bluuebunny/crossref_metadata_2025 huggingface dataset:
The difficult laparoscopic cholecystectomy: a bailout strategy
Authors: Chooklin S.M. , Chuklin S.S.
Published: January 2025

Laparoscopic cholecystectomy is one of the most frequent surgeries today. Given the procedure’s extensive adoption by surgeons across all skill levels, from novices to experts, it becomes imperative to develop guidelines to ensure its safety for patients. Since complexi-ty of surgeries differ in each person, ranging from simple to intricate cases involving a frozen Calot’s triangle, it is extremely important to perform laparoscopic surgery carefully to avert any potential harm. Given its global prevalence, even a 0.1 % complication rate translates to a significant figure. Therefore, practicing safe cholecystectomy is advocated strongly. This review presents modern approaches to laparoscopic cholecystectomy in difficult cases — bailout surgery — to prevent damage to the bile ducts and vessels. In particular, the features of subtotal cholecystectomy, fundus-first cholecystectomy, and infundibular dissection are considered.
Mental health of volunteers: origin of psychosomatic disorders in PTSD conditions
Authors: Kokun О.М. , Vizniuk І.М. , Paikush M.A. , Dolynnyi S.S. , Ordatii A.V. , Karimulin R.F.
Published: January 2025

Background. Numerous studies in various scientific areas deal with to the problem of mental health of Ukrainians: the theory and practice of psychological and pedagogical research, psychophysiological concepts and theories, a systematic approach in psychology, the psychophysiological aspect of the emotional background, as well as psychosomatic features of optimal personality functioning. Preservation of mental health has become a priority of the state policy of Ukraine to support the country’s stability and fighting capacity. The study of the impact of psychoemotional factors on the functional state of the body for the restoration and optimization of life support among volunteers who provide free psychological assistance and support the mental health of the population is relevant. The research was aimed at studying the origin of psychosomatic disorders in volunteers with post-traumatic stress disorder (PTSD), as well as determining the impact of these disorders on their mental health and psychosocial status. Materials and methods. The following psychodiagnostic tools were used: emotional burnout diagnosis method according to V. Boyko, NEWS questionnaire, PCL-5 questionnaire and post-traumatic growth questionnaire. According to the results of the study, it was found that emotional burnout in volunteers manifests itself in three phases: tension, resistance, and exhaustion according to indicators of a high level of stress and severe depression in respondents with signs of PTSD (23.9 %). Results. Mental disorders such as asthenic, anxiety-phobic, hysteroform and depressive syndromes are observed in all groups. Conclusions. The psychosomatic mechanism of the relationship between mental activity and behavior in PTSD includes the influence of a traumatic psycho-emotional factor that causes a constant feeling of danger, panic attacks or fear of repeating the situation, a feeling of hopelessness, low mood, apathy, loss of interest in usual activities, aggression, irritability, frequent conflicts and anger outbursts, feelings of detachment, social isolation, relationship problems and guilt for experiencing PTSD symptoms.
Effect of ranolazine on cardiac remodeling and pulmonary artery pressure in patients with acute pulmonary embolism
Authors: Tseluyko V.Y. , Kurinna M.V. , Kinoshenko Ye.I.
Published: January 2025

Background. The development of right ventricular (RV) dysfunction is the most significant predictor of in-hospital mortality and one of the most important factors affecting the short- and long-term prognosis of pulmonary embolism (PE). Therefore, the development of treatment regimens aimed at inhibiting the progression of RV dysfunction and the fastest possible restoration of its function, as well as preventing the development and progression of pulmonary hypertension, is an important area of reducing mortality in acute PE. One of the most promising drugs that can theoretically reduce both RV and pulmonary damage is ranolazine. The purpose of the study was to evaluate the feasibility and efficacy of prescribing ranolazine to patients with PE, focusing on its impact on echocardiographic parameters. Materials and methods. The study included 70 patients diagnosed with acute PE verified bу CT pulmonary artery angiogram performed on the first 1–2 days and after 8–10 days of treatment. Patients were divided into two groups: group 1 consisted of 29 people who received ranolazine at a dose of 500 mg twice daily starting from day 1–2 of standard treatment, for 1 month; group 2 included 49 patients who did not receive ranolazine. All patients underwent a standard general clinical examination with an assessment of risk factors for PE and early death according to the 2019 European Society of Cardiology guidelines, with subsequent statistical processing of the data. Results. When analyzing the dynamics of indicators in the groups, a statistically significant decrease was found in the size of the right atrium (p = 0.0009), RV (p = 0.046), mean pulmonary artery pressure (mPAP) (p = 0.027), pulmonary artery systolic pressure (sPAP) (p = 0.00004) in the group 1. In the group without ranolazine, there also was a decrease in the size of the right atrium (p = 0.002), mPAP (p = 0.009), and sPAP (p = 0.03), but with no effect on the size of the RV. When comparing the difference in parameters on day 1 and 8–10, i.e., the shift of the parameters during treatment, a statistically significant decrease in sPAP was obtained in the ranolazine group compared to the group without its use (p = 0.03). Conclusions. Adding ranolazine to standard therapy for pulmonary embolism reduces right ventricular and atrial remodeling, as well as pulmonary artery pressure.
Optimization of acute postoperative pain management in trauma and orthopedic patients
Authors: Shostak M.A. , Domoratskyi O.E.
Published: January 2025

