bluuebunny/crossref_metadata_2025 huggingface dataset:
cAMP сoncentrations in cardiac mitochondria and serum in the С57ВL/6 mice under independent melanoma В16/F10 growth versus melanoma В16/F10 growth linked to chronic neurogenic pain
Authors: Kit O.I. , Frantsiyants E.M. , Bandovkina V.A. , Neskubina I.V. , Shikhlyarova A.I. , Kaplieva I.V. , Surikova E.I. , Pogorelova Y.A. , Cheryarina N.D. , Trepitaki L.K. , Goroshinskaya I.A. , Vaschenko L.N. , Shatova Y.S. , Kuchkina L.P. , Kovalenko V.A. , Nemashkalova L.A.
Published: June 2022

The aim of this research work is to study the cAMP level in the cardiac mitochondria and serum in the С57ВL/6 strain mice of both genders under the independent melanoma В16/F10 growth versus the melanoma В16/F10 growth linked to chronic neurogenic pain (CNP). Materials and methods. Mice of strain С57ВL/6 (n=336) have been grouped as follows: the intact group of the mice (♂n=21; ♀n=21), the reference group (♂n=21; ♀n=21) with the reproduced CNP model, the comparison group (♂n=63; ♀n=63) to include the mice with melanoma В16/F10, and the main test group (♂n=63; ♀n=63) to cover the mice with the melanoma growth against the CNP background. Upon expiration of 1 week, 2 and 3 weeks of the melanoma growth, in the animals of the above experimental groups the cardiac mitochondria have been isolated with the centrifugation using high-performance refrigerated centrifuge Avanti J-E, BECMAN COULTER, USA. With ELISA Kit (RayBio USA) we have determined cAMP concentrations in serum and in the cardiac mitochondria. Results. CNP has induced a decrease in the cAMP level in the cardiac mitochondria by a factor of 3,6 in the female mice only. In the animals of the comparison group the cAMP level in the heart has been increasing beginning with week 2 of the tumor growth on average by a factor of 4, while in the main test group starting from week 1 of the tumor growth it has been recorded 2-4 times higher and was depleted by the end of the experiment. As to the cAMP concentration in serum, the dynamics thereof has not been found to be in correlation with the cardiac mitochondrial data, and its concentration decrease has been recorded both in the females and the males. Conclusion. So, the changes in the cAMP concentration in the cardiac mitochondria demonstrate their gender-specific feature; the female mice as against the males have responded to an independent impact produced by CNP. As to the main test group, CNP has stimulated an increase in the cAMP level in the cardiac mitochondria 1 week earlier than it is the case with the comparison group, and it has resulted in the full cAMP depletion by the 3rd week of the experiment.
Dental Health Status of Children in the Jember Regency's Agroindustry Environment
Authors: Sulistiyani Sulistiyani , Setyorini Dyah , Mubarok Akhmad Syahrul
Published: June 2022

Caries is one of the most common dental health issues, particularly in children. Caries develops over time due to the interaction of bacteria on the tooth surface, plaque or biofilm, and diet, resulting in the demineralization of hard tooth tissue. School-age children frequently consume food and beverages with no knowledge of which foods and beverages may increase the risk of dental caries. This study aims to identify the ICDAS caries index used to describe children's dental health status in Nogosari Elementary School grades I-III. Descriptive observational research with a cross-sectional approach was used. The sample in this study consisted of 76 students from grades I-III, employing the total sampling method. The collected data were entered into the examination form, discussed descriptively, and presented in tabular form. There were 823 caries-free teeth and 929 carious teeth in each unit. Caries reaching the pulp (ICDAS code 6) were the most severe caries found in children, affecting 50 children. As a result, there were no caries-free children. The dental health of Negeri Nogosari Elementary School children's of grades I-III in Kebun Renteng's agro-industrial environment was relatively poor. The number of caries-infected teeth was 53% higher than the number of caries-free teeth. There were no caries-free children in grades I-III, and the most severe dental caries discovered were caries that reached the pulp (ICDAS code 6).
Cadena de valor de semiconductores: estructura y perspectivas de cara al nuevo escenario global
Authors: Filippo Agustín , Guaipatín Carlos , Navarro Lucas , Wyss Federico
Published: June 2022

Factores externos están causando disrupciones en la cadena de suministros de semiconductores a nivel global, comprometiendo la competitividad de sectores intensivos en tecnología. Como respuesta, las empresas están analizando la relocalización de sus eslabones y los gobiernos están anunciando mecanismos de incentivos para atraer inversiones. La cadena de semiconductores está compuesta de segmentos que demandan distintos niveles de disponibilidad e inversión en capital, ID y talento. México tiene oportunidades para insertarse de mejor manera en la cadena global de valor de semiconductores. Este documento presenta una descripción de la cadena global de valor de los semiconductores, los problemas de abastecimiento que enfrenta y las respuestas de política de los países de la cadena, para contribuir a entender su complejidad y contar con antecedentes sobre los eslabones en donde existe una oportunidad de desarrollo para las empresas mexicanas.
Recursive Sentiment Detection Algorithm for Russian Sentences
Authors: Poletaev Anatoliy Y. , Paramonov Ilya V.
Published: June 2022

