-depth interviews will explore job satisfaction, compassion fatigue, turnover intention, instances of workplace microaggressions, vicarious resilience, coping strategies and self-care of VSP participants. The results will contribute to the literature on themes related to the wellness of VSPs. Dissemination of results will provide a Canadian perspective on organizational wellness, including challenges encountered as a result of COVID-19, working conditions that require further advocacy, and emerging perspectives on protective factors.
How is depth of anaesthesia assessed in experimental pigs? A scoping review
Authors: Mirra Alessandro , Gamez Maidanskaia Ekaterina , Carmo Luís Pedro , Levionnois Olivier , Spadavecchia Claudia
Published: March 2023

Background

Despite the large number of pigs involved in translational studies, no gold standard depth of anaesthesia indicators are available. We undertook a scoping review to investigate and summarize the evidence that sustains or contradicts the use of depth of anaesthesia indicators in this species.

Methods

Medline, Embase and CAB abstract were searched up to September 22nd 2022. No limits were set for time, language and study type. Only original articles of in vivo studies using pigs or minipigs undergoing general anaesthesia were included. The depth of anaesthesia indicators reported in the selected papers were divided in two categories: A, indicators purposely investigated as method to assess depth of anaesthesia; B, indicators reported but not investigated as method to assess depth of anaesthesia.

Results

Out of 13792 papers found, 105 were included after the screening process. Category A: 17 depth of anaesthesia indicators were found in 19 papers. Studies were conducted using inhalant anaesthetics as the main anaesthetic agent in the majority of the cases (13/19 = 68.4%), while 3/19 (15.8%) used propofol. The most investigated depth of anaesthesia indicators were bispectral index (8/19 = 42.1%) and spectral edge frequency 95% (5/19 = 26.3%). Contrasting results about the specific usefulness of each depth of anaesthesia indicators were reported. Category B: 23 depth of anaesthesia indicators were found in 92 papers. The most reported depth of anaesthesia indicators were: motor response following a stimulus (37/92 = 40.2%), depth of anaesthesia scores (21/92 = 23.3%), bispectral index (16/92 = 17.8%) and spectral edge frequency 95% (9/92 = 9.8%).

Conclusion

Results highlight the lack of scientifically valid and reliable indicators to ensure adequate depth of anaesthesia in pigs.
“A Ritz Among Laundrettes”: Identities and New Waves in My Beautiful Laundrette
Authors: Fergusson Emma
Published: March 2023

This article analyzes the 1985 Stephen Frears-directed film, My Beautiful Laundrette, as a precursor to the New Queer Cinema movement, and as significant for its portrayal of characters with complex, intersectional identities, living in Thatcher’s England. The laundrette at the film’s center serves as a space in which its characters can find success in business and the freedom to live out their sexuality, but which nonetheless remains inextricable from the oppressive society that surrounds. Furthermore, I investigate the stylistic impact of the film’s origins in television.
Subverting Representation: African Americans in Horror Film
Authors: Gopaul Michael
Published: March 2023

This article explores the slowly changing representation of African Americans in horror films. Scream 2 (1997), I Am Legend (2007), and Get Out (2017) are used as case studies to illustrate what little progression has taken place through the decades in relationship to African Americans on-screen in horror cinema. Topics such as stereotypical tropes, narrative conventions, themes of dehumanization, and racial oppression are investigated across each film to highlight representational similarities and differences through time.
Defying Death and the Natural Order: True Terror in Alfred Hitchcock’s The Birds
Authors: Brackens Andrew
Published: March 2023

This article explores the shame that derives from human mortality and how it is put on display in Alfred Hitchcock’s film The Birds. Using the concepts of the natural order and the animalistic other, this article analyzes the film’s commentary on humanity’s inability to accept death willingly, going out of their way to repress it and disrespect it. Unfortunately for the characters in the film, the birds embody a force of nature that remind the humans with their animalistic gaze that they are not above the laws of nature, sharing the same fate as every living being.
Malignant Pericardial Effusion due to Colorectal Cancer in a Young Man
Authors: Kaur Authors Avleen , Iqbal Sadat , Pittman Meredith E. , Lee Linda
Published: March 2023

A 28-year-old man presented with sudden-onset right lower quadrant abdominal pain and shortness of breath at rest. On examination, he had tachycardia with distant heart sounds and right lower quadrant tenderness. A computed tomography scan showed segmental thickening of the proximal ascending colon and ileum with proximal cecal distension. Echocardiogram confirmed large pericardial effusion with impending tamponade. Video-assisted thoracoscopic surgery was performed for pericardial fluid drainage from a pericardial window. The mediastinal lymph node biopsy revealed metastatic adenocarcinoma cells. A colonoscopy showed a large polypoidal mass in the ascending colon with biopsy confirming poorly differentiated adenocarcinoma, thereby suggesting a possible lymphatic or hematogenous spread without liver or lung involvement.
Diseño, confiabilidad y validez de una escala de autopercepción de éxito para colaboradores de empresas medianas en México
Authors: Robles Acosta Carlos , Hernández Castro Sarahi Guadalupe
Published: March 2023

