bluuebunny/crossref_metadata_2025 huggingface dataset:
SOSIALISASI PENGOLAHAN DAN PENANGANAN LIMBAH PADAT CAIR CV. PAWON IBUN
Authors: Faiq Fawwaz Muhammad , Soraya Santi Sintha , Edra Nugraha Reva , Aini Fauziyah Nur
Published: August 2024

CV. Pawon Ibun adalah produsen makanan sehat untuk bayi sebagai makanan pendamping asi. Produksi ma kanan, tidak terlepas dari apa yang dinamakan limbah. Limbah industri batik terdiri atas limbah cair, limbah padat dan limbah gas. Pengelolaan limbah yang kurang baik akan mengakibatkan pencemaran lingkungan dan bisa merusak ekosistem sekitarnya. Oleh karenanya perlu dilakukan sosialisasi pengelolaan limbah terhadap para pegawai CV. Pawon Ibun dengan narasumber dari mahasiswa UPN “Veteran” Jawa Timur. Metode pelaksanaan dilakukan dengan paparan materi dan diskusi aktif dengan para peserta sosialisasi. Penanganan limbah bisa dilakukan melalui tahapan proses yaitu proses Kimia, proses Fisika dan proses Biologi. Pengolahan limbah cair minyak, dapat digunakan Grease Trap sebagai reaktor pengolahan limbah. Sosialisasi ini dijelaskan terkait jenis jenis grease trap, dan grease trap yang cocok untuk digunakan oleh CV Pawon Ibun. Grease trap yang cocok digunakan oleh CV. Pawon Ibun adalah grease trap portable. Setelah pemaparan materi, kegiatan ditutup para peserta melakukan diskusi intens oleh pemateri.
ANALISIS PH, KESADAHAN DAN TDS PADA UMPAN AIR BOILER TERHADAP KOROSIFITAS INDUSTRI PABRIK TAHU TIGA SAUDARA DI DESA BOCEK
Authors: Wahyuningsih Indah Dwi , Susianto Mordekhai Yosep , Ridha Silviya Nur , Fauzan Hilmy .R.S Rionaldo , Permaji Aditya Putra , Pujiastuti Caecilia , Wahyusi Kindriari Nurma
Published: August 2024

Desa Bocek terletak di Kecamatan Karang Ploso, Kabupaten Malang. Desa ini memiliki banyak sekali industri pengolahan tahu. Pabrik Tahu Tiga Saudara ini adalah badan usaha swasta yang termasuk dalam usaha pengolahan tahu. Dalam pengolahan tahu tersebut memerlukan air dalam pembuatannya. Secara kimiawi air harus memenuhi persyaratan sehingga tidak terdapat zat kimia salah satunya kesadahan berupa CaCO3. Proses pembuatan pengolahan tahu di suatu industri memerlukan boiler sebagai peran penting dalam pengolahan tersebut. Sumber air yang dipakai dalam boiler ini sangat berpengaruh terhadap steam yang dihasilkan dari boiler tersebut serta untuk menghindari terjadi korosi pada aliran pada boiler. Oleh karena itu, perlunya dilakukan pengecekan suatu kandungan yang terkandung dalam air sumur tersebut agar menghindari penurunan fungsi pada boiler yang dipakai jika digunakan berkepanjangan dengan menjaga nilai pH dan kesadahan dengan melalui uji pH dan TDS yang akan dilakukan oleh mahasiswa Bina Desa Teknik Kimia UPN Veteran Jawa Timur. Berdasarkan hasil pengujian dapat ditarik kesimpulan air yang digunakan untuk pengolahan air di Industri Pabrik Tahu Tiga Saudara memenuhi standar kualitas air, dengan hasil TDS air sebesar 192 mg/L, kesadahan sebesar 144 mg/L dan pH sebesar 7. Oleh karena itu, pengolahan yang digunakan tidak berdampak negatif pada kesehatan warga sekitar dan tidak menyebabkan korosifitas pada alat boiler yang dapat mengurangi fungsi boiler
Diskursus Sosial Stakeholder dalam Upaya Pelestarian Sumber Daya Alam (UPSA) di Kabupaten Malang
Authors: Muttaqin Tatag , Sukmawati Musdzalifah , Bala Imam Ade Putra , Pradipta Naresvara Nircela
Published: August 2024

UPSA (The Natural Resources Conservation Effort is one of BPDAS Brantas Sampean’s RHL (Forest and Land Rehabilitation) progams which are carried out in 3 places namely Pujon Hill, UB Forest and Wajak, Malang Regency. Collaboration between stakeholder is the main key to the succes of policy produts and their sustainability. Discourse is present as a tool that is able to provide an explanation of sosial conditions. Aim of this research is how the perspectiveof stakeholder influences the follow-up action pf the progam.  Data collection uses observation, interviews document analysis related to UPSA. Discourses analysis begins with the result of interviews that have been recorded and then transcribed into writing and data analysis by the Nvivo12 software. The result of the data re then explained descriptively. Our findings show that the perspective of each stakeholder towards the UPSA Progam Influences land management. The Occurrence of domination of power, a sense of ownership and openness among stakeholders has the potential to create new conflicts.
Keywords : Social Discourse, Stakeholder, UPSA
Pembuatan Mikroemulsi Minyak Buah Merah (Pandanus conoideus) dan Penentuan Kadar Total Fenol
Authors: Rosiyati Mei
Published: August 2024

