bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from Inherited Variation in miR-290 Expression Suppresses Breast Cancer Progression by Targeting the Metastasis Susceptibility Gene Arid4b
Authors: Goldberger Natalie , Walker Renard C. , Kim Chang Hee , Winter Scott , Hunter Kent W.
Published: April 2023

PDF file - 408K, Validation of enhanced ER signaling was confirmed by evaluating the expression level of ER-responsive genes in the 6dt1 tumors by microarray and qRT-PCR.
Supplementary Figure 3 from Inherited Variation in miR-290 Expression Suppresses Breast Cancer Progression by Targeting the Metastasis Susceptibility Gene Arid4b
Authors: Goldberger Natalie , Walker Renard C. , Kim Chang Hee , Winter Scott , Hunter Kent W.
Published: April 2023

PDF file - 114K, miR-290-3p and miR-290-5p expression levels were measured by qRT-PCR in the miR-290 tumors
Supplementary Table 3 from Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
Authors: Lee Genee Y. , Haverty Peter M. , Li Li , Kljavin Noelyn M. , Bourgon Richard , Lee James , Stern Howard , Modrusan Zora , Seshagiri Somasekar , Zhang Zemin , Davis David , Stokoe David , Settleman Jeffrey , de Sauvage Frederic J. , Neve Richard M.
Published: April 2023

XLSX file - 419K, List of genes screened in the first and second round screens.
Supplementary Table 2 from Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
Authors: Lee Genee Y. , Haverty Peter M. , Li Li , Kljavin Noelyn M. , Bourgon Richard , Lee James , Stern Howard , Modrusan Zora , Seshagiri Somasekar , Zhang Zemin , Davis David , Stokoe David , Settleman Jeffrey , de Sauvage Frederic J. , Neve Richard M.
Published: April 2023

XLSX file - 112K, GISTIC analysis of tumour samples.
Supplementary Figure 1 from Preclinical Evidence That PD1 Blockade Cooperates with Cancer Vaccine TEGVAX to Elicit Regression of Established Tumors
Authors: Fu Juan , Malm Ian-James , Kadayakkara Deepak K. , Levitsky Hy , Pardoll Drew , Kim Young J.
Published: April 2023

PDF file - 3450KB, Colocalization of CD8 T-cells with PD-L1 expression.
Supplementary Table 2 from Notch3 Pathway Alterations in Ovarian Cancer
Authors: Hu Wei , Liu Tao , Ivan Cristina , Sun Yunjie , Huang Jie , Mangala Lingegowda S. , Miyake Takahito , Dalton Heather J. , Pradeep Sunila , Rupaimoole Rajesh , Previs Rebecca A. , Han Hee Dong , Bottsford-Miller Justin , Zand Behrouz , Kang Yu , Pecot Chad V. , Nick Alpa M. , Wu Sherry Y. , Lee Ju-Seog , Sehgal Vasudha , Ram Prahlad , Liu Jinsong , Tucker Susan L. , Lopez-Berestein Gabriel , Baggerly Keith A. , Coleman Robert L. , Sood Anil K.
Published: April 2023

PDF file - 183K, The siRNA and Primer Sequences.
Supplementary Table 1 from Notch3 Pathway Alterations in Ovarian Cancer
Authors: Hu Wei , Liu Tao , Ivan Cristina , Sun Yunjie , Huang Jie , Mangala Lingegowda S. , Miyake Takahito , Dalton Heather J. , Pradeep Sunila , Rupaimoole Rajesh , Previs Rebecca A. , Han Hee Dong , Bottsford-Miller Justin , Zand Behrouz , Kang Yu , Pecot Chad V. , Nick Alpa M. , Wu Sherry Y. , Lee Ju-Seog , Sehgal Vasudha , Ram Prahlad , Liu Jinsong , Tucker Susan L. , Lopez-Berestein Gabriel , Baggerly Keith A. , Coleman Robert L. , Sood Anil K.
Published: April 2023

PDF file - 96K, Notch Pathway Alterations in Patients with HGS-OvCa.
Supplementary Table 1 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: April 2023

PDF file - 93KB, PCR Primers and TaqMan qPCR Probes.
Supplementary Figure 2 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: April 2023

PDF file - 198KB, Mammary tumor growth and metastasis in Tg(TVA)+RCAS-PyMT and Tg(NCOA1)x Tg(TVA)+RCAS-PyMT mice.
Supplementary Figure 1 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: April 2023

