bluuebunny/crossref_metadata_2025 huggingface dataset:
MicroRNA-204/CREB5 axis regulates vasculogenic mimicry in breast cancer cells
Authors: Contreras-Sanzón Estefania , Palma-Flores Carlos , Flores-Pérez Ali , M. Salinas-Vera Yarely , B. Silva-Cázares Macrina , A. Marchat Laurence , G. Avila-Bonilla Rodolfo , N. Hernández de la Cruz Olga , E. Álvarez-Sánchez María , Pérez-Plasencia Carlos , D. Campos-Parra Alma , López-Camarillo César
Published: May 2022

BACKGROUND: Vasculogenic mimicry (VM) is characterized by formation of three-dimensional (3D) channels-like structures by tumor cells, supplying the nutrients needed for tumor growth. VM is stimulated by hypoxic tumor microenvironment, and it has been associated with increased metastasis and clinical poor outcome in cancer patients. cAMP responsive element (CRE)-binding protein 5 (CREB5) is a hypoxia-activated transcription factor involved in tumorigenesis. However, CREB5 functions in VM and if its regulated by microRNAs remains unknown in breast cancer. OBJECTIVE: We aim to study the functional relationships between VM, CREB5 and microRNA-204-5p (miR-204) in breast cancer cells. METHODS: CREB5 expression was evaluated by mining the public databases, and using RT-qPCR and Western blot assays. CREB5 expression was silenced using short-hairpin RNAs in MDA-MB-231 and MCF-7 breast cancer cells. VM formation was analyzed using matrigel-based cultures in hypoxic conditions. MiR-204 expression was restored in cancer cells by transfection of RNA mimics. Luciferase reporter assays were performed to evaluate the binding of miR-204 to 3′UTR of CREB5. RESULTS: Our data showed that CREB5 mRNA expression was upregulated in a set of breast cancer cell lines and clinical tumors, and it was positively associated with poor prognosis in lymph nodes positive and grade 3 basal breast cancer patients. Silencing of CREB5 impaired the hypoxia-induced formation of 3D channels-like structures representative of the early stages of VM in MDA-MB-231 cells. In contrast, VM formation was not observed in MCF-7 cells. Interestingly, we found that CREB5 expression was negatively regulated by miR-204 mimics in breast cancer cells. Functional analysis confirmed that miR-204 binds to CREB5 3′-UTR indicating that it’s an ulterior effector. CONCLUSIONS: Our findings suggested that CREB5 could be a potential biomarker of disease progression in basal subtype of breast cancer, and that perturbations of the miR-204/CREB5 axis plays an important role in VM development in breast cancer cells.
Smartphone and internet addiction as predictors of cyberloafing levels in students: A mediated model
Authors: Öztürk Mücahit , Kerse Gökhan
Published: May 2022

This study aims to determine the predictors of cyberloafing behaviors of university students. In this context, we examined the effects of smartphone and internet addiction variables on cyberloafing levels. Besides, the mediator effect of internet addiction was determined in the impact of smartphone addiction on cyberloafing. We conducted the questionnaire-based study with 341 students studying at different departments of a state university (faculty of education, faculty of engineering, and vocational school) in Turkey. Participants consisted of 182 male and 159 female. Students filled out the smartphone addiction scale, the internet addiction scale, and the cyberloafing activities scale. The data obtained from the 5-point Likert type scales were evaluated with correlation and regression analyses. The results showed that there is a significant positive relationship between smartphone addiction, internet addiction, and cyberloafing. While internet addiction was a predictor of cyberloafing, it mediated the effect of smartphone addiction on cyberloafing. We discussed the results of this study and offered suggestions for future research.
Aspect term extraction and optimized deep fuzzy clustering-based inverted indexing for document retrieval
Authors: Chandwani Gunjan , Ahlawat Anil , Dubey Gaurav
Published: May 2022

Finding good relevant documents for query optimization is a well-known difficulty in the field of document retrieval. This paper develops a novel approach, named Exponential Aquila Optimizer (EAO)-based Deep Fuzzy Clustering for retrieving the documents. The proposed technique effectively finds the relevant documents and tries to understand the relationship among the documents and queries in terms of the significance of documents for query optimization. Here, the Deep Fuzzy Clustering is employed for performing cluster-based inverted indexing where the Training procedure of Deep Fuzzy Clustering is done using the developed optimization algorithm, named EAO. Meanwhile, the developed EAO is newly designed by the incorporation of EWMA and AO. In addition, complex query matching is done using the Tversky index for the user-based queries, such as multigram queries and semantic queries. On the other hand, the RV coefficient is accomplished for performing query optimization for relevant document retrieval. The proposed technique achieves better performance in terms of the performance metrics, like precision, recall, and F-measure with the maximum precision of 1, maximum recall of 0.956, and maximum F-measure of 0.977, respectively.
Two-stage container keyhole location algorithm based on optimized SSD and adaptive threshold
Authors: Huang Qingfeng , Zhang Yujie , Huang Yage , Mi Chao , Zhang Zhiwei , Mi Weijian
Published: May 2022

