bluuebunny/crossref_metadata_2025 huggingface dataset:
Formulation and In vitro Percutaneous Permeation and Skin accumulation of Voriconazole Microemulsified Hydrogel
Authors: Prajapati Mahendra , Shende Shradha , Jain Vivek , Gupta Akhil , Kumar Goyal Manoj
Published: November 2021

The aim of the present study was to prepare and evaluate voriconazole microemulsified hydrogel. The voriconazole microemulsified is prepared by Water Titration Method. In which voriconazole microemulsified incorporated with hydrogel, Blank gels of different polymers were prepared by distilled water. Finally, the carbopol gel was prepared by dispersing 0.5% carbopol w/v and 0.5% aloe vera powder in 100 ml of water with stirring on mechanical stir. Additionally, for preservation of formulations 0.8% methyl paraben was mixed. Oil phase was selected by dissolving the voriconazole pure in different oils, oleic acid, castor oil, coconut oil, olive oil, cooten seed mineral oil and soya oil. Oleic acid was selected on the basis of higher solubility of voriconazole in it. Combination of surfactant and co-surfactant was selected on clear visual observation. Span - 40: propylene glycol in ratio 1:1 and 2:1 selected for further preparation of microemulsion. From the study F-8, F-9, F-10, F-14 and F-15 were selected for further studies. Though F-16, F-17, F-18, F-19 and F-20 formulations are also stable, but rejected due to high concentration of surfactant can cause skin irritation, skin burning and/or other complications. Characterization of selected voriconazole microemulsion formulations were evaluated under various parameters like Droplet size, Zeta potential, Poly Dispersity Index (PDI) and (%) Drug content all results showed.
Formulation development and in vitro Evaluation of sustained release matrix tablets of Cefpodoxime proxetil
Authors: Bhavani A. , Hemalatha B. , Padmalatha K.
Published: November 2021

The present focus is on the development of sustained release formulations due to its inherent boons. There are several advantages of sustained release drug delivery over conventional dosage forms like improved patient compliance, reduction in fluctuation and increased safety margin of potent drug. The present study was aimed to prepare a sustained drug delivery system to design a controlled release oral dosage form of Cefpodoxime proxetil. The sustained release matrix tablets of Cefpodoxime proxetil were prepared by wet granulation and evaluated for different parameters such as weight variation, drug content, thickness, hardness, friability and In vitro release studies. The in vitro dissolution study was carried out for 12 hours using USP (Type- II) paddle apparatus in hydrochloride (0.1N) as dissolution media for first 2 hours and phosphate buffer (pH 6.8) for next 10 hours. Based on the in vitro dissolution data, formulation F8 was selected as the best formulation from Cefpodoxime proxetil formulations (F1 – F9) as the drug release was retarded up to 12 hours with 96.29 % and followed zero order release kinetics & drug release mechanism was diffusion.
Chemical Composition of Oroxylum indicum: A Review
Authors: Chowdhary Yogita
Published: November 2021

Root bark of sonapatha is an astringent, tonic, anti-diarrhoeal, diuretic, anodyne, and is used to cure dropsy. It is an ingredient of ‘dashamoolarishta’ of Ayurvedic medicine. Stem bark is anti-rheumatic. An infusion of bark powder is diaphoretic. Tender fruits have spas- molytic, carminative, and stomachic properties, while seeds are purgative.it is a medium-sized, soft-wooded tree attaining a height of 10–16 m. Stem bark is dull brown in colour; leaves are broad, 60–120 cm in length and pinnately compound. Leaflets are ovate, wavy, and acuminate. Leaf fall occurs during winter season (January) each year. The tree is recognized by ternately bipinnate leaves. The root bark contains chrysin, baicalein, dehydrobaicalein, and orozylin. Stem bark possesses flavonoids such as oroxylin, baicalein, scutelarin and 7-rutinoside, chrysin, and p-coumaric acid. Heartwood yields β-sitosterol and isoflavone-prunetin. Root bark of sonapatha is an astringent, tonic, anti-diarrhoeal, diuretic, anodyne, and is used to cure dropsy. It is an ingredient of ‘dashamoolarishta’ of Ayurvedic medicine. Stem bark is anti-rheumatic. An infusion of bark powder is diaphoretic. Tender fruits have spas- molytic, carminative, and stomachic properties, while seeds are purgative. It is a medium-sized, soft-wooded tree attaining a height of 10–16 m. Stem bark is dull brown in colour; leaves are broad, 60–120 cm in length and pinnately compound. Leaflets are ovate, wavy, and acuminate. Leaf fall occurs during winter season (January) each year. The tree is recognized by ternately bipinnate leaves. The root bark contains chrysin, baicalein, dehydrobaicalein, and orozylin. Stem bark possesses flavonoids such as oroxylin, baicalein, scutelarin.
Short Review on Novel Dosage Form
Authors: Sonawane Tushar N. , Dhangar Pradip D. , Patil Sagar D , Shaikh Azam Z.
Published: November 2021

Novel Drug Delivery Systems are one of the widely use delivery system in the presence scenario. Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. In the form of a Novel Drug Delivery System an existing drug molecule can get a new life. The novel drug delivery system is Increases bioavailability and it Can be used for long-term treatments of chronic illness, Sustained maintenance of plasma drug levels as well as it Decreased adverse drug effects in the total amount of drugs required thus reducing side effects it Improved patient compliance due to reduction in number and frequency of doses required. There is less damage sustained by normal tissue due to targeted drug delivery. In this paper our main focus to give the throughout knowledge of some newer (Novel drug delivery system) to understand the concept of the Novel dossage form.
Bioelectric Medicine: Magicall Tools for Treatment of Many Diseases
Authors: Madane Vikram B. , Mali Sasmit N.
Published: November 2021

