bluuebunny/crossref_metadata_2025 huggingface dataset:
“Caríssimo Papa”:
Authors: Costa Marcelo Timotheo da
Published: February 2025

Em 1980, o papa João Paulo II visitou o Brasil pela primeira vez. A extensa programação pontifícia incluiu encontro do papa com o operariado brasileiro, no estádio do Morumbi, São Paulo. Ali, Karol Wojtyla foi saudado por Waldemar Rossi, liderança operária leiga da arquidiocese paulistana. Rossi redigiu discurso bastante crítico em relação à condição dos trabalhadores nacionais e também quanto à situação política então vigente. Discurso esse que teria sido encurtado por razões ainda obscuras. No presente artigo, propõe-se que tal episódio revela a tensão que cercou a visita papal. Tensão presente na praça pública brasileira, com o país vivenciando sua mais longa ditadura, bem como no interior do catolicismo nacional, por conta de polêmicas teológicas e pastorais. Assim, quer-se analisar texto integral e contexto do discurso escrito por Rossi e as possíveis implicações de seu parcial silenciamento, episódio pouco debatido até agora.
Evangelhos Apócrifos Gregos e latinos
Authors: Funari Pedro Paulo Abreu
Published: February 2025

Resenha.
Da Plaza Mayor à Plaza de Armas de Villahermosa, México
Authors: Torre Jorge Herrera de la , Silva Natália Achcar Monteiro , Safe Simone Marques de Sousa
Published: February 2025

Este artigo pretende analisar a evolução urbana da região morfológica do coração histórico de Villahermosa, México a partir dos métodos da Escola Inglesa de Morfologia Urbana e da Memória Oral. O objetivo é compreender a identidade do lugar, cuja historicidade tem sido amplamente questionada, contribuindo à sua valoração e valorização patrimonial. Os resultados apresentam cronologicamente os períodos morfológicos da Plaza de Armas através de uma breve abordagem histórica e paisagística, acompanhada de mapeamentos de épocas construtivas e do uso do solo, demonstrando como os processos histórico-políticos têm influenciado na autenticidade e integridade do espaço primogênito da cidade.
Reabilitação de bacia de detenção em Belo Horizonte/MG
Authors: Cunha Marcela Silveira Rodrigues da , Zyngier Camila , Silva Natália Achcar Monteiro
Published: February 2025

Esse estudo propõe a análise socioambiental da evolução urbana no entorno da bacia do córrego Brejo do Quaresma na regional de Venda Nova em Belo Horizonte/MG. Em termos metodológicos, foram aplicados os fundamentos da Escola Inglesa de Morfologia Urbana e a memória oral, no intuito de compreender o processo de ocupação urbana da área e os impactos físicos, ambientais e sociais ocasionados ao longo do tempo. Em termos de técnicas de pesquisas, realizou-se revisão bibliográfica e produção de mapeamentos. Os resultados apresentam diretrizes projetuais baseadas, principalmente, nos conceitos de infraestrutura verde, e políticas públicas colaborativas relacionadas às práticas socioambientais que podem incentivar e resgatar os valores identitários dos moradores de Venda Nova.
Bacia Hidrográfica Água Espraiada - potencial para IVA
Authors: Gundim Laura Soares , Silva Natália Achcar Monteiro , Pinheiro Cristiane Borda , Pinheiro Rafael Lemieszek
Published: February 2025

O objeto de estudo deste artigo é a bacia hidrográfica Água Espraiada em São Paulo/SP enquanto potencial unidade de planejamento de Infraestrutura Verde-Azul. Objetivou-se demonstrar possibilidades de integração entre corpos hídricos e áreas verdes em um ambiente urbano densamente construído. Foi realizada revisão de literatura e legislação, análise e produção de mapas e definição de diretrizes multiescalares que resultaram no aumento de áreas naturalmente permeáveis de 2,21% para 35,00%.
Krieg und Komödie
Authors: Stammen Silvia
Published: February 2025

In München zeigen die Kammerspiele «proteus 2481 von Aischylos bzw. Thomas Köck – ein Satyrspiel» und das Residenztheater den Doppelabend «Die Gewehre der Frau Carrar» von Bertolt Brecht / «Würgendes Blei» von Björn SC Deigner

Von Silvia Stammen
Das Stottern im System
Authors: Kralicek Wolfgang
Published: February 2025

In «Ever Given» verbindet Helgard Haug (Rimini Protokoll) den Stau im Suezkanal mit individuellen Biografien, in denen etwas klemmt

Von Wolfgang Kralicek
«Der Körper ist schneller als der Kopf»
Authors: Hoger Hannelore
Published: February 2025

Statt eines Nachrufs: Hannelore Hoger spricht über ihre Arbeit am Theater – ein Text aus dem Jahr 1988
Psychische Störungen: Gesundheitsökonomische Eckdaten und Dunkelfelder
Authors: Kuhn Joseph
Published: February 2025

Der Gesetzentwurf der gescheiterten Ampel-Koalition zur Stärkung der öffentlichen Gesundheit hat für die gesamte kontinuierliche systematische Beobachtung, Analyse, Interpretation und Berichterstattung von Gesundheitsdaten nichtübertragbarer Krankheiten, einschließlich der psychischen Störungen 750.000 Euro jährlich vorgesehen. 100 Meter Autobahnbau kosten mehr. Gesundheitswissenschaftler Dr., Dipl.-Psych. Joseph Kuhn diskutiert dieses Missverhältnis und erörtert Entwicklungspotentiale der Behandlung psychischer Störungen mit Blick auf die von Hartmut Reiners geprägte „ökonomische Vernunft der Solidarität“ für die sozialstaatliche Organisation der Versorgung.
Wir müssen die Innovationskraft unseres überregulierten Gesundheitswesens entfesseln – Plädoyer für einen Politikwechsel
Authors: Gass Gerald
Published: February 2025

