bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Pembelajaran Sains MI Bermuatan Karakter Islam Dengan Setting Model Pembelajaran Sains Teknologi Masyarakat
Authors: Nugroho Irham , Iman Muis Sad
Published: February 2019

Artikel ini menyajikan penelitian R&D yang bertujuan untuk: (1) Menghasilkan validitas dan kelayakan perangkat pembelajaran sains MI bermuatan karakter islami dengan setting model pembelajaran sains teknologi masyarakat (STM), (2) Menganalisis efektivitas perangkat pembelajaran yang dikembangkan dalam meningkatkan karakter islami dan keterampilan berpikir kreatif dengan setting sains teknologi masyarakat (STM) dan model pembelajaran konvensional. Pengembangan perangkat pembelajaran ini mengacu pada model pengembangan 4-D yaitu Define (Pendefinisian), Design (Perancangan), Develop (Pengembangan) dan Disseminate (Penyebaran). Data dianalisis secara deskriptif kualitatif dan persentase keterlaksanaan perangkat pembelajaran yang dikembangkan. Hasil yang telah dicapai pada penelitian ini adalah: (1) Telah berhasil dikembangkan perangkat pembelajaran sains MI dengan setting model pembelajaran sains teknologi masyarakat (STM) di MI yang di dalamnya mencakup pemahaman peserta didik terhadap karakter islami serta mengukur keterampilan berpikir kreatif siswa; (2) Instrumen efektivitas perangkat pembelajaran yang dikembangkan ini masih melalui serangkaian tahapan validasi meski telah disimulasikan oleh peneliti pada pelaksanaan pembelajaran sains MI.
PENERAPAN MODEL KOOPERATIF TIPE THINK-PAIR-SHARE UNTUK MENINGKATKAN KECERDASAN LINGUISTIK SISWA SEKOLAH DASAR
Authors: Nining Nining
Published: February 2019

Penelitian ini dilatarbelakangi oleh rendahkan kecerdasan linguistik siswa kelas VI SDN Cipaku 03 Kecamatan Paseh Kabupaten Bandung Tahun Ajaran 2017-2018. Tujuan penelitian yang dilakukan yaitu untuk mengetahui peningkatan kecerdasan linguistik siswa kelas VI SD dengan menggunakan model kooperatif tipe think-pair-share. Metode penelitian yang digunakan yaitu metode Penelitian Tindakan Kelas (PTK), dimana PTK ini merupakan suatu upaya yang dilakukan pendidik dalam rangka memperbaiki praktek pembelajaran di kelas, sehingga PTK ini sangatlah baik dilaksanakan oleh para guru untuk meningkatkan mutu pembelajaran dan meminimalisir masalah yang muncul pada saat praktek pembelajaran. Adapun instrumen yang diguanakan yaitu lembar observasi, lembar tes kecerdasan linguistik, lembar wawancara, dan jurnal catatan guru. Berdasarkan data yang diperoleh dari tes kecerdasan lingusitik siswa, telah diperoleh penemuan bahwa terjadinya peningkatan-peningkatan mengenai hasil tes kecerdasan lingusitik siswa, sehingga dapat diperoleh hasil penelitian bahwa model kooperatif tipe think-pair-share dapat meningkatkan kecerdasan lingusitik siswa. Oleh karena itu penulis merekomendasikan model kooperatif tipe think-pair-share kepada para guru sebagai salah satu alternatif dalam upaya meningkatkan kecerdasan lingusitik siswa dalam pembelajaran Bahasa Indonesia di SD.
Bölgesel Güvenlik Kompleksi Teorisi Bağlamında Türkiye-İran Arasında Göç ve Sınır Güvenliği
Authors: Birdişli Fikret , Gören Merve
Published: February 2019

Soğuk Savaş sonrası uluslararası
alanın geleceği ile ilgili öne sürülen tezlerden biri de Kopenhag Ekolü
bağlamında geliştirilen Bölgesel Güvenlik Kompleksi Teorisidir (RSCT). Bu
teoriye göre dünya ortak sorunlara sahip, iç dinamikleri açısından göreceli
olarak homojen alanların oluşturduğu güvenlik bölgelerine ayrılabilir.
Uluslararası alanın yeni çatışma alanları ve dinamikleri de bölge içi ya da
bölgeler arası gerilimlerden kaynaklanacaktır. Bu kapsamda tanımlanan
bölgelerden biri de Ortadoğu Güvenlik Kompleksidir. İran ve Türkiye aynı
coğrafyada yer alan ortak sınırlara sahip iki komşu devlet olmalarına karşın bu
teoride öznel nitelikleri dikkate alınarak farklı tanımlanmıştır. Buna göre
İran Ortadoğu Güvenlik Kompleksinin lokal bir ülkesi iken Türkiye Ortadoğu ve
Batı arasında yalıtkan bir ülke olarak bulunmaktadır. Teoride bölge içi
güvenlik dinamikleri analiz edilirken bölgelerarası yalıtkan ülkeler ile lokal
ülkeler arasındaki ilişki tam olarak açıklanmamıştır. Buradan yola çıkarak bu
makalede Türkiye ve İran arasındaki güvenlik sorunları göç ve sınır güvenliği
üzerinden incelenmiş, bu yolla lokal ve yalıtkan ülkeler arasındaki ilişkinin
açıklanması amaçlanmıştır. Araştırmanın sonunda elde edilen bulgulara göre
Türkiye ve İran arasındaki göç ve sınır güvenliği sorunları iki ülke arasındaki
çatışan ilişkilere dayalı olmaktan çok Bölge içindeki konumlarına uygun bir
niteliğe sahiptir.
A (IN)EFICÁCIA DAS MEDIDAS SOCIOEDUCATIVAS
Authors: Machiavelli Jociane Oufella , Da Silva Gislaine , Dos Santos Adelcio Machado
Published: February 2019

