bluuebunny/crossref_metadata_2025 huggingface dataset:
The HOME FAST BRAZIL self-report version: translation and transcultural adaptation into Brazilian Portuguese
Authors: Melo Filho Jarbas , Bazanella Natacha Verônica , Vojciechowski Audrin Said , Costa Elisiê Rossi Ribeiro , Mackenzie Lynette , Gomes Anna Raquel Silveira
Published: May 2020

Objective

To translate and cross-culturally adapt the Home Falls and Accidents Screening Tool Self-report into Brazilian Portuguese and to correlate with the history of falls.

Methods

The translation and transcultural adaptation process followed international parameters. The Home Falls and Accidents Screening Tool Brazil Self-report, the Mini-Mental State Examination and the history of falls were applied to 10 elderly in the pre-test and to 41 in the final. Demographic and anthropometric data were also evaluated. Spearman correlation coefficient was performed.

Results

The participants considered the questionnaire easy to understand and did not report any doubts to answer the final version. There was significant correlation between: Home Falls and Accidents Screening Tool Brazil Self-report score and number of falls (ρ = 0.31, p = 0.02) and the lighting and bathroom domains with presence of falls at home (ρ = 0.44, p = 0.00 and ρ = 0.33, p = 0.02, respectively). The questionnaire indicated fall’s risk scoring, 10(±2).

Conclusion

The Home Falls and Accidents Screening Tool Brazil Self-report showed to be comprehensible and feasible tool for self-assessment of domiciliary falls risk in Brazilian older people. The scores indicated fall’s risk and were associated with the history of falls.
Risk factors of uncontrolled periprosthetic knee joint infection after two-stage reimplantation
Authors: Kim Du-Han , Bae Ki-Cheor , Kim Dong-Wan , Choi Byung-Chan
Published: May 2020

Background

Periprosthetic infection after total knee arthroplasty is a challenging problem, and physicians should identify risk factors to decrease recurrence. However, risk factors for reinfection with two-stage reimplantation have not yet been well established. The purpose of this study was to assess treatment outcomes of subsequent two-stage knee reimplantation and identify risk factors for uncontrolled periprosthetic knee joint infections.

Methods

We retrospectively reviewed 70 knees diagnosed with a periprosthetic knee joint infection treated with two-stage reimplantation between September 2011 and October 2016 at our institution. Patients in the controlled infection group (group C) required no further medication or surgical treatment within 2 years after reimplantation. Patients in the uncontrolled infection group (group U) displayed symptoms of active infection after resection arthroplasty or were reinfected after two-stage reimplantation. We compared group C and group U, and analyzed potential risk factors for uncontrolled prosthetic joint infection (PJI).

Results

Of 70 knees included in this analysis, 53 (75.7%) were clinically deemed free from infection at the latest follow-up. The remaining 17 knees (24.3%) required additional surgical procedures after two-stage reimplantation. Demographics were not statistically significantly different between the two groups. Wound complications were statistically more frequent in group U (p = 0.030). Pre-reimplantation C-reactive protein (CRP) was statistically different between groups C and U (0.44 and 1.70, respectively, p = 0.025). Among the cultured microorganisms, fungus species were statistically more frequently detected in group U compared with group C (p = 0.031).

Conclusions

The reinfection rate of our two-stage reimplantation protocol was 24.3% in the included cases. Wound complications, higher pre-reimplantation CRP levels, and fungus species were statistically more common in group U compared with group C. Our findings will help in counseling patients and physicians to understand that additional caution may be required when treating PJI if the aforementioned risk factors are present.

Level of evidence

IV, case series.
Demystifying neuroscience laboratory techniques used to investigate single-gene disorders
Authors: Mizen Lindsay A. M. , Stanfield Andrew C.
Published: May 2020

There is considerable work being carried out in neuroscientific laboratories to delineate the mechanisms underlying single-gene disorders, particularly those related to intellectual disability and autism spectrum disorder. Many clinicians will have little if any direct experience of this type of work and so find the procedures and terminology difficult to understand. This article describes some of the laboratory techniques used and their increasing relevance to clinical practice. It is pitched for clinicians with little or no laboratory science background.
Toward a Common Goal: Improving Safety of Oral Chemotherapy Prescribing Practices at a Jurisdictional Level
Authors: Campbell Marla , Vu Kathy , Pardhan Aliya , Gallo-Hershberg Daniela , Ku Rosemary , Redwood Erin , Simanovski Vicky , Krzyzanowska Monika K.
Published: May 2020

PURPOSE:

Extending the safety agenda from parenteral to oral chemotherapy was identified as a provincial improvement priority in the 2014-2019 Cancer Care Ontario (CCO) Systemic Treatment Provincial Plan. Elimination of handwritten prescriptions for oral chemotherapy was one of the specific goals and led to a provincial quality improvement (QI) initiative involving systemic treatment facilities across 14 regional cancer programs.

METHODS:

The initiative was centrally organized by CCO but locally implemented by the regional partners. CCO provided templates and tools, such as preprinted orders (PPOs), project charters, and an evaluation plan, and facilitated cross-jurisdictional knowledge sharing and exchange. Regions had flexibility in determining their local implementation strategies and were responsible for conducting chart audits to evaluate implementation success. Each participating hospital completed 3 audits—at baseline, immediately after implementation (audit 1), and 1 year later (audit 2)—using either a clinic-based or an outpatient pharmacy–based assessment.

