bluuebunny/crossref_metadata_2025 huggingface dataset:
Development Of Mass Spectrometric Methods For The Analysis Of Serotonin And Related Compounds In Biological Matrices
Authors:   ,   Cork Institute of Technology, Moriarty Merisa
Published: September 2024

"Serotonin is a major neurotransmitter in the brain and affects various functions both in the brain and in the rest of the body. It has been linked to depression, migraines, and aggression, as well as many psychiatric disorders including schizophrenia, dementia and anorexia nervosa. It also has been associated with conditions like Alzheimer’s disease along with other neurotransmitters such as dopamine. The aim of this research project is to develop various mass spectrometric methods for the analysis of serotonin, dopamine and similar indoles in both urine and serum matrices. This thesis provides extensive reviews detailing a general overview of serotonin and related compounds, an introduction to mass spectrometry theory and the instruments used in the experimental section of this work, as well as an extensive review on the topic of ion suppression in mass spectrometry. Ion suppression is an important area of method development when dealing with complex samples such as biological matrices and can often be overlooked in tb early stages of method optimisation. This thesis presents a fully validated LC-MS/MS method and sample preparation methods for the analysis of serotonin, hydroxyindole acetic acid and dopamine in urine and serum. An extensive study into the effect of ion suppression from the various matrices was also carried out for this method. The fourth chapter details a preliminary clinical study investigating the use of serotonin, dopamine or hydroxyindole acetic acid as a biomarker for the diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) in children aged between 6-18 years. The fifth chapter presents a LC-MS/MS method for serotonin, dopamine and melatonin in serum using HybridSPE-Precipitation cartridges for sample clean-up. The final two chapters present two high mass accuracy methods using a LTQ Orbitrap mass spectrometer. These methods use different techniques for sample introduction, one being a liquid chromatographic method for separation of analytes and the other being a direct infusion method using nano-electrospray. The methods provide a novel approach to the analysis of serotonin md related compounds."
Dynamic Herbal Monographs For A Digital World
Authors:   ,   Cork Institute of Technology, O'Brien Niamh
Published: September 2024

Post analysis of a worldwide survey of Medical Herbalists, 93% of respondents were in favour of an online system which could update monographs dynamically. 63% of respondents suggested that some current monographs are out of date and lack certain practicalities in areas such as : Interactions, Dosage and Safety. Research into gaining optimal responses from surveys led to a 78% response rate. Survey analysis resulted in a modem up-to-date monograph template being created and each of the aforementioned information systems tested against same. Testing involved the generation of XML, HTML, PHP and OWL languages for encoding documents to allow for update. As a result of the implementation testing findings suggested that two of these information systems would not be compatible with dynamic updating however the results of implementation of one system is already showing positive results. This system would be run by and for the herbal community. The idea of updating herbal monographs dynamically, although, in its embryonic stage is already becoming a reality, infrastructure is in place and membership of the community who shall run this site has begun. In time it is hoped information content will become as respected as ESCOP or EMA monographs as the information is inputted by herbalists. In the field of Herbal Medicine, WikiHerb could become as important as MIMS is to the field of Conventional Medicine in this digital world.
UNA REVISIÓN COMPLETA DEL DIVERTÍCULO DE MECKEL. PRESENTACIÓN CLÍNICA, ENFOQUES DIAGNÓSTICOS Y TRATAMIENTO QUIRÚRGICO.
Authors: Angelica Estefania Chamorro Barona , Luis Alberto Yungán Guamán , Nathalia Stefania Bolaños Cruz , Natalia Isabel Morales Domínguez , Sandra Elizabeth Carmona Mendía , Carlos Andrés Muñoz Armijos , Janneth Elizabeth Palma Calles
Published: September 2024

El divertículo de Meckel, una anomalía congénita resultante de la obliteración incompleta del conducto onfalomesentérico, a menudo se pasa por alto, pero tiene una relevancia clínica significativa debido a su presentación variada y sus posibles complicaciones. Las implicaciones de un divertículo de Meckel no diagnosticado o no tratado pueden ser graves, incluido el riesgo de perforación y peritonitis posterior, lo que subraya la necesidad de un diagnóstico y una intervención oportunos. El tratamiento quirúrgico sigue siendo la opción de manejo definitivo para los casos sintomáticos, con indicaciones que van desde diverticulitis sintomática hasta complicaciones que requieren resección. Varias técnicas quirúrgicas, incluidos los abordajes laparoscópicos y abiertos, presentan diferentes resultados y complicaciones postoperatorias, lo que requiere una cuidadosa consideración por parte de los médicos en el tratamiento de los pacientes afectados.
Fungal diseases of conifers in the dendrological garden named after S.F. Kharitonov (Pereslavl-Zalessky)
Authors: Шишкина А.А. , Куликова О.Н. , Шишкина А.А.
Published: September 2024

В данной работе приведено описание грибных болезней, оказывающих негативное влияние на фитосанитарное состояние хвойных пород, произрастающих в дендрологическом саду имени С.Ф. Харитонова города Переславль-Залесский Ярославской области. Обследованы посадки интродуцированных видов – сосны черной (Pinus nigra J.F. Arnold), сосны кедровой сибирской (Pinus sibirica Du Tour), сосны кедровой корейской (Pinus koraiensis Siebold & Zucc.), ели колючей (Picea pungens Engelm.), ели канадской (Picea glauca (Moench) Voss), гибрида ели колючей и ели канадской (Picea pungens f. glauca × Picea glauca), пихты сибирской (Abies sibirica Ledeb.). Наиболее распространенными и значимыми из идентифицированных болезней являются: побеговый рак (склеродерриоз) сосны черной, сосны кедровой сибирской и сосны кедровой корейской (возбудитель – Brunchorstia pinea (P. Karst.) Höhn.); красная пятнистость (дотистромоз) хвои сосны черной и сосны кедровой сибирской (возбудитель – Dothistroma septosporum (Dorog.) Morelet); побурение хвои (ризосфериоз) ели колючей (возбудитель – Rhizosphaera kalkoffii Bub.) и пихты сибирской (возбудитель – Rhizosphaera pini (Corda) Maubl.); почернение и отмирание почек (мегалосепториоз) ели колючей, ели канадской и гибрида ели колючей и ели канадской (возбудитель – Megaloseptoria mirabilis Naumov).

