bluuebunny/crossref_metadata_2025 huggingface dataset:
Suprachoroidal triamcinolone versus Posterior subtenon triamcinolone either alone or formulated in the management of diabetic macular edema.
Authors: Tharwat Ehab , Ahmed Riad Elzaher Hassan , Eltantawy Basheer , Ezzeldin Ezzeldin Ramadan , Elgazzar Akram Fekry
Published: August 2022

Purpose to compare Posterior Subtenon Triamcinolone acetonide (PSTA) injection either formulated or alone versus suprachoroidal triamcinolone in the management of diabetic macular edema.Methods This study is a prospective interventional study included 75 patients, divided into three groups, each group 25 patients. Group I received a combination of Triamcinolone Acetonide (TA) (40 mg) and VISCOAT, which a combination of sodium chondroitin sulfate (20 mg) and sodium hyaluronate (15 mg). The injection was done in the posterior subtenon space using NAGATA canula. Group II received TA (40 mg) in the posterior subtenon space. Group III underwent injection of 4 mg/100µl of TA in the supra choroidal space.Results We found a statistically significant difference between the three studied groups as regarding to BCVA and CMT at six months postoperative with highest median BCVA and lowest median CMT was observed in the formulated TA group. Conclusion We concluded that early treatment of DME by formulated TA is better than TA alone, and suprachoroidal TA in the form of increasing the BCVA and decreasing the CMT without any elevation of IOP.Trial registration number NCT05464953Date of registration 17/7/2022 (retrospectively registered)
Efficacy of high intensity home mechanical stretch therapy for treatment of Adhesive Capsulitis: A Retrospective Review
Authors: Stinton Shaun , Beckley Samantha , Salamani Alicia , Dietz Devinne , Branch Thomas
Published: August 2022

Background: Adhesive capsulitis is a common cause of shoulder motion loss that can be difficult to treat. Surgical intervention is often necessary when conservative methods fail. High intensity stretch (HIS) treatment may be able to provide increased motion gains while avoiding the cost and complications of surgery.Objectives: The purpose of this study was to review data from patients who were prescribed a HIS device to recover their shoulder motion to determine the efficacy of the device. The hypotheses were that patients would achieve significant ROM gains and that ROM would increase to a level at which patients would be able to avoid a motion loss surgery and perform activities of daily living.Methods: Clinical notes were reviewed for patients whose progress plateaued after 4 weeks of therapy and were subsequently prescribed the HIS device after failing to meet their treatment goals. ROM data were recorded for external rotation, abduction, forward flexion, and internal rotation. Pre- and post-treatment ROM data were compared using t-tests.Results: Significant ROM gains were seen in all planes of motion (p<0.001). Patients gained an average of 29.9° in external rotation with a last recorded rotation of 59.2°. In abduction, patients gained 40.5° with a last recorded abduction of 123.3°. In forward flexion, patients gained 30.3° with a last recorded flexion of 138.7°. In internal rotation, patients gained 15.2° with a last recorded rotation of 57.6°. These last recorded ranges of motion were sufficient to perform nearly all activities of daily living.Conclusions: The HIS device was effective in treating patients with shoulder motion loss as demonstrated by the significant ROM gains in all planes of motion. The ability for a patient to recover lost motion quickly without surgery is of great value to quality of life and in healthcare cost savings. We believe this high-intensity stretch device should be considered for use by patients who are at risk for a motion loss surgery.
A novel multi-application offloading method formobile intelligent vehicles in a cloud-edge hybridenvironment
Authors: Xu Xifeng , Xia Yunni , Zeng Feng , Li Fan , Xie Hong , Fu Xiaodong , Wang Mengdi
Published: August 2022

With the increasing demand for real-time computing services in the Internet ofVehicles(IoV) and the inability to meet the latency requirements of IoVapplications by using cloud computing, multi-access edge computing(MEC) isconsidered a promising paradigm to address the latency-sensitive andcomputation-intensive requirements for meeting IoV applications. We considerthe dependencies in IoV applications and design a hybrid cloud-edge architectureto ensure adaptability and flexibility. We propose a scheduling algorithm thatoffloads tasks to the eNode or cloud for execution after sorting them by urgency.Experimental results show that our algorithm outperforms existing algorithms interms of average completion time, average waiting time, and in-time completionrate of the application, which can provide a better quality of service(QoS) for IoV.
Cardiac Uptake of Mesenchymal Stem Cell-Derived Extracellular Vesicles after Intramyocardial or Intravenous Injection in Murine Myocardial Infarction
Authors: Xu Cynthia Marie , Sabe Sharif A. , Brinck-Teixeira Rayane , Sabra Mohamed , Sellke Frank W. , Abid M. Ruhul
Published: August 2022