Bioelectronic medicine is a relatively new area that focuses on developing methods for treating diseases that do not need medications. Bioelectronic medicine treatments are now possible thanks to a small embedded system that produces and delivers frequent digital doses to nerve bundles, resulting in a disease-fighting effect that can last hours or days and is based on mechanisms similar to drug therapies. Although this may sound like science fiction, electronic brain and nerve stimulators are now presence applicable to treat so many of ailments, including epilepsy, Parkinson's disease, and bladder control. Progress in treating such disorders has opened up possibilities for boosting memory, improving eyesight, strengthening a shaky gait, and even improving a golfer's swing. Those self-improvement dreams may be a long way off, but bioelectronic medicine is gaining traction as a new way to treat difficult diseases. What distinguishes bioelectronic medicine is its biological effect on the body, which goes beyond symptom management to treat the underlying condition by using the body's own mechanisms. With promising early results in many trials and further trials ongoing, bioelectronic therapies are likely to be accepted for clinical use within the next few years. To make this advancement possible, forward-thinking scientists, engineers, doctors, and innovators with specialised talents combined old and new discoveries in ways no one had before.
Dạy học tập đọc cho học sinh lớp 4, 5 theo hướng khai thác các kỹ năng để cảm thụ văn bản
Authors: Nguyễn Văn Bản , Nguyễn Thị Hồng Vân
Published: November 2021

Kĩ năng đọc là một trong bốn kĩ năng thể hiện năng lực ngôn ngữ có vai trò vô cùng quan trọng trong học tập và giao tiếp của mỗi người cũng như học sinh tiểu học. Dạy tập đọc cho học sinh lớp 4, lớp 5 ở tiểu học không chỉ hướng tới mục tiêu học sinh biết đọc thông mà còn hướng tới việc các em phải hiểu và cảm thụ sâu sắc về văn bản. Bài báo này đề xuất dạy tập đọc cho học sinh lớp 4, 5 theo hướng khai thác kĩ năng đọc (đọc thầm - hiểu; đọc - tóm tắt; đọc - hiểu; đọc - cảm thụ văn bản) nhằm giúp học sinh rèn luyện tốt các mức độ của kĩ năng đọc và cảm thụ được các tác phẩm văn chương góp phần hình thành và phát triển nhân cách.
Thực trạng và biện pháp nâng cao chất lượng đội ngũ cán bộ quản lý các trường trung học phổ thông ở thành phố Cần Thơ trong thời kỳ đổi mới
Authors: Phạm Văn Dũng
Published: November 2021

Trong những năm qua, đội ngũ cán bộ quản lý các trường trung học phổ thông ở thành phố Cần Thơ đã cùng với ngành giáo dục và đào tạo hoàn thành tốt nhiệm vụ được giao. Tuy nhiên, trước yêu cầu đổi mới giáo dục phổ thông, đội ngũ này bộc lộ bất cập, hạn chế; bài báo phác họa thực trạng về đội ngũ và đề xuất biện pháp nâng cao chất lượng đội ngũ cán bộ quản lý các trường trung học phổ thông ở thành phố Cần Thơ hiện nay.
Thực trạng và biện pháp xây dựng văn hoá nhà trường của Trường Cao đẳng Sư phạm Sóc Trăng
Authors: Mai Thị Yến Lan , Nguyễn Ngọc Nghiệp
Published: November 2021

Văn hóa nhà trường có ảnh hưởng đến tất cả các hoạt động diễn ra trong nhà trường. Xây dựng văn hóa nhà trường lành mạnh, hướng tới sự phát triển bền vững, góp phần không ngừng nâng cao chất lượng đào tạo. Tuy nhiên, việc xây dựng văn hóa nhà trường chưa được quan tâm và đầu tư đúng mức. Trên cơ sở tìm hiểu thực trạng, bài viết này tập trung đề xuất một số biện pháp xây dựng văn hóa nhà trường ở Trường Cao đẳng Sư phạm Sóc Trăng.
Một số biện pháp dạy và ôn tập môn Lịch sử lớp 12 ở trường phổ thông theo hình thức trắc nghiệm khách quan
Authors: Hoàng Việt Trung
Published: November 2021

Bắt đầu từ năm học 2016 - 2017, Bộ Giáo dục và Đào tạo đã ban hành Quy chế thi trung học phổ thông quốc gia 2017 với hình thức khá mới mẻ so với những năm học trước. Lần đầu tiên học sinh làm bài thi tổ hợp khoa học tự nhiên và khoa học xã hội bằng hình thức trắc nghiệm khách quan. Để đáp ứng yêu cầu đổi mới hình thức kiểm tra đánh giá, đòi hỏi phải có sự đổi mới về phương pháp dạy và học. Bài viết này đề cập đến một số biện pháp dạy và ôn tập môn Lịch sử 12 theo lối thi mới. Nhất là hình thành các kĩ năng làm bài trắc nghiệm cho học sinh.
Ảnh hưởng của vốn xã hội đến khả năng tìm việc làm của sinh viên tốt nghiệp
Authors: Phạm Xuân Quỳnh , Cao Văn Hơn
Published: November 2021

Ngày càng có nhiều bằng chứng khoa học cho thấy nguồn vốn xã hội đóng vai trò quan trọng trong mối liên hệ qua lại giữa cung và cầu trong thị trường lao động. Bên cạnh các phương pháp tìm kiếm việc làm chính thức (qua các kênh quảng cáo, qua các đơn vị dịch vụ việc làm, ứng tuyển trực tiếp), thông qua vốn xã hội người lao động còn sử dụng các mối quan hệ xã hội (người thân, bạn bè) như một kênh không chính thức hiệu quả. Nghiên cứu khảo sát tình trạng việc làm của 304 sinh viên kinh tế tốt nghiệp tại Trường Đại học An Giang. Kết quả nghiên cứu cho thấy vốn xã hội có ảnh hưởng đến khả năng tìm việc làm của sinh viên tốt nghiệp. Bên cạnh đó, nghiên cứu còn mô tả mối liên hệ giữa mạng lưới quan hệ xã hội đến đặc điểm việc làm tìm được.
Các nhân tố ảnh hưởng đến quyết định chọn xin việc vào Trường Đại học An Giang
Authors: Trần Thị Hằng Ni
Published: November 2021

