bluuebunny/crossref_metadata_2025 huggingface dataset:
Bemerkungen zum frühkaiserzeitlichen Münzverkehr der Ungarischen Tiefebene. Republikanische Und frühkaiserzeitliche Münzen aus dem Jászság (Kom. Szolnok/U)
Authors: Prohászka Péter
Published: December 2019

Although various works had been dealt with Roman money circulation of the Great Hungarian Plain some phenomena remained undiscovered for the research. This paper deals with republican and early imperial mints came to light in the territory of Szolnok County. The Jászdózsa hoard with its 114 pieces of Roman republican and early Roman period denars from P. Sulla (151 B.C.) to Emperor Nero (AD 64–68) belongs here. The Roman coins had appeared in large numbers only since the first century AD in the Great Hungarian Plain. The republican coins are very rarely represented, though they are very common in Transylvania. From the Zagyva mouth area to the river Tisza, and from the territory of the Jászság some hoards and scattering finds are known. It is difficult to interpret the circulation of these coins due to the lack of written sources and archaeological finds. Because of the Aurei the role of Roman politics should also be taken into consideration. Which gentes had lived in the territory of the Jászság and what role they had played in the relationship system of the Carpathian Basin we have rarely any information about. The hoard of Jászdózsa was probably hidden at about the Year of the Four Emperors (AD 69) or shortly thereafter.
Hermannstadt und die Stadtarchäologie
Authors: Ţiplic Maria Crîngaci , Ţiplic Ioan Marian
Published: December 2019

Sibiu and the urban archaeology. During the last two-three decades the urban archaeology in Transylvania has pointed towards a visible progress. In the cities of Alba Iulia, Bistriţa, Braşov, Baia Mare, Dej, Cluj-Napoca, Lugoj, Orăştie, Oradea, Sebeş, Sfântu Gheorghe, Sibiu, Sighişoara, Timişoara, Târgu Mureş and Turda archaeological investigations were carried out. In Sibiu, the first preemptive archaeological excavation took place in 1970 and focused upon the house and residence of the town's former mayor, Altemberger. Afterwards any archaeological campaign has been stopped for more than a decade. It was in 1983 that such endeavors have made a new start – once again in the respect to the same gothic historical civil monument. In Sibiu this was a year that is to be regarded as the beginning of scientific and salvage archaeological research, at an institutional level. Ever since then up until 2016 more than hundred archaeological interventions have taken place in Sibiu. After more than three decades of urban archaeological research and collecting information we must emphasize the need for centralizing, for developing a chronological repertoire, a mapping of archaeologically investigated objects, for listing the involved archaeologists, the results and various interpretations, the numerous papers, studies and monographs, as well as their abstracted interpretation.
There’s a lithium battery in your future
Authors: Berkowitz Rachel , Aurbach Doron
Published: December 2019

Battery technology has come a long way since September 1899, when Ferdinand Porsche’s electric powered car won its first road race. The “Egger-Lohner electric C.2 Phaeton” carried a Tudor brand lead-acid battery that weighed 500 kg and propelled the 1350-kg vehicle with 3 hp (2.2 kW for 3–5 h) for 80 km.
Combining classroom and workplace teaching to deliver physical examination teaching: A theoretical approach
Authors: Omar Adhnan
Published: December 2019

This article was migrated. The article was not marked as recommended. Medical educators work to better prepare students for clinical work by constantly evolving medical curricula. The 'integrated curriculum' was designed to be repetitive but progressive with the aim to reduce disconnect between basic science and clinical practice. The problems arose when classroom teaching and clinical exposure happen as isolated events rather than being part of the same learning experience. This piece presents a theoretical overview of the benefits and drawbacks of combining classroom and workplace teaching to deliver physical examination teaching. The Adult learning theory proposes that this methods of teaching would promote their interest in meaningful learning. Furthermore, combining cognitivism and constructivism approaches to create and then build on schemata offers an effective way to transfer learning. There is however recognition of the limitations that primarily focus of the individuality of students with which teachers can struggle to respond.
KCl flux suppresses surface recombinations of hematite photoanode for water oxidation
Authors: Cao Huanhuan , Si Wenping , Guo Wenlei , Zhang Tao , Han Yonghuan , Hou Feng , Liang Ji
Published: December 2019

Hematite is a promising photoanode for solar water splitting because of its favorable bandgap, excellent chemical stability and low cost. However, it suffers from both severe bulk and surface-charge recombinations, resulting in photoactivities much lower than the theoretical value. In this work, a facile new strategy is proposed by annealing hematite in the presence of potassium chloride (KCl) flux at 800°C. The photocurrent density of the annealed hematite, denoted ‘KCl-hematite’, increases from 0·34 mA/cm2 for pristine hematite to 0·54 mA/cm2 at 1·23 VRHE and further to 0·90 mA/cm2 after cobalt–phosphate (Co-Pi) deposition. Moreover, the photocurrent onset potential of KCl-hematite shows a cathodic shift of 120 mV compared with that of pristine hematite. It is demonstrated that potassium chloride flux can enhance the crystallinity and orderliness of hematite on the surface, reducing surface recombinations. This facile strategy by a flux offers a new insight to passivate surface recombinations of photoelectrodes and can be easily extended to other materials to enhance their photoactivities.
Amenazas y conflictos híbridos: características distintivas, evolución en el tiempo y manifestaciones preponderantes
Authors: Bartolomé Mariano
Published: December 2019

