bluuebunny/crossref_metadata_2025 huggingface dataset:
Scalable One-Pot - Liquid-Phase Oligonucleotide Synthesis for Model Network Hydrogels
Authors: Creusen Guido , Oluwadunsin Akintayo Cecilia , Schumann Katja , Walther Andreas
Published: May 2020

Solid-phase oligonucleotide synthesis (SPOS) based on phosphoramidite chemistry is currently the most widespread technique for DNA and RNA synthesis, but suffers from scalability limitations and high reagent consumption. Liquid-phase oligonucleotide synthesis (LPOS) uses soluble polymer supports and has the potential of being scalable. However, at present, LPOS requires 3 separate reaction steps and 4-5 precipitation steps per nucleotide addition. Moreover, long acid exposure times during the deprotection step degrade sequences with high A-content (adenine) due to depurination and chain cleavage. In this work, we present the first one-pot liquid-phase DNA synthesis technique, which allows the addition of one nucleotide in a one-pot reaction of sequential coupling, oxidation and deprotection, followed by a single precipitation step. Furthermore, we demonstrate how to suppress depurination during the addition of adenine nucleotides. We showcase the potential of this technique to prepare high-purity 4-arm PEG‑T20 (T = thymine) and 4-arm PEG-A20building blocks in multi-gram scale. Such complementary 4-arm PEG-DNA building blocks reversibly self-assemble into supramolecular model network hydrogels, and facilitate the elucidation of bond lifetimes. These model network hydrogels exhibit new levels of mechanical properties, high stability at room temperature (melting at 44 ‎°C), and thus open up pathways to next-generation, scalable DNA-materials programmable through sequence recognition and available for macroscale applications.
Low Pressure Gas Electron Diffraction: an Experimental Setup and Case Studies
Authors: Vishnevskiy Yury , Blomeyer Sebastian , Reuter Christian G.
Published: May 2020

Principles of low pressure gas electron diffraction(LPGED) are introduced. An experimental setup hasbeen constructed for measuring electron diffraction patterns of gaseous samples at pressures below 10−3mbar. Test measurements have been performed for benzoic acid at T = 287 K corresponding to a vapor pressure of the substance P = 2 × 10−4 mbar, for iodoform CHI3 at T = 288 K (P = 4 × 10−4 mbar) and for carbon tetraiodide CI4 at T = 290K (P = 1 × 10−4 mbar). Due to the low experimental temperature thermal decomposition of CI4 has been prevented, which was unavoidable in previous classical measurements at higher temperatures.From the obtained data the molecular structures have been successfully refined. The most importantsemi-empirical equilibrium molecular parameters are re(Car–Car)av = 1.387(5) Å in benzoic acid, re(C–I)= 2.123(3) Å in iodoform and re(C–I) = 2.133(7) Å in carbon tetraiodide. The determined parametersshowed consistency with theoretically predicted values. A critical comparison with results of the earlierinvestigations has also been done.
Resolving the Complexity of Spatial Lipidomics with MALDI Trapped Ion Mobility Spectrometry
Authors: Djambazova Katerina , Klein Dustin R. , Migas Lukasz , Neumann Elizabeth , Rivera Emilio , Van de Plas Raf , Caprioli Richard M. , Spraggins Jeffrey
Published: May 2020

Lipids are a structurally diverse class of molecules, with important biological functions including cellular signaling and energy storage. Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) allows for visualization of molecules directly from tissue, but has difficulty addressing the structural diversity of the lipidome, owing to the presence of many isobaric and isomeric species that overlap in m/z space. Integrating ion mobility separations aids in mass spectral deconvolution and address lipid complexity. Here we demonstrate that a MALDI quadrupole time-of-flight (QTOF) mass spectrometer with trapped ion mobility spectrometry (TIMS) enables a significant increase in the peak capacity (~207%) during lipid IMS experiments. MALDI-TIMS was also used for separation of lipid isomer standards, including sn-backbone isomers, acyl chain isomers, as well as double bond positional and geometric isomers was also demonstrated. Proof of concept, in situ separation and imaging of lipid isomers with distinct spatial distributions was demonstrated using whole-body mouse pup tissue.
Discovery of Record-Breaking Metal-Organic Frameworks for Methane Storage using Evolutionary Algorithm and Machine Learning
Authors: Lee Sangwon , Kim Baekjun , Kim Jihan
Published: May 2020

In the past decade, there has been a rise in a number of computational screening works to facilitate finding optimal metal-organic frameworks (MOF) for variety of different applications. Unfortunately, most of these screening works are limited to its initial set of materials and result in brute-force type of a screening approach. In this work, we present a systematic strategy that can find materials with desired property from an extremely diverse and large MOF set of over 100 trillion possible MOFs using machine learning and evolutionary algorithm. It is demonstrated that our algorithm can discover 964 MOFs with methane working capacity over 200 cm3 cm−3 and 96 MOFs with methane working capacity over 208 cm3 cm−3, which is the current world record. We believe that this methodology can facilitate a new type of a screening approach that takes advantage of the modular nature in MOFs, and can readily be extended to other important applications as well.
A Study on Oxidative stress and antioxidant status in Diabetic nephropathy
Authors: Gurupavan kumar Ganta1  , Kedari G S R
Published: May 2020

