bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN FAKTOR RISIKO DENGAN KEJADIAN DIABETES MELLITUS DI PUSKESMAS DASAN TAPEN KABUPATEN LOMBOK BARAT
Authors: Fanani Ahkmad
Published: September 2022

Latar Belakang: Para ahli kesehatan juga menyebutkan diabetes mellitus merupakan penyakit yang terpaut kromosom sex atau kelamin. Biasanya kaum laki-laki menjadi penderita sesungguhnya sedangkan kaum perempuan sebagai pihak yang membawa gen untuk diwariskan kepada anak-anaknya. Banyaknya penderita diabetes mellitus dipengaruhi oleh beberapa faktor diantaranya adalah faktor usia, keturunan (genetika), obesitas dan kebiasaan merokok. Tujuan: untuk mengetahui hubungan faktor risiko (usia, keturunan, obesitas, kebiasaan merokok) dengan kejadian diabetes mellitus Metode: desain penelitian adalah penelelitian survey dengan pendekatan cross sectional. Instrumen yang digunakan dalam penelitian ini adalah kuesioner. Tekhnik pengambilan sample yang digunakan yakni accidental sampling dengan jumlah sampel sebanyak 52 orang. Analisa data yang digunakan adalah univariat dalam bentuk narasi, tabel distribusi frekuensi dan persentase, serta bivariat menggunakan tabulasi silang dan Uji Cochran's the Mantel-Haenszel statistic. Hasil: penelitian ini menunjukkan bahwa dari 52 responden pada faktor risiko umur diperoleh nilai p = 0,047 < α 0,05 sedangkan pada faktor risiko yang lain diperoleh nilai p= 0,000 < α 0,05, umur memiliki nilai odd ratio = 8.889 yang artinya seseorang yang berumur lebih dari 40 tahun memiliki risiko 8 kali, genetika memiliki nilai odd ratio = 21.538 yang artinya seseorang yang memiliki riwayat keturunan memilikzi risiko 21 kali, obesitas memiliki nilai odd ratio = 92.500 yang artinya seseorang yang mengalami obesitas memiliki risiko 92 kali, dan merokok memiliki nilai odd ratio = 23.400 yang artinya perokok memiliki risiko 23 kali. Kesimpulan: faktor usia, keturunan, obesitas, kebiasaan merokok memiliki hubungan dengan kejadian diabetes mellitus.
SINDROM METABOLIK DENGAN RIWAYAT KONSUMSI ALKOHOL MENINGKATKAN RISIKO TERJADINYA CHRONIC KIDNEY DISEASE: STUDI KASUS KONTROL DI RS PANTI NIRMALA KOTA MALANG
Authors: Ariyanti Rea
Published: September 2022

Chronic Kidney Disease (CKD) is a global public health problem with a high prevalence and incidence of kidney failure, poor prognosis, and has a large impact on morbidity, mortality, and socioeconomics of the community due to high treatment costs. Globally, CKD is the 12th leading cause of mortality and 17th for morbidity. There are several risk factors that are thought to increase the incidence of CKD, one of which is Metabolic Syndrome (SM). This study aims to determine the relationship between SM and the incidence of CKD at Panti Nirmala Hospital in Malang. The research design is case-control. The sample was 146 respondents, consisting of 73 case groups and 73 control groups. Data analysis using logistic regression. In the CKD group, the percentage of respondents with SM was 53.4% while in the group that did not suffer from CKD, the percentage of respondents with DM was 21.9%. It is known that after controlling for gender and age, respondents who have a history of consuming alcohol have an 11.9 times higher chance of developing CKD than respondents who do not have SM. It is recommended for the public to have regular health checks and change a healthy lifestyle, avoid consuming alcohol, and carry out regular health checks such as measuring blood pressure and blood sugar.
STIGMA DAN PERILAKU MASYARAKAT PADA TENAGA KESEHATAN DAN PENDERITA COVID-19 : LITERATURE REVIEW
Authors: Yuantari Maria Goretti Catur , Setyaningsih Sartika Wulan
Published: September 2022

ABSTRACTThe increase in Covid-19 cases raises various negative stigmas that develop in society, both inpatients and people with a high risk of being exposed to Covid-19, such as doctors, nurses, and other medical personnel. Stigma can appear in labeling, stereotyping, segregation, deprivation status, discrimination to people that are connected to Covid-19. This study aims to analyze the description of stigma and community behavior towards health workers and Covid-19 sufferers. The study method was a literature review with inclusion criteria in Indonesian or English, sourced from Proquest, PubMed, and Google Scholar from January-December 2020, which was available in full text, and using the keyword stigma among health workers and people with Covid-19. In this literature study, seven articles match the inclusion and exclusion criteria. From this literature review, it is known that the community carries various stigmas and behaviors towards health workers and Covid-19 patients with the causes and solutions that can be done. The negative stigma in Covid-19 patients and health workers must be nullified by optimal health literacy. The role of the government, health practitioners, and community leaders in providing education to the community regarding Covid-19 will help the community not attach a negative stigma to people affected by Covid-19.  Keywords : Behavior, Covid-19, Health Worker, Patient, Stigma ABSTRAK Peningkatan kasus Covid-19 memunculkan berbagai stigma negatif yang berkembang di masyarakat, baik pada pasien maupun orang dengan risiko tinggi terpapar Covid-19 seperti dokter, perawat, dan tenaga medis lainnya. Stigma muncul dalam bentuk pemberian label, stereotip, pemisahan, penghilangan status dan diskriminasi pada orang yang berhubungan dengan Covid-19. Penelitian ini bertujuan untuk menganalisis lebih dalam gambaran stigma dan perilaku masyarakat pada tenaga kesehatan dan penderita Covid-19. Metode penelitian yang digunakan adalah literature review dengan kriteria inklusi bahasa Indonesia atau bahasa Inggris, bersumber dari Proquest, PubMed, dan Google Scholar sejak Januari - Desember 2020, tersedia dalam fulltext, dan menggunakan kata kunci stigma pada tenaga kesehatan dan penderita covid-19. Pada studi literatur ini didapatkan 7 artikel yang sesuai dengan kriteria inklusi dan ekslusi. Dari tinjauan artikel ini di ketahui bahwa muncul berbagai stigma dan perilaku yang dilakukan masyarakat pada tenaga kesehatan maupun penderita Covid-19 beserta penyebab muncul dan proses penyelesaian yang dapat dilakukan. Stigma negatif pada penderita Covid-19 dan tenaga kesehatan harus dihilangkan dengan literasi kesehatan dari berbagai pihak. Peran dari pemerintah, praktisi kesehatan, dan tokoh masyarakat dalam memberikan edukasi pada masyarakat terkait Covid-19 akan membantu masyarakat untuk tidak melekatkan stigma negatif kepada orang yang terkena Covid-19.Kata kunci       : Covid-19, Pasien, Perilaku, Stigma, Tenaga kesehatan
HUBUNGAN ANEMIA DAN KEKURANGAN ENERGI KRONIK PADA IBU HAMIL DENGAN BERAT BADAN BAYI BARU LAHIR
Authors: Indrasari Oktovina Rizky
Published: September 2022

