bluuebunny/crossref_metadata_2025 huggingface dataset:
Second‐order state‐specific multireference Møller Plesset perturbation theory: Application to energy surfaces of diimide, ethylene, butadiene, and cyclobutadiene
Authors: Mahapatra Uttam Sinha , Chattopadhyay Sudip , Chaudhuri Rajat K.
Published: August 2010

The complete active space spin‐free state‐specific multireference Møller‐Plesset perturbation theory (SS‐MRMPPT) based on the Rayleigh‐Schrödinger expansion has proved to be very successful in describing electronic states of model and real molecular systems with predictive accuracy. The SS‐MRMPPT method (which deals with one state while using a multiconfigurational reference wave function) is designed to avoid intruder effects along with a balanced description of both dynamic and static correlations in a size‐extensive manner, which allows us to produce accurate potential energy surfaces (PESs) with a correct shape in bond‐breaking processes. The SS‐MRMPPT method is size consistent when localized orbitals on each fragment are used. The intruder state(s) almost inevitably interfere when computing the PESs involving the breaking of genuine chemical bonds. In such situations, the traditional effective Hamiltonian formalism often goes down, so that no physically acceptable solution can be obtained. In this work, we continue our analysis of the SS‐MRMPPT method for systems and phenomena that cannot be described either with the conventional single‐reference approach or effective Hamiltonian‐based traditional MR methods. In this article, we investigate whether the encouraging results we have obtained at the SS‐MRMPPT level in the study of cis‐trans isomerization of diimide (N2H2), ethylene (C2H4), and 1,3‐butadiene (C4H6) carry over to the study of chemical reactions. The energy surfaces of the double‐bond flipping interconversion of the two equivalent ground and two lowest singlet state structures of cyclobutadiene have also been studied. All results have been discussed and assessed by comparing with other state‐of‐the‐art calculations and corresponding experimental data whenever available. © 2010 Wiley Periodicals, Inc. J Comput Chem, 2011
Benign prostatic hyperplasia: Evaluation of T1, T2, and microvascular characteristics with T1‐weighted dynamic contrast‐enhanced MRI
Authors: Kershaw Lucy E. , Hutchinson Charles E. , Buckley David L.
Published: August 2010

Purpose

To evaluate microvascular and relaxation parameters of prostate and nearby muscle in patients with benign prostatic hyperplasia (BPH), and to examine measurement reproducibility.

Materials and Methods

In this prospective study, 13 patients with BPH were imaged twice prior to surgery. The imaging protocol included a three‐dimensional (3D) inversion‐recovery turbo field‐echo measurement of T1, a multiecho measurement of T2, and a high temporal resolution (1.5 seconds per volume) dynamic contrast‐enhanced (DCE) acquisition. The DCE data were analyzed using a distributed parameter tracer kinetics model to provide estimates of perfusion (Fb), extraction fraction (E), mean transit time (Tc), and extravascular‐extracellular volume (ve) in both the central gland (CG) and the peripheral zone (PZ) of the prostate, and in nearby muscle. Precision of these estimates was calculated using a bootstrap technique and the reproducibility was evaluated using the within‐patient coefficient of variation (wCV).

Results

The microvascular parameters were estimated in the prostate with high precision; in particular, E, Fb, and ve had median CVs of ≤6%, ≤4 %, and ≤5%, respectively. Reproducibilities of the T1 and T2 measurements were excellent (wCV ≤ 4%), and reproducibility of the other parameters reflected values seen in previous studies.

Conclusion

Microvascular and relaxation properties of BPH can be measured precisely with reproducibilities for a distributed parameter tracer kinetics model that are comparable to those for a simpler model. Measurements of T1 and T2 were highly reproducible. J. Magn. Reson. Imaging 2009;29:641–648. © 2009 Wiley‐Liss, Inc.
Automated frame‐by‐frame endocardial border detection from cardiac magnetic resonance images for quantitative assessment of left ventricular function: Validation and clinical feasibility
Authors: Corsi Cristiana , Veronesi Federico , Lamberti Claudio , Bardo Dianna M.E. , Jamison Ernest B. , Lang Roberto M. , Mor‐Avi Victor
Published: August 2010

Purpose

To develop a technique based on image noise distribution for automated endocardial border detection from cardiac magnetic resonance (CMR) images throughout the cardiac cycle, validate it, and test its clinical utility.

Materials and Methods

Images obtained in 36 patients were analyzed using custom software to obtain left ventricular (LV) volume throughout the cardiac cycle, end‐systolic and end‐diastolic LV volumes, and ejection fraction (EF). Validation against manually‐traced endocardial boundaries included intertechnique comparisons of LV volumes, slice areas, and border positions. Then, the clinical feasibility of the dynamic automated analysis of LV function was tested in 14 patients with normal LV function, 12 patients with systolic dysfunction, and 10 patients with diastolic dysfunction.

Results

Analysis time for one cardiac cycle was <15 minutes. Intertechnique comparisons resulted in high correlation (r > 0.96), small biases (volumes: –6 mL; EF: 4.6%) and narrow limits of agreement (volumes: 17.6 mL; EF: 9.2%). We found significant intergroup differences in multiple quantitative indices of systolic and diastolic function.