O presente trabalho trata da (In)Eficácia das Medidas Socioeducativas e apresenta as peculiaridades estabelecidas pelo Estatuto da Criança e do Adolescente, propondo-se a apurar como tais medidas se revelam no processo de reeducação dos adolescentes infratores. Na primeira parte, abordar-se-á a evolução dos Direitos da Criança e do Adolescente e também os princípios que oferecem proteção a eles. Em um segundo momento, o estudo apontará cada uma das Medidas Socioeducativas e seus desdobramentos previstos no Estatuto da Criança e do Adolescente. Por fim, analisar-se-á a eficácia das Medidas Socioeducativas aplicadas na Comarca de Caçador/SC. Destaca-se que o estudo faz uso do método indutivo associado à pesquisa bibliográfica e ao levantamento de dados, observando a Normalização dos Trabalhos Acadêmicos da Universidade Alto Vale do Rio do Peixe (UNIARP) e as regras da Associação Brasileira de Normas Técnicas (ABNT). Isso posto, conclui-se que as medidas socioeducativas são eficazes, na comarca de Caçador/SC, tendo em vista que a maior parte dos adolescentes infratores não só cumpriu a medida socioeducativa imposta, mas também não voltou a reincidir na prática de ato infracional.

Palavras-chave: Ato infracional. Medidas Socioeducativas. Estatuto da Criança e do Adolescente.
THE INEQUACY OF SOCIO-EDUCATIONAL MEASURES

Abstract: This paper deals with the (In) Effectiveness of Socio-Educational Measures and presents the peculiarities established by the Statute of the Child and Adolescent, proposing to determine how such measures are revealed in the process of re-education of juvenile offenders. In the first part, the evolution of the Rights of the Child and the Adolescent, as well as the principles that offer protection to them, will be addressed. In a second moment, the study will point out each of the Socio-educational Measures and its planned developments in the Statute of the Child and the Adolescent. Finally, it will be analyzed the effectiveness of the Socio-educational Measures applied in the Region of Caçador/SC. It is worth noting that the study uses the inductive method associated with bibliographic research and data collection, observing the Standardization of Academic Papers of the University of Vale do Rio do Peixe (UNIARP) and the Brazilian Association of Technical Standards (ABNT). That said, it is concluded that socio-educational measures are effective in the region of Caçador/SC, considering that most of the juvenile offenders not only fulfilled the imposed socio-educational measure, but also did not return to repeat the practice of an infraction.

Keywords: Infraction. Socio-educational Measure. Child and Adolescent Statute.
A JUSTIÇA RESTAURATIVA COMO MEIO PARA MANUTENÇÃO DA MENORIDADE PENAL
Authors: Philippi Patrícia Pasqualini , Wehmuuth Caroline Testoni
Published: February 2019

Resumo: O objetivo do presente estudo, desenvolvido através de pesquisa bibliográfica realizada a partir do método indutivo, foi apresentar a origem do Tribunal do Júri no Brasil, bem como expor breves considerações sobre as principais características desse instituto na Inglaterra, Estados Unidos, Itália, França, Portugal, Espanha e no Brasil. Com origem incerta, o instituto do Tribunal do Júri tem sido o modo de resolução de conflitos desde a sua criação, evoluindo  de formas diversificadas nos países do mundo. No Brasil, seu surgimento se deu ainda na época do Brasil Império, quando o país era uma colônia de Portugal.

Palavras-chave: Tribunal do Júri; Direito Comparado; História do Direito; Common Law; Civil Law.
THE IMPLEMENTATION OF THE JURY COURT IN BRAZIL AND ITS CHARACTERISTICS IN THE MAIN COUNTRIES OF THE WORLD

Abstract: With uncertain origin, the institute of the Court of the Jury has been the mode of conflict resolution since its inception. In Brazil, its emergence occurred even in the time of Brazil Empire, when the country was a colony of Portugal. The objective of this study, developed through a bibliographical research based on the inductive method, was aimed at presenting the origin of the Jury's Court in Brazil, as well as presenting concise notes on the main characteristics of this institute in the United States United States, Italy, France, Portugal, Spain and Brazil.

Keywords: Jury Court; Comparative Law; The History of Law; Common Law; Civil Law.
PERFIL EPIDEMIOLÓGICO DE USUÁRIOS DE PSICOTRÓPICOS DE UM CAPS DA ZONA DA MATA DO ESTADO DE RONDÔNIA
Authors: Franskoviak Leidiane Dias , Silva Tânia Eugênia da , Carlotto Marielli Da Silva , Batista Eraldo Carlos
Published: February 2019

O objetivo deste trabalho foi delinear o perfil epidemiológico dos usuários do CAPS do município de Rolim de Moura, no Estado de Rondônia, que foram medicalizados com psicotrópicos no ano de 2014. Trata-se de uma pesquisa documental, de abordagem quantitativa e de natureza descritiva. Os resultados mostraram predominância do gênero feminino, 70,7%, bem como a faixa etária de 40 a 60 anos, com 56,1% para ambos os sexos. Com relação ao estado civil, a maioria, 47,3%, é casada e estudou apenas até o ensino fundamental. Entre as ocupações, lideram as donas de casa para as mulheres, 37,55%, e a de agricultor, 14,33%, entre os homens. As hipóteses de diagnóstico mostram prevalência de Depressão, 40,8%, entre as mulheres e, 29,5%, entre os homens. Quanto aos psicofármacos, os antidepressivos seguidos dos ansiolíticos lideram como medicamentos mais dispensados no período investigado. Concluiu-se que as características da população estudada apontam para a necessidade de desenvolvimento de estratégias de apoio psicossocial que proporcionem ações efetivas na prevenção e no cuidado da saúde mental dos usuários.Palavras-chave: Psicotrópicos. CAPS. Perfil epidemiológico. ABSTRACT: The objective of this research was to outline the epidemiological profile of CAPS users in the municipality of Rolim de Moura in the Rondonia State, who were medicalized with psychotropic drugs in 2014. This is a documental research, with a quantitative approach of descriptive nature. The results shown predominance of women, 70.7%, with an age group ranging from 40 to 60 years, with 56.1% for both genders. Regarding marital status, the majority, 47.3%, is married and studied only up to primary school. Among the occupations, the housewives led for women, 37.55%, and farmer, 14.33% to men. Diagnosis hypotheses show prevalence of Depression, 40.8%, between women and, 29.5%, between men. As for the psychotropic, the antidepressants followed by anxiolytics led as most dispensed drugs during the investigated period. It was concluded that the characteristics of the studied population point towards the need of developing strategies for psychosocial support, which provide effective actions in the prevention and care of the mental health of users.Keywords: Psychotropic. CAPS. Epidemiological profile.
RESÍDUOS SÓLIDOS URBANOS DISPOSTOS EM TERRENOS BALDIOS DA CIDADE DE CHAPECÓ, SC
Authors: Neves Luana Melim , Lutinski Junir Antônio , Tiburski Jessica
Published: February 2019

