bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural and Mechanical Investigation of Class I Biomimetic Composite Dental Filling by X-ray Computed Tomography, Scanning Electron Microscopy, and Microtensile Bond Strength Testing
Authors: Borhy Levente , Farkas Péter Zoltán , Leveles Borbála , Kemény Alexandra , Volom András , Varbai Balázs
Published: April 2023

Nowadays, short fiber-reinforced composites are broadly used in modern restorative dentistry. The tensile strength, Young's modulus, density, and polymerization shrinkage of these materials are developed to mimic the original teeth tissue best. The shrinkage, however, will occur during any polymerization process, which can cause residual stress and gap formation between the tooth and the filling. These can lead to the propagation of cracks, reduction in the adhesive bond strength, or even cause separation in the restoration. During this research, a biomimetic dental restoration was created on a surgically removed third molar with EverX short-fiber reinforced dental composite by bulk-filling technique. The restored tooth sample was examined by X-ray computed tomography to obtain a 3D image of the whole restoration. The volume of the used adhesive, the material discontinuities, and internal cavities were determined. A cut-out slice was further investigated by scanning electron microscopy to examine the adhesive layer thickness, the gap formation, and the quality of the filling. Finally, microtensile specimens were machined to evaluate the bond strength between the tooth dentin and the filling material.
Organizing meaningful leisure time within the context of ecological education: The experience of Donetsk Republican Library for Young Adults
Authors:   Donetsk Republican Library for Young Adults, Nekrasova Svetlana V.
Published: April 2023

The experience of Donetsk Republican Library for Young Adult in organizing mass events in ecological education of teenagers and young adults is discussed. The «Home» Library Fest of Ecology and Healthy Living and events held by Atom Science Club are reviewed. The findings of quiz on the readiness of the young people to act to protect environment are published.
«Altay is my beautiful Motherland…»
Authors:   Gonokhovo Rural Library, Potrnyagina Olga N.
Published: April 2023

The problems of ecological education of children and teenagers are discussed; the significance of the education for the future of our planet is emphasized. The author summarizes the accumulated experience and reviews efficient methods of ecological education. Certain practical efforts are also discussed.
Ecological and environmental education and ecological awareness in the municipal library
Authors:   Dubna University, Savvateeva Olga A.
Published: April 2023

The results of 3-year joint efforts of Ecology and Earth Sciences Chair and Levoberezhye Municipal Library in ecological education are discussed. Within the core project EcoKnowledge, ecological lessons for schoolchildren and students, ecological quests, actions and exhibitions are held. The project was initiated in 2019. In the recent year, the project «SDGs through the students eyes» has been attracting attention of the visitors of the library’s mass media pages and presenting current information on sustainable development goals.
Organizing the conference «Innovations and green technologies»
Authors:   Samara Regional Universal Scientific Library, Yudintseva Olga I.
Published: April 2023

The experience of Samara Regional Universal Scientific Library in organizing the conference «Innovations and green technologies» in partnership with the regional universities, is discussed.
The library’s awareness and presentation of its collections in art industries
Authors:   V. Mayakovsky Territorial Library for the Blind and Visually Impaired, Zakharova Ekaterina S.
Published: April 2023

The practical aspects of library development in the times of creative economy, are examined. The key vectors of the national cultural policy are discussed within the context of advancing creative industries. The structure of library resources to contribute to the creative economy, is outlined. The potential of Stavropol Territorial Library for the Blind as the site for creative communities is revealed.
Efectos colaterales del tramadol versus paracetamol durante la labor de parto en gestantes atendidas en el Hospital de Especialidades José Carrasco Arteaga, periodo 2014-2019
Authors: Cobos Tobar Juana Karina , Corella Verdugo Nadia Mireya
Published: April 2023

Introducción: el parto representa la forma más severa de dolor experimentado en la vida de una mujer, su manejo adecuado se asocia con una experiencia satisfactoria. Objetivo: determinar los efectos colaterales del tramadol versus paracetamol durante la labor de parto en gestantes atendidas en el Hospital de especialidades José Carrasco Arteaga, año 2014-2019. Metodología: se realizó un estudio descriptivo transversal, se recolectó información de 216 historias clínicas electrónicas del sistema AS-400. La información se registró en una ficha de recolección de datos elaborada por la investigadora Juana Cobos, y posteriormente en el programa estadístico SPSS v. 15. Resultados: la edad media de la población materna fue 30 años de edad, (94%),  el 66,2% fue multípara, el 94% presentó controles prenatales adecuados, la duración promedio de la labor de parto fue de 8 a 17 horas en primíparas (53,12%) y de 5 a 11 horas en multíparas (50,3%), el tramadol se administró en el 42,59% y produjo efectos colaterales como náusea (57,61%), cefalea (47,83%), vómito (9,78) e insomnio (9,78), la dosis habitual de tramadol fue de 100mg. vía intramuscular (95,65%); el paracetamol produjo efectos adversos con menor frecuencia y se prescribió 1000mg. vía intravenosa en un 65,6%, las complicaciones perinatales como estado fetal no tranquilizador, taquicardia fetal y otras se observaron con mayor frecuencia con tramadol. Conclusión: Finalmente, el tramadol ocasionó más efectos adversos que el paracetamol al administrase durante el trabajo de parto. Área de estudio: ginecología
Indicadores sostenibles urbanos para la ciudad de Cuenca: la gestión de aguas residuales
Authors: Peláez Ochoa Christian Paúl , Quesada Molina Juan Felipe
Published: April 2023