Anemia during pregnancy hurts both mother and baby. The research objective was to analyze the relationship between anemia and chronic energy deficiency in pregnant women with the incidence of new birth weight. This study used a cross-sectional research design. The population in this study were the third-trimester pregnant women in the working area of Ngadiluwih Public Health Center, Kediri Regency. The sample in this study was 52 respondents. The sampling technique used was total sampling. The results of the chi-square test showed the relationship between anemia and weight of newborns had a p-value of 0.001. It shows that there is a correlation between anemia in pregnant women and the incidence of newborn body weight with PR 21.5, which means that mothers who experience anemia during pregnancy have a 21.5 times greater risk of giving birth to babies with low birth weight than mothers who are not anemic. The association of chronic energy deficiency with newborn body weight has a p-value of 0.000. It shows that there is a relationship between chronic energy deficiency and newborn weight with PR 15.6, which means that mothers who experience chronic energy deficiency have a 15.6 times greater risk of giving birth to western babies with low birth weight than mothers who do not experience chronic energy deficiency. During pregnancy, pregnant women consume foods that contain iron and iron supplements.
EFEKTIVITAS PENERAPAN PAY-FOR-PERFORMANCE PADA ASURANSI KESEHATAN DI NEGARA-NEGARA ASIA: LITERATURE REVIEW
Authors: Subur Slamet , Rachmawaty Rini , Saleh Ariyanti
Published: September 2022

Public health insurance programs have become a global concern, especially in program planning such as resource use, knowing the effectiveness of pay-for-performance implementation in health insurance in Asian countries. Method Research design is a library study. Search for articles using the Pubmed, Ebsco, ScienceDirect, and Proquest databases. The research questions are structured using the PICO method, a database-based keyword search in MESH terms. Inclusion criteria are focused on the application of Pay-for-performance, on health insurance, applied in Asian countries, issued the last 10 years, in English. Found 748 articles, and only 9 articles were included according to research questions. Result: There are 9 articles included in this study. The results of a critical review of published articles, the application of pay-for-performance on health insurance in Asian countries improve the achievement of indicators, incentives and payment fines, and improve the quality of health services. Conclusion The application of Pay-For-Performance to health insurance in Asian countries is based on various indicators, payment systems, and improved quality of health services. Therefore, the application of Pay-For-Performance can be recommended for healthcare facilities in Asian countries.
PERSEPSI, KOMPETENSI DAN HAMBATAN PERAWAT DALAM PEMENUHAN SPIRITUAL CARE PASIEN: LITERATURE REVIEW
Authors: Tunny Hasna , Saleh Ariyanti , Rachmawaty Rini
Published: September 2022

Spiritual care is care given to meet the spiritual needs of patients, but many patients state that they do not receive spiritual support from the medical team. This is because nurses' perceptions of spirituality and spiritual care are lacking, competence is not adequate and there are obstacles in meeting the spiritual needs of patients. So this review aims to identify the perceptions, competencies and barriers of nurses in fulfilling spiritual care. Method by Literature review research design. Search articles on PubMed, ClinicalKey for Nursing, and ProQues by keyword based on PICO. Found 1,839 articles in the period 2015-2021 (May), then screening was carried out and found 20 relevant articles to be discussed and analyzed. Results The majority of nurses have a moderate-good perception of spiritual care, nurses' competence is at a moderate-good level. Barriers found, lack of knowledge, inadequate skills, heavy workload, time constraints, lack of intimacy in providing spiritual care, cultural differences and lack of hospital management support. Conclusions nurses have positive perceptions, moderate-good competition and obstacles in fulfilling spiritual care. Spiritual care education or training is needed in order to increase self-awareness about spiritual nurses in fulfilling spiritual care for patients.
PREVALENSI ADOLESCENT IDIOPATHIC SCOLIOSIS : LITERATURE REVIEW
Authors: Ramadhani Alinda Nur , Romadhoni Dea Linia
Published: September 2022

Adolescent idiopathic scoliosis is a musculoskeletal disorder characterized by three-dimensional changes in the vertebrae that occur in children aged 10-18 years. The purpose of this study was to determine the prevalence of adolescent idiopathic scoliosis through a literature review. Research article searches were carried out in the PubMed and BMC Central databases using the keywords “adolescent”, “idiopathic”, “prevalence” and “prevalence” from 2010 to 2020. Articles in English and Indonesian were selected using keywords, and 389 articles were found. The articles were then selected based on the exclusion and inclusion criteria, leaving 5 articles to be reviewed. The prevalence of adolescent idiopathic scoliosis is higher in girls than boys and the prevalence increases with age. The prevalence of adolescent idiopathic scoliosis varies between 0.72-4.3%.
EFEKTIVITAS TERAPI OKSIGEN HIPERBARIK (HBOT) TERHADAP PENYEMBUHAN LUKA KAKI DIABETIK: LITERATURE REVIEW
Authors: Selvia Heni , Syam Yuliana , Yusuf Saldy
Published: September 2022

