bluuebunny/crossref_metadata_2025 huggingface dataset:
DIGITAL ENGINES AT WORK: PROMOTING RESEARCH SKILLS IN STUDENTS
Authors:   Institute of Foreign Languages, Moscow City University, Russia, Suleimanova Olga , Fomina Marina ,   Institute of Foreign Languages, Moscow City University, Russia, Vodyanitskaya Albina ,   Institute of Foreign Languages, Moscow City University, Russia
Published: August 2021

The paper focuses on the digital teaching and research practices which make an indispensable integral component of upscale education. The authors compare traditional approaches to education against the much demanded by the society, promising approaches which heavily rely on the digital engines. Most relevant –education-wise –features of centennials / millennials, also referred to as “digital natives”, are taken into account. The digital teaching practices and digital research practices that can be used in teaching are outlined; teaching and research potential of some digital engines is examined. Corpus-based experiment along with the analysis of search engine results, cultural-linguistic research through Google and Yandex searching, Tropes Zoom’s content analysis and some other methodological novelties that can be used in the classroom as well as facilitate and substantiate the research results are analysed.
NATURE OF SCIENCE INTERDISCIPLINARY TEACHING AT PRIMARY SCHOOL BASED ON SYMMETRY AND THE SEARCH OF INVARIANTS
Authors:   Mathematics Division, School of Science and Technology, University of Camerino, Italy, Brasili Simone , Piergallini Riccardo ,   Mathematics Division, School of Science and Technology, University of Camerino, Italy
Published: August 2021

The project is situated in the field of teaching physics, generally speaking, science education. It aims at studying the interplay between physics and mathematics, introducing an interdisciplinary approach based on the modern concept of symmetry or sameness within change (i.e., invariance). The interdisciplinary methods integrate the process skills common to discovery-based science and problem-based mathematics, typically of Nature of Science (NoS) modelling. We designed a teaching-learning sequence(TLS) and implemented it in an Italian primary school on a sample group (N = 96). Research conforms to pre-and post-test design with a control group. The resulting data were examined through a mixed method. We assess the effectiveness of the TLS by analysing the learning changes in the level of pupils’ knowledge of symmetry. The findings show that the pupils were in the regime of competence for grasping the changed view of symmetry. It also provides ideas that the concepts of symmetry and invariance will allow building the architecture of more extensive scientific knowledge. The study of transformations and invariants facilitates the acquisition of cognitive procedures fitting in many domains, modelling and generalization processes. This research contribution brings important suggestions for designs of successive steps in the learning path on symmetry.
INTERDISCIPLINARY INNOVATION CAMP FOR NURSING AND ENGINEERING STUDENTS AT WNUAS
Authors:   Western Norway University of Applied Sciences, Norway, Husabø Eivind Standal , Kyrkjebø Dagrun ,   Western Norway University of Applied Sciences, Norway, Sande Joar ,   Western Norway University of Applied Sciences, Norway
Published: August 2021

Western Norway University of Applied Sciences(WNUAS)in cooperation with Junior Achievement Sogn og Fjordane, organizes interdisciplinary innovation camps for nursing and engineering students. The student assignments are given by local businesses and organizations. This study’s objective is to evaluate and develop new programs for innovation camps, as well as to share ideas with educators working with this type of learning activity. A qualitative method was used, and a focus group interview was conducted involving nursing and engineering students (n=8). The students were satisfied with innovation camp as a method for learning, and the learning outcome was good. They regard innovation camp as a diverging learning method. The students are lacking a common understanding of innovation and entrepreneurship before participating at the event, the assignments were too limited, and they were not challenging enough for creative thinking. This study leads to several conclusions to improve upcoming innovation camps at WNUAS. The improvements can be separated into two categories: 1. The students need to be better prepared for the event. 2. The assignments need to be more open.
TODAY’S HIGHER EDUCATION AT A CROSSROADS - The critical point and paradigm shift in the educator’s role
Authors:   Doctoral School of Entrepreneurship, Business Engineering & Management University “Politehnica” of Bucharest, Romania, Scarlat Cezar
Published: August 2021

Observing the different progress rates of the available data, information and knowledge (on one side) and human capacity to process these available data, information and knowledge (on the other side), the author becomes aware of the higher pace of the first –in the midst of impetus of new communication and information technologies –and argues that, at this point in time, we are eye-witnessing a real education paradigm shift. The education system is at a critical point in time (call it critical point in education –CPE) when the educator’s role must change from knowledge repository to skilled, expert knowledge explorer and identifier, switching from teaching the subject to teach students how to pick the right and relevant information related to the subject –from the ocean of available data. The current corona-crisis –which started by the time when the ideas for this chapter were put together –made this question more acute, asking for re-thinking the education system and educator’s role. This chapter launches the thesis of the education paradigm shift –in that respect of the educator’s role in the predictable future, to provoke a discussion, and to open a research path, for higher education strategists, policy makers, scholars and educators.
La biblioteca
Authors: Acuña Luisa Fernanda
Published: August 2021

Este artículo es una reseña sobre la obra: Método Invariante para la Enseñanza de la lectura'' Una, aproximación histórico cultural de los autores Yulia Solovieva y Luis Quintanar. se describen de manera detallada los fundamentos teóricos de la neuropsicología y la psicopedagogía, en los que se basan los autores para desarrollar el método. Se describe también el método invariante en sus diferentes etapas. La autoria incluyendo algunos comentarios acerca del proceso descrito para la enseñanza de la lectura haciendo énfasis de la importancia de conocer de manera profunda los procesos cognoscitivos del sujeto que aprende para desarrollar desde allí propuestas didácticas que faciliten el aprendizaje de procesos tan complejos como la lectura.
Conflicto escolar y formación ciudadana.Apuntes para una lectura agonística de la cotidianidad escolar
Authors: Pinilla Díaz Alexis
Published: August 2021

