bluuebunny/crossref_metadata_2025 huggingface dataset:
CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment
Authors: Han Yan , Wu Chunlei , Wang Jing , Liu Na
Published: May 2017

The major cause of death in osteosarcoma is the invasion and metastasis. Better understanding of the molecular mechanism of osteosarcoma invasion is essential in developing effective tumor-suppressive therapies. Interaction between chemokine receptors plays a crucial role in regulating osteosarcoma invasion. Here, we investigated the relationship between CXCR7 and CXCR4 in osteosarcoma invasion induced by bone marrow microenvironment. Human bone marrow mesenchymal stem cells were co-cultured with osteosarcoma cells to mimic actual bone marrow microenvironment. Osteosarcoma cell invasion and CXCL12/CXCR4 activation were observed within this co-culture model. Interestingly, in this co-culture model, osteosarcoma cell invasion was not inhibited by suppressing CXCR4 expression with neutralizing antibody or specific inhibitor AMD3100. Downstream signaling extracellular signal–regulated kinase and signal transducer and activator of transcription 3 were not significantly affected by CXCR4 inhibition. However, suppressing CXCR4 led to CXCR7 upregulation. Constitutive expression of CXCR7 could maintain osteosarcoma cell invasion when CXCR4 was suppressed. Simultaneously, inhibiting CXCR4 and CXCR7 compromised osteosarcoma invasion in co-culture system and suppressed extracellular signal–regulated kinase and signal transducer and activator of transcription 3 signals. Moreover, bone marrow microenvironment, not CXCL12 alone, is required for CXCR7 activation after CXCR4 suppression. Taken together, suppressing CXCR4 is not enough to impede osteosarcoma invasion in bone marrow microenvironment since CXCR7 is activated to sustain invasion. Therefore, inhibiting both CXCR4 and CXCR7 could be a promising strategy in controlling osteosarcoma invasion.
The prognostic value of p53 positive in colorectal cancer: A retrospective cohort study
Authors: Wang Peng , Liang Jianwei , Wang Zheng , Hou Huirong , Shi Lei , Zhou Zhixiang
Published: May 2017

This retrospective cohort study aimed to discuss the prognostic value of p53 positive in colorectal cancer. A total of 124 consecutive patients diagnosed with colorectal cancer were evaluated at the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College from 1 January 2009 to 31 December 2010. The expression of p53 in colorectal cancer was examined by immunohistochemistry. Based on the expression levels of p53, the 124 patients were divided into a p53 positive group and a p53 negative group. In this study, 72 patients were in the p53 positive group and 52 in the p53 negative group. The two groups were well balanced in gender, age, body mass index, American Society of Anesthesiologists scores, and number of lymph nodes harvested. p53 positive was associated with carcinoembryonic antigen ≥5 ng/mL ( p = 0.036), gross type ( p = 0.037), degree of tumor differentiation ( p = 0.026), pathological tumor stage ( p = 0.019), pathological node stage ( p = 0.004), pathological tumor–node–metastasis stage ( p = 0.017), nerve invasion ( p = 0.008), and vessel invasion ( p = 0.018). Tumor site, tumor size, and pathological pattern were not significantly different between these two groups. Disease-free survival and overall survival in the p53 positive group were significantly shorter than the p53 negative group ( p = 0.021 and 0.025, respectively). Colorectal cancer patients with p53 positive tended to be related to a higher degree of malignancy, advanced tumor–node–metastasis stage, and shorter disease-free survival and overall survival. p53 positive was independently an unfavorable prognostic marker for colorectal cancer patients.
A substantial peer workforce in a psychiatric service will improve patient outcomes: the case for
Authors: Dark Frances , Patton Murray , Newton Richard
Published: May 2017

Objectives:

This statement of opinion relates to an invited debate on the role of peer workers in psychiatric services during the Royal Australian and New Zealand College of Psychiatrists conference 2016. The views presented in this statement of opinion are those of the team for the affirmative.

Conclusions:

Peer workers are increasingly being employed within mental health services. Early adopters of this new workforce note advantages in terms of engagement of peers but also a bidirectional sharing of knowledge between clinicians and peer workers that has been mutually beneficial. Greater research and evaluation needs to occur to understand how best to incorporate peer workers into mental health care.
Finite element simulation of ferromagnetic shape memory alloys using a revised constitutive model
Authors: Jafarzadeh Siavash , Kadkhodaei Mahmoud
Published: May 2017

In this article, a previously developed constitutive model for ferromagnetic shape memory alloys is phenomenologically enhanced using experimental observations. A modified phase diagram along with a method for calibration of the required model parameters is further presented. The model is implemented into a user material subroutine to equip commercial finite element software ABAQUS with the capability of simulating magneto-mechanical behaviors of ferromagnetic shape memory alloys. A combined convergence scheme is employed to solve the implicit equations. The proposed model together with the presented numerical solution is shown to be able to study shape memory effect and pseudoelasticity at different constant magnetic fields. The simulated magnetic loading/unloading cycles at different constant stresses are found to be well-fitted to the experimental findings. As a practical application of the ferromagnetic shape memory alloy coupled magneto-mechanical response, a spring actuator (a bias spring serially connected to one ferromagnetic shape memory alloy element) is investigated, and the numerical predictions are shown to be in a good agreement with available experimental results. As a novel case, geometrically graded NiMnGa elements are also introduced and are simulated with the use of this approach.
Characterization of Free Phenytoin Concentrations in End-Stage Renal Disease Using the Winter-Tozer Equation
Authors: Soriano Vincent V. , Tesoro Eljim P. , Kane Sean P.
Published: May 2017

