bluuebunny/crossref_metadata_2025 huggingface dataset:
A Aplicação do Processo de KDD aos Dados da COVID-19: Um Estudo de Caso no Rio Grande do Sul, Brasil
Authors: Heisler Gabriel V. , Assunção Joaquim V. C.
Published: May 2024

Diante da crescente quantidade de dados vinculados a um sistema de saúde complexo, surgem desafios para aprimorar a tomada de decisões com base em padrões de dados. Para enfrentar essa questão, é fundamental explorar a mineração de dados como uma ferramenta para extrair insights valiosos. Este estudo focaliza a aplicação do processo de Descoberta de Conhecimento em Bases de Dados (Knowledge Discovery in Databases – KDD), especialmente nas fases preliminares e de mineração de dados, para identificar padrões nos dados da pandemia de COVID-19 no Rio Grande do Sul, Brasil. Nossas análises revelaram padrões interessantes, como a associação entre sintomas específicos e desfechos dos pacientes. Embora os resultados ofereçam insights valiosos, é importante ressaltar que este estudo não tem a intenção de fornecer conclusões definitivas sobre a relação causal entre os sintomas e os resultados dos pacientes. Em vez disso, busca-se apresentar padrões identificados nos dados, sem interpretar seu significado clínico. Essas descobertas têm o potencial de informar futuras investigações e fornecer uma base sólida para a tomada de decisões proativas em saúde pública.
Lobbyierende Kantone
Authors: Freiburghaus Rahel
Published: May 2024

Not only do interest groups lobby, but regions do too: This book re-examines federalism through the lenses of interest groups and lobbying research. It focuses on ‘shared rule’, a foundational pillar in federal theory that necessitates the active involvement and representation of subnational units in federal policymaking. Based on new and original data, the study illuminates how the 26 Swiss cantons make their voices heard at the federal level. It explores traditional federal institutions, such as second chambers, alongside professionalised tactics of intergovernmental lobbying. Furthermore, the book empirically analyses the conditions under which the cantons succeed in shaping federal policy and politics according to their preferences.
Die Rechtsprechung des EGMR zu häuslicher Gewalt und die Auswirkungen der Istanbul-Konvention
Authors: Woll Laura Katharina
Published: May 2024

The monograph focuses on a critical analysis of the entire body of ECtHR case law on domestic violence against women and its gender-sensitive development over more than 15 years – with both progress and setbacks. The influence as well as the regulatory content of the Istanbul Convention (Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence) are discussed in detail, with a brief comparison of implementation efforts in German and English law. Finally, EU accession to the Istanbul Convention in 2023 is discussed as a milestone in European human rights protection, and the EU’s own legislation in the area of violence against women is examined.
Cytokine-Treated Natural Killer Cells Derived from Cord Blood Haematopoietic Stem Cells Exhibit Potential Cytotoxicity Against Cancer Cells
Authors: Hosseini Fatemeh , Ahmadvand Mohammad , Ai Jafar , Nikbakht Mohsen , Shokouhifar Alireza , Ebrahimi Barough Somayeh , Mousavi Seyed Asadollah , Karimi Roya
Published: May 2024

Background: Despite substantial efforts to leverage natural killer (NK) cells in cancer immunotherapy, challenges associated with limited cell numbers and sources persist. In this study, our objective is to differentiate NK cells from cord blood hematopoietic stem cells (CB-HSCs) and assess their anti-tumor effects. Methods: Cord blood samples were obtained from pregnant women undergoing normal delivery. Mononuclear cells (MNC) were isolated by gradient centrifugation. Subsequently, HSCs were isolated using the MACs cell separation kit. The isolated HSCs were cultured in NK cell differentiation and expansion media for 21 days and 7 days, respectively. The NK cells were examined for expression of activating markers, cytokine secretion and cytolytic effects by flow cytometry, ELISA and XTT tests, respectively. Results: High-purity HSCs and NK cells were obtained in this study. The CB-HSCs-derived NK cells exhibited significantly higher expression of NKG2D, NKp30, NKp44 and NKp46 receptors (at day 28 of treatment) after treatment by IL-15 and IL-2, compared to the early differentiated NK cells (day 21). NK cells derived from CB-HSCs treated with the combination of IL-15 and IL-2 could robustly lyse breast cancer MCF-7 and K562 cells. Also, the obtained NK cells were able to release higher amounts of TNF-α and IFN-γ cytokines in response to tumor cell experiences. Conclusions: Our findings showed that functionally active CB-HSCs-derived NK cells can be successfully generated ex vivo using a cytokine cocktail without a need for stroma for potential use in the cancer immunotherapy.
First Steps in Constructing the KVAD Score to Estimate the Risk of Dehydration in Children with Acute Diarrhea: A Case-Control Study
Authors: Tran Khai Quang , Van Tran Vi , Thao Ly Nguyen , Trung Truong Hieu , Minh Nguyen Phuong
Published: May 2024

