bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrated Neutrosophic Best-Worst Method for Comprehensive Analysis and Ranking of Flood Risks: A Case Study Approach from Aswan, Egypt
Authors: Al-Saeed Safa , AbdelAziz Nabil M.
Published: September 2023

This paper presents a comprehensive framework for the analysis and ranking of flood risks with respect to regional variations and data uncertainties under a Neutrosophic environment. The research introduces a novel approach to flood risk mitigation and management, bringing together the scientifically robust Best-Worst Method (BWM) and single-valued Neutrosophic set for the first time. The unique application of a single-valued Neutrosophic set allows us to better illustrate and manage uncertainty, imprecision, and vagueness in data. Additionally, we employ BWM, a multi-factor decision-making method, for discerning and ranking the most influential flood risk factors. Together, the integrated methodologies provide a balanced, comprehensive guide for decision-makers and risk handlers, showcasing efficient and effective mitigation strategies. The paper emphasizes the importance of mitigating flood risks to save lives and properties and to manage and conserve environmental resources efficiently. A case study was conducted in Aswan, Egypt, to assess flood susceptibility. The results revealed that 12.60% of the study area exhibited very high susceptibility to flooding, 18.77% showed high susceptibility, 23.94% exhibited moderate susceptibility, 22.91% registered a low susceptibility, and the remaining 21.78% showed very low susceptibility to flooding.
An Investigative Study on Quick Switching System using Fuzzy and Neutrosophic Poisson Distribution
Authors: G Uma , S Nandhitha
Published: September 2023

Stephens and Larson (1967) stated the sampling system as an allotted grouping of two or three sampling plans and the rules for switching between the plans for sentencing the lots of manufactured products. Quick Switching System (QSS) by Romboski (1969) is a sampling system with reference to the Single Sampling Plan (SSP) involves normal and tightened plans by adopting a switching rule. QSS provides quality protection and a reduction in the cost of inspection. The idea of fuzzy logic is adopted in the system to handle situations of fraction non-confirmation, uncertainty, or vagueness present in the parameters. The sampling plans based on fuzzy set theory in the literature are used for the defuzzification of fuzzy numbers into interval sets, able to solve problems with certain values for the upper and lower limits of intervals. As one of the expansions of fuzzy sets in this era, a new philosophy is stimulated as a substantial new theoretical development: neutroosophy sets (NSs) and used for a rise in sensitiveness that makes flexibility in the plans and systems that can be applied in the manufacturing industries. This paper enhances the determination of QSS using Neutrosophic Poisson distribution and compares it with the existing fuzzy Poisson distribution through Operating Characteristic (OC) curves.
A Perspective Note on μ_N σ Baire’s Space
Authors: Ben N. Raksha , Annam G. Hari Siva , Rajapushpam G. Helen
Published: September 2023

This paper presents an introduction to many novel types of sets, including μN strongly dense sets, μN strongly nowhere dense sets, μN strongly first category sets, and μN strongly nowhere residual sets. The features of these sets are briefly elucidated. In addition, by the use of these techniques, we have successfully obtained the highly Baire space μN, and it is imperative to elucidate its inherent features.
BER Analysis of BPSK Modulation Scheme for Multiple Combining Schemes over Flat Fading Channel
Authors: Nishtar Zuhaib , Afzal Jamil
Published: September 2023

Focus of the study was to provide error-free communication in mobile communication with higher data rates, spectral efficiency, and energy efficient. Basically, work was done to investigate the performance of the Binary Phase Shift Keying (BPSK) modulation technique for multiple combining schemes and the behavior of signal in wireless communication where multipath propagation and uncertainty in the system. We use the Multiple-input Multiple-output (MIMO) and antenna diversity to get many copies of the same signal; some of them were faded, but some had sufficient information. Then the next step was to combine or select the best signal to achieve the optimum results from them. Moreover, the Bit Error Rate (BER) of multiple combining schemes for 2*1 and 2*2 were found and the results of each combining scheme were compared. Later on, the comparison of these combining schemes was collectively represented; it is very important because getting the required data from the received copies of the same signal is not easy.
Energy Efficiency and Material Cost Savings by Evolution of Solar Panels Used in Photovoltaic Systems under Neutrosophic Model
Authors: Sleem Ahmed , Elhenawy Ibrahim
Published: September 2023

Traditional applications of solar panels have been limited to smaller-scale energy production, such as that required by single houses or apartment complexes. Researchers from all around the globe have been working together to develop creative, efficient goods, increase the energy efficiency of solar panels, and build new, ground-breaking practices using photovoltaic system design. Solar photovoltaic (PV) system planning demands a strategic decision-making approach to socioeconomic growth in many nations due to the rising understanding of the financial, social, and ecological aspects. The primary goal of this study is to provide a novel, adaptable method of Multi-Criteria Decision Making (MCDM) for government decision-makers (DMs) to use in evaluating solar PV panel manufacturers using various variables. This paper used the single-valued neutrosophic set to deal with the vague data. The neutrosophic set is used with the Characteristic Objects Method (COMET). The COMET method is an MCDM method. It is used to compute the rank of alternatives. The application of the proposed method is introduced with eleven criteria and ten solar panels in PV.
Mitigating Landslide Hazards in Qena Governorate of Egypt: A GIS-based Neutrosophic PAPRIKA Approach
Authors: AbdelAziz Nabil M. , Al-Saeed Safa
Published: September 2023