PDF file - 368KB, Mammary gland morphogenesis and epithelial proliferation of Tg(NCOA1) mice.
Supplementary Methods, Figure Legends, Tables 1 - 9 from Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy
Authors: Lindner Andreas U. , Concannon Caoimhín G. , Boukes Gerhardt J. , Cannon Mary D. , Llambi Fabien , Ryan Deborah , Boland Karen , Kehoe Joan , McNamara Deborah A. , Murray Frank , Kay Elaine W. , Hector Suzanne , Green Douglas R. , Huber Heinrich J. , Prehn Jochen H.M.
Published: April 2023

PDF file - 237K, Supplementary Table 1: Translation of protein interactions into Ordinary Differential Equations. Supplementary Table 2: Pseudo-reactions for degradation and degradation rates as used in the model. Supplementary Table 3: Pseudo-reactions and kinetics for inhibition of BH3 only proteins and effectors BAK and BAX by anti-apoptotic proteins. Supplementary Table 4: BAK and BAX activation and BAK inhibition by VDAC2. Supplementary Table 5: Effector homo-oligomerization. Supplementary Table 6: Modeling apoptosis sensitizers ABT-737 and ApoG2. Supplementary Table 7 Two tBID chimeras were modeled to reproduce the findings of Llambi et al. Supplementary Table 8: BCL2 protein quantification of CRC cell lines. Supplementary Table 9: BCL2 protein quantification of CRC patient samples.
Supplementary Figure 1 from Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy
Authors: Lindner Andreas U. , Concannon Caoimhín G. , Boukes Gerhardt J. , Cannon Mary D. , Llambi Fabien , Ryan Deborah , Boland Karen , Kehoe Joan , McNamara Deborah A. , Murray Frank , Kay Elaine W. , Hector Suzanne , Green Douglas R. , Huber Heinrich J. , Prehn Jochen H.M.
Published: April 2023

PDF file - 66K, Temporal protein profiles for HeLa cells.
Supplementary Table 8 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

XLSX file - 39K, Results of upstream activator and regulator IPA analysis based on the gene list in Supplementary Table 5.
Supplementary Table 7 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

XLSX file - 15K, Set of most significantly enriched canonical pathways as deterermined by IPA analysis based on the gene list in Supplementary Table 5.
Supplementary Table 5 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

XLSX file - 42K, Set of 894 genes with a univariate CoxPH q-value < 0.10 that were subjected to pathway enrichment and upstream analyses using Ingenuity Pathway Analysis (IPA).
Supplementary Figures 1-6 from CD40-Mediated Activation of Chronic Lymphocytic Leukemia Cells Promotes Their CD44-Dependent Adhesion to Hyaluronan and Restricts CCL21-Induced Motility
Authors: Girbl Tamara , Hinterseer Elisabeth , Grössinger Eva Melanie , Asslaber Daniela , Oberascher Karin , Weiss Lukas , Hauser-Kronberger Cornelia , Neureiter Daniel , Kerschbaum Hubert , Naor David , Alon Ronen , Greil Richard , Hartmann Tanja Nicole
Published: April 2023

PDF file - 245K, Supplementary Figure S1: Activated, autologous T cells induce CLL cell proliferation. Supplementary Figure S2: CD40L activated CLL cells fully retain their chemotactic response towards CCL21. Supplementary Figure S3: PMA/ionomycin and IgM cross-linking induces FL-HA binding. Supplementary Figure S4: CD44 surface expression on CLL patients does not differ between clinical risk groups. Supplementary Figure S5: The CLL cell subpopulation remaining CD44v6 negative after CD40L-activation displays low activation levels. Supplementary Figure S6: The mAbs used for immunoblotting specifically recognize panCD44 and CD44v6
Supplementary Figure 4 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

PDF file - 1288K, Distribution of genes with FPKM > 1. Genes are binned into deciles of percentage of samples in which the FPKM was > 1. Thus for a gene with FPKM > 1 in 65% of samples, the gene would be included in 60-70% bin. Y-axis is the number of genes in each decile.
Supplementary Figure 3 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

PDF file - 1172K, Log2 FPKM+1 values are plotted for the six samples that were sequenced in duplicate. Plots include data for the 5265 detected genes used in the biomarker analysis. R-squared values are indicated for the best fit linear curve for each duplicate sample.
Supplementary Figures 1 - 6 from Durable Adoptive Immunotherapy for Leukemia Produced by Manipulation of Multiple Regulatory Pathways of CD8+ T-Cell Tolerance
Authors: Berrien-Elliott Melissa M. , Jackson Stephanie R. , Meyer Jennifer M. , Rouskey Craig J. , Nguyen Thanh-Long M. , Yagita Hideo , Greenberg Philip D. , DiPaolo Richard J. , Teague Ryan M.
Published: April 2023

