bluuebunny/crossref_metadata_2025 huggingface dataset:
Diferentes usos do ultrassom na terapia da doença de Alzheimer
Authors: Gomes Pereira Vinícius , Furtado Cunha Guilherme , Do Paço Baylão Antônio Guilherme , Ramos Caleare Estella , Silveira Guimarães Patrick , Ribeiro Dias Barroso Cristina
Published: August 2024

Introdução: A Doença de Alzheimer (DA) é um distúrbio neurodegenerativo relacionado à idade. Microscopicamente, é caracterizada por perda neuronal através da degeneração sináptica intensa, formação de emaranhados neurofibrilares e deposição de proteína β-amilóide no cérebro com formação de placas senis (RAYMOND et al., 2011). O ultrassom tem sido usado e testado de variadas formas no tratamento e diagnóstico da DA. Diferentes tipos de ultrassom têm apresentado possibilidades variadas na modificação da fisiologia e do crescimento neuronal (SCARCELLI et al., 2014). Objetivos: Revisar a possibilidade de uso dos diferentes tipos de ultrassom no tratamento da Doença de Alzheimer. Método: Trata-se de uma revisão narrativa em que foram feitas buscas na base de dados Pubmed-Medline, com as palavras-chave “Alzheimer’s Disease” e “Ultrasound”. Resultados: Foram encontrados vários estudos sobre o uso do ultrassom no tratamento e diagnóstico da DA. Desses, foram selecionados os mais relevantes para a discussão do tema, focando em artigos em que o texto completo estava disponível. O principal uso do ultrassom como forma terapêutica, tendo como parâmetro o número de artigos encontrados, foi o aumento da permeabilidade da BHC, sendo que a maioria ainda estava em fase de teste. Discussão: O uso do ultrassom como forma terapêutica na DA ainda é uma possibilidade nova, sendo desenvolvida de variadas formas, com o objetivo de aumentar a probabilidade de criação de um tratamento eficiente aplicável em humanos. O ultrassom transcraniano focalizado (Transcranial focused ultrasound – FUS) guiado por Ressonância Magnética pode ser utilizado para terapias cerebrais não invasivas (SCARCELLI et al., 2014). Por exemplo, FUS, em baixas intensidades, pode ser usado para aumentar a permeabilidade da barreira hematoencefálica (BHC), facilitando o acesso de terapias farmacológicas e imunoterapias do sangue ao cérebro (BURGESS et al., 2014; JORDÃO et al, 2010; HYNYNEN el al, 2001; KINOSHITA et al., 2006). Além disso, FUS em baixas intensidades também tem demonstrado propriedades noeuromodulatórias (MIN et al., 2011; KIM et al., 2012) e a habilidade de aumentar fatores de crescimento (TUFAIL et al., 2010), incluindo o Fator Neurotrófico Derivado do Cérebro (BDNF), que é capaz de promover neurogênese em adultos (JIN et al., 2002). Em outra instância, testes clínicos com o SUS (repeated scanning ultrasound) já demonstram que o ultrassom consegue remover a proteína β-amilóide e restaurar a memória em modelos de DA em ratos (LEINENGA & GÖTZ, 2015). Conclusão: O ultrassom, portanto, tem uma vasta possibilidade de aplicação no tratamento da DA e, apesar de muitos desses tratamentos ainda estarem em fase de teste, as perspectivas para o futuro são positivas.
Insuficiência renal crônica e o uso de anabolizantes
Authors: Molina da Silva Camila , Alves Pereira de Oliveira Glenda , Maia Cezar Laís , Nasraui Calçada Rafaela , Vieira Canettieri Rafaela , Spolidoro Maia Rita , Fernandes Malta Yolanda
Published: August 2024

Introdução: A Insuficiência Renal Crônica (IRC) é a síndrome clínica decorrente da incapacidade dos rins de manter suas funções de depuração de escórias nitrogenadas, regulação da volemia, pressão arterial, equilíbrio hidroeletrolítico e acidobase, produção de hormônios etc., com consequências como hipertensão arterial, edema, congestão, anemia, acidose e diversas outras complicações, além do agravamento de comorbidades e aceleração da aterosclerose. Sabe-se que o uso de esteróides anabolizantes traz muitos danos a diversos órgãos do corpo humano, inclusive os rins. Deve-se atentar para ampla divulgação das consequências que o uso dessas substâncias pode trazer, pois, dessa maneira, é possível prevenir que usuários desinformados desenvolvam lesão ou até falência renal. Objetivos: O objetivo deste trabalho é evidenciar os riscos do uso de esteroides anabolizantes, assim como os danos irreversíveis que podem causar aos rins. Relato de caso: Paciente N.L.S., 29 anos, sexo masculino, natural do Rio de Janeiro – RJ e residente de Volta Redonda – RJ. Relata ter apresentado quadro de erisipela em membro inferior esquerdo que tratou com penicilina, levofloxacina e duas injeções de benzetacil. Evoluiu com cefaleia, náusea e distúrbios do sono, procurando a unidade básica de saúde, onde foi detectado um pico hipertensivo. Foi encaminhado ao hospital, onde foram realizados exames complementares, que, juntamente com a história de uso de anabolizantes por um ano, possibilitaram o diagnóstico de insuficiência renal crônica. O paciente iniciou imediatamente a hemodiálise, sendo este o único tratamento eficaz. Conclusão: É evidente a importância da realização de exercícios físicos para manutenção da saúde, porém a busca por melhores resultados, muitas vezes, leva ao uso de substâncias que podem trazer muitos riscos ao organismo. A lesão renal causada pelo uso de esteroides anabolizantes é rara e sua fisiopatologia ainda é desconhecida, por isso é imprescindível a exclusão de outras possíveis causas da insuficiência renal crônica. O tratamento da IRC consiste em diálise ou transplante renal. É necessário manter os cuidados de suplementação de bicarbonato, controle da hiperfosfatemia, hipocalcemia e hiperparatireoidismo, correção da anemia, controle rigoroso da hipertensão, diabetes e outras comorbidades, complicações e fatores de risco de doenças cardiovasculares.
O auxílio da ressonância nuclear magnética no diagnóstico da esclerose múltipla
Authors: Silva Guimarães de Souza Alana Rafaela , Lana dos Santos Moreira Cinthia , Guimarães de Oliveira Juliano , Jun Osugue Gustavo
Published: August 2024

