bluuebunny/crossref_metadata_2025 huggingface dataset:
PERANCANGAN DAN PENGEMBANGAN MODEL SILABUS, LESSON PLAN DAN MATERI PELATIHAN BAHASA INGGRIS BAGI MASYARAKAT DI DESA WISATA
Authors: Koerniawaty Francisca Titing
Published: December 2022

The President of Republic of Indonesia issued eight instruction at the Sidang Kabinet on January 4th 2016, one if wich was “Ensuring the Development of the 10 National Tourism Destinations or 10 New Bali, to meet the 2019 tourism target, the increasing of (devisa) from 120 billion into 240 billion. Bali as one of Indonesia’s prime tourism destination has also taken participation in increasing the (devisa). This can be seen from the support given by Bali government to establish the development program of ten tourism village in the program of the development of Bali in tourism for the next four years to develop the rural tourism. Based on this, the research was aimed at participating in the development of Human Resource in areas where tourism villages take place to allow the villagers to interact intensively with foreign tourists and give their best service. The participation was the design and development of English training with syllabus, lesson plan and training material as its results. The training put much emphasis on the increase of English communication ability based on the potential resource of Bedulu Village as one of tourism village. The method of the research was Design and Development, porposed by Ellis and Levy (2010), that consist of several phases in designing and developing English training. We hope that the output of the study will results in the realization of society service at tourism village as English training.
KAJIAN PRODUK WISATA BAHARI PANTAI TANJUNG BENOA
Authors: Arya Astina Made , Muliadiasa Ketut
Published: December 2022

This study aims to identify the quality of marine tourism products which are limited to indicators of Attractions, Accessibility, Amenities, and Ancilary on Tanjung Benoa marine tourism destinations, knowing the socio-demographic conditions of tourists who come to Tanjung Benoa marine tourism destinations, as well as contributing marine tourism development strategies in Tanjung Benoa. Based on the purpose of this study, several theories, concepts and literature studies referred to this study include the concept of tourism, marine tourism, product quality (tourist attraction), product development. Meanwhile, the research method that used in this study was descriptive analysis about the conditions of Attractions, Accessibility, Amenities, and Ancilary in marine tourism on the Tanjung Benoa beach. Direct observation and distribution of questionnaire for the tourists in the Tanjung Benoa area was carried out to directly assess the object of research at this location. The analysis of secondary data consist of the number and condition of facilities and infrastructure assessed from the perception of tourists. As the result of the problem formulation in this study, it could be obtained the data or information about the condition of attraction quality, amenities and activities in Tanjung Tanjung Benoa marine tourism, and contributes to the development strategy of the tourism area. The results of this study could be used to develop marine tourism in the Tanjung Benoa tourist area which is expected to be a quality and sustainable marine tourism area. Keywords: Marine Tourism, Quality of tourist attraction, Development potential
MOTIVASI TENAGA KERJA BALI BEKERJA DI KAPAL PESIAR DISNEY CRUISE LINE
Authors: Astuti Pranadewi Putu Mira
Published: December 2022

The objective of this study are to encounter the level of Balinese labor motivation for working in Disney Cruise Line, determine the difference motivation for them who have not worked at the other cruise line company and who have experienced at cruise line before to work in Disney Cruise Line and also investigate the factors which motivate Balinese Labors for working in Disney Cruise Line. The factors in this study are working condition, compensation, company policy, change to have promotion and acknowledgement. In this research, there were 150 respondents selected as a sample using purposive sampling method. The instrument used is questionnaire data analyzed by confirmatory factor analysis and determinant analysis with SPSS program version 20.0. The findings of this research are the level of Balinese labor motivation to work in Disney Cruise Line  generally in average level, there are differences motivation between Balinese labor who have not worked at the other cruise line company and who have experienced at cruise line before to work in Disney Cruise Line in which the motivation level of inexperienced Balinese labors is higher than experienced ones, and the five factors in this study have their own influence to labors motivation, but the most strong factor is working condition factor and the weakest one is opportunity to have promotion.  Key Words: Working Motivation, Balinese Labors Cruise Ship
STRATEGI PENGEMBANGAN TENUN RANGRANG SEBAGAI PRODUK WISATA ANDALAN NUSA PENIDA BALI
Authors: Amir Firlie Lanovia , Riko Hendrajana I Gusti Made
Published: December 2022

This study was made to study the potential of Tenun Rangrang of Nusa Penida, as well as to determine strategies and programs that can be done to develop the potential of Tenun Rangrang as tourism product. This study uses a qualitative descriptive approach to measure related variables, and uses SWOT matrix to explain and determine data in the formulation of strategies and programs. From the results of data processing, there are several decisive factors in the development of the potential of Tenun Rangrang, which are incorporated in internal and external factors. Of the two factors has successfully formulated 4 strategies and programs to develop them, including the SO strategy (developing the appeal of Tenun Rangrang including the surrounding environment), ST (Developing cultural tourism in Nusa Penida), WO (doing the right promotion), and WT (related to human resource development). It is hoped that this research can also be a reference for several policies that can be taken by the local government to develop tourism in Nusa Penida, as well as for people to be able to develop the potential of Tenun Rangrang to be much better. Keywords: Potential, Tenun Rangrang, Sustainable Tourism
STRATEGI PENGEMBANGAN ESPACE SPA BALI DALAM MENGHADAPI PERSAINGAN GLOBAL
Authors: Dwi Poetranto Isa Wahjoedi , Zuraida Lukia
Published: December 2022

