bluuebunny/crossref_metadata_2025 huggingface dataset:
My father’s Pitcairn
Authors: Scheckter John
Published: March 2021

This examination of personal correspondence reveals not only how material exchanges were established between a small Pacific island and a burgeoning superpower, but also how a discourse network developed to support a friendly, informative relationship over 35 years. In 1958, my father, Spencer Scheckter, in New Jersey, United States, began a correspondence with John and Bernice Christian, on Pitcairn Island, that lasted until Bernice died in 1993. As the manager of a small-town department store, my father asked practical questions and solved logistical problems. A small trade developed: Spencer sent clothing and machine parts, and the Christians returned wood carvings and other souvenirs. The discourse network revealed in the material exchange rarely permits emotional depth or complexity, so that its shape is readily apparent – and its boundaries as well. On Pitcairn, the time period of the correspondence will later come under legal scrutiny, beginning in 1997, with allegations of rape and sexual abuse that eventually came to trial in 2004. While the investigations implicated the entire culture of the island, the Christians’ bounded discourse offers, perhaps more usefully, a clear picture of the complicated, interwoven negotiations that ageing individuals were required to perform in a small, closed society.
Applying MCDM Technique in analyzing the effect of promotion items based on online shopping factors
Authors: Ajripour Iman
Published: March 2021

Developing technology causes companies in a market to compete with each other in challenging ways. In addition to a holistic marketing concept which focuses on the needs of target markets and delivering superior value, marketing should be adapted with new technology to fulfill consumer needs. Although many strategies have been introduced for marketing, digital marketing or marketing 4.0 is a new generation of marketing that engages with the audience through digital tools. These days, online shopping is only too popular among consumers. Many factors which affect customer decision during online shopping have been explored. In this paper, the effect of promotion items in online shopping will be explained. The main aim of this paper is to apply a multi-criteria decision-making technique in prioritizing eleven promotion items by considering five online customer shopping criteria. The novelty of this paper is to apply PROMETHEE II (Preference Ranking Organization METHod for Enrichment of Evaluations) in analyzing the effect of promotion items based on online shopping criteria. PROMETHEE II completely prioritizes discrete alternatives. A case study is conducted in a home appliance company in Iran.
A hazai víz- és csatornamű-üzemeltetési piac feltárása, a víz és csatornaközművek árazási, árszabályozási gyakorlatának vizsgálata
Authors: Bárdos Pál Péter , Nagy Balázs , Tóth Andrea
Published: March 2021

Jelen cikk központi témája a hazai víziközmű-piac jellegzetességeinek ismertetése. A szerzők tanulmányukban az árazási kérdésekre fókuszáltak, emellett részletesen vizsgálták a hazai piac működésével kapcsolatos paramétereket, mint például a víziközmű-vagyon tulajdonlása, a jelenlegi támogatási rendszer, valamint a vonatkozó jogszabályok. Az árazási módszertanok, valamint a hazai gyakorlat összevetését követően, részletesen ismertetik a szerzők által feltárt piaci problémákat, és végül az azokra javasolt lehetséges megoldásokat.
Gazdasági kórkép alulnézetből I. rész (Syndrome of Hungarian Economy from Bottom-view – I. part)
Authors: Pitti Zoltán
Published: March 2021

A rendszerváltás utáni időszak gazdasági teljesítményei a beteljesült remények és a megvalósulatlan várakozások egymást követő hullámzásait takarják. A mögöttünk hagyott két évtized első felét a gazdasági szerkezetváltás, a piaci kapcsolatok módosulása, valamint új – többségében külföldi – befektetői csoportok megjelenése jellemezte, amelyek együttes hozadéka volt a gazdaság stabilizálódása, majd az új növekedési pályára állás. Az ezredfordulót követő évtized első felére azonban a külföldi befektetésekre alapozott gazdaságfejlesztési stratégia erejét vesztette, s a helyettesítésre szánt hazai kkv-szektor – a kiemelt támogatások és a kedvezmények ellenére – nem tudott a növekedés motorjává válni. Szerzőnk – a BCE tudományos kutatója és az APEH korábbi elnöke – a versenyszektor 2000–2008. évi pénzügyi beszámolói alapján a hazai vállalkozások demográfiai, teljesítményi és eredményességi jellemzőit vizsgálja, s két részből álló tanulmányában arra keresi a választ, hogy a várakozásoktól elmaradó működési eredményekben milyen szerepe lehet a gazdaságfejlesztési stratégia hiányának, a vállalkozási teljesítmények elégtelenségének, a tőkehiánynak, illetve a pénzügyi rendszer torzulásainak. Szerkesztőségünk a tanulmányt olyan vitaindítónak tekinti, ami széles érdeklődésre tarthat számot, s szívesen vállalkozunk arra, hogy közreadunk minden jobbító szándékú gondolatot. _______ The economic performance during the transition period was characterized by the alternations of fulfilled hopes and unrealized expectations. The economic restructuring and changes in market relations took place during the first decade, while new – mostly foreign – investment groups entered on the new market. As a result the economy was stabilized and was put to a new growth path. But after the millennium the foreign investment based economy development strategy was no more adequate. The new engine for the growth should have been the domestic small and medium enterprise sector (SME), but despite the subsidies this sector was not strengthened to take this role. The author – the researcher of BCE, and the ex-president of APEH – analyses the characteristics of the domestic business demography, performance and effectiveness, based on the 2000–2008 annual financial statements of the business sector. The two-part study seeks the reason for the disappointing operation results. What role take in this phenomena the absence of economic strategy, the deficiency of business performance, the lack of capital and the financial distortions of the system. Our editorial intend this study as a debate for the public, and we would publish the ideas which improves this relevant topic.
Racionális és intuitív döntéshozók Kaliforniában és Magyarországon (Analysis or Intuition – Strategic decision making in California and Hungary)
Authors: Zoltayné Paprika Zita
Published: March 2021

