bluuebunny/crossref_metadata_2025 huggingface dataset:
Logística Urbana desde la perspectiva del Agente Generador de Viajes
Authors: León Oscar Palacio
Published: April 2019

Introducción: La logística urbana es la encargada de planificar y gestionar los servicios de una ciudad, a fin de atraer inversiones y retener actividades productivas. En donde, las estrategias de negocio del tipo ganar-ganar, son uno de los tantos medios útiles con que cuenta la administración de la ciudad, para viabilizar la retención de empresas extendidas productivas y de servicio, que se pueden estructurar desde la gestión del inventario conjunto, siguiendo uno de tres enfoque de dirección, a saber: i) Agente generador de carga; ii) Agente regulador de carga; y iii) Agente generador de viajes.
Objetivo: Diseñar una estrategia de administración del inventario conjunto en estado de incertidumbre y ambigüedad, con respecto al agente generador de viajes en la empresa extendida urbana de economía compartida.
Metodología: El desarrollo de la investigación se llevó a cabo mediante la ejecución de una estructura operacional de análisis de eficiencia técnico-económica y financiera, con la que se llevó a cabo el diseño de la estrategia de administración del inventario conjunto en condiciones de incertidumbre y ambigüedad, a fin de identificar los aspectos en que influye el agente generador de viajes en la empresa extendida urbana de economía compartida.
Resultados: Con el análisis de la eficiencia técnico-económica y financiera obtenida se demuestra que, una forma de gestionar el inventario conjunto en estado de incertidumbre y ambigüedad, es el cálculo centrado en la econometría con aplicación en los juegos de transferencia de utilidad, basando su viabilidad, elegibilidad y prioridad en las matemáticas financieras borrosas.
Conclusiones: Por lo general, la gestión del inventario conjunto se da en el marco de la negociación concretada, entre los Agentes Generadores tanto de Carga como de Viajes, a fin de balancear en equidad las Estrategias contrapuestas Push y Pull, en que soportan su integración como empresa extendida urbana.
Seria possível uma epistemologia freiriana decolonial? Da “Cultura do Silêncio” ao “Dizer a Sua Palavra”
Authors: Loureiro Camila Wolpato , Pereira Thiago Ingrassia
Published: April 2019

A colonialidade está presente na construção da mente e do imaginário latino-americano. Por meio da análise bibliográfica dos estudos pós-coloniais, subalternos e decoloniais, abordam-se as diferentes formas de representação da colonialidade, tendo a “Cultura do silêncio” proposta por Paulo Freire como expressão possível dessa relação de opressão. Dessa forma, objetiva-se pensar o conceito de “Cultura do silêncio” como uma representação da colonialidade do ser, na qual os sujeitos são subjugados e retirados do direito de pronunciamento crítico do (seu) mundo, propondo o conceito “Dizer a sua palavra” como uma forma de práxis decolonial. Consideramos que a ação de “Dizer a sua palavra” passa a ser um ato de desobediência epistêmica e de humanização dos corpos e mentes dos(das) subalternizados(as)/colonizados(as)/oprimidos(as).
Factors Associated With Batterer Intervention Program Attrition
Authors: Priester Mary Ann , Kulkarni Shanti , Mennicke Annelise , Bell Bethany A.
Published: April 2019

Batterer intervention programs' (BIPs) curriculum have been criticized for their one-size-fits-all approach to rehabilitation with recent research suggesting specialized and client-centric approaches to batterer intervention may be more effective than traditional programming. Adverse childhood experiences (ACEs) have been examined as a risk factor for intimate partner violence (IPV) perpetration and numerous studies suggest a relationship between ACEs and low mental health treatment engagement. However, absent from the conversation is how ACEs may influence BIP treatment engagement and more specifically how ACEs influence BIP program attendance and attrition. The current study used administrative data from a sample of 268 men enrolled in a county-operated BIP to explore this question. BIP participants who experienced any ACEs, only household dysfunction ACEs, and/or both household dysfunction ACEs and child abuse/neglect ACEs had decreased odds of BIP attrition compared to participants with no ACEs. These findings have practical implications regarding screening, service delivery, and BIP curricula and highlight additional research needed on this topic.
The Mediating Role of Emotion Regulation Difficulties in the Relationship Between Self-Compassion and OCD Severity in a Non-Referred Sample
Authors: Chase Tannah E. , Chasson Gregory S. , Hamilton C. Elizabeth , Wetterneck Chad T. , Smith Angela H. , Hart John M.
Published: April 2019

Self-compassion involves extending kindness and understanding to one's self. Research has demonstrated inverse relationships between self-compassion and maladaptive constructs associated with obsessive–compulsive disorder (OCD), including emotion regulation (ER) difficulties. The current study sought to explore associations between self-compassion, ER difficulties, and OCD severity. Data were collected at the International Obsessive–Compulsive Disorder Foundation convention from 62 attendees who reported having a diagnosis of OCD (51% male, mean age 35.9 years). Findings demonstrated that self-compassion and ER difficulties were associated with overall OCD severity. Results also indicated that ER difficulties mediated relationships between self-compassion and overall OCD severity, as well as the severity of two OCD symptom dimensions, responsibility for harm and unacceptable thoughts. These findings suggest that self-compassion and ER difficulties may be involved in the maintenance and severity of OCD.
Evaluating the Automat Usage for Bottom Hemming Operation in Terms of Process Time and Quality
Authors: Boz Serkan
Published: April 2019