Diabetes mellitus is the most common metabolic disorder in the world. The metabolic dysregulation of diabetes mellitus affects multiple organs like Kidneys, nerves, eyes and heart. Worldwide Among all diabetics, 20-40% of the people are suffering from Diabetic Nephropathy. Oxidative stress is increased by hyperglycemia in which Reactive Oxygen Species has been implicated in the pathology of these complications. The aim of our present study is one such attempt to find the role of oxidative stress by estimating the levels of oxidants and anti oxidant levels in diabetic nephropathy in ethnic south Indian population. 30 diagnosed cases of diabetic Nephropathy  were taken as cases and 30 age and sex matched Type 2 Diabetes mellitus patients were included as controls in the study. For oxidant levels Malondialdehyde (MDA) was estimated and for anti oxidant levels Super oxide Dismutase (SOD), Glutathione Peroxidase (GPx), Glutathione Reductase (GR) were measured. Statistically significant increase is observed in the levels of Malondialdehyde in cases when compared to controls. There is no statistical significant difference in the levels of Superoxide dismutase and Glutathione peroxidase between cases and controls. Whereas statistical significant difference is observed in the levels of Glutathione reductase in Diabetic Nephropathy cases when compared with controls.
APRESIASI SASTRA SISWA SEKOLAH DASAR DI KOTA SORONG
Authors: NFN Muntihanah
Published: May 2020

This paper aims to measure appreciation level of Grade V students in Sorong toward literaturengThis measurement uses Criterion Reference Assesment (CRA) approach beside Direct Evaluation of Literature and Indirect Evaluation of Literature. The result shows that on the whole appreciation level of literature of the Grade V students in Sorong Municipality is in  Less Grade with mean score 54.64.Particularly, Indirect Appreciation Level of Literature got much lower score by mean score 37.13. Meanwhile, Direct Appreciation Level got better level with predicate Satisfatory by mean score 62.77.  Keywords: literature appreciation, Criterion Reference Assesment (CRA),direct literature appreciation, indirect literature appreciation.  AbstrakPenelitian ini bertujuan untuk mengukur tingkat apresiasi sastra siswa  kelas V SD di Kota Sorong. Pengukuran dilakukan dengan pendekatan penilaian acuan kriteria (PAK) dan penilaian sastra langsung dan penilaian sastra tidak langsung. Hasilnya menunjukkan bahwa secara keseluruhan tingkat apresiasi sastra siswa kelas V SD Kota Sorong berada pada predikat Kurang dengan capaian nilai rata-rata 54.64. Secara lebih khusus, tingkat apresiasi sastra tidak langsung jauh lebih rendahdengan capaian nilai rata-rata 37.13, meskipun sama-sama berada pada predikat Kurang. Sementara itu, tingkat apresiasi sastralangsung sedikit lebih baik karena berada pada predikat Cukup dengan capaian nilai rata-rata 62,77. Kata kunci: apresiasi sastra, penilaian acuan kriteria, apresiasi sastra langsung,  apresiasi sastra tidak langsung
How to Integrate Ideological and Political Education into Mathematics Course of Vocational Education
Authors: Tian Guijuan
Published: May 2020

With the increasing enrollment of general higher vocational colleges every year, the inconsistency between the knowledge level and ability of the enrolled students and ideological and political education hinders the realization of the teaching purpose of the school to a great extent. Advanced mathematics is a compulsory basic course for college students and an important subject for realizing the teaching purpose. In order to achieve the teaching purpose and improve the teaching quality and level of mathematics in higher vocational colleges, we must deepen the reform of teaching contents in advanced mathematics courses in colleges, and integrate mathematical knowledge with ideological and political education organically, giving full play to the teaching characteristics of advanced mathematics courses while fulfilling the ideological and political education for students. Moreover, ideological and political education is also combined with interactive advantages by means of interactive teaching. This paper briefly discusses how to integrate advanced mathematics course with ideological and political education. By analyzing the actual teaching cases of ideological and political education and advanced mathematics courses, the content of classroom teaching is discussed.
A Study on the Dilemma of Contemporary Teachers' Moral Life
Authors: Li Zhaojing
Published: May 2020

The essence of teachers is to live a moral life with students and create a possible moral life together. At present, the alienation of teachers' moral life has reached an amazing degree. Based on this, at the conceptual level, rediscover the emotional dimension of teachers' moral life in a humanistic way and turn to the inner power of teachers' emotional life. At the practical level, it emphasizes the cultivation of emotional quality of moral life.
A Contrastive Study of Anaphora in English and Chinese
Authors: Jia Simo
Published: May 2020

Recently, there has been growing interest in the study on cohesion of texts, particularly in the aspect of anaphoric reference. The problem under discussion is within the scope of similar and different usages of anaphors in English and Chinese. Although much work has been done, more studies need to be conducted to ascertain the convincingness of the theories. This essay will demonstrate language materials in real situation in English text and its Chinese translations to prove, explain and enrich the theories about the distinction of English and Chinese anaphora. The thesis for this essay is the contrastive study of anaphora between English and Chinese texts that is the dissimilarities of anaphora in these two language texts and discuss the reasons that caused these differences. And for arguments, four cases of Han’s Andersen’s fairy tales and their Chinese translations and one example from New Oxford Dictionary are selected for the purpose. For methodology, quality analysis is employed. But in general, it is to compare and to contrast in the light of Halliday’s theory on cohesion. The way adopted is to compare broad wise, which means to list similarities and dissimilarities of things needed to be contrast -- anaphora in English and Chinese texts, and then conducts further analysis on them with the theoretical framework. In aspect of detailed analysis, the author adopts the way of illustration, combining language phenomenon listed above with arguments.
The Application of HTP Projection Test in the Psychological Survey of Tibetan and Han College Students
Authors: Xu Hua , Liu Qiyu , Yuzhen Deji
Published: May 2020

