bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimized protocol for translatome analysis of mouse brain endothelial cells v2
Authors: OH Won-Jong
Published: August 2022

Brain endothelial cells (BECs) are important conduits that deliver oxygen and nutrients, protect parenchyma cells from toxins, and drain wastes to maintain brain homeostasis. Impairment of BECs has been implicated in diverse neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. Therefore, molecular analysis of BECs is important for understanding the molecular pathogenesis of these neurological diseases. Even though many transcriptome analyses for BECs have been developed, mRNA levels do not necessarily correlate with the levels of actively translated proteins. Translatome analysis using RiboTag mice, in which Rpl22, a ribosomal component, is tagged by the hemagglutinin epitope under Cre recombinase activation, could serve as an excellent tool that overcomes these caveats.However, implementation of this technique is limited by high noise-to-signal ratios as well as the low yield of mRNAs from BECs, which limits bulk gene expression analysis. In this study, we established a protocol to isolate highly pure mRNAs from BECs in the cortex of eight- to twelve-week-old male Tie2-Cre; Rpl22HA/HA mice by using a cell strainer to trap blood vessels prior to immunoprecipitation. According to the results of RT–PCR, the specificity of the mRNA pools isolated by our protocol was much higher than that of the pools isolated by the standard protocol. We were also able to generate a high-quality cDNA library for RNA-seq with the small amount of mRNA isolated with our protocol. Thus, this optimized method will be useful for future studies of BECs at the molecular level.
Overview of Adhesive Bonding Technology for Nano- and Microsystem Technics
Authors:   National Research University of Electronic Technology Zelenograd, Moscow, 124498, Russian Federation, Bespalov V.A. , Gusev E.E. ,   National Research University of Electronic Technology Zelenograd, Moscow, 124498, Russian Federation, Djuzhev N.A. ,   National Research University of Electronic Technology Zelenograd, Moscow, 124498, Russian Federation, Makhiboroda M.A. ,   National Research University of Electronic Technology Zelenograd, Moscow, 124498, Russian Federation, Fomichev M.Y. ,   National Research University of Electronic Technology Zelenograd, Moscow, 124498, Russian Federation
Published: August 2022

The review focuses on adhesive bonding technology, which is used both for manufacturing various micro- and nanoelectronic devices, sensors and microsystems, and for assembling or integrating various components. Information on the theory of adhesive bonding mechanisms is presented. The properties and applications of four classes of polymers are reviewed: thermoplastic, ther-mosetting, elastomeric, and hybrid. The classification of different mechanisms used to initialize the curing process of adhesives is presented. Existing methods of applying polymers to the wafer surface are described. The main types of designs and principles of operation of adhesive wafer bonding equipment are presented, as well as its main suppliers. Examples of procedures and suitable process parameters are given for both wafer bonding with a continuous layer of adhesive and wafer bonding with patterned adhesive layers (also called selective or local bonding). The conditions required to improve the quality of the adhesive bond and to reduce the density of defects are specified, including cases of bonding wafers made from different materials. Adhesive wafer bonding is used for the fabrication of three-dimensional integrated circuits, and for the integration of integrated circuits with microsystems such as infrared focal plane arrays, spatial light modulators (micromirror arrays), microtip arrays for data storage systems, and laser systems. Adhesive wafer bonding is also used for the fabrication of microcavities in packaging applications, for manufacturing of liquid crystal on silicon (LcoS) components, for thin-film solar cells, for radiofrequency components, for microfuel cells, for hard disk drive microactuators, for the bioMEMS and micrototal analysis systems.
Pengembangan E-LKPD Berbasis Problem Based Learning Menggunakan Live Worksheets pada Materi Perbandingan Di Kelas V Sekolah Dasar
Authors: Wijaya Fevy Marta , Nuraini Ni Luh Sakinah , Mas’ula Siti
Published: August 2022

Abstract: The Covid-19 pandemic that occurred around the world caused the inhibition of several areas of life, including education. Limited face-to-face activities become one of the problems that resulted in the process of delivering the material can not be done optimally. It takes a technology-based teaching materials that can help solve these problems, namely E-LKPD. The purpose of this research and development is to develop and determine the results of validation and practicality analysis of e-LKPD based Problem Based Learning using live worksheets in proportion material. The approach used in this study is R&D or Research and Development and the method used is ADDIE. The subjects of this study were 5th grade students of SDN Karangtengah 1 Blitar City. The trial was conducted on a small group of 6 students and a large group of 31 students. Product validation results from media experts obtained an average of 92 percent which is included in the valid category. Product validation results from material experts and teachers as users, respectively obtained 90 percent and 94 percent which are included in the valid category. The practicality of e-LKPD products from students showed a positive response with an average percentage of 95.27 percent in the very good category. So it can be concluded that E-LKPD product based on Problem Based Learning used in this proportion material is declared worthy use in learning.

