bluuebunny/crossref_metadata_2025 huggingface dataset:
LLIN Evaluation in Uganda Project (LLINEUP2) – Factors associated with coverage and use of long‑lasting insecticidal nets following the 2020-21 national mass distribution campaign: a cross-sectional survey of 12 districts
Authors: Okiring Jaffer , Gonahasa Samuel , Nassali Martha , Namuganga Jane F. , Bagala Irene , Maiteki‑Sebuguzi Catherine , Opigo Jimmy , Nabende Isaiah , Nangendo Joanita , Kabami Jane , Ssewanyana Isaac , Kiwuwa Steven M. , Nankabirwa Joaniter I. , Dorsey Grant , Briggs Jessica , Kamya Moses R. , Staedke Sarah G.
Published: April 2022

Background. In 2020-2021, long-lasting insecticidal nets (LLINs) were distributed nationwide in Uganda during the COVID-19 pandemic. A cross-sectional survey was conducted in 12 districts to evaluate the impact of the campaign 1-5 months after LLIN distribution. Methods. During April-May 2021, households were randomly selected from target areas (1-7 villages) surrounding 12 government-run health facilities established as Malaria Reference Centres; at least 50 households were enrolled per cluster. Outcomes included household ownership of LLINs distributed through the universal coverage campaign (UCC) (at least one UCC LLIN), adequate coverage of UCC LLINs (at least one UCC LLIN per 2 residents), and use of LLINs (resident slept under a LLIN the previous night). Multivariate logistic regression models were used to identify household- and individual-level factors associated with outcomes, controlling for clustering around health facilities.Results. In total, 634 households, with 3,342 residents and 1,631 bed-nets, were included. Most households (93.4%) owned at least 1 UCC LLIN, but only 56.8% were adequately covered by UCC LLINs. In an adjusted analysis, the factor most strongly associated with adequate coverage by UCC LLINs was fewer household residents (1-4 vs 7-14; adjusted odds ratio [aOR] 12.96, 95% CI 4.76-35.26, p<0.001; 5-6 vs 7-14 residents; aOR 2.99, 95% CI 1.21-7.42, p=0.018). Of the 3,166 residents of households that owned at least one UCC LLIN, only 1,684 (53.2%) lived in adequately covered households; 89.9% of these used an LLIN the previous night, compared to 1034 (69.8%) of 1,482 residents living in inadequately covered households. In an adjusted analysis, restricted to residents of inadequately covered households, LLIN use was higher in children under-five than those aged 5-15 years (aOR 3.04, 95% CI 2.08-4.46, p<0.001), and higher in household heads than distantly-related residents (aOR 3.94, 95% CI 2.38-6.51, p<0.001). Conclusions. Uganda’s 2021-21 campaign was successful, despite the COVID-19 pandemic. In future campaigns, strategies should be adopted to ensure high LLIN coverage, particularly for larger households. A better understanding of the drivers of LLIN use within households is needed to guide future interventions, educational messages, and behaviour change communication strategies; school-aged children and distantly-related residents appear vulnerable and could be targeted.
Sustainability consciousness, green innovation initiatives and CSR practices:A way forward for developing countries:
Authors: Chishti Mazhar , Bashir Rizwana , Safdar Sofia , Mancinelli Tanja
Published: April 2022

Green innovation hasn't gotten much attention as a factor of environmental policies in developing countries like Pakistan. Green innovation and long-term financial performance are very much dependent yet; despite the fact that many studies have looked into the influence of various corporate social responsibility (CSR) activities on environmental sustainability, few have looked into the implications of green innovation strategies and sustainability. From January to December 2021, data were collected from the respondent of 184 listed companies of 12 sectors of Pakistan Stock Exchange (PSX). The results were estimated by using partial least squares structural equation modeling (PLS-SEM). According to the findings of the study, all aspects of CSR were determined to be favorably significant in promoting environmentally sustainable growth except one aspect of CSR to consumers. Furthermore the mediation effect of green innovation is also aided by environmentally sustainable development.
Thermoacoustic sensor-based system for detection of respiratory diseases in chicken (Gallus domesticus L.)
Authors: Mugide Catherine , Ocen Gilbert Gilibrays , Omara Timothy , Lusiba Badru , Semwogerere Twaibu , Alunyu Andrew Egwar
Published: April 2022

Objective
Diseases such as avian influenza, infectious laryngotracheitis and Mycoplasma gallisepticum responsible for huge losses in poultry target the respiratory system of birds. The aim of this study was to design and assemble a system which can be used to detect respiratory diseases among chicken basing on the abnormal vocalization and temperature of chicken.
Results
The proposed system was assembled and operated in a way that the acoustic and thermal sensors acquire sound and temperature from the chicken environment, sends them to a microcontroller which then interprets the input and in case of abnormal sounds or temperature due to cough or snore, the system administrator and the farmer are notified. The results illustrated that the system could be used to improve the detection of respiratory disease outbreaks in chicken, which can potentially minimize losses in poultry farming.
Surgical approach could be a major factor in placenta Previa outcome: a retrospective study
Authors: Uwais Ala , Hijazin Marleen , Satari Anas , Al-abadleh Ahmed , Al-kharabsheh Ahlam , Abufraijeh Seham
Published: April 2022

