bluuebunny/crossref_metadata_2025 huggingface dataset:
The Analysis of The Effectiveness of Pulmonary Tuberculosis and HIV-Co-TB Treatment Therapies at Sulianti Saroso Infectious Diseases Hospital
Authors: Andayani Nurita , Maninda Raise , Marlina Rosa , Noviantani Qoina , Qalalwa Khaled
Published: November 2023

Mycobacterium tuberculosis causes Tuberculosis (TB), an infectious disease. The study aims to evaluate DOTS therapy's impact on pulmonary TB and TB-HIV patients. This research used a descriptive qualitative study design with a retrospective descriptive research approach using secondary  data for the period June 2017 to July 2020. The analysis uses the Miles and Huberman model. A study of 305 people found that 83% of pulmonary TB cases completed treatment within the initial phase, 64% completed the continuation phase. TB-HIV cases 93% completed treatment within the initial phase, 71% the continuation phase. The combination of OAT and ARV doses was successful in reducing initial smear conversion in pulmonary TB cases. The treatment was evaluated as cure in pulmonary TB cases, complete in pulmonary TB-HIV cases, and had no treatment failure status in both groups. Treatment success in pulmonary TB patients was not significantly related (p-value≥5%) with the type of OAT, type of PMO, gender, and age. Whereas in HIV co-infected pulmonary TB patients, treatment success was significantly related (p-value <5%) with the type of PMO, and not related (p-value≥5%) with the type of OAT, gender, and age.
In-Vitro Antibacterial Activity of Excoecaria cochinchinensis Lour's Methanol Extract and Its Combination with Commercial Drugs
Authors: Nurhasana Devi , Febriansyah Rahmaga , Avidlyandi Avidlyandi , S. Salprima Yudha , Banon Charles , Oktiarni Dwita , Adfa Morina
Published: November 2023

The purpose of this study was to look into the antibacterial activity of methanolic extract of Excoecaria cochinchinensis as well as the effect of its combination with antibiotics on the growth of Klebsiella pneumoniae, Enterobacter aerogenes, and Staphylococcus epidermidis. The antibacterial activity test was carried out using the well diffusion method, and the combined effect of the extract and antibiotics was observed using the paper strip diffusion method. At various concentrations (25, 50, 75, 100, 150, 200, and 250 mg/mL), the extract significantly inhibited the growth of K. pneumoniae, E. aerogenes, and S. epidermidis. The inhibitory zone's diameter increased proportionally with the extract concentration. The growth of K. pneumoniae and S. epidermidis was then classified as extremely sensitive (+++) to the addition of the extract at 200 and 250 mg/mL concentrations, meanwhile, E. aerogenes’s with 250 mg/mL of the extract. Secondary metabolites such as oleanolic acid, arjunolic acid, scopoletin, kaempferol, quercetin, diterpenoid compounds, tannins, and other phenolics have been reported from E. cochinchinensis leaves and are thought to be responsible for its antimicrobial activity. The effect of the extract’s combination with antibiotics was insignificant compared to their individual activity, thereby classifying them as indifferent.
Hypoglycemia Incidence Rate in National and Non-National Health Insurance of Type 2 Diabetes Patients in COVID-19 Pandemic at Central Borneo
Authors: Veryanti Putu Rika , Sartika Ratu Ayu Dewi , Sauriasari Rani , Elya Berna , Puspitasari Rara Merinda
Published: November 2023

Community activity restrictions during the COVID-19 pandemic in Indonesia impact the quantity and quality of health services for type 2 diabetes (T2DM). This limitation could increase the risk of hypoglycemia in type 2 diabetes patients. The study aimed to compare the incidence rate of hypoglycemia between national (NHIP) and non-national health insurance participants (N-NHIP) with T2DM during the COVID-19 pandemic in Indonesia. The study used a cross-sectional design and was conducted at a government hospital in Central Borneo. Data was collected by consecutive sampling from September to November 2021. Sixty-two participants were divided into two groups (NHIP and N-NHIP groups). Each group consisted of 31 participants. They were interviewed regarding their experience with hypoglycemia in the last three months. The incidence rate of hypoglycemia in N-NHIP was higher than in NHIP (93.55% vs. 87.10%; p>0.05). Hypoglycemia is mostly presented in patients using a combination of short-acting and long-acting insulin. The incidence rate of hypoglycemia in T2DM during the COVID-19 pandemic in Central Borneo was relatively high. In future studies, it is necessary to analyse the factors that significantly affect the incidence of hypoglycemia in the population of T2DM patients in Indonesia.
TURNOVER INTENTION IN THE CEMENT INDUSTRY: A mediating model evaluation for future mitigation
Authors: Yanti Rini Adri , Rivai Harif Amali , Lukito Hendra
Published: November 2023

In the industrial sectors, retaining millennial employees by optimizing organizational support and suitability of workload is important to maintain the company's existence through human resources management, especially in the cement industry which requires employees with high-level integrity due to heavy work intensities. Therefore, this study was conducted to analyze and determine the effect of perceived organizational support and workload on turnover intention, by using the mediating contribution of job satisfaction to permanent millennial employees in one of the cement industries in Indonesia. Recorded, as many as 100 permanent millennial employees from various departments have participated. In terms of feedback data responses, were analyzed with the assistance of IBM SPSS software and Smart-PLS's latest version. Results found that fifth-relationships are in line with the research expectations while not to the other two. A quantitative approach with an explanatory design was used, in which the data were collected through online method distribution with the assistance of Google-form questionnaires. In the techniques of analysis, this study uses Smart-PLS software's latest version to assist the structural equation model (Average Variance Extracted > 0,5, Composite Reliability > 0,7, HTMT < 0,85, and R-square > 0,33), and second-order path-analysis (T > 1,96 & P ≤ 0,05) while IBM SPSS latest version used to descriptive analysis.
Effectiveness of investment in business acquisition: Results of disclosures 2021–2022
Authors: Tsekhomskiy N. V. , Tikhomirov D. V. , Rusinov D. A.
Published: November 2023

Aim. To perform an assessment of the performance of investments in business acquisitions over the years to 2021 by analyzing the impairments recognized in 2021 and 2022.