Stratégiai döntéseket jellemzően a vállalatok felső vezetői, vezérigazgatók és elnökök hoznak. Ennek szellemében a szerző negyven felső vezetőt kérdezett meg két nagyon különböző régióban (Kaliforniában és Magyarországon) egy összehasonlító kutatás keretében. A két országban tizenkét válaszadó vezérigazgató, elnök, alelnök vagy felelős vezető volt (rájuk mint Vezetőkre hivatkoztunk), miközben nyolcan alapítói és többségi tulajdonosai voltak saját vállalkozásuknak (őket nevezzük Vállalkozóknak). A kutatás három területre irányult: 1) Hogyan hoznak döntéseket a felső vezetők a valóságban a világ e két különböző táján 2) Mennyiben különböznek – ha egyáltalán különböznek – a Vállalkozók és a Vezetők az alkalmazott döntéshozatali közelítésmódot tekintve, amikor az analitikus gondolkodást az intuícióikkal kombinálják 3) Mik a hasonlóságok és a különbségek a menedzsmentképességekben és a döntéshozatali rutinokban a Vállalkozók és a Vezetők között a vizsgált menedzsmentkultúrákban? ______ Strategic decision making is usually conducted by a firm’s top management, led by the CEO or the President of the company. In keeping with this, 40 top level managers in two very different regions (California, USA and Hungary) were targeted in a comparative research study. In the two countries, twelve of the managers were CEOs, Presidents, Vice Presidents or Chief Officers (hereafter referred to as Executives) while eight were founders and majority owners of their own enterprises (hereafter referred to as Entrepreneurs). The research focused on the following 3 areas: 1) How top level managers really make strategic decisions in these two different parts of the world; 2) How Entrepreneurs and Executives differ, if at all, in their approach to strategic decision making when they combine analytical thinking with their intuition; 3) The similarities and differences in management skills and decision making routines between Entrepreneurs and Executives within the investigated management cultures.
Formação para a Atenção Primária à Saúde
Authors: Torres Peixoto Marcelo , Cerqueira Miranda Adriana , Torres Peixoto Marcio
Published: March 2021

A Emergência da pandemia da Covid-19 reforçou a importância da Atenção Primária à Saúde – APS. No Brasil, o Sistema Único de Saúde ­­– SUS ainda carece de recursos humanos com perfil adequado para trabalhar neste nível de atenção, por isso, existe a necessidade de mudanças na formação. No começo do século, a adoção de novas Diretrizes Curriculares Nacionais – DCN buscou a readequação no perfil do egresso, com a valorização de expertises necessárias para atuação no SUS/APS. Os objetivos deste artigo foram correlacionar as DCN de cursos da área de saúde (Educação Física, Enfermagem, Fisioterapia, Medicina, Nutrição, Odontologia, Psicologia, Serviço Social e Terapia Ocupacional) em relação à abordagem sobre a APS e incitar o debate sobre as necessidades de readequação da formação profissional no pós-pandemia. Para a análise tomou-se como base os atributos da APS e diretrizes comuns para a graduação em saúde segundo o Conselho Nacional de Saúde ­– CNS. A maioria das DCN sinaliza a formação profissional voltada para as necessidades do SUS, fortalecendo o trabalho em equipe para a busca da integralidade, reconhecem o processo saúde-doença-cuidado num contexto ampliado e estimulam diferentes metodologias no processo ensino-aprendizado. A formação interprofissional, o trabalho colaborativo, a avaliação processual e a longitudinalidade do cuidado foram elementos pouco abordados pelas diretrizes. As DCN de Educação Física, Psicologia e Serviço Social foram as que menos abordaram elementos referentes aos atributos da APS. Por fim, as DCN precisam ser revistas para a se adequaram aos pressupostos comuns para a graduação em saúde propostos pelo CNS.
PNE 2014-2024 e a redução das desigualdades regionais:
Authors: Ferreira Suely , Moraes Karine Nunes de , Oliveira João Ferreira de
Published: March 2021

O artigo tem como objetivo analisar a meta 12 do PNE (2014-2024), particularmente os indicadores da taxa líquida e bruta de matrícula da educação superior e problematizar as assimetrias inter e intrarregional de seu acesso. A pesquisa é do tipo exploratório e documental, considerando os dados levantados no âmbito do Projeto Integrado de Pesquisa “Expansão e qualidade da educação superior no contexto do Plano Nacional de Educação (2014-2024): Tensões, limites e perspectivas”, financiado pelo CNPq. O estudo evidencia a necessidade de um grande esforço nacional para alcançar a meta 12 e que esse esforço precisa ser ainda maior nas regiões Norte e Nordeste.
Amassando o barro
Authors: Ferreira Tatiana Aparecida Pezetta , Pinto José Marcelino de Rezende
Published: March 2021

