bluuebunny/crossref_metadata_2025 huggingface dataset:
IPTEKS PENGENDALIAN SISTEM INFORMASI AKUNTANSI PENJUALAN PADA PT. HASJRAT ABADI CABANG MANADO
Authors: Tuhuteru Gloria , Tirayoh Victorina Z
Published: June 2019

PT Hasjrat Abadi is an exclusive distributor for Toyota and Yamaha. This automotive company are preferred in eastern Indonesia. With modern sales, service facilities, and access to high-tech workshops, they achieving an average sales growth of 25% over the past few years. It proves the results of implementing maximum strategy. For Hasjrat Abadi, selling is one of important thing for this business. Sales are one of the important aspects in the continuity of the company's business processes and are routine activities that occur within the company. The sales process is a routine activity that produces information, and must have good mechanism. The sales cycle can occur in cash and credit. Cash payments can received directly by the company, but credit payment can occur in a longer time with billing procedures. The theoretical basis used in this article is sales accounting information system. Company need effective control to manage company sales, and has a system created to facilitate the company in conducting sales activities, namely the sales accounting information system. This article aims to find out how the control of the sales accounting information systems at PT Hasjrat Abadi in Manado, Indonesia. Keywords : accounting information system control, sales
IPTEKS AKUNTANSI PERTANGGUNGJAWABAN PUSAT PENDAPATAN PT. BANK MANDIRI
Authors: Kumaat George Evander , Maradesa Djeini
Published: June 2019

PT. Bank Mandiri (Persero) Tbk is a state-owned company that collects funds from the public in the form of deposits and redistributes them to the community in the form of loans to improve people's lives. The majority of PT Mandiri Bank's revenues are obtained from the credit system offered. The income earned is regulated by the center of accountability in this case the revenue center. From this, the research was conducted in order to find out the application of PT Mandiri Bank's revenue centers. Assessment is carried out by applying the revenue center marketing method.Keywords : accountability, revenue center, marketing method
IPTEKS PENENTUAN KELAYAKAN KREDIT BANK PADA PT. BANK RAKYAT INDONESIA (PERSERO) TBK, KCP (KANTOR CABANG PEMBANTU) BAHU
Authors: Palilingan Kartini A.T. , Pangemanan Sifrid S.
Published: June 2019

The function of banking is to raise funds from the community and channel it to the public. In collecting funds in charge of the bank is a relationship fund and in channeling funds to the public the bank provides credit to help improve the economy and the welfare of the community. In the bank there is a credit relationship that is in charge of analyzing credit at this analytical bank that can see the feasibility and risk of bad credit.Keywords: Credit Analysis, Risk of bad credit
IPTEKS STANDAR PELAYANAN MINIMAL PADA DINAS PEKERJAAN UMUM DAN PENATAAN RUANG DAERAHPROVINSI SULAWESI UTARA.
Authors: Londo Ireine P. , Suwetja I Gede
Published: June 2019

Reform in administration of government in Indonesia have cause the occurance of a number  important and fundamental changes in governance which ultimately has implication for the implementation of public services in the region. In accordance with the provisions of article 11 and article 14 ofLaw of  Year 2004 Number 32 concerning Regional Government, Government Regulation Number 65 of 2005 concerning Guidelines for Preparation and Application of Minumum Standards Service (SPM). The Government Regulation is a reference for the Ministry / Institutions in the preparation of MSS and become reference points for the government regions in implementing SPM (MSS).Basic services in the Minimum Service Standards are compulsory government affairs that are carried out by regional Governments both Provincial and Regional Governments. Government Affairs is obligatory relating to basic services which subsequently becomes the type of SPM, one of which is  SPM in the Field Public Works. Types of Basic Services for SPM in Public Works and Spatial Planning for Provincial and District / City Governments are as follows. Provincial government : meeting the needs of bulk drinking water across districts / cities and provision of cross-regency / municipal regional domestic wastewater treatment service Keywords : Minimum Service Standards, Implementation, Government
Investigation of lipids of flax seed meal and the prospect of using it in meat dishes
Authors: Izhevska O. P.
Published: June 2019