Background: Acute diarrhea is a worldwide health concern with a high mortality rate among children under five. Dehydration, a potentially fatal consequence of this illness, must be promptly identified. A scoring system is necessary to predict the degree of dehydration. Objectives: This study aims to identify risk factors and develop a scoring system with an appropriate cutoff to estimate the likelihood of dehydration in children with acute diarrhea. Methods: In this case-control study, the patient group comprised 34 children with acute diarrhea and dehydration, while the control group included 137 children with acute diarrhea without dehydration, admitted to the Gastroenterology Department of Can Tho Children's Hospital, Can Tho city, Vietnam, from November 2022 to October 2023. Results: Acute diarrhea with dehydration was associated with the following factors: Fever (OR 1.802, 95% CI 1.703 - 3.024, P = 0.026), frequency of diarrhea per day (OR 1.744, 95% CI 1.432 - 2.125, P < 0.001), frequency of vomiting per day (OR 1.242, 95% CI 1.102 - 1.399, P < 0.001), and weight-for-age > +2SD (OR 3.293, 95% CI 1.151 - 9.422, P = 0.026). Based on these four parameters and an area under the ROC curve of 0.889, a new scoring system known as the KVAD (K: Kelvin, V: Vomit, A: Avoirdupois, D: Diarrhea) score has been developed. A score of 21 was determined as the optimal cutoff point for identifying dehydration in children with acute diarrhea, with a sensitivity of 79.4% and specificity of 85.4%. Conclusions: The KVAD score represents the initial step in developing an effective and reliable screening tool for estimating the risk of dehydration in children with acute diarrhea.
Cytotoxicity of Fractions of Dracontium spruceanum Chloroform Extract in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines
Authors: Rodriguez-Huamani Arlem , Medina-Calderon Maria , Alvarez-Vega Santiago , Tapia-Rojas Salyoc , Fukusaki-Yoshizawa Alejandro , Mayanga-Herrera Ana
Published: May 2024

Background: Breast cancer is a major health issue responsible for numerous deaths worldwide. Medicinal plants are rich in compounds with potential anticancer properties. Objectives: This study aimed to assess the cytotoxicity of fractions from the Dracontium spruceanum chloroform extract on MDA-MB-231 and MCF-7 breast cancer cell lines. Methods: Eleven fractions were screened for cytotoxic effects on cell viability using the MTT assay. Subsequently, the two most cytotoxic fractions were selected, and the half-maximal inhibitory concentration (IC50) was calculated using two-fold dilution concentrations ranging from 100 to 1.56 µg/mL. Results: Fractions F43 and F50 showed the highest cytotoxicity at 100 µg/mL. The IC50 of F43 was 270.8 ± 18.07 µg/mL and 133.0 ± 17.99 µg/mL for MDA-MB-231, and 252.2 ± 21.94 µg/mL and 144.3 ± 23.14 µg/mL for MCF-7 cells at 24 and 48 hours, respectively. For F50, IC50 values were 107.2 ± 2.97 µg/mL and 126.1 ± 14.77 µg/mL for MDA-MB-231, and 236.4 ± 58.7 µg/mL and 104.5 ± 10.54 µg/mL for MCF-7 at corresponding times. Conclusions: Dracontium spruceanum fractions demonstrated moderate cytotoxicity on MDA-MB-231 and MCF-7 breast cancer cell lines, indicating their anticancer potential. Further research is required to identify the metabolites responsible for this activity and to elucidate the molecular mechanisms involved.
Predicting Sexual Distress Based on Self-compassion in Women with a History of Mastectomy: Investigation of the Mediating Role of Body Image and Difficulties in Emotion Regulation
Authors: Rasouli Maedeh , Khazaie Habibolah , Yarahmadi Yahya
Published: May 2024

Background: The prevalence of sexual distress in women with a history of breast surgery is a critical issue that warrants investigation. Objectives: This study aimed to predict sexual distress in women with a history of breast surgery based on their self-compassion, considering the mediating roles of body image and emotion regulation abilities. Methods: This correlational descriptive study was conducted in 2022 - 2023. The participants comprised 160 patients with a history of breast surgery from Hazrat Rasool Akram, Bazarganan, and Tarbiat Modares hospitals, and Sepid Psychotherapy Clinic in Tehran. A purposive sampling method was employed. Questionnaires were distributed and completed both in-person and online. The instruments used included the Female Sexual Distress Scale-Revised (FSDS-R), Self-Compassion Scale (SCS), Difficulties in Emotion Regulation Scale (DERS), and Body Image Scale (BIS). Data were analyzed using Pearson correlation coefficients and structural equation modeling in SPSS 25 and R software. Results: The research results demonstrated satisfactory model fit. A positive and significant relationship was found between self-compassion and sexual distress, mediated by body image, in participants with a negative history of breast surgery (P < 0.01). Additionally, difficulties in emotion regulation significantly and negatively mediated the relationship between self-compassion and sexual distress (P < 0.01). Conclusions: The findings suggest that self-compassion and difficulties in emotion regulation, with the mediating role of body image, can predict sexual distress in women post-mastectomy. Self-compassion may shield against the impacts of mastectomy by fostering an empathetic and accepting view of oneself. This perspective helps patients adapt more easily to appearance changes, experience fewer emotional difficulties, and endure less sexual distress. Thus, to mitigate sexual problems, psychotherapists are encouraged to employ approaches that emphasize self-compassion, such as acceptance and commitment therapy.
Platelet Indices in Children with Nephrotic Syndrome
Authors: Sadeghi-Bojd Simin , Teimouri Alireza , Zarifi Elham
Published: May 2024

