bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the Cultivation of Pangerten and Gotong Royong Character Values Through Social Learning for Blind Students at SLB A YKAB Surakarta
Authors: Hasri Isnanto Irham , Atik Catur Budiati  , Yosafat Hermawan Trinugraha
Published: August 2024

The unfocused cultivation of character values in the learning process is a problem in the field of education that can result in a lack of affective and pyschomotor aspects for students. Moreover, the lack of opportunities for the cultivation of character values is currently also affected to students with special needs, one of which is blind in SLB A YKAB Surakarta. Character problems are shown in the limited social skills of blind students who seem to still be independent (individualist) when interacting with others in SLB. Therefore, a good solution step is needed to help blind students fix the problem and grow their social skills through the process of instilling the character values of gotong royong and pangerten. This study aims to examine the extent to which blind students apply the cultivation of the character values of gotong royong and pangerten utilizing the stages of Bandura's social learning theory in the learning activities of SLB A YKAB Surakarta. The method used is qualitative with phenomenological approach. The research data sources were obtained from 6 informants, namely 2 teachers, 2 blind students, and 2 parents of students as research subjects. The results showed that blind students have implemented the process of instilling character values according to the stages of social learning. This is evidenced by the results of the actualization of students who have been able to bring up the attitude of togetherness as a reflection of the orientation of gotong royong and pangerten.
Implementation of Grapyak Semanak Culture-Based Character Strengthening in the Prevention of Psychic Violence among Blind Students (Thomas Lickona's Character Education Perspective)
Authors: Indonesia Alvin Rajaswara , Septina Galih Pudyastuti  , Yosafat Hermawan Trinugraha
Published: August 2024

Psychological violence between students is a problem in the world of education and can occur between blind students in special schools. This study aims to explore the strategies, inhibiting factors, and implications of character strengthening based on grapyak semanak culture in preventing psychological violence between blind students at SLB A YKAB Surakarta. The informants involved in this study include three teachers of blind students and seven blind students of grade VI SDLB. Data collection was conducted through participant observation, semi-structured interviews, and documentation. The collected data were analyzed using an interactive model with the stages of data reduction, data presentation, and conclusion drawing. The results showed: 1) character strengthening based on grapyak semanak culture in the prevention of psychological violence among blind students at SLB A YKAB Surakarta is implemented by teachers through storytelling strategies and guidance and counseling; 2) inhibiting factors for strengthening grapyak semanak culture-based character in the prevention of psychological violence among blind students at SLB A YKAB Surakarta include the difficulty of blind students in regulating negative emotions and less than optimal synergy between parents and teachers of blind students; 3) Teachers' strategies in strengthening character based on grapyak semanak culture can have constructive-progressive implications for the majority of aspects in the grapyak semanak character component of visually impaired students, but not for aspects of moral awareness, self-control, and habits.
Hambatan Serta Dampak Pelaksanaan Profil Pelajar Pancasila Dimensi Bernalar Kritis Dalam Proses Pembelajaran Sejarah Di Kelas X SMA Negeri 1 Banjarmasin
Authors: Anggelika Permata Sari  , Rochgiyanti  , Heri Susanto
Published: August 2024

The critical reasoning dimension of students in history learning is quite low, causing a lack of ability in solving problems, lack of curiosity, and learning that is still monotonous makes students lazy and bored in the learning process. To overcome this problem, one of them is done through the Pancasila student profile, by applying 6 dimensions. The purpose of this study was to analyze the obstacles and impacts of the Pancasila student profile of the critical reasoning dimension on the history learning process in class X of SMA Negeri 1 Banjarmasin. This study used a qualitative method. The subjects of the study were 35 students of class X-5 of SMA Negeri 1 Banjarmasin using a questionnaire and 5 students in-depth interviews, 1 history subject teacher, and a curriculum representative. Data obtained through observation of teacher activities, student activities, critical reasoning skills and student motivation in the learning process. Data analysis techniques in this study were the implementation of learning and evaluation. In the application of the Pancasila student profile, the critical reasoning dimension has obstacles, namely internal and instrumental factors, as well as negative and positive impacts. The conclusion of the study was several obstacles and impacts that occurred in the learning process, but could still be overcome by schools and teachers. Suggestions for school principals, teachers, and other researchers are that this research can be used as an option in implementing the Pancasila student profile in the critical reasoning dimension in the history learning process.
Peran Perpustakaan dalam Pelestarian Budaya Lokal di Dinas Perpustakaan dan Kearsipan Kabupaten Pakpak Bharat
Authors: Manik Vera Sriyuni , Siregar Yusra Dewi
Published: August 2024

Indonesia is a country of cultural diversity from Sabang to Merauke. The role of libraries has great significance as an effort to preserve and maintain these cultural values. Libraries as information centers also have a function as cultural preservation. However, besides that we need to explore what role the library plays in preserving local culture. This research aims to find out how the role of libraries in preserving local culture. This research uses qualitative methods with direct observation and interviews with librarians. Libraries have a very important role in preserving local culture in Pakpak Bharat Regency. Pakpak people in general also have a greeting pattern or pertuturen where someone will call their relatives with a distinctive and polite greeting and have a function for each term of greeting. Through its programs, the library is able to become an effective agent in documenting, promoting, and introducing cultural heritage to the community.
Protection of Women’s Rights in the Escalating Conflict in Palestine
Authors: Nidatya Nurfarah , Darmastuti Shanti , Saraswati Dini Putri
Published: August 2024

