bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Keefektifan Kerjasama dengan Influencer dalam Komunikasi Pemasaran Berdasarkan Perspektif Electronic Word of Mouth (EWOM)
Authors: Widodo Andeka , Lala Amelia Rizki , Indah Lestari Rani , Hidayati Nurul , Nur Apriana Indah , Alamsyah Idris Fahmi , Yogia Isnaini Vitria
Published: December 2024

Influencer marketing telah menjadi salah satu metode pemasaran digital yang berkembang pesat dalam beberapa tahun terakhir. Sebagai bagian dari transformasi pemasaran tradisional ke digital, konsep ini memanfaatkan pengaruh individu yang memiliki audiens setia di berbagai platform media sosial. Dalam hal ini, Electronic Word of Mouth (EWOM) berperan sebagai katalis utama, karena pengaruh komunikasi personal yang dilakukan secara digital lebih dipercaya dibandingkan iklan konvensional. Saat ini, electronic word of mouth (EWOM) menjadi elemen penting dalam pemasaran karena komunikasi dalam bentuk EWOM dapat memengaruhi keputusan pembelian konsumen. Di era digital seperti sekarang, EWOM tidak lagi memerlukan interaksi tatap muka secara langsung. Definisi EWOM pun kini lebih luas, mencakup tidak hanya percakapan langsung tetapi juga interaksi yang terjadi di dunia maya.  Hasil penelitian mengindikasikan bahwa kerjasama dengan influencer yang memiliki audiens yang relevan dan terpercaya dapat meningkatkan visibilitas merek dan interaksi dengan konsumen secara signifikan. Namun, keberhasilan strategi ini sangat bergantung pada pemilihan influencer yang tepat dan kesesuaian pesan yang disampaikan dengan nilai-nilai merek. Temuan ini memberikan wawasan berharga bagi influncer pemasaran tentang cara  penggunaan pemasaran melalui media sosial  untuk mencapai tujuan komunikasi pemasaran mereka.
Position of Credit Agreement in the Provision of Credit Facilities at a Banking Institution
Authors: Sampurna Asbit Iman
Published: December 2024

This study aims to determine the position of the credit agreement in the implementation of the provision of credit facilities at a banking institution, in addition to determining the legal consequences that will occur if the requirements of the credit agreement are not met. The method used in this study uses the normative legal approach method, namely an approach based on the main legal material by examining theories, concepts, legal principles and laws and regulations related to this study. This approach is also known as the literature approach method. The results of this study indicate that, first: the position of the credit agreement in the credit granting process is very important. Second: in order to provide legal protection for the parties, both creditors and debtors, the credit agreement must be implemented in accordance with applicable requirements.
Legal Protection for Winners of Land Rights Auctions That Are the Object of Dispute in Court Cases
Authors: Adhitya Bakhtiar Satria , Hafidz Jawade
Published: December 2024

This study aims to analyze: 1) Legal implications for the implementation of land rights auctions that are still the object of dispute in cases in court. 2) Legal protection for winners of land rights auctions that are the object of dispute in cases in court. The approach method used in this study is a qualitative approach. This type of research is empirical research. The types and sources of data in this study are primary data obtained through interviews and secondary data obtained from literature studies. The analysis in this study is prescriptive. The results of the study concluded: 1) Legal implications for the implementation of land rights auctions that are still the object of dispute in cases in court can include several complex aspects, namely legal uncertainty of land rights, difficulty in obtaining absolute ownership, potential financial losses, obligations to resolve potential further disputes, and the influence of court decisions. Court decisions related to auction results will greatly affect the legal certainty of auction winners, because the filing of lawsuits by other parties after the auction affects the validity of the ownership rights obtained. If the court provides clear certainty regarding land ownership to the auction winner, this will strengthen its legal certainty. However, if there is still uncertainty or disputes regarding ownership, legal certainty can continue to be questioned. 2) Legal protection for the winner of the auction of land rights that are the object of dispute in a case in court, namely: If another party files a lawsuit against the auction object, then the court decides that the auction is legally valid, then in this case the auction winner's rights to the auction object already have permanent legal force and can no longer be challenged by any party. If there is a lawsuit and then the court decides that the auction is void because there is an element of an unlawful act, then the legal protection obtained by the auction winner is to be able to claim back the purchase money for the auction object that has been paid.
Notary's Responsibility for Making Inheritance Certificates That Do Not Involve All Heirs
Authors: Susilowati Ita Niya
Published: December 2024

This study aims to analyze: 1) The notary's responsibility for making a certificate of inheritance that does not involve all heirs. 2) Legal protection for the parties for making a certificate of inheritance that does not involve all heirs. The approach method used in this study is the empirical legal approach method. This type of research is analytical descriptive research. The types and sources of data in this study are primary data and secondary data obtained through interviews and literature studies. The analysis in this study is qualitative. The results of the study concluded: 1) The notary's responsibility for making a certificate of inheritance that does not involve all heirs can be subject to civil liability, criminal liability, responsibility in carrying out his/her position towards the notary and responsibility for the code of ethics. The notary's responsibility in making a certificate of inheritance is seen depending on what errors are in the Deed of Inheritance made by the Notary. The responsibility of a notary is not limited to law alone, but can also be in the form of moral and ethical responsibility, so that in making a certificate of inheritance if the notary makes a mistake or takes actions that are detrimental to the parties or one of the interested parties, the notary must be morally and ethically responsible or fully responsible. 2) Legal protection for the parties for making a certificate of inheritance that does not involve all heirs is Repressive protection can be obtained by other heirs through complaints through court lawsuits, either criminal lawsuits or civil lawsuits. Legal protection for heirs in disputes over making a certificate of inheritance that does not involve all heirs, in addition to receiving repressive protection, actually also receives preventive protection. Preventive legal protection for land ownership rights holders is by registering the land.
Legal Implementation of the Validity of Electronic Certificates
Authors: Syabbani Maulana Zakki , Hasana Dahniarti
Published: December 2024