The projective test is not only helpful to find the potential psychological crisis, but also to overcome the language barrier and make up for the deficiency of the questionnaire test to a certain extent.In this study, 403 college students (205 Tibetan students and 198 Han students) from a national college were selected to test their mental health with Symptom Checklist-90 (SCL-90) and House-Tree-Person test (HTP).By comparing the results of questionnaire test and drawing projection test, it is found that SCL-90 and HTP test are significantly related to the positive screening results of four factors: Somatization, Depression, Anxiety and Phobic Anxiety. Both HTP test and SCL-90 test results show that the scores of Somatization, Depression, Anxiety and Phobic Anxiety of Tibetan and Han college students were significantly different; the scores of Anxiety and Phobic Anxiety of different gender college students were significantly different. Using HTP test as a supplementary test of questionnaire test can effectively improve the accuracy of screening.
Analysis of Dove's Brand Communication Strategy in the Chinese Market
Authors: Du Junyan
Published: May 2020

DOVE is one of the chocolate brands launched by MARS in China. For more than ten years since DOVE entered the Chinese market, she has continuously adjusted her marketing model to conform to the Chinese market and has become more and more popular with Chinese people. Her unique advertising model and fresh advertising style have formed a deeper brand impression in consumers ’hearts generated by brand loyalty. This article mainly explores DOVE’s brand communication strategy in China from the marketing communication in DOVE ’s overall brand marketing, and studies how DOVE, as a foreign brand, adapts to the local market and gains the first position in the market. DOVE serves as a leader for Chinese chocolate businesses to step out of difficulty and provideshelpful reference experience for China's multinational enterprises to survive in the context of global economy.
Analisis Laporan Akuntabilitas Kinerja Instansi Pemerintahan Dinas Kebudayaan, Pariwisata, Pemuda dan Olahraga Kabupaten Kubu Raya
Authors: Putri Beby Nurtesha
Published: May 2020

The purpose of this study was to find out about performance measurement in the Department of Culture, Tourism, Youth and Sports of Kubu Raya Regency. Performance measurement is carried out by the Government Agency Performance Accountability Report in accordance with Presidential Instruction No. 7 of 1999. Performance measurement is used as a basis for assessing failure program efficacy and execution and activities according to targets and objectives set in realizing the vision and mission of the Regency Government. The research method used in this research is descriptive method. Data obtained, then interpreted and analyzed, so that it can provide information that can be used to solve the problem at hand. The type of data used is secondary and primary data. The results of the study show performance for all existing targets and in accordance with the expected conditions. Suggestions the government needs to establish a standard reference in preparing reports.

Keywords: Accountability, Agency Performance Accountability Report
Analisis Potensi Kecurangan Dalam Pengelolaan Keuangan Desa (Studi: Desa Kesongo, Kecamatan Tuntang, Kabupaten Semarang, Jawa Tengah)
Authors: Alfaruqi Ismail , Kristianti Ika
Published: May 2020

Indonesia Corruption Watch (ICW) found 154 corruption cases during 2015-2017, most of them were corruption cases involving the village budget. The potential for fraud can be detected by cheating triangle theory, namely pressure, opportunity and rationalization. The purpose of this study is to identify potential fraud in village financial management. This study uses a qualitative approach and the type of data used is primary data obtained directly using interview techniques from the village financial management process conducted by the Village Financial Management Technical Officer (PTPKD) Kesongo Village, Tuntang District, Semarang Regency. The results of the study show that in the village financial management in Kesongo Village there is potential for fraud including: the necessity to do something; disciplinary behavior; feel that they are not detrimental to others and consider mistakes to be natural and often occur. This study concluded that in Kesongo Village there was potential for fraud in the process of village financial management.

Keywords: Village Financial Management, Village Apparatus, Potential for Fraud, Control
Pemeriksaan Operasional Atas Aktivitas Penjualan Pada Hotel Alqueby Untuk Menilai Efektivitas Penjualan
Authors: Regawa Joey Giovanni
Published: May 2020

Alqueby Hotel gets profit from renting rooms, restaurant, swimming pool tikets, and gym. Protif is needed so that the hotel can continue to run its operations. Sales activity is the primary activity in the hotel. An ineffective sales activities can cause lack of profit or even losses. So that, writer interested to do operational review on sales activity at Alqueby Hotel. Operational review is a process to analize operational activity to evaluate economic, efficient, and effective from all operation activity in the organization. Method that used in this research is descriptive method. The dependent variable in this research is effectivity, while the independent variable in this research is sales. Data for this research was obtained from two resource, primary resource was obtained through observation to Alqueby Hotel, interview with director, CEO, sales and marketing executive, front office, internal control questionaire, while secondary resource was obtained through organization structure of Alqueby Hotel, job description, income statement Alqueby Hotel, and document that used in sales activity Alqueby Hotel. To overcome those complication, writer gave several recommendation to Alqueby Hotel which is, CEO should allocate tasks with director, Alqueby Hotel should recruit marketing staff and make strategy marketing and plan marketing cost.

