bluuebunny/crossref_metadata_2025 huggingface dataset:
PENDAMPINGAN BIMBINGAN KONSELING UNTUK ANAK USIA DINI BAGI GURU YAYASAN MUSLIMAT NU BRAJA SELEBAH
Authors: Trismahwati Dewi , Yacub Jamiluddin
Published: August 2024

Masa keemasan merupakan masa dimana Anak Usia Dini dapat tumbuh dan berkembang secara optimal. Salah satu caranya adalah dengan pemberian stimulus yang tepat. PAUD (Pendidikan Anak Usia Dini) hadir sebagai lembaga pendidikan formal yang memiliki peran utama selain keluarga dalam mengawal pertumbuhan dan perkembangan anak. Pengawasan tersebut dapat terwujud dalam salah satu layanan di PAUD yang memiliki fungsi pendidikan dan pembimbingan Anak Usia Dini, yaitu layanan bimbingan dan konseling. Keberhasilan fungsi dan peran layanan bimbingan dan konseling PAUD tidak lepas dari kompetensi dan keterampilan yang dimiliki oleh guru atau konselor. Tujuan pengabdian ini adalah memberikan pendampingan kepada guru dalam melakukan perannya sebagai konselor layanan bimbingan dan konseling, yaitu dengan meningkatkan pengetahuan dan wawasan. Metode yang digunakan yaitu 1) tahap perencanaan berupa wawancara dan observasi, 2) tahap pelaksanaan berupa ceramah, tanya jawab dan praktik, 3) tahap evaluasi berupa pendampingan berkelanjutan melalui grup whatsapp. Kegiatan ini diikuti oleh 8 guru TK Muslimat NU Braja Selebah. Hasil dari kegiatan ini adalah guru atau konselor semakin memahami teori dasar dan praktik pemberian bimbingan dan konseling untuk Anak Usia Dini.
PENDAMPINGAN OTOMASI PERPUSTAKAAN SEKOLAH DI KECAMATAN WAY JEPARA – LAMPUNG TIMUR TAHUN 2021
Authors: Kholijah Siti , Kurniasih Apri
Published: August 2024

Senayan Library Management System (SLiMS) merupakan aplikasi Open Source yang belum banyak diketahui oleh pengelola Perpustakaan Sekolah pada umumnya. SD Alam Azzahra dan SMK YPI Way Jepara sebagai salah satu lembaga penyelenggara pendidikan di Lampung Timur merupakan salah satu sekolah yang belum mengetahui pemanfaatan software tersebut. Hal ini dapat dilihat dari perangkat komputer yang tersedia di perpustakaan sekolah yang masih belum difungsikan sebagai perangkat utama dalam aktifitas pengelolaan perpustakaan. Ini disebabkan karena minimnya informasi yang didapat oleh pihak sekolah terkait pelaksanaan pengelolaan perpustakaan yang ideal. Hasil dan luaran dari PKM ini adalah meningkatnya pemahaman dan kemampuan yang dimiliki oleh pengelola perpustakaan SD Alam Azzahra dan SMK YPI Way Jepara dalam aktifitas pengadministrasian perpustakaan berbasis SLiMS. Tim Pengabdian Kepada Masyarakat (PKM) menyediakan software yang dimaksud kepada pihak sekolah, melakukan kegiatan sosialisasi dan pelatihan penggunaan software SLiMS kepada pengelola perpustakaan dan meberikan pendampingan dalam implementasi SLiMS.
Levels and Predictors of Unsuppressed Viremia among People Living with HIV on ART in an Urban Population of North-Central Nigeria: A Retrospective Cross-sectional Study
Authors: Onubi Jeremiah , A. Adeola Oluwagbenga , Eseigbe Patricia , Elisha Adesegun , Chima Harrison Christian , Nwankwo Chizoba , Chima Anyuku A.G.
Published: August 2024

Achieving viral suppression is crucial for the effective management of HIV. We investigated the prevalence and predictors of unsuppressed viremia among adults living with HIV (PLHIV) on antiretroviral therapy (ART) in the urban city of Jos, Plateau State, North-central Nigeria. A cross-sectional study was conducted with 2,748 PLHIV, comprising 1,902 females (69.2%) and 846 males (30.8%). The majority (71.0%) were aged 36-55 years. Most participants (88.1%) were on the first-line ART regimen tenofovir disoproxil fumarate-lamivudine-dolutegravir (TDF+3TC+DTG), with 6.0% on second-line regimens. The prevalence of unsuppressed viremia (viral load >1,000 copies/mL) was assessed, and predictors were identified using chi-square tests and logistic regression analyses. Overall prevalence of unsuppressed viremia was 4.0% (110 participants), with higher proportions among males (5.6%) compared to females (3.3%) and among those aged 18-35 years (7.9%) compared to other age groups. PLHIV on first-line TDF+3TC+DTG ART had the lowest level of unsuppressed viremia (2.6%). Chi-square tests revealed significant associations between unsuppressed viremia and gender (χ2=7.67, p=0.01), age group (χ2=13.19, p=0.01), and ART regimen (χ2=110.97, p=0.0001). Multivariate logistic regression identified males (AOR=1.69; 95% CI: 1.12-2.56), younger age groups (18-35 years: AOR=12.96; 95% CI: 2.12-79.09 and 36-45 years: AOR=12.84; 95% CI: 3.70-44.64), and non-TDF+3TC+DTG regimens as significant predictors of unsuppressed viremia. The study highlights the effectiveness of the TDF+3TC+DTG regimen and the need for targeted interventions to address disparities in viral suppression, particularly among males and younger individuals. These findings are crucial for optimizing HIV treatment strategies and improving health outcomes for PLHIV in urban areas of low-and-middle-income countries.
Assessing the Effect of Sustainability Reporting and Firm Value on the Consumer Goods Industry
Authors: Amoako Mr David , Attafuah, (MIoD) Dr. Edward Domina
Published: August 2024