The implementation of land certificate digitalization from analog certificates converted into electronic certificates is carried out in stages and using a pilot project system. The readiness of both human resources and infrastructure must truly meet the required standards. However, the process of certificate digitalization in Indonesia cannot be denied considering that one of its goals is to minimize land disputes and legal protection for land object owners. This study aims to determine the extent of the implementation of the validity of electronic certificates after the issuance of the Regulation of the Minister of ATR/BPN Number 1 of 2021 concerning Electronic Certificates in Bantul Regency. The approach method used in this thesis is empirical juridical. The specifications of this study use descriptive analysis. The type of data used in this study is primary data which includesCivil Code,Basic Agrarian Law (UUPA) Law Number 11 of 2020 concerning Job CreationRegulation of the Minister of ATR Number 1 of 2021 concerning Electronic Certificates, as well as secondary data containing books and other supporting documents. Collection of research data using interview techniques and document studies or library materials. The data analysis method used in analyzing the data is a qualitative analysis of the interactive model as proposed. The results of the study show that: First, the implementation of land certificate digitalization in Indonesia is gradual. The Bantul ATR/BPN Office is still in the process of processing electronic certificates for Government Offices. Second: Each office of each ATR/BPN is expected to have prepared various aspects such as caution.
Sanctions of the Notary Supervisory Board of Banten Province Against Notaries Who Do Not Provide Services in Accordance with the Notary Law
Authors: Febrianto Rohman Dwi
Published: December 2024

This Notary Code of Ethics contains various matters related to the duties and authorities of Notaries in carrying out their profession and position as public officials. The material elements contained in this Notary Code of Ethics include obligations, prohibitions, exceptions and sanctions that will be imposed on Notaries who violate this Code of Ethics.This study aims to determine and analyze:1) To find out and analyze what kind of Notary can be said not to provide services in accordance with the provisions of the Notary Law; 2) To find out and analyze the form of Sanctions imposed by the Notary Regional Supervisory Board in Banten Province; and 3) To find out and analyze the basis for consideration of the Banten Province Regional Supervisory Board in imposing sanctions. The conclusion of the research results of the Banten Province Regional Supervisory Board imposes Sanctions on Notaries who Do Not Provide Services in Accordance with the Provisions of the Notary Law, the Notary Supervisory Board can impose sanctions on violators, the sanctions imposed on members of the Indonesian Notary Association who violate the code of ethics can be: Reprimand, Warning, Schorzing (temporary dismissal) from members of the association, Onzetting (dismissal) from members of the association, and Dishonorable Dismissal from members of the association. However, the dismissal sanction given to Notaries who violate the code of ethics is not in the form of dismissal from the notary position but dismissal from membership of the Indonesian Notary Association.
Notary's Responsibility in Carrying Out Official Secrecy Regarding the Contents of Deeds in Blora Regency
Authors: Azizah Siti Nurul
Published: December 2024

One of the very noble legal professions (officium nobile) is the Notary profession, it is said so because of the work done by a Notary. Notaries have the authority to make deeds which are regulated in Article 15 paragraph (1), (2) and (3) UUJN. Notaries need the principle of caution in carrying out their duties, because if there is an error or negligence from the Notary in carrying out his position, it can cause legal problems for the Notary in the future. Notaries in carrying out their positions are obliged to maintain the confidentiality of all matters concerning deeds and other letters that have been made, this is regulated in Article 16 paragraph (1) letter f regarding the obligation to deny. This research was written using an empirical research method and using a qualitative approach, studied with analytical descriptive research specifications. The results of this study are that the Notary's responsibility is stated in Article 65 UUJN which explains that he is responsible for every deed he makes. The responsibility held by a notary adheres to the principle of liability based on fault of liability. The responsibility of a notary arises if there is an error made in carrying out his/her duties and the error causes a loss to the person requesting the notary's services. If the notary makes a mistake, he/she may be subject to civil, criminal and administrative sanctions. In order for a notary to be able to provide information in court, he must have the approval of the Notary Supervisory Board. This is regulated in Article 66 of the 2014 UUJN.
Synergy between Land Deed Officials and the Regional Revenue Agency of Samarinda City Regarding Determination of Land and Building Sale and Purchase Transaction Values in Samarinda City
Authors: Salim Tandy Setiawan
Published: December 2024

This research aims to examine and analyze the form of synergy between PPAT and the Samarinda City Bapenda Office regarding determining the value of land and building sale and purchase transactions in Samarinda City and examine and analyze the obstacles and constraints that occur in the process of implementing BPHTB collection and determination regarding sale and purchase transactions at the Office. Bapenda Kota Samarinda This research is empirical legal research, namely legal research carried out by conducting field research by looking at and observing what happens in the field, the application of these regulations in practice in society. The results of the research explain that the Land Deed Making Officer (PPAT) is obliged to ask the parties the correctness of the BPHTB tax payment, if the parties as taxpayers cannot submit proof of BPHTB tax payment, because the taxpayer does not know the BPHTB tax and does not know how to calculate the BPHTB payment. , then the Land Deed Drafting Officer (PPAT) has the authority to assist taxpayers in calculating, assist taxpayers in carrying out BPHTB Verification, and supervise BPHTB tax payments made by the taxpayer
Legality of Credit Agreements with Fiduciary Guarantees made with Artificial Intelligence (AI)
Authors: Hanim Lathifah , Rinda Listyawati Peni , Noorman MS
Published: December 2024