The Israeli-Palestinian conflict is inextricably linked to the issues Palestinian women face. They have been affected psychologically, mentally, and physically. The Palestinian independence movement and Palestinian women's struggle are inextricably linked. The protection of women's rights has grown in importance in light of the protracted conflict in Palestine. Conflict-related tensions and economic pressures are contributing to an increase in domestic violence. In conflict areas, fundamental rights like freedom of speech, travel, and political participation are often ignored or restricted. This study investigates how both governmental and non-governmental entities safeguard women's rights in Palestine. This qualitative case study-based research examines how women's rights were maintained in Palestine as the conflict escalated. This study examines the dynamics of women's rights issues in Palestine and the difficulties in addressing these issues in-depth using secondary data from earlier studies, journal articles, and online articles. The study concludes that a multifaceted approach is necessary to protect women's rights in Palestine, given the Israeli occupation and patriarchal norms. Cooperation is required to defend women's rights and promote a more equitable society in Palestine.
Preventing Digital Sexual Harassment: Strategies for Improving Digital Literacy An Islamic Education Perspective
Authors: Eka rizky bastian  , Muhammad Thohir
Published: August 2024

Digital harassment is becoming increasingly widespread and has become a serious problem in the digital era, including among society, especially Indonesian society. harassment itself definitely has an impact on the victim, and it definitely has a bad and negative impact, both physically and mentally. Islamic education plays an important role which is expected to prevent digital harassment by instilling moral and ethical values ​​in society. In this research we aim to explain strategies for increasing digital literacy from an Islamic education perspective as a form of preventing digital harassment. Using qualitative methods and a literature study approach. We dive into various sources to provide various data, such as books, scientific journals, and online articles. The data analysis technique uses thematic analysis and content analysis. The end of this research shows that there are several strategies to increase digital literacy as a form of preventing digital harassment in accordance with Islamic education. First, instilling Islamic moral and ethical values ​​in every human being. Second, developing knowledge and skills about information and communication technology. Third, developing the character of people with good character and high morals. This strategy must be implemented effectively in the Islamic education process in schools as well as in the general public in order to create a generation that is responsible and has noble character in the digital era.
THE INDONESIAN JOURNALISTS ASSOCIATION (PWI) IN RIAU DURING THE NEW ORDER ERA 1968-1998
Authors: Dhanti Salsabila Azis  , Bunari  , Ahmal
Published: August 2024

The Minister of Information Regulation in Indonesia in 1969 stipulated that Indonesian journalists are required to become members of an Indonesian journalists’ organization approved by the government. Until June 1998, only one organization, the Indonesian Journalist Association (PWI), was recognized. In Riau, PWI was first chaired by H. Moeslim Roesli, serving from 1966-1968. Previously, in August 1963, a temporary representation of PWI Riau was formed with the following structure: Aspan Diar – Chairperson, A. Moeis Hadjads – Vice Chairperson, Noerbahrij Joesoef – Secretary, G.N.T Ilyas – Vice Secretary, Harun Al Rasyid – Treasure, accompanied by two Commissioners, A. Rachman Junus XI. The method used in this research is the Historical method. The historical method seeks to study past events, describing and analyzing these facts in depth. PWI Riau has several roles for journalists aimed at achieving common goals. And PWI Riau faces several challenges that they can resolve professionally through their activities.
Pagelaran Seni dalam Tradisi Malam Bujang Gadis di Kabupaten Lahat Pasca-penghapusan Sistem Marga (1983-2008)
Authors: Jumaidi Susanto , Hamdan Tri Atmaja
Published: August 2024

Seni pertunjukan dalam tradisi Malam Bujang Gadis merupakan budaya masyarakat marga di Kabupaten Lahat yang sarat akan nilai, fungsi, dan tujuan. Akan tetapi, sistem marga tersebut dihapuskan melalui Keputusan Gubernur Sumatera Selatan tanggal 24 Maret 1983 Nomor 142 KPTS/1/1/1983. Penelitian ini bertujuan untuk mendeskripsikan proses penyelenggaraan seni pertunjukan pada masa sistem marga, dinamika sosial politik pasca penghapusan sistem marga, dan pengaruhnya terhadap eksistensi seni pertunjukan. Dengan menggunakan metode sejarah yang meliputi heuristik, kritik sumber, interpretasi sumber, dan historiografi, penelitian ini bersumber dari Laporan Rapat Adat Marga, data Badan Pusat Statistik Kabupaten Lahat, bahan visual, dan sejarah lisan. Hasil penelitian menunjukkan bahwa pada masa sistem marga, seni pertunjukan mencerminkan nilai, norma, dan etika sosial, meliputi seni tari dan seni sastra daerah, hiburan tradisional, dan forum pelestarian kesenian daerah. Akan tetapi, pasca penghapusan sistem marga, perubahan sosial politik berdampak pada kehidupan sehari-hari, sehingga terjadi pergeseran dalam penyelenggaraan seni pertunjukan. Perubahan tersebut kemudian diadaptasi oleh para bujang dan gadis dengan mempengaruhi unsur-unsur pertunjukan seni seperti norma, etika, fungsi, bentuk seni, serta model dan praktik pertunjukan seni dalam tradisi Malam Bujang Gadis di Kabupaten Lahat.
Terapi Islami Ala Padepokan Iqro’ Terhadap Fenomena Pergaulan Bebas di Desa Kolam Kecamatan Percut Sei Tuan
Authors: Septiana Tiara , Nasution Muhammad Ali Azmi
Published: August 2024