This paper provides a description of fungal diseases that have a negative impact on the phytosanitary state of conifers growing in the dendrological garden named after S.F. Kharitonov city of Pereslavl-Zalessky, Yaroslavl region. Plantings of introduced species – black pine (Pinus nigra J.F. Arnold), Siberian stone pine (Pinus sibirica Du Tour), Korean stone pine (Pinus koraiensis Siebold & Zucc.), prickly spruce (Picea pungens Engelm.), Canadian spruce (Picea glauca) (Moench) Voss), a hybrid of prickly spruce and Canadian spruce (Picea pungens f. glauca × Picea glauca), Siberian fir (Abies sibirica Ledeb.). The most common and significant of the identified diseases are: shoot cancer (scleroderriosis) of black pine, Siberian stone pine and Korean stone pine (causative agent - Brunchorstia pinea (P. Karst.) Höhn.); red spotting (dotistromosis) of needles of black pine and Siberian cedar pine (causative agent - Dothistroma septosporum (Dorog.) Morelet); browning of needles (rhizospheriosis) of prickly spruce (pathogen - Rhizosphaera kalkoffii Bub.) and Siberian fir (pathogen - Rhizosphaera pini (Corda) Maubl.); blackening and dying off of the buds (megaloseptoria) of prickly spruce, Canadian spruce and a hybrid of prickly spruce and Canadian spruce (pathogen - Megaloseptoria mirabilis Naumov).
English Educational Game Modeling Using Goal Directed Design Method
Authors: Lupita Maria , Ambarwati Theresia
Published: September 2024

Language and Communication Development. Through play, children engage in conversation, listen to stories, and communicate with others. This enriches their vocabulary and helps them understand the structure of language. Early literacy is essential to early childhood learning. Playing with letters, words, and picture books helps children develop early literacy skills that are essential for later academic success. A learning aid in the media is an educational game. In this study, we developed an English vocabulary learning application for fruit and animal names. The application is used by kids between the ages of 4 and 6. The goal of this research is to create an application that will help kids recall things better and expand their vocabulary. We employ the Goal Directed Design Method for the design of the user interface. The research, modelling, requirements, definition, framework definition, refinement, and support are the eight primary stages of this method. Eighteen youngsters between the ages of four and six participated in this study. According to the application's evaluation, all participants were able to recall fruit and animal names with an approximate 10% increase.
Gambaran Fungsi Ginjal Pasien PJK dengan Oklusi Total Kronik yang Menjalani IKP di RSUP Prof. Dr. R. D. Kandou Manado Periode Januari-Desember 2022
Authors: Anjani Ni Made , Panda Agnes L. , Jim Edmond L.
Published: September 2024

Abstract: Accumulation of fat on the walls of blood vessels can affect blood flow to the heart muscles which has an impact on heart and kidney functions. This study aimed to obtain the description of kidney function in patients with coronary artery disease (CAD) with chronic total occlusion (CTO) who underwent percutaneous coronary intervention (PCI). This was a retrospective and descriptive study with a cross-sectional design. Samples were CAD patients with CTO registered in medical records of Prof. Dr. R. D. Kandou Hospital from January to December 2022. The results showed that there were 95 cases of CTO who underwent PCI. There were 36 (37.9%) patients with increased creatinine levels and decreased eGFR including 33 (34.7%) males, 20 (43.5%) aged 45-59 years, seven (7.4%) with hypertension. There were six patients (16.7%) with contrast induced nephropathy (CIN) including five (13.9%) males, three (8.3%) aged ≥70 years, and two (5.6%) with dyslipidemia. In conclusion, elevated creatinine levels and decreased eGFR are more common in males, pre-elderly, and with hypertension, meanwhile contrast induced nephropathy is more common in males, high-risk elderly, and with dyslipidemia as comorbid.
Keywords: kidney function; coronary heart disease; chronic total occlusion; percutaneous coronary intervention
 