Fiduciary Guarantee before being used as collateral in a credit agreement, it is mandatory to register the fiduciary first. Electronic fiduciary registration still has problems including network disruptions, system errors and is vulnerable to cyber attacks. Smart contract integration with electronic fiduciary guarantee registration can be a solution to these problems. Smart contract as a form of artificial intelligence / Artificial Intelligence (AI). The purpose of this study is to analyze the legality of credit agreements with fiduciary guarantees made with Artificial Intelligence (AI). The type of research used is empirical legal research, supported by primary and secondary data. The results of the research are that Smart contract is a computer program that can make agreements automatically with the blockchain system.AI is generally viewed as a legal object, not a legal subject. This is because AI is a tool or device used by humans to achieve certain goals. The requirements for the validity of an agreement (including a credit agreement with fiduciary guarantee) remain based on Article 1320 of the Civil Code.
Mitral Valve Surgical Treatment with Mini-Invasive Access (Five-Year Results)
Authors: Fylypchuk Vasyl V. , Lazoryshynets Vasyl V.
Published: December 2024

In the world, minimally invasive mitral valve surgery (MIMVS) has a recognized role in the surgical treatment of mitral valve (MV) diseases, however, this technique has not yet been widely used in our country. Due to the lack of clear clinical guidelines and recommendations in the choice of access to MV, many cardiac surgery centers implement a minimally invasive technique insufficiently often, and this procedure is characterized by complex learning curve.
The aim. To analyze the results of MV surgical treatment using a minimally invasive approach.
Materials and methods. Between 2020 and 2024, surgical treatment of MV insufficiency through a right-sided minithoracotomy was performed in 34 patients aged 18 to 67 at the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, forming the primary study group. The comparison group included 36 consecutive patients (aged 25 to 81) who underwent isolated MV insufficiency correction through the classic approach, i.e. median longitudinal sternotomy (between 2023 and 2024).
Results. The studied groups did not differ in terms of echocardiographic parameters. It was established that blood loss in the operating room was significantly higher with median longitudinal sternotomy compared to minithoracotomy (268.06 ± 14.3 mL and 192.50 ± 12.1 mL, respectively; p = 0.001). However, duration of operation and time of aortic compression were significantly longer in patients in the main group compared to controls, which is consistent with data from other researchers. Patients after minithoracotomy had a likely lower number of hours of analgesia, compared to those after median longitudinal sternotomy (88.35 ± 12.9 hours and 148.11 ± 16.6 hours, respectively; p = 0.009). Complications occurred less often in patients after minithoracotomy than in controls (8.8% and 11.1%, respectively; p > 0.05).
Conclusions. MIMVS was associated with less blood loss in the operative period and reduced the severity of early postoperative pain. The effectiveness of surgical treatment using MIMVS was 100%, while complications occurred less often than in controls.
Features of Myocardial Revascularization in Multifocal Atherosclerosis with Involvement of Coronary Arteries and Lower Limb Arteries
Authors: Gabriyelyan Artur V. , Cheveliuk Oleksandr V.
Published: December 2024

The presence of a combination of coronary artery disease (CAD) and peripheral artery disease (PAD) is associated with nearly double all-cause mortality rate, up to 4.6% per year, compared to the mortality rate for each of the conditions. Performing the first-stage intervention on the arteries of the lower limbs carries a high risk of the coronary blood flow worsening in the form of perioperative myocardial infarction, while isolated coronary artery bypass grafting (CABG) may exacerbate ischemia of the lower limbs. The following questions remain unresolved: What should be the sequence and timing of surgical interventions in the combination of CAD and PAD? Do simultaneous surgical interventions have advantages over staged interventions? What is the optimal graft choice for CABG? What is the optimal technique for myocardial revascularization?
The aim. To study the features of myocardial revascularization in patients with multifocal atherosclerosis affecting both coronary arteries and arteries of the lower limbs.
Materials and methods. We analyzed the treatment outcomes in 48 patients with combined coronary artery and lower limb artery disease from 2016 to 2023, as well as data from contemporary literature from 2018 to 2023, which covered over 14,000 patients. Surgeries were performed without cardiopulmonary bypass, both simultaneously and in stages. Venous and arterial grafts were used during the interventions.
Results. The patients who underwent simultaneous operations demonstrated a higher incidence of wound complications (p < 0.001). The patients who underwent staged procedures experienced more severe limb ischemia requiring intervention (p < 0.001) than those who had simultaneous procedures. No cases of acute cerebrovascular accidents were noted in either group. In both groups, early postoperative periods were marked by rhythm disturbances, specifically paroxysms of atrial fibrillation, which were successfully managed conservatively. There were no hemorrhagic complications associated with prolonged heparinization during simultaneous procedures compared to staged interventions. The patients who underwent either simultaneous or staged myocardial revascularization and vascular reconstruction of the lower limbs rarely experienced complications related to vascular graft thrombosis.
Conclusions. The choice of intervention sequence should prioritize CABG as the first step, both in simultaneous and staged interventions. Safe procedures for patients with multifocal atherosclerosis involving coronary and lower limb arteries require a multidisciplinary team. Simultaneous interventions help avoid ischemic complications associated with delaying the next stage of revascularization of other affected vascular territories. Delaying the revascularization of lower limb arteries in staged interventions may lead to the worsening of existing limb ischemia.
Extracranial Carotid and Vertebral Artery Dissection
Authors: Kobza Ihor I. , Mota Yuliia S.
Published: December 2024

