bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparing the Versatility of Anterolateral Thigh (ALT) Free Flap and Superficial Circumflex Iliac Artery Perforator (SCIP) Free Flap for Hand Reconstruction Due to Electric Burn Injuries: Case-Based Literature Review
Authors:   Burn Unit, Pertamina Central Hospital, Jakarta, Indonesia, Azizah Sarah , Sandhi Afriyanti ,   Burn Unit, Pertamina Central Hospital, Jakarta, Indonesia, Fawzy Ahmad ,   Department of Surgery Faculty of Medicine University of Jenderal Soedirman – Margono Soekarjo County Hospital, Indonesia
Published: December 2024

Electrical injuries, often caused by high-voltage currents from sources like arc flashes or ignited clothing, frequently result in extensive burns, particularly to the hands. The upper extremities, being common contact points for electrical injuries, are susceptible to severe tissue damage, including burns, nerve, muscle, and vascular damage. High-voltage electrical burns often require surgical intervention, with an emphasis on restoring both function and form. This study aims to compare the effectiveness of two free flap techniques—Anterolateral Thigh (ALT) and Superficial Circumflex Iliac Artery Perforator (SCIP)—in the reconstruction of hand burns resulting from electrical injuries.

Authors conducted a literature review based on cases from the burn unit at Pertamina Central Hospital, Jakarta, focusing on two patients who underwent reconstruction using the ALT and SCIP free flaps. The ALT free flap, characterized by its versatile and reliable tissue coverage, was utilized in one case, while the SCIP free flap, known for its thin and pliable tissue, was employed in the other. The study reviews the anatomy, advantages, and limitations of each flap, considering factors such as functional outcomes, aesthetic results, donor site morbidity, and surgical complexity. Both techniques were shown to offer significant benefits in reconstructing complex burn injuries, with the ALT flap providing robust coverage and the SCIP flap offering superior contour and functional outcomes for smaller defects.

The findings underscore the versatility of both flaps in electrical burn reconstruction, highlighting the importance of choosing the appropriate technique based on the size and location of the defect. This study contributes valuable insights into the selection of free flap techniques for reconstructing hand injuries caused by electrical burns, aiming to optimize patient outcomes in terms of both functionality and aesthetics.
Future Parliamentary Threshold after the Constitutional Court Decision and the Shadow of The Government's Grand Coalition
Authors:   Master of Law student, Diponegoro University, Semarang., Wibowo Aditya , Herawati Ratna ,   Lecturer at the Faculty of Law, Diponegoro University, Semarang.
Published: December 2024

Parliamentary threshold is the threshold of votes used to decide whether a political party gets a seat in the Indonesian House of Representatives. Historically, parliamentary threshold has experienced a change in numbers starting from 2.5% in the 2009 Election to 4% in the 2024 Election. This study uses normative legal research. Data was collected through literature studies (library research) and analyzed descriptively analytically. The Constitutional Court's decision stated parliamentary threshold conditionally unconstitutional results in the parliamentary threshold in the 2029 Election having to be reviewed. Changes to the parliamentary threshold are in the shadow of the current grand coalition in the Indonesian House of Representatives. So the parliamentary threshold that will be reviewed in the 2029 Election could remain at 4% or more than 4% in accordance with the agreement made in the grand coalition of the Indonesian House of Representatives for the 2024-2029 period. This is reinforced because the Constitutional Court's decision only ordered a review, but did not rigidly order the current parliamentary threshold to be lowered.
Racism through Ifemelu and Trevor in Americanah (2013) and Born a Crime:Stories from a South African Childhood (2016)
Authors:   Cheikh Anta Diop University, Postcolonial and African Studies Laboratory, English Department, Dakar, Senegal, BP : 5005, IKAPI Dr. Fabrice Lié
Published: December 2024

This research paper examines the issue of racism through a comparative analysis of Chimamanda Ngozi Adichie’s Americanah (2013) and Trevor Noah’s Born a Crime (2016). Supporting the analysis on Critical Race Theory as a reference framework, the paper investigates how the protagonists, Ifemelu and Trevor, confront, face and resist racial discrimination within their respective socio-political contexts meaning the United States and South Africa. Thus, this analysis lays emphasis on the personal stories of thjese two characters, the historical and social contexts of racism and the formation of their racial identities. Also, by discussing the unique and shared experiences of these characters, the article aims at contributing in the analysis of the intracacies of racism and the various means to challenge and resist it.
Review of microclimate mapping methods in forestry
Authors: Sánchez-Chero Manuel , Sánchez-Chero José , Flores-Mendoza Lesly , Janampa Felix , Cesare Mary
Published: December 2024