Dentro del campo de análisis de la seguridad internacional contemporánea, ocupa un lugar de importancia la “hibridación” de los conflictos armados y las amenazas transnacionales, cuestión que demanda la constante atención de los especialistas. El presente artículo aborda tanto la amenaza que constituye un actor que plantea modos de combate híbridos como la resultante de la combinación sinérgica de al menos dos amenazas diferentes, que pueden darse de manera autónoma. Se presenta un panorama actualizado sobre el tema, que refleja su estado del arte, incluyendo versiones ajenas a Occidente. El primer objetivo consiste en establecer dónde radica la singularidad de los conflictos híbridos respecto a las formas precedentes de contienda armada, subsanando así los inconvenientes que plantean tanto un empleo poco riguroso de los términos como cierta proliferación semántica. El segundo objetivo, complementario del primero, apunta a identificar los formatos más relevantes que adoptan las amenazas híbridas en la actualidad. Las conclusiones indican si se registra la presencia de conflictos y amenazas híbridas en América Latina, y en caso afirmativo, cuáles son sus manifestaciones, así como el grado de preparación de los Estados frente a ellas.

Abstract

In the field of contemporary international security, the “hybridization” of armed conflicts and transnational threats has a high level of priority, demanding constant attention from specialists. This article analyzes threats coming from actors that choose hybrids ways of warfare, and also the combination of at least two different and autonomous threats. An updated framework about this issue, which reflects the state of the art, including nonwestern views, is presented. The first objective is to identify the singularity of hybrid conflicts, and its differences with previous forms of armed conflicts, fixing the problems produced both by an unrestricted use of concepts and certain semantic proliferation. The second objective, which complements the former, seeks to identify the most common expressions of hybrid threats in today´s international relations framework. The conclusions address if hybrid conflicts and threats are present in Latin America and, in an affirmative case, what is the degree of preparation of the States to fight these problems.
Anti-iNKT MicroBeads Isolation protocol v1
Authors: N Shah Ajit , Hatano Rachel
Published: December 2019

isolation of 6b11 positive cells
Virtual assistance information model for public services
Authors: Baranchuk Vladislav A.
Published: December 2019

Currently, the world and Russia are rapidly developing the direction of developing virtual assistants. This is primarily due to the demands of business, the state and the population for this product, as well as the development of technologies capable of high-quality implementation of this product. Offers on virtual assistants for business and the public exist in large numbers: Google Assistant, Microsoft Cortana, Siri, etc. At the same time, there are no ready-made solutions for state needs in the market. The task of navigating public services today is the most relevant and relevant for the public sector. Solving this problem using a virtual assistant will save billions of rubles a year across the country. The article proposes an information model for the implementation of a virtual assistant for navigating public services. The basis of the intelligence of the developed virtual assistant is made up of artificial neural networks. The developed virtual assistant information model is implemented in the VIka software product. The trial operation of VIka takes place on the website of the administration of the Khanty-Mansiysk Autonomous Okrug Yugra, located at https://vi.admhmao.ru/chat/new.php. To date, VIka can help navigate services in 10 areas, such as healthcare, utilities, a line to kindergarten, etc.
24-hour blood pressure profile analysis and comorbid pathology in postmenopausal female ­patients not receiving antihypertensive therapy
Authors: Izmozherova N V , Popov A A , Getmanova N A
Published: December 2019

Aim. Assessment of ambulatory blood pressure monitoring data depending on the Charlson comorbidity index in postmenopause.

Methods. A cross-sectional study included 129 outpatients who did not receive medical treatment for hypertension. Median age was 58.5 (54.062.0) years, postmenopause duration 9 (4.012.0) years. Investigation included medical history registration, physician examination by an internist, anthropometry with measurement of body mass, height with further body mass index calculation. Comorbid conditions were diagnosed according to current clinical guidelines. All females had ambulatory 24-hour blood pressure monitoring. Based on Charlson comorbidity index, the subjects were divided into groups with moderate comorbidity (Charlson index 2, group 1) and high comorbidity (Charlson index 2, group 2).

Results. Females from group 2 were significantly older, had a longer duration of postmenopause and the severity of menopausal symptoms, higher body mass index values, functional limitations due to osteoarthritis, higher maximum and average 24-hour, average daily and average night systolic blood pressure levels as well as time index. No differences were revealed in the prevalence of females with night increase or absence of sufficient decrease of blood pressure at night. The absence of antihypertensive treatment in multimorbid postmenopausal females was associated with significant menopausal symptoms persistence.

Conclusion. Blood pressure monitoring in multimorbid females can reveal higher average daily values of systolic and diastolic blood pressure, higher variability during 24 hour of systolic blood pressure and greater index of time of systolic blood pressure, which can be considered as a cardiovascular disease progression predictor; uncontrolled hypertension and persistence of neurovegetative symptoms of menopausal syndrome may be the markers of a higher risk of premature death compared to the assessment by Charlson index score.
Features of managing patients with gastrointestinal bleeding in resuscitation and intensive care units
Authors: Bayalieva A Zh , Zefirov R A , Yankovich Yu N
Published: December 2019

