bluuebunny/crossref_metadata_2025 huggingface dataset:
Institutional Entrepreneurship in Health Management: A Survey Experiment on Appreciative Inquiry®
Authors: Dempster Gregory , Kluver Jesse
Published: May 2019

Employing the lens of institutional entrepreneurship to help understand the logic of organizational change management, we conduct an analysis of the impact of Appreciative Inquiry® in a multi-unit division of a large, university-based health system. Our results indicate that, although there may have been some marginal impact in temporarily reducing an observed decline in employee commitment indicators, the program failed to sustain positive impacts over the longer term. Implications for the study of organizational change as the action of institutional entrepreneurs are briefly discussed.
Considerations Regarding the Relevance of Direct Foreign Investments in the Global Economy
Authors: Fraticiu Lucia
Published: May 2019

It is well known that the current business world, and also the investments, today are based on the global markets expansion. Contemporary reality shows us the image of a world which is irreversibly evolving towards the businesses globalization and the companies’ internationalization. The internal markets often become overcrowded, and the companies access more profoundly the global marketplace, which not only provides a place for all competitors, but also represents a source of new advantages for all. In the context of globalization the investment activity has gained new dimensions, becoming a global one, with serious implications, which manifest itself over the national economies and also over the world economy. Starting from these premises, the present paper’s purpose is to analyze a current, important and intensely debated issue, namely, the direct foreign investments, pointing out the main elements of their historic development and highlighting their fundamental role for the economic development of a country. Thus, here are reviewed some of the indisputable benefits of direct foreign investments generated within the country – as a dynamic development engine. Beyond the beneficial effects, which unequivocally denote the importance of drawing direct foreign investments, we try to answer the question “Can be identified negative effects of direct foreign investments which affect the receiving country?”
Time-Driven Activity-Based Costing Systems for Marketing Decisions
Authors: Park Yonpae , Jung Sungwoo , Jahmani Yousef
Published: May 2019

The activity-based costing (ABC) systems emerged as a management accounting innovation in the mid-1980s in response to dissatisfaction with traditional management accounting techniques and heightened international competition. Although ABC provides many advantages for managerial decision making, ABC tends to be outdated due to its limitations and is substituted by the time-driven activity-based costing (TDABC) systems. TDABC requires estimates of only two parameters: how much it costs per time unit of capacity to supply resources to activities and how much time it takes to perform each activity. TDABC allows incorporation of variation in the time demands made by different types of processes and consequently the representation of all possible combinations of activities that a process performs. This paper uses TDABC to calculate marketing costs and describes TDABC as a useful technique to reduce marketing resource costs and to support effective marketing decision making in various contexts such as marketing processes restructuring, marketing mix choices, customer profitability and price differentiation for customer classes.
Banks Digitalization - A Challenge for the Romanian Banking Sector
Authors: Sbarcea Ioana Raluca
Published: May 2019

The banking system has undergone several transformations since its beginning up to now, some as a result of adapting to customers’ requirements that have become increasingly sophisticated, and others as a result of the economic and political contexts that have passed, which again – have required its adaptation. Regardless of the situation, the banks have undergone a large digitization process, a process that is now in progress and which in the coming years can cause a significant change in the banking we knew about 10-15 years ago. Through this paper, I propose to analyse the situation of the banking system in terms of adapting to these challenges, at the level of Romania, in the context of the current situation at global and European level, in order to highlight both the progress achieved and the gap in comparison to the other countries, much more competitive from this perspective.
Moral Neutrality of Religion in the Light of Conflicts and Violence in Mediatized World
Authors: Szocik Konrad , Wisła-Płonka Joanna
Published: May 2019

Although only seven percent of wars in human history were caused by explicit religious motives– as it is suggested by one estimate – religious beliefs affect human attitude to the world. Especiallyin the context of the rash of contemporary conflicts and terror attacks which have a stated connec-tion to religious motives, it is important to try to understand the possible religious motivations ofsuch antisocial and dangerous behaviors. There are several different research perspectives on thistopic, but none of them by itself offers a sufficient explanation. The purpose of this essay is to showthat religious components themselves can be interpreted as morally neutral, and that their supposedimpact on behavioral patterns can, in fact, be attributed to non-religious factors. Religion is discussedas cultural phenomenon partially interacting with cognitive and adaptive patterns.
Polish School of the Literature of Fact: Characters of the Reportages as the Reflection of Reality
Authors: Golovko Khrystyna
Published: May 2019

The article analyzes the key feature of Polish school of the literature of fact, specifically the jour-nalistic work with the heroes of the materials that are the basis of the reportorial text. Peculiarities ofcharacters typical for Polish reportage are analyzed . Further, the article explores the specific featuresof communicative strategies of Polish reporters, reportorial technique. For a better understandingthe visual examples from reportorial text are provided.
Селекционная работа должна обеспечивать продовольственную безопасность с упреждением глобальных изменений климата
Authors: Драгавцев В.А.
Published: May 2019

Без аннотации
THE CONSTRUCTION OF EDITORIAL MORALITY IN THE CURRENT SITUATION IN VIETNAM
Authors: Dung Nguyen Duy
Published: May 2019