Apparel
industry, which has a major impact on the world trade, has been struggling with
a competitive environment with challenging conditions like the other
labor-intensive sectors all over the world. Following the latest technological
developments and efforts of keeping up with these activities would affect the
operational efficiency in a positive manner. Therefore, being able to adapt
these developments to the companies becomes of great importance in today's
business world. This study investigates the operation of bottom hemming of
casual trousers. Despite the fact that bottom hemming is not defined as a
difficult process, it requires manual skills. The difficulty of controlling the
cylindrical part of the bottom under the machine head (presser foot), especially
for the narrow-bottomed trousers, may cause prolonged sewing process times and
also some undesirable quality problems. In this study, bottom hemming operation
is performed by using both classical method and recently developed bottom
hemming automat, to highlight the comparison between the manual hemming of
denim trousers and usage of automation for this process in terms of duration
and quality. Thus, the advantageous method is defined, from the point of
productivity (process time) and quality. In this study, it’s observed that 33.34% time saving and eliminations of
quality problems by using automat for bottom hemming operation.
FAKTOR YANG MEMPENGARUHI KELUHAN MUSCULOSKELETAL DISORDERS (MSDs) PADA PEKERJA INFORMAL
Authors: Tjahayuningtyas Aulia
Published: April 2019

Musculoskeletal disorders (MSDs) is a disorder or damage to the joints, ligaments, muscles and other skeletal systems due to unnatural or awkward body position especially if carried on for a long duration. Complaints of MSDs are influenced by internal factors (age, work durration, exercise habits, and body mass index) and external factors (work position and workload). The purpose of this study was to analyze the relationship between internal and external factors on complaints of MSDs to workers in the informal sector. The research design was crossectional approach. Data was analyzed by chi-square. The results of this study to 38 workers show that age (p = 0.102), exercise habits (p = 0.297), BMI (p = 0.332) and work positions (p = 0.864) have no relation to MSDs complaints while work durration (p = 0.019) and energy expenditure (p = 0.000) has a relationship with MSDs complaints. The conclusions of this research was that workload durration and cooking workload have a relationship with the complaints of MSDs in informal workers. Based on the level of MSDs complaint, mostly, workers felt the complaint on the right hand wrist (86%) and right foot (68%). It is recommended to informal workers to stretch the muscles on the sidelines of doing the work so that MSDs complaints can be minimized.Keywords: cooking work load, informal worker, manufacturing industry of tofu, subjective complaint of MSDs
Evaluasi Model Intervensi Apoteker Terhadap Peningkatan Pengetahuan Penggunaan Obat Pada Ibu Rumah Tangga Di Bantaran Sungai Kemuning Banjarbaru
Authors: Srikartika Valentina Meta , Intannia Difa
Published: April 2019

ABSTRAK Praktik pengobatan sendiri atau swamedikasi di Kalimantan Selatan relatif tinggi. Masyarakat pelaku swamedikasi sangat rentan menggunakan obat tidak rasional disebabkan tidak adanya pemberian informasi penggunaan obat yang benar. Beberapa metode dapat diimplementasikan sebagai sarana Apoteker untuk mengedukasi masyarakat terkait penggunaan obat. Penelitian ini bertujuan untuk mengevaluasi peningkatan pengetahuan ibu rumah tangga di daerah bantaran sungai Kemuning Banjarbaru akan penggunaan obat setelah diberikan intervensi oleh Apoteker dalam bentuk CBIA dan booklet. Penelitian ini merupakan penelitian non-ekperimental dengan desain penelitian cross-sectional yang dilakukan terhadap 33 responden kelompok CBIA dan 30 responden kelompok booklet. Tingkat pengetahuan sebelum dan sesudah intervensi diukur dengan menggunakan kuisioner. Rata-rata skor pretest kelompok CBIA dan booklet adalah 3.67 dan 5.43, sedangkan rata-rata skor post-test kelompok CBIA dan booklet adalah 6.87 dan 8.97 (p<0.01). Perbandingan rata-rata peningkatan skor pengetahuan setelah intervensi CBIA adalah 3.21 ± 2.47 dan booklet adalah 3.53 ± 1.89 (p=0.567). Dapat disimpulkan bahwa model intervensi CBIA dan booklet dapat meningkatkan pengetahuan penggunaan obat secara signifikan, dan kedua metode tersebut sama baiknya untuk digunakan sebagai metode intervensi apoteker dalam meningkatkan pengetahuan pasien akan pengobatan. Kata kunci: CBIA, booklet, pengetahuan, obat, Apoteker  ABSTRACT The self-medication practice in South Kalimantan is relatively high. People who are self-medicated are very vulnerable to irrational drug use because there is no provision of information on the correct drug use. Several methods can be implemented by pharmacists to educate the public regarding drug use. This study aims to evaluate the increase in drug use knowledge of housewives in the Kemuning riverbank area of Banjarbaru after being given intervention by Pharmacists in the form of CBIA and booklets. This research is a non-experimental study with a cross-sectional research design conducted on 33 CBIA group respondents and 30 respondents booklet groups. The level of knowledge before and after the intervention was measured using a questionnaire. The average pretest scores of CBIA and booklet groups were 3.67 and 5.43, while the average post-test scores of CBIA and booklet groups were 6.87 and 8.97 (p <0.01). Comparison of the average increase in knowledge score after CBIA intervention was 3.21 ± 2.47 and the booklet was 3.53 ± 1.89 (p = 0.567). It can be concluded that CBIA and booklet intervention models can significantly improve knowledge of drug use, and both methods are equally good for use as pharmacist intervention methods in increasing patient knowledge of treatment. Keywords: CBIA, booklet, knowledge, medicine, pharmacist
Faktor-Faktor yang Mempengaruhi Kepatuhan Pasien HIV/AIDS Rawat Jalan dalam Pengobatan Terapi Antiretroviral (ART) di Rumah Sakit Dr.H.Moch.Ansari Saleh Banjarmasin
Authors: Srikartika Valentina Meta , Intannia Difa , Aulia Restu
Published: April 2019