Background: The Winter-Tozer (WT) equation has been shown to reliably predict free phenytoin levels in healthy patients. In patients with end-stage renal disease (ESRD), phenytoin-albumin binding is altered and, thus, affects interpretation of total serum levels. Although an ESRD WT equation was historically proposed for this population, there is a lack of data evaluating its accuracy. Objective: The objective of this study was to determine the accuracy of the ESRD WT equation in predicting free serum phenytoin concentration in patients with ESRD on hemodialysis (HD). Methods: A retrospective analysis of adult patients with ESRD on HD and concurrent free and total phenytoin concentrations was conducted. Each patient’s true free phenytoin concentration was compared with a calculated value using the ESRD WT equation and a revised version of the ESRD WT equation. Results: A total of 21 patients were included for analysis. The ESRD WT equation produced a percentage error of 75% and a root mean square error of 1.76 µg/mL. Additionally, 67% of the samples had an error >50% when using the ESRD WT equation. A revised equation was found to have high predictive accuracy, with only 5% of the samples demonstrating >50% error. Conclusion: The ESRD WT equation was not accurate in predicting free phenytoin concentration in patients with ESRD on HD. A revised ESRD WT equation was found to be significantly more accurate. Given the small study sample, further studies are required to fully evaluate the clinical utility of the revised ESRD WT equation.
Frailty assessment instruments in heart failure: A systematic review
Authors: McDonagh Julee , Martin Lily , Ferguson Caleb , Jha Sunita R , Macdonald Peter S , Davidson Patricia M , Newton Phillip J
Published: May 2017

Background:

Frailty is an independent predictor of mortality across many conditions. Reported rates of frailty in heart failure range from 15% to 74%. There are several instruments available to assess frailty; however, to date there has been no consensus on the most appropriate instrument for use in individuals with heart failure.

Aims:

To identify how frailty is assessed in individuals with heart failure and to elucidate which domains of frailty are most frequently assessed.

Methods:

Key electronic databases were searched (MEDLINE, COCHRANE Central and CINAHL) to identify studies that assessed frailty in individuals with heart failure using a formal frailty instrument.

Results:

Twenty studies published in 24 articles were included, for which a total of seven unique frailty instruments were identified. The most commonly used instrument was the Frailty Phenotype ( n= 11), with the majority of studies using a modified version of the Frailty Phenotype ( n= 8). The second most commonly used instrument identified was the Comprehensive Geriatric Assessment ( n= 4).

Conclusion:

There is an increasing interest in the assessment of frailty, but, to date, there is no frailty instrument validated specifically in the heart failure population.
Reference-free detection of minute, non-visible, damage using full-field, high-resolution mode shapes output-only identified from digital videos of structures
Authors: Yang Yongchao , Dorn Charles , Mancini Tyler , Talken Zachary , Theiler James , Kenyon Garrett , Farrar Charles , Mascareñas David
Published: May 2017

Detecting damage in structures based on the change in their dynamics or modal parameters (modal frequencies and mode shapes) has been extensively studied for three decades. The success of such a global, passive, vibration-based method in field applications, however, has long been hindered by the bottleneck of low spatial resolution vibration sensor measurements. The primary reason is that damage typically initiates and develops in local regions that need to be captured and characterized by very high spatial resolution vibration measurements and modal parameters (mode shapes), which are extremely difficult to obtain using traditional vibration measurement techniques. For example, accelerometers and strain-gauge sensors are typically placed at a limited number of discrete locations, providing low spatial resolution vibration measurements. Laser vibrometers provide high-resolution measurements, but are expensive and make sequential measurements that are time- and labor-consuming. Recently, digital video cameras—which are relatively low cost, agile, and able to provide high spatial resolution, simultaneous, pixel measurements—have emerged as a promising tool to achieve full-field, high spatial resolution vibration measurements. Combined with advanced vision processing and unsupervised machine algorithms, a new method has recently been developed to blindly and efficiently extract the full-field, high-resolution, dynamic parameters from the video measurements of an operating, output-only structure. This work studies the feasibility of performing damage detection using the full-field, very high spatial resolution mode shape (of the fundamental mode) blindly extracted from the video of the operating (output-only) structure without any knowledge of reference (healthy) structural information. A spatial fractal dimension analysis is applied on the full-field mode shape of the damaged structure to detect damage-induced irregularity. Additionally, the equivalence between the fractal dimension and the squared curvature (modal strain energy) of the mode shape curve, when of high spatial resolution, is mathematically derived. Laboratory experiments are conducted on bench-scale structures, including a building structure and a cantilever beam, to validate the approach. The results illustrate that using the full-field, very high-resolution mode shape enables detection of minute, non-visible, damage in a global, completely passive sensing manner, which was previously not possible to achieve.
End-Stage Renal Disease Negatively Affects Physical Quality of Life in Patients With Diabetic Foot Complications
Authors: Raspovic Katherine M. , Ahn Junho , La Fontaine Javier , Lavery Larry A. , Wukich Dane K.
Published: May 2017

