bluuebunny/crossref_metadata_2025 huggingface dataset:
A PRODUÇÃO DISCURSIVA DO REFÚGIO: NARRATIVAS, PERFORMATIVIDADE E IDEOLOGIAS LINGUÍSTICAS NO SISTEMA BRASILEIRO DE ELEGIBILIDADE
Authors: Biar Liana de Andrade , Castro Flávia Rodrigues de
Published: September 2024

RESUMO Neste artigo, refletimos, desde uma perspectiva discursiva, sobre o processo formal de elegibilidade de solicitantes de refúgio no Brasil. O objetivo central é sublinhar a dimensão performativa da produção do refugiado, aqui compreendido como um rótulo que depende de práticas discursivas - em especial narrativas -, de que participam os/as solicitantes, oficiais e demais atores sociais que compõem o sistema jurídico e burocrático do refúgio. Nessas práticas, o que parece estar em jogo são as competências narrativas do/a solicitante e entrevistadores/as em conformar a experiência de migração em uma matriz de inteligibilidades sobre o deslocamento humano e sobre o funcionamento da linguagem. A partir da análise de elementos de pelo menos duas importantes pontas do processo - textos de documentos normativos e entrevistas com voluntários que preparam solicitantes para suas entrevistas de elegibilidade -, mostramos como ideologias linguísticas, especialmente crenças sobre a natureza da construção narrativa, operam como protagonistas de tal processo institucional.
Desenvolvimento de um Modelo para Parametrização do Processo GMAW-P Aplicado a Manufatura Aditiva por Deposição a Arco
Authors: Coelho Fagner Guilherme Ferreira , Bracarense Alexandre Queiroz , Lima II Eduardo José , Arias Ariel Rodriguez
Published: September 2024

Resumo A fabricação de peças pelo processo de Manufatura Aditiva por Deposição a Arco (MADA) tem como característica o uso de fontes de soldagem aplicadas em GMAW, GTAW e PAW. O controle dos parâmetros durante a construção das peças é fundamental para contribuir com a redução do aporte térmico, possibilitando assim a aplicação de uma técnica para controlar o calor imposto sobre a deposição das camadas. O monitoramento do processo consiste em detectar variações no processo durante as deposições das camadas e vários são os recursos utilizados, tais como: emissão acústica, sistemas de visão computacional, sensores para coletar informações quanto à radiação térmica e/ou temperatura da peça, além da captura de informações quanto às variáveis elétricas. O objetivo deste trabalho é apresentar uma metodologia para o controle dos parâmetros durante a deposição das camadas de modo a atuar no equipamento por meio de um algoritmo de controle e um sistema de aquisição de dados, atuando no processo. Um estudo da influência dos parâmetros sobre a geometria e estabilidade de arco é apresentado. Um planejamento experimental baseado na técnica de Projeto Robusto foi aplicado para viabilizar o número de experimentos. Os resultados sugerem o efeito benéfico da duração do ciclo sobre a estabilidade do arco, comportamento da poça de fusão e geometria final.
MÚSICAS POPULARES NO ENSINO DE GENÉTICA E EVOLUÇÃO: RUPTURA DE ESTEREÓTIPOS E RACISMO CIENTÍFICO
Authors: Freitas Joana Lúcia Alexandre de
Published: September 2024

RESUMO: Este artigo apresenta uma reflexão sobre a importância da memória biocultural e das questões sociocientíficas para o ensino de genética e evolução. O objetivo é dialogar sobre a Memória Biocultural e contextualização do ensino de Genética e Evolução para destruição de preconceitos e estereótipos em relação à raça negra. Na metodologia, dentre os variados métodos de análise de conteúdo de Bardin, adotou-se a técnica de análise avaliativa para a interpretação de três canções que enaltecem e três músicas que são pejorativas ao povo negro. Dialoga-se sobre as diversas formas que o racismo científico se instaura no imaginário brasileiro e as implicações que as músicas pejorativas causam na vida em sociedade.
Turner syndrome and neuropsychological abnormalities: a review and case series
Authors: Guaraná Bruna Baierle , Nunes Marcela Rodrigues , Muniz Victória Feitosa , Diniz Bruna Lixinski , Nunes Maurício Rouvel , Böttcher Ana Kalise , Rosa Rafael Fabiano Machado , Mergener Rafaella , Zen Paulo Ricardo Gazzola
Published: September 2024

ABSTRACT Objective: The objective of this study was to establish the genotype-phenotype correlation between karyotype results and the neurological and psychiatric alterations presented in patients with Turner syndrome (TS). Methods: A retrospective study was conducted on the medical records of 10/140 patients with TS and neurophysiological abnormalities seen at a university hospital in southern Brazil. In addition, a literature review spanning the period from January 1, 2012 to January 1, 2023 was carried out using the PubMed and Virtual Health Library databases. Results: Our study showed a potential correlation between neurological and psychiatric alterations in patients with TS. These findings are in accordance with those described in literature such as a high prevalence of learning or intellectual disabilities. However, our sample found more seizure episodes than those reported in other studies. Conclusions: The correlation established could be due to X chromosome dose–effect, as the review suggests that sex chromosome number and hormonal development can be associated with verbal, social, and cognitive skills or impairments.
PRIVILÉGIO E AUTOIMAGEM DOS MILITARES DURANTE A PANDEMIA DE COVID-19 NO BRASIL: APOIO AO GOVERNO FEDERAL SOB O SACRIFÍCIO DA POPULAÇÃO BRASILEIRA
Authors: De Castro da Rocha José Pedro , Sampaio Wesley Sousa
Published: September 2024