The automation transformation of container lifting operations is one of the main technical issues in Rail-Truck intermodal transportation. To solve this problem, this paper analyzes the advantages and disadvantages of several existing container positioning methods, and proposed a container corner holes location detection method based on lightweight convolutional neural network and adaptive morphological image processing algorithm. This method locates the container through a visual sensor that shoots from top to bottom. In order to improve the positioning accuracy and calculation speed while maintaining a high recognition rate, this method first uses a lightweight SSD detector to quickly detect the rough coordinates of the container corner hole in the image. On this basis, the smallest rectangle detection method based on adaptive HSV filtering is used to detect the precise coordinates of the corner hole in the image. Experiments show that the recognition rate of this algorithm in the initial positioning process reaches 94.2%, the recognition rate of secondary positioning reaches 87.4%, and the final positioning error is lower than 3.765 pixels and 2.81 pixels in the heading and lateral directions, respectively. The overall calculation time of the algorithm can realize the positioning calculation of 30 frames per second, which shows that this method takes into account the characteristics of high measurement accuracy and high calculation speed on the basis of high recognition rate.
Robot motion planning with orientational constraints based on offline sampling datasets
Authors: Zhang Qinglei , Wang Zhangpeng , Duan Jianguo , Qin Jiyun
Published: May 2022

Currently available algorithms developed for planning robot motion paths in configuration spaces with both obstacle avoidance constraints and end-effector pose constraints suffer from low sampling rates, long computation times, and requirements for specific manipulator structures. The present work addresses this issue by developing an improved sampling-type motion planning algorithm based on a modified form of the rapidly-exploring random tree (RRT) algorithm. The sampling process is based on the standard premise that the constrained manifold is continuous within a particular range. Therefore, configurations that meet the specific constraints associated with a proscribed motion planning task are sampled in advance, and those configurations meeting the constraints are stored in an offline configuration dataset that is employed exclusively in the RRT process. Accordingly, the proposed algorithm facilitates a greatly streamlined motion planning process for manipulators with high degrees of freedom. The computational speed and planning precision of the algorithm are further enhanced by introducing a target bias mechanism and applying an adaptive mechanism to improve the obstacle collision detection performance. The high motion-planning performance of the proposed algorithm is verified by comparisons with the performances of other state-of-the-art RRT-based algorithms based on numerical simulations.
The highways and side roads of statistical capacity building
Authors: Lokshin Michael
Published: May 2022

This paper proposes an approach to guide statistical capacity building in developing countries using an analysis based on components of the World Bank’s Statistical Performance Indicator on a sample of 215 countries. The approach demonstrates the importance of expanding traditional capacity-building activities to include programs to strengthen and better monitor the ability of National Statistical Systems (NSS) to respond to user data needs. Based on this analysis, the paper recommends a two-step strategy for building and enhancing the statistical capacity of national statistical systems in developing countries. The strategy creates a sustainable trajectory for developing NSSs that meets the growing demands of local and global data users. The paper emphasizes the importance of donor coordination and South-South learning initiatives for international capacity-building efforts.
Evaluating the influence of 6MV and 10MV photon beams on cervical cancer volumetric-modulated arc therapy plans
Authors: He Dong-Cheng , Zhu Zhi-Jian , Zhang Xiao-Ye , Zhang Yan , Hong Jun , Shi Ting-Ting , Han Ji-Hua
Published: May 2022

BACKGROUND: Cervical cancer is a common gynecological cancer among women worldwide. OBJECTIVE: To determine the effects of 6 MV and 10 MV volumetric-modulated arc therapy (VMAT) photon beams on the target volume (TV) planning and critical organs in cases of cervical cancer. METHODS: Fifty patients with carcinoma of the cervix who underwent radiotherapy were selected. The transverse diameter (T) of the cross section of the upper edge of the sacroiliac joint on computerized tomography (CT) images of the patients was measured, and the mean value was calculated as 34 cm. All patients were divided into two groups: Group A (T < 34 cm) and Group B (T > 34 cm). The VMAT plans were generated using 6 MV and 10 MV plans separately. The prescription dose was 47.5 Gy, and the daily dose was 1.9 Gy. RESULTS: In Group A, the planning target volume (PTV) dose assessment parameters of 6 MV and 10 MV plans and their homogeneity and conformity indices were not statistically significantly different. A significant difference was observed between the 6 MV and 10 MV plans for the PTV dose assessment parameters and the homogeneity index of the plans for Group B. The monitor units (MUs) of the 10 MV plans were lower than in the 6 MV plans in both Groups A and B, and the difference was statistically significant. The assessment parameter V40 Gy of both the rectum and bladder in the 6 MV plans was smaller than the corresponding parameter in the 10 MV plans in Group A; in Group B, the assessment parameter V50 Gy of the rectum in the 10 MV plans was smaller than in the 6 MV plans. CONCLUSION: When T < 34 cm, 6 MV energy is more suitable for the external irradiation of cervical cancer. When T > 34 cm, 10 MV energy is more suitable for cervical cancer radiotherapy. Therefore, 10 MV should be considered for patients with a large abdominal size.
Evaluation of tooth demineralization using laser-fluorescence in dental school patients undergoing orthodontic treatment: A clinical study
Authors: Cerón-Zamora Eduardo , Scougall-Vilchis Rogelio José , Lara-Carrillo Edith , Contreras-Bulnes Rosalía , Robles-Bermeo Norma Leticia , Mendoza-Rodríguez Martha , Medina-Solís Carlo Eduardo , Maupomé Gerardo
Published: May 2022

