bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Peer Coaching as Health Coaching Support on Parenting Self Efficacy to Infant Care in Early Marriage Mother in The Waipare Public Health Center Working Area
Authors: Nelista Yosefina
Published: September 2020

Introduction: Early marriage is a practice that is still common in several countries in the world. Getting married at early age will have an impact on childcare. Marriage at an early age needs to obtain knowledge about childcare. Interventions provided to mothers who marry at early age to change her behavior is health coaching support. The purpose of the study was to analyze the effect of health coaching support by peer coaching method on parenting self-efficacy to infant care in mothers who married at early age. Methods: This study used a quasi-experimental design with one group pre-test and post-test design. The study population was early marriage mothers who had infant. We used purposive sampling technique with a sample of 15 participants. The instrument used in this study was the Maternal Self-Efficacy Scale. Results: The results showed that of the 15 participants, the mean pre-test and mean post-test were 1.73 and 3.46. Wilcoxon test results showed before and after being given health coaching support by peer with p-value 0,000 < α = 0.05, so Ho was rejected and Ha was accepted. This showed that there was a significant influence due to the provision of health coaching support by peer coaching methods on infant care. Conclussions: There was an increase in parenting self-efficacy on infant care in mothers who married at early age. It is expected that parents who married at early age could change their behavior and have confidence in parenting.
The Storyboard Development of Virtual Reality Simulation (VRS) of Nursing Care in Respiratory System Disorders Course
Authors: Permana Ryan Hara , Suryani Mira , Adiningsih Dian , Paulus Erick
Published: September 2020

Introduction :Practicingclinical nursing skills requires high fidelity learning methods but are often constrained by financial factors. Virtual Reality Simulation (VRS) is a practical learning method that is able to project visually the experience of practicing nursing care in a virtually real situation. VRS is financially affordable and portable, allowing students to learn whenever and wherever. This study focused on developing the storyboard of a VRS as a method of practicing nursing care skills in the case of acute respiratory system infection at Faculty of Nursing, Universitas Padjadjaran. Methods: This study utilized qualitative descriptive design.An expert group consists of a paediatric nurse, a senior paediatric nursing lecturer, an e-learning expert and two VR experts was working serially to develop the case and storyboard. The case development stage was conducted using a Focus Group Discussion (FGD) and the storyboard development stage used two workshop sessions. The NLN/Jeffries Simulation was used as a framework to develop the storyboard. Results: The learning objectives, scenes, actions, challenges and redirect elements were identified. The learning objectives is the most essential foundation in building a storyboard. Conclusion: The storyboard template allows subject matter experts to develop VRS that capable to train nursing care skills in a safe and immersive environment.
Weight Addition on Pregnant Women as A Quality Predictor of Family Daily Food Consumption Pattern
Authors: Azza Awatiful , Susilo Cipto
Published: September 2020

Introduction: Pregnancy is a physiological condition experienced by women after marriage. Physical changes and development occur in pregnant women can determine the health conditions of the mother and fetus. Nutritional status of the mother is one of an important key factors in pregnancy. The objective of this study determines the relationship between daily nutritional consumption of family and weight addition on pregnant. Methods: The design used in this study is correlational with cross sectional approach and the data obtained through questionnaires and documentary studies. Data analysis was carried out either quantitatively using Spearman rank or qualitative to deepen the findings in the field. Results: The results of this study found that the P-value 0.002 which means there is a relationship between the nutritional consumption with the nutritional status of pregnant women. The correlation coefficient was 0.309 which means a moderate relationship with positive correlation value implied that the better daily nutritional consumption of family, the higher nutritional status of pregnant women. Conclusions: Understanding the nutritional needs of pregnant women requires good cooperation between family and health workers.
Success Stories From Patient’s with Stroke Recurrence Prevention: A Qualitative Study
Authors: Pangastuti Heny Suseani , Rustina Yeni , Kamso Sudijanto , Sitorus Ratna
Published: September 2020

Introduction: Recurrence is an issue encountered by patients with stroke in Indonesia. Stroke recurrence might occur due to the patient’s inability to perform secondary prevention, particularly the non-pharmacological one, by changing their lifestyle. Many patients with stroke are known to survive longer with no recurrence. This research aimed to explore the experience of the patient with stroke and success in stroke recurrence prevention. Methods: This was a qualitative study using a descriptive exploratory method. Eight post-stroke patients who met the inclusion criteria participated in this research. The data were collected using an in-depth interview. The data were then analyzed using Giorgi method. Results: From the data analysis, it was found these stroke patients could survive without experiencing any recurrence in a certain period of time thanks to some reasons which could be classified in four themes, namely: 1) having a good food management habit, 2) having a good physical exercise/activity habit, 3) using traditional medicine instead of conventional medicine, and 4) there are some factors influencing successful management of stroke recurrence prevention. Conclusions: Patients with stroke, have a good experience and good habits to prevent their stroke recurrence, but they still have a misperception about convention medicine. This result shows the importance of the ability to manage recurrence risk factors in post-stroke patients, to prevent them from having a recurrence. Need further research on the use of traditional medicine in a stroke patient.
The Correlation Between Humidity, Temperature, and Noise With Sleep Quality at Intensive Care Unit (ICU)
Authors: Suparti Sri , Suroso Jebul
Published: September 2020