Abstrak: Penumpukan lemak pada dinding pembuluh darah dapat memengaruhi aliran darah ke otot jantung yang berdampak pada fungsi jantung dan ginjal. Penelitian ini bertujuan untuk mengetahui gambaran fungsi ginjal pasien penyakit jantung coroner (PJK) dengan oklusi total kronik (OTK) yang menjalani intervensi koroner perkutan (IKP). Jenis penelitian ialah deskriptif retrospektif dengan desain potong lintang. Sampel penelitian ialah pasien PJK dengan OTK yang tercatat di Rekam Medik RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Desember 2022. Hasil penelitian mendapatkan 95 kasus OTK yang menjalani IKP. Terdapat 36 (37,9%) mengalami peningkatan kadar kreatinin dan penurunan eGFR di antaranya 33 (34,7%) laki-laki, 20 (43,5%) berusia 45-59 tahun, tujuh (7,4%) dengan hipertensi. Terdapat enam pasien (16,7%) yang mengalami contrast induced nephropathy (CIN) diantaranya lima (13,9%) laki-laki, tiga (8,3%) berusia ≥70 tahun, dan dua (5,6%) dengan dislipidemia. Simpulan penelitian ini ialah peningkatan kadar kreatinin dan penurunan eGFR sering terjadi pada laki-laki, kelompok pra lanjut, dengan hipertensi sedangkan contrast induced nephropathy sering terjadi pada pasien laki-laki, usia lanjut berisiko tinggi dan penyakit penyerta dislipidemia.
Kata kunci: fungsi ginjal; penyakit jantung koroner; oklusi total kronik; intervensi koroner perkutan
Prevalence of Cardiovascular Risk Factors amongst Middle-Aged Adults Attending Outpatient Clinic of Ekiti State University Teaching Hospital, Ado-Ekiti, Ekiti State, Nigeria
Authors: John Owoyemi Ayodeji , Anthony Agbesanwa Tosin , Felix Aina Olukayode , Gbenga Akinlua Damilola , Olalekan Jolayemi Temitope , Tayo Ibirongbe Adebola , Yetunde Akinola , Olayinka Oguntiloye Olabode , Adebayo Owolabi Sunday
Published: September 2024

Background: Cardiovascular diseases, including stroke, heart failure and kidney disease, have been common in sub-Saharan Africa for many years. These cardiovascular diseases have been linked to several risk factors which are classified as modifiable and non-modifiable risk factors. This study assessed the prevalence of cardiovascular risk factors amongst middle-aged adults attending the outpatient clinic of Ekiti State University Teaching Hospital (EKSUTH), Ado Ekiti, Ekiti state. Methods: A cross-sectional descriptive study of 206 middle-aged adults attending the outpatient clinic was carried out over 4 months. The respondents were selected through systematic sampling. The instrument used was a structured questionnaire. Data analysis was done using Statistical Package for service solution (SPSS) version 23. Results: The respondents were aged 40-64 years, with a mean age of 51.47±7.83. There was a high prevalence of cardiovascular risk profiles among middle-aged adults with the prevalence of dyslipidaemia and hypertension being 73.3% and 46.1% respectively. Conclusion: This study shows the high prevalence of cardiovascular risk factors in middle-aged adults. Family physicians should therefore actively seek to screen their patients for cardiovascular risks while also engaging in the education of patients on positively modifying the modifiable risk factors.
ANÁLISE DO PERFIL EPIDEMIOLÓGICO DE INTERNAÇÕES POR CÂNCER DE CÓLON NO BRASIL ENTRE 2013 E 2023
Authors: Seckim Jamilly Soares , Lorenzoni Silvia Maria Mauri , Guimarães Esther Golçalves , Boechat Letícia Barbosa André , Silveira Mariana Freire Secati , Silva Alexandrine Bremide da
Published: September 2024

INTRODUÇÃO: O câncer de cólon é um tumor localizado no intestino grosso que, assim como outros tipos de câncer, tem como fisiopatologia a produção excessiva e desordenada de células. Várias hipóteses são consideradas para explicar o aumento gradativo desse tipo de câncer e a mudança de público: indivíduos saudáveis com menos de 50 anos estão sendo cada vez mais acometidos. O câncer de colón tem variadas formas de manifestação, desde assintomático a sintomas gastrointestinais e, ao exame físico e laboratorial, os principais achados são massa abdominal palpável e anemia. METODOLOGIA: Trata-se de um estudo transversal descritivo, de abordagem quantitativa, baseado na coleta de dados presentes no departamento de informática do Sistema Único de Saúde (SIH/DATASUS), do Ministério da Saúde associado ao Departamento de Informática do Sistema Único de Saúde por meio do endereço eletrônico. RESULTADOS E DISCUSSÕES: Ao analisar o número de internações por sexo no Brasil, totalizam 383.799 internações, com predomínio no sexo feminino, com 50,81% dos casos. Com relação ao número de internações por idade, com um total de 383.799 internações, o estudo demonstrou maior prevalência de casos entre a faixa etária de 60 a 69 anos.CONSIDERAÇÕES FINAIS: A partir dessa análise, pode-se afirmar que a região Sudeste é a mais significativa quanto aos casos notificados de câncer de cólon e que o maior acometimento é entre 60 e 69 anos e no sexo feminino. Evidencia-se o aumento da frequência desta patologia em todo o país, o que demonstra a necessidade de um rastreamento precoce e eficaz além da adoção de medidas que estimulem sua prevenção.
PIPPALIMULADI AGADA-A REVIEW
Authors: Dr. Akbersha.A  , Dr. Ashwin Kumar S Bharathi  , Dr. Rajath.M
Published: September 2024

Background- Agadatantra is included under Ashtangas that not only deals with diagnosis of poisons bites and stings but also deals with different types of toxicity such as concotent (Gara Visha) and Cumulitive toxicity (Dushi Visha ) .Dushi Visha is one among the widely discussed topics in Agadatantra. All the brihatayess and in Malayalam text books deals this topic detailly. Many Agada Yogas are described by acharyas for managing Dooshi visha .
Introduction- Pippalimuladi agada is one of the Agada Yoga detailed in the book Kriyakoumudi in relation to dushi visha. Kriyakoumudi is one of the classic literature accessible for Agadatantra. This book focuses exclusively on different types of poisons and their traditional treatments. We discovered various Agada Yogas in this book that Brihatrayees did not address.
Objective
1.To study the pharmacological and therapeutic action of pippalimuladi agada.
2. To study the pharmacological and therapeutic action of each ingredient of pippalimuladi agada.
Materials and methods- The whole study is based on literary review collected from AyurvedSamhitas and Kriyakoumudi.
Conclusion-The components in pippalimuladi agada have anti-inflammatory, antifungal, antimicrobial, antioxidant, and diuretic properties. This review article will discuss the pharmacological and therapeutic effects of pippalimuladi agada, as well as the effects of each ingredient.
KEYWORD: pippalimuladi agada, Kriyakoumudi, Dooshi Visha
ANALISIS KESULITAN BELAJAR SISWA DALAM MEMPELAJARI MATERI ALJABAR DITINJAU DARI GAYA BELAJAR TINGKAT SMA KELAS XI
Authors: Ni Kadek Anik Dwijayanti  , I Putu Ade Andre Payadnya  , I Gusti Ayu Putu Arya Wulandari
Published: September 2024