ABSTRAK             Acquired Immune Deficiency Syndrome (AIDS) merupakan kumpulan gejala penyakit yang disebabkan oleh Human Immunodeficiency Virus (HIV). Tatalaksana terapi HIV/AIDS adalah dengan pemberian antiretroviral (ARV) seumur hidup sehingga kepatuhan mengkonsumsi obat merupakan faktor penting untuk keberhasilan terapi. Penelitian ini bertujuan untuk mengevaluasi  kepatuhan pasien HIV/AIDS alasan pasien tidak patuh mengkonsumsi obat. Penelitian ini juga bertujuan untuk mengevaluasi hubungan antara faktor keyakinan, faktor dukungan sosial, faktor pendidikan, efek samping obat yang dialami pasien dengan kepatuhan. Desain penelitian yang digunakan adalah cross sectional. Penelitian dilakukan di poliklinik VCT RS Dr. H. Moch. Ansari Saleh Banjarmasin. Kepatuhan pasien diukur dengan menggunakan kuesioner MMAS-8 dan faktor kepatuhan diukur dengan kuesioner ACTG. Hasil analisis kepatuhan pada penelitian menunjukkan bahwa 32 (51,6%) pasien memiliki nilai kepatuhan yang tinggi. Hasil penelitian juga menunjukkan bahwa pasien memiliki keyakinan yang tinggi sebanyak 34 pasien (54,8%), pasien memiliki dukungan sosial yang tinggi sebanyak 45 pasien (72,6%), pasien yang tidak merasakan efek samping sebanyak 33 pasien (53,2%), dan alasan pasien lupa mengkonsumsi obat tertinggi adalah pasien merasa keadaan yang dialaminya baik-baik saja sebanyak 14 orang (46,6%). Terdapat korelasi yang signifikan antara kepatuhan dengan efek samping obat (p=0,002, r= -0.326). Kata kunci: kepatuhan, faktor yang mempengaruhi kepatuhan, MMAS-8, ACTG, HIV/AIDS     ABSTRACT Acquired Immune Deficiency Syndrome (AIDS) is a set of illness symptoms, which is caused by Human Immunodeficiency Virus (HIV). As the HIV/AIDS therapy has to be consumed over a lifetime for the patients, the compliance on taking antiretroviral (ARV) medications is essential. This study aims to evaluate the compliance of HIV/AIDS outpatients and the reasons of patients incompliance. This study also examine the correlation between the beliefs, social support, education, and adverse medication events factors with ARV medication’s incompliance. The study design was cross sectional study design. The research was done in policlinic of VCT Dr. H.MOCH.SALEH hospital, Banjarmasin. The incompliance was obtained by having the ACTG questioners. The results of the compliance analysis in this study was 32 (51,6%) patients have a high compliance score. The result also showed that 34 patients (54.8%) had great belief, 45 patients (72.6%) had great social support and 33 patients (53.2%) did not get the drug side effects. Furthermore, the reason not to comply with the medicine was due to their conditions which were considered fine without medication (34 patients (37.4%)). The correlation between compliance and the drug side effects was significance (p=0,002, r= -0.326) Keywords: compliance, affected factors compliance, MMAS-8, ACTG, HIV/AIDS
A Survey of College Student Dormitory Lifestyle and Related Management Strategies
Authors: Wei Wenzhu , Chen Li
Published: April 2019

A systematic survey on the life-style of college undergraduate dormitory of a local public university finds that, most of the time, undergraduates “amuse themselves” in the dorms and mutual learning and communication time is relatively insufficient. Students in the dorms have a higher expectation on interpersonal relationship. However, in reality, there exists the problem that the affection between them is indifferent. Besides, when they come into conflicts, they are incapable of resolving the conflicts through a normal channel. Furthermore, students are relatively satisfied with the life service in dormitory management, while they are not satisfied with the hardware facilities and the rules and regulations. To improve the management level of college student dormitory and promote development of students, it is necessary for the department of college dormitory management to strengthen construction of the physical environment, develop an organic dormitory interpersonal network and establish the dormitory organizational structure and institutional norms in which students can participate. Above all, the department of dormitory management needs to establish the system of dormitory education to help students carry out effective education in life.
El reto de incorporar indicadores en los sistemas de evaluación y seguimiento de los Planes Regionales de Ordenación Territorial en España
Authors: Cordera Rubén , Nogués Soledad , González-González Esther
Published: April 2019

El progresivo proceso de europeización de la planificación territorial ha promovido la aparición de nuevos objetivos y mecanismos de control de los planes de ordenación, como son el desarrollo sostenible y los sistemas de evaluación y seguimiento. Sin embargo, en España, a diferencia de otros países que cuentan con directrices o guías nacionales, esta inclusión no se ha realizado de manera sistemática. Este artículo tiene como objetivo comprobar hasta qué punto y cómo se está integrando la evaluación y seguimiento de los planes territoriales españoles prestando especial atención al uso de sistemas de indicadores. La revisión de los planes actuales permite afirmar que España está todavía dando sus primeros pasos, dado que, de las 17 comunidades autónomas, diez contemplan sistemas de evaluación y seguimiento específicos, mediante la elaboración de planes o informes, y solo cinco los han desarrollado e implementado incluyendo el uso de sistemas de indicadores. Además, las metodologías empleadas difieren significativamente en cuanto a qué debe medirse, es decir, en cómo se conceptualiza la sostenibilidad, y al número y tipo de indicadores seleccionados. De cara al futuro se recomienda tender a una mayor convergencia en la definición de las metodologías de evaluación y seguimiento que contemplen el uso de indicadores e índices sintéticos, con el fin de facilitar su comparación entre distintos ámbitos territoriales, potenciar sinergias y optimizar el uso de recursos.
Characterization of the complete plastomes of two flowering epiparasites (Phacellaria glomerata and P. compressa, Santalaceae, Santalales): gene content, organization and plastome degradation
Authors: Guo Xiaorong , Liu Changkun , Wang Hengchang , Zhang Guangfei , Yan Hanjing , Su Wenhua , Ji Yunheng
Published: April 2019

