bluuebunny/crossref_metadata_2025 huggingface dataset:
Patrones de práctica clínica en la enfermedad de Graves en Colombia
Authors: Perdomo-Par Diego Armando , Builes-Montaño Carlos Esteban , Donado-Gomez Jorge Hernando
Published: February 2022

Contexto: la principal causa de hipertiroidismo en el mundo es la enfermedad de Graves, cuya incidencia viene en aumento. En Colombia se asume una epidemiología de la enfermedad similar a la de otros países con la suficiencia de yodo y en otras latitudes se han reportado diferencias entre los especialistas encargados del diagnóstico y el tratamiento de la enfermedad de Graves.

Objetivo: se realizó una encuesta nacional basada en casos clínicos hipotéticos para conocer las conductas de los endocrinólogos colombianos en el tratamiento de la enfermedad de Graves.

Metodología: la encuesta estuvo basada en un servicio de manejo en la web y fue aplicada a médicos especialistas en Endocrinología adscritos a la Asociación Colombiana de Endocrinología, Diabetes y Metabolismo (ACE). El porcentaje de respuestas se obtuvo individualmente para cada pregunta usando el número de los participantes que la respondieron en el denominador.

Resultados: de los endocrinólogos contactados, el 36?% respondió la encuesta. Sobre esta población y al momento del diagnóstico, la mayoría repetiría la medición de TSH y T4 libre (83?% y 81?% respectivamente), el 61?% solicitaría una gammagrafía tiroidea con tecnecio y la mayoría de los encuestados utilizarían beta bloqueadores asociados a antitiroideos como una primera línea de tratamiento y, en todos los casos, el antitiroideo seleccionado fue el metimazol. Una proporción importante de los encuestados haría seguimiento con hemograma o pruebas de función hepática aparte de las pruebas de función tiroidea y una cantidad no despreciable de pacientes serían tratados por parte de su médico con antitiroideos por un periodo inferior a un año.

Conclusiones: este estudio sugiere el estado actual del tratamiento de la enfermedad de Graves en Colombia por parte de los especialistas en Endocrinología, el cual en la mayoría de los aspectos sigue las recomendaciones de las guías de tratamiento publicadas en otros países. Algunas conductas distan de las recomendaciones basadas en la evidencia y esto pudiera exponer a los pacientes con enfermedad de Graves a riesgos innecesarios o imponer costos adicionales. Por último, algunas de las prácticas reportadas están influenciadas por condiciones del sistema de salud colombiano o por disponibilidad, lo cual sugiere que deberían desarrollarse guías locales adaptadas a estas peculiaridades.
Dilâlah Makna Rûh Dalam Penafsiran Quraish Shihab
Authors: Pane Ismail
Published: February 2022

Tulisan ini berjudul “Dilâlah Makna Rûh Dalam Penafsiran Quraish Shihab, tujuannya untuk memperjelas makna kata Rûh. Walaupun Allah telah menurunkan al-Qur’ân dengan bahasa Arab yang jelas, tetapi belum semua umat Islam paham dan mengerti makna kata-kata yang terdapat dalam al-Qur’ân. Khususnya mengenai makna dan penafsiran kata Rûh. Maka yang menjadi pokok penelitian ini adalah menguraikan bagaimana makna dan penafsiran kata Rûh yang terdapat dalam al-Qur’ân, serta bagaimana penafsiran kata Rûh menurut Muhammad Quraish Shihab. Pada konteks apa saja Rûh itu dimaknai Jiwa (potensi hidup manusia), Jibrîl, maupun al-Qur’ân, dan apakah ada makna lain selain yang telah disebutkan di atas. Adapun kesimpulannya adalah bahwa di dalam al-Qur’ân makna Rûh terdapat 21 kali dalam 20 ayat dalam 18 surat pengulangan. Dari penafsiran yang dilakukan Muhammad Quraish Shihab dalam menafsirkan Dilâlah makna Rûh dalam al-Qur’ân, dimana secara umum bahwa memaknai kata Rûh mengandung makna sesuatu yang membuat makhluk bisa hidup (Jiwa), dan juga bermakna malaikat Jibrîl ataupun al-Qur’ân, bahkan pertolongan dari Allah. Namun, dalam menafsirkan makna Rûh dalam al-Qur’ân tidak memberikan sebuah pendapat atau pemikirannya secara eksplisit tentang makna Rûh, hanya memberikan pemaparan pendapat ulama lain. Selanjutnya, Muhammad Quraish Shihab dalam menafsirkan makna ayat mengenai kata Rûh menggunakan hadis Rasulullah saw. dan perkataan sahabat, dan jarang menggunakan atau pun mengutip perkataan ulama tafsîr lainnya.
Enfoque radiológico de la enfermedad de Forestier-Rotes-Querol. Presentación de caso
Authors: Cárcamo Mejía Sandra María , Pavón Núñez Digna Sarahí , Bu Figueroa Mildred Jeaneth
Published: February 2022

Se presenta el caso de una paciente femenina de 64 años de edad, con comorbilidades asociadas,  quien acude al Instituto Hondureño de Seguridad Social por dolor y rigidez cervical de evolución  crónica. En estudios de resonancia magnética se observa protrusión ósea con formación de puentes  anteriores a los cuerpos vertebrales, que concuerda con las alteraciones halladas en tomografía  y radiografía cervical. La hiperostosis esquelética difusa idiopática, o enfermedad de Forestier[1]Rotes-Querol, es una patología de la columna poco reconocida que puede cursar asintomática  y desapercibida, pero ante dolor cervical la tomografía de columna es el método de estudio  inicial e ideal para la valoración ósea en caso de patologías osificantes y degenerativas, que al  complementar con resonancia magnética ayuda a realizar un diagnóstico preciso, para decidir  entre un tratamiento quirúrgico o un manejo conservador.
Honeybees diversity, pollination, entrepreneurship and beekeeping scenario in NEH region of India
Authors: Haldhar SM , Nidhi CN , Singh KI , Devi AS
Published: February 2022