At any stage of history, the book is always considered an essential essence to mankind and human. The book is not only a tool but it also contains human values and ideas that support us to understand and access to the scientific progress of the world. To “get rid of” the good books, newspapers, magazines, the editors must firstly have the ability, the ability to exploit the manuscripts, they must always place social and cultural interests, the reader’s benefits on top. In particular, the element of honesty, objectivity is the important standard in the professional morality of the editors; particularly they must be respectful, wholeheartedly for the author, always protecting the interests of the author; the editors must always be aware of the need for life-long learning to enrich their minds and improving their personality
MANAGING INFORMATION TECHNOLOGY APPLICATION IN TEACHING AT HIGH SCHOOLS IN VINH YEN CITY, VINH PHUC PROVINCE MEETS INDUSTRIAL REVOLUTION 4.0
Authors: Thap Vu Kha
Published: May 2019

Entering the XXI century and especially in the period of the industrial revolution has entered the era of IT with the knowledge economy in the trend of globalization. The 4.0 mankind development of ICT, especially the Internet has had a strong impact and make changes to all activities profound social life of every country in the world. Through surveys in six high School, interviewed 85 managers and teachers on the status of the management of information technology application in teaching, author of the article used the SWOT method to distribute surface strength, weaknesses, opportunities and challenges from which to export 7 management measures consistent with reality. 7 measures have been conducting trials and the results showed that 07 measures of necessary and feasible.
SYSTEMATIZATION AND EVALUATION OF STATE MANAGEMENT MODEL AND SYSTEM FROM CENTRAL TO LOCAL ON ETHNIC AFFAIRS FROM 1986 TO PRESENT
Authors: Trung Tran , Thanh Minh Vu Thi
Published: May 2019

In recent years, there have been many scientific works in the country and abroad studying the model and the state management system of ethnic affairs; Content and mode of ethnic work. The works have provided scientific data as a basis for further research, development and improvement of the state management model of ethnic work in Vietnam. However, the researches also revealed certain limitations. These are the limitations and inadequacies in model research, state management system of ethnic affairs in new conditions; implementation of ethnic affairs in the locality; renovation of contents and mode in industrialization and modernization and actively integrating into the world. Therefore, in order to have sufficient scientific basis to propose the renovation of the model of state management on ethnic affairs, to renovate the content and mode of ethnic work, it is necessary to have scientific works to continue researching in the coming time.
Solutions to improve the efficiency of building a community-based model of new rural buiding in three extremely difficult communes under three poor districts (Program 30A) of the Northwest, the Central Highlands, the South West and expanding the model in the near future
Authors: Thanh Minh Vu Thi
Published: May 2019

The New Rural program in the whole country in general and in the Northwest, Central Highlands and the South West in particular has achieved many important results. In many localities, the community has actively participated in New Rural construction activities. Some localities have built a model of community organization - a typical model of New Rural development in ethnic minority areas. numbers in our country and are currently being widely scaled up by a number of localities. However, the process of constructing and implementing the pilot model alongside the advantages, is also posing many issues that need to be addressed. It is necessary to have solutions to improve the efficiency of the model, contributing to the successful construction of New Rural program in our country in general and in the North West, Central Highlands and West South in particular
ACHIEVEMENTS, LIMITATIONS AND SOME SOLUTIONS OF RESEARCHES ON ETHNIC POLICIES IN CENTRAL HIGHLANDS FROM 1986 TO PRESENT
Authors: Canh Trinh Quang , Huong Nguyen Thi
Published: May 2019

Being an important socio-economic region of Vietnam, Central Highlands plays a strategic role in national security, defense and has unique characteristics of natural conditions, population and ethnicity. With policies to develop socio-economy have been promulgated by Party and State, security, national defense and environment in Central Highlands have gradually developed. Studies on ethnic policies in Central Highlands; however, have a number of limitations: Common concept of policy has not been used; Some policies have not been studied or assessed; Strategic, long-term policies have not been paid attention; Researches to review the recommendations and solutions in scientific topics, projects on policy-making in Central Highlands have been missing.
REVIEWING THE HARMONIZATION OF COMPETENCY-BASED HIGHER EDUCATION IN SOUTH-EAST ASIA
Authors: Mar Ma Tin Cho
Published: May 2019

In our region, both technological development and international competition, basically from the industrial revolution, we grew to set our effort on education. Education system is an essential foundation to be successful in profession or trade and required to obtain a higher number of complex competencies than previously. This paper aim to discuss about the South-East Asia experience characteristic is connected with harmonized educational drive and the strategy of prioritizing goals in education and training which matched the stage of development.These experiences are related to the aspects highlighted by David Ashton and his colleagues in their study of education and training in East-Asia four tiger countries. Besides, the purpose of this paper Is to investigate the competency-based curriculum, learning needs and educational development based on competency in teacher training program.
ONLINE CLASSROOM MANAGEMENT - STRATEGIES AND LESSONS LEARNED
Authors: Cavanaugh Ph.D. Terence
Published: May 2019