Backgrounds: The transition to a heterotrophic lifestyle triggers reductive evolution of plastid genome (plastome) in both photosynthetic and non–photosynthetic parasites. A plant parasite parasitizing another plant parasite is referred to as epiparasitism, which is extremely rare in angiosperms. In despite of the particularly special lifeform of epiparasitic plants, their plastomes have not been characterized to date. Sequending such plastomes may enable new insights into the evolutionary pathway of plastome degradation associated with parasitism.
Results: In this study, we generated complete plastomes of Phacellaria compressa and P. glomerata (Santalaceae, Santalales) through Illumina shotgun sequencing. Plastome assembly and comparison indicated that plastomes of both species exhibit the quadripartite structure typical of angiosperms, and that they possess similar size, structure, gene content, and arrangement of genes to other hemiparasites in Santalales, especially to those hemiparasites in Santalaceae. The plastomes of P. compressa and P. glomerata were characterized by the functional loss of plastid–encoded NAD(P)H–dehydrogenase and infA genes, which strongly coincides with the general pattern of plastome degradation observed in Santalales hemiparasites.
Conclusion: Our study demonstrates that the shift to epiparasitism and reduced vegetative bodies in P. compressa and P. glomerata do not appear to cause any unique plastome degradation compared with their closely related hemiparasites. The epiparasitic lifestyle or an endophytic growth form observed in these two epiparasites may have limited impact on the reductive modification of their plastomes.
An analysis of the magnetic behavior of olivine and garnet substitutional solid solutions
Authors: Geiger Charles A. , Grodzicki Michael , Dachs Edgar
Published: April 2019

The low-temperature magnetic properties and Néel temperature, TN, behavior of four silicate substitutional solid solutions containing paramagnetic ions are analyzed. The four systems are: fayaliteforsterite olivine [Fe22+SiO4-Mg2SiO4], and the garnet series, grossular-andradite [Ca3(Alx,Fe1−x3+)2Si3O12], grossular-spessartine [(Cax,Mn1−x2+)3Al2Si3O12], and almandine-spessartine [(Fex2+,Mn1−x2+)3Al2Si3O12]. Local magnetic behavior of the transition-metal-bearing end-members is taken from published neutron diffraction results and computational studies. TN values are from calorimetric heat capacity, CP, and magnetic susceptibility measurements. These end-members, along with more transition-metal-rich solid solutions, show a paramagnetic to antiferromagnetic phase transition. It is marked by a CP λ-anomaly that decreases in temperature and magnitude with increasing substitution of the diamagnetic component. For olivines, TN varies between 65 and 18 K and TN for the various garnets is less than 12 K. Local magnetic behavior can involve one or more superexchange interactions mediated through oxygen atoms. TN behavior shows a quasi-plateau-like effect for the systems fayalite-forsterite, grossular-andradite, and grossular-spessartine. More transition-metal-rich crystals show a stronger TN dependence compared to transition-metal-poor ones. The latter may possibly show superparamagnetic behavior. (Fex2+,Mn1−x2+)3Al2Si3O12 garnets show fundamentally different magnetic behavior. End-member almandine and spessartine have different and complex interacting local superexchange mechanisms and intermediate compositions show a double-exchange magnetic mechanism. For the latter, TN values show negative deviations from linear interpolated TN values between the end-members. Double exchange seldom occurs in oxides, and this may be the first documentation of this magnetic mechanism in a silicate. TN behavior may possibly be used to better understand the nature of macroscopic thermodynamic functions, CP and S°, of both end-member and substitutional solid-solution phases.
Price-volume relation behavior around structural breaks in Kuwait Boursa
Authors: A. Abdulsalam Fayez , kh. Bouresli Amani
Published: April 2019

This study attempts to conduct a comprehensive investigation of the price-volume relation using daily stock prices of all publicly traded firms in Kuwait Boursa over the period 2005–2017. The aim is to provide evidence from an emerging market on the information arrival hypothesis, which is explained by the mixture of distribution and the sequential information arrival hypotheses. The investigation covered two main structural events; the 2008 financial crisis and the activation of Kuwait’s New Securities Law in 2010 (CMA). The GARCH-ARCH test revealed a positive contemporaneous relation between trading volume and market return, which implies that previous information shocks affect current returns and imply that Kuwait stock market is weakly efficient. When trading volume is included in the variance equation in the GARCH model, the test revealed that new information arrival is not simultaneously available to all traders and it takes time to observe, providing support to the sequential information arrival hypothesis (SAIH). Finally, there was no change in the price-volume relation around the two events and urgent assessment of the new market reform is recommended.
Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity
Authors: An Jie , Sheikh M. Saeed
Published: April 2019