Background:
Placenta previa carry high morbidity and mortality due to massive hemorrhage occur during surgery. So, there should be a standard surgical approach with less morbidity.
Methods:
This is a retrospective study that reviewed all deliveries in Al-karak governmental hospital between 2019–2022. Placenta previa cases were divided into two groups according to management. Group A was managed by incising the uterus at the level of fundus to avoid opening through the placenta, while Group B was managed by opening the lower uterine segment and delivering the baby through placenta after incising it.
Result:
This study included 26 cases of placenta previa, 12 of them (Group A) were managed by avoiding the placenta and the other 14 cases (Group B) were managed by opening through the placenta. There was no difference between the two groups in terms of age and the number of previous caesarean sections (table 1). Patients who underwent the suggested surgical approach (Group A) had less blood loss (Mdn = 775 cc) while Group B (Mdn = 1700 cc) U = 20.0 p = 0.001 was significantly higher in terms of blood loss. Similarly, the number of blood units given for Group B (Mdn = 5 units) was significantly higher than Group A (Mdn = 1 unit) U = 29.5. p = 0.005. lastly, the duration of hospital stay for Group A (Mdn = 2 days) was significantly less than Group B (Mdn = 6 days) U = 10.0. p = 0.000
Conclusion:
Incising the upper uterine segment to avoid the placenta may have better outcome regarding blood loss and its consequences.
Synthesis and Characterisation of Nano-silica Based on Pumice Using NaOH
Authors:   Department of Physics, Faculty of Mathematics and Natural Science, University of Lampung, Jl. S. Brojonegoro No. 1, Bandar Lampung, 35145 Indonesia, Manurung Posman , Ginting Erika Sempana ,   Department of Physics, Faculty of Mathematics and Natural Science, University of Lampung, Jl. S. Brojonegoro No. 1, Bandar Lampung, 35145 Indonesia, Ginting Ediman ,   Department of Physics, Faculty of Mathematics and Natural Science, University of Lampung, Jl. S. Brojonegoro No. 1, Bandar Lampung, 35145 Indonesia, - Suprihatin ,   Department of Physics, Faculty of Mathematics and Natural Science, University of Lampung, Jl. S. Brojonegoro No. 1, Bandar Lampung, 35145 Indonesia
Published: April 2022

Nano-silica was synthesised from pumice by extraction method using sodium hydroxide (NaOH), sulphuric acid (H2SO4) and hydrochloric acid (HCl). The raw material of pumice was collected from local area, Tanggamus-Lampung Indonesia. After grinding, the pumice powder was activated at 450°C for 2 h before mixing with NaOH for extraction. After extraction, the powder was heated at 800°C for 4 h, to maintain the silica is in amorphous phase. Physical characteristics were analysed using transmission electron microscopy (TEM) for measuring particle size, Brunauer-Emmett-Teller (BET) technique for surface area measurement, x-ray diffraction (XRD) for structure and x-ray fluorescence (XRF) for determination of oxides. XRD analysis proved that besides amorphous nano-silica, there are peaks of sodium sulfate (Na2SO4) as representation of crystalline structure. The maximum silicon dioxide (SiO2) content was found on 3.0 molar (M) NaOH. The highest surface area of 165 m2 /g was obtained in sample of 3.5 M NaOH. The truly amorphous nano-silica content was found in NaOH of 3.0 M. The formation temperature may occur between 1100°C–1200°C. The particle size is in the range of 9 nm–17 nm.
Investigating Bi2O3-B2O3-BaO Glass Systems for Radiation Shielding Applications
Authors:   Department of Nuclear Medicine, Ümraniye Training and Research Hospital, 34764 Ümraniye, İstanbul, Turkey, Gülmen Mergim , Bükte Yaşar ,   Department of Radiology, Ümraniye Training and Research Hospital, 34764 Ümraniye, İstanbul, Turkey
Published: April 2022

This research was conducted to study x-ray and gamma radiation shielding parameters such as mass attenuation coefficient, mean free path, half value layer, tenth value layer, effective atomic numbers, effective electron density for the xBi2O3-(95-x)B2O3-5BaO (where x = 20 mol%, 35 mol%, 50 mol%, and 70 mol%) glass systems with different molar composition. The studied ceramic specimens were denoted by BB20, BB35, BB50 and BB70 and their density values were 4.438 g/cm3 , 5.973 g/cm3 , 7.156 g/cm3 , and 8.005 g/cm3 , respectively. Radiation shielding parameters of the samples were investigated by using web based XCOM programme. The obtained results revealed that the highest mass attenuation coefficients were reported for BB70 sample, which has the highest Bi2O3 additive in its chemical structure. At 7 MeV photon energy, half value layer (HVL) values were reported as 5.7812 cm, 3.8065 cm, 2.8533 cm, and 2.2457 cm for BB20, BB35, BB50 and BB70, respectively. Therefore, It can be concluded that the present bismuth sesquioxide based glasses in the Bi2O3-B2O3-BaO glass system have a good quality in radiation protection purposes. Therefore, this glass system can be used as an alternative to conventional materials with the right molar compositon in its chemical formation.
Emulsion Liquid Membrane Screening for Ibuprofen Removal from Aqueous Solution
Authors:   School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, 14300 Nibong Tebal, Pulau Pinang, Malaysia, Mohd Harun Mohd Hazarel Zairy , Ahmad Abdul Latif ,   School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, 14300 Nibong Tebal, Pulau Pinang, Malaysia, Rajandram Logaisri ,   School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, 14300 Nibong Tebal, Pulau Pinang, Malaysia
Published: April 2022