Background: In animal models, human bone marrow mesenchymal stem cell-derived extracellular vesicles (MSC-EV) have beneficial effects in cardiovascular disease (CVD) only when administered via intramyocardial injection. The biodistribution of either intravenous (IV) or intramyocardial injection of MSC-EV in the presence of myocardial injury is unknown. Methods: MSC-EV were isolated and labeled with DiD lipid dye. FVB mice underwent left coronary artery ligation followed by either peri-infarct intramyocardial or IV injection of 3*106 or 2*109 particles of DiD-labeled MSC-EV or a DiD-saline control. The heart, lungs, liver, spleen and kidneys were harvested 2 hours post-injection and were submitted for fluorescent molecular tomography imaging. Results: Myocardial uptake of MSC-EV was only visualized after intramyocardial injection of 2*109 MSC-EV particles (p = 0.01), and was not detected after IV injection of MSC-EV (p > 0.9), compared to controls. There was no significantly detectable MSC-EV uptake in other organs after intramyocardial injection. After IV injection of 2*109 particles of MSC-EV, the liver (p = 0.02) and spleen (p = 0.04) appeared to have MSC-EV uptake. Conclusions: This study confirms the role for intramyocardial injection in maximal and effective delivery of MSC-EV. Our ongoing studies aimed at developing bioengineered MSC-EV for targeted delivery to the heart may render MSC-EV clinically applicable for CVD.
Survival analysis of adult midline-located gliomas: Does the H3K27 alteration in adult midline- located gliomas actually indicate a poor prognosis?
Authors: Jung In-Ho , Yoo Jihwan , Park Hun Ho , Lim Jaejoon , Moon Ju Hyung , Kim Eui Hyun , Kang Seok-Gu , Kim Se Hoon , Chang Jong Hee
Published: August 2022

Purpose
Although pediatric diffuse midline gliomas (DMGs) have been studied extensively, and midline-located gliomas (MGs) with H3K27 alterations in children have been shown to have a poor prognosis, few researchers have assessed adult DMGs. We aimed to identify factors affecting the prognosis of adult MGs. This was the first study to investigate the prognosis of adult DMGs according to histological grade and was the largest study to investigate the survival of adult patients with DMGs.
Methods
We reviewed the charts of adult patients diagnosed with MG after undergoing resection or biopsy at our institution between 2010 and 2020. The Gehan–Breslow–Wilcoxon test was used for univariate survival analysis, and the Cox regression proportional hazard model was used for multivariate survival analysis.
Results
Among the 125 adult MGs identified, 45 (36.0%) showed H3K27 alterations. The survival analysis performed on 125 adult MGs indicated that a low histological grade, Karnofsky performance score (KPS) ≥ 80, and age ≤ 60 years were associated with significantly better survival. After adjusting for age, the difference in survival between the H3K27-alteration and wildtype groups was not significant. In the survival analysis of 45 patients with DMG, low histological grade, KPS ≥ 80, total resection, and concurrent chemoradiation therapy were associated with significantly better survival.
Conclusion
Adult MGs did not show a poor prognosis due to H3K27 alterations, unlike pediatric cases. The prognosis of adult MGs is based on the histological grade, age, KPS, adjuvant treatment, and extent of tumor resection.
Peer victimization, depression, and non-suicidal self-injury among Chinese adolescents: The moderating role of the 5-HTR2A gene rs6313 polymorphism
Authors: Li Meijin , Wang Huahua , Li Jingjing , Deng Yuting , Yu Chengfu
Published: August 2022

Background: Peer victimization is a crucial risk predictor for adolescent non-suicidal self-injury (NSSI). However, adolescent NSSI reactions to peer victimization exhibit large individual differences. This study explored whether depression mediated the association between peer victimization and adolescent NSSI, and whether this mediating path was moderated by the 5-HTR2A gene rs6313 polymorphism. Methods: A total of 667 adolescents (Mage = 12.81 ± 0.48 years) anonymously completed the questionnaires regarding peer victimization, depression, and NSSI. Genomic DNA was extracted from saliva and buccal cells from each participant. Results: The results showed that the positive relation between peer victimization and adolescent NSSI was mediated by depression. The triple interaction between peer victimization, rs6313 single nucleotide polymorphism, and sex on adolescent depression was significant. Moreover, the triple interaction between depression, 5-HTR2A gene rs6313 single nucleotide polymorphism, and sex on NSSI was also significant. In girls, homozygous CC individuals in the high peer victimization group reported significantly higher levels of depression and NSSI than participants in the low peer victimization group; the interaction, however, was not significant in boys and CT/TT genotype girls. Conclusions: These findings promote the etiological understanding of adolescent NSSI, highlighting the mediating and moderating effect of peer victimization on NSSI, and provide evidence supporting the relationship between the serotonin system and adolescent NSSI.
Do Aid for Trade Flows Help Reduce the Shadow Economy in Recipient Countries?
Authors: GNANGNON Sèna Kimm
Published: August 2022

The present analysis has assessed the effect of Aid for Trade (AfT) flows on the shadow economy using an unbalanced panel dataset of 106 countries over the period from 2002 to 2015. Empirical results obtained by means of the two-step system generalized method of moments, show that higher AfT flows are associated with a fall in the size of the shadow economy, with less developed countries experiencing a greater negative effect of AfT flows on the shadow economy than relatively advanced countries among recipient countries of AfT flows. AfT interventions reduce the size of the shadow economy in countries that face high trade costs as well as in those that experience a depreciation of the real exchange rate. Finally, AfT interventions reduce the size of the shadow economy in countries that improve the economic complexity level.JEL Classification: F14; F35; O17.
Over expression of recombinant Staphylokinase and reduction of inclusion bodies using IPTG as inducer in E. coli BL21 DE3
Authors: Muttar Barakat Abdul Razzaq , Panchal Rakesh Kumar R.
Published: August 2022

