bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical case: switching from basic therapy with methotrexate to therapy with netakimab, an IL-17 inhibitor, in a patient with severe psoriasis
Authors: Svechnikova E. V. , Zhufina S. E. , Morzhanaeva M. A.
Published: March 2023

Currently, psoriasis occupies a leading position in the structure of chronic recurrent dermatological diseases. The modern view on the etiopathogenesis of psoriasis allows us to consider this disease as a systemic, genetically determined, immune-mediated process, which manifests itself not only in the form of damage to the skin, but also leads to the development of various comorbid conditions (lesion of the musculoskeletal system, cardiovascular system, excretory system , metabolic disorders, etc.). This fact radically changes the approach to the treatment of patients with psoriasis, to the selection of a systemic drug. The main points in the management of patients with psoriasis, especially of moderate and severe course: interdisciplinary examination of the patient, prevention of the development of comorbid conditions and irreversible (sometimes disabling) changes in internal organs and systems, timely administration of systemic therapy. The article presents modern aspects of the etiopathogenesis of psoriatic disease, the advantages of genetically engineered biological therapy, and a clinical case of treating a patient with severe psoriasis. A 48-old-patient E. who had been suffering from extensive psoriasis vulgaris for 16 years, which manifested after pregnancy and childbirth, was proscribed the systemic therapy. In July 2022, the patient reported oedema that developed in the lower extremities and face while taking methotrexate, and was examined by a nephrologist. Microalbuminuria nephropathy was diagnosed, which served as a reason for adjusting the systemic therapy for psoriasis. The patient had to be switched to the genetically engineered biological therapy. After 3 subcutaneous injections of netakimab at a dose of 120 mg/week, psoriasis went into a steady-state showing the trend towards a regressing stage. The psoriasis severity index scores decreased by the end of the initiating course of therapy.
Adult female acne: relevance and possible solutions
Authors: Zhukova O. V. , Kasikhina E. I. , Ostretsova M. N. , Ismatullaeva S. S.
Published: March 2023

In recent years, there has been an increase in the proportion of AFA in the structure of acne incidence. The etiopathogenesis of the disease is multicomponent and has not been fully elucidated. It is assumed that hormonal factors and chronic activation of innate immunity are involved in the process against the background of genetic predisposition, which are stimulated by external environmental factors: daily stress, Western-style diet, tobacco use, hormonal drugs, cosmetics. The article presents a modern classification of the clinical course of AFA and scales for assessing the severity of the course of the disease: GEA (Global Acne Severity Scale) and AFAST (Adult Female Acne Scoring Tool). AFA is predominantly characterized by a mild or moderate course. Treatment requires a personalized approach with particular attention to the individual needs and characteristics of adult women. When choosing a topical therapy, the doctor should consider the less pronounced oiliness of the skin, the slow progression of the disease with the outcome in hyperpigmentation and scarring. Modern acne treatment regimens include systemic and topical therapy along with proper basic skin care. The most effective topical agents include retinoids, which can induce a specific biological response by binding and activating retinoic acid receptors. Comedonal and mild papulopustular acne are indications for adapalene monotherapy for acne in adult women. Adaklin (0.1% adapalene) cream is a highly effective first choice for the pathogenetic treatment of AFA. Rational mono- and combination therapy with adapalene is the key to successful external therapy of mild and moderate AFA and prevention of post-acne. The review provided up-to-date, evidence-based information on the clinical presentation, etiopathogenesis, and treatment of adult female acne (AFA).
Aleluia, Mateus Aleluia. Um recorte sobre a sua obra
Authors: Alves Yatan
Published: March 2023

Seu Mateus -as he is respectfully called by many in Brazil -is one of the nicknames ofMateus Aleluia, a Bahian artist, singer, songwriter and musician of great importance in the current African[...] origins, started alongside his companions in the musical trio Os Tincoãs, between the 1960s and 1970s, and continued in a solo career from the 2010s to the present. This article, based on a qualitative methodology, seeks to focus on traces of the life and work of Mateus Aleluia, in order to allow theidentification of the hybridism present in the processes of identity related to the musicality created by this Brazilian artist and the importance of his work for understanding the diasporic cultural reconstruction in which this artist is inserted
The Effect of Chitosan Addition on Characteristics of Biodegradable Plastic from Waste of Nata de Coco using Inversion Phase
Authors:   Jurusan Teknik Kimia, Fakultas Teknik, Universitas Muhammadiyah Surakarta, Hayati Kholisoh , Setyaningrum Claudia Candra , Fatimah Siti ,   Jurusan Teknik Kimia, Fakultas Teknik, Universitas Muhammadiyah Surakarta
Published: March 2023

Exploration of biodegradable plastic material will solve pollution problem. The side product of nata de coco is potential to be proceed as biodegradable plastic due to its cellulose content, up to 42.57%. This research meant to learned the effect of chitosan addition for the making of biodegradable plastic from waste of nata de coco. The inversion phase was used in this study to produce bioplastics then several physical tests, FTIR, and biodegradability examination conducted to evaluate its mechanical properties. This study used complete randomized design combined with factorial design. The bioplastic product was manufactured using cellulose of nata de coco in three variation, 2.00; 2.50; 3.00 gram combined with 3 variation of chitosan, 2.50; 3.00; 3.50 gram. Statistical analysis of all quantitative data was conducted by using Multiple analysis of variance (MANOVA) (p<0.05) using the SPSS-25 program. Based on the result of the research, the value of mechanical properties there is an optimal tensile strength of bioplastics was 4,22 Mpa and elongation was 3,28%. An optimal water resistance value of bioplastics was 70,93%. FTIR result indicate that synthesized bioplastics have a wavelength value similar to the constituent raw material and biodegradability result obtained 80 - 100 %.
Propuesta de mejora tecnológica a un tanque de 5 L de fundición de queso mozzarella por medio de la adaptación de un sistema de control de temperatura
Authors: Garcia Jaimes Luis Eduardo , Restrepo Jiménez Juan Pablo , Jiménez Ocampo Julián
Published: March 2023

