bluuebunny/crossref_metadata_2025 huggingface dataset:
The modified Lapidus fusion: a systematic review of biomechanical studies
Authors: Riegger Martin , Habib Nermine , Testa Enrique Adrian , Müller Jochen , Guidi Marco , Candrian Christian
Published: April 2023

Purpose

The biomechanical characteristics of different techniques to perform the modified Lapidus procedure are controversial, discussing the issue of stability, rigidity, and compression forces from a biomechanical point of view. The aim of this systematic review was to investigate the available options to identify whether there is a procedure providing superior biomechanical results.

Methods

A comprehensive literature search was performed by screening PubMed, Embase, and Cochrane databases until September 2021. There was a wide heterogeneity of the available data in the different studies. Load to failure, stiffness, and compression forces were summarized and evaluated.

Results

Seventeen biomechanical studies were retrieved – ten cadaveric and seven polyurethane foam (artificial bone) studies. Fixation methods ranged from the classic crossed screw approach (n = 5) to plates (dorsomedial and plantar) with or without compression screws (n = 11). Newer implants such as intramedullary stabilization screws (n = 1) and memory alloy staples (n = 2) were investigated.

Conclusion

The two crossed screws construct is still a biomechanical option; however, according to this systematic review, there is strong evidence that a plate–screw construct provides superior stability especially in combination with a compression screw. There is also evidence about plate position and low evidence about compression screw position. Plantar plates seem to be advantageous from a biomechanical point of view, whereas compression screws could be better when positioned outside the plate. Overall, this review suggests the biomechanical advantages of using a combination of locking plates with a compression screw.
Wyniki odległe korekcji warg sromowych mniejszych przy użyciu techniki radiofrekwencji – badanie pilotażowe
Authors: Kupny-Bujoczek Dominika , Paul Marek , Warchoł Krzysztof , Gabriel Iwona
Published: April 2023

Wstęp Labioplastyka, czyli korekcja warg sromowych mniejszych, jest zabiegiem wykonywanym w przypadku zaburzeń anatomicznych warg sromowych mniejszych. Cel W niniejszym badaniu ocenie podlegał wpływ nieprawidłowości w budowie sromu na psychikę i samoakceptację przed i po zabiegu. Następnie analizowano ból podczas wykonywania codziennych czynności i dyskomfort w czasie kontaktów seksualnych występujący przed i po zabiegu. Materiał i metody Do badania włączono pacjentki operowane w latach 2013–2017 przez jednego chirurga-ginekologa (IG). Kryterium włączenia stanowiły: wykonanie u pacjentki izolowanego zabiegu korekcji warg sromowych mniejszych metodą radio frekwencji. Kryterium wyłączenia stanowiły pacjentki, u których wykonano zabiegi łączone, np. waginoplastyka i labioplastyka. Wyniki i wnioski Korekcję warg sromowych wykonywano przy użyciu monopolarnej diatermii radiochirurgicznej Surgitron S5 firmy Ellman (Cynosure, USA), po ustaleniu zakresu zabiegu z pacjentką i wyznaczeniu planu granic cięcia przed zabiegiem. Zabieg wykonywano w znieczuleniu ogólnym dożylnym. Dzięki lepszej edukacji kobiet na temat możliwości poprawy jakości życia po zabiegu oraz szerszemu dostępowi do specjalistów mogących pomóc w planowaniu operacji, labioplastyka stała się obecnie procedurą częstszą, a zdecydowanie jest główną procedurą z dziedziny ginekologii estetycznej.
Medycyna rdzennych mieszkańców Amazonii
Authors: Spyrka Kinga
Published: April 2023

Od wielu lat w Amazonii postępuje zarówno degradacja środowiska, jak i wycinka lasów tropikalnych pod pastwiska oraz w celu pozyskania drogocennego surowca opałowego i papierniczego. Mniej lasów deszczowych oznacza mniej deszczu, mniej tlenu i zwiększone zagrożenie globalnym ociepleniem. Tak szeroko idące zmiany mogą przyczynić się do globalnej katastrofy i nieodwracalnych zmian. Śmierć Amazonii to nie tylko strata znaczącego źródła tlenu, ale także brak leków i szansy na przełom w medycynie. W pracy omówiono rolę lasów tropikalnych w medycynie oraz zagrożenia wynikające z degradacji środowiska.
Biometric analysis of the area of the foramen magnum using the ImageJ software, and its correlation with the Radinsky and Teixeira formulas
Authors: Aragão José Aderval , Sant’Anna Aragão Iapunira Catarina , Sant’Anna Aragão Felipe Matheus , de Souza Cunha Marcos Guimarães , Dantas Moreno Victor Petersen , Rezende de Brito Victoria , Santana Souza João Vitor , Ribeiro Guerra Danilo , Prado Reis Francisco
Published: April 2023

