bluuebunny/crossref_metadata_2025 huggingface dataset:
Approaching bibliometrics and prosopography: The comprehensive publishing landscape of CNPq (Brazil) and CONICET (Argentina) and its coverage in global databases
Authors: Digiampietri Luciano , Gallardo Osvaldo , Baranger Denis , Beigel María Fernanda
Published: October 2024

Global databases such as Web of Science and Scopus have determined the standard indicators to measure the research output in national comparisons and its quality evaluation for decades. Already classic studies of science proved that this landscape of scientific production was distorted by using overly selective bibliographical indexes that were considered “international databases” while their coverage was severely limited. A relevant part of the bibliometric literature in the last 10 years has revolved around the limitations of these global data sources and the search for alternatives to explore more comprehensive universes of the scholarly output, considering all disciplines and languages. Particularly relevant in this debate are some recently created bibliographic services and search engines that provide new opportunities: Dimensions, Lens, Open Alex, CrossRef and Google Scholar. Our specific contribution to these studies relies on a methodological shift based on a convergence between prosopography and bibliometrics. For that end, we selected two countries that can be considered “peripheral centers” in the Latin American region. Firstly, we determined a universe of national researchers of the National Council for Scientific and Technological Development (CNPq, Brazil) and the National Council for Scientific and Technical Research (CONICET, Argentina). The target populations are composed of 10,619 tenured researchers at CONICET and 14,418 holders of the CNPq’s “research productivity fellowship”. Secondly, we built a database with their comprehensive publishing performance uploaded in the national curricular information systems, the Brazilian Lattes and Argentina’s SIGEVA, that includes metadata for all articles. After computational and manual data cleaning of this database, we retained a total 464,361 articles for Brazil and 81,005 for Argentina published in 2013-2020. The comparative study shows that Argentina and Brazil have similar patterns of coverage in the global databases, although they differ in terms of collaboration practices and national publishing.
Ocular Vestibular-Evoked Myogenic Potentials in Individuals with Diabetes Mellitus: A Systematic Review and Meta-Analysis
Authors: Jose Maria , Kumar Kaushlendra , Narayan Amitesh
Published: October 2024

Studies on ocular vestibular evoked myogenic potentials (VEMPs) in individuals with diabetes mellitus (DM) are inconsistent. The current study aimed to systematically review and report on existing studies on oVEMPs in DM. We performed a systematic review following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. To be included in the review and subsequent meta-analysis, the study had to report on ocular VEMPs (oVEMP) in DM individuals with and/or without peripheral neuropathy (PN). A search strategy for each of the major electronic databases was developed using the key words "diabetes mellitus" and "vestibular evoked myogenic potential" or "VEMP." A three-phase selection process was used for the final inclusion of studies, and the methodological quality of these studies was assessed using the Newcastle Ottawa scale (NCOS). Meta-analysis was performed using a random-effects model, and the statistical heterogeneity was computed using the I2 index. For comparisons between DM and healthy controls, a significant difference was observed for oVEMP p1 latency (P = 0.03), and amplitude (P = 0.03). The nature of vestibular dysfunction in DM remains inconclusive. The results of our meta-analysis suggest that both central and peripheral vestibular dysfunction can be observed in DM. It appears that VEMPs may be useful in the early detection of neuropathy in DM. Prospective, well-designed studies are needed to investigate vestibular (dys)function in DM.
Regional Differences of Women’s Online Shopping Behaviour in Kazakhstan: An In-Depth Analysis of the Factors
Authors:   Institute of Economics of the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan, Kireyeva A.A. , Nurbatsin A. S. ,   Kenzhegali Sagadiyev University of International Business, Orynbet P. Zh. ,   Turan University
Published: October 2024

Despite the growing popularity of online shopping, there is a lack of research on regional differences in consumer behaviour and preferences, particularly among women. The study aims to investigate the regional differences in women’s online shopping behaviour in Kazakhstan by conducting an in-depth analysis of the factors influencing female consumers. Using data from a survey of 400 women across different regions of Kazakhstan, logistic regression analysis was utilised to examine the relationship between online shopping frequency and several independent variables. The analysis found that the pandemic significantly affected online shopping behaviour in Kazakhstan, leading to decreased shopping frequency across all regions. Additionally, we found that women living in urban areas were significantly more likely to shop online frequently than those in rural areas, with an odds ratio of 0.504 (p = 0.014). The research also revealed notable differences in Internet penetration rates, with Karaganda, Pavlodar regions and Astana city having the highest rates among women (93.1 %, 93.0 %, and 94.5 %, respectively), while Atyrau and Kyzylorda regions had the lowest (80.7 % and 80.0 %). Therefore, it is recommended that policymakers should focus on expanding Internet infrastructure in remote regions by developing customised online marketplaces that meet the needs of urban areas like Almaty city. The findings of this study underscore the importance of considering regional differences in understanding the factors that drive online shopping behaviour in Kazakhstan. By investing in initiatives that promote e-commerce adoption and cater to consumers’ unique needs and preferences in different regions, policymakers can help foster a more inclusive and dynamic e-commerce ecosystem in Kazakhstan.
FIGHTER BATTALIONS OF LENINGRAD AND THE REGION UNDER SIEGE. 1941–1944
Authors:   St. Petersburg Institute of History, Russian Academy of Sciences, Medvedev T.D.
Published: October 2024