The article is devoted to the task of sentiment detection of Russian sentences. The sentiment is conceived as the author's attitude to the topic of a sentence. This assay considers positive, neutral, and negative sentiment classes, i.e., the task of three-classes classification is solved. The article introduces a rule-based sentiment detection algorithm for Russian sentences. The algorithm is based on the assumption that the sentiment of a phrase can be determined by the sentiments of its parts by the recursive application of appropriate semantic rules to the sentiments of its parts organized as a constituency parse tree. The utilized set of semantic rules was constructed based on a discussion with experts in linguistics. The experiments showed that the proposed recursive algorithm performs slightly worse on the hotel reviews corpus than the adapted rule-based approach: weighted $F_1$-measures are 0.75 and 0.78, respectively. To measure the algorithm efficiency on complex sentences, we created OpenSentimentCorpus based on OpenCorpora, an open corpus of sentences extracted from Russian news and periodicals. On OpenSentimentCorpus the recursive algorithm performs better than the adapted approach does: $F_1$-measures are 0.70 and 0.63, respectively. This indicates that the proposed algorithm has an advantage in case of more complex sentences with more subtle ways of expressing the sentiment.
Application of Election Functions to Estimate the Number of Monotone Self-Dual Boolean functions
Authors: Bystrov Leonid Y. , Kuzmin Egor V.
Published: June 2022

One of the problems of modern discrete mathematics is R. Dedekind problem on the number of monotone boolean functions. For other precomplete classes, general formulas for the number of functions of the classes had been found, but it has not been found so far for the class of monotone boolean functions. Within the framework of this problem, there are problems of a lower level. One of them is the absence of a general formula for the number of boolean functions of intersection $MS$ of two classes --- the class of monotone functions and the class of self-dual functions. In the paper, new lower bounds are proposed for estimating the cardinality of the intersection for both an even and an odd number of variables. It is shown that the election function of an odd number of variables is monotone and self-dual. The election function of an even number of variables is determined. Free election functions, which are functions with fictitious variables similar in properties to election functions, are introduced. Then the union of a set of election functions and a set of free election functions is considered, and the cardinality of this union is calculated. The resulting value of the cardinality is proposed as a lower bound for $|MS|$. For the class $MS$ of monotone self-dual functions of an even number of variables, the lower bound is improved over the bounds proposed earlier, and for functions of an odd number of variables, the lower bound for $|MS|$ is presented for the first time.
COVID-19 from the lens of Global International Relations
Authors: Bas Vilizzio María Magdalena , Nieves Aguirre Mónica Fernanda
Published: June 2022

Aunque el inicio de la vacunación contra la covid-19 trajo esperanza, el Fondo Monetario Internacional pronostica que la principal falla en la recuperación global es el acceso a las vacunas, argumento que refuerza la idea de que la covid-19 es una sindemia y no una pandemia. Este artículo sostiene que, desde la perspectiva de las relaciones internacionales globales, tres elementos impactan en el acceso y asequibilidad de la vacuna: la seguridad humana, la gobernanza global y el derecho internacional. En primer lugar, la emergencia sanitaria requiere repensar la seguridad considerando múltiples riesgos y amenazas centrados en el ser humano. Asimismo, la ineficacia de la gobernanza global condujo al éxito de la diplomacia de las vacunas sobre el Mecanismo Covax, así como a una larga e incierta lucha de India y Sudáfrica por una suspensión temporal de las patentes en la Organización Mundial del Comercio. Finalmente, si bien el derecho juega un papel fundamental en la construcción de resiliencia en situaciones de vulnerabilidad, el sistema internacional carece de tratados sobre pandemias o que establezcan límites a la propiedad intelectual si la inmunidad de rebaño así lo requiere.
Air Quality Forecasting in DKI Jakarta Using Artificial Neural Network
Authors: Anggraini Asfilia Nova , Ummah Nisa Kholifatul , Fatmasari Yessy , Hayati Holle Khadijah Fahmi
Published: June 2022

The increase in the use of motorized vehicles increases air pollution conditions, especially in big cities such as the capital city of Indonesia, Jakarta. The pollution that pollutes this city contains various kinds of chemical particles that are harmful to living things when they enter the body. several efforts to reduce this pollution have been carried out, one of which is by identifying the pollutants contained in the air. This study uses data obtained from monitoring stations to predict the content of pollutants in the air at some time in the future. the method used is data mining forecasting with a neural network model. by using rapid miner obtained several graphic descriptions of pollutant conditions in Jakarta that go up and down. pollutant levels of SO2, CO, PM10 and NO2 all increased in the November-December period and at the same time period, ozone was at its lowest point. Results from Prediction air quality using Artificial Neural Network with 5 parameters, shown on this pollutant PM10 had an RMSE of 9,477; SO2 had an RMSE 5,474; CO had an RMSE 8,392; O3 had an RMSE 18,250; NO2 had an RMSE 5,171. Can be concluded that the RMSE value of O3 is higher than the others and the lowest value of NO2.
Light Drop Resistor (LDR) as pH Sensor for Wastewater Treatment
Authors: Saukani Imam
Published: June 2022

