bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship Between Family Support and Family Stress in Pulmonary Tuberculosis Patients
Authors: Suarnianti Suarnianti , Haskas Yusran , BN Indah Restika
Published: January 2024

Pulmonary tuberculosis is the third most prevalent disease worldwide. It is a contagious disease caused by Mycobacterium tuberculosis, a bacterium characterized by dimensions of 0,5-4µ x 0,3-0,6µ and an outer thick layer composed of lipids that are resistant to chemical penetration. Family support is one of the factors influencing the treatment of pulmonary tuberculosis, where both main and extended family serve as a support system for their affected members. The primary function of a family is to provide healthcare. The objective of this study is to investigate the relationship between family support and family stress among pulmonary tuberculosis patients at Tamalanrea Primary Health Center. This study employed a quantitative cross-sectional research design and utilized a total sampling approach with a sample size of 32 patients. Data were collected through questionnaires and analyzed using Fisher’s Exact test. The results of the study revealed a significant relationship between family support and family stress in tuberculosis patients, with a p-value of 0,018. In conclusion, this study established a correlation between family support and family stress among pulmonary tuberculosis patients at Tamalanrea Primary Health Center. It is suggested that future researchers use larger sample sizes to explore additional factors that impact family support and family stress among tuberculosis patients.
Analysis of Contact Dermatitis Incidence Factors in Fishermen in The Working Area of Wapunto Health Center
Authors: L. Titi Saparina , Sya’ban Abdul Rahim , Kasih Ridia Utami , Ali Leniarti , Solihin Solihin , Firmansyah Firmansyah
Published: January 2024

The prevalence of contact dermatitis in the Working Area of Wapunto Public Health Center, increases yearly, that is, in 2018 was 22.3% per 1000 population, in 2019, was 29.4% in 2020, was 35.2%. The purpose of this study was to determine the factors related to contact dermatitis disease in fishermen in the Working Area of Wapunto Public Health Center, Muna Regency. The type of study was observational quantitative with a cross-sectional study design. The total population in this study were 255 families, while the sample was 72 respondents using cluster random sampling. Data analysis using chi-square test. The results of the study showed that there was a relationship between contact time with value X2count > X2table, namely 19,412 > 3,481, personal hygiene with value X2count > X2table namely 26,331 > 3,481, history of allergies with value X2count > X2table, namely 11,250 > 3,481, use of PPE with value X2count > X2table namely 31,065 > 3,481 with contact dermatitis disease in fishermen in the Working Area of Wapunto Public Health Center, Muna Regency. In conclusion, there is a relationship between contact time, personal hygiene, history of allergies, and PPE use. Therefore, fishermen should reduce the risk or prevent the incidence of contact dermatitis by further improving personal hygiene, such as washing hands and feet using soap, changing work clothes and using clean and not humid PPE.
Management Analysis of Early Initiation of Breastfeeding in The New Habit Era
Authors: Trianingsih Indah , Marlina Marlina , Sari Adinda Juwita
Published: January 2024

There are still a number of Independent Midwives who have not implemented the early initiation of breastfeeding management in the New Normal Era. As early as 2020, newborns should be separated from their Covid-19 infected mothers. This study aims to analyze the management of the early initiation of breastfeeding in the New Normal Era from the point of view of the midwives' knowledge and the relationship between Midwives' knowledge and the implementation of the early initiation of breastfeeding in the New Normal Era. The research method used is quantitative analysis with a cross-sectional design. The design of this study is quantitative analytic with a cross-sectional research design. The population was all Operative Independent Midwives in East Tanjungkarang District of Bandar Lampung City, which amounted to 42 people, and the entire population was sampled. Data analysis used frequency distribution and bivariate analysis using chi-square. Based on the research results from 42 respondents, most had good knowledge about the early initiation of breastfeeding in the new habit era of 29 people (69%), and most midwives had implemented the early initiation of breastfeeding by complying with the Covid-19 protocol, of which 28 people (66.7%). The results of the chi-square analysis obtained a p-value of 0.015, which shows a relationship between midwives' knowledge of the suitability of the early initiation of breastfeeding implementation and the Covid-19 protocol in the New Habit Era of 2022. It is expected that midwives can consistently increase their knowledge and follow the overall developments as the health workers who play a role in the implementation of the early initiation of breastfeeding so that they can implement the early initiation of breastfeeding following the management of newborns babies in Indonesia as a first step to succeeding in exclusive breastfeeding.
Stress Factors and Macronutrient Intake to Total Cholesterol Levels and HDL Levels in Overweight Female Students
Authors: Damayanti Amilia Yuni , Fathimah Fathimah , Sari Atika Rahma , Pibriyanti Kartika
Published: January 2024