This thesis investigates the relationship between sustainability reporting, firm value, and brand quality in the consumer goods industry. The study seeks to explore how sustainability reporting practices influence firm value and whether brand quality mediates this relationship. To achieve this objective, quantitative research methods, including regression analysis and structural equation modeling (SEM), will be employed to analyze data collected from a sample of consumer goods companies. The research will examine the direct and indirect effects of sustainability reporting on firm value through brand quality. The theoretical framework of this study draws from the fields of sustainability reporting, brand management, and corporate finance. It is hypothesised that firms that engage in comprehensive sustainability reporting practices will experience enhanced brand quality, which in turn positively affects their financial performance and firm value. Using statistical techniques, the mediating role of brand quality in the relationship between sustainability reporting and firm value will be tested empirically. The sample for this study will consist of publicly listed consumer goods companies with available data on sustainability reporting, brand quality metrics, and financial performance. Data will be collected from annual reports, sustainability reports, and other relevant sources. The analysis will control for firm-specific variables such as size, profitability, and industry characteristics to isolate the effects of sustainability reporting and brand quality on firm value. The findings of this research are expected to contribute to the existing literature on sustainability reporting, firm performance, and brand management. The study will provide valuable insights for academics, practitioners, and policymakers interested in understanding the impact of sustainability reporting on firm value and the mechanisms through which sustainability initiatives can create value for consumer goods companies. Furthermore, the results of this study may have implications for corporate strategy and disclosure practices, particularly in industries where brand reputation and consumer perceptions play a significant role in driving competitive advantage and financial performance.
Resistance Across Borders: Belarusian Civic Activism in Exile under (Trans-)National Repression
Authors: Navumau Vasil , Matveieva Olga , Gorokhova Tetiana
Published: August 2024

The mass protests following the rigged 2020 presidential elections in Belarus led to unprecedented repression, resulting in the liquidation of over 1,600 NGOs, the imprisonment of hundreds of activists, and the displacement of thousands. After relocating, these activists continued to mobilize resources and use digital platforms to sustain and expand their support networks across borders. Urban activists played a pivotal role in this transformation, though they acutely felt the challenges of relocation due to their dependence on physical urban spaces and their ties to support networks and governmental bodies. This paper investigates the challenges faced by urban activists, post-relocation, as well as their resource mobilization strategies, utilizing surveys of 47 Belarusian NGOs and conducting 20 in-depth semi-structured interviews with urban development experts. It contributes to the understanding of civic activism in exile, emphasizing the strategic use of resources to reorganize activity and resist transnational repression of authoritarian regimes.
Congenital Nasal Pyriform Aperture Stenosis as a Rare Cause of Cyclical Cyanosis
Authors: Wan Ali Wan Nur Amirah Syahirah , Abdul Mutalib Nor Shahida , Aziz Azliana , Mohamad Hazama , Mohamad Irfan
Published: August 2024

Congenital nasal pyriform aperture stenosis (CNPAS) is a rare condition affecting the upper airway system. Unlike choanal atresia, the symptom if any, can be insignificant or appear delayed. We report a case of a 3-month-old baby girl who had history of sudden brief episodes of cyanosis and desaturation during sleep and relieved upon awakening and crying. It was associated with intermittent stertor and required oxygen supplementation. The airway symptom worsened with rhinorrhea and nasal blockage, which required re-admission. The inability to introduce a suction catheter size 6 French and pediatric flexible scope size 2.2mm into bilateral nostrils was diagnostic.
Contemplating Screening for Protein S Deficiency: To Screen or Not?
Authors: Ong Jia Cheng , Mohamad Norsarwany
Published: August 2024

Protein S (PS) deficiency is a thrombophilia disorder due to the reduced activity of protein S which regulates coagulation function leading to venous thromboembolism (VTE) event. It is an autosomal dominant disorder whereby it can be heterozygous or homozygous. A positive family history of protein S deficiency is a significant risk factor for developing thromboembolism. We report a case of an infant born to a mother with suspected protein S deficiency. The dilemma is whether we should screen this infant for protein S deficiency. His baseline coagulation profile was normal according to age and had no thrombotic event throughout his neonatal period.
Bioformulation: A New Frontier in Horticulture for Eco-Friendly Crop Management
Authors:   Department of Fruit Science, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur, Uttar Pradesh, 208002, India, Singh Budhesh Pratap ,   Department of Vegetable Science, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur, 208002, India, Sachan Kushal ,   Department of Soil Science and Agricultural Chemistry, C. S. Azad University of Agriculture and Technology Kanpur U.P -208002, India
Published: August 2024