The paper analyzes the operations of NKVD fighter battalions in Leningrad and the surrounding region from 1942 to 1944, using previously unpublished sources from the Central State Archive of Historical and Political Documents in St. Petersburg (TSGAIPD). These sources include official NKVD documents, relevant statutes, and statistical data. The article examines the effectiveness and models of the use of these units in the challenging circumstances of besieged Leningrad, as well as territories of the region, including those outside the blockade ring. Particular focus is given to the support provided to Leningrad's fighter battalions and the restructuring of the unit system during the brutal first winter of the blockade. Additionally, the paper analyzes the management practices of the Leningrad fighter battalions and their transformation in response to changing situations at the front and in the rear. Attention is also paid to the use of these units during the blockade and after its breakthrough, leading to the final liberation of the region from occupation. The author examines the gender, social, and professional composition of the fighter battalions in the city and the region, as well as the dynamics of their numbers. The author concludes that while the effectiveness of the fighter battalions operating in Leningrad and the region was limited, leading to an op-erational reduction in the number of personnel of the city battalions during the winter of 1942, the fighter units re-mained actively deployed as auxiliary forces until their disbandment. They played crucial roles in maintaining order and controlling territory near the frontlines.
KONSTANTIN ILYICH SHNEIDER IS 60. SKETCHES FOR AN INTELLECTUAL BIOGRAPHY
Authors:   Perm State Institute of Culture, Leybovich O.L. , Shelokhaev V. V. ,   Institute of Russian History, Russian Academy of Sciences, Narskii I.V. ,   Perm State University
Published: October 2024

In 2024, Konstantin I. Shneider, a well-known historian and specialist in the intellectual history of Russia, Doc-tor of Science in History, Head of the Department of History and Archaeology at Perm State National Research Uni-versity, celebrates his 60th birthday. To commemorate this milestone, his colleagues and friends in academia have come together to write reflections on different stages of his professional career, each in their own unique style. Oleg L. Leibovich reflects on the initial stage of Professor Shneider’s intellectual biography (1986–1993), paying attention to his search for a life path after graduating from the Faculty of History at Perm State University. The piece also touches upon the problem of the choices Shneider faced during this time, as well as his scientific collaboration with Professor Zakhar I. Fainburg. Valentin V. Shelokhaev responds to Schneider’s concept of early Russian liberalism, which was further developed in his monograph and doctoral dissertation (2013). Igor V. Narskii refers to his personal experience of many years of professional and friendly interaction with Schneider to create a sketch of his intellectual biography as a specialist in intellectual history. The human dimension of the researcher and the researched, despite the ironic style of presentation, becomes an organic component of intellectual (auto)reflection
HISTORY OF STUDYING ANTHROPOLOGICAL MATERIAL COMING FROM NECROPOLIS FROM THE TERRITORY OF THE PERM CIS-URAL REGION
Authors:   Institute for Humanitarian Studies, Perm Federal Research Center, Ural Branch, Russian Academy of Sciences, Bryukhova N. G. ,   Perm State Humanitarian and Pedagogical University
Published: October 2024

The article deals with the problem of studying anthropological material from the territory of the Perm Cis-Urals region. The author identifies three chronological stages of the publication activity among researchers and analyzes the periods of increased interest in paleoanthropology of the region. The first anthropological studies in the Perm region were conducted in the late 19th century by N.M. Maliev, who analyzed materials from the Kudymkar cemetery. However, research during this stage was sporadic and there were no local anthropologists in the re-gion. The Soviet stage of research, which took place in the second half of the 20th century, was associated with large-scale archaeological excavations in the Perm Cis-Urals, including the Mitinsky and Demenkov-sky cemeteries, which contained well-preserved anthropological remains. Moscow anthropologists M.S. Akimova, V.P. Alekseev, and S.G. Efimova presented paleoanthropological analysis, dealing with the issues of racial genesis, as as there were still no local specialists in paleoanthropology. The most recent stage of research, referring to the early 21st century, is characterized by new archaeological excavations at the burial grounds in the Perm Cis-Urals, as well as the emergence of regional researchers and a broader range of topics being explored. The paper also describes the difficulties that anthropologists face when working with human bones. There are still many white spots on the anthropological map of the region, which do not yet allow the researchers to see the full picture of region’s population movements in antiquity. The gaps can potentially be filled by new anthropo-logical material obtained from recent excavations of ancient burial grounds and necropolises of Modern times.
M. S. Rogovin and the study of the concepts of psychological science
Authors:   Yaroslavl State Pedagogical University named after K.D. Ushinsky, Mazilov V.A. , Vlasov N.A. ,   Psychiatric Hospital No.4 named after P.B. Gannushkin; Russian State Social University
Published: October 2024

