bluuebunny/crossref_metadata_2025 huggingface dataset:
ATUALIDADE DE PAULO FREIRE
Authors: Andreola Balduíno Antonio , Ghiggi Gomercindo
Published: October 2020

A atualidade de Paulo Freire pode ser avaliada a partir de diferentes indicadores, entre eles, o das instituições, no Brasil e no mundo, dos grupos e movimentos que promovem pesquisas, ações e projetos, nos campos da educação e desenvolvimento humano em geral. No Rio Grande do Sul, a XV sessão anual do Fórum de Estudos: Leituras de Paulo Freire, realizada em 2013, teve mais de duzentos trabalhos apresentados. O VIII Colóquio Internacional do Centro Paulo Freire de Estudos e Pesquisas, de Recife, teve participação ainda mais ampla. O Instituto Paulo Freire de São Paulo é outro exemplo da atualidade do autor. Pedagogia do oprimido tem hoje 50 edições e está traduzido em mais de 20 línguas, Educação como prática da liberdade está na 34ª edição e Pedagogia da autonomia, na 43ª. Pedagogia do oprimido é mais que um livro, é um projeto a serviço de um mundo mais solidário e foi recriado de muitas maneiras, no mundo inteiro, nos campos da educação, da ética, da ecologia, da saúde, da cultura e da política.
AGGREGATED FINANCIAL CONTRIBUTIONS OF SOME ACTIVITY SECTORS ON NIGERIA’S ECONOMIC GROWTH USING ARDL MODEL
Authors: Amaefula C. G  , Umezurike C. M
Published: October 2020

The paper examines the aggregated financial contributions of industrial and services sector output on the economic growth of Nigeria using ARDL model. The data sets on gross domestic product (GDP) and industrial and services sector output (measured in billions of naira) cover the period of 1981 to 2019. The ADF unit root test was used to test the order of integration of the variables under study. Applying Generalized Linear Model (Newton-Raphson) method of estimation, the results showed that both the industrial sector (IND) and services sector (SERV) contributed positively to GDP growth both at the short-run and long-run, significant under 5% level and the system is adjusting towards long-run equilibrium at the speed of approximately 102%. Therefore, the government should put more effort in industrial and services sector reforms so as to make these sectors more proactive at improving economic growth in Nigeria.
KEYWORDS: Industry, services sector, economic growth, ARDL
CHRONIC HEART FAILURE COURSE PROGNOSIS DEPENDING ON BODY WEIGHT AND ENDOGENOUS INTOXICATION SYNDROME
Authors: Kondratyuk Marta O. , Sorokopud Olena O. , Strіl’chuk Larysa M. , Zhakun Іryna B. , Slaba Oksana R. , Besh Olesya M. , Radchenko Olena M. , Leshchuk Yaryna L.
Published: October 2020

Introduction: Over the years, heart failure remains one of the most common and prognostically unfavorable conditions.
The aim of our study was to determine the frequency of complications in patients with CHF depending on the body weight and intoxication syndrome of varying degrees of severity.
Materials and methods: A complete clinical examination was performed in 58 patients (41 (70.6%) men and 17 (29.4%) women) with CHF. In addition to the standard examination in
accordance with the protocol, the level of endogenous intoxication was determined by the level of medium-weight molecules (MWM254) and leptin. The patients were randomized into 4 groups
depending on their body mass index and the degree of endogenous intoxication. Statistical processing of the results was carried out using the methods of variation statistics “Statistica 6.0”.
Results: It was revealed that the worst survival rate is observed in patients with normal body mass against the background of the expressed endogenous intoxication syndrome, the best survival rate is observed provided that there are a normal body mass and endogenous intoxication of a minimum degree. An inverse correlation between the body mass index and the endogenous intoxication indicator (blood MWM) was detected. Patients with CHF should have their leptin level evaluated. An increase in its level was associated with arterial hypertension, an increase in blood glucose levels and lipid metabolism disorders.
Conclusions: Increased level of blood MWM worsens the forecast of CHF. The unfavorable outcome was observed in patients with the combination of hypoleptinemia with severe endogenous intoxication.
COMPARATIVE ANALYSIS OF THE METHODS OF ANESTHETIC MAINTENANCE IN PATIENTS WITH DIABETES WITH THE SYNDROME OF DIABETIC FOOT REQUIRING OPERATIVE INTERVENTION
Authors: Filimonov Roman V. , Filimonova Inna V. , Shapoval Serghey D. , Kobeliatskyi Yury Yu.
Published: October 2020

Introduction: In the present article we draw a comparison between such types of regional anesthesia (RA) as unilateral spinal anesthesia (USA), traditional spinal anesthesia
(SA) and block anesthesia of peripheral nerve trunk (block anesthesia of sciatic nerve (BASN) on the side of operative intervention) during surgical treatment of patients with
the syndrome of diabetic foot.
The aim of the article is to compare effectiveness, reliability and safety of such methods of RA as unilateral and traditional spinal anesthesia, as well as block anesthesia of
sciatic nerve on the side of operative intervention.
Materials and methods: 96 patients with the syndrome of diabetic foot, who received treatment in the department of purulent surgery, were examined. All patients underwent
operative interventions of varying degrees of complexity depending on the nature and seriousness of damage degree of extremities, in terms of RA types under investigation.
Effectiveness of regional block anesthesia, the time when anesthesia takes effect, duration and deepness were evaluated.
Results: It should be noted that USA, as a variant of pain management during operations of foot, provides the most adequate level of surgical pain management in comparison
with the other types of anesthesia. During block anesthesia of sciatic nerve more than half of patients are not provided with 100% surgical analgesia, which can lead to additional
medicamentous analgosedation. According to the results obtained, pain sensitivity in patients after BASN is reliably higher than in patients after USA and SA in all stages of the study.
Conclusions: RA is the main method of choice during operations on foot in comparison with the methods of general anesthesia. Unilateral spinal anesthesia is carried out with
the use of smaller amount of anesthetic than traditional spinal anesthesia and block anesthesia of peripheral nerve trunk, which significantly reduces sympathectomy area and
leads to the stable hemodynamic during the peri-operative period.
CHANGES OF PSYCHO-EMOTIONAL STATE IN THE INFERTILE PREGNANT FEMALES DUE TO THE ANAMNESIS AND IVF
Authors: Likhachov Volodymyr K. , Shymanska Yanina V. , Savelieva Yulia S. , Vashchenko Viktoriya L. , Dobrovolska Ludmyla М.
Published: October 2020

