bluuebunny/crossref_metadata_2025 huggingface dataset:
Meta-analysis of the diagnostic performance of circulating microRNAs for pancreatic cancer
Authors: Peng Cheng , Li Zhiqiang , Huang Lihua , Gao Wenzhe , Wang Jiale , Liu Yunfei , Li Xia , Yu Xiao
Published: December 2019

Background: Pancreatic cancer (PC) is characterized by high malignancy and poor prognosis. Detection of circulating microRNAs (miRNAs) is one of the liquid biopsy approaches. Numerous researches have suggested that some differentially expressed miRNAs may be promising diagnostic markers for PC, but the results varied among studies. The present study aimed to summarize the diagnostic accuracy of circulating miRNAs, carbohydrate antigen 19-9 (CA19-9), and the combination of miRNAs and CA19-9. Methods: A literature search of online databases including Pubmed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI) and WanFang was conducted. Relative data were extracted from eligible included studies and a meta-analysis was performed. Results: A total of 46 studies involving 4,326 PC patients and 4,277 non-PC controls were included. The pooled SEN, SPE, and AUC of circulating miRNAs in differentiating PC from non-PC controls were 0.79 (0.77-0.81), 0.77 (0.75-0.79), and 0.85 (0.81-0.87), respectively. For CA19-9, the SEN, SPE, and AUC were 0.78 (0.75-0.80), 0.90 (0.85-0.94) and 0.85 (0.82-0.88), respectively. The combination of miRNAs and CA19-9 greatly improved the SEN, SPE, AUC to 0.84 (0.80-0.87), 0.91 (0.89-0.93) and 0.94 (0.92-0.96), respectively. Circulating miRNAs also yielded an acceptable diagnostic accuracy for early-stage PC with a SEN of 0.79 (0.76-0.82), a SPE of 0.74 (0.68-0.79) and an AUC of 0.81 (0.77-0.84). Conclusions: Circulating miRNAs exhibited a satisfactory diagnostic performance for PC, even early-stage PC. The combination of circulating miRNAs and the traditional marker CA19-9 can further improve the diagnostic accuracy, providing a novel strategy for PC diagnosis.
Predictive value of gamma-glutamyl transpeptidase to lymphocyte count ratio in hepatocellular carcinoma patients with microvascular invasion
Authors: Zhang Hongxing , Zhou Yu , Li Yicheng , Qin Wanying , Zi Yunhua , Liu Yulan , Qiu Xiaoying , Xu Hongyuan , Liao Weijia , Huang Zhaoquan
Published: December 2019

Purpose: Microvascular invasion (MVI) is an independent risk factor for poor prognosis of hepatocellular Carcinoma (HCC), However, there is still a lack of preoperative markers to predict MVI of HCC. This study intends to explore the potential application value of gamma-glutamyl transpeptidase to lymphocyte count ratio (GLR) in predicting MVI of HCC, and provide guidance of clinical diagnosis and treatment.Patients and methods: From March 2010 to December 2015, 230 HCC patients underwent surgical treatment in Affiliated Hospitals of Guilin Medical University were selected. Clinicopathological parameters between MVI group (n = 115) and non-MVI group (n = 115) were comparative analyzed. Gamma-glutamyl transpeptidase (GGT) to lymphocyte count ratio (GLR) was used as the key risk factor of HCC with MVI and its optimal cut-off value was estimated by using the receiver operating characteristic (ROC) curve. Kaplan-meier method was used to analyze the survival of HCC patients, and univariate and multivariate Cox regression analysis were used to establish independent predictors affecting postoperative HCC patients.Results: The level of GLR in the MVI group and non-MVI group was 84.83 ± 61.84 and 38.42 ± 33.52 (p < 0.001) respectively. According to the ROC curve analysis, the optimal cut-off value of GLR was 56, and the area under ROC curve (AUC) was 0.781 (95%CI, 0.719 - 0.833) for risk prediction in HCC patients with MVI. Multivariate analysis results showed that the tumor size > 5 cm, HCC combined with MVI and GLR > 56 are independent risk factors for poor prognosis of HCC patients. In addition, compared with non-MVI group, patients with MVI had shorter progression-free survival (PFS) rates and overall survival (OS).Conclusion: GLR could be a predictive biomarker of HCC after operation and a potential predictor of HCC patients combined with MVI.
New molecular approach for the detection of Kinetoplastida parasites of medical and veterinary interest
Authors: Medkour Hacène , Varloud Marie , Davoust Bernard , Mediannikov Oleg
Published: December 2019