Nghiên cứu được thực hiện nhằm tìm hiểu các nhân tố ảnh hưởng đến quyết định chọn xin việc vào Trường Đại học An Giang. Dữ liệu khảo sát dựa trên ý kiến của 350 giảng viên, chuyên viên hiện đang công tác tại Trường Đại học An Giang theo phương pháp lấy mẫu phi xác suất. Qua các bước phân tích Cronbach’s Alpha, EFA, tương quan và hồi quy, kết quả phân tích cho thấy có 6 nhân tố tác động đến quyết định chọn xin việc vào Trường Đại học An Giang xếp theo thứ tự tầm quan trọng như sau: (1) Thương hiệu và uy tín của tổ chức; (2) Sự phù hợp giữa cá nhân và tổ chức; (3) Thu nhập và phúc lợi; (4) Cơ hội đào tạo và thăng tiến; (5) Mức trả công và hình thức trả công và (6) Tác động từ gia đình, bạn bè. Mô hình nghiên cứu giải thích được 57,3% về sự tác động của 6 nhân tố nói trên đến quyết định chọn xin việc vào Trường Đại học An Giang.
Giải pháp khai thác các sản vật địa phương tỉnh An Giang trong phát triển du lịch
Authors: Lê Văn Hiệu , Dương Thanh Xuân
Published: November 2021

Từ nhiều năm qua, việc phát triển du lịch gắn với các vùng sản vật địa phương đã được triển khai và nhân rộng ở nhiều địa phương trên cả nước, nhất là ở một số tỉnh, thành thuộc vùng Đồng bằng sông Cửu Long. An Giang là một trong những tỉnh có nhiều sản vật địa phương độc đáo, điển hình, góp phần làm đa dạng sản phẩm du lịch cho tỉnh nói riêng và vùng Đồng bằng sông Cửu Long nói chung.Tuy nhiên, thời gian qua, ngành du lịch của An Giang chưa khai thác có chất lượng và hiệu quả các sản vật địa phương này. Do đó, mục đích chính của nghiên cứu là đánh giá tiềm năng và đề xuất những giải pháp nhằm góp phần khai thác hiệu quả các sản vật địa phương phục vụ phát triển du lịch của tỉnh An Giang.
Therapeutic Pathways of Vesicovaginal Fistula, From the Past to the Future: A Mini-Review
Authors: Chrisostomos Sofoudis , Georgios Tsoukalos , Konstantinos Zioris
Published: November 2021

Over the last decade, innovation of medical interventions concerning less radical surgery consists cornerstone of therapeutic management. Among gynecologic surgical procedures, medical experience and completion of educational curve lead to the decrease of potential post-operative complications. Vesicovaginal Fistula (VVF) represent ultimate medical injury in cases of total laparoscopic or abdominal hysterectomy. The aim of our study, consists of primary detection of such cases, assiduous imaging depiction, and ultimate therapeutic strategy. New technical innovations and less radical intervention consist of necessary conditions to establish proper therapeutic mapping.
Reviewer Acknowledgements for Environmental Management and Sustainable Development, Vol. 10 No. 4
Authors: Young Jenny
Published: November 2021

Environmental Management and Sustainable Development (EMSD) would like to thank the following reviewers for reviewing manuscripts from August 1, 2021, to November 1, 2021. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether EMSD publishes their work, appreciate the helpful feedback provided by the reviewers. Macrothink Institute appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. Aristotulus Ernst Tungka, University of Sam Ratulangi Manado, IndonesiaChristiane do Nascimento Monte, Universidade Federal Fluminense, BrazilChuck Chuan Ng, Xiamen University Malaysia, MalaysiaDastun Gabriel Msuya, Sokoine University Of Agriculture, TanzaniaHayssam Mohamed Ali, King Saud University, EgyptJoão Fernando Pereira Gomes, Instituto Superior de Engenharia de Lisboa, PortugueseNuralam Hossain, Chongqing University, ChinaOylum Gokkurt Baki, Sinop University, TurkeyPankaj Maheshwari, College of Engineering, University of Nevada, Las Vegas, USATateda Masafumi, Toyama Prefectural University, Japan
Medios normativos concernientes a la salud mental perinatal
Authors: Sanz María Jesús , Casado Demetrio
Published: November 2021

El objetivo de este artículo es acopiar fundamentos normativos a la crianza infantil basada en la familia. Para ello se examinaron normas jurídicas y técnicas de especial relevancia para la salud mental perinatal y general generadas por: Naciones Unidas, Organización Mundial de la Salud, órganos de la Unión Europea y del Estado Español. Se trata de documentos sobre derechos humanos, salud y salud mental. El resultado es copioso y convergente. De ello se concluye que la creación de unidades madre-bebé, planteada por ASMI WAIMH España, cuenta con respaldo normativo genérico.
Notas de campo en salud mental perinatal: una breve experiencia latinoamericana
Authors: Hernández Franco Andrea , Nuñez Jara Karla
Published: November 2021

