bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of contributing factors of end stage renal failure for
Authors: Atiyah Hussein Hadi
Published: April 2023

Objectives: The study aimed to assess contributing factors of end stage renal failure for adult patients and to identify relationship between contributing factors with demographic characteristics.
Methodology: A descriptive study was carried out of Al-Shahid Ghazi Hariri Teaching Hospital, Al-Yarmook teaching hospital, Al-Karama teaching hospital, and Baghdad teaching hospital for the period of 22\2\2012 to 25\6\2012. Non-probability, purposive sample of (60) adult patients with end stage renal failure. Questionnaire form was constructed for the purpose of the study. It consisted of two parts:
1. Demographic data form (age, gender, marital status, educational level, resident, and occupation.
2. Contributing factors for end stage renal failure.
Data were collected through the application of the questionnaire and interview technique. Validity of questionnaire was response through panel of (10) experts. Test- Retest reliability was determined through a computation of Pearson Correlations for contributing factors of end stage renal failure (r=0.86). Data were analyzed through descriptive statistical approach (frequency and percentage) and inferential approach (mean of score and Pearson correlation coefficient).
Results: The finding of the study shows that the of age group were more than 46 years old and they are married with no read and write in level of education and they are living in urban resident.
Conclusions: The findings of the study sample indicated that the most common contributing factors were (diabetic nephropathy, uncontrolled hypertension, drug toxicity, smoking, and renal diseases) and there is strong positive relationship between age with poly arthritis and strong positive relationship between smoking's with resident, and there is strong negative relationship between occupations with kidney surgery
Recommendations: The study recommended that to providing centers for end stage renal failure under treatment for giving various services to help patients with good life in home and community.
Assessment of Stressful Life Events of Adult Patients with Ischemic Heart Disease in Baghdad City
Authors: Jaddoue Batool Amin , Al-Jubouri Mohammed Baqer Abbas Jaffar
Published: April 2023

Objectives: 1-To find out the relationship between stressful life events and socio-demographical characteristics (age, gender, marital status, and socioeconomic status) of adult patients with ischemic heart disease. 2-To assess the stressful life events of adult patients with ischemic heart disease (IHD) in Baghdad city.
Methodology: A descriptive study was carried out at three cardiac hospitals (Ebn-Alnafis, Ebn-Albitar, and Iraqi center for heart diseases). Starting in 15 of December 2011 to 4 of July 2012. A non-probability (purposive) sample of 180 patients that diagnosed with IHD who were admitting to medical or surgical ward of the above listed hospital were selected according to the criteria of the study sample. A questionnaire was adopted and developed in the social readjustment rating scale of Holms and Rahe (1967) and consist of (67) items. The content validity of the instrument was established through penal of (34) experts. Reliability of the stressful life events was determined by test-retest method which was estimated as average (r=0.916). Data was gathered by interview technique using the questionnaire format and data was analyzed by application of descriptive and inferential statistical methods.
Results: The results reveal that the majorities of study group were (60-69) years old, married, illiterate, and low socioeconomic status. The result indicated that the stressful life events play importance role in occurrence of IHD.
Conclusion: The majority of the IHD patients are male, married and illiterates. There is a highly significant relationship at p<0.01 between stressful life events and occurrence of IHD in adults.
Recommendations: increase the individual awareness about stress management, maintain supporting therapies, training efficient confrontation strategies for stressful factors, prediction the stressful life events, coping strategies, and adaptation to its, relaxation technique, improving individual's social support systems through group therapy, family therapy, and training communication skills can reduces the effects of stressful life events.
Thevenard Disease: Rare Association of 3 Cases in the Same Family (3 Sisters)
Authors: Abakka Mehdi , Ouagari Hamza El , Mekkaoui Jalal , Bouffetal Moncef , Bassir Rida Allah , Kharmaze Mohamed , Lamrani Moulay Omar , Berrada Mohamed Saleh
Published: April 2023

Thevenard's disease is a rare familial ulceromutilative acropathy, responsible for sensory peripheral neuropathy associated with dysautonomous syndrome. The delay in diagnosis and major comorbidities make this condition disabling. We report here a case of 3 sisters, with a history of parental consanguinity, received in Orthopedic and Traumatology Department for the management of a sensitive polyneuropathy, associated with pressure ulcers and ulcers arthropathies of the feet. Functionally, walking was possible without dodging lameness. The electromyogram was in favor of a sensory polyneuropathy of the four limbs. An artisan shoe footfeeding shoe has been proposed, in the face of delayed healing of the wound, associated with local care and sensorimotor rehabilitation. Thévenard's Disease is a rare nosological entity that requires multidisciplinary management.
Severe Malaria in Children Aged 6 to 59 Months in the Paediatric Ward of the Commune II Health Centre in Bamako
Authors: Keita Chaka , BA Kadiatou, , Niare Boubacar , Samake Zoumana , Sylla Fatoumata , Ouonogo Salia , Toure Sidi , Poma Hachimi , Diarra Samou , Coulibaly Hawa , Ouattara Kassim , Traore Bakary Abou
Published: April 2023

Introduction: The aim of our work was to study the epidemiological, clinical, paraclinical and therapeutic aspects of severe malaria in children hospitalized in the pediatric ward of the CSRéf commune II of the district of Bamako in Mali. Materials and methods: We conducted a 12-month prospective study from January to December 2017. It took place in the paediatric service of the CSRéf of the commune II of the district of Bamako. Results: The study involved 70 children hospitalised out of 418 in the paediatric ward. The prevalence of severe malaria was 16.7%. The age group of children aged 36-59 months was the most affected with 58.6% with a sex ratio of 1.12 in favour of boys. The reasons for consultation were dominated by fever (43%). The neurological form was the most frequent with 71.4% followed by the anaemic form with 21.4%. Injectable artesunate waś used as first line in 110 patients or 87%. The average duration of hospitalisation was 3.8 days. The evolution waś favourable 97% of patients and 3% death. Conclusion: Malaria remains a public health problem due to its frequency and severity in children.
Studi literatur: pemanfaatan teknologi biogas dari limbah organik di Indonesia
Authors: Fauziah Lulu Hani , Hidayatullah Ahmad Fauzan
Published: April 2023