Introdução: A Esclerose Múltipla é uma doença crônica de caráter dismielinizante do sistema nervoso central. O diagnóstico feito apartir dos achados clínicos do paciente, que, geralmente, apresenta sua doença em surtos episódicos e, com o passar do tempo, esses episódios vão apresentar um menor intervalo de tempo entre eles. O uso da ressonância nuclear magnética após alguma síndrome isolada, caso revele lesões padrões da doença, indica que o paciente tem 85% de chance de desenvolver a doença. Objetivos: Demostrar como a ressonância nuclear magnética pode auxiliar na descoberta de possíveis casos de esclerose múltipla em paciente que já apresentaram alguma síndrome clínica isolada. Metodologia: Foi realizado um estudo revisional em casos clínicos de pacientes com esclerose múltipla que foram diagnosticados precocemente, devido ao auxilio da ressonância, que revelou lesões padrão, apesar de o paciente não apresentar toda sintomatologia e não estar em uma fase avançada da doença. Resultados: Foi constatado que, quanto mais precocemente a Esclerose Múltipla é diagnosticada, melhor o prognóstico e padrão de vida vai apresentar o paciente. Discussão: Quando é necessário o uso da ressonância nuclear magnética em pacientes que apresentarem um padrão de síndrome clinica isolada condizente com um quadro de esclerose múltipla, levando em consideração o valor do exame. Conclusão: É necessário identificar as síndromes clínicas isoladas que denunciam uma possível esclerose múltipla, principalmente quando se tratar de uma neurite óptica retrobulbar, utilizando-se a ressonância como exame complementar para procurar lesões e prevenir uma possível evolução da Esclerose Múltipla.
Prognóstico de transtorno obsessivo-compulsivo (TOC) em adolescentes
Authors: Rodrigues Novaes Eduardo , Casiraghi Pançardes Bruna
Published: August 2024

Introdução: O transtorno obsessivo-compulsivo (TOC) é um distúrbio psiquiátrico que se caracteriza pela presença de pensamentos obsessivos e compulsivos. Essa afecção acarreta diversos prejuízos para a vida dos adolescentes, de forma que o prognóstico da mesma deve ser considerado. Objetivo: Este artigo tem por objetivo abordar o prognóstico de Transtorno Obsessivo-Compulsivo em adolescentes, baseando-se em artigos e publicações de 2012 e 2013, objetivando elucidar melhor os aspectos relacionados ao mesmo. Método: Revisão de forma sistemática dos artigos referentes aos anos de 2012 e 1013 a respeito do Prognóstico de TOC em adolescentes, revisão bibliográfica ou ensaios críticos obtidos através de pesquisa no banco de dados BVS (Biblioteca Virtual em Saúde), leitura, confecção de planilha, resumo crítico e análise comparativa dos artigos. Discussão: A análise comparativa dos artigos demonstra convergência destes quanto à forma de abordagem dos tópicos avaliados, associando-os quanto a informações cujos pensamentos se complementam. No geral, o prognóstico não é muito bom. A TCC apresenta-se como principal forma terapêutica, e os IRS apresentam eficácia quanto a tratamento farmacológico. A família possui papel fundamental para o desenvolvimento do prognóstico do paciente, sendo fonte de apoio para o mesmo. Conclusão: Sugere-se maior esclarecimento quanto à forma ideal do tratamento no adolescente, assim como o desenvolvimento de um maior número de estudos a respeito de como se desenvolve o prognóstico do TOC em adolescentes, já que o mesmo influi de forma drástica na vida dos mesmos e se associa a condições ruins, já que, na grande maioria dos casos, não há ocorrência de remissão completa dos sintomas.
Sustainability beyond the surface: Evaluating the long-term environmental and energy performance of selected cladding materials for housing retrofits
Authors: Alegbe Mark , Hammed Nasuri
Published: August 2024