Entre os problemas ambientais provenientes do desenvolvimento atual destaca-se o aumento da geração de resíduos sólidos urbanos (RSU). Estes resíduos estão associados à poluição e impactam a saúde humana. Este estudo teve como objetivo caracterizar os RSU depositados em terrenos baldios (TB) da cidade de Chapecó (SC) quanto à frequência, a origem e a classificação. Foram avaliados 100 TB em 10 bairros da cidade, no período entre maio e junho de 2016. Foi verificada a presença de RSU em 72% dos terrenos avaliados. A origem foi identificada como residencial em 65% dos casos, da construção civil em 30%, de origem comercial em 23% e industrial em 1%. Quanto à classificação, resíduos a classe IIA (resíduos não perigosos não inertes) foram identificados em 52% dos TB, resíduos pertencentes à classe IIB (resíduos inertes) foram registrados em 49% e resíduos perigosos em 9%. Os resultados indicam a necessidade de o município ampliar o gerenciamento de RSU e de uma política pública integrada envolvendo todos os segmentos da sociedade para a gestão dos mesmos. Os resultados desse estudo poderão subsidiar ações para o desenvolvimento social e econômico do município bem como para a conservação dos recursos naturais e das condições de saúde da comunidade. Recomenda-se um programa de educação ambiental e fiscalização voltada para mobilização da comunidade em prol a separação e destinação correta dos RSU.Palavras-chave: Contaminação do solo. Degradação ambiental. Educação ambiental. Gestão ambiental. Urbanização. ABSTRACT: Among the environmental problems arising from population growth are the increase in the generation of urban solid waste (RSU). These wastes are associated with pollution and impact human health. The aim of this study was to characterize the RSU deposited in vacant lots (TB) in the Chapecó city (SC) regarding frequency, origin and classification. A total of 100 TB were evaluated in 10 city districts between May and June 2016. The presence of RSU was verified in 72% of the evaluated lots. The identified origin was residential in 65% of cases, civil construction in 30%, commercial origin in 23% and industrial in 1%. Class IIA (non-inert non-hazardous waste) was identified in 52% of TB, class IIB (inert waste) was recorded in 49% and hazardous waste in 9%. This study indicates the need for the municipality to improve RSU management and an integrated public policy involving all segments of society for manage them. The results of this study may subsidize actions for the social and economic development of the municipality as well as for the conservation of natural resources and community health conditions. It is recommended an environmental education and inspection program aimed at mobilizing the community in favor of the separation and correct RSU destination.Keywords: Soil contamination. Environmental degradation. Environmental education. Environmental management. Urbanization.
SÍFILIS CONGÊNITA: UMA ANÁLISE DO PERFIL EPIDEMIOLÓGICO NO MUNICÍPIO DE CRICIÚMA
Authors: Rosso Luana , Martins Mariá Vaz Franco , Soratto Maria Tereza , Thomé Ivanir Prá da Silva , Souza Rozilda Lopes de
Published: February 2019

A sífilis é uma doença infecciosa sistêmica de evolução crônica e muitas vezes assintomática, transmitida principalmente por via sexual e vertical. O estudo em questão trata-se de um estudo de corte transversal, retrospectivo, descritivo de natureza quantitativa e documental, a coleta de dados se deu no Programa de Atenção Municipal as DST/HIV/AIDS (PAMDHA) do município de Criciúma, através de pesquisa documental com base nos dados da Vigilância Epidemiológico do SINAN com o objetivo de investigar os casos de sífilis congênita no município. Através da pesquisa pode-se perceber que entre os anos de 2015 e 2016 constatou 3,7% do total de casos pesquisados chegaram a óbito, dos RN nascidos com sífilis 51,9% foram assintomáticos e 3,8% sintomáticos, os demais não apresentaram características. Do total de gestantes, 66,6% realizou pré-natal e foram diagnosticadas a partir do mesmo, possibilitando o tratamento. Para que haja uma menor prevalência de casos de sífilis é necessário que os profissionais da saúde adotem, além das políticas públicas já disponíveis outros hábitos que levem ao alcance de todas as classes de gestantes, para evitar mais casos de sífilis.Palavras-chave: Gestantes. Sífilis Congênita. Recém-Nascidos. Infecções Sexualmente Transmissíveis. CONGENITAL SYPHILIS: AN ANALYSIS OF THE EPIDEMIOLOGICAL PROFILE IN THE CITY OF CRICIÚMA ABSTRACT: Syphilis is a systemic infectious disease of chronic evolution and often asymptomatic, transmitted mainly through sexual and vertical. The study in question it is a cross-sectional study, retrospective, descriptive quantitative and documentary nature, data collection took place in the Attention the Municipal STD/HIV/AIDS (PAMDHA) of the city of Criciúma, through documentary research based on Epidemiological Surveillance data from SINAN aiming to investigate the cases of congenital syphilis in the municipality. Through research you can notice that between the years 2015 and 2016 found 3.7% of total cases surveyed came to death, the RN born with syphilis 51.9% 3.8% were asymptomatic and symptomatic, the others did not show characteristics. Of the total of 66.6% pregnant women, prenatal and conducted were diagnosed from the same, allowing the treatment. So there is a lower prevalence of syphilis cases is necessary that health professionals adopt, in addition to the already available public policies other habits that lead to reach of all classes of pregnant women, to prevent more cases of syphilis.Keywords: Pregnant women. Congenital Syphilis. Newborns. Sexually Transmitted Infections.
PERCEPÇÃO DO ENFERMEIRO ACERCA DAS ATIVIDADES EM EDUCAÇÃO EM SAÚDE NA ESTRATÉGIA SAÚDE DA FAMÍLIA
Authors: Santos Daniela , Oliveira Pamela Scarlatt Duraes , Rodrigues Adriana Barbosa , Miranda Sérgio Vinícius Cardoso de
Published: February 2019