PDF file - 643K, Supplementary Figure S1. Surface expression of co-stimulatory and co-inhibitory molecules on FBL tumor cells. Supplementary Figure S2. Transferred T cells are deleted via apoptosis. Supplementary Figure S3. Survival of transferred T cells is not sufficient for acquisition of effector function. Supplementary Figure S4. Systemic inflammation and provision of high-dose IL-2 fail to prevent deletion of adoptively transferred CD8+ T cells. Supplementary Figure S5. LAG3 blockade has limited additional impact on survival of transferred T cells. Supplementary Figure S6. LAG3 blockade combines with PD-1/CTLA4 blockade to promote expansion and effector function by transferred T cells.
Supplementary Figure 1 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

PDF file - 2194K, RNAseq data from the IGFBP3 gene in the IGV browser for representative FFPE samples (top four tracks) and TCGA prostate samples (bottom three tracks) showing intronic reads.
Supplementary Materials, Figures 1 - 2, Table 1 from The RAD51-Stimulatory Compound RS-1 Can Exploit the RAD51 Overexpression That Exists in Cancer Cells and Tumors
Authors: Mason Jennifer M. , Logan Hillary L. , Budke Brian , Wu Megan , Pawlowski Michal , Weichselbaum Ralph R. , Kozikowski Alan P. , Bishop Douglas K. , Connell Philip P.
Published: April 2023

PDF file - 403KB, Supplemental Figure 1. Quantifications of western blots. Supplemental Figure 2. Knockdown of RAD51 in PC3 does not protect cells from the toxicity of ionizing radiation. Supplemental Table 1. Quantifications of statistical significance are displayed for the RS-1 toxicity data that are displayed in Figure 2. Supplemental Methods. Chemical synthesis of compounds.
Supplementary Figure 6 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: April 2023

PDF file - 3310K, JAM-B Fc binds to JAM-Cpos cells, independently of alpha-4 integrin.
Supplementary Figure 5 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: April 2023

PDF file - 2674K, Controls for in vivo short-term homing assays
Supplementary Figure 4 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: April 2023

PDF file - 4341K, Incubation of B cells with anti-JAM-C antibodies does not affect expression of activation markers or adhesion molecules
Supplementary Figure 1 from Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis
Authors: Berger Penny L. , Frank Sander B. , Schulz Veronique V. , Nollet Eric A. , Edick Mathew J. , Holly Brittany , Chang Ting-Tung A. , Hostetter Galen , Kim Suwon , Miranti Cindy K.
Published: April 2023

PDF file - 343KB, Marker Validation of Differentiated Cells.
Supplementary Materials and Methods from Regulation of Lung Cancer Metastasis by Klf4-Numb–like Signaling
Authors: Vaira Valentina , Faversani Alice , Martin Nina M. , Garlick David S. , Ferrero Stefano , Nosotti Mario , Kissil Joseph L. , Bosari Silvano , Altieri Dario C.
Published: April 2023

PDF File - 4789K, REGULATION OF LUNG CANCER METASTASIS BY Klf4-Numb-like SIGNALING.
Supplementary Figure 3 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: April 2023

PDF file - 128K, Target engagement was validated for several cell lines via western blot analyses. Here, RPE-1, SK-N-AS, KELLY and NB-1691 cells are shown following treatment with increasing concentrations of MK-8776 and MK-1775 for 16h. Inhibition of Chk1 (via MK-8776) and Cdc2 phosphorylation (via MK-1775) was observed in sensitive cell lines
upplementary Data Legend from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: April 2023

upplementary Data Legend PDF file - 94K, Supplementary data legend
Supplementary Figure 3 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: April 2023

PDF file - 1374K, Tubulin tyrosination state in NF2 negative cells.
Supplementary Figure 2 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: April 2023

PDF file - 1573K, Validation of anti-NF2 antibody specificity.
Supplementary Table 1, Figures 1 - 2 from Imatinib Radiosensitizes Bladder Cancer by Targeting Homologous Recombination
Authors: Qiao Boling , Kerr Martin , Groselj Blaz , Teo Mark T.W. , Knowles Margaret A. , Bristow Robert G. , Phillips Roger M. , Kiltie Anne E.
Published: April 2023

PDF file - 287K, Supplementary Table 1. Target regions for Ku80 and RAD51 siRNA. Supplementary Figure 1. Western blots of Ku80 and RAD51 in RT112 stable shRNA clones. Supplementary Figure 2. Full length western blots.
Supplementary Figure 5 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: April 2023

PDF file - 654K, Endogenous and overexpressed CEP57 show a centrosomal expression pattern in LNCaP prostate cancer cells.
Supplementary Figure 4 from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: April 2023

PDF file - 56K, Proliferation rate analysis.
Supplementary Figure 4 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: April 2023