Introduction: Temperature, humidity, and noise are factors that affect sleep quality. The objective of the research is to determine the effect of humidity, temperature, and room noise on sleep quality of (Intensive Care Unit) ICU patients. Methods: A quantitative research with the cross-sectional approach, involving 84 patients taken by consecutive sampling, with the inclusion criteria of at least having already spent more than two days in ICU, having age between 20-70 years, and being conscious and cooperative. The patients were observed using observation sheets and The Richards-Campbell Sleep Questionnaire (RCSQ). A thermohygrometer and sound level meter for noise recording were used to measure the temperature and humidity. Simple linear regression was used to analyze the data. Results: It was found out that the average sleep quality of patients in the intensive room was 28.51, which categorized as poor sleep quality; the mean humidity in ICU was 56.98; the room temperature was 26.40, and the noise was 66.01. The noise level at the ICU significantly affected the patients’ sleep quality (p-value = 0.020 <0.05), while temperature and humidity did not influence the patients' sleep quality. Conclusion: Most of the respondents had a poor quality of sleep. Controlling the conversation and activities among staff, using earplugs, and modifying the alarm can be done to reduce the noise at the ICU to enhance the quality of sleep of the patients.
Cognitive Therapy and Logotherapy on Depression of Patients With Type 2 Diabetes Mellitus
Authors: Sutinah Sutinah
Published: September 2020

Introduction: Diabetes mellitus (DM) is a severe health disorder that causes physical problems and psychosocial effects. Depression and anxiety are the most common psychosocial problems experienced by people with DM. The purpose of this study was to determine the impact of cognitive therapy and logotherapy on and anxiety in patients with Type 2 diabetes. Methods: A quasi-experimental design has been conducted for the study at a hospital in Jambi Province. The total sample of 90 respondents with a consecutive sampling method. The independent variables are cognitive therapy and logotherapy, while the dependent variables are depression and anxiety. Data were analyzed by paired sample t-test and ANOVA. Results: The results showed that cognitive therapy and logotherapy could reduce depression more than giving cognitive therapy alone with a p-value of 0.0005. Conclusions: Cognitive therapy and logotherapy can be standard therapy in dealing with patients with psychosocial problems.
Touch and Massage on Labor Pain Intensity During First Stage of Active Phase
Authors: Nursanti Irna , Anggraini Dewi , Purwaninigsih Ari
Published: September 2020

Introduction: Labor pain is a challenging issue for nurses designing intervention protocols. Touch and massage therapy is one of non-pharmacology approaches that they could do during labor process. The study was conducted to assess the effectiveness in reducing pain intensity scale on the labor during first stage of active phase. Methods: A quasi-experimental approach was conducted and a purposive sampling technique was used to recruit 56 women who expected to have normal childbirth at a public hospital in Jakarta, Indonesia. They randomly assigned to either received touch and massage intervention (experiment) or not (control). The labor pain intensity was using Verbal Description Scale (VDS) with descriptive statistics, paired, and independent t-test. Results: The result showed that touch and massage therapy had a significant impact on the experimental group (tcalI 2.839, p<0.05). A significant difference also showed among the experimental dan control group during pre-test (tcalI 1.817, p>0.05) and post-test (tcalI 10.77, p<0.05). The study found that a combination of touch and massage therapy was effective to reduce labor pain during active stage. Conclusions: Touch and massage therapy can reduce labor pain intensity, and at the same time serve as closeness and encouragement during the first stage of active phase. It is a cost-effective nursing intervention and can positively influence the quality of women’s birth experiences.
The assessment of landslides disaster mitigation in Java Island, Indonesia: a review
Authors: Zamroni Akhmad , Kurniati Ayu Candra , Prasetya Haris Nur Eka
Published: September 2020

The frequency of landslides and the fact that a large number of people live in the landslides-prone areas lead to a high death toll in Java Island, Indonesia – over 1,112 people in the period between 1999 and 2005. Indonesian National Disaster Management Agency (Badan Nasional Penanggulangan Bencana [BNPB]) reported 2,766 landslides that occurred in Java from 2014 to 2019, with 662 deaths. From its state, it looks as if Indonesia 's disaster mitigation is still weak. It is very essential to a deep understanding of landslides disaster mitigation weakness in Indonesia with the approach of governments, researchers, and local communities action. This research is a review of landslides disaster mitigation in Java Island with the approach of governments, researchers, and local communities action. Furthermore, the purpose of this study is to highlight the driving forces of landslides disaster mitigation in Java Island, Indonesia.

From the assessment of each stakeholder (government, researchers, and local communities), the driving forces of landslides disaster mitigation in Java Island are the central government has commanding disaster management activities to local governments. However, the implementation of landslides disaster mitigation at the regional level has some obstacles such as the lack of residential development planning.Many landslide research results have only become scientific papers but the landslides-prone areas have not been fully paid attention by the local government such as the absence of landslide danger warning signs.In addition, the level of preparedness and awareness among local communities is not constant at any given time. Usually, community preparedness levels can be high following a disaster. It is likely, however, to diminish over time.
Analysis of Shoreline Shift using Satellite Imagery near Makassar City
Authors: Amukti Rian , Adji Arif Seno , Ruslan Syamsuri
Published: September 2020