Background. The modern approach to multimodal postoperative analgesia involves the administration of two or more analgesic agents that exert a polymodal effect on the pathogenetic mechanisms of pain. Nefopam hydrochloride can prevent opioid-induced hyperalgesia, relieve pain without respiratory depression and without affecting platelet aggregation, the state of the gastrointestinal mucosa and intestinal motility, which differentiates it from traditional non-opioid analgesics. Objective: to assess the impact of nefopam hydrochloride as a component of multimodal analgesia on pain intensity and stress response markers in trauma and orthopedic patients during postoperative pain management. Materials and methods. A prospective randomized open-label controlled clinical study was conducted in 120 patients (47 men, 73 women) aged 19 to 94 years (mean (M ± σ) of 55.97 ± 19.78 years) who underwent lower limb surgeries under spinal anesthesia. Patients were divided into two groups: the controls (n = 60) received standard multimodal analgesia (ketorolac, acetaminophen), while people in the main group (n = 60) additionally received 20 mg of nefopam hydrochloride intramuscularly 4 times per day. Pain intensity was evaluated using the Numeric Rating Scale, narcotic analgesic consumption, and cortisol levels in blood serum were assessed as well. Data analysis was performed using SPSS 20 (SPSS Inc.), version 21.0.0 for Windows. Results. It was found that the use of nefopam hydrochloride as a component of multimodal postoperative analgesia in patients undergoing trauma and orthopedic surgeries significantly reduces score on the Numeric Rating Scale: by 23.6 % during the first 6 hours after surgery (p < 0.001), and by 1.5, 2.3, and 3.6 times at 12, 18, and 24 hours postoperatively, respectively (p < 0.001). It was also associated with lower mean serum cortisol concentrations — 5.20 ± 4.43 vs. 8.51 ± 3.48 µg/dL in the control group 6 hours after surgery, and 2.08 ± 1.63 vs. 4.11 ± 1.70 µg/dL in 12 hours (p < 0.001). Additio-nally, it reduced the average cumulative morphine dose by 1.5 times during the first 24 hours postoperatively (p < 0.001). The opioid-reducing effect of multimodal analgesia with nefopam hydrochloride reached 61.7 %. Conclusions. Nefopam hydrochloride is an effective component of multimodal postoperative analgesia in trauma and orthopedic patients, improving the quality of postoperative pain management and reducing stress response intensity.
Impact of adding dexmedetomidine to various lidocaine concentrations in the interscalene brachial plexus block for upper limb surgery
Authors: Kolomachenko V.I. , Odynets I.Yu. , Havrykov O.Ye. , Kupin V.I.
Published: January 2025

Background. The interscalene brachial plexus block is widely used in orthopedic surgery for procedures on the proximal upper limb. However, the main concern remains the systemic toxicity of local anesthetics due to the use of their high concentrations. The purpose of the study was to investigate the effect of adding dexmedetomidine to lidocaine solutions of different concentrations in the interscalene brachial plexus block by examining the onset time and duration of motor block and analgesia. Materials and methods. The study included 75 patients who underwent elective upper limb surgery under interscalene brachial plexus block. They were divided into three groups (n = 25 each): control group I (L1%), group II (Dex L1%), and group III (Dex L0.5%). In group I, the brachial plexus block was performed using a 1% lidocaine solution with the addition of 50 mcg of epinephrine (1 : 400,000). In group II, 50 mcg of dexmedetomidine was added to the same solution, while group III (Dex L0.5%) used a 0.5% lidocaine solution combined with 50 mcg of dexmedetomidine. The duration of analgesia, motor function of the upper limb, hemodynamic changes, and side effects were assessed. Results. Preoperatively, the time of complete motor block onset (Me [25 %; 75 %]) in groups L1% and Dex L1% was 12.5 [10.0; 15.0] minutes, which was slightly shorter than in group Dex L0.5% (15.0 [15.0; 20.0] minutes; p = 0.06). The duration of complete motor block was longest in the Dex L1% group (330 [270; 440] minutes) compared to the Dex L0.5% group (305 [235; 348] minutes; p = 0.25) and the L1% group (185 [180; 255] minutes; p < 0.002). The duration of analgesia in the Dex L1% group (460 [330; 480] minutes) was significantly longer than in the Dex L0.5% group (305 [248; 425] minutes; p = 0.35) and the L1% group (270 [210; 333] minutes; p = 0.018), with no statistically significant difference between Dex L0.5% and L1% groups (p = 0.29). The heart rate was significantly reduced at the start and the end of surgery compared to baseline in the Dex L1% and Dex L0.5% groups. Systolic blood pressure was significantly reduced in all groups at all stages compared to baseline. Conclusions. The addition of dexmedetomidine prolongs both motor block and analgesia after interscalene brachial plexus block and allows the lidocaine concentration to be reduced to 0.5 % without compromising efficacy.
Exploring the Personal Experiences of Gay Men in the Five Pillars of the Philippine Criminal Justice System: Basis for Sustainable Extension Program
Authors: Capundan Jason B. , Belarmino Verna R.
Published: January 2025