Bioformulation represents a groundbreaking approach in horticulture, heralding a new era of eco-friendly crop management. By harnessing the power of naturally occurring organisms and compounds, bioformulation offers sustainable alternatives to conventional agricultural practices. This innovative technique involves the formulation of beneficial microbes, biocontrol agents, and organic substances into products that enhance plant growth, protect against diseases, and improve soil health. Through meticulous research and development, bioformulation has emerged as a potent tool for reducing the reliance on synthetic chemicals and minimizing environmental impact. This abstract delves into the transformative potential of bioformulation in revolutionizing horticulture, emphasizing its role in promoting healthier plants, enhancing agricultural sustainability, and contributing to a greener future for generations to come.
Study on biocontrol aspect of potential Alcaligenes faecalis against Fusarium sp.,Concept and Approach
Authors:   Department of Industrial Microbiology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur- 273009, Uttar Pradesh, India, Singh Pooja ,   Department of Botany, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur- 273009, U.P, India
Published: August 2024

The world is dealing with vivid pollutions which lead to the degradation of resources and human health. In soil, the yield of crops is enhanced by the rampant use of chemical pesticides and fertilizers. The fungicides are applied on a large scale on almost all crops to control fungal infection which is the primary cause of crop productivity loss globally. The chemical fungicides are nevertheless causing great harm to soil quality and human health as many fungal pathogens are resistant to these chemical fungicides and all applied in bulk. There is a huge need for the substitution of such fungicides by natural components. The work is just an attempt in this aspect only to glorify Alcaligenes faecalis as a natural substitute for chemical fungicides as its bio- remediating aspect is explored earlier. The least explored association of Alcaligenes faecalis with Fusarium sp. which could be a futuristic fungicide is represented. Fusarium sp. (mainly Fusarium oxysporum and Fusarium incarnatum) are quite pathogenic causing great loss to various plants and crops across the globe. They are altogether responsible for wilt, leaf spot and root rot diseases. Alcaligenes faecalis as a potent biocontrol agent is introduced here as this bacterium has plant growth- promoting features too. So, Alcaligenes faecalis could become a natural, futuristic and biological fungicide and fertilizer. The large-scale bioinoculant production with its specific carrier molecules needs to be explored.
Tree families and physical structureacross an elevational gradient in a Southern AndeanCloud forest in Ecuador
Authors:   Department of Biology, Oklahoma State University, Oklahoma City, OK 73107, USA., Myster R. W.
Published: August 2024

Because the elevational gradient of the Andes is a fundamental correlate of the structure, function, and dynamics of its Cloud forest, I sampled treespecies, families and physical structure across an 1100 m elevational gradient – at 100 m intervals from 1900 m to 2800 m – in an Andean Cloud forest close to Loja in Southern Ecuador. I found (1) the species Clusia sp., Nectandra membrenacea and Miconia puncta, andthe families Clusiaceae, Lauraceae, Melastomataceae,and Rubiaceae, were most common with Annonaceae, Cyatheaceae, Hypericaceae, Malvaceae and Solanaceae least common and (2) skewed unimodal curves best fit the species and symmetric unimodal (Gaussian) curves best fit the families.I also found (1) totalstem density increased with elevation (772/ha – 984/ha) but not monotonically with the smallest stem size always the most common and (2) linear curves best fit physical structure. Iconclude that while both tree species and tree families were distributed individualistically across this Andean elevational gradient, with two families showing a peak at mid-elevations,stem density increased with elevation as stem sizedecreasedwhich lead to several parameters (e.g., basal area, above-ground biomass) being unchanged while others (e.g., richness, diversity) were always low.
Green Human Resources Management Practices and Tertiary Institution Productivity in South West Nigeria
Authors: Ezekiel, Evelyn Ilamosi.  , Bako, Yusuf Adebola  , Olopade Oluwaseun John
Published: August 2024

Abstract: Inadequate Implementation of Green human resources Practices in tertiary institutions in South West Nigeria has made the higher institution of learning to face challenges in integrating environmental conservatives policy in their operations. The study therefore examined the effect of green human resources practices on organizational productivity of tertiary institutions in Nigeria. The study adopted a cross- sectional survey research design with the aid of structured questionnaire. The population for the study are the employees of the all the six (6) Federal polytechnics in South Nigeria, totaling 5028. From this population, an aggregate sample size of 371 participants were selected using Taro Yamane sample size calculator where proportional allocation was used to select participants for inclusion per tertiary institution. Structural equation modeling using Smart-PLS 4.0 was used for data analysis; as results indicated that GIO ( , T-statistic = 3.512, p < 0.05), GRCM ( , T-statistic = 8.385, p < 0.05), and GRS ( , T-statistic = 4.711, p < 0.05) have significant positive effects on organizational productivity. This highlights the importance of these green HR practices in enhancing productivity in the selected tertiary institutions in Southwest Nigeria. The study concluded that green human resources management practices is crucial in achieving optimal organizational productivity of the federal polytechnics in South West Nigeria. The study therefore recommended that the management of the federal Polytechnics in South West Nigeria should use environmental conservative employer branding to attract, select applicants and retain employees who have green orientation through a well-defined and circulated environmental sustainability human resources policy.
Equilibrium Solution of Two – Dimensional Non-Homogeneous Equations in the Theory of Elastic Mixtures
Authors: Udoh, Paul J.  , Udoh, Inemesit J.
Published: August 2024