En el presente artículo se propone una reflexión sobre las características del conflicto escolar en algunas instituciones educativas de Bogotá y su relación con los procesos de formación ciudadana. El objetivo es mostrar que el conflicto no debe considerarse como algo anormal, disfuncional, en la vida escolar, sino, por el contrario, como un espacio de construcción de democracia y ciudadanía activas.
ASSESSMENT OF LIVING STANDARDS OF POPULATION OF STAVROPOL REGION
Authors:   Doctor of Economic Sciences, Professor of the Department of Finance, credit and insurance, Stavropol State Agrarian University, Stavropol, Russia, AGARKOVA L. V. , VOROBIEV N. N. ,   Doctor of Economics, Professor of the Department of Economics and Management, Don State Technical University, Technological Institute of Service (branch), Stavropol, Russia, PUCHKOVA E. M. ,   Candidate of Economic Sciences, Associate Professor of the Department of Economics and Management, Nevinnomyssk State Humanitarian and Technical Institute, Nevinnomyssk, Russia
Published: August 2021

The article is devoted to the problems of employment of the population related to the standard of living of the population. The authors call for improving the legislation in the field of the labor market, adopting new draft laws and motivating people to work to raise their well-being and ensure income stability.
PLANNING OF LOGISTICS SUPPORT FOR THE DISPOSAL OF HOUSEHOLD E-WASTE
Authors:   Graduate student, Entrepreneurship and Logistics Department, Plekhanov Russian University of Economics, Moscow, Russia, THI THU HUONG NGUYEN ,   lecturer University of Transport Technology, Hanoi, Vietnam, LARIN O. N. ,   Doctor of Economics, Professor of the Entrepreneurship and Logistics Department, Plekhanov Russian University of Economics, Moscow, Russia
Published: August 2021

The article describes the factors associated with the planning of logistics support for the disposal of household electronic waste. Identifying these factors plays an important role in coordinating to ensure the cost-effectiveness of the costs of recycling e-waste at all stages of the supply chain from the source of waste to where it is accumulated and then recycled. The article describes the importance of such processes as: the development of a method for determining the volume of household electronic waste generated in the administrative-territorial district, the creation of a network of waste collection points, the determination of the amount and throughput of waste collection points, the need to organize garbage collection from the place of collection at the lowest cost. The study was conducted on the basis of an analysis of official statistics from the five most populous cities in Vietnam and thirty regions of Hanoi.
ECONOMIC AND MATHEMATICAL MODEL OF MANAGING THE FINANCIAL RESOURCES OF COMMERCIAL BANK FROM OPENING AND MAINTAINING MEDICAL SAVINGS ACCOUNTS OF CITIZENS
Authors:   Doctor of Economics, Associate Professor, Sub-faculty of Finance of Engineering Business and Management faculty (EBM5), Bauman Moscow State Technical University, Moscow, Russia, KOSTYRIN E. V.
Published: August 2021

An economic and mathematical model of managing the financial resources of a commercial bank when opening and maintaining medical savings accounts of citizens was developed and implemented on the example of Sberbank PJSC in Moscow. The application of the model allows us to ensure the growth rate of PJSC's net profit from opening and maintaining medical savings accounts for the first year in the amount of 9,48%. Over the period of a person's labor activity (40 years), Sberbank's profit in this area will amount to 648 billion rubles, which is comparable to the bank's net profit for all its operations in 2020.
CROSS-FUNCTIONAL TECHNOLOGIES AND MODERN DIRECTIONS OF DEVELOPMENT OF THE INNOVATIVE ENVIRONMENT
Authors:   Chief Specialist of the Department of Organization and Conducting Inspection Control of Serial Material and Technological Services, LLC RN-Supply-Samara, CHERTOPYATOV D. A.
Published: August 2021

The article provides a definition of the concepts of “innovation” and “innovation environment”. The main directions of the development of the innovative environment in the region and at an individual enterprise are revealed. The characteristic of cross-functional interaction is given – the definition of the term is given, the main advantages of this technology are indicated. The influence of cross-functional interaction on the process of creating and developing an innovative environment is considered.
HUBUNGAN PANJANG TUNGKAI DENGAN KEMAMPUAN TENDANGAN SABIT PENCAK SILAT
Authors: Lamusu Ahmad , Lamusu Zulkifli
Published: August 2021

Penelitian ini bertujuan untuk mengetahui Hubungan antara panjang tungkai dengan kemampuan tendangan sabit pada mahasiswa Program Studi Pendidikan Jasmani Olahraga Kesehatan dan Rekreasi (PJKR) Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Metode penelitian yang digunakan adalah metode Penelitian kuantitatif yang bersifat korelasi. Adapun sampel dalam penelitian yang ditetapkan adalah sebanyak 24 mahasiswa Program Studi Pendidikan Jasmani Olahraga Kesehatan dan Rekreasi (PJKR) Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. yang diambil secara Purposive sampling. Hasilnya, terdapat hubungan yang signifikan antara panjang tungkai dengan kemampuan tendangan sabit pada mahasiswa Program Studi Pendidikan Jasmani Olahraga Kesehatan dan Rekreasi (PJKR) Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo.
Pelatihan Mengaktifkan Pembelajaran Daring dengan Memanfaatkan Aplikasi Mentimeter, Whatsapp dan Pembuatan Video Pembelajaran untuk Inovasi Mengajar dengan Keterbatasan Bandwidth Internet
Authors: Ni Wayan Wardani  , Andika I Gede
Published: August 2021

