bluuebunny/crossref_metadata_2025 huggingface dataset:
Fecal Calprotectin and the Complications of IgA-mediated Vasculitis: A Cohort Study
Authors: Asna Ashari Kosar , Alimadadi Hosein , Sadeghi Payman , Ziaee Vahid
Published: June 2024

Background: Immunoglobulin A (IgA)-mediated vasculitis, previously known as Henoch-Schönlein Purpura (HSP), is the most common vasculitis in children. It affects the skin, joints, gastrointestinal (GI) system, and kidneys. Calprotectin is a calcium-binding protein mainly found in neutrophils and macrophages, and its levels increase in settings of inflammation. Objectives: We conducted a study to investigate the role of calprotectin in prediction of HSP complications. Methods: In this cohort study, patients diagnosed with HSP by EULAR/PRINTO/PRES criteria and admitted to two referral children’s hospitals in Tehran, Iran, were enrolled. Fecal calprotectin levels were checked at the beginning of the presentation, and the patients were followed for GI and renal manifestations. Results: Out of the 100 patients who began to participate, 47 were eventually enrolled (25% girls). The age range was 2 to 18 years, with a mean of 6.5 ± 2.9 years. Hematuria was found in 21% and proteinuria in 17%. The Mann-Whitney test found an association between calprotectin and blood in stool (P = 0.03). No association was found between calprotectin and abdominal pain, sonography findings, hematuria, or proteinuria. The Pearson correlation test found a positive correlation between calprotectin level and leukocyte count (P = 0.003), neutrophil count (P = 0.002), and CRP (P = 0.03). Conclusions: Positive blood in stool was associated with fecal calprotectin levels in HSP, but hematuria and proteinuria were not. Considering the high cost of the calprotectin test, monthly follow-up with urine analysis appears to be a more logical approach. Neutrophil count and CRP were found to correlate with calprotectin levels, highlighting the nature of calprotectin as an acute inflammatory marker elevated during the acute phase of HSP disease.
Biomechanical Parameters for Rigidity Assessment in Parkinson's Disease: A Scoping Review
Authors: Asghari Samin , Azghani Mahmood Reza , Rahimi Fariborz
Published: June 2024

Context: Rigidity is a cardinal motor symptom in Parkinson's disease (PD), and evaluating these symptoms remains a significant challenge for researchers and neurologists. This scoping review utilizes a methodology to extract, categorize, and compare biomechanical parameters (MPs) for rigidity assessment from studies spanning the years 1980 to 2023. Evidence Acquisition: Electronic databases, including Google Scholar, ScienceDirect, PubMed, Springer, and Civilica, were systematically searched to identify research on rigidity assessment in PD utilizing various biomechanical parameters. Additionally, reference lists of identified papers were reviewed to identify additional relevant studies. A total of 53 articles met the inclusion criteria and were evaluated. Findings: Based on the results of 53 studies, viscoelastic parameters, electromyogram (EMG) signal measurements, impedance, work, and torque-angle slopes (stiffness) were identified as essential and commonly recommended parameters for rigidity evaluation in Parkinsonian patients. Furthermore, correlations between these parameters and clinical scores have been reported. Introducing biomechanical parameters capable of identifying rigidity and its severity, along with their classification, could contribute to a better understanding, modeling, and evaluation of rigidity. Conclusions: This review could be of interest to both biomechanists and neurologists, facilitating a common language for discussing aspects of rigidity in diseases such as Parkinson's.
Kajian Yuridis Putusan Mahkamah Agung No. 2239 K/PID.SUS/2012 Berkaitan dengan Tindak Pidana Perpajakan
Authors: Margareta Stefani , Tanudjaja Tanudjaja
Published: June 2024

Skandal manipulasi pajak Asian Agri melibatkan 14 perusahaan perkebunan kelapa sawit yang merugikan negara sebesar Rp 1,26 triliun. Meskipun konsep kejahatan korporasi dan pertanggungjawaban pidana korporasi tidak dikenal secara umum dalam KUHP, namun dalam UU KUP, perusahaan diakui sebagai badan hukum yang dapat dijatuhi sanksi jika melakukan misrepresentasi. Penelitian ini bertujuan untuk mengisi kekosongan literatur yang ada dengan fokus khusus pada perlindungan hukum bagi pemegang saham minoritas yang sakit jiwa dalam perseroan terbatas di Indonesia, dan diharapkan dapat memberikan kontribusi baru yang berharga dalam memperkaya pemahaman mengenai masalah ini. Studi yuridis ini berfokus pada Putusan Mahkamah Agung Nomor 2239 K/PID.SUS/2012 yang berkaitan dengan kasus pajak yang dikenal sebagai skandal manipulasi pajak pertanian Asian Agri. Penelitian ini akan menganalisis konsep pertanggungjawaban pidana korporasi dalam kasus tersebut. Kasus skandal pajak Asian Agri menunjukkan bahwa konsep pertanggungjawaban pidana korporasi dalam sistem hukum Indonesia masih memiliki ruang untuk dikembangkan, terutama terkait jenis sanksi yang dapat dijatuhkan kepada perusahaan. Pemberian sanksi yang lebih tepat bagi korporasi dapat menjadi salah satu upaya untuk meningkatkan kepatuhan pajak di Indonesia.
Heidegger’s Legacy and the Need/Use of Being
Authors: Moore Ian Alexander , Merwin Christopher D. ,   The Heidegger Circle
Published: June 2024

This article first retraces the history of Heidegger’s “The Argument against Need” and situates it in the context of extant notes from his never-completed introduction to the Gesamtausgabe titled “The Legacy of the Question of Being.” It then argues that, for the later Heidegger, Brauch (“need,” “use”) becomes another name – indeed one of the most important, albeit neglected, names – for being in its deepest sense. To appreciate Heidegger’s legacy and that of the question of being, it is crucial that we (1) critically assess the argument against Brauch qua “need” – i.e., the argument according to which the being of certain entities, such as those that predate Homo sapiens, does not depend on the human – and (2) understand the ontological sense of Brauch qua “use.” We must not only recognize that Dasein is needed for the safeguarding of truth, but also move beyond this and see being in its independent use.
ENDÜSTRİ 4.0 AKILLI HAVALİMANI YAPAY ZEKÂ UYGULAMALARININ İŞ GÖRENLER ÜZERİNE ETKİLERİNE YÖNELİK BİR ARAŞTIRMA
Authors: Özden Mehmet
Published: June 2024