Introduction: During pregnancy in the body of a healthy woman there are physiological and psychological changes that contribute to the bearing a child and prepare the female for future labour and motherhood. In women who experience failure at the stage of fertilization or during pregnancy, as a result of prolonged negative emotional states, psycho-emotional stress develops. The aim of the research was to study the psycho-emotional state of women with infertility in history, whose pregnancy resulted from extracorporal fertilization (IVF), and to develop methods for reducing their anxiety. Materials and methods: At the first stage, the initial psycho-emotional state of 60 women in the second trimester, whose pregnancy resulted from IVF (Group I), was studied; the control group consisted of 20 healthy women with a physiological course of pregnancy (Group II). At the second stage, 10 art therapy exercises with a requestioning of pregnant women from Group I were conducted for improving their psycho-emotional state. Results: Women of Group I had a high level of both situational anxiety (SA) and the personal one (PA). The prevalent type of the psychological component of gestational dominant was anxiety and euphoric types (58.3%). In one third of women with burdened gynecological history examined mild or masked depression was diagnosed. 43 pregnant women from Group I used a method of psychocorrection – art therapy, which included colouring “antistress” pictures of perinatal topic, making flowers from paper and creating a collage of dreams. Conclusions: After the art therapy course, a high level of SA (from 46.5% to 7.0%) and OA (from 48.8% to 32.6%) decreased, the index of the optimal type of the psychological component of gestational dominant increased from 25.6% to 53.5%. The number of women without depression increased from 62.8% to 93%.
IMPROVEMENT OF THE METHODS OF SURGICAL TREATMENT IN PATIENTS WITH INFRALENAL ANEURYSM OF THE ABDOMINAL AORTA
Authors: Liksunov Oleksandr V. , Prysyazhna Nataliya R. , Ratushnyuk Andriy V. , Nikulnikov Pavlo I.
Published: October 2020

Introduction: Nowadays, there is an increase number of patients with abdominal aortic aneurysm. The disease has a constantly progressive nature, the result of which is the rupture
of aneurysms and a high mortality rate. However, the technologies of operations are still controversial. Unidentified factors of complications and mortality remain with this pathology.
The aim: to determine the risk factors of complications in patients with the aneurysm of the abdominal aorta
Materials and methods: Analyze data of the examination and treatment results of 117 patients with aneurysm of the abdominal aorta. 58 patients were examined and treated
according to advanced methods in a treatment group. The control group consisted of 59 patients who were examined and operated according to standard, generally - accepted methods.
Results: According to our observations after the planned operations, the most common were cardiac complications. Analyzing the frequency of complications depending on
the type of surgical intervention, we have not established statistically significant differences. More significant volume of blood loss was observed when performing combined
operations and aorto-bifem bypass in comparison with aortic bypass and aorto-biiliac bypass.
Conclusions: Combined operations result in a significantly higher blood loss compared to linear prosthetics.The level of intraoperative blood loss in patients with «large»
aneurysms is significantly higher than in patients with «small» and «average» aneurysms.
COMORBIDITY SEVERITY INDEX AS A NEW TOOL FOR ASSESSMENT OF CO-EXISTING DISEASES IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AT THE CARBOHYDRATE METABOLISM DISORDER BACKGROUND AND CONCOMITANT SUBCLINICAL HYPOTHYROIDISM
Authors: Feysa Snizhana V. , Chopei Ivan V.
Published: October 2020

Introduction: Non-alcoholic fatty liver disease (NAFLD) is the most common disease which is characterized by comorbidity. However, no comorbidity index for its assessment
has been described yet.
The aim of this study was to develop a new index for evaluation of comorbidity in patients with NAFLD.
Materials and methods: 226 patients with NAFLD and associated carbohydrate metabolism disorders were examined. Besides, 60 persons with subclinical hypothyroidism,
30 patients with type 2 diabetes mellitus (T2-DM) and 30 NAFLD patients were examined. 30 healthy persons formed the control group. Clinical diagnoses were based on the
laboratory tests and liver sonography. A new index of comorbidity has been used. Calculation of comorbidity severity index (ComSI) includes the possible presence of NAFLD,
thyroid disorders, abdominal obesity, dyslipidemia, anemia, chronic complications of T2-DM, aggravated anamnesis.
Results: The contradiction in the calculation of the well-known comorbidity indices values (CIRS – Cumulative illness rating scale, CCI – Charlson’s comorbidity index,
Kaplan-Feinstein index) was shown. So, their limited suitability for using in patients with carbohydrate metabolism disorders who have NAFLD was detected. According
to our results an increasing of patients’ age is associated with the increasing of concomitant diseases number and with deteriorating of the patients’ general condition,
which is reflected in an increasing of the ComSI value. The increasing of concomitant diseases number is associated not only with the higher ComSI, but also with the
number of persons with a severe comorbidity according the ComSI value. Instead, the persons without comorbidity (groups 6, 7, 8) were marked as the patients with mild
or moderate disease according the ComSI.
Conclusions:The new ComSI index can be used to evaluate the severity of comorbidity in patients with NAFLD.
INTEGRAL SCORING SCALE AS A BASIS FOR AN OBJECTIVE
ASSESSMENT OF THE STATE OF PATIENTS WITH CHRONIC
TONSILLITIS AND THE EFFECTIVENESS OF THEIR TREATMENT
Authors: Bredun Oleksandr , Melnikov Oleg , Kononov Oleksandr
Published: October 2020