The north-eastern region of India with diverse forage resources encompasses great potential in beekeeping. The honeybee species existing in the north-eastern hill region are Apis dorsata, A. florea, A. cerana himalaya, A. mellifera, A. laboriosa and Trigona iridepennis. Modern agriculture has come to depend greatly on the bees to fulfill its pollination needs. Pollen analysis from North-eastern hill region revealed that the dominant sporomorphs were Brassica sp., Solamun sp., Helianthus sp., Wendlandia sp., Clematis sp., Adhatoda sp. and Mussaenda sp. Bee flora was identified as 107 plants from North-eastern region of India. Different types of entrepreneurship can be developed through beekeeping like honey bees rearing, sale of honey bees colonies, consultancy to farmers for honey bee rearing, processing of honey at large scale and marketing of honey products. Available information on honeybee’s diversity, pollination, entrepreneurship and beekeeping scenario for sustainable agriculture of north-eastern hill region are reviewed and discussed.
Polyploid rootstocks in citrus for mitigation of biotic and abiotic stresses: A review
Authors: Gora JS , Ram Chet , Poonia PK , Choudhary M , Haldhar SM
Published: February 2022

Citrus is growing commercially worldwide for its nutritious value and economical aspects. By 2030, citrus fruit demand will be more around 50 percent as human diet. However, the environmental stresses are badly affected citrus production and productivity as well as fruit quality. These factors are reduced citrus production by 30-60 per cent in traditional citrus growing area in the world due to the lack of suitable rootstocks. The polyploidy rootstocks can play pivotal role to mitigate the environmental impacts and sustainability in citriculture for vigor and fruit quality. Polyploid citrus rootstocks have great importance in crop improvement programmes due to their attributes to the higher vigor, dwarfism, resistant to biotic and abiotic stresses when compared to their diploid counterparts. They exhibit deep and thick root system with less number of secondary roots, more ABA synthesis, leathery and thick leaves, bigger sized stomata with less density, high antioxidant system etc. In the present paper, an attempt has been made to elucidate and discuss the importance of polyploidy rootstocks developed so far for various horticultural traits in citrus.
New therapeutic opportunities for Alzheimer disease
Authors: Jang Jae-Won
Published: February 2022

The number of Alzheimer disease (AD) is increasing worldwide and it is still the most common cause of dementia. However, there are limited treatment option with just symptomatic medications. Therefore new disease modifying drugs were in great need for many years for AD treatment. Recently, aducanumab which is beta amyloid targeted immunotherapy, has been approved by the US Food and Drug Administration for the treatment of AD. Although there are many questions to be answered, this would be the landmark for AD drug that attempt to treat a neurodegenerative disease rather than just symptoms. In this review, I would like to discuss the current development status of dementia treatment, its limitations, and the future opportunity.
Biocontrol Activity of Aspergillus terreus ANU-301 against Two Distinct Plant Diseases, Tomato Fusarium Wilt and Potato Soft Rot
Authors: Choi Hyong Woo , Ahsan S. M.
Published: February 2022

To screen antagonistic fungi against plant pathogens, dual culture assay (DCA) and culture filtrate assay (CFA) were performed with unknown soil-born fungi. Among the different fungi isolated and screened from the soil, fungal isolate ANU-301 successfully inhibited growth of different plant pathogenic fungi, Colletotrichum acutatum, Alternaria alternata, and Fusarium oxysporum, in DCA and CFA. Morphological characteristics and rDNA internal transcribed spacer sequence analysis identified ANU-301 as Aspergillus terreus. Inoculation of tomato plants with Fusarium oxysporum f. sp. lycopersici (FOL) induced severe wilting symptom; however, co-inoculation with ANU-301 significantly enhanced resistance of tomato plants against FOL. In addition, culture filtrate (CF) of ANU-301 not only showed bacterial growth inhibition activity against Dickeya chrysanthemi (Dc), but also demonstrated protective effect in potato tuber against soft rot disease. Gas chromatography-tandem mass spectrometry analysis of CF of ANU-301 identified 2,4-bis(1-methyl-1-phenylethyl)-phenol (MPP) as the most abundant compound. MPP inhibited growth of Dc, but not of FOL, in a dose-dependent manner, and protected potato tuber from the soft rot disease induced by Dc. In conclusion, Aspergillus terreus ANU-301 could be used and further tested as a potential biological control agent.
Sistematización de experiencias en el curso de Técnicas e Instrumentos para la Orientación Vocacional de la Carrera de Orientación de la UNA
Authors: Vargas-Hernández Evelyn
Published: February 2022

Este documento tiene como finalidad compartir la sistematización efectuada al proceso de organización, desarrollo y ejecución del curso Técnicas e Instrumentos para la Orientación Vocacional (TIOV), impartido en el III nivel de la carrera de Orientación de la Universidad Nacional de Costa Rica, durante el periodo comprendido entre el 11 de febrero y el 20 de junio del 2019. Los objetivos propuestos fueron: identificar las diversas etapas teóricas y prácticas de las estrategias de aprendizaje aplicadas en el curso y promover acciones de mejora a los cursos de Orientación Vocacional I, II y III, a partir de las experiencias obtenidas en el desarrollo de las estrategias metodológicas del curso TIOV. Para conseguir dichos objetivos, se aplicó el proceso metodológico definido por el programa del Centro de Estudios y Publicaciones Alforja, bajo la guía del director general, Dr. Oscar Jara Holliday. En cuanto a los materiales por sistematizar, se hizo revisión del informe final del curso, registros identificados en el aula virtual, archivos de la docente con los contenidos y seguimiento de forma semanal, así como el cronograma y el programa del curso. Además, se aplicó un instrumento para recolección de información, acerca de algunas vivencias y opiniones de cinco estudiantes que estuvieron en el proceso, y a la profesora que da el mismo curso a otro grupo. Por último, se recolectaron fotografías de los eventos, materiales físicos y digitales elaborados por los estudiantes. A partir de esto, se obtuvieron las conclusiones y recomendaciones de mejora descritas en este documento.
Pemulihan Konsep Diri dalam Penyembuhan Luka Batin
Authors: Maria Agnes
Published: February 2022

