bluuebunny/crossref_metadata_2025 huggingface dataset:
Spontaneous regression of a vein of Galen aneurysmal malformation in a pediatric patient: illustrative case
Authors: Kumar Kevin K. , Fornoff Linden E. , Dodd Robert L. , Marks Michael P. , Hong David S.
Published: May 2021

BACKGROUND

Vein of Galen aneurysmal malformations (VGAMs) are rare congenital intracranial vascular lesions that represent 30% of all pediatric vascular anomalies. These lesions are associated with severe manifestations, including congestive heart failure, hydrocephalus, and spontaneous hemorrhage. The mainstay of management is medical stabilization followed by endovascular embolization of the lesion. Although VGAM was first reported in 1937, there are few published cases demonstrating spontaneous regression of the lesion.

OBSERVATIONS

The authors report the case of a 31-month-old female who presented with an incidentally found VGAM. After initial evaluation, including magnetic resonance imaging and angiography, the patient was lost to follow-up. Upon her return to the clinic at age 12 years, the previously identified VGAM was absent, indicative of involution of the lesion. The patient remained asymptomatic and met appropriate developmental milestones during this interval.

LESSONS

This report adds a rare case of the spontaneous resolution of VGAM to the literature. This case may suggest the presence of VGAMs that are asymptomatic, undetected, and regress within the pediatric population. Future studies may benefit from identifying imaging and angiographic findings predictive of spontaneous regression. There may be a role for conservative management in particular cases of asymptomatic and medically stable children with VGAMs.
Vascular occlusion in a previously unaffected territory after treatment with intravenous plasminogen activator: illustrative case
Authors: Sugie Akira , Yamada Makoto , Yokoyama Kunio , Miyake Tomoaki , Ito Yutaka , Tanaka Hidekazu , Nomura Yukiya , Fujita Masutsugu , Nakatani Toshio , Kawanishi Masahiro
Published: May 2021

BACKGROUND

Intravenous tissue plasminogen activator (IV t-PA) is effective for the treatment of distal artery occlusion. However, after the use of IV t-PA, vascular occlusion in unaffected territories may occur. Early recurrent ischemic stroke (ERIS) is defined as the occurrence of new neurological symptoms that suggest the involvement of initially unaffected vascular territories after intravenous thrombolysis (IVT). The authors reviewed the cases of ERIS that occurred within 24 hours after treatment with IVT.

OBSERVATIONS

A 75-year-old woman with occlusion in the M2 segment of the left middle cerebral artery (MCA) was treated with IV t-PA. However, 360 minutes later, the patient presented with occlusion in the M1 distal segment of the contralateral side, the right MCA, which was recanalized by endovascular treatment. Her modified Rankin Scale score was 4; however, aphasia was not observed. She was transferred to a rehabilitation hospital after 3 months.

LESSONS

ERIS is an extremely rare but catastrophic event. The underlying mechanism of ERIS most likely involves the disintegration and subsequent scattering of a preexisting intracardiac thrombus. Hence, caution must be used when managing not only hemorrhagic complications but also ischemic complications after IV t-PA. Endovascular management may be the only effective treatment for this type of large vessel occlusion.
A modern multidisciplinary approach to a large cervicothoracic chordoma using staged en bloc resection with intraoperative image-guided navigation and 3D-printed modeling: illustrative case
Authors: Pertsch Nathan J. , Leary Owen P. , Camara-Quintana Joaquin Q. , Liu David D. , Niu Tianyi , Woo Albert S. , Ng Thomas T. , Oyelese Adetokunbo A. , Fridley Jared S. , Gokaslan Ziya L.
Published: May 2021

BACKGROUND

Cervicothoracic junction chordomas are uncommon primary spinal tumors optimally treated with en bloc resection. Although en bloc resection is the gold standard for treatment of mobile spinal chordoma, tumor location, size, and extent of involvement frequently complicate the achievement of negative margins. In particular, chordoma involving the thoracic region can require a challenging anterior access, and en bloc resection can lead to a highly destabilized spine.

OBSERVATIONS

Modern technological advances make en bloc resection more technically feasible than ever before. In this case, the successful en bloc resection of a particularly complex cervicothoracic junction chordoma was facilitated by a multidisciplinary surgical approach that maximized the use of intraoperative computed tomography–guided spinal navigation and patient-specific three-dimensional–printed modeling.

LESSONS

The authors review the surgical planning and specific techniques that facilitated the successful en bloc resection of this right-sided chordoma via image-guided parasagittal osteotomy across 2 stages. The integration of emerging visualization technologies into complex spinal column tumor management may help to provide optimal oncological care for patients with challenging primary tumors of the mobile spine.
Primary cranial vault germinoma in a 23-year-old man: illustrative case
Authors: Lauren Christopher , Argie Donny , Malelak Elric B. , Mawardy Reza , Suranta Samuel E. , Junaidy Vito M. , Firmansyah Yohanes
Published: May 2021

BACKGROUND

Germinoma is the most common type of germ cell tumor that develops intracranially. Germinomas usually grow in the midline structures, such as the pineal and suprasellar regions, and are rarely found in other locations. To the best of the authors’ knowledge, no previous research has reported on growth of this tumor in the cranial vault.

OBSERVATIONS

The authors reported an unusual case of primary cranial vault germinoma in a young adult. Macroscopically, the tumor had a solid-soft consistency and grayish color with brownish spots on the surface. The histological examination revealed anaplastic cells with round, hyperchromatic, pleomorphic nuclei; prominent nucleoli; and abundant, clear cytoplasm, arranged in lobules and sheets that were infiltrated by lymphocytes and separated by fibrous connective tissue. These findings were consistent with the histopathological characteristics of germinoma.