This paper presents a novel approach to landslide susceptibility assessment in the Qena Governorate, Egypt, integrating the neutrosophic Multi-Criteria Decision-Making (MCDM) method, the Potentially All Pairwise RanKings of all possible Alternatives (PAPRIKA), and the ArcGIS weighted overlay technique. The research focuses on the quantification and prioritization of eight criteria: slope, aspect, proximity to road, soil type, proximity to river, land cover, elevation, and Lithology. These factors are evaluated under the uncertainty and indeterminacy of the neutrosophic environment by employing the PAPRIKA method. The results of the analysis are visualized and interpreted using ArcGIS weighted overlay, offering spatially explicit insights into the landslide-prone areas. This study's outcomes could significantly contribute to the overall understanding of landslide hazards in Qena, promoting better hazard management and mitigation strategies. The results of the study demonstrated varying levels of landslide susceptibility within the study area: 2% of the area was identified as having Very High Susceptibility, 17% presented High Susceptibility, 28% had Moderate Susceptibility, 44% indicated Low Susceptibility, 8% showed Very Low Susceptibility, and 1% with Practically No Susceptibility. These findings can aid local authorities and policy-makers in prioritizing areas for mitigation efforts based on their susceptibility to landslides. The study also incorporates a sensitivity analysis, exploring ten different scenarios to ensure the robustness and reliability of the results. In the first scenario, we adhere to our initial criteria weights to represent the current situation. In the second scenario, all criteria are accorded equal significance to check the model's steadfastness when no one criterion outweighs another. Scenarios three to ten each elevate the weightage of one criterion, allowing for a comprehensive understanding of each individual criterion’s influence on the decision-making process. This systematic alteration helps pinpoint the salient features driving landslides and aids in fortifying our mitigation strategies.
Neutrosophic gsα* - Open and Closed Maps in Neutrosophic Topological Spaces
Authors: Rodrigo P. Anbarasi , Maheswari S.
Published: September 2023

The main aim of this paper is to introduce a new concept of Neu-mapping namely Neugsa*-open maps and Neugsa* -closed maps in Neu-topological spaces. Additionally, we relate the properties and characterizations of these mappings with the other mappings in Neu-topological spaces.
Generalized Double Statistical Convergence Sequences on Ideals in Neutrosophic Normed Spaces
Authors: M. Jeyaraman , S. Iswariya , R. Pandiselvi
Published: September 2023

In this present research, having view in the Neutrosophic norm (u, v, w), which we presented I2-lacunary statistical convergence and I2-lacunary convergence strongly, looked into interactions between them, and made a few findings regarding the respective categories. At least went further to look at how both of such case approaches relate to I2-statistical convergence within the relevant Neutrosophic normed space.
Toward a Minor Tech
Authors: Andersen Christian Ulrik , Cox Geoff
Published: September 2023

This journal issue addresses what we are calling "minor tech" making reference to Gilles Deleuze and Félix Guattari's essay "Kafka: Toward a Minor Literature" (written in 1975). They propose the concept of minor literature as opposed to great or established literature — the use of a major language that subverts it from within. "Becoming-minitorian" in this sense — to use a related concept from A Thousand Plateaus — involves the recognition of particular instances of power and the ability of the repressed minority to gain some degree of autonomy of expression. For our purpose, this notion of the minor is a relative position to major (or big) tech.
Glitchy, Caring, Tactical
Authors: Kir Freja
Published: September 2023

This paper directs attention to the parameters of creative resistance to large-scale commercial digital platforms. It does so by enhancing the understanding of minor tech through the analysis and case study of the artwork, VPN. While minor tech might sound unfamiliar to the many, examples of its existence are at the same time incredibly familiar through examples of digital commoning, sharing of skills, and organisational systems. In the case of VPN, the work existed as a growing emancipatory multimedia archive, executed as a transparent server architecture revealing its technical workings to its users. This format exemplified tactics of intentional glitches through an artful inclusion of persons, space, and objects. By identifying the elements of tactics and care within the VPN, the paper draws parallels of overlapping tendencies within the movement of minor tech. Drawing on Olga Gorionova's research on 'Shadow librarians' and including former digital examples of knowledge sharing furthermore assists in sketching a web development towards the nature of minor tech and VPN. By analysing the significance of these initiatives, the paper raises the questions: What are the drives across creative resistance practices? And (how) do such creative contributions help to critically nuance various existing understandings of large-scale digital platforms?
A Range Space with Constant VC Dimension for All-pairs Shortest Paths in Graphs
Authors: De Lima Alane , Da Silva Murilo , Vignatti André
Published: September 2023

Let $G$ be an undirected graph with non-negative edge weights and let $S$ be a subset of its shortest paths such that, for every pair $(u,v)$ of distinct vertices, $S$ contains exactly one shortest path between $u$ and $v$. In this paper we define a range space associated with $S$ and prove that its VC dimension is 2. As a consequence, we show a bound for the number of shortest paths trees required to be sampled in order to solve a relaxed version of the All-pairs Shortest Paths problem (APSP) in $G$. In this version of the problem we are interested in computing all shortest paths with a certain "importance"
at least $\varepsilon$. Given any $0 < \varepsilon$, $ \delta < 1$, we propose a $\mathcal{O}(m + n \log n + (\textrm{diam}_{V(G)})^2)$ sampling algorithm that outputs with probability $1 - \delta$ the (exact) distance and the shortest path between every pair of vertices $(u, v)$ that appears as subpath of at least a proportion $\varepsilon$ of all shortest paths in the set $S$, where $\textrm{diam}_{V(G)}$ is the vertex-diameter of $G$. The bound that we obtain for the sample size depends only on $\varepsilon$ and $\delta$, and do not depend on the size of the graph.
Relevé du territoire : les souverainetés alimentaires autochtones1
Authors: Daigle Michelle
Published: September 2023

