bluuebunny/crossref_metadata_2025 huggingface dataset:
Advancements in macromolecular complexity and their implications for drug delivery systems
Authors: Hamzy Ibrahim Abdullah , Alqhoson Abdulelah Ibrahim , Aljarbou Anas Mohammed , Alhajri Mohammed Abdulrahman
Published: August 2024

Background: Nanomaterials have revolutionized drug delivery systems, offering enhanced efficacy, reduced side effects, and improved patient compliance. Recent advancements in nanomedicine have focused on increasing macromolecular complexity to develop more sophisticated therapeutic options. Aim: This review explores the evolution of nanotherapeutics, from simple linear structures to complex branched and hyperbranched architectures and examines their implications for future drug delivery systems. Methods: The review discusses various nanocarriers, including liposomes, polymeric nanocarriers, and colloidal suspensions, emphasizing the role of macromolecular complexity in improving drug delivery efficacy. Key chemical techniques for synthesizing these macromolecules, such as controlled radical polymerization and click chemistry, are also analyzed. Results: Advances in synthetic polymer chemistry have enabled the development of diverse macromolecular structures that enhance drug loading, stability, and controlled release. Liposomal technology, although highly effective, faces challenges such as drug leakage and immune response, leading to the exploration of synthetic polymers like PLGA and polymeric micelles. These innovations have improved the pharmacokinetic properties of drug delivery systems. Conclusion: Increasing macromolecular complexity in drug delivery systems holds significant potential for overcoming physiological barriers, optimizing therapeutic outcomes, and fulfilling the demand for multifunctional nanomedicine.
Exploring how lifestyle choices influence the management of chronic diseases-role of healthcare providers
Authors: Alotaibi Fahdah Mehsan , Almazam Abdulrhman Ali , Alotaibi ‏Motaeb , Emam ‏Arwa Mohammad , Alqahtani ‏Naif Saad , Alheggi ‏Ashwaq Ibrahim , Alanazi ‏Ashwaq Fahad , Alharbi ‏Khlood Khaldan , Alhamed ‏Arwa Abdullah , Ali ‏Eman Ibrahim Alshaikh , Alnemer Maram Jaafar , Alghamdi ‏Mahfoudh Saad , Alomayrah ‏Norah Mubarak , Alsharari ‏Abdulaziz Shaem , Alsharari ‏Sami Farhan , Alshamari ‏Moteb Roshaid , Lamfon ‏Nahid Ahmad , Al-Qahtani Asma Saad
Published: August 2024

Background: Chronic diseases are increasingly prevalent worldwide, with lifestyle choices playing a significant role in their management. Free radicals and oxidative stress have been implicated in various chronic conditions, including cardiovascular diseases, cancer, and neurodegenerative disorders. These conditions arise from an imbalance between reactive oxygen species (ROS) production and the body's antioxidant defenses. Aim: This review aims to explore how lifestyle choices influence oxidative stress and chronic disease management, with a focus on the role of healthcare providers in guiding lifestyle modifications to mitigate oxidative stress and improve health outcomes. Methods: A comprehensive review of the literature was conducted, focusing on the mechanisms of oxidative stress and its impact on chronic diseases. Studies on the effects of lifestyle factors such as diet, exercise, smoking, and alcohol consumption on oxidative stress were analyzed. The role of antioxidants in counteracting oxidative damage and their implications for chronic disease management were also examined. Results: The review highlights that lifestyle factors significantly affect oxidative stress levels. Moderate exercise enhances antioxidant defenses, while excessive physical activity, smoking, and alcohol consumption exacerbate oxidative stress. A diet rich in antioxidants helps mitigate oxidative damage.
Anticipating future global health crises
Authors: Alotaibi Fahdah Mehsan , Almazam Abdulrhman Ali , Alotaibi ‏Motaeb , Emam ‏Arwa Mohammad , Alqahtani ‏Naif Saad , Alheggi ‏Ashwaq Ibrahim , Alharbi ‏Khlood Khaldan , Alhamed ‏Arwa Abdullah , Ali ‏Eman Ibrahim Alshaikh , Alnemer ‏Maram Jaafar , Almussa ‏Nujoud Abdulrahman , Aldosari ‏Muteb Abdullah , Alghamdi ‏Mahfoudh Saad , Alharbi Nasser Hamoud Mohammed
Published: August 2024

Introduction: Despite initial optimism about controlling infectious diseases with antibiotics and vaccines, the emergence of the HIV pandemic and recent global health crises have highlighted the persistent threat of infectious diseases. The rise of antimicrobial resistance, novel viral agents like SARS-CoV-2, and bioterrorism underscore the need for ongoing vigilance. Emerging infectious diseases are those with increasing incidence or potential for increase, often stemming from zoonotic origins due to human-animal interactions and environmental changes. Aim: This article aims to review strategies for addressing emerging infectious diseases and preparing for future pandemics, emphasizing the roles of healthcare professionals and essential preparedness measures. Methods: A comprehensive review of historical and recent data on infectious disease emergence, including zoonotic pathogens and antimicrobial resistance, was conducted. The roles of physicians, pharmacists, and nurses in managing these diseases are analyzed, along with strategies for pandemic preparedness. Results: Effective strategies include strengthening global surveillance systems, investing in research and development of vaccines and treatments, improving preparedness planning, and fostering international collaboration. Key roles of healthcare professionals include diagnosis, treatment, medication management, infection control, and patient education.
An in-depth overview of controlled drug delivery systems
Authors: Hamzy Ibrahim Abdullah , Alqhoson Abdulelah Ibrahim , Aljarbou Anas Mohammed , Alhajri Mohammed Abdulrahman
Published: August 2024