This research aim to find out the development strategies of  Espace Spa Bali in facing global competition, to find out the the guests characteristic and to find out of the guest push and pull motivation in visiting Espace Spa Bali. Random sampling was used with total sample of 45 guests (15% of 300 visiting guests in a month). The data were taken from interview and questionnaire. The SWOT analysis technique was used to analyze the data obtained through the interview, and the descriptive frequency technique was used to analyze the guests characteristics and motivation questionnare data. The result of research showing that Espace Spa Bali is on quadran I (aggressive) with x axis (2.50) and y axix (2.45). the developed strategies are strengthening the brand, quality, marketing and price, also increasing the cooperation with stakeholders. The guest mostly female coming from Australia, France and Japan with the education background from senior high school, diploma, bachelor degrees, ages range from 26 till 56 years old, married status and single are balanced. Guests mostly has job as a staff or office employees and first time visiting Bali. The push motivation factor are indicate that the reason guests visiting Espace Spa Bali for rejuvenation, social an joy, luxury life style,  health and beauty, relaxation, escape from routin job. The pull motivation factor are indicate that the guests choose Espace Spa Bali because of proffesionalism and attitude  of therapist, good amenities, clean and tidy facility, the room decoration adjust for  comfortable treatment Keywords: Global Competition, Development Strategies, Characterics, Push Motivation, Pull Motivation
FENOMENA SAMPAH DAN PARIWISATA BALI
Authors: Sutrisnawati Ni Ketut , M.Purwahita A.A.A Ribeka
Published: December 2022

Garbage is an inseparable part of human life. Garbage is produced by humans as waste in fulfilling their needs. However, the presence of the garbage cause major environmental problems and threat to the tourism sector in Bali. Tourist comes to Bali to enjoy the splendour of its nature and cultures, but they have to see the reality that the island is less than their expectations. In contrast to Bali's image as a sun-drenched tropical island and the last paradise on earth, the ugly truth is that the island is awash in garbage. The beaches littered with plastic bags, bottles, straw, plastic wrappers. This phenomenon is getting worst especially on rainy season where most of garbage which is washed into waterways by the daily rains and carried into the sea resulting big mount of waste in the coast area.  Complaints came from tourists about this issue is an indication that they feel uncomfortable with the presence of this garbage. If there is no serious action and commitment to solve this issue, slowly but surely there are more tourist will skipping to visit Bali. Regarding to this issue, Balinese have no one to blame but themselves. Garbage becomes a big problem because people have a thought that illegal dumping is the norm. The active participation of all stakeholders such as goverment, industry, local community also visitor is needed to overcome this problem to realize sustainability of environment and tourism of Bali.  Keywords: Garbage, Tourism, Sustainable Tourism
DAMPAK BENCANA ALAM BAGI SEKTOR PARIWISATA DI BALI
Authors: Sutrisnawati Ni Ketut
Published: December 2022

Natural disasters are natural phenomenon that can occur at any time anywhere. Natural disasters negatively affects society, either through damage to property or through loss of life, environmental damage, also affect various aspects of human life, such as economic, socio-cultural, security, etc. Tourism is an industry continues to be developed in many countries in the world. Tourism as a smokeless industry is strongly influenced by various aspects, one of which is security. Disaster as part of security has a huge influence on the tourism sector. Humans feel anxious and worried about visiting destinations that are prone to disasters. It cannot be denied that Bali is highly dependent on the tourism sector. The Mount Agung eruption in 2017, which lasted until 2018, had an impact on most Balinese people, especially those working in the tourism sector. Reduced tourist arrival due to travel warnings, as well as the closure of Ngurah Rai airport for several days due to volcanic ash bursts had caused the industry in the tourism sector to experience a downturn. To reduce the impact of natural disasters, especially on the tourism sector, various efforts and cooperation from all stakeholders are needed to jointly find solutions to solve the problems arising from this disaster. This solution can be in the form of prevention / pre-disaster, preparedness and post-disaster /recovery. With the existence of concrete efforts and actions before, during and after a disaster, it is expected to create a positive image of Bali so as to create sustainable tourism without worrying for natural disasters. Keywords: Natural Disasters, Tourism Sector, Bali
THE STRUGGLING OF WOMEN MASSAGERS IN NUSA DUA TOURISM AREA
Authors: Santi Diwyarthi Ni Desak Made
Published: December 2022

