bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Efficacy of Platelet-Rich Plasma versus Local Methylprednisolone Injection in Lateral Epicondylitis
Authors: Shaikh Saeed Ahmed , Tahir Muhammad , Ahmed Nadeem
Published: July 2023

Objective: To compare the results of local administration of platelet-rich plasma (PRP) with methylprednisolone in the treatment of tennis elbow.

Methods: This retrospective cohort was conducted at Jinnah Postgraduate Medical Center (JPMC) during January 2017 to April 2018. Patients conservatively managed for lateral epicondylitis with local methylprednisolone injection or PRP injection were approached for possible inclusion in the study at 12 months of treatment. The primary outcome of the study was to determine the Numerical Pain Rating Score (NPRS) on resisted wrist extension. Whereas, the secondary outcomes were quick disability arm, shoulder, and hand score (qDASH), the grip strength and VAS for satisfaction. The baseline, six weeks and three month data on Grip strength, NPRS, and qDASH were extracted from the patients’ medical records maintained at the hospital. The data were analyzed by using SPSS software.

Results: A total of 91 patients were approached, of them 81 (89.01%) agreed to participate. There were 46 (56.79%) who received local methylprednisolone injection and 35 (43.20%) received PRP. At 12 months follow up, there was no difference in NPRS pain scores between the two groups (p=0.691); pain decreased in both groups at six weeks and at 12 months. There was no significant difference in the functional outcome (qDASH score) in both groups. Both groups were equally satisfied with the treatment they had received.

Conclusion: The study concluded that there is no difference between outcome and efficacy of both treatment modalities used for the treatment of tennis elbow in alleviating pain at 12 months.

doi: https://doi.org/10.12669/pjms.39.5.6521

How to cite this: Shaikh SA, Tahir M, Ahmed N. Clinical Efficacy of Platelet-Rich Plasma versus Local Methylprednisolone Injection in Lateral Epicondylitis. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.6521

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clinical efficacy of Thalidomide combined with PAD Regimen in patients with multiple Myeloma
Authors: Wang Yu , Man Qi-hang , Li Chao
Published: July 2023

Objective: To evaluate the clinical efficacy of thalidomide combined with PAD regimen in patients with multiple myeloma (MM).

Methods: It was a Clinical comparative study. A total of 120 patients with MM were admitted at Beijing Aerospace General Hospital from September 2020 to June 2022 randomly divided into two groups, with 60 patients in each group. The study group was treated with thalidomide combined with a PAD regimen (bortezomib, doxorubicin and dexamethasone), while the control group with a PAD regimen alone. After treatment, the therapeutic effect, adverse drug reactions, bone metabolic markers such as serum alkaline phosphatase (ALP) and osteocalcin (OCN) before and after treatment, as well as T-lymphocyte subsets CD3+, CD4+, CD8+ and CD4+/CD8+ levels before and after treatment were compared and analyzed between the two groups.

Results: The total efficacy in the study group was 90%, which was significantly higher than 70% in the control group (p= 0.00). The incidence of adverse drug reactions was 40% in the study group and 38% in the control group, without statistically significant difference (p= 0.85). After treatment, ALP and OCN levels in the study group were significantly higher than those in the control group (ALP, p= 0.01; OCN, p= 0.00), and CD3+, CD4+ and CD4+/CD8+ in the study group also increased significantly compared with those in the control group (CD3+, p= 0.02; CD4+, p= 0.00; CD4+/CD8+, p= 0.00).

Conclusion: Thalidomide combined with a PAD regimen is definitely effective in patients with MM, it can obviously improve immune function and bone salt metabolism, with no increase in adverse reactions but high safety and effectiveness.

doi: https://doi.org/10.12669/pjms.39.5.6815

How to cite this: Wang Y, Man Q, Li C. Clinical efficacy of Thalidomide combined with PAD Regimen in patients with multiple Myeloma. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.6815

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Yield & accuracy of Gastric Lavage in non-expectorating adults with Suspected Pulmonary Tuberculosis
Authors: Ghafoor Lubna , Zuberi Faisal Faiyaz , Khan Ghulam Muqtada , Ismail Maria
Published: July 2023

Objective: To determine the yield of Gastric lavage (GL) in non-expectorating adults with suspected Pulmonary Tuberculosis (PTB) and accuracy of GL-AFB smear with GL-GeneXpert (GXP) by taking AFB culture as gold standard.

Methods: Cross-sectional study on suspected PTB patients was done at Ojha Institute of Chest Diseases during period 16th July 2020 till 15th January 2021. Adult patients of either gender suspected to have PTB and not expectorating were included. GL was performed and sent for AFB smear, GXP and AFB culture. Odds ratio, sensitivity and specificity were calculated.

Results: After informed written consent, 206 patients, mean age was 38.17 ±17.30 years were inducted, including 89 (43.2%) males and 117 (56.8%) females. Gene Xpert, AFB smear & AFB culture were positive in 83(40%), 50 (24%) & 72 (35%) respectively in GL samples. Odds of PTB were 3.95 times higher among patients with ≤1 month of duration of symptoms (aOR 3.95, 95% CI 1.82-8.57, p-value 0.001), 6.24 times higher among patients with weight loss (aOR 6.24, 95% CI 3.03-12.84, p-value <0.001), and 4.22 times higher among patients with cavitation (aOR 4.22, 95% CI 1.99-8.93, p-value <0.001). GL-AFB smear showed sensitivity 63.89%, specificity 97.01%, positive predicted value 92%, negative predicted value 83.3%, and overall diagnostic accuracy 85.4%. Whereas GL-GXP showed sensitivity 94.4%, specificity 88.81%, positive predicted value 81.93%, negative predicted value 96.75%, and overall diagnostic accuracy 90.78%.