Diabetic Foot Ulcer (DFU) is one of the complications that cause big problems in diabetics. One of the management of DFU management is by utilizing hyperbaric oxygen therapy (HBOT) which is an additional therapy that has been proven to be used in the treatment of DFU. However, the results of its benefits and use are still being debated, so the purpose of this review is to evaluate the effectiveness of HBOT on healing diabetic foot wounds. The method of this research is to use a literature review design. By using three international databases, namely PubMed, Science Direct, and Ebscohost, six articles were included. The results of the review explained that from six articles conducted by the literature review, it was reported that hyperbaric oxygen therapy (HBOT) can accelerate the healing process of diabetic foot wounds (DFU), by reducing wound size, lowering levels of C-reactive protein (CRP) and white blood cells (WBC)), induces angiogenesis of EGF, VEGF, PDGF, FGF-2 and CXCL10 and changes serum interleukin 6 (IL-6) and VEGF levels to be greater. Conclusion (HBOT) is an appropriate adjunct therapy, which can provide effectiveness in the treatment of DFU by accelerating the healing of DFU and preventing further infection in DFU, so as to reduce the risk of amputation.
PENGARUH KUALITAS TIDUR TERHADAP KADAR HEMOGLOBIN CALON PENDONOR DI UTD PMI KABUPATEN SIDOARJO
Authors: Ariani Nia Lukita , Sudiwati Ni Luh Putu Eka , Panggayuh Ardi , Khofifah Khumairotul
Published: September 2022

Tidur merupakan kebutuhan penting bagi setiap individu. Kualitas tidur yang kurang baik berakibat pada penurunan kadar hemoglobin dalam tubuh. Kadar hemoglobin merupakan syarat penting pada proses donor darah. Tujuan penelitian yaitu untuk mengetahui pengaruh kualitas tidur terhadap kadar hemoglobin calon pendonor di UTD PMI Kabupaten Sidoarjo. Metode penelitian ini menggunakan desain cross sectional. Responden dipilih menggunakan teknik simple random sampling dan diperoleh responden sebanyak 96 orang. Data kualitas tidur diperoleh melalui pengisian kuesioner Pittsburgh Sleep Quality Index (PSQI) oleh calon pendonor dan pemeriksaan kadar hemoglobin menggunakan Diaspect Hb meter. Hubungan kedua variabel diuji menggunakan Chi Square. Ada hubungan antara kualitas tidur dengan kadar hemoglobin dengan hasil nilai p= 0,00 (0.05). Responden yang kualitas tidurnya kurang baik, lebih banyak memiliki kadar hemoglobin rendah dibandingkan responden dengan kualitas tidur baik. Faktor genetik, jenis kelamin, usia, etnis, ketinggian tempat, penyakit yang diderita, obat yang sedang dikonsumsi, dan status nutrisi adalah faktor lain yang juga mempengaruhi kadar hemoglobin.
Analisis Determinan Keikutsertaan WUS Dalam Pemeriksaan IVA Untuk Deteksi Dini Kanker Serviks Dengan HBM
Authors: Octaliana Hasrita , Wathan Fika Minata , Aisyah Siti , Januar Rico
Published: September 2022

Kanker  serviks  adalah  kanker  paling  umum  kedua  pada  wanita  yang  tinggal  di  negara berkembang yang berpenghasilan rendah dan merupakan kanker yang disebabkan oleh Human Papilloma Virus (HPV). WHO telah meninjau bukti mengenai kemungkinan modalitas untuk skrining kanker serviks dan telah menyimpulkan bahwa skrining harus dilakukan setidaknya sekali untuk setiap wanita dalam kelompok usia sasaran (30-49 tahun) dan test HPV, sitologi dan Inspeksi Visual Asam Asetat (IVA) adalah tes skrining yang direkomendasikan. Jenis penelitian ini adalah deskriptif analitik dengan desain cross sectional yang dilakukan di wilayah kerja Puskesmas Sungai Lokan terhadap 170 responden. Pengambilan sampel menggunakan metode accidental sampling. Pengambilan data menggunakan kuesioner dan data dianalisis menggunakan uji Chi-square dan regresi logistik. Hasil penelitian menemukan bahwa terdapat hubungan signifikan antara usia, tingkat pendidikan, kerentanan, ancaman, hambatan, dan isyarat bertindak dengan keikutsertaan pemeriksaan IVA dengan nilai p 0,05, namun tidak terdapat hubungan pengetahuan, keparahan, dan manfaat dengan keikutsertaan pemeriksaan IVA dengan nilai p0,05. Faktor paling dominan berhubungan dengan keikutsertaan pemeriksaan IVA adalah kerentanan yang dirasakan baik memiliki peluang 200,870 kali untuk melakukan pemeriksaan IVA. Ada hubungan antara umur/usia, tingkat pendidikan, kerentanan, ancaman,   dengan keikutsertaan pemeriksaan IVA di Wilayah Kerja Puskesmas Sungai Lokan Kecamatan Sadu Kabupaten Tanjung Jabung Timur Tahun 2020.
Factors Related To Self-Care Activities In The Elderly With Diabetes Mellitus In Bener Meriah Regency
Authors: Fati Lina , Asniar Asniar , Susanti Suryane Sulistiana
Published: September 2022