Setiap orang tidak dapat menghindar dari penderitaan. Penderitaan itu bisa berupa luka, baik besar maupun kecil, baik luka fisik maupun jiwa. Luka jiwa atau yang biasa disebut luka batin dapat terjadi melalui banyak peristiwa, antara lain peristiwa traumatis, baik dari lingkungan keluarga maupun dari lingkungan sekitarnya. Perasaan bersalah juga dapat menjadi penyebab luka batin, juga karena adanya penolakan. Luka batin berdampak buruk bagi seseorang baik secara sosiologis, psikologis, fisiologis, dan teologis. Berdasarkan metode kualitatif, artikel ini menjelaskan pemulihan konsep diri dalam penyembuhan luka batin seseorang. Sebagai hasil dari penelitian ini, luka batin dapat disembuhkan dengan pemulihan konsep diri seseorang. Konsep diri harus dipulihkan sesuai kebenaran firman Tuhan yang menyadarkan manusia betapa besarnya kasih Tuhan kepadanya.
Lithological and facial features of organogenic structures of the second carbonate stratum of the eastern flang of the Pre-Caspian depression on Zharkamys uplift
Authors: Каn Andrei N. , Akhmetshina Lemuza Z.
Published: February 2022

The Peri-Caspian Basin is the major oil and gas basin in Kazakhstan. It contains huge hydrocarbon reserves within pre-salt carbonate deposits.
Numerous oil and gas-condensate fields, associated with the pre-salt carbonate complexes had been discovered in the Eastern part of the Peri-Caspian Depression.
This work aims at the study of the second carbonate sequence (CS-II) of the Late Visean – Early Moskovian ages of the Eastern edge of the Peri-Caspian Depression. The formation of the Eastern edge of the Peri-Caspian Depression took place in the zone of the junction of the East European craton and folded structures of the Urals. These conditions predetermined the complexity of the sedimentation processes, variety of lithological types of rocks, and the diagenesis processes with the formation of high heterogeneity of the reservoirs.
The CS-II will retain the leading role as the main reservoir of hydrocarbons and it has the further potential for oil exploration in the region for two to three decades. It is confirmed by the discovery of the large oil and gas-condensate fields in the CS-II, such as Zhanazhol, Urikhtau, Kozhasai, Alibekmola, etc.
أبعاد التنظيم التشريعي للعملات الإلكترونية والافتراضية في مصر وفرنسا
Authors: محمد عبد اللطيف محمد
Published: February 2022

لا يتوقف تطور التكنولوجيا الرقمية عند حد، فنراه قد تدخل في مجالات عديدة، ومنها المجال المالي، وأثمر تطبيقها عن ظهور طائفة جديدة من العملات التي اتخذت نوعين أساسيين هما: العملات الإليكترونية، والعملات الافتراضية أو المشفَّرة. وقد انتشر استخدام هذه العملات كثيرًا حتى من قبل أن يتدخل القانون لتنظيمها الأمر الذي يثير التساؤل عن موقف القانون من استخدامها.  
وإذا كان القانون لا يقف مانعًا من تطبيق تطورات التكنولوجيا ويضع فقط مجرد إطار لتنظيم تطبيقها؛ فإن موقفه قد تغير من العملات الإلكترونية والافتراضية بالنظر لوجود مبادئ دستورية صارمة تحول دون الاعتراف بها بوصفها عملات قانونية. وقد تجلى هذا الرفض بشكل قاطع بالنسبة للعملات الافتراضية في معظم بلدان العالم، وسوف نعرض بطبيعة الحال أهم الأسباب القانونية لهذا الرفض. 
أما بالنسبة للعملات الإلكترونية فقد نظمها المشرع في عدد من الدول ومنها مصر وفرنسا ليس بوصفها عملات بالمعنى القانوني المحدد، ولكن بوصفها أدوات للدفع. وجاء التنظيم التشريع هنا واسعًا يغطي عددًا كبيرًا من النقط مثل المؤسسات المعنية وعملية الإصدار وحقوق الحائزين للعملاء.  
نقترح في هذا البحث دراسة التنظيم التشريعي للعملات الإلكترونية والعملات الافتراضية، وموقف القانون والقضاء من هذه العملات في كل من مصر وفرنسا وأيضًا في قانون الاتحاد الأوروبي. ومن الملاحظ أن التنظيم التشريعي للعملات الإلكترونية في القانون الفرنسي وقانون الاتحاد الأوروبي بدأ مبكرًا بدءًا من التسعينيات من القرن الماضي بينما التدخل التشريعي في القانون المصري لم يبدأ إلا حديثًا في العام 2020. 
وسوف نعرض لهذه الدراسة من خلال بحث موقف الدستور من العملات الإلكترونية والافتراضية، وموقف التشريع من تكييف هذه العملات، وأخيرًا التنظيم التشريعي للعملات الإلكترونية والافتراضية.
Prediksi Kebutuhan Tempat Tidur Pasien COVID-19 di Rumah Sakit Umum Daerah dr.Wahidin Sudiro Husodo Kota Mojokerto (Juni 2021-Juli 2022)
Authors: Sidjabat Forman
Published: February 2022

Pandemi COVID-19 berdampak besar pada banyak rumah sakit mulai Maret 2020. Secara global, rumah sakit perlu menyiapkan ruangan dengan kapasitas yang memadai sesuai kebutuhan pasien COVID-19. Salah satu indikator untuk menilai peningkatan permintaan pelayanan rumah sakit pada masa pandemi dapat dilihat dari nilai Bed Occupancy Rate. Nilai BOR RSUD dr. Wahidin Sudirohusodo pada periode April 2020-Mei 2021 berada di bawah standar. Penelitian ini bertujuan untuk memprediksi kebutuhan tempat tidur pasien Covid-19 di RSUD dr. Wahidin Sudiro Husodo Mojokerto untuk periode Juni 2021-Juli 2022. Penelitian ini menggunakan penelitian deskriptif dengan pendekatan retrospektif. Subyek penelitian adalah data rekapitulasi pasien Covid-19 menggunakan teknik observasi dengan mencatat jumlah tempat tidur dan jumlah hari rawat inap pasien Covid-19 periode April 2020-Mei 2021. Analisis data dilakukan dengan menggunakan fungsi linear least squares dan diprediksi menggunakan nilai BOR 60%, 70% dan 80%. Kebutuhan tempat tidur pasien Covid-19 di RSUD dr. Wahidin Sudiro Husodo Mojokerto periode Juni 2021–Juli 2022 (BOR 60%: 40-65 tempat tidur, 70%: 34-56 tempat tidur, 85%: 28-46 tempat tidur) di bawah jumlah tempat tidur yang telah dialokasikan oleh rumah sakit untuk pengiriman layanan COVID 19 (16-81 tempat tidur). Kelebihan tempat tidur untuk merawat pasien COVID-19 dapat menjadi dasar bagi manajemen rumah sakit untuk meninjau pengadaan dan penempatan tempat tidur yang sesuai.
Perancangan Sistem Rekomendasi Apotek di Wilayah Kota Singaraja
Authors: Komang Ananta Wijaya
Published: February 2022