Background: Nephrotic syndrome is a prevalent kidney disease characterized by a significant risk of morbidity. Objectives: The present study aimed to assess the mean platelet volume in children with nephrotic syndrome and controls and compare the groups of patients. Methods: This case-control study was conducted in the pediatric nephrology ward at Zahedan University, Iran, on 491 participants consisting of 333 children with idiopathic nephrotic syndrome and 156 healthy children. Changes in platelet count and mean platelet volume were evaluated in the groups of nephrotic syndrome and healthy children, as well as in steroid-resistant and steroid-responsive patients. Data analysis was performed with SPSS 20 (SPSS, Inc., Chicago, IL). The levels of p-value and confidence coefficient were considered 0.05 and 95%, respectively. Results: The mean platelet count changed significantly in the steroid-responsive, steroid-resistant, and control groups. The mean platelet volume was also significantly different in the steroid-responsive, steroid-resistant, and control groups. In the patients, the mean platelet counts were 413.26 ± 131.81 and 331.26 ± 102.28 (P < 0.001) in those with active phase and remission, respectively. The differences between mean platelet volumes were 8.28 ± 1.22 and 7.96 ± 1.04 (P < 0.001) in those with active phase and remission, respectively. Platelet count and mean platelet volume had no significant correlation with cholesterol, albumin, and protein/creatinine ratio in the patients (r > 0.05). Conclusions: The study concluded that platelet count was highest in the resistant group compared with responders and controls, while the mean platelet volume showed the opposite result. We suggest evaluating these indicators to predict the prognosis of nephrotic syndrome in children.
Teachers’ Competence in Information and Communications Technology
Authors: M. Villegas Elenita , A. Buquia William
Published: May 2024

Teachers' competence in ICT can significantly impact teaching by enhancing instructional methods, increasing student engagement, improving access to information, or facilitating personalized learning experiences. In this context, this study determined the teachers’ level of competence in Information and Communications Technology in Tudela District, Cebu Province Division, located on an island that is the fifth District Municipality in the central Philippines, for the school year 2022-2023. Data for this descriptive study was collected from 60 public school teacher-respondents using a self-made survey questionnaire that has passed the rigorous tests of validity and reliability. The data analysis showed a high level of teachers’ competence in Information and Communications Technology. Teachers' competence in ICT can be enhanced via continued professional growth in the form of suited relevant training and regular school LAC since education is a continuous process for the benefit of the various learners. Through teachers' competence in ICT, DepEd and educational institutions could produce 21st-century learners equipped with life skills that would help our country in boosting our economy; thus, the Philippines benefit and the fulfillment of the new DepEd agenda, which is Matatag: Bansang Makabata, Batang Makabansa.
PENGARUH VARIASI TEMPERATUR HEAT TREATMENT TERHADAP KEMAMPUKERASAN BAJA KOMERSIL DENGAN METODE JOMINY TEST
Authors: Susilo Irwan , Yusuf Yusuf , Ruchiyat Asep
Published: May 2024

Kemampukerasan merupakan kemampuan suatu material untuk dapat dikeraskan sampai kedalaman tertentu dengan cara perlakuan panas hingga terbentuk martensit pada proses pendinginan untuk mencapai kekerasan tertentu. Salah satu metode pengujian hardenability yaitu Jominy Test. Benda uji dipanaskan pada suhu yang ditentukan, kemudian didinginkan dengan menyemprotkan air pada salah satu ujungnya. Setelah pengujian denganalat uji Jominy, diukur kekerasannya dengan menggunakan alat uji kekerasan. Pengujian Jominy dilakukan berdasarkan standard ASTM A255. Pengujian mengunakan spesimen dengan panjang 100 mm, diameter 25,4 mm sebanyak 9 buah. Kekerasan diukur dengan metode Rockwell Hardness Test. Hasil pengujian pada spesimen 1 dengan temperatur akhir 700˚C menghasilkan nilai kekerasan rata-rata 45,51 HRB, pada spesimen 9 dengan temperatur akhir 1100˚C sebesar 47,32 HRB. Semakin tinggi temperatur akhir pemanasan, nilai kekerasan yang dihasilkan akan relatif lebih tinggi. Nilai rata-rata kekerasan tertinggi terdapat pada spesimen 7 dengan temperatur akhir pemanasan 1000˚C sebesar 47,48 HRB.
PENCEGAHAN OVER HEATING MESIN MOBIL HILUX DOUBLE CABIN
Authors: Marjuki Ismael , Epriyandi Epriyandi
Published: May 2024

Kebutuhan manusia yang semakin meningkat pada dunia transportasi khususnya pada kendaraan roda dua atau lebih. Dalam dunia otomotif khususnya mobil dikenal berbagai macam sistem yang bekerja. Sistem-sistem tersebut bekerja saling berkaitan antara satu dengan yang lainnya, sehingga apabila salah satu dari sistem tersebut megengalami kerusakan, maka mobil akan mengalami kerusakan. seperti terjadinya kerusakan pada sistem pendingin yang dapat menyebabkan terjadinya over heating pada mesin. Over heating adalah terjadinya panas yang berlebihan di atas temperatur kerja mesin yang di akibatkan karena terjadinya kerusakan pada salah satu komponen sistem pendingin. Terjadinya over heating pada mesin mobil hilux double cabin disebabkan oleh kurangnya cairan pendingin, thermostat tidak berfungsi dengan baik, tutup radiator bocor, selang inlet dan outlet retak dan water pump rusak. Untuk menghindari terjadinya kerusakan maka harus dilakukan perawatan preventif. Pemeriksaan cairan pendingin pada reservoir radiator setiap 1 minggu dan penggantian cairan setiap 80.000 km. Penggantian thermostat setiap 80.000 km. Penggantian tutup radiator setiap 80.000 km. Penggantian selang inlet dan outlet setiap 80.000 km. Penggantian water pump setiap 80.000 km. dan penggantian v-belt setiap 60.000 km.
Semantics of the Historical Map. Constructing and Using Symbols for Historical Maps
Authors:   Institute of History and Archeology, Ural Branch of the Russian Academy of Sciences Ekaterinburg, Russia, Grishin Evgeniy
Published: May 2024

