bluuebunny/crossref_metadata_2025 huggingface dataset:
Air-side heat transfer enhancement by self-agitators
Authors:   , Li Kuojiang
Published: April 2021

Airfoil-based self-agitators (AFAs), bio-inspired rectangular-shaped self-agitators (RSAs), and caudal-fin inspired hourglass-shaped self-agitators (CHSAs) were installed inside plate-fin heat exchanger. The heat transfer enhancement and pressure drop characteristics of these AFAs, RSAs, CHSAs design were experimentally investigated and compared with the clean channel case. We found that the self-agitators vibrate periodically and generate vortices, which enhance flow mixing and thus heat transfer performance. For the chosen heat sink and assigned working conditions, the best heat transfer performance was obtained with four rows AFAs, which caused an 80% increase in overall Nusselt Number over the clean channel at same Reynolds Number, and a 50% rejected heat increase at the same pumping power due to the strong longitudinal vortices generated by the presence of the AFAs. Experiments were conducted at a wide range of Reynolds numbers from 400 to 10000, which covered laminar-transitional-turbulent regime with CHSAs. Experimental correlations of the pressure drop as a function of dimension parameter and friction factor and Nusselt number as functions of dimensionless ones have been proposed. Mutual coupling motions and effects of multiple-row flapping CHSAs in parallel and tandem configurations were studied by using a high-speed camera. A stereo Particle Image Velocimetry (PIV) system was used to conduct detailed flow field measurements to quantify the flow mixing level. For the chosen plate-fin heat exchanger and assigned working conditions, the best heat transfer performance was obtained with six-row CHSAs with a pitch of 25mm, which caused a 200% increase in the Nusselt number over the clean channel at the same Reynolds number. However, the best overall performance was obtained with twelve-row CHSAs with a pitch of 12.5mm, which caused a 68% enhancement in thermal-hydraulic characteristic compared to the clean channel at the same Reynolds number.
Killing "woman" : gender and violence in selected plays by Sheila Callaghan and Marisa Wegrzyn
Authors:   , Busselle Kate
Published: April 2021

One of the most popular manifestations of spectacle in the theatre is violence. Frequently, violence on the stage manifests in the form of violence towards women at the hands of men. As a woman violence and intimacy designer, I wanted to find works that challenged and subverted this popular staging and question what those works have to say about gender, violence, and gender performance. Two playwrights who are challenging long-held dramatic representations of women and violence are playwrights Sheila Callaghan and Marisa Wegrzyn. Callaghan and Wegrzyn are two of the founders of the Kilroys, a group of femme-identifying literary managers, playwrights and producers living in Los Angeles, California, who organized in 2013 to promote the work of female and trans playwrights. Not only do their most representative works contain several acts of violence committed by women characters, but the nature of these portrayals of violence strays from "traditional" representations of violence. Using a range of relevant theoretical lenses, I will analyze four representative plays -- Sheila Callaghan's Roadkill Confidential and That Pretty Pretty; or, the Rape Play and Marisa Wegrzyn's The Butcher of Baraboo and Killing Women to investigate how these works disrupt essentialist notions of gender and identity, with special attention to the implications and meanings of their dramatic representation of onstage acts of violence committed by women. Through critical analysis of these works, this dissertation seeks to increase understanding of how these performances of violence challenge heteronormative notions of gender. As the context in which these violent acts occur is crucial, this dissertation analyzes the gendered implications of the setting, plot, and characterizations of each work. Additionally, this dissertation explores how designing the violence within these moments may help reinforce the gender disruption created by Callaghan and Wegrzyn.
Quantitative analysis of impact of response to intervention on 2019 sixth-grade rural public middle school Missouri assessment program performance by free and reduced-price lunch eligibility
Authors:   , Collins Tiffani J.
Published: April 2021

This study focused on the impact of response to intervention on 2019 sixth-grade rural public middle school Missouri Assessment Program performance by free and reduced-price lunch eligibility. Response to intervention was used to decrease learning gaps for students. Missouri Assessment Program performance was used as an accountability measure for Missouri public school students. The researcher used the Missouri Assessment Program, a standardized assessment given to Missouri public school students in grades three through eight. The annual test includes mathematics and English language arts in grades three through eight and science in grades five and eight. This research focused on mathematics in grade six. This study concluded that there were significant differences in student scores based on: free and reduced lunch eligibility; race and ethnicity; response to intervention received; and response to intervention level. Moreover, the researcher found that students in response to intervention Level 2 are effectively identified to receive academic assistance. This seemed to be a stronger identifier than free and reduced-lunch eligibility and race.
Birth order and gender : differential parental investment in Medieval England and France in the eleventh, twelfth, and thirteenth centuries
Authors:   , Fields Jessica D.
Published: April 2021

This dissertation addresses the question: will parents invest differently in their children based on gender and birth order? Using parental investment theory and four major sets of outcome variables--child survival, parental investment (through wealth, land, and titles), marriage, and reproductive success--this question will be examined in an historic population, medieval England and France in the eleventh, twelfth, and thirteenth centuries. The results presented in this dissertation shows that parents were willing to invest in their offspring differentially with a preference for sons over daughters and older children over younger children. Historic populations provide a microcosm in which to study human behavior. The findings in this dissertation have implications for both evolutionary ecology and evolutionary demography.
A history of 'in loco parentis' in American high education
Authors:   , Forrest Craig Robert
Published: April 2021