Objetivo: Buscou-se com o presente trabalho conhecer a percepção do enfermeiro acerca das atividades em Educação em Saúde na Estratégia Saúde da Família. Método: Estudo com abordagem qualitativa, com enfermeiros atuantes em Estratégias Saúde da Família localizadas no município de Montes Claros, Minas Gerais, realizado no mês de setembro de 2016, com aplicação de um questionário semi-estruturado com seis perguntas norteadoras. Resultados: A análise de dados possibilitou a construção de três categorias centrais, a saber: Objetivos e prática da educação em saúde, Estratégia Saúde da Família: porta de entrada e Aspectos facilitadores e dificultadores da educação em saúde. Conclusão: Compreende-se que a Educação em Saúde representa ferramenta ímpar e sempre inovadora no campo da saúde para transformar a vida das pessoas e o processo saúde-doença do indivíduo e comunidade.Palavras-chave: Educação em saúde. Estratégia Saúde da Família. Enfermeiro. NURSES' PERCEPTION ABOUT ACTIVITIES IN HEALTH EDUCATION IN FAMILY HEALTH STRATEGY ABSTRACT: Objective: The aim of this work was to know the nurse's perception about the activities in Health Education in the Family Health Strategy. Method: A qualitative study with nurses working in Family Health Strategies located in the city of Montes Claros, Minas Gerais, Brazil, in September 2016, with the application of a semi-structured questionnaire with six guiding questions. Results: The data analysis allowed the construction of three central categories, namely: Objectives and practice of health education, Family Health Strategy: gateway and aspects of facilitating and hindering health education. Conclusion: It is understood that Health Education represents a unique and always innovative tool in the field of health to transform people's lives and the health-disease process of the individual and community.Keywords: Health Education. Family Health Strategy. Nurse.
Meningkatkan Disposisi Matematis Siswa dengan Menggunakan Pembelajaran Berbasis Penemuan Terbimbing
Authors: Rahman Taufik
Published: February 2019

Kemampuan yang dianalisis dalam penelitian ini adalah Kemampuan disposisi matematis.  Disposisi matematis dirasa cukup penting karena kemampuan ini tertuang dalam tujuan pembelajaran matematika SMA yang berbunyi memiliki sikap menghargai kegunaan matematika dalam kehidupan, yaitu memiliki rasa ingin tahu, perhatian, dan minat dalam mempelajari matematika, serta sikap ulet dan percaya diri dalam pemecahan masalah. Penelitian ini bertujuan untuk mengetahui peningkatan disposisi matematis siswa di salah satu SMK di Kota Bandung antara yang memperoleh pembelajaran penemuan terbimbing dengan yang memperoleh pembelajaran konvensional. Sampel dalam penelitian ini adalah salah satu  SMK di Kota Bandung yang dipilih sebanyak 2 kelas yaitu kelas pertama memperoleh pembelajaran penemuan terbimbing dan kelas kedua memperoleh pembelajaran konvensional. Metode dalam penelitian ini adalah kuasi ekperimen. Instrumen dalam penelitian ini adalah soal non tes berupa angket yang terdiri dari 15 pernyataan positif dan  10 pernyataan negatif. Hasil dari Penelitian ini adalah peningkatan disposisi matematis siswa yang memperoleh pembelajaram penemuan terbimbing lebih baik dibandingkan dengan siswa yang memperoleh pembelajaran konvensional.Kata Kunci : Disposisi Matematis, Penemuan Terbimbing, Pembelajaran Konvensional
Las PyMEs en Santa Cruz, Análisis, Distribución e Innovación Vinculada al uso de las TICs
Authors: Aroca Bavich Alejandro , Martínez Llaneza Daniel , Ossandon Iván , García Rafael
Published: February 2019

El proyecto de investigación asociado a esta publicación pretende el estudio y acercamiento a las Pymes radicadas en la región con el fin de determinar los rasgos sobresalientes que estas tienen en materia de gerenciamiento. Se buscó indagar sobre las Pymes para determinar concretamente si realizan Planeamiento Estratégico, si las políticas de Recurso Humanos se vinculan a dicho Planeamiento y si desde estas empresas se incorpora innovación tecnológica y de qué modo incorpora el avance tecnológico en su función de producción. A tales fines se llevó adelante una campaña de relevamiento mediante encuestas que permitió estudiar e inferir el comportamiento de las organizaciones empresariales al respecto de varios de estos aspectos, la presente publicación logra caracterizar las pymes en conceptos generales y da evidencia del avance e incorporación de las Tecnologíasde Información y Comunicación en las PyMEs, explicando los principales mecanismos de innovación en esta materia.
PENGARUH PERSEPSI MANFAAT, PERSEPSI KEMUDAHAN, PERSEPSI KENYAMANAN, NORMA SUBJEKTIF DAN KEPERCAYAAN TERHADAP MINAT MENGGUNAKAN ELECTRONIC COMMERCE
Authors: MONICA NINA , TAMA ANNAFI INDRA
Published: February 2019