Shoreline shift have occurred in the Coastal region of Makassar City in recent years due to abrasion and accretion. Spatial temporal feature extraction of the Makassar City Region has been carried out using remote sensing techniques  withRadiometri,  Geometric Corrections and Composite Imagein the Landsat image dataset in 2009 and 2019. This study aims to analyze shoreline shift near Makassar City with remote sensing technology using Landsat imagery data, based on multi-temporal data with visual and digital analysis techniques between 2009 and 2019. This research contributes to local and central government as baseline data (data base) in making decisions for handling coastal areas. The results showed that the length of the Makassar City coastline without including the coastline length of the islands separated from land in a row that is equal to 37.79 km in 2009. While in 2019 there was a significant change that is 49.82 km. This shows the addition of a coastline of 12.03 km in the span of 10 years. These changes are mainly caused by anthropogenic factors, namely the construction of the pier / port and the reclamation and hydro-oceanographic factors, namely waves, currents and tides.
The Permeability of Granite Weathering Soil in Tanjungpinang, Bintan Island, Indonesia
Authors: Erawan Fery , Sukiyah Emi , Hutabarat Johanes , Sudradjat Adjat
Published: September 2020

Bintan Island is a part of Riau Islands Province. On this island, the capital city is Tanjungpinang. The compliance of public facilities such as landfill waste is a priority in this city. Landfill design that suitable in this area is a sanitary landfill system. The soil layer uses to cover the waste in this landfill system. The closure did gradually avoid the disruption of waste processing. The type of soil for its landfill cover has to be able to control the leachate. It controlled by the permeability of the soil.

The methods used in this study are the analysis of the physical and mechanical properties of soil. Rock and soil samples are obtained systematically through trenching. Sampling-based on changes in physical properties of soil that reflect its mechanical properties. A probabilistic approach used to solve the problems and to get accurate results.

The geomorphology of the study area divided into four units. They are very flat terrain, flat terrain, slightly steep hills, and steep hills. The sample used for the study is undisturbed soil. Analysis of the physical and mechanical properties of soil shows the types of soil, such as SW, GM, MH-OH, and CH. However, MH is the most dominant type of soil. Each of the soil types represents a certain degree of weathering. The degree of weathering in the study area varies from the III degree to VI degrees. Rocks are weathering form clay mineral, which compiles the soil. Clay mineral in the soil layer is varied from quartz, illite, kaolinite, gibbsite, goethite, and hematite—the impact of the swelling of clay. The swelling of clay in the study area ranged from low to high. The properties and composition of the soil are affected by the permeability value.
Pengembangan Website Dinas Kesehatan Kota Singkawang
Authors: Irwansyah Muhammad Azhar , Tursina Tursina , Perwitasari Anggi
Published: September 2020

Pembuatan Website Profil Dinas Kesehatan di Kota Singkawang adalah salah satu inovasi dalam penyampaian informasi seputar pelayanan kesehatan di Kota Singkawang. Website ini drancang dengan memanfaatkan bahasa pemograman PHP dan HTML serta diintegrasikan dengan basis data MySQL. Penggunaan library CSS seperti Bootstrap juga digunakan untuk membantu merancang tampilan website agar lebih terlihat dinamis dan user friendly. Dengan adanya Website Profil Dinas Kesehatan Kota Singkawang sebagai media publikasi online ini, maka penyampaian informasi seputar pelayanan kesehatan pada Kota Singkawang dapat berjalan efektif dan efisien yang mana untuk selanjutnya hal ini diharapkan dapat lebih meningkatkan derajat kesehatan masyarakat di Kota Singkawang. Website Profil telah diuji dan menunjukan hasil yang baik. Website dapat berjalan dengan lancar, baik dari sisi interface pengunjung maupun admin. Fungsi fungsi yang dibuat tidak menunjukan adanya anomali maupun suatu error yang fatal dari sistem. Sedangkan untuk error saat penginputan data, website telah dilengkapi dengan error-handling dengan tujuan untuk membantu user dalam menggunakan website dengan mudah dan nyaman.
Implementasi Algoritma Fuzzy C-Means Clustering Sistem Crowdfunding pada Sektor Industri Kreatif Berbasis Web
Authors: Gunawan Wawan , Diwiryo Bagus Seno Prasetyo
Published: September 2020

Perkembangan teknologi setiap tahun semakin maju sehingga memiliki dampak terhadap kemudahan terhadap sektor industri kreatif. Dengan berkembangnya teknologi ini, memberi kemudahan untuk menggalang dana pada sektor industri kreatif berupa sebuah sistem crowdfunding. Pengimplementasian crowdfunding pada sektor industri kreatif dapat dijadikan sebagai alternatif penggalangan sumber pendanaan untuk anak anak negeri. Maka dari itu, dibangun aplikasi berbasis web untuk memudahkan pengguna dalam melakukan penggalangan dana ataupun memberikan dana. Pada penelitian ini, peneliti dapat menggunakan data yang terkumpul pada aplikasi crowdfunding ini menjadi suatu informasi yang dapat dimanfaatkan. Salah satu informasi yang dapat diperoleh adalah kampanye project yang mendapatkan pendanaan terbanyak, terkecil dan belum didanai. Untuk mengetahui hal tersebut, maka dirancang suatu sistem aplikasi crowdfunding berbasis web dengan mengimplementasikan metode fuzzy c-means clustering sebagai metode untuk mengelola datadata yang telah terkumpul. Pengujian sistem pada hasil akhir sistem menggunakan metode fuzzy c-means clustering dengan menggunakan 13 contoh kasus uji, menunjukkan bahwa hasil perhitungan metode ini didapatkan output berupa 3 kriteria yaitu terbanyak 23,1% kampanye project, terkecil 38,5% kampanye project, dan belum didanai 38,5% kampanye project. Berdasarkan hasil analisa ini, algoritma fuzzy c-means clustering bekerja dengan sangat baik untuk mengetahui kampanye project mana saja yang dapat dikembangkan.
Implementasi Sistem Tanya Jawab Berbasis Skenario untuk Mendukung Proses Akademik dengan IBM Watson Assistant
Authors: Toba Hapnes , Wijaya Bryan
Published: September 2020