The possibility of using a plant supplement is considered in materials of the article, namely, the seed meal of flax in the recipe for meat semi-finished products “Mazurki-Volynsky” to enrich these products with physiological-functional ingredients. Flax seeds is a valuable source of polyunsaturated fatty acids. It is rich in protein substances, balanced by the amino acid, contains insoluble and water-soluble edible fibers and phenolic compounds, in particular lignans, which have antioxidant properties. In this work, a flax seeds (FS) was obtained by using the method of “cold pressing” produced by NV “Zhytomyrbioprodukt” LLC. Fatty acid composition of lipids was determined according to GOST 30418-96. The method is based on the conversion of triglycerides of fatty acid to methyl (ethyl) esters of fatty acids and on their gas chromatic analysis. The purpose of our research was to determine from the technological point of view the expediency of introducing the flax seeds into the recipes of meat semi-finished products to enrich their health-improving ingredients. For this purpose, in studies, a complete replacement of wheat flour and a partial replacement of fat material by the use of flax seed is proposed. Thus, compared to the control, the amount of meat raw material does not change, and the change occurs only at the expense of the filler of meal. The article presents a comparative estimation of the chemical composition of the flax seeds and wheat flour, the effect of flax on the change of the lipid composition of meat semi-finished products in case of its inclusion in the recipe of products. The fatty acid composition of sorbitol lipids was investigated in comparison with the fatty acid composition of the wheat flour I flavors. It is noted that the inclusion into the recipe of meat semi-finished flax seed meal in the case of replacing wheat flour and part of the fat, enriches them with such physiological-functional ingredients as proteins with a complete amino acid composition, polyunsaturated fatty acids, edible fibers, a significant part of which are water-soluble, vitamins, micro- and macro elements, lignans. The calculation method found that the amount of protein in the experimental sample, as compared with the sample, which included wheat flour, increased by 3.69% due to the increase of protein contained in FS. Adding FS changes the qualitative composition of the lipid in exploratory samples. The calculation method found that the content of polyunsaturated fatty acids (PUFAs) increased by 12% compared with control. It should be noted that the ability of these fatty acids to oxidation, with the formation of peroxides, will affect the structural and mechanical properties of semi-finished products, which should affect the process of preparation and quality of finished products. This requires further research.
New Products Based on Spelt for Restaurant Sector
Authors: Sakhno O. S. , Hryshchuk O. O. , Furmanova Y. P. , Pavliuchenko O. S.
Published: June 2019

The spelt processed products that are presented on the Ukrainian food market have been analyzed in the paper. The comparative characteristics of chemical composition of spelt products – wholemeal flour, grits, flakes, bran – with same wheat and oat products have been investigated. Spelt flour and flakes are proposed for applying at the restaurant establishments. Authors havedeveloped technology of baked products for special dietician consumption – spelt crisp bread and spelt sweet bar as well. Spelt crisp bread contains linseed, sunflower seed, spices (cilantro, curcuma), herbs (fennel, parsley). Technology of this bread includes such operations as grinding of cleaned seeds, sifting of bran and flour, mixing of dry components, adding of kefir and water. Duration of first fermentation is 20 minutes, then rectangular shaping (5×13 cm) and drying at 80 oC during 4…5 hours, then cooling at ambient temperature near 30 min. Caloric value of spelt crisp bread is 260 kCal. Sensorial parameters of spelt crisp bread – rectangular shape, light brown colour, smooth top with inclusion of linseed and sunflower seed, pleasant taste and spicy aroma, crisp crust and thick texture. Sweet spelt bar is an example of beneficial sweets. It contains sunflower seed and pumpkin seed, nuts (walnut and almond), date, honey and sesame. Caloric value of spelt sweet bar is 220 kCal. Technology of this bread includes such operations as drying of spelt flakes at 120 oC during 2 min and further cooling, soaking of date in hot water during 3 min, removing of stone and grinding. Walnut is inspected due to the absence of walnut shell, almond is soaking for 3 hours, then parboiled and grinded. All ingredients are mixed during 5 min with honey. Then bar is rectangular shaping and served. Such bar has rectangular shape, ribbed top, crisp texture, light brown colour and intense walnut aroma.
Matias Aleksanteri Castrén ja Kalevalan ruotsinnos
Authors: Häkkinen Kaisa
Published: June 2019

Kun Elias Lönnrotin kokoama runoeepos, ns. Vanha Kalevala, ilmestyi vuonna 1835, se käänsi suomen kielen ja suomalaisen kulttuurin arvostuksen huimaan nousuun. Kalevala innosti myös maisteriopintojaan viimeistelevää, alkuaan pappisuralle aikonutta Matias Aleksanteri Castrénia suuntaamaan huomionsa suomen ja sen sukukielten tutkimukseen.