Conclusion

Fast, automated, dynamic detection of LV endocardial boundaries is feasible and allows accurate quantification of LV size and function, which is potentially clinically useful for objective assessment of systolic and diastolic dysfunction. J. Magn. Reson. Imaging 2009;29:560–568. © 2009 Wiley‐Liss, Inc.
Endoscopic Coblator™‐assisted management of encephaloceles
Authors: Smith Ncholas , Riley Kristen O. , Woodworth Bradford A.
Published: August 2010

Objectives:

Numerous studies have demonstrated the efficacy and safety of endoscopic management of cerebral spinal fluid (CSF) rhinorrhea, encephaloceles, and anterior skull base defects. Techniques have evolved as new instrumentation has developed, but typically involve meticulous bipolar cautery to decrease the potential for intracranial bleeding. The present study evaluated the Coblator™ as a novel tool in transnasal endoscopic management of encephaloceles.

Study Design:

Outcomes study.

Methods:

A prospective cohort involving 19 patients with 22 encephaloceles (19 spontaneous, 3 traumatic) reduced with the Coblator™ (radiofrequency coblation plus bipolar modality) was compared to a retrospective cohort of six encephaloceles (five spontaneous, one traumatic) removed with endoscopic bipolar cautery. Main outcome measures included duration of encephalocele removal and bleeding events. Bleeding encountered during removal was considered a minor event unless more than one attempt at cauterization was required. Other data collected included standard demographics, encephalocele size, and complications.

Results:

Average duration of coblation‐assisted encephalocele removal was 15.8 minutes compared to 46 minutes with standard bipolar cautery (P = .0003). Average number of bleeding episodes did not significantly differ between groups (Coblator™, 1.0 ± 1.57 vs. bipolar, 1.17 ± 0.98; P = .80). One episode of major bleeding occurred in the coblation group when an anterior ethmoid artery was encountered during removal. Encephalocele size was similar between groups (Coblator™, 17.4 mm vs. bipolar, 16.6 mm; P = .65).

Conclusions:

Radiofrequency coblation significantly increased intraoperative speed during encephalocele removal with similar hemostatic properties when compared to bipolar cautery alone and represents a useful instrument in the management of encephaloceles. Laryngoscope, 2010
In‐training assessment and predictors of competency in endoscopic sinus surgery
Authors: Laeeq Kulsoom , Waseem Raafeh , Weatherly Robert A. , Reh Douglas D. , Lin Sandra Y. , Lane Andrew P. , Ishii Masaru , Cummings Charles W. , Bhatti Nasir I.
Published: August 2010

Objectives:

To evaluate the reliability and validity of the assessment tool for endoscopic sinus surgery when used in the operating room for in‐training assessment of operative competency; to identify the tasks that may serve as the best indicators for overall surgical performance.

Study Design:

Cross‐sectional validation study.

Methods:

We implemented the global and checklist parts of the endoscopic sinus surgery (ESS) assessment tool to evaluate the surgical skills of 13 Otolaryngology–Head & Neck Surgery residents (PGY 1–5) in the operating room over a period of 15 months. Rhinology faculty scored residents' performance of every step of ESS at the end of each procedure using a previously validated tool. Construct validity was calculated by comparing scores across training levels (using analysis of variance [ANOVA]). Regression analysis was performed to identify tasks on the ESS checklist that most strongly correlated to the overall surgical performance.

Results:

Construct validity was demonstrated with senior residents performing better than junior residents. Average checklist and global scores improved with the number of days on rhinology rotation. “Identification of uncinate and boundaries” was found to be the strongest predictor of overall surgical performance.

Conclusions:

The results indicate that this evaluation tool is a reliable and valid instrument for the assessment of surgical competency in the operating room. It can be used to identify weak areas of performance for which additional training may be required early in the rotation/training. Laryngoscope, 2010
Pathological laughter in Gilles de la Tourette syndrome: An unusual phonic tic
Authors: Cavanna Andrea E. , Ali Fizzah , Leckman James F. , Robertson Mary M.
Published: August 2010

Patients with Gilles de la Tourette syndrome (GTS) can display socially inappropriate behaviors as part of their multiform tic phenomenology. Pathological laughter (PL), defined as the presence of episodic and contextually inappropriate outbursts of laughter, has been detailed as a symptom of various psychiatric and neurological conditions. We present a case series of eight subjects diagnosed with GTS who reported PL as part of their tic repertoire. All subjects experienced PL as a simple phonic tic, accompanied by characteristic premonitory urges and significant impairment in social interactions. In addition, all patients presented with multiple tic‐related symptoms (mainly self‐injurious behaviors and echolalia, n = 7; palilalia, n = 6; coprolalia/mental coprolalia, n = 5), and six patients had comorbid conditions (in particular obsessive‐compulsive disorder/behaviors, n = 7; attention‐deficit hyperactivity disorder, n = 4). We suggest that the pathophysiological mechanisms underlying the expression of PL as a tic could involve a dissociation between frontostriatal and limbic networks. © 2010 Movement Disorder Society.
The Self‐Stigma of Depression Scale (SSDS): development and psychometric evaluation of a new instrument
Authors: Barney Lisa J. , Griffiths Kathleen M. , Christensen Helen , Jorm Anthony F.
Published: August 2010