Dalam makalah ini disampaikan sebuah hasil penelitian dengan memanfaatkan teknologi dari IBM, yaitu Watson Assistant. Watson Assistant digunakan untuk membuat chatbot terkait proses akademik. Analisis dan pengumpulan data dilakukan dengan berbasiskan skenario. Data-data tersebut dibuat ke dalam sebuah graph search. Watson Assistant akan menentukan node dengan nilai kepercayaan tertinggi untuk diberikan sebagai jawaban. Skenario percakapan yang ditanamkan dalam chatbot ini telah diimplementasikan ke dalam bentuk laman web, Facebook Messenger, dan Slack untuk membantu interaksi antara pihak fakultas dengan mahasiswa. Chatbot berperan pula sebagai sistem pendamping forum tanya jawab di dalam course learning system (CLS) untuk pertanyaan-pertanyaan rutin. Berdasarkan hasil uji coba, chatbot berbasis skenario telah dapat menjawab kebutuhan dasar mahasiswa untuk bertanya seputar hal akademis, sebagaimana tercantum dalam buku panduan, khususnya untuk proses perwalian dan deskripsi mata kuliah.
Prediksi Kelulusan TOEFL Menggunakan Metode Resilient Backpropagation
Authors: Okprana Harly , Lubis Muhammad Ridwan , Hadinata Jaya Tata
Published: September 2020

Prediksi kelulusan TOEFL peserta didik Michigan Computer English Course diperlukan untuk meninjau sejauh mana tingkat pemahaman peserta didik. Backpropagation merupakan salah satu teknik yang baik digunakan untuk prediksi, akan tetapi jika backpropagation dalam training data dengan jumlah besar serta parameter-parameter yang digunakan kurang tepat, akan terjadi proses traning data lebih lambat. Maka diperlukan metode optimasi untuk mempercepat training Bacpropagation dalam memprediksi kelulusan dengan menggunakan metode Resilient Backpropagation. Data yang diolah sebanyak 182 data peserta didik tahun 2016-2018. Tingkat akurasi pengujian semakin baik yakni 100% dengan nilai MSE semakin kecil 0.00342 serta nilai Epoch juga semakin kecil menjadi 5. Sehingga penelitian ini menjadi indikator dalam pengembangan prediksi TOEFL dimasa yang akan datang.
An Efficient and Accurate Model for Water with an Improved Non-Bonded Potential
Authors: Mohebifar Mohamad , Rowley Christopher
Published: September 2020

A molecular mechanical model for liquid water is developed that uses a physically-motivated potential to represent Pauli repulsion and dispersion instead of the standard Lennard-Jones potential. The model has three-atomic sites and a virtual site located on the ∠HOH bisector (i.e., a TIP4P-type model). Pauli-repulsive interactions are represented using a Buckingham-type exponential decay potential. Dispersion interactions are represented by both and terms. This higher order dispersion term has been neglected by most force fields. The ForceBalance code was used to define parameters that optimally reproduce the experimental physical properties of liquid water. The resulting model is in good agreement with the experimental density, dielectric constant, enthalpy of vaporization, isothermal compressibility, thermal expansion coefficient, diffusion coefficient, and radial distribution function. A GPU-accelerated implementation of this improved non-bonded potential can be employed in OpenMM without modification by using the CustomNonBondedForce feature. Efficient and automated parameterization of these non-bonded potentials provides a rational strategy to define a new molecular mechanical force field that treats repulsion and dispersion interactions more rigorously without major modifications to existing simulation codes or a substantially larger computational cost.
The Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis
Authors: Sharma Mahima , Abayakoon Palika , Jin Yi , Epa Ruwan , Lingford James P. , Shimada Tomohiro , Nakano Masahiro , Mui Janice , Ishihama Akira , Goddard-Borger Ethan D. , Davies Gideon J. , Williams Spencer
Published: September 2020

The sulfosugar sulfoquinovose (SQ) is produced by essentially all photosynthetic organisms on earth and is metabolized bacteria through the process of sulfoglycolysis. The sulfoglycolytic Embden-Meyerhof-Parnas pathway metabolises SQ to produce dihydroxyacetone phosphate and sulfolactaldehyde and is analogous to the classical Embden-Meyerhof-Parnas glycolysis pathway for the metabolism of glucose-6-phosphate, though the former only provides one C3 fragment to central metabolism, with excretion of the other C3 fragment as dihydroxypropanesulfonate. Here, we report a comprehensive structural and biochemical analysis of the three core steps of sulfoglycolysis catalyzed by SQ isomerase, sulfofructose (SF) kinase and sulfofructose-1-phosphate aldolase. Our data shows that despite the superficial similarity of this pathway to glycolysis, the sulfoglycolytic enzymes are specific for SQ metabolites and are not catalytically active on related metabolites from glycolytic pathways. This observation is rationalized by 3D structures of each of these enzymes, which reveal the presence of conserved sulfonate-binding pockets. We show that SQ isomerase acts preferentially on the b-anomer of SQ and reversibly produces both SF and sulforhamnose (SR), a previously unknown sugar that acts as a transcriptional regulator for the transcriptional repressor CsqR that regulates SQ-utilisation. We also demonstrate that SF kinase is a key regulatory enzyme for the pathway that experiences complex allosteric modulation by the metabolites AMP, ADP, ATP, F6P, FBP, PEP, and citrate. This body of work provides fresh insights into the mechanism, specificity and regulation of sulfoglycolysis and has important implications for understanding how this biochemistry interfaces with central metabolism in prokaryotes to process this major repository of biogeochemical sulfur.
BonDNet: A Graph Neural Network for the Prediction of Bond Dissociation Energies for Charged Molecules
Authors: Wen Mingjian , Blau Samuel , Spotte-Smith Evan , Dwaraknath Shyam , Persson Kristin
Published: September 2020