Während die gesamten Jahrgänge der Baby-Boomer bis zum Jahr 2040 erheblich mehr Versorgung im Krankenhaus und Pflegeheim benötigen, werden nie mehr so viele Menschen im deutschen Gesundheitswesen arbeiten wie heute. Dr. Gerald Gass, Vorstandsvorsitzender der Deutschen Krankenhausgesellschaft, skizziert das erforderliche neue Denken und plädiert für einen entschlossenen Politikwechsel.
Von Antinomien der Ökonomie und dem Privaten im Gesundheitswesen
Authors: Gibis Bernhard
Published: February 2025

Nach vielen Debatten im Zwiebelfisch, Feiern und anderen Zusammentreffen mit dem Jubilar freue mich über die Einladung, die zurückliegenden Diskussionen, Entwicklungen und Auseinandersetzungen zu den Irrungen und Wirrungen gesundheitspolitischen und -ökonomischen Denkens in einem Beitrag Revue passieren zu lassen.
Werner Heldt (1904–1954)
Authors: Hein Verena
Published: February 2025

„Ich bin in einer großen, grauen Stadt geboren, / Wo ewig Regen in ein Meer von Dächern fällt; / Und ihre Grenzen sind am Horizont verloren: / Die graue Stadt ist meine Heimat, meine Welt.“ Werner Heldts Gedicht Heimat aus dem Jahr 1932 steht als Leitsatz für sein gesamtes Oeuvre. Es behandelt sein Lebensthema, die Stadt Berlin, und ruft Stimmungsbilder vor: Angst und Einsamkeit und das Gefühl von tiefer Melancholie. Vorliegender Band stellt das Leben und die künstlerische Entwicklung des Berliner Malers (1904–1954) vor. Während des Nationalsozialismus gelang es Heldt, sich der Inbesitznahme der Kunst durch die Nationalsozialisten subtil zu verwehren. Im Nachkriegsdeutschland war er nicht nur mit Niederlage, kollektiver Schuld und der „Unfähigkeit zu trauern“ konfrontiert, sondern auch mit der Zerstörung der Städte, die als Mahnmal für persönliches Leid und Verlust allgegenwärtig waren. Werner Heldt entwickelte das tröstende Sinnbild „Berlin am Meer“, eine Bildfindung, die aus der zeitgenössischen Bildproduktion herausragt. Seine künstlerische Leistung erscheint noch 60 Jahre nach seinem Tod zeitlos gültig und belegt seine exponierte Stellung in der deutschen Nachkriegskunst.

 

Biographische Informationen

Verena Hein (geb. 1979), Studium der Kunstgeschichte, Theaterwissenschaft und Kommunikationswissenschaft an der Ludwig-Maximilians-Universität München. Seit 2012 Kuratorin und Leitung der Ausstellungsabteilung im Museum Villa Stuck, München, zahlreiche Ausstellungsprojekte und Veröffentlichungen.

 

Reihe

Kunstwissenschaften - Band 26
Werteorientierte Führung in der Wirtschaft
Authors: Siara Iris
Published: February 2025

Moralische Werte und Tugenden geraten im Arbeitsalltag angesichts von Leistungsdruck, Konkurrenzkampf und Karrierebestrebungen nicht selten aus dem Blickfeld. Das Erreichen von Quartalszielen und eine über alle Wirtschaftszweige hinweg stark quantitativ ausgelegte Leistungsbewertung führen zu Einseitigkeiten und der Notwendigkeit, die Frage nach einer Führungsethik in der Wirtschaft immer wieder neu zu stellen.

In diesem Buch wird die Vielfalt der führungsethischen Konzepte in einer interdisziplinären Sondierung vorgestellt und eine pragmatische Typologie von wirtschaftsethischen Ansätzen, tugendethischen Vorschlägen sowie biblischen und christlich-spirituellen Entwürfen entwickelt. Diese Typologie dient zur theoretischen Orientierung sowie zur werteorientierten Identitäts- und Persönlichkeitsentwicklung von Führungskräften in der Berufspraxis. Ergänzend werden Vorschläge für ein strukturelles Ethikmanagement thematisiert, darunter Wertekodizes, Wertekommissionen und Wertecoachings.

 

Biographische Informationen

Iris Siara studierte Katholische Theologie an der Ludwig-Maximilians-Universität in München und an der University of Alberta in Edmonton. Sie promovierte im Fach Theologische Ethik und ist seit 2010 in der Wirtschaft in den Bereichen Human Resources und Corporate Social Responsibility tätig.

 

Reihe

Wirtschafts- und Sozialwissenschaften - Band 52
Zeitmanagement im Unternehmenssetup Südafrika
Authors: Miller Barbara
Published: February 2025

In ihrer Dissertation fokussiert die Autorin die berufliche Interaktion innerhalb der heterogenen Angestelltenstruktur Südafrikas und beantwortet die Frage, inwieweit sich das unterschiedliche Zeitverständnis der Mitarbeiter auf ihre Zusammenarbeit auswirkt. Dabei erhält sie Antworten auf die Fragen nach der Bedeutung des Zeitmanagements für die erfolgreiche Gestaltung interkultureller Zusammenarbeit und dem Weiterbildungsbedarf der Angestellten. Der Erkenntnisgewinn dieser Arbeit ist daher sowohl für Bildungsinstitutionen und Manager im südafrikanischen Unternehmenssetup interessant als auch für Unternehmen, die in Südafrika expandieren wollen.