El estudio de la autopercepción del éxito, como aquella sensación de bienestar personal, laboral, económico o emocional que una persona experimenta a partir del logro de propósitos alcanzados, en actividades que le apasionan, ha sido objeto de estudio en deportistas, gerentes y empresarios, dejando al margen al colaborador; sobre quien realmente depende, en el día a día, el desarrollo de las organizaciones. El propósito de esta investigación fue explorar la confiabilidad y validez de la escala de autopercepción de éxito para colaboradores de organizaciones medianas mexicanas. Se utilizó una escala de inicial de nueve ítems y se aplicó a muestra de 225 trabajadores pertenecientes a seis empresas medianas en México. El análisis de fiabilidad, indicó que la escala cuenta con una consistencia interna adecuada. Los análisis factoriales exploratorio y confirmatorio, permitieron identificar una estructura factorial especificando ítems con cargas estimadas más elevadas. La versión final del instrumento presenta una confiabilidad y validez adecuada para valorar la autopercepción de éxito.
Mapas de atención para destacar pólipos potenciales durante la colonoscopia
Authors: Martínez Carrillo Fabio , Ruiz García Lina Marcela , Guayacan Chaparro Luis Carlos
Published: March 2023

Contexto: Los pólipos son masas protuberantes que crecen a lo largo del tracto intestinal y se consideran los principales precursores del cáncer de colon. En las etapas tempranas, la detección de pólipos representa una probabilidad de supervivencia de hasta el 93%, mientras que, en otras etapas, esta probabilidad disminuye hasta el 8%. A pesar de que la colonoscopia es el método más efectivo para detectar pólipos, varios estudios han demostrado una tasa de pérdida de hasta el 26% en la detección pólipos. Las herramientas computacionales han surgido como una alternativa para soportar la detección y localización de pólipos, pero varios problemas siguen abiertos debido a la alta variabilidad de los mismos.
Método: Este trabajo introduce una estrategia computacional que produce mapas de atención visual con la localización más probable de los pólipos para generar alarmas y apoyar la tarea de detección. Cada fotograma de colonoscopia se descompone en un conjunto de características profundas extraídas de arquitecturas preentrenadas. Dichas características se codifican en una representación densa de Hough para obtener una plantilla del pólipo, que posteriormente se propaga en cada fotograma para obtener los mapas de atención visual. Las regiones máximas son proyectadas a la colonoscopia para dibujar las regiones sospechosas de pólipo.
Resultados:  La estrategia propuesta fue evaluada en los conjuntos de datos ASU-Mayo Clinic y CVC-Video Clinic, reportando una exactitud de 70% de detección entre las cuatro regiones más probables, mientras que con diez regiones se tiene un 80%.
Conclusiones:  Los mapas de atención obtenidos destacan las regiones más probables con pólipos. El enfoque propuesto puede ser útil para apoyar el análisis de la colonoscopia.
La investigación aplicada y el desarrollo experimental en el fortalecimiento de las competencias de la sociedad del siglo XXI
Authors: Castro Maldonado John Jairo , Gómez Macho Leidy Katherine , Camargo Casallas Esperanza
Published: March 2023

Objetivo: Identificar el estado actual del conocimiento de los conceptos relacionados con los procesos de investigación, investigación aplicada, desarrollo tecnológico, desarrollo experimental e innovación, y su relación con la formación, con el fin de obtener o fortalecer competencias pertinentes demandadas por la actual sociedad de la información y el conocimiento. Para ello, se analizan las diferentes definiciones respecto a competencia y su aplicación en los actuales procesos educativos en el entorno de una sociedad globalizada e interconectada. Metodología: Según el planteamiento propuesto por Jackeline Hurtado de Barrera desde la óptica de la investigación holística, la presente investigación se enmarca como un trabajo descriptivo, de tipo documental, transaccional, multivariable, no experimental y de corte cualitativo. Se aplicó la técnica de revisión documental y los instrumentos, matriz de análisis y registro de fuentes. Para el desarrollo de esta investigación se realizó una revisión sistemática mediante la búsqueda en diferentes bases de datos y fuentes de información de carácter científico y académico, en donde se aplicaron palabras claves y conectores booleanos para la adecuada segmentación y recopilación de información durante el periodo 2015-2022. Del mismo modo, en este trabajo se realizaron dos tipos de análisis: uno orientado a la coocurrencia de palabras y el otro de coautoría de los países de filiación de los autores a través del software VOSViewer. Resultados: Se identificó que tanto los conceptos sobre investigación aplicada y desarrollo experimental, como los asociados a competencias tienen diversas características y enfoques de análisis; estos pueden ir desde un punto de vista empresarial pasando por el académico, y hasta el más humanista. Todo redunda en proponer definiciones estructuradas que fortalecen el conocimiento de las interacciones complejas del sujeto con el objeto y cómo, desde esas interacciones, el sujeto puede mejorar su contexto. Conclusiones: Se pudo identificar que el aporte de las actividades de investigación aplicada y desarrollo experimental a través de procesos educativos orientados a la investigación formativa pueden fortalecer las competencias que demanda la actual sociedad la información y el conocimiento, desde diferentes dimensiones; es decir, desde las competencias genéricas conformadas por las básicas y transversales, hasta las específicas enmarcadas por las técnicas, relacionadas concretamente a su área de formación.
„Polska Flota Napowietrzna” (1919–1921) – charakterystyka zawartości oraz formy edytorskiej czasopisma
Authors: Jazdon Grzegorz
Published: March 2023