Emergency hospital doctors very often encounter cases of gastrointestinal bleeding. Known causes of such bleeding are peptic ulcers of the stomach and duodenum and esophageal varices in portal hypertension. But there are cases of gastrointestinal bleeding, when the diagnosis is not easy to establish, treatment is carried out symptomatically and fatal dangers for the patient are often underestimated. Bleeding is often massive and difficult to assess in terms of volume as blood is in the gastrointestinal tract and only changes in hemodynamics and blood tests can serve as indirect indicators of blood loss. Carrying out intensive care and resuscitation measures simultaneously with endoscopic and surgical methods to stop bleeding determine a high risk and dramatic situation. On the background of hypocoagulation syndromes associated with the use of anticoagulants and antiplatelet agents, the course of these syndromes is significantly complicated. A major contribution to the adverse outcome of the disease is brought by severe concomitant diseases and old age. Intensive care for this category of patients requires an individual approach, taking into account the underlying disease and the cause of bleeding, as well as comorbidities. Endoscopic methods of vascular coagulation are the main ways for diagnosing and stopping bleeding, but in extreme cases urgent surgical intervention is necessary. Patients require treatment in multidisciplinary clinics, where there is an expanded diagnostic service, endoscopic service, departments of abdominal and thoracic surgery, transfusion and resuscitation departments and intensive care with extended options for replacement therapy of vital organs. The article provides a review of the causes, diagnosis and methods of intensive treatment of upper gastrointestinal bleeding from esophagus and stomach in MalloryWeiss and Boerhaave syndromes.
Immune structures of the greater omentum and their role in cancer metastasis
Authors: Zlatnik E Yu , Nepomnyashchaya E M , Zhenilo O E , Nikitina V P , Verenikina E V , Nikitin I S
Published: December 2019

Omental malignant metastases are one of the challenging issues in oncology. The article provides a review of recent studies on the structure and functions of immune compartments of the greater omentum and their characteristic features that promote or inhibit tumor dissemination. The cellular composition of lymphoid nodules and milky spots is described, and functional and phenotypic properties of macrophages and lymphocytes are shown. Unique subpopulations of immunocompetent cells typical of this particular organ, as well as produced cytokines, are characterized. Particular attention is paid to the visceral adipose tissue surrounding immunocompetent cells and its effect on their functions. Analysis of the literature data has revealed a dual role, i.e. both protective and immunosuppressive one, of lymphoid structures of the greater omentum. The former is apparently associated mainly with a response to bacterial pathogens, while the latter is realized in cancer metastasis. The article focuses on immunological mechanisms that create local conditions for the growth and development of metastases, in particular, proinflammatory cytokines, chemokines, growth factors secreted by immune, tumor and mesothelial cells, and on the importance of the surrounding visceral adipose tissue for this process. The multidirectional prognostic significance of some local cellular and cytokine factors in cancer metastasis to the omentum and peritoneum is demonstrated. Possible approaches to treatment involving immunotherapy should be aimed at both elimination of tumor cells and overcoming the immunosuppressive environment. In this regard, reprogramming of macrophages, correction of hypoxic microenvironment, and the search for new control points seem promising.
Social aspects of prevention of male and female infertility
Authors: Gil'manov A A , Akhmetzyanova G Z , Khisamutdinov A N , Shakirzyanova S R , Shakirzyanova K R
Published: December 2019

Aim. To evaluate the degree of awareness of the managable social risk factors for prevention of male and female infertility and to suggest preventive measures.

Methods. We conducted a survey among 140 medical students and 140 students of other higher educational institutions. The majority of students in both groups who participated in the survey were aged 21 to 23 years (60%). There were 20 questions in the questionnaire. They were of the following type: Do you know that ... can lead to infertility? Instead of the dots there were certain risk factors. Students answered the question yes or no.

Results. According to the results of the survey, medical students are much better aware of risk factors of infertility and its prevention. Most of the medical students and students of other institutions (72 and 73% respectively) plan to be parents already at the age of 23 to 28 which is in the upcoming decade so they have to think about infertility prevention now.

Conclusion. Awareness of infertility risk factors especially among non-medical students is quite low so spreading the information about prevention of the diseases leading to infertility among youth is necessary.
Risk factors in a health model of nursing stuff
Authors: Kasimovskaya N A
Published: December 2019

Aim. To study the behavioral trajectory of the lifestyle of students of medical colleges who studied in 20152016 and a health model formed by them.

Methods. Using a sample (n=400) selected by a simple random method, the lifestyle and health model of students of medical colleges in Moscow in 20152016 were studied by sociological method based on descriptive statistics, correlation-regression and factor analysis.

Results. Analysis of lifestyles of the students of medical colleges revealed the following behavioral risk factors: alcohol consumption (55.3%), eating improperly (54.5%), smoking (38%), improper sleep regimen (35%), and low physical activity (30%). The analysis of the health model showed that such risk factors as smoking, improper diet, and incorrect sleep regimen are assessed by the students in medical colleges as harmful, and with the increasing prevalence of the factor among the students, the number who consider them harmful will increase, while such factors as alcohol consumption and low physical activity are not considered by the students as harmful and with the increasing prevalence of this factor among the students, the number of students who consider them as risk factors will decrease.