Abstract: The problem of plane elasticity for a doubly connected body with inner and outer boundaries in a regular polygonal form with common centre and parallel sides has been studied. The sides of the polygon were exposed to external forces. The nature of the force term was determined by application of complex variable theory. Kolosov’s method of solution was applied to obtain the biharmonic equation of the forcing term. The forces on the particle were studied under 2-dimensions from which the compatibility and equilibrium equations were derived. The compatibility and equilibrium equations were used to derive the force – stress relations. The results shows that there is a significant relationship between the angle of the force term on the plane of the particle and the stress state of the particle, which is in conformity with existing experimental results.
Evaluation of Serum Levels of Carbon Monoxide and Lead in Smokers in Nnewi Metropolis
Authors: Nosakhare Osakue Omoyemwen , Alfred Ehiaghe Friday , Augustine Ihim Chinedu , Collins Obi Uche , Wendy Okonkwo Chidiebube , Ejike Onah Christian , Chinedum Onyenekwe Charles , Nosakhare Osakue Eric , Chidiadi Njoku Maryann , Amara Joy Onyenekwe
Published: August 2024

Background: Cigarette smoking is a major source of exposure to carbon monoxide (CO). CO is a colourless, odourless gas that displaces oxygen in the blood, which can lead to a variety of health problems, including heart disease, stroke, peripheral vascular disease, cancer, reduced cognitive function, premature birth, and low birth weight. This study was conducted to evaluate the levels of Carbon monoxide (CO) in active smokers in Nnewi Metropolis. Methods: This was a cross-sectional study involving 100 participants comprising of 50 smokers and 50 non-smokers, all within the age range of 18-45 years. The participants were recruited by simple random sampling technique. Recruited smokers were grouped based on duration of smoking into those who had smoked for less than 2 years (n = 20), those who had smoked for 2 years to 5 years (n = 19) and those who had smoked for more than 5 years (n = 11). The participants were also grouped based on type of substance smoked into those who smoke cigarette (n-12) alone, those who smoked weed alone (n=20) and those who smoked other substances aside from cigarette and weed (n=18). Carbon monoxide levels was determined by spectrophotometric measurement of caboxyhaemoglobin as it has been validated various researches as valuable for measurement of exposure to carbon monoxide. Independent sample test and Analysis of variance (ANOVA) were used for statistical analysis of data. Results: The mean ± SD carboxyhaemoglobin level (4.45 ± 0.86 %) smokers was significantly higher than in non-smokers (carboxyhaemoglobin 1.61 ± 0.21 %, p<0.001). There were no differences in mean levels of carboxyhaemoglobin between individuals who smoke cigarette compared to individuals who smoke weed (p>0.05), individuals who smoked cigarette compared to individuals who smoke other substances (p>0.05) and individuals who smoked weed compared to individuals who smoke other substances (p>0.05). Carboxyhaemoglobin was higher in individuals who have been smoking for more two years and above than in individuals who have been smoking for two years and above (p>0.05). Discussion And Conclusion: This study observed that carbon monoxide level was higher in active smokers than in non-smokers. This study also observed that carbon monoxide was not dependent on the type of substance smoked. However, duration smoking for less than 2years was characterised by lower COHB% compared with duration of more than 2 years smoking. Although the levels of caaboxyhaemoglobin observed in smoker was below WHO approved permissible level of carbon monoxide in active smokers, the outcome of this study further buttresses the fact that smoking predisposes individuals to carbon monoxide toxicity.
The Value of Naples Prognostic Score in Predicting Ischemia on Myocardial Perfusion Scintigraphy
Authors: Unkun Tuba , Fidan Serdar , Türkday Derebey Sevim , Güvendi Şengör Büşra , Aytürk Mehmet , Sarı Münevver , Efe Süleyman Çağan , Alıcı Gökhan , Özkan Birol , Karagöz Ali
Published: August 2024

Objectives: Naples prognostic score (NPS) is a recently established score that measures inflammation and nutritional conditions. This score includes lymphocyte-to-monocyte ratio, neutrophil-to-lymphocyte ratio, total cholesterol levels, and serum albumin levels. Initial studies have shown that the NPS score has more prognostic value than other inflammatory parameters in some cancer diseases. Recently, the association of the NPS score with various cardiovascular diseases has started to be evaluated. The association between ischemia in myocardial perfusion scanning and the Naples score has not yet been investigated. In this study, we evaluated if the NPS may help predict ischemia in myocardial perfusion scanning.

Methods: This study included a total of 110 patients. All patients underwent myocardial perfusion scintigraphy (MPS) at the nuclear medicine department, with dipyridamole or adenosine administered as the pharmaceutical stressor. The subjects were divided into two groups according to the presence or absence of ischemia on gated single-photon emission computed tomography (SPECT) MPI. Laboratory values within the past month before MPS were obtained from digital records for both groups. The NPS was calculated for each group. Laboratory values and NPSs of the groups were compared.

Results: All individuals in the trial had gated SPECT MPI. The average age of individuals was 59.8±11.1 years, with 62 patients (56%) being male. Subjects were divided into two groups according to the presence or absence of ischemia on gated SPECT MPI. Table 1 displays the demographics of the whole study population. Based on the laboratory data (Table 2), there was no significant difference in the demographic features of the groups. The ischemia group had significantly higher levels of white blood cell count (cells/ μL), neutrophil count (cells/µL), hemoglobin (g/dL), CRP (mg/L), and NPS (8.6±2.2, 7.7±1.9, p=0.040; 5.0±2.1, 4.1±1.3, p=0.014; 12.6±1.7, 13.4±1.8, p=0.025; 8.2±2.0, 7.9±2.0, p=0.004; 2.6±1.0, 1.5). Other laboratory results did not differ across the groups.