En este artículo se presenta una propuesta de mejora para el control de la temperatura de un baño María utilizado para fundir queso mozzarella, con el fin obtener la textura adecuada del queso, evitar que este se queme y reducir pérdidas económicas en locales de comida rápidas. Inicialmente, se realizó el estudio del proceso utilizado en la fundición del queso para determinar los componentes susceptibles de cambio necesarios para mejorar el desempeño del sistema; a continuación, se realizó el modelamiento fenomenológico del proceso lo que sirvió como base para sintonizar adecuadamente los controladores. La propuesta se realiza basada en tecnología y componentes de bajo costo, se presentan los planos eléctricos, planos de instrumentación y de control y se propone el uso de controladores digitales tipo pi para el control de la temperatura. Los controladores se sintonizaron utilizando técnicas de control por modelo interno (imc) y el método del lugar geométrico de las raíces (lgr). Los ensayos realizados en el prototipo muestran mejoras significativas en la calidad de la textura del queso y en el tiempo necesario para su adecuada fundición sin pérdidas de materia prima.
Identificación de parámetros y carga útil de un manipulador robótico 2-DOF: un enfoque de identificación algebraica
Authors: Páez-García Julián Y. , Vargas-Tenjo Laura C. , Charry-Belén Ricardo A. , Coral-Enriquez Horacio
Published: March 2023

Este artículo aborda el problema de identificar los parámetros y las cargas útiles de un manipulador robótico 2-DOF. La metodología propuesta para nuestra investigación fue el método de identificación algebraica realizada en dos etapas: primero, identificando los parámetros del manipulador, y segundo, identificando la carga útil de la punta. Se utilizaron dos casos de simulación numérica diferentes para validar la metodología de identificación propuesta. En ambos casos se logró una rápida convergencia con un bajo porcentaje de error.
A Reflexive Autoethnographic Fragment: Epiphany in a Milkfloat
Authors: Turner David
Published: March 2023

In 'A Reflexive Autoethnographic Fragment: Epiphany in a Milk Float', David Turner uses autoethnographic writing to begin to reflexively consider how his life history might have led him to an interest in a particular topic of study that he was about to embark on as part of research on the development of expertise in sports coaching, associated with a Professional Doctorate in Education course.
Efecto de diferentes tipos de sales en el desarrollo de brinzales de Pinus greggii var. australis
Authors: Ortiz Torres César , Gómez Guerrero Armando , Ortega Escobar Héctor Manuel , López Upton Javier , Plascencia Escalante Francisca Ofelia , Martínez Trinidad Tomás
Published: March 2023

Se estudió el efecto de sales en el desarrollo de brinzales de Pinus greggii var. australis durante 172 días. Se probaron las sales: clorhídrica, sulfática y sulfático-sódica, incluyendo un tratamiento testigo de agua destilada. De estas, se generaron conductividades eléctricas de 3 dS m-1, 6 dS m-1, 9 dS m-1 y 12 dS m-1. Se analizó la evolución del incremento en diámetro y altura de los brinzales. Al final del experimento se compararon los tratamientos con respecto al incremento total en diámetro y altura, biomasa radical e índice de calidad de Dickson, y se observaron cortes transversales de raíces de primer orden por microscopía electrónica de barrido (MEB). Se encontró que los tratamientos con niveles de salinidad de 3 dS m-1, para todos los tipos de sales, fueron los que menos afectaron el desarrollo de los brinzales, mientras que la sal clorhídrica con 12 dS m-1 fue la que más afecto el desarrollo de los brinzales. Por otro lado, las imágenes por MEB mostraron que en la sección de la corteza en la raíz no hubo presencia de gránulos de almidón cuando se trataron con niveles de salinidad de 12 dS m-1, mientras que en el tratamiento testigo sí. Estos resultados sugieren que P. gerggii var. australis tolera niveles de salinidad menores a 3 dS m-1 y su crecimiento se afecta cuando los niveles de salinidad aumentan, generando plantas con parámetros morfológicos no deseados.
Optimizing Lymphedema Outcomes through Lifestyle
Authors: Keith Leslyn , Erkstam Robert
Published: March 2023

Lymphedema, a chronic incurable condition characterized by edema, inflammation, reactive fibrosis, adipose proliferation, and compromised immune function, affects over 250 million people worldwide [1]. Further, a comorbidity of obesity increases the risk of developing lymphedema and can result in irreversible damage to lymphatic function. Access to appropriate and timely lymphedema treatment, performance of proper self-management strategies, and implementation of healthy lifestyle practices are critical for optimal outcomes for those affected. It is vitally important that a healthy lifestyle program for patients diagnosed with lymphedema include strategies for addressing both lymphedema and weight management. In this paper, we describe the essential elements of a successful program for lymphedema and weight management: ketogenic nutrition, exercise, stress resilience, and sleep.
The relationship between online social interaction and self-management in China's large-scale blood glucose self-management population——A mediation model based on self-determination theory (Preprint)
Authors: Chen Xingyu , Wang Ying , Chen Tingting , Fan Guanhua
Published: March 2023

BACKGROUND

Online health communities are increasingly useful in diabetes management.

OBJECTIVE

Thus, this study investigated how the characteristics of interaction and interpersonal support in diabetes online communities are related to self-efficacy and disease self-management.

METHODS

Data on the following variables were collected through online interviews with participants with diabetes or prediabetes who were recruited through snowball and convenience sampling: (1) demographic and clinical factors, specifically gender, age, place of birth, education level, residence, marital status, disease course, and blood sugar level; (2) motivation to participate in an online community; (3) online interaction characteristics; and (4) information dissemination. Multiple linear regression was used to analyze the effects of independent variables on disease self-management, and mediation analysis was used to determine the path of the influence of these variables on self-management.