The aim of this study was to evaluate the impact of end-stage renal disease (ESRD) on health-related quality of life (QOL) in patients with diabetic foot disease. We compared a group of 30 diabetic patients with ESRD requiring dialysis to a group of 60 diabetic patients without ESRD. Both groups consisted of patients with active diabetic foot disease (ulcer, Charcot, infection) and were matched with regard to age and gender. Self-reported QOL was assessed using the Short Form-36 (SF-36) physical and mental component summary (PCS and MCS) scores and the region-specific Foot and Ankle Ability Measure (FAAM). Diabetic foot patients with ESRD requiring dialysis were found to have significantly higher creatinine levels, lower hemoglobin levels, lower albumin levels, higher rates of peripheral arterial disease, and lower rates of Charcot neuroarthropathy than patients without ESRD. The median PCS was significantly lower in the ESRD group; however, no significant difference was found when comparing the median MCS and FAAM. Patients who ultimately died had a tendency to report lower PCS scores at baseline compared with those patients who did not die ( P = .07). Patients who ultimately required major amputation also reported lower PCS scores at baseline. ESRD negatively affects physical QOL to a greater degree than mental QOL in patients with diabetic foot disease. The SF-36 may not be sensitive enough to capture impaired mental QOL because both groups had relatively high MCS scores. Low physical QOL may be associated with mortality and the eventual need for major amputation.
Roger Caillois and Marxism: A Game Studies Perspective
Authors: Kristensen Lars , Wilhelmsson Ulf
Published: May 2017

The authors look at Caillois’ reflections on the dichotomy between work and leisure in relation to Marxism, whose dialectics are shown to influence the milieu under which Caillois developed his ideas. The contribution interrogates this labor/play dialectic while looking at recent literature on games being produced within the current capitalist and neoliberal system, focusing on phenomena like “playbour” and on key elements discussed in these theories, from the affordances and limitations of technology to the immaterial technological tools used by gamers and game makers. The article argues that looking at Caillois in relation to Marxism would provide an interesting critical perspective, one that has been underexplored by current approaches. The authors note that contemporary concerns on capitalism and games are far from being at odds with Caillois’ distinction between labur and play and suggest that the influence of Marxism on Caillois’ writings would provide an interesting terrain of further discussion.
The Effects of the Bali Yoga Program for Breast Cancer Patients on Chemotherapy-Induced Nausea and Vomiting: Results of a Partially Randomized and Blinded Controlled Trial
Authors: Anestin Annélie S. , Dupuis Gilles , Lanctôt Dominique , Bali Madan
Published: May 2017

Complementary and alternative medicine has been shown to be beneficial in reducing chemotherapy-induced nausea and vomiting. However, conclusive results are lacking in order to confirm its usefulness. The purpose of this study was to determine whether a standardized yoga intervention could reduce these adverse symptoms. This was a partially randomized and blinded controlled trial comparing a standardized yoga intervention with standard care. Eligible patients were adults diagnosed with stages I to III breast cancer receiving chemotherapy. Patients randomized to the experimental group participated in an 8-week yoga program. There was no significant difference between the experimental and control groups on chemotherapy-induced nausea and vomiting after 8 weeks. Results suggest the yoga program is not beneficial in managing these adverse symptoms. However, considering preliminary evidence suggesting yoga’s beneficial impact in cancer symptom management, methodological limitations should be explored and additional studies should be conducted.
The Cumulative Force of Analogies
Authors: Botting David
Published: May 2017

In this paper I will argue that most objections to deductive analyses of a priori analogies are incorrect, often involve basic misinterpretations of what the deductive reconstruction of those arguments are saying, and sometimes also betray a confusion about what part of the reasoning corresponds to the analogical inference. In particular, I will be focusing on a raft of objections made by Juthe in [2015] and subject his alternative views to criticism.I will then argue that Juthe does implicitly have a good argument against deductivism: adding further analogues seems to have a cumulative force that they would not have on a deductivist analysis. This is so not only in ordinary analogical arguments but, perhaps surprisingly, with a priori analogical arguments. I will then argue that this does not favor a sui generis view of the analogical argument over inductivist views, and attempt to show that a confirmation-theoretic approach to analogical inference makes the best sense of our intuitions about the strength of analogical arguments.
Spatial Heterogeneity, Broadband, and New Firm Formation
Authors: Parajuli Jitendra , Haynes Kingsley
Published: May 2017

Purpose: This paper examines the spatial heterogeneity associated with broadband Internet and new firm formation in a number of U.S. states.Methodology/Approach: Both ordinary least-squares regression and Geographically Weighted Regression are used for the estimation purpose.Findings: The global coefficient estimates of ordinary least-squares regression account for the marginal change in a phenomenon, but such a global measure cannot reveal the locally-varying dynamics. Using Geographically Weighted Regression, it was found that at the aggregate and economic sector levels, the association between single-unit firm births and the provision of broadband Internet varies across counties in Florida and Ohio.Originality/Value of paper: There are numerous studies on broadband Internet in the U.S., but this is the first that explicitly examines broadband provision and new firm formation by taking into account spatial heterogeneity across countries.
LEITURA, EXPERIMENTAÇÃO ARTÍSTICA E PRODUÇÃO TEXTUAL NAS SÉRIES INICIAIS DO ENSINO FUNDAMENTAL
Authors: Lubian Maria Emília
Published: May 2017

A produção textual baseada na leitura e expressão artística faz com queos alunos demonstrem interesse em divulgar suas idéias, isto porque envolveuma atividade prazerosa, há interlocutores reais para os textos produzidos etambém o auxilio dos colegas para que os textos se tornem melhores na provocaçãode sentidos dentro do gênero escolhido. Dessa forma, relacionamos estaabordagem com a enunciação, visto que esta visão contempla o “ter o quedizer”, “a quem dizer” e a descoberta de diferentes maneiras de “como dizer” na produção textual. As leituras de gêneros textuais narrativos e poéticos, observando as suas características de forma e conteúdo aplicadas na produção dos textos pelos grupos de alunos, bem como a divulgação destes em “histórias na sacola”, em sarais, hora do conto, dramatização envolvendo as produções dos alunos e textos dos autores trabalhados, são apresentados neste trabalho em escola da rede municipal de ensino de Não-Me-Toque com crianças de terceira e quarta séries. Dessa forma, o nosso trabalho objetiva relacionar práticas de leitura e escrita, envolvendo a expressão artística desenvolvidas com alunos de séries iniciais do ensino fundamental.
O CONSÓRCIO DA CIÊNCIA E DA ARTE ENQUANTO PROJETO ESTÉTICO NORTEADOR D’OS SERTÕES, DE EUCLIDES DA CUNHA
Authors: Dias Léa Costa Santana
Published: May 2017