Buah merah merupakan tanaman khas dari papua yang dimanfaatkan sebagai bahan baku pembuatan makanan, minuman, dan obat tradisional oleh masyarakat papua. Buah merah kaya akan senyawa bioaktif, seperti vitamin dan mineral, serta senyawa antioksidan seperti flavonoid dan fenolat. Penelitian ini bertujuan untuk mengetahui kadar fenol total mikroemulsi minyak buah merah dengan konsentrasi surfaktan 20%, 30%,dan 40%. Metode: yang digunakan dalam penelitian ini yaitu Folin-Ciocalteu, metode ini didasarkan pada oksidasi senyawa fenol oleh reagen Folin-Ciocalteu, yang menghasilkan warna biru. Tujuan: Pembuatan mikroemulsi minyak buah merah dengan perbedaan konsentrasi surfaktan 20%, 30%, dan 40%. Mikroemulsi buah merah kemudian dilakukan proses analisis kualitatif meliputi uji identifikasi senyawa fenol dan  analisis kuantitatif dengan metode spektrofotomoteri UV-Vis. Hasil dan Kesimpulan: berdasarkan hasil uji kualitatif mikroemulsi minyak buah merah dengan konsentrasi surfaktan berbeda 20%, 30%, 40% menunjukkan semua sampel memiliki kandungan senyawa fenol. Kemudian untuk hasil uji kuantitatif menunjukkan kadar total fenol yang diperoleh secara berturut-turut yaitu 1,274%, 2,902%, 2,902%.Kata Kunci: Buah Merah Papua, Fenol Total, Mikroemulsi, Spektrofotometri UV-Vis
Pembinaan Keamanan Pangan Industri Rumah Tangga Pangan (IRTP) Guna Percepatan Mendapatkan Izin Edar Di Wilayah Kota Bengkulu Tahun 2022
Authors: Pravita sari Ayu
Published: August 2024

Industri Rumah Tangga Pangan yang selanjutnya disingkat IRTP adalah industri  pangan yang memiliki tempat usaha di tempat tinggal dengan peralatan pengolahan pangan manual hingga semi otomatis. Industri Rumah Tangga Pangan (IRTP) dapat memproduksi pangan olahan yang dihasilkan. Pangan Produksi IRTP adalah pangan olahan hasil produksi IRTP yang diedarkan dalam kemasan eceran dan berlabel. Untuk pemasaran produk, maka IRTP harus memiliki Sertifikat Produksi Pangan Industri Rumah Tangga  (SPP-IRT). Terdapat 20 IRTP yang belum memiliki Sertifikat. Sertifikat ini akan dikeluarkan oleh Dinas Kesehatan dan diproleh setelah pemilik IRTP mendapatkan pelatihan mengenai keamanan Pangan. Kegiatan pengabdian masyarakat ini akan memfasilitasi pelatihan keamanan Pangan. Dengan adanya kegiatan pengabdian masyarakat ini, seluruh pemilik IRTP yang berjumlah 20 peserta telah memiliki Sertifikat Produksi Pangan Industri Rumah Tangga  (SPP-IRT). Hasil menunjukkan bahwa ada peningkatan pengetahuan secara signifikan sebelum dan sesudah diberikan pelatihan.
HUBUNGAN KELEMBABAN DAN KEBIASAAN MEROKOK PENGHUNI DI DALAM RUMAH DENGAN PENYAKIT ISPA PADA BALITA
Authors: Ullya  , Sari Rosdiana Sefti Eka
Published: August 2024

Acute Respiratory Infection (ARI) is a global concern because it is one of the main causes of death in children under five years old (toddlers) in the world. In Indonesia ARI cases always rank first in the cause of infant mortality. In addition, ARI is often on the list of the ten most afflicted diseases in hospitals and health centers. Based on the profile of Bengkulu Province Health in 2017, as for the 10 highest diseases based on the illness data of the ISPA puskesmas occupy the first position. Several factors such as humidity in the house and occupant smoking habits in the house are thought to be risk factors for the occurrence of ARI disease. The purpose of this study was to determine the relationship of humidity and smoking habits of residents in homes with ARI disease in Kelurahan Kebun Kenanga, Bengkulu City. Crossectional research design with 124 samples. The research instrument used was moisture measurement with thermohygrometer and questionnaire. Data analysis was done by univariate and bivariate using the chi square test with a value of pvalue <0.05. The results of this study indicate that there is a relationship between humidity and ARI disease (pvalue =0.007), and indicates that there is a relationship between occupants' smoking habits in homes with ARI disease (pvalue = 0.021). The results of the univariate analysis, most (68%) had moisture did not meet the requirements, most (69%) respondents smoked inside the house. most (31%) toddlers experience moderate ISPA pain, the community, especially the respondents in this study pay more attention to what can affect the occurrence of ARI disease or that can worsen the condition of infants affected by ARI.
Physico-mechanical Characteristics of the Diaphragms of a Diaphragm Piston Pump Made of Polyurethane Compound
Authors:   FGBNU FNATS VIM, Kataev Yu.V.
Published: August 2024

The results of the bench tests of the diaphragms of diaphragm piston pumps made of composite materials based on twocomponent polyurethane filled with basalt fiber are presented. The tests were carried out using a tensile testing machine equipped with special equipment that allows simulating a complex stress-strain state in the diaphragm which is characteristic of pump operation in the real conditions. According to the results of the tests the diaphragms with a basalt content of 1 and 2 vol. % showed the greatest resistance to mechanical loads.
How to Achieve Further Progress of Journal of Korean Neurosurgical Society (JKNS) - Improve the Impact Factor (IF) and Maintain It Continuously
Authors: Yang Hee-Jin
Published: August 2024

Journal of Korean Neurosurgical Society (JKNS), which has a history of over 50 years, has made great progress recently. In order to continue this progress in the future, we need to think about the strategies we will take and put them into practice. The progress of JKNS is an important opportunity to publicize the achievements of Korean neurosurgery to the world and for Korea to contribute further to global neurosurgery. We also need to think about and implement various measures to improve the inflow of papers of high quality from various countries and to establish an appropriate merit system for reviewers.
Higher Order Aberrations in Patients with Unilateral Nasolacrimal Duct Obstruction
Authors: Sönmez Melek Mutlu , Elibol Emine Savran , Sali Fatma , Oğuz Halit
Published: August 2024