Introduction: The knowledge of biometrics in the area of the foramen magnum is of importance in the pathophysiology of several disorders of the craniocervical junction, as well as for anthropology, anatomy and forensic medicine. The analysis of the area using image technology is still very scarce in the literature. Objective: Determine the area of the foramen magnum using ImageJ and correlate it with the areas calculated by the formulas of Radinsky and Teixeira. Methodology: 104 human dry skulls of adults were studied, 62 male and 42 female, belonging to the anatomy laboratories of the Universities: Tiradentes (UNIT) and Federal de Sergipe (UFS). To calculate the area of the foramen magnum, the ImageJ software was used, while the measures, length and width, were performed using a digital caliper. The areas calculated by ImageJ were compared to those calculated using the Radinsky and Teixeira formula. Results: The area of the foramen magnum measured by ImageJ ranged from 532.14 to 1135.79mm², with an overall average of 758.71mm². According to Radinsky's formula, the area of the foramen magnum varied from 610.35 to 1233.09mm², with an average of 828.25mm²; and in Teixeira, the area ranged from 633.67 to 1241.29mm², with an average of 840.16mm². The Cronbach's alpha correlating the three methods was equal to 0.950. Conclusion: The calculation of the area of the foramen magnum, using the ImageJ software was significantly close to the area calculated by the formulas of Radinsky and Teixeira (Cronbach's alpha=0.950), proving to be useful for forensic practice. Sexual dismorphism can be found, varying its appearance in literature, but only in relation to its size, but not its shape. However some other authors seem to have not found any sexual dismorphism.
Marsupialisation of bilateral ranula in a buffalo calf
Authors: E Kalaiselvan , Kumar Maiti Swapan , Khan Azam , Kumar Verma Naveen , Singh Mohar , Khan Sharun , Kumar Naveen
Published: April 2023

Ranula refers to accumulation of extra-glandular saliva in the floor of the mouth interfering the normal feeding. A male buffalo calf, age of 6 months had bilateral sublingual sialocele (ranula) showing difficulty to masticate and drink water. Bilateral ranula was excised elliptically to facilitate dynamic fluid/saliva drainage and marsupialisation performed under anesthesia. Animal showed uneventful recovery without any postoperative complications.
Posterior dislocation of the metacarpophalangeal joint of the thumb: case report and review of literature
Authors: María Victoria Machado , Eugenia Torres , Guzmán Ripoll , Maria Lamas , Daniel Wolff
Published: April 2023

Posterior dislocations of the metacarpophalangeal joint of the thumb are due to hyperextension trauma and relatively rare. We present the case of a patient in whom closed reduction was not achieved, requiring open reduction and anchoring of the palmar plate with transosseous pull out technique. A literature review focused on treatment was carried out. All authors agree that closed reduction should be the first therapeutic gesture. If this is not achieved, open reduction should be performed through a dorsal or volar approach, and there is no consensus on which is more effective, nor in terms of management of periarticular soft tissues. Reduction in this case was followed by 2-4 weeks immobilization. Results were generally good, restoring a stable and painless joint, although there might be some degree of joint stiffness.
CRISPR as a novel technique for COVID-19 diagnosis: a review
Authors:   Medical Laboratory Techniques, Al-Hakim General Hospital, Najaf, Iraq, Saleem A. A. , Annooz A. F. ,   Faculty of Medicine, University of Kufa, Najaf, Iraq;, Hadi M. A. ,   Medical Laboratory Techniques, Al-Sadr Medical city, Najaf, Iraq;, Kabla A. H. H. ,   National Advanced IPv6 Centre, Universiti Sains Malaysia, Penang, Malaysia;
Published: April 2023

To this moment, the human coronavirus disease COVID-19 that occurs as a result of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is still a critical case that provokes concern around the world. In January 2022, there were over 300 million infections and over 5 million fatalities from COVID-19. As a countermeasure against this rapid spread, there is a vital need for effective and low-cost diagnosis methods in order to control the danger of this pandemic. CRISPR technology has proved its efficiency in detecting COVID-19 due to its simplicity, specificity and high sensitivity. This paper reviews the state-of-the-art of developing the CRISPR platforms for the purpose of COVID-19 diagnosis and treatment. Limitations and challenges of CRISPR in terms of nucleic acid analytical methods for viral infection diagnosis are discussed. Keywords: Cas protein, COVID-19, CRISPR, RT-PCR, SARS-COV-2
Novel putative ligands of cannabinoid receptors: synthesis and effects on cell signaling and neuronal functions
Authors:   Department of Regulation Cell Proliferation and Apoptosis, Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Senkiv J. , Kryshchyshyn-Dylevych A. ,   Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine;, Khylyuk D. ,   Department of Organic Chemistry, Faculty of Pharmacy with Medical Analytics Division, Medical University of Lublin, Lublin, Poland;, Wujec M. ,   Department of Organic Chemistry, Faculty of Pharmacy with Medical Analytics Division, Medical University of Lublin, Lublin, Poland;, Stoika R. ,   Department of Regulation Cell Proliferation and Apoptosis, Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv;, Irving A. J. ,   School of Biomedical and Biomolecular Science, University College of Dublin, Dublin, Ireland, Lesyk R. ,   Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine;,   Department of Biotechnology and Cell Biology, Medical College, University of Information Technology and Management in Rzeszow, Rzeszow, Poland;
Published: April 2023