La recherche dans le domaine de la souveraineté alimentaire vit actuellement un renouveau conceptuel qui vise à rendre compte des diverses expressions de la souveraineté telle qu’elle s’incarne dans l’espace en fonction des spécificités historiques et identitaires, et des situations et dynamiques socioécologiques locales. Les efforts pour en identifier les nombreuses assises ont permis d’attirer l’attention sur les enjeux particuliers de la souveraineté alimentaire autochtone en Amérique du Nord. Notamment, les spécialistes s’intéressent aujourd’hui aux liens qui unissent la régénération des pratiques de récolte et de partage des aliments avec les mouvements pour l’autodétermination et la décolonisation. Si on ne peut que se réjouir de ce nouvel intérêt, il reste toutefois beaucoup de travail à faire pour comprendre comment les multiples ordres et autorités autochtones en matière juridique et politique s’expriment au quotidien dans la pluralité des souverainetés alimentaires et des environnements. Dans cette contribution, je m’intéresse aux Anishinaabe vivant tant à l’intérieur qu’au-delà des limites du territoire couvert par le Traité no 3 (Ontario, Canada) : je veux mettre en lumière les actes de résurgence quotidiens, basés sur le principe du mino bimaadiziwin, avec lesquels ils protègent et revitalisent leurs terrains de récolte alimentaire, leurs eaux et leurs modes d’alimentation.
L’accès à la saine alimentation dans l’est de l’île de Montréal : entre alignements et discordances
Authors: Audet René , Brisebois Éliane , Lefèvre Sylvain A. , Mercille Geneviève , Gallani Alessandra , Verville-Légaré Marjolaine
Published: September 2023

Face aux enjeux spatiaux et économiques d’accès à la saine alimentation dans l’est de l’île de Montréal, des instances de santé publique, des organisations communautaires et leurs partenaires ont mis sur pied le Réseau alimentaire de l’est de Montréal (RAEM) afin de mieux coordonner les interventions auprès des ménages à faible revenu (MFR). Ces interventions s’inscrivent notamment dans une perspective spatiale de l’accès à l’alimentation et dans des modèles qui diffèrent de ceux de l’aide alimentaire classique. Dans le cadre d’une recherche partenariale menée avec le RAEM visant à déterminer les points d’alignement et de discordance dans les représentations du problème d’accès alimentaire et les solutions privilégiées de trois types d’acteurs (les organisations membres du RAEM, les partenaires de soutien et les MFR), nous avons effectué une collecte de données par l’entremise de groupes d’entretien et d’entretiens individuels. L’analyse des données, réalisée à partir d’un modèle multidimensionnel de l’accès à la saine alimentation, permet de comparer les perspectives de chaque groupe d’acteurs. Il en ressort que la dimension spatiale n’est pas aussi centrale pour les MFR que pour les autres acteurs, et que la dimension personnelle de l’accès est perçue différemment selon les acteurs. Ces discordances ont une importance et un impact pour l’organisation du système alimentaire de l’est de l’île de Montréal, et mettent en lumière la nécessité d’une lecture critique d’un cadrage principalement spatial des problèmes d’accès à l’alimentation.
Les frigos collectifs
Authors: Bherer Laurence , Lelièvre Agathe
Published: September 2023

Cet article rend compte de l’émergence d’une pratique discrète de gestion des surplus alimentaires : le stockage et la redistribution depuis les frigos collectifs. Pour ce faire, il s’appuie sur une enquête ethnographique conduite entre 2016 et 2020 dans les villes de Montréal et de Québec. Il montre que ces pratiques s’insèrent dans les interstices du circuit classique de redistribution alimentaire pour proposer une gestion alternative des surplus. Les frigos n’opèrent toutefois pas en rupture avec le modèle des banques alimentaires mais plutôt en complémentarité, car ils offrent, à plus petite échelle, une avenue de plus pour disposer des surplus produits par l’industrie alimentaire. Aussi, c’est surtout dans le rapport aux donataires que les frigos apparaissent s’inscrire dans une pratique alternative. Avec le temps, ces frigos se révèlent néanmoins fragiles et tendent à disparaître ou à se formaliser.
Démocratie alimentaire et approches sensibles dans la transition écologique
Authors: Granchamp Laurence , Lamine Claire , Berthomé Guy El Karim , Tuscano Martina , Jenatton Morgan
Published: September 2023

Cet article interroge la place accordée aux dimensions sensibles (au sens d’attachement, de ce qui « fait sens », ce à quoi l’on tient) ainsi que leur rôle au sein des dispositifs et expérimentations qui visent la transition écologique dans et par les systèmes alimentaires, à travers six cas situés dans différentes régions de France. Plus précisément, il sonde ces attachements afin de voir ce qu’ils peuvent apporter à la participation de publics à première vue éloignés des enjeux de transition écologique, et en explore la portée en matière de politisation. Il montre que la prise en compte de ces attachements offre un contrepoint aux approches technicistes et normatives de la transition écologique, tout en permettant de traiter les enjeux de la démocratie et de la justice alimentaires. Il identifie trois voies de politisation, diversement combinées dans les six expérimentations étudiées : la capacitation/l’augmentation du pouvoir d’agir (empowerment), la valorisation des pratiques et/ou des savoirs, et la formation de collectifs. Il suggère, enfin, qu’en dépit des limites que nous identifions, la prise en compte de ces dimensions sensibles favorise, sous certaines conditions, l’inclusion et la participation de ces publics. Cette prise en compte offre en outre une voie privilégiée pour l’articulation des enjeux de justice et de démocratie alimentaires aux enjeux environnementaux, ce qui mériterait d’être davantage considéré ou du moins discuté dans le cadre des politiques de transition écologique.
Lecturas de verano en torno al periodismo y la desinformación
Authors: Fecé Josep Lluís
Published: September 2023

