bluuebunny/crossref_metadata_2025 huggingface dataset:
Condições de saúde de docentes universitários vinculados a uma instituição federal de ensino superior no interior do nordeste do Brasil
Authors: Jardim Renata , Oliveira Junior Manoel Gomes de , Schott Marcia , Reis Alan Santos , Matos Luiz Eduardo Oliveira
Published: August 2022

O presente trabalho tem como objetivo investigar as condições de saúde docente em uma Instituição de Ensino Superior Federal no interior do nordeste brasileiro. Trata-se de um estudo transversal descritivo, realizado com 39 docentes da Universidade Federal de Sergipe. Dos 39 entrevistados, a maioria era do sexo feminino, casada, branca e com doutorado. Constatou-se que 74% (n=29) dos profissionais declararam insatisfeitos/muito insatisfeitos com as atividades desenvolvidas no trabalho e 31% (n=12) referiram alguma morbidade. Dentre as morbidades referidas, houve uma maior prevalência de doenças relacionadas à saúde mental (50%; n=6). Os dados obtidos mostram elevada prevalência de insatisfação com as atividades desenvolvidas na docência, bem como agravos na saúde mental, apesar da motivação e qualidade de vida no trabalho relativamente alta.
Banho de Sol para Pacientes Internados: Uma estratégia de humanização
Authors: Comym Viviane da Conceição Carius , Fabri Janaína Mengal Gomes , Pereira Eliane Ramos , Silva Rose Mary Costa Rosa Andrade , Pereira Adriana Matos , Garofalo Regina da Cruz , Barbosa Joice Cesar de Aguiar , Sousa Patrícia da Rocha , Porto Tainara Serodio Amim Rangel , Amaral Paula de Rezende Gallino  Alves do
Published: August 2022

O ambiente físico pode ser responsável pelo desenvolvimento de distúrbios psicológicos, pela desorientação e privação de sono. Somam-se a isso, as implicações decorrentes da internação hospitalar, dentre as quais se destacam o afastamento do doente do convívio do lar, das atividades cotidianas de lazer e laboral, e a introdução de novos hábitos, influenciando diretamente na saúde mental. A terapia de Banho de Sol, caracterizada pela exposição à luz solar, além de aliviar os efeitos emocionais decorrentes do processo de internação hospitalar, contribui para a manutenção dos níveis séricos de vitamina D, responsável pelo metabolismo da insulina, regulação do metabolismo de minerais e do sistema imunológico, cardiovascular e musculoesquelético, e nos níveis séricos melatonina e serotonina, favorecendo, assim, a melhora do estado de humor. Nesta perspetiva, o objetivo geral é refletir sobre os benefícios do banho de sol para pacientes internados. Trata-se de um estudo descritivo, qualitativo e reflexivo. Observou-se que as estratégias de Humanização em Saúde são essenciais para a reabilitação e recuperação dos pacientes internados. A literatura ratifica repercussões positivas na saúde física e psíquica através da prática regular do banho de sol. A exposição solar reduz os efeitos psíquicos da internação prolongada e previne inúmeras doenças. Conclui-se que a rotina do Banho de Sol é uma tecnologia leve de cuidado, humanizada, e importante para a adesão ao tratamento. Sendo relevante a disseminação do conhecimento acerca desta estratégia de humanização para a promoção do bem-estar.
Segurança do paciente: conexões de dispositivos
Authors: Amarijo Cristiane Lopes , Figueira Aline Belletti , Gonçalves Naiane Glaciele da Costa
Published: August 2022

Introdução: Anualmente, cerca de 100 mil pessoas morriam nos hospitais dos Estados Unidos vítimas de eventos adversos. Após essa divulgação surgiu a Era da Segurança do Paciente. Objetivo: Pretende-se ampliar a reflexão sobre os erros nas conexões de dispositivos terapêuticos que podem acarretar em eventos adversos graves, até mesmo letais. Metodologia: Reflexão teórica envolveu leitura, análise e interpretação de artigos que serviram de base às fases desta construção. Resultados: Após a leitura das publicações selecionadas elaborou-se oito categorias, intituladas: Dados estatísticos de eventos adversos; Errar é humano, evento adverso é falha no sistema; Protocolo de Segurança na Prescrição; Uso e Administração de Medicamentos; Cultura de segurança; Coparticipação do paciente; Educação Permanente e Formação acadêmica. Conclusão: A cultura de segurança do paciente deve ser amplamente disseminada nos serviços de saúde. Falhas e erros humanos são esperados em qualquer instituição e, por isso, é imprescindível implementar estratégias para a prevenção dos mesmos.
Paralisia do nervo oculomotor como manifestação inicial de esclerose múltipla: Relato de caso
Authors: Oliveira Caroline Solana de , Bastiani Felipe Gustavo de , Rodrigues Carlos Frederico Almeida
Published: August 2022