Kebutuhan sumber daya energi semakin meningkat tiap tahunnya, sementara cadangan sumber energi fosil semakin berkurang dan akan habis pada masanya seperti batu bara, minyak bumi dan gas alam. Kontribusi dari hasil pembakaran minyak bumi dan gas alam menimbulkan emisi yang dapat mencemari bumi. Biogas merupakan energi terbarukan (renewable), ramah lingkungan dan memiliki peluang untuk dikembangkan sebagai energi alternatif yang mulai diperhitungkan. Dalam hal ini pemerintah berupaya dalam pengembangan energi terbarukan di seluruh Indonesia yang tertuang dalam PP Nomor 79 Tahun 2014 tentang Kebijakan Energi Nasional. Penelitian kualitatif ini bertujuan untuk mengetahui pemanfaatan biogas di Indonesia berdasarkan berbagai penelitian di beberapa daerah di Indonesia dengan meninjau pada studi sebelumnya untuk memberikan penjelasan tambahan tentang hambatan dan solusi pengembangan biogas di Indonesia
Evaluasi program penyediaan air minum dan sanitasi berbasis masyarakat (PAMSIMAS): studi di Kabupaten Temanggung
Authors: Puspita Dhestiane Sherly , Kawuryan Istiarsi Saptuti Sri , Handayani Widhi
Published: April 2023

Peningkatan jumlah penduduk berdampak pada alih fungsi lahan yang bermuara pada mencuatnya berbagai isu lingkungan, termasuk isu ketersediaan air bersih untuk memenuhi kebutuhan air bersih masyarakat. Penyediaan Air Minum dan Sanitasi Berbasis Masyarakat (PAMSIMAS) merupakan salah satu program pemerintah yang diupayakan untuk memenuhi kebutuhan air bersih dan sanitasi masyarakat. Meskipun masih ada kendala dalam pelaksanaannya, program ini telah menunjukkan manfaat dan dampak positif di berbagai daerah. Penelitian ini dilakukan untuk menjelaskan capaian program PAMSIMAS yang ada di Kabupaten Temanggung sebagai upaya pemerintah untuk meningkatkan kesejahteraan masyarakat Kabupaten Temanggung. Studi ini merupakan studi kuantitatif menggunakan data sekunder lalu dianalisis secara deskriptif. Hasil studi menunjukkan bahwa realisasi PAMSIMAS di Kabupaten Temanggung untuk air minum dinilai baik, yang terendah sekitar 75%, bahkan ada capaian yang melebihi target 100%. Realisasi PAMSIMAS masih fluktuatif, tiga kecamatan yang realisasi sanitasinya rendah yaitu Kecamatan Bansari (27,13%), Kecamatan Wonoboyo (8,00%) dan Kecamatan Tretep (6,00%). Faktor yang dapat mempengaruhi tingkat sanitasi tersebut adalah rendahnya tingkat ekonomi masyarakat, norma sosial yang lemah, dan modal sosial yang lemah. Studi lebih lanjut diperlukan untuk mengidentifikasi faktor penyebab rendahnya realisasi sanitasi di kecamatan tersebut sehingga dapat ditemukan solusinya
ANALYSIS OF RISK MANAGEMENT IN TERRITORIAL PLANNING IN AREAS SUSCEPTIBLE TO SLOW FLOODING. CASE STUDY RURAL SETTLEMENT “EL PLAYÓN” BAJO SINÚ (CÓRDOBA, COLOMBIA).
Authors:   Departamento de Ingeniería Ambiental Facultad de Ingenierías, Universidad de Córdoba Carrera 6, No. 76-103 Montería, Colombia, CÁRDENAS DE LA OSSA Jorge Edwin , FLÓREZYEPES Gloria Yaneth ,   Univerdidad Católica de Manizales – Grupo de Investigación GIDTA AV Santander, Cra 23 No 60-63 170003, Colombia, HERNÁNDEZ GARCÍA Diego ,   Universidad de Manizales, Cra. 9a # 19-03, 170001, Colombia
Published: April 2023

As a result of this research, it is proposed the incorporation of risk management as an environmental determinant in flood areas of the lower Sinú River basin for territorial planning. This was carried out through the analysis of the total flood risk, determining the threat and vulnerability of the target community, likewise, the risk drivers were identified under approaches of the integral analysis of holistic and systemic risk using a PAR model through which it is established the underlying reason, the dynamic relationship of the environment, the unsafe conditions of geography, and the socio-economic characterization of the community. In this way, it was not only obtained the analysis of the areas affected by the floods by identifying the causes and establishing a level of risk tolerance, but also the risk factors with their effects in the study area. This highlighted the importance of developing immediate and priority activities in the study area
ART EDUCATION IN UKRAINE IN EARLY 20TH CENTURY: EDUCATIONAL TECHNIQUES FOR NEW FORMATION ARTISTS
Authors:   ", PANYOK Tetyana Volodymyrivna ,   H. S. Skovoroda Kharkiv National Pedagogical University – Art Critic, Doctor of Pedagogical Science, Associate Professor. Head of Fine Arts Department"
Published: April 2023

