bluuebunny/crossref_metadata_2025 huggingface dataset:
Por una semiótica del selfie en la cultura visual digital
Authors: Broullón-Lozano Manuel A.
Published: May 2019

En primer lugar, el fenómeno selfie consiste simplemente en volver del revés la sintaxis fotográfica con el fin de hacer coincidir en la misma instancia al fotógrafo y al objeto fotografiado. No obstante, más allá de esta operación, el selfie tiene que ver con el régimen escópico de la sociedad de comienzos del siglo XXI. El presente ensayo analiza un archivo de fotografías digitales tomadas y publicadas en Internet durante el año 2014, todas ellas compuestas de acuerdo con esta estructura enunciativa auto-consciente. En último término, se tratará de establecer una tipología cultural semiótica en torno a la estructura del ver y del ser visto a través de la web 2.0. Abstract:First of all, the selfie phenomena consists on turning inside the photoghraphic syntax, in order to concentrate into the same instance the photographer and the object of the photography. In addition to this, it has to deal with the visual structure of the society at the begining of the XXIst century. On that way, this essay may analyze some digital pictures which has been taken and published on the Internet during the year 2014 which have been composed according to this self conscient enunciation. At least we may be able to build a semiotic cultural typology about the structure of watching and being watched through the web 2.0.Palabras clave:selfie; sí mismo; cultura visual digital; fotografía digital; panopticon; semiótica.Keywords:Selfie; Self; Visual Digital Culture; Digital Photography; Panopticon; Semiotics.
¿Qué es la crítica de cine?
Authors: Reseña de Carmen Rodríguez Fuentes Luis Navarrete Cardero.
Published: May 2019

Reseña del libro ¿Qué es la crítica de cine?
Contemporary differences between men and women with acute coronary syndromes: CIAM multicenter registry
Authors: Plaza-Martín María , Sanmartin-Fernandez Marcelo , Álvarez-Álvarez Belén , Andrea Ruth , Seoane-García Tania , González-D’Gregorio Jessika , Hernández-Betancor Iván , Rozado José , Carrasco-Ávalos Francisco , del Mar Alameda-Ortiz María , Gómez-Talavera Sandra , Sanchís Juan , Anguita Sánchez Manuel , Peral-Disdier Vicente , Ibáñez Borja , del Prado Díaz Susana , Zamorano Gómez José L.
Published: May 2019

Aim

Differences exist in the diagnosis and treatment of acute coronary syndrome (ACS) between men and women. However, recent advancements in the management of ACSs might have attenuated this sex gap. We evaluated the status of ACS management in a multicenter registry in 10 tertiary Spanish hospitals.

Methods

We enrolled 1056 patients in our study, including only those with type 1 myocardial infarctions or unstable angina presumably not related to a secondary cause in an ‘all-comers’ design.

Results

The women enrolled (29%) were older than men (71.0 ± 12.8 vs. 64.0 ± 12.3, P = 0.001), with a higher prevalence of hypertension (71.0 vs. 56.5%, P < 0.001), insulin-treated diabetes (13.7 vs. 7.9%, P = 0.003), dyslipidemia (62.2 vs. 55.3%, P = 0.038), and chronic kidney disease (16.9 vs. 9.1%, P = 0.001). Women presented more frequently with back or arm pain radiation (57.3 vs. 49.7%, P = 0.025), palpitations (5.9 vs. 2.0%, P = 0.001), or dyspnea (33.0 vs. 19.4%, P = 0.001). ACS without significant coronary stenosis was more prevalent in women (16.8 vs. 8.1%, P = 0.001). There were no differences in percutaneous revascularization rates, but drug-eluting stents were less frequently employed in women (75.4 vs. 67.8%, P = 0.024); women were less often referred to a cardiac rehabilitation program (19.9 vs. 33.9%, P = 0.001). There were no significant differences in in-hospital complications such as thrombosis or bleeding.

Conclusion

ACS presenting with atypical symptoms and without significant coronary artery stenosis is more frequent in women. Selection of either an invasive procedure or conservative management is not influenced by sex. Cardiac rehabilitation referral on discharge is underused, especially in women.
Type 2 myocardial infarction: a grim diagnosis with different shades of gray
Authors: Dahhan Ali
Published: May 2019

Type 2 myocardial infarction (MI) is commonly encountered in daily practice. Its incidence can range between 5 and 35% among all cases of MI. It is caused by disorders that result in supply–demand mismatch, which leads to myocardial ischemia and necrosis. Therefore, unsurprisingly, it is frequently diagnosed in critically ill patients and those with severe coronary artery disease (CAD) and multiple comorbidities. Though it can occur in the absence of CAD, the presence of coronary blood flow-limiting stenoses can allow even minor insults to disturb the already fine supply–demand balance. Generally, type 2 MI may be associated with higher mortality; however, some data suggest it may have different severities, and outcome is better in patients with type 2 MI of milder severity. Nonetheless, regardless of the causes (ischemic or nonischemic), troponin elevation is associated with worse outcome. Differentiating type 2 MI from other causes of myocardial necrosis, mainly type 1 MI and myocardial injury, remains a clinical challenge. Different diagnostic tools can be utilized to aid in reaching an accurate diagnosis. These can include contrast echocardiography, computed tomography, MRI, radionuclide imaging, coronary angiography, and intracoronary imaging. However, each comes with its own limitations and results should be interpreted with caution and in clinical context. Management of type 2 MI is uncertain because of paucity of data. Evidence-based therapies of type 1 MI are frequently used, though this may be harmful sometimes. Therefore, clinical judgment should be used, and management and therapies should be tailored to each individual case.
Optimal number of plants and planting methods of best bean varieties in Korça Region
Authors: Maho Adrian , Skënderasi Besnik
Published: May 2019

White bean is one of the mayor legumes, which covers a wide surface in planting structure. High yields are closely related to the right regionalization of this crop and the implementation of agrotechnical provisions.