Conclusion. Among the students of medical colleges, the negative behavioral trajectory of a lifestyle formed at the beginning of the 21st century, including smoking, drinking alcohol, unhealthy diet, improper sleep, and low level of physical activity, has been preserved; the developed health model shows that students consider smoking, malnutrition and improper sleep risk factors, and factors such as alcohol consumption and low activity are not considered harmful.
Investigating the correlation between magnetic Barkhausen noise emission and the fatigue life of shot-peened AISI 4140 steel
Authors: Çalışkan S , Gür C Hakan
Published: December 2019

The performance of engineering components under conditions of fatigue can be improved by shot peening. The location and magnitude of the highest residual compressive stress, the depth of the compression zone and the stability of the residual stress state during cyclic loading are critical
parameters for maximum utilisation of the advantageous influence of shot peening on fatigue performance. For accurate assessment of fatigue lifetime, residual stresses should be considered because they are algebraically summed with applied stresses. Therefore, the development of a non-destructive
testing (NDT) method that has the ability to rapidly monitor surface residual stresses has industrial importance when verifying the achievement of the design goals of shot peening. The utilisation potential of the magnetic Barkhausen noise (MBN) technique in shot peening of ferromagnetic steels
includes automated sorting of the components and measurement of surface residual stress. This study aims to establish the correlation between MBN emission and the fatigue life of shot-peened AISI 4140 steel.
Leer en Psicología ¿Qué dicen los estudiantes al ingresar y al finalizar el primer año?
Authors: Villalonga Penna Maria Micaela
Published: December 2019

Las percepciones de los estudiantes nóveles en relación a lo que se lee y su participación en comunidades disciplinares son dimensiones de singular importancia al desarrollar procesos de lectura con fines académicos. Desde esa perspectiva el presente artículo tiene como propósito analizar las concepciones de los estudiantes del primer año de los Programas Académicos de Psicología en relación a qué se lee al iniciarse y al finalizar la carrera. Con base a un enfoque cualitativo se procede a estudiar la categoría Lectura con intencionalidad formativa Disciplinar como constructo emergente; La recolección de información se realizó a partir de entrevistas en profundidad a los estudiantes en dos oportunidades una, al iniciarse el ciclo lectivo y otra, antes de finalizar el mismo. Entre los principales resultados destaca que los estudiantes con alto rendimiento logran construir conocimiento sobre las clases de texto y los tipos discursivos, así como también evidencian apropiación de los géneros académicos que se leen en esta comunidad disciplinar. Se concluye en que existen diferencias importantes en cuanto a las percepciones que obtienen estudiantes con calificaciones medias o altas en los parciales de las asignaturas en relación a los que han obtenido bajas calificaciones.
Representación literaria del cambio perturbador sonoro en la novela Mene de Ramón Díaz Sánchez
Authors: Montero Morillo Alicia Cecilia , Quintero Suárez Mayli Mariam
Published: December 2019

El estudio analiza en la novela Mene (1936) de Ramón Díaz Sánchez, la representación de los cambios en los sonidos ambientales, producto de la explotación petrolera y de su impacto en los habitantes de una región Venezolana. El narrador utiliza el sonido como eje portador de los cambios drásticos generados por la naciente industria, valiéndose de imágenes auditivas simples, símiles y metáforas. La construcción de conceptos metafóricos se aborda desde la teoría de Lakoff y Johnson (1980). La metodología es de corte analítico documental donde se devela el tratamiento de las categorías emergentes por parte del autor. Los resultados destacan como un grupo de metáforas se desarrollan a partir de un concepto metafórico particular, derivado de un modo de comprensión del mundo proveniente de la experiencia. Se concluye que el autor a través de la obra, expresa formas complejas de pensamiento sistémico, donde las figuras literarias representan constructos que conducen el encadenamiento lógico de las ideas

Palabras claves: Petróleo, Metáforas, Imágenes auditivas, literatura venezolana.
ELECTROMAGNETIC LATTICE “INVISIBILITY” OF THE PHOTON CRYSTAL MADE OF MAGNETODIELECTRIC SPHERES IN THE FORM OF OCTAHEDRON of octahedron
Authors: KOZAR Anatoliy
Published: December 2019

Solution and analysis of a problem on electromagnetic lattice "invisibility" of the photon crystal made of magnetodielectric spheres in the form of octahedron with a cubic crystal lattice are presented
Analysis of prescription pattern of anemia in pregnancy: an observational, cross-sectional study
Authors: Amrale Prasad R. , Ahire Sagar S. , Vairage Reshma M.
Published: December 2019

Background: Anemia is a major health problem that affects 25% to 50% of the population of the world and approximately 50% of pregnant women. This research on the use of prescription medicines in anemia during pregnancy remains critically important. Prescribing patterns of the drug in the pregnant women include age, trimester, gravid condition, US-FDA risk category, WHO core indicators.Methods: A prospective, cross sectional observational multicentric study was conducted in outpatient and inpatient departments of Indira Gandhi Hospital and Civil Hospital in Nasik, for period of 6 months. Ethical approval was taken prior to study from Independent ethics committee. A total of 197 patients were enrolled in the study. Inform consent form was obtained from the patients. After studying them; statistical analysis were done and result and conclusion were drawn.Results: Out of 197 women’s prescriptions, the average number of drug per prescription was 2.14. 27.28% drugs were prescribed there brand name and 72.72% by generic name. Iron, folic acid and calcium were prescribed to all pregnant women. The majority of the patients were prescribed category A and category C drugs. No patients were given category X drug.Conclusions: Nearly all prescription showed a prescribing practice for writing prophylactic iron and folic acid therapy in all pregnant women. No women was prescribed category X drug. Most of the drug prescribed in generics and thus, prescription pattern of our study set a fine example of prescribing behaviour.
Quality of life of alcohol dependent patients attending a deaddiction centre in Kannur district
Authors: Ratheesh R. , Mohandas Bindu , Venugopalan P. P. , Sarada A. K. , K. Suprej , V. K. Sobith
Published: December 2019