This study examines the experiences of individuals within the Philippine Criminal Justice System (CJS), focusing on the Law Enforcement, Prosecution, Court, and Correctional Pillars, as well as challenges in reintegration. Participants reported mixed experiences with law enforcement, from humane treatment to dissatisfaction over unclear arrest procedures and alleged coercion. In the prosecution stage, accessibility and quality of legal representation varied, with some expressing appreciation for dedicated defense counsel, while others faced frustrations over prolonged periods without representation, contributing to disillusionment with the judicial process. The Court Pillar highlighted the issue of “justice delayed, justice denied,” as lengthy adjudication processes eroded trust in the judiciary. Within the Correctional Pillar, participants found conditions in the Capiz Rehabilitation Center to be more positive than anticipated, emphasizing the disciplined and respectful environment, strict anti-discrimination policies, and opportunities for personal growth through Technical Education and Skills Development Authority (TESDA) training and business ventures. However, overcrowding remained a significant concern. Reintegration into the community posed complex challenges, particularly for marginalized groups like the LGBTQ community, as societal stigma, limited employment opportunities, and the lasting impact of criminal records created systemic barriers to rebuilding their lives. Familial acceptance varied, further complicating transitions back into society. The study underscores the urgent need for reforms in arrest protocols, judicial efficiency, and correctional facility management. Additionally, fostering inclusive reintegration programs is crucial to addressing societal stigmas and supporting the successful transition of former Persons Deprived of Liberty (PDLs) into their communities.
Discursive Construction of CNPC’s Eco-friendly Image in Its Corporate Social Responsibility Report: A Legitimation Strategy Analysis
Authors: Ke Li
Published: January 2025

Corporate Social Responsibility (CSR) reports are important non-financial disclosures that provide insights into an enterprise’s commitment to social and environmental responsibilities. With the escalation of global environmental challenges, the focus on the disclosure of environmental responsibility information within CSR reports has intensified. As CNPC (China National Petroleum Corporation) is an environmentally sensitive corporation, this study investigates the legitimation strategies utilized in the environmental discourse of the CNPC’s English CSR Report of 2022, aiming to understand how CNPC constructs its legitimacy in sustainable development for international audience. The findings reveal that: (1) five principal legitimation strategies are employed—authorization, moralization, rationalization, mythopoesis, and altruism—with rationalization as the dominant strategy, representing 65.45% of all cases; (2) these strategies are grounded in diverse sources of legitimacy, such as collective authority and moral values, and are manifested through distinct lexical and syntactic choices; (3) these legitimation strategies constructs an authoritative and credible corporate eco-friendly image for CNPC. These findings contribute to the understanding of legitimation strategies in institutional environmental discourse and offer practical implications for enterprises aiming to enhance their international reputations in sustainable development and facilitate global expansion.
Diversidad en la educación en ciencias de la salud: argumento de lo distinto desde la variabilidad biológica
Authors: Botello Jaimes John Jairo , Sierra Guillermo Orlando , García Uribe John Camilo , Turriago Castañeda Angie Katherine , Arteaga Noriega Aníbal Vicente , Acevedo Oquendo Kely Johana
Published: January 2025

La discusión entre totalitarismo, dualismo y pluralismo es fundamental en el contexto educativo, especialmente en la formación de los profesionales de la salud. Debido a la interdisciplinariedad de estos conceptos, resulta necesario realizar una revisión narrativa de la literatura con el fin de analizar estudios recientes sobre diversidad genética, fenotípica, evolución, adaptación y educación en salud. En este sentido, el dualismo y el totalitarismo biologicista son enfoques que han influido negativamente en la educación en ciencias de la salud y en la sociedad. En contraste, el pluralismo reconoce la complejidad y la diversidad inherentes a los seres humanos. Este enfoque, además, se presenta como más adecuado para la educación en salud, promoviendo una comprensión más holística y adaptativa del aprendizaje en ciencias de la salud. La diversidad biológica y la pluralidad deben integrarse en la formación de los profesionales de la salud para fomentar la innovación y la adaptabilidad en los estudiantes.
Seismic Behavior of RC Multistorey Building Frame Structure with Different Plan Configuration
Authors: Kichande Rajendra Kumar
Published: January 2025

Today’s world facing some of the major problems causing by the nature. One of the major natural disasters is the
Earthquake. We never know the Direction of the attack and magnitude of the Earthquake, so it will be the challenge the science
and Technology. Past few years’ research done on the various issues of Earthquake. Now a Days people live in Multi-Story
Buildings such case when Earthquake knockout the populated areas it will be cause massive loss of Damage. Hence Earthquake
analysis get importance to Analysis the structure safe against the collapse and design the structure to safe against earthquake
occur during the life time of the structure. In this study model a G+11 Structure with square plan configuration in Staad Pro
and Analysis the Earthquake analysis of the Structure in seismic city Jabalpur which is located in seismic region III with Soft,
Hard and Medium soil with different seismic and structural parameters are used as per Indian Standard code. The analysis is
done by using STAAD Pro V8i software by Linear Static Analysis and compared the analysis of RC multistory building framed
structure in the term of Maximum Bending MomentStory wise Displacement
Application of factor analysis in the typology of agriculture in Serbia
Authors: Mihajlovic Ljiljana , Milincic Miroljub , Vukoicic Danijela , Petrovic Dragan
Published: January 2025

Factor analysis was used as a method for determining the types of agriculture
in Serbia, which resulted in the synthesised and comprehensive data
presented in the study. The subjectivity inherent in this method is
mitigated by relevant statistical facts that clearly guide the course of
factor analysis from the selection of parameters through rotation to the
final results. Agricultural types were identified based on the development
of specific factors and the administrative districts in which these factors
dominate compared to others. It should be noted that the results obtained in
this study cannot be considered relevant for further research, as the method
of factor analysis proved to be inadequate for the small num-ber of input
parameters and large spatial units such as administrative districts.
Determining the attractiveness of Serbian spas as a destination for wellness tourism
Authors: Belij-Radin Marija
Published: January 2025