In Kolam Village, the rise of negative behavior among the community and teenagers, especially promiscuity, demands special treatment to protect the younger generation from deviant actions. One approach to dealing with this problem is through religion. This research explores the application of Islamic therapy at Padepokan Iqro' as a solution to overcome the phenomenon of promiscuity. This therapy involves religious practices such as dhikr, prayer, and reading the Koran. Researchers feel it is important to highlight how Padepokan Iqro' applies Islamic therapy in dealing with promiscuity. The method used in this research is qualitative, with data collection techniques through interviews, observation, documentation and literature study. The research results show that the Islamic therapy implemented at Padepokan Iqro' in the form of religious activities such as dhikr, prayer and reading the Koran, aims to help the community, especially teenagers, in reducing social problems such as promiscuity.
Collaborative Governance in Accelerating Stunting Reduction through Corporate Social Responsibility
Authors: Hanny Rizky Wasiat Safira , Valiant Salomo Roy
Published: August 2024

This research aims to explore collaborative governance in accelerating the reduction of stunting through Corporate Social Responsibility (CSR) programs in Warakas Village, North Jakarta. The Ketapang Kuning program, a CSR initiative, successfully reduced the stunting rate from 19.3% to 12% in 2022. This study employs a qualitative approach with data collection techniques that include field studies and literature reviews. The results indicate that collaboration between the private sector, government, and community is crucial in addressing stunting issues. Key factors supporting the success of this program include power-resource-knowledge asymmetries such as knowledge, managerial capabilities, and financial resources from the business sector, as well as incentives to participate in the form of internal and external motivations like rewards, and collective facilitative leadership and transparency. The discussion of this research emphasizes the importance of corporate social responsibility (CSR) in reducing stunting and how effective collaboration between various parties can produce significant impacts. The collaboration between the government and the private sector, as demonstrated by PT. PLN IP Priok PGU, serves as a concrete example of how human resources and available funds can be optimally utilized to achieve common goals in stunting reduction.
Andrik Sulistiyawan Sukarno and the Managerial State of Indonesia
Authors: Sulistiyawan Andrik
Published: August 2024

The book, Authoritarian Modernization in Indonesia’s Early Independence Period: The Foundation of the New Order State, 1950-1965, is a remake of the author’s PhD dissertation in Leiden University in the Netherlands, and, it consists of seven chapters and three major discussion parts i.e., 1) elite ideology and formation, 2) the development of institutions and the importation of ideas and ideologies during the 1950s, 3) the development of both national planning and scientific management within the context of the Guided Democracy.
THE RELATIONSHIP BETWEEN WORKLOAD, TECHNOSTRESS, WORK LIFE BALANCE AND EMPLOYEE PERFORMANCE IN THE REGIONAL SECRETARIAT OF THE CITY OF SURABAYA
Authors: Reny Elvira Septyandini  , Dewie Tri Wijayati Wardoyo  , Andre Dwijanto Witjaksono
Published: August 2024

Bureaucratic Reform is one way to achieve good governance and make fundamental changes and renewals to the government administration system, especially in terms of institutional (organizational), administrative and human resource aspects. Through improvements to human resources. This study was conducted at the Regional Secretariat of Surabaya City with the aim of determining the relationship between the influence of workload, technostress, work life balance and employee performance. The research method is a quantitative approach where variables are measured using a Likert scale. The population in this study were employees who use technology in their work. Sampling was taken with a 95% confidence level using the Slovin technique, 193 people were obtained. The research variables consist of three independent variables, namely workload, technostress, work life balance and the dependent variable is employee performance. Data collection was carried out by distributing questionnaires. The results of the data collection were then analyzed using the Structural Equation Modeling Technique using the SMART PLS – 3 application. The results of the study showed that: (1) Workload has a positive effect on Technostress at the Surabaya City Regional Secretariat (2) Technostress does not affect Employee Performance at the Surabaya City Regional Secretariat. (3) Workload does not affect Employee Work Life Balance at the Surabaya City Regional Secretariat. (4) Work Life Balance has a positive effect on Employee Performance at the Surabaya City Regional Secretariat (5) Technostress has a negative effect on Work Life Balance at the Surabaya City Regional Secretariat (6) Workload does not have a significant negative effect on Employee Performance at the Surabaya City Regional Secretariat.
ANALYSIS OF THE INFLUENCE OF HUMAN RESOURCE COMPETENCE AND SERVICE QUALITY ON CUSTOMER SATISFACTION OF THE REGIONAL SECRETARIAT OF SURABAYA CITY
Authors: Warih Anggraini  , Dewie Tri Wijayanti  , Andre Dwijanto Witjaksono
Published: August 2024

The purpose of this study is to determine the influence of human resource competence and service quality on customer satisfaction of the Surabaya City Regional Secretariat. This research is a quantitative descriptive research. Data collection was carried out through the distribution of questionnaires with a research sample of 122 respondents from a population of 176 respondents. The statistical analysis used in this study is Multiple linear regression with the help of Software SPSS. Data testing instruments are carried out by data validity tests, data reliability tests and The classical assumption test consists of a normality test, a multicollinearity test, an autocorrelation test, and a heterokedasticity test. The method used to test the hypothesis is to use the Partial Influence Test (t- Test), the Simultaneous Influence Test (Test F) and the Determination Test (R2). The results of the study show that there is an influence of human resource competence, tangibles, reliability, responsiveness, assurance, and Empathy have a positive and significant effect both partially and simultaneously on customer satisfaction of the Derah Secretariat of the City of Surabaya.
BULUREJO-BANYUWANGI VILLAGE FUND POSTULATE AS SUPPORTING THE EFFECTIVENESS OF EMPOWERING PRE-PROSPEROUS COMMUNITIES
Authors: Iqbal Ramadan  , Hary Priyanto  , Herwin Kurniadi
Published: August 2024