BACKGROUND: Adverse effects can occur during orthodontic treatment. OBJECTIVE: To evaluate the relationship between prevalence and severity of enamel demineralization using a laser-fluorescence device, with length of orthodontic treatment time. METHOD: A cross-sectional study was conducted in 60 patients in a university orthodontic clinic. A clinical examination to establish demineralization at four sites on each tooth (premolar to premolar) was performed using the DIAGNOdent pen. The dependent variable was enamel demineralization, from which the prevalence (at least one affected site), extension (percentage of affected teeth) and adjusted average (average of the mean DIAGNOdent values per tooth) were calculated. The length of time for orthodontic treatment was determined in months. Various sociodemographic and clinical covariates were included. RESULTS: Average number of months under orthodontic treatment was 26.37 ± 24.81 months. Prevalence of enamel demineralization was 80.0%, its extension was 21.9% ± 17.2 and adjusted average of DIAGNOdent values was 6.09 ± 1.75. By quadrant, the teeth most affected were 14 (34.4%), 24 (25.0%), 31 (30.2%) and 44 (33.3%). No significant relationship (p> 0.05) was observed between enamel demineralization and length of time under orthodontic treatment. CONCLUSIONS: A high prevalence of dental demineralization was observed. In this sample, no relationship was observed between months under treatment and dental demineralization, or with other variables included in the study.
Perspectives on the Immune System in Sepsis
Authors: Stancioiu Felician , Ivanescu Bogdan , Dumitrescu Radu
Published: May 2022

Beyond the modifications shown by the biochemistry labs, profound and ample modifications are seen in septic patients at a molecular level stemming from DNA translation and gene expression, manifested as unique profiles of mRNA (messenger), as well as non-coding, functional RNAs: miRNA (micro) and lncRNAs (long non-coding). Counteracting these modifications requires treatement with pleiotropic molecules and/or combination of molecules and opens the possibility of future treatments with arrays of siRNAs and/or specific panels of small molecules tailored for each patient subpopulation.
A STUDY ON THE IMPACT OF GREEN ENVIRONMENTAL AND HRM PRACTICES ON THE ORGANIZATIONAL PERFORMANCE IN SELECT ORGANIZATIONS, AP, INDIA
Authors: Rao M.V.K. Srinivasa
Published: May 2022

This research paper aims to analyze the Impact of Green Environmental Initiatives and Green HRM Practices on organizational Performance in the Educational Sector. The Intermediate, UG, PG and Professional Colleges in Andhra Pradesh are quite competitive and resourceful but presently facing a lot of challenges due to quality transformations adopted and imposed by Regulatory Authorities via, BIEAP, State Universities, AICTE, UGC,APSCHE, NAAC, NBA and Several Self Quality Initiatives, to be instigated in order to get Sustainability, High Organizational Performance and Development etc. The main objective of the present study is to find out the influence of Green Environmental and GHRM Practices on Organizational Performance of the select organizations in educational sector, Andhra Pradesh, India. For this purpose, the quantitative cross-sectional study design approach has been adopted, and the data generated from 330 academicians from various educational intuitions in Andhra Pradesh, India and analyzed through testing Hypothesis with the help of SPSS 25. The study has revealed that the significant Green Initiatives and HRM variables carry their influences on Organizational Performance in terms of Results and Admissions.
THE USE OF VETERINARY MACROSCOPIC ANATOMY AS AN EDUCATIONAL INSTRUMENT IN ELEMENTARY AND HIGH SCHOOL IN BRAZIL
Authors: Furtado Gil Dutra , Fernandes Erypaula Josefa Gonçalo do Nascimento , Duarte Grazielly Diniz , Duarte Gabrielly Diniz , Sobral Felipe Eduardo da Silva
Published: May 2022

Este artigo trata da anatomia macroscópica veterinária como ferramenta educacional no ensino fundamental e médio no Brasil e a forma como é ensinada nas escolas públicas brasileiras. O objetivo principal é conhecer o desenvolvimento do ensino macroscópico na educação básica, a fim de demonstrar a relevância de se conhecer a anatomia dos animais na prática. Sabe-se que o ensino de anatomia humana e animal está vinculado ao ensino das ciências biológicas, porém, percebemos que o ensino / aprendizagem desses alunos tem sido insuficiente, pois apresentam aulas práticas associadas ao desinteresse de. anatomia macroscópica, havendo também uma certa indiferença por parte dos professores e da própria instituição em fornecer recursos que levem os professores a trazer o conhecimento da teoria para a prática. Este estudo é evidenciado pelo caráter qualitativo, retirando do objetivo da pesquisa a resposta à questão problematizadora acima.
REBEL GOVERNMENT AND CIVILIAN RESISTANCE
Authors: Tafur Villarreal Andrés
Published: May 2022