Self‐stigma may feature strongly and be detrimental for people with depression, but the understanding of its nature and prevalence is limited by the lack of psychometrically‐validated measures. This study aimed to develop and validate a measure of self‐stigma about depression. Items assessing self‐stigma were developed from focus group discussions, and were tested and refined over three studies using surveys of 408 university students, 330 members of a depression Internet network, and 1312 members of the general Australian public. Evaluation involved item‐level and bivariate analyses, and factor analytic procedures. Items performed consistently across the three surveys. The resulting Self‐Stigma of Depression Scale (SSDS) comprised 16 items representing subscales of Shame, Self‐Blame, Social Inadequacy, and Help‐Seeking Inhibition. Construct validity, internal consistency and test–retest reliability were satisfactory. The SSDS distinguishes self‐stigma from perceptions of stigma by others, yields in‐depth information about self‐stigma of depression, and possesses good psychometric properties. It is a promising tool for the measurement of self‐stigma and is likely to be useful in further understanding self‐stigma and evaluating stigma interventions.Copyright © 2010 John Wiley & Sons, Ltd.
In vitro effects of Echis carinatus venom on the human plasma proteome
Authors: Guerranti Roberto , Cortelazzo Alessio , Hope‐Onyekwere Nnadozie S. , Furlani Emiliano , Cerutti Helena , Puglia Michele , Bini Luca , Leoncini Roberto
Published: August 2010

Echis carinatus venom (EV) is a complex mixture of toxins that contribute to its lethality. EV proteolytic activity was analyzed by zymography, chromogenic assays, and SDS‐PAGE. To understand the molecular mechanism of the envenomation, we investigated the in vitro effect of EV on human plasma proteins. We looked for EV protein substrates and their proteolytic fragments. We analyzed EV proteolytic activity on standard proteins such as prothrombin or fibrinogen. To set up the optimal EV:plasma protein ratio conditions, plasma was incubated with EV (treated plasma), depleted of abundant proteins, and subjected to SDS‐PAGE. Samples from control and treated plasma were also analyzed by 2‐DE/MALDI‐TOF MS, leading to the identification of four classes of plasma proteins cleaved by EV: proteases, protease inhibitors, binding proteins, and transporters. EV mainly proteolyzes entire proteins but can also act on physiological fragments. In summary, the physiological effects of EV proteases involve other important processes in addition to blood coagulation; complement activation and hemoglobin metabolism are also affected. In particular, the cleavage of protease inhibitors appears to be the mechanism through which the venom neutralizes the body's defenses.
Vibrations of tetrahedral Co and Cu clusters on a Cu(111) surface
Authors: Borisova Svetlana D. , Eremeev Sergey V. , Rusina Galina G. , Chulkov Evgueni V.
Published: August 2010

Vibrational properties of tetrahedral clusters of Cu and Co on the Cu(111) surface are studied by using interatomic interaction potentials constructed within tight‐binding second moment approximation. It was shown that interaction of the Co4 and Cu4 clusters with the substrate leads to arising of frustrated translation and frustrated rotation in‐plane polarized vibrational modes localized on the cluster atoms. The vibrational modes of the free Cu4 cluster upon its adsorption on the Cu(111) surface mix with Cu bulk phonons and become almost delocalized. Contrary to that, in the Co4 cluster on the surface the high frequency modes remain strongly localized and mixed with the nearest neighbor atoms vibrations. The highest frequency vibration of the Co4 cluster splits due to different interaction with certain groups of nearest neighbor atoms (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Thermodynamic properties of Au–Pd nanostructured surfaces studied by atomic scale modelling
Authors: Atanasov Ivailo , Hou Marc
Published: August 2010

We address the question of the sensitivity of the segregation and ordering properties to the surface energy of Au‐Pd alloys and nanoalloys. To this purpose, the parameterization of an EAM potential fitted to the vacancy formation energy was modified in order to predict surface energies closer to the experimentally measured ones. Metropolis Monte Carlo sampling was used to predict segregation and ordering. We show in the detail that modifying the surface energies of Au and Pd by up to 50 percent and, their surface energy difference by about 35 percent is of no major importance for the ordering and segregation properties of nanostructured Au‐Pd alloy surfaces (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Characterization of assembled quantum dots and single‐electron transistors by photoemission and photoabsorption
Authors: Bâldea Ioan , Köppel Horst , Cederbaum Lorenz S.
Published: August 2010

In this work, we show that photoionization and photoabsorption can be valuable experimental tools to characterize regular quantum‐dot nanoarrays and nanoelectronic devices.

For exemplification, we present results obtained by exact numerical diagonalization for nanorings consisting of metallic quantum dots and single‐electron transistors based on semiconducting quantum dots (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Design and preliminary results of a DNA chip for the detection of microorganisms in water samples
Authors: Martins Nelson , Vale Filipa F. , Vieira Helena
Published: August 2010

Waterborne pathogens are responsible for several diseases, either due to the consumption of contaminated drinking water or due to the contact with polluted recreational waters. There is an increasing awareness that emergent and viral pathogens should also be monitored for determining water quality. Conventional detection methodologies present several shortcomings, such as reliance in indicator species, low throughput and increasing resources as more species are to be detected. DNA chips have the potential to serve as surveillance systems for the simultaneous detection of pathogens, overcoming these limitations. In the present study, a rapid method for the detection of multiple waterborne pathogens (bacteria and viruses) was developed, using a DNA chip (AQUACHIP®). Species and group specific probes were implemented on a DNA chip, both for mandatory and non‐mandatory microorganisms. Considerations regarding the AQUACHIP® design (probe layout, replicates and dilutions), DNA labelling and amplification, and preliminary results of the application of the chip for the detection of E. coli DNA are presented (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Experimental design for determination of effective parameters in hydrothermal synthesis of TiO2‐derived nanotubes
Authors: Safaei M. , Sarraf‐Mamoory R. , Rashidzadeh M. , Manteghian M.
Published: August 2010

In this paper, a screening approach, involving the use of Plackett‐Burman experimental design, permitted the evaluation of the effects of 8 parameters from hydrothermal synthesis of TiO2 derived nanotubes such as raw materials surface area, m, filling factor, temperature, time, aging, stirring, and HCl concentration on the surface area of products. The study highlights the role of filling factor, stirring, temperature, raw materials, and time conditions on surface area of responses.

