bluuebunny/crossref_metadata_2025 huggingface dataset:
Growth and survival assessment from African lungfish (Clarias gariepinus) and its hybrid with two species of heterobranchus
Authors: Abdulraheem Ikililu , Abubakar Musa Idi-Ogede
Published: August 2024

Obtaining good quality and quantity of fish seeds for increasing fish production is a major quest by fish farmers. This study examined the growth responses and survival of Clarias gariepinus and two species of heterobranchus. One thousand five hundred (1500) fry (28-day after hatched) were randomly selected from each of the three crosses of Clarias gariepinus (T1), C. gariepinus x Heterobranchus longifilis (T2) and C. gariepinus x Heterobranchus bidorsalis (T3) broodstocks. They were stocked separately in triplicate at a stocking rate of 500 fish per replicate and reared for 90 days. The data were analysed for significant differences (P<0.05) by Analysis of Variance (ANOVA). There was no significant difference in the growth parameters but fish in T3 had the highest value of mean weight gain while T1 had the least. No significant difference (p>0.05) was observed in the body weight gains from day 40 to day 90 except at day 70 where T3 had the highest weight gain (18.97 g) which was significantly different (p<0.05) to the value recorded in T1 (18.20 g) but not significantly different (p>0.05) to the value recorded in T3 (18.97 g). The results of length increment showed that the growth pattern from day 0 to day 80 were similar. A little difference was observed at day 90 with T3 >T2>T1. The fish in T1 (Clarias gariepinus) had the highest significant percentage survival (89.60%). The results of water quality parameters showed that the mean temperature was 28oC, pH 6.8, dissolved oxygen 5.6 mg/l and turbidity 5.45 NYU. The culture of C. gariepinus by farmers will improve their output and consequentially increase in profit.Keywords: aquaculture; fish breeding; hybrids; weight gain
Size distribution and growth parameters of blue swimming crab (Portunus pelagicus, Linnaeus 1758) in Awur Bay, Jepara
Authors: Azzahra Rizqina Nafa Nur , Saputra Suradi Wijaya , Rudiyanti Siti
Published: August 2024

Blue swimming crab (Portunus pelagicus) is a fishery commodity that has important economic value. One of the catch landings in Teluk Awur, Jepara is blue swimming crab. Intensive crab catching carried out with small sizes has an effect on decreasing crab stocks in the waters. This study aims to determine the size distribution, the relationship between carapace width and weight, growth parameters and recruitment patterns. The research was conducted in May, June, July and August 2022 in the waters of Teluk Awur, Jepara. Sampling using systematic sampling method. The data collected is carapace width (mm) and crab weight (grams). Data analysis was performed using FiSAT II software. The results of the analysis of the relationship between carapace width and weight showed that the growth of the male crab was positive allometric and the growth of the female crab was isometric, with the equation of the male crab W = 0.0000214cW3.251 and the female crab W = 0.0000232cW3.220. The growth parameters obtained by the equation of the male and female crabs were cWt = 158,55(1- e(-1,2(t+0,083))], and cWt = 158.55(1 – e(-0.67(t+0.152) ))). The peak of male crab recruitment was in October at 22,71%, while the female crab was in May at 13,52%, indicating that in that month new crab individuals were added. Based on these results, the stock of crab resources in Jepara's Awur Bay must always be considered and always support the recruitment process of crab. Beside that, the goverment can enforce management of crab fishing.Keywords: Allometric; Carapace Width; Crab; Recruitment
Efficiency analysis of catfish (Pangasius sp) marketing channels Balai Benih Ikan (BBI) Terantang
Authors: Susanto Adha , Satriansah Erman , Basriwijaya Kiagus Muhammad Zain
Published: August 2024

This study aims to analyze farmer's share, marketing margins, profit ratio, and marketing channel efficiency of catifish (Pangasius sp.) BBI Terantang in Sukamara and Balairiam District. The research method is a survey method by conducting direct observations and interviews. The data used were primary data and secondary data collected during September 2022 to June 2023. The data obtained was then analyzed using qualitative and quantitative descriptive analysis. The results showed that there were three types of marketing channels for BBI Terantang catfish, namely I: BBI Terantang and consumers, II: BBI Terantang, retailers, and consumers, and III: BBI Terantang, collectors, retailers, and consumers. Marketing channel I has a farmer's share value of 100%. The highest marketing margin occurred in marketing channel III with a total margin of Rp. 7,500.00-/kg. The profit ratio in marketing channels II and III benefits retailers and collectors with ratios of 7 and 3.3. As for the marketing efficiency of fresh catfish, all marketing channels are effective.Keywords: Catfish; Farmer's Share; Marketing Efficiency; Marketing Margin; Profit Ratio.
Utilization of Indigofera zollingeriana leaves meal in feed formulation to color brightness and growth in koi fish (Cyprinus carpio)
Authors: Mukti Retno Cahya , Yulisman Yulisman , Irmawati Irmawati , Putra Muhamad Sadina
Published: August 2024

This study aims to determine the effect of the addition of Indigofera zollingeriana in feed formulations with different doses on the color brightness of koi fish. The research design was Completely Randomized Design (CRD) with five treatments and three replications. Treatment P0 was control (without the use of Indigofera leaf meal), P1 was the addition of 5% indigofera meal, P2 was the addition of 10% indigofera meal, P3 was the addition of 15% indigofera meal, and P4 was the addition of 20% indigofera meal. Fingerlings measuring 6 ± 1 cm with a stocking density of 1 fish for 2 L were reared for 30 days in this study. The results showed that P2 with a percentage of 10% Indigofera zollingeriana meal was the best treatment for the brightness of koi fish color (27.23). Still, they had no significant effect on the growth of absolute length (1.04 cm) and absolute weight (1.05 g), feed efficiency (23.08%), and survival rate (100%). The water quality obtained during maintenance was temperature 26-27oC, pH 6.1-7.2, dissolved oxygen 5.2-6.3 mg/L, and ammonia 0.02-0.036 mg/L.Keywords: Fish Color Brightness; Indigofera zollingeriana; Koi Fish
Supplementation of lysine and probiotics in artificial feed based on local raw materials on feed quality and feed conversion ratio of bileh fish (Rasbora sp.)
Authors: Islama Dini , Diansyah Sufal , Samuki Khairul , Vito Bastian , Febrina Citra Dina
Published: August 2024

