bluuebunny/crossref_metadata_2025 huggingface dataset:
Gelişim Çağındaki Çocukların Fiziksel, Sosyal ve Duygusal İhtiyaçları: Nörobilimsel Bulgular ve Bertrand Russell’ın Fikirlerinin Karşılaştırılması
Authors: YÜCE Alp Eren
Published: July 2023

Bu çalışmanın amacı Bertrand Russell’ın eğitim felsefesi görüşleri ile son dönemde giderek önem kazanan nörobilim araştırmalarında ve eğitsel nörobilim alanında ortaya çıkan bulgu ve felsefi görüşleri karşılaştırmaktır. Nörobilim çalışmalarının bulguları ve eğitsel nörobilim tartışmalarına göre öğrenme ve öğrenmenin davranışa dönüşmesini sağlayan en önemli unsurlar biyolojik (fiziksel ve kimyasal), ve sosyal unsurlardır. Bertrand Russell da eğitim hakkındaki görüşlerini bu unsurlara dayandırarak bir eğitim felsefesi geliştirmiştir. Nörobilimsel bulgular öğrenme ve diğer bilişsel faaliyetleri çoklu parametreler üzerinden detaylı şekilde açıklamaktadır. Russell’da özellikle modern toplumların sahip olduğu problemleri bu ayrıntılar ve gündelik dinamikler ile felsefi bir üslüpta tartışmıştır. Yapılan bu karşılaştırmada ortaya çıkan sonuçlara göre; öğrenme ve eylem ilişkisinde, insanın fizyolojik ve duygusal ihtiyaçlarının beraber değerlendirilmesinin önemi, eğitimde özerklik ve serbestinin rolü, cinsel eğitimi, sosyal güç dengeleri ve oyun temaları ön plana çıkan konu başlıkları olmuştur. Ortaya çıkan bu bulgulara göre biyolojik, duygusal ve sosyal unsurların iç içe geçmesi öğrenme ve bilişsel faaliyetler için temel oluşturmaktadır. Bu biyolojik, duygusal ve sosyal unsurların ortaya çıkardığı sosyal ve bireysel ihtiyaçlar da tartışma kapsamında değerlendirilmiştir.
Pedagojik Sanat Eleştirisinin Öğrencilerin Görsel Okuryazarlık Becerilerine Etkisi
Authors: ERASLAN Sevgül , ERASLAN TAŞPINAR Şeyda
Published: July 2023

Bilginin yayılımı, teknolojinin gelişmesi ve görsellerin daha çok kullanılması ile görsel okuryazarlık her insanın aktif bir şekilde her alanda kullandığı bir beceri olmuştur. Sanat eleştirisi yöntemi ise sanat eserlerine görsel ve düşünsel analiz yaparak incelemeyi sağladığından görsel okuryazarlık becerilerinin gelişimine katkı sağlayacak içeriğe sahiptir. Araştırmada “Pedagojik Sanat Eleştirisi yönteminin öğrencilerin görsel okuryazarlık becerilerine olan etkisinin belirlenmesi” amaçlanmıştır. Çalışma grubu ortaokul 8’inci sınıfta öğrenimini sürdüren 90 (60 kız ve 30 erkek) öğrenci ile oluşturulmuştur. Rastgele seçilen deney ve kontrol gruplarının mevcutları 45’er öğrencidir. Araştırma modeli olarak “ön test-son test kontrol odaklı yarı deneysel model” kullanılmıştır. Ön test ve son test olarak “Görsel Okuryazarlık Yeterlilik Ölçeği” kullanılmıştır. Deney grubunun dersleri “pedagojik sanat eleştirisi yöntemi” ile işlenirken kontrol grubunun dersleri “görsel sanatlar öğretim programı” doğrultusunda işlenmiştir. Elde edilen bulgular doğrultusunda görsel okuryazarlık son test puan düzeyleri arasında ölçeğin gerek alt boyutları gerekse de toplam puanında deney grubu lehine farkın anlamlı olduğu görülmüştür. Gruplar kendi içinde ön test ve son test puanlarının karşılaştırılmasında farkın yine deney gurubu lehine anlamlı olduğu görülmüştür. Araştırma sonucunda, katılımcıların görsel okuryazarlık becerilerinin pedagojik sanat eleştirisi yöntemi ile yükseldiği görülmüş ve önerilere yer verilmiştir.
Diyalojik Benlik Teorisi ve Öğretmen Kimliği: Sistematik Derleme Çalışması
Authors: BEYAZBAL Selen , ŞAHİN Çavuş
Published: July 2023