The article analyzes the role of M.S. Rogovin in the formation of the tradition of research of individual concepts and systems of concepts of psychological science, which have become especially relevant in the last decade. It is argued that M.S. Rogovin was the first Russian scientist who not only posed this problem, but also systematically approached the development of the conceptual field of psychological science back in the late 1960s. It is shown that one of the main disadvantages of psychology that prevent its transformation into a fullfledged science, similar to natural disciplines, is the weak reflection and insufficient integration of its basic concepts, and the main difficulty in studying them is the dual nature of concepts that act both as a means of fixing and transmitting experience, and as its result. On the peculiarities of the concepts of psychological science M.S. Rogovin attributes their imagery, polarization, uncertainty, one-sidedness and exposure to the influence of certain psychological concepts, such as structural and functional directions in psychology. In general, the scientist recognizes the weak integration of psychological knowledge and concepts, "with reservations" combined into a system. The authors characterize the dynamics of the concepts of psychology, which is determined by two parallel and continuous processes – differentiation caused by the receipt of new empirical, primarily experimental data on the mental, and the establishment of relations between these concepts. The problem of explanation is analyzed, in relation to psychology, characterized by a multiplicity of variants of interpretation of causality and a tendency to various types of reduction, primarily to such as biological and social. As an effective way of integrating the concepts of psychology, the approach proposed by M.S. Rogovin is described, which consists in identifying the patterns underlying various types of explanation. The features and prospects of the structural-level concept developed by the scientist in psychology are considered. The article concludes by emphasizing the problems and ideas of the scientist that remain relevant in our time.
Streebog as a random oracle
Authors:   CryptoPro, Akhmetzyanova L.R. , Babueva A.A. ,   CryptoPro, Bozhko A.A. ,   CryptoPro
Published: October 2024

The random oracle model is an instrument used for proving that protocol has no structural flaws when settling with standard hash properties is impossible or fairly difficult. In practice, however, random oracles must be instantiated with some specific hash functions that are not random oracles. Therefore, in the real world an adversary has broader capabilities than considered in the random oracle proof: it can exploit the peculiarities of a specific hash function to achieve its goal. In a case when a hash function is based on some building block, one can go further and show that even if the adversary has access to that building block, the hash function still behaves like a random oracle under some assumptions made about the building block. Thereby, the protocol can be proved secure against more powerful adversaries under less complex assumptions. The notion of indifferentiability formalizes that approach. In this paper, we show that Streebog, a Russian standardized hash function, is indifferentiable from a random oracle under an ideal cipher assumption for the underlying block cipher.
Database analysis of optimal double-loop networks
Authors:   Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Monakhova E.A. , Monakhov O.G. ,   Institute of Computational Mathematics and Mathematical Geophysics SB RAS
Published: October 2024

Optimal circulant networks are of practical interest as models of reliable low-latency communication networks for multiprocessor cluster systems and on-chip networks. The authors are the first to construct a large dataset of optimal diameter doubleloop circulant networks with up to 50 thousand nodes, containing a complete set of optimal graph generators. The analysis of the dataset has been carried out in order to study the problem of finding analytically defined families of optimal graphs. Two new algorithms for automatically finding analytical descriptions of optimal graphs families described by polynomials in diameter have been developed. Using the implemented algorithms, a large number of new analytically described families of optimal networks have been found and tested using validation over the entire range of changes in the diameters of the dataset graphs. The found families of optimal networks can be used when scaling information transmission algorithms in double-loop circulant structures.
On the generic complexity of solving equations over natural numbers with addition
Authors:   Sobolev Institute of Mathematics, Rybalov A.N.
Published: October 2024

We study the general complexity of the problem of determining the solvability of equations systems over natural numbers with the addition. The NP-completeness of this problem is proved. A polynomial generic algorithm for solving this problem is proposed. It is proved that if P ̸= NP and P = BPP, then for the problem of checking the solvability of systems of equations over natural numbers with zero there is no strongly generic polynomial algorithm. For a strongly generic polynomial algorithm, there is no efficient method for random generation of inputs on which the algorithm cannot solve the problem. To prove this theorem, we use the method of generic amplification, which allows us to construct generically hard problems from problems that are hard in the classical sense. The main feature of this method is the cloning technique, which combines the input data of a problem into sufficiently large sets of equivalent input data. Equivalence is understood in the sense that the problem is solved similarly for them.
Makespan minimization in reentrant flow shop problem with identical jobs
Authors:   Dostoevsky Omsk State University, Romanova A.A. , Servakh V.V. ,   Sobolev Institute of Mathematics, Tavchenko V.Yu. ,   Dostoevsky Omsk State University
Published: October 2024