Purpose: To compare corneal higher order aberrations (HOAs) in patients with epiphora caused by unilateral primary acquired nasolacrimal duct obstruction (PANDO) and their fellow eyes.Methods: A total of 122 eyes of 61 patients with unilateral PANDO were included. Affected eyes were named as group 1 and contralateral eyes as group 2. The Munk score and fluorescein dye disappearance test (FDDT) were assessed. Corneal topographic and HOAs measurements were taken by Sirius topography.Results: There were 47 female and 14 male patients. The mean keratometry was 43.84 ± 1.4 in group 1 and 43.96 ± 1.4 in group 2 (p = 0.73). The mean corneal topographic astigmatism was 0.81 ± 0.7 in group 1 and 0.78 ± 0.5 in group 2 (p = 0.57). The mean coma-like aberration was 0.19 ± 0.2 in group 1 and 0.10 ± 0.1 in group 2 (p = 0.03). The mean spherical-like aberration was 0.16 ± 0.1 in group 1 and 0.11 ± 0.1 in group 2 (p = 0.04). The mean total corneal HOA was 0.30 ± 0.5 in group 1 and 0.23 ± 0.2 in group 2 (p = 0.04). The mean Munk score was 3.47 ± 1.0 in group 1. There was a positive correlation between the Munk score and both coma-like aberration (r = 0.53, p = 0.003) and total corneal HOAs (r = 0.44, p = 0.010). The mean FDDT grade was 2.60 ± 0.1 in group 1. A positive correlation was observed between the FDDT grade and both coma-like aberration (r = 0.48, p = 0.001) and total corneal HOAs (r = 0.33, p = 0.001).Conclusions: Epiphora in patients with PANDO can affect corneal HOAs. As patients’ symptoms and tear pooling were increased as corneal HOA levels increased.
Effects of Upper Eyelid Blepharoplasty on Perceived Attractiveness, Success, and Health
Authors: Sönmez Melek Mutlu , Solmaz Iskender Alkın , Ertan Elif
Published: August 2024

Purpose: This study aims to evaluate the impact of upper eyelid blepharoplasty on perceived age, attractiveness, success, and overall health as rated by observers.Methods: A web-based survey was conducted with 203 observers who were unaware of the study’s purpose. They assessed preoperative and postoperative images of 12 female patients using the Delphi method to ensure appropriate image selection and unbiased ratings. Observers rated the images on a visual analog scale from 0 to 10, where higher scores indicated more favorable perceptions.Results: The observer group consisted of 108 women (53.2%) and 95 men (46.8%), with an age range of 18 to 61 years. The mean age perceived by observers decreased from 51.75 years before surgery to 42.10 years after surgery, indicating a significant reduction in perceived age (p = 0.01). Additionally, postsurgical assessments showed significant increases in perceived attractiveness, success, and overall health.Conclusions: Upper eyelid blepharoplasty significantly enhances how patients are perceived in terms of youthfulness, attractiveness, and success. These findings underscore the positive impact of cosmetic eyelid surgery on public perception.
Metode Penugasan Membaca Dalam Al-Quran Surat Al-Alaq 1-5
Authors: Ma'sum Ali , Hafidhuddin Didin , Alim Akhmad
Published: August 2024

Tujuan penelitian ini adalah untuk mengkaji perintah membaca dalam surat Al- Alaq 1-5 sebagai metode penugasan membaca dalam pembelajaran. Penelitian ini adalah penelitian kualitatif, yang bersifat studi pustaka. Data penelitian dianalisis dengan metode analisis isi. Dari hasil penelitian didapati bahwa tujuan dari penugasan membaca hendaknya bukan hanya sekedar mengembangkan potensi intelektual semata namun harus berorientasi kepada penguatan nilai-nilai ketauhidan. Adapun untuk objek bacaan dalam penugasan membaca hendaknya tidak terbatas pada teks tertulis seperti buku saja. Objek bacaan dapat berupa fenomena atau proses kejadian dan pertumbuhan. Selain itu, penugasan membaca hendaknya diberikan secara berulang-ulang agar siswa mendapati pemahaman dan penguatan makna dari apa yang dibaca. Dari penugasan membaca yang berdasarkan pada surat Al-Alaq 1-5 diharapkan akan mengantarkan siswa kepada ilmu pengetahuan dan menjadikan mereka patuh dan tunduk kepada Allah.
On being different
Authors:   , Şahin Onur
Published: August 2024

In this dissertation, I investigate how being different from the majority of one’s colleagues shapes social inclusion perceptions at work. In Chapter 1, I introduce the relational demography approach and ingroup projection model as the frameworks of my dissertation and summarize the methods, findings, and broader implications of the empirical chapters that follow. In these chapters, I utilize a multi-method approach consisting of desk research, experimental studies, and large-scale correlational studies to offer six significant contributions to the literature. First, in Chapter 2, an analysis of diversity statements of 84 Dutch private and public organizations showed that most statements include both surface-level (readily visible, such as gender and ethnicity) and deep-level dimensions (more underlying, such as personality and sexual orientation). However, surface-level dimensions were more often included, without clear differences between statements of private and public organizations. Second, in Chapter 3, experimental studies (N = 128 in Study 1; N = 196 in Study 2, recruited via Prolific) established the causal relationship between dissimilarity and social inclusion. Third, in Chapter 4, a survey study with 887 employees of a public organization in the Netherlands revealed that deep-level dissimilarity, rather than surface-level dissimilarity, related to social inclusion and that inclusion explained the relationships between dissimilarity and work-related outcomes. Fourth, in Chapter 5, a survey study with 6,312 employees of another Dutch public organization accounted for multidimensionality and revealed that as employees perceived dissimilarity on more dimensions, they perceived less inclusion. Furthermore, the results showed that dissimilarity in personality, ethnicity/cultural background, age, level of education, work experience, and disability negatively related to perceptions of inclusion, offering a more nuanced understanding of the dissimilarity-inclusion relationship. Fifth, a review of the relational demography literature in Chapter 6 identified four general mechanisms theorized to explain why dissimilarity relates to outcomes: 1) uncertainty, 2) trust, 3) disapproval, and 4) initiated interaction between colleagues. A survey study with 2,409 UK residents (recruited via Prolific) confirmed that all four mechanisms uniquely explained the dissimilarity-inclusion relationship. Sixth, and finally, I found support for the indispensable role of the organizational climate for inclusion across Chapters 4, 5 and 6. In these chapters, a positive climate for inclusion buffered the negative relationships between dissimilarity and outcomes. My research argues for a broader consideration of dissimilarity dimensions beyond the dimensions diversity policies typically focus on, emphasizing the importance of recognizing multidimensionality and the crucial contextual role of climate for inclusion. This dissertation not only enriches our understanding of workplace diversity, but also offers actionable opportunities to mitigate social inclusion disparities.
Open-Ended Approach for Critical Thinking Skills in Mathematics Education: A Meta-Analysis
Authors: Yuni Fitriyah  , Wahyudin  , Suhendra  , Hanifah Nurhayati  , Tri Sedya Febrianti
Published: August 2024