A qualidade dos professores, intimamente associada à remuneração, é fator decisivo na qualidade do ensino. No entanto, no Brasil, prevalece ainda a desvalorização desses profissionais, seja pela baixa remuneração, seja pela carreira pouco atrativa. Assim, o presente estudo faz uma análise de três municípios do interior paulista no contexto do Fundeb, considerando as relações existentes entre a remuneração, os gastos com educação, além de outros indicadores. Embora sejam municípios próximos e com similaridades, os resultados indicam diferenças importantes na remuneração e na carreira que se relacionam com o gasto/aluno, mas também com fatores como o grau de municipalização, a dependência frente ao Fundeb, a presença de convênios com a rede privada e o tamanho do município.
Fundeb
Authors: Davies Nicholas
Published: March 2021

O artigo pretende avaliar alguns aspectos do Fundo de Manutenção e Desenvolvimento da Educação Básica e de Valorização dos Profissionais da Educação (Fundeb) com base na legislação e em bibliografia pertinente. Constata que (1) ele traz pouco dinheiro novo (a complementação federal, correspondente a 10% da receita nacional); (2) em muitos casos, não possibilita a melhoria salarial dos profissionais do magistério pois os 60% vinculados a isso se baseiam apenas na receita do Fundeb, prejudicial aos governos que perdem com o Fundeb, e não na receita total vinculada à educação; (3) são frágeis e/ou pouco claros os critérios dos fatores de ponderação dos vários níveis e modalidades de ensino; (4) a legislação é inconsistente e privatizante; (5) o número de matrículas e escolas estaduais e municipais na educação básica caiu de 2007 a 2019.
Novo Fundeb
Authors: Castoni Remi , Cardoso Monica Aparecida Serafim , Cerqueira Leandro de Borja Reis
Published: March 2021

O artigo busca refletir acerca do futuro do novo Fundeb e as perspectivas para o financiamento da educação básica, visto que, para além de um direito, a educação é também um investimento. Por tal razão, a Constituição estabelece, como condição indispensável, a disponibilidade de recursos financeiros necessários para que cada ente da federação possa oferecê-la com qualidade. Com recorte na discussão atual do novo Fundeb, será abordado o resultado desse processo ocorrido nas duas casas legislativas (Câmara e Senado), alicerçado em mais de três anos de debate público, com a promulgação da Emenda Constitucional n.º 108/2020 e, consequentemente, a consolidação do Fundeb como política permanente, inscrita na Constituição Federal com um desenho aprimorado.
A regulamentação da lei do Novo Fundeb
Authors: Soares Marina Gleika Felipe , Silva Samara de Oliveira , Almeida Lucine Rodrigues Vasconcelos Borges de , Soares Lucineide Maria dos Santos
Published: March 2021

O artigo objetiva analisar os desafios e perspectivas da regulamentação do Novo Fundeb, nos PL nº 4372/2020 e PL nº 4519/2020; apresentar as principais conquistas contidas na atual EC 108/2020 e identificar as principais dificuldades e potencialidades que vêm emergindo na regulamentação da lei. O estudo tem abordagem qualitativa, por meio da pesquisa documental de fontes primárias e de referências bibliográficas centrais Carreira e Pinto (2007), Ximenes e Pinto (2019), Freitas (2020). Os resultados informam que a sociedade precisa estar vigilante ao processo de regulamentação do Novo Fundeb, que precisa ser detalhado em uma agenda de lutas, para poder se materializar.
A descentralização financeira dos recursos públicos para a Educação Básica e a Política de Fundos
Authors: Corrêa Frederico , Carvalho Fabrício Aarão Freire
Published: March 2021

Este artigo apresenta um estudo bibliográfico sobre a política de descentralização financeira dos recursos da educação instituída a partir dos anos 90 no Brasil, relacionando-a a política de fundos implementada a partir da Lei nº 11.494/2007 a qual constituiu o Fundo de Manutenção e Desenvolvimento da Educação Básica e Valorização dos Profissionais da Educação (FUNDEB). Acreditamos que discussões acerca deste tema são pertinentes, pois apresentam diferentes conceitos da política de descentralização e, como ela, em determinados momentos, assumiu um caráter de desconcentração, pois entendemos que a União em muitos momentos transferiu a Estados e Municípios autonomia parcial para a execução de ações, concentrando ainda decisões condizentes a gestão financeira em sua esfera hierárquica.
Direitos sociais em risco
Authors: Silva Maria Vieira , Richter Leonice Matilde , Souza Vilma Aparecida
Published: March 2021

No contexto atual, presenciamos recorrentes processos que produzem colapsos nos direitos sociais conquistados por meio de incessantes e históricas lutas da sociedade civil. No campo da educação pública, os acintes têm sido agudizados de forma reiterada, sobretudo no que concerne à redução de recursos ou disputa pelos fundos públicos. Enquanto elaboramos esse editorial, em 24 de fevereiro de 2021, diferentes associações acadêmicas e sindicais realizam manifestações contrárias à Proposta de Emenda Constitucional (PEC) n. 186 (BRASIL, 2019), de autoria do senador Marcio Bittar, a qual compromete a manutenção dos dispositivos constitucionais de vinculação de recursos da receita de impostos para a educação no âmbito da União, dos estados, do Distrito Federal e dos municípios. De fato, isso impacta negativamente as ações do Estado brasileiro na ampliação e priorização dos investimentos para garantir o direito inalienável à educação.
Mining Bug Report Repositories to Identify Significant Information for Software Bug Fixing
Authors: Luaphol Bancha , Polpinij Jantima , Kaenampornpan Manasawee
Published: March 2021