The number of Diabetes Mellitus (DM) survivor were continuously increasing, especially among the elder population. This study aims to identify any factors associated with self-care activities in the elder with DM, also the relationship between knowledge, self-efficacy, and family support to the self-care activities in such population. The data were collected using a questionnaire and analyzed using SPSS for univariate, bivariate (Pearson), and multivariate (logistic regression) techniques. The results indicate that there was a relationship between knowledge and self-care activities in the elder with DM (0.000 0.05), and there was no relationship between self-efficacy and self-care activities (0.824 0.05). Moreover, a significant relationship showed between knowledge and self-care activities (0.000 0.05), and based on the linear regression test results, this research concluded that family support (0.000 0.05) become the most decisive factor and influence on self-care activities in the elder with diabetes mellitus in Bener Meriah
Overview of Hemodialysis Nurse Services During The Covid-19 Pandemic in Indonesia 2021
Authors: Melati Nimsi , Yekholya Indri , Natanael Natanael , Omega Nova , Kondo Yovita
Published: September 2022

Chronic Kidney Failure (CKD) is a disease that has a high incidence in Indonesia. End-stage CKD conditions require hemodialysis therapy at least 1-2 times every week with the help of HD nurses. The second explosion of Covid-19 cases occurred in the middle of 2021 affecting condition of nurses. Preliminary studies show that there is a difference in the care provided by nurses during pandemi. The purpose of this study was to find out description of hemodialysis nurse services during Covid-19 pandemi in Indonesia. Research method was qualitative design with a phenomenological approach. Sampling technique was purposive sampling. Population in this study were hemodialysis nurses. Sample of this study was 5 participants who came from various type B private hospitals. Results of this study are 4 themes: HD services are carried out with strict health protocols and special HD device care, limited duration of communication bring dissatisfaction for nurses and patients, nurses always prepare themselves mentally and physically before working, hope for the passing of the pandemi, patient honesty and adequate manpower are the main things for nurses. Conclusion: hemodialysis nurse services during covid-19 pandemi have been carried out with strict health protocols and nurse readiness is better at this time.
Self-Efficacy Pada Ibu Hamil Dengan Tingkat Kecemasan Selama Masa Pandemi Covid-19 Di Ruteng
Authors: Padeng Eufrasia Prinata , Senudin Putriatri Krimasusini , Laput Dionesia Octaviani , Trisnawati Reineldis Elsidianastika
Published: September 2022

Kecemasan yang dialami ibu hamil disebabkan oleh berbagai faktor. Hal ini akan berdampak pada kesehatan ibu dan janin. Efek yang akan terjadi pada ibu hamil yang mengalami kecemasan selama masa kehamilan akan terjadi prematur dan depresi pasca persalinan. Tujuan penelitian menganalisis pengaruh kecemasan saat kehamilan dan juga mengatasi dampak yang terjadi akibat kecemasan baik bagi janin maupun bagi ibu. Dalam Penelitian ini penulis  menggunakan rancangan penelitian Kuantitatif dengan desain penelitian survey analitik pendekatan  cross sectional. Populasinya adalah seluruh ibu hamil sejumlah 52 orang. sampel dalam penelitian dimaksud adalah sebesar 30 orang dan teknik pengambilan samplingnya Purposive Sampling. Uji Statistik yang digunakan adalah Chi Square.Pada penelitian ini instrumen pengumpulan data yang digunakan adalah kuesioner data Demografi, kuesioner General Self Efficacy dan kuesioner Hamilton Anxiety Rating Scale (HARS). Berdasarkan hasil penelitian didapatkan bahwa selama masa pandemi COVID-19 sebagian besar ibu hamil mengalami kecemasan Berat dan self efficacy tingkat  sedang  yaitu sebesar 11 orang (55%). Terdapat pengaruh self efficacy yang sedang terhadap kecemasan ibu hamil selama masa pandemi COVID 19 dengan nilai p valuenya adalah   0.05. Semakin kurangnya percaya diri dari ibu hamil maka kecemasan juga akan selalu dialaminya selama masa pandemi. Kecemasan yang terjadi bisa menyebabkan kondisi ibu maupun janin menurun.. Saran dalam penelitian ini adalah bagi peneliti selanjutnya diharapkan untuk menggali lebih dalam lagi terkait pencegahan kecemasan dalam kehamilan serta ditambahkan variabel penelitian.
Pengetahuan dengan Sikap Ibu tentang Kejadian Kejang Demam Pada Anak Di Rumah Sakit Panti Waluyo Sawahan Malang
Authors: Hastutiningtyas Wahidyanti Rahayu , Maemunah Neni , Susmini Susmini
Published: September 2022

Demam yang mengakibatkan kejang  pada anak dimana keadaan ini merupakan  gangguan neurologik pada anak yang berusia 6 bulan - 5 tahun. Ibu memerlukan pengetahuan lebih tentang kejang demam pada anak karena dapat membantu anak mengatasi masalah penyakitnya, hal ini adalah peran penting yang harus ada pada seorang ibu. Ibu juga harus menjadi siaga ketika anak mengalami kejang demam. Tujuan penelitian yaitu melihat hubungan Pengetahuan dengan Sikap Ibu dengan Kejadian Kejang Demam Pada Anak Di Rumah Sakit Panti Waluyo Sawahan. Desain pada penelitian yaitu observasi analitik dengan cross sectional. Instrumen adalah kuesioner telah dimodifikasi. Teknik sampling yaitu simple random sampling, populasi sejumlah 60 responden dan sampel sebanyak 50 responden. Hasil analisis data yaitu uji spearman-rank dan ada hubungan  pengetahuan dengan sikap ibu tentang kejadian kejang demam pada anak di Rumah Sakit Panti Waluyo Sawahan dengan nilai p = 0,014 (p0,05) dan r = 0,345. Penelitian ini menjadi sumber informasi dalam melakukan penelitian selanjutnya dan menjadi pedoman pembelajaran serta menambah wawasan dan informasi mengenai pengetahuan dan sikap ibu tentang kejang demam.
Dukungan Keluarga dan Mekanisme Koping Berhubungan Dengan Kecemasan Lansia
Authors: Putri Ronasari Mahaji , Devi Hilda Mazarina
Published: September 2022