External walls, constituting the largest exposed surface area of the building envelope, face heightened susceptibility to environmental influences. In this study location, aesthetic con- siderations often overshadow environmental impact and comfort requirements in selecting exterior cladding materials. This paper investigates the energy performance, global warming potential, and thermal comfort aspects of carefully selected cladding materials, informed by an exhaustive literature review, for application in retrofit projects in Abuja, Nigeria. Energy con- sumption, carbon emissions, and temperature distributions were simulated using materials in a hypothetical single-floor residential building finished with cement-sand plaster. The findings show that gravel stone exhibits the most negligible environmental impact. In contrast, alumi- num and lightweight metal cladding panels contribute significantly to the embodied carbon of the building despite ranking as the most expensive materials. Insulating the test building with polyurethane boards yields substantial energy savings of up to 9% in cooling electricity, averting the need for added cladding. This study emphasizes the significance of adopting a multi-criterion approach in selecting façade cladding materials, prioritizing environmental and thermal considerations over aesthetic and cost benefits. The implications extend beyond mere emissions reduction, shedding light on the vital interplay between material choices on comfort and energy efficiency in building design.
Simulations of IDCR and SOWER Antarctic minke whale abundance surveys
Authors: Palka Debra L. , Smith Daniel W.
Published: August 2024

The International Whaling Commission (IWC) conducted abundance line‐transect surveys of Antarctic minke whales (Balaenoptera bonaerensis) during the International Decade of Cetacean Research (IDCR) between 1978/79 and 2003/04. These surveys continued throughout 2004/05–2009/10 under the Southern Ocean Whale and Ecosystem Research (SOWER) programme. Several methods used to analyse these data resulted in very different abundance estimates. In order to evaluate the accuracy of these methods, the IWC Scientific Committee recommended using simulated line‐transect data. The software package TRANSIM was therefore modified to generate simulated line‐transect data that emulated an IDRC/SOWER survey in a study area populated with whales that followed the distribution, density and behaviour of Antarctic minke whales. Simulations incorporated factors that could potentially bias resulting abundance estimates, and in order to investigate the effects of these factors on the resulting abundance estimates, simulated datasets were generated for different scenarios, each of which incorporated combinations of factors that were chosen using the mirror‐image fold‐over partial factorial method that is designed to identify factors related to biased estimates. This paper describes the programme used to generate these datasets and reports on the robustness of the statistical methods applied to analyse them. In addition, a brief discussion is included on how this information was used when the actual line‐transect data were analysed. The statistical methods investigated were the hazard probability method (OK), integrated hazard probability method (IM), spatial point independence method (SPL) and standard method. After developers analysed the simulated data, they used this information to improve their analytical methods. The results reported here focus on the performance of the most advanced versions of the OK and SPL methods compared with the standard method as of 2009. In general, SPL estimates of group density were negatively biased, OK estimates were positively biased, standard estimates were the most negatively biased and IM estimates were the least biased. Density estimates from SPL were less biased than estimates from OK in the complex scenarios that contained spatial gradients and correlations between density, location and weather conditions. The OK method was less robust when: (1) closing‐mode data collection procedures were simulated; (2) whale groups were diving in a non‐synchronous fashion; and (3) there were complex spatial patterns. In almost every case, the density estimates from the OK method were greater than the SPL methods, on average by 10–15%. These observations assisted the development of more robust analysis methods and highlighted which factors should be addressed when analysing the actual data.
The effect of organizational culture and work motivation on performance employees with organizational commitment as intervening variables (Study at the Merauke Regency DPRD Office, Mappi Regency, Asmat Regency, Boven Digoel Regency)
Authors: Layan A. Isaak R. J. , Erari Anita , Handoyo Sarwo Edy
Published: August 2024

This study aims to determine the effect of organizational culture and work motivation on the performance of secretariat employees of the Regional House of Representatives with organizational commitment as an intervening variable in Merauke Regency, Mappi Regency, Asmat Regency, Boven Digoel Regency. The population in this study were 233 regional secretariat employees and by using purposive sampling, 106 respondents were determined. The results showed that organizational culture had a positive and insignificant effect on employee performance. Organizational culture has a positive and significant effect on employee commitment. Work commitment mediates the relationship between the influence of organizational culture on employee performance. Motivation has a positive and significant effect on employee performance. Motivation has a positive and insignificant effect on employee commitment. Work commitment does not mediate the relationship of the influence of motivation on employee performance. Organizational commitment has a negative and insignificant effect on the performance of the secretariat employees of the People's Representative Council of Merauke, Boven Digoel, Mappi, and Asmat Districts.
Leveraging Hyperforce for Scalable and Secure Multi-Cloud Solutions: An Architectural and Implementation Guide
Authors: Chary Divya
Published: August 2024

Purpose: In today’s fast-paced digital world, businesses are turning to multi-cloud strategies to boost their performance, flexibility, and resilience. This paper aims to provide a straightforward guide on leveraging Salesforce’s Hyperforce in a multi-cloud environment. Hyperforce is designed to work with major public cloud providers, offering unmatched scalability, data residency compliance, and efficiency. The primary objective is to help IT professionals and decision-makers fully leverage Hyperforce in a multi-cloud strategy to drive digital transformation and maintain competitiveness.
Methodology: This paper explores the key aspects necessary for a successful Hyperforce and multi-cloud setup, including architectural design, implementation steps, data management, security, performance optimization, and cost management. Through a combination of clear technical insights and real-world examples, the paper illustrates the challenges and best practices associated with implementing Hyperforce in a multi-cloud environment.
Findings: By spreading workloads across different cloud platforms, companies can enhance redundancy, avoid vendor lock-in, and optimize resource utilization. The paper identifies critical areas such as architectural design, security, and cost management that are essential for successful multi-cloud adoption using Hyperforce. Additionally, the paper delves into emerging trends and future innovations in the multi-cloud space, providing insights into the evolving landscape and what lies ahead for Hyperforce.
Unique Contribution to Theory, Practice and Policy: The paper recommends that IT professionals and decision-makers focus on fully understanding and utilizing Hyperforce’s capabilities within a multi-cloud strategy. This involves following best practices in architectural design, implementation, data management, and security to maximize the benefits of Hyperforce. The insights and tools provided in this paper are intended to equip organizations with the knowledge necessary to effectively implement Hyperforce and drive their digital transformation efforts forward.
Influence of Board Diversity on Firm Performance and Sustainability in Kenya
Authors: Wairimu Florence
Published: August 2024