 

Biographische Informationen

Als Expertin für Managementweiterbildung und Persönlichkeitsentwicklung führt Frau Barbara Miller, Geschäftsführerin der Unternehmensberatung für Kommunikation Cmillers, erfolgreich Workshops und Coachings für Fach- und Führungskräfte durch. Als studierte Psycholinguistin berät sie zu Führungskompetenzen, Themen der persönlichen Ausstrahlung, dem professionellen Auftreten sowie der Psychologie der kommunikativen Interaktion. Ihre langjährige Berufserfahrung im Gesundheitswesen, in der freien Wirtschaft und der Erwachsenenbildung prägt ihr gutes Gespür für den Menschen und dessen individuelle Perspektive zur persönlichen und beruflichen Weiterentwicklung.

 

Reihe

Münchner Beiträge zur Bildungsforschung - Band 34
Mediale Öffentlichkeit als Strafzumessungskriterium
Authors: Beyersdorf Caroline
Published: February 2025

Das Werk befasst sich mit dem Verhältnis von Medienöffentlichkeit und Strafverfahren und geht dabei der Frage nach, wie persönlichkeitsrechtsverletzende Medienberichterstattung im Rahmen eines Strafverfahrens rechtlich zu qualifizieren ist und wie diese in der Folge im Rahmen des Strafverfahrens zu einem gerechten Ausgleich für die Betroffenen gebracht werden kann. Auf dem Lösungsweg werden insbesondere auch empirische Studien, unter anderem aus dem Bereich der Kommunikationswissenschaft, dargestellt und hinsichtlich ihrer Bedeutung für die Frage der rechtlichen Behandlung persönlichkeitsrechtsverletzender Medienberichterstattung im Strafverfahren ausgewertet. Das dabei aufgeworfene Bild des Spannungsverhältnisses zwischen Medienöffentlichkeit und Strafverfahren verdeutlicht die Bedeutung der dieser Arbeit zugrundeliegenden Fragestellung in einer modernen Welt.

 

Biographische Informationen

Nach Studium, Referendariat und Promotion in München ist die Autorin seit 2020 als Rechtsanwältin bei einer führenden Wirtschaftskanzlei in München tätig.

 

Reihe

Rechtswissenschaftliche Forschung und Entwicklung - Band 845
ANALYSIS OF PROMISING DEVICES FOR ACCUMULATION OF ENERGY OF WORKING FLUID IN HYDRAULIC DRIVES OF TRANSPORT AND TECHNOLOGICAL MACHINES
Authors: Savinkov M. , Posmetev Valeriy , Nikonov Vadim , Hrapov I.
Published: February 2025

The relevance of using pneumohydraulic accumulators in hydropneumatic systems of transport and technological machines is substantiated. The design features, operation and limitations in the use of traditional piston-type pneumohydraulic accumulators are described. The analysis of existing designs of hydropneumatic systems for storing and recuperating the energy of the working fluid is performed. Based on the identified shortcomings in the operation of such systems, the authors propose a promising scheme of a pneumohydraulic accumulating device that ensures increased efficiency of the hydraulic technological equipment of transport and technological machines.
INFLUENCE OF FOREST SHELTER BELTS ON CARBON DIOXIDE EMISSIONS IN KAMENNAYA STEPPE CONDITIONS
Authors: Bahtin Andrey
Published: February 2025

In this paper, the influence of a protective forest strip on carbon dioxide emissions in the territory of the Kamennaya Steppe State Nature Reserve is investigated. Studies of carbon dioxide emissions were carried out using the closed chamber method using a portable soil gas exchange measurement system LI-870SC (CO2/H2O). The average carbon emissions in the area of protective forest strips are about 1.4 times higher than in arable soils. It is obvious that protective forest stands are actively involved in regulating the carbon balance of the ecosystem not only by absorbing carbon dioxide during photosynthesis, but also contribute to an increase in CO2 emissions from chernozems.
EVALUATION OF THE EFFECT OF ALKALINE COLLAGEN HYDROLYSATE ON THE BIOMETRIC PARAMETERS OF THE PLANT
Authors: Bryndina L. , Korchagina Anna , Repnikova L
Published: February 2025

The article examines the effect of alkaline collagen hydrolysate on biometric indicators of plant growth. Collagen, which contains a large number of amino acids, is of limited use due to its high molecular weight and low solubility in water, which makes it difficult for the plant to absorb it. However, the hydrolysis of the polymer makes it possible to obtain smaller polypeptides that can be used by plants. The study showed that plants treated with a fertilizer based on collagen hydrolysate have developed leaf plates in which photosynthesis is more active, which, in turn, affects the regeneration of adventitious roots. It has been experimentally established that a polypeptide of animal origin has a positive effect on the development of leaf plates and root formation as early as day 15. It is recommended to use 10% collagen with 1% NaOH solution in a 1:1 ratio to achieve optimal results.
CLIMATIC AND SPATIAL ORGANIZATION OF RUSSIAN ORTHODOX MONASTERIES
Authors: Varguzina M. , Bugakova Anna
Published: February 2025

The article examines the climatic and spatial organization of Russian Orthodox monasteries, their adaptation to natural and climatic conditions, as well as the influence of these factors on architectural and spatial planning. Attention is paid to how monasteries were built taking into account the peculiarities of the local climate in order to create comfortable conditions for the life of monks and the implementation of religious practices. The study highlights the role of the natural environment not only in the practical, but also in the spiritual aspect of monastic life, reflecting the monks' desire for harmony with nature.
ECOSYSTEM SERVICES OF URBAN GREEN SPACES
Authors: Staruhina Ekaterina
Published: February 2025