A previous research and studies have established the significance of describing Staphylokinase as a thrombolytic treatment, particularly in patients with cardiovascular disease, stroke, and other life-threatening disorders. Staphylokinase plays a significant part in the coagulation process through formation plasmin-Staphylokinase complex on the surface of the clot which activates plasminogen is generated by some strains of Staphylococcus aureus. The publication described the use of the E. coli strain BL12DE3 to produce the protein via the pET21a transporter is predicated on the use of a chemical stimulator (IPTG) which plays an important role in regulating protein recombinant by stimulating protein synthesis. Strain BL12DE3 activates T7 polymerase, encoding LacI via the pET21a transporter. It has been demonstrated that the IPTG inducer achieves the maximum level of protein expression in the shortest amount of time. A Staphylokinase was generated as a soluble protein in excess of 45% by SDS-PAGE and subsequently purified by chromatography.
Allee effect driven by predation: A study of Gause type predator-prey model
Authors: Sasmal Sourav Kumar , Pal Saheb , Pal Nikhil , Takeuchi Yasuhiro
Published: August 2022

Reduced population growth at low population density has important implications for conservation, colonization success, and wildlife management. In this context, the Allee effect, i.e., the positive relationship between per capita growth rate and biomass at small population density, is a crucial biological phenomenon since it is directly related to population extinction. The present paper deals with a two-species interacting model with predator-prey relationship, where prey population experiences mate finding Allee effect caused by predator. Here we assume that an individual's searching efficiency decreases linearly with predator density due to predation, and investigate how predation intensity affects predator-prey dynamics. Moreover, we consider the Monod-Haldane type functional response for predator-prey interactions, which shows group defense of prey against the predator. We provide a detailed mathematical analysis, including positivity and boundedness of solutions, all biologically feasible equilibria, and their local and global stabilities. From our detailed mathematical analysis, we can observe that when the system carrying capacity is low, at most one interior equilibrium exists, and system dynamics is simple, compared to the case with high carrying capacity, in which multiple coexistence equilibria may exist. We discuss three co-dimension one bifurcations mathematically, e.g., Hopf-bifurcation, transcritical bifurcation, saddle-node bifurcation. We notice multi-stability in our system, where the system can be bi-stable when there are two-interior equilibria with high carrying capacity. However, a unique attractor exists when there is only a single interior equilibrium, and both populations persist. We perform extensive numerical simulations by varying two parameters simultaneously and explore how system dynamics are complex when carrying capacity is high compared to low carrying capacity. Moreover, in the numerical section, we discuss other important biological phenomena, e.g., the paradox of enrichment, bubbling, etc.
Ventricular entry during surgical resection is associated with intracranial leptomeningeal dissemination in glioblastoma patients
Authors: Battista Francesca , Muscas Giovanni , Dinoi Francesca , Gadda Davide , Puppa Alessandro Della
Published: August 2022

PURPOSE
Glioblastoma (GBM) is associated with a poorer prognosis when leptomeningeal dissemination (LMD) is reported. Recently, the role of both ventricular entry (VE) during surgery and subventricular zone (SVZ) localization of tumors in promoting LMD in GBM patients has been debated. This article investigates the role of leptomeningeal dissemination (LMD) after surgical exeresis of GBM of VE and SVZ location of the tumor.
METHODS
We conducted a retrospective analysis of GBMs operated on at our Institution between March 2018 and December 2020. We collected pre-and post-surgical images, anamnestic information, and surgical reports.
RESULTS
Two hundred cases were collected. The GBM localization was periventricular in 69,5% of cases, and there was a VE during the surgical procedure in 51% of cases. The risk of post-surgical LMD in the case of VE was 16%. The rate of LMD was higher in the case of VE than not-VE (27,4% vs. 4%, p < 0.0001). The rate of LMD in periventricular GBM was 19% (p = 0.1131).
CONCLUSION
According to our data, VE is an independent factor associated with a higher rate of post-surgical LMD, and the periventricular localization is not independently correlated to this negative outcome. Neurosurgeons should avoid VE when possible. The decision should be assessed case by case, and the correct surgical strategy should be founded on balancing the need for maximal EOR and the risks associated with VE.
Presentation of a new wood test specimen to investigate the fracture behavior of orthotropic materials under mixed-mode I/II loading
Authors: Fakoor Mahdi , Khali Zahra
Published: August 2022

In this paper, a new test specimen as "Center Notched Disk Tension (CNDT)" to study mode I and II stress intensity factors (SIF’s) in orthotropic materials is presented. In the field of Fracture Mechanics, mode I and II SIF’s play an important role to describe the stress distribution. In CNDT specimens, for crack along the fibers, mode mixity is created by changing the loading direction. Also, by changing the crack-fibers direction for the desired crack-load, various mode mixity can be created. For desired crack-fiber angle, by changing the loading share, different mode mixities are created. Thus, the crack kink changes the loading shares. In this analysis, a comprehensive study is performed on the influence of crack-fibers orientation and crack-loading direction on SIF’s. For the first time, SIF’s are presented for cracked orthotropic specimens in different crack-fibers and crack-loading directions. SIF’s are estimated using the Finite Element Method (FEM). The presented specimen is standardized using a unite load in different directions. The crack length is assumed to be constant. Analytical relationships are also presented for the crack tip parameters in mode I and II. Pure mode I and II conditions are investigated based on SIF’s. Due to the difficulty of establishing pure mode II conditions, it is possible to establish pure mode II conditions at certain crack-fiber and load-crack angles. In these situations, mode II SIF’s can be extracted. The obtained results are validated using reported results in the literature.
Analysis of object detection models and their sampling features for Time series Forecasting Methods
Authors: Mani Pradeep
Published: August 2022