Being overweight is one of the many health problems that occur in modern times. Stress and macronutrient intake are factors that can affect the occurrence of increased cholesterol levels and decreased HDL in overweight. This study aimed to determine the relationship between stress factors and macronutrient intake on cholesterol and HDL levels. This research uses a cross-sectional design with a purposive sampling method, namely selecting subjects with certain criteria. The number of subjects was 50 Overweight female students based on the population proportion sample formula calculation. Stress data was measured using the Depression, Anxiety, and Stress Scale (DASS 42) questionnaire and macronutrient intake data using a 24-hour food recall form. Data analysis using the Chi-square test. The results obtained stated that 30% of respondents had high cholesterol levels, 2% of respondents had low HDL levels. As many as 22% of respondents experienced stress, the carbohydrate intake of 80% of respondents was inadequate, the protein intake of 96% of respondents was inadequate, the fat intake of 96% of respondents was inadequate. Analysis of the relationship between stress and total cholesterol (p=0.152), carbohydrate intake (p=0.416), protein (p=0.331) fat (p=0.669) with total cholesterol levels, carbohydrate intake (p=0.080) protein (0.960) fat (0.960 ) with HDL levels. Stress factor with HDL levels (p=0.044). It can be concluded that there is no relationship between stress factors, carbohydrate, protein and fat intake with total cholesterol levels. There is no relationship between carbohydrate, protein and fat intake with HDL levels. There is a significant relationship between stress factors and HDL levels in overweight female students.
Differences in Prostaglandin f2α Level in Adolescent Girls Experienced and Not Experienced Premenstrual Syndrome: A Cross-Sectional Study
Authors: Ruqaiyah Ruqaiyah , Wulandari Ikrawanti Ayu , Harun Ayatullah , Irwan Hadriani , Amir Fatmawati , Alamsyah Alamsyah
Published: January 2024

This study aims to determine the differences in Prostaglandin f2α concentration in female adolescents who experienced and did not experience Pre-Menstrual Syndrome (PMS). Cross-sectional study conducted at a single institution. The sample for this study was female adolescents at the Darul Arqam Islamic Boarding School in Makassar, consisting of 50 adolescents who experienced PMS and those who did not experience PMS in a ratio of 1:1. Prostaglandin f2α levels were measured using an ELISA kit. The sample used was 5 cc blood from the median cubital vein by laboratory staff 5 days before menstruation. Data were analyzed descriptively and statistically. The results showed that the average Prostaglandin f2α in the group that experienced PMS (379.07) was higher compared to the group that did not experience PMS (101.23) with a p-value < 0.05, significantly. Furthermore, the group that experienced mild PMS had an average Prostaglandin f2α value of 283.32, while the group that experienced severe PMS had an average Prostaglandin f2α value of 454.31. The average Prostaglandin f2α level in the group who did not experience PMS, mild PMS, and severe PMS had a p-value < 0.05. This study concludes that there is a significant difference in the Prostaglandin f2α Level in adolescents who experience PMS and those who do not experience it and there are differences based on the severity of PMS.
Risk Factor Analysis of the Incidence of Hepatitis A in Indonesia: A Meta-Analysis
Authors: Cahyono Yoyon Hariadi , Azizah R. , Martini Santi , Sulistyorini Lilis
Published: January 2024

Hepatitis transmission is still a global public health issue, including in Indonesia. Low personal hygiene and environmental sanitation are the contributing factors to hepatitis A. This study aimed to analyze the impact of hand-washing habits, cutlery exchange, food and snack hygiene, and latrine use on the incidence of Hepatitis A. The study used meta-analysis with the PICOS technique. The data from Google Scholar, Mendeley, and Research Gate by looking at keywords such as “risk factors” and “hepatitis A”, which were then sorted according to the inclusion-exclusion criteria and obtained 16 full-text case-control articles. Data analysis used a fixed effect model through JASP software version 0.9.2. The meta-analysis found that hand-washing behavior had a risk of 1.131; food and snack hygiene had a risk of 6.233; the habit of exchanging cutlery had a risk of 10.17; and latrine utilization had the highest risk of 12.935 for the incidence of hepatitis A. The study found that the use of latrines is the most significant factor in the occurrence of hepatitis A due to open defecation. Furthermore, exchanging cutleries is rated as the second factor triggering hepatitis A transmission, followed by the consumption of snacks or other foods. The study also found that hand-washing behavior has the lowest risk of hepatitis A incidence. The study concludes that hand-washing behavior, latrine utilization, food and snack hygiene, and exchanges of cutlery increase the risk of hepatitis A at different levels. It is suggested that behavioral factors such as hand washing, the use of closed latrines, and the consumption of healthy snacks or foods are essential measures to educate the community about hepatitis A and reduce its transmission within the population.
Determining the Role of Exclusive Breastfeeding and Nutritional Status in Stunting Prevention: A Literature Review
Authors: Erwani Erwani , Susanti Dewi , Doni Alsri Windra , Yuda Rahmi Andrita , Yanti Meyi
Published: January 2024