Conclusion: Our findings indicated an association between NPS and the detection of ischemia in MPS. NPS is an independent variable for diagnosing myocardial ischemia in stable coronary artery disease patients.
The Effect of Perceived Stress on Quality of Life in Patients with Myocardial Infarction
Authors: Çoban İlkay , Yürügen Birsen
Published: August 2024

Objectives: Myocardial infarction (MI) is a common heart disease with a high mortality rate. In patients with MI, factors such as social isolation, the presence of a previous MI, and the presence of diabetes mellitus in some patients can create stress in the patient. Perceived stress after MI may lead to an increase in the frequency of hospitalization, frequent cardiac problems, and difficulty in adapting to secondary prevention programs. Therefore, it is important to know the relationship between perceived stress and quality of life. This study aimed to determine the effect of perceived stress on quality of life in patients with MI.

Methods: The population of this descriptive and correlational study consisted of all patients diagnosed with MI (n=506) who applied to the adult outpatient clinic of a Hospital in Istanbul between January and June 2021. The sample of the study consisted of 300 patients who came to the polyclinic for examination at the time of the study, were over 18 years old, were diagnosed with MI, did not have any communication problems, and did not receive psychiatric treatment and agreed to participate in the study. Research data were collected using the survey technique, Perceived Stress Scale-14 (PSS-14), and TR MI Dimensional Assessment Scale.

Results: A moderate positive significant relationship was found between the PSS-14 and the TR MI Dimensional Assessment Scale (r=0.656; p<0.01). There was a negative significant relationship between the perceived stress level of patients diagnosed with MI and their quality of life levels, and as the patient’s quality of life increased, their perceived stress level decreased. 42.9% of the patients’ quality of life levels were affected by their perceived stress level.

Conclusion: In light of the data obtained from the study, it was determined that perceived stress had a negative impact on the quality of life in patients with MI, and as perceived stress increased, the patient’s quality of life decreased.
Pengembangan Soal Numerasi Berbasis Wordwall Pada Konten Aljabar
Authors: Fadhilah Lailafi
Published: August 2024

Penelitian ini bertujuan pada pengembangan soal numerasi berbasis wordwall pada konten aljabar. Numerasi merupakan salah satu ketentuan dalam kurikulum merdeka yang saat ini sudah banyak diterapkan pada sekolah-sekolah. Kemampuan siswa dalam menyelesaikan soal numerasi dapat diketahui dengan menggunakan alat evaluasi. Wordwall merupakan salah satu bentuk inovasi yang bisa diguakan sebagai alat evaluasi. Wordwall sendiri dapat diakses melalui laptop maupun smartphone. Penelitian ini menggunakan jenis penelitian pengembangan dengan model Plomp. Penelitian ini menggunakan 33 siswa sebagai subjek penelitian. Hasil penelitian pada pengembangan ini yaitu berupa produk soal numerasi berbasis wordwall yang teruji sangat valid (97%), sangat praktis (86,29%) dan efektif (88%). Produk yang dihasilkan berupa 20 butir soal numerasi.
IMPACTO DA TERAPIA HORMONAL NA QUALIDADE DE VIDA DE MULHERES NA PÓS-MENOPAUSA: UMA REVISÃO LONGITUDINAL
Authors: Fernandes Isadora Marçal Barbosa , Medeiros Alexandra Candido , Milheiro Gustavo Ramos , Rezende Amanda Oliveira de , Dias Maria Fernanda Figueiredo Lanza , Franco Gabriel Bordalí , Nardelli Lucas Jorge , Barreto Sandrieler Nunes , Faria Ivan Aurélio Fortuna Kalil de , Faria Anna Beatriz Inácio Fortuna Kalil de
Published: August 2024

A terapia hormonal (TH) tem sido amplamente utilizada para mitigar os sintomas associados à menopausa, impactando significativamente a qualidade de vida das mulheres na pós-menopausa. Esta revisão longitudinal avaliou os efeitos da TH ao longo do tempo, considerando uma ampla gama de estudos que incluíram ensaios clínicos, estudos de coorte e revisões sistemáticas. Os resultados indicam que a TH oferece benefícios substanciais na redução de sintomas vasomotores, na melhoria da saúde mental e na função sexual das mulheres na pós-menopausa. No entanto, esses benefícios tendem a diminuir ao longo do tempo, enquanto os riscos, como o aumento da incidência de câncer de mama e eventos cardiovasculares, tornam-se mais pronunciados com o uso prolongado. A revisão destaca a necessidade de uma abordagem individualizada e uma reavaliação contínua dos riscos e benefícios da TH, garantindo que a qualidade de vida das pacientes seja otimizada. Este estudo reforça a importância de decisões clínicas informadas e centradas na paciente, com base em uma análise equilibrada dos benefícios e potenciais efeitos adversos da TH.
Dual-tracer constraints on the Inverse-Gaussian Transit-time distribution improve the estimation of watermass ages and their temporal trends in the tropical thermocline
Authors: Guo Haichao , Koeve Wolfgang , Oschlies Andreas , He Yan-Chun , Kemena Tronje Peer , Gerke Lennart , Kriest Iris
Published: August 2024