Trastuzumab is a humanized monoclonal antibody that is approved for the treatment of breast and gastric malignancies. Although it has shown promise as a biotherapeutic, its cardiotoxicity remains a major concern. Genotoxic anticancer anthracyclines such as doxorubicin and epirubicin are also known for their cardiotoxic effects. However, trastuzumab and anthracyclines are suggested to mediate cardiotoxicity via different pathways. The available lines of evidence suggest that trastuzumab can exacerbate the cardiotoxic effects of anthracyclines and thus, prior exposure to anthracyclines is regarded as one of the risk factors for trastuzumab-induced cardiotoxcity. Although it is generally believed that the trastuzumab-induced cardiotoxic effects are reversible, various preclinical studies have revealed its apoptotic effects on cardiomyocytes. Thus, the issue of the reversibility of its cardiotoxic effects remains to be fully resolved. This article discusses various mechanisms that have been proposed for the cardiotoxic effects of trastuzumab and the potential risk factors that can lead to cardiotoxicity. The recently approved anti-HER2 monoclonal antibodies including pertuzumab and ado-trastuzumab (T-DM1) are also discussed.
A BRCA1 Frame Shift Mutation in Women of Kurdish Jewish Descent
Authors: Zick Aviad , Cohen Sherri , Hamburger Tamar , Goldberg Yael , Zvi Naama , Sagi Michal , Peretz Tamar
Published: April 2019

Hereditary cancer comprises more than 10% of all breast cancer cases. In patients with a family history suggestive of a hereditary component, a mutation is often identified in the high penetrant genesBRCA1andBRCA2. Several founder mutations have been detected in some Jewish communities, yet noBRCA1/2founder mutation had been known in Kurdish Jews. Here, we describe the validation of a 22 hereditary cancer gene panel and aBRCA1mutation found in 4 women from 2 unrelated Kurdish Jewish families utilizing this gene panel.

A panel spanning the coding sequences of 22 familial cancer-related genes was planned. Genomic DNA was taken to create libraries using this panel, which were then sequenced using the Ion Torrent PGM. The panel's validity in detecting mutations was tested on 25 samples with previously identified point mutations in theBRCA1,BRCA2,MLH1andPMS2genes; the panel did not test for large deletions or insertions. All previously identified mutations were detected. Next, a different set of 40 cancer patients of Kurdish Jewish descent diagnosed with cancer before the age of 50 years was tested. We identified theBRCA1mutation,c.224_227delAAAG(dbSNP ID rs80357697), in 4 women from 2 unrelated Jewish Kurdish families. The probands were diagnosed with cancer at a young age and had significant family history, suggesting a founder mutation in this population. We suggest testing Kurdish Jewish women with a personal or family history of breast and/ or ovarian cancer for this mutation.
Collaborative Learning Dalam Upaya Peningkatan Keaktifan Mahasiswa Pada Proses Pembelajaran
Authors: Respati Yudit Ayu
Published: April 2019

Perubahan jaman menuntut peserta didik menjadi lebih aktif dan kreatif. Namun metode pembelajaran yang diterapkan di perguruan tinggi masih menggunakan metode tradisional, yaitu pengajar memiliki peran penting dalam proses pembelajaran. Akibatnya, peserta didik hanya menjadi objek dalam sistem pembelajaran yang membuat mereka menjadi pasif. Peserta didik tidak memiliki inisiatif untuk membangun sendiri pengetahuan mereka karena memang kurangnya kesempatan yang mereka untuk terlibat atau berpartisispasi dalam proses pembelajaran. Active learning adalah model pembelajaran yang dianggap efektif untuk meningkatkan keaktifan peserta didik dalam proses pembelajaran. Salah satu cara pengaplikasian model pembelajaran ini adalah dengan menerapkan metode collaborative learning, dimana perspektif dari metode ini adalah seseorang dikatakan belajar apabila orang tersebut terlibat aktif dalam proses pembelajaran.Kata kunci: Active Learning, Collaborative Learning  Abstract: Increasing Student Participation Through Collaborative Learning. Changes in time require students to be more active and creative. But, learning method that applied in higher education still use traditional method, which is lecturer has an important role in the learning process. As a result, students only become objects in the learning system that makes them passive. They don’t have initiative to build their own knowledge because of the lack of opportunities that they are involved in or participating in the learning process. Active learning is a learning model that is considered effective to increase the activity of the students in the learning process. One way to apply this learning model is to apply collaborative learning method, where the perspective of this method is that someone is said to learn if the person is actively involved in or participates in the learning process.        Keyword: Active Learning, Collaborative Learning
Proteomic Analysis of Urinary Microvesicles and Exosomes in Medullary Sponge Kidney Disease and Autosomal Dominant Polycystic Kidney Disease
Authors: Bruschi Maurizio , Granata Simona , Santucci Laura , Candiano Giovanni , Fabris Antonia , Antonucci Nadia , Petretto Andrea , Bartolucci Martina , Del Zotto Genny , Antonini Francesca , Ghiggeri Gian Marco , Lupo Antonio , Gambaro Giovanni , Zaza Gianluigi
Published: April 2019

Background and objectives

Microvesicles and exosomes are involved in the pathogenesis of autosomal dominant polycystic kidney disease. However, it is unclear whether they also contribute to medullary sponge kidney, a sporadic kidney malformation featuring cysts, nephrocalcinosis, and recurrent kidney stones. We addressed this knowledge gap by comparative proteomic analysis.

Design, setting, participants, & measurements

The protein content of microvesicles and exosomes isolated from the urine of 15 patients with medullary sponge kidney and 15 patients with autosomal dominant polycystic kidney disease was determined by mass spectrometry followed by weighted gene coexpression network analysis, support vector machine learning, and partial least squares discriminant analysis to compare the profiles and select the most discriminative proteins. The proteomic data were verified by ELISA.