Background: Drug delivery systems (DDS) are crucial in modern medicine for optimizing the therapeutic efficacy and safety of pharmaceutical agents. Traditionally, direct use of active pharmaceutical ingredients (APIs) poses challenges such as dosing accuracy, stability, and patient compliance. Controlled drug delivery systems have emerged to address these issues by releasing drugs at a controlled rate, thereby enhancing therapeutic outcomes and minimizing side effects. Aim: This article aims to provide a comprehensive overview of current advancements and future prospects in controlled drug delivery systems. It explores various DDS technologies, their mechanisms, and their impact on drug efficacy and patient adherence. Methods: The review synthesizes data from recent research on drug delivery systems, focusing on their classification, design considerations, and performance. It discusses the pharmacokinetics of drug release, including absorption, distribution, metabolism, and excretion, and evaluates different controlled release mechanisms such as dissolution-controlled, diffusion-controlled, and osmotic pressure-controlled systems. Results: Controlled DDS have evolved significantly from the first-generation systems that relied on basic mechanisms like dissolution and diffusion to advanced technologies involving stimuli-responsive biomaterials. These systems now include innovations such as nanoparticle-based delivery, self-regulating devices, and long-term non-invasive methods for proteins and nucleic acids.
Comportamiento productivo de cerdos alimentados con suplemento fermentado en estado sólido a base de Saccharum officinarum L. y Moringa oleifera Lam
Authors: Mejía Tinoco Wendell Antonio , Reyes-Sánchez Nadir , Mendieta-Araica Bryan Gustavo
Published: August 2024

Los suplementos alimenticios como alternativas en la alimentación animal pueden ser económica y bilógicamente viable. Con el objetivo de evaluar el efecto de la suplementación con la fermentación en estado sólido de Saccharum officinarum L. y Moringa oleifera Lam. (FES-Moringa) sobre el comportamiento productivo de cerdos en engorde. Esta investigación se realizó en la Dirección Específica de Ciencia Animal de la Universidad Nacional Agraria; se utilizaron 15 cerdos con peso promedio inicial de 54.2 ± 2.8 kg distribuidos en un diseño completamente al azar con tres tratamientos y cinco repeticiones. Los tratamientos consistieron en niveles de inclusión de FES-Moringa en el concentrado comercial: El tratamiento uno fue 100 % de concentrado comercial; el tratamiento dos fue la mezcla de concentrado comercial más 15 % de FES-Moringa y el tercer tratamiento la combinación de concentrado comercial más 25 % de FES-Moringa. Las variables productivas evaluadas fueron: peso vivo final (kg), ganancia de peso total (kg), ganancia media diaria (g), conversión alimenticia (kg) y consumo de alimento (kg). El análisis estadístico se realizó mediante un análisis de varianza y comparaciones de medias usando la prueba de Tukey con 95 % de confiabilidad. En peso vivo final, ganancia de peso total, ganancia media diaria y conversión alimenticia no presentaron diferencias estadísticas entre los niveles de inclusión de FES-Moringa al 15 % y 25 %, sin embargo, son superados por el concentrado comercial, excepto para conversión alimenticia. En el caso del peso inicial y del consumo de alimento, no se presentan diferencias. La inclusión de FES-Moringa al 25 % presenta el menor costo total de alimento consumido (USD 34.23) y mayor utilidad bruta (USD 25.11).
Peran Teknologi Pertanian Cerdas (Smart Farming) untuk Generasi Pertanian Indonesia
Authors: Halawa Destri Nugrahni
Published: August 2024

Smart Farming atau pertanian digital adalah solusi pintar di sektor pertanian yang memanfaatkan sistem jaringan berbasis Internet of Things (IoT) untuk melakukan pemantauan dan pengendalian otomatis pada area pertanian. Hasil dari pertanian cerdas perlu didefinisikan dan dievaluasi agar dapat meningkatkan pemahaman petani bahwa dengan pertanian cerdas dapat menghasilkan sesuatu hal yang baru dan positif. Manfaat pertanian cerdas akan memberi perubahan yang lebih baik terhadap pendapatan sekaligus produktivitas petani, serta memperbaiki struktur kondisi sosial ekonomi khususnya petani pedesaan. Permasalahan bagi petani saat ini, untuk pengambilan keputusan yang sesuai dan tepat bagi masyarakat petani dalam pembudidayaan tanaman maka dibutuhkan data real-time mengenai perubahan cuaca saat itu. Maka melalui teknologi pertanian cerdas inilah yang membantu petani dalam mengetahui data yang real tersebut. Efektivitas teknologi pertanian dipengaruhi oleh kesadaran dan kemauan petani dalam menggunakan dan mengadopsi inovasi pertanian. Beberapa teknologi yang termasuk kedalam teknologi smart farming yang dapat dimanfaatkan bagi produktivitas dan efesiensi pertanian salah satunya adalah Agri drone yang dapat dioperasikan untuk menyemprot pembasmi hama dan penyakit (pestisida), penggunaan pupuk cair/padat dan pengairan yang lebih baik sehingga menghindari penggunaan pupuk dan pestisida buatan yang melampaui anjuran yang diberikan. Kehadiran teknologi pertanian cerdas akan membuat budidaya pertanian Indonesia semakin lebih efektif dan efisien untuk menentukan besar atau kecilnya kebutuhan sarprodi. Teknologi smart farming dapat membantu mempermudah pekerjaan petani dalam berusahatani dan bagi kaum muda yang ingin berwirausaha dalam pertanian. Teknologi Smart farming serupa dengan penggunaan teknologi yang diperlukan agar dapat menarik minat kaum muda untuk berpartisipasi dalam sektor pertanian, khususnya untuk pertumbuhan pertanian Indonesia, artikel ini merupakan review dari penelitian terdahulu yang akan ditindaklanjuti dengan penelitian mengenai penerapan teknologi pertanian cerdas.
Research on Vegetable Pricing and Replenishment Model Based on Greedy Algorithm
Authors: Rao Yujing , Wang Canbin
Published: August 2024

