bluuebunny/crossref_metadata_2025 huggingface dataset:
Adjusted Cutoff Scores Increase Sensitivity of Depression Screening Measures in Adolescents With Type 1 Diabetes
Authors: Marker Arwen M. , Patton Susana R. , Clements Mark A. , Egan Anna E. , McDonough Ryan J.
Published: August 2022

OBJECTIVE

To measure the acceptability and diagnostic accuracy of commonly used depression screening measures to determine ideal cutoff scores that sensitively identify depressive disorders in adolescents with type 1 diabetes (T1D).

RESEARCH DESIGN AND METHODS

One hundred adolescents (12–17 years old) completed a reference standard, semistructured diagnostic interview and both long and short versions of five commonly used depression screening measures in the United States. To assess feasibility and acceptability, we used screener completion time and participant ratings, respectively. We used descriptive statistics, area under the receiver operating characteristic (ROC) curve analyses, and paired-sample area differences under the ROC curve to assess each measure’s diagnostic validity against our reference standard and to determine ideal cutoff scores for this sample.

RESULTS

Adolescents had a mean age of 15.0 ± 1.7 years, time since T1D diagnosis of 6.0 ± 4.1 years, and glycated hemoglobin (HbA1c) of 8.9 ± 1.8%. Sixty percent of adolescents were male, 15% endorsed a current depressive disorder, and 15% endorsed lifetime suicidality. Measures demonstrated low sensitivity (0.33–0.67) to detect current depressive disorders using preexisting cutoff scores. However, adjusted cutoff scores increased sensitivity and reduced false negatives. All depression screening measures demonstrated “good” to “excellent” predictive validity, and the Children’s Depression Inventory-2 Short version demonstrated significantly greater diagnostic accuracy than the Patient Health Questionnare-2 item version for adolescents.

CONCLUSIONS

Clinics should consider using screening measures with the greatest diagnostic accuracy as identified in this study and adjusting measure cutoff scores to increase sensitivity and reduce false negatives.
Continuous Glucose Monitoring–Guided Insulin Administration in Hospitalized Patients With Diabetes: A Randomized Clinical Trial
Authors: Spanakis Elias K. , Urrutia Agustina , Galindo Rodolfo J. , Vellanki Priyathama , Migdal Alexandra L. , Davis Georgia , Fayfman Maya , Idrees Thaer , Pasquel Francisco J. , Coronado Walkiria Zamudio , Albury Bonnie , Moreno Emmenlin , Singh Lakshmi G. , Marcano Isabel , Lizama Sergio , Gothong Chikara , Munir Kashif , Chesney Catalina , Maguire Rebecca , Scott William H. , Perez-Guzman M. Citlalli , Cardona Saumeth , Peng Limin , Umpierrez Guillermo E.
Published: August 2022

OBJECTIVE

The efficacy and safety of continuous glucose monitoring (CGM) in adjusting inpatient insulin therapy have not been evaluated.

RESEARCH DESIGN AND METHODS

This randomized trial included 185 general medicine and surgery patients with type 1 and type 2 diabetes treated with a basal-bolus insulin regimen. All subjects underwent point-of-care (POC) capillary glucose testing before meals and bedtime. Patients in the standard of care (POC group) wore a blinded Dexcom G6 CGM with insulin dose adjusted based on POC results, while in the CGM group, insulin adjustment was based on daily CGM profile. Primary end points were differences in time in range (TIR; 70–180 mg/dL) and hypoglycemia (<70 mg/dL and <54 mg/dL).

RESULTS

There were no significant differences in TIR (54.51% ± 27.72 vs. 48.64% ± 24.25; P = 0.14), mean daily glucose (183.2 ± 40 vs. 186.8 ± 39 mg/dL; P = 0.36), or percent of patients with CGM values <70 mg/dL (36% vs. 39%; P = 0.68) or <54 mg/dL (14 vs. 24%; P = 0.12) between the CGM-guided and POC groups. Among patients with one or more hypoglycemic events, compared with POC, the CGM group experienced a significant reduction in hypoglycemia reoccurrence (1.80 ± 1.54 vs. 2.94 ± 2.76 events/patient; P = 0.03), lower percentage of time below range <70 mg/dL (1.89% ± 3.27 vs. 5.47% ± 8.49; P = 0.02), and lower incidence rate ratio <70 mg/dL (0.53 [95% CI 0.31–0.92]) and <54 mg/dL (0.37 [95% CI 0.17–0.83]).

CONCLUSIONS

The inpatient use of real-time Dexcom G6 CGM is safe and effective in guiding insulin therapy, resulting in a similar improvement in glycemic control and a significant reduction of recurrent hypoglycemic events compared with POC-guided insulin adjustment.
Associations of New-Onset Atrial Fibrillation With Risks of Cardiovascular Disease, Chronic Kidney Disease, and Mortality Among Patients With Type 2 Diabetes
Authors: Geng Tingting , Wang Yi , Lu Qi , Zhang Yan-Bo , Chen Jun-Xiang , Zhou Yan-Feng , Wan Zhenzhen , Guo Kunquan , Yang Kun , Liu Liegang , Liu Gang , Pan An
Published: August 2022

OBJECTIVE

Atrial fibrillation (AF) frequently occurs in patients with type 2 diabetes (T2D); however, the longitudinal associations of new-onset AF with risks of adverse health outcomes in patients with T2D remain unclear. In this study, we aimed to determine the associations of new-onset AF with subsequent risks of atherosclerotic cardiovascular disease (ASCVD), heart failure, chronic kidney disease (CKD), and mortality among patients with T2D.