Introduction: Currently, the methods of integrated assessment of patient’s condition based on scoring of separate multidirectional changes in subjective clinical and objective
laboratory parameters are used in medical science more and more often.
The aim: Based on the identified differences in clinical manifestations and immunological indicators of patients of different age with chronic tonsillitis and patients with no
signs of ENT pathology, to develop an integral scoring scale as a basis for an objective assessment of the state of patients with CT and the effectiveness of their treatment.
Materials and methods: The clinical signs and immunological factors were evaluated. Patient’s general information, such as age, the presence of allergies, was also taken into
account. Based on the analysis of the data array, a scoring system for assessing the clinical and immunological state of patients was proposed.
Results: The abnormalities in clinical and immunological assessment in adult population with no signs of ENT pathology (control group) are 2.75 times higher than in healthy
children, while in case of chronic tonsillitis the differences between children and adults in terms of integral abnormalities are 1.66 (p<0.05).
Conclusions: Integral scoring assessment of clinical and immunological tests makes it possible to provide more objective evaluation of the state of lymphoid tissue of
tonsils and the immunity in patients with chronic tonsillitis, which may become an objective basis for choosing patient management strategy, as well as for estimating
treatment efficacy.
EXPERIENCE IN TREATMENT OF PATIENTS WITH ESOPHAGEAL ACHALASIA
Authors: Shaprynskyi Volodymyr O. , Kanikovskyi Oleg Y. , Shaprynskyi Yevhen V. , Karyi Yaroslav V.
Published: October 2020

Introduction: Esophageal achalasia is a neuromuscular disease, which is characterized by persistent impaired reflex opening of esophageal sphincter. Disease incidence is
0.6-2.0 per 100 000 population with no tendency to decrease.
The aim of the study was to improve the results of treatment in patients with achalasia of cardia by differentiated approach in the choice of therapy method.
Materials and methods:148 patients with esophageal achalasia aged 18 - 67 were studied between 2003 and 2018. The following degrees of the disease were determined
(by Petrovskyi’s classification): first – in 8, second – in 59, third – in 70, fourth – in 11 patients. Drug therapy was administered in achalasia of first degree, and cardiodilatation
courses - in second and third degree of the disease. Indications for surgical treatment were: impossibility to perform cardiodilatation, S-shaped esophageal deformation (stage
IV), complications associated with cardiodilatation, achalasia combined with other surgical pathology, recurrence of disease.
Review: Cardiodilatation therapy resulted in sustained clinical effect in stages I and II of the disease. In case of unsatisfactory results of cardiodilatation patients
underwent elective operations. 18 patients underwent Heller-Dor plastic surgery, 4 – Heller-Petrovskiy operation, 1 – Besley plastic repair, 2 – Nissen fundoplication.
In early postoperative period no failure or perforation of the esophagus occurred. The following complications developed: seroma – in 3 patients, postoperative wound
infection – in 1 case. In one patient (4%) the recurrence of disease was due to scar deformation of esophagogastric junction after Heller-Petrovskiy operation on the cardia.
Conclusions: Cardiodilatation is an effective method of conservative therapy in stages I and II of the disease, while in stages III and IV it is warranted as preoperative preparation
measure. We think Heller-Dor operation to be the best method of plastic repair in esophageal achalasia.
THE WAY THE HEALTH CARE SYSTEM IN UKRAINE LOOKS LIKE: INTERNATIONAL PRACTICES WITHIN NATIONAL REALITIES
Authors: Lohvynenko Borys O. , Myroniuk Roman V. , Svitlychnyy Olexander P. , Prokopenko Aleksey Y. , Kalenichenko Lidija I.
Published: October 2020

Introduction: Nowadays there is the transformation of the national health care system in Ukraine, the ultimate goal of which is to create a modern, competitive model of medical care of citizens on the basis of forming packages of free medical services. However, the model adopted by Ukraine is in contradiction with national legislation in part of free medical aid guaranteed by the Art. 49 of the Constitution of Ukraine, and fragmentary considers positive international practices. The aim of the paper is to determine the mistakes of the reform of the Ukrainian health care system and to reveal the positive international practices of the organization of health care systems that can be implemented in Ukraine. Materials and methods: National and international legislation, official web resources of the executive authorities of Ukraine, statistics of the World Health Organization, materials of journalistic and scientific periodicals are the materials for the research of the health care system in Ukraine in comparison with international practices. Research methods are cross-sectoral, complex statistical, comparative, generalization, analysis and synthesis. In order to obtain the results, the authors have conducted a critical analysis of the current norms of the national Ukrainian legislation in the health care sector. Review: The authors of the article have studied the main disadvantages of the national health care system in accordance with the concept of reforming the medical sector. Positive international practices that can be implemented into Ukrainian system for the real improvement of medical human rights in Ukraine have been revealed. Conclusions: It has been proved that the ongoing reform of the health care system in Ukraine needs to be reviewed and optimized. It has been offered to consolidate a perspective model of the Ukrainian health care system, its principles and guarantees of immunity at the legislative level.
LEGAL ENFORCEMENT AND DEVELOPMENT DIRECTIONS OF HEALTH LAW IN UKRAINE
Authors: Vilchyk Tetyana В. , Krainyk Нrіhorіі S. , Shandula Oleksandr O.
Published: October 2020