RESULTS:

Thirty-five facilities providing systemic treatment participated. At baseline, the provincial average for the use of computerized physician order entry (CPOE) or PPOs for prescribing oral chemotherapy was 71%. After implementation of the QI initiative, the provincial average for the use of CPOE or PPO increased to 91% at audit 1 and 95% at audit 2.

CONCLUSION:

Although not all facilities met the goal of 100% CPOE or PPO compliance, the QI initiative led to improvement in safe prescribing practices for oral chemotherapy. A coordinated QI approach between a central decision maker and local partners can be an effective strategy to encourage high-quality cancer care and promote a culture of safety across a jurisdiction.
Multiple Limb Involvement in a Severe Case of Complex Regional Pain Syndrome Treated With Spinal Cord Stimulation: A Case Report
Authors: Eriksen Linda E. , Terkelsen Astrid J. , Sørensen Jens Christian H. , Knudsen Anne Lene H. , Meier Kaare
Published: May 2020

Complex regional pain syndrome (CRPS) can be a debilitating, persistent, and treatment-resistant pain condition. This report presents a case of severe CRPS affecting multiple limbs, resistant to standard treatment modalities. Treatment with spinal cord stimulation (SCS) had an initial good effect. Nevertheless, the CRPS continued to progress, eventually affecting all 4 extremities. A lead fracture resulted in a rapidly developing recurrence of CRPS in the patient’s arm, necessitating amputation. SCS may be an effective modality for treatment of severe CRPS. However, mechanical problems should always be considered when an SCS-implanted patient experiences rapid symptom progression or abrupt cessation of stimulation.
Determinants of the implied equity risk premium in Brazil
Authors: Sanvicente Antonio Zoratto , Carvalho Mauricio Rocha
Published: May 2020

This paper proposes and tests market determinants of the equity risk premium (ERP) in Brazil. We use implied ERP, based on the Elton (1999) critique. We demonstrate that the calculation of implied, as opposed to historical ERP makes sense, because it varies, in the expected direction, with changes in fundamental market indicators. The ERP for Brazil is calculated as a mean of large samples of individual stock prices in each month in the January, 1995 to September, 2015 period, using the “implied risk premium” approach. As determinants of changes in the ERP we obtain, as significant, and in the expected direction: changes in CDI rate, country debt risk spread, US market liquidity premium and level of the S&P500. The influence of the proposed determining factors is tested with the use of time series regression analysis. The possibility of a change in that relationship with the 2008 crisis was also tested, and the results indicate that the global financial crisis had no significant impact on the nature of the relationship between the ERP and its determining factors. For comparison purposes, we also consider the same variables as determinants of the ERP calculated with average historical returns, as is common in professional practice. First, the constructed series does not exhibit any relationship to known market events. Second, the variables found to be significantly associated with historical ERP do not exhibit any intuitive relationship with compensation for market risk.
Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes
Authors: Brunker Kirstyn , Jaswant Gurdeep , Thumbi S.M. , Lushasi Kennedy , Lugelo Ahmed , Czupryna Anna M. , Ade Fred , Wambura Gati , Chuchu Veronicah , Steenson Rachel , Ngeleja Chanasa , Bautista Criselda , Manalo Daria L. , Gomez Ma. Ricci R. , Chu Maria Yna Joyce V. , Miranda Mary Elizabeth , Kamat Maya , Rysava Kristyna , Espineda Jason , Silo Eva Angelica V. , Aringo Ariane Mae , Bernales Rona P. , Adonay Florencio F. , Tildesley Michael J. , Marston Denise A. , Jennings Daisy L. , Fooks Anthony R. , Zhu Wenlong , Meredith Luke W. , Hill Sarah C. , Poplawski Radoslaw , Gifford Robert J. , Singer Joshua B. , Maturi Mathew , Mwatondo Athman , Biek Roman , Hampson Katie
Published: May 2020

Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely to monitor endemic disease transmission and control in low- and middle-income countries. Rabies is an almost invariably fatal viral disease that causes a large public health and economic burden in Asia and Africa, despite being entirely vaccine preventable. With policy efforts now directed towards achieving a global goal of zero dog-mediated human rabies deaths by 2030, establishing effective surveillance tools is critical. Genomic data can provide important and unique insights into rabies spread and persistence that can direct control efforts. However, capacity for genomic research in low- and middle-income countries is held back by limited laboratory infrastructure, cost, supply chains and other logistical challenges. Here we present and validate an end-to-end workflow to facilitate affordable whole genome sequencing for rabies surveillance utilising nanopore technology. We used this workflow in Kenya, Tanzania and the Philippines to generate rabies virus genomes in two to three days, reducing costs to approximately £60 per genome. This is over half the cost of metagenomic sequencing previously conducted for Tanzanian samples, which involved exporting samples to the UK and a three- to six-month lag time. Ongoing optimization of workflows are likely to reduce these costs further. We also present tools to support routine whole genome sequencing and interpretation for genomic surveillance. Moreover, combined with training workshops to empower scientists in-country, we show that local sequencing capacity can be readily established and sustainable, negating the common misperception that cutting-edge genomic research can only be conducted in high resource laboratories. More generally, we argue that the capacity to harness genomic data is a game-changer for endemic disease surveillance and should precipitate a new wave of researchers from low- and middle-income countries.
Algorithmization of Project Management Processes
Authors: Tsiteladze David
Published: May 2020