Keywords: Operational Review, Sales Activity, Effectivity on Sales
Perancangan Sistem Penjadwalan Dan Pengontrolan Produksi Perusahaan Padupadan
Authors: Marsheilla Marsheilla , Marsheilly Marsheilly
Published: May 2020

The development of garment industry, especially for export, may bring certain challenges to Micro Small and Medium Enterprises (MSME). The company that export its products has to handle its production carefully, in particular for the export deadline. When the company fail to deliver its products on time, a high amount of fine, approximately 30% of total production cost, will be faced. Padupadan is a garment focusing on local product. To be competitive, it needs to improve its quality in both scheduling and production control. Orders has been accepted without actual information status of running order which cause delay and low product quality. Due to that situation, this company needs a system that assist decision making relating to controlling orders and performance of any parties in production process.Case study was used as method of this explanatory research. Data were analyzed using MIT 90’s Framework and Data Flow Diagram. Design of Padupadan production system is related with 9 analyzed activities, namely marketing, sales order, production scheduling, human resource management, purchasing, receiving, warehouse (raw material), production, and warehouse (finished goods) which will be structured and standardized for the company. This system provides assistance in determining production scheduling target, system to control production that will help owner in evaluating employees, performance of production department and categorized supplier. Owner provides positive respon on the design since it can assist the company for future advance.

Keywords: Scheduling System Control; Production Control
Pengaruh Investasi Asing dan Investasi Dalam Negeri Terhadap Perekonomian Indonesia
Authors: Kambono Herman , Marpaung Elyzabet Indrawati
Published: May 2020

Abstract

This study aims to analyze the effect of Foreign Investment and Domestic Investment on the Indonesian Economy. The data used is Indonesian macroeconomic time series data. In the next stage, the analysis was carried out using quantitative methods including: Ordinary Least Square (OLS) Regression Method with Multiple Regression models, and the Coefficient ofDetermination (R2).As for the results of this study later, it can be seen how much influence the independent variable has on the dependent variable. And how big is the percentage of the variation of the independent variable to the dependent variable or the dependent variable

 

Keywords: Domestic Investment, Foreign Investment and the Economy Indonesia.

 

Abstrak

Penelitian ini bertujuan untuk menganalisis pengaruh Investasi Asing dan Investasi Dalam Negeri terhadap Perekonomian Indonesia. Data yang digunakan adalah data time series makro ekonomi Indonesia. Pada tahap selanjudnya, analisis dilakukan dengan menggunakan metode kuantitatif antara lain: Metode Regresi Ordinary Least Square (OLS) dengan model Regresi Berganda (Multiple Regression), dan Koefisien Determinasi (R2).Adapun hasil dari penelitian ini nantinya, dapat dilihat seberapa besar pengaruh variable bebas terhadap variable tidak bebasnya. Dan seberapa besar prosentasi variasi variable bebas terhadap variable terikat atau variable tidak bebasnya.

Kata Kunci: Investasi Dalam Negeri, Investasi Luar Negeri dan Perekonomian Indonesia
Sebuah Solusi dari Para Mahasiswa dan Dosen Akuntansi untuk Perkembangan UMKM di Indonesia
Authors: Sanggrama Erlangga Budi , Rachmat Rhaisya Setiawati , Se Tin Se Tin
Published: May 2020

Unit usaha mikro, kecil, dan menengah tidak dapat diremehkan dalam kontribusinya terhadap perekonomian khususnya di Indonesia. UMKM secara keseluruhan merupakan media penyerapan tenaga kerja yang besar dengan kontribusi yang tidak sedikit terhadap produk domestik bruto. Namun masih terdapat tantangan bagi UMKM dalam mengembangkan bisnisnya beberapa diantaranya adalah dalam keterbatasan modal atau pinjaman dan pengelolaan aset unit usaha yang belum tertib.

Memiliki sistem pembukuan yang komprehensif adalah salah satu solusi untuk mengatasi kedua masalah tersebut karena akan membuat unit usaha lebih kredibel di mata lembaga keuangan dan unit usaha pun memiliki informasi yang lebih lengkap atas posisi asset mereka sehingga pengambilan keputusan bisnis akan lebih baik. Sayangnya sumber daya yang diperlukan untuk memiliki sistem pembukuan yang komprehensif cukup rumit dan biasanya tidak menjadi prioritas unit usaha.

Tulisan ini menghadirkan sebuah solusi untuk membantu perkembangan UMKM dengan membentuk lembaga khusus yang terdiri dari dosen dan mahasiswa akuntansi universitas yang secara berkelanjutan mengabdikan diri kepada UMKM untuk menciptakan dan mengelola sistem pembukuan yang komprehensif.
Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats
Authors: DOĞAN Abdulahad , DÖNMEZ Fatih , ANUK Özgür Ozan
Published: May 2020

The aim of this study was to evaluate the protective effects of the leaf infusion of chinar (Platanus orientalis L.) on erythrocyte fragility, haematological parameters and antioxidant status against ethanol-induced oxidative stress in rats. Thirty male rats were divided into five groups: Control, Ethanol, Ethanol+Silymarin (10 mg kg-1), Ethanol+PO-20 mg mL-1 infusion, and Ethanol+PO-60 mg mL-1 infusion. According to the results, in the Ethanol group, erythrocyte counts, red cells distribution, plateletcrit, platelet and lymphocyte levels significantly decreased compared to the Control group, while PO-60 dose-fed group showed a significant increase in haematocrit and haemoglobin values compared to the Ethanol group. There were significant changes in erythrocyte fragility of Ethanol and Ethanol-treatment groups at different NaCl concentrations of 0.3 and 0.6 according to Control group. It was observed that PO Leaf infusion reduced the hemolysis caused by ethanol at a concentration of 0.3% NaCl, thus reducing the values to the control values. In addition, PO leaf infusion caused a significant increase in total antioxidant status against ethanol toxicity and a significant decrease in total oxidative status and oxidative stress index. It was concluded that PO leaf infusion may have antihematotoxic effect, reducing erythrocyte fragility and increase antioxidant capacity against ethanol toxicity.
A Abordagem Temática Caracterizada por Pesquisadores da Área de Ensino de Ciências
Authors: Magoga Thiago Flores , Muenchen Cristiane
Published: May 2020