Pandemi Covid-19 telah membuat banyak perubahan di segala bidang termasuk Pendidikan. Pandemi telah memaksa para Guru untuk mengadakan kegiatan belajar mengajar secara. Banyak aplikasi yang dapat dimanfaatkan sebagai media belajar tetapi tidak semua aplikasi tersebut dapat dijalankan dengan baik di tengah keterbatasan bandwidth internet terutama di daerah pedesaan dan terpencil. Hal tersebut menuntut Guru untuk berinovasi dalam mengajar. Sebagai salah satu kampus IT di Bali, STMIK STIKOM Indonesia melihat fenomena tersebut dan ingin memiliki peran dalam memberikan pemahaman dan mengedukasi seluruh civitas akademika terkait inovasi dalam pembelajaran daring di tengah keterbatasan dengan memberikan pelatihan bagaimana memanfaatkan aplikasi Mentimeter, Whatsapp dan Pembuatan Video Pembelajaran. Dari jumlah peserta dan hasil kuisioner menunjukkan pelaksanaan kegiatan pengabdian ini mendapat respon positif dan antusias luar biasa dari para Guru selaku peserta.
Penyediaan Alat Peraga dan Pelatihan Pengajaran Sains dan Matematika Bagi MI Mambaul Hidayah Desa Sidorejo Kecamatan Jabung Kabupaten Malang
Authors: Emzain Zakki Fuadi
Published: August 2021

Alat peraga merupakan salah satu bentuk media ajar yang mempunyai peran penting dalam metode pembelajaran. Fasilitas pembelajaran di MI Mambaul Hidayah masih tergolong minim sehingga perlu adanya penyediaan alat peraga. Pengabdian pada masyarakat ini bertujuan untuk menyediakan dan melatih penggunaan alat peraga khususnya pada mata pelajaran sains dan matematika di MI Mambaul Hidayah Kabupaten Malang. Tahapan pengabdian meliputi survei, koordinasi, penyediaan, pelatihan dan simulasi pengajaran, serta evaluasi dan serah terima alat peraga. Hasil kegiatan pengabdian setelah simulasi pengajaran dengan menggunakan alat peraga sains dan matematika menunjukkan guru semakin mudah untuk menjelaskan materi dengan berbagai contoh yang aplikatif. Siswa juga semakin antusias praktik menggunakan alat peraga dan lebih mudah untuk mengerti dan memahami materi.
EXPERIENCE IN USING ULTRA HIGH
PERFORMANCE FIBER REINFORCED
CONCRETE ELEMENTS
Authors: MARCHENKO Maxim , CHILIN Igor , SELYUTIN Nikita
Published: August 2021

The article presents examples of the use of

ultra-high performance fiber reinforced concrete

for load-bearing structures in Russia.

Using this material with limits of compressive

strength 150 MPa, flexural tensile strength

21 MPa, tensile strength 8.5 MPa, external

post-tensioned structures of bridges and tanks

are made instead of common solution with the

steel anchors.

Full-scale tests of anchors were carried out,

which did not reveal signs of deformations and

destruction of elements during the tension of

strands, at the level of design and ultimate

loads - before strands rupture.

It was concluded that it is advisable to replace

steel anchors with anchors from the

material, which, with high strength characteristics,

has ultra-low permeability and high

frost resistance corresponding to the F21000 class. The estimated economic effect of such a replacement is determined by the reduced

cost of these elements of structures made

of ultra-high performance fiber reinforced

concrete in comparison with steel.
Sicherheit und Intelligenz auf Modulebene
Authors: Krause Wolfram
Published: August 2021

Die Installation von Photovoltaik (PV)-Anlagen wird für Hausbesitzerinnen und -besitzer wie auch für Unternehmen aufgrund ihrer verbesserten Wirtschaftlichkeit immer attraktiver. Bei der wachsenden Verbreitung von Solarenergie ist es wichtig zu bedenken, dass es sich um komplexe Mini-Kraftwerke handelt. Wolfram Krause, Director of Product Europe bei SolarEdge Technologies, erläutert was dabei zu bedenken ist und welche Möglichkeiten die „SafeDC“-Technologie hier bietet.
Dataset Suara dan Teks Berbahasa Indonesia Pada Rekaman Podcast dan Talk show
Authors: Novela Martin , T. Basaruddin
Published: August 2021

Salah satu faktor keberhasilan suatu model pembelajaran dalam machine learning atau deep learning adalah dataset yang digunakan. Pada tulisan ini menyajikan dataset suara dari rekaman podcast dan talk show beserta transkripsi berbahasa Indonesia. Dataset ini disajikan karena belum adanya ketersediaan dataset berbahasa Indonesia yang dapat diakses secara publik untuk digunakan pada pembelajaran model Text-to-Speech ataupun Audio Speech Recognition. Dataset terdiri dari 3270 rekaman yang diproses untuk mendapatkan transkripsi berupa teks atau kalimat berbahasa Indonesia. Dalam pembuatan dataset ini dilakukan beberapa tahapan seperti pra-pemrosesan, tahapan translasi, tahapan validasi pertama dan tahapan validasi kedua. Dataset dibuat dengan format yang mengikuti format dari dataset LJSpeech untuk memudahkan pemrosesan dataset ketika digunakan dalam suatu model sebagai input. Dataset ini diharapkan dapat membantu meningkatkan kualitas pembelajaran untuk pemrosesan Text-to-Speech seperti pada model Tacotron2 ataupun pada pemrosesan Audio Speech Recognition untuk bahasa Indonesia.
HIV infection in newborns – laboratory diagnosis
Authors:   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, Toader Mioriţa , Ştefan Olivia ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, Şerbănică Andreea ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, Neacşu Daniela ,   Institutul Naţional de Geriatrie „Ana Aslan“, Bucureşti, Drăghici Mircea ,   Dentirad Hospital Ploieşti, Toader Corneliu ,   INNBCV Bucureşti
Published: August 2021