We consider the reentrant flow shop problem F|reentrant, pij = pi |Cmax with identical jobs and makespan criterion. We prove its NP-hardness in the ordinary sense. The proof is performed by polynomial reduction of the problem J3|n = 3|Cmax to the problem F|reentrant, pij = pi |Cmax with three identical jobs. Using the input data of the problem J3|n = 3|Cmax, we have constructed a special type of job for the problem F|reentrant, pij = pi |Cmax. In the proof, we analyze all possible variants of critical paths in the constructed instance. We also propose a dynamic programming algorithm to find the optimal solution of the problem F|reentrant, pij = pi |Cmax. Analysis of the time complexity of the algorithm showed that the problem with fixed number of jobs is pseudopolynomially solvable. Next, we study the use of cyclic schedules to construct approximate solutions. A cyclic schedule with a minimum cycle time can be found in polynomial time. We propose a polynomial algorithm for finding an approximate solution. This algorithm is based on the construction of a cyclic schedule with a minimum cycle time and its subsequent compaction at the beginning and at the end. We construct an upper bound of the makespan of cyclic schedules. This bound depends on the number of jobs processed in one cycle. The paper provides numerous examples characterizing cyclic schedules from both the positive and negative sides to solve the problem F|reentrant, pij = pi |Cmax.
A Dupla Transparência nas Apresentações de Si de Iniciativas Brasileiras de Vigilância Civil Sobre Transparência Pública
Authors: Silva Daniel Reis , Melo Fernanda Shelda de Andrade
Published: October 2024

O artigo reflete sobre iniciativas de vigilância civil brasileiras que versam sobre a transparência pública, entendendo-as como parte de um fenômeno de democracia monitória conformado nas últimas décadas com implicações para o sistema político e midiático. De caráter descritivo, desenvolve uma análise acerca de como essas iniciativas, ancoradas discursivamente na defesa do interesse público e na cobrança por transparência, dão (ou não) visibilidade para os seus próprios elementos formativos e operacionais, em uma hipótese nomeada de “dupla transparência”. Para tanto, o artigo desenvolve uma recuperação teórica sobre a transparência pública no sistema democrático e no caso brasileiro, aborda a democracia monitória e a vigilância civil, pensando nos desafios das iniciativas na construção de sua legitimidade, assim como suas interfaces com o sistema midiático. Em seguida, são analisadas seis iniciativas brasileiras contemporâneas sobre o tema, a partir de uma busca em seus websites acerca de discursos sobre quatro categorias: (a) origem, (b) equipe, (c) financiamento, e (d) parcerias. Como resultado, o artigo constata que as iniciativas em questão aplicam de forma deficitária e variada, de acordo com sua própria natureza de monitoramento, a ideia de “dupla transparência”, falhando, especialmente, em apresentar informações sobre suas fontes de financiamento e gastos, construindo sistemas opacos nos quais interesses privados podem ser escondidos.
Screening and validating genes associated with cuproptosis in systemic lupus erythematosus by expression profiling combined with machine learning
Authors: Xia Zhongbin , Cheng Ruoying , Liu Qi , Zu Yuxin , Liao Shilu
Published: October 2024

Cell death has long been a focal point in life sciences research, and recently, scientists have discovered a novel form of cell death induced by copper, termed cuproptosis. This paper aimed to identify genes associated with cuproptosis in systemic lupus erythematosus (SLE) through machine learning, combined with single-cell RNA sequencing (scRNA-seq), to screen and validate related genes. The analytical results were then experimentally verified. Two published microarray gene expression datasets (GSE65391 and GSE61635) from SLE and control peripheral blood samples were downloaded from the GEO database. The GSE65391 dataset was used as the training group, while the GSE61635 dataset served as the validation group. Differentially expressed genes from GSE65391 identified 12 differential genes. Nine diagnostic genes, considered potential biomarkers, were selected using the least absolute shrinkage and selection operator and support vector machine recursive feature elimination analysis. The receiver operating characteristic (ROC) curves for both the training and validation groups were used to calculate the area under the curve to assess discriminatory properties. CIBERSORT was used to assess the relationship between these diagnostic genes and a reference set of infiltrating immune cells. scRNA-seq data (GSE162577) from SLE patients were also obtained from the GEO database and analyzed. Experimental validation of the most important SLE biomarkers was performed. Twelve significantly different cuproptosis-related genes were identified in the GSE65391 training set. Immune cell analysis revealed 12 immune cell types and identified nine signature genes, including PDHB, glutaminase (GLS), DLAT, LIAS, MTF1, DLST, DLD, LIPT1, and FDX1. In the GSE61635 validation set, seven genes were weakly expressed, and two genes were strongly expressed in the treatment group. According to the ROC curves, PDHB and GLS demonstrated significant diagnostic value. Additionally, correlation analysis was conducted on the nine characteristic genes in relation to immune infiltration. The distribution of key genes in immune cells was determined using scRNA-seq data. Finally, the mRNA expression of the nine diagnostic genes was validated using qPCR.
Effects of Intraoperative Hypothermia on Patients Undergoing Laparoscopic Surgery: A Retrospective Cohort Study v1
Authors: oofuvong maliwan
Published: October 2024