Abstract. Quantifying the mean state and temporal change of seawater age is crucial for understanding the role of ocean circulation and its change in the climate system. One commonly used technique to estimate the water age is the Inverse Gaussian Transit Time Distribution method (IG-TTD), which applies measurements of transient abiotic tracers like chlorofluorocarbon 12 (CFC-12). Here we use an Earth system model to evaluate how accurately the IG-TTD method infers the mean state and temporal change of true water age from 1981 to 2015 in the tropical thermocline (on isopycnal layer σ0=25.5 kg ⋅ m-3). To this end, we compared the mean age of IG-TTD (Γ) derived from simulated CFC-12 with the model "truth", the simulated ideal age. Results show that Γ underestimates the ideal age of 46.0 years by up to 50 %. We suggest that this discrepancy can be attributed to imperfect assumptions about the shapes of transit-time distribution of water parcels in the tropics and the short atmospheric history of CFC-12. As for the temporal change of seawater age, when only one transient tracer (CFC-12) is available, Γ might be an unreliable indicator and may even be of opposite sign to trends of it due to uncertainties of mixing ratio. The disparity between Γ and ideal age temporal trends can be significantly reduced by incorporating an additional abiotic tracer with a different temporal evolution, which we show by constraining Γ with sulfur hexafluoride (SF6) in addition to CFC-12.
Telerehabilitation Guidelines for Patients with Breast Cancer (Ukrainian Language Edition)
Authors: Vladymyrov Oleksandr A. , Semykopna Tetiana V. , Vakulenko Dmytro V. , Syvak Oksana V. , Budnyk Mykola M.
Published: August 2024

The document covers current advancements in telerehabilitation, including regulatory frameworks, clinical aspects of postmastectomy pain syndrome, and the role of the International Classification of Functioning, Disability and Health in managing patients with breast cancer. It details the Telerehabilitation Platform, describing its structural and functional components, including software modules and administrative subsystems. The guidelines also outline methods for evaluating telerehabilitation effectiveness and discuss patient-centered telerehabilitation programs for various stages, from preoperative to long-term care. Nine appendices provide additional resources such as questionnaires, physical therapy programs, and equipment requirements.
Risonhas crônicas de Emir Macedo Nogueira
Authors: Uno Maiara Keiko Uno
Published: August 2024

Analisam-se quatro crônicas da autoria de Emir Macedo Nogueira que mostram a mudança, ao longo dos anos, de palavras e expressões que, à época da publicação, eram comuns ao linguajar cotidiano. As crônicas, denominadas “A semântica e a relatividade dos palavrões”, “A revolução de 9 de julho e simplificação ortográfica”, “Colorida” e “‘Mais melhor’” e “‘o salsicha’” são exemplos de vivacidade da constante mudança imposta pelos usos da Língua Portuguesa. Busca-se, assim, por meio de textos curtos e bem humorados, trazer a reflexão e a comparação entre passado e presente.
Desenvolvimento Emocional no Primeiro Ano do Ensino Fundamental: Proposta de Material Didático para Fomentar a Identificação e Regulação das Emoções
Authors: Zoppo Beatriz Maria , Rossetin Ana Paula Dalagassa , Gonçalves Laura Gomes
Published: August 2024

Desenvolvimento Emocional no Primeiro Ano do Ensino Fundamental: Proposta de Material Didático para Fomentar a Identificação e Regulação das Emoções
Jogos cooperativos: uma abordagem para alfabetizar alunos no 2° ano do ensino fundamental
Authors: Venancio Amanda Rocha Moreira , Silva Izabel Carolina de Souza , Sagatio Sandra Guimarães
Published: August 2024

Jogos cooperativos: uma abordagem para alfabetizar alunos no 2° ano do ensino fundamental
A relação entre trabalho e educação: impactos na qualidade de vida
Authors: Carneiro Danilo , Santos Isaac dos , Bernz Mariana Rogoski
Published: August 2024

A relação entre trabalho e educação: impactos na qualidade de vida
The pharmaceutical patent process: National Health Surveillance Agency and National Institute of Industrial Property act differently in the process
Authors: De Souza Leiraud Hilkner , Tahara Amaral Creusa Sayuri
Published: August 2024

The National Institute of Industrial Property (INPI) is the government body responsible for granting patents in the national territory; in the case of medicines, they need to be registered with the National Health Surveillance Agency (ANVISA) in order to be marketed. There was a divergence in legal interpretation (of Art. 229-C of the IPL) which caused damage to entrepreneurs, laboratories and the community in general, as there was no express provision as to whether ANVISA's opinion would be binding on the INPI's decision on patent issues. The aim of this research was to analyze this problem, raising its main points and demonstrating how dangerous and damaging bureaucracy and inefficient and obscure normative acts that give rise to dubious interpretation can be, based on the application of hermeneutic and dialectical methods. In 2021, the Superior Court of Justice (STJ), in Special Appeal n. 1543826, held that ANVISA's opinion would be a valid prerequisite for granting patents for pharmaceutical products or processes. It was found that the STJ decision increased ANVISA's "powers", but with the repeal of Art. 229-C of the IPL, the dilemma was extinguished and the competencies of each body re-established. It is therefore of the utmost importance to fill legal gaps and issue clear and specific laws so as not to leave room for harmful interpretations, guaranteeing original competences and legal certainty.
Managing Knowledge for Pharma and Biotech Innovation
Authors: Cavicchioli Sophia , Miziara Leonardo , Pinheiro Camila , Barud Hernane , Coury Cibele
Published: August 2024