The paper analyzes the systematic approach of project management. The description of the structural elements of a systematic approach is given — the project management methodology, game theory and system thinking theory. Due to the qualitative differences between the projects, the levels of project structuring and the needs of interested parties, the work describes a seriesparallel nature of the development stages of the project management. The paper proposes an algorithm for the basic project management processes that is fair for each functional area of the project. Using this algorithm will allow the project manager to increase the quality of management decisions and significantly reduce efforts and time for organizing the project management process.
Project and Program Management of the Regional Sustainable Development: Features and Theoretical Approaches Review
Authors: Kurganov Maksim
Published: May 2020

The growing importance of regions as subjects of economic relations and part of a single economic space naturally leads to the need to improve methods and tools for managing regional development. At the same time, at the present stage of economic development, one of the key forms of socio-economic changes is a project activity that defines the principles and characteristics of managerial functions. In the modern world, special attention is paid to achieving sustainable socio-economic development of the region. Due to the fact that modern society solves the problems associated with the continuous assessment of the feasibility of costs for achieving economic results and ensuring stable economic growth, environmental problems and maintaining a balanced development of social and economic spheres remain key problems in the context of regional development. The relevance of this article can be defined as an attempt to systematize existing paradigms and approaches to organizing the management of programs and projects for the regional development within the perspective of the of sustainable development concept, as well as considering related issues considered in scientific works and modern management practice. The main aim of the work is to review the existing theoretical and methodological approaches to the management of programs and projects for sustainable regional development and to identify the features of project management of this type.
O (nie)widoczności prowadzącego spotkanie ze świadkiem historii – wstępna typologia ról inicjujących wywiady narracyjne
Authors: Duda Beata , Sujkowska-Sobisz Katarzyna , Ciesek-Ślizowska Bernadetta
Published: May 2020

ON THE (IN)VISIBILITY OF THE LEADER IN A MEETING WITH A WITNESS OF HISTORY: A PRELIMINARY TYPOLOGY OF ROLES THAT INITIATE NARRATIVE INTERVIEWS

The paper reflects on sender-recipient relations characteristic for the participants of a narrative interview with a witness of history. The research material comprises 1931 verbal activities, collected in the Archive of Oral History of The Warsaw Rising Museum, of people who conducted 32 meetings with participants of the Warsaw Uprising in 1944. The application of the interactive concept of text allowed us to create a preliminary typology of the activities of meeting leaders, viz. to identify four types of initiation: the opening, the complementary, the deepening and ordering, and the reactive one. Further analyses led to the identification of roles taken on by people who conduct meetings with witnesses of history, which we named the journalist, the researcher, and the friend.
Problemy opisu staropolskiej derywacji czasownikowej
Authors: Janowska Aleksandra
Published: May 2020

PROBLEMS IN THE DESCRIPTION OF OLD POLISH VERBAL DERIVATION

The article discusses the problems associated with the description of verbal derivation in the earliest period of the Polish language. The type of linguistic material that was preserved, the slight amount of attestations, the lack of clarity of the context, are all responsible for the appearance of difficulties associated with the word-formative description of verbs already at the level of the separation of linguistic facts, the establishment of the formant that we are dealing with. Even greater problems are associated with the establishment of the semantic value of derivatives, and with the indication of motivation relations. The author considers the extent to which the methodology that was developed upon contemporary material may be used in research of this kind. She also points out the scholarly ‘neglected’ areas of verbal word-formation of this period.
Identyfikacja tematów na *-(j)ū w materiale polskim i słowiańskim
Authors: Janczulewicz Paweł
Published: May 2020

IDENTIFICATION OF *-(j)ū-STEMS IN POLISH AND SLAVIC MATERIAL

The paper discusses the question of the substitution of the stem suffix *-ъv- for the suffix *-ъka, which converts words from the *-(j)ū- to the *-a-declension, as well as the problem of identification of original *-(j)ū-stems. An analysis of Polish and Slavic material leads to the conclusion that a part of nouns that are commonly regarded as *-(j)ū-stems have in fact a different origin: some can be derived from collective nouns in *-va (still productive in East Slavic), e.g. *kuropъtva, *plotva, *ǫtva, and a part have probably been extended with an unmotivated labial element -v- which has the appearance of a relic of a *-ū-stem, but appears most commonly after roots that end in a velar consonant or a spirant-stop sequence. The paper argues against the hypothesis about late (Proto-)Slavic activization of *-ū-stems and proposes instead that a part of this class had been eliminated at a prehistoric stage, depending on the quality of the stem consonant.
A educação na orientação de pais de bebês e crianças surdas
Authors: Garrutti-Lourenço Erica Aparecida , Campos Sandra Regina Leite de , Holanda Jéssica De Oliveira
Published: May 2020

Este estudo apresenta um relato sobre o percurso de uma família, cujo filho é surdo e recém-implantado. Com dois anos de idade, a criança foi matriculada em uma instituição de Educação Infantil da rede particular e teve o suporte de uma acompanhante terapêutica (AT), além de suas professoras. Como fonte de dados, foram utilizados os registros do diário de campo da AT, que reúnem observações e estratégias feitas na escola, conversas dos interlocutores da criança e uma entrevista com a mãe. Os relatos foram analisados na perspectiva dos estudos de Vygotsky, ressaltando o papel do mediador no desenvolvimento do sujeito, e considerando o seu entorno interacional, fundamental na construção de saberes. Este estudo revela como a família avançou, de um início marcado pela negação da condição do filho na escola, para a busca de alternativas que normatizassem, restabelecessem a fala da criança e que, finalmente, fizessem os pais o reconhecerem como surdo.
Celebrando a normatização da vida: (re)pensando os corpos infantis arbitrariamente generificados em vídeos de “Chás de Revelação” do YouTube
Authors: Couto Junior Dilton Ribeiro , Amaro Ivan , Romeritto Renato , Ruani Ruann Moutinho
Published: May 2020