Background Kinetoplastids are a remarkable group of protists, containing a range of ubiquitous free-living species–pathogens of invertebrates, vertebrates and even some plants. Trypanosoma species cause sleeping sickness and Chagas disease, whereas the leishmaniases kill and debilitate hundreds of thousands of people worldwide. The diagnosis of a series of pathogenic kinetoplastids is based on clinical manifestations, epidemiological and laboratory data and, for laboratory methods, a gold standard is often missing for human or animal patients. The aim of this study was to implement a molecular approach for the diagnosis and study of Kinetoplastida. Methods The TaqMan qPCR assays targeting: the 24Sa LSU for Kinetoplastida, 28S LSU for Leishmania/ Trypanosoma spp., 5.8S rRNA for Trypanosoma spp., 18S SSU for Leishmania spp., Kinetoplast minicircle DNA (kDNA) L. donovani complex and the L. infantum specific qPCR were designed, validated for their sensitivity and specificity in silico and then in vitro using a panel of known DNAs and after that they were used in the screening of 369 blood samples (358 dogs, 2 equids, 9 monkeys) . In addition, the new 28S LSU primer sets are presented for use in Kinetoplastida's identiﬁcation by PCR and sequencing. Results All qPCR assays showed high analytical sensitivities without failures. They detect about 0.01 parasite/ mL blood for the kDNA based qPCR and at least a single cell-equivalent of rDNA for the other systems. Based on the sequencing results, after screening, sensitivity (Se) and specificity (Sp) were: 0. 919 and 0.971, 0.853 and 0.979, 1.00 and 0.987, 0.826 and 0.995 for all of Kinetoplastida, Leishmania/ Trypanosoma, Trypanosoma, Leishmania spp. specific qPCRs, respectively. kDNA based qPCRs were more sensitive and specific (Se: 1.00; Sp: 0.997). PCR and sequencing allowed the detection of Kinetoplastids in animal blood samples such as: L. infantum, L. guyanensis, T. congolense, T. evansi and Bodo spp.. Conclusion The molecular approach proposed in this study is useful in epidemiological studies, in fundamental research such as screening for new Kinetoplastida species, in diagnosis and therapeutic follow-up. In addition, researchers are free to choose the molecular tools adapted to their studies.
Assessment of knowledge, attitude and practices and analysis on risk factor regarding schistosomiasis among fishermen and boatmen in Dongting Lake Basin, P.R. China
Authors: Guan Zhou , Dai Si-Min , Zhou Jie , Ren Xiao-Bing , Qin Zhi-Qiang , Li Yin-Long , Lv Shan , Li Shi-Zhu , Zhou Xiao-Nong , Xu Jing
Published: December 2019

Background: Fishermen and boatmen are high risk population to get infection by schistosomes due to their high frequency water contact in endemic areas of schistosomiasis in the People’s Republic of China (P. R. China). To develop specific interventions towards this population, understanding their knowledge, attitude and practices (KAPs) towards schistosomiasis and exploring risk factors for schistosomiasis are necessary. Therefore, our present study was designed to assess the KAPs of fishermen and boatmen and to identify the risk factors associated with schistosome infection based on a cross-sectional survey in selected area. Methods: A cross section survey was conducted in Dongting Lake Basin of Yueyang County, Hunan Province, P. R. China. A total of 601 fishermen and boatmen were interviewed from October to November in 2017. Information regarding socio-demographic details and knowledge, attitude, and practices toward schistosomiasis were collected through a standardized questionnaire. Meanwhile, fecal samples of participants were collected and detected by Polymerase Chain Reaction (PCR) technique to understand the infection status of schistosomes among fishermen and boatmen. Results: Of the 601 interviewed participants, more than 90% respondents knew the way of getting infection, intermediate host of schistosomes and preventive methods, while majority of the respondents knew this disease and its cause, clinical manifestations and transmission mode properly. The majority of the respondents had positive attitude towards schistosomiasis prevention. However, only 6.66% respondents had installed latrine on their boats, while 32.61% respondents defecated in the public toilets on shore. In addition, only 4.99% respondents protected themselves while contacting freshwater. The overall positive rate of schistosome nucleic acid among fishermen and boatmen in Yueyang County was 13.81% (83/601). Multivariate logistic regression analysis showed that age, years of doing current job, times receiving treatment and whether treated in last two years were the main influencing factors of S. japonicum infection among this population. Conclusions: Fishermen and boatmen are still at high risk of infection in China, and gaps existed between knowledge, attitude and practices toward schistosomiasis in this population group. Chemotherapy, health education encouraging behavior change in combination with other integrated approaches to decrease the transmission risk in environments should be strengthened.
Sexual-biased gene expression of olfactory-related genes in the antennae of Conogethes pinicolalis (Lepidoptera: Crambidae)
Authors: Jing Dapeng , Zhang Tiantao , Bai Shuxiong , He Kanglai , Prabu Sivaprasath , Luan Junbo , Wang Zhenying
Published: December 2019

Background Conogethes pinicolalis (Lepidoptera: Crambidae), is similar to Conogethes punctiferalis (yellow peach moth) and its host plant is gymnosperms, especially for masson pine. So far, less literature was reported on this pest. In present study, we sequenced and characterized the antennal transcriptomes of male and female C. pinicolalis for the first time. Results Totally, 26 odorant-binding proteins (OBP) genes, 19 chemosensory proteins (CSP) genes, 55 odorant receptors (OR) genes and 20 ionotropic receptors (IR) genes were identified from the C. pinicolalis antennae transcriptome and most of them were olfactory genes, amino sequences were annotated against homologs of C. punctiferalis. The neighbor-joining tree indicated that the amino acid sequence of olfactory related genes is highly homologous with C. punctiferalis. Furthermore, the reference genes were selected, and we strongly recommended the GAPDH or RP49 to verify gene expression for larvae development and RP49 or RPL13 for adult tissues. Conclusions Our study provides a starting point on the molecular level characterization between C. pinicolalis and C. punctiferalis, which might be a supportive for pest management studies in future.
Peculiarities of the institutional blocks of the Ukrainian higher education system in the conditions of economic transformation
Authors: Chernukha Тetyana
Published: December 2019

