bluuebunny/crossref_metadata_2025 huggingface dataset:
Validity of Radiographic Analyses Between Hand-Drawn and Computer-
Aided Measurements: A Double-Blinded Test-Retest Trial
Authors: Fedorchuk Curtis , Comer Robert D. , McRae Christi , Bak David , Lightstone Douglas F.
Published: February 2023

Background:

Spinal radiographic analyses are valid and reliable practices used for patient
management in healthcare. Technologies and tools used for these analyses need to be valid and reliable.

Objective:

This study investigates repeated accuracy for validity and intra- and inter-examiner reliability
of computer-aided lateral spinal radiograph measurements using PostureRay® EMR software.

Methods:

Rectangle renderings representing lateral spinal radiographic views were created to remove
examiner interpretation of anatomical landmarks as performed on actual radiographs to examine the
objective repeated accuracy of PostureRay® software. A blind, randomized, repeated measure design
was performed using four examiners trained and experienced with the Harrison Posterior Tangent
method of measurement. Each examiner analyzed the spine renderings using a hand-drawn and PostureRay
® method multiple times. A fully crossed design whereby examiners performed multiple assessments
per rendering using each analysis method was used to assess intra- and inter-examiner reliability
within each method and a formal comparison of the two methods.

Results:

Using hand-drawn and PostureRay® methods, examiners displayed very high intra-examiner
reliability with correlation values greater than 0.999 for each combination of trials. PostureRay® method
showed consistent accuracy of measurements. Further, there was no statistical difference in average
concordance between hand-drawn and PostureRay® methods for the lateral cervical, thoracic, and
thoracolumbosacral spinal regions.

Conclusion:

This study reports a very high degree of intra- and inter-examiner reliability of radiographic
line drawing methods and establishes concurrent validity of PostureRay® EMR software in
determining angles and displacements of lateral spinal alignment as an equivalent method to the handdrawn
method.
Interactions of Butyrylcholinesterase with Neuroblastoma-associated
Oncoproteins
Authors: Baranowska-Kortylewicz Janina , Kortylewicz Zbigniew P. , McIntyre Erin M. , Sharp John G. , Coulter Don W.
Published: February 2023

Background:

Emerging data indicate that BCHE, a gene encoding the enzyme butyrylcholinesterase,
is a negative prognostic marker in MYCN-amplified neuroblastoma. Levels of butyrylcholinesterase
in children newly diagnosed with neuroblastoma are proportional to MYCN amplification and the
response to therapy. To better understand the functions of butyrylcholinesterase in neuroblastoma, we
examine interactions of this enzyme with several neuroblastoma-associated kinases and provide in depth
review of known associations.

Methods:

BCHE-deleted cells (KO) were produced from MYCN-amplified BE(2)-C cells (WT) by the
CRISPR-Cas9 targeted disruption of the BCHE locus. Activation levels of several oncoproteins and the
expression of N-Myc in KO were compared to WT cells. N-Myc protein expression, multiplexed detection
of relative protein expression and phosphorylation of 71 tyrosine kinases and 17 proteins in the
MAPK pathway were assessed using Western immunoblotting and microarrays in exponentially growing
untreated cells and in cells exposed to the genotoxic stress.

Results:

BCHE locus disruption and butyrylcholinesterase deficiency result in the loss of N-Myc protein
and a significant deactivation of several kinases associated with the aggressive neuroblastoma phenotype
as well as major changes in the phosphorylation of upstream and downstream partners of these kinases

Conclusions:

Butyrylcholinesterase appears to contribute to the activation of several pathways in
MYCN-amplified cells including FGF-R1, Ltk, TrkB, and Ros1. Deletion of BCHE and ensuing butyrylcholinesterase
deficit deactivate these pathways suggesting the role of BChE as a novel druggable target
in neuroblastoma therapy.
Unilateral Transverse Leukonychia in a Patient Receiving Isotretinoin Treatment with Concomitant Renal Impairment: A Case Report
Authors: Alsaidan Mohammed Saud
Published: February 2023

Aims:

Leukonychia is a white discoloration of nails. Although it is usually clinically insignificant, it can serve as a clue for systemic diseases that is sometimes life-threatening.

Case Report:

A 24-year-old male patient, with resistant acne vulgaris not responding to topicals nor systemic antibiotics and with a history of renal impairment and untreated recurrent high blood pressure readings, was started on isotretinoin. Three months later, he presented with a unilateral true transverse leukonychia with a worsening renal impairment. The patient was started on antihypertensive medications. The patient was seen two months later with unilateral transverse leukonychia fading (moving distally).

Results:

Repeated laboratory tests showed slightly increased serum creatinine, improved but still high protein/creatinine ratio. The fading of leukonychia while continuing isotretinoin treatment and after starting antihypertensive medication that has a renal protective effect may indicate a renal-associated leukonychia.