Objectives. To examine the possible approaches to analyze the performance of mergers and acquisitions; to elaborate on one of the approaches in the aspect of investigating the impairment of goodwill previously recognized as a result of company acquisitions; to analyze the indicators of available financial statements of companies for 2021 and 2022.

Methods. The study is based on the analysis of consolidated financial statements of Russian companies and sample data on foreign companies. We considered individual transactions on foreign companies’ exit from the Russian market and assessed the effect of their influence on the financial statements of foreign companies.

Results. The authors have carried out a post facto evaluation of the indicators of the largest Russian companies in the sample, assessed the possibilities of goodwill recovery as a result of M&A transactions. As a result of the analysis the conclusion is formed that the situation in the considered sector of economy remains stable. Meanwhile, foreign investors who have left the Russian market recognize significant impairment of investments in their financial statements.

Conclusions. The prospect for further research is to conduct a more extensive analysis based on a larger sample of companies. In 2023, some companies that preferred not to publish their 2022 financial statements have started to disclose their financial results again. This provides an opportunity to continue the research begun in the paper on the results obtained and to make further refinements.
Approaches to assessing the scientific potential of the region from the point of view of ensuring economic security
Authors: Shirokova E. A. , Yurinskaya Ya. V.
Published: November 2023

Aim. To assess the state of the scientific potential of the Magadan Oblast from the point of view of its influence on the formation of economic security of the region.

Objectives. To define the concept of “scientific potential of the region” and reveal its structure; to consider the existing approaches to assessing the scientific potential of the region; to conduct a comparative analysis of the scientific potential of the Magadan Oblast and the Far Eastern Federal District (FEFD).

Methods. The scientific potential of the region is considered in the plane and component aspects from the position of three components: technological, innovative, educational. The assessment of each component is based on three interrelated planes: formation, development and utilization.

Results. The tendency to decrease the scientific potential of the Magadan Oblast in all three components both in absolute terms and in comparison with the indicators of the Far Eastern Federal District has been revealed. The greatest reduction of indicators is revealed in the sphere of scientific and technological potential.

Conclusions. There is a growing threat to the economic security of the region due to the lag of the Magadan Oblast from other regions of the Far Eastern Federal District both on the level of innovation and technological development and on the formation of scientific personnel for the needs of the regional economy. It is recommended to concentrate efforts in the sphere of development of scientific and educational potential, since it is the sphere that determines the strategic development of the region and long-term economic security.
The role of leading financial institutions in the realization of the ESG agenda
Authors: Strijov S. A. , Abramovich S. Yu.
Published: November 2023

Aim. To identify trends and directions of development of ESG-agenda of the Russian banking sector in the new geopolitical environment.

Objectives. To analyze the reaction of the Russian banking sector to the promotion of ESGagenda by the West in the pre-sanctions period and the change of priorities after the introduction of large-scale financial and technological sanctions for Russia; to determine the required transformation of business strategies and risk management systems; to propose additional measures of support from the state to increase the priority of sovereign technologies in the implementation of ESG-transformation and the development of a competitive national system of standards.

Methods. The authors applied a mixed method of analysis, combining qualitative and quantitative data, to form the empirical base of the study. Content analysis and empirical methods were used to analyze qualitative data. In turn, quantitative data were processed using statistical and logical tools.

Results. The conducted research allowed to confirm the effectiveness of ESG-tool in the realization of the concept of sustainable development. It was determined that the significant driving force of ESG-transformation today is mainly large banks. However, the potential of ESG-transformation on the part of banks may be exhausted, and the practical part of fulfillment of plans reflected in their ESG-policies requires additional incentives from the state.

Conclusions. Based on the results of the conducted research, it becomes clear that it is necessary to form a competitive Russian sovereign ESG-model, which should include a national regulatory framework, technological standards, and domestic platform IT management systems. Strengthening the work in this direction’ financial market participants are most able to influence the introduction of innovations in the sphere of tools for achieving sustainable development goals (SDGs) and national projects, to take into account national interests in view of ESG-agenda realization, to ensure their development and financing.
Pengaruh Pengawasan dan Motivasi Terhadap Kinerja Karyawan Pada PT Promexx Stationery Kota Palembang
Authors: Wijaya Richo , Halin Hamid , Wulandari Try
Published: November 2023

Faktor yang dapat mempengaruhi kinerja karyawan adalah pengawasan dan motivasi. Penelitian ini bertujuan untuk menguji pengaruh pengawasan dan motivasi terhadap kinerja karyawan. Penelitian ini diawali dengan survei kepada 60 karyawan sebagai sampel responden di PT Promexx Stationery Kota Palembang. Jenis data dalam penelitian ini menggunakan data primer yang diperoleh langsung oleh responden dengan menggunakan metode kuantitatif. Teknik pengumpulan data dilakukan dengan menyebarkan kuesioner kepada 60 responden dan melakukan wawancara. Berdasarkan hasil pengujian bahwa pengawasan dan motivasi secara parsial berpengaruh positif terhadap kinerja karyawan (0,001 < 0,05). Dan pengawasan dan motivasi secara simultan (sig F 0,001 < 0,05) berpengaruh positif terhadap kinerja karyawan. Sehingga dapat dibuktikan bahwa pengawasan dan motivasi kerja merupakan aspek yang sangat penting dalam mempengaruhi kinerja karyawan PT Promexx Stationery Palembang.
Pengaruh Keterikatan Pegawai, Komitmen Organisasi, dan Motivasi Kerja Terhadap Kinerja Pegawai PT. PLN (Persero) Palembang
Authors: Al Farisi Salman , Halin Hamid , Ulum Bahrul
Published: November 2023