LESSONS

Primary cranial vault germinoma is a unique tumor because no previous research has reported any growth in that location. It should be considered one of the differential diagnoses of lesions located over the cranial vault. Histopathological examination is still the primary modality for diagnosing these tumors and excluding other differential diagnoses.
Intraoperative contrast-enhanced ultrasound for intramedullary spinal neoplasms: patient series
Authors: Barkley Ariana , McGrath Lynn B. , Hofstetter Christoph P.
Published: May 2021

BACKGROUND

Primary intramedullary spinal tumors cause significant morbidity and death. Intraoperative ultrasound as an adjunct for localization and monitoring the extent of resection has not been systematically evaluated in these patients; the effectiveness of intraoperative contrast-enhanced ultrasound (CEUS) remains almost completely unexplored.

OBSERVATIONS

A retrospective case series of patients at a single institution who had consented to the off-label use of intraoperative CEUS was identified. Seven patients with a mean age of 52.8 ± 15.8 years underwent resection of intramedullary tumors assisted by CEUS performed by a single attending neurosurgeon. Histopathological evaluation revealed 3 cases of hemangioblastoma, 1 case of pilocytic astrocytoma, 2 cases of ependymoma, and 1 case of subependymoma. Contrast enhancement correlated with gadolinium enhancement on preoperative magnetic resonance imaging. Intraoperative CEUS facilitated precise lesion localization and myelotomy planning. Dynamic CEUS studies were useful in demonstrating the blood supply to lesions with a dominant vascular pedicle. Regardless of contrast uptake, the differential enhancement between spinal cord tissue and neoplasm assisted in determining interface boundaries.

LESSONS

Intraoperative CEUS constitutes a useful adjunct for the intraoperative delineation of contrast-enhancing intramedullary tumors and in vivo confirmation of gross-total resection. Systematic investigation is needed to establish the role of CEUS for resection of intramedullary spinal tumors of various pathologies.
Endovascular selective hypothermia facilitates giant aneurysm clipping: illustrative case
Authors: Mattingly Thomas K. , Lopez-Ojeda Pablo , Arango Miguel , Harle Chris , Kakani Nirmal , Allen Peter , Lehrbass Barbara , Lownie Stephen P.
Published: May 2021

BACKGROUND

The authors present a case of selective hypothermia used for neuroprotection during clipping of a giant partially thrombosed middle cerebral artery (MCA) aneurysm. Although these cases have traditionally required deep hypothermic cardiac arrest, this case illustrates a novel and entirely endovascular solution that avoids cardiac standstill and whole-body cooling.

OBSERVATIONS

This is, to the authors’ knowledge, the first case in human surgery of a catheter-based selective hypothermic circuit used to facilitate MCA trapping for almost 30 minutes. Core temperatures never dropped below 34°C, and the patient recovered uneventfully and has been well for over 5 years.

LESSONS

The technical nuances and physiological changes unique to selective hypothermia are discussed.
Repair of internal carotid artery injury with aneurysm clip during endoscopic endonasal surgery: illustrative case
Authors: Fustero de Miguel David , López López Laura Beatriz , Avedillo Ruidíaz Amanda , Orduna Martínez Javier , Casado Pellejero Juan , Moles Herbera Jesús Adrián
Published: May 2021

BACKGROUND

One of the most feared and dangerous scenarios that can appear during an endoscopic endonasal surgery (EES) is the iatrogenic injury of the internal carotid artery (ICA). Several methods, along with a variety of outcomes, have been described to deal with this complication. To the authors’ knowledge, this is the first report on the use of a Yasargil-type aneurysm clip to solve an ICA injury, preserving the artery’s patency and having a long-term follow-up. The authors discuss the advantages and disadvantages of other vessel preservation techniques compared with clipping.

OBSERVATIONS

A visually impaired 56-year-old woman was diagnosed with a giant nonfunctional pituitary tumor that invaded the sphenoidal sinus, anterior and posterior ethmoidal cells, and both cavernous sinuses, with suprasellar extension and optochiasmatic compression. The patient underwent EES, and during the final resection phase her left ICA was injured, with massive hemorrhage.

LESSONS

ICA injury during endoscopic skull base surgery carries high mortality and morbidity; it is essential to maintain carotid flow when possible to avoid short-term and long-term consequences. There are several techniques depicted in the literature to deal with this situation. The authors report the use of a Yasargil mini-clip to deal with the injury for a positive outcome: primary hemostasis, vessel preservation, and no postoperative complications.
Giant pituitary macroadenoma of stem cell origin: illustrative case
Authors: Asuzu David T. , Burke Rebecca M. , Hakim Jeffrey , Coss Dylan , Park Min S. , Payne Spencer C. , Jane John A.
Published: May 2021

BACKGROUND

Giant pituitary macroadenomas with a diameter >4 cm are rare tumors, accounting for only about 5% of pituitary adenomas. They are more difficult to maximally resect safely owing to limited access as well as encasement of adjacent structures. Acidophil stem cell adenomas are rare immature neoplasms proposed to derive from common progenitor cells of somatotroph and lactotroph cells. These adenomas comprise about 4.3% of surgically removed pituitary adenomas. No previous reports have described acidophil stem cell adenomas that grow to the size of giant macroadenomas. This rare entity poses special challenges given the need for maximal safe resection in an immature neoplasm.

OBSERVATIONS

The authors report a 21-year-old female who presented with 3 years of progressive visual decline and a giant macroadenoma. She underwent endoscopic transsphenoidal surgery for decompression. Given the tumor size and involvement of adjacent critical structures, gross-total resection was not achieved. The authors review the literature on giant pituitary adenomas and provide a discussion on clinical management for this rare entity.