PDF file - 311K, CEP57 increases the abundance of acetylated α-tubulin.
Supplementary Figure 2 from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: April 2023

PDF file - 47K, Mosaic phosphorylation of rpS6 in wild type islets.
Supplementary Figure 1 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: April 2023

PDF file - 478K, CEP57 localizes to the centrosome throughout the cell division cycle.
Supplementary Materials and Methods from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 136KB
Supplementary Figure S7 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Figure S7 PDF File - 21K, Knockdown of Arkadia in MTLN3E and B16 cells inhibits TGF-�-induced Smad3-dependent transcription
Supplementary Figure 7 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 103KB, Nos1 is dispensable for the growth of CXCL14 fibroblasts under conditions of oxidative stress but important for their paracrine-mediated effects.
Supplementary Figure 2 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 46KB, Nos1 knockdown in CXCL14-fibroblasts.
Supplementary Figure 6 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: April 2023

PDF file - 163K, Homozygous CHD1 deletion in areas of prostatic intraepithelial neoplasia (PIN) and invasive cancer cells. Overwiew of a hematoxylin- and eosin stained tissue section containing areas of PIN (a, b) and invasive cancer (c). Corresponding FISH images show complete loss of CHD1 FISH signals (red) in PIN and cancer cells but not in stroma cells indicated by an asterix. The control FISH signals (green) correspond to centromere 6.
Supplementary Figures 1 - 5 from Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation
Authors: Lee Cleo Yi-Fang , Lin Yuan , Bratman Scott V. , Feng Weiguo , Kuo Angera H. , Scheeren Ferenc A. , Engreitz Jesse M. , Varma Sushama , West Robert B. , Diehn Maximilian
Published: April 2023

PDF file - 581K, Breast TICs are enriched in the CD24HiCD49fHi subpopulation (S1); Expression of HER receptors and ligands in breast cancer cell lines (S2); HER2 inhibition reduces the EpCAM- TIC-like subpopulation of SUM149 cells (S3); Breast TICs are enriched in the EPCAM+CD49f+ subpopulation of a triple-negative patient-derived xenograft breast tumor BCA70 (S4); Dual inhibition of HER2 and EGFR targets breast TICs in patient-derived xenograft BCA71 (S5).
Supplementary Figure 5 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: April 2023

PDF file - 636K, Impact of CHD1 on colony formation, soft agar growth and cell invasiveness. a) Effect of CHD1 overexpression on cell growth. DU-145 cells were transfected with expression vectors encoding CHD1, PLNGY (control) and the known tumor suppressor genes RB1 and PTEN. Effect of CHD1 depletion on cell growth. DU-145 cells were transfected with shCHD1 vector. The control group consisted of shGFP, shRB1 and shPTEN vectors. Cells were selected with puromycin and cultured for two weeks, and colonies were fixed with methanol and stained with Giemsa. b) Soft agar assay showing the impaired anchorage-independent growth of shCHD1 PC-3 cells and control shNeg cells. Representative images of the stained colonies are shown. The bars represent the average number of colonies. c) CHD1 knockdown impairs invasion of PC-3 (shCHD1) cells through matrigel as compared to shNeg control cells. Photographs show representative fields of crystal-violet stained invading cells.
Supplementary Figure 4 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: April 2023

PDF file - 44K, Overexpression of RB1 and PTEN in PC-3 cells transfected with PSG5L-RB1 and PSG5L-PTEN as compared to the control vector PLNGY. Lysates were analysed for RB1 (a) and PTEN (b) by immunoblot analysis. Tubulin immunoblot served as loading control.
Supplementary Figure 3 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: April 2023

PDF file - 92K, Impact of sh-RNA mediated knockdown of CHD1 (a), RB1 (b), PTEN (c) and mTOR (d) knockdown on mRNA and protein levels in BPH-1 cells by Taqman.
Supplementary Methods from Effects of Notch Signaling on Regulation of Myeloid Cell Differentiation in Cancer
Authors: Cheng Pingyan , Kumar Vinit , Liu Hao , Youn Je-In , Fishman Mayer , Sherman Simon , Gabrilovich Dmitry
Published: April 2023

PDF - 40K, Description of additional methods and procedures used in the study.
Supplementary Materials and Methods from Metalloprotease-Mediated Tumor Cell Shedding of B7-H6, the Ligand of the Natural Killer Cell–Activating Receptor NKp30
Authors: Schlecker Eva , Fiegler Nathalie , Arnold Annette , Altevogt Peter , Rose-John Stefan , Moldenhauer Gerhard , Sucker Antje , Paschen Annette , von Strandmann Elke Pogge , Textor Sonja , Cerwenka Adelheid
Published: April 2023