TEM micrographs showed that the morphologies for high, medium, and low surface areas of products are nanotubes, nanowires, and nanospheres, respectively. The N2 adsorption‐desorption isotherms and pore size distributions showed that with decreasing surface area, the area of the hysteresis loops and gas volumes of N2 adsorbed are decreased. Also, the hysteresis loops shift to the region of higher relative pressure. Therefore, An increase in average pore size and a decrease in pore volume reduced surface area of product (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Initial growth stages of AlF3 on Cu(100): an STM study
Authors: Moreno‐López J. C. , Passeggi M. C. G. , Ruano G. , Vidal R. A. , Ferrón J.
Published: August 2010

In this study we present results concerning the early growth stages of an insulator‐metal interface by means of scanning tunnelling microscopy. In particular, we report the growth of aluminium fluoride (AlF3) islands over a Cu (100) surface at room temperature, from sub‐monola‐yer coverages up to 1.25 monolayers. These islands cover the substrate with a single monolayer film up to depositions of 0.80 monolayers, with 3D growth beyond this coverage. High voltages (V ≥ 2.50 V) are needed to obtain STM images, showing the insulator character of the AlF3 islands. Important modifications are observed in the AlF3/Cu (100) surface after an annealing treatment. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Initial concentration and fluidic effects on the dielectrophoretic trapping of DNA
Authors: Loucaides N. G. , Ramos A. , Georghiou G. E.
Published: August 2010

In this paper the effect of initial particle concentration on the dielectrophoretic trapping of particles is investigated. The numerical simulations incorporate the effects of the suspension motion due to the presence of the electric field and the steric particle effect.

It is found that the initial concentration has a significant impact on both the initial rate and steady state of particle collection and subsequently the trapping range is also affected (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Conduction and electroluminescence from organic continuous and nanofiber thin films
Authors: Kjelstrup‐Hansen Jakob , Liu Xuhai , Henrichsen Henrik H. , Thilsing‐Hansen Kasper , Rubahn Horst‐Günter
Published: August 2010

In this work, the electrical and electroluminescence properties of para‐hexaphenylene (p6P) thin films and nanofibers have been investigated in a field‐effect transistor device configuration with interdigitated source‐drain bottom contact electrodes. P‐type behavior of thin films is observed with a mobility of 1×10‐6 cm2/Vs and a threshold voltage around ‐30 V. AC gated devices show electroluminescence for both thin films and stamped nanofibers even when the drain electrode is floating. This suggests either hole and electron injection from the same electrode or impact ionization. The highest electroluminescence intensity is observed from thin film FETs with a 2.5 µm source‐drain gap. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Nonrelativistic CI calculations for B+, B, and B− ground states
Authors: Almora‐Díaz César X. , Bunge Carlos F.
Published: August 2010

State of the art configuration interaction (CI) techniques are used to obtain the best possible nonrelativistic CI results for B+, B, and B− ground states using energy‐optimized basis sets of 252, 294, and 294 radial Slater‐type functions, respectively. For positive boron, E(B+) = −24.348861 + ΔEbie = −24.348883(1) a.u.(B) with a basis set incompleteness error ΔEbie = −0.000022(1), in good agreement with the latest exponentially correlated Gaussian (ECG) result of −24.348883 a.u.(B) of Komasa et al. (Phys Rev A, 2002, 65, 042507). For neutral B, E(B) = −24.653837 −0.000024(2) = −24.653861(2), which is the most accurate ab initio estimate and lies slightly below a recent (not fully optimized) ECG result of −24.653840 a.u.(B) of Bubin et al (J Chem Phys, 2009, 131, 044128). For negative boron, E(B−) = −24.664014 −0.000024(2) to which an energy error of −0.000001 must be added to give −24.664039(2), which is the first fully correlated ab initio result. Comparison with experimental values of ionization energy and electron affinity must await the results of corresponding relativistic calculations, in progress. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2010
Seed‐to‐seed potential allelopathic effects between Ligularia virgaurea and native grass species of Tibetan alpine grasslands
Authors: Zhang Shiting , Liu Junpeng , Bao Xiaohui , Niu Kechang
Published: August 2010

Allelopathy is an important process in plant communities, but the role of seed allelopathy in natural ecosystems remains poorly understood. In the present study, we examined the potential allelopathic effects of Ligularia virgaurea (a dominant species in degraded Tibetan grasslands) seeds on the germination of four native grass species (Festuca sinensis, Agrostis gigantean, Bromus inermis, and Elymus nutans). The results showed that L. virgaurea seeds can have potential allelopathic effects on seed germination, mean time to germination and root growth rates of native grass species. We further demonstrate that these effects are driven by a water‐soluble seed leachate. Species with smaller seeds were generally more sensitive than larger seeded species. The results suggest that seed‐to‐seed allelopathic potential may be an important mechanism driving the dominance of L. virgaurea in degraded alpine grasslands on the Tibetan Plateau. Further studies are required to demonstrate effects of seed‐to‐seed potential allelopathy in a field setting.
Thromboembolic Complications following Spine Surgery Assessed with Spiral CT Scans
Authors: Kim Han Jo , Walcott-Sapp Sarah , Adler Ronald S. , Pavlov Helene , Boachie-Adjei Oheneba , Westrich Geoffrey H.
Published: August 2010