Most studies relating to bug reports aims to automatically identify necessary information from bug reports for software bug fixing. Unfortunately, the study of bug reports focuses only on one issue, but more complete and comprehensive software bug fixing would be facilitated by assessing multiple issues concurrently. This becomes a challenge in this study, where it aims to present a method of identifying bug reports at severe level from a bug report repository, together with assembling their related bug reports to visualize the overall picture of a software problem domain. The proposed method is called “mining bug report repositories”. Two techniques of text mining are applied as the main mechanisms in this method. First, classification is applied for identifying severe bug reports, called “bug severity classification”, while “threshold-based similarity analysis” is then applied to assemble bug reports that are related to a bug report at severe level. Our datasets are from three opensource namely SeaMonkey, Firefox, and Core:Layout downloaded from the Bugzilla. Finally, the best models from the proposed method are selected and compared with two baseline methods. For identifying severe bug reports using classification technique, the results show that our method improved accuracy, F1, and AUC scores over the baseline by 11.39, 11.63, and 19% respectively. Meanwhile, for assembling related bug reports using threshold-based similarity technique, the results show that our method improved precision, and likelihood scores over the other baseline by 15.76, and 9.14% respectively. This demonstrate that our proposed method may help increasing chance to fix bugs completely.
Formación Profesional: base para el crecimiento personal y el desarrollo social
Authors: Arenas Alonso Antonio
Published: March 2021

Nuestra Formación Profesional, continuadora de las escuelas de artes y oficios del siglo XIX, como el espacio de formación en las ocupaciones que más personas demandan, no ha conseguido alcanzar su plena aceptación social, ya que se sigue considerando como puerta de abandono del camino principal (Bachillerato/universidad). Considerando la capacidad para el trabajo como valor del ser humano, se propone revalorizar la Formación Profesional configurándola como parte de un camino que, de forma lógica y razonable, finaliza en la universidad.
Reframing the Debate on Quality vs Quantity in Research Assessment
Authors: Pal Jiban K.
Published: March 2021

The debate on quality versus quantity is still persistent for methodological considerations. These two approaches are highly contrasting in their epistemology and contrary to each other. A single composite indicator that reasonably senses both quality and quantity would be significant toward performance. This paper evaluates the potency of the combined metric for quality assessment of publications (QP) in India’s National Institutional Research Framework (NIRF) exercise in 2020. It also suggests a potential improvement in quality measurement to obtain the rankings more rationally with finer tunings.
Ranking of Institutions of Higher Education
Authors: Nassa Anil Kumar , Arora Jagdish
Published: March 2021

Ranking of higher education institutions (HEI) is a convenient and easily understandable method of evaluation and assessment. An ordinal number assigned to an HEI by a ranking system represents its comparative position in a list of ranked institutions based on marks obtained by it on various performance parameters or indicators. Ranking of HEIs have been lauded and criticised simultaneously. University rankings are often criticised for methodology used, choice of indicators and weightage assigned to them, focus on science, technology and English language publications, assessment of institutions as whole (instead of individual program) and the practice of assigning an ordinal number or a rank to represent quality of an HEI. At the same time, university rankings are lauded for serving as information tools for students, researchers, funding agencies, policy makers and other stakeholders as well as for instilling a competitive spirit amongst institutions to perform better in ranking systems. However, most experts agree that rankings are here to stay in the education market place. As such, although ranking system cannot measure quality of education and research in absolute term, it does serve as indicator to various aspects of quality in higher education, which, in turn, can be used by institutions themselves for improving their performance on these parameters. While universities are welcomed to use rankings for improving their performance, ranking systems should not dictate university policy, either at a national or institutional level, but should be used as a source of information for guiding policies that should be decided according to the needs of the university’s own community, traditions, market niche, national role and so on1.
Low-Velocity Impact Properties of Polyurethane Composites Reinforced with Warp-Knit Spacer Fabric
Authors: Chen Si
Published: March 2021

Eight kinds of polyurethane (PU)-matrix composite samples were prepared by impregnating the warp-knit spacer fabrics with flexible PU foam. An impact test was carried out to investigate the influence of fabric structure parameters on the compression behaviors and energy-absorption efficiency of the composites. By using finite element (FE) analysis and ANSYS software, the unit cell models of the composites were built to simulate the impact responses and get strain-stress curves. Comparison of FE simulation and experimental curves showed good consistency between them.
Studium jednej metafory
Authors: Ronge Gerard
Published: March 2021

Tekst jest recenzją książki Barbary Kaszowskiej-Wandor Res publica (post) litteraria. Od poetyki wspólnoty do postliteratury. Badanie etymologii metafory „republiki literackiej” prowadzi autorkę do rozważania fundamentalnych pytań dotyczących roli literatury w kształtowaniu wspólnot społecznych i pytań o sposoby wywierania przez literaturę wpływu na rzeczywistość polityczną. Rozległa erudycja badaczki i stosowane przez nią odważne rozwiązania metodologiczne pozwalają jej udzielić na te pytania – bardzo stare i często uważane za nierozstrzygalne – oryginalnych, nieoczywistych odpowiedzi.
O kwestii oryginału, przekładu autorskiego i adaptacji. Wokół polskiej i angielskiej wersji Antygony w Nowym Jorku Janusza Głowackiego
Authors: Amenta Alessandro
Published: March 2021