PDF file - 87KB
Supplementary Figure Legends from Metalloprotease-Mediated Tumor Cell Shedding of B7-H6, the Ligand of the Natural Killer Cell–Activating Receptor NKp30
Authors: Schlecker Eva , Fiegler Nathalie , Arnold Annette , Altevogt Peter , Rose-John Stefan , Moldenhauer Gerhard , Sucker Antje , Paschen Annette , von Strandmann Elke Pogge , Textor Sonja , Cerwenka Adelheid
Published: April 2023

PDF file - 70KB
Supplementary Figure 5 from Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity
Authors: Risinger A.L. , Li J. , Bennett M.J. , Rohena C.C. , Peng J. , Schriemer D.C. , Mooberry S.L.
Published: April 2023

PDF file - 64K, The effect of AJ on the mass of the beta213-230 peptic peptide.
Supplementary Figure Legend from Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
Authors: Lin Wan-chi , Rajbhandari Nirakar , Liu Chengbao , Sakamoto Kazuhito , Zhang Qian , Triplett Aleata A. , Batra Surinder K. , Opavsky Rene , Felsher Dean W. , DiMaio Dominick J. , Hollingsworth Michael A. , Morris John P. , Hebrok Matthias , Witkiewicz Agnieszka K. , Brody Jonathan R. , Rui Hallgeir , Wagner Kay-Uwe
Published: April 2023

PDF file - 40K
Movie 5 from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Movie 5 AVI file - 6439K, Time-lapse videomicroscopy of EB1-GFP comets in siRNA-silenced HeLa cells
Movie 3 from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Movie 3 AVI file - 997K, Time-lapse videomicroscopy of wound healing assay using GFP-transiently transfected D3H2LN cells
Supplementary Video 4 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation
Authors: Martínez-Bosch Neus , Fernández-Barrena Maite G. , Moreno Mireia , Ortiz-Zapater Elena , Munné-Collado Jessica , Iglesias Mar , André Sabine , Gabius Hans-Joachim , Hwang Rosa F. , Poirier Françoise , Navas Carolina , Guerra Carmen , Fernández-Zapico Martin E. , Navarro Pilar
Published: April 2023

AVI file - 2891KB, Supplementary video 4 (Related to Supplementary Figure 4C). Time lapse video microscopy in SK-PC-1 cells infected with an scrambled shRNA (shCtl). Frames were collected every 15 min for 12h.
Supplementary Figure 3 from EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells against Ionizing Radiation
Authors: Wang Meng , Kern Ashley M. , Hülskötter Marieke , Greninger Patricia , Singh Anurag , Pan Yunfeng , Chowdhury Dipanjan , Krause Mechthild , Baumann Michael , Benes Cyril H. , Efstathiou Jason A. , Settleman Jeff , Willers Henning
Published: April 2023

PDF file - 167KB, EGFR and PKCa are co-regulators of Aurora B kinase-mediated chromatin condensation in interphase.
Supplementary Figure 2 from EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells against Ionizing Radiation
Authors: Wang Meng , Kern Ashley M. , Hülskötter Marieke , Greninger Patricia , Singh Anurag , Pan Yunfeng , Chowdhury Dipanjan , Krause Mechthild , Baumann Michael , Benes Cyril H. , Efstathiou Jason A. , Settleman Jeff , Willers Henning
Published: April 2023

PDF file - 108KB, EGFR nuclear translocation and NHEJ do not correlate with EGFR-dependent suppression of IR-induced DSBs.
Supplementary Movie 1 from Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides
Authors: Savariar Elamprakash N. , Felsen Csilla N. , Nashi Nadia , Jiang Tao , Ellies Lesley G. , Steinbach Paul , Tsien Roger Y. , Nguyen Quyen T.
Published: April 2023

AVI file - 1355K, Supplementary Movie - Movie of mouse bearing GFP-labeled 8119 primary auricular tumor with a cervical lymph node with partial cancer invasion 2 hours following IV injection of RACPP1. Green color is GFP labeling seen in the primary tumorand on the lateral aspect of the involved lymph node. Images with aqua pseudocolor are generated from the Cy5 emission fluorescence intensity alone superimposed on white light reflectance. Images with multihued pseudocolor varying from dark blue (low ratio) to red (high ratio) are generated from the Cy5/Cy7 ratio at every pixel. Note that region of cancer invasion (GFP positive cells seen as green) in the cervical lymph node correlate with the region of highest Cy5/Cy7 ratio (seen as red pseudocolor).
Supplementary Methods from Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides
Authors: Savariar Elamprakash N. , Felsen Csilla N. , Nashi Nadia , Jiang Tao , Ellies Lesley G. , Steinbach Paul , Tsien Roger Y. , Nguyen Quyen T.
Published: April 2023