AIDS was reported in the pediatric population for the first time in 1982 in the USA by pediatricians who hardly managed to convince those responsible for childcare, because it can also occur in this population segment. Thanks to efforts for disease recognition in the pediatric population, scientists have been able to provide support and children infected with human immunodeficiency virus (HIV) receive the same treatment protocol as adults. Early detection of HIV infection in pregnant women leads to the possibility for starting a treatment to prevent HIV transmission from mother to child. The ELISA test has a high sensitivity and is indicated for HIV screening and Western Blot test has highly specificity and confirming the HIV infection.
Respiratory infection genetics
Authors:   Facultatea de Medicină Universitatea Transilvania Braşov, Buzinschi Sorin
Published: August 2021

Genetic epidemiology and twin studies argue that genetic differences contributes to evolution and gravity of infections. Changes of Toll-like Receptors, proinflammatory cytokines, immunity genes in different clinical situations confirms the importance of genetic factors and suggest the importance of nongenetic factors (epigenetic) in evolution and gravity of diseases.
Pulmonary superinfection with multidrug-resistant germs in a patient with immunocompromised status
Authors:   Clinica ATI, Spitalul Universitar de Urgenţă, Bucureşti, Tudor Cristina Anca , Petre Raluca ,   Clinica ATI, Spitalul Universitar de Urgenţă, Bucureşti, Chatzifilippidou Christina ,   4th Health Regional Authority of Macedonia and Thrace, Health Unit of Toumpa first degree national health network (PEDY), Nica Adrina Elena ,   Clinica ATI, Spitalul Universitar de Urgenţă, Bucureşti,   UMF „Carol Davila“, Bucureşti
Published: August 2021

Infection with multidrug-resistant germs occurs in certain population at risk, usually in patients admitted in intensive care and is characterized by a high mortality. This paper presents the case of a patient with immunocompromised status witch associate a community lung infection with multiresistant gram-negative bacteria pneumonia. Fast bacteriological identification of the germs involved in lung infection allowed modification of antibiotic approach and a favorable outcome.
MANAGEMENTUL INFECȚIEI CU VIRUS HEPATITIC B ÎN LEGĂTURĂ CU REPRODUCEREA UMANĂ
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România, Gherlan George
Published: August 2021

Infecția cu VHB este o problemă importantă de sănătate publică. Se estimează că la nivel mondial 2 miliarde de oameni prezintă markeri serologici ce atestă trecerea prin această infecție. În majoritatea cazurilor de infecție VHB contractată la vârsta adultă, evoluția naturală este către clearance-ul AgHBs (ceea ce nu este totuși echivalent în toate cazurile cu vindecarea completă, virusul putând persista sub forma de ccc ADN în celulele hepatice). Situația este complet diferită, însă atunci când infecția survine în perioada perinatală intrapartum sau post-partum și mai rar intrauterin), acești pacienți evoluând mai frecvent către forme cronice de infecție ce pot fi active, inactive sau sub formă de imunotoleranță. Transmiterea materno-fetală reprezintă principala problemă în ceea ce privește managementul infecției VHB în sarcină. În această trecere în revistă a datelor din literatură am sintetizat datele referitoare la impactul infecției VHB asupra sarcinii, dar și a sarcinii asupra infecției VHB. Am căutat de asemenea date cu privire la posibilitatea transmiterii paterno-fetale a infecției și am încercat să clarific mecanismele prin care infecția ajunge să fie transmisă, pentru ca în cele din urmă să sintetizez recomandările existente cu privire la managementul infecției cu VHB în legătură cu reproducerea umană sub forma unor algoritmi care să ușureze activitatea medicului de boli infecțioase pus în fața unei astfel de situații.
MATERNAL INFECTION WITH PARVOVIRUS B19 LEADING TO FETAL HYDROPS AND INTRAUTERINE DEATH – CASE PRESENTATION
Authors:   University of Medicine and Pharmacy Tîrgu Mureș, Department of Obstetrics and Ginecology I, Claudiu Mărginean , Lucian Pușcașiu ,   University of Medicine and Pharmacy Tîrgu Mureș, Department of Obstetrics and Ginecology I, Claudiu Molnar Varlam ,   University of Medicine and Pharmacy Tîrgu Mureș, Department of Obstetrics and Ginecology I, Cosmin Rugină ,   The County hospital Piatra Neamț – Department of Obstetrics and Ginecology
Published: August 2021

Parvovirus B19 belongs to the Parvoviridae family, Erythrovirus type, and it presents cytotoxicity on the erythroblast human line leading to severe anemia. We present the case of a 35-year-old woman, at the 3rd pregnancy, with a first trimester abortion in her history and a physiological birth, who presented to the specialty check-up at 20 gestational weeks, associating the signs of a respiratory infection, without any other pathologies until this gestational age. The laboratory tests and the fetal ultrasound did not point out any pathological elements, therefore the patient was sent home with the recommendation to come back after 2 weeks for reevaluation, when the fetal ultrasound revealed fetal hydrops and severe anemia, and after 24 hours fetal asystole. Maternal serology pointed out recent infection with Parvovirus B19. The particularity of this case consists in the appearance of relative rare fetal infection in the second trimester of pregnancy in the case of a physiological, monitored pregnancy, with unfavorable prognosis and fulminant death towards intrauterine death.
THE INFECTION WITH HELICOBACTER PYLORI FAVORS THE PRESENCE OF GIARDIA LAMBLIA IN THE GASTRIC MUCOSA – CASE PRESENTATION
Authors:   Pediatrics Clinic 1 Târgu Mureș, Elena Meliț Lorena ,   University of Medicine and Pharmacy Târgu Mureș, Mărginean Cristina Oana ,   Pediatrics Clinic 1 Târgu Mureș,   University of Medicine and Pharmacy Târgu Mureș, Mocan Simona ,   Department of Pathology Târgu Mureș, Suciu Nicoleta ,   University of Medicine and Pharmacy Târgu Mureș, Mărginean Maria Oana ,   Pediatrics Clinic 1 Târgu Mureș
Published: August 2021