There have been numerous research on developing students’ critical thinking skills through an open-ended approach in mathematics education show conflicting results. Some research results implied a strong effect; others range from moderate to modest effect. This research aims to summarize and predict the implementation of an open-ended approach to critical thinking skills in mathematics education over the last five years. This research utilized a meta-analysis using the PICOS (Population, Interventions, Comparator, Outcomes, and Study Design) approach. The sample used in this research is studies published in the form of articles and proceedings as well as theses and dissertations. The databases are sourced from Google Scholar, Crossref, and Semantic Science using the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) method, which includes 14 primary studies found during 2018-2023 in Indonesia. The results are the implementations of an open-ended approach to improve critical thinking skills in mathematics education, show an average of 1.44, which is included in the high category. Factors that influence the heterogeneity of effect sizes are study characteristics, such as sample size, year of publication, level of education, demographics, and publication type. The characteristics of the research that results in a large effect size value are an open-ended approach implemented in elementary schools, studies with a sample size of more than 30, studies that are published in 2018 and in journals, and implementation of the approach in regencies.
STEM based Project Learning: How It Affects Preservice Science Teacher’s Creativity Before, During, and After Pandemic Covid-19?
Authors: Nurramadhani Annisa , Riandi  , Permanasari Anna , Suwarma Irma Rahma
Published: August 2024

Creativity Are the important skills to face the globalization in this era. Students, especially preservice teacher should have these useful skills for make next generation are more creative, struggling with the competition between human and computers, struggling with the world condition during and after pandemic strikes, and well prepared for their work field. Some of the learning approaches have been applied in the courses to construct their creativity, one of them, are STEM (Science, Technology, Engineering, and Mathematics) by the project.  This research’s aim is to investigate how is preservice science teacher’s creativity by the STEM based project learning before, during, and after pandemic covid-19. The method that is used is qualitative research by using class observation and quantitively count by creativity rubrics that includes creative thinking, behaviour, and products. This research is conducted in SETS learning (2nd semester in every year) by using STEM based project from the students of science preservice teacher year 2019, 2020, 2021, 2022. STEM based project learning could improve preservice science teacher’s creativity but it has differences for each class. Class 2019 has outperformed for creativity among others. While, class 2022 has less performed for creativity among others. Based on the observation, the covid-19 outbreak has high influence to this result because of the way of their learning in their high school before. Full online learning makes the biggest impact to science preservice teacher’s creativity during covid-19 outbreak.
The Influence of Bullying Experiences on Mathematics Curiosity in Prospective Mathematics Teachers
Authors: Rizka Kamalia Agustin  , Rizqona Maharani
Published: August 2024

Di era saat ini, bullying semakin banyak terjadi khususnya pada pelajar. Bullying merupakan suatu tindakan menyakiti orang lain yang dapat menimbulkan trauma mental dan psikologis. Dalam hal ini, siswa perlu meminimalisir perundungan agar dapat menanamkan rasa ingin tahu ketika belajar matematika. Rasa ingin tahu matematis dalam pembelajaran matematika merupakan sikap positif yang berpengaruh terhadap keberhasilan pencapaian tujuan pembelajaran matematika. Penelitian ini bertujuan untuk mengetahui pengaruh pengalaman bullying siswa terhadap rasa ingin tahu matematika di IAIN Kudus. Penelitian ini termasuk penelitian korelasional. Sampel penelitian diambil dengan menggunakan teknik cluster random sampling dan diperoleh dua kelas siswa jurusan matematika berjumlah 40 siswa. Analisis data dalam penelitian ini menggunakan Uji Regresi Linier sederhana. Hasil penelitian menunjukkan terdapat hubungan negatif dan signifikan antara pengalaman bullying dengan rasa ingin tahu matematika pada calon guru matematika. Rasa ingin tahu terhadap matematika menjadi salah satu faktor yang mencegah calon guru matematika mengalami bullying.
Preleminary Study: Need Analysis for Research and Development of Automatic Sprinkling System based on Arduino and Soil Moisture Sensor as The Instructional Aids in Soil Moisture Measurement
Authors: Masta Ngia , Yonas Ferdinal Silaban
Published: August 2024

Instructional aids will made student easier to understanding and applying physics concepts.  This study aims to obtain data and analyze the student’s needs toward to the instructional ais soil moisture measurement in physics lesson. Samples in study were student of 33 peoples, taken from class XH at SMAN 71 Jakarta with technique purposive sampling. This study resulted: physics learning motivation of student are in the medium category, with attention 87.88%, relevance 55.30%, confidence 60.61% and satisfaction 87.12%. Curriculum analysis show in class X, measurement lesson still can be developed to soil moisture measurement based on contextual learning approach. Based on style learning, 4,48% students who have visual learning style, auditory 24.24% and kinesthetic 27.27%. A total of 59.85% students experience difficulty in learning physics. As many as 79.55% of students agree that hands on method in learning can reduce difficulty in learning physics. As many as 87.12% of students agree that they need automated instrument in physics practice and only 39.39% of students has known about Arduino. The frequently used learning media in class were on audio-visual category, starting from power point slide presentation, Canva’s slides presentation, video, simulation and animation. All of those findings were supported research and development of oto-sprinkler system by using humidity sensor and Arduino Uno. Result of this study will become the base contextual in developing contextual teaching aids in form of soil moisture measurement, so that can increase the physics learning motivation in student.
Didactic Intralingual Dubbing of Vertical Videos for EFL Learners
Authors: Elejalde Aitziber
Published: August 2024