El Ministerio de Salud Pública de Ecuador ha promulgado 25 normativas para la atención del COVID-19, creadas de manera interdisciplinaria, procurando establecer, entre todas las aristas que la pandemia ha abierto, las recomendaciones que los profesionales de la salud perinatal deben seguir para el manejo y cuidado de la salud de las mujeres y sus neonatos con sospecha o confirmación de COVID-19, durante los ciclos vitales de la gestación, el nacimiento (vaginal o cesárea), posparto inmediato y lactancia. Además de estas recomendaciones, Ecuador cuenta con la Normativa ESAMYN que, a través de sus 24 pasos, busca garantizar el buen nacer y buen parir, legado importante para una sociedad cuya Constitución basa sus fundamentos en el saber ancestral y el Sumak Kawsay. Sin embargo, la realidad de las mujeres en toda su diversidad, y particularmente en el ámbito perinatal, no llega a tener la relevancia necesaria para que los tomadores de decisiones entiendan y atiendan la emergencia social que propiciará la pandemia. Los efectos secundarios del aislamiento y la inequidad del acceso a salud y educación rebotarán en la salud integral de nuestros bebés, niños y niñas. «Esta pandemia ha hecho que se intensifiquen todas las barreras de desigualdad presentes en la salud materna en la región», asegura Carmen Martínez, gerenta regional para América Latina y el Caribe del Centro de Derechos Reproductivos. Muchas veces estas barreras están condicionadas por el ánimo, criterio personal (incluso religioso) y formación del profesional que atiende. La atención está limitada a un paradigma reduccionista, que parece desconocer que somos seres integrales, bio-psico-socio-espirituales, que necesitamos afecto y contención para crecer y estar sanos. El devenir madre requiere un entorno especial, con características puntuales. El acompañamiento y tratamiento (psicológico y emocional) tanto para la madre, el padre y el bebé, son una necesidad antes, durante y después de este evento único. Sin embargo, no está adecuadamente comprendido e interiorizado por los profesionales y redes de atención a la infancia y familia. Y es que la salud mental materna y paterna son indicadores claves para la crianza saludable y salud mental del bebé. La familia es la base de la sociedad, la madre es la base de la familia. Las siguientes notas de campo buscan informar sobre las realidades de las mujeres gestantes y de los neonatos, previo y pos-pandemia, evidenciar la necesidad de acompañamiento emocional e información antes, durante y después del nacimiento, y el impacto de estos en el desarrollo de la maternidad.
Alianzas por la salud mental perinatal
Authors: Palau Subiela Pascual
Published: November 2021

Se trata de la descripción de tres Alianzas por la salud mental perinatal: la anglófona del Reino Unido, la francófona de Francia-Suiza-Luxemburgo-Bélgica y la hispanohablante de España-Hispanoamérica, todas ellas inscritas en la Alianza Mundial por la Salud Mental Materna.
Las unidades madre-bebé / padres-bebé en europa y las redes psiperinatales
Authors: Palau Subiela Pascual
Published: November 2021

Este texto sintetiza algunos de los avances realizados a nivel europeo en el campo de la salud mental perinatal e infantil en las últimas décadas y, de manera especial, en la atención pre y postparto de las mujeres y hombres en Unidades Madre-Bebé y Padres-bebé, mediante redes interdisciplinares psiperinatales y procedimientos de detección e intervención antenatal y postnatal, en el área Francófona de Europa.
Construyendo la infancia: casa verde, un proyecto de prevención, apoyo y seguimiento para hijos de personas con trastorno mental o inestabilidad emocional
Authors: Del Amo Raquel , Castejón Miguel Ángel , Holguín Gloria , Peinado Ricardo , Rodríguez Carlos , Sessé Elisa , Vallespín Teresa
Published: November 2021

OBJETIVOS: Se describe el Proyecto CASA VERDE de Fundación Manantial (Madrid, España) y sus resultados que desde 2011 facilita que los padres con trastorno mental puedan ejercer los roles parentales con sus hijos desde el embarazo hasta los 5 años, asegurando su adecuado desarrollo evolutivo. MÉTODO: Se parte de la investigación realizada por Fundación Manantial con la Universidad Complutense de Madrid, dirigida por Muñoz y Panadero en 2010, que dio cuenta de cómo hasta un 43% de los padres con un trastorno mental severo perdía la tutela de sus hijos, para justificar la necesidad de un proyecto como CASA VERDE. Se describen sus principales intervenciones con los adultos y los niños, así como el fundamento de las mismas y los mecanismos de evaluación y seguimiento del desarrollo de los niños. RESULTADOS: Tras nueve años de trabajo y con 118 familias atendidas, cuyos padres y madres estaban diagnosticados de psicosis, de trastorno de personalidad, de depresión y otros trastornos adaptativos, solo se retiró la custodia de sus hijos a una familia. CONCLUSIONES: El Programa CASA VERDE ha puesto de manifiesto la capacidad de las personas con diagnósticos psiquiátricos severos para cuidar de forma adecuada a sus hijos, desde el embarazo hasta los 5 años, siempre que ellos puedan ser cuidados y apoyados cuando lo necesitan, igual que nos ocurre a cualquiera de nosotros.
De las frühe hilfen a las unidades madre-bebé. El modelo alemán para el apoyo durante los primeros años de vida
Authors: Moral Javier
Published: November 2021

El objetivo de este texto es mostrar diferentes estructuras de los servicios asistenciales alemanes de atención a la perinatalidad, desde las redes nacionales de ayuda conocidas como las Frühe Hilfen a las Unidades Madre-Bebé, con el fin de mostrar un modelo europeo de asistencia a la perinatalidad y de este modo apoyar conceptualmente la creación de éstas en nuestro territorio nacional.
Efectos en la madre de la separación forzada de su bebé por orden judicial en el contexto de enfermedad mental
Authors: Bonifacino Nahir , Pérez-Martínez Carla
Published: November 2021