This study aims to explore the association between intraoperative hypothermia andoutcomes in adult patients undergoing laparoscopic surgery. A retrospective analysis of 2048 adult laparoscopic surgery patients treated between 2020 and 2021 was conducted at Songklanagarind Hospital, Thailand.Intraoperative hypothermia, defined as a core temperature below 36 ˚C, was recorded as either one or more than one episode. Patient demographics, clinical information and postoperative outcomes were extracted from the hospital informationsystem. The outcomes were intraoperative and postoperative cardiac arrhythmias, postoperative oxygenrequirement, length of post-anesthetic care unit (PACU) stay, and length of hospital stay. Univariate and multivariate logistic/linear regression models were fit to assess the association between hypothermia and outcomes, presented as odds ratio (OR) or beta-coefficient (b) with 95% confidence interval (CI).
GoT-ChA: Genotyping of Targeted loci with single-cell Chromatin Accessibility v1
Authors: Izzo Franco , Raimondi Ivan
Published: October 2024

Somatic mutations are crucial for cancer initiation and evolution, and have been identified across a number of healthy tissues in the human body. These mutations can disrupt normal cellular functions, leading to aberrant clonal expansions via acquired fitness advantages or skewed differentiation topologies. GoT-ChA and similar methods (e.g. GoT, TARGET-seq) aim to pair targeted genotyping with single-cell sequencing approaches in order to understand the impact of somatic mutations directly in human patient samples, in both malignant and non-malignant contexts. GoT-ChA is unique in that it is a high-throughput single-cell method that pairs targeted genotyping with chromatin accessibility measurements based on the broadly utilized scATAC-seq platform from 10x Genomics. Previous single-cell genotyping approaches were largely based on scRNA-seq protocols, utilizing expressed and captured mRNA transcripts as sources for genotyping information. This results in a limiting dependence on gene expression and mutation location (due to 3' end bias of most scRNA-seq methods), precluding the usage of such technologies on lowly expressed or inconveniently located loci of interest. GoT-ChA surmounts these limitations via direct utilization of genomic DNA for genotyping, whilst simultaneously assaying chromatin accessibility.
Semantic Change in PL-SKT Loanwords and Figures of Speech Used in the Tai Epic Thao Hung or Cheuang
Authors: Pimpuang Kowit , Yuttapongtada Methawee , Sunghor Noppawan
Published: October 2024

Thao Hung or Cheuang has been one of the important poetic works in Northern Laos and Northeastern (NE) Thailand for a long time. The use of Pali and Sanskrit (PL-SKT) words and their meanings in communicating the contents of the story in Northern Laos and Northeastern (NE) Thailand are a fascinating feature of this work. The objectives of this study were to explore the semantic changes in the PL-SKT loanwords, and to explore figures of speech in Thao Hung or Cheuang. The conceptual framework of this study consists of exploring 1) the use of PL-SKT words through semantic change processes and 2) the figures of speech used in Thao Hung or Cheuang. A qualitative method was employed and the data collection was done from the volumes 1-4 of Thao Hung or Cheuang Northeastern Literature Dictionary complied by the Royal Society of Thailand. It was found that there are 679 PL-SKT loanwords in 807 stanzas (Klong) of Thao Hung or Cheuang. Three processes of semantic change, namely, widening of meaning, narrowing of meaning and transferring of meaning, were employed in PL-SKT words. Furthermore, the following seven figures of speech: simile, metaphor, symbol, personification, hyperbole, onomatopoeia, and metonymy were found.
Teachers’ and Students’ Attitude Towards Flipped Teaching in EFL Classroom in Higher Education
Authors: Ha Nguyen Thi Dieu
Published: October 2024

Flipped teaching has become a continuous trend since COVID – 19 pandemic when online learning was popular more than ever. Following this model of teaching, teachers are required to record videos on the subjects that they are teaching before sharing them with students. This study aims at exploring both EFL teachers’ and students’ attitude towards the employment of flipped teaching at higher education level. The participants were 10 teachers and 10 students majoring in English Language Teaching and English Language at a university in Viet Nam. To collect data, semi-structured interviews were conducted. The results show that while teachers’ preparation and students’ engagement, interaction, critical thinking, and relevant learning style are amongst the positive attitudes, less motivation, more pressure, distraction, and lack of responsibility are considered as the negative feelings on flipped teaching. Suggestions for further studies are also presented.
On the problem of neuropathic pain component diagnosis in patients with cancer pain syndrome
Authors: Spasova A. P. , Dorozhenko A. M. , Ryazankina A. A. , Barysheva O. Yu. , Burganova A. N. , Goncharova E. V.
Published: October 2024

Neuropathic pain component occurs in every second patient with pain syndrome caused by a malignant tumor. Detection of the neuropathic component of pain syndrome is crucial for selection of effective analgesia.