From the establishment of institutions of higher education in Colonial America until the 1970s, college administrators have acted in loco parentis, or as legal guardians of students "in the place of parents." Under the legal regime of in loco parentis, society and the legal system required school administrators to look after the educational, moral, and behavioral growth of students. In order to fulfill their obligations to students in loco parentis, administrators put in place curricular requirements and campus rules, and they were granted the disciplinary leeway of students' natural parents or guardians to enforce those requirements and rules. Through a series of court cases in the 1960s an 1970s, the legal requirements imposed upon administrators was removed and students enrolled in colleges and universities were granted legal adulthood. Through research of primary and secondary sources, this dissertation examines the history of in loco parentis in American higher education. It discusses the evolution of the role college administrators played in loco parentis over three centuries, and how higher education itself evolved as American society changed. As schools grew in size and expanded in scope, administrators retreated from, or were stripped of, their in loco parentis responsibilities. By the mid-1970s, American college students were seen by the courts and society as legal adults with constitutional rights, and in loco parentis in American higher education was dead.
Who is the ideal worker? How gendered organizations adversely impact women's promotability and development
Authors:   , Steele Clarissa R.
Published: April 2021

Women tend to earn fewer promotions (Roth et al., 2012) and receive fewer developmental opportunities (King et al., 2012) than men, but little research explains why. I explore the stereotype of the ideal worker, someone who meets their supervisor's expectations and has the potential to be promoted to the top levels of their organization over their career, as one reason for this disparity. I propose that supervisors use this stereotype to assess employee promotability and developmental opportunities. I explore the attributes of the ideal worker stereotype using the theory of gendered organizations (Acker, 1990, 1992), which suggests that firms operate from a masculine perspective because men tend to create and lead organizations. I find that the attributes of the ideal worker are broader than suggested by the theory of gendered organizations and past research on the ideal worker, but that these attributes are not perceived as masculine. In addition, I find no differences between how men and women are rated in terms of promotability, recommended development, and the extent to which they exemplify the attributes of the ideal worker. However, the extent to which employees exemplify ideal worker attributes predicts promotability ratings and development recommended for them. Sexism, an individual difference among raters, moderates the relationship between employee gender and outcomes such that women receive lower ideal worker ratings and less recommended development when raters have high sexism beliefs. I also find that the implicit (unconscious) associations between ideal worker attributes and gender role stereotypes affects recommended development such that those with masculine implicit associations give more development to female employees. My dissertation presents future research opportunities to further investigate the ideal worker stereotype and its impact in the workplace.
How female principals nurture adult learning opportunities in successful high schools with challenging student demographics
Authors:   , Woodward Dana Moad
Published: April 2021

Based on Cueva's (2010) learning strategies, this study investigated adult learning strategies successful high school female principals use to nurture adult learning opportunities at their schools in the state of Missouri. Public high schools were selected based on their 2019 Missouri School Improvement Program (MSIP 5) performance standards and indicators. Their principals were asked to complete a survey online and self-select to be interviewed. The findings indicated that principals take their role as instructional leaders seriously and seek to use learning strategies for understanding, conversation, and action. The most frequently used adult learning strategy is Nurturing Place while the least used is Creative Expressions. The principals desire more time and resources to help their teachers learn.
Evidence-based practice self-efficacy of speech-language pathologists across settings
Authors:   , Tilmon Misty
Published: April 2021

The purpose of this mixed-methods sequential explanatory study was to explore self-efficacy of speech-language pathologists (SLPs) employed in various settings. Self-efficacy of master's level SLPs was compared across settings to determine if differences existed in each of four experience groups. Self-efficacy ratings were also compared based on degree held, area of practice, and years of experience. Participants (n = 342) completed a survey containing 10 demographic questions, 11 items from Salbach and Jaglal's (2010) Evidence-Based Practice Confidence (EPIC) scale, and 2 open-ended questions regarding factors impacting self-efficacy. Participants (n=34) completed semi structured interviews to further explore factors influencing self-efficacy. No significant difference was noted in self-efficacy of master's level SLPs among settings. There was a significant difference between self-efficacy ratings based on degree held and years of experience. A significant difference in self-efficacy was found based on practice category (i.e., identification of knowledge gap, critical appraisal of research, development of treatment plans based on evidence, clinical judgment, and client preferences). Qualitative analysis revealed graduate program and post-graduate factors which impacted self efficacy ratings both positively and negatively.
The lower senses in early Netherlandish epiphany altarpieces
Authors:   , Meade Pachomius (Matthew J.)
Published: April 2021

The late fifteenth and early sixteenth centuries were a time of growing affective piety and engagement with the material culture of Christian devotion in Northern Europe. The three so-called lower senses of smell, touch, and taste were very much a part of this devotional context, formed over centuries to be associated with particular fragrances, embraces, and savors. This work argues that artists and patrons exploited a play on these lower senses as integral parts of the composition, utilizing objects, actions, and even persons to trigger sense memory, ideas, and appropriate practice in viewers. The Epiphany, or the biblical event when magi from the east brought gifts of gold, frankincense, and myrrh to the newborn Jesus, was a popular subject for altarpiece paintings. It was one of three most popular altarpiece subjects in the late medieval Low Countries. Its association with the Eucharist and the phenomenon of infrequent communion for the laity at the time helps to explain why the lower senses became important in these works. Smell is highly associated with memory and was stimulated in these altarpieces to reinforce positive life events with the Church's worship. Touch and taste are braided senses that imply contact with Christ through the Eucharist, if only visually. Marginal persons also appear in these paintings becoming living symbols of the senses that help to correct over-enthusiasm for miraculous and direct contact with the holy.
The nonprofit incorporation of America, 1860-1932
Authors:   , Gallagher Kory Paul
Published: April 2021