AbstractThis study aims to determine the effect of lysine and probiotic supplementation in artificial feed based on local raw materials on feed quality and feed conversion ratio of bileh fish (Rasbora sp.). This research was carried out from August to September 2023 at the Hatchery and Laboratory of Systems and Technology and the Aquaculture Environment, Faculty of Fisheries and Marine Sciences, Teuku Umar University. In this study, bileh fish measuring 2 - 2.5 cm long were used as test fish. The experimental design used was a non-factorial Completely Randomized Design (CRD) with 4 treatments and 3 replications. The level of treatment applied in feed formulation is feed based on local raw materials as a control (P0), feed based on local raw materials with 1.2% lysine supplementation (P1), 1.4% (P2), 1.6% (P3), 1.8 % (P4) and probiotics 15 ml/kg feed. Feed is given at satiation 3 times a day. The test parameters observed were the quality of the feed produced, daily growth rate and feed conversion ratio of bileh fish (Rasbora sp.). The research results showed that lysine and probiotic supplementation in artificial feed based on local raw materials gave the same response to the quality of the feed produced, but had a significant effect on the daily growth rate and feed conversion ratio of bileh fish. The best daily growth rate and feed conversion ratio were obtained in the P3 treatment.Keywords: Artificial feed based on local raw materials; feed quality; feed conversion ratio; Rasbora sp.
Identification of microplastic content in milkfish ponds in Lontar Village, Serang Regency
Authors: Yogi Yonita Nabila , Putra Achmad Noerkhaerin , Aryani Desy
Published: August 2024

Microplastics measuring < 5 mm can easily enter the fish's body through the respiratory system and digestive system. The aim of this research is to calculate the abundance of microplastics and determine the types contained in the bodies of milkfish, water and sediment in the Lontar Village Pond, Serang Regency. There are 6 stations, 4 fish samples were taken from each station, water samples were taken using a plankton net and sediment samples were taken using individual pipes at each station. The number of fish samples was 24 fish, meat, intestine, stomachs and gills were taken. Fish organs were destroyed using 10% KOH. Samples were incubated for 24 hours until the organic material was destroyed. Then filtered using Whattman No 42, and dried using an oven at 60ºC for 1 hour. Likewise, filtering of water and sediment samples is carried out. The types of microplastics found were fragments, fibers and films. The highest abundance was in the gills and intestines with an abundance of 11 per individual. The highest abundance of microplastics in the water in Lontar Village ponds is the fragment type with a total of 5 per/20 mL at station 3 and the film type with a total of 5 per/20 mL at station 6 and in the milkfish pond sediments of Lontar Village the highest abundance of microplastics is 1 per/25 gr. The types of polymers found in the digestive tract of milkfish are Polycarbonate (PC), Acrylonitrile butadiene styrene (ABS), Latex, Polystyrene (PS), Nylon, and Polytetrafluoroethylene (PTFE).Keywords: Aquaculture; Lontar; Microplastics; Milkfish
UNDERSTANDING SOCIAL MEDIA APPLICATION FOR SUSTAINABLE DEVELOPMENT GOALS
Authors: Singh Pooja , Singh Shrikant
Published: August 2024

In recent years, social media has emerged as a powerful medium for promoting and achieving Sustainable Development Goals (SDGs). This paper explores the multifaceted role of social media applications in advancing the 17 SDGs outlined by the United Nations. By analyzing literatures, user engagement metrics, and usage strategies, we aim to understand how social media can drive awareness, mobilize communities, and foster collaboration among stakeholders. The study identifies key platforms and tactics that have proven effective in influencing public opinion, disseminating critical information, and key purpose for using social media toward sustainability. Furthermore, it highlights the challenges of applications, digital divide, and correlation among different sustainable goals (Quality Education, Good Health and Well Being, Sustainable Communities, Climate Action) concerns that could undermine these efforts. Our findings suggest that when strategically leveraged, social media not only enhances communication and outreach but also accelerates the implementation of sustainable practices globally. However, there are total sample taken for study is 500 out of which 466 have been collected, it includes descriptive study with survey method to collect responses. This paper concludes with recommendations for policymakers, NGOs, and social media companies to utilize the full potential of these digital platforms in achieving a more sustainable future.
Abordaje de las genodermatosis desde la medicina de precisión: reporte de casos
Authors: Zúñiga-Espitia Iván Darío , Moreno Giraldo Lina Johanna , Satizábal Soto José María
Published: August 2024

La ictiosis epidermolítica (EI), una enfermedad genética autosómica dominante que hace parte de las ictiosis queratinopáticas (KPI) (1). Afecta a 1 de cada 200.000 a 300.000 recién nacidos, como resultado de una variante en el gen KRT1 o KRT10 que codifica la queratina 1 y 10 respectivamente; proteinas presentes en los queratinocitos de las capas suprabasales de la epidermis, donde forman haces tonofibrilares y juntas son marcadores tempranos de diferenciación celular (2).
Los pacientes al nacimiento presentan eritrodermia y ampollas, como consecuencia de la fragilidad del citoesqueleto de las células epidérmicas y el colapso de los filamentos de queratina. Los cambios cutáneos con el tiempo evolucionan a hiperqueratosis (3). Se presentan dos casos de pacientes con EI, en los que el estudio genético jugó un papel importante en el diagnóstico específico, a fin de instaurar un tratamiento dirigido, establecer pronóstico y riesgo de heredabilidad, acercándonos a la medicina de precisión.
Lupus eritematoso túmido. Parte II
Authors: Ocampos Montiel Sara Elisa , Re-Domínguez Lorena , Aldama-Caballero Arnaldo
Published: August 2024