Bu araştırmanın amacı 2011 yılında Almanya’da hayatımıza giren Endüstri 4.0 kavramıyla birlikte başlayan Havacılık 4.0’ın, günümüze kadar getirdiği mevcut yenilikleri ve önümüzdeki yıllarda yaşanabilecek teknolojik gelişmeleri, yönetim fonksiyonlarına olan etkilerini ortaya koymak, gelecek 10-15 yıl içerisinde yaşanacak insansızlaşmaya yönelik insan kaynağının algısını ve tepkisini, uyum sağlamak için nasıl davrandığını tespit etmek, sektörde artarak devam eden insansızlaşmanın, çalışanlar üzerine olan etkilerini ve değişimi kabul etme ve insansızlaşma ile arasındaki ilişkiyi tespit etmektir. Ortaya çıkan bulgular sayesinde sektördeki işletmelerin insan kaynağını bu değişime ve geleceğe hazırlamak, istihdam süreçlerinde kriterleri doğru belirleyerek zamanında doğru yapılandırmaları yaparak, Endüstri 4.0’a hazır beşerî sermaye birikimine katkıda bulunulabileceği düşünülmektedir. Yöntem olarak araştırma kavramsal olarak yapılmış, içerik analizi şeklinde gerçekleştirilmiştir. Araştırmaya ışık tutacak yöntem olarak kavramsal araştırma yöntemini kullanılmıştır. Veri toplama araçları olarak mülakat ve literatür tarama yöntemi kullanılmıştır.
G-20 ÜLKELERİNDE CO2 EMİSYONU, EKONOMİK BÜYÜME, KENTLEŞME VE YENİLENEBİLİR ENERJİ TÜKETİMİ İLİŞKİSİ
Authors: Akın Özdemir Neslihan
Published: June 2024

Sera gazı emisyonlarının küresel ısınma ve iklim değişikliği gibi insan sağlığı ve çevre açısından ciddi tehdit oluşturan olaylara sebebiyet vermesi ülkeleri, sera gazı emisyonlarının büyük bir bölümünü oluşturan CO2 emisyonlarının azaltmak için önlemler almaya yönlendirmiştir. Mevcut çalışmada; kişi başı CO2 emisyonu, kişi başı gayri safi yurtiçi hâsıla, kentleşme ve yenilenebilir enerji tüketimi arasındaki ilişkinin G-20 ülkeleri için 2020 verileri kullanılarak Robust Regresyon Analizi ile belirlenmesi amaçlanmıştır. Analizde CO2 emisyonu bağımlı değişken; kişi başına gayri safi yurtiçi hasıla, kentsel nüfus oranı ve yenilenebilir enerji tüketimini ise bağımsız değişken olarak kullanılmıştır. Robust regresyon analizi sonucuna göre Kanada ve Brezilya’nın aykırı gözlem olduğu tespit edilmiştir. Kişi başına gayri safi yurtiçi hasıla ile CO2 emisyonları arasındaki ilişki pozitif iken; yenilenebilir enerji tüketimi ve kentsel nüfus oranının ile CO2 emisyonları arasındaki ilişki negatif yönlü olarak tespit edilmiştir. Tüm bu bağımsız değişkenler %5 anlamlılık düzeyinde istatistiksel olarak anlamlı bulunmuştur
Strategic Analysis of Tesco's International Purchasing and Supply Chain Management: Challenges, Opportunities, and Future Directions
Authors:   The School of Economic and Management, Universiti Putra Malaysia, Malaysia, & The School of Management and Engineering, Anhui Institute of Information Technology, Wuhu, China., Li Le , Zeng Jian Hua ,   School of Chemistry and Life Science, Hubei University of Education, Wuhan 430205, China.
Published: June 2024

This review paper examines Tesco's international purchasing and supply-chain management strategies, focusing on its operations and strategic initiatives. Tesco, a prominent global retailer, faces significant challenges and opportunities in a competitive market environment. Through a SWOT analysis, Tesco's strengths in efficient logistics and expansive market reach are highlighted, alongside weaknesses such as environmental sustainability concerns and operational inefficiencies. The study also explores Tesco's value chain, emphasizing its primary activities like inbound logistics and outbound distribution, as well as supporting activities such as human resource management and technological innovations like RFID. Future challenges, including environmental sustainability and market expansion in Asia and Africa, are discussed, with recommendations provided to enhance Tesco's sustainable development and competitive position in the global retail landscape.
Faktor-Faktor yang Berhubungan dengan Kejadian Prehipertensi di Kecamatan Medan Perjuangan Tahun 2020
Authors: Herianto Manurung Canra , Syahrizal Syahrizal
Published: June 2024

Prehipertensi yang tidak terkontrol dapat menjadi awal dari hipertensi. Prevalensi prehipertensi di seluruh dunia mencapai 36,1%, sedangkan di universitas-universitas di Perhimpunan Bangsa-Bangsa Asia Tenggara (ASEAN) prevalensinya sebesar 19,6%. Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang berkaitan dengan kejadian prehipertensi pada individu berusia 25-44 tahun di Kecamatan Medan Perjuangan. Studi ini menggunakan desain analitis dengan pendekatan cross-sectional. Populasi studi terdiri dari seluruh penduduk kecamatan yang berjumlah 25.330 jiwa. Sampel terdiri dari 95 orang dewasa muda (usia 25-44 tahun) yang dipilih dengan metode purposive sampling, tidak memiliki riwayat hipertensi. Data univariat dianalisis secara deskriptif, sementara data bivariat dianalisis menggunakan uji chi-square. Proporsi prehipertensi di Kecamatan Medan Perjuangan pada tahun 2020 mencapai 57,9%. Hasil analisis menunjukkan nilai p > 0,05 untuk variabel usia, riwayat keluarga hipertensi, dan status perkawinan. Nilai odds ratio (OR) menunjukkan bahwa usia memiliki OR 11,926 (95% CI = 4,459-31,894), riwayat keluarga hipertensi memiliki OR 3,088 (95% CI = 1,241-7,684), dan status perkawinan memiliki OR 3,692 (95% CI = 1,325-10,292). Sedangkan untuk jenis kelamin, obesitas, kebiasaan merokok, dan kebiasaan minum alkohol, OR masing-masing adalah 1,934 (95% CI = 0,844-4,431), 1,953 (95% CI = 0,628-6,078), 1,579 (95% CI = 0,695-3,854), dan 2,111 (95% CI = 0,814-5,478).
BİR OSMANLI AYDINININ TAŞRAYA BAKIŞI: AHMET İHSAN’IN SEYAHAT YAZILARINDA İÇ ORYANTALİZM
Authors: Öztürk Veysel
Published: June 2024

