bluuebunny/crossref_metadata_2025 huggingface dataset:
Une plateforme pour favoriser l’apprenance des jeunes adultes : le cas du MOOC Gestion de projet et sa communauté de pratique
Authors: Oliveri Nicolas , Traoré Jamal
Published: May 2023

Cet article évalue, à partir de l’étude approfondie d’un Mooc (massive open online courses) de gestion de projet, la capacité d’un tel dispositif à favoriser l’activité d’apprentissage dans une visée de montée en compétences de publics variés, principalement les jeunes adultes, engagés au sein d’une communauté de pratique (CdP) dans le sens d’Étienne Wenger (Wenger et al., 2002). Le cadre d’analyse retenu (modèle IMAIP) tend à évaluer le rapport au savoir dans une telle communauté par l’observation de ses éléments structurants, tout en passant au crible le dispositif central de cette communauté qu’est le MOOC « Gestion de projet » (MOOC GdP). Cette étude met en exergue un changement d’attitude face au savoir dans une société de connaissance enjoignant à améliorer l’employabilité des jeunes adultes à travers une attitude proactive et agile dans sa gestion des compétences. Nous montrons par une approche compréhensive que le dispositif MOOC GdP pourrait constituer un jalon favorisant une attitude proactive couplée à des pratiques collectives et un apprentissage tout au long de la vie (ATLV), condition sine qua none d’acquisition de la méta-compétence de « l’apprendre à apprendre », proche du concept de « deutéro-apprentissage » (Bateson, 1972).
Sémiologie des toilettes
Authors: Jullier Laurent
Published: May 2023

Cet article traite de la signalétique indiquant aux usagers de toilettes publiques laquelle des deux portes ils doivent pousser, « Hommes » ou « Femmes ». Les pictogrammes, à cet endroit, s’efforcent de mobiliser des universaux, en l’occurrence des signes visuels de distinction sexuelle saisissables sans compétences particulières par le plus grand nombre possible de personnes. Mais les vrais universaux sont rares. L’article passe en revue les dénotations et connotations des pictogrammes les plus courants, en utilisant quelques outils heuristiques venus de la sémiologie, des études de genre, de la psychologie et de la sociologie interactionniste.
Métiers et numérique : étude d’une évolution dynamique
Authors: Djambian Caroline
Published: May 2023

Les notions intrinsèquement liées de métier, qualification et compétence ont connu des révolutions successives au cours de notre histoire. Toujours remises au-devant de la scène lors des périodes de grands changements qui engendrent des replis identitaires des organisations, elles connaissent un nouvel avènement avec la vague numérique. Nous tentons ici de retracer leur évolution dynamique alliée plus que jamais à celle des innovations technologiques, sous l’angle des Sciences de l’Information-Communication. Nous verrons que la médiation des métiers et modes de travail par les Technologies de l’Information Communication (TIC) va croissante et touche tous les secteurs d’activité, de sorte que certains y voient une nouvelle économie. Mais les TIC ont-elles l’impact qu’on leur prête ? N’accompagnent-elles pas les évolutions dans leur continuité, plus qu’elles ne les provoquent ? N’engendrent-elles pas des glissements des métiers et compétences, plus qu’elles ne créent ou tuent des professions ?
Credibility Perceptions of Online Political News Among Bangladeshi Millennials Residing in the Capital
Authors: Ullah Mohammad Nur , Hossain Sadia Anjum , Tazin Raiyana , Biswas Bikram
Published: May 2023

With the expansion of political technology, newsrooms are now escaping borders by introducing cloud-based news broadcasting platforms right to people's fingertips, and concerns regarding the legitimacy of these internet political news sources are simultaneously emerging. Since the millennials had the opportunity to get the essence of both the mainstream and the digital media outlets, the primary objective of this study is to investigate and examine the perceptions of Bangladeshi millennials regarding the credibility of digital political news coverage and the content they convey. A structured questionnaire survey been used for this study as primary data sources. The study found that, although the mainstream dynamic political news media outlets have wider-spread popularity, the millennials of Bangladesh find that the newly emerged online mediums are more credible for receiving political news.
Review of Translation and Contemporary Art: Transdisciplinary Encounters
Authors: Wang Bingrun , Peng Keming , Wu Yixuan
Published: May 2023

As a well-established field, translation studies (TS) has acquired significance since the late 20th century, with a proliferation of TS journals, conferences, and books over the last three decades. The result of such expansion is diversification, leading to multiple interpretations of the term “translation studies.” Since the cultural turn in TS was proposed in 1990, the notion of what translation involves has been expanded. An increasing number of translation researchers are inviting us to expand the object of the field. The book represents the most recent discovery in cross-boundary translation studies. It is organized into three sections, namely “Translating in a Visual Age: Transdisciplinary Routes,” “The Artistranslator's Gaze,” and “Translating With Art.”
Simulation of Liquefied Natural Gas (LNG) Fluid Flow on Ambient Air Vaporizer
Authors: Mohd Nor Mohd Asri , Mohamad Razki Muhammad Ammar Imran , Manan Nor Fazli Adull
Published: May 2023