Helicobacter pylori and Giardia lamblia are common worldwide. Helicobacter pylori is a favoring factor for the presence of Giardia lamblia in the stomach due to the neutralization of the gastric pH through the secretion of urease. We present the case of a 5-year-old child, with intermittent gastro-intestinal symptoms in the recent personal pathological history, admitted in the Pediatrics Clinic 1 Târgu Mureș for abdominal pain, nausea, loss of appetite and hematemesis. The superior digestive endoscopy revealed multiple hemorrhagic lesions of the gastric mucosa, and the pathological exam of the antral gastric mucosa identified the coexistence of Helicobacter pylori and Giardia lamblia. The evolution of the patient was favorable under the eradication therapy of the infection with Helicobacter pylori and the antiparasitic drugs, the control endoscopy revealing a gastric mucosa without macroscopically obvious modifications, and the pathological re-evaluation pointed out regenerative modifications of the gastric mucosa. The particularity of the case is represented by the identification of the parasite Giardia lamblia in the gastric mucosa, a physiologically acid environment, alkalinized by the urease secreted by Helicobacter pylori, therefore providing favorable conditions for the development of this parasite in a 5-year-old child, from a favorable socio-economic environment, with intermittent gastrointestinal symptoms in his recent personal pathological history.
HIV ASSOCIATED LYMPHOMA – TWO CASE REPORT SERIES
Authors:   “Carol Davila’’ University of Medicine and Farmacy, Bucharest, Gavriliu Liana-Cătălina ,   “Prof. Dr. Matei Bals’’ National Institute of Infectious Disease, Bucharest, Benea Otilia-Elisabeta ,   “Carol Davila’’ University of Medicine and Farmacy, Bucharest,   “Prof. Dr. Matei Bals’’ National Institute of Infectious Disease, Bucharest
Published: August 2021

Combined antiretroviral therapy significantly improved the prognosis and the life expectancy of HIV patients. Along with this, the profile of HIV associated malignant pathologies has changed. Among these, lymphoma, with a higher incidence than in general population, are an important cause of mortality and morbidity in HIV infected people. We present two cases of HIV-associated lymphoma. In the first case, a newly HIV diagnosed patient, with a good immunological status, developed non-Hodgkin´s Burkitt-type lymphoma and he had a fulminant evolution towards death. In the second case, a patient known for over twenty years with HIV infection and who had discordant immunological and virusological response to antiretroviral therapy, was diagnosed with Hodgkin´s lymphoma and he had a favorable evolution with chemotherapy. Both patients required exhaustive medical investigations and a close interdisciplinary cooperation during the entire time of diagnostic and therapeutic procedures.
TREATMENTS OF HEPATITIS C VIRUS LIVER CIRRHOSIS WITH PEGYLAT INTERFERON-RIBAVIRIN AND INTERFERON FREE – COMPARATIVE STUDY
Authors:   Team of PN II PT PCCA 88/2011 project, Florescu S.A. , Lazar S. ,   Team of PN II PT PCCA 88/2011 project, Oprea C. ,   Team of PN II PT PCCA 88/2011 project, Motoc A. ,   Team of PN II PT PCCA 88/2011 project, Codreanu D. ,   Team of PN II PT PCCA 88/2011 project, Kosa A.G. ,   Team of PN II PT PCCA 88/2011 project, Ceausu E. ,   Team of PN II PT PCCA 88/2011 project
Published: August 2021

The article describes the adverse effects and efficiency of hepatitis C virus liver cirrhosis treatments available through the National Health Insurance Services, on a population of patients hospitalized at Victor Babes Infectious and Tropical Diseases Hospital, from 2012 to 2016. The population of patients was split into two distinct groups, for which we’ve recorded and comparatively analyzed demographic, clinical and paraclinical characteristics in a database. An evident success was recorded, from the point of view of hitting a clinical SVR index, in the DAA therapy group A, 87% percent compared to 2% in group B for the traditional standard therapy of PegInterferon + Ribavirin. Likewise, the number of adverse effects was lower in Group B versus Group A. Some side effects remained specific to the current cirrhosis treatment, which should be closely monitored.
PNEUMONIA, STILL A CHALLENGE FOR THE PEDIATRICIAN – CASE REPORT
Authors:   University of Medicine and Pharmacy, Targu Mures, Marginean Maria Oana , Marginean Cristina Oana ,   University of Medicine and Pharmacy, Targu Mures,   Pediatrics Clinic No. 1, Targu Mures, Sasaran Vladut ,   University of Medicine and Pharmacy, Targu Mures, Suciu Nicoleta ,   University of Medicine and Pharmacy, Targu Mures, Melit Lorena Elena ,   University of Medicine and Pharmacy, Targu Mures,   Pediatrics Clinic No. 1, Targu Mures
Published: August 2021