Serbia has a long tradition in the development of spa tourism, which is
mainly intended for domestic tourists. As a result of current trends in
tourism, especially changes in tourist demand, destinations are also
changing. For many countries, the development of wellness tourism is an
important way to create a competitive advantage. The paper presents the
study of attractiveness characteristics of spa resorts in Serbia and then
ranks the spa resorts according to these factors. The model used in the
research consists of 24 factors (grouped into 6 groups) that influence the
attractiveness of spas as spa and wellness tourism destinations. The
research included twenty spas and the survey was conducted among experts in
the field of tourism. The most important factors influencing the
attractiveness of spas as spa and wellness tourism destinations are: The
attractiveness of the range of health and wellness treatments offered in
spas (0.349), the natural conditions and relaxing atmosphere of spas
(0.206) and price competitiveness (0.172).
Variability of climatic parameters in Tiefora, Burkina Faso: Scientific aspects and farmers' perceptions
Authors: Karambiri Bienvenue
Published: January 2025

The evolution of climatic parameters is of major importance for the
populations of the Sahel, and in particular Burkina Faso, whose agricultural
production is predominantly rain-fed. The aim of this study is to analyze
the variation in climatic parameters in the rural commune of Ti?fora in
Burkina Faso. Climatic data from 1991-2020 were collected from the National
Meteorological Agency (ANAM). In addition, individual questionnaire surveys
were carried out among 100 local people. The results show that from 1991 to
2020, 19 out of 30 years had rainfall in excess of 1000 mm. The area
experienced 16 years of rainfall surpluses, compared with 14 years of
rainfall deficits. In terms of temperature, the annual average rose from
27.08?C to 28.43?C from 1991 to 2020, a difference of 1.35?C. This indicates
a rise in temperature. Other climatic parameters (wind, humidity and ETP)
have also varied in the area, with an increase. The people of Ti?fora
perceive this rise in temperature and a fall in rainfall.
Assess the level of farmers' awareness regarding climate changes and its impacts on agriculture in Sétif province (north-east Algeria)
Authors: Nasri Samir , Belabbas Messaoud , Bouzid Hamza
Published: January 2025

The present study presents the phenomenon of climate changes through
discussing its impacts on agriculture productions in S?tif Province, which
is area of survey that located in the high plains of north-east Algeria. The
study focuses to evaluate the perception degree of peasants toward the
phenomenon via statistical analysis and discuss its futures challenges. It
is presumed that climate changes have a significant effect on agriculture
in the region; the water usage was increased in agriculture and the
expansion of saline areas has increase soil degradation. Still, the
vegetable and fruit crops reporting negative impacts living organisms are
experiencing imbalances in natural biodiversity. In other point, the
findings indicate that over half of the participants farmers (63.00%) have a
moderate level of knowledge about climate changes, while 18.04% have a high
level of knowledge. The status of the agriculture is in a critical condition
and the findings indicate a relative gap in understanding the climate
changes. Based on, some challenges have been revealed mainly: highlighting
the need for effective dissemination of agricultural recommendations to
improve farmers' knowledge that can support adaptation and mitigation toward
climate change effects. In parallel, the agriculture is in need of
continuous follow-up survey in the context of climate changes and
socio-economic aspect to assure the quality of life in rural area and
guaranteeing food security, where the environmental perspectives and
sustainable development should be considered in the future spatial planning.
Research on optimisation of rural tourism development path in Henan province
Authors: Dou Yingying , Dzhylkychieva Zhyldyz , Liang Zongzheng , Zhang Shuolei , Liang Liuke
Published: January 2025

Rural tourism, as an area of the tourism industry, demonstrates a steady
growth trend, highlighting the importance of implementing measures to
optimise it for the economic and socio-cultural prosperity of the regions.
The purpose of the study is to develop recommendations for optimising and
strengthening the promotion of rural tourism in Henan Province, which will
contribute to the sustainable development of the region, the preservation of
its cultural and natural legacy, and improving the living standards of the
local population. The following methods were used: descriptive, deductive,
generalisation and comparative analysis. The results of the study determined
that Henan Province, with its rich cultural legacy, historical monuments,
and nature, has essential prerequisites for the development of rural
tourism. The analysis of the current state of this tourism industry in the
region has identified the main problems and barriers faced by rural tourism
in the process of its improvement. Therewith, it was established that
investment difficulties, uneven infrastructure development, lack of
qualified personnel in the field of tourism and the lack of effective
programmes limit the potential of rural tourism in this region. Strategic
recommendations include fostering local investments, implementing digital
marketing strategies, and initiating community education programs in tourism
basics. Special attention needs to be paid to optimising approaches to the
development of this area at the local level to form a productive regional
strategy in the field of tourism, which will contribute to economic growth,
create new jobs, form appropriate marketing strategies for promoting tourism
products, support environmental initiatives, use digital technologies and
improve the well-being of the province in general. The practical importance
lies in the possibility of using the results of the study by researchers who
study the basics of rural tourism development and specialists in the tourism
industry.
Achieving high robust aluminum alloy annular laser directed energy deposition based on thermal field assistance system
Authors: Wan Le , Ren Bo , Yang Huihui , Shi Tuo , Tang Zijue , Zhang Rongwei
Published: January 2025