This article analyzes the pricing and replenishment decisions of supermarkets, exploring the distribution patterns and correlations between different vegetable categories and individual products. On the other hand, a robust linear programming model is constructed, which can iteratively optimize the corresponding replenishment plan, significantly improving the profitability of supermarkets. This provides important practical significance for the operation and sales of vegetable products in fresh food supermarkets. Through Spearman correlation coefficient analysis, it was found that there is a close relationship between cauliflower and leafy vegetables. The correlation between various vegetable items was processed using K-means clustering method, and the correlation between each item was discussed after classifying the groups. Finally, the grey correlation analysis method was used to further explore the ranking of the correlation between each category and individual product.
How to Deal with Ethical Issues in Engineering Practice
Authors: Zhang Chao
Published: August 2024

With the accelerated pace of engineering and technological innovation, the complexity of engineering and the expanding scope of engineering influence, engineering ethics in the future will become an important issue that must be solved by the main body of engineering practice, and for this reason, the development of engineering ethics education will become an important task for the cultivation of high-quality and excellent engineering talents in the future. The benefits of engineering to human beings are self-evident, however, there are two sides of things, on the one hand, engineering will promote the development of the country, social progress, and bring human beings a more convenient living environment; on the other hand, unreasonable engineering will also bring harm to human beings and hinder the development of society. Therefore, how to prevent engineering risks, maximize the positive benefits of engineering and reduce the negative impacts of engineering is an issue we should pay attention to. Since engineering safety accidents often contain ethical factors, there is a strong necessity and urgency to analyze and prevent them from the perspective of ethics in the study of engineering risks. This paper describes how to deal with ethical problems in engineering practice in five aspects: the importance and prevalence of ethical problems in engineering, the identification of ethical problems in engineering, the exploration of methods for solving ethical problems in engineering, the response to the challenges of ethical problems in engineering, and the education and guidance of engineering ethics.
Challenges and Countermeasures of Environmental Ethics to Engineers
Authors: Li Yang
Published: August 2024

With the development of science and technology, the living environment of human beings has undergone great changes, and the destruction of human beings to the nature has become more and more serious. Engineering activities are the main way for human beings to change the natural environment, and environmental ethical issues in engineering are constantly prominent. As the main participants and implementers of engineering activities, engineers shoulder very important ethical responsibilities. Therefore, it is of certain practical significance to discuss the environmental ethical responsibilities of engineers. This paper discusses the challenges of environmental ethics faced by engineers and the basic principles of environmental ethics, and summarizes the measures and countermeasures for engineers to cope with environmental ethics.
A Quality by Design (QBD) Approach for the Development and Validation of RP-HPLC Method for the Quantification of Silymarin Tablet
Authors:   Department of Pharmaceutical Chemistry, KLE College of Pharmacy Belagavi, KLE Academy of Higher Education and Research, Belagavi-560010, Karnataka, India., Revankar Sanit J. , Pandare Shweta M. ,   Department of Pharmaceutical Chemistry, KLE College of Pharmacy Belagavi, KLE Academy of Higher Education and Research, Belagavi-560010, Karnataka, India., Palled Dr. M. S. ,   Department of Pharmaceutical Chemistry, KLE College of Pharmacy Belagavi, KLE Academy of Higher Education and Research, Belagavi-560010, Karnataka, India., Suryawanshi Dr. Shailendra S. ,   Department of Pharmaceutical Chemistry, KLE College of Pharmacy Belagavi, KLE Academy of Higher Education and Research, Belagavi-560010, Karnataka, India.
Published: August 2024

This study emphasizes the crucial role of Quality by Design (QbD) in developing pharmaceutical procedures, particularly in risk assessment. It demonstrates how QbD principles were applied to create a precise and effective HPLC method for Silymarin Tablets, ensuring consistent quality within specified criteria. The optimized method, developed using a Design of Experiment approach, employs a C18 column (150 mm x 4.6 mm, 5μm) with isocratic elution using a 95:25 ratio of acetonitrile to orthophosphoric acid buffer (pH 3). Peaks were detected using a PDA detector calibrated at 287 nm, with a flow rate of 1.0 mL/min. The column oven temperature was maintained at 25°C, and a 10 μL injection volume was used. Thorough validation, adhering to USP <1225> and ICH Q2 (R1) standards, ensures the method's reliability. Key factors such as accuracy, precision, robustness, limit of detection (LOD), and limit of quantification (LOQ) were comprehensively assessed. The method exhibits exceptional sensitivity, selectivity, efficiency, precision, accuracy, and cost-effectiveness, making it ideal for pharmaceutical analysis of Silymarin tablets. It has been validated to effectively differentiate between marketed products, including those closely resembling the original. This method is intended for routine quality control analysis in the pharmaceutical industry, highlighting its suitability and reliability for ongoing use.
Evaluation of the Electrical Characteristics of a Photovoltaic Solar Module in the Various Climatic Zones of Chad
Authors:   Department of Renewable Energy, National Advanced School of Engineering, University of Maroua, PO Box 58 Maroua, Cameroon / Department of Industrial Engineering and Maintenance, Polytechnic University of Mongo, PO Box 4377 Ndjamena, Chad., Nimir YACOUB Nassian , Dagal frIdriss ,   Beykent University, Electrical Engineering, Ayazağa Mahallesi, Hadım Koruyolu Cd. No:19, Sarıyer / Istanbul., Noel Djongyang ,   Department of Renewable Energy, National Advanced School of Engineering, University of Maroua, PO Box 58 Maroua, Cameroon.
Published: August 2024