This paper is focused on the development of a didactic proposal for English students in the Basque Country. Specifically for students in the 1st year of Bachillerato with Spanish and Basque as their L1 and English as their L2 which aims to improve their communication skills, especially oral abilities and pronunciation, through the use of didactic dubbing. This proposal is framed within a project-based learning (PBL), in which the final project is the creation of a vertical video dubbed in English. For this purpose, six sessions have been designed with different group activities that will culminate with the presentation of the video. This didactic unit revolves around social networks and seeks to meet the requirements of current regulations in terms of objectives, contents, competences and evaluation criteria. In addition, transversal elements such as the appropriate use of social networks, fears or interpersonal relationships are worked on. The use of videos in vertical format meets the increasing demand for creating content in this format that adapts to the new mobile devices.
A New Textbook Design in Language Teaching: Plurimethodological Pair-unit
Authors: Acar Ahmet
Published: August 2024

In this paper, I propose a model of plurimethodological approach in ELT textbook design, in which one unit is based on the communicative PPP unit model, where the unit ends with a final communicative task, and the following unit is based on the action-oriented unit model, where the unit is a mini-project unit as a whole. Such a textbook model is based on the concept of plurimethodological pair-unit, where the communicative approach and the action-oriented approach are combined in coherence and synergy. In such a plurimethodological textbook design, the topics of the two successive units (one PPP unit and the other mini-project unit) are the same or closely related, so that the unit based on the PPP model will provide the students with much of the language and documentary resources needed to complete the mini-project in the following unit. The mini-project unit will provide the students with additional language and documentary resources for carrying out the mini-project, but as there will be less language and documentary work for students in this unit, students will be better able to concentrate on carrying out the mini-project.
Biomimetic 3D-printed Composites: Ballistic Impact Resistance with Nacre-Inspired and Tubulane Structures
Authors: Sacherich Adam B. , Sanei Seyed Hamid Reza , Bakis Charles E.
Published: August 2024

This research delves into nature-inspired designs for creating materials with exceptional impact resistance, leveraging cutting-edge 3D printing techniques. Our composite design features a nacre-like outer layer combined with a tubulane-resembling core, aiming to enhance energy dissipation significantly. By emulating the dense aragonite structure found in natural nacre and the unique porosity of tubulane, to enhance ballistic impact resistance. To validate its effectiveness, we conducted ballistics tests using a 40-grain lead-tipped .22 LR bullet at an initial velocity of 330.7 m/s, with a specialized chronograph setup to measure both initial and post-penetration bullet velocities, quantifying energy absorption precisely. This study opens new frontiers in aviation safety, structural engineering, and personal protective equipment, showcasing the transformative potential of biomimicry and additive manufacturing in advancing public safety and material science.
IMPLEMENTASI PROGRAM JEMPUT BOLA LAYANAN e-KTP DI DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KABUPATEN BUTON TENGAH PROVINSI SULAWESI TENGGARA
Authors: Kasih Putri Bunga , Harsanti Hagia
Published: August 2024

Kartu Tanda Penduduk elektronik (e-KTP) adalah salah satu dokumen penting yang dimiliki seseorang dan bukti sah bahwa seseorang penduduk telah terdaftar sebagai penduduk di wilayah tertentu dan berhak mendapatkan fasilitas pelayanan publik dari pemerintah. Akan tetapi, kurangnya kesadaran masyarakat Kabupaten Buton Tengah dalam kepemilikan e-KTP serta akses jarak menuju kantor yang sangat jauh dan susah ditempuh mengakibatkan banyak masyarakat yang belum memiliki e-KTP . Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan implementasi program Jemput Bola layanan e-KTP di Dinas Kependudukan dan Pencatatan Sipil Kabupaten Buton Tengah. Penelitian ini menggunakan metode kualitatif deskriptif. Teknik pengumpulan data melalui wawancara, observasi, dan dokumentasi. Teknik analisis data meliputi mereduksi data, menyajikan data dan menarik kesimpulan. Edward III dalam teori Agustino digunakan sebagai dasar analisis. Teori ini menguraikan empat dimensi implementasi: Komunikasi, Sumber Daya, Disposisi, dan Struktur Birokrasi. Kesimpulan yang dilihat dalam penelitian ini berdasarkan dari 4 dimensi yang penulis gunakan yaitu hampir keempat dimensi tersebut dapat dikatakan berhasil. Meskipun pada dimensi Komunikasi belum berjalan dengan baik. Namun tiga dimensi lainnya sudah berjalan baik.
Kata kunci: Implementasi, layanan e-KTP, Program Jemput Bola
Kontrol tegangan pada terminal generator menggunakan AVR berbasis neural network
Authors: Sartika Linda , Prasetia Abdul Muis , Ramadhan Sudirman Fitri
Published: August 2024

Generator sinkron mempunyai permasalahan yaitu Ketidak stabilan tegangan pada generator sinkron menyebabkan sistem secara keseluruhan terutama kualitas sistem, kemampuan transfer daya dari pembangkit ke konsumen, kondisi terparah terjadinya mekanisme pelepasan beban dengan demikian maka diperlukan peralatan yang dapat mengendalikan kestabilan tegangan generator sinkron yaitu Automatic Voltage Regulator (AVR).  AVR adalah suatu perangkat yang dipasang pada generator yang dapat bekerja secara otomatis mengatur tegangan yang dihasilkan oleh generator agar tetap stabil. Penelitian ini mengontrol tegangan generator agar stabil menggunakan metode Neural Network (NN). Data penelitian NN diambil dari input dan output kendali PID dengan Sistem AVR yang sama. AVR sederhana dengan respon delay time  rise time , peak time  settling time , max overshoot dan untuk error steady state . AVR sederhana respon tidak terdapat overshoot dan respon waktunya lebih lambat 5,039s, konvensional terdapat overshoot yang tinggi dan lebih cepat 0,715s, NN respon yang didapatkan overshoot pada waktu 2,456s dan adanya usaha perbaikan respon tegangan kembali ke Vref
 