This project is an examination of the formation of corporatized charitable organizations from 1860-1932. Focusing on six organizations--the United States Sanitary Commission, the Freedmen's Bureau, the Peabody Foundation, the Slater Fund, the American National Red Cross, and the Young Men's Christian Association--it encourages scholars to view large-scale charities as more than good works, instead acknowledging the inherently corporate nature of nonprofit corporations. This study makes three arguments. First, the experience of the Civil War produced two possible paths to a modern civil society, with the model of independent organizations winning out over direct government intervention. Second, into the void left by the federal government's exit came private foundations, which desired to operate in a corporate manner, while expecting a corporate culture among those receiving their funds. This led to the corporatization of organizations that sought legitimacy in the eyes of major donors. Third, with organizations becoming corporatized, they were welcomed into the government-big business-association alliance that became the basis for governing in lieu of direct federal intervention. A system which was exposed as not up to the task presented by the Great Depression as it failed to respond appropriately to a drought in Arkansas in 1932.
Critical information consumption and textbooks used in teacher preparation programs
Authors:   , Smith-Nelson Courtney K.
Published: April 2021

Critical information literacy (CIL) and critical information consumption (CIC) are essential skills and habits of minds for pre-service teachers to develop as they prepare to educate future generations. The purpose of this critical discourse analysis was to investigate ways in which introductory teaching or pedagogy textbooks used in public universities' teacher preparation programs facilitate (or decline to facilitate) the direct and indirect application of CIL/CIC skills. Specifically, textbooks were evaluated on their (1) direct and indirect philosophical and epistemological discussion; (2) direct discussion of evaluating sources of information; (3) attention to power dynamics, biases, ideologies, and underlying assumptions in media and scholarly work; and (4) use of buzzwords and/or epistemically suspect statements. Findings were based on inductive analysis of emergent themes and suggest that there are key features of a text that indicate how CIL/CIC-favorable a work may be. These features include questioning, linguistic granularity, presenting strengths and criticisms of prominent paradigms, attending to power asymmetries in the classroom, and making explicit the hidden or implied messages in educational settings.
HEALTH AND BENEFITS OF LUFFA ACUTANGULA (RICHGUARD)
Authors: Galave Vishal , Hingase Nikita , Bhagat Snehal , Ghone Priyanka , Kashid Pooja , Mandhare Trushali
Published: April 2021

Luffa acutangula (Cucurbitaceae), an enduring plant fills primarily in India, Southeast Asia, China, Japan, Egypt, and different pieces of Africa, it is generally utilized in the customary Indian restorative framework to treat different ailments. The plant has been utilized in jaundice, diabetes, hemorrhoids, diarrhea, cerebral pain, ringworm disease, and uncleanliness. In excess of 50 substance compounds have been disengaged from a plant which chiefly includes flavonoids, anthraquinones, proteins, unsaturated fats, sapon in triterpene, unstable parts, and other phytoconstituents. Unrefined concentrate of plant and its secluded mixtures have expansive pharmacological exercises like antidiabetic, hepatoprotective, antiulcer, anticancer, immunomodulatory, antihyperlipidemic, cell reinforcement, antimicrobial, CNS depressant, pain relieving, and calming. The toxicological assessment in preclinical investigations detailed wellbeing of the plant for human utilization, yet thorough assessment in clinical examinations is required. Notwithstanding, further examination is important for change of involvement based treatment of plant into proof based data. Assessment of pharmacological movement with characteristic biomarkers will assist with uncovering the instrument of activity of compound constituents of plant remove. The information from preclinical investigations suggests clinical assessment of security and viability of the plant. The current paper sums up forward-thinking data about a survey of the customary uses, phytochemistry, pharmacological exercises, and toxicology to feature the future possibilities of the plant.
Había una vez una tortuga y un lobo
Authors: Reyes Carlos
Published: April 2021

â€”
La tortuga diferente
Authors: Ponce Claudia Martinez , Maldonado Yolanda
Published: April 2021

â€”
Los dos hermanos y el salmón más grande
Authors: Naranjo Yulissa
Published: April 2021

â€”
RANCANG BANGUN MESIN PEMOTONG KENTANG BERBENTUK STICK
Authors: Saparin Saparin , Setiawan Yudi , Irwan Edi , Wijianti Eka Sari
Published: April 2021

Penelitian ini merupakan rancang bangun mesin pemotong kentang. Tujuan akhir dari pembuatan mesin adalah produksi kentang berbentuk dadu. Dalam perencanaan mesin akan diproses untuk menghasilkan potongan kentang berbentuk stick. Desain mesin dibuat dengan dimensi 660 mm x 800 mm x 710 mm menggunakan motor listrik ½ Hp. Sistem penurunan putaran menggunakan pulley dan belt 1:2 dan diteruskan gearbox dengan rasio 1:40, cara kerja mesin adalah memutar poros engkol untuk menggerakan piston/penekan kentang dengan putaran 17,5 rpm. Penelitian dilakukan 3 kali dengan 1000 gram kentang dengan rata-rata hasil terpotong baik sebanyak 702 gram, tidak berhasil 27 gram, tertinggal 271 gram. Kapasitas produksi mesin pemotong kentang berbentuk stick ini mampu memotong sebanyak 20,29 kg/jam dengan efisiensi produksi mesin sebesar 70,02%.
Uncommon Ossicle in Holothuria (Mertensiothuria) Leucospilota from Teluk Nipah, Pangkor Island
Authors: Kamarudin Kamarul Rahim , Muhd Lutfi Fatin Najihah , Che Zahri Mohd Zulhafiz , Mohamed Rehan Maryam
Published: April 2021