Ibuprofen (IBP) has become increasingly widespread in our environment, posing a major problem for treatment by its high occurrence in low concentrations. Emulsion liquid membrane (ELM) technology has emerged as an alternative solution for removing low concentration pollutants from contaminated sources. This study screened ELM formulations for the removal of IBP from an aqueous solution. Emulsion screening was conducted using a series of reactants, including petroleumbased diluent, green diluent, and acidic/alkaline stripping agent. The ELM system, which included hexane (diluent), 0.1 M sodium carbonate, Na2CO3 (stripping agent), 2 wt% Aliquat 336 (carrier) and 4 wt% Span 80 (surfactant), achieved the highest IBP extraction efficiency of 97%.
Turkish preschool children's representations of friendship: Story completion method adaptation study
Authors: NUR İmray , AKTAŞ ARNAS Yaşare
Published: April 2022

In the preschool period, children's friendships considered a crucial developmental task. Hence, it is critical to evaluate children's mental representations of friendships during this period. This study aims to evaluate the validity and reliability of the story completion protocol designed to evaluate preschool children's mental representations of their friendships in school settings for Turkish children. The Preschool Friendship Story Completion Task consists of six stories, one of which is warming. The stories were translated into Turkish by researchers and Turkish-English language experts, and expert opinion was taken for Turkish-English compatibility. Two pilot studies were conducted to evaluate children's participation in the task and following the instructions. Seventy children attending pre-school education institutions participated in the study. Children are asked to complete the unfinished stories presented through a scene and figures. The coders evaluated the video-recorded children's narratives using a detailed rating system. In addition, teachers evaluated the social skills and problem behaviors of children. The results affirmed that the friendship dimensions were conceptually related to each other and the inter-coder reliability was high. Furthermore, our findings indicate that the story completion method on the basis of the narratives of children is a comprehensive and developmentally appropriate way to assess children's friendships.
The Balearic Islands in ‘Island Encyclopaedias’, 700 BCE–1700 CE: An historical and archaeological assessment of island knowledge production with suggestions for future research
Authors: Dierksmeier Laura , Cespa Stefano
Published: April 2022

Historical ‘island encyclopaedias’ (isolarii, islarios, ‘de insulis’) and their predecessors (Nesiotikà, peripli) were predominately written by authors of the Mediterranean region from the 7th century BCE to the 17th century CE. In this article, we first present an overview of these sources geared towards an Island Studies readership and next consider two main questions: First, how was knowledge about islands produced in the past? And second, can these historical sources motivate new questions for future research? The Balearic Islands have been selected to investigate these questions due to their long history of settlements and trade networks, which prompted their inclusion in many encyclopaedias. In addition, local archaeological and historical sources permit a comparison of emic and etic perspectives. Topics of analysis include descriptions of geography, cultural customs and resource use (including oil, wine, animals, salt, and freshwater), each selected with a view to future comparative studies.
Can we scale Digital Twins of Nature-based Solutions for stormwater and transboundary water security projects?
Authors: Brasil José Artur Teixeira , de Macedo Marina Batalini , de Oliveira Thalita Raquel Pereira , Ghiglieno Filippo Giovanni , de Souza Vladimir Caramori Borges , Marinho e Silva Gabriel , Gomes Júnior Marcus Nóbrega , de Souza Felipe Augusto Arguello , Mendiondo Eduardo Mario
Published: April 2022

Nature-based Solutions (NbS) are presented as an alternative and decentralized solutions with different application scales for problems addressed to urban expansion as water quality reduction and floods. The usage of control strategies and mathematical modeling techniques has shown promising results for optimizing hydraulic and water treatment processes. The Digital Twins (DT) as process integration technology are widely used in industry, and recently these technique usages in urban water systems are showing effective results in both management and planning. However, there is a lack of proper literature definition for DT applied to NbS, especially for stormwater and transboundary water security projects. Thus, this paper sought through a literature review to access the existing conceptual challenges and the DT definition as a framework, identify how the mathematical modeling reported in the literature can improve the DT development, and evaluate the potential benefits associated with the application of DT in NbS.
Gravimetric selection of activated sludge for settling properties improvement and granular sludge formation – full scale case study
Authors: Gemza N. , Kuśnierz M.
Published: April 2022

With an increasing frequency of extreme weather events wastewater treatment plant operators face a need to increase plant hydraulic capacity while continuing to comply with effluent quality requirements. An economically attractive way to meet this challenge is to significantly improve secondary settling tank performance and therefore assure safe wet weather plant operation. The objective of this study was to evaluate gravimetric selection technology conducted in hydrocyclones as a way for improving activated sludge settling characteristics in continuous flow BNR with a long sludge retention time and assess its ability to form granular sludge. Long term operational data and sludge morphology monitoring data were analysed. A significant drop in sludge volume index (SVI) (to values under 50 ml/g) and increase in return activated sludge solids concentration (to values above 20 g/L) was observed. Hydrocyclone installation consistently, selectively retained denser, larger flocs in the system and after a start-up phase large granules begin to appear. Gravimetric selection did not prevent the seasonal filamentous biomass outgrowth and temperature drop at the beginning of winter resulted in rapid rise of SVI and SST sludge blanket height especially after heavy rain. Technology under study proved to be effective under certain process conditions but it needs further research to consistently maintain low SVI values throughout the whole year.
Construction of g-C3N4/Ag/TiO2 Z-scheme photocatalyst and Its improved photocatalytic U(VI) reduction application in water
Authors: Liu Yuelin , Yuan Yilei , Ni Shangyuan , Liu Jun , Xie Shuibo , Liu Yingjiu
Published: April 2022