Fenomena tingginya kejadian kecemasan pada lansia masih belum tertangani. Kondisi lansia seringkali dihubungkan dengan rendahnya mekanisme koping lansia dan rendahnya dukungan keluarga lansia. Masalah kompleks ini akan menyebabkan kualitas hidup lansia memburuk Penelitin bertujuan menghubungkan dukungan keluarga, mekanisme koping dengan kecemasan pada lansia. Tujuan penelitia mengetahui hubungan self efficacy dengan kejadian depresi lansia. Merupakan penelitian observasional, desain crossectional. Populasi yakni seluruh lansia di RT X dan RW Y Kelurahan Tlogomas berjumlah 30 orang, dengan sampel diambil dengan teknik total populasi. Kriteria inklusi adalah pasien lansia yang mengalami kecemasan. Dukungan keluarga dan mekanisme koping adalah variabel bebas, dan  tingkat kecemasan variable terikat. Instrumen dukungan keluarga berupa kuesioner yang diadopsi dari Liandi (2011),  mekanisme koping serta instrument kecemasan menggunakan kuesioner HARS. Analisa data menggunakan uji chi square. Hasil penelitian menunjukkan sebagian besar  lansia mempunyai dukungan keluarga kurang (63,8%), mekanisme koping lansia kurang (70,0%), dan tingkat kecemasan berat (53,3%). Uji statistik menunjukkan kaitan dukungan keluarga dan mekanisme koping dengan tingkat kecemasan lansia (p value = 0,000).
Hubungan Kepatuhan Orang Tua Terhadap Protokol Kesehatan Dengan Status Kesehatan Pada Balita
Authors: Susmini Susmini , Cahyaningrum Ika
Published: September 2022

Pandemi Covid-19 yang berlangsung sejak awal 2019, mengakibatkan banyak perubahan hampir semua tatanan kebiasaan di antaranya dalam hal kesehatan. Kepatuhan dalam melaksanakan  Protokol Kesehatan menjadi sangat penting di lakukan untuk menghentikan pandemi tersebut. Tujuan  penelitian ini untuk mengetahui hubungan kepatuhan orang tua terhadap protokol kesehatan dengan status kesehatan pada balita. Desain penelitian ini menggunakan deskriptif korelatif  dengan pendekatan cross sectional. Jumlah sampel 30 orang dengan tehnik pengambilan sampling adalah total sampling, penelitian ini di lakukan di klinik mandiri perawat Desa Sukodadi Kecamatan Wagir. Berdasarkan uji statistik Spearmen didapatkan hasil nilai α 0,05 (0.000), dengan nilai Correlation Coefficient 0. 641 artinya ada hubungan kuat antara tingkat kepatuhan orang tua terhadap protokol kesehatan dengan status kesehatan pada balita. Bagi perawat sebagai  educator   harapannya dapat memberikan edukasi tentang pentingnya penerapan protokol kesehatan sebagai upaya pengendalian dan pencegahan penyebaran virus Covid-19.
Harga Diri Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik (GGK) Yang Menjalani Hemodialisa Pada Masa Pandemi Covid-19
Authors: Ngara Yohanes Wolla , Rosdiana Yanti , Rahayu Wahidyanti
Published: September 2022

Pasien gagal ginjal yang menjalani hemodialisa biasanya akan mengalami beberapa perubahan biologis, social ldan spiritual ditambah lagi masa covid-19 ini, tentunya akan berdampak  pada harga dirinya serta kualitas hidupnya. Adapun tujuan dalam penelitian ini untuk mengetahuiphubungan harga diri pdengankualitashidup pada pasien gagal ginjal kronik yang menjalani hemodialisa pada masa pandemi covid-19. Penelitian ini menggunakan desain observasi analitik dengan cross sectional, populasi dalam penelitian ini merupakan semua pasien gagal ginjal kronik yang menjalani hemodialisa sebanyak 96 orang dengan jumlah sampel sebanyak  36 orang. Variabel independen dalam penelitian ini yaitu harga diri, sedangkan variabel dependennya adalah kualitas hidup. Instrumen yang digunakan untuk harga diri adalah self esteem scale dan untuk kualitas hidup menggunakan kuesioner The World Health Organization Quality of Life (WHOQoL)-BREF. Analisis data menggunakan univariat dan bivariat dengan uji Chi Square. Hasil Penelitian menunjukkan bahwa harga diri rendah akan memiliki kualitas hidup kurang pada pasien gagal ginjal kronik (GGK) yang menjalani hemodialisa pada masa pandemi covid-19 dengan nilai (P-value = 0,006). Diharapkan untuk penelitian selanjutnya untuk dapat menggali psikologis yang dirasakan oleh pasien gagal ginjal kronis pada masa pandemic covid-19.
A bi-objective model for determining an optimal warehouse capacity, and product allocation in a green multi-product, multi-period distribution network
Authors: Jinawat Krit , Tai Pham Duc , Buddhakulsomsiri Jirachai
Published: September 2022

Nowadays, the growing trend of environmental concerns is significantly higher than in the past while the business also focuses on the supply chain more to serve the customer demand using the lowest resources possible which leads to two main decisions which are capacity, and product allocation. Therefore, this research aims at designing a multi-product, multi-period, and multi-echelon supply chain network with factories, internal warehouses, external warehouses, and customers while also trying to lower the environmental effect of the supply chain through gas emission. For this problem, large data of products and 20 periods of planning horizon of a real-world polymer industry are considered. The product deliveries use direct shipment from both internal and external warehouses. We develop bi-objective mixed-integer linear programming to find the most optimal product allocation and capacity while minimizing the total logistic costs which include warehouse and transportation cost and total  emission through transportation. The problem is solved by the min-max approach through a mixed integer linear programming model using CPLEX software. After we get the result, we compare it with the single-objective model’s result to determine the trade-off between the total logistic cost and emission gas. Our base case result shows a better overall satisfaction level among all the models.
Audit In the Russian Federation: Quality Assessment Problems
Authors: Erokhina Ekaterina , Motolyanets Marina
Published: September 2022