Koska alkuperäistä Kalevalaa pystyivät lukemaan vain muutamat harvat oppineiston edustajat, Suomalaisen Kirjallisuuden Seura julisti kilpailun runomuotoisen ruotsin- tai saksankielisen käännöksen aikaansaamiseksi. Tällaisia ei kuitenkaan ilmaantunut. Helsingin yliopiston suomen kielen lehtori Carl Niclas Keckman luennoi Kalevalasta ja laati siitä sanatarkan ruotsinnoksen, mutta ei runomittaista versiota. Muutaman vuoden odotuksen jälkeen Kalevalasta jo aiemmin kiinnostunut Castrén ryhtyi kääntämään eeposta. Suomalaisen Kirjallisuuden Seuran stipendiaattina hän keräsi kesällä 1839 taustatietoa ja uutta kansanperinneaineistoa Vienan Karjalassa.

Aktiivinen kääntäminen kesti noin kaksi vuotta. Käännöstyön ohella Castrén julkaisi dosentinväitöskirjan ja joitakin pienempiä tieteellisiä tutkimuksia. Kevätlukukaudella 1841 Castrén luennoi Helsingin yliopistossa Kalevalasta ja viimeisteli käännöstään. Se ilmestyi kesäkuussa 1841 ja sai hyvän vastaanoton. Esimerkiksi historiallis-vertailevan kielentutkimuksen kärkiedustajiin kuulunut Jacob Grimm perehtyi Kalevalaan ja luennoi siitä Berliinin tiedeakatemiassa Castrénin ruotsinnoksen perusteella.

Castrénin ruotsinnos avasi uusia mahdollisuuksia Kalevalaa koskevalle tieteelliselle keskustelulle, koska eepos oli nyt aiempaa merkittävästi laajempien piirien luettavissa. Tärkeä rooli tässä keskustelussa oli itse Castrénilla ja hänen Kalevala-tulkinnoillaan. Kalevalan käännöksen myötä Castrén sai pysyvän kansainvälisen maineen arvostettuna kansanperinteen ja mytologian asiantuntijana. Kirjoitus perustuu Suomalais-Ugrilaisessa Seurassa 15.2.2019 pidettyyn esitelmään.
Human capital formation by means of education
Authors: Chobitko Mykola
Published: June 2019

Subject of research – the process of formation of human capital by means of education Formation of human capital by means of education. The purpose of writing the article is to formulate theoretical approaches that determine the role of education in the formation of human capital in Ukraine. Methodology of work – system-structural and comparative analyzes (for the formation of human capital in educational institutions); monographic (when studying the problem of human capital formation and its components in Ukraine and in developed countries of the world); socio-economic analysis (in the study of the actual state of affairs of the educational system and its material security); forecasting (prospect of development of educational potential in Ukraine and its investment). The results of the work – proposed new approaches to the process of vocational guidance, the formation of an applicant who has a clear image of the future profession, a personally oriented trajectory of training and development throughout life. It is argued that the need to increase investment in human capital development in educational institutions has been proved. Conclusions – human capital, based on the intellectual abilities and talent of the individual, as well as knowledge and practical skills acquired in the process of learning, education and practical activities is the greatest value of the state. Improving the educational process will enable us to ensure proper social and economic development. We have no other option except a scientific and educational breakthrough.
RETRACTED: CDX2/mir-145-5p/SENP1 Pathways Affect LNCaP Cells Invasion and Migration
Authors: He Jin-Hua , Han Ze-Ping , Zou Mao-Xian , He Meng-Ling , Li Yu-Guang , Zheng Lei
Published: June 2019

Background/Aims: Recently, rapidly accumulating evidence has shown that microRNAs (miRNAs) are involved in human tumorigenesis, and the dysregulation of miRNAs has been observed in many cancers, including prostate cancer. miR-145-5p, an miRNA with reduced expression in prostate cancer cells, has been shown to have a tumor suppressive role in a variety of tumors. However, its underlying mechanism requires further elucidation.

Methods: A lentiviral expression vector for miR-145-5p was constructed and used to establish a stable cell line (LNCaP) expressing miR-145-5p. The cells were cultured normally and divided into the control group (control), negative control group (negative control), and test group (miR-145-5p). Inhibition of proliferation was measured by a WST-8 assay. The early apoptosis rate of cells was detected by flow cytometry. Clone formation ability was detected by a clone formation inhibition test. Cell invasion and migration capacity was detected by a Transwell assay. The relative expression levels of proteins were detected by western blotting. We constructed a nude mouse model of prostate cancer to observe the effect of miR-145-5p on the growth of transplanted tumors. TargetScan bioinformatics software was used to predict target genes regulated by miR-14-5p. ChIPBase was used to predict transcription factors with binding sites in the upstream promoter region of miR-145-5p. Quantitative reverse transcription PCR was used to detect the relative expression level of genes. A bifluorescence-reporter gene vector was constructed to confirm the regulation of target genes by miR-145-5p. We used 5′ rapid amplification of cDNA ends to confirm the transcription start site of miR-145-5p.Chromatin immunoprecipitation technology was used to detect the effect of transcription factors binding to miR-145-5p.