The topic of ecosystem services of urban green spaces is becoming increasingly relevant in the context of the rapid growth of urbanization and environmental challenges faced by modern cities. The increase in population density and the expansion of urban areas create a great burden on natural resources, worsening the environmental situation in cities. Urban forests, being an essential part of the ecological infrastructure, provide a number of ecosystem services that contribute to improving the quality of life, reducing air pollution, regulating the microclimate, maintaining biodiversity and creating recreational areas for citizens.
The article analyzes modern research on ecosystem services of urban forests and their impact on sustainable urban development. Quantitative and qualitative methods were used for the analysis, including GIS analysis to assess the distribution of green spaces. The results show that Urban forests have a significant impact on temperature reduction, air filtration and the provision of recreation areas, but the need for these services exceeds their current supply. The need to strengthen measures to protect and increase the area of green areas to meet the growing demand has been identified. Sustainable management of urban forests and the integration of ecosystem services into urban planning policies will help improve the quality of life of the population and reduce the negative effects of urbanization.
COMPARATIVE ANALYSIS OF THE CONDITION OF EUROPEAN PALLIDA LINDEN SPECIMENS GROWING IN DIFFERENT TERRITORIES OF THE CENTRAL FOREST-STEPPE (USING THE EXAMPLE OF RAMON VILLAGE, VORONEZH REGION AND STARY OSKOL, BELGOROD REGION)
Authors: Ryazantseva O. , Tseplyaev Aleksey
Published: February 2025

The purpose of this work is the introduction results assessment of the European linden (Tilia x europaea) ‘Pallida’ planted in the Ramon village of the Voronezh region and Stary Oskol, Belgorod region, which were previously grown in nurseries in Belgium and Germany and in adulthood (8-12years old) transplanted to the conditions of a more severe climate in these areas. The plantings were assessed visually during route surveys based on the condition of the crown and leaf damage. The observations were carried out in September 2023 and September 2024. According to the results of the survey and the condition index calculation, developed by V.A. Alekseev, it was found that the plantations located in the village of Ramon, Voronezh region, are classified as "Healthy", the plantations located in Stary Oskol, Belgorod region, are classified as "Healthy with signs of weakening". According to the assessment of the introduction success in accordance with the Lapin P.I. methodology, the European linden (Tilia x europaea) ‘Pallida’ is classified as agroup of quite promising introducers. At the stage of analyzing the morphometric indicators of seeds, specimens planted in the Ramon village of the Voronezh region show the best indicators close to the value of a similar species in the zone of natural growth. At the same time, the indicators of specimens growing in Stary Oskol, Belgorod region, are significantly lower.
CHANGES IN THE MORPHOMETRIC PARAMETERS OF PLANTS UNDER THE ACTION OF FERTILIZERS FROM ORGANIC WASTE
Authors: Bryndina L. , Korchagina Anna , Zhivitchenko D
Published: February 2025

The article considers the possibility of using waste from the fat and oil industry as a raw material for the production of biofertilizer. It is proposed to enrich the husk with sewage sludge.
According to the results of the study, it was found that under the influence of using a mixture based on husk and sewage sludge, positive morphometric changes are observed in plants. Fertilizers from these components in a ratio of 1:1 showed high efficiency when applied to the soil at a concentration of 10%.
SIMULATION OF THE WORKING PROCESS OF A SCREW-ROTOR FOREST FIRE GROUNDER
Authors: Zlenko Andrey
Published: February 2025

A mathematical model and solution results are presented to substantiate the effective parameters of the auger working element of a forest fire soil thrower.
INFLUENCE OF DYNAMIC LOADS ON THE STABILITY OF A MANIPULATOR TYPE TIMBER TRANSPORT MACHINE
Authors: Popikov S.
Published: February 2025

The analysis of literary sources is carried out. A mathematical model of the working process of a hydraulic manipulator of a timber transport machine when working on a slope during an emergency dumping of cargo is presented.
Применение механизма государственных закупок инноваций в контексте задач обеспечения экономической безопасности
Authors: Кириллова Е.А. , Дли М.И. , Малевич Е.П. , Масютин С.А.
Published: February 2025

целью исследования является анализ возможностей применения механизма государственных закупок инноваций в контексте современных задач обеспечения экономической безопасности государства. Методы: в качестве методов в представленном исследовании используются методы анализа, выявления причинно-следственных закономерностей, оценки возможностей реализации, эктреполяции. Результаты (Findings): в исследовании рассмотрены особенности и возможности применения механизма государственных закупок инновационной продукции в контексте задач обеспечения экономической безопасности государства. Представлено схематическое отображение его реализации как инструмента формирования ориентиров, задания ограничений и придания направленности функционирования производственно-хозяйственной системы государства, поддержки социально значимых областей и обеспечения устойчивого развития. Выводы: на основе представленной в ходе исследования оценки специфики реализации инновационных процессов в современных произвосдтвенно-хозяйственных ситсемах и изменениях внешней среды описаны возможности применения механизма государственной закупки иннноваций в российской практике.

the purpose of the study is to analyze the possibilities of using the mechanism of public procurement of innovations in the context of modern tasks of ensuring the economic security of the state. Methods: as methods in the presented study, methods of analysis, identification of cause-and-effect patterns, assessment of implementation possibilities, and extrapolation are used. Findings: the study examines the features and possibilities of using the mechanism of public procurement of innovative products in the context of the tasks of ensuring the economic security of the state. A schematic representation of its implementation is presented as a tool for forming guidelines, setting limits and giving direction to the functioning of the production and economic system of the state, supporting socially significant areas and ensuring sustainable development. Conclusions: based on the assessment of the specifics of the implementation of innovative processes in modern industrial and economic systems and changes in the external environment presented in the course of the study, the possibilities of using the mechanism of public procurement of innovations in Russian practice are described.
Regular Detection and Intelligent Monitoring Technology of Atmospheric Storage Tank Based on Acoustic Emission and Internet of Things
Authors:   Qingcheng AE Institute (Guangzhou) Co., Ltd, Xie Jiehui ,   Qingcheng AE Institute (Guangzhou) Co., Ltd, Lu Xueying
Published: February 2025

