bluuebunny/crossref_metadata_2025 huggingface dataset:
DYSTHIROIDIE EN FRANCE : EVALUATION DES PRATIQUES DIAGNOSTIQUES DES MEDECINS GENERALISTES
Authors: GARNIER C , BASTIAN B , COLINEAUX H , CATHELAIN JB , ESVAN M , CHAPRON A , BIGOTTE PE , LE DOUARON P
Published: May 2024

Contexte. La Haute Autorité de santé a émis, en septembre 2021, des recommandations précisant les indications et non-indications de l’échographie thyroïdienne en cas de dysthyroïdie, afin d’améliorer la pertinence des soins, de réduire les dépenses et de favoriser la qualité du parcours de soins. Les pratiques des professionnels de soins primaires concernant les dysthyroïdies sont méconnues. Objectif. Évaluer les pratiques des professionnels à visée diagnostique (palpation et échographies thyroïdiennes) face à différentes situations clinico-biologiques de dysthyroïdies. Explorer les déterminants à la prescription d’échographies dans ces situations. Méthode. Étude descriptive transversale par questionnaire en ligne diffusé aux médecins généralistes de France métropolitaine par les conseils de l’Ordre et unions régionales des professionnels de santé. Comparaison aux recommandations des pratiques déclarées face à cinq situations cliniques fréquentes de dysthyroïdie. Résultats. Sur 506 médecins inclus, 453 (89,5 %) prescrivaient hors recommandation une échographie en cas de maladie de Basedow, 439 (86,8 %) en cas de thyroïdite d’Hashimoto. Plus de 90 % des répondants déclaraient palper la thyroïde pour chacune des situations, geste que 438 (86,6 %) trouvaient difficile. Cent cinquante (34,2 %) médecins déclaraient prescrire une échographie car ils doutaient de leur palpation thyroïdienne dans la thyroïdite d’Hashimoto. Les médecins déclarant être à l’aise avec la palpation prescrivaient en moyenne autant d’échographies que ceux qui n’étaient pas à l’aise (p = 0,26). Conclusion. Cette étude a permis pour la première fois une évaluation des pratiques professionnelles des médecins généralistes français dans la dysthyroïdie. Ces derniers semblent avoir des attitudes de prescription d’échographie non conformes aux recommandations, ce qui pourrait occasionner des surdiagnostics, coûteux et iatrogènes. La palpation thyroïdienne ne semble pas être un critère pertinent pour la réalisation d’une imagerie.
Perancangan Sistem Monitoring Energi Listrik Menggunakan NodeMCU ESP8266 dan PZEM-004T untuk Pengendalian Penggunaan Daya
Authors: Ahmad Wira , Widiatmoko Dekki , Kholid Fajar
Published: May 2024

Electricity is one of the essential needs for society today, serving as a primary economicresource. The use of electricity in household sectors reached 50.80% in 2020,contributing to the total electricity consumption in Indonesia each month. To raiseawareness about excessive electricity usage leading to inflated electricity bills, there is aneed for a remote monitoring and control device, based on the Internet of Things (IoT),specifically targeting electronic appliances that consume electricity.Addressing this issue, a research study titled "Design of Electricity Monitoring SystemUsing NodeMCU ESP8266 and PZEM-004T for Controlling Electricity Usage" wasconducted. The energy usage monitoring system is implemented in a terminal socketdevice capable of displaying power consumption through a module. Additionally, thisterminal socket can be connected to the internet, allowing users to view electricity usagedata on the ThingSpeak website. The necessary tools and materials for designing themonitoring and controlling system include a laptop, NodeMCU ESP8266 module,PZEM-004T sensor, relay (Rlay), OLED display, power terminal, plug (Stekker), andjumper cables.Based on testing using the blackbox method, the system has demonstrated effectivemonitoring and control of energy usage. It was observed that the power consumptionstated for an electronic device may differ from the actual power consumed. Thisdifference could be attributed to variations in the stated power consumption informationcompared to the actual power consumption.Keywords: households, NodeMCU ESP8266, PZEM-004T, IoT, electricity monitoring..
Flower Polination Algorithm Sebagai Optimalisasi LFC Pada Hybrid Pembangkit Wind-Diesel
Authors: Ali Machrus , Siswanto Agus , Baehaqi Mudofar
Published: May 2024

As input power, the amount of wind and wind speed greatly influences the wind power generation system. A combination of a wind-diesel power generation system is needed to obtain optimal power quality. A hybrid system is a controlled network of multiple renewable energy generators such as wind turbines, solar cells, micro-hydro, and so on. Gain settings that are not optimal and the time constant is small in Load Frequency Control (LFC), causing its ability to be weak (weak line). In practice, the wind-diesel system is controlled with a PID controller. Setting the gain value of the PID is still in the conventional method, so it is difficult to get the optimal value. In this research, a control design was implemented using the Smart Method to find the optimum value of the Proportional Integral Derivative (PID) based on the FPA (Flower Pollination Algorithm). For comparison, methods were used without control methods, conventional PID methods, PID Auto tuning methods, and FPA (Flower Pollination Algorithm) methods. Wind-diesel modeling uses transfer function diagrams of wind and diesel turbines. This study compares several uncontrolled methods and conventional PID, PID-Auto tuning, and PID-FPA. The results of the research that has been carried out show that the smallest undershoot is -1.187.10-04 for PID-FPA, the smallest overshot is 0 for PID-FPA, and the fastest settling time is 9.827 s for PID-FPA. So it can be concluded that PID-FPA is the best controller in this research. This research can later be continued using other artificial intelligence methods.
The Influence of Electronic Word of Mouth and Social Media Marketing On The Purchasing Decision of Small and Medium Enterprises (Case Study On Diyos Shoes Cleaning In Medan City)
Authors: Mulyadi Mardiyos Roy , Nurbaity Lubis Arlina , Gultom Parapat
Published: May 2024