Singaraja merupakan salah satu kota yang terletak di wilayah Bali Utara. Wilayah Kota Singaraja khususnya banyak terdapat apotek-apotek yang berbeda-beda. Sangat membingungkan jika ingin mencari apotek terdekat dari tempat tinggal, dan banyak masyarakat juga tidak tahu alamat apotek tersebut serta kelengkapan obat dan fasilitas kesehatan yang tersedia. Oleh sebab itu, maka dengan sistem LBS yang memanfaatkan teknologi GPS, dengan mudah orang-orang atau pengguna dapat mengetahui posisinya dan tempat-tempat tertentu, dimana tempat yang dibahas pada penelitian ini adalah Apotek di Wilayaha Kota Singaraja. Apotek merupakan sebuah tempat atau sarana yang digunakan untuk melakukan pelayanan kesehatan, apotek juga digunakan sebagai tempat meramu, menyediakan dan menyalurkan obat-obatan baik eceran atau dengan resep dokter. Rancangan sistem ini akan bekerja dengan menggunakan metode kolaboratif. Selain metode tersebut, sistem ini menggunakan Location-Based Service (LBS) yang memanfaatkan teknologi Global Positioning System (GPS) dalam pengaplikasiannya, maka pengguna dapat mengetahui posisinya serta pengguna dapat menentukan dan mencari apotek baik itu tempat yang jauh maupun dekat. Sistem ini berjalan pada perangkat mobile android. Dengan adanya rancangan sistem ini, maka diharapkan kedepannya dapat mempermudah masyarakat dalam pencarian apotek terdekat dari lokasinya berada, kelengkapan fasilitas dan sarana kesehatan yang disediakan.
To whom should I be kind? A randomized trial about kindness for strong and weak social ties on mental wellbeing and its specific mechanisms of change
Authors: Wieners Leonie , Van Zyl Llewellyn Ellardus , Radstaak Mirjam , Schotanus-Dijkstra Marijke
Published: February 2022

The current study examines the role of social ties in performing kind acts to enhance university students’ wellbeing. Due to facing multifaceted challenges, university students form a group that is particularly vulnerable in terms of their mental health. Interventions harnessing prosocial behaviour have the potential to increase students’ wellbeing, strengthen personal competencies, and broaden social networks. The first aim of the trial (N = 222) was to explore whether a 4-week acts-of-kindness intervention targeting either (1) strong social ties, (2) weak social ties or (3) unspecified receivers (treatment-as-usual) differ in their impact on students’ mental wellbeing, positive relations, depressive symptoms, anxiety, and perceived stress. The second aim was to examine whether kindness for strong versus weak social ties have different underlying working mechanisms (i.e., positive emotions versus self-esteem) and who benefits most from these instructions (i.e., those with high or low levels of self-esteem and positive relations). Results demonstrated that the most significant improvements in mental wellbeing were found in the kindness for strong social ties condition compared to the other conditions. No mediation effects of positive emotions and self-esteem were found. Moderation analyses revealed that participants who performed kind acts for weak social ties reported significantly less positive effects on mental wellbeing, but only when their levels of self-esteem at baseline were medium or high. Independent of group allocation, participants’ mental wellbeing increased throughout the intervention, but so did the experience of depressive symptoms, anxiety, and perceived stress. More research is needed to examine the timing of kindness interventions and investigate how they can improve mental wellbeing and psychological distress in acute phases of academic stress in university students.
Pengaruh Budaya Organisasi Terhadap Kinerja Pegawai BPJS Ketenagakerjaan
Authors: Abdi
Published: February 2022

Potensi setiap sumber daya manusia yang ada dalam perusahaan harus dapat dimanfaatkan dengan sebaik-baiknya sehingga mampu memberikanoutput optimal. Oleh karena itu, perusahaan juga dituntut untuk mampu mengidentifikasi hal-hal apa saja yang menjadi kendala atau permasalahan didalam menjalankan kegiatan dan aktivitas ekonomi, termasuk masalah kinerja pegawainya dimana setiap perusahaan memiliki budaya organisasi. makapenulis merumuskan masalah sebagai berikut “Bagaimana pengaruh budaya organisasi terhadap kinerja pegawai BPJS Ketenagakerjaan CabangBinjai?”Pendekatan dalam penelitian ini menggunakan metode kuantitatif deskriptif. Teknik analisis data berupa teknik analisis deskriptif hasil daripenelitiannya yaitu Budaya organisasi berpengaruh positif dan signifikan terhadap kinerja pegawai di BPJS Ketenagakerjaan Cabang Binjai denganthitung > ttabel (2.884 > 2.030) dan nilai koefisien regresi sebesar 0.404 atau 40.4%. Budaya organisasi berpengaruh signifikan terhadap variabel kinerjapegawai di BPJS Ketenagakerjaan Cabang Binjai
Analisis Kinerja Keuangan Laporan Realisasi Anggaran Pendapatan dan Belanja Daerah Kota Bogor Tahun 2014-2019
Authors: Silvianingsih Rika , Rani Utpala
Published: February 2022