An ambient air vaporizer (AAV) is an industrial heat exchanger equipment used in the vaporization process of liquefied gases before supplying to consumers. AAV utilizes the simple heat transfer principle that uses surrounding ambient air to vaporize the liquefied gases. Liquefied Natural Gas (LNG) is one of the liquefied gases commonly associated with AAV applications. Due to a significant temperature difference between cryogenic fluid of LNG and ambient air, frost formation is inevitable to reduce the heat transfer rate. Fins geometry contributes a substantial impact on the performance of AAV and is the main element of heat transfer for AAV. This study aims to design a model of an AAV with a star 6-finned tube vaporizer with hexagon shape and to simulate the fluid flow on the vaporizer model to demonstrate the LNG vaporization process. The hexagon vaporizer model is designed using Solidworks, and heat transfer model is simulated using computational fluid dynamics (CFD) tool, Ansys Fluent solver. Parameters such as fin geometry, LNG flowrate and wind speed were referred from previous studies. Methane and air are assumed as working fluids inside and outside of the vaporizer model. Wind temperatures of 300K (27°C), 303K (30°C), and 306K (33°C) are utilized in the simulation process based on geometrical weather in Malaysia. In the simulation model, methane entered from the bottom of the tube, while air entered horizontally at x-direction from the right side. The temperature contour shows that as the temperature of methane that flowed inside the tube increased as it entered the tube, the air temperature reduced as it entered and flowed passes through the finned tube. The analysis from the simulation model shows that higher air temperature with substantial wind speed can increase the outlet temperature of methane (LNG), thus improving the performance of AAV.
Effect of Ga Substitution at Mn Site on Electroresistance Behavior in Monovalent Doped La0.85Ag0.15Mn1-xGaxO3 Manganites
Authors: Ibrahim Norazila , Rusop Nur Azeni Mohamad , Rajmi Rozilah
Published: May 2023

The effects of Ga substitution at Mn site on electroresistance behaviour of La0.85Ag0.15MnO3 compound prepared by solid-state reaction method were investigated. X-ray diffraction (XRD) measurement were recorded at room temperature and refined by employing Rietveld techniques. Ferromagnetic to paramagnetic transitions behaviour have been observed from ac susceptibility results. Resistivity-temperature curve with different applied currents of 1 mA and 5 mA showed metal-insulator, MI transition temperature, TMI decreased with increased of the applied currents. The increased in applied current caused the maximum resistivity around TMI to be decreased for both samples indicated increased in charge carrier density which resulting in drop of resistivity, hence, enhanced double exchange mechanism. The electroresistance (ER) effects have been investigated. The result showed that the ER effect increases when Ga is substituted.
Properties of Pervious Concrete Made with Ferrochrome Slag as a Coarse Aggregate
Authors: Al-Jabri Khalifa , Abosohel Kazi Md Abu
Published: May 2023

Ferrochrome slag (FCS) is produced during the production of ferrochrome alloy, which is an essential component of stainless steel. FCS has favorable physical and chemical properties for use as an aggregate in place of natural aggregate in the production of conventional and pervious concrete. Previous studies reported that the mechanical properties of concrete are enhanced when FCS is used in place of natural aggregates. This study evaluated the performance of pervious concrete containing FCS aggregates to replace the natural aggregates (NA) in various percentages (0%, 25%, 50%, 75% and 100% by weight). The effect of FCS replacement ratios on the mechanical properties (compressive strength, flexural strength, and split tensile strength), water permeability in terms of infiltration rate and density of the pervious concrete were determined. The results showed that the coefficient of water permeability increases with the increase of ferrochrome slag content. However, the compressive strength and density are reduced due to the increase of the porosity of the concrete. The optimum replacement percentage of natural aggregate with FCS aggregate was found to be 75%. The study concluded that it is possible to produce sustainable pervious concrete by using waste ferrochrome slag.
Coconut Shell Ash (CSA) as the Stabilizer for Soft Soil Treatment
Authors: Rahman Abdul Samad Abdul , Sidek Norbaya , Hasim Sulaiman , Ahmad Juhaizad , Fazlan Mohd Ikmal Mohd , Mohamad Nur Syazwana
Published: May 2023

Soft soil consists of inherent properties where it is unstable in geotechnical condition with low shear strength. The present of soft soil is one of the problematic ground conditions that can pose great challenges in the related field. Moreover, soft soil is not suitable for being used in the construction of highways and buildings due to its undesirable characteristics such as high-water content, low shear strength, low bearing capacity and low permeability. Thus, soil improvement will be crucial in future geotechnical practice for designing structures in weak soil. The aim of this study is to investigate the effectiveness of the use of coconut shell ash (CSA) as an additive material to improve the strength of the soft soil. Preliminary tests were carried out on the soft soil sample for identification and classification purposes. Then, engineering tests were carried out such as compaction tests to determine the optimum moisture content (OMC) and maximum dry density (MDD), Un-confined Compression Test (UCT) to assess the unconfined compressive strength of the soft soil when mixed with 0, 5, 10, and 15% of CSA. Finally, this study resume that the coconut shell ash can act as a stabilizer that will lower the cost of treatment and will benefit the environment.
Strategie per lâ€™attuazione delle Cure Fondamentali: una revisione della letteratura
Authors: Durante Lisa , Mazzariol Elisa , Buffon Marialuisa
Published: May 2023