Conclusion: Yield of GL significant to detect PTB in suspected cases who are not expectorating. GL-GXP diagnostic accuracy and sensitivity is higher than GL-AFB smear.

doi: https://doi.org/10.12669/pjms.39.5.6972

How to cite this: Ghafoor L, Zuberi FF, Khan GM, Ismail M. Yield & accuracy of Gastric Lavage in non-expectorating adults with Suspected Pulmonary Tuberculosis. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.6972

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
A comparative study between Dydrogesterone alone and combined with Non-Steroidal Anti-Inflammatory Drugs in the treatment of Mild Endometriosis
Authors: Xue Hui-ling , Hao Wan-jiao , Wang Bing
Published: July 2023

Objective: To evaluate the clinical efficacy of dydrogesterone combined with non-steroidal anti-inflammatory drugs(NSAIDs) in the treatment of patients with mild endometriosis.

Methods: This was a clinical comparative study. Eighty patients with mild endometriosis were recruited at Affiliated Hospital of Hebei University, randomly divided experimental group (n=40) and control group (n=40) from March 2022 to March 2023. Both groups started treatment with dydrogesterone on the 5th day of menstruation. Patients in the control group were treated with dydrogesterone monotherapy, while those in the experimental group were treated with mefenamic acid the basis of the therapy of the control group. The clinical efficacy, differences in the levels of humoral immune indexes, the levels of inflammatory factor and the incidence of adverse drug reactions of the two groups was compared and analyzed.

Results: The efficacy of the experimental group was significantly higher than the control group, with a statistically significant difference(P=0.02). The levels of C3 and C4 in the experimental group after treatment were significantly lower than those in the control group, with a statistically significant difference(P=0.00). After treatment, TNF-a, CRP, IL-6 and other indexes in the experimental group were significantly lower than those in the control group, with statistically significant differences(P=0.00). The incidence of adverse reactions after treatment had no statistically significant difference(P=0.45).

Conclusion: Dydrogesterone combined with non-steroidal anti-inflammatory drugs is a safe and effective treatment for patients with endometriosis. It can improve various obvious curative effects, such as marked relief of pain symptoms, reduction of complement and inflammatory factor levels without a significant increase in adverse reactions.

doi: https://doi.org/10.12669/pjms.39.5.7138

How to cite this: Xue H, Hao W, Wang B. A comparative study between Dydrogesterone alone and combined with Non-Steroidal Anti-Inflammatory Drugs in the treatment of Mild Endometriosis. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.7138

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clinical Effects of HBV Infection on Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus
Authors: Duan Lin , Yang Chao , Cai Tingting , Li Wei
Published: July 2023

Objective: To investigate the clinical effects of HBV infection on patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).

Methods: This is a prospective study. Thirty patients with RA and 30 patients with SLE admitted to Affiliated Hospital of Hebei University from January 2020 to December 2021 with co-infection of HBV were randomly selected and divided into two groups. Both groups were given anti-HBV treatment. An additional 60 patients with a healthy physical examination during the same period were also selected as a control group. The disease activity, immune function and serum inflammatory factor levels were compared between the RA group and the SLE group before and after treatment.

Results: After anti-HBV treatment, DAS scores in the RA group and SLEDAI scores in the SLE group were significantly lower than before treatment(P<0.05). The levels of IgG, IgA, IgM and CD8+ in the RA group and the SLE group after treatment were significantly lower than those before treatment. The levels of CCP, RF, ESR and CRP in the RA group before and after treatment were higher than those in the control group(P<0.05). The levels of ESR and CRP in the SLE group before and after treatment were higher than those in the control group, with statistically significant differences(P<0.05).

Conclusion: Patients in the RA and SLE groups after HBV infection have an increased degree of inflammatory response in their organism, an altered normal state of immunoglobulin and T-lymphocyte subsets, and a loss of organism immune function, leading to an increase in disease activity.

doi: https://doi.org/10.12669/pjms.39.5.7232

How to cite this: Duan L, Yang C, Cai T, Li W. Clinical Effects of HBV Infection on Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.7232

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cholera outbreak in 2022 among children in Karachi: Study of cases attending to a Tertiary Care Hospital
Authors: Junejo Samina , Shahid Saba , Khursheed Nazia , Maqsood Sidra , Adnan Fareeha , Khalid Fatimah , Zahid Qurat-ul-Ain
Published: July 2023

Objective & Background: Repeated outbreaks of cholera have occurred in Karachi. Changing patterns in seasonality, serotypes and antibiotic resistance have been observed in these outbreaks. Recently, in the year 2022, a surge of cholera cases has been reported from Karachi during the months of April-June. This study aimed to identify clinical features, antibiotic susceptibility, complications, and response to treatment of V. cholerae infection among children attending Indus hospital, Karachi.

Methods: A retrospective chart review of pediatric patients was conducted for children aged 0-16 years. All children treated for culture-proven cholera infection at Indus Hospital from March to June 2022 were included. Details of clinical features, complications, antibiotic susceptibility, and response to treatment were retrieved from the health management information system (HMIS) of the hospital.