Abstrak: Pandemi Covid-19 yang dialami banyak negara sebabkan terhambatnya beberapa bidang kehidupan tak terkecuali bidang pendidikan. Terbatasnya kegiatan tatap muka jadi salah satu masalah yang mengakibatkan proses sampaikan materi tidak dapat dilakukan dengan maksimal. Dibutuhkan sebuah bahan ajar berbasis teknologi yang dapat membantu menyelesaikan masalah tersebut, yaitu E-LKPD. Tujuan dari studi ini yaitu guna mengembangkan E-LKPD yang valid dan praktis yang berbasis “Problem Based Learning” memakai live worksheets pada materi perbandingan. Pendekatan studi ini memakai “Research and development” dengan metode ADDIE. Subjek dari studi ini ialah siswa kelas V SDN Karangtengah 1 Kota Blitar. Uji coba dilaksanakan pada kelompok kecil sebanyak 6 siswa dan kelompok besar dengan jumlah 31 siswa. Hasil dari validasi produk E-LKPD dari ahli media memperoleh rata-rata keseluruhan yakni 92 persen dalam kategori sangat valid. Validasi dari ahli materi diperoleh rata-rata keseluruhan yakni 90 persen dalam kategori sangat baik serta validasi dari Guru jadi pemakai memperoleh rata-rata keseluruhan yakni 94,2 persen dalam kategori sangat baik. Kepraktisan produk E-LKPD dari siswa menunjukkan respon positif dengan persentase rata-rata yakni 95,27 persen dalam kategori sangat baik. Dapat disimpulkan bahwa produk E-LKPD berbasis PBL yang digunakan pada materi perbandingan ini dinyatakan layak digunakan dalam pembelajaran.
Response of Different Safflower Genotypes to Anther Culture
Authors: NAKAS Dudu Büşra , AVCI Süleyman , KAYA Mehmet Demir
Published: August 2022

In this study; the responses of 12 safflower genotypes to anther culture were determined in MS medium containing increasing doses of BAP (0, 0.5, 1, and 2 mg L-1) and NAA (0, 0.1, and 0.5 mg L-1). Donor plants were grown under field conditions and the main capitulas were collected in early or late uninucleate stage. A pre-treatment was applied to their capitules at +4 °C for 3-4 days. Only cvs. Balcı and Linas produced regenerable callus among these genotypes. Although regenerable callus rate was higher in Balcı than Linas, shoot regeneration was achieved only in Linas with 0.5 or 1 mg L-1 of BAP + 0.1 mg L-1 of NAA combinations. In total, 8 shoots of Linas were moved to ½ MS medium consisting of 0.1 mg L-1 of NAA, but rooting of them could not be performed. In sum, among the 12 safflower genotypes, cvs. Balcı and Linas have higher anther culture regeneration potential; however, it is necessary to focus on shoot development and rooting on these cultivars in further experiments.
Pilot Project Exploring Low-tech Collaborative Board Gaming on Student Attitudes Toward Interprofessional Education
Authors: Stark Rachel Keiko , Opuda Eugenia
Published: August 2022

Objectives: The intent of this project was to explore the impact of a small, collaborative gaming experience among undergraduate students on student attitudes and beliefs about Interprofessional Education (IPE).
Methods: Health sciences librarians at two state universities used a low-tech, collaborative board game to facilitate small, in-person group gaming. The authors used an adapted version of the Interprofessional Attitudes Scale (IPAS), a validated instrument that measures the four domains of the 2011 IPEC Core Competencies for Interprofessional Collaborative Practice, as a pre/post assessment of the impact of the gaming experience.
Results: While anecdotal evidence indicated that playing a collaborative board game had an impact on the participating students, there was no statistically based evidence that collaborative board games increases positive or negative attitudes about IPE and interprofessional collaborative practice.
Conclusions: More student participation is required for statistical significance, recruiting students and ensuring that students have enough time to complete the game play is key to future possible success.
Delphi Method
Authors: Sablatzky Tenley
Published: August 2022

Description: The Delphi method is a process used to arrive at a group opinion or decision by surveying a panel of experts. The method was developed in the 1950’s and 1960’s by the RAND Corporation and since then has been used in many fields, including library and information science. During a Delphi study, selected experts respond to several rounds of questionnaires, and the responses are aggregated and shared with the group after each round. A Delphi study relies on the idea that collective group responses are superior to individual responses.
Purposes: Originally the Delphi method was created as a systematic, interactive forecasting method relying on a panel of experts. Since then, Delphi studies have been used for many purposes: creating policy, establishing guidelines, and identifying trends.
MLA 2022 Annual Meeting and JMLA Biannual Research Caucus Research Awards
Authors: Blake Lindsay E.
Published: August 2022

The MLA Research Caucus is pleased to announce the winners for best research papers and posters presented at the MLA 2022 Hybrid Meeting. Thank you to all the judges who volunteered their expertise to help select these deserving awardees both in the pre-judging phase and during the conference.
Preparation of polyamide 6 and its titanium dioxide photocatalytic composite powders for laser powder bed fusion
Authors: Chen Peng , Li Zhaoqing , Liu Sheng , Su Jin , Wang Haoze , Yang Lei , Yan Chunze , Shi Yusheng
Published: August 2022