Conclusion:

This is probably the first reported unilateral leukonychia without identified local/unilateral causes.
THE EFFECT OF BLUE LIGHT IRRADIATION ON ARTIFICIAL BILIRUBIN SOLUTION
Authors:   Physics Department, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Malang,  Indonesia, 65145, Herwiningsih Sri Herwiningsih , Anggraeni Dewi , Dewi Mustika
Published: February 2023

Hyperbilirubinemia is an accumulation of unconjugated bilirubin in the skins and mucous membrane of newborns. Phototherapy is often used to treat hyperbilirubinemia by using visible light. The aim of this study was to investigate the effect of blue light irradiation on artificial bilirubin solution. The artificial bilirubin solution was prepared using methyl red powder and acetic acid. The blue light emitted from fluorescent light tube model 52 (Philips) were measured its spectrum and intensity, and then used to irradiate the artificial bilirubin solution with concentration of 5, 10, 15,20 and 30 mg/dl. The transmitted intensity of the solution before and after irradiation was measured using spectrophotometer. The result shows that the spectrum of the blue light emitted from the fluorescent tube light met the criteria to be used as phototherapy light source. The minimum required intensity is obtained at distance of 35 – 40 cm from the lamp. The effect of blue light irradiation on artificial bilirubin solution is obviously observed in a low solution concentration, indicated by a higher difference of the transmitted intensity of the solution before and after irradiation. A longer irradiation or a higher intensity is required for a higher concentration in order the phototherapy to be effective.
DISSEMINATION OF COLORING TECHNOLOGY WITH NATURAL DYES ON HANDCRAFTED BATIK
Authors:   Department of Agroindustrial Technology, Universitas Brawijaya, Malang, Indonesia, A. Mustaniroh Siti
Published: February 2023

Handcrafted “Batik Sidomulyo” is an agro industrial development as an attempted agroindustrial support in Sidomulyo Flower Resort Village that adopted ornamental plants, flowers and local wisdom themed batik motifs for supporting tourism potentials. In 2020, SMEs “Batik Sidomulyo” have been facilitated with Mini Wastewater Treatment Plant (WWTP) so it could decrease difficulties in coloring and liquid waste disposal. These MSMEs have limited technology in the natural coloring production process and coloring. Use of natural coloring is beneficial in color innovation and creation of batik’s quality. The objective of this study is for determining the effectiveness of efficacy in the dissemination of natural coloring production technology and coloring process with natural substance on batik. The implementation method through technical counseling and dissemination about natural coloring production technology that utilises local wisdom such as “secang” and “tingi” wood (red color), jackfruit wood and “jelawe” (yellow color) and nila/indigo leaf (blue color). Using natural coloring proved to be effective in increasing the competitiveness of handcrafted market. Implementation of activities involves practitioners from SMEs handcrafted from Trenggalek that organised training as well as mentoring on natural coloring producing process and coloring process until batik finishing process for 5 days. The efficiency level of technology dissemination are the knowledge and skills improvement of handcrafted batik so could produce natural coloring independently as well as to improve the quality of the handcrafted that have the competitiveness as one of the travel souvenirs.
SWITCHING STRATEGY AS AN EFFORT TO SURVIVE DURING THE PANDEMIC (BUSINESS IN THE CITRUS PLANTATION SECTOR)
Authors:   Faculty of Economics and Business, University of Brawijaya, Malang, 65145, East Java, Indonesia, Irianto Gugus
Published: February 2023

The agricultural sector has an important role in national economic development because of the abundant potential of natural resources and can support economic growth in rural areas. According to the Center for Agricultural Data and Information Systems, the Indonesian Ministry of Agriculture in 2020 stated that during the Covid-19 pandemic, the agricultural sector in Indonesia has proven to be a mainstay in stabilizing the country's economy. Until 2020, Bocek Village is the only village in Karangploso District, Malang Regency that does not yet have a Village-Owned Enterprises (VOE). With the Doctoral Service Program (Program Doktor Mengabdi), Bocek Village has established VOE in 2020. The DSP program in Bocek Village aims to create jobs and improve community welfare. The DSP program which is under the auspices of the Institute for Research and Community Service (IRCS) Universitas Brawijaya, is expected to be able to produce Leading Assisted Villages for the development of the agricultural and agro-industrial sectors in Bocek Village. The implementation of the DSP Program in Bocek Village has entered its 2nd year (2021) with a focus on strengthening the role of VOE in developing the community business sector. The team of DSP plans community service activities in the form of strengthening Bocek VOE in agricultural, agro-industry clusters and dissemination of technology and information. An alternative solution for the Bocek VOE business unit is to create a derivative product from citrus fruits, namely orange juice. The raw material for orange juice is the result of the process of sorting ripe oranges that have fallen to the ground. Marketing of citrus fruit juice products is planned by opening a Marketplace that can reach a wider target market. In addition, the potential for online sales can now be said to be more profitable than conventional because it has been supported by the rapidly growing digitalization transformation making online sales and marketing more profitable.
EMPOWERING THE MAGERSAREN COMMUNITY: TECHNOLOGY DISSEMINATION FOR GROUND COFFEE ADDED VALUE IMPROVEMENT
Authors:   Agricultural Technology Faculty, Universitas Brawijaya, Malang, East Java, Indonesia, Atsari Dewi Ika
Published: February 2023