Entendida como uma perspectiva curricular que tem por base o trabalho a partir de temas, a Abordagem Temática vem sendo sinalizada pela literatura da área como possibilidade para a problematização de alguns desafios relacionados ao processo educacional. O presente artigo é recorte de uma pesquisa mais ampla e objetiva discutir características das ações de um coletivo de pesquisadores que têm construído e disseminado conhecimento sobre essa perspectiva. O coletivo de pesquisadores foi delimitado por meio de um processo de revisão bibliográfica, realizado à luz da epistemologia de Fleck, nos principais períodicos da área de ensino de ciências. Dessa forma, após a realização de entrevistas com cinco professores/pesquisadores da área de ensino de ciências, os quais têm como similaridade a formação inicial em Física, perceberam-se características comuns em relação às suas ações via Abordagem Temática. Essas características foram organizadas e apresentadas a partir de três categorias, emergidas do processo da Análise Textual Discursiva. Após a apresentação e discussão de cada uma dessas categorias e de suas respectivas sub-categorias, sinaliza-se a importância que essas possuíram para a identificação dos modos de pensar e agir do coletivo de professores/pesquisadores, possibilitando a compreensão de como a Abordagem Temática vem sendo disseminada dentro da área.
Isolation and Characterization of Red Bean and Green Bean Protein using the Extraction Method and Isoelectric pH
Authors: Kusumah Slamet Hadi , Andoyo Robi , Rialita Tita
Published: May 2020

Stunting children need food intake with higher protein and essential amino acids such as lysine and leucine than normal children. Red Beans (Phaseolus Vulgaris L.) and Green Beans (Phaseolus Radiatus L.) have protein content, respectively 22.07 ± 0.13% and 19.99 ± 0.07%, and are rich in essential amino acids lysine and leucine needed by a stunting child. The Development of food products with high protein concentrations (high protein food) such as isolates/protein concentrates is an important subject that must be done. This study aims to determine the technique of isolating red bean and green bean protein through extraction and deposition methods at isoelectric pH. The research method used is an experimental method with descriptive data analysis. Identification of isoelectric pH of red bean and green bean protein is done through electrophoretic mobility (cm2/Vs) testing on samples that have been conditioned at 3 different depositional pHs namely pH 3.00, 4.00, and 5.00. The results showed the isoelectric pH value of red bean and green bean protein, namely pH 4.56 and pH 4.81 respectively, where the pH had electrophoretic mobility values equal to zero. The process of isolating red bean and green bean protein produces protein powder with a protein content of 79.22 ± 0.06% and 80.69 ± 0.06%, respectively. Based on the weight yield, red bean and green bean protein concentrate powder had a yield of 14.88% and 16.75%, respectively.
Epidemiology and outcomes of ischemic stroke treatment in two public hospitals of Campos dos Goytacazes, RJ.
Authors: Renon Talles Falqueto , Maia Samara Oliveira , Louvain de Souza Thais , De Abreu Annelise Maria de Oliveira Wilken , Vandesteen Leonardo
Published: May 2020

Background: The main origin of functional dependence in Brazil and the world is the ischemic stroke. The early thrombolytic treatment reduces this morbidity. However, the extended in-hospital delay is the main risk factor for the suboptimal number of ischemic stroke patients who receive this treatment. Objective: To describe the management of patients admitted with ischemic stroke in two Brazilian public hospitals. Methods: This cross-sectional study was carried out in two emergency units in 2016 in Campos dos Goytacazes: Hospital Ferreira Machado (HFM) and Hospital Geral de Guarus (HGG). We analyzed the prevalence of sex, age, risk factors, time of first symptoms, prescription of thrombolytic therapy and contraindications to its use. Results: None of the 130 patients with ischemic stroke received a prescription of rt-PA, even though HFM had rt-PA available throughout the period of the study. HGG does not keep this data documented. Of all, 41 patients died (31,54%). Advancing age (p < 0.0005) and atrial fibrillation 3.458 (CI = 95%, 1.239 to 10.16, p = 0.0238) were risks factors for the mortality in this population. Conclusions: The lack of information in medical records reveals that low staff training may be the main reason why thrombolytic therapy was not prescribed. The elevated mortality rate shows that medical care for patients admitted with ischemic stroke in our region is far from ideal.
OCORRÊNCIA DE POLIFARMÁCIA EM IDOSOS EM HOSPITAL DIA GERIÁTRICO
Authors: Tiago Daniela Cristina , Rodrigues Bráulio Brandão , Lopes Nathália Ramos , Alvarenga Lara Cristina Rocha , De Lima Diogo Teles , De Medeiros Luis Mário Mendes , De Oliveira Julia Maria Rodrigues
Published: May 2020