RESEARCH DESIGN AND METHODS

We included 16,551 adults with T2D, who were free of cardiovascular disease (CVD) and CKD at recruitment from the UK Biobank study. Time-varying Cox regression models were used to assess the associations of incident AF with subsequent risks of incident ASCVD, heart failure, CKD, and mortality.

RESULTS

Among the patients with T2D, 1,394 developed AF and 15,157 remained free of AF during the follow-up. Over median follow-up of 10.7–11.0 years, we documented 2,872 cases of ASCVD, 852 heart failure, and 1,548 CKD and 1,776 total death (409 CVD deaths). Among patients with T2D, those with incident AF had higher risk of ASCVD (hazard ratio [HR] 1.85; 95% CI 1.59–2.16), heart failure (HR 4.40; 95% CI 3.67–5.28), CKD (HR 1.68; 95% CI 1.41–2.01), all-cause mortality (HR 2.91; 95% CI 2.53–3.34), and CVD mortality (HR 3.75; 95% CI 2.93–4.80) compared with those without incident AF.

CONCLUSIONS

Patients with T2D who developed AF had significantly increased risks of developing subsequent adverse cardiovascular events, CKD, and mortality. Our data underscore the importance of strategies of AF prevention to reduce macro- and microvascular complications in patients with T2D.
Initiation of New Glucose-Lowering Therapies May Act to Reduce Physical Activity Levels: Pooled Analysis From Three Randomized Trials
Authors: Yates Thomas , Sargeant Jack A. , King James A. , Henson Joe , Edwardson Charlotte L. , Redman Emma , Gulsin Gaurav S. , Brady Emer M. , Ahmad Ehtasham , Stensel David J. , Webb David R. , McCann Gerry P. , Khunti Kamlesh , Davies Melanie J.
Published: August 2022

OBJECTIVE

Sodium–glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP-1RA) reduce body weight and improve cardiometabolic health, but their effect on physical activity is unknown.

RESEARCH DESIGN AND METHODS

We pooled data (n = 148) from three randomized trials to investigate the effect of empagliflozin (SGLT2i) and liraglutide (GLP-1RA), in comparison with sitagliptin (dipeptidyl peptidase 4 inhibitor) and dietary therapies, on accelerometer-assessed physical activity.

RESULTS

Liraglutide (mean −1,144 steps/day; 95% CI −2,069 to −220), empagliflozin (−1,132 steps/day; −1,739, −524), and sitagliptin (−852 steps/day; −1,625, −78) resulted in reduced total daily physical activity after 6 months (P < 0.01 vs. control). Moderate- to vigorous-intensity physical activity was also reduced. Dietary interventions led to no change or an increase in physical activity.

CONCLUSIONS

The initiation of all glucose-lowering therapies was associated with reduced physical activity, warranting further investigation.
Adjusted Cut-Off Scores Increase Sensitivity of Depression Screening Measures in Adolescents with Type 1 Diabetes
Authors: Marker Arwen M. , Patton Susana R. , Clements Mark A. , Egan Anna E. , McDonough Ryan J.
Published: August 2022

  

Objective: To measure the acceptability and diagnostic accuracy of commonly used depression screening measures to determine ideal cut-off scores that sensitively identify depressive disorders in adolescents with type 1 diabetes (T1D). 

Research Design and Methods: One hundred adolescents (12-17 year-olds) completed a reference standard, semi-structured diagnostic interview and both long and short versions of five commonly used depression screening measures in the United States. To assess feasibility and acceptability, we used screener completion time and participant ratings, respectively. We used descriptive statistics, area under the receiver operating characteristic (ROC) curve analyses and paired-sample area differences under the ROC curve to assess each measure’s diagnostic validity against our reference standard and to determine ideal cut-off scores for this sample. 

Results: Adolescents had a mean age of 15.0±1.7 years, time since T1D diagnosis of 6.0±4.1 years, and glycated hemoglobin (HbA1c) of 8.9±1.8%. Sixty percent of adolescents were male, 15% endorsed a current depressive disorder, and 15% endorsed lifetime suicidality. Measures demonstrated low sensitivity (.33-.67) to detect current depressive disorders using pre-existing cut-off scores. However, adjusted cut-off scores increased sensitivity and reduced false negatives. All depression screening measures demonstrated “good” to “excellent” predictive validity, and the Children’s Depression Inventory-2 Short version (CDI-2 Short) demonstrated significantly greater diagnostic accuracy than the Patient Health Questionnare-2 item version for adolescents (PHQ-2A). 

Conclusions: Clinics should consider using screening measures with the greatest diagnostic accuracy as identified in this study and adjusting measure cut-off scores to increase sensitivity and reduce false negatives.  
As patentes, sua possível “quebra”, e seus efeitos na sociedade
Authors: Malgarini Labrunie Pedro , Labrunie Jacques
Published: August 2022

Neste breve trabalho estudaremos qual o conceito das patentes, bem como a possibilidade de acontecer uma “quebra” de patentes em nosso direito nacional, dada a enorme crise de COVID-19 que se alastrou pelo mundo. Além disso, serão analisadas as possíveis consequências que esse instituto ocasionaria no Brasil e no Mundo.
Responsabilidade Social e Defesa dos Direitos Humanos:
Authors: Kolling Gabrielle Jacobi , De Castro Gabriel
Published: August 2022

