bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Genome-Wide SSR Markers in Leymus chinensis with Genetic Diversity Analysis and DNA Fingerprints
Authors: Ou Taiyou , Wu Zinian , Tian Chunyu , Yang Yanting , Gong Wenlong , Niu Jianjiang , Li Zhiyong
Published: January 2025

Leymus chinensis, a major component of the plant community in the eastern Eurasian grasslands with a wide distribution, provides stability to grassland ecosystems and supports animal husbandry. This study aimed to bridge the gap between the molecular breeding and industrial application of L. chinensis by conducting a comprehensive simple sequence repeat (SSR) analysis. A total of 973,129 SSRs were identified in the L. chinensis whole genome, which was used to design 20 polymorphic pairs of SSR primers to further assess 105 L. chinensis accessions. On average, 33.55 alleles were detected per locus, with an average Shannon index of 2.939 and a polymorphic information content value of 0.910. Principal coordinate, maximum likelihood, and structure analyses consistently showed that all samples were coincidentally divided into four subclasses. In addition, Mantel test data indicated a weak correlation between genetic and geographical distances in L. chinensis, whose variability may be related to the pollination mode and natural selection pressures. Finally, we used the 20 pairs of selected markers to scan 105 accessions, constructing a fingerprint for them. These findings provide new foundations for identifying superior varieties, improving the management of genetic resources, and constructing a germplasm resource database for L. chinensis.
Genome-Wide Identification and Analysis of Carbohydrate-Binding Modules in Colletotrichum graminicola
Authors: Wang Ya-Fei , Huang Qiu-Li , Chen Xin-Yu , Li Hong-Lian , Chang Jia-Xin , Zhang Yu , Wang Yi-Wen , Shi Yan
Published: January 2025

Colletotrichum graminicola is the causative agent of both maize stem rot and leaf blight, which are among the most damaging diseases affecting maize. Carbohydrate-binding modules (CBMs) are protein domains that lack catalytic activity and are commonly found alongside carbohydrate-hydrolyzing enzymes in fungi. A comprehensive examination of the C. graminicola TZ-3 genome resulted in the identification of 83 C. graminicola CBM (CgCBM) genes, which are characterized by distinct gene structures and protein motifs. Subcellular localization analysis revealed that the majority of CgCBM proteins were localized in the extracellular space. Investigation of the promoter regions of CgCBM genes uncovered a variety of responsive elements associated with plant hormones, including abscisic acid and methyl jasmonate response elements, as well as various stress-related response elements for drought, cold, defense, and other stress factors. Gene ontology analysis identified the primary functions of CgCBM genes as being linked to polysaccharide metabolism processes. Furthermore, the 83 CgCBM genes exhibited varying responses at different time points during C. graminicola infection, indicating their contribution to the fungus–maize interaction and their potential roles in the fungal pathogenic process. This study provides essential insights into CgCBMs, establishing a crucial foundation for further exploration of their functions in the mechanisms of fungal pathogenicity.
Green and Efficient Extraction of Taraxacum kok-saghyz Natural Rubber and Its Structural Analysis
Authors: Zheng Jiagang , Zhang Fuquan , Zhao Qingyun , Yu Rentong , Zhao Yanfang , Liao Xiaoxue , Liao Lusheng
Published: January 2025

Natural rubber (NR) is in high demand due to its excellent elasticity and physical and mechanical properties, but production is limited and NR is in short supply. There is an urgent need to find new alternative rubber sources. Taraxacum kok-saghyz (TKS), as a green, renewable, widely planted and high content rubber producing plant, has shown broad application prospects. The extraction process is the key to developing efficient, green, and high-purity Taraxacum kok-saghyz Natural Rubber (TKNR) to replace NR in various applications. In this study, TKS roots were processed through repeated boiling to remove inulin, followed by alkaline treatment with potassium hydroxide (KOH) to isolate lignin and facilitate cell wall disruption. Subsequent enzymatic hydrolysis using pectinase and cellulase enabled the dissolution of root-structure carbohydrates, thereby obtained TKNR. Structural characterization of TKNR was conducted and compared with that of NR. The results showed that the combined alkaline and enzymatic extraction methodology effectively isolates TKNR from TKS roots. Structural analysis reveals that TKNR closely resembles NR, having comparable molecular weight and distribution, crystallinity, and crosslinking networks, with both polymers primarily consisting of cis-1,4-polyisoprene.
Progress in African Swine Fever Vector Vaccine Development
Authors: Yang Yue , Yuan Hengxing , Zhang Yulu , Luan Ji , Wang Hailong
Published: January 2025

African swine fever (ASF) is a highly lethal, infectious, hemorrhagic fever disease, characterized by an acute mortality rate approaching 100%. It is highly contagious, and results in significant losses to the global hog industry as it spreads. Despite incremental progress in research on the African swine fever virus (ASFV), a safe and effective commercial vaccine has yet to be developed. Vector vaccines, a promising type of vaccine, offer unique advantages, and are a primary focus in ASFV vaccine research. This paper focuses on the characteristics of viral, bacterial, and yeast vector vaccines; elucidates the immunological mechanisms associated with antigens; lists the types of antigens that have significant potential; discusses the feasibility of using exogenously expressed cytokines to enhance the protective power of vector vaccines; and, finally, discusses the types of vectors that are commonly used and the latest advances in this field.
Exploring the Behavior and Performance of Large Language Models: Can LLMs Infer Answers to Questions Involving Restricted Information?
Authors: Cadena-Bautista Ángel , López-Ponce Francisco F. , Ojeda-Trueba Sergio Luis , Sierra Gerardo , Bel-Enguix Gemma
Published: January 2025