Stunting among children is a serious global concern including Indonesia since it has a negative impact on children's growth and development. Globally, more than 148 million children are affected by stunting. In Indonesia, the prevalence of stunting was 21.6% in 2022, which reflected a serious problem that needs to be addressed. This study aims to explore the correlation between exclusive breastfeeding, nutritional status and stunting among under-five children in Indonesia. The current study explored the correlation between exclusive breastfeeding (EBF) and nutritional status with the incidence of stunting among under-five. The inclusion criteria consisted of original articles, open access, written in English/Indonesian, 2020-2023, discussed EBF, nutritional status, and stunting. Databases involved ScienceDirect, PubMed, BMC journals, Google Scholar. Article selection used keywords and MeSH, and the results were presented in a PRISMA diagram. It was conducted an analysis of 10 articles, which were grouped in a matrix based on author, year, journal name, title, methods, and results. The results revealed that exclusive breastfeeding practice was correlated with a 3.1-fold reduction in the risk of stunting (CI 95%=1.5–6.4). Factors such as good nutrition and breastfeeding for at least 6 months provided protection from the risk of stunting. In conclusion, exclusive breastfeeding and good nutritional status were required, along with strengthening education and promotion regarding nutritional fulfilment patterns. Integration of the study findings should be made in child health guidelines, which may further guide policy and practice, support concrete steps to reduce the prevalence of stunting, and ensure optimal growth of children. Recommendations in this study include improvement in maternal education, nutritional support, and child health policy advocacy. For next steps, in-depth research is needed to evaluate the impact of specific nutritional interventions, understand the social and cultural factors that influence nutritional practices, and assess the effectiveness of cross-sector programs in reducing the prevalence of stunting.
Telehealth Usage During The Coronavirus Disease 2019 Pandemic: A Meta-Analysis
Authors: Akbar Prima Soultoni , Putri Santy Irene , Widiyanto Aris , Atmojo Joko Tri , Prisusanti Retno Dewi , Ramadhanti Tarisa Aulia
Published: January 2024

The recent pandemic has increased telemedicine use tremendously, but it has also pronounced access gaps to telemedicine. This study aimed to investigate factors affecting patient use of telehealth during the Coronavirus Disease 2019 Pandemic. This article was created using a systematic review and meta-analysis study that searched for articles in electronic databases such as Science Direct, PubMed, and Google Scholar. Observational studies are included in full papers with a publication year until 2022 were searched for this study. The Review Manager 5.3 (RevMan) software was used to analyze the articles in this study. We observed heterogeneity with a random-effect model to analyze the effect size from each primary study, and the results were reported as an adjusted odds ratio (aOR) and corresponding 95 percent confidence interval (CI). A total of 9 articles reviewed in the meta-analysis (consisting of 4 articles in each variable) showed that patients whose primary language is non-English (aOR= 0.72; 95% CI= 0.59 to 0.87; p= 0.0008) and have Medicaid insurance English (aOR= 0.86; 95% CI= 0.77 to 0.97; p= 0.02) were less likely to use telemedicine compared to patients who speak English and utilize private insurance. Medication insurance and non-English as a preferred language reduced the likelihood of patients using telemedicine.
Profile of Cytostatic Drug Use in Breast Cancer Patients (Mammae carcinoma) at Medan Hospital
Authors: Sitepu Nadroh , Pasaribu Romaito , Hastuty Yulina Dwi
Published: January 2024

Breast cancer is the most common type of cancer in the world (2,261,419 cases) and in Indonesia (65,858 cases). This research aims to determine the class and type of cytostatic drugs most frequently used in breast cancer chemotherapy patients from January to March 2023 at RSUP Haji Adam Malik Medan. This study used a descriptive survey method with a saturated sample of 176 medical records. Data collection was done retrospectively by gathering information from the electronic medical records of the patients. The research results show that the characteristics of the patients are as follows: the majority were female, totalling 176 patients (100%). The most common age group was 45-54 years, with 111 patients (63.1%), and the prescription of cytostatic drugs was highest in March, with 80 patients (36.9%). In conclusion, the most commonly used class of cytostatic drugs was antibiotics, with 146 cases (32.88%), and the most commonly used type of cytostatic drug was Doxorubicin, with 114 cases (25.68%). This indicates that the use of antibiotics is a significant part of breast cancer treatment, and it is important to pay attention to the safety and regularity of drug use to prevent drug resistance and the severity of the disease.
Sungkai Leaf Extract (Peronema canescens Jack) Reduces MDA Levels and Increases IL-10 Levels in MSG-Induced Wistar Rats
Authors: Wahyudi Wahyudi , Chodijah Chodijah , Sumarawati Titiek , Afrianti Dina
Published: January 2024

The addition of Monosodium Glutamate (MSG) to ready-to-eat food can change eating habits, coupled with a lack of activity which can have an impact on health. MSG as a trigger for increased reactive oxygen species (ROS), causing systemic damage, the impact of excessive MSG consumption can be reduced by modifying the diet to contain high sources of antioxidants. Sungkai leaf extract can be an alternative as a natural antioxidant. Sungkai leaf extract antioxidants are expected to neutralize ROS thereby repairing cell damage. Objective: This study aims to determine how giving sungkai leaf extract affects MDA and IL-10 levels in MSG-induced mice. Method: Experimental research with a Randomized Post test only control group design. The total sample was 24 male Wistar rats divided into 4 groups. KN healthy mice, K(-) were given 1g MSG/rat, P1 was given 1g MSG/rat and 28mg sungkai leaf extract/rat, P2 was given 1g MSG/rat and 56mg sungkai leaf extract/rat. Results: The average results showed a decrease in MDA levels and an increase in IL-10 levels after treatment for 21 days, the One way Anova test followed by Post hoc LSD showed that each treatment group was significantly different from the control group where the MDA level in group P2 was 0, 07mg/ml ± 0.01 experienced a significant decrease compared to the KN group 0.07mg/ml ± 0.01 while IL-10 levels experienced a significant increase in the P1 group 130.10pg/ml ± 13.29 when compared to the KN group 60.43pg/ml ±17.40. Conclusion: Sungkai leaf extract (Penonema Canescens Jack) was able to reduce MDA levels at a dose of 56 mg/mouse in mice injected with 1gr MSG/rat and experienced a significant increase in IL-10 levels with a dose of 28 mg sungkai leaf extract/rat injected with 1gr MSG/rat.
The Relationship of Social Support with The Level of Independence for People with Mental Disorders (ODGJ) in Menur Mental Hospital (RSJ) Surabaya
Authors: Widiyawati Wiwik
Published: January 2024