Introduzione: Recentemente si Ã¨ assistito ad una fervente spinta alla riflessione nella letteratura infermieristica riguardo le cure fondamentali, motivata dal riconsiderare valori importanti per la professione infermieristica quali compassione e dedizione, e da questioni organizzative come la carenza di personale o la collaborazione con altre figure professionali. Lo scopo di questa revisione Ã¨ individuare quali sono le possibili strategie al fine di garantire alla persona assistita lâ€™erogazione di cure fondamentali. Materiali e metodi: La letteratura Ã¨ stata ricercata nelle banche dati PubMed e CINAHL. Sono stati reperiti 251 articoli e selezionati, sulla base dei quesiti di ricerca, 32 articoli full-text sottoposti ad analisi. Di questi, 9 articoli sono stati esclusi perchÃ© non pertinenti. Risultati: La letteratura fa emerge che gli ostacoli allâ€™applicazione delle cure fondamentali riguardano prevalentemente fattori organizzativi (tempo, carico di lavoro, influenza dei leader) caratteristiche individuali degli infermieri (atteggiamenti, comportamenti, e fattori interpersonali (capacitÃ  di relazionarsi). In letteratura vengono proposte strategie per applicare le cure fondamentali, ad esempio lâ€™Intentional Rounding, che prevede di effettuare dei giri di controllo degli assistiti programmati ad orario o il metodo AMG (Amalgamation of Marginal Gains) attraverso il quale sarebbe possibile ottenere un miglioramento dellâ€™assistenza erogata a partire dallâ€™attenzione per i dettagli. Discussione: CiÃ² che rende possibile unâ€™assistenza di qualitÃ  non Ã¨ tanto un cambiamento radicale nellâ€™organizzazione generale, quanto il fatto che ogni singolo professionista adotti un approccio che dia la stessa importanza ad ogni gesto che va a compiere. Un approccio in cui le percezioni, le necessitÃ  e le esperienze della persona vengono sistematicamente considerate permette di identificare la modalitÃ  piÃ¹ corretta per rispondere pienamente ai bisogni dellâ€™assistito Conclusioni: Adottare un approccio centrato sulla persona permette di accogliere e soddisfare pienamente i bisogni dellâ€™assistito, il che comporta unâ€™attuazione completa delle cure infermieristiche fondamentali. Tuttavia, gli spunti pratici per lâ€™implementazione di questo approccio risultano limitati. Parole chiave: cure fondamentali, infermieristica, cura, bisogni dellâ€™assistito.
Il carico di lavoro infermieristico in una terapia intensiva COVID-free: uno studio retrospettivo descrittivo
Authors: Zoppini Laura , Scala Cristina , Gulizia Domenico , Cipolla Cristiana Alessandra , Alberti Beatrice Maria Benedetta , Stellabotte Michele , Pagani Silvano , Ravanelli Manuel Giuseppe , Costa Davide , Baciu Camelia Adriana , Barlo Gaia , Porro Barbara , Di Paola Antonio , Anzaldi Erika , Gubertini Alessandro , Zanoni Claudia
Published: May 2023

Sin dall'inizio della pandemia da SARS-COV2 le terapie intensive italiane sono state messe a dura prova ed hanno dovuto ripensare alle proprie dotazioni di personale e mezzi. Il carico di lavoro infermieristico nelle Terapie Intensive dedicate a pazienti COVID-19 positivi ha subito grosse modifiche rispetto alla situazione precedente all'emergenza. Nessuno studio è stato fin ora condotto riguardo il carico di lavoro infermieristico nelle Terapie Intensive COVID-free durante il periodo di esordio della pandemia da SARS COV-2. L'obiettivo di questo lavoro è  stato quindi quello di descrivere la variazione del carico di lavoro infermieristico in una Terapia Intensiva COVID-free di un ospedale pubblico milanese.
Il vissuto degli infermieri durante le chiamate di emergenza effettuate da bambini: uno studio fenomenologico nelle centrali operative 118 del Veneto (Italia)
Authors: Fanti Michela , Carta Antonello
Published: May 2023

L'infermiere della Centrale Operativa 118 (COP 118) del Sistema Urgenza Emergenza Medica (S.U.E.M.) durante la chiamata di emergenza deve identificare la condizione critica mediante l'utilizzo di un metodo di triage telefonico che permetta di effettuare il dispatch, inviando di conseguenza sul posto il mezzo e lo staff più appropriati. Gli outcomes risultano essere migliori se l'infermiere riesce a riconoscere precocemente i sintomi del paziente: risulta essere fondamentale la comunicazione telefonica con l'interlocutore, soprattutto quando è un bambino. L'obiettivo dello studio è conoscere i meccanismi messi in atto dai professionisti nel momento in cui sono entrati in contatto telefonico con bambini che assistevano a situazioni di emergenza.
Studio esplorativo retrospettivo sui ricoveri dei neonati in una Terapia Intensiva Neonatale italiana durante la pandemia da COVID-19
Authors: Rossi Silvia , Serveli Simona , Scelsi Silvia
Published: May 2023

La nascita pretermine (<37 settimane di età gestazionale) è una delle principali cause di morte infantile. Alcuni studi internazionali recenti dimostrano un'associazione tra le misure di lockdown adottate negli ultimi anni e una riduzione nei parti pretermine.
Il vissuto degli Infermieri di Area Critica durante la pandemia da COVID-19: uno studio qualitativo
Authors: Dignani Lucia , Guarinoni Milena Giovanna , Calisse Valentina , Girotti Susi , Toccaceli Andrea
Published: May 2023

