bluuebunny/crossref_metadata_2025 huggingface dataset:
Features of the Impact of External Effects of Innovation and Innovative Entrepreneurship on Economic Growth and Development of Society
Authors: Kramchaninova Maiia D. ,   Volodymyr Dahl East Ukrainian National University, Kasatkina Maryna V. ,   Volodymyr Dahl East Ukrainian National University
Published: July 2024

The aim of the article is to determine the features of the relationship between innovative entrepreneurship and external effects arising from the introduction of innovations, from the standpoint of understanding under what conditions the losses that society bears, also the numerous complex risks from the introduction of innovations, can be acceptable, justified and properly compensated. In a complex, dynamic world, innovative technology and entrepreneurship play a crucial role in overall economic development. Along with this, the carried out study of many aspects of the impact of innovation and innovative entrepreneurship on economic growth and development of society has also revealed a significant number of negative external effects that arise at different economic levels and which today are almost not regulated. These external effects accumulate, transform, and give rise to other additional effects. Despite a large number of studies, various attempts by scholars to advance in the elimination of negative externalities have not yet provided an adequate organizational and methodological approach to such an internalization of these effects, which could be considered quite effective. Based on the analysis of scientific sources, one of the main reasons for the imperfect mechanism for eliminating the negative consequences of externalities of innovation activity is the insufficiency of the development of the taxonomy of externalities – due to the lack of progress in the establishment and distribution of property rights to external effects and the appropriate differentiation of possible types of externalities in terms of their significance and scale. The existing institutional possibilities of such regulation are not satisfactory and should be transformed in accordance with the new socioeconomic needs of society. The authors also note that due to the increased complexity and lack of a universal approach to the valuation of external effects, the development of an appropriate mechanism for regulating externalities actualizes the study of a broader issue of management accounting in the context of the above problem.
Research on Youth Awareness of Tools of Influence on Local Self-Government Bodies
Authors: Lola Yuliia Yu. ,   Simon Kuznets Kharkiv National University of Economics, Nesmiian Dmytro M. ,   Simon Kuznets Kharkiv National University of Economics
Published: July 2024

The article presents the results of a social study on the readiness of young people of the Kharkiv community to be involved in making socially important decisions under the influence of global crises. Three hypotheses have been proposed. First, global changes encourage a content-based transformation of civic values of student youth in Kharkiv towards their strengthening. Secondly, the dangers of wartime lead to an increase in the civic activity of young people in Ukrainian society. Thirdly, the level of civic education remains low. To evaluate the hypotheses put forward, the method of online survey of students and pupils of the Kharkiv community has been used. The results showed the following: 1) insufficient awareness of young people about the tools of influence on the authorities; 2) the farther the respondents are geographically, the more desperate they are in the possibilities of influencing local authorities; 3) a fairly high level of potentially active youth, since 28.2% of students and pupils feel empowered to take the initiative to interact with local governments. In addition, a high percentage of young people trust NGOs and consider them effective, and most of the students and pupils positively assess the democratic changes that have taken place in Ukrainian society (42.5% of students and schoolchildren positively assessed the results of the decentralization reform). Based on the results of the carried out social study, the importance of raising the education of young people regarding their influence on the government is emphasized, which is an important step for strengthening democracy and civic participation in community development. The findings of the social study of civic literacy of the youth of the Kharkiv community and the proposed recommendations actualize the discussion on the need to strengthen civic education and stimulate the activity of young people in interacting with the authorities and involving them in decision-making will be useful in finding ways to solve existing problems, ways to support the community in planning youth policy in the post-war period.
Methodological Approaches to Analyzing the Level of Territorial Development in Ukraine
Authors: Vasyliev Oleksii V. ,   Educational and Research Institute «Karazin Business School» of V. N. Karazin Kharkiv National University, Huriev Vladyslav O. , Uvarov Ihor S. ,   Educational and Research Institute «Karazin Business School» of V. N. Karazin Kharkiv National University,   Educational and Research Institute «Karazin Business School» of V. N. Karazin Kharkiv National University
Published: July 2024