Mental health is one of the things that is currently becoming an international issue discussed in the SDGs (Sustainable Development Goals). The healing process for ODGJ is carried out by carrying out mental rehabilitation. The intense support that people with mental disorders receive from outside themselves sometimes goes unnoticed, whether it comes from family, friends or health workers. The aimed to study and analyse the relationship between support from family, friends, and health workers on the level of independence in ODGJ. This research is a type of observational analytical research with a cross-sectional approach. Data collection was carried out using a questionnaire. The data in this study were analysed univariately using frequency distribution tables and bivariate using cross tables and the chi-square statistical test with significance α=0.05 using SPSS. The research results show that there is a relationship between support and the level of independence of ODGJ (p= 0.012), there is a relationship between friend support and the level of independence of ODGJ (p= 0.027), and there is a relationship between support from health workers and the level of independence for ODGJ (p= 0.001).
Worm Infections (Soil-Transmitted Helminthiasis) in Elementary School Students
Authors: Nur Nur Hamdani , Kartini Kartini , Arda Zul Adhayani
Published: January 2024

Environmental sanitation factors and human behavior factors are factors that greatly influence the occurrence of worm disease. The high incidence of worms is caused by environmental factors or demographic conditions in an area and is also influenced by community behavior. This study aims to determine the factors associated with the incidence of worms in elementary school students in Manggala District, Makassar City. This type of research is observational analytic with a cross-sectional study design. The population in this study were elementary school children in grades IV, V, and VI who attended SD Komplek Inpres, SD Perumnas Antang II, Manggala District, Makassar City, with a total sample of 61 samples. Sampling used the Systematic Random Sampling technique. This research found that 29.5% of elementary school students were positively infected, where Ascaris lumbricoides and Tricuris trichiura were the main infections. The results of the analysis showed that hand washing behavior (p=0.003), nail cleanliness (p=0.031), and clean water facilities (p=0.001) were significantly related to the incidence of worm infections in elementary school students, and the variable clean water facilities were the variable that most dominant in the incidence of worms in elementary school students.
The Effect of Ethanol Ants Nest Extract on Profil Lipid Mice Model Obesity with Type 2 Diabetes
Authors: Nuriza Rizky Alfiqi , Rahardjo Setyo Sri , Wijayanti Lilik
Published: January 2024

The Ants Nest plant (Myrmecodia pendans) is known to have the potential to reduce blood glucose cholesterol, LDL (Low-Density Lipoprotein), and HDL (High-Density Lipoprotein) in obese patients with Type 2 Diabetes (T2D) because it contains high flavonoid and tannin content that can prevent oxidative stress and inhibit the work of pancreatic β cells, α-glucosidase work, Glut-2, and lipase enzymes. This study aims to study the effect of the management of Ethanol Ants Nest Extract (EANE) on changes in the cholesterol, LDL, and HDL levels of obese rats with T2D. The extraction of the ants nest was carried out using the maceration method with ethanol solvent. Cholesterol, LDL, and HDL values will be obtained through the CHOD PAP. The rats were divided into 6 groups, namely: KNo (standard control), KN (T2D obesity), KP (T2D obesity given metformin), P1, P2, and P3 (T2D obesity given ethanol extract of ant nest 150mg/KgBW/day, 300mg/KgBW/day, and 600mg/KgBW/day for 14 days by gastric sonde). Induction of DM model using streptozocin and nicotinamide. Data were analyzed using Paired T-test and continued by using One-way ANOVA. There was a decrease in cholesterol, LDL, and HDL after 14 days of intervention, which was highest in the P3 group with cholesterol, LDL, and HDL of 64,06 ± 1,97 mg/dl (p < 0.0001), 44,56 ± 2,22 mg/dl (p < 0.0001), and 45,33 ± 2,56 mg/dl (p < 0.0001). The treatment of ethanol extract from ants nest has an effect in reducing cholesterol, LDL, and HDL.
Study of Anemia, Hemoglobin Level, and Subjective Well-being among Women of Reproductive Age in Indonesia
Authors: Suwarni Linda
Published: January 2024

Anemia is a burden for women of reproductive age (15 – 49 years old) which in Indonesia takes 22.3% of prevalence based on Basic Health Survey data in 2018. Women of reproductive health have different points of view according to their subjective well-being. This study aimed to examine the correlation between anemia status and hemoglobin level related to subjective well-being among women of reproductive age. This cross-sectional study used the Indonesia Family Life Survey (IFLS) wave 5 in 2014/15 with a total study sample were 12,818.  Subjective well-being is self-reported data with categories satisfied, somewhat satisfied, and not satisfied. Hemoglobin level is measured by blood test and if the Hb level is less than 12, it will be categorized as anemia. This study tested the analysis of univariate, bivariate (Chi-square and ANOVA), and multivariate (multinomial logistic regression) using STATA version 17.  The findings revealed that anemia and hemoglobin levels did not have a correlation with subjective well-being. However, some other covariates were found significantly associated with having satisfied subjective well-being including being married, pregnant, having poor SES, more than adequate of family life satisfaction, and adequate and more than adequate standard of life, with RRR 1.21, 1.21,0.63, 1.77, 1.19, and 1.74, respectively. It is concluded that subjective well-being is associated with not only health aspects but also social and economic. Intervention in the level of community is needed to improve the quality of life to achieve satisfied well-being. For example by joining the social group at the village level. Future study can include other health-based predictors at individual level that potentially predict subjective well-being.
Implementation of Accelerated Stunting Reduction at the Biromaru Public Health Center, Sigi Regency
Authors: Sudirman Sudirman , Rosnawati Rosnawati , Afni Nur , Yani Ahmad , Syukran Muhammad
Published: January 2024