Fruto de pesquisa de pós-doutorado em educação em andamento, o texto é focado em refletir sobre o enquadramento dos corpos infantis em categorias estáticas, hierarquizantes e binárias expressos em vídeos de “chás de revelação” publicizados no YouTube. Para isso, operamos de forma teórica e metodológica através da abordagem cartográfica e adotamos o YouTube como lócus de pesquisa, rede social que já se constitui como parte do cenário sócio-técnico contemporâneo. As narrativas presentes nos “chás de revelação” trouxeram alguns apontamentos reflexivos preliminares, incluindo a necessidade de problematizarmos as tradições culturais que reforçam a compreensão estereotipada do gênero desde os primeiros anos da criança.
UMA PERSPECTIVA PARA ACOMPANHAR O PROCESSO DOS BEBÊS DE CONQUISTA DA AUTONOMIA NA CRECHE
Authors: Coutinho Angela Scalabrin , Vieira Daniele Marques
Published: May 2020

Este artigo tem por objetivo apresentar elementos para a compreensão da autonomia dos bebês no contexto educativo da creche. Seleciona sequências narrativas que envolvem de modo destacado um bebê e que representam aspectos de seu processo de conquista da movimentação que permitem refletir acerca da autonomia, do movimento e das relações com outros sujeitos, e sua inter-relação no processo de desenvolvimento. A partir da análise das sequências narrativas, destaca que a proposição por parte dos adultos de um entorno óptimo é condição para a conquista da autonomia dos bebês, contudo a ação dos bebês deve ser sempre tomada como referência e compreendida como singular.
INFÂNCIA CRÔNICA
Authors: Figueiredo Amanda Pontes , De Almeida Fernanda , De Lucena Flávia Fernanda Ferreira
Published: May 2020

O livro “Infância Crônica”, organizado por Raíza Venas e Rita Ribes, publicado pela Editora NAU no ano de 2019, reúne uma coletânea de 35 crônicas escritas por pesquisadores que compõem o Grupo de Pesquisa Infância e Cultura Contemporânea, no projeto “Fisionomias da infância: experiências cotidianas, alteridades e deslocamentos”, desenvolvido na Faculdade de Educação da Universidade Estadual do Rio de Janeiro - UERJ. Os pesquisadores têm como foco as relações entre criança e cultura, elegendo como fonte de “inspiração” acontecimentos do mundo contemporâneo para a escrita das crônicas, que retratam as crianças e suas relações com a cidade.
Non-Uniform Magnetic Field Effects on Ferrofluids Film Boiling: A Numerical Study
Authors: Maroofiazar Rasool , Haghgoo Seyyede Fatemeh
Published: May 2020

In this paper the effect of magnetic field on film boiling of ferrofluids on a horizontal flat plate has been investigated. The obtained results indicate that adding nanoparticles into the base fluid changes vapor film characteristics mainly due to changes in thermophysical properties of the base fluid. Also, ferrofluids enhances film boiling heat transfer on horizontal plate specially at higher volume concentration of nanoparticles. Another important result of this study is the effect of non-uniform magnetic field on horizontal film boiling characteristics. Application of magnetic field changes vapor film behavior mostly at higher values of magnetic field intensity (400) and nanoparticles volume fraction (4 percent).
COVID-19: implications for paediatric dental general anaesthetic services
Authors: Zaitoun Halla , Kandiah Pathanjali , Yesudian Grainne , Rodd Helen
Published: May 2020

Will the coronavirus pandemic bring about change in how we manage children with caries?
Late-Photons Hyperspectral Near-Infrared Spectroscopy Improves the Sensitivity to Cerebral Oxygenation in Adults
Authors: Cohen David Jonathan Fulop , Diop Mamadou
Published: May 2020

Monte-Carlo experiments were conducted to investigate the sensitivity of late-photons hyperspectral near-infrared spectroscopy (Lp-hNIRS) for assessing cerebral oxygenation (ScO2) in adults. Results suggest that Lp-hNIRS provides more accurate estimates of ScO2 than multispectral time-resolved NIRS.
Non-invasive estimation of intracranial pressure by diffuse correlation spectroscopy
Authors: Fischer Jonas B. , Ghouse Ameer , Tagliabue Susanna , Maruccia Federica , Rey-Perez Anna , Báguena Marcelino , Cano Paola , Zucca Riccardo , Weigel Udo M. , Sahuquillo Juan , Poca Maria A. , Durduran Turgut
Published: May 2020

We present a proof-of-principle of a method for non-invasive estimation of intracranial pressure in infants and adults based on the pulsatile cerebral blood flow measured by diffuse correlation spectroscopy and employing a recurrent neural network.
Regional heterogeneity of cerebral hemodynamics in neonatal hypoxic-ischemic encephalopathy
Authors: Tian Fenghua , Sepulveda Pollieanna , Liu Yulun , Das Yudhajit , Liu Hanli , Zhang Rong , Chalak Lina
Published: May 2020

Current practice of neuromonitoring in hypoxic ischemic encephalopathy (HIE) is to apply a frontal probe. In this study we determined the regional heterogeneity in cerebral hemodynamics at four regions with multichannel near-infrared spectroscopy.
High-speed compressive line-scanned two photon microscopy
Authors: Alemohammad Milad , Shin Jaewook , Stroud Jasper R. , Foster Mark A.
Published: May 2020