Cervical artery dissection (CAD) is a rare vascular pathology that causes stroke in 2.0% of cases and is the most common cause of ischemic stroke among young patients. Today the choice of optimal treatment of CAD remains controversial, especially the issue of choosing antiplatelet and anticoagulant therapy, the expediency of endovascular and surgical approaches.
The aim. To analyze the results of management of extracranial carotid and vertebral artery dissection.
Materials and methods. Retrospective and prospective analysis of the results of comprehensive examination and treatment in 40 patients (17 [42.5%] men and 23 [57.5%] women, mean age 48.7 ± 13.4 years) with CAD was performed. Of these, 14 (35.0%) patients underwent surgical management, 26 (65.0%) received conservative treatment.
Results. Etiology of CAD included: atherosclerosis in 13 (32.5%), fibromuscular dysplasia in 12 (30.0%), trauma in 3 (7.5%), and nonspecific aortoarteritis in 1 (2.5%) patient. Spontaneous CAD was observed in 11 (27.5%) patients. The choice of surgical tactics in patients with carotid artery dissection was justified due to lesion of proximal extracranial segment with unstable ulcerative atherosclerotic plaque, critical stenosis, dissecting aneurysm. The choice of optimal anticoagulant and antiplatelet therapy in conservative group was predicted by individual approach, including the risk of bleeding and ischemic stroke. Long-term results were evaluated among 22 patients who received conservative treatment. Complete resolution of dissection was noted in 15 (68.2%), partial in 4 (18.2%), recurrence of dissection in 1 (4.5%) patient. In 9 (40.9%) patients, complete resolution of dissection was observed within 6 months of treatment.
Conclusion. The choice of anticoagulant and antiplatelet therapy of CAD requires an individual approach with evaluation of the risk of bleeding, ischemic stroke, duration of the disease, lumen recanalization, atherosclerotic lesion, patient’s comorbidity. Novel oral anticoagulants and their combination with antiplatelets allow to achieve effective results of treatment of CAD and prevent the recurrence of ischemic events.
Association of Microcirculation Parameters with Mortality in Patients with Coronary Artery Disease Combined with COVID-19
Authors: Netiazhenko Vasyl Z. , Mostovyi Serhii E. , Gurianov Vitalii G.
Published: December 2024

The aim. To investigate the association of microcirculation parameters with deaths in patients with coronary artery disease and COVID-19.
Materials and methods. From January 2020 to December 2022, 79 patients with coronary artery disease (CAD) without COVID-19, 127 patients with CAD and COVID-19, and 180 patients with COVID-19 without CAD were examined at the clinical sites of the Bogomolets National Medical University. The control group consisted of 37 healthy volunteers. Digital capillaroscopy (DC) was performed to assess the caliber and length of arterial and venous parts of the capillaries, as well as velocity of red blood cells therein. Laser Doppler flowmetry (LDF) was used to measure the microcirculation index and capillary blood flow reserve. Wavelet analysis of the basal LDF signal was also performed and the maximum amplitudes of fluxmotions were measured: endothelial, neurogenic, myogenic, respiratory, and cardiac. All the patients underwent transcranial Doppler monitoring to detect microembolic signals.
Results. The greatest damage to the microcirculatory bed was observed in patients with CAD and COVID-19. The risk of death was 6.3% in patients with CAD, 22% in those with CAD combined with COVID-19, and 6.1% in patients with COVID-19. According to the LDF, the risk of death increases at certain values of flux amplitudes, and according to the DC, with a decrease in capillary caliber and blood flow velocity. The index of mortality risk assessment was proposed with the consideration of amplitudes of neurogenic fluxmodes, caliber of venous part of the capillaries, velocity of red blood cells in arterial part of the capillaries, microcirculation index and presence of CAD and/or COVID-19.
Conclusions. In patients with CAD and COVID-19, deterioration of microcirculation regulation, decreased erythrocyte velocity and increased microembolic signals were found. It is proposed to use the index for assessing the risk of mortality in patients with COVID-19.
Endovascular Treatment of the Tentorial Dural Arteriovenous Fistulas. Case Series and Literature Review
Authors: Shchehlov Dmytro V. , Svyrydiuk Oleh Ye. , Chebanyuk Svitlana V. , Altman Igor V. , Sydorenko Olena F. , Vyval Mykola B. , Mamonova Maryna Yu.
Published: December 2024

Dural arteriovenous fistulas (DAVFs) are vascular anomalies where arteries from the carotid or vertebral arteries directly drain into the dural venous sinuses. Symptoms can range from asymptomatic to severe, including hemorrhage, venous hypertension, and neurological deficits. Tentorial dural arteriovenous fistulas (TDAVFs), a rare subset occurring in the tentorium, represent up to 4% of all DAVFs. Traditionally, DAVFs have been treated surgically, but recent advancements in endovascular embolization have made it a first-line treatment, although the optimal approach is still debated.
The aim. To evaluate the efficacy and outcomes of endovascular treatment for TDAVFs.
Materials and methods. Between 2012 and 2024, 174 patients with DAVFs were treated at the ScientificPractical Center of Endovascular Neuroradiology of the NAMS of Ukraine, including 8 patients with TDAVFs (mean age 58.5 years). All the patients with TDAVFs were symptomatic, with symptoms including hemorrhage (37.5%), headache, tinnitus, and seizures (62.5%). Endovascular treatment used liquid embolic agents and coils when required. Outcomes were assessed using postoperative angiograms and the modified Rankin Scale.
Results. Nine embolization sessions were performed; of these, 8 (88.9%) using n-butyl cyanoacrylate Histoacryl and 1 (11.1%) using Onyx. Complete shunt elimination was achieved in 75% of sessions; 25% had residual lowflow shunting, with vessels unsuitable for further catheterization. No neurological deterioration occurred. The mean length of hospital stay was 5.5 days. Follow-up angiography in 7 patients showed one case of symptom worsening and vessel recruitment, which was later fully treated with repeat transvenous embolization.
Conclusions. Endovascular embolization is an effective and safe treatment for TDAVFs. This case series indicates its efficacy but underscores the need for further randomized trials to compare all treatment modalities for tentorial and other deep-seated dural vascular lesions.
Reverse Left Ventricular Remodeling after Aortic Valve Replacement for Aortic Disease: TAVR and Minimally Invasive Cardiac Surgery
Authors: Telehuzova Oleksandra V. , Stychynskyi Oleksandr S.
Published: December 2024