One of the most important agrotechnical issue is: to determine the optimal number of plants in regard to the distance between rows and the distance of plants in a row.

Depending on the morphological differences of beans, the number of plants per unit of surface should change. In order to determine this optimal number, it is necessary to experiment different plant varieties with an average number of 250-400 thousand plants / ha.

The study was carried out by experimenting two autochthonous varieties Eҫmeniku and Trenare (they were evaluated as the best varieties in Korça District among 5 experimented varieties.)

The study aims to identify the influence of the plant number and planting method on the production results.

For this purpose, we studied the varieties with a distance of 5-12 cm between plants in a row (distance between rows 60 cm), with a number of about 50,000 plants per hectare.

We used two planting methods, that of individual planting of beans and the bouquet planting where the beans are placed 2 by 2.

We draw respective conclusions based on experimental results calculated according to the three-factorial statistical analysis.
Study on Thinking Paradigms Changes in Environmental Educational Systems
Authors: Stan Simona Nicoleta , Amalia-Gianina Străteanu
Published: May 2019

The current major concerns of mankind with regard to biodiversity, food safety and security, demographic growth, pollution, the energy crisis, ecosystem productivity, environmental protection and environment are only a part of the contemporary concerns that environmental education must say the word.

An analysis of the situations that generates global environmental problems highlights the need for an extensive environmental curriculum with studies on human behavior, crisis and disaster management, bioeconomics, psychology of thinking styles, neuroscience, etc. The design of new programs should be directed to proactive behaviors and leadership, to entrepreneurship and innovation, with a direct impact on the ability to find solutions to solve environmental problems.
Crisis and Opportunities at the Intersection Between Food, Agri-Bussiness and Health
Authors: Stan Simona Nicoleta , Amalia-Gianina Străteanu
Published: May 2019

In the current context, food safety crises often have a direct impact on the health of the European population. Such moments bring chaos and confusion among the population, about food consumption, food systems, the ethics of businesses involved in the agri-food chain, or about guaranteeing their consumers’ rights.

Although the level of consumer information has increased in recent years, there is a need for a uniform approach to all topics of interest to them, from quality, cost, authenticity, maintenance of food safety, to contaminants and fraud.

Choosing a diet generates multiple effects on the quality of human life. Europeans are concerned about how food products are produced and consumed and which are the short and long-term effects, with attention being shifted from providing sufficient food. However, food consumption patterns of European citizens often have negative health consequences, endangering the future and making it necessary to change the way we feed and consume them. From farms to restaurants, we need to redefine the assumed concept of adequate nutrition in the 21st century: sustainable diets from sustainable food systems.
The Role and Importance of Book Culture in the Activities of the Czech Slovakophile Movement in the 19th Century
Authors: Jurčišinová Nadežda
Published: May 2019

An important role in the activities of the Slovakophile movement, which was born in Bohemia and Moravia at the end of the 1870s, was played by book culture. Especially by means of books and articles in magazines, Czech Slovakophiles acquainted the wider Czech public with the position of Slovaks in Hungary and aroused interest in the development of Czech-Slovak solidarity. A significant role in this activity was played by the national-defence and Slovakophile association Czechoslovak Unity in Prague (1896–1914), which would send the Slovaks books and magazines, and even the entire libraries. Cooperation in this area was supported even by T. G. Masaryk, but especially by such Slovakophiles as Rudolf Pokorný, Josef Holeček, Adolf Heyduk, Karel Kálal, Jaroslav Vlček, František Pastrnek and František Bílý.
The Illustrations of the Balzer and Rybička Families in Books Published Outside of Prague
Authors: Štefan Jan T.
Published: May 2019

The article provides information on two families of engravers that were involved in book illustrations in Bohemia over a hundred years beginning in the 1760s. Jan Jiří Balzer and his brothers (František, Matyáš and Řehoř) and sons (Jan Karel and Antonín Karel) significantly contributed to the development of engraving craft and graphic art in Bohemia. His international business activities in the area of graphic arts are known. After the death of Jan Balzer, the engraving and printing workshop was managed by his wife Kateřina and the mentioned brother Řehoř. At the beginning of the 19th century, Balzer’s daughter married an engraver in Balzer’s workshop, Karel Rybička. Their son Josef, thus a grandson of Jan Balzer, subsequently became a significant steel engraver. Both families, of Balzer and Rybička, were engaged in book illustration. This work discusses their illustrations, realised fully by or in cooperation with publishing houses in various towns of the Austrian monarchy other than Prague as well as outside the monarchy. The graphs in the article show the frequency of these illustration activities in dependence on time for the families of both Balzer and Rybička (whose father could have been involved in the steel-engraving illustrations as well).
All-Metal Book Bindings in the 19th Century
Authors: Slovik-Vávrová Hana , Slovik Radomír
Published: May 2019