Penelitian ini merupakan penelitian deskriptif kualitatif yang bertujuan untuk mengetahui jenis kesulitan belajar dan faktor penyebab kesulitan belajar siswa dalam mempelajari materi aljabar ditinjau dari gaya belajar. Subjek penelitian ini yaitu siswa kelas XI B3 SMA Negeri 1 Mengwi sejumlah 30 orang siswa. Metode pengumpulan data yang digunakan adalah pemberian angket atau kuesioner, soal tes, dan wawancara. Instrumen yang digunakan adalah lembar angket atau kuesioner dan lembar soal tes aljabar. Hasil penelitian ini menunjukkan bahwa terdapat 30% siswa dengan gaya belajar visual, 13% siswa dengan gaya belajar auditorial, dan 57% siswa dengan gaya belajar kinestetik. Kesulitan yang dialami oleh siswa dalam menyelesaikan persoalan aljabar yang berkaitan dengan konsep dan prinsip adalah (1) dalam penguasaan konsep, beberapa siswa masih mengalami kesulitan dalam menentukan variabel, konstanta, dan suku-suku sejenis maupun tidak sejenis dengan persentase 9% dan 10%; (2) dalam penguasaan prinsip, banyak siswa masih mengalami kesulitan dalam membagi suatu pecahan dengan pecahan bentuk aljabar dengan persentase 56%. Adapun faktor yang menyebabkan kesulitan belajar siswa dalam mempelajari materi aljabar adalah faktor intern dan faktor ekstern. Faktor intern berupa minat, motivasi, bakat, dan intelegensi yang dimiliki oleh siswa, dan faktor ekstern berupa penggunaan alat peraga oleh guru dan letak gedung sekolah.
PRINCIPLES OF ESG CONCEPT AS A BASIS FOR COMPETITIVE AND EFFECTIVE STRATEGY OF INDUSTRIAL ENTERPRISES DEVELOPMENT
Authors:   Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia, Izmaylov Maxim K.
Published: September 2024

The research is devoted to the study of the integration of ESG concept principles (environmental, social and managerial) into the strategic management of industrial enterprises as a basis for ensuring their longterm competitiveness and performance efficiency. The paper comprehensively analyzes the approaches to ESGtransformation of industrial companies, reveals both general regularities and specific features of this process. The general regularities include: the need for comprehensive ESG-diagnostics of the initial state of the enterprise, the importance of integrating ESG-targets into the general system of strategic management, the importance of involving all departments and levels of management, as well as the expediency of using a step-by-step approach to ESG-transformation. Specific features are associated with the need to adapt ESG practices to the industry specifics and national-cultural features of the regions where industrial enterprises operate, as well as with differences in the mechanisms of integration of ESG objectives into the overall management system. Based on the analysis, a conceptual model of ESG-principles integration into the strategic management of industrial enterprises has been developed. This model includes key elements: comprehensive ESG-diagnostics, formation of strategic ESG-initiatives, consistent transformation of business processes, involvement of all levels of management, as well as adaptation to industry and regional specifics. In addition, econometric models are built in the paper to assess the impact of the integral ESG index, as well as its individual components (environmental, social and managerial) on the indicators of competitiveness (market share) and performance efficiency (return on assets) of industrial enterprises. The obtained results can serve as a basis for the development of reasonable recommendations on priority directions of ESG-transformation. The conducted research demonstrates that the principles of ESG concept should be considered by industrial companies as a key element of competitive and effective development strategy ensuring their long-term sustainability. The integration of ESG factors into strategic management becomes an important factor in improving the competitiveness and efficiency of industrial sector enterprises in modern conditions.
En los márgenes de la filosofía enmohecida
Authors: Borsani María Eugenia
Published: September 2024

Este trabajo muestra cómo Mariflor Aguilar Rivero sacude la filosofía de todo enmohecimiento. Ha sabido irse a los márgenes, a moverse críticamente respecto a la filosofía canónica, virando hacia esos bordes en donde la filosofía hoy hace falta, en donde se vuelve necesario la acción filosófica de cara al mundo y sus urgencias, de cara a la aflicción del presente. Es inestimable la prestación de la filosofía que, conmovida ante el dolor mundano y en pos de generar algún tipo de torsión, posibilite pensar el hoy en otra clave. Eso hace Mariflor Aguilar Rivero al ponernos frente a sus análisis más recientes respecto al “estado de exterminio”, como denomina al ordenamiento político propio de nuestras democracias liberales, en el que habitamos en tanto sujetos chatarras, desechables y agrego, existencias fútiles tanto como aniquilables, extinguibles, subsumidas en y subyugadas por la tramposa narrativa de la ciudadanía.
El aparato mayestático
Authors: Vázquez Guillermo
Published: September 2024