Cannabinoid ligands are known to possess neuroprotective actions and may have utility in the treatment of neurodegeneration. The major targets for cannabinoids include the classical CB1 cannabinoid receptor, as well as the novel cannabinoid receptor GPR55 which binds to many synthetic cannabinoid ligands. In this study, novel thiopyranothiazoles 1, 3, 4, 6, and 7 were synthesized and their pharmacological activity as potential cannabinoid-like ligands was evaluated in glioblastoma cells, cultured cortical neurons, and cells of HEK293 line expressing GPR55. Stimulation of protein kinase ERK1/2, MAP-kinases and cAMP response element binding protein (CREB) was evaluated using Western-blot analysis, CREB activation was additionally monitored by means of confocal imaging of nuclear phospho-CREB labeling. Docking simulation confirmed the good affinity of the synthesized compounds to CB1 and CB2 receptors. Striking effects of the chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazol with ethylacetate moiety (3) and isothiochromeno[4a,4-d]thiazole with phenazone fragment (7) on pCREB activation as the indicator of stimulation of the pathway beneficial for neurons survival were observed. Keywords: cAMP response element binding protein (CREB), CB1, CB2, cultured cortical neurons, putative cannabinoid ligands, thiopyranothiazoles
Indices of antioxidant and osmoprotective systems in seedlings of winter wheat cultivars with different frost resistance
Authors:   Yuriev Plant Production Institute, National Academy of Agrarian Sciences of Ukraine, Kharkiv, Yastreb T. O. , Kolupaev Yu. E. ,   Yuriev Plant Production Institute, National Academy of Agrarian Sciences of Ukraine, Kharkiv;,   Poltava State Agrarian University, Ukraine;, Kokorev A. I. ,   Yuriev Plant Production Institute, National Academy of Agrarian Sciences of Ukraine, Kharkiv;, Маkaova B. E. ,   Poltava State Agrarian University, Ukraine;, Ryabchun N. I. ,   Yuriev Plant Production Institute, National Academy of Agrarian Sciences of Ukraine, Kharkiv;, Zmiievska O. A. ,   Yuriev Plant Production Institute, National Academy of Agrarian Sciences of Ukraine, Kharkiv;, Pospielova G. D. ,   Poltava State Agrarian University, Ukraine;
Published: April 2023

The functioning of the stress-protective systems of wheat under the action of cold at the early stages of plant development remains poorly studied. The aim of this work was a comparative study of antioxidant activity and the content of sugars and proline as indicators of osmoprotective activity during cold adaptation of seedlings of seven winter bread wheat (Triticum aestivum L.) cultivars that differ significantly in frost resistance. The 3-day-old etiolated seedlings were hardened at 2°C for 6 days and then frozen for 5 h at -6 or -9°C. Two days after freezing, the survival of seedlings was assessed by their ability to grow. A decrease in ROS content, an increase in the activity of antioxidant enzymes catalase and guaiacol peroxidase and accumulation of sugars in the shoots of high-frost-resistant cultivars during hardening were detected. The absolute values of catalase and guaiacol peroxidase activity correlated positively with the frost resistance of seedlings. The negative correlation between the frost tolerance of the cultivars and the accumulation of proline in the seedlings during hardening was recorded. The possibility of using the studied biochemical indices for frost resistance screening of winter wheat varieties at the seedling stage was stated. Keywords: antioxidant system, cold hardening, frost resistance, osmolytes, oxidative stress, Triticum aestivum
Resultados de la neurólisis como tratamiento del dolor neuropático en pacientes con lesión del nervio ciático. Reporte de casos
Authors: García Bistolfi Mariano , Magno Gonzalo , Saralegui Pilar , Gallucci Gerardo L. , De Carli Pablo , Donndorff Agustín , Rellán Ignacio , Boretto Jorge G.
Published: April 2023

Introducción: La lesión del nervio ciático puede ocasionar desde parestesias e hipoestesias, hasta dolor neuropático severo y parálisis. La neurólisis suele mejorar la función, el dolor y la calidad de vida de los pacientes. El objetivo de este estudio fue evaluar los resultados clínico-funcionales de una serie de pacientes con dolor neuropático por lesión del nervio ciático que no respondieron al tratamiento conservador y fueron sometidos a neurólisis.

Materiales y Métodos: Se analizó retrospectivamente una serie de pacientes sometidos a neurólisis del nervio ciático mayor entre marzo de 2009 y junio de 2018. El dolor pre- y posoperatorio se evaluó mediante la escala analógica visual y la escala de Likert. El tipo de dolor posoperatorio se evaluó con el cuestionario DN4 y la calidad de vida relacionada con la salud, con el cuestionario SF-36.

Resultados: Se incluyó a 8 pacientes. A los 32 meses de seguimiento promedio (rango 14-66), el dolor había mejorado notablemente (promedio de 3 y 1,88 puntos en las escalas analógica visual y de Likert, respectivamente). El cuestionario DN4 arrojó un promedio de 3,75 puntos (rango 2-7). Según el SF-36, la “salud física” fue la variable con peores resultados (promedio 30,15).

Conclusiones: La neurólisis, cuando se indica a pacientes con mala respuesta al tratamiento conservador, es un método que alivia el dolor y mejora la calidad de vida de los pacientes con dolor neuropático secundario a una lesión del nervio ciático.
Aspectos morfológicos del absceso epidural espinal piógeno
Authors: Bazán Pedro Luis , Godoy Adaro Alfredo Osvaldo , Padini Emmanuel , Casco Enrique Alcides , Maruñak Mathias
Published: April 2023

Introducción: El absceso epidural espinal piógeno es la localización de una colección infecciosa dentro del canal raquídeo, por fuera del saco dural. El diagnóstico es difícil y las consecuencias son devastadoras a causa de la compresión o el compromiso vascular. La resonancia magnética tiene una alta sensibilidad y especificidad diagnósticas que aumentan si se administra un medio de contraste. Los objetivos de este estudio fueron: determinar la reproducibilidad inter- e intraobservador, y discriminar los distintos parámetros y diferencias entre especialidades.
Materiales y Métodos: Veintisiete observadores independientes evaluaron 5 parámetros: región, ubicación, compromiso, asociación y perivertebral, absceso extravertebral anterior, lateral o posterior. Se analizaron 35 casos en tres oportunidades, se utilizó el coeficiente kappa.
Resultados: El nivel de acuerdo global intra- e interobservador global fue kappa 0,76; los valores obtenidos fueron: región 0,94; ubicación 0,88; compromiso 0,55; asociación 0,67 y perivertebral 0,77. Los tres primeros parámetros dan noción de volumen y los dos últimos reflejan la presencia de focos infecciosos vertebrales por fuera del conducto.
Conclusiones: La clasificación morfológica propuesta es de uso simple y tiene una muy buena tasa de reproducibilidad intra- e interobservador. Los parámetros con mayor reproducibilidad son: región y ubicación (>0,87).
Mucopolisacaridosis tipo VI: a propósito de un caso
Authors: Besse Micaela , Baigorria José Francisco , Ambrosini José Leandro , Baldasarre Ricardo , Rosado Pardo José Antonio , Sarotto Aníbal José
Published: April 2023