Objetivo: Descrever um caso clínica de esclerose múltipla com manifestação atípica em relação aos sinais e sintomas iniciais, faixa etário e gênero. Metodologia: Relato de caso com base no prontuário de um paciente que esteve internado no Hospital Policlínica Pato Branco, na cidade de Pato Branco, no Paraná, por paralisia unilateral do nervo oculomotor, diagnosticando-se esclerose múltipla posteriormente. Descrição do caso e discussão: O referido caso teve início com estrabismo convergente, diplopia e ptose palpebral, em olho direito, caracterizando paralisia do III nervo craniano à direita, sem outros sinais e sintomas associados. Foi feita investigação por ressonância magnética e pela análise de líquor. A esclerose múltipla é uma doença desmielinizante que prejudica a transmissão do impulso nervoso, resultando nas mais diversas manifestações clínicas, de acordo com a área do sistema nervoso central que é afetada  e acomete, principalmente, mulheres jovens e brancas, entre a terceira e a quarta décadas de vida, iniciando tipicamente com um quadro agudo ou subagudo de alterações visuais ou da sensibilidade Conclusão: Somando-se a clínica apresentada aos exames complementares foi possível inferir o diagnóstico de esclerose múltipla, mesmo sendo um paciente com características atípicas para a doença em relação ao gênero, à idade e à apresentação inicial.
Uso de Tecnologia Educativa no Ensino-aprendizagem dos graduandos de Enfermagem: Relato de experiência
Authors: Carvalho Rozana Neves Guimarães de , Pereira Juliana Dias Souto , Souza Claudio José de , Silvino Zenith Rosa
Published: August 2022

Objetivo: discorrer acerca das experiências do desenvolvimento e impressões sobre o uso de jogo no formato de vídeo para o ensino-aprendizagem dos acadêmicos de enfermagem de uma Universidade. Método: trata-se de um relato de experiência, desenvolvido no decorrer da disciplina de parasitologia em uma Universidade durante o segundo semestre de 2020.2, elaborado em três etapas: a criação do jogo, a avaliação prévia por voluntários acadêmicos de enfermagem e de biologia do instrumento com identificação de erros e a aplicação da ferramenta educativa via Google Meet®. Resultados e discussão: o jogo sofreu ajustes mediante as considerações dos colaboradores e acadêmicos de enfermagem. Considerações finais: depreende-se que o jogo oferecido em formato de vídeo implica em um maior engajamento dos acadêmicos na aula, tornando o processo ensino-aprendizagem mais efetivo em função da fixação de um saber previamente visto e oportunidade de retirada de dúvidas sobre as questões abordadas.Além disso, oportuniza uma maior interação entre o acadêmico e docente, avaliação do desempenho dos estudantes em um ambiente descontraído e autoavaliação do acadêmico.
PENYULUHAN DAN FOLLOW-UP BAHAYA VARIAN OMICRON UNTUK MENCEGAH PENYEBARAN COVID-19 DAERAH MALANG DI SMK PGRI SINGOSARI
Authors: Muhaidin Faisal , Cahyono Nur , Anantyarta Primadya
Published: August 2022

Covid-19 is a virus that causes a pandemic throughout the world, including in Indonesia. This virus develops rapidly and mutates into various variants, one of which is the Omicron variant. This virus causes various kinds of effects. The way to break the chain of spread of the Covid-19 virus is to implement health protocols. This community service has the aim of providing counseling and follow-up on the dangers of COVID-19, the Omicron variant, to prevent the spread of COVID-19 cases at SMK PGRI Singosari. This outreach activity is carried out in 3 stages, namely pre-PMBP activities, implementation of PMBP Activities, and Post-PMBP Activities (Follow-Up). In conclusion, breaking the chain of spread of COVID-19 can be done by implementing health protocols according to government recommendations and must be accompanied by a healthy lifestyle such as consuming a balanced nutritious diet, exercise, and adequate rest and vaccination.
PENCEGAHAN BULLYING KALANGAN REMAJA DI DESA NGIJO KECAMATAN KARANGPLOSO
Authors: Setiani Puspita Pebri , Wardana M. Iksan Gafa , Anisa Nur
Published: August 2022

Bullying is an act of using power to hurt a person or group of people verbally, physically, or psychologically so that the victim feels depressed, traumatized, and helpless. Teenagers who are victims of bullying are more at risk of health problems both physically and mentally. Bullying behavior often occurs if someone has a deficiency in him, both physically and mentally. Increasing the understanding of teenagers regarding bullying behavior can reduce cases of bullying, why prevention of bullying is very important from a young age because basically this bullying behavior is very dangerous. The impact of bullying for adolescents is in the form of mental disorders ranging from sensitivity, extreme anger, depression, low self-esteem, anxiety, decreased sleep quality, and feeling afraid to get along in a social environment. Through the bullying prevention counseling method, it is expected to have awareness and expertise in understanding the dangers of bullying behavior. The results of this activity are expected to be able to understand the dangers of bullying in an effort to prevent bullying behavior among teenagers.
IMPLEMENTASI BIMBINGAN BELAJAR DAN PENANAMAN NILAI-NILAI KEARIFAN LOKAL PADA TRADISI BATIK GUNA MEWUJUDKAN CIVIS DISPOSITION GENERASI MUDA DI DESA GUNUNGSARI KECAMATAN BUMIAJI KOTA BATU
Authors: Susandi Susandi , Maulida Azizah Emil Kholif , Afiq Grace Debora Marcheline , Saputri Naudy Dian Ayu , Laksono Muhammad Rizal
Published: August 2022

Potential-based community service (PMBP) is one of the important activities for the academic community as academic functional staff to develop knowledge, skills, and solve problems. This community service aims to provide education to the community about the importance of education, skills, and environmental stewardship. Individual potential-based community service activities (PMBP) of IKIP Budi Utomo Malang were carried out in Gunungsari Village, Pegergunung Hamlet and Claket Hamlet, Bumiaji Distriet, Batu City. This service activity is carried out from February 1 to March 31, 2022. This activity certainly has an impact on change for the village, where the results can be obtained, namely increasing learning development and being able to make products with their own hands that can be used as tablecloths. The result of this community service is an increase in knowledge, understanding, and awareness of education and the environment. However, this program cannot be carried out continuously due to time constraints in the implementation of PMBP. Therefore, we feel that this program is very good and needs to be followed up by the IKIP BUDI UTOMO MALANG campus
OPTIMALISASI KEGIATAN PENGABDIAN MASYARAKAT DI CILIWUNG GANG 1 RT 07 RW 11 MALANG
Authors: Napfiah Siti , Yazidah Nok Izatul , Thalib Indah Hartati A.
Published: August 2022