ABSTRACT
Synchronous generators have problems with the instability of the voltage, causing the system as a whole, especially the quality of the system and the ability to transfer power from the generator to the consumer, the worst condition is load shedding. Therefore, equipment is required to control the voltage stability of the synchronous generator with the automatic voltage regulator (AVR). AVR is installed on a generator to work automatically to regulate the voltage so that is remains stable. The generator voltage can be stably controlled using the neural network (NN) method. NN training data is obtained from the input and output of PID control with the exact AVR system. Simple AVR with response delay time  rise time , peak time  settling time  max overshoot and error steady state . Simple AVR response has no overshoot, and the response time is slower at 5,039s, conventional has a high overshoot and is faster at 0,715s. NN response obtains overshoot at 2,456s, and there is an effort to improve the voltage response to Vref.
Hubungan Kadar Kolestrol Dalam Darah Dengan Tingkat Nyeri Kepala Pada Penderita Hipertensi di Desa Keramat Kecamatan Martapura Timur
Authors: Suwandewi Alit , Mira Mira , Daud Izma , Khalilati Noor , Aprillia Hanura , Prisilia Ni Kadek Neviska
Published: August 2024

Latar Belakang: Penyakit tidak menular masih menjadi persoalan yang serius di Indonesia maupun dunia. Salah satu penayakit tidak menular ialah hipertensi, hipertensi terjadi karena penyempitan pembuluh darah akibat beberapa faktor salah satunya tertumpuknya lemak kolesterol yang berlebih. Hipertensi tidak jarang menimbulkan gejala khas seperti nyeri kepala.
Tujuan: Untuk mengetahui hubungan kadar kolesterol dalam darah dengan tingkat nyeri kepala pada penderita hipertensi Di Desa Keramat Kecamatan Martapura Timur.
Metode: Teknik pengambilan sampel menggunakan nonprobability sampling dengan metode total sampling yang melibatkan 57 responden penderita hipertensi Di Desa Keramat Kecamatan Martapura Timur. Penelitian ini menggunakan instrumen lembar pengukuran dengan menggunakan uji analisis spearman rank.
Hasil: Penelitian menunjukan bahwa kadar kolesterol responden paling banyak masuk dalam golongan batas tinggi (200-239mg/dL) sebanyak 36 responden (63,2%) dan tingkat nyeri kepala paling banyak masuk dalam kategori nyeri sedang (4-6) sebanyak 26 responden (45,61%), analisis uji spearman rank menunjukan hasil p value= 0,000.
Kesimpulan: Ada hubungan antara kadar kolesterol dalam darah dengan tingkat nyeri kepala pada penderita hipertensi Di Desa Keramat Kecamatan Martapura Timur.
Chromatographic Profiles and Determination of Total Flavonoid Content of the Ethyl Acetate Fraction of Kalangkala Leaves (Litsea Angulata Blum) Using Uv-Vis Spectrophotometry
Authors: Mardlatillah Mardlatillah , Rohama Rohama , Kurniawati Darini
Published: August 2024

Background: Kalangkala is a fruit plant typical of Kalimantan and belongs to the species of the genus Litsea which is thought to have potential as a natural antioxidant. Empirically, some people in South Kalimantan use the kalangkala plant, especially the seeds of the fruit, to treat boils. One of the compounds that have antioxidant and antibacterial content is flavonoids.Objectives: To determine the thin layer chromatography profile of the total flavonoid compound of the ethyl acetate fraction and to calculate the total flavonoid content of the ethyl acetate fraction of the leaf extract of Kalangkala (Litsea angulata Blum).Method: Thin Layer Chromatography Profile and Determination of Total Flavonoid Content of the Ethyl Acetate Fraction of Kalangkala Leaf Extract using the UV-Vis Spectrophotometry method. The data were then analyzed qualitatively and quantitatively.Results: The chromatographic profile of the total flavonoids of the ethyl acetate fraction of Kalangkala leaf eluent that was most optimal was Ethyl acetate : n-Hexane (3:7) because it showed the most stains, namely 5 stains. And in the uv-vis spectrophotometry method, the total flavonoid content of the ethyl acetate fraction of Kalangkala leaves (Litsea angulata Blum) was 0.9 mg QE/g.Conclusion: Kalangkala leaf extract on the TLC profile using ethyl acetate : n-Hexane (3:7) showed a total of 5 stains. And the value of the total flavonoid content of the ethyl acetate fraction of kalangkala leaves was 0.9 mg QE/g.
Formulasi Dan Evaluasi Fisik Sediaan Deodoran Gel Kombinasi Ekstrak Kulit Jeruk, Teh Hijau Dan Buah Pepaya
Authors: Nugraha Zen Achmad Redho , Budi Setia , Yusri Yusri
Published: August 2024

Ekstrak kulit jeruk memiliki aktivitas antibakteri, ekstrak the hijau memiliki aktivitas antiperspirant dan ekstrak papaya memiliki aktivitas sebagai pencerah pada kulit sehingga dikombinasikanlah ketiga ekstrak tersebut dan dibuat sediaan deodoran gel, deodoran gel diharapkan dapat memberikan rasa dingin serta cepat dalam pengaplikasiannya. Dasar konsentrasi carbomer yang digunakan pada penelitian ini yaitu 0,5%-2%. Tujuan penelitian ini yaitu Mendapatkan formulasi deodoran dengan zat aktif tumbuhan serta mendapatkan optimalisasi formulasi dan melihat evaluasi fisik pada sediaan deodoran gel kombinasi ekstrak kulit jeruk, the hijau dan buah papaya. Metode yang digunakan adalah pre-eksperimental one case shot study. Sediaan deodoran gel kombinasi ekstrak kulit jeruk, teh hijau dan buah papaya dibuat menjadi tiga formulasi dengan variasi gelling agent yang berbeda, pada formulasi I menggunakan carbomer (0,5%), formulasi II menggunakan carbomer (1,5%) dan formulasi III menggunakan carbomer (2%). Uji organoleptis dan uji homogenitas sudah memenuhi persyaratan. Pada uji pH didapatkan ketiga formulasi sudah sesuai dengan persyaratan pH kulit. pada uji viskositas, formulasi II dan III memnuhi persyaratan viskositas. Uji daya sebar, formulasi I sudah sesuai dengan persyaratan gel. Uji daya lekat, ketiga formulasi sudah sesuai dengan persyaratan daya lekat, uji waktu kering, ketiga formulasi sudah sesuai dengan persyaratan uji waktu kering. uji iritasi menunjukkan ketiga formulasi tidak menumbulkan reaksi, yang artinya ketiga formulasi aman untuk digunakan. Formulasi yang optimal yaitu formulasi I yang dilihat dari nilai tengah dari uji evaluasi yang dilakukan.
Evaluation and Test of Activity of Anti-Acne Peel-Off Mask Preparation Formulation of Brotowali Stem Extract (Tinospora crispa L.)
Authors: Amelia Norrahmi , Malahayati Siti , Melviani Melviani , Noval Noval
Published: August 2024