Problems of influence of informatization and globalization processes on all the components of human economic activity and, accordingly, on a fundamental and rapid change in the requirements for educational and qualification characteristics of the specialists involved in the production of goods and services in general, and the mechanisms and instruments of providing educational services themselves, in particular, are quite rightly the focus of the researchers. Such a structural change of the national economy necessitated a substantial correction of the Ukrainian higher education system. Аs a result of the study, the influence of socio-cultural factors on the organization of institutional support of the Ukrainian educational space is revealed. The specific features of the institutional structure of the higher education system of Ukraine are highlighted and discussed. Based on a comparative approach, the article presents an analysis of the institutional blocks of the higher education system. The content of transformations in the mechanisms of structural and functional complementarity of institutional elements of the higher education system of Ukraine is revealed, namely the maintenance of structural complementarity of elements of the institutional system in the sphere of industrial relations is revealed, the peculiarities of the institutional block of financing are analyzed, the specifics of the institutional block of corporate governance is determined, the content of the institutional block of production models is revealed, the peculiarities of the training of the teaching staff of the higher education institution within the institutional block “training, preparation, and advanced training” are determined. The understanding of the transformation in the process of economic globalization of the role and importance of higher education systems as a key tool for ensuring the entry of the national economy into the nucleus, proto-periphery or periphery (orientation to knowledge transfer) of the capitalist world-system was improved.
Evaluation and analysis of factors influencing the financial sustainability of engineering enterprises
Authors: Berest Maryna , Merenkova Ljubov
Published: December 2019

Financial sustainability is one of the most important characteristics of an enterprise's financial position. It determines the level of the company independence from external entities and sources of financing, and, in turn, is conditioned by a set of multifaceted factors. In the case of negative influence of the external environment, engineering enterprises require research and selection of factors of influence on financial sustainability, which are formed in the internal environment of their functioning. The content analysis of definitions of the "financial stability of an enterprise" concept is carried out. Given the analysis results, the key informative characteristics of the enterprises are emphasized, such as state and structure of financial resources, solvency and profitability of the enterprise. In the context of selected areas and based on comparative analysis of literature sources and methods recommended at the state level for assessing the enterprise financial status, the study has formed a list of coefficients, the calculation and analysis of which is appropriate in evaluating assessment of financial enterprises. Using regression analysis, the study has revealed factors that most significantly influence the level of financial sustainability of engineering enterprises. It is established that the level of financial stability of the mechanical engineering industry enterprises in Kharkiv region is mainly influenced by the level of security of current liabilities of enterprises with financial current assets, the ability of enterprise assets to generate net profit and the share of equity in the financing sources structure. Therefore, to ensure the financial sustainability of engineering companies, management should take measures to ensure that they have a sufficient level of financial assets to cover their current liabilities and to optimize financial results in the context of increased net profit.
Sensitivity analysis of the DEM resolution and effective parameters of runoff yield in the SWAT model: a case study
Authors: Nazari-Sharabian Mohammad , Taheriyoun Masoud , Karakouzian Moses
Published: December 2019

This study investigates the impact of different digital elevation model (DEM) resolutions on the topological attributes and simulated runoff, as well as the sensitivity of runoff parameters in the Mahabad Dam watershed in Iran. The watershed and streamlines were delineated in ArcGIS, and the hydrologic analyses were performed using the Soil and Water Assessment Tool (SWAT). The sensitivity analysis on runoff parameters was performed, using the Sequential Uncertainties FItting Ver. 2 algorithm, in the SWAT Calibration and Uncertainty Procedures (SWAT-CUP) program. The results indicated that the sensitivity of runoff parameters, watershed surface area, and elevations changed under different DEM resolutions. As the distribution of slopes changed using different DEMs, surface parameters were most affected. Furthermore, higher amounts of runoff were generated when DEMs with finer resolutions were implemented. In comparison with the observed value of 8 m3/s at the watershed outlet, the 12.5 m DEM showed more realistic results (6.77 m3/s). Comparatively, the 12.5 m DEM generated 0.74% and 2.73% more runoff compared with the 30 and 90 m DEMs, respectively. The findings of this study indicate that in order to reduce computation time, researchers may use DEMs with coarser resolutions at the expense of minor decreases in accuracy.
Research on wind-induced nutrient release in Yangshapao Reservoir, China
Authors: Bai Yu , Gao Jinhua , Zhang Ying
Published: December 2019

Nutrient (total nitrogen (TN) and total phosphorus (TP)) are considered the major indicators to be impacted by wind speed in shallow lakes and reservoirs. As a reservoir situated in Jilin Province, China, Yangshapao Reservoir has been employed for irrigation and urban water use. After 2 years’ observation carried out on water quality and wind speed, it was found that the TN, NH4 and TP are significantly correlated with the bottom shear stress attributed to wind, whereas the dissolved phosphorus (DP) is not. Bottom shear stress is also noticeably associated with dissolved oxygen (DO), thus promoting nutrient release into the water body. In winter, ice can effectively inhibit the wind-induced shear stress, and the TP concentration is evidently lower than in the other seasons. This scenario should be considered in the management of the water quality of the lake and similar lakes.
Effect of transformational leadership and organizational culture on employee performance mediated by job motivation
Authors: Putra G. Ngurah Suteja , Dewi I Gusti Ayu Manuati
Published: December 2019