In this paper various LLMs are tested in a specific domain using a Retrieval-Augmented Generation (RAG) system. The study focuses on the performance and behavior of the models and was conducted in Spanish. A questionnaire based on The Bible, which consists of questions that vary in complexity of reasoning, was created in order to evaluate the reasoning capabilities of each model. The RAG system matches a question with the most similar passage from The Bible and feeds the pair to each LLM. The evaluation aims to determine whether each model can reason solely with the provided information or if it disregards the instructions given and makes use of its pretrained knowledge.
Unraveling Cyberbullying Dynamis: A Computational Framework Empowered by Artificial Intelligence
Authors: Barbosa-Santillán Liliana Ibeth , Guzman-Velazquez Bertha Patricia , Orozco-Aguilera Ma. Teresa , Flores-Pulido Leticia
Published: January 2025

Cyberbullying, which manifests in various forms, is a growing challenge on social media, mainly when it involves threats of violence through images, especially those featuring weapons. This study introduces a computational framework to identify such content using convolutional neural networks of weapon-related images. By integrating artificial intelligence techniques with image analysis, our model detects visual patterns associated with violent threats, creating safer digital environments. The development of this work involved analyzing images depicting scenes with weapons carried by children or adolescents. Images were sourced from social media and spatial repositories. The statistics were processed through a 225-layer convolutional neural network, achieving an 86% accuracy rate in detecting weapons in images featuring children, adolescents, and young adults. The classifier method reached an accuracy of 17.86% with training over only 25 epochs and a recall of 14.2%. Weapon detection is a complex task due to the variability in object exposures and differences in weapon shapes, sizes, orientations, colors, and image capture methods. Segmentation issues and the presence of background objects or people further compound this complexity. Our study demonstrates that convolutional neural networks can effectively detect weapons in images, making them a valuable tool in addressing cyberbullying involving weapon imagery. Detecting such content contributes to creating safer digital environments for young people.
Insights into Contribution of Active Ceria Supports to Pt-Based Catalysts: Doping Effect (Zr; Pr; Tb) on Catalytic Properties for Glycerol Selective Oxidation
Authors: Rinaudo Matías G. , Yeste Maria del Pilar , Vidal Hilario , Gatica José M. , Cadús Luis E. , Morales Maria R.
Published: January 2025

How important is the support during the rational design of a catalyst? Herein, doped ceria (Zr; Pr and Tb) was used as an active support to prepare Pt catalysts (0.5 wt%) for glycerol selective oxidation. A thorough characterization of achieved catalytic systems showed that the nature of doping elements led to different physicochemical properties. The presence of surface Pr3+ and Tb3+ not only increased oxygen vacancies but also electron mobility, modifying the oxidation state of platinum particles. The redox properties of the catalyst were also affected, achieving a close interaction between the support and metal particles even in the form of Pt-O-Pr(Tb) solid solutions. Furthermore, the combination of medium-sized metal particle dispersion, strong metal–support interaction and a synergy between the amount of oxygen vacancies and Pt0, observed in the Pt/CeTb catalyst, led to a high turnover frequency (TOF) and increased selectivity to glyceric acid. Thus, the present study reveals how a simple structural modification of active supports, such as cerium oxide, by means of doping elements is capable of improving the catalytic performance during glycerol selective oxidation, avoiding the cumbersome methods of synthesis and activation treatments.
Cost-Effective Monitoring of Spruce Budworm Larvae
Authors: Rhainds Marc , Therrien Pierre
Published: January 2025

The spruce budworm, Choristoneura fumiferana Clem. (Lepidoptera: Tortricidae), is the most severe defoliator of balsam fir (Abies balsamea) in eastern Canada and northeast U.S.A. A large budworm outbreak is currently underway in the province of Québec, with 10.5 million hectares defoliated in 2023, up 14.1% from the year before. Populations of budworms are controlled using management guidelines of Forest Protection Strategy (FPS); the approach aims at killing defoliating larvae with aerial application of microbial insecticide, with the objective to limit defoliation and prevent tree mortality. The decision to treat/not treat a given forest block is based, in part, on local density of overwintering second instars (L2) collected at ca. 600 sampling points each year across the entire province at a cost of CAD 350 for three branches per site; the threshold for FPS (TFPS) corresponds to 20 L2/branch. Aerial defoliation maps also guide management decisions because FPS generally target areas within or in the vicinity of defoliated forest stands. Budworm abundance rapidly declines with distance to aerial defoliation (in km), to the extent that larval density rarely attains TFPS outside the core range of FPS (>15 km from defoliation). A cost-effective monitoring approach is proposed whereby forest blocks outside the core range of FPS are sampled every second year (as opposed to every year), representing a potential economy of CAD 40,000 annually.
Temperature Control During Storage of Raw Materials in the Process of Biodiesel Fuel Production
Authors: Eremeeva Anzhelika M. , Ilyushin Yury V.
Published: January 2025