The high popularity of a commercial sea cucumber species on Pangkor Island (i.e. Stichopus horrens) has resulted in a lack of studies on Holothuria (Mertensiothuria) leucospilota from Pangkor Island, Perak, Malaysia. S. horrens is the main ingredient of gamat-based traditional medicine on the resort island, while H. leucospilota is the most dominant species. For that reason, this study aimed to isolate ossicles from a specimen of morphospecies H. leucospilota collected from Teluk Nipah Beach, Pangkor Island; and to determine the shapes of the ossicles for species verification. A number of six ossicle shapes were observed. Beside buttons and tables as the common ossicle shapes; I-shaped rod, long I-shaped rod, branched rod, and spider-shaped rod were also documented. Nonetheless, the spider-shaped rod is an unusual ossicle shape in H. leucospilota as there was no previous record on it, thus it could be considered as a new finding. In summary, the results of this research indicate the uniqueness of the specimen of morphospecies H. leucospilota as a result of the presence of the spider-shaped rod. More studies with more samples, more morphological approaches as well as more molecular techniques need to be incorporated in future for a better insight.
Influence of Cerium on the Reduction Behaviour of Iron Oxide by Using Carbon Monoxide: TPR and Kinetic Studies
Authors: Tengku Saharuddin Tengku Shafazila , Nor Azman Nurul Syahira Ezzaty , Salleh Fairous , Samsuri Alinda , Othaman Rizafizah , Kassim Mohammad , Mohamed Hisham Mohamed Wahab , Yarmo Mohd Ambar
Published: April 2021

Reduction of iron oxide is one of the most studied topics owing to the importance of iron/steel industry and also has been used as a precursor and active component in a number of important chemical processes. The interaction between iron oxide and other metal additive have gained interest in the past two decades due to the ability on enhancing the reduction performance of the iron oxide. Therefore, this study was undertaken to investigate the influence of cerium on the reduction behaviours of iron oxide by (10%, v/v) carbon monoxide in nitrogen. The cerium doped (Ce-Fe2O3) and non-doped iron oxide reduction behaviour and the kinetic studies have been studied by temperature programmed reduction (TPR) and the phases formed of partially and completely reduced samples were characterized by X-ray diffraction spectroscopy (XRD) while the activation energy values were calculated from Arrhenius equation using Wimmer’s method. TPR results indicate that the reduction of doped and undoped iron oxide proceeds in three steps reduction (Fe2O3 ? Fe3O4 ? FeO ? Fe), while doped iron oxide showed a large shifted towards lower temperature especially in the transition steps of FeO ? Fe. Furthermore, TPR results also suggested that by adding Ce metal into iron oxide the reduction of metal iron completed at lower temperature (700 ?C) compared to non-doped iron oxide (900 ?C). Meanwhile, XRD analysis indicated that doped iron oxide composed of Fe2O3 and a small amount of FeCe2O4. The increase in the rates of iron oxide reduction may relate to the presence of cerium species in the formed of FeCe2O4 and was confirmed by the decrease in the activation energy regarding to all transition phases (Fe2O3 ? Fe3O4 ? FeO ? Fe) during the reduction process
A Study of Object Transparency Via Charge-Coupled Device Mathematical Modelling Assessment
Authors: Raisin Syarfa Najihah , Jamaludin Juliza , Ismail Irneza , Balakrishnan Sharma Rao , Sahrim Mus’ab , Naeem Bushra , Jamal Mohamad Farah Aina , Mohd Zain Ahmad Syahmi , Mohd Fauzi Abdullah Solihin
Published: April 2021

This research discusses an application of Couple-Charge Device (CCD) linear sensor and laser diode in an optical tomography (OPT) system. Tomography is a system that could capture a cross-sectional image based on sensor data scattered across the periphery of the examining device in the non-invasive and non-intrusive framework. This project focuses on quantifying the level of object transparency based on CCD and mathematical modelling assessment. The objective of this project is to investigate the light refraction, reflection and absorption effect on object transparency. The study will include a discussion on the light parameters and its mathematical expression. The voltage output measured by CCD defines the degree of intensity of light obtained after penetrating through different object transparency. In conclusion, this research has successfully proved the potential of CCD in OPT configuration to detect different size diameters of a targeted transparent object, which is an air bubble in non-flowing crystal-clear liquid.
水利工程中水闸施工的技术要点与其注意事项
Authors: 张 鑫磊
Published: April 2021

水利工程的重要性不言而喻，不只是影响人们的生活，同样还关系着经济的发展以及生态的平衡。对于整个水利工程来说水闸是一个比较关键的结构，主要是体现在对于水位的控制上，由此能够在防洪、灌溉以及航运等方面发挥作用。水闸项目包括多个部分，主要的就是闸室以及上下游的连接段，施工是很复杂的，影响因素也很多，因此，应该对这方面进行深入的研究，要明确施工的重点以及要点，然后通过科学的方法、有效的措施切实的提升水闸施工的质量。
对藏区五小水利工程建设的思考
Authors: 兰 军勇
Published: April 2021