Öğretmen eğitiminden başlayarak, öğretmen kimliğinin mesleki gelişimde önemli bir yeri bulunmaktadır. Çalışmalarda, sıklıkla öğretmen kimliği gelişimi ve öğretmen benlik algısı üzerine çalışılmış olsa da öğretmen kimliğinde benlik gelişimine ve Diyalojik Benlik Teorisi konusunda çalışmalar sınırlıdır. Öğretmen benlik gelişimi için fırsatlar sunan Diyalojik Benlik Teorisi, öğretmenin benliğindeki değişiminden başlayarak, kimlik gelişimi için önemli katkılar sunmaktadır. Alanyazında Diyalojik Benlik Teorisi ve öğretmen kimliğine ait az çalışma bulunmasından dolayı, yürütülen amprik çalışmalarının yönelimlerin bilinmesinin hem Diyalojik Benlik hem de öğretmen kimliği çalışmaları için katkı sağlayacağı düşünülmektedir. Bu araştırmada, Diyalojik Benlik Teorisi ve öğretmen kimliği üzerine yapılan çalışmaların araştırma yönelimleri, sonuç ve önerilerinin sistematik derleme yapılması amaçlanmıştır. Bu çalışma doğrultusunda belirlenen dahil etme ve dışlama ölçütlerine göre 19 makale ve 1 tez belirlenmiştir. Çalışmaların yönelimleri için “Araştırma Yönelim Formu” ve sonuçlar-öneriler için “Sonuç ve Öneri inceleme Formu” kullanılarak tarama yapılmıştır. Verilerin analizinde betimsel içerik analizi kullanılarak araştırmanın yönelimleri ve 8 tema altında toplanan sonuç ve önerileri raporlaştırılmıştır. Araştırmaların yönelimlerinde, yayımlanan çalışmaların ağırlıklı olarak 2021 yılına ait olduğu görülmüştür. Yayımlanan çalışmaların yöntemsel eğilimi olarak ise nitel araştırma yöntemlerinin tercih edildiği görülmüştür. Çalışmaların sonuçlarının ve önerilerinin Diyalojik Benlik Teorisi, kimlik, iç benlik, dış benlik, pozisyonların çoğaltılması, öğretmen eğitimi ve stratejiler temalarına odaklandığı görülmüştür.
FLUOKSETİN VE DÜŞÜK DOZ TRAZODONUN BİRLİKTE KULLANIMIYLA OLASI SEROTONİN SENDROMU DÜŞÜNDÜREN VE NARANJO İLAÇ YAN ETKİSİ OLASILIĞI ÖLÇEĞİ İLE DEĞERLENDİRİLEN BİR OLGU
Authors: AYDIN Sare , BATMAZ Sedat , SÜMBÜL Orhan , AKPINAR ASLAN Esma
Published: July 2023

Serotonin sendromu serotonerjik ajan kullanımı sonrasında

oluşan serotonin reseptörlerinin aşırı uyarılması

sonucu gelişen nadir görülen fakat mortal seyredebilen

sendromdur. Klinik belirti ve bulgular kognitif,

nöromüsküler ve otonomik alanda görülmektedir. Serotonerjik

etkili bir veya daha fazla ajanın birlikte kullanılması

bu sendroma neden olur. Klinik görünümü hafif

şiddette olup gözden kaçabilen olgular olduğu gibi

hayatı tehdit eden, yoğun bakım ve mekanik ventilasyon

gerektiren şiddette de olabilmektedir. Bu yazıda

fluoksetin tedavisine trazodon eklenmesi ve doz artırılması

sonrasında 24 saat içerisinde gelişen serotonin

sendromu düşündüren bir vaka sunulmuştur.
Tandem architectures for artificial thylakoid membranes
Authors: Engelbert Redel
Published: July 2023

In this concept paper, new layered materials, such as multilayer hybrid systems, are described. These materials can be implemented into novel biomimetic devices, which can act as artificial photosystems or as “artificial thylakoid membranes” e.g. for the splitting of water. The architecture can be based on active nanoparticles or small catalytic clusters which can be synthesized from robust, inexpensive, and abundant material precursors. These multi-layered architectures can act as “artificial thylakoid membranes”, which can mimic the photosynthetic apparatus on the nanoscale. The development of “artificial thylakoid membranes” and tandem devices promises a strong impact and benefits for the field of artificial photosynthesis and the development of artificial leaves.
The complex sexuality of “Italian” Hikikomori and the need for better nosographic framing of psychopathological evidence
Authors: Giulio Perrotta , Domenico Piccininno
Published: July 2023

Objective: The definition of “hikikomori” evokes dysfunctional personality pictures already known in the literature and medical practice. The aim is to refute the hypothesis of the need to identify this clinical condition in a new descriptive framework. Materials and methods: Pubmed checklist, clinical interview, and psychometric tests. Results: In the entirety of the selected population, it emerges that the primary disorder is schizoid personality disorder; this is followed by depressive disorder, narcissistic covert disorder, bipolar disorder with depressive prevalence, obsessive disorder, avoidant disorder, and somatic disorder as secondary dysfunctional personality traits. Childhood and/or family trauma, capable of impacting the sexual and affective sphere, is present in almost the entire population. Conclusion: The syndrome should be framed as a specific phenomenon and not as a new psychopathological disorder, as the symptomatological descriptions are similar to the already known schizoid personality disorder; the symptomatological differences among patients should be framed according to a logic of correctives determined by the presence of one or more secondary psychopathological traits that draw a more complex personality picture than the simple nosographic diagnosis of the DSM-V.
A comparable-corpus-based study of informal features in academic writing by English and Chinese scholars across disciplines
Authors: Xia Gao
Published: July 2023

This paper aims at quantitatively and qualitatively analyzing the use and distribution of informality features in a comparable corpus of research articles (rAs) written by L1 Chinese scholars (Css) and L1 English scholars (Ess) across four disciplines. The normalized frequencies of eleven informal features were calculated and compared first between Ess’ and Css’ rAs in the same discipline and then across the four disciplines. Four features, namely first person pronouns, pronominal anaphoric reference, sentence-initial conjunctions/conjunctive adverbs, and imperatives, were identified to be the contributing factors and analyzed qualitatively. The results demonstrate that: (i) there is significant difference in the use of informality features between Ess and Css with Css employing informality features less frequently than Ess; (ii) disciplinary variations are present with Physics rAs sounding more informal and Linguistics rAs more formal; (iii) the distribution of specific informality features presents a diversified picture: Css’ use of first person pronouns and pronominal anaphoric references is less frequent, and their use of imperatives and sentence-initial conjunctions/conjunctive adverbs is more frequent than Ess’. These findings shed light on teaching academic writing and provide writers with some guidance about stylistic choice
Authorial voice in academic writing
Authors: Cheung Yin Ling , Lau Louwena
Published: July 2023