Introducción: Actualmente la ciudad de Cuenca atraviesa por un continuo crecimiento demográfico que ha incrementado la demanda de infraestructura de servicios básicos, considerando este antecedente es importante conocer qué indicadores intervienen en la gestión de aguas residuales, ello considerando la importancia del cuidado de los ríos. El objetivo principal de este trabajo fue: crear indicadores sostenibles para la gestión de aguas residuales en la ciudad de Cuenca. El estudio fue de tipo exploratoria-descriptiva de nivel exploratorio, con enfoque mixto; en lo cualitativo se realizó una búsqueda bibliográfica, para ello se recurrió a las bibliotecas y documentos tanto físicos como digitales de literatura científica existente, con énfasis en: Guía Metodológica-Iniciativa Ciudades Emergentes y Sostenibles (BID), ISO 37120 Desarrollo sostenible de las comunidades, Objetivo 6 de Desarrollo Sostenible, LEED v4.1 Ciudades y comunidades, Comunidades BREEAM Manual Técnico, Indicadores y Metas Oficiales del ODM7; en lo cuantitativo se aplicó un modelo matemático y estadístico para la construcción de indicadores, mismos que fueron sometidos a un juicio de expertos, para su validez se consideró valores mayores a 0.70 de aceptación de acuerdo a los niveles de referencia internacionales. Los resultados del estudio dieron a conocer que los indicadores sostenibles fueron: porcentaje de hogares con conexión domiciliaria al sistema de alcantarillado que obtuvo una calificación de 0.90, porcentaje de aguas residuales tratadas de conformidad con las normas nacionales con una calificación de 0.80.
Indicadores de sostenibilidad urbana para la ciudad de Cuenca: evaluación de materiales de bajo consumo energético en la construcción
Authors: Chicaiza Lojano Jaime Rolando , Quesada Molina Juan Felipe
Published: April 2023

Introducción. El desarrollo sostenible dentro de las ciudades en los últimos años es un tema de total responsabilidad para quienes habitamos el planeta, actores de la construcción también se han sumado para proponer alternativas en base a investigaciones sobre materiales que se emplean en esta actividad; sin generar un gran impacto en el medio ambiente e inconvenientes o escasez para futuras generaciones. En el presente proyecto aplicaremos una metodología de investigación no experimental descriptiva y analítica para la búsqueda y selección de indicadores idóneos respecto a materiales de bajo consumo energético en la construcción, para finalmente dar paso a la formación de un marco de estos que logren ser aplicados dentro de la ciudad de Cuenca y vayan acorde a su realidad. Objetivo. Determinar indicadores de sostenibilidad para materiales de bajo consumo energético en la construcción que aporten a la sostenibilidad de la ciudad de Cuenca. Metodología. Para esto, la metodología aplicada se centra en una investigación no experimental, descriptiva y analítica; dentro de ella se enmarca la búsqueda y selección de indicadores idóneos para la ciudad de Cuenca respecto a materiales de bajo consumo energético en la construcción, esto servirá para el conocimiento y alcance de los objetivos planteados, a partir de esto se establecen las etapas que se detallan a continuación: Revisión bibliográfica, consiste en la exploración de cada guía metodológica y herramientas de evaluación sobre indicadores de sostenibilidad para las ciudades; Clasificación, una vez analizada la documentación se obtuvieron los indicadores relacionados al tema en discusión; Análisis, qué indicadores se relacionan con el tema, debido al grado de repetición entre las guías y las herramientas de evaluación revisadas; Homologación, considerado como la repetición de indicadores en las guías y herramientas de evaluación y por último; Definición, acorde al juicio de expertos se definirán los indicadores idóneos para la evaluación de materiales de construcción sustentable. Resultados. Con la información recolectada en el presente proyecto se presenta un marco de indicadores de sostenibilidad urbana que están relacionados con materiales de bajo consumo energético en la construcción para la ciudad de Cuenca, estos se identificaron mediante la revisión de las distintas guías metodológicas y herramientas de evaluación, tomando como punto de inicio un contexto internacional para llevarlo hacia niveles locales. Conclusión. No existe una definición estricta sobre los indicadores que tienen que ver con materiales de bajo consumo energético en la construcción; sin embargo, se logró obtener información que corresponde al desarrollo sostenible en este ámbito y área de la construcción y se creó un marco con cinco indicadores que se relacionan con el tema. Área de estudio: arquitectura.
Patterns of injury and death in mass casualty incidents from 2013 to 2018 in Mogadishu, Somalia Mass casualty incidents in Mogadishu, Somalia
Authors: Nor Mahad Abdullahi , Sonmez Recep Ercin , Hassan Mohamed Yusuf , Ozsoy Mehmet Sait , Alimoglu Orhan
Published: April 2023