We demonstrate a high-speed, single-pixel, line-scanned temporally focused microscope for wide-field multi-photon imaging in scattering medium such as the brain. By combining patterned illumination and compressive reconstruction we image fluorescent bead samples at up to 500 fps over a 150×100 µm2 imaging FOV.
Comparing wide field to 3D light field for imaging red calcium transients in mammalian brain
Authors: Howe Carmel L. , Quicke Peter , Song Pingfan , Jadan Herman Verinaz , Dragotti Pier Luigi , Foust Amanda J.
Published: May 2020

We apply light field (LF) microscopy to single-cell and bulk-loaded imaging of the red calcium dye, CaSiR-1 in mouse brain slices. We characterize the signal-to-noise ratio of images reconstructed from LF to wide-field time series.
Extended Field-of-View Deep Brain Imaging using Aberration Correction in GRIN Microendoscopes through 3D Printed Polymer Microlenses
Authors: Sattin Andrea , Antonini Andrea , Bovetti Serena , Moretti Claudio , Forli Angelo , Succol Francesca , Rajamanickam Vijayakumar P. , Bertoncini Andrea , Liberale Carlo , Fellin Tommaso
Published: May 2020

We report the development and application of a new approach to correct aberrations in GRIN microendoscopes using 3D printed polymer microlenses. Corrected microendoscopes are validated performing functional imaging experiments in the mouse brain in vivo.
Making Oblique Light-sheet Platform Open
Authors: Kumar Manish , Kozorovitskiy Yevgenia
Published: May 2020

We present an open platform to design, build and operate single objective based oblique light-sheet microscope. Using this platform, here we design and build a new and compact configuration of the microscope.
Deep Learning-based Virtual Refocusing of Fluorescence Microscopy Images for Neuron Imaging in 3D
Authors: Wu Yichen , Rivenson Yair , Wang Hongda , Luo Yilin , Ben-David Eyal , Bentolila Laurent A. , Pritz Christian , Ozcan Aydogan
Published: May 2020

We demonstrate a deep neural network-based virtual refocusing method for fluorescence microscopy, which enables accurate tracking of C. elegans neuron structure and activity in 3D using an image acquired at a single focal plane.
High-Sensitivity Phase Microscopy for Neural Activity
Authors: Lyzwa Dominika , Singh Vijay , Yaqoob Zahid , So Peter T.C.
Published: May 2020

Phase measurement sensitivity of 10−5 is necessary for action potential detection. Current interferometric systems are limited to 10−3 phase sensitivity. Here, we present a method to improve the phase sensitivity.
Super-PON: an evolution for access networks [Invited]
Authors: DeSanti Claudio , Du Liang , Guarin Jhon , Bone Jason , Lam Cedric F.
Published: May 2020

Passive optical networks (PONs) have been widely used in access
networks and are today the access technology of choice for operators,
especially when they need to build new infrastructure. Significant
effort has been put in place across the years to scale the speed of
passive optical networks. The super-PON concept has also been proposed
in order to scale reach and customer aggregation of PONs. However, it
did not produce any standardization efforts nor significant commercial
deployments. In November 2018, the IEEE 802.3 Working Group formed the
P802.3cs “Super-PON” Task Force to standardize a flavor of super-PON
able to support an increased optical reach of up to 50 km and an
expanded customer coverage of up to 1024 customers per fiber over a
passive optical distribution network. A project with near identical
objectives was later started in ITU-T Q2/SG15. This paper presents the
latest updates from these industry standardization efforts, with
special attention to the activity of the IEEE P802.3cs Task Force, and
the technical reasoning behind some of the key decisions that have
been made.
Multi-Resolution Open-Top Light Sheet Microscopy Enabled by a Solid Immersion Meniscus Lens (SIMlens)
Authors: Barner Lindsey A. , Glaser Adam K. , Liu Jonathan T.C.
Published: May 2020

We report the development of a solid immersion meniscus lens (SIMlens), a wavefront-matching optical element for open-top light sheet microscopy that increases numerical aperture and enables multi-resolution imaging with air objectives.
High-speed 3D observation with multi-color light field microscopy
Authors: Lu Zhi , Zhang Yi , Zhu Tianyi , Yan Tao , Wu Jiamin , Dai Qionghai
Published: May 2020

We develop a multi-color light field microscopy to capture high-speed three-dimensional biological dynamics with multiple fluorescence channels. Experiments on zebrafish are demonstrated to visualize high-speed membrane dynamics and blood flows in 3D during heart beating.
A 20 MHz, sub ps, Tunable Ti:sapphire Laser System for Real Time, Stain Free, High Contrast Histology of the Skin
Authors: Fésűs Luca , Krolopp Ádám , Molnár Gábor , Kiss Norbert , Tamás Gábor , Szipőcs Róbert
Published: May 2020

A 20 MHz repetition rate, sub ps Ti:sapphire (Ti:S) laser system is proposed for real time, high chemical contrast dual vibration resonance frequency (DVRF) CARS imaging of the skin suitable for in vivo histology.
Optical aspects of a miniature fluorescence microscope for super-sensitive biomedical detection
Authors: Nie Yunfeng , Sanna Aikio , Kokkonen Annukka , Sipola Teemu , Sanna Uusitalo , Grilli Simonetta , Ottevaere Heidi
Published: May 2020