建设小型农田水利工程是实践科学发展观，促进新农村建设和农业现代化，保障国家粮食安全的一项重要举措，是一项惠及千万农民的“民心工程”和“德政工程”，是贯彻落实2011年中央1号文件精神的具体措施，社会效益十分显著。
Potential Strategies to Improve Antimicrobial Utilisation in Hospitals in Bangladesh Building on Experiences Across Developing Countries
Authors: Haque Mainul , Godman Brian
Published: April 2021

Abstract not available

Bangladesh Journal of Medical Science Vol.20(3) 2021 p.469-477
Barriers and promotors in receptivity and utilization of feedback in a pre-clinical simulation based clinical training setting
Authors: Abraham Reina M , Singaram Veena S
Published: April 2021

Objective: Many studies have explored feedback effectiveness using interventions focused on feedback delivery. It is equally important to consider how learners actively receive, engage with and interpret feedback. This study explores how medical students receive and use feedback in pre-clinical skills training.

Method: Focus group data from 25 purposively selected thirdyear medical students was thematically analysed. Four major themes and eight sub-themes related to the facilitators and barriers to feedback receptivity and utilisation to feed forward emerged from the data.

Results and Discussion: Students were receptive to feedback when its purpose and content aligned with their personal objectives, when it was consistent between tutors, and when it involved developing longitudinal relationships. The clinical skills formative logbook feedback culture with a learning focus was perceived to be predictive of their future performance and they were likely to take feedback on board, emphasising the role of reflection in this process. The depth and timing of actual feedback use varied among students, and language barriers hindered decoding feedback. Students’ self-regulatory focus on the feedback process had a dominant influence on their active use of feedback.

Conclusion: Incorporating learner behaviour underlying feedback use should be considered when designing interventions to promote feedback engagement, feedback literacy skills and responsibility sharing in the feedback process. Establishing a learning culture that promotes shared responsibility between clinical educators and learners enable greater control by learners over assessment and feedback processes and a commitment to behaviour change.

Bangladesh Journal of Medical Science Vol.20(3) 2021 p.594-607
Characterization of β-Globin Gene Cluster Deletions Using Multiplex-Gap Polymerase Chain Reaction (PCR) and Multiplex Ligation-Dependent Probe Amplification (MLPA)
Authors: Mohamad Redzuwan Yasmin n , Ghani Siti Nor Assyuhada Mat , Ghani Rozanah Abdul , Mohammad Abu Za’ror Yousef Saeed , Bahar Rosnah , Azlan Maryam , Zulkafli Zefarina , Mohamed Saleh Rozieyati
Published: April 2021

Background : Deletions in the β-globin gene cluster are usually rare, problematic to detect, and subsequently possess a challenge in many diagnostic laboratories. They are normally related to the heterozygous of the delta beta (δβ) thalassemia, hereditary persistence of fetalhemoglobin (HPFH) and some of the hemoglobin variants. These disorders are typically presented by elevated levels of hemoglobin F (Hb F), but with low to normal hemoglobin A2 (Hb A2). However, despite their existence, there is still a limited number of studies focusing on this area, hence no definitive diagnosis could be conclusively established. Therefore, this pilot study was carried out to fill this knowledge gap.

Methods: In this study, screening of the selected deletional mutations in the β-globin gene cluster among patients with Hb F (>1%) and Hb A2 (<4%) were performed using multiplex Gap-PCR and multiplex ligation-dependent probe amplification (MLPA).

Results: The results showed that out of 54 samples tested using multiplex Gap-PCR against four target deletions; Thai (δβ)°-thalassemia, HPFH-6, Siriraj J and HbLepore, one sample was found positive with Thai (δβ)°-thalassemia. Further findings from the MLPA screening on 12 randomly selected samples revealed that another patient was positive with double deletions within the region of the β-globin gene cluster. These deletions occur at the gamma-globin gene 1 (HBG1) and gamma-globin gene 2 (HBG2) in exon 3.

Conclusions: In conclusion, this study highlighted the importance of these deletions’ characterization using multiplex Gap-PCR and MLPA which helps in establishing a definitive diagnosis among this selected group of patients.

Bangladesh Journal of Medical Science Vol.20(3) 2021 p.618-624
Acute paroxysmal cold haemoglobinuria; a case report and literature review
Authors: Gajaweera Hasitha , Dayasiri Kavinda , Suraweera Nayani , Gamage Chandrachapa , Weerasekara Kumudu
Published: April 2021

Paroxysmal cold hemoglobinuria (PCH) is a very rare subtype of autoimmune hemolytic anemia caused by the presence of cold-reacting autoantibodies in the blood and characterized by the sudden presence of hemoglobinuria, typically after exposure to cold temperatures. The acute onset PCH occurs following viral illnesses whilst the chronic form is secondary to hematological malignancies and tertiary syphilis. It is a complement mediated intravascular hemolytic anemia associated with a biphasic antibody against the P antigen on red cells. We describe a three year child who had acute onset PCH following likely viral infection. The diagnosis was confirmed by demonstration of strongly positive Donnath Landsteiner antibodies. She made a gradual recovery with supportive treatment, ten days following the initial detection of haemolysis. Parents were educated about the need to avoid cold exposure to prevent precipitation of further haemolysis and folic acid was commenced to assist the recovery of erythropoiesis.