In the modern conditions of the growing consumer market for environmentally friendly industries, the issue of optimizing resource-intensive and energy-intensive technological chains is acute. One of the most expensive stages is the storage of grain—raw materials for the production of biodiesel. This is due to there being no unified temperature control system. In this paper, the authors have developed a mathematical model and a hardware–software complex that allows for the measurement of the temperature field in grain storage areas. To address this challenge, the authors employed methodologies derived from spatial distributed systems to construct a mathematical model. The development of a technical device and the implementation of a software module for processing the measured data in C++ Builder were then undertaken.
How to Approach Left Ventricular Hypertrabeculation: A Practical Guide and Literature Review
Authors: Alfieri Michele , Principi Samuele , Barbarossa Alessandro , Stronati Giulia , Antonicelli Roberto , Casella Michela , Dello Russo Antonio , Guerra Federico
Published: January 2025

Left ventricular hypertrabeculation is one of the most debated conditions in modern cardiology. Many studies have tried to characterise this disease by addressing the various clinical risks and diagnostic tools, but its very nosological existence is currently being challenged. The latest ESC guidelines on cardiomyopathies state that it should be addressed as a morphologic trait rather than an intrinsic disease of the cardiac muscle. Despite the huge number of diagnostic criteria and possible phenocopies, no specific consensus identifies a specific flowchart regarding the management of patients with suspected hypertrabeculation. This review aims to provide a clinical approach for patients with a phenotypical appearance of excessive trabeculation.
Nutritional Status and Information Provided to Polish Cancer Patients Assessed Using the EORTC QLQ-INFO25 Questionnaire
Authors: Gliwska Elwira , Głąbska Dominika , Zaczek Zuzanna , Sobocki Jacek , Guzek Dominika
Published: January 2025

Background/Objectives: Malnutrition in cancer patients may significantly affect various aspects of the quality of life, outcomes, and prognosis, while satisfaction with the information provided may also influence these aspects. This study aims to assess the nutritional status of Polish cancer patients and its association with the level of information received, their potential need for more information, and the resultant quality of life. Methods: A cross-sectional study was conducted in 104 cancer patients. Validated European Organization for Research and Treatment of Cancer questionnaires EORTC QLQ-C30 and EORTC QLQ-INFO25 were used, and nutritional assessment was conducted using Subjective Global Assessment (SGA). Results: Male patients reported receiving more information than females about the disease, treatment, and care options, as well as greater satisfaction, and a higher overall score. Patients receiving enteral nutrition were more satisfied compared to those not receiving it, even if the scores for the information obtained within the specific areas did not differ, but they still wished to receive more information. Older patients reported higher scores than younger patients, indicating a higher level of information received regarding medical tests and higher satisfaction. The EORTC QLQ-INFO25 global score showed strong or moderate positive correlations with the majority of modules, and the level of information provided significantly influenced satisfaction. Conclusions: Female patients, those not receiving enteral nutrition, and young patients were less satisfied with the information received, which may negatively influence their quality of life. Effective communication with patients highlights the need for personalized informational support to enhance quality of life.
Evolution and New Perspectives of Balloon Pulmonary Angioplasty in CTEPH
Authors: Larsen Julia , Lakhter Vladimir , Nasri Amine , Bashir Riyaz
Published: January 2025

Chronic thromboembolic pulmonary disease (CTEPD) and chronic thromboembolic pulmonary hypertension (CTEPH) are debilitating complications of acute pulmonary embolism (PE) that are characterized by fibrosis and organization of the thrombotic material within pulmonary artery branches. This pathology leads to increased right ventricular afterload and dead space ventilation, posing a risk of progressive pulmonary hypertension, right-sided heart failure, and potentially death if left untreated. Pulmonary endarterectomy (PTE) is a technically complex open-heart surgery considered to be a first-line treatment as it is a potentially curative therapy. Although PTE is highly successful in proximal disease, it may not reach the very distal branches. On the other hand, pulmonary vasodilator therapy is very effective in improving microvasculopathy but does not address the obstructive fibrotic component of the larger vessels. Balloon pulmonary angioplasty (BPA) is a novel percutaneous revascularization therapy in which traditional angioplasty techniques are used to relieve obstruction in the pulmonary arteries. This review discusses the currently accepted indications, patient selection, technical considerations, outcomes, and complications of contemporary BPA. This review will address knowledge gaps and future perspectives in BPA research.
The Validation of the Perinatal Post-Traumatic Questionnaire in the Italian Population: Risk and Protective Factors
Authors: Nardozza Odette , Passaquindici Ilenia , Persico Melba Emilia , D’Andrea Antea , Suttora Chiara , Fasolo Mirco , Spinelli Maria
Published: January 2025

