bluuebunny/crossref_metadata_2025 huggingface dataset:
Development Of Pop Up Book To Increase Interest and Learning Outcomes
Authors: Komari Muh. , Widiyaningrum Priyantini , Partaya Partaya
Published: March 2024

The learning of integrated science should be supported by several things including the existence of Learning Media. The reality is that at MTs Putera Sunniyyah Selo, there are not many interesting learning media found. Even though the learning media is very important for the realization of student interest and learning outcomes. Therefore, it is necessary to develop Pop Up Book as a Learning Media. The purpose of this research is to develop Pop Up Book as learning media material on the interaction of living things with the environment, its validity and effectiveness as a learning media, and to find out how much student interest in using of Pop Up Books as a learning media. The method of research is use Research and Development (R&D). The validity test was carried out by media experts and material experts using a questionnaire. The effectiveness of learning media was measured based on the N-Gain value indicator from the pretest-posttest results, as well as the teacher and student response questionnaire scores. Student learning interest is measured based on the questionnaire score of student learning interest. The test of the effectiveness of learning media was carried out at MTs Putera Sunniyyah Selo, Tawangharjo District, Grobogan Regency, in grade VII. The results showed that the validation score of the media expert reached 88.19%, while the validation score of the material expert validation reached 90.69% with an average of 89.44%, which means that the learning media could be elassified valid. The results of the analysis of the effectiveness of the media based on the N-Gain value were 0.8, which means that the increase in the pretest posttest could be classified as high criteria. The scores for the questionnaire responses from teachers and students were 92.50% and 86.46%, both of which were very effective. The percentage of interest in learning reached 90.09% with very good criteria. Based on these indicators, it can be concluded that the Pop Up Book as a Learning Media is declared valid by media and material experts, is effectively used in learning and is able to generate interest in learning at MTs Putera Sunniyyah Selo in the very good category.
Effectiveness of E-Supplement Mobile Android Application toward Science Literacy Skills on Minimum Competency Assessment Oriented in Respiratory System of Junior High School Students
Authors: Alfan Dheny Choirul , Saptono Sigit , Lisdiana Lisdiana
Published: March 2024

Learning on 21st century is supported by sophisticated technology, where the demands on situations and conditions require people to be able in adjusting all experiences possessed to solve problems scientifically in everyday life. Students' analytical skills and scientific thinking in daily life become one of the important aspects that support the achievement of educational goals. This research aims to analyze the science literacy skills of students grade 8 at State Junior High School 2 Tulung, Klaten while learning Respiration System applied by E-Supplement Mobile Android on Minimum Competency Assessment-Oriented. This study used method of Research and Development for 102 students of respondents from 4 classes. The research is designed by ADDIE. The results of the pot-test scores were higher than the pre-test scores with an average of 82.74% with classical completeness of 81.37% and the N-Gain test results of 56% in the high category. In addition, the application of the e-supplement mobile android application effectively improves students’ scientific literacy skills in terms of knowledge and competence.
Development of STEAM-Based Human Respiratory System Teaching Materials to Improve Students' Critical Thinking Skills
Authors: Wafi Mumtaz Al , Lisdiana Lisdiana , Sumarti Sri Susilogati
Published: March 2024

This study aims to examine the validity of teaching materials and the effectiveness of STEAM-based human respiratory system teaching materials in improving students' critical thinking skills. The type of research used is research and development (R&D) which uses the ADDIE development model with a trial design of teaching materials using One Group Pretest-Posttest Design. The research subjects consisted of two material expert validators, one media expert validator, 7 subject teachers, and 143 class VIII junior high school students in Comal Pemalang Regency. The research instruments were in the form of needs analysis sheets, teaching materials validation sheets, and assessment instruments. The results of the validity of teaching materials by material and media experts obtained a very valid category. The results of the N-Gain analysis on the critical thinking indicator obtained a value of 0.68 in the medium category. STEAM-based human respiratory system teaching materials are feasible to use in learning and effective in improving students' critical thinking skills.
The Analysis of Biology Learning Assesment Implementation in Jepara High School During Covid-19 Pandemic
Authors: Rohman Alif Khoirur , Widiyaningrum Priyantini , WH Nugrahaningsih
Published: March 2024

The Covid-19 pandemic has changed education that was previously conducted face-to-face to online learning. However, it is still necessary to conduct a learning assessment to determine student learning achievement. This study aims to describe the application of assessment in Biology learning in 3 public high schools in Jepara Regency. This research is a descriptive research with a qualitative approach. Data were taken by means of document analysis, observation and interviews. Data were analyzed using the Milles & Huberman model which consisted of data reduction, data presentation and conclusion drawing. The results of this study indicate that the biology teachers of SMAN 1 Mayong, SMAN 1 Pecangaan and SMAN 1 Welahan have compiled a complete lesson plan and online learning assessment instrument. Assessment techniques used in online learning vary from multiple choice, essay questions, simple practicum, independent projects and portfolios. While the online assessment applications used by teachers include google form, quizizz, google classroom, microsoft teams. The teacher begins learning by providing material to be explained to students, but when a more specific explanation is needed, the teacher usually uses the help of a learning video or video conference using the Zoom Meeting application or Google Meet. Cognitive, affective and psychomotor assessments can be carried out by teachers in online learning.
The Effectiveness of "Sipentik" as an Authentic Assessment Application for Increasing Student IT Literacy
Authors: Hidayah Falis Ulil , Linuwih Suharto , Subali Bambang
Published: March 2024