This research analyze women workers in informal sector, as massager in Nusa Dua tourism area. The research questions are the Strengths, Weaknesses, Opportunities and Threats faced by women workers in informal sector in Nusa Dua tourism area. This research is Quantitative Research by using  SWOT Analysis Technique. The results shows Internal and External Factors from women worker in informal sector. The Internal factors are Strength and Weakness, and External factors are Opportunity and Threat. Internal Factors are Strength: Balinese women are known to be friendly and courteous, Female massagers on the beaches of Nusa Dua tourism area are competent human resources in the field of tourism because of experienced and well trained.  Weakness: Trip to Nusa Dua that sometimes takes a long time because of traffic jam, Great influenced by weather change factors, Boredom and no career development opportunities for women massagers. External Factors are  Opportunity: Opportunities to participate actively in tourism, Improve the experience in tourism, Opportunity to interact with various cultural aspects from outside in open knowledge insight.  Threath: Increasing number of other tourist destinations that make more and more destination for tourists, The offer of an existing Social Culture attraction keeps visiting tourists who can feel bored and no longer interested in the offer. Keywords: Struggling, Women, Massagers, Tourism
Telehealth in the context of COVID-19: An Analysis of Men’s Usage and Perceptions in Comparison to In-Person Healthcare
Authors: Ziesing Samuel J. , Antwerpen Natasha van , Turnbull Deborah , Martin Sean A. , Gill Tiffany K. , Opozda Melissa J.
Published: December 2022

Introduction:

The rise in telehealth adoption due to the emergence of COVID-19 may have had implications for men who experience barriers to accessing traditional forms of healthcare. This study sought to explore how a sample of older men interacted with telehealth during the pandemic.

Method:

Data sourced from a cross-sectional, population-based questionnaire (completed from October 2020 to March 2021) were used to analyze the characteristics of older men’s (a) use of telehealth services, and (b) perceptions of telehealth in comparison to in-person healthcare using Andersen’s Behavioral Model of Health Services Use.

Results:

Of the 731 participants (mean age = 69 years; SD = 9.6), 241 (32.9%) had used telehealth services during pandemic restrictions. Most of them who had used telehealth (63.1%; 152/241) thought it was “just as good” as in-person, 4.1% (10/241) believed it was “better,” and 25.7% (62/241) thought it was “worse.” Men with more chronic conditions were more likely to (a) have used telehealth (odds ratio [OR], 1.44 [95% CI, 1.21–1.71]) and (b) perceived telehealth as “better” or “just as good” as in-person healthcare (OR, 1.63 [95% CI, 1.17–2.29]). Men with clinically significant depressive symptoms were more likely to view telehealth as worse than in-person care (OR, 0.32 [95% CI, 0.12–0.88]).

Conclusion:

While telehealth is acceptable to the majority of middle-aged and older men who have used it during the pandemic, attitudes may vary according to their current health issues. Men with more chronic conditions are more likely to feel positive about telehealth, while those with clinically significant depression symptoms are more likely to view it negatively. Healthcare providers should consider men’s needs and preferences when offering telehealth services.
“No One Thinks of Greenland:” US-Greenland Relations and Perceptions of Greenland in the US from the Early Modern Period to the 20th Century
Authors: Heidbrink Ingo
Published: December 2022

The history of US-Greenland relations and the perception of Greenland in the US is a near complete historical desideratum with only few works dealing with the subject at all and those publications covering mainly the few well-known historic events. Neither US nor Danish or Greenlandic historians have dealt with the perception of Greenland in the US from Early Modern to today in its entirety.

The article provides an overview of the history of perception of Greenland in the US and the bilateral relations of these countries from Early Modern to today, but more important also asks the question why this subject has been largely ignored. 

The title of John Griesemer’s novel “No one thinks about Greenland” is used as a parable to describe these reasons and the attitude of the US and US foreign policy towards Greenland. Furthermore, it is analyzed, why the US tried purchasing Greenland several times and why certain groups in the US had an interest to keep the US-Greenland relations in the shadows. It is also described how not purchasing Greenland made perfect sense for the US and generated a political vacuum on the island, that provided some unique opportunities for the US military. Throughout history it remained true that nearly nobody in the US thought about Greenland, resulting in a unique history of bi-lateral relations.
China and the 21st Century Arctic: Opportunities and Limitations
Authors: Lavengood Zachary
Published: December 2022

In 2018 The People’s Republic of China (PRC) released its Arctic policy and articulated its position, principles, and goals as a “near-Arctic state.”  In the years since, China has become a central focus of the growing academic and professional discourse surrounding the emerging Arctic and has positioned itself as a consequential actor in regional affairs. This article examines the opportunities and limitations for China in the High North by focusing on its four key drivers for Arctic engagement: resource extraction, international shipping, scientific pursuits, and international prestige. This article finds that while China’s involvement in Arctic affairs is growing, there are still significant roadblocks to its ambitions which it will need to overcome in order to reach its goal of being recognized as an Arctic power.
RELIGIOUS TOLERANCE LIMITS: A SEMIOTIC LINGUISTIC ANALYSIS OF AL-KĀFIRŪN CHAPTER
Authors: Supardi Supardi
Published: December 2022