The existence of Village Funds is useful for improving public services, alleviating poverty, advancing the village economy, overcoming development gaps, and strengthening village communities as subjects of development. This research aims to determine, describe and analyze the use of Village Funds for empowerment programs for underprivileged communities in Bulurejo Village. Based on the analysis of research findings, the empowerment program supported by the Village Fund directly and indirectly provides stimulus to improve the economy. Recommendations for the use of Village Funds for empowerment programs for underprivileged communities focus on aspects of empowerment problems, identification of community responses, selection of empowerment policy options, and implementation of the use of Village Funds.
Indonesia-Japan Cooperation During Covid-19
Authors: Setiawan Filzah Nazurah , Siagian Sagita Natasya
Published: August 2024

The outbreak of the Covid-19 pandemic, caused by the SARS-CoV-2 virus from the coronavirus family responsible for SARS and MERS, originated in Wuhan and quickly spread globally. International collaboration has been pivotal in the fight to achieve endemic control. Every nation has strived to acquire Covid-19 vaccines to safeguard their populations. For example, Indonesia forged a bilateral partnership with Japan to secure Covid-19 vaccines. Japan holds a strategic position as one of Indonesia's top five investors. Throughout the pandemic, the Indonesian Ministry of Foreign Affairs maintained close communication with its Japanese counterpart to request support in obtaining the Covid-19 vaccine. This collaboration was made possible by Indonesia's independent and proactive foreign policy, which created extensive opportunities for cooperation during the pandemic. This study aims to present the outcomes of the Indonesia-Japan collaboration in procuring Covid-19 vaccines for Indonesia, showcasing the implementation of an independent and proactive foreign policy that can yield substantial benefits.
MANEJO DA ESQUIZOFRENIA RESISTENTE AO TRATAMENTO: REVISÃO SISTEMÁTICA DE ESTRATÉGIAS FARMACOLÓGICAS E PSICOSSOCIAIS
Authors: Azevedo Barbosa Yasmin , Achilles da Silva Neto José , Monteiro de Souza Gustavo , De Castro Machado Fabiana , Rebello Misukami Davi , Costa Mendes Sabrina , Carolina Calaça de Lima Isadora , Roberto Naves Miranda Guilherme , Cangussu Freitas Vinícius , Araújo Moreira de Melo Viviane , Villela Amaral Marreiro Laura , Vinícius Cordeiro Costa Marcus , Guerino Doretto de Souza Mariana , Nóbrega Lima Nathália
Published: August 2024

A esquizofrenia é um transtorno psiquiátrico severo, frequentemente tratado com antipsicóticos, mas alguns pacientes não respondem adequadamente a essas medicações, resultando em esquizofrenia resistente ao tratamento. Este estudo revisa o manejo dessa condição, com foco na definição de resistência e nas abordagens terapêuticas disponíveis. A resistência ao tratamento é identificada com base em critérios específicos, incluindo falha em dois tratamentos antipsicóticos adequados e persistência dos sintomas. A clozapina é considerada a principal opção para pacientes com esquizofrenia resistente, sendo necessário um monitoramento rigoroso devido aos possíveis efeitos colaterais graves. Para iniciar o tratamento com clozapina, é essencial que o paciente tenha contagens hematológicas adequadas e esteja disposto a seguir o protocolo de monitoramento. Além da clozapina, outras abordagens podem incluir terapias psicossociais e, em alguns casos, eletroconvulsoterapia (ECT) ou outros medicamentos. A escolha do tratamento deve ser adaptada às necessidades individuais do paciente e ao perfil de resposta ao tratamento. Em resumo, o manejo da esquizofrenia resistente ao tratamento requer uma combinação de estratégias farmacológicas e psicossociais, com o objetivo de melhorar a eficácia do tratamento e a qualidade de vida dos pacientes.
Indicações Cirúrgicas para Reparação de Hérnia Inguinal em Pacientes Idosos: Uma Revisão Compreensiva
Authors: Cardoso Vitor , Dos Santos Lima Pablo , Talarico de Morais Nicolly Beatriz , Joviniano Chagas Luann , Silva Costa Júlia , Cortes Drubi Luciano , De Oliveira Perobelli Matheus , Quintão Zacarias Siqueira Quintão Zacarias Siqueira , Do Couto Tonholo Lucas , Holanda Gurjão Thayane , Checon Moreira Luiza , Moreira de Carvalho Lilian
Published: August 2024

Objetivo: O objetivo deste estudo é revisar e discutir as indicações cirúrgicas para reparo de hérnia inguinal em pacientes idosos, focando na segurança, viabilidade e resultados das diferentes abordagens cirúrgicas. Métodos: Uma revisão narrativa foi conduzida utilizando a base de dados PubMed para coletar estudos relevantes publicados até setembro de 2023. Os termos de busca incluíram "reparo de hérnia inguinal," "pacientes idosos," "cirurgia laparoscópica," "cirurgia aberta," "segurança," "viabilidade," e "resultados." Os critérios de inclusão foram estudos publicados em inglês que abordassem especificamente o reparo de hérnia inguinal em pacientes com 65 anos ou mais, comparando as abordagens cirúrgicas laparoscópica e aberta. Resultados: Os achados sugerem que tanto o reparo laparoscópico quanto o aberto são opções viáveis para pacientes idosos, com a cirurgia laparoscópica mostrando vantagens na redução da dor pós-operatória, estadias hospitalares mais curtas e menores taxas de infecção. No entanto, a cirurgia aberta permanece uma escolha popular devido à sua simplicidade e ampla familiaridade entre os cirurgiões. As complicações e os resultados variaram ligeiramente entre as técnicas, enfatizando a importância da avaliação individual do paciente e da experiência do cirurgião. Conclusão: O reparo de hérnia inguinal em pacientes idosos pode ser realizado de forma segura e eficaz utilizando abordagens laparoscópicas ou abertas. A escolha da técnica deve ser adaptada à saúde geral do paciente, comorbidades e experiência do cirurgião. São necessários mais ensaios clínicos randomizados em larga escala para solidificar as diretrizes e otimizar os resultados para essa crescente população de pacientes.
Estudo epidemiológico de esquistossomose no Nordeste do brasil no período de 2019 a 2023
Authors: Santos Matheus da Silva , Pereira Letícia Maria Fernandes , Menezes Matheus Jales , Souza Matheus Paiva de , Lopes Maryanna Fernanda N. Monteiro , Martins Thais Soares Matos de Melo , Costa Averlândio Wallysson Soares da
Published: August 2024