El lupus eritematoso túmido es una forma rara de lupus eritematoso cutáneo que se caracteriza por placas eritematoedematosas que desaparecen sin dejar cicatriz. Las lesiones son inducibles por la fotoexposición por lo que cursa en brotes. Histopatólogicamente se caracteriza por un infiltrado linfohistiocitario perivascular, perianexial y depósitos de mucina en dermis papilar y reticular además de la ausencia de alteraciones a nivel epidérmico o cambios leves.
Se presenta el caso de un paciente varón de 55 años que consulta por una lesión eritematosa en rostro en quién se sospecha, en primera instancia, enfermedad de Hansen por su frecuencia y nuestra epidemiología regional.
Secreto profesional en medicina. Parte II
Authors: Maya José María
Published: August 2024

Se presenta el caso de un paciente con patología psiquiátrica, que, en consulta, comunica información al médico especialista en psiquiatría la cual revela riesgo para personas cercanas al paciente. El médico especialista, se abstiene de revelar esta información por considerar que es su obligación no revelarla por formar parte del secreto profesional que él se ha comprometido como médico a guardar.
El paciente en un momento de obnubilación asociado a su patología, produce un daño irreversible a una persona muy cercana, el cual pudiera haberse evitado si ella hubiera sido advertida de la situación mental del paciente y hubiera tomado precauciones al entrar en contacto con él.
El médico es cuestionado por su actuación y sancionado por las autoridades civiles y el tribunal de ética.
Se analiza el caso desde la bioética dejando claro el concepto de secreto profesional en medicina, sus alcances y limitaciones. Se enuncian y explican las causales que permiten revelar el secreto profesional.
A Kapudanpasha Of Hungarıan Orıgın Gazı Pıyale Pasha And Foundatıon Works In Chıos
Authors: TAŞ Mehmet
Published: August 2024

Osmanlı tarihinde kaptanıderyalık yapmış devşirme kökenli devlet adamları vardır. Bunlardan bazısı Zağanos Paşa, Gedik Ahmet Paşa, Kılıç Ali Paşa, Çığalazade Sinan Paşa ve Zurnazen Mustafa Paşa gibi isimlerdir. Bunlar kaptanıderyalık
gibi askeri bir görevi yerine getirmelerinin yanı sıra vakıf eserleri meydana getirerek sosyal faaliyetlerde bulunmaktan geri kalmamıştır. Bu kişilerden bir tanesi Piyale Paşa’dır. Piyale Paşa, Kanuni Sultan Süleyman(1520-1566)
ve II. Selim (1566-1574) döneminde 14 yıl kaptan-ı derya görevinde bulunmuş ve önemli zaferler kazanmış bir Osmanlı devlet adamıdır. Macaristan doğumlu olup 1526 yılındaki Mohaç Savaşı’ndan Türklere esir düşmüştür. Piyale Paşa,
İstanbul’da kurduğu vakıf yoluyla birçok cami, çeşme, mescit, medrese ve suyolu inşa ettirerek toplum yaşamında etkili olmuş bir isimdir. Piyale Paşa’nın vakıf eserlerinin yoğunlaştığı yerlerden birisi Sakız Adası’dır. Buradaki
vakıf eserleri ile bunların finansmanı için tahsis edilen taşınmazların bilinmesi tarihe mal olmuş bu kişinin daha iyi anlaşılmasını sağlayacaktır.
Analysis of Sustainable Food Sector Development in the Sumatra Island
Authors: Suirlan Rita , Nurnaningsih Nurnaningsih
Published: August 2024

The research aims to analyze the development of food security through indicators of the sustainable food sector on the island of Sumatra in 2018-2022. Food sector indicators include the number of poor people, food inflation, rice consumption per capita, insufficient food consumption, and food insecurity. Food security indicators use the food security index. The research method is quantitative through secondary data collection with panel data analysis from cross section results of 10 provinces on the island of Sumatra and time series data for 2018-2022. The approach used, namely CEM,FEM, REM. The research findings show that the food inflation variable has a positive and significant effect on the food security index, the poor population variable, rice consumption per capita, insufficient food consumption has a positive and insignificant effect on the food security index. Population with food insecurity has a negative and insignificant effect on the food security index.
Systematic Literature Review: A Fun Organic Chemistry Learning Experience with Educational Games
Authors: Satari Clarysa , Wiji Wiji , Widhiyanti Tuszie , Mulyani Sri
Published: August 2024

This article examines organic chemistry educational games developed between 2017-2023. The purpose of this study is to find out the types of educational games that are most developed, organic chemistry materials that have been developed in the form of educational games, and the positive impact of educational games in studying organic chemistry. The method used in this study is a systematic literature review. The systematic literature review is carried out in three stages, namely the planning stage, the implementation stage, and the reporting stage. Based on the results of the study, 38 articles were obtained by the criteria and further analysis was carried out. The results of the analysis show that organic chemistry educational games are developed with various types of games both in digital and non-digital forms. The most developed organic chemistry educational games are strategy video games and card games. The most developed material in the form of educational games is the molecular structure of organic compounds which is shown to deepen students' understanding in organic chemistry courses.
ANTI-HYPERLIPIDEMIA ACTIVITY IN THE VIVO TEST FROM A COMBINATION OF AVOCADO LEAF EXTRACT (Persea americana Mill) AND GINGER RHIZOME (Curcuma xanthorrhiza Roxb) IN MICE WITH HYPERCHOLESTEROLEMIA
Authors: Farahdina Chairani  , Maszahrotul Pembayun  , Yusransyah  , Abdillah Mursyid
Published: August 2024