Mało znanym faktem związanym z powstaniem wielkopolskim jest istnienie trzech czasopism wydawanych przez agendy Wojsk Wielkopolskich. W niniejszym artykule możliwie szeroko została przedstawiona analiza lotniczego pisma „Polska Flota Napowietrzna”, ze szczególnym uwzględnieniem tematyki związanej z jego szatą ilustracyjną i zastosowanymi rozwiązaniami graficznymi. Przed 1919 rokiem cała historia polskiego czasopiśmiennictwa poświęconego aeronautyce obejmuje jedynie warszawskiego „Lotnika i  Automobilistę” (1911–1914). Również lista wielkopolskich pism wojskowych w okresie walk o niepodległość nie jest zbyt rozbudowana, oprócz omawianego periodyku wydawane były jedynie: „Druh” (1918–1919), „Ku Chwale Ojczyzny” (1919–1920) i „Wiedza Techniczna” (1919–1920). „Polska Flota Napowietrzna” była wydawana od sierpnia 1919 do czerwca 1921 roku. Czasopismo było kierowane nie tylko do wojskowych, ale też do wszystkich zainteresowanych tematyką nowoczesności i wynalazczości. W artykule zostaną omówione: częstotliwość wydawania pisma, przemiany tytułu i podtytułu, cena, objętość, lokalizacja redakcji, drukarnie i miejsca dystrybucji. Następnie zostaną przedstawieni najważniejsi autorzy „Polskiej Floty Napowietrznej” oraz struktura i tematyka czasopisma. Całość zamyka analiza aspektów graficznych: papieru, podstawowej makiety pisma, używanych czcionek, okładek periodyku, zdjęć i ilustracji oraz ozdobników i szlaków drukarskich.
Biblioteka a grywalizacja. Rozważania teoretyczne (zarys tematyki)
Authors: Grodź Iwona
Published: March 2023

Niniejszy artykuł zawiera analizę rozważań teoretycznych dotyczących grywalizacji działań w wirtualnej przestrzeni biblioteki. Rewolucją w tym zakresie jest przede wszystkim zmiana formy komunikowania i pozyskiwania informacji, m.in. na temat segmentacji czytelników w przestrzeni wirtualnej biblioteki. Celem tekstu jest wskazanie waloru edukacyjnego synergii różnych nauk: humanistycznych, ekonomicznych i nowych mediów w innowacyjnych podejściach do myślenia o bibliotece XXI wieku. Przykładem takiej synergii jest grywalizacja. Wstępna hipoteza zakłada, że może ona sprzyjać konstruowaniu relacji komunikacyjnych w przestrzeni wirtualnej biblioteki, a tym samym umożliwia dostosowanie oferty do potrzeb nowych pokoleń czytelników. Kluczowa okazuje się wiedza na temat ich segmentacji jako użytkowników kultury online.
Realizacja polityki otwartego dostępu na przykładzie Uniwersytetu Jagiellońskiego w Krakowie
Authors: Szafrański Leszek
Published: March 2023

Celem badań opisanych w artykule było przedstawienie doświadczeń pracowników Biblioteki Jagiellońskiej związanych z wdrażaniem polityki otwartego dostępu na Uniwersytecie Jagiellońskim. Opisane działania skupiają się zarówno na historycznym aspekcie wdrażania polityki, jak i na działaniach kontynuowanych lub podjętych po ogłoszeniu związanych z tym aktów prawnych. Do zbierania danych zostały wykorzystane metody analizy i krytyki piśmiennictwa oraz studium przypadku, których zastosowanie pozwoliło  szczegółowo opisać temat otwartego dostępu do nauki z perspektywy wdrożenia takiej polityki na Uniwersytecie Jagiellońskim. Na kanwie zgromadzonych doświadczeń można stwierdzić, że główne problemy we wdrażaniu otwartej nauki na uczelni to słaba znajomość tematu przez pracowników i brak dostatecznego finansowania. Do głównych zalet natomiast należą: nieograniczony dostęp oraz szersze rozpowszechnienie wyników badań i publikacji naukowych.
Evaluation studies of the new mining projects
Authors: Al-Bakri Ali Y. , Ahmed Hussin A. M. , Ahmed Haitham M. , Hefni Mohammed A.
Published: March 2023

Mining still plays a vital role in providing various sectors with essential materials since many industries depend heavily on mined minerals. Moreover, the mining industry is the primary driver for many economies worldwide. On the other hand, new mining projects face many challenges, the most important of which are risks related to the economic aspects, e.g., the significant uncertainty about mineral resources compared to other engineering projects. Therefore, many jurisdictions worldwide depend on detailed engineering studies conducted according to internationally recognized standards to assess the new mining projects from an economic and technical perspective. In the same context and due to the significant lack of published research in this field, as the literature review revealed, this article reviewed and discussed the different main stages of engineering studies to evaluate new potential mining projects, including scoping, pre-feasibility, and feasibility studies, to ensure that the engineering study report complies with all the recognized main requirements. Results indicated the necessity of adhering to the needs of the engineering tasks while preparing reports of evaluation studies for new mining projects to reduce potential uncertainty risks and thus raise the level of confidence in these types of projects. Furthermore, they showed direct progress between the investigation details conducted in the evaluation studies and the value of the new mining project.
Identifying elevated plasma free triiodothyronine levels: age-adapted reference intervals for pediatrics
Authors: Janot Clément , Perrin Pauline , Bretones Patricia , Plotton Ingrid , Roucher-Boulez Florence , des Portes Vincent , Raverot Véronique
Published: March 2023

Objectives

Elevated free T3 (FT3) is an important feature for the early diagnosis of several diseases among which Grave’s disease or Allan-Hernon-Dudley syndrome. However, there is a lack of age-adapted reference intervals for plasma thyroid hormones in children. We conducted a study to define reference values of peripheral FT3 in children using a commonly used automated immunoassay.