The review presents an application algorithm for an updated system of neuropathic pain component assessment in oncological patients.
Problems and their solutions in accompanying therapy of oncological patients: regulatory and financial strategic approaches to solutions
Authors: Gabay P. G.
Published: October 2024

Accompanying therapy (AT) is vital for oncological patients as it allows to alleviate complications associated with both cancer and antitumor therapy. These complications include anemia, febrile neutropenia, nausea, and chronic pain syndrome. The problem is that many patients do not receive sufficient AT because of the lack of clinical guidelines and regulations. Currently, clinical guidelines only for anemia are approved and none for the other complications. The main barriers are the absence of legislative funding of AT and impossibility to obtain medications on the outpatient basis. The system of clinical-statistical disease groups also causes difficulties with payment for medical treatment. Low cost ratios and impossibility to combine AT payment with payment for the main therapy also limit its availability.

To solve these problems, separate clinical guidelines for AT should be developed, tariffs for the clinical-statistical disease groups should be revised, and coefficients of treatment complexity should be increased for wider medication coverage.
UNRAVELING THE COMPLEXITIES OF THERMAL RADIATION AND ROTATIONAL DYNAMICS IN PARABOLIC FLOW: A PERSPECTIVE
Authors: Sebastian Dilip Jose , Veeramani Mercy Priya , Shanmugam Buvaneswari , Kandhasamy Selvaraj , Rajakrishnan Balakumar , Ayothi Selvaraj , Devi Lakshmikaanth
Published: October 2024

The current study investigates the impact of thermal radiation in a scenario without magnetohydrodynamics (MHD) on a swaying current, while an extremely uniform vertical plate with an attached pile transmission has been considered in the examination. Although calculations were made, the precise nature of this impact remains uncertain. Both the plate temperature and the nearby concentration level increased evenly and consistently. The Laplace transform was employed to derive the dimensionless form. Various physical attributes, such as the thermal Franz Grashof number, mass Franz Grashof number, radiation parameter, Schmidt number, and the Ludwig Prandtl number, were considered. These attributes account for the effects of quickness, thermal state, and the number of species dissolved in the fluid. The profiles are graphically illustrated. An increment in the thermal (or mass) Grashof number leads to higher quickness values. Concerning the thermal luminosity attributes, there is an observed inversion in the trend.
COMPUTATIONAL HEMORHEOLOGY OF BLOOD FLOW WITH TiO2 NANOPARTICLES OVER A NON-LINEARLY STRETCHING SHEET UNDER MAGNETOHYDRODYNAMICS
Authors: Zuberi Haris Alam , Lal Madan , Zainal Nurul Amira
Published: October 2024

This study presents a computational analysis of the hemorheology of blood flow containing TiO2 nanoparticles over a non-linearly stretching sheet under the influence of magnetohydrodynamics (MHD). The Sisko blood flow model is employed to capture the non-Newtonian characteristics of the blood. The governing equations are derived and transformed into a set of non-linear ordinary differential equations (ODEs) using appropriate similarity variables. These equations are then solved numerically using the 4th-5th order Runge-Kutta-Fehlberg (RKF45) method. The results demonstrated that an increase in Sisko material parameter enhances the velocity of nanofluid. Increase in non-linear stretching parameter leads to a thinner boundary layer, thereby enhancing heat transfer at the surface. The findings underscore the potential of TiO2 nanoparticles in significantly improving heat transfer efficiency in biomedical and industrial applications.
INTEGRATING AI-BASED SPEECH RECOGNITION TECHNOLOGY TO ENHANCE READING ASSESSMENTS WITHIN MOROCCO’S TaRL PROGRAM
Authors: Bachiri Younes Aziz , Mouncif Hicham , Bouikhalene Belaid , Hamzaoui Radoine
Published: October 2024

This study examined the integration of artificial intelligence-powered speech recognition technology within early reading assessments in Morocco’s Teaching at the Right Level (TaRL) program. The purpose was to evaluate the effectiveness of an automated speech recognition tool compared to traditional paper- based assessments in improving reading skills among 100 Moroccan first to third-graders. The mixed- method approach combined pre-post standardized reading tests with qualitative feedback. Results showed students receiving the AI-enabled speech recognition assessments demonstrated significant gains in reading achievement compared to peers assessed via traditional methods. Qualitative findings revealed benefits of instant feedback and enhanced engagement provided by the speech recognition tool. This study contributes timely empirical evidence on adopting learning technologies, specifically AI-driven automated speech assessment instruments, to enhance foundational literacy development within under-resourced education systems implementing student-centered pedagogical techniques like TaRL. It provides valuable insights and guidance for integrating innovative speech analysis tools within localized teaching and learning frameworks to strengthen early reading instruction and monitoring.
THE INVIGILATOR APP AND SOME VUCA ELEMENTS IT TRIGGERS IN STUDENTS AND LECTURERS DURING ONLINE EXAMINATIONS: A CASE STUDY OF AN ENGLISH STUDIES MODULE AT UNISA
Authors: Chaka Chaka , Shange Thembeka
Published: October 2024