Cañón de las Hermosas is located in a buffer zone of the Páramos Complex of the National Natural Park of the same name, located on the eastern flank of the Cordillera Central, in the Andean Region of Colombia. Several of the most recurrent symptoms in the diagnosis of civil war in the country were concentrated there: poverty and inequality, state precariousness-weakness, social and territorial control by armed groups, disputes over illegal rents derived from the cultivation and trafficking of illicit drugs (ECHANDÍA CASTILLA, 1996, 2000; APONTE GONZÁLEZ, 2019; OBSERVATORIO DE PAZ Y DERECHOS HUMANOS, 2020a, 2020b). This extensive zone was catalogued as one of the sanctuaries of the FARC guerrillas, which guaranteed security, collected taxes, administered justice and regulated coexistence efficiently and effectively through punishments, fines and executions. This happened, particularly with the protection of the environment, a phenomenon that comes close to what DÁVALOS calls "conservation at gunpoint" (DÁVALOS, 2001; CENTRO DE ESTUDIOS REGIONALES, 2020b).
After the weakening of the guerrilla by the pacification operations during the 2000s, this conservation work was left in the hands of the civilian population, who denounced the destruction of fragile ecosystems due to the militarization of the territory, and particularly, the construction of a hydroelectric dam in the Amoyá river, in the heart of the Hermosas Canyon. In my work I argue that the Observatorio de Derechos Humanos para la Protección del Medio Ambiente and Mesa de la Transparencia del Cañón de las Hermosas can be characterized as civil resistance mechanisms, conceived with the objective of protecting the population and the environment (TAFUR VILLAREAL, 2021). Community preferences are explained by the degree of social cooperation expressed from the mobilization (protest) and organization capacities, which allowed them to join all the autonomous community spaces of the village of Las Hermosas in a social platform for direct and indirect dialogue with institutional and political actors (among which are included the armed, legal and illegal ones).
At the methodological level, the research design and methods integrated fieldwork and archival review with qualitative analysis, and included field interviews, documentary and archival review.
Modelo conceptual para contribuir al desarrollo y crecimiento de spin-off de base tecnológica en la Universidad Nacional Autónoma de Honduras
Authors: Salinas-Martínez Nicolás
Published: May 2022

En la actualidad las universidades desempeñan un rol muy importante en el desarrollo económico y social de los países, fortalecen el espíritu empresarial y son la fuente de muchas empresas emergentes. Este estudio tiene como objetivo desarrollar un modelo conceptual que permita identificar líneas de emprendimiento y una base de emprendedores para impulsar la creación y/o el desarrollo de spin-off dentro de la Universidad Nacional Autónoma de Honduras (UNAH). La investigación se desarrolló tomando los resultados del análisis cienciométrico de la base científica para el emprendimiento tecnológico en Honduras, artículos científicos relacionados a incubadoras/aceleradoras, metodología Lean Startup y desarrollo de spin-off, sitio web de la UNAH, entre otros. Los resultados permitieron generar un modelo conceptual que relaciona la incubadora/aceleradora, base científica de artículos, herramientas de análisis, metodología Lean Startup, líneas de emprendimiento, base de emprendedores, concluyendo finalmente que la UNAH cuenta con componentes necesarios para su consideración y ensayo.
Reverse Time During Current Relay Performance to Support the Protection System Practicum
Authors: Wahyono Wahyono , Sumarno F. Gatot , W Wiwik Purwati , Margana Margana , Suwarti Suwarti , N. Ajie Pribadi
Published: May 2022

—Overcurrent Relay is one of the protection system tools in the electricity network. Overcurrent Relay works based on the increase in fault current that exceeds a certain safety value and a certain period of time. The type of relay that will be used in this test is the IDMT NX203A Overcurrent Relay. The purpose of this test is to get a good practicum module and to prove the inverted time relay characteristic curve according to British Standard BS142. In the test, the tool to be assembled is tested for its work function so that in data collection errors can be avoided while the relay on the module will be given a current setting of 2A; 3A; and 4A with TMS0.05; 0.5; and 1.0 which will be connected to a digital timer so that if the fault current exceeds the setting current, the relay will automatically give a signal and the digital timer will show the time when the current is cut off. The final result is a practicum module where each tool functions under normal working conditions and a graph of time against relay current for setting current 2A, fastest time 0.498s at 9A fault current and 0.05 TMS, longest time 12.991s at 4A TM fault current. . 1.0. Current setting of 3A for the fastest time is 0.572s at fault current of 9A and TM 0.05, for the longest time is 35.854s at fault current of 4A and TM 1.0. Current setting of 4A for the fastest time is 0.708s at fault current of 9A and TM 0.05, for the longest time is 55.979s at fault current of 5A and TM 1.0.
Design of DC Accumulator Charging using Backup Accumulator Based on Inverter and Converter Device
Authors: Marpaung Parlindungan Pandapotan
Published: May 2022

The charging of DC accumulator that
experiences a lack of electric charge energy, usually
utilizes an AC input power from the PLN network. When
the AC input power from the PLN network is unavailable,
a DC power source is used from the backup DC
accumulator as a substitute. The research objective is to
design an internal DC accumulator charging using a
backup DC accumulator equipment based on inverter
and converter equipment. The charging system will use
input power from the backup DC accumulator to replace
the AC input power from the PLN network. The electric
voltage of the internal DC accumulator that is filled
(charged) is the initial condition of V
DC(Acu.Int.)= 8.76 Volts
until it reaches the normal condition of 12.05 Volts with a
capacity of charging current of 5 Ah (Ampere.hours)
absorbs electrical energy of W(Acu.Int.)
 = 16.45 Wh(Watt.hours). The results show that the equipment supply
a DC charger of 13.0 volts and PDC
of 21.32 watts to theinternal DC accumulator. The comparison of W
(Acu.Int.) to PDC produces time charging, t(charging)of 46.29 minutes
Potencial antioxidante e atividade antimicrobiana do extrato hidroetanólico de Ervatamia coronaria (Apocynaceae)
Authors: Barros Raiane Arruda , Sousa Júnior Dárcio Luiz de , Caldas Francisco Rodrigo de Lemos , Mendes Rafael de Carvalho
Published: May 2022