Com a crescente busca por lucros maiores, restasse claro que as empresas mitigam direitos trabalhistas de seus funcionários para atingir tal meta assim. A incessante busca por maiores ganhos levou os altos escalões das empresas nacionais e transnacionais a quebrarem normas de direito trabalhista nacionais, e convenções firmadas entre os Estados e as organizações internacionais que regulamentam este tema. Este artigo busca conceituar o tema da empresa, empresário e transnacionais no que tange as normas nacionais e internacionais, através de leis, tratados internacionais e doutrina. Assim feito, se buscará exemplificar tais conceitos através de casos que ocorreram, e ainda ocorrem no Brasil. No sentido da metodologia, se usará o método descritivo-analítico através de análises bibliográficas de tratados internacionais e doutrina referente ao assunto. Assim o presente artigo, busca elucidar algumas questões terminológicas e apresentar o tema para debates futuros.
A personalidade jurídica de Direito Internacional Público da Santa Sé e as relações com o Brasil
Authors: Santana Davi
Published: August 2022

As relações internacionais que envolvem a Santa Sé são imensuráveis ao longo da história e ainda hoje exercem um papel relevante no Direito Internacional. Este trabalho condensa autores que escreveram, esparsamente, sobre o tema, para formar uma linha de raciocínio acerca da diplomacia da Sé Apostólica: a origem, os pontos altos na história, os métodos de resolução de conflitos para evitar o juízo, e, o relacionamento com o Brasil, ao analisar o Acordo que os dois entes firmaram, em 2009.
MODEL PEMBERDAYAAN MASYARAKAT MINANGKABAU DITINJAU DARI ASPEK EKONOMI
Authors: Iswadi Iswadi , Fadri Zainal
Published: August 2022

This study aims to examine the economic empowerment model applied by the Minangkabau community, which is known as a society that holds firmly to values, traditions, culture and religion, besides that Minangkabau people have long been known as Minang merchants who adhere to a communal economic system. The cooperative economic system implemented by the Minangkabau community is able to maintain the economic stability of the Minangkabau community, it is necessary to conduct a study to see the model of economic empowerment of the Minangkabau community. The research method used is library research by collecting data through reference books, published scientific journals and other literature to see the applied economic empowerment model. The data collection method is carried out by collecting study materials, reading, making research notes and reviewing study materials related to the research focus. The findings of this study are that the Minangkabau community's economy is stable and able to withstand economic shocks by applying several models of economic empowerment, namely mutual cooperation, cooperation, wandering and trading.Keywords: Empowerment, Minangkabau, Economic Aspect
IMPLEMENTASI PROGRAM KOTAKU MENYELESAIKAN PERSOALAN LINGKUNGAN KUMUH DI KRICAK YOGYAKARTA
Authors: Widiyanti Imas , Baily Ahmad , Mujadidi Shibghotullah
Published: August 2022

Kotaku is one of the programs launched and implemented by the local government to solve the problem of slum areas in Kricak, Tegalrejo, Yogyakarta. This study aims to determine the effectiveness of the program in overcoming environmental problems in the research location. This study uses a qualitative method with a naturalistic approach. Sources of data using primary and secondary data. Research data collection techniques through interviews, observation, and documentation. The validity of the data used triangulation. This study uses data analysis from the Miles and Huberman Model. Data analysis steps include data collection, data reduction, data presentation, and drawing conclusions. The results of the study indicate that the implementation of the Program Kotaku in the Kricak sub-district, Tegalrejo, Yogyakarta City has been running according to PU Number 40/SE/DC/2016. The implementation stage includes the socialization stage, the planning stage, the implementation stage and the sustainable stage. The impacts obtained from the arrangement of slum areas in the Kricak sub-district, Tegalrejo, Yogyakarta include changes in the physical environment to become more organized, clean and livable; raise public awareness to protect the environment together; and can improve the economy of the kricak community by utilizing public facilities that are well organized.Keywords: Implementation, Kotaku Program, Slum Environment
BATAS KEWAJIBAN ANAK BEKERJA DALAM KAJIAN HUKUM KELUARGA ISLAM
Authors: Hidayat Iman Nur , Hermanto Agus , Nurnazli Nurnazli
Published: August 2022

Children are the responsibility of parents, as long as they are not mature (adult) as their needs are the responsibility of parents, but when they grow up there are limits in both normative and positive laws that allow children to work, in reality many children are already working looking for income under the specified age. The problem is when can children work in both normative and positive law? This research is to be able to clearly describe a rule that applies, so that parents do not employ underage children. This research is a library research, namely a literature review of the views of the scholars and the laws and regulations in Indonesia with a philosophical-sociological approach. From a normative legal perspective, scholars agree that a child who has reached puberty can only carry out his religious obligations, including work, because he is considered an adult, while in Indonesian legislation, a child is said to be an adult when he is 21 years old, so that at that age, the child has an established mind, physically and psychologically.Keywords: Minimum Limits, Child, Family Law
MENINGKATKAN MOTIVASI MENGHAFAL AL-QUR’AN SANTRI MADRASAH AL-HIDAYAH DAN AKSI PEDULI LANSIA PASIR SALAM
Authors: Ayudia Dinne Rahma , Sastriana Reva , Amrullah Fahmi , Wandansari Sarah Adilah , Supala Supala
Published: August 2022