Methods

All thyroid function test (TFT) results from our lab collected during 9 months were extracted anonymously, and reference intervals establishment followed recommendations validated by International Federation of Clinical Chemistry (IFCC).

Results

We defined five reference intervals covering the whole pediatric period. Overall, 26.1% of peripheral FT3 measured in children with normal TSH are out of the adult reference range, and 22.2% are upper it leading to misinterpretation. In a 9-month old patient with severe neurodevelopmental disorders, a pathological elevated FT3 has been securely interpreted using the newly established interval.

Conclusions

The study highlights the poor relevance of adult intervals in pediatric cares, as it confirms that plasmatic FT3 is higher during the whole pediatric period. This work reports useful age-adapted reference intervals for free T3 in pediatrics using a widely used electrochemiluminescent Immunoassay (ECLIA) kit.
A chiral microchip laser using anisotropic grating mirrors for single mode emission
Authors: Li Fangfang , Lapointe Shawn , Courval Théo , Fetisova Marina , Kämpfe Thomas , Verrier Isabelle , Jourlin Yves , Karvinen Petri , Kuittinen Markku , Bisson Jean-François
Published: March 2023

A pair of nanostructured mirrors made of a diffraction grating inscribed in the top layer of a Bragg mirror are designed such that a phase shift near π and different reflected amplitudes exist between transverse electric (TE) and magnetic (TM) reflected polarization states at normal incidence. When a standing wave laser resonator is formed with two such mirrors and the two mirrors’ principal axes are twisted one with respect to the other, this phase shift condition suppresses multiple longitudinal mode emission arising from axial spatial hole burning. In addition, the different amplitudes of TE and TM reflected polarizations create polarization eigenstates with different round-trip losses, suppressing one polarization eigenstate. Laser experiments made with a Yb3+-doped Y3Al5O12 active material reveal enhanced purity of the emission spectrum compared to similar lasers using conventional laser mirrors. The proposed design enables a miniature single mode laser, replacing more complex designs usually needed to achieve that goal.
Crystal structure of E-7-fluoro-2-(2-(trifluoromethyl)benzylidene)-3,4-dihydronaphthalen-1(2H)-one, C18H12F4O
Authors: Zhang Juan , Hou Yun , Zhao Feng-Lan , Meng Qing-Guo
Published: March 2023

C18H12F4O, triclinic, P1̄ (no. 2), a = 7.9400(8) Å, b = 8.1071(9) Å, c = 13.3238(15) Å, α = 

89.394

(
9
)

°

$89.394\left(9\right)^{\circ} $

, β = 

76.343

(
9
)

°

$76.343\left(9\right)^{\circ} $

, γ

 

$$

=

63.411

(
11
)

°

$\text{63.411}\left(11\right)^{\circ} $

, V = 740.79(15) Å3, Z = 2,

R

g
t

${R}_{\mathit{g}\mathit{t}}$

(F) = 0.0472,

w

R

r
e
f

$w{R}_{\mathit{r}\mathit{e}\mathit{f}}$

(F
2) = 0.1244, T = 293 K.
The crystal structure of 4-(4-iodophenyl)-5H-1,2,3-dithiazole-5-thione, C8H4INS3
Authors: Liao Huiyang , Ni Penghui
Published: March 2023

C8H4INS3, monoclinic, P21/c (no. 14), a = 11.8060(19) Å, b = 7.8961(14) Å, c = 11.972(2) Å, β = 

110.981

(
2
)

°

$110.981(2){}^{\circ}$

, V = 1042.1(3) Å3, Z = 4, R

gt
(F) = 0.0279, wR

ref
(F
2) = 0.0739, T = 296(2) K.
Latmos: a semiotic view on the subject’s role in the sustainability of natural and cultural values
Authors: Kalelioğlu Murat
Published: March 2023

Along with the developments in social, scientific, and technological fields, today’s conditions are constantly changing and becoming much more complex. Humans must keep pace with the rapidly changing world, meet requirements, and solve various problems encountered with minimal damage. One of the most crucial obligations is to preserve the delicate balance between nature and culture to make it sustainable for humanity. This study is carried out pursuant to semiotics with an interdisciplinary perspective dealing with the relation of culture with nature and the role of humans, as a subject, in this relation regarding both natural and cultural heritages of Latmos. The study examines the subject’s acts and possible influences on nature, culture, and society in the region. It is seen that there is an uphill battle between two different subjects; the reason for this is a conflict of interest encountered on individual and social planes. On the one hand, one of the subjects is aware of the positive effects of preserving natural and cultural values on society and its future. On the other hand, another subject is unaware of all these or is aware of them but ignores natural and cultural values and destroys them for the sake of self-interest.
National Strength and Conditioning Association Position Statement on Weightlifting for Sports Performance
Authors: Comfort Paul , Haff G. Gregory , Suchomel Timothy J. , Soriano Marcos A. , Pierce Kyle C. , Hornsby W. Guy , Haff Erin E. , Sommerfield Lesley M. , Chavda Shyam , Morris Stephanie J. , Fry Andrew C. , Stone Michael H.
Published: March 2023