La separación forzada del bebé de sus padres por orden judicial es una situación de gran complejidad que genera repercusiones psicológicas profundas en todos sus protagonistas. Las normas internacionales concernientes a la protección de menores destacan invariablemente la prioridad del apoyo a la familia, sea en forma económica o de atención domiciliaria y psicológica, como instrumento prioritario para preservar la integridad del menor dentro de su marco de pertenencia familiar, considerando en último lugar y exclusivamente ante circunstancias probadas de extrema gravedad, la necesidad de adoptar medidas que lleven a su desarraigo de su ámbito familiar. En este contexto, la situación de padres con trastorno mental es contemplada en el ordenamiento jurídico español dentro de una línea de «desamparo involuntario», al considerarse que esta condición expone por sí misma al menor a un riesgo. Aunque no exista negligencia consciente o voluntaria de los padres, según las normas vigentes, esta situación puede llevar a la separación del niño de su entorno familiar. Desde hace varias décadas se analizan en profundidad los efectos que tiene en la salud mental y el desarrollo neuropsicológico infantil la separación temprana del niño en relación a su madre o a sus padres, pero, por el contrario, el estudio de los efectos que esta separación tiene en la madre y también en el padre no ha recibido hasta el momento suficiente atención. Nos proponemos indagar sobre esta temática, para lo cual recurriremos a datos epidemiológicos sobre la maternidad en personas con trastornos mentales y a estudios cualitativos que describen las experiencias de madres ante la separación forzada de su bebé en el contexto de enfermedad mental.
Clínica puerperal: blues del parto, depresión post-parto y psicosis puerperal. Definición, sintomatología, factores de riesgo y vivencia emocional
Authors: López Serra Manuela
Published: November 2021

En el presente texto se pretende abordar de manera teórica y descriptiva la clínica puerperal: los síntomas y factores de riesgo, las repercusiones en las interacciones más tempranas y su posterior impacto en el desarrollo del psiquismo del niño, así como también, la vivencia emocional de la maternidad desde el punto de vista de la madre. Se ha realizado una búsqueda de información en español y en inglés en las siguientes bases electrónicas: Medline, Pubmed, PsycInfo, Elsevier y Google Scholar. También, en libros específicos de depresión postparto y maternidad, en dos guías monográficas sobre Psiquiatría Perinatal y en material audiovisual del Máster Oficial de Psicopatología Perinatal. Los manuales de diagnóstico generales DSM y CIE dificultan el correcto diagnóstico de la clínica puerperal por su rigidez en las categorías que describen. La Psiquiatría Perinatal sí define específicamente el blues del parto, la depresión postparto y la psicosis puerperal con una prevalencia, respectivamente, de 50%, 10-15% y 0,1-0,2%. Es de vital importancia seguir incidiendo en el correcto diagnóstico de dichos trastornos, así como en el acompañamiento a las familias para poder favorecer su bienestar integral y reducir al máximo las repercusiones en las interacciones tempranas y el posterior impacto en el desarrollo del psiquismo del niño.
Informe sobre la revisión de planes y estrategias de salud mental de las comunidades autónomas en relación con la salud mental perinatal
Authors: Castejón Miguel Ángel , Sanz María Jesús
Published: November 2021

Con el objetivo de conocer, en una primera aproximación, la situación de la atención a la salud mental perinatal en España, se revisaron los planes de Salud Mental de las Comunidades y Ciudades autónomas cuyos resultados se ofrecen en este trabajo. De esta revisión se concluye que las Comunidades y Ciudades autónomas no cuentan con ningún plan específico para la atención a la salud mental perinatal, aunque sí existen algunas medidas en varios de los planes que guardan alguna relación con la misma y se incluyen en este texto.
Neurobiofisiología del vínculo y proceso mental en el recién nacido
Authors: Pedreira Massa José Luis
Published: November 2021

Las conductas de apego y el proceso de vinculación componen un paradigma de marco referencial para la comprensión de las dinámicas que acontecen en la primera infancia y que tienen una repercusión a medio y largo plazo, por lo que contribuye a la comprensión de los procesos mentales y de la intervención psicoterapéutica. Siendo unos conceptos que emergieron de la observación clínica, se han encontrado sustratos neurofisiológicos que avalan, con suficiencia metodológica, las conclusiones de la teoría del apego y fundamentan la denominación de «nuevo paradigma» para la interacción madre-bebé. Se destaca la importante función de la oxitocina para establecer el apego humano, apareciendo la acción de otras sustancias como las feromonas y los corticoides.
Los costes de los problemas mentales perinatales no atendidos se traducen en consecuencias para los niños y gastos económicos para el estado
Authors: Hernández Murillo Margarita , Aseguinolaza Chopitea Asier
Published: November 2021

Las enfermedades mentales perinatales son un importante problema de salud pública, que tienen una repercusión en el bienestar maternofilial y en los costes sanitarios, educacionales y jurídicos de un país. Basados en la experiencia de las unidades madre-bebé del sistema británico, se quiere visibilizar la necesidad de implantación de recursos especializados para la atención de enfermedades mentales perinatales, para reducir un sufrimiento evitable a la madre y su bebé, disminuir el impacto en los niños de procesos psicopatológicos en mujeres gestantes y en puérperas, y realizar una inversión económica en recursos especializados que a corto y medio plazo reduzcan los costes de los trastornos mentales perinatales, como depresión, ansiedad y psicosis, para el Estado
Age-Related Vestibular Dysfunction with Motion Sensitive Vertigo and Risk of Fall in Adults
Authors: Muneeb Muhammad , Shafee Iram , Waris Sadaf , Manzoor Taqdees
Published: November 2021