PDF file - 40K
Supplementary Figure 3 from Rhythmic Control of the ARF-MDM2 Pathway by ATF4 Underlies Circadian Accumulation of p53 in Malignant Cells
Authors: Horiguchi Michiko , Koyanagi Satoru , Hamdan Ahmed M. , Kakimoto Keisuke , Matsunaga Naoya , Yamashita Chikamasa , Ohdo Shigehiro
Published: April 2023

PDF file - 449K, Temporal binding profiles of ATF4 to the CARE in the mouse p19Arf gene 5'-flanking region in oncogenic wild-type cells.
Supplementary Figure 3 from Loss of TGF-β Adaptor β2SP Activates Notch Signaling and SOX9 Expression in Esophageal Adenocarcinoma
Authors: Song Shumei , Maru Dipen M. , Ajani Jaffer A. , Chan Chia-Hsin , Honjo Soichiro , Lin Hui-Kuan , Correa Arlene , Hofstetter Wayne L. , Davila Marta , Stroehlein John , Mishra Lopa
Published: April 2023

PDF file - 1127K, Deletion of β2SP in MEFs leads to up-regulation of EMT transcription factors. Indirect immunofluorescence was performed on MEFs cell with or without b2SP deletion cells using anti-Slug or anti-Snail antibodies and followed by DAPI counterstaining (blue). The merge of Slug or Snail (red) with DAPI (blue) is also shown.
Supplementary Figure 7 from STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
Authors: Peña Cristina , Céspedes María Virtudes , Lindh Maja Bradic , Kiflemariam Sara , Mezheyeuski Artur , Edqvist Per-Henrik , Hägglöf Christina , Birgisson Helgi , Bojmar Linda , Jirström Karin , Sandström Per , Olsson Eleonor , Veerla Srinivas , Gallardo Alberto , Sjöblom Tobias , Chang Andy C.-M. , Reddel Roger R. , Mangues Ramón , Augsten Martin , Östman Arne
Published: April 2023

PDF file - 6319K, Relationship between size of primary tumor and intravasation. Analyses of lymphatic vessel, cancer stem cell and macrophage density in primary tumors.
Supplementary Figure 3 from STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
Authors: Peña Cristina , Céspedes María Virtudes , Lindh Maja Bradic , Kiflemariam Sara , Mezheyeuski Artur , Edqvist Per-Henrik , Hägglöf Christina , Birgisson Helgi , Bojmar Linda , Jirström Karin , Sandström Per , Olsson Eleonor , Veerla Srinivas , Gallardo Alberto , Sjöblom Tobias , Chang Andy C.-M. , Reddel Roger R. , Mangues Ramón , Augsten Martin , Östman Arne
Published: April 2023

PDF file - 1652K, Analysis of associations between STC1 expression and stroma abundance and survival.
Supplementary Table 6 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

XLSX file - 14KB, Histoscores of SNAI2, AR and RUNX2 in clinical samples.
Supplementary Figure Legends from API5 Confers Tumoral Immune Escape through FGF2-Dependent Cell Survival Pathway
Authors: Noh Kyung Hee , Kim Seok-Ho , Kim Jin Hee , Song Kwon-Ho , Lee Young-Ho , Kang Tae Heung , Han Hee Dong , Sood Anil K. , Ng Joanne , Kim Kwanghee , Sonn Chung Hee , Kumar Vinay , Yee Cassian , Lee Kyung-Mi , Kim Tae Woo
Published: April 2023

PDF file - 97KB
Supplementary Table 3 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

XLSX file - 78KB, Type I DHT and DHT dox-induced gene expression values from the microarray.
Supplementary Table 1 from Stalling the Engine of Resistance: Targeting Cancer Metabolism to Overcome Therapeutic Resistance
Authors: Butler Ethan B. , Zhao Yuhua , Muñoz-Pinedo Cristina , Lu Jianrong , Tan Ming
Published: April 2023

PDF file - 69K, Supplementary Table 1: Emerging metabolic targets and the inhibitors that have shown promise to overcome cancer cell resistance to therapeutics.
Supplementary Table 1 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

XLSX file - 14KB, Primers used for qPCR analysis.
Supplementary Figure 7 from Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer
Authors: Alizadeh Darya , Trad Malika , Hanke Neale T. , Larmonier Claire B. , Janikashvili Nona , Bonnotte Bernard , Katsanis Emmanuel , Larmonier Nicolas
Published: April 2023

PDF file - 163K, Effects of doxorubicin on MDSC expression of immunosuppressive factors and on MDSC differentiation.
Supplementary Figure 3 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