Background: Facial skin care for acne treatment is better formulated in topical form, this is due to the duration of the active substances that interact with the skin. One dosage form is a peel-off mask with active substances brotowali stems which contain flavanoids, tannins, alkaloids as antibacterial causes acne.
Objective: Analyzing the effect of variations in the concentration of brotowali stem extract (Tinospora crispa L.) on physicochemical evaluation and antibacterial activity of optimal anti-acne peel-off mask preparation formulations
Methods: The research method used is True Experimental with a posttest only control group design research design. Make peel-off mask formulations with variations in extract concentrations of 20%, 30%, and 40%. The evaluation then includes organoleptis, homogeneity, dispersion, adhesion, dry time, pH, viscosity, and antibacterial activity tests, statistically analyzed using One Way ANOVA
Results: Qualify in the organoleptis test is formula II (30%) and III (40%), the dispersion test is formula I (20%) and II (30%) with a p-value of 0.022, the adhesion test of all formulations with a p-value of 0.014, the dry time test of all formulations with a p-value of 0.000, the pH test is formula I (20%) with a p-value of 0.000, the viscosity test is formula II (30%) with a p-value of 0.000. The diameter of the formula's third inhibitory zone against propionibacterium acnes was 8.61mm ± 0.19 respectively; 14.31mm ± 3.88, and 15.54mm ± 4.80 with a p-value of 0.012
Conclusion: Variations on concentration of brotowali stem extract have an influence on physicochemical evaluation and antibacterial activity, the most optimal formulation is formulation II (30%)
Aktivitas Antioksidan dan Penetapan Kadar Flavonoid Daun Sirih Merah (Piper crocatum Ruiz & Pav) Dengan Variasi Ukuran Partikel Serbuk Simplisia
Authors: Oktavia Rissa , Rohama Rohama , Saputri Rina
Published: August 2024

Latar belakang: Sirih merah (Piper crocatum Ruiz & Pav) merupakan tanaman berkhasiat yang dimanfaatkan masyarakat Tehang, Kalimantan Tengah secara empiris untuk penyembuhan luka. Kemampuan daun sirih merah dalam menyembuhkan luka dikaitkan dengan sifat antiinflamasi dari metabolit sekunder golongan flavonoid yang terkandung di dalamnya yang sekaligus memiliki peran sebagai sumber antioksidan. Ukuran partikel akan mempengaruhi jumlah senyawa bioaktif dalam suatu ekstrak.
Tujuan: Mengetahui perbedaan aktivitas antioksidan dan kadar flavonoid ekstrak etanol daun sirih merah dengan adanya variasi ukuran partikel serbuk simplisia.
Metode: Penelitian kuantitatif true eksperimental yang membagi menjadi dua kelompok percobaan yaitu ekstrak daun sirih merah dengan ukuran partikel mesh 40/60 dan 60/80. Pengujian aktivitas antioksidan dengan metode DPPH dan penetapan kadar flavonoid dengan metode Spektrofotometri UV-Vis.
Hasil: Hasil pengujian aktivitas antioksidan berdasarkan nilai IC50 pada  ukuran partikel mesh 40/60 dan mesh 60/80 sebesar 5,96 ppm dan 2,74 ppm. Hasil penetapan kadar flavonoid pada masing-masing ukuran partikel mesh 40/60 dan 60/80 sebesar 1,448 mg QAE/g dan 3,5 mg QAE/g. Analisis statistik dengan uji Mann Whitney pada tiap kelompok menunjukkan adanya perbedaan yang signifikan (p value 0,025 < 0,05).
Kesimpulan: Simpulan penelitian ini Terdapat perbedaan yang signifikan dengan adanya variasi ukuran partikel terhadap aktivitas antioksidan dan kadar flavonoid. Aktivitas antioksidan dan kadar flavonoid terbesar diamati pada ekstrak dengan ukuran partikel mesh 60/80. Semakin kecil ukuran partikel maka semakin kuat antioksidan dan tingginya kadar flavonoid.
Kata Kunci: antioksidan, daun sirih merah, flavonoid, ukuran partikel
Molecular mechanism of autophagy in porcine reproductive and respiratory syndrome virus infection
Authors: Chen Xiaoyong , Yu Ziding , Li Wenfeng
Published: August 2024

Porcine reproductive and respiratory syndrome virus (PRRSV), a significant pathogen affecting the swine industry globally, has been shown to manipulate host cell processes, including autophagy, to facilitate its replication and survival within the host. Autophagy, an intracellular degradation process crucial for maintaining cellular homeostasis, can be hijacked by viruses for their own benefit. During PRRSV infection, autophagy plays a complex role, both as a defense mechanism of the host and as a tool exploited by the virus. This review explores the current understanding of the molecular mechanisms underlying autophagy induction under PRRSV infection, its impact on virus replication, and the potential implications for viral pathogenesis and antiviral strategies. By synthesizing the latest research findings, this article aims to enhance our understanding of the intricate relationship between autophagy and PRRSV, paving the way for novel therapeutic approaches against this swine pathogen.
Mice lacking ASIC2 and βENaC are protected from high-fat-diet-induced metabolic syndrome
Authors: Hamby Madison , Stec David E. , Hildebrandt Emily , Stec Donald F. , Drummond Heather A.
Published: August 2024

Introduction

Degenerin proteins, such as βENaC and ASIC2, have been implicated in cardiovascular function. However, their role in metabolic syndrome have not been studied. To begin to assess this interaction, we evaluated the impact of a high fat diet (HFD) on mice lacking normal levels of ASIC2 (ASIC2-/-) and βENaC (βENaCm/m).