LESSONS

The authors present a very rare case of a giant pituitary adenoma of acidophil stem cell origin and discuss the technical and management challenges in this rare entity.
Asymptomatic superficial siderosis after posterior fossa tumor resection: illustrative case
Authors: Goyal Anshit , Nesvick Cody L. , Spear Joshua A. , Daniels David J.
Published: May 2021

BACKGROUND

Superficial siderosis of the central nervous system is a rare syndrome notable for the presence of hemosiderin deposition due to chronic, repetitive hemorrhages into the subarachnoid space.

OBSERVATIONS

The authors presented a case of superficial siderosis in a 14-year-old girl. It arose as a late postoperative complication after resection of a medulloblastoma. Despite the patient being asymptomatic, surveillance imaging demonstrated diffuse hemosiderin deposition within the cerebellar folia and cisternal segments of cranial nerves VII and VIII on gradient echo (GRE) sequences. Formal audiometric testing demonstrated bilateral loss of high-frequency tone recognition consistent with early sensorineural hearing loss. A pseudomeningocele due to multiple dural defects was identified as the likely cause, and definitive surgical repair was performed. Intraoperatively, the presence of blood-tinged cerebrospinal fluid confirmed a diagnosis of superficial siderosis.

LESSONS

This case highlighted the potential need to routinely include GRE or susceptibility-weighted sequences in postoperative surveillance imaging after resection of pediatric posterior fossa tumors.
Wall Following Control System with PID Control and Ultrasonic Sensor for KRAI 2018 Robot
Authors: Iqbal Muhamad Hamam , Aji Wahyu Sapto
Published: May 2021

Indonesian Abu Robot Contest (KRAI) in 2018 with the theme "Throwing a Blessing Ball". The main purpose of this robot is to be able to navigate automatically in an area that is bordered by walls to complete the mission. The main problem with the robot is the navigation system. The application of PID control in the wall following system has been able to make robot movements smooth, responsive, and fast. In this study, PID control aims to smooth the movement of the robot while walking along the wall in the race arena. The PID parameter is obtained from the results of tuning with the trial and error method, the values of KP = 3, KI = 0, and KD = 5. At the PWM 150 set point the value of the ultrasonic sensor distance reading to the object in the form of a wall with an average error of 4.4. cm. At the PWM 200 set point the value of the ultrasonic sensor distance reading to the object in the form of a wall with an average error of 0.4 cm. At the PWM 250 set point the value of the ultrasonic sensor distance reading to the object in the form of a wall with an average error of 0.8 cm. This error does not have an effect on the performance of the wall following system, because the system only uses the distance value reading data with a decimal value in front of the comma. So it can be concluded that the wall following system which is designed using ultrasonic sensors with measurement error that occurs is zero.
Robot Operating System (ROS) in Quadcopter Flying Robot Using Telemetry System
Authors: Faiq Hatta Mohammad Iqbalul , Satya Widodo Nuryono
Published: May 2021

In this study implementing odometry using RVIZ on a quadcopter flying robot that uses the Pixhawk Cube firmware version 3.6.8 as the sub-controller. Then the Lenovo G400 laptop as the main-controller as well as the Ground Control Station using the ubuntu 16.04 Linux operating system. The ROS platform uses the Kinetic and MAVROS versions as a quadcopter platform package using MAVlink communication with the telemetry module. The odometry system was tested using Rviz as navigation for Quadcopter movements in carrying out movements that follow movement patterns in certain shapes and perform basic robot movements. Data were collected using a standard measuring instrument inclinometer as a measurement of the slope of the robot and visualization RVIZ as a visual display of the odometric robot. The results of the research obtained are that the flying robot can maneuver according to the shape on the RVIZ according to the movements carried out directly at the airport, as well as the effect of the roll angle on the quadcopter (negative left roll, positive right) and the pitch angle on the quadcopter (negative forward pitch, the pitch returns positive).
An Optimally Configured HP-GRU Model Using Hyperband for the Control of Wall Following Robot
Authors: Rehman Khan Abdul , Tamoor Khan Ameer , Salik Masood , Bakhsh Sunila
Published: May 2021

In this paper, we presented an autonomous control framework for the wall following robot using an optimally configured Gated Recurrent Unit (GRU) model with the hyperband algorithm. GRU is popularly known for the time-series or sequence data, and it overcomes the vanishing gradient problem of RNN. GRU also consumes less memory and is computationally more efficient than LSTMs. The selection of hyper-parameters of the GRU model is a complex optimization problem with local minima. Usually, hyper-parameters are selected through hit and trial, which does not guarantee an optimal solution. To come around this problem, we used a hyperband algorithm for the selection of optimal parameters. It is an iterative method, which searches for the optimal configuration by discarding the least performing configurations on each iteration. The proposed HP-GRU model is used on a dataset of SCITOS G5 robots with 24 sensors mounted. The results show that HP-GRU has a mean accuracy of 0.9857 and a mean loss of 0.0810, and it is comparable with other deep learning algorithms.
Numerical analysis of seismic behavior of square concrete filled steel tubular columns
Authors: Phan Hao Dinh
Published: May 2021

This paper presents a numerical analysis of the seismic behavior of square concrete filled steel tubular (CFST) columns. Finite element analysis (FEA) models in ABAQUS software were used to simulate a series of columns subjected to axial compression and cyclic lateral loading. The CFST columns were simulated using nonlinear tri-dimensional (3-D) finite elements for the infilled concrete, and nonlinear two-dimensional (2-D) finite elements for the steel tube. The feasibility of the FEA model has been validated by published experimental results. The validated FEA model was further extended to conduct parametric studies with various parameters including axial load level (n), width-to-thickness ratio of steel tube (B/t), and concrete strength. The numerical analysis results reveal that with the same B/t and constitute materials, the higher the axial compression, the lower the shear strength and deformation capacity were. The thicker steel wall (B/t = 21) resulted in higher strength and larger deformation capacity of the column. Increasing concrete strength helped to significantly develop the column’s shear strength in all cases. Meanwhile, it just led to an increase in deformation capacity in some cases depending on n and B/t. This study also reveals that the square CFST columns with B/t of 21 satisfy the seismic performance demand in high seismic zones (ultimate interstory drift ratio (IDRu) not less than 3% radian) under the two axial load levels, 0.35 and 0.45, but the columns with B/t of 28 satisfy the above demand under just one axial load level of 0.35.