The article presents the results of the research activities of Hana Slovik-Vávrová concerning the mapping of preserved all-metal brass book bindings in the collections of institutions in the Czech Republic. She has recorded a total of 145 of these exceptional book bindings from between the end of the 18th century and the 1920s, coming from 18 organisations. All-metal book bindings have not been devoted enough attention although they represent a very interesting chapter in the history of book binding. An outcome of this work is a comprehensive description and detailed documentation of all researched all-metal book bindings. A valuable part is a catalogue of book bindings and of ornaments used in the decoration of all-metal book bindings.
Personal Libraries in the National Museum – a Valuable Source of Information on the History of Book Culture in the 19th Century and the Early 20th Century
Authors: Kašparová Jaroslava
Published: May 2019

Book collections from the 19th century and the first half of the 20th century preserved in the NM are among the richest and most interesting book collections of the Czech Republic. Research into personal book collections of the NM within the NAKI project (2012–2015), including besides the historical book collection also books from the 19th and 20th centuries, has provided valuable information on the history of the entire book culture. The PROVENIO database is an important source of information and knowledge in terms of book owners and ownership provenance, library history, bibliophilia and the reception by readers, as well as the history of book binding, book publishing houses and book trade of the given period.
Books in Burgher Households on the Moravian-Silesian Border at the Beginning of the 19th Century
Authors: Nováková Lenka
Published: May 2019

The relation of subjected municipalities of urban type on the Moravian-Silesian border to books and to education in general can be demonstrated on the example of Místek, situated in the Hukvaldy demesne. The craftsmanship–agricultural character of the town along with its position on a trade route near the Moravian-Silesian border was involved in the shaping of the social environment. Valuable sources of information on burgher households are probate inventories. It is possible to determine from them not only whether burghers owned any books at all and how many, but sometimes even what types of books they were. Among others, likewise the information on book owners, their profession and financial situation is undoubtedly interesting. Although personal motives and the attitudes of Místek burghers towards books usually remain hidden from us, it is still possible to reveal a part of everyday life.
The Development of the Book Collection of the Detvan Association in Prague until the End of the 19th Century
Authors: Hedmeg Lukáš
Published: May 2019

At the turn of the 20th century, Slovaks faced new national challenges in the political and social conditions of Austria-Hungary. The Hungarisation efforts of the Hungarian government along with frequent accusations of pan-Slavism motivated a part of Slovak students coming from a nationally conscious environment to leave for studies in the Czech part of the monarchy. From its foundation in 1882, the Detvan association in Prague planned to develop educational and literary activities with an emphasis on the Slovak language and culture. This led to an urgent need for the establishment of the association’s own library, which could be used by its members. The article focuses its attention on the creation and systematic expansion and improvement of the book collection of the Detvan association between 1882 and the end of the 19th century. It primarily deals with the growth, subdivision and genre profiling of the library and, last but not least, also with lending activities, closely associated with that.
Jindřichův Hradec and the Landfras Family of Printers
Authors: Fürbach František
Published: May 2019

The beginning of the article briefly outlines the history of Jindřichův Hradec from its foundation through its development in the 15th century and especially in the 16th century, until the 19th century, when the Landfras printing works functioned in the town. Afterwards, the article focuses on the Landfras family of printers and its work in Jindřichův Hradec. It deals with the founder of the printing works, Josef Jan Landfras (1869–1840), as well as with his family background and his public activities. Most attention is devoted to his successor, Alois Landfras (1797–1875), who became one of the most remarkable figures in the history of Jindřichův Hradec, because he was very actively involved in social events in the town. From 1841, he was a member of the town council; ten years later, he was elected mayor and remained in the position for ten years. His private and family life is marginally mentioned as well. The last member of the family active in the 19th century was Vilém Antonín Landfras (1830–1902), who was also a member of the town council. Thanks to him, the weekly Ohlas od Nežárky [Echoes from the River Nežárka] began to be published in the town in 1871. The article further mentions his important role in the organisation of the social entertainment of burghers and his family life. The end of the paper is devoted to his son, Vilém Bohumil Landfras (1865–1931), whose work falls into the first third of the 20th century.
From the Legacy of the Landfras Printing Works in the Jindřichův Hradec Archives – a Mirror of Time in Family Correspondence
Authors: Hálová Helena
Published: May 2019