This article is devoted to the methodological and editorial issues of the formation and use of conventional signs when carrying out historical and cartographic work. It indicates the relevance of historical cartographic semantics, which usually does not receive proper reflection in works on the methodology for preparing historical maps. The author formulates the basic requirements for graphical means of the historical map in relation to their syntax, semantic compliance and general readability; provides the methodological basis for constructing and using symbols. Attention is paid to the structure of historical semantics and its individual blocks. A separate block of the article is devoted to the classification of signs and their areas of application. A description of the symbol resources is given. Sources of replenishment of symbols and mechanisms for the formation of new symbols are given. For each geometric type of symbol, an analysis of the various situations in which it can be used is presented; examples are given that reveal the informational and methodological potential of various techniques for using conventional signs. The article clarifies the concept of a reference base of symbols, which is a set of all available signs, grouped by thematic headings. The methodological provisions of the article are based on the practice of general and thematic mapping, as well as on the author’s personal profes- sional experience. The article is supplemented with examples of the thematic legends design, which can be used as a guide for the further accumulation of a reference base of symbols or for direct use when working with historical maps.
A Microfluidic, Multi-Antibody Cell Capture Method to Evaluate Tumor Cells in Cerebrospinal Fluid in Patients With Suspected Leptomeningeal Metastases
Authors: Sweed Nathan T. , Hsiao Hao-Ching , Blouw Barbara , Pircher Tony J. , Fisher Deanna , Naluz Katrina Rose , Mayer Julie Ann , Dugan Michael C. , Sharma Akanksha , Carrillo Jose , Kesari Santosh
Published: May 2024

Context.—

Leptomeningeal disease (LMD) is a clinical sequela of central nervous system metastasis involving the cerebrospinal fluid (CSF), often seen in late-stage solid tumors. It has a grave prognosis without urgent treatment. Standard of care methodologies to diagnose LMD include CSF cytology, magnetic resonance imaging, and clinical evaluation. These methods offer limited sensitivity and specificity for the evaluation of LMD. Here, we describe the analytic performance characteristics of a microfluidic-based tumor cell enrichment and detection assay optimized to detect epithelial cells in CSF using both contrived samples as well as CSF from patients having suspected or confirmed LMD from carcinomas.

Objective.—

To demonstrate the feasibility of using a microfluidic, multi-antibody cell capture assay to identify and quantify tumor cells in CSF.

Design.—

An artificial CSF solution was spiked with 34 different human carcinoma cell lines at different concentrations and assayed for the ability to detect tumor cells to assess analytic accuracy. Two cell lines were selected to assess linearity, intra-assay precision, interinstrument precision, and sample stability. Clinical verification was performed on 65 CSF specimens from patients. Parameters assessed included the number of tumor cells, coefficient of variation percentage, and percentage of tumor cell capture (TCC).

Results.—

Among contrived samples, average tumor cell capture ranged from 50% to 82% (261 of 522; 436 of 531), and coefficients of variation ranged from 7% to 67%. The cell capture assay demonstrated a sensitivity of 92% and a specificity of 95% among clinical samples.

Conclusions.—

This assay demonstrated the ability to detect and enumerate epithelial cells in contrived and clinical specimens in an accurate and reproducible fashion. The use of cell capture assays in CSF may be useful as a sensitive test for the diagnosis and longitudinal monitoring of LMD from solid tumors.
Frequent Immunohistochemical Expression of Transcriptional Repressor GATA Binding 1 in Salivary Gland Neoplasms: A Sensitive but Nonspecific Marker
Authors: Sriram Sanjay , Kakkar Aanchal , Sarma Chetna , Mahendru Ria , Kumar Rajeev , Kaur Kavneet , Thakar Alok , Deo SVS
Published: May 2024

Context.—

Salivary gland (SG) neoplasms (SGNs) display considerable immunophenotypic diversity. A significant proportion of SG carcinomas develop metastases, with increased diagnostic difficulty at metastatic sites. Transcriptional repressor GATA binding 1 (TRPS1), a novel immunohistochemical marker for breast cancer, has been found to stain certain SGNs.

Objective.—

To investigate TRPS1 and SRY-related HMG-box 10 (SOX10) immunoexpression in various SGNs and non-SG carcinomas, head and neck paragangliomas, and head and neck mucosal melanomas.

Design.—

TRPS1 immunoreactivity score (IRS) was determined as negative or low, intermediate, or high positive; SOX10 was reported as negative or positive.