Las últimas elecciones en el Congreso de los Diputados giraron en gran medida en torno a la mentira y las falsedades en las que incurrían los candidatos y las candidatas al Gobierno. La campaña estuvo más centrada en la oposición verdad/mentira que en la explicación de los programas o de las políticas públicas de los partidos. Al mismo tiempo, una de las principales tareas de los medios de comunicación –conservadores o progresistas– ha sido la verificación. En la mayoría de los casos, la comprobación no servía para aportar conocimiento sobre una afirmación o un hecho, sino para posicionarse a favor o en contra de la persona candidata.
Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
Authors: Chan Alex W , Broncel Malgorzata , Yifrach Eden , Haseley Nicole , Chakladar Sundeep , Andree Elena , Herneisen Alice L , Shortt Emily , Treeck Moritz , Lourido Sebastian
Published: September 2023

Apicomplexan parasites use Ca 2+ -regulated exocytosis to secrete essential virulence factors from specialized organelles called micronemes. Ca 2+ -dependent protein kinases (CDPKs) are required for microneme exocytosis; however, the molecular events that regulate trafficking and fusion of micronemes with the plasma membrane remain unresolved. Here, we combine sub-minute resolution phosphoproteomics and bio-orthogonal labeling of kinase substrates in Toxoplasma gondii to identify 163 proteins phosphorylated in a CDPK1-dependent manner. In addition to known regulators of secretion, we identify uncharacterized targets with predicted functions across signaling, gene expression, trafficking, metabolism, and ion homeostasis. One of the CDPK1 targets is a putative HOOK activating adaptor. In other eukaryotes, HOOK homologs form the FHF complex with FTS and FHIP to activate dynein-mediated trafficking of endosomes along microtubules. We show the FHF complex is partially conserved in T. gondii , consisting of HOOK, an FTS homolog, and two parasite-specific proteins (TGGT1_306920 and TGGT1_316650). CDPK1 kinase activity and HOOK are required for the rapid apical trafficking of micronemes as parasites initiate motility. Moreover, parasites lacking HOOK or FTS display impaired microneme protein secretion, leading to a block in the invasion of host cells. Taken together, our work provides a comprehensive catalog of CDPK1 targets and reveals how vesicular trafficking has been tuned to support a parasitic lifestyle.
Body size and trophic level increase with latitude, and decrease in the deep-sea and Antarctica, for marine fish species
Authors: Lin Han-Yang , Costello Mark John
Published: September 2023

The functional traits of species depend both on species’ evolutionary characteristics and their local environmental conditions and opportunities. The temperature-size rule (TSR), gill-oxygen limitation theory (GOLT), and temperature constraint hypothesis (TCH) have been proposed to explain the gradients of body size and trophic level of marine species. However, how functional traits vary both with latitude and depth have not been quantified at a global scale for any marine taxon. We compared the latitudinal gradients of trophic level and maximum body size of 5,619 marine fish from modelled species ranges, based on (1) three body size ranges, <30, 30–100, and >100 cm, and (2) four trophic levels, <2.20, 2.20–2.80, 2.81–3.70, >3.70. These were parsed into 5° latitudinal intervals in four depth zones: whole water column, 0–200, 201–1,000, and 1,001–6,000 m. We described the relationship between latitudinal gradients of functional traits and salinity, sea surface and near seabed temperatures, and dissolved oxygen. We found mean body sizes and mean trophic levels of marine fish were smaller and lower in the warmer latitudes, and larger and higher respectively in the high latitudes except for the Southern Ocean (Antarctica). Fish species with trophic levels ≤2.80 were dominant in warmer and absent in colder environments. We attribute these differences in body size and trophic level between polar regions to the greater environmental heterogeneity of the Arctic compared to Antarctica. We suggest that fish species’ mean maximum body size declined with depth because of decreased dissolved oxygen. These results support the TSR, GOLT and TCH hypotheses respectively. Thus, at the global scale, temperature and oxygen are primary factors affecting marine fishes’ biogeography and biological traits.
Temporal variation of the relationships between rice yield and climate variables since 1925
Authors: Chen Hungyen , Wu Yi-Chien , Teng Chih-Yung
Published: September 2023

Background

Long-term time-series datasets of crop yield and climate variables are necessary to study the temporal variation of climate effects on crops. The aim of this study was to broadly assess assessment of the effects of climate on rice, and the associated temporal variations of the effects during the long-term period.

Methods

We conducted field experiments in Taiwan from 1925 to 2019 to collect and analyze rice yield data and evaluate the impacts of changes in average temperature, diurnal temperature range (DTR), rainfall, and sunshine duration on rice yield during cool and warm cropping seasons. We then estimated the relationships between annual grain yield and the climate variables using the time series of their first difference values. We also computed the total relative and annual actual yield changes using regression coefficients for each climate variable for the intervals 1925–1944, 1945–1983, and 1996–2019 to reveal the impacts of climate change on yields and the associated temporal variations during the overall experimental period.