The aim. To examine the difference in left ventricular (LV) reverse remodeling parameters in elderly patients (65 years and more) who underwent transcatheter aortic valve replacement (TAVR) and minimally invasive cardiac surgery aortic valve replacement (MICS-AVR).
Materials and methods. This study analyzed data from a consecutive series of 159 patients who underwent TAVR (n = 109) and MICS-AVR (n = 50) due to severe or critical aortic stenosis between January 2018 and August 2023. We also included the data from follow-ups: 30 days, 60 days and 1 year after replacement.
Results. Five deaths (4.0%) occurred during the follow-up period of 3.1 ± 2.0  years. The causes of late death were stroke (n = 2), sepsis, interstitial pneumonia, and cancer. The 6-year survival rate was 86.0% and the 6-year freedom from cardiac death rate was 93.8%. After 1  year (1.3 ± 0.6  years) of follow-up, postoperative left ventricular ejection fraction increased significantly from 48.5 ± 19.6% to 55.4 ± 7.2% (p < 0.0001), LV end-systolic dimension index decreased significantly from 29.3 ± 11.8 to 18.5 ± 3.1 mm/m2 (p < 0.0001). Specifically, LV end-diastolic dimension decreased from 65.4 ± 22.6 mm to 60.84 ± 0.21 mm (p = 0.023) in the TAVR group vs. 67.3 ± 22.4 mm to 62.99 ± 0.29 mm (p = 0.204) in the MICS-AVR group. There was a steady and significant improvement in post-procedural LV septal thickness in both groups at different evaluation times. There was also a slight but significant improvement in LV dimensions (LV end-diastolic dimension and LV end-systolic dimension) in the TAVR group at 1 year compared with the MICS-AVR group.
Conclusion. Favorable long-term outcomes, including 6-year freedom from cardiac mortality and no need for reoperation, were similar in both groups. Both TAVR and MICS-AVR are effective treatments for patients with aortic stenosis, allowing for the potentiation of postoperative LV remodeling and achieving satisfactory long-term outcomes and improved quality of life.
Evaluation of 2-formylphenylboronic and 3-chlorophenylboronic acid derivatives for in vitro cytotoxicity and cell migration
Authors: Yenice Gürsu Bükay , Yılmaz Öztürk Betül , Dağ İlknur
Published: December 2024

Wound treatment and skin regeneration is a complex process, and non-healing wounds pose a major socioeconomic burden in terms of health. Effective and alternative approaches are needed for successful wound management. Although boranic acid derivatives have been reported to have positive and strong effects on wound healing, phenyl substituted boranic acid derivatives can be used as more regenerative and effective compounds in healing. In this study, the in vitro cytotoxic effects of 2-formyl phenyl boronic acid and 3-chloro phenyl boronic acid on L929 fibroblast cell lines were investigated by WST-8 analysis and their wound healing effects were investigated by cell migration test. Our data reveal concentration-dependent effects of both boranic acid derivatives. For 2-formyl phenyl boronic acid, dosage applications between 3.90-31.25 µg/ml showed a viability of 84 % and above, and at higher concentrations the viability was found to be 5-10 %. For 3-chloro phenyl boronic acid, a viability rate of 64-109 % is observed as a result of dosage applications between 3.90-250 µg/ml, while the percentage of viability decreases to 17 % at a concentration of 500 µg/ml. Cell migration test data show that the effects of phenyl boronic acid (PBA) derivatives in terms of cell migration increase as time increases, and the effect of 2-formyl phenyl boronic acid at the 24th hour is quite effective in terms of cell migration. Since the wound healing effect of PBA derivatives is concentration dependent, it should be taken into consideration that the use of high concentrations may be toxic.
Bor katkılı BNT-6BT piezoseramik toz takviyeli PVDF kompozitlerin üretimi ve karakterizasyonu
Authors: Tıkız Serhat , Özgül Metin
Published: December 2024