On dokuzuncu yüzyıl sonunda Osmanlı yazın ve matbuat kültüründe seyahat
yazıları büyük bir artış gösterir. Bu yazılar asır sonundaki teknolojik gelişmelerin
Osmanlı başkenti ile Anadolu arasındaki iletişim ve ilişkileri nasıl yeniden
şekillendirdiğini izlemek için benzersiz bir imkân sağlar. Dönemin seyahat yazınının en
önemli yazarlarından birisi, Servet-i Fünûn’un imtiyaz sahibi ve müdürü Ahmet
İhsan’dır. Onun 1892-1896 arasında yeni açılan demiryolu hatları boyunca çıktığı üç
seyahatin ardından kaleme aldığı yazılarında hem maddi hem zihinsel bakımdan modernite
belirleyici bir rol oynar. Bir seyahatin gerçekçi bir kaydı olmaktan çok tıpkı otobiyografi ve
hatırat gibi bir “ben anlatısı” olarak seyahat yazını, öznel bir tecrübenin temsilidir.
Nitekim, Ahmet İhsan’ın taşraya bakışı aracısız tezahür etmez; bu bakış, seyahati
kolaylaştırarak seyahat yazınındaki artışa da neden olan demiryolu ve fotoğraf gibi
teknolojilerin aracılığıyla ve onların etkileriyle şekillenir. Yazılarında anlatmaya değer
gördüğü şeyler ve bunları anlatırken kullandığı üslup, Osmanlı idari yapısının
merkeziyetçiliğinin Osmanlı aydınının zihninde ne denli büyük bir karşılık bulduğunu
gösterir. Yerel gündelik hayatın önüne çıkan kimi manzaraları karşısında Ahmet İhsan’ın
olanı olduğu gibi anlamak yerine, onu düzene sokucu bakışı devrededir. Bu haliyle Ahmet
İhsan’ın Anadolu taşrasını alımlayış ve temsili, Oryantalist bir nitelik arz eder. Değişen
dünyanın farkında olan okumuş sınıfın bir mensubu olarak Ahmet İhsan, Anadolu’ya
modern dünyanın imkânları içerisinden bakarken her fırsatta imparatorluk taşrasını Batı
taşrası ile kıyaslar. Anadolu coğrafyası ve insanını Batı’nın Doğu algısını ödünç alarak
aktarır. Bu makale, Ahmet İhsan’ın üç seyahat yazısını İstanbul aydınının taşra ile
karşılaşması bağlamında ele alarak yazarın özellikle Oryantalist bakışının taşrayı
alımlayış ve temsilini nasıl şekillendirdiğine odaklanıyor.
ABSÜRDE BAŞKALDIRAN BİR UYUMSUZ: DELİ DUMRUL
Authors: Kahraman Berat Samet
Published: June 2024

İnsan, varlığı itibariyle sonludur. Her zaman ölüme doğru bir varlıktır. Yaşamı içinde ölüm fenomeniyle karşılaşan insan, ölümden kaçar. Öleceğini bilir ancak bunu unutarak yaşar. İnsan, “fırlatıldığı” bu dünyada seçeneksiz kılınışı karşısında, dünya ve kendisi arasında anlamlı bir ilişki kuramaz. Çalışma, insanın içine düşürüldüğü bu durumu “absürt” kavramıyla ortaya koyan Albert Camus’nun felsefi görüşünü temel almaktadır. Camus, absürt duygusuyla yaşayan insanı, “uyumsuzu” yaratır. “Duha Koca Oğlı Delü Dumrul” da absürde başkaldıran bir delidir/uyumsuzdur. İnşa ettiği köprüsü üzerinden insanlığın “ölüm” karşısındaki trajedisini öyküler. Deli Dumrul anlatısı Albert Camus’nun felsefi bir kavram haline getirdiği ve sınırlarını belirlediği “absürt felsefe” noktasında ele alınmıştır.
ERKEN CUMHURİYET DÖNEMİ HALKEVLERİNDE OYNANAN TİYATRO ESERLERİNDE İDEOLOJİK BİR SÖYLEM OLARAK ERGENEKON ANLATISI
Authors: Uysal Makbule
Published: June 2024