The reduction of soluble U(VI) to insoluble U(IV) by photocatalytic technology is considered to be a valid method to remove U(VI) from water. Herein, g-C3N4/Ag/TiO2 Z-scheme heterojunction was synthesized for photocatalytic U(VI) reduction application. The SEM, XRD and XPS characterization results showed that a ternary g-C3N4/Ag/TiO2 composite photocatalyst was synthesized successfully. g-C3N4/Ag/TiO2 exhibited excellent photocatalytic reduction performance for U(VI) under visible light irradiation. After 30 min irradiation, the removal rate of U(VI) was above 99%. XPS indicated that the majority of U(VI) on the surface of g-C3N4/Ag/TiO2 was reduced to U(IV). In addition, the photocatalytic activity of g-C3N4/Ag/TiO2 has been kept significantly after five rounds of experiments, indicating good stability. g-C3N4/Ag/TiO2 exhibited better photocatalytic reduction of U(VI) under visible light irradiation, which is mainly ascribed to Z-scheme photocatalytic mechanism assisted by the LSPR effect (Local Surface Plasmon Resonance). Ag with plasmon resonance effect on the loading has a strong absorption of photon energy. In addition, an intermediate charge transfer channel is formed between Ag and the semiconductor to inhibit the combination of photogenerated electrons and holes, resulting in a significant increase in the photocatalytic activity of the photocatalyst. This idea has some significance in design of other composite photocatalytic systems.
Complicações psicológicas na saúde mental e os benefícios da atividade física: uma revisão da literatura durante a pandemia de COVID-19
Authors: Rivello Cukier Majlech , França Rivello Guimarães da Silva Marina , Bárbara Batista Silveira
Published: April 2022

A disseminação mundial da COVID-19 alterou a normalidade da vida diária, forçando a população ao distanciamento e isolamento social e desencadeou problemas psicológicos, como transtorno do pânico, ansiedade e depressão. O principal objetivo deste estudo é relatar a prevalência e gravidade deste sofrimento psicológico, avaliar a saúde mental atual na sociedade e, portanto, construir uma intervenção relevante, como a atividade física, para lidar com este desafio de forma eficiente. Foi realizada uma revisão da literatura com o instrumento de busca PICO. Para a seleção dos artigos em português e inglês entre 2019 e 2021, seguindo os critérios de inclusão e exclusão, foi utilizada a base de dados PubMed para ampliar a busca. Apenas dois artigos relataram sintomas psicológicos entre pacientes com COVID-19. O primeiro estudo mostrou que o sintoma de estresse pós-traumático estava presente em 96,2% de 714 pacientes hospitalizados, mas estáveis. O segundo estudo mostrou que a prevalência de depressão (29,2%) foi elevada (p = 0,016) entre 57 pacientes recém-recuperados de COVID-19 em comparação com os participantes em quarentena (9,8%), enquanto nenhuma diferença no nível de ansiedade foi encontrada (P = 0,154). Dois artigos revelaram menor bem-estar psicológico em comparação com antes do COVID-19. No entanto, um estudo não encontrou diferença significativa nos sintomas de ansiedade, depressão ou estresse. Portanto, manter uma rotina regular de exercícios é uma estratégia fundamental para a saúde física e mental durante um período de descanso forçado, como a atual emergência de coronavírus.
Violência obstétrica
Authors: Souza Maria Cristina Almeida de , Porfírio Laila Monteiro
Published: April 2022

A violência obstétrica (VO) é um termo utilizado para caracterizar as ações violentas que ocorrem durante a prática profissional na assistência obstétrica. Se no momento do parto a mulher torna-se vítima da violência obstétrica, podem ocorrer transtornos psicológicos, justificando, assim, a necessidade da presença de um psicólogo para o suporte à vítima. O objetivo desta pesquisa foi analisar o conhecimento dos estudantes de um curso de graduação em psicologia de uma Universidade Privada sobre a VO. Estudo quantitativo, transversal, amostra por conveniência, não probabilística, constituída pelos alunos de Psicologia. Dados coletados por meio de um questionário eletrônico. Participaram da pesquisa 41,87% dos alunos. Do total de participantes, 84,3% informaram saber o significado de VO. Quando perguntados sobre a não permissão à parturiente para ficar na posição de sua preferência e a negativa à presença do acompanhante escolhido na hora do parto, respectivamente 71,6% e 91% dos participantes concordou ser VO. Na percepção de 71,6%, restrição à movimentação da mulher em trabalho de parto configura VO, assim como também, para 91,8% dos participantes, se enquadra neste tipo de violência a indução à realização de cesariana.  Informações em linguagem pouco acessível à parturiente, na opinião de 88,8% dos estudantes, representa VO, bem como a estimulação à complementação de fórmulas em detrimento ao aleitamento materno exclusivo. Concluiu-se que os participantes possuem conhecimento sobre VO. Mas ainda há déficits de conhecimento, que poderá comprometer prática profissional, sinalizando que esta pesquisa poderá contribuir para atualização de conteúdos programáticos disciplinares.
Violência Obstétrica: a dor que tem cor e gênero
Authors: Brandão Tamires Maria Neves , De Mello Andrade Maria Clara
Published: April 2022