Herbal and traditional medicine are two of the main types of treatment in developing countries, including Indonesia. Hyperlipidemia is a condition in which cholesterol levels in the body exceed normal limits, impacting cardiovascular disease. Avocado leaves and temulawak rhizomes have been shown to have antihyperlipidemic effects in animals. This study aimed to determine the anti-hyperlipidemic activity of avocado leaf (Persea americana Mill) and temulawak rhizome (Curcuma xanthorrhiza Roxb) combination extract in cholesterol levels of white male mice Sprague Dawley strain. The subjects of this study consisted of 20 white male mice Sprague Dawley strain (Rattus novergicus) and were divided into five groups: F1 (standard); F2 (hypercholesterolemic group); F3 (1:1 treatment group); F4 (1:2 treatment group); and F5 (2:1 treatment group). The induction was conducted for 14 days, while the treatment was carried out for seven days. All data were analyzed using the Kruskal-Wallis and Mann-Whitney tests. The combination extract of avocado and temulawak rhizome has an anti-hyperlipidemic activity. Giving a combination extract of avocado leaf and temulawak rhizome to all treatment groups significantly reduced total cholesterol levels in mice (p = 0.028). Avocado leaves and temulawak rhizomes have potential antihyperlipidemic activity derived from flavonoids. In this study, the potency of the extract efficacy can be achieved when given in combination.
AKTIVITAS ANTIDEPRESAN MINYAK ATSIRI BIJI PALA (Myristica fragrans) TERHADAP MENCIT JANTAN SWISS WEBSTER (Mus musculus)
Authors: Nabila Riadatun , Inaratul Rizkhy Hanifah  , Dian Marlina  , Hery Muhamad Ansory
Published: August 2024

Minyak atsiri biji pala (Myristica fragrans) diketahui memiliki efek menenangkan, tetapi belum banyak bukti ilmiah terkait dosis efektif minyak atsiri biji pala (Myristica fragrans) sebagai antidepresan. Tujuan penelitian ini adalah untuk mengetahui dosis optimum minyak atsiri biji pala (Myristica fragrans) yang memberikan aktivitas antidepresan dalam meningkatkan aktivitas eksploratori dan menurunkan imobilitas mencit jantan galur Swiss Webster. Penelitian ini menggunakan 2 metode, yaitu Forced Swimming Test untuk mengamati imobilitas dan Open Field Test untuk mengamati central square dan rearing dengan variasi dosis 5 mg/KgBB mencit, 10 mg/KgBB mencit, 20 mg/KgBB mencit dan amitriptillin sebagai kontrol positif. Hasil penelitian menunjukkan dosis optimum minyak atsiri biji pala (Myristica fragrans) adalah 5 mg/KgBB mencit yang mampu menurunkan durasi imobilitas dan meningkatkan aktivitas eksploratori mencit. Kelompok dosis 5 mg/KgBB mencit memiliki nilai sig.(<0.05) dengan kontrol positif amitriptilin pada analisis ANOVA Post Hoc.
PENGUJIAN AKTIVITAS ANTIOKSIDAN SERTA PENETAPAN KADAR FLAVONOID EKSTRAK ETANOL DAUN SIRIH MERAH (Piper ornatum N.E.Br.) DENGAN METODE EKSTRAKSI MASERASI DAN ULTRASOUND-ASSISTED EXTRACTION
Authors: Lukmayani Yani , Giffar Abdiljabbar Najmudin  , Kiki Mulkiya Yuliawati
Published: August 2024

Tanaman sirih merah (Piper ornatum N.E.Br.) telah digunakan secara empiris dan terbukti memiliki berbagai macam aktivitas farmakologi. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan serta kadar flavonoid ekstrak etanol daun sirih merah dengan metode ekstraksi maserasi dan ultrasound-assisted extraction (UAE). Aktivitas antioksidan dinyatakan dengan nilai IC50 sedangkan kadar flavonoid dinyatakan dalam nilai QE (Quercetin equivalent). Daun sirih merah diekstraksi menggunakan pelarut etanol 96% dengan metode maserasi dan Ultrasound-assisted extraction (UAE) dengan variasi waktu 10, 20, 30, 40 menit. Penentuan aktivitas antioksidan dilakukan dengan metode DPPH dan penetapan kadar flavonoid secara spektrofotometri dengan pereaksi AlCl3. Hasil uji antioksidan menunjukkan bahwa aktivitas antioksidan ekstrak maserasi memiliki nilai IC50 36,54 ppm sedangkan ekstrak ultrasonik 40 menit memiliki nilai IC50 sebesar 30,54 ppm. Hasil penetapan kadar flavonoid ekstrak maserasi dan ultrasonik 40 menit menunjukkan kadar flavonoid secara berturut-turut sebesar 4,07 mgQE/g dan 4,32 mgQE/g ekstrak. Hasil pengujian menunjukkan bahwa Ultrasound-assisted extraction merupakan metode ekstraksi yang menghasilkan aktivitas antioksidan serta kadar flavonoid yang lebih baik daripada metode maserasi.
FORMULASI DAN EVALUASI MASKER GEL PEEL OFF EKSTRAK ETANOL 70% DAUN SAWO MANILA (MANILKARA ZAPOTA L.)
Authors: Wahyudin Bin Jamaludin  , Rifka Azizia  , Aristha Novyra Putri
Published: August 2024