Laser powder bed fusion (LPBF) additive manufacturing is an effective method to prepare three-dimensional ordered network titanium dioxide (TiO2) photocatalytic materials, therefore enhancing the absorption intensity of incident light and improving the photocatalytic efficiency. However, TiO2 is difficult to be directly sintered by LPBF due to the high melting point and brittleness. In this study, we prepared a polyamide 6 (PA6)-coated TiO2 photocatalytic composite powder for LPBF based on the dissolution precipitation polymer coating (DPPC) method and evaluated its LPBF processability. In the precipitation process of PA6, there was a significant crystallization exotherm with temperature recovery. Effective temperature control of this precipitation process had a significant effect on the morphology and particle size distribution of the precipitated powder. The increase of the dissolved concentration of PA6 to 150 g/L produced an obvious temperature gradient of the reactor, resulting in a wide particle size distribution and a powder with a characteristic porous surface. The prepared PA6/TiO2 composite powder presents a near-spherical porous-surfaced morphology, a high specific surface area of 240.5 m2/kg, an appropriate Dv(50) of 48.8 μm, and a wide sintering window of 26.6°C, indicating a good LPBF processability and potential of the photocatalytic application.
Role of catalyst in organic synthesis
Authors: Amrutkar Rakesh D , Bhalerao Shivam S , Bhoir Akanksha S , Bhusare Rina  H. , Bodhare Samiksha S , Borse Jagruti N.
Published: August 2022

Catalyst is a common word that comes across while studying chemistry especially while learning about chemical reactions. While some of the chemical reactions occur quickly, some take a long time and require extra materials or effort. In Chemistry, catalysts are defined as those substances which alter the rate of reaction by changing the path of reaction. Most of the time a catalyst is used to speed up or increase the rate of the reaction. However, if we go to a deeper level, catalysts are used to break or rebuild the chemical bonds between the atoms which are present in the molecules of different elements or compounds. In essence, catalysts encourage molecules to react and make the whole reaction process easier and efficient. The present review focuses on history, types and role of catalysis in organic reaction.
A brief review of high throughput screening in drug discovery process
Authors: Raval Keval Y. , Kansagra Jignesh J. , Ganatra Tejas H.
Published: August 2022

The pharmaceutical industry is fast pace growing field in which companies are focusing on research and development to identify new therapies and novel compounds which can provide better alternatives and which acts on new targets. For that matter, they are in need of rapid compound testing and screening. High throughput screening (HTS) is a important tool in drug discovery process which enables to screen more than millions of compound in a short period of time. It comprises of various tools which includes microtiter well plates, robotic arms and detectors. The basic application of HTS is to find ‘hits’, a compound from compound library which shows the affinity with the target molecule.
Formulation and evaluation of posaconazole loaded nanostructured lipid carriers for topical drug delivery system
Authors: Ghurghure Shrishail M , Jadhav Tanuja , Kale Sapana , Phatak Atual A
Published: August 2022

The aim of the present study was to formulate and evaluate Posaconazole loaded NLCs gel using solid lipid as GMS, liquid lipid as oleic acid and surfactants as tween 80 and span 80, with the help of high-speed homogenization followed by sonication technique to improve the bioavailability, to avoid the oral side effects, to achieve the site-specific delivery and to improve the patient compliance. NLCs of Posaconazole was prepared with different drug: carrier ratios using high speed homogenization followed by sonication technique. % entrapment efficiency for F3 batch of NLC was found to be more than 95%. SEM studies were carried out and depending on it F3 batch was found to have particle size range 200nm which was selected as optimized NLCs batch. IR, XRD and DSC were performed to identify the physicochemical interaction between drug and optimized formulation. The optimized NLCs was then incorporated into gel base to form Posaconazole loaded NLCs gel. The prepared NLCs gel were evaluated for viscosity, pH, spread-ability, extrudability and in-vitro drug release studies. It was found to be 34666 cps, 5.7, 12.22 ±0.8 cm, 85.34% and drug release of NLCs gel within 6hrs was 98.62% respectively. The obtained data for in-vitro drug release was putted in various mathematical kinetic models. Hence, F3 batch was selected as optimized batch.
Políticas públicas del deporte local y seccional en el departamento del Meta (Colombia). Revisiones preliminares desde el deporte social
Authors: González Ulloa Elkin , Chaparro Hurtado Héctor Rolando , Guzmán Ariza Claudia Marítza
Published: August 2022

El presente artículo resultado de investigación configura un primer elemento de análisis de las políticas públicas que en materia de deporte se han diseñado en el ámbito regional del departamento del Meta. El estudio, cuyo titulo lleva por nombre “Política pública y producción académica en torno al deporte social en la región”, tuvo desarrollo durante los años 2020 y 2021, y contó con el apoyo de la Universidad de los Llanos. Su objetivo principal se centró en identificar las concepciones y los lineamientos en torno a la construcción de política pública y de producción académica sobre el deporte social en la región. Su abordaje metodológico contempló el uso mixto de estrategias cualitativas y cuantitativas en tanto que contribuyó a corregir los inevitables sesgos presentes en uno u otro método. Algunos de sus resultados parten del diseño apriorístico de categorías en tanto unidades de análisis que sugieren pistas de análisis al rededor de los discursos y las prácticas sobre el deporte social a partir de políticas públicas, los modos de construcción y producción sobre políticas públicas entorno al deporte social y, finalmente, los efectos sociales y culturales de las políticas públicas en torno al deporte social.
Eficacia profiláctica de ondansetrón y dexametasona en náusea y vómito posterior a cesárea con opioides neuroaxiales como coadyuvantes. Ensayo clínico controlado
Authors: Parra-Güiza Rodolfo , Meléndez Hector Julio , Ochoa Miguel Enrrique
Published: August 2022