Janusz Głowacki’s internationally acclaimed tragicomedy inspired by Sophocles’ Antigone has been the subject of intense debate and misinterpretations. The article aims to demonstrate that the play was primarily written in Polish, and that the English version is an adaptation/rewriting made by the author in collaboration with the American screenwriter Joan Torres. Furthermore, it shows that the English version was created while the writing of the Polish text was still in progress, so that the former influenced and left clear traces in the latter, questioning the traditional hierarchy between the original and the translated or adapted text.
Effect of alkali bases on the synthesis of ZnO quantum dots
Authors: Zhang Xilian , Luo Shanshan , Wu Xiaodan , Feng Minghui , Li Yingying , Han Haoyun , Li Wenkui
Published: March 2021

The surface-modified zinc oxide quantum dots (ZnO QDs) have broad application prospects in the field of biomedicine because of their good water solubility, dispersibility, and high fluorescence stability. The alkali bases play important roles in controlling the morphology, size distribution, dispersity, and fluorescence intensity of the synthesized ZnO QDs. In this article, ZnO QDs were synthesized to induce hydrolysis–condensation reaction. The influences of alkali bases (LiOH, NaOH, and KOH) and the ratio of n(Zn2+):n(OH−) on the properties of synthesized ZnO QDs were investigated. The results show that the particle size of the ZnO QDs prepared using LiOH and NaOH as raw materials are smaller than that using KOH. ZnO QDs prepared at the ratio of n(Zn2+):n(LiOH) = 1:1 have the best fluorescence performance and dispersibility.
Input/output inconsistencies of daily evapotranspiration conducted empirically using remote sensing data in arid environments
Authors: Elhag Mohamed , Bahrawi Jarbou , Boteva Silvena
Published: March 2021

The reliable quantification of daily evapotranspiration (ET) over vast croplands is a quest in many scholarly works aimed at the precise practice of water resources management. Remote sensing–based empirical and nonempirical models were developed to overcome large-scale quantification issues, which are usually experienced when using conventional approaches for the estimation of ET. The surface energy balance system (SEBS) model was used to quantify the daily ET in the arid/semi-arid over Wadi Ad-Dwaser, Saudi. SEBS input variables are parametrically sensitive and climatic dependent, and the model input/output dependencies are of high comprehensibility; therefore, the optimization analysis of SEBS input/output parameters is the target of the current research. SEBS inputs reciprocal inconsistencies were determined using the artificial neural network analysis, while the output dependencies on the daily ET estimation were mapped. Results demonstrated that the temperature and relative humidity are the most sensitive parameters to be considered in the routine crop monitoring procedure. SEBS output thematic maps showed the robust proportional correlation between the daily ET and the conducted temperature map. Moreover, the estimated daily ET was inversely correlated with the estimated cold sensible heat fluxes. The findings suggest systematic monitoring and forecasting procedures for efficient water-saving management plans in Saudi Arabia.
Positional dependency in Murrinhpatha: expanding the typology of non-canonical morphotactics
Authors: Nordlinger Rachel , Mansfield John
Published: March 2021

Principles of morphotactics are a major source of morphological diversity amongst the world’s languages, and it is well-known that languages exhibit many different types of deviation from a canonical ideal in which there is a unique and consistent mapping between function and form. In this paper we present data from Murrinhpatha (non-Pama-Nyungan, northern Australia) that demonstrates a type of non-canonical morphotactics so far unattested in the literature, one which we call positional dependency. This type is unusual in that the non-canonical pattern is driven by morphological form rather than by morphosyntactic function. In this case the realisation of one morph is dependent on the position in the verbal template of another morph. Thus, it is the linearisation of morphs that conditions the morphological realisation, not the morphosyntactic feature set. Positional dependency in Murrinhpatha thus expands our typology of content-form interactions and non-canonical morphotactics with implications for our understanding of morphological structure cross-linguistically.
Nanoparticles Enable Efficient Delivery of Antimicrobial Peptides for the Treatment of Deep Infections
Authors: Deng Yingxue , Huang Rui , Huang Songyin , Xiong Menghua
Published: March 2021

Antimicrobial peptides (AMPs) have emerged as promising alternatives of traditional antibiotics against drug-resistant bacteria owing to their broad-spectrum antimicrobial properties and low tendency to drug resistance. However, their therapeutic efficacy in vivo, especially for infections in deep organs, is limited owing to their systemic toxicity and low bioavailability. Nanoparticles-based delivery systems offer a strategy to increase the therapeutic index of AMPs by preventing proteolysis, increasing the accumulation at infection sites, and reducing toxicity. Herein, we will discuss the current progress of using nanoparticles as delivery vehicles for AMPs for the treatment of deep infections.