MTs and SMP teachers in Rowosari Kendal District have difficulty carrying out authentic assessments manually because the components being assessed and the number of students to be observed are not small, and it takes a lot of time and effort, and they are prone to errors or omissions in the assessment. In addition, they are aware that the assessment is still focused on the cognitive aspects of students through learning achievement tests, while the assessment of attitudes and skills is only at a glance without using assessment instruments, besides that teachers must address technological developments that are increasingly accelerating and it is important to increase students' IT literacy. One of the potential learning methods to help teachers in authentic assessment and improve IT literacy is by applying the Authentic Assessment System (Sipentik) application.. The purpose of this research is to describe and analyze the characteristics of Sipentik as an authentic assessment application for teachers and the effectiveness of the Sipentik application in the teaching and learning process in schools. This type of field research uses a mixed methods approach with an embedded experimental model design , with data collection techniques through documentation, questionnaires, observations, and interviews. The data that has been collected can then be analyzed through quantitative and qualitative data analysis. The results of the study show that: 1) "Sipentik" as an authentic assessment application for teachers has the characteristics of this internet-based application with its main feature being technology for authentically assessing students, besides that it can also help teachers manage the learning system in class more easily and directed, also makes teachers more able to improve IT literacy. 2) The Sipentik application in the teaching and learning process in schools is effective as an authentic teacher assessment to improve students' IT literacy at SMP N 1 Rowosari, 3) The authentic assessment of SMP N 1 Rowosari teachers using the Sipentik application shows better and more effective than using the manual.
Development of Pteridophyta E-Teaching Materials In The Bantarbolang Natural Reserve Whit A Scientific Approach To Train Critical Thinking Skills
Authors: Bayu Bagus Adi , Rahayuningsih Margareta , Irsadi Andin
Published: March 2024

Bantarbolang Nature Reserve as a conservation area has not been widely recognized, and has not been utilized in learning. Students also need learning that can train critical thinking skills. The aim of the research is to analyze the diversity of pteridophyta in the Bantarbolang Nature Reserve, to analyze the characteristics, validity and effectiveness of the E-peteridophyta teaching materials in training students' thinking skills. This research is Research and Development (R&D) using 4D model swhich includes four stages, that is Define, Design, Develop, and Disseminate. The results of the study showed (1) Diversity of Pteridophyta in the Bantarbolang Nature Reserve, whichfound 14 species of ferns, from 6 different families. The diversity of ecosystems in the Bantarbolang Nature Reserve, there are River Ecosystems, Forests and Teak Forests. (2) The characteristics of the Pteridophyta E-Materials in the Bantarbolang Nature Reserve have advantages, such as providing contextual examples of images, presented by collaborating between scientific approaches and process skills, and displayed in electronic form which makes it easy to use. (3) The validity of the Pteridophyta E-teaching materials in the Bantarbolang Nature Reserve, obtained an assessment score from material experts of 94.38% so that it is included in the very valid category, and an assessment score from media experts of 98.30% so that it is included in the very valid category. (4) The effectiveness of E-teaching materials on students' critical thinking skills obtains an N-gain score of 0.70, which means the high category, and obtained an Effect size score of 0.49, which means the medium category, thus showing effective results on critical thinking skills with the application of E - Teaching materials.
High-intensity interval training combining rowing and cycling improves but does not restore beta-cell function in type 2 diabetes
Authors: Houborg Petersen Maria , Stidsen Jacob Volmer , Eisemann de Almeida Martin , Kleis Wentorf Emil , Jensen Kurt , Ørtenblad Niels , Højlund Kurt
Published: March 2024

Aim

We investigated whether a high-intensity interval training (HIIT) protocol could restore beta-cell function in type 2 diabetes compared with sedentary obese and lean individuals.

Materials and methods

In patients with type 2 diabetes, and age-matched, glucose-tolerant obese and lean controls, we examined the effect of 8 weeks of supervised HIIT combining rowing and cycling on the acute (first-phase) and second-phase insulin responses, beta-cell function adjusted for insulin sensitivity (disposition index), and serum free fatty acid (FFA) levels using the Botnia clamp (1-h IVGTT followed by 3-h hyperinsulinemic–euglycemic clamp).

Results

At baseline, patients with type 2 diabetes had reduced insulin sensitivity (~40%), acute insulin secretion (~13-fold), and disposition index (>35-fold), whereas insulin-suppressed serum FFA was higher (⁓2.5-fold) compared with controls (all P < 0.05). The HIIT protocol increased insulin sensitivity in all groups (all P < 0.01). In patients with type 2 diabetes, this was accompanied by a large (>200%) but variable improvement in the disposition index (P < 0.05). Whereas insulin sensitivity improved to the degree seen in controls at baseline, the disposition index remained markedly lower in patients with type 2 diabetes after HIIT (all P < 0.001). In controls, HIIT increased the disposition index by ~20–30% (all P < 0.05). In all groups, the second-phase insulin responses and insulin-suppressed FFA levels were reduced in response to HIIT (all P < 0.05). No group differences were seen in these HIIT-induced responses.