Acoustic emission testing is a non-destructive testing method that can

evaluate the corrosion status and structural integrity of storage tanks in real time. This

paper introduces the principle of acoustic emission detection, sensor installation,

system calibration and data acquisition, focuses on the application of acoustic

emission technology in the detection of tank bottom corrosion and leakage, and

compares the advantages and disadvantages of other detection technologies, and

proposes an intelligent unattended acoustic emission tank monitoring system based

on the Internet of Things. Through the integration of intelligent acoustic wave

(acoustic emission) collector, networking communication, cloud platform/server and

customer terminal, the long-term online monitoring of storage tanks is realized, the

detection efficiency and accuracy are improved, and the manual intervention and

maintenance costs are reduced.
Antibiotic potentiating activity of Casearia javitensis Kunth (Salicaceae)
Authors: Silva José Thyálisson da Costa , Costa Adrielle Rodrigues , Freitas Damiana Gonçalves de Sousa , Teixeira Guilherme Fernandes , Cordeiro Paula Patrícia Marques , Silva Maria Érika de Oliveira , de Souza Dieferson Leandro , Ribeiro Daiany Alves , Borges João Arthur de Oliveira , de Sousa Severino Denicio Gonçalves , Tampelini Flávio Silva , Mendes Rafael de Carvalho , Novais Maria Hellena Garcia , Pereira-de-Morais Luís , da Silva Sabrina Bezerra , Moura Talysson Felismino , Coutinho Henrique Douglas Melo , Almeida-Bezerra José Weverton
Published: February 2025

Antimicrobial resistance is a global concern, affecting public health and generating economic and social impacts, which
requires global strategies to contain its spread and reduce associated deaths. Medicinal plants demonstrate efficacy
against pathogenic microorganisms, offering alternatives in the fight against microbial resistance. As a highlight,
Casearia javitensis has antimicrobial and antiparasitic properties of therapeutic relevance to cope with these
microorganisms. This research aimed to evaluate the antibacterial activity of ethanolic extract of C. javitensis leaves
(EECJ), as well as its antibiotic potentiating activity. Leaves of the species were collected, dried, crushed and subjected to
extraction using ethanol. For the antimicrobial assays, conventional and multidrug-resistant bacterial (MDR) strains
were used. The inhibition capacity was analyzed by means of the Minimum Inhibitory Concentration (MIC), at
concentrations from 0.5 to 512 μg/mL. The potentiating activity was evaluated using subinhibitory concentrations of
EECJ (MIC/8) in association with the antibiotic’s gentamicin, ampicillin and norfloxacin. The data obtained was
submitted to statistical analysis. The results indicated that EECJ did not present isolated antibacterial activity (MIC >
512 μg/mL); however, it has been shown to be effective as an antibiotic enhancer, reducing the MIC of gentamicin,
ampicillin, and norfloxacin against the MDR strains of E. coli, S. aureus, and P. aeruginosa. These findings suggest that
ethanolic extract of C. javitensis may be a promising alternative in combination therapies.
A THEORETICAL UNDERSTANDING OF SINO-INDIAN STRATEGIC COMPETITION IN SOUTH ASIA
Authors: Uddin M Jashim
Published: February 2025

The rivalry between China and India is one of South Asia’s most significant geopolitical dynamics, shaping the region’s political, economic, and security landscapes. The China-India rivalry dates back to historical territorial disputes, notably the 1962 Sino-Indian War, which left a legacy of mistrust and competition. The rivalry extends to economic and strategic domains, with both nations vying for South Asian influence. The long-standing border dispute between these countries has further intensified tensions. This ongoing competition manifests in various areas, including infrastructure development, trade, and military presence, impacting the broader regional dynamics. This competition, rooted in historical disputes and contemporary strategic interests, also has significant implications for neighbouring countries. Given the context, this study explores the underlying causes of the hostility between the two Asian powers and the prospects of their relations. It analyses the relationship between China and India in the light of the ‘Balance of Threats’ theory in international politics to understand their strategic behaviour and alliance formation.
Conflicto en el Instituto Rubio de Madrid (1912). ¿Enfermeras internas o Hijas de la Caridad?
Authors: Herrera Rodríguez Francisco , González Iglesias María Elena
Published: February 2025

En junio de 1912, en el Instituto Rubio de Madrid, en cuyo seno se encontraba la Escuela de Enfermeras de Santa Isabel de Hungría, ambas instituciones fundadas por Federico Rubio y Galí (1827-1902), se desarrolló una crisis muy importante por la propuesta de algunos miembros de la Junta y de algunas «señoras curadoras» que plantearon sustituir a las enfermeras internas por las Hijas de la Caridad; propuesta a la que se opuso la hija del fundador, Sol Rubio y Chacón que también en 1916 publicó un libro titulado El Instituto Rubio y los Estatutos de su fundador. Defensa documentada, en el que denuncia entre otras cuestiones el incumplimiento de los Estatutos de 1896, además de considerar ilegal la reforma de dichos estatutos realizada en 1910.
Implementation of Pre-Cleaner as An Effort to Preventive Engine Lacks Power Bulldozer D85ess-2 Support Area Rom PT Putra Perkasa Abadi Site Mip Lahat
Authors: Jatmiko Fauzi , Hidayat Panca Nur , Triraharjo Joko , Kurniawan Fika , Saputra M. Ferry
Published: February 2025