Keywords:

square concrete filled steel tubular (CFST) columns; finite element analysis (FEA) model; width-to-thickness ratio (B/t); high axial load level; seismic behavior.
Solution Blow Spinning (SBS): A Promising Spinning System for Submicron/Nanofibre Production
Authors:   Department of Textile Engineering, Bangladesh University of Business and Technology, Dhaka-1216, Bangladesh, Khan Md. Khalilur Rahman , Hassan Mohammad Naim ,   Department of Textile Engineering, Khulna University of Engineering and Technology, Khulna-9203, Bangladesh
Published: May 2021

Submicron/nanofibres possess great potential for application in different areas because of their amazingly high surface area-to-weight ratio. The demand for fabrication of such fibres on a huge scale is increasing with the fast improvement of nanotechnology. Traditionally, nanofibre fabrication methods have intrinsic faults, limiting their application in industry. Solution blow spinning (SBS) is a viable option for producing adaptable and conformable submicron/nanofibre mats on a variety of surfaces. The technique can be employed to produce submicron/ nanofibres with only a simple commercial airbrush, a concentrated polymer solution, and a compressed gas source. It depends on the high velocity of decompressed air that allows the rapid stretching and evaporation of the solvent from a polymeric solution jet at the outlet of the concentric nozzles system. Along with recent advancements, the importance and drawbacks of the solution blow spinning system in comparison to other methods, such as electrospinning and melt blowing, are briefly discussed. Furthermore, the mechanisms of co-axial SBS spinning and micro SBS spinning system for submicron/nanofibre fabrication are also described. Drawbacks and research challenges of SBS are also addressed in this paper.
Perancangan Turbin Angin Jenis Helical untuk Sistem Pembangkit Listrik
Authors: H. Anwar Nur Rahmah
Published: May 2021

Penelitian ini bertujuan untuk memenuhi kebutuhan listrik di jalan raya dan untuk mengurangi ketergantungan terhadap bahan bakar fosil. Proses perancangan sistem pembangkit listrik jenis helical dilakukan dengan mengidentifikasi kebutuhan, spesifikasi teknis, perancangan konsep, seleksi desain dan analisis perhitungan daya serta analisis simulasi putaran turbin angin. Energi listrik yang dihasilkan oleh turbin helical ini disimpan ke dalam aki kering untuk dimanfaatkan sebagai sumber listrik penerangan lampu jalan. Hasil seleksi desain diperoleh rancangan turbin angin jenis helical dengan tinggi sudu 1.000 mm, lebar sudu 151 mm. diameter rotor 750 mm. Hasil analisis daya yang dihasilkan oleh dua unit turbin sebesar 3.319,69 Wh. Energi listrik yang tersimpan di dalam aki kering 24 V kapasitas 70 Ah sebagai sumber energi penerangan lampu jalan selama 12 jam untuk 2 buah lampu LED 55 W 24 Volt DC dengan total beban pemakaian sebesar 1.518 Wh. Turbin ini dapat digunakan pada wilayah tertentu yang dilalui oleh banyak kendaraan.
KENT PARKLARINDAN SAĞLANAN EKOSİSTEM HİZMETLERİNE YÖNELİK KULLANICI ALGISININ İNCELENMESİ
Authors: DOYGUN Neslihan
Published: May 2021

Bu çalışmada, kent parklarından sağlanan ekosistem hizmetlerine yönelik kullanıcı algılarının Q metodoloji yardımıyla değerlendirilmesi amaçlanmıştır. Q metodoloji, bir konu üzerinde kişiler tarafından ileri sürülen düşüncelerin benzer ve farklı yönlerinden yola çıkılarak bakış açılarının sınıflandırılması işlemine dayanmaktadır. İzmir kentinde yer alan üç park için yürütülen çalışmada ekosistem hizmetleri birer ifade halinde kullanıcıların görüşüne sunulmuş, uygulamada iki farklı bakış açısı belirlenmiştir. Parklardan sağlanan ekosistem hizmetleri arasında, her iki bakış açısında da kültürel ekosistem hizmetleri ağırlık kazanmıştır. Bunun nedeninin, parkların yaşama ve çevreye yönelik sosyo-kültürel etkilerinin, ekolojik süreçlerdeki rolüne nazaran daha kolay gözlemlenebilir nitelikte olmasından kaynaklandığı düşünülmektedir. Faktörlerde hangi ifadeler üzerinde hemfikir olunduğu incelendiğinde, 1 nolu faktörde ön plana çıkan ifadelerin tamamı olumlu iken, 2 nolu faktörde olumsuz ifadelerin de yer aldığı görülmüştür. Çalışma ile elde edilen sonuçların, kent parklarını iyileştirmeye yönelik uygulamalara katkı sağlaması, ekosistem hizmetlerinin değerlendirilmesi ve Q metodoloji ile gerçekleştirilecek benzer araştırmalara örnek teşkil etmesi beklenmektedir.
KURAK VE YARIKURAK ALANLARDA TÜPLÜ VE ÇIPLAK KÖKLÜ DİKİLEN KARAÇAM (Pinus nigra Arnold. subsp. pallasiana) FİDANLARININ 5 YILLIK DİKİM BAŞARISININ DEĞERLENDİRİLMESİ; KÜTAHYA-TAVŞANLI ÖRNEĞİ
Authors: TONGUÇ Fatih , UÇAR Sena
Published: May 2021