Neste artigo, parte-se da própria concepção euclidiana do consórcio entreciência e arte e se constrói um diálogo entre ambas, entendendo-as comopartes indissociáveis de um mesmo discurso, que se interpenetram durante todaa narrativa, dando a Euclides a oportunidade de se constituir como aquilo queele acreditava ser o escritor do futuro.
NARRATIVA CONTEMPORÂNEA: A LINGUAGEM CINEMATOGRÁFICA EM ESTORVO
Authors: Reis Mírian Sumica Carneiro , Novaes Claudio Cledson
Published: May 2017

O artigo analisa as possibilidades de intersecção das linguagens na representação do narrador em sua trajetória paranoica pelo tempo, pelos lu-gares e pela própria percepção de si e dos outros no romance Estorvo, de Chico Buarque, e na adaptação cinematográfica homônima, feita por Ruy Guerra. Privilegiando o filme, para melhor compreensão dos recursos explo-rados na obra, foi considerada também a perspectiva do próprio cineasta, a-través de entrevistas em que ele esclarece os motivos que o conduziram à adaptação do romance e os recursos eleitos para a montagem de modo a “traduzir” em filme as características prenunciadas no romance.
DADOS SOBRE AS RELAÇÕES ENTRE CINEMA E LITERATURA NO CINEMA NOVO BRASILEIRO
Authors: Amar Víctor
Published: May 2017

Neste artigo a ideia principal é estabelecer um esquema comparati-vo abordando as relações entre o cinema e a literatura, com destaque para o cinema novo brasileiro. O mote principal do trabalho leva-nos a relacionar o romance e o cinema, mas nossa intenção é estabelecer um cômputo de rela-ções entre o cinema e a literatura de cordel, o teatro e a música/poesia. Quer dizer, nosso interesse é abordar dados que tornam possíveis as relações entre a literatura e o cinema novo brasileiro. Um documento escrito com ri-gor busca sinais documentais da época em consonância com outros mais atuais.
UM PASSEIO PANORÂMICO PELA PRODUÇÃO LITERÁRIA INFANTO-JUVENIL MOÇAMICANA: AUTORES E OBRAS
Authors: Oliveira Maria Anória de Jesus
Published: May 2017

O presente texto visa a apresentação panorâmica da produção literária infanto-juvenil moçambicana contemporânea. Para tanto, reali-zamos a pesquisa bibliográfica em Maputo, entre o período de maio a outu-bro de 2009. Identificamos temas diversificados abrangendo-se desde o pa-triotismo às problemáticas sociais, a exemplo da guerra, da orfandade, da pobreza e do predomínio das narrativas tradicionais. Os personagens, de modo geral, são apresentados com fenótipos negros nas ilustrações, muito embora sem referencia a tais traços na linguagem verbal. Esperamos, através desse estudo, colaborar para visibilizar tais produções no mercado livresco, haja vista a carência de pesquisas acerca delas tanto em Moçambique quanto no Brasil.
A LITERATURA-TERREIRO NA CENA HIP HOP AFROBAIANA
Authors: Santos José Henrique De Freitas
Published: May 2017

Este artigo propõe o conceito de literatura-terreiro, através da análise de produções artísticas do movimento hip hop que se vinculam aos valores civilizatórios afro-brasileiros, bem como às noções de encruzilhada e ancestralidade presentes nas religiões afro-brasileiras. Com este objetivo, utilizaremos as considerações teóricas de Eduardo Oliveira sobre a filosofia da ancestralidade; Gunther Kress e Van Leween sobre multimodalidade; Amarino Queiroz e Paul Zumthor, sobre oralidade e performance.
O ENSINO PROFISSIONAL FEMININO NO BRASIL: UMA ANÁLISE DA ESCOLA PROFISSIONAL FEMININA NILO PEÇANHA (CAMPOS, RIO DE JANEIRO, 1922-1930)
Authors: Reis Fabiana De Arruda Resende , Martinez Silvia Alicia
Published: May 2017

Com o processo industrial e de modernização do Brasil, surgiu o en- sino profissional, inclusive o feminino, que muitas vezes preparava as mulhe- res para serem melhores donas do lar e para ajudarem no orçamento famili- ar, qualificando-as para trabalharem fora de casa como professoras de arte ou até mesmo confeccionarem produtos para serem vendidos. Neste contex- to visamos apresentar os primeiros resultados relativos ao estudo explorató- rio do ensino profissional feminino no estado do Rio de Janeiro, tendo como referência e objeto de estudo a Escola Profissional Feminina Nilo Peçanha, fundada em 1922 na cidade de Campos. Para tal, optamos pelo recorte tem- poral de 1922 a 1930, correspondente ao período entre o ano de criação da escola até o final da gestão da primeira diretora da instituição.
DINÂMICA CULTURAL E CONSTRUÇÃO IDENTITÁRIA: REFLEXÕES EM TORNO DE UMA ETNOGRAFIA CONTEMPORÂNEA
Authors: Messeder Marcos Luciano Lopes
Published: May 2017