Bangladesh Journal of Medical Science Vol.20(3) 2021 p.654-657
Struktur Kepemilikan Terhadap Pengungkapan Akuntansi Sumber Daya Manusia
Authors: Widodo Nova Maulud , Widagdo Ari Kuncara
Published: April 2021

Abstractâ€” This study aims to analyze and test the ownership structure influence on the human resource accounting disclosure (HRAD). This study empirically examine the influence of ownership structure that is foreign ownership and family ownership on the HRAD. Control variables on this study are firm SIZE, CAR, LDR, and AGE. This study used secondary data obtained through the Indonesia Stock Exchange. HRAD is measured using an index Mamun. The sample was banking companies listed on the Indonesian Stock Exchange 2011-2014 period selected through purposive sampling method. Total annual reports used for analysis were 133 reports. Methods of data analysis in the study using multiple linear regression with SPSS software. The structure of ownership in this study by considering authenticity. In this study, foreign ownership and family ownership is measured by two measurements. The measurement foreign ownership results showed no influence on the HRAD. Family ownership using the first measurement has no influence on HRAD, while using the second measurement significant negative influence. Control variables in this study is the company SIZE and AGE and have positive influence on the HRAD. While the CAR and LDR have negative inluence onÂ  the HRAD.Â Keywordsâ€”: human resource accounting disclosure; ownership structure; banking company.
O impacto da Síndrome de Burnout em enfermeiros do setor de urgência e emergência: Uma revisão integrativa da literatura
Authors: Lima Dhayanna Cardoso , Melo Ianny Caroline Mota de , Costa Clerveson Lima da , Carvalho Marcílio da Costa
Published: April 2021

Objetivo: Discorrer sobre o impacto da Síndrome de Burnout em enfermeiros do setor de urgência e emergência. Metodologia: Trata-se de uma revisão integrativa da literatura, seguindo seis etapas: formação da hipótese ou indagação da pesquisa; amostragem ou busca na literatura; coleta de dados; análise dos estudos incluídos na revisão; interpretação e discussão dos resultados; apresentação da revisão integrativa. Resultados: Os 14 artigos considerados para este estudo foram descritos na tabela, contendo identificação os seguintes itens: título, autor / ano, base de dados, metodologia e resultados. Os resultados identificaram os principais sinais e sintomas de Burnout que acometem o profissional de enfermagem, bem como os fatores que causam impacto na qualidade de vida, e as características do setor de urgência e emergência que influenciam no desencadeamento da síndrome de Burnout. Conclusão: Conclui-se que, o setor de urgência e de um hospital é um local propicio as doenças psicossomáticas aos profissionais que trabalham neste ambiente.
Adaptation of the heart to hypertension is associated with maladaptive gap junction connexin-43 remodeling
Authors: Fialová M , Dlugošová K , Okruhlicová L , Kristek F , Manoach M , Tribulová N
Published: April 2021

We hypothesized that hypertension-related myocardial
remodeling characterized by hypertrophy and fibrosis might be
accompanied by cell-to-cell gap junction alterations that may
account for increased arrhythmogenesis. Intercellular junctions
and expression of gap junction protein connexin-43 were
analyzed in rat heart tissues from both spontaneous (SHR) and
L-NAME model of hypertension. Isolated heart preparation was
used to examine susceptibility of the heart to lethal ventricular
fibrillation induced by low potassium perfusion. Ultrastructure
observation revealed enhanced neoformation of side-to-side type
while internalization of end-to-end type (intercalated disc-related)
of gap junctions prevailed in the myocardium of rats suffering
from either spontaneous or L-NAME-induced hypertension. In
parallel, immunolabeling showed increased number of connexin43 positive gap junctions in lateral cell membrane surfaces,
particularly in SHR. Besides, focal loss of immunopositive signal
was observed more frequently in hearts of rats treated with
L-NAME. There was a significantly higher incidence of
hypokalemia-induced ventricular fibrillation in hypertensive
compared to normotensive rat hearts. We conclude that
adaptation of the heart to hypertension-induced mechanical
overload results in maladaptive gap junction remodeling that
consequently promotes development of fatal arrhythmias.
Research of the adsorption of a methylene blue enterosorbents of various nature
Authors: Лишай Анастасия Викторовна , Савицкая Татьяна Александровна , Цыганкова Надежда Георгиевна , Гриншпан Дмитрий Давидович , Чен Джун
Published: April 2021

The results of the adsorption study of methylene blue dye as the low molecular weight toxins marker from its aqueous solutions by carbon, silicon and polymer enterosorbents are presented. It has been shown that the activated carbons modification by water-soluble cellulose polyelectrolyte makes it possible to increase their adsorption capacity. The applicability of Langmuir, Freundlich, Temkin and Redlich – Peterson adsorption models for the approximation of experimental adsorption isotherms of methylene blue on the enterosorbents has been estimated. It has been established that the three-parameter Redlich – Peterson equation describes this process better than others. This was evident from the comparison of the regression coefficients, constants and parameters values of these equations.
Cellular mechanisms of impaired mineralocorticoid and glucocorticoid production by endocrine disruptor DDT
Authors: Yaglova Nataliya V. , Obernikhin Sergey S. , Yaglov Valentin V. , Nazimova Svetlana V. , Timokhina Ekaterina P.
Published: April 2021