Spine surgery is associated with a significant risk of postoperative pulmonary embolism (PE) and/or deep vein thrombosis (DVT). The goal of this study was to determine which symptoms and risk factors were associated with spiral CT scans positive for PE and/or DVT in the postoperative spine surgery patient. We conducted a retrospective review of all spine patients who underwent a postoperative CT to rule out PE during the period of March 2004–February 2006. The type of surgical procedure, risk factors, symptoms prompting scan ordering, anticoagulation, and treatment were recorded. Logistic regression models were used to determine significant predictors of a positive CT in this patient population. Of the 3,331 patients that had spine surgery during the study period, 130 (3.9%) had a spiral CT scan to rule out PE and/or proximal DVT. Thirty-three of the 130 (25.4%) CT scans were positive for PE only, five (3.8%) for PE and DVT, and three (2.3%) for DVT only. Only 24.5% (32) patients had risk factors for thromboembolic disease, and of these, a history of PE and/or DVT was the only significant risk factor for a positive scan ( p = 0.03). No presenting symptoms or demographic variables were noted to have a significant association with PE and/or DVT. The type of surgical procedure (i.e., anterior, posterior, and percutaneous) was not associated with an increased risk for PE and/or DVT. Patients who are undergoing spine surgery with a history of thromboembolic disease should be carefully monitored postoperatively and may benefit from more aggressive prophylaxis.
National identification of Dutch youth: An exploratory study☆
Authors: Oppenheimer Louis
Published: August 2010

246 Dutch participants aged 8, 10, 12, 14, and 16 years were presented with the Strength of Identification Scale (SoIS; Barrett, 2007) and the National Identity scale based on Cultural and Historical achievements (NICH; derived from the NATID, Keillor & Hult, 1999). The study aimed to examine the extent and nature of Dutch children and adolescents’ identification with The Netherlands and to explore whether changes in aspects of national identification are evident across age. Already at age 8 years children identify themselves with the Dutch nation and with increasing age national identification becomes primarily determined by the extent that participants consider themselves to be Dutch and show positive affect towards the Dutch nation. Identification on the basis of cultural and historical achievements of the Dutch people became less evident following the age of 10 years although Dutch historical and cultural achievements contributed significantly to the extent of national identification.
PeriAnesthesia Nursing Core Curriculum
Authors: Schirmer Sandra
Published: August 2010

PeriAnesthesia Nursing Core Curriculum Lois Schick and Pamela E. Windle 2nd edition 2010, Saunders 1488 pages, $89.95 softcover
Is Marketing Academia Losing Its Way? Linking with Practitioners
Authors: Sweeney Jillian C.
Published: August 2010

Reibstein et al. (2009) view that the needs of industry and the efforts of academia represents a growing gap and identify some “researchable topics” that would help fill this gap. In this article I discuss the considerable amount of well known research already undertaken in the four identified areas, which offers an excellent grounding for extending these research streams further. While not agreeing with all points in their article, I believe that their article is provocative and timely, prompting academics to reflect on their research priorities. I also discuss the needs of industry that I identified in Western Australia and how a top down approach is needed to reduce this industry-academia gap.
Molecular determinants of the interactions between SRC‐1 and LXR/RXR heterodimers
Authors: Son You Lee , Lee Young Chul
Published: August 2010

MINT‐7986822, MINT‐7986848, MINT‐7986865: SRC1 (uniprotkb:Q15788) binds (MI:0407) to RXR (uniprotkb:P19793) by pull down (MI:0096)
Detection of Tritrichomonas foetus in cats in Greece
Authors: Xenoulis Panagiotis G. , Saridomichelakis Manolis N. , Read Sarah A. , Suchodolski Jan S. , Steiner Jörg M.
Published: August 2010

Intestinal infection of cats with Tritrichomonas foetus has been reported in the USA, Canada, several European countries, and Australia. However, T foetus has not been previously reported in cats in Greece. The aim of this study was to test fecal samples from cats living in Greece for the presence of T foetus DNA. Feces were collected from 31 cats living in Greece. DNA was extracted from the fecal samples and the presence of T foetus DNA was detected by a single-tube nested polymerase chain reaction (PCR). T foetus specific DNA was detected in the feces of 6/30 (20.0%) cats. All six cats were reported to have normal fecal quality at the time of sample collection and five of them were adults. The present study confirms for the first time the presence of T foetus in cats in Greece and suggests that T foetus infection is often asymptomatic in older cats.
Anesthesia Oral Board Review
Authors: Lovich-Sapola Jessica A.
Published: August 2010