The article studies the set of 27 original letters deposited in the Documentation Collection – Cultural-Historical Archives of the State District Archives of Jindřichův Hradec. This collection contains documents of non-official provenance concerning, among other topics, also remarkable figures of the town. A leading position among them is assumed by the Landfras family, whose members were not only owners of a prosperous printing works, but also patriots, leaders of the town, and supporters of education, societies and culture. The letters provide an insight into the private lives of the members of the Landfras family, in particular its most significant member, Alois Landfras, and people connected with the family. The article deals with an overall comparison of the letters. It studies references to them and to events in their family, and connections with their life in Jindřichův Hradec. It adds some less known information on the studies of Alois Landfras at the university in Prague, providing an insight into his inner world. The article is complemented by a synoptic table of all letters, including the quoted persons and places.
The Promotion of Pilgrimage Sites in Moravia through Broadside Ballads in the First Half of the 19th century
Authors: Ivánek Jakub , Szturcová Monika
Published: May 2019

The article deals with broadside ballads with themes related to pilgrimage, which were used by Moravian pilgrims from the 1790s, but mainly in the first half of the 19th century. The period under study thus begins after the death of the Enlightenment ruler Joseph II, who introduced a number of restrictive measures into the pilgrimage system, which altered the pilgrimage practice. The quantity of pilgrimage songs then published as broadside ballads proves the unceasing interest of especially commoners in pilgrimages and the culture associated with them. The songs themselves, however, occasionally mirror the new situation. The first case is represented by songs about the pilgrimage sites abolished by the reforms of Joseph II and later (mostly from the second quarter of the 19th century) renewed (an analysis on the examples of Bludov and Hostýn). The second case includes newly established pilgrimage sites, which sometimes claim allegedly ancient history but are often only local replacements for more remote pilgrimage sites (an analysis on the examples of Jalubí and Lutršték near Němčany). The main role in the restoration and establishment of pilgrimage sites at that time was played by commoners, often peasants, who, after the Enlightenment reforms, assumed the role previously reserved for higher-ranking people (the nobility, clergy and burghers). Likewise the literature promoting the new or restored sites comes from these circles, which is reflected in a certain primitiveness of expression, yet interspersed with remnants of Baroque stereotypes.
Mariazell in Printed Media of the 18th and 19th Centuries
Authors: Holubová Markéta
Published: May 2019

In the wide range of printed books on religious topics, a specific role was played by printed pilgrimage items, whose main aim was to increase the prestige and fame of pilgrimage sites and to strengthen the promotion of worshipped cults among believers. This was also the case of the pilgrimage site of Mariazell in Styria, Austria, where believers from virtually all parts of the Habsburg Monarchy, thus also pilgrims from the Czech lands, travelled in the 18th and 19th centuries. Especially broadside-ballad production and pilgrimage books significantly developed the tradition of religious pilgrimages. Pilgrimage songs, which were published in pilgrimage books intended for pilgrims heading to Mariazell, found a response in broadside-ballad production and in many cases also became part of the song repertoire of pilgrim cults in the Czech lands.
The Trnkas of Křovice: The Short Rise of a Forgotten Family
Authors: Županič Jan
Published: May 2019

Changes in the social status of the elites have been relatively well-mapped in the case of the families of the higher nobility, more rarely also for some better-off knightly families. Nevertheless, research has ignored the fates of the noble families that did not settle in the country but were tied to (mainly royal) towns and that completely blended in the 18th and 19th centuries with the local dignitaries and ceased to use their aristocratic attributes, especially nobiliary particles.
Duplex Quantitative Polymerase Chain Reaction of ISG15 and RSAD2 Increases Accuracy of Early Pregnancy Diagnosis in Dairy Cows
Authors: Cheng Lei , Xiang Min , Hu Xiuzhong , Yu Jie , Xia Yu , Tao Bifei , Zhao Shuhong
Published: May 2019

Early diagnosis of pregnancy is important in livestock production, but there is no reliable technology used for pregnancy diagnosis within the first three weeks after insemination. During early pregnancy, the expression of interferon-stimulating genes (ISGs) in peripheral blood leukocytes (PBL) is significantly increased. However, due to different strains, detection sample types, detection methods, threshold value, etc. the specific effectiveness of early pregnancy diagnosis using ISGs is worth further study. The purpose of this study was to test interferon-stimulated protein 15 (ISG15), 2'–5'-oligoadenylate synthetase 1 (OAS1) and radical S-adenosyl methionine domain containing 2 (RSAD2) for early pregnancy diagnosis in dairy cows. The expression of ISG15, OAS1, and RSAD2 in PBL of pregnant and non-pregnant heifers on days 0, 14, 18, 21 and 28 after artificial insemination (AI) was detected by fluorescence quantitative polymerase chain reaction (PCR). The sensitivity and specificity of the pregnancy diagnosis was analyzed using expression of these three genes separately or in combination by receiver operating characteristic curve. The combination with the highest accuracy used probe primers and duplex fluorescence quantitative PCR. The single quantitative PCR results showed that expression of ISG15, OAS1 and RSAD2 on day 18 after AI was significantly higher in pregnant than in non-pregnant cows. When these three genes were used separately, or in combination, for early pregnancy diagnosis, the sensitivity for the RSAD2 gene was 100%, and the combination of ISG15 with RSAD2 was 94.7%. The duplex quantitative PCR showed that, although the sensitivity of ISG15 alone was 100%, its specificity was only 88.2% (cut-off value 1.402). The sensitivity of RSAD2 alone was 89.5%, and the specificity was 88.2%; however, when the two genes were used in combination, the sensitivity, specificity and diagnostic cut-off value were consistent with the results of single quantitative PCR. These results indicated that a duplex quantitative PCR assay system for early pregnancy diagnosis in cows using ISG15 and RSAD2 was established. Simultaneous detection of expression of ISG15 and RSAD2 by duplex quantitative PCR can effectively improve the diagnostic accuracy for dairy cows.
The Effect of Slaughter Age and the Diet in the Final Growth Phase of Poulards on Productivity and Meat Quality
Authors: Krawczyk Józefa , Obrzut Joanna , Świątkiewicz Sylwester , Calik Jolanta
Published: May 2019