Background: Quality of life (QOL) is individuals' perceptions of their position in life. QOL of alcohol dependent patients is an area that has received relatively less attention compared to other alcohol related problems.Methods: A deaddiction centre based cross sectional study was done on 370 individuals using a predesigned questionnaire during the period of 2012-2013. The data was analyzed using SPSS version 17. Spearman’s rank correlation test was used to find association between the study variables.Results: The mean age of the study subjects was 38.08±8.46 years. The mean duration of drinking was 12.62±7.47 years. The overall score of the QOL and the perceived health in alcohol dependent patients was 3.19±0.89 and 3.01±0.98 respectively. The mean of the transformed scores of physical, psychological, social and environmental domains are 69.12±12.82, 57.84±12.81, 58.52±17.05, 68.62±10.23 respectively. Statistical analysis of age with physical, environmental and social domains showed a significant negative correlation; literacy status with QOL, perceived health, physical, psychological, social and environmental domains showed a significant positive correlation; socio economic status with QOL and psychological domain showed a significant positive correlation; duration of drinking with QOL, perceived health, physical and psychological domain showed a significant negative correlation.Conclusions: Harm from alcohol use is a major public health problem. Reducing the level of social and health harms from alcohol requires preparation and planning.
Thoracic limb salvage by fibular free flap
Authors: Ruiz Rodrigo Banegas , Valderrama Treviño Alan I. , Gómez Mendoza Francisco Fabián , Mendoza Aceves Rodrigo A. , Hernández Rigoberto Román , Alba Ismael Vejar , Verdejo Fernando Gómez , Rivas Montero José Antonio , López Karolina Ortega , Caprielova Yuri Jiménez , Arteaga Leonel Dalain Hernández , Ortega Emilio Pérez , Mera Baltazar Barrera
Published: December 2019

The treatment of most fractures of the ulna and radius is usually performed by anatomical reduction and internal fixation, when damage is extensive and local soft tissue cannot provide a complete wound coverage, locoregional flaps present a suitable reconstructive benefit. A 35-year-old male patient suffered an exposed diaphysio-metaphyseal fracture with multi-fragmented distal radius. The patient was evaluated during a 10-day period at the National Institute of Rehabilitation, where the osteosynthesis material and a severe infectious process with necrosis were identified. Necrosectomy of the posterior compartment and removal of the osteosynthesis material was performed, a skin defect of approximately 22x16 cm was observed with a bone gap of 6 cm of radius and ulna. a fibula-free flap is placed to correct the skin defect and an external fixative used for bone alignment. The fibular free flap presents an excellent therapeutic alternative in the resolution of bone gaps with extensive skin defect. Whenever a trained microsurgery team is available, current scales of limb injury should be considered but not utilized for therapeutic approach, always trying to shift amputation as the first option, to the very last one of them.
Use of diclofenac suppositories in pain management in acute fissure in ano in outpatient department care
Authors: Deherkar Juthikaa Abhijit
Published: December 2019

Background: Per anal diseases and the pain management in such cases have always been a problematic solution for surgeons. There are various pain management methods for per anal cases, however we wanted a cheaper yet effective way and patient friendly method for pain management where no expertise would be required, hence we opted to see results of diclofenac suppositories which were easily available, patient could insert it without anyone’s help or assistance and hence need not be hospitalized for any intravenous analgesics.Methods: A study was conducted over 2000 cases over a span of 6 years in a tertiary centre. A control group A of 1000 patients was made where, oral (tablet diclofenac) plus local analgesics (xylocaine gel) were opted for whereas the other group B of 1000 patients was treated with diclofenac suppository 100 mg twice a day with glycerin as lubricant at anal verge. The pain score was noted in both the groups. All acute fissure in ano cases, we included in this study.Results: The pain score of the group B cases was much lower than the group A cases, and also the duration of results acquired was much lesser than group A.Conclusions: Diclofenac suppository 100 mg twice a day proved to be an excellent pain management method for acute fissure in ano cases in outpatient department care.
Study of hematological profile in patients with chronic kidney disease
Authors: Panduranga Gautam , Perla Ugendhar
Published: December 2019

Background: Chronic Kidney Disease (CKD) with its high prevalence, morbidity and mortality, has become an important public health problem. The incidence and prevalence of CKD is increasing worldwide, including India. CKD is associated with a variety of hematological abnormalities, include anaemia, infections and bleeding diathesis. Anaemia is the most consistent hematological abnormality and is associated with poor quality of life and poor cardiovascular outcomes.Methods: A hospital based cross-sectional observational study was done to detect the prevalence of haematological abnormalities, correlation of anaemia with CKD stage and evaluation of iron deficiency. Newly diagnosed CKD (stages 3 to 5) patients were included in this study. Presence of anaemia (Hb%, haematocrit, MCV, peripheral smear), iron deficiency (TSAT, serum ferritin), thrombocytopenia, leucocyte count and coagulation abnormalities (PT, APTT) in different stages of CKD were studied.Results: All the subjects in study group had anaemia which was normocytic and normochromic and of moderate degree in most patients. The severity of anaemia progressed with stage of the disease. Iron deficiency was significantly prevalent (52% in the study population, with transferrin saturation (TSAT) <20%). WBC count was not significantly altered. There was mild thrombocytopenia in a few patients. Bleeding time or other in vitro tests of platelet function were not measured. The coagulation parameters, PT and APTT, were not significantly altered.Conclusions: All CKD patients should be screened for iron deficiency anaemia for its early treatment and to decrease morbidity.
Study of sociodemographic factors affecting outcome of babies admitted in neonatal care unit
Authors: Kawale Suchita N. , Shinde Manjusha A. , Shinde Prashant S.
Published: December 2019