This research aims to determine and analyze the influence of electronic word of mouth and social media marketing on purchasing decisions for small and medium enterprises (case study on Diyos Shoes Cleaning). This research is associative research and the type of data used is quantitative data. The population in this research is the unknown number of Diyos Shoes Cleaning customers in Medan City. The number of samples in this research was 170 customers. The sampling technique uses purposive sampling with the criteria of being 17 years of age and over, having social media, following the Diyos Shoes Cleaning social media account and domiciled in Medan City. The data analysis used is Multiple Linear Regression Analysis. The results of this research show that simultaneously electronic word of mouth and social media marketing have a significant influence on purchasing decisions for Diyos Shoes Cleaning services. Partially, electronic word of mouth and social media marketing have a positive and significant effect on purchasing decisions for Diyos Shoes Cleaning services.
Analisis Stretagi Pekerja Migran Indonesia dalam Menyikapi Kontrak Kerja
Authors: Santoso Rio
Published: May 2024

Indonesian Migrant Workers (PMI) Government to Government (G to G) process are faced with various challenges who work in South Korea through the South Korean, especially those related to work contract standards. PMI who are placed in workplaces in the manufacturing sector for E-9 visas and fishing for E-10 visas with a maximum work contract period of 4 years and 10 months during the first work contract period. PMI's standard work contract in South Korea through the Government to Government (G to G) program contains the rights and obligations of workers and employers. This research aims to provide an understanding of PMI's strategy in responding to employment contracts in South Korea. The subjects of this research were 48 Indonesian Migrant Workers in South Korea who had just worked in South Korea or who had worked by re-entry (entering work back into South Korea on a second contract). The type of data used is quantitative data, primary data collected through questionnaires with PMI who are working in South Korea, secondary data obtained through relevant literature studies. The data analysis technique uses qualitative descriptive analysis. The research results show that: 1) effective communication with other people, migrant workers need to have good interpersonal communication skills, both with colleagues and superiors, 2) the importance of migrant workers having knowledge about their rights, work regulations, working conditions in Korea South, 3) migrant workers need knowledge and skills to recognize and deal with discrimination by adapting according to local culture and work environment, 4) skills can include language, technical and social skills to improve job opportunities even better.
Features of the activities of the jury institute in the Volga region in the period from 1864 to 1917
Authors: Бойко Н.С. , Куликов А.В.
Published: May 2024

осмысление и адаптация исторического опыта помогают избежать ошибок и негативных тенденций, которые свойственны эволюционным процессам развития гражданского общества при восприятии и внедрении различных моделей государственного устройства в период функционирования судов присяжных с 1864 г. по 1917 г. на территории Поволжских регионов, где данные суды были введены в систему судопроизводства рассматриваемого периода.

understanding and adaptation of historical experience helps to avoid mistakes and negative trends that are characteristic of the evolutionary processes of development of civil society when perceiving and implementing various models of government during the functioning of jury courts from 1864 to 1917 in the Volga regions, where these courts were introduced into the legal system of the period under review.
Melee weapons and defensive weapons of the nomads of Central Asia in the early Modern period
Authors: Панасюк Н.В. , Пастухов Д.А.
Published: May 2024

статья посвящена изучению военного дела кочевников Центральной Азии в период раннего Нового времени. Целью работы является анализ отличительных особенностей комплекса вооружения кочевников в период раннего Нового времени. Задачами работы являются выявление характерных черт оружия ближнего боя и элементов защитной экипировки в исследуемый период. Анализируются вещественные, письменные и этнографические источники. Освещается вопрос типологизации клинкового, длиннодревкового, ударного и ударно рубящего оружия. Проводится анализ видов защитного вооружения, рассматриваются различные методы сборки панцирного доспеха, а также материалы изготовления подобной экипировки. Понимается вопрос боевых шлемов, наручей, поножей, набедренников и наплечников. Анализируются изменения в области применения как стационарных, так и ручных боевых щитов. Рассматриваются методы производства или приобретения кочевниками различных видов вооружения. Работа может стать основой или составной частью большого комплекса исследований в рамках изучения всего комплекса вооружения центральноазиатских кочевников на завершающем этапе своего самостоятельного развития. Также, на основании проведенного исследования возможна работа в области экспериментальной археологии, с созданием различных элементов вооружения и испытанием их тактико-технических характеристик.