Introduction: The development of medical law should take place systematically based on scientific basis and guided by international experience. The article describes the
tendencies and prospects of the medical law development of Ukraine in the context of globalization and European integration processes.
The aim of this work is to investigate the problems of legal enforcement and directions of the medical law development in Ukraine
Materials and methods: We analyzed national and international acts that regulate community rights for medical care, protection of patient rights, which were studied using
content analysis and analytical experience, as well as generalization of court practice and statistical data.
Review and conclusions: Violation of patient rights is a socially harmful act, impunity of which also affects social security. The quality control mechanism of medical care
should be permanent and aimed at improving this quality. It is necessary to create a National Quality Control Agency that would be independent, not subordinate to the Ministry
of Healthcare of Ukraine, with professional experts with experience in this direction. The problem of legal protection of patient and doctor rights, as well as provision of legal
support to medical institutions and the creation of a regulatory framework to reform the health care system is relevant. It is necessary to create a register of medical lawyers.
Creating a system for reporting and monitoring medical errors should be one of the priorities of health care reform in Ukraine.
THE ROLE OF INTERLEUKINS AND THEIR INHIBITORS IN THE DEVELOPMENT OF AUTOIMMUNE UVEITIS
Authors: Kuryltsiv Nadiya B. , Halei Kateryna M.
Published: October 2020

Introduction: Autoimmune uveitis (AU) is an inflammation of the uvea due to an autoimmune reaction to self-antigens. There are no standardized treatment protocols for
AU. A new class of drugs called biologics, that target the various mediators of the inflammation cascade, may potentially provide more effective and less toxic corticosteroids
treatment of AU.
The aim: The aim of this review was to make the evaluatation of the interleukins influence on intraocular inflammation in available literature and summarize the expediency
of using anti-interleukins agent in case of AU.
Material and methods: This article is a review and summary of the up-to-date results of pivotal experimental and clinical trials targeting the Interleukins (IL), including IL-6,
IL-10, IL-17, IL-22, IL-23, and tumor necrosis factor alpha (TNF-α). Also reviews focus on the potential use of anti-interleukin therapy for the treatment of autoimmune diseases (AD).
Conclusions: AU is an inflammation of the uvea due to an autoimmune reaction to self-antigens. The most important IL in the pathogenesis of AU are IL-6, IL-10, IL-17, IL-22,
IL-23 and TNF-α. Anti-interleukin therapy is partially described. Future randomized controlled trials are urgently needed to be conduct.
EFFICIENCY OF USING THE DIODE LASER IN THE TREATMENT OF PERIODONTAL INFLAMMATORY DISEASES
Authors: Gadzhula Nataliia G. , Shinkaruk-Dykovytska Mariia M. , Cherepakha Olena L. , Goray Maryna A. , Horlenko Irina  M.
Published: October 2020

The aim: To study clinical efficiency of using the diode laser in the treatment of chronic catarrhal and
hypertrophic gingivitis.
Materials and methods: Treatment of 32 patients with chronic catarrhal gingivitis and 30 patients
with hypertrophic gingivitis by basic therapy according to the protocols of dental care was carried
out. The patients of the main groups were additionally subjected to laser irradiation of the affected
areas of the gums with a diode laser.
Results: The use of laser therapy in the treatment of chronic catarrhal gingivitis contributed to the
pain relief, reducing of bleeding and edema of the gums in 68.8% of patients on the 3rd day of
observation. On the 7th day, 93.8% of the examined patients had no inflammation in periodontal
tissues. During treatment of hypertrophic gingivitis, anti-inflammatory and decongestant effects,
improvements in the aesthetic appearance of the gums were revealed in 33.3% patients on the 3rd
day of the examination; absence of inflammation, gingival bleeding and gum hypertrophy was
diagnosed in 53.3% on the 7th day and in 80.0% patients on 14th day of follow-up. In the control
group, similar changes were revealed only in 68.8% patients with catarrhal gingivitis and in 46.7%
patients with hypertrophic gingivitis after complete course of drug treatment in 14 days of
observation.
Conclusions: The use of a diode laser in patients with chronic gingivitis has provided a reduction in
the term required for the complete elimination of the inflammatory process and suspended its further progression.
THE ROLE OF CHOLINERGIC INSUFFICIENCY IN COGNITIVE IMPAIRMENT AMONG PATIENTS WITH CHRONIC CEREBRAL ISCHEMIA
Authors: Chernii Tatiana V.
Published: October 2020