The accreditation process for anesthesia in the United States is considered one of the most difficult in all medical specialties, with residents required to pass both an oral and written exam to gain certification. This book is specially designed for the American Board of Anesthesiology Oral Examination. The evidence-based approach is presented in a concise outline-oriented format, with an emphasis on test results and visual images. The Knockout Treatment Plan demonstrates the correct method of managing the case to the satisfaction of the examiners, while the Technical Knockout sections give additional tips for successfully passing the examination. The straightforward format of this book makes it suitable not only as an oral review book but also as an introduction to anesthesia rotations for medical students, medical interns, and nurse anesthetist students; furthermore, the book can be used as a technical study guide for anesthesia residents. More than 100 topics in this book have already been board-review tested by residents.
Taxation and Governmental Finance in Sixteenth-Century Ming China
Authors: Huang Ray
Published: August 2010

Originally published in 1974, this is a detailed study of the financial administration of the Chinese government during the Ming dynasty (1368–1644), with particular attention to the sixteenth century, a topic about which very little has been published either in Chinese or any Western language. Professor Huang has worked through an enormous quantity and variety of source material - in particular the 133 substantial volumes of the Ming Veritable Records - and has compared the documents on financial matters with the entries in local gazetteers. The complicated workings of government finance present great difficulties to all specialists in Chinese financial and administrative history and in different branches of local Chinese history from the fifteenth century onwards. Professor Huang's study will provide all such researchers with an authoritative work of reference.
The Syntax of Welsh
Authors: Awbery G. M.
Published: August 2010

This is a full-length study of a Celtic language from the standpoint of modern linguistic theory. Dr Awbery particularly discusses a topic - the passive form of the verb - which has itself been of central interest in previous work on transformational grammar. She is thus able to test certain tenets of transformational theory against data from a previously unconsidered language. The results are significant, and argue clearly for a separation of syntactic and semantic analysis; constructions which are related syntactically are shown to have no necessary semantic relation, and the type of description which can reveal one set of relationships is not able to reveal the other. The book is therefore a contribution both to linguistic theory and to the study of the Welsh language. Each step in the argument is carefully explained and documented, and no prior knowledge of Welsh is assumed.
Non-K-exact uniform Roe C*-algebras
Authors: Špakula Ján
Published: August 2010

We prove that uniform Roe C*-algebras C*uX associated to some expander graphs X coming from discrete groups with property (τ) are not K-exact. In particular, we show that this is the case for the expander obtained as Cayley graphs of a sequence of alternating groups (with appropriately chosen generating sets).
THE INFLUENCE OF GERMAN STATE-THEORY ON THE DESIGN OF THE AUSTRALIAN CONSTITUTION
Authors: Aroney Nicholas
Published: August 2010

This article draws attention to an important but neglected story about the dissemination of German and Swiss state-theories among English-speaking scholars in the second half of the 19th century and the influence of these ideas on those who designed and drafted the Australian Constitution. In particular, the article focuses upon the theories of federalism developed by the Swiss-born scholar, Johann Caspar Bluntschli, and the Saxon-born Georg Jellinek, and explains their influence, via the British historian, Edward A Freeman, and the American political scientist, John W Burgess, upon the framers of the Australian Constitution. The story is important because it illustrates the way in which constitutional ideas can be transmitted from one social and political context into a very different one, undergoing significant, though often subtle, modifications and adaptations in the process. The story is also important because it sheds light on the way in which the framers of the Australian Constitution came to conceive of the kind of federal system that they wished to see created. The story seems to have been overlooked, however, not only due to a general neglect of the intellectual history of the Australian Constitution, but also due to the assumption that prevailing Australian political and legal ideas were of Anglo-American provenance. While this assumption generally holds true, a closer examination of the intellectual context of Australian federalism reveals a surprisingly significant German influence on the framers of the Australian Constitution.
THE EFTA COURT 15 YEARS ON
Authors: Fredriksen Halvard Haukeland
Published: August 2010

For over 15 years, the reports of the EEA Agreement's imminent demise have proven to be greatly exaggerated. In this article it is argued that a great deal of the credit for this accomplishment is due to the EFTA Court. Through a distinctly dynamic approach to the Agreement, the EFTA Court has been able to convince an initially sceptical ECJ that the goal of extending the internal market to include the EFTA States is actually achievable. For the EFTA States, the consequence is a more ‘supranational’ EEA Agreement than originally conceived. Further, it is shown that the EFTA Court appears, in hard cases, to lean even further towards teleological (ie integrationist) interpretation than the ECJ. It is suggested that this may be due to to structural imbalances between the two EEA courts, the EFTA Court's desire to prove its independence from the EFTA States and its quest for recognition from the ECJ.
Pliny,Letters5.10 and the Literary Career of Suetonius
Authors: Power Tristan J.
Published: August 2010

This paper establishes a new date for the publication of Suetonius’Illustrious Menthrough allusions to Suetonius’Virgilin Pliny,Letters5.10. These allusions are part of a much wider network of allusions, both within this particular letter and more generally in Pliny's Book 5, that revolves around the theme of unpublished writings. It is a partial or full publication of theIllustrious Menthat probably led to Suetonius’ award of theius trium liberorumina.d.110, and he may now have published all of theCaesarsbefore his dismissal by Hadrian ina.d.122.
An Anglo-Saxon runic coin and its adventures in Sweden
Authors: Clunies Ross Margaret
Published: August 2010