Introducción: la anestesia subaracnoidea es la técnica más empleada para realización de cesáreas usando opioides neuroaxiales, cuyos principales eventos adversos son náusea y vómito. Objetivo: establecer la eficacia de ondansetrón y dexametasona en la profilaxis de náuseas y vómitos en pacientes sometidos a cesárea. Materiales y métodos: una muestra de 300 embarazadas llevadas a cesárea no emergente bajo anestesia subaracnoidea fueron asignadas aleatoriamente en tres grupos: DEX (dexametasona 4 mg), OND (ondansetrón 4 mg), PLB (placebo 5 mL de solución salina normal). La técnica anestésica se estandarizó con 9 mg de bupivacaína al 0.5%, 100 mcg de morfina y 25 mcg de fentanilo Intratecal. Se evaluó el resultado de interés durante el intraoperatorio, a las 2, 6 y 24 horas post-anestesia, con un nivel de significancia α de 0,05. Resultados: el RR en el grupo DEX para vómito fue 0,46 (IC95%: 0,28-0,76), y para náusea fue 0,79 (IC95%: 0,64-0,96). En el grupo OND el RR para vómito fue 0,41 (IC95%: 0,24-0,69) y para náusea 0,75 (IC95%: 0,67-0,84). La severidad de la náusea fue menor y significativa en el grupo OND durante todo el tiempo evaluado (p<0.001). Conclusiones: la dexametasona 4 mg y el ondansetrón 4 mg mostraron eficacia para disminuir el riesgo de náusea y vómito postoperatorio en pacientes sometidas a cesárea bajo anestesia subaracnoidea cuando se usan opioides neuroaxiales. Trial registration: (ISRCTN 57227250). MÉD.UIS. 2018;31(1):31-8.
Estimación de valor económico de la Reserva de la Biosfera Calakmul, Campeche, México
Authors: Hernández Domínguez Thelma Alicia , Campo Saray Francisco José Martín del
Published: August 2022

Los activos ambientales son fuente de progreso social, económico y cultural de cada país, sin embargo, se han deteriorado por sobreexplotación del hombre y existe preocupación generalizada a nivel gubernamental y organizacional en su preservación. Los activos ambientales proporcionan variedad de bienes y servicios a la sociedad, la necesidad de valorarlos como instrumento económico permite contar con elementos tangibles y monetarios para planes de conservación adecuados. El objetivo de este estudio fue la estimación del valor económico de la Reserva de la Biósfera de Calakmul, Campeche, México. Fue necesario, analizar factores e indicadores de activos ambientales de la reserva, estudiar variables que inciden en el valor económico, así como, identificar y aplicar un método para valuación de la reserva. Se presentó un análisis de instituciones y normativas relativas a administración, preservación y cuantificación de activos ambientales, donde se identificó, que no existen normas específicas para valuación de áreas naturales en conjunto. Referente al proceso metodológico de valuación de activos ambientales, no existe un método de valuación único, no obstante, se aplicó el concepto de Valor Económico Total, que involucró los usos directos e indirectos relacionados con activos ambientales, para lo cual, fue necesario identificar beneficios que dichos activos representaron y realizar su cuantificación económica. Si bien, el valor que se concluye con este proyecto de intervención no es absoluto, corresponde a un valor de referencia y cumple con elementos que coadyuvan a sensibilizar a la sociedad en valoración de los recursos naturales y se compromete la subsistencia de generaciones futuras.
Pimenta malagueta in natura e liofilizada
Authors: Lemos Lúcia Mara dos Reis , Silva Maria Claudevânia Rabelo da , Aquino Clarissa Maia de , Almeida Érica Jamily do Nascimento , Santos Sandra Maria Lopes dos , Monte Antonia Lucivânia de Sousa
Published: August 2022

A pimenta malagueta (Capsicum frutescens L.) é destacada por seu conteúdo de macronutrientes e compostos bioativos, como vitaminas e compostos fenólicos com potencial antioxidante, sendo utilizada como especiaria na culinária brasileira. Este trabalho tem por objetivo analisar a composição físico-química, centesimal, mineral e microbiológica, além de quantificar compostos bioativos e a capacidade antioxidante de pimenta malagueta na forma in natura e liofilizada. As pimentas in natura e liofilizadas foram avaliadas quanto as suas características físico-químicas (pH, atividade de água, acidez titulável e sólidos solúveis totais), centesimal (proteína, lipídeos, umidade, cinzas, glicídios redutores e não-redutores e valor calórico) mineral (macro e microminerais) e microbiológica (coliformes totais, termotolerantes, bolores e leveduras e pesquisa de Salmonella). Foi observado que as pimentas malaguetas in natura e liofilizadas apresentaram boa composição nutricional, rica em compostos bioativos com potencial antioxidante. A secagem por liofilização não interferiu nos componentes avaliados.
Responsabilidade dos Administradores Societários das PME,s pela Violação do Dever de Diligência no Contexto da COVID-19
Authors: Machai João Romão , Amaral Giverage Alves do
Published: August 2022