RESULTS

Self-management was significantly correlated with information intensity (B: 0.159, P < 0.05), motivation to participate in an online community (B: 6.176, P < 0.05), interaction characteristics (B: 0.254, P < 0.05), and interaction intensity (B: 0.142, P < 0.05). Motivation to participate in an online community (36.448%) and information intensity (22.064%) mediated the relationship between interaction characteristics and self-management; the relationship between interaction intensity and self-management was direct.

CONCLUSIONS

We should encourage patients with diabetes to interact and reveive or output social support in diabetes online communities, particularly by sharing information; this increases their trust in and dependence on the group, which improve their motivation for self-management.
MODELS OF RAT SKIN WOUND HEALING: AN OVERVIEW
Authors: PANDEY RATNANJALI , KUMAR GUPTA RAMESH
Published: March 2023

Wounds have developed into one of the earliest types of human pain, with two histories that go back to before the existence of humans. The growth of medical research led to an abundance of new ideas and opened the doors for creating a separate field solely dedicated to treating wounds. The underlying cause, the site of the injury, the mechanism of injury-producing symptoms, the depth and tissue loss of the wound, or the clinical presentation can all be used to categorize wounds. According to studies utilizing animal models, there are four stages of acute wound healing. It is a given that chronic wounds must go through similar underlying mechanisms. Hemostasis, inflammation, proliferation or granulation, and remodeling or maturation are adequate stages of wound healing. There has been a substantial change in how we understand and apply information. This study investigated every aspect of wound healing, including every pathway and model for wound healing.
CLINICAL BIOCHEMICAL PROFILE AND OUTCOME OF CHOLERA OUTBREAK IN A RURAL POPULATION OF KASHMIR VALLEY NORTH INDIA: A RETROSPECTIVE OBSERVATIONAL STUDY
Authors: AHAD WANI ABDUL , NAIK MUZAFAR AHMAD , MEHRAJ SHARIK , ALA AMAN , SHAFI AAMIR
Published: March 2023

Objective: The aim of the study was to investigate the outbreak of a cholera epidemic that occurred in one of the rural areas of Kashmir valley.
Methods: Data were gathered from the medical records for this cross-sectional epidemiological investigation. The inquiry started with the development of a case definition. Line listing, sampling of the patient’s water source and feces, prompt referral, and treatment of those who were vomiting and/or had loose stools were all carried out.
Results: About 26 patients that were suspected to have a cholera like illness were line listed, mostly between 20 and 40 years of age with male-to-female ratio being 1.16:1. The case fatality rate was 0%. The source of water supply was river Jhelum in all cases and on sampling the water source it turned out to be unsatisfactory for drinking purposes.
Conclusion: Preventive strategies for reducing cholera epidemics can include immunization, improving water conditions, along with the sanitation and hygiene.
ENHANCEMENT OF DISSOLUTION OF CANDESARTAN CILEXETIL
Authors: C APARNA , M ANUSHA , B MANISHA
Published: March 2023

Objective: The main aim of our investigation was to enhance the dissolution of Candesartan Cilexetil (CC), a prodrug of Candesartan, used in the treatment of hypertension. CC bioavailability is dissolution rate limited. The drug was formulated using various excipients such as surfactants, and liquid lipids to improve solubility, dissolution, and hence bioavailability.
Methods: The solubility of CC was determined at 25°C by shake flask method and those showing maximum solubility were selected for the formulation of CC. In vitro dissolution studies were done in different media in pH 6.8 phosphate buffer with 1% SLS, tween 20, and 0.1 N HCl with 1% SLS. The surface morphology of LBDDS was studied with scanning electron microscope (SEM) and the crystallinity of the drug and the formulation were studied using X-ray diffraction (XRD).
Results: CC showed maximum solubility in transcutol and labrasol, which, hence, were selected as excipients for the formulation of CC capsules. Drug release was high in 0.1 N HCl with 1% SLS and, hence, was selected as the dissolution medium. The dissolution profile for formulation F5 containing the drug with transcutol and labrasol showed the highest drug release among all formulations, that is, 94.09%. The SEM of the F5 formulation showed that the drug was completely embedded into the lipid matrix and particles were spherical and porous with a size of around 25 μ. XRD of formulation F5 indicated the absence of crystallinity in CC capsules containing transcutol and labrasol.
Conclusion: It was concluded that CC containing transcutol and labrasol significantly increases the solubility and dissolution of the drug.
AGE-REALTED MACULAR DEGENERATION AND SERUM LEPTIN: A CASE–CONTROL STUDY
Authors: MAHERDA LAKSHITA , JAIN KALPANA , AGARWAL PULAK , BHARGAWA POONAM
Published: March 2023

Objective: The objective of this study was to evaluate the association of serum leptin levels with presence and severity of age-related macular degeneration (AMD).
Methods: A hospital-based case–control study conducted on 84 patients (42 cases and 42 controls) of either sex complaining of diminution of vision aged 40 years and above between August 2019 and 2021.
Results: Mean serum leptin level in cases was 1.55±0.99 ng/mL and control was 2.11±0.88 ng/mL (p<0.008). The serum leptin level was negatively correlated with early (1.06±0.99 ng/mL), intermediate (0.50±0.08 ng/mL), and dry age-related macular degeneration (ARMD) (0.29±0.12 ng/mL). However, we found higher serum leptin levels in exudative ARMD (2.58±0.99 ng/mL). Maximum number of cases were of exudative AMD (42.86%) followed by early AMD (33.34%) and intermediate and dry AMD (11.91% each).
Conclusion: We found a decrease in serum leptin levels as disease severity increases from the early AMD to intermediate AMD and Dry AMD. However, the levels of serum leptin levels were higher in patients with exudative AMD. This may be due to some pathological process that is different in dry and exudative AMD. This can form the basis for further research in future.
MANAGEMENT OF NECK FEMUR FRACTURE IN ADULT BY MINI-DHS AND BIPLANE DOUBLE SUPPORTED SCREW FIXATION TECHNIQUE
Authors: PACHORI SACHIN , SINGH PRATAP , KUMAR MOHIT , CHOUDHARY LAXMAN
Published: March 2023