The study of microclimates provides a several benefits that imply their importance to reduce the effects of climate change, so the mapping of microclimates emerges as an alternative for their identification and conservation. The objective of this review is to identify the techniques used in microclimate mapping. The methodology used was an exploratory review in databases such as Science Direct, Springer and IEEXplore, which determined that there is a shortage of works related to microclimate mapping, since only 19 works met the inclusion requirements of the review. It was determined that the main objective of the microclimate mapping focused on the tree canopy, the height and density of the forest structures and their effects on the climatic factors that comprise them. On the other hand, the microclimate mapping methods identified were divided into photogrammetric methods and laser scanning methods, where most of the studies were based on obtaining aerial data, either by drones (UAV, UAS, RPA, RPAS) or airplanes as in the case of airborne LiDAR technologies. It was concluded that there is little research on microclimate mapping, so the forestry scientific community is exhorted to employ the different methodologies for objectives of great impact on the environment such as the prediction of forest fires and the monitoring of forest restoration after these fires.
Multidimensional Trade Theory and Ramsey Effects: Biological Metabolism as Experimental Test on Sustainable Life Expectancy
Authors:   Economic Department at University of Lome /American Institute of Africa/University of Poitiers (France), Edgeweblime Kcodgoh L
Published: December 2024

In this paper the following question is answered: Is the sustainable growth or optimal life expectancy generated by the constancy of the production
possibilities frontier (PPF)? At this end, I study the effects of growth volatility — a perturbation in the PPF of a given economy (human organism)—on
growth’s sustainability. I use a laboratory experiment’s results and propose a theory to address this issue. I find the human organism's multidimensional
exchange mechanism, consisting of more or less integral compensation processes for negative and positive externalities, is responsible for the volatility of
human growth, the main determinant of life expectancy, analogous in principle to the relationship between the processes of economic growth volatility
and sustainability. Because the analogy is established the PPF appears to be the sole determinant of the sustainability of economic growth (life expectancy).
Ser professor-autor: imaginário em funcionamento em um curso de formação continuada de professores
Authors: Capitanio Alâna , Stübe Angela Derlise , Luz Mary Neiva Surdi da
Published: December 2024

Neste artigo analisamos que imaginário de professor-autor circula em um texto de referência de um curso de formação continuada de professores para o Ensino Médio, conforme a perspectiva teórico-metodológica da Análise de Discurso Franco-brasileira, mobilizando as noções de autor, autoria e imaginário. O corpus da pesquisa se constitui pelo texto de referência do curso de formação continuada, Núcleo de autoria e criação docentes, a partir do recorte da marca linguístico-discursiva “professor-autor”. Compreendemos que o imaginário de professor-autor que emerge do corpus é de um professor-autor prático, fazedor de aulas, gestor de situações de aprendizagem que ampliam e otimizam tempos e resultados. Esses sentidos vinculam-se à formação discursiva mercadológica inserida em uma formação ideológica neoliberal que visa à produtividade e à supervalorização da prática em detrimento da práxis, silenciando outros modos de constituição do professor como autor.
Effect of economic recession on the food purchasing behaviour of people of Karachi
Authors: Thaver Inayat Hussain , Ahmed Sheikh Farooq , Suri Hafsa Adnan , Qureshi Muhammad Abu Bakar Irfan , Ahmed Atique , Kabani Areesh Akbar
Published: December 2024

Economic recessions, extending beyond macro indicators, profoundly impact individual consumers and their food-purchasing behaviour. This study examines how people in Karachi, Pakistan, purchase food and how the recession has affected that activity. Data from 384(100) participants were gathered using the cross-sectional study method in a survey. The sample size was calculated, keeping the confidence level at 95%, with a 5% margin of error. Results highlight significant shifts in purchasing behaviour, with many respondents opting for more economical food choices and reducing spending on non-essential items. Crucially, household size and income level emerged as predictors of these changes. The findings carry implications for legislators and stakeholders, providing insights into food consumption dynamics during economic uncertainty. The study emphasizes the need for targeted policies to navigate the intricate web of individual and familial dietary choices amid economic downturns.
Keywords: Economic recession, Food insecurity, Humans, Uncertainty
Clinical presentation and management of Tolosa-Hunt syndrome: a case report
Authors: Bisma Qasim  , Farnaz Siddiqui  , Maria Saleem  , Muhammad Zohaib  , Muhammad Khuzzaim Khan  , Nisar Ahmed Siyal
Published: December 2024

Tolosa-Hunt Syndrome (THS) is an exceptionally rare disorder characterised by recurrent episodes of excruciating ophthalmoplegia, commonly affecting one side of the face and involving the third, fourth, sixth, and fifth cranial nerves. This syndrome results from non-specific inflammation affecting the cavernous sinus, superior orbital fissure (SOF), and/or orbital apex. In this case report, we present the clinical features, diagnostic evaluation, and management of a 46-year-old female with THS. The patient initially presented with right-sided peri-orbital pain, swelling, chemosis, and headache. Ocular examination revealed mild to moderate proptosis, complete ophthalmoplegia, and normal findings in the left eye. Imaging studies, including CT and contrast-enhanced MRI, confirmed the presence of non-specific inflammation in the cavernous sinus and associated structures. Immediate treatment with oral Prednisolone led to a significant reduction in symptoms within five days, with complete resolution of chemosis and pain. Ocular movements gradually improved over the following week. Long-term follow-up showed no recurrence of symptoms.
Keywords: Chemosis; Ophthalmoplegia; Cavernous Sinus.
The lymphocele conundrum: incidence and management in early renal transplants
Authors: Abdul Ahad Usman , Mahar Naveed Ahmed , Hassan Qureshi Harris , Kalwar Sara
Published: December 2024