A COVID-19 é uma realidade negativamente impactante em todos os ordenamentos económicos e constitui um mal que origina por si outros males, ao mobilizar a restrição das liberdades de circulação, comunicação física, destruição do Sistema fiscal, económico e desenvolvimento, do tecido empresarial, originando inacessibilidade da empregabilidade e incapacidade dos serviços sociais. Ora, as Pequenas e Médias Empresas são os mais afectados por esta situação, na medida em que dependem em muitas das circunstâncias dos serviços sociais e estatais que são fornecidos, para além de possuírem uma capacidade deficitária de auto-financiamento e resiliência em momentos de crise. Neste contexto, são frequentes situações em que os gestores com desrespeito total das regras legalmente instituídas, assim como das regras de mercado recorrem a manobras desonestas para manterem o funcionamento pleno, a exoneração no pagamento dos impostos e taxas instituídas, especulação dos preços de bens e serviços, incumprimento de contratos, açambarcamentos de mercadorias e despedimentos em massa dos colaboradores com recurso ao pretexto COVID-19 como motivo fundamental para estas decisões, as vezes com o desconhecimento total dos sócios, do Estado e em prejuízo dos trabalhadores e terceiros. Neste contexto importa a reflexão sobre a Responsabilidade dos Administradores Societários das PME,s pela Violação do Dever de Diligência no Contexto da COVID-19, dada a consciência de que nem sempre o mercado, ou a crise sanitária é responsável pelas situações que se verificam, visto que em muitas circunstâncias pode se deparar com gestores incapazes e que não prezam com uma boa Administração e que lesam os investidores (Sócios), os colaboradores (Trabalhadores), os terceiros e o Estado.
ensino híbrido no contexto da pandemia
Authors: Bernardo Julio Cesar Oliveira , Karwoski Acir Mario
Published: August 2022

A pandemia de Covid-19 trouxe desafios para o contexto educacional. Esta pesquisa, a partir de busca em plataforma de periódicos, objetivou investigar abordagens do Ensino Híbrido no contexto pós-início da pandemia. A partir do problema de pesquisa sobre o quanto essa prática de ensino pode fomentar as práticas pedagógicas atuais, a análise preliminar dos artigos encontrados, por meio de um estado da arte, demonstrou que o tema tem sido objeto de estudos em todos os níveis de ensino e apresenta três tendências no contexto educacional. Os resultados preliminares apontam mudanças possíveis, inovadoras e com potenciais desdobramentos para mais pesquisas.
Blockchain technology for international trade: beyond the single window system
Authors: Han Jeong Hugh
Published: August 2022

This chapter considers how supply chains can be made more efficient in order to achieve the objective of maximising the stakeholders’ economic profitability, while meeting the diverse range of customer requirements. The underlying discussion pertains to the role of emergent blockchain technology which is beginning to influence how firms and IT service suppliers improve supply chain agility and flexibility using blockchain. It goes on to discuss the role of blockchain in global supply chain management and cross-border trade and explores the future of supply chains underpinned by blockchain.
Candida strains and resistance patterns identified in a tertiary hospital
Authors: DEMİR Canan
Published: August 2022

Objectives: Candida species are the most common fungal infectious agents. Candida species are important with their increasing frequency in hospital-acquired infectious agents. The issue of antibiotic resistance, which frequently encountered in bacterial agents, is unfortunately also valid in fungal infections. In the present study, we aimed to determine the resistance of Candida species in our hospital including 1350 patient beds, the materials and units of production, and their sensitivity to antifungal drugs, in particular fluconazole.
Methods: Yeast growths, colony morphology, germ tube formation and VITEK 2 Compact automated identification system detected in the samples evaluated in the central laboratory of our hospital between January 1, 2021 and December 31, 2021 were typed. Antifungal susceptibilities, especially fluconazole, caspofungin, and amphotericin B susceptibilities, were determined by an automated system.
Results: In total, 2446 within the Candida growing sample was determined as 49% Candida albicans, 26.9% Candida parapsilosis, %17.9 Candida tropicalis, Candida glabrata and Candida krusei were observed in 2.3%. Although the distribution of Candida species in other intensive care units and services was comparable to the general incidence, C. albicans was detected in 38%, C. parapsilosis 30% and C. tropicalis 27% in surgical intensive care units. Moreover, C. tropicalis was the dominant species in the neonatal intensive care unit (75%).
Conclusions: In the present study, C. albicans was the most common candida species, and C. parapsilosis was the second most frequently reproduced species. It has been suggested that resistance patterns differ between species and between wards, therefore species identification and susceptibility analysis are important, and these should be taken into account when starting empirical, preemptive and antifungal treatment.
Editors' Responsibility for Publishing High-Quality Research Results: A Worldwide Study Into Current Challenges in Quality Assessment Processes
Authors: Krapež Katarina
Published: August 2022