A broad collection of technologies, including e.g. drug metabolism, biofuel combustion, photochemical decontamination of water, and interfacial passivation in energy production/storage systems rely on chemical processes that involve bond-breaking molecular reactions. In this context, a fundamental thermodynamic property of interest is the bond dissociation energy (BDE) which measures the strength of a chemical bond. Fast and accurate prediction of BDEs for arbitrary molecules would lay the groundwork for data-driven projections of complex reaction cascades and hence a deeper understanding of these critical chemical processes and, ultimately, how to reverse design them. In this paper, we propose a chemically inspired graph neural network machine learning model, BonDNet, for the rapid and accurate prediction of BDEs. BonDNet maps the difference between the molecular representations of the reactants and products to the reaction BDE. Because of the use of this difference representation and the introduction of global features, including molecular charge, it is the first machine learning model capable of predicting both homolytic and heterolytic BDEs for molecules of any charge. To test the model, we have constructed a dataset of both homolytic and heterolytic BDEs for neutral and charged (1 and +1) molecules. BonDNet achieves a mean absolute error (MAE) of 0.022 eV for unseen test data, significantly below chemical accuracy (0.043 eV). Besides the ability to handle complex bond dissociation reactions that no previous model could con- sider, BonDNet distinguishes itself even in only predicting homolytic BDEs for neutral molecules; it achieves an MAE of 0.020 eV on the PubChem BDE dataset, a 20% improvement over the previous best performing model. We gain additional insight into the model’s predictions by analyzing the patterns in the features representing the molecules and the bond dissociation reactions, which are qualitatively consistent with chemical rules and intuition. BonDNet is just one application of our general approach to representing and learning chemical reactivity, and it could be easily extended to the prediction of other reaction properties in the future.
Metal Free Amino-Oxidation of Electron Rich Alkenes Mediated by an Oxoammonium Salt
Authors: Millimaci Alexandra , Meador Rowan , Dampf Sara , Chisholm John D.
Published: September 2020

4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium tetrafluoroborate (Bobbitt’s salt) effectively activates electron rich alkenes and promotes the addition of anilines. This transformation provides a direct, transition metal free method for amino-oxidation of alkenes under mild conditions. The relative stereochemistry of the amino-oxidation is influenced by solvent effects, with both the syn and anti amino-oxidation products being accessible from identical starting materials.
In Situ Monitoring of Mechanochemical Covalent Organic Framework Formation Reveals Templating Effect of Liquid Additive
Authors: Emmerling Sebastian , Germann Luzia S. , Julien Patrick , Moudrakovski Igor , Etter Martin , Friscic Tomislav , Dinnebier Robert E. , Lotsch Bettina
Published: September 2020

Covalent organic frameworks (COFs) have emerged as a new class of molecularly precise, porous functional materials characterized by a broad structural and chemical versatility, leading to a diverse range of applications. Despite the increasing popularity of COFs, fundamental aspects of their formation are poorly understood and profound experimental insights into their formation processes are still lacking. Here we use a combination of in situ X-ray powder diffraction and Raman spectroscopy to elucidate the reaction mechanism of mechanochemically synthesized imine COFs, leading to the observation of key reaction intermediates. Real-time monitoring provides experimental evidence of templating effects by the liquid additive for the subsequent pore formation and layer assembly. Moreover, the solid-state catalyst scandium triflate Sc(OTf)3 is revealed to be instrumental in directing the reaction kinetics and mechanism, resulting in products with crystallinity and porosity en par with solvothermally synthesized COFs. This work highlights the potential of mechanochemistry as a green synthetic route towards COF synthesis, and emphasizes the subtle interplay between choice of liquid additives, catalysts, and activation procedure.
Ultrathin Single-crystalline MgO (111) Nanosheets
Authors: Liu Pengxin , Abdala Paula M. , Goubert Guillaume , Willinger Marc , Copéret Christophe
Published: September 2020

Synthesizing high-quality two-dimensional nanomaterials of non-layered metal oxide is a grand challenge because it requires long range single-crystallinity and clean high-energy surfaces. Here, we report the synthesis of single-crystalline MgO(111) nanosheets via a two-step process involving the formation of ultrathin Mg(OH)2 nanosheets as precursor and their selective topotactic conversion upon heating under dynamic vacuum. The defect-rich surface displays terminal -OH groups, 3-coordinated O2- sites, low-coordinated Mg2+ sites as well as single electrons trapped at oxygen vacancies, that render MgO nanosheets highly reactive as evidenced by the activation of CO molecules at low temperatures and pressures, with formation of strongly adsorbed red-shifted CO and coupling of CO molecules into C2 species.
Chemical Tools for Study of Phosphohistidine: Generation of Selective τ-Phosphohistidine and π-Phosphohistidine Antibodies
Authors: Makwana Mehul , Dos Santos Souza Cleide , Pickup Barry T. , Thompson Mark J. , Lomada Santosh Kumar , Feng Yushi , Wieland Thomas , F. W. Jackson Richard , MUIMO Richmond
Published: September 2020