This paper is aimed to share the community service experiences held at Boro Sumbersari hamlet which is located at 98A UB forest plot. Boro Sumbersari hamlet is inhabited by Magersaren community. The Magersaren community are farmers and forest workers who depend on forest for their livelihoods. Magersaren has been practicing agroforestry for a long time. They grow Robusta and Arabica coffee among other forest plants. Currently coffee is a favorite beverage, the number of its consumers continues to increase. Many people are interested in the ground coffee beans made by Magersaren traditionally, but it has not been widely marketed. The purpose of this community service program is to generate an alternative source of Magersaren household income, through the added value improvement of local flavored ground coffee beans they have. The added value of magersaren’s ground coffee beans can be increased through product development technologies such as attractive packaging techniques and the creation of new variants ground coffe beans by adding brown sugar and powdered ginger. The execution of community service activities that have been carried out consists of: 1)program socialization; 2)focus group discussion; 3)production, packaging and management training; 4)small-business starting up; 5)program evaluation. These community service activities are held during the social distancing due to the COVID-19 pandemic. This condition becomes an obstacle to the effectiveness of program implementation. The start-up small business needs to be continuously supported in order to survive through a critical period of business development, especially under economic pressure during the pandemic.
DIVERSIFICATION OF TEA PRODUCTS TO INCREASE MSME’S INCOME IN PELAWANFOREST AREA, CENTRAL BANGKA
Authors:   Industrial Engineering, Universitas Brawijaya, Indonesia, Oktavianty Oke
Published: February 2023

This study aimed to assist the forestry managers of Pelawan Forest in increasing their income through the diversification and preparation of the products produced to meet food safety and other required standards so that the resulting products are ready to be exported to foreign countries. Aspects of Good Manufacturing Practice (GMP) – HACCP as a food safety aspect were used as an approach for product diversification. Lean manufacturing and green sustainability methods were used as methods to safe guard Pelawan Forest as a protected forest with Pelawan Forest being provided with assistance so that they are able to carry out the production process while still paying attention to the diversity of animals that live in it. In the future, Pelawan Forest will be prepared as a Pelawan Botanical Garden, which can serve as a tourism forest that can become a mainstay in Central Bangka Regency, Bangka Belitung Province, with products that are ready to be marketed in Indonesia and overseas.
RESPONSE OF FISH FARMERS TO AQUACULTURE DEVELOPMENT PROGRAM IN SEGODOREJO, SUMOBITO, JOMBANG
Authors:   Dept of Fishery Product Technology, Faculty of Fisheries and Marine Science, Brawijaya University, Jl.  Veteran 65145, Malang Indonesia, A. Prihanto Asep
Published: February 2023

Segodorejo Village located in Sumobito Subdistric, Jombang Regency, East Java Province. This village is affected by the COVID 19 Pandemic. The economy is experiencing a process of sluggishness as a result of the pandemic. The “doctor serves” program is done to overcome the problems of youth efforts in fishery cultivation. The research aims to analyze the effectiveness and success of the activities of the serving doctor who has been carried out. The research design using survey methods with questionnaire instruments. The data obtained were analyzed descriptively in the form of characteristics of fish farmers to the program. The results showed some aspects of fish farmers observed to be obtained, namely: most are classified as productive age, education is relatively low and moderate with the average education in vocational/high school, the main job is private, on average has run a business with a length of business time between 5–14 months, and most cultivators have two ponds. Furthermore, the cultivator’s response to the program was influenced by age, education, occupation, length of effort, time and respondent’s number of pools. This study concludes that the activities of the “Doctor of Service” program are responded to well and associated with increased business and economy.
Upaya Pengembangan Desa Wisata Punten Pasca Dibentuknya Kelompok Sadar Wisata Di Desa Punten Kota Batu
Authors:   Universitas Brawijaya, Malang, Indonesia, Junining Esti
Published: February 2023

Pandemic Covid-19 rupanya bisa dijadikan masa pengembangan dan persiapan potensi desa wisata, baik dari segi SDM hingga pengolahan produk. Penggerak wisata atau kelompok desa wisata dapat memanfaatkan masa pandemic untuk melakukan pendekatan studi strategi. Metode praktikum dipilih dalam melakukan pendekatan ketika melakukan pelatihan. Pengabdian ini membahas bagaimana masyarakat Desa Wisata Punten mampu memberikan pelayanan prima, mampu membukukan keuangan dengan apik, meningkatkan layanan produk hasil pertanian, serta menghasilkan branding untuk produk baru yang dihasilkan oleh POKDARWIS Punten.
Peningkatan Kesejahteraan Masyarakat Melalui Kegiatan Pendampingan Budidaya Maggot di Desa Tambak Kalisogo, Kecamatan Jabon, Kabupaten Sidoarjo
Authors:   Fakultas Perikanan dan Ilmu Kelautan, Universitas Brawijaya, Maftuch Maftuch
Published: February 2023

Desa Tambak Kalisogo merupakan salah satu desa dampingan PT. PGN,Tbk melalui program Corporate Social Responsibility (CSR). Hingga saat ini TPA di desa itu memiliki kapasitas sampah lebih dari 92%. Maggot merupakan salah satu serangga yang dapat digunakan pada teknik biokonversi dan tidak berpotensi menyebarkan penyakit. Metode yang digunakan yakni persiapan kegiatan, pelaksanaan kegiatan, sosialisasi, pelatihan pemilahan sampah dan penanganan sampah organik untuk media budidaya maggot, pelatihan dan praktik budidaya maggot, pelatihan kewirausahaan, serta monitoring dan evaluasi kegiatan. Hasil evaluasi menunjukan bahwa masyarakat Desa Tambak Kalisogo melalui BUMDes ingin serius melaksanakan kegiatan budidaya maggot dengan fasilitasi pembangunannya dari pendanaan CSR PT. PGN, Tbk. Kegiatan dari persiapan, pelatihan, hingga fasilitasi pembangunan paket budidaya maggot saat ini sudah terimplementasikan dan sudah menghasilkan maggot mulai dari stadia telur, stadia larva, hingga stadia lalat.
Budidaya Benih Lobster Pasir (Panulirus Homarus) Dengan Resirculation Aquaculture System (Ras) Di Pokdakan “Pesona Bahari”, Grand Watudodol, Banyuwangi
Authors:   Fakultas Perikanan dan Ilmu Kelautan, Universitas Brawijaya, Mukhammad Amrillah Attabik , Fadjar Mohamad , Andayani Sri , Retno Andriani Dwi , Eko Putra Sri Sentanu I Gede , M. Amrillah Attabik , Aisyah Diana Aisyah
Published: February 2023