The aim of the research is to develop a methodology for assessing the quality of audit, which is currently absent in Russian audit practice. The key difference between the methodology is simplicity of calculations, functional and personnel costs for calculations and data analysis. In the course of the study, an algorithm was proposed for conducting an audit quality assessment procedure and calculating an audit quality factor aimed at public declaration of a responsible audit business.
Digital Business Strategy’s Optimisation Model for Differential Value Creation in the Digital Age
Authors: Okanga Boniface
Published: September 2022

In the age where every firm is digitizing, it is no longer digitisation that leverages a firm’s competitive edge. Instead, it is the know-how of digital business strategy’s optimisation which is increasingly turning into an idiosyncratic strategic value creating resource. But even if that is the case, discerning how to bolster digital business strategy’s optimisation is still a paradox as most of the previous studies have been largely fascinated with digital transformation as a driver of digitisation. As this undermines how firms can discern how to optimise their digital business strategy, it is such a paradox that this paper sought to address by exploring a model for leveraging digital business strategy’s optimisation as a driver of differential value creation. The paper uses interpretivist research paradigm, exploratory research design and qualitative research method to explore and socially construct the opinions of sixty-six digital business managers and IT managers from the energy and chemical sector about the approaches for digital business strategy’s optimisation as well as its impact on value creation and major impediments among the multinational companies in the global energy and chemical industries. The sixty-six digital business managers and IT managers were purposively drawn from eighty multinational energy and chemical companies that are operating in South Africa, Uganda and Nigeria. Apart from investment in relevant digital technologies and digital transformation, findings revealed factors that leverage or even constrain digital business strategy’s optimisation to create differential values to often arise from how the digital business strategy is crafted and utilised as well as digital skills and level of digital culture transition. Such findings contrast theories that indicated strategic levers of digital business strategy’s optimisation to include scope, scalability, speed and sources of value creation of the digital business strategy. However, in conclusion, the paper proposes an alternative digital business strategy’s optimisation model that executives can replicate as an idiosyncratic strategic value creating resource to leverage a firm’s competitiveness in the modern complex digital age.
Guttural pouch empyema in a Mangalarga Marchador filly: Case report
Authors: Oliveira Morgana de , Santos Fernanda Carlini Cunha dos , Weiler Gabriel , Salvador Flávia Renata Crema , Paula Iury Ribeiro de , Schuch Luiz Fernando , Bondan Carlos , Alves Leonardo Porto
Published: September 2022

Guttural pouch empyema is usually a consequence of upper respiratory tract infections, especially those caused by Streptococcus equi. In adult horses, empyema is a common disease, whereas considered rare in foals. The aim of this work was to report a case of unilateral guttural pouch empyema in a filly, with a focus on diagnostic and treatment approaches. A 1-month-old filly, 68 kg, Mangalarga Marchador, was admitted because of respiratory distress and enlargement caudally in the head. Clinical examination revealed dyspnea, dysphagia, lymphadenopathy, unilateral enlargement in the retropharyngeal area, and mucopurulent nasal discharge. Further, endoscopic examination confirmed the presence of purulent material inside the left guttural pouch and a diagnosis of empyema was arrived at. Drainage was performed surgically, a catheter was inserted for guttural pouch lavage. The animal received bromexin, dexamethasone, flunixin meglumine, ceftiofur, probiotics, vitamin complexes, and ringer lactate solution. Hematological evaluation performed every 24-72h, showed a decrease in total leukocytes, fibrinogen, platelets, total plasma protein, hematocrit, hemoglobin, and erythrocytes. Eleven days after drainage, the filly’s clinical condition was stable and the wound has healing. The animal was discharged following a good prognosis. Differential diagnoses can include other respiratory diseases, such as guttural pouch timpanism, strangles, and Rhodococcus, which are excluded due to the clinical signs and complementary examinations. In the present case early diagnosis, based on physical examination, hematological parameters, and radiography, combined with adequate treatment methods, including surgical procedures, lavages, antibiotics, and anti-non-steroidal inflammatory therapy, contributed to resolving the guttural pouch empyema in the filly.
Doença do olho seco na era COVID-19: uma revisão de escopo
Authors: Regis Beatriz Cavalcanti , Fernandes Ariadne Sampaio Toledo , Pol-Fachin Laércio , Gonçalves Daniela Sampaio Silva
Published: September 2022

O presente estudo busca correlacionar o uso da máscara facial e dispositivos eletrônicos na era COVID-19 com o surgimento ou agravamento da doença do olho seco. Bancos de dados online foram usados para identificar artigos publicados em 2020 e 2021, através dos descritores “dry eye syndromes”, “covid-19”, “diagnosis” e “asthenopia” encontrados no MeSH (Medical Subject Headings), associados ao operador booleano AND. Após a leitura dos títulos, resumos e textos na íntegra, dezessete artigos foram selecionados para compor o trabalho. Além disso, por indicação de especialista, o maior estudo mundial sobre doença do olho seco, TFOS DEWS II, publicado no Ocular Surface Journal em julho de 2017, também foi somado a esta revisão. Foi constatado que a duração média de uso dos dispositivos eletrônicos triplicou na era COVID, e apenas duas horas contínuas desenvolvem fadiga ocular digital, pois piscadas diminuídas e incompletas levam ao comprometimento da superfície ocular e sintomas astenópicos. Além disso, a vedação inadequada da máscara dissipa o ar ao redor dos olhos, causando rápida evaporação do filme lacrimal e exposição da córnea. Diante dos estudos, pode-se concluir que a correlação entre os fatores apresentados e a doença do olho seco realmente existe. Além disso, a manifestação ocular mostrou-se heterogênea e afeta não somente aspectos da saúde física como também da saúde emocional e impacta negativamente a qualidade de vida do paciente.
Prevalence and consequences of molar incisor hypomineralization in a São Paulo state public school
Authors: Takahashi Karine , Sassi Mariali Muniz , França Mariana Meira , Araujo Heitor Ceolin , Vilhegas Sérgio , Barbieri Cintia Medid
Published: September 2022