Este artigo tem como objetivo realizar uma análise epidemiológica a respeito do quadro de esquistossomose na região do Nordeste brasileiro. Esse trabalho é do tipo quantitativo e descritivo, o qual utilizou dados presentes no sistema de informação de agravos de notificação relacionados aos casos de esquistossomose nas nove unidades federativas quem compõem a região do Nordeste do Brasil, ademais o período de análise do estudo foi de 2019 a 2023. Com base nas informações colhidas, foi constato que 3606 casos da doença no Nordeste, com maior prevalência de casos na população de sexo feminino, com 2002 casos do total, ademais a faixa etária de 40 a 59 anos foi a que se destacou pelo maior número casos, seguida da população de 20 a 39 anos como as mais afetas pela doença no período do estudo. Em relação aos estados do Nordeste, a Bahia foi o território que mais se sobressaiu com 1408 casos de esquistossomose. É possível concluir que a esquistossomose é um problema de saúde pública no Nordeste brasileiro, sendo necessárias ações públicas para o enfrentamento dela, através de medidas em educação básica e medidas de controle do hospedeiro intermediário da patologia.
Estratégias Multidisciplinares para o Manejo do Transtorno do Espectro do Autismo (TEA) em Crianças
Authors: Primo Borges Lauhanda , Diniz da Costa Freire Kelly Daiana , Rodrigues Maia Santos Celina , Henrique Costa Paulo , Dutra Fonteles Luciano , Dos Santos Paz Larissa , Lins Alves Maria Clara , Madeira Ferraz Débora , Azevedo Matos Fernanda , Do Vale Mecenas Dauana , Roosevelt Souza Tenorio Franklin , Barbosa Martins Iana
Published: August 2024

Introdução: O Transtorno do Espectro Autista é um distúrbio caracterizado pela alteração das funções do neurodesenvolvimento, que podem englobar alterações qualitativas e quantitativas da comunicação, para que seja possível uma abordagem qualificada é necessário estratégias individuais e a coparticipação dos familiares. Objetivos: Analisar e descrever estratégias utilizadas pelos profissionais multidisciplinares quanto ao manejo do transtorno do espectro autista. Métodos: Trata-se de uma revisão da literatura, a qual utilizou os bancos de dados SciELO e Google Acadêmico como apoio. Resultados e discussão: Diante das manifestações comportamentais presentes em crianças com TEA, é necessário a presença de pessoas qualificadas desde o primeiro contato para diagnóstico precoce, quanto para suporte contínuo e integrado. Conclusão: Terapias vêm promovendo melhorias significativas em aspectos comportamentais e funcionais e a inclusão da família no processo terapêutico é fundamental para o progresso da criança.
EVOLUÇÃO DO PERFIL EPIDEMIOLÓGICO E CLÍNICO DA DOENÇA DE CHAGAS AGUDA NO BRASIL: ESTUDO DE UMA DÉCADA
Authors: Lima Andressa Bianca Reis , Carvalho Clara Vitoria Cavalcante , Vieira Vithória Emanuelle Souto , Cavalcante Erika da Silva , Souza Ana Letícia de Souza e , Souza Erik Rogai de , Borges Alex de Souza , Vasconcelos Estefane Cavalcante , Costa Fernanda Prates , Bett Fernanda , Verri José Takamori , Queiroz Lílian Ruth Ferreira , Carlos Pâmella de Oliveira , Tomas Brenda Carrion , Carvalho Ruth Gorete dos Santos , Paschoa Andre , Caltran Leticia Baldin , Guilhon Luana Amorim
Published: August 2024