Puerulus or lobster seed (Panulirus homarus) often found in Banyuwangi teritory, in line with government regulations that prohibit to export lobster seeds, Lobster seed trading with seed size segmentation can be an alternative to improve the economy of people who are running the Covid19 pandemic. Seed size segmentation is needed because lobster cultivation as a consumption measure takes a long time. One of the efforts made in its cultivation in order to obtain growth rate and survival rate is Recirculation Aquaculture System (RAS). The aim of this activity is to produce “cricket” size seeds raised by RAS. Cultivation activities was carried out 2 months with different types of feed. Parameters measured every two weeks are growth and survival rate. Water quality measured every day were temperature, DO, pH and salinity, while ammonia, nitrite, and nitrate were measured every two weeks. The results obtained was 100% survival rate.
Development Of Processed Food Production Units For The Dasawisma Mawar Group, Kebobang Village, Wonosari District, Malang Regency
Authors:   Departemen Teknik Biosistem, Fakultas Teknologi Pertanian, Universitas Brawijaya, Yulianingsih Rini , Susilo Bambang , Lastriyanto nang
Published: February 2023

The Dasawisma Mawar group is one of the Dasawisma groups in KebobangVillage, Wonosari District, Malang Regency that has 40 active members engaged in the food business. The business development of this group needs to be improved to build a strong company that can compete in the global market. The aims of the community service activities were to increase the mastery of technology by entrepreneurs, send the knowledge to apply the production processes that meet standards and improve the production process in one industry, namely the vacuum-fried chips industry. The service activities were carried out include: The practice of vacuum frying; Course on vacuum frying machines, good manufacturing processes, and packaging to provide insight for future developments; Improvement in production processes by applying suitable spinner, adding plastic sealers to speed up the packaging process, and procuring work clothes. Other outputs produced are the design of a chip production unit according to the GMP standard and the production layout design to improve production capacity.
Pelatihan Uji Fitokimia Senyawa Metabolit Sekunder Tanaman Secang (Caesalpinia sappan L.) Kepada Perkumpulan Pendidik Sains Kimia Indonesia (PPSKI)
Authors:   Jurusan Kimia, Fakultas MIPA, Universitas Brawijaya, Mariyah Ulfa Siti , Dhiaul Iftitah Elvina , Rahman M. Farid
Published: February 2023

The content of active compounds in plants can be analyzed by phytochemical tests. One of the herbal plants that is widely consumed is secang (Caesalpinia sappan). Secang is usually stored in the form of herbal tea and brewed with hot water then drunk to reduce throat inflammation or any other symtompts. To introduce simple research activities in schools, training on phytochemical tests of secondary metabolites of local plants (in this case secang) was conducted for chemistry teachers who are members of the Indonesian Chemical Science Educators Association(PPSKI). The method is carried out by providing online training using zoom meeting, video tutorial, discussion, question and answer, and assignment. In this training, pre-test and post-test were carried out to measure the participants abilities before andafter the training. The average value of the pretest was 50 points (scale of 100) and increased to 70 points (scale of 100). There was an increase in participants knowledge by 20% after the training. This phytochemical test training provides chemistry teachers with new insights to conduct simple research with simple materials which is available in schools and their surrounding.
Utilization Waste Of Bone And Intermuscular Bone Milk Fish (Chanos Chanos) As A Zero Waste Business In Msme Anugrah Mitra Lestari, Malang
Authors:   Fishery Processing technology, FFMS UB, Jl Veteran Malang, Kartikaningsih Hartati , Asmara Wati Lina ,   Fishery Agrobisnis FFMS UB, Jl Veteran Malang, Yahya Yahya ,   Fishery Processing technology, FFMS UB, Jl Veteran Malang, Supriyadi Supriyadi ,   PSDKU Fishery Socio-economic FFMS UB, Jl Veteran Malang, Ayu Christianty Putri Rhytia , Kurniaty Rika
Published: February 2023

MSME Anugrah Mina Lestari utilizes milk fish bone and intermuscular bone from milk fish grill cake processing as fish cracker and fish shredded as an effort to zero waste. The problem of these products was oily enough and the dryness of fish cracker was not uniform. The Serving Doctoral Programmed provided the solution of the problem by provided help with the spinner machine and oven drying. With the equipment assistance, the partner of this programmed, MSME Anugrah Mina Lestari can increase the product until 66.6% (fish crackers) and 60% (fish shredded) and increased organoleptic acceptance from moderate like (score 5) to like (score 6). It should be testing the product for proximate, mineral content and product durability listed in the packaging although there was already the prototype packaging. It also necessaryto arrange food home product license to market expand.
European Periodical Research 2020–30: Voices and Visions from the ESPRit 2021 Roundtable
Authors: Stead Evanghelia
Published: February 2023