Current commercial fluorescence microscopes are typically sophisticated, bulky and expensive, not suitable for low-volume and/or clinic routine biomedical detection, e.g. lab-on-chip devices. We present optical design strategies and the principle demonstrator of a miniature fluorescence microscope aiming for super-sensitive detection.
Tracking The Fate of Disseminated Cancer Cells with Surgical Engineering, Intravital Imaging, and Correlative Microscopy
Authors: Entenberg David
Published: May 2020

We use Surgical Engineering to overcome technical challenges to intravital imaging, improving its ability to perform mechanistic, hypothesis-driven investigations of live tissues and making surprising discoveries about how cancer cells spread.
Predicting immunofluorescence images from reflectance microscopy via deep learning
Authors: Cheng Shiyi , Fu Sipei , Kim Yumi Mun , Yi Ji , Tian Lei
Published: May 2020

To circumvent the limitations of immunofluorescence microscopy, we propose a deep learning approach for characterizing morphological information contained in reflectance microscopy with high specificity and enable digital multiplexing.
Imaging Heterogeneity of NAD(P)H in Individual Extracellular Vesicles Using Fluorescence Lifetime Imaging Microscopy (FLIM)
Authors: Sorrells Janet E. , Martin Elisabeth M. , Mukherjee Prabuddha , Aksamitiene Edita , You Sixian , Alex Aneesh , Marjanovic Marina , Boppart Stephen A.
Published: May 2020

Individual extracellular vesicles from human epithelial breast cancer cells were imaged using a custom two-photon fluorescence lifetime imaging microscopy system to assess and characterize the heterogeneity of their NAD(P)H content.
Detection of the DEJ and Segmentation of Its Morphological Patterns in RCM Images of Melanocytic Skin Lesions
Authors: Kose Kivanc , Bozkurt Alican , Fox Christi A. , Gill Melissa , Brooks Dana , Dy Jennifer , Rajadhyaksha Milind
Published: May 2020

Reflectance confocal microscopy (RCM) provides a real-time noninvasive (in-vivo) proxy for histology. Here, we present machine learning models to delineate skin layers in RCM image stacks and analyze morphological patterns in RCM mosaics of skin.
Optical computation for complex OCT
Authors: Wang Yahui , Liu Xuan
Published: May 2020

We describe an innovative optical computation technology that performs Fourier transform optically for complex optical coherence tomography (OCT) imaging. We demonstrated amplitude and phase imaging experimentally using OCT data generated by optical computation.
Quantifying Tissue Mechanical Properties using Optical Coherence Elastography and Brillouin Spectroscopy
Authors: Ambekar Yogeshwari , Raghunathan Raksha , Zhang Jitao , Scarcelli Giuliano , Larin Kirill V.
Published: May 2020

The alteration of biomechanical properties of many tissues could indicate onset and progression of diseases. In this paper we combine dynamic optical coherence elastography with 3D Brillouin Spectroscopy for truly quantitative elastography of ocular tissues.
DFFOCT As a Tool to Detect Cellular Activity
Authors: Gorti Viswanath , Malpani Ravi , Blick Emily , Khare Siddharth , Khaksari Kosar , Scholler Jules , Benoit Emilie , Boccara Claude , Sackett Dan , Gandjbakhche Amir
Published: May 2020

DFFOCT allows for the visualization and characterization of cellular dynamics, providing future direction for cell-targeted therapeutics. In this work, we analyze the potential of DFFOCT to increase understanding of dynamic cellular processes under varying conditions.
De-speckling of Optical Coherence Tomography Images Using a Generative Adversarial Network
Authors: Dong Zhao , Ni Guangming , Liu Guoyan , Jerwick Jason , Zhou Chao
Published: May 2020

We developed a custom generative adversarial network (GAN) that can effectively reduce speckle noise in OCT images and videos without increase system complexity while maintaining spatial and temporal resolutions.
Adaptive spectroscopic visible-light optical coherence tomography for robust clinical retinal oximetry
Authors: Rubinoff Ian , Kuranov Roman , Yang Huili , Beckmann Lisa , Wang Yuanbo , Fawzi Amani , Ghassabi Zeinab , Wollstein Gadi , Ishikawa Hiroshi , Schuman Joel S. , Zhang Hao F.
Published: May 2020

Variable eye motions and refractions challenge the stability of clinical retinal oximetry. We developed adaptive spectroscopic techniques for visible-light optical coherence tomography to achieve highly stable measurements of oxygen concentration in human retinal blood vessels.
Polymer hybrid white quantum dots light-emitting diodes with a nanostructured electron injection layer
Authors: Lee Hsin-Ying , Yen Shuo-Wen , Lee Ching-Ting
Published: May 2020

In this study, poly(N-vinylcarbazole) (PVK) polymer was blended with various dimensional CdSe/ZnS core-shell quantum dots to be used as a single emissive layer of white quantum dots light-emitting diodes (WQLEDs). Besides, the nanostructured ITO/ZnO nanorod array was used as electron transport/injection layer to shorten carrier transport distance, accelerate carrier transport velocity, and enhance carrier transport surface area. Consequently, luminance and luminous efficiency were increased by the resulting increase of the carrier injection current density and the hole-electron recombination opportunity. The CIE of (0.329, 0.331) was obtained for the WQLEDs by using the weight ratio of 1.5:1.3:2.2 of the red, green, and blue (RGB) quantum dots. Compared with the WQLEDs without the nanorod array, the WQLEDs with the 1.5-µm-periodic ITO/ZnO nanorod array obtained an increased luminance of 16333 cd/m2 (compared with 7191 cd/m2) and an increased luminous efficiency of 3.13 cd/A (compared with 2.30 cd/A).
Coherent MIMO radar network enabled by photonics with unprecedented resolution
Authors: Maresca Salvatore , Scotti Filippo , Serafino Giovanni , Lembo Leonardo , Malacarne Antonio , Falconi Fabio , Ghelfi Paolo , Bogoni Antonella
Published: May 2020