The article examines methodological approaches to the analysis of the level of territorial development in Ukraine. The main approaches to the analysis of the level of territorial development, which are contained in official documents and serving as bases for development of methodological recommendations, are allocated, in particular: 1) methods of preparing a socioeconomic analysis of community development; 2) development of profiles of communities; 3) methods of formation and implementation of forecast and program documents of socioeconomic development of the united territorial community; 4) methodology for taking into account the Sustainable Development Goals in the development strategies of territorial communities. The territory as an object of development is considered from various aspects: economic, socio-cultural, ecological, and political. The concept of «territory» is usually associated with spatial characteristics and is considered as a limited part of the land surface with a certain area, geographical location and other spatial features. However, in the case of interpreting the territory as an object of development, this concept should be considered as a separate, identified by geospatial features and administrative subordination territory with the appropriate structure, conditions, properties and characteristics. The main principles on which methodological approaches to the analysis of the level of territorial development should be based are allocated, i. e.: consistency; integration; focus on the needs of the local community; public participation; scientificity; validity and objectivity; sustainability; rational use of resources; monitoring and evaluation. It is emphasized that in Ukraine there is currently no single methodological approach to the analysis of the level of territorial development, and the existing methods turned out to be imperfect and require revision. In particular, only certain methodologies of analyzing the level of territorial development are in use, as well as certain methods of taking into account the Sustainable Development Goals in the development strategies of territorial communities, although this does not comply with the principles of consistency, sustainability, and integration. The necessity of developing a unified methodological approach to the analysis of the level of territorial development in Ukraine, which would take into account a comprehensive analysis of the current state of territorial communities and the compliance of their development with the Sustainable Development Goals, is substantiated.
Use of Analysis and Control Methods in Due Diligence
Authors: Kopotiienko Tetiana Yu. ,   State University of Trade and Economics, Pavlov Vladyslav V. , Shyrchenko Bohdana S. , Lysyi Vitalii I. ,   International European University,   State University of Trade and Economics,   State University of Trade and Economics
Published: July 2024

Intensification of market processes in the part of attracting foreign investment, conducting mergers and acquisitions (M&A), restructuring of enterprises and expansion of their activities determines the importance of providing potential investors with high-quality information support for making strategic managerial decisions. A contemporary instrument for a comprehensive due diligence of the company’s activities is the audit service of «due diligence». The absent standardization and the lack of legal regulation of due diligence necessitated the improvement of the methodological instruments of this service. Based on this, it is expedient to use modern methods of analysis and control, which will allow not only to assess risks, but also to take preventive measures to minimize them. The aim of the article is to substantiate the content of «due diligence» and improve the methodological instruments by providing recommendations on the use of methods of analysis and control. The information basis of the present research is the normative legal acts of Ukraine on audit and accounting, scientific publications of scholars. The article applies general scientific and special research methods: induction, deduction, analysis, synthesis, horizontal analysis, comparison, and others. Due diligence – as a process of comprehensive preinvestment study – is a crucial element for successful risk management and achieving positive results from concluding an agreement. The dynamics of M&A transactions over the past decades in the world, as well as the structure of the largest contracts in Ukraine over the past year, are researched. Proposals for improving the methodological support for conducting the main types of due diligence based on the use of methods of analysis and control have been developed.
Analyzing the Volume of Export-Import Activity of the European Union Market
Authors: Chepeliuk Marharyta I. ,   Simon Kuznets Kharkiv National University of Economics, Melnik Yaroslav M. ,   Simon Kuznets Kharkiv National University of Economics
Published: July 2024

The article is devoted to a detailed analysis of the export-import activity of Ukraine in the markets of the European Union (EU), with an emphasis on fat-and-oil products. The full-scale invasion of Ukraine forced to strengthen economic ties with partner countries due to a decline in export-import operations. It is determined that the fat-and-oil industry is one of the key ones in the agro-industrial sector of the EU and plays an important role in ensuring the food security of countries. An analysis of the dynamics of exports and imports of margarine in the following EU countries: Poland, Slovakia, Hungary, Romania, and also taking into account Moldova, is carried out. The difference between the exports and imports of margarine in these countries has been established. As a result of the analysis of the volume of exports and imports of margarine, it is found that Slovakia, Hungary, Romania and Moldova are markets with a high level of import dependence in the margarine segment, which makes them the perspective ones for Ukrainian producers. An analysis of the dynamics of margarine imports in the EU countries for 2013–2021 showed the largest import volumes in the following countries: Great Britain, France, Germany and the Netherlands. To understand the specifics of this market, it is important to consider the numerous factors that affect supply and demand. Practical recommendations for entering the markets of the EU countries are provided, which include an assessment of the potential volume of sales, costs, investments and the availability of trained staff. It is also necessary to adapt products to European standards, develop effective marketing and distribution strategies. The study is an important contribution to understanding the dynamics of the EU markets and the development of strategies for entering them, contributing to the improvement of Ukraine’s export activities in the face of modern challenges.
Foreign Economic Activity of Enterprises: Modern Challenges and Prospects of Development
Authors: Kashperska Anastasiia I. ,   State Biotechnological University, Yatsiuk Oleh V. ,   State Biotechnological University
Published: July 2024