Pneumonia represents an inflammation of the pulmonary parenchyma that despite the multiple antibiotic classes available and despite the medical progresses, still leads to an increased mortality rate, especially in children. Deltfia acidovorans and Stenotrophomonas maltophilia are Gram-negative bacilli that can lead to respiratory infections. We present the case of a 2 years and 3-month old male patient, admitted in our clinic for the following reasons: productive cough, fever and loss of appetite. Based on the clinical exam, laboratory and paraclinical investigations, we established the diagnosis of right pneumonia associated with pleural effusion and we administered wide spectrum antibiotics. Nevertheless, the evolution was unfavorable, needing pleurotomy and drainage. From the pleural fluid, there were isolated two strains of bacteria, Delftia acidovorans and Stenotrophomonas maltophilia. We adjusted the antibiotic regimen according to antibiogram, with afterwards slowly favorable evolution. The particularity of the case consists in diagnosing a pneumonia with pleural effusion in a 2 years and 3-month-old child, without risk factors, who needed pleurotomy with thoracic drainage, in whom the pleural fluid revealed 2 germs usually encountered in immunocompromised individuals, with favorable evolution after the initiation of antibiotics regimen according to the antibiogram.
INFECŢIILE ŞI PREMATURITATEA, FACTORI DE RISC IMPORTANŢI AI MORBIDITĂŢII ŞI MORTALITĂŢII NEONATALE
Authors:   Disciplina de Chirurgie şi Ortopedie Pediatrică, Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, Ţarcă Elena , Gavrilescu Simona ,   Disciplina de Chirurgie şi Ortopedie Pediatrică, Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, Florescu Laura ,   Disciplina de Puericultură, Universitatea de Medicină şi Farmacie „Gr. T. Popa” Iaşi, Murgu Alina Mariela ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa” Iaşi, Ungureanu Monica ,   Disciplina de Medicină Preventivă şi Interdisciplinaritate, Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, Lupu Vasile Valeriu ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa” Iaşi, Mîndru Dana Elena ,   Disciplina de Puericultură, Universitatea de Medicină şi Farmacie „Gr. T. Popa” Iaşi
Published: August 2021

Mortalitatea infantilă este o problemă majoră pentru ţările în curs de dezvoltare, dar din păcate şi pentru ţara noastră, deoarece România este pe primul loc în Uniunea Europeană din acest punct de vedere, cu o rată a mortalităţii infantile de 9‰ faţă de media de aproximativ 4‰. La nivel mondial, peste 15 milioane de copii sunt născuţi prematur anual şi dintre aceştia, mai mult de un milion decedează, prematuritatea şi infecţiile fiind principalii factori de risc ai mortalităţii neonatale. Riscul infecţios este de câteva ori mai mare la prematuri decât la nou-născuţii la termen, aproximativ 80% dintre infecţiile neonatale apărând la prematuri. O proporţie importantă a supravieţuitorilor prematurităţii vor rămâne cu sechele neurologice importante din cauza atât a infecţiilor neonatale, cât şi a hemoragiilor intracerebrale sau hipoxiei la naştere. Educaţia medicală continuă, atât în cadrul populaţiei generale cât şi în sectorul medical, este de o importanţă crucială în prevenirea naşterilor premature, a infecţiilor neonatale, şi implicit pentru scăderea ratelor morbidităţii şi mortalităţii infantile în ţara noastră.
PNEUMONIA, O PROVOCARE CONTINUĂ PENTRU PEDIATRU – PREZENTARE DE CAZ
Authors:   Universitatea de Medicină şi Farmacie, Târgu Mureş, Mărginean Maria Oana , Mărginean Cristina Oana ,   Universitatea de Medicină şi Farmacie, Târgu Mureş,   Clinica de Pediatrie Nr. 1, Târgu Mureş, Săsăran Vlăduţ ,   Universitatea de Medicină şi Farmacie, Târgu Mureş, Suciu Nicoleta ,   Universitatea de Medicină şi Farmacie, Târgu Mureş, Meliţ Lorena Elena ,   Universitatea de Medicină şi Farmacie, Târgu Mureş,   Clinica de Pediatrie Nr. 1, Târgu Mureş
Published: August 2021

Pneumonia reprezintă o inflamaţie a parenchimului pulmonar care, în ciuda multiplelor clase de antibiotice disponibile şi în ciuda progreselor medicinei, deţine încă o rată crescută de mortalitate, mai ales în cazul copiilor. Deltfia acidovorans şi Stenotrophomonas maltofilia sunt bacili Gram-negativi care pot determina infecţii respiratorii. Prezentăm cazul unui pacient de sex masculin, în vârstă de 2 ani şi 3 luni, internat în clinica noastră pentru următoarele motive: tuse productivă, febră şi inapetenţă. Pe baza examenului obiectiv, a analizelor de laborator şi a investigaţiilor imagistice, am stabilit diagnosticul de pneumonie dreaptă asociată cu pleurezie şi am instituit antibioterapie cu spectru larg. Evoluţia a fost însă nefavorabilă, pacientul necesitând pleurostomie şi drenaj. Din lichidul pleural au fost izolaţi Delftia acidovorans şi Stenotrophomonas maltophilia. Am modificat schema de tratament conform antibiogramei, cu evoluţie ulterioară lent favorabilă. Particularitatea cazului constă în diagnosticarea unei pneumonii cu pleurezie la un copil în vârstă de 2 ani şi 3 luni, cu un episod de pneumonie în antecedente, fără factori de risc, care a necesitat pleurostomie cu drenaj toracic, la care cultura din lichidul pleural a evidenţiat doi germeni întâlniţi de obicei la persoanele imunocompromise, cu evoluţie favorabilă după iniţierea antibioterapiei conform antibiogramei.
ANÁLISE FITOQUÍMICA E DOSEAMENTO DE METABÓLITOS SECUNDÁRIOS DAS FOLHAS DE Miconia albicans (Sw) TRIANA COLETADAS DE DUAS REGIÕES DO ESTADO DE GOIÁS
Authors: Silva Amanda Abreu Oliveira , Figueredo Aparecida Tânia Frazão Barbosa , Santos Pierre Alexandre dos , Belo Emiliane Dos Santos , Souza Maria Juíva Marques de Faria de
Published: August 2021