High thermal conductivity and large fluctuations in laser absorptivity with temperature make aluminum alloy prone to deformations, collapses, spheroidization, and other defects during directed energy deposition (DED) processes. To achieve stable and high-quality annular laser DED (AL-DED) of aluminum alloy, an in situ thermal field assistance system was designed, wherein a preheating-cooling temperature control thermal balance model was established. The thermal field assistance system effect during the AL-DED process of AlSi10Mg has been evaluated, and the control ability of the thermal balance model on absorptivity and temperature field has been analyzed. A continuous 500-layer AL-DED forming of the aluminum alloy was conducted. The results indicate that the in situ thermal field assistance control system can achieve thermal balance during the aluminum alloy component AL-DED process, causing stable laser absorption rate and uniform temperature fields, while reducing surface roughness of components to 2.3 μm. The microstructure and elemental distribution were uniform, transforming the Al–Si eutectic structure from a mesh-like to a dispersed distribution and, consequently, achieving the deposition of a 500-layer, 2.0 mm-thick Al thin-walled component with high dimensional accuracy and stability. This thermal field assistance system effectively improves the stability of absorptivity and the thermal field, providing novel ideas for high-quality AL-DED additive manufacturing of materials sensitive to thermal fields and large absorptivity fluctuations, such as aluminum and copper.
Anaesthetic Management of Cardiac Myxoma Patient with Systemic Involvement: A Case Report
Authors: M Sharma , R Chauhan , V Kumar , R Jain
Published: January 2025

Although the metastatic involvement of heart is more common, the incidence of Primary Cardiac Tumour is very less (0.001-
0.03 percent of the population). Myxomas, the commonest Primary Cardiac Tumours, are usually benign. However, they can
manifest symptoms of systemic involvement, depending upon their location. 75% of the myxomas are located in the left atria of
the heart, although no chamber of the heart is immune. Commonly they have pedunculated morphology, with peduncle usually
attached to the atrial inter-atrial septum. The symptoms of systemic involvement are common when the myxomas are located
in left atria. Diagnosing these Cardiac myxomas can be challenging, especially when the presentation is diverse due to systemic
involvement. Echocardiography is helpful in the diagnosis of these cases, although there are reports of various blood markers to
be helpful. Once the diagnosis is made, tumour excision is to be undertaken in a timely manner. We present a case of patient left
atrial myxoma that had signs of involvement of multiple organs- lungs, abdomen and nervous system. We will be discussing the
manner in which we proceeded with the case, taking care of involved organs and optimization of their functions along with the
literature review of such cases in this article.
Orden espontáneo: Un punto de unión entre la Teoría de los sentimientos morales y La riqueza de las naciones de Adam Smith
Authors: Ribeiro Mathias Nicolas
Published: January 2025

El objetivo de este trabajo será comprender el alcance que el concepto de “orden espontáneo” tiene como fundamento del origen de la moralidad y del mercado en el pensamiento de Adam Smith. Nuestra tesis se resume en afirmar que la idea del “orden espontáneo” parece establecer una posible unión entre las dos obras, ofreciéndose como fundamentación del origen de la moral y del mercado. Dividiremos este trabajo en cuatro partes: las primeras dos se enfocan en realizar un bosquejo de los dos perfiles que Smith logró definir en sus obras, el hombre económico y el hombre moral. En la tercera, argumentamos que en el autor escocés tanto la actividad moral como la económica logran comprenderse en cuanto a su origen y a su desarrollo por medio de la idea del “orden espontáneo”, aunque él no haya utilizado precisamente ese vocablo para referirse a ella. Finalizaremos en la cuarta parte con breves conclusiones.
Presencia telemática y presencia personal humana. Una aproximación desde Tomás de Aquino y Merleau-Ponty
Authors: Moya Patricia , Carreño Juan Eduardo
Published: January 2025

Los avances tecnológicos informáticos, catalizados por la reciente pandemia, han promovido las interacciones humanas telemáticas. En el lenguaje corriente, este tipo de intercambio suele contrastarse con una presencia que se describe como “física” o “corporal”. Cabe preguntarse, no obstante, qué es lo propio y distintivo de esta presencia cuando ella está referida a entidades personales, es decir, a cuerpos personales o, si se prefiere, a personas corporalizadas. En este artículo examinamos esta cuestión desde una perspectiva ontológica de inspiración tomista, pero en diálogo con las ricas especulaciones que nos ha dejado Maurice Merleau-Ponty sobre la presencia y percepción humana.
GÜZEL SANATLAR LİSESİ MÜZİK BÖLÜMÜ ÖĞRENCİLERİNİN SEÇMEYİ DÜŞÜNDÜKLERİ MESLEKLER ve SEÇME NEDENLERİ
Authors: Parpucu Hüseyin
Published: January 2025

Bu araştırma ile güzel sanatlar lisesi müzik bölümündeki öğrencilerin müzik alanındaki seçmeyi düşündükleri meslekler ve bu seçimlerinin ardında yatan nedenlerin çeşitli değişkenlere göre incelenmesi amaçlanmaktadır. Araştırma, nicel desenli tarama araştırması ile şekillenmiş ve Türkiye’nin 7 bölgesinde yer alan güzel sanatlar lisesi müzik bölümü 11. ve 12. sınıf düzeyindeki toplam 292 öğrenci ile yürütülmüştür. Araştırmada veri toplama aracı olarak araştırmacı tarafından geliştirilmiş olan bir “Anket” kullanılmıştır. Veri toplama aracından elde edilen verilerin analizine yönelik olarak SPSS 25 programı aracılığıyla “Ki Kare”, “Mann-Whitney U testi” ve “Kruskal-Wallis H testi” kullanılmış; hangi gruplar arasında fark olduğuna (Post Hoc) yönelik olarak ise “Ki Kare” testi için “Z testi”; “Kruskal Wallis H testi” için “Mann-Whitney U testi” kullanılmıştır. Elde edilen genel sonuçlara göre, öğrencilerin yaklaşık %10’luk bir kısmının mezun olduktan sonra müzik alanına yönelik bir meslek seçmeyi planlamadığı; müzik alanındaki herhangi bir meslek seçmeyi planlayan öğrencilerin ise çoğunlukla öğretmen olmak istediği ile ilgili sonuçlara ulaşılmıştır. Meslek seçme nedenleri incelendiğinde ise, öğrencilerin çoğunlukla ilgi alanlarını veya yeteneklerini göz önünde bulundurarak seçim yaptıkları da elde edilen genel sonuçlardan biridir.
ERKEN ÇOCUKLUKTA ESNEK DÜŞÜNME ÖLÇEĞİNİN GEÇERLİK GÜVENİRLİK ÇALIŞMASI*
Authors: Çağlak Elif , Kandır Adalet
Published: January 2025