Faktor yang mempengaruhi kinerja karyawan adalah komitmen organisasi, dan motivasi kerja. Penelitian ini bertujuan untuk mengetahui Pengaruh Keterikatan Pegawai, Komitmen Organisasi dan Motivasi Kerja terhadap Kinerja Pegawai pada PT. PLN (Persero) UP3 Palembang. Penelitian ini dilakukan dengan survey kepada 97 responden karyawan sebagai sampel di PT. PLN (Persero) UP3 Palembang. Jenis data dalam penelitian ini menggunakan data primer yang diperoleh langsung dari responden dengan menggunakan metode kuantitatif. Teknik pengumpulan data dilakukan dengan menyebarkan kuesioner kepada 97 responden melalui googleform. Berdasarkan hasil pengujian uji t bahwa Nilai Signifikan Keterikatan pegawai (X1) sebesar 0,674 > 0,05 dan t-hitung pada tabel 0,421 < t-tabel 1,661. maka, X1 tidak berpengaruh terhadap Kinerja Pegawai (Y). Nilai Signifikan Komitmen Pegawai (X2) sebesar 0,004 < 0,05 dan t-hitung pada tabel 2.964 < t-tabel 1,661. maka, X2 berpengaruh terhadap Kinerja Pegawai (Y). Nilai Signifikan Motivasi Pegawai (X3) sebesar 0,000 < 0,05 dan t-hitung pada tabel 4.372 < t-tabel 1,661. maka, X3 berpengaruh terhadap Kinerja Pegawai (Y). Berdasarkan Koefisien determinasi Keterikatan Pegawai, Komitmen Organisasi dan Motivasi Kerja memberikan pengaruh yang signifikan terhadap Kinerja Pegawai PT PLN (PESERO) UP3 Palembang. Serta Berdasarkan uji f, f-hitung (44.317) > t-tabel (3,093). Terdapat pengaruh variabel Keterikatan Pegawai (X1), Komitmen Organisasi (X2) dan Motivasi Kerja (X3) terhadap Variabel Kinerja Pegawai (Y).
Assessment of Strategy Implementation on Organizational Performance: A Case of Kenya Power and Lighting Company
Authors: Wangiri Caroline , Yatich Henry
Published: November 2023

This study assessed the barriers to strategy implementation on the performance of Kenya Power and Lighting Company Limited (KPLC) in Nairobi County, Kenya. It had four objectives: to establish the influence of strategic leadership, staff competencies, strategic planning, and organizational structure on performance of KPLC. The study used a descriptive research design. The study was conducted at Kenya Power and Lighting Company.  The managerial employees of Kenya power and Lighting Company Limited constituted the study's population. At Kenya Power and Lighting Company Limited, there were 180 management staff members who made up the sample frame for the research. Formulae developed by Yamane (1967) were used to determine how representative the survey's sample was of the whole population. Sample size was 124 respondents. A questionnaire was used to collect data from respondents who are randomly selected from different departments or units of KPLC. The data was analyzed using SPSS version 21 and presented using descriptive statistics. Descriptive and inferential statistics were obtained. The study found that all the four objectives revealed a positive influence on performance of KPLC. In conclusion, strategic leadership, staff competencies, strategic planning, and organizational structure play crucial roles in shaping KPLC's performance by providing direction, motivation, innovation, alignment, coordination, adaptation, evaluation, communication, decision-making, and leadership. Finally, the study recommended that KPLC should continue to foster a culture of strategy implementation that can enhance its performance in a dynamic environment. Moreover, KPLC should also address any potential barriers or challenges in the strategy implementation process or outcomes that may affect its performance or competitiveness
Analysis of spatio-temporal variability of Pacific water distribution in the Sea of Okhotsk based on Lagrangian approach
Authors: Kivva K. K. , Budyansky M. V. , Uleysky M. Y. , Prants S. V.
Published: November 2023

The aim of this work is characteristic of spatio-temporal variability of Pacific water distribution in the Sea of Okhotsk based on Lagrangian approach and spatial analysis.

Materials and methods. The study is based on geostrophic current data product from satellite altimetry. The dataset has resolution of 0,25° × 0,25° × 1 day. This data is used for calculation of approximately 100000 water parcels trajectories during 400 days back in time for every day from 31st of January 1997 to 17th of April 2022. For each date in this interval, those parcels which intersected the conditional Kuril transect were determined, as well as region and date of transect intersection. Those two parameters were used in cluster analysis with DBSCAN method in order to distinguish individual Pacific intrusions. Position, shape, and size of each intrusion were investigated.

Results allowed to suggest two types of indexes describing distribution of Pacific-origin water in the Sea of Okhotsk. First, centroid of particles of Pacific origin with residence time between 1 and 6 months is calculated. Variability of centroid position showed northward displacement of Pacific waters in spring-summer and south[1]ward displacement in autumn-winter. Eastward displacement towards Kamchatka coast usually occurs during winters and opposite westward displacement is usual for summers. In 1998, 2003, 2010, 2013, 2017, and 2019 waters of Pacific origin had the most northern location. Second type of indexes is based on location and shape characteristics of Pacific water intrusions. The fractal dimensionality and convexity measure of intrusions are rapidly decreasing after the intrusion reaches its maximum area. Centroids of the most prominent intrusions follow the path along 152–154 °E. Both types of indices showed intensification of Pacific inflow since 2010.