Introdução: Uma espécie medicinal que está sendo utilizada pela população e que possui poucos estudos científicos na literatura relacionados à análise fitoquímica, bem como variação quantitativa de metabólitos frente a nutrientes disponíveis no solo é a Miconia albicans (Sw) Triana, conhecida popularmente como canela de velho. Objetivo: Determinar o perfil fitoquímico e quantificar os principais metabólitos secundários das folhas de M. albicans coletadas em duas regiões distintas. Metodologia: As folhas de M. albicans foram coletadas no município de Niquelândia-GO e Nova Glória-GO. Posteriormente, as folhas foram secas e trituradas, e realizadas as seguintes análises: prospecção fitoquímica, quantificação de compostos fenólicos, taninos e flavonoides e composição (macro e micronutrientes) do solo entre as duas regiões. Resultados e discussão: As duas amostras, por meio dos ensaios de fitoquímica, apresentaram positivas para flavonoides, saponinas, cumarinas e taninos. Quanto a quantificação de metabólitos, a amostra coletada na região de Niquelândia-GO apresentou maior percentual significativo de compostos fenólicos (29,20 %) e taninos (24,52 %) comparada com a amostra coletada no município de Nova Glória-GO, provavelmente devido à baixa quantidade de minerais e elevada toxidez por alumínio do solo.Conclusão: As folhas de M. albicans coletadas nas duas regiões distintas possuem flavonoides, saponinas, cumarinas e taninos como metabólitos secundários, os quais são responsáveis pelos efeitos antioxidantes, antiinflamatórios, analgésicos e antimicrobianos citados pela população. E a composição do solo, onde o vegetal foi desenvolvido, interfere na produção de metabólitos secundários.Nutrientes
Design Optimization of B-series Marine Propeller using NSGA-II, Iterative and Gekko Algorithm
Authors: Mahtab SM Munawar , Roy Debasish , Rabbi Md. Sanaul , Alam Md. Iftekharul
Published: August 2021

The design of a propeller plays a significant role in naval architecture. Optimization of various design factors is the primary concern for effective and efficient propulsion. This study investigates the optimization of the B-series marine propellers using three different methods, i.e. (i) a non-linear constrained single-objective optimization approach using the Non-Dominated Sorting Genetic Algorithm (NSGA-II), (ii) a python package for dynamic optimization based optimization software ‘Gekko’, (iii) an iterative approach and results were compared with each other. Efficiency is considered as the single objective function whereas three constraints are imposed: cavitation, thrust and strength. Analogous characteristics have been found in the comparison of results from all three methods. Comparing the various factors, this study suggests that, Gekko can be used as the optimization algorithm.
Visible-light Phase Curves from the Second Year of the TESS Primary Mission
Authors: Wong Ian , Kitzmann Daniel , Shporer Avi , Heng Kevin , Fetherolf Tara , Benneke Björn , Daylan Tansu , Kane Stephen R. , Vanderspek Roland , Seager Sara , Winn Joshua N. , Jenkins Jon M. , Ting Eric B.
Published: August 2021

We carried out a systematic study of full-orbit phase curves for known transiting systems in the northern ecliptic sky that were observed during Year 2 of the TESS primary mission. We applied the same methodology for target selection, data processing, and light-curve fitting as we did in our Year 1 study. Out of the 15 transiting systems selected for analysis, seven—HAT-P-7, KELT-1, KELT-9, KELT-16, KELT-20, Kepler-13A, and WASP-12—show statistically significant secondary eclipses and day–night atmospheric brightness modulations. Small eastward dayside hot-spot offsets were measured for KELT-9b and WASP-12b. KELT-1, Kepler-13A, and WASP-12 show additional phase-curve variability attributed to the tidal distortion of the host star; the amplitudes of these signals are consistent with theoretical predictions. We combined occultation measurements from TESS and Spitzer to compute dayside brightness temperatures, TESS-band geometric albedos, Bond albedos, and phase integrals for several systems. The new albedo values solidify the previously reported trend between dayside temperature and geometric albedo for planets with 1500 K < T
day < 3000 K. For Kepler-13Ab, we carried out an atmospheric retrieval of the full secondary eclipse spectrum, which revealed a noninverted temperature–pressure profile, significant H2O and K absorption in the near-infrared, evidence for strong optical atmospheric opacity due to sodium, and a confirmation of the high geometric albedo inferred from our simpler analysis. We explore the implications of the phase integrals (ratios of Bond to geometric albedos) for understanding exoplanet clouds. We also report updated transit ephemerides for all of the systems studied in this work.
Observations of the Bright Star in the Globular Cluster 47 Tucanae (NGC 104)
Authors: Dixon W. V. , Chayer Pierre , Miller Bertolami M. M. , Sosa Fiscella S. V. , Benjamin R. A. , Dupree A.
Published: August 2021