Introduzione: La pandemia da COVID-19 ha determinato un forte impatto sui sistemi sanitari di tutto il mondo. Gli operatori sanitari, e gli Infermieri in particolare, hanno dovuto affrontare importanti sfide cliniche ed organizzative, mettendo a rischio la propria incolumità.Risulta quindi interessante comprendere l'esperienza dei sanitari che lavorano in prima linea nella gestione dell'emergenza sanitaria.Obiettivi: L'obiettivo dello studio era di esplorare il vissuto degli Infermieri di area critica impiegati nell'assistenza a pazienti affetti da COVID-19.Materiali e metodi: E' stato condotto uno studio qualitativo fenomenologico descrittivo. Sono stati arruolati gli Infermieri di Pronto Soccorso e Terapia Intensiva di un DEA di 2° livello impegnati nell'assistenza a pazienti con SARS-CoV2, nel periodo aprile-maggio 2020. La raccolta dati è avvenuta attraverso interviste non strutturate, audio registrate, face-to-face. Le interviste sono state trascritte e analizzate.Risultati: Sono state condotte 12 interviste in cui sono emersi 6 temi e 17 sottocategorie. Le aree tematiche evidenziate erano: impatto emotivo, rapporto con i pazienti, ambiente lavorativo, Dispositivi di Protezione Individuale, ambiente familiare, adattamento.Discussione: I temi emersi hanno evidenziato l'esperienza vissuta dagli Infermieri, suggerendo che la pandemia ha determinato un forte impatto sia sulla sfera lavorativa che su quella personale dei professionisti, in linea con la letteratura internazionale.Conclusioni: Lo studio ha fornito importanti informazioni sull'impatto emotivo e lavorativo che la pandemia ha avuto sugli Infermieri. Comprendere l'esperienza degli operatori di prima linea è essenziale per mettere in atto strategie efficaci per ridurre lo stress, il burnout e migliorare la qualità assistenziale.Parole Chiave: epidemia da coronavirus, COVID-19, esperienza, ricerca qualitativa.
Strategie per la corretta previsione dei tempi operatori allo scopo di aumentare l'efficienza in sala operatoria: uno studio osservazionale retrospettivo
Authors: Laus Gennaro
Published: May 2023

Introduzione: La conoscenza delle tempistiche di sala operatoria può portare a una pianificazione accurata consentendo di individuare i punti deboli e le criticità, potendo poi concentrare le forze in questi punti allo scopo di correggerli. La pianificazione aggiunge valore a un'organizzazione ma deve essere garantita da indicatori di performance dei tempi operatori. Tali indicatori permettono di analizzare il processo operatorio valutando le performance. L'obiettivo che si prefigge lo studio è di conoscere le tempistiche di sala operatoria ottenendo una pianificazione giornaliera migliore.Materiali e Metodi: E' stato condotto uno studio osservazionale retrospettivo dal 1 Novembre 2020 al 30 Aprile 2021 che coinvolge le cinque branche chirurgiche dell'IRCCS CROB al fine di analizzare e monitorare i tempi operatori degli interventi chirurgici, proponendo uno strumento di supporto. Lo studio utilizza tre indicatori: Tempo pre operatorio (T1), Tempo chirurgico (T2) e Tempo post operatorio (T3).Risultati: Dall'analisi dei dati rilevati emerge che gli interventi validi sono stati 209. Il tempo pre-operatorio si attesta sui 58,55 min, il tempo post-operatorio sui 36,84 min e il tempo chirurgico sui 99,76 min. I tempi pre e post operatori risultano essere i principali tempi su cui ottenere un margine di miglioramento e quindi i primi su cui agire.Discussione: L'adozione di uno strumento di consultazione con i tempi medi degli interventi può aiutare il personale nella stima di durata e occupazione delle sale. Lo studio presentato è volto a migliorare le prestazioni della sala operatoria in termini di qualità  delle cure, efficacia ed efficienza, ottenendo una pianificazione giornaliera migliore.Conclusioni: E' auspicabile un monitoraggio continuo dei tempi operatori con revisioni periodiche.
Ecografia polmonare a cura dell’infermiere in Terapia Intensiva per monitorare i pazienti con ARDS: BLUE Vs. LUS score
Authors: Piani Tommaso , Rebbelato Alice , Fabris Stefano , Vetrugno Luigi
Published: May 2023

Il monitoraggio dei pazienti con insufficienza respiratoria utilizzando SpO2 da solo non esprime la gravità della malattia rispetto alla malattia polmonare. Attraverso il punteggio dell'ecografia polmonare (LUS), è forse meglio valutare il punteggio di aerazione del paziente e seguirlo nel tempo.
The Role of Dyslipidemia in Atherogenesis in Peritoneal Dialysis Patients
Authors: Rebić Damir , Begić Edin , Aziri Buena , Džubur Alen , Gogić Ena , Durak-Nalbantić Azra , Hamzić-Mehmedbašić Aida , Hasanspahić Senad , Granov Nermir
Published: May 2023

Background:

To evaluate atherosclerotic changes in carotid arteries (CCA) in uremic patients before and after 18 months of continuous ambulatory peritoneal dialysis (CAPD) treatment, and to evaluate the impact of dyslipidemia and CAPD treatment on vascular remodeling.

Materials and Methods:

We conducted a longitudinal, prospective study during 2020 and 2021 at the Clinic for Nephrology, Clinical Center University of Sarajevo. Patients with end-stage renal disease were included and were followed during 18 months of CAPD treatment. All patients were treated using commercially prepared biocompatible balanced dialysis solutions. Carotid intima-media thickness (IMT) and atherosclerotic plaques on the common carotid artery (CCA) were measured by echotomography.

Results:

A total of 50 patients were included and were followed during 18 months of CAPD treatment. Lipid values in the serum of patients with CAPD were significantly lower after 18 months of CAPD treatment compared to the values before treatment, while the value of high-density lipoprotein (HDL) was significantly increased after 18 months of CAPD treatment. The values of IMT and the diameter of the CCA compared to the basal values were significantly lower (P < 0.001).

Conclusion:

We demonstrated significantly lower lipid values and higher HDL levels following CAPD treatment. Correct selection of the targeted pharmacological intervention can substantially impact the regression of vascular changes in patients on peritoneal dialysis.
The Evaluation of HERV-K np9, rec, gag Expression in Isolated Human Peripheral Blood Mononuclear Cell (PBMC) of Gastric and Colon Cancer
Authors: Tavakolian Shaian , Iranshahi Majid , Faghihloo Ebrahim
Published: May 2023

Background:

In the current age of diagnostic approaches in cancer, countless efforts have been allocated to identify novel and efficient biomarkers to detect cancer in its early stages. We focused on evaluating the correlation between the progression of gastrointestinal cancer, a leading cause of cancer death worldwide, and human endogenous retrovirus (HERV).