Background: A country needs sound epidemiological information to prioritize, plan and implement the public health care system effectively. Outcome data from hospitalized patients reflect the causes of major illnesses and care seeking behaviour of the community. Thus, we felt the need to conduct this study at our hospital to assess the socio-demographic factors affecting outcome of babies admitted in neonatal intensive care unit.Methods: The present study was a hospital based observational descriptive study. The study was undertaken in neonatal intensive care unit (NICU) of department of paediatrics of tertiary care centre. The study period was from January 2013 to December 2013 i.e. total period of one year.Results: Among 1050 total neonatal admissions 601 (57.29%), were from rural area and 449 (42.70%) were from urban area. Multinomial regression analysis reveals that socio-demographic factors like age of mother, parental intake of tobacco alcohol in any form, socioeconomic class IV, in born place of delivery, occupation and education of father, low birth weight and male sex of baby affects the outcome of babies.Conclusions: Cure rate in NICU admissions was 69% which may be due to available speciality staff and logistics. Taking this into account, 40 bedded NICU in tertiary care hospital seemed to be essential and sufficient.
Patient and health provider factors affecting diagnostic delays of pulmonary tuberculosis in Jabalpur district of Madhya Pradesh, India: a cross-sectional study
Authors: Sahu Rupesh , Verma Prashant , Kasar Pradeep K.
Published: December 2019

Background: Delay in diagnosis of pulmonary tuberculosis (PTB) causes patients to have more severe disease, more complications and lead to higher mortality with disease spread. The aim of the study was to estimate patient proportion having delayed diagnosis of PTB and to estimate patient’ and health providers’ delay and associated factors.Methods: This cross sectional study was conducted on sample of 135 new sputum positive PTB patients from nine designated microscopy centres of Jabalpur district. Data collected on modified world health organization questionnaire. The criterion for defining delay was formulated keeping in mind the Revised TB Control Programme algorithm for diagnosis of PTB in PTB suspects. Mann Whitney U and Kruskal Wallis tests were used (α=5%).Results: Mean age was 33.87 (14.3) years. Males constituted 66.7%. Proportion of diagnostic delay was 87.4%. Median patient and health care personnel (HCP) interval were 39 days (IQR 22-75) and 34 days (IQR 12-79) respectively. Factors significantly associated with patient delay were poor knowledge about TB, smoking, symptoms perceived non serious, first action with symptom onset, and mode of transport patient used to reach the nearest public health facility. Stigma didn’t affected patient interval. Factors significantly associated with health providers’ delay were first consultations with; a non-formal HCP, private health facility, non-allopathic practitioner; consultation with multiple HCP’s; living more than half an hour away from public health facility.Conclusions: Unacceptable high delay in diagnosis, more from patient side. More attempts at increasing awareness are needed.
Directionality of kinesin motors.
Authors: Kasprzak Andrzej A , Hajdo Łukasz
Published: December 2019

Kinesins are molecular motors that transport various cargoes along microtubule tracks using energy derived from ATP hydrolysis. Although the motor domains of kinesins are structurally similar, the family contains members that move on microtubules in opposite directions. Recent biochemical and biophysical studies of several kinesins make it possible to identify structural elements responsible for the different directionality, suggesting that reversal of the motor movement can be achieved through small, local changes in the protein structure.
Binding of the basic fibroblast growth factor (bFGF) by soluble components of human umbilical cord.
Authors: Sobolewski Krzysztof , Bańkowski Edward , Pałka Jerzy , Jaworski Stefan
Published: December 2019

Pre-eclampsia, the most common pregnancy associated syndrome, is connected with remodelling of extracellular matrix of the umbilical cord tissues. Since the fibroblast growth factor (FGF) is known to be a stimulator of collagen and glycosaminoglycan biosynthesis, one may expect that it plays an important role in such a remodelling. Studies performed on the umbilical cords of 10 control and 10 pre-eclamptic newborns demonstrated that both the umbilical cord arterial wall and Wharton's jelly contain FGF mainly in complexes with the components of different molecular mass. Pre-eclampsia is associated with a decrease of endogenous FGF-binding by soluble high molecular mass components of the umbilical cord. It is suggested that FGF released from these complexes may be actively bound by fibroblasts of the umbilical cord, stimulating them to produce collagen and sulphated glycosaminoglycans.
High performance liquid chromatography and photodiode array detection of ferulic acid in Rubus protoplasts elicited by O-glycans from Fusarium sp. M7-1.
Authors: Nita-Lazar Mihai , Chevolot Lionel , Iwahara Shojiro , Takegawa Kaoru , Furmanek Aleksandra , Lienart Yvette
Published: December 2019

So far only little data have been available concerning the eliciting capacity of well defined glycan molecules isolated from plant pathogens. This study brings new information about changes in plant cells caused by fungal pathogens. Sugar fractions derived from glycoproteins isolated from the fungus Fusarium sp. M7-1 have been tested here as signaling molecules. The ability of three O-glycan fractions (named in this work inducer I, II, III) to trigger responses in Rubus protoplasts has been examined. It was found that inducer III was the most efficient as it elicited changes in the levels of phenylpropanoid pathway intermediates in relation to phenylalanine-ammonia lyase (PAL) activation.
Lipopolysaccharides from Mesorhizobium huakuii and Mesorhizobium ciceri: chemical and immunological comparative data.
Authors: Choma Adam
Published: December 2019