The performance of solar photovoltaic modules depends on the availability of solar radiation and the temperature of the solar cells. Knowledge and a good mastery of methods are essential to the design and the choice of the best technology. The chosen method should take into account the nonlinearity effects of the variation of current as a function of irradiation, and the variation of voltage as a function of temperature. In this work, the five-parameter, five-point model is used to evaluate the electrical characteristics of a solar photovoltaic module in the various climatic zones of Chad. Simulations are performed on a 250Wp polycrystalline photovoltaic solar module (SL250CE-36P composed of 72 cells connected in series) with an efficiency of 12.9%. The validation of the models was done by comparing the characteristics of the module in the various climatic zones of Chad. Results showed that most of the parameters depend on both the temperature of the cells and solar irradiance. This study shows that the five-point model is an excellent tool for evaluating the electrical characteristics of solar PV modules in the area. It is an improved method for extracting the five key physical quantities from the solar PV module characteristics. Most of the parameters depend on both the temperature of the cells and the solar irradiance. Accuracy varies depending on operating conditions. The effect of nonlinearity has made it possible to obtain a better match of the characteristics.
An Enlightened Country: The East viewed by Voltaire in The Princess of Babylon
Authors: Zeng Jiawei
Published: August 2024

The eighteenth century marked the advent of a true Chinese exoticism, its growing interest in the search for universal values characterized the spirit and approach of the Enlightenment that swept France. Philosophers began to find foreign models to remedy this ailing country and in Voltaires eyes, China could be an ideal example. This study analyzes the image of China from the pen of Voltaire, mainly in The Princess of Babylon and also in his other works as a complement. It highlights Voltaires great interest in Chinese politics, culture and civilization. The return to the legendary and authentic China that Voltaire describes includes a new conception of history, a morality without religious imperatives, a harmonious vision of the state that he calls enlightened despotism.
Study on the Communication Strategy of Macao Music CultureTaking the Interaction Design of City Walk as an Example
Authors: Huang Jieying , Huang Rushan
Published: August 2024

As a city where East meets West, Macau has a rich historical and cultural heritage, and its music culture, based on its historical background, has a long history of development, with colourful and diverse genres. However, as a tourist city, the publics understanding of Macau is basically confined to the gaming industry. The dissemination of its music is faced with the problems of small scope of dissemination and lack of popularity, etc. Therefore, how to better inherit and protect the music culture of Macau? Therefore, how to better pass on and protect Macaus local culture has become an issue of wide concern to the Macau society nowadays. With the development of the Internet and the changing needs of the public, interactive design came into being, the interactivity of this design can provide a better user experience and increase the attractiveness of the project. As a popular way of travelling nowadays, city walking can make the public feel the city culture better. This design study will conduct fieldwork research on Macaos music culture through fieldwork method, literature research method and data collection method, analyse the form of its integration with urban micro-tourism, and finally design it interactively. In this way, the dissemination of Macaus music culture will be increased and the cultural participation of the public will be strengthened. In addition, the form of city walk can attract tourists of all ages, which is a good guide for the dissemination of Macaus music culture. Moreover, this design can provide the public with a vivid understanding of Macaus music culture, enhance Macaus cultural attractiveness, promote socialisation and interaction in the city, and improve the publics physical and mental health and quality of life. Therefore, this study aims to provide methodological ideas for the communication strategy of Macaus music culture and to provide innovative perspectives for the inheritance of Macaus excellent traditional culture.
Exploring the Fate of Common People in Feudal Society: A Case Study of The Lute
Authors: Cheng Lingxuan
Published: August 2024

In the Yuan Dynasty, common people referred to those living at the lower strata of society, including the proletariat or small producers. Yuan Dynasty dramas depicted numerous images of common people. This paper begins with the image of common people and takes the Yuan Dynasty southern drama The Lute as its text. It deeply analyzes the fate trajectory of Cai Bojie and Zhao Wuniang, who represent common people in feudal society, exploring the reasons behind such tragic fates. Furthermore, it excavates the enduring literary value and contemporary significance of The Lute. The Lute not only reflects society and the era from a literary and artistic perspective but also perceives the tragic fate of common people during the feudal period. Indirectly, it demonstrates the significant contribution of traditional Chinese opera to the reconstruction of cultural concepts and moral-ethical notions.
An Empirical Study of the Impact of the Digital Silk Road on Foreign Trade between China and Countries along the Route - A Quasi-Natural Experiment Based on Silk Road E-Commerce International Cooperation
Authors: Wang Zirong
Published: August 2024

The Digital Silk Road, as the digital extension of the Belt and Road Initiative, aims to enhance international trade and infrastructure development. This study is based on data from 190 countries from 2002 to 2022, using the PSM-DID model and the quasi-natural experimental environment of Silk Road e-commerce international cooperation, to conduct an in-depth study of the impact of the Digital Silk Road (DSR) initiative on trade between China and the countries along the route (countries that have signed the DSR initiative with China). This study draws the following conclusions. First, the DSR initiative has a positive effect on trade between China and the countries along the route, with Chinas import effect on these countries being more significant than the export effect. Second, digital infrastructure has a positive impact on the effectiveness of the DSR initiative. Third, the DSR initiative is more effective when the countries along the route are Asian countries or high-income countries.
Assessment of people's knowledge about the use of analgesics in the city of Baghdad
Authors: Sameen Entsar Khaleel , Najm Shaymaa Hadi , Niazy Shatha Mahmood , Hamza Enass Razzaq
Published: August 2024

Background: Analgesics are among the most important medications that all patients resort to to relieve pain. There are several types of analgesics, including non-opioid analgesics, including paracetamol, and non-steroidal analgesics, including naproxen, ibuprofen, and diclofenac. There are also mixed analgesics. Objective: To assessment of the general public's knowledge about the types of painkillers and how to use them correctly, and to know the risks of using painkillers excessively without a prescription. Method: A descriptive cross-sectional study was conducted to assess people's knowledge and practices about the methods of using analgesics. This study was conducted in the city of Baghdad using a questionnaire form designated for this purpose. The study lasted for four months from 1/1/2024 to 4/4/2024. Result: This study was conducted in Baghdad city to assess people's knowledge about the ways they use painkillers and the availability of painkillers without a prescription. Most of the study participants were in the age group of (24-29) and were employees. Conclusions: People's knowledge about painkillers was healthy, as some people answered that painkillers can be used to relieve pain and reduce body temperature. The most commonly used painkillers were paracetamol, followed by ibuprofen. They had knowledge about the risks of using painkillers, as the majority of the sample answered that using painkillers can cause liver and kidney problems.
Management Assistance at the Diniyah Islamiyah Adam Institute Dusun Numpeng - Jago Village, Praya Subdistrict, Central Lombok
Authors: Muh. Asroruddin Al Jumhuri  , Fatmawati Fatmawati
Published: August 2024