A doença de Chagas é causada pelo protozoário Trypanosoma cruzi, que infecta espécies de triatomíneos.A fase aguda da doença de Chagas é associada a muitos sintomas que podem variar de leves a graves, tornando o diagnóstico clínico desafiador devido à semelhança com outras doenças infecciosas. Trata-se de um estudo descritivo,retrospectivo e quantitativo com base em dados secundários obtidos no Departamento de  Informática do Sistema Único de Saúde (DATASUS), pelo Sistema de Notificação e Agravos (SINAN) e Sistema de Morbidade Hospitalar (SIH). As variáveis analisadas foram: .ano de notificação, região de residência, faixa etária, cor/raça, sexo, modo provável de infecção,  critério de confirmação e evolução. O total de casos entre 2012 e 2022 foi de  3.212. A Região Norte foi a região com o maior número de casos de doença de Chagas confirmados, correspondendo a 95,29% ( n=3.061). Com relação à faixa etária, nota-se maior frequência  em adultos com idade entre 20 e 39  anos, equivalente  a 34,15% (n=1.097). O sexo masculino foi o mais diagnósticado por doença de Chagas aguda ( 53,76% ). No que tange, cor/etnia, constata-se maior frequência de indivíduos pardos (80,32%). O critério de diagnóstico mais empregado foi o laboratorial correspondendo a 94,73%( n=3.043). A maioria da amostra apresentou provável transmissão oral, sendo equivalente a 81,63 % ( n=2.622). Desse modo,  a realização de investigações adicionais sobre a prevalência da Chagas aguda na população brasileira é crucial para o desenvolvimento de políticas públicas destinadas à prevenção e controle da doença.
ANÁLISE COMPARATIVA DO PERFIL EPIDEMIOLÓGICO DOS CASOS DE DENGUE NO BRASIL DURANTE O PRIMEIRO TRIMESTRE DOS ANOS DE 2023 E 2024: UM ESTUDO ECOLÓGICO
Authors: Florenzano Beatriz Moraes , Cambraia Audrey Tue Domingos Diniz , Mello Karen Paes , Pereira Lourrayne Braga , Pereira Lourena Braga , Silva Anita de Souza
Published: August 2024

A dengue é uma arbovirose causada por um Flavivirus com quatro sorotipos identificados no Brasil – DEN1, DEN2, DEN3 e DEN4 – sendo o primeiro o mais explosivo, causando grandes epidemias em curto prazo e alcançando milhares de pessoas rapidamente. Esta pesquisa tem como foco a análise retrospectiva de dados epidemiológicos sobre a dengue no Brasil durante o primeiro trimestre dos anos de 2023 e 2024. Por se tratar de um país tropical com clima quente e úmido, o Brasil possui um ambiente propício para proliferação do vetor da dengue. Atualmente, tudo indica que o Brasil enfrenta a pior epidemia de dengue da história, visto que diferentes estados e municípios decretaram estado de emergência devido ao aumento no número de casos da doença comparados ao mesmo período do ano anterior. Para a realização deste estudo, foram utilizados dados de notificações de casos de dengue registrados pelos sistemas de vigilância epidemiológica nacional (SINAN), disponibilizados pelo Ministério da Saúde do Brasil e pelo  Departamento  de  Informática  do  Sistema  Único  de  Saúde  (DATASUS). Esses dados incluíam informações sobre o número total de casos de dengue notificados, distribuídos por região geográfica, faixa etária, raça, sexo e classificação final da doença (dengue, dengue com sinais de alarme, dengue grave, entre outros). A metodologia inclui a tabulação e análise detalhada dos casos notificados, permitindo uma compreensão aprofundada sobre a distribuição da doença nas diferentes regiões brasileiras nos anos de 2023 e 2024. Foram calculadas as proporções de casos de dengue em relação ao total de notificações, bem como as proporções de casos graves e óbitos em relação ao total de casos confirmados. O objetivo principal deste trabalho é mapear e comparar a evolução da dengue no Brasil, identificar padrões sazonais e geográficos, e detectar possíveis fatores que influenciaram o aumento dos casos ao longo do período estudado. O estudo reforça a importância da vigilância epidemiológica contínua da dengue e a implementação de medidas integradas de saúde pública para controlar a propagação da doença e proteger a saúde da população brasileira.
Hipnoterapi, Relevansinya Dalam Mempengaruhi Hidup Manusia
Authors: Fitri Isnaini Nurdiana , Verlandes Yuliasnita , Hadi Purnomo Agoes
Published: August 2024

Didalam kehidupan, manusia memiliki berbagai target yang mengakibatkan tekanan dalam hidupnya. Tak terkecuai remaja, dengan segala fenomena nya mereka memiliki tekanan yang tinggi terkait kehidupan sosial, dalam aktivitas pembelajaran atau harapan orang tua yang tidak sesuai ekspektasi nya. Tujuan penelitian ini adalah untuk mengetahui relevansi hipnoterapi didalam membantu menyelesaikan permasalahan yang dihadapi manusia terutama remaja. Dengan tahapan treatmen dan terapis akan diketahui bagaimana hipnoterapi mengintervensi pola pikir dan pola hidup manusia. Selanjutnya berdasarkan hasil pengamatan dari literasi diketahui dampak yang muncul seiring treatmen yang dilakukan hipnosan terhadap klien. Menggunakan metode penelitian studi literasi yang sistematik, penelitian ini memberikan hasil bahwa treatment dilakukan dengan tahapan sebagai berikut ;Preinduction interview, Deepening, Termination (terminasi), Depth level test (tes kedalaman hipnoterapi) dan Post hypnotic behavior (perilaku pasca hipnosis). Tahapan tersebut untuk menjamin adanya optimalisasi dampak terapis yang dilakukan oleh hipnosan terhadap klien. Relevansi hipnoterapi untuk mengurangi stres pada remaja sesuai artikel yang dirujuk tersebut signifikan berdasarkan hasil uji statistik ANOVA dan t-test yang dilakukan pada setiap artikel, dengan nilai p value: 0,000; <.001; <.01; dan <0,02. Teknik hipnoterapi yang dapat digunakan untuk mengurangi stres pada remaja yaitu hipnoterapi dasar, group hypnotheraphy, self hypnotherapy, dan hipnoterapi gabungan seperti hipnoterapi dengan augmented reality technology (AR) dan Mindful hypnotherapy (MH).
 