A autoimagem supervalorizada dos militares brasileiros é moldada por sua formação e suas práticas simbólicas, que lhes garantem privilégios em relação aos civis. As Forças Armadas (FA), modernizadas sob um capitalismo dependente, enfrentam dilemas identitários que levam a intervir em questões como segurança pública e saúde, amparadas por uma Política Nacional de Defesa (PND) que vê ameaças tanto externas quanto internas. Durante a pandemia da Covid-19, as FA superaram o esforço com o Governo Federal (GF) ao apoiarem decisões que minimizaram a gravidade da crise sanitária, como a nomeação do general Pazuello ao Ministério da Saúde, que dinamicamente uma postura submissa às diretrizes negacionistas do presidente Bolsonaro, em contraste com seus antecessores. Além disso, o vice-presidente Mourão priorizou a alocação de recursos para a Força Aérea, mesmo após a crise dos respiradores em Manaus. Parentes de militares também foram implicados em fraudes relacionadas ao auxílio emergencial e ao atraso na compra de vacinas. A pesquisa qualitativa envolveu a análise de artigos acadêmicos, documentos jornalísticos e arquivos públicos, revelando que as FA optaram por manter seus privilégios e autoimagem, contribuindo para uma política que expõe a população ao risco de morte pela Covid-19. A pesquisa se insere nos Estudos de Defesa, evidenciando as relações entre civis e militares, a militarização da política e a intervenção militar contínua, que perpetuam interesses coloniais e impedem o desenvolvimento social independente do Brasil.
ESTRATÉGIAS PEDAGÓGICAS DESENVOLVIDAS POR ESTUDANTES DE ENFERMAGEM EM RESPOSTA À TEMÁTICA ÁLCOOL E OUTRAS DROGAS
Authors: De Paula Danielle Galdino , Alves Gabrielle da Silva Barreto , Ribeiro Raisa Duarte da Silva , Bilio Rafael de Lima
Published: September 2024

A necessidade de estratégias para o enfrentamento do uso abusivo de susbtâncias revela a urgência de reformular modelos assistenciais. O artigo relata a experiência pedagógica dos estudantes do curso de graduação em Enfermagem no desenvolvimento de saberes alinhados às necessidades dos usuários de álcool e outras drogas. Método: Relato de experiência que objetiva refletir sobre estratégias pedagógicas na formação de Enfermeiros. A população consistiu em 37 estudantes do segundo e terceiro períodos do curso de graduação em Enfermagem. As atividades foram desenvolvidas em três etapas principais: Participação em Ciclos de Debate; 2) Aulas com o tema Estratégias Pedagógicas e; Elaboração e Apresentação de Intervenções. Resultados: O desenvolvimento de estratégias pedagógicas pelos estudantes, revelou um esforço significativo para enfrentar os desafios associados ao uso abusivo de álcool e outras drogas. A escolha predominante por tecnologias digitais, como aplicativos e sites, destaca uma tendência crescente de incorporar recursos tecnológicos na educação e intervenção em saúde, refletindo a evolução das práticas pedagógicas e a adaptação às necessidades contemporâneas. Conclusão:A abordagem metodológica adotada, que incluiu a participação em ciclos de debate, a aplicação de metodologias ativas e o desenvolvimento de tecnologias digitais, evidenciou a capacidade dos discentes de criar soluções educacionais relevantes e adaptadas às necessidades contemporâneas.
MACHINE-LEARNED INFERENCE OF FRACTURE FLOWRATE FROM TEMPERATURE LOGS
Authors: Yang Xiaoyu , Horne Roland N. , Tartakovsky Daniel M.
Published: September 2024

Reliable identification of a fracture flowrate is essential to successful reservoir exploration and optimization. We developed a machine learning approach to identify fracture flowrate from spatiotemporal wellbore temperature measurements. A long short-term memory fully convolutional network was employed to jointly detect fractures intersecting the wellbore and quantify their contribution to the overall flow during fluid injection. Training data for the algorithm were generated by a wellbore and fractured-reservoir thermal model. The machine learning algorithm trained on single injectionstage temperature shows high fracture flowrate estimation accuracy on synthetic validation cases. It outperforms an optimization-based particle swarm optimization method on a real field case. For the machine learning method, the fusion of various-stage temperature as the input feature set improves the robustness of fracture detection and flowrate estimation to noise interference.
REVIEW ON CATALYTIC TREATMENT OF VOLATILE ORGANIC COMPOUNDS BY ZEOLITE-BASED HETEROGENEOUS CATALYSTS IN LIQUID AND GASEOUS MEDIUM
Authors: Hiader Syed Kamran , Dildar Aqsa , Shah Muhammad Naqi , Haider Syed Imran , Sheikh Tahir Ali , Islam Amjad , Haider Zeeshan , Ali Syed Ashar , Siddique Amna , Abbasi Muhammad Athar
Published: September 2024