Ekstrak etanol 70% daun Sawo Manila (Manilkara zapota L.) mengandung senyawa flavanoid, dan fenolik memiliki aktivitas antioksidan sangat kuat dengan IC₅₀ sebesar 8,26 µg/m sehingga berpotensi dikembangkan dalam bentuk sediaan farmasi untuk kulit wajah, salah satunya yaitu masker gel peel off. Tujuan dari penelitian ini adalah untuk menentukan formula yang paling optimal berdasarkan variasi konsentrasi film forming PVA dan gelling agent PVP K30. Penelitian ini dilakukan dengan metode eksperimental dengan variasi PVA 12%, 13%, 14%, dan PVP K30 1%, 5%, 10%. Hasil penelitian organoleptis menunjukkan warna kuning tua, kuning, dan kuning muda, berbau khas, berbentuk semi solid dan berupa sediaan yang homogen dengan pH berkisaran 4,9–5,7, viskositas 19046-19626 mPa.s, daya sebar 5,5-9,5 g.cm/sec, waktu sediaan mengering 12,84-20,48 menit, dan elastisitas 8,3-9,6 cm. Berdasarkan Hasil uji stabillitas menunjukan F5, F6, dan F8 memiliki nilai p-value (>0.05) sehingga dapat dinyatakan bahwa sebelum dan setelah freeze thaw tidak terjadi perubahan signifikan, selain itu juga F5 menunjukan nilai elastisitas dengan tarikan maksimum sampai film bertahan sebelum putus sehingga memenuhi semua persyaratan karakteristik serta memasuki rentang parameter dan dapat disimpulkan bahwa F5 dengan PVA 13% dan PVP K30 5% merupakan formula optimum.
Comparison of Hemoglobin A1C in Non-Diabetic PsoriasisPatients With and Without Arthritis
Authors: Conti Lucas Braga , Beckhauser Ana Paula
Published: August 2024

Introdução: A psoríase é uma dermatose comum, eritemato-escamosa causada
pela hiperplasia de queratinócitos da epiderme. Na psoríase são comuns comorbidades
como doença de Crohn, aterosclerose, hipertensão, dislipidemia,
hiper-homocisteinemia, entre outras, que potencializam os riscos cardiovasculares
e desordens metabólicas como a diabetes mellitus (DM) e síndrome
metabólica. Pacientes com psoríase podem desenvolver Artrite Psoriásica
(AP). Semelhante à psoríase puramente cutânea, a AP apresenta relação a comorbidades
como a DM2, hipertensão, obesidade, hiperlipidemia e síndrome
metabólica. Todavia não se sabe se a associação com diabetes difere nos indivíduos
com psoríase com e sem AP. Objetivos: Estudar comparativamente a
prevalência de alterações de HbA1c em indivíduos não diabéticos com psoríase,
com e sem artrite psoriásica. Metodologia: Estudo observacional transversal
1
avaliada foi de 49 paciente, sendo 23 do sexo feminino, com idades variando
de 19 a 77 anos (mediana de 53). Na análise foi possível encontrar valores
elevados de HbA1c dentro da população que apresentava quadro de artrite
associada (p=0,02) quando comaprada com os sem artrite, assim como, ela
também foi encontrada elevada em pacientes que faziam uso do medicamento
secuquinumabe (p=0,05). Nenhuma associação com atividade inflamatória
pode ser comprovada. Conclusões: Pacientes não diabéticos com artrite psoriásica
apresentaram valores de HbA1c mais elevados dos que os com psoríase
mas sem artrite. Além disso, foi observado um aumento nos níveis de HbaA1c
nos pacientes que faziam uso do medicamento secuquinumabe. Neste estudo
não foi possível demonstrar associação entre valores de HbA1c com índices de
atividade de pele (PASI), nem com índices de atividade articular (DAPSA).
Palavras-chave: Psoríase. Artrite psoriásica. Diabetes mellitus. Glicemia.
I
Treatment Adherence in Lupus Mephritis Patients is Assoiated to Mood Disorders
Authors: Crupzacki Ana Paula , Silva Thiago Alberto F/ G. da
Published: August 2024

Justificativa: Nefrite lúpica (NL) é uma complicação grave dos lúpus eritematoso
sistêmico que atinge uma baixa taxa de remissão completa. Aderência ao
tratamento é fundamental neste contexto. Objetivo: estudar a aderência ao
tratamento em pacientes com NL e sua possível associação com desordens de
humor. Método: estudo transversal com 69 pacientes com NL com aplicação
do questionário BMQ (Brief Medication Questionnaire), questionários CES-D
(Center For Epidemiological Studies- Depression) e BAI (Beck Anxiety Questionnaire).
Dados epidemiológicos foram obtidos por revisão de prontuários. Resultados:
Baixa adesão foi encontrada em 13/69 (18,8%); provavelmente baixa
adesão em 30/69 (43,3%); provável adesão em 23/69 (33,3%) e adesão em
3/69 (4,3%). Cerca de 32/69 (46,3%) dos indivíduos obtiveram pontuação positiva
no domínio “ regime” do BMQ; 26/69 (37,6%) obtiveram pontuação positiva
no domínio “crenças” e 64/69 (92,7%) obtiveram nota positiva no domínio
“lembrança”. Ansiedade (p < 0,0001) e depressão (p=0,001) estiveram associadas
a baixas taxas de adesão, mas não com variáveis epidemiológicas (todas
com p=ns). Conclusões: Há um alto grau de não adesão do tratamento entre
os pacientes da NL. Transtornos de humor estão associados negativamente à
taxa de adesão.
Descritores: Aderência a tratamento; Nefrite lúpica, Depressão, Ansiedade.
Carbohydrate Counting: What is the Evidence and how to A[[ly it in Clinical Practice
Authors: Campos Letícia Fulgante
Published: August 2024