The aim of the studies was to evaluate the effect of the diet in the final growth phase and slaughter age of poulards on productivity, dressing percentage, carcass colour and physicochemical properties of meat. The studies were conducted on 78 hybrids obtained by crossing Ross 308 broiler roosters with Rhode Island Red (R-11) dual-purpose laying hens (♂Ross 308 × ♀R-11). Birds were assigned to 3 groups: control group (K) fed starter, grower and finisher diets without addition of dairy products, experimental group S offered a finisher diet supplemented with 4% whey, and experimental group M receiving 4% milk powder supplement in the final growth phase. Spaying procedure was carried out at 8 weeks of age. Poulards were slaughtered at 18 and 20 weeks of age. The studies showed that by using hybrids of dual-purpose hens with broiler roosters for production of poulards, rearing period could be shortened to 18 weeks, and the obtained meat had comparable or even better quality traits compared with poulards slaughtered at 20 weeks of age. Supplementation of poulard diet with 4% whey or milk powder in the final growth phase had a beneficial effect mostly on improvement of sensory properties of meat. There were not many significant differences in meat quality between poulards fed the diet supplemented with milk and whey but instead there were differences between these groups and the control group fed the diet without these additives.
Cystic fibrosis related diabetes
Authors: Pop Liviu-Laurențiu , Dediu Mihaela , Velea Iulian , Mogoi Mirela , Ciuca Ioana M.
Published: May 2019

Cystic fibrosis related diabetes (CFRD) is a redoubtable complication associated to cystic fibrosis, with an increasing frequency, directly proportional to children life expectancy. Although this complication has similar features with DM type 1 and some with type 2, the evolution and even the response to insulin therapy is different. It is also possible that other factors to influence the CFRD clinical expression and subsequently the disease evolution. Since its 1t diagnosis was associated with more frequent pulmonary exacerbations and with the deterioration of the respiratory status, therefore CFRD must be early and correctly diagnosed and managed. The aim of this paper is to present an overview of the recent updates and recommendations regarding this important CF complication.
Evolution of Acinetobacter baumannii infections and antimicrobial resistance. A review
Authors: Popovici Sonia Elena , Bedreag Ovidiu Horea , Sandesc Dorel
Published: May 2019

The emergence of multi-drug resistant Acinetobacter spp involved in hospital-acquired infections, once considered an easily treatable pathogen, is troublesome and an immense burden for the modern medical systems worldwide. In the last 20 years the medical community recorded an increase in the incidence and severity of these infections as therapeutic means tend to be less and less effective on these strains. The ability of these bacteria to rapidly develop resistance to antimicrobial agents by continuously changing and adapting their mechanisms, their ability to survive for long periods of time in the hospital environment and the multitude of transmission possibilities raises serious issues regarding the management of these complex infections. The future lies in developing new and targeted methods for the early diagnosis of A. baumannii, as well as in the judicious use of antimicrobial drugs. This review details the evolution of the pathogenicity of this microorganism, together with the changes that appeared in resistance mechanisms and the advancements in molecular testing for the early detection of infection.
Pharmacological therapies for acute respiratory distress syndrome
Authors: Ivaşcu Robert , Torsin Ligia , Morlova Darius , Stanca Alina , Neguţu Mihai , Negoiţă Silvius , Duţu Mădălina
Published: May 2019

Acute respiratory distress syndrome (ARDS) has no specific treatment, the only effective therapy currently being limited to minimizing potentially harmful ventilation and avoiding a positive fluid balance. These treatments could not be completely effective in severe disease and several measures must be undertaken simultaneously, including pharmacological therapies aimed at correcting the etiology or targeting the pathogenesis. In this review article we provide update on pharmacological therapies in ARDS, showing their effect on outcome in recent trials.
Molecular characterization and Immunodiagnostic potential of various antigenic proteins of Fasciola gigantica species isolated from sheep of North West Himalayan Region
Authors: Dar J. S. , Ganai B. A. , Shahardar R. A. , Zargar U. R.
Published: May 2019