Objective: The aim of the study was to study the management of neck femur fracture in adult by mini-DHS and BDSF technique; an innovative procedure.
Methods: This study was conducted on 20 Patients with neck of femur fractures, who underwent mini DHS with 6.5 mm cc screw with biplane double supported screw fixation technique in the Department of Orthopaedics, Government Medical College and Associated Groups of Hospitals, Kota during year 2019–2021.
Results: Out of 20 cases, 14 are male and six are female and age-wise distribution <20 years, one patient 20–40 years, 11 patients and >40 years, eight patients. Mode of injury mainly road traffic accident, Average Harris hip score 91.35, 15 patients (75%) achieved excellent result, radiologically fracture union was seen in 19 patients (95%).
Conclusion: Although anatomical reduction is crucial, Mini DHS with 6.5 mm cc screw with BDSF-method ensures reliable fixation, early rehabilitation, and good functional outcome especially in adult.
PREVALENCE AND PATTERN OF SELF MEDICATION TO PREVENT COVID-19 INFECTION: POPULATION-BASED SURVEY
Authors: GOHIL TORAL , PATEL ALPESH , PATEL ZANKRUT , CHAUDHARY VIPUL , PATEL SUMIT
Published: March 2023

Objective: During COVID-19 pandemic, people have practiced one or more self-medication (SM) for prevention of the disease. This requires monitoring and evaluation to see the pattern of medicine used. Hence, in this study, we evaluated the prevalence and pattern of SM in various group of people.
Methods: A cross-sectional study was conducted as an online survey on individuals who were in contact through mobile phone from October 2020 to March 2021. A pre-structured questionnaire-based Google form that contain questions related to SM practiced was prepared and circulated on social media application and email. Submitted forms were analyzed using Microsoft excel.
Results: Out of 779 forms, 775 (99.4%) filled completely were considered in result. Majority (52%) of participants were in the age group of 20– 40 year. Six hundred and fifty-two (84%) participants had taken medication, out of which 40% were modern medicine users and rest 44% had used other than modern medicine. In modern medicine, Vitamin C was taken by 72% and in other group, lemon water was taken by 99% of participants. The prevalence of SM was highest among urban population (43%) with education up to postgraduation (53%). Health worker (57%) were highest among users. SM advice was received by doctors in 60% participants with belief of effectiveness against COVID-19 infection.
Conclusion: SM was practiced by half of the participants that includes modern as well as other than modern medicine. It was mainly seen among people with higher education and who are associated with health-care system.
PREFERRED PHARMACEUTICAL FORMULATIONS BY PATIENTS SUFFERING FROM SEXUAL DYSFUNCTION VISITING PSYCHIATRY OUT PATIENT DEPARTMENT IN AN TERTIARY CARE CENTER
Authors: Shende Neha , Nerlekar Sharmada , Rashmi Abhilasha , Karia Sagar , Pawar Sudhir
Published: March 2023

Objective: Sexual dysfunctions are increasing day by day. Various formulations are available for the treatment of same. There has been psychological mind-set among Indian patients to have powdered medicines for the sexual dysfunction management. The aim of this study was to analyze the preferred formulation by the patients for the treatment sexual dysfunction.
Methods: A cross-sectional and observational study was undertaken from January 2018–January 2019 in psychiatry OPD of a tertiary care teaching institute after approval from the Institutional Ethics Committee. A semi-structured questionnaire was made collecting information on demographic details and preferred pharmaceutical formulations for the treatment of sexual dysfunctions.
Results: Out of 164 participants who were analyzed, the most common age group having sexual dysfunctions was found to be 21–30 years (44%). Patients preferred Ayurvedic form of treatment (38.41%) over Allopathic (23.17%). Patients were in favor of SOS medications (51.83%) than day or night doses. Majority of the patients wanted drugs in tablet form (67.07%), in monthly doses (43.9%), of white color (39.02%), along with water (54.88%) and at <Rs.100 per strip (67.07%).
Conclusions: Majority of the patients prefer Ayurvedic form of treatment and SOS, on monthly basis, white colored tablets, taken with water at affordable prices. These factors need to be kept in mind while formulating new drugs and guidelines to ensure better compliance.
EFFICACY OF INTRAVENOUS ESMOLOL WITH INTRANASAL NITROGLYCERINE SPRAY GIVEN BEFORE ENDOTRACHEAL EXTUBATION ON THE ATTENUATION OF PRESSOR RESPONSE: A COMPARATIVE STUDY
Authors: Kokate Minal V , Kokate Vikram R , Mahure Shirish M , Jumade Prashil P
Published: March 2023

Aims and Objectives: The aim of the study was to compare the effects of intravenous esmolol and intranasal nitroglycerine spray on attenuation of extubation pressor response in terms of hemodynamic parameters and to compare the adverse effects, if any, of either drug.
Methods: This was a randomized comparative study conducted in a tertiary care medical college in which 64 patients of ASA Grade I with age between 18 and 60 years, including both males and females undergoing elective non cardiac surgeries under general anesthesia with orotracheal intubation were included in this study on the basis of a predefined inclusion and exclusion criteria. Patients were divided into two groups (Depending on whether they received Intravenous Esmolol or NTG spray) of 32 patients each. Attenuation of extubation pressor response in terms of hemodynamic parameters (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP], heart rate, and rate pressure product) were recorded and compared before induction, during surgery and postoperatively up to 10 min after surgery.
Results: The gender distribution was comparable in both the groups. The mean age of patients in Group A and Group B was found to be 36.90±10.12 and 35.20±11.32 years, respectively. The mean age of both the groups was found to be comparable with no statistically significant difference. Both the study groups were comparable in base line parameters with no significant difference seen in mean age, mean heart rate, mean SBP and DBP, MAP, anesthesia time, and surgery time. Both drugs controlled the blood pressure changes effectively; however, NTG group had a better control of systolic as well as DBP. Heart rate was better controlled in esmolol group.
Conclusion: Intranasal nitro-glycerine and intravenous esmolol before tracheal extubation in ASA Grade I patients are simple, effective, and practical methods of blunting cardiovascular responses to tracheal extubation.
ATTENUATION OF LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION-INDUCED SYMPATHOMIMETIC RESPONSES WITH INTRAVENOUS ESMOLOL AND LIGNOCAINE: A COMPARATIVE STUDY
Authors: TRIPATHI SONALI , KHUSHRAM BHUPESH , MERAVI JYOTI , DANDOTIYA DILEEP
Published: March 2023