Industri elektro plating menghasilkan limbah saat beroperasi, diantaranya berupa limbah cair asam atau basah. Pengolahan limbah yang tidak benar akan menimbulkan masalah yang sangat serius bagi lingkungan. Sesuai dengan pasal 1 ayat 7 UU RI tahun 1997 Pencemaran lingkungan adalah masuknya atau dimasukkannya makhluk hidup, zat, energi, atau komponen lain ke dalam lingkungan dan atau berubahnya tatanan lingkungan oleh kegiatan manusia atau oleh proses alam, sehingga kualitas lingkungan turun sampai tingkat tertentu yang menyebabkan lingkungan menjadi kurang atau tidak berfungsi lagi sesuai peruntukannya. Proses pembacaan kadar cairan limbah asam atau basah dengan memanfaatkan sensor LDR (Light Drop Resistor). Nilai resistansi sensor LDR akan berubah berbanding lurus dengan kondisi keasaman ato tingkat kebasahan, nilai inilah yang akan menjadi dasar untuk diolah diproses kontrol selanjutnya. Pengambilan data dilakukan dengan memasang seri sensor LDR dengan sebuah resistansi dan didapat hasil senagai berikut, bahwa air limbah yang sangat keruh, gelap, penyaringan pertama, penyaringan kedua dan jernih, masing-masing kondisi tersebut mengeluarkan  tegangan 4,4volt, 3,45volt, 3,10volt, 2,6volt, 0,2volt Kata Kunci — Elektro plating, limbah cair, light drop resistor, sensor, asam, jernihAbstract - The electro plating industry produces waste when operating, including acid or wet liquid waste. Improper waste treatment will cause very serious problems for the environment. In accordance with article 1 paragraph 7 of the RI Law of 1997, environmental pollution is the entry or inclusion of living things, substances, energy, or other components into the environment and or changes in the environmental order by human activities or by natural processes, so that the quality of the environment decreases to a certain level which cause the environment to become less or no longer function according to its designation. The process of reading acid or wet waste liquid levels by utilizing an LDR (Light Drop Resistor) sensor. The resistance value of the LDR sensor will change directly proportional to the conditions of acidity or level of wetness, this value will be the basis for further control processing. Data retrieval is done by installing a series of LDR sensors with a resistance and the following results are obtained, that the wastewater is very cloudy, dark, first filtering, second filtering and clear, each of these conditions emits a voltage of 4.4 volts, 3.45 volts, 3 ,10volt, 2.6volt, 0.2volt      Eko Nuraini is with the ATK Polytechnic, Ministry of Industry, Yogyakarta, Indonesia (corresponding author provide phone +6281228130765; email ekonuraini@gmail.com)Imam Saukani., is with Department Electrical  of State Polytechnic  Malang , Indonesia.( e-mail: mam_im@yahoo.com).Keywords — Electro plating, liquid waste, light drop resistor, sensor, acid, clear
The Cultural Aspects and Economic Performance of Small Wixarica Artisan Businesses
Authors: Correa García Luis Ángel
Published: June 2022

The Huichol or Wixarika culture is one of the most important in Mexico. They are carriers of traditions transmitted from generation to generation. Their customs have been present since ancient times. They have values that are fundamental for the union of their community. From the theoretical approach of Resources and Capabilities, this empirical study aims to analyze how the cultural aspects influence the economic performance of small wixarika artisan businesses. The methodology used was multiple regression analysis. The construct “cultural aspects” was elaborated based on the literature review. The results show that the customs variable, measured through “making of handcrafted pieces as his parents taught him,” influences the income from the business. The variables tradition inherited from generation to generation and the values that parents instill in the business do not influence their economic performance. It concludes with the need to dignify and value the work of the artisans.
A cigány/roma közösségek kutatásának hazai irányai és legismertebb eredményei
Authors: Láczay Magdolna
Published: June 2022

A magyar többségi társadalomban félévezrede ismertek a cigány közösségek. A források azonban szegényesek, és csak az életük néhány területére adnak információt. A szórványosan, kis létszámban érkező népcsoport definiálására akkor vállalkozott a tudomány néhány tudósa, amikor létszámuk jelentősen megnőtt. A 20. század második felében előbb a levéltárosok és a néprajztudósok kutatták, honnan származnak, van-e közös történelmük, honnan ered a nevük, milyen sajátos jellemzők alakítják az életformájukat, nyelvüket, kultúrájukat, hiedelemvilágukat. Eredményeik alapján kisebbségként definiálták őket, de mára Európában már 10-12 millióra becsülik a létszámukat.  A cigány/roma történelemnek vannak naiv kutatói és szószólói, akik a régmúlt dicsőségét és a meghurcoltatásokat vélik megtalálni, de a tudományos kutatásokban, napjainkban egyre elfogadottabb az a nézet, hogy az elmúlt évszázadok európai és magyarországi, cigány/roma gyűjtőnéven ismert közösségek sem történeti, sem néprajzi, sem szociológiai szempontból nem írhatók le homogén, differenciálatlan entitásként. A cigány/roma embereket, illetve közösségeket a történelem folyamán nem ugyanazok a kritériumok tették cigánnyá/romává, ezért őket elsődlegesen a társadalmi helyzetük alapján kell megismerni, hogy integrálódásuk lehetővé válhasson, és az iskolázásnak, a kötelező foglalkoztatásnak, a cigánytelepek felszámolásának hazai és uniós programjai valóságos társadalmi felemelkedési utakat nyithassanak.
Women’s Meaningful Participation in Water Security
Authors: Herbert Sian
Published: June 2022

This rapid literature review explores gender transformative practices and the meaningful participation of women in water security. There is large and growing literature base on gender and water, with most of it coming from a health, or sanitation and hygiene perspective, and most focussing on access, quality, and women as vulnerable water users and or women and water in rural communities (de Silva, Veilleux & Neal, 2018). There has been a growth in focus on women’s participation in water governance, and particularly a more recent focus on meaningful participation. However, as yet, the literature is much more limited in this latter area, and the practical advances in women’s meaningful participation (“gender transformative processes”) in water security have also been more limited than progress in other areas (Ozano, et al., 2022). This rapid review found a lot of literature focusses on a few countries including: Kenya, India, and Nepal. As de Silva, et al. (2018, p.212) explain in their work on transboundary water, there is limited evidence on “the role of women as agents of change within a decision-making, transboundary water context and almost every paper that promised to do so in some way, ended up focusing on specific developing countries and women as direct water users”. As for the effectiveness of certain practices over others, and over different timeframes, there is little empirical information on this, yet there are a lot of critical reflections in the literature on the broad barriers to meaningful participation. And there are general recommendations for how to make progress on this agenda. This rapid review is indicative of the most commonly discussed issues in the literature, but is not inclusive of all of the many related issues.
Transformational Leadership on Women's Leadership in Islam
Authors: Rouzi Kana Safrina , Purnomo Halim , Mustakim Muh. , Bin Husen Ismail Faisal
Published: June 2022