O presente trabalho tem como objetivo geral trazer uma reflexão crítica às práticas assistenciais do parto, buscando apontar como a “violência obstétrica” se apresenta, tendo como objetivo especifico explicar como ela alimenta outros tipos de discriminações como a de gênero e a racial, e como a informação pode contribuir para que os direitos dessas mulheres sejam preservados desde a gestação até o puerpério. Bem como discorrer sobre as relações de poder sobre o corpo da mulher, as medidas de prevenção da violência obstétrica apresentadas pelo governo brasileiro e algumas contradições, e as possibilidades de enfrentamento dessa violência. Como metodologia utilizou-se a revisão de literatura especializada no tema, por meio de buscas em periódicos eletrônicos, artigos, livros, cartilhas, publicações oficiais nacionais e internacionais e legislações internacionais e nacionais.
TR-NOE NMR STUDY OF THE E. COLI WILD-TYPE GAPDH AND ITS THR313 MUTANT I NAD+ COMPLEX
Authors: Eyschen Jacqueline , Corbier Catherine , Vitoux Bernard , Branlant Guy , Thong Cung Manh
Published: April 2022

10 and 20 TR-NOE and molecular dynamics simulations were used to determine the conformation of NAD+
bound to the E. coliwild-type GAPDH or to its Asn313Thr mutant. The results were consistent with syn and
anti conformations of the nicotinamide-ribose and adenine-ribose bonds, respectively, in agreement with
crystallographic data. Different koff dissociation rate constants were observed for these two complexes.
Red- and Blue-Shifting in the Circular Dichroism Spectra of Polypeptides due to Dipole Effects
Authors: Cascio M. , Wallace B.A.
Published: April 2022

The peptide transitions which give rise to the characteristic circular dichroism (CD) spectrum of a given polypeptide are influenced by environmental effects, similar to those observed in absorption spectra. The extent of the shift in the CQ spectrum was found to correlate fairly well with solvent dipole. The relative red- or blue-shifting of the transitions due to these effects have important implications concerning the interpretation of the CD spectra of polypeptides and proteins in non-aqueous solvents, such as membrane proteins.
Fmoc-L-p-Azidophenylalanine
Authors: Elliott Timothy J. , Haase Katherine L. , Jones John H.
Published: April 2022

A convenient one-pot preparation of 9-fluorenylmethoxycarbonyl-L-p-azidophenylalanine is described.
Antitumor Effects of Turmeric on OVCAR-3 Ovarian Cancer Cell Lines
Authors: Gurer Hulusi Goktug , Gursoy Ozlem Ozgur , Eren Ceren Yildiz , Sezer Canan Vejselova
Published: April 2022

Introduction:

Ovarian cancer is the deadliest gynecological malignancy, usually not detected until the late
stages. In vitro cell culture is a method used to study the behavior of cells in a controlled environment. Turmeric has
attracted the attention of scientists due to its anticancer potential.

Method:

OVCAR-3 cells were cultured in RPMI medium with 100 units/mL-100 μg/mL of penicillin-streptomycin
and 10% foetal bovine serum in a CO2 incubator. Turmeric extract was diluted in DMSO. Different concentrations of
turmeric extract were prepared. Annexin-V staining was performed to test the translocation of phosphatidylserine to the
outer side of the cell membrane as a clear indicator of apoptosis.

Results:

Turmeric extract significantly reduced the viability of OVCAR-3 cells both within 24 and 48 hours of exposure.
OVCAR-3 cells were treated with IC50 concentration of turmeric extract for 24 hours. 82.60% of cells were viable.
The percentages of the dead, early apoptotic, and late apoptotic cells were detected to be 0.80%, 9.70%, and
6.90%, respectively. Untreated OVCAR-3 cells had migration ability. OVCAR-3 cells exposed to an IC50 concentration
of turmeric extract for 24 hours did not close the scratch area.

Conclusion:

In this research, anticancer effects of turmeric have been demonstrated by different analysis methods.
Implications and Efficacy of Aromatase Inhibitors in Combination and Monotherapy
for the Treatment of Lung Cancer
Authors: Rahal Bayan A. , Bardaweel Sanaa K.
Published: April 2022

Background:

Lung tumors express high levels of aromatase enzyme compared to surrounding normal tissue.
Inhibition of aromatase has emerged as a recent therapeutic approach for the treatment of breast cancer. However,
the role of aromatase inhibition in lung cancer treatment requires further investigation.

Methods:

The anti-proliferative effects of aromatase inhibitors were evaluated by MTT assay. Cell migration was
assessed using a wound healing assay. The mechanism of cell death was determined using the annexin VFITC/
propidium iodide staining flow cytometry method. The soft agar colony formation assay evaluated cells’ capability
to form colonies.

Result:

Exemestane and curcumin significantly inhibited the growth of lung cancer cell lines in a dose- and timedependent
manner. The IC50 values after 48 hours of treatment with exemestane were 176, 180, and 120 μM in A549,
H661, and H1299, respectively. Curcumin IC50 values after 48 hours were 80, 43, and 68 μM in A549, H661, and
H1299, respectively. The combined treatment of exemestane or curcumin with cisplatin, raloxifene, and celecoxib
resulted in a synergistic effect in the A549 lung cell line with a combination index of less than 1, suggesting synergism.
Exemestane resulted in approximately 96% inhibition of wound closure at 100 μM, while curcumin resulted in approximately
63% inhibition of wound closure at 50 μM. Exemestane and curcumin inhibited the formation of cell colonies
by reducing the number and size of formed colonies of A549, H661, and H1299 cell lines in a concentration dependent
manner. Exemestane and curcumin had significantly induced apoptosis in A549 cells compared to control of untreated
cells.