Materials and Methods:

In this study, we conducted a study on the peripheral blood mononuclear cells (PBMC) gathered from gastric and colon cancer patients. We focused on HERV-K rec, np9, gag expression analysis by quantitative real-time PCR, after extraction of RNA and synthesizing cDNA.

Results:

Unlike np9 whose expression increased significantly in the colon and gastric cancers, the mRNA level of the rec gene declined in both cancers. Moreover, our data illustrated that the over-expression of the gag gene was only observed in colon cancerous cells rather than gastric malignancy.

Conclusions:

Overall, given the correlation between the expression level of HERV-associated genes and gastrointestinal cancer, our study suggests that these genes could be considered beneficial markers for cancer diagnosis. However, researchers should conduct studies in future articles on whether these genes can be employed as biomarkers in gastrointestinal cancer.
Screening of Endometrial Cancer Related to Lynch Syndrome in China by Suction Curettage-Based Cytology and Histology: A Retrospective Study
Authors: Yang Bo , Guo Huiqin , Shen Guqun
Published: May 2023

Objective:

To explore the feasibility of sampling Chinese patients by suction curettage for cytological and histological screening of endometrial cancer related to Lynch syndrome.

Methods:

This retrospective study enrolled patients who underwent endometrial biopsy at our hospital between May 2018 and January 2019. Endometrial sampling (cytological and micro-histological specimens) was conducted by suction curettage. The gold standard for diagnosis was traditional sharp dilation and curettage (D&C). The sensitivity, specificity, and diagnostic accuracy of cytology, micro-histology, and the combination of cytology and micro-histology were calculated. Additionally, receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic efficiency of three screening methods. Mismatch repair proteins were further detected using immunohistochemistry (IHC) in endometrial cancer.

Results:

This retrospective finally enrolled 100 patients, which satisfactory samples were obtained from 96 patients for liquid-based cytology and 93 patients for microtissue histology. The concordance rates with D&C, sensitivity, and specificity were 94.8%, 76.9%, and 97.5% for liquid-based cytology, 96.8%, 84.6%, and 98.8% for microtissue histology, and 99.0%, 92.3%, and 100.0% for liquid-based cytology and microtissue histology combined, respectively. The AUC of ROC curves in liquid-based cytology, microtissue histology, and the combined methods for diagnostic ability were 0.873, 0.917, and 0.962, respectively. Absence rates of MLHl, MSH2, MSH6, and PMS2 proteins were 15.3% (2/13), 0% (0/13), 7.7% (1/13), and 15.3% (2/13) in the 13 endometrial cancer samples.

Conclusion:

Liquid-based cytology and microtissue histology samples from suction curettage combined IHC are useful for endometrial cancer screening.
Diagnostic Value of Preparing Additional Liquid-Based Cytology Slides and Cell Blocks from Residue Material in Thyroid fine Needle Aspiration
Authors: Erdogan-Durmus Senay , Erdem Zeynep B. , Yulek Ozden
Published: May 2023

Background and Aims:

After liquid-based cytology (LBC) technique developed for cervical cytology, it has been used for nongynecological samples and has been very successful. It offers having extra slides of the samples for further examination and ancillary tests. Moreover, cell blocks can be formed from the residue material. The study aimed to evaluate the importance of preparing a second LBC slide or a cell block from the residue material of thyroid fine needle aspiration (FNA) samples to reach a definitive diagnosis in cases diagnosed as nondiagnostic (ND) after the first slide.

Material and Methods:

Seventy five cases diagnosed as ND after the first slide were included in study. For 50 cases, the second LBC slides were prepared (LBC group); for 25 cases, cell block was performed from residue material (CB group). Two groups were compared in terms of reaching a definitive diagnosis.

Results:

At the end of secondary procedures, a definitive diagnosis was reached in a total of 24 cases (32%). Twenty of 50 cases (40%) in LBC group reached a definitive diagnosis while four cases (16%) in the CB group reached a definitive diagnosis. Achieving a definitive diagnosis was found statistically higher in the LBC group in which the second slide was formed compared to the CB group (P =0.036).

Conclusion:

Preparing a second slide with LBC method is more purposive than preparing a cell block from the residue material of thyroid FNA samples. Reducing the percentage of ND cases will protect patients from complications and morbidity that may arise from repeated FNA.
Quality and Performance of Papanicolaou Test using the Clinical and Laboratory Standards Institute (CLSI) EP12-A2 Guidelines: A Single-Center Study in Peru
Authors: Moya-Salazar Jeel , Huarcaya Jennifer , Vazquéz Diana , Rojas-Zumaran Víctor , Contreras-Pulache Hans
Published: May 2023

Context:

Quality assurance in cervical cytology is based on the cyto-histological correlation that is performed in several countries even without standardized protocols.

Aims:

To evaluate the quality of the Pap smear with the Clinical and Laboratory Standards Institute (CLSI) EP12-A2 guideline in a Peruvian hospital.

Settings and Design:

This prospective study was carried out at tertiary care national hospital.

Methods and Material:

The 156 cyto-histological results were collected and coded according to the Bethesda 2014 and FIGO system. The evaluation with the CLSI EP12-A2 guide allowed estimating the performance and quality of the test.

Statistical Analysis Used:

We performed a descriptive analysis of the cytological and histological data and correlation with the weight Kappa test. From the calculation of the likelihood ratios, the post-test probability was estimated using Bayes’ theorem.