the article is devoted to the study of the military affairs of the nomads of Central Asia in the early Modern period. The purpose of the work is to analyze the distinctive features of the nomad armament complex in the early Modern period. The objectives of the work are to identify the characteristic features of melee weapons and elements of protective equipment during the study period. The material, written and ethnographic sources are analyzed. The article highlights the issue of typologization of bladed, long-bladed, percussive and shock-chopping weapons. The analysis of types of protective weapons is carried out, various methods of assembling armored armor are considered, as well as materials for manufacturing such equipment. The issue of combat helmets, armbands, greaves, loincloths and shoulder pads is understood. The changes in the field of application of both stationary and manual combat shields are analyzed. The methods of production or acquisition of various types of weapons by nomads are considered. The work can become the basis or an integral part of a large complex of studies within the framework of studying the entire complex of weapons of Central Asian nomads at the final stage of their independent development. Also, based on the conducted research, it is possible to work in the field of experimental archaeology, with the creation of various elements of weapons and testing their tactical and technical characteristics.
The fight against misappropriation of socialist property, bribery and speculation in the early 1980s by the materials of the Smolensk region
Authors: Иванов А.М. , Купченко К.В. , Федоскин Н.Н. , Шерашенкова Е.А.
Published: May 2024

данная статья посвящена освещению реализации борьба с хищениями социалистической собственности, взяточничеством и спекуляцией в начале 1980-х годов по материалам Смоленской области. Авторы работы вводят в научный оборот архивные материалы из фондов Смоленского обкома партии в Государственном архиве новейшей истории Смоленской области (далее ГАНИСО). На основе архивных данных авторы выявляют просчеты и недостатки, существовавшие в советской системе, приводиться примеры хищений социалистической собственности. В статье делается вывод, что в начале 1980-х годов в регионе накапливались многочисленные негативные факты бесхозяйственности, безответственности руководства предприятий, ошибок в планировании и реализации плановых заданий, впоследствии приведших к системному кризису, не только экономику Смоленской области, но и всего СССР.

this article is devoted to the coverage of the implementation of the fight against misappropriation of socialist property, bribery and speculation in the early 1980s based on the materials of the Smolensk region. The authors of the work introduce archival materials from the funds of the Smolensk Regional Party Committee in the State Archive of Contemporary History of the Smolensk Region (hereinafter referred to as GANISO). On the basis of archival data, the authors identify the miscalculations and shortcomings that existed in the Soviet system, Examples of theft of socialist property are given. The article concludes that in the early 1980s, numerous negative facts of mismanagement, irresponsibility of enterprise management, mistakes in planning and implementation of planned tasks, which subsequently led to a systemic crisis, not only the economy of the Smolensk region, but also the entire USSR, were accumulating in the region.
“A look at the sky of the Second Rome from the Rome of the Third” (meteorology of Byzantium in miniatures of the Front Chronicle)
Authors: Деминцев М.С.
Published: May 2024

автор статьи обращается к миниатюрам Лицевого летописного свода XVI в. как к источнику по атмосферным и астрономическим феноменам Византии в период с IV по X век. Подчеркивается значимость визуальной информации, содержащейся в миниатюрах указанного источника для исследования метеорологии Византии. Лицевой летописный свод важен с точки зрения изучения вопросов, связанных с восприятием Византии и ее истории в Московском государстве. Опираясь на методы семиотики и системного анализа, автор рассматривает миниатюры в контексте единой иконографической системы. Из общего массива визуальной информации миниатюр, автор выделяет несколько групп метеорологических феноменов, таких как солнечные и лунные затмения, кометы, метеоры, грозы и др. В результате проведенного исследования выявлены реалистические черты в изображениях метеорологических феноменов. Несмотря на имеющиеся тенденции к натуралистичности, в целом изображения метеорологических феноменов на миниатюрах выполнены в рамках канона, доминировавшего в изобразительном искусстве Московской государства. Кроме того, автор приходит к выводу, что уровень исполнения иллюстраций метеорологических феноменов русскими миниатюристами, позволяет говорить развитии естественнонаучных представлений в Московском государстве.

the author of the article refers to the miniatures of the Front Chronicle of the XVI century as a source on atmospheric and astronomical phenomena of Byzantium in the period from IV to X century. The importance of the visual information contained in the miniatures of this source for the study of meteorology of Byzantium is emphasized. The facial chronicle is important from the point of view of studying issues related to the perception of Byzantium and its history in the Moscow state. Based on the methods of semiotics and system analysis, the author considers miniatures in the context of a single iconographic system. From the general array of visual information of the miniatures, the author identifies several groups of meteorological phenomena, such as solar and lunar eclipses, comets, meteors, thunderstorms, etc. As a result of the conducted research, realistic features in images of meteorological phenomena were revealed. Despite the existing trends towards naturalism, in general, the images of meteorological phenomena on miniatures are made within the framework of the canon that dominated the visual arts of the Moscow state. In addition, the author concludes that the level of execution of illustrations of meteorological phenomena by Russian miniaturists allows us to talk about the development of natural science concepts in the Moscow state.
Showcase: Emergency Education Response, Education Above All's collaborative projects for Ukraine
Authors: Lee Jamie , Voutilainen M. Mariah , Green Crystal
Published: May 2024