Sampling Features that detect the object model in a time series method for analyse the forecasting of image model that may be uni-variate or multi-variate for preprocessing a model in time series that it can break forecasting, the data should be predicted with the area should distribute the level in the region. Forecast Prophecy prediction denotes the sequence model indicating the time of an event in a series. When there is an insufficient information in a traditional pattern predictive model in a block of data append with this model to fissure the data in the various level it can be monitored by several features when there is a superfluous model data in the applicable area with the inclination epoch section, continual integrant, remnant constituent, obstruct area to be monitored with the order for data availability in the region. The object detected with the variational factor should identify with an accuracy of 0.25 in the existing system. In Proposed model IoU ≥0.5 and the improvement factors will observed in FLOPs in a different computational layer categorized model 23.5%, 46.7 % and 50.0 % in a respective ratio in this method train the model with better accuracy and high precision rate.
High-resolution crystal structure of a metabolic switch protein in a complex with monomeric c-di-GMP reveals a potential mechanism for c-di-GMP dimerization
Authors: Dubey Badri Nath , Shyp Viktoriya , Fucile Geoffrey , Jenal Urs , Schirmer Tilman
Published: August 2022

Bacterial second messengers c-di-GMP and (p)ppGpp have broad functional repertoires ranging from growth and cell cycle control to the regulation of biofilm formation and virulence. The recent identification of SmbA, an effector protein from Caulobacter crescentus that is jointly targeted by both signaling molecules, has opened up studies on how these global bacterial networks interact. C-di-GMP and (p)ppGpp compete for the same SmbA binding site, with a dimer of the former ligand inducing a conformational change of loop 7 leading to downstream signaling. Here, we report a crystal structure of a partial loop 7 deletion mutant, SmbA∆loop in complex with c-di-GMP determined at 1.4 Å resolution. SmbA∆loop binds monomeric c-di-GMP strengthening the view that loop 7 is required for c-di-GMP dimerization. In the crystal, SmbA∆loop forms a 2-fold symmetric dimer via isologous interactions with the two symmetric halves of c-di-GMP. Structural comparisons of SmbA∆loop with wild-type SmbA in complex with dimeric c-di-GMP or ppGpp support the idea that loop 7 is critical for SmbA function by interacting with downstream partners. These results underscore the flexibility of c-di-GMP in binding to the symmetric interface between protein subunits. It is envisaged that such isologous interactions of c-di-GMP will be observed in hitherto unrecognized targets.
PRSS23 (Serine Protease 23) is required for the progression of gastric cancer
Authors: Wang Mengshan , Li Bing , He David C
Published: August 2022

PRSS23 (Serine Protease 23) is a vital serine protease that is related to various types of cancers. However, the correlation between PRSS23 and gastric cancer remains unclear. In our study, our objective is to identify the key biomarkers and signaling pathways by analyzing the RNA-seq data. The GSE204725 was created by the Illumina HiSeq 4000 (Homo sapiens). The gene enrichment study indicated the cAMP signaling pathway and Calcium signaling pathway are the main biological processes during the knockdown of PRSS23 in gastric cancer. Moreover, we identified several interactive genes including NCAM1, HIST1H2BD, VWF, HIST1H2BL, GATA1, RYR2, CHRD, PDE4B, HIST1H4B, and HIST2H4B. Our study may provide new knowledge on the treatment of gastric cancer.
An analysis of lactate dehydrogenase (LDH) levels in advanced stage IV melanoma of the skin: prognostic capabilities and demographic variability
Authors: Desai Amar D. , Chinta Sree , Yeh Christopher , Shah Vraj P. , Shah Radhika , Paskhover Boris , Schwartz Robert A.
Published: August 2022

Background
Despite its limitations, in part due to decreased specificity in advanced disease, serum lactate dehydrogenase (LDH) is one of few serum factors used in cancer staging.
Objectives
This study quantifies the predictive capabilities of LDH in stage IV melanoma of the skin and explores the validity of suggested demographic discrepancies which may exist in its use.
Methods
The 1975–2017 Surveillance Epidemiology and End Results (SEER) database was queried for stage IV cutaneous melanoma cases. Demographic characteristics were compared between LDH groups using chi-square and t-tests. Subsequent Cox multivariable regression was performed to assess survival differences.
Results
334 cases of stage IV cutaneous melanoma (average age: 63.0 years) with measured serum LDH levels were identified. Of these patients, 150 (44.9%) had normal LDH, 112 (33.5%) had LDH < 1.5x upper limit of normal (ULN), 57 (17.1%) had LDH 1.5-10x ULN, and 15 (4.5%) had LDH > 10x ULN. Lower incomes were associated with higher LDH; individuals with incomes <$50,000 had the greatest proportion of LDH 10x ULN (19.2%; p = 0.0031). LDH > 10x ULN also had the lowest proportion of White patients (p = 0.04). On Cox multivariable survival analysis, increasing LDH levels showed increased risk of death (LDH < 1.5x ULN: HR = 2.05, p = 0.01; LDH 1.5-10x ULN: HR = 1.46, p < 0.001; LDH > 10x ULN: HR = 5.91, p < 0.001).
Conclusion
This study reaffirms the utility of LDH as a significant predictor of mortality with incremental severity, suggesting possible use for mortality projections. We note that Black patients and those with lower incomes may be more likely to have an elevated LDH. Older age groups and presence of ulceration among patients with stage IV melanoma were also associated with a greater risk of mortality.
A In-solution Snapshot of SARS-COV-2 Main Protease Maturation Process and Inhibition
Authors: Noske Gabriela , Song Yun , Fernandes Rafaela , Chalk Rod , Elmassoudi Haitem , Koekemoer Lizbé , Owen C David , Oliva Glaucius , Godoy Andre
Published: August 2022