Potential-Based Community Service (PMBP) is an extracurricular activity that aims to provide services to the community). This is carried out as a form of elaboration in the implementation of the Tri Dharma of Higher Education in which every intellectual candidate not only understands and understands enough about science and technology (IPTEK), but there needs to be a correlation in the level of social life with society in general and more specifically. for people who need the role of students. In the implementation of this Potential-Based Community Service (PMBP) activity, the executor devotes himself to four types of activities, which are carried out in Ciliwung Gang 1 RT 07 RW 11, Purwantoro Village, Blimbing District, Malang City, East Java. The four types of activities are conducting tutoring for early childhood, participating in community organizations in Ciliwung Gang 1 affected by the Covid-19 pandemic, such as providing counseling by spraying disinfectants, social service work, and participating in PKK activities.
SOSIALISASI DAN PENDAMPINGAN PEMBELAJARAN PAUD BERBASIS HYBRID BAGI GURU LEMBAGA PENDIDIKAN ANAK HEBAT INDONESIA (AHE) DI KEC. TUMPANG, KAB. MALANG
Authors: Suhartatik Suhartatik , Purwati Titik , Bangun Wilyati Agustina
Published: August 2022

The evolution of education  for early childhood (PAUD)  is very crucial  in digital period, in order to adapt currently situation and conditions. The teachers have to be able to create  and develop  various media that fitted with the child’s  age and characteristics. The objective of hybrid- based learning assistance  for early childhood education (PAUD)  aims to offer  the comprehension   for the teacher how to absorb  and develop  teaching method and media for early childhood  by using various resources. This activity covers some agendas i.e initial activities, implementation and evaluation.  The target of the activities are expected that  the teachers are able to catch on  hybrid-based learning, moreover  the teacher are able to develop internet-based media for teaching PAUD, and they can utilize  innovative teaching aids. The last, the activity  will contribute  the output of  scientific publication.
PENGEMBANGAN POTENSI DIRI MELALUI KEGIATAN PENGABDIAN KEPADA MASYARAKAT
Authors: Laru Ludfina , Sulistyorini Yunis
Published: August 2022

Potential-Based Community Service (PMBP) is an extracurricular activity that aims to provide services to the community). This is carried out as a form of elaboration in the implementation of the Tri Dharma of Higher Education in which every intellectual candidate not only understands and understands enough about science and technology (IPTEK), but there needs to be a correlation in the level of social life with society in general and more specifically. for people who need the role of students. In the implementation of this Potential-Based Community Service (PMBP) activity, the executor devotes himself to four types of activities, which are carried out in Ciliwung Gang 1 RT 07 RW 11, Purwantoro Village, Blimbing District, Malang City, East Java. The four types of activities are conducting tutoring for early childhood, participating in community organizations in Ciliwung Gang 1 affected by the Covid-19 pandemic, such as providing counseling by spraying disinfectants, social service work, and participating in PKK activities
PELATIHAN DAN PENDAMPINGAN PEMBUATAN YOGHURT PADA SANTRI TPQ BAITUL KHOIR
Authors: Agustin Khusnia , Hidayati Nuril , Prayitno Trio Ageng
Published: August 2022

The purpose of this service activity is to training and mentoring TPQ Baitul Khoir students in making yogurt as a provision for future businesses. The method of service implementation includes Observation, Planning, Implementation, Evaluation, and Reflection (OPIER). Observations were made through field reviews and direct interviews with the guardians of TPQ Baitul Khoir students. Planning is made based on the results of observations. The implementation of the service is carried out based on the plans that have been made. Evaluation is carried out to determine the impact of the implementation of the service. Reflection to analyze obstacles and follow-up plans for the next service activity. The results of the service show that the students of TPQ Baitul Khoir can make yogurt. Santri TPQ Baitur Khoir is very enthusiastic and passionate about making yogurt. The obstacle experienced was that the service area was relatively narrow, thereby reducing the space for the service team and participants. Thus, this service concludes that service activities can train and assist TPQ Baitul Khoir students in making yogurt as a business provision in the future when they want to earn income from a business.
The Effect of Sulforaphane on Perinatal Hypoxic-Ischemic Brain Injury in Rats
Authors: KAPOOR S , KALA D , SVOBODA J , DANĚK J , FARIDOVÁ A , BRNOLIAKOVÁ Z , MIKULECKÁ A , FOLBERGROVÁ J , OTÁHAL J
Published: August 2022