Volatile organic compounds (VOCs) constitute a significant component of air pollutants, posing substantial risks
to both human health and the environment due to their toxicity, volatility, and diffusivity. Oxidative catalysis has emerged as a highly effective strategy for treating VOCs, and zeolite-based materials have proven to be efficient catalysts for such reactions. To date, zeolite-based materials are acknowledged as promising candidates for VOC oxidation, leveraging their meritorious properties, including unique structures, large surface areas, high adsorption capacity, uniform/intricate channels, high thermal stability, wettability, and well-defined micropores with excellent shape selectivity. This review comprehensively outlines the potential utility of zeolite-based catalysts, encompassing their types, adsorption, and catalysis mechanisms. Various research methods, such as adsorption-desorption, selective catalytic reduction, oxidation, isomerization, cracking, hydrogenation/dehydrogenation, peroxidation, and
photocatalysis, employed in zeolite-assisted catalysis of VOCs, are also discussed. Furthermore, the review delves
into the effects of feed gas composition, feed gas flow rate, reaction temperature, and zeolite type on the catalytic process.
WIDEBAND ABSORBANCE PATTERNS IN ADULTS WITH CENTRAL AND MARGINAL TYMPANIC MEMBRANE PERFORATION
Authors: Ashokganesh Sairaman Thangam , Barman Animesh , Karuppannan Arunraj
Published: September 2024

Introduction

This study aimed to investigate the impact of central and marginal tympanic membrane perforations (TMP) on wideband absorbance (WBA) and compare it with normal ears.

Material and methods

Three groups of individuals, aged 18 to 50 years: Group I with central TMP (n = 65), Group II with marginal TMP (n = 13), and Group III with normal middle ears (n = 20) were considered. WBA measurements were performed at peak and ambient pressure conditions across frequencies.

Results

Significant differences in WBA were observed between the groups with central and marginal TMP and the normal ear group across all frequencies. Central TMP exhibited decreased absorbance at low frequencies and increased absorbance at high frequencies, peaking at 5000 Hz. Marginal TMP showed peaks at 600, 4000, and 6000 Hz with decreased absorbance at 2000 Hz. Central TMP exhibited lower absorbance than marginal TMP at lower frequencies, while marginal TMP showed decreased absorbance at mid and high frequencies.

Conclusions

These findings highlight the role of WBA in differentiating normal ears from those with TMP. Understanding TM vibration patterns and frequency-dependent variations in absorbance enhances diagnostic accuracy and clinical management.
Mechanical properties of eco-friendly self-compacting concrete made from partially replaced single-use waste plastic and complete recycled coarse aggregate using RSM and ANN methods
Authors:   Department of Civil Engineering, Om Sterling global University, Hisar, Haryana, India, Suvidha Suvidha , Jain Sumesh ,   Department of Civil Engineering, Om Sterling global University, Hisar, Haryana, India, Kumar C. Arvind ,   Department of Civil Engineering, Matrusri Engineering College, Hyderabad, Telangana, India
Published: September 2024

The paper aims to use most of the recycled material from the waste and develop a sustainable Eco-Friendly Self-Compacting Concrete (EF-SCC). Two different plastic wastes, High-Density Polyethylene (HDPE) and Polypropylene (PP), were collected from the dumping yard, thoroughly cleaned, and shredded into the desired shape and size. The plastic was substituted with fine aggregate (FA) in amounts ranging from 5% to 20%, with a 5% rise in each mix. The recycled coarse aggregate was obtained by breaking the concrete cubes, beams, and cylinders available for testing at the concrete technology lab. Totally 4 mixes were prepared for M40 grade EF-SCC to determine the mechanical property at 4 different ages (7, 14, 28 and 56 days). The compressive strength results were then predicted using statistical tools such as RSM and ANN. It is observed that both HDPE and PP have workability in the range of 650mm to 800mm, which is acceptable according to EFNARC 2002. The RSM method yielded 99.69% for PP material, while HDPE had 98.17%. The optimum compressive strength values were achieved at 7.5% of HDPE and 5% of PP material at 28 days and 60 days of curing. The training, validation, Test, and All values of R for M40 grade concrete for HDPE and PP material were 0.9955, 0.9980, 0.9244, 0.9241, and 1, 0.972, 0.802, 0.972 respectively. The flexural strength of EF-SCC showed the best results at 15% replacement. The prediction of actual compressive strength with RSM was more accurate for HDPE material compared to ANN. Recycled aggregate showed positive signs in using waste material in construction industries.
Processing and properties of Ti-15Zr-15Mo-(1-3)Ag alloys for applications as biofunctional materials
Authors: Torrento Jhuliene Elen , Grandini Carlos Roberto , Nespeque Correa Diego Rafael
Published: September 2024