Anadolu karaçamı (Pinus nigra Arnold. subsp. pallasiana (Lamb.) Holmboe) stepe en çok sokulan ve çok farklı topraklar üzerinde yetişebilmesi nedeniyle doğal yayılış alanları içerisinde olduğu kadar, orman dışı alanların ağaçlandırılmasında da kullanılan türler arasında yer almaktadır. Yapay gençleştirme çalışmalarında çıplak köklü olarak dikilen fidanların dikim maliyetleri düşük olmasına rağmen arazideki performanslarının belirlenmesi de büyük önem arz etmektedir. Mevcut çalışma Kütahya Orman Bölge Müdürlüğü, Tavşanlı Orman İşletme Müdürlüğü, Yaylacık ve Tunçbilek İşletme Şeflikleri sınırları içerisinde toprak yapısı benzer alanlar üzerinde 2013 yılında dikilen 2+0 çıplak köklü ve 2+0 tüplü karaçam fidanlarının 5 yıllık arazi dikim başarılarının belirlenmesi amacıyla gerçekleştirilmiştir. T-testi sonuçlarına göre araziye tüplü olarak dikilen fidanların boy, kök boğazı çapı, son yıl sürgün boyu ile çıplak köklü olarak dikilen fidanlarda tespit edilen değerler arasında istatistiksel olarak önemli (p<0.05) farklılıklar bulunmuştur. Fidanların dikimlerden beş yıl sonraki arazideki tutma oranları da çıplak köklü dikilen fidanlarda % 81, tüplü olarak dikilenlerde ise % 95 olarak belirlenmiştir. Tüplü olarak dikilen karaçam fidanlarında; ortalama fidan boyu 162.19 cm, kök boğazı çapı 4.21 cm ve son yıl sürgün boyu 41.81 cm olarak belirlenmiştir. Çıplak köklü olarak dikilen fidanlarda; ortalama fidan boyu 131.61 cm, kök boğazı çapı 3.68 cm ve son yıl sürgün boyu 34.88 cm olarak daha düşük tespit edilmiştir.
SURVIVAL OF MYELOMA PATIENTS RECEIVING BISPHOSPHONATES IN A "REAL LIFE" EXPERIENCE: POTENTIAL IMPACT ON RISK OF OSTEONECROSIS OF THE JAW (ONJ)
Authors: Monaco Federico , Fusco Vittorio , Limberti Giulia , Fasciolo Antonella , Ferrero Elisabetta , Brigo Paola , Tartara Daniela , Baraldi Anna , Catania Gioacchino , Ladetto Marco
Published: May 2021

Background. Expected survival of myeloma patients increased in recent decades, after introduction of new drugs and strategies. Median survival has been reported about 5 years, but it is very variable, according to age, comorbidities, disease stage, etc. 

Almost all myeloma patients receive bisphosphonates as antiresorptive treatment (with denosumab recently approved as an alternative) shortly after diagnosis, and 1%-15% of them develop Osteonecrosis of the Jaw (ONJ), within some years of treatment (or observation). Expected survival of myeloma patients can influence the choice of ONJ treatment among possible options. 

Methods. Charts of myeloma patients receiving bisphosphonates and observed at the Haematology Unit of Alessandria Hospital in years 2005-2020 have been reviewed. Kaplan-Meier actuarial survival was evaluated. 

Results. Median survival from the start of antiresorptive treatment of 244 patients was 5.36 years - with 79%, 69%, 60%, 52% of patients alive at 2, 3, 4, 5 years.  At 7 and 10 years, 41.3% and 30.2% of patients were alive. 

ONJ occurred in 7 patients, after a median of 6.3 years (range 0.5-13.2) from the start of treatment. Mean survival from the ONJ diagnosis time of those 7 patients was 2.9 years (range 0.5-6.0).

Conclusions: Expected survival of myeloma patients in a “real life” setting after the start of antiresorptive treatment is medially long in terms of years, with a large portion of patients exposed at risk of developing ONJ for more than 5 years.  A surgical treatment of ONJ is warranted, being expected survival not so short to hamper jawbone surgery.
Is It Still Profitable to Grow Lychee in Florida?
Authors: Evans Edward , Degner Robert , Crane Jonathan , Rafie Ray , Balerdi Carlos
Published: May 2021

In the following analysis, we examine developments within the U.S. lychee industry and focus on the costs and returns of producing lychee in Florida to determine whether farmers can still make a profit from growing this commodity. This is EDIS document FE496, a publication of the Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. Published November 2004. 

https://edis.ifas.ufl.edu/fe496
MODIFIKASI PEMBUAT MOL LIMBAH ORGANIK BAHAN PRAKTIKUM DI LABORATORIUM POLITEKNIK PERTANIAN NEGERI PAYAKUMBUH
Authors: Maiza Linda Tri , Yubniati Yubniati , Hermansyah Rio
Published: May 2021

Salah satu pemanfaatan limbah organik dari sisa praktikum di lingkungan Politeknik Pertanian Negeri Payakumbuh adalah sebagai bahan pembuatan MOL. MOL dijadikan bioaktivator pembuatan kompos dan pupuk organik cair yang dapat digunakan kegiatan budidaya tanaman di lingkungan Institusi. Alat pembuat MOL memakai ember plastik bertutup,  menghasilkan kualitas MOL masih rendah, ditandai dengan aroma MOL berbau busuk, larutan yang dihasilkan banyak endapan , serta tidak efisien dalam saat panen. Penelitian ini bertujuan untuk mengetahui kinerja alat  pembuatn MOL yang sudah dimodifikasi.Pengamatan meliputi dari segi kualitas aroma, kebersihan, efisiensi waktu dan tenaga. Pengujian kinerja  pembuat alat pembuat MOL yang belum dimodifikasi dan sudah di modifikasi dengan memakai bahan sayuran dan buah-buahan. Dari hasil pengujian  menunjukkan bahwa alat modifikasi pembuat MOL yang menggunakan saringan dan kran menghasilkan kualitas  MOL yang baik, ditandai larutan MOL dengan aroma khas dan penampakan larutannya bersih, tidak menimbulkan kendala saat panen dari segi waktu dan tenaga. Dapat disimpulkan bahwa alat pembuat MOL yang di modifikasi memakai saringan dengan menambahkan kran dibagian dasar wadahnya memberi tingkat kualitas MOL lebih baik.
PENGARUH PENGGUNAAN ZPT ALAMI DAN BUATAN TERHADAP PERTUMBUHAN SETEK TANAMAN DELIMA (Punica granatum L.)
Authors: Tanjung Tiffany Yuandara
Published: May 2021