Academic writers represent themselves in their texts in different ways, notably through use of first person pronouns to construct an authorial voice and enhance arguments. This study examines how expert writers in the disciplines of Literature and Computer Science use first person pronouns. The hypothesis is that in the absence of objective fact, Literature writers resort to frequent use of first person pronouns backed by stronger authorial roles to build credibility and convince readers, while Computer Science writers avoid first person pronouns in line with conventional wisdom in the hard sciences. The findings suggest that the general dichotomy between hard and soft sciences regarding first person pronouns usage may not apply in all cases. Our study discusses the similarities and differences in the disciplinary conventions in Literature and Computer Science, thus making contributions towards pedagogy and scholarship of the role of first person pronouns in voice construction in academic texts
Genre practices in mechanical engineering academic articles
Authors: Ngoc Phuong Le Thi , Man PhaM Minh
Published: July 2023

Since move analysis was proposed by Swales (1990), numerous studies have adopted this method to explore organisational patterns in different sections of research articles in a range of disciplines. However, research articles in mechanical engineering have attracted scant attention in genre analysis research. This paper will be among the first to identify move structures of the Results Discussion section of research articles in this under-explored discipline. To this end, it draws on a corpus of 18 original research articles that employ different research types (experimental, theoretical and mixed). The findings show the prototypicality as well as variability in genre practices associated with different disciplinary contexts. The findings have important implications for the design of corpora used in genre analysis
New Trends of Sugarcane Cultivation Systems Toward Sugar Production on the Free Market: A Review
Authors: Sulaiman Andi Amran , Arsyad Muhammad , Amiruddin Achmad , Teshome Temesgen Tilahun , Nishanta B.
Published: July 2023

Sugar is one of the staple food commodities that has an important role in the Indonesian economy. The high demand for domestic sugar has resulted in the inability of sugar factories to meet the demand for sugar consumption because domestic sugar production is still low. This is due to decreased land area and productivity, low sugar yield rates, and low factory efficiency. This paper describes the improvement of sugarcane cultivation to the process of making sugar to support national consumption. The article uses a systematic review method on the latest sugarcane research and reports the conditions directly on the plantation. The results show that the existing sugarcane supply is still less than the factory's demand, so the factory worked inefficiently. Even though the factory has new machines and technology to produce good quality sugar with a capacity of 4,600 TCD, companies can take a coaching approach to the surrounding community to carry out sugarcane cultivation and provide financial support to the surrounding community. Based on the reality of low production and factory efficiency, the government needs to support the sugarcane cultivation system through farming production systems, improving factory machine capacity and labor for sugarcane estate in the global market era.
Sex Ratio, Age Structure and Parasitism in Unaspis mabilis (Hemiptera: Diaspididae) in the Philippines
Authors: Medina Celia dR. , Velasco Luis Rey I. , Quisado Joeseph S. , Limson Joel P. , Posas Darlyn B. , Novio Bryan V.
Published: July 2023

Lanzones scale insect (LSI) has been an important insect pest of lanzones since its first record in 2004. It causes massive defoliation on trees which eventually results to underdeveloped and sour fruits. Different lanzones-growing areas in the Philippines were surveyed for LSI along with its associated parasitoids in commercial lanzones farms located in Laguna (Los Baños,Nagcarlan and Sta. Maria), Oriental Mindoro (Villa Cerveza, Villa Cerveza, San Gabriel-Alcate), Negros (Abante-Pamplona, Poblacion - Pamplona, Lunga, Valencia, Talisay - Negros Occidental, Jawa-Valencia, Lunga-Valencia, Bongbong), Misamis Occidental (Aloran - Misamis Occidental, Calamba, Oroquieta, Sapang Dalaga, Plaridel), Camiguin (Catarman, Poblacion, Sagay, Tagdo, Mahinog), North Cotabato (Makilala, Kidapawan, and Kabacan) and Sulu (Maimbung, Patikol,Talipao). From each collection site, a total of 10 infested trees were sampled at random with leaflets (N=10) collected in four cardinal directions around canopy. Leaflets were scanned, photographed, and transported to the laboratory. Population estimates of each local population was obtained along with demographic structure viz. age structure and male-female sex ratio. The sample per tree were kept individually in customized cages for parasitoid emergence and determination of parasitization rate. Parasitoids were identified as Aphytis sp., Encarsia sp. and 2 other unidentified species. LSI population and percent parasitism in Laguna were quite high compared to North Cotabato. Results of this study will contribute to the basic knowledge needed to improve control strategy on LSI.
Preparation of Artificial Urine v1
Authors: not provided alow
Published: July 2023

A method for producing artificial urine as a media for bacterial experiments
Mapping Visualization of Maritime Technology Study in Indonesia with Blibiometric Analysis Using VoSviewer
Authors: Saputra Rizqiya Windy , Siregar M. Sapril
Published: July 2023