Results: Twenty children were included. The median age was 01 (0.50-3.75) years. There were 9 (45%) males and 11 (55%) females. All the culture isolates belonged to serogroup O1 Ogawa of the Vibrio cholerae. Vomiting and diarrhea were the most common symptoms. Dehydration, acute kidney injury, and shock were seen in 19 (95%), 6 (30%), and 2 (10%) children respectively. Eleven children were admitted with an average hospital stay of 5 (Median-IQR 3-6) days. The isolates were completely susceptible to tetracycline, ciprofloxacin, and azithromycin. Different antibiotics were given which included cefotaxime, ceftriaxone, doxycycline, and ciprofloxacin. All children responded completely to the antibiotics.

Conclusion: In present study all V. cholerae isolates belonged to the O1 Ogawa serotype that showed complete susceptibility to tetracycline, ciprofloxacin, and azithromycin. Dehydration, electrolyte imbalance, and renal impairment were the most common complications observed. Drinking unboiled water was identified as a potential source of cholera in most children. Therefore, advocacy of hygienic practices and disinfection of water supplies is recommended to prevent future cholera outbreaks

doi: https://doi.org/10.12669/pjms.39.5.7395

How to cite this: Junejo S, Shahid S, Khursheed N, Maqsood S, Adnan F, Khalid F, et al. Cholera outbreak in 2022 among children in Karachi: Study of cases attending to a Tertiary Care Hospital. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.7395

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Παράδοση και Αλήθεια στη θεολογία και ερμηνευτική μεθοδολογία του αγίου Ειρηναίου Λυώνος
Authors: Αλεξόπουλος Ανδρέας
Published: July 2023

Στην παρούσα διατριβή ασχοληθήκαμε με το θέμα της Παράδοσης και της Αλήθειας στον άγιο Ειρηναίο Λυώνος. Ο Ειρηναίος είναι ο πρώτος μεγάλος θεολόγος ο οποίος καταπιάστηκε με συγκροτημένο τρόπο με το θέμα της Παράδοσης αυτό καθαυτό και, κατά συνέπεια, με την χριστιανική θεώρηση της Αλήθειας. Η χριστολογική θεώρηση της αλήθειας του αγίου Ειρηναίου, όπως αυτή εκτίθεται στην παρούσα διατριβή, μας «απεγκλωβίζει» από τον ακραίο σκεπτικισμό και τις φονταμενταλιστικές καθηλώσεις και μας ανοίγει στον άπειρο ορίζοντα της θείας υπερβατικότητας. Θεωρούμε δε τον Ειρηναίο προνομιακό συνομιλητή, διότι, αφενός η εποχή του ήταν μια εποχή αυτοπροσδιορισμού της Εκκλησίας έναντι των ποικίλων διανοητικών ρευμάτων του ελληνιστικού κόσμου, αλλά και έναντι των διαφόρων γνωστικών ρευμάτων τα οποία διεκδικούσαν τα εχέγγυα της χριστιανικής ταυτότητας.
StreetDrone Drives Development Ahead
Authors: Knight Helen
Published: July 2023

AI systems can connect to autonomous driving technology for enhanced safety and better communication
Motorsport Inspiration
Authors: Knight Helen
Published: July 2023

Tech used to improve engine power density
The Snowman in Outer Space
Authors: Nathan Stuart
Published: July 2023

Images of most distant object ever visited
Clearing the Air
Authors: Neuenhüskes Klaus
Published: July 2023

Addressing the efficiency and sound-quality challenges of next-generation car audio, by Klaus Neuenhüskes
Speed, Density and Connectivity
Authors: Tyler Neil
Published: July 2023

Just how are connector companies looking to address the demanding requirements of the industrial sector?
Reinventing Flat Education
Authors: Grylls Bethan
Published: July 2023

So far traditional schooling has been restricted to the 2D screen or textbook. Now, ZSpace looks to give it a push into the 21st century.
UK Organisations Lack AI Strategy
Authors: Tyler Neil
Published: July 2023

LACK OF AI STRATEGY, TRAINING AND EXPERIENCE HITTING UK ORGANISATIONS.
Mixed Signals for Machine Learning
Authors: Edwards Chris
Published: July 2023

Maybe AI-enabled systems are here to stay, but the cost of computation remains an issue. Could processing in the analogue domain provide a solution?
Coding Standards
Authors: Bellairs Richard
Published: July 2023

As the dependency on software within automotive development increases, so the importance of coding standards becomes more acute, as Richard Bellairs explains
The Discovery of Drug Delivery from Development Film Forming Hydrogel for Wound Dressing Applications: A Systematic Review
Authors: Annisa Rahmi , Susilowati Retno , Savitri Evika Sandi , Duhita Maharani Retna , Fakurazi Sharida
Published: July 2023

Film Forming Hydrogel is a dosage form that changes shape to film by solvent evaporation after being applied to the wound area. This study aims to present a study to develop film-forming hydrogels with a brief description of the membrane properties formulated from biopolymers for wound application. Over the last ten years, much effort has been conducted to develop new artificial polymeric membranes that meet the demanding requirements for topical applications such as skin wound care. Therefore, this study represents the ideal polymer specifications for wound dressing membranes, such as cross-linked hydrogels compatible with wound dressings. The results of the analysis showed that single-component hydrogels have low mechanical strength. Therefore, recent trends offer composite or hybrid hydrogel membranes to achieve a typical wound with various requirements to meet the characteristic aspects of film-forming hydrogels.
A Systemic Review on Omicron Variant of SARS-CoV-2
Authors: Pappuswamy Manikantan , Chaudhary Aditi , Shitut Anushka
Published: July 2023