Results.—

One hundred forty-eight SGNs, 5 breast carcinomas, 105 nonbreast–non-SG carcinomas, including 33 head and neck squamous cell carcinomas (HNSCCs), 6 head and neck paragangliomas, and 6 head and neck mucosal melanomas, were assessed for TRPS1. All 23 benign SGNs showed TRPS1 positivity, with the majority having high-positive IRS (17 of 23 cases; 74%). Among 125 SG carcinomas, 115 of 125 (92%) were TRPS1 positive, with high-positive IRS in 94 of 125 (75%), intermediate-positive IRS in 15 of 125 (12%), and low-positive IRS in 6 of 125 (5%). Among nonbreast–non-SG carcinomas, HNSCC, lung, thyroid, kidney, and ovarian carcinomas showed frequent TRPS1 staining. Nearly half of HNSCCs had high (11 of 18; 33%) or intermediate (4 of 18; 12%) positive IRS. Mean IRS in SG carcinomas was significantly higher than that in nonbreast–non-SG carcinomas (P < .001). None of the TRPS1-positive nonbreast–non-SG carcinomas expressed SOX10.

Conclusions.—

TRPS1 is positive in most benign and malignant SGNs. Its expression in several nonbreast–non-SG carcinomas indicates that it lacks specificity for breast and SG carcinomas, even if considering only high-positive IRS. Addition of SOX10 can increase the discriminatory utility of TRPS1.
Mehmet Emin Rasulzade Düşününde Kafkasya Birliği ve Ermeniler
Authors: Alieva Sevindzh
Published: May 2024

Mehmed Emin Resulzade'nin doğumunun 140. yıl dönümünde, onun ülke tarihindeki rolü ve faaliyetlerine ilişkin sorular yeniden gündeme gelmiştir. Onun Azerbaycan Demoktratik Cumhuriyeti, Ermeniler ve Kafkasya Birliği`ne olan yaklaşımıdaha çok ilgi çeken konulardandır. Özellikle Ermenistan ve Azerbaycan arasındaki ilişkiler, cumhuriyetlerin tanınması, Kafkasya`da Konfederasyon kurgusu meselesinde Ermenilerin eleştirisini görmek mümkündür.Fakat onların eleştirilerinin gerekçesiz olduğunu belirtmek gerekmektedir. Resulzade'yi Nazi Almanyası ile işbirliği yapmakla suçladılar ve bundanbaşka suçlayacak veya eleştirecek bir şey bulamadılar. Böyle asılsız varsayımlar elbette ciddiye alınmamalıdır. Peki Resulzade neden Ermenilerin bu tepkilerine odak noktası olmuştur? Bunun için 20. yüzyıl Azerbaycan tarihine dair önemli bir kaynak olan Mehmed Emin Resulzade'nin kendi eserlerine bakmak gerekmektedir. Eserlerde onun Ermenilere ve Ermeni meselesine ve Kafkasya'nın birleştirilmesine yönelik planlarını görebiliriz. Tüm bu konular çalışmada tartışmaya açılmaktadır.
Formation of Digital Competence of Teachers in Modern Conditions
Authors: Zaripov R. R. , Zaripov A. R. , Symonenko M. Yu.
Published: May 2024

The article addresses the pressing issue of developing digital competence among educators, its role in the educational process, and its impact on learning efficiency in modern conditions. It analyzes key aspects of the digital transformation of education and provides strategies and methods for the effective implementation of digital technologies in the learning process. The article emphasizes the need to consider the rapid development of information technologies and their integration into the educational process to ensure quality training of specialists. It highlights the main obstacles educators face when mastering digital tools and offers ways to overcome them. It points out that digital competence entails not only knowledge of technologies but also the ability to effectively use them to solve tasks and achieve goals in the educational process. This also includes the ability to adapt to changes and use technologies to enhance the quality of education. The article is based on the successful experience of implementing digital tools in the educational process and highlights the key challenges and obstacles faced by Ukrainian educators in wartime conditions. It notes that the development of digital competence results from a combination of knowledge and technological skills, understanding the methodological opportunities offered by technological resources, and attitudes towards using information technologies to transform and improve the quality of education. Implementing information technologies in the educational process makes no sense if the educator does not have a positive attitude towards the benefits and potential these technologies hold. The article is aimed at educational practitioners, researchers, and administrators interested in optimizing the learning process through the use of modern digital technologies and the development of digital skills among educators and students. In conclusion, the authors emphasize the importance of a modern approach to the professional development of educators in the context of the digital transformation of education, as educators need to develop their digital competence to effectively use innovations and technologies.
Unveiling the Nexus: Digital Transformation Leadership, Business Model Innovation, and Performance in China's Banking Sector
Authors:   Centre of Postgraduate Studies, Asia Metropolitan University (AMU), Malaysia., Lyu Wenmin
Published: May 2024

This research investigates the impact of Digital Transformation Leadership on Digital Transformation (DT) performance in China's banking sector. It examines the mediating role of Incremental and Disruptive Business Model Innovation (BMI) and the moderating effect of Data-Driven Insights. Through regression analysis and hypothesis testing, the study confirms positive correlations between DT Leadership and both forms of BMI, as well as their significant contribution to DT performance. Moreover, it identifies the mediating effect of BMI on the relationship between DT Leadership and DT performance. Additionally, Data-Driven Insights are found to positively moderate the relationship between DT Leadership and BMI. These findings highlight the critical role of effective leadership and innovative strategies in driving digital transformation in the banking industry, emphasizing the importance of data-driven decision-making. The study contributes to the existing literature by providing insights into the mechanisms underlying DT in the banking sector, offering practical implications for industry practitioners and policymakers.
Online Shopping Habit Dalam Minat Beli Ulang melalui Marketplace
Authors: Mulyani Sri , Meria Lista
Published: May 2024