Comfort, P, Haff, GG, Suchomel, TJ, Soriano, MA, Pierce, KC, Hornsby, WG, Haff, EE, Sommerfield, LM, Chavda, S, Morris, SJ, Fry, AC, and Stone, MH. National Strength and Conditioning Association position statement on weightlifting for sports performance. J Strength Cond Res 37(6): 1163–1190, 2023—The origins of weightlifting and feats of strength span back to ancient Egypt, China, and Greece, with the introduction of weightlifting into the Olympic Games in 1896. However, it was not until the 1950s that training based on weightlifting was adopted by strength coaches working with team sports and athletics, with weightlifting research in peer-reviewed journals becoming prominent since the 1970s. Over the past few decades, researchers have focused on the use of weightlifting-based training to enhance performance in nonweightlifters because of the biomechanical similarities (e.g., rapid forceful extension of the hips, knees, and ankles) associated with the second pull phase of the clean and snatch, the drive/thrust phase of the jerk and athletic tasks such as jumping and sprinting. The highest force, rate of force development, and power outputs have been reported during such movements, highlighting the potential for such tasks to enhance these key physical qualities in athletes. In addition, the ability to manipulate barbell load across the extensive range of weightlifting exercises and their derivatives permits the strength and conditioning coach the opportunity to emphasize the development of strength-speed and speed-strength, as required for the individual athlete. As such, the results of numerous longitudinal studies and subsequent meta-analyses demonstrate the inclusion of weightlifting exercises into strength and conditioning programs results in greater improvements in force-production characteristics and performance in athletic tasks than general resistance training or plyometric training alone. However, it is essential that such exercises are appropriately programmed adopting a sequential approach across training blocks (including exercise variation, loads, and volumes) to ensure the desired adaptations, whereas strength and conditioning coaches emphasize appropriate technique and skill development of athletes performing such exercises.
Recuperando a fala?
Authors: Eduardo Domingues dos Santos Souza da Silva Luiz
Published: March 2023

Ao longo dos últimos anos, tem crescido consideravelmente o número de pesquisas que, no âmbito da chamada história social do trabalho, têm buscado nos processos da Justiça do Trabalho, uma fonte através da qual se possa ampliar a compreensão das experiências de trabalhadoras e trabalhadores brasileiros na luta por seus direitos, a partir da década de 1930. Se por um lado, esses trabalhos vêm revelando a riqueza desse tipo de fonte, que vai além muitas vezes da própria disputa trabalhista, por outro, têm ajudado a avançar um processo que já conta com algumas décadas, de revisão de certas interpretações da nossa historiografia no que toca à complexa relação entre classe trabalhadora e Estado, especialmente a partir de meados do século XX. Este artigo se propõe, portanto, a apresentar algumas dessas pesquisas e algumas das contribuições que elas têm dado a esse campo de estudos.
O Patrimônio e a Memória da Ditadura Civil-Militar Brasileira
Authors: Vedana Angélica
Published: March 2023

A partir do processo de abertura política no Brasil, na década de setenta, releituras e interpretações acerca da memória da ditadura civil-militar (1964-1985) tiveram início, gerando uma trajetória de disputas acerca do que deveria ser lembrado e do que deveria ser esquecido ou até mesmo silenciado. No âmbito das reparações, projetos de lei, a nível local, regional e nacional, podem contribuir para o alcance de políticas voltadas à ressignificação da memória da ditadura civil-militar. Neste sentido, a pesquisa tem como objetivo perceber a influência do Terceiro Plano Nacional de Direitos Humanos (PNDH-3) na elaboração projetos de lei tramitados na Câmara de Vereadores da cidade de Porto Alegre, nomeadamente no caso da Avenida Castelo Branco, objetivando analisar o caráter dessas proposições e as disputas em torno dessa memória.
Elevated Monocyte to High-density Lipoprotein Ratio Is a Risk Factor for New-onset Atrial Fibrillation after Off-pump Coronary Revascularization
Authors: Mu Yameng , Niu Jiayin , Zhang Min , Liu Pengfei , Hua Cuncun , Guo Yulin , Zhong Guangzhen
Published: March 2023