Background: This ageing is physiological process associated with vestibular dysfunction. The incidence of vestibular problems increases with age and can lead to drops, dropping risk, lack of confidence, pain and depression. Vestibular disorder is commonly characterized by vertigo or body discomfort (look and aggravation of postural stability) (a sense of spinning movement). In older adults with a fall history, peripheral vestibular disorders are among the most frequently known and widespread vestibular dysfunctions. Aim: To associate vestibular dysfunction and motion sensitive vertigo and risk of fall in adults. Methodology: Cross sectional study with convenient non- random sampling. For tests has been applied for screening vestibular dysfunction. If a participant shows 2 tests positive have vestibular dysfunction. SPSS 21 is used for data analysis. Results: Highly significant results between association of age with motion sensitive and age with fall efficacy scale P value is less than 5. Results are also significant between MSQ and FES-1. Conclusion: After conducting this research it has been concluded. That age-related vestibular dysfunction significantly associated with motion sensitive vertigo and risk of fall. As with the age people are more concerned about fall Keywords: vestibular dysfunction, vertigo, risk of fall in adults
Effect of Core Stability Exercises with Conventional Physiotherapy in Reducing Pain among Patients with Non-Specific Low Back Pain: RCT
Authors: Mumtaz Sara , Javed Ahsan , Mustansar Alishba , Gul Nadia , Saleem Maham , Latif Waqas , Laique Talha
Published: November 2021

Low backache is common among urban society. It is one of the main reasons for activity limitation and absenteeism from work Purpose: To compare role of swiss ball-based core stability exercise and conventional physiotherapy among patients of non-specific low backache in reducing pain and improving function Study Design: Randomized clinical trial Methodology: Current project was conducted at Ehsan Rehab Physiotherapy Clinic and Mumtaz Bukhtawar Trust Hospital, Lahore. Patients (n=74) aging between 25-50 years with nonspecific low backache were randomized into 2 groups. Thirty-seven patients were present in each of Group A and in Group B. Group A was treated with conventional physiotherapy treatment (Controlled Electrotherapy Treatment along with Conventional Exercises). Group B was treated with (Controlled Electrotherapy Treatment along with Core Stability Exercises on Swiss Ball). Oswestry disability index and numeric pain rating scale were used as outcome measuring tools Statistical analysis: The collected data was analyzed by using SPSS version 25 Results: There was a large improvement in pain intensity and improvement in functional limitation in both groups. However, group B showed that there was a more substantial improvement in pain and functional disability Conclusion: It was concluded that core stability based on Swiss ball exercises was more effective than conventional physiotherapy treatment in improving pain and function in patients of nonspecific low backache Key Words: Core Stability, Swiss Ball Exercises, Physical Therapy, Electrotherapy and Backache.
Sickle Cell Disease and Β Globin Gene Haplotypes Among Selected Sudanese Population in North Darfur State
Authors: Khalid Adam Nassreldeen , A. Maki , Ahmed Nahla , Abdurrahman Mohammed , Ahmed Mohammed , Ahmed Ibrahim , Hajissa Khalid
Published: November 2021

Aim: To identify β globin gene haplotypes and their frequencies in patients with SCD in North Darfur state, western Sudan Methods: This is a cross-sectional prospective community-based study that was carried out between December 2017 and August 2018. The study took place in the North Darfur state which is located in western Sudan. The study included 666 individuals (369 females and 297 males). Participants were screened for haemoglobinopathies using haemoglobin electrophoresis, while β globin haplotypes analysis for patients with SCD was carried out using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: Among the 666 participants, 579 (86.94%) had normal hemoglobin (AA), while 70 (10.51%), 13 (1.95%), and 4 (0.6%) had AS, SS, and AD respectively. Cameroon haplotype was found in 42.3% of the study group. Benin was 26.9%, Bantu was 23.1% and Senegal was 7.7%. Conclusion: The Cameron haplotype was found to be most prominent in Sudanese patients, thereby confirming the findings of previous studies in the country. Keywords: sickle cell disease; anemia; β-globin; haplotype; North Darfur; Sudan
Awareness Regarding Dental Charting and Dental Records in Human Identification Amongst Dental Practitioners: A Questionnaire Survey
Authors: Sulaima Areej , Khalid Abu , Alzahrani Mohammad
Published: November 2021

Forensic odontology plays a significant role in victim identification among the disasters of multiple fatalities or various murders or burns. It requires adequate teeth remains after the accident and dental records availability to succeed. Purpose: To evaluate the Awareness level of the role of dental charting and dental records in human identification amongst Saudi dental practitioners. Study Design: Descriptive Cross sectional study. Methodology: Present study enrolled 200 participants involving both genders. A self-administered questionnaire related to role of charting dental anomalies in human identification was uploaded online. Informed written consent was taken. Unwilling participants were excluded. Tatistical Analysis: The responses were carried out using the “pivot tables” option in Microsoft Excel (2016). Results: A total of 200 participants completed the survey male participants 74 (37%) were less than female participants 126 (63%). Almost 70% of respondents think that maintaining dental records/files can be forensically or medico-legally important. Low of knowledge was evident in different aspects of forensic dentistry.54%think teeth can be used as a primary source of identification of an individual (like DNA or fingerprints) while 46% considered it not. Conclusion: This study concluded that there was poor awareness among the dental practitioners and the poor of awareness can lead to improper human identification. Key Words: Forensic Odontology, Awearness, Attitude and Dental Practices.
Asperugo Procumbens: a Review of Botany, Traditional Uses, Phytochemistry and Pharmacology
Authors: Łazarski Grzegorz
Published: November 2021