Historically, the birth of madrasah in Indonesia can be seen from two aspects. First, the internal aspect of Islamic teachings prioritizes the obligation to study, including religious knowledge. Second, the external factor is the condition of Islamic education in Indonesia which requires the presence of madrasah as an alternative religious education during modern Dutch colonial educational institutions in Indonesia. Researchers have conducted mentoring activities for managing institutions at the Madrasah Diniyah Islamiyah Adam Institute, Numpeng Hamlet, Jago Village, Praya District. This guidance is focused on the management of teaching staff at the Madrasah. The form of mentoring activities is carried out by being directly involved in the direction of the Madrasah Diniyah Islamiyah Adam Institute, Numpeng Hamlet, Jago Village, Praya District, Central Lombok. Namely, apply yourself in planning, monitoring, and evaluating every activity at Madrasah Diniyah Islamiyah Adam Institute. It is intended that every action and plan be carried out in accordance with what was previously planned by the Head of Madrasah Diniyah Islamiyah Adam Institute and all administrators and teachers.
Kegiatan Membaca Untuk Menumbuhkan Kecintaan Terhadap Buku Sejak Usia Dini
Authors: Aprianti Neli , Husaen Sudrajat  , Syamsul Hadi
Published: August 2024

Saat ini masyarakat diharapkan memiliki minat baca yang tinggi. Buku merupakan sumber ilmu dan pengetahuan yang telah ada sejak dulu dan mudah untuk ditemukan. Banyak yang bisa membaca namun tidak mencintai buku. Hal tersebut disebabkan karena tidak memahami dari apa yang dibacanya, padahal dari buku yang dibaca akan mendapatkan ilmu yang bermanfaat. Kegiatan membaca di desa Sayang-Sayang Kecamatan Cakranegara Kota Mataram merupakan salah satu kegiatan yang harus dilaksanakan secara konseptual dalam menangani krisis kecintaan anak terhadap buku. Mengadakan program kegiatan membaca kepada masyarakat yang ditujukan untuk anak usia dini yang bertujuan dapat memberikan pengalaman dari kegiatan membaca bersama sehingga anak memiliki kecintaan terhadap buku dan gemar membaca. Peran masyarakat (orang tua) sangat diperlukan untuk memotivasi dan membangkitkan semangat mencintai buku khususnya anak usia dini sebagai pondasi untuk lebih mencintai buku, tidak hanya membaca tetapi juga dapat mengerti dari apa yang telah dibacanya dan juga dapat mengaitkan dengan keadaan pengalaman di dunia nyata. Dengan adanya kegiatan pengabdian kepada masyarakat ini, peranan orang tua selaku masyarakat menjadi lebih optimal dalam membantu mengembangkan kecintaan anak terhadap buku. Kegiatan membaca ini merupakan kegiatan yang bersifat partisipatif dengan melibatkan warga masyarakat di desa Sayang-sayang dan akademisi yang membantu dalam kelancaran kegiatan tersebut.
Pengenalan Ruang Terbuka Hijau (RTH) dan Ruang Terbuka Non-Hijau (RTNH)
Authors: Muh Azhari  , Fahruddin Arfianto  , Pienyani Rosawanti  , Putri Irianti Sintaman
Published: August 2024

Kota Palangka Raya adalah salah satu kota yang mengalami pertumbuhan dan perkembangan seiring dengan meningkatnya jumlah penduduk yang menempati wilayah tersebut. Kota Palangka Raya dengan kondisi lingkungannya harus dikelola dengan memperhatikan aspek sustainability dan memikirkan resiko dari pengelolaannya misalnya pengelolaan Ruang Terbuka Hijau dan Ruang Terbuka Non-Hijau yang ada di wilayah tersebut. selain pemerintah yang mengelola lingkungan tersebut, masyarakat juga harus dapat menjaga dan mengelola lingkungan yang sudah diperuntukan untuk kondisi tertentu. sehingga lingkungan tersebut tetap terjaga dengan baik pengelolaan. misalnya dengan melibatkan mahasiswa sebagai bagian dari kegiatan pengabdian, karena mahasiswa dapat menjadi vioner dan agen perubahan. Kegiatan pengabdian yang dilaksanakan dengan teknik observasi dan study kasus ke lokasi RTH dan RTNH dapat meningkatkan dan dapat memberikan pengaruh dalam menjaga lingkungan sesuai dengan fungsi yang sudah ditetapkan. Fungsi RTH dan RTNH diantara sebagai Fungsi Edukasi, Fungsi Wisata, Fungsi Ekonomi dan Fungsi Estetika dan Fungsi Ekologi.
Student Service to Increase Awareness of Clean and Healthy Living Behavior among Students at the Darul Aman Tegal Islamic Boarding School
Authors: Fatmawati  , Muslehudin  , Nursyawani  , Jamilatul Hasanah  , Baiq Nasipah  , Ahmad Zulfakar Ali  , Auni Islihatin Diniati  , Farid Al Rizky  , Fatahilah  , Hadawiyah  , Haerani  , Hulwa Rizki Maulidianti  , Khansa Ummu Syahidna  , Muhammad Azhar  , Nadia Rizki
Published: August 2024

Clean and healthy living behaviour is very important to be applied to daily life in boarding schools, this is shown so that each student can adapt and increase everyone's immune system. Based on this awareness, we, the participants of KKN Pondok Pesantren Darul Aman, invite the students to do sports and cleaning activities. The purpose of this service is to provide an understanding to the students that the importance of maintaining health and cleanliness to foster a sense of care for themselves and the environment. Through this service we succeeded in increasing the awareness of the students about clean and healthy living behaviour, and we also succeeded in increasing the awareness of the students to maintain environmental cleanliness in the boarding school
Pemberian Penguatan Terhadap Sosial Emosional Anak Usia Dini dalam Perspektif Islam Di Era Society 5.0
Authors: Mushab Al Umairi Mushab  , Lillawati Agustine
Published: August 2024