Results:

In cytology, 57 (36.5%) were undetermined abnormalities, 34 (21.8%) low-grade squamous intraepithelial lesion (SIL), and 42 (26.9%) high-grade SIL. Of the total biopsies, 56 (36.9%) were cervical intraepithelial neoplasia (CIN) grade 1, 23 (14.7%) were both CIN grade 2 and 3. We determined sensitivity, specificity, a positive and negative predictive value of 94%, 74.6%, 58%, and 97.1%, respectively. We determined a moderate cyto-histological agreement (κ = 0.57). Atypical squamous cells of undetermined significance (40%), and cannot exclude high-grade squamous intraepithelial lesions (42.1%) that showed higher overdiagnosis results.

Conclusions:

The quality and performance of the Papanicolaou test show high sensitivity and moderate specificity. The concordance found was moderate and the proportion of underdiagnosis was higher in abnormalities of undetermined significance.
Acute necrotizing encephalopathy of childhood as a complication of dengue infection
Authors: Dar Mohammad Irfan , Bhat Vidushi , Bhardwaj Surbhi
Published: May 2023

Acute necrotizing encephalopathy of childhood (ANEC) is a clinico-radiological diagnosis characterized by acute onset, and progressive febrile encephalopathy preceded by viral-associated febrile illness and carries a very poor prognosis. We present a case of 9-year-old child with dengue virus-induced necrotizing encephalopathy who was managed with pulse methylprednisolone therapy followed by oral prednisolone. The rarity of ANEC in association with dengue and good neurological recovery with supportive treatment made us to report this case.
Final Report on Real-World Effectiveness of Sequential Afatinib and Osimertinib in EGFR-Positive Advanced Non–Small Cell Lung Cancer: Updated Analysis of the RESET Study
Authors: Kim Taeyun , Jang Tae Won , Choi Chang Min , Kim Mi-Hyun , Lee Sung Yong , Chang Yoon Soo , Lee Kye Young , Kim Seung Joon , Yang Sei Hoon , Ryu Jeong Seon , Lee Jeong Eun , Lee Shin Yup , Park Chan Kwon , Lee Sang Hoon , Jang Seung Hun , Yoon Seong Hoon , Oh Hyung-Joo
Published: May 2023

Purpose This study aimed to report the final analysis of time-on-treatment (TOT) and overall survival (OS) in patients with advanced-stage epidermal growth factor receptor (EGFR)+ non–small cell lung cancer (NSCLC) who received sequential afatinib and osimertinib and to compare the outcomes with other second-line regimens (comparator group).Materials and Methods In this updated report, the existing medical records were reviewed and rechecked. TOT and OS were updated and analyzed according to clinical features using the Kaplan-Meier method and log-rank test. TOT and OS were compared with those of the comparator group, in which most patients received pemetrexed-based treatments. A multivariable Cox proportional hazard model was used to evaluate features that could affect survival outcomes.Results The median observation time was 31.0 months. The follow-up period was extended to 20 months. A total of 401 patients who received first-line afatinib were analyzed (166 with T790M+ and second-line osimertinib, and 235 with unproven T790M and other second-line agents). Median TOTs on afatinib and osimertinib were 15.0 months (95% confidence interval [CI], 14.0 to 16.1) and 11.9 months (95% CI, 8.9 to 14.6), respectively. The median OS in the osimertinib group was 54.3 months (95% CI, 46.7 to 61.9), much longer than that in the comparator group. In patients who received osimertinib, the OS was longest with Del19+ (median, 59.1; 95% CI, 48.7 to 69.5).Conclusion This is one of the largest real-world studies reporting the encouraging activity of sequential afatinib and osimertinib in Asian patients with EGFR+ NSCLC who acquired the T790M mutation, particularly Del19+.
The Evolution of Automotive Technology: A Handbook ,2nd Ed.
Authors:   Technische Universiteit Eindhoven, Mom Gijs
Published: May 2023

The idea of "understanding the present through its history" is based on two insights. First, it helps to know where a technology comes from: what were its predecessors, how did they evolve as a result of the continuous efforts to solve theoretical and practical problems, who were crucial in their emergence, and which cultural differences made them develop into divergent families of artifacts? Second, and closely related to the first insight, how does a certain technology or system fit into its societal context, its culture of mobility, its engineering culture, its culture of car driving, its alternatives, its opponents? Only thus, by studying its prehistory and its socio-cultural context, can we acquire a true ‘grasp’ of a technology. The Evolution of Automotive Technology: A Handbook, Second Edition covers one and a quarter century of the automobile, conceived as a cultural history of its technology, aimed at engineering students and all those who wish to have a concise introduction into the basics of automotive technology and its long-term development.
Physicochemical Characteristics and Heavy Metals Assessment in Water and Sediments of Obodo Oilfield in Warri South Local Government Area of Delta State, Nigeria
Authors: Ibekwe U. M.
Published: May 2023

This study investigated the physicochemical characteristics and heavy metals levels in water and sediments of Obodo Oilfield in Warri South Local Government Area of Delta State using standard laboratory-approved APHA and ASTM methods. Results indicated traces of heavy metals present in the water and sediments. Temperature and TDS in the water samples were within the DPR established limits while TSS, Chemical Oxygen Demand, Salinity and Biochemical Oxygen Demand were higher than the control and well above the DPR established limits. The heavy metals present in the soil were all still within the permissible DPR limits, except for Cadmium which was higher than the control and DPR established limit. The results showed that the water and soil within the environment may have been considerably polluted and degraded by the operations of oil and gas production in the region. The study recommends that the activities of the oil and gas production companies be checked to ensure they are operating within the environmental standard regulations of the country and that the Government and necessary bodies should be proactive in checkmating illegal bunkering activities as they have become the major source of oil spills in the region.
Antioxidant and Antimalarial Activities of Methanol Extract of Picralima nitida Root Bark
Authors: Erharuyi O. , Eze A. O. , Imieje V. O. , Aghahowa S. E. , Falodun A.
Published: May 2023