Online courses typically take more time to teach than face-to-face courses, the demand on the instructor workload with regard to creating online content and administering online assessment. For example, studies have found that assessing online students can take two to five times the amount of time as comppared to face-to-face classes. Because of these time costs, it is important for online instructors to have a variety of strategies and tools to use to be more effective in managing their online classes as it relates to assessment (tests and projects), interactions, feedback, structure, and student presentations. This presentation will present on researched based strategies that have been found to be effective for managing the online class space
APPROACH TO THE SPACE MODEL FOR THE DEVELOPMENT OF BORDER-GATE ECONOMIC ZONE FOR POVERTY REDUCTION IN THE NORTHERN BORDER AREA
Authors: Cuong Phi Hung , Anh Vu Van
Published: May 2019

Paper contents is a part of a research project of the author B2015_TN_03_03 about market participation of ethnic minority households in border areas in the northeast Vietnam. Using sociological research in 1000 people are minority ethnic in the border province of North Eastern. Northeast border strip of Vietnam has special importance geo - political and geo - economic trade relations with China Southern region. Recognizing the importance of this, our State deployed model piloted border economic zones (BEZ) in the direction of openness and integration. So far, according to the joint assessment, the initial model BEZ bring positive results. It is time to evaluate, learn from experience in order to continue to improve and replicate the pilot model, access to the space model aimed at developing new markets border areas. To accomplish this goal, we think, to clarify a number of issues: (1) General understanding of the internal concept of BEZ, access market development model; (2) Evaluate BEZ in northeastern border on Vietnam as the new economic model; (3) Access to space development model in terms of market opening and integration of the border region of North Vietnam; (4) To propose some solutions for sustainable development space model developed markets northeastern border region of Vietnam.
PRESERVING AND PROMOTING LOCAL KNOWLEDGE IN ENVIRONMENTAL PROTECTION AND NATURAL RESOURCE EXPLOITATION AND USE OF ETHNIC MINORITIES IN THE NORTHERN MOUNTAINOUS REGION
Authors: Thanh Minh Vu Thi
Published: May 2019

Ethnic minorities in the Northern Mountainous Region not only use the application of scientific-technological advances but also experiences of the community to enhance production efficiency and environmental protection. Local knowledge (TTDP) of ethnic minorities is useful for environmental protection and natural resource exploitation & use. These are environmental & weather knowledge; farming experiences on sloping and forestry land; knowledge about environmental protection and natural resource exploitation & use especially how to protect precious resources by specific rules/regulations of customary law. In the context of declining natural resources, TTDP is eroded, captured, or illegally exploited. There should be measures in order to preserve and promote TTDP as well as raise the awareness of the community about its important role.
Learn from the Past, Prepare for the Future: Impacts of Education and Experience on Disaster Preparedness in the Philippines and Thailand
Authors: Hoffmann Roman , Muttarak Raya
Published: May 2019

This study aims at understanding the role of education in promoting disaster preparedness. Strengthening resilience to climate-related hazards is an urgent target of Goal 13 of the Sustainable Development Goals. Preparing for a disaster such as stockpiling of emergency supplies or having a family evacuation plan can substantially minimize loss and damages from natural hazards. However, the levels of household disaster preparedness are often low even in disaster-prone areas. Focusing on determinants of personal disaster preparedness, this paper investigates: (1) pathways through which education enhances preparedness; and (2) the interplay between education and experience in shaping preparedness actions. Data analysis is based on face-to-face surveys of adults aged ≥15 years in Thailand (N = 1,310) and the Philippines (N = 889, female only). Controlling for socio-demographic and contextual characteristics, we find that formal education raises the propensity to prepare against disasters. Using the KHB method to further decompose the education effects, we find that the effect of education on disaster preparedness is mainly mediated through social capital and disaster risk perception in Thailand whereas there is no evidence that education is mediated through observable channels in the Philippines.
Building pilot model of community organizing for new rural construction in the extremely difficult communes in poor districts of the North West, Central Highlands and South West - Results and issues
Authors: Son Ngo Quang
Published: May 2019

The author of this paper has studied the situation of constructing pilot model of community organization of new rural construction in three extremely difficult communes in three poor districts (Program 30a) in the North West, Central Highlands and South West, depth analysis of the results, assessment of the advantages and problems of building the model of social management organization (Internalunity Development Board, Club of Information, Education and Communication, Green CleanBeautiful-Safety-Friendly Environment Board, Community Convention Development Board) and the model of organization of production management is suitable with the economic, cultural and social conditions of each locality, is suitable with the customs and habits of each ethnic minorities group (Production of hybrid rice with high yield and economic efficiency, Growing coffee and growing coffee grafted with butter, Rice with fish intercropping). Since then, the author proposed groups of solutions to improve the efficiency of implementing the pilot model of community building in new rural areas in three extremely difficult communes in three poor districts (Program 30A) in three areas of North West, The Central Highlands, the South West in the direction of sustainable development and the replication of the model into the provinces in the coming time.
Optimalisasi Kinerja Terminal Dengan Menggunakan Metode Penilaian Tingkat Kepentingan Dan Kepuasan Pengguna Terminal (Studi Kasus Terminal Poris Pelawad Kota Tangerang)
Authors: Muhammadun Haris
Published: May 2019