This study aims to determine the implementation of stunting reduction policies at the Biromaru Public Health Center, Sigi Regency, a conceptual model using Edward III's theory from the aspects of Communication, Resources, Disposition, and Organizational Structure. The research method used is qualitative research, namely observation, in-depth interviews, and documentation. Based on the study results, it can be concluded that the stunting reduction policy implementation at the Biromaru Public Health Center in Sigi Regency has not run optimally. This is evident from the inadequate implementation of the aspects of Communication, Resources, Disposition, and Organizational Structure. Several obstacles hinder the implementation of stunting reduction policies. The resources at the Biromaru Health Center in Sigi Regency are lacking, especially in terms of facilities like scales and height measuring devices. Not all posyandu centers receive these resources due to budget limitations, which vary by village. This affects the optimal implementation of the policy. Regarding the Organizational Structure and Standard Operating Procedure (SOP), while they have not yet been established, all officers maintain a good working relationship, as confirmed through interviews showing their collaborative efforts in the program.
Predictor of Postpartum Depression: Literature Review
Authors: Lestari Indah , Saudah Noer , Rofi’ah Ika Ainur , Nugroho Heru Santoso Wahito
Published: January 2024

The incidence of postpartum depression is quite high. The largest percentage occurs when they have their first child, and have a family history of mood disorders. The incidence of postpartum depression is 50 - 60% in mothers when they have their first child, and around 20% in mothers who give birth to subsequent children. This study aims at reviewing and synthesizing the determinants factor of depression among adolescent in rural area. This study design was a systematic review using the PICO framework. This data was carried out from various journal databases 2012-2022, including Scopus, ScienceDirect, PubMed. 16 articles meet the inclusion criteria and meet the qualifications for review. A systematic procedure is used to collect articles, as well as a critical appraisal and data synthesis with qualitative synthesis. The analysis of the literature review found that aspects of findings related to predictors of postpartum depression are as follows: socio-demographic factors (age, socio-economic status, education, risk age group), maternal factors (pregnancy spacing, parity, pregnancy condition, birth experience, postpartum complications), biological factors (hypothalamus function, prolactin, CRH, inflammatory process), psychosocial factors (negative mood, anxiety, unpreparedness, history of depression), cultural factors (children care stress, wisdom), support system (support husband, family support, decision-making patterns). Healthcare professionals should be aware of this phenomenon and strategies such as primary, secondary, and tertiary prevention interventions may be applied. Women should be screened for potential risk factors and depressive symptoms during pregnancy and postpartum periods so that appropriate interventions if needed, can be initiated in a timely fashion.
Effectiveness of the Sensitive Nutrition Intervention Program in Accelerating Stunting Reduction in Baubau City
Authors: Andriani Rininta , Islamy La Ode Syaiful
Published: January 2024

Stunting is a condition of failure to thrive in toddlers due to long-term malnutrition, exposure to repeated infections, and lack of stimulation. Not all short toddlers are stunted, so pediatricians need to differentiate them, but stunted children are scarce. Responding to this problem, the government issued Presidential Regulation (Perpres) Number 72 of 2021 concerning the Acceleration of Reducing Stunting. This regulation is a form of the government's commitment to accelerating the achievement of the stunting reduction target to 14 percent by 2024. This research aims to describe the effectiveness of a sensitive nutrition intervention program to accelerate stunting reduction in Baubau City, focusing on the accuracy of program targets and program outreach. The research used a qualitative design with a phenomenological approach. Data was collected through in-depth interviews with six informants, while secondary data came from related regional government organization (OPD) data. The data was then analyzed in several stages: data collection, reduction, presentation, and conclusion drawing. The research results show that based on indicators of the accuracy of program targets and program outreach in sensitive nutrition intervention programs, the acceleration of stunting reduction in Baubau City has been running effectively even though it has not significantly contributed to reducing the stunting prevalence rate. The decline in the stunting prevalence rate of only 1% shows that the accuracy of program targets still needs to be improved. Access to drinking water and sanitation, community recipients of PKH benefits, and the formation of farming community groups in the future must be several things that need to be maximized to achieve an accelerated reduction in stunting in Baubau City. In conclusion, the consistency of policy implementers must be bound by a shared commitment and shared goals and understanding in efforts to reduce the prevalence of stunting.
Antioxidant Activity and Amino Acid Profile of "Dadih" from Various Regions in West Sumatra, Indonesia
Authors: Habibi Nur Ahmad , Gusnedi Gusnedi , Sartika Wiwi , Ismanilda Ismanilda
Published: January 2024