This paper, a reflection of the roundtable from the ninth ESPRit annual conference in Bochum, brings together five researchers from different disciplines: history, linguistics, translation studies, media studies, and English. It signals their experience in periodical research, raises several methodological and cross-disciplinary questions, and briefly looks into future developments nurtured by current practice and open questions. It represents a lively moment in exchange as international research on periodicals swiftly evolves.
Engagement With the Centers for Disease Control and Prevention Coronavirus Self-Checker and Guidance Provided to Users in the United States From March 23, 2020, to April 19, 2021: Thematic and Trend Analysis
Authors: Shah Ami B , Oyegun Eghosa , Hampton William Brett , Neri Antonio , Maddox Nicole , Raso Danielle , Sandhu Paramjit , Patel Anita , Koonin Lisa M , Lee Leslie , Roper Lauren , Whitfield Geoffrey , Siegel David A , Koumans Emily H
Published: February 2023

Background

In 2020, at the onset of the COVID-19 pandemic, the United States experienced surges in healthcare needs, which challenged capacity throughout the healthcare system. Stay-at-home orders in many jurisdictions, cancellation of elective procedures, and closures of outpatient medical offices disrupted patient access to care. To inform symptomatic persons about when to seek care and potentially help alleviate the burden on the healthcare system, Centers for Disease Control and Prevention (CDC) and partners developed the CDC Coronavirus Self-Checker (“Self-Checker”). This interactive tool assists individuals seeking information about COVID-19 to determine the appropriate level of care by asking demographic, clinical, and nonclinical questions during an online “conversation.”

Objective

This paper describes user characteristics, trends in use, and recommendations delivered by the Self-Checker between March 23, 2020, and April 19, 2021, for pursuing appropriate levels of medical care depending on the severity of user symptoms.

Methods

User characteristics and trends in completed conversations that resulted in a care message were analyzed. Care messages delivered by the Self-Checker were manually classified into three overarching conversation themes: (1) seek care immediately; (2) take no action, or stay home and self-monitor; and (3) conversation redirected. Trends in 7-day averages of conversations and COVID-19 cases were examined with development and marketing milestones that potentially impacted Self-Checker user engagement.

Results

Among 16,718,667 completed conversations, the Self-Checker delivered recommendations for 69.27% (n=11,580,738) of all conversations to “take no action, or stay home and self-monitor”; 28.8% (n=4,822,138) of conversations to “seek care immediately”; and 1.89% (n=315,791) of conversations were redirected to other resources without providing any care advice. Among 6.8 million conversations initiated for self-reported sick individuals without life-threatening symptoms, 59.21% resulted in a recommendation to “take no action, or stay home and self-monitor.” Nearly all individuals (99.8%) who were not sick were also advised to “take no action, or stay home and self-monitor.”

Conclusions

The majority of Self-Checker conversations resulted in advice to take no action, or stay home and self-monitor. This guidance may have reduced patient volume on the medical system; however, future studies evaluating patients’ satisfaction, intention to follow the care advice received, course of action, and care modality pursued could clarify the impact of the Self-Checker and similar tools during future public health emergencies.
Factors Associated With Open Access Publishing Costs in Oncology Journals: Cross-sectional Observational Study
Authors: Koong Alex , Gardner Ulysses Grant , Burton Jason , Stewart Caleb , Thompson Petria , Fuller Clifton David , Ludmir Ethan Bernard , Rooney Michael Kevin
Published: February 2023

Background

Open access (OA) publishing represents an exciting opportunity to facilitate the dissemination of scientific information to global audiences. However, OA publishing is often associated with significant article processing charges (APCs) for authors, which may thus serve as a barrier to publication.

Objective

In this observational cohort study, we aimed to characterize the landscape of OA publishing in oncology and, further, identify characteristics of oncology journals that are predictive of APCs.

Methods

We identified oncology journals using the SCImago Journal & Country Rank database. All journals with an OA publication option and APC data openly available were included. We searched journal websites and tabulated journal characteristics, including APC amount (in US dollars), OA model (hybrid vs full), 2-year impact factor (IF), H-index, number of citable documents, modality/treatment specific (if applicable), and continent of origin. All APCs were converted to US-dollar equivalents for final analyses. Selecting variables with significant associations in the univariable analysis, we generated a multiple regression model to identify journal characteristics independently associated with OA APC amount. An audit of a random 10% sample of the data was independently performed by 2 authors to ensure data accuracy, precision, and reproducibility.

Results

Of 367 oncology journals screened, 251 met the final inclusion criteria. The median APC was US $2957 (IQR 1958-3450). The majority of journals (n=156, 62%) adopted the hybrid OA publication model and were based in Europe (n=119, 47%) or North America (n=87, 35%). The median (IQR) APC for all journals was US $2957 (1958-3540). Twenty-five (10%) journals had APCs greater than US $4000. There were 10 (4%) journals that offered OA publication with no publication charge. Univariable testing showed that journals with a greater number of citable documents (P<.001), higher 2-year IF (P<.001), higher H-index (P<.001), and those using the hybrid OA model (P<.001), or originating in Europe or North America (P<.001) tended to have higher APCs. In our multivariable model, the number of citable documents (β=US $367, SD US $133; P=.006), 2-year IF (US $1144, SD US $177; P<.001), hybrid OA publishing model (US $991, SD US $189; P<.001), and North American origin (US $838, SD US $186; P<.001) persisted as significant predictors of processing charges.