The contemporary scientific community faces significant challenges in assuring research credibility. Since the onset of the COVID-19 pandemic, there has been an even greater interest in swift publications of valid research results, and individual editors of reputable academic journals might feel pressured to ensure high quality of published papers. Aiming to explore how editors perceive their management of the quality assessment processes and to identify decisions and processes which editors believe to be the most critical for securing high-quality publications, we conducted a qualitative survey. 258 editors of scientific journals from 42 countries participated in the study.  Key findings of the first part of the study show that across disciplines, editors perceived the manuscripts as excellent if they were innovative, scientifically sound, well-written and well-argued, addressed a significant topic, contained useful results, and had the potential to change (improve) something. Secondly, originality emerged as the leading quality criteria in manuscript quality assessment, followed by validity and significance. Finally, results indicate that factors influencing the overall complexity of editorial quality assessment are: (i) clearly defined minimum threshold of required quality, (ii) consistency of assessment between individual quality criteria, and (iii) experience of the editor.
Private Returns to Education in Developing Countries: Evidence from Kosovo
Authors: Ukaj Mic , Hoti Avdullah , Topxhiu Rahmije
Published: August 2022

This paper aims to assess the reward that employees receive from education in the Kosovo labour market in terms of a wage premium. The incentive to address this issue comes as a result of the high increase in participation in formal education in recent decades, especially in higher education. The research is mainly focused on private benefits from education, in terms of wage increases, assessed through a private return to investment in education. For this research, microdata from the Labour Force Survey has been used, conducted by the Kosovo Agency of Statistics. We used only the sample of wage employees, which includes 9,300 individuals. The econometric model used in processing the empirical results is based on Mincer's wage equation. The results presented in section 5 reveal that the rate of return on education investment has been sufficient to keep the demand for education investment alive. In comparison to the other two levels of education (primary and secondary), the results indicate a very high rate of return to tertiary education, justifying the high enrollment in this level of education. Females receive a higher rate of return than males.
Digital Transformation Of Legal Education
Authors: Yuliya Kharitonova  , Larisa Sannikova
Published: August 2022

Employers and practicing lawyers face the challenges of digitalisation in society. Many lack enough experience and skills to work with digital technologies. To increase the competitiveness of their graduates, universities have established advanced training programmes related to digital technologies and law; however, a common approach has yet to be found. The development and implementation of the proposed Framework for the Digital Competence of Lawyers will assist in solving novel problems in the field of legal education. This framework should include general digital competencies for all legal professions. The use of computer or virtual simulators, demo versions of popular digital platforms, and LegalTech hackathons within the educational process has been proposed to improve the digital skills of law students, which will allow examining the essence of ongoing processes and better acquire theoretical knowledge about new technologies.
The Effects of Legislation on Surrogacy Tourism
Authors: Sendi Yakuppur
Published: August 2022

Statistics show that one in every six couples are currently infertile. Due to new artificial reproductive techniques, infertile couples have a whole new range of possibilities to become parents. Surrogacy tourism is a type of medical tourism in which couples with infertility travel to other countries to rent wombs of surrogate woman. At present, surrogacy tourism is a multi-billion-dollar industry. One of the main reasons for surrogacy tourism is that surrogacy is not legal in some countries. It appears that legislation, ethical understanding, and concerns that human rights will be violated prevent people from benefiting from such developments while medicine continues to develop and advance. Economics also drive surrogacy tourism. Religion is also a significant factor in choosing the destination for the treatment. Infertile couples are more likely to prefer countries where their religious beliefs are respected and considered during the treatment. This paper seeks to highlight the effects of the legal provisions and precedents about surrogate motherhood on surrogacy tourism.
Evaluation of the Performance of Basmati Rice (Oryza sativa) Transplanting at Different Dates with Nutrient Sources under the Method of SRI
Authors: Sharma Arpita , Puniya R. , Nguyen Anh T.
Published: August 2022

Background: With growing fertilizer prices and fertilizer-related environmental concerns, Basmati 370 holds a unique position in the rice world due to its price, fragrance, quality and low fertilizer demands as compared to hybrid varieties; thus, shifting this crop to an organic or integrated nutrient management system is a feasible option. Methods: A field experiment was carried out at Jammu (J and K) during the Kharif season of 2014 to evaluate the performance of Basmati 370 transplanted at three different dates with five integrated nutrient sources. Result: The results of this investigation indicated that the rice transplanted on June 30 produced significantly higher dry matter accumulation (857.61 g/m2) with a concomitant increase in the grain yield (3.3 t/ha) over July 15 (3.0 t/ha) and July 30 (2.8 t/ha). The application of 100% RDF in the form of inorganic fertilizer recorded significantly higher grain yield (3.3 t/ha) and straw yield (5.6 t/ha) being at par with VC+FYM+NOC and GM+VC. The highest net returns were recorded on June 30 transplanting (₹80,501) with a benefit-cost ratio of 2.8. In the case of nutrient sources, higher net returns were fetched with 100% RDF (84,892) with a benefit-cost ratio of 3.4.
Farmers’ Perceptions on Drought, Low Soil Fertility, Coping Strategies and Preferred Traits of Beans (Phaseolus vulgaris L.) in Balaka District of Malawi
Authors: Kachiguma N.A. , Ifie B.E. , Maliro M.F.A. , Tongoona P.B. , Ofori K.
Published: August 2022