Kültürün en önemli unsurlarından olan anlatılar, modern zamanda ortaya çıkan ideolojilerin kullanım alanı içerisinde yerlerini almıştır. Bir kısmı halk arasında sözlü olarak yaşayan bir kısmı dönemin tarih kitaplarında yer alan efsane, destan, masal gibi anlatılar, 19. yüzyılda romantik milliyetçi ideoloji tarafından toplumun bağlayıcı bir unsuru olarak kullanılmıştır. Milliyetçi ideoloji Avrupa’daki pek çok ülkenin ulus-devlet inşa süreçlerinde kurucu ideoloji olarak yer alır. Milliyetçi ideoloji 19. yüzyılda Osmanlı İmparatorluğunda, imparatorluk içinde yer alan milletleri etkilemekle birlikte dönemin Osmanlı aydınları tarafından da kabul görmüş, ortak ve kadim bir Türk tarihi/atası düşüncesinin kaynakları olan anlatılarla ilgili çalışmalar bu dönemde başlamıştır. Bu çalışmalar, imparatorluk sonrası kurulan Türkiye Cumhuriyeti’nin kurucu ruhunu yansıtan pek çok sanat eserine sirayet etmiştir. Devletin kurucu ideolojisine uygun olmayan anlamlar dünyasının yeniden düzenlenmesi, değiştirilmesi ya da ıslah edilmesini içeren bir süreç olarak ele alınan Erken Cumhuriyet döneminde çeşitli mit anlatılarına devletin ideolojisinin halka benimsetilmesi için başvurulduğu görülmektedir. Bu çalışma, devletin ideolojik aygıtı olarak işlev gören Halkevlerinde oynanan, dönemin dil ve tarih çalışmalarına uygun olarak kurgulanmış tiyatro eserlerinde işlenen Ergenekon mitinin kendi anlamının dışına çıkarak hâkim ideolojinin anlamlar dünyasına eklemlenmesine odaklanmaktadır. Bu çalışmada Nihat Şevki’nin Ergenekon oyunu mitin doğrudan kendisini konu edinmesi, Faruk Nafiz Çamlıbel’in Akın ve İbrahim Tarık Çakmak’ın Bozkurt oyunları ise bu mite simgesel benzerlikler taşıması nedenleriyle örnek olarak seçilmiştir.
Die 63. Jahrestagung der Permanent International Altaistic Conference (PIAC), „Communality and Mutual Influence of Language and Civilization in the Altaic World“, in Ulaanbaatar (26.-28. August 2021)
Authors: Knüppel Michael
Published: June 2024

Der folgende Text enthält den Konferenzbericht der 63. Jahrestagung des PIAC in Ulaanbaatar. Die einzelnen Beiträge der Konferenz werden jeweils kurz zusammengefasst.
A Feminist Critique of Women Portrayal in NGUGI WA THIONGO’S Devil on the Cross
Authors:   Faculty of Education Kampala International University, Edith Nabasa , Earnest B Ainembabazi ,   Faculty of Education Kampala International University, Kiplagat Gideon Too ,   Faculty of Education Kampala International University, Hadijja Nantale ,   Faculty of Education Kampala International University, Tarcis Niwagaba ,   Faculty of Education Kampala International University
Published: June 2024

African American Literature demonstrates that the Black Women's Feminism Caucus acknowledged that black women faced a dual patriarchal oppression from within their own community and from white society. This paper examines how Devil on the Cross portrays a Kikuyu woman striving for liberation and transformative change in Kenyan society. Employing a feminist perspective, the researcher contends that Ngugi Wa Thiong'o illustrates the plight of women in Kenyan society, interpreting feminism within its cultural framework. Building on this foundation, the study advocates for the designation of essential services such as police protection, justice, shelters, helplines, and community support services, ensuring they receive adequate support and resources to operate during pandemics and other public emergencies affecting women and girls. It emphasizes the necessity of involving women and women's civil society organizations in policy formulation, development, and implementation to integrate their knowledge, experiences, and needs into response strategies. Furthermore, it stresses the importance of prioritizing prevention and protection against gender-based and domestic violence in national responses by collecting detailed data on the prevalence of such violence and identifying which demographics of women and girls are most vulnerable. Keywords: Domestic violence, Feminist critique, Fiction, Women emancipation, Women portrayal
Church Financial Demands and Christian Church Attendance in Kyeizooba Sub County, Bushenyi District of Uganda
Authors:   Faculty of Education Kampala International University Uganda, Shibar Arinaitwe , Baagala Gwokyalya Edith ,   Faculty of Education Kampala International University Uganda, Earnest Ainembabazi ,   Faculty of Education Kampala International University Uganda, Aja Lucy ,   Faculty of Education Kampala International University Uganda, Tumuhairwe Justine ,   Faculty of Education Kampala International University Uganda
Published: June 2024

Church financial demands has led to lack of trust among church leaders and their believers due to frequency of the financial demands from church members without accountability to the members. This has brought lack of trust among church leaders by followers hence reducing attendance of Christians in church and occasioned the creation of different churches by the members due to mistrust between each other. In the light of the above observations, the study calls for Church preachers to explicitly explain God’s word and bring their worshippers to knowledge of God. The church should start self-sustaining projects like rearing cattle, chicken and other agricultural projects so that its treasury can be increased. There is need for churches to form worship memberships’ care team that review the attendance of their worshipers. Finally, there is need for leaders of the church to constantly visit the homes of their Christian brothers, pray for them so that their investments can be blessed by God. Keywords: Christian church, Church financial demands, Membership, Religious market, Worshippers
Investigating how Road Development Enhances Agricultural Production in Bubandi Sub County of Bundibugyo District, Uganda
Authors:   Faculty of Education Kampala International University, Uganda., Shibar Arinaitwe , Deneth Turyahabwe ,   Faculty of Education Kampala International University, Uganda., Azalius Tugume ,   Faculty of Education Kampala International University, Uganda., Godiriva Atuhairwe ,   Faculty of Education Kampala International University, Uganda., Kanyesigye Stella  Teddy ,   Faculty of Education Kampala International University, Uganda.
Published: June 2024

This study investigated the intertwine between road development and agricultural production in Bubandi Sub County of Bundibugyo District, Uganda. Findings revealed that the poor road network in the district is caused by steep slopes, difficulties in compensating project affected residents, government delays in providing cash, and weather variations. This poor road network equally threatens food security. This is because road development increases the agricultural productive capacity of poor households, lowers input and transportation costs, creates a market for agricultural produce, improved regional interaction, opens up new economic areas, and facilitates the flow of goods, especially agricultural produce, from rural to urban areas. Based on this finding, the study calls for the Uganda National Roads Authority (UNRA) to build all-weather loose surface roads to connect economically beneficial areas and provinces. The government should directly incentivize and oversee farmers to grow the sub county's agriculture. This is because most farmers lack agricultural incentives to inspire and boost their output. The government should build standardised highways and extend rural electrification, to encourage post-harvest handling technologies. Finally, the government should increase infrastructure and agricultural extension budgets in rural areas. Keywords: Agricultural output, Agricultural production, Feeder roads, Road development, Standard of living.
All about citation chasing and tools that does citation chasing like Citation Gecko, Connected papers, Research Rabbit, LitMaps and more
Authors: Tay Aaron
Published: June 2024