The control of the digenetic trematode Fasciola gigantica has been the major challenge in both cattle and small ruminants as there is a paucity of an effective and commercial vaccine. Thus, the accurate identification and prepatent diagnosis of F. gigantica is an essential prerequisite for its successful prevention and control. In the present study, the morphologically identified specimens isolated from the liver and bile ducts of sheep (Ovis aries) were validated through molecular data. The sequence analysis of ITS-2 of our isolates showed high degree of similarity with F. gigantica and F. hepatica using BLAST function of NCBI. The phylogenetic analysis of our isolates showed a close relationship with previously described F. gigantica and F. hepatica isolates from different countries. The antigenic profile of somatic and E/S antigens of F. gigantica were revealed by SDS–PAGE and immunoblotting using sera from sheep naturally infected with F. gigantica. By SDS-PAGE, 20 distinct bands were revealed from crude somatic fraction. Immunoblotting analysis of these proteins with positive sera exhibited 8 sero-reactive bands ranging from 14 to 97 kDa. Among these 38 and 44 kDa bands were quite specific with high diagnostic specificity and sensitivity. The E/S fraction comprised 7 distinct bands, as revealed by SDS-PAGE analysis. Immunoblotting analysis of these proteins with positive sera exhibited 6 antigenic bands ranging from 23 – 54 kDa. Among these 27 and 33 kDa were found to be quite specific with high diagnostic specificity and sensitivity. The present study concludes that the protein bands of 38 and 44 kDa in somatic fraction and 27 and 33 kDa in E/S fraction can be used for the immunodiagnostic purpose for this economically important parasite, which may also entice further studies regarding their vaccine potential.
Preliminary evidence for the occurrence of β-tubulin isotype 3 polymorphisms in Fasciola hepatica isolates in cattle and sheep in Turkey
Authors: Canakoglu S. Sadet , Simsek S. , Balkaya I. , Kilinc S. Gunyakti
Published: May 2019

Fasciolosis caused by Fasciola hepatica is a common parasitic disease of livestock especially sheep and cattle. In this study molecular characterization of β-tubulin isotype 3 gene in Fasciola hepatica isolates from cattle and sheep in Turkey was carried out. For this purpose a total of 80 adult Fasciola hepatica isolates were collected from 20 sheep and 20 cattle in Kayseri and Erzurum provinces. PCR-RFLP was performed on β-tubulin isotype 3 gene and MboII revealed two fragments of approximately 350 bp and 390 bp, whereas HphI enzyme yielded 210, 340 and 540 bp bands, HindII yielded 380 and 450 bp bands in all samples. A total of 80 isolates were tested by SSCP and all of them presented the same band profiles. Six samples (4 sheep and 2 cattle) were randomly selected and DNA sequence of a 935 bp coding fragment of β-tubulin isotype 3 was performed. Sheep samples were more polymorphic than the cattle. This β-tubulin isotype 3 gene polymorphism of F.hepatica isolates from sheep and cattle of two distinct geographical areas of Turkey have been investigated for the first time.
Interventional Treatment of Cardiac Emergencies in Children with Congenital Heart Diseases
Authors: Cinteza Eliza Elena , Nicolescu Alin Marcel , Filip Cristina , Nicolae Georgiana , Duica Gabriela , Grigore Cosmin Alexandru , Mahmoud Hyam
Published: May 2019

Cardiac emergencies in children represent an extremely important issue in medical practice. In general, interventional treatment could be optional in many situations, however it can be indicated in emergency conditions. There are many diseases at pediatric age that can benefit from interventional treatment, thus reducing the surgical risks and subsequent complications. Balloon atrioseptostomy, patent ductus arteriosus (PDA) closure, percutaneous or hybrid closure of a ventricular septal defect, pulmonary or aortic valvuloplasty, balloon angioplasty for aortic coarctation, implantation of a stent for coarctation of the aorta, for severe stenosis of the infundibulum of the right ventricle, or for PDA correction are among the procedures that can be performed in emergency situations. This review aims to present the current state of the art in the field of pediatric interventional cardiology.
Classification of Water Quality of Banat Watercourses in Serbia for the Needs of Irrigation
Authors: Ilić Milica , Vranešević Milica , Bezdan Atila , Blagojević Boško
Published: May 2019

The composition of water used for irrigation has a significant impact on the production characteristics of the land, yield and irrigation equipment, and therefore its analysis, or assessment of the usability of irrigation water is very important. In this paper, the potential impact of the waters of the Banat watercourses of Moravica, Karaš and Nera is assessed on the basis of monthly water samples from the measuring stations of Vatin, Dobričevo and Kusić, for the period of April-September from the year 2007 to 2017. The assessment was carried out using the classification of irrigation water: FAO, USLL and water categorization according to Nejgebauer, and the Serbian Water Quality Index (SWQI). For the needs of these classifications, a total of 20 water parameters were analyzed: quality, physical, chemical and biological parameters. According to all the classifications, the analyzed watercourses can be a good source of water for irrigation in terms of its quality, but with control and appropriate measures, in particular, the presence of bicarbonate, but also the ratio of Na+ to Ca2+ and Mg2+.
Cardinality Estimators do not Preserve Privacy
Authors: Desfontaines Damien , Lochbihler Andreas , Basin David
Published: May 2019

Cardinality estimators like HyperLogLog are sketching algorithms that estimate the number of distinct elements in a large multiset. Their use in privacy-sensitive contexts raises the question of whether they leak private information. In particular, can they provide any privacy guarantees while preserving their strong aggregation properties?