Objective: To assess the incidence of post-transplant lymphocele, identify risk factors, and analyse the effectiveness and outcomes of different management approaches.
Method: The prospective, descriptive study was conducted at the Department of Renal Transplant, Sindh Institute of Urology and Transplantation, Karachi, from February 25, 2021, to December 25, 2022, and comprised transplant patients. Ultrasound was performed in all patients presenting with symptomatology attributed to lymphocele. Any peri-graft collection was labelled as lymphocele if creatinine level of aspirated fluid was similar to that of serum creatinine level of the patients. Data was analysed using SPSS 23.
Results: Of the 300 patients, 230(76.7%) were males and 70(23.3%) were females. The overall mean age was 37.33±8.70 year. There were 18(6%) patients with diabetes, 248(82.7%) with hypertension and 38(12.7%) were obese. The frequency distribution of lymphocele was observed in 22(7.3%) patients, and the mean diameter of lymphocele was 12.50±1.68 cm.
Conclusion: Lymphatic complications, particularly lymphocele, continue to pose a surgical challenge in kidney transplant recipients, primarily resulting from the extensive dissection of the lymphatics during the transplantation procedure.
Key Words: Lymphocele, Renal transplantation, Chronic kidney disease.
Knowledge, attitudes, and anxiety levels of parents with suspected COVID-19 children: A cross-sectional study in Turkey
Authors: Konukbay Dilek , Kapan Emine , Yildiz Dilek , Unay Bulent
Published: December 2024

Objective: To determine the knowledge, attitudes and anxiety levels of parents with children suspected of having coronavirus disease-2019.
Method: The descriptive, cross-sectional study was conducted at the coronavirus disease-2019 outpatient clinic of a tertiary hospital in Ankara, Turkey, between January and August 2021, and comprised parents who presented with suspicions of coronavirus disease-2019 in their children. Data was collected using a questionnaire to assess the parents' knowledge and attitudes towards coronavirus disease-2019, the State-Trait Anxiety Inventory-I and the visual analogue scale to determine levels of fear related to coronavirus disease-2019. Data was analysed using SPSS 25.
Results: Of the 307 subjects with mean age 40.53±8 years (range: 22-68 years), 237(77.2%) were mothers, 125(40.7%) were high school graduates and 130(42.3%) were employed. The mean score for fear of infection in the children was 7.95±2.64 (range: 0-10, while the mean score for fear of infection of self and other family members was 7.79±2.63 (range: 0-10). The mean scores for knowledge and attitude towards coronavirus disease-2019 were 24.93±4.05 (range: 6-30) and 64.86±26.53 (range: 18-90), respectively. The mean anxiety score was 39.74±7.27 (range: 20-80). There was a significant relationship of knowledge and attitude towards coronavirus disease-2019 with the mother-father status, age and education levels of the participants (p<0.05). There was also a significant relationship of anxiety with the mother-father status and employment status of the parents (p<0.05).
Conclusion: Parents had a high level of knowledge about coronavirus disease-2019, a positive attitude towards protective measures, and a moderate level of anxiety. They had a high level of fear of transmitting the disease to themselves, their children and other family members.
Key Words: COVID-19, Attitude, Knowledge, Anxiety.
Challenges in practice and training structure of residents in obstetric anaesthesia: a perspective from teaching hospitals in Sindh province of Pakistan
Authors: Khan Fauzia Anis , Haider Saeeda , Abbas Nighat , Khaskheli Saleh , Soomro Ahmed Uddin , Siddiqui Safia Zafar
Published: December 2024

Objective: To document information on the available obstetric anaesthesia services and structure of resident training in a Pakistani setting.
Method: The survey was conducted from June to September 2018 across the Sindh province of Pakitan after approval from the ethics reiew committee of the Pakistan Society of Anaesthesiology, and covered all teaching hospitals in both public and private sectors recognised for residents’ training for fellowship in Anaesthesiology by the College of Physician and Surgeons of Pakistan. A standardised questionnaire was filled by either the department chairperson or a senior designated faculty member in each institution regarding obstetric anaesthesia services and structure of resident training. Data was analyse using SPSS 22.
Results: The results reflect the obstetric anaesthesia practice in 12 teaching institutions of Sindh province, seven government-run, and five private. Only 2 (17%) hospitals had dedicated preoperative assessment clinics for obstetric patients. Epidural service for pain free labour was available in 8(67 %) of the hospitals. Eleven (91.6%) hospitals had dedicated operating rooms and nine (75%) had separate recovery facilities.  Onsite laboratory and blood banks were available in only 3(42%) of government and 3(60%) of private institutions. In 9( 75%) hospitals staffing of these units were by Senior Medical Officers. Regarding training of residents, a shortage of trainers was observed in two government and one private hospital leading to unsupervised work by the trainees. There was wide variation in training in spite of a standardised curriculum provided by the national training body.
Conclusion: Gaps were identified in the practice of obstetric anaesthesia and structure of residents’ training. It is important to improve both service and training to improve patient safety.
Key Words: Pregnancy, Blood, Anesthesia, Obstetrical, Surgeons, Obstetric
Insulinoma; a diagnostic challenge: a case report
Authors: Rafaey Wania , Alvi Asim Munir , Aslam Sidra , Siddiqui Ahmed Imran , Shafiq Waqas
Published: December 2024