Lipopolysaccharides of two Mesorhizobium species of different host specificity were compared: M. huakuii and M. ciceri. M. huakuii sp. was represented by five strains with special consideration of M. huakuii IFO 15243(T). SDS/PAGE profiles revealed that all M. huakuii LPS preparations contained low molecular mass fractions (LPS-II) of the same molecular size. All of lipopolysaccharides contained high molecular mass fractions (LPS-I). However, the high molecular mass fraction from each strain possessed an individual molecular size distribution pattern. The crossreactivity of blotted lipopolysaccharides with rabbit polyclonal antibodies against Mesorhizobium huakuii IFO 15243(T) whole bacteria indicated the presence of common epitope(s) within the investigated Mesorhizobium huakuii strains. Moreover, LPS from M. huakuii S52 also reacted with anti M. ciceri HAMBI 1750 serum showing that there are epitopes common for different mesorhizobial species. LPS isolated from Mesorhizobium huakuii strain IFO 15243(T) contained neutral sugars: L-6-deoxytalose, L-rhamnose, D-galactose and D-glucose, aminosugars:D-quinovosamine, D-glucosamine, D-2,3-diamino-2,3-dideoxyglucose and D-galacturonic and D-glucuronic acids. In the LPS preparation, fatty acids typical for Mesorhizobium strains were detected. 3-Hydroxydodecanoic, 3-hydroxy-iso-tridecanoic, 3-hydroxyeicosanoic, 3-hydroxyheneicosanoic and 3-hydroxydocosenoic acids were the major amide linked fatty acids, while iso -heptadecanoic, eicosanoic, docosenoic, as well as 27-hydroxyoctacosanoic and 27-oxooctacosanoic acids were the dominant ester linked fatty residues.
ITINERÁRIO TERAPÊUTICO DAS FAMÍLIAS DE CRIANÇAS COM MICROCEFALIA
Authors: Souza Manuela De Jesus , Morais Aisiane Cedraz , Lima Isamara De Souza , Mascarenhas Jéssica Souto , Lima Maricélia De Maia , Amorim Rita Da Cruz
Published: December 2019

Objetivo: analisar o itinerário terapêutico de famílias de crianças com microcefalia no interior da Bahia. Método: estudo qualitativo, descritivo-exploratório, realizado no Centro de Apoio aos Pais de Crianças acometidas pela Síndrome Congênita associada ao Zika Vírus no interior da Bahia. Participaram nove familiares de crianças cadastradas nesse serviço. Os dados foram coletados de julho a novembro de 2017, por meio de entrevista semiestruturada, e analisados por meio da Análise de Conteúdo de Bardin. Resultados: emergiram três categorias: Itinerário para o Diagnóstico, Itinerário Terapêutico para acompanhamento da criança com Microcefalia e Suporte Social para o cuidado da criança com microcefalia. Conclusão: o itinerário terapêutico de famílias de crianças com microcefalia no interior da Bahia destacou o sistema profissional e incluiu a dificuldade para o diagnóstico, a rede social e a espiritualidade, que apareceram como importantes suportes a esses familiares para o cuidado cotidiano, e valorização das crenças e cuidado cotidiano das famílias, que permitiram maior vínculo com a equipe de saúde.
Descritores: Apoio Social. Família. Cuidadores Familiares. Cuidado da Criança. Microcefalia.
Do mito do centro mediado ao mito do big data: reflexões do papel da mídia na ordem social
Authors: Couldry Nick
Published: December 2019

Nessa palestra, eu gostaria de traçar uma linha que vai do meu trabalho inicial com a televisão até o meu trabalho atual sobre dados e dataficação que expõe o que mudou e o que não mudou em relação a essa questão fundamental da ordem social. Por dataficação, quero dizer a pressão sentida em todos os lugares atualmente, incluindo as companhias de televisão, para converter todos os aspectos da vida em dados dos quais valores, em especial valores econômicos, podem ser extraídos. Ao fazê-lo, vou falar muito sobre o meu trabalho. Espero que não pareça algo egoísta. O meu objetivo é exatamente o contrário: ao refletir sobre as mudanças e continuidades do meu próprio pensamento, quero trazer dimensões ocultas de mudança social que me fizeram ver claramente, dimensões essas que são muito importantes na compreensão da ordem social em sociedades dataficadas.
Tendencias de la propiedad industrial en el patrimonio intangible empresarial. valoraciones en el entorno cubano
Authors: Contreras Villavicencio Dulce María , Suárez Gutiérrez Evelio , Morán Martínez Liudmila , Correa Álvarez Pascual
Published: December 2019

El presente trabajo aborda la propiedad industrial en el patrimonio intangible de la empresa estatal cubana al identificarse la ausencia de valoraciones sobre la tendencia de esta materia en el país, dificultándose conocer cómo puede armonizarse o adecuarse en el sector empresarial y aprovechar así los potenciales beneficios económicos y sociales que generan sus derechos. Describe prácticas de uso y manejo de propiedad industrial en entidades estatales sobre la base de indagaciones empíricas que evidenciaron el desconocimiento y escaso accionar estratégico, jurídico y contable-financiero de esta rama de la propiedad intelectual, a pesar de reconocerse en la nación la importancia de los bienes inmateriales para lograr éxito económico y desarrollo por ser resultados de la innovación organizacional.
El impacto de las patentes en el sector de las tecnologías limpias: Una mirada desde el análisis económico del derecho
Authors: Quintá Goy Carolina
Published: December 2019