La mucopolisacaridosis tipo VI o síndrome de Maroteaux-Lamy se produce por la deficiencia de la enzima arilsulfatasa B que ocasiona la acumulación intracelular de dermatán sulfato. El riesgo de compresión medular es particularmente elevado y muy frecuente en la unión occipito-cervical. La terapia de reemplazo enzimático ha sido esencial para los pacientes con esta enfermedad; sin embargo, no tiene efecto sobre las alteraciones esqueléticas, y su impacto sobre la estabilidad espinal está aún en estudio. Se sugiere un examen anual (evaluación neurológica, radiografías, resonancia magnética y potenciales provocados somatosensitivos) y, en caso de anomalías, cada 6 meses. Pese al alto riesgo anestésico, la mielopatía y los síntomas progresivos indican la necesidad de una descompresión quirúrgica. Presentamos a una niña de 12 años con mucopolisacaridosis tipoVI tratada con terapia de reemplazo enzimático desde los 7 años, que acude a la consulta con síntomas compatibles con mielopatía cervical alta progresiva. Fue sometida a una descompresión y artrodesis occipito-cervical con ampliación del foramen magno. Esta enfermedad es infrecuente; por lo tanto, es imperativo el seguimiento multidisciplinario del paciente, así como conocer el riesgo de compresión medular y su oportuno tratamiento quirúrgico a cargo de cirujanos espinales.
Conceptos actuales sobre el tratamiento ortésico en el método Ponseti
Authors: Masquijo Julio Javier , Allende Victoria
Published: April 2023

El método Ponseti se ha convertido en el patrón de referencia para el tratamiento del pie bot, con excelentes resultados funcionales en el seguimiento a largo plazo. El cumplimiento del protocolo de férula es fundamental para mantener la corrección obtenida y el éxito terapéutico a largo plazo. Existen múltiples férulas para mantener la corrección y prevenir la recurrencia. En este artículo,proporcionamos una revisión de las férulas utilizadas para el pie bot, y analizamos sus ventajas y desventajas, así como la evidencia sobre cada una.
Tratamiento endoscópico de la espondilodiscitis lumbar. Reporte de un caso y revisión bibliográfica
Authors: De Zavalía Máximo , Sauri-Barraza José-Carlos , Gobbi Enrique , Bañuelos Aluzzi Carlo Enrico , Carral Robles de León Eugenio , Callejas Ponce Eduardo
Published: April 2023

Se describe el caso de un hombre de 62 años de edad, con múltiples comorbilidades que concurre a la consulta por dolor lumbar severo compatible con espondilodiscitis de T12-L1-L2. Se realizó una endoscopia con abordaje posterolateral izquierdo con técnica adentro-adentro para fines diagnóstico y terapéutico. Se aisló un germen y se administró un tratamiento antibiótico específico.Dada la buena evolución clínica del paciente, fue dado de alta a los 7 días de la cirugía, con buen manejo del dolor y antibióticos intravenosos en el domicilio. Se presenta una breve revisión bibliográfica.
Vástagos femorales cortos para el reemplazo total de cadera primario en pacientes jóvenes. Resultados clínicos y biomecánicos*
Authors: Lucero Carlos Martín , Slullitel Pablo A. , Díaz-Dilernia Fernando , Zanotti Gerardo , Comba Fernando , Buttaro Martín
Published: April 2023

La artroplastia total de cadera es una cirugía eficaz para tratar la artrosis. Con el aumento de la necesidad de una mejor calidad de vida, este procedimiento se está realizando en pacientes más jóvenes. Pero, con la mayor expectativa de vida, también crece la demanda de múltiples cirugías de revisión para el mismo paciente. Esto plantea desafíos técnicos debido a la pérdida de hueso. Existe una necesidad creciente de identificar implantes duraderos y altamente funcionales que sean adecuados para la revisión futura. Aunque los vástagos femorales cementados eran la opción principal en el pasado, los vástagos femorales no cementados han logrado una fijación a largo plazo y excelentes resultados. Sin embargo, aún se pueden mejorar algunos problemas relacionados con la fijación. Los vástagos femorales cortos han sido desarrollados para abordar algunos de estos desafíos, mientras se mantienen los buenos resultados obtenidos con los vástagos convencionales. En este artículo, se analiza la experiencia tras 10 años de uso de vástagos femorales cortos en cirugías de cadera en pacientes jóvenes. Se comparan los resultados biomecánicos y la preservación ósea femoral, se reportan los resultados posoperatorios en relación con el regreso al deporte, y se evalúan las complicaciones relacionadas con su uso. El empleo de vástagos cortos en cirugía primaria de cadera brinda múltiples ventajas. La indicación de este tipo de implante está justificada en pacientes jóvenes y activos, con el objetivo de reproducir los resultados de los implantes convencionales con un menor consumo de hueso y la posibilidad de una revisión futura.
Hospitalized Infants With Medical Complexity Experience Slow Acquisition of Gross Motor Skills
Authors: Pflock Kelly A. , Fragala-Pinkham Maria , Shulman Julie , Babcock Breanne Dusel
Published: April 2023

OBJECTIVES

The progression of infant gross motor development during an acute hospitalization is unknown. Understanding gross motor skill acquisition in hospitalized infants with complex medical conditions is necessary to develop and evaluate interventions that may lessen delays. Establishing a baseline of gross motor abilities and skill development for these infants will guide future research. The primary purposes of this observational study were to: (1) describe gross motor skills of infants with complex medical conditions (n = 143) during an acute hospitalization and (2) evaluate the rate of change in gross motor skill development in a heterogenous group of hospitalized infants with prolonged length of stay (n = 45).