Bulldozer D85ESS-2 operating in the ROM Support Area of PT Putra Perkasa Abadi Site MIP Lahat often experiences engine lacks power problem, which disrupts productivity and increases maintenance costs. This problem is generally caused by air contamination entering the engine system, resulting in decreased combustion efficiency and component damage. This study aims to analyse the effectiveness of pre-cleaner implementation as a preventive measure in overcoming this problem. The method used was a quantitative approach with the collection and analysis of operational data from the D85ESS-2 bulldozer before and after the installation of the pre-cleaner. The data analysed included the frequency of occurrence of the engine lacks power problem, downtime duration, and fuel usage. The results showed that the implementation of a pre-cleaner on the D85ESS-2 bulldozer at PT Putra Perkasa Abadi successfully resolved the problem of engine lacks power by reducing the accumulation of coal dust in the air cleaner. The test results show significant improvements in engine performance, with most parameters meeting the set standards. Thus, the use of a pre-cleaner improves combustion efficiency, reduces maintenance costs, and extends engine life.
The Role of Moving Teachers in Improving the Quality of Education through the Implementation of the Merdeka Curriculum
Authors: Wati Ariesta Dwi Indah Kusuma , Lestari Neta Dian
Published: February 2025

This study aims to explore the role of teacher leaders in improving the quality of education through the implementation of the Merdeka Curriculum in Indonesia. The Merdeka Curriculum offers flexibility to teachers and schools to create a contextual and relevant learning process to students’ needs, with a focus on character building and strengthening non-academic skills. The study used a literature study method to examine relevant theories and previous findings. The results of the study indicate that teacher leaders act as agents of change who are able to facilitate educational innovation, improve the quality of learning, and strengthen collaboration between stakeholders. The main challenges in implementing the Merdeka Curriculum include limited infrastructure, teacher readiness in using technology, and students’ socio-economic factors. However, with policy support and collaboration between schools, parents, and communities, teacher leaders can play a crucial role in ensuring that educational transformation is effective. This study provides recommendations for stakeholders to strengthen the Teacher Leader program and increase the success of the implementation of the Merdeka Curriculum.
Perceptions of Students on Differentiated Learning of Video Content in Long Multiplication Mathematics Lessons
Authors: Asnaini Desi
Published: February 2025

Currently, students often feel bored with the teaching and learning activities in the classroom, especially in Mathematics learning, for that a learning style approach is needed that is adjusted to the needs of each student. The purpose of studying content differentiation through videos for elementary school children is to provide a more meaningful learning experience and in accordance with the needs and learning styles of each student, facilitate diverse learning styles and provide an interactive learning experience. By using visual and auditory content videos, learning for grade 3 elementary school children greatly helps students understand the material to be studied; after watching the video, the teacher can interact directly with students through questions or quizzes based on the learning videos that have been watched by students. The method used in this study is qualitative, where this approach focuses on an in-depth understanding of socio-cultural phenomena and human behavior through non-numerical data. Qualitative research emphasizes the context of the process and quality rather than measurement. In this study, video content differentiation is a strategy where creators and content providers provide a variety of learning styles to students.
X-Ray Scanning Reduce Soluble Active Molecules of Mesenchymal Stem Cells
Authors: Putra Agung , Pasongka Zenitalia , Widyatmoko Agus , Prasetio Ardi , Dirja Bayu Tirta
Published: February 2025

Mesenchymal Stem Cells secrete various anti-inflammatory and regenerative SAMs-MSCs that possess immunomodulatory properties and may accelerate wound healing. As a potential agent for therapeutic, SAMs-MSCs should be stable in any condition, including under X-Ray Scanning. The previous study reveal that X-Ray Scanning may induce protein damage. However, the investigation regarding the stability of SAMs-MSCs under X-Ray Scanning is limited, thus this study aimed to investigate the stability of SAMs-MSCs after X-Ray Scanning. Mesenchymal Stem Cell medium was filtrated using the TFF method at 300 and 5 kDa filter cut off and sterilized using 0,1 um syringe. The SAMs-MSCs underwent X-ray Scanning using public Air Port X-Ray twice. The SAMs-MSCs concentration was measured using ELISA. T-test analysis was performed for the statistical analysis with P<0,05. This study revealed that X-ray scanning reduce the concentration of SAMs-MSC. A previous study found that x-ray irradiation may damage protein at 6–18 keV caused by the energy deposited by photoelectrons that are generated by the interaction of X-ray photons and the protein leading to photoelectron-induced damage.
The Effect of Low Dosage MSC-Conditioned Medium on Urea Levels in Acute Renal Failure
Authors: Istania Rizqi Windhu Sri , Kustyah Azizah Retno , Sa'dyah Nur Anna Chalimah
Published: February 2025

Background: Acute renal failure (ARF) is still associated with a high incidence of morbidity and mortality, as well as a high risk of developing chronic renal failure. ARF is a major public health problem, it is associated with high mortality, morbidity, and long-term risk of chronic kidney disease. One of the assessments of kidney function is the increase in serum urea in the body. The kidneys have an extraordinary ability to regenerate after injury and fully recover, and clinical options are limited to fluid management and dialysis procedures. The development of new strategies in order to increase the ability of kidney regeneration due to ARF, and to maintain kidney function both in the short term and in the long term is needed. This study aims to determine the effect of low-dose MSC-CM on urea levels in ARF. Method: This research is an in vivo research with the type of research Post Test Only Control Group Design. This study used a model of acute renal failure by inducing gentamicin and used 2 research groups, namely the control group (PBS), and the treatment group (MSC-CM 0.2. urea was examined using a spectrophotometer and then analyzed by unpaired t-test. Result: The results of this study showed that the mean urea levels between the control group (19.46 ± 0.56 mg / dL) and the treatment group (13.96 ± 0.73 mg / dL) were significantly different (p <0.05). Conclusion: The conclusion of this study indicated that there was an effect of low-dose of MSC-CM on urea levels in acute renal failure.
Trisindoline 5 Compound Inhibits Human Breast Cancer Stem Cell Formation by Downregulating the BCL-2 Gene Expression
Authors: Fatoni Muhammad , Salsabila Yofinta I , Nurhayati Awik P.D. , Ghaissani Shabrina Syifa , Santoso Mardi , Martak Fahimah
Published: February 2025