As the new strains spread around the world, scientists have been trying to learn more about the different strains, especially Omicron, and how SARS-CoV2 acts in general. Studying historical trends of virus spread and the structure of the virus and its strains, as well as all the mechanisms it needs to survive, can help identify the symptoms and diagnose and treat the disease. The research has shown that the new strains, including Omicron, have a higher rate of mutation and transmissibility. Additionally, due to the rapid spread of the virus, there has not been a significant amount of time to understand the severity of the infection. To better understand the novel variants, a detailed analysis of the basic pathophysiology of the virus is needed. This includes transcriptome analysis for the recombination index to identify variation in the strand. This aided in the diagnostic process, and therapeutics for mutants of the virus could be treated. The Omicron strain is particularly threatening due to its rapid transmission rate and its property of immune evasion, which can make it less vulnerable to vaccination.
Molecular Learning and Memory of Brain Aging
Authors: Poon H. Fai , Yuan Jun , Xu Wayne , Wu Alan F
Published: July 2023

This chapter discusses the molecular basis of learning and memory, specifically the Hebbian theory, which suggests that coincident activation of pre- and postsynaptic neurons leads to modifications in synaptic efficacy, creating associative links between the neurons. Memories are stored as alterations of these synaptic changes. The chapter will also discuss three basic assumptions regarding the neurochemical basis of learning and memory, including the requirement for protein synthesis for long-term memory formation, and the storage of memory in synaptic connections. The passage also discusses long-term potentiation (LTP) as the most frequently studied cellular basis of learning and memory in vertebrates, including its properties such as state-dependence, input specificity, and associativity. LTP is considered an analog of memory since it is a long-lasting alteration in neuronal function that results from a brief period of stimulus.
Pregnancy-associated Cancer and Chemotherapy during Pregnancy
Authors: Romano Alberto , Mastrangelo Stefano , Attina Giorgio , Maurizi Palma , Ruggiero Antonio
Published: July 2023

The diagnosis of pregnancy-associated cancer, although rare, is a condition of great human and social significance and difficult clinical management. A pregnancy-associated neoplasm is defined as a cancer diagnosis made during pregnancy or within 12 months after delivery/abortion. The most common cancers in pregnancy occur most frequently in women of reproductive age with an incidence overall like that observed in non-pregnant women of the same age. This incidence is likely to increase in view of both the expected increase in certain malignancies among young women (particularly breast cancer and melanoma) and the increasing frequency of pregnancies undertaken later in life (fourth and fifth decades of life) that is characterizing modern society. Chemotherapy is generally contraindicated before 12 weeks of pregnancy due to the increased risk of congenital anomalies while exposure in the second and third trimester of pregnancy to chemotherapy has been associated with more growth restriction and preterm delivery. Clinical decisions about the optimal management should consider maternal and fetal characteristics with the involvement of a multidisciplinary team.
Arquivística Musical Histórica aplicada a Arquivos de Bandas de Música
Authors: Coelho Ana Raquel
Published: July 2023

O artigo Arquivística Musical Histórica aplicada a Arquivos de Bandas de Música: um olhar sobre o estado da questão pretende compreender o momento atual da Arquivística Musical Histórica quanto a normas, terminologia e metodologias associadas, quanto ao tratamento arquivístico dado aos Arquivos de Bandas de Música e quanto à importância dos Arquivos nos estudos sobre Bandas de Música militares e civis.

Este artigo assume como assunto central Arquivística Musical Histórica como disciplina em construção que alia um olhar normativo, conceptual e teórico que importa da Arquivística Musical e um olhar problematizante e contextual que importa da Arquivística Histórica. A Arquivística Musical Histórica é assim observada quanto aos seus conceitos, teorias e metodologias, como potencial contributo para o estudo das Bandas de música. Para o efeito procedeu-se a um levantamento do Estado da Arte relativo a autores, conceitos, metodologias e normas para a Arquivística Musical, bem como o levantamento de análise de uma série de Arquivos de Bandas de Música, nacionais e internacionais, tratados arquivisticamente e/ou divulgados online.

Assim, foi possível compreender como, de uma maneira geral, ainda não existe um quadro normativo amplamente aplicado a Arquivos Musicais, como os de Bandas de Música e que o seu tratamento Arquivístico não corresponde a uma tendência, num entanto quando acontece, surge acompanhado da consciência de que tratar e divulgar o Arquivo de uma Banda de Música contribui para a preservação e conhecimento da História do agrupamento em causa.
Análisis judicial del delito de prevaricación administrativa
Authors: Melián Ibiza
Published: July 2023

El presente artículo doctrinal realiza un análisis judicial sobre la prevaricación administrativa. Precepto que se sitúa entre los delitos contra la Administración Pública. En primer lugar, se describen las particularidades necesarias para que se dé el tipo penal y con posterioridad se examina una muestra de cincuenta sentencias condenatorias emitidas por el Tribunal Supremo. Por consiguiente, el método de investigación empleado es un estudio de casos. Donde la variable dependiente u objeto investigado, la prevaricación administrativa, trata de explicarse mediante el tipo de institución afectada, variable independiente. Por tanto, se pretende demostrar la hipótesis de que esta clase de conducta delictual encuentra un mayor abono dentro de las entidades locales, ayuntamientos. Instituciones más proclives a caer en el uso arbitrario del poder.
Memoria democrática: la represión en la enseñanza
Authors: Barreto Martín Eduardo , Bote Díaz Laura , Brais Freire Braña Ramón , Hernández Elena Paula , Louro Pérez María , Narrillos Torres Elena , Olaizola Zárraga Begoña , Vicario Calleja Alejandra Inés
Published: July 2023