Purpose: The aim of the study was to examine the influence of board diversity on firm performance and sustainability.
Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.
Findings: diversity on corporate boards, whether in terms of gender, ethnicity, age, or cultural background, has consistently shown positive correlations with financial performance metrics, innovation outputs, ethical governance practices, and corporate social responsibility efforts. The study suggests that diverse boards are better equipped to navigate challenges, capitalize on opportunities, and enhance stakeholder engagement.
Unique Contribution to Theory, Practice and Policy: Resource Dependence Theory, Agency Theory & Institutional Theory may be used to anchor future studies on Influence of Board Diversity on Firm Performance and Sustainability. Organizations should prioritize inclusive board recruitment practices that actively seek out diverse candidates based on gender, ethnicity, age, skills, and cultural backgrounds. This proactive approach ensures that boards reflect the diversity of their stakeholders and leverage a broader range of perspectives to drive innovation, resilience, and sustainable practices. Boards and senior management teams should invest in diversity training and education programs that promote awareness, sensitivity, and inclusion. Policymakers should consider enhancing regulatory guidelines that encourage transparency and accountability in board diversity disclosures. Clear reporting requirements on board composition, diversity metrics, and diversity initiatives can incentivize organizations to prioritize diversity as a strategic imperative and promote greater board diversity across industries and sectors.
Exploring The Relationship between Injury, Addiction, and Physical Activity: A Path to Recovery for Athletes
Authors: Elmadhoun Sumaya , Mansi Mohammed , Kamal Rama , Al-Kuwari Khalifa , Mohamed-Ali Vidya , Al-Maadheed Mohammed
Published: August 2024

Elite, professional athletes face elevated levels of stress, anxiety, or depression, which sometimes lead to use of illicit substances to mitigate stress by self-medication.This study aimed to highlight the need for developing tailored, exercise mediated approaches to recovery from substance use disorders (SUD) and alcohol use disorders (AUD), offering significant benefits for athlete-specific rehabilitation, and reintegration into their social and professional environment
Partisi Ruang Berdasarkan Kebutuhan Pengguna Dengan Konsep Industrial
Authors: Rachmawati Syerlina , Marwahyudi  , Seftianingsih Dina Kristiana
Published: August 2024

Along with the development of the era, human desires for housing are increasingly diverse, where houses are not only for carrying out daily activities and carrying on life, but also become a means of inspiration and indicate social levels in the community. The design object to be appointed is the residence of Mr. Antok Suharno which is located in the village of Mulyorejo, Mojosongo District, Boyolali Regency. The residence previously did not have a concept, the Industrial concept became the design theme plan to be implemented. The design objective is to create privacy for the living room and dining room that meets user comfort in accordance with the comfort theory by presenting a partition, functioning as a separator as well as maintaining privacy and presenting decorative value between the living room and dining room. The data collection method is by surveying, measuring and documenting the location of Mr. Antok Suharno's residence, collecting user data for each room and interviewing Mr. Antok Suharno as the owner of the house. Partitions designed to apply materials in accordance with the Industrial concept, namely with black hollow iron material, multiplex and vinyl finishing with wood motifs. The results of the partition design have a length of 180cm, a width of 30cm and a height of 200cm.
Pusat Salon Kecantikan Griya Cantik merupakan suatu usaha yang memfasilitasi seseorang yang ingin mendapatkan pelayanan perawatan dari rambut, wajah, makeup, pelayanan rileksasi seperti spa, sauna, body massage, ratus yang dikhususkan bagi para perempuan.
Authors: Fatma Safira Nurul Ardinda
Published: August 2024

Pusat Salon Kecantikan Griya Cantik merupakan suatu usaha yang memfasilitasi seseorang yang ingin mendapatkan pelayanan perawatan dari rambut, wajah, makeup, pelayanan rileksasi seperti spa, sauna, body massage, ratus yang dikhususkan bagi para perempuan. Pemilihan nama Griya Cantik sebagai nama salon menjurus kepada bangunan tempat salon yang merupakan sebuah bangunan bekas rumah tinggal dan arena salon tersebut yang beroperasi di tengah kawasan perumahan warga. Oleh karena itu berdasarkan tingkatannya, Pusat Salon Kecantikan Griya Cantik termasuk dalam Salon Kelas D dikarenakan lokasinya yang berada di daerah perumahan. Perancangan ini dimaksudkan untuk merancang pengisi ruang berupa vanity table yang sesuai dengan fungsi dan aktivitas pengguna. Dalam melakukan perancangan, dilakukan beberapa metode pencarian data melalui observasi secara langsung hingga melaui studi literature, wawancara, hingga mengumpulkan dokumentasi yang berhubungan dengan objek. Pengambilan konsep Art Deco didasarkan pada hasil metode pencarian sehingga diterapkan pada desain vanity table sehingga menghasilkan desain yang berkarakter dengan mempertimbangkan esetetika, serta fungsinya.
Assessment of Psoriasis Severity Using Psoriasis Area and Severity Index (PASI) and its Association with Lipid Profile Parameters
Authors: Jawed Iqbal  , Aamir Hussain  , Rizwan Ali Talpur  , Hafiz Bashir Ahmed Kalhoro  , Hanozia Shah  , Andleeb
Published: August 2024