Perinatal hypoxic-ischemic insult (HII) is one of the main devastating causes of morbidity and mortality in newborns. HII induces brain injury which evolves to neurological sequelae later in life. Hypothermia is the only therapeutic approach available capable of diminishing brain impairment after HII. Finding a novel therapeutic method to reduce the severity of brain injury and its consequences is critical in neonatology. The present paper aimed to evaluate the effect of sulforaphane (SFN) pre-treatment on glucose metabolism, neurodegeneration, and functional outcome at the acute, sub-acute, and sub-chronic time intervals in the experimental model of perinatal hypoxic-ischemic insult in rats. To estimate the effect of SFN on brain glucose uptake we have performed 18F-deoxyglucose (FDG) μCT/PET. The activity of FDG was determined in the hippocampus and sensorimotor cortex. Neurodegeneration was assessed by histological analysis of Nissl-stained brain sections. To investigate functional outcomes a battery of behavioral tests was employed. We have shown that although SFN possesses a protective effect on glucose uptake in the ischemic hippocampus 24 h and 1 week after HII, no effect has been observed in the motor cortex. We have further shown that the ischemic hippocampal formation tends to be thinner in HIE and SFN treatment tends to reverse this pattern. We have observed subtle chronic movement deficit after HII detected by ladder rung walking test with no protective effect of SFN. SFN should be thus considered as a potent neuroprotective drug with the capability to interfere with pathophysiological processes triggered by perinatal hypoxic-ischemic insult.
RADIOGRAPHER CHARACTERISTICS RELATIONSHIP WITH APPLICATION PATIENT SAFETY RADIATION IN SLEMAN DISTRICT
Authors: Utami Asih Puji , Anggraeni Ari , Faesol Ahmad
Published: August 2022

Radiology installation one part of service in the hospital must consider and pay attention to patient safety. Radiographers are executor of services in radiology. Research on the relationship between radiographic characteristics and the application of patient safety radiation aims to analyze the effect of characteristic factors, age, sex, years of service, and PPR training. Based on research conducted by the author, the mass of work has a great influence on experience in an action taken. The mass of work of more than 5 years has an effect on improving the quality of patient safety application because it learns from a mistake to avoid the same mistake. Of the 4 gender characteristics, it did not show any relationship with the application of patient safety radiation with = 0.05, a p value of 0.072 was obtained. Characteristics of age more than 30 years to apply patient safety radiation is better than the age of 20-30 years. Characteristics of a working period of more than 5 years will make the implementation of patient safety radiation better. While the last characteristic is that PPR training has a relationship with the practice of implementing patient safety radiation. This research is expected to be able to contribute to science, especially in the field of implementing patient safety at the Radiology Installation so that radiographers can provide the best service by prioritizing patient safety.
Kelayakan Usaha Penangkapan Ikan Pada Alat Tangkap Pole and Line di Perairan Kabupaten Kolaka
Authors: Saleh Ramlah , Adimu Hasan Eldin , Fekri Latifa
Published: August 2022

Kegiatan Penangkapan ikan menggunkan Pole and line sangat banyak ditemukan diperiaran Indonesia bagian timur. Nelayan pengguna pole and line target utamanya adalah ikan cakalang tak terkecuali di perairan Kabupaen Kolaka. Penelitian ini bertujuan untuk mengetahaui kelayakan usaha pada kegiatan penangkapan ikan berdasarkan alat tangkap Pole and line di perairan Kabupaten Kolaka. Pelaksanaan penelitian pada bulan April-Juni 2018. Informasi data diperoleh melalui 14 usaha penangkapan ikan nelyan pole and line di perairan Kolaka yang ditentukan secara purposif sampling. Data diperoleh berdasarkan hasil wawancara lapangan dengan responden, selain itu diperoleh dari instansi dinas perikanan Kabupaten Kolaka. Analisis statistik deskiriptif digunakan untuk mengetahui pendapatan hasil usaha. Analisis data memperlihatkan nilai rata-rata pendapatan unit pole and line sebesar Rp. 25.245.200/bulan, dengan tingkat efesiensi yang ditunjukkan oleh R/C = 1,24. Hasil ini menandakan bahwa kegiatan penangkapan ikan pole and line di Kabupaten Kolaka layak dilanjutkan.
Solar System Wave Function
Authors: Soltani Abolfazl
Published: August 2022

Pluto, Ceres and all planets of solar system except Neptune, with a high approximation, follow a law called Titius-Bode law (TBL) or Bode law, which can by no means be considered as a stochastic event. This law shows that the distance of the planets from the sun in Solar system is regulated. Here, we prove that, probably, the existence of a standing and cosine wave packet in solar system, with the wavelength λ = 0.6 AU (AU represents the distance of earth from the sun) and the phase constant ∅0=π/6, is the reason for TBL. In this article we will obtain the equation of this wave packet empirically. Finally, we will prove that without solar system wave function, it is not possible to reach to the TBL from the protoplanetary disk of solar system. Here we prove that the nebular theory without our wave theory is an incomplete theory.
Pineapple Theorem ( A prime number formular and proof of Goldbach Conjecture)
Authors: Kawinga Gibbs
Published: August 2022

The pineapple theorem is a prime number formulae that generates prime numbers, prime factors,test for primality and prove the Goldbach Conjecture.
Perubahan Makna pada Terjemahan Lirik lagu "In Control" Setelah Dialihbahasakan
Authors: Johanis Yeremia Guinea , Pendit Ni Putu Meri Dewi
Published: August 2022

This study aims to describe the process of translating spiritual songs from English to Indonesian and vice versa. The approach used is an interdisciplinary approach due to not only a linguistic approach, but also music and theology. The problem is the difference in the number of syllables needed to convey the message in a complete sentence with the availability of syllables in the melody. The translation method of Newmark was applied, which focuses on the Target Language. It uses two songs that have been translated by the author and have been sung by the congregation during a worship in the church. The results of the translation through testimonies given by native English and Indonesian speakers, where both parties actively understand both languages, with a background in music knowledge and faith. The results of the study concluded that there would be no translated song that could be one hundred percent accurate in transferring the message of the lyrics and intangible elements in a song, but it could be attempted as close as possible by looking at the parallels of words and meanings, the parallels of song structure, and the parallels of the impact of the song on listeners of target language.