Objective: Mass casualty incidents (MCI)s are a serious threat to public health in Mogadishu, Somalia. The present study aims to demonstrate the patterns of injury and clinical outcomes in MCIs in Mogadishu, Somalia.
Methods: This is a retrospective, cross-sectional analysis of clinical data retrieved from patients involved in MCIs between 2013 and 2018 in Mogadishu, Somalia. Patient demographics were statistically analyzed with the anatomical site of injury, mechanism, and types of injury to find any meaningful association among each other in terms of clinical outcomes.
Results: Four hundred (M/F: 62%/38%) cases were included in the present study. There was a significant association between the mechanism of injury and incidence of mortality (95% CI = 0.028-6.65) (p=0.02). Another significant association found was between the clinical presentation of injury and mortality rate of which the presence of external/or internal bleeding was highly associated with death (95% CI = 0.640- 3.163; OR:1.423) (p=0.02).
Conclusion: Prompt precautions should be taken by improving awareness of the public through educational programs, preparing campaigns in coordination with the ministry of health, and influencing the power of the media should be used to reach everyone in the society.
Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 323-328
Mental Health Training Programs for Community Pharmacists in Low Middle-income Countries: A Systematic Review
Authors: Febrinasari Nisa , Kristina Susi Ari , Widayanti Anna Wahyuni , Prabandari Yayi Suryo , Satibi Satibi
Published: April 2023

Objective: This review aimed to explore the potential approachto continuing education and training the community pharmacists to equip them to support mental health consumers in lowmiddle- income countries.
Materials and Methods: A systematic search strategy was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Search terms related to mental health, training program, and community pharmacist were used in three major databases (i.e.,PubMed, Science Direct, and Scopus), retrieving a total of 5575 articles. Ten studies met the inclusion criteria.
Results and Discussion: There was evidence that shortduration delivery and non-direct contact training with patient diagnosed with mental illness (consumer educator or peer-level-educator) have the same effect as long training delivery and direct contact intervention. Consumer educator or peer-level-educator in mental health training programs are key factors to improved mental health knowledge, attitudes, and pharmaceutical care service of community pharmacists.
Conclusion: Flexible nondirected delivery methods using video footage of expert and mental health patients were preferred for a low-cost program accessible to a large community pharmacy workforce which can be applicable in developing countries. However, there is an urgent need for further studies to clarify actual changes in the attitude of and daily service by pharmacists after participating in a mental health training program.
Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 284-296
Readiness for emergencies and disasters, and health competencies among people with epilepsy
Authors: Yılmazel Gulay
Published: April 2023

Objective: Epilepsy, one of the chronic diseases with a substantial share in the global burden of disease, can be brought under control with proper disease management. A part of disease management is preparedness for emergencies and disasters. Health competence is a protective mechanism in developing behavior and readiness for emergencies and disasters. This study aims to determine the relationship between preparedness against emergencies and disasters and health literacy competencies in people with epilepsy.
Methods: The study was carried out with 270 epilepsy patients, 18 years of age and older, living in Turkey’s Central Black Sea Region between April and May 2022. The questionnaire form included socio-demographic characteristics, health behaviors related to disease management (smoking use, regular exercise, regular use of drugs, etc.), and emergency and disaster preparedness behaviors. The disaster preparedness of the participants was evaluated through the “Disaster Preparedness Scale,” and their health competence skills were evaluated through the “Health Literacy Scale-Short Form.
Results: The median HLS-SF score was 30, and the median disaster preparedness score was 31. More than two-thirds of the participants knew the trigger of the seizures and had at least three days of medication with them when they left home. Only 6.7% of the participants stated that they had a medical alert wrist/card, and 37,4% stated that they know the emergency call number they need to call in case of any emergency. The median disaster preparedness scores varied by gender (p<0,01) and were 32 for women and 31 for men. The median disaster preparedness score was 31 for married, and it was found to be significantly higher than for singles (p<0.05). The disaster preparedness score was higher among those who lived in the city/district center (p<0.01). The median disaster preparedness score was 31 among those with regular physical activity, different chronic diseases, and who took their medications regularly, significantly higher than the other groups (p<0.000). There was a significant positive correlation between the individuals’ age, sleep duration, epilepsy duration, HLS-SF, and disaster preparedness levels (p<0.05).
Conclusions:People with epilepsy had some gaps in preparedness against emergencies and disasters and also health competence. During a disaster and emergency, medically vulnerable individuals with epilepsy must be able to meet their particular needs on their own. The way to develop emergency and disaster preparedness behaviors is to increase health competencies.
Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 341-347
The Pre-Nosological Diagnostics of Integral Health of a University Professor
Authors: Myrzabayev Amanay , Kabdolla Yerbol , Tnimova Gulbagiza , Sokolova Galina , Bodeyev Marat , Sivolobova Olga , Kuznetsova Lyudmila
Published: April 2023

Objective: In accordance with the WHO, health is defined as integral, consisting of physical, mental, and social components that are closely interrelated and reliably correlated. Thus, the health condition of 168 university professors (39 men and 129 women) was examined.
Materials and methods: They were divided by age into 3 groups (group 1 – 23-39 years old, group 2 – 40-59 years old, group 3 – 60 and above). The physiological rates were evaluated during the autumn term, and the questionnaire was conducted during the spring term (2018- 2019). Professional motivation was chosen as an indicator of the social health of a professor (the method of K. Zamfir in the modification of A. Rean). The mental health of the survey participants was assessed by the level of occupational burnout (the method of K. Maslach and S. Jackson modified by N.E. Vodopyanova).
Results and Discussion: The level of physical health was determined by estimating the biological age (BA) and comparing it with the standard population rate (the express method of V.P. Voitenko). The motivation of the professors is complex and expressed in different ways. It directly depends on gender and work experience. Professors of all ages are more or less susceptible to the syndrome of occupational burnout.
Conclusion: According to the BA rate, the organism of young men strongly reacts to unfavorable factors of the educational process, but it adapts with age and work experience. The organism of women has a similar dynamic, but less negative reaction. In addition, the male aging is 1.6 times more accelerated than female aging. The methodological approach used provides a big picture of the integral health of a university professor.
Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 432-441
Cecal volvulus with intestinal malrotation: a rare cause of bowel obstruction
Authors: Hajri Mohamed , Talbi Ghofran , Moula Kais Abdel , Guizan Rami , Ferjaoui Wael , Mestiri Hafedh , Bayar Rached , Farhat Leila Ben
Published: April 2023