Results

A total of 2950 proteins were isolated from microvesicles and exosomes, including 1579 (54%) identified in all samples but only 178 (6%) and 88 (3%) specific for medullary sponge kidney microvesicles and exosomes, and 183 (6%) and 98 (3%) specific for autosomal dominant polycystic kidney disease microvesicles and exosomes, respectively. The weighted gene coexpression network analysis revealed ten modules comprising proteins with similar expression profiles. Support vector machine learning and partial least squares discriminant analysis identified 34 proteins that were highly discriminative between the diseases. Among these, CD133 was upregulated in exosomes from autosomal dominant polycystic kidney disease and validated by ELISA.

Conclusions

Our data indicate a different proteomic profile of urinary microvesicles and exosomes in patients with medullary sponge kidney compared with patients with autosomal dominant polycystic kidney disease. The urine proteomic profile of patients with autosomal dominant polycystic kidney disease was enriched of proteins involved in cell proliferation and matrix remodeling. Instead, proteins identified in patients with medullary sponge kidney were associated with parenchymal calcium deposition/nephrolithiasis and systemic metabolic derangements associated with stones formation and bone mineralization defects.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2019_04_24_CJASNPodcast_19_06_.mp3
Manejo del estrés; resultado de dos intervenciones: cognitivo conductual y yoga, en estudiantes irregulares de medicina
Authors: Ortiz Leóna Silvia , Sandoval Bosch Elvira , Adame Rivas Solymar , Ramírez Avila Claudia Erika , Jaimes Medrano Aurora Leonila , Ruiz Ruisánchez Arturo
Published: April 2019

Introducción: El estrés durante la carrera de medicina para algunos estudiantes tiene un impacto negativo que repercute en un bajo rendimiento académico, síntomas de ansiedad y depresión. Las intervenciones psicológicas y de yoga han mostrado utilidad en la reducción de los síntomas psicopatológicos y el desarrollo de habilidades físicas y mentales.
Objetivo: Evaluar si las intervenciones de un taller cognitivo conductual y un taller de yoga disminuyen el estrés, síntomas depresivos y ansiosos en estudiantes de la licenciatura de Médico Cirujano de la Facultad de Medicina.
Método: Ensayo clínico controlado aleatorizado en la Facultad de Medicina C.U. El tipo de muestreo fue porconveniencia de los alumnos recursadores de al menos alguna asignatura de primero y segundo año de medicina. Se aplicaron los inventarios de Beck para ansiedad (BAI) y depresión (BDI), para seleccionar a los estudiantes con un nivel de severidad leve, la asignación de los alumnos fue aleatoria para cada una de las intervenciones, en las que al inicio y al final se utilizó el perfil de estrés de Novack para evaluar la reducción de estrés.
Resultados: Se observó una reducción de los síntomas depresivos y ansiosos en ambas intervenciones (p < 0.005), el grupo del taller cognitivo-conductual presentó además una reducción de las manifestaciones delperfil estrés, lo que sugiere que los alumnos lograron estrategias de afrontamiento eficaces, visualizando los estresores como retos o problemas a resolver, enfrentar y también enfocarse en los aspectos positivos de su persona. En el grupo del taller de yoga se observaron sentiaumentos significativos en la frecuencia de descanso adecuado, sueño y relajación.
Conclusiones: Se considera importante brindar estrategias para el manejo del estrés en los estudiantes de medicina, con la finalidad de favorecer no sólo el bienestar integral del alumno, sino como profesional de la salud en la promoción de estilos de vida saludables.
Revisión sistemática del póster de investigación: ¿lo hemos hecho bien todo este tiempo?
Authors: Pierdant Pérez Mauricio , Hernández Arteaga Adrián Alexis , Álvarez Pinedo Alfredo , Patiño López María Isabel , Ledezma Bautista Iván , Gordillo Moscoso Antonio Augusto
Published: April 2019

Introduccion: El cartel de investigación (póster) es una infografía impresa que tiene la función de mostrar el proceso de una investigación científica y que cumple con ciertas características específicas. En la actualidad es muy ambigua la forma de realizarlos y evaluarlos, por lo que surge la necesidad de establecer una forma consensuada de elaboración y así lograr que se tenga un modelo y guía apropiada con base en lo que la literatura nos ofrece. Objetivo: establecer criterios para la elaboración de pósters de investigación, a partir de la revisión de la literatura que nos presente lineamientos guía. Metodo: La búsqueda de información se realizó en fuentes de información electrónicas: metabuscadores (PubMed, Bireme [BVS], Trip Database y Búsqueda de Información Global [BIG] [recurso UASLP]), y bases de datos multidisciplinarias y especializadas en el área de la salud (Academic Search Complete, Springer Link, Wiley Online Library, Web of Science, Scopus y Medic Latina). Los resultados fueron exportadas y organizadas dentro del gestor bibliográfico Zotero. Resultados: La revisión de la literatura mostró diferencias entre cada autor, así como el uso indiscriminado de consejos y puntos de vista personales que no agregaban valor académico, ya que no contaban con la bibliografía necesaria para ser sustentados, también nos permitió encontrar la información adecuada con el suficiente respaldo bibliográfico para emitir una recomendación global para la realzación de un póster de investigación. Conclusiones: La estandarización del formato del póster de investigación nos abre camino a un mejor desempeño en la forma de comunicación de un trabajo científico. Además, permite implementar un correcto criterio de evaluación por parte de las instituciones que llevan a cabo este tipo de actividades dentro de los programas en congresos y conferencias, también asegura que el póster cuente con los elementos necesarios para entender este, sin la necesidad de un ponente a cargo.
Pensamiento crítico en profesionales de la salud: ¿lo estamos enseñando y evaluando?
Authors: Sánchez-Mendiola Melchor
Published: April 2019