Conclusions

OA publication costs are greater in oncology journals that publish more citable articles, use the hybrid OA model, have a higher IF, and are based in North America or Europe. These findings may inform targeted action to help the oncology community fully appreciate the benefits of open science.
Efficacy of the Cigarette-Burning application combined with medication intervention for smoking cessation in China: A Randomized Clinical Trial (Preprint)
Authors: Wei Xiao-Wen , Qin Rui , Liu Yong-Zhuang , Liu Zhao , Cheng An-Qi , Zhou Xin-Mei , Su Zheng , Cui Zi-Yang , Li Jin-Xuan , Zhao Liang , Xiao Dan , Wang Chen
Published: February 2023

BACKGROUND

Although smartphone application (app) for smoking cessation was considered as a promising strategy, the results of studies about apps were inconsistent, and there were few studies on combinations of usual interventions and apps in smoking cessation.

OBJECTIVE

To evaluate the efficacy of the Cigarette-Burning application combined with medication intervention for smoking cessation.

METHODS

A parallel, open-label randomized clinical trial was conducted with a ratio of 1:1 allocation into the bupropion plus app group and bupropion group. All participants received bupropion intervention. Besides, participants in the bupropion plus app group were required to download and use the Cigarette-Burning app, which developed based on smoking cessation guidelines. Follow-up visits were conducted at weeks 1, 2, 4, 9, 12, and 24 after initiation of treatment.

RESULTS

400 participants were included in the intention-to-treat analysis from July 2019 to June 2021. The median (IQR) age was 48.0 (38.0-59.0) years, and 374(93.5%) were men. The continuous abstinence rate at 9-12 weeks was significantly higher in the bupropion plus app group (39.5%) than in the bupropion group (27.5%) (OR=1.64, 95%CI 1.04-2.60, P < 0.05). The similar result was found for 24-week sustained abstinence rate. The results of subgroup analysis expressed that the 9-12w continuous abstinence rate was significantly higher in the bupropion plus app group when smokers were at older age, higher education level, higher degree of tobacco dependence or younger age at starting smoking (P < 0.05).

CONCLUSIONS

This trial provides evidence that the Cigarette-Burning smartphone application significantly increased smoking abstinence when combined with medications and could be an accessible complement to smoking cessation support.

CLINICALTRIAL

Chinese Clinical Trial Registry (No.: ChiCTR1800016919; http://www.chictr.org.cn).
Letter from Editor Prof. N. Grygorieva
Authors: Grygorieva N.V.
Published: February 2023

No abstract
Letter from Deputy Editor-in-Chief Prof. H. Resch
Authors: Resch H.
Published: February 2023

No abstract
Sustainable Development, Electricity Generation and Renewable Energy substitution in Middle East Countries and Cooperation of Iran
Authors: Shahrtash Fatemeh, M.
Published: February 2023

The energy category over the world has been considered as Coal, Natural Gas, Hydro, Nuclear, Wind, Oil and Solar PV by means of 38%; 29%, 16%; 10%and %5 respectively. Where the main reserve holders of Russia, Iran, Qatar, U.S.A. and Saudi Arabia r, have regarded natural gas as an alternative of energy. In which Iran is in the second position after Russia. Where the electricity generation has been considered by China, U.S.A, India, Russia, Japan and Canada respectively and Iran is in the 14th place. Besides renewable energy, capacity installed over the world is in terms of GW-2019 has been defined by China, U.S.A, and Brazil, India, and Germany respectively. However, solar power installed in Middle East Countries and Africa (MENA) is in terms of Terra watt-hour per year by Algeria, Libya, Saudi Arabia, Egypt, Morocco and Tunisia. Whereas solar power markets has been classified by China, India, Japan, Australia, Mexico, Turkey and Netherland in GW-2018 respectively Iran has been considered for the energy resource of Oil as 25%, Natural Gas as 69%, and Hydroelectricity as 6% in 2018 as the main respectively. China, U.S.A., India, Japan and Australia have respected the solar power market consideration in GW-2018 as the most important countries. Other considerations for CO2 emission over the globe has been made by China (27.2%), U.S.A (14.58%), India (6.82%), Russia (4.68%), Japan (3.33%) and, Germany (2.21%) as the most important ones.
The effect of freeze-thaw on the performance of recycled concrete pavement
Authors: Haile Shoddo Elias , Liu Yuanzhen
Published: February 2023

Freeze-thaw damage is one of the most serious issues that can affect pavement made of recycled concrete in cold places. The recycled concrete pavement freeze-thaw deterioration mechanism still needs to be fully understood. In this study, a number of different experimental investigations were conducted. on several concrete specimens that contained differing percentages of RCA replacements by volume (0%, 30%, 50%, 70%, and 100%, respectively). Several freeze-thaw cycles have been exposed to the concrete specimens. In order to assess the performance of the casted specimens, the mass loss, relative dynamic modulus of elasticity (RDME), and length change were estimated. The results demonstrate that the incorporation of recycled coarse aggregate significantly affects the performance of the specimens. Flexural strength tests have been used to evaluate the degree to which the specimens' mechanical properties have deteriorated. After being subjected to several freeze-thaw cycles. For all mixtures, the 28-day flexural strength values were calculated. The test result shows the flexural strength value of the specimens was inversely proportional to the replacement of RA. The flexural strengths of the specimens dropped as the number of RA increased. Furthermore, the specimens with more RA replacement have a greater drop in flexural strengths. Moreover, an analysis of the freeze-thaw cycle's process and its damage mechanism was revealed.
Cloning of phytase gene from Aspergillus niger 563 and its expression in E.coli system
Authors: Geetha S. , Kumar K. K. , Arul L. , Kokiladevi E. , Balasubramanian P. , Sudhakar D.
Published: February 2023