 

Penelitian ini bertujuan untuk menggambarkan proses penerjemahan lagu rohani dari bahasa Inggris ke bahasa Indonesia dan sebaliknya. Pendekatan yang digunakan adalah pendekatan interdisipliner dikarenakan bukan hanya pendekatan kebahasaan, namun juga musik dan juga teologi. Masalah yang dihadapi adalah perbedaan jumlah suku kata yang dibutuhkan untuk membawakan pesan dalam kalimat secara utuh dengan ketersediaan suku kata dalam melodi. Metode yang digunakan mengacu pada metode penerjemahan menurut Newmark, yang menekankan pada bahasa sasaran. Digunakan dua buah lagu yang telah diterjemahkan sendiri oleh penulis dan telah dinyanyikan oleh jemaat dalam proses peribadatan dalam gereja. Penutur asli bahasa Inggris dan Indonesia yang berlatar belakang musik, ilmu dan keimanan juga memberikan komentar positif terhadap terjemahan lagu-lagu tersebut. Hasil penelitian menunjukkan bahwa lagu-lagu rohani tersebut tidak dapat diterjemahkan secara sempurna ke dalam bahasa sasaran, terutama yang berkaitan dengan pesan-pesan lirik dan unsur-unsur tidak berwujud dari lagu tersebut, namun penerjemah dapat menerjemahkannya sedekat mungkin ke dalam bahasa sasaran dengan melihat kesepadanan kata dan makna, struktur lagu, dan dampak lagu bagi pedengar di bahasa sasaran.
Studi Kasus Penerjemahan Teks Eksplanasi Menggunakan Metode Penerjemahan Semantis-Komunikatif pada "Routledge Handbook on Sufism"
Authors: Awalukita Melinda , Afriliani Afriliani
Published: August 2022

Explanatory text is a text that explains the process related to natural, social, and cultural phenomena on a certain theme which is equipped with an explanation (Karnedi, 2014). This scientific work is presented as a case study of translating an explanatory text with a religious theme from the source language to the target language using the communicative-semantic translation method supported by a number of annotations related to the translation procedure. The annotation focuses on various spiritual, social, and cultural aspects of the book entitled Routledge Handbook on Sufism in the section on Sufism in Modern Morocco by Marta Dominguez Diaz. The purpose and benefit of writing this scientific paper is to provide an explanation of the translation of the beginning of a sociocultural phenomenon in the world of Islamic mystics that can develop in the country of Morocco at the end of the eighteenth century until today. The purpose of writing is to make it easier for readers to understand terms in spiritualist texts, as well as additional insight into the process of translating an explanatory text with a religious theme.
 
Teks eksplanasi adalah teks yang menerangkan proses berkaitan dengan fenomena alam, sosial, dan budaya atas tema tertentu yang dilengkapi dengan sebuah penjelasan (Karnedi, 2014). Karya ilmiah ini disajikan sebagai sebuah studi kasus penerjemahan teks eksplanasi bertema religi dari bahasa sumber ke bahasa sasaran dengan menggunakan metode penerjemahan komunikatif-semantis yang didukung dengan sejumlah anotasi terkait prosedur penerjemahannya. Anotasi menitikberatkan berbagai aspek spiritual, sosial, dan kultural dari buku yang berjudul Routledge Handbook on Sufism pada bagian Sufism in Modern Morocco karya Marta Dominguez Diaz. Tujuan dan manfaat dari penulisan karya ilmiah ini adalah untuk memberikan penjelasan penerjemahan tentang awal mula sebuah fenomena sosiokultural dalam dunia mistikus Islam dapat berkembang di negara Maroko di akhir abad kedelapanbelas hingga hari ini. Tujuan penulisan untuk memudahkan para pembaca dalam memahami istilah-istilah dalam teks spititualisme, serta sebagai wawasan tambahan mengenai proses penerjemahan suatu teks ekpslanasi bertema religi.
Idéburen välfärd i Sverige
Authors: Henrekson Ebba , Neubeck Truls
Published: August 2022

Syftet med artikeln är att göra en genomgång av den forskning som finns inom området idéburen välfärd i Sverige samt att identifiera behov av vidare forskning. Utifrån ett ökat intresse för civilsamhället generellt och idéburen välfärd specifikt söker vi svar på några frågor. Vilka vetenskapliga perspektiv har anlagts i studier om idéburna organisationers roll för välfärdens praktik? När är studierna gjorda? Vilka välfärdsområden har studerats? Och, handlar studierna om brukare, professionella, välfärdsproducerande organisationer eller samhället i stort? I artikeln analyseras 161 publicerade studier. Dessa har identifierats genom sökningar i tre akademiska databaser. Resultaten, som sammanfattas genom grafer och i form av en narrativ syntes, visar att forskningen om idéburen välfärd har ökat stadigt sedan tidigt 1990-tal. Den samlade forskningen på idéburen välfärd ger en förståelse av de politiska förändringsprocesser som påverkat den idéburna välfärdsproduktionen och hur dessa processer relaterar internationella trender. Slutligen argumenteras det för att det saknas forskning om faktiskt utförd produktion av välfärdstjänster i den idéburna sektorn och dess betydelse för den enskilda brukaren. Det gäller särskilt forskning om idéburen vård och skola.
Decellularized blood vessel development: Current state-of-the-art and future directions
Authors: Wang Xinyu , Chan Vincent , Corridon Peter R.
Published: August 2022