O presente estudo tem por objetivo avaliar a ocorrência de polifarmácia em idosos assistidos pelo Hospital Dia do Idoso (HDI) de Anápolis, Goiás. A pesquisa é quantitativa descritiva com delineamento transversal com 551 idosos do HDI, entre os meses de outubro de 2015 a janeiro de 2016. A amostra é composta por idosos atendidos na Clínica Médica do Hospital Dia do Idoso (HDI). Os dados foram coletados a partir dos prontuários de pessoas com 60 anos ou mais e que estavam cadastrados na unidade. As variáveis estudadas foram sexo, idade, mês do atendimento, número de medicamentos utilizados e quais destes se classificavam como potencialmente inapropriados, segundo o critério de Beers-Fick. A análise foi feita com o programa Statistical Package for the Social Sciences (SPSS). Entre os idosos que frequentam essa unidade de saúde 70,4% são mulheres e 29,6% homens. Destes, 38,8% usam cinco ou mais medicamentos, ou seja, são classificados em polifarmácia. Além disso, constatou-se uma tendência a aumentar o número de medicamentos utilizados à medida que a idade avança.  Ao adotar os Critérios de Beer-Fick, observou-se que 21,0% utilizavam medicamentos potencialmente inapropriados e 20,3% utilizavam medicamentos não recomentados. Dentre estes se destacam os Bloqueadores dos Canais de Cálcio por serem os mais utilizados. Os idosos do Hospital Dia do Idoso seguem as tendências encontradas na literatura, embora apresentem uma maior porcentagem de polifarmácia. Achado que se baseia no fato da amostra estar localizada em um centro de atendimento exclusivo a idosos.
Manajemen Panen Kelapa Sawit (Elaeis guineensis Jacq.) di Kebun Hatantiring, Kalimantan Tengah
Authors: Situmorang Antonio C , Zaman Sofyan , Junaedi Ahmad
Published: May 2020

Kegiatan magang memberikan ilmu dan keterampilan dalam budidaya kelapa sawit baik secara teknis maupun manajerial. Kegiatan magang dilaksanakan mulai bulan Februari hingga Juni 2014 di kebun Hatantiring, Kalimantan Tengah. Aspek pemanenan mencakup rotasi panen, taksasi produksi, sistem panen, pengawasan terhadap kehilangan hasil (losses), dan produktivitas. Pengamatan diuji dengan analisis uji t student dan analisis uji LSD. Berdasarkan analisis uji t diketahui bahwa rotasi panen terlambat akan menambah persentase brondolan sehingga peluang kehilangan hasil (losses) juga akan meningkat. Berdasarkan uji LSD pada pemeriksaan losses pertama dan kedua menunjukkan hasil signifikan begitu juga pada pemeriksaan kedua dan ketiga. Hal ini menunjukkan bahwa arahan dan pengawasan mampu meingkatkan kesadaran karyawan panen dalam menekan losses. Peningkatan produksi juga dapat dicapai dengan melakukan sistem panen yang lebih efektif dan efisien. Sistem panen DOL C1R2 dinilai lebih efektif dan efisien dari pada sistem panen DOL C1R1 karena output pemanen mengalami peningkatan. Hal ini berpengaruh terhadap bertambahnya pendapatan karyawan dan pengurangan jumlah karyawan.
Pengaruh Aplikasi Giberelin Pada Padi Sawah (Oryza Sativa L.)Varietas Hibrida (Hipa Jatim 2) dan Varietas Unggul Baru (Ciherang)
Authors: Utama Rizqi Caesar , Sugiyanta .
Published: May 2020

Penelitian ini bertujuan untuk mempelajari pengaruh pemberian zat pengatur tumbuh giberelin terhadap produksi padi varietas hibrida (Hipa Jatim) dan varietas unggul baru (Ciherang). Penelitian ini dilaksanakan di Desa Karawang Wetan, Kecamatan Karawang Timur, Kabupaten Karawang, Jawa Barat pada bulan November sampai April 2014. Rancangan percobaan yang digunakan adalah adalah rancangan acak kelompok (RAK) Split Plot 2 faktor yaitu varietas sebagai petak utama dan dosis giberelin sebagai anak petak.Varietas yang digunakan yaitu Hipa Jatim 2 dan Ciherang. Dosis giberelin yang digunakan adalah 5.6 g ha-1, 8 g ha-1, 11.2 g ha-1, 16.8 g ha-1, 22.4 g ha-1, dan kontrol (tanpa aplikasi giberelin). Pengamatan yang diamati yaitu pertumbuhan tanaman, biomassa padi, komponen hasil dan hasil. Hasil penelitian menunjukkan bahwa secara umum varietas Hipa Jatim 2 menunjukkan pertumbuhan tanaman lebih tinggi dibandingkan varietas Ciherang, tetapi varietas Ciherang mempunyai komponen hasil, biomassa padi, GKP dan GKG lebih tinggi dibandingkan varietas Hipa Jatim 2. Giberelin dengan dosis 22.4 g ha-1 secara umum menghasilkan komponen biomassa padi yang lebih tinggi daripada pemberian dosis lainnya. Hasil penelitian ini juga menunjukkan bahwa tidak ada interaksi antara verietas dan perlakuan beberapa dosis giberelin.
THE NEW DEVELOPMENT OF SUBJECT OF INTERNATIONAL LAW
Authors: Mansyur Supardan , Zunnuraeni Zunnuraeni
Published: May 2020