O Diabetes Mellitus tipo 1 (DM1) é uma doença autoimune que aumenta a
morbimortalidade e reduz a qualidade de vida. O controle glicêmico adequado
é o principal objetivo para prevenir as complicações. A terapia nutricional
desempenha papel fundamental no tratamento multidisciplinar e, dentro
das estratégias, a contagem de carboidratos é um método de planejamento
nutricional dos pacientes e deve fazer parte das estratégias nutricionais para
prevenção de episódios de hipo e hiperglicemia. O “Projeto DOCE” (Diabetes
Objetivando Controle e Educação -FEMPAR, Brasil) é um serviço multidisciplinar
que visa oferecer atendimento de qualidade aos pacientes com DM1. A
contagem de carboidratos faz parte do acompanhamento desses pacientes e é
sempre feita individualmente para cada paciente, associada a outras intervenções
nutricionais. O fator insulina/carboidrato é sempre calculado de acordo
com toda a equipe multidisciplinar. As evidências apontam que a contagem de
carboidratos é uma técnica eficaz e segura para melhorar o controle glicêmico
e a qualidade de vida em pacientes com DM1. A técnica de contagem de
carboidratos tem sido adotada pelo nosso serviço de forma mais estruturada
desde julho de 2023, quando uma nutricionista passou a fazer parte da equipe
multidisciplinar, e estamos em processo de coleta de dados do nosso serviço
para avaliar e mostrar nossos resultados em uma nova publicação em breve.
Descritores: Diabetes Mellitus tipo 1, Terapia Nutricional, Contagem de Carboidratos
Evaluating the Diagnostic Accuracy of Anti-zinc Transporter 8 Antibodies inType 1 Diabetes: A Systematic Review and meta-analysis
Authors: Oliveira Luis Matos de , Rocha Roseanne Montargil
Published: August 2024

Introduction: The association between autoantibodies and the risk of type 1
diabetes mellitus (T1DM) is well established. However, there is still a lack of
quantitative insight into the role of anti-zinc transporter 8 (anti-ZnT8) antibodies
and their efficacy in T1DM diagnosis. Objective: To conduct a systematic
review and meta-analysis on the association between anti-ZnT8 autoantibodies
and the risk of T1DM. Methods: Relevant studies were retrieved from the
PubMed database and analyzed using a fixed or random-effects model. Results:
Out of 211 screened articles, 23 studies were selected and a total of
14,172 patients were included in the analysis. Our pooled analysis revealed
that anti-ZnT8 autoantibody expression was significantly associated with an
increased risk of T1DM development in both children and adults [OR 1.14 (95%
CI: 1.12-1.16)]. Conclusion: Our systematic review and meta-analysis provides
evidence supporting a significant association between anti-ZnT8 autoantibody
positivity and an increased risk of T1DM development.
Keywords: Type 1 diabetes mellitus; Zinc transporter-8; Autoantibodies; Diagnosis
Return to Play in High-level Athletes after SARS-CoV-2 Infection
Authors: S Calvache , N Muñoz
Published: August 2024

In sports medicine, the recovery process for injuries to the musculoskeletal system has been well established, including the recovery time until the athlete can compete again to prevent relapses. These decisions support the sports physician in acting with greater confidence. However, there are no clear criteria and protocols for other systemic diseases. In the following study, we report our experience and suggest an action protocol for a professional basketball team.
Bibliographic coupling of documents: An analysis of articles published in the derivative market
Authors: SUBEESH VK  , LIYA K
Published: August 2024

This article gives a bibliographic analysis of relevant publications in the area of the derivative market. The goal of this study is to scientifically assess research trends in the area of the derivative market using bibliometric analysis. Using the themes generated here, the direction for the future scope of research work has also been discussed. The data were collected from the Scopus database using specified search criteria. In this study, VOS Viewer and Microsoft Excel were used to assess co-authorship and citation patterns. To give an in-depth comprehension of the bibliographic pattern of literature in the derivative market, bibliometric coupling of documents, journals, and countries was also incorporated in this study. This is the first research to investigate the bibliometric relationships between pieces of literature in the derivative market.
Potential of Oyster Mushroom (Pleurotus ostreatus) secondary metabolites on KRAS protein in-silico liver cancer
Authors: Desy Lailatul Rachmah  , Awik Puji Dyah Nurhayati
Published: August 2024

Liver Cell Carcinoma (KSH) currently ranks as the fourth most common cause of death due to cancer worldwide and is the sixth most common cancer in the world. HCC (Hepatocellular Carcinoma) is caused by environmental factors, viral infections, and certain genetic changes. Ras is a very important oncogene and is hypermutated in various types of cancer, including HCC. The doxorubicin compound is a curative agent that is widely used for chemotherapy treatment of various types of cancer, however, administration of the kura agent with high cytotoxic activity can cause several side effects. Secondary metabolite compounds have anti-oxidant capabilities including breaking free radical chains and chelating redox-active metal ions which cause lipid peroxidation. These properties also help prevent cancer. Pleurotus otstreatus bioactive compounds that have antioxidant potential, flavonol. Due to the potential cytotoxic activity of these secondary metabolites, a bioinformatics approach is needed in this research to determine the results of predicting the interaction activity of flavonol compounds on the KRAS protein in silico and to determine the amino acids and bonds involved in the interaction. between these compounds and the KRAS protein, as a reference for future HCC drugs. The method used is using the PyRx device, Biovia Discovery Studio, Autodock for the docking process and validating the docking results. The results of this research are that flavonol compounds have a docking value of -7.1 kcal/mol. This compound has the potential as a candidate compound that can be used in liver cancer therapy, because it’s have high values ​​and close to the positive control value, namely doxorubicin, of -7.6 kcal/mol.
LOGISTIC AND PROBIT REGRESSION MODELING TO PREDICT THE OPPORTUNITIES OF DIABETES IN PROSPECTIVE ATHLETES
Authors: Ariyanto Danang , Sofro A'yunin , Hanifah A’idah Nur , Prihanto Junaidi Budi , Maulana Dimas Avian , Romadhonia Riska Wahyu
Published: August 2024