Results: The overexpression of miR-145-5p not only inhibited the proliferation, invasion, and migration of LNCaP cells but also promoted their early apoptosis. After overexpressing miR-145-5p, the expression of small ubiquitin-like modifier protein-specific protease 1 (SENP1), and caudal-related homeobox 2 (CDX2) protein was decreased in LNCaP cells. The transcription factor CDX2 bound to the miR-145-5p promoter region and inhibited its transcription. The transcription start site of miR-145-5p was located at a guanine residue 1,408 bp upstream of the stem-loop sequence. Upon overexpression, miR-145-5p could bind to the 3′-untranslated region of SENP1 to inhibit its translation.

Conclusion: These results suggested that CDX2 inhibits the expression of miR-145-5p, thereby relieving the inhibitory effect of miR-145-5p on the translation of SENP1 and affecting the invasion and migration of prostate cancer cells.
Drinking Warm Water Improves Growth Performance and Optimizes the Gut Microbiota in Early Postweaning Rabbits during Winter
Authors: Wang Qiangjun , Fu Wei , Guo Yao , Tang Yuhan , Du Haoxuan , Wang Meizhi , Liu Zhongying , Li Qin , An Lei , Tian Jianhui , Li Mingyong , Wu Zhonghong
Published: June 2019

Accumulating evidence indicates that cold exposure changes the composition of the gut microbiota and reduces intestinal immunity in early postweaning livestock. However, little is known about the effects of drinking warm water (WW) on gut microbiota during winter. In this study, we investigated the effects of drinking WW in winter on the growth performance and gut microbiota structure of rabbits raised in poorly insulated housing from the early postweaning period (day 46) to the subadult period (day 82). The average daily gain and feed conversion ratio in rabbits drinking WW were significantly improved compared to those of the rabbits drinking cold water (CW) during 47–58 days. In addition, rabbits drinking WW had a significantly decreased the risk of diarrhea during 71–82 days. 16S rRNA sequence analysis revealed that the alpha diversity of the cecal microbiota was not significantly different between the WW and CW groups, but significantly increased with age. The relative abundance of cecal microorganisms, such as Coprococcus spp. was considerably increased at day 70 in the group drinking WW. Correlation analysis indicated that Coprococcus spp. was negatively associated with pro-inflammatory factors. In conclusion, our results suggest that drinking WW has a positive effect on growth performance and gut microbiota in rabbits during the early postweaning stage in winter.
Levofloxacin-Associated Neurotoxicity in a Patient with a High Concentration of Levofloxacin in the Blood and Cerebrospinal Fluid
Authors: Nishikubo Masashi , Kanamori Maki , Nishioka Hiroaki
Published: June 2019

Neurotoxicity is a rare and intolerable adverse effect associated with levofloxacin therapy, whose diagnosis has mostly been reported based on medical history rather than quantitative measures in the blood. We report a 68-year-old man with levofloxacin-associated encephalopathy and myoclonus with high levels of levofloxacin in the blood and cerebrospinal fluid. After hemodialysis, these decreased, and his symptoms rapidly improved. An electroencephalogram was also normal. This case showed the concentration of levofloxacin to be clearly related to levofloxacin-associated neurotoxicity. Therefore, an estimation of its concentration may contribute to accurate diagnosis.
Antibiotic Prescribing Quality in Out-of-Hours Primary Care and Critical Appraisal of Disease-Specific Quality Indicators
Authors: Colliers Annelies , Adriaenssens Niels , Anthierens Sibyl , Bartholomeeusen Stephaan , Philips Hilde , Remmen Roy , Coenen Samuel
Published: June 2019