Results

The annual daily average temperature calculated from the trend of the regression lines increased by 0.94–1.03 °C during the 95-year period. The maximum temperature remained steady while the minimum temperature increased, leading to decreased DTR. The total annual rainfall decreased by 237–352 mm and the annual total sunshine duration decreased by 93.9–238.9 h during the experimental period. We observed that during the cool cropping season, yield response to temperature change decreased, while that to DTR and rainfall changes increased. During the warm cropping season, all the yield responses to temperature, DTR, and rainfall changes were negative throughout the experimental period. In recent years (1996–2019) the estimated annual actual rice yield changes during the cool cropping season were negatively affected by climate variables (except for sunshine duration), and slightly positively affected (except for temperature) during the warm cropping season. Compared to the effects of temperature and DTR, those of rainfall and sunshine duration on rice yield changes were weak. This study contributes to provide impacts of climate change on rice yield and associated long-term temporal variations over nearly a century.
Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
Authors: Singhal Ridhima , Yadav Anjali , Tewari Shikha , Tanwar Nishi , Devi Anju
Published: September 2023

Squamous Cell Papilloma (SCP) is a benign, asymptomatic, exophytic cauliflower-like growth of mucosal mass. It is mostly associated with Human Papilloma Virus (HPV) subtypes 6 and 11, and has a very low virulence and infectivity rate. The papillomas are commonly known as warts or verrucas when found on the skin. The typical lesion is a single mass with finger-like extensions, resembling a soft, pedunculated growth supported by a stem or stalk. If keratin, a skin protein, accumulates around the lesion, the projections can be long and pointed or short and rounded. Intraorally, the most common sites of occurrence are the tongue, lips, buccal mucosa, palate, and uvula. Hereby, the author present a case report of 25-year-old male patient with a 4x9 mm exophytic growth exhibiting a pebbled surface in the upper left first premolar region, with no signs of radiographic bone loss. Additionally, smaller pinpoint lesions were observed bilaterally in the interdental region of the first and second maxillary molars. A nevus on the right side of the face was also noted. Histological analysis confirmed the diagnosis of SCP. The presence of multifocal gingival squamous papilloma, along with an extraoral nevus, represents a novel finding that warrants reporting. The gingival lesion in the maxillary left first premolar region was surgically excised, along with 1 mm of healthy surrounding gingiva. This resulted in complete healing, and no recurrence was observed during the 12-month follow-up period.
Photobleaching of pink photoluminescence in bandicoot fur
Authors: Reinhold Linda M.
Published: September 2023

Bright pink-orange-red photoluminescent (fluorescent and/or phosphorescent) fur is being found in an increasing number and diversity of mammal species. With the molecules causing these colours of photoluminescent emission suspected to be mostly photosensitive porphyrins, degradation from light exposure is an unquantified contributor to false negatives in museum-based surveys. I tested the resistance of pink photoluminescent bandicoot, Peramelidae, fur to exposure to natural sunlight and artificial laboratory lighting. Photoluminescence underwent visibly noticeable photobleaching in two minutes of direct sun exposure, or a few hours when exposed to indoor lighting. The fleeting nature of porphyrins means that an accurate representation of pink-orange-red photoluminescence should not be expected in specimens that have been exposed to light, whether in life, post-mortem, during taxidermy or on display.
PENGARUH ONLINE REVIEW DAN HARGA TERHADAP KEPUTUSAN PEMESANAN KAMAR HOTEL DI ONLINE TRAVEL AGENT (STUDI KASUS KOTA BATAM)
Authors: Alhamdi Rezki
Published: September 2023

Kota Batam merupakan salah satu kota besar yang ada di Indonesia. Batam merupakan kota yang dapat diakses melalui pelabuhan Malaysia dan Singapura. Adapun tujuan penelitian ini untuk mengetahui ada pengaruh Online Review dan Harga terhadap keputusan pemesanan kamar hotel pada online travel agent. Adapun cara pengumpulan data menggunakan kuesioner dan studi pustaka. Jumlah responden dalam penelitian ini sebanyak 100 orang dengan metode sampling yaitu purpose sampling. Analisis yang digunakan adalah analisis regresi linier berganda. Sebelumnya data dilakukan uji hipotesis, data dilakukan uji validitas, uji reliabilitas, uji asumsi klasik dengan uji normalitas, uji heteroskedasitas, uji multikolinearitas. Untuk menjawab hipotesis menggunakan Uji T dan Uji F. hasil uji t ditemukan bahwa pada penelitian ini maka dapat dijelaskan bahwa variabel online review dengan nilai sig 0.03 < dari 0.05 yang artinya ada pengaruh signifikasi online review terhadap keputusan pemesanan kamar hotel di Kota Batam. Pada variabel Harga mempunyai nilai sig 0.00 < dari 0.05 yang artinya ada pengaruh positif dan signifikasi antara harga dengan keputusan pemesanan kamar hotel. Berdasarkan hasil uji F dilakukan nilai sig 0.00 < dari 0.05 maka dapat dijelaskan bahwa ada pengaruh online review dan harga terhadap keputusan pemesanan kamar hotel di online travel agent.
Health Information in 2023 (and Beyond)
Authors: Klein William M. P. , Chou Wen-Ying Sylvia , Vanderpool Robin C.
Published: September 2023