Objective: This work aims to determine prevalence and consequences of Molar Incisor Hypomineralization in the city of Ouro Verde – SP. Methodology: 457 children, students from the municipal school EMEF Julia Roseira Jerônimo were examined, aging from 7 to 11 years old. Clinical examinations for the diagnosis were performed by a single trained and calibrated examiner using the criteria proposed by the European Academy of Pediatric Dentistry (EAPD, 2009) using natural light and wood spathulas. Result: The index found in the city was 15% of students (79 affected children) and only one case with sensitivity. Conclusion: prevalence was significative, although symptoms related were rare.
Antimutagenic effects of copaiba oils (Copaifera langsdorffii Desf.) and flaxseed (Linum usitatissimum L.) against the clastogen – cyclophosphamide, in Wistar rat
Authors: Heck Michele Cristina , Yoshimoto-Higaki Mariana , Godoy Mariane Aparecida Franco de , Mendonça Debora Elisa Antunes de , Vicentini Veronica Elisa Pimenta
Published: September 2022

Copaiba oil extracted from the trunk of Copaifera langsdorffii Desf. and flaxseed oil extracted from the seeds of Linum usitatissimum L., are widely used for the prevention and treatment of many diseases, including cancer. The aim of this study was to assess the antimutagenic effect of these oils against the damage-inducing agent cyclophosphamide, in Rattus norvegicus treated in vivo, by gavage, using cytotoxicity and chromosomal alteration test. The animals were submitted to a single dose of copaiba oil and of flaxseed oil in the simultaneous treatment, pre-treatment and pos-treatment for 24 hours. None of these treatments presented cytotoxic effect. Treatments both oils and cyclophosphamide have significantly reduced the chromosomal damage caused by the clastogen. In groups treated with copaiba oil the reduction percentage was 77% for the simultaneous treatment, 83% for the pre-treatment and 75% for the pos-treatment, whereas in those treated with flaxseed oil was 94% for the pre-treatment and 96% for the simultaneous and pos-treatment. These results indicate that the both oils are not mutagenic, in contrast, they present antimutagenic activity against this clastogenic agent, which represents a protective effect on the cells against the drug that has damaged the genetic material.
Ompk36 disruption and expression of down-regulated blaKPC-2 in Klebsiella pneumoniae clinical isolates carbapenem resistant
Authors: Souza Paula Mariana Salgueiro de , Ribeiro Ana Caroline Oliveira Alves , Morais Márcia Maria Camargo de , Almeida Anna Carolina Soares
Published: September 2022

This work investigated the resistance mechanisms that produce different susceptibility profiles in Klebsiella pneumoniae clinical isolates. The genes that encode the main porins in K. pneumoniae, ompK35 and ompK36, and several beta-lactamase genes were analyzed. The expression of these genes was evaluated by quantitative real time PCR (polymerase chain reaction) with reverse transcriptase (RT-qPCR). SDS-PAGE (sodium dodecyl sulphate–polyacrylamide gel electrophoresis) was performed to analyze the outer membrane proteins. The analysis of the ompK36 genetic environment found the presence of the IS903 insertion sequence interrupting this gene in the ertapenem resistant isolate (KPN133). The blaKPC-2 gene showed down-regulated expression in both isolates.
A possível citotoxicidade desenvolvida pelo uso de ivermectina em pacientes com COVID-19: uma revisão integrativa
Authors: Silva Danieli Henriques da , Orozco Darling Lorena Barros , Coroa Eduardo , Coêlho Katiane  Alexandre Alves , Baia Rayane , Valente Ricardo Leão , Guimarães Marcia
Published: September 2022

Objetivo: Analisar a literatura científica que trata da possível citotoxicidade desenvolvida pelo uso de ivermectina em pacientes com COVID-19: uma revisão integrativa. Métodos: Trata-se de uma revisão integrativa de literatura, delineado como um estudo observacional, transversal e qualitativo, realizou-se a coleta de dados a partir de fontes literárias e cientificas recentes, do ano de 2020 até o ano de 2022. Resultados: A metabolização da ivermectina ocorre no fígado, apresenta uma meia vida média de quatro vezes maior do que outros fármacos, grande potencial hepatóxico. As comprovações cientificas para sua utilização, se deram com base em pesquisa in vitro, o que apresenta resultados insuficientes para determinar sua segurança e eficácia. Constatou-se que 05 dias de tratamento com ivermectina, era um tempo seguro para apresentar resultados eficazes, com uma dose de 0,4 - 0,6mg/kg por dia. Identificou-se as interações de candidatos a medicamentos ante – COVID 19 com transportadores hepáticos, esses fármacos, têm múltiplos efeitos inibitórios nos transportadores de membrana hepática e podem causar toxicidade e afetar a farmacocinética. Conclusão: Evidencia-se a imprecisão de dados sobre o uso terapêutico da ivermectiva, juntamente a informações de baixa qualidade para orientação clínica, no que diz respeito ao uso, dosagem e duração do tratamento. Quanto ao possível efeito citotóxico da Ivermectina em pacientes com covid-19, não teve estudos clínicos para evidenciar tal resultado, porém, o seu uso é contraindicado devido à escassez de dados. Portanto, a realização de mais ensaios clínicos randomizados são necessários para determinar o nível de toxicidade da ivermectina no tratamento da SARS-CoV-2.
Compensação Ambiental de Supressão de vegetação no Licenciamento de Pequenas Centrais Hidrelétricas em Minas Gerais
Authors: Almeida Maria Rita Raimundo e , Ferreira Matheus Lemes do Vale , Veronez Fernanda Aparecida
Published: September 2022