Nowdays the status of subject of international law is one of the most controversies in international law, particularly in part of corporation (multinational entities) and non governmental organizations. Since the status of subject of international law gives entities rights and duties under international law, it is important to find out the new development in the subject of international law. The issue in this article is what is the new development on the establishment and recognition of subject of international law?. To solve the issue, this article using normative reseach with conceptual approach and historical approach. The conclusion withdrown is that The new development in the subject of international law is the debate on the establishment and recognition of corporations and Non Governmental Organization as subject of international law. The view that corporation and NGO should established as subject of international law is based on the important role those entities has played in international plane. However, regardless the important role they play, they can not considered as the subject of international law since the lack recognition from international community.
Status of the Separated State Assets into BUMN Persero
Authors: Bafelanna Ghora Putra
Published: May 2020

The regulation of the status of state finances in the State owned enterprise (BUMN) environment in the BUMN Law and the Law on State Finance shows that there is a very significant difference in the status of state separated state assets from BUMN. The applied problem approach in this legal research is statutes approach. The Principle of State Assets Separation in the form of Equity Participation in Persero is also supported by the existence of a Fatwa from the Supreme Court Number WKMA / Yud / 20 / VIII / 2006 concerning the Separation of BUMN assets from state assets. The contents of the fatwa are related to Article 1 number 1 of the BUMN Law and Article 4 paragraph (1) of the BUMN Law which, according to the Supreme Court, is a more specific law concerning BUMN, it is clearly said that enterprises’ capital which originating from separated state’s earning and expenses shall be based on the principles of a sound corporate.
Criminal Law Politics: Corruption Eradication Strategy Through an Integrative Approach
Authors: Apriani Karlina Lina , Hidayat Ahmad Raji , Hendriyadi Rato Eko , Hamdani Wahyu , Surawijaya Surawijaya
Published: May 2020

The purpose of this research is to examine the politics of criminal law deeply in eradicating criminal law of corruption through an integrative approach. The method usingis normative legal research. Normative legal research methods or library research methods in legal research by reviewing existing legal materials. The integrative approach in overcoming corruption crime can be made integrally through two approaches, namely first, awareness between criminal politics and social politics directed to achieve particular objectives of the socio-political policies that have been set in order to achieve social welfare. Second, integration of efforts to tackle crime with penal and non-penal approach due to the reality of national law and the political facts of international law for enforcement on a national, regional, and global scale.
From Uncle Sam to Just Trump: A Long Way of Alternating Irony-hate-ambivalence among Russian Users-Students Regarding Politicians
Authors: Ulianovskii Andrei , Tatiana Dobrova , Filatova Olga , Golubev Vadim
Published: May 2020

The paper is discusses the role of emotionally significant political images in youth culture. The study covers the period between 2006 and 2017 during which Russia saw not only a political and economic transition but also dramatic changes in communication technology. The 6-stage research included two waves of testing in 2006, 2012, 2017. Respondents were aged 17 to 24 years old. In 2017 the general youth international value agenda can be considered formed, with its essential feature being the further reduction of the influence of advertising and communication of politicians’ brands.
Medical Tourism Market and Inter-Stakeholders’ Relations in Turkey: A Comparative Investigation From Reverse Innovation and Destination Governance Viewpoint
Authors: Aliu Dorian , Cilginoglu Hakki , Aliu Armando
Published: May 2020

This study aims to analyze inter-stakeholders’ interactions, destination governance, reverse innovation and the tasks of central government within the Turkish medical tourism market. The investigation’s objective is to shed light on scientists and practitioners regarding to what extent medical tourism is affected by stakeholders. Likewise, the originality of this investigation is that this study is the first attempt that links up reverse innovation and stakeholder approach as a holistic strategy and competitive advantage tool in medical tourism. The statistical evidences of Turkey also support the fact that the incline of medical tourism incomes and benefits is tightly bound on key inter-stakeholders’ collaborations, marketing tools, specific strategies, effective governance mechanism and cooperation with civil society organizations. This study is a thematic case that comprises particular research fields and formulates advanced arguments that are embedded in enriched relevant literature review and the highlights of the 7th International Health Tourism Congress.
Beyond Equity as Inclusion: A Framework of “Rightful Presence” for Guiding Justice-Oriented Studies in Teaching and Learning
Authors: Calabrese Barton Angela , Tan Edna
Published: May 2020

Current discourses of equity in teaching and learning are framed around calls for inclusion, grounded in the extension of a set of static rights for high-quality learning opportunities for all students. This essay presents a rightful presence framework to guide the study of teaching and learning in justice-oriented ways. This framework highlights the limitations of equity as inclusion, which does not adequately address the ways in which systemic injustices manifest in local classroom practice. Rightful presence orients the field towards the importance of political struggles to make present the lives of those made missing by schooling and discipline-specific norms. Three tenets for guiding the use of this framework in teaching and learning are offered. Two contrasting vignettes from STEM classrooms illustrate tenets and emergent tensions.
Promising pea varieties submitted for the State Variety Testing during 2017-2018
Authors: Aralova T. S. , Temchenko I. V.
Published: May 2020

The assessment of new pea varieties is carried out by the indicators of seed and feed productivity. The breeding value of new pea varieties vetch are established.
The agent for increasing soybean yield and for the Round-up resistant one decrease in the synthesis of unnatural peptides with glycine glyphosate
Authors: Kulyk M .F. , Kobak S. Y. , Khimich O. V. , Didorenko T. O. , Pohorila L. H. , Kulyk Y. M.
Published: May 2020