This article aims to find the demarcation limit lines of religious tolerance from al-Kāfirūn chapter of the Holy Qur’an and respond to some issues developing in Indonesian. This study is based on an exploratory analysis of semiotic linguistic meanings of the chapter with an intention to respond to Indonesian Issues regarding the practices of religious greeting of the opening public speech, congratulating other religious celebrations, and singing performance of muslim students’ in a church as cases in point. This study found that the religious tolerance limits are ‘the belief’ and ‘the rituals’. Three activities are considered to go beyond the religious tolerance limits drawn from the chapter being studied, namely: (1) compromising religious belief, (2) mixing religious ritual activities, and (3) imposing religion on others. These three are, among others, the measurement of the activities considered tolerance or intolerance.
Recurrent infection and embolism following tricuspid valve repair for infective endocarditis in an intravenous drug user: A clinical dilemma
Authors: Ahmed Yasir , Poon Shi Sum , Aslam Umair , Kumar Pankaj
Published: December 2022

Management of infective endocarditis (IE) in intravenous drug users
(IVDUs) can be challenging due to risk of reinfection following surgery.
Although complex repair techniques that can be utilized to reconstruct
the tricuspid valve after extensive debridement, treatment of active
IVDU is incomplete without effective post-operative harm reduction
intervention program.
The Procedure of Detecting Drought Trend by Using Şen’s Innovative Trend Analysis Methodology
Authors: AYDIN Mahsum
Published: December 2022

Drought is one of the most important phenomena for humans and living
things. Especially in recent years, the effect of drought has reached
levels that cannot be ignored. This situation causes negative effects on
water resources. In order to minimize these negative effects, it is of
great importance to know the trend of drought over time. Many methods
are used in the literature to determine the severity of drought. The
most widely used of these methods is the Standard Precipitation Index
(SPI), which calculates based on precipitation data. There are different
classifications for drought severity in the SPI method. Therefore, it is
of great importance to know the individual trends for each
classification. Classical trend-detecting methods (such as Mann-Kendall)
require a separate analysis for each drought classification. However,
with Şen’s Innovative Trend Analysis (ITA) method, it becomes possible
to determine the trends for all drought classifications on a single
graphic. In this way, the change of drought events over time can be
easily determined for all drought classifications.
The accuracy of two algorithms of artificial intelligence based on neural networks and the CaRDIA-X algorithm in the identification of electronic implantable cardiac devices by chest x-rays.
Authors: Córdoba Laura Fernanda Gilón , Rodríguez Juan Felipe Betancourt , García Angel , Cáceres Edward Andrés , Moreno-Mercado Sebastián , Buitrago Diego Armando Ospina , Gómez Sara , Olejua Peter
Published: December 2022

Objectives: In this study, we aim to describe the diagnostic
accuracy of two applications neural networks-based system and a visual
algorithm performed by different evaluators to identify the manufacturer
of electronic implantable cardiac devices by chest x-rays.
Background: cardiac rhythm devices frequently require
interrogation, and they have different software depending on the
manufacturer. Currently, there are a visual algorithm and two
applications based on artificial intelligence for the identification of
the manufacturer from chest radiographs. Methods: Retrospective
trial between January 2010 and December 2021 at a single institution.
Chest radiographs were obtained from patients with cardiac devices; they
were cropped and resized to 224 by 224 pixels. Then, they were analyzed
using the applications Pacemaker ID with a cell
phone, Pacemaker ID web and PPMnn
web, and the visual algorithm CaRDIA-X
performed by evaluators at different levels of
training. Results: 400 radiographic images with cardiac devices
were collected comprising 4 manufacturers and 40 different models. The
agreement for Pacemaker ID with a cell phone was
90.6% ( p <0.001), for Pacemaker ID
web was 81.2% ( p < 0.001); and
for PPMnn web was 82% ( p <
0.001). The agreement from the CaRDIA-X algorithm
performed by 4 evaluators ranged from 73.8% to 97.7% ( p
< 0.001). Conclusions: The use of applications based
on neural networks offers a good agreement in the identification of the
manufacturer and is a tool for clinical use. In our paper, the visual
algorithm has a better agreement in identifying the manufacturer and it
doesn’t require much training.
ROLE OF FACTS DEVICES IN POWER SYSTEM WITH OPTIMIZATION TECHNIQUES
Authors: K RAVI , CHETHAN M
Published: December 2022

In electrical power systems, FACTS devices effectively control power
flow and change bus voltages, leading to lower system losses and
excellent system stability. The article discusses the research from the
last decade that evaluated various methods for placing FACTS devices
using the meta-heuristic approach to address the positioning of Facts
devices to maintain proper bus voltages and control line flow and
improve the overall system efficiency. Several models and techniques
suggest that devices can be placed in a particular location with
different parameter settings. Finally, the optimization problem improved
system performance by decreasing power loss, improving the voltage
profile and power angle at each bus, raising the L-index, and minimizing
generating costs. FACTS devices can increase the transmission line’s
capacity for transferring power by increasing the voltage at its
terminals at both ends and reducing line reactance. The FACTS controller
must be installed in the distribution and transmission lines to maximize
the power flow. Various techniques are used for the best placement of
FACTS controllers, including analytical methods, arithmetic programming
approaches, meta-heuristic optimization approaches, and hybrid
approaches—this paper analyses numerous analytical and meta-heuristic
optimization techniques to place FACTS controllers in the most
advantageous locations. The fundamental problems in intelligent power
systems, such as improving stability, power quality, and managing
congestion, are discussed in this study, along with several applications
of FACTS devices. The cutting-edge power systems of today provide users
with constant, high-quality power through smart grids and smart meters.
The motivation for the review
Graph-Based Root Cause Localization in Microservice Systems with Protection Mechanisms
Authors: Zhang Haitao , Tian Wei , Yang Neng , Zhang Yepeng
Published: December 2022