Delima (Punica granatum L.) adalah tanaman yang berasal dari Persia (Iran), Afganistan dan wilayah pegunungan Himalaya yang biasa dimanfaatkan sebagai tanaman pekarangan dan obat-obatan, dimana buahnya mengandung berbagai nutrisi dan vitamin yang  dimanfaatkan untuk kesehatan dan berbagai jenis penyakit. Perbanyakan vegetatif stek tanaman delima dilakukan untuk menyediakan bibit tanaman dalam jumlah yang lebih banyak dan dalam waktu yang singkat serta memiliki sifat yang sama seperti induknya. Zat pengatur tumbuh (ZPT) yang diberikan berperan dalam mengatur percepatan pertumbuhan stek dengan kandungan auksin dan sitokinin. Tujuan dari percobaan ini adalah untuk: mengetahui pengaruh penggunaan berbagai jenis ZPT terhadap pertumbuhan stek tanaman delima, mendapatkan jenis ZPT yang terbaik terhadap pertumbuhan stek tanaman delima. Percobaan tugas akhir ini dilakukan pada tanggal 24 Februari sampai 11 April 2020 di kebun percobaan UPTD BBI PPH SUMBAR. Parameter yang diamati dari percobaan ini: persentase tumbuh (%), jumlah tunas, panjang akar dan jumlah akar. Hasil dari percobaan ini adalah persensate tumbuh yang baik terdapat pada perlakuan buah pisang dan rapid root yaitu 80%, jumlah tunas terbanyak pada perlakuan buah pisang 2,6 tunas, panjang akar yang terpanjang pada perlakuan air kelapa 1,4 cm, jumlah akar terbanyak pada perlakuan air kelapa 6 akar. Kesimpulan dari perbanyakan ini adalah Penggunaan berbagai jenis ZPT memiliki pengaruh terhadap pertumbuhan stek delima, penggunaan ZPT buah pisang memiliki hasil yang baik pada persentase tumbuh dan jumlah tunas. ZPT air kelapa memiliki hasil yang baik untuk panjang dan jumlah akar yang diamati hingga 5 minggu setelah tanam. Berdasarkan kesimpulan disarankan untuk menggunakan ZPT rapid root.
The Islamic Movement in Israel: Ideology vs. Pragmatism
Authors: Schwartz David , Galily Daniel
Published: May 2021

This study aims to present the Islamic Movement in Israel, its ideology and pragmatism. With progress and modernization, the Islamic movements in the Middle East realized that they could not deny progress, so they decided to join the mainstream and take advantage of technological progress in their favor. The movement maintains at least one website in which it publishes its way, and guides the audience. Although these movements seem to maintain a rigid ideology, they adapt themselves to reality with the help of many tools, because they have realized that reality is stronger than they are. The main points in the article are: The Status of Religion in Israel; The Legal Status of Muslim Sharia in Israel; Personal status according to Israeli law; The establishment of the Islamic Movement in Israel – Historical Background; The crystallization of movement; Theoretical Background – The Theory of Pragmatism; Ideology and goals of the Islamic Movement in Israel; The background to the split in the movement – the opposition to pragmatism; How the ideology of the movement is expressed in its activity? The movement’s attitudes toward the Israeli elections, the Oslo Accords and the armed struggle against Israel; How does pragmatism manifest itself in the movement’s activities?
A Comparative Study on University Admission Predictions Using Machine Learning Techniques
Authors: Golden Prince , Mojesh Kasturi , Devarapalli Lakshmi Madhavi , Reddy Pabbidi Naga Suba , Rajesh Srigiri , Chawla Ankita
Published: May 2021

In this era of Cloud Computing and Machine Learning where every kind of work is getting automated through machine learning techniques running off of cloud servers to complete them more efficiently and quickly, what needs to be addressed is how we are changing our education systems and minimizing the troubles related to our education systems with all the advancements in technology. One of the the prominent issues in front of students has always been their graduate admissions and the colleges they should apply to. It has always been difficult to decide as to which university or college should they apply according to their marks obtained during their undergrad as not only it’s a tedious and time consuming thing to apply for number of universities at a single time but also expensive. Thus many machine learning solutions have emerged in the recent years to tackle this problem and provide various predictions, estimations and consultancies so that students can easily make their decisions about applying to the universities with higher chances of admission. In this paper, we review the machine learning techniques which are prevalent and provide accurate predictions regarding university admissions. We compare different regression models and machine learning methodologies such as, Random Forest, Linear Regression, Stacked Ensemble Learning, Support Vector Regression, Decision Trees, KNN(K-Nearest Neighbor) etc, used by other authors in their works and try to reach on a conclusion as to which technique will provide better accuracy.
Sentimental Analysis of YouTube Videos
Authors: Baravkar Aditya , Jaiswal Rishabh , Chhoriya Jayesh , Tekwani Prof. Bhanu
Published: May 2021