Introduction:Cecal volvulus is a rare cause of acute abdomen in adults. It accounts for less than 1% of intestinal obstructions and 25-30% of cases of colonic volvulus. Congenital intestinal malrotation is a complex disorder due to incomplete or faulty rotation and fixation of the gut during the fetal life.Cecal volvulus associated with intestinal malrotation is a very rare presentation. Over 16 cases were reported in the literature.
Case report:A 44-year-old man with no medical history, presented to the emergency department with a 2-day history of abdominal pain and bloating. On clinical examination, the abdomen was distended and tympanic to percussion, with diffuse abdominal tenderness. Abdominal X-ray (standing) showed a distended large intestine with an airfluid colonic level. CT scan showed a markedly dilated cecum measuring up to 14 cm, which were located in the left hypochondrium. A “whirl sign” and a superior mesenteric pedicle swirl were also noted. Emergency surgery was performed. Intraoperative exploration revealed a cecal volvulus with a largely distended hypermobile cecum located in the left hypochondrium, with preischemic signs within its wall. All the small gut was right-sided and the large gut left-sided, suggestive of mesenterium commune and intestinal malrotation. A right hemicolectomy withileo-transverse anastomosis was done. The postoperative course was uneventful. The patient is on regular follow up and is doing well.
Conclusion:We describe a rare case of surgical management of cecal volvulus associated with intestinal malrotation in a middle-aged patient with no medical history. This case highlights the importance of early diagnosis by physical examination and radiological findings to prevent serious complications. Emergent surgery was the key to this successful management and surgical resection could offer better results with lesser recurrence rate.
Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 445-448
Face Mask: The New Norm That Becomes The New Anatomy
Authors: Saniasiaya Jeyasakthy , Mohamad Irfan
Published: April 2023

Abstract not available
Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 454-456
Postoperative Complications after Surgical Management of Mandibular Angle Fracture
Authors: Akter Sharmin , Ashrafi Zobaida , Manira Sirajum , Rahman Mohammad Asifur , Rashid Md Harun Ur
Published: April 2023

Introductions: Mandibular angle fractures represent a high percentage and an important clinical challenge because of their treatment pattern and the highest postsurgical complication rate among all mandibular fractures.
Materials and methods: The objectives of this cross-sectional observational study were to observe the postoperative complications after surgical management of a mandibular angle fracture and to facilitate early detection of complications and reduction of patients’ morbidity. This study was carried out among forty patients with mandibular angle fractures who were managed by open reduction and internal fixation by miniplate osteosynthesis. All the study patients were evaluated clinically pre- and postoperatively for various parameters at the 1st week, 2nd week, 1st month, and 4th month. Radiographs (OPG, PA skull, lateral skull, and CT scan of the oral and maxillofacial region) were taken pre- and postoperatively to assess complications. The infection was detected by culture and a sensitivity test. Nerve injury was evaluated by the “tactile test”, the brush directional stroke test by using a ’00’ camel hair brush, and the pinprick test performed by using a sterile 27-gauge syringe needle. Occlusion and chewing were evaluated postoperatively according to the Treatment Scoring System developed by V. Uglesic in 1993. The data was analyzed using the SPSS version 20 statistical software.
Results: In this study, most of the patients (85%) were male and the mean age was 24.5 years. In the fracture line third molar was present in 55% cases. The most common complication of this study shows postoperative nerve injury 30% cases. Infection in 10% cases, malocclusion in 7.5% cases. Slight restricted mouth opening in 5% cases. Other complications such as malunion,, delayed union, and non-union were absent.
Conclusion: The most common complication after surgery is nerve injury along with infection and malocclusion. A careful preoperative assessment, early surgical intervention, meticulous surgical technique, postoperative care and appropriate rehabilitation are the main concern to prevent neurological and other complications. 
Update Dent. Coll. j: 2023; 13(1): 9-13
Student's Perceptions Regarding e-Learning during Covid-19 at Private Medical and Dental Colleges of Bangladesh
Authors: Rafique Taslima , Molla Golam Morshed , Liza Mowshomi Mannan , Ahmed Asma , Nath Sujan Kanti , Siddika Aeysha , Noor Ashek Elahi , Hossain Chowdhury Mohammad Tawfique
Published: April 2023