El presente artículo analiza la represión franquista en el ámbito educativo, concretamente en relación con los profesionales de centros educativos vinculados a la Universidad de Salamanca. Nuestro estudio se basa en la investigación de los informes de depuración vinculados a la citada universidad en el periodo de la guerra civil española. Los resultados obtenidos permiten realizar una esquematización de las distintas características vinculadas a los represaliados. Hemos encontrado la existencia de un método generalizado que buscaba apartar de sus puestos laborales a los docentes no adeptos al régimen. Es destacable también que los procedimientos estudiados tienen como base un derecho penal de autor que negaba a sus víctimas la tutela judicial efectiva.
Differences in Seedling Ecophysiology and Reproductive Strategy in Two

Impatiens

capensis Ecotypes
Authors: Colao Natalie , Ahmanson Aubrey , Shapiro Alex , Pena-Alfaro Marisa , Farias Lina , Heschel M. Shane
Published: July 2023

Impatienscapensisis a weedy annual plant that grows contiguouslyfrom the Eastern U.S. to the Rocky Mountains through a range of soil conditions, from the moist habitats of the Eastern U.S. to very dry habitats in the West. In this study, weassess differences in the morphology, physiology, and phenologyof
Impatienslines from PA and CO. It is these differences that allow
I. capensisto survive in such a wide range of conditions and form ecotypes. Previous study of these ecotypes has focused on later life-history stages; here, we examine seedling traits in greenhouse conditions. Measurements of stomatal conductance, photosystem efficiency, stomatal density, chlorophyll content index and seedling height differed between CO and PA ecotypes. Because we used inbred lines for this study, we calculated heritability for these seedling traits and considered the evolutionary potential of these populations at an early life-history stage. Furthermore, differences in seed weight and germination time, when contextualized by morphological and physiological data, provide insight into survival and reproductive strategies for these ecotypes.
Hemorrhage From Left Hepatic Artery Pseudoaneurysm as a Complication of Acute Pancreatitis in a Patient With Fibromuscular Dysplasia
Authors: Wang Dennis , Yip Gordon , Szalay David Anthony , Moayyedi Paul
Published: July 2023

Hepatic artery pseudoaneurysms are a rare complication of pancreatitis, and their rupture and bleeding cause high mortality. We present the case of a 76-year-old woman with fibromuscular dysplasia who developed a new left hepatic artery pseudoaneurysm within a week of her first episode of acute pancreatitis and later suffered an acute pseudoaneurysm bleed successfully treated with transcatheter coil embolization. To the best of our knowledge, this is the first case reported of a patient with fibromuscular dysplasia with pancreatitis-related pseudoaneurysm formation. One must consider pseudoaneurysms and associated bleeding as complications of acute pancreatitis because prompt recognition can lead to timely management.
‘Illat, Hikmah, Qiyas: Studi Pemikiran Imam Ar-Razi dan Imam Al-Amidi tentang Penetapan Hukum dalam Istinbat Qiyasi
Authors: Rahman Muhammad Minanur , Wahid Wawan Gunawan Abdul
Published: July 2023

The majority of scholars state that hikmah cannot be considered as an ‘illat (legal cause) due to its abstract and elusive nature. This article aims to examine the views of Imam ar-Razi and Imam al-Amidi regarding hikmah as an ‘illat in Islamic jurisprudence, identify their similarities and differences, and explore the implications for legal deduction. This research uses a literature review methodology with a comparative analysis of the works of Imam ar-Razi and Imam al-Amidi as the primary data sources. The article utilizes usul al-fiqh, a methodological approach to the study of legal issues based on the framework of ‘illat and the hikmah of the law in Islamic jurisprudence. The findings of this article indicate that Imam ar-Razi rejects the use of hikmah as an ‘illat, arguing that hikmah is uncertain and its nature is not constant for every law. On the other hand, Imam al-Amidi suggests that a law accompanied by a clear nature can contain hidden hikmah. The commonality in the thinking of both scholars lies in their rejection of ta’lilul ahkam bi al-hikmah. They argue that hikmah is difficult to ascertain and possesses an abstract nature. There are three key differences between these two scholars: in terms of methodology, thinking, and implications.[Sebagian besar ulama berpendapat bahwa hikmah tidak dapat menjadi ‘illat karena sifatnya yang abstrak dan sulit dipahami. Artikel ini bertujuan untuk mengkaji pemikiran Imam ar-Razi dan Imam al-Amidi mengenai hikmah sebagai ‘illat hukum, menemukan persamaan dan perbedaannya, serta implikasinya terhadap istinbat hukum. Penelitian ini menggunakan metode kepustakaan dengan analisis komparatif berdasarkan karya Imam ar-Razi dan Imam al-Amidi sebagai sumber data utama. Pendekatan yang digunakan dalam artikel ini adalah usul al-fiqh, yang merupakan pendekatan untuk memahami masalah hukum berdasarkan kerangka teori ‘illat dan hikmah hukum dalam usul fiqh. Penemuan dalam artikel ini menunjukkan bahwa Imam ar-Razi menolak penggunaan hikmah sebagai ‘illat dengan alasan bahwa hikmah itu tidak dapat diketahui dengan pasti dan sifatnya tidak tetap untuk setiap hukum. Di sisi lain, Imam al-Amidi berpendapat bahwa hukum yang disertai dengan sifat yang jelas dapat mengandung hikmah yang tersembunyi. Persamaan dalam pemikiran kedua tokoh ini adalah penolakan terhadap ta’lilul ahkam bi al-hikmah. Mereka berpendapat bahwa hikmah sulit untuk ditemukan dan bersifat abstrak. Terdapat tiga perbedaan utama antara kedua tokoh tersebut: dalam metode, pemikiran, dan implikasi hukumnya.]
Pemberian Remisi Terpidana Korupsi: Perlindungan Asasi atau Diskriminasi
Authors: Husna Revando Syahaqul
Published: July 2023