Insulinoma is a pancreatic neuroendocrine tumour that primarily leads to episodes of hypoglycaemia due to inappropriate and excessive secretion of insulin. It classically presents with neuroglycopenic and autonomic sympathetic symptoms, which resolve promptly with glucose administration. Elevated level of insulin and C-peptide in the presence of low plasma glucose level and absence of plasma sulfonylurea are diagnostic features. Localisation of the tumour is essential before surgery. However, Insulinoma is difficult to diagnose due to its ambiguous location and insidious course. This is the case of a young male who had 6 months history of adrenergic and neuroglycopenic symptoms, including one episode of seizure. His symptoms resolved with the consumption of high glycaemic indexed food. Biochemical tests were suggestive of insulinoma, but non-invasive imaging techniques including computer tomography (CT) and magnetic resonance imaging (MRI) could not localise the tumour. In this case, pancreatic insulinoma was localised by endoscopic pancreatic ultrasound (EUS). He underwent successful resection of the tumour and his symptoms resolved completely post-surgery.
Keywords: Insulinoma, insulin levels, endoscopic ultrasound.
Molecular profiling of BRCA1/BRCA2 gene variants in Pakistani breast cancer patients
Authors: Ghulam Bushra , Muhammad Afzal  , Amena Rahim  , Zahira Bashir  , Naila Zakria  , Ahmad Abubakr
Published: December 2024

Objective: To determine the frequency of genetic variants in breast cancer types 1 and 2 gene in breast cancer Pakistani patients.
Method: The case-control study was conducted at the Islamic International Medical College and Pakistan Railway Hospital, Rawalpindi, Pakistan, from October 2022 to August 2023, and comprised females with breast cancer in group A, with an age range of 23–83 years (mean 51.9 years with SD ± 10.8 years) and as many healthy, age-matched female controls in group B, with age range of 26–82 years (mean 57.8 years with SD ±10.1 years). Peripheral blood samples were taken from all the participants. Allele-specific tetra amplification refractory mutation system-polymerase chain reaction was used to determine the frequency of c.4485G>A, c.4508C>A, c.5278G>C and c.5503C>T genetic variants in breast cancer type 1 gene, and c.92G>A and c.3109C>T genetic variants in breast cancer type 2 gene. Data was analysed using SPSS 27.
Results: Of the 336 female participants 168(50%) were in each of the 2 groups. None of the group B controls had genetic variants in breast cancer type 1 and 2 genes. In group A patients, 4(2.3%) had the variant c.4485G>A in breast cancer type 1 gene, while other breast cancer type 1 variants were negative. Also, 9(5.3%) group A patients had variants c.92G>A and c.3109C>T in breast cancer type 2 gene.
Conclusion: Cost-effective, polymerase chain reaction-based genetic testing could effectively identify mutant variants of breast cancer types 1 and 2 genes in the Pakistani population.
Key Words: Breast cancer, BRCA1, BRCA2 genes, Allele-specific ARMS-PCR, Genetic testing.
Advancements of AI in healthcare: a comprehensive review of ChatGPT’s applications and challenges
Authors: Ali Sara , Aslam Atrubah , Tahir Zarmeen , Ashraf Bashair , Tanweer Afifa
Published: December 2024

The rapid integration of artificial intelligence into healthcare has introduced transformative possibilities and challenges. The current narrative review was planned to explore diverse applications of Chat Generative Pre-Trained Transformer (ChatGPT) across medical domains, ranging from dietary planning and disease management to medical education and clinical decision support. A comprehensive analysis of ChatGPT's healthcare applications was conducted between July and September 2023, reviewing literature from prominent medical journals and databases, including PubMed, Embase, Cochrane library and the Cumulated Index in Nursing and Allied Health Literature. The studies revealed notable limitations, including inaccuracies, bias and potential safety concerns. Quantitative data highlighted ChatGPT’s high accuracy rates in disease detection, nutrient sufficiency in ChatGPT-generated diet plans and various medical scenarios. The predominantly quantitative evaluations might overlook nuanced qualitative aspects, such as users' perceptions, experiences and ethical concerns. Studies often focus on specific domains, potentially limiting generalisability.
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Evaluation of surgical outcomes of nephron-sparing surgery in a leading hospital of an advanced nation
Authors: Nusrat Nadeem Bin , Walsh Kilian , Frank Darcy  , Garrett Durkan  , Asadullah Aslam  , Imtiaz Saira
Published: December 2024