The purpose of this study was to determine the financial performance of Bogor City from 2014 to 2019 based on the calculation of five ratios, namely: independence ratio, ratio, fiscal degree, regional financial dependence ratio, effectiveness ratio of local revenue, and regional financial efficiency ratio. This type of research is carried out by quantitative research and the data used are secondary data taken from ppid.kotabogor.go.id. The results of this study indicate that the financial performance of the city of Bogor is fine when measured by the Regional Financial Independence Ratio, Effectiveness Ratio of Regional Original Income, and the Degree Ratio of Fiscal Decentralization, but the Regional Financial Dependency Ratio does not optimize income from other sectors, resulting the level of dependence on funds transfers are still very high and the Efficiency Ratio is less efficient because the regional expenditure is greater than the regional income received.
An Inequality of Simpson's type Via Quasi-Convex Mappings with Applications
Authors: Alomari Mohammad
Published: February 2022

In this paper, an inequality of Simpson type for quasi-convex mappings is proved. The constant in the classical Simpson's inequality is improved. Furthermore, the obtained bounds can be (much) better than some recent obtained bounds. Application to Simpson's quadrature rule is also given.
Computing the Steady state Dynamics: The Chemical Graphs of Complex Reaction
Authors: Ali Bilal , Jubair Sidra
Published: February 2022

In a thermodynamically isolated system, in order to obtain numerical approximations of the complex models, different model reduction techniques are applied to reduce the complex chemical reactions from high dimensional to low dimensional manifolds. These techniques not only reduce the system but also provide the complete description of reaction kinetics. These techniques include Quasi Steady State Approximations, Partial Equilibrium Technique, Intrinsic Low Dimensional Manifold Method, etc. Among all these techniques, Spectral Quasi Equilibrium Manifold Method is one of the most convenient way to find the initial approximations of slow invariant manifolds. Initial invariant grids completely describe the slow invariant manifolds which are obtained from the dissipative system. This method is applicable for high dimensional complex chemical reactions.
PENGARUH LATIHAN SPEED DAN AGILITY TERHADAP PENINGKATAN KECEPATAN TENDANGAN SAMPING PADA ATLET PENCAK SILAT PUTRA PERGURUAN PERSILATAN SALAM TAHUN 2020
Authors: Yakin Riski Berkat , Hasibuan Muhammad Nustan
Published: February 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh latihan speed dan agility terhadap peningkatan kecepatan tendangan samping pada atlet pencak silat putra perguruan persilatan salam. Metode yang digunakan adalah metode eksperimen dengan desain pre-test dan post-test one group desain. Populasi dalam penelitian ini sebanyak 25 0rang, dan sampel yang diambil berjumlah 7 orang  diambil dengan cara sampeling purposive. Penelitian ini dilakukan 18 kali pertemuan sebanyak 3 kali dalam satu minggu selama 6 minggu. Hasil analisis data menunjukkan ada peningkatan kemampuan kecepatan tendangan samping setelah mendapatkan perlakuan. Teknik analisis data menggunakan uji-t, dengan hasil hipotesis pada latihan speed dan agility terhadap peningkatan kecepatan tendangan samping diperoleh t-hitung= 2,54 serta t-tabel = 2,44 dengan α = 0,05 (t-hitung > t-tabel) berarti H0 ditolak dan Ha diterima. Kesimpulan dari latihan Speed dan agility yaitu terdapat pengaruh latihan Speed dan agility terhadap peningkatan kecepatan tendangan samping pada atlet pencak silat putra perguruan persilatan salam tahun 2020.
PENGEMBANGAN VARIASI LATIHAN TEKNIK DASAR PENJAGA GAWANG HOCKEY TAHUN 2020
Authors: Bangun Feristiwa Hadinata Putra , Ibrahim
Published: February 2022

Penelitian pengembangan ini bertujuan untuk mengembangkan variasi latihan penjaga gawang hockey tahun 2020. Metode penelitian dan pengembangan research and development (R&D) ini di sertai dengan pendekatan kualitatif. instrumen yang digunakan dalam penelitian dan pengembangan ini adalah a. Telaah para pakar/ ahli. Hasil pengembangan dapat disimpulkan bahwa: Diperlukan variasi latihan penjaga gawang hockey yang dikembangkan agar dapat meningkatkan kemampuan teknik penjaga gawangatlet. Dengan variasi latihan yang dikembangkan atlet yang berlatih lebih efektif dan lebih efesien. Dengan variasi latihan penjaga gawang yang dikembangkan atlet lebih termotivasi dalam suasana kompetitif. Dengan pengembangan variasi latihan penjaga gawang ini atlet lebih termotivasi untuk mendapatkan variasi-variasi baru khususnya dalam penjaga gawang hockey tahun 2020. dengan adanya pengembangan  variasi-variasi latihan penjaga gawangini diharapkan dapat mengembangkan variasi-variasi penjaga gawang hockeydalam berlatih atau bertanding. Dengan hasil penelitian ini diharapkan atlet harus lebih kreatif dan inovatif dalam memainkan variasi-variasi latihan penjaga gawang dalam permainan hockey yang lain.
PERLINDUNGAN HUKUM TERHADAP KONSUMEN DALAM PELAYANAN AIR MINUM OLEH PERUSAHAAN DAERAH AIR MINUM GIRI TIRTA KABUPATEN GRESIK
Authors: Nasichin Moch. , Hidayati Nurul
Published: February 2022

Masyarakat Kabupaten Gresik selaku pelanggan air minum seringkali hak-haknya tidak terpenuhi oleh PDAM Giri Tirta Kabupaten Gresik, namun pelanggan tetap dituntut membayar tagihan air dan dikenai sanksi apabila terlambat membayar. Penelitian ini bertujuan mengetahui bentuk perlindungan hukum terhadap konsumen dalam pelayanan air minum PDAM Giri Tirta dan mekanisme penyelesaian sengketa terhadap kelalaian pelayanan PDAM Giri Tirta. Penelitian ini menggunakan metode penelitian hukum normatif dengan meneliti peraturan perundangan khususnya UUPK dan bahan pustaka lain terkait perlindungan konsumen air minum. Hasil penelitian menunjukkan bahwa belum ada bentuk perlindungan hukum terhadap pelanggan PDAM Giri Tirta yang mengacu pada UUPK. Penyelesaian sengketa konsumen selama ini dilakukan secara damai antara pelanggan dengan PDAM Giri Tirta. Namun apabila pelanggan belum merasa puas atas penyelesaian sengketa oleh PDAM Giri Tirta, pelanggan dapat menyelesaikan sengketanya melalui lembaga pengadilan atau badan penyelesaian sengketa konsumen (BPSK).Ã‚Â Kata Kunci: Air Minum, Konsumen, PDAM, UUPK.
ASPEK YURIDIS HAK ASUH ANAK AKIBAT PERCERAIAN ORANG TUA BERDASARKAN UNDANG-UNDANG PERKAWINAN DAN UNDANG-UNDANG PERLINDUNGAN ANAK (StudiKasusPerkara No. 098/Pdt.G/2017/PA.Gs)
Authors: Arkisman Arkisman , Hadi Ichsanul
Published: February 2022