This research puts the issue of granting remissions to corruption convicts which began with the stipulation of PP No. 99 of 2012 concerning Terms and Procedures for the Implementation of the Rights of the Fostered Citizens, it is necessary to have the conditions met first so that in the end the remission can be granted. In fact, the problem of abolishing remissions is not a form of discrimination against the rights of convicts, especially those convicted of corruption, but rather a form of restriction for convicts of corruption so that they do not arbitrarily use their remission rights. The results obtained in this study are the enactment of restrictions on the rights of corruption convicts through strict remission requirements. Through a normative approach, the author explores information through statutory regulations and the regulations under them, namely through Law no. 22 of 2022 and PP No. 99 of 2012.Penelitian ini meletakkan isu pemberian remisi kepada terpidana korupsi yang bermula pada penetapan PP  No. 99 Tahun 2012 Tentang Syarat dan Tata Cara Pelaksanaan Hak Warga Binaan maka perlu adanya syarat yang dipenuhi terlebih dahulu sehingga pada akhirnya remisi tersebut dapat diberikan. Sejatinya problematika penghapusan remisi ini bukanlah sebagai bentuk diskriminasi terhadap hak narapidana khususnya terpidana korupsi, melainkan bentuk pembatasan bagi terpidana korupsi agar tidak semena-mena menggunakan hak remisi tersebut. Adapun hasil yang didapat pada penelitian kali ini adalah berlakunya pembatasan hak terpidana korupsi melalui syarat ketat keberlakuan remisi. Melalui pendekatan normatif, penulis menggali informasi melalui peraturan perundang-undangan beserta peraturan di bawahnya yakni melalui UU No. 22 Tahun 2022 dan PP No. 99 Tahun 2012.
IMPROVING STUDENT LEARNING OUTCOMES: BRAIN-BASED LEARNING WITH A MIND MAPPING MODEL AFTER THE COVID-19 PANDEMIC
Authors: Subiyantoro  , Dicky Artanto  , Afiq Fikri Almas
Published: July 2023

This article examines related learning methods that can attract learners to learn the subjects of the Curriculum with a brain-based learning approach or brain-based Learning. This method uses field research at Muhammadiyah 1 Prambanan Junior High School by interviewing several respondents, namely representatives of 7th-grade students, field observation, and documentation analysis using data in the form of documents and related data sources needed. Data analysis using Miles and Huberman methods is by data collection, data reduction, presentation of data, and withdrawal of conclusions or data verification. The research results show that the learning process with a brain-based learning approach with mind mapping methods significantly impacts learners' learning interest in the subjects of The Islamic Civilization (Tarikh) in Grade 7. The trial results showed that almost all pupils' grade scores increased, affecting average grades in each class. The learners' enthusiasm is also seen when they do mind mapping with great earnestness. However, in this learning model with mind mapping, some shortcomings exist. Namely, it will be difficult for students who are not interested to understand the material quickly.
evolution of death and immortality ideas from russian cosmism to synergy
Authors: Tumarkina Lydia V.
Published: July 2023

In this paper, death and immortality ideas of Russian cosmists are in syncretic way put together with key ideas in postmodern philosophy. The problem considered in world philosophy on creating co-evolutionary conditions for the emergence of «immortal» man is illustrated by a wide variety of ideas and concepts. This paper contains innovative ideas of the Russian cosmists as the starting point of the research. Special attention is paid to the extraordinary teachings of N. F. Fedorov, who is the founder of Russian Cosmic philosophy. Using the system-diachronic method and technologies of ascending from the abstract to the concrete, the author compares the ideas of Russian cosmism with manifest concepts of modern philosophy (synergetics, phenomenology, transhumanism). The author also gives the most striking facts of discoveries of modern natural science and draws conclusions about ideas of Russian cosmists that have been put forward ahead of their time and retained their relevance and ontological potential until now. The paper presents the prospects for further studying the heritage of Russian cosmism to search for philosophical tools that could, without going beyond the limits of ethical universals, successfully combine the controversial theoretical directions of modern philosophy for the future positive practical development of society.
pasividad antropológica de la culpa
Authors: Fuster Camp Ignasi
Published: July 2023

El artículo pretende explorar la línea de la pasividad —o redundancia— de la culpabilidad en el hombre. La cuestión existencial es la posibilidad de superación de la culpa. Así pues, se recorren y analizan los diversos momentos antropológicos generados por la culpa: el sentimiento de culpa y el arrepentimiento humano. Existe una experiencia privilegiada para la superación de la culpa: el perdón humano. Afrontamos finalmente el acto antropológico del perdón: sus posibilidades, su verdad y sus límites.
Una mirada comprensiva a la gestión de la Migración de Retorno en Colombia desde una Perspectiva Transnacional
Authors: Raigosa Mejía Marisol , Dishington Leal Alejandra Isabella
Published: July 2023