Practical value. The time-series of resulted indexes are suggested to be implemented in integrated ecosystem assessments of the eastern Sea of Okhotsk.
Studies of microplastic content in water and commercial fish: from scientific research to large-scale monitoring
Authors: Kolonchin K. V. , Pedchenko A. P. , Belyaev V. A.
Published: November 2023

Purpose. The article presents proposals for the development of studies of microplastic pollution of waters and biological resources in the Russian fishery areas.

 Materials and methods. The materials of VNIRO on the quantitative assessment of the MPs content in the Arctic Seas in August-October 2019–2022 and modern research on this problem are summarized. MPs samples were collected on the surface of the seas with a Manta-trawl 335 and processed according to a single method.

 Results. The conducted studies pick up knowledge gaps regarding the real level of marine MPs pollution of the Arctic region.

Novelty. No large-scale localization of MPs was detected in the observation areas, the level of plastic pollution on the surface of the Russian Arctic seas was lower compared to other areas of the World Ocean. We point out the relevance of the assumption that a significant part of MPs fragments and fibers are transported by Atlantic and Pacific currents to the Arctic basin. A sample survey of fish in commercial catches for MPs contamination confirmed the presence of its fragments and fibers in the digestive tract of some individuals (pink salmon, greenlings, herring, sea bass) caught in the North Pacific seas in 2019, 2021 and 2022.

Practical significance. The global increase in MPs content in the Northern hemisphere seas, exacerbated by climate change, requires a transition from exploratory scientific observations to regular multidisciplinary study of plastic pollution of biotopes of ecosystems of the Arctic, North Pacific and Atlantic seas. The key points and tasks of monitoring microplastic pollution of waters and biological resources in the Russian fishing areas provide for objective and comparable assessments based on the use of unified methods of collection and processing of samples, as well as an ecosystem approach to prevent environmental risks and ensure food safety.
Russian Pollock market: current state and ways of its development
Authors: Semin A. N. , Truba A. S.
Published: November 2023

The purpose of the work: to determine the main factors hindering the harmonious development of the domestic pollock market, and taking into account the assessment of the potential, the price of fish products, the demand for pollock, the results of monitoring preferences and other factors, to develop scientifically based proposals for its further development.

Materials and methods: official data published by the Federal State Statistics Service, the Association of pollock miners (ADM) were used in the work. Diagnostics and monitoring of results were carried out, determinant and systematic approaches were applied. In some cases, content analysis was used.

The results of the study consist in identifying factors of a motivational and demotivation nature that affect pollock market participants. Proposals have been developed to eliminate and mitigate the impact of extreme factors on the market. It has been established that the competitive advantages of the pollock market in Russia can be formed not only through access to cheap sources of raw materials, but also through the improvement of organization and management along the entire chain of movement of products from the place of fish catch to its consumption.

The practical significance lies in the possibility of using the results of the study in the development of economic, financial, technical and technological measures, methods and mechanisms aimed at solving the problem of increasing the level of per capita consumption of fish products, indicated in the strategy for the development of the fishery complex until 2030.
Features of the distribution of hydrological, chemical and biological characteristics in the waters of the Central-East Atlantic in the autumn of 2022 (cruise 63 of the R/V «Akademik Ioffe»)
Authors: Artamonova K. V. , Krasheninnikova S. В. , Priymak A. S. , Babich S. A. , Demidov A. N.
Published: November 2023

The goal of the work: to determine the water structure in the Central part of East Atlantic and to identify the features of the distribution of hydrological, chemical and biological characteristics of the upper layer in the autumn period

Materials and methods: the data presented in the work were obtained on the 63rd cruise of the R/V «Akademik Ioffe» (September 29, 2022–December 8, 2022). During the expedition, hydrological and chemical (temperature, salinity, pH, dissolved oxygen, phosphates, nitrites, nitrates and silicates) characteristics were measured from the surface to the bottom, as well as biological (number, biomass and species diversity of phytoplankton), taken with chemical samples on depths of 0, 10, 20 and 50 m. Chemical analysis was carried out in the ship’s laboratory, according to certified methods for sea and fresh waters. Phytoplankton samples were thickenedusing a reverse filtration funnel through track (nuclear) membranes and fixed with Lugol’s solution to a final concentration of 5%. To study the species diversity, abundance and biomass of plankton microalgae, samples were processed by direct microscopy of algae in a living and thickened drop (V = 0.01 ml), as well as in a counting chamber (V = 0.5 ml) using an Olympus CX43 light microscope (magnification 10×20, 10×40). Identification of taxonomic groups and species composition of microalgae, calculations of the abundance and biomass of phytoplankton, as well as the Sörensen-Czekanowski floristic similarity coefficient according to the adoption of the methods of the « IBSS RAS» were carried out.

The practical significance of the research: assessment of the production stock in a poorly studied region of the Central Eastern Caucasus, identification of mechanisms for influencing production processes, assessment of the variability of the water structure against the background of climate change.
Sex steroid hormones and steroid secretory cells in the gonads of cyclostomes and fish
Authors: Zelennikov О. V. , Mosyagina M. V.
Published: November 2023

. The purpose of this work is to generalize data on the content of sex steroid hormones in cyclostomes and fish  in connection with the different state of the gonads, as well as on the localization and ultrastructural organization of steroid secretory cells (SCs).