Objective: To explore potential association between specific lipid profile parameters and PASI scores in psoriatic patients at a tertiary care Hospital.
Methodology: A descriptive cross-sectional study was carried out on patients attending the skin outpatient department and the Diagnostic Research Laboratory of the Department of Physiology at Liaquat University of Medical & Health Sciences Jamshoro/Hyderabad, from February to August 2022.  Diagnosed patients of Psoriasis between 18 and 50 years, male and female were included. A 5ml blood sample was taken from each participant in fasting and the samples were used to perform a lipid profile analysis. All financial costs related to the investigations were covered by the researchers.
Results: The average age of patients with psoriasis was 45.99±10.33 (range 18-60 years). Out of the total 102 patients, 76 (74.5%) were male patients and 26 (25.5%) were female. The mean duration of psoriasis was 6.46 ± 4.49 years. For total cholesterol, 60 patients (58.8%) had increased levels > 200 mg/dL, in 68 patients (66.7%) low-density lipoprotein (LDL), increased levels > 130 mg/dL, in terms of high-density lipoprotein (HDL), in (57.8%) patients it was <40 mg/dL, while for triglycerides, in (87.3%) patients had increased levels > 150 mg/dL. Patients with moderate and severe psoriasis exhibited higher rates of abnormal lipid profiles compared to those with mild psoriasis. Significant p-values were found for total cholesterol, LDL, and HDL levels, indicating associations with psoriasis severity. However, triglyceride levels showed no significant difference across the severity groups.
Conclusion: This study revealed elevated lipid profiles among psoriatic patients, potentially contributing to lipid profile abnormalities. The high frequency of dyslipidemia observed is closely linked to the severity of psoriasis.
Jornalismo Artificial? Desafios e tendências do Jornalismo frente à Inteligência Artificial
Authors: Botelho-Francisco Rodrigo , Flores Vivar Jesús Miguel
Published: August 2024

Atualmente, o ecossistema mediático e de informação, com as suas variadas manifestações de Inteligência Artificial (IA) e incógnitas sobre a ética e fiabilidade das notícias, pinta um quadro brilhante, em alguns casos, e com certo pessimismo, noutros. Por esta razão, organizações noticiosas e universidades em todo o mundo estão a começar a investigar, explorar e experimentar a IA e a sua utilização na criação de conteúdos digitais. Desde o lançamento do ChatGPT, em novembro de 2022, surgiram centenas, e talvez milhares, de trabalhos acadêmicos sobre a utilização desta tecnologia, que vem se consolidando nas organizações noticiosas e demonstrado tanto impacto e potencial para o Jornalismo que a inovação impulsionada pela IA se tornou foco de quase todas as redações.
O parâmetro locação na Língua Brasileira de Sinais
Authors: Libano Alves Bruna Estefani , Pizzio Aline Lemos
Published: August 2024

Este artigo apresenta um recorte de uma pesquisa mais ampla que investigou o parâmetro locação na Língua Brasileira de Sinais (Libras). Inicialmente introduzido nas pesquisas sobre a Língua Americana de Sinais (ASL) na década de 60 por Stokoe, o parâmetro locação é um dos três parâmetros fonológicos básicos da ASL, juntamente com configuração de mão (CM) e movimento (M). Embora tenha sido adaptado para a Libras com base nas propostas de Friedman por Ferreira-Brito em 1995, a descrição fonético-fonológica das locações dos sinais na Libras ainda é incipiente. Neste estudo, partimos da hipótese de que os sinais da Libras podem apresentar mais de uma locação principal e que essas locações principais podem ser compostas de sublocações. Utilizando um corpus de 3068 sinais selecionados a partir do Libras Signbank, analisamos 327 sinais para identificar aqueles que apresentam múltiplas locações principais e sinais com mais de uma sublocação. Os resultados revelaram que, dentro do corpus analisado, alguns sinais apresentam mais de uma locação principal e, em alguns casos, também possuem sublocações. As sublocações foram categorizadas em três tipos: sinais com ambas as sublocações ancoradas no corpo, sinais com uma sublocação ancorada no corpo e outra não-ancorada, e sinais com sublocações no espaço neutro, ou seja, com duas locações não-ancoradas. Além disso, observamos que existe uma distinção entre locações, sublocações e pontos de contato nos sinais, contribuindo para um aprofundamento dos estudos fonético-fonológicos da Libras e uma melhor compreensão da complexidade desse parâmetro na língua de sinais brasileira.
Hypogenic caves of Syracuse area, Sicily (Italy): geomorphological evidence of CO2 degassing, fresh-salt water mixing, and late condensation corrosion
Authors: Audra Philippe , Bigot Jean-Yves , Cailhol Didier , Camps Pierre , D'Angeli Ilenia M. , Cheng Hai , Edwards R. Lawrence , Gàzquez-Sanchez Fernando , Koltai Gabriella , Madonia Giuliana , Nobécourt Jean-Claude , Temovski Marjan , Vattano Marco , De Waele Jo
Published: August 2024