Los objetivos de este artículo son, primero, identificar la orientación de la política y los programas de atención a través de los cuales el Estado colombiano ha configurado el soporte discursivo frente a la migración de retorno, con el fin de establecer hacia quiénes se ha enfocado este; segundo, presentar una aproximación crítica a la orientación básica -economicista e instrumental- sobre la que se sustentan dichas medidas de conformidad con lo establecido desde la perspectiva transnacional de la migración de retorno, la cual propone reconocer que algunos migrantes y sus descendientes son influenciados por continuos vínculos con los países de origen que sobrepasan las fronteras nacionales. Mediante un enfoque cualitativo se hizo uso de estrategias de recolección de información como la revisión documental y las entrevistas semiestructuradas, a partir de las cuales se concluyó que es necesario continuar trabajando desde la academia y los escenarios políticos en la compilación de una ley que recoja lo que está estipulado de forma diseminada en decretos, y de esta manera lograr asumir desde una perspectiva institucional el abordaje del fenómeno y el tratamiento del mismo.
Reseña de Allier Montaño Eugenia: 68. El movimiento que triunfó en el futuro. Historias, memorias y presentes
Authors: Confino Hernán
Published: July 2023

Reseña del último libro de Eugenia Allier Montaño: 68. El movimiento que triunfó en el futuro. Historias, memorias y presentes. Bonilla Artigas Editores, 2021.
الاوضاع السياسية في بلاد داسن في القرن السادس عشر
Authors: Hasan Nazar A.
Published: July 2023

كانت بلاد الكورد خلال العهد العثماني تضم عدد كبیر من الإمارات والزعامات التي اختلفت من حيث طبيعة وضعها في إطار الدولة العثمانية ودرجة استقلاليتها في إدارة أمورها الداخلية. وقد أنجز الأمير الكوردي شرفخان البدليسي في سنة ١١٠٥هـ / ١٥٩٦م تأليف كتابه الشهير "شرفنامە " عن تاريخ الإمارات الكوردية، لكنه أهمل، لأسباب غير واضحة، الكتابة عن بعض تلك الإمارات التي بقي تاريخها طي النسيان. تحاول هذه الدراسة إلقاء الضوء على إحدى الإمارات الكوردية المنسية وهي إمارة داسن والتركيز على جغرافية داسن التي تشكل منطقة البحث والتطورات السياسية والأمنية التي حصلت في بلاد داسن في القرن السادس عشر. ونظراً لقلة المصادر والمراجع التي تتحدث عن هذه الإمارة فقد اعتمدت هذه الدراسة بشكل أساسي على الوثائق و المصادر العثمانية الأصلية ، لاسيما الوثائق الواردة في سجلات (دفاتر المهمة) و (دفاتر توجيهات) ، وهي الأوامر السلطانية التي وجهت الى الولاة العثمانيين و الأمراء الكورد المحيطين ببلاد داسن ، وتتضمن معلومات مهمة حول الكثير من نواحي تاريخ هذه المنطقة، كما تشكل هذه الدراسة مادة مهمة لدراسة تاريخ انتشار الديانة الايزيدية في منطقة داسن و العلاقات بين زعماء هذه الطائفة و السلطات في الولايات و الألوية العثمانية.
Regionale Auswirkungen der Abrüstung auf den Arbeitsmarkt in Bayern
Authors: Sträter Detlev
Published: July 2023

Der Abbau der Militär- und Rüstungspotentiale im Zuge des international vereinbarten Abrüstungsprozesses hat, regional unterschiedlich, direkte und indirekte Beschäftigungswirkungen zur Folge. In Bayern, das durch Bundeswehr und US-Streitkräfte bisher militärisch hoch belastet war, sind davon besonders deren Zivilbeschäftigte vor allem in den strukturschwachen Regionen, aber auch mehrere tausend Beschäftigte in den südbayerischen Rüstungsproduktionszentren betroffen. Im vorliegenden Beitrag werden der arbeitsmarktpolitische Handlungsbedarf sowie beschäftigungssichernde Maßnahmen lokaler und regionaler Arbeitsmarktkonzepte diskutiert.
City-Marketing und City-Management – Instrumente zur Abstimmung von Stadt- und Einzelhandelsentwicklung und zur Sicherung einer mittelständisch geprägten Einzelhandelsstruktur in den neuen Bundesländern?
Authors: Holl Stefan
Published: July 2023

Als neues Instrument oder Verfahren zieht seit Ende der 80er Jahre City-Marketing ein gut Teil des Interesses der Fachöffentlichkeit (1) auf sich. City-Marketing betont die Verbindung zwischen Stadt- und Wirtschaftsentwicklung und steht für eine stärkere Ausrichtung der Stadtentwicklung an Marktmechanismen.Kritiker der Leistungsfähigkeit der Städte bei der Lösung innerstädtischer Probleme gehen weiter: Sie fordern eine Organisation, die mit einer aus der Wirtschaft abgeleiteten Effizienz die Cityprobleme bearbeitet (2), ein City-Management, welches etwa auch dem ortsansässigen mittelständischen Handel Hilfestellungen anbieten kann.Für beide Begriffe liegen noch keine allgemein akzeptierten Definitionen vor – beide Begriffe werden vielfach auch synonym verwandt (3). Da im Vordergrund des vorliegenden Beitrags die Frage steht, welchen Beitrag City-Marketing zur Stärkung des mittelständischen Einzelhandels in den neuen Bundesländern leisten kann, wird im ersten Abschnitt einleitend das Spannungsverhältnis zwischen Einzelhandel und Städtebau unter besonderer Berücksichtigung der speziellen Problemstellungen in den neuen Bundesländern skizziert.Der zweite Abschnitt fragt zunächst nach den Gründen für den Erfolg der Konzepte City-Marketing und City-Management voneinander, bevor dann die Erfahrungen mit ihnen in den alten Bundesländern aufgezeigt werden.Im dritten Abschnitt werden die besonderen Probleme des mittelständischen Einzelhandels in den neuen Bundesländern vertieft, bevor im abschließenden Kapitel der Frage nachgegangen werden soll, ob City-Marketing und CityManagement im Spannungsfeld zwischen Einzelhandel und Städtebau taugliche Konzepte zum Aufbau einer mittelständisch geprägten Einzelhandelsstruktur darstellen.
Correlation of Hemoglobin Levels with Nutritional Status in Adolescent Girls: A Health Promotion Perspective
Authors: Sari Rati Purnama , Silaban Evi Maria Lestari , Merry Yussie Ater
Published: July 2023