Desde las conmemoraciones más institucionales hasta una amplia gama de trabajos académicos sobre su actualidad, la idea de autonomía universitaria ha sido vinculada a la gesta histórica cordobesa: la Reforma de 1918 (y viceversa). Cierto es que tangencialmente alguno de los congresos de estudiantes nucleados en el proceso reformista señaló como uno de los ejes de discusión la necesidad de defensa de la autonomía universitaria, así como también en otras latitudes del continente el tema era bien distinto a la realidad cordobesa, y sí se incorporó con más fuerza dicho concepto como parte del ideario reformista. Sin embargo, un recorrido por el primer proceso del 18 nos revela la casi nula relevancia (cuando no la total ausencia) de la idea de autonomía entre sus reivindicaciones más propias: atendiendo a sus documentos (como “La Gaceta Universitaria”, periódico de los estudiantes reformistas), actas de los encuentros más relevantes (congresos de estudiantes, mítines políticos), discursos y textos de sus principales figuras y referentes. Pero es sobre todo en la propia dinámica legal y política del acontecimiento del 18 (intervenciones del Poder Ejecutivo, la Ley Avellaneda, proyectos de reforma), y en su  cabal comprensión, que encontramos la mayor dificultad para señalar la autonomía entre los principios que fundaban las acciones de los reformistas, como tampoco entre sus demandas más persistentes –cogobierno, libertad de cátedra, compromiso social de la universidad, nueva ley de educación superior, derechos estudiantiles  básicos, etc. Será recién en los años 30, cuando la contrarreforma en marcha provenía desde un Poder Ejecutivo reaccionario y hasta filo fascista. Posteriormente, con la llegada del peronismo al poder, la discusión será otra, pero es menester precisar que en esa misma época un conjunto de referentes y de agrupaciones vinculadas al acontecimiento del 18 –o reivindicando su legado–, instalaron la idea de autonomía como conflicto permanente entre el Estado y la universidad 1 , como reflejo innegable de la lucha que forjó al movimiento estudiantil décadas atrás.
World Heritage Cities in the context of urban renewal: The reuse pathway of heritage buildings in Suzhou, China
Authors: Chen Xi , Shi Qinyi , Pan Yiting
Published: September 2024

Suzhou in China, as a participant in UNESCO’s World Heritage Cities Program, stands as one of China’s pilot cities for urban renewal. Within its historic urban areas, the city has implemented innovative practices and strategies to revitalize its tangible and intangible heritage. This paper delves into the crucial issue of heritage building reuse, aiming to strike a balance between their “specimen” and “living” values. To define the success of reuse projects, this study compares evaluation criteria and parameters from both domestic and international contexts. The paper then focuses on examining the exemplary reuse practices in Suzhou, leading to the identification and summarization of the “Suzhou reuse pathway.” Specifically, value construction serves as a case study to assess the impact of heritage reuse through the analysis of public feedback. This examination underscores the effectiveness of Suzhou’s pathway, positioning it as a positive reference in the global discourse on architectural heritage conservation and sustainable development in World Heritage Cities.
Populist Politics in India: Comparing Indira Gandhi with Narendra Modi
Authors: - Shreya Tiwari
Published: September 2024

This research report explorers the phenomenon of populism in India, with the particular focus on the two prominent populist leaders, Indira Gandhi and Narendra Damodar Das Modi. The report aims to define and contextualise populism within the Indian context, by comparing the populist approach of, Modi and Gandhi, and by also evaluating their respective impact on the political system of India. Populism, characterised by its appeal to the common appeal against the elite and its use of charismatic leadership, has significantly shaped India’s political
landscape.
Pattern of Comorbid Substance Abuse in Patients of Depression
Authors: - Muskan Verma , - Mahewash Hasan , - Nishi Tripathi
Published: September 2024

This study explores the comorbidity of substance abuse among patients attending a Psychiatric Outpatient Department. The research focused on a sample of 100 individuals diagnosed with depression, drawn from four different clinics within the Muzaffarnagar District. The sample was evenly divided, with 50 respondents experiencing substance abuse and 50 without any history of substance abuse.
To assess the severity of depression, the Hamilton Depression Rating Scale (HDRS)—also known as the Hamilton Depression Scale (HDS) or simply the Hamilton Scale—was employed. This scale, developed by Dr. Max Hamilton in 1960, is a widely recognized instrument for evaluating the intensity of depressive symptoms and is extensively used in both clinical and research contexts.
For the screening of substance abuse, the World Health Organization's Alcohol, Smoking, and Substance Involvement Screening Test (WHO ASSIST) questionnaire was utilized. This tool, developed by WHO, is designed to detect substance use and associated problems.
The findings of the study are :
• There were three types of comorbid Substance Abuse in patients of Depression and those are Alcohol , Tobacco and Cannabis
• Respondents with Substance Abuse have more severe depression than respondents without Substance Abuse
• And these findings are presented with frequency and percentages, and they are supported by relevant research.
The Influence of Bullying on the Level of Anxiety in Youth
Authors: - Divi Saini
Published: September 2024

The present study explores the connection between bullying and anxiety among university students aged 18 to 22. Utilizing a convenience sample of one hundred students, the intensity of bullying and anxiety levels were measured using the Perception of Teasing Scale (POTS) and the Hamilton Anxiety Rating Scale (HAM-A), respectively. Using correlation and regression analyses to decipher the data, it was discovered that bullying significantly predicts anxiety among this demographic. Notably, the study also revealed that female university students experience higher levels of anxiety related to bullying compared to their male counterparts. Further research is recommended to explore interventions and strategies to counteract bullying and its associated anxiety within university settings.
Vascularités de causes infectieuses du système nerveux central
Authors: De Broucker Thomas , Henry Carole
Published: September 2024