Titanium (Ti) is employed as a biomaterial because of its superior biocompatibility and favorable mechanical properties that can be changed with the addition of alloying elements, such as zirconium and molybdenum. Silver is an alloying element recognized for its antibacterial action, which can improve the mechanical strength and decrease Young’s modulus of Ti. This work studies the effect of silver addition (1 and 3 wt%) on the crystalline structure, microstructure, Vickers microhardness and Young’s modulus of Ti-15Zr-15Mo (wt%) alloy, targeting for a potential application as a biofunctional material. The ingots were produced by argon arc melting and subsequently subjected to a heat treatment of homogenization, hot-rolling and solubilization heat treatment. Chemical composition indicated good quality on the processing of the alloy. Crystalline structure and microstructure analyzed by X-ray diffraction, optical microscopy and scanning electron microscopy showed only titanium’s β phase. Finally, mechanical properties studied by Vickers microhardness and Young’s modulus measurements presented that the addition of low content of silver did not significantly modify the alloy’s mechanical properties, but it can include antibacterial properties on the bulk.
Structure proposed to deal with sensor-based data
Authors: Colevati dos Santos Leandro , Gomes dos Santos Filho Sebastião , Pereira da Silva Maria Lucia
Published: September 2024

The possibility of greater control over processes, with the increasing use of sensors, leads to the generation of a large amount of data and, consequently, inherent difficulties, also need care. Storage, processing, filtering, become more difficult and the use of cloud computing can be a solution, however, the cloud computing technology also has limitations regarding latency and availability that can be mitigated with the use of an intermediate layer, called fog computing. As the structuring of the fog computing layer is not yet standardized, one of the possibilities is the application of an enterprise service bus (ESB), a structure based on the availability and interconnection of targeted services, for processing, filtering or storage. From an ESB structure such as fog computing, proofs of concept were developed to validate the technology, the first proof of concept being an environment, whose temperature must be controlled, with distributed sensors and their values received, processed and stored by services in the ESB and the second proof of concept, based on soil contaminant data, obtained by sensors and made available in the literature, for which filtering and processing services, on the same bus, were used. The study presents, in its results, the applicability of the fog computing layer, minimizing the limitations of cloud computing.
Encapsulation method developed for OLED devices mounted at laboratory
Authors: Santos Emerson Roberto , Yuki Erik Yassuo , Hui Wang Shu
Published: September 2024

A simple method with low cost of encapsulation for organic light emitting diode (OLED) devices mounted at laboratory was proposed to obtain considerable increase of the lifetime. In this study, it was used a capsule formed by: glass slide as substrate, a layer of polyvinyl acetate glue diluted in methyl alcohol, a layer of calcium oxide as secant and epoxy placed at the edges of capsule. The performance of this capsule was analyzed using a thin film of polymer semiconductor called as PEDOT:PSS, that is sensitive to moisture and oxygen from atmospheric air. The PEDOT:PSS thin layer was deposited between anode and cathode electrodes using commercial indium tin oxide (ITO) thin film deposited on glass substrate. The capsule was placed covering completely the PEDOT:PSS thin film, and the electrical resistance was measured by elapsed days. This result revealed lowest electrical resistance compared with other methods, showing also good performance as encapsulation process.
Análise de dados de um espectrômetro óptico
Authors: Cipriano Rangel Rita de Cassia , Darbello Sabrina Moretto , SantAna Péricles Lopes
Published: September 2024

Um espectrômetro óptico é um equipamento capaz de determinar as características de filmes finos, tais como espessura e constantes ópticas, pela sua interação com a luz. As constantes ópticas descrevem como a luz é refletida ou se propaga através de um material. Neste trabalho, utilizou-se um espectrômetro óptico portátil (Ocean Optics USB 4000), com o objetivo de analisar a curva de transmitância óptica em função do comprimento de onda de um filme fino de carbono amorfo hidrogenado. Esse filme possui alta transmitância na região próxima a 800 nm e baixa transmitância para comprimentos de onda abaixo de 400 nm. O índice de refração encontrado (ns) foi de 1,513, e a espessura do filme depositado (h), de 2.369 nm.
Systematization and justification of recreational mechanisms of laughter in the system of personality
Authors:   Odesa National Maritime University, Odesa, Ukraine, IVANOVA Olena
Published: September 2024

B a c k g r o u n d . A theoretical and methodological analysis of approaches to recreational laughter mechanisms is presented. Laughter is regarded as an individual psycho-physiological reaction to a certain unexpected situation that is formed based on emotionally colored personal senses and value ideas, shown in various expressions of joy. M e t h o d s . Given the multilevel phenomenon, the mechanisms of its influence on the individual are analyzed in the context of philosophical, theological, cultural, pedagogical, psychophysiological, and psychological (social) approaches. Theoretical research methods were used: analysis of scientific sources on the research topic, system analysis, synthesis, generalization of scientific approaches, classification and specification of laughter mechanisms in the personality system. R e s u l t s . In the context of the restorative mechanisms of laughter, its connection with direct play and joy arising in the process and accompanied by release, relief, satisfaction, and relaxation, helping to go beyond the ordinary, is considered. It has been revealed that laughter is also one of the ways for the soul to realize and liberate itself through release from fears and mental tension. It has also been proven that laughter serves as a certain stimulator of brain activity, activates imagination and fantasy, that is, promotes creativity. It is substantiated that laughter is a necessary element of stress relief, has a restorative and regenerative effect on the physical and psycho-emotional state, acts on the physiological and hormonal levels, activates the frontal, motor lobes, brain stem and cortex, hippocampus, thalamus and limbic system. It is argued that during laughter a spastic effect is realized, it affects the regulation of breathing, unites the physical and mental principle. C o n c l u s i o n s . It was determined that laughter, as an important personal resource of interaction with other people, plays a special role in the prevention and correction of unwanted stress states of the individual. It has been found that it greatly helps a person to adapt to various unexpected situations, because laughter unites people, helps to free oneself from the influence of fears, anxieties and doubts and allows to manifest the true qualities laid down from birth, such as love, clarity of perception, compassion, joy, enthusiasm, gratitude and wisdom. Laughter can help you make good decisions and show kindness in your actions.
The influence of rehabilitation on the quality of life after radical treatment of endometrial cancer and atypical endometrial hyperplasia
Authors: Sandzhieva L. N. , Galkin V. N. , Blinov D. V. , Solopova A. G.
Published: September 2024