This study aims to analyze the effect of transformational leadership and organizational culture on employee performance mediated by job motivation. The population in this study included 134 Civil Servants in the Secretariat of the Bali District/City Election Commission with a total sample of 100 people using the proportional random sampling method. Data analysis techniques were performed using Structural Equation Modeling (SEM) with the Partial Least Square (PLS) approach. Job motivation is able to mediate the relationship between transformational leadership and organizational culture on employee performance partially. The Head of the Secretariat of the KPU of Regency/City in Bali needs to develop a transformational leadership style by providing motivation that inspires subordinates to work better when job motivation increases will be directly proportional to an increase in employee performance. In addition, a strong organizational culture such as information disclosure and participation of all members of the organization in achieving organizational goals can be developed continuously. When job motivation increases, it will encourage employees to improve the quality and timeliness of employees in completing work.
PENGARUH METODE LATIHAN DAN KOORDINASI TERHADAP POWER TUNGKAI ATLET BOLA VOLI JUNIOR PUTRI
Authors: Ismoko Anung Probo , Sukoco Pamuji
Published: December 2019

Penelitian bertujuan mengetahui: (1) Peningkatan power melalui metode latihan agility hurdle drills dan agility ring drills, (2) Perbedaan pengaruh metode latihan terhadap power tungkai, (3) Perbedaan pengaruh power tungkai antara yang memiliki koordinasi tinggi dan rendah, dan (4) Pengaruh interaksi antara metode latihan dan koordinasi terhadap power tungkai. Penelitian ini merupakan eksperimen. Populasi penelitian adalah atlet klub Bola Voli Spirit dan Pervas berjumlah 44 atlet. Sampel penelitian 24 atlet ditentukan dengan teknik sampling. Pengumpulan data menggunakan tes yang dilakukan sebelum dan sesudah perlakuan. Instrumen penelitian adalah Sargen Jump Test dan Hexagonal Obstacle Test. Teknik analisis data menggunakan ANAVA. Hasil penelitian adalah: (1) Tidak terdapat perbedaan peningkatan power tungkai yang signifikan melalui metode latihan agility hurdle drills dan agility ring drills. (2) Tidak terdapat perbedaan pengaruh antara metode latihan ter-hadap power tungkai. (3) Terdapat perbedaan peningkatan power tungkai antara yang memiliki koordinasi tinggi dan koordinasi rendah. (4) Tidak terdapat interaksi antara metode latihan dan koordinasi terhadap peningkatan power tungkai. THE EFFECT OF TRAINING MODELS AND COORDINATION ON THE LEG POWER OF JUNIOR FEMALE VOLLEYBALL ATHLETESAbstractThis study aimed to determine: (1) increase leg power through of agility hurdle drills and agility ring drills training models, (2) the differences in the effect of training models on the leg power, (3) differences in the effect of leg power between those having a high and low coordination, and (4) the effect interaction between training methods and coordination on the leg power.This study is an experimental study. The population in this study was the athletes of Volleyball Club Spirit and Pervas, totaling 44 athletes. A sample of 24 athletes was establised using the purposive sampling. The data were collected using tests and the measurements performed before and after treatment. The instru-ments used in this study was the Sargen Jump Test and Hexagonal Obstacle Test. The data were analyzed using the ANOVA. The results are: (1) There is no difference in effect between training methods of hurdle agility drills and agility ring drills on improved the leg power,  (2) There is no difference in effect between training methods on the leg power, (3) There are differences in the leg power improvement between those having high and low coordination. (4) There is no interaction between training methods and coordination on the improvement of leg power.Keywords: agility hurdle drills, agility drills ring, leg power, coordination, volleyball.
MODEL LATIHAN KETERAMPILAN GERAK PENCAK SILAT ANAK USIA 9-12 TAHUN
Authors: Iswana Bayu , Siswantoyo Siswantoyo
Published: December 2019

Penelitian ini bertujuan untuk menghasilkan model latihan keterampilan gerak pencak silat anak usia 9-12 tahun. Penelitian pengembangan mengadaptasi langkah-langkah penelitian pengembangan dari Borg & Gall (1983, p.775), (1) pengumpulan informasi, (2) analisis hasil informasi, (3) pengembangan produk awal, (4) validasi ahli dan revisi tahap 1, (5) ujicoba skala kecil dan revisi, (6) ujicoba skala besar dan revisi tahap 2, (7) produk final. Uji coba skala kecil dilakukan terhadap anak Tapak Suci SD N 1 Padokan dan Tapak Suci SD Muhamadiyah Demangan. Uji coba skala besar dilakukan terhadap anak Pagar Nusa Sleman, Pagar Nusa Kota Yogyakarta yang berlatih di SD N Demangan, Persatuan Hati Bantul. Instrumen pengumpulan data, (1) wawancara, (2) skala nilai, (3) pedoman observasi model, (4) pedoman keefektifan model. Teknik analisis data yang digunakan yaitu analisis deskriptif kuantitatif dan diskriptif kualitatif. Isi dari hasil produk di dalamnya terdapat 6 model latihan, (1) kucing dan tikus, (2) bentengan, (3) gobak sodor, (4) jala ikan, (5) berburu burung, (7) elang dan anak ayam. Para ahli menyimpulkan bahwa di dalam model terdapat aspek kognitif, afektif dan psikomotor, sehingga model layak dan efektif untuk digunakan.  A TRAINING MODEL FOR PENCAK SILAT MOVEMENT SKILLS OF CHILDREN AGED 9-12 YEARSAbstract This study aims to produce a training model for pencak silat (self-defence) movement skills of children aged 9-12 years. This research and development (R & D) study was conducted by adapting the R & D steps by Borg & Gall (1983, p.775), i.e. (1) information collection, (2) information result analysis, (3) preliminary product development, (4) expert validation and stage 1 revision, (5) a small-scale tryout and a revision, (6) a large-scale tryout and stage 2 revision, and (7) final product. The small-scale tryout was conducted by involving participants of Tapak Suci SD N I Padokan and Tapak Suci SD Muhamadiyah Demangan. The large-scale tryout was conducted by involving participants of Pagar Nusa Sleman and Pagar Nusa Yogyakarta City carrying out training in SD N Demangan and Persatuan Hati Bantul. The data collecting instruments included (1) interviews, (2) a score scale, (3) a model observation guide, and (4) a model effectiveness guide. The data were anlyzed using the quantitative and qualitative descriptive techniques. The contents of the product consist of six training models, i.e. (1) kucing dan tikus, (2) bentengan, (3) gobak sodor, (4) jala ikan, (5) berburu burung  and (6) elang dan anak ayam. The experts conclude that in the model there are cognitive, affective, and psychomotor aspects so that it is appropriate and effective to use. Keywords: model, training, pencak silat, children aged 9 – 12 years
KETERAMPILAN BERMAIN SEPAKTAKRAW ATLET PELAJAR DIY
Authors: Hananto Hubertus Purno , Rachman Hari Amirullah
Published: December 2019