The aim: A correction of cholinergic insufficiency for the treatment of cognitive impairment in chronic brain ischemia.
Materials and methods: In the period 2014 – 2017, 88 people aged 40 to 68 years were comprehensively examined in dynamics. Patients were divided into three groups, statistically comparable to the main disease – CCI 2 degrees, gender and age. In addition to the protocol, patients with discirculatory encephalopathy of all the investigated groups received a complex of drugs aimed at correcting neurotransmitter metabolism.
Results: The statistically significant manifestations of the recovery of cognitive function (according to the MMSE scale) after the application of the developed complex therapy were associated mainly with a decrease in impulsivity due to an increase in the level of attention. The statistically significant manifestations of a decrease in the level of anxietydepressive disorders (according to the DASS-21 scale) after the application of the developed complex therapy were associated mainly with a decrease in anxiety due to the restoration of neurohumoral balance.
Conclusions: The inclusion in the treatment protocol for CCI complex of drugs aimed at eliminating cholinergic deficiency, acetylcholinesterase inhibitors in combination with choline precursors, leads to the correction of cognitive impairment in chronic brain ischemia.
POSTPARTUM MASTITIS IN THE BREASTFEEDING WOMEN AND ANTIMICROBIAL RESISTANCE OF RESPONSIBLE PATHOGENS IN UKRAINE: RESULTS A MULTICENTER STUDY
Authors: Salmanov Aidyn G. , Savchenko Serhii E. , Chaika Kyrylo , Vitiuk Alla D. , Ruban Iana , Dyndar Olena A. , Zhelezov Dmytro , Vorobey Ludmila , Semeniuk Liudmula M. , Hetsko Natalia V. , Tsmur Olga V. , Suslikova Lidiya V. , Nykoniuk Tetiana R. , Shunko Yelizaveta Ye. , Beketova Halyna V. , Manzhula Lyudmila V. , Kurochka Valentyna V. , Abbasova Esmira R.
Published: October 2020

The aim: To obtain the prevalence of mastitis in the breastfeeding women and antimicrobial resistance of responsible pathogens in Ukraine.
Materials and methods: A retrospective multicenter cohort study was based on surveillance data for Postpartum Mastitis and included 18,427 breastfeeding women’s who gave birth in 11 regional hospitals of Ukraine.
Results: 22.6% breastfeeding women’s were found to have breast infections. Among these patients, 11.6% breast abscess and 88.4% mastitis were observed. Of the total cases breast infections, 74.8% were detected after hospital discharge. The rate of healthcare-associated mastitis was 8.6%. The predominant pathogens were: Staphylococcus aureus (23.6%), Escherichia coli (19.4%), Enterobacter spp. (11.9%), Staphylococcus epidermidis (10.7%), Klebsiella spp. (8.7%), Pseudomonas aeruginosa (4.8%), Enterococcus faecalis (4.8%), and Proteus mirabilis (4.6%). The overall proportion of methicillin-resistance was observed in 27.9% of S. aureus (MRSA) and 24.3% of S. epidermidis (MRSE). Of the total methicillin-resistance strains, 74.8% of MRSA and 82.1% of MRSE is community-acquired, were detected after hospital discharge. Vancomycin resistance was observed in 9.2% of isolated enterococci. Carbapenem resistance was identified in 7.3% of P.aeruginosa isolates. Resistance to third-generation cephalosporins was observed in 8.8% Klebsiella spp. and E.coli 9.1% isolates.
Conclusions: Mastitis in the breastfeeding women in Ukraine requires medical attention it is common, and a lot of cases are caused by pathogens resistant to antibiotics. Optimizing the management and empirical antimicrobial therapy may reduce the burden of mastitis, but prevention is the key element.
EXPERIMENTAL STUDIES OF THE EFFECT OF ELECTROSURGICAL AND STANDARD TECHNIQUES ON PANCREATIC RESTORATION
Authors: Valikhnovska Kateryna G. , Savytska Iryna M. , Nataliya Prysyazhna R. , Voitiv Yaroslav Y.
Published: October 2020

The aim: There have been investigated the specific features of pancreatic resection with the use of electrosurgical methods on experimental models of clinical operations. Pancreatic tissue regeneration at the surgical site have been studied when employing monopolar, bipolar, electric welding methods as compared with standard surgical technique. Materials and methods: The study was performed on 40 white laboratory rats. Pancreatic resection was conducted by standard surgical technique or by welding with electrocoagulation device “Patonmed EWD-300”, high-energy electrosurgical device in bipolar mode and in monopolar mode. The pancreatic tissue was examined immediately after the surgery and at 3, 7 and 21 days postoperatively. Results: In early terms following standard surgery there was seen more severe inflammation and the volume of newly formed connective tissue got increased faster than after the electrosurgical technique. Pancreatic ducts developed in newly formed tissue after the use of each type of electroresection, whereas that event was not observed following standard surgery. When using electrosurgery in monopolar mode, the area of coagulative necrosis was found to be less dense than after resection performed in bipolar mode. Conclusions: Based on the findings, we can conclude that each of the above types of electroresection reduces surgery time, lowers bleeding risks, contributes to formation of the more adequate sealing on the resection surface with no complications of the recovery process.
INDICATORS OF LEFT VENTRICLE HYPERTROPHY IN PATIENTS WITH ARTERIAL HYPERTENSION COMBINED WITH OBESITY AND THEIR INTERCONNECTION WITH POLYMORPHISM OF LYS198ASN GENЕ OF ENDOTHELIN-1
Authors: Smiianova Yuliia O. , Prystupa Liudmyla N. , Chernatska Olha M. , Smiianov Yurii V.
Published: October 2020

The aim of the study was to find dependence of left ventricular hypertrophy indexes to polymorphism of Les198Asn gene endothelin-1 and BMI.
Materials and methods: We took research in 160 patients with arterial hypertension, using ECG and polymerase chain reaction (PCR). Groups were divided additionally according to BMI (body mass index).
Results: It was found, that patients with obesity had their Left ventricular mass and hypertrophy left ventricular indexes higher, than in patients with normal and increased body weight. Carriers of Asn198Asn and Lys198Asn genotypes Left ventricular mass and hypertrophy left ventricular indexes are higher than in carriers of Lys198Lys genotype.
Conclusions: It was determined that in patients-carriers of Asn198Asn genotype, Left ventricular mass (LVMI) and hypertrophy left ventricular indexes (LVMMI) were higher compared to patients-carriers of Lys198Lys and Lys198Asn type, both in men and women. The dependence of LVMI and LVMMI are shown to be higher in patients with obesity than in people with normal and increased body mass.
HUMAN HEALTH AS A PHILOSOPHIC PHENOMENON AND AN IMPORTANT COMPONENT OF NATIONAL SECURITY AND STATE SOVEREIGNTY POTENTIAL
Authors: Radysh Yaroslav F. , Moiseyenko Raisa O. , Mykhalchuk Vasyl M.
Published: October 2020