 Method used: generalization of literature data.

  Novelty: for the first time, data on the development of SC in the gonads of juvenile fish are presented on the  scale of a literature review; changes in their localization and functional activity are shown.

 Results: Most of the data on the steroidogenic function of the gonads in fish were obtained in connection with  the study of sex differentiation (inversion) and sexual maturation (spawning). The issues of the synthesis of  sex steroid hormones and their molecular structure, blood levels in various states of the gonads, as well as the  localization and ultrastructural organization of SCs are considered. It has been noted that SCs appear in the  gonads long before sex differentiation and can be present among stromal, granulosa, and theca cells. In cyclostomes and fish — juvenile protogynous hermaphrodites in the gonads of genetic males, SCs do not appear in  the membranes around the oocytes of the previtellogenesis period, which determines their deficiency of estrogen hormones and, as a result, sex inversion. With induced sex reversal, the development of the steroidogenic  function of the gonads proceeds in the opposite direction to its natural development: in males, oocytes appear  and steroid activity shifts from the stroma of the gonads into granulosa and theca; in females, on the contrary,  secretory activity in the follicular membranes decreases and increases in the stroma of the gonads.  

Practical significance: the results of the analysis will give insight into the nature of sex steroid hormones,  their dynamics in the blood, and their role in the implementation of various processes of gonadogenesis and  gametogenesis before their practical use in fish farms.
Abundance and distribution of the Caspian seals on ice in the Russian part of the Northern Caspian in February — March 2023
Authors: Sidorov L. K. , Bizikov V. A. , Rozhnov V. V. , Shipulin S. V. , Kuznetsov V. V. , Belokobylsky I. F. , Myagkiy N. A. , Solovyeva M. A. , Glazov D. M. , Nazarenko Ye. A.
Published: November 2023

The aim of this research was to assess the current abundance of the Caspian seal population on ice in the Russian part of the North Caspian using instrumental methods of aerial survey in the infrared and optical ranges using a manned aircraft and UAV.

The main method of the research was a multispectral aerial survey, the essence of which is to survey seal haulouts synchronously in the infrared and optical ranges. In winter, 90% of all mature individuals gather on the ice substrate of the Northern Caspian for reproduction, lactation and mating and spend a significant part of their time outside the water, which greatly facilitates their detection and counting. The aerial survey was carried out in parallel from two types of aircraft — the La‑8 manned amphibious aircraft and unmanned aerial vehicles equipped with high-resolution cameras in optical and infrared modes, which ensure reliable registration of seals on ice.

Novelty: the advantage of joint use of a manned aircraft and a UAV equipped with special photo and infrared equipment is noted.

As a result of the research, the flights were carried out from February 20 to March 5, 2023 in the daytime in good visibility conditions at an altitude of 200 to 300 m. amounted to 19704 individuals, including 4062 puppies. The animals were located in the southeastern part of the ice cover near the air demarcation line between the Russian Federation and the Republic of Kazakhstan on the ice edge. An increase in the number of seals was recorded due to migrating individuals from Kazakhstan. Breeding of the Caspian seal in winter 2022/2023 proceeded in a satisfactory manner. During the flight, it was found that there were no fresh releases of seals on the coast of Dagestan. Separate old carcasses, partially torn to pieces, were registered only on the shores of the Agrakhan Peninsula.

Practical value: the obtained data are needed to assess the current abundance of the Caspian seal population in the Caspian Sea.
Процесс стерилизации лекарственного растительного сырья Origanum vulgare L. при помощи управляемого инфракрасного излучения
Authors: Худоногов Игорь Анатольевич , Худоногова Елена Геннадьевна
Published: November 2023

Введение. Большое значение в фармацевтическом производстве и в сельском хозяйстве имеет чистота растительного сырья. Содержание микробной чистоты сырья необходимо довести до уровня, установленного ГФ и научно-технической документацией. Обработка сырья растительного происхождения с использованием инфракрасного облучения (ИК-облучения) обладает рядом преимуществ: высокой тепловой эффективностью, быстрой скоростью обработки, эффективностью обеззараживания обсемененного материала.

Цель - определение оптимального режима ИК-облучения лекарственного сырья душицы обыкновенной до требуемых стандартов, удовлетворяющей микробиологической чистоте.

Объект исследования – сырье душицы обыкновенной, загрязненное аэробными бактериями (более 107 - при норме не более 107), дрожжевыми и плесневыми грибами (более 105 - при норме не более 104), а также другими кишечными бактериями (104 при норме 102).

Материалы и методы. Исследования оптимальных режимов термообработки обсемененного сырья душицы проводили на ИК-установке по 4 параметрам: времени обработки, интенсивности ИК-облучения, температуры обработки, толщины слоя растительного сырья. Образцы сырья были подвергнуты микробиологическим и фитохимическим анализам в “Центре сертификации контроля качества лекарственных средств комитета по фармацевтической деятельности и производству лекарств администрации Иркутской области и лаборатории Иркутского государственного центра Госсанэпиднадзора”.

Результаты. При термообработке сырья душицы температура на поверхности сырья должна находиться в пределах 65-75º при экспозиции 15-45 секунд, интенсивности ИК-облучения 7,5 кВт/м2. Нагрев сырья до температуры 85º и выше вызывает значительное снижение содержания эфирных масел (на 76% от исходного). Оптимальная температура нагрева - 65º, при которой содержание эфирных масел соответствует требованиям, предъявляемым к качеству сырья. При плотности мощности 2,5 и 5 кВт/м2 стерилизация сырья не происходит.