This study aims to determine the effect of perceive of usefullnes, perceived ease of use, convenience perception, subjective norms and beliefs to the interest of using electronic commerce in UNISMA students. This research using PLS (Partial Least Square) data analysis technique, with 88 respondents. The results indicate that perceived of usefullness, convenience perception, and beliefs have positif and significant effect to the interest of using e-commerce. Otherwise, perceived ease of use, and subjective norms have no effect.
Implementasi E-Problem Based Learning (E-PBL) Akuntansi Manajemen Pada Mahasiswa Stie Asia Malang
Authors: Murniati Aniek , Hermawan Aditya
Published: February 2019

This study is a descriptive study on the implementation of E-problem based learning (EPBL) Management accounting. The research data is based on observation ofthe application of learning method. Observation is done by interviewing and observingstudents who are implementing e-PBL in management accounting courses. Observations and interviews on lecturers who implement this learning model. Theresults explained that E-PBL facilitate students and lecturers to deliver learningmaterials and evaluate or utilize facilities provided by departments / agencies. E-PBL is alearning will help lecturers to facilitate the delivery of learning materials for easy tounderstand students. E-PBL in Evaluation / assessment of learning as one way to determine the ability ofstudents in following the learning will be very easy. With e-PBL, every studentautomatically has to be absent online. to the task also can directly check online.Communication and inertaksi among lecturers, students will be easier.
Kajian Pendapatan Non Halal Dan Dampak Penggunaannya Terhadap Reputasi Dan Kepercayaan Nasabah Perbankan Syariah
Authors: Muchlis Saiful , Utomo Husain Soleh
Published: February 2019

This study aims to determine the form of non-halal income and the impact on reputation and customer trust that is found in sharia banking, especially in PT Bank Muamalat Indonesia Makassar branch. This study used qualitative method based on interpretive paradigm with case study approach, to explain the phenomena that occur in the social scope or the scope of the company. Interview and financial statement analysis is used to gather data. The results of this study indicate that the non-halal income in PT Bank Muamalat Indonesia, Makassar Branch is from interest revenue of deposit in the other banks, and it’s derived to the declining of customer trust, then it can affect to the Bank’s reputation.
Pengaruh Struktur Corporate Governance Dan Risiko Perusahaan Terhadap Fee Audit
Authors: Suryanto Rudy , Siskawati Sinta Aria Dewi , Sofyani Hafiez
Published: February 2019

This study aims to analyze and provide empirical evidence of the influence of corporate governance structure and client risk towards audit fees. Corporate governance structure in this study uses the existence of independent commissioner, audit committee and majority shareholder. The bond ratings is used to measure client risk. This study uses secondary data from Indonesian Capital Market Directory (ICMD), annual reports, and bond ratings from PT. PEFINDO of companies which listed on Bursa Efek Indonesia in 2012-2013. This study uses purposive sampling method and resulted 104 firms. The method of analysis of this study used multi regression with SPSS 15.0. Program. The results indicate that corporate governance structure had no influence on audit fees, client risk have a positive influence on audit fees.
Influenced Factors Of E-Money Adoption
Authors: Nurhidayat Farid
Published: February 2019

This research aims to identify the factors that influence the adoption of e-money in Yogyakarta, Jakarta and Surabaya. It also aims to test formed model of e-money adoption through some variables; perceived of usefulness, perceived ease of use. There are 300 people from Jakarta, Surabaya and Yogyakarta as research samples. Data analysis used here is Structural Equation Model (SEM). Research result shows that the factors which influenced e-money adoption are subjective norm, perceived usefulness and perceived ease of use. This model is able to clarify the connection among influenced factors of e-money adoption. The implication of the research result to the publisher who provide e-money is to perceived usefulness and perceived ease of use factors, so it will gain more trust from every people to adopt e-money
Dunn’s Model of Sensory Processing: An Investigation of the Axes of the Four-Quadrant Model in Healthy Adults
Authors: Metz Alexia E. , Boling Daniella , DeVore Ashley , Holladay Holly , Liao Jo Fu , Vlutch Karen Vander
Published: February 2019

We examined the behavioral response (BR) and threshold (T) axes of Dunn’s four-quadrant model of sensory processing (1997). We assessed whether they are ordinal ranges and if variation is associated with other similarly described characteristics: Introversion/Extraversion (I/E) of Eysenck’s personality model (Sato, 2005), and somatosensory event related potentials (SERP) and their gating (Davies & Gavin, 2007). From healthy adults (n = 139), we obtained: Adult/Adolescent Profile (A/ASP, Brown & Dunn, 2002) and Eysenck’s Personality Questionnaire, Brief Version (Sato, 2005) scores and peak amplitude and gating factor of SERP P50. We found that BR scores did not differ across normative categories of the A/ASP, but T scores significantly increased along the axis. I/E scores did not vary with BR scores. There were no differences or correlations in P50 amplitudes and gating with T scores. The findings suggest that the BR axis may not reflect a construct with ordinal range, but the T axis may. Dunn’s concept of BR appears to be distinct from Eysenck’s concept of I/E. SERP and its gating may not be directly reflective of sensory processing thresholds in healthy adults. Conclusions are limited by having few participants with passive behavior regulation or low threshold patterns of processing.
The Desire to Better Understand Older Adults with Solid Tumors to Improve Management: Assessment and Guided Interventions—The French PACA EST Cohort Experience
Authors: Boulahssass Rabia , Gonfrier Sebastien , Champigny Noémie , Lassalle Sandra , François Eric , Hofman Paul , Guerin Olivier
Published: February 2019