METHODS

Gross motor skills in hospitalized infants aged birth to 18 months receiving physical therapy were evaluated monthly using the Alberta Infant Motor Scale. Regression analysis was completed to assess rate of change in gross motor skills.

RESULTS

Of the 143 participants, 91 (64%) demonstrated significant motor delay at initial evaluation. Infants with prolonged hospitalization (mean 26.9 ± 17.5 weeks) gained new gross motor skills at a significant rate of 1.4 points per month in Alberta Infant Motor Scale raw scores; however, most (76%) continued with gross motor delays.

CONCLUSIONS

Infants with complex medical conditions admitted for prolonged hospitalization frequently have delayed gross motor development at baseline and have slower than typical acquisition of gross motor skills during hospitalization, gaining 1.4 new skills per month compared with peers acquiring 5 to 8 new skills monthly. Further research is needed to determine effectiveness of interventions designed to mitigate gross motor delay in hospitalized infants.
Aconitum lasiocarpum and A. variegatum (Ranunculaceae) populations near the eastern limits of their ranges in the lowlands of Ukraine
Authors: Melnyk V. I. , Baransky O. R. , Batochenko V. M. , Volodymyrets V. O. , Dovhopola L. I. , Melnyczenko N. V.
Published: April 2023

The study of the ranges, habitats and current state of rare and threatened species of plants is a relevant task of ecological research. The paper presents the results of the study of habitats and current state of populations of two rare species of Ukrainian flora Aconitum lasiocarpum (Rchb.) Gáyer and A. variegatum L. (Ranunculaceae) in the lowlands of Ukraine. These species are members of the mountain element of the flora of lowlands of Ukraine and glacial relics, which descended from the Carpathians Mountains to the lowlands of Ukraine during glaciation. Aconitum lasiocarpum is a rare species of European flora, included to the Red Data Books of the Czech Republic and Slovakia, Poland and Ukraine. Unlike the well studied A. lasiocarpum populations in the main part of the range in the Carpathian Mountains, local populations of this species near the eastern limit of the range in the lowlands of Ukraine remain undescribed. In these exclaves of the range in the lowlands of Ukraine A. lasiocarpum is a glacial relic. Here it grows in alder forests Ribo nigri-Alnetum ordo Alnion glutinosa alliance. Lowland A. lasiocarpum populations consist of 1000–10000 adults with a significant number of young individuals. In the past lowland A. lasiocarpum populations occupied a much large area. Deforestation and drainage melioration led to reduction of the populations. Taking into account the low number of glacial relic populations at the eastern limit of the range of A. lasiocarpum, all localities of this species in the lowland part of the range in Ukraine must be taken under protection in situ. Aconitum variegatum L. grows in wet alder and oak forest and in areas with hazel shrubs. The populations of this species in lowlands of Ukraine occupy a very small area and are characterized by low numbers of individuals. In the past populations of this species in the lowlands of Ukraine occupied a larger area. As a rare species of the Ukrainian flora A. variegatum deserves to be included to the Red Data Book of Ukraine. We propose to protect the unique population of A. variegatum near Susk village in Rivne region as a botanical reserve.
Features of the seasonal dynamics of airborne fungal spore concentrations in Ukraine
Authors: Reznik Y. V. , Yermishev O. V. , Palamarchuk O. V. , Bobrovska O. A. , Rodinkova V. V.
Published: April 2023

Fungi represent a distinct kingdom of ubiquitous living beings. Most other organisms are constantly in contact with elements of the fungal body. In particular, the widespread vegetation of fungi in the environment, their sporulation and the further spread of spores and mycelia by air currents make the contact of fungal particles with human respiratory organs inevitable. This can lead to the development of sensitization and allergies. Therefore, the aim of the presented study was to determine the taxonomy of airborne fungal spores, the qualitative and quantitative changes in this composition at different times of the year compared with previous sporulation seasons, as well as the prevention of allergic diseases. The study of fungal sporulation was carried out from 2011 to 2021 by volumetric method using Burkard trap of a Hirst type in a 24-hour mode (from February to November). The device was installed on the roof of the chemical building of the National Pirogov Memorial Medical University, Vinnytsya. Reading of the microscopic slides obtained from air samples was carried out using light microscopes with a magnification of 400 and 1000 by the method of 12 vertical transects. It was found that spores of various taxonomic groups of fungi, namely, of Asco- and Basidiomycetes were observed throughout the growing season from March to October with the highest concentrations in mid and late summer. Thus, in June, July and August, peak concentrations of spores of the fungi Ganoderma, Coprinus, Cladosporium were observed; in July, September and October – of Ustilaginales; from July to November – of Alternaria, Epicoccum; in October – of different Basidiospores, and also Periconia, Stemphylium and Uredinales; in September – of Agrocybe. Among all studied micromycetes, concentrations of Cladosporium spores were the highest. However, significant sporulation persisted even in the autumn period, which made fungal spores a specific causative agent of airborne respiratory diseases at this time, especially against the background of low pollen concentrations. Climate change can lead to modification in the length of the fungal growing season. This information should be taken into account when predicting the symptoms of seasonal allergies in the population.
Effect of Echinacea purpurea and Silybum marianum seeds on the body of rats with an excessive fat diet
Authors: Lieshchova M. A. , Brygadyrenko V. V.
Published: April 2023