Non-hydrolysable stable analogues of τ-pHis and π-pHis have been designed using electrostatic surface potential calculations, and subsequently synthesized. The τ-pHis and π-pHis analogues (phosphopyrazole 8 and pyridyl amino amide 13, respectively) were used as haptens to generate pHis polyclonal antibodies. Both τ-pHis and π-pHis conjugates in the form of a BSA-glutaraldehyde-τ-pHis and BSA-glutaraldehyde-π-pHis were synthesized and characterized by 31P NMR spectroscopy. Commercially available τ-pHis (SC56-2) and π-pHis (SC1-1; SC50-3) monoclonal antibodies were used to show that the BSA-G-τ-pHis and BSA-G-π-pHis conjugates could be used to assess the selectivity of pHis antibodies in a competitive ELISA. Subsequently, the selectivity of the generated pHis antibodies generated using phosphopyrazole 8 and pyridyl amino amide 13 as haptens was assessed by competitive ELISA against His, pSer, pThr, pTyr, τ-pHis and π-pHis. Antibodies generated using the phosphopyrazole 8 as a hapten were found to be selective for τ-pHis, and antibodies generated using the pyridyl amino amide 13 were found to be selective for π-pHis. Both τ- and π-pHis antibodies were shown to be effective in immunological experiments, including ELISA, western blot, and immunofluorescence. The τ-pHis antibody was also shown to be useful in the immunoprecipitation of proteins containing pHis
The Peculiar Case of the Hyperthermostable Pyrimidine Nucleoside Phosphorylase from Thermus Thermophilus
Authors: Kaspar Felix , Neubauer Peter , Kurreck Anke
Published: September 2020

The poor solubility of many nucleoside and nucleobases in aqueous solution demands harsh reaction conditions (base, heat, cosolvent) in nucleoside phosphorylase-catalyzed processes to facilitate substrate loading beyond the low millimolar range. This, in turn, requires enzymes which withstand these conditions. Herein we report that the pyrimidine nucleoside phosphorylase from Thermus thermophilus is active over an exceptionally broad pH (4-10), temperature (up to 100 °C) and cosolvent space (up to 80% (v/v) non-aqueous medium) and displays tremendous stability under harsh reaction conditions with predicted total turnover numbers of more than 106 for various pyrimidine nucleosides. However, its use as a biocatalyst for preparative applications is critically limited due to its inhibition by nucleoside substrates at low concentrations, which is unprecedented among non-specific pyrimidine nucleoside phosphorylases.
Local Distortions in a Prototypical Zeolite Framework Containing Double Four-Ring Cages: The Role of Framework Composition and Organic Guests
Authors: Fischer Michael , Freymann Linus
Published: September 2020

Cube-like double four-ring (d4r) cages are among the most frequent building units of zeolites and zeotypes. In materials synthesised in fluoride-containing media, the fluoride anions are preferentially incorporated in these cages. In order to study the impact of framework composition and organic structure-directing agents (OSDAs) on the possible occurrence of local distortions of fluoride-containing d4r cages, density functional theory (DFT) calculations and DFT-based molecular dynamics simulations were performed for AST-type zeotypes, considering four different compositions (SiO2, GeO2, AlPO4, GaPO4) and two different OSDA cations (tetramethylammonium [TMA] and quinuclidinium [QNU]). All systems except SiO2-AST show significant deformations, with a pyritohedron-like distortion of the d4r cages occurring in GeO2- and GaPO4-AST, and a displacement of the fluoride anions towards one of the corners of the cage in AlPO4- and GaPO4-AST. While the distortions occur at random in TMA-containing zeotypes, they exhibit a preferential orientation in systems that incorporate QNU cations. In addition to providing detailed understanding of the local structure of a complex host-guest system on the picosecond timescale, this work indicates the possibility to stabilise ordered distortions through a judicious choice of the OSDA, which might enable a tuning of the material’s properties.
Mps2 links Csm4 and Mps3 to form a telomere-associated LINC complex in budding yeast
Authors: Fan Jinbo , Jin Hui , Koch Bailey A , Yu Hong-Guo
Published: September 2020

The linker of the nucleoskeleton and cytoskeleton (LINC) complex is composed of two transmembrane proteins: the KASH domain protein localized to the outer nuclear membrane and the SUN domain protein to the inner nuclear membrane. In budding yeast, the sole SUN domain protein, Mps3, is thought to pair with either Csm4 or Mps2, two KASH-like proteins, to form two separate LINC complexes. Here, we show that Mps2 mediates the interaction between Csm4 and Mps3 to form a heterotrimeric telomere-associated LINC (t-LINC) complex in budding yeast meiosis. Mps2 binds to Csm4 and Mps3, and all three are localized to the telomere. Telomeric localization of Csm4 depends on both Mps2 and Mps3; in contrast, Mps2’s localization depends on Mps3 but not Csm4. Mps2-mediated t-LINC complex regulates telomere movement and meiotic recombination. By ectopically expressing CSM4 in vegetative yeast cells, we reconstitute the heterotrimeric t-LINC complex and demonstrate its ability to tether telomeres. Our findings therefore reveal the heterotrimeric composition of the t-LINC complex in budding yeast and have implications for understanding variant LINC complex formation.
The Conflict Between Greece And Turkey In The Mediterranean Sea (International Maritime Law Study)
Authors: Yıldız Edanur
Published: September 2020