Este estudio tiene por objeto evaluar, desde los preceptos teóricos del Análisis Económico del Derecho, la conveniencia –en términos de eficiencia o ineficiencia–de eliminar el régimen de patentes para la protección de invenciones relacionadas con la mitigación y adaptación al cambio climático. Este trabajo utiliza el enfoque de costos de transacción para analizar la conveniencia de dicha solución.
Cannabis medicinal, más que una encrucijada legal para el tratamiento de la epilepsia
Authors: C. Riveros Diana , González-Valenzuela Laura E.
Published: December 2019

En el presente artículo profundizaremos en los principales hallazgos que evidencian el potencial de diferentes compuestos cannabinoides como fármacos antiepilépticos y el estado actual de la legislación vigente en cuanto a lo concerniente a la utilización y cultivo de la planta de cannabis en Colombia, con miras a vislumbrar los retos que enfrenta la investigación y producción de fármacos antiepilépticos derivados de cannabis en nuestro país. Adicionalmente abordaremos temas como los retos que actualmente tiene la legalización de este tipo de fármacos derivados de cannabis en nuestro país. Ciertamente creemos que el avance en este campo no solo es cuestión del marco jurídico vigente sino también de su oportuna divulgación y el trabajo mancomunado del desarrollo industrial y entidades gubernamentales para el establecimiento claro de la normativa requerida para desarrollar y comercializar medicamentos derivados de cannabis en Colombia.
DANIŞTAY KARARLARI IŞIĞINDA KENTSEL DÖNÜŞÜMÜN HUKUKİ BOYUTU
Authors: AGHABALAEI FANID Nematollah , KAVACIK Dilek
Published: December 2019

Ekonomik, çevresel, kültürel ve göç faktörlerinden dolayı ortaya çıkan olumsuzlukların giderilmesinde kentsel dönüşüm projeleri karşımıza çıkmaktadır. Kentsel dönüşümün sistematik şekilde işlevini yerine getirebilmesi amacıyla sağlam hukuki temellere dayanması gerekmektedir. Kentsel dönüşüm projeleri, Türk hukukunda tek bir hukuki kaynağa dayanmamaktadır. Çalışmamızda, kentsel dönüşümle ilgili hukuki mevzuatı inceledikten sonra bu konudaki uyuşmazlıkları idari yargının temyiz mercii olarak Danıştay kararları çerçevesinde değerlendirilmiştir.

Araştırmanın amacı; idari yargı kapsamında kentsel dönüşümle ilgili dava konularını çeşitli açılardan karşılaştırarak konuyla ilgili yargısal sorunları açıklığa kavuşturmaktır. Uygulama kapsamında, kentsel dönüşüm ile ilgili dava örnekleri Lexpera adlı internet kaynağından elde edilmiştir. Elde edilen veriler sonucunda Danıştay mahkemesinde yer alan kentsel dönüşüm davalarının toplam sayısının 1023 olduğu tespit edilmiştir. Davaların açıldığı şehirlere bakıldığında toplamda 33 şehir karşımıza çıkmaktadır. Şehirler kapsamında en fazla davanın açıldığı şehir olarak Ankara karşımıza çıkmaktadır.

Çalışma kapsamında incelenen davalar sonucunda kentsel dönüşüm süreci ile ilgili sorunlar tespit edilmiştir. Bu sorunlar; yetki problemi, kentsel dönüşümün dayanağı olarak kabul edilen kanunlarla ilgili sorunlar ve süre problemidir. Bu problemlerin çözümü için var olan kanunların revizyonunun gerçekleştirilmesi ve davaların sonuçlandırılma sürelerini uzatacak olumsuzlukların ortadan kaldırılması gerekmektedir.
NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ ÖRNEĞİNDE ÖĞRENCİLERİN ÜNİVERSİTE TERCİH NEDENLERİNİN TESPİTİNE YÖNELİK BİR ARAŞTIRMA
Authors: TÜRKMEN Hasan Hüseyin , DOĞAN Selen
Published: December 2019

Günümüzde hızlı gelişme ve değişmeler nedeni ile her şeyde olduğu gibi adayların üniversite,
fakülte, bölüm ya da program tercihlerinde de çeşitlilikler oluşmuştur. Bu çalışmada, öğrencilerin
üniversite seçiminde etkili olan faktörlerin neler olduğunu belirlemeye çalışmıştır. Adayların
üniversite tercihlerinde; üniversite, fakülte, bölüm, program, tanıtım, aile, puan veya
üniversitenin bulunduğu şehir gibi birçok faktör etkili olabilmektedir. Özellikle yeni kurulan
üniversiteler, yerleşmiş ve büyük üniversitelere göre birçok konuda daha dezavantajlı
olabilmektedir. Çalışma kapsamında, adayların üniversite tercihinde etkili olan faktörleri
ölçmeye yönelik 62 değişkenli bir ölçek oluşturulmuş ve 2016-2017 Eğitim-Öğretim Yılında
Niğde Ömer Halisdemir Üniversitesinde okuyan 1. sınıf öğrencilerinin tamamına anket
uygulanmıştır. Anket sonuçlarına göre öğrencilerin üniversite tercihlerinde en önemli faktörlerin
üniversitedeki eğitim-öğretim kalitesi ve mezunların iş bulma imkânları olduğu ortaya çıkmıştır.
Tercihte en az etkili faktörün ise ailesinin bulunduğu kentte olması olduğu ortaya çıkmıştır.
Öğrenciler için ilin ekonomik şartlarının uygunluğu ve üniversitenin konumu da oldukça etkili
bir faktör olarak belirtilmiştir.