Conclusion

HIIT combining rowing and cycling induced a large but variable increase in beta-cell function adjusted for insulin sensitivity in type 2 diabetes, but the disposition index remained severely impaired compared to controls, suggesting that this defect is less reversible in response to exercise training than insulin resistance.

Trial registration

ClinicalTrials.gov (NCT03500016).
On approximation of stochastic integral equations driven by continuous p-semimartingales
Authors: Kubilius Kęstutis
Published: March 2024

There is not abstract.
Statistical analysis of congenital anomlies in children in Lithuania
Authors: Radavičius Marijus , Sušinskas Jurgis , Utkus Algirdas
Published: March 2024

Trends, prevalence and some influential (risk) factors of congenital anomlies in children in Lithuania are investigated using logistic regression model.
Смешанные билинейные дискретные решения
Authors: Bistrickas Vilius
Published: March 2024

There is not abstract.
The mathematical modeling of counter-attack
Authors: Pincevičius Albertas , Rakauskas Rimantas-Jonas , Misevičius Gintautas , Vašterienė Svajonė
Published: March 2024

There is not abstract.
On some Features of Funerary Assemblage of the Egyptian Priestess Nesmut
Authors: Tarasenko M. O.
Published: March 2024

The subject of this paper is the analysis of funerary assemblage of Nesmut, the Egyptian priestess of the 21st Dynasty (her titles are “Mistress of the House, Chantress of Amun, king of the gods”). The burial of Nesmut was discovered in 1891 in the so-called “Second Cache” at Deir al-Bahri, also known as Bāb el-Gusūs (set no. A.48). Inventory that was discovered on the mummy: leather mummy braces, three “napkins”, linen gloves, shale heart scarab, and wax images of the sons of Horus. Inventory that was found near or inside of the coffin: two shabti-boxes, shabtis. Nesmut’s mummy cover is located in the Museum of Antiquities in Cairo (Cairo CG 6007). Her coffin is currently stored in the Odesa Archaeological Museum (OAM) of the National Academy of Sciences of Ukraine (inv. no. 71695). It was part of the so-called Lot VI presented to Russian Empire by Egyptian government in 1893. In 1895, the coffin of Nesmut was sent from Odesa to the Archaeological Museum of St. Volodymyr Kyiv University. In 1959 the coffin of Nesmut was among other objects that were transferred from the State Republican Historical Museum in Kyiv to the OAM. The lid of the coffin with inv. no. OAM 71695 differs in design style from the trunk and has an earlier dating. Structurally, the lid has retained traces of technological processing and fitting the trunk of the later coffin of its namesake. Accordingly, there were two Nesmuts, whose funerary objects were discovered in Bāb el-Gusūs. The burial of Nesmut (II) corresponds to the set no. A.48 by Daressy and it is linked with the coffin trunk no. OAM 71695. Separate objects from Nesmut’s (I) grave goods were adapted for later burials: the lid of her inner coffin was used for the Odesa coffin of Nesmut (II), and the lid of the outer coffin might have been adapted for an anonymous burial from Bāb el-Gusūs set no. A.54 (Swiss lot IX, Neuchâtel, Musée d’Ethnographie, inv. no. Eg. 184) on which the name “Nesmut” preserved in one segment of the lid. The burial of Nesmut was also equipped with two different types of shabtis. It is possible that like the lid of the coffin, part of the shabtis was “usurped” by Nesmut (II) and previously belonged to the burial of her namesake and probably relative, Nesmut (I). It is quite probable, that they were reused and adopted for the burial of new owner together with the shabti-box, since the two of them were found in the set no. A.48. This may prove that during the 21st Dynasty, not only large objects, but also small items of grave goods could be reused.
SYNERGISM OF ANTIMICROBIAL ACTIVITY OF ANTIBIOTICS WITH BIOCIDES OF NATURAL ORIGIN
Authors:   National University of Food Technologies, Kyiv, Ukraine, Pirog T.P. ,   Institute of Microbiology and Virology of NASU, Kyiv, Ukraine
Published: March 2024

Currently, antibiotic therapy remains the primary method for treating infectious diseases in humans. Nevertheless, its effectiveness is rapidly decreasing due to the widespread emergence of resistant pathogens, necessitating the exploration of new treatment options. One potential approach involves the use of antibiotics in combination with other natural compounds. Aim of the review was to summarize the literature data on the synergy of the antimicrobial action of combinations of antibiotics with various biocides against Gram-positive and Gram-negative pathogenic microorganisms. The analysis of literature data has shown that promising compounds for use in combinations with antibiotics include essential oils, other plant components, antimicrobial peptides (both natural and synthetic), and microbial surfactants. In the majority of studies, the researchers calculated the fractional inhibitory concentration index, confirming the synergistic antimicrobial activity of antibiotics and the mentioned compounds. The use of natural biocides in combination with commercial antibiotics, particularly against Gram-negative (including methicillin-resistant) Staphylococcus species and Gram-positive microorganisms (Escherichia coli, Pseudomonas aureginosa, Klebsiella pneumoniae, Proteus mirabilis, Acinetobacter baumannii), enabled to consider these mixtures not only as effective antimicrobial agents but as one of the ways to reduce the effective concentration of antibiotics as well. It should be noted that in the presented studies, the researchers only observed the synergy of antimicrobial activity between a combination of antibiotics and other biocides, without emphasizing the potential mechanisms of interaction between the components of the complex. This likely depended on various factors, including the qualitative composition of natural compounds. Therefore, it was important to continue research not only on the synergy of antimicrobial activity in compound mixtures but also on the underlying mechanisms of their interaction. This would provide insights to enhance their effectiveness in combating resistant microorganisms.
A Quality Improvement Initiative to Increase Skin-to-Skin Care Duration in Preterm Neonates
Authors: Balasundaram Palanikumar , Frascone Melissa , Wnukowski Samantha , Murphy Alana G. , Connors Jillian
Published: March 2024