Background. Gynecological cancers in women are a widespread type of oncology. Among them, endometrial cancer (EC) is often highlighted as one of the most common diseases in this group. The analysis of publications showed insufficient effectiveness of rehabilitation in patients with EC and recurrent atypical endometrial hyperplasia (rAEH).

Objective: to compare the state of patients with rAEH or EC after hysterectomy with bilateral salpingo-oophorectomy, depending on the recovery tactics.

Material and methods. The study included 119 patients diagnosed with rAEH (n=58) or stage IA EC (n=61) after hysterectomy with bilateral salpingo-oophorectomy. The group of women with rAEH was divided into two subgroups: 1A (“active” rehabilitation, n=27) and 1B (“passive” rehabilitation, n=31); two subgroups were also formed from the cohort of EC patients: 2A (“active” rehabilitation, n=29) and 2B (“passive” rehabilitation, n=32). “Active’ rehabilitation included a comprehensive, personalized program, “passive” one was based on standard rehabilitation protocols. Apart from standard clinical examination of patients, their quality of life (QoL), physical condition as well as the levels of cytokines and other biochemical blood parameters were assessed.

Results. An analysis of the overall picture showed a high incidence of rAEH or EC in women aged 40–49 years. Comorbid pathologies, low QoL level and a number of significant changes in laboratory parameters were often observed. Regardless of the approach to rehabilitation, the patients' health improved over the course of 12 months. “Active” rehabilitation significantly improved psychological well-being, sexual function, overall QoL and a number of other objective health indicators of patients with rAEH or EC compared to standard rehabilitation course.

Conclusion. The overall picture of rAEH or EC patients was presented, the main factors that reduce QoL in women with these diseases were identified. A system of integral QoL assessment in patients with rAEH or stage IA EC was developed including subjective and objective parameters obtained during general clinical examination, laboratory tests and analysis of questionnairing results, which should be used to adequately monitor the state of patients after surgery and the effectiveness of rehabilitation. The advantage of comprehensive rehabilitation over standard protocols in terms of efficiency and speed of recovery was shown.
The role of epigenetics in the diagnosis, treatment and rehabilitation of patients with malignant neoplasms
Authors: Vlasina A. Yu. , Begovich E.
Published: September 2024

Background. Epigenetics is a branch of genetics that studies the influence of external factors on gene expression. Many studies have shown the role of epigenetic regulation mechanisms in gene expression, including patients with cancer. Despite the clear prospects of using the principles and methods of epigenetics in the diagnosis, treatment and recovery, the implementation of this new technology remains at a relatively low level.

Objective: to determine the importance of epigenetic mechanisms in the diagnosis, outcome prognosis and rehabilitation of patients with oncological diseases.

Material and methods. The search for publications was performed in scientific databases and electronic libraries: PubMed/ MEDLINE, ScienceDirect, Google Schoolar, eLibrary. The review included 79 articles on the role of epigenetic mechanisms in the diagnosis, treatment and rehabilitation of cancer patients.

Results. DNA methylation, covalent histone modifications, and microRNA regulation are the most studied epigenetic changes (EGC) in cancer patients. Liquid biopsy is alternative approach to the detection of epigenetic biomarkers. A number of biomarkers were identified that make it possible to diagnose oncological diseases, e.g. lung cancer and breast cancer, and predict their course. Some EGC were assosiated with the implementation of rehabilitation measures, such as nutritional support, physical activity, maintaining circadian rhythms and acupuncture.

Conslusion. The analysis of publications confirmed the significant importance of EGC on the development of malignant neoplasms. The results indicated a sufficient number of studies dedicated to EGC biomarkers as new diagnostic tools and predicting the oncological disease outcome. But there is an insufficient number of studies on EGC mechanisms in rehabilitation. Further investigation on epigenetic mechanisms of variability will allow making significant progress in the development of targeted drugs and personalized rehabilitation of patients with malignant neoplasms.
Rehabilitation of oncological patients: a comparative analysis of clinical guidelines for managing oncological patients with renal parenchyma cancer, bladder cancer and female cancer in Russia, Europe, and USA
Authors: Petrenko D. A. , Aleksandrov A. G.
Published: September 2024

Backround. Current medicine pays significant attention to an integrated approach in managing cancer patients, from the stage of diagnosis to rehabilitation. Sections on rehabilitation have been added to respective guidelines to maintain the proper quality of life of patients and standardization of clinical protocols. Due to the different levels of medicine in Europe, Russia and USA, it is important to analyze guidelines for supporting oncological patients at the rehabilitation stage.