Mpro is the main protease of SARS-CoV-2. Its dimeric form is responsible for cleavage of the viral polyprotein at 11 sites, including its own N- and C-termini. Mpro self-cleavage is called maturation, and it is crucial for enzyme dimerization and activity. Recently, we combined x-ray crystallography with biochemical characterization to depict key steps of the maturation process. A single mutant C145S version of Mpro linked to nsp4 cleavage sequence was introduced, allowing us to monitor enzyme shifts between oligomeric states in a human timescale. In here, we used C145S Mpro to study the structure and dynamics of N-terminal cleavage in solution. Native mass spectroscopy analysis showed that mixed oligomeric states are composed of cleaved and uncleaved particles, indicating that N-terminal processing is not critical to oligomerization. A 3.5 Å cryo-EM structure provides details of Mpro N-terminal cleavage in solution, and a glimpse in the dynamic of the active sites outside the constrains of crystal environment. We explored how different classes of inhibitors shift the balance between oligomeric states of Mpro. While non-covalent inhibitor MAT-POS-e194df51-1 prevents oligomerization, we discovered that the covalent inhibitor Nirmatrelvir induces the conversion of monomers into dimers, even with intact N-terminal. Our data indicates that the Mpro dimerization is triggered by the induced fit caused by the covalent linkage during substrate processing rather than the N-terminal processing.
Origin of Screen-printed Metal Contact Losses in Crystalline Silicon Solar Cells
Authors: Jeong Myeong Sang , Lee Sang Hee , Choi Sungjin , Min Kwan Hong , Lee Jong Hoon , Kang Min Gu , Jeong Kyung Taek , Kwak Sang Kyu , Song Hee-eun , Lee Tae Kyung , Park Sungeun
Published: August 2022

Crystalline silicon solar cells are considered mainstream products in the photovoltaic market. To further improve their performance, it is important to maintain good contact between metal electrodes and the Si surface because the state of the metal–Si interface affects the saturation current density J0.metal and open-circuit voltage. Moreover, the large saturation current density strongly attributes to the performance degradation of solar cells. Therefore, the interfacial structure formed by the metal electrodes and Si surface must be examined to minimize the J0.metal value. In this study, we investigated the formation mechanism of Ag crystallites on the surface of Si emitter layer in screen-printed Ag paste. Interestingly, J0.metal was minimized by Ag epitaxial growth, which was verified using an atomic-scale approach. Furthermore, the effect of P doping on the Ag–Si interfacial structure reduced J0.metal. Our study can provide new insights into the origin of J0.metal for realizing high-performance solar cells.
Micro-batch and Data Frequency for Stream Processing on Multi-cores
Authors: Garcia Adriano Marques , Griebler Dalvan , Schepke Claudio , Fernandes Luiz Gustavo
Published: August 2022

Latency or throughput are often critical performance metrics in stream processing. Applications' performance can fluctuate depending on the input stream. This unpredictability is tied to variations in data arrival frequency, data size, complexity, and other factors. Researchers are constantly investigating new ways to mitigate the impact of these variations on performance with self-adaptive techniques involving elasticity or micro-batching. However, there is a lack of benchmarks capable of creating test scenarios to further evaluate these techniques. This work extends and improves the SPBench benchmarking framework to support dynamic micro-batching and data stream frequency management. We also propose a set of algorithms that generate the most commonly used frequency patterns for benchmarking stream processing in related work. It allows the creation of a wide variety of test scenarios. To validate our solution, we use SPBench to create custom benchmarks and evaluate the impact of micro-batching and data stream frequency on the performance of Intel TBB and FastFlow. These are two libraries that leverage stream parallelism for multi-core architectures. Our results demonstrated that most test cases benefited from micro-batches, especially high throughput applications with ordering constraints. For different data stream frequency configurations, TBB ensured the lowest latency, while FastFlow assured higher throughput in shorter pipelines.
Gaya Komunikasi Matematis Mahasiswa dalam Menyampaikan Materi Pertidaksamaan Melalui Video Pembelajaran Interaktif
Authors: Sari Fadhila Kartika , Fuady Anies
Published: August 2022