This study reports on the experiences students registered for a first-year, undergraduate English Studies module and English Studies lecturers had with the Invigilator app during an online examination in the first semester of 2023. Current research indicates that e-proctoring induces anxiety and uncertainty in students when they write online examinations. However, there is a paucity of research on the VUCA elements that the Invigilator app triggers in students and in lecturers during online examinations. The study was informed by a critical data surveillance framing, and it used convenience sampling to collect data through semi-structured interviews with seven lecturers (n = 7) for various undergraduate English Studies modules. Additionally, it employed purposive sampling to collect data from five (n = 5) email queries sent by five first-year, undergraduate English Studies module students to their lecturers when they experienced problems with the Invigilator app during their online examination. The findings indicate that lecturers and students struggled with the Invigilator app as an e-proctoring tool. Future research should focus on other less-invasive and better AI-proof assessment methods of maintaining academic integrity in online assessments.
The Light Triad of Personality: A Review of Foreign Studies
Authors: Maralov V.G.
Published: October 2024

The relevance of the problem is due to the importance of identifying integrated characteristics of a person, which would reflect his typical modes of behavior, activity and relationships to the world around him. Such characteristics include the concepts of Dark (Machiavellianism, narcissism, psychopathy) and Light (faith in humanity, humanism, Kantianism) personality triads. And, if the Dark Triad of traits has been actively studied in psychology for more than 20 years, the Light Triad has recently received the status of an independent psychological problem. Nevertheless, it aroused great interest in modern psychology, which led to the appearance of a significant number of publications. The article provides an overview of a number of modern foreign studies of the traits of the Light Triad of personality in the period from 2018 to 2024. Various approaches to identifying the features of the Light Triad and to developing diagnostic tools are considered. The main directions of research of the Light Triad are identified and characterized: the study of the manifestations of the features of the Light Triad depending on economic, political and cultural conditions; study of the relationship between the Light Triad traits and value orientations and life satisfaction; studying the relationship between the traits of the Light Triad and people’s behavior, including behavior on the Internet; traits of the Light Triad and the problem of leadership, etc. Disputable issues identified during the analysis of research on the traits of the Light Triad of personality are discussed.
Age Dynamics of the Development of Visual-Spatial Perspective-Taking
Authors: Krichka M.N.
Published: October 2024

The article presents an overview of foreign studies of the visual-spatial perspective-taking as the ability to determine what the other person sees. This phenomenon was first described by J. Piaget, but his study remains relevant to this day. As the analysis of modern scientific sources has shown, altercentric interference can contribute understanding of Level 1 perspective-taking; the development of Level 2 perspective-taking is closely related to the formation of navigation skills and mental rotation, and with the optimization of the use of spatial reference systems. An allocentric frame of reference goes pass a long way of formation throughout the preschool period: from the geometry of space and local landmarks to the configuration of array elements. The geometry of the array, as a form of spatial connections between objects, remains stable in relation to the target even with mental rotation. Accordingly, the more formed allocentric frame of reference a child uses, the more effectively he can perceive another's viewpoint. This pattern should be taken into account in further studies of perspective-taking.
The Methodology of "Responsibility in Adolescents": Development and Description
Authors: Danilova E.E. , Begunova L.A. , Lisichkina A.G. , Andreeva D.A.
Published: October 2024

The article presents the results of the development and standardization of the author’s methodology “Responsibility in Adolescents”, aimed at studying the basic mechanisms of responsibility and the areas of its implementation in the everyday life of older adolescents aged 16-19 years. The study was carried out on a sample of 240 schoolchildren in grades 10-11 and college students 1-2 years old. The methodology includes 27 statements. Its standardization was carried out in accordance with the necessary requirements for testing validity and reliability. Based on the results of exploratory factor analysis, 6 scales were identified that reflect the main components of responsibility: “Support”, “Self-control”, “Conscience”, “Social responsibility”, “Care for the environment”, “Avoidance of responsibility”. The scales have good internal consistency. Checking the convergent validity when comparing the general indicator of responsibility and the indicator of internality of the “Methods for diagnosing the level of subjective control” showed a significant correlation. The good psychometric indicators of the methodology and its portability allow us to recommend it for both individual and group work with adolescents.
Standardization of the "Perceptual modeling" Test for Children 5-6 and 6-7 Years old
Authors: Chumachenko D.V. , Yaglovskya E.K.
Published: October 2024