Vascular diseases contribute to intensive and irreversible damage, and current treatments include medications, rehabilitation, and surgical interventions. Often, these diseases require some form of vascular replacement therapy (VRT) to help patients overcome life-threatening conditions and traumatic injuries annually. Current VRTs rely on harvesting blood vessels from various regions of the body like the arms, legs, chest, and abdomen. However, these procedures also produce further complications like donor site morbidity. Such common comorbidities may lead to substantial pain, infections, decreased function, and additional reconstructive or cosmetic surgeries. Vascular tissue engineering technology promises to reduce or eliminate these issues, and the existing state-of-the-art approach is based on synthetic or natural polymer tubes aiming to mimic various types of blood vessel. Burgeoning decellularization techniques are considered as the most viable tissue engineering strategy to fill these gaps. This review discusses various approaches and the mechanisms behind decellularization techniques and outlines a simplified model for a replacement vascular unit. The current state-of-the-art method used to create decellularized vessel segments is identified. Also, perspectives on future directions to engineer small- (inner diameter >1 mm and <6 mm) to large-caliber (inner diameter >6 mm) vessel substitutes are presented.
Injectable light-assisted thermo-responsive methylcellulose-sodium humate hydrogel proposed for photothermal ablation and localized delivery of cisplatin
Authors: Ghorbani Farnaz , Ghalandari Behafarid , Liu Zichen , Li Dejian , Yu Baoqing
Published: August 2022

This study aimed to develop injectable light-assisted thermo-responsive methylcellulose hydrogels filled with sodium humate, which were proposed for photothermal ablation and localized cisplatin delivery. Sodium humate converts light energy from laser beams into thermal energy, which causes methylcellulose to gel, thereby controlling the release of chemotherapy agents. Meanwhile, light emission causes to the photothermal ablation of tumor cells. For determining the optimal production conditions, different concentrations of sodium humate and light emission times were investigated. Results show that hydrogel uniformity is highly dependent on variables. An increase in sodium humate concentration and emission time resulted in a slight reduction in swelling ratio and an increase in durability. According to the simulation conditions, the cisplatin release profile was consistent with a non-Fickian mechanism with a predominant erosion contribution. In conjugation with increasing light emission time and sodium humate content, the storage modulus and viscosity increased, demonstrating hydrogel’s sol-gel transition and long-lasting durability. The intrinsic fluorescence spectroscopy study revealed that the hydrogel-model protein complex empowered hydrogel bio-performance. Laser emission and cisplatin release synergistically reduced the number of viable osteosarcoma cell lines, suggesting the possibility of tumor ablation. This study describes the potential of simultaneous photothermal therapy and chemotherapy in osteosarcoma treatment, laying the groundwork for future preclinical and clinical trials.
Hybrid random utility-random regret model in the presence of preference heterogeneity, modeling drivers’ actions
Authors: Rezapour Mahdi , Ksaibati Khaled
Published: August 2022

Despite the importance of drivers’ actions and behaviors, the underlying factors to those actions have not received adequate attention. Understanding the factors contributing to various drivers’ actions before crashes could help policy makers to take appropriate actions to tackle those behaviors before crashes occur. One of the first steps could be to identify contributing factors to drivers’ actions by using a reliable statistical technique. It is reasonable to assume that drivers vary in their decision-making processes. Thus, in this study, in addition to the random utility maximization (RUM), the random regret minimization (RRM), as a psychological representation of the choice-making process, was considered. While most of the past studies, in the context of traffic safety, focused on either the RRM or RUM, both models’ frameworks as hybrid models might be needed to account for the heterogeneity of drivers’ decision-making behaviors. In addition, we accounted for the additional dimensions of preference heterogeneity in the latent class (LC) that the model might not capture. The results showed a significant improvement in the model fit of the mixed hybrid LC model compared with the standard hybrid and simple mixed RRM and RUM models. The emotional conditions of drivers, distraction, environmental conditions, and gender are some of the factors found to impact drivers’ choices. The results suggest that while the majority of attributes are processed according to the RUM, a significant portion of attributes are processed by the RRM. The hybrid model provides a richer understanding regarding factors to drivers’ actions before crashes based on different paradigms.
Endophthalmitis at a tertiary referral center: Characteristics and treatment outcomes over three decades
Authors: Zhang Wen-Fei , Zhao Xin-Yu , Meng Li-Hui , Chen Huan , Chen You-Xin
Published: August 2022

Purpose: To explore the incidence, pathogens, treatment, and prognosis of endophthalmitis.

Methods: Patients who were diagnosed with endophthalmitis from January 1990 to October 2020 at Peking Union Medical College Hospital were retrospectively reviewed and examined. Subgroup analysis was conducted regarding different initial treatment methods for eyes without concurrent retinal detachment (RD) at presentation.

Results: A total of 249 eyes of 233 patients were included in this retrospective study. The most common clinical scenario was exogenous endophthalmitis (60.6%). The most frequent bacteria and fungi were coagulase-negative staphylococci (10.0%) and candida (6.8%), respectively. Retinal with/without choroid detachment was the most common complication after treatment. Patients with endogenous endophthalmitis were more likely to have binocular involvement; there were also more patients with diabetes mellitus or immunosuppressive diseases, and the prognosis of visual acuity (VA) was poorer. There were more eyes with concurrent RD at presentation that underwent serious complications after treatment (p < 0.05), and the visual outcome was worse than that without concurrent RD (p < 0.05). Subgroup analysis was conducted according to different initial treatments in eyes without concurrent RD. Group 1 received pars plana vitrectomy (PPV) with intravitreal injection of antibiotics (IVI) as initial treatment, Group 2 was initially treated with IVI only, and Group 3 was initially treated with nonsurgical treatment. More eyes that initially received IVI alone and nonsurgical treatment required additional treatments, especially additional PPV. VA in both Groups 1 and 2 significantly improved by the final VA. However, there was no significant difference in final VA between the two groups. There was an insignificant trend that serious posttreatment complications were more common in Group 1. In Group 1, 17 eyes received silicone oil or gas tamponade at the same time, whereas 62 did not. Eyes that were initially treated with PPV + IVI while without tamponade needed more additional treatments and additional IVI.