Putusnya suatu perkawinan berdasarkan putusan pengadilan yang berkekuatan hukum tetap (inkracht van gewijsde), Masalahan yang diteliti adalah bagaimana alas an dalam pemberian hak asuh anak akibat perceraian orang tua berdasarkan Kompilasi Hukum Islam dan UndangÃ¢â‚¬â€œUndang Perlindungan Anak, penelitian hukum ini adalah penelitian hukum normative atau doktrinal. Penelitian hukum ini, dikonsepkan sebagai apa yang tertulis di dalam peraturan Perundang-undangan (Low In Books) Penelitian dilakukan dengan cara meneliti bahan-bahan pustaka atau data sekunder yang terdiri dari bahan hukum primer, bahan hukum sekunder dan bahan hukum tertier. Gugatan perceraian yang dilakukanseorang suami dan isteri menimbulkan akibat terhadap anak-anaknya baik secara moril maupun materiil. Akibat dari perceraian yang pada umumnya sering timbul adalah tentang hadhanah atau yang bisa dikenal dengan Hak Asuh Anak. Apabila anak sudah mumayyiz (berumur 12 tahun) hendaklah diselidiki oleh yang berwajib siapakah di antara kedua orang tuanya yang lebih baik dan lebih cakap untuk mendidik anak tersebut.Ã‚Â Kata kunci : Hak Asuh, Nafkah, Perceraian.
علاقة جودة الحياة لدى الأمهات العاملات وغير العاملات بسلوكات أبنائهن
Authors: الألي الرافع , حرطاني أمينة
Published: February 2022

تهدف هذه الـدراسة إلى البحث في العلاقة بين جودة الحياة لدى الأمهات و المشكلات السلوكية عند أبنائهن وكذا البحث في إمكانية تأثر هذه العلاقة بمتغير عمل الأم. ولتحقيق أهداف الدراسة إستخدم المنهج الوصفي ، من خلال تطبيق استبيان جودة لحياة من إعداد الباحثتين ومقياس المشكلات السلوكية للأبناء (بعدما تم تكيفه على البيئة الجزائرية ) على عينة من 165 تلميذ(ة) يتابعون دراستهم بالمدارس الابتدائية لولاية سيدي بلعباس (الجزائر) و تتراوح أعمارهم مابين 10 إلى 13 سنة إلى جانب أمهاتهم (في الجموع 330 فردا). وقد توصلت الدراسة إلى أنه يوجد إرتباط دال إحصائيا وعكسي بين درجات الأبناء على مقياس المشكلات السلوكية ودرجات أمهاتهن على مقياس جودة الحياة . بالإظافة إلى أنه لا تتأثر العلاقة بين متغيري المشكلات السلوكية عند الأبناء و جودة الحياة لدى الأمهات بمتغير عمل الأم .
ANALISIS MANAJEMEN SUMBER DAYA INSANI PADA BANK PEMBIAYAAN RAKYAT SYARIAH
Authors: Sari Linda , Muhtadi Ridan , Mansur Mansur
Published: February 2022

Introduction: This study will analyze the human resource management at PT. BPRS Sarana Prima Mandiri Pamekasan in terms of recruitment and selection, training and employee development as well as employee performance appraisals.

Methods: The research methodology used by researchers is descriptive qualitative which will explain the events and circumstances in detail and perfectly with data collection techniques using observation, interviews and documentation.

Results: This research is deemed necessary considering that the development of Islamic banking in Indonesia is relatively fast but is still not balanced with adequate human resources, both in quality and quantity. and one of the company's mission is supported by human resources.

Conclusion and suggestion: This study indicates that human resource management at PT. BPRS Sarana Prima Mandiri (SPM) Pamekasan in terms of recruitment and selection is in accordance with sharia theory. Likewise, the work appraisal process is in accordance with the Islamic concept. However, in the training and development process, according to researchers, there is still a lack of material balance, namely between the material of Tauhid (Akhlak), Shari'ah, and Muamalah which is conveyed to employees when the training is carried out.

Keywords: Islamic banking, recruitment and selection, training and development, employee performance appraisal.
ANALISIS PENGARUH NILAI SPIRITUAL ZAKAT TERHADAP KESEJAHTERAAN MUZAKKI MELALUI PERILAKU IHSAN
Authors: Billah Zahida I’tisoma
Published: February 2022

Introduction: The importance of this research so that Muslim entrepreneurs realize the importance of obligations in issuing business zakat. And after they give zakat, it is expected that their behavior will be better in everyday life, especially in doing business so that they have a sociopreneurship entrepreneurial spirit. Therefore, the establishment of entrepreneur sociopreneurship through different activities by exploring spiritual values in issuing zakat is applied in business activities.

Methods: The analysis method in this research uses quantitative approach with measurement method using path analysis. The population used in this study was taken randomly, namely in the entrepreneurs in the field of culinary, services, and fashion in the city of Malang through the Ministry of Religious Affairs of Malang City. The number of samples amounted to the number of questions contained in the questionnaire multiplied by 5 which amounted to 110 entrepreneurs. With this approach, muzakki (entrepreneurs) are given a statement about spiritual motivation in issuing zakat in the form of values contained in zakat, namely: 1) the value of tawhid, 2) the value of humanity, 3) the value of belief in the existence of life after death.