A phyA was cloned from Aspergillus niger by reverse transcription polymerase chain reaction. The amplified 1404 bp fragment was cloned in a T/A cloning vector and confirmed by sequencing. The isolated phytase gene showed 99.0 % sequence identity at nucleotide and protein level with Aspergillus niger CBS 513.88 phytase. The amino acid sequence from the phyA cDNA contained the consensus motifs, RHGXRXP and HD which are conserved among histidine acid phosphatases. The phytase cDNA was subcloned in pET28a(+) expression vector and expressed in E. coli. The expression of the gene was confirmed through SDS-PAGE analysis. A 52 kDa protein as per the calculated molecular mass of the translational product of phytase gene was observed in crude lysate of E. coli culture induced with IPTG. The protein was purified using nickel based His-bind resin column and checked on SDS-PAGE. The purified recombinant enzyme showed a single band of 52 kDa protein. The phytase activity of pET-phyA IPTG induced E. coli culture and purified phytase was 383.5 U/ml and 826.33 U/ml, respectively.
CuidArte: consolidación de la revista en la difusión del conocimiento
Authors: Beltrán Lugo Norma Ivette
Published: February 2023

Estimada Dra. Guillén, es para mí un gusto hacer esta carta cuya intención radica en reconocer la importancia que ha tenido la revista dentro de la difusión de nuevos conocimientos que aportan en [...]
ESTADO ACTUAL DE ESPECIALIDADES DE ENFERMERÍA EN ARGENTINA: REALIDAD Y DESAFÍO
Authors: Perez Silvia Gabriela , Galarza Salinas Viviana de los Ángeles , Salinas Ermelinda , Damián Saravia Silvio
Published: February 2023

Introducción. La enfermería argentina está transitando un cambio profundo en la formación de grado y posgrado, es probable que los licenciados en enfermería no conozcan cómo continuar con su formación disciplinar. Objetivo.  Conocer la oferta académica de posgrados de especialidad en enfermería acreditadas por la Comisión Nacional de Evaluación y Acreditación Universitaria (CONEAU) a diciembre 2020 en la República Argentina. Metodología. Estudio documental, descriptivo, analítico, con abordaje mixto, se basa en el análisis de información estadística proveniente del catálogo 2020 de posgrados acreditados por CONEAU. La muestra está integrada por las especialidades disciplinares establecidas en dicho documento. Resultados. Se constata que del total de posgrados acreditados en la Argentina (n=3664) se distribuyen de la siguiente manera: doctorado 14%, maestrías 33% y especializaciones 53%, la mayor concentración de ofertas académicas acreditadas se encuentra en la región metropolitana, y por otro lado no hay propuestas de posgrado disciplinar en al menos dos regiones, las especialidades multidisciplinares ocupan un 90% de la oferta académica. Conclusión. Se pone de manifiesto la realidad de ofertas de especialidades acreditadas por CONEAU, sin embargo, sólo el 0.8% (n=15) corresponde a enfermería en comparación de la extensa oferta de otras disciplinas, realidad que conlleva a nuevos interrogantes que deben ser resueltas desde las políticas públicas educativas quienes tienen un rol primordial.
Serie de casos sobre el cuidado al adulto con enfermedad cerebrovascular en el hogar
Authors: Pratz Andrade Ma. Teresa
Published: February 2023

Introducción: La enfermedad cerebrovascular es una de las primeras causas de mortalidad y discapacidad en el mundo, las personas con esta afección presentan diversas limitaciones físicas que le impiden ejecutar actividades de la vida diaria. Por ello, el objetivo de este proyecto fue implementar un programa de cuidado al adulto con enfermedad cerebrovascular en el hogar, el cual buscó conseguir el máximo nivel posible de funcionalidad, reduciendo la incapacidad y aumentando la independencia, en colaboración con la familia. Presentación de los casos: Pacientes que habían presentado un evento cerebrovascular en los seis meses previos al ingreso al programa de cuidado, se desarrolló en la ciudad de Guanajuato, donde los participantes permitieron el acceso a sus hogares, para brindar cuidados personales, rehabilitación, terapia ocupacional y prevención de úlceras por presión, lo anterior apegado al código de ética que rige al profesional de salud. El programa tuvo una duración de 10 semanas, donde participaron ocho personas y sus familias, logrando que 4 participantes disminuyeran su déficit neurológico, 2 mejoraron su puntuación en la escala NIHSS; la funcionalidad de las personas mejoró y no hubo presencia de úlceras. Conclusión: La rehabilitación es prioritaria para la recuperación de las personas por lo que debe comenzar desde el período de hospitalización, así mismo la intervención en el hogar permitió que los cuidados fueran personalizados a las necesidades de cada persona y familia, permitiendo coadyuvar con la recuperación, rehabilitación y re-incorporación del enfermo a su cotidianidad.
A Study on the Housing Support of Agricultural Foreign Workers in the Community Using the FGD Research Method: Focusing on the construction of dormitories for Agricultural foreign workers in Yang Village, Cheorwon-gun
Authors:   Residential Environment Institute Of Korea, Kim Seung hee , Im Hye soon
Published: February 2023