Many caves in Sicily have been shown to have a sulfuric acid or other hypogenic origin. We studied three caves (Palombara, Scrivilleri, Monello) near Syracuse (eastern Sicily), in an area that was strongly uplifted and faulted, creating multiple Pleistocene marine terraces. Mineralogy, stable isotopes and dating methods (paleomagnetism, U/Th) were used to characterize cave sediments, some of which were related to the initial hypogenic phase (Fe and Mn oxides, calcite spar), others were introduced by surface runoff later. Many other sediments are the result of in situ weathering, such as lime sands produced by condensation-corrosion processes on the calcarenite walls. Phosphates, kaolinite and montmorillonite are related to bat guano decay. Stable isotopes show that the speleothems derive from surface seepage with temperatures similar to the present, with no evidence of a hydrothermal origin. Other deep sources of aggressivity are also excluded. We obtained an age of 603 ka for a marine notch deposit near Palombara, as well as a possible paleomagnetic inversion (>780 ka) for clastic allogenic sediments. These ages are discussed, raising the question of the reliability of calculations extrapolated from marine terrace dating and the possibility that the caves may be older than expected. Cave morphologies clearly indicate a hypogenic phase, with aggressive ascending flows creating the typical Morphologic Suites of Rising Flow (MSRF). The bubble trails and acid notches are formed by carbonic degassing and subsequent acidification in more or less closed aerated environments at the water table. Carbon dioxide probably derived from both the bedrock and the oxidation of surface-derived organic carbon at the density boundaries of the freshwater lens. We propose a mixed Flank Margin Cave and hypogenic speleogenesis model, where dissolution was favored in areas of greater CO2 concentration, producing phreatic maze patterns recording past sea-level positions. We suggest that aggressiveness of the rising fluids could have partly originated at a shallow depth, in the mixing zone between fresh and salt water.
Psychological factors and health-related quality of life in fibromyalgia patients
Authors: Campos Ricardo P. , Vázquez Isabel , Vilhena Estela
Published: August 2024

Background

Fibromyalgia (FM) has been associated with decreased health-related quality of life (HRQoL), which has been linked to psychological variables such as anxiety, depression, coping, and social support. This study aimed to simultaneously analyse the association of these variables with HRQoL in FM patients and explore their mediating role in the relationship between somatic symptoms and HRQoL.

Participants and procedure

A cross-sectional sample of 134 FM patients (97% women) with no other rheumatologic diseases followed in specialized healthcare services completed self-report questionnaires to evaluate pain, fatigue, sleep, anxiety, depression, coping, social support, and HRQoL.

Results

The results indicated that FM patients experienced a negative impact on all dimensions of HRQoL, with anxiety primarily affecting the mental dimensions, and depression and social support affecting both physical and mental dimensions. Anxiety, depression, dysfunctional coping, and low social support were independent predictors of HRQoL and mediated the effect of somatic symptoms in the mental component of HRQoL.

Conclusions

FM patients experience a negative impact on HRQoL, and anxiety, depression, coping and social support play an important role as independent predictors of this decrease, and as mediators of the effect of somatic symptoms in the mental dimen-sions of HRQoL. This underscores the importance of considering these psychological variables in the therapeutic approach to FM and suggests the need for interventions targeting anxiety, depression, dysfunctional coping, and low social support to improve HRQoL in FM patients.
Improving Students Ability in Pronunciation Through Reading Aloud for the 8th Grade of SMPN 2 Bukittinggi
Authors: Mardiah Ainun , Safitri Loli , Eliza Eliza , Syahrul Syahrul
Published: August 2024

This research aims to describe the improvement in students' pronunciation through reading aloud. Based on the problem found by the reseracher most of the students have difficulty in pronouncing some words in English such as minimal pairs. Many students did not achieve the completenes criteria (KKM) namely 70, meanwhile the average students score was only 55,15. This research used classroom action research (CAR) that consisted of 2 cycles. The subjects of this research were grade 8 of SMPN 2 Bukittinggi consisted 32 students.The instruments used were oral tests and observations sheet. In analyzing the data, this research used quantitative and qualitative data. Quantitatively, data was obtained from student scores in pronunciation test. Qualitative data was obtained from the results of observation sheet. The results obtained in the first test cycle showed an average student score of 61,68, with a percentage of succsess only 37,5% or 12 out of 32 students who passed the KKM, meanwhile in the second cycle the percentage of success in improving students' pronunciation was 81.25% with an average score of 76,15 where there was 26 students who passed the KKM. The increased from cycle 1 to cycle 2 was 23,45%. In observations sheet, researcher found that used reading aloud can improve students' pronunciation abilities, seen from accuracy and fluency aspect. this was strengthened by observations that showed the classroom situation is also more conducive and students more interested and enthusiastic during the teaching and learning process. In other words, it can be concluded that reading aloud can improve students' pronunciation abilities.
The efficiency of pigs from different genetic origins under industrial conditions in Ukraine
Authors: VOLOSHYNOV Vasyl , POVOD Mykola , MYKHALKO Oleksandr , VERBELCHUK Tetyana , VERBELCHUK Serhii , KOBERNIUK Vira , LAVRYNIUK Oksana , SHCHERBATIUK Natalia
Published: August 2024