The purpose. In order to increase soybean yield to develop the agent for pre-sowing seed treatment and crop spraying in the budding phase, and application of an agent for Round-up resistant soybean should reduce the synthesis of unnatural peptides with glycine glyphosate in the structure of proteins, which can cause unpredictable consequences for animals and humans. Methods. Laboratory and field experiments on chickens and hens. Results. The agent «Zernovit» for pre-sowing seed treatment of soybean seeds (patent of Ukraine for utility model No.119739, 2017) and in the budding phase has been developed. In addition, the formation of unnatural peptides of glycine glyphosate in the structure of proteins decreases through the stimulation of protein synthesis in the genetically modified soybean when applying «Zernovit». Conclusions. The agent «Zernovit» for pre-sowing soybean seed treatment and application in the budding phase, which provides an increase by 16.8 % in yields against the control of 2.8 t/ha, has been developed and tested in the conditions of production, and when it is used in genetically modified soybean it reduces the synthesis of unnatural peptides with glycine glyphosate in the structure of soybean protein when sprayed with Round-up. This is due to the stimulation of the protein synthesis that prevents the inclusion of glycine glyphosate in the unnatural peptides of the protein synthesis.
Quality of winter wheat grain depending on the development of pathogenic mycoflora
Authors: Pohorila L. H. , Chornolata L. P. , Naidina T. V. , Lykhach S. M. , Zdor L. P. , Pyryn N. I. , Rudska N. O.
Published: May 2020

One of the main conditions for cultivating grain crops is the production of high yields of high quality grain. However, even well-formed healthy-looking seed are not always of good quality.

Wheat grain infestation with mycoflora occurs at different times, e.g. in the period of vegetation, during harvesting, especially in conditions of high humidity, during threshing, during storage of seeds with high humidity. Mycoflora on the seeds can be saprophytic (penicillas, mucor, alternaria, aspergillas, etc.) and pathogenic (helminthiosporium, fusariosis, septoriosis, etc.).

The purpose of our research was to study the level of winter wheat infestation with pathogenic microorganisms, to determine their species composition and to investigate whether the level of grain infestation affects protein and gluten content.

The species composition of the epiphytic mycoflora of winter wheat grain during the harvesting period and its influence on the food quality of grain are studied, measures are taken to limit its harmfulness.
The best families of Ukrainian black-and-white dairy breed in the conditions of leading breeding farms of Podillia
Authors: Zaets A. , Stoliar Z. , Mandrik M.
Published: May 2020

In the conditions of breeding farms PE «Radivske» and LLC «Zelena Dolyna» of the AF «Vyla» of Vinnytsia region, families of Ukrainian black-and-white dairy breed were studied. It is established that the families of Roses 127, Luski 1650 and Pava 911are the best one, and they belong to progressive ones by their stability of transfer of hereditary features. The families of Ivolga 1156, Ruta 1483, and Mazuli 2368 belong stably high-productive. When comparing families, Ivolga 1156, Pava 911 and Rosa 127 appeared to be best ones, and they had higher milk yields by 344 kg, 260 and 178 kg, respectively, compared with the average index for all families. As a result of the research, the genealogical homogeneity of families has been determined, which is 88.6—98.2 %, which indicates an increase and consolidation of high milk productivity in the next generations of the descendants.
Economic efficiency of growing corn hybrids for grain by different soil tillage technologies
Authors: Tomashuk O.
Published: May 2020

The article presents indicators of the economic efficiency of various technologies for growing corn hybrids for grain. The results of a 3-year field trial in maize of various maturity groups grown in the right-bank Forest-Steppe under different soil tillage models are highlighted. The costs of corn grain production under conventional cultivation and deep tillage, which averages 10,330 UAH per hectare of cropping area is studied. The rate of expenditures clearly correlated with the rate of hybrid productivity. High net profit of 20,119 UAH per hectare is shown when planting mid-ripening hybrid «Adevei» using intensification of the technological process. For other hybrids, conditionally net income fluctuated at the rate of 17,000 UAH per hectare. It is established that during the cultivation of corn for grain according to conventional technology and No-till, hybrids «Adevei» and «LG 3232» were characterized by the best indicators of economic efficiency.
Effect of seeding rate and row spacing on the height of Medicago sativa plants
Authors: Demydas H. I. , Kvytko M. H.
Published: May 2020

The purpose of the research was to identify the influence of cultivation technology elements on the parameters of Medicago sativa plant height of different geographical origin. Methods. Field, measurement, statistical methods. Research results. Observations showed that in the year of sowing during the vegetation of Medicago sativa its stalks were stunted and ranged within 28.0—33.3 cm irrespective of the seeding rate, varietal features and row spacing. In the second year of life in the budding phase, the plant growth rates of the varieties maintained throughout the growing season, whereas in the early flowering phase, they varied according to mowing and had a sinusoidal nature. The intensity of growth processes in the third year of life changed and in the budding phase of Medicago sativa it remained stable only in the first-second mowing ranging within 61.3—69.3 cm, whereas in the third-fourth mowing the indicators decreased from 59.1 up to 44.5 cm, or 10.2—16.8 cm. In the flowering phase, plant height was the highest in the first mowing and reached 99.7—101.4 cm, which decreased to 55.2 in the second and third mowing to 59.6 cm, or by 39.5—41.8 cm, regardless of the factors studied. Conclusions. The tendency towards the decrease in plant height with reduction of row spacing to 12.5 cm and increase of seeding rate and its growth at row spacing of 25 cm was revealed. The sinusoidal nature of Medicago sativa formation according to mowing both between the varieties and row spacing was established.