The aim of the article is to study the current state of foreign economic activity of Ukraine, to determine the prospects for development, taking into account the political and economic situation in the country. The article characterizes the current state of foreign trade. According to the State Statistics Service of Ukraine, the general indicators of foreign trade in goods in 2018–2024 are analyzed as follows: the total value of imported and exported goods, the volume of export-import operations, the commodity structure of foreign trade, and the geographical structure of foreign trade in goods. The main problems inherent in the economy of Ukraine are allocated, including: the continuation of the general slowdown in the growth rate of the world economy and the establishment of restrictive measures on Ukrainian exports of agricultural products used by the countries of the European Union. The main features and prospects for the development of the international trade market are defined, namely: improvement of the regulatory framework, updating the Association Agreement with the EU; ensuring predictable and stable terms of international trade; ensuring the possibility of transporting goods by railway; ensuring the competence of the economic entities engaged in foreign economic activity; increasing the procurement of licenses for the latest technologies; increasing the competitiveness of domestic manufacturing enterprises; improving the quality of Ukrainian goods and services; simplification of customs control. The most promising directions of foreign trade for Ukraine have been allocated, such as: the agricultural sector; IT sector; light industry and fashion; transport and logistics. It is emphasized that there is a general trend of prevalence of imports over exports throughout the study period, which justifies the expediency of establishing relations with existing partner countries and expanding and strengthening foreign cooperation in the field of trade.
World Experience in the Onboarding Processes: From Theory to Practical Implementation in Ukraine
Authors: Varis Iryna O. ,   Kyiv National Economic University named after Vadym Hetman, Kravchuk Oksana I. , Ivahnenko Krіstіna O. ,   Kyiv National Economic University named after Vadym Hetman,   Kyiv National Economic University named after Vadym Hetman
Published: July 2024

The aim of the article is to determine the importance of taking into account the experience of adaptation of personnel from other countries for Ukrainian companies in order to successfully function both in the international market and in Ukraine. The study identified common features of onboarding programs in different countries of the world, such as an emphasis on corporate culture, diversity, professional development, work-life balance, teamwork and communication. The unique features of the processes of personnel adaptation, characteristic of individual countries and due to cultural, historical, religious, legal and social factors, are identified. The importance of taking into account the experience of adaptation of personnel from other countries for Ukrainian companies is substantiated in view of active integration into the international environment, attraction of foreign specialists and expansion of international cooperation. The characteristic features of the process of adaptation of personnel in Ukraine, arising from the cultural, historical and social realities of the country, are determined. Aspects of personnel adaptation based on the experience of other countries, which can be implemented in Ukraine, are proposed. An indicative roadmap for the implementation of these features of personnel adaptation in Ukraine has been developed, taking into account the national context. Thus, the study provides a comprehensive analysis of the processes of personnel adaptation in the international context, identifies areas of improvement for Ukrainian companies and outlines the prospects for further scientific work in this area. Regarding the further scientific research, it is proposed to focus on an in-depth study of cultural, historical and social factors that affect the processes of personnel adaptation in Ukraine and other countries of the world; analyses of the efficiency of various methods and practices of personnel adaptation in specific organizations and industries; examining the impact of onboarding programs on staff retention, job satisfaction, and productivity; development of recommendations for adaptation and implementation of the world’s best practices of personnel adaptation in Ukrainian realities; studying the role of technology and innovative approaches in the process of personnel adaptation in the era of digital transformations.
Formation of a Competitive Position of Enterprise Based on the Principles of Digital Marketing
Authors: Naumenko Maksym A. ,   CO CF Ukrainians Together
Published: July 2024

Today, the domestic economy is facing significant problems caused by ongoing russian aggression. However, despite everything that has happened, there are still many competitive industries in the economy, where enterprises constantly compete for the attention of consumers, so the formation of an effective competitive position of the enterprise in the markets remains relevant for enterprises. The study analyzes the essence and features of the use of digital technologies in the marketing management of enterprises, the possibilities of their integrated interaction and complementation. The features of the main digital technologies used for positioning domestic and foreign enterprises in the markets are systematized and described. The conditions for their successful and expedient application for various managerial tasks are determined. It is found that the most common digital technologies that are successfully used in the practical marketing of enterprises are marketing analytics, affiliate marketing, content marketing, email marketing, PPC, SEO, mobile and social marketing. It is substantiated that the use of these technologies contributes to the generation of a number of positive effects for enterprise: communications between enterprises and consumers are improved; a positive image of the enterprise is formed; the efficiency of decision-making increases by obtaining better and more complete market information; it becomes possible to regulate the amount of costs for obtaining information, etc. The article also provides a comparative characteristic of digital technologies from the standpoint of their advantages and disadvantages in terms of fulfilling the tasks of market positioning of enterprises. A number of recommendations on how to improve the results of using some digital technologies, including email marketing, PPC, and SEO, have been formed.
The Industrial Parks of the Lviv Agglomeration: Status, Experience, Prospects
Authors: Zhabynets Olha Yo. ,   Institute of Regional Research named after M. I. Dolishniy of the NAS of Ukraine, Sukhyi Oleh O. ,   Ivan Franko National University of Lviv
Published: July 2024