Todays challenge in geriatric oncology is to screen patients who need geriatric follow-up. The main goal of this study was to analyze factors that identify patients, in a large cohort of patients with solid tumors, who need more geriatric interventions and therefore specific follow-up. Between April 2012 and May 2018, 3530 consecutive patients were enrolled in the PACA EST cohort (France). A total of 3140 patients were finally enrolled in the study. A Comprehensive Geriatric Assessment (CGA) was performed at baseline. We analyzed the associations between factors at baseline (geriatric and oncologic factors) and the need to perform more than three geriatric interventions. The mean age of the population was 82 years old with 59% of patients aged older than 80 years old. A total of 8819 geriatric interventions were implemented for the 3140 patients. The percentage of patients with three or more geriatric interventions represented 31.8% (n = 999) of the population. In multivariate analyses, a Mini Nutritional assessment (MNA) <17, an MNA ≤23·5 and ≥17, a performans status (PS) >2, a dependence on Instrumental Activities of Daily Living (IADL), a Geriatric Depression Scale (GDS) ≥5, a Mini Mental State Examination (MMSE) <24, and a Screening tool G8 ≤14 were independent risk factors associated with more geriatric interventions. Factors associated with more geriatric interventions could assist practitioners in selecting patients for specific geriatric follow-up.
Hereditary Pancreatic Cancer: A Retrospective Single-Center Study of 5143 Italian Families with History of BRCA-Related Malignancies
Authors: Toss Angela , Venturelli Marta , Molinaro Eleonora , Pipitone Stefania , Barbieri Elena , Marchi Isabella , Tenedini Elena , Artuso Lucia , Castellano Sara , Marino Marco , Tagliafico Enrico , Razzaboni Elisabetta , De Matteis Elisabetta , Cascinu Stefano , Cortesi Laura
Published: February 2019

The identification of BRCA mutations plays a crucial role in the management of hereditary cancer prevention and treatment. Nonetheless, BRCA-testing in pancreatic cancer (PC) patients is not universally introduced in clinical practice. A retrospective analysis was conducted, firstly, to evaluate the rate of BRCA-positive families among those presenting a family history of PC besides breast and/or ovarian cancer. Secondly, the relationship between BRCA pathogenic variants and PC risk was evaluated. Finally, the characteristics of PC developed in BRCA families were described. Among 5143 family trees reporting breast and/or ovarian cancer cases, 392 showed a family history of PC. A total of 35 families (24.5% selected by the Modena Criteria and 21.3% by the NCCN Criteria) were positive to BRCA testing. Among the BRCA1 mutations, 36.8% were found within a region defined by c.3239–c.3917, whilst 43.7% of BRCA2 mutations were located within c.7180–c.8248. This study confirmed that an increase in the rate of positive tests in families with PC when associated to breast and/or ovarian tumors. Moreover, this analysis indicated two possible Pancreatic Cancer Cluster Regions that should be verified in future research. Finally, PC in families with breast and/or ovarian cancer history, particularly in BRCA families, were diagnosed at younger age and showed better one-year overall survival.
CircSMARCA5 Regulates VEGFA mRNA Splicing and Angiogenesis in Glioblastoma Multiforme Through the Binding of SRSF1
Authors: Barbagallo Davide , Caponnetto Angela , Brex Duilia , Mirabella Federica , Barbagallo Cristina , Lauretta Giovanni , Morrone Antonio , Certo Francesco , Broggi Giuseppe , Caltabiano Rosario , Barbagallo Giuseppe , Spina-Purrello Vittoria , Ragusa Marco , Di Pietro Cinzia , Hansen Thomas , Purrello Michele
Published: February 2019

Circular RNAs are a large group of RNAs whose cellular functions are still being investigated. We recently proposed that circSMARCA5 acts as sponge for the splicing factor Serine and Arginine Rich Splicing Factor 1 (SRSF1) in glioblastoma multiforme (GBM). After demonstrating by RNA immunoprecipitation a physical interaction between SRFS1 and circSMARCA5, we assayed by real-time PCR in a cohort of 31 GBM biopsies and 20 unaffected brain parenchyma controls (UC) the expression of total, pro-angiogenic (Iso8a) and anti-angiogenic (Iso8b) mRNA isoforms of Vascular Endothelial Growth Factor A (VEGFA), a known splicing target of SRSF1. The Iso8a to Iso8b ratio: (i) increased in GBM biopsies with respect to UC (p-value < 0.00001); (ii) negatively correlated with the expression of circSMARCA5 (r-value = −0.46, p-value = 0.006); (iii) decreased in U87-MG overexpressing circSMARCA5 with respect to negative control (p-value = 0.0055). Blood vascular microvessel density, estimated within the same biopsies, negatively correlated with the expression of circSMARCA5 (r-value = −0.59, p-value = 0.00001), while positively correlated with that of SRSF1 (r-value = 0.38, p-value = 0.00663) and the Iso8a to Iso8b ratio (r-value = 0.41, p-value = 0.0259). Kaplan-Meier survival analysis showed that GBM patients with low circSMARCA5 expression had lower overall and progression free survival rates than those with higher circSMARCA5 expression (p-values = 0.033, 0.012, respectively). Our data convincingly suggest that circSMARCA5 is an upstream regulator of pro- to anti-angiogenic VEGFA isoforms ratio within GBM cells and a highly promising GBM prognostic and prospective anti-angiogenic molecule.
Emerging Molecular Technologies in Renal Cell Carcinoma: Liquid Biopsy
Authors: Cimadamore Alessia , Gasparrini Silvia , Massari Francesco , Santoni Matteo , Cheng Liang , Lopez-Beltran Antonio , Scarpelli Marina , Montironi Rodolfo
Published: February 2019