Outpatient antibiotic use in Belgium is among the highest in Europe. The most common reason for an encounter in out-of-hours (OOH) primary care is an infection. In this study, we assessed all consultations from July 2016 to June 2018 at five OOH services. We described antibiotic prescribing by diagnosis, calculated disease-specific antibiotic prescribing quality indicators’ (APQI) values and critically appraised these APQI. We determined that 111,600 encounters resulted in 26,436 (23.7%) antibiotic prescriptions. The APQI diagnoses (i.e., bronchitis, upper respiratory infection, cystitis, tonsillitis, sinusitis, otitis media, and pneumonia) covered 14,927 (56.7%) antibiotic prescriptions. Erysipelas (1344 (5.1%)) and teeth/gum disease (982 (3.7%)) covered more prescriptions than sinusitis or pneumonia. Over 75% of patients with tonsillitis and over 50% with bronchitis, sinusitis, and otitis media were prescribed an antibiotic. Only for otitis media the choice of antibiotic was near the acceptable range. Over 10% of patients with bronchitis or pneumonia and over 25% of female patients with an acute cystitis received quinolones. The APQI cover the diagnoses for only 57% of all antibiotic prescriptions. As 5.1% and 3.7% of antibiotic prescriptions are made for erysipelas and teeth/gum disease, respectively, we propose to add these indications when assessing antibiotic prescribing quality in OOH primary care.
High Temperature (Up to 950 °C) Sensor Based on Micro Taper In-Line Fiber Mach–Zehnder Interferometer
Authors: Liao Yun-Cheng , Liu Bin , Liu Juan , Wan Sheng-Peng , He Xing-Dao , Yuan Jinhui , Fan Xinyu , Wu Qiang
Published: June 2019

A high temperature (up to 950 °C) sensor was proposed and demonstrated based on a micro taper in-line fiber Mach–Zehnder interferometer (MZI) structure. The fiber MZI structure comprises a single mode fiber (SMF) with two micro tapers along its longitudinal direction. An annealing at 1000 °C was applied to the fiber sensor to stabilize the temperature measurement. The experimental results showed that the sensitivity was 0.114 nm/°C and 0.116 nm/°C for the heating and cooling cycles, respectively, and, after two days, the sensor still had a sensitivity of 0.11 nm/°C, showing a good stability of the sensor. A probe-type fiber MZI was designed by cutting the sandwiched SMF, which has good linear temperature responses of 0.113 nm/°C over a large temperature range from 89 to 950 °C. The probe-type fiber MZI temperature sensor was independent to the surrounding refractive index (RI) and immune to strain. The developed sensor has a wide application prospect in the fields of high temperature hot gas flow, as well as oil and gas field development.
Speech-Stimulating Substances in Autism Spectrum Disorders
Authors: Castillo María Andrea , Urdaneta Kendy Eduardo , Semprún-Hernández Neomar , Brigida Anna Lisa , Antonucci Nicola , Schultz Stephen , Siniscalco Dario
Published: June 2019

Autism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory events and immune system dysfunctions are cellular and molecular events associated with ASD. Several conditions co-occur with ASD: seizures, gastro-intestinal problems, attention deficit, anxiety and depression, and sleep problems. However, language and speech issues are key components of ASD symptoms current therapies find difficult to face. Several speech-stimulating substances have been shown to be effective in increasing speech ability in ASD subjects. The need for large clinical trials to determine safety and efficacy is recommended.
Ni-Mo Sulfide Semiconductor Catalyst with High Catalytic Activity for One-Step Conversion of CO2 and H2S to Syngas in Non-Thermal Plasma
Authors: Liu Xiaozhan , Zhao Lu , Li Ying , Fang Kegong , Wu Minghong
Published: June 2019

Carbon dioxide (CO2) and hydrogen sulfide (H2S) ordinarily coexist in many industries, being considered as harmful waste gases. Simultaneously converting CO2 and H2S into syngas (a mixture of CO and H2) will be a promising economic strategy for enhancing their recycling value. Herein, a novel one-step conversion of CO2 and H2S to syngas induced by non-thermal plasma with the aid of Ni-Mo sulfide/Al2O3 catalyst under ambient conditions was designed. The as-synthesized catalysts were characterized by using XRD, nitrogen sorption, UV-vis, TEM, SEM, ICP, and XPS techniques. Ni-Mo sulfide/Al2O3 catalysts with various Ni/Mo molar ratios possessed significantly improved catalytic performances, compared to the single-component catalysts. Based on the modifications of the physical and chemical properties of the Ni-Mo sulfide/Al2O3 catalysts, the variations in catalytic activity are carefully discussed. In particular, among all the catalysts, the 5Ni-3Mo/Al2O3 catalyst exhibited the best catalytic behavior with high CO2 and H2S conversion at reasonably low-energy input in non-thermal plasma. This method provides an alternative route for syngas production with added environmental and economic benefits.
Managing Personal Finance Literacy in the United States: A Case Study
Authors: Beck Joshua J. , Garris Richard O.
Published: June 2019