Piezoelektrik malzemeler, mekanik enerjiyi elektrik enerjisine ve tersinir olarak da elektrik enerjisini mekanik enerjiye dönüştürme kabiliyetleri sayesinde otomotivden sağlığa kadar pek çok sektörde; sensör, aktüatör ve transdüser gibi uygulamalar için yoğun ilgi görmektedir. Çevreci ve yenilenebilir enerji üretiminin büyük önem kazandığı günümüzde, yeni geliştirilen piezoelektrik malzemeler pek çok alanda ideal çözümler sunmaktadırlar. Nanomalzemeler ve karakterizasyon tekniklerinde yaşanan ilerlemeler de araştırmacılara yenilikçi yaklaşımlar geliştirme imkânları sunmaktadır. Son yıllarda artan çevre duyarlılığı ile birlikte Pb içerikli malzeme kompozisyonlarına alternatif benzer üstün özellikli malzeme geliştirilmesi araştırmaları önemli çıktılar ortaya koymuştur. Bu çerçevede bu çalışmada, en yaygın kullanılan Pb içerikli kurşun zirkonat titanat (PZT) seramiklere benzer yapı ve özellikler sunan 0,94(Bi0,5Na0,5)TiO3-0,06BaTiO3 BNT-6BT piezoseramiklerin bor (B+3) katkılı tozlarının üretimi ve bu tozların poliviniliden florür (PVDF) polimerinde kullanımı ile üstün özellikli hafif ve esnek kompozitlerin üretimi amaçlanmıştır. Hidrotermal yöntemle üretilen piezoseramik tozların karakterizasyonu x-ışını difraksyonu (XRD) ve taramalı elektron mikroskobu (SEM-EDX) analizleri ile gerçekleştirilmiştir. Piezoseramik tozlar, PVDF polimerine katkı maddesi olarak eklendikten sonra elektroeğirme yöntemiyle fiber yapılar oluşturulmuştur. Fiberlerin morfolojisi SEM-EDX teknikleri, piezoelektrik özellikleri sağlayan β fazındaki değişim ise Fourier dönüşümlü kızılötesi spektroskopisi (FT-IR) gibi detaylı analizlerle incelenmiştir. Elde edilen sonuçlar, bor katkılı piezoseramik tozların PVDF polimerine eklenmesiyle piezoelektrik özelliklerde iyileşmeler sağlandığını göstermektedir.
Pengembangan e-modul berbasis etnomatematika untuk mengembangkan keterampilan literasi numerasi di sekolah dasar
Authors: Astuti Dwi , Wibawa Sutrisna , Zulfiati Heri Maria
Published: December 2024

Penelitian ini bertujuan untuk (1). Mengembangkan E-modul berbasis etnomatematika, (2) mengetahui kelayakan E-modul, dan (3) mengetahui efektivitas penggunaan E-modul untuk pengembangan keterampilan literasi numerasi. Instrumen yang digunakan adalah tes dan non tes, teknik pengumpulan data menggunakan wawancara, lembar observasi, angket, dan tes. Teknik analisis data menggunakan teknik analisis data kualitatif dan kuantitatif. Subjek penelitian adalah siswa SDN Banjarharjo Tanjungsari. Metode penelitian ini menggunakan penelitian dan pengembangan (R&D) dengan model ADDIE (Analyze, Design, Development, Implementation, Evaluation). Validasi E-modul dilakukan oleh ahli media, ahli materi dan pengguna yaitu guru. Hasil penelitian ini adalah (1) produk yang dihasilkan berupa E-modul berbasis etnomatematika dengan budaya rasulan di Gunungkidul, (2) E-modul berbasis etnomatematika dinyatakan layak berdasarkan hasil validasi oleh 2 orang expert yaitu ahli media dan ahli materi serta seorang pengguna yaitu guru. Rerata perolehan skor dari 2 validator materi adalah 96,88% dengan kategori sangat layak. Rata-rata perolehan skor dari 2 validator media adalah 81,5% dengan kategori layak untuk digunakan dalam pembelajaran, dan (3) berdasarkan hasil uji efektivitas menggunakan SPSS 23, diperoleh rerata posttes kelas Eksperimen sebesar 92,73 sedangkan hasil posttes kelas kontrol sebesar 80,00 artinya E-modul berbasis etnomatematika efektif meningkatkan keterampilan literasi numerasi siswa di sekolah dasar.
Hubungan Tingkat Kecemasan Dengan Timbulnya Acne vulgaris Pada Mahasiswa
Authors: Puspaciwi Sanisca , Indah Widyaningsih  , Rini Purbowati
Published: December 2024

Latar Belakang: Salah satu penyakit kulit yang paling sering ditemukan pada anak muda adalah jerawat. Masalah jerawat akan berdampak buruk bagi mental penderitanya. Tujuan: Penelitian ini bertujuan untuk Menganalisis dan mengetahui hubungan tingkat kecemasan dengan timbulnya Acne vulgaris pada mahasiswa pendidikan dokter di Universitas Wijaya Kusuma Surabaya angkatan 2020-2021. Metode: Penelitian ini menggunakan desain penelitian observasional analitik cross sectional, Populasi dalam penelitian ini yaitu seluruh mahasiswa Fakultas Kedokteran Universitas Wijaya Kusuma Surabaya angkatan 2020-2021 sebanyak 156 mahasiswa. Teknik pengambilan sampling  yaitu purposive sampling, dengan perhitungan rumus slovin, sehingga jumlah sampel sebanyak 70 responden. Penelitian menggunakan data primer dan analisis yang digunakan adalah uji chi square. Hasil: berdasarkan nilai p-value didapat nilai 0,003 (p-value<0,05) artinya terdapat hubungan antara tingkat kecemasan dengan timbulnya Acne vulgaris mahasiswi aktif Fakultas Kedokteran Universitas Wijaya Kusuma Surabaya Angkatan 2020-2021Kesimpulan: Hasil penelitian menunjukkan bahwa Tingkat kecemasan pada mahasiswa pendidikan dokter Universitas Wijaya Kusuma Surabaya Angkatan 2020-2021 sebagian besar dalam kategori tinggi. Gambaran terjadinya Acne vulgaris pada mahasiswa Ilmiah Universitas Wijaya Kusuma Surabaya angkatan 2020-2021 sebagian besar dalam kategori sering. Terdapat hubungan tingkat kecemasan dengan timbulnya Acne vulgaris pada mahasiswa pendidikan dokter di Universitas Wijaya Kusuma Surabaya angkatan 2020-2021.
Pengaruh Kontrol Rutin terhadap Kesembuhan pada Penderita Tuberkulosisi Paru di Puskesmas Lontar Kecamatan Sambikerep Kota Surabaya
Authors: Athalia N. Vionita  , Muzaijadah Retno Arimbi  , Mira Kusuma Wardhani
Published: December 2024