Terminal is the place for drop off and pick up of the people and transfer mode to next journey according trip end destination. The facility of terminal divided of vehicle facility, people facility, and operation facility. This facilities must be good performance, so can service the customer. But tf1e terminals officer, must be evaluation the facility conditions periodically. Importancei1erformance analysis method can be use, with interview the customer of terminal. Base on data from interview, percentage of importance level and satisfaction level can be measure. From this prercentage, problematic mapping shown for decided problem solving performance of terminal
â€œDecolonise, Donâ€™t Diversifyâ€: Discounting Diversity in the South African Academe as a Tool for Ideological Pacification
Authors: Makhubela Malose
Published: May 2019

The problem of the South African university, and society in the same breath, is not so much that of governance or politics but ideology. The deepening realisation of the farcicality and impossibility of strategies, attendant ideologies and â€œmaster signifiersâ€ of transformation (such as diversity, multiculturalism and rainbow nation) of the South African society and (whatever remains of) its institutions has never been more acute than now, when the insistence at meaningful change and the unanimous rejection, mostly by blacks, of the university (at least in its current form) have gained traction. This paper draws on Å½iÅ¾ekâ€™s Lacanian theory of ideology to provide a counter-narrative and reading of official transformation consensus and ideologies like diversity, by highlighting their ethical liminalities. The underside of diversityâ€™s official claims to equality and justice are unmasked, and the terror and ironies of this liberal ideology are exposed, especially its refusal to recognise that whiteness (as a system) and justice can never coexist or inhabit the same space. Transformation discourse, of our kind, fashioned under diversityâ€™s register can never escape being appropriated by liberal ideology and practice, as yet another means to reaffirm its priorities.
Advancing Professional Teaching in South Africa: Lessons Learnt from Policy Frameworks That Have Regulated Teachersâ€™ Work
Authors: Kimathi Faith , Rusznyak Lee
Published: May 2019

Teaching and teacher education in South Africa have emerged from a highly fragmented past. Teachers from diverse backgrounds, experiences and qualifications find themselves working together in schools where they do not necessarily have access to a common language of practice, nor a shared understanding of professional teaching practices. To address these challenges, the South African Council of Educators (SACE) has developed a set of professional teaching standards for use in the South African context. This is not the first time a policy framework has tried to articulate and direct teachersâ€™ work. This paper analyses four other frameworks that have been used to regulate, monitor and evaluate the work of South African teachers over the past two decades. These other frameworks are The Roles of the Educator and Their Associated Competences, the SACE Code of Professional Ethics, the Integrated Quality Management System (IQMS) and the Basic Competences of a Beginner Teacher. Our analysis shows how these frameworks present teaching in ways that constrain teacher professionalism in some ways. They address some aspects of professional teaching while ignoring others. In particular, none of them adequately acknowledge the relations between knowledge, skills, judgement and the ethical orientations that underpin professional teaching. The ways in which previous frameworks have constrained teacher professionalism has important implications for SACE if its set of professional teaching standards is to more successfully enhance teacher professionalism in the South African context.
Dynamics of Decoloniality in South Africa: A Critique of the History of Swiss Mission Education for Indigenous People
Authors: Seroto Johannes
Published: May 2019

This paper presents a new framework to analyse missionary education in South Africa, using Grosfoguelâ€™s conceptual and methodological lens of coloniality of power, coloniality of knowledge, and coloniality of being. Firstly, the paper introduces the theoretical lens that undergirds this study and describes the three above-mentioned dimensions. Rather than seek generalisations concerning missionary education in the historical record, the paper presents an analysis of the endeavours of the Swiss Mission Society as an example of Protestant evangelism in South Africa. I indicate how the Swiss Mission used education to racialise and hierarchise the indigenous people and how, in this process, knowledge and indigenous people were dehumanised. The argument is based on examples drawn from the Swiss Missionâ€™s teacher training institution, namely the Lemana Teachersâ€™ Training College, near Elim. Based on the paperâ€™s critical analysis, I propose how power structures, colonised knowledge systems and beings could be decolonised.
A Historical Perspective on AA Boesak as Organic Intellectual Par Excellence: On Social-analytical and Hermeneutic Mediation in Theology
Authors: Botha Nico
Published: May 2019

Allan Aubrey Boesak hasâ€”over the past five years or soâ€”been honoured from diverse perspectives by South Africans in festschrifts and journal articles, and particularly in a thesis. One would, however, look in vain for a study on his prowess as an organic intellectual. The objective of this article is to offer a historical perspective on his legacy of embodying, in an integrated fashion, the connectedness of the life of the mind and the struggles of the poor and the oppressed. His legacy is assessed in terms of the first three steps of the praxis cycle, namely insertion, context analysis, and theological reflection. The article shows that based on his rootedness in the black church, the Belydende Kring, the Alliance of Black Reformed Churches in Southern Africa and the United Democratic Front, he emerged as an organic intellectual par excellence. In accentuating his theological legacy, issues like identifying God as the God of the oppressed, human rights, and justice are highlighted. The article concludes with a brief attempt at capturing Boesakâ€™s intellectual legacy
Theological Impediments to Inculturation of the Eucharistic Symbols in the Anglican Church of Kenya
Authors: Kiarie George Kuria
Published: May 2019