This study investigates the perspectives and impact that personal finance education had on participants in Western Pennsylvania. The researchers begin with a literature review of personal finance courses in the United States (U.S.). The U.S. housing market collapse is also discussed as a key component of the financial crisis that is often overlooked and can be partly attributed to the lack of financial literacy. The findings of this study indicate that participants want personal finance courses offered in K-12 schools and at the collegiate level. They also want personal finance elements to be co-curricular in the K-12 setting. A recommendation based on responses from participants is that co-curricular teaching of personal finance should be tied in with math courses. The participants of this study either have benefited from personal finance lessons themselves or are a strong advocate for the teaching of personal finance in the future. The financial future does also bring worry to the different generations. Generation X is more worried about the financial choices of the upcoming generations, while Millennials and Generation Z are concerned about the future of the economy and how this will affect them.
An Adaptable Train-to-Ground Communication Architecture Based on the 5G Technological Enabler SDN
Authors: Franco David , Aguado Marina , Toledo Nerea
Published: June 2019

Railway communications are closely impacted by the evolution and availability of new wireless communication technologies. Traditionally, the critical nature of railway services, the long lifecycle of rolling stock, and their certification processes challenge the adoption of the latest communication technologies. A current railway telecom trend to solve this problem is to design a flexible and adaptable communication architecture that enables the detachment of the railway services—at the application layer—and the access technologies underneath, such as 5G and beyond. One of the enablers of this detachment approach is software-defined networking (SDN)—included in 5G architecture—due to its ability to programmatically and dynamically control the network behavior via open interfaces and abstract lower-level functionalities. In this paper, we design a novel railway train-to-ground (T2G) communication architecture based on the 5G technological enabler SDN and on the transport-level redundancy technique multipath TCP (MPTCP). The goal is to provide an adaptable and multitechnology communication service while enhancing the network performance of current systems. MPTCP offers end-to-end (E2E) redundancy by the aggregation of multiple access technologies, and SDN introduces path diversity to offer a resilient and reliable communication. We carry out simulation studies to compare the performance of the legacy communication architecture with our novel approach. The results demonstrate a clear improvement in the failover response time while maintaining and even improving the uplink and downlink overall data rates.
Wearable Triband E-Shaped Dipole Antenna with Low SAR for IoT Applications
Authors: Azeez Hemin , Yang Hung-Chi , Chen Wen-Shan
Published: June 2019

This paper presents a novel design of a flexible and wearable E-shaped, multiband dipole antenna. The antenna has a low profile and is printed on a common 2 mm thick denim fabric ( ε r = 1.7 ). By installing a passively coupled rectangular patch with L-shaped cuts, the lower frequency band is supported and the bandwidth at higher frequencies is also enhanced. The antenna’s performance was observed under different deformations in free space as well as when it was placed on different parts of the human body. No significant changes in the characteristics of the frequency bands of interest were observed for the flexible antenna compared with the initial nondeformable antenna. Simulations for 10 g average specific absorption rate (SAR) at different input powers up to 250 mW were carried out considering that the antenna adheres well to the human body and there is no spacing or shielding. The obtained results show that the amount of energy absorbed by the body tissue increases by increasing the incident power.
A Novel Electrocardiogram Biometric Identification Method Based on Temporal-Frequency Autoencoding
Authors: Wang Di , Si Yujuan , Yang Weiyi , Zhang Gong , Li Jia
Published: June 2019

For good performance, most existing electrocardiogram (ECG) identification methods still need to adopt a denoising process to remove noise interference beforehand. This specific signal preprocessing technique requires great efforts for algorithm engineering and is usually complicated and time-consuming. To more conveniently remove the influence of noise interference and realize accurate identification, a novel temporal-frequency autoencoding based method is proposed. In particular, the raw data is firstly transformed into the wavelet domain, where multi-level time-frequency representation is achieved. Then, a prior knowledge-based feature selection is proposed and applied to the transformed data to discard noise components and retain identity-related information simultaneously. Afterward, the stacked sparse autoencoder is introduced to learn intrinsic discriminative features from the selected data, and Softmax classifier is used to perform the identification task. The effectiveness of the proposed method is evaluated on two public databases, namely, ECG-ID and Massachusetts Institute of Technology-Biotechnology arrhythmia (MIT-BIH-AHA) databases. Experimental results show that our method can achieve high multiple-heartbeat identification accuracies of 98.87%, 92.3%, and 96.82% on raw ECG signals which are from the ECG-ID (Two-recording), ECG-ID (All-recording), and MIT-BIH-AHA database, respectively, indicating that our method can provide an efficient way for ECG biometric identification.
A Novel Photovoltaic Virtual Synchronous Generator Control Technology Without Energy Storage Systems
Authors: Bao Guangqing , Tan Hongtao , Ding Kun , Ma Ming , Wang Ningbo
Published: June 2019