Objective: to conduct a comparative analysis of guidelines for managing cancer patients.

Material and methods. The search and selection of publications were performed according to PRISMA recommendations. In scientific databases PubMed/MEDLINE, Google Scholar, ScienceDirect, eLibrary as well as via search engines and the Rubricator of Clinical Guidelines of the Ministry of Health of Russia, 725 sources were found. After the selection procedure, 30 publications and guidelines were included in the review.

Results. Rehabilitation programs are presented in many Russian, American and European guidelines for the support of cancer patients. In Russian guidelines for managing patients with renal parenchyma and bladder cancer, a significant emphasis is made on the pre-rehabilitation and using fast-track approach. A lot of attention is paid to therapeutic physical culture and instrumental methods. American and European guidelines are more detailed, in particular, protocols for the correction of certain adverse events are presented, psychological assistance and complex rehabilitation play an essential role. The absence of specialized rehabilitation program in Russian clinical guidelines for supporting oncogynecological patients, and universal character of protocols were noted. According to foreign guidelines, the rehabilitation of such patients is multidisciplinary and personalized, and is carried out in specialized centers.

Conclusion. The review showed a number of deficiencies in Russian clinical guidelines. In certain documents, due attention is not paid to the provision of rehabilitation. It’s necessary to expand multidisciplinary approach in cancer patients' rehabilitation as well as the evidence base to improve Russian guidelines.
Methods for assessing quality of life in cancer
Authors: Petrenko D. A. , Korabelnikov D. I.
Published: September 2024

Background. The problem of a significant reduction in the quality of life (QoL) of oncological patients remains relevant despite current achievements in medicine. The issue of standardizing methods for assessing QoL in such patients is relatively acute. Patients undergo this assessment from the diagnostic stage to the end of rehabilitation, so it’s important to choose an accurate and precise method for QoL evaluation.

Objective: to analyze existing questionnaire-based methods for assessing QoL in cancer patients.

Material and methods. The search for publications was conducted in the scientific databases PubMed/MEDLINE, ScienceDirect, and eLibrary. Additionally, the sources found by queries in Yandex and Google search engines by each researcher individually were considered. The review included 38 articles.

Results. The vast majority of questionnaires used to assess QoL in oncological patients can be divided into two large groups: based on QLQ-C30 and FACT-G. Despite the similarity between QLQ-C30 and FACT-G questionnaires, some shift in their focus was shown. QLQ-C30 is more oriented on physical indicators, and FACT-G is more aimed at social and emotional well-being. Besides them, questionnaires that proved to identify and monitor individual groups of symptoms and syndromes were presented: FSFI, HADS and Russian questionnaire on well-being, activity, mood.

Conclusion. The obtained results indicated a fairly wide choice of questionnaires for the overall assessment of QoL and its individual elements. They include both proven screening and monitoring tools and those requiring validation and expansion of the evidence base. Due to high effectiveness of questionnaires as QoL screening and monitoring tools, further work is needed to ensure that they are widely included in clinical guidelines.
Analysis of legislative basis for medical rehabilitation in Russia
Authors: Voynovskiy A. E. , Efanov A. E.
Published: September 2024

Background. In recent years, there have been significant changes in the regulatory documentation related to medical rehabilitation, caused by the need to consolidate the principles for rehabilitation of patients in post-COVID period and standardize the procedures used for it. Therefore, it is important to analyze the existing regulatory framework and the proposed changes that will come into force in the near future.

Objective: to assess the regulatory legal acts governing the provision of medical rehabilitation in Russia.

Material and methods. Regulatory legal acts and their drafts were obtained through the reference and legal systems “Kontur Standard”, “ConsultantPlus”, and the Federal Portal of Draft Regulatory Legal Acts. The following electronic libraries, databases and other sources were used to collect secondary information: eLibrary, Google Scholar, PubMed/MEDLINE, Yandex and social networks.

Results. Article 41 of the Constitution of the Russian Federation guarantees the right to health protection and medical care. Within the latter the use of medical rehabilitation can be considered. Going down to the next level, the term “medical rehabilitation” is found in Federal Law dated November 27, 2011 No. 323-FZ “On the fundamentals of health protection of citizens in the Russian Federation”. However, the requirements in the field under consideration are specifically described in Orders of the Ministry of Health of Russia No. 788n and 878n, which establish a three-stage provision of medical rehabilitation and give specific time instructions for the frequency and duration of care prcedures. The conditions for the transition of patients between the stages of medical rehabilitation are presented, and creating interdisciplinary rehabilitation teams is specified.