This Viewpoint describes how health communication science can be used to improve response to health challenges by providing credible health information to the public.
Exploring the Application and Prospects of Synthetic Biology in Engineered Living Materials
Authors: Wang Qiwen , Hu Zhehui , Li Zhixuan , Liu Tiangang , Bian Guangkai
Published: September 2023

At the intersection of synthetic biology and materials science, engineered living materials (ELMs) exhibit unprecedented potential. Possessing unique “living” attributes, ELMs represent a significant paradigm shift in material design, showcasing self‐organization, self‐repair, adaptability, and evolvability, surpassing conventional synthetic materials. This review focuses on reviewing the applications of ELMs derived from bacteria, fungi, and plants in environmental remediation, eco‐friendly architecture, and sustainable energy. The review provides a comprehensive overview of the latest research progress and emerging design strategies for ELMs in various application fields from the perspectives of synthetic biology and materials science. In addition, the review provides valuable references for the design of novel ELMs, extending the potential applications of future ELMs. The investigation into the synergistic application possibilities amongst different species of ELMs offers beneficial reference information for researchers and practitioners in this field. Finally, future trends and development challenges of synthetic biology for ELMs in the coming years are discussed in detail.
Segmentation of plant residues on soil X‐ray CT images using neural network
Authors: Valdes‐Korovkin Ilya , Fomin Dmitry , Yudina Anna
Published: September 2023

In soil, plant residues have low contrast making them difficult to detect using X‐ray computed tomography. In this work, we tested a convolutional neural network (U‐Net) for its ability to improve the identification of crop residues in soil samples assembled from aggregates of different size fractions (small, large, water‐stable aggregates, and average aggregate composition). Soil CT images were obtained using a 244 μm resolution. About 2500 soil images were annotated to train the neural network, of which only 631 images were selected for the training data set. Intersection over Union (IOU) was used as a measure of success of segmentation by neural network, which takes values from 0 to 1. In the validation data set, IOU of background was 0.93, IOU of solid phase was 0.95, IOU of pore space was 0.77, and IOU of plant residues was 0.40. However, IOU of plant residues in the total data set increased to 0.7. Soil structure influences the quality of multiphase segmentation of soil CT images. The poorest segmentation of plant residues was in the soil samples composed of average aggregate size composition. The quality of pore space segmentation increased with increasing porosity of the soil sample. The model tends to generalize the large areas occupied by plant residues and overlooks the smaller ones. The low values of the IOU metric for plant residues in the training data set can also be related to insufficient quality of annotation of the original images.
Synthesis towards Phainanoid F: Photo‐induced 6π‐Electrocyclization for Constructing Contiguous All‐Carbon Quaternary Centers
Authors: Liu Hao‐Yuan , Zhang Zhen‐Yu , Zhou Yi‐Ke , Chen Jia‐Hua , Yang Zhen , Li Yuan‐He
Published: September 2023

In this paper, we report an efficient strategy for synthesizing the DEFGH rings of phainanoid F. The key to the construction of the 13,30‐cyclodammarane skeleton of the molecule was a photo‐induced 6π‐electrocyclization and a homoallylic elimination. Notably, this is a rare example of using electrocyclization reaction to simultaneously construct two vicinal quaternary carbons in total synthesis. The strategy outlined here forms the basis of our total synthesis of Phainanoid F, and it could also serve as a generally applicable approach for synthesizing other natural products containing similar 13,30‐cyclodammarane skeletons.
High‐Rate Discharge Minimizes Volume Expansion of Lithium Metal Electrodes under Lean Electrolyte and High Areal Capacity Conditions
Authors: Dutta Arghya , Mizuki Emiko , Matsuda Shoichi
Published: September 2023

The demand for practical implementation of lithium metal batteries (LMBs) is increasing due to their superior energy density. However, poor cycle life and safety concerns regarding dendrite formation remain significant challenges. Recent studies have shown empirical improvements in cycle life through the use of high‐rate discharge protocols, but the precise mechanism behind this enhancement is still unclear due to difficulties in analyzing the lithium electrode, especially in LMB cells with high energy density designs. In this study, X‐ray computed tomography (XCT) analysis, a non‐destructive technique, was employed to investigate the lithium metal electrode in pouch‐type cells with a cell‐level energy density exceeding 350 Wh kg−1. XCT analysis revealed significant volume expansion of the lithium electrode during charge/discharge cycles, particularly under high‐rate charging conditions, which promoted dendritic growth due to inhomogeneous current distribution. However, such undesired volume expansion was largely suppressed during high‐rate discharge, leading to improved cycle life. This study underscores the importance of non‐destructive techniques in comprehending the degradation mechanisms of high‐energy‐density LMBs.
Unravelling the interplay of local structure and valence transitions in Ce‐doped CaYAlO4 luminescent materials
Authors: Sun Wenhao , Liu Zihui , Xu Zhipeng , Zhang Yang
Published: September 2023

Cerium has been widely used as a dopant in luminescent materials due to its unique electronic configurations. It is generally anticipated that the luminescence properties of rare‐earth‐doped materials are closely related to the local environment of activators, especially for Ce3+. In addition, it is convenient to modulate its emission wavelength by adjusting the composition and structure. In this study, we systematically analyzed the microstructure of the Ce‐doped CaYAlO4 system at atomic resolution. The quantitive results indicated that the structure distortion greatly influenced the valence state of the Ce dopant, which is critical to its luminescence efficiency. In addition, valence variations also exist from surface to inner structure due to the big distortion area around the surface. Our results unravel the interplay of local structure and valence transitions in Ce‐doped aluminate phosphors, which has the potential to be applied in other luminescent materials.
Efficacy and safety of reduced‐dose chemotherapy plus immunotherapy in patients with lung squamous cell carcinoma: A real‐world observational study
Authors: Ouyang Ganlu , Liu Yanyang , Liu Jiewei , Huang Lin , Luo Feng , Li Lu
Published: September 2023