Conflicts, natural disasters, and epidemics derail the lives of children. Without access to education, they risk losing their futures. Education is consistently cited as top priority for parents and children in crises, yet it is often the first service lost and last restored during emergencies. Education in emergencies requires quick response and attention to the immediate needs of the learners in crisis situations. In this collaborative project, Education Above All’s Innovation Development (EAA’s ID) directorate brought together partners Positive Education Institute (PEI) and Think Equal to join efforts in providing emergency education support for Ukrainian refugees.
Citizen hydrospatial sciences - To csB or not to csB, that is the question!
Authors: Hains Denis , Keating Steven Geoffrey , Rathnayake Chandana , Obura Victoria , Sharma Shereen , Hall Stephen
Published: May 2024

Citizen science, where individuals and interested groups of people contribute to scientific research, has been growing significantly. In the hydrospatial realm, covering everything from the water's surface and column, to its depths, to its bottom and its sub-bottom composition and its coastal areas; citizen scientists collect valuable data. This note is using Citizen Hydrospatial Sciences as an overall introduction and context. The note really focuses and dives into the Crowdsourced Bathymetry (CSB) topic challenges and opportunities facing the global hydrographic community. Surprisingly, only about a third of the International Hydrographic Organization's (IHO) Member States (MS) and/or Hydrographic Offices (HOs) have responded to the IHO Secretariat's call for supporting the CSB initiative. Although this constitutes a great achievement and commitment, this raises questions: Why are not more HOs getting involved? Denis Hains discussed this in its Keynote address at the Hydro 2023 Conference in Genoa, Italy, sparking further discussion. This note follows up on Hains’ talk, looking more particularly into the CSB data quality and legal concerns worries some HOs seem to have. It is important to indicate, though, that while this note explores these issues, it does not offer legal advice.
Pendidikan Islam: Bagaimana Pengaruhnya dalam Membentuk Karakter Mahasiswa yang Bertanggung Jawab dalam Menegakkan Hukum di Kampus?
Authors: Damayanti Alif , Maulidina Annisa , Moniaga Friska Valentina , Munawaroh Siti Rahma , Suresman Edi
Published: May 2024

The aim of this research is to examine and analyze the influence of Islamic religious education on the formation of student character who is responsible for upholding the law in the campus environment. Quantitative methods are the type of method used in this research. The independent variable (X) in this research is Islamic religious education and the dependent variable (Y) in this research is the student's character in upholding the law. The population in this study were students from the Faculty of Economics and Business Education, Indonesian Education University, class 2022-2023 with a sample of 72 students. Data analysis was carried out using linear regression analysis techniques. Based on validity and reliability tests, the instruments used for data collection show that the instruments are valid and reliable. Based on the hypothesis test, it is known that the calculated t of 10.335 is greater than the t table of 1.66691 and the calculated F result of 106.805 is greater than the F table of 3.89, and the significance result of 0.000 is less than 0.05.  The results of this research show that there is a positive and significant influence of Islamic religious education on the character of students who are responsible for enforcing the law in the campus environment.
تأثير استخدام اللعبة اللغوية "الكلمات المتقاطعة" على استيعاب الطلاب القواعد الإملائية (بحث تجريبي في الفصل الثاني المتوسط بالمدرسة الإسلامية المتوسطة الحكومية ليما فولوه باتو بارا)
Authors: Sinaga Hana Khoirany , Zaky Ahmad , Tumanggor Ilham
Published: May 2024

Writing is one of the productive communication skills in the language. This is the process by which someone changes the language code from spoken language to written text. The writing skill has two divisions: calligraphy, dictation, and composition.  Dictation is one of the important subjects in teaching the Arabic language. Hence, dictation is the basis for success in writing skill. Teaching dictation looks at how to write correct Arabic grammar. Dictation is considered a person's ability to write letters in the Arabic language. Dictation is a basic learning skill in writing that requires a special method to master it. The method used is the quantitative method with an experimental method design with a post-test. The design for this research is the true experimental design with the type of posttest method (posttest only control group). The researcher takes a sample of forty-eight students from the second semester of middle school. This number is divided into two groups, group A and group B, and the researcher takes these two groups because group A is the experimental group and group B is the control group. From this, the researcher makes 24 students in the experimental class and 24 students in the control class. As for analyzing the data using a statistical method, SPSS 18, and the population size was 56 and 48 people were sampled. The result on the effect of the crossword language game is the reciprocal hypothesis, that is, the result in the t-test is 4.51 greater, while the result in the t-table is 02.01063.
Evaluasi Kinerja Guru untuk Meningkatkan Mutu Pembelajaran di SDN Lidah Wetan IV Surabaya
Authors: Salsabila Putti Erian , Aini Nushah , Lintang Rehan Puspa , Trihantoyo Syunu , Nuphanudin Nuphanudin
Published: May 2024

Teacher performance evaluation is a process of assessment and supervision carried out systematically to obtain real results and will be used as a reference for further performance development. Teacher performance evaluation is very important to determine the quality of a teacher in doing his job. By knowing the weaknesses or shortcomings of a teacher, the principal can plan a training program that is in accordance with the quality of the teacher. Good teacher quality is very important in the quality of learning, both to achieve learning goals at school and student activeness in the learning process. This article aims to analyze how to evaluate teacher performance at SDN Lidah Wetan IV Surabaya. The method used in this research is qualitative method. Data collection techniques in the research are observation and interview. The subjects in this study were principals, teachers, and students. The results showed that the Principal of SDN Lidah Wetan IV Surabaya is quite good in evaluating teacher performance, this is evidenced by the principal in providing guidance, supervision, and motivation to teachers so that teacher performance can experience good development.
Memahami Peran Komunikasi Orang Tua-Guru pada Motivasi Siswa SD
Authors: Ramadhani Ananda , Nisa Sahrun
Published: May 2024