Nowadays, the protection mechanisms are introduced into microservice
systems to ensure the stable operation of services. However, existing
approaches ignore the impact of protection mechanisms on the root cause
localization of abnormal services. Specifically, the circuit breaking
and rate limiting mechanisms can refuse service requests and thus change
the way of anomaly propagation. Moreover, different service request
frequencies and response time make service dependencies change
dynamically, resulting in different probabilities of anomaly propagation
among services. In this paper, we propose a novel framework named
MicroGBPM to locate the root cause of abnormal services, which considers
the impact of the protection mechanisms. We model anomaly propagation
among services as a dynamically constructed service attributed graph
with metrics and traces when a failure occurs. To eliminate the impact
of the protection mechanisms, we design a two-stage dynamic calibration
strategy to adjust the probability of anomaly propagation among
services. Then we propose a random walking approach to calculate the
root cause results by using the PageRank algorithm. The experimental
results show that MicroGBPM improves the accuracy of root cause
localization compared to other approaches in microservice systems with
protection mechanisms.
Signal detection in pharmacovigilance without a priori hypothesis: a systematic review of the literature
Authors: Gaucher Louis , Sabatier Pierre , Katsahian Sandrine , Jannot Anne-Sophie
Published: December 2022

Introduction: The emergence of real-life health databases has
opened the door to studies for signal detection in pharmacovigilance
without the formulation of an a priori hypothesis, i.e., without
defining a drug/adverse drug event (ADR) pair. Our objective was to
perform a systematic review of this type of study and the statistical
methods used in this context. Methods: Studies about drug
signal detection without a priori hypotheses published in the
MEDLINE database between 2012 and 2021 were included. Database name and
type, statistical methods, ATC class for the studied drug(s) and SOC
MedDRA classification for the studied ADR were extracted.
Results: Ninety-two studies were included. Pharmacovigilance
databases were the most used type of database. Most studies performed a
disproportionality analysis using frequentist or Bayesian methods. The
most studied drug classes were anti-infectives, nervous system drugs,
and antineoplastics and immunomodulators. No common procedure was
implemented to correct for multiple testing. Conclusions: There
are very few statistical methods used for drug signal detection without
a priori hypotheses, with no consensus-based method and no interest in
multiple testing correction. This review argues for the establishment of
guidelines to perform such studies.
Primary hyperparathyroidism in horses: What can we learn from human medicine?
Authors: Johnson Philip , Townsend Kile
Published: December 2022

Equine primary hyperparathyroidism is rare compared with the condition
in human medicine where it is often encountered and represents the most
common explanation for hypercalcemia in the outpatient setting. Primary
hyperparathyroidism results from a hyperfunctioning parathyroid gland
and surgical treatment (parathyroidectomy) is typically curative.
Successful surgical removal of a diseased parathyroid gland can be
challenging in horses as both normal and hyperfunctioning glands are
difficult to localize. Identification of surgical targets using
ultrasonography and/or Technetium-99m sestimibi scintigraphy are useful
for this purpose in both the human and equine contexts. However, these
localization approaches are not aways effective. Moreover, not all
patients are candidates for general anesthesia and surgery and the costs
associated with diagnostic localization and parathyroidectomy may be
prohibitive for some owners. This commentary presents information about
primary hyperparathyroidism in the event that it is not treated and
strives to review aspects of the disease when left untreated from the
human medical context.
Klotho alleviates vancomycin-induced acute kidney injury by upregulating anti-oxidative capacity via JAK2/STAT3/GPx3 axis
Authors: Wang Meng Meng , Zhou Yue , Yin Rui , Zheng Yi , Zhao Wei
Published: December 2022

Background and Purpose: Emerging studies indicated that Klotho is a
marker of renal injury and owns a protective effect on different kinds
of kidney diseases. However, the role of Klotho in vancomycin
(Van)-induced acute kidney injury (AKI) is largely unclear. Hence this
study aimed to explore the regulatory mechanism of Klotho in Van-AKI.
Experimental Approach: The mRNA expression of Klotho and the
JAK2/STAT3/GPx3 axis was assessed by RNA sequence analysis after the Van
challenging; the mechanism action of Klotho was examined in vitro by
Klotho small interfering RNA and recombinant Klotho. The expression of
reactive oxygen species and antioxidant enzymes was detected by flow
cytometry and spectrophotometry. Transmission electron microscopy was
performed to scan the structural damage of mitochondria. Western blot,
qPCR, and immunofluorescence were applied to further explore the
function of the JAK2/STAT3/GPx3 axis in Van-AKI. Key Results: RNA
sequence analysis indicated that Van challenging reduced the expression
of Klotho and GPx3, but increased JAK2/STAT3. In vitro, Klotho siRNA
enhanced the production of reactive oxygen species and the cell
apoptosis ratio by regulating the JAK2/STAT3/GPx3 axis, while the
decrease of GPx3 was prevented by specific inhibitors of JAK2/STAT3. In
contrast, recombinant human Klotho showed the opposite function to
Klotho siRNA. In vivo, recombinant mouse Klotho improved the
anti-oxidative enzyme level and mitochondria damage as well as renal
dysfunction and histological damage via upregulating anti-oxidative
ability. Conclusion and Implications: To conclude, the study evidenced
that recombinant Klotho ameliorated Van-induced AKI via the
JAK2/STAT3/GPx3 signaling axis by upregulating anti-oxidative ability.
A novel efficient method of estimating suspended total sediment load fraction in natural rivers
Authors: Noh Hyoseob , Park Yong Sung , Seo Il Won
Published: December 2022