Indonesia is a large country with many spreading archipelagos. The condition makes Indonesia a potential country in maritime sectors. The potential condition establish maritime technology is a topic that has begun to interest many researches. The strong desire of researcher will also get support from the many sources of citations that are now appearing and can be used as references. Even though it has a wide area of expertise, the researches concerning maritime technology is very little at present. This research aims to collect the trends of maritime technology research in Indonesia by performing bibliometric analysis from scientific papers indexed by partly free scholarly database named Dimension. This research analyzes the numbers of document published, the most cited papers, and the productivity of maritime researchers in specific area of maritime technology. Some keywords focused on this researched were minned by clustering using VOSviewer. As the result, this study hopefully provide an overview of current research on maritime technology in Indonesia and provide the right direction for researchers with maritime technology research interest.
Multidimensional Frailty and Traumatic Brain Injury among Older Adults: A Literature Review
Authors: Gerber Kathryn , Iriarte Evelyn , Sierra Carmen Josefa
Published: July 2023

Background. Numerous health conditions in the older adult population can be attributed to falls, including traumatic brain injury (TBI), which can lead to devastating short and long-term sequelae. Older adults are also more likely to experience frailty, which encompasses physical, psychological, and social deficits that may lead to adverse health outcomes. Our literature review synthesizes current evidence for understanding frailty in the context of TBI among older adults using the Integral Model of Frailty as a framework. Content synthesis. A total of 32 articles were identified, and 9 articles were included. The results of this review indicate that outcomes resulting from TBI are closely linked to the physical, psychological, and social domains of frailty. Conclusions. A small amount of literature currently examines frailty in the context of TBI among older adults. Using the Integral Model of Frailty to understand frailty in the context of TBI can help clinicians anticipate patient outcomes and improve care plans. We emphasize the need for a greater understanding of TBI concerning frailty to improve health outcomes among older adult patients.
Stress levels and coping strategy of nursing students in online learning during COVID-19 Pandemic. A mixed- methods study
Authors: Hemme Tambunan Evelyn , Renolita Sinaga Rosnancy
Published: July 2023

Objective. To explain the stress level and coping strategies of nursing students in online learning during Covid-19pandemic.
Methods. Explanatory sequential mixed method QUAN-QUAL study conducted at a private university inBandung, Indonesia. Of the 260 nursing students, 157 consented to participate and answered a Depression Anxiety Scale- 42 (DDAS-42) and The Ways of Coping in the Indonesian version. The participants of the quantitative phase with the indicative of stress were interviewed individually (n=17) to provide an in-depth understanding of the students’ experiences of stress and coping strategy in online learning.
Results. Almost one out of two students (47.1%) had some level of stress (16% between severe and extremely severe). Most nursing students (45.9%) used emotion focused coping strategies. Stress level was significantly higher among female students and internship academic level (%0.05). Nursing students’ sources of stress were new experiences and hindrances to online learning. Coping strategies included seeking support and positive acceptance.
Conclusion. A high proportion of nursing students experienced stress during their education process in COVID-19 times; they used specially emotion-focused coping strategies to reduce barriers to online learning.
Comparación del léxico del mundo vitivinícola del ALEA y del Condado de Huelva en la actualidad
Authors: Galloso Camacho María Victoria , Robles Gómez Margarita
Published: July 2023

En el marco actual de la Cátedra del Vino de la Universidad de Huelva y la investigación que estamos llevando a cabo para recopilar el léxico del mundo vitivinícola de La Palma del Condado, realizamos esta propuesta de cotejar los datos actuales, obtenidos de La cultura de la viña en la región del Condado (Roldán, 2003) y mediante encuestas, con aquellos que recogiera el ALEA en los años cincuenta del siglo pasado en los mapas 187-220. Como ya realiza el grupo VitaLex de la Universidad de Granada, ello nos va a permitir establecer patrones de vitalidad y estudios sobre la pervivencia o no del léxico del vino, así como posibles variaciones léxicas argumentadas desde los cambios sociolingüísticos que definen el mundo comercial actual. El objetivo es seguir investigando y dando a conocer el patrimonio inmaterial onubense, en esta ocasión, desde la presentación del léxico vitivinícola de un área geográfica distinguida por su denominación de origen y cómo este léxico ya había sido recogido en el ALEA describiendo objetivamente la historia y la identidad de esta región.
significado (dimensional) de los adjetivos dimensionales del español
Authors: Ynduráin Pardo de Santayana Carlos
Published: July 2023

El objetivo de este artículo es analizar la relación existente entre los adjetivos dimensionales (aquellos que hacen referencia a las magnitudes de un objeto en el espacio) del español y las distintas partes de los objetos según sea su forma, su orientación y la perspectiva del hablante-observador. Para ello, adaptamos al estudio de las entidades individuales los distintos modelos conceptuales recogidos por Levinson (2003) para las relaciones espaciales entre dos objetos: el modelo absoluto, el modelo relativo y el modelo intrínseco. La nuestra es, por lo tanto, una investigación semántica en la que se aborda la polisemia de los adjetivos dimensionales tratando de vincular dicho fenómeno lingüístico con los mecanismos cognitivos de conceptualización del espacio: a pesar de que nuestra aportación podría servir de base a un futuro desarrollo de carácter lexicográfico, no buscamos llevar a cabo una mera enumeración de los sentidos asociados con cada adjetivo dimensional concreto, sino sacar a la luz los principios que subyacen a dichas conexiones entre forma y significado.
Constitutional Law Responsibility of Candidates for Preliminary Election
Authors: Mazurevsky K. S.
Published: July 2023