Araştırmanın amacı Erken Çocukluk Döneminde Esnek Düşünme Ölçeği'nin güvenirlik ve geçerliliğinin incelenmesidir. Araştırmada genel tarama modeli kullanılmıştır. Araştırmanın evrenini 2020-2021 eğitim öğretim yılında Milli Eğitim Bakanlığına bağlı okullara devam eden 60-96 aylık çocukların ebeveynleri oluşturmuştur. Araştırmanın çalışma grubu uygun örnekleme yöntemiyle seçilen 573 çocuğun ebeveynlerinden oluşmaktadır. Araştırma kapsamında veriler iki aşamada (deneme ve esas uygulama) toplanmıştır. Veri toplama aracı olarak araştırmacılar tarafından geliştirilen 'Erken Çocuklukta Esnek Düşünme Ölçeği' ve 'Kişisel Bilgi Formu' kullanılmıştır. Araştırma sonucunda üç alt boyuttan (bilişsel esneklik, duygusal esneklik, sosyal esneklik) ve 99 maddeden oluşan 'Erken Çocuklukta Esnek Düşünme Ölçeği'nin geçerli, güvenilir ve cinsiyete dayalı ölçme değişmezliğine sahip bir ölçüm aracı olduğu sonucuna varılmıştır.
ADİL MATEMATİK EĞİTİMİ ODAKLI FARK ETME BECERİLERİ
Authors: Çelebi Emine Gül
Published: January 2025

Matematik toplumlar ve bireyler için, gelecekteki fırsatlara erişimde önemli bir eşik görevini üstlenmektedir. Toplumun tüm bireylerinin nitelikli bir matematik eğitimi ve öğrenme imkânlarına erişimi sağlanarak düşünme, algılama ve problem çözme yetenekleri gelişmiş, nitelikli iş gücüne katılabilecek, üretken ve mutlu bireyler olarak yetişme hakları bulunmaktadır. Ancak, özellikle savaşlar, salgın hastalıklar, doğal afetler ve ekonomik sarsıntılar; gelir eşitsizliklerinin belirginleşmesine neden olmaktadır. Öğrenciler arasında mevcut olan ve kendilerinin dışındaki koşullardan kaynaklanan fırsat uçurumlarının ortadan kaldırılmasına duyulan ihtiyaç ülkemizde de yine benzer nedenlerle daha da acil bir hal almıştır. Öğretmenlerde fark etme ise; sınıfta karşılaştıkları önemli durumları anlamlandırma, yorumlama ve etkili bir şekilde analiz edebilmeleri; öğretimlerini buna göre uyarlamalarını sağlayan becerileri içermektedir. Bu çalışmada adil matematik eğitimi ve matematik öğretmeni fark etme becerisi çerçeveleri birlikte ele alınarak tartışılmıştır. Öğretmen fark etme becerisinin matematik eğitiminde süreğenleşmiş eşitsizlikleri irdelemek için önemli bir yapı olduğu görülmektedir. Öğretmen fark etme becerisi öğrencinin ve matematiğin tarihi ve kültürünü; bunların var oldukları sosyal, tarihsel ve politik bağlamlar içinde ele almasının gerekliliğini ortaya koymaktadır. Bu sebeple titizlikle matematik öğretmen adaylarının eğitimine odaklanılması temel hedefi adil ve nitelikli matematik eğitimini hayata geçirmek olan ve buna yönelik fark etme becerilerinin gelişiminin izlenebileceği ve analiz edilebileceği kapsamlı çalışmalar yapılması gerekmektedir.
Three new species of flat mites (Acari: Tetranychoidea: Tenuipalpidae) from alpine New Zealand
Authors: Khaustov Alexander A. , Minor Maria A.
Published: January 2025

Female, male and deutonymph of Acaricis brevicaudus sp. nov., female and deutonymph of Dolichotetranychus tuberculatus sp. nov., and female of Pentamerismus corniger sp. nov. are described and illustrated from alpine cushion fields in New Zealand. Both A. brevicaudus sp. nov. and D. tuberculatus sp. nov. are associated with the cushion-forming ultra-dwarf shrub Dracophyllum muscoides Hook. f. (Ericaceae). The host plant for P. corniger sp. nov. is currently unknown. The diagnosis of Acaricis Beard and Gerson is modified. Additionally, Pentamerismus is recorded from New Zealand for the first time.
Enhanced breathing effort in pulmonary function tests by CO2/O2 gas mixture and barometric whole-body plethysmography in healthy and feline lower airway disease cats
Authors: Chang Wei-Tao , Lo Pei-Ying , Wu Huey-Dong , Chen Hui-Wen , Lin Chung-Hui
Published: January 2025

Objective

Enhancing ventilatory effort during pulmonary function testing can help reveal flow limitations not evident in normal tidal breathing. This study aimed to assess the efficacy and tolerability of using a CO2/O2 gas mixture to enhance tidal breathing with a barometric whole-body plethysmography system in both healthy cats and those with feline lower airway disease (FLAD).