The role of communication between parents and teachers in enhancing student motivation in elementary schools is crucial. Referring to various studies conducted by experts, it is found that strong and regular communication between parents and teachers has a positive impact on strengthening collaborative relationships, facilitating the exchange of relevant information, and helping to solve emerging problems. Additionally, a good partnership between parents and teachers can influence students' perceptions of learning and assist in better understanding the individual needs of students. Therefore, it is important for educators to recognize the significance of parent-teacher communication, overcome potential barriers, and build positive relationships with parents to support the optimal development of students in elementary schools.
Meningkatkan Kemampuan Literasi dan Berhitung bagi Siswa Kelas Rendah SDN Durung Bedug
Authors: Iffat Chanifatul , Maghfiroh Filzah Batrisyiyah , Haque Zanneta Arinil
Published: May 2024

The aim of this research is to find out how to improve literacy and numeracy skills for lower class students at SDN Durung Bedug. Then the results of the research we obtained are presented in the form of articles to fulfill the assignment for the Educational Evaluation course. This research was conducted at SDN Durung Bedug which is located at Jl. Durung Bedug, New Bedug, Lebo, District. Sidoarjo, Sidoarjo Regency, East Java 61223. This research uses qualitative methods by coming directly to the research location then observing interviews, namely questions and answers with the school, then we analyze the results of the research to produce articles. Researchers also use literature study methods, by collecting library data, reading and taking notes, and processing research materials. With the research we conducted, it can be concluded that reading or literacy and numeracy skills in the lower grades are very important and must be possessed by a student. Without literacy and numeracy skills, it will hinder students' progress in the learning process. Literacy and numeracy skills have a big impact on students forever. By having this ability, students can understand and absorb every word or explanation the teacher says in class and can understand every question they face, so that students will easily understand the questions and minimize misunderstandings in understanding and working on the questions. Literacy and numeracy skills can also hone students' abilities in thinking critically, making decisions, and understanding information from reading.
Pemetaan Kesesuaian Nilai Lahan dengan Zona Nilai Tanah di Kota Padang Panjang
Authors: Jannesman Hafiz , Ahyuni Ahyuni
Published: May 2024

This research aims: (1) To determine the distribution of land values based on the determining parameters of land values in Padang Panjang City. (2) To identify the Zona Nilai Tanah (ZNT) in Padang Panjang City. (3) To analyze the level of conformity between land values and Zona Nilai Tanah (ZNT) spatially in Padang Panjang City. The method used in this research is a weighted quantitative hierarchical method, which is then analyzed using overlay and classified with Equal Interval data classification. The research results show that land values in Padang Panjang City are dominated by the moderate category with an area of 853,28 ha or 36,83%, and in the Zona Nilai Tanah (ZNT), it is dominated by the low category with an area of 1.274,25 ha or 73,65% of the total area. The overlay results between the land value map and the classified Zona Nilai Tanah (ZNT) map produced a conformity level of only 20,32% with an area of 351,57 ha, and the non-conformity category reached 79.68% with an area of 1.378,53 ha.The dominant factor causing the discrepancy is due to the difference in spatial data distribution between land values and Zona Nilai Tanah (ZNT).
Using Interventional Pharmacoeconomic Clinical Trials and Outcomes-Based Contracts to Repurpose Generic Drugs with Cost-Savings
Authors: Kerdemelidis Savva
Published: May 2024

One of the greatest barriers to the repurposing of generic drugs is the lack of a financial model to recover the costs of clinical trials. Academics have acknowledged this “problem of new uses” for many years.[1] And so despite their great medical and cost-saving potential, repurposed generic drugs are referred to as “financial orphans” [2], “highly non-excludable therapies” [3], or “unmonopolisable therapies” [4], that are extremely unlikely to receive the funding needed for regulatory approval. One proposed solution to the problem of new uses is to restrict off-label use and allow reimbursement of the repurposed generic at a higher price for the new indication.[5] Another option is the increased public funding of clinical trials. However, this has been politically, legally and practically difficult to achieve.

A financially-innovative solution to the problem of new uses is to leverage the immediate and future cost savings of health insurers. In particular, the novel discipline of interventional pharmacoeconomics (IVPE) allows for self-funding clinical trials by comparing a low-cost intervention (such as a repurposed generic) to expensive standard of care.[6] The cost savings from patients taking the low-cost intervention in one arm can exceed the cost of the trial itself, even if it fails, which means there is no financial risk. However, an IVPE trial requires the substitution of the low-cost intervention for expensive standard of care, and may not be appropriate for all repurposing opportunities, especially where no expensive comparator intervention is available. For this latter situation, it is possible to use outcomes-based incentives similar to prizes called Pay-For-Success (PFS) contracts, Advance Market Commitments (AMC) [7], or Social Impact Bonds (SIBs).[8] Such “prize-like” incentives have been used to accelerate the development of Covid vaccines [9] and antibiotics [10], but not yet for repurposing generic drugs.