YouTube is the second most popular social media platform with two billion users. Every minute around thousand hours of videos are uploaded. On an average people watch one billion hours of YouTube videos per day. Every youtuber want their video to get popular and make best possible efforts. However, video can crawl at the top of search with help of clickbait, etc. which compromises the content of video. There are videos whose relevancy and quality are top-notch but cannot make to top five or ten. People watching such videos interact by commenting, liking and subscribing. Especially in education category, viewers interested in watching long marathons or tutorial series have to make choice wisely to avoid wastage of time. To get favorable videos on top list, the sentiments of comments, no. of likes, views, comments is considered. The objective is to provide well analyzed and relevant educational videos to the budding students by reducing valuable search time.
Development of Text Clustering Method with K-Means for Analysis of Text Data
Authors: Wadnare R. J. , Sherekar Dr. S. S. , Thakare Dr. V. M.
Published: May 2021

Clustering is a widely used unsupervised data mining technique. In clustering, the main aim is to put similar data objects in one cluster and dissimilar in another cluster. The k-implies is the most famous clustering algorithm because of its effortlessness. But the performance of the k-means clustering algorithm depends upon the parameter selection. Parameter selection like number of cluster and initial cluster center are key of k-means algorithm. Distance augmentation method, density method quadratic clustering methods are utilized to initial cluster selection. This paper examination five unique methods, for example, improved k-means text clustering algorithm, revisiting k-means, LMMK algorithm, SELF-DATA architecture, Clustering Approach for Relation e.t.c. But these techniques have some limitations. To improve these approach, this paper has proposed the development of text clustering method with k-means for analysis of text data.
A Review of Encryption Techniques Used in Cloud Computing
Authors: Tandel Parth , Shubhrant Abhinav , Sohani Mayank
Published: May 2021

We can say that we are surrounded by the computing world from every nook and corner. Cloud Computing is deemed as the most fundamentally changing phenomenon happening in Information Technology. But with great perks, comes great challenges as well, especially in the field of data security and privacy protection. The Cloud Service Providers take over chunks of private data from users for providing better functionalities. But for the sake of privacy and protection, this sensitive data should be encrypted and then outsourced to the cloud consoles.

Since traditional cloud computing is performed on plaintext, many encryption algorithms were applied in the cloud for security purposes and ‘encrypted’ data was stored in the cloud from then on. This change gives fruition to a new type of encryption technique called Homomorphic Encryption. Primarily, the paper will focus on a subtype of Homomorphic Encryption called Fully Homomorphic Encryption. The objective of the paper is to propose a method to convert the sequentially processing Fully Homomorphic Encryption into parallel processing Fully Homomorphic Encryption using a Parallel Computing concept called Partitioning and thereby producing a better performing Fully Homomorphic Encryption.
Sentiment Analysis : A Review and Comparative Analysis on Colleges
Authors: Chandurkar Toshita , Tijare Dr. Pritish
Published: May 2021

Sentiment analysis is the process of detecting positive and negative sentiment in text. It’s often used by businesses to detect sentiment in social data, gauge brand reputation, to understand it and make better. Sentiment analysis models focus on polarity (positive, negative and neutral) and even intentions (interested v. not interested). Depending on how you want to interpret feedback and queries, you can define and tailor your categories to meet your sentiment analysis needs. This paper focuses the reviews of college which are an important form of opinion contents. The basic objective of this work is to classify every sentence’s semantic orientation (e.g. positive, negative and neutral) of the reviews. It is a really useful analysis since we could possibly determine the overall opinion about the colleges.
Moisture Level Sensor Using Node-Red
Authors: Chandra Maradani Bhuvana , Puneeth Korada , Dubey Gaurav
Published: May 2021

This paper presents the implementation of an Internet of Things (IoT) application that performs the Moisture level sensing through node MCU and Raspberry Pi, and data transfer to the Cloud of the Amazon Web Services or Raspberry Pi. The implementation is done using programming the Node MCU using Embedded C, Raspberry pi is Operated using Raspbian operating system and AWS EC2 Internet of Things platform based on the Node-RED tool installed on the Raspberry Pi and the AWS EC2. The Interconnection of data from the Node MCU to Raspberry Pi is done by MQTT Data Transfer Protocol and Mosquitto Protocol.
Financial Analysis Of Students With The Application Of E-Learning
Authors: Yulyanah Yulyanah , Kurniawati Desi
Published: May 2021

This study aims to find out the views of students with the application of E-Learning learning during the pandemic. This research method is qualitative descriptive with the research subject of D3 Accounting students of the Faculty of Economics, Pamulang University in the 2020-2021 school year. The data was obtained from a questionnaire in the form of a goggle form given to respondents. The number of respondents who filled as many as 123 respondents.. The results of the study concluded that for online learning income there was a 6% decrease in > from Rp. 1,000,000 when offline 38% to 24% when online. As for expenses - expenses that increase are utility costs, internet quota costs and consumption costs for costs that decrease when online learning is for transportation costs. From the results of the analysis of income and expenditure dominant reponden tend to choose offline or offline learning as much as 59% of respondents.
Policy Forum: Re-Envisaging the Canada Revenue Agency—From Tax Collector to Benefit Delivery Agent
Authors: Petit Gillian , Tedds Lindsay M. , Green David , Kesselman Jonathan Rhys
Published: May 2021