Methods

This prospective study included healthy cats and those with FLAD, which underwent pulmonary function testing and were exposed to a 10% CO2/90% O2 gas mixture in a barometric whole-body plethysmography chamber, with CO2 concentrations maintained within the target range of 5% to 10%.

Results

A total of 10 healthy cats and 15 FLAD cats were included. In healthy cats, tidal volume, minute volume, peak inspiratory flow, and peak expiratory flow per kilogram body weight increased significantly by medians of 4.3-, 3.5-, 3.1-, and 4.0-fold, respectively (P = .005). Cats with FLAD showed similar results, with 4.1-, 3.2-, 2.8-, and 3.7-fold increases (P < .001). Respiratory rate decreased in both healthy (52 to 40 breaths/min; P = .005) and FLAD cats (57 to 45 breaths/min; P = .04) after CO2 enhancement. All cats tolerated the CO2/O2 gas mixture well, with recovery within 60 to 120 seconds after returning to room air.

Conclusions

A CO2/O2 gas mixture successfully enhanced ventilatory variables in tidal breathing analysis and showed good tolerability in both healthy and FLAD cats.

Clinical Relevance

This approach provides a practical option for short-term breathing effort enhancement in cats for clinical settings.
Green Technology Innovation, Green Financing, and Economic Growth in G7 Countries: Implications for Environmental Sustainability
Authors: Elhassan Tomader
Published: January 2025

This study examines the relationships among green technology innovation, green financing, economic growth, and environmental sustainability in G7 countries using annual data from 1990 to 2022. It uses the cross-sectionally augmented autoregressive distributed lag model to estimate environmental sustainability through two indicators: ecological footprint and carbon dioxide (CO2) emissions. The CO2 emissions model indicates that green financing negatively affects emissions, highlighting the need to reduce them and promote sustainable practices. Conversely, energy consumption and real GDP per capita (RGDP) positively impact CO2 emissions. Green technology innovation also reduces CO2 emissions, but its short-term effects may be limited owing to initial energy consumption and regulatory challenges. The ecological footprint model demonstrates that, in the long term, green technology innovation helps lower the ecological footprints of G7 countries by promoting infrastructure development and reducing resource consumption. However, short-term constraints and high initial costs hinder this progress. Green financing is essential for achieving long-term sustainability. Energy consumption positively influences the ecological footprint, while short-term RGDP growth increases it. However, long-term RGDP may decline owing to sustainability policies, technological advancements, and effective environmental legislation. These findings underscore the importance of balanced policies that prioritise green finance in the short-term to mitigate environmental impacts while fostering long-term investments in green technology innovation. Additionally, enhancing international cooperation and aligning investments with green objectives are crucial for achieving sustainable prosperity and minimising environmental harm.
Fixed Points in Multiplicative Metric Spaces
Authors: Bouhadjera Hakima , Messadek Rayane , Biaci Rania
Published: January 2025

In this article, using only our recent concept of occasionally weakly biased mappings of type (A), in multiplicative metric spaces, we could find unique common fixed points.
New properties of the Intermediate Point from Bonnet Theorem
Authors: Pop Emilia-Loredana , Duca Dorel I. , Raţiu Augusta
Published: January 2025

In this paper, the following result is presented: if f, g : [a, b] → ℝ are two continuous functions and f is monotone, then there exists a function ̄c : [a, b] → [a, b] continuous in a with the property:

∫
a
x

f

(
t
)

g

(
t
)

d
t
=
f

(
a
)

∫
a

c
¯

(
x
)

g

(
t
)

d
t
+
f

(
x
)

∫

c
¯

(
x
)

x

g

(
t
)

d
t
,

\int_a^x {f\left( t \right)g\left( t \right){\rm{d}}t = f\left( a \right)\int_a^{\bar c\left( x \right)} {g\left( t \right){\rm{d}}t + f\left( x \right)\int_{\bar c\left( x \right)}^x {g\left( t \right){\rm{d}}t,} } }

for all x ∈ [a, b]. Then, under specified conditions, the function ̄c that is differentiable at point a is presented, and

c
¯

′

(
a
)

\bar c'\left( a \right)

is also calculated.
Ozone decomposition – state of the art and new approaches
Authors: Batakliev Todor , Georgiev Vladimir , Rakovsky Slavcho , Zaikov Gennadi E.
Published: January 2025

The effective ozone decomposition is still a scientific challenge because of its rising industrial use in global scale. Wide application of high ozone concentrations forces researchers to work on new catalytic systems for ozone removal concerning mostly the surrounding human environment (airplane cabins, copiers, laser printers, sterilizers, etc.). It is not an easy task considering the fact that above concentration of 0.1 mg/m3 the ozone could seriously harm human health. Current studies estimate a huge number of untimely deceased people per year on a global scale as a direct consequence of air pollution. It is imposing to reinforce the efforts in workable ozone decomposition on ground atmospheric layer as an important part of air purification process. This review comprises general look on basic physico-chemical properties of ozone completed by recently reported literature about catalytic ozone destruction. Discussion over kinetics and mechanisms of ozone decomposition reaction will be represented in order to do an attempt to clarify these most outstanding parts of the topic.
Health risks associated with benzene formation in health supplements – An appraisal
Authors: Sharma Priyanka , Maithani Mukesh , Gupta Vikas , Yadav Mayank , Bansal Parveen
Published: January 2025