Background: Postpartum Post-Traumatic Stress Disorder (P-PTSD) symptoms develop after experiencing childbirth as traumatic. Several individual and environmental factors influence the childbirth experience. However, in Italy, this phenomenon remains unexplored due to the lack of screening tools. This project aims to validate the Italian version of the Perinatal PTSD Questionnaire (PPQ-II) and to identify maternal, pregnancy, childbirth, and postpartum risk and protective factors associated with P-PTSD. Methods: A total of 702 women (6–24 months postpartum) participated in an online cross-sectional study. They completed the PPQ-II, Depression Anxiety Stress Scales-21 (DASS-21), Big Five Inventory-10 (BFI-10), and a questionnaire to assess sociodemographic and perinatal factors. Factor structure was estimated with an exploratory (EFA) and confirmatory factor analysis (CFA). Internal consistency of the scale, convergent and divergent analyses were computed. Associations between perinatal factors and P-PTSD were also investigated. Results: The EFA revealed a two-factor structure: “Arousal and Mood alteration” and “Avoidance and Intrusion”. CFA supported the factor structure, showing a good fit of the data. The validity was confirmed by a significant association between the PPQ-II and the DASS-21 and a lower correlation with the BFI-10. Significant associations were found between P-PTSD symptoms and factors across the maternal, pregnancy, childbirth, and postpartum periods. Conclusions: The Italian PPQ-II is a valid screening tool to include in maternity care protocols for the early identification of P-PTSD. This study also contributes to identifying perinatal factors for symptom detection and the promotion of maternal well-being.
Increasing Importance of Genotype–Phenotype Correlations Associated with Common and Rare MEFV Gene Mutations in FMF Patients in the Last Thirty Years
Authors: Yildirim Sema , Bekis Bozkurt Hayrunnisa , Erguven Muferet
Published: January 2025

Background/Objectives: Studies have shown that some mutations, especially M694V, are correlated with renal RI and/or AA. There are limited data about rare mutations on severity of the disease and RI. Today, evaluating genotype–phenotype correlations in rare mutations is important to better understand FMF. We aimed to evaluate clinical, demographic and genetic changes and genotype–phenotype correlations in pediatric patients with FMF over thirty years as well as the importance of the rare mutations. Methods: A total of 2765 pediatric patients with FMF were included in this study. Genetic results were firstly divided into ten groups including rare mutations. Rare mutations were seen in 2% of all patients and divided into eight groups. Results: There was a significant increase in compound heterozygous mutations, E148Q het/hom, R202Q het/hom, complex mutations and rare mutations in the last decade. RI wo AA was 5.8% and AA was 1% in the patients with rare mutations. While M694V and compound het with M694V were positively correlated with severe PRAS, E148Q and V726A were negatively correlated with severe PRAS (p < 0.05, R = 0.137, R = −0.077, R= −0.05, respectively). Although K695R mutation was negatively correlated with severe PRAS (p < 0.05, R = −0.04), the rate of RI was 20%. Although the rare mutation R761H was negatively correlated with severe PRAS (p < 0.05, R = −0.051), the colchicine resistance rate was 8.3%. Conclusions: It may be misleading for clinicians that mutations which have increased in frequency over the years are clinically mild. RI and AA rates in rare mutations are not less than the related rates in common mutations.
Echocardiographic Assessment of Biventricular Mechanics in Patients with Mild-to-Moderate Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis
Authors: Sonaglioni Andrea , Caminati Antonella , Nicolosi Gian Luigi , Muti-Schünemann Giovanna Elsa Ute , Lombardo Michele , Harari Sergio
Published: January 2025

Background: Over the last few years, a few imaging studies have performed conventional transthoracic echocardiography (TTE) implemented with speckle tracking echocardiography (STE) for the assessment of biventricular mechanics in patients with non-advanced idiopathic pulmonary fibrosis (IPF). This systematic review and meta-analysis aimed at evaluating the overall effect of mild-to-moderate IPF on the main indices of biventricular systolic function assessed by TTE and STE. Methods: All imaging studies assessing right ventricular (RV)-global longitudinal strain (GLS), left ventricular (LV)-GLS, tricuspid annular plane systolic excursion (TAPSE), and left ventricular ejection fraction (LVEF) in IPF patients vs. healthy controls, selected from PubMed, Scopus, and EMBASE databases, were included. Continuous data (RV-GLS, LV-GLS, TAPSE, and LVEF) were pooled as standardized mean differences (SMDs) comparing the IPF group with healthy controls. The SMD of RV-GLS was calculated using the random-effect model, whereas the SMDs of LV-GLS, TAPSE, and LVEF were calculated using the fixed-effect model. Results: The full texts of 6 studies with 255 IPF patients and 195 healthy controls were analyzed. Despite preserved TAPSE and LVEF, both RV-GLS and LV-GLS were significantly, although modestly, reduced in the IPF patients vs. the controls. The SMD was large (−1.01, 95% CI −1.47, −0.54, p < 0.001) for RV-GLS, medium (−0.62, 95% CI −0.82, −0.42, p < 0.001) for LV-GLS, small (−0.42, 95% CI −0.61, −0.23, p < 0.001) for TAPSE, and small and not statistically significant (−0.20, 95% CI −0.42, 0.03, p = 0.09) for LVEF assessment. Between-study heterogeneity was high for the studies assessing RV-GLS (I2 = 80.5%), low-to-moderate for those evaluating LV-GLS (I2 = 41.7%), and low for those measuring TAPSE (I2 = 16.4%) and LVEF (I2 = 7.63%). The Egger’s test yielded a p-value of 0.60, 0.11, 0.31, and 0.68 for the RV-GLS, LV-GLS, TAPSE, and LVEF assessment, respectively, indicating no publication bias. On meta-regression analysis, none of the moderators was significantly associated with effect modification for RV-GLS (all p > 0.05). The sensitivity analysis supported the robustness of the results. Conclusions: RV-GLS impairment is an early marker of subclinical myocardial dysfunction in mild-to-moderate IPF. STE should be considered for implementation in clinical practice for early detection of RV dysfunction in IPF patients without advanced lung disease.
A Review of LCA Studies on Marine Alternative Fuels: Fuels, Methodology, Case Studies, and Recommendations
Authors: Wang Yue , Xiao Xiu , Ji Yulong
Published: January 2025