Turkey and Greece are again dragged into a new conflict in the East Mediterranean. Turkey and Greece vie for supremacy in the eastern Mediterranean. Turkey, for its part, indicated that Greece's claim to the territory would amount to a siege in the country by giving Greece a disproportionate amount of territory. This study aims to rethink the conflict between Greece and Turkey in the waters of the Mediterranean sea in the view of international maritime law. This study uses an empirical juridical approach. The Result of this research is Turkey does not ignore the Greece rights, Greece ignores the international law with its extended or excessive maritime claims. Greece tries to give full entitlement of the islands in Mediterranean and Agean. Whereas the effect Formula is applied by international courts.
A ACESSIBILIDADE NO DIREITO SOCIAL AO TRANSPORTE: CONCEITO NORMATIVO E SUA ESPECIFICAÇÃO CONCRETIZANTE.
Authors: Cidade Roberto Berttoni , Leão Júnior Teófilo Marcelo de Arêa
Published: September 2020

O direito ao transporte, garantido constitucionalmente pela Emenda Constitucional n. 90, a cada dia necessidade de melhor objetivação. Com isso, neste trabalho, via pesquisa bibliográfica e método hipotético-dedutivo, busca-se identificar as características de fundamentalidade, contextualização histórica de contemporaneidade. Bem como, dá-se relevo ao instituto de acessibilidade como requisito essencial voltada a garantir “facilidades”, “possibilidades” e “autonomia” ao cidadão com a renovação do paradigma histórico individualista para uma concretização coletivista de consumo dos direitos sociais de modo racional, sustentável e mais eficaz, garantindo adensamento à dignidade da pessoa humana, sem a pretensão de esgotamento da matéria.
Experiences and needs of patients with lower limb amputation in Saudi Arabia: a qualitative study
Authors: Abouammoh Noura , Aldebeya Wassim , Abuzaid Rabab
Published: September 2020

Background: The effect of amputation on the social and psychological well-being of patients has been established. However, the experiences and needs of amputees for the process of adjustment varies among individuals and cultures. Aims: This study aimed to explore the experiences and needs of lower limb amputees for social and psychological adjustment in Saudi Arabia, according to their own perspective. Methods: Thirteen patients with lower limb amputation (mean age 47 years) were recruited from a large rehabilitation centre in Saudi Arabia for participation in interviews. A focus group discussion with 6 amputees was followed by individual, semistructured interviews with 8 amputees (which included 1 from the focus group) between November 2017 and March 2018. Results: Patients’ needs and reactions prior to and after amputation were controlled by the surrounding support system. Hopelessness and depression, body image distress, religious attitude, and family and community support all contributed to shape the overall patient experience, including psychological and physical adjustment. Conclusions: Facilitating the re-integration of patients with lower limb amputation patients into their communities, as well as providing the required support system, is crucial to ensure a healthy adjustment process for amputees.
Determination of factors affecting the profitability variables by panel data analysis in the islamic banks: the case of Turkey
Authors: PARLAKKAYA Raif , AKTEN ÇÜRÜK Suna , KAHRAMAN Ümran , ŞEN Gülşah
Published: September 2020

Islamic banks, which operate on the profit and loss sharing basis, have an important role in the financial system in terms of the collected funds bringing into the real economy. Therefore, for a strong economic structure, the market share of Islamic banks in the financial system needs to increase. The profitability level of banks is one of the most important financial performance indicators. Determining the factors that affect profitability indicates which issues are vital.
The aim of this paper is to determine the factors that affect the profitability of participation banks operating in Turkey. In this context, panel data estimation methods were applied by using the data obtained from the financial statements (2006-2019) of three participation banks (Kuveyt Türk, Albaraka ve Türkiye Finans) and various macroeconomic indicators of the country. The most appropriate model was tried to be determined. In this study, the effect of capital adequacy ratio, bank size, credit risk, operational risk, operating effectiveness, inflation and GNP growth rate on return on assets (ROA) and return on equity (ROE) was analyzed. According to the results of the analysis, bank size, credit risk, operating effectiveness and inflation rates has an effect on ROA. Also, the effect of credit risk, operational risk, operating effectiveness and inflation rates on ROE is determined. Independent variables that do not have an impact on the profitability of banks are determined as capital adequacy ratio and growth. Also, according to the results of the analysis, it is possible to express that banks’ specific variables are more effective on the profitability of participation banks than macroeconomic indicators.
Ambassador Between Two Nations: Shakespeare in American Ideology
Authors: Jaroma Nicholas
Published: September 2020

The purpose of this thesis was to examine William Shakespeare’s role in American ideology. Utilizing the theoretical approaches of Louis Althusser, Michel Foucault, adaptation and appropriation theories, and Critical Race Theory, I argue that Shakespeare is an integral part of American history and culture by how his works factor into American ideologies, particularly within ideologies focusing on race and colonialism. Specific plays and Shakespeare’s texts are analyzed, and I also follow the literary history of Americans in response to these plays. My first chapter looks at the Revolutionary and early republic eras, with particular focus on John Adams, his son John Quincy Adams, and their analyses of Shakespeare’s works. The second chapter highlighted the Civil War era, and the Confederate sympathizer Mary Preston’s analyses of some of Shakespeare’s plays. The third chapter looked at how Shakespeare’s plays, particularly Julius Caesar, may have factored into President Abraham Lincoln’s assassination. My final chapter analyzed the early twentieth century, and how Shakespeare was used to push both racist and progressive ideologies. The conclusion looks at how Shakespeare and the Humanities are relevant in America in the twenty-first century. The conclusion of the thesis is that authoritative power, whether that be in government, or in the perception of the Author, must always be challenged if society is to progress.
Improving the Delivery of Enteral Nutrition in the Neurocritical Care Unit Through the Implementation of a Volume-Base Feeding Protocol
Authors: Walsh Joan
Published: September 2020