The development of artistic education was carried out on the basis of Ukrainian culture and art, the personal significance of the traditions of art for students’ art and the artistic and pedagogical approaches of teachers. The training was based on the national and cultural consciousness of the students, the complex system of artistic training of the specialist was applied, the main principles of which were systematicity, consistency, structure, clear definition of the artistic purpose, connection with social life, development of creative individuality. Following the study of the art education historic experience, the paper confirms the significance and specifics of pedagogical approaches of the 20th century art teachers (М. Boichuk, V. Krychevsky, F. Krychevsky, H. Narbut), whose figures made up a bright and unique page in the modern Ukrainian art. The essential problems covered in the paper also include the analysis of historical and philosophical issues related to the development of higher art education.
ELEMENTS OF ARCHAIC MUSIC REFLECTED IN PETROGLYPHS AS A PHENOMENON OF CULTURAL HERITAGE, THE ORIGINAL SOURCE OF MATERIAL AND SPIRITUAL CULTURE
Authors:   Department of Music Education and Management, Kurmangazy Kazakh National Conservatory, Almaty, Republic of Kazakhstan, Аlmaty, 86 Abylai Khan Av., 50000, JANSEITOVA Svetlana , SULEYEVA Gulzhan ,   "Department of Music Education and Management, Kurmangazy Kazakh National Conservatory, Almaty, Republic of Kazakhstan, Аlmaty, 86 Abylai Khan Av., 50000", KURMANAEV Ermek ,   "Department of String Instruments, Kazakh National University of Arts, Astana, Republic of Kazakhstan, Tauelsyzdyk Avenue 50. Astana, 010000, Kazakhstan", RAUANDINA Sholpan ,   "Department of Folk Music, Kurmangazy Kazakh National Conservatory, Almaty, Republic of Kazakhstan, Ablayhan Avenue 86. Almaty, 50000, Kazakhstan", KOSANOVA Aigul ,   "Faculty of Traditional Musical Art, Kazakh National University of Arts, Astana, Republic of Kazakhstan, Tauelsyzdyk Avenue 50. Astana, 010000, Kazakhstan", ISKAKOV Bilal ,   " Department of Folk Music, Kurmangazy Kazakh National Conservatory, Almaty, Republic of Kazakhstan, Ablayhan Avenue 86. Almaty, 50000, Kazakhstan"
Published: April 2023

This article examines the process of forming a culture, the main characteristics of the emotional and spiritual attitude to the world, and the transition of emotions into the artistic and sensual imagery sphere. The necessity of researching petroglyphs, as the earliest sign systems, was revealed and substantiated; they reflect the initial stage of the formation of ancient art. For the first time, the model of the ancient ritual ceremonies was directly related to the religious beliefs found in the petroglyphs, with their semantic filling, which allowed to reveal the cosmogonic functions of ritual melodies in the process of perception of the world.
Education Influence in Human Resource Development
Authors: - Sunil Bhosale , - Dipak Shinde
Published: April 2023

In India, mainstream of population that is almost 64% is between the ages of 15 and 64 and nearly 31% is under 14 years of age. So MHRD focuses on the education of children, youth, skill and technical development of human resource. Education is basic human right and also a social capital. In the age of globalization, the importance of education is increasing day by day. Hence the government of India increase educational spending but that is not sufficient so government should spend much on education. During 1950-51 to 2019-2020 the number of Universities, College, student’s enrolments increased, moreover in the same period India’s Male/Female literacy rates have been increasing trend. Education influence in human resource development analyzed in this paper.
Capital Punishment and its Relevancy in Modern Indian Society
Authors: - Navdeep Kadian
Published: April 2023

Punishments are meant to uphold both law and order in the society and the capital punishment is regarded to be the severe most of them. Since the beginning of time, it has created a long history as a form of punishment. There are different techniques used for execution purposes in various nations. But the defenses against use of capital punishment have remained unchanged over time. It is considered by many that the capital punishment is one of the major reasons for violating the morality of the society and it also motivates retaliation. This is because of which many nations have abolished the concept of capital punishment, while some have done so only to bring it in use in case of certain events of extraordinary cases such as war crimes and so on. Both the UNGA as well as ICJ oppose the application of capital punishment. And even though many nations have abolished this concept, yet the countries like India, China, Pakistan and United States still practice it. In case of India, it is only in the “rarest of rare” events wherein the collective conscience of the community get shocked by the heinous crime conducted by the offender, that the capital punishment method is used. While the main objective of the execution of capital punishment is to satisfy the society’s feeling towards the hatred for crime, it should rather be curtailed as death penalty is not surety to vanish crime from the society. Even a single mistake through admission of facts may lead to the death of an innocent. Rehabilitation of an accused must be the main purpose rather than his/her death and focus must not be to eliminate a criminal, but to eliminate the crime.
Isaac Sharara’s Law of Proportional Value Added Tax Calculation in a Multi-currency economy. A case for Zimbabwe 2023
Authors: - Isaac Tsivai Sharara
Published: April 2023

This paper has a cardinal goal of suggesting a way or method to calculate Value added tax (VAT) in a multi-currency economy where the VAT must be collected and remitted in the currency of tender. This paper notes that a good VAT system must not affect the choices of the consumer in any way and also that, each taxpayer must be allowed to contribute to state tax collections in any of the officially allowed currencies in that economy. In this paper, proportions are used to calculate the contribution per currency within a single transaction involving a single standard rated product or service.
An Experimental Study on Stabilization of Soil by using Shredded Rubber Tyre
Authors: - S.D. Farhana Tabasum , - M. Laharipriya , - V. Saranya , - Y. Jyothsna , - D. Dharani , - M. Vijaya Lakshmi
Published: April 2023