Life Cycle Assessment (LCA) methodology can be used to quantitatively assess the greenhouse gas emissions of low- or zero-carbon marine alternative fuels throughout their life cycle (from well to wake) and is an important basis for ensuring a green energy transition in the shipping industry. This paper first clarifies the trends and requirements of low-carbon development in shipping and introduces the major ship emission reduction technologies and evaluation methods. Next, the characteristics of various alternative marine fuels (i.e., LNG, hydrogen, methanol, ammonia, and biofuels) are comprehensively discussed and analyzed in terms of production, storage, transportation, and ship applications. In addition, this work provides a comprehensive overview of LCA methodology, including its relevant standards and assessment tools, and establishes a framework for LCA of marine alternative fuels. On this basis, a literature review of the current research on LCA of marine alternative fuels from the perspectives of carbon emissions, pollution emissions, and economics is presented. The case review covers 64 alternative-fueled ships and 12 groups of fleets operating in different countries and waters. Finally, this paper discusses the main shortcomings that exist in the current research and provides an outlook on the future development of LCA research of marine alternative fuels.
Multi-Period Operational Modelling and Optimization for Large-Scale Natural Gas Networks Considering Linepack Functions in Long-Distance Transmission Pipelines
Authors: Zhang Wenwen , Tang Qiaoqiao , Gao Xuenong , Zhou Rujin
Published: January 2025

As a promising energy resource, offshore natural gas is primarily used for power generation. The comprehensive offshore gas-to-power system, which includes extraction, treatment, compression, pipeline transmission, and power generation, is extensive and operates within various regulatory, operational, and financial constraints. This complexity offers opportunities to optimize one or more system operations to enhance profitability while fulfilling user demands and environmental considerations. In this research, we present a model-based, computer-aided framework that intuitively connects upstream natural gas operations with downstream power generation and distribution. We develop a multi-period Mixed-Integer Nonlinear Programming (MINLP) model that integrates gas treatment, compression, and long-distance transmission with power generation. The model combines first-principle mechanistic process models with a linepack model that calculates the gas volume storable in long-distance pipelines for transmission. The linepack model facilitates gas storage and withdrawal across different periods to accommodate demand scheduling. We apply this framework using the MINLP model in three scenarios: profit maximization, cost minimization, and supply-demand balancing using linepack. The results demonstrate improved economic performance for offshore natural gas-based power generation in China under varying periodic power demands.
A Field Trial to Study the Effects of Stenella attenuata Deterrent on the Catch of a Light-Falling Net Fishery
Authors: Wang Teng , Li Jie , Yan Lei , Xie Bin , Zhang Peng , Song Zhongchang , Li Min , Fu Weijie , Zhang Yu
Published: January 2025

The incidental capture (bycatch) of protected cetaceans in fishing gear has become a serious problem worldwide. Bycatch has also had many serious consequences for pantropical spotted dolphins (Stenella attenuata) in the light-falling net fishery within this research area. We provided a self-developed acoustic deterrent device and conducted trials to investigate the long-term deterrent effects on Stenella attenuata and assess the influence of external factors on fishing catch. In 2022, 50 deterrence trials were conducted, of which 38 were effective and 12 were ineffective. In 2023, 30 deterrence trials were conducted: 24 effective and 6 ineffective. No dolphin bycatch occurred within a two-year period. Overall, the catch per unit effort (CPUE) of the effective deterrence nights was 4.96 ± 3.06 kg/min, while the CPUE of the ineffective nights was 3.78 ± 3.10 kg/min. There was a significant difference (p = 0.041, >0.05) between the two conditions. On the nights when dolphins did not appear, the average CPUE was 5.04 ± 4.44 kg/min. This CPUE was not different from the night on which deterrence was successful (p = 0.981, >0.05), but was considerably higher than night on which deterrence was unsuccessful (p = 0.028, <0.05). General additive model results indicate that month, longitude, flow direction, latitude, wind direction, dolphin number, and wind speed affect fish catch. The ADD may be improved by manually controlling the pulse frequency, transmission interval, and type to improve deter efficiency.
Carbon Policies and Liner Speed Optimization: Comparisons of Carbon Trading and Carbon Tax Combined with the European Union Emissions Trading Scheme
Authors: Sun Ming , Vortia Midakpe P. , Xiao Guangnian , Yang Jing
Published: January 2025