Objectives: To assess the efficacy of renal score grading in guiding therapy decisions, predicting perioperative outcomes, and characterising tumours following partial nephrectomy.
Methods: The retrospective, single-centre study was conducted at the University College Hospital Galway, Ireland, and comprised data from January 11, 2012, to June 17, 2016, of all patients aged >18 years who underwent partial nephrectomy as part of treatment for kidney cancer. Data was analysed using SPSS 20.
Results: Of the 76 patients, 52(68.4%) were males and 24(31.6%) were females. The median age of patients was 58 years (IQR: 16). Tumours were predominantly on the right side 44(57.9%) and lower pole 36(47.4%), with a median tumour size of 2.35 cm (IQR: 1.0 cm), and renal score had a median of 5.00 (IQR: 2). Of the total, 70(92.1%) patients underwent open surgery, with complications in 6(7.9%), which were associated significantly with higher body mass index, American Society of Anaesthesiologists classification score, warm ischemia time and tumour size (p<0.05). Recurrence correlated with tumour size and positive margins (p<0.05). Survival analysis showed a median disease-free survival (DFS) of 30 months (IQR: 6 months). However, due to the absence of events, the median overall survival (OS) and survival estimates could not be fully calculated. The longest follow-up time was 36 months, with no recorded mortality in the cohort.
Conclusion: For individuals with comparatively small localised renal tumours, the selection of partial nephrectomy was found to be a suitable alternative, showcasing exceptional results regarding the complication profile, recurrence-free survival and overall survival.
Key Words: Nephron Sparing surgery, Partial nephrectomy, Small renal masses, Renal score, Perioperative outcomes.
From paper to pixels: EMR as the solution to prescription errors in Pakistan
Authors: Memon Areeba , Memon Minahil , Memon Dua Mahfooz
Published: December 2024

A prescription is a written directive that outlines instructions for medication administration, including dosage, formulation, route, frequency, and duration. It is dispensed to patients following a physician's consultation and forms the cornerstone of their treatment plan. Any deviation from this plan due to errors constitutes a prescription error, a preventable adverse event related to inappropriate deliverance of information in one or more aspects.1 While developing nations have swiftly transitioned to computer-based prescription systems, through Electronic Medical Records (EMRs), resource-constrained countries like Pakistan still lag In one Asian study, it was found that the distribution of errors differed significantly between handwritten and electronic prescriptions, with rates of 35.7% and 2.5%, respectively.2
Although the use of EMR systems has gained momentum in Pakistan, particularly in private-sector hospitals, their adoption still needs to be improved in public-sector practices. Handwritten prescriptions increase the risk of errors, particularly in busy tertiary care hospitals where healthcare staff are overwhelmed by patient volumes. Illegible handwriting, communication lapses, and confusion stemming from similar drug packaging and names compound these risks. This limitation not only compromises the readability of prescriptions but also hampers medication reconciliation processes, potentially leading to serious drug interactions and compromised patient histories.
EMR systems offer numerous benefits, including a standard template with a forcing function incorporated for fields such as drug dosing, administration route, duration, and allergy information, as well as access to Prescription Drug Monitoring Programs (PDMPs) to identify potential drug-seeking behaviour. Considering Pakistan's low health literacy rate and challenges related to medication adherence and follow-up, EMRs play a crucial role in tracking past medication history and promoting patient adherence. Additionally, they reduce paper waste and the physical space required for storing patient information.
In light of these significant advantages, Pakistan's healthcare must expedite the integration of EMR systems across all medical practices. By doing so, we can enhance patient safety and healthcare quality and contribute to environmental sustainability. This transition minimises paper wastage reduces the ecological footprint associated with printing and storing paper documents, and streamlines administrative processes. Furthermore, EMRs facilitate data analyses and population health management, enabling healthcare providers to make informed decisions and improve healthcare outcomes. Therefore, embracing EMR technology is a step towards modernising healthcare delivery and a responsible action towards preserving our environment for future generations.
Optimizing personalized healthcare using artificial intelligence with precision medicine
Authors: Syed Abdullah Arif
Published: December 2024

Madam,
Precision medicine is a relatively recent approach to managing disease. It considers the genetic, environmental, and lifestyle-related variability unique to each individual, taking into account their predicted response to treatment or their disease risk for prevention strategies [1]. The concept of personalised healthcare to target each individual's medical needs is not exactly new, but the use of emerging technology and innovations, especially in fields like genomics and artificial intelligence (AI), has enabled this model to progress remarkably [2].
The utility of precision medicine for this purpose can be highlighted by pointing out the several domains where individuals can be targeted during the disease management process - for instance, the principles of AI may be used for actions like altering prescriptions based on pharmacogenomic variability, minimising sociodemographic considerations negatively impacting healthcare delivery; making clinical stratifications based on risks of comorbidities; and assessment of genomic cues and clinical patterns to customise therapies, thus improving the disease burden considerably [2]. AI has already been shown to outperform existing methods in its visual diagnostic capacity and ability to integrate and analyse diversified data, thereby becoming better at making distinctive risk predictions and significantly improving individual patient outcomes in the cardinal domain of myocardial infarction [3].
This futuristic mode of healthcare with its exciting prospects inadvertently faces some hurdles the mention of which seems imperative at this stage - for example, AI’s heavy dependence on the quality, applicability, and pertinence of its data to be able to perform the tasks mentioned above; its statistical limitation to make accurate predictions at the individual level; its incapacity as yet to ascertain causation, affecting therapy selection with precision; and the concerns of data safety and privacy [2,4]. In addition, its cost-effectiveness cannot presently be judged as a result of misallocation in the market and systematic biases owing to its novelty in healthcare [5]. Nevertheless, the remarkably accelerating impact of AI in personalising medicine must be acknowledged. In this regard, the upcoming generation of progressive researchers will surely play a profound role in bridging the gap between research and its clinical applications.
Navigating Hyperkalaemia- The A-to-H Clinical Strategy
Authors: Sourabh Sharma  , Sanjay Kalra
Published: December 2024