Les maladies infectieuses touchant le système nerveux peuvent fréquemment se compliquer d’atteintes vasculaires intracrâniennes. Leurs conséquences ischémiques ou hémorragiques parenchymateuses cérébrales sont la cause de séquelles durables qui font un des aspects de la gravité de la maladie infectieuse causale. La revue actualisée de la littérature permet de décrire les spécificités diagnostiques et éventuellement thérapeutiques des affections bactériennes, virales, fungiques, et parasitaires à l’origine de ces complications vasculaires.
Physicochemical Properties of Morinda Citrifolia Fruits and Leaves Produced by Oven and Freeze Drying
Authors: Wan Syazana Auni Binti Zawawi  , Yusof Norzaida , Yusof Nurhayati , Mat Gani Hanis Syazwani
Published: September 2024

Morinda citrifolia, also known as Noni, is a nutritional plant that contains beneficial characteristics and has been explored in both the pharmaceutical and food industrial fields. This study was carried out to compare the physicochemical properties of Noni fruits and leaves powder produced by freeze-drying and oven drying methods. Oven drying was carried out at different temperatures (50 °C, 60 °C, and 70 °C) while the freeze-drying method was carried out at constant temperature (-50 °C) and time (40 hours). The physicochemical properties (antioxidant, moisture content, water activity, density, water solubility, and color) of the fruits and leaves powder were analyzed. Freeze-drying produced the lowest moisture content and water activity of Noni fruit and leaf powder. The study revealed that increased in oven drying temperature decreased the color properties (L*, a*, b*), moisture content and water solubility of both Noni fruit and leaves powder. Bulk and tapped density showed slightly changes with an increase in drying temperature. Oven dried Noni fruit and leaf powder at 50 °C had the highest percentage of DPPH radical scavenging activity. Besides, freeze-drying proved to have better physicochemical properties in Noni fruits and leaves. The results obtained indicate a significant difference between the physicochemical properties of freeze dried Noni fruits and leaves powder in terms of water activity, color, and DPPH radical scavenging activity.
Maturity Assessment Based on Physicochemical Properties of Senna tora Compost Production Using Bokashi Technique
Authors: Yusop Mohamad Amir Shah , Ismail Zaidi , Mohammed Anisah , Hendrie Johann Muhamad Ridzwan  , Badli Esham Ahmad
Published: September 2024

Senna tora is a leguminous plant species belonging to the Fabaceae family, known for its ability to engage in nitrogen fixation. It might improve compost output for sustainable soil fertility control. Bokashi compost is an organic amendment produced in two to four weeks through the fermentation of organic material. The purpose of this study is to assess the maturity of Senna tora compost made using the bokashi method for future uses. Senna tora compost produced by the bokashi method reached a mesophilic temperature (> 35 °C) on the first day and a thermophilic level (> 50 °C) on the second day. From Day 2 to Day 12, a thermophilic temperature level was observed. The temperature decreases until Day 35, signifying the finish of the decomposition process. The pH level of the compost showed a fluctuating pattern, starting at 7.8 and spiking at 8.4 before lowering to 7.2 (neutral) by the end of the study. The height of the compost decreased by approximately 53.97% over the duration of the study, showing that the decomposition process has reached a state of maturity. During the decomposition process of Senna tora, the nutrients nitrogen (N), phosphorus (P), and potassium (K), with 2.88%, 0.654% and 6.671%, respectively, are released and eventually reach the desired target value. The initial carbon-to-nitrogen (C/N) ratio of the compost was 25, and it gradually decreased to 14 at the end of study. Senna tora compost produced a statistically significant result in the evaluation of compost maturity. The compost is deemed suitable for use as an organic fertilizer since it meets the specified nutrient availability criteria.
Efektivitas Media Kartun terhadap Hasil Belajar Siswa pada Pembelajaran Tematik Kelas II
Authors: Imroatul Mufidah  , Sri Hartatik  , Nafiah Nafiah  , Pance Mariati
Published: September 2024

Increasing educational qualifications is necessary for good knowledge, being able to convey and having an attitude of exemplary students, students of skills acquired holistically can be useful in the world of education. The role of the teacher is to make the most of learning materials and media. Learning media is used to make students interested in participating in learning and it is hoped that learning can be carried out effectively. The research aims to find out how effective cartoon media is on student learning outcomes in class II thematic learning at SD Mabadiul Ulum Surabaya using the One Group Pretset- Posttest method. In this study the aim was to find out student learning outcomes after applying cartoon media. This research was carried out on May 15, 2023. Data collection techniques used tests in the form of pretest and posttest. The results of this study indicate that there are differences in student learning outcomes before and after the application of cartoon media with an average increase of 78,667 which can be said that cartoon media is effective for use in class II thematic learning at SD Mabadiul Ulum Surabaya. Because the value is more than 0.76%.
POSSIBLE WAYS OF DIGITAL DEVELOPMENT OF THE SPORTS INDUSTRY IN THE REPUBLIC OF NICARAGUA USING THE AUTOMATED INFORMATION SYSTEM “MY SPORT”
Authors: Markov Andrey Sergeevich , Grigorieva Irina Igorevna , Potapov Fedor Sergeevich
Published: September 2024

The work identified and described the main features of the work in the “Digital Athlete Profile” functional block developed for implementation both on the territory of the Russian Federation and abroad, taking into account the peculiarities of public administration in the field of physical culture and sports of the Republic of Nicaragua.
Análisis de las Percepciones y Conocimientos sobre la Educación Inclusiva de los Estudiantes de últimos Semestres de Licenciaturas de la Universidad del Tolima
Authors: Amador Pineda Luis Hernando , Ramírez Suarez Gimena Rocío , Bedoya Valderrama Luna Daniela , Sánchez Castañeda Windy Solenyi
Published: September 2024