Soil properties play very important role in construction. Sometime the properties of soil are not favorable for construction, and we used some method to improve properties of soil called soil stabilization. Improvement of load bearing capacity of the soil may be undertaken by a variety of ground improvement techniques. In this project we are using shredded rubber tyres to improve properties of soil. With ongoing rise in use of motor vehicles hundreds of millions of Tyres discarded each year throughout the world. Use of tyres in geotechnical engineering for improvement of bearing capacity of black cotton soil has received great attention in recent times. Shredded rubber tyres with different percentages (4%, 6%, 8%, 10%) of tyres by weight of soil sample for the experiment work. The investigation has been focused on the strength behavior of soil reinforced with randomly included shredded rubber fiber. The main objective is to increase the strength or stability of soil and to reduce the construction cost by using local available materials. The low strength and high compressible soft soils were found to improve by addition of shredded rubber. The samples were subjected to California bearing ratio and standard proctor test.
Production of Home-made Wine from Citrus Citrullus Lanatus Linn and Prunus Domestica Linn
Authors: - Devanshi Kasabwala , - Vaishnavi V. More
Published: April 2023

The present research aims to provide with relevant information regarding the preparation of home-brewed wine. Fruit wines bring in a potential for a lot of innovation, hence, seasonal fruits were used for the purpose of the present research.
Development of Analytical Technique for Dichlofenac Sodium and Ibuprofen Utilizing UV Visible Spectroscopy and AUC Method
Authors: - Ankit C. Rathod , - Ankush R. Dudhe , - Krushna H. Gajare
Published: April 2023

The purpose of this work was to create an analytical method combining UV visible spectroscopy and the AUC method for the simultaneous determination of diclofenac sodium and ibuprofen in their combination dosage form. The medications’ UV spectra were captured between 200 and 400 nm, and the calibration curves were built using AUC values for diclofenac sodium and ibuprofen at 274 nm and 222 nm, respectively. The developed method’s linearity, precision, accuracy, limit of detection, and limit of quantification were all validated in accordance with ICH recommendations. The findings demonstrated that the approach was linear, exact, accurate, and sensitive for the measurement of ibuprofen and diclofenac sodium. Without any excipient interference, the suggested approach was effectively used to determine the two medicines in their combination dose form. The created approach is straightforward, accurate, and cost-effective, and it may be utilised for regular analysis of ibuprofen and diclofenac sodium in their combination dose form.
বাংলা রঙ্গমঞ্চের দেড়শ বছর
Authors: - Subhanil Joardar
Published: April 2023

আদিমকাল থেকে মানুষ তার কর্মকাণ্ডকে প্রকাশ করার অদম্য প্রচেষ্টা চালিয়ে যাচ্ছে। পশু শিকার - কৃষিকাজ - নৃত্য - গীত - লিখন - পূজার্চনা - জীবনশৈলি - পরিবার ও রাষ্ট্র কলহ প্রভৃতি নানাবিষয়ে এর প্রকাশ যে আদিমকাল থেকেই হয়ে এসেছে, তার প্রমাণ আমরা পাই গুহাচিত্র , প্রত্নতাত্ত্বিক আবিষ্কার, স্থাপত্য প্রভৃতির মধ্যে দিয়ে। মানুষের উদ্ভাবনী শক্তি এখানেই সীমাবদ্ধ না থেকে সচেষ্ট হয় অভিনয়ের মাধ্যমে তার সকল কর্মকাণ্ডকে কি ভাবে সকলের সামনে মেলে ধরা যায়। এরই ফলশ্রুতিতে সৃষ্টি হয় নাট্যসাহিত্য তথা নাটক। আর এই নাটকের অভিনয়ের জন্য প্রয়োজন হয় নাট্যমঞ্চ তথা রঙ্গমঞ্চের। তাই এই সীমিত প্রতিবেদনে বিগত দেড়শ বছরের ( ১৮৭২- ২০২২ ) বাংলা রঙ্গমঞ্চের সংক্ষিপ্ত পর্যালোচন করার চেষ্টা হয়েছে মাত্র।
Digitale Medien in der schweizerischen Lehrerinnen- und Lehrerbildung: Hintergründe, Ansätze und Perspektiven
Authors: Petko Dominik , Döbeli Honegger Beat
Published: April 2023

Der Artikel gibt einen Überblick über die Bedingungen erfolgreicher Medien­integration in Schulen und den diesbezüglichen Beitrag der Lehrerinnen- und Lehrerbildung. Für die Nutzung digitaler Medien in Schulen ist neben dem Aufbau und dem Betrieb einer angemessenen technischen Infrastruktur vor allem die Entwicklung der diesbezüglichen Kompetenzen und Überzeugungen aufseiten der Lehrpersonen entscheidend. Für deren Aus- und Weiterbildung liegt die wichtigste Herausforderung aus heutiger Sicht in der Vermittlung eines «technological pedagogical content knowledge». Der Beitrag beschreibt und beurteilt auf der Grundlage dieser theoretischen Überlegungen die bisherigen Entwicklungen in der Schweiz und die aktuellen Herausforderungen für pädagogische Hochschulen.
Desain dan Simulasi Konverter Tiga Fasa AC – DC pada Pico Hydro
Authors: Priyanto Yun Tonce Kusuma , Matarru Andre Amba , Dewanto Muhammad Ridho , Wahyudi Rizky
Published: April 2023