Conclusion:

Aromatase inhibition by exemestane or curcumin had significantly inhibited the growth of lung cancer
cell lines, synergized with cisplatin, raloxifene, and celecoxib, suppressed lung cancer cell migratory potential, induced
apoptosis, and reduced colony formation of lung cancer cells.
practice of using corporate English in the official sector of Bangladesh
Authors: Mumu Musrat Sultana , Salehin Ananya , Kulsum Umme
Published: April 2022

The beginning of English language in Bangladesh had an agitated past as well as an indifferent but overwhelming present. Till now, Bangladesh is largely considered as a monolingual country where English is intensely important for international communication. The British people took an Action project to enhance the use of their language, which is English as a tool for better access to world employment. This was one of the biggest reasons behind establishing English as an International language of the world. In this research the researcher intends to highlight the problems and prospects of corporate English inside Bangladesh. The research sites were located at different corporate houses of Dhaka city. Both quantitative and analytical methods have been incorporated in the study in analyzing the data. Based on these, some proposals have been made to create awareness and to minimize the problems of using English at the corporate level of the employees.
Signalement van Het verdriet van Spanje. Een natie op zoek naar zichzelf / Christiane Stallaert
Authors: Van Campenhout Nico
Published: April 2022

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Joris Van Severen en Paul Kenis, flaminganten getekend door de Grote Oorlog
Authors: De Wever Bruno
Published: April 2022

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Recensie van Drieman / Wide Vercnocke
Authors: Van Campenhout Nico
Published: April 2022

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Recensie van: Jan Peumans, een zachte anarchist / Wim Peumans
Authors: Verdoodt Frans-Jos
Published: April 2022

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Vlaamse beweging in tijden van corona
Authors: De Wever Bruno
Published: April 2022

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Recensie van: Hugo in de jungle. Herinneringen aan een politieke pennenridder / Gaston Durnez
Authors: Van Campenhout Nico
Published: April 2022

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Hoe taal België kraakt, de toekomst van Brussel bepaalt en debatten over variëteiten aanjaagt
Authors: De Wever Bruno
Published: April 2022

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Структурные свойства твердых растворов GaInAsSbBi, выращенных на подложках GaSb
Authors: Пащенко А.С. , Девицкий О.В. , Лунин Л.С. , Лунина М.Л. , Пащенко О.С.
Published: April 2022

GaInAsSbBi solid solutions with different Bi contents are synthesized on n-GaSb substrates with a misorientation of 6° between the (100) and (111)A planes. Structural properties and morphology of GaInAsSbBi thin films are studied. Transmission electron microscopy and X-ray diffraction have shown that the films have a polycrystalline structure. It is found that an increase in the Bi concentration in the solid solution leads to a decrease in the average size of the region of coherent scattering by (111) reflection from 20 to 5 nm. It is shown that in films with a lower content of Bi, the thickness of the transition amorphous layer at the “layer-substrate” heterointerface decreases.
Social Determinants in Self-Protective Behavior Related to COVID-19: Association Rule–Mining Study
Authors: Urbanin Gabriel , Meira Wagner , Serpa Alexandre , Costa Danielle de Souza , Baldaçara Leonardo , da Silva Ana Paula , Guatimosim Rafaela , Lacerda Anísio Mendes , Oliveira Eduardo Araújo , Braule Andre , Romano-Silva Marco Aurélio , da Silva Antônio Geraldo , Malloy-Diniz Leandro , Pappa Gisele , Miranda Débora Marques
Published: April 2022

Background

Human behavior is crucial in health outcomes. Particularly, individual behavior is a determinant of the success of measures to overcome critical conditions, such as a pandemic. In addition to intrinsic public health challenges associated with COVID-19, in many countries, some individuals decided not to get vaccinated, streets were crowded, parties were happening, and businesses struggling to survive were partially open, despite lockdown or stay-at-home instructions. These behaviors contrast with the instructions for potential benefits associated with social distancing, use of masks, and vaccination to manage collective and individual risks.

Objective

Considering that human behavior is a result of individuals' social and economic conditions, we investigated the social and working characteristics associated with reports of appropriate protective behavior in Brazil.

Methods

We analyzed data from a large web survey of individuals reporting their behavior during the pandemic. We selected 3 common self-care measures: use of protective masks, distancing by at least 1 m when out of the house, and handwashing or use of alcohol, combined with assessment of the social context of respondents. We measured the frequency of the use of these self-protective measures. Using a frequent pattern–mining perspective, we generated association rules from a set of answers to questions that co-occur with at least a given frequency, identifying the pattern of characteristics of the groups divided according to protective behavior reports.

Results

The rationale was to identify a pool of working and social characteristics that might have better adhesion to behaviors and self-care measures, showing these are more socially determined than previously thought. We identified common patterns of socioeconomic and working determinants of compliance with protective self-care measures. Data mining showed that social determinants might be important to shape behavior in different stages of the pandemic.

Conclusions

Identification of context determinants might be helpful to identify unexpected facilitators and constraints to fully follow public policies. The context of diseases contributes to psychological and physical health outcomes, and context understanding might change the approach to a disease. Hidden social determinants might change protective behavior, and social determinants of protective behavior related to COVID-19 are related to work and economic conditions.

Trial Registration

Not applicable.
Designing Tangibles to Support Emotion Logging for Older Adults: Development and Usability Study
Authors: Gooch Daniel , Mehta Vikram , Stuart Avelie , Katz Dmitri , Bennasar Mohamed , Levine Mark , Bandara Arosha , Nuseibeh Bashar , Bennaceur Amel , Price Blaine
Published: April 2022

Background

The global population is aging, leading to shifts in health care needs. In addition to developing technology to support physical health, there is an increasing recognition of the need to consider how technology can support emotional health. This raises the question of how to design devices that older adults can interact with to log their emotions.