El documento examina cómo los futuros educadores perciben y entienden la educación inclusiva en el contexto de la Universidad del Tolima. A pesar de la creciente importancia de la inclusión educativa, se evidencia una falta de conocimiento sobre políticas y prácticas inclusivas, con un enfoque limitado principalmente en la discapacidad, mientras que otros aspectos de la diversidad son menos considerados. El estudio destaca que muchos estudiantes provienen de contextos de riesgo de exclusión social, lo que subraya la necesidad de una formación más integral en estos temas. Se concluye que es esencial fortalecer la preparación de los futuros maestros para promover aulas más inclusivas y equitativas, abordando las diversas dimensiones de la inclusión en la educación.
Aula Invertida, Revisión Sistemática y Prospectiva en el Contexto de la Educación Física
Authors: Castro Campos Pedro Alfonso , Vargas Silva Flor Alba
Published: September 2024

Los avances en las TIC han configurado cambios significativos y de gran trascendencia en el contexto de la escuela actual y su ideal de formar estudiantes activos, autónomos y con pensamiento crítico frente al conocimiento, en esa perspectiva se estructuran estrategias innovadoras como el Aula Invertida. En tal sentido, el presente estudio tiene como objetivo analizar de forma sistemática la producción bibliográfica de la metodología Aula Invertida y su implementación en el área de la Educación Física en el periodo 2017-2022. Para el abordaje metodológico se emplearon los parámetros del Framework SALSA. A partir de la búsqueda y revisión; se consideran los criterios de inclusión y exclusión, en consecuencia, quedaron 22 artículos para el análisis final. En los resultados se evidenció que el año 2021 tiene la frecuencia más alta en la elaboración de estudios, por su parte, España tiene el número más elevado de investigaciones, a su vez, el nivel de secundaria registró la mayor cantidad. En cuanto a las plataformas digitales o herramientas tecnológicas más utilizadas: videos, Edpuzzle, cuestionarios. Finalmente, se hilvanan conclusiones producto de la revisión, la mayoría de estudios afirman que la metodología tiene un efecto significativo y positivo en los niveles de motivación de los estudiantes y en consecuencia en el desarrollo de las clases, por ende, su percepción es más positiva e innovadora en comparación con las metodologías tradicionales.
The sound of silence: navigating the challenges in treating deaf psychiatric patients
Authors:   “Prof. Dr. Alexandru Obregia” Clinical Psychiatry Hospital, Bucharest, Romania, Ion Adriana , Horosan Lavinia ,   “Prof. Dr. Alexandru Obregia” Clinical Psychiatry Hospital, Bucharest, Romania, Nistor Diana-Elena ,   “Prof. Dr. Alexandru Obregia” Clinical Psychiatry Hospital, Bucharest, Romania, Giurgiuca Ana ,   “Prof. Dr. Alexandru Obregia” Clinical Psychiatry Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: September 2024

This case report illustrates the challenges of assessing mental health in a patient with deafness and limited speech without a sign language interpreter. The discussions emphasize the critical need for sign language interpreters in healthcare, especially psychiatry, where nuanced communication is pivotal for diagnosis. The complexities of conducting mental health assessments without sign language interpreters are highlighted, advocating for ensuring healthcare facilities have skilled sign language interpreters or can guarantee their availability when needed. Providing psychiatric care for a deaf patient without a dedicated interpreter posed significant challenges, requiring innovative approaches. Improving communication with deaf patients requires allocating more time for appointments, ensuring clear visibility of the clinician’s face, and using simple language. This case serves as a call to address communication barriers in healthcare for people with disabilities.
Finite Element Analysis of a Repaired Cracked Aluminium Plate with Piezoelectric Patches under Mechanical and Thermal Loading
Authors: Abdulla Mohammed , Hrairi Meftah , Aabid Abdul , Abdullah Nur Azam
Published: September 2024

In thin plate structures, the use of piezoelectric actuators for active repairs can significantly decelerate the progression of crack damage. The prevalent mode-I fractures, wherein tension causes the opening displacement leading to failure, undermine the structural integrity required for load support. This current research endeavors to explore how piezoelectric (pzt) actuators influence the repair efficacy of fractured structures. The ANSYS software was harnessed to conduct the study, employing the finite element method. Additionally, the study delved into the repercussions of thermal heating and performed a parametric analysis to gauge their impact on the restoration efficiency of the compromised structure. The outcomes unveiled that the application of a negative electric field through the pzt actuator effectively diminishes the stress intensity factor (SIF) at the crack tip. Moreover, it was determined that thermal stresses contribute to a 57% augmentation in SIF, posing a heightened risk of structural failure. The study's deductions emphasize the desirability of utilizing a slender actuator alongside optimally adjusted adhesive thickness to attain a more pronounced reduction in SIF.
Análise exploratória do cadastro técnico federal de atividades potencialmente poluidoras e do relatório anual: aspectos técnicos e normativos
Authors: Furtado Bernardo Alves , Lopes Olandia Ferreira , Abrantes Emanuel
Published: September 2024