Pico hydropower plant is a generator engaged in the field of renewable energy, in general, the power system uses a 3-phase synchronous generator with AC voltage, in its development it can be used as a converter, by converting AC voltage to DC voltage. One of the uses of DC voltage is as so that it can be used as a battery charger or battery discharger. An AC-DC converter, also known as a rectifier, is a device for converting alternating current (AC) to direct current (DC). In general, many technologies in the industrial world utilize converters. In this paper, a simulation design of an AC-DC converter system will be made with a 230 Volt AC input with a DC voltage output. The manufacture of the converter is carried out with different gate values on the thyristors which are simulated using Simulink in MATLAB. The results of this study are in the form of analysis and mathematical calculations of the output of the AC-DC converter where from the simulation results that AC voltage can be converted to DC voltage with the working principle of the thyristor, thus the converter output results can be used in battery chargers and battery dischargers
Phytochemical screening of Psidium guajava and Carica papaya leaves aqueous extracts cultivated in Greece and their potential as health boosters
Authors: Ntakoulas Dimitrios D. , Pasias Ioannis N. , Raptopoulou Kalomoira G. , Dimitriou Georgios , Proestos Charalampos
Published: April 2023

Aim: The scope of the present study was to investigate the phytochemical profile of Psidium guajava and Carica papaya leaves aqueous extracts, from plants cultivated on Crete island in Greece.
Methods: Total phenolic content (TPC) in the aqueous extracts was determined spectrometrically using the Folin-Ciocalteu (F-C) assay. The identification and quantification of different phenolic compounds in the aqueous extracts were conducted using reversed-phase high-performance liquid chromatography (RP-HPLC) analysis. Different metals were also determined (K, Fe, Zn, Ca, Mg, Pb, and Cd) to investigate the potential health claims or hazards in the water extractable infusion using inductively coupled plasma mass spectrometry (ICP-MS) method.
Results: TPC in the aqueous extracts was found to be 28.0 g gallic acid equivalent (GAE)/kg dry leaves for Psidium guajava leaves aqueous extract and 15.0 g GAE/kg dry leaves for Carica papaya leaves aqueous extract. The dominant phenolic compounds in Psidium guajava leaves aqueous extract were myricetin (3,852 mg/kg dry sample) and rutin (670 mg/kg dry sample) while the dominant phenolic compounds in Carica papaya leaves aqueous extract were salicylic acid (338 mg/kg dry sample) and rutin (264 mg/kg dry sample). Different metals were also determined (K, Fe, Zn, Ca, Mg, Pb, and Cd) to investigate the potential health claims or hazards in the water extractable infusion, and it was found that no toxic metals were extracted whereas some nutritional benefits were achieved.
Conclusions: Results proved that Psidium guajava and Carica papaya can be provided a strong antioxidant activity and can be used as medicinal plants.
Low copy repeats in the genome: from neglected to respected
Authors: Vervoort Lisanne , Vermeesch Joris R.
Published: April 2023

DNA paralogs that have a length of at least 1 kilobase (kb) and are duplicated with a sequence identity of over 90% are classified as low copy repeats (LCRs) or segmental duplications (SDs). They constitute 6.6% of the genome and are clustering in specific genomic loci. Due to the high sequence homology between these duplicated regions, they can misalign during meiosis resulting in non-allelic homologous recombination (NAHR) and leading to structural variation such as deletions, duplications, inversions, and translocations. When such rearrangements result in a clinical phenotype, they are categorized as a genomic disorder. The presence of multiple copies of larger genomic segments offers opportunities for evolution. First, the creation of new genes in the human lineage will lead to human-specific traits and adaptation. Second, LCR variation between human populations can give rise to phenotypic variability. Hence, the rearrangement predisposition associated with LCRs should be interpreted in the context of the evolutionary advantages.
Abnormal glucose tolerance in children: oral glucose tolerance test is fit-for-purpose
Authors: Law Vivian Yuet Ho , Young Jack Hong Ming , Ng Hak Yung , Chan Louis Tsz Wang
Published: April 2023

Aim: Childhood obesity is accompanied by an increased prevalence of abnormal glucose tolerance (AGT) including the prediabetes states. This study aims to investigate and evaluate the use of oral glucose tolerance test (OGTT) for detecting AGT among overweight and obese children.
Methods: A retrospective study was conducted on 895 overweight and obese Chinese children (6–18 years) with obesity assessment and analysis of demographic, anthropometric, and biochemical parameters data between January 2006 and December 2015 at Tseung Kwan O Hospital, Hong Kong Special Administrative Region.
Results: The proportion of males and older age group was 63.7% and 55.9%, respectively. Girls were more in older age groups (62.7% vs. 52.0%, P = 0.002). AGT occurred in 17.1% of the cohort [impaired glucose tolerance (IGT) was the most frequent morbidity (11.3%)]. After regression analysis, female sex, low-density lipoprotein (LDL), triglyceride (TG), older age group, and homeostasis model assessment of insulin resistance (HOMA-IR) ≥ 4.1 were significantly associated with AGT.
Conclusions: AGT is common in overweight and obese Chinese children. Girls, older age, higher LDL, TG and HOMA-IR ≥ 4.1 showed significant association with AGT. OGTT is essential and fit-for-purpose to detect AGT in overweight and obese children.
Grobplanung roboterbasierter Fließmontagesysteme/Production planning for automotive body shop – model and optimization – Rough Planning of Robotic Assembly Line Systems
Authors: Wrobel Gregor , Ebert Ralf-Erik , Scheffler Robert
Published: April 2023

Zwischen Produktentwicklung und Produktionsplanung besteht seit vielen Jahren eine Digitalisierungslücke. Geeignete Softwarewerkzeuge zur Kosten- und Raumabschätzung in der Phase der Grobplanung roboterbasierter Fließmontagesysteme existieren nicht. Abhilfe schaffen Verfahren zum modellbasierten Engineering, die eine durchgängige und flexible Anlagenplanung ermöglichen. Ein dafür erforderliches Optimierungsverfahren und das ihm zu Grunde liegende Modell werden in diesem Beitrag vorgestellt.