O uso de plantas medicinais é uma prática da medicina popular realizada desde a antiguidade. Ervatamia coronaria é um arbusto nativo da Índia da família Apocynaceae. A crepe-jasmine como é conhecida popularmente, é utilizada como larvicida, laxativa e proteolítica. A pesquisa teve como objetivo avaliar o potencial antioxidante e a atividade antimicrobiana do extrato hidroetanólico a 70% das folhas de E. coronaria. Os testes foram realizados no Laboratório de Microbiologia da Faculdade de Medicina Estácio de Juazeiro do Norte. O teor de fenólicos foi determinado pelo método de Folin-Ciocalteu, onde apresentou 26,15± 1,82 mg de equivalente de ácido gálico/g de extrato seco. O potencial antioxidante foi realizado pelo método do radical 1,1- difenil-2-picrilhidrazil (DPPH), onde o extrato apresentou CI50 32,80± 1,10 µg/mL. A atividade antimicrobiana foi determinada pelo método de microdiluição em caldo, frente as cepas bacterianas Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 9027), Salmonella enterica (ATCC 14028) e Staphylococcus aureus (ATCC 6538), onde a Concentração Inibitória Mínima (CIM) foi ≥ 1024 µg/ mL, apresentando-se clinicamente irrelevante nas concentrações testadas. Dessa forma, este extrato pode vir a ser um candidato a se tornar um fitomedicamento antioxidante, mas não um antibacteriano de origem natural.
Control estricto de la glucemia: una revisión de la literatura
Authors: Ortiz Jonathan Tomaz
Published: May 2022

La diabetes mellitus es una enfermedad de difícil control a nivel mundial. A partir del mejor conocimiento de la fisiopatología de la enfermedad por parte de la medicina moderna, se han propuesto varias formas de controlar la evolución de la patología en cuestión. Como ejemplo, podemos citar un estudio publicado en 1993 por el Diabetes Control and Complications Trial (DCCT) y, posteriormente, en 1998, validado por el United Kingdom Prospective Diabetes Study (UKPDS), que establecía la hemoglobina glucosilada como uno de los principales marcadores de evolución y pronóstico de la enfermedad. Desde la publicación de estos estudios, metas como: control glucémico estricto (correspondiente a metas de hemoglobina glucosilada menor o igual a 6,5 ​​mg/dL), han sido aceptadas por la comunidad médica mundial como referentes en el control y seguimiento de la enfermedad. En ese contexto, el presente artículo tiene como pregunta orientadora: ¿se debe buscar un control glucémico estricto para todos los pacientes? Con el objetivo de averiguar, a través de la revisión de la literatura, si el control glucémico debe ser requerido para todos los pacientes. Por lo tanto, se realizó una revisión bibliográfica de los artículos publicados sobre el tema en cuestión, con el objetivo de centrarse en la prevención cuaternaria y la importancia de la buena práctica clínica colaborada por la medicina basada en la evidencia. Los resultados indican que, en el caso del control estricto de la glucemia, no existe evidencia de beneficios en general en su uso, siendo reportado en la literatura que, en determinadas poblaciones, especialmente en las mayores de 80 años, su uso está ligado a un aumento Efectos adversos y morbilidad causados ​​por la enfermedad.
PENERAPAN THEORY OF PLANNED BEHAVIOR DALAM PEMBERIAN ASI EKSKLUSIF DI KECAMATAN TAROKAN
Authors: Anwar Saiful , Winarti Eko
Published: May 2022

Introduction: The achievement of exclusive breastfeeding in Kediri Regency 2020 is only 13%, in the Tarokan District area there are several villages which are still below the national target of 40%. The mother's role is very dominant in achieving the target of exclusive breastfeeding. This study aims to determine the behavior of mothers in exclusive breastfeeding using the theory of planned behavior. Method: Quantitative research, observational analytic methods, cross-sectional approach. The research location is in the Tarokan District, carried out from 1 to 20 December 2021 using a simple random sampling technique. Independent Variables: Attitude, Subjective Norm, Behavioral Control. Intervening Variable: Intention, Dependent Variable: Behavior using path analysis. Result: Goodness of Fit CMIN = 0.020, probability = 0.888, GFI=1,000, CFI=1,000, NFI=1,000, TLI=1.009, IFI=1.001, RFI=1,000, AGFI=0.999, RMSEA=0.000, PGFI=0.067. Path coefficient of attitude with intention (β=0.754) (p-value=0.000), (CR=14.871). Subjective norm with intention (β=0.130), (p-value=0.000), (CR=3.374). Behavioral control with intention (β=0.126), (p-value=0.000), (CR=3.429). Intention with behavior (β=0,269), (p-value=0.000), (CR=3.176) Attitude with behavior (β=0.637), (p-value=0.000), (CR=9,198). Behavioral control with behavior (β=0.098), (p-value=0.000), (CR=3.292), attitude through intention towards behavior (0.8325) and behavior control over behavior through intention (0.1505). Discussion: The development of research on health behavior needs to be carried out by further researchers so that they can explore in more depth changes in behavior change in order to plan health behavior change programs in order to improve government programs in the health sector
DIGITAL MARKETING STRATEGY OF KARIKSA KEBUNKU DURING THE COVID-19 PANDEMIC WITH A BUSINESS MODEL CANVAS (BMC) APPROACH
Authors: Manalu Doni Sahat Tua , Nurlatifah Sapti , Sarahsati Febrya
Published: May 2022