I have been writing about what I call citation based literature mapping tools for over 5 years now, starting from Citation Gecko in 2018.
Click Chemistry; Inspired Synthesis and Antimicrobial Evaluation of 1,2,4-triazolo [4,3-a]pyridine linked 1,4-disubstituted 1,2,3-triazole Derivatives with Amide Functionalities
Authors: Parmar Rahul V. , Vadodaria Milan S. , Gajera Prashant S.
Published: June 2024

In an attempt to rationalize the search for new potential antimicrobial agents, a new series of 1,2,4-triazolo[4,3-a] pyridine linked 1,4-disubstituted 1,2,3-triazoleswith amide linkage has been synthesized by the cyclization of 1,2,4-triazolo[4,3-a]pyridine-based alkynes and 2-azido N-phenylacetamide in the presence of CuSO4 as catalyst through ??Click Chemistry" approach. The newly synthesized scaffolds have been evaluated for their antimicrobial potential using eight microbial strains such as Escherichia coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Bacillus megaterium, Staphylococcus aureus, Bacillus subtilis, Aspergillus Niger, and Aspergillus flavus. Results revealed that all synthesized scaffolds displayed superior activities than the standard drugs against various microbial strains. The synthesized compounds showed potential antimicrobial activity against Gram-positive, Gram-negative bacteria, and fungi.. KEYWORDS :Antimicrobial activity, Click chemistry, Microwave irradiation, 1,4-Disubstituted 1,2,3-triazoles, 1,2,4-Triazolo[4,3-a]pyridine.
Synthesis of Some New Schiff Base Derivatives of Simazine and Atrazine for In Vitro Antimycobacterial Activity
Authors: Mahyavanshi Jyotindra B. , Pandya Jayesh M. , Acharya Girish D.
Published: June 2024

This study presents the design and synthesis of some new Schiff base derivatives of simazine and atrazine series for in vitro antitubercular activity. The synthesis of target compounds 5a-h/6a-h was accomplished in two steps starting from simazine (1) and atrazine (2). The first common step involved nucleophilic substitution with 4-aminoacetophenone to give the corresponding 4-substituted derivatives 3/4. The obtained intermediates were subsequently converted to Schiff basses by reacting with various amines. The synthesized compounds were evaluated for potential medicinal properties against tuberculosis, with findings indicating that introducing specific substituents onto the s-triazine ring enhanced their antimycobacterial activity. Compounds featuring amine derivatives with alkyl and methoxy groups demonstrated the highest efficacy. These modified structures serve as promising templates for developing molecules effective against various pathogenic microorganisms, contributing to the drug discovery process for infectious disease treatment.. KEYWORDS :Antimycobacterial activity, Atrazine, Schiff base, Simazine, s-Triazine.
Principal Change Management Processes and Secondary School Goal Attainment in Cross River State, Nigeria
Authors:   Department of Vocational and Entrepreneurial Studies, University of Calabar, Nigeria, I. M. Idike , Barong Abang Maureen ,   Department of Vocational and Entrepreneurial Studies, University of Calabar, Nigeria, Akpo Atah Cletus ,   Department of Business Education Ebonyi State University, Abakaliki, Nigeria
Published: June 2024

The study investigated principals' change management processes and secondary school goal attainment in Cross River State, Nigeria. To meet the study's objectives, three research questions were posed, and three null hypotheses were developed to lead the investigation. The literature review was based on the variables and hypotheses that had been developed. For the study, a survey research design was used. The population of the study comprised two hundred and ninety (290) secondary school teachers in Yala Local Government Area in Cross River State. However, the sample size selected for this study comprised one hundred and sixty-two (162) secondary school teachers in the study area who answered the questionnaire. The main instrument used was a research questionnaire titled Principal Change Process and Secondary School Goal Attainment Questionnaire (PCMPSSGAQ), which had been verified by two researchers from the University of Calabar's Department of Vocational Education. Regarding the research questions, the acquired data was evaluated using the standard deviation as well as the mean. The degree of consensus or discord was calculated by taking the mean across the nominal scores assigned to each choice. The mean score of the scale was 2.50 on a 4-point rating scale. Comparably, the hypotheses were assessed using an independent t-test at the 0.05 level of significance. The results of the investigation indicate that staff training, communication of the change process, and change process supervision have a substantial influence on secondary school achievement of objectives. It was recommended that the secondary school board of Cross River State prioritize staff training and retraining programs in the secondary school system for goal achievement.
Analysis of Topics Perceived Difficult by Pre-service Mathematics Teachers and Lecturers in Colleges of Education in Niger State, Nigeria
Authors:   Department of Mathematics, Niger State College of Education, Minna, Nigeria., Usman Hassan , Kure Isah Danjuma ,   Department of Science Education, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Usman Hussaini ,   Niger State Teacher Professional Development Institute, Minna, Nigeria.
Published: June 2024

This study was conducted to investigate the topics perceived as difficult by pre-service mathematics teachers and Mathematics lecturers in Colleges of Education in Niger State, Nigeria. One Hundred and seven (107) 300 level Pre-service Mathematics Teachers and Seventeen (17) Lecturers were purposively selected from two (2) Colleges of Education in Niger State, Nigeria. A twenty-three items questionnaire named Mathematics Topic Analysis Questionnaire (MTAQ) with two sections was administered to respondents (Pre-service Mathematics Teachers and Mathematics Lecturers). The questionnaire was validated by experts, and its internal consistency was assessed using Cronbach's Alpha, which yielded a reliability coefficient of 0.87. Data analysis was done using Mean and Standard deviation and independent sample t-test. A criterion means of 2.5 was set as the basis for judgment. A mean score of 2.5 and above indicated an easy topic, while less than 2.5 indicated a difficult topic. Findings revealed that Pre-service Mathematics teachers perceived 9 topics as difficult to comprehend while 3 topics were perceived as difficult to teach by Mathematics lecturers. The study also showed that Pre-service Mathematics teachers’ gender has no significant influence on their perception of difficult topics in mathematics. It was therefore recommended that students should be encouraged and motivated to learn mathematics, curriculum developers should develop instructions that would improve students’ knowledge by laying more emphasis on the perceived difficulty areas in mathematics and further studies should be conducted to find out the factors responsible for the perceived difficulty and also if there is a relationship between perception and students’ achievement.
Influence of Gender Discrimination on Girl Child Education in Odogbolu Local Government Area of Ogun State, Nigeria
Authors:   Department of Educational Management, University of Benin, Benin City, Nigeria, Adegbesan Sunday Oduyemi , Oyelade Anthonia Oyebami ,   Department of Educational Management, Osun State University, Oshogbo, Nigeria
Published: June 2024