The target of this community service is the Pasir Salam area located in Ancol Village, Regol Subdistrict, Bandung City. When the Covid-19 pandemic hit the world, it greatly impacted the elderly people who were poorly met with basic needs and also their health. In addition, the low motivation to memorize the Qur’an among santri to accommodate the need for religious support. This community service aims to help elderly people who are less fulfilled basic needs and health. Then re-cultivate the motivation of learning in memorizing the Qur’an among santri to accommodate the needs of religious support in the Pasir Salam area. Methods used through the process of observation, interview, and practice directly from the results of the implementation of several main programs and support programs. The results of the main program activities and supporting programs show the success rate with the action of caring for the elderly through donations from the local community to help the basic needs and health of the RW 09 Elderly (Pasir Salam), the implementation of fun learning methods that are in harmony with the conditions of the santri in pasir salam area, and the existence of other activities that trigger community sensitivity to social and religious activities in Pasir Salam. It is determined to have gone well, although some of them have been constrained, but can still be implemented. Therefore, in order to maintain the continuity of the entire program after devotion required the participation of all elements.Keywords: Motivation, Memorizing al-Qur’an, Elderly Care
THE PRACTICE OF PAGANG GADAI OF HIGH HERITAGE ASSETS IN KANAGARIAN GANGGO MUDIAK IN THE PERSPECTIVE OF ISLAMIC LAW
Authors: Al Ikhlas Al Ikhlas , Murniyetti Murniyetti , Engkizar Engkizar
Published: August 2022

This study aims to analyze how the practice of pagang gadai is carried out by the community according to the perspective of Islamic law. This study uses a qualitative method with a phenomenological approach, data sources are taken through interviews with ten people in Kenagarian Ganggo Mudiak, Pasaman Regency, West Sumatra Province. To strengthen the interview data, the researcher also made direct observations on the process and procedures for the practice pagang gadai is carried out by the community at the research location. All research data were then analyzed using the Miles Huberman technique. The research findings found two community mistakes in the practice of pagang gadai, namely i) pagang gadai is carried out by the community in Kanagarian Ganggo Mudiak is not in accordance with gadai in the perspective of Islamic sharia law, ii) the practice of pagang gadai is carried out by the community contains elements of usury which is legally contrary to sharia. Islam. Whereas in the Islamic context the application of gadai is not for profit but aims to help others. The recommendation from the research findings is that it is necessary to provide education to the public about how to pagang gadai procedures that are in accordance with Islamic sharia guidelines so that the error in practices is pagang gadai is not sustainable in the community
Strategi Pembelajaran Sekolah Indonesia Kuala Lumpur (SIKL) di Era New Normal
Authors: Partono Partono , Fitriyani Uun , Alawiyah Robbiatul , Maghfiroh Alfi Izza , Darojah Innarotut
Published: August 2022

Penelitian ini memaparkan tentang strategi pembelajaran SIKL yang di hadirkan dampak adanya  pandemi  Covid-19.  Proses pengumpulan data dalam penelitian ini menggunakan metode kualitatif untuk mengetahui proses dan stategi pembelajaran di SIKL. Hasil dari penelitian menunjukkan terdapat pembagian kategori siswa   seperti “high risk” dan “low risk, lalu penggunaan aplikasi  RPP digital yang lebih fokus dan berorientasi pada kompetensi peserta didik, selain itu menerapkan protokol kesehatan yang mengharuskan para guru dan staf kebersihan sekolah menyiapkan sekolah agar sesuai dengan aturan New Normal seperti wajib memakai masker, melakukan cek suhu badan, menata ruang, social distancing, dan pengaturan satu kelas hanya dapat menampung 15 siswa. Kelas juga dilengkapi dengan handsanitizer. Sebagai sekolah yang berintegritas, SIKL memiliki beberapa strategi inovasi dan treatment yang harapannya bisa memberi pengaruh positif kepada siswa yakni meliputi fokus metode mengajar, kurikulum, relasi antar guru dan siswa, dan disiplin sekolah.
COPE Flowcharts and infographics – Changes in authorship. Removal of author – before publication
Authors: Editorial Article
Published: August 2022

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COPE Flowcharts and infographics – How to spot authorship problems
Authors: Editorial Article
Published: August 2022

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An Assessment of Environmental Risk of Bt-Maize on Rove Beetle Communities
Authors: Twardowski Jacek Piotr , Gruss Iwona , Bereś Paweł , Hurej Michał , Klukowski Zdzisław
Published: August 2022

An environmental risk assessment related to the genetically modified crops still needs to be studied. In the non-target organisms, rove beetles seem to be well-chosen arthropods for this purpose. Rove beetle abundance and species diversity were studied in the first large-scale Bt-maize experiment in the south part of Poland for over two years to determine the impact of Bt-maize in comparison to conventional varieties. A genetically engineered Bt-maize variety (DKC 3421 Yield Gard®, event MON 810) and its near-isogenic DKC 3420 were cultivated at two locations. Additionally, two non-Bt varieties sprayed with a lambda-cyhalothrin insecticide were also included for comparative analysis. The results show no significant effects on rove beetle abundance and diversity patterns of the Bt-maize and the nearby isolines. In one locality the mean number of individuals and Simpson dominance was even higher in Bt-maize compared to one reference variety. The Canonical Correspondence Analysis showed rather variety-dependent effects of the rove beetle community. To conclude, considering the abundance and diversity of studied insects, there is no environmental risk arising from Bt-maize cultivation.
The Effect of Communicative Language Teaching (CLT) Method on Speaking Ability and Speaking Anxiety
Authors: Andi Sutanto  , Hasbi Sjamsir  , Susilo
Published: August 2022