Knowledge Management (KM) involves a deliberate and systematic organization of people, processes, structure, and technology with the main objective of creating value for innovation from the reuse of data and information. Although there are several models for KM in various types of organizations, there is nothing concrete to integrate the knowledge generated in collaborative University-Industry projects. This work aimed to gather elements for the creation of a sustainable model of effective articulation in this scenario. It is a strategic action that can bring benefits of intellectual, economic, and social impact. This research used different instruments: systematic mapping, questionnaires, and experience reports. The mapping highlighted the need to consider the following aspects for the development of KM models: collaborative/competitive arrangements, tacit/explicit knowledge managers and change screening. The questionnaire and report demonstrated that the challenges go beyond aspects such as data organization. They must prioritize the social aspect of knowledge sharing, using safe coordination to prevent misconduct.
Sosialisasi Penggunaan Teknologi Produksi dan Pemasaran Terasi Berdaya Saing Nasional Pada Masyarakat Desa Kuala Penaga Aceh Tamiang
Authors: Agustinar  , Rafiza Zuliani  , Suryani Suyani
Published: August 2024

The process of making shrimp paste in the people of Kuala Peunaga Village still uses a manual process with very minimal output, unattractive packaging and the marketing process still uses traditional methods, namely direct marketing and mouth to mouth so that the production of shrimp paste in the village has not been touched by the outside community is a problem that drives the existence of socialization activities in the form of this service. This activity aims to provide educational knowledge about the importance of using modern technology in the shrimp paste production process and marketing through digital media by utilizing social media. The implementation method is by outreach to the community starting with observation, implementation of activities, monitoring and evaluation as well as ongoing support. After the implementation of this activity, the community is very enthusiastic about using modern technology and will promote their products by digitalization or through social media. This socialization is also highly expected by the community so that later there will be special training and assistance to develop the shrimp paste business of the people of Kuala Peunaga Village into a nationally competitive product.
Engelli Gençlerin Üniversite Eğitimi: Eğitime Dâhil Olma ve Sürdürme Bağlamında Kapsayıcı Eğitim
Authors: Eker Hülya
Published: August 2024

Gençler, dinamik ve değişime açık olmaları bağlamında toplumların geleceklerini belirleyen önemli bir gruptur. Gençlerin içinde daha spesifik bir grup olan engelli gençler ise dışlanma, istismar, ayrımcılık gibi pek çok sosyal risklerle karşılaşmaktadırlar. Bu gençlerin sosyal risklerle mücadele edebilmeleri için bağımsız yaşayabilmeleri önemlidir. Engelli olmayan gençlere kıyasla eğitim, ekonomi ve siyaset gibi toplumun pek çok alanında eşitsizliklere maruz kalmakta ve dolayısıyla temel insan hak ve özgürlüklerini kullanamamaktadırlar. Bu durum gençlerin bağımsız yaşayamamalarına dolayısıyla toplumda yoksul ve marjinal bir kesimi oluşturmalarına neden olabilmektedir. Bu durumu değiştirmede ise onların eğitim alanına dâhil olmaları önemli bir dönüm noktası olabilir. Engelli gençler için kapsayıcı eğitimi odağına alan bu çalışmanın temel amacı, ‘eğitim yaşamına dâhil ol(ama)ma’yı ve ‘eğitimi sürdür(eme)me’yi toplumsal yaşama dâhil olamama üzerinden tartışmaktır. Sonuç olarak kapsayıcı eğitim temelinde üniversite eğitimine katılım ve sürdürme; onların yaşamlarındaki sorunları daha görünür hale getirirken bağımsız yaşamalarına katkısı ise ‘gençlik’ ve ‘engellilik’ olgularının kesişimselliğinde olduğunu göstermektedir. Bireylerin farklılıklarının onların eşit yaşama hakkının önünde bir bariyer olmaması gerçekliğinden hareketle eğitime katılım bir insan hakkı meselesidir. Dolayısıyla kapsayıcı eğitim odağında onların üniversite eğitimine erişebilmeleri ve üniversiteden mezun olmaları istihdam fırsatlarının artması ve bireysel gelişimlerine katkı sunmasının yanında toplumsal yaşama dâhil olmaları açısından da önemlidir.
Biogas Production from Organic Materials
Authors: Safiullah Fetrat
Published: August 2024

Anaerobic digestion is a microbiologic process through which organic materials are broken down in oxygen absence and occurs in many environments. Now, biogas production is done in the reactors resistant to air penetration called digesters. A wide range of microorganisms is involved in the anaerobic process producing biogas and digestion as the final products. Biogas is a kind of flammable gas that contains methane, carbon dioxide, and a small amount of other rare elements and gases. Digestion of the decomposed materials rich in nutritional micros and macros plays the role of proper plant manure. Like other biofuels, biogas is also among the crucial priorities of energy and transportation policies made in Europe. In Europe, biogas is an inexpensive renewable energy source and neutral carbon dioxide that provides the field for processing and recycling many agricultural wastes and byproducts based on a sustainable and eco-friendly method. Biogas brings many socioeconomic advantages to society as a whole and also to investors.
Clinical and instrumental characteristics of coronary heart disease in association with type 2 diabetes mellitus
Authors: Gairatova I. B. , Rajabzoda M. E. , Asadov S. U.
Published: August 2024