Kata kunci : Hipnoterapi, solusi, stres, manusia
Preclinical Assessment of a Cannabinoid CB2 Receptor Antagonist in a Murine Model of Cerebral Malaria
Authors: Borrego Escartín Ana , Gómez-Cañas María , García Gómez-Heras Soledad , Marín-García Patricia , Fernández-Ruiz Javier , Diez Amalia
Published: August 2024

Malaria is a most important parasitic disease due to its highest impact worldwide. It results in around 200 million clinical cases and 0,5-1 million deaths per year, mainly due to cerebral malaria (CM), a life-threatening neurological syndrome that predominantly affects predominantly children under five years old. CM follows neurological alterations leading to the death if left untreated, and, even when it is treated, it is fatal in 15-20% of cases. Moreover, among the survivors, more than 10% of the children develop neurological sequelae. Consequently, there is an urgent need to find therapies to attenuate these neurological signs. Recent evidence has proposed the endocannabinoid system, which plays an important neuromodulatory function in the central nervous system (CNS), also including immunomodulation preferentially exerted by CB2 receptor. Previous studies have shown that the genetic ablation of this receptor improved mice survival against CM, suggesting a potential for the pharmacological treatment of CM with selective antagonists of this receptor. Considering this background, we investigated CM therapy by a classic CB2 antagonist SR144528 in a murine model of the disease. First, we carried out binding studies with SR144528 to confirm its pharmacodynamic profile (binding affinity [Ki] value = 2.34 ± 0.61 nM; and efficacy [IC50] = 96.17 ± 1.41 nM, at the CB2 receptor). Second, P. berghei ANKA infected C57BL/6 mice were treated daily with SR144528 and assessed for parasitemia growth and neurological alterations. 30% of the treated mice showed partial recovery of CM symptoms with 20% increased survival, but finally succumbing to hyperparasitemia and severe anemia. These preliminary preclinical results suggest that, although part of the CM course might be modulated by the pharmacological blockade of the CB2 receptor, other elements trigger the lethal outcome. Thus, while our hypothesis could not be completely validated in this CM model, we detail here all obtained results for further research.
Cognitive Functions, Mood and Sleep Quality after Two Months of Intermittent Fasting
Authors: Batorek Maja , Hromatko Ivana
Published: August 2024

Intermittent fasting is being popularized as a method beneficial not only for weight loss, but also for overall psychological functioning and well-being. However, there is only a handful of studies examining the latter claims. The aim of this open-label study was to contribute to the understanding of the relationship between fasting-based diets, and cognitive functions and other mental health factors such as mood and sleep quality. The research was conducted on a sample of 105 healthy volunteers who were placed in either the experimental (fasting) group (n = 76) or the control (no change in diet regimen) group (n = 29). For a period of 2 months, the experimental group adhered to a time-restricted eating (TRE) form of intermittent fasting: Participants were instructed to fast from eating or drinking for 16 hours per day. Participants in the control group did not adhere to any specific dietary regimen. Cognitive functioning (attention, memory, working memory and executive functions), as well as sleep quality and several mood dimensions (anxiety, depression, fatigue, hostility, friendliness, cheerfulness, concentration, energy) were measured across three time points: Prior to the beginning of the study, and one month and two months later, respectively. Results showed no significant group x time point interactions on any of the measures. In conclusion, the results of this study do not corroborate the notion that TRE regimen significantly influences cognitive functions, mood or sleep of healthy individuals. While fasting-based diets successfully regulate weight, the claims regarding their beneficial effect on psychological functioning in non-clinical populations are yet to be proven.
Chemical Constituents of Loranthaceae (Mistletoes): A Review
Authors: Muhammad Kamal Ja’afar
Published: August 2024

This article review is designed to bring some updates on the phytochemistry of the Loranthaceae family in order to throw more light on future research priorities. Loranthaceae family is the leading pantropical semi parasitic shrubs generally termed mistletoe. They consist of about 75 genera and 1000 species growing in many countries of Africa, Asia, Australia, Europe, South America and New Zealand with diverse widespread uses in adornment, food and medication. The literatures for this review was collected from various online databases: Google Scholar, PubMed, Research gate, Science Direct, Scopus and web of Science for nine genera namely, Globimetula, Scurrula, Dendrophtoe, Loranthus, Phragmanthera, Tapinanthus, Taxillus, Tripodanthus and Viscum based on the type of phytochemicals, popularity and environmental setting. Chemical studies of the Loranthaceae species have produced a number of important phytochemicals belonging to different classes. The recent investigations led to the discovery of several secondary metabolites such as alkaloids, flavonoids, phenolic compounds, lignan and neolignans and triterpenes. Hence this review represents a comprehensive assessment of the phytochemical studies carried out on Loranthaceae plants and could be a source of therapeutically beneficial products.
Optimization of Solar Hybrid Gravity System with Battery Energy Storage for Elevation Systems
Authors: Ismail Mohd Ridhuan , Abdul Majid Zafri Azran , Ihsan Sany Izan , Mohd Azmi Mohd Syahriman , Sopian Kamaruzzaman , Abdul Aziz Moria Hazim
Published: August 2024