Methods

Twenty-week-old male and female mice were placed on a 60% HFD for 12 weeks. Body weight was measured weekly, and body composition by non-invasive ECHO MRI and fasting blood glucose were measured at 0, 4, 8 and 12 weeks. A glucose tolerance test was administered after 12 weeks. Differences between ASIC2-/-/βENaCm/m and WT groups were compared using independent t-tests or ANOVA where appropriate within each sex. Data are presented as mean ± SEM and ASIC2-/-/βENaCm/m vs. WT.

Results

At 20 weeks of age, ASIC2-/-/βENaCm/m mice (n=9F/10M) weighed less and gained less weight than WT (n=12F/16M). Total body fat and lean body masses were reduced in female and male ASIC2-/-/βENaCm/m mice. Total body fat and lean body masses as % control were identical at the end of 12 weeks. Fasting blood glucoses were lower in female and male ASIC2-/-/βENaCm/m vs. WT mice after 12 weeks HFD. The area under the curve for the glucose tolerance test was reduced in female and tended (p=.079) to decrease in male ASIC2-/-/βENaCm/m. Plasma leptin and insulin were reduced in female and male ASIC2-/-/βENaCm/m vs. WT mice. Plasma insulin in female ASIC2-/-/βENaCm/m mice remained unchanged throughout the HFD period. Liver and liver fat masses, as well as percent liver fat, were reduced in both female and male ASIC2-/-/βENaCm/m mice after HFD. Plasma triglycerides, cholesterol, LDL- and HDL-cholesterols were markedly improved in male and/or female ASIC2-/-/βENaCm/m following the HFD.

Discussion

These novel findings suggest that loss of ASIC2 and βENaC offer a significant protection against HFD-induced metabolic syndrome.
Research progress of SREBP and its role in the pathogenesis of autoimmune rheumatic diseases
Authors: Xu Xiaofen , Jin Wumeng , Chang Runyu , Ding Xinghong
Published: August 2024

Autoimmune rheumatic diseases comprise a group of immune-related disorders characterized by non-organ-specific inflammation. These diseases include systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), ankylosing spondylitis (AS), gout, among others. Typically involving the hematologic system, these diseases may also affect multiple organs and systems. The pathogenesis of autoimmune rheumatic immune diseases is complex, with diverse etiologies, all associated with immune dysfunction. The current treatment options for this type of disease are relatively limited and come with certain side effects. Therefore, the urgent challenge remains to identify novel therapeutic targets for these diseases. Sterol regulatory element-binding proteins (SREBPs) are basic helix-loop-helix-leucine zipper transcription factors that regulate the expression of genes involved in lipid and cholesterol biosynthesis. The expression and transcriptional activity of SREBPs can be modulated by extracellular stimuli such as polyunsaturated fatty acids, amino acids, glucose, and energy pathways including AKT-mTORC and AMP-activated protein kinase (AMPK). Studies have shown that SREBPs play roles in regulating lipid metabolism, cytokine production, inflammation, and the proliferation of germinal center B (GCB) cells. These functions are significant in the pathogenesis of rheumatic and immune diseases (Graphical abstract). Therefore, this paper reviews the potential mechanisms of SREBPs in the development of SLE, RA, and gout, based on an exploration of their functions.
Mitochondrial chaperon TNF-receptor- associated protein 1 as a novel apoptotic regulator conferring susceptibility to Pneumocystis jirovecii pneumonia
Authors: Amali Aseervatham Anusha , Paramasivam Kathirvel , Huang Chiung Hui , Joshi Abhinav , Hirpara Jayshree L. , Ravikumar Sharada , Sam Qi Hui , Tan Rachel Ying Min , Tan Zhaohong , Kumar Dilip , Neckers Leonard M. , Pervaiz Shazib , Foo Roger , Chan Candice Y Y , Zhu Jin , Lee Cheryl , Chai Louis Yi Ann
Published: August 2024

Molecular chaperons stabilize protein folding and play a vital role in maintaining tissue homeostasis. To this intent, mitochondrial molecular chaperons may be involved in the regulation of oxidative phosphorylation and apoptosis during stress events such as infections. However, specific human infectious diseases relatable to defects in molecular chaperons have yet to be identified. To this end, we performed whole exome sequencing and functional immune assessment in a previously healthy Asian female, who experienced severe respiratory failure due to Pneumocystis jiroveci pneumonia and non-HIV-related CD4 lymphocytopenia. This revealed that a chaperon, the mitochondrial paralog of HSP90, TRAP1, may have been involved in the patient’s susceptibility to an opportunistic infection. Two rare heterozygous variants in TRAP1, E93Q, and A64T were detected. The patient’s peripheral blood mononuclear cells displayed diminished TRAP1 expression, but had increased active, cleaved caspase-3, caspase-7, and elevated IL-1β production. Transfection of A64T and E93Q variants in cell lines yielded decreased TRAP1 compared to transfected wildtype TRAP1 and re-capitulated the immunotypic phenotype of enhanced caspase-3 and caspase-7 activity. When infected with live P. jiroveci, the E93Q or A64T TRAP1 mutant expressing cells also exhibited reduced viability. Patient cells and cell lines transfected with the TRAP1 E93Q/A64T mutants had impaired respiration, glycolysis, and increased ROS production. Of note, co-expression of E93Q/A64T double mutants caused more functional aberration than either mutant singly. Taken together, our study uncovered a previously unrecognized role of TRAP1 in CD4+ lymphocytopenia, conferring susceptibility to opportunistic infections.