Aim. To study the clinical and instrumental characteristics of the course of coronary heart disease (stable angina and post-infarction cardiosclerosis) in association with type 2 diabetes mellitus.Material and Methods. The study material consisted of 175 patients with coronary heart disease who met the selection criteria. All patients were divided into two groups according to the presence of diabetes mellitus: group I with type 2 diabetes mellitus (n=67) and group II without type 2 diabetes mellitus (n=108).Results. Patients with coronary heart disease associated with type 2 diabetes mellitus were older and accounted for 38.3% of the total group. Among the risk factors, arterial hypertension, hypercholesterolemia and obesity were the most important in the compared groups. An analysis of the course of coronary heart disease in the compared groups showed that non-anginal or other symptoms (shortness of breath) were more common in the diabetics. According to the results of echocardiography, the size of the atria (left and right) was larger in the group of patients with diabetes.Conclusions. The study showed that patients with coronary artery disease associated with type 2 diabetes were older, had a higher body mass index and cardiovascular risk factors.
Main factors of infant mortality in different regions of the Republic of Tajikistan
Authors: Abdusamatzoda Z. M. , Ikromov T. Sh. , Nabiev Z. N. , Ibodov Kh. I. , Shamsov B. A. , Yangibaeva B. U. , Mirzoev D. S. , Olimov D. A.
Published: August 2024

Purpose of the study. Identification of the main medical factors leading to the death of newborns.Material and method of research. To determine the structure of child mortality in the Republic of Tajikistan for 2017-2021 and 9 months of 2022 for selected cities and regions (the cities of Kulyab, Bokhtar, Penjikent, Istaravshan, Khujand, Kanibadam, Isfara, Vahdat)., Tursunzade and the districts of Bobojon Gafurov, Rudaki, Rasht, Fayzabad and Sh. Shahin) data on infant mortality were collected and entered into special questionnaires.To determine the structure of newborn mortality in the Republic of Tajikistan in 2017-2021 and the 9-month period of 2022 from selected cities and districts (the cities of Kulob, Bokhtar, Penjikent, Istaravshan, Khujand, Kanibadam, Isfara, Vahdat, Tursunzade and the districts of Bobojon Gafurov, Rudaki, Rasht, Faizabad and Sh. Shahin) data on newborn mortality were collected and entered into specially designed questionnaires. The study and evaluation used statistical, analytical and social criteria.Research results. Preliminary results of the analysis show that in most cases (61.5%) newborns died in the early neonatal period, a third of their losses in the early neonatal period most often died in the first 6 days after birth. The age of mothers of deceased newborns is mainly from 20 to 29 years (62.2%). This situation is almost the same in all regions of the republic.Conclusion. The analyzes indicate that mothers of deceased newborns had a low health index. During pregnancy, 47.2% of mothers experienced symptoms such as (preeclampsia, poliomyelitis, dehydration, eclampsia and preeclampsia, nephropathy, etc.). There are also discharges during labor such as preterm labor, meconium contamination of water, and cesarean section birth.
The Dual Impact of Foreign Capital: A Comprehensive Analysis of the Interplay between Foreign Direct Investment and Development Assistance Committee Initiatives in Ethiopia
Authors: Conable James E. , Onwuka Sampson C.
Published: August 2024

This study delves into the intricate dynamics of Ethiopia's economic landscape, examining the dual impact of foreign capital through a comprehensive analysis of Foreign Direct Investment (FDI) and Development Assistance Committee (DAC) initiatives. Over the period 1992-2012, a two-part empirical approach is employed, encompassing descriptive statistics and rigorous econometric modeling rooted in time series analysis. The nuanced relationship between foreign capital and economic growth in Ethiopia is unraveled, addressing challenges such as job displacement and potential exploitation, alongside positive outcomes like infrastructure development and increased service accessibility. The econometric analysis utilizes various models to explore the causal relationships between FDI, DAC, economic growth, and self-employment. Sensitivity analysis ensures the robustness of the models by unraveling multicollinearity, while stationarity tests guide appropriate treatment of non-stationary variables. Cointegration tests reveal potential long-term relationships among variables, with specific models suggesting cointegration, further substantiating the intertwined nature of FDI, DAC, and economic growth. Granger causality Wald tests scrutinize short-run equilibrium relationships, unveiling intriguing insights into the direct and indirect effects of FDI, DAC, and self-employment on economic growth. Robust diagnostic tests affirm the reliability of the models, indicating compliance with Ordinary Least Squares (OLS) conditions. In summary, our findings illuminate the dual impact of foreign capital on Ethiopia's economic trajectory, offering nuanced perspectives for policymakers. The study's comprehensive empirical foundation facilitates a deeper understanding of the complex interplay between FDI, DAC initiatives, and economic growth, paving the way for informed decision-making and future research endeavors.
The Effectiveness of KUR Sharia Products in PT. Pegadaian Talise Branch UPC Tawaeli in SME Development
Authors: Fadhilah Rifqah , Yunus Santi , Anam Haerul , Yunus Rita , Nasruddin M. Anwar
Published: August 2024

PT. Pegadaian as a financial institution has an important role in providing financing for sharia-based SME as part of an effort to support this real sector. This study aims to determine the impact and benefits of using KUR Syariah and analyze the effectiveness of KUR Syariah products in \ the development of SME. The research method used is descriptive qualitative. The results of this study indicate that KUR Syariah products are effective in supporting the development of SME and have a very positive impact on MSME actors, and the benefits obtained through financing are business development and easier financial management. This research found several aspects to improve the effectiveness of Sharia KUR products at PT. Pegadaian, including consistent goals, consistent time, quantity provisions, and credit provisions. The four ways to measure the effectiveness of KUR products are very precise based on the consistency of targets, quantity and time in applying or distributing KUR. Therefore, in this case it can be said that the Sharia KUR Products distributed by PT. Pegadaian UPC Tawaeli are considered effective and right on target.