The study investigated the dependence of the fattening qualities of pigs and the economic efficiency of their breeding on their genetic origin. Two groups of 28 sows of Danish and Canadian origin inseminated with semen from Durok boars served as research material. A control group consisted of F1 sows of the Landrace and Large White Danish breeds inseminated with semen from Danish Durok boars. The group II, on the other hand, consisted of F1 sows of similar breeds from Canadian selection inseminated with semen from Canadian Durok boars. The studies focused on the efficiency of the sows' reproductive function, the growth intensity of the hybrid piglets and the efficiency and profitability of their rearing and fattening. Methods of analogue pairs and statistical data analysis were used. It was found that piglets of Canadian origin had a 7.5% higher average head weight during the weaning period, which contributed to a 7.5% higher market value and at the same time to a 6.7% higher income from rearing a piglet during this period and to a 3% higher profitability of its rearing compared to analogues of Danish origin. It was shown that animals of Danish origin had a 9.6% higher gross growth of the piglet litter during the fattening period, which gave them a 7.6% higher weight at the end of the fattening period and contributed to a 7% higher cost price for this period, a 7.6% higher market value and a 10.1% higher feedlot income and a 0.77% better feedlot profitability compared to Canadian-bred counterparts. We recommend the use of sows of Danish origin if the farm intends to sell weaned piglets, in the industrial farms. If the farm intends to sell full-grown or (fattened) slaughter pigs, it is advisable to use pigs of Canadian origin.
Sagas of Triumphs of Leading School Heads’ Organizational Landscape Initiatives
Authors: Sacluti Joy V.
Published: August 2024

Outstanding school leaders play a vital role in creating a successful educational environment that can positively impact organizational landscape initiatives. Thus, exploring the stories of triumphs of leading school heads who implemented innovative and effective initiatives is essential. The study purposively selected five (5) outstanding school heads who have outstanding performance in leadership. They have been awarded by the School Division Office of Laguna during the Awarding of Gawad Marangal Year 2020-2023. The data were analyzed using a Narrative Case study. It aimed to capture the narratives of these school heads and gain insights into the strategies, challenges, and outcomes of their organizational landscape initiatives. The study revealed that these leading school heads demonstrated exceptional leadership skills and strategic thinking in implementing organizational landscape initiatives. They were able to create a transformative educational environment by effectively engaging stakeholders developing innovative programs and fostering a culture of collaboration. Their initiatives resulted in improved student performance, enhanced teacher effectiveness and satisfaction, increased parent and community involvement, and overall positive changes in the school’s organizational landscape. They had set high standards of success for their schools by cultivating a proactive and collaborative learning environment. Their optimism, resiliency, and being a relational type of leader have seen them through the myriad of difficulties as school leaders. They stressed that they should be the agents of change in their schools, inspiring others to work hard to achieve their goals and continuously improve. Outstanding school heads typically use one of two approaches: transformational or democratic leadership. With their leadership philosophies, they were more successful at managing employees and creating an atmosphere that is favorable to accomplishing educational objectives. Because of pragmatism and progressivism – the leading school heads’ educational ideologies – they were able to strike a balance between ideas and uphold a clear, consistent vision for their schools.
Reaction of Grafted Cashew Genotypes to Powdery Mildew Disease in the Western Province of Zambia
Authors: Chisengele L. , Uaciquete A. , Kachapulula P. W.
Published: August 2024

Cashew powdery mildew disease (CPMD), caused by the fungus Pseudoidium anarcadii, has become an economically significant disease of cashew trees in the Western Province of Zambia and many tropical parts of the world. The disease causes significant yield losses of 70 to 100 %. The most effective, sustainable, and environmentally friendly approach to the management of CPMD elsewhere has been through the use of resistant genotypes. Nevertheless, in Zambia, information on the reaction of existing cashew genotypes to CPMD still needs to be discovered. Therefore, this study aimed to evaluate the reaction of cashew genotypes to CPMD in Western Zambia. 90-day-old seedlings from seven cashew genotypes from the ZARI collections were planted and artificially inoculated with cashew powdery mildew spore suspension in a completely randomized design with 15 plant replicates. The experiment was conducted in a screenhouse at Simulumbe Agricultural research station in the Mongu district of Zambia from 20th June to 30th July 2020. Disease incidence and severity were evaluated weekly. Results indicated high variability in the response of the genotypes to powdery mildew disease (P<0.05). Genotype Mab/J/T01 was highly tolerant, while genotype Mab/T117 and Itufa/T01 were moderately tolerant, and genotypes KK/T139 and KK/T65 had low tolerance to CPMD. The rest were highly susceptible. The identified tolerant cashew genotypes are recommended for further direct utilization or incorporation into breeding programs to develop resistant varieties against CPMD in Zambia.
Impact of Outside Blockholders on Related Party Transactions and Book-tax Conformity Link
Authors: Matero Challoner A. , Lee Hsien-Li
Published: August 2024

This study assesses the effects of transfer pricing audit rules in 2005 on related party transactions and book-tax conformity. Further, the presence of outside blockholder beneficially owning at least five percent of the company’s outstanding common stocks is examined. Data from 2003 to 2007 and 2018 of Taiwan-listed firms were collected from the Taiwan Economic Journal database and estimated by ordinary least squares using EViews. This study finds that book-tax conformity has no relation to related party transactions. The presence of outside blockholders is significant in the 2005 sample which might have resulted from an implementation of Transfer Pricing Assessment Rules. However, the presence of outside blockholder as an effective monitor over related party transactions – book-tax conformity link has no evidence. This paper offers evidence in an Asian context to enrich the discussion on related party transactions, book-tax conformity and outside blockholders. The finding is robust to an alternate measure of book-tax conformity.
Plantas macrófitas (Eichhornia crassipes y Pistia stratiotes) como depurador de metales pesados en aguas residuales domésticas
Authors: Lozano-Chung Andi , Lozano-Carranza Carlos Mauricio , Colichon-Carranza Rodrigo David
Published: August 2024