Benzene, classified as class-1 human carcinogen by International Agency for Research on Cancer (IARC), is a well-studied chemical over the century and is directly associated with acute and chronic health effects. Evidences reflect that benzene exposure leads to Acute Myeloid Leukemia and Acute Non-Lymphocytic Leukemia. Benzene may enter food and formulations through various environmental factors and due to inferior manufacturing techniques. Moreover, the formulations containing sodium benzoate and ascorbic acid/citric acid as preservative/constituent of herbal ingredient are at greater risks of benzene contamination by oxidative decarboxylation reaction. Although FDA has set a limit for benzene content in products yet cases with high level have been reported. At the same time the long-term use of formulations, even with permissible limits of benzene, may increase risk of carcinogenicity. Harmful health effects due to environmental and occupational exposures to benzene have been sufficiently reported, however, no such reports for generation of benzene in food and pharmaceutical products exist. There is a need to make the scientific fraternity involved in food products, formulations, and food supplements and to be aware of the undesirable effects of multiple and indiscriminate use of preservatives leading to benzene generation. So, the present manuscript highlights the mechanism of benzene formation in food products/formulations, factors affecting benzene formation, metabolism, toxicity and other health effects.
Hepatoprotective effects of quercetin against natural and chemical toxicities: A review
Authors: Bagheri Sara , Tabeshpour Jamshid , Hosseinzadeh Hossein , Hashemzaei Mahmoud , Karimi Gholamreza
Published: January 2025

Liver metabolizes and detoxifies xenobiotics and toxicity in this organ can lead to dysfunctionality. Flavonoids such as quercetin (QRC) have been shown to possess protective effects against different liver disorders. This flavonol exerts its hepatoprotective effects via different mechanisms including increase of nuclear factor (erythroid-derived 2)-like 2 protein expression, sirtuin 1, thioredoxin and thioredoxin reductase and decrease in nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and myeloid differentiation primary response gene 88 (MYD88). The aim of the current review was to examine the possible protective effects of QRC against different natural and chemical toxic agents-induced hepatotoxicity, so that it could be considered as a hepatoprotective agent in clinical trials. Based on a variety of keywords, Medline, Scopus, Web of Science and Google scholar were searched for all related published literature. Because of insufficient clinical trials on this topic, this review contains only in vivo and in vitro investigations. In this regard, more clinical trials are required to be performed to confirm QRC beneficial properties in human hepatotoxicity. Collectively, QRC could be a promising natural compound in reversing the toxic effects of different toxic agents in the liver.
Cytotoxic profile of different extracts of M. calabura fruits and antiadipogenic activity of ethanol extract in 3T3-L1 cells
Authors: Renjith Mahasenan , Nevin Kottayath Govindan
Published: January 2025

Lipid accumulation is the root cause of obesity, which is a global epidemic metabolic syndrome affecting all populations worldwide. Due to the deleterious hepatotoxic and cardiotoxic effects of various antiobesity drugs, the attention now turns on to various natural products for low toxic therapeutic molecules against lipid accumulation. Muntingia calabura is a shrub or tree, whose fruits are edible. This study evaluated the possibility of the ethanol extract from fruits of M. calabura as functional food towards reduction of obesity. Anti obesity and cytotoxic activity of this extract was tested in 3T3-L1 preadipocytes. The in vitro antioxidant activity was also tested colorimetrically. Results showed that the ethanol extract of M. calabura fruits has significant oxygen, hydrogen and DPPH radical scavenging activity in vitro. The extract dose-dependently suppressed adipocyte differentiation and lipid accumulation in 3T3-L1 cell line as indicated by changes in cellular lipid levels evaluated by Oil red O staining. Taken together, these results suggest that the ethanol extract of M. calabura fruits may have antiobesity and antioxidant effects with the potential for use in obesity management in humans.
Toxicity and mutagenic activity of benzophenone isolated from Garcinia brasiliensis fruit in healthy and Schistosoma mansoni infected mice
Authors: Castro Aline Pereira , Giannini Laila Santos Vieira , De Paula Maia Tatieska , Costa Lellis Henrique , Viana André Luiz Machado , Dos Santos Marcelo Henrique , Rodrigues Maria Rita , Couto Flávia Fernanda Bubula , De Oliveira Carine Ervolino , Souza Raquel Lopes Martins , Azevedo Luciana , Marques Marcos José
Published: January 2025

7-epiclusianone (7-epi), a benzophenone isolated from fruits of Garcinia brasiliensis, presents remarkable biological activities as the schistosomicidal. However, there is a need to evaluate the toxic effects of 7-epi by analyzing liver function markers (aspartate-aminotransferase, alanine-aminotransferase, albumin, total proteins, and glucose) and a renal marker (creatinine), and beside that also comet (COM), micronucleus (MN), apoptosis (APOP), and histopathological in vivo analyzes. Although 7-epi at doses of 100.0 and 300.0 mg/kg (for five consecutive days) did not cause biochemical alterations to the male swiss mice (8 weeks old), it was not able to mitigate the damage caused by S. mansoni eggs. In the COM, MN, and APOP assays with marrow and the colon, 7-epi at doses of 10.0, 50.0, and 100.0 mg/kg (for fourteen consecutive days) caused no damage to the DNA and was able to protect the cell from damage caused by doxorubicin (16.0 mg/kg) and N, N’-dimethylhydrazine (30.0 mg/kg) both by peritoneal route for fourteen days. In the histopathological exams, the liver showed no changes in the dose of 100.0 mg/kg of 7-epi, however, some changes were observed in the 300.0 mg/kg dose. The results obtained in these experiments reveal that 7-epi can be used safely for the treatment of murine experimental schistosomiasis.