The Bright Star in the globular cluster 47 Tucanae (NGC 104) is a post-asymptotic giant branch (post-AGB) star of spectral type B8 III. The ultraviolet spectra of late-B stars exhibit myriad absorption features, many due to species unobservable from the ground. The Bright Star thus represents a unique window into the chemistry of 47 Tuc. We have analyzed observations obtained with the Far Ultraviolet Spectroscopic Explorer, the Cosmic Origins Spectrograph aboard the Hubble Space Telescope, and the Magellan Inamori Kyocera Echelle Spectrograph on the Magellan Telescope. By fitting these data with synthetic spectra, we determine various stellar parameters (T
eff = 10,850 ± 250 K,

log
g
=
2.20
±
0.13

) and the photospheric abundances of 26 elements, including Ne, P, Cl, Ga, Pd, In, Sn, Hg, and Pb, which have not previously been published for this cluster. Abundances of intermediate-mass elements (Mg through Ga) generally scale with Fe, while the heaviest elements (Pd through Pb) have roughly solar abundances. Its low C/O ratio indicates that the star did not undergo third dredge-up and suggests that its heavy elements were made by a previous generation of stars. If so, this pattern should be present throughout the cluster, not just in this star. Stellar-evolution models suggest that the Bright Star is powered by a He-burning shell, having left the AGB during or immediately after a thermal pulse. Its mass (0.54 ± 0.16M
⊙) implies that single stars in 47 Tuc lose 0.1–0.2 M
⊙ on the AGB, only slightly less than they lose on the red giant branch.
Search for Collisionally Pumped 1720 MHz OH Masers in Star-forming Regions: A VLA Survey of 18 cm OH Masers toward 80 Class I Methanol Masers
Authors: Bayandina O. S. , Val’tts I. E. , Kurtz S. E. , Shakhvorostova N. N.
Published: August 2021

Class I methanol masers (cIMMs) and 1720 MHz OH masers are believed to arise from a common collisional pumping mechanism, and both trace shocked gas regions in supernova remnants (SNRs). However, their coexistence in star formation regions (SFRs) and their association with a front of bipolar outflow (a source of shock-stimulated collisional pumping) remain unclear. To search for collisionally pumped OH(1720) masers, we conducted a Very Large Array survey of the 18 cm OH masers and continuum emission toward a sample of 80 SFRs associated with 44 GHz cIMMs. Main-line OH maser emission was detected in 50% of the sample, and OH(1720) maser emission was detected in 20%. Continuum emission was detected in 28% of sources. A catalog of the detected OH masers is presented. Individual OH masers are found in close proximity, and the regions of masers of different transitions are often overlapping. A typical linear projected offset between the OH(1720) and OH(1665) masers is ∼0.04 pc. A remarkable number of ∼81% of the OH(1720) masers are associated with the continuum emission. The median separation between the targeted 44 GHz cIMMs and OH(1720) masers is ∼0.2 pc, which is similar to reported distances between cIMMs and H ii regions. The observed properties of the detected OH(1720) masers are different from those in SNRs and indicate that a nonlocal line overlap mechanism is responsible for their excitation. Thus, while both 44 GHz cIMMs and OH(1720) masers trace shocked gas in SNRs, physical conditions favorable for excitation of cIMMs, but not OH(1720) masers, are present in SFRs.
Autogenous Onlay Graft with Compression Plate for Treatment of Persistent Humeral Shaft Aseptic Non-union with Failed Previous Surgery
Authors: Hashmi Falih Waheed , Al-Shara Mohammed Baqir , Al-Edanni Mohammed
Published: August 2021

BACKGROUND: The humeral shaft fractures have a good rate of union, despite this fact, still there is a significant rate of nonunion after nonoperative treatment and more often after operative treatment.

AIM: The aim of the study is to evaluate the autogenous onlay graft with compression plate for treatment of persistent humeral shaft non-union with failed previous surgery both radiological and functional outcome.

MATERIALS AND METHODS: A prospective study on twenty patients having persistent aseptic non-union age between 20 and 60 years old, after failed surgical treatment of fractures humeral shaft in Al-Zahra teaching and Al-Kindy teaching hospitals, while infected nonunion, diabetes mellitus, secondary metastasis, smoking, alcoholism, and patients on long medication with corticosteroid were excluded from the study. All our patients were treated with corticocancellous onlay bone grafting harvesting from the ipsilateral upper tibia and compression plating (graft parallel to plate) and follow-up for at least 18 months post-operative to evaluate both radiology and functional using Mayo elbow performance index.

RESULTS: All the patients ended with a solid union without hardware failure, and no one patient needs further surgery, even with significant resorption of the graft, there is a good chance of graft re-calcification and solid union with good to excellent functional outcome.

CONCLUSION: Very successful solid union results achieve in those patients with established aseptic nonunion and pseudoarthrosis of the humerus.
Comparison of Two Generations of Systems for Digital Occlusion Examination
Authors: Bozhkova Tanya
Published: August 2021

BACKGROUND: The modern concept of occlusion includes the relationship between teeth, masticatory muscles, and temporomandibular joints in function and dysfunction. Occlusion can be defined very simply: it means the contacts between teeth. Qualitative and quantitative methods are used to register and evaluate occlusal contacts. The T-Scan handpiece model was updated in 2015 as T-Scan Novus (software version 9.1) and the latest updated one being the T-Scan version 10 software introduced in 2018.

AIM: The purpose of this study is to demonstrate the capabilities and results of two generations of systems - T-Scan III and T-Scan Novus.

MATERIALS AND METHODS: For the realization of the set goal, the occlusion of a patient with the initials S.K. is examined with two systems. The patient is 43 years old with intact teeth, Angle’s class I jaw relation. The study with T-Scan III was conducted in 2015 and with T-Scan Novus in 2019.

RESULTS: The software of both systems uses a graphical interface, which transforms the data obtained during the recording of the occlusion as the model of the upper dentition of the patient in T-Scan III and the upper and lower dentition in T-Scan Novus. Registered occlusal contacts are illustrated as 2D and 3D images of different colors. The graph force/time shows the power versus time from the first contact to the end of the movie. The timing table displays the patient’s total occlusal bite timing, and the force applied. T-Scan Novus software allows you to import digital fingerprint files of the upper and lower dentition in.stl format.

CONCLUSION: The software program of the system version 9.1 provides better visualization of dental arches making it much more informative than other versions. The T-Scan system allows fast and accurate registration and analysis of occlusion.