BACKGROUND

Skin-to-skin (STS) care effectively improves neonatal outcomes, particularly for preterm neonates. However, utilization of STS remains suboptimal for the most vulnerable preterm neonates in the first 4 weeks of life. This quality improvement (QI) project aimed to increase STS duration for neonates under 35 weeks gestation.

METHODS

The QI initiative was conducted in a 35-bed level IV NICU within a teaching hospital in New York City from July 2021 to January 2023. Six months of baseline data and a staff survey determined interventions across “Plan, Do, Study, Act” cycles. Interim analyses guided interventions using run charts. Interventions included parental counseling and information leaflets, discussion during rounds on STS eligibility, STS education for residents, nurses’ feedback, and visual reminders. The primary outcome measure was the mean duration of STS per eligible patient day. The process measures were the age at first STS and documentation of eligibility for STS care in the electronic medical records. Balancing measures included adverse events such as apnea, bradycardia, desaturation, hypothermia, and inadvertent dislodgement of central lines and endotracheal tube.

RESULTS

The study included 185 infants with a mean gestational age of 29.1 weeks. The mean STS duration per eligible patient day increased from a baseline of 13.3 minutes to 32.4 minutes without significantly increasing adverse events.

CONCLUSIONS

The QI interventions implemented have successfully increased the duration of STS in preterm infants. Our interventions combined into an STS bundle can be a potential model for other NICUs to improve STS practice.
Acquired Hemophilia: A Rare Complication of Pediatric Idiopathic Multicentric Castleman Disease
Authors: Appell Lauren E. , Mack Joana M. , Farrar Jason E. , Roper Sydney N. , Savage Matthew R. , Pandey Soumya , Crary Shelley E.
Published: March 2024

Acquired hemophilia is caused by acquired autoantibodies to 1 of the factors of the coagulation cascade, usually factor VIII or IX, and is an exceedingly rare phenomenon in children. The finding of an acquired factor VIII inhibitor in a pediatric patient with idiopathic multicentric Castleman disease has never been reported. Patients with acquired hemophilia can have life-threatening bleeds that are refractory to blood product support, requiring bypassing agents to manage bleeding symptoms. We present the novel finding of acquired hemophilia resulting from an autoantibody to factor VIII in a pediatric patient with idiopathic multicentric Castleman disease and discuss the optimal management of bleeding in a patient with acquired hemophilia.
Estudio de la actitud hacia la utilidad de la matemática en estudiantes de precálculo matriculados en el I Cuatrimestre 2022
Authors: Castro Méndez Didier Alberto
Published: March 2024

La investigación en cuestión se enfoca en evaluar la actitud de los estudiantes del curso de precálculo de la ULACIT hacia la utilidad de las matemáticas. La muestra comprendió a 315 estudiantes inscritos en el primer cuatrimestre de 2022, en un entorno de aprendizaje combinado debido a las restricciones impuestas por la pandemia de COVID-19. El objetivo principal de la investigación fue analizar el nivel de actitud hacia la utilidad de las matemáticas en los estudiantes de precálculo en el primer cuatrimestre de 2022 en la ULACIT. Además, se establecieron tres objetivos específicos: investigar si existen diferencias significativas en la actitud hacia las matemáticas según el sexo, el área de estudio y la modalidad educativa de los estudiantes. Los resultados del estudio revelaron que no hay diferencias estadísticamente significativas en la actitud hacia la utilidad de las matemáticas en función del sexo o el área de estudio de los estudiantes. Sin embargo, se encontraron diferencias significativas en relación a la modalidad educativa: los estudiantes que tomaron el curso de forma presencial mostraron una actitud más positiva hacia la utilidad de las matemáticas en comparación con aquellos que optaron por la modalidad virtual.
Chinese Chopsticks
Authors: Kemasang A R T
Published: March 2024

This essay, mostly concerns the history of chopsticks and their use in China with brief observations about the fundamental differences between their use in Japan.
Andrew Dalby and Rachel Dalby: Gifts of the Gods: A History of Food in Greece
Authors: O’Connor Kaori
Published: March 2024

Andrew Dalby and Rachel Dalby: Gifts of the Gods: A History of Food in Greece: Reaktion Books, 2017; 304pp., 123 illustrations, 111 in colour, hardback,. £25.
Nicole Tarulevicz: Eating Her Curries and Kway: A Cultural History of Food in Singapore
Authors: O’Connor Kaori
Published: March 2024