The impact of excess fat and high-calorie intake on the human body is an acute problem for many economically developed countries. Modelling the effects on the health of rats of supplementing their diet with crushed seeds of Echinacea purpurea (L.) Moench and Sylibum marianum (L.) Gaertn was carried out in a laboratory experiment. In the control group of animals, body weight increased by 700 mg/day, with the addition of E. purpurea seeds – by 1394 mg/day and with the addition of S. marianum seeds – by only 155 mg/day. A hypercaloric diet supplemented with E. purpurea caused a significant decrease in the relative weight of the liver, thymus, spleen, stomach, and brain. The supplementation with S. marianum seeds to the diet of animals significantly reduced only the relative weight of the thymus. Adding E. purpurea to the diet caused a strong increase in blood alkaline phosphatase activity, an increase in the cholesterol content, and a sharp increase in the atherogenic index. The seeds of S. marianum increased the alkaline phosphatase activity, reduced the glucose concentration, and triglycerides, significantly reduced the atherogenic index and lowered the C-reactive protein concentration in the rats’ blood when compared with the control group. The seeds of E. purpurea contributed to an increase in the erythrocyte and lymphocyte number in the blood, and the seeds of S. marianum – to a decrease in the thrombocyte concentration. The research results show the possibility of wider use of S. marianum fruits as a dietary supplement in the diet of patients with hypertension and impaired liver function.
Foliicolous Lichens of the Fiji Islands
Authors: Farkas E.
Published: April 2023

Eighteen species of foliicolous lichens have been mentioned earlier from the Fiji Islands in various literature sources and based on collections since 1860. Current records originate from the collections of Göran Thor from 1985 and Sarolta and Tamás Pócs from 2003. G. Thor visited lowland rainforests of Island Viti Levu, S. and T. Pócs collected also in higher elevations (up to ca 1,000 m) in submontane, montane and montane mossy (cloud) forests on Kadavu, Taveuni and Viti Levu Islands. These relatively small collections (of ca 300 and 150 leaves, respectively) resulted in 78 species of the 85 lichen species known today, among them 67 species are new for the foliicolous lichen flora of the area in this publication. New taxa described are Phylloblastia taveuniensis Farkas, Porina kadavuensis Farkas, furthermore the genus Tamasia Farkas (Ramalinaceae) and species Tamasia fijiensis Farkas containing cyanobacterial photobiont.
Determination of influential springback parameters in U-bending test
Authors: Dessie Jemal Ebrahim , Lukacs Zsolt
Published: April 2023

U-bending tests are the most common method to predict springback and are influenced by the process and geometrical variables in addition to material behaviour. It needs a numerical study at a high level with many variables to reduce try-out time and loop. In this study, the U-bending test of DC01 steel has been researched numerically and experimentally to govern the influential parameters. The numerical analysis was conducted using AutoForm-Sigma code. The die radius has an excessive influence on the change of flange angle than the punch radius, but the punch radius has the greatest influence on the variation of the sidewall angle. The coefficient of friction played a great impact on both flange and sidewall angle deviation and its influence grows stronger as the blank holding force increases.
Model Relasi Islam-Kristen pada Masa Nabi: Sebuah Tinjauan Historis
Authors: Siddiq Akhmad
Published: April 2023

Attempts to build inter-religious harmony obtained influential obstacles within social relationship that is regularly based on never-ending ideological discourses. Every religion comes with its own basic faith and claim of truth. Even though, this claim should not normatively exclude the faith of others. In other word, religious believers could not assert their own faith to blame other different faiths. This paper argues that inter-religious harmony, especially between Islam and Christianity, is not only based on doctrinal-ideological argument but also historical evidences. This research will portray the relations between Islam and Christianity in the era of the Prophet Mohammad that could be illustrated in three periods: (1) pre-revelation, (2) the period of Mecca, and (3) the period of Medina. The paper will also explain the Islam-Christian relation model in the era of the Prophet by using historical-critics and hermeneutical-phenomenology.
Pengaruh Tingkat Kecerdasan Ruhaniah terhadap Penyesuaian Sosial Remaja (Studi Deskriptif Kualitatif pada Siswa SMK Negeri 1 Majalaya)
Authors: Nuraeni Intan , Gojali Muhtar , Sari Tias Febtiana
Published: April 2023

In development, adolescents experience a period of transition, which some people view as a period of chaos. Therefore, adolescents need adequate ability to interact in order to be able to establish a harmonious relationship with their environment. In this case, the success of the interaction is influenced by the ability to adapt to the environment. Social adjustment can help teenagers to achieve good interactions. Spiritual intelligence is the essence of all intelligence that is in divine values. This study aims to understand the influence of the level of spiritual intelligence on the social adjustment of adolescents in SMK Negeri 1 Majalaya by using a qualitative descriptive research method by interviewing six sources with an age range of 14 years to 17 years who attend SMK Negeri 1 Majalaya. From the data it is known that spiritual intelligence has an influence on the social adjustment of adolescents in SMK Negeri 1 Majalaya. In addition, the research data shows that the six resource persons in this study have good spiritual intelligence and make good social adjustments. Thus, the conclusions in this study indicate a positive relationship between the level of spiritual intelligence on the social adjustment of adolescents at SMK Negeri 1 Majalaya. It is hoped that future researchers will use other methods so that more accurate results are obtained.
Agama dan Kekerasan Politik di Indoensia (Studi pada Kasus Pemberitaan di Media Internet)
Authors: Kasim Muhammad
Published: April 2023