The article is devoted to the study of the status and prospects for the development of industrial parks in the Lviv agglomeration, as well as the analysis of foreign experience in the functioning of industrial parks in agglomerations. The relevance of measures to implement the State Strategy for Regional Development for 2021–2027 regarding the support of territories such as agglomerations is argued, this is evidenced by the institutional arrangement of the Lviv agglomeration even in times of war. It is noted that when creating a modern model of reindustrialization in Ukraine with a focus on exports and in general an innovative ecosystem of agglomerations, the creation and development of industrial parks as modern concentrators of the industrial, investment and research potential of the agglomeration will be of paramount importance. Emphasis is placed on the advantages of the functioning of industrial parks within the agglomeration, in particular through: achieving synergy for the growth of economic development of the agglomeration; direct impact on the provision of humanitarian, environmental, security and spatial organization of the agglomeration; creation of the effect of increasing returns due to the effective combination of production and infrastructure, high technologies, research and development sphere. It is proved that the industrial parks of the Lviv agglomeration today are the least developed form of the innovation ecosystem of the agglomeration, the potential of which, unlike clusters or export enterprises of the agglomeration, has not yet been used at all. It is concluded that the institutional component of the development of industrial parks in Ukraine, and in particular within the Lviv agglomeration, should become a priority in the implementation of the State regional policy and strategies for the development of individual territorial communities in the near future. After all, foreign experience proves the close interweaving of urban agglomeration and its industrial parks, whose activities in Ukraine, even with the current institutional design, open up a promising environmentally oriented direction for them.
Experience and Enlightenment of Russian Water Right System
Authors: Wu Ting
Published: July 2024

This article provides a comprehensive overview of Russia's water resources, their development and utilization status, as well as the water rights system and related laws and regulations. It begins by detailing the abundant rivers, lakes, and groundwater resources in Russia. The analysis highlights that Russia has a high proportion of industrial water use, advanced water recycling technology, and significant water storage capacity in numerous reservoirs. The article also delves into the main contents of the Russian Federation Water Law, covering ownership and usage rights of water resources, and the legal responsibilities for water protection and management. Finally, it summarizes the experiences and insights from Russia's water rights system, emphasizing the importance of integrated basin management, clear water rights ownership, and the establishment of a comprehensive legal framework.
Influence of Key Shear Factors on the Shear Performance of Ultra-high Performance Fibre Reinforced Concrete Beam Containing Coarse Aggregate
Authors: Smith Abutu Simon John , Xu Gang
Published: July 2024

This paper assesses the effect of direct and indirect factors on the shear performance of ultra-high performance fibre reinforced concrete beam containing coarse aggregate (UHPFRC-CA) using four point loading arrangement. The obtained results were used to categorize UHPFRC-CA beam's failure mode, establish the influence of key factors on shear performance, and develop UHPFRC-CA beam's compression zone resistance and first shear cracking load equations whose results were compared with those from this research, other researchers and existing equation. Findings revealed that UHPFRC-CA beam fails in cable stayed, shear partial compression, cable stayed-diagonal tension and cable stayed-partial shear tension. Shear span-depth ratio (a/d) has the most influence on the beams' failure mode. Higher percentage volume of steel fibre improves ultimate load capacity and midspan displacement resistance at failure load. Hooked-end steel fibre improves deformation (crack width and midspan displacement at failure load) resistance. Higher a/d is more beneficial to midspan displacement resistance at failure load than load capacity; while lower stirrup spacing leads to higher midspan displacement at failure load. Finally, the developed first shear cracking load equation can adequately capture the true first shear cracking load of UHPFRC-CA beam; and the developed compression zone resistance equation can be conveniently used to represent the joint contribution of compressive strength and fibre factor to UHPFRC-CA beam's shear resistance.
The Prisca Theologia in the Early Reformation Debates
Authors: Tortoriello Giovanni
Published: July 2024