Penelitian ini secara umum bertujuan untuk mengetahui pengaruh kemampuan koordinasi dan metode latihan terhadap keterampilan sepaksila atlet sepaktakraw pelajar DIY. Secara spesifik untuk mengetahui: (1) perbedaan keterampilan sepaksila ditinjau kemampuan koordinasi; (2) perbedaan keterampilan sepaksila ditinjau metode latihan; (3) ada tidaknya interaksi antara kemampuan koordinasi dan metode latihan terhadap keterampilan sepaksila pada atlet sepaktakraw pelajar DIY. Penelitian ini menggunakan metode eksperimen, dengan pendekatan faktorial 2x2 desain blok. Populasi penelitian ini adalah seluruh atlet sepaktakraw pelajar DIY, dan sampel diambil sejumlah 28 orang dengan teknik purposive sampling. Hasil penelitian: (1) ada perbedaan yang signifikan keterampilan sepaksila ditinjau kemampuan koordinasi (2) ada perbedaan yang signifikan keterampilan sepaksila ditinjau metode latihan dan (3) ada interaksi yang signifikan antara kemampuan koordinasi dan metode latihan terhadap keterampilan sepaksila pada atlet sepaktakraw pelajar DIY.  THE ABILITY OF PLAYING SEPAKTAKRAW WITHIN THE STUDENT ATHLETES OF THE SPECIAL REGION OF YOGYAKARTAAbstract This  study aims to investigate the effect of the coordination capabilities and training methods on the sepaksila skills of sepaktakraw student athletes in Yogyakarta Special Territiry (YST), especially to find out; (1) the difference in the sepaksila skills in terms of the coordination capabilities; (2) the difference in the sepaksila skills in terms of the training methods; (3) the interaction between the coordination capabilities and the training methods on the sepaksila skills of sepak satkraw student athletes in YST. This study employed the experimental method with the 2x2 factorial block design. The research population comprised all sepaktakraw student athletes in YST and the sampel, consisting of 28 athletes, was selected using the purposive sampling technique. The conclusions of the study are as follows. (1) There is a significant defference in the sepaksila skills in terms of the coordination capabilities; (2) There is a significant difference in the sepaksila skills in terms of the  training methods; (3) There is a significant interaction between the coordination capabilities ant the training methods on the sepaksila skills among the sepaktakraw student athletes in YST. Keywords: skills, sepaksila, coordination capabilities,training method,pair method, triple method.
PENGARUH AKTIVITAS BERMAIN DAN PERSEPTUAL MOTORIK TERHADAP KETERAMPILAN MOTORIK SISWA SEKOLAH DASAR KELAS BAWAH
Authors: Anggita Gustiana Mega , Rachman Hari Amirullah
Published: December 2019

Penelitian ini bertujuan untuk mengetahui pengaruh aktivitas bermain dan perseptual motorik terhadap keterampilan motorik siswa sekolah dasar kelas bawah. Penelitian ini adalah penelitian eksperimen menggunakan rancangan faktorial 2 x 2 dengan menggunakan tes awal dan tes akhir. Data dikumpulkan menggunakan tes dan pengukuran, menggunakan instrument general motor ability test dan tes kemampuan perseptual motorik. Analisis data menggunakan ANAVA dua jalan dan uji Tukey. Hasil penelitian menunjukkan sebagai berikut, (1) aktivitas bermain dengan alat memiliki pengaruh lebih besar dibandingkan aktivitas bermain tanpa alat terhadap keterampilan motorik. (2) Terdapat perbedaan antara model aktivitas bermain dengan alat dan model aktivitas bermain tanpa alat pada kelompok kemampuan perseptual motorik tinggi terhadap keterampilan motorik. (3) Tidak terdapat perbedaan antara model aktivitas bermain dengan alat dan model aktivitas bermain tanpa alat pada kelompok dengan kemampuan perseptual motorik rendah terhadap keterampilan motorik. (4) Terjadi interaksi antara model aktivitas bermain dan kemampuan perseptual motorik terhadap keterampilan motorik. Kata kunci: aktivitas bermain, kemampuan perseptual motorik, keterampilan motorik.
BACK MATTER (Indeks Subjek, Indeks Pengarang, Biografy, Author Guidelines)
Authors: - -
Published: December 2019