Background:  Breast cancer cell's growth and survival are supported by breast cancer stem cells (bCSCs) mammosphere formation. bCSCs represent a subpopulation of undifferentiated cancer cells which associated with self-renewing abilities, tumor initiation, drug resistance, and metastasis. Overexpression of the B Cell Lymphoma 2 (BCL-2) family in many tumor cells contributes to apoptosis resistance. Trisindoline is an indole trimer alkaloid natural compound that provides a cytotoxic effect on cancer cells. A new modification of trisindoline has been synthesized into trisindoline 5 in 2021. Objective: This study purposed to investigate the effect of trisindoline 5 compounds against BCL-2 gene expression in bCSCs in vitro. Methods: The bCSCs MDA-MB-231 were divided into control and treatment groups which were further analyzed in gene expression using the qPCR Livak method. Results: Based on gene expression analysis, the results showed that trisindoline 5 may decrease the expression of BCL-2 in MDA-MB-231 cells. Conclusion: This study concludes that trisindoline 5 could downregulate the antiapoptotic BCL-2 gene expression in bCSCs in vitro.
Polymeric Chitosan Gel Modulates Inflammatory Responses to Prevent Peritoneal Adhesion in Rats
Authors: Makarim Fadhli Rizal , Ekasaputra Vito Mahendra , Arnandha Defan Adlill , Sahardin Renaldy , Khayin Iqbal Yusuf
Published: February 2025

Peritoneal adhesions are a pathological response to injury that connects adjacent structures that cause by inflammatory response such as IL-1 and IL-6. The current strategies to minimize or prevent peritoneal adhesions are very limited. Chitosan was found have antiinflammatory effect. However, chitosan hydropphobic properties give poor solubility in physiological solvent such as peritoneal fluid. Our study aims to investigate the effect of polymeric chitosan gel in the prevention of peritoneal adhesion through modulating IL-1 and IL-6 after laparotomy.
Ten rats were divided into a control group and treated group. Laparotomy model was done with proper procedure. Illeum were scratch using cytobrush to mimic peritoneal adhesions. In the treated group, the defect was covered with Mediclore®. After 14 days, IL-1 and IL-6 were analyzed using ELISA from peritoneal fluid serum and macroscopic observation of adhesion were made.
All animals in control group showed high grade of adhesin while treated group showed a filmy peritoneal adhesion. Group treated with Mediclore® showed a lower IL-1 levels compared to control group. Treated group showed a better control at inflammation by scoring lower IL-6 levels compared to control group.
In conclusion, polymeric chitosan gel prevents peritoneal adhesions through modulation of inflammatory cytokines after laparotomy in rats.
Keywords: chitosan, IL-1, IL-6, peritoneal adhesions, laparotomy
Intracavernous Stem Cell Injection for Erectile Dysfunction: Safety and Efficacy Review
Authors: Lubis Ahmad Sulaiman , Makarim Fadhli Rizal , Aldiosta Pradipta Hadyan
Published: February 2025

Background: Erectile dysfunction is a common condition in men characterized by the inability to maintain an erectile state. Current treatment using phosphodiesterase-5 inhibitors treatment may leave significant side effects and effectivity problems in some patients. The use of stem cell transplantation in erectile dysfunction has been emerging as a replacement therapy for erectile dysfunction. The effectiveness of stem cell therapy for the treatment of erectile dysfunction has been investigated in several animal studies and one clinical trial in humans. The intracavernous injection is one of the methods to deliver stem cell treatment for erectile dysfunction besides intravenous and intraperitoneal. It was believed to improve erectile function by promoting cavernosal tissue regeneration, vascularization, and smooth muscle relaxation. However, the intracavernous injection of stem cells for erectile dysfunction treatment in clinical settings requires further investigation since its long-term efficacy and safety concerns regarding swelling, priapism, and fibrous plaque. Objective: This review aims to summarize the available evidence on the safety and efficacy of intracavernous stem cell injection for erectile dysfunction treatment in clinical studies only from PubMed. Conclusion: In conclusion, while the available evidence suggests that intracavernous stem cell injection is considered safe and effective for the treatment of erectile dysfunction, further large-scale clinical studies are needed to determine its long-term safety, efficacy, and optimal dosing regimens.
Clitoria ternatea Flower Extract Inhibits Matrix Mettaloproteinase-3 leading to the promotion of α-SMA Gene Expression in UVB-Induced Rat Model
Authors: Muna Nugraheni Itsnal , Amalina Nur Dina , Husain Sofian Azalia
Published: February 2025

This study aimed to determine the effect of administration of  Clitorea ternatea flower extract (C. ternatea) in a gel on the expression of MMP-3 and α-SMA in the skin of rat models induced by UVB light exposure. This research design is experimental research with a post-test control group design. This study was divided into four treatment groups: a healthy group, a UVB-negative control, a 5% C. ternatea gel treatment group (T1), and a 10% C. ternatea gel treatment group (T2). Negative control, T1, and T2 control groups were given UVB treatment with 302 nm energy of 160 mJ/cm2 for 5 days. In the treatment groups T1 and T2 were given the gel of C. ternatea from the 6th day until the 14th day. On day 15, all treatment groups were terminated, and the expression of MMP-3 and α-SMA genes was analyzed using qRT-PCR. In the 10% C. ternatea gel treatment group, there was a decrease in MMP-3 gene expression (0.73±0.26) and an increase in α-SMA gene expression (16.4±8.3) compared to the UVB control group which had gene expression. MMP-3 (3.24+1.05) and α-SMA gene expression (0.1±0.0). The administration of C. ternatea gel resulted in a reduction in the expression of the MMP-3 gene and an increase in the expression of the α-SMA gene. Overall, C. ternatea has the potential to prevent UVB-induced hyperpigmentation.
IMPLEMENTASI KREATIVITAS SISWA/I DALAM EDUKASI PENGETAHUAN DASAR PRO-AKTIF ANAK IMIGRAN INDONESIA DI MALAYSIA
Authors: Maulana Yoga Arif , Dewi Berliana Rosita , Sadubi Sultan Reynard , Amellia Nazwa , Sidik Aaliyah Maharani Putri , Andani Alifia Aulia , Madihah Maysa , Agusman Desi Destiana , Azizah Siti Nur
Published: February 2025