The aim: Examination of the human health problem as a philosophical phenomenon and an important component of national security and potential of the state sovereignty.
Materials and methods: The authors have analyzed scientific data (7 references) using methods of systemic approach and systemic analysis.
Conclusions: The population health was always and is currently a state priority in civilized countries. Ukrainian researchers have no doubt the problem “Population health and state security and defense” needs the participation of not only medical specialists, but also of sociologists, economists, ecologists, politicians; this problem is a poly-disciplinary one. Reforms in the health care field of Ukraine are to solve an especially important and urgent task – strengthening of Ukrainian people health. The essence of concepts «national security» та «sovereignty of the state» being conditioned to a significant degree by the health state of our citizens leads to affirmation the steadfast state sovereignty to be a factor ensuring the stability and high level of national security.
It is currently of the greatest importance to take into consideration all the possible configurations of future having determined strategic priorities and preparing favorable conditions for steadfast development. Currently, such development is dependent on the level of community health and quality of state government.
TEMPORARY ACCESS TO DOCUMENTS CONTAINING MEDICAL CONFIDENTIALITY (CRIMINAL PROCEDURAL ASPECT)
Authors: Ablamskyi Serhii Ye. , Romaniuk Vitalii V. , Chycha Ruslan P. , Ablamska Viktoriia V.
Published: October 2020

The aim of the study: 1) to determine the features of temporary access to documents containing information that may be a medical confidentiality; 2) to identify legislative gaps regarding the regulation of the measure of criminal proceedings; 3) to formulate proposals for improvement of legislation in the part of the investigated issue.
Materials and methods: The legal basis for the protection of information that may be a medical confidentiality is provided. Legislative provisions have been identified and analyzed, which provide for particulars of access to documents containing information that may be a medical confidentiality. It is argued that the evidence collected in violation of the procedural order of the measure of criminal proceedings is inadmissible and therefore cannot be taken into account by the court in the future. Writing the article, the authors used both general and special methods of scientific knowledge, namely: formal-legal, formal-logical, comparative analysis and logical-normative. The complex application of these methods has made it possible to formulate science-based conclusions and proposals.
Conclusions: Exemption of documents containing information that may constitute medical confidentiality should be done exclusively by temporary access to them. In order to eliminate the legislative gaps of the investigated issue, it is proposed to amend the current legislation accordingly.
METHOD OF FORENSIC ASSESSMENT OF RISK FACTORS OF TREATMENT FAILURE OUTCOMES AS AN ELEMENT OF QUALITY MANAGEMENT OF MEDICAL CARE
Authors: Sokol Vyacheslav K. , Kolesnichenko Vira A. , Sokol Kostyantin M. , Smiianov Vladyslav A.
Published: October 2020

The aim: The aim of this research was to study causes of the development of adverse outcomes in isolated femоral diaphyseal fractures. Materials and methods: A retrospective analysis of the protocols of clinical and radiological examination of 21 patients was performed. Based on the initial expert assessment, these patients have not been established the severity of injuries due to the development of complications in the postoperative period. Conclusions: Patient-dependent, implant-dependent, and surgery-dependent causes that caused a violation of the stability of osteosynthesis (95.2%) were identified. This led to a secondary displacement of bone fragments (71.4%), delayed fracture consolidation (61.9%), the formation of pseudarthrosis (38.1%), the development of post-traumatic osteomyelitis (14,3), migration of screws from the osseous plate (47.6%), and the development of post-traumatic contracture of the knee joint (81.0%).
SUBACUTE ENTEROVIRUS-ASSOCIATED ENCEPHALITIS IN A YOUNG ADULT COINFECTED WITH BORRELIA BURGDORFERI
Authors: Dyachenko Pavel A. , Kurhanska Victoriia A. , Dyachenko Anatoly G. , Smiianova Olha I.
Published: October 2020

The aim: To pay attention of clinicians to sterile encephalitis in adults, which in fact may be caused by EVs.
Results: A young woman was admitted to our clinic because of 3-month-history of mild fever, left-sided soft facial paralysis, and generalized weakness. MR brain imaging in T2W, FLAIR, and T1W mode showed focal hyper intensive abnormalities in various parts of the left hemisphere. EV RNA was detected in the patient’s CSF on admission. IgM class antibodies to B.burgdorferi were present in the blood. Antibiotics and ribavirin have been administrated with a good effect.
Conclusion: This case shows that EV infection may cause brainstem encephalitis accompanied by severe neurological manifestations in adults.
Pengaruh Rasio Profitabilitas Terhadap Perubahan Laba
Authors: Bayu Pasupati
Published: October 2020