Asperugo procumbens is a medicinal plant widely distributed in the world, which is commonly used in the traditional medicine of the Middle East, while currently overlooked in European pharmacopoeias. The aim of the study is to present a comprehensive overview of A. procumbens in botany, traditional medicine, phytochemistry and pharmacology according to the up-to-date data. Scientific literature on the species was collected based on publicly available databases such as: PubMed, Web of Science, Scopus, Google, Google Scholar as well as monographs and PhD theses. In traditional medicine the aerial part of A. procumbens is used for treatment of skin infections, herpes, liver and respiratory tract diseases, to strengthen the heart and the nervous system, and others. Contemporary studies on the pharmacological activity of A. procumbens revealed that it exhibits a wide range of pharmacological properties, including antioxidant, antidepressant, sedative-hypnotic, antibacterial, as well as chemopreventive and antihypertensive properties. Despite many proven medicinal properties, the species does not have a developed phytochemical profile and its chemical composition is very poorly understood. The species is known to contain tannins, flavonoids and phenolics. Only the content of fatty acids is recognised in detail. The species is a good source of omega-3 fatty acids – stearidonic acid (SDA), α-linolenic acid (ALA), and omega-6 fatty acid – γ-linolenic acid (GLA). This article, based on the available literature, highlights the traditional uses, phytochemistry and pharmacological properties of A. procumbens, which may provide a foundation for further pharmacological study as well as clinical application of the species. Keywords: Asperugo procumbens, German madwort, Boraginaceae, traditional uses
The Performance of the Cold Laser Therapy (GaAlAs-980nm)
Authors: Timimi Zahra Al-
Published: November 2021

Cold laser therapy has been largely utilized to enhance wound healing caused by several bio stimulatory characteristics conferred via laser rays obviously capable towards stimulate the restoration of flexible tissues wounds. Notwithstanding, the performance of pro-inflammatory interleukins has not been investigated yet. Interleukin-1 beta (IL-1β) represents an individual of largely imperative proinflammatory cytokines, which could be concerned in wounds therapeutic. The target of this work was to investigate the influence of a 980nm laser on the IL-1β expression and its secretion in wound healing in laboratory mice. Wounds with a standard-sized of 2cm have been carried out on the face of forty-laboratory mice. Animals have been divided into two groups; half of them undergo cold laser treatment at 980 nm, continuous illuminations, output power 5 W, beam spot area at the target had 0.7 cm2, and an energy density had 643 J/cm2 delivered without delay after wounds procedure. Furthermore, the other half of the animals had been set up as a control group. Next, the animals have been divided into four groups interconnected to the healing time intervals. A repairing operation area has been uprooting and further stained by the immunohistochemistry method towards identifying the appearance of (IL-1β). Cold laser therapy has proficient to amplify the appearance of (IL-1β) near the beginning of healing stages plus boosting epithelialization remodeling procedure within one to two weeks of healing time. Cold laser therapy tested in this work resulted in enlarged expressions of (IL-1β) in the laser treatment group considerably next to one week of healing time, which has an effect on wound healing. Keywords: Laser, wounds, therapy, photobiomodulation, healing, interleukins
Brief Motivational Interviewing Counseling to Improve Oral Hygiene Behavior Among Adolescent
Authors: . Ulliana , Santoso Bedjo , Utami Ulfah , Nurwanti Widi , Nurrochman Aditya
Published: November 2021

Aim: To analyze the effect of the brief motivational interviewing counselling approach on the knowledge, attitudes and tooth brushing practice of adolescents. Method: This research is a quasi-experiment with a pre-test and post-test design with a control group design. The research sample was 80 adolescents aged 12 and 13 years. Respondents were divided into two groups, namely 40 intervention and control groups based on inclusion criteria. The intervention group was given the MI approach, and the control group was assigned conventional dental health education. The MI group also received follow-up over the phone. Both groups filled out knowledge and attitude questionnaires before being given treatment. Plaque index and tooth brushing practice examinations were performed at baseline and four weeks after intervention. Results: The results showed an increase in the average score of oral health knowledge, attitude, tooth brushing practice in all groups. The plaque index showed a decrease in the average score in all groups. The test of both groups showed that brief MI counseling was more effective than conventional dental health education, oral health knowledge(p=<0.001), attitude((p=<0.001), tooth brushing practice( p = 0.001), plaque index (p = 0.011). Follow-up MI by telephone in adolescents is beneficial in the research during the covid-19 pandemic as a promotive and preventive effort to improve dental health behaviour. The MI method by telephone is very interesting for adolescents, easily accessible and time-efficient. Conclusion : The MI counselling brief intervention can change dental and oral health behaviour through increasing knowledge, attitudes, tooth brushing practices and reducing the dental and oral hygiene index scores of adolescents. MI interventions need to be combined with other interventions to get more effective results for research sustainability. Keywords: Motivational Interviewing, Oral Hygiene Behaviour, Adolescent
Mean Platelet Volume in Patients of Psoriasis in a Tertiary Care Hospital
Authors: Muzaffar Khan Bushra , Yaqoob Nida , Ahmed Najia , Anwar Ayesha , Tahir Moizza , Sadiq Sakina
Published: November 2021

Objective: To determine mean platelet volume in patients of psoriasis Study Design: Cross sectional study Place and duration of study: Dermatology Department, Pak Emirates Military Hospital Rawalpindi from August 2017 to January 2018. Methodology: Approval from the hospital ethical review committee was taken and a total of 100 patients were enrolled by non-probability consecutive sampling. After an informed written consent, name, gender, age, hospital record number, and phone number of each individual were noted. At the time of enrollment, all the individuals were subjected to complete blood count, bleeding time, fasting blood sugar, fasting lipid profile, renal and liver function tests. Patients with abnormal parameters were excluded from the study. A two ml venous blood sample was drawn from each patient and sent in CP bottle to the laboratory of Armed Forces Institute of Pathology for blood complete analysis by hematology analyzer machine. Data analysis was done using SPSS version 22. Results: In this study mean age was 40 ± 10.40 years. 54% patients were male and 46% patients were female. Mean platelet volume in patients presenting with psoriasis was 9.10fL with SD ± 2.12. Conclusion: Our study concludes that the mean platelet volume in patients presenting with psoriasis was 9.10fL with SD ± 2.12 which is in the normal range. Therefore, mean platelet volume is not affected by psoriasis. Key words: Mean platelet volume, psoriasis, severity, cross-sectional study
The Prevalence of Hepatitis D Virus in Reactive HBsAg Blood Donors at Department of Pathology, LUMHS Jamshoro
Authors: Akbar Sadia , Mumtaz Nazia , Fatema Sana , Ujjan Ikram Din , Aamir Kiran , Ramzan Aamir
Published: November 2021