Communication style is a way in which a person conveys messages or information. Pre-service teachers need to have good communication skills. Communication is one of the keys to the effectiveness of a learning process. Mathematical communication is divided into two, namely written communication and oral communication. Interactive learning videos are one of the alternative media used in online learning. This study aims to describe the mathematical communication style of pre-service teachers in conveying the material of Inequalities through interactive learning videos. This study uses a qualitative approach. The purposive sampling technique was chosen as the sampling method. The subjects of this study consisted of three students from the mathematics education study program FKIP UNISMA, each of which represented a different cohort level, namely semesters 2, 4, and 6. The results of the three subjects have a distinctive and different communication style in explaining the material of Absolute-Value Inequalities. Based on data analysis, the first student’s communication style tends to be non-assertive, the second student has a manipulative communication style, and the third student’s communication style tends to be more assertive.
Penerapan Group to Group Exchange (GGE) Blended Learning Berbantuan WhatsApp untuk Meningkatkan Keaktifan dan Hasil Belajar Peserta Didik SMAN 1 Jetis Ponorogo
Authors: Hasanah Ulfa Ni'matil , Susiswo Susiswo , Qohar Abd.
Published: August 2022

The purpose of this research is to improve the condition of the online class, especially the activeness of students during the synchronous and asynchronous learning process. This study is also to determine the increase in student learning outcomes on vektor material. Learning uses the Group to Group Exchange (GGE) model in online classes and blended learning assisted by WhatsApp. This study uses a classroom action research design which consists of two cycles. The research subjects were students of Class X MIPA 1 SMAN 1 Jetis Ponorogo. Data on student activity includes discussion activities (asking or answering questions), presentations, and giving responses. This data was collected through observation sheets. Data about student learning outcomes are obtained through written tests or quizzes after the cycle takes place. Data were analyzed using descriptive statistical methods. The results of the analysis showed an increase in activity and learning outcomes after learning using the GGE steps. GGE consists of (1) material distribution; (2) group distribution; (3) group discussion in the WA group; (4) presentation and group responses in the class WA group; and (5) evaluation. Class action taken in the form of reshuffling group members and face-to-face meetings. Student activity increased, in cycle I when online using WhatsApp, all student activities were recorded on WhatsApp chat only 54%. Group discussions in the WA group were less than optimal and presentations using photo sharing and voice notes were also less than optimal. While in the second cycle when blended learning, group discussions using WhatsApp group and face-to-face while face-to-face presentations, student activity became 88%. The learning outcomes of students whose scores are greater than the KKM increased from 24% in the first cycle to 72% in the second cycle, with the class average increasing from 48.48 to 81.76. The results of this study indicate that using a GGE based on WhatsApp-assisted blended learning can significantly increase student activity and learning outcomes.
Single-crystal UV/Vis optical absorption spectra of almandine-bearing and spessartine garnet: Part II. An analysis of the spin-forbidden bands of Fe2+, Mn2+, and Fe3+
Authors: Taran Michail N. , Geiger Charles A. , Vyshnevskyi Oleksii A. , Rossman George R.
Published: August 2022

The UV/Vis single-crystal absorption spectra of two almandine-bearing and several spessartine garnets were measured and their respective Fe2+ and Mn2+ spin-forbidden electronic transitions analyzed. Spin-forbidden bands of Fe3+ are also considered, because many aluminosilicate garnets contain some Fe3+. The spectra of the almandine-bearing garnets were recorded at room temperature between about 10 000 and 30 000 cm–1. The spectrum of a nearly end-member spessartine (97 mol% Mn32+Al2Si3O12) was measured between about 15 000 cm–1 and 30 000 cm–1 at room temperature and 78 K, the latter for the first time. The 78 K spectrum shows absorption features not observed at room temperature. Five additional spessartine-rich garnets with different Mn2+/(Mn2+ + Fe2+) ratios, and two with unusual chemistries, were recorded up to 26 000 cm–1. The spectra of the two almandine-bearing garnets agree well with published results and show several overlapping Fe2+/3+ bands located between about 14 000 and 25 000 cm–1. The spectra were deconvoluted to gain more insight into the electronic transition behavior. These results, together with an analysis of other measured spectra, reveal several absorption features that were previously unrecognized or misassigned. The spectrum of spessartine shows several Mn2+ bands, and most are clearly spaced from one another. A synthesis of various UV/Vis spectroscopic results is made and assignments for the Fe2+/3+ and Mn2+ bands are attempted. The intensities of the Mn2+ spin-forbidden bands and the ligand → metal charge edge observed in the various spessartine spectra are discussed. Spectra of almandine and spessartine have been interpreted using Tanabe-Sugano diagrams that are constructed for cations in octahedral coordination, point symmetry Oh. However, such analysis does not appear to be fully successful because Fe2+ and Mn2+ in garnet have triangular dodecahedral coordination with point symmetry D2. The interpretation of the spectrum of spessartine is especially problematic. An analysis shows that published model calculations of Fe2+ electronic transition energies in garnet are not in good agreement with each other and are also not in full agreement with experimental spectra. First principles calculations are needed to better understand the spin-forbidden transitions of Fe2+, Fe3+, and Mn2+ in garnet.
Assessing Teachers’ Knowledge in Analysing Errors in Mathematical Word Problems of Ghanaian Primary School Pupils
Authors: Asase Stella Sitsofe Yawa
Published: August 2022