Atrial fibrillation (AF) is a common complication of coronary revascularization. Currently, the mechanisms of postoperative AF are unclear. This study was aimed at investigating the risk factors for new-onset AF (NOAF) after coronary revascularization and exploring the early warning effects of clinical inflammatory markers. A retrospective analysis was conducted on 293 patients with unstable angina pectoris who underwent coronary artery revascularization in Beijing Chao-Yang Hospital, Capital Medical University, between April 2018 and June 2021, including 224 patients who underwent coronary artery bypass grafting and 69 patients who underwent one-step hybrid coronary revascularization. Baseline data, clinical data, blood indicators and AF episodes within 7 days after the surgery were collected. Participants were divided into two groups according to whether AF occurred, and the data were analyzed between groups. In addition, multivariate logistic regression was used to explore the independent risk factors for developing AF post coronary revascularization. Aging, a larger left atrial inferior-superior diameter, use of an intra-aortic balloon pump, a greater blood volume transfused during perioperative period and a higher monocyte to high-density lipoprotein ratios on postoperative day 1 were independent risk factors for NOAF after coronary artery surgery.
Unraveling Interior and Exterior Circumstances
Authors: Grosland Tanetha
Published: March 2023

The role of emotions in leadership and policy research is often ignored, indicating the need for an investigation of how researchers’ emotions and the interpretation of emotion in research impact the research process itself. Although at times contradictory and controversial, emotion is the one terrain that unites us in personhood; yet how emotions are understood is said to be defined and controlled by politics. Inspired by critical theories, especially those concerning emotion, this essay aims to theoretically interrogate missed emotion cues when conducting emotional research. This investigation grew out of two research stories of antiracist pedagogy that are laden with emotions. Contemporary observations indicate that the experience of researching emotions (un)consciously alters a researcher’s emotions and thus radically impacts how one ultimately researches emotion. This suggests that emotions in leadership research on political subjects have serious and profound impacts on researchers in ways that are often misunderstood. Concluding remarks note the significant role that research guided by critical theory plays in understanding how scholars’ emotions impact their leadership and policy research on political subjects.
The cell cycle and cell size influence the rates of global cellular translation and transcription in fission yeast
Authors: Basier Clovis , Nurse Paul
Published: March 2023

How the production of biomass is controlled as cells increase in size and proceed through the cell cycle events is important for understanding the regulation of global cellular growth. This has been studied for decades but has not yielded consistent results, probably due to perturbations induced by the synchronisation methods used in most previous studies. To avoid this problem, we have developed a system to analyse unperturbed exponentially growing populations of fission yeast cells. We generated thousands of fixed single‐cell measurements of cell size, cell cycle stage and the levels of global cellular translation and transcription. We show that translation scales with size, and additionally, increases at late S‐phase/early G2 and early in mitosis and decreases later in mitosis, suggesting that cell cycle controls are also operative over global cellular translation. Transcription increases with both size and the amount of DNA, suggesting that the level of transcription of a cell may be the result of a dynamic equilibrium between the number of RNA polymerases associating and disassociating from DNA.
Investigation of aluminum alloy 6061 in Wire-EDM regarding surface roughness and material removal rate by adopting optimization techniques
Authors: MOHD SAIF  , Ritik Kumar Rawat
Published: March 2023

Wire-electric discharge machining offers a number of benefits in comparison to traditional manufacturing processes likewise, no obvious mechanical cutting traces also hard and rigid materials can be processed perfectly in WEDM. Since, aluminum alloys are used in aerospace, shipbuilding, breathing gas cylinders for scuba diving, surgical components and automotive industry for their high-strength-to-weight ratio, accurate shapes and dimensions. Through this method, complicated structures made of aluminum alloy are produced in a single setup with incredibly tight tolerances. The present investigation explores WEDM for AA6061 to optimize different process variables for attaining performance measures in terms of maximum MRR and minimum SR. Taguchi’s L18 OA matrix, S/N ratio, ANOVA and Grey Relational Analysis were employed to optimize SR and MRR. It has been noted from ANOVA that pulse on time and peak current are the most influential aspects for MRR and SR with their contributions of 13.33% and 16.25% respectively. Further, the best possible considered parameters setting has been established by applying GRA for MRR and SR are, pulse on time-50µs, pulse off time-13µs and peak current-4 amp.
Newest challenges of the European Union’s energy policy - legal aspects
Authors:   Faculty of Law and Administration, University of Szczecin, Poland, Szwed Agata
Published: March 2023

In the face of the most recent geopolitical events in Europe that have been carrying the burden of the COVID-19 pandemic and the war in Ukraine, there have been significant changes on the European Union’s energy market. The aim of this article is to analyse and assess the practice of managing energy in the European Union from the perspective of EU energy in the context of these crises. It will present legislative changes at the Union level in the energy policy sector that are driven by these events and that force a change in attitudes towards energy management. It will use methods typical to law studies, that is the analysis of the law in force, the analysis of the development of relevant laws in history and legal comparison. Research results and conclusions point out that urgent binding legislative changes on the EU forum are necessary to adjust the energy policy to the existing reality and to face the most recent trials. Further legislative steps will be necessary to become independent from Russian raw materials and, primarily, to adapt the provisions of the European Green Deal and to provide further guidance to eliminate administrative barriers and to protect consumers on the energy market. The final part of the article identifies measures the EU must take in the short-, mid- and long-term perspective.
The Internationalisation of Polish Firms under Covid 19 Conditions – Results of an Exploratory Study
Authors:   Poznań University of Economics and Business, Gorynia Marian , Trąpczyński Piotr ,   Poznań University of Economics and Business
Published: March 2023