Results: Based on this, the results found in the field and measurement using the analysis of the path, that the spiritual value of zakat can have a direct effect on the welfare of muzakki with a coefficient of determination of 0.64 while the indirect influence of spiritual value of zakat on the welfare of muzakki through ihsan behavior with a coefficient of determination of 0.38 because the person who spends zakat does not really understand the essence of spiritual value contained in zakat. Factors of wealth, descent, culture, education and the environment that make up a person is very determined in issuing zakat.

 

Keywords: spiritual value of zakat, Ihsan behavior, welfare
DAMPAK PENGARUH PEMBIAYAAN MURABAHAH TERHADAP PERKEMBANGAN UMKM SELAMA PANDEMI COVID-19
Authors: Dofiri Dhoqi , Istianah Istianah , Muhtadi Ridan
Published: February 2022

Introduction: The background of study is stimulated by the existance of micro-financing by using al-murabahah agreement at PT BRI Syariah branch of Bangkalan which is distributed to business people on level of medium, small and micro who need loan as the additional venture capital. Based on the explanation above, the research problems are; the condition of UMKM customers at BRI Syariah, especially the bangkalan people and the influence of Murabahah financing conducted by BRI Syariah on UMKM people in Bangkalan

Methods: The study applies the quantitative design in which the data collecting technique used are documentation, interview and questionnaire. Data analysis and processing technique used are SPSS which consist of simple linear regression, correlation test, t-test and excel percentage. The implementation time of this research was carried out in October 2020.

Results: The result of the study are: (1) the actors of medium, small and micro business level in bangkalan have taken the murabahah financing at PT. BRI Syariah branch of Bangkalan as the additional venture capital that they has run, and (2) murabahah financing at PT. BRI Syariah branch of Bangkalan is very influential on the development of UMKM people in Bangkalan. It can be measure by the increasing of the income as 236%.

Keywords: Micro, Small and Medium Enterprises (MSMEs), al-murabahah finance, income, UMKM development.
2021/36 No discrimination of reduced hours employees (DK)
Authors: Clasen Christian K.
Published: February 2022

2021/36 No discrimination of reduced hours employees (DK)

In four recent cases, the Danish Eastern High Court addressed the question of whether it was indirect disability discrimination to dismiss four reduced hours employees (fleksjobbere) as part of a cost-saving process because they lacked essential core skills. The High Court ruled in favour of the employer, stating that the employer was not required to maintain the employees’ employment as it would be incompatible with the new demands for qualifications caused by the cutbacks. Consequently, the dismissals did not constitute indirect disability discrimination.
2021/38 An employee can be both a permanent and a fixed-term employee with the same employer at the same time (IR)
Authors: O’Mahoney Sarah
Published: February 2022

2021/38 An employee can be both a permanent and a fixed-term employee with the same employer at the same time (IR)

The Irish High Court has determined that, pursuant to the definitions of ‘employment contract’ and ‘fixed-term employee’ in the Protection of Employees (Fixed-Term Work) Act 2003 (the ‘2003 Act’), a permanent employee temporarily upgrading to a more senior role on a fixed-term basis, was entitled to protection under the 2003 Act as a fixed-term employee despite the fact that he had the right to revert to his substantive terms and conditions as a permanent employee. The Court held that Council Directive 1999/70/EC on fixed-term work (the ‘Directive’) was not only concerned with an employee’s entitlement to continued employment, but also the nature, quality and terms and conditions of that employment. While Member States have the discretion to provide more favourable treatment to a broader category of employees than the Directive required, they could not define terms left undefined in the Directive or framework agreement on fixed-term contracts so as to arbitrarily exclude certain categories of workers from protection as ‘fixed-term workers’.
2021/39 Lapse of the right to paid annual leave: how does Max Planck apply to a manager? (NL)
Authors: van der Stel Tessa
Published: February 2022

2021/39 Lapse of the right to paid annual leave: how does Max Planck apply to a manager? (NL)

The Arnhem Court of Appeal has examined whether an employee was reasonably able to take leave, applying the ECJ’s Max Planck and Kreuziger judgments. According to the Court, the employer did not violate its obligation to inform the employee regarding the lapse of the right to paid annual leave. The Court stated that the employee was reasonably able to take leave, despite being incapacitated for work due to sickness. The Court ruled that the employee was not entitled to an allowance in lieu of untaken paid annual leave, as the right to such leave had lapsed.
2021/40 School director and loss of right to leave due to non-fulfilment of duties (RO)
Authors: Suciu Andreea , Mănăilă Teodora
Published: February 2022

2021/40 School director and loss of right to leave due to non-fulfilment of duties (RO)

The Dolj Tribunal has ascertained that a former employee, while acting as school director, by not fulfilling her obligations to schedule the annual leave of school teachers, including herself, cannot claim against the school as the employer for not providing the opportunity to take the annual leave or to inform of the possibility of losing such right. Furthermore, such actions of the former director will lead to the loss of the right to request compensation in case of termination of employment.
Tweede evaluatie van de Wet afbreking zwangerschap
Authors: Ploem M.C. , Krol E. , Legemaate J. , Winter H.B.
Published: February 2022

Tweede evaluatie van de Wet afbreking zwangerschap. Wat gaat de wetgever met de principiële kwesties doen?

In 2019-2020 werd de Wet afbreking zwangerschap (Wafz) voor de tweede keer geëvalueerd. In hun bijdrage staan de auteurs (die het evaluatieonderzoek uitvoerden) met name stil bij twee belangrijke thema’s van de evaluatie: de reikwijdte van de wet; en besluitvorming over abortus. Hun hoofdconclusie is dat er op dit moment geen aanleiding is de wet als zodanig op de schop te nemen. Niettemin zijn er op korte termijn wel belangrijke reparaties van de Wafz nodig, zoals ten aanzien van de buitengrenzen van de wet en de beraadtermijn.
Kroniek rechtspraak Europees recht 2019-2021
Authors: Groot N.A.D. , Verduijn M.A.M. , Rijken J.J.
Published: February 2022