Introduction: Direct laryngoscopy and endotracheal intubation are a noxious stimulus and induces sympathomimetic responses. Although properly tolerated in normal and healthy subjects, it can impose serious arrhythmias, left ventricular failure, myocardial ischemia, or rupture of cerebral aneurysm in vulnerable patients. Various techniques are currently working to attenuate this response, but, so far, none of them have been proven to be superior. Esmolol and Lignocaine; attenuate those responses however are related to some untoward outcomes such as bradycardia and hypotension. In low doses, the chances of those expected untoward outcomes are relatively low.
Aim and Objectives: We designed this prospective clinical education to assess and compare the efficacy of intravenous Esmolol and Lignocaine in attenuating sympathomimetic responses to laryngoscopy and endotracheal intubation.
Methods: After the Institutional Ethics Committee approval, 52 consenting patients of ASA physical repute I or II of age between 20 and 60 years, scheduled for surgeries requiring general anesthesia, remained randomly owed to two groups; Group E and Group L, given 2 mg/kg of inj. Esmolol intravenously and inj. Lignocaine 2 mg/kg, respectively, 2 min before intubation. Final outcome variables such as heart rate (HR), systolic blood pressure (BP), diastolic BP, and mean arterial pressure (MAP) had been recorded and compared between the two groups immediately after intubation (AI) and then at 1, 3, and 5 min AI.
Results: There was no statistically huge distinction regarding the demographic profiles of both the study groups. There has been a substantial rise in mean HR in the lignocaine group all through laryngoscopy and intubation, which did not settle to baseline level even after 5 min (p<0.0001). In the esmolol group, a significant attenuation of HR was observed immediately AI and 1, 3, and 5 min following intubation. MAP was well controlled in the esmolol group. Throughout the study period, readings of mean arterial pressure were much higher in esmolol group. In the lignocaine group, the values of study parameters were higher than the baseline at every point of time. Diastolic BP was elevated in both groups.
Conclusion: Esmolol was found to be more effective for attenuation of hemodynamic tension response to laryngoscopy and intubation when compared with Lignocaine. However, Lignocaine is also safe and effective to some extent.
Some Contributions of Neuroscience at School, through the Continuing Teacher Training Offered
Authors: Beltrão Monique Ferreira Monteiro , Soares Ângela Mathylde
Published: March 2023

This article seeks to investigate the contributions of neuroscience to the process of teaching and its relationship with the methodologies used in the classroom. this research discusses data obtained in the continuing education offered by the municipality of Vila Velha in Espírito Santo, which analyzes the teaching understanding of topics such as neurodidactics and neurosciences, and how this knowledge can contribute to practice in classroom. It also presents the data collected through training actions. Continued, as well as about the pedagogical practice and the methodologies used by participating teachers, thus analyzing the relationship between neurosciences and practice teacher. We seek to understand how active and pedagogical methodologies can be relate to neuroscientific knowledge and their contributions to the process of teaching and learning, also through bibliographic reviews. Starting from indicative data on the subject of Neuroscience in Education are evident from need for investment in the initial and continuing training of teachers, in order to that the teaching and learning process promoted in a collaborative perspective, in which teachers and students can interact. The research field was composed of regent teachers of the classes of the Municipal Education Network of Vila Velha/ES, UMEF Municipal Unit of Elementary Education Pedro Herkenhoff. The methodology used this study presents a qualitative approach applied by a random sample, consisting of teachers who attend the Municipal Education Network of Vila Velha/ES.
ИСПЫТАТЕЛЬНЫЙ ЦЕНТР АО «ТЕСТПРИБОР»: КАК ГАРАНТИРОВАТЬ НАДЕЖНОСТЬ
Authors: Шеховцова Е.
Published: March 2023

Одно из важных направлений развития АО «ТЕСТПРИБОР» – расширение видов проводимых работ в испытательном центре. В статье представлены возможности компании в части проведения сертификационных, квалификационных, приемо-­сдаточных, периодических и других видов испытаний.
ПРИМЕНЕНИЕ ФОТОЛИТОГРАФИИ ДЛЯ ИЗГОТОВЛЕНИЯ МЕТАЛЛИЧЕСКИХ КОМПЛЕКТУЮЩИХ В АО «ЗПП»
Authors: Панкратова Е. , Шугаепов Ш. , Ермолаев Е. , Егошин В.
Published: March 2023

Рассмотрено применение фотолитографии в АО «Завод полупроводниковых приборов» (АО «ЗПП») для изготовления различных металлических комплектующих. Приведены примеры изделий, изготовленных с использованием данной технологии.
Интегрально-оптические C-NOT гейты: оценка основных парметров для практической реализации
Authors: Петров В.М. , Коротеев Д.А. , Семисалов Д.А. , Страшилин В.С. , Хлусевич Д.С. , Яковлев М.И. , Парфенов М.В.
Published: March 2023