Seminar ini dilatar belakangi sebab adanya ketidakmampuan anak usia dini dalam mengontrol sosial emosional dalam perspektif islam dengan baik terhadap lingkungan, sekolah, keluarga dan juga masyarakat di era society 5.0. Pada masa anak usia dini merupakan masa pembentukan fondasi bagi perkembangan sosial emosional seorang manusia. Maka, ketidakmampuan seorang anak dalam mengontrol sosial emosional yang sesuai dengan lingkungan sekitarnya, dapat menyebabkan anak terkucilkan dari lingkungannya, tidak terbentuknya kepercayaan pada diri sendiri, dan lainnya. Akibatnya anak akan mengalami hambatan dalam perkembangan selanjutnya. Untuk membantu mengurangi ketidakmampuan seorang anak dalam mengontrol sosial emosional yang baik. maka, dibutuhkan upaya bantuan dari orang dewasa. Dalam memberikan bantuan tersebut, orang tua ataupun guru hendaknya memahami proses pengembangan sosial emosional anak usia dini. Rumusan masalah penelitian ini membahas terkait pemberian penguatan terhadap sosial emosional anak usia dini dalam perspektif islam di era society 5.0. Manfaat seminar ini sebagai pertimbangan orang dewasa, baik orangtua ataupun guru memperhatikan interaksi sosial yang baik sesuai dengan kaidah-kaidah Islam. Target dalam seminar ini adalah lembaga-lembaga PAUD di Kel. Gununganyar Tengah, Kec. Gununganyar, Kota. Surabaya. Luaran dalam pengabdian masyarakat ini berupa artikel yang nantinya akan diunggah dalam media massa, jurnal ber ISSN dan HKI artikel. Rencana kegiatan diawali dengan perencanaan meliputi penyusunan materi, penentuan tempat dan administrasi. Kemudian tahap pelaksanaan, meliputi kegiatan pelatihan. Dan bagian terakhir pelaporan kegiatan pengabdian kepada masyarakat.
Literasi Agama Sebagai Alternatif Pendidikan Al-Qur’an Di Desa Lembar Selatan
Authors: Al Jumhuri Muh. Asroruddin , Samsul Hakim  , Alfan Hadi  , Sunardi Utami  , Yuliana  , Sanimah  , Martini  , Saptini  , M. Izrar  , Ridwanullah  , Sadam Paksindra  , Vatimatuz Zakhrah  , Zahroyani  , Muhammad Holkin
Published: August 2024

Pengabdian kepada masyarakat ini bertujuan untuk mengkaji literasi agama sebagai alternatif pendidikan Al-Qur’an di Desa Lembar Selatan, Kabupaten Lombok Barat. Metode yang digunakan dalam pelaksanaan pengabdian ini adalah Tahap perencanaan, tahap persiapan, tahap pelaksanaan. Hasil pengabdian ini menunjukkan bahwa literasi agama memiliki potensi besar dalam meningkatkan pemahaman dan praktik keagamaan masyarakat Desa Lembar Selatan. Meskipun demikian, terdapat tantangan dalam implementasinya, termasuk profesionalitas kerja pelayanan masyarakat yang kurang efektif dan efisien serta kurangnya sarana dan prasarana pendidikan yang memadai.
Pendampingan Public Speaking untuk Meningkatkan Kemampuan Berbicara Bahasa Inggris Siswa SMK Matsaratul Huda Panempan Pamekasan di Era Digital
Authors: Yunitaka B Dinar Vincy , Fitrah Yuliawati  , Jaftiyatur Rohaniyah
Published: August 2024

Tujuan dari program kegiatan pendampingan ini adalah untuk meningkatkan kemampuan soft skill para peserta didik dalam menghadapi era digital untuk bisa berkomunikasi dengan menggunakan bahasa Inggris secara aktif. Sasaran dalam pelatihan ini adalah siswa kelas X di SMK Matsaratul Huda. Kegiatan ini melalui 3 tahapan yaitu; tahap pemberian materi, tahap diskusi, dan tahap praktek. Tujuan utama dari kegitan ini adalah melatih para peserta untuk menguasai teori dan praktek dari public speaking. Hasil menunjukkan bahwa para peserta belum pernah mendapatkan pelatihan khusus tentang public speaking ini, terutama dengan menggunakan bahasa inggris. Awalnya mereka merasa tidak percaya diri dan menganggap diri mereka tidak akan mampu melakukannya. Namun, setelah melihat contoh yang diberikan para peserta mulai tertantang untuk mencoba mempraktekkan kemampuan berbicara dengan menggunakan bahasa inggris. Hasil dari kegiatan ini menunjukkan bahwa para siswa menjadi lebih menguasai materi untuk berkomunikasi, pelafalan kata yang benar sudah meningkat, penyusunan kalimat sudah sesuai dengan struktur bahasa yang baik dan benar. Sebagian besar peserta merasa antusias untuk mencoba mempraktekkan strategi yang telah disampaikan oleh pemateri, khususnya dalam menguasai keterampilan berbicara dengan menggunakan bahasa inggris.
Pelatihan Dan Bimbingan Penulisan Artikel Ilmiah Mahasiswa PGSD UNU NTB
Authors: Azmussya’ni Azmussya’ni , Lalu Abdul Aziz  , Husaen Sudrajat  , Qamariah
Published: August 2024