Neurocritical care patients receiving rate-based enteral nutrition (RBEN) consistently received less than their full prescription of enteral nutrition (EN) volume due to interruptions in feeding.
This study investigated the impact of the implementation of a volume-based feeding protocol (VBEN) on the percentage of prescribed volume of EN delivered over the course of patients’ neurocritical care unit (NCCU) length of stay.
Aim: The aim of this study was to better meet the nutritional needs of adult neurocritical care patients receiving nutrition through the enteral route. Methods: A retrospective pre and postimplementation chart review was conducted on adult
patients with age 18 or greater and less than 90 years with a neurological-related injury or disease process who had EN initiated and delivered for three or more days during their stay in NCCU.
Results: Despite no significant differences in characteristics or gastrointestinal complications between the groups, there was a significant increase in the percentage of prescribed EN volume delivered over the course of NCCU stay of 23.15% percentage points
in the VBEN group (M = 95.3%, SD 4.92) as compared to the RBEN group (M = 72.15%, SD 10.55, t(27, n=40) = 8.89, p
DESTEKLİ SIVI MEMBRANLAR İLE CR(VI) METAL KATYONUNUN ELEKTROMEMBRAN EKSTRAKSİYONU
Authors: ÇALIK Gamze , AYTAÇ Aylin , ALPOĞUZ Hamza Korkmaz
Published: September 2020

Hızla gelişen sanayileşme sonucunda ortaya çıkan çevre kirliliği ve özellikle ağır metal kirliliği son yıllarda hem Türkiye’nin hem de dünyanın ortak sorunu haline gelmeye başlamıştır. Bu problemi gidermek için türlü çözüm arayışına giren bilim insanları çeşitli membran prosesleri geliştirerek kirlilikleri bertaraf etme anlamında birçok çalışma yapmışlardır. Bu çalışmamızda destekli sıvı membran tekniği (SLM) kullanılarak elekromembran ekstraksiyonu (EME) olarak adlandırılan elektrodialitik yaklaşım sayesinde voltaj gücünden faydalanılmış ve iyonların ekstraksiyonu sağlanmıştır. Celgard 2500 ticari membrana faz transfer katalizörü olarak Aliquat 336 emdirilerek hazırlanan SLM (destekli sıvı membran) ile donör faz olan K2Cr2O7 (2x10-4 M ve 0,1 M HCl’de hazırlanmış) potsyum dikromat çözeltisinden, akseptör faz olan 0,01 M NaOH çözeltisine Cr (VI) taşınımı incelendi. Sırasıyla 10V - 20V - 30V - 40V - 50V ve 60V ve 0,3 amper akım altında yapılan 100’er dakikalık çalışmalarda krom(VI) transportu için optimum değer 50 volt 0,3 amper olarak belirlenmiş ve ayrıca aynı işlem 50 volt 0,3 amper de Celgard 2400 ticari membrana uygulanmış ve yapılan deneysel veriler karşılaştırılmıştır. Sonuç olarak Celgard 2500 destekli membranın verimi %54,73 olarak hesaplanırken Celgard 2400 membranın verimi ise %34,29 bulunmuştur.
IN-PLACE ANALYSIS OF OFFSHORE JACKET PLATFORM FOR DIFFERENT WAVE DIRECTIONS
Authors: BAIG MIRZA AAMIR , MAQBOOL UMER
Published: September 2020

Offshore jacket platforms are subjected to variety of forces during their life period. To resists all kinds of forces, the structural elements should be designed properly to have safety and economy. In order to fulfil this purpose, the structure should be analyzed with great care.

As the improvement of oil and gas moves into more profound water, in any case, taller stages with longer periods are fabricated that react all the more powerfully to extraordinary waves. Expectation of the dynamic reaction of such structures in extraordinary ocean states is in this way an essential plan thought. Standard waves have all their vitality lumped at a couple of particular frequencies and can, in this manner, cause wrong powerful enhancements, particularly if these frequencies happen to be near the regular frequencies of the structure. In any case, waves in the ocean are exceptionally sporadic and can be best depicted as directional range, which indicates the appropriation of wave vitality as for recurrence and heading, and is most appropriate for the examination of structure in recurrence space technique. For this situation the nonlinear drag is linearized and utilized in the Morison's condition. This guess is proper for the littler, operational sort waves considered in weariness counts, in light of the fact that the powers because of these waves are overwhelmed by the direct idleness part. Various kinds of investigations related with the coat stage ought to be performed to figure the reaction of the structure and measurement the components of the structure. Here an endeavor has been made to complete various examinations to comprehend the dynamic conduct of coat stages subject to different stacking conditions in various ecological conditions. Coat set up investigation was performed, both static and dynamic hypothetically fixed base stage.

With the ongoing imaginative thoughts of investigation utilizing programming, it is presently simpler for the seaward architects to do disentangled and sensible assessment of the static operational and extreme point of confinement state qualities of format or coat stages, which are exposed to different ecological conditions. The essential auxiliary parts of coat type seaward structures including topsides, coat, heaps and the encompassing soil are viewed as utilizing SACS programming various types of investigations identified with coat stage according to API code prerequisite.