Diabetes is among the most prevalent chronic diseases globally, posing significant health risks to individuals. The identification of individuals at risk of developing these conditions is of paramount importance, particularly in high-stress and physically demanding activities such as athletic training. To find out the chances of a prospective athlete suffering from diabetes or not, models for binary data can be used, including logistic regression and probit models. The data used is primary data from prospective athletes in East Java, including prospective athletes from the State University of Surabaya and East Java Koni Athletes. This study aimed to develop an early prediction model for diabetes in prospective athletic candidates using a bivariate logistic and probit regression approach while considering the influence of socio-demographic and anthropometric factors. To selecting the best model between logistic regression and probit regression using Akaike’s Information Criterion (AIC) value, the smaller the AIC value gets means that the model is closer to the actual value or being the best model. Logistic regression has a smaller AIC value (129,85) than probit regression, this means that the logistic model is the best model. In this paper, an attempt is made to explore the use of logistic and probit regression to determine the factors which significantly influence the diabetes disease and we got that the logistic model as the best model because it has a smaller AIC value than the probit model. Based on the result of analysis and discussion, it can be concluded that there are two factors called mother’s job and finance which are influenced to the response variable, diabetes disease at significance level of 5%.
OPTIMIZATION OF WASTE MANAGEMENT IN SUMBAWA DISTRICT USING A DYNAMIC SYSTEM MODEL
Authors: Susilawati Tri , Darmawan Indra , Alfaresa Muhammad Saiful
Published: August 2024

The main problem that occurs in society today apart from basic needs is the problem of waste. This waste problem certainly needs a solution in good, effective, sustainable and long-term management. The waste issue not only occur in big cities but also in developing areas. Sumbawa Regency as one of the regions that continues to develop and grow requires optimum and long-term planning of solid waste management and systems. In 2021, the waste handled in Sumbawa Regency will only be around 17.5% of the total waste. This shows that the waste management system in Sumbawa Regency is not optimal. Optimal waste management can be achieved by taking an academic approach through model development. One such model is the dynamic system model. This can describe the causal relationship between variables that affect solid waste problems and to provide an overview of the waste management system through simulations based on the factors that influence the processing model. Therefore, it is necessary to develop an optimization model for waste management specifically in Sumbawa Regency using a dynamic systems approach. The purpose of this study is to describe waste management in the form of an optimization model for waste management in Sumbawa Regency with a dynamic system. Optimization results show that the optimistic model yields a total of 127.01 tons/day, the moderate model yields a total of 98.23 tons/day and the pessimistic model produces 62.5 tons/day
ECONOMIC GLOBALIZATION, ECONOMIC GROWTH, AND HUMAN CAPITAL : EMPIRICAL EVIDENCE USING THREE STAGE LEAST SQUARE IN INDONESIA
Authors: Huda Qorinul , Istiana Nofita
Published: August 2024

The pace of globalization is increasing rapidly and dynamically as time goes by. Indonesia, located takes advantage of globalization to encourage economic growth. However, over the last decade, from 2000 to 2019, Indonesia's economic globalization index has tended to decline along with the increase in the global economic globalization index. Indonesia's economic growth has been relatively stagnant. Human capital, as the primary input in Indonesia's economic system, is suspected to be suboptimal. In the National Medium-Term Development Plan (RPJMN) for 2020-2024, economic growth and human capital are the main focus in achieving national prosperity. Human capital in this study uses health indicators as a proxy for assessing productivity and educational investment approaches. Data is transformed to meet the stationarity requirements of time series data. The study employs the Three Stage Least Square (3SLS) simultaneous equation method to examine total and direct effects. The estimation results show that changes in globalization growth are directly influenced by changes in economic growth, exchange rate growth, and inflation. Changes in economic growth are directly influenced by changes in exchange rate growth, globalization index growth, and inflation. Human capital is directly influenced by changes in globalization index growth, changes in economic growth, inflation, previous-year inflation, and changes in unemployment rates
PLS-SEM ANALYSIS OF SOCIAL ENVIRONMENT'S IMPACT ON MATHEMATICS DIGITAL LITERACY
Authors: Purwanto Arie , Rusmining Rusmining
Published: August 2024

The rapid development of technology makes us have to be able to adapt well. Using the internet as a medium for activities is an unavoidable part. Therefore, it is necessary to learn about the ability to use the internet in activities called digital literacy. Digital literacy is a basic skill that students must have. It is no exception in the field of mathematics as one of the absolute sciences taught at every level of education. Therefore, researchers are interested in examining digital literacy in the field of mathematics. This research in general is still very rarely done, therefore it requires an in-depth understanding of theoretical studies to see the factors that influence digital literacy skills in the field of mathematics. The lack of sample size and the relativity of adequacy in fulfilling assumptions encourage the use of PLS-SEM as an alternative in analyzing the model formed. In this study, Explanatory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) are still used to build a framework and test the structural model to be formed. In addition, the method used gives researchers the freedom to express curiosity about the problem at hand. The results obtained show that the final model can be said to be good. Mathematics digital literacy skills are influenced by several main variables that are interrelated. These variables start from the carrying capacity of schools and families. These two variables will then have an impact on the readiness of teachers and students in the community to succeed or support mathematics digital literacy skills. School readiness and family support are the main keys in succeeding or improving digital math literacy skills.
ANALYSIS OF RESOLVING EFFICIENT DOMINATING SET AND ITS APPLICATION SCHEME IN SOLVING ETLE PROBLEMS
Authors: Prihandini R M , Rahmadani M R , Dafik Dafik
Published: August 2024