Inculturation of the Eucharistic symbols has been highly advocated in the mission-based churches located in the global South. In spite of this discourse being so fundamental for the expansion of Christian faith in any ecclesiastical context, there are emerging issues silencing this clamour. It is against this background that this article is set in order to explore the theological impediments to inculturation of the Eucharistic symbols in the Anglican Church of Kenya (ACK), with special reference to the diocese of Thika.
The Bells of the Stellenbosch Moederkerk
Authors: De Wet Tertius , Teugels Jef L. , Van Deventer Pieta
Published: May 2019

The Dutch Reformed Moederkerk of Stellenbosch has a long history, being the second oldest congregation of the Dutch Reformed Church in South Africa. The history of the church has been well documented, including the architecture and building of the church buildings over its 332 years of existence. However, although bells have from the beginning played an important part in the churchâ€™s history, very little has been written on the bells. This paper reports on research carried out into that important aspect of the churchâ€™s life, in that way adding to Moederkerkâ€™s recorded history.
Beyond Mount Kenya Region: 40 Years of Theological and Practical Education at St Andrew’s College, Kabare (1977- 2017), Julius Gathogo
Authors: Njogu Geoffrey Karimi
Published: May 2019

Book review
Faces of Religious Healing in Nkhoma, Malawi: An Exercise in Oral History
Authors: Landman Christina
Published: May 2019

On 10 November 2016, the Nkhuni Centre for Oral History was established as part of the Nkhoma Museum at the University of Nkhoma in Malawi. Consequently, the author conducted an oral history project in and around the town of Nkhoma to strengthen the capacity of the centre to engage in future projects. The aim of the research was to recordâ€”albeit in restricted numbersâ€”the answers which people living in the villages around Nkhoma, as well as patients in Nkhoma Hospital, gave to the interview questions: â€œWhat/who makes you ill?â€ and â€œWhat/who makes you healthy?â€ Furthermore, the research was to establish the religious ways of healing acknowledged by the interviewees. Finally, the research sought to inform itself on the historyâ€”short as it may beâ€”of how and why interviewees have chosen to change from one church to the other, or remain in a specific church, in order to find their preferred way of religious healing. The aim of the article is to present the research results with a focus on the methodological steps taken in doing oral history research.
ANALYSIS OF CLINICAL DIAGNOSES IN FATAL HEAD INJURY CASES
Authors: Klevno Vladimir A. , Maksimov Alexander V.
Published: May 2019

Aim. In this research, we compare the antemortem and postmortem diagnosis in fatal head injury cases with the purpose of establishing the structure and causes of incorrect diagnoses.

Material and methods. 1223 cases of fatal outcomes with the clinical diagnosis of death from head trauma were examined. In each case, we carried out a comparison of the clinical and autopsy diagnosis in terms of all report headings in order to establish reasons for divergence in the antemortem and postmortem diagnoses and the role of incorrect clinical diagnostics in the onset of death.

Results. In 35% of cases, the clinical head trauma diagnoses were incorrectly categorized. In 22.6% cases, the antemortem diagnoses were formulated not in correspondence with the modern classifi cation and terms of ICD-10. In 11.7% cases, the violation of the etiopathogenesis principle was observed. Clinical diagnoses were not supported by objective data and examination results in 4.5% cases. The discrepancy between the clinical and autopsy diagnoses in terms of the ‘underlying disease’, ‘complications’ and ‘concomitant’ headings was 15.6%, 10.1% and 14.0% from all the studied cases, respectively. Subjective reasons are found to statistically predominate among the identifi ed reasons for the divergence of diagnoses.

Conclusion. It is established that fi nal clinical diagnoses in fatal head injury cases fail to fully meet the criteria of structure, nosology, etiopathogenesis and reliability. Erroneous diagnoses are found to result from underestimation of clinical data, insuffi cient observation and instrumental examination of patients, incorrect formulation of the fi nal clinical diagnosis.
Sexualidade na terceira idade: a visão dos idosos de um município do interior do estado de São Paulo
Authors: Silva Luiz Fernando de Andrade , Pinto Adriana Avanzi Marques
Published: May 2019

Objetivo: Pretende-se com esse estudo descrever o perfil de vida e sexual dos idosos, de um município do interior paulista e analisar seu conhecimento sobre sexualidade. Métodos: Foi aplicado um questionário já validado pelo Laboratório de Gênero, Sexualidade e Corporeidade (LAGESC/UDESC), composto por 7 perguntas. Para as perguntas de número 1, 2, 5 e 7 foi utilizado uma escala com variação de 0 a 10, que corresponde a nada (0), pouco (1 a 3), medianamente (4 a 6), razoavelmente (7 a 9) e muito (10). Resultados: Participaram do estudo 49 idosos que ao serem questionados sobre a importância do sexo na juventude, 33% disseram ser razoavelmente importante e 53% muito importante. Em relação a frequência sexual atual 44% dos entrevistados responderam 1 vez por semana. Conclusão: O fator frequência sexual acaba não sendo o principal para satisfação, pois os idosos falam muito sobre carinho, companheirismo e atenção. Vale ressaltar a importância da sexualidade para eles e a importância da melhora da abordagem pelos profissionais de saúde.
Development and Validation of the QUBE Protein Force Field
Authors: Allen Alice , Robertson Michael J. , Payne Michael C. , Cole Daniel
Published: May 2019