Выводы. Предлагаемый энергосберегающий метод стерилизации позволяет снизить уровень микробной обсемененности сырья душицы обыкновенной до норм, установленных Государственной фармакопеей и санитарно-эпидемиологическим надзором и получить сырье повышенного качества с оптимальным составом эфирных масел (от 0,25% в контроле до 0,13% после обработки).
Создание функциональных кисломолочных продуктов на основе новых штаммов молочнокислых бактерий с высокими органолептическими показателями
Authors: Каночкина Мария Сергеевна , Шипарева Мария Герасимовна , Билялова Анастасия Сергеевна , Смирнов Николай Борисович
Published: November 2023

Произведен скрининг штаммов молочнокислых бактерий (далее – МКБ), идентифицированных с применением метода MALDI–TOF MS, пригодных для производства пищевых продуктов, отобраны высокопродуктивные штаммы. На базе отобранных штаммов созданы образцы напитка, обладающие функциональными свойствами. Количество колониеобразующих единиц пробиотического микроорганизма в приготовленных напитках составило от 2,8×1012 до 1,5×1013 КОЕ/см3, что является высокими значениями и способствует увеличению профилактического воздействия на макроорганизм. Проведена органолептическая оценка образцов на соответствие требованям ТР ТС 033/2013.
Автоматизация управления процессами выращивания культур в тепличных комплексах вертикального типа
Authors: Рябинов Артём Валерьевич , Виноградов Михаил Сергеевич , Левоневский Дмитрий Константинович , Лоскутов Святослав Игоревич
Published: November 2023

Введение. Современные методы и средства автоматизации технологических процессов в сельском хозяйстве и, в частности, в тепличных комплексах, являются предметом исследования многих научных коллективов, но многие решения носят частичный характер, т.е. обычно охватывают отдельные технологические параметры, либо позволяют осуществлять мониторинг, но не контролировать процессы. Нередко решения рассчитаны в значительной мере на использование в ручном режиме или не предусматривают адаптивное управление параметрами теплицы. Такие решения не в полной мере удовлетворяют требованиям практики.

Цель. Необходимо повысить уровень автоматизации технологических процессов в вертикальных фермах за счет разработки методов, моделей и архитектуры адаптивного управления этими процессами.

Материалы и методы. В данной работе предлагается трехуровневая модульная архитектура АСУ ТП современного тепличного комплекса, использующая в качестве интерфейса CAN-шину и характеризующаяся масштабируемостью, модульностью и возможностью охвата всех технологических процессов автоматического выращивания культур в теплицах. Нижний уровень содержит датчики и исполнительные механизмы. Средний уровень содержит модули ввода и вывода, сбора данных, блоки управления. Верхний уровень представляет собой SCADA-систему, персональный компьютер, на котором развернут сервер, принимающий и агрегирующий информацию от модулей логики и сбора данных и предоставляющий пользователю графический интерфейс для контроля и управления процессом.

Результаты. За счет использования функциональных модулей предлагаемая архитектура обеспечивает возможность мониторинга, контроля и управления всеми технологическими параметрами, такими как: микроклимат теплицы, полив, освещение, экранирование, вентиляция. Моделирование показывает способность системы на основе такой архитектуры соответствовать временным критериям, установленным для технологических процессов и взаимодействия с пользователями.
Сравнительная оценка спектральных люминесцентных характеристик молока и молочных продуктов
Authors: Беляков Михаил Владимирович , Никитин Евгений Александрович
Published: November 2023

Введение. Разработка аналитических методов контроля молока и молочных продуктов имеет важное значение для их хранения и переработки. Спектральный фотолюминесцентный метод контроля отличается высокой чувствительностью и селективностью, не требует химикатов в качестве расходного материала.

Цель. Исследование спектральных характеристик фотолюминесценции молока и молочных продуктов для последующего создания методик их контроля.

Материалы и методы. Измеряли спектральные люминесцентные характеристики и рассчитывали параметры молока, сметаны, творога и сливочного масла (Агрофирма «Катынь», Смоленская область) в диапазоне 200-600нм по ранее разработанной методике с использованием дифракционного спектрофлуориметра «Флюорат-02-Панорама».

Результаты. Диапазон наибольшего возбуждения исследованных продуктов составил 220-340нм. Основные максимумы возбуждения 231, 262, 271, 288, 308 и 322нм. Для кисломолочных продуктов добавляется пик на 250нм. Спектры фотолюминесценции и интегральные параметры молока при скисании практически не меняются. При этом для коротковолнового возбуждения (262нм) как спектральные характеристики, так и интегральные потоки в два раза больше, чем для длинноволнового (442нм). Сравнивая потоки фотолюминесценции сметаны и молока видно, что при коротковолновом возбуждении для сметаны они примерно в два раза ниже, а при длинноволновом – примерно одинаковы, что согласуется со спектрами возбуждения. Для творога при всех использованных длинах волн возбуждения спектры получились качественно одинаковыми, но по интегральному потоку наилучшим является возбуждение 288нм. Предположительно, люминесценция больше при повышенном содержании белков и пониженном содержании жиров, что подтверждается исследованием фотолюминесценции сливочного масла.