Este texto tem como proposta produzir uma reflexão meta- etnográfica no contexto das relações interétnicas no Nordeste do Brasil, bus- cando descrever os caminhos teóricos e metodológicos que traçamos em nossa pesquisa sobre a relação entre o consumo de álcool e a etnicidade en- tre os Tremembé do Ceará. Em um primeiro momento, procuramos descre- ver o campo empírico da pesquisa, associando-o ao contexto das relações in- terétnicas que organizam a realidade dos índios no Nordeste. Em seguida, discutimos as tensões colocadas à elaboração do quadro teórico e metodoló- gico a partir do qual construímos o trabalho de investigação. Ao final, apre- sentamos algumas reflexões sobre o conjunto dos dados recolhidos e suas implicações para a articulação entre política e elaboração cultural no âmbito dos estudos sobre etnicidade entre os índios no Nordeste brasileiro.
OS CAPSAD, AS COMUNIDADES TERAPÊUTICAS E O “USUÁRIO DE DROGAS”: POLÊMICAS E PARADOXOS
Authors: César Elisson Alexandre Ferreira , Rodrigues Luzania Barreto
Published: May 2017

O trabalho ora proposto reflete sobre dados empíricos provenientes de três campos de investigação: 1) o Centro de Atenção Psicossocial Álcool e outras Drogas (CAPSad); 2) uma comunidade terapêutica de cunho evangélico; e 3) o Coletivo Ciranda de Rua de Redução de Danos, dispositivos de atenção e cuidado dispensados a usuários de substâncias psicoativas (SPA). Utilizando-se de algumas técnicas importantes ao trabalho etnográfico, como  a observação participante, as conversas informais e as entrevistas gravadas, pôde-se aceder a questões que explicitam controvérsias quanto à prática da Política Nacional direcionada a este público específico, bem como desvela debates polêmicos sobre a incidência de padrões morais e normas de condu- ta no tratamento aí implicado, além de ser privilegiado o uso de fármacos em detrimento de outras medidas terapêuticas. Diante disso, atentamos para a necessidade premente de políticas eficazes de assistência social em consonância com uma assistência de saúde que possa contemplar as múltiplas dimensões que abarca o fenômeno estudado, seja em espaços institucionalizados ou em territórios de consumo.
O INSÓLITO NOS CORDÉIS DE FRANKLIN MAXADO
Authors: Oliveira Calila Das Mercês , Galvão Raquel Machado , Seidel Roberto Henrique
Published: May 2017

O insólito nos cordéis de Franklin Maxadopropõe uma análise acerca de quatro livretos de cordel do escritor e poeta baiano Franklin Maxado, dis-cutindo quadros do elemento insólito recorrentes nos cordéis, aqui entendi-dos por fatos extraordinários, não habituais à realidade. Valorizada por al-guns estudiosos como a raiz da cultura luso-brasileira, ou da cultura popular, a literatura de cordel herda características da literatura oral dos antigos tro-vadores. Os livretos artesanais, por vezes acompanhados de xilogravuras, fo-ram distribuídos, inicialmente, em feiras livres, e tiveram em Feira de Santa-na, cidade do agreste da Bahia onde Franklin nasceu, um importante ponto de distribuição. É recorrente na literatura de cordel a utilização de narrações ritmadas e originais que abarcam o fantástico e o maravilhoso. Isto pode ser verificado neste estudo. As teorias presentes no artigo se baseiam em Tzve-tan Torodov, Italo Calvino, Câmara Cascudo, Remo Ceserani, IrlemarChiampi, entre outros.
OS INQUIETANTES E INSÓLITOS ANJOS LATINO-AMERICANOS
Authors: Gama-Khalil Marisa Martins
Published: May 2017

O artigo tem como proposta a discussão da noção de real maravilhoso, uma das vertentes da literatura fantástica, por intermédio da análise de dois contos de autores latino-americanos: “Um senhor muito velho com umas asas enormes”, de Gabriel García Márquez, e “Um moço muito bran- co”, de João Guimarães Rosa.
O INSÓLITO NA OBRA DE JOÃO GILBERTO NOLL OU O APRENDIZADO DA TRANSGRESSÃO
Authors: Carreira Shirley De Souza Gomes Carreira
Published: May 2017

Na literatura brasileira contemporânea, há autores que incorporam aos seus textos acontecimentos insólitos que devem ser observados à luz das teorias relativas ao insólito ficcional. Este trabalho tem por objetivo analisar  o insólito na obra de João Gilberto Noll, de modo a comprovar que a sua presença nos textos do autor constitui uma via para transgressões que operam não apenas no âmbito da diegese, mas também na arquitetura do texto.
De manuscritos históricos a corpora anotados: do Documento Digital Texto (DDT) ao corpus anotado
Authors: Santos Jorge Viana , Namiuti Cristiane
Published: May 2017

Este artigo apresenta a etapa de Compilação do método LAPELINC (Laboratório de Pesquisa em Linguística de Corpus), o qual envolve a integração de três objetos fundamentais na construção de corpora digitais: Documento Físico (DF); Documento Digital Imagem (DDI); Documento Digital Texto (DDT). Tal etapa é responsável por alterar a codificação do digital de visual-imagética para verbal-textual, passagem que envolve transcrição. Nos limites deste trabalho, consideramos as limitações e as possibilidades dos suportes materiais da escrita com destaque para as complexidades do suporte digital.
Interfaces entre Crítica Textual e Informática na edição de textos teatrais censurados
Authors: De Almeida Isabela Santos
Published: May 2017