The paper is devoted to the study of such a topical issue of modern political life in Russia as the procedure of preliminary election (primaries) by political parties. In particular, the author of the paper, using the example of intraparty regulation of the pre-election procedure by the All-Russian Political Party «Edinaya Rissia,» elucidates the issue of responsibility of the candidates at the primaries under constitutional law. The paper analyzes various grounds of responsibility of the candidates of the preliminary elections under constitutional law. The author proposes the classification of the grounds of liability into the grounds of a legal nature and the grounds of political nature. The paper examines such mechanisms of application of measures of constitutional law responsibility of candidates of preliminary elections as refusal to register candidates and exclusion from the list of candidates of primaries; their comparative legal analysis with similar institutions of electoral legislation is carried out. In addition, the paper explores specific features of the constitutional law responsibility of the candidates of the preliminary election and specifics of its application, including in comparison with the norms of election legislation.
Legal Regulation of Banking in the New Regions of the Russian Federation
Authors: Tarasenko O. A.
Published: July 2023

In October 2022, 4 new constituent entities were admitted to the Russian Federation: the Donetsk People’s Republic, the Luhansk People’s Republic, the Zaporozhye and Kherson regions, which put on the agenda the issue of integrating their banking business into the federal legal field. The study focuses on the following questions: how this process is going and what impact it makes on the national banking system as a whole. According to the results of the study, it is revealed that the legal regulation of the banking system of new constituent entities of the Russian Federation is undergoing a transitional period characterized by the effect of the norms adopted in these regions before they entered into the Russian Federation, as well as acts of emergency legislation. The author determines the factors influencing banking activity in the new constituent entities of the Russian Federation: the need for legal transformation, implementation of the special military operation, unfriendly actions on the part of the United States and foreign states and international organizations that have joined them. Extremely low availability of banking services in these constituent entitties of the Russian Federation makes it necessary to open branches and subsidiaries of Russian banks. To sum up, taking into account conclusions made about the nature of integration, the author proposes measures aimed at supporting the banking system not only in the new regions, but also in the Russian Federation as a whole: increasing limits on cash withdrawals; writing off loans the collateral for which was lost during hostilities for individuals and legal entities located in new regions; resumption of the work of exchange offices; acceleration of the process of introducing a non-bank payment service provider to the banking market; creation of a fund for settlement of losses in the banking sector; development of a mechanism for parliamentary control over acts of emergency regulation adopted by the Bank of Russia, the President of the Russian Federation and the Government of the Russian Federation.
Cryptoassets Seizure in Criminal Procedure in the Russian Federation: Possible Ways of Development
Authors: Ludanina A. V.
Published: July 2023

The paper analyzes the existing practice of seizing cryptocurrencies in the domestic legal order. It is noted that the law enforcer needs that the legislator create criminal procedural novels aimed to seize cryptocurrencies. The paper provides domestic practice cases, recognizing cryptoassets as property in the understanding of civil law. The mechanism of using an investigative experiment to convert cryptoassets into cash is criticized. The author analyzes the possibility of applying the concept of privilege against self-disclosure during an investigative experiment to convert cryptoassets into cash. The paper proposes models that can be chosen by the legislator when implementing the seizure of cryptocurrencies. The types of crypto-carriers are analyzed. The author concludes that due to the wide variety of types of cryptocurrencies a single model will not be enough for law enforcement agencies when seizing such assets. The author suggests the legislator to choose a mixed model of criminal procedure regulation of seizure of cryptoassets as well as to introduce a new coercive measure in the Code of Criminal Procedure of the Russian Federation in the form of converting digital assets into cash.
Confiscation of Property in the Context of Sanctions Policy: Legal Aspects
Authors: Slepak V. Yu.
Published: July 2023

Western sanctions regimes show a high degree of coordination. This applies to almost all aspects of the sanctions policy, including approaches to the possibility of confiscating the property of persons subject to blocking sanctions. However, countries that support autonomous sanctions against Russia follow different paths towards the common goal. The emerging approaches to confiscation make it possible to single out two main areas of legal regulation of this issue. In the legislation of the respective country confiscation can be considered either as an instrument of sanctions legislation, or as a measure of responsibility for violating sanctions legislation. Only two countries have so far chosen to use confiscation as an independent instrument of sanctions policy: Ukraine and Canada. Perhaps the United States will join them, but at present, similar to Switzerland, they use confiscation only as part of countering illegal activities. The draft directives developed by the European Commission demonstrate the EU’s commitment not to jeopardize the obligation to protect private property and provide for the possibility of confiscation in exceptional cases as a measure of influence in the fight against criminal activity. Given the importance of protecting private property for a favorable investment climate, it is most likely that the second path will become dominant: asset confiscation will be seen only as a means of responding to violations of the laws of a country that supports autonomous sanctions.
Long-term results of early orthodontic treatment of children aged 3–5 years
Authors: Shishmareva Anastasia S. , Bimbas Eugenia S.
Published: July 2023