This paper explores how optimizing vessel speeds can help reduce carbon emissions in the maritime industry. Focusing on liner shipping routes between China and Europe, it examines how carbon pricing mechanisms, including carbon taxes and emissions trading under the European Union Emissions Trading Scheme (EU ETS), impact operational costs and emissions reduction. With the use of advanced optimization methods, such as the Non-dominated Sorting Genetic Algorithm-II (NSGA-II) and the Technique for Order of Preference by Similarity to an Ideal Solution (TOPSIS), this research explores the balance between adjusting vessel speeds and minimizing emissions. The findings show that shipping companies on the China–Europe route can reduce the financial strain of carbon pricing by carefully managing speeds and voyage times. This study compares two scenarios of carbon tax policy and carbon trading rights in terms of voyage costs and carbon emissions. The results of this comparison based on the given parameters indicate a reduction of 1124 tons of carbon emissions with the carbon tax policy scenario, while the carbon trading rights scenario allows for more voyages yearly (5.24 vs. 5.30). This demonstrates one policy being more economical, while the other is also more environmentally efficient. These insights support the development of strategies that align environmental goals with economic priorities, paving the way for more sustainable maritime operations. The study introduces its objectives and reviews relevant literature by presenting a detailed methodology, incorporating emissions modeling with clearly defined parameters. The analysis presents results that undergo sensitivity testing and limitations using MATLAB (R2022a version). The study concludes by discussing policy implications and recommendations for future research and practical advancement
From Traditional Nanoparticles to Cluster-Triggered Emission Polymers for the Generation of Smart Nanotheranostics in Cancer Treatment
Authors: Blasco-Navarro Cristina , Alonso-Moreno Carlos , Bravo Iván
Published: January 2025

Nanotheranostics integrates diagnostic and therapeutic functionalities using nanoscale materials, advancing personalized medicine by enhancing treatment precision and reducing adverse effects. Key materials for nanotheranostics include metallic nanoparticles, quantum dots, carbon dots, lipid nanoparticles and polymer-based nanocarriers, each offering unique benefits alongside specific challenges. Polymer-based nanocarriers, including hybrid and superparamagnetic nanoparticles, improve stability and functionality but are complex to manufacture. Polymeric nanoparticles with aggregation-induced emission (AIE) present promising theranostic potential for cancer detection and treatment. However, challenges such as translating the AIE concept to living systems, addressing toxicity concerns, overcoming deep-tissue imaging limitations, or ensuring biocompatibility remain to be resolved. Recently, cluster-triggered emission (CTE) polymers have emerged as innovative materials in nanotheranostics, offering enhanced fluorescence and biocompatibility. These polymers exhibit increased fluorescence intensity upon aggregation, making them highly sensitive for imaging and therapeutic applications. CTE nanoparticles, crafted from biodegradable polymers, represent a safer alternative to traditional nanotheranostics that rely on embedding conventional fluorophores or metal-based agents. This advancement significantly reduces potential toxicity while enhancing biocompatibility. The intrinsic fluorescence allows real-time monitoring of drug distribution and activity, optimizing therapeutic efficacy. Despite their potential, these systems face challenges such as maintaining stability under physiological conditions and addressing the need for comprehensive safety and efficacy studies to meet clinical and regulatory standards. Nevertheless, their unique properties position CTE nanoparticles as promising candidates for advancing theranostic strategies in personalized medicine, bridging diagnostic and therapeutic functionalities in innovative ways.
Floral Visitors and Florivory in Tacinga inamoena (Cactaceae) in the Ex Situ Collection of the Rio de Janeiro Botanical Garden
Authors: Gonzaga Diego Rafael , Tortorelli Ricardo Maximo , de Almeida Thaís Moreira Hidalgo , Peixoto Ariane Luna
Published: January 2025

Tacinga inamoena (K. Schum.) N.P. Taylor & Stuppy (Cactaceae, Opuntioideae) is a native Brazilian species found in the Caatinga phytogeographic domain. Although its flowers are adapted for bird pollination (ornithophily), few birds visit these plants in the ex situ collection at the Rio de Janeiro Botanical Garden. Despite this, fruit production occurs, prompting an investigation into the floral visitors and other animals interacting with T. inamoena flowers. This study aimed to identify floral visitors and quantify florivory damage to flowers in the Cacti and Succulents thematic collection. During the study, 79 flowers were monitored, along with their floral visitors and 26 instances of florivory, totaling 110 observation hours during the anthesis period. Despite recording only five hummingbird visits, a high fruit set was observed, with 72 fruits formed. Results indicated that bees of the genus Trigona sp. were the main floral visitors. Florivory damage, primarily caused by lizards of the species Tropidurus torquatus (Wied-Neuwied, 1820), did not negatively impact fruit formation in this cactus species under cultivation. To fully understand the reproductive success of this species, further studies are needed to assess the viability of seeds formed under these conditions, as the species may be self-compatible and autogamous.
Multidimensional Visual Preferences and Sustainable Management of Heritage Canal Waterfront Landscape Based on Panoramic Image Interpretation
Authors: Jiang Xin , Li Xin , Wang Mingrui , Zhang Xi , Zhang Wenhai , Li Yongjun , Cong Xin , Zhang Qinghai
Published: January 2025