Los profesionales de la salud con frecuencia trabajamos en condiciones que nos ponen en el borde de cometer faltas éticas y lapsos de profesionalismo.Recordemos que ser un profesional de la salud en la actualidad implica no solamente poseer conocimientos esotéricos que el resto de la sociedad no tiene, sino que implica regresar al significado original de la palabra “profesional”, sostenernos con los pies firmes en el terreno de la integridad e identidad profesional, al aplicar y vivir los valores intrínsecos a la profesión médica.
La Carta de Jamaica Base de la Construcción de América Latina
Authors: Cacua Prada Antonio
Published: April 2019

El presente texto trata sobre la epístola más citada, pero poco leída, producida por el talento genial del Padre de la Patria; precisamente hace doscientos años, el miércoles 6 de Septiembre de 1815 en la ciudad de Kingston, capital de la isla de Jamaica, entonces posesión inglesa, hoy república independiente, el derrotado, atribulado y desesperado General Simón José Antonio de la Santísima Trinidad Bolívar y Palacios de Aguirre Ponte Andrade y Blanco, dictó el documento más trascendental de su fecunda existencia a su secretario, el Coronel Pedro Briceño Méndez: La Carta de Jamaica.
COMMUNITY EDUCATION IN THE DEVELOPMENT OF THE COMMUNITY
Authors: Ardiwinata Jajat S. , Mulyono Dinno
Published: April 2019

Community education is a sustainable process in the community, built with awareness and sustained participation, in an effort to build a new understanding and concept to improve the quality of life of the community itself. Community education is now moving back into building and developing societies with the same approach as the hundreds and centuries-old approach to the prosperity of society. With the right theoretical framework, the right approach and the right program implementation models, community education can grow and develop into a power in education to build a better Indonesian society. Critical pedagogical theory and so forth is the main foundation in the development of concepts and subsequent thoughts related to public education.
USE OF DIGITAL ENCYCLOPEDIA MEDIA TO DEVELOP COGNITIVE ASPECTS OF EARLY CHILDHOOD
Authors: Supriatin Dian
Published: April 2019

Abstract Early childhood education is essentially education organized with the aim to facilitate the growth and development of children as a whole. Cognitive development refers to the child's development in thinking and the ability to give reasons. Digital encyclopedia media is one of the supporting activities in playing, because through these media children can find out a lot of things by looking at pictures, writing, listening to sounds, also can grow cognitive development or knowledge of children about everything that is found or not around their environment .The research method used in this study is descriptive with qualitative analysis with data collection techniques through observation of four students with age groups 5 to 6 years and interviews with two teachers, documentation and literature. The objectives of this study are: (1) to describe the planning of using digital encyclopedia media to develop cognitive aspects of early childhood, (2) to know the use of digital encyclopedia media in developing cognitive aspects of early childhood, (3) knowing the results of the application of media encyclopedia digital in developing cognitive aspects of early childhood (4) knowing the factors that become difficulties or obstacles in the use of digital encyclopedia media. Keywords: Early Childhood, Cognitive Development, Digital Media Encyclopedia
PENDEKATAN KONSTURKTIVISME DENGAN MODEL PEMBELAJARAN GENERATIF GUNA MENINGKATKAN KEMAMPUAN KOMUNIKASI DAN KONEKSI MATEMATIS SERTA SELF EFFICACY MAHASISWA CALON GURU DI KOTA CIMAHI
Authors: Minarti Eva Dwi , Nurfauziah Puji
Published: April 2019

Tujuan penelitian ini adalah untuk menelaah apakah peningkatan kemampuan komunikasi dan koneksi matematis mahasiswa calon guru yang belajar menggunakan pendekatan konstruktivisme dengan model pembelajaran generatif lebih baik dibandingkan dengan mahasiswa yang belajar dengan pembelajaran biasa, serta untuk mengetahui apakah terdapat hubungan antara kemampuan komunikasi dan koneksi matematis dengan self efficacy mahasiswa calon guru. Metode yang digunakan dalam penelitian ini adalah metode campuran antara kualitatif dan kuantitatif. Populasi dalam penelitian ini adalah seluruh mahasiswa calon guru di Kota Cimahi dan sampelnya adalah mahasiswa calon guru tingkat dua di STKIP Siliwangi Cimahi. Instrumen yang digunakan dalam penelitian ini berbentuk tes uraian koneksi dan komunikasi matematis, serta angket self-efficacy. Berdasarkan analisis data didapatkan kesimpulan bahwa peningkatan kemampuan komunikasi dan koneksi matematis mahasiswa calon guru yang belajar menggunakan pendekatan konstruktivisme dengan model pembelajaran generatif lebih baik dibandingkan dengan mahasiswa yang belajar dengan pembelajaran biasa, serta tidak terdapat hubungan antara kemampuan komunikasi dan koneksi matematis mahasiswa calon guru dengan self-efficacy mahasiswa calon guru.
PENERAPAN METODE PELATIHAN KARYA TULIS ILMIAHUNTUK MENINGKATKAN KEMAMPUAN GURU DALAM MENYUSUNPENELITIAN TINDAKAN KELAS (Penelitian Tindakan terhadap Guru-guru SDdi Kota Cimahi Semester 1 Tahun 2016/2017)
Authors: Muslihuddin Muslihuddin
Published: April 2019