The conventional concept of radar is based on stand-alone and independent apparatuses. Superior performance is possible, exploiting distributed points of view (i.e., distributed radars) and centralized data fusion, but systems based only on radio-frequency technology are not able to guarantee the requested degree of coherence and high capacity links among radars. In the current distributed systems, radars act almost independently from each other. Thus, data fusion, which must be performed on locally pre-processed information, can only exploit partial information content, harming the imaging capability of the distributed system. Here we present, to the best of our knowledge, the first extended analysis and experiment of a distributed coherent multiple input-multiple output radar system, enabled by photonics, which maximizes the information content extracted by a centralized data fusion, providing unprecedented resolution capabilities. Stepping from previous achievements, where photonics has been demonstrated in single radars, here photonics is used also for providing coherence and high capacity links among radars. The numerical analysis also demonstrated the benefits of coherent multi-band operation for sidelobe reduction, i.e., false alarms reduction.
Increasing the enhancement factor for DMD-based wavefront shaping
Authors: Nam Kibum , Park Jung-Hoon
Published: May 2020

Focusing through scattering media is a subject of great interest due to its direct impact in the field of biomedical optics. However, the greatest barrier currently limiting direct applications is the fact that most scattering media that we wish to deliver light through are dynamic. To focus or deliver light through dynamic scattering media, using a digital micromirror device (DMD) has been demonstrated to be a potential solution, as it enables fast modulation speeds. However, since a DMD is a binary amplitude modulator, the large number of controlled modes needed to acquire adequate focus enhancement has limited optimal usage. Here we demonstrate a novel (to the best of our knowledge) scheme to use the “thrown-away” components of light to effectively use a binary amplitude DMD as a binary phase modulator, thereby increasing the correction efficiency by a factor of two. Our concept can be applied to any iterative optimization algorithm and can speed up the iterative optimization process by increasing the enhancement factor, rather than the measurement or modulation speeds.
Depth Profiles of Cerebral Blood Flow Modulation
Authors: Balberg Michal , Pham Thao , Blaney Giles , Sassaroli Angelo , Fantini Sergio
Published: May 2020

Cerebral blood flow (CBF) is modulated by hypercapnia. We demonstrate, using both Acousto-optics and NIRS-CHS, that CBF modulation varies as a function of depth, and its profile is subject and manipulation dependent.
Toward Whole-Brain In Vivo Optoacoustic Angiography of Rodents: Modeling and Experimental Observations
Authors: Subochev Pavel , Smolina Ekaterina , Sergeeva Ekaterina , Kirillin Mikhail , Orlova Anna , Kurakina Daria , Emyanov Daniil , Razansky Daniel
Published: May 2020

We report on a comprehensive theoretical analysis of the optimal wavelengths for in vivo OA angiography in whole rodent brains. Governed by the competing processes of light attenuation through the brain tissues and OA signal generation due to absorption by blood, we identified three distinct spectral ranges centered around 580, 895 and 1100 nm optimally suited for imaging of vessels of different size and depth. The developed model was employed for numerical simulation of OA imaging of murine brain illustrating the effect of probing wavelength on visibility of the cerebral vasculature. In vivo imaging experiments further affirmed the capacity for whole-brain OA angiography in rodents at a wavelength of 1064nm.
Predicting Breast Cancer Treatment Response using Diffuse Optical Tomography and Ultrasound
Authors: Zhu Quing , Poplack Steve , Ademuyiwa Foluso , Young Catherine
Published: May 2020

This clinical study validates an early treatment window for predicting complete or near-complete pathological response of breast cancer patients based on pretreatment total-hemoglobin level (THb), early changes of THb and ultrasound measurements following neoadjuvant chemotherapy.
Method development and feasibility assessment for diagnosing 12 needle cores within an hour of biopsy
Authors: Xie Weisi , Glaser Adam K. , Vakar-Lopez Funda , Reder Nicholas P. , True Lawrence D. , Liu Jonathan T.C.
Published: May 2020

An ~45-minute workflow, consisting of fluorescence labeling, tissue clearing, and 3D non-destructive, open-top light-sheet (OTLS) microscopy, has been developed for diagnosis of 12 human prostate needle cores within an hour after biopsy.
Polarization Sensitive Optical Coherence Tomography-Guided Percutaneous Radiofrequency Ablation in Left Atrium of Living Swine
Authors: Zhao Xiaowei , Ziv Ohad , Mohammadpour Reza , Crosby Benjamin , Hoyt Walter J. , Jenkins Michael W. , Snyder Christopher , Laurita Kenneth R. , Rollins Andrew M.
Published: May 2020

Atrial fibrillation (AF) is the most common sustained arrhythmia in the western world. Pulmonary vein isolation (PVI) using radiofrequency ablation (RFA) is frequently conducted to treat AF. However, current PVI procedures for lesion formation are guided only with indirect information, which may lead to non-transmural lesions, and contribute to the high recurrence of AF. Therefore, direct lesion quality feedback may potentially improve PVI efficacy. To study the real-time direct guidance capability of polarization sensitive optical coherence tomography (PSOCT), a custom-designed integrated PSOCT-RFA catheter was prototyped and tested in RFA procedures in the left atria of living swine.
Journalists interviewing elite athletes: Dumb answers or bad questions?
Authors: Eljand-Kärp Viivika , Harro-Loit Halliki
Published: May 2020