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A Real-Time Mobile Intervention to Reduce Sedentary Behavior Before and After Cancer Surgery: Usability and Feasibility Study (Preprint)
Authors: Low Carissa A , Danko Michaela , Durica Krina C , Kunta Abhineeth Reddy , Mulukutla Raghu , Ren Yiyi , Bartlett David L , Bovbjerg Dana H , Dey Anind K , Jakicic John M
Published: December 2019

BACKGROUND

Sedentary behavior (SB) is common after cancer surgery and may negatively affect recovery and quality of life, but postoperative symptoms such as pain can be a significant barrier to patients achieving recommended physical activity levels. We conducted a single-arm pilot trial evaluating the usability and acceptability of a real-time mobile intervention that detects prolonged SB in the perioperative period and delivers prompts to walk that are tailored to daily self-reported symptom burden.

OBJECTIVE

The aim of this study is to develop and test a mobile technology-supported intervention to reduce SB before and after cancer surgery, and to evaluate the usability and feasibility of the intervention.

METHODS

A total of 15 patients scheduled for abdominal cancer surgery consented to the study, which involved using a Fitbit smartwatch with a companion smartphone app across the perioperative period (from a minimum of 2 weeks before surgery to 30 days postdischarge). Participants received prompts to walk after any SB that exceeded a prespecified threshold, which varied from day to day based on patient-reported symptom severity. Participants also completed weekly semistructured interviews to collect information on usability, acceptability, and experience using the app and smartphone; in addition, smartwatch logs were examined to assess participant study compliance.

RESULTS

Of eligible patients approached, 79% (15/19) agreed to participate. Attrition was low (1/15, 7%) and due to poor health and prolonged hospitalization. Participants rated (0-100) the smartphone and smartwatch apps as very easy (mean 92.3 and 93.2, respectively) and pleasant to use (mean 93.0 and 93.2, respectively). Overall satisfaction with the whole system was 89.9, and the mean System Usability Scale score was 83.8 out of 100. Overall compliance with symptom reporting was 51% (469/927 days), decreasing significantly from before surgery (264/364, 73%) to inpatient recovery (32/143, 22%) and postdischarge (173/420, 41%). Overall Fitbit compliance was 70% (653/927 days) but also declined from before surgery (330/364, 91%) to inpatient (51/143, 36%) and postdischarge (272/420, 65%).

CONCLUSIONS

Perioperative patients with cancer were willing to use a smartwatch- and smartphone-based real-time intervention to reduce SB, and they rated the apps as very easy and pleasant to use. Compliance with the intervention declined significantly after surgery. The effects of the intervention on postoperative activity patterns, recovery, and quality of life will be evaluated in an ongoing randomized trial.
Internet and Health Information Technology Use and Psychological Distress Among Older Adults With Self-Reported Vision Impairment: Case-Control Study (Preprint)
Authors: Choi Namkee G , DiNitto Diana M , Lee Othelia EunKyoung , Choi Bryan Y
Published: December 2019

BACKGROUND

The number of older adults with vision impairment (VI) is growing. As health care services increasingly call for patients to use technology, it is important to examine internet/health information technology (HIT) use among older adults with VI.

OBJECTIVE

This study aimed to examine (1) the rates of internet/HIT use among older adults with VI compared with a matched sample of their peers without VI, (2) associations of VI with internet/HIT use, and (3) association of HIT use with psychological distress, assessed with the Kessler-6 screen.

METHODS

Data were obtained from the 2013 to 2018 US National Health Interview Survey. Older adults (aged ≥65 years) with self-reported VI were matched with older adults without VI, in a 1:1 ratio, based on age, sex, number of chronic medical conditions, and functional limitations (N=2866). Descriptive statistics and multivariable logistic regression models, with sociodemographic factors, health conditions, health insurance type, and health care service use as covariates, were used to examine the research questions.

RESULTS

In total, 3.28% of older adults (compared with 0.84% of those aged 18-64 years) reported VI, and 25.7% of them were aged ≥85 years. Those with VI were significantly more socioeconomically disadvantaged than those without VI and less likely to use the internet (adjusted odds ratio [aOR] 0.64, 95% CI0.49-0.83) and HIT (aOR 0.74, 95% CI 0.56-0.97). However, among internet users, VI was not associated with HIT use. HIT use was associated with lower odds of mild/moderate or serious psychological distress (aOR 0.62, 95% CI 0.43-0.90), whereas VI was associated with greater odds of mild/moderate or serious distress (aOR 1.84, 95% CI 1.36-2.49). Health care provider contacts were also associated with higher odds of internet or HIT use.

CONCLUSIONS

Compared with their matched age peers without VI, older adults with VI are less likely to use HIT because they are less likely to use the internet. Socioeconomically disadvantaged older adults experiencing a digital divide need help to access information and communication technologies through a fee waiver or subsidy to cover internet equipment and subscription and ensure continuous connectivity. Older adults with VI who do not know how to use the internet/HIT but want to learn should be provided instruction, with special attention to accessibility features and adaptive devices. Older adults with a low income also need better access to preventive eye care and treatment of VI as well as other health care services.
Assessing the Credibility and Authenticity of Social Media Content for Applications in Health Communication: Scoping Review (Preprint)
Authors: Jenkins Eva L , Ilicic Jasmina , Barklamb Amy M , McCaffrey Tracy A
Published: December 2019

BACKGROUND

Nutrition science is currently facing issues regarding the public’s perception of its credibility, with social media (SM) influencers increasingly becoming a key source for nutrition-related information with high engagement rates. Source credibility and, to an extent, authenticity have been widely studied in marketing and communications but have not yet been considered in the context of nutrition or health communication. Thus, an investigation into the factors that impact perceived source and message credibility and authenticity is of interest to inform health communication on SM.