This research aims to know the effect of Communicative Language Teaching (CLT) method on speaking ability and speaking anxiety of police brigadier students at police state school of East Kalimantan Regional Police. The research has been conducted through true experimental research design. The result of this research revealed that Communicative Language Teaching (CLT) method affected speaking ability and speaking anxiety of the students at Police State School of East Kalimantan Regional Police in academic year 2021/2022. The alternative hypothesis (Ha) of this study was accepted because the result of analysis used MANOVA showed the p value of speaking ability was less than 0,05 which is 0.000 and for the value speaking anxiety was 0.000 < 0,05. It can be concluded that the CLT method gave the significant effect on the students, speaking ability and the CLT method also reduced students’ speaking anxiety.
Lia Eden Community and the New Religious Movement: Analysis of Social Psychology and Rational Choice Theory
Authors: Takdir Mohammad , Khair Nuzulul
Published: August 2022

This study aims to explain the emergence of the Lia Eden community as a new religious movement in Indonesia. This study also revealed the motivation of people to join the Lia Eden community, which was mostly attended by urban and educated people. This study used qualitative methods to answer the psychological symptoms of the emergence of the Lia Eden community. This study uses a case study on one of the contemporary religious movements in Indonesia, namely the Lia Eden movement. This type of study is in the form of literature or library research by tracing various studies in the form of books, journals, and research reports that are directly related to the emergence of Lia Eden and people’s interest in this movement. The approach used in this research is social psychology and the rational choice theory. This research shows that the emergence of the Lia Eden community is due to the disappointment of the organized religion existence which is considered unable to overcome the modern humanity crisis. From the disappointment was culminated in the organized religion existence, the Lia Eden community influenced everyone to follow this community. They want to achieve peace, harmony, and to treat the spiritual crisis that plagued their lives
Between the Job Creation Act and Labor Act: What’s Specific Time Employee Agreement (PKWT)?
Authors: Gunadi Ariawan , Johan Suwinto , Sudiro Amad
Published: August 2022

President Jokowi signed the Law of the Republic of Indonesia No. 11 of 2020 on Job Creation (UU Cipta Kerja), but the Constitutional Court (MK) decided to conduct a judicial review. According to the Constitutional Court, the government must revise the Job Creation Law within two years. Two of the five petitioners for judicial review express concern about the Job Creation Law's inclusion of Specific Time Employee Agreements (PKWT). A Specific Time Employee Agreement is a contract between a business/employer and its employees for a specified period. The purpose of this study is to examine Specific Time Employee Agreements. This study employs a normative judicial methodology. The research is unique in discussing Specific Time Employee Agreements from two perspectives: the worker and the employer. Additionally, this research examines how Specific Time Employee Agreements have been implemented in practice thus far. The research concludes that workers lack understanding of Specific Time Employee Agreements, raising concerns about the Job Creation Law. The absence of a formulation regarding precarious work creates legal uncertainty for workers. Ineffective communication between the employer and employees has raised suspicions regarding the Specific Time Employee Agreement between the two parties. The Job Creation Law's socialization of labor cluster legislation requires improvement. To avoid misinterpretation, the definition of non-permanent work must be clarified
Is This Part Substantial or Is It Time to Rethink the Concept of Originality in Music?
Authors: Karina Salsalina Itha
Published: August 2022

The vagueness in the concept of originality in music has been problematic, especially relating to the enforcement of copyright. There is no definite line between ideas and the expression of an idea, which is essentially the object of copyright in music. The act of using a general concept in music could be mistaken as substantial taking and even futher a copyright infringement. The purpose of this article is to give a new perspective on the concept of originality in music, specifically in determining the act of substantial taking, and to explain why it could be time to finally rethink this concept. The research shows that the concept of substantial taking, as regulated by is Copyright Act, could hardly be applied to music due to the vagueness in the concept of originality. This reflects the necessity of a standardization for originality in music, which could be achieved through dialogues between musicologists, musicians, and other relevant professionals.
Relação da Terapia de Reposição Hormonal com a incidência e mortalidade no Câncer de Mama: uma revisão integrativa
Authors: Weber Julia Balthazar , Paula Clarice Alves Pimentel de , Paula Evelyne Alves Pimentel de , Vieira Gabriela Diana , Nunes Joseane Elizabete , Terra Letícia Carvalho Dornelas , Santos Mariana Gouveia Lins dos , Murta Rebeca de Andrade Temer , Alves Adrissa Alana Carneiro , Fontenelle Victor Talles de Melo
Published: August 2022

Objetivo: Relatar sobre estudos da terapia hormonal em relação a incidência de mortalidade ao câncer de mama. Métodos: Trata-se de uma revisão integrativa, onde foi realizada uma busca na base de dados PubMed. Diante da pesquisa foram encontrados 97 artigos e selecionados 14 artigos completos. Foram inseridos artigos que abordavam a relação entre câncer de mama e Terapia de Reposição Hormonal. Resultados: Estudos com o uso da terapia de reposição hormonal buscaram encontrar associação e o desenvolvimento do câncer de mama. Apresentaram que a terapia hormonal pode ser usada em longo prazo na prevenção de câncer de mama sensível a progesterona e estrogênio, podendo reduzir o risco da doença. Considerações finais: Pode se evidenciar fatores como: tempo de uso, tipo de terapia utilizada e a densidade mamográfica são variáveis que precisam ser consideradas. Deste modo, se faz necessário novos estudos que aprimorem para melhor compreender a relação da terapia hormonal com a incidência e mortalidade do câncer de mama.
As complicações pós-operatórias em pacientes submetidos a rinoplastia: uma revisão de literatura
Authors: Felippe Rodrigo Maia Santos , Ribeiro Letícia Campitelle Perri , Baptista Vanessa da Silva , Nogueira Guilherme Marques , Toledo Samuel de Oliveira , Reis Bruno Cezario Costa
Published: August 2022