Background: The hepatitis delta virus (HDV) is a defective hepatotropic virus that only affects patients infected with the hepatitis B virus (HBV). Infection with the hepatitis delta virus can cause acute hepatitis, including the fulminant presentation or spontaneously resolving infection and chronic infection Aim: The present study's aim was to determine the prevalence of the Hepatitis D virus in reactive HBsAg blood donors at Diagnostic and Research Lab Hyderabad. Materials and Methods: This cross-sectional study was conducted on 434 blood donors at the Pathology department (Diagnostic and Research Laboratory) Civil Hospital, Hyderabad from January 2017 to December 2017. All the healthy individuals who visited at Diagnostic and Research Laboratory of Civil Hospital, LUMHS Hyderabad as blood donors with specific age groups of either gender were included in this study. All the individuals underwent Hepatitis screening. All of those cases that were noted with positive HBV further underwent HDV screening test. All the data was recorded in the proforma for the purposed of analysis. SPSS version 20 was used for data analysis. Results: Of the total 434 blood donors, 420 (96.8%) were male and 14 (3.2%) were female. The overall mean age was 31.65±4.67 years with an age range of 18 to 60 years. Out of 434, the incidence of positive delta virus was 62 (14.3%) while the remaining 372 (85.7%) were negative delta hepatitis blood donors. The prevalence of delta hepatitis blood donors with respect to age distribution were as follows; 18-30 years had 208 (48%), 31-40 years had 188 (27%), 41-50 years 69 (16%), and 51-60 years 39 (9%). Of the total 62 positive delta hepatitis, the prevalence of males and females was 98.4% and 1.6% respectively. All the donor’s blood group was divided into +O, +B, +A, +AB, -O, -A, and –B with their respective prevalence was 48.6%, 22.6%. 11.5%, 8.8%, 2.5%, 3.5%, and 2.5% whereas their frequency in positive tested delta hepatitis was 36 (58.1%), 7 (11.3%), 10 (16.1%), 6 (9.7%), 1 (1.6%), 2 (3.2%), and 0 (0%) respectively. Conclusion: It is concluded that the prevalence of HDV is 14.3% in Hepatitis B reactive healthy donors. This is a higher prevalence as compared to previously published studies. No such adequate recent data is available at the local level. More research is needed on this event, to provide adequate knowledge, which will be helpful to clinical and laboratory investigators, and physicians to reduce the burden of liver disease caused by HBV and HDV co-infection. Keywords: Hepatitis delta virus; HBsAg reactivity; Blood donors;
An Insight into the Knowledge, Attitude and Practice towards Blood Donation among the Residents of Hyderabad Sindh
Authors: Mumtaz Nazia , Akbar Sadia , Fatema Sana , Ujjan Ikram Din , Aamir Kiran , Ramzan Aamir
Published: November 2021

Background and Aim: In developing countries with a high prevalence of bleeding disorders, safe and adequate blood supply has persisted as a major challenge. Blood transfusion and donation in Pakistan are based on replacement donor’s primitive practice whereas voluntary donors worldwide replaced replacement donors. The present study objective was to evaluate the blood donor’s knowledge, attitude, and practice towards blood donation to measure their understanding of blood donation. Materials and Methods: This descriptive cross-sectional study was conducted from November 2020 till June 2021 at the Diagnostic and Research Laboratory, LUMHS Hyderabad. A pre-tested, self-administered survey form was utilized to investigate a total of 350 respondents. Out of the total, 160 were healthcare workers, 90 were medical students, and 100 were general public. Data was analyzed using SPSS version 20. Results: Of the total 350 respondents, the prevalence of blood donors and non-donors were 114 (32.6%) and 236 (67.4%) respectively. Out of 114 blood donors, 87 (76.3%) were male and 27 (23.7%) were female donors. The overall mean age was 37±6.45 years. The prevalence of knowledge, attitude, and practice among health workers was 56%, 64%, and 41% whereas students had 77%, 56%, and 22%, and the general public had 19%, 48%, and 78% respectively. The main reasons for not donating blood were fear of needles or sight of blood, weight loss/gain, lead to anemia, decreased immunity, and no one asked to donate with respective prevalence 11%, 17%, 39%, 21%, and 41%. About 56% of donors donated blood for the first time followed by 37% more than once. Conclusion: The knowledge, attitude, and practice survey concluded that a rational design, voluntary blood donation campaign, targeted strategies, and awareness program could be planned to utilize and increase blood donors on a community level. Keywords: Blood donation, Donors, Knowledge, Attitude, Practice
Visual detection of microbial community during three bacteria mixed fermentation through hyperspectral imaging technology
Authors: Li Yanxiao , Hu Xuetao , Shi Jiyong , Qiu Baijing , Xiao Jianbo
Published: November 2021

Hyperspectral imaging technology with chemometrics was used for identifying and counting each species in microbial community during mixed fermentation. Hyperspectral images of microbial community of Enterobacter sp, Acetobacter pasteurianus, and Lactobacillus paracasei colonies were obtained and the spectra of strain colonies were extracted. Identification models were developed using linear discriminant analysis (LDA) and least‐squares support vector machine (LS‐SVM) by using 23 variables selected by genetic algorithm. The optimal LS‐SVM model with an identification rate of 96.67 % was used to identify colonies and prepare colony distribution maps in color for strains counting. The counting results by hyperspectral imaging technology agreed with that of the manual counting method with an average relative error of 3.70 %. The developed counting method has been successfully used to identify and count the specific strain from the mixed strains simultaneously. The hyperspectral imaging technology has a great potential to monitor changes in the microbial community structure.