PDF file - 123KB, SNAI2 protein in LNCaP/Rx2dox cells.
Supplementary Figure 6 from Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer
Authors: Alizadeh Darya , Trad Malika , Hanke Neale T. , Larmonier Claire B. , Janikashvili Nona , Bonnotte Bernard , Katsanis Emmanuel , Larmonier Nicolas
Published: April 2023

PDF file - 120K, Effects of doxorubicin on the suppressive function of residual MDSC.
Supplementary Figure 2 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

PDF file - 134KB, Effect of RUNX2 on DHT signaling in 22RV1 cells.
Supplementary Figure 1 from Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness
Authors: Little Gillian H. , Baniwal Sanjeev K. , Adisetiyo Helty , Groshen Susan , Chimge Nyam-Osor , Kim Sun Young , Khalid Omar , Hawes Debra , Jones Jeremy O. , Pinski Jacek , Schones Dustin E. , Frenkel Baruch
Published: April 2023

PDF file - 115KB, Effect of DHT on RUNX2 signaling.
Data Supplement from Microbiota Modulate Tumoral Immune Surveillance in Lung through a γδT17 Immune Cell-Dependent Mechanism
Authors: Cheng Min , Qian Liting , Shen Guodong , Bian Geng , Xu Tingjuan , Xu Weiping , Shen Gan , Hu Shilian
Published: April 2023

Supplemental materials and methods
Supplementary Methods from Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/β-Catenin Pathway Activation via Interaction with CD44
Authors: Zhu Xiaoping , Morales Fabiana C. , Agarwal Nitin Kumar , Dogruluk Turgut , Gagea Mihai , Georgescu Maria-Magdalena
Published: April 2023

PDF file - 30K
Supplementary Table S4 from FOXP3 Regulates Sensitivity of Cancer Cells to Irradiation by Transcriptional Repression of BRCA1
Authors: Li Weiquan , Katoh Hiroto , Wang Lizhong , Yu Xiaochun , Du Zhanwen , Yan Xiaoli , Zheng Pan , Liu Yang
Published: April 2023

Supplementary Table S4 XLS file - 19K, primer sequences
Supplementary Table S2 from FOXP3 Regulates Sensitivity of Cancer Cells to Irradiation by Transcriptional Repression of BRCA1
Authors: Li Weiquan , Katoh Hiroto , Wang Lizhong , Yu Xiaochun , Du Zhanwen , Yan Xiaoli , Zheng Pan , Liu Yang
Published: April 2023

Supplementary Table S2 XLS file - 12K, Direct foxp3 targets involved in DNA repair
Supplementary Methods, Figures 1 - 14, Tables 1 - 5 from Sphingosine Kinase 2 Promotes Acute Lymphoblastic Leukemia by Enhancing MYC Expression
Authors: Wallington-Beddoe Craig T. , Powell Jason A. , Tong Daochen , Pitson Stuart M. , Bradstock Kenneth F. , Bendall Linda J.
Published: April 2023

PDF file - 1070KB, Supplementary methods, Tables S1-S5 and Figures S1-S14 Table S1. Patient Information Table S2. Primers. Table S3. Regulation of c-Myc Target Genes by SK2 Inhibition Table S4. Gene Enrichment Analysis for All Nine Cell Lines. Table S5. Effect of ABC294640 on S1P plasma levels in mice. Figure S1. Inhibition of SK activity by ABC294640 and PF543. Figure S2. Gating strategy for the sorting of BM derived B-cell progenitors for transduction with BCR/ABL. Figure S3 B-cell progenitor fractions from the bone marrow of WT and SK2-/- mice was determined by flow cytometry Figure S4. SK1 expression following SK2 inhibition or deletion. Figure S5. Lack of effect of ABC294640 on normal bone marrow cells. Figure S6. Morphology of cells treated with ABC294640. Figure S7. Lack of segregation of ALL samples treated with SK1-I. Figure S8. Confirmation of gene regulation. Figure S9. Gene expression segregates ABC294640 treated cells from controls in a validation cohort. Figure S10. Lack of effect of SK1 inhibition on MYC expression. Figure S11. Reduced c-Myc expression following SK2 knockdown. Figure S12 Segregation of ABC294640 and control treated cells using MYC gene signatures. Figure S13. ABC294640 reduces S1P associated with HDAC2 and over expression of MYC protects from the effects of ABC294640. Figure S14. Interactions between various agents and SK2 Inhibition.
Supplementary Figure Legend from Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L
Authors: Bodogai Monica , Lee Chang Catalina , Wejksza Katarzyna , Lai Jinping , Merino Maria , Wersto Robert P. , Gress Ronald E. , Chan Andrew C. , Hesdorffer Charles , Biragyn Arya
Published: April 2023