Pendahuluan: Secara global, tuberkulosis termasuk dalam 10 penyakit pembunuh terbesar. Terdapat 10 juta kasus tuberkulosis pada tahun 2018, dengan 1,5 juta kematian disebabkan oleh penyakit tersebut. Tujuan: Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh kontrol rutin terhadap kesembuhan pada penderita Tuberkulosis Paru di Puskesmas Lontar Kecamatan Sambikerep Kota Surabaya. Metode: Metode penelitian kuantitatif nominal dipakai dalam riset ini. Metode penelitian yang dipakai adalah metode survey cross sectional yaitu pengumpulan data dilakukan secara retrospektif melalui observasi rekam medis untuk memberikan gambaran mengenai pengobatan pasien Tuberkulosis (TB) dan evaluasi hasil dari pengobatan tersebut. Hasil:  Berdasarkan hasil uji Rank Spearman yang didapat dari program komputer SPSS 20.0 for windows nilai p-value yang didapatkan adalah p = 0,00 yang menunjukan bahwa ada hubungan antara kontrol rutin terhadap kesembuhan pada penderita tuberkulosis paru. Hasil dari koefisien korelasi didapatkan kesembuhan pasien TB paru tidak hanya dipengaruhi oleh kepatuhan mereka dalam rutin kontrol ke puskesmas, tetapi juga oleh berbagai faktor pendukung lainnya.  Kesimpulan: Pasien yang melakukan kontrol rutin secara teratur menunjukkan tingkat kesembuhan yang lebih tinggi dibandingkan dengan pasien yang tidak melakukan kontrol secara konsisten. Hal ini menunjukkan pentingnya pemantauan berkala dalam mendukung kepatuhan pasien terhadap pengobatan dan meminimalkan risiko resistensi obat.
Hubungan Antara Pengetahuan Tentang Penyakit Infeksi Dengan Status Imunitas Mahasiswa
Authors: Susmitha Eva , Dorta Simamora
Published: December 2024

Latar Belakang: Penyakit infeksi merupakan salah satu masalah dalam bidang kesehatan yang dari waktu ke waktu terus berkembang. Salah satu Upaya meningkatkan imunitas dengan meningkatkan pengetahuan dan berperilaku sehingga terhindar dari penyakit infeksi Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan tentang penyakit infeksi dengan status imunitas pada mahasiswa FH UWKS angkatan 2022. Metode: Penelitian ini termsuk dalam penelitian observasional yang bersifat crosssectional. Populasi pada penelitian ini adalah mahasiswa Fakultas Hukum UWKS angkatan 2022 (120 gmahasiswa) Penentuan jumlah sampel dalam penelitian ini menggunakan rumus Slovin yaitu sebanyak 93 mahasiswa, dengan teknik simple random sampling. variabel bebas (independent) dalam penelitian adalah pengetahuan tentang penyakit infeksi dan variabel terikat (dependent) dalam penelitian berikut adalah adalah status imunitas. Teknik analisis data menggunakan chi square. Hasil: Hasil penelitian menyimpulkan bahwa mahasiswa FH UWKS Angkatan 2022 memiliki Tingkat pengetahuan tentang penyakit infeksi dalam kategori tinggi yaitu sebesar 58,1% atau 54 responden, Status imunitasnya juga sebagian besar berkategori sangat baik yaitu sebesar 84,9% atau 79 responden. Kesimpulan: Penelitian ini juga menunjukkan bahwa  terdapat hubungan yang kuat  antara pengetahuan tentang penyakit infeksi dengan status imunitas pada mahasiswa FH UWKS Angkatan 2022, kedua variabel tersebut dalam kategori kuat dengan nilai 0,611.
DRAFT OF THE UPDATED VERSION OF THE STRATIGRAPHIC CODE OF UKRAINE (2012) ON TYPES OF STRATIGRAPHIC SCALES AND SCHEMES, AS WELL AS RULES FOR THE PREPARATION AND APPROVAL OF STRATIGRAPHIC SCHEMES
Authors: Vernyhorova Yu.V.
Published: December 2024

Definitions of the concepts “stratigraphic scale” and “stratigraphic scheme”, outlining the scope of their application, establishing the rules for their preparation and the procedure for approval are set out in the provisions (articles) of the current Stratigraphic Code of Ukraine (Stratigraphic…, 2012, see Section 4, pp. 30–31 and Annex 3, pp. 39–42; after this referred to as SCU-2012). This ensures the unification/standardization of stratigraphic information that is mandatory for use in any scientific stratigraphic research and geological survey work on the territory of Ukraine. The analysis of the relevant articles of the 2012 edition of the SCU-2012 has shown that they need to be improved.
The basis of this development is the principle of imitation: to preserve the general content of the stratigraphic classification and nomenclature, the updated texts of Section 4 and Annex 3 retain the information contained in the SCU-2012 and its previous editions. That is the terms and content of individual articles, if possible, have been left unchanged (or taken as a basis with minor changes) from previous editions of the Stratigraphic Code (Stratigraphic…, 1977, 1988; Stratigraphic…, 1997, 2012), as well as from the International Stratigraphic Guide (https://stratigraphy.org/guide/). In addition, new separate formulations and provisions were proposed by the current state of development of stratigraphic classification and nomenclature and based on the author’s own experience of conducting stratigraphic studies and participating in geological surveys, e.g., Anistratenko et al., 2006, 2012; Vernyhorova et al., 2009, 2012; Vernyhorova, 2014–2016.
Thus, the main changes and additions to Section 4 “Stratigraphic scales and schemes” and Annex 3 “Rules for drawing up and approval of stratigraphic schemes” of the current Stratigraphic Code of Ukraine, 2012 are as follows:

the structure of Section 4 has been updated: all definitions of “stratigraphic scale” (and its types), and “stratigraphic scheme” (and its types) are collected exclusively in this section, Fig. 1;
the structure of Annex 3 has been updated: it contains only the rules for the preparation and approval of stratigraphic schemes, Fig. 2;
the existing provisions set out in Section 4 and Annex 3 of the SCU-2012 were partially corrected;- some provisions from the previous editions of the Stratigraphic Code, which remain relevant and are used in stratigraphic research in Ukraine, were added to the texts;
the rules for drawing up and approving stratigraphic diagrams (Annex 3), especially in terms of graphic design of stratigraphic schemes, explanatory notes, and rules for approving stratigraphic schemes were expanded;
two figures from the graphic design of scaled and non-scaled stratigraphic schemes were added.
Bir Orta Çağ Düşünürü Olarak Dante ve Seküler Düşünceye Katkısı
Authors: Işık Alper
Published: December 2024

İtalyan düşünür Dante, yaşadığı dönemde papalık, imparatorluk ve şehir devletlerinin güç mücadelesine tanık olmuş ve bunun sonucunda yaşadığı şehir olan Floransa’dan sürgün edilmiştir. Sonrasında gösterdiği çabalar, düşünürün Floransa’ya geri dönmesini sağlamamış ve sürgünde hayatını kaybetmiştir. Dante bu sürgün döneminde hem edebi hem de felsefi alanda önemli eserler kaleme almıştır. Bu eserlerden De Monarchia (Monarşi), papalık ve imparatorluğun birbirlerine karşı üstünlük iddialarını, tarihsel olayları da ele alarak değerlendirmekte ve yaptığı tespitlerle her iki iktidarın da meşruiyetini ayrı ayrı Tanrı’dan aldığını ortaya koymaktadır. Dante bu görüşleriyle seküler düşünceye kapı aralayan düşünürlerden bir olarak kabul edilmektedir. Ayrıca Dante bu eserde papalığın üstünlüğü için ortaya atılan iddiaları çürütmeye çalışırken, aynı zamanda evrensel bir monarşinin dünya barışı için zorunluluk olduğunu da öne sürmektedir.
Ensuring academic integrity in the age of ChatGPT: Rethinking exam design, assessment strategies, and ethical AI policies in higher education
Authors: Evangelista Edmund De Leon
Published: December 2024

The rapid advancement of artificial intelligence (AI) technologies, particularly OpenAI’s ChatGPT, has significantly impacted higher education institutions (HEIs), offering opportunities and challenges. While these tools enhance personalized learning and content generation, they threaten academic integrity, especially in assessment environments. This study systematically examines the impact of ChatGPT on academic integrity in HEIs, focusing on exam design, assessment strategies, AI detection tools, and policy frameworks. This research draws from current literature and expert recommendations to identify practical approaches for developing assessments that foster critical thinking and deep cognitive engagement, making them less susceptible to AI-generated content. Key areas explored include the creation of complex, analytical exam formats, deploying advanced AI detection software to counter AI-assisted cheating, and formulating institutional policies that promote the ethical use of AI. This comprehensive framework aims to equip educators and administrators with practical strategies to preserve academic standards while harnessing the potential benefits of AI, ensuring the continued validity of assessments in the AI-driven educational landscape.
Mitigating Supply Chain Vulnerabilities: A Bibliometric Analysis of Sustainable Logistics for Resilience and Risk Management with Perspectives on the Automotive Industry
Authors: Abdelaziz Shereen , Munawaroh Munjiati
Published: December 2024

In a world increasingly shaped by global disruptions—ranging from pandemics and natural disasters to geopolitical tensions—the integration of sustainable logistics practices and supply chain resilience has become a cornerstone of modern supply chain strategies. This study undertakes a bibliometric analysis of 445 Scopus-indexed documents (2002–2024) using VOSviewer and Biblioshiny, offering a systematic exploration of critical research trends, thematic clusters, and knowledge gaps within this intersection. The analysis identifies several dominant themes, including green logistics, circular economy principles, digital transformation technologies, and adaptive risk management. Findings highlight the transformative role of digital tools—such as blockchain, IoT, and AI—in enhancing supply chain transparency, predictive analytics, and operational agility. The automotive sector emerges as a focal industry, facing unique challenges of resource dependency, regulatory compliance, and the need to align sustainability with resilience frameworks. Additionally, the study underscores the growing prominence of circular economy practices, such as reverse logistics and closed-loop supply chains, in addressing environmental goals while bolstering supply chain adaptability. However, significant gaps persist, particularly in the empirical validation of sustainable logistics practices and their measurable impact on resilience outcomes across diverse regions and sectors. The study calls for the development of integrated frameworks that align environmental sustainability with technological innovation and operational efficiency, supported by longitudinal studies and cross-industry comparisons. This research contributes to academic discourse by offering actionable insights for scholars and practitioners. It establishes a foundational roadmap for integrating sustainability and resilience, emphasizing the pivotal role of digitalization and circular economy principles in shaping robust, adaptable supply chains capable of withstanding the complexities of an increasingly volatile global environment.