Penelitian ini bertujuan untuk melakukan pengujian lebih lanjut mengenai penggunaan Rasio Keuangan dalam memprediksi Perubahan Laba pada perusahaan yang terdaftar di Bursa Efek Indonesia pada Sektor 7-infrastruktur, utilitas dan transportasi dengan sub sektor jalan tol, pelabuhan, bandara dan sejenisnya (72) serta transportasi (74). Perubahan Laba diukur berdasarkan laba bersih sebelum pajak serta Rasio Keuangan menggunakan pengukuran Profitabilitas. Penelitian ini menggunakan pendekatan kuantitatif, sumber data penelitian ini meliputi data sekunder yaitu data yang diperoleh dari website Bursa Efek Indonesia (www.idx.co.id). Metode analisis data menggunakan analisis regresi linier sederhana dengan dilakukan analisis statisitik deskriptif dan uji asumsi klasik terlebih dahulu. Hasil penelitian tidak membuktikan pengaruh Rasio Profitabilitas dengan pengukuran Return on Equity terhadap Perubahan Laba (EBIT). Rendahnya nilai koefisien determinasi sebesar 3,9 persen menandakan bahwa banyak sekali faktor lainnya yang menentukan Perubahan Laba.
Prediksi Minat Kepesertaan Sektor Informal atas Kemampuan Ekonomi dalam BPJS Kesehatan di Kota Surakarta
Authors: Yenni Khristiana
Published: October 2020

Sesuai pasal 14 Undang-Undang BPJS setiap warga negara Indonesia dan warga asing yang sudah berdiam di Indonesia minimal enam bulan wajib menjadi anggota BPJS Kesehatan. Peraturan Presiden Nomor 12 tahun 2013 tentang Jaminan Kesehatan mengklasifikasikan kepesertaan program Jaminan Kesehatan Nasional (JKN) dalam dua golongan yaitu Peserta Penerima Bantuan Iuran (PBI) dan Peserta Non Penerima Bantuan Iuran (Non PBI). Tujuan penelitian ini adalah untuk memprediksi faktor-faktor yang hubungan kepesertaan sektor informal (wiraswasta/pedagang) dalam BPJS Kesehatan mandiri.Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan data primer yang diperoleh dengan metode wawancara menggunakan instrumen penelitian berupa kuesioner kepada 100 peserta mandiri atau BPJS Kesehatan sektor informal di Wilayah Kota Surakarta dengan perhitungan slovin'. Teknik analisis data  yang digunakan adalah Regresi Linier Berganda. Hasil penelitian menunjukan bahwa variabel pengetahuan berpengaruh positif namun  tidak signifikan dalam memprediksi minat kepersertaan sektor informal dalam BPJS Kesehatan, variabel kemampuan ekonomi berpengaruh positif dan signifikan dalam memprediksi minat kepersertaan sektor informal dalam BPJS Kesehatan dan variabel persepsi berpengaruh positif namun tidak signifikan dalam memprediksi minat kepersertaan sektor informal dalam BPJS Kesehatan.
Asymptomatic free gas post Endoscopic Mucosal Resection (EMR) - Is surgical intervention always necessary?
Authors: Shafquat Zaman  , Hayaka Amada  , Pratik Bhattachayra  , Stephen Stonelake  , Mark Goldstein  , Misra Budhoo
Published: October 2020

Background& Objectives

Endoscopic mucosal resection (EMR) is an efficient, cost-effective and minimally-invasive mode of treatment of colonic polyps. Colonic perforation post EMR is one of the potential complications associated with this procedure. Some patients may present with asymptomatic free gas on imaging and therefore not necessarily require intervention.

Methods

We present a case series of patients undergoing EMR who were found to have intra-abdominal free gas or ‘bowel perforation’ on imaging post procedure. They were all asymptomatic and did not warrant emergency surgical intervention. In addition, we aim to provide a review of the existing literature on ‘bowel perforation’ post EMR and discuss its management.

Results & Conclusion

Through this case series we highlight the importance of assessing patients clinically and not treating the radiological findings alone. Clinicians must be aware of the possibility of patients with asymptomatic free gas post EMR as a direct result of the injectate during the procedure or due to the passage of air or CO2 from the distended colon. As the popularity of this procedure increases, it is crucial that clinicians, surgeons and endoscopists are all aware of its associated complications.
An overview on transmission of diseases in special reference to COVID-19 and potential targets to control this pandemic
Authors: Vibha Yadav  , Mrigendra Rajput  , Diwakar R.P  , Rajesh Kumar
Published: October 2020

With its initial outbreak in China, the virus was referred as "coronavirus". WHO has named it "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2). It has been described as the successor to SARS-CoV-1which is a positive-sense single-stranded RNA virus. The virus spreads mainly between people who are in close contact (less than two metres or six feet) through small droplets produced during coughing, sneezing, or talking. Infected people exhale the contaminated droplets which are then inhaled into the lungs, or settle on other non- infected people's faces his/her mucosae (mouth and nose) or conjunctiva (eyes) get exposed to potentially infective respiratory droplets to cause new infection. It mainly enters human cells by binding to the receptor angiotensin converting enzyme 2 (ACE2). Research works are in progress to find potential targets to control the pandemic. To control and treat the virus various targets are under study and these targets range from modulating host cell receptor for the virus entry to generate an effective adaptive immune response.
Presentación
Authors: Hugues Juan
Published: October 2020

El IPA ha sido fundado en 1968 por los Obispos y Prelados de siete jurisdicciones eclesiásticas: Cusco, Puno, Abancay, Juli, Ayaviri, Sicuani y Chuquibambilla. La idea había surgido desde 1966 y el Arzobispo del Cusco, Mons. Ricardo Durand Flores consiguió de la Iglesia Católica Alemana, mediante la organización Adveniat, el presupuesto necesario para llevar a cabo los cursillos y las investigaciones previas a la elaboración de líneas de acción pastoral para una Evangelización que respete y fomente los valores culturales del pueblo campesino aymara y quechua de la región sur-andina del Perú. La Sociedad Misionera Americana (Padres de Maryknoll) también proporcionó una importante ayuda económica inicial.
Una celebración mestiza del Cruz-Velakuy en el Cusco
Authors: Núñez del Prado Béjar Juan Víctor , Bobino Nievez Marco
Published: October 2020