Sediment transport load monitoring is important in civil and
environmental engineering fields. Monitoring the total load is
difficult, especially because of the cost of the bed load transport
measurement. This study proposes estimation models for the suspended
load to total load ratio (Fsus) using dimensionless hydro-morphological
variables. Two prominent variable combinations were identified using the
recursive feature elimination procedure of support vector regression
(SVR): (1) W/h, d*, Reh, Frd, and Rew and (2) Reh, Fr, and Frd. The
explicit interactions between Fsus and the two combinations were
revealed by two modern symbolic regression methods: multi-gene genetic
programming and Operon. The five-variable SVR model showed the best
performance (R2=0.7722). The target dataset was clustered by applying a
self-organizing map and Gaussian mixture model. Through these steps, Reh
and Frd are determined as the two most influential variables.
Subsequently, the one-at-a-time sensitivity of the input variables of
the empirical models was investigated. By referring to the clustering
and sensitivity analyses, this study provides physical insights into
Fsus controlling relationships. For example, Fsus is proportional to Reh
and is inversely related to Frd. The empirical models developed in this
study are applicable in practice and easy to implement in other
real-time surrogate suspended-sediment monitoring methods, because they
only require basic measurable hydro-morphological variables, such as
velocity, depth, width, and mean bed material grain size.
Understanding advances and challenges of urban water security and sustainability in China based on water footprint dynamics
Authors: Gong Binghua , Liu Zhifeng , Liu Yupeng , Zhou Shunli
Published: December 2022

Sustainability of China’s numerous cities are threatened by both
quantity- and quality-induced water scarcity, which can be measured by
the water footprint from a consumption (WFcons) or production (WFprod)
perspective. Although WFcons was widely assessed, the changes in WFprod
of China’s cities were still unclear. Taking 31 major cities as
examples, this study revealed the dynamics of urban WFprod in China from
2011 to 2016. First, the spatiotemporal patterns of WFprod and water
deficit were evaluated and then the main reasons for the WFprod dynamics
and its implications for urban sustainability were explored. A
large-scale decrease in urban WFprod in China was found, with the
average WFprod decreasing from 13.8 billion m³ to 10.3 billion m³ and
the per capita WFprod decreasing from 1614.8 m³/person to 1184.0
m³/person (i.e., falling by more than a quarter in just six years). Such
shrinkage was particularly evident in drylands, eliminating the water
deficit in Xi’an and Xining. The reduction in grey WFprod caused by
implementing water pollution prevention policies and other relevant
measures played the most important role in the savings. In the future,
the implementation of updated pollution discharge standards is projected
to allow more cities to escape water deficits; however, the rapid growth
of the domestic and ecological blue WFprod caused by urbanization and
urban greening would destabilize this prospect. Thus, attention should
be given to both water pollution prevention and domestic and ecological
blue WFprod restriction to further alleviate urban water scarcity in
China.
Tropical Cyclone Forecasts in the DIMOSIC Project -- Medium-Range Forecast Models with Common Initial Conditions
Authors: Chen Jan-Huey , Zhou Linjiong , Magnusson Linus , McTaggart-Cowan Ron , Köhler Martin
Published: December 2022

The Tropical cyclone (TC) forecast skill of the eight global
medium-range forecast models which are participating in the DIMOSIC
(DIfferent Models, Same Initial Conditions) project is investigated in
this study. Each model was used to generate 10-day forecasts from the
same initial conditions provided by the European Centre for Medium-Range
Weather Forecasts. There are a total of 123 initial dates spanning in
one year from June 2018 to June 2019 with a 3-day interval. The TC track
and intensity forecasts are evaluated against the best track dataset.
TC-related precipitation and tropical cyclogenesis forecasts are also
compared to explore the differences and similarities of TC forecasts
across the models. This comparison of TC forecasts allows model
developers in different centers to benchmark their model against other
models, with the impact of the initial condition quality removed. The
verifications reveal that most models show slow-moving and
right-of-track biases in their TC track forecasts. Also, a common dry
bias in TC-related precipitation indicates a general deficiency in TC
intensity and convection in the models which should be related to
insufficient model resolution. These findings provide important
references for future model developments.
Prediction of Plasma Pressure in the Outer Part of the Inner Magnetosphere using Machine Learning
Authors: Li Songyan , Kronberg Elena A. , Mouikis Christopher G. , Luo Hao , Ge Yasong S , Du Aimin
Published: December 2022