Objetivo: Revisar na literatura o padrão de complicações que os pacientes submetidos à rinoplastia apresentaram após suas operações, especificamente em relação ao tipo etiológico do paciente e à indicação cirúrgica. Métodos: Utilizando o operador booleano “and”, os termos “Rhinoplasty”, “Postoperative Complications” e “Surgery, Plastic” foram utilizados para a busca dos artigos na National Library of Medicine, Biblioteca Virtual em Saúde e Directory of Open Access Journals. Os critérios de inclusão foram ensaios clínicos, randomizados, não randomizados, estudos de caso-controle, estudo de coorte, livre acesso, publicados em inglês, português, espanhol e no intervalo de 2017 a 2022. Resultados: Os nove artigos selecionados, foram avaliadas as complicações pós-operatório de rinoplastia, e foi construído um quadro comparativo, na qual é composta pela indicação cirúrgica, número de indivíduos abordados nos estudos, ano de publicação e idade dos indivíduos avaliados conforme apresentado. Considerações finais: Desta forma, percebeu-se que o edema é descrito como a principal complicação após a cirurgia de rinoplastia. Além disso, a indicação mais óbvia de que ocorrem é baseada na faixa etária de 20 a 65 anos, que é a mais comum.
O clampeamento imediato ou tardio na redução da mortalidade perinatal: uma revisão de literatura
Authors: Baptista Vanessa da Silva , Ribeiro Letícia Campitelle Perri , Felippe Rodrigo Maia Santos , Oliveira Carla Resende Vaz , Reis Bruno Cezario Costa
Published: August 2022

Objetivo: Examinar os potenciais efeitos do clampeamento tardio ou imediato do cordão umbilical na mortalidade de recém-nascidos em relação à idade e características gestacionais. Métodos: Foi realizado uma pesquisa bibliográfica de abordagem qualitativa e caráter descritivo por meio de uma revisão integrativa da literatura nas bases de dados National Library of Medicine, Biblioteca Virtual em Saúde e Directory of Open Access Journals com os descritores:  “Umbilical Cord Clamping” e “Neonatal Mortality”. Os critérios de inclusão foram ensaios clínicos, randomizados, não randomizados, estudos de caso-controle, estudo de coorte, livre acesso, publicados em inglês, português, espanhol e no intervalo de 2017 a 2022. Resultados: Os  13 artigos selecionados, foram avaliados  e foi construído um quadro comparativo, na qual é composta pelo número de indivíduos abordados nos estudos, ano de publicação, avaliado se o  clampeamento tardio ou imediato de acordo com o desfecho e idade gestacional. Considerações finais: Dessa forma, viu-se que, apesar de não reduzir a mortalidade infantil, isso é benéfico na redução da necessidade de hemotransfusões na faixa gestacional de 23 a 37 semanas.
Robotics in neurosurgery: Current prevalence and future directions
Authors: Singh Rohin , Wang Kendra , Qureshi Muhammad Bilal , Rangel India C. , Brown Nolan J. , Shahrestani Shane , Gottfried Oren N. , Patel Naresh P. , Bydon Mohamad
Published: August 2022

Background:

The first instance of a robotic-assisted surgery occurred in neurosurgery; however, it is now more common in other fields such as urology and gynecology. This study aims to characterize the prevalence of robotic surgery among current neurosurgery programs as well as identify trends in clinical trials pertaining to robotic neurosurgery.

Methods:

Each institution’s website was analyzed for the mention of a robotic neurosurgery program and procedures. The future potential of robotics in neurosurgery was assessed by searching for current clinical trials pertaining to neurosurgical robotic surgery.

Results:

Of the top 100 programs, 30 offer robotic cranial and 40 offer robotic spinal surgery. No significant differences were observed with robotic surgical offerings between geographic regions in the US. Larger programs (faculty size 16 or over) had 20 of the 30 robotic cranial programs (66.6%), whereas 21 of the 40 robotic spinal programs (52.5%) were at larger programs. An initial search of clinical trials revealed 223 studies, of which only 13 pertained to robotic neurosurgery. Spinal fixation was the most common intervention (six studies), followed by Deep Brain Stimulation (DBS, two studies), Cochlear implants (two studies), laser ablation (LITT, one study), and endovascular embolization (one study). Most studies had industry sponsors (9/13 studies), while only five studies had hospital sponsors.