This paper describes a transformational leadership review of women's leadership in Islam. This study aims to explain leadership concepts that combine women's leadership qualities (gentleness, balance, courage, feelings of compassion, wisdom and integrity) with several characteristics in transformational leadership theory which include moral, self-confidence, vision, environmental orientation, inspiring and charismatic and then integrate with the Qur'anic text on leadership in Islam. This review results that women adopt a participatory and democratic leadership style which is the character of transformational and Islamic leadership.
Does ASEAN Protect Minority Groups During Pandemic?
Authors: Mochtar Yusnan Hadi
Published: June 2022

The COVID-19 pandemic discourse in the Association of Southeast Asian Nations (ASEAN) context is very state-centric. Many analysts also offered militaristic and economic views. Sadly, the discussion related to minority groups is underexplored. This paper aims to fill the literature gaps by identifying multi-stakeholder efforts in the region in protecting the groups during the pandemic. It matters to examine because ASEAN has political complexities particularly when it comes to the issue. It is important to notify that minority groups refer to refugees, indigenous people, and other vulnerable groups. This research used the library research method by collecting data from journal articles, official reports, news, and public discussions. This paper also consists of three layers of analysis; (1) how the member states in ASEAN region protect the groups during a pandemic; (2) how the civil society organizations (CSOs) promote and advocate their rights; (3) and it also provides policy recommendations for policymakers to aware more on this issue.
Persepsi Dan Strategi Adaptasi Petani Kubis Terhadap Dampak Perubahan Iklim Di Desa Sumberrejo Kecamatan Ambulu Kabupaten Jember
Authors: Faiqoh Dwi Nurul , Hani Evita Soliha
Published: June 2022

Perubahan iklim adalah ancaman serius bagi sektor pertanian.Kubis adalah salah satu tanaman hortikultura yang terdampak oleh terjadinya perubahan iklim. Salah satu wilayah penghasil kubis adalah Desa Sumberrejo Kecamatan Ambulu Kabupaten Jember. Petani kubis di desa tersebut mengalami kendala akibat dampak dari perubahan iklim berupa cuaca tidak tentu. Berdasarkan permasalahan tersebut, peneliti tertarik untuk mengetahui: 1) Hubungan antara karakteristik petani kubis dengan persepsinya terhadap dampak perubahan iklim pada usahatani kubis, dan 2) Strategi adaptasi perubahan iklim yang dilakukan petani. Daerah penelitian ditentukan secara sengaja (purposive method). Metode penelitian yang digunakan adalah metode analitis dan deskriptif. Sampel penelitian ditentukan menggunakan metode proportional random sampling dengan jumlah 35 orang. Data yang digunakan adalah data primer hasil wawancara dan data sekunder. Hasil penelitian menunjukkan: 1) Karakteristik petani kubis di Desa Sumberrejo yang memiliki hubungan signifikan dengan persepsinya terhadap dampak perubahan iklim adalah jumlah tanggungan keluarga, sedangkan karakteristik lain yaitu umur, tingkat pendidikan, pengalaman usahatani, dan luas lahan memiliki hubungan tidak signifikan. 2) Strategi adaptasi yang dilakukan petani adalah menggunakan dolomit, menggeser waktu panen, meningkatkan interval pengairan, mendalamkan sumur atau membuat sumur baru, meningkatkan interval penyemprotan insektisida, meningkatkan dosis insektisida, menambah jenis insektisida, menggunakan insektisida nabati, menggunakan perangkap lekat, memasang jaring mengelilingi lahan, menanam tanaman refugia, memasang lampu sebagai perangkap hama, dan mengendalikan hama secara manual.

Kata kunci: Perubahan iklim, persepsi petani, strategi adaptasi
Manifestaciones y política en los inicios de la Universidad: Antonio Marrero Hernández, Lorenzo Olarte Cullen y Jerónimo Saavedra Acevedo en diálogo con Antonio María Martín Rodríguez
Authors: Marrero Hernández Antonio , Olarte Cullen Lorenzo , Saavedra Acevedo Jerónimo , Martín Rodríguez Antonio María
Published: June 2022

"Diálogo Vivo ULPGC" es un proyecto editorial del Servicio de Publicaciones y Difusión Científica de la Universidad de Las Palmas de Gran Canaria, que pretende conservar, en formatos audiovisual e impreso, la memoria y la historia de la ULPGC a través del diálogo entre sus protagonistas. En este cuarto volumen, tres personalidades decisivas para la creación de nuestra universidad, Jerónimo Saavedra Acevedo, Lorenzo Olarte Cullen y Antonio Marrero Hernández, dialogan con el director del Servicio de Publicaciones. La sesión fue grabada el 28 de septiembre de 2021 en el Paraninfo de la ULPGC y en ella los tres intervinientes, dos expresidentes del Gobierno de Canarias y el presidente de la Comisión Gestora que apoyó la creación de una universidad plena para Gran Canaria, comparten sus experiencias sobre las convulsas circunstancias políticas y sociales que caracterizaron aquellos momentos: la oposición de la Universidad de La Laguna a la creación de otra universidad canaria, el movimiento social que alentó el proceso, las reticencias de los principales partidos políticos, la afortunada pirueta jurídica que ofreció un resquicio para la aprobación de la nueva universidad, cuando parecía imposible a la vista de la composición entonces del gobierno autonómico, las dificultades y penurias de las incipientes enseñanzas universitarias en Gran Canaria… y una lúcida reflexión sobre los retos de una universidad de hoy, con algunas recetas seguramente drásticas, pero tal vez necesarias.
Evaluación del taurodontismo en radiografías panorámicas en una población peruana
Authors: Alvarez Acevedo Brenda Silvana , Ruiz García de Chacón Vilma Elizabeth
Published: June 2022