Ethnomedically, the root, stem bark, seed or leaves of Picralima nitida are relevant in local preparations as antimalaria, antipyretic, antihypertensive and gastrointestinal agents. This study was therefore designed to determine the antimalarial and antioxidant effects of the methanol extract of the root bark of Picralima nitida using standard procedures. The antioxidant activity of the methanol root bark extract was evaluated using 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging method and ferric reducing antioxidant power (FRAP) assay. The antimalarial activity of the methanol root bark extract was investigated using the 4-day suppressive test in mice infected with Plasmodium berghei. The extract showed a concentration-dependent antioxidant activity with 50% inhibitory concentration (IC50) for free radical scavenging activity of 10.19 µg/mL, while the FRAP value was 0.17 ± 0.00 mM FSE/g Extract. The extract demonstrated significant antimalarial activity with 68.33% and 67.27% parasitaemia suppression at doses of 400 mg/kg and 800 mg/kg, respectively. The present study has shown that the root bark extract of P. nitida has antioxidant and antimalarial activities. This study does not only validate the claimed ethnomedicinal use of the plant as antimalaria but also has shown the plant as a potential source of active antimalarial agent.
Antifungal Potential of Black Mangrove Leave Extracts on Isolates of Smoked Bonga Fish Sampled from Oju-Ore and Iyana Markets in Ota, Ogun State, Nigeria
Authors: Daramola J. A. , Kester C. T. , Adonkie D. A.
Published: May 2023

The contamination of dried fishes by fungi poses serious threat to food safety and public health. This study was carried out on fungal contaminants found in smoked Bonga fish and to determine if there are any antifungal properties in the ethanol extract of Black Mangrove leaves. To achieve this, the study made use of six bonga fish samples purchased from two different markets, with six samples from three different retailers in each market, making a total of thirty-six samples. The antifungal properties of Black Mangrove (Avicennia germinans) were determined; the leaves were dried in the open air, followed by blending and extraction using absolute ethanol. Mycological examination of samples revealed the prevalence of seven types of fungi namely, Aspergillus flavus, Aspergillus niger, Aspergillus fumigatus, Rhizopus sp, Alternaria, Candida sp, Mucor sp. Concentration of 1% and 0.1% was applied, using the agar well diffusion method. The 1% ethanol extract showed very small zone of inhibition on the fungal isolates. Rhizopus, A. niger, A flavus, A. Fumigatus, Alternaria sp, Candida sp, Mucor sp showed zones of inhibition 2mm, 1mm, 0mm, 1mm, 0mm, 1mm, 2mm, respectively. The 0.1% ethanol extract showed no zone of inhibition. This showed that the extract had little or no antifungal effects on the isolates.
The Outpouring and Filling of The Holy Spirit: The Litera-Narrative Perspective of Pentecost
in Acts 2:1-13.
Authors: Putrawan Bobby Kurnia
Published: May 2023

The outpouring and infilling of the Holy Spirit was followed by carrying out God's missionary duties in Acts 2. This event was also adopted and became a tradition by some Christians in their religious life. The problem is that adoption only emphasizes how outpouring and fulfillment occurs. The purpose of this article is to discover the meaning of the outpouring and infilling of the Holy Spirit in the Love of Apostles in Acts 2: 1-13 and its implications for the church today. The Holy Spirit came upon the apostles and the others on the Day of Pentecost. Those who heard them speaking in tongues were perplexed and asked, “What does this mean?” (Acts 2:12). The question perseveres today. Pentecost teaches us that we should strive to have the same blessed experience as the disciples. God’s sanctions His church with the power of His Spirit so that He will be glorified among the nations. We need to remember that our purpose as the Lord’s church is not to focus on ourselves and our own happiness. Our purpose as Christians is to spread the knowledge of God to all the nations of the earth. If we lose our external focus, with the overall purpose of God’s glory, we may lose our reason for being. The result of this article is that the outpouring and fullness of the Holy Spirit is an important part in successfully carrying out God's mission. The method used in this brief study was a narrative theological analysis.
Tijelo i metafora mreže
Authors: Bubaš Josipa
Published: May 2023

Članak problematizira odnos društvenih metafora i znanstvenih i tehnoloških paradigmi te njihov odnos s obzirom na konceptualizaciju tijela, ali i društvenih odnosa.
Strategijske dileme kulturne politike sustava audiovizualne djelatnosti u Republici Hrvatskoj
Authors: Ahmetašević Edib
Published: May 2023