Background: Covid-19 pandemic era introduce E-learning process in education system all over the world include medical science. Repeated researches should be conducted to explore the limitations and combat with the challenges of the E-learning process as well as find out the methods of suitable medical education system for future.
Method: A cross-sectional study was performed among 334 MBBS (n = 114, 34.3%) and BDS (n = 218; 65.7%) students of four selected private Medical and Dental colleges in Bangladesh to reveal the perception of the students towards E-learning during the COVID-19 outbreak. Data was collected through an online platform using the snowball sampling technique in between October 2021 to March 2022.
Result: Most of the participants use mobile phones (n = 308, 92.8%) and Wi-Fi connections (n = 153, 46.1%) for online classes. Majority of the participants had negative perception regarding E-learning. In addition, most of the participants responded that, E-learning is not better than traditional teaching (n = 292, 88%), the quality of E-learning is not satisfactory (n = 198, 59.6%), the usefulness of E-teaching regarding clinical and practical demonstrations is not satisfactory (n = 284, 85.5%), and the blend of E-learning will be beneficial in the future (n = 224, 67.5%), where female students (p = 0.049) and BDS students (p = 0.003) gave a more positive response in comparison to male students and MBBS students. BDS students gave more positive response about the satisfaction in quality of E-learning rather than MBBS students (p= 0.003). MBBS students significantly responded more negatively than did BDS students (p = 0.003) regarding student-teacher interactions during the e-learning process.
Conclusion: Students adjusted themselves with the E-learning techniques but they believe that blending of E-learning, which combines both classroom and distance learning will be beneficial for them in future. The COVID-19 pandemic affects future approaches to teaching methodologies and changes to the medical education system.
Update Dent. Coll. j: 2023; 13(1): 3-8
A checklist of Indian Epipaschiinae (Lepidoptera, Pyraloidea, Pyralidae)
Authors: Tanagal Venkatesh , Murthy M. Shankara , Reddy P. Maheswara
Published: April 2023

A systematic checklist for the species of Epipaschiinae (listed alphabetically) occurring in India, listing 80 species under 18 genera is presented. The report accounted for 10.85 per cent of species and 19.15 per cent of genera from India as compared to global record (737 described species under 94 genera). Further, the valid name, type genus, type species, type locality, synonyms, host range and distribution of each species under each genus are provided.
Morphological and biochemical basis of resistance against the pod borers Maruca vitrata F. and Helicoverpa armigera Hübner in cowpea
Authors: Muchhadiya D.V. , Patel J.J. , Garaniya N.H. , Patel D.R.
Published: April 2023

For determination of morphological and biochemical basis of resistance in cowpea against the pod borers (Maruca vitrata F. and Helicoverpa armigera Hübner), ten cowpea cultivars were evaluated during kharif 2017 and 2018. Results revealed that cultivars having indeterminate growth, yellow flower, light green and short pods as well as long peduncle recorded lower pod borer population. Correlation between different plant morphological characters and the larval population were found non-significant. The cultivars having low protein, high phenol and low total soluble sugars in flowers and immature pods recorded lower the larval population. The correlation between biochemical components of flowers and larval population were found to be non-significant. Biochemical components of immature pods revealed that phenol exhibited significant negative relationship with larval population, whereas, correlation of total soluble sugars of immature pods exhibited significant positive association with larval population. Among the cultivars screened, GC-6 and GC-1605 were found to be consistently resistant based on different morphological and biochemical factors and pod borer infestation. Relatively GC-1609, GC-1611 and GC-2 showed lesser pod borer infestation. GC-1606 was found to be highly susceptible.
Trapping analysis of ants (Hymenoptera, Formicidae) in Kurunthamalai, Coimbatore, Tamil Nadu, India
Authors: Sornapriya J. , Lekeshmenaswamy M.
Published: April 2023

Ant species were collected from three different methods bait trapping (BTM), all-out search method (AOSM), and pitfall trapping method (PTM) method. A total of 14 species belonging to the eight genera and four subfamilies are listed in the Palamalai region. Monomorium indicum, Solenopsis germinata, Trichomyrmex crinieceps, Trichonymex glaber, Camponotus mendax, C. guticollis, C. irritans, C. parius, C. rufoglaucus, Oecophylla smaragdina,,Diacamma indicum, Leptogenys chinensis, Tetraponera  rufonigra and Tetraponera spp were reported. Shannon Wiener, Simpson diversity, Dominance, Evenness, Menhinick, Margalef, Fisher alpha and Berger- Parker calculations and diversity richness are reported.
First record of Ahmaditermes emersoni Maiti (Isoptera, Termitidae, Nasutitermitinae) from Meghalaya, India
Authors: Das Khirod Sankar , Choudhury Sudipta
Published: April 2023

The nasutiform termite species Ahmaditermes emersoni Maiti is reported from Meghalaya, India for the first time. All the studied samples of the species were collected from betel nut plantation in Mawlynnong area of East Khasi Hill district of the state. Morphology of both the soldier and worker castes of the species was studied in detail and the identification was done based on their morphological characteristics. Redescription of morphology and revision of morphometric of both the soldier and worker castes are provided in this article. With the record of this species, the genus Ahmaditermes is also reported for the first time from the state.
Memorias del Congreso Internacional Estudiantil Ética, Universidad y Sociedad
Authors:   Universidad del Azuay, Quito-Tello Paula , Arichávala-Zúñiga Alfredo ,   Universidad del Azuay, Pauta-Pesantez Rafael ,   Universidad del Azuay, Córdova-Serrano María Eliza ,   Universidad del Azuay, Abad-Fernández-de-Córdova Angélica ,   Universidad del Azuay, Gavilanez Liceth ,   Universidad del Azuay, Torres-Barzallo María Emilia ,   Universidad del Azuay
Published: April 2023