Liquid biopsy, based on the circulating tumor cells (CTCs) and cell-free nucleic acids has potential applications at multiple points throughout the natural course of cancer, from diagnosis to follow-up. The advantages of doing ctDNA assessment vs. tissue-based genomic profile are the minimal procedural risk, the possibility to serial testing in order to monitor disease-relapse and response to therapy over time and to reduce hospitalization costs during the entire process. However, some critical issues related to ctDNA assays should be taken into consideration. The sensitivity of ctDNA assays depends on the assessment technique and genetic platforms used, on tumor-organ, stage, tumor heterogeneity, tumor clonality. The specificity is usually very high, whereas the concordance with tumor-based biopsy is generally low. In patients with renal cell carcinoma (RCC), qualitative analyses of ctDNA have been performed with interesting results regarding selective pressure from therapy, therapeutic resistance, exceptional treatment response to everolimus and mutations associated with aggressive behavior. Quantitative analyses showed variations of ccfDNA levels at different tumor stage. Compared to CTC assay, ctDNA is more stable than cells and easier to isolate. Splice variants, information at single-cell level and functional assays along with proteomics, transcriptomics and metabolomics studies can be performed only in CTCs.
Contamination Particles and Plasma Etching Behavior of Atmospheric Plasma Sprayed Y2O3 and YF3 Coatings under NF3 Plasma
Authors: Song Je-Boem , Kim Jin-Tae , Oh Seong-Geun , Yun Ju-Young
Published: February 2019

Yttrium oxide (Y2O3) and yttrium oxyfluoride (YO0.6F2.1) protective coatings were prepared by an atmospheric plasma spraying technique. The coatings were exposed to a NF3 plasma. After the NF3 plasma treatment, the mass loss of the coatings showed that the etching rate of YO0.6F2.1 was larger than that of the Y2O3. X-ray photoelectron spectroscopy revealed that YO0.5F1.9 was present in the Y2O3 coating, whereas YO0.4F2.2 was present in the YO0.6F2.1 coating. Transmission electron microscope analysis conducted on contamination particles generated during the plasma etching showed that both coatings were mainly composed of YFx. The contamination particles estimated by in-situ particle monitoring sensor revealed that the YO0.6F2.1 compared with the Y2O3 coatings produced 65% fewer contamination particles.
Analysis of Fired Equipment within the Framework of Low-Cost Modelling Systems
Authors: Fialová Dominika , Jegla Zdeněk
Published: February 2019

Fired equipment suffers from local overloading and fouling of heat transfer surfaces, products are not of the required quality, and operating costs are increased due to the high pressure drop of process fluids. Such operational issues are affected by the non-uniform distribution of fluid flow and heat flux variability. Detailed numerical analyses are often applied to troubleshoot these problems. However, is this common practice effective? Is it not better to prevent problems from occurring by using quality equipment design? It is, according to the general consensus. Still, the experience of designing fired apparatuses reveals that the established standards do not reflect the real maldistribution sufficiently. In addition, as found from the given overview of modelling approaches, the radiant chamber and the convection section are usually analysed separately without significant continuity. A comprehensive framework is hence introduced. The proposed procedure clearly defines the interconnection of traditional thermal-hydraulic calculations and low-cost modelling systems for radiant and convection sections. A suitable combination of simplified methods allows for the reliable design of complex equipment and fast identification of problematic areas. The utilisation of selected low-cost models, i.e., the second phase of the systematic framework, is presented regarding the example of a steam boiler.
Environmental Life Cycle Assessment of Biogas as a Fuel for Transport Compared with Alternative Fuels
Authors: Lyng Kari-Anne , Brekke Andreas
Published: February 2019

Upgraded biogas, also known as biomethane, is increasingly being used as a fuel for transport in several countries and is regarded as an environmentally beneficial option. There are, nevertheless, few studies documenting the environmental impacts of biogas as a transport fuel compared with the alternatives on the market. In this study, life cycle assessment (LCA) methodology was applied to compare the environmental performance of biogas used as a fuel for bus transport with natural gas, electricity fueled buses, biodiesel, and fossil diesel. A sensitivity analysis was performed for the biogas alternative to assess the importance of the underlying assumptions. The results show that biogas has a relatively low contribution to the environmental impact categories assessed. Emissions of greenhouse gases are dependent on assumptions such as system boundaries, transport distances and methane leakages.
Improved Protocols of ITS1-Based Metabarcoding and Their Application in the Analysis of Plant-Containing Products
Authors: Omelchenko Denis O. , Speranskaya Anna S. , Ayginin Andrey A. , Khafizov Kamil , Krinitsina Anastasia A. , Fedotova Anna V. , Pozdyshev Denis V. , Shtratnikova Viktoria Y. , Kupriyanova Evgenia V. , Shipulin German A. , Logacheva Maria D.
Published: February 2019

Plants are widely used for food and beverage preparation, most often in the form of complex mixtures of dried and ground parts, such as teas, spices or herbal medicines. Quality control of such products is important due to the potential health risks from the presence of unlabelled components or absence of claimed ones. A promising approach to analyse such products is DNA metabarcoding due to its high resolution and sensitivity. However, this method’s application in food analysis requires several methodology optimizations in DNA extraction, amplification and library preparation. In this study, we present such optimizations. The most important methodological outcomes are the following: (1) the DNA extraction method greatly influences amplification success; (2) the main problem for the application of metabarcoding is DNA purity, not integrity or quantity; and (3) the “non-amplifiable” samples can be amplified with polymerases resistant to inhibitors. Using this optimized workflow, we analysed a broad set of plant products (teas, spices and herbal remedies) using two NGS platforms. The analysis revealed the problem of both the presence of extraneous components and the absence of labelled ones. Notably, for teas, no correlation was found between the price and either the absence of labelled components or presence of unlabelled ones; for spices, a negative correlation was found between the price and presence of unlabelled components.
Reduced Exertion High-Intensity Interval Training is More Effective at Improving Cardiorespiratory Fitness and Cardiometabolic Health than Traditional Moderate-Intensity Continuous Training
Authors: Cuddy Tom F. , Ramos Joyce S. , Dalleck Lance C.
Published: February 2019