Background. The frequency of dentoalveolar anomalies and the severity of dentoalveolar disorders in children increases with age. Early orthodontic treatment allows to take advantage of the growth and eruption of teeth and stop pathological development before significant compensatory deformities of the dentition occur, which are more difficult to treat.
Aim. To study the long-term results of early orthodontic treatment of children aged 35 years.
Material and methods. A prospective study of the long-term results of orthodontic treatment in 50 children aged 35 years was carried out. The state of the dentoalveolar system of children was analyzed: the magnitude of the disproportion in the sagittal, transversal and vertical directions; direction and magnitude of displacement of the lower jaw; the presence of anomalies in the development of teeth before and 3.5 years after treatment. Statistical analysis was carried out using the program Statistica 13.3. The ShapiroWilk and KolmogorovSmirnov tests, asymmetry and kurtosis indicators, and the Student's test were used.
Results. A high frequency (52%) of cases of severe occlusion disorders was revealed (occlusion disorders in two planes 44%, in three 8%). Often there was a displacement of the lower jaw 72%. These disorders require early orthodontic treatment. When analyzing the results of early orthodontic treatment after 3.5 years, physiological occlusion was established in 86% of cases: a decrease in the size of the direct sagittal fissure (before treatment 3.92.5, after treatment 1.11.5; p=0.000005); elimination of the reverse sagittal fissure (before treatment 0.80.5, after treatment 0.030.1; p=0.000000); decrease in the depth of vertical overlap (before treatment 4.60.6, after treatment 2.21.1; p=0.000043); elimination of the vertical gap (before treatment 3.121.3, after treatment 1.02.0; p=0.05011); elimination of exocclusion (before treatment 4.92.3, after treatment 0.30.9, p=0.000000); elimination of endocclusion (before treatment 5.50.7, after treatment 0.70.3, p=0.033475); elimination of the displacement of the lower jaw. In 14% of cases in children, the occlusion was not ideal, while the physiological development of the dentition was noted.
Conclusion. Early orthodontic treatment of children aged 35 years can eliminate severe disorders and, in most cases, create conditions for the physiological development of the dentoalveolar system.
The role of plant adaptogen in the correction of parameters of the hemostasis system during ­emotional-immobilization stress in the experiment
Authors: Obraztsova Lolita A. , Bondarchuk Yulia A. , Shakhmatov Igor I. , Manaeva Irina N. , Lisina Svetlana V.
Published: July 2023

Background. Maladaptive changes on the part of various organs and systems, in particular on the part of the hemostasis system, are manifested in extreme forms of physical inactivity, one of which is immobilization stress. If the organism is also subjected to psycho-emotional effects at the same time, then the combined effect of stressors is accompanied by an increase in maladaptive disorders.
Aim. To establish the influence of emotional-immobilization stress on the hemostasis system, as well as the possibility of correcting changes by taking a course of eleutherococcus.
Material and methods. The experiment was conducted on male rats, which were divided into four groups: the first group (n=14) control, the second group (n=14) animals treated with eleutherococcus for 30 days, the third group (n=14) rats, subjected to a single 3-hour water-immersion dipping, the fourth group (n=14) animals that took eleutherococcus for 30 days before the water-immersion dipping. The state of the hemostasis system was assessed in all experimental groups. Statistical processing of the results was performed using the Statistica 10.0 package (Statsoft, USA). Significance of differences was assessed using the nonparametric MannWhitney test and Student's t-test.
Results. A single immobilization effect was accompanied by hypercoagulable changes, which characterized by shortening of the silicone (p=0.001) and kaolin (p=0.002) time. Completion of the 30-day adaptogen intake followed by emotional immobilization stress was accompanied by an increase in silicone (p=0.001), kaolin (p=0.021), prothrombin (p=0.021) and thrombin (p=0.006) time, which indicated hypocoagulation changes.
Conclusion. The immobilization effect is characterized by hypercoagulability against the background of a decrease in the anticoagulant and fibrinolytic activity of the blood plasma; the course intake of eleutherococcus prior to immobilization is accompanied by hypocoagulant changes and an increase in the anticoagulant activity of the blood plasma.
The prevalence of mental disorders in patients with posterior segment eye disease
Authors: Jakovlev Denis A. , Shurygina Anna D. , Kuzmina Svetlana V. , Rascheskov Alexandr Yu.
Published: July 2023

The article presents materials from foreign and domestic literature, that indicate the relationship between ophthalmic pathology and mental disorders. The most common mental disorders are depression and anxiety among patients with visual impairment. The prevalence of comorbidity of ophthalmic and mental pathology was considered, as well as factors contributing to the progression of these diseases.
Clinical and social aspects of the quality of life in patients with Parkinson’s disease
Authors: Kopylova Liliya I. , Tappakhov Alexey A. , Nikolaeva Tatiana Ya. , Popova Tatiana E.
Published: July 2023