Hyperkalaemia is a life-threatening dyselectrolytaemiawhich is characterized by elevated serum potassiumlevels. It needs a systematic and overarching approach toeffectively manage a case of hyperkalaemia. We proposea structured A-to-H approach to guide clinicians inmanaging hyperkalaemia, ensuring that no critical aspectis neglected or inadvertently missed. This approachinvolves Analytical accuracy, Background, Clinicalcontext, Diagnosis and drugs, Evaluation, Follow-up,Guidelines adherence, and Health education. With thisarticle, we reiterate the need to properly assess andpromptly manage a case of hyperkalaemia in variousclinical settings, providing detailed explanation of eachcomponent of the ABCDEFGH approach.Keywords: Hyperkalaemia, Potassium, Potassiumbinders, Prevention, Health evaluation.
Sleep Stewardship
Authors: Sanjay Kalra  , Madhur Verma  , Viny Kantroo  , Nitin Kapoor
Published: December 2024

Sleep stewardship is a systematic effort to ensure relaxedand restorative sleep, by optimizing pre-sleep, intra-sleepand post-sleep environment and ambience, in a rationalmanner. It includes not only sleep hygiene andprevention of sleeping pill abuse, but also macro- andmeso-level interventions to improve sleep quality. Theperson living with sleep disorder, their family, members ofsociety, health care professionals, and policy makers: allhave a role to play in sleep stewardship. Sleepstewardship is necessary to improve and maintain humanhealthKeywords: Lemborexant, obstructive sleep apnea,sedatives, sleep, sleep hygiene, tranquilizers, zolpidem.
The Obese Heart
Authors: Sanjay Kalra  , Bhupinder Singh  , Nitin Kapoor
Published: December 2024

Obesity has been described as a chronic metabolicdisease, characterized by excessive adiposity.1 Mostdiscussion about the consequences and complications ofobesity revolves around metabolic dysfunction, such asdysglycaemia, dyslipidaemia and hypertension. There isalso increasing awareness about ectopic adipose tissuedeposition and its deleterious effects.2 Fatty liver, fattypancreas and fatty kidneys are terms that are usedfrequently in clinical descriptions of the disease. In spiteof the strong link between obesity and cardiac ill-health,the term ‘obese heart’ or ‘fatty heart’, however, has notfound traction in medical literature. This may be due tothe complexity of obesity’s impact on the heart.
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Radiação em alimentos: explorando concepções de alunos em contexto amazônico
Authors: Pereira Leal José Fernando , Gomes Mariele da Silva
Published: December 2024

Ciente da importância da radiação e suas aplicações, especificamente da irradiação de alimentos para a região amazônica, devido ao seu papel potencial na conservação e comercialização de produtos locais e regionais, este estudo tem como objetivo avaliar a etapa inicial de um projeto piloto já validado, parte de uma pesquisa de mestrado profissional sobre o ensino de radiação, com foco particular na irradiação de alimentos. A ênfase do estudo recai sobre as percepções iniciais dos estudantes acerca da temática, a partir de um questionário de sondagem. A pesquisa é desenvolvida com estudantes do primeiro ano do Novo Ensino Médio de uma escola pública da rede estadual de Manaus/AM, caracterizando-se como uma pesquisa qualitativa de natureza aplicada. A abordagem metodológica adotada é a Pesquisa-Ação, e, para a coleta de dados, são utilizados instrumentos como questionários. A interpretação dos dados segue a análise descritiva, conforme Gil (2008).Os resultados indicam que os estudantes possuem concepções limitadas e distorcidas sobre a radiação e suas relações, o que os leva a associá-la apenas a situações negativas. Além disso, eles demonstram dificuldade em conectar esses conceitos e suas implicações às suas experiências cotidianas.
Aprendizagem baseada em projetos na abordagem de questões sociocientíficas
Authors: Pereira Miranda Marques Suzane , Martins Milta Mariane da Mata
Published: December 2024

Com fundamentos na Aprendizagem Baseada em Projetos (ABP), junto ao uso e discussão de Questões Sociocientíficas (QSCs) na perspectiva de aperfeiçoar a prática docente no viés da formação crítica e reflexiva. Esta pesquisa teve como objetivo principal o desenvolvimento de uma ação formativa interdisciplinar para professores que atuam nos anos finais do ensino fundamental. O trabalho ancora-se em uma metodologia qualitativa de cunho exploratório por intermédio da pesquisa-ação. Os instrumentos de pesquisa foram dos registros dos encontros formativos por meio da gravação em áudios, cujos dados foram tratados à luz da análise de conteúdo. Após análises dos dados, tivemos como resultado a categoria final, sendo “Benefícios das estratégias desenvolvidas pela ação formativa interdisciplinar com o uso da ABP para a prática do docente”. Ao observar os resultados, entendemos a necessidade de compartilhar ações como essas com outros professores, para tanto, a organização e estrutura desta pesquisa poderá corroborar nos diversos níveis de ensino que tenham interesse em desenvolver projetos interdisciplinares, contribuindo para a formação de cidadãos críticos e reflexivos.
Ensino de estereoquímica baseado em modelagem: inclusão de alunos com a utilização de sementes Amazônicas
Authors: Rodrigues de Carvalho Amauri , Freitas de Souza Ronilson
Published: December 2024