As an important type of linear cultural heritage and a waterfront landscape that integrates both artificial and natural elements, heritage canals provide the public with a multidimensional perceptual experience encompassing aesthetics, culture, and nature. There remains a lack of refined, micro-level studies on heritage canal landscapes from a multidimensional perspective of visual preference. This study focuses on a typical segment of the Grand Canal in China, specifically the ancient canal section in Yangzhou. We employed SegFormer image semantic segmentation techniques to interpret features from 150 panoramic images, quantitatively identifying the waterfront environmental characteristics of the heritage canal. Four perceptual dimensions were constructed: aesthetic preference, cultural preference, natural preference, and hydrophilic preference. Through a questionnaire survey and various statistical analyses, we revealed the relationships between visual preferences for the waterfront landscape of heritage canals and environmental characteristics. The main findings of the study include the following: (1) Aesthetic preference is positively correlated with cultural, natural, and hydrophilic preferences, while natural preference shows a negative correlation with cultural and hydrophilic preferences. (2) Aesthetic preference is influenced by a combination of blue-green natural elements and artificial factors. Natural preference is primarily affected by increased vegetation visibility, cultural preference is associated with a higher proportion of cultural facilities and high-quality pavements, and hydrophilic preference is linked to larger water surface areas, fewer barriers, and better water quality. (3) There are spatial differences in canal waterfront landscape preferences across different urban areas, with the old city exhibiting higher aesthetic, cultural, and hydrophilic preferences than the new city and suburban areas. Finally, this study proposes strategies for optimising and enhancing the quality of waterfront landscapes of heritage canals, aiming to provide sustainable practical guidance for the future planning and management of these heritage sites.
A Systematic Literature Review of Water-Sensitive Urban Design and Flood Risk Management in Contexts of Strategic Urban Sustainability Planning
Authors: Tasnia Tahia , Growe Anna
Published: January 2025

Despite various sustainable urban development frameworks, over the years, inadequate land use patterns and infrastructure have worsened existing problems related to climate disasters such as flooding, heavy precipitation and droughts. Based on a systematic PRISMA literature search and bibliographic analysis, we analyzed statistical data from 44 articles relevant to water-sensitive urban design (WSUD) and flood risk management (FRM) worldwide from 2013 to 2023. We focused on specific selection criteria that focused on settlement typologies and outcomes, indicators and planning approaches to analyze the impact of flooding on urban infrastructure of four different settlement types in 23 case studies, summarized into nine different approaches. The results show that WSUD and FRM have shared sustainability goals but differ in their focus and applicability depending on the settlement type and indicators. In the context of strategic planning for urban sustainability, it can be stated that WSUD has a much stronger focus on integration and future orientation than FRM. Therefore, WSUD seems better suited to be linked to strategic planning for urban sustainability than FRM. Finally, we propose to extend WSUD to “water-sensitive regional design (WSRD)”. This broader framework would integrate regional hydrological, ecological and socioeconomic aspects to address water issues at a larger scale.
Regional Carbon Storage Dynamics Driven by Tea Plantation Expansion: Insights from Meitan County, China
Authors: Zuo Renhui , Ma Yan , Tang Ming , Luo Hao , Li Junqin , Liao Tao , Gong Yuanfang , Zhang Shunfu , Gong Jiyi , Yi Yin
Published: January 2025

Over the past two decades, the tea plantation area in Meitan County, China, has expanded nearly 30-fold, driving significant land use and cover changes (LUCC) with unclear impacts on regional carbon storage. This study uses the PLUS-InVEST model to analyze LUCC impacts on carbon storage from 2000 to 2020 and predict future changes by 2060. Results show a decline in total carbon storage from 3977.83 × 104 t in 2000 to 3960.85 × 104 t in 2020, primarily due to reductions in cultivated land and grassland. Although carbon storage in forest land and tea plantations increased, the overall trend remained negative. Multi-scenario simulations indicate that the sustainable development scenario (SDS) mitigates carbon loss, with a decrease of 31.53 × 104 t, compared to larger reductions in the natural development (NDS) and economic development (EDS) scenarios. Under the SDS scenario, carbon storage in forest land and grassland increased while construction land expansion was controlled. This study emphasizes optimizing land use and agricultural management to enhance carbon sequestration and protect ecosystems, highlighting the need for a balance between ecological protection and economic development for sustainable carbon management in Meitan County.
CamKIIα and VPAC1 Expressions in the Caudal Trigeminal Nucleus of Rats After Systemic Nitroglycerin Treatment: Interaction with Anandamide
Authors: Nagy-Grócz Gábor , Spekker Eleonóra , Körtési Tamás , Laborc Klaudia Flóra , Bohár Zsuzsanna , Fejes-Szabó Annamária , Vécsei László , Párdutz Árpád
Published: January 2025