The survey investigated teacher knowledge in analysing pupils’ wrong answer solutions in mathematical problem-solving. A sample of 205 pupils and teachers from 35 Islamic primary schools in the Greater Accra Region of Ghana were surveyed. The teachers were sampled through quota sampling, while the pupils were selected via stratified random sampling. A questionnaire and achievement test were used for the survey. Frequency count, percentage, and chi-square test were used as statistical tools for data analysis. The study found that the majority (71.4%) of the primary school teachers in the Greater Accra Region had difficulty preparing a good marking scheme. Also, more than 60% of the teachers were unable to identify and analyse the errors of pupils as well as communicate feedback on the errors. The study found no statistically significant association between knowledge of error analysis and analysing wrong answer solutions (p>0.05). This study concluded that most primary school teachers in the Greater Accra Region of Ghana do not have enough knowledge in analysing mathematical wrong answer solutions of pupils by using Newman’s model synthesis. It is recommended that mathematics teachers in Ghanaian basic schools should use Newman’s model as a standard method of analysing pupils’ work. For this reason, Ghana Education Service, Ghanaian universities, and colleges of education should include Newman’s model during the training of mathematics teachers.
Impact of Performance-Based Financing (PBF) Program on Utilization and Completeness of Partographs in Jimma
Authors: Dube Polite
Published: August 2022

One of the most important quality thematic areas incentivized in PBF is maternity services which among other aspects include the use and completion of partographs when monitoring women in labor. Use f partographs during labor is a key intervention but it is not widely used due to various factors. Thus, the PBF program in Jimma sought to strengthen its use and completion since Q4 2019. A quasi-experimental design was used to review 7,260 mothers’ records from 2018, 2019 and 2021 from both Buno-Bedele (control) and Jimma (intervention) zones. Impact of the PBF program on partograph utilization and completeness was estimated using difference-in-differences (DiD) models in STATA 15. In 2019, partograph utilization was estimated to be 29.2% (CI: 26.6% - 31.8%) in Jimma and 23.5% (CI: 21.1% - 25.9%) in Buno-Bedele. In 2021, utilization increased to 87.2% (CI: 85.3% - 89.2%) in Jimma and 41.4% (CI: 38.7% - 44.2%) in Buno-Bedele. Out of the labor cases monitored with partographs, the completeness was 60.2% (CI: 58.1% - 62.4%) in Jimma and 51.6% (CI: 49.5% - 53.6%) in Buno-Bedele in 2019. In 2021, the completeness increased to 83.2% (CI: 82.3% - 84.2%) in Jimma and but remained the same in Buno-Bedele, 51.3% (CI: 49.7% - 52.8%). PBF accelerated the rate of improvement for both utilization (DiD: 30.8%, p-value < 0.001) and completion (DiD: 24.9%, p-value < 0.001) of partographs. Incentivizing facilities to improve quality of care coupled with coaching and mentorship of health workers is effective in improving quality of service for pregnant women in labor and delivery.
Collection Development Variables and Use of Library Materials in Academic Libraries in South-South Geo-political Zone of Nigeria
Authors: S Ebaye, A.
Published: August 2022

This study investigated the “relationship between collection development variables and use of library materials in academic libraries, in South-South, Nigeria. To achieve the purpose of this study, three research questions were raised, and three hypotheses were formulated to guide the study”. Literatures related to the variables under study were reviewed; accordingly, the design for this study was ex-post facto design with a total population of 16620 students with a total of 800 as the sample for the study. This was done with the help of stratified and purposive random sampling techniques. The questionnaire titled: Collection Development Variables and Use of Library Materials in Academic Libraries Questionnaire (CDVULMALQ) was the instrument used for data collection. The instrument was validated by two experts in measurement and evaluation. The reliability of the instrument was established through the spilt-half method. A trial test gave reliability estimates of 069 to 086, and the hypotheses were tested at a .05 level of significance using Pearson’s Product Moment Correlation Analysis. The results of the analysis revealed a significant relationship between acquisition, weeding, and preservation of library collection and the use of library materials. Based on the findings, it was recommended, among others, that: Government should pay more attention to funding and acquisition of library materials for academic libraries.
Cancer Screening Technology and Attitude of Women Towards Cervical Cancer
Authors: Iram Ayesha
Published: August 2022

Cervical cancer claims over a quarter of a million lives of women annually worldwide. It is believed to be the second most common cancer among women worldwide. Screening is used to detect precancerous changes or early cancers before signs or symptoms of cancer occur. The first case of cervical cancer was founded in the 1970s by Harald Zur Hausen. It is believed to be the second most common cancer among women worldwide. Females becoming sexually active in early age with multiple partners are on high risk. Virtually all cervical cancers are associated with human papilloma viruses (HPV). This study was conducted to understand the levels of knowledge and attitudes of women towards cervical cancer screening in Al Khan Dubai.It assessed the knowledge and attitudes of women about cervical cancer prevention. 70% of the sexually active women really need to go for cancer screening. It shows that 66% of women in al khan are being affected due to lifestyle and it is affecting women’s decision in relation to cervical cancer screening. To improve cervical cancer screening in al khan area, women should be given more information, motivation, awareness, and sensitization, in order to encourage them to go for a cervical cancer screening. Keywords: Cervix, High risk, HPV, Pre-screening methods, Women.
A Review of Cooking Oils (Coconut and Palm Oil) as Blood Plasma Regulator
Authors: Mohammad Aminuddin
Published: August 2022