PDF file - 79K
Supplementary Figure 6 from Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L
Authors: Bodogai Monica , Lee Chang Catalina , Wejksza Katarzyna , Lai Jinping , Merino Maria , Wersto Robert P. , Gress Ronald E. , Chan Andrew C. , Hesdorffer Charles , Biragyn Arya
Published: April 2023

PDF file - 172K, tBregs express low levels of 4-1BBL
Supplementary Figure 5 from Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L
Authors: Bodogai Monica , Lee Chang Catalina , Wejksza Katarzyna , Lai Jinping , Merino Maria , Wersto Robert P. , Gress Ronald E. , Chan Andrew C. , Hesdorffer Charles , Biragyn Arya
Published: April 2023

PDF file - 96K, In vivo inactivation of tBregs with BLC-arp/CpG-ODN induces antitumor T cell responses
Supplementary Figure Legend from Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38α Signaling Pathway
Authors: Liu Kangdong , Yu Donghoon , Cho Yong-Yeon , Bode Ann M. , Ma Weiya , Yao Ke , Li Shengqing , Li Jixia , Bowden G. Tim , Dong Ziming , Dong Zigang
Published: April 2023

PDF file - 89K
Supplementary Figure 4 from Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38α Signaling Pathway
Authors: Liu Kangdong , Yu Donghoon , Cho Yong-Yeon , Bode Ann M. , Ma Weiya , Yao Ke , Li Shengqing , Li Jixia , Bowden G. Tim , Dong Ziming , Dong Zigang
Published: April 2023

PDF file - 304K, The protein phosphorylation spectrum activated by SUV irradiation at various time points. N/TERT-1 cells were irradiated with SUV (60 kJ UVA/m2/3.6 kJ UVB/m2) and harvested at various times to produce a time course. Protein extracts (500 μg) were used for phospho-kinase array analysis. Array spots were visualized by ECL kit. The density of the each duplicated array spot in Figure 4A was measured as described in Materials and Methods. The table shows the fold change in SUV-induced phosphorylation of all 46 kinases and transcription factors compared to untreated control. Data are shown as an average of duplicate samples.
Supplementary Figure 1 from Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L
Authors: Bodogai Monica , Lee Chang Catalina , Wejksza Katarzyna , Lai Jinping , Merino Maria , Wersto Robert P. , Gress Ronald E. , Chan Andrew C. , Hesdorffer Charles , Biragyn Arya
Published: April 2023

PDF file - 1209K, tBregs express low levels of CD20
Supplementary Table S6 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Table S6 PDF file - 316K, SLC7A1
Supplementary Table S4 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Table S4 PDF file - 358K, List of filtered genes used in our experimental setup
Supplementary Methods from Prooncogenic Factors miR-23b and miR-27b Are Regulated by Her2/Neu, EGF, and TNF-α in Breast Cancer
Authors: Jin Lianjin , Wessely Oliver , Marcusson Eric G. , Ivan Cristina , Calin George A. , Alahari Suresh K.
Published: April 2023

PDF file - 58K
Supplementary Table S3 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Table S3 PDF file - 149K, List of transcription factors used in this analysis
Supplementary Table 1 from Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals
Authors: Miyabayashi Koji , Ijichi Hideaki , Mohri Dai , Tada Motohisa , Yamamoto Keisuke , Asaoka Yoshinari , Ikenoue Tsuneo , Tateishi Keisuke , Nakai Yousuke , Isayama Hiroyuki , Morishita Yasuyuki , Omata Masao , Moses Harold L. , Koike Kazuhiko
Published: April 2023

Supplementary Table 1 PDF file - 108K, Adding erlotinib to gemcitabine synergistically inhibited the growth of mouse and human PDAC cells
Supplementary Figure S4 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S4 PDF file - 1138K, Cell viability and corresponding mRNA reduction of eight candidate genes selected for further experimentation
Supplementary Figure S3 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S3 PDF file - 2243K, RNAi analysis and measurement of cell viability of amplified and overexpressed chromosome 13 candidate genes
Supplementary Figure S11 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Figure S11 PDF file - 415K, Overexpression of LNX2 in colorectal carcinoma compared to normal mucosa
Supplementary Methods from Deficiency of Phospholipase A2 Group 7 Decreases Intestinal Polyposis and Colon Tumorigenesis in ApcMin/+ Mice
Authors: Xu Changxin , Reichert Ethan C. , Nakano Tomoyuki , Lohse Mariah , Gardner Alison A. , Revelo Mónica P. , Topham Matthew K. , Stafforini Diana M.
Published: April 2023

PDF file - 92K, Supplementary methodology, including materials utilized, siRNA sequences, a description of immunoblot and immunohistochemical procedures, and statistical considerations.