Objective

We designed and developed 2 novel tangible devices, inspired by existing paper-based scales of emotions. The findings from a field trial of these devices with older adults are reported.

Methods

Using interviews, field deployment, and fixed logging tasks, we assessed the developed devices.

Results

Our results demonstrate that the tangible devices provided data comparable with standardized psychological scales of emotion. The participants developed their own patterns of use around the devices, and their experience of using the devices uncovered a variety of design considerations. We discuss the difficulty of customizing devices for specific user needs while logging data comparable to psychological scales of emotion. We also highlight the value of reflecting on sparse emotional data.

Conclusions

Our work demonstrates the potential for tangible emotional logging devices. It also supports further research on whether such devices can support the emotional health of older adults by encouraging reflection of their emotional state.
Risk Factors Associated With SARS-CoV-2 Breakthrough Infections in Fully mRNA-Vaccinated Individuals: Retrospective Analysis
Authors: Liu Cong , Lee Junghwan , Ta Casey , Soroush Ali , Rogers James R , Kim Jae Hyun , Natarajan Karthik , Zucker Jason , Perl Yehoshua , Weng Chunhua
Published: April 2022

Background

COVID-19 messenger RNA (mRNA) vaccines have demonstrated efficacy and effectiveness in preventing symptomatic COVID-19, while being relatively safe in trial studies. However, vaccine breakthrough infections have been reported.

Objective

This study aims to identify risk factors associated with COVID-19 breakthrough infections among fully mRNA-vaccinated individuals.

Methods

We conducted a series of observational retrospective analyses using the electronic health records (EHRs) of the Columbia University Irving Medical Center/New York Presbyterian (CUIMC/NYP) up to September 21, 2021. New York City (NYC) adult residences with at least 1 polymerase chain reaction (PCR) record were included in this analysis. Poisson regression was performed to assess the association between the breakthrough infection rate in vaccinated individuals and multiple risk factors—including vaccine brand, demographics, and underlying conditions—while adjusting for calendar month, prior number of visits, and observational days in the EHR.

Results

The overall estimated breakthrough infection rate was 0.16 (95% CI 0.14-0.18). Individuals who were vaccinated with Pfizer/BNT162b2 (incidence rate ratio [IRR] against Moderna/mRNA-1273=1.66, 95% CI 1.17-2.35) were male (IRR against female=1.47, 95% CI 1.11-1.94) and had compromised immune systems (IRR=1.48, 95% CI 1.09-2.00) were at the highest risk for breakthrough infections. Among all underlying conditions, those with primary immunodeficiency, a history of organ transplant, an active tumor, use of immunosuppressant medications, or Alzheimer disease were at the highest risk.

Conclusions

Although we found both mRNA vaccines were effective, Moderna/mRNA-1273 had a lower incidence rate of breakthrough infections. Immunocompromised and male individuals were among the highest risk groups experiencing breakthrough infections. Given the rapidly changing nature of the SARS-CoV-2 pandemic, continued monitoring and a generalizable analysis pipeline are warranted to inform quick updates on vaccine effectiveness in real time.
Consciousness, Analytic Idealism and Buddhist Foundations: Exploring Non-Materialist Ways of Connecting Eastern and Western Spiritual Perspectives
Authors: Hyland Prof Terry
Published: April 2022

Contemporary approaches to explaining the connections and reconciling perceived differences between spiritual and scientific interpretations of reality have tended to accept mainstream interpretations of physics, cosmology and biology. The resultant putative combinations of ideas-seeking to equate materialist with non-materialist worldviews-display anomalous, artificial and deeply problematic features. Instead of accepting the validity of scientific materialism-expressed in accounts offered, for instance, by Thich Nhat Hanh, the Dalai Lama, and, in a more secular context, Deepak Chopra and Fritjof Capra-the central thesis of this paper is that it is more plausible to question the foundations of materialism and argue for an idealist interpretation of both science, reality and spirituality as suggested in recent work by Bernardo Kastrup, Steve Taylor and Donald Hoffman. After exploring the central claims of these new interpretations of idealism-and their principal critiques of scientific materialism-arguments that such perspectives offer a richer, more cogent and more parsimonious method of linking Eastern and Western worldviews than the flawed materialist perspectives will be explained and justified.
Empirical Analysis on Influencing Factors of Financial Revenue in Sichuan Province
Authors: Gan Mingli
Published: April 2022

Fiscal revenue is an important means of macroeconomic regulation and control of the country. It is the financial guarantee to perform and realize government functions. It can effectively allocate resources and income distribution, and then help the stable and healthy development of national economy. According to the relevant data of Sichuan Province from 2000 to 2020, four explanatory variables, namely fiscal expenditure, regional GDP, tax revenue and fixed asset investment, are selected to construct a multiple regression model. Using Eviews10.0, the multiple regression model is estimated, tested and corrected. The empirical results show that the change of fiscal revenue in Sichuan Province is mainly affected by tax revenue and fixed asset investment. Finally, combined with the analysis results, suggestions are put forward for the fiscal revenue growth and economic development of Sichuan Province.
A Study of the Extension of the China-Pakistan Economic Corridor to Afghanistan in the Context of the Taliban’s Return to Power: A Response from Sichuan
Authors: Yang Xiuqin , Guo Ling
Published: April 2022