The information on plasma pressures in the outer part of the inner
magnetosphere is important forsimulations of the inner magnetosphere and the better understanding of
its dynamics. Based on 17-yearobservations from both CIS and RAPID instruments onboard the Cluster
mission, we used machine-learning-based models to predict proton plasma pressures at energies
from ~40eV to 4MeV in the outerpart of the inner magnetosphere (L*=5-9). The location in the
magnetosphere, and parameters of solar,solar wind, and geomagnetic activity from the OMNI database are used as
predictors. We trained severaldifferent machine-learning-based models and compared their performances
with observations. Theresults demonstrate that the Extra-Trees Regressor has the best
predicting performance. The Spearmancorrelation between the observations and predictions by the model data
is about 68%. The mostimportant parameter for predicting proton pressures in our model is the
L* value, which is related to thelocation. The most important predictor of solar and geomagnetic activity
is the solar wind dynamic pressure. Based on the observations and
predictions by our model, we find that no matter under quiet or
disturbed geomagnetic conditions, both the dusk-dawn asymmetry at the
dayside with higher pressures at the duskside and the day-night
asymmetry with higher pressures at the nightside occur. Our results have
direct practical applications, for instance, inputs for simulations of
the inner magnetosphere or the reconstruction of the 3-D magnetospheric
electric current system based on the magnetostatic equilibrium, and can
also provide valuable guidance to the space weather forecast.
Influence of water hyacinth (Eichhornia crassipes) on concentration and distribution of Escherichia coli in water surrounding an informal floating community in Iquitos, Peru
Authors: Neumann Rebecca B , Fernández Susan Cilene Paredes , Andrews Leann , Alarcón Jorge A , Group InterACTION Labs InterACTION Labs Working
Published: December 2022

Floating communities exist throughout the world. Many live on water with
a high pathogen load due to difficulties associated with sewage
management. In Claverito, an informal floating community in Iquitos,
Peru, we conducted a controlled experiment to test the ability of water
hyacinth (Eichhornia crassipes) to remove Escherichia coli from water.
When river E. coli concentrations were at or below ~1500
CFU 100 mL-1, water hyacinth reduced shallow concentrations (8-cm depth)
down to levels deemed safe by U.S. EPA for recreational use. Above this
threshold, plants were able to reduce E. coli levels within shallow
water, but not down to “safe” levels. At deeper depths
(>25 cm), there was evidence that plants increased E. coli
concentrations. Water hyacinth removed E. coli from shallow water by
providing a surface (i.e., submerged roots) onto which pathogens sorbed
and by protecting organisms that consume E. coli. Unfortunately, because
of root association, the total E. coli load within the water column was
greater with water hyacinth present, and results hinted that the plants’
protective environment also harbored parasites. The use of water
hyacinth to keep surface water around floating communities low in E.
coli could be beneficial as this is the water layer with which people
most likely interact. Aquatic vegetation naturally proliferates in and
around Claverito. While this study was based on curating aquatic plants
in order to achieve a water-quality outcome, it nonetheless supports
concrete actions for Claverito residents under non-curated conditions,
which are outlined at the end of the manuscript.
Agrarian relations on the island of Mljet in the 19th century
Authors: Gjurašić Marija
Published: December 2022

The paper analyses land property relations on the island of Mljet in the 19th century based on the information from different sources, especially from cadastre, land registry documentation and inherited estates. In order to understand them, the paper shows in detail the situation in other parts of Dalmatia at the time, but also their genesis on the island beginning from the 14th century. A special attention is paid to understanding the differences related to land property relations on the eastern and western part of Mljet in the 19th century.
The Impact of COVID-19 Mobility Restrictions on Trade Facilitation at Borders in the Central Asia Regional Economic Cooperation Region
Authors: Kim Kijin , Abesamis Jerome , Ardaniel Zemma
Published: December 2022

This paper investigates the impact of COVID-19 mobility restrictions on the time taken for cargo to clear borders in the Central Asia Regional Economic Cooperation (CAREC) area. The findings suggest that cargo processing time could increase by up to 70% when the most stringent level of mobility restrictions was imposed. The results also suggest that outbound border-crossing points were more affected by measures than inbound points, but were more resilient in that impact was short-lived. The study found that both inbound and outbound times increased when mobility restrictions in a trading partner tightened.
Solution for TSP/mTSP with an improved parallel clustering and elitist ACO
Authors: Baydogmus Gozde
Published: December 2022