Photovoltaic virtual synchronous generator (PV-VSG) technology, by way of simulating the external characteristics of a synchronous generator (SG), gives the PV energy integrated into the power grid through the power electronic equipment the characteristics of inertial response and active frequency response (FR)—this attracts much attention. Due to the high volatility and low adjustability of PV energy output, it does not have the characteristics of a prime mover (PM), so it must be equipped with energy storage systems (ESSs) in the DC or AC side to realize the PV-VSG technology. However, excessive reliance on ESSs will inevitably affect the application of VSG technology in practical PV power plants (PV-PPs). In view of this, this paper proposes the PV power reserve control type VSG (PV-PRC-VSG) control strategy. By reducing the active power output of part of the PV-PPs, the internal PV-PPs can maintain a part of the active power up/down-regulation ability in real time, instead of relying on external ESSs. By adjusting the active reserve power of this part, the output of the PV-PPs can be controlled within a certain range, and the PV-PPs can better simulate the PM characteristics and realize the FR of the grid by combining the VSG technology. At the same time, the factors affecting the reserve ratio are analyzed, and the position of the voltage operating point in PRC mode is deduced. Finally, the simulation results show that the proposed control strategy is effective and correct.
Forecasting of Coal Demand in China Based on Support Vector Machine Optimized by the Improved Gravitational Search Algorithm
Authors: Li Yanbin , Li Zhen
Published: June 2019

The main target of the energy revolution in the new period is coal, but the proportion of coal in primary energy consumption will gradually decrease. As coal is a major producer and consumer of energy, analyzing the trend of coal demand in the future is of great significance for formulating the policy of coal development planning and driving the revolution of energy sources in China. In order to predict coal demand scientifically and accurately, firstly, the index system of influencing factors of coal demand was constructed, and the grey relational analysis method was used to select key indicators as input variables of the model. Then, the kernel function of SVM (support vector machine) was optimized by taking advantage of the fast convergence speed of GSA (gravitational search algorithm), and the memory function and boundary mutation strategy of PSO (particle swarm optimization) were introduced to improve the gravitational search algorithm, and the improved GSA (IGSA)–SVM prediction model was obtained. After that, the effectiveness of IGSA–SVM in predicting coal demand was further proven through empirical and comparative analysis. Finally, IGSA–SVM was used to forecast China’s coal demand in 2018–2025. According to the forecasting results, relevant suggestions about coal supply, consumption, and transformation are put forward, providing scientific basis for formulating an energy development strategy.
A Multi-Objective Optimization Model for the Design of Biomass Co-Firing Networks Integrating Feedstock Quality Considerations
Authors: San Juan Jayne Lois G. , Aviso Kathleen B. , Tan Raymond R. , Sy Charlle L.
Published: June 2019

The growth in energy demand, coupled with declining fossil fuel resources and the onset of climate change, has resulted in increased interest in renewable energy, particularly from biomass. Co-firing, which is the joint use of coal and biomass to generate electricity, is seen to be a practical immediate solution for reducing coal use and the associated emissions. However, biomass is difficult to manage because of its seasonal availability and variable quality. This study proposes a biomass co-firing supply chain optimization model that simultaneously minimizes costs and environmental emissions through goal programming. The economic costs considered include retrofitting investment costs, together with fuel, transport, and processing costs, while environmental emissions may come from transport, treatment, and combustion activities. This model incorporates the consideration of feedstock quality and its impact on storage, transportation, and pre-treatment requirements, as well as conversion yield and equipment efficiency. These considerations are shown to be important drivers of network decisions, emphasizing the importance of managing biomass and coal blend ratios to ensure that acceptable fuel properties are obtained.
The Influence of Chemical Structure and the Presence of Ascorbic Acid on Anthocyanins Stability and Spectral Properties in Purified Model Systems
Authors: Levy Rachel , Okun Zoya , Shpigelman Avi
Published: June 2019