Background

Recently, chemotherapy plus immunotherapy has achieved remarkable efficacy in lung squamous cell carcinoma (LUSC). However, some patients, especially frail people, cannot tolerate full‐dose chemotherapy in the real world. To reduce toxicity, appropriate dose reduction in chemotherapy is necessary. Therefore, this study aimed to demonstrate the efficacy and safety of reduced‐dose chemotherapy plus immunotherapy in LUSC patients in the real world.

Methods

A real‐world observational study was conducted concerning patients who received chemotherapy plus immunotherapy in our situation. The primary endpoints were objective response rate (ORR) and disease control rate (DCR), and the secondary endpoints were progression‐free survival (PFS), overall survival (OS), and toxicity.

Results

Between December 2018 and January 2022, 110 patients were enrolled, of whom 54 patients were chemotherapy reduced‐dose group and 56 patients were chemotherapy standard‐dose group. The ORR in the reduced‐dose group is similar to standard‐dose group (85.19% vs. 71.43%, p = 0.082). Similar DCR were observed (100% vs. 94.64%, p = 0.086). Median PFS was 12 months in the reduced‐dose group and standard‐dose group, respectively. Median OS was 15 months and 16 months in the reduced‐dose group and standard‐dose group, respectively. We reported a lower incidence of grade 3–4 toxicity in the reduced‐dose group compared with standard‐dose group (27.78% vs. 42.86%, p = 0.100). The major toxic reactions were better alleviated in the reduced‐dose group than in the standard‐dose group, especially in the thrombocytopenia (p = 0.044), peripheral nerve damage (p = 0.001), gastrointestinal reactions (p < 0.0001), and fatigue (p = 0.001).

Conclusions

The modified regimen with attenuated doses of chemotherapy in combination with immunotherapy was effective and well tolerated in patients with LUSC. The efficacy of this modified regimen is similar to that of the full‐dose regimen.
Macrocyclization of Dienes under Confinement with Cationic Tungsten Imido/Oxo Alkylidene N‐Heterocyclic Carbene Complexes
Authors: Ziegler Felix , Bruckner Johanna R. , Nowakowski Michal , Bauer Matthias , Probst Patrick , Atwi Boshra , Buchmeiser Michael R.
Published: September 2023

Macrocyclization reactions are still challenging due to competing oligomerization, which requires the use of small substrate concentrations. Here, the cationic tungsten imido and tungsten oxo alkylidene N‐heterocyclic carbene complexes [[W(N‐2,6‐Cl2‐C6H3)(CHCMe2Ph(OC6F5)(pivalonitrile)(IMes)+ B(ArF)4−] (W1) and [W(O)(CHCMe2Ph(OCMe(CF3)2)(IMes)(CH3CN)+ B(ArF)4−] (W2) (IMes=1,3‐dimesitylimidazol‐2‐ylidene; B(ArF)4−=tetrakis(3,5‐bis(trifluoromethyl)phenyl borate) have been immobilized inside the pores of ordered mesoporous silica (OMS) with pore diameters of 3.3 and 6.8 nm, respectively, using a pore‐selective immobilization protocol. X‐ray absorption spectroscopy of W1@OMS showed that even though the catalyst structure is contracted due to confinement by the mesopores, both the oxidation state and structure of the catalyst stayed intact upon immobilization. Catalytic testing with four differently sized α,ω‐dienes revealed a dramatically increased macrocyclization (MC) and Z‐selectivity of the supported catalysts compared to the homogenous progenitors, allowing high substrate concentrations of 25 mM. With the supported complexes, a maximum increase in MC‐selectivity from 27 to 81 % and in Z‐selectivity from 17 to 34 % was achieved. In general, smaller mesopores exhibited a stronger confinement effect. A comparison of the two supported tungsten‐based catalysts showed that W1@OMS possesses a higher MC‐selectivity, while W2@OMS exhibits a higher Z‐selectivity which can be rationalized by the structures of the catalysts.
Lithium‐Ionen‐Batterie‐Elektroden neu denken
Authors: Gerl Stefan
Published: September 2023

Den CO2 Ausstoß minimieren und die Kosten senken. Das sind wesentliche Ziele, die Hersteller von Energiespeichern aktuell verfolgen. Die wichtigsten Stellhebel liegen in der Elektrodenfertigung. Sie unterliegt daher starken technologischen Veränderungen. Im Vormarsch sind Trockenelektroden, die maximale Wirtschaftlichkeit versprechen.
Anlagensicherheit aus Betreibersicht
Authors: Ohlendorf Frank , Beck Gerald , Albers Sören
Published: September 2023

Anlagenbetreiber in Schüttgut verarbeitenden Industrien profitieren, wenn Anlagenbauer die Anlagen nicht nur entwickeln und bauen, sondern auch selbst betreiben. Die Lohnherstellung schult den Blick für die Anforderungen, Pflichten und Herausforderungen der Betreiberseite. Produktsicherheit, Brand‐ und Explosionsschutz, Anlagen‐ und Bedienersicherheit sowie Umweltaspekte stehen automatisch deutlicher im Fokus.
Containment‐gerechtes Pulverhandling
Authors: Naudin Eric , Haverbeck Jens
Published: September 2023