Niat beli ulang pelanggan sangat penting untuk profitabilitas dan pertumbuhan berkelanjutan bisnis online. Penelitian ini bertujuan untuk menganalisis pengaruh pada variabel perceived convenience, trust, e-WOM, perceived value, satisfaction terhadap repurchase intention. Penelitian ini mengambil jenis penelitian deskriptif kausalitas dengan pendekatan metode kuantitatif melalui teknik purposive sampling dan didiperoleh 100 responden yang sudah membeli produk pada marketplace Tokopedia dan Shopee lebih dari 3 kali pembelian dalam 1 bulan. Penelitian ini menggunakan metode Structural Equation Model Partial Least Square (SEM-PLS). Hasil penelitian ini menunjukan repurchase intention terbentuk karena dipengaruhi oleh trust dan satisfaction. Selanjutnya, perceived value dipengaruhi oleh perceived convenience, namun perceived convenience, perceived value, e-WOM tidak berpengaruh terhadap repurchase intention. Dengan demikian, penelitian ini dapat menjadi evaluasi evaluasi pada marketplace Tokopedia dan Shopee dalam meningkatkan pengaruh kebiasaan minat beli secara online.
Physicochemical Parameters of Obibia Stream, Amawbia Awka South Local Government Area Anambra State, Nigeria
Authors: Eze H.C. , Obasi C.J. , Ikegwuonu Euphemia Afoma , Enweluzor Adaugo Chinwendu , Chukwujekwu Anulika G. , Okonkwo Ngozi Nonyelum
Published: May 2024

Nigeria has sufficient shallow and deep water, that if polluted can be unhealthy to human life. Obibia stream is an essential water source in Amawbia-Nibo axis of Awka, Anambra State, Nigeria especially for its drinking purposes, urban agricultural usage and domestic uses. Water quality is often altered by anthropogenic activities, leachates and run off. It is therefore necessary to determine the influence of seasonal changes and its effects on the health of populace in this locality. The aim of this study is to evaluate the influence of seasonal changes on the physicochemical parameters of Obibia stream. The statistical analysis was done using ANOVA, Post Hoc Test, Correlation analyses and Paired Test. The physicochemical parameters were within the WHO standard, and the values obtained in the wet season were non-significantly (p>0.05) higher than the values obtained from the dry season, although there was moderate correlation between some selected parameters. The physicochemical parameters were observed to be higher in the wet season than the dry season. Therefore, adequate treatment before use and periodic evaluation of its physicochemical qualities are recommended.
Research on Urban Traffic Management Evaluation-Taking Dhaka City as an Example
Authors: Raihan Prodhan Md Safiq , Biswas Mithun , Mahmudul Hasan Md , Rabbi Mir Fazle , Islam Md Tohidul , Islam Md Rakibul
Published: May 2024

As urbanization continues to accelerate worldwide, efficient traffic management becomes crucial for sustainable urban development. This thesis presents a comprehensive evaluation of urban traffic management in Dhaka City, using it as a case study to analyze the challenges, assess the current strategies, and propose potential solutions for improving traffic flow and reducing congestion. 
Dhaka, the capital city of Bangladesh, is a rapidly growing megacity facing severe traffic congestion and associated problems. This research aims to assess the effectiveness of existing traffic management measures, identify their limitations, and propose evidence-based strategies for enhancing urban mobility. The study adopts a multidimensional approach, integrating quantitative and qualitative methods to evaluate Dhaka's traffic management system holistically. 
The research methodology encompasses collecting and analyzing various data sources, including traffic volume, travel time, road infrastructure, traffic regulations, and public opinion surveys. Additionally, interviews with key stakeholders such as government officials, urban planners, transportation experts, and citizens will be conducted to gather valuable insights into the challenges faced and potential solutions. 
The evaluation will focus on key aspects of urban traffic management, including traffic flow optimization, public transportation efficiency, infrastructure development, and traffic safety. By analyzing the collected data and stakeholder inputs, the study aims to identify the major bottlenecks and deficiencies in the current system, highlighting the underlying causes of traffic congestion in Dhaka. 
Furthermore, this thesis will propose a set of comprehensive recommendations for improving urban traffic management in Dhaka City. These recommendations may encompass infrastructure upgrades, intelligent transportation systems, public transportation enhancements, and policy interventions aimed at reducing private vehicle usage and promoting sustainable modes of transport. 
The findings of this research are expected to provide valuable insights for policymakers, urban planners, and traffic management authorities in Dhaka and other megacities facing similar challenges. By addressing the shortcomings in the existing traffic management system and implementing effective solutions, this study aims to contribute to the sustainable development of Dhaka City and improve the quality of life for its residents.
Performance of Female Entrepreneurs: An Organized Assessment of the Literature Addressing the Factors Affecting Bangladeshi Women Entrepreneurs' Performance
Authors: Gafur Israt , Islam Rafiul
Published: May 2024