Este estudo consiste em uma análise exploratória do instrumento da Política Nacional do Meio Ambiente (PNMA) Cadastro Técnico Federal Ambiental de Atividades Potencialmente Poluidoras e/ou Utilizadoras de Recursos Ambientais (CTF/APP) e do Relatório de Atividades Potencialmente Poluidoras e Utilizadoras de Recursos Ambientais (RAPP), propondo recomendações técnicas e normativas. O objetivo é aprimorar aspectos do instrumento. Para isso, a pesquisa fornece informações para a tomada de decisão dos gestores públicos, fundamentando o fortalecimento do instrumento e, consequentemente, da governança pública. Além disso, subsidia o atendimento dos Objetivos de Desenvolvimento Sustentável (ODS), o Acordo de Escazú, entre outros.
Attitudes to sustainable entrepreneurship and environmental values of students: testing measurement scale and preliminary results of cross-country study
Authors: Titko Jelena , Tambovceva Tatjana , Skvarciany Viktorija , Lapinskaitė Indrė , Solesvik Marina Z. , Uzule Kristina , Faganel Armand , Jasińska-Biliczak Anna , Budanceva Jelena , Dehtjare Jevgenija , Mironova Julija
Published: September 2024

Sustainable entrepreneurship (SE) is an approach that is crucial for creating enterprises that not only generate profit but also minimize environmental impact, promote social responsibility, drive innovations, and others. Furthermore, SE is one of the instruments to achieve Sustainable Development Goals (SDGs). The goal of this study is to investigate environmental values of students and evaluate their attitudes toward social entrepreneurship. 807 respondents from different countries (mostly from Latvia, Lithuania, Poland, and Slovenia) were surveyed using the authors’ developed questionnaire. The main blocks were tested for internal consistency. Data processing was performed by means of frequency analysis, Mann-Whitney U test and correlation analysis. The results indicate the readiness of the most of respondents to reduce use of plastics. In general, the respondents are also agreeing with the statement “People should change their buying habits and way of life to solve our environmental problems”. However, only half of respondents are ready to change their own buying habits. The level of entrepreneurial intentions among students is quite low. Only 26% of the respondents were ready to start sustainable business within 5 years of graduation, even less (24%) had a sustainable business idea. The research also revealed the fact that women have a larger interest in starting a business comparing than male respondents.
Morphology and multigene phylogeny reveal four new Xylaria (Xylariales, Xylariaceae) species from karst region in China
Authors: Zeng Wenyu , Habib Kamran , Zhou Xin , Ren Yulin , Shen Xiangchun , Wang Bei , Kang Yingqian , Kang Jichuan , Li Qirui
Published: September 2024

This study presents the identification of four novelXylariaspecies, discovered in the karst region of China. The discovery was facilitated by a rigorous analysis that encompassed both morpho-anatomical features and multi-locus phylogenetics utilizing sequences from the ITS,rpb2, andTUB2 loci. The newly identified species are designated asXylaria jichuaniisp. nov.,X. nanningensissp. nov.,X. orientalissp. nov., andX. taiyangheensissp. nov.The distinction of these species from their known counterparts was verified through comparison of morphological features and phylogenetic analysis. The study further provides detailed morphological descriptions, illustrative representations, and a phylogenetic tree, all of which contribute to the taxonomic positioning of these novel species.
L'État et les stratégies du territoire
Authors: Knight David B.
Published: September 2024

L’article explore la notion de contrôle. Le terme est en quelque sorte le négatif de celui de liberté et comporte, comme elle, des degrés. Il implique la présence d’au moins deux parties. Il s’exerce dans le temps et dans l’espace et repose sur la régulation des mouvements opérée grâce à des entités territoriales que l’on surveille. Il s’appuie sur des structures politiques, sociales, économiques et militaires et met en jeu des stratégies formelles et informelles. Ceux qui sont l’objet d’un contrôle n’en ont pas toujours conscience lorsqu’il s’agit d’une domination collective imposée par le jeu de règles culturelles. Les questions que pose l’analyse du contrôle sont multiples : sur quoi repose, par exemple, l’idée que certaines personnes ont le droit de contrôler les autres ? Dans quelles conditions accepte-t-on les contraintes qu’elles cherchent à faire régner ? Quelles différences existe-t-il entre les niveaux locaux, régionaux et nationaux du contrôle politique ? Quelles stratégies les États élaborent-ils pour contrôler d’autres Etats ?
L'État et les stratégies du territoire
Authors: Groenendijk J.G.
Published: September 2024

Le contrôle de l’extension des agglomérations urbaines constitue une préoccupation majeure dans beaucoup de pays, mais la fragmentation du pouvoir politique le rend souvent difficile. L’article met l’accent sur les problèmes qui naissent de la superposition d’instances locales et d’instances provinciales ou nationales. II n’en résulte pas de dichotomie nette dans les attitudes et dans les politiques, mais une dilution des responsabilités. Les stratégies suivies cherchent à minimiser les conflits, ce qui écarte parfois de la solution optimale. Ces thèmes généraux sont illustres par des exemples néerlandais : celui des tensions municipalités/province à propos de l’industrialisation induite par l’aéroport de Schiphol, celui des transformations qui se produisent à la périphérie de quatre agglomérations moyennes, et hors de leur périmètre, et celui qui naît du choix de l’implantation de grandes surfaces dans la Randstad.
Communication scientifique et science ouverte
Authors: Prime-Claverie Camille , Poupardin Elsa
Published: September 2024

Résumé Le blogging scientifique qui se développe sur Hypotheses.org depuis 2008 n’a jamais été étudié de manière quantitative. L’analyse de 389 089 contributions réparties sur 3 540 blogs depuis la création de la plateforme a permis de cartographier les réseaux de carnetiers sur différentes périodes. L’étude des co-présences des auteurs sur les blogs a permis de mettre en évidence des interactions, jusque-là invisibles par les méthodes scientométriques traditionnelles, aussi bien entre communautés disciplinaires qu’entre différentes strates d’écriture de la recherche en SHS (individus, programmes de recherche, institutions, séminaire, etc.).