Parkinsons disease (PD) is an age-related neurodegenerative disease associated with the loss of dopamine-producing neurons in the substantia nigra. The disease is manifested by motor disorders and a variety of non-motor symptoms (NMS). NMS may reduce the quality of life (QoL) of people with Parkinsons disease (PD) more than motor manifestations, but their ultimate contribution has not been fully established.
AIM. To determine the impact of motor, cognitive and affective disorders and social factors on the quality of life of patients with PD in the Republic of Sakha (Yakutia).
MATERIAL AND METHODS. The study included 35 patients with PD, HoehnYahr stage 13 (60% women and 40% men), mean age 64.42.0 years. We used scales: UPDRS, MoCA, HADS, NMSQuest, Epward Sleepiness Scale, PDQ39. The analysis of clinical signs and social factors in the studied group of patients was carried out.
RESULTS. The decrease in QoL was moderately associated with disease stage (r=0.56, p=0.009), the severity of motor manifestations (r=0.65, p 0.001) and the total number of NMS (r=0.46, p=0.008). Age and disease duration did not affect on QoL. The decrease in QoL was influenced by the presence of depression (r=0.83, p 0.001), anxiety (r=0.69, p 0.001) and cognitive decline (r=0.46, p=0.008). Low levels of QoL were found in individual PD patients and in people with disabilities. QoL was not influenced by ethnicity, gender, employment or education. Three groups of patients with PD were identified: those with mild, moderate and severe decrease in QoL. Their clinical and social portraits are presented.
CONCLUSION. The dependence of the quality of life of patients with PD on the form of the disease, the stage of the disease, the severity of depression, social factors has been demonstrated, which requires attention not only from neurologists, but also from psychotherapists and social workers.
Anorexia nervosa and bulimia nervosa: are these diseases really antipodes?
Authors: Sivolap Yury P. , Portnova Anna A.
Published: July 2023

Anorexia nervosa and bulimia nervosa are the main forms of eating disorders that characterized by both obvious similarities and certain differences between each other. The commonality of the two disorders is determined by the predominant occurrence in adolescent and young women, deterioration of physical health, significant psychiatric comorbidity and high suicidal risk. Psychotherapy is the principal treatment for both anorexia nervosa and bulimia nervosa. At the same time, unlike anorexia nervosa, the pharmacological agents with proven clinical efficacy for the treatment of bulimia nervosa exist. Patients with bulimia nervosa are more motivated and adherent to treatment.
World Kidney Day – 2023: kidney health for all — preparing for the unexpected, supporting the vulnerable
Authors: Savenkova Nadezhda D. , Grigoreva Olga P. , Batrakov Denis D. , Petrakova Anna V.
Published: July 2023

The article presents the history of World Kidney Day 20062023. The World Kidney Day, which started in 2006, has become an annual successful initiative of the International Society of Nephrologists, the International Federation of Kidney Foundations to inform the world community and politicians, healthcare about the importance of kidneys for general health, to raise awareness about the significance and consequences of congenital, hereditary and acquired kidney diseases, chronic kidney disease, to adopt a strategy, aimed at reducing the frequency, severity and impact of kidney diseases on health and life. The global nature of the problem of kidney disease in children and adults is evidenced by the fact that in 2011 the Political Declaration on Non-infectious diseases, approved at the summit of the World Healthcare Organization, included kidney disease under paragraph 19. Chronic kidney disease is the 6th cause of death in the world. The annual campaign of World Kidney Day 20062023 poses medical and socio-economic problems of global importance and reminds that kidney diseases affecting children and adults are common, dangerous and curable. World Kidney Day 2023, under the motto: Kidney Health for all preparedness for the unexpected, support for the vulnerable discusses the impact of disasters, in particular the COVID-19 pandemic, on the provision of specialized nephrological care to the population and its resources around the world.
Features of the microbial landscape of the stomach in children, feeding through the gastrostomy or nasogastric tube
Authors: Kuznetsova Yuliya V. , Zavyalova Anna N. , Lisovskii Oleg V. , Gavshchuk Maxim V. , Al-Hares Milad M. , Dudurich Vasilisa V. , Pak Alexandr A.
Published: July 2023

BACKGROUND: In children with dysphagia, an increase in body weight is observed after the placement of a feeding tube, however, subsequently, a regression of body weight is noted, symptoms of an erosive and ulcerative lesion of the gastrointestinal tract appear.
AIM: To identify the features of the gastric microbiome in children fed through a gastrostomy or a tube.
MATERIALS AND METHODS: A study of aspirates of gastric contents in 21 patients was carried out using metagenomic sequencing. The participants were divided into 2 groups: group 1 11 children fed through the gastrostomy for less than 1 year; group 2 10 children, fed through the gastrostomy for more than 1 year.
RESULTS: In group 1, from 8 to 19 phyla were identified, median 12.0. In the second group from 4 to 13, median 7.5, the differences are statistically significant (p 0.05). The samples of both groups were dominated by the phyla Firmicutes, Proteobacteria, Bacteroidota, Actinobacteria, Fusobacteria. The number of representatives of the Bacteroidia and Fusobacteriia classes was significantly reduced in patients with long-term nutrition through the gastrostomy. At the same time, a small number of classes were observed in patients with a gastrostomy in the stomach for about 80 months, as well as in patients with identified gastric pathology. There were about 66 genera for each specimen. At the same time, in children fed through a gastrostomy for less than 1 year, the median is 69.5 OTU. In children fed through a gastrostomy for more than 1 year, even with its regular replacement, the median is significantly less 41 OTU. A significant decrease in microbial biodiversity was revealed with an increase in the standing time of the gastrostomy, the median value of the Shannon index in group 1 was 1.95, in group 2 1.69 (p 0.05).
CONCLUSIONS: In patients with a long stay of the feeding tube in the stomach, the number of anti-inflammatory symbionts of the genus Prevotella, Parabacteroides is reduced. The contamination of the stomach with Helicobacter pylori was 50%, which further increased the predisposition of the gastric mucosa to inflammation.
Gestation outcomes in various options of help for pregnant women with Rh-immunization
Authors: Vetrov Vladimir V. , Ivanov Dmitry O. , Reznik Vitaly A. , Romanova Larisa A. , Kurdynko Lyudmila V. , Nikolaev Alexey V. , Sadykova Gulnaz K. , Menshikova Svetlana V. , Ovsyannikov Philip A. , Vyugov Mikhail A. , Avrutskaya Valeria V. , Vladimirova Natalia Yu. , Chermnykh Svetlana V. , Zheleznaya Anna A. , Koroteev Alexander L. , Вarinov Vladislav A.
Published: July 2023