No presente artigo, discorremos acerca das relações entre a Crítica Textual e a Informática, situando-as no campo dos estudos em Humanidades Digitais. A fim de refletir sobre tal questão, tomamos a prática de edição dos textos teatrais censurados de Jurema Penna para verificar algumas atualizações conceituais e metodológicas decorrentes desse contato disciplinar.
NARRADOR SILENCIOSO? UMA LEITURA DE PEPETELA SOB A ÓPTICA DO DISCURSO DE MICHEL FOUCAULT
Authors: Neto Sebastião Marques
Published: May 2017

objetivo deste artigo é discutir o silenciamento e o silêncio da voz narrativa em A gloriosa família, do escritor angolano Pepetela – pseudônimo de Arthur Carlos Maurício Pestana dos Santos – (1999). Inspirado em Fou-cault, proponho-me a tratar alguns enunciados da obra, a partir do seu pen-samento sobre a noção de discurso e poder, buscando a multiplicidade de acontecimentos que operam nos jogos entre o real e o ficcional; entre o fato histórico e a suas versões imersas nas práticas sociais. A idéia é articular o foco narrativo em seu duplo movimento: ora silenciado, ora em afasia, den-tro de um contexto cujas relações de poder buscam ecos na escrita do filóso-fo francês.
A REPRESENTAÇÃO DA MODERNIDADE NA POESIA DE CHARLES BAUDELAIRE
Authors: Kirchof Edgar Roberto
Published: May 2017

O presente artigo aborda a poesia de Charles Baudelaire, a partir da maneira como o poeta representa o tema da Modernidade, em As flores do mal. Baudelaire retrata esse tema principalmente através da imagem da cida-de, bem como de objetos urbanos. O artigo divide-se em duas partes. Inici-almente, discute-se a maneira como a crítica literária tem compreendido a vinculação da poesia baudelairiana com o tema da Modernidade. Nessa se-ção, são apresentados os principais conceitos a partir dos quais é possível compreender como Baudelaire concebia as transformações sociais e históri-cas de sua época, especialmente o spleen, o erotismo e o satanismo. Na se-gunda parte, esses problemas passam a ser abordados a partir dos Quadros parisienses, em As flores do mal, analisando-se, em profundidade, o poema Paysage.
NO JARDIM DO MAL: BAUDELAIRE NO BRASIL
Authors: Ferreira Raul Azevedo de Andrade
Published: May 2017

O volume de poesias intitulado Les fleurs du mal, publicado em 1857, por Charles Baudelaire, firmou-se como marco decisivo na trajetória da lite-ratura moderna. Tal importância, contudo, apenas pôde ser atingida por sua obra conter em si uma alta carga de possibilidades semânticas, propriedade identificada por Paul Valéry como durée. Este ensaio busca discorrer sobre como a durée de Les fleurs du mal foi processada nas primeiras recepções da obra de Baudelaire, no Brasil, analisando como ela sofreu uma série de mo-dulações em função da conjuntura política do país.
A POIESIS DE “TRANSVERSÃO DA MEMÓRIA” E A SUPERAÇÃO DAS APORIAS TROPICAIS: UMA LEITURA BERGSONIANA DO CATATAU, DE LEMINSKI
Authors: De Souza Carlos Cézar Mascarenhas
Published: May 2017

Trata-se de um estudo sobre a questão da memória, a partir do diá-logo entre o texto literário Catatau, de Paulo Leminski, e o pensamento de Henri Bergson. Partindo do pressuposto de que o texto de Leminski pro-blematiza e traz à tona um dos impasses ou aporias mais marcantes da cultu-ra brasileira, que se expressa nos dilemas das discusssões entre as dicotomias do nacional versus estrangeiro, original versus cópia e congêneres, sugerimos, através deste trabalho, a operação da Poiesis de Transversão da Memória como uma modalidade de leitura essencialmente voltado à superação das di-cotomias que sustentam os dilemas nas aporias da cultura.
A REPRESENTAÇÃO SÓCIO-CULTURAL DO COTIDIANO RURAL NA PRODUÇÃO ARTÍSTICA DO GRUPO DA QUIXABEIRA
Authors: Dos Santos Ricardo Ferreira
Published: May 2017

Pensar as linguagens musicais da cultura regional torna-se oportuno na medida em que representam a nossa mais genuína canção popular. De uma forma simples e profundamente poética a música regional se configura como uma referência para revitalização da arte contemporânea. E o Grupo da Quixabeira constitui-se numa das mais importantes manifestações musicais do sertão e parte do recôncavo baiano, agregando várias comunidades de Feira de Santana e região, que são formadas por trabalhadores rurais que fazem do labor cotidiano uma expressão cultural rica em divertimento e poesia. Essas comunidades têm a música como uma forma de manter vivas as tradições folclóricas do povo sertanejo, evidenciando o modo de vida do nordeste interiorano. Nesse sentido, o trabalho discute a produção artística do Grupo da Quixabeira como uma forma de representação cultural na contemporaneidade.
ESTRUTURA PÓS-COLONIAL DE “QUARUP”, DE CALLADO
Authors: De Souza Licia Soares
Published: May 2017