El taurodontismo es una alteración en la morfología dentaria, la cual tiene implicancias clínicas en diferentes áreas de la odontología. Objetivo: Evaluar el taurodontismo en radiografías panorámicas en una población peruana. Material y métodos: Se evaluaron 220 radiografías panorámicas digitales en las que se clasificó el tipo de taurodontismo en primeros molares permanentes según el método de Shifman y Chanannel. Las observaciones fueron registradas en una ficha de datos. Resultados: El 51% pertenecieron al sexo masculino y el 49 % al femenino. La frecuencia de taurodontismo según sexo, fue mayor en hombres en 24%, y en mujeres fue 20%. El tipo de taurodontismo más frecuente fue el hipotaurodontismo en un 80%. La localización y la primera molar más frecuente fue el maxilar superior con un 68% y la molar superior izquierda con un 37%, respectivamente. Conclusión: La evaluación de taurodontismo en radiografías panorámicas digitales se caracterizó por ser más frecuente en hombres, en cuanto al tipo y localización resultó ser más frecuente el hipotaurodontismo y maxilar superior respectivamente. Además, se caracterizó por ser más frecuente en los primeros molares superiores del lado izquierdo.
Enfermedad von Willebrand: consideraciones prácticas para el odontólogo. Revisión de literatura.
Authors: Navas-Aparicio María del Carmen , Acuña-Navas Alejandro
Published: June 2022

La enfermedad von Willebrand es el desorden hemorrágico hereditario más común, que se origina por la deficiencia del factor von Willebrand, la cual provoca una adhesión y agregación plaquetaria defectuosa. Se caracteriza por un tiempo de sangrado y tiempo parcial de tromboplastina prolongados, con bajos valores del factor VIII, y aumento de fragilidad capilar, pero con recuento normal de plaquetas. El tratamiento odontológico en un paciente con enfermedad von Willebrand, debe ser individualizado de acuerdo con la severidad de la condición del paciente, así como coordinado con el hematólogo, quien debe de determinar el tipo de enfermedad y la necesidad de la terapia de reemplazo del factor según diagnóstico específico previo al manejo de este. Mediante esta revisión bibliográfica se desea reforzar el conocimiento al odontólogo de este trastorno hemorrágico, ya que con ello se pueden evitar o minimizar posibles complicaciones de sangrado durante el tratamiento odontológico.
Trabajo colaborativo en el manejo de malformaciones faciales congénitas.
Authors: Laquihuanaco Loza Felipe Santiago , Laquihuanaco Coarita Gina Maritza
Published: June 2022

El sistema de servicios de salud en el Perú es fragmentado y segmentado, en este nuevo siglo se requiere de una actitud coordinada y cooperativa entre los profesionales de la salud. Las malformaciones labio alveolo palatinas, son anomalías congénitas más frecuentes de la región bucomaxilofacial, afecta el crecimiento y desarrollo de estructuras orofaciales de las dos terceras partes de la cara, alterando reflejos orales innatos como la mordida, succión, deglución y la capacidad de la cavidad bucal para permitir acumulación de presión. Un desempeño adecuado en los servicios de salud se logra con una visión y postura compartida entre los integrantes del equipo de trabajo, sumada a una gestión eficaz, para lo cual la práctica colaborativa interprofesional requiere de cambios de paradigma, en el que se demuestre una evidencia sustancial e irrefutable de una cultura de equipo y un entorno interdisciplinario confiable, reconociendo responsabilidad compartida en los resultados.
A Rare Case of Neuroendocrine Tumor Following Radical Nephrectomy
Authors: Ishaq Muhammad Rozaqy , Febriansyah Nafis Audrey , Soetojo Soetojo
Published: June 2022

Highlights:

Rare occurrence of a large, well-differentiated primary renal neuroendocrine tumor in a young man.
Identifying primary renal NET from the workup and histological examination of renal tumors needs to be done to understand more of this infrequent type of tumor.

 
Abstract:
Neuroendocrine Tumors (NETs) are a diverse range of neoplasms with various biological and histologic features and therapeutic responses. The prevalence of primary renal carcinoids is scarce worldwide. At the moment, complete surgical resection is the primary treatment against primary neuroendocrine tumors of the kidney. Nephrectomy followed by the lymph node dissection is a standard procedure for localized primary renal NETs. Since renal carcinoid tumor is extremely rare, we decided to present a unique case of a 25-years-old male with neuroendocrine renal carcinoid tumor following radical nephrectomy. The results indicated a solid, solitary tumor verified on the frozen section because a postoperative CT–scan showed a recurring mass in the renal fossa following radical nephrectomy. The case emphasized the need to investigate primary renal NET in the workup and histological examination of renal tumors and also contributed to our understanding of this infrequent clinical entity.
Cognitive, Motor, and Language Assessment in Children with Human Immunodeficiency Virus
Authors: Budi Apsari Putu Indah , Supadma I Nyoman , Kumara Wati Ketut Dewi , Dharma Artana I Wayan
Published: June 2022

Highlights:

HIV-infected children had lower capute scores than normal children.
HIV child age range 12-24 months almost suffer delayed speech, and were in suspect criteria was founded.