Tujuan kegiatan Pengabdian Kepada Masyarakat ini adalah memberikan pengetahuan dan pemahaman tentang cara-cara menulis artikel ilmiah pada jurnal ilmiah, menghasilkan karya ilmiah berupa naskah/artikel untuk diterbitkan pada Jurnal Ilmiah, dan produktivitas serta peningkatan kemampuan menulis artikel ilmiah. Khalayak sasaran Pengabdian ini adalah Para mahasiswa UNU NTB yang sedang atau sudah menyusun Skripsi. Metode kegiatan ini adalah Pelatihan selama satu hari tentang penulisan karya ilmiah pada minggu pertama, dan satu hari bimbingan teknis secara langsung penulisan karya ilmiah pada minggu kedua. Hasil dari pengabdian ini menunjukkan peningkatan yang signifikan terhadap pemahaman dan keterampilan mahasiswa PGSD Universitas nahdlatul Ulama Nusa Tenggara Barat dalam membuat artikel ilmiah yang ditunjukkan dengan adanya peningkatan kemampuan menulis mahasiswa, kualitas artikel yang lebih baik, dan produktifitas penulisan artikel ilmiah.
Doença Pulmonar Obstrutiva Crônica: uma revisão de literatura
Authors: Reis Luiza Alves Guerra Scarpelli , Silva Ana Carolina Magalhães Chagas e , Massote Bruno de Barros , Guimarães Felipe Souza , Oliveira Fernanda Caetano Solano , Guerra Gabriel Toledo , Araújo João Pedro de Almeida , Rosa Neto João Salviano , Alves João Vitor Domingos , Ferreira João Vítor Gonçalves , Faria Júlia Rodrigues , Couri Juliana Calil de Carvalho , Casséte Lucas de Carvalho , Pereira Luísa Bambirra , Arguello Victor Fernando Bogado
Published: August 2024

A Doença Pulmonar Obstrutiva Crônica (DPOC) é uma condição respiratória progressiva e debilitante, caracterizada pela obstrução das vias aéreas e pela dificuldade crescente em respirar. Este artigo oferece uma visão abrangente da DPOC, abordando suas definições, impactos clínicos e epidemiológicos, e detalhes fisiopatológicos. A introdução define a DPOC e discute sua importância clínica e o impacto na saúde pública, destacando a prevalência crescente da doença globalmente e a necessidade de estratégias eficazes para seu manejo e prevenção. A seção de epidemiologia explora a prevalência e incidência da DPOC em diferentes regiões e populações, identificando fatores de risco e as variações demográficas, com ênfase nas disparidades entre grupos etários e sociais. A fisiopatologia é analisada, enfatizando os mecanismos subjacentes, como a inflamação crônica e o estresse oxidativo, que contribuem para a obstrução das vias aéreas e o dano pulmonar. O artigo também aborda a etiologia e os fatores de risco associados, com destaque para o tabagismo como principal causador da doença, além da exposição a poluentes e fatores genéticos predisponentes. As manifestações clínicas são discutidas, com foco nos sinais e sintomas típicos e nas complicações comuns. No tratamento, o artigo revisa as abordagens farmacológicas, como o uso de broncodilatadores e corticosteroides, e as terapias não farmacológicas, incluindo a reabilitação pulmonar e o uso de dispositivos respiratórios. A seção de prevenção enfatiza a cessação do tabagismo e a redução da exposição a poluentes como principais estratégias para a prevenção da DPOC. A conclusão reflete sobre os desafios atuais na gestão da doença e as perspectivas futuras, destacando a importância da pesquisa contínua para o desenvolvimento de novas terapias e a melhoria das intervenções existentes.
HUBUNGAN WORK LIFE BALANCE TERHADAP PSYCHOLOGICAL WELL-BEING PADA MAHASISWA YANG MELAKUKAN MBKM
Authors: Intan Dina Sari  , Michelle Tirtabudi  , Fernando Romero Surjo  , Rahmah Hastuti
Published: August 2024

Program Merdeka Belajar Kampus Merdeka (MBKM) yang diluncurkan oleh Kementerian Pendidikan dan Kebudayaan Indonesia bertujuan untuk memberikan kebebasan belajar kepada mahasiswa, memungkinkan mereka untuk memperoleh pengalaman belajar yang lebih fleksibel dan beragam. Penelitian ini bertujuan untuk mengkaji hubungan antara Work Life Balance (WLB) dan kesejahteraan psikologis (psychological well-being) pada mahasiswa yang mengikuti program MBKM. Penelitian ini melibatkan 152 mahasiswa dari berbagai universitas di Indonesia yang telah mengikuti program MBKM. Data dikumpulkan menggunakan kuesioner yang terdiri dari skala WLB dan skala psychological well-being, kemudian dianalisis menggunakan uji korelasi Pearson. Hasil penelitian menunjukkan terdapat hubungan positif yang signifikan antara WLB dan kesejahteraan psikologis dengan nilai korelasi Pearson sebesar 0.788 (p < 0.01). Temuan ini menunjukkan bahwa mahasiswa yang mampu mencapai keseimbangan antara kehidupan akademik, pribadi, dan profesional cenderung memiliki kesejahteraan psikologis yang lebih baik. Penelitian ini menyoroti pentingnya dukungan dari institusi pendidikan dalam membantu mahasiswa mengelola WLB mereka, serta pentingnya memberikan pemahaman dan pelatihan kepada mahasiswa tentang pentingnya WLB.
Organization for laboratory diagnosis of SARS-COV-2 in the conditions of an anti-tuberculosis institution
Authors: Kotova E. A. , Safonova S. G. , Freiman G. E. , Halina S. V. , Aleksandrov A. A.
Published: August 2024