OBJECTIVE

This study aims to explore the factors that impact message and source credibility (which includes trustworthiness and expertise) or authenticity judgments on SM platforms to better inform nutrition science SM communication best practices.

METHODS

A total of 6 databases across a variety of disciplines were searched in March 2019. The inclusion criteria were experimental studies, studies focusing on microblogs, studies focusing on healthy adult populations, and studies focusing on either source credibility or authenticity. Exclusion criteria were studies involving participants aged under 18 years and clinical populations, gray literature, blogs, WeChat conversations, web-based reviews, non-English papers, and studies not involving participants’ perceptions.

RESULTS

Overall, 22 eligible papers were included, giving a total of 25 research studies. Among these studies, Facebook and Twitter were the most common SM platforms investigated. The most effective communication style differed depending on the SM platform. Factors reported to impact credibility included language used online, expertise heuristics, and bandwagon heuristics. No papers were found that assessed authenticity.

CONCLUSIONS

Credibility and authenticity are important concepts studied extensively in the marketing and communications disciplines; however, further research is required in a health context. Instagram is a less-researched platform in comparison with Facebook and Twitter.
Vs30 Mapping and Soil Classification in The Southern Part of Kulon Progo Using Rayleigh Wave Ellipticity Inversion
Authors: Sunardi Bambang
Published: December 2019

Shear wave velocity from the ground surface to a depth of 30 meters (Vs30) is a parameter to determine dynamic characteristics of the soil, which can be used to assess the level of seismic hazard. Thus, Vs30 mapping has an important role in seismic hazard mitigation efforts. Vs30 can be determined by Multichannel Analysis of Surface Waves (MASW) and Spatial Autocorrelation (SPAC) methods. A simpler alternative can be done by using Rayleigh wave ellipticity. The main objective of this research is to map Vs30 in the southern part of Kulon Progo using Rayleigh wave ellipticity inversion. In this study, Rayleigh wave ellipticity inversion was performed on 42 microtremor single measurement data, scattered in the southern part of Kulon Progo. The inversion results are used to estimate the value of Vs30 and classify the soil type at the measurement points, referring to SNI 1726:2012. A Vs30 distribution map and soil type classification are obtained by applying the geostatistical interpolation method. The mapping result showed that most of the southern part of Kulon Progo has a relatively low Vs30 value. These values are in the range of 180-342 m/s, which categorized as stiff soil (SD). In this region, some parts located in the hilly and transition zones have relatively high shear wave velocities in the range of 357-578 m/s and included in the category of very dense soil/ soft rock (SC) types
Determination of Boiler Building Verticality in Power Plant Construction using Terrestrial Laser Scanner (TLS)
Authors: Setiawan Mohamad Bagas , Yulaikhah Yulaikhah , Andaru Ruli
Published: December 2019

Nowadays, Indonesian government is focusing on build up infrastructures, especially power plant infrastructures to fulfil electrical energy needs. One of the power plants that will be built up is Waai power plant which located on Waai village, Maluku Province. Waai power plant had been postponed since 2014. In order to build this power plant, the advisability of the building needed to be checked from its verticality level. This level was determined by Terrestrial Laser Scanner (TLS). The TLS’s point clouds were registered using two methods, there are target to target and cloud to cloud methods. There are 65 beams on the power plant boiler building, but only 31 beams that used as the samples to assign the verticality of the boiler construction. The verticality level was set on the X-axis, Y-axis, and the resultant of the X and Y axis by using Pythagoras theorem after the bottom and top coordinates from each beam was determined. The Queensland Building and Construction Admission Standards and Tolerances Guide 2016 was used as tolerance of verticality level. The result of the verticality calculation presented on the X-axis consisted from -0ᵒ 1’ 26,678” to 0ᵒ 4’ 11,778” with the average was 0ᵒ 1’ 40,820” and major direction pointed the positive axis. On the Y-axis, the average was -0ᵒ 0’ 45,772” with -0ᵒ 3’ 33,345” as minimum and 0ᵒ 1’ 25,319” as the maximum and the major direction went to the negative axis. The verticality on the resultant of X and Y axis was from 0ᵒ 0’ 45,225” until 0ᵒ 4’ 15,674” with the average was 0ᵒ 2’ 27,057” and the direction was to the southeast. After the verticality number was compared with the tolerance, the verticality level was smaller than the standard on each beam. From the result, we can conclude that the boiler building on the Waai power plant can be categorized safe to reconstruct.
Utilization of Tide Observation and Satellite Altimetry Data for Detecting Land Vertical Movement
Authors: Faridatunnisa Maritsa
Published: December 2019