Nicole Tarulevicz: Eating Her Curries and Kway: A Cultural History of Food in Singapore: University of Illinois Press, 2013: 224 pp., hardback with 10 b/w illus., £34.
Educar la humildad durante la adolescencia
Authors: Encío-Avello Alicia , Ahedo-Ruiz Josu , Caro-Samada Carmen
Published: March 2024

El objetivo del presente artículo es plantear sugerencias para educar la virtud de la humildad en la adolescencia. Para ello se analiza la propuesta de June Tangney, quien distingue seis rasgos que hemos agrupado en la dimensión interior, en relación con el autoconocimiento, y la dimensión exterior, referente a la relación con otros y con el universo. Se analizan estos seis elementos proponiendo un orden para una intervención educativa en el aula. Las estrategias educativas señaladas pueden servir de referencia para ayudar en la adquisición de la humildad, lo que implica la mejora de las relaciones interpersonales y el autoconocimiento.
Evaluación del impacto de un programa de formación del potencial emprendedor en estudiantes de educación secundaria
Authors: Azqueta Arantxa , Sanz-Ponce Roberto , Núñez-Canal Margarita , Montoro-Fernández Elisabet
Published: March 2024

Se evalúa el impacto de un programa de formación del potencial emprendedor en el desarrollo de las habilidades empresariales de 1036 estudiantes de 8 comunidades autónomas españolas en edad escolar y se analizan las diferencias en función de variables sociodemográficas. Se emplea estadística no paramétrica con un grupo control y otro experimental. Los resultados señalan la correlación positiva entre las actitudes que muestran los alumnos y las habilidades emprendedoras que adquieren sin diferencias por género, siendo mayor el impacto en el grupo experimental. Se requiere fortalecer la adquisición de estas habilidades que promueven la identidad y la intención emprendedora.
Application of Modern Technologies in Notarial Activity in the Inheritance of Digital Financial Assets
Authors:   Udmurt State University, Artamkin Kirill
Published: March 2024

Introduction. Nowadays, digital financial assets are actively being introduced into civil circulation, but there is no established practice of inheriting this benefit. The purpose of the study is to determine the place of digital financial assets in the system of objects of civil rights, identify the problems of their acceptance and registration under the procedure of inheritance, and analyze the possibilities of using the unified portal of state and municipal services to solve these problems. In the paper, the author, relying on the dialectical method, analyzes digital financial assets and concludes that they belong to the objects of civil rights. The arguments are given for the use of the unified portal of state and municipal services to solve the problem of the heirs’ lack of an access key to the repository of digital financial assets. The conclusion is substantiated by the fact that it is impossible to implement this method of solving the identified problem without the state’s active participation.
Beyond the Model of a Teacher
Authors:   University of Silesia, Koziołek Krystyna
Published: March 2024

The post-structuralist theory of literature brings a new concept of reading. A reader is not only a receiver who should decipher a linguistic code, but s/he becomes the subject of plural operations of reading: understanding, associations, evaluation, feelings and emotions. And the most important thing: reading can transform a reader’s mind and his/her sensibilities. This broad concept of reading gives the teacher of literature fantastic possibilities. The territory of literature is the esthetic and moral space, where a pupil can compare his/her experience with other better or worse subject. In the first chapter I try to show that the compulsion of reading books at school is arbitrary and makes the system of the policy of education invisible. I claim that a teacher (not the reading list) is the model of value of literature. S/He has no choice - texts in the classroom have my face and my voice and I have to personally confirm their advantage to life. In the next chapters (“Situations of Readings”, “Awakenings”, “Jealousy and Reading”, “Inducing to Infidelity”) I show how the teacher can produce “the event of reading”, using emotions of intimate reading. Every strategy that I describe - strategy of situational teaching - has the same question: whether a given narrative will work for good or ill in the life of other readers, after the last page has been turned. Will this fiction help form a character who is hypersensitive, properly sensitive, or insensitive; intellectually pretentious, thoughtful, or shallow; rash, bold, or timid; bigoted or tolerant? The answering to the questions means to win the battle of myself.
Profiles of Gifted Students in Turkey
Authors:   Ondokuz Mayis University, Turkey, Gökdere M. , Çepni S. ,   Amasya Faculty of Education, Turkey
Published: March 2024

The purpose of this study is to determine the profiles and characteristics of the students at the six science-art centers in Turkey and to find out shortcomings of the current student identification system. In this research a case study approach was used, and data gathered with the help of a developed questionnaire. This questionnaire was delivered to 304 students who are educated at the Science-Art Centers in the cities of Bayburt, Bursa, İzmir, Sinop, Tekirdağ and Trabzon and 258 questionnaires returned. The data clarified that 36% of the sample’s mothers and 55% of their fathers were graduated from the universities. In addition, present gifted student-identification system is mostly concentrated on determining the students at upper class of society.
Social Climate in the School Classes for Gifted Children Compared with Regular School Classes
Authors:   Matej Bel University, Banská Bystrica, Slovak Republic, Flešková Marta
Published: March 2024

In this article we examine the results of the research on social climate in the school classes for gifted children in comparison with regular classes of the 1st stage elementary school. The research sample was made up by 36 children from 3 classes for gifted children and 73 pupils from regular classes. The research has proved some dissimilarity among monitored school classes as to how they perceive social climate evaluated by means of the questionnaire My Class Inventory. Gifted children have more difficulties in relationships, they are more competitive, less satisfied, and they feel to burdened by learning than pupils from regular classes.
ON THERMAL CONVECTION IN ROTATING CASSON NANOFLUID PERMEATED WITH SUSPENDED PARTICLES IN A DARCY-BRINKMAN POROUS MEDIUM
Authors: Sharma Pushap Lata , Bains Deepak , Rana Gian C.
Published: March 2024