On August 15, 2021, the Taliban overthrew the Ghani government and returned to power. The Afghan Taliban government’s ability to govern and its foreign policy are still unclear. China, as a neighboring country of Afghanistan, has always been friendly with the Afghan people and has no historical hatred. As a neighbor of Afghanistan, China can play a constructive role in the smooth transition of the situation in Afghanistan by taking advantage of being a neighbor. China-Pakistan Economic Corridor (CPEC) is a key mechanism for China to develop China-Afghanistan economic and trade relations. The China-Pakistan Economic Corridor has achieved remarkable results in Pakistan. With the return of the Taliban to power and the return of calm in Afghanistan after the U.S. withdrawal, the extension of the China-Pakistan Economic Corridor to Afghanistan has become a common goal promoted by China, Afghanistan and Pakistan. However, it remains to be seen where the Taliban government returns to power, and the international community is cautious about its attitude. On March 30-31, 2022, Chinese State Councilor and Foreign Minister Wang Yi hosted the third meeting of foreign ministers of Afghanistan’s neighbors in Tunxi, Anhui Province, attended by the foreign ministers or representatives of Pakistan, Iran, Russia, Tajikistan, Turkmenistan, and Uzbekistan. Wang Yi also hosted the “Afghanistan Neighbors + Afghanistan” Foreign Ministers’ Dialogue and invited Acting Foreign Minister Mottaki of the Taliban government to attend. This is a new starting point for China-Afghanistan cooperation and friendship. Sichuan can take advantage of its distance and infrastructure to contribute to the Sino-Afghan friendship.
Creencias de las educadoras acerca de la evaluación de sus alumnos preescolares: un estudio de caso
Authors: Gomez Patiño Raúl , Seda Santana Ileana
Published: April 2022

Este trabajo presenta resultados de una investigación más amplia en el tema. Se revisa literatura pertinente y se precisa la metodología de la investigación. Los resultados sugieren la presencia de creencias contrastantes sobre la evaluación: 1) la evaluación cualitativa y formativa, 2) la evaluación cuantitativa que es la que reconocen los padres, y 3) la evaluación con exámenes. Se discute que, a pesar de prevalecer creencias compatibles con la visión de la evaluación curricular, parecen prevalecer creencias de una evaluación tradicional porque es la que evidencia el aprendizaje de los niños y reconocen los padres. Se concluye que estas visiones pueden ser el resultado de los retos que implican para las educadoras autentificar los aprendizajes mediante la aproximación cualitativa de la evaluación.
colegialidad invisible en la educación básica
Authors: Sánchez Vázquez María Alejandra , Nishikawa Aceves Antonieta Kiyoko
Published: April 2022

En este artículo se discute la problemática que suscita la reciente política en educación básica, sobre formación docente en colectivos escolares. Se plantea que al promover esta nueva política se ha comprendido parcialmente el cambio de paradigmas del aprendizaje, de una versión individualista a la versión social o situada. La discusión remite a la revisión de los fundamentos de la teoría del aprendizaje situado, al concepto de comunidades de práctica y, tangencialmente, al de colegios invisibles. Se argumenta que la comprensión parcial de la realidad escolar y una interpretación teórica falaz del aprendizaje situado pueden afectar la implementación de la nueva política de formación. Se concluye que sería acertado reconocer, en el discurso oficial, que el germen de la colegialidad existe en toda comunidad escolar y que éste habrá de ser considerado para fortalecer la colegialidad en cada colectivo escolar.
Posmodernidad y universidad: ¿una reflexión necesaria?
Authors: Lampert Ernâni
Published: April 2022

El estudio aborda una problemática compleja, actual y polémica, que tiene repercusión directa en la dimensión pedagógica de la universidad y, consecuentemente, afecta la calidad de la enseñanza universitaria. En la primera parte, el autor analiza en profundidad y de acuerdo con diversos autores, el término posmodernidad, que es tan amplio como contradictorio. Caracteriza el megaparadigma posmoderno a partir de estudios literarios y de otras áreas del conocimiento. En la segunda parte analiza la universidad como principal gestora de ciencia, que debido a los cambios ocurridos en las últimas décadas es consciente de que le falta un paradigma que le sirva de ancla, y por ello se siente muy cuestionada, ya que, aun reconociendo que existan excepciones, no logra atender las exigencias de una sociedad cada vez más competitiva. Termina, a título de reflexión, con algunas consideraciones.
Simulation of Boost Derived Hybrid Converter Using Fuzzy Logic Controller for EV Application
Authors: Isverya A. S. , Jamna Dr. A.
Published: April 2022

Abstract: A new control technique for hybrid converter topologies with a single DC input that simultaneously supplies DC and AC to appropriate DC and AC loads is presented in this paper. This is achieved by using Voltage Source Inverter (VSI) bridge instead of single step-up switch in a boost converter. This converter is known as Boost Derived Hybrid Converter (BDHC) because it is derived from the basic boost converter. Unipolar sinusoidal pulse width modulation (PWM) is used to control the BHDC. This BDHC utilizes less number of switches and furnishes DC and AC yield with higher reliability. Fuzzy logic controllers (FLC) are being used to replace the conventional PID controllers in this control technique. Since fuzzy controller is the best option for non-linear control technique, it is used to control BDHC which is has nonlinear dynamics. The input to the fuzzy logic controller is error and change in error from two different comparators which contrasts AC and DC voltages with their respective reference voltages. The simulation results of BDHC are done using MATLAB/SIMULINK. Keywords: Boost Derived Hybrid Converter (BDHC), Voltage Source Inverter (VSI), Pulse Width Modulation (PWM), Fuzzy Logic Controller (FLC)