Conclusion:

Robotic neurosurgery is still in its infancy with less than half of the top programs offering robotic procedures. Future directions for robotics in neurosurgery appear to be focused on increased automation of stereotactic procedures such as DBS and LITT and robot-assisted spinal surgery.
ACTIVATION OF STRESS-OVERCOMING STRATEGIES OF FUTURE PRIMARY SCHOOL TEACHERS WITH THE HELP OF MUSIC
Authors: Сhernous Tetiana , Kalamazh Viktoriia
Published: August 2022

The article examines the use of music in the process of students’ implementation of stress-relieving strategies during the period of martial law. A theoretical analysis of musical means (imaginative music-making, therapeutic song-writing, active music-making, joint music-making, joint improvisation, music listening, integrative music therapy techniques, in particular using the Orff approach) as factors in the activation of stress-overcoming strategies was carried out. An empirical study of the structure of personal stress coping strategies of future teachers in war conditions was conducted with the help of a survey and the Coping Strategy Indicator (CSI) method by James H. Amirkhan. The optimal musical techniques for the activation of the mentioned strategies have been found out. According to the empirical study, it was found that the vast majority of students choose musical techniques in view of their positive effect on communication processes, activation of mechanisms of social and psychological adaptation, psychophysiology. Moreover, students choose musical techniques taking in consideration the influence on the processes of excitation and inhibition, self-awareness and self-regulation, and regulation of psycho-emotional and cognitive activity. The analysis of students’ stress-coping strategies indicates a significant advantage of the stress-coping tendency of ‘problem solving’ and ‘seeking social support’, which are considered to be more effective strategies in a stressful situation compared to the ‘avoidance’ strategy, which is not often used by students. Using Spielberger – Hanin State-Trait Anxiety Inventory (STAI) the dynamics of changes of anxiety levels as a result of the musical intervention were analyzed. Based on the results obtained, a positive relationship between musical techniques and the level of situational and personal anxiety was revealed. The tendency to decrease the level of situational anxiety is more pronounced compared to personal anxiety, which corresponds to the norms of response to stressful factors in the conditions of a war situation. According to the research results, a conclusion was made about the expediency of using certain musical techniques during the performance of stress-relieving strategies, in order to do certain tasks that ensure efficiency of their introduction.
DOMINANT COPING STRATEGIES IN STUDENTS OF MEDICAL COLLEGE
Authors: Yakovleva Mariia , Kalamazh Ruslana , Hilman Anna
Published: August 2022

The article presents the results of the ascertaining stage of the study of coping behaviour in students of medical college. The author carried out a theoretical analysis of generic concepts of sanogenic coping, such as sanogenic reflection, sanogenic thinking, coping strategies and coping behaviour. It has been investigated that the most frequent events that cause stress in medical college students are: the death of a close family member, changes in the financial situation, intersex relationships, starting college (for male respondents) and illnesses, changes in social activity, change of a place of residence, conflicts in a collective (dormitory), death of a family member or friend, change of a place of residence and study (for female respondents). The level of stress resistance was experimentally studied and coping strategies were chosen by students to overcome the current stressors. It has been found out that the threshold level of resistance to stress prevails in most students. Thus, students are forced to make a lot of effort and spend their own internal resources to fight against negative mental states that appear in the process of coping with stress. It was identified that there is a significant share of medical college students with low stress resistance – 25% of male respondents and 22% of female respondents, and quite a few individuals showed a high level of stress resistance – only 12% of male respondents and 12% of female respondents. It was found that problem-oriented coping and the search for social support are dominant among medical college students’ coping strategies; other types of strategies such as emotion-oriented coping, avoidance, and distraction are used somewhat less often by young people. It is emphasized that adaptive coping strategies contribute to effective coping with stressful situations. Based on the research, it was found that in most cases, the coping strategies chosen by the students led to an even greater increase in stress. Consequently, the problem of formation and development of productive copingstrategies among students of future medical workers remains relevant. The prospect of further research is the development of practical recommendations for effective coping with stressful and crisis situations in the activities of future medics.
Prototype of Lighting Intensity Administration in Work Room With Sound Control and Fuzzy Logic Control
Authors: Syafitri Nesi , Ibnu Faderi Raja , Suryani Des , Labellapansa Ause
Published: August 2022

The use of indoor and outdoor lighting systems that are still passive makes the use of electrical energy less efficient and classified as wasteful. From the problems that occur in the system that is running, the researchers need to develop a more dynamic system by utilizing the Tsukamoto FLC method and Arduino using voice control to adjust the intensity of the light in the room. After implementing as well as testing the system that has been made, namely the Prototype of Light Intensity Regulator in the Work Room With Voice Control and Fuzzy Logic Control using NodeMCU ESP8266, it is concluded that each component can function according to its function which can be controlled and monitored from the application, implements fuzzy logic control on nodemcu with time and activity input variables obtained from the android application while the room light intensity variable is obtained from the light sensor or LDR. The results of the fuzzy process will adjust the light which is controlled by nodemcu. With the fuzzy logic control in this system, it can adjust the light to the room conditions, making it much more efficient.
Reading Motivation and EFL Learners’ Vocabulary Development Against Interest in Learning English Moderated by Teacher Competence
Authors: Ibhar Muhalida Zia
Published: August 2022

Reading is critical for students of English as a foreign language. Apart from the four abilities that needed desire to grow, reading is one of the most critical skills in language acquisition. Therefore, this study aims to investigate reading motivation and EFL learners’ vocabulary development against interest in learning English moderated by teacher competence. The research participants were university students (ages 18) as many as 53 students in the Riau Province, Indonesia. This research was using quantitative methods. The data were collected using a questionnaire and analyzed using the SEM (Structural Equation Modeling) technique which was operated through the Warp PLS 3.2.7 program. Finding of this study revealed that there was a significant effect on student interest in learning with teacher competence as a moderating variable. The teacher should provide an interesting text for students, especially EFL students, so that students read the English text not because they are forced by their surroundings, but because they have an internal motive to complete the work.
Analisa Proses Bisnis Dan Model Bisnis Pada Platform E-commerce Syariah Salamin.Id
Authors: Putri Indah Permatasari  , Masruchin
Published: August 2022