Conclusion: Endophthalmitis is a devastating intraocular disease and requires early intervention. Endogenous endophthalmitis has a poorer visual prognosis than exogenous entity. PPV + IVI as an initial treatment may reduce additional therapy.
Case report: Transcatheter closure of a giant and tortuous right coronary artery to right ventricle fistula in an infant
Authors: Wu Yen-Hsien , Liu Yi-Ching , Chao Min-Fang , Dai Zen-Kong , Chen I-Chen , Lo Shih-Hsing , Hsu Jong-Hau
Published: August 2022

Congenital coronary artery fistulas (CAFs) are an uncommon congenital anomaly. While most patients are asymptomatic, life-threatening events including sudden death, myocardial ischemia, heart failure, infective endocarditis, and rupture of aneurysm may occur. Surgical ligation was once the standard choice of management of CAFs in the past. However, transcatheter closure of CAFs has become an emerging alternative to surgery in patients with suitable anatomy. We reported a 7-month-old infant with a giant and tortuous CAF that originated from the distal right coronary artery and drained into the right ventricle, and was successfully treated by transcatheter closure with an Amplatzer ductus occluder.
Association between statin use and the prognosis of patients with acute myocardial infarction complicated with diabetes
Authors: Lu Xuehao , Zhang Luming , Li Shaojin , He Dan , Huang Tao , Lin Hongsheng , Yin Haiyan , Lyu Jun
Published: August 2022

Background

Type 2 diabetes leads to an increase in the prevalence of lipid abnormalities, which increases the risk of cardiovascular disease. Therefore, current guidelines generally recommend the use of moderate or high-intensity statins in patients with type 2 diabetes. There are still few studies on the overall risk benefit balance of statins for acute myocardial infarction (AMI) patients with diabetes. Compared with other types of lipid-lowering drugs, the advantage of statins for the prognosis of patients with AMI has not yet been determined. We investigated the effects of statins and non-statins on intensive care unit (ICU) and inpatient mortality in patients with AMI and diabetes.

Methods

This study retrospectively collected all patients with AMI and diabetes in the Medical Information Mart Intensive Care-IV database. We assessed ICU and in-hospital mortality rates during hospitalization in both groups. The clinical end point was in-hospital mortality and ICU mortality. Kaplan-Meier and Cox proportional-hazards regression models were applied to analyze the correlation between the two groups and the outcomes.

Results

Data on 1,315 patients with AMI and diabetes were collected, among which 1,211 used statins during hospitalization. The overall in-hospital mortality of patients with AMI and diabetes was 17.2%, and the total ICU mortality was 12.6%. The in-hospital mortality was lower for the statin group than for the non-statin group (13.9% and 55.8%, respectively). Kaplan-Meier survival curves demonstrated that survival probability was higher in the statin group than in the non-statin group. In the cohort without hyperlipidemia, the statin group had lower risks of ICU death (HR = 0.12, 95% CI = 0.04–0.40) and in-hospital death (HR = 0.36, 95% CI = 0.16–0.84) compared with the non-statin group.

Conclusions

Statins can significantly reduce ICU and in-hospital mortality rates in patients with AMI and diabetes. Even in the population without hyperlipidemia, statins can still reduce the mortality in patients with AMI and diabetes.
Evaluating the variability of glacial lakes in the Kyrgyz and Teskey ranges, Tien Shan
Authors: Daiyrov Mirlan , Kattel Dambaru Ballab , Narama Chiyuki , Wang Weicai
Published: August 2022

The northern Tien Shan Mountains are one of the most hazardous areas in Kyrgyzstan due to frequent glacial lake outburst floods (GLOFs). The current status of glacial lakes in this region has not been reported in recent years. Therefore, this study investigates the variations of glacial lakes in the Kyrgyz and Teskey ranges using Sentinel-2 and PlanetScope optical satellite images from 2017 to 2019. Results confirm that there are 800 glacial lakes, of which 351 were in the Kyrgyz and 449 were in the Teskey Range. We found seasonality in the character of glacial lakes, most of which have been found to be unstable during our observation period. 242 glacial lakes showed significant variations in area. We found 46 newly emerging glacial lakes, five of which have rapidly expanded in the year since they formed, while 18 were found to have vanished. Thirteen lakes were found to be short-lived or unstable. In this study, 14 lakes showed a significant expansion of area. Such large variations in the glacial lakes are closely linked to local geomorphological conditions, local climate and glacier melt. We also identified a significant shift in the number of glacial lakes at altitudes over 3,500 m asl. It is associated with the mountain permafrost zone and variations of the glacier terminus. The current study recommends detailed investigation of glacial lakes in each season with the use of remote sensing and field surveys.
Near-surface characterization using urban traffic noise recorded by fiber-optic distributed acoustic sensing
Authors: Shao Jie , Wang Yibo , Zheng Yikang , Yao Yi , Wu Shaojiang , Yang Zesheng , Xue Qingfeng
Published: August 2022