Background: Women during pregnancy, childbearing age, and adolescents are prone to anemia. The prevalence of anemia in adolescents in Indonesia in 2018 reached 32%. The objectives of this study were to determine the correlation between nutritional status with the incidence of anemia in adolescent girls.Method: Describe briefly the main methods or treatments applied. This study is an analytical survey with a cross-sectional design. The population in this study was student girls in Padang City in 2022.The instrument used to measure hemoglobin was a digital Hb measuring instrument. The nutritional status in this study used the measurement of the nutritional status of adolescents with the indicator of BMI according to age. Correlative analytic test with ordinal scale data used the Kendall's tau test.Results: Based on the results of this study, was known that most of the 71.9% of adolescent girls whose nutritional status is normal. Most of the adolesce girls (87.5%) had normal hemoglobin levels, and as many as 12.5% adolensce girls had anemia who were not menstruating. Nutritional status (BMI/age) and hemoglobin levels were not correlated. Nutritional status is not a factor causing anemia in adolescent girls. It is necessary to investigate the prevalence of anemia in adolescent girls during menstruation as a comparison.
Effectiveness of Health Promotion Videos in Preventing Breast Cancer
Authors: Adyani Kartika , Realita Friska , Maulidina Anisa Alya
Published: July 2023

Background: Breast cancer is the second most common type of cancer among women worldwide. Out of a total of all types of cancer (348,809 cases), breast cancer contributed 58,256 (16.7%). Lack of information, knowledge, and awareness about breast cancer often results in adolescents not taking the initiative to engage in early detection, which is the first step in preventing breast cancer. The objective of this study is to determine the educational effectiveness of breast self-examination (BSE) using leaflets and audio-visual media on the knowledge and attitudes of female students at SMA Negeri 1 Bukateja.Method: A quasi-experimental research design was employed, utilizing consecutive sampling. The study included two research groups with a total of 64 participants. Data analysis was conducted using the Chi-square test.Results: The effectiveness of audio-visual media and leaflets in increasing knowledge and attitudes of female students about BSE was found to be statistically insignificant (p-value > 0.05). Therefore, it can be concluded that both leaflets and audio-visual media have a similar effectiveness in improving adolescent attitudes towards BSE. Future researchers should consider utilizing alternative media, such as WhatsApp, for BSE education, as previous studies have shown it to be more effective than leaflets in enhancing knowledge and attitudes among young women regarding early detection of breast cancer.
Pre-Trained Embeddings for Entity Resolution: An Experimental Analysis
Authors: Zeakis Alexandros , Papadakis George , Skoutas Dimitrios , Koubarakis Manolis
Published: July 2023

Many recent works on Entity Resolution (ER) leverage Deep Learning techniques involving language models to improve effectiveness. This is applied to both main steps of ER, i.e., blocking and matching. Several pre-trained embeddings have been tested, with the most popular ones being fastText and variants of the BERT model. However, there is no detailed analysis of their pros and cons. To cover this gap, we perform a thorough experimental analysis of 12 popular language models over 17 established benchmark datasets. First, we assess their vectorization overhead for converting all input entities into dense embeddings vectors. Second, we investigate their blocking performance, performing a detailed scalability analysis, and comparing them with the state-of-the-art deep learning-based blocking method. Third, we conclude with their relative performance for both supervised and unsupervised matching. Our experimental results provide novel insights into the strengths and weaknesses of the main language models, facilitating researchers and practitioners to select the most suitable ones in practice.
LEON: A New Framework for ML-Aided Query Optimization
Authors: Chen Xu , Chen Haitian , Liang Zibo , Liu Shuncheng , Wang Jinghong , Zeng Kai , Su Han , Zheng Kai
Published: July 2023

Query optimization has long been a fundamental yet challenging topic in the database field. With the prosperity of machine learning (ML), some recent works have shown the advantages of reinforcement learning (RL) based learned query optimizer. However, they suffer from fundamental limitations due to the data-driven nature of ML. Motivated by the ML characteristics and database maturity, we proposeLEON-a framework for ML-aidEd query OptimizatioN.LEONimproves the expert query optimizer to self-adjust to the particular deployment by leveraging ML and the fundamental knowledge in the expert query optimizer. To train the ML model, a pairwise ranking objective is proposed, which is substantially different from the previous regression objective. To help the optimizer to escape the local minima and avoid failure, a ranking and uncertainty-based exploration strategy is proposed, which discovers the valuable plans to aid the optimizer. Furthermore, an ML model-guided pruning is proposed to increase the planning efficiency without hurting too much performance. Extensive experiments offer evidence that the proposed framework can outperform the state-of-the-art methods in terms of end-to-end latency performance, training efficiency, and stability.