Выводы. Для возбуждения молока и кисломолочных продуктов наиболее целесообразным является использование длин волн возбуждения 262 нм (молоко), 271 нм (сметана) и 288 нм (творог). Для сливочного масла следует выбирать более длинноволновое возбуждение – 308нм. При этом фотолюминесцентное излучение следует измерять в диапазонах 290-400нм для молока, сметаны и творога, а для масла – в диапазоне 340-450нм. Полученные результаты могут быть применены для создания методик экспрессного контроля переработки и хранения молока и молочных продуктов.
Влияние предварительной обработки импульсным электрическим полем на процесс сушки: обзор предметного поля
Authors: Бурак Леонид Чеславович , Сапач Александр Николаевич
Published: November 2023

Введение: Основное влияние на качество сушеных продуктов, включая физико-химические, микробиологические, органолептические показатели и пищевую ценность, оказывает используемый технологический процесс сушки. Цель данной статьи —критический обзор результатов опубликованных научных исследований применения импульсного электрического поля, с целью обработки пищевых продуктов перед процессом сушки.

Материалы и методы исследования: Поиск зарубежной научной литературы на английском языке по вопросам влияния предварительной обработки сырья импульсным электрическим полем на процесс сушки и качество готовой сушеной продукции проводили в библиографических базах «Scopus», «Web of Science», а также других источниках.  В качестве временных рамок для обзора научных публикаций был принят период 2010–2023 гг. е статьи изучали только при отсутствии новых публикаций по теме исследования. При выполнении работы использованы научные методы поиск и скрининг научной литературы, извлечение данных, их анализ , систематизации и обобщения. При отборе публикаций для обзора приоритет отдавали высокоцитируемым источникам. Результаты анализа были представлены в виде таблиц и диаграмм для визуализации данных. Для обзора предметного поля проведенного исследования использовали алгоритм в соответствии с протоколом и составили схему проведения исследования. Материалами для исследования послужили 126 статей.

Результаты: Сушка с применением предварительной обработки импульсным электрическим полем способствует сохранению физико-химических свойств высушенных продуктов, их цвета и содержащихся биологически активных соединений, а также улучшает кинетику сушки. В отличие от традиционных технологий, сушка с использованием импульсного электрического поля обеспечивает селективную дезинтеграцию клеток, не оказывая при этом отрицательного воздействия на качество продукта. Предварительная обработка импульсным электрическим полем вызывает инактивацию микроорганизмов и окислительных ферментов, что способствует максимальному сохранению качественных показателей готового продукта после сушки. Плоды и овощи, предварительно обработанные импульсным электрическим, обладают улучшенными качественными показателями после сушки по сравнению с теми, которые не подвергались обработке. Готовые продукты, обработанные импульсным электрическим полем перед сушкой, имели более насыщенный цвет и более высокую антиоксидантную активность, а также время процесса сушки таких продуктов значительно короче. 

Выводы: Предварительная обработка импульсным электрическим полем перед сушкой способствует сокращению времени сушки, снижению энергоемкости и сохранению биологически активных соединений в готовом продукте. Материалы данной статьи могут быть использованы при проведении дальнейших научных исследований и промышленного использования данной технологии обработки.
Яблочные выжимки как источник функциональных пищевых ингредиентов: обзор предметного поля
Authors: Коденцова Вера Митрофановна , Рисник Дмитрий Владимирович , Серба Елена Михайловна , Абрамова Ирина Михайловна , Туршатов Михаил Владимирович , Соловьев Александр Олегович
Published: November 2023

Введение. Яблочные выжимки представляют собой побочный продукт, образующийся при производстве соков. Масса яблочных выжимок в зависимости от способа производства сока и используемой аппаратуры может составлять от 28 до 60% от массы исходного сырья. В данной обзорной статье представлен анализ возможности использования яблочных выжимок в качестве функционального компонента пищевых продуктов.

Методика. Обзор существующей по проблеме литературы за последние годы осуществляли по базам данных РИНЦ, Pubmed и в системах Google Scholar, ReserchGate.

Результаты. По своей сути яблочные выжимки представляют собой концентрат пищевых волокон, содержащий значительное количество природных антиоксидантов (фенольные соединения), связанных с углеводной матрицей. В отношении организма человека яблочные выжимки сочетают в себе свойства двух типов веществ – пищевых волокон и антиоксидантов. В технологическом отношении яблочные выжимки являются функциональным ингредиентом, обладающим влаго- и маслоудерживающей способностью, улучшают текстуру, повышают антиоксидантную активность продукта.

Выводы. Введение яблочных выжимок в рецептуру обеспечивает не только улучшение технологических свойств хлеба и мучных кондитерских изделий (кексы, печенье, бисквиты, крекеры), молочных ферментированных (йогурты), мясных (сосиски, колбасы, мясорубленые изделия), экструдированных и других продуктов, вызывая некоторое потемнение конечного продукта, но и повышает пищевую ценность за счет увеличения содержания пищевых волокон и антиоксидантных свойств продукта. Включение яблочных выжимок в рацион крыс с высоким содержанием жира и сахарозы приводит к улучшению липидного профиля сыворотки крови, препятствует повышению массы тела. Яблочная выжимка является функциональным, экономичным и полезным ингредиентом в рецептуре пищевых продуктов.
Reden halten – aber wie?
Authors: Lehmann Günter
Published: November 2023

Reden halten ist längst nicht mehr das Privileg einiger weniger Repräsentant:innen. Studierende sowie Fach- und Führungskräfte kommen heute vielfach in die Situation, eine Rede halten zu müssen. Für die Ungeübten bleibt dann meistens wenig Zeit für eine theoretische Einarbeitung, eine praktische Anleitung ist gefragt. Das Buch vermittelt Handlungsorientierungen für alle gängigen Redetypen.
utb+: Zusätzlich zum Buch erhalten Leser:innen als digitales Zusatzmaterial Check- und Merklisten, Argumentationshilfen sowie Zusammenfassungen, die beim Lernen helfen und beim Aufbau der Rede unterstützen.
Faktor – Faktor Yang Mempengaruhi Pasien Post Laringectomy Terhadap Kesediaan Bergabung Dalam Perkumpulan Wicara Esofagus Indonesia
Authors: Waspada Waspada , Mansyur MS Muchtaruddin , Paramita Pradnya
Published: November 2023