Statement of significance

Antimicrobial peptides (AMPs) are rarely directly used to treat deep infections due to their systemic toxicity and low bioavailability. This review summarizes recent progress that researchers employed nanoparticles-based delivery systems to deliver AMPs for the treatment of deep infections. Nanoparticles-based delivery systems offer a strategy to increase the therapeutic index of AMPs by preventing proteolysis, increasing the accumulation at infection sites, and reducing toxicity. Especially, the development of intelligent nanocarriers can achieve selective activation and active target in the infectious sites, thus improving the therapeutic efficacy against bacterial infection and reducing the toxicity against normal tissues.
A Comprehensive Review of Acne Vulgaris
Authors: Mohiuddin AK
Published: March 2021

Acne, also known as acne vulgaris (AV), is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin. It is characterized by blackheads or whiteheads, pimples, oily skin, and possible scarring. An intact stratum corneum and barrier, normal natural moisturizing factor and hyaluronic acid levels, normal Aquaporin-3 (AQP3) expression (localized at the basal lateral membranes of collecting duct cells in the kidney), and balanced sebum secretion are qualities of the skin that fall in the middle of the oily–dry spectrum. Patients rarely, if ever, complain about reduced sebum production, but elevated sebum production, yielding oily skin that can be a precursor to acne, is a common complaint. Several factors are known to influence sebum production. AV is mostly triggered by Propionibacterium acnes in adolescence, under the influence of normal circulating dehydroepiandrosterone (DHEA). It is a very common skin disorder which can present with inflammatory and noninflammatory lesions chiefly on the face but can also occur on the upper arms, trunk, and back. Age, in particular, has a significant and well-known impact, as sebum levels are usually low in childhood, rise in the middle-to-late teen years, and remain stable into the seventh and eighth decades until endogenous androgen synthesis dwindles. Sebum, the oily secretion of the sebaceous glands containing wax esters, sterol esters, cholesterol, di- and triglycerides, and squalene, imparts an oily quality to the skin and is well known to play an important role in acne development. Acne can’t be prevented or cured, but it can be treated effectively. The pimples and bumps heal slowly, and when one begins to go away, others seem to crop up. Depending on its severity, acne can cause emotional distress and scar the skin. Acne may cause scarring of the skin, but generally causes no long-term health problems. In self-body image, some parts of the body including face play an important role. Existence of even a minor lesion in this part may be unpleasant for the patient and seems large. This image can cause mental disorders including depression and anxiety, low self-esteem, and decrease in social relationships. However, high levels of anxiety and depression in patients with facial acne are not related to oxidative stress, according to a study published online in the Journal of Cosmetic Dermatology
Transient Acantholytic Dermatosis (Grover's Disease) in a Bulgarian Patient Associated With Idiopathic Low-Grade Thrombocytopenia: First Description in the Medical Literature!
Authors: Tchernev Georgi , Stavrov Konstantin , Wollina Uwe , Temelkova Ivanka
Published: March 2021

Grover’s disease is a transient acantholytic dermatosis that usually disappears within a few weeks, but it can also be presented as a persistent variant with a duration of more than 3 years. The etiology of this disease is not entirely clear and possible causes include viral infections, drug reactions (BRAF inhibitors and allogeneic haematopoietic stem cell transplantation). In terms of treatment, topical and systemic steroids, oral vitamin A and PUVA therapy are described. We present a 79-year-old man with a 1-month complaint for a recurring, highly itchy, blistering rash on the skin of the upper limbs, back and chest. During the clinical examination, there was an erythemo-papulo-vesicular polymorphic rash , in places with xerosis areas, engaging the upper part of the trunk, as the initial data and subsequent histopathological verification data spoke undoubtly in direction of acantholytic dermatosis or Grover’s disease .During hospitalization, systemic antihistamine and topical steroid therapy was performed. Subsequently, ambulatory therapy with Acitretin 20 mg /daily per os and Methylprednisolone aceponate 0.1% x 2 / daily topically was given with a good therapeutic response. We believe that this case seems to be the first officially documented case of Morbus Grover associated with idiopathic low-grade thrombocytopenia. Key words: Morbus Grover; Idiopathic thrombocytopenia; Acitretin; Prednisolone; PSA
Atypical Presentation of Lichen Planopilaris: Presentation of Two Cases and Review
Authors: Okwundu Nwanneka , Ekpo Felicia , Ghaferri Jessica , Fivenson David
Published: March 2021

Lichen Planopilaris (LPP) is an uncommon scalp disorder of unknown etiology and prevalence. It is thought to be an autoimmune process triggered by unknown genetic and/or environmental factors that attack hair follicles of the scalp. LPP has been reported to mimic or present in association with various autoimmune diseases and immunomodulatory therapies. We present two atypical case of LPP in Caucasian patients; the first is a patient with generalized pruritus, skin eruptions, and scalp hair loss. Biopsy of the lesions revealed exocytosis of atypical lymphocytes at the Dermo-Epidermal Junction (DEJ) and formation of small Pautrier’s microabscesses in the interfollicular epidermis as well as a robust lymphocytic inflammatory infiltrate with destruction of perifollicular appendages. This led us to the diagnosis of LPP-like Folliculotropic Mycosis Fungoides (FMF). The second case is a patient with a history of Systemic Lupus Erythematosus (SLE) who presented clinically with perifollicular erythema and alopecic patches, with loss of follicular ostia on the frontal and vertex scalp and evidence of follicular tufting. Histologically, she had decreased number of follicles with a peri-infundibular lymphocytic infiltrate and vacuolization at the Dermoepidermal Junction (DEJ) and there was also thickening of the basement membrane highlighted with a periodic acidic Schiff stain. This led to a diagnosis of SLE/LPP overlap. Keywords: Lichen Planopilaris (LPP); Cicatricial; Alopecia; Frontal Fibrosing Alopecia (FFA), Folliculotropic Mycosis Fungoides (FMF), Lichen Planus (LP).
Vesicant Dermatitis due to PaederusSp.: Short Communication
Authors: Moreira Amorim Gustavo , Whitaker Letícia Dall’Oglio , Lúcio Isadora Vicência , Molozzi Bruna , Reuwsaat Paul Ingrid , Amorim Filho Roberto Moreira
Published: March 2021