The recently developed fiber-optic distributed acoustic sensing (DAS) technology has attracted widespread attention in engineering applications, oil exploration, and seismological research. Compared with the conventional geophones, DAS can acquire high-resolution data due to a dense sampling and can be deployed conveniently in the complex acquisition environment. These advantages of DAS make it promising for near-surface characterization in the urban city. In this study, a DAS line was utilized to record traffic noise seismic data in the urban city and to investigate the near-surface characterization. Seismic surface waves were reconstructed from the acquired traffic noises using seismic interferometry. Thereafter, we obtain the near-surface shear wave velocity profile below the DAS line by surface wave dispersion curve inversion using a Bayesian Markov Chain Monte Carlo method. The results demonstrate the effectiveness of DAS-based urban traffic noise in near-surface characterization.
Forest tourism development conflict analysis under carbon peak and neutrality goals—Based on graph model for conflict resolution
Authors: Zhao Rongrong , Chen Qiuhua , Kong Deyi , Song Yijing
Published: August 2022

To achieve carbon peaking and carbon neutrality goals, maintaining forest savings has become the key. How to reduce the damage of forest tourism development to the environment, reconcile conflicts, and promote the orderly implementation of forest tourism projects while maintaining forest savings is an important prerequisite for the development and construction of forest tourism. First, we constructed a fundamental Graph Model for Conflict Resolution (GMCR) during forest tourism development under carbon peak and neutrality goals. From the perspective of the dynamic interaction of conflict analysis, this article explains the game behavior behind the conflict of forest tourism development. Next, we calculated the equilibrium solution of a three-party game which means tourism enterprises adopt compensatory strategies, local residents support forest tourism development, and the government supports tourism enterprises for development projects, develops an ecological compensation system, and strengthens supervision. It provides a set of systematic and effective conflict analysis tools for stakeholders of forest tourism development projects and provides decision-making and reference information for the formulation of similar environmental resource development policies.
Change in phosphorus requirement with increasing grain yield for rice under saline-sodic stress in Northeast China
Authors: Wei Zhanxi , Zhang Yi , Liu Zhanfeng , Peng Mengsu , Wang Teng , Cao Ning
Published: August 2022

It is possible to simultaneously reduce both food security and environmental impact by understanding the relation between rice (Oryza sativa L.) grain yield and phosphorus (P) uptake requirements. The goal of this study was to determine P uptake requirements and relationship of P accumulation with yield formation at different rice grain yield levels under saline-sodic stress. A database comprising measurements in 28 plots in four on-farm research station located in saline-sodic soil area during the period 2018–2019 in Jilin province of Northeast China was used for the analyses. The grain yields of rice averaged 9.0 Mg ha−1 and varied from 5.11 to 13.41 Mg ha−1. The P uptake at late growth stages (heading and maturity) of rice gradually increased with increasing grain yield levels. The P requirement for producing 1 Mg grain (Preq.) were 4.61, 4.60, and 4.21 kg Mg−1 for grain yields ranging from <7.0, 8.0–9.5, and >10.0 Mg ha−1, respectively. The decrease in Preq. values with increasing grain yield was mainly attributable to the increase in the harvest index from 0.25 to 0.33. A larger proportion of the P was accumulated from heading to maturity stage when grain yields were higher than 8.0 Mg ha−1. The P uptake in leaves, stems and panicles at the maturity stage gradually increased with increasing grain yield levels. The results give a contribution to rice production in saline-sodic soils, and greatly optimize P management especially in high-yielding rice systems, furtherly improving food security in the Jilin province of China.
HHLA2 predicts improved prognosis of anti-PD-1/PD-L1 immunotherapy in patients with melanoma
Authors: Huang Fu-xue , Wu Jun-wan , Cheng Xia-qin , Wang Jiu-hong , Wen Xi-zhi , Li Jing-jing , Zhang Qiong , Jiang Hang , Ding Qiu-yue , Zhu Xiao-feng , Zhang Xiao-shi , Ding Ya , Li Dan-dan
Published: August 2022

Background

As a recognized highly immunogenic tumor, immune checkpoint blockades (ICB) have been widely used as a systemic treatment option for melanoma. However, only about half of treated patients could benefit from it in Caucasians, and only about 15% in Chinese melanoma patients. Robust predictive biomarkers are needed. HHLA2, a new-found member of B7 family, is generally expressed in kinds of tumors, such as melanoma. This study focuses on illustrating the prognostic value of HHLA2 in melanoma immunotherapy and its association with tumor-infiltrating lymphocytes.

Methods

HHLA2 expression in pan-cancer and the association with prognosis and immune microenvironment were identified by analyzing gene expression profiles from TCGA database with selected bioinformatics tools and methods. Tumor tissues from 81 cases with advanced and unresectable melanoma were collected for detecting HHLA2 and CD8 levels by immunohistochemistry.

Results

HHLA2 was found to be ubiquitously expressed in pan-cancer with high level and correlate with the prognosis of patients. Further comprehensive analysis from TCGA database demonstrated that the highly expressed HHLA2 was remarkably correlated with better prognosis, high infiltration status of various immune-active cells and immune activated pathways in skin cutaneous melanoma (SKCM). Moreover, immunohistochemistry (IHC) analyses of FFPE tissue from melanoma patients revealed that HHLA2 high expression was strongly related to improved response to ICB and indicated a longer progression-free survival (PFS) and overall survival (OS). Besides, HHLA2 expression was found to have a positive association with the density of CD8+ TILs.

Conclusion

Our findings revealed that high expression of HHLA2 has important values in predicting the response to ICB and indicating improved PFS and OS in patients with advanced and unresectable melanoma, suggesting that HHLA2 may serve as a costimulatory ligand in melanoma, which renders it as an ideal biomarker for immunotherapy.