The IVPE concept has been called a ‘revolving research fund’ in Europe, where the cost-savings of clinical trials are used to fund additional research.[11] Similar cost-saving trials are also being funded by a consortium of health insurers in the Netherlands on a case-by-case basis.[12] It is hereby proposed that establishment of an IVPE + AMC fund by private or public health insurers can develop repurposed generic drugs, which can address the “financial toxicity” of new patented drugs while improving patient outcomes.[13] There are many known IVPE opportunities, for example, comparing repurposed generic IV ketamine to patented esketamine for treatment resistant depression [14] or off-label bevacizumab (Avastin) to ranibizumab (Lucentis) for macular degeneration.[15] There is an opportunity to discover and medically de-risk additional IVPE repurposing candidates for self-funding trials by conducting retrospective studies and meta-analyses of medical records and clinical data.
Upaya Peningkatan Hasil Belajar Matematika melalui Pendekatan TaRL: Penelitian Tindakan Kelas
Authors: Prastiwi Hangrainy , Amin Siti Maghfirotun , Prihastuti Haning , Muawanah Muawanah , Indrati Joeli
Published: May 2024

ABSTRAK
Banyak peserta didik tidak suka pelajaran matematika karena dianggap susah dan sulit, maka dari itu guru harus membuat pembelajaran yang berpihak kepada siswa dan sesuai dengan karakteristik peserta didik agar peserta didik menjadi menyukai pelajaran matematika.Salah satu upaya untuk membuat pembelajaran berpihak terhadap siswa dan membuat hasil belajar peserta didik maksimal yaitu dalah satunya menerapkan pendekatan yang sesuai dengan kemampuan awal siswa dengan menerapkan mengguankan pendekatan TaRL. Maka dari hal tersebut tujuan penelitian ini yaitu menarapkan pendekatan pembelajaran TaRL untuk meningktakan hasil belajara matematika kelas IIB SDN Margorejo VI Surabaya. Penelitian ini dilakukan dengan dua siklus yaitu dalam satu siklus dilakukan masing-masing dua tindakan pertemuan. Peneliti menerapkan model penelitian model Kemmis dan Mc. Taggart, karena alurnya sesuai dengan yang peneliti inginkan. Dari hasil penelitian yang dilakukan diketahui bahwa pembelajaran mateamtika satuan waktu melaui  pendekatan TaRL hasil aktivitas guru meningkat 7% dan aktivitas  peserta didik meningkat 6,5%. Dari hasil penelitian  diektahui yakni terdapat peningkatan hasil belajar peserta didik sebesar 52% setelah penerapan pendekatan TaRL.
ABSTRACT
Many students do not like mathematics lessons because they are considered difficult and difficult, therefore teachers must make learning that is pro-student and in accordance with the characteristics of students so that students will like mathematics lessons. One effort to make learning pro-students and produce results Maximum student learning is by applying an approach that is appropriate to the student's initial abilities by using the TaRL approach. Therefore, the aim of this research is to apply the TaRL learning approach to improve mathematics learning outcomes for class IIB SDN Margorejo VI Surabaya. This research was carried out in two cycles, namely in the first and second cycles there were 2 meeting actions each. Researchers use the Kemmis and Mc model. Taggart, because it is easy to understand and implement. From the results of the research conducted, it is known that learning mathematics in units of time using the TaRL approach results in teacher activity increasing by 7% and student activity increasing by 6.5%. From the research results, it is also known that student learning outcomes increased by 52% after implementing the TaRL approach.
Preparing for a Quantum Future: Strategies for Strengthening International Data Privacy in the Face of Evolving Technologies
Authors: Abdikhakimov Islombek
Published: May 2024

As quantum computing advances, the potential threat to data privacy intensifies, necessitating a proactive approach to strengthen international data protection measures. This article explores the current state of data privacy, the impact of quantum computing, and proposes strategies for addressing the challenges and opportunities presented by this evolving technology. Through a comprehensive literature review and expert interviews, we identify key areas for improvement and provide recommendations for policymakers, organizations, and individuals to enhance data privacy in the quantum era. The findings highlight the importance of developing quantum-resistant cryptography, adopting privacy-enhancing technologies, fostering international cooperation, and investing in research and development efforts to ensure the protection of sensitive data in the face of quantum computing.
Handbook for the Fifth Montevideo Programme on the Progressive Development and Implementation of Environmental Law
Authors:   United Nations Environment Programme
Published: May 2024

The Montevideo Programme V secretariat has developed this digital handbook that highlights the Programme’s objectives, activities and outcomes in order to raise awareness and enhance understanding of the Programme by Governments and relevant stakeholders. This will create a strong and recognizable brand for the Programme and serve as a guide that strengthens the role of Government officials and other users in the further development and implementation of its priority areas.
Analysis of English Lesson Plans of Junior High School Teachers in Bumiayu District
Authors: Maulia Bunga Putri , Dwinalida Khairunnisa
Published: May 2024