Conclusion. The analysis of innovations in the regulatory framework showed no fundamental changes in the regulation of medical rehabilitation. At the moment, there is a need to expand it by regulating the activities of multidisciplinary rehabilitation teams. A more detailed elaboration of normative documentation regulating the provision of medical rehabilitation to children is necessary.
Антимиф «о святом великомученике царе Николае II» и годах его правления
Authors: Ильинский Игорь Михайлович
Published: September 2024

В статье исследуется личность и политическая деятельность последнего российского императора Николая II. Цель автора — развенчать миф о Николае II как о добродетельном правителе, приведшем страну к процветанию, но мученически погибшем от рук большевиков. Как показывает автор, в действительности российский император был человеком слабовольным, от природы не способным управлять государством. В статье воссоздается психологический портрет Николая II, подробно рассматриваются особенности его внутренней и внешней политики. Показано, что в целом империя при этом государе вовсе не находилась в зените своего экономического и политического могущества. Поэтому падение дома Романовых в каком-то смысле имело закономерный характер.
Феномен виртуализации ислама (на примере Индонезии)
Authors: Кирчанов Максим Валерьевич
Published: September 2024

В статье анализируются особенности и направления процессов виртуализации и цифровизации ислама в современной Индонезии. Показано, что процессы интеграции ислама в виртуальные пространства начались в 2000-е гг. Показано, что виртуализация ислама отличалась постепенным характером. Автор демонстрирует, что цифровизация имела несколько форм, включая развитие сайтов мусульманских организаций и их аккаунтов в социальных сетях и на видеохостинговых платформах. Анализируется вклад и участие умеренных и радикальных сторонников политического ислама в его постепенной виртуализации. Утверждается, что глобальная пандемия новой коронавирусной инфекции стала тем фактором, который заставил индонезийских мусульман активизировать свою деятельность и увеличить представленность мусульманских организаций в виртуальном пространстве. B статье показаны основные векторы и траектории виртуализации и цифровизации ислама в Индонезии. Автор анализирует ранний этап виртуализации, особенности процессов цифровизации и роль пандемии в активизации виртуализационных процессов. Исследуются различные точки зрения и мнения, высказанные мусульманскими интеллектуалами в Индонезии в контекстах дебатов о возможности или недопустимости совершения намаза онлайн. В целом в представленной статье показано, что тенденции цифровизации ислама в современном индонезийском обществе стали фактически неизбежными, актуализируя тенденции фрагментации мусульманской общины.
Воспитание патриотизма средствами английского языка у студентов физкультурных специальностей
Authors: Золотова Марина Вианоровна , Ганюшкина Елена Валентиновна , Лунина Вера Леонтьевна
Published: September 2024

В свете последних внешнеполитических событий воспитание патриотизма среди молодежи представляется первоочередной задачей. Для ее решения были введены специальные учебные курсы как в рамках общеобразовательной школы и учреждений среднего профессионального образования (курс «Разговоры о важном»), так и высших учебных заведений (курс «Основы российской государственности»). Однако работа по воспитанию патриотизма представляется значительно более эффективной только в случае междисциплинарного подхода к решению данной задачи. Работа по воспитанию патриотизма со студентами факультетов физической культуры и спорта имеет свою специфику. В данной статье рассматривается возможность использовать в работе на уроках иностранного языка тексты, связанные с развитием спорта в России, посвященные старинным русским спортивным играм и изучению жизненного пути спортсменов, прославивших Россию, но, к сожалению, оставшихся малоизвестными для современного поколения, а также первым победам российских спортсменов на возрожденных в XIX в. Олимпийских играх.
Experience of abrocitinib in atopic dermatitis
Authors: Kochergin Nikolay G. , Abdulridha Ali H. , Myzina Kristina A.
Published: September 2024

Atopic dermatitis is an autoinflammatory, genetically determined, itchy disease characterized by a long, relapsing course and a sharp decrease in the patient’s quality of life. Atopic dermatitis is caused by a complex interaction of immune dysregulation, epidermal gene mutations, and multi-environmental factors that affect the skin, causing intense itchy rashes. The disease often occurs among young children and subsequently has age-related clinical features.
Currently, the treatment of atopic dermatitis has a wide range of options, including drugs from the group of small molecules recently registered in the Russian Federation. The drugs are intended for patients with moderate to severe atopic dermatitis. Baricitinib, abrocitinib and upadacitinib as Janus kinase inhibitors from the small molecule group have already demonstrated good tolerability, safety and a pronounced clinical effect in the vast majority of patients with atopic dermatitis in available clinical trials.
The first clinical experience with the use of abrocitinib in adult patients with atopic dermatitis is presented. The interest of the presented clinical cases lies in the demonstration of high clinical efficacy and safety of mono- and combination therapy with the Janus kinase inhibitor abrocitinib. Despite the short period of treatment and observation (4 weeks), objective severity of atopic dermatitis manifestations (SCORAD index 60 points) and sharp decrease in the patients' quality of life (DLQI index 20 points), a reduction of clinical parameters exceeding 60% was achieved at a dose of 200 mg daily. During the whole observation period no adverse clinical reactions or changes in laboratory parameters were registered against the background of abrocitinib administration.
The pilot results of abrocitinib use are encouraging and provide grounds for conducting longer and larger-scale studies to investigate the efficacy of the drug for its inclusion in the combination therapy of patients with moderate to severe atopic dermatitis.
Poly-L-lactic acid in the correction of age-related changes in facial skin
Authors: Snarskaya Elena S. , Churbanova Anastasia I.
Published: September 2024