The decline in the interest of Indonesian students in learning can threaten the quality of education and human resources that have an important role in the future of the nation. Basic knowledge about civic and cultural education, which should be an important understanding for students, is not in line with expectations, especially for Indonesian students who are abroad. This is exacerbated by the negative effects of unsupervised use of gadgets, which makes students more interested in outside cultures and reluctant to learn about local cultures. In addition, the lack of competence of educators and unattractive learning methods also contribute to the low enthusiasm of students. To overcome this problem, we carry out a learning program by involving students' creativity in proactive basic knowledge education for Indonesian immigrant children at At-Tanzil Fostered School, Malaysia. This program involves 20 Kindergarten students and 7 students in grades 1-2 of Elementary School, and will be held on October 2, 2024 with the Youth.id Team. This program uses a learning approach that provides a space for creativity for students to actively participate in learning, which includes hygiene materials, mathematics, and cultural introduction. This approach is expected to increase students' interest in learning and contribute to the development of more effective and inclusive educational methods.
Obituarium Burilli (1934 - 2024)
Authors: Reinoso-Barbero Fernando
Published: February 2025

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Análisis del marco legal para las personas adultas mayores en el Ecuador: evolución y estado actual
Authors: Montoya Rusty Murillo
Published: February 2025

Resumen: El motivo del presente artículo es precisar la evolución en el Ecuador respecto a políticas en beneficio de los adultos mayores hasta la conformación actual de la Ley Orgánica de Las Personas Adultas Mayores (LOPAM). Para lograr este objetivo, se aplicó una investigación de tipo exploratoria con diseño documental. Se revisó, deconstruyó y sistematizó diferentes fuentes bibliográficas publicadas en revistas científicas, registros oficiales de normativas y leyes expedidas en Ecuador como la Ley Especial del Anciano de 1991, para así comprender los procesos y los cambios o ajustes registrados en la Ley Orgánica de las Personas Adultas Mayores (LOPAM) y su reglamento general publicado en el año 2020. Así también, haciendo uso del método histórico se pudo elaborar una esquematización cronológica de sucesos determinantes que se llevaron a cabo para la creación de la actual LOPAM. El análisis crítico sobre la relación de la LOPAM y, el reglamento de esta con tratados y acuerdos internacionales emitidos en favor de los adultos mayores de 65 años permitió evidenciar el planteamiento de la hipótesis: H1: Las bases legales referentes a políticas de vejez en el Ecuador están sustentadas en las bases legales y documentos internacionales que existen actualmente referente a los derechos de los adultos mayores de 65 años. El estudio efectuado determina que la LOPAM mantiene objetivos con fines asistencialistas, dejando de lado la repotenciación de habilidades y destrezas en los adultos mayores a través de las cuales se les pueda dar ese verdadera libertad e inclusión: social, productiva e intergeneracional.
Interacción con Inteligencias Artificiales: Impacto Psicosocial en Estudiantes Universitarios Españoles
Authors: Ceinos Fernández Ignacio , Fernández Corbella Sandra , Martínez Santiago Teresa
Published: February 2025

En el vertiginoso avance de la Inteligencia Artificial (IA) en nuestra sociedad, entender la reacción social y las emociones asociadas es crucial. Esta investigación explora cómo los y las jóvenes universitarias en España perciben y responden a la IA en su vida cotidiana. ¿Qué emociones despiertan en ellos estas tecnologías? A través de nueve grupos focales, se examinaron sus sensaciones, el grado de uso de la IA, sus reacciones emocionales y consideraciones éticas. Los hallazgos revelan dos posturas dominantes: una de indiferencia, que acepta y justifica los beneficios de la IA, y otra de rechazo, marcada por el miedo y la desconfianza. Además, se identifica una contradicción en los discursos: los jóvenes critican los posibles efectos negativos de la IA, pero la utilizan habitualmente, generando una notable disonancia cognitiva. Este estudio proporciona una visión integral de las emociones y percepciones de los nativos digitales frente a la IA, subrayando la necesidad de abordar las preocupaciones éticas y emocionales en su desarrollo y adopción.
Advancements in microfluidic technologies for point-of-care diagnostics and treatment
Authors:   Kampala International University, Kampala, Uganda, A Uzorka , B Musa ,   Kampala International University, Kampala, Uganda, D Kibirige ,   Kampala International University, Kampala, Uganda, D Makumbi ,   Kampala International University, Kampala, Uganda
Published: February 2025

Healthcare game-changers include point-of-care (POC) medical microdevices that are driven by microfluidic technologies. These micro, transportable technologies revolutionize patient care by offering quick diagnosis, individualized treatments, and monitoring. This study examines the most recent developments in microfluidic POC technologies with an emphasis on systems for organ-on-a-chip, drug administration, and blood analysis. Recent developments have improved disease modeling, permitted precise drug administration, and made blood analysis more patient-centric. Patient care and remote monitoring are improved by integration and communication with healthcare systems. Regulating organizations and cost effectiveness remain problems, though. The advent of sustainable technologies, artificial intelligence (AI) integration, and tailored medication will pave the road for affordable, effective healthcare.