Introduction. In connection with the spread of a new coronavirus infection COVID-19 since 2020, measures have been taken in the city of Moscow to widely diagnose the causative agent of COVID-19. A laboratory PCR department was opened in the State Budgetary Healthcare Institution «MNPC for the fight against tuberculosis of the DZM», taking into account the available material and human resources. Purpose of the study: To generalize the experience of organizing the laboratory service of an anti-tuberculosis institution in the city of Moscow during the spread of a new coronavirus infection. Results. Human and material resources have made it possible to maintain the quality and availability of laboratory diagnostics of biological material from patients receiving treatment at the Moscow Regional Research and Practical Center for Combating Tuberculosis, DZM, during the COVID-19 pandemic. In the period 2020-2022 in total, 90,102 studies of biological material (smears) were carried out by RT-PCR in order to detect COVID-19 RNA. Starting from June 2020 to the present, the PCR department of the KDL Clinic 2 has been studying the direct detection of Covid-19 RNA in biological material using molecular genetic methods based on reverse transcription and polymerase chain reaction (RT-PCR) and the identification of specific immunoglobulin classes IgM and IgG to coronavirus antigens in blood serum (plasma) by the method of immunochemiluminescent analysis (ICLA) of both persons receiving treatment at the State Budgetary Institution of Healthcare Center for Combating Tuberculosis Moscow, and employees.
Venous thromboemboliс complications and tuberculosis: is there an interaction?
Authors: Plotkin D. V. , Titomer A. I. , Reshetnikov M. N. , Schastlivcev I. V. , Loshkareva E. O. , Ivanova D. A. , Sinitsyn M. V. , Bogorodskaya E. M.
Published: August 2024

Venous thromboembolic complications (VTEC) haven’t lost their status as an important medical and social problem for many decades. There are about 300 thousand people die from VTEC in Russia every year. Another significant problem for our country is tuberculosis. Tuberculosis is one of the most common severe infections in the world, most often occurs as a chronic disease and can induce VTEC due to a variety of synergistically acting factors. Previously published studies examined the interaction between tuberculosis and VTEC, but they were based on the data obtained from countries with a high incidence of tuberculosis and a low prevalence of venous thrombosis. An analysis of the literature has shown that tuberculous inflammation determines all three interrelated components of the Virchow’s triad: endothelium inflammatory damage, venous stasis and hypercoagulability. In addition, treatment regimens for the disease with the inclusion of rifampicin also contribute to the development of VTEC due to the pronounced procoagulant properties of the drug. Another equally important agent that potentiates hypercoagulation is the HIV virus, which affects the endothelium and immunocompetent cells. Currently available epidemiological data indicate that HIV infection is associated with an increased risk of VTEC in 2-10 times compared to the general population of the same age. In this context, tuberculosis and HIV/TB co-infection can be considered as a large reversible risk factor for the development of VTEC and included in the prognostic risk assessment scales for acute venous thrombosis and embolism.
Adjuvant therapy in improving the effectiveness of complex treatment of tuberculosis patients in modern conditions
Authors: Russkih O. I. , Komissarova N. V.
Published: August 2024

One of the most important problems in phthisiology remains low indicators of the effectiveness of treatment of tuberculosis patients, especially with drug-resistant MBT. This article presents a review of the possibilities of adjuvant therapy in improving the effectiveness of complex anti-tuberculosis treatment. Adjuvant treatment is prescribed in addition to the anti-tuberculosis chemotherapy and is necessary in the work of a phthisiologist. More than one hundred studies were analyzed, proving that the use of the adjuvant Glutamyl-Cysteinyl-Glycinum dinatrium (Glutoxim) in the complex treatment of tuberculosis is safe and effective.
Nghiên cứu chế tạo vật liệu HgZn3 ứng dụng làm điện cực cho pin thủy ngân oxit-kẽm
Authors: Nguyễn Văn Bằng , Phùng Khắc Nam Hồ , Trần Văn Chinh , Nguyễn Văn Tú , Nguyễn Thị Hoài Phương
Published: August 2024

Pin thủy ngân oxit-kẽm trong môi trường kiềm là pin điện hóa sơ cấp được ứng dụng trong nhiều lĩnh vực khoa học công nghệ, y tế, thiết bị hiện trường,… Để tăng độ bền chống ăn mòn điện cực trong môi trường kiềm cũng như tăng hiệu hiệu suất phóng và dung lượng của pin, kẽm cần được hỗn hống hóa. Bài báo này giới thiệu kết quả nghiên cứu chế tạo và đánh giá đặc trưng của vật liệu HgZn3. Vật liệu được đặc trưng bằng phương pháp nhiễu xạ tia X (XRD), phổ tán xạ năng lượng tia X (EDX), kính hiển vi điện tử (SEM). Kết quả nghiên cứu cho thấy tỷ lệ khối lượng Zn :HgCl2 phản ứng cho sản phẩm hốn hống tốt nhất để làm điện cực âm của pin thuỷ ngân oxit-kẽm là 3:1. Vật liệu có độ tinh thể cao, hàm lượng Hg khoảng 10,8% về khối lượng. Pin xả xuống tới điện áp 0,9 V trong khoảng 209 giờ đạt dung lượng 2823 mAh.
Optimal power management for hybrid electrical vehicle
Authors: To Xuan Dinh  , Nguyen Ngoc Tuan  , Nguyen Ngoc Tien  , Duong Ngoc Khang  , Nguyen Duy Long  , Pham Van Phu
Published: August 2024

This paper introduces an innovative optimal energy management strategy tailored for a hybrid electric-powered hydraulic excavator system. The aim is to bolster power performance, extend the lifespan of power sources, and optimize hydrogen usage. In this system, the fuel cell serves as the primary power source, while integrating supercapacitors and batteries offers benefits such as enhancing power performance and storing regenerative energy for future use. To efficiently distribute power among these three sources and maximize the utilization of regenerative energy, we propose an energy management strategy. This strategy combines fuzzy logic control with a rule-based algorithm. Moreover, we optimize the parameters of the fuzzy logic system using a combination of the backtracking search algorithm and sequential dynamic programming. This optimization aims to reduce hydrogen consumption and prolong the lifespan of the power sources. Simulation results demonstrate that our proposed energy management strategy significantly enhances vehicle performance, improves fuel economy of the hybrid electric-powered hydraulic excavator system, and enhances the durability and efficiency of the battery and supercapacitor systems within the fuel cell system.