Kroniek rechtspraak Europees recht 2019-2021

Deze kroniek bevat een overzicht van de rechtspraak van het Hof van Justitie van de Europese Unie (HvJ EU) en het Gerecht van de Europese Unie (Gerecht EU) op het gebied van het gezondheidsrecht in de afgelopen twee jaar. De precieze kroniekperiode is 1 april 2019 tot 1 november 2021.
Multi-staged Feature-Attentive Network for Fashion Clothing Classification and Attribute Prediction
Authors: Shajini Majuran , Ramanan Amirthalingam
Published: February 2022

In the visual fashion clothing analysis, many researchers are attracted with the success of deep learning concepts. In this work, we introduce a multi-staged feature-attentive network to attain clothing category classification and attribute prediction. The proposed network in this work brings out a landmark-independent structure, whereas the existing landmark-dependent structures take up a lot of manpower for landmark annotation and also suffers from inter- and intra-individual variability. Our focus on this work is intensifying feature extraction by incorporating low-level and high-level feature fusion within fashion network. We are aiming on multi-level contextual features which utilise spatial and channel-wise information to create contextual feature supervision. Further, we enclose a semi-supervised learning approach to escalate fashion clothes analysis that utilises knowledge sharing among labelled and unlabelled data. To the best of our knowledge, this is the first attempt to investigate the semi-supervised learning in fashion clothing analysis by adopting multitask architecture which simultaneously study the clothing categories as well as its attributes. We evaluated the proposed approach on large-scale DeepFashion-C dataset while unlabelled dataset obtained from six publicly available fashion datasets. Experimental results show that the proposed architectures for supervised and semi-supervised learning entailing deep convolutional neural network outperforms many state-of-the-art techniques considerably, in fashion clothing analysis.
Genetic basis of atrial firbrillation – the role of microRNA
Authors: Błaszczyk Robert , Kłoda Mateusz
Published: February 2022

Atrial fibrillation is the most common arrhythmia in adults. In addition to the well-known cardiovascular risk factors, the role of genetic factors in the pathogenesis of atrial fibrillation is emphasized. MicroRNAs are
a group of small, endogenous, single-stranded, non-coding RNAs, 20-22 nucleotides long, whose task is to regu­late gene expression at the post-transcriptional level. Changes in the expression of microRNAs in circulating blood and tissues lead to the development of cardiovascular diseases, including atrial fibrillation, leading to the remodeling of the heart muscle. Different types of remodeling, such as electrical remodelling, struc­tural remodeling, autonomic nerve remodelling, calcium handling abnormalities and single nucleotide polymorphisms in microRNA and related genes are responsible for the development and maintenance of atrial fibrillation. This paper presents the most important microRNAs that regulate genes that influence atrial fibrillation and thus may induce arrhythmia.
Endovascular solution in a complex post-dissectional thoracic aortic aneurysm case
Authors: Duvan İbrahim , Sürer Süleyman , Melike Şenkal Aygül , İnce İlker , Kızıltepe Uğursay
Published: February 2022

A 45-year-old male patient presented to our clinic with a post-dissectional thoracic aortic aneurysm with the retrograde filling of the false lumen. He previously underwent a Bentall operation and a proximal thoracic endovascular aortic repair. We carried out a bare metal stent implantation concomitant with endograft extension and stent-assisted balloon-induced intimal disruption and relamination procedure consecutively. Although true lumen expansion was achieved, the aneurysmatic dilation of the descending thoracic aorta was kept on expanding due to perfusion of the false lumen by the distal re-entries. Therefore, it was decided to perform a totally false lumen thrombosis by the candy-plug technique. In conclusion, despite being a fatal disease, endovascular treatment of post-dissectional thoracic aortic aneurysm post-dissectional thoracic aortic aneurysm is possible in anatomically suitable patients with a stepwise approach in experienced endovascular centers.
Simultaneous coronary artery disease and achalasia surgery: A novel approach
Authors: Benetis Rimantas , Budrikis Algimantas , Gazdziauskas Jonas
Published: February 2022

A 69-year-old female patient presented to cardiac surgery department with unstable angina due to severe coronary artery disease. Coronary artery bypass grafting was indicated; however, the patient's symptoms of achalasia, previously treated by the pneumatic dilatation, exacerbated. Subsequently, the patient underwent simultaneous surgery. After sternotomy, on cardiopulmonary bypass, esophagus was exposed and Heller myotomy was performed. Following cardioplegia, coronary artery bypass grafting was completed. The postoperative course was uneventful, and the patient was discharged on postoperative Day 9. In conclusion, this novel surgical technique can be effectively used in such cases.
Cilostazol induces angiogenesis and regulates oxidative stress in a dose-dependent manner: A chorioallantoic membrane study
Authors: Etli Mustafa , Karahan Oğuz , Akkaya Özgür , Basri Savaş Hasan
Published: February 2022

Background: In this study, we aimed to investigate the effects of cilostazol on angiogenesis and oxidative stress using the chorioallantoic membrane model.

Methods: In this experimental study, the Ross 308 chick embryos were used. The negative control group (n=10) received no intervention. The positive control group (n=10) consisted of eggs treated with epidermal growth factor for inducing angiogenesis. Three cilostazol groups were designed with 10-7 (n=10), 10-6 (n=10), and 10-5 (n=10) M concentrations. Each egg was punctured on the sixth day of incubation, and drug pellets were introduced to the positive control and drug groups at the prespecified doses. Vascular development was evaluated on the eighth day of application. The total oxidant status, total antioxidant capacity, and oxidative stress index levels were determined from albumen liquids obtained with a syringe before and after drug application.

Results: Lower oxidative stress index levels were obtained from the positive control and cilostazol groups compared to the negative control albumens (p=0.001). The increments in vascular junctions and newly developed vascular nodules were evaluated in drug-free and drug-applied chorioallantoic membranes. The highest activity was obtained in the 10-7 M concentration cilostazol group. An increased angiogenic activity was detected in all drug groups in each concentration compared to the negative control group (p=0.001). Angiogenic activity was similar in all the cilostazol-treated groups (p=0.43).

Conclusion: Cilostazol has a positive stimulant effect on angiogenesis and it seems to suppress oxidative stress during embryonic growth. Cilostazol exerts these effects significantly and similarly at different doses.