Background: Bean is an important nutritious food and cash crop. Bean productivity is low mostly due to various abiotic, biotic and socio-economic constraints. The aims of this study were to assess constraints to high bean seed yield productivity, determine farmers’ perceptions on drought and low soil fertility, strategies farmers are practicing to adapt to the constraints and preferred bean traits. Methods: A Participatory rural appraisal approach was applied by administering a questionnaire to 139 household representatives from Bazale, Phalula and Utale areas in 2017. Result: Farmers (68.4%) cultivated beans under irrigation in winter (dry) season and most of them practiced sole cropping. Constraints to high bean seed yield productivity include drought and low soil fertility (31.7%) and deforestation (81.3%) contributed a lot. Farmers (44.6%) implemented afforestation, 32.4% grew early maturing bean varieties, while 20.9% practiced conservation agriculture. Farmers were not involved in variety development as indicated by 91.4% of the respondents. However, farmers preferred determinate plant type (95.7%), creamy taste (61.2%) and high number of pods per plant (47.4%). These farmers’ preferred traits need to be considered in the ongoing bean improvement program(s) to increase adoption rate of improved varieties.
​​Levels of Metals and Nutritional Composition of Garden Cress (Lepidium sativum) Seed, in Southern Ethiopia
Authors: Feleke Ashenafi , Bibiso Mesfin , Lelago Alemu
Published: August 2022

Background: Garden cress (Lepidium sativum) belongs to the Cruciferae family, a fast-growing edible herbaceous plant. This study aimed to determine the essential and non-essential metals levels and nutritional composition of garden cress seed grown in the Wolaita Zone in southern Ethiopia. The study was carried out by collecting garden cress cultivated in Jage, Wandara, Taba, Hilena, Siyara, Demba Gale, Himbecho, Afama and Gara sites of the Wolaita Zone, Southern Ethiopia. Methods: 27 triplicate garden cress seed samples were collected from nine selected sites and digested by the wet digestion method. The level of metals in the sample was determined by using FAAS. Result: The result showed that the average concentration of K, Ca, Mg, Fe, Cu and Zn in the garden cress seed samples in mg/100 g dry weight, were in the range of 1179.76 to 1226.79, 249.52 to 291.62, 314.84 to 341.44, 7.29 to 8.48, 3.72 to 5.44 and 5.80 to 6.68, respectively. The average concentration of non-essential lead metal was not detected in all sample sites. The proximate composition of the garden cress seed sample was in the range of 19.68% to 22.87% for protein, 8.30% to 10.27% for Crude fiber, 20.72% to 24.17% for fat, 3.44% to 4.63% for ash, 1.37% to 2.59% for moisture, 40.56% to 43.24% for carbohydrate and 332.96 to 344.19 Kcal/100 g for energy. The study confirmed that the garden cress seed was a good source of essential metals and an excellent source of protein, carbohydrate, fiber, energy and fat contents. The concentrations of metals in garden cress were permissible compared with recommended permissible limits of WHO/FAO as well as USDA.
Suitability of Agricultural Land of Jajmau Area, Kanpur Uttar Pradesh Ganga’s Riverine Cities
Authors: Dwivedi R. , Chelliah T.R. , Khare Deepak
Published: August 2022

Background: In this paper, study about the agricultural Land suitability at the Jajmau area in Kanpur Uttar Pradesh to find out the chemical pollution in soil due to industrial waste. The tanning industry in the Jajmau had been established since 1940, now the impact of such industries on the Landis a severe threat to human life.
Methods: The soil sample for three different seasons gets collected and stored, After wards with the help of leaching process and ICP- MS test, to find out the traces of heavy metals present in an agricultural field near the banks of Ganga River, namely Jajmau area.
Result: It is find that the traces of different elements of Soil samples for pre-monsoon are in parts per million (ppm) As 25-55 ppm, For monsoon season soil sample, the traces of elements like As 25-42 ppm Similarly, for the post-monsoon soil sample, the traces of elements are such as As 67-109 ppm. Toxic elements like Fe, Mg and as are the elements, Having exceeded value is very at most of the sample. It can hurt an ecosystem like human health, Environmental condition, aquatic life and life food cycle.
Implementing SBIRT to Address Maternal Marijuana Use
Authors: Latiolais Emily , Morse Courtney , Warnke Keleigh , Forest Sharron
Published: August 2022

A quality improvement project conducted at 3 Texas hospitals to implement a new systematic process to address maternal marijuana use among breastfeeding mothers. The new process was created using the evidence-based Screening, Brief Intervention, Referral to Treatment (SBIRT) model to address maternal marijuana use. Nurses screened all postpartum mothers for marijuana use at each of the 3 hospitals. Mothers who reported ever using marijuana were advised to abstain while breastfeeding and given educational materials and a treatment referral card. Among all 3 hospitals, the mean nurses’ adherence to the SBIRT process was 69 percent, exceeding the project aim of 50 percent adherence. SBIRT, which has been used extensively with other populations and settings, was easily translated into practice for use with postpartum mothers who reported using marijuana. A systematic process using SBIRT may help mitigate the risk of harm for infants of mothers who use marijuana.
The Effects of Entrepreneurs’ Optimism and Mindfulness on Psychological Well-Being
Authors:   IAGBT, Kim Jong-Wook , Lee Mi-Kyeong , Lee Jong-Keon
Published: August 2022