Pesatnya perkembangan internet memunculkan inovasi konsep dan praktik dalam perdagangan secara elektronik atau disebut dengan e-commerce. Hal tersebut dapat menjadi peluang untuk mengoptimalkan implementasi model bisnis syariah dalam pengembangan platform e-commerce. Sementara yang menjadi objek penelitian adalah platform e-commerce syariah Salamin.id. Metode penelitian yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan deskriptif untuk mendeskripsikan dan menjelaskan bagaimana penerapan Bussines Model Canvas (BMC) pada platform e-commerce Salamin.Id. Teknik pengumpulan data dalam penelitian ini dilakukan secara langsung melalui wawancara pada pihak Salamin.Id. Penelitian ini bertujuan untuk mengetahui proses dan model bisnis yang ada pada e-commerce syariah Salamin.id yang menggunakan akad salam dan Bussines Model Canvas (BMC).  Dari penelitian ini akan digambarkan mengenai permodelan bisnis dari platform salamin.id dan bagaimana implementasi akad salam dapat dilakukan pada bisnis platform salamin.id. Hasil penelitian mengemukakan bahwa pengembangan platform ecommerce harus memperhatikan model bisnisnya terlebih dahulu sehingga dapat mengetahui jenis akad apa yang harus diimplementasikan sesuai dengan nilai kepatuhan syariah. Hasil penelitian menunjukkan 9 komponen platform design yang menggambarkan aktivitas bisnis pada platform Salamin.id.
High-Pressure promoted Nazarov-like electrocyclization enables access to trans-4,5-Diamino-Cyclopent-2-enones bearing Electron-Poor Anilines
Authors: Mateus Afonso Carlos Alberto , Cavaca Lídia , Ravasco João , Gomes Rafael
Published: August 2022

Unlike secondary alkyl amines and electron-rich anilines, secondary electron-poor anilines are challenging amine sources to explore the chemical space of Lewis acid-catalyzed condensation-based transformations with furfural. In this work is reported the efficient synthesis of trans-4,5--diamino cyclopentenones (DCP) using a high-pressure promoted Nazarov-like electrocyclization of Stenhouse salts arising from the Sc(III)-catalyzed condensation of furfural with secondary electron-poor anilines. The reaction enables access to otherwise difficultly accessible DCP and compatibility with a large scope of alkyl and aryl secondary amines. A 2 to 18-fold increase in yields for electron-poor anilines was highlighted by the use of this approach in the synthesis of a pharmacologically active compound.
Switchable organocatalysis from N-heterocyclic carbene-carbodiimide adducts with tunable release temperature
Authors: Pham Le Dung , Smith-Sweetser Red , Dewey Carolyn , Lamb Jessica
Published: August 2022

N-heterocyclic carbenes (NHCs) are powerful organocatalysts, but their air- and moisture-sensitivity often require in situ generation of the free carbene from a stable precursor (i.e., “masked” NHC). Carboxylate adducts are the most well-studied thermally-labile NHC precursor, but catalyst activation is irreversible and the simplicity of the CO2 mask results in the NHC structure controlling both catalytic activity and activation temperature. Herein, we develop new NHC masks based on carbodiimides (CDIs), which have two nitrogen substituents that can tune catalyst release orthogonally from reactivity. Using a common imidazolylidene NHC, we show that CDI masks can be used to achieve switchable organocatalysis and that small electronic perturbations to the CDI substituents (i.e., phenyl versus para-tolyl) result in >10 °C difference in activation temperature without changing the NHC structure. This platform will enable more precise control over NHC organocatalysis than previous systems.
Electrochemical exfoliation of two-dimensional siligene SixGey; material characterization and perspectives for lithium-ion storage
Authors: Kovalska Evgeniya , Wu Bing , Liao Liping , Mazanek Vlastimil , Marek Ivo , Lajaunie Luc , Sofer Zdenek
Published: August 2022

Two-dimensional (2D) silicene-germanene alloy - siligene (SixGey), a novel single-phase material has attracted increased attention due to its two-elemental low-buckled composition and unique physics and chemistry. This new 2D material has the potential to address the challenges caused by low electrical conductivity and the environmental instability of corresponding monolayers. Yet, siligene structure was studied in theory, demonstrating the material’s great electrochemical potential for energy storage applications. The synthesis of free-standing siligene remains challenged and therefore hinders the research and application of this material. Herein we pioneer non-aqueous electrochemical exfoliation of a few-layer siligene from Ca1.0Si1.0Ge1.0 Zintl phase precursor. The procedure was conducted in an oxygen-free environment applying 3.8 V potential. The obtained silicene exhibits a high-quality, high uniformity, and excellent crystallinity; the individual flake is within the micrometer lateral size. The 2D SixGey was further explored as an anode material for lithium-ion storage. Two types of anode have been fabricated and integrated into lithium-ion battery cells, namely 1) siligene_graphene oxide sponge, and 2) siligene_multi-walled carbon nanotubes. The as-fabricated batteries both with/without siligene exhibit similar behaviour, however referring to the increase in the electrochemical characteristics of SiGe-integrated batteries by 10%. The corresponding batteries exhibit 1145.0 mAh·g-1 specific capacity at 0.1 A·g-1. The SiGe-integrated batteries demonstrate a very low polarization confirmed by their good stability after 50 working cycles and a decrease in the solid electrolyte interface level that occurs after the first discharge/charge cycle. We anticipate the growing potential of emerging two-component 2D materials and their great promise for energy storage and beyond.