With an emphasis on Bangladesh specifically, this research conducts a comprehensive evaluation of the literature on the performance of female entrepreneurs. Although women's contributions to entrepreneurship are becoming acknowledged on a worldwide scale, there are still few systematic evaluations of the variables affecting the success of female entrepreneurs in Bangladesh. Using a thorough examination of peer-reviewed papers, research, and articles, this review pinpoints the major factors influencing the success of Bangladeshi women entrepreneurs. The socio-cultural, economic, institutional, and individual dimensions of these issues provide an all-encompassing view of the opportunities and problems faced by Bangladeshi women in business. The results demonstrate the intricate interactions among cultural norms, financial resource accessibility, the regulatory landscape, and individual traits that influence the performance outcomes of female entrepreneurs. In addition, the assessment points out gaps in the body of knowledge and provides advice for future lines of inquiry that can help women entrepreneurs succeed in Bangladesh and beyond.
Case Study Measurement of the Sustainability Performance of Indian Pulses Firms via Performance Measurement and Management System and Balanced Scorecard Method
Authors: Sahu Mandavi , Bayana Sanjay
Published: May 2024

The sustainable performance of production and operation processes of all pulse processing firms to generate efficient pulse processing processes. The case study adopted the balanced scorecard method (SCORE) and performance measurement and management system (P.M.M.S.) technique, which has performed on sustainability indicators on different production and operation parts of selected pulses firms. The pulse firms are selected from the following states are Uttar Pradesh, Rajasthan, and Delhi /NCR regions. The analysis of sustainability factors determines the current status of pulse processing firms and describes each risk factors that affect the performance of pulse processing firms. The study considers all internal and external factors of the manufacturing process with a sustainability dimension are applies with quantitative analysis techniques to achieve the production and operation at optimum levels. The case study describes the performance measurement and management systems techniques and balances scorecard method, which generates Information to develop strategic decision-making, and also develops the key performance indicators to analyze the firms' financial and nonfinancial measures. The case study developed the conceptual model framework structure of PMMS and balanced scorecard method, that firms are implementing the score techniques at different levels and explains their process in an organization, also measuring the sustainability performance of firms. The case study analyses the various significant levels of risk, which made the direct impact on the sustainability performance of all selected pulse firms and define the current status of pulse firms also discussed the implementation of pulse value chain practices. The case study generates the relevant Information which is applied for decision-making, also reduces the major constraint of all pulse’s firms.
Analyzing the Impact of Heat and Mass Transfer on Unsteady MHD Flow with Thermal Radiation and Binary Chemical Reaction
Authors: Ometan Sunday O. , Alabi Mathew O. , Okedoye Akindele M.
Published: May 2024

In this paper, we investigate the combined effects of heat and masstransfer on unsteady oscillatory magnetohydrodynamic (MHD) flow withthermal radiation and binary chemical reaction. The governing equationsof the flow field, energy equation, and species concentration equation arederived under the assumptions of incompressible flow, uniform magneticfield, and small amplitude oscillations. The influence of thermal radiation and chemical reaction is incorporated through appropriate boundary conditions. Mathematical formulations are presented for the coupled systemof equations, and numerical simulations are conducted to analyze the heatand mass transfer characteristics of the flow. Sensitivity analysis of the governing parameters were conducted and presented through graphs and discussed. The results provide insightsinto the complex interplay between fluid dynamics, thermal radiation, andchemical reaction in MHD systems and their implications for engineeringapplications.
Effect of Time Delay in the Stability Analysis of Cholera Epidemic-Endemic Disease Model
Authors: Chukwumela Adiela , Iyai Davies
Published: May 2024

Cholera as a disease is a kind of acute diarrhea caused by bacteria Vibrio cholerae. A nonlinear delayed mathematical model with environmental factor for the spread of infectious disease cholera is proposed and analyzed. A mathematical model for cholera was improved by adding a time delay that represents the time between the instant at which an individual becomes infected and the instant at which he begins to have symptoms of cholera disease. It is assumed that all susceptible are affected by carrier population density. The model is analyzed by stability theory of differential equations and computer simulation. We prove that the delayed cholera model is biologically meaningful and analyze the local asymptotic stability of the equilibrium points for positive time delays. Both the disease-free (DFE) and endemic equilibria are found and their stability investigated using the Routh-Hurwitz stability criterion method. Next Generation Matrix (NGM) method was used to get the basic reproductive number
Open source in drug discovery
Authors: Willighagen Egon
Published: May 2024

Geldenhuys et al. published an article in Drug Discovery Today titled

Optimizing the use of open-source software applications in drug discovery

(DOI:10.1016/S1359-6446(05)03692-5), and approached the review from a bench chemist point of view.
How to make money from Open Source scientific software
Authors: Willighagen Egon
Published: May 2024

Dan (the original Jmol author) has an interesting blog series: How to make money from Open Source scientific software I, II and III. Three more blog items are in the planning. The deal with how to make money from open source scientific software. He wants to be able to skeptically review the software in his field, hence open source.
Molybdenum mitigates cadmium stress for bread wheat (Triticum aestivum L.) seedlings
Authors: Magid Khalid , Al-Issawi Mohammed
Published: May 2024