Dadih or curd is a traditional product typical of West Sumatra which is made through natural fermentation using the lactobacillus plantarum bacteria in bamboo. Each region in West Sumatra makes curd in various ways that affect its quality. This study aims to determine the amino acid profile and antioxidant activity of curd from various regions in West Sumatra. The study was conducted by testing curd from 4 main curd center regions, namely Bukittinggi, Payakumbuh, Batusangkar and Alahan Panjang. Certain tests were applied to assess the protein content using the Kjedahl method, amino acids content using the HPLC method and antioxidant activity using the DPPH method. The test results showed that curd from Payakumbuh had a higher protein and amino acid content compared to other regions. Furthermore, such curd had the highest level of antioxidant activity towards free radicals compared to other regions, with an IC50 value of 95.11 ± 0.40 mg/kg, which was included in the strong category. There was a significant relationship between amino acid content and antioxidant activity of curd. It can be concluded that curd from Payakumbuh had the best amino acid content and antioxidant activity compared to other regions in West Sumatra.
Quality and Pattern of Breakfast Through the GEMPITA PROGRAM at Palu City, Central Sulawesi
Authors: Ariany Darma , Adhyanti Adhyanti , Eka Cahyani Yayuk , Hafid Fahmi , Wahyuni Rosa Dwi , Ngatimin Dachruddin
Published: January 2024

Many school-aged children in Indonesia still skip breakfast, which can have an impact on their learning concentration and academic performance at school. This study aims to describe the quality and pattern of breakfast through the GEMPITA Program at Palu City, Central Sulawesi. This was a descriptive study with a sample size of 228 elementary and junior high school students in Palu City. Data collection was performed through interviews using structured questionnaires and anthropometric measurements. The study results show that the majority of respondents had pocket money of more than IDR 5,000/day, came from families with fathers of senior high school graduates and non-civil servants, the mothers generally had primary and secondary education and were housewives. Furthermore, the majority of respondents had a routine breakfast habit by 57.9%, 20.2% had breakfast sometimes and 21.9% never had breakfast. Furthermore, only 32.9% had quality breakfast menu. Regarding snack consumption habit, the majority of respondents by 77.2% consumed snacks more than three times a week and more than half of respondents by 58.3% had the habit of bringing packed meal, while 41.7% never brought packed meal. An assessment of the nutritional status of respondents showed that there were still 33.3% who were undernourished and 7.9% who were over nourished and obese. Stunting status occurred in 18.9% of respondents. The breakfast habit, quality and pattern of elementary and high school students still need to be improved. The GEMPITA program is an alternative program to improve the pattern and quality of breakfast for elementary and high school-aged children in Palu City.
Pemanfaatan Tanaman Obat Keluarga sebagai Upaya Meningkatkan Imunitas di Masa Pandemi Covid 19
Authors: Aminuddin Aminuddin , Supetran I Wayan , Nurmalisa Baiq Emy
Published: January 2024

Pendahuluan Selama masa pandemi, banyak individu yang berupaya menjaga kesehatan dan keselamatan pribadi mereka untuk menghindari paparan virus Covid-19. Upaya ini mencakup peningkatan imunitas atau daya tahan tubuh guna melindungi diri dari berbagai jenis serangan patogen, sehingga tubuh dapat tetap dalam keadaan yang sehat. Salah satu langkah untuk mencegah penularan Covid-19 adalah menggunakan metode kesehatan tradisional, yang melibatkan pelaksanaan perawatan kesehatan mandiri dengan memanfaatkan Tanaman Obat Keluarga (TOGA). Tujuan pengabdian masyarakat ini adalah meningkatkan pengetahuan masyarakat terkait pemanfaatan tanaman obat keluarga dalam upaya menjaga kesehatan dan imunitas serta membuat kebun percontohan toga di Puskemas Wani.  Metode Kegiatan pengabmas berupa sosialisasi dilaksanakan pada tanggal 23 September 2020 dengan peserta sebanyak 20 ibu kader dan pembuatan kebun percontohan TOGA. Hasil penyuluhan yang diberikan terbukti dapat meningkatkan pengetahuan peserta terkait pemanfaatan TOGA untuk kesehatan. Di sesi evaluasi peserta mampu menjelaskan definisi Tanaman Obat Keluarga (TOGA), keuntungan menanam TOGA di pekarangan rumah, jenis-jenis TOGA yang dapat ditanam di pekarangan rumah, dan manfaat TOGA untuk mengatasi berbagai penyakit terutama untuk meningkatkan imunitas serta cara pengolahannya. Keberhasilan pengabdian ini juga terlihat dari hadirnya kebun TOGA percontohan yang terdapat di halaman belakang Puskesmas Wani. Saran diharapkkan Puskesmas Wani untuk terus menggalakkan sosialisasi terkait pemanfaatan TOGA.
Hubungan Status Pekerjaan Ibu dengan Perkembangan Anak Toddler di Wilayah Kerja Puskesmas Talise
Authors: Farhana Ririn , Lenny Lenny , Patompo Fadli Dg. , Nurmalisa Baiq Emy
Published: January 2024

Pertumbuhan dan perkembangan mengalami peningkatan yang pesat saat anak berusia 0-5 tahun yang biasa disebut sebagai  fase “Golden Age”.  Peran ibu diperlukan dalam memenuhi kebutuhan dasar untuk tumbuh kembang anaknya, mengingat hubungan keeratan emosional antara ibu dan anak sangat dekat. Tujuan penelitian ini adalah diketahuinya hubungan  antara status pekerjaan ibu dengan perkembangan anak toddler di Wilayah Kerja Puskesmas Talise.