Age-related changes in the skin of the face and neck are the result of a number of interrelated biochemical processes occurring in various tissues (dermis and epidermis, subcutaneous fat, musculoskeletal apparatus and bone tissue). Currently, there are a number of minimally invasive techniques to correct age-related changes in the skin of the face, but the discussion regarding the clinical efficacy and duration of retention of the effect in correcting age-related facial changes continues.
Poly-L-lactic acid (PLLA) is popular with specialists and is used as an effective method of correcting involutive changes in the skin of the face, however, despite the extensive experience of its use, there is not enough research in foreign and domestic literature to study the duration of retention of the effect of drugs based on poly-L-lactic acid.
The article presents an analysis of the data of modern literature devoted to the study of the effectiveness of the use of poly-L-lactic acid as a method of correcting age-related changes in the skin of the face.
On the issue of the syndromic forms of pyoderma gangrenosum
Authors: Olisova Olga Yu. , Grabovskaya Olga V. , Teplyuk Natalia P. , Bobkova Anna E. , Tavitova Alana R. , Kusraeva Diana T. , Myshlyanova Diana A.
Published: September 2024

Gangrenous pyoderma is an autoinflammatory polygenic neutrophilic dermatosis characterized by the formation of painful ulcerative skin defects with boldly raised undercut edges of purplish-cyanotic coloration and an erythema zone around the focus.
Gangrenous pyoderma can manifest as an isolated dermatosis, and be associated with various autoinflammatory syndromes: PASH (gangrenous pyoderma, conglobate acne and purulent hydradenitis), PAPA (gangrenous pyoderma, pyogenic arthritis and conglobate acne), PAPASH (gangrenous pyoderma, pyogenic arthritis, conglobate acne and purulent hydradenitis), PAPASC (gangrenous pyoderma, pyogenic arthritis, conglobate acne, purulent hydradenitis and ulcerative colitis), etc.
A number of genetic mutations have been found in the syndromic forms of gangrenous pyoderma (MEFV, NOD2, LPIN2, NLRP3, NLRP12, PSMB8, MVK, IL1RN, PSTPIP1) affecting inflammatory regulatory proteins, which contributes to the development of an autoaggressive process. Neutrophilic autoinflammatory syndromes have a common pathogenesis mechanism, which is an excessive activation of the innate link of the immune system, with hyperproduction of proinflammatory IL-1, IL-17 and chemokines, leading to aseptic neutrophilic inflammation of the skin.
At the moment, the treatment of syndromic conditions remains a difficult task. Systemic glucocorticosteroids, immunosuppressants, antimetabolites, and sulfone preparations are used in complex therapy, however, more and more studies indicate the possibility of therapy with genetically engineered biological drugs with TNF inhibitors, IL-1 and IL-17.
We present two clinical observations of rare forms of autoinflammatory neutrophilic syndromic conditions PASH and PAPASC in patients aged 20 and 21 years.
Application of a semi-empirical modelling approach to a Two-Stage
Rotary CO2 compressor
Authors: Vega Javier , Cuevas Cristian , Dickes Rémi , Lemort Vincent
Published: September 2024

2-stage Rotary CO2 compressors are currently in use in refrigeration and heat pump applications, including occasionally including vapour injection. The need of correctly assessing the compressor’s efficiency by means of a computationally fast model arises for cycle performance prediction and optimization. In response, an innovation on an existing semi-empirical modelling approach has been introduced in this paper to describe 2-stage Rotary compressors. The model has been validated with experimental data of a CO2 compressor available in open literature, giving maximum errors of around ±3% for mass flow and ±1.82% for power prediction. Calibration of a simplified 1-stage model is also performed to analyse to which extent it is necessary to complexify the model, and to identify key or neglectable modelling elements. It is found that doing this increases the error of the compressor performance prediction. Model analysis has been done to identify the inefficiencies introduced by each physical effect considered.
Social assessment of the population for the transition to value-based healthcare model
Authors: Shkarin Vladimir V. , Donika Alena D.
Published: September 2024

BACKGROUND: The advanced experience of implementing a value-based model in the practice of Moscow healthcare allowed us to identify a number of the most significant practices of its effectiveness, among which support for making an informed decision by the patient, as well as measuring satisfaction and analyzing the needs of patients were noted. In this regard, the transition of the entire national healthcare system to a value-based model requires the development of approaches to assessing the population’s compliance with such a transformation, taking into account socio-economic, demographic and psychological criteria.
AIM: To consider possible predictors of the readiness of a social group of the population older than working age to transition to a value-based model of national health care.
METHODS: A review of fundamental and modern works in the problem field was carried out. The empirical basis of the work was made up of data from the official website of the Federal Statistics Service with geographic coverage of the entire Russian Federation.
RESULTS: Analysis of data from a subjective assessment of the population's health on a national sample demonstrates the internal readiness of the population for a value-based healthcare model, despite the negative trends of aging. In age groups over 55, the majority of respondents rated it as «satisfactory», with the number of «very bad» ratings being minimal. Positive dynamics in the formation of information technology competence in the population over 65, who are experiencing difficulties in integrating into digital healthcare services, are shown. The positive dynamics of the formation of information technology competence of the population over 65 years of age, who are experiencing difficulties in integrating into digital health services, is shown.
CONCLUSION: The transition of national healthcare to a value-oriented model involves active patient involvement and the formation of patient experience in assessing the results of medical care. In this regard, it is necessary to take into account the personal socio-psychological profile of patient compliance, as possible modules of which the work demonstrates the use of subjective health assessment and assessment of the information technology competencies in the social group of people over working age, the growth of whose numbers determines demographic realities.