 
Abstract:
The cognitive, motor and language aspect of HIV-infected children is an important issue affecting their quality of life. The capute scale, divided into Cat and Clams scores, is commonly used to assess children's cognitive, motor, and language functions. This study assessed Cat and Clams’ scores of HIV-infected children. We performed Cat and Clams assessment on 136 children consisting of 68 HIV-infected children and 68 normal children as control aged 0-36 months. The Capute scale examined both groups at the first meeting (first month), and for the rest six months, we evaluated the progress of cognitive, motor, and language development. In the first meeting, we found that HIV-infected children had significantly low capute scores than the control group. The sixth-month Capute score in HIV-infected children was also significantly lower than the control group. HIV-infected children had lower Capute scores than normal children.
Patient Satisfaction, Perception-Expectation Gap, and Costumer Satisfaction Index in Annual Survey 2021 at Dr. Soetomo General Academic Hospital
Authors: Prakoeswa Cita Rosita Sigit , Hidayah Nur , Dewi Arlina , Purnamasari Indah , Adriansyah Agus Aan , Yaqub Amak M.
Published: June 2022

Highlights:

Customers expectations at Dr. Soetomo General Academic Hospital has a higher quality of service.
The handling of complaints has a low performance on the quality of services at Dr. Dr. Soetomo General Academic Hospital.
Improving service quality requires improvements in efficient complaint handling.

 
Abstract:
Service quality is essential in health institutions that can affect patient satisfaction and loyalty. The growth in the number of patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, triggered the diversification of services that require periodic quality control. This study aimed to investigate the performance of 31 departments/units in the hospital, the level of customer satisfaction with services provided, and factors that could influence satisfaction. A survey about service performance, perception, and expectation of services was carried out in 31 departments/units using questionnaires from August to October 2021. Convenient respondents consisted of 2121 patients and their families aged >15. Questionnaire items assessed performance, perceptions, and expectations of health services using the SERVQUAL method. Statistical Package for the Social Sciences (SPSS) software was used to perform an analysis of the results of the measurement and the difference in responses between demographic groups of respondents (p<0.05 was significant). The mean performance score was 92.86, and the gap between their perception and expectation averaged -0.23. Customers' expectations of the provider's competence were met, and its performance was perceived to be the best. Meanwhile, handling complaints was perceived as having the lowest performance, while customers’ satisfaction over it had not been met. The results showed that the hospital could still not fully meet some of the customer expectations, with immediate improvements needed in handling complaints.
A First Step to Novel Approach for Treating Alkali Injury of the Cornea: Effect of Platelet Rich Fibrin Lysates on Cultured Rabbit (Oryctolagus cuniculus) Limbal Stem Cell Proliferation Exposed by Sodium Hydroxide
Authors: Prabawati Wahyu Endah , Suhendro Gatut , Retnowati Endang
Published: June 2022

Highlights:

Sodium hydroxide causing platelet rich fibrin stimulates limbal stem cell proliferation in chemical trauma.
Limbal stem cell niche and influences limbal stemness was repaired by Platelet Rich Fibrin.

 
Abstract:
Chemical injuries of the eye produce extensive damage to the ocular surface and limbal stem cells, resulting in permanent unilateral or bilateral visual impairment. Alkali injuries occur more frequently than acid injuries. Platelets are a rich source of potential wound healing, promoting polypeptide growth factors. This study aimed to investigate the effect of platelet-rich fibrin (PRF) lysates on limbal stem cell proliferation, which was exposed to sodium hydroxide that resembled limbal stem cell deficiency due to chemical trauma. Confluent rabbit (Oryctolagus cuniculus) limbal stem cells wounded using 20µL of 0.00625 M sodium hydroxide (pH 13) were treated with platelet-rich fibrin lysates (PRF) (0, 5, and 10%). PRF lysates were prepared from peripheral rabbit blood according to Choukroun's method without using anticoagulant and foreign factors for platelet activation. The proliferation of limbal stem cells was measured by a 3-(4,5-dimethylthiazol-2-yl)-2.50 diphenyl tetrazolium bromide (MTT) colorimetric assay at 24, 48, and 72 hours after exposure to sodium hydroxide. Proliferation significantly increased limbal stem cells with PRF lysates 5% (p<0.01) and 10% (p<0.01) group compared with the control (PRF 0%). There was no significant difference between PRF lysates of 5% and 10% (p>0.01). The highest proliferation of limbal stem cells was found in the PRF lysates 5% group after 48 hours (100.24%). PRF stimulated limbal stem cell proliferation in chemical trauma caused by the sodium hydroxide model. PRF repaired the limbal stem cell niche and influenced the limbal stemness. The present findings warrant further research on PRF as a novel alternative treatment for limbal stem cell deficiency.
Prediction of Load Capacity in Microgrid by Multiple Regression Method
Authors: Marchenko Rostyslav Serhiiovych , Klen Kateryna Serhiivna
Published: June 2022