Molecular mechanics force field parameters for macromolecules, such as proteins, are traditionally fit to reproduce experimental properties of small molecules, and thus they neglect system-specific polarization. In this paper, we introduce a complete protein force field that is designed to be compatible with the QUantum mechanical BEspoke (QUBE) force field by deriving non-bonded parameters directly from the electron density of the specific protein under study. The main backbone and sidechain protein torsional parameters are re-derived in this work by fitting to quantum mechanical dihedral scans for compatibility with QUBE non-bonded parameters. Software is provided for the preparation of QUBE input files. The accuracy of the new force field, and the derived torsional parameters, are tested by comparing the conformational preferences of a range of peptides and proteins with experimental measurements. Accurate backbone and sidechain conformations are obtained in molecular dynamics simulations of dipeptides, with NMR J coupling errors comparable to the widely-used OPLS force field. In simulations of five folded proteins, the secondary structure is generally retained and the NMR J coupling errors are similar to standard transferable force fields, although some loss of the experimental structure is observed in certain regions of the proteins. With several avenues for further development, the use of system-specific non-bonded force field parameters is a promising approach for next-generation simulations of biological molecules.
Debiasing Algorithms for Protein Ligand Binding Data do not Improve Generalisation
Authors: Sundar Vikram , Colwell Lucy
Published: May 2019

The structured nature of chemical data means machine learning models trained to predict protein-ligand binding risk overfitting the data, impairing their ability to generalise and make accurate predictions for novel candidate ligands. To address this limitation, data debiasing algorithms systematically partition the data to reduce bias. When models are trained using debiased data splits, the reward for simply memorising the training data is reduced, suggesting that the ability of the model to make accurate predictions for novel candidate ligands will improve. To test this hypothesis, we use distance-based data splits to measure how well a model can generalise. We first confirm that models perform better for randomly split held-out sets than for distant held-out sets. We then debias the data and find, surprisingly, that debiasing typically reduces the ability of models to make accurate predictions for distant held-out test sets. These results suggest that debiasing reduces the information available to a model, impairing its ability to generalise.
Desulfonylative Arylation of Redox-Active Alkyl Sulfones with Aryl Bromides
Authors: Hughes Jonathan , Fier Patrick
Published: May 2019

Herein we describe the development of the first reductive cross-electrophile coupling between alkyl sulfones and aryl bromides. The use of alkyl sulfones as coupling partners offers strategic advantages over other alkyl electrophiles used in reductive coupling reactions, as the sulfone moiety can be incorporated into molecules in unique ways and permits α-functionalization prior to coupling. The conditions developed here can be applied to incorporate a wide array of aromatic rings onto (fluoro)alkyl scaffolds with broad functional group tolerance and generality, making this a practical method for late-stage diversification.
Band Gap Modulation in Zirconium-Based Metal-Organic Frameworks by Defect Engineering
Authors: Taddei Marco , Schukraft Giulia M. , Warwick Michael E. A. , Tiana Davide , McPherson Matthew , Jones Daniel R. , Petit Camille
Published: May 2019

We report a defect-engineering approach to modulate the band gap of zirconium-based metal-organic framework UiO-66, enabled by grafting of a range of amino-functionalised benzoic acids at defective sites. Defect engineered MOFs were obtained by both post-synthetic exchange and modulated synthesis, featuring band gap in the 4.1-3.3 eV range. Ab-initio calculations suggest that shrinking of the band gap is mainly due to an upward shift of the valence band energy, as a result of the presence of light-absorbing monocarboxylates. The photocatalytic properties of defect-engineered MOFs towards CO2 reduction to CO in the gas phase and degradation of Rhodamine B in water were tested, observing improved activity in both cases, in comparison to a defective UiO-66 bearing formic acid as the defect-compensating species.
THREE STRATEGIES OF PROFILING EVENTS IN CAUSATIVE CONSTRUCTION WITH PREFIX PA- IN DHAO
Authors: Balukh Jermy Imanuel
Published: May 2019

This paper investigates causative constructions in Dhao, which involves the prefix pa-. Dhao is a language spoken by about 3000 people on Ndao Island, Eastern Indonesia. The use of pa- results in three different constructions. First, a construction with a single verbal predicate in which pa- is fused with the base verb expressing the cause and caused events. Second, the pa-derived verb requires a lexical verb to precede it resulting in an SVC. Thus, the events profiled are arranged into separate components. Third, the construction is periphrastic, where the pa-derived verb appears in the subordinate clause designating result state of the causee, while the causation is expressed by a lexical verb in the main clause. These three different strategies are employed to express different events profiled in the causativized construction.
Talking Donald Trump: A Sociolinguistic Study of Style, Metadiscourse, and Political Identity
Authors: Denistia Karlina
Published: May 2019

ISBN                : 978-1-138-24450-4 (hbk)ISBN                : 978-1-3152-7688-5 (ebk)Penulis             : Jennifer SclafaniPenerbit           : Routledge (2018)Tebal               : 105 halaman
EFEKTIFITAS RELAKSASI AUTOGENIK & AKUPRESUR MENURUNKAN SAKIT KEPALA & TEKANAN DARAH PADA LANSIA HIPERTENSI DI DAERAH RAWAN BENCANA MERAPI
Authors: Priyo . , Margono . , Hidayah Nurul
Published: May 2019