Migraines are a frequently occurring neurological condition that affects up to 16% of the global population. The precise pathomechanism of the disease remains unknown, but from animal and human observations, it appears that calcium/calmodulin-dependent protein kinase II alpha (CamKIIα), pituitary adenylate cyclase-activating polypeptide (PACAP), and vasoactive intestinal polypeptide (VIP) are involved in its pathogenesis. One of the animal models of migraines uses the systemic administration of nitroglycerin (NTG), which, as a nitric oxide (NO) donor, initiates a self-amplifying process in the trigeminal system, leading to central sensitization. Endocannabinoids, such as anandamide (AEA), are thought to play a modulatory role in trigeminal activation and sensitization phenomena. In the present experiment, we aimed to investigate the effect of NTG and AEA on CamKIIα, PACAP/VIP, and vasoactive intestinal polypeptide type 1 receptor (VPAC1) expression levels in the upper cervical spinal cord (C1-C2) of rats, where trigeminal nociceptive afferents are clustered. Four groups of animals were formed: in the first group, the rats received only the vehicle; in the second group, they were treated with an intraperitoneal injection of NTG (10 mg/kg); animals in the third and fourth groups received AEA (2 × 5 mg/kg) half an hour before and one hour after the placebo or treatment with NTG. Four hours after the placebo/NTG injection, the animals were transcardially perfused, and the cervical spinal cords were removed for Western blot. Our results show that both NTG and AEA alone can increase the expression of CamKIIα and VPAC1 in the C1-C2 segments. Interestingly, the combination of NTG and AEA had no such effect on these markers, possibly due to various negative feedback mechanisms.
CFD-Based Investigation of Static and Dynamic Pressure Effect in Aerostatic Bearings with Annular Grooves at High Speed
Authors: Song Wentao , Li Minggui , Cheng Peng , Wang Decheng , Shao Chenxi , Zhou Junying
Published: January 2025

Based on the SST k-ω turbulence model, this study investigated the flow fields of annular groove and non-groove small-hole throttling aerostatic bearings (AGSTABs and STABs). It examined the formation mechanisms of static and dynamic pressure effects in both flow fields at high speed, evaluating how parameters such as eccentricity, groove width ratio, and depth ratio influence the average load capacity and static and dynamic pressure effects. The findings show that STABs combine static and dynamic pressure effects at high speeds, while AGSTABs decouple them to enhance load capacity, simultaneously reducing vortex and backflow intensity. At low eccentricities, AGSTABs exhibit superior performance over STABs, achieving 20% higher average load capacity at 0.1 eccentricity. Additionally, increasing eccentricity enhances static and dynamic pressure effects in both bearings. A larger groove width ratio decreases the throttling efficiency and dynamic pressure, with pressure dropping from 3.5 MPa (static) to 1.6 MPa, and 6.3 MPa (dynamic) to 1.7 MPa respectively, at 30,000 RPM. In contrast, the depth ratio of annular groove has only a minor impact on static and dynamic pressure effects.
(E)-3-Mesityl-1-(2,3,5,6-tetramethylphenyl)prop-2-en-1-one
Authors: McKay Aidan P. , Cordes David B. , Smellie Iain A. , Chalmers Brian A.
Published: January 2025

We report the synthesis and characterisation of the previously unknown (E)-3-Mesityl-1-(2,3,5,6-tetramethylphenyl)prop-2-en-1-one by NMR spectroscopy, IR spectroscopy, melting point, mass spectrometry, and X-ray crystallography.
Influence of Compaction Methods on Properties of Roller-Compacted Concrete Pavement Wearing Surfaces
Authors: Stępień Justyna , Chomicz-Kowalska Anna , Tutaj-Dudała Magdalena , Dudała Michał , Maciejewski Krzysztof , Ramiączek Piotr , Iwański Mateusz Marek
Published: January 2025

The present study investigates the effects of different compaction methods on the properties of roller-compacted concrete (RCC) used for road pavements. The study focuses on comparing the Proctor compaction method utilizing different compaction efforts and molds (2.5 kg rammer with three layers of 56 blows and 4.5 kg with three and five layers of 56 blows, cylindrical and cube molds) with a slab compactor in static and vibratory setting. The samples produced in a slab compactor were obtained by drilling from the prepared slab. The evaluated properties of the samples included compressive strength and bulk density. The study involved a C25/30 concrete with the intention to be used in low volume roads according to national standards. The study concluded that the utilization of Proctor compaction and slab compactor with vibratory setting provided similar levels of strength performance of the RCC mixture, regardless of the shape of the Proctor compacted samples. In terms of the bulk densities, the main differentiating factor in the case of Proctor compaction was the weight of the rammer. The compressive strength of the samples was also strongly related to their bulk densities.
Effects of Hypergravity on Phase Evolution, Synthesis, Structures, and Properties of Materials: A Review
Authors: Zheng Yisheng , Xie Lilin , Chen Yanhui , Han Xiaodong
Published: January 2025

In a hypergravity environment, the complex stress conditions and the change in gravity field intensity will significantly affect the interaction force inside solid- and liquid-phase materials. In particular, the driving force for the relative motion of the phase material, the interphase contact interaction, and the stress gradient are enhanced, which creates a nonlinear effect on the movement mode of the phase material, resulting in a change in the material’s behavior. These changes include increased stress and contact interactions; accelerated phase separation; changes in stress distribution; shear force and phase interface renewal; enhanced interphase mass transfer and molecular mixing; and increased volume mass transfer and heat transfer coefficients. These phenomena have significant effects on the synthesis, structural evolution, and properties of materials in different phases. In this paper, the basic concepts of hypergravity and the general rules of the effects of hypergravity on the synthesis, microstructure evolution, and properties of materials are reviewed. Based on the development of hypergravity equipment and characterization methods, this review is expected to broaden the theoretical framework of material synthesis and mechanical property control under hypergravity. It provides theoretical reference for the development of high-performance materials under extreme conditions, as well as new insights and methods for research and application in related fields.