This paper discusses religion and political violence in Indonesia. The main problem in this research is the existence of political views which say that religion can be used as a tool in achieving power, so that violence often appears as a side effect. This research question is contained in the first two main questions, how violence in the name of religion can occur from a political perspective. Second, how is the phenomenon of cases of political violence in the name of religion in Indonesia. The method in this research is a case study method on several news published as news on the internet. The main sources in this research are the news about political violence in the name of religion which is published in Kompas.com, detiknews.com, people's minds.com, and CNN.com newspapers. Secondary sources in this research are articles discussing religion and political violence published in scientific journals. The results of this study come to the conclusion that religion is often used as a tool to achieve power in relationships. Then physical or non-physical violence occurs as a result which is a political act. Physical violence occurred in the internal attacks experienced by minority groups from the majority group such as attacks on Christians in Aceh, and non-physical violence occurred with the practice of applying rules that seemed to have been trumped up by government apparatus on church building regulations in Aceh.
Telaah Metodologis Kitab Tafsir Irsyad al-‘Aql al-Salim Ila Mazaya al-Kitab al-Karim Karya Abu al-Su’ud Al-‘Imadi
Authors: Basyiruddin Muhammad Hafizh , Nugraha Sandi , Zulaiha Eni
Published: April 2023

The purpose of this paper is to analyze Abu al-Su'ud Al-'Imadi's exegetical manual, Irsyad al-'Aql al-Salim ila Mazaya al-Kitab al-Karim, focusing on the manual's sources of interpretation (mashdar), techniques of interpretation (manhaj), and interpretation orientation (ittijah). The mufassir's life story, his scientific discoveries, and the context of the commentary's composition are all briefly covered. This method of research is qualitative and takes a literature-based approach. From the perspective of the source, Abu al-Su'ud Al-'Imadi's commentary Irsyad al-'Aql al-Salim ila Mazaya al-Kitab al-Karim falls into the category of interpretation bi al-Ra'yi; from the perspective of the method, it employs the tahlili; and from the perspective of the orientation, it includes the lughawi. Abu al-Su'ud al-'Imadi was a scholar who lived during the Ottoman Empire's golden age, when the population enjoyed economic success, political stability, and scientific advancement. This seems to be the driving force behind Abu al-interpretation Su'ud's from a linguistic perspective. His ardor for the Arabic language and literature, which has elevated him to the level of an expert in the field, is another important factor in the linguistic focus of his interpretations (lughawi).
Filozoficzna droga kard. Mariana Jaworskiego: od metafizyki ogólnej do szczegółowej i stosowanej
Authors: Mikucki Kazimierz
Published: April 2023

Artykuł jest próbą syntetycznego ujęcia dorobku Mariana Jaworskiego w aspekcie zasadniczego sposobu i kierunku jego myśli oraz najważniejszych, formułowanych przez niego idei, obecnych zwłaszcza w jego ostatniej książce, stanowiącej trzeci tom jego prac, w którym zawarte są w zdecydowanej większości artykuły najnowsze. Są one świadectwem drogi, jaką przebył w swym sposobie rozumienia filozofii i problemów przez nią podejmowanych, potwierdzeniem pewnego procesu ewolucji, jaka miała miejsce w jego życiu na polu tej nauki. Świadczą o niej dość wyraźnie zarysowujące się trzy fazy w jego aktywności filozoficznej pod względem metodologicznym oraz podejmowanej problematyki. Pierwszą stanowiły  zainteresowania metafizyką ogólną. Kolejna związana była z realizowaniem idei metafizyk szczegółowych i stosowanychw oparciu o narzędzia poznawcze metafizyki ogólnej w  podstawowych naukach filozoficznych (filozofia religii, antropologia filozoficzna i filozofia Boga). Końcowa natomiast wyrażała się w realizacji powyższej idei metafizyk  w dyscyplinach bardziej partykularnych, obejmujących filozofię chrześcijaństwa i jego niektórych fenomenów,jak modlitwa i życie konsekrowane, oraz filozofię zjawisk spoza kręgu ściśle chrześcijańskiego (cierpienie, humanizm, dialog).
STEAM integration
Authors: Taylor Simon , Lowe Paul
Published: April 2023

There has been growing interest to establish curriculum integration in secondary schools due the promotion of relevant contexts used in programmes. This project has examined the role of a STEAM programme with junior secondary school students using future focussed inquiries which included Science, Environment, Technology, the Arts, and Mathematics. To explore the potential role of STEAM programmes, a group of teachers from a New Zealand and a Japanese international school participated in a design-based intervention. While curriculum integration has been a feature of learning in many primary schools, secondary teachers who are usually subject specialists are faced with the challenge of how to design and facilitate cross-curricular inquiries using STEAM. To meet this challenge, the teachers and curriculum developers considered the interface between their conceptions of cross-curricular inquiry and taking practical steps to implement such a programme. The project investigated pedagogies to develop skills in cross-curricular project work, new themes to exemplify integrated STEAM learning, and a model of professional development that would support this approach.
Promoting a broad curriculum: Special series introduction
Authors: Earl Rinehart Kerry
Published: April 2023

N/A
Dynamics of indicators characterizing the health of children in the territory of military conflict. The impact of rehabilitation measures: cohort study
Authors: Levchin Artem M. , Ershova Irina B. , Rogovtsova Alyona G.
Published: April 2023

Background.There are still understudied issues concerning the health indicators of children who are in conditions of conducting warfare in primary school age. Objective. The aim of the study is to evaluate comprehensive rehabilitation measures to optimize health indicators (physical, functional and mental capacity parameters) of primary school children in conditions of military conflict.