The present paper investigates the effect of suspended particles on thermal convection in rotating Casson nanofluids saturating a Darcy-Brinkman porous medium which has various applications in different sectors, including those that process food, paint, water generators, electricity generators, hydrology, and geophysics, heavily rely on rotation in thermal convection. With the aid of the Galerkin 1st approximation technique, the numerical examination is carried out. The Darcy-Brinkman porous media and particles suspension are taken into consideration throughout the conduct of this study. The non-Newtonian Casson nanofluid, Darcy-Brinkman porous medium, particle suspension and rotation parameter, and their impact on thermal convection have been analyzed and presented graphically for free-free, rigid-rigid, and rigid-free boundaries. It is found that for all boundary conditions the Casson nanofluid and suspended particle parameters have destabilizing impact on the stationary convection, whereas the parameter which occurred due to presence of rotation, i.e., Taylor number and Brinkman porous medium parameters, both delayed the stationary convection. In addition, we have discovered that for realistic rigid-rigid boundary condition, the system is determined to be more stable than for the other two boundary conditions. Also, on the basis of several approximations on the Taylor number and other parameters, the critical wave number and value for stationary convection are determined.
Sensitivity investigation of drilling efficiency to operational parameters of a drifter
Authors: Shen Qiang , Wang Yujie , Cao Ruilang , Zhao Yufei , Liu Yaoru
Published: March 2024

Drilling operations are extensively used for underground excavation, and their efficiency has a direct impact on project duration and expense. Adjusting the operational parameters during the drilling process is important for improving drilling efficiency. In this study, the sensitivity of drilling efficiency to operational parameters was investigated. Full-scale drilling tests for a dolomite block were conducted using a hydraulic drifter, and the ‘measurement while drilling’ system was used to record the drilling data. Orthogonal schemes were designed to arrange the tests, and the penetration rate, specific energy and rate–energy ratio were regarded as evaluation indices to assess the drilling efficiency. The sensitivity of the evaluation indices to operational parameters was analysed using both range analysis and variance analysis. Results show that the optimal combination of parameters within the test range was determined to be the propelling pressure of 8.5 MPa, percussive pressure of 17.5 MPa and rotary speed of 250 r/min to obtain the maximum drilling efficiency. The sensitivity sequence of the rate–energy ratio was propelling pressure, percussive pressure and rotary speed, with weights of 54.0, 38.7 and 7.3%, respectively. These findings can provide a valuable reference for adjusting the operational parameters of hydraulic drifters to optimise drilling efficiency.
Development and Validation of Staging Systems for AA Amyloidosis
Authors: Basset Marco , Schönland Stefan O. , Obici Laura , Günther Janine , Riva Eloisa , Dittrich Tobias , Milani Paolo , Ferretti Virginia Valeria , Pasquinucci Ettore , Foli Andrea , Kimmich Christoph , Nanci Martina , Bellofiore Claudia , Benigna Francesca , Beimler Jörg , Benvenuti Pietro , Fabris Francesca , Mussinelli Roberta , Nuvolone Mario , Klersy Catherine , Albertini Riccardo , Merlini Giampaolo , Hegenbart Ute , Palladini Giovanni , Blank Norbert
Published: March 2024

Key Points

Patients with AA amyloidosis and age ≥65 years, eGFR <45 ml/min per 1.73 m2, and N-terminal type-B natriuretic peptide >1000 ng/L and/or type-B natriuretic peptide >130 ng/L at diagnosis have poorer survival.

Proteinuria >3.0 g/24 hours and eGFR <35 ml/min per 1.73 m2 identify patients at high risk of progression to end-stage kidney failure.

Prognostic stratification in AA amyloidosis can be easily made by staging systems, similarly to AL and transthyretin amyloidosis.

Background

The kidney is involved in almost 100% of cases of AA amyloidosis, a rare disease caused by persistent inflammation with long overall survival but frequent progression to kidney failure. Identification of patients with advanced disease at diagnosis is difficult, given the absence of validated staging systems.

Methods

Patients with newly diagnosed AA amyloidosis from the Pavia (n=233, testing cohort) and Heidelberg (n=243, validation cohort) centers were included in this study. Cutoffs of continuous variables were determined by receiver operating characteristic analysis predicting death or dialysis at 24 months. Prognostic factors included in staging systems were identified by multivariable models in the testing cohort.

Results

Age ≥65 years, eGFR <45 ml/min per 1.73 m2, and elevated natriuretic peptides (type-B natriuretic peptide >130 ng/L and/or N-terminal type-B natriuretic peptide >1000 ng/L) were associated with overall survival and included in the staging system (all with simplified coefficients 1). Mean 36-month overall survival was lower with higher staging system scores (score 0–1: 92%; score 2: 72%; score 3: 32%). These results were confirmed in the validation cohort. For kidney failure, variables selected to enter in the staging system model were proteinuria >3 g/24 hour and eGFR <35 ml/min per 1.73 m2 (both with simplified coefficients 1). The 36-month cumulative incidence of kidney failure was higher with higher staging system scores (score 0: 0%; score 1: 24%; score 2: 51%). Again, similar results were obtained in validation cohort.