This study examines the current status of housing for agricultural foreign workers and the direction of access to residential support for agricultural foreign workers in the local community. The case study in Yangji Village, Cheorwon-gun, and the Focus Group Discussion (FGD) research method were used.
The results of the study are as follows. Farm owners have limitations in responding to the recently strengthened standards for residential facilities in agricultural foreign workers. Therefore, there is a limit to responding to the standards of residential facilities for agricultural foreign workers, which have been strengthened in terms of policy at the community level, and the search for alternatives at the community level has led to an urgent situation. Accordingly, it was suggested that accommodation jointly operated in the region is necessary to cope with the housing problem of agricultural foreign workers. In addition, it was confirmed that consensus was being formed in local communities such as farm owners, agricultural foreign workers, and related institutions.
This study emphasized the need for a community-level approach to improving residential facilities, which are passed on to farmers employing agricultural foreign workers and increase the burden. Ultimately, it is significant that the discussion on the housing problem of agricultural foreign workers, which has been overlooked, has been expanded to the community level, confirming the possibility of expanding the relationship between agricultural foreign workers as members of rural society.
A Study on the Effects of Changes in the Housing Purchasing Power Index on the Housing Market in Seoul
Authors:   Residential Environment Institute Of Korea, Park Jung-A
Published: February 2023

This study attempted to derive the effect of changes in the Seoul Housing Purchasing Power Index on apartment prices in Jeonju, one of the representative non-metropolitan base cities, and to understand its meaning. The analysis method used VECM in consideration of the characteristics of the variables measured in time series. The summary and implications of the results of this study are as follows.
First, the change in housing purchasing power in Seoul was found to be one of the main variables affecting apartment prices in Jeonju, a local hub city, and in particular, it was found to have a significant impact on the lag behind. In other words, if housing prices in the Seoul metropolitan area soar and housing investors' ability to invest in the Seoul metropolitan housing market decreases, it is interpreted that they are interested in the apartment market in local hub cities with relatively high price advantages over some time difference. Second, it was found that the change in the population had the greatest effect on apartment prices in Jeonju. Finally, unlike research results on housing prices in Seoul and the metropolitan area, changes in major macroeconomic environments such as total currency, economic growth, and consumer price index did not significantly affect housing prices in Jeonju. This result is judged to be because the level of housing prices is very low compared to the metropolitan area, and the merit as an investment good or an inflation hedge is not high.
A Study on the complex characteristics for the Coexistence of Human & Nature in Contemporary Architecture: focused on the analysis of Sou Fujimoto’s architectural works
Authors:   Residential Environment Institute Of Korea, Lee Sang hwa , Lee Ye rin
Published: February 2023

In the 21st century, the industrial society based on materials and capital has changed into a dynamic digital society based on knowledge and information. The principles of various phenomena are also evolving into a new paradigm that includes variability and non-foreseenness.
Complexity science was formed in the second half of the 20th century as a new trend of looking at the complexity of these various areas as a frame.
Based on the complexity theory presented since the 1980s, this study tries to grasp the trends and characteristics of modern architecture from the perspective of social phenomena and examine the three methods recently applied to the works of architect Fujimoto Sou. First, we will understand the characteristics of new trends in the complexity theory and modern architecture, secondly, we will understand the characteristics of the complexity from Fujimoto's architecture concept and method, and thirdly, we will explore the diversity of approaches in complex architecture by comparing design concepts of modern architect and techniques with Fujimoto’s approach.
Fujimoto emphasized coolness in his architectural ideas and focused on natural motifs as a design concept. Furthermore, while implementing this principle spatially, Fujimoto focused on experience and evolution, which is interaction with humans, and explored primitive future architecture oriented toward new architecture as the main principle of complex system theory. This is a paradox of existing architecture, and the architect tried to express uncertainty, nonlinearity, and non-measurability that did not exist in the existing architectural composition. Therefore, new human-centered architecture will need to continue to seek ways to approach new architecture for humans by enhancing a fundamental understanding of nature, namely primitive future architecture in Fujimoto's terminology, by increasing understanding of complex system theory focusing on natural order.
Research on the Scope Setting for the Storm and Flood Disaster Neighborhood Unit: Urban Planning Approach
Authors:   Residential Environment Institute Of Korea, Kim Hui chul , Park Mi jin
Published: February 2023

This study hopes that in establishing a comprehensive improvement plan for the storm and flood disaster neighborhood unit centered on the village-level living area, and implementing the project, management guidelines that can be operated together with the improvement of the system will be prepared so that the plans, projects and construction materials established by other ministries can be used in a complementary manner so that it can be managed as a more effective and comprehensive storm and flood disaster neighborhood unit.
In addition to more specific preliminary reviews, review criteria considering urban planning factors are utilized, and various disaster map data and disaster vulnerability analysis data are used to derive disaster-prone areas.
It is a study to meet the effectiveness of the management guidelines for the comprehensive maintenance plan of the future storm and flood disaster neighborhood unit by presenting systematic and specific clear standards and utilizing data.