Kariksa Kebunku adalah salah satu perusahaan dalam bidang budidaya bunga mawar potong yang terletak di Lembang Bandung Barat. Pada umumnya sebelum terjadi pandemi Covid-19 permintaan bunga mawar potong banyak digunakan pada acara-acara pernikahan, dekorasi, wisuda, hari valentine dan beberapa acara lainnya dan puncak dari tingginya permintaan bunga mawar di Kariksa Kebunku adalah bulan Februasi akan tetapi pada saat pandemi Covid-19 usaha bunga mawar di Kariksa Kebunku mengalami penurunan penjualan. Dengan demikian, Kariksa Kebunku perlu memanfaatkan perkembangan teknologi informasi berupa digital marketing dengan merubah sistem pemasaran untuk melakukan promosi dan pemasaran bunga mawar potong dalam rangka menjangkau pasar yang lebih luas dimasa pandemi Covid-19. Salah satu metode analisis yang dapat digunakan untuk pengembangan bisnis adalah pendekatan Business Model Canvas (BMC).  Tujuan  penelitian menganalisis strategi digital marketing yang dapat diterapkan sebagai salah satu alternatif pengembangan dan solusi terhadap permasalahan di Kariksa Kebunku pada masa pandemi Covid-19 dengan pendekatan Business Model Canvas (BMC). Adapun metode pengumpulan data yaitu pemilihan lokasi penelitian dilakukan secara sengaja (purposive) karena Kariksa Kebunku adalah salah satu usaha yang bergerak dalam bidang tanaman mawar dan terdampak pandemi Covid-19. Data yang digunakan adalah jenis data primer dan sekunder. Penentuan strategi pemasaran dilakukan dengan pendekatan Business Model Canvas (BMC). Hasil penelitian diperoleh berdasarkan sembilan elemen BMC yang terdiri dari customer segments, value proposition, channels, customer relationships, revenue streams, key resources, key activities, key partnerships, dan cost structure yang terangkum dalam satu kanvas menunjukkan bahwa penerapan digital marketing mampu meningkatkan pendapatan yang memberikan keuntungan bagi Kariksa Kebunku pada masa pandemi Covid-19.
THE IMPACT OF BROILER FARMING BUSINESS PARTNERSHIP ON PRODUCTION COST AND INCOME IN METRO CITY
Authors: Rosanti Novi , Okta Sari Nia , Endaryanto Teguh
Published: May 2022

Partnership pattern was the pattern of managing broiler chicken business through cooperation with companies that offered many benefits so that most breeders were encouraged to established partnership patterns. But in the implementation of partnerships not always run in accordance with the agreement because there were  some frauds committed by farmers and companies. The risk of frauds made some farmers chose to manage the broiler breed chicken business independently. The difference in implementation between partnership patterns and self-sustaining patterns can have a performance impact on broiler chicken breeders. This study aims to analyze the partnership patterns, analyze the partnership's driving factors and analyze the impact of partnerships on the production and income costs of broiler breed chicken farmers in Metro City. This study was conducted from October 12 to November 30, 2020 located in Metro City. The methods were used in this research were qualitative and quantitative combined methods. The data was collected through a survey by interviewing directly 59 respondents. The result of this research were The pattern of partnerships of broiler breed chicken farmers in Metro City was the plasma core pattern, 2) The driving factors of partnership in broiler chicken breeders were capital availability motivation, market guarantee motivation, price guarantee motivation and high income motivation, 3) Statistically the partnership pattern had an impact on income and labor allocation. The company could improve the services that were felt by farmer tobe lacking, such as the accuracy of providing production facillities and payment of harverts and could provide competitive sell prices to breeders partner.
Profitability of property industries in Indonesia by using firm specific factors and macroeconomic factor
Authors: Cakranegara Pandu Adi
Published: May 2022

Property companies are a growing industry in Indonesia. This trend makes the property industry an economically attractive industry for the investor. Due to that development, this study examines the factors that affect the profitability of property companies. This study's profitability is represented by the Return On Equity ratio chosen because this variable will provide returns to equity investors. The independent variables in this study consist of company-specific variables and macroeconomic variables. The research method used is the multiple linear regression method using secondary data taken from the company's financial statements from 2015 to 2019. The findings of this study are that both company-specific and macroeconomic factors significantly influence the profitability of property companies. Specifically, company-specific factors that have a significant effect on profitability are also affected by macroeconomic factors, such as companies' ability to owe as represented by the ratio of Debt to Equity Ratio. Investors can use the findings from this study to determine which companies are suitable for investment. Meanwhile, from the company side, management can focus on this study's findings to increase the company's profitability.
Battaglie per il riconoscimento dei diritti e rappresentazioni femminili tra la Rivoluzione francese e lo scoppio della Grande Guerra: un possibile itinerario didattico
Authors: Castro Sonia
Published: May 2022

The article gives a brief introduction on methodological issues concerning gender history and, above all, an attempt to integrate women’s history into current classroom practices. The learning activities cover the women’s emancipation process from the French Revolution to the end of the 19th century, focusing on the struggle for political rights, working women or the image of women in different context.
Quand l’histoire du genre est enseignée au cycle 3
Authors: Bruchez-Bérard Aline
Published: May 2022