In the years 1741–3, two scholars of Anglo-Saxon and Gothic, one an
Englishman and the other a Swede, were engaged in correspondence. The
Englishman was the Reverend Edward Lye (1694–1767), then rector of
Yardley Hastings in Northamptonshire, and the Swede was Eric Benzelius the
Younger (1675–1743), bishop of Linköping and, in the last year of his life,
archbishop-elect of Uppsala. For many years Benzelius had been preparing an
edition of the ‘Codex Argenteus’ of the Gothic gospels, which had been in
Uppsala University Library since 1669, but he had been unable to complete the
work on account of his many other commitments and also through the lack of
suitable publishers for such a volume in Sweden. In his frustration, he sought
the help of his many highly-placed friends in England, who included Sir Hans
Sloane and John Carteret, first Earl Granville, a former Ambassador to
Sweden. They directed him to Edward Lye as the only man in England competent
to complete the edition, and the University Press at Oxford, as the only
publisher able to handle the diffcult commission, as it still possessed Junius's
type fonts for printing Gothic, Old English and runic characters.
Memorials incognito: the candle, the drain and the cabbage patch for Diana, Princess of Wales
Authors: Sully Nicole
Published: August 2010

In the second half of the twentieth century, the growing recognition of the plurality of history and the constructive nature of monuments, in conjunction with a more general realisation of the intellectual problems of war, resulted in a widespread interrogation – both intellectually and aesthetically – of concepts of memorialisation and commemoration. This interrogation is credited as the catalyst for a series of new approaches to monument-making, famously exemplified by Maya Lin's Vietnam Veterans Memorial in Washington (1982) in addition to a series of holocaust-related memorials, such as those theorised in the seminal writings of James E. Young. These memorials, in conjunction with post-modern discussions of the politics of memory and issues of counter-memory, complicated the culture of commemoration, seeing the emergence of new commemorative types known as counter-monuments, which Young defines as ‘memorial spaces conceived to challenge the very premise of the monument’. These are often also identified by terms such anti-memorials or progressive memorials. Among these, new sub-genres also emerged in response to particular methods of commemoration such as living and spontaneous memorials, in addition to more gestural methods of commemoration involving, for example, services or performances that transcend the categories of sculpture and architecture.
Lines and words on display: Alvin Boyarsky as a collector, curator and publisher
Authors: Marjanović Igor
Published: August 2010

In 1983, the Architectural Association (AA) School of Architecture mounted an exhibition of Zaha Hadid's work titled Planetary Architecture II. An image from this event shows Hadid as she points to one of the drawings on the wall surrounded by a group of listeners. The interior is saturated with drawings. As they unfold before the viewer, the drawings blur the boundaries between walls, floors and ceiling. An interior space wrapped in drawing, orchestrated by the exhibitor, the image of this show is nevertheless also an expression of the pedagogical ideas of Alvin Boyarsky, the chairman of the AA school between 1971 and 1990.
Quantifying the concentration of ferrimagnetic particles in sediments using rock magnetic methods
Authors: Lascu Ioan , Banerjee Subir K. , Berquó Thelma S.
Published: August 2010

We have developed a quantification method that uses mainly room temperature rock magnetic measurements to calculate concentrations of ferrimagnetic particles in sediments. Our method uses saturation magnetization (Ms) as a total ferrimagnetic concentration proxy, the saturation remanence ratio (Mrs/Ms) as a magnetic grain‐size proxy, the anhysteretic remanence ratio (χa/Mrs) to estimate inter‐particle magnetostatic interactions, and the normalized susceptibility of the ferrimagnetic fraction (χf/Ms) to calculate the proportion of ultrafine, superparamagnetic particles. This approach eliminates the effect of dilution of the magnetic properties by weakly magnetic matter, and allows the calculation of direct concentrations (or fluxes for dated sedimentary profiles) of constituent ferrimagnetic components. We test our method on a short sediment core from an urban Minnesota lake, for which we calculate ferrimagnetic fluxes of four magnetic components, and compare their pre‐ and post‐European settlement values. Our quantification technique can be applied for reconstructing past environmental changes in a range of sedimentary environments, and is particularly useful for large sets of samples, where detailed magnetic unmixing methods are unfeasible due to time or instrument constraints.
Dispersers shape fruit diversity in
Ficus
(Moraceae)
Authors: Lomáscolo Silvia B. , Levey Douglas J. , Kimball Rebecca T. , Bolker Benjamin M. , Alborn Hans T.
Published: August 2010

Seed dispersal by vertebrates is one of the most common and important plant–animal mutualisms, involving an enormous diversity of fruiting plants and frugivorous animals. Even though plant reproduction depends largely on seed dispersal, evolutionary ecologists have been unable to link co-occurring traits in fruits with differences in behavior, physiology, and morphology of fruit-eating vertebrates. Hence, the origin and maintenance of fruit diversity remains largely unexplained. Using a multivariate phylogenetic comparative test with unbiased estimates of odor and color in figs, we demonstrate that fruit traits evolve in concert and as predicted by differences in the behavior, physiology (perceptive ability) and morphology of their frugivorous seed dispersers. The correlated evolution of traits results in the convergence of general appearance of fruits in species that share disperser types. Observations at fruiting trees independently confirmed that differences in fig traits predict differences in dispersers. Taken together, these results demonstrate that differences among frugivores have shaped the evolution of fruit traits. More broadly, our results underscore the importance of mutualisms in both generating and maintaining biodiversity.
Different functions of the C
3
HC
4
zinc RING finger peroxins PEX10, PEX2, and PEX12 in peroxisome formation and matrix protein import
Authors: Prestele Jakob , Hierl Georg , Scherling Christian , Hetkamp Stefan , Schwechheimer Claus , Isono Erika , Weckwerth Wolfram , Wanner Gerhard , Gietl Christine
Published: August 2010