Penelitian ini merupakan metode penelitian analitik observasional  dengan pendekatan cross sectional. Sampel  penelitian berjumlah 43 anak toddler dengan umur 12-14 bulan dengan teknik pengambilan sampel yaitu  purposive sampling. Data dikumpulkan dengan menggunakan kuesioner  dan Formulir Kuesioner Pra Skrining Perkembangan (KPSP). Analisis bivariat dengan uji Chi-Square.

Hasil  penelitian menunjukkan mayoritas anak adalah dengan perkembangan sesuai dengan tahap perkembangannya sebanyak 32 anak (74,4%) dan mayoritas ibu dari responden tidak bekerja yaitu sebanyak 23 orang (53,5%). Hasil uji  chi-square diperoleh p value yaitu 0,257 (p > 0,05) artinya tidak ada hubungan yang signifikan antara status pekerjaan ibu dengan perkembangan pada anak toddler di Wilayah Kerja Puskesmas Talise. Saran penelitian ini Puskesmas Talise agar meningkatkan pelayanan kesehatan anak tentang perkembangan anak terutama dalam pengembangan program SDIDTK (Stimulasi, Deteksi dan Intervensi Dini Tumbuh Kembang Anak).
Pengalaman Orang Tua Mahasiswa pada Program Vaksinasi Pencegahan Covid-19
Authors: Suswinarto Dwi Yogyo , Evie Sova
Published: January 2024

Pandemi Covid-19 telah menyerang seluruh belahan dunia termasuk Indonesia, menjadipenyebab morbiditas dan mortalitas yang tinggi. total kasus Covid-19 di Indonesia mencapai 4.257.685dan Jumlah kasus meninggal 143.867orang, Upaya Pemerintah dalam mengendalikan Pandemi Covid-19dengan mengeluarkan, Peraturan Pemerintah no. 20 Tahun 2020 tentang pembatasan sosial berskalabesar. Kegiatan pencegahan yang dilaksanakan pada tingkatan individu dan dimasyarakat yakni Mencucitangan, memakai masker, menjaga Jarak, menjauhi kerumunan dan membatasi untuk keluar rumah (5M), dan tindakan 3T Pemerintah juga melakukan upaya Pemberian vaksinasi. Sudah Hampir 1 tahun sejakprogram vaksinasi covid-19 di gulirkan percepatan pencapaian vaksinasi masih sangat rendah. Tujuan penelitian menggali Pengalaman dalam mengikuti program Vaksinasi Covid-19’ Penelitian inimenggunakan desain penelitian kualitatif dengan pendekatan interpretive, partisipan dalam penelitian iniadalah orang tua mahasiswa Program studi D3 Keperawatan Tolitoli yang bersedia menjadi partisipan,alasan orang tua Mahasiswa sebagai partisipan adalah bahwa mahasiswa saat ini berada di kampungmasing-masing, belajar secara onlie. Dengan menggunakan tehnik purposive sampling. Jumlah partisipanyang bersedia dan mengisi pertanyaan sebanyak 122 partisipan. Pengambilan data menggunakanpertanyaan terbuka diberikan melalui google formulir sebanyak 13 pertanyaan. Analisis dengan metodecolaizzi,dimana data-data dimasukkan dalam beberapa kategori, beberapa sub tema dan tema.Kemudian disimpulkan. Pengambilan data di laksanakan pada bulan Desember 2021 s.d Januari 2022Hasil penelitian ditemukan 4 tema yaitu : 1). Penyakit Covid-19, 2). Vaksinasi, 3). Pengalaman Partisipanyang telah di Mengikuti program vaksinasi 4) Pengalaman Partisipan yang tidak mengikuti vaksinasi.
In-silico design of a new multi-epitope vaccine candidate against SARS-CoV-2
Authors: Alibakhshi Abbas , Alagheband Bahrami Armina , Mohammadi Elmira , Ahangarzadeh Shahrzad , Mobasheri Meysam
Published: January 2024

Frequent, and sometimes more dangerous, mutations in SARS-CoV-2 indicate that a stronger strategy is needed to produce an effective vaccine—a vaccine that contains a wider range of virus factors and remains effective if one or more mutations have occurred in a part of the genome. In this study, four important virus proteins were used to make a multi-epitope protein vaccine. For this purpose, antigenic determinant of 4 proteins were selected and a protein structure was designed using 4 domains containing epitopes. After examining its antigenic potential, its three-dimensional structure was designed and then docked with immune system receptors. Finally, using the dynamic molecular (MD) simulation, complexes and interactions were investigated and their interaction energies were measured. The results of the study showed that the designed structure has good relative stability and interacts well with its receptors and can be used as a vaccine candidate for further studies.
Technology in anesthesiology: friend or foe?
Authors: Saasouh Wael , Suchocki Ewelina , Weeks Matthew , McKelvey George , Jaffar Muhammad
Published: January 2024