We formulate an abstract notion of cardinality estimators, that captures this aggregation requirement: one can merge sketches without losing precision. We propose an attacker model and a corresponding privacy definition, strictly weaker than differential privacy: we assume that the attacker has no prior knowledge of the data. We then show that if a cardinality estimator satisfies this definition, then it cannot have a reasonable level of accuracy. We prove similar results for weaker versions of our definition, a nd a nalyze t he p rivacy o f existing algorithms, showing that their average privacy loss is significant, e ven f or m ultisets w ith l arge cardinalities. We conclude that strong aggregation requirements are incompatible with any reasonable definition o f privacy, and that cardinality estimators should be considered as sensitive as raw data. We also propose risk mitigation strategies for their real-world applications.
4 Years of EU Cookie Law: Results and Lessons Learned
Authors: Trevisan Martino , Traverso Stefano , Bassi Eleonora , Mellia Marco
Published: May 2019

Personalized advertisement has changed the web. It lets websites monetize the content they offer. The downside is the continuous collection of personal information with significant threats to personal privacy. In 2002, the European Union (EU) introduced a first set of regulations on the use of online tracking technologies. It aimed, among other things, to make online tracking mechanisms explicit to increase privacy awareness among users.

Amended in 2009, the EU Directive mandates websites to ask for informed consent before using any kind of profiling technology, e.g., cookies. Since 2013, the ePrivacy Directive became mandatory, and each EU Member State transposed it in national legislation. Since then, most of European websites embed a “Cookie Bar”, the most visible effect of the regulation.

In this paper, we run a large-scale measurement campaign to check the current implementation status of the EU cookie directive. For this, we use CookieCheck, a simple tool to automatically verify legislation violations. Results depict a shady picture: 49 % of websites do not respect the Directive and install profiling cookies before any user’s consent is given.

Beside presenting a detailed picture, this paper casts lights on the difficulty of legislator attempts to regulate the troubled marriage between ad-supported web services and their users. In this picture, online privacy seems to be continuously at stake, and it is hard to reach transparency.
Privacy Loss Classes: The Central Limit Theorem in Differential Privacy
Authors: Sommer David M. , Meiser Sebastian , Mohammadi Esfandiar
Published: May 2019

Quantifying the privacy loss of a privacy-preserving mechanism on potentially sensitive data is a complex and well-researched topic; the de-facto standard for privacy measures are ε-differential privacy (DP) and its versatile relaxation (ε, δ)-approximate differential privacy (ADP). Recently, novel variants of (A)DP focused on giving tighter privacy bounds under continual observation. In this paper we unify many previous works via the privacy loss distribution (PLD) of a mechanism. We show that for non-adaptive mechanisms, the privacy loss under sequential composition undergoes a convolution and will converge to a Gauss distribution (the central limit theorem for DP). We derive several relevant insights: we can now characterize mechanisms by their privacy loss class, i.e., by the Gauss distribution to which their PLD converges, which allows us to give novel ADP bounds for mechanisms based on their privacy loss class; we derive exact analytical guarantees for the approximate randomized response mechanism and an exact analytical and closed formula for the Gauss mechanism, that, given ε, calculates δ, s.t., the mechanism is (ε, δ)-ADP (not an over-approximating bound).
Correlation between Body Mass Index and Homa Index in Bariatric Patients
Authors: Dejeu Paula , Dejeu Viorel , Dejeu Dănuț , Marius Bembea
Published: May 2019

Background and aims: Overweight and obese individuals are prone to an insulin resistance status assessed in the present study by the HOMA index ("Homeostasis model assessment"). This prospective study assessed the body mass index (BMI) and the insulin resistance status (HOMA index) in obese patients after bariatric surgery (gastric sleeve, gastric by-pass).

Material and Methods: The study included 48 patients who were assessed before the bariatric surgery and at 6 months thereafter. The assessment included the body mass index (BMI) and the HOMA index before meal.

Results: There was a significant positive correlation between BMI and HOMA index, mostly between weight loss and improvement in insulin resistance status (rho = 0.308, p = 0.0335).

Conclusions: BMI decreases significantly after bariatric surgery, which correlates positively with an improvement in insulin resistance status.
Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats
Authors: Berroukeche Farid , Mokhtari-Soulimane Nassima , Imessaoudene Asmahan , Cherrak Ahmed Sabri , Ronot Pascale , Boos Anne , Belhandouz Amina , Merzouk Hafida , Elhabiri Mourad
Published: May 2019

Background and aims: Quercetin, is a polyphenolic antioxidant compound. It is able to form complex with metal ions such as iron and exerts a broad range of biological activities like improving metabolic disorders. This research aims at investigating the effect of oral supplementation of iron (2.5mg Fe/Kg/day) and its complex form (molar ratio 1:5; 2.5mg/25mg/Kg/day) with quercetin (25mg/Kg/day) on lipid metabolism, oxidant status and trace elements contents in organs of Wistar diabetic rats (45 mg/kg/rat.ip of streptozotocin) during eight weeks of experimentation.

Material and method: To achieve this, liver and adipose tissue enzymes activities, NO
•
, O2
−•
, TBARs, carbonyl protein levels in plasma were analysed. Metals (Cu, Fe, Mg, Zn) analysis of organs were determined by inductively coupled plasma atomic emission spectroscopy.