The teaching of gender history is now considered an essential aspect of the school curriculum. The question arose as to what material to offer teachers, since the tools currently used in the classroom were not designed with this in mind. Two teachers from the canton of Vaud and a group of experts were commissioned to create nine teaching sequences for the different levels of cycle 3. This article first presents the aims of these new resources, and then the articulation and content of these teaching sequences.
Le droit à l’avortement en Suisse: un débat public et médiatique par et pour les femmes (1971-1972)
Authors: De Toro Marina
Published: May 2022

This article presents some results and insights into the place of the abortion right debate in the history of women and feminism in Switzerland. Between 1971 and 1972, the aim is to highlight the consequences of gendered family policy on the one hand, and the feminist stakes of the struggle for free abortion and the liberation of women’s voices on the other. Shortly after the introduction of women’s suffrage, the public debate on abortion rapidly invaded the media space, which we will examine through a few audiovisual and printed sources.
Komárom et Komárno: ville divisée – commerce de détail transfrontalier
Authors: T. Sikos Tamás
Published: May 2022

Avant le changement de régime de 1989, les disparités économiques entre les deux côtés de la frontière slovaquo-hongroise étaient importantes. Elles étaient particulièrement frappantes dans le cas des villes de Komárom (en Hongrie) et Komárno/Révkomárom (en Slovaquie) qui avaient été brutalement divisées par la frontière hongro-tchécoslovaque en 1920. Après une séparation de près de sept décennies, les conditions politiques et économiques sont à nouveau réunies pour un développement urbain coordonné et commun. Le rapprochement entre les deux villes s’est matérialisé sous plusieurs formes : croissance du tourisme traditionnel et d’achat, croissance de la mobilité quotidienne transfrontalière, renouvellement des relations personnelles, etc. Cet article examine plus spécifiquement les habitudes de consommation des habitants dans un contexte transfrontalier marqué par la restructuration du tissu commercial.
Les jardins partagés franciliens : un espace d’entre-soi
Authors: Mestdagh Léa
Published: May 2022

Le discours institutionnel, ainsi que celui des jardiniers eux-mêmes, décrit les jardins partagés comme des outils de cohésion sociale et de participation à la vie de quartier. Cependant, on remarque une forte homogénéité, en particulier sociale, des profils de jardiniers. L’article, issu d’une enquête par questionnaire et observation participante, décrit cette homogénéité ainsi que la façon dont les jardiniers trouvent une cohérence dans l’opposition entre leurs représentations et la réalité de leurs pratiques.
Militer pour la décroissance : du discours militant à la réappropriation de l’espace local
Authors: Pailloux Anne-Laure , Mège Arnaud
Published: May 2022

Au cœur des logiques militantes de l’engagement pour la décroissance se dessine un principe central: la relocalisation. Cette injonction oriente les pratiques quotidiennes – consommer local – et les activités militantes – participer à des collectifs dans son espace de vie. Cet article se propose de rendre compte d’un engagement dont la proximité constitue une norme structurante, encourageant ainsi de nombreuses initiatives localement ancrées tout en produisant un entre-soi socialement situé.
La structuration du domaine scientifique du développement territorial et l’importance à accorder aux revues internationales
Authors: Halleux Jean-Marie
Published: May 2022

Cet article interroge les orientations à donner au champ du développement territorial en matière de publication et de valorisation des recherches. Il débute en présentant le contexte actuel de la diffusion des résultats de la recherche dans ce domaine scientifique. Il se focalise ensuite sur le sujet des revues internationales anglo-saxonnes, en analysant l’opportunité pour les chercheurs francophones d’y publier davantage. Il ressort de cette analyse qu’il est souhaitable que les chercheurs francophones publient davantage en anglais. Pour autant, il faudra absolument éviter les deux écueils consistant à délaisser les publications en français et à négliger l’objectif prioritaire de la contribution à la réussite des politiques territoriales.
Gérer les proximités et franchir les distances. L’agencement des proximités dans la mobilité quotidienne périurbaine
Authors: Fourny Marie-Christine , Cailly Laurent
Published: May 2022

L’analyse du vécu des navettes périurbaines permet de montrer une diversité des proximités engagées dans la gestion de la distance spatiale : mise en proximité des lieux de pratique par le vécu de l’espace-temps du déplacement, proximités liées à la médiation technologique, relations sociales de coprésence construites dans la mobilité ou activées sur les lieux de résidence et de travail pour l’organiser. L’agencement de ces formes conduit à défonctionnariser le déplacement et à le transformer en espace-temps « habité », inscrit dans une continuité avec les espaces qu’il relie.
Être piéton à Salvador de Bahia et Caracas : une proximité fragilisée ?
Authors: Fiori Sandra , Thomas Rachel
Published: May 2022

Cet article s’intéresse à l’usage piéton de la ville à partir de l’expérience d’espaces publics latino-américains qui, conflictuels, segmentés socialement, travaillés par un arrière-plan sécuritaire et soumis à de forts enjeux de réaménagement, fragilisent le partage de la rue. C’est en rendant compte des formes d’expression sensibles par lesquelles le corps en marche y engage des manières d’être ensemble que le thème de la proximité est alors ici abordé.
L’objectivation des impacts paysagers des projets éoliens : solution ou source de conflits ?
Authors: Kodjovi Marie-Joëlle , Bomberger Pierre-Henri , Gerber Jean-David
Published: May 2022