La contaminación por metales pesados en cuerpos de agua es un problema crítico, agravado por el crecimiento urbano y el déficit en saneamiento básico, resultando en vertimientos inadecuados de aguas residuales. Este estudio evaluó la eficiencia de las plantas macrófitas Eichhornia crassipes y Pistia stratiotes para depurar metales pesados en aguas residuales domésticas del río Shilcayo, en el distrito de La Banda de Shilcayo, Perú. Se utilizó una muestra de 120 L de agua residual y 72 plantas durante un período de 6 meses. Se implementaron tres tratamientos de 5, 10 y 15 días, más una muestra testigo. Los resultados mostraron que el tratamiento de 15 días fue el más efectivo, alcanzando una remoción de arsénico del 96,33% con Pistia stratiotes y 96% con Eichhornia crassipes. Ambos tratamientos cumplieron con los estándares del ECA-agua para la categoría de conservación de ambientes acuáticos. Se concluye que el tratamiento de 15 días con Eichhornia crassipes fue el más eficiente en la remoción de plomo y cadmio, alcanzando niveles seguros según las normativas.
Awareness and management of slipping rib syndrome
Authors: Buz Mesut
Published: August 2024

Slipping Rib Syndrome (SRS) is a clinical condition caused by the instability of the costochondral junction, primarily affecting the lower ribs (8th, 9th, and 10th). This syndrome results in severe, often intermittent chest pain due to intercostal nerve entrapment. Diagnosing SRS can be challenging as symptoms often mimic other causes of chest pain. Key clinical features include sharp lower rib pain exacerbated by movement, tenderness on palpation, and pain provoked by the Hooking maneuver. Recent advances in diagnosis and treatment have been highlighted in the literature. Ultrasound has proven effective in confirming SRS diagnosis non-invasively, while surgical interventions offer excellent pain relief, with new diagnostic signs such as reduced rectus abdominis muscle thickness being proposed. Treatment ranges from intercostal nerve blocks and botulinum toxin injections for symptomatic relief to surgical excision of affected costal cartilage for more severe cases. Minimally invasive rib fixation and costal cartilage excision have shown success, providing less invasive options with faster recovery. Continued research and awareness are essential for improving SRS diagnosis and treatment, significantly enhancing patient quality of life.
PENGARUH LIFE STYLE DAN TREND TERHADAP MINAT BELI MINUMAN KOPI YANG DIMEDIASI OLEH PRODUCT KNOWLEDGE (Studi Kasus Pada Pelanggan Cafe/Kedai di Kota Klaten)
Authors: Hadi Abdul , Muhammad Pualam Fadel , Nursito Sarwono , Haris Abdul
Published: August 2024

Abstract
This study aims to investigate the effect of lifestyle and trends on consumer buying interest and the role of product knowledge as a mediator in this relationship. Research uses a quantitative approach to carry out theory testing by using hypotheses and data collection to support or reject the hypothesis. The data was obtained through a survey of respondents who are consumers of coffee drinks. Data collection techniques using a questionnaire. Regression analysis and Sobel's test were used to examine the relationship and mediation between these variables. The estimated parameter value of the estimated regression weight coefficient is 0.209 and the CR value is 1.986 and the probability value is 0.047 (p0.05) this shows that the relationship between Life Style and Purchase Interest. The estimated parameter value of the estimated regression weight coefficient is 0.202 and the CR value is 2.17 and the probability value is 0.030 (p0.05) this shows that there is a trend relationship with buying interest. Based on the results of the Sobel test analysis, it was obtained that the tcount was 2.65901242 > 1.96 with a significance level of 0.047 <0.05 (5%), thus proving that Product Knowledge is a mediating variable on the effect of Life Style on Purchase Intention. Based on the results of the Sobel test analysis, it was obtained that the tcount was 2.64535735 > 1.96 with a significance level of 0.030 <0.05 (5%), thus proving that Product Knowledge is a mediating variable on the influence of Trends on Purchase Interest.
Keyword : Li festyle, consumer buying interest, trend, product knowledge.
Kualitas Laporan Keuangan: Penerapan Akuntansi Sektor Publik Terhadap Akuntabilitas Kinerja Instansi Pemerintah (Studi Kementerian Perhubungan BPTD Kelas II Provinsi Gorontalo)
Authors: Puyo Marten
Published: August 2024

Improving the quality of financial reports can be done by consistently applying public sector accounting standards and conducting regular audits of financial reports. The aim of the research is to determine and analyze the role of the quality of financial reports in moderating the application of public sector accounting reporting standards on the accountability of government agency performance. The research method approach used is a quantitative research method with the type of analysis used is survey analysis, using the PLS-SEM (partial least square modeling) analysis tool. The sample in the research was financial report managers, namely 46 respondents. Based on the results of this research, firstly, the implementation of public sector accounting has a positive and significant effect on the accountability of government agency performance. Second, the quality of financial reports cannot moderate the application of public sector accounting to the accountability of government agency performance. The higher the quality of the financial reports, the greater the possibility that the financial reports can meet the information needs of stakeholders