 

A digitization gap has existed between product development and production planning for many years. There is a lack of suitable software tools to estimate the costs and space of robotic assembly line systems. This is remedied by methods of model-based engineering, which allow for consistent and flexible plant planning. The solution involves an optimization procedure developed for this purpose and its underlying model, which enable fast and reliable rough planning.
Humanzentrierte Ablaufplanung von Montagelinien/Human-centered scheduling in assembly lines - Plug and play: Efficient algorithms minimize stress in flow shops
Authors: Vollenkemper Lukas , Grumbach Felix , Kohlhase Martin , Reusch Pascal
Published: April 2023

Angesichts des zunehmenden Fachkräftemangels sind Gesundheit und Zufriedenheit der Beschäftigten von immer größerer Bedeutung für produzierende Unternehmen. Insbesondere bei variantenreichen Produkten müssen Werker und Werkerinnen komplexe Aufgaben erledigen. Diese Variantenvielfalt ist auch für die Produktionsfeinplanung eine Herausforderung. Die vorgestellte Heuristik hilft in einem realen Anwendungsfall Belastungsspitzen an getakteten Linien zu reduzieren und verbessert so die betriebliche Gesundheit.

 

Given a shortage of skilled workers, employee health and satisfaction are of increasing importance to manufacturing companies. Particularly in the case of products with many variants, workers have to perform complex tasks. This diversity of variants is also a challenge for production planning. New planning paradigms help to reduce peaks of stress on flow production and thus contribute to occupational health.
Choice between decision-making strategies in human route-following
Authors: Bock Otmar , Huang Ju-Yi , Onur Özgür A. , Memmert Daniel
Published: April 2023

To follow a prescribed route, we must decide which way to turn at intersections. To do so, we can memorize either the serial order of directions or the associations between spatial cues and directions (“at the drug store, turn left”). Here, we investigate which of these two strategies is used if both are available. In Task S, all intersections looked exactly alike, and participants therefore had to use the serial order strategy to decide which way their route continued. In Task SA, each intersection displayed a unique spatial cue, and participants therefore could use either strategy. In Task A, each intersection displayed a unique cue, but the serial order of cues varied between trips, and participants therefore had to use the associative cue strategy. We found that route-following accuracy increased from trip to trip, was higher on routes with 12 rather than 18 intersections, and was higher on Task SA than on the other two tasks, both with 12 and with 18 intersections. Furthermore, participants on Task SA acquired substantial knowledge about the serial order of directions as well as about cue–direction associations, both with 12 and with 18 intersections. From this we conclude that, when both strategies were available, participants did not pick the better one but rather used both. This represents dual encoding, a phenomenon previously described for more elementary memory tasks. We further conclude that dual encoding may be implemented even if the memory load is not very high (i.e., even with only 12 intersections).
Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme
Authors: Matić Josipa , Tandarić Tana , Radić Stojković Marijana , Šupljika Filip , Karačić Zrinka , Tomašić Paić Ana , Horvat Lucija , Vianello Robert , Tumir Lidija-Marija
Published: April 2023

Two novel conjugate molecules were designed: pyrene and phenanthridine-amino acid units with a different linker length between the aromatic fragments. Molecular modelling combined with spectrophotometric experiments revealed that in neutral and acidic buffered water solutions conjugates predominantly exist in intramolecularly stacked conformations because of the π–π stacking interaction between pyrene and phenanthridine moieties. The investigated systems exhibited a pH-dependent excimer formation that is significantly red-shifted relative to the pyrene and phenanthridine fluorescence. While the conjugate with a short linker showed negligible spectrophotometric changes due to the polynucleotide addition, the conjugate with a longer and more flexible linker exhibited a micromolar and submicromolar binding affinity for ds-polynucleotides and inactivated a mutant of dipeptidyl peptidase enzyme E451A. Confocal microscopy revealed that the conjugate with the longer linker entered the HeLa cell membranes and blue fluorescence was visualized as the dye accumulated in the cell membrane.
Analysis of Weather Factors and Damage Rate of Apple Fruit by Typhoon
Authors:   The Korean Data Analysis Society, Choi Su Hoon , Lee Sang-Hyun , Kim Min Soo
Published: April 2023

Every year, direct and indirect damage to farms caused by natural disasters continues to occur. In particular, damage caused by typhoons appears to cause great damage. This study aims to identify and analyze the relationship between weather factors and damage rate in the event of a typhoon by utilizing the weather information provided by the Korea Meteorological Administration and the damage caused by crop accident insurance. Since the damage rate is proportional data with values between 0 and 1, it is not suitable to utilize standard statistical techniques that assume that the error term follows a normal distribution and has a constant variance. Therefore the analysis is conducted through the binomial regression and the beta regression model. As a result the adjusted R square of the beta regression model was higher than that of the binary regression model. And the minimum air pressure, maximum wind speed, and maximum humidity variables were significant among the weather variables. Through this analysis of the damage rate, it is expected that damage to farms can be reduced by preparing appropriate countermeasures in the event of a typhoon.
A Study On The Optimal Process For Efficient Logistical Transport
Authors:   The Korean Data Analysis Society, Lee Eunju , Cheon Sooyoung
Published: April 2023