Penelitian ini mengkaji faktor-faktor yang memengaruhi kesediaan pasien pasca laringectomy untuk bergabung dalam Perkumpulan Wicara Esofagus Indonesia. Metode penelitian ini adalah kuantitatif dengan desain cross-sectional. Hasil penelitian menunjukkan bahwa sebagian besar pasien (65,4%) tidak bergabung dengan PWEI. Faktor-faktor yang berpengaruh signifikan terhadap keterlibatan pasien dalam PWEI adalah terapi wicara dan peran PWEI. Implikasi penelitian ini adalah perlunya perluasan cakupan PWEI untuk menarik lebih banyak pasien pasca laringectomy, serta pentingnya integrasi data dengan fasilitas kesehatan untuk memudahkan pemantauan dan evaluasi pasien.
A síndrome de ASIA e o explante de próteses de silicone mamário
Authors: Villar Isabela De Souza , Veiga Jamile Chahoud , Coelho Bárbara Gonçalves , Abreu Isabela Valinho , Gava Isabella Bizareli , Rodrigues Virginia Dos Santos , Dias Vinícius Evangelista
Published: November 2023

Objetivo: O presente estudo teve como objetivo compilar as atuais evidências da relação dos implantes mamários com o desenvolvimento da síndrome de ASIA - síndrome autoimune induzida por adjuvantes. Por ser uma cirurgia plástica comumente realizada no Brasil e no mundo, é importante estudar sobre as possíveis complicações e consequências da mamoplastia de aumento por implante de próteses de silicone, sendo em alguns casos necessário realizar o explante. Metodologia: Foram avaliados 16 artigos durante o período de setembro e outubro de 2023 para produzir a revisão bibliográfica em questão, sendo considerados aqueles que direcionaram o estudo para a reação de autoimunidade e inflamação decorrentes do silicone bleeding em pacientes que buscaram atendimento médico após certo tempo de cirurgia com queixas de sinais locais nas mamas e sintomas sistêmicos como mialgia e artralgia; foram excluídos os artigos que abordaram o desenvolvimento de neoplasias após os implantes de silicone. Resultados e Discussão: Os resultados obtidos com a pesquisa foram que apesar das recentes evidências apontarem para uma correlação entre o aparecimento de sintomas sistêmicos de doença autoimune em alguns pacientes após a cirurgia de colocação de implantes de silicones, não há de fato uma comprovação validada pelo meio acadêmico da síndrome de ASIA, porém há diversos sintomas que podem surgir, em indivíduos com fatores de risco, que apontam para uma síndrome inflamatória e imunomediada em decorrência dos implantes mamários de silicone. Conclusão: Sabe-se que a cirurgia plástica de colocação de próteses de silicone nas mamas é muito prevalente no mundo, por isso é necessário ampliar a discussão e estudos acerca da síndrome de ASIA. Ademais, é importante estar a par para as abordagens cirúrgicas de explante, caso necessário e requerido pelos pacientes.
ESTUDO COMPARATIVO DE BIOMATERIAIS TIPO XENOENXERTO E ENXERTO ALOPLÁSTICO PARA CIRURGIA RECONSTRUTIVA ALVEOLAR COM TÉCNICA DE SINUS LIFT COM JANELA LATERAL
Authors: Ferreira Antônio Fabrício Alves , Brito Sávio José da Silva , Moura Diogo Henrique Juliano Pinto de , Guimarães Samara de Freitas , Moura Thales Filipe Barbosa de , Moura Maria Luiza Farias Gadelha de , Forte Anderson Gomes , Seixas Deborah Rocha , Lima Mabel Martins , Junior Gerson Pereira de Araújo
Published: November 2023

Os materiais que podemos utilizar como material de enxerto podem ter origens diversas, o que por sua vez condiciona as suas diferentes propriedades e comportamentos. Dependendo da sua capacidade de interagir com o osso circundante, podem ser classificados como materiais bioinertes ou bioativos. Os materiais bioativos são capazes de estimular a formação de tecido ósseo, unindo-se diretamente ao osso, formando assim uma interface forte e única entre osso e biomaterial. O material de enxerto, por outro lado, deve ser biocompatível e reabsorvido para ser integrado ao osso neoformado, que é estruturalmente semelhante ao osso, osteocondutor e, se possível, também osteoindutor e osteogênico. Quando atuamos no processo de regeneração óssea devemos também levar em consideração a sua estrutura.
PERFIL EPIDEMIOLÓGICO DA SÍFILIS GESTACIONAL NO NORTE DO BRASIL
Authors: Itapary Pedro Gabriel Araujo Pereira , Ribeiro de Assunção Alfredo Filho , De Brito Fernandes Maria Carolina , Leite Pietra Marçal Domingues , Castro Juliana Braga Rodrigues De
Published: November 2023

Este artigo tem por objetivo caracterizar o perfil epidemiológico da sífilis em gestantes na região norte do Brasil entre 2011 e 2021. Realizou-se um estudo epidemiológico ecológico retrospectivo, quantitativo e descritivo por dados coletados a partir do Sistema de Informação de Agravos de Notificação (SINAN), na plataforma do Banco de Dados Digitais do SUS (DATASUS). Observou-se uma maior prevalência da sífilis em gestantes com uma faixa etária entre 20 e 39 anos e com ensino fundamental incompleto.