This study sought to determine the effectiveness of an 8 wk reduced-exertion high-intensity interval training (REHIT) at improving cardiorespiratory fitness (CRF) and positively modifying cardiometabolic health in the workplace environment. Participants (n = 32) were randomized to two groups: (1) One group (n = 16) was prescribed an 8 wk REHIT program, and (2) one group (n = 16) was prescribed moderate-intensity continuous training (MICT). Cardiometabolic risk factors and CRF were measured at baseline and 8 wks. After 8 wks, changes in CRF (REHIT, 12%; MICT, 7%), systolic blood pressure (REHIT, −5%; MICT, −2%), waist circumference (REHIT, −1.4%; MICT, −0.3%), and metabolic syndrome (MetS) severity (MetS z-score: REHIT, −62%; MICT, 27%) were more favorable (p < 0.05) in the REHIT group relative to the MICT group. Interestingly, there was a significantly greater proportion of participants in the REHIT group (75%, 9/12) who had a favorable change in the MetS z-score (Δ > −0.60) relative to the MICT group (47%, 7/15). The main finding of the present study is that 8 wks REHIT elicited more potent and time-efficient improvements in CRF and cardiometabolic health when compared to traditional MICT. This study provides critical evidence for implementation of the sprint interval training (SIT) paradigm from the scientific literature into a real-world workplace setting.
Melatonin: A Small Molecule but Important for Salt Stress Tolerance in Plants
Authors: Zhan Haoshuang , Nie Xiaojun , Zhang Ting , Li Shuang , Wang Xiaoyu , Du Xianghong , Tong Wei , Song Weining
Published: February 2019

Salt stress is one of the most serious limiting factors in worldwide agricultural production, resulting in huge annual yield loss. Since 1995, melatonin (N-acetyl-5-methoxytryptamine)—an ancient multi-functional molecule in eukaryotes and prokaryotes—has been extensively validated as a regulator of plant growth and development, as well as various stress responses, especially its crucial role in plant salt tolerance. Salt stress and exogenous melatonin lead to an increase in endogenous melatonin levels, partly via the phyto-melatonin receptor CAND2/PMTR1. Melatonin plays important roles, as a free radical scavenger and antioxidant, in the improvement of antioxidant systems under salt stress. These functions improve photosynthesis, ion homeostasis, and activate a series of downstream signals, such as hormones, nitric oxide (NO) and polyamine metabolism. Melatonin also regulates gene expression responses to salt stress. In this study, we review recent literature and summarize the regulatory roles and signaling networks involving melatonin in response to salt stress in plants. We also discuss genes and gene families involved in the melatonin-mediated salt stress tolerance.
Clinical Importance of Placental Testing among Suspected Cases of Congenital Zika Syndrome
Authors: Seferovic Maxim D. , Turley Michelle , Valentine Gregory C. , Rac Martha , Castro Eumenia C. C. , Major Angela M. , Sanchez Brianna , Eppes Catherine , Sanz-Cortes Magdalena , Dunn James , Kautz Tiffany F. , Versalovic James , Muldrew Kenneth L. , Stout Timothy , Belfort Michael A. , Demmler-Harrison Gail , Aagaard Kjersti M.
Published: February 2019

Contemporaneous Zika virus (ZIKV) strains can cause congenital Zika syndrome (CZS). Current ZIKV clinical laboratory testing strategies are limited and include IgM serology (which may wane 12 weeks after initial exposure) and nucleic acid testing (NAT) of maternal serum, urine, and placenta for (+) strand ZIKV RNA (which is often transient). The objectives of this study were to determine if use of additional molecular tools, such as quantitative PCR and microscopy, would add to the diagnostic value of current standard placental ZIKV testing in cases with maternal endemic exposure and indeterminate testing. ZIKV RNA was quantified from dissected sections of placental villi, chorioamnion sections, and full cross-sections of umbilical cord in all cases examined. Quantitation with high-resolution automated electrophoresis determined relative amounts of precisely verified ZIKV (74-nt amplicons). In order to localize and visualize stable and actively replicating placental ZIKV in situ, labeling of flaviviridae glycoprotein, RNA ISH against both (+) and (−) ZIKV-specific ssRNA strands, and independent histologic examination for significant pathologic changes were employed. We demonstrate that the use of these molecular tools added to the diagnostic value of placental ZIKV testing among suspected cases of congenital Zika syndrome with poorly ascribed maternal endemic exposure.
Corrosion Characteristics of Copper-Added Austempered Gray Cast Iron (AGCI)
Authors: Seikh Asiful H. , Sarkar Amit , Singh Jitendra Kumar , Mohammed Sohail M. A. Khan , Alharthi Nabeel , Ghosh Manojit
Published: February 2019

The aim of this investigation was to assess the corrosion behavior of gray cast iron (GCI) alloyed with copper. Alloyed GCI specimens were austempered isothermally at varying temperatures. After austenitizing at 927 °C, the samples were austempered at different temperatures ranging from 260 to 385 °C with an interval of 25 °C for 60 minutes. As a result, these samples developed an ausferrite matrix with different percentages of austenite. The resulting microstructures were evaluated and characterized by optical microscope (OM), scanning electron microscope (SEM), and X-ray diffraction (XRD). The corrosion characteristics were determined using potentiodynamic polarization tests and electrochemical impedance spectroscopy (EIS) of these samples. These tests were carried out in a medium of 0.5 M H2SO4 and 3.5% NaCl solution. It was observed from the potentiodynamic polarization results that with increasing austempering temperature, the corrosion rate decreased. All results of the EIS were in accordance with a constant phase element (CPE) model. It was found that with an increase in austempering temperature, the polarization resistance (Rp) increased. The austenite content was also found to influence the corrosion behavior of the austempered gray cast iron (AGCI).