Indonesia is one of the country that often experiences earthquakes and volcanic eruptions because of its position on the meeting point of three active tectonic plates, namely the Eurasian, Indo-Australian and Pacific plates. This causes movement or deformation both horizontally and / or vertically. Current movement monitoring is done using GNSS technology. However, the distribution of monitoring points are not spread evenly and the results of GNSS observation have weaknesses in their vertical components. An alternative method for monitoring movement especially in vertical components is using combination of tide observation and satellite altimetry data. The measurement concept of satellite altimetry produces absolute sea level values and its not affected by plate movements,besides tidal measurements which sensors are installed on the ground so that the sea level values are affected by land uplift or subsidence at that location. This study used main data, namely long-period tidal observation data and GDR (Geophysical Data Record) satellite altimetry. GNSS observation data is needed as a control of vertical movement. The differences in spatial and temporal resolution of tidal observation and satellite altimetry are overcome by two methods, namely the daily and monthly methods. Each of these methods will produce an annual SLR value (Sea Level Rise) from tidal data and satellite altimetry calculated using linear regression. The difference between the tidal and satellite altimetry data trends is compared with the vertical movement value from GNSS data. The results of the study indicate that the determination of vertical movement can be done using tidal observation and satellite altimetry data, especially using the monthly method. The trend of vertical movements of tidal observation and satellite altimetry data shows the same pattern with land vertical movement of GNSS data even though the value is different. Therefore, the method to determine vertical movement from hydrological data can be used as an initial observation on a coastal area regarding the phenomenon of vertical movements that occur in the area.
ASSESSMENT OF ANALGESIC ACTIVITY OF NELUMBO NUCIFERA FRUIT ETHANOL EXTRACT
Authors: RAJPUT MUHAMMAD ALI , ZEHRA TABASSUM , ALI FIZZAH , KUMAR GUNESH
Published: December 2019

Objective: Utilization of herbal remedies rich in flavonoids and vitamins have increased significantly these days to treat various disorders, thus existing research work encircled to appraise the analgesic effect of Nelumbo nucifera fruit (NNF) for evaluating its traditional use pharmacologically in disorders which are associated with pain and inflammation.

Methods: Central analgesic activity in mice was assessed by tail flick test and the latency time i.e. the removal of tail from the stimulus was recorded. Similarly acetic acid induced writhing test was also conducted for the assessment of peripheral analgesic effect in mice and number of writhes was counted along with percent inhibition of writhes.

Results: In tail flick test the peek anti-nociceptive effect at all doses of fruit was observed at 90 min. However, the percentage of tail elongation time was highest at a dose of 200 mg/kg i.e. 82% at 90 min. Number of writhes was highly significantly reduced at all doses of NNF but maximum effects were observed at dose 200 mg/kg as compared to control, indicating 48.41 % inhibition of writhes.

Conclusion: NNF have exhibited strong analgesic effect in both animal models, which may be connected with the synergistic actions of flavonoids, saponins and tannins on arachidonic acid pathway inhibition. Hence NNF seems to have a great potential in disorders associated with pain but more experimental trials in this field are required to confirm these findings.
Optimization study of shape of translational shell of square plan
Authors: Tupikova Evgeniya M.
Published: December 2019

The aim of the work. The static analysis and comparison of the results for translational shells under equally distributed load of dead weight are provided. The shells of the similar general dimensions in plan and rise of four different types: translation of catenary along catenary, circle along circle, ellipse along ellipse and sinusoid along sinusoid are investigated. Methods. The finite element method was applied for the analysis. The research was conducted for the shells of material of

reinforced concrete characteristics. Results. The comparison has shown that shells of catenary and circle translation surface demonstrate the most advantageous behavior under loading; the worst results for reinforced concrete were got for ellipse along ellipse translation shell. The peculiarities of each type behavior were revealed, that is of interest for their prospective reduction to practice of structural design.
Political reforms in Jordan following the events of the Arab Spring
Authors: Hawamdeh Mazen Hussien Faleh , Al-Qteishat Ahmad Saher Ahmad
Published: December 2019

Following the events of the Arab Spring and the popular protests that broke out in some countries in the Arab world in 2011, including Jordan, extended political reforms were carried out in Jordan, including major constitutional amendments and developments in political life, political parties and civil society institutions. The study aims to identify the reality of the political reform process in Jordan that took place after the events of the Arab Spring. The importance of the study stems from the depth of the eﬀects of the variables of this period on Jordan and its reform programs and its transformations towards democracy. The study aims to achieve the following objectives: To identify the nature of the factors and reasons that contributed to the outbreak of the current Arab revolutions, and identifying the reality of the process of political reform in Jordan before the events of the Arab Spring, and to study and analyze the political reforms in Jordan after the events of the Arab Spring.
Russian-Chinese cooperation in Central Asia in the context of ‘Belt and Road Initiative:’ Historical retrospective and economic prospects
Authors: Martynenko Stanislav E. , Parkhitko Nickolay P.
Published: December 2019

This article examines Russo-Chinese investment cooperation in China’s Belt and Road Initiative (originally the Silk Road Economic Belt). At the same time, it also studies bilateral agreements, as well as investment and mechanisms. Another focus is the impact of the BRI in Central Asian countries on Russian interests in the region. Research is based on an analysis of the history of joint Russian and Chinese initiatives for economic development to determine the feasibility of cooperation in the BRI. Meanwhile, the authors discuss the BRI’s impact on the economic and foreign policy of the two partners, as well as the risks and opportunities for Russia. The article is based on content and statistical analysis combined with a historical approach. It concludes that Russia and China are actively developing investment cooperation in the framework of the BRI, including the Silk Road Fund. The principal elements of the partnership involve the economy and processing and transporting energy resources. Its objective is to attain both regional economic stability as well as maximizing economic and political independence.