Developmental exposure to persistent endocrine disruptors is of a great concern. Affection of adrenal hormones production by low-dose exposure to dichlorodiphenyltrichloroethane (DDT) has been revealed recently. Objective of the research – investigation of ultrastructural mechanisms of impaired mineralocorticoid and glucocorticoid production after prenatal and postnatal exposure to endocrine disruptor DDT. Male Wistar rats exposed to low doses of DDT during prenatal and postnatal development were studied. Aldosterone and corticosterone levels in serum were measured by enzyme-linked immunosorbent assay, histological examination and electron microscopy of the adrenals were performed. Pubertal rats, developmentally exposed to low doses of DDT, demonstrated lowered aldosterone and elevated corticosterone serum levels. After puberty the rats showed tendency to normalization of hormones’ production. Morphological examination of the adrenals revealed less developed zona glomerulosa in pubertal period and its relative hyperplasia after puberty. Microcirculatory disorders and focal cell death were observed in outer zona fasciculata. Electron microscopy of glomerulosa cells found signs of suppressed secretory activity in pubertal period and no significant reduction of mitochondria size in adult rats. Total number of mitochondria in 1 µm2 of cytoplasm and percent of mitochondria with swollen matrix were diminished compared to the control. Cells of inner zona fasciculata demonstrated increased functional activity. Age-dependent changes in fine structure of fasciculata cells were similar to the control, but were more pronounced. In this way, cellular mechanism of impaired mineralocorticoid production in rats prenatally and postnatally exposed to low doses of endocrine disruptor DDT, are insufficient mitochondrion function and impaired reorganization of mitochondrial apparatus, which occurs during pubertal period. Mechanisms of elevated glucocorticoid secretion are attributed to enhanced function of mitochondria in fasciculata cells.
DEVELOPMENT OF CORPORATE MARKETING COMMUNICATION (CMC) BRANDING MODEL IN IAIN TULUNGAGUNG: TOWARD THE ERA OF WORLD CLASS UNIVERSITY
Authors: Purwowidodo Agus , Yasin Muhamad
Published: April 2021

The study describes and analyzes the use of corporate marketing communication strategies towards Higher Education at the international level. This study used a qualitative descriptive method, with the research site at IAIN Tulungagung. The research subjects are members of the academic community, teaching staff, education staff and stakeholders. The research period was for the 2018/2019 academic year. The results showed that the typology of the marketing or promotion model used collaboration between internal parties (academics, stakeholders) and external parties (institutions, channel partners, media, government, industrial bodies and institutions, the educational community and the general public). Its implementation uses corporate advertising, sponsorship, sales presentations, online activities, branding, corporate advertising, press releases, press conferences, events, and awards. The study implications deal with the increase in: (1) Higher Education Identity, Image, Reputation; (2) Higher Education Social Responsibility (CSR); (3) media relation effectiveness; (4) more efficient marketing communications; (5) the more intensive Internal Communication System; (6) investor relation improvement; (7) conducive relations with the Government, and (8) the reliability in overcoming crisis communication. These have an impact on improving the quality of IAIN Tulungagung toward the level of International Higher Education.
The 2019 Afghan Presidential Election: An Assessment of Problematic Processes and Results
Authors: Johnson Thomas
Published: April 2021

This article assesses Afghanistan's Presidential Election of 2019. Analyzing official data from the Afghan Independent Election Commission (IEC), it examines voting patterns at both the national and provincial levels and compares these results with those of past elections. It draws on statistical methods to evaluate Afghan electoral procedures, focusing in particular on the practice of ballot invalidation and voter suppression as well as the role of ethno-linguistic voting blocs. The analysis reveals highly unusual voting patterns and other dynamics that point to significant irregularities and fraud. The article concludes with a number of recommendations for future Afghan elections.
Granting Business License to Fuel Traders “Pertamini” As a Form of Legal Protection
Authors: Junus Nirwan , Mamu Karlin Zakaria , Aditya Cono Mohamad Syahnez W.
Published: April 2021

Oil and Gas plays an important role in the fulfillment of fuel needs from both the industrial and transportation sectors. This regulation on Oil and Gas has provided a legal basis in its implementation.  The presence of retail fuel businesses "Pertamini" is causing legal problems, this is because the existence of these businesses do not have a formal business license at all.This paper analyzes the sale of fuel under the brand "Pertamini" which does not have a business license. This research uses normative legal research method with statute approach and conseptual approach.The results showed that, with the increasing number of "Pertamini" fuel traders without a license, it will certainly have implications for the law and uncontrolled management of Oil and Gas. Therefore, the government and related agencies can issue permits to "Pertamini" fuel traders. Because by obtaining a legal business license, in terms of its management can be carried out optimal supervision to prevent the occurrence of fuel misuse. This also includes efforts to provide certainty and legal protection to "Pertamini" Fuel Traders.
Нові дані до хронології стратифікованого поселення Сабатинівка І
Authors: Kiosak Dmytro , Siekerska Olena
Published: April 2021

У роботі публікуються чотири нові радіовуглецеві визначення, які спрямовані на вирішення актуальної проблеми абсолютної хронології двох шарів Сабатинівського поселення – нижнього (Трипілля В1) та верхнього (доба пізньої бронзи). Одержані дані свідчать на користь існування нижнього шару у межах XLIV-XLII ст. до н.е., а верхнього – XVI-XV ст. до н.е.
Один тип кістяних артефактів з Ольвії та його інтерпретація
Authors: Semenova Alisa
Published: April 2021