We present a very illustrative case of dermatitis caused by Paederus sp affecting a 3 year old healthy boy in the countryside of Brazil. The appearing of painful bullous lesions with clear content in a linear arrangement occurred suddenly, and was later diagnosed to be caused by the beetle popularly known in Brazil as “Potó” which predominate in rural areas. Treatment was realized only with local hygiene with antiseptics and dressing in the eroded areas, in addition to oral acetaminophen. The patient evolved with complete cure of the lesions. We also present a brief review of vesicant dermatitis by Paederus sp. Keywords: Blister Beetle Dermatitis; Paederus Dermatitis; Irritant Contact Dermatitis.
Pseudoporyphyria Associated with Lemon Water and Naproxen
Authors: Okwundu Nwanneka , Moesch John , Belden Sarah
Published: March 2021

Background: Pseudoporyphyria is an uncommon bullous dermatosis. It shares clinical and histological features with porphyria cutanea tarda, but it occurs in the absence of porphyrin metabolic dysfunction. It is characterized by skin fragility, bullae, milia, and scarring on the dorsum of the hands and other sun-exposed areas. Case: We present a patient on naproxen with recurrent pseudoporyphyria of the dorsal hands associated with the consumption of lemon water. Findings: Biopsy showed a pauci-inflammatory sub epidermal vesicle with caterpillar bodies and laboratory studies lacked any urine or serum porphyrin abnormalities. The cutaneous lesions were noted to resolve with discontinuation of the consumption of lemon water. Keywords: Pseudoporyphyria; Porphyrin; Porphyria Cutanea Tarda; Chlorophyll; Vesicle and Depigmented
3D Printing of Human Microbiome Constituents to Understand Spatial Relationships & Shape Parameters in Bacteriology
Authors: Izard Jacques , Gerbaba Teklu Kuru , Yumul Shara R. P.
Published: March 2021

Effective laboratory and classroom demonstration of microbiome size and shape, diversity, and ecological relationships is hampered by a lack of high-resolution, easy-to-use, readily accessible physical or digital models for use in teaching. Three-dimensional (3D) representations are, overall, more effective in communicating visuospatial information, allowing for a better understanding of concepts not directly observable with the unaided eye. Published morphology descriptions and microscopy images were used as the basis for designing 3D digital models, scaled at 20,000×, using computer-aided design software (CAD) and generating printed models of bacteria on mass-market 3D printers. Sixteen models are presented, including rod-shaped, spiral, flask-like, vibroid, and filamentous bacteria as well as different arrangements of cocci. Identical model scaling enables direct comparison as well as design of a wide range of educational plans.
Dreamscapes and Escapedreams
Authors: Alexander Bryant Keith
Published: March 2021

Using the artwork of Southern-born but Los Angeles-based artist Jerry Weems, this performative autoethnography engages artistic renderings of Black Southern cultural life as lived and historicized; as nostalgia and hauntology; as remembrance and recovery; between the there-and-then and the here-and-now. All of this invokes my own lived experience as a Black man from the South now living in Los Angeles.
An Implementation of Reflective Pedagogy in Hybrid Music Learning of Gamelan Soepra
Authors: Pamungkas Benidiktus Candra , Utomo Udi , Sumaryanto Florentinus Totok
Published: March 2021

Gamelan Soepra is a gamelan instrument that has been changed in tonality to diatonic and has a higher wadhah. With its diatonic tonality, Gamelan Soepra is able to be combined with today's modern instruments and it is able to play many song. The uniqueness of the Gamelan Soepra was used by Pater van Deinse as a music education at SMA Kolese Loyola. Gamelan Soepra is a tool for educating thar is combined with reflective pedagogy as an educational method. Reflective pedagogy has several elements, namely: context, experience, reflection, action, and evaluation. This study aims to understand the implementation of the reflective pedagogy elements in the learning process of Gamelan Soepra. The methods used by the author in collecting data were observation, interview, and document study. Gamelan Soepra Learning through reflective pedagogy not only develops students' abilities in playing music (Competence), but students also are trained to hone and develop their conscience (Compassion), conscience and their commitment and responsibility to what they have chosen (Commitment). This s is study expected to be a reference for developing learning methods, especially music learning
The Inheritance of Balo-Balo Art at the Cahaya Rembulan Musik Studio in Tegal City
Authors: Pratama Rizki Giska , Hartono Hartono , Triyanto Triyanto
Published: March 2021

The aim of this study is to analyze the inheritance of the balo-balo art performance and the inheritance of socio-cultural values carried out by the balo-balo art community. The method used is qualitative with ethnomusicology and anthropology approaches. The data collection techniques was conducted through observation, interviews, and documentation studies. The analysis process consists of data collection, data reduction, and data clarification. The results of the study on the inheritance of the balo-balo art include inheritance of the form of balo-balo art performance which was an effort to keep traditional arts. The inheritance was carried out at the Cahaya Rembulan Musik Studio by doing exercises, preparations, and balo-balo art performance. Balo-balo art poetry is in the form of wangsalan (poem) which contains of advice about God Almighty. The inheritance of socio-cultural values contain religious values which these values are contained in the lyrics and educational values that are inherited through training in balo-balo art which are expected to introduce traditional arts, especially balo-balo art to the Tegal City community.
A PROCICLICIDADE DO SISTEMA BANCARIO EN ESPAÑA. ESTUDO DESCRITIVO DO COMPORTAMENTO DO NEGOCIO BANCARIO PERANTE O CAMBIO DE CICLO
Authors: PISÓN FERNÁNDEZ Irene Clara , PUIME GUILLÉN Félix , CRESPO CIBRÁN Miguel Ángel
Published: March 2021