This study aims to investigate the prevalence of gender discrimination and its impact on girl child education in Odogbolu Local Government Area of Ogun State, Nigeria. The objectives of the study are to assess the level of awareness of gender discrimination in Odogbolu Local Government Area of Ogun State, to identify societal beliefs influencing girl child education, to explore factors hindering girl child participation in education, and to examine the effects of gender discrimination on societal development. The study utilized a descriptive survey method with a sample size of 120 respondents, including both male and female teachers from 10 schools in Odogbolu. A researcher-designed questionnaire with a validity index of 0.86 was employed for data collection. Data analysis was conducted using mean and standard deviation. The study revealed an alarming level of awareness regarding gender discrimination in Odogbolu, with a majority of girls being treated as inferior. Significant relationships between societal beliefs and girl child education were identified. Discrimination against the girl child was found to be more prevalent in rural areas. Factors such as early marriage, cultural issues, domestic violence, teenage pregnancy, and religious bias were identified as hindrances to girl child education. The effects of gender discrimination on societal development include dropout rates, mental health issues, inadequate female representation, poor academic performance among teachers, and limited access to education for girls. The major recommendations are to implement awareness programs to address gender discrimination, enforce policies to protect the rights of girl children, provide support systems for girls facing societal barriers, and promote community involvement in advocating for girl child education.
Analytical Comparison of Item Statistics Employing IRT 3PLM in WASSCE and NECO SSCE 2023 English Language Multiple Choice Tests
Authors:   Educational Evaluation and Counselling Psychology, University of Benin, Benin City, Nigeria,, Alexander Oghenerume Rioborue , Inwuototso Uyi-Osaretin Stella ,   Educational Foundations, University of Benin, Benin City, Nigeria
Published: June 2024

This assessment encompassed the analytical comparison of item statistics employing the Item Response Theory Three Parameter Logistic Model (IRT 3PLM) in WASSCE and NECO SSCE 2023 English Language multiple choice tests. Three hypothesised questions were articulated. In this study, a survey research design was utilised. This investigation’s population comprised 72,400 English Language SS 3 students in 384 public senior secondary schools in Ogun State. A multistage sampling procedure was applied to pick a sample size of 8,000 English Language SS 3 students. The assessment instruments used were WASSCE and NECO SSCE 2023 English Language multiple choice tests. The data collected were subjected to IRT 3PLM using jMetrik psychometric software to generate the item parameters. All hypothesised questions were tested for significance utilising independent samples t-test statistics. This assessment’s outcomes divulged a significant dissimilarity in the guessing parameter between WASSCE and NECO SSCE 2023 English Language multiple-choice items. However, no significant dissimilarities existed in the discrimination and difficulty parameters between the two. The pragmatic extrapolation of this analytical comparison accentuated in the findings alluded that employing IRT 3PLM to establish the item statistics before administering the tests could further enhance the quality of English Language multiple choice items developed by WAEC and NECO.
Challenges of E-Teaching During the Covid-19 Pandemic in Uganda Universities
Authors:   Department of Physical Sciences, School of Natural and Applied Sciences, Kampala International University, Kampala, Uganda, Olatide Olaniyan Ademola , Uzorka Afam ,   Department of Art and Sciences, College of Education, Open and Distance Learning, Kampala International University, Kampala, Uganda
Published: June 2024

The COVID-19 pandemic has forced a quick transition to online learning, which has presented teachers with many difficulties when delivering instruction from a distance. In the context of e-teaching, this study investigated the difficulties faced by academic staff members during the COVID-19 pandemic. Semi-structured interviews and focus group discussions were conducted as part of a qualitative research strategy with faculty members with e-teaching experience during the pandemic. The research identified several challenges related to technology, pedagogical adaptation, student engagement, assessment and feedback, workload management, and the effect on faculty members' emotions and psychological health. These difficulties highlighted the requirement for technological competence, pedagogical training, support structures, and resources to improve the experience of e-teaching. Comprehensive faculty development programs, inclusive instructional design, a variety of evaluation techniques, assistance with workload management, and attempts to enhance faculty well-being are among the recommendations. By addressing these issues, educational institutions can manage the difficulties of e-teaching in emergencies and ensure that students receive high-quality instruction in virtual classrooms.
MEWUJUDKAN LINGKUNGAN BERSIH MELALUI KOLABORASI PENGABDIAN MASYARAKAT DI DESA MEKARSARI
Authors: Aminullah Aminullah , Subrata I Gusti Made , Jaya Nenet Natasudian , Marini Ida Ayu Ketut , Solihun Siti , Zulaifi Reza , Zainuddin M. , Sativa Denianto Yoga , Sardi Idris , Zainab Siti
Published: June 2024

community service in Mekarsari Village. Methods for implementing service include: forming a service team, preparing service needs, cleaning the environment and providing rubbish bins.
Service activities carried out include: 1) Formation of a service team consisting of academics, the community and village government. 2) Preparation for the needs for implementing the service begins with directing and checking tools and materials in the form of brooms, shovels, buckets, plastic, hoes and sickles prepared by the community. 3) Environmental clean-up is carried out around the Malaka hamlet kindergarten to maintain the comfort and health, especially of children, as well as to create interest and life for tourists because it is on the tourist route, and 4) procurement of rubbish bins, procurement of rubbish bins purchased from local community wickerwork and then painted as markers and fixed to make them look different or better
Genelden Özele Türkiye'de Aleviler ve Nusayriler (Hatay Bölgesi ve Hacıbektaş Kasabasında Yapılan Saha Çalışmaları Bağlamında)
Authors: Zhigulskaya Daria
Published: June 2024