The paradigm of the prisca theologia, developed by Marsilio Ficino in the second half of the fifteenth century, had a huge influence throughout the early modern period. Its influence on the Reformation debates, however, has not yet been investigated. In the present article, I make an initial contribution to filling this gap. In the first part, I show that theprisca theologia was widely disseminated in the territories of the Holy Roman Empire at the beginning of the sixteenth century, including at the University of Erfurt where Martin Luther was educated. In the second half, I focus on two figures central to the Reformation debates: Johann Eck and Martin Luther. As I show, Eck had an ambivalent attitude towards theprisca theologia: on the one hand, he aimed to reconcile the scholastic tradition with the ancient doctrines of theprisci theologi; on the other hand, he distanced himself from the Hermetic and magical implications of theprisca theologia. Luther, meanwhile, developed an anti-paradigm to Ficino’s prisca theologia: he argued that the improper mixing of black and white magic was born in Persia and then developed in Egypt and Greece.
Literature Review: Development of Electronic Medical Records In Hospital Management Information Systems
Authors: Yudhistira Dhau 'Atha , Ernawaty Ernawaty , Pratami Nadena Majeda Dien
Published: July 2024

Introduction: Health technology today is developing very quickly from the initially conventional using paper to being computerized. This literature review aims to map and critically summarize the scientific evidence on the cost-effectiveness and acceptability of Computerized Physician Order Entry (CPOE) and Electronic Health Reports. This Journal have Question that need to be answered how does the development of CPOE in medical records affect cost-effectiveness improvement so that it can be accepted by many parties? Method used in this journal is literature review is conducted on journal articles related to costs and receipts in CPOE. The systematic search was conducted from 5 databases namely PubMed, Science Direct, ProQuest, DOAJ and Ebscohost. Journal articles are selected and selected following PRISMA guidelines. Twenty-five journal articles qualified based on predetermined criteria. At the end as result, Cost-effectiveness with CPOE is more likely to be found that it is easier to reach compared to conventional methods. In addition, the acceptance of patients and health workers is also high. These factors can have a positive or negative influence on the hospital management system because developing countries still need adequate resources so that they can run these methods. Discussion and conclusion CPOE systems can improve patient safety by detecting drug interactions and actions. It is necessary to develop medical records in order to provide effective financing and acceptance.
Sentiment Analysis of Public Responses on Social Media to Satire Joke Using Naive Bayes and KNN
Authors: Putra Selian Rasyid Ihsan , Vitianingsih Anik Vega , Kacung Slamet , Lidya Maukar Anastasia , Febrian Rusdi Jack
Published: July 2024

This study examines the use of Satire Joke as a humorous communication style in conveying criticism of the government through social media. Satire Joke is often used to depict the government's inability to address important social issues, such as slow bureaucratic processes and unfulfilled political promises. The aim of this research is to analyze public sentiment towards Satire Joke expressed on the YouTube social media platform. The methods used in this study are Naïve Bayes and K-Nearest Neighbors (KNN) due to their effectiveness in data classification. The results of this study are expected to help gain an understanding of social issues for the community and public knowledge. This research is also expected to contribute to the development of sentiment analysis methods in the future. The analysis results show that 400 data have neutral sentiment, 850 data have negative sentiment, and 947 data have positive sentiment. Based on testing, both Naive Bayes and KNN methods show good performance. The Naive Bayes method achieved the best accuracy of 90.29%, while the KNN method achieved an accuracy of 60.75%.
Decision Support System for Selecting Online Teaching Methods Using the Fuzzy MCDM Algorithm
Authors: Marsono Marsono , Nasyuha Asyahri Hadi , Syahra Yohanni
Published: July 2024

The global pandemic that has hit the world recently has forced educational institutions to adopt online teaching methods. However, choosing an effective online teaching method is a major challenge. This research develops a Decision Support System (DSS) that uses the Fuzzy Multi-Criteria Decision Making (FMCDM) Algorithm to select the best online teaching method. This system is designed to assist decision making in educational institutions by considering various criteria such as learning effectiveness, technology affordability, ease of use, and user satisfaction. This research uses data collection methods that involve surveys from lecturers and students to obtain their preferences and experiences with various online teaching platforms. The data collected is then processed using the FMCDM model to evaluate and rank teaching methods based on predetermined criteria. Fuzzy systems are used to overcome uncertainty and subjectivity in criteria assessment. The results of this research show that the system developed is able to effectively assess and rank various online teaching methods. From the analysis carried out, interactive teaching methods using videos and real-time quizzes received the highest ranking based on predetermined criteria. This suggests that the combination of engaging visual content and high interactivity is highly valued in online teaching contexts
Student Organization Website with E-Voting Feature by Using Student Card Verification Concept Design
Authors: Paskalis Yohanes Maria Jonathan Glenn , Bachri Karel Octavianus
Published: July 2024