In modern sociocultural conditions, reliable diagnostic tools are needed to assess the mental development of a child, which would at the same time make it possible to adjust the objectives of educational work. The article reflects the results of adaptation and standardization of the "Perceptual modeling" test included in the diagnostic set for assessing the mental development of preschoolers (L.A. Wenger and colleagues). The study sample consisted of two groups: children 5-6 (N=1003) and children 6-7 (N=1516) years old. In these groups, children were offered various test options based on their age-related perceptual modeling capabilities. The adaptation of the "Perceptual modeling" test involved converting it into electronic form, changing the system for evaluating the results obtained and statistically verifying the possibility of using it in this form to solve diagnostic problems. The test standardization procedure has shown good external and internal validity, and its diagnostic reliability. Statistical analysis revealed the absence of significant gender differences in the performance of the test and the presence of significant differences between children with normal development and children with disabilities (speech, hearing impairment and mental retardation). As a result of standardization, age norms for mastering perceptual modeling actions for children with normal development and children with disabilities were determined by children of the sixth and seventh years of life.
Blood Glucocerebrosidase Activity and α-Synuclein Levels in Patients with GBA1-Associated Parkinson's Disease and Asymptomatic GBA1 Mutation Carriers
Authors: Emelyanov Anton K. , Usenko Tatiana S. , Kopytova Alena E. , Miliukhina Irina V. , Timofeeva Alla A. , Bezrukova Anastasia I. , Kulabukhova Darya G. , Baydakova Galina V. , Nikolaev Mikhail A. , Lavrinova Anna O. , Kudrevatykh Anastasia V. , Zhuravlev Alexander S. , Zakharova Ekaterina Yu. , Pchelina Sofya N.
Published: October 2024

Introduction. Mutations in a GBA1 gene, which encodes a lysosomal enzyme called glucocerebrosidase (GCase), are the most common genetic risk factor for Parkinson's disease (PD). The pathogenesis of PD results from the death of dopaminergic neurons in the substantia nigra of the brain, which is associated with the aggregation of α-synuclein protein. However, not all GBA1 mutation carriers develop PD during their lifetime.
The aim of this study was to evaluate GCase activity and α-synuclein levels in CD45+ blood cells of patients with PD associated with GBA1 mutations (GBА1-PD), asymptomatic carriers of GBA1 mutations (GBА1-carriers), and patients with sporadic PD (sPD), as well as correlation between the study parameters in the study groups.
Materials and methods. The study included patients with GBА1-PD (n = 25) and sPD (n = 147), and GBА1-carriers (n = 16). A control group included healthy volunteers (n = 154). The level of α-synuclein in CD45+ cells was measured by enzyme-linked immunosorbent assay, and GCase activity in dried blood spots was detected by high-performance liquid chromatography with tandem mass spectrometry.
Results. Increased level of α-synuclein protein was detected in CD45+ blood cells of patients with GBA1-PD, sPD, and GBA1-carriers compared to controls (p = 0.0043; p = 0.0002; p = 0.032, respectively). Decreased GCase activity was reported in GBA1-PD patients and GBA1-carriers compared to sPD patients (p = 0.0003; p = 0.003, respectively) and controls (p 0.0001; p 0.0001, respectively). However, negative correlation between α-synuclein levels and GCase activity was observed only in GBA1-PD patients, but not in GBA1-carriers.
Conclusion. Our data suggest a possible functional relationship between the activity of GCase and the metabolism of α-synuclein in PD associated with GBA1 mutations.
Evaluation of an Open Earthquake Early Warning System in Mexico, and Laboratory Tests of their Sensors
Authors: Kuna Vaclav , Ringler Adam T. , Melgar Diego
Published: October 2024

Microelectromechanical system (MEMS) accelerometers are useful for seismological and engineering applications because of their ability to record unsaturated large seismic signals. Recent advances in MEMS technologies enable the design of instruments with improved capabilities that also allow the recording of small signals. As a result, MEMS can be useful across a broad dynamic range and for both major earthquakes and smaller magnitude events. Here, we analyze the performance of a MEMS-based accelerometer with the capability of real-time data transmission. We discuss the self-noise level, dynamic range, and sensitivity, along with the timing precision and data transmission latency, and compare these parameters to other MEMS-based instruments. We also summarize observations from a regional network deployed in southern Mexico over a period of 3+ yr for the purpose of earthquake early warning. In addition to the sensor evaluation, we present a large, openly available data set of strong motion data from the Mexican network that comprises continuous ground-motion records from 24 accelerometers in the period between 2017 and 2022.
Bayesian Earthquake Forecasting Using Gaussian Process Modeling: GP-ETAS Applications
Authors: Molkenthin Christian , Zöller Gert , Hainzl Sebastian , Holschneider Matthias
Published: October 2024

Numerous seismicity models are known to simulate different observed characteristics of earthquake occurrence successfully. However, their ability of prospective forecasting future events is a priori not always known. The recently proposed semiparametric model, Gaussian process epidemic-type aftershock sequence (GP-ETAS) model, which combines the ETAS model with GP modeling of the background activity, has led to promising results when applied to synthetic seismicity. In this study, we focus on the ability of GP-ETAS for different forecasting experiments in two case studies: first, the Amatrice, Italy, sequence during 2016 and 2017, and second, long-term seismicity in Southern California. The results indicate that GP-ETAS performs well compared with selected benchmark models. The advantages become particularly visible in cases with sparse data, in which GP-ETAS shows in general a more robust behavior compared to other approaches.