Рассмотрено влияние отклонения параметров светоделителей на работу квантового
фотонного гейта в интегрально-оптическом исполнении. Показано, что требуемая
точность вполне достижима для электро-оптического управления в геометрии
X-делителя. Проведенные оценки длины устройства показывают возможность его
реализации даже на подложках длиной 3 дюйма.
Hechas a mano: mujeres trans* en tres contextos urbanos de Chiapas
Authors: Gómez García Irazú
Published: March 2023

El título del presente libro es una invitación a pensar la diversidad cultural desde el género. En su organización, el sentido de la expresión «hechas a mano» coloca la reflexión en el tipo de relaciones de poder, los límites y las consecuencias que cruzan a las mujeres trans* cuando deciden vivir una identidad genérica distinta a la dictada por la norma binaria, donde se exige una congruencia biológico-cultural (hembra-mujer) para validar a las personas en la interacción social cotidiana. No es casual la alusión al género desde una perspectiva que ubica el poder en las entrañas de la discusión.
Sequía y producción de café:
Authors: Martínez Torres Nelly Azalia , Santacruz de León Germ´án
Published: March 2023

Objetivo: determinar la incidencia de la sequía en los niveles de productividad de café e identificar la percepción de los productores de café en la Huasteca Potosina.
Diseño metodológico: se determinó el índice estandarizado de precipitación para 12 meses con datos de cinco estaciones pluviométricas para el periodo 1961-2018, localizadas en la zona cafetalera de la Huasteca Potosina. Se comparó con el comportamiento temporal de las superficies sembradas, cosechadas y el volumen de producción para el periodo 1985-2020. Se correlacionó la precipitación pluvial anual de las cinco estaciones con la superficie sembrada y la producción mediante la determinación del coeficiente r de Pearson. Se aplicaron 25 entrevistas estructuradas a campesinos productores de café.
Resultados: los periodos ligeramente secos inciden en la superficie cosechada y en el volumen de producción, con valores cercanos a los valores promedio. Los valores de r de Pearson indican muy baja correlación de la precipitación pluvial con los volúmenes de producción, en tanto que 60% de los entrevistados señala que la variabilidad climática provoca efectos en la producción cafetalera.
Limitaciones de la investigación: la determinación del índice estandarizado de precipitación con el que se estiman periodos secos y húmedos solo considera los valores de precipitación pluvial medidos en cada estación meteorológica.
Hallazgos: la comparación del índice estandarizado de precipitación con el comportamiento anual de la superficie cosechada y el volumen de producción de café muestran que la precipitación pluvial es relevante en la producción cafetalera, eso coincide con la percepción de los productores cafetaleros.
astronomía como estrategia interdisciplinaria para fortalecer la gestión académica en la Institución Educativa San Antonio de Prado
Authors: Arenas Hernández Helbert Gustavo , Gómez Arbeláez Dora María
Published: March 2023

Mediante una propuesta de aplicación de unidades didácticas basadas en astronomía, se diseñó un proyecto que buscó fortalecer la gestión académica desde una perspectiva de currículo interdisciplinar y la implementación de Ambientes Virtuales de Aprendizaje − AVA dentro de la Institución Educativa San Antonio de Prado. Lo anterior parte desde el análisis del plan de estudios y encuestas aplicadas a algunos docentes y estudiantes que mostraron que no había interdisciplinariedad o proyectos que vincularan diversas áreas del conocimiento. Posteriormente, se convocó a la participación de docentes de diferentes áreas en la construcción de unidades didácticas basadas en astronomía desde la indagación y el enfoque STEAM. Una vez superada la fase anterior, se evaluó y mejoró el diseño de la propuesta mediante la aplicación de Google Formularios a toda la comunidad educativa que participó del proyecto, el estudio de los registros obtenidos a partir de la observación participante y las encuestas analizadas por medio del programa Atlas.Ti 8.0, lo cual contribuyó a mejorar la gestión académica. Finalmente, se evidenciaron avances en los procesos de interdisciplinariedad, y se mostró que la astronomía y el modelo STEAM permitieron el alcance de las competencias planteadas desde el PEI.
Survey Paper for Virtual Tour of Educational Institute
Authors: Gawas Mr. Rohit , Nimbalkar Mr. Shivam , Vyavahare Mr. Aditya , Magdum Mr. Aryan , Dange Prof. Amol
Published: March 2023

Abstract: The location of the Annasaheb Dange Group of Institute,Ashta is a part of community that can be made into attraction for stakeholders like students, parent and society, for ed- ucational brilliance including scenic views, as well as trees and plants. The educational institute has undertaken various efforts to share the information about academic excellence as cultural and sports excellence through portals and web pages. However, the method of information delivery - display and delivery of static text and pictures which is not that effec- tive to the viewers eyes.
A Meta-Synthesis on the Experiences of Persons with Disabilities towards Disaster Preparedness
Authors: Cana Joey , Cheng Dynzyl , Socorro Sharr Christian del , Espeleta Keziah Yves , Gabilan Nicole Anne , Jr. Angelito Cabanilla
Published: March 2023

Abstract: In times of disaster, it is essential to consider the experiences and preparedness of persons with disabilities. This study provided a meta-synthesis of disaster experiences and preparedness of people with disabilities. Eighteen (18) out of 504 studies were chosen based on the inclusion and exclusion criteria. The quality of the selected articles was assessed using the Critical Appraisal Skills Programme (CASP) and arranged using the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) diagram. The synthesized data were analyzed using Clark and Braun’s six-step thematic analysis, and have resulted in twelve (12) themes, namely: increased vulnerability and marginalization, inaccessible formats of information limit mobility and awareness, initiatives are transparent, dependency on people, post-disaster services are not inclusive, disaster creates injuries and disabilities, participation in planning is limited, unfamiliarity results in limited awareness, initiatives improve preparedness, plans are developed for them rather than by them, preparation is costly, and develops self-made strategy for survival. In conclusion, the preparation and participation of people with disabilities in disaster risk reduction and management are limited. It is recommended that disaster risk reduction training and planning be inclusive for people with disabilities
A Review of Hybrid Floating Solar Plant Designs
Authors: Bhattacharya Debshree
Published: March 2023