Los estudiantes de la Universidad del Azuay, siempre han tenido roles importantes en la vida académica institucional, pero en esta ocasión tuvieron el rol protagónico. Absoluto. Pues si bien el Congreso forma parte de las actividades del Programa de Ética de la Universidad, y tiene un espacio específico en esa planificación general y recibió por lo tanto el respaldo de autoridades, profesores y personal administrativo institucional, su participación como organizadores, ponentes y responsables de los últimos tramos que permiten llegar a esta anhelada publicación de sus Memorias, fue insustituible y decisiva. Ellos tienen todo el mérito, pues trabajaron con denuedo desde que se anunció, con un año de anticipación, que se realizaría el evento. Coordinaron con universidades nacionales y extranjeras la presencia de otros jóvenes como ellos, estudiantes de esos centros de educación superior, para que escriban y presenten sus ponencias. Lo hicieron con universidades locales, chilenas, brasileñas, mexicanas y estadounidenses, logrando la participación de veinte y ocho jóvenes en los ejes temáticos arriba mencionados. Organizaron para los estudiantes locales procesos de formación específicos sobre escritura académica, oratoria e investigación científica, que fueron asumidos por profesores de la Universidad del Azuay, con el fin de garantizar la seriedad y calidad del evento. Son los responsables directos de la exitosa realización del Congreso en noviembre de dos mil veinte y uno. Y, lo son, finalmente, de esta publicación que los llena de alegría, sobre todo por el deber cumplido. 276 páginas ISBN: 978-9942-618-22-1 e-ISBN: 978-9942-618-23-8
Budget impact analysis of enzalutamide for the treatment of hormone-sensitive metastatic prostate cancer in Italy
Authors: Fiorentino Francesca , Di Rienzo Paolo
Published: April 2023

Backgroud: After demonstrating additional benefit versus standard of care in ARCHES and ENZAMET studies, enzalutamide was reimbursed in Italy in May 2022 by the National Health Service (NHS) for the treatment of hormone-sensitive metastatic prostate cancer (mHSPC).
Objective: This study estimates the financial impact associated to the introduction of enzalutamide for patients with mHSPC.
Methods: A budget impact model was developed with a dynamic cost calculator approach, in which the impact on subsequent lines of therapy was considered. The analysis considered the NHS perspective and a 3-year time horizon. Included costs were related to drug acquisition and administration, monitoring, patient follow-up and adverse events. Eligible population was estimated based on published literature, real-world data and experts’ opinion while market shares were assessed considering real-world data and assumptions. National tariffs and published literature were considered for unit costs.
Results: Eligible population was estimated at 6,200, 6,206 and 6,212 in years 1, 2 and 3 respectively. The introduction of enzalutamide, considering a progressive increase of market shares of 10%, 18% and 25%, is expected to overall increase NHS healthcare expenditure by € 688 thousands and € 2.6 and € 5.6 million in years 1, 2 and 3 respectively, corresponding on average to 1.55% of the overall prostate cancer expenditure.
Results are robust across one-way sensitivity analyses, while confidential discount agreements of on-patent drugs might significantly impact the estimates.
Conclusion: The introduction of enzalutamide for the treatment of adult patients with mHSPC is expected to increase patients’ health with a moderate impact on costs for the Italian NHS.
Abordagens e recursos fisioterapêuticos no Serviço de Atenção Domiciliar (SAD): revisão integrativa
Authors: Oliveira Daise dos Santos de , Brito José Rafael da Conceição , Ferro Thauan Narciso de Lima , Alves Ahyas Sydcley Santos
Published: April 2023

Este estudo de revisão integrativa teve como objetivo descrever as abordagens e recursos fisioterapêuticos no SAD do Programa Melhor em Casa. A busca dos dados foi realizada nas bases de dados PubMed, Biblioteca virtual em saúde (BVS), Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), SCIELO e Google acadêmico com os descritores: Fisioterapia, Tratamento domiciliar, Serviço de Assistência Domiciliar, Assistência domiciliar, e, utilizando estratégias de combinação dos termos. A triagem dos artigos encontrados foi realizada através da leitura do título, da leitura do resumo, e, ainda em caso de dúvida, o artigo era lido na íntegra e selecionados pelos critérios de inclusão e exclusão. Após a filtragem e análise das publicações, foram selecionados 8 artigos para esta revisão. Evidenciou-se nesta revisão que diversos são os contextos vivenciados na atuação do fisioterapeuta no SAD e diversos são os recursos utilizados por ele, dentro de uma importante atuação dentro da equipe multidisciplinar. Também foi possível levantar os desafios, avanços e potenciais desta atuação com os pacientes e cuidadores domiciliares. O fisioterapeuta no SAD atua no contexto da criança ao idoso, do paciente com necessidades pneumofuncionais ao paciente em cuidados paliativos, com técnicas e recursos sejam manuais, sejam elétricos, sejam cinesioterapêuticos, sejam mecânicos ou orientacionais. Neste cenário, os estudos utilizados e os revisores desta pesquisa apontam para a necessidade de continuação das pesquisas na temática para fortalecimento da prática baseada em evidência.
Pemanfaatan Aplikasi Penangkal Berita Hoaks bagi Perangkat Desa
Authors: Adawia Popon Rabia , Wijayanti Diah , Haryadi Eko , Yuliandari Dewi
Published: April 2023

Berkembangnya ilmu pengetahuan dan teknologi telah mampu memberikan dampak yang cukup signifikan kepada masyarakat khususnya di dalam perolehan informasi yang belum diketahui tingkat kebenarannya. Tujuan dari kegiatan pengabdian masyarakat ini adalah membantu para aparat desa di dalam memahami langkah-langkah menangkal berita yang tidak benar (hoaks). Pengabdian masyarakat dilaksanakan oleh para dosen dan mahasiswa dari Universitas Bina Sarana Informatika selama 2 (dua) hari melalui pelatihan pemanfaatan aplikasi penangkal berita hoaks. Pelaksanaan kegiatan bertempat di Kantor Desa Cikampek dengan peserta para aparat RT, RW dan staf kantor desa. Diharapkan dari kegiatan ini para peserta dapat lebih mengetahui berita yang benar dan hoaks serta bagaimana memahami langkah- langkah untuk menangkal berita hoaks.
Pelatihan untuk Menumbuhkan Semangat Wirausaha untuk Meningkatkan Pendapatan Panti Asuhan Sakinah Depok
Authors: Widyastuti Indria , Widodo Dwiyatmoko Puji , Sugiarti Sugiarti , Putra Atri Nodi Maiza , Setyaningrum A’isyah , Tasliah Siti
Published: April 2023