In Canada, the tax system is not used just to raise revenue; it is also an important instrument for achieving various social policy objectives. As a result, the tax system has become closely intertwined with the income support system; it now serves as the delivery mechanism for many key income support benefits. As a benefit administration tool, the tax system has advantages, but it is also problematic. First, it relies on self-assessment, which means that the onus is on individual taxfilers to provide complete and accurate information to the government on the income taxes that they owe. However, persons who have no tax liability are not legally required to file tax returns, and therefore many may not do so. In the context of benefit delivery, the reliance on self-assessment risks missing many individuals who are eligible to receive income benefits. Second, individuals generally file a self-assessed tax return only once a year. As a result, the tax system could not respond to the dramatic in-year income shocks that occurred during the COVID-19 pandemic. We identify ways to modernize Canada's tax system and make it more responsive and streamlined for the purposes of benefit delivery. Reforms such as pre-filled tax forms and real-time reporting could greatly improve the ability of the Canada Revenue Agency to deliver income benefits, and the ability of the federal and provincial governments to meet social objectives, including those set out in Canada's and the provinces' poverty reduction strategies.
EKSTRAKSI PASIR SLIKAT (SILLICOND SAND) SEBAGAI MATERIAL SUBTRAT PADA SENSOR GAS DAN TURUNANNYA
Authors: Alamsyah Tossin
Published: May 2021

Pasir silika adalah material dari kristal silika (SiO2) dan senyawa lainnya yang mengandung material lain  selama proses deposisi, memiliki komposisi gabungan dari SiO2, Fe2O3, Al2O3, CaO, MgO, dan K2O.  Sensitivitas atau responsivitas suatu sensor gas dapat dipengaruhi oleh porositas pada permukaan substrat, umumnya substrat material dari sensor gas digunakan alumina (Al2O3) atau dioxside silikon (SiO2).Pada artikel  ini membahas tentang hasil proses sintering pada pasir silika yang bertujuan untuk mendapatkan struktur SiO2 yang baik, khusunya dalam parameter konduktivitas termal. Proses sintering dilakukan pada pasir silika dengan campuran almunium sulfat (AlSo4) pada 1600o untuk hasil kemudian tumbuk menjadi tiga (3) buah sampel yaitu sampel A ukuran  mesh 300, Sampel B ukuran mesh 500 mesh dan sampel C ukuran mesh  1000 mesh.Hasil pengamatan, jika tiga sampel dipanaskan (T) sampai 1000 , sampel C memiliki responsivitas tinggi untuk dibandingkan dengan sampel a dan b dengan rasio 5,7; 5,4 dan 4,8. Disimpulkan bahwa bahan substrat dengan ukuran mesh kecil  (sampel C, 1000) memiliki resistivitas termal yang tinggi dibandingkan dengan ukuran bahan mesh rendah , sampel A (mesh 300) dan  dan B(mesh 500).Akhirnya  ketika diimplementasikan dalam model sensor Gas CO, dihasilkan bahwa sample C dengan mesh 1000 memiliki thermal sensitivitas yang lebih besar dibandingkan dengan sampel B dan A
Handbuch der Praktiken im Sportunterricht im beruflichen und technologischen Unterricht mit der kostenlosen Anwendung Efe – Eptfis
Authors: Viana Valderi Nascimento , Fecury Amanda Alves , Oliveira Euzébio de , Dendasck Carla Viana , Dias Claudio Alberto Gellis de Mattos
Published: May 2021

Die Anwendung, EFE-EduFisEPT, dient als Unterstützung für Sportunterricht Schulaktivitäten, mit historisch-kritischer Pädagogik geschieht die Konfrontation der wissenschaftlichen Kenntnisse des Lehrers mit den empirischen Kenntnissen der Schüler, die Entwicklung einer neuen Vision und Aktion in der Gesellschaft. Der Zweck dieses Handbuchs ist es, den Sportlehrer über die Inhalte und Praktiken für Densport-Klassen in EPT und über die Funktionalität der kostenlosen Anwendung EFE – EPTFis zu führen. Mit seiner einfachen Benutzeroberfläche wird die Verwendung der Anwendung einfach und mit intuitiver Funktionalität. Dieses pädagogische Produkt existiert als Unterstützung für den Lehrer, um eine kritischere Sporterziehung zu entwickeln, die den Schüler jenseits des biologischen Wesens versteht, d.h. eines sozialen, politischen, kulturellen und historischen Wesens. In dem jede Klasse verstehen kann, dass die präsentierten Inhalte mit verschiedenen Dimensionen der Realität verknüpft sind und zu einer gesellschaftsbasierten Vision beitragen, die auf Werten und Einstellungen zum gemeinsamen Ziel basiert: Wissen, um weniger Ausschlüsse und Diskriminierungen zu erzeugen.
The Relationship Between Job Burnout and Job Satisfaction: Health Care Industry Perspectives
Authors: Muhammad Nur Anisa , Anuar Herman Shah
Published: May 2021

The healthcare industry is becoming one of the most growing concerns among people in Malaysia. This industry is expected to provide efficient and effective services to the community. This study is aimed to examine the relationship between the dimension job burnout, which includes emotional exhaustion, personal accomplishment, and depersonalization with job satisfaction among healthcare providers in the healthcare industry at the northern part of Malaysia. A quantitative methodology was applied in this study where 200 questionnaires had been distributed. Only 171 questionnaires were collected and returned back. Out of that number, only 156 questionnaires were fit to be analysed. It was found that all of the burnout dimensions (emotional exhaustion, depersonalization, and personal accomplishment) have a significant relationship to job satisfaction. Multiple Regression analyses have found that 2 of the independent variables had a negative relationship with job satisfaction (emotional exhaustion and depersonalization). Personal accomplishment is the most significant and had a strong relationship with job satisfaction. It is recommended for future research to conduct qualitative research to find diversity in the result, emphasising on other professions, including a firefighter, police officer, custom immigration officer, or any other enforcement profession which seems to have an issue with job burnout. It is challenging to conduct this research due to the geographical location since the location for this study is in the northern part of Malaysia. It involves many hospitals, clinics as well as patient-oriented personnel. On the other hand, future research may include a bigger number of medical and healthcare personnel all over Malaysia to get a better generalisation. A wider scope of the population will provide better findings that cover all spectrum of the healthcare provider.