Abstract: The demand for power will have doubled by the year 2050. Solar energy currently meets a small percentage of the world's demand, despite its enormous potential as an eco-friendly method for producing electricity. Utilizing land resources sustainably is one of the challenges. As an alternative, floating PV (FPV) plants on bodies of water, such as a dam, reservoir, canal, etc., are gaining popularity worldwide. This project aims to design a hybrid floating solar system that can produce renewable energy in light of the above. Among the hybrid technologies addressed are FPV & hydro systems, FPV & pumped hydro, FPV & wave energy converter, FPV & solar tree, FPV & tracking, FPV & conventional power, and FPV & hydrogen. The review also summarises the main benefits and drawbacks of hybrid floating solar PV (FPV) systems. The hybrid FPV technologies with hydro and solar energy input were some of the most promising ones for producing power efficiently. The important ideas in this paper advance understanding and could serve as a catalyst for the creation of environmentally friendly, sustainable hybrid floating installations
Autoconcepto, ajuste escolar y cansancio emocional en estudiantes que realizan estudios de bachillerato en línea
Authors: Reynoso González Oscar Ulises , Ibarra Aguirre Enrique , Portillo Peñuelas Samuel Alejandro
Published: March 2023

El objetivo del trabajo es describir el comportamiento del autoconcepto, ajuste escolar y cansancio escolar en una muestra de estudiantes que realizan estudios de bachillerato en línea en México; identificar diferencias en función del sexo, analizar sus relaciones y generar un modelo predictivo. Es un trabajo cuantitativo, de tipo observacional y diseño transversal predictivo. Participan 578 estudiantes de los 32 estados de la república mexicana. Se utilizó un cuestionario sociodemográfico, la escala de Autoconcepto AF5, la Escala Breve de Ajuste Escolar y la de Cansancio Emocional. Los hallazgos muestran que el autoconcepto emocional, social y físico presentan los más bajos puntajes. Los hombres logran puntuaciones más altas que las mujeres en todas las dimensiones del autoconcepto, mayormente en la emocional. El total de los participantes mostraron niveles adecuados de ajuste escolar, tanto en el total como en todos sus factores. En el cansancio emocional, las mujeres manifestaron niveles ligeramente superiores que los hombres. La asociación entre el autoconcepto y el ajuste escolar fue de tipo positiva; mientras que la relación de ambas con el cansancio emocional fue de tipo negativa. Se sugiere profundizar en las variables de estudio e incorporar en el análisis el factor evolutivo del autoconcepto, más allá del contexto educativo.
Зэсийн хүдрийн рентгенографын тоон анализ
Authors: Д Сангаа , С Даваа , П Зузаан , Б Отгоолой , Л Дэлгэрбат , Г Жаргалжав , Л Ням-Очир , Д Отгонбаяр
Published: March 2023

Эрдэнэтийн зэсийн хүдэрт тоон анализ хийж халькопиритийн (CuFeS2) агуулгыг тодорхойлж, богино хугацаанд хүдэр дэх CuI-ийн хэмжээг үнэлэх аргачлал боловсруулав.
Хүнсний бүтээгдэхүүнд нэмж байгаа химийн зарим элементүүдийг тодорхойлох цөмийн физикийн аргууд
Authors: Ш Гэрбиш , Ж Баярмаа , Н Балжинням , Д Баатархүү , Б Далхсүрэн , О Отгонсүрэн
Published: March 2023

Алттай архины дээжинд хяналтын шинжилгээний зорилгоор алтны хэмжээг МУИС-ийн ЦСТ-ийн электроны цикл хурдасгуур микротрон МТ-22 ашиглан гамма идэвхжилийн аргаар тодорхойлох боломжийг туршсан судалгааны дүнг энэ ажлаар үзүүлэв.
Хатуу биеийн дулаан багтаамжийн классик ба квант онол
Authors: Г. Шилагарди  , Ж. Ванчинхүү  , Л. Дэмбэрэл  , Р. Галбадрах  , Л. Энхтөр  , С. Мөнхцэцэг
Published: March 2023

Аннотация: В работе было изложено основное положение классическое и квантовое теорий теплоемкости твёрдых тел, а также квази квантовой теории Дебая и Эйнштейна
Эйнштейний онол ба дорнын гүн ухаан
Authors: О. Лхагва  , Ц. Сайнсанаа  , Л. Эрдэнэтуяа
Published: March 2023

Эйнштейний онол ба дорнын гүн ухаан
Эйшнтейний сүүлчийн мөрөөдөл
Authors: Н. Түгжсүрэн
Published: March 2023

Эйшнтейний сүүлчийн мөрөөдөл
Нэрт эрдэмтэн, сурган хүмүүжүүлэгч проф Д.Батсуурийн Монголын боловсрол, шинжлэх ухаанд оруулсан хувь нэмэр
Authors: Б. Бурмаа
Published: March 2023

Нэрт эрдэмтэн, сурган хүмүүжүүлэгч проф Д.Батсуурийн Монголын боловсрол, шинжлэх ухаанд оруулсан хувь нэмэр
Академич , профессор Д. Батсуурь - Хэлэнгийн геологийн экспедиц
Authors: С. Дашдаваа  , Д. Чулуун  , П. Дугараа
Published: March 2023

Академич , профессор Д. Батсуурь - Хэлэнгийн геологийн экспедиц
Альбумин, Эозиний Уусмалын Сонофотолюминесценц
Authors: Р. Хоролжав  , Д. Нямаа  , Д. Найдан  , С. Эрхэмбаатар
Published: March 2023