Pollution with heavy metals has become a serious problem that threatens all living organisms. Cadmium (Cd) pollution has become focus of the environmental studies and can negatively affect human health and plant growth. Molybdenum has been highlighted as a stress resistant micronutrient that supports the defense system against environmental stresses. In this context, this study highlighted the role of molybdenum in the mitigation of the toxic effect of cadmium in wheat seedlings. The study included four concentrations of cadmium (0, 75, 150, and 225 mg L-1 ), three concentrations of molybdenum (0, 15, and 30 mg L-1 ), and two wheat genotypes (G-31 and IRAQ). These factors were laid as a factorial experiment according to a completely randomized design (CRD) with three replications. The results of this study indicated the negative impact of cadmium on wheat seedlings' growth in terms of physiological and anatomical traits. It also highlighted the positive role of molybdenum in the mitigation of the toxic effect of cadmium. Molybdenum at a concentration of 15 mg L-1 enhanced the structure of the root and leaf of cadmium treated wheat. The two wheat genotypes did not vary in terms of anatomy when they were treated with molybdenum. Further studies are required on a wide range of wheat genotypes to investigate their ability to withstand heavy metal stress. Therefore, heavy metal-tolerant genotypes could be utilized in heavy metal-contaminated soils.
Investigating the effect of consumer xenocentrism on purchase intention for foreign products
Authors: Hall Elif , Şeyh Bilecik , Najmaldın Gulhan , Karamasa Caglar
Published: May 2024

Background: Broadly defined as preference for another country rather than your own, xenocentrism in the context of consumer and consumption refers to willingness to purchase foreign products even if there are equivalent domestic products that are similar or even better in quality. Purpose: The aim of this study is to determine the effect of consumer xenocentrism on Iraq-Kirkukian consumers' purchase intention for Turkish products. In addition, the study also examines the differences between the demographic variables and xenocentrism. Study design/methodology/approach: To achieve these purposes, a survey was administered to a sampling consisting of 450 individuals selected by using convenient sampling method, and 418 of these surveys were included in the analyses. This sampling consisted of Turkmens, Arabs and Kurds. T-test and ANOVA test were performed to identify the differences between demographic information about the participants and xenocentrism. Factor analysis was done for the scales used in the study, and multiple regression analysis was done later to obtain the effect of consumer xenocentrism on purchase intention for Turkish products. Findings/conclusions: The results of the study reported a positive and significant effect of consumer xenocentrism on purchase intention for Turkish products. In addition, consumer xenocentrism in Kirkukian consumers did not differ according to gender and ethnic identity. Limitations/future research: The research was conducted in the city of Kirkuk, Iraq, which was under adverse political and security conditions and face-to-face survey was limited. The results cannot be generalized since Kirkuk has the most diverse ethnic identity in Iraq and is a place where Turkmens live more densely than other cities. Therefore, conducting this research in other countries would yield different results. In particular, examining the structure of consumer xenocentrism in developed economies would provide additional information about the prevalence and impact of xenocentric tendencies in these countries. It is also important to investigate the impact of consumer xenocentrism on other variables such as product decisions, risk perceptions and willingness to pay.
Examining shared leadership dimensions through a social network approach: A case from tourism industry
Authors: Asbas Caner , Tuzlukaya Sule , Maaroof Aymen
Published: May 2024

Background: Shared leadership is regarded as a fundamental approach to complexity leadership theory in terms of adaptability and flexibility. It emerges from communication among team members in a complex environment and consists of three dimensions: task coordination, personal support, and information sharing. Purpose: This study investigates shared leadership and its dimensions which are task coordination, personal support, and information sharing using social network analysis. By incorporating social network theory, the social and relational aspects of shared leadership can be revealed and emphasized. Study design/methodology/approach: Social network analysis was used to test the hypotheses on the data collected from the employees of a tourism organization. Findings/conclusions: The findings indicate that the individuals in task coordination, personal support and information sharing networks have a medium or low percentage of degree centrality in the social networks of their units or departments. The social networks of task coordination, personal support and information sharing have a high percentage of degree density when all individuals are treated as a total network and individuals in different departments and units as separate networks. This situation is led by the more balanced distribution of the power among the actors, dense communication between the members and intense network relations in task coordination, personal support and information sharing networks. Limitations/future research: The present study focuses only on internal network relations. As a future body of work, the study could be expanded to include both external and internal network relations to provide a wider understanding of the shared leadership concept. As another future body of work, to reach more generalizable results, this study can be expanded with a meta-analysis that will be performed on the results obtained by applying the survey on other organizations and processing the data collected with social network analysis methods again.
Evaluating automobile’s vibration in frequency domain
Authors: Jia Yujie , Nguyen Vanliem
Published: May 2024

Excitation of the low frequency not only influences the driver’s health but also strongly affects the durability of the automobile’s structures. To research the automobile’s vibration in the low-frequency region, a dynamic model of the automobile is established to calculate the vibration equations of the automobile in the time region. Based on the theory of the Laplace transfer function, the automobile’s vibration equations in the time region are transformed and converted to the automobile’s vibration equations in the frequency region. Then, the effect of the automobile’s design parameters and operation parameters on the characteristic of the automobile’s acceleration-frequency is simulated and analyzed to evaluate the automobile’s comfort as well as the durability of the automobile’s structures in the frequency region. The research results show that the design parameters of stiffness, mass, and road wavelength remarkably affect the characteristic of the automobile’s acceleration frequency. To reduce the resonant amplitude of the acceleration frequency in the vertical and pitching directions of the automobile, the stiffness parameters of the automobiles and tires should be reduced while the mass of the automobile’s body should be increased. Additionally, the road’s roughness also needs to be decreased, or the road’s quality needs to be enhanced to reduce the resonant amplitude of the automobile’s acceleration frequency.