Conclusions

We identified and validated biomarker-based staging systems for overall survival and kidney failure in AA amyloidosis.
Imitatio e aemulatio: a recepção de Marcial em Friedrich von Logau a partir de três epigramas
Authors: Porto Roberto Carlos Conceição
Published: March 2024

Resumo: este artigo analisa os epigramas satíricos de Friedrich von Logau (1605-1655), poeta alemão desconhecido no mundo lusófono. Epigramatista, Logau escreveu mais de três mil epigramas e Marcial, poeta romano do século I d.C. pode ser considerado um de seus principais modelos. Entretanto, até o presente momento, a recepção de Marcial em Logau não fora satisfatoriamente analisada, nem mesmo na Alemanha, terra natal do poeta. Esta pesquisa pretende examinar essa recepção a partir de três epigramas em que Logau imita ou emula Marcial. Para isso, investiga-se a origem e desenvolvimento do gênero epigramático, as principais características do gênero em Marcial, o contexto e as preceptivas poéticas humanistas (Scaliger e Opitz) epigramáticas, algumas marcas dos epigramas satíricos de Logau e, por fim, a imitação e emulação do poeta romano pelo alemão. Palavras-chave: Epigrama. Marcial. Friedrich von Logau. Epigrama satírico.
The transformative role of Computational Fluid Dynamics (CFD) in chemical engineering
Authors: Bibhab Kumar Lodh
Published: March 2024

Chemical engineering is a discipline intrinsically linked to fluid behavior. From reaction kinetics to reactor design, understanding how fluids flow, mix, and transfer heat is paramount. Traditionally, this relied heavily on experimentation, a time-consuming and resource-intensive process. The emergence of Computational Fluid Dynamics (CFD) has revolutionized the field, offering a powerful in-silico approach to analyze fluid dynamics in chemical engineering processes. This review paper explores the transformative role of CFD, examining its impact on various aspects of chemical engineering, including reactor design, optimization, process intensification, scale-up, and safety analysis. The paper also discusses the challenges associated with CFD simulations, ongoing advancements in the field, and potential future directions.
Sample vitrification for cryo-ET v1
Authors: zhao Dorothy
Published: March 2024

Aggregationof proteins containing expanded polyglutamine (polyQ) repeats is thecytopathologic hallmark of a group of dominantly inherited neurodegenerativediseases, including Huntington's disease (HD). Huntingtin (Htt), the diseaseprotein of HD, forms amyloid-like fibrils by liquid-to-solid phase transition.Macroautophagy has been proposed to clear polyQ aggregates, but the efficiencyof aggrephagy is limited. Here, we used cryo-electron tomography to visualizethe interactions of autophagosomes with polyQ aggregates in cultured cells insitu. We found that an amorphous aggregate phase exists next to theradially organized polyQ fibrils. Autophagosomes preferentially engulfed thisamorphous material, mediated by interactions between the autophagy receptor p62/SQSTM1and the non-fibrillar aggregate surface. In contrast, amyloid fibrils excludedp62 and evaded clearance, resulting in trapping of autophagic structures. Theseresults suggest that the limited efficiency of autophagy in clearing polyQaggregates is due to the inability of autophagosomes to interact productivelywith the non-deformable, fibrillar disease aggregates.
Thawing Frozen Adherent Cell Lines v1
Authors: Lopez Carolina
Published: March 2024

This protocol describes the procedures from thawing and expanding adherent cell lines
Correlated light-electron microscopy (CLEM) and cryo-focused ion beam (FIB) milling v1
Authors: zhao Dorothy
Published: March 2024

Aggregation of proteins containing expanded polyglutamine (polyQ) repeats is the cytopathologic hallmark of a group of dominantly inherited neurodegenerative diseases, including Huntington's disease (HD). Huntingtin (Htt), the disease protein of HD, forms amyloid-like fibrils by liquid-to-solid phase transition. Macroautophagy has been proposed to clear polyQ aggregates, but the efficiency of aggrephagy is limited. Here, we used cryo-electron tomography to visualize the interactions of autophagosomes with polyQ aggregates in cultured cells in situ. We found that an amorphous aggregate phase exists next to the radially organized polyQ fibrils. Autophagosomes preferentially engulfed this amorphous material, mediated by interactions between the autophagy receptor p62/SQSTM1 and the non-fibrillar aggregate surface. In contrast, amyloid fibrils excluded p62 and evaded clearance, resulting in trapping of autophagic structures. These results suggest that the limited efficiency of autophagy in clearing polyQ aggregates is due to the inability of autophagosomes to interact productively with the non-deformable, fibrillar disease aggregates.
HuBMAP | GE HealthCare/UPitt Cell DIVE™ and scRNA Modality Overview v1
Authors: McDonough Liz
Published: March 2024

This is an overview of all protocols currently in use for the 2024 GE HealthCare/UPitt collaboration for the Human BioMolecular Atlas Program (HuBMAP). It includes links to each of the individual protocols that make up this project workflow.
Splitting Adherent Cell Lines v1
Authors: Lopez Carolina
Published: March 2024