A exploração dos recursos ambientais por parte da humanidade sempre existiu, sendo a supressão de vegetação das mais recorrentes. A mobilização social pela questão ambiental fez com que surgisse o mecanismo de compensação ambiental, que visa balancear os impactos negativos de um projeto que não puderam ser evitados ou mitigados. A proposta de compensação ambiental deve obedecer a três princípios: proporcionalidade (relação entre dano causado e compensação), conexão espacial (deve estar próxima ou na mesma bacia hidrográfica da área impactada) e conexão funcional (deve promover a reposição/substituição das funções ecológicas perdidas). Este trabalho avalia como a compensação ambiental de supressão de vegetação é apresentada nos Estudos de Impacto Ambiental de Pequenas Centrais Hidrelétricas em Minas Gerais. Foram analisados todos os seis casos identificados no sistema de licenciamento do estado, entre 2018 e 2021. Os dados foram analisados utilizando pesquisa documental e análise de conteúdo dos estudos, sendo aplicado três critérios baseados nos princípios da compensação, avaliados como “atendido”, “parcialmente atendido” e “não atendido”. Os resultados indicam que apenas dois estudos atenderam integralmente os critérios adotados, sendo que a conexão funcional e a proporcionalidade apresentaram, respectivamente, os melhores e piores resultados. Tal panorama revela a falta de detalhamento das informações apresentadas nos estudos e a necessidade de aprimoramento. Um resultado alarmante é que em quatro dos cinco casos aplicáveis, a Lei da Mata Atlântica não foi cumprida em sua totalidade. Espera-se que este estudo possa contribuir para o aperfeiçoamento do mecanismo, bem como auxiliar na legislação ambiental brasileira.
Fadiga em pacientes com câncer em tratamento radioterápico
Authors: Viana Bruno Leonardo Almeida , Carvalho Ana Flávia Machado de , Marinho Fernando Antônio Madeira
Published: September 2022

O câncer é a doença que mais mata pessoas no mundo, mais da metade de casos por ano vão a óbito, contudo existem diversos tratamentos em busca da melhoria e qualidade de vida dos pacientes oncológicos como a cirurgia, quimioterapia, radioterapia etc. Todos esses tratamentos levam os pacientes a terem fadiga, já que destroem tanto as células boas quanto as ruins, e na maioria dos casos as boas se regeneram, as cancerígenas não. Destarte, iniciando-se os efeitos colaterais. Portanto, o objetivo do presente artigo é descrever a fadiga em pacientes que fazem radioterapia e explicar quais métodos podem aliviá-la. A metodologia utilizada é a revisão bibliográfica e integrativa, com uma abordagem qualitativa e o método de análise de Bardin. Assim, as causas da fadiga provêm do tratamento escolhido e do local do tumor. Conclui-se que, a melhor forma de tratar a fadiga é buscando alternativas para diminuí-la, dentre elas a prática de exercícios físicos diários e abster-se do dispêndio de energia.
Educação ambiental e a Ecoescola: Instrumentos imprescindíveis para o desenvolvimento sustentável
Authors: Conceição Gyselle dos Santos , Brasil Davi do Socorro Barros , Corrêa Solange Maria Vinagre , Nascimento Fabiana Cristina de Araujo , Conceição Silvio dos Santos , Oliveira Josiane Macedo de , Chagas Gemino Jeronimo das
Published: September 2022

Os seres que compõem a natureza precisam estar em harmonia, para juntos manterem o equilíbrio do planeta. Com o  objetivo de promover a Educação Ambiental por meio de ações ecológicas em uma Ecoescola, foi aplicado um formulário investigativo junto a 44 adultos. Os resultados obtidos por meio dos formulários aplicados demonstram que aquela comunidade é afetada pelos problemas ambientais existentes na área onde residem; ser o “lixo” o problema ambiental na área de moradia, e que os problemas ambientais existentes afetam sua vida. Também demonstram a importância da Educação Ambiental, no intuito de agregar valores acerca das ações ecológicas que podem ser melhoradas ou ampliadas na Ecoescola, que envolvam aquela comunidade e assim proporcionar um melhor entendimento sobre medidas e ações que podem ser tomadas para minimizar os problemas ambientais existentes naquela área, pois, a Educação Ambiental contribui para a sensibilização, a preservação, e a conservação ambiental do planeta.
Possibilidades terapêuticas para o tratamento da Leishmaniose Visceral Canina no Brasil: Revisão de literatura
Authors: Krolow Mariana Timm , Gomes Mariana Reis , Versteg Nielle , Waller Stefanie Bressan , Figueiredo Fabiano Borges , Cleff Marlete Brum , Dias Tábata Pereira
Published: September 2022

A Leishmaniose Visceral Canina (LVC) é considerada uma enfermidade endêmica em diversas regiões do Brasil, sendo foco de diversas políticas públicas em virtude de seu potencial zoonótico. A única medicação regulamentada pelo Ministério de Agricultura, Pecuária e Abastecimento (MAPA) no país, para o tratamento da enfermidade em animais, é a miltefosina. Desta forma, a busca por fármacos inovadores é necessária, os quais alguns já se encontram em fases de ensaios laboratoriais e outros têm sido indicados para uso na rotina clínica em outros países. Assim sendo, o objetivo do presente trabalho foi evidenciar as possibilidades terapêuticas contra a LVC, buscando ressaltar, principalmente, os novos fármacos frequentemente utilizados na rotina clínica, bem como aqueles que possuem potencial para se tornarem opções viáveis para a abordagem da LVC no Brasil.  Para a revisão, implementou-se uma busca sistemática manual nas principais bases de dados científicos, a partir da utilização de indexadores relacionados à temática no período de 1994 a 2022. Os resultados da busca sistemática revelaram que as opções terapêuticas potencialmente atuantes contra Leishmania infantum incluem marbofloxacina, beta-glucanas, imunomoduladores, além de óleos essenciais de plantas medicinais e seus compostos derivativos, sendo esses considerados candidatos promissores para o tratamento e controle da LVC.  Portanto, a partir dos dados reunidos, foi possível verificar que existem muitos estudos acerca da terapêutica da enfermidade e, que o entendimento pode ser decisivo no fornecimento de um bom atendimento ao animal doente, bem como na implementação de um planejamento medicamentoso adequado.