El presente trabajo, se propone exponer una serie de hechos provenientes de la relación inter-clase en una festividad tradicional del Cusco, que originalmente pertenecía a la clase chola. En el presente caso, ha sido adoptada por un círculo de mestizos de clase media. Para esto, haremos primero, una descripción del desarrollo de dicha fiesta y luego sobre este fondo, proyectaremos los fenómenos en cuestión.
Impact of Multicultural Diversity on the Gender Stereotyping in Bapsi Sidhwa’s The Pakistani Bride through the Deconstructive Perspective
Authors: Rehman Muhammad Shakil ur , Khan Dr Abdul Hamid
Published: October 2020

The article analyzes the impact of multicultural fictional representation of the two female characters on the gender stereotyping in Bapsi Sidhwa’s The Pakistani Bride (1990) by applying Judith Butler’s gender approach. The novelist (1938) is a distinguishing Anglophone, post-colonial and diaspora writer in South Asia (Suleri, 2001) who is known to be the pioneer of Pakistani novel in English. Sidhwa’s portrayal of different cultural milieu in the novel under study is to highlight the impact on gender identification through the analysis of the performativity of the two brides, Zaitoon and Carol. The first lady, one of the key characters, confronts and challenges the tribal gender norms of a Pakistani society and the second bride mirroring of an American culture projecting of a diverse identification. The multicultural contextual background of the novel leads the debate to analyze how different gender roles are performed by each of the brides to support the research contention that gender is wrought not by sexual categorization but by socio-cultural stereotyping. Therefore, the cultural differences in the book necessarily require fluid shades of gender identification accordingly. It is the targeted objective of the research framework applied by the study that gender is an action, it is a fluid and instable feature as has been manifested through the performance of the focused characters in the novel.
RURAL AND REGIONAL DEVELOPMENT POLICIES IN EUROPE: SOCIAL FARMING IN THE COMMON STRATEGIC FRAMEWORK (HORIZON 2020)
Authors: TULLA Antoni Francesc , VERA Ana , BADIA Anna , GUIRADO Carles , VALLDEPERAS Natàlia
Published: October 2020

Social Farming (SF) is an emerging sector in the rural European context, but the European Economic and Social Committee (2013/C 44/07) emphasizes that SF should be planned and implemented under the new 2014-20 rural development policy because of the positive results obtained. The SF concept can be associated with agriculture as a multifunctional activity, giving agricultural practice new meanings and functions and incorporating social services, medical treatment and rehabilitation, and educational training and support. In addition, agriculture must be considered as a means of employment and social integration for groups as diverse as individuals who are unemployed or living with mental retardation, mental disorders, or addictions, among others. As a result, innovative SF activities are contributing to the social economy, rural and regional development, and support for a new agro-social paradigm. These are mainly activities linked with the endogenous resources of the territory that generate new enterprises, together with complementary activities that consolidate an economic network as the basis for regional development.
RESIDENTS’ PERSPECTIVES TOWARDS CONSERVATION IN GEORGE TOWN WORLD HERITAGE CITY: A POST-UNESCO LISTING SCENARIO
Authors: LIM Yoke Mui , KHOO Suet Leng , CH’NG Kean Sing
Published: October 2020

Being inscribed as a UNESCO World Heritage City since 2008, this scenario calls into question the voices, the participation and the aspirations of George Town residents themselves in the process of planning and conserving their city. As an extension of a similar project undertaken in 2006, prior to the UNESCO listing, the present study sought to explore and understand the residents’ perceptions and preferences of George Town as a Heritage City after the UNESCO listing. Using the same set of samples (i.e. 400 inner city residents), the findings from this study revealed the change of residents’ preference as well as their appreciation towards the value of heritage and its economic potential. More respondents are supportive on the protection of heritage buildings and maintaining a heritage city. The older generations are the advocates of the heritage houses and they are more willing to pay higher prices to own a heritage house in the city. heritage awareness, urban conservation, resident perspectives, George Town.
FINANCES AND GOVERNANCE OF URBAN LOCAL BODIES: AN APPROACH OF URBAN DEVELOPMENT PERSPECTIVE FROM A DEVELOPING COUNTRY (INDIA)
Authors: PAUL Suman
Published: October 2020

With rapid urbanisation and the pressure on urban areas for service delivery, the role of urban local governments is undoubtedly becoming important and, here, their financial capacity can hold the key. At the same time, there are several issues in urban governance that need to be addressed yet. Delegation of decision making powers to urban local bodies (ULBs), which are traditionally considered as a part of the system of State government and acting on behalf of it, is one of them. The constitutional mechanisms like inter-governmental fiscal transfers were an attempt to reduce the gap of ULBs, but they were not effective in implementation at ground. It has become imperative now to understand the financial position of ULBs in order to move forward with the new means of fund flow. This paper presents a cross sectional analysis of the finance of 27 ULBs in North 24 Parganas District of West Bengal, India in terms of their financial base and its adequacy vis-à-vis norms, and their revenue and expenditure performance. Using certain ratios, the relative performance of municipalities on dependency measures was also assessed. The implications of finances of ULBs, in terms of raising resources, improving inter-governmental transfers and charting new mechanisms are also discussed. Lastly, an approach has been made to develop an index, i.e. Urban Governance Index (UGI) to a better understanding of the per-capita expenditure scenario of ULBs.