This study aims to find out the quality of lesson plans created by English teachers of Junior High Schools at Bumiayu Brebes Regency. The type of study is quantitative descriptive with documentation techniques. The instrument assessment in this study used an assessment sheet made with the 2013 curriculum standard by referring to Circular Letter Number 14 of 2019 concerning the Simplification of Lesson Plans, which the expert has validated. The results of this study is that the English lesson plans generally dominated in the “Below Average” category with 79%. It follows the results, which shows that the “Very Good” category is 0%, the “Good” category is 2.6%, the “Average” category is 18.4%, and the “Below Average” category is 79%. The data results are stated based on the facts according to the field, and there is no training or counselling on the preparation of good and correct lesson plans that government regulations have determined according to the 2013 curriculum. It needs to be the main focus that the competence of Junior High School English teachers at Bumiayu Brebes Regency has not fully mastered the writing of lesson plans according to the standard of writing lesson plans
The Use Of The Indonesian Language In International Contracts After The Circular Letter Of The Supreme Court Number 3 Of 2023 As Guidelines For The Implementation Of Duties For Courts
Authors: Anggraeni Yustina , Moh. Saleh Moh. Saleh
Published: May 2024

The use of the Indonesian language in memoranda of understanding and agreements with foreign parties is mandated as regulated in Law Number 24 of 2009 concerning the Flag, Language, State Institutions, and National Anthem as well as Presidential Regulation Number 63 of 2019 concerning the Use of the Indonesian Language. However, the provisions do not clearly stipulate the legal consequences if not adhered to, leading to the issuance of Supreme Court Circular Letter Number 3 of 2023 regarding the Implementation of Formulations from the Plenary Meeting of the Supreme Court Chamber in 2023 as Guidelines for the Implementation of Duties for Courts. This raises questions about the status of the Supreme Court Circular Letter within the National Legal System and the legal implications of the Supreme Court Circular Letter regarding the use of the Indonesian language in memoranda of understanding and agreements between foreign parties.
Deliberative Democracy Formation In Political Education: A Case Study On The National Democratic Party (Nasdem) Of DKI Jakarta
Authors: Sambojo Utomo Muhammad Shabri , Jatmiko Mochamad Iqbal
Published: May 2024

This study aims to analyze the formation of deliberative democracy in political education within the National Democratic Party (NasDem) of DKI Jakarta. By employing the concept of deliberative democracy, we argue that the NasDem Party of DKI Jakarta applies a democratic intersubjective dialogue process in decision-making regarding internal party political education. Although research on political education in general within political parties in Indonesia has been widely discussed, this paper complements previous studies by considering democratic inter-agent interactions and analyzing the discourse of deliberative democracy in political education within the NasDem Party of DKI Jakarta. Through qualitative exploration with descriptive case studies of two informants, field findings indicate that interactions in political education within the NasDem Party of DKI Jakarta are democratic in line with the party's ideological foundation, which guarantees internal democracy and promotes public democratization. Additionally, political parties also engage in empowering active members through participatory procedures and facilitate deliberative decisions in legitimizing internal political education from the village level to the provincial level. These findings contribute to an intra-party deliberative democracy model aimed at empowering members and offering a political public forum that prioritizes deliberation in influencing decisions.
Policy Analysis Regarding The Maintenance Of Religious Harmony And The Establishment Of Houses Of Worship (Implementatation Study of the Joint Regulation of Minister of Religion And Home Affair Minister Number 9/8 of 2006 in Cilegon City, Banten Province)
Authors: Rozikin Rozikin , Suradinata Ermaya , Mulyati Deti , Achmad Mansyur
Published: May 2024

Indonesia, as a large country in the Asian region, is characterized by thousands of islands, a population of hundreds of millions of people, and various ethnicities, races and religions. However, behind this diversity it can also be a trigger for conflict, both internal and external. One aspect that is often highlighted is the role of religion in conflicts between religious communities. Joint Regulation of the Minister of Religion and the Minister of Home Affairs Number 9/8 of 2006 concerning the Establishment of Houses of Worship was established to regulate procedures for building places of worship, including construction, maintenance and management. However, the implementation of these regulations in the field often faces various challenges and obstacles. The research reviews the implementation of these regulations in the City of Cilegon, Banten. The review presented relate to the licensing context, the concept of religious harmony, and the concept of establishing places of worship. The method used is qualitative research with literature study as a data acquisition technique. The research results show that the implementation of the Joint Regulation of the Minister of Religion and the Minister of Home Affairs Number 9/8 of 2006 concerning the Establishment of Houses of Worship in Cilegon City has not been fully effective. Socialization efforts, improving regulations, and enforcing government neutrality are the main keys in increasing the effectiveness of implementing these regulations.
Prevención secundaria de restenosis Intrastent: Transición de cuidados de enfermería al alta hospitalaria
Authors: Pascual Andréu Juan Carlos
Published: May 2024

A pesar de los avances en el diseño de stent para el tratamiento percutáneo de la enfermedad coronarias severa, aún no se ha logrado la combinación de fármacos, plataformas y recubrimientos que permitan eliminar por completo la reestenosis del stent a largo plazo, precisando un tratamiento de doble antiagregante plaquetario como medida preventiva en la aparición de un nuevo evento coronario, que no es tan infrecuente, ni tan benigno.
Junto con el desarrollo de medidas como elección del stent, emplear técnicas minuciosas adaptadas al tipo de lesión y tratamiento antitrombótico ajustado a las circunstancias de cada paciente para evitar situaciones indeseables, es necesario identificar a los pacientes coronarios más vulnerables y realizar acciones dirigidas a un cambio de estilo de vida y una buena adherencia terapéutica, con el fin de reducir factores de riesgos cardiovasculares y promover bienestar. Para ello, la intervención de enfermería desde la atención secundaria es fundamental.