Merapi merupakan gunung api yang mempunyai daya rusak tinggi, paling aktif dan  terganas di Indonesia. Peristiwa erupsi merapi tahun 2010  masih menimbulkan trauma pasca bencana pada sebagian lansia sampai dengan sekarang. Dampak psikologis ini memicu semakin meningkatnya penyakit  hipertensi di masyarakat terutama pada lansia. Penderita hipertensi biasanya mengeluh sakit kepala dan  tekanan darahnya meningkat.  Terapi  secara aman, mudah  dan minimal efek sampingnya  yaitu dengan menggunakan relaksasi autogenik dan terapi akupresur. Penelitian ini menggunakan rancangan  quasy experiment dengan  rancangan  two group pre-post test design.  Jumlah sampel sebanyak 40 responden. Perlakuan  dilakukan selama 2 kali perminggu selama 3 minggu. Hasil penelitian menunjukkan adanya penurunan tekanan darah maupun nyeri pada klien lansia hipertensi baik  dengan relaksasi autogenik maupun akupresur. Hasil analisis uji T dependent diperoleh hasil tekanan sistolik (P^ 0,00 ) dan diastolik (P^ 0,00), setelah diintervensi relaksasi autogenik dan  tekanan sistolik (P^ 0,00 ) dan diastolik (P^ 0,01) setelah diintervensi akupresur. Artinya ada perbedaan tekanan darah sistolik maupun diastolik setelah dilakukan intervensi relaksasi autogenik maupun akupresur. Sedangkan hasil uji T independent  diperoleh hasil 0,316, artinya bahwa tidak terdapat perbedaan antara teknik relaksasi dan teknik akupresur. Tenaga kesehatan terutama perawat diharapkan dapat menjadikan relaksasi autogenik maupun akupresur sebagai terapi alternatif pada hipertensi.
Analysis of MSME Actors’ Behavior in Preparing Financial Statements With Modified Theory of Planned Behavior
Authors: Maharani Husnunnida
Published: May 2019

This research aimed to examine factors that can increase the MSME actors’ interest in preparing financial statements dan relate this interest to the MSME actors’ actual behavior of preparing financial statements. This research modified the Theory of Planned Behavior (TPB)  by adding ‘self-efficacy’ construct. This research employed a survey method by using questionnaires to collect the data from the research samples of MSME actors assisted by PT. Semen Indonesia (Persero) Tbk. The samples selected were those who had prepared financial statements, amounted to 100 respondents. Moreover, the researcher used a Partial Least Square (PLS) in the data analysis. The results showed that ‘interest’ construct positively affected the MSME actors’ behavior of preparing financial statements. Attitudes, subjective norms, behavioral control, and self- efficacy also had a positive effect on the MSME actors’ interest in preparing financial statements. The implications of the results of this research can be used as evaluation materials by the Partnership and Environmental Development Programs of PT. Semen Indonesia (Persero) Tbk. to create more MSME actors with the capability of preparing financial statements. This capability can facilitate the process of monitoring and evaluating the performance of MSMEs by providing the required factors through training and development programs.
The Investigation of Taxpayer Compliance in Tax Amnesty
Authors: Diamastuti Erlina , Hardanti Kurniasari Novi
Published: May 2019

This study aims to interpret tax payer behavior in the implementation of tax amnesty with qualitative approach. The main data sources were 8 informants. The informant is a taxpayer both business and personal entity in Surabaya who have implemented the tax amnesty program in phase I and II, which starts in July 2016 until December 2016. The results of this study, first few informants disobedient in taxation liability. Second, tax amnesty has not made taxpayer obey yet. The conclusion is tax Amnesty is not a choice but a compulsion.
Сучасний стан судово-психіатричної експертизи та надання психіатричної допомоги особам із станами залежності від психоактивних речовин, які скоїли кримінальні правопорушення
Authors: Oliinyk Oksana , Revenok Oleksandr
Published: May 2019

Анотація

Актуальність. Неухильно зростаючі показники поширеності психічних розладів внаслідок різних форм залежностей та висока криміногенність таких осіб обумовили низку законодавчих змін у сфері юриспруденції (права), медицини та експертизи.

Мета - проаналізувати та науково обґрунтувати актуальність законодавчих змін щодо судово-психіатричної експертизи та надання психіатричної допомоги особам із станами залежності від психоактивних речовин, які вчинили кримінальні правопорушення.

Матеріали та методи. Для наукового обґрунтування використовувались результати судово-психіатричного обстеження 368 підекспертних із залежністю від ПАР. Вибірка була представлена групою з алкогольною (АЗ) та наркотичною залежністю (НЗ) (відповідно 156 і 212 випадків). Для аналізу і обробки даних застосовувались аналітичний, клініко-анамнестичний, клініко-психопатологічний, статистичний методи і метод судово-психіатричного аналізу.

Результати наукових досліджень свідчать про високі показники наркозахворюваності та рецидивності злочинів, велику частку наркозалежних осіб в установах відбування покарань внаслідок низького порогу притягнення їх до кримінальної відповідальності. Це демонструє неефективність жорстких кримінальних підходів стосовно осіб, залежних від ПАР і свідчить про необхідність гуманізації державної політики щодо них.