A pesquisa foi desenvolvida para contribuir de forma inclusiva com o ensino e a aprendizagem de estereoquímica, integrando tanto alunos normovisuais quanto aqueles com deficiências visuais no mesmo ambiente de sala de aula. O objetivo central desta pesquisa foi desenvolver competências teóricas, conceituais e contextuais sobre isomeria espacial. Para tanto, foi realizada uma pesquisa qualitativa por meio de estudo de caso, utilizando entrevista semiestruturada e observação participante. Após a aplicação de sequência didática com ensino baseado em modelagem, os dados coletados foram analisados qualitativamente. Os resultados demonstram o potencial da proposta didática, em contribuir para o processo de ensino e aprendizagem relacionados à estereoquímica, favorecidos através das trocas e interações com os materiais adaptados, possibilitando que o aluno com deficiência visual conseguisse compreender os conceitos envolvidos nas representações das moléculas com isomeria. Foi observado um progresso significativo na compreensão dos conceitos relacionados a Estereoisomeria de todos os alunos. Além disso, observou-se uma adequada internalização dos conceitos, evidenciada pelos resultados do pós-teste, que mostraram percentual de acertos superior a 70%. Esta proposta implementada neste estudo avança na promoção de aulas de isomeria mais inclusivas para alunos com deficiência visual.
O Arco de Maguerez como Metodologia para abordagem das Questões Sociocientíficas no Ensino de Ciências:
Authors: Ribeiro Erick Elisson Hosana , Conceição Glaucia Nunes de Souza da
Published: December 2024

Este artigo discute aspectos do desenvolvimento de uma ação formativa  com professores de Ciência Naturais do Ensino Fundamental acerca da abordagem de Questões Sociocientíficas (QSC) utilizando a metodologia da problematização com o Arco de Maguerez (ArM), tendo como objetivo analisar e discutir a percepção de docentes sobre a relevância, possibilidades e desafios desta metodologia para o processo de ensino e aprendizagem. Este tema configura-se como o desdobramento de uma pesquisa no contexto da ação formativa, caracterizando-se como uma abordagem qualitativa, com procedimentos da pesquisa-ação, tendo como instrumento de coleta de informações um questionário e como técnica de análise a Análise Textual Discursiva (ATD). A discussão aborda as colocações dos professores através das respostas obtidas a respeito da experiência vivenciada com esta metodologia durante este processo de formação continuada e evidencia os desafios e potencialidades inerentes a este processo, associado à abordagem das Questões Sociocientíficas. A partir dos resultados alcançados, concluiu-se que na visão dos professores de Ciências participantes, a metodologia do Arco de Maguerez é de compreensão acessível, possui viabilidade para ser empregada em contextos do ensino fundamental, e apresenta grandes possibilidades para o desenvolvimento do pensamento crítico, da capacidade de resolução de problemas, e da construção de conceitos no ensino de ciências.
Offender and Victim as Elements of Crime: a Criminological Analysis
Authors: Gorshenkov Andrey G. , Gorshenkov Gennady G. , Gorshenkov Gennady N.
Published: December 2024

The article analyzes the long-standing idea of studying the relations that develop, develop or arise situationally between the criminal and the victim, causing their interaction, the energy of which enters the system of determination of the crime, playing a dominant role in it . The main approaches and methods of studying this problem are considered as the leading elements of research technology, including the system-synergetic approach and criminological-analytical analysis . The solution of the main task of the study is being implemented, which consists in the optimization of criminological thinking, methodological understanding of the subject of research through analytical analysis and the use of its possibilities for a detailed consideration of the main subjective qualitative elements integrated into the system of criminogenic and victimogenic determination of crime . The author suggests the need for a criminological study of non-victim behavior in order to use the acquired empirical knowledge in the development of specific measures of multilateral victimological prevention .
Crime, its Victim and Morality
Authors: Shienok Vladimir P. , Rezyuk Vadim I.
Published: December 2024

The article examines the crime, its victim and morality. In their analysis, the authors proceed from the fact that criminology, criminal law, and other legal sciences must turn to the study of their main object - man as a system consisting of spiritual and material sides - which is a necessary condition for ensuring harmony between normative regulators of human behavior and their internal attitudes, as well as the norms of public morality. The most effective means of regulatory regulation are those that correlate with the moral attitudes of a person and society. The risks of activities aimed at changing the moral values of society in favor of the temporary situation are noted, and the need to take into account the versatility of the moral and legal assessment of the crime, its victim and the criminal is justified.
Victimological Characteristics of Crimes Associated with Incitement to Suicide
Authors: Talan Maria V. , Shalagin Anton E. , Idiyatullov Almaz D.
Published: December 2024