With the advent of various online to offline (O2O) services, the transportation volume of logistics companies is increasing. However, since vehicles and car owners are limited, if the shipper does not present an appropriate fare, the rate of allocation will decrease and making it difficult to secure car owners. It is also not easy for car owners to find the most suitable logistics at once amid numerous requests for logistics transportation in real time. For efficient dispatch, we study the dispatch contract process according to each position of the shipper and the car owner. For shippers, we suggest optimal fares with high dispatch probability according to fare decision factors, and check the probability of execution when the optimal fare is presented. For car owners, a personal model using random forest is built to narrow the their choice amid numerous shippers' cargo transport requests, and a customized cargo recommendation list is provided. New car owners use a group model built by grouping car owners with similar tendencies. In addition, in order to reduce the waiting time for car owners, we analyze a method of minimizing the distance that runs without loading. As a result, it is found that the average 29.771 km can be reduced.
Clustering of image annotations using online learning-based LDA model
Authors:   The Korean Data Analysis Society, Hwang Inok , Kim HyangKyung , Lee Ji Won , Kim Seongyong
Published: April 2023

LDA model is one of the latent topic models used to investigate latent topics by analyzing documents and words in corpus, and has been widely used in various fields. However, LDA model proposed by Blei, Ng, Jordan (2003) is based on batch learning, which estimates parameters using whole data at once, which has limitations such as large memory requirement and computation time for large data. To resolve this problems, an online learning-based LDA model has been proposed. This method has been known to consume less memory and have a faster analysis speed than batch learning. In this paper, we investigate the topic of each image by applying an online learning-based LDA model to corpus composed of annotations for more than 10,000 images provided by Visual Genome. For analysis, preprocessing was performed on image annotations. Various combinations of the number of latent topic and several hyper-parameters were set, and measures of perplexity and coherence are compared to find optimal model. As a result of comparison, a model with 10 latent groups was selected, and topics such as ‘human’, ‘animal’, ‘downtown’, ‘sea’, ‘bathroom’, and ‘kitchen’ were derived through the top words of each group.
A Study on the Optimal Model for Estimating the Probability of Informed Trading: A Comparison of MLE and Bayesian Methods
Authors:   The Korean Data Analysis Society, Choi Byungwook
Published: April 2023

This study compares two models for estimating the probability of informed trading (PIN) and investigates which model is superior in the Korean index options market. The study uses the method of maximum likelihood estimation (MLE) and Bayesian methods to calculate the PIN. Using the bid and transaction data (TAQ) of KOSPI 200 index options from May 2019 to September 2020, we obtain the following results. First, there were no cases where there was no solution in either method. Second, when estimating delta using the Bayesian method, no boundary solutions occurred, but with the MLE method, multiple boundary solutions occurred. Specifically, 10% of the total solutions in 5-minute tick data and 47% in 20-minute tick data were boundary solutions. Third, in the case of 20-minute tick data, the PIN estimated by the MLE method for ITM options significantly decreased compared to that of the 5-minute data. This is estimated to be caused by the previous boundary solutions inducing a downward bias in the PIN. Fourth, in the MLE method, the standard error of the estimate is almost zero, while the Bayesian method shows an error rate of around 2% based on PIN from 20-minute data. In conclusion, the Bayesian method is superior when there is no boundary problem, given a sufficient size of closing data, but when not, the magnitude of the error rate is considered to be an important factor in the choice of method.
The validity of the method of successive intervals: A comparison to measures from item response theory
Authors:   The Korean Data Analysis Society, Han Yuhwa
Published: April 2023

The current study aimed to confirm the validity of the method of successive intervals (SI) as a scaling method for stimuli and attributes. In order to achieve this research objective, the measurement of stimuli and attributes calculated by SI and item response theory (IRT) were compared. The blameworthiness of 33 behaviors (stimuli) was measured, and based on the measurement, the psychological attribute of ‘representation of innocence’ was measured. The correlations between the measurements calibrated by SI and IRT were estimated for the blameworthiness and the ‘representation of innocence.’ The theoretical relationship among ‘representation of innocence,’ legal threshold for a guilty verdict (beyond a reasonable doubt), the individual practical threshold for a guilty verdict, and the difference between the two thresholds estimates. These analyses were conducted on the 300 participants (survey sample) collected for this study and replicated on the 360 participants (cross-validation sample) obtained from previous research data. As a result, it was found that the two lists of measures for the blameworthiness of behaviors measured by SI and IRT were positively correlated. However, the correlation of measures of ‘representation of innocence’ from the two methods was observed only in the survey sample. In addition, the ‘representation of innocence’ measured by SI showed a theoretically predicted relationship with the legal conviction standard, and the measurement by the IRT showed the relationship predicted by theory with the actual conviction criteria only in the cross-validation sample. In the discussion, the author demonstrated the validity of SI as a scaling method for stimulus and attribute and suggested the direction for further research.
QUALITY OF BEECH, BIRCH AND OAK WOOD FROM STANDS GROWING ON POST-AGRICULTURAL LANDS
Authors: TOMCZAK KAROL , MANIA PRZEMYSŁAW , TOMCZAK AKRADIUSZ
Published: April 2023

This study assessed the quality of birch, beech, and oak for timber production on former agricultural land. All sample plots for the selected species had the same forest habitat type. All measured trees had already reached the age of felling. Thus, beech was over 120 years old, birch was over 70 years old, and oak was over 140 years old. On each plot, the same morphological features were measured for all trees: diameter at breast height, tree height, height of the first dead branch, height of the first live branch, and crown base. Based on collected data the length and percentage of the trunk suitable for industrial purposes were calculated. In general birch and beech trees from former agricultural land were higher, but had thinner trunks, when in oak reverse observation were noticed. Tree trunks from former agricultural lands have app. 7% shorter knots-free trunk section. The bigger different between forest and former agricultural land was noticed in case of the oak – 14%, then beech – 5% and birch – 1%. Considering the morphological characteristics of the trees and quality indicators, we showed that all species could be used for the afforestation of former agricultural lands to produce high-quality wood for future industrial purposes. However, it should be noticed, that in general calculated standing volume was lower on former agricultural land.
FIXATION OF DYE-TYPE RED AND BLUE INK HANDWRITING ON AGED PAPER
Authors: MI LINHAN , TAN WEI , WU TING , CAI XIAOLAN , PAN CHENQIAN , FANG YANXIONG
Published: April 2023