This protocol describes how to split and maintain adherent cell lines in culture. Examples of these cells are: A549 cells, LLCMK2 cells, and MDCK cells.
Group Self‐Interest vs. Equity: Explaining Support for Horizontal Redistribution in (Former) Competitive Clientelist States
Authors: Kuppens Line , Leopold Lucas , Langer Arnim
Published: March 2024

Extant literature links intergroup disparities, or horizontal inequalities, in Sub‐Saharan Africa to the unequal representation of ethnic groups in central power, who accumulate wealth at the expense of politically marginalized groups. Over time, these politically‐induced inequalities have trapped some ethnic groups in positions of relative disadvantage. Group‐based, or horizontal, redistribution can help redress these inequalities yet require popular support if they are not to contribute to intergroup tensions. In this article, we examine how people’s experiences of political exclusion, on the one hand, and their attributional beliefs about the causes of political exclusion, on the other, condition support for government policies aimed at eradicating economic inequalities between different ethnic groups. We argue that people are more likely to be supportive of horizontal redistribution either when (H1a) they belong to ethnic groups that have not had access to central power, and/or (H1b) feel that their ethnic group is politically marginalized (and thus stands to gain); or when (H2) they attribute the political exclusion of the politically marginalized group(s) that stand(s) to benefit from these policies to the legacies of colonialism and clientelism (thus seeking to foster equity). To test our hypotheses, we examine these issues in the context of Kenya, a society with politically salient ethnic cleavages and a history of clientelism. Based on a unique online survey involving 2,286 Kenyans, we show that, notwithstanding group self‐interest being at play, there is strong support for horizontal redistribution across groups.
Inclusion or Exclusion? The Spatial Habitus of Rural Gentrifiers
Authors: Tomay Kyra , Berger Viktor
Published: March 2024

Several rural areas all over the world have experienced the inflow of the urban better‐off. This rural gentrification takes various temporary and permanent forms, i.e., lifestyle migration, second‐home ownership, or short‐term visitors. Scholarly interest in rural gentrification is evidenced by the growing body of literature. Based on 105 semi‐structured in‐depth interviews conducted in two rural areas in Hungary, this article aims to explore the perceptions, motivations, preferences, and lived experiences of rural newcomers, their position within the community, as well as processes of inclusion and exclusion. We rely on Pierre Bourdieu’s concept of habitus and argue that it includes distinct spatial dispositions forming a “spatial habitus.” The interviews show that the middle‐class rural gentrifiers’ (spatial) habitus is entangled with their cultural capital and represents a mixture of urban and “ruralising” dispositions. Their spatial practices are interpreted as the result of middle‐class (spatial) habitus and middle‐class symbolic distinction. At the same time, middle‐class rural gentrifiers are active local agents who defy common notions of newcomers having to integrate into their communities of choice.
CORE COMPETENCY IN RESEARCH OF TEXTS CALLING FOR UNDERMINING THE CONSTITUTIONAL ORDER, TERRITORIAL INTEGRITY AND SOVEREIGNTY OF UKRAINE
Authors:   National Academy of the Security Service of Ukraine, Chernyak A. M.
Published: March 2024

In a situation where our state has faced a significant number of threats from the Russian Federation, among which threats of information terrorism and extremism represent a significant part of the existing risks, the number of criminal investigations into the facts of committing such crimes has increased. The investigation of almost each of them is associated with the need to use particular knowledge to ensure completeness, comprehensiveness, objectivity and at the same time compliance with reasonable deadlines for pre-trial investigation. The peculiarity of a significant number of modern expert studies conducted in criminal proceedings on extremist crimes is that their objects are products of speech activity which find their expression in oral or written speech and are stored on a storage medium in graphic or digital forms. Both data storage materials and the speech product stored on them are subject to expert research. The aim of research is to analyse the practice of using the capabilities of forensic examination in order to study texts during the pre-trial investigation of crimes related to public calls for committing illegal actions aimed at undermining the constitutional order, territorial integrity and sovereignty of Ukraine; to reveal the potentials of linguistic expert examination and to justify the need for comprehensive psychological and linguistic studies of texts calling for the perpetration of illegal actions, as well as denial of the legitimacy of resolving legal issues during such examinations. The study substantiates that the most important tool for identifying, investigating and proving facts of extremist activities aimed at undermining the constitutional order, territorial integrity and sovereignty of Ukraine are forensic examination and expert research. Manifestations of speech extremism become frequent objects of study in forensic linguistic examination. When translating the signs of such extremist crimes into a meta-language of linguistic semantics, two groups of features are distinguished – semantic and pragmatic. By virtue of introduction of the methodology for conducting forensic linguistic, psychological and linguistic examination of materials in criminal proceedings related to the investigation of the facts of calls for extremism and terrorism, modern experts are armed with a system of linguistic categories and methods that must be used in the study of statements that have fallen into the legal sphere. Forensic examinations in such criminal proceedings are also a means of remedial action, since the correctness of its expert evaluation depends on an objective, methodically correct expert assessment of the disputed material. Due to the verbal nature of the objects of expert research, bodies of pre-trial investigation most often appoint forensic linguistic, psychological, psycho-linguistic, and other examinations, as well as various options for complex research.