Kegiatan pengelolaan panti asuhan tentu memerlukan dana. Dana santunan yang didapat baik dari donatur selama ini oleh Pengurus Panti Asuhan Sakinah Depok hanya sekedar digunakan untuk memenuhi kebutuhan operasional dari panti, tanpa ada pemikiran untuk memanfaatkan dana tersebut untuk membuat usaha. Untuk membentuk jiwa wirausaha tentu membutuhkan pengetahuan dan waktu yang cukup, sehingga pada akhirnya akan membangun sikap mental wirausahawan yang baik. Untuk itu beberapa dosen Prodi Akuntansi FEB Universitas Bina Sarana Informatika merencanakan untuk mengadakan kegiatan pengabdian masyarakat berupa pelatihan kewirausahaan bagi pengurus Panti Asuhan Sakinah Depok. Tujuan dari diadakannya pelatihan ini adalah agar pengurus panti asuhan sakinah depok mampu memahami pentingnya pengetahuan kewirausahaan bagi perkembangan ekonomi panti agar bisa semakin mandiri dalam memenuhi segala kebutuhannya. Kegiatan ini juga diikuti oleh anak-anak panti di mana tujuan dari kegiatan pelatihan ini agar anak-anak yang ada di panti juga mampu menumbuhkan kreatifitas dan inovasi yang dimiliki, serta anak-anak panti menyadari bahwa perlu adanya bekal diri untuk menghadapi perkembangan dunia usaha
Psikoedukasi Kemampuan Adaptasi Karyawan melalui Webinar bagi Karyawan yang Menerapkan Sistem Work from Office (WFO) Selama Masa Pandemi Covid-19
Authors: Kusristanti Chandradewi , Arum Dewinta
Published: April 2023

Wabah virus corona atau yang juga dikenal sebagai COVID-19 resmi ditetapkan sebagai pandemi global karena tingkat penyebarannya yang sangat pesat. Adanya wabah COVID-19 tersebut mengharuskan berbagai negara untuk menerapkan protokol kesehatan seperti Pembatasan Sosial Berskala Besar (PBB) ataupun lockdown. Sebagai upaya dalam menghentikan penyebaran virus COVID-19, beberapa perusahan di Indonesia mulai menerapkan sistem Work from Home (WFH) dan Work from Office (WFO). Penerapan sistem kerja tersebut mengharuskan para pekerja untuk bisa beradaptasi atau menyesuaikan diri dengan segala perubahan dan kesulitan yang terjadi di masa pandemi. Dalam hal ini, penulis merancang sebuah psikoedukasi dalam bentuk webinar yang bertujuan untuk meningkatkan pengetahuan dan kemampuan beradaptasi dalam menghadapi perubahan dan tantangan di tempat kerja selama pandemi COVID-19.
Mud and mangroves in Suriname
Authors:   , de Vries Job
Published: April 2023

Mudbanks are pertinent features that can be found along the 1,500-km long coastline of the Guianas. These mostly subtidal banks migrate from the mouth of the Amazon River in Brazil, along the coasts of French Guiana, Suriname and Guyana to the Orinoco Delta in Venezuela. When present the protect the coasts against incoming waves and simultaneously provide a source of sediment for coastal expansion and consequential mangrove colonization. Due to the alternating phases of erosion and expansion, that can last up to 10 – 15 years, is remains difficult to implement long-term coastal management strategies in the Guianas. This is especially true for coastal protection, nature conservation, CO2 storage and the development of agriculture and aquaculture.
The limited accessibility of the coastal zone and the challenge to demarcate mudbanks in satellite observations make it difficult to differentiate between natural changes and those caused by mudbank migration, human interference or the impact of climate (change). Satellite observations offer the potential to improve future predictions, accurately analyse indicators of changes in mangrove forests and timely detect coastline changes on local- to regional scales.
In this thesis a remote-sensing workflow was developed to utilize the spatial and temporal resolution of the complete Landsat satellite data archive since 1986 for the detection of mudbanks and associated coastal changes. This information was used to quantify the effect of mudbanks on local scale for the purpose of coastal management. We show that on average 32 m/yr coastal expansion occurs when mudbanks are present and 4 m/yr of erosion when absent. Large spatial- and temporal variations however highlights the importance variable mudbank footprints, caused by currents and waves, for the duration of coastal protection and natural changes that occur in mangrove forests.
Antibody-based approaches to modulate immune response
Authors:   , Segués Cisteró Aina
Published: April 2023