Cooking oils are major sources of fatty acids and hence, play a major role in altering one’s cholesterol level. Two major forms of cooking oil are coconut oil and palm oil. Both are produced locally in Guyana. However, there is limited usage of both for cooking purposes since the commercial oils, which are touted to be healthier, are used instead. Only poor communities and probably a few middle-income homes utilize these oils. These oils have a positive effect on blood plasma cholesterol by lowering HDL and LDL based on the review of research carried out by various researchers. Keywords: Blood plasma; Cholesterol; HDL; LDL; Oils; Saturated fatty acids; Unsaturated fatty acids.
Peran Kepala Madrasah dalam Meningkatkan Kinerja Guru di MIN 3 Demak
Authors: Fikri Muhammad Ahsanul , Wahyudi Wahyudi
Published: August 2022

The head of the madrasa is a figure who has a big role in running the wheel of the educational organization. The head of the madrasa in the organization is needed to bring organizations to the established objectives. The increase in teacher performance is a about who determines the success of the school / madrasa institution, because from the teachers of changes in the education sector will be achieved. The teacher's factor really determines the formation of quality students. Therefore the role of the madrasa head is needed in order to help teachers to be more professional. The purpose of this study was to be able to find out: (1) to describe the role of the Madrasah Chief of Improving Teacher's performance in MIN 3 Demak (2) to describe the strategy used by the Madrasah Head in Improving Teacher's performance in MIN 3 Demak (3) to describe the constraints and solution of the head of the madrasa in improving teacher performance in MIN 3 Demak. This study uses a qualitative approach. The techniques used in research are observation, interviews, and documentation. Then the data obtained was analyzed by: data reduction, data presentation, and conclusion withdrawal. The results of this study indicate that: (1) the role of the madrasa head in improving teacher performance in MIN 3 Demak is a) head as an educator, b) as a supervisor, c) as a motivator. (2) The strategy used by the head of the Madrasah in improving teacher performance in MIN 3 Demak is a) Discipline, c) Motivation, c) Provision of Rewards and Punishment, d) Training Activities, e) Evaluation. (3) Constraints and Solutions Head of Madrasah In Improving Teacher's Performance in MIN 3 Demak is a) Lack of Facilities and Infrastructure, b) Mastery of Material, c) There are still several educators who are less disciplined. With solutions to strive to meet the facilities and infrastructure needed, including teachers in training and workshops, giving warning and always reminding the importance of behavior of discipline.
Limited Face-to-face Lectures at a State University During the Pandemic
Authors: Listanto Virgiawan
Published: August 2022

The Directorate General of Higher Education, Research and Technology has issued Circular Letter 4 of 2021 concerning implementing Face-to-face Learning for the Academic Year 2021/2022. Universitas Negeri Semarang (UNNES) has responded by giving Circular Letter Number: B/11898/UN37/KM/2021 concerning hybrid Lectures for Odd Semester 2021/2022 in Universitas Negeri Semarang. Limited face-to-face lectures during the Covid-19 pandemic came up with many challenges and required rigorous preparation. It is because UNNES will not take any actions that put both its employees and students at risk. This study uses a qualitative research approach framework that describes a phenomenon and information related to implementing hybrid learning during the pandemic. UNNES has successfully implemented both preparation and implementation stages according to the guideline. No Covid-19 cases have been found caused by performing mixed class. However, there is still a concern about the absence of temporary isolation rooms for academics and students with Covid-19 symptoms/criteria. This part is compulsory based on the circular letter issued by The Directorate General of Higher Education, Research and Technology. It has not been fulfilled yet in almost every department with a hybrid class.
Strategi Manajemen Pemasaran Sekolah Dalam Peningkatan Kuantitas Peserta Didik
Authors: Al Machturoh Noor Afif , Wiranata Rz. Ricky Satria , Noviandari Hanifah
Published: August 2022

Kompetisi antar lembaga pendidikan semakin ketat sehingga sekolah perlu melakukan manajemen pemasaran sekolah dengan baik yang bertujuan untuk meningkatkan kuantitas peserta didik. Fokus penelitian ini adalah strategi manajemen pemasaran sekolah dalam peningkatan kuantitas peserta didik. Penelitian ini bertujuan untuk mengetahui faktor internal dan faktor eksternal serta pola strategi manajemen pemasaran sekolah. Penelitian ini dilakukan di SDIT Luqman Al Hakim Internasional Yogyakarta. Subjek penelitian ini adalah kepala sekolah, kurikulum, kesiswaan, sarpras, TU, dan wali murid SDIT LHI. Metode penelitian ini adalah kulitatif deskriptif pendekatan studi kasus. Data penelitian diperoleh melalui wawancara, observasi, dokumentasi dan kuesioner. Data dianalisis dengan cara reduksi data, penyajian data, analisis SWOT, dan penarikan kesimpulan. Pengecekan keabsahan data menggunakan model triangulasi. Hasil penelitian menunjukan bahwa dalam melakukan manajemen pemasaran untuk meningkatkan kuantitas peserta didik di SDIT LHI terdapat: (1) Faktor internal berupa kekuatan, (2) Faktor eksternal berupa peluang, dan (3) Pola strategi pemasaran terletak pada kuadran I strategi agresif (strength opportunity).