The article examines the victimological aspects of crimes involving incitement to suicide .During the study, 251 court decisions in criminal cases on incitement to suicide, inducement to commit suicide or assistance in it, organization of activities aimed at inducing suicide from 62 constituent entities of the Russian Federation for the years 1998-2023 were studied .Most often, victims of such crimes are found in the family, domestic and professional spheres, when crimes are committed using IT technologies . During the study, attention was paid to biophysiological (gender, age, health status, pathological desires, behavioral deviations), socio-demographic (education, marital status, presence of children, professional affiliation) and moral and psychological characteristics (views, beliefs, value orientations, volitional and intellectual personality traits, life attitudes) characterizing the victim . Victimologically significant features of the behavior of the victim of such crimes (place, season of the year, time of suicide, methods, means and methods of its implementation, the presence of suicide notes) are noted . Individual illegal actions that are in a cause-and-effect relationship with the suicidal behavior of the victim are analyzed . Signs indicating the presence of intentions and attempts to commit suicide have been identified . Particular attention is paid to the patterns of victim behavior and the identification of determining factors . The signs of victimization of crime victims are considered .
Social Ideas of Student Youth about Violence in Intimate and Personal Relationships (on the example of students of KSU named after K. E. Tsiolkovsky)
Authors: Sabitova Irina S.
Published: December 2024

Identifying the causes of violence in intimate-personal relationships is one of the important tasks in the field of security psychology, which has not yet been fully resolved. In modern research, the study of young people’s social perceptions of violence in intimate-personal relationships is crucial for the development of methods to prevent its occurrence . Victimhood in behavior is often determined by inadequate perceptions of “red lines” in relationships and attitudes to their violation. The study of the peculiarities of social perceptions presented in this article on the example of students of Kaluga State University named after K. E. Tsiolkovsky allowed to reveal the specifics of perception, formed images, associations, meanings, ideas, values, attitudes, on the basis of which students explain violence in relationships. The obtained results allowed us to come to the conclusion that the studied consider this problem to be actual and widespread all over the world, perceive violence in intimate-personal relations as culturally and historically conditioned destructive actions of psychological and physical nature, based on inequality, use of force and power, pressure and control, leading to harmful consequences of psychological and physical nature and having no legal solution.
Human Trafficking: Risk Profile of Victims and Traffickers and the Scope of Forensic Victimology
Authors: Gopalan Rejani Thudalikunnil
Published: December 2024

Human trafficking is a growing problem across the world and the actual estimation of this crime is not yet done due to methodological issues and the underreporting of cases. The victim’s uncooperativeness in many cases or trying to conceal the identity of the victim due to many sociocultural factors poses a barrier to understanding the profile of the victims and traffickers. This article attempts to create a risk profile of victims and human traffickers based on available literature and various factors like gender, children, profession, migration, socioeconomic and cultural factors and political conditions were emphasized . In addition to this, the article focused on the importance of Forensic victimology in the area of human trafficking. The author emphasized that this crime is as important and complicated as sexual abuse/assault and tressed the need for more research in the field of forensic victimology especially on victims and traffickers to understand the dynamics of human trafficking which leads to better profiling, deepened knowledge of entrapment strategies and relationships between victims and traffickers that will help the criminal justice system as well as to make strategies for prevention and interventions . This crime is as important and complicated as sexual abuse/assault.
Economic assessment of the effectiveness of the use of artifitial intelligence in the service sector
Authors:   Ufa State Petroleum Technical University, Matveeva Lyubov D. , Iraeva Nadezhda G. ,   Ufa State Petroleum Technical University, Raimova Adel R. ,   Ufa State Petroleum Technical University
Published: December 2024

This article is devoted to the analysis of the impact of the introduction of artificial intelligence (AI) technologies on the economic performance of service enterprises. In the face of increasing competition and ever-increasing demands on the quality of service, the use of AI is becoming a strategic factor in improving efficiency and competitiveness. The study aims not only to assess the economic benefits of using AI in various service areas, but also to identify key factors affecting the effectiveness of implementation, as well as to develop recommendations for optimizing investment decisions in this area. The theoretical value of the work lies in the development and application of a comprehensive methodology for evaluating the economic efficiency of AI solutions in the service industry. The results obtained can be used to substantiate investment projects, plan a strategy for the development of service enterprises and increase their competitive position in the market.
Correlation analysis of the dependence of oil refining on oil production
Authors:   Bashkir Institute of Social Technologies (branch) of the Academy of Labor and Social Relations, Gilmutdinov Rif Z. , Melnik Lyubov Yu. ,   Ufa State Petroleum Technological University, Tukhvatullina Laysan R. ,   Ufa State Petroleum Technological University
Published: December 2024

The aim of the work is to identify the statistical relationship between oil production and its refining and to determine the best way to study this relationship. Although it is economically clear that such an influence is mutual, in this case the exact degree of dependence is important, and therefore what equation connects the amount of oil refining and the size of its production. Linear and parabolic regression algorithms are used as research methods. The regression equation allows you to find out what the effect of the main factors on the dependent variable would be if other factors remain unchanged and random elements are excluded. Further, using the regression equation, interpolation and extrapolation methods can reproduce the values of the dependent variable both within the interval of specified values of independent variables and outside the specified interval. Data for 2007–2018 are taken deliberately. During this period, the economy developed without sharp economic, political and other surges, which provides more opportunities to trace the dependence of oil production on the volume of refining.