Results: Iron supplemented alone induced a noticeable disorder in lipid, lipoprotein, lipases and oxidant status. Yet, it caused an imbalance in the redistribution of metals in the organs of diabetic and non diabetic rats. Iron-quercetin complex was shown as less harmful and more beneficial than iron supplemented alone.

Conclusions: This complex could reverse oxidative stress and iron deficiency mostly caused by the diabetic disease but at the same time it induces an imbalance in redistribution of other essential metals.
The Relation Between Type 2 Diabetes Mellitus and Parkinson Disease Up to Date
Authors: Rasanu Irene
Published: May 2019

Parkinson’s disease is defined nowadays as a neurodegenerative disease with prominent motor symptoms accompanied by a wide range of comorbidities, some of them, like type 2 diabetes mellitus, probably implicated in the pathogenesis and progression of the disease. In order to achieve this article, which aimed to realize an up to date synthesis of published dedicated papers, a PubMed search was performed; it revealed increasing evidence that these two morbid conditions share many pathogenic pathways and current studies are trying to finally transform the accumulated knowledge into curative therapy or effective prevention for these frequent and complex diseases.
Comparison of microdebrider-assisted endoscopic sinus surgery and conventional endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps
Authors: Kaipuzha Ramiya Ramachandran , Venkataramanujam Nirmal Coumare , Karthikeyan Padmanabhan , Pulimoottil Davis Thomas
Published: May 2019

OBJECTIVE. To study and compare the benefits of microdebrider-assisted endoscopic sinus surgery and conventional endoscopic sinus surgery in terms of subjective and objective improvement in symptoms of nasal polyposis.

MATERIAL AND METHODS. This study involved 60 patients with bilateral sinonasal polyposis scheduled to undergo Endoscopic Sinus Surgery. The patients were randomized into two groups: Group A -Conventional endoscopic sinus surgery and Group B -Microdebrider-assisted endoscopic sinus surgery.

RESULTS. There was a significant difference in the mean VAS at 3 months postoperatively in Group B, but no significant difference at 6 months postoperatively following either of the two methods. The mean time for surgery (p<0.01) and the mean intraoperative blood loss (p<0.01) were significantly lower in Group B.

CONCLUSION. A well-trained surgeon with proper anatomical knowledge, good instruments, hypotensive anaesthesia, minimal mucosal injury and regular proper follow-up will have similar postoperative results with both methods.
Comparison results of nasal septum suturing and nasal packing following septoplasty
Authors: Peyvandi Ali Asghar , Oroei Mahbobeh , Khoshsirat Shahrokh
Published: May 2019

BACKGROUND. Septoplasty is routinely used to resolve the deviated nasal septum. To obviate postoperative complications, some surgeons pack both nasal cavities and some other use suturing techniques after septoplasty.

OBJECTIVE. To investigate the efficacy of septal suturing and packing in patients post-septoplasty.

MATERIAL AND METHODS. This study was conducted in the Department of Otorhinolaryngology, Loghman Hakim, Tehran, Iran. 146 patients aged 17 years and above were enrolled for septoplasty. Septal suture was performed in 73 patients (group A) and nasal packing in the other 73 patients (group B). The principal outcomes in terms of bleeding, pain, respiratory problems, septal hematoma, adhesion and perforation were measured over a post-operative follow-up period.

RESULTS. A total of 146 patients, 74% female and 26% male, were enrolled. There were statistically significant differences between the two groups with respect to respiratory problems and patient comfort (p<0.001). The patients in both groups had no septal perforation.

CONCLUSION. Septoplasty using trans-septal suturing without packing can be safe and suitable to prevent or minimize postoperative complications.
Point-of-care testing in diabetes management
Authors: Cozma Angela , Vonica Camelia , Sitar-Taut Adela , Fodor Adriana
Published: May 2019

The prevalence of diabetes mellitus (DM) has rapidly increased over the last decades, reaching epidemic magnitudes, particularly in lowand middle-income countries. Point-of-care (POC) technology enables decision making near or at the site of patient care. Portable blood glucose meters and HbA1c testing are used by the healthcare provider and millions of patients with diabetes to monitor the safety and effectiveness of the diabetes treatment. However, POC capillary blood glucose and POC HbA1c testing are not recommended for diabetes diagnosis. Rather, they have been used for screening diabetes in lowand middle-income countries to decrease the disease burden.
Simulation Model of Transport Traceability System for Transit Customs Goods within the EEU
Authors: Akhmedov Daulet , Yeryomin Denis , Zhaxygulova Dinara , Trepashko Sergey
Published: May 2019

This article reviews the transport traceability system for customs goods within the Eurasian Economic Union, which is the automated data system used to control integrity and movement of cargo section of a carrier vehicle by means of satellite navigation system, mobile cellular communication system and satellite communication system. Article is dedicated to the development of a model that simulates functions of transport traceability system for customs goods, which are being transported using the international transit transport corridors, and this model would be also used for assessment of a demand on electronic seals by seal installation stations, and for determination of correspondence between simulated transport route and actual travel time. Simulation model was already used in a test project, where it was integrated into “EVAC Transit” transport traceability system, and it has proven it’s operability and efficiency.