Este trabalho analisa Quarup (1967) de Antonio Callado. Consideradoum romance de êxodo reverso, segundo o modelo narrativo explorado por Euclides da Cunha, cujos viajantes partem da metrópole para averiguar os modos de existência do Brasil profundo, nos sertões ou nas reservas indígenas, Quarup é classificado como um romance de tese. Correlacionando várias correntes de pensamento, em ondas dialéticas de tese e antítese (getulismo, comunismo, indigenismo, folclorismo, sertanismo, europeísmo, cubanismo, etc.), Callado desenvolve uma narrativa apta a mostrar as tendências ideológicas que guiavam as comunidades nos conturbados anos do início da ditadura militar. Pretendemos mostrar que esse tipo de romance de tese, cujo entrelaçamento de correntes de pensamento diferenciados surge espelhando os impasses causados pela adoção de ideologias importadas, com caracteres colonialistas, muitas vezes, constitui o embrião do romance pós-colonial que politiza o estético no Brasil.
A MEDIAÇÃO LÍQUIDA DA NARRATIVA
Authors: Ferreira Lucelena
Published: May 2017

O texto apresenta uma análise do livro As cidades invisíveis, de Italo Calvino, a partir do conceito de modernidade líquida, de Zygmunt Bauman, enfocando a questão da mediação da narrativa.
Nudging: ‘Soft’ mind-bending through politics and media – an issue for civil rights activists?
Authors: Piasecki Stefan
Published: May 2017

‘Nudging’, a form of motivational help to make people change their behaviour, habits or attitudes, is becoming more and more popular. While initially mainly used in sales, marketing and advertising, its principles and methods, also referred to as ‘behavioural design’ or ‘behavioural economics’, have been refined and expanded over the past 30 years, now making it also suitable for politics and public services. Nudging is and can be used to help people change their behaviour regarding energy consumption, health precautions etc. On the other hand, political nudging performed by authorities may, if carelessly performed, seriously damage the public trust. First the term and meaning of ‘nudging’ will be introduced. It has a much longer and richer history than recent mention in the German public sphere indicates. Then examples of current uses will be given and possible political and cultural implications will be discussed. This article refers to international sources and discourses but concentrates on shedding light on nudging in Germany.
Undocumented identity storytelling: (Re)framing public relations
Authors: Ortiz Juarez-Paz Anna V.
Published: May 2017

The Undocumented Student Movement (USM) consists of members of a historically misrepresented and excluded population in the United States. Taking matters into their own hands, they have gained a voice in mainstream media and society today. In this article, I seek to document the communicative acts of resistance employed by undocumented students in the United States. Specifically, I argue that the communicative acts currently employed by the USM answer the call for a more critical and engaged theory of public relations. The USM offers alternative ways to communicate with publics through the use of undocumented identity storytelling. By employing the culture-centred approach to communication, I examine undocumented identity storytelling through participant observation and in-depth interviews with members of the movement.
Combining different treatment philosophies and techniques to reach the desired treatment goal using butterfly system-customizing orthodontic treatment
Authors: Lekhadia Dhaval
Published: May 2017

This case report describes the orthodontic treatment of an 18-year-old male patient who presented with Straight profile; tongue thrust habit, proclined upper incisors, generalised spacing in upper and lower arches, Katz's class II premolar relation unilaterally, class II canine relation unilaterally with increased overjet and overbite. A butterfly system was used in the treatment combined with frictionless biomechanics in the initial stage of treatment followed by continuous arch mechanics in the later part of treatment. A tongued crib was used to stop the tongue thrust habit along with one elastic swallow exercise. Micro-implant anchorage was used unilaterally in the upper arch for retraction of the entire segment and correction of the unilateral class II canine and premolar relationship. To avoid a dished in profile, a non-extraction treatment was executed. Final corrections of distally tipped canines were achieved using conventional Begg’s  uprighting auxiliaries in the vertical slots of butterfly system in the finishing stage. The case was finished using bite settling elastics. Total treatment time was 1 year 2 months. Aesthetic and functional goals were achieved satisfactorily with proper selection of biomechanics.
Medical students utilization of e-learning re-sources; is it an informal curriculum?
Authors: Yaseen Maria , Bano Misbah , Jawaid Masood
Published: May 2017

Background: E-learning refers to the use of Internet technologies to deliver a broad range of solutions that enhance knowledge and per-formance of learners. This mode of learning can be used by institutions to improve the efficiency and effectiveness of educational inter-ventions in the face of the social, scientific, and pedagogical challenges. Worldwide, it has gained popularity in the past few decades; however, its use is highly variable among the medical schools of Pakistan. Currently, a very few number of institutions have adopted it officially in their curriculum. Despite this, many students use different E Learning resources to enhance their learning.Objective: To find out about the online resources utilized by the medical students in addition to their traditional medical curriculum to enhance their learning.Method: In this cross-sectional study, 300 participants from Dow Medical College and Jinnah Sindh Medical Universities were included after taking informed consent. A self-administered questionnaire which consists of demographic information, years of study and online resources with their usage details by the students for different subjects of basic and clinical sciences were documented.Results: Almost all the students reported to use some form of eLearning to enhance their medical understanding. The most frequently used electronic resources were Google images (61.7%) and Wikipedia (50.3%). Mostly, the students used YouTube (25.7%) for animations; Kaplan (27%) and Dr. Najeeb (15.6%) for video lectures. However, Audio lecture by Goljan (17.7%) was the only resource for podcast learning. Among discussion forums, Facebook groups (16.3%) were most popular and among static websites, Medscape (4.3%), PubMed (2.5%), WebMD (1.3%) were the most commonly used ones.Conclusion: All of the medical students used some form of eLearning in medical education in addition to their formal curriculum. This way of learning should be further implemented in the form of formal curriculum as e-learning modules for basic and clinical sciences to make learning easier, engaging and innovative for the 21st century learners.
Adversarial versus Inquisitorial Systems: Error and Valuation
Authors: Rajagopalan Shruti
Published: May 2017