У статті розглядається одна з найчисельніших категорій кістяних артефактів з Ольвії – модифікованих довгих кісток великих свійських тварин з рядами насічок на робочій поверхні. Довгий час їх помилково вважали знаряддями для обробки кераміки, кістки, вичинки шкур і навіть шліфування каменю. Справжнє ж їх призначення, як підставок-наковань для нанесення зубців на гофрований серп, вдалося встановити за допомогою численних даних етнографії.
Особливості благодійництва в Ольвійському полісі (VI-I ст. до н.е.)
Authors: Ruchynska Oksana
Published: April 2021

У статті надається аналіз благодійницької діяльності в Ольвійському полісі, притаманної як громадянам Ольвії, так і іноземцям. На основі епіграфічних джерел висвітлюються характерні риси благодійництва з моменту заснування поліса та до кінця елліністичного періоду. Стверджується, що благодійницька практика Ольвійської еліти була близька до евергетизму, в елліністичний період вона відображала соціальну гідність й оціночні орієнтири громадянського колективу.
Походи русів у Табарістан у другій половині ІХ – на початку Х століть: маршрут і місце у міжнародних відносинах (за матеріалами Ібн Ісфандійара)
Authors: Kuzovkov Volodymyr
Published: April 2021

У статті досліджуються дискусійні питання стосовно обставин перших походів русів на Каспій (між 864-883, 909/910 і 910/911), відомих за свідченнями ібн Ісфандійара, Амулі та Мар’аши. Окрема увага приділяється місцю цих військових акцій у русько-хазарських відносинах, їх впливу на міжнародні відносини у регіоні навколо Каспійського моря. Автор розглядає шляхи, якими руси потрапляли до мусульманського світу, і пропонує власну версію маршруту руських контингентів. Відмічається зв’язок розглянутих походів з військовою акцією русів, що відбулась між 913 і 917 рр., відомою за описом аль-Масуді.
Археологічна діяльність Анатолія Віссаріоновича Буракова у 1950-1960-і рр. (розкопки поселення ольвійської периферії біля c. Козирка)
Authors: Shevchenko Tetiana
Published: April 2021

У статті висвітлено археологічну діяльність Анатолія Віссаріоновича Буракова у 1950-1960-і рр., зокрема, розкопки поселення ольвійської периферії біля с. Козирка. Роботи переслідували декілька цілей – шляхом розвідки з’ясувати основні культурно-хронологічні нашарування городища та встановити стан збереження археологічних об’єктів, визначити їх перспективність з точки зору подальших наукових розкопок. Під час досліджень були відкриті оборонні і житлові споруди, значний керамічний комплекс, предмети побуту, аналогії яким знайдено серед пам’яток провінційно-римської культури.
The Thermodynamics of Medial Vascular Calcification
Authors: Millán Ángel , Lanzer Peter , Sorribas Víctor
Published: April 2021

Medial vascular calcification (MVC) is a degenerative process that involves the deposition of calcium in the arteries, with a high prevalence in chronic kidney disease (CKD), diabetes, and aging. Calcification is the process of precipitation largely of calcium phosphate, governed by the laws of thermodynamics that should be acknowledged in studies of this disease. Amorphous calcium phosphate (ACP) is the key constituent of early calcifications, mainly composed of Ca2+and PO43–ions, which over time transform into hydroxyapatite (HAP) crystals. The supersaturation of ACP related to Ca2+and PO43–activities establishes the risk of MVC, which can be modulated by the presence of promoter and inhibitor biomolecules. According to the thermodynamic parameters, the process of MVC implies: (i) an increase in Ca2+and PO43–activities (rather than concentrations) exceeding the solubility product at the precipitating sites in the media; (ii) focally impaired equilibrium between promoter and inhibitor biomolecules; and (iii) the progression of HAP crystallization associated with nominal irreversibility of the process, even when the levels of Ca2+and PO43–ions return to normal. Thus, physical-chemical processes in the media are fundamental to understanding MVC and represent the most critical factor for treatments’ considerations. Any pathogenetical proposal must therefore comply with the laws of thermodynamics and their expression within the medial layer.
Insight Into Chromatin-Enriched RNA: A Key Chromatin Regulator in Tumors
Authors: Zhang Jixing , Ding Tianyi , Zhang He
Published: April 2021

Chromatin-enriched RNAs (cheRNAs) constitute a special class of long noncoding RNAs (lncRNAs) that are enriched around chromatin and function to activate neighboring or distal gene transcription. Recent studies have shown that cheRNAs affect chromatin structure and gene expression by recruiting chromatin modifiers or acting as bridges between distal enhancers and promoters. The abnormal transcription of cheRNAs plays an important role in the occurrence of many diseases, particularly tumors. The critical effect of cancer stem cells (CSCs) on the formation and development of tumors is well known, but the function of cheRNAs in tumorigenesis, especially in CSC proliferation and stemness maintenance, is not yet fully understood. This review focuses on the mechanisms of cheRNAs in epigenetic regulation and chromatin conformation and discusses the way cheRNAs function in CSCs to deepen the understanding of tumorigenesis and provide novel insight to advance tumor-targeting therapy.