BACKGROUND: To date, several options for helping pregnant women with rhesus immunization are known: (a) active tactics in carrying out methods of efferent therapy in the form of basic operations (plasmapheresis, hemosorption) in combination with adjuvant methods (immunoglobulin, blood photomodification with ultraviolet, laser beams, ozone therapy) to pregnant women; (b) wait-and-see active tactics with observation of the pregnant woman, followed by intrauterine intravascular transfusions of washed donor red blood cells; (c) mixed active tactics with a sequential combination, alternation of these methods. In Russia, only option 2 with fetal transfusions of washed donor red blood cells is accepted as the basis and paid for. The objective of the study is to conduct a comparative analysis of pregnancy outcomes in women with rhesus immunization using different management options.
MATERIALS AND METHODS: A total of 392 women were followed up at seven different institutions in Russia and at the Donetsk Center for Maternal and Child Health (DNR), of whom 345 pregnant women (Group 1) received efferent therapy, 33 women (Group 2) had fetuses intrauterine bypass surgery, and 14 pregnant women (Group 3) had mixed efferent therapy and fetal PEEP bypass surgery.
RESULTS: The analysis showed that the most favorable results for the main clinical indicators (premature, operative delivery, fetal hypoxia at birth, etc.) were in Group 1 and 3 women, in which the perinatal mortality was 14.5/1000 and 0/1000, respectively, which was significantly lower than in Group 2 (176.5/1000). It was also found that in Groups 2 and 3 women, the mean intervals between repeated transfusions of washed donor red blood cells were 8.8 0.2 and 21.4 3.8 days (p 0.01), which may be explained by the detoxifying effect of efferent therapy methods, preservation of fetal red blood cells and transfused donor red blood cells to the fetus with prolonged gestation and obtaining healthier and more viable progeny.
CONCLUSIONS: 1. Severe Rh conflict is a manifestation of a syndrome of systemic effects of aggressive metabolites of specific and nonspecific nature. 2. The etiopathogenetic measure in the prevention and treatment of HDF/HDN in rhesus conflict is efferent therapy methods for the mother, and transfusion of washed donor rhesus-negative red blood cells to the fetus is effective, but a temporary, palliative measure, as is the case in multiple organ failure. 3. In the treatment protocols, efferent therapy methods must be present to prevent fetal red cell destruction and, equally importantly, to prevent destruction of Rh-negative donor red cells transfused to the fetus.
Features of modern monitoring of the condition of adolescents with asthma
Authors: Nesterenko Zoia V. , Lagno Olga V.
Published: July 2023

The article reviews the literature, including current data of domestic and foreign researchers on the features of the clinical course, the difficulties of diagnosing and monitoring adolescents with asthma due to the mild severity of symptoms, psycho-emotional characteristics of this age, the difficulty of forming adherence to therapy, underestimating ones condition, difficulties in communication with the doctor, parents. Taking into account the specific adolescent characteristics, when drawing up a therapeutic program by a specialist, it is necessary to take into account the lifestyle of a teenager, his needs, which will help to ensure monitoring of the quality of therapy, the formation of adherence to treatment, and the prevention of disease progression. Insufficient control of asthma symptoms necessitates the improvement of medical care for adolescent patients. One of the modern directions in this area is the use of remote telecommunication and information technologies, which are readily and successfully mastered by adolescents, which can significantly improve the quality of observation, the level of adherence and control the process of clinical development of asthma.
PIEZO2 gene and its role in the development of distal arthrogryposis: A literature review
Authors: Chernyavskaya-Haukka Varvara V. , Agranovich Olga E.
Published: July 2023

BACKGROUND:PIEZO1 and PIEZO2 are mechanosensitive ion channel proteins; in humans, they are encoded by genes with identical names. PIEZO proteins convert mechanical signals into biochemical cellular responses following transduction. Recent data highlight the importance of this family of ion channel proteins in the regulation of physiological processes; however, many mechanisms remain unknown. Modern studies have proven thatPIEZO2mutations lead to the development of various forms of distal arthrogryposis.
AIM:To analyze publications containing information onPIEZO2gene and its role in the development of distal forms of arthrogryposis.
MATERIALS AND METHODS:This study analyzed the results ofaliterature search in the open scientific literature databases of PubMed, Cochrane Library, and eLibrary. Consequently, 40 foreign, and domestic scientific sources were extracted from 1969 to 2022.
RESULTS:This study showed the relationship betweenPIEZO2mutations and the development of the distal forms of arthrogryposis. The study also presented the types of distal arthrogryposis and their clinical manifestations depending on the mutation of this gene.PIEZO2mutations with decreased function cause distal arthrogryposis with impaired proprioception and taction (autosomal recessive type of inheritance).PIEZO2mutations with gain-of-function cause distal arthrogryposis of types 3 and 5 (autosomal dominant inheritance).
CONCLUSIONS:Anintegrated approach to the diagnosis and molecular genetic study will allow us to choose the best techniques and treatment of patients with this pathology. The results are useful for doctors of various specialties.