The integral peroxisomal membrane proteins PEX10, PEX2, and PEX12 contain a zinc RING finger close to the C terminus. Loss of function of these peroxins causes embryo lethality at the heart stage in
Arabidopsis
. Preventing the coordination of Zn
2+
ions by amino acid substitutions in PEX10, PEX2, and PEX12 and overexpressing the resulting conditional sublethal mutations in WT uncovered additional functions of PEX10. Plants overexpressing ΔZn-mutant PEX10 display deformed peroxisomal shapes causing diminished contact with chloroplasts and possibly with mitochondria. These changes correlated with impaired metabolite transfer and, at high CO
2
, recoverable defective photorespiration plus dwarfish phenotype. The N-terminal PEX10 domain is critical for peroxisome biogenesis and plant development. A point mutation in the highly conserved TLGEEY motif results in vermiform peroxisome shape without impairing organelle contact. Addition of an N-terminal T7 tag to WT PEX0 resulted in partially recoverable reduced growth and defective inflorescences persisting under high CO
2
. In contrast, plants overexpressing PEX2-ΔZn-T7 grow like WT in normal atmosphere, contain normal-shaped peroxisomes, but display impaired peroxisomal matrix protein import. PEX12-ΔZn-T7 mutants exhibit unimpaired import of matrix protein and normal-shaped peroxisomes when grown in normal atmosphere. During seed germination, glyoxysomes form a reticulum around the lipid bodies for mobilization of storage oil. The formation of this glyoxysomal reticulum seemed to be impaired in PEX10-ΔZn but not in PEX2-ΔZn-T7 or PEX12-ΔZn-T7 plants. Both cytosolic PEX10 domains seem essential for peroxisome structure but differ in metabolic function, suggesting a role for this plant peroxin in addition to the import of matrix protein via ubiquitination of PEX5.
Evidence of Coulomb blockade behavior in a quasi-zero-dimensional quantum well on TiO
2
surface
Authors: Meunier Vincent , Pan M. H. , Moreau F. , Park K. T. , Plummer E. W.
Published: August 2010

Line defects on the surface of rutile TiO
2
(110) form in pairs separated by 1.2 nm creating a quantum well. The well is effectively closed by the presence of two charged structures at both ends separated by a distance in the 10–20 nm range. As expected for quantum confinement a long period oscillatory feature of the local density of states is observed and attributed to the formation of discrete quantum states inside the system. It is at first glance surprising that the lowest energy quantum state of the well can be observed at room temperature. The properties of the quantum state cannot be explained in an independent-electron, band-like theory. Instead, electron-electron correlation must be included to give a satisfactory picture of the spatial distribution of the charge density. Theory predicts charging energies of 1.30 eV and 1.14 eV for quantum well lengths of 14 nm and 16 nm, respectively, in good agreement with a classical calculation and the size dependence of the capacitance. This observation opens up the possibility of experimentally imaging the transition from a Coulomb blockade localized in a zero-dimensional system to an independent-particle or band-like behavior in an extended one-dimensional system.
γ-Tubulin regulates the anaphase-promoting complex/cyclosome during interphase
Authors: Nayak Tania , Edgerton-Morgan Heather , Horio Tetsuya , Xiong Yi , De Souza Colin P. , Osmani Stephen A. , Oakley Berl R.
Published: August 2010

A cold-sensitive γ-tubulin allele of Aspergillus nidulans, mipAD159, causes defects in mitotic and cell cycle regulation at restrictive temperatures that are apparently independent of microtubule nucleation defects. Time-lapse microscopy of fluorescently tagged mitotic regulatory proteins reveals that cyclin B, cyclin-dependent kinase 1, and the Ancdc14 phosphatase fail to accumulate in a subset of nuclei at restrictive temperatures. These nuclei are permanently removed from the cell cycle, whereas other nuclei, in the same multinucleate cell, cycle normally, accumulating and degrading these proteins. After each mitosis, additional daughter nuclei fail to accumulate these proteins, resulting in an increase in noncycling nuclei over time and consequent inhibition of growth. Extensive analyses reveal that these noncycling nuclei result from a nuclear autonomous, microtubule-independent failure of inactivation of the anaphase-promoting complex/cyclosome. Thus, γ-tubulin functions to regulate this key mitotic and cell cycle regulatory complex.
Multi-netclust: an efficient tool for finding connected clusters in multi-parametric networks
Authors: Kuzniar Arnold , Dhir Somdutta , Nijveen Harm , Pongor Sándor , Leunissen Jack A.M.
Published: August 2010

Summary: Multi-netclust is a simple tool that allows users to extract connected clusters of data represented by different networks given in the form of matrices. The tool uses user-defined threshold values to combine the matrices, and uses a straightforward, memory-efficient graph algorithm to find clusters that are connected in all or in either of the networks. The tool is written in C/C++ and is available either as a form-based or as a command-line-based program running on Linux platforms. The algorithm is fast, processing a network of > 106 nodes and 108 edges takes only a few minutes on an ordinary computer.

Availability:  http://www.bioinformatics.nl/netclust/

Contact:  jack.leunissen@wur.nl

Supplementary information:  Supplementary data are available at Bioinformatics online.