Goal – The present paper addresses the research question as to how previous firm internationalisation leads to sustained commitment to further internationalisation under the conditions of the COVID -19 crisis. Research methodology – The study uses descriptive statistics based on a quantitative survey of 120 Polish exporters from manufacturing sectors. Score – The authors have found some evidence which partly contradicts previous expectations that firms with stronger previous involvement in internationalisation are more likely to sustain or increase their internationalisation commitment during the pandemic and in the post pandemic landscape. Originality / value / implications / recommendations – The authors have explored the boundary conditions under which internationalised firms sustain or extend their internationalisation commitment under pandemic conditions.
Verbotonalni model rehabilitacije i odgoja i obrazovanja učenika oštećena sluha i/ili govora s posebnim osvrtom na rad u osnovnoj školi poliklinike SUVAG, Zagreb
Authors: Bakota Koraljka , Pavičić Dokoza Katarina , Bilonić Milošević Silvana
Published: March 2023

Verbotonalna metoda, koja se provodi kao bazična metoda rada u rehabilitacijskim i odgojno-obrazovnim postupcima u Poliklinici SUVAG, temelji se na strukturalističkom pristupu govornoj komunikaciji. Primjenjuje se u radu s osobama oštećena sluha ili osobama s govorno-jezičnim ili pak komunikacijskim poremećajima. Načela verbotonalne metode utkana su u sve rehabilitacijske i metodičke postupke koji se provode u Poliklinici SUVAG, pa tako i u Osnovnoj školi Poliklinike SUVAG, o čijim se posebnim uvjetima školovanja govori u radu. Slušanje je baza govora i jezika, a time i komunikacije. U Službi za medicinsku rehabilitaciju djece školske dobi i u Osnovnoj školi Poliklinike SUVAG logopedi, audiorehabilitatori i verbotonalni stručnjaci provode rehabilitaciju slušanja i govora po verbotobalnoj metodi akademika Petra Guberine. Specifični rehabilitacijski i obrazovni verbotonalni postupci provode se uz uporabu verbotonalnih elektroakustičkih aparata i specijalizirane opreme. U kompleksnoj rehabilitaciji unutar koje je i Osnovna škola, provode se posebni verbotonalni postupci kao što su stimulacije pokretom i glazbene stimulacije (fonetska ritmika). Učenici viših razreda imaju izborne predmete Kulturu govora i Vizualnu i medijsku kulturu kojima se potiče govorno-jezični razvoj i komunikacija. Poštujući načela verbotonalne metode koja podrazumijevaju djecu i učenike kao aktivne sudionike svih procesa vođenih od verbotonalnih stručnjaka raznih profila, osigurava se profesionalnost i uspješnost rehabilitacije i nastave.
Diffuse sclerosing variant papillary thyroid carcinoma has worse survival than classic papillary thyroid carcinoma: a meta-analysis
Authors: Crayton Henry , Wu Katherine , Leong David , Bhimani Nazim , Gild Matti , Glover Anthony
Published: March 2023

Diffuse sclerosing variant (DSV) of papillary thyroid carcinomais a rare form of thyroid cancer that demonstrates more aggressive histopathology than classical papillary thyroid carcinoma (c-PTC); however, if this leads to worse survival is debated. Many DSVs are driven by fusion events which are of recent clinical importance due to the advent of targeted RET inhibitors. A systematic search and meta-analysis of the literature was performed to compare outcomes of disease-specific mortality (DSM), metastatic and recurrent disease and the incidence of fusion events between DSV and c-PTC to July 2022. The Newcastle–Ottawa Quality Assessment studies was used to assess quality. An odds ratio (OR) was utilised to measure outcomes with 95% CIs. The Preferred Reporting Items for Systematic Reviews and Meta-analysis guideline was followed. Seventeen studies were included with 874 DSV patients compared to 76,013 c-PTC patients. DSV patients had worse DSM (OR=2.50, 95% CI 1.39–4.51) and presented with a higher rate of metastatic lymph nodes (OR = 5.85, 95% CI 2.73–12.53) and more distant metastases (OR = 3.83, 95% CI 2.17–6.77). DSV patients had higher odds of recurrent disease (OR = 3.23, 95% CI 2.00–5.23) and overall distant metastasis (OR = 2.70, 95% CI 1.74–4.17). Rates of RET fusion alterations for DSV ranged from 25 to 83%. DSV has a worse prognosis than c-PTC with higher rates of recurrent disease and distant metastasis. The high prevalence of RET fusions offers the potential to improve outcomes for patients with DSV.
Serotonin alters the response to a glucose challenge in lactating cows
Authors: Pszczolkowski Virginia L , Connelly Meghan K , Beard Adam D , Benn Amara D , Laporta Jimena , Hernandez Laura L , Arriola Apelo Sebastian I
Published: March 2023