Альбумин, Эозниний усан уусмалыг 22,5 кГц давтамжтай хэт авианы пьезокерамик үүсгүүрээр үүлчилж. 546 нм долгионы урттай үзэгдэх гэрлийн мужид уусмалын сонофотолюминесцентийг бүртгэв. Сонофотолюминесцийн энергийн шилжилтээр үүсэх сонофотолюминесц нь бага эрчимтэй учраас флуоресценцийг мэдрэмжүүлэгч (сенсибилизатор)-ээр будагч бодис эозинийг авч хэрэглэв.
Дулаалгын тунгалаг системүүд
Authors: С. Баяннасан
Published: March 2023

Abstract: In a southerly oriented facade, a Transparent Thermal Insulation (TI) converts incoming solar radiation into usable heat which can be transported to the interior of the building. Transparent insulations are generally installed in front of massive building walls wich serve as energy storage. Different variations of installations have been simulated with a computer program. Real weather data from the Test Reference Year for Ulaanbaatar, Mongolia have been taken into account, a heat gain of as high as 175,8 kWh/m2 seems attainable in wintertime.
Computer simulation on photoconductivity in hydrogenated amorphous silicon thin films
Authors: SH. Chadraabal
Published: March 2023

Abstract: We used a computer simulation for photoconductivity as a function of temperature in a-Si:H thin films. Utilizing a two level model for photoconductivity, calculated stationary photoconductivity values in a wide range of temperature. The nonlinear differential equations system (1) was solved numerically by iteration technique. For the mobility edge of a-Si:H films, we assumed a model with two level dangling bond centers in the mobility gap. It was shown that the computer modeling results describe well influences of such parameters, as exciting light intensities, capture coefficients for electrons and holes and state densities of dangling bond center levels on behavior of temperature dependence curves of photoconductivity in a-Si:H films.
Огторгуй хугацаа нар шиг гэрэлтэн цацарч энерги ялгаруулах нь
Authors: Х. Намсрай
Published: March 2023

Огторгуй хугацаа нар шиг гэрэлтэн цацарч энерги ялгаруулах нь
Life time and mobility product of injected charge carriers in copper II phthalocyanine thin films with different phase structure
Authors: Lkhamsuren Enkhtur , Ragchaa Galbadrakh , Шилагарди Г.
Published: March 2023

Using near-field scanning microwave microprobe (NSMM) method we have observed thedistribution of injected charge carriers along conductivity channel in CuPc thin film on dependence ofapplied bias. From scan data were calculated diffusion length and product fi-r for injected charges fromAu electrode to CuPc thin film. By scanning electron microscopy method were investigated morphologyproperties of CuPc thin films, which explains the difference of product /n-r for injected charge carriers inCuPc thin films with different crystal phase structure.
Өөрөө цуглуулагч кер орчин дахь гэрлийн стационар соронзон долгионы бодлогын шийд тусгай функцээр илэрхийлэгдэх тусгай тохиол
Authors: Нямсүрэн О. , Очирбат Г.
Published: March 2023

Өөрөө цуглуулагч кер орчин дахь гэрлийн стационар соронзон долгионы бодлогын шийд тусгай функцээр илэрхийлэгдэх тусгай тохиол
Дулааны 4 дүгээр Цахилгаан станцын үнсэн сангийн цацрагийн түвшин
Authors: М. Алтангэрэл  , M Н. Норов , Энхбат Н. , Цэрэнбалжид Ц.
Published: March 2023

Энэхүү ажлаар дулааны 4-р цахилгаан станцын үнсэн сангийн дээжүүдэд гамма-спектрометрийн үнэмлэхүй арга ашиглан байгалийн цацраг идэвхт 226Ra, 232Th, 40K зэрэг изотопуудын хувийн идэвхийг тодорхойлж уг дүнгээ ашиглан радийн эквивалент идэвх, гамма цацрагийн агаар дахь шингэсэн тунгийн чадал, радоны эминацийн коэффициент зэргийг тооцолж үнсэн сангийн цацрагийн дэвсгэр түвшинг тогтоов.
Монголд Судалгааны реактор байрлуулах газрыг сонгох асуудалд
Authors: Одмаа С. , Норов Н.
Published: March 2023

Судалгааны реактор болон цөмийн байгууламжийг байрлуулах газрыг сонгоход баримтлах зарчим, шалгуур, үнэлгээний асуудлыг авч үзэв. Түүнчлэн судалгааны реактор байрлуулахаар сонгосон газраас реакторт болон реактораас уг газарт нөлөөлж болох хүчин зүйлсийг нарийвчлан судалж, холбогдох түүхэн өгөгдлийг цуглуулж үндэслэл боловсруулах, ийм хоёр талын нөлөө аль болох багатай газар сонгох хэрэгтэйг харуулсан болно.
Определение Содержания Азота В Пшенице По Захвату Тепловых Нейтронов
Authors: Отгоолой Б. , П. Зузаан
Published: March 2023

Получены оценки длины диффузии тепловых нейтронов и миграции нейтронов в пшенице длянейтронов от Ри-Ве источника. Разработан метод и создана опытная установка для определениясодержания азота в органических вещества.
Особенности радиоспектроскопии каменных углей низкой степени метаморфизма
Authors: Адашкевич С.В. , Баев В.Г. , Лапчук Н.М. , Стельмах В.Ф. , Шилагарди Г. , Sambuu Munkhtsetseg , Ragchaa Galbadrakh , Цоохүү Х. , Lkhamsuren Enkhtur
Published: March 2023

Особенности радиоспектроскопии каменных углей низкойстепени метаморфизма
Основные Концептуальные Принципы Проектирования Сенсоров Слабых Магнитных Полей на Эффекте Холла
Authors: M В.А. Ярмолович , Шилагарди Г. , Прокошин В.И. , Драпезо А.П. , Цоохүү Х. , Д. Төмөрбаатар  , Түвшинтөр П.
Published: March 2023

Основные Концептуальные Принципы Проектирования СенсоровСлабых Магнитных Полей на Эффекте Холла