This research focuses on the analysis of Resolving Efficient Dominating Set (REDS) and its application in solving Electronic Traffic Law Enforcement (ETLE) problems using the Spatial Temporal Graph Neural Network (STGNN). Resolving Efficient Dominating Set (REDS) is a concept in graph theory that studies a set of points in a graph that efficiently monitors other points. It involves ensuring that each point v ∈ V (G) - D is dominated by exactly one point in D, with no adjacent points in D, and the representation of point v ∈ V (G) concerning D is not the same, which is termed as a resolving efficient dominating set.  In the context of Electronic Traffic Law Enforcement (ETLE), the analysis of REDS has a significant impact. The theorem resulting from the analysis of REDS enables the determination of the number of traffic violation sensors required. Furthermore, by taking simulation data from road points, violation forecasting can be performed. The accurate predictions from this forecasting can assist authorities in anticipating and addressing traffic violation issues more effectively.
ALGORITHM FOR CONSTRUCTING TRIPLE IDENTITY GRAPH OF RING Z_n USING PYTHON
Authors: Kurniawan Vika Yugi , Ekasiwi Chessa Fanny
Published: August 2024

Let R be a commutative ring. The triple identity graph of ring R is denoted by TE(R) with sets of vertices  Two different vertices  and  are adjacent if and only if there is an element  in  such that  and . To easily visualize the triple identity graph, a program is needed to represent it briefly. Python can easily manipulate, analyze, and visualize data. Therefore, this study uses Python to construct the algorithm for  In this research, some examples will be given and then be observed for new characteristics of the triple identity graph of ring  such as the connectedness, the diameter, and the girth. And we find the characterize  for which graph  is empty, connected, or Hamiltonian.
THE NUMERICAL APPROXIMATION OF STATIONARY WAVE SOLUTIONS FOR TWO-COMPONENT SYSTEM OF NONLINEAR SCHRÖDINGER EQUATIONS BY USING GENERALIZATION PETVIASHVILI METHOD
Authors: Robbaniyyah Nuzla Af’idatur , Chern Jann-Long , Abdurahim Abdurahim
Published: August 2024

The Petviashvili method is a numerical method for obtaining fundamental solitary wave solutions of stationary scalar nonlinear wave equations with power-law nonlinearity: , where  is a positive definite and self-adjoint operator and  is constant. Due to the case being a system of solitary nonlinear wave equations, we generalize the Petviashvili method. We apply this generalized method for a two-component system of Nonlinear Schr dinger Equations (NLSE) for 2-D.
SPATIAL REGRESSION APPROACH TO MODELLING POVERTY IN JAVA ISLAND 2022
Authors: Siallagan Maria A. Hasiholan , Pusponegoro Novi Hidayat
Published: August 2024

Geographically Weighted Regression (GWR) model is a powerful tool for analyzing spatial patterns in data. However, the standard form of a spatial model that uses a single bandwidth calibration may be unrealistic because the response-predictor relationship may be either linear or nonlinear. To address this issue, the Multiscale GWR (MSGWR) model offers improved model performance by employing Generalized Additive Model (GAM) with varying bandwidth or smoothing function for each covariate in the model.  This research aims to analyze the Percentage of Poor Population (PPP) on Java Island in 2022 using the geospatial models and related socioeconomic and demographic attributes, such as Open Unemployment Rate, Human Development Index, Labor Force Participation Rate, and GRDP Per capita to identify the best model in explaining the spatial pattern and to find out the determinant of PPP on Java Island in 2022. This study uses secondary data from Statistics Indonesia. The findings reveal that the MSGWR model provides the highest R2 and smallest AICc value compared to single bandwidth models, specifically the GWR and MXGWR models. Furthermore, the MSGWR model indicates that HDI has a significant negative effect on PPP, whereas LFPR has a significant positive effect on PPP across all districts in Java Island in 2022.
VALUE AT RISK ESTIMATION FOR STOCK PORTFOLIO USING THE ARCHIMEDEAN COPULA APPROACH
Authors: Saifullah Mohammad Dicky , Sa'adah Umu , Andawaningtyas Kwardiniya , Handamari Endang Wahyu
Published: August 2024

Investment is one of the many ways to achieve future profits. One form of investment that is widely made is stocks. The return obtained in investing in stocks is potentially higher than other investment alternatives, but the risks borne are amplified, so it is necessary to analyze these risks that may occur. In this study, the Archimedean copula method is used to estimate the Value at Risk on shares of PT Bank Rakyat Indonesia Tbk (BBRI) and PT Telekomunikasi Indonesia Tbk (TLKM) for the period September 1, 2021, to August 31, 2023. The stock data is used to determine the Archimedean copula model and calculate the estimated value of Value at Risk (VaR) on the stock return portfolio using the Archimedean copula approach. The Archimedean copula models used are the Clayton copula model, Gumbel copula, and Frank copula. Of the three Archimedean copula models, the best model was selected by looking at the largest Maximum Likelihood Estimation (MLE) value. In this study, the log-likelihood value of Clayton copula is 7.958, Gumbel copula is 6.663, and Frank copula is 8.398. Therefore, Frank copula is the best Archimedean copula model with the largest log-likelihood value of 8.398 for the said data. Then the VaR estimation is done with the Frank copula model. The Value at Risk estimation results based on the Frank copula model show maximum loss rates of -0.0277 at the 90% confidence level, -0.0363 at the 95% confidence level, and -0.0516 at the 99% confidence level.