Broadcasting journalists use short, ad hoc interviews for newsworthy events. Because these interviews typically last for just a few minutes, it is a challenge for both journalist and interviewee to address the audience. This study explores journalistic questioning techniques in sixteen live broadcast interviews with athletes carried out by Estonian journalists during the 2018 Olympic Winter Games plus a few examples from sports interviews collected from the Spanish, Italian, Finnish, German and American television. Analysis shows the questioning technique of journalists does not help interviewees to provide well-focused and interesting explanations. The main problems are related to the scope of the questions, blurred focus and the journalists’ inability to use listening-based questioning. As a result of the analysis, we propose a universal model that would help journalists in any field (not just sports journalism) to carry out better ad hoc questioning.
Interaction and user-generated content on online informative platforms: A comparison of journalists in Colombia, Peru and Ecuador1
Authors: Barredo-Ibáñez Daniel , Pinto-Garzón Karen Tatiana , Freundt-Thurne Úrsula , Medranda-Morales Narcisa Jessenia
Published: May 2020

Interactivity is among the main characteristics of online journalism because it helps to build bridges between the media, journalists and the users to whom the news is directed. This article, based on in-depth interviews with 35 journalists, examines the concept of interaction as understood by media sources in Colombia, Peru and Ecuador. These three countries are culturally and historically similar and have similar levels of Internet access. Most of the journalists indicated that they have adjusted their practice to incorporate some aspects of Internet-based interaction, such as social network presence and increased transparency to users. However, the media organizations for which they work have adopted few such procedures and maintain limited capacity to manage online participation. The journalists expressed their desire for the development of further ways to facilitate interaction with users.
The Age of Surveillance Capitalism: The Fight for a Human Future at the New Frontier of Power, S. Zuboff (2019)
Authors: Tortajada Iolanda
Published: May 2020

Review of: The Age of Surveillance Capitalism: The Fight for a Human Future at the New Frontier of Power, S. Zuboff (2019)

New York: PublicAffairs, 704 pp.,

ISBN 978-1-61039-570-0, h/bk, $38, p/bk, $19.99
Raymond Williams: Cultural Analyst, J. McGuigan (2019)
Authors: Gilbert Ruth
Published: May 2020

Review of: Raymond Williams: Cultural Analyst, J. McGuigan (2019)

Bristol: Intellect Books, 185 pp.,

ISBN 978-1-78938-047-7, p/bk, £22.50
Mutaciones discursivas en el siglo XXI: la política en los medios y las redes, N. Pellisser Rossell and J. M. Oleaque Moreno (eds) (2019)
Authors: Calvo Dafne
Published: May 2020

Review of: Mutaciones discursivas en el siglo XXI: la política en los medios y las redes, N. Pellisser Rossell and J. M. Oleaque Moreno (eds) (2019)

Valencia: Tirant lo Blanch, 391 pp.,

ISBN 978-8-41770-623-4, p/bk, €25
Community music as intervention: Three doctoral researchers consider intervention from their different contexts
Authors: Currie Ruth , Gibson Jo , Lam Chi Ying
Published: May 2020

There is a rising critique of the process and position of decision-making across music interventions, which has been evidenced through the MUSOC research network debates that we, as doctoral students, have participated in. In this article, we specifically discuss ‘intervention’ as ‘deliberate strategies that seek to enable people to find self-expression through musical means’ (Bartleet and Higgins 2018: 3). We offer three perspectives from three different intervention contexts: community music in schools, organizational settings and music-making workshops. Through this article, we share and reflect on our experience with intervention and decision making within our practice. We give specific focus to: how intentions and motivations underpinning interventionist practice manifest in different contexts; how this is currently informed by the decision-making structures through which community music is practised in each context; and, the extent to which dominant modes of practice have potential to disempower participants, including how they are reinforced and re-enacted through this process. Finally, we suggest that how we talk about intervention across peers, and how we enact it through our practice as practitioners and researchers is possibly misaligned. This warrants further consideration if explorations of the term ‘intervention’ are to feed into discussion and action for responsible practice.
Claude Jutra’s Surfacing (1981) through visual spectacles: Framing female body, voyeurism and paranoia
Authors: Ishaque Nausheen , Riaz Saba
Published: May 2020

This article examines Claude Jutra’s 1981 film adaptation of Margaret Atwood’s Surfacing in terms of its focus on female body, voyeurism and paranoia. The psychoanalytic perspective of the feminist film theory, with its emphasis on visual pleasure, narcissism, the male gaze, scopophilia, fetishization of the female, the oedipal nature of the narrative and female subjectivity, provides a pragmatic groundwork for the theoretical underpinning of this study. In the same way, the film apparatus, such as editing and camera work, provides a semiotic impetus to the spectator to identify with the perfect male, and not with the distorted female. With its focus on various scenes, generic codes and aspects of the film, the paper furthermore sees how Jutra’s production validates the prejudices of the classical film narrative in the context of the female image, sexual difference, female desire and stereotyped female paranoia. Despite its narrative focus on the quest of a female protagonist, Jutra’s film conforms to the traditional model of the classical cinema wherein the woman is no more than a signifier – an entity that signifies things in relation to men only.