Many problems that were considered complex and unsolvable have started to solve and new technologies have emerged through to the development of GPU technology. Solutions have established for NP-Complete and NP-Hard problems with the acceleration of studies in the field of artificial intelligence, which are very interesting for both mathematicians and computer scientists. The most striking one among such problems is the Traveling Salesman Problem in recent years. This problem has solved by artificial intelligence?s metaheuristic algorithms such as Genetic algorithm and Ant Colony optimization. However, researchers are always looking for a better solution. In this study, it is aimed to design a low-cost and optimized algorithm for Traveling Salesman Problem by using GPU parallelization, Machine Learning, and Artificial Intelligence approaches. In this manner, the proposed algorithm consists of three stages; Cluster the points in the given dataset with K-means clustering, find the shortest path with Ant Colony in each of the clusters, and connect each cluster at the closest point to the other. These three stages were carried out by parallel programming. The most obvious difference of the study from those found in the literature is that it performs all calculations on the GPU by using Elitist Ant Colony Optimization. For the experimental results, examinations were carried out on a wide variety of datasets in TSPLIB and it was seen that the proposed parallel KMeans-Elitist Ant Colony approach increased the performance by 30% compared to its counterparts.
CO2 Capture Performance of Graphene Oxide Synthesized Under Ultrasound Irradiation
Authors: Sezgin Deniz , Sarı Yılmaz Müge
Published: December 2022

Nowadays, CO2 capture is a vital technology to notably reduce the uncontrolled released CO2 emissions. CO2 capture using graphene oxide, a derivative of graphene, has become of tremendous interest due to its unique morphology. In this present work, graphene oxide (GrO) was synthesized under ultrasound irradiation according to the modified Hummers’ method and its CO2 capture performance was examined. The X-ray powder diffraction (XRD) and Fourier transform infrared (FTIR) analyses were applied to explore the structure of the sample. CO2 capture performance of GrO was examined by performing TG analysis under different temperatures. The CO2 adsorption capacity of GrO was reached up to 1.04 mmol g-1 at 25°C. The experimental data getting from the kinetic study revealed that the Avrami model better described the CO2 adsorption.
Przemiany osadnicze na terenie Wrocławia i jego przedpola we wczesnym średniowieczu
Authors: Pankiewicz Aleksandra , Rodak Sylwia
Published: December 2022

Within the research of the most important early medieval centers in Polish territory, the study of the strongholds themselves and of their background is centrally important. In the case of Wrocław, such analyses have been undertaken several times, but in view of the enormous increase in the sources obtained in the course of wide-ranging rescue research, it worth taking a look at this problem again. The aim of this article is to capture the dynamics of settlement changes in the early Middle Ages in the area of today’s city of Wroclaw and its closest surroundings. In order for this study to be credible, all possible data was used (AZP – Archaeological Photo of Poland, available publications, materials collected in museums, unpublished reports from research) in order to recreate the image of the settlement of this period. The result is a new look at the development of settlement in the vicinity of a large center, like Wroclaw, and an attempt to capture the factors determining these transformations.
Ośrodki węzłowe i kontakty transbałtyckie pomiędzy społecznościami północno-zachodniej Rusi i ziem polskich w X stuleciu
Authors: Musin Aleksandr , Stanisławski Błażej
Published: December 2022

The inflow of oriental silver to the lands of Western Slavdom, through the centers of Eastern Europe via the Baltic Sea, was the main determinant of material contacts between the communities of the two regions of the continent. However, they show only one direction – namely, from east to west. The results of the latest research show their second aspect, this time relations from west to east. To the centers located in the north-western zone of Eastern Europe arrived ceramic vessels specific to pottery of the North-Western Slavic territory or people who made them there on the spot. In addition, Tornow type vessels have been registered in Gorodok on the Lovat river. The chronological framework of the occurrence of these artefacts corresponds to the times when the strongholds in the Tornow-Klenica zone were liquidated. Staraya Ladoga and Wolin played a leading role in these relations. Both strongholds served as nodal points, where the forms of trans-Baltic shipping were combined with the inland navigation routes leading deep into both areas. The material culture of the communities of these settlements is also characterized by a number of similarities. Large buildings of post-and-plank construction were discovered there, erected at the end of the 9th and the beginning of the 10th century. The presence of large houses that stand out in the landscape of both centers is also perceptible in the second half of the 10th century. The material culture registered inside and in the vicinity of these wooden structures indicates that they could have been the seats of people involved in long-distance trade who can be regarded as “trade diasporas”. Their attributes included wooden anthropomorphic idols, balances and weights, and artifacts of Oriental origin. This article is an attempt to initiate a new Polish-Russian discussion on the cultural ties between the communities of Polish lands and Rus’ in the early Middle Ages.
Czy można mówić o działalności badawczej w warunkach nazistowskiego obozu koncentracyjnego? Uwagi na marginesie artykułu Andrzeja Prinkego
Authors: Leligdowicz Andrzej
Published: December 2022

In 2011, Przegląd Archeologiczny published an article by Andrzej Prinke discussing the wartime fate of Kazimierz Gelinek, the pre-war curator of the Masovian Museum in Płock, who was sent to the Nazi concentration camp in Gusen, but saved his life thanks to the archaeological research being conducted there by the SS. This interesting story was presented by the author as Gelinek’s research activity. However, he did not take into account the fact that Kazimierz Gelinek was primarily a forced labourer from the beginning to the end of his stay in the camp, whose combination of favorable circumstances made it possible to prepare an amateur study of archaeological excavations conducted in the area of the camp.