Cet article questionne les modalités de traitement de la question paysagère dans les projets éoliens. À travers l’étude du cas vaudois, les conceptions institutionnelles de cet enjeu sont confrontées aux représentations sociales des usagers des territoires. L’analyse montre l’incapacité des procédures actuelles à dépasser une approche ressourcielle du paysage, ce qui génère de multiples conflits territoriaux autour de la prise en compte des relations hommes-milieux dans ces projets énergétiques.
Tessin et urbanisation néolibérale: évolution des discours en matière d’aménagement
Authors: Cometta Mosè
Published: May 2022

Cet article étudie l’évolution discursive de l’aménagement du territoire au Tessin (Suisse). L’analyse de l’évolution des discours urbanistiques tessinois – les plans directeurs de 1990 et 2009 – et la compréhension du Tessin qui les sous-tend montrent une transition des institutions du keynésianisme au néolibéralisme. Le passage d’un modèle de centralisation décentralisée à un modèle de spécialisation fonctionnelle montre la transformation des objectifs de développement par les institutions. Cela permet de mieux comprendre les problèmes et les tensions des territoires périphériques
The Response Time of Trauma and non Trauma Patients Handling in Emergency Room Surabaya
Authors: Setiawati Yuani , Kusumaningtyas Maya Hapsari , D’Arqom Annete
Published: May 2022

Background: Emergency room is one of the unit services in hospitals that provide first services in patients with threat of disability or even death. Emergency room is a service unit in hospital with 24 service hours for 7 days in a week. The high risk and working hours in the emergency room requires the medical personnel that have a good response times in triage room.
Objective: To compare response time of medical personnel when handling trauma and non trauma patients in the emergency room.
Method: A non-experimental, quantitative research methods using analytic observational. The population of this study was patient in emergency room Soetomo hospital Surabaya. The amount of the sample was 244 which divided into 41 trauma case and 203 non trauma case.
Result: Response time of patients with trauma injuries that include quick category (< 5 minutes) amounted to 35 patients and 6 patients in slow category (> 5 minutes) with average response times of trauma patients is 6.244 minutes. Response time of patients with non trauma injuries that include quick category (< 5 minutes) amounted to 161 patients and 42 patients in slow category (>5 minutes) with average response times of non trauma patients is 3.722 minutes. The p value response times of medical personnel in dealing with trauma and non-trauma patients is 0.374 (> 0.05) which means there is no difference in response times from medical personnel in handling trauma and non-trauma patients.
Conclusion: There was no difference in the response time of medical personnel in trauma and non-traumatic patients handling (p>0,05). Overall, it was found that the average emergency room’s response time at Soetomo hospital was 4.15 minutes, still meeting the applicable standards.
Study and Numerical Simulation of Negative and Positive Corona Discharge: A Review
Authors: Asipuela Angel , Iváncsy Tamás
Published: May 2022

Two models to describe the phenomenon of corona discharge are presented: the first is known as the plasma model which with plasma chemistry defines the volumetric and surface reactions among charge carriers such as electrons, positive, and negative ions. This model uses Poisson's equation and a formulation of the space-charge density to calculate the electric field necessary to solve the species transport equations. Besides, only the plasma model determines the density of the charge carriers. The second is a simplified model which describes the corona discharge in terms of current conservation coupled with Poisson's equation. This model does not have any connection with the attributes of plasma chemistry. Both models propose solutions for the electric potential and space charge density distribution from the corona electrode to the ground electrode.
Invasive plant species in the area of the significant landscape Gajna
Authors: Antunović Slavica , Živković Josipa , Čuljak Alen , Benković Robert , Mirosavljević Krunoslav , Štefanić Edita , Božić-Ostojić Ljiljana
Published: May 2022

Invazivne biljne vrste su naturalizirane strane, namjerno ili nenamjerno unesene biljke na područje Republike Hrvatske. Prema podatcima Svjetske udruge za zaštitu prirode one predstavljaju drugi glavni uzrok ugroženosti autohtonih vrsta, samim tim i bioraznolikosti. U Hrvatskoj je registrirano oko 617 alohtonih vrsta od čega je 70 invazivnih. Istočno od Slavonskog Broda uz rijeku Savu nalazi se 1500 ha poplavnog područja od čega se na oko 280 ha prostire tipični slavonski naplavni pašnjak Gajna. Brodsko ekološko društvo je podnijelo zahtjev, a Republički zavod za zaštitu prirode prijedlog te je 14.09.1990. godine odlukom Skupštine općine Slavonski Brod, Gajna dobila status značajnog krajobraza. U sastavu bogate i raznolike flore ovog područja nalaze se i alohtone invazivne biljke. Cilj rada je bio tijekom vegetacijske sezone 2019. godine determinirati ih, navesti načine njihovog rasprostranjivanja i mogućnosti suzbijanja. Utvrđene su sljedeće invazivne vrste: ambrozija, amorfa, cigansko perje, kanadska hudoljetnica, jednogodišnja krasolika, perzijska čestoslavica i obalna dikica. Tarupiranjem i ispašom podolskim govedima, uspjelo se suzbiti amorfu koja je do prije nekoliko godina predstavljala veliki problem nakon, čega je počela rasti i razvijati se prirodna flora što do tada nije bilo moguće. Trenutno je raširena i u velikom broju prisutna obalna dikica čiji se plodovi lako rasprostranjuju, a kako je Gajna naplavni prisavski pašnjak, sjemenke se još dodatno šire i vodom.