O estudo pretende analizar o grao de prociclicidade do negocio bancario e arelación entre os efectos da crise bancaria e a crise financeira. As conclusións extraídas daanálise empírica do sistema bancario no período anterior e posterior ao comezo da criseconfirman que o tratamento da xestión do risco bancario e do crédito deberá incluír non só aconsideración de variables afectas ao debedor, senón todas aquelas vencelladas á economíaen xeral.
O MERCADO DE CAPITALES EN AMÉRICA LATINA 1990-2013
Authors: ANDRADE RODRÍGUEZ Bernabé , BANDA MORA Ana del Pilar , GÓMEZ WALTEROS Jaime Alberto
Published: March 2021

Neste ensaio analízase o mercado de capitais en América Latina e procúrase amosar aevolución que tivo ao longo do período abranguido entre 1990 e 2013, atopándose unhafeble evolución que se corresponde a un desenvolvemento vencellado principalmente aoproceso especulativo e non ao sector produtivo, o cal implica un baixo impacto sobre aprodución e o desenvolvemento económico.
THE DETERMINANTS OF MIGRATION PROSPECT : SPATIAL ECONOMETRIC APPLICATION TO THE MOROCCAN DATA
Authors: IBOURK Aomar
Published: March 2021

The adepts of international migration have attempted to develop models that can be usedto examine the underlying factors that push the migrants to take the decision of leavingthe country of origin. The have tried to analyse the way in which the difference in thesocioeconomic determinants between spatial entities (countries, regions and provinces)may affect the decision of people to immigrate. This work has recommended first to verifyempirically the validation of the theory of migratory basins within one country and toidentify variables that clarify the intent of emigration. With respect to the Moroccancontext, this work presents a two-fold interest. On the methodological level, thiscontribution is, to our knowledge, the first application of the micro econometric spatialapproach on the data collected during our investigation. At the analytical level, thefindings of this work complement those of the few descriptive studies. Subsequently, theresults of this research should be used to reflect deeply upon the public policies related toemigration.
A TRAMITACIÓN AMBIENTAL DE NOVOS ESTABLECEMENTOS NA COMUNIDADE AUTÓNOMA GALEGA DESPOIS DA LEI 9/2013 DO EMPRENDEMENTO E DA LEI 21/2013 DE AVALIACIÓN AMBIENTAL
Authors: BLANCO SILVA Fernando , LÓPEZ DÍAZ Alfonso
Published: March 2021

No ano 2013 aprobáronse a Lei 21/2013, do 9 de decembro, de avaliación ambiental e a Lei9/2013, do 19 de decembro, do emprendemento e da competitividade económica de Galicia,que supoñen un cambio na normativa para a formulación de novos establecementos nestaComunidade, en función do impacto ambiental que provocarán; a estes dous documentosnormativos debénselle engadir a necesidade do cumprimento da Lei 16/2002, do 1 dexullo, de prevención e control integrados da contaminación para actividades que emitanelevadas cantidades de gases contaminantes. Neste artigo realizamos unha análise dastres leis, así como unha explicación de como resulta o procedemento de autorización denovos establecementos na actualidade na Comunidade Autónoma de Galicia.
Colorful Online Learning Problem of Early Childhood Education During the Covid-19 Pandemic
Authors: Munastiwi Erni
Published: March 2021

This research aims to determine the various problems of online learning at the level of early childhood education units during the COVID-19 pandemic. As for the issues among them, teachers have not all mastered IT; students tend to get bored too long studying at home. Likewise, parents are not ready to change the role of teachers at home and the policies of the central government and local governments and other issues.  This research uses a qualitative approach. Respondent consists of a teacher of 12 people and a parent of 25 people. Research location in Ponorogo Regency, East Java. The process of retrieving data using questionnaires through a google form. The results showed there were colorful problems, including 1) communication between educators, parents, and protégés, 2) the lack of costs for procurement of information technology facilities, and the price for online learning needs, 3) the right online learning method for early childhood. While the obstacles faced by parents are 1) mastery of material submitted to the child, 2) less growing the interest of the child, 3) internet network problems, 4) time accompanying the child to study online.
Current Status of Viral and Phytoplasma Diseases Affecting Gerbera Cultivation and Their Management
Authors: Gautam K. K. , Kumar S. , Raj S. K.
Published: March 2021

Gerbera (Gerbera jamesonii) is a popular ornamental plant cultivated all over the world. It is grown in beds, pots and used as cut-flower in making bouquets and for decoration in ceremonial functions. Gerbera has been commercially cultivated by a large number of growers in India as a primary source of income, therefore, has high socioeconomic impact in floriculture industry. The gerbera cultivation areas in India are increasing day by day due to its uses and the market demands. Its cultivation has been hampered by a variety of diseases that affect its flower quality and quantity. Of them, the viral and phytoplasma diseases cause considerable losses in gerbera cultivation. In this review, we have described about the disease symptoms, detection methods and identification of causal virus and phytoplasma pathogens affecting gerbera production worldwide and their disease management strategies opted by the researchers for production of pathogen-free plants.