Palabras clave: angioplastia, reestenosis coronaria, atención secundaria de salud, factores de riesgo de enfermedad cardiaca, cumplimiento y adherencia al tratamiento.
أثر إعادة الهيكلة التكنولوجية على القدرة التنافسية للموانئ السعودية (دراسة حالة: ميناء الملك عبد العزيز بالدمام)
Authors: الصهيبي سعود بن هذال , إبراهيم محمد علي , هلال هشام
Published: May 2024

المستخلص تعتبر الموانئ من أهم العناصر اللوجستية في الاقتصاد العالمي، حيث تمثل نقطة تلاقٍ حاسمة لنقل البضائع والتجارة الدولية. ومع تزايد حجم التجارة العالمية والمتطلبات المتزايدة للفعالية والسرعة في نقل البضائع، أصبح من الضروري أن نولي اهتماماً كبيراً لإعادة هيكلة التكنولوجية في الموانئ. تسهم إعادة الهيكلة التكنولوجية في الموانئ في تحقيق أهداف الاستدامة البيئية. تواجه الموانئ السعودية وخاصة ميناء الملك عبدالعزيز بالدمام ضعف في مواكبة التطور التكنولوجي بنظم المعلومات والاتصالات بالرغم من توافر الإمكانيات المالية والبشرية. ومن المقابلات الشخصية التي قام بها الباحث تبين وجود انخفاض في كفاءة العمليات بميناء الملك عبدالعزيز. تهدف الدراسة لتوضيح أثر إعادة هيكلة الموانئ ودورها الفعال في زيادة كفاءة العمليات بالموانئ السعودية لتصبح موانئ ذكية بالتطبيق على ميناء الملك عبدالعزيز بالدمام؛ وبالتالي زيادة قدرة الميناء التنافسية. اتبع الباحث المنهج الوصفي، حيث تم استخدام التحليل الرباعي SWOT لمعرفة نقاط القوة والضعف وكذلك الفرص والتهديدات لمعرفة أثر إعادة الهيكلة التكنولوجية بميناء الملك عبدالعزيز بالدمام.
Analyzing The Cognitive Experiences Of Individuals Linked To Regular Exercise At The Gym: An Interpretative Phenomenological Analysis (IPA)
Authors: Mahmood Sarah
Published: May 2024

Objective: As to date, little has been done to explore and understand the cognitive experiences of individuals with regular exercise at gyms in Pakistan through an in-depth qualitative analysis, therefore the study aimed to probe the cognitive experiences of the ones who had been into the practice of regular exercise and workouts at the gym.
Method: The participants i.e., males (N=3) and females (N =5), having 6 months of persistent exercising were approached from Shapes Health Studio (Fitness center/ gym), Multan, Pakistan. The age ranges of the recruited participants were from 25 to 40 years. Semi-structured interviews were conducted and the data were analyzed through an interpre[1]tative phenomenological analysis (IPA) to interpret common patterns focusing on each individual’s experiences thoroughly. The Verbatim of each participant was transcribed to generate the emergent interpretative themes which were categorized into sub-ordinate themes and further into super-ordinate themes.
Results: Four super-ordinate themes emerged: (1) influence of social media and social comparison, (2) appearance vs. expectations of body image, (3) mindfulness and improved quality of life, and (4) management of physical and psychological ailments.
Conclusion: Movement gives life as it has been revealed from the super-ordinate themes that mindfulness, improved quality of life, and management of ailments like obesity reduce body appearance comparison pressures. Furthermore, psychological ailments such as depression and anxiety are also managed well when the social media influences of having a perfect body are reduced through regular exercise. It can be hoped that the current study will help raise certain persuasion as well as awareness among the population to maintain regularity in their exercises at the gym to adapt a socially active and healthy lifestyle.
Follow Me to Unregulated Waters!
Authors: Holznagel Daniel
Published: May 2024

In this article, I will demonstrate how some major platforms are failing to ​properly ​implement the Digital Service Act's (DSA) rules on notice and action mechanisms. In my view, many platforms are ​unduly ​nudging potential notice-senders to submit weak, largely unregulated Community Standards flags. At the same time, platforms are actively deterring users from submitting (strong) notices regulated under the DSA.
Legal Aspects In Handling Money Laundering Cases In Indonesia
Authors: Riswanto Riswanto , Akbar Rachmatullah Muhammad , Rahman Alip , Dikrurahman Diky
Published: May 2024

Money laundering poses a serious threat to the integrity of the financial system and the stability of society, prompting the need for effective handling from all parties involved. This research discusses the legal aspects of handling money laundering cases in Indonesia. Using a descriptive-analytical qualitative approach, this study analyses the existing legal framework, its implementation in law enforcement practice, and the challenges faced by law enforcement officials in handling money laundering cases. Data was collected through literature study and analysis of money laundering cases that have been decided by the court. The results show that although Law No. 8/2010 has provided a strong legal foundation, there are still challenges in its implementation including limited resources, inter-agency coordination, and the development of increasingly sophisticated money laundering methods. Based on these findings, this research presents policy recommendations to strengthen law enforcement in handling money laundering offences in Indonesia.