Student organizations hold an election to decide their next head and vice head every year. The best voting method for student organizations is to use an independent website with a voting system. The voting system can use students’ identity card and their student email as base for verification. OCR and face detection can be used for extracting all the needed information to validate the student card and verify it with the corresponding student email input. Other than the voting system, the website can be used to promote the student organization itself. The website was built using Nuxt for its front-end, Firebase for its back-end, and Cloud Vision API for its OCR and face detection module. There is a Lighthouse test, a stress test for the voting system, and a test to determine the optimal file size for the voting system. The results are a website that has an average Lighthouse score of 97.58. The stress test, which used a script that does submission repeatedly, results suggest that the voting system can handle up to 2000 voters at the same time. The optimal file size determined by the authors to be 500KB as the result of its test. The conclusions are a great performing website with a voting system can be built using Nuxt and Firebase, the voting system can be improved by adding another step of verification, and it’s best to use and image with a file size above 250KB when using Cloud Vision API for optimal results
Indonesians Perception on the South China Sea Dispute: Support Vector Machine and Naïve Bayes Approach
Authors: Hafizha Adinda Aulia , Nidatya Nurfarah
Published: July 2024

In recent years, relations between Indonesia and China have become increasingly cordial. However, a potential source of tension is emerging in the form of a heightened dispute in the South China Sea. The government of Indonesia is considered an ally, however there has been a long-standing negative opinion among Indonesians regarding China, which has influenced the way both the general public and the political elite have perceived the relations between Indonesia and China. This research has two objectives. The first is to examine Indonesian perceptions regarding the South China Sea conflict. The second is to compare the performance of Support Vector Machine (SVM) and Multinomial Naïve Bayes as a method of sentiment analysis. Using 7.051 Indonesian-language posts from social media X as a dataset, the result shows that a significant portion of Indonesians view the dispute negatively, fearing potential escalation and threats to national security. Despite these concerns, there is reason to believe that Indonesia can play a proactive role in resolving the conflict through ASEAN and UNCLOS frameworks. Meanwhile, SVM has been demonstrated to be an effective method for handling sentiment analysis data, achieving an accuracy of 87.95%. This work contributes to the field of sentiment analysis by highlighting social media as a valuable platform and by demonstrating the effectiveness of SVM. Furthermore, the study offers new insights for the field of international relations by analyzing the South China Sea dispute through a machine learning lens, which may lead to the development of novel perspectives.
Usability Testing of Industrial Engineering UPNVJT Website Using Eye Tracking and System Usability Scale
Authors: Dicya Bintara Putra , Tranggono Tranggono
Published: July 2024

Websites are essential for agencies and organizations to ensure their information is accessible to the public. The eye tracker method is effective for evaluating user usability. The Industrial Engineering Study Program at Universitas Pembangunan Nasional "Veteran" East Java has an official website, tekindustri.upnjatim.ac.id, which has not been tested for usability. Initial problem identification revealed issues such as inaccessible menus and hidden information. This study aims to assess and improve the user experience on the website using a combination of Eye Tracking and System Usability Scale (SUS) methods. The average effectiveness score for 39 respondents is 89.10%, with 8% rated as ineffective, 28% as effective enough, and 64% as very effective. The efficiency value, measured across 39 respondents and 4 tasks, is 0.0276 goals/second, indicating each respondent completes 2.76% of tasks per second, requiring about 36.23 seconds to reach 100% task completion. The initial SUS score was 69.49%. Five issues were identified in the Home, Facilities, Education, Thesis, and MBKM sections and one design issue. A prototype was developed and tested, resulting in a final SUS score of 80.06%, placing the website in the marginally high acceptability range, category B for grade scale, and excellent for adjective ratings. The SUS score improvement was 10.57%. This research shows that combining Eye Tracking and SUS is an effective method for increasing website usability. The implications of this research can help organizations improve the quality of their websites and provide a better user experience.
DV in International Households in Japan: Interview and Questionary Survey Results on Cases of Sexual Violence
Authors: Lukyantseva Polina
Published: July 2024

This study investigates instances of sexual violence within international households in Japan consisting of one Japanese and one non-Japanese citizen. By applying two classifications such as relationship violence (i.e., intimate partner mistreatment) and type of maltreatment (in the case of this study, it is sexual violence), the research explores intimate partner violence and sexual coercion and abuse. The reliable data was collected from 83 survey participants and 18 interviewees, revealing that most respondents either did not experience or were unwilling to disclose incidents of sexual mistreatment. According to the OEQ, three participants reported instances of sexual abuse. With the consent of two female respondents, their experiences were analyzed using inductive coding and case study methods and illustrated in this manuscript. The findings highlight significant obstacles, including the lack of research and statistical data on domestic violence in international households in Japan. Despite these challenges, the study elucidates the nature of sexual domestic violence and abuse faced by migrants. It underscores how environments of fear and male dominance affect women's control over their fertility and sexual freedom. The case studies illustrate different forms of reproductive control and forced sex, suggesting a need for further research on sexual abuse as a risk factor for sexual coercion, fertility control issues, and the potential spread of HIV and other sexually transmitted diseases in international households.
Increased temperatures impact the reproduction of localized estuarine kelp populations more than salinity or invasive species
Authors: Korabik AR , Dias SM , Grisby GV , Grosholz ED
Published: July 2024