Coğrafi konumu; etnik, dini ve kültürel heterojenliği göz önüne alındığında modern Türkiye hem oryantalistlerin hem de küresel anlamda siyasi ve toplumsal meselelerle ilgilenen geniş bir kitlenin özel olarak ilgisini çekmektedir. Bu bağlamda, Türk Aleviliği ve Türk Alevileri konusu son yıllarda hususi bir ilgi görmektedir. Ancak Türkiye Alevilerinin sıklıkla Suriye Nusayrîleri ile karıştırılmaları, Türk Aleviliği kavramının ciddi anlamda tahrifata uğramasına neden olmaktadır. Ağırlıklı olarak ülke nüfusunun %12’sini teşkil ettikleri Suriye’de varlık gösteren Nusayrîler, buna karşın Türkiye’de yaklaşık 350.000 kişilik bir cemaattir. Çoğunlukla Hatay, Adana ve Mersin’in güney bölgelerinde yaşarlar ve etnik bakımdan Arap’tırlar. Bu makale, Hatay bölgesi ve Hacıbektaş kasabasında yürütülen saha çalışmalarındaki bulgulara dayanmakta ve Türkiye’deki Alevi ve Nusayrî cemaatlerinin bölgesel görünümlerine dikkat çekmeyi amaçlamaktadır. Bu çalışmada her iki inancın karakteristik özellikleri, iki toplumdaki toplumsal örgütlenme gelenekleri ve ibadet biçimleri üzerinde durulmuştur. İki inanç arasındaki benzerlikler özetlenmiş ve ayırt edici özellikler vurgulanmıştır.
THE EFFECT OF SOURSOP LEAF TEA ON REDUCING BLOOD SUGAR LEVELS IN DIABETES MELLITUS PATIENTS
Authors: Rustanti Elly , Naben Faustina , Sari Gevi Melliya , Setiawan Roni
Published: June 2024

Background: In Indonesia, many people do not pay attention to healthy lifestyles in order to maintain stable blood sugar to prevent diabetes mellitus, which increases every year.
Objective: The aim of this research was to determine the effect of soursop leaf tea on reducing blood sugar levels in diabetes mellitus sufferers at the Dukuh Klopo Community Health Center, Peterongan, Jombang.
Method: The research design was a pre-experimental - one group pre test-post test design. The population in this study was 153 people, all sufferers of diabetes mellitus at the Dukuh Klopo Community Health Center using purposive sampling technique, a sample of 23 people. The independent variable is soursop leaf tea. The dependent variable is a decrease in blood sugar levels in diabetes mellitus sufferers. Data collection uses SOP and observation sheets with the Wilcoxon statistical test.
Results: Based on the research results, it was discovered that all 23 respondents (100%) had high blood sugar levels before being given soursop leaf tea therapy. Meanwhile, after being given therapy, some respondents, namely 12 respondents (52%) were in the moderate category and 11 respondents (48%) were in the normal category. The results of the Wilcoxon test at a significance level of α = 0.05 showed that ρ<α or 0.000 < 0.05, so H1 was accepted and H0 was rejected, which means that there is an effect of soursop leaf tea on reducing blood sugar levels in diabetes mellitus sufferers at the Dukuh Klopo Community Health Center, Peterongan , Jombang.
Conclusion: Giving soursop leaf tea can reduce blood sugar in diabetes mellitus sufferers and is expected to be an alternative intervention to reduce blood sugar, because soursop leaves can improve pancreatic cells by increasing their granulation. Apart from that, the high antioxidants in soursop leaves can reduce free radicals that come from hyperglycemia.
การพัฒนาสิ่งทอย้อมสีธรรมชาติจากกากเมล็ดโกโก้กับแนวคิดแฟชั่นยั่งยืน
Authors: อรัญนารถ ศิวรี
Published: June 2024

การพัฒนาสิ่งทอย้อมสีธรรมชาติจากกากเมล็ดโกโก้กับแนวคิดแฟชั่นยั่งยืน เป็นบทความวิชาการจากการสังเคราะห์ข้อมูลองค์ความรู้ที่เป็นส่วนหนึ่งของโครงการนวัตกรรมอุตสาหกรรมผลิตภัณฑ์ไลฟ์สไตล์ จากจังหวัดน่านสู่สากล เพื่อการท่องเที่ยวเชิงสร้างสรรค์ กรณีศึกษากลุ่มผ้าทอไทลื้อบ้านเก็ต อำเภอปัว จังหวัดน่าน ภายใต้โครงการการพัฒนาการท่องเที่ยวเชิงสร้างสรรค์ โดยมีวัตถุประสงค์เพื่อนำเสนอองค์ความรู้จากภูมิปัญญาท้องถิ่น อันนำไปสู่การสังเคราะห์แนวทางการพัฒนาสิ่งทอย้อมสีธรรมชาติจากกากเมล็ดโกโก้ด้วยแนวคิดแฟชั่นยั่งยืน ซึ่งเป็นการหลอมรวมระหว่างสิ่งแวดล้อม สังคม และเศรษฐกิจ ทั้งนี้การย้อมสีธรรมชาตินั้นเกี่ยวข้องกับมิติทางด้านสังคมชุมชน เนื่องจากพืชที่ให้สีนั้นเป็นพืชในท้องถิ่น ทำหรือผลิตขึ้นโดยคนในชุมชนซึ่งเกี่ยวข้องกับทรัพยากรธรรมชาติ และทรัพยากรมนุษย์ ผ่านสิ่งทอทุนวัฒนธรรม  และในด้านเศรษฐกิจนั้นสิ่งทอที่สร้างสรรค์ด้วยเทคนิคการย้อมสีธรรมชาติสามารถสร้างอาชีพและรายได้ให้กับคนในชุมชน ผ่านการแปรรูปเป็นสินค้าและผลิตภัณฑ์แฟชั่นไลฟ์สไต
INTERNATIONAL MARKET SELECTION FOR FROZEN SHRIMP EXPORTS FROM THAILAND: AN INTEGRATION OF CAGE DISTANCE FRAMEWORK AND DATA ENVELOPMENT ANALYSIS
Authors: Inkaew Amondech , Phokawattana Onpawee
Published: June 2024