Energy partitioning in lactating cows affects milk production, feed efficiency, and body reserves, with the latter having health implications for the transition into the following lactation. One molecule likely involved in the regulation of energy partitioning is serotonin. The objective of this experiment was to explore how increasing circulating serotonin, by intravenous infusion of the serotonin precursor 5-hydroxytryptophan (5-HTP), affects metabolic responses to a glucose challenge in midlactation cows as a means to manipulate energy partitioning. We intravenously infused Holstein cows with 5-HTP (1 mg/kg bodyweight dissolved in saline, n = 11) or saline alone as control (n = 9) over 1 h/day for 3 days. Cows were fasted overnight on day 2. On day 3, fasted cows were given an intravenous bolus of glucose (0.092 g/kg bodyweight). Blood samples were collected for the following 120 min for metabolic and hormonal analysis. Infusion of 5-HTP elevated circulating concentrations of serotonin and free fatty acids, reduced the concentration of insulin and amino acids, and did not affect the concentration of glucose and glucagon before the glucose challenge. Surrogate insulin sensitivity indices indicated improved insulin sensitivity in 5-HTP cows, but due to the unique metabolism of lactating ruminants, these index changes may instead reflect effects in insulin-independent glucose disposal, like milk synthesis. Challenging 5-HTP-treated cows with a glucose bolus reduced the insulin spike and blunted the decrease in free fatty acids, compared to saline cows, without changing glucose dynamics. Overall, these results suggest that serotonin stimulates insulin-independent glucose disposal, requiring less insulin to maintain normoglycemia.
Serum anti-Müllerian hormone (AMH) concentration during pregnancy: a longitudinal study
Authors: McCredie Sarah , An Belinda , McShane Monika , Ledger William , Venetis Christos A
Published: March 2023

A prospective longitudinal cohort study aimed to longitudinally examine the kinetics of anti-Müllerian hormone (AMH) during the first two trimesters of pregnancy. Pregnant women with stored first-trimester serum samples were recruited at 24–28 weeks gestation during their gestational diabetes testing, where they provided an additional serum sample. The samples were analysed for AMH, oestradiol and progesterone concentrations. A decrease in serum AMH was observed in 40 out of 45 (88.9%) (95% CI: 75.9–96.3%) of the participants in this study. The median serum AMH concentration was 10.9 pmol/L in the first trimester and 6.5 pmol/L during the second trimester, with a significantly different distribution of the values between the first-trimester and the second-trimester AMH samples (P < 0.001). The median percentage of AMH difference of −39.8%. This study demonstrated a significant decrease in serum AMH levels from the first to the second trimester of pregnancy. The absolute decrease in AMH levels seems to be positively associated with first-trimester AMH levels, whereas the percentage of AMH difference is not. Further studies are required to elucidate the potential physiological mechanisms of this finding.

Lay summary

Anti-Müllerian hormone, also known as AMH, is produced by developing ovarian follicles in the ovary. The concentration of AMH in the serum is used as a marker of ovarian reserve. This marker has been shown to vary throughout the menstrual cycle and in women using hormonal contraception. This study examined this marker in women in the first and second trimesters of pregnancy to determine if it is variable throughout pregnancy. The study found that there was a significant decrease from the first to second trimester, with a larger decrease seen in women who had a higher first-trimester concentration of this marker. Further research is required to determine the physiological mechanism which causes the reduction of AMH in pregnancy.
Impact of some plant source additives on enhancing the properties and antifungal activities of pulp made from linen fibers
Authors: Taha Ayman S. , Elgat Wael A. A. Abo , Salem Mohamed Z. M. , Ali Hayssam M. , Fares Yahia G. E. , Elshikh Mohamed S.
Published: March 2023

The effects of some pulp additives on mechanical, optical, and antifungal (Aspergillus terreus Ate456, A. niger Ani245, and Fusarium culmorum Fcu761) properties of papersheets produced from linen fiber pulp were evaluated. The ground materials (80 mesh) of Pinus rigida wood (PRW), Costus speciosus rhizomes (CSR), and Senegalia catechu rhizomes (SCR) were used as pulp additives at the concentrations of 0, 1, 2, and 4%. Papersheets with PRW at 2 and 4% as pulp additives had significant effects on tensile index with 26.41 and 30.22 N.m/g; burst index with 2.91 and 2.92 kPa.m2/g; and tear index with 2.52 and 2.53 mN.m2/g, respectively. The highest (64.36%) and lowest (62.90%) percent of brightness was observed in paper sheets produced from pulp without additives and CSR at 4%, respectively. Scanning electron microscopy showed that the produced papersheets with plant source additives had different degrees of decaying patterns, except for papersheets with PRW as additive, which showed some inhibition against the fungal growth. In conclusion, the mechanical properties of papersheets were significantly enhanced by the addition of the three pulp additives.
Ionic liquid-assisted fabrication of nanocellulose from cotton linter by high pressure homogenization
Authors: Huang Jian , Hou Shuna , Chen Ruiying
Published: March 2023

Nanocellulose (NC) was prepared from cotton linter using ionic liquid (IL) 1-butyl-3-methylimidazolium hydrogen sulfate ([Bmim]HSO4) as both swelling agent and catalyst followed by high-pressure homogenization. Evidence suggested that the IL played a significant role with respect to hydrolysis of the linter cellulose. The effects of various reaction conditions on the NC preparation were investigated in this study. The successful conversion of the cotton to NC was analyzed, which showed that the prepared NC had a uniform rod-like shape that was 50 nm to 100 nm in diameter and 500 nm to 800 nm in length. The characterization of the NC by X-ray diffraction and thermogravimetric analysis revealed that the crystalline cellulose I structure was retained in the NC and it showed stable thermal properties. The recycled ionic liquid exhibited a slightly decreased cellulose hydrolysis ability. The application of [Bmim]HSO4 as both a catalyst and swelling agent introduced an effective and environmentally friendly method for NC production.