Kulturna politika Republike Hrvatske na području audiovizualne djelatnosti, prolazeći kroz tranziciju na različite načine ostavila je neizbrisive posljedice na ukupno područje audiovizualne djelatnosti. Uslijed raspada socijalizma, što predstavlja sistemsku tranziciju bivših država socijalističkog sistema prema (različitim modelima) kapitalističkog sistema, desila se i strukturna tranzicija kao rezultat globalnih promjena, pa je došlo do promjena kulturne politike u odnosu na audiovizualnu djelatnost Republike Hrvatske. Dezorijentirana kulturna politika usporila je razvoj audiovizualne djelatnosti prema kreativnoj industriji ili ga potpuno zaustavila. Dezorijentiranost kulturne politike nastala je uslijed neodgovornog društvenog ponašanja, nepoštivanja kulturne raznolikosti, nerazvijenog odnosa javnog, privatnog i civilnog sektora, odnosno strategijskih dilema kulturne politike. Kako bi se razvijala kreativna industrija potrebno je audiovizualnu djelatnost provoditi učinkovito i djelotvorno, a za što je neophodno redefinirati, razvijati i provoditi set strategija i instrumenata kulturne politike Republike Hrvatske na području audiovizualne djelatnosti.Interdisciplinarnim pristupom povezujući integrativnu teoriju društvenog ugovora i dilema suvremenih kulturnih politika na području audiovizualne djelatnosti ukazujem na važnost društveno odgovornog ponašanja, posebice privatnog sektora, koji ima veliku ulogu u razvoju filmske industrije kao profitno orijentirane kulturne industrije.Prijedlog: Razvoj kreativne industrije na području audiovizualne djelatnosti u Republici Hrvatskoj nije moguć bez uravnoteženja djelovanja strateških dilema kulturne politike, te na taj način uspostave ravnoteže između estetskih i tržišnih vrijednosti audiovizualne djelatnosti.
ética del rendimiento en el deporte contemporáneo:
Authors: Moldes Farelo Rocio , Briones Bermejo Almudena
Published: May 2023

Enmarcado en algunos de los principales postulados de la Teoría Crítica del Deporte, el presente trabajo tiene dos objetivos. El primero, mostrar cronológicamente el proceso expansivo de la ética del rendimiento extremo, catapultada por el carácter mediático del deporte de competición. El segundo, explorar la relación entre las expectativas económicas generadas por los grandes acontecimientos deportivos y el aumento de enfermedades psicológicas entre los deportistas de alto nivel.

El artículo está organizado en tres apartados. Los dos primeros describen el papel del deporte como transmisor privilegiado de valores guiados por la lógica del rendimiento y la individualización, en todas las esferas de influencia social. La última sección ofrece un breve análisis económico del deporte en España para ilustrar el impacto del deporte espectáculo y la influencia de la publicidad en la salud física y emocional de los deportistas.
Chair of Applied and Environmental Chemistry
Authors:   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Bojić Aleksandar , Miljković Milena ,   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Anđelković Tatjana ,   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Zarubica Aleksandra ,   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Ranđelović Marjan ,   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Mitrović Jelena ,   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry
Published: May 2023

Chair of the Applied and Environmental Chemistry was established in 1995 on the initiative of Prof. Dr. Milovan Purenović, who has been in the position of Head of the Chair since its establishment until his retirement in 2011. Prof. Dr. Aleksandar Bojić is currently Head of the Chair. Since its establishment until now, professors and associates of the Chair of Applied and Environmental Chemistry have been dedicated to the applied research, within the framework of innovative and development projects, which were realized through cooperation with industry. Also, a significant contribution has been made in the field of environmental protection, especially in the treatment of drinking and wastewater. Several operational technologies have been developed, some of them are protected by patents of the Intellectual Property Office of the Republic of Serbia. The Chair of Applied and Environmental Chemistry consists of four full professors, one associate professor, and one assistant professor.
Lithium-ion batteries
Authors:   University of Niš, Faculty of Sciences and Mathematics, Department of Chemistry, Nikolić Miloš
Published: May 2023

The demand for lithium-ion batteries is growing due to their characteristics (composition, size, charging time, capacity). There are various types that can be found on the market, which mostly depend on their purposes, which depend on their composition. They have different uses, starting with portable devices like mobile phones, cameras, and even smaller electric cars. They are being developed and improved (capacity, voltage, charging); additionally, their size is being reduced, which is particularly important in car industry where more rechargeable lithium-ion batteries are connected to get desired capacity. Similarly, to other types of batteries, these consist of cathodes, anodes and electrolytes, where gel or solid electrolyte is preferable to avoid the release of gas (hydrogen), and therefore their explosion or damage. From 2000 to 2010, the annual production of lithium-ion batteries in the world increased about 800%.
Цивилизационная матрица российского предпринимательства
Authors: Яфасов Абдурашид Яруллаевич
Published: May 2023

Актуальность статьи вызвана необходимостью перестройки структуры экономики вследствие расширяющейся прокси-войны США с Россией, в которую все сильнее вовлекаются европейские страны. Эта война переросла в жесткую цивилизационную войну и поставила ряд задач по перестройке экономики и реорганизации производства. Цель работы – новый подход к проблеме развития российского предпринимательства, основанный на цивилизационной матрице народов России, в которой неэкономические грани предпринимательства – нрав-ственность, культура, духовность – играют важную роль. Объектом исследований является организация инновационной деятельности, предметом исследований – формирование и развитие инклюзивной инновационной деятельности в России в условиях бифуркации. Исследован каскад бифуркаций в экономике страны, воз-никший с момента распада СССР. Проведен анализ санкционной политики западных стран, направленной на всестороннее ослабление экономики и разобщение российского общества, губительности этой политики для мирового сообщества и устойчивого развития. США и ЕС, сумевшие превратить свои денежные единицы в мировые валюты, имеют возможность бесконтрольного со стороны мирового сообщества печатания и выброса на мировой рынок своих валют вне зависимости от объемов производимых ими товаров и услуг, наращивания военных расходов. Показана необходимость принятия неотложных мер ускоренного развития в России современных производств. Институциональное развитие, ускорение развития креативных и адаптивных инноваций с выделением новых экспоненциальных технологий и расширением государственно-частного партнерства может обеспечить быстрые изменения структуры экономики, появление новых производств и модернизацию существующих предприятий. Обоснована необходимость мобилизации интеллектуального капитала и развития инклюзивной инновационной дея-тельности в целях обеспечения устойчивого развития России в условиях возни-кающих новых вызовов.