This paper discusses valuation within the judicial processes by comparing the adversarial and inquisitorial systems of litigation. It evaluates adversarial and inquisitorial litigation on the legal systems’ ability to aid processes that lead to discovery of knowledge. It argues that much of the information required for accurate valuation must be discovered. While the adversarial method of litigation is essentially a competitive model of evidence production; the inquisitorial system comprises only the expert/principle searcher, and lacks a competitive discovery process. Therefore, as a system, adversarial litigation may be more conducive for error minimization in enforcing rules than inquisitorial litigation. On the question of business valuation of firms under Chapter 11, both the adversarial and inquisitorial systems are problematic, given that market competition leading to discovery of prices and valuation is impossible within the judicial system of valuation.
Crystal structure of 3-(2-amino-1,3-selenazol-4-yl)-2H-chromen-2-one – dimethylformamide (1/1), C15H15N3O3Se
Authors: Alias Nurul Zawani , Ahmad Wan Yaacob Wan , Hassan Nurul Izzaty , Yamin Bohari M. , Ngatiman Mohammad Fadzlee
Published: May 2017

C15H15N3O3Se, triclinic, P1̅ (no. 2), a = 9.5686(7) Å, b = 12.3795(9) Å, c = 14.7854(11) Å, α = 93.844(2)°, β = 106.344(2)°, γ = 110.816(2)°, V = 1543.4(2) Å3, Z = 4, R
gt(F) = 0.0489, wR
ref(F
2) = 0.1066, T = 300 K.
Answering the Call
Authors: Callier Durell M. , Hill Dominique C. , Waters Hill L.
Published: May 2017

The organizers of the Autoethnography Special Interest Group for the 12th International Congress of Qualitative Inquiry brought together various autoethnographers to meditate on the theme of “manifesting” autoethnography. Taking up the challenge, the authors use reflexive narrative, poetry, music, and movement to offer one manifestation of autoethnography in the future. We, Hill L. Waters, write into the future, auto\ethnography as a Black, queer, collective, and spiritual praxis and politic. This future into which we are writing is borne of necessity to enhance the life chances and life possibilities of Black queer people.
Autoethnography
Authors: Poulos Christopher N.
Published: May 2017

Asked to write a manifesto for autoethnography, I find myself writing, instead, a manife story for auteothnography—a cry for scholars to engage the vibrating force of story-craft in service of our life-enhancing, knowledge-constructing, world-building praxis of the autoethnographic craft. I write to expose. I write to shine light. I write to open up the world to a new way of seeing, feeling, thinking, reflecting, smelling. I write it into a story of a life, a story of a human working like hell to navigate this choppy, murky, oddly human water we've all been shoved into. I write to build bridges, to probe and make meaning, to start a dialogue, to bring memory to light, to write relationships into being.
Autoethnography Manifesto
Authors: Diversi Marcelo , Moreira Claudio
Published: May 2017

We write about betweener autoethnographies in this manifesto. We see autoethnography as a way of knowing that has the potential to examine social justice, systems of oppression, and neocolonialism from our encounters with experiences lived in-between identities and worlds. We see life lived in between fixed identities and social categories as a common human experience, and as such, as places where we can expand the circle of Us while also decreasing notions of Them and Other.
Autoethnography as Hauntings
Authors: Purnell David
Published: May 2017

The purpose of this manifesto is for it to become a part of your hauntings. For it is in our interactions with the writings of those who have come before us that we become inextricable accomplices in the joys and travesties of learning and knowing. Our engagement with the writings of Dwight Conquergood, Bud Goodall, Nick Trujillo, and others unite our voices with theirs to create collaborations resulting in change. In that moment when those ghostly apparitions of our autoethnographic encounters rise and make their selves known, we will then be able to embrace our hauntings, face them, use them.
30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Evolution of the mineralocorticoid receptor: sequence, structure and function
Authors: Baker Michael E , Katsu Yoshinao
Published: May 2017

The mineralocorticoid receptor (MR) is descended from a corticoid receptor (CR), which has descendants in lamprey and hagfish, cyclostomes (jawless fish), a taxon that evolved at the base of the vertebrate line. A distinct MR and GR first appear in cartilaginous fishes (Chondrichthyes), such as sharks, skates, rays and chimeras. Skate MR has a strong response to corticosteroids that are mineralocorticoids and glucocorticoids in humans. The half-maximal responses (EC50s) for skate MR for the mineralocorticoids aldosterone and 11-deoxycorticosterone are 0.07 nM and 0.03 nM, respectively. EC50s for the glucocorticoids cortisol and corticosterone are 1 nM and 0.09 nM, respectively. The physiological mineralocorticoid in ray-finned fish, which do not synthesize aldosterone, is not fully understood because several 3-ketosteroids, including cortisol, 11-deoxycortisol, corticosterone, 11-deoxycorticosterone and progesterone are transcriptional activators of fish MR. Further divergence of the MR and GR in terrestrial vertebrates, which synthesize aldosterone, led to emergence of aldosterone as a selective ligand for the MR. Here, we combine sequence analysis of the CR and vertebrate MRs and GRs, analysis of crystal structures of human MR and GR and data on transcriptional activation by 3-ketosteroids of wild-type and mutant MRs and GRs to investigate the evolution of selectivity for 3-ketosteroids by the MR in terrestrial vertebrates and ray-finned fish, as well as the basis for binding of some glucocorticoids by human MR and other vertebrate MRs.