Висновки. Законодавство України потребує нагальних змін у питаннях запровадження альтернативних покаранню заходів лікування осіб із станами залежності, формування мережі спеціалізованих медико-реабілітаційних центрів, впровадження диференційованих експертних підходів при виборі медичних заходів примусового чи альтернативного характеру.

Судово-психіатрична експертиза виступає першим етапом практичної реалізації задекларованих законодавчих змін. Однак, з урахуванням сьогоденних реалій, самі експерти потребують соціальних гарантій своєї професійної незалежності.
Оцінка якості життя та психологічного стану у пацієнтів з неалкогольною жировою хворобою печінки та надмірною вагою
Authors: Baka Olena , Skurat Kateryna , Frankova Iryna , Potapov Oleksij , Perehrestenko Oleksandr , Man'kovs'kyj Borys , Todurov Ivan
Published: May 2019

Актуальність. Найбільш поширеним захворюванням печінки в світі в останні роки вважається неалкогольна жирова хвороба печінки (НАЖХП). Враховуючи те, що це захворювання тісно пов’язано з метаболічними порушеннями і, в першу чергу, з ожирінням, це значно погіршує якість життя пацієнтів, а також може супроводжуватись депресивними розладами.

Мета. З метою оптимізації лікування, проаналізувати та визначити оптимальні опитувальники для оцінки якості життя, скринінгу та оцінки ступеня тяжкості депресивних розладів у пацієнтів з НАЖХП та ожирінням з різним рівнем тяжкості захворювання.

Матеріали та методи. Було проаналізовано публікацій̈ в таких бібліографічних базах даних, як: Pubmed та Google Scholar за ключовими словами: депресивний розлад, депресія, якість життя, неалкогольна жирова хвороба печінки, ожиріння.

Результати.  Основні методики оцінки якості життя (ЯЖ) та депресивних станів у пацієнтів з НАЖХП та  ожирінням – опитувальники. В ході аналізу літератури за темою виявлено, що найбільш зручними для оцінки ЯЖ в клінічній практиці є спеціальні опитувальники Chronic Liver Disease Questionnaire (CLDQ) та Liver Disease Symptom Index 2.0 (LDSI 2.0), а для оцінки наявності симптомів депресії - шкала депресії Бека (Beck Depression Inventory, BDI).

Висновки. Оцінка ЯЖ та скринінг депресивних розладів у пацієнтів з НАЖХП та ожирінням має велике значення для прогнозування ефективності терапії, вибору тактики лікування.
Ґендерні особливості вживання алкоголю зі шкідливими наслідками при психічній та соматичній патології в практиці сімейної медицини
Authors: Salden' Viktorija
Published: May 2019

Даний текст є тезами Науково-практичної конференції «Психосоматична медицина: наука і практика». Описане нижче присвячено ґендерним особливостям вживання алкоголю зі шкідливими наслідками при психічній та соматичній патології в практиці сімейної медицини.
Когнітивні та поведінкові порушення у дітей з вродженою гідроцефалією
Authors: Makarenko Svitlana
Published: May 2019

Даний текст є тезами Науково-практичної конференції «Психосоматична медицина: наука і практика». Описане нижче присвячено когнітивним та поведінковим порушенням у дітей з вродженою гідроцефалією.
Клінічні особливості динаміки соматизованого розладу та механізми соматизації
Authors: Mamchur Alexander , Yuryeva Lyudmila
Published: May 2019

Ця публікація є фрагментом роботи з аналізу клініко-психопатологічних особливостей соматоформних порушень у хворих із психотичними та непсихотичними розладами задля обґрунтування шляхів оптимізації діагностики соматоформних порушень у хворих на психічні розлади різного генезу з урахуванням патогенетичних механізмів соматизації та розробки комплексних лікувально-реабілітаційних заходів.
pH-RESPONSIVE CARBOXYMETHYL CELLULOSE CONJUGATED SUPERPARAMAGNETIC IRON OXIDE NANOCARRIERS
Authors: DEMİREL TOPEL Seda , GÜRKAN POLAT Tulin
Published: May 2019

In the present study, polyethyleneimine (PEI) coated superparamagnetic iron oxide nanoparticles (SPIONs) having the size of 15 nm in diameter with high magnetic saturation (60 emu/g) have been prepared by co-precipitation method. The synthesized PEI-Fe3O4 nanoparticles have been fully characterized by transmission electron microscope (TEM), dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD) techniques. The free amine groups on the PEI-Fe3O4 surface has been covalently functionalized with carboxymethyl cellulose (CMC) by the catalysis of N,N'-Dicyclohexylcarbodiimide (DCC) and N, N'-Dimethylpyridin-4-amine (DMAP) coupling to produce CMC-Fe3O4 nanocarriers. The prepared CMC-Fe3O4 nanocarriers have been loaded with a well-known anti-tumor drug doxorubicin (Dox) and investigated its loading and releasing profiles from the nanocarrier. The CMC acted as an excellent nanocarrier for Dox with a loading efficiency ≈ 86%. The drug releasing profile has been studied at different pH values (3.5; 5.5; and 7.4). When the pH of the release medium (phosphate buffer solution) was changed from 7.4 to 5.5 or 3.6, the drug release has been increased which indicates that the drug releasing is pH dependent.