This research studies the performance and efficiency of a solar hybrid gravity system integrated with battery energy storage. The study aims to optimize the design using a 50-Watt Solar PV, an 18Ah SLA Battery, and a Water Gravity Energy Storage Tank. Energy consumption was evaluated using the SLA Battery, Solar PV, and a 22-Watt Water Pump at various tank heights to measure efficiency improvements and battery lifespan extension. The methodology involved three procedures with five data loggers: a flow meter, a pyranometer, and three unit Watt Meter. Initially, a fully charged SLA Battery was tested at different tank heights (1.5m to 3.5m) every 15 minutes. Subsequently, the 50-Watt Solar PV was tested directly at a 3-meter height. Lastly, the Solar Hybrid Gravity System with Battery Energy Storage was monitored for seven days at a 3-meter height. Results indicated a 600% increase in battery performance at 80% Depth of Discharge (DOD), suggesting the battery's optimal use as a backup power source, thereby extending its lifespan. The SLA Battery shows a 22.1% charging and discharging loss at 5% DOD, while the 22-Watt Water Pump is achieved an 11.0 L/min rate at peak solar radiation, with a maximum motor power of 24.32 Watts. The minimum solar radiation required for efficient pump operation was 300 W/m². In conclusion, the study optimizes the solar hybrid gravity system's energy efficiency, reduces battery dependence, and enhances battery lifespan, promoting sustainable solutions for elevation applications.
Green Fluorescence Property of Chromone-based Hydrazone Towards Zn2+ Ion
Authors: Hermanto Nur Aziani , Juahir Yusnita , Mustafar Suzaliza , Mohamad Sharif Aisyah , M. Osman Uwaisulqarni , Ulianas Alizar
Published: August 2024

Excessive concentration of Zn in the environment may lead to bad toxicological responses that can affect human health and create numerous challenges in the environment. Therefore, it is very important to develop a sensitive method such as selective chemosensors based on fluorescence property which does not require laborious work in order to detect Zn metal ion. A formylchromone-thiosemicarbazide with two chloro derivatives namely DFCTSC was synthesized from reflux reaction of 6,8-dichloroformylchromone (DCF) and thiosemicarbazide (TSC) in ethanol. The characterisation of ligand structure was determined by using spectroscopic techniques such as Fourier transform infrared spectroscopy (FT-IR), ultraviolet-visible spectroscopy (UV-VIS) and nuclear magnetic resonance spectroscopy (NMR). Meanwhile, the fluorescence property of DFCTSC in the presence of Zn ion was recorded using fluorescence spectrophotometer. The result showed DFCTSC has a good fluorescence behaviour towards Zn ion by giving turn-on green fluorescence at peak 500 nm and emit light when it observed under UV light. The behaviour displayed the ability of ligand to be used as a potential fluorescent chemosensor for detecting Zn2+.
Chemical Diversity of Indole Alkaloids from Malaysian Kopsia Species (Apocynaceae) and Their Biological Activities
Authors: Wan Hanafi Wan Nur Huda , Mohamad Taib Mohamad Nurul Azmi , Jumaryatno Pinus
Published: August 2024

The genus Kopsia, which belongs to the family Apocynaceae, has been used extensively in traditional treatment. This mini-review provides a comprehensive analysis of the chemical diversity of indole alkaloids from Malaysian Kopsia species and their biological activities. Fifteen species with 164 indole alkaloids have already been studied and successfully isolated and characterised. Most of them are categorised as aspidofractinine, aspidospermane and eburnane types. The literature and references for this manuscript were obtained from various sources including SciFinder®, Reaxys®, ScienceDirect®, PubMed Central®, NIH National Library of Medicine, Google Scholar and The Plant List®.
A Review on Chemical Constituents and Pharmacological Action of the Genus Lindera
Authors: Zaini Nur Nabilah , Wan Salleh Wan Mohd Nuzul Hakimi , Salihu Abubakar Siddiq , Abed Salam Ahmed
Published: August 2024

The genus Lindera consists of approximately 100 species that are widely distributed in tropical and subtropical areas throughout the world. It is represented by widely well-known medicinal and aromatic plants that produce various phytochemicals with potential pharmacological actions. This review attempts to summarize the information on the phytochemicals of Lindera species together with their biological properties. The data and information were collected via an electronic search engine which are Scopus, ScienceDirect, Google Scholar, PubMed, and SciFinder. Sesquiterpenes represent the major chemical compounds that have been characterised in Lindera species, as well as alkaloids, flavonoids, and phenolics. These compounds were shown to possess anticancer, antifibrotic, anti-inflammatory, antitumor, antioxidant, anti-arthritic, cytotoxic, antiallergic, and antihyperlipidemic properties. The outcome of these studies will further support the therapeutic potential of the genus Lindera and provide convincing evidence for its future clinical applications in modern medicine.
Detection of SpaP and vicR Genes in Non-biofilm Producing Streptococcus mutans Isolated from Dental Caries and Plaque
Authors: A. Aljubouri Sahira , H. Alobaidi Khalid
Published: August 2024

Evidence accumulated over many decades has clearly shown that Streptococcus mutans is a major agent in dental caries. S. mutans SpaP gene (Cell Surface Antigen) mediates the binding of these cariogenic bacteria to tooth surfaces. The aim of this study was to detect the presence of SpaP and vicR genes in non-biofilm forming Streptococcus mutant isolated from dental plaques. In this study, 120 clinical samples were obtained from different dental clinics and hospitals in Baghdad. 26 Bacterial isolates identified as Streptococcus mutans by using selective media (Mitis-salivarius agar) and microscopic examination after gram staining then confirmed S. mutans by molecular detection using SpaP genes. Interestingly all 26 isolates were non-biofilm forming after microtiter plate assay based on the crystal violet staining method, and negatively resulted for the detection of vicR gene which responsible for biofilm formation. 10 antibiotics (Doxycycline, Ofloxacin, Tetracycline, Erythromycin, Vancomycin, Clindamycin, Rifampicin, Imipenem, Amikacin and Cefepime) were used to examine sensitivity of S. mutans isolates, all isolates were multi-drugs resist (MDR) for all 10 antibiotics used. We can conclude that absence of biofilm forming ability does not affecting antibiotic resistance and virulence of Streptococcus mutance.