In context of an increasing interest in immunotherapeutic treatments, the work described in this thesis expands the current knowledge of several potential antibody-based therapeutic approaches. A new development is the use of bispecific antibodies (BsAb). To introduce BsAb, chapter 2 describes the different platforms currently used to generate IgG-like and non-IgG-like BsAbs, as well as the strategies to gain clinical approval for the different BsAbs. A highly selective binding, as can be achieved with BsAbs, could be beneficial to ‘target’ certain cell populations, such as Tregs, against which current treatments appear to be insufficiently specific. Focusing on BsAb-based therapeutic approaches, in chapter 3 we investigate a novel strategy to optimize a T-cell redirecting bispecific antibody. Two Fab x sdAb-Fc, directed against CD3 and EGFR, with different lengths of the hinge region, were compared. The results show that a shorter hinge design improves BsAb-induced anti-tumor activity, induces more effector cell/target cell clustering and activates T cells more efficiently. In addition, we show (chapter 4) how important it is to select the right isotype antibody. In a mouse tumor model, only IgG2a antibodies were found to exert anti-tumor function, achieving a survival rate of approximately 50%. None of the isotypes tested showed a synergistic effect with adoptive T-cell therapy. An increasing interest in the costimulatory receptor TNFR2 in cancer has prompted us to design, generate and produce novel anti-mTNFR2 antibodies (chapter 5). The characterization and different features of these antibodies are described in this chapter, and they could be used as tools in follow-up studies to further investigate i) the role of TNFR2 in cancer, and ii) how TNFR2 targeting with different antibody candidates that either block or activate this receptor could improve immunotherapy. In chapter 6, two anti-mTNFR2 antibodies were selected for assessment of their application in vitro, ex vivo and in vivo, which revealed their capacity to bind to Tregs but also to CD4+ effector T cells.

Taken together, the results presented in this thesis highlight the progress achieved in immunotherapy approaches, with focus on BsAbs and novel strategies to improve cancer treatments. Furthermore, novel anti-mTNFR2 antibodies were developed and featured as useful tools to unravel the role of this receptor in tumor growth.
DEVELOPMENT OF CONSTRUCTION PROJECTS AS A COMPOND AGGREGATED SYSTEM
Authors: POKOLENKO VADYM , BONDAR OLENA , YASCHENKO OLEKSII , YAKYMCHUK IRINA , LATANIUK NATALIIA
Published: April 2023

The article considers development as a modern form of investment activity in the real estate market. Features of development projects are outlined, and problematic issues of designing and implementation of development projects are identified from the point of view of an aggregated system approach, which is using the latest information technologies. Development is also considered within the framework of the urban development ecosystem, which is also a component of the principle of an aggregated system. The practical significance of the study lies in the fact that the main theoretical and methodological provisions can be used both for further theoretical research and in the practical activities of economic entities of the construction complex in order to improve project management and increase the efficiency of construction organizations and urban planning as whole.
Spondyloarthritis: Pathogenesis, Clinical Manifestations, Diagnosis and Management
Authors: del Río-Martínez Pilar S.
Published: April 2023

The term spondyloarthritis (SpA) is used to describe a heterogeneous group of diseases sharing certain characteristics. Traditionally, patients with SpA have been classified in five subgroups: ankylosing spondylitis (AS), psoriatic arthritis, arthritis associated with inflammatory bowel disease (IBD), reactive arthritis, and undifferentiated SpA. The pathogenesis of SpA is still not entirely clear; it is considered to be multifactorial, the result of interaction between genetic risk factors and environmental triggers that lead to activation of autoinflammation and autoimmunity. This group of diseases is characterised by a chronic inflammation in entheses and other anatomical structures, leading to their main clinical features: sacroilitis, enthesitis, and peripheral arthritis. An association with extra-articular manifestations such as psoriasis, uveitis, and IBD is also a distinctive feature of SpA. Several diagnostic and classification criteria have been proposed over time. However, all of these criteria have a main limitation, which is the difficulty to identify patients at an early stage of the disease. The Assessment of Spondyloarthritis International Society (ASAS) proposed the ASAS classification criteria that introduced two major changes: first, the classification of patients with SpA based on the predominant symptoms (axial or peripheral); second, the introduction of magnetic resonance imaging, which allows detection of sacroiliitis at the early stages of the disease. Nowadays, the ASAS criteria classify SpA in two groups: axial SpA, including classical AS and non-radiographic axial SpA, and peripheral SpA. The therapy for SpA has evolved dramatically over time. The introduction of biological therapy in recent years, which has continuously progressed, has improved the functional and clinical prognosis of SpA patients.
The Evolving Biosimilar Landscape: Approval of the First Etanercept Biosimilar in Europe, An Interview With Emilio Martín-Mola
Authors: Charles Caroline
Published: April 2023

On January 14th 2016, SB4 (Benepali®) received marketing authorisation application approval from the European Commission (EC). It is the first biosimilar to etanercept available in Europe as well as the first subcutaneous anti-tumour necrosis factor biosimilar. Benepali® was approved for the treatment of rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis (ankylosing spondylitis and non-radiographic spondyloarthritis), and plaque psoriasis.

SB4 adds to the available biologic armamentarium of biosimilars in rheumatology, which also includes two infliximab biosimilars; one under the brand names Remsima® and Inflectra®, and the other under the brand name Flixabi®. Unlike infliximab biosimilar, which is a chimeric monoclonal antibody, SB4 is a fusion protein.

We aimed to review the current European Medicines Agency (EMA) requirements for the approval of biosimilars and how these products can integrate into daily clinical practice in rheumatology.

To that effect, we recently discussed with Dr Emilio Martín-Mola about the European framework for approval of biosimilars and the controversies that may surround this new category of medicinal products. We discussed how the advent of biosimilars in rheumatology has the potential to truly be a game-changer for both physicians and patients.