The article presents the results of load power forecasting in Microgrid systems by multiple regression with a forecast range of one day. energy sources, as well as tools for storage, redundancy and load management. The design and construction of such systems is cost-effective, as these systems are powered by renewable energy sources, which is attractive due to subsidies and discounts on energy distribution - the so-called "green tariff". depends on weather conditions, such as temperature, pressure, humidity, wind speed and direction, cloudiness, etc., the task of predicting the load capacity depending on environmental parameters is relevant. Therefore, a forecast model of load capacity based on environmental data is developed and its software implementation is given. The daily curves of changes in load power with a discreteness of one hour are presented. Daily curves of load capacity changes on weekdays and weekends are also provided. A free resource has been selected to download the environmental database. A specific day is set for load forecasting. Hourly values ​​of environmental data (temperature, pressure, humidity) for a given day are given. The criteria for finding such days according to the environmental data are selected and the allowable percentage difference of mathematical expectation and variance of the relevant data is established. The parameters of mathematical expectation and variance of a given day are calculated. The statistical dependence between load data and environmental data is calculated. Regressive equations of the found similar days are constructed, on the basis of which the regressive forecast equation of loading capacity for days ahead is received. The daily curve of the forecasted load is presented and the comparative schedule of the forecasted with the real value of the load is constructed. The accuracy of the prediction is estimated using the average absolute error of MAPE. The algorithm and results of work of the developed program on which search of a similar day and calculation of forecast value for forecasting of power of loading for days ahead are represented are resulted.
Revised rollover measure: an application to Euronext’s wheat futures contract
Authors: ARABA Narjiss , François-Heude Alain
Published: June 2022

This article extends an existing model on contracts rollover, that allows us to lower the bound measuring the number of contracts rolled by verifying that the difference between the number of contracts opened and closed is non negative. This new model is later applied to a futures contract (on milling wheat), to better understand the hedging activity that takes place, and in particular to increase our knowledge on the behavior of hedgers.
On the Risk Management of Demand Deposits and Interest Rate Margins
Authors: CHERRAT Hamza
Published: June 2022

This paper deals with risk mitigation of interest rate margins related to banks demand deposits. We assume that demand deposits are linked to interest rates and business risk, which cannot be fully hedged on financial markets. The dynamics of forward market rates follows a standard market model (i.e. BGM model). The demand deposit is the monetary amount put in to account by clients. It is accounting in M1 (monetary aggregate 1). Using a linear regression, the deposit rates are related to the market rates in linear ways. We take the viewpoint of an asset and liability manager focusing on the bank's net operating income at a given quarter according to standard accounting rules. We use the static hedging strategies for bank deposit. We illustrate our results using data from 1997 -- 2019 for both US and Euro zones. This allows us to illustrate and compare the hedging of the interest rate margin for these two main zones, for which the deposit rate setting are clearly different (roughly speaking, in the US zone the deposit rate is equal to about half of the interest rate while, in the Euro zone, the two rates are much closer).
Indicated Role of Small Cellular Particles in Mediating Inter-Species Interaction for Removal of Bisphenols from Conditioned Media
Authors: Skufca David , Bozic Darja , Hocevar Matej , Jeran Marko , Bedina Zavec Apolonija , Kisovec Matic , Podobnik Marjetka , Tomazin Rok , Matos Tadeja , Iglic Ales , Griessler Bulc Tjasa , Heath Ester , Kralj-Iglic Veronika
Published: June 2022

Small cellular particles are released into the surroundings of cells and are proposed to play an important role in intercellular communication and consequently the responses of microbial com-munities to environmental stressors. We studied the connection between the small cellular parti-cles and the efficiency of three culture series of the microalge Phaeodactylum tricornutum and bac-teria (axenic microalgae, bacterial culture and co-culture of the two) in removing bisphenols from their growth medium. The microorganism growth rate was determined by flow cytometry, protein profiles were examined by protein gel electrophoresis, cultures and small cellular particle isolates were imaged by scanning electron microscopy, and bisphenols were analyzed using gas chroma-tography coupled with tandem mass spectrometry (GC-MS/MS). Higher growth rates of microal-gae were observed in the co-culture than in the axenic microalgal culture, while the presence of bisphenols neither influenced the morphology of the microalgal cells, protein profiles, nor the small cellular particle isolates. Biotic removal of bisphenols ranged from 0% to 71% and differed among the culture series in a compound-specific manner. However, it remains unclear which mechanisms influenced algal growth and bisphenol removal. Further research on the mechanisms of interspecies communication is needed to advance our understanding of microbial communities at the nano-level.
A Dataset Containing Tweets and Their Meta Data for Understanding Social Media Conversations around Movies during Their Release
Authors: Michielsen Joost , Lelli Francesco
Published: June 2022

In this paper we intend to present a dataset that contain a collection of tweets generated as reactions of the release of 50 different movies. The dataset can be used for gaining useful insights regarding the conversation that is generated around a particular movie. It is particularly suitable for conducting sentiment analysis and other NLP techniques. The dataset contains approximately 2.5 million tweets with their related meta data and cover 50 movies. For each movie, its IMDb rating is included. The movies are the 25 releases with the highest number of votes during 2020 and 2021. The collected tweets represent the reactions of the twitter community during the first week of the release date in US of that particular movie. The tweets per movie ranged from 1.000 to approximately 200.000 tweets with an average of 50.000 per release. We used The Internet Archive Wayback Machine in order to retrieve the IMDb movie rating after one week of the US release date. The tweets and related metadata have been collected using the Tweet Downloader tool.
Preparation and Highly Enhanced Eelectrocaloric Effect in a Bimodal-Structured 0.9KNbO3-0.1BaTiO3 Solid Solution at Room Temperature
Authors: Zhang Hongfang , Liu Liqiang , Gao Ju , Kwok K.W. , Lu Sheng-Guo , Kong Ling-bing , Peng Biaolin , Hou Fang
Published: June 2022