Purpose – This research aims to assess and rank the efficiency of countries where Thailand exported frozen shrimp to, and to provide actionable insights for policymakers and stakeholders in the frozen shrimp export industry based on the efficiency scores.Methodology – This study employed the integration of the CAGE Distance Framework and Data Envelopment Analysis (DEA) to investigate the dynamics of international market selection for frozen shrimp exports from Thailand. The study evaluated and ranked the effectiveness of 20 nations that were chosen based on 2022 export values exceeding 1,000,000 US Dollars. The DEA BCC model, utilizing linear programming techniques, categorized these countries as Decision Making Units (DMUs), assessing their efficiency to determine how efficiently a DMU produced outputs given a set level of inputs.Results – Results from the DEA analysis highlighted efficiency leaders with an efficiency score of 1, such as China, the United States, Japan, Taiwan, Hong Kong SAR, Australia, Myanmar, Vietnam, Singapore, Cambodia, and Laos. Additionally, it identified intermediate performers with room for improvement and countries with opportunities for optimization.Implications – This integrated methodology served as a valuable guide for future students and professionals navigating the complexities of the global frozen shrimp trade.Originality/Value – The integration of the CAGE framework with DEA offered a unique approach that had not been explored in previous applications. It established a pioneering approach for policymakers, practitioners, and entrepreneurs.
Sugarcane Yield Prediction in Bihar using Biometric Characteristics
Authors: M. Muhammed Irshad , Kumar Mahesh , Kamat D. N.
Published: June 2024

This study focuses on creating predictive models for sugarcane yield in Bihar, utilizing various biometrical characteristics. The research involved collecting observations on specific plant biometrical traits from 50 farmers’ fields of Samastipur, West Champaran and East Champaran Districts of Bihar. Simple random sampling was employed for field selection. Various regression analyses were conducted to identify the optimal combination. The accuracy of the model was assessed by comparing the actual yield from 10% of the observations not used in model development with their predicted values. The results demonstrated a close resemblance, with a margin of error ranging from 5.91% to 8.36%. The forecasted sugarcane yield for Bihar, based on the proposed model, is 847.82 q/ha.
PREDICTIVE EVALUATION OF THE TOXICITY AND ADVERSE EFFECTS OF PLANTANONES A-D
Authors: De Sousa Damião Sampaio , Barbosa Belarmino Anthony , Mendes Francisco Rogênio Da Silva , Marinho Gabrielle Silva
Published: June 2024

Chronic prostatitis, a common condition in urology, is responsible for inflammation of the prostate tissues and can be aggravated by factors such as oxidative stress and inflammatory responses. Conventional treatments, such as anti-inflammatories, hormone therapies, and surgery, have shown limited efficacy, so new treatment methods are needed. Components of the herb Hosta plantaginea may offer new therapeutic approaches due to their anti-inflammatory, antibacterial, and antioxidant properties. Studies on obtaining new pharmacological compounds derived from H. plantaginea have obtained plantanones A-D, which belong to the flavonoid class and have anti-inflammatory activities. In this sense, the study aims to predictively evaluate the toxicological safety of plantanones in rats, to understand their adverse effects as drugs. The analysis was based on the GUSAR© and ProTox© tools to assess toxicity (LD50) through the routes of administration (intraperitoneal, intravenous, oral, and subcutaneous) and the toxicological endpoints in rats. GraphPad Prism® software was also used for statistical validation using the one-way ANOVA and normality tests. The results indicate that plantanones are possibly dangerous if ingested, that they can generate toxic effects via the IP and IV routes, and that plantanones A-C cause immunotoxicity. Further studies evaluating the toxicity of plantanones in organs and in vivo and in vitro tests could be carried out to corroborate the results presented.
SIGILO DO NOME DAS VÍTIMAS EM CRIMES QUE APURAM VIOLÊNCIA DOMÉSTICA
Authors: Cardoso Pacheco Leonides , Jacob Alexandre
Published: June 2024

O artigo visa analisar a alteração mais recente na Lei Maria da Penha, que garante sigilo ao nome das vítimas de violência doméstica e familiar a fim de evitar a revitimização. Para tanto, o trabalho perpassa por pontos cruciais para que se chegue à discussão adequada e à conclusão, indo então desde o histórico das Leis favoráveis às mulheres no Brasil até a legislação atual. O foco é evitar a revitimização, que consiste em expor a vítima de crime a situações que reativam o sofrimento associado ao evento original. Isso pode acontecer em diferentes contextos, como no sistema jurídico, na mídia ou mesmo em interações sociais, quando a vítima é confrontada com julgamentos, dúvidas ou tratamentos que a fazem reviver as emoções dolorosas do evento traumático. Na violência doméstica, por exemplo, a revitimização pode ocorrer quando a vítima é culpabilizada ou não recebe o apoio adequado, o que pode agravar seu sofrimento e dificultar sua recuperação. Dessa forma, o sigilo é crucial no processo de minimização dos impactos causados à vítima, sendo também um encorajador para mais denúncias.
AÇÃO DO LÚPULO EM PACIENTES QUE FAZEM USO DE MEDICAMENTOS PSICOTRÓPICOS
Authors: Nunes Klemeson , Aline Ribeiro de Souza  , Larissa Pereira Batista  , Pedro Emílio Amador Salomão
Published: June 2024

Este estudo explora a interação do lúpulo (Humulus lupulus) com medicamentos psicotrópicos, destacando seus potenciais benefícios terapêuticos e os riscos associados. O lúpulo, conhecido por suas propriedades sedativas e ansiolíticas devido a compostos como alfa-ácidos e 8-prenilnaringenina, pode ser usado para tratar distúrbios de ansiedade e insônia. No entanto, quando combinado com medicamentos psicotrópicos como antidepressivos e ansiolíticos, há o potencial de potencializar os efeitos sedativos, aumentando o risco de sedação excessiva e comprometimento cognitivo. Além disso, o lúpulo pode influenciar a farmacocinética dos medicamentos, alterando sua absorção e metabolismo através do sistema citocromo P450. Este estudo destaca a necessidade de monitoramento clínico rigoroso ao considerar a combinação de lúpulo e medicamentos psicotrópicos, visando maximizar os benefícios terapêuticos enquanto minimiza os riscos para a saúde dos pacientes.