Die Herstellung von APIs (Active Pharmaceutical Ingredient) in einem chemischen Prozess besteht in der Synthese organischer Verbindungen durch die Reaktion von Rohstoffen in einem Batch‐ oder kontinuierlichen Reaktorsystem. In diesem Artikel werden verschiedenen Anlagen zur Containment‐gerechten und arbeitssicheren Handhabung von Pulvern bei der Herstellung von API vorgestellt.
Vernetzte Dosier‐ und Abfüllanlagen steigern Effizienz und Qualität
Authors: Richter Achim
Published: September 2023

Mit vernetzten Produktionsprozessen und dem Einsatz automatisierter Fertigungssysteme können Unternehmen jeglicher Größe – sei es klein, mittelständisch oder konzernweit – ihre Flexibilität steigern, Kosten minimieren und Erträge erhöhen. Die Fricke‐Multiplex für die Parfüm‐ und Aromenindustrie gewährleistet präzise Dosierungen, kontrollierte Abfüllprozesse und Chargen‐Rückverfolgbarkeit, um eine gleichbleibende Produktqualität, Rezepturgenauigkeit, Einhaltung von Qualitätsstandards und Sicherheit für den Endverbraucher zu gewährleisten.
Face Name Associative Memory Exam and biomarker status in the ARMADA study: Advancing reliable measurement in Alzheimer's disease and cognitive aging
Authors: Rentz Dorene M. , Klinger Hannah M. , Samaroo Aubryn , Fitzpatrick Colleen , Schneider Olivia R. , Amagai Saki , Peipert John Devin
Published: September 2023

The Face Name Associative Memory Exam (FNAME) was introduced into the NIH Toolbox as part of the ARMADA study and establishes normative data for diverse participants, ages 64 to 85+, and proposes cutoff scores between biomarker positive versus negative (+/−) groups. The FNAME was administered to 257 participants across the clinical spectrum with 122 having amyloid biomarkers. Linear regression explored the association between demographics and FNAME and between amyloid (+/−) groups. Receiver operating characteristic curves (ROC) identified performance thresholds that best discriminated between biomarker (+/−) individuals. Lower FNAME scores occurred in males, older ages, Black/African Americans, Hispanics, and biomarker‐positive participants. ROC analyses demonstrated acceptable accuracy (0.73 to 0.77) but only when combined with clinical status. The diagnostic discrimination of amyloid positivity was acceptable but not excellent, suggesting the FNAME may be a better screening indicator of clinical status rather than amyloid deposition in cognitively normal individuals. Normative data are provided.
Building block copolymer particles via self‐assembly within a droplet
Authors: Zhang Sen , Bao Han , Shen Xinyi , Song Yongyang , Wang Shutao
Published: September 2023

The self‐assembly of block copolymers (BCPs) within emulsion droplets is a flexible strategy for the preparation of polymer particles. This strategy permits the fine‐tuning of shapes, internal structures, and surface nanostructures of the polymer particles, thus allowing many applications. Although some literature has reviewed the BCP preparation via self‐assembly within a droplet, a comprehensive summary including in‐depth understanding, controllable preparation, and application is lacked. In this review, we systematically delve into the multiple mechanisms that drive BCP self‐assembly within emulsion droplets, such as commensurability effects for minimizing total free energy, interfacial instability, organized spontaneous emulsification, phase separation of multiple components, and entropy effects between BCPs and nanoparticles. Additionally, a strategy combining selective cross‐linking and disassembly can further generate Janus particles featuring unique structures. Next, various applications across multiple disciplines are discussed, including drug delivery, display, biomedical imaging, macromolecular separation, and fuel cells. Finally, we present an overview of the current challenges and future directions for BCP emulsion self‐assembly, covering mechanism investigation, molecular design, stability control, and application exploration. We anticipate deeper understanding, more varieties, enhanced performance, and broader applications can be achieved with BCP emulsion self‐assembly after addressing the challenge.
A review on flaxseeds: Nutritional profile, health benefits, value added products, and toxicity
Authors: Pramanik Jhilam , Kumar Akash , Prajapati Bhupendra
Published: September 2023

Flaxseed has been consumed by people for a very long time due to its nutritional value and medicinal applications. In India, flaxseed is used for both culinary and medicinal reasons. About 45% of alpha‐linolenic acid (ALA), 28%–30% protein, and 35% fiber are present in flaxseeds. The finest source of omega‐3 fatty acids for those who do not consume seafood is flaxseed. Flaxseeds have lignin, of which primary lignan is secoisolariciresinol diglycoside, with low amounts of isolariciresinol, lariciresinol, pinoresinol, and matairesinol. Flaxseed is probably safe for most grown‐ups. The daily number of bowel movements may increase if flaxseed is included in the diet. Additionally, it may result in side effects such as gas, bloating, stomach pain, and nausea. Higher dosages are probably going to cause more secondary effects. Due to the nutritional profile of flaxseeds, they exhibit various health benefits which include; improving cardiac health, improving brain development, improving skin health, improving gut health, maintaining blood sugar level, reducing the risk of renal diseases, and several types of cancers. The purpose of this study is to provide a general overview of the nutritional profile, health benefits, value‐added products, and toxicity of flaxseeds.