Estuarine habitats regularly experience large variations in abiotic conditions such as temperature and salinity; however, under climate change and the increasing threat of invasive species, the pressure from both abiotic and biotic stresses has been increasing. Several studies have investigated the interactions of the adult stages of macroalgae; however, there is little understanding of how microscopic stages of Macrocystis pyrifera and Sargassum muticum interact or how climate change may influence this interaction. Our research considers the effects of climate-driven changes in temperature and salinity and their interactions with S. muticum on the growth and survival of M. pyrifera gametophytes from Tomales Bay, CA, USA. Using kelp culturing experiments, we tested (1) how different salinities and temperatures impact early life stages M. pyrifera from different sources within Tomales Bay, (2) how the presence of invasive S. muticum propagules affect M. pyrifera gametophyte development, and (3) how the combined effects of salinity, temperature, and S. muticum presence affect M. pyrifera early life stages. Our results suggest that M. pyrifera may be able to adapt to local conditions like salinity; however, higher temperatures from a changing climate and the presence of competitors from biological invasions act additively, but not interactively, to negatively impact the early life stages of kelp. By determining how foundation species respond to various abiotic and biotic stressors, we can better predict how these species will perform in a changing environment and how they will contribute to overall ecosystem resilience.
Variation in top-down control of red algae epibiosis in the White Sea
Authors: Chava A , Artemieva A , Yakovis E
Published: July 2024

Epibiosis is shaped by a complex interplay of biotic interactions involving hosts, epibionts, and mobile consumers. In temperate waters, consumer control by mesograzers prevents complete overgrowth of seaweeds. In polar waters, the mechanisms determining the abundances of sessile organisms associated with seaweeds are unknown. We empirically assessed the strength of the consumer control effect on the colonization of the sub-arctic red seaweed Phycodrys rubens by caging individual plants in the field in the shallow subtidal of the White Sea (65°N). We compared epibiosis on plants in consumer exclosure cages, in cages with the mesopredatory shrimp Spirontocaris phippsii, in semi-enclosed cages, and on unmanipulated plants in a cold year (2014) and a warm year (2015). Despite the dramatic interannual variation in consumer control, the mean total cover of epibionts in the absence of consumers never exceeded 15%. While consumers had a substantial effect on the total epibiont cover in the warm year and a nearly negligible effect in the cold year, the total cover of unmanipulated algae was similar in 2014 and 2015. Bryozoans, which were selectively impacted by consumers—particularly shrimp—dominated in both years. However, bryozoan abundance was much lower in 2015, when the abundance of hydroids, sponges, and bivalves—less affected by consumers—increased. Consumer control is not a key factor preventing most Phycodrys plants from being heavily overgrown. Yet, smaller plants, which have a higher epibiont cover, may indirectly benefit from consumers. Future climate changes are likely to make the Phycodrys epibiosis increasingly top-down regulated.
Overcoming challenges in advanced melanoma treatment
Authors:   , van Not Olivier Jules
Published: July 2024

Each year, approximately 800 to 900 patients in the Netherlands are diagnosed with metastatic (i.e. unresectable) melanoma.
Several new systemic therapies have become available for the treatment of unresectable melanoma. These therapies, including targeted therapy and immune checkpoint inhibitors, have significantly improved survival. However, several challenges remain in the treatment of this disease.
Using data from the Dutch Melanoma Treatment Registry, this dissertation addresses some of these challenges. It describes research on changes in the treatment landscape of unresectable melanoma, on the optimization of the treatment of unresectable melanoma, and on specific subgroups of patients.
COVID-19 has had a significant impact on melanoma care in the Netherlands. Nevertheless, the survival of patients with unresectable melanoma has improved over the years. We also observed that a portion of patients experience long-term survival after treatment with immune checkpoint inhibitors. Furthermore, we found that retreatment of patients with targeted therapy, after previous treatment with targeted therapy, results in a response in 43% of patients.
Additionally, we investigated how the treatment of severe adverse events caused by immune checkpoint inhibitors affects survival. Lastly, this dissertation describes the results of the treatment of patients with both unresectable melanoma and a hematological malignancy, the treatment with immune checkpoint inhibitors of patients with melanoma brain metastases, the treatment of patients with acral melanoma, and the influence of having a BRAF or NRAS mutation on the response to immune checkpoint inhibitors.
Formulación analítica para el cálculo de tableros bijácena con solicitación excéntrica
Authors: HENCHE BLANCO JAVIER
Published: July 2024