Purpose – The purpose of this study was to examine the impact of optimism on emotional exhaustion and psychological well-being of entrepreneurs, and the impact of mindfulness on emotional exhaustion and psychological well-being of entrepreneurs and analyzed the mediating effects of emotional exhaustion on relationships between these variables.
Design/Methodology/Approach – Data were collected through a questionnaire for 156 CEOs of start-up companies doing business in Seoul and Gyeonggi-do to examine the relationship between research variables.
Findings – The findings of this study are as follows. First, mindfulness has been shown to have positive effects on emotional exhaustion, autonomy, environmental mastery, and purpose in life. Second, optimism has been shown to have a partly positive effect on psychological well-being. Third, mindfulness has been shown to have positive effects on psychological well-being. Fourth, emotional exhaustion has been shown to have negative effects on autonomy, environmental mastery, and purpose in life. Fifth, emotional exhaustion has been shown to meditate the relationship between mindfulness and psychological well-being.
Research Implications – Results of this study suggested theoretical implications as follows. First, this study has theoretical significance in that empirical analysis found that optimism raises the level of environmental mastery and purpose in life. Second, the findings are theoretical in that empirical analysis revealed that the emotional exhaustion of entrepreneurs had a negative impact on autonomy, environmental mastery, and purpose in life. Finally, the findings are theoretical in that they suggest that emotional exhaustion is an important variable that mediates the relationship between mindfulness and psychological well-being.
Results of this study suggested practical implications as follows. First, the results of this study suggest practical implications that it is important to devise a plan to increase the level of mindfulness of entrepreneurs. Second, the results of this study suggest practical implications that it is important for entrepreneurs to make efforts to increase the level of optimism. Finally, the results of this study suggest practical implications that various interests should be paid to prevent entrepreneurs from burning out emotionally.
The effect of product quality and price toward repurchase intention at Taco Casa Bali during Covid-19 pandemic
Authors: Werdiastuti Putu Ema , Agustiono Agustiono
Published: August 2022

Due to Covid-19 pandemic, sales and the number of visitors to Taco Casa Bali have decreased. In this changing situation, repurchase inten­tion is very important for the continuity of the culinary business, so it is important to find out the factors that influence it. The research aimed to determine the effect of product quality and price in influ­encing customer satisfaction on customer repurchase intentions at Taco Casa Bali during Covid-19 pandemic. Although variables in this research are not new, there is still inconsistency in the findings and also this paper factors in Covid-19 pandemic situation. Sample size consisted of 97 respondents. Using Smart-PLS version 3.9, results showed that product quality does not affect the customer repurchase intention. Price and customer satisfaction affect the customer repur­chase intention. Product quality and price affect customer satisfac­tion. Customer satisfaction does not act as a mediator for product quality and price on customer repurchase intention. Implications of practice for this paper are discussed in the end of section.
Detection of learning styles with prior knowledge data using the SVM, K-NN and Naïve Bayes algorithms
Authors: Hasibuan Muhammad Said , Aziz RZ Abdul
Published: August 2022

The two types of automatic learning style detection approaches are data driven (DD) and literature based (LB). Both methods of automatic learning style detection have advantages over traditional learning style detection methods because they use external data sources, such as forums, quizzes and views of teaching materials, that are more accurate than the questionnaires used in traditional styles of detection. The results of automatic detection, on the other hand, do not always reflect learning styles. This paper presents a learning style recognition method that uses data from the learner’s internal source, namely prior knowledge, to overcome these challenges. Prior knowledge is proposed because it is based on the learner’s knowledge or skills, which better reflect the learner’s characteristics, rather than on the learner’s behaviour, which tends to be dynamic. By using past knowledge, this paper presents a method for detecting automatic learning patterns. The learning style detection framework is unique in that it consists of three stages: prior knowledge question development, prior knowledge measurement and learning style detection using the Support Vector Machine (SVM), Naïve Bayes and K-Nearest Neighbour (K-NN) classification methods. The accuracy of learning style detection using prior knowledge data was higher than detection results using behavioural data or hybrid data (prior knowledge + behaviour) in this study
A deep learning model to detect the brain tumor based on magnetic resonance images
Authors: Kohsasih Kelvin Leonardi , Agung Rizky Muhammad Dipo , Rosnelly Rika , Widjaja Willy Wira
Published: August 2022

Deep learning techniques have been widely used in everything from analyzing medical information to tools for making medical diagnoses. One of the most feared diseases in modern medicine is a brain tumor. MRI is a radiological method that can be used to identify brain tumors. However, manual segmentation and analysis of MRI images is time-consuming and can only be performed by a professional neuroradiologist. Therefore automatic recognition is required. This study propose a deep learning method based on a hybrid multi-layer perceptron model with Inception-v3 to predict brain tumors using MRI images. The research was conducted by building the Inception-v3 and multilayer perceptron model, and comparing it with the proposed model. The results showed that the hybrid multilayer perceptron model with inception-v3 achieved accuracy, recall, precision, and fi-score of 92%. While the inception-v3 and multilayer perceptron models only obtained 66% and 56% accuracy, respectively. This research shows that the proposed model successfully predicts brain tumors and improves performance