The bimodal grain-size distribution 0.9KNbO3-0.1BaTiO3 ceramics, with a typical perovskite structure in tetragonal phase at room temperature, were successfully prepared by an induced abnormal grain growth (IAGG) method at a relatively low sintering temperature. In this bimodal grain-sized distribution structure, the extra-large grains (about 10‒50 μm) were evolved from the micron-sized filler powders and the fine grains (about 0.05‒0.35 μm) were derived from the sol precursor matrix. The 0.9KNbO3-0.1BaTiO3 ceramics exhibit relaxor-like behavior with the diffused phase transition near room temperature, and confirmed by the existence of the polar nanodomain regions (PNRs) using the HRTEM images. The large room-temperature electrocaloric (EC) effect was found, characterized by an adiabatic temperature drop of 1.5 K, an isothermal entropy change of 2.48 J kg-1 K-1, and high EC strengths of ïDT/DEï = 1.50×10-6 KmV-1 and DS/DE = 2.48×10-6 Jmkg-1K-1V-1directly measured under E = 1.0 MV/m. These excellent ECEs demonstrate that this simple IAGG method is highly appreciated for synthesizing high-performance EC materials for efficient cooling devices.
Распространение вариантов вируса SARS-COV-2, вызывающих озабоченность (VOC) на основе количества их геномов, депонированных в базу данных GISAID за неделю с 11.06.2022 г. по 17.06.2022 г.
Authors: Дмитриева Людмила , Краснов Ярослав , Чумачкова Елена , Осина Наталья , Зимирова Анастасия , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Щербакова Светлана , Кутырев Владимир
Published: June 2022

В обзоре представлена информация по актуальным геновариантам вируса SARS-COV-2, циркулирующим в настоящее время, геномные последовательности которых размещены в международной базе данных GISAID за неделю с 11.06.2022 г. по 17.06.2022 г.
Research Advance on Prediction and Optimization for Fracture Propagation in Stimulated Unconventional Reservoirs
Authors: Huang Luoyi , Lu Mingjing , Sheng Guanglong , Gong Jie , Ruan Jiayu
Published: June 2022

Multistage stimulation horizontal wells are prerequisite technologies for efficient development of unconventional reservoir. However, the induced fracture network morphology from hydraulic fracturing is very complex and affected by many factors, such as the in situ stress, rock mechanical properties, and natural fracture distribution. The large numbers of natural fractures and strong reservoir heterogeneity in unconventional reservoirs result in enhanced complexity of induced fractures from hydraulic fracturing. Accurate description of fracture network morphology and the flow capacity in different fractures form an important basis for production forecasting, evaluation (or optimization) of stimulation design, and development plan optimization. This paper focuses on hydraulic fracturing in unconventional reservoirs and discusses the current research advances from four aspects: (1) the prediction of induced fracture propagation, (2) the simulation of fluid flow in complex fracture networks, (3) the inversion of fracture parameter (fracture porosity, fracture permeability, etc.), and (4) the optimization of hydraulic fracturing in unconventional reservoirs. In addition, this paper provides comparative analysis of the characteristics and shortcomings of the current research by outlining the key technical problems in the study of flow characterization, parameter inversion, and optimization methods for stimulation in unconventional reservoirs. This work can provide a certain guiding role for further research.
Factores de riesgos asociados a la inasistencia de control prenatal y consecuencias maternoperinatal durante el estado de emergencia por la COVID-19 en el Centro Materno Infantil Carlos Mariategui 2021
Authors:   , Quispe Andahua Maria del Carmen , Rosales Rivas Rosa Maria
Published: June 2022

Introducción: La asistencia del control prenatal es un problema de salud pública que involucra tanto el bienestar de la madre como del recién nacido, pero durante la pandemia por COVID-19, el sistema de salud ha sufrido cambios severos que influyen en el incremento de inasistencias del control prenatal. El objetivo de este estudio es determinar cuáles son los factores de riesgo que se asocian a la inadecuada asistencia de controles prenatales y sus complicaciones materno perinatal como resultado secundario, durante el estado de emergencia por la COVID-19 en el “Centro materno Carlos Mariátegui”. Método: Estudio observacional, no probabilístico por conveniencia, analítico: caso y control en 160 puérperas atendidas en el “Centro Materno José Carlos Mariátegui”, divididas 80 con abandono de controles prenatales (casos) y 80 sin abandono de controles prenatales (controles). Resultados: La edad promedio de los casos fue 28.05 ± 0.72 años. El 48% de estas contaba con educación secundaria. Factores como el ser estudiante (OR: 1.89 IC:95% 0.33-10.76), gran multípara (OR: 2.08 IC:95% 0.68-6.31) y un periodo intergenésico corto (OR: 1.88 IC:95% 0.67-5.30), aumentaron el riesgo de abandonar los controles prenatales. Dentro de los que tuvieron atonía uterina el 83.33% presentaron controles prenatales insuficientes comparado con el 16.67% que tuvieron controles prenatales suficientes, existiendo 5.57 veces más riesgo de presentar la complicación (OR: 5.57 IC 95% 1.12 - 53.51). Conclusión: Se concluye que no existe asociación entre el miedo al COVID-19 y el grupo con controles prenatales insuficientes, debido a los cambios recientes respecto al control de propagación de la enfermedad y sus complicaciones, como la aplicación de la vacuna contra el COVID-19 a la población y grupos de alto riesgo como gestantes. Mientras se evidencio que existe asociación entre atonía uterina y controles los controles prenatales insuficientes, debido que a las faltas de control prenatal...