Se presenta un planteamiento analítico para la obtención de las deformaciones y solicitaciones en tableros con vigas gemelas, en especial los obtenidos a partir de secciones prefabricadas en artesa. Fue de inspiración y fundamento, la fuerza de la descomposición de la función resistente en estados más simples, para la obtención de una formulación matemática. Se trata de una forma similar al planteamiento que realizó Javier Manterola en el memorable articulo “La sección abierta y cerrada bajo solicitación excéntrica” [1]. Para la resolución se efectuará una aproximación al formalismo matemático de las funciones de Green. El planteamiento requiere una serie de simplificaciones  admisibles que aproximan con bastante rigor la solución, y permiten la evaluación directa de la acción de cargas móviles. Por último, se efectúa un análisis de la efectividad del reparto transversal conseguido con diversas condiciones de apoyo.
“Burning scalp” syndrome: relevance, place in clinical taxonomy and therapeutic approaches
Authors: Lvov A. N. , Levina A. D. , Skandaryan A. A.
Published: July 2024

One of the sensitive skin types is the “burning scalp” syndrome. It is the most expressed subjective symptom complex of tactile sensations in the projection of the skin of the scalp. The most common manifestations of this syndrome, which significantly reduces the quality of patient’s life, are burning, itching, pain, trichodynia, redness like flushing and persistent erythema, mild exfoliation and hair loss sometimes. The “burning scalp” formation is heterogeneous and can be associated with comorbid dermatoses (seborrheic dermatitis, eczema, atopic dermatitis, psoriasis, rosacea, fungal and bacterial contamination, alopecia, etc.), organ and visceral pathology (diabetes mellitus, multiple sclerosis, tumors of the central nervous system, paraneoplastic conditions, immunodeficiencies, etc.), psychosomatic abnormalities (conversion disorders, sensory hypochondria, somatoform pruritus) and environmental influences (aquagenic pruritus, ultraviolet radiation). Now, there are no general recommendations for the “burning scalp” treatment. For long-term accompanying treatment and prevention, therapeutic cosmetics that normalize the microbiome and have antipruritic and anti-inflammatory effects are promising.
Using the Height-for-Age Z-score (HAZ) to predict protein-energy malnutrition in patients with congenital epidermolysis bullosa through the application of machine learning methods
Authors: Orlova O. S.
Published: July 2024

Congenital epidermolysis bullosa (СЕВ) is a group of genetically and clinically heterogeneous diseases characterized by a tendency to form blisters and/or erosions on the skin and mucous membranes with minimal trauma. Nutritional deficiency stands as the most common complication observed in EB, with its development influenced by a multitude of contributing factors.

Purpose of the study. To construct a predictive model for the development of protein-energy malnutrition in patients with various forms of EB, identify the main features affecting the sensitivity of the predictive model, and evaluate the model’s validity based on retrospective data on the presence of protein-energy malnutrition in this patient category.

Methods. The study involved 101 patients aged 3 to 18 years with simplex (n=25), junctional (n=10), and dystrophic (n=66) СEB. The Birmingham EB Severity Score, laboratory and anthropometric parameters, as well as data on the presence of gastrointestinal complications, were used for the analysis of disease progression and predictive model construction. The Scikit-learn library of the programming language Python was utilized for building the machine learning model.

Results. In the construction of the predictive model, the RandomForestClassifier model showed the best results. The developed machine learning model can correctly determine whether a patient has chronic protein-energy malnutrition (class 1, HAZ < –2) or not (class 0, HAZ > –2) with an accuracy of 92%, sensitivity of 85.7%, and specificity of 100%.

Conclusions. The machine learning model presented in this study predicts the values of the Height-for-Age Z-score (HAZ) and can have practical significance in medical practice and clinical research. The model can be used for early diagnosis of protein-energy malnutrition in patients with EB, which may allow healthcare professionals to timely start nutritional support and prevent possible complications of the disease, as well as develop individual nutrition and treatment plans for patients.
Trifarotene, a retinoid of the fourth generation, in the treatment of acne: the first experience of use in a real clinical practice
Authors: Kruglova L. S. , Mayransaeva S. R. , Gryazeva N. V.
Published: July 2024

The article presents data on the local retinoid of the fourth generation trifarotene. The results of three large trials have been presented, which have proven good efficacy and long-term safety of monotherapy of the drug trifarotene in patients with moderate acne and in patients with severe acne for combination therapy. It has been shown that trifarotene demonstrates high selectivity to retinoic acid receptors RAR-γ, which are predominant in the skin, which provides clinical efficacy in low concentration and good tolerability.