The field of medical technology has undergone significant advancements over the years, from the use of ancient scalpels, forceps, and sutures to complex devices like intraoperative MRI suites, artificial intelligence-enabled monitors, and robotic surgical systems. These advancements have had a profound impact on the way we diagnose, treat, and prevent diseases, and have significantly improved the quality of life for millions of people around the world. As we move forward, it is important to reflect on the direction of medical technology and consider the potential risks and benefits of new advancements. We must also ensure that these technologies are accessible to all and that they are used ethically and responsibly. There is still much to be discovered and developed in the field of medical technology, and it is up to us to ensure that we are moving in a positive direction that benefits everyone.
Novel quality feed from a wasted resource: measuring the nutritional value of low-glycoalkaloids potato haulm in sheep
Authors: Kilama Justine , Izhiman Batool , Wagali Philip , Sabastian Chris , Ngomuo Godliver , Rabinowitch Haim , Mabjeesh Sameer J.
Published: January 2024

This study evaluated the potential of low-glycoalkaloid potato haulm (LGPH) as a high-quality feed for ruminants. The low-glycoalkaloid potato plants were grown in a net house following standard agricultural practices. Dehaulming was performed a fortnight before the harvest of the tubers, as commercially practiced. Four healthy female lambs (aged 4 months) were employed in a 4×4 Latin square feeding experiment design. The lambs were fed with either a maintenance diet consisting of 73% roughage (control), or treatment diets with supplementation of 10% (P10), 15% (P15), and 20% (P20) LGPH on a dry matter (DM) basis for a period of 21 days, including 14 days of adaption and 7 days of sampling. Refusals and feces were collected for 6 days and pooled followed by a 24 h urine collection on the 7th day. On the 6th day, an hour after morning feeding, blood, and rumen liquid samples were collected. All the samples were analysed, and the data generated were analysed using ANOVA with diet and period as fixed effects and sheep as a random effect. Orthogonal contrasts were used to detect linear and quadratic effects of LGPH in the diet. Linear or polynomial equations were produced to extract the nutrient digestibility and metabolizable energy (ME) of LGPH. No toxicological clinical signs were observed, and the haematology profiles were normal throughout the trial. LGPH did not affect the daily intake of nutrients and energy. However, the apparent digestibility of DM, organic matter (OM), crude protein (CP), and gross energy increased (P= 0.01) linearly (P< 0.01) with supplementation of LGPH in the diet. The inclusion of LGPH had a quadratic effect on neutral detergent fiber (NDF) digestibility (P= 0.027), reaching a peak of 54.8 % at 12.3 % LGPH supplement on a DM basis. The N retention in lambs fed with the P20 diet was nearly twice that of the control diet (P= 0.032; 19.1 vs. 10.2 g/d). The computed digestibility values of DM, OM, CP, and NDF for LGPH were 76.1, 79.7, 84.2, and 72.1 %, respectively, and ME was 2.62 Mcal/kg DM. Conclusively, by significantly reducing the glycoalkaloids’ content in potato haulm, we can safely repurpose the currently wasted foliage as a new source of high-quality roughage feed for ruminants, equivalent to alfalfa hay, without imposing any additional environmental burden. However, further research is necessary to assess impact of LGPH on growth performance, and milk productivity before practical application on commercial farms.
Bridging the gap between academic and industry Li-ion battery research
Authors: Ha Yeyoung , Licht Rachel B. , Bogart Timothy D. , Beers Keith M.
Published: January 2024

The field of lithium (Li)-ion batteries has entered a stage where industry is largely focusing on optimizing current cell chemistries to increase the effective energy density of commercial cells while academia is mainly driven by the development of novel materials for next-generation cell chemistries. In addition to their different research goals, industry is producing commercial cells with increasingly diversified size and shape, while the majority of academic research reports on limited small sized cell formats. Such differences in research settings are leading to a disconnect between industrial and academic perspectives. More specifically, a disconnect arises due to academic research results obtained from smaller scale cells not translating to cells with more complex designs. In this paper, we discuss where a disconnect between industry and academia exists, and demonstrate how industry relevant problems can be studied in academia by utilizing a multifaceted approach and further provide valuable insights at a practical level.
Mendelian randomization analysis to investigate the gut microbiome in oral and oropharyngeal cancer
Authors: Zhang Qihe , Wang Huanhuan , Tian Yuan , Li Jinjie , Xin Ying , Jiang Xin
Published: January 2024

Background

Evidence supports an observational association between the gut microbiome and susceptibility to extraintestinal cancers, but the causal relationship of this association remains unclear.

Methods

To identify the specific causal gut microbiota of oral and oropharyngeal cancer, we performed two-sample Mendelian randomization (MR) analysis of gut microbiota on oral and oropharyngeal cancer using a fixed-effects inverse-variance-weighted model. Gut microbiota across five different taxonomical levels from the MiBioGen genome-wide association study (GWAS) were used as exposures. Oral cancer, oropharyngeal cancer and a combination of the two cancers defined from three separate data sources were used as the outcomes. Odds ratios (ORs) and 95% confidence intervals (CIs) for disease per standard deviation (SD) higher abundance of microbiome.

Results & Conclusions

There was little evidence for a causal effect of gut microbiota on oral and oropharyngeal cancer when using a genome-wide p-value threshold for selecting instruments. Secondary analyses using a more lenient p-value threshold indicated that there were 90 causal relationships between 58 different microbial features but that sensitivity analyses suggested that these were possibly affected by violations of MR assumptions and were not consistent across MR methodologies or data sources and therefore are also to unlikely reflect causation. These findings provide new insights into gut microbiota-mediated oral and oropharyngeal cancers and warrant further investigation.