Methods.An examination of 419 elementary school children was conducted in the period from March 2022 to September 2022 including. The main group: 128 children, who lived in the territory of military operations. Control group: 291 children who lived peaceful territories. The indicators (body mass index, Robinson index, vital index, strength index, V.A. Shapovalova power index and mental capacity of children according to the results of V.Ya. Anfimov correction task) were compared before the start of the developed comprehensive rehabilitation program and 6 months after the start of its implementation.

Results.It was found that all elementary school children who lived in locations of military conflict had a decrease in physical and functional parameters of varying degrees of severity, as well as indicators of mental capacity. The comprehensive rehabilitation program promoted to the normalization of the studied indicators in evacuated (57/86, 56%) children in comparison with children who remained in the locations of military operations (43/70, 49%). The studied indicators had the highest recovery rates at the age of 7-8 years. The most vulnerable was a subgroup of 9-10 years old boys who permanently living in conditions of conducting warfare. The development and implementation of the comprehensive integration program using individual rehabilitation routes had an optimizing effect on the studied indicators of physical and functional conditions, as well as cognitive performance in 101 children of the main subgroups, which amounted to 78.9%.

Conclusion.Under the influence of the comprehensive integration rehabilitation program, optimization of health indicators was observed in children living in locations of conducting warfare. The most pronounced effect was observed in children who left the territories of shelling as a result of evacuation to Rostov-on-Don.
Sprawozdanie z II Międzynarodowej Konferencji Wschodnioznawczej „Przestrzeń postradziecka: procesy integracji czy dezintegracji”, Toruń, 17–18 października 2013 roku
Authors: Ambroziak Tomasz
Published: April 2023

Report on the 2nd International Conference on the Post-Soviet Space “Przestrzeń postradziecka: procesy integracji czy dezintegracji” [Post-Soviet Space: a space of integration or disintegration], Toruń, October 17th–18th, 2013
Eric Hobsbawm, Jak zmienić świat. Marks i marksizm 1840–2011, Wydawnictwo Krytyki Politycznej, Warszawa 2013, ss. 461
Authors: Berlińska Paulina
Published: April 2023

How to change the world. Marx and Marxism – 1840–2011
Многопартийность и плюрализм мнений как движущаяся сила развития демократического общества
Authors: Саидов Акмаль Х.
Published: April 2023

Multi-party pluralistic viewpoints as a drive of democratic society’s development
PREDICTION OF VIRTUAL FATIGUE PARAMETERS OF FLY ASH, BORON NITRIDE, AND SUGARCANE FIBER-REINFORCED EPOXY COMPOSITE
Authors: Gopalan Venkatachalam , Suthenthiraveerappa Vimalanand , Govindaraman Loganathan Thozhuvur , Senthilvelan Srinath , Ramu Chandrasekkaran Vijiyashree
Published: April 2023

Composite materials are blended in such a way that their properties are multi-fold their components' properties. The use of green materials, as components, makes the product eco-friendly and that needs to prove product quality. This work identifies the fatigue limit of 3D-modeled composite laminate and virtually predicts the fatigue life cycle under a certain fatigue load. The 3D model is assigned with the properties of the different combinations of epoxy composite and fatigue analysis is carried out. The epoxy composite considered in the analysis has fly ash, boron nitride (BN), and sugarcane (SC) fiber as reinforcements. A central composite design (CCD) method under response surface methodology (RSM) has been used to develop the experimental trials. The regression equations of the RSM model are utilized to study the influences of reinforcements and their wt. % in the determined fatigue limit and fatigue life cycle. The results show that the fatigue limit of the composite is maximum when the wt. % of fly ash and BN is 2% and 1%, respectively. However, the fatigue life cycle is maximum with 2% wt. of sugarcane (1982 × 103 cycles) amidst minimum fly ash and BN. This work emphasizes the blending of specific wt. % of reinforcement in epoxy has significant control on the fatigue properties of the composites.
NUMERICAL DESIGN OF ASYMMETRIC POROUS MATERIALS WITH TARGET PROPERTIES
Authors: Paisley Benjamin , Riasi M. Sadegh , Konangi Santosh , Yeghiazarian Lilit
Published: April 2023

Numerical tools have become ubiquitous in design of manufactured porous materials. Many methods have been developed for imaging, reconstruction, material property estimation, and generation of materials in a virtual environment with the ultimate goal of understanding the connection between the synthesis process, material microstructure, and material properties. In previous works, we presented a new random field-based generation technique called adjustable level cut filtered Poisson field (ALCPF). We paired the ALCPF technique with a flow simulation method, the pore topology
method (PTM), to compute material properties and verify that targets have been attained. Building on our earlier work
where we demonstrated the ability of ALCPF to efficiently generate a wide variety of homogeneous microstructures,
we pursue three new goals. First, we extend ALCPF to produce heterogeneous asymmetric porous materials with a
target pore size gradient. Second, we demonstrate the capability of asymmetric-ALCPF to control both solid and void spaces by generating virtual asymmetric materials with different types of solid matrix geometries and void space pore size gradients. Third, we use these materials to assess the accuracy of PTM results in comparison with the solution
from a direct numerical simulation. This work demonstrates that the ALCPF method successfully generates porous
microstructures with desired asymmetric geometry with less than 4% error compared to target pore size gradient. Also, PTM estimates permeability with an average error of less than 7% compared to direct numerical simulation results.