In this article, red and blue ink handwriting on aged paper was fixed by fixative to prevent handwriting from fading or diffusion during aqueous deacidification. Firstly, four fixatives were selected: polydimethyl ammonium chloride (PDDA), the quaternary ammonium salt of chitosan (HACC), cationic guar gum (CGG), and benzyl triethyl ammonium chloride (TEBAC) alcohol solution, according to their fixation effects on filter paper dyes, and derive the optimal composition ratio of the above four fixatives. Experimentally derived that PDDA has an excellent fixation effect on red ink handwriting, and HACC has an excellent fixation effect on blue ink handwriting. In addition, HACC also has a positive impact on the conservation of handwriting in real archives. The mechanical properties of aged paper were improved, and the paper fibers had no obvious change after the fixation and deacidification processes.
DETERMINATION OF MODE I FRACTURE PROPERTIES OF EUROPEAN SPRUCE
Authors: TODOROVIĆ MARIJA , KOETSIER MATHIEU , SIMOVIĆ NAĐA , GLIŠOVIĆ IVAN , PAVLOVIĆ MARKO
Published: April 2023

In this paper an efficient procedure for obtaining a cohesive law for Mode I timber fracture (crack opening), based on the Double Cantilever Beam (DCB) tests is given. DCB tests were performed on ten European spruce specimens in order to determine the energy release rate vs crack length (R curves). Two crucial parameters - crack length during the experiment and the crack tip opening displacement were obtained using 2D Digital Image Correlation (DIC) technique. In order to determine accurate fracture resistance (R curve), procedure which includes calculating cumulative released energy was employed. The cohesive law for Mode I fracture of wood was obtained by differentiation of the strain energy release rate as a function of the crack tip opening displacement. This cohesive law is further implemented in the successful numerical modelling of failure modes in large-scale end-notched glulam beams which were experimentally tested in four-point bending configuration.
SHORT NOTES: FIRST REPORT OF THE LIGNIVOROUS FUNGUS PAECILOMYCES MAXIMUS IN CEDRUS ATLANTICA M. IN MOROCCO
Authors: CHAUIYAKH OUSSAMA , EL FAHIME ELMOSTAFA , NINICH OUMAIMA , AARABI SAMAR , BOUZIANI MUSTAPHA , CHAOUCH ABDELAZIZ , ET TAHIR AZIZ
Published: April 2023

This study is interested in isolating fungi from the wood parts of cedar trunks withered and identifying these lignivorous fungi. A sample was isolated from the cedar grove of Tazekka National Park located south of the city of Taza in Morocco. The culture and purification of the isolated fungus were done on a water agar medium and then on a PDA medium. After the purification of the fungus, a morphological study by scanning electron microscope allowed us to identify the pathogen Paecilomyces. A molecular characterization identified Paecilomycesmaximus with a coverage percentage of 99% and an identity of 98.77%. To our knowledge, this is the first report of P. maximus in decayed cedar wood.
New records of bivalves from the Iraqi coast
Authors: Yasser Amaal Gh. , Naser Murtada D. , Abdul-sahib Ibtisam M. , Abdullah Dawood S.
Published: April 2023

Six marine bivalves species were recorded from the north west of the Arabian Gulf, Iraqi coast from 2020 to 2021. The species are Acar plicata (Dillwyn, 1817) (family Arcidae), Sunetta effossa (Hanley, 1843) (family Veneridae), Scissileda tropica (Melvill, 1897) (family Yoldiidae), Protapes cor (Sowerby, 1853) (family Veneridae), Circentia callipyga (Born, 1778) (family Veneridae) and Acrosterigma lacunosa (Reeve, 1845) (family Cardiidae). These records raise the number of marine bivalves known from the Iraqi coast to 38 species.
TOXICIDADE DE PARACETAMOL EM SEMENTES DE ALFACE (LACTUCA SATIVA)
Authors: Araújo Vanessa De Fátima Carneiro De , Souza Juce Silva de , Oliveira Karolayne Janilda Lima de , Barros Michele Menezes de , Pereira Wanderson Cunha , Comassetto Thaisa Pegoraro
Published: April 2023

Este trabalho teve como objetivo avaliar a toxicidade do fármaco paracetamol por meio de bioensaio em sementes de alface. O experimento, realizado em placas de petri, foi instalado em laboratório, com delineamento inteiramente ao acaso, com 5 tratamentos (água destilada = 0 mg L-1; 2,7 mg L-1; 5,0 mg L-1; 9,3 mg L-1 e 15 mg L-1) e 4 repetições. As parcelas experimentais, placas de petri, foram compostas por 10 sementes de alface, cujas variáveis analisadas foram o número de sementes germinadas, crescimento da radícula e do hipocótilo (mm) de cada semente, e peso (mg) das 10 sementes. Estas foram submetidas à Análise de Variância (α = 0,05) e ao Teste de Tukey (α = 0,05) para comparações das médias quando necessário. As concentrações de paracetamol de 2,7 mg L-1 e 15 mg L-1 causaram redução no crescimento da radícula em 30% e 82%, respectivamente. No crescimento do hipocótilo, tais concentrações afetaram em 53% e 83%, respectivamente. Já no peso tais concentrações afetaram em 45% e 66%, respectivamente. Nas condições em que esse experimento foi realizado, o fármaco paracetamol foi tóxico para o desenvolvimento das plântulas de alface.