Fakta empirik dilapangan ternyata banyak ditemukan lemahnya kompetensi profesional, yaitu kemampuan menulis karya ilmiah dikalangan guru/konselor masih kurang. Bertolak dari permasalahan tersebut di atas, maka widyaiswara perlu memberikan bantuan dalam  usaha peningkatan sumber daya guru. Untuk itu widyaswaramelakukan perbaikan pembinaan melalui PTS , karena PTS merupakan cara yang tepat bagi widyaswara untuk mengatasi permasalahan guru-guru yang menjadi binaannya. Metode penelitaian yang dipilih adalah metode penelitian tindakan dalam hal ini adalah penelitian tindakan sekolah. Penelitian Tindakan Sekolah ini dilaksanakan pada guru-guru yang menjadi binaan peneliti di Kota Cimahi. Adapun tujuan dari penelitian ini adalah untuk mengetahui kemampuan guru dalam menyusun  PTK dengan  menggunakan   metode Pelatihan KTI. Berdasarkan hasil penelitian diperoleh bahwa data siklus I dan siklus II setelah diterapkan metode pelatihan PTK ternyata dapat meningkatkan kemampuan guru dalam menulis PTK.Pada Pra PTS  rata-rata nilai  37.2 dengan rincian kategori cukup 24% , kurang 60% dan sangat kurang 16%. Sedangkan pada Siklus I rata-rata nilai  55.92, dengan rincian kategori baik  28% dan kategori cukup 72%. Pada Siklus II terjadi peningkatan nilai rata-rata menjadi 76.20 dengan rincian kategori sangat baik 40% dan kategori baik 60%. Berdasarkan hasil tersebut diperoleh kesimpulan bahwa pelatihan KTI memberikan dampak yang signifikan bagi guru-guru untuk meningkatkan kemampuan menulisnya.
APPLICATION OF INVENTORY METHOD IN IMPROVING STUDENT LEARNING ACTIVITIES ON NATURAL RESOURCES SUMMARY AND ENVIRONMENTAL ENVIRONMENT
Authors: Dewi Aqmarina
Published: April 2019

The main issues of this research are how to improve the learning activity of Elementary School students on Natural Resources (NR) and Environment (EN) subject matter through the method of discovery. The objectives of the research are as follows: (1). Increase the learning activity of elementary students through discovery method; (2). Provides learning through discovery methods that enhance learning activities. The methods / approaches used in achieving the following objectives: (a). Collect students and elementary teachers involved in research; (B). Provide an overview of the research activities to be undertaken; (C). Reflecting on, discussion of learning by method of discovery; (D). Collaborate with elementary teachers in the determination of experimental class and control class; (E). Implementation of learning method of discovery; (F). Evaluation of learning by method of discovery. The results showed that there was an increase in learning activity of elementary school students through learning by inventory method of 34%; (2). Elementary students are enthusiastic about learning by the method of discovery given by the teacher; (3). The occurrence of collaboration between one student and another student at the time of learning by the method of discovery is done. Keywords: Learning Activity, Discovery Method.
Evaluating Risk and Processing Integrity Controls over Spreadsheets: An Educational Case
Authors: Bagley Penelope L. , Barnes Beau Grant , Harp Nancy L.
Published: April 2019

This case requires students to create a spreadsheet inventory, assess the risk related to each spreadsheet inventoried, and perform internal control testing on the spreadsheet deemed to be of the highest risk. Completing the case will benefit students in many ways. First, the case will familiarize students with creating a spreadsheet inventory. Second, it will familiarize students with the risks associated with spreadsheet errors by requiring them to evaluate and consider such risks. Third, the case will provide students with practice in evaluating spreadsheet controls and detecting spreadsheet errors. Finally, the case will increase students' awareness of the pervasiveness and potentially negative impact that spreadsheet errors can have on financial reporting.
“Alexa, Write an Audit Opinion”: Adopting Intelligent Virtual Assistants in Accounting Workplaces
Authors: Burns Mary B. , Igou Amy
Published: April 2019

In recent years, there has been exponential growth in the volume of “always listening” intelligent virtual assistant devices used in the home. The adoption of intelligent virtual assistants is also moving rapidly into applications and devices utilized by businesses, including accounting workplaces. Although there are highly publicized drawbacks related to the home-use of this technology, the benefits of this spoken interface are many. Therefore, it is important to review the relevant literature, such as Altman's (1975) regulation of interpersonal barriers, Nissenbaum's (2010) notions of contextual integrity, the privacy paradox (Norberg et al. 2007), and Eyal's (2014) work on habit-forming products, to help understand the concerns related to the adoption of these assistants. This paper will discuss the advantages and disadvantages of these interfaces, imagine how accountants might use these devices in the near future, examine the challenges of adopting digital assistants, and provide recommendations for future research.
Disposition of an Interest in a U.S. Partnership by a Foreign Person: The Saga of Revenue Ruling 91-32
Authors: Brajcich Andrew M.
Published: April 2019

Rev. Rul. 91-32 treats the sale of a partnership interest by a foreign partner under the aggregate approach. Gain or loss is determined by the distributive share of gain or loss arising from a hypothetical sale of the partnership's assets. To the extent gain is attributable to assets that are effectively connected to a U.S. trade or business, they are U.S. source and subject to U.S. tax. In 2017, the Tax Court declined to apply Rev. Rul. 91-32 applying the entity approach instead. Under this approach, the foreign partner has no U.S. source income from the sale of her partnership interest and is not subject to U.S. tax on any gain. Congress responded by codifying the aggregate approach in the Tax Cuts and Jobs Act. This paper looks at the history of taxing partnership sales by foreign persons and provides analysis on the state of the current law.

JEL Classifications: B17; F23; M16; H25.