The loss of color pigment is an important quality factor of food products. This work aimed to systematically study, in purified model systems, the influence of anthocyanins’ structure (by increasing the size of the conjugated sugar) and the presence of ascorbic acid on their stability and spectral properties during storage at two pH levels relevant to medium and high acid foods (6.5 and 4.5, respectively). Anthocyanins (cyanidin (Cy), cyanidin 3-O-β-glucoside (Cy3G) and cyanidin 3-O-β-rutinoside (Cy3R)) displayed first-order degradation rates, presenting higher stability in acidic medium and enhanced stability with increasing size of conjugated sugar. The addition of ascorbic acid resulted in significantly enhanced degradation. Changes in ultra violet visible (UV-VIS) spectral properties presented a decrease in typical color intensity and pointed towards formation of degradation products. Identification and kinetics of formation for cyanidin degradation products were obtained by high performance liquid chromatography system-mass spectrometry (HPLC-MS).
Investor Attention and Stock Market Activities: New Evidence from Panel Data
Authors: Padungsaksawasdi Chaiyuth , Treepongkaruna Sirimon , Brooks Robert
Published: June 2019

Using the panel vector autoregression (VAR) method, this paper documents relationships between investor attention and stock market activities; i.e., return, volatility, and trading volume, respectively. In sum, bidirectional dynamic interdependence of the SVI–stock market activities relationship exists, in which the SVI–trading volume relationship shows the strongest evidence. This is consistent with prior literature using trading volume as a proxy of investor attention. However, the relationships in the developed and developing markets are statistically significantly different. The stock markets in the developed markets over-react more to the search volume than those in the developing markets. We postulate that investor attention is one of the key elements in asset pricing in stock markets.
Simplification and Detection of Outlying Trajectories from Batch and Streaming Data Recorded in Harsh Environments
Authors: Pulshashi Iq Reviessay , Bae Hyerim , Choi Hyunsuk , Mun Seunghwan , Sutrisnowati Riska Asriana
Published: June 2019

Analysis of trajectory such as detection of an outlying trajectory can produce inaccurate results due to the existence of noise, an outlying point-locations that can change statistical properties of the trajectory. Some trajectories with noise are repairable by noise filtering or by trajectory-simplification. We herein propose the application of a trajectory-simplification approach in both batch and streaming environments, followed by benchmarking of various outlier-detection algorithms for detection of outlying trajectories from among simplified trajectories. Experimental evaluation in a case study using real-world trajectories from a shipyard in South Korea shows the benefit of the new approach.
WC-1 and the Proximal GATA Sequence Mediate a Cis-/Trans-Acting Repressive Regulation of Light-Dependent Gene Transcription in the Dark
Authors: Brenna Andrea , Talora Claudio
Published: June 2019

Light influences a wide range of physiological processes from prokaryotes to mammals. Neurospora crassa represents an important model system used for studying this signal pathway. At molecular levels, the WHITE COLLAR Complex (WCC), a heterodimer formed by WC-1 (the blue light photo-sensor) and WC-2 (the transcriptional activator), is the critical positive regulator of light-dependent gene expression. GATN (N indicates any other nucleotide) repeats are consensus sequences within the promoters of light-dependent genes recognized by the WCC. The distal GATN is also known as C-box since it is involved in the circadian clock. However, we know very little about the role of the proximal GATN, and the molecular mechanism that controls the transcription of light-induced genes during the dark/light transition it is still unclear. Here we showed a first indication that mutagenesis of the proximal GATA sequence within the target promoter of the albino-3 gene or deletion of the WC-1 zinc finger domain led to a rise in expression of light-dependent genes already in the dark, effectively decoupling light stimuli and transcriptional activation. This is the first observation of cis-/trans-acting repressive machinery, which is not consistent with the light-dependent regulatory mechanism observed in the eukaryotic world so far.
Achieving Pain Control in Rheumatoid Arthritis with Baricitinib or Adalimumab Plus Methotrexate: Results from the RA-BEAM Trial
Authors: Taylor Peter C. , Lee Yvonne C. , Fleischmann Roy , Takeuchi Tsutomu , Perkins Elizabeth L. , Fautrel Bruno , Zhu Baojin , Quebe Amanda K. , Gaich Carol L. , Zhang Xiang , Dickson Christina L. , Schlichting Douglas E. , Patel Himanshu , Durand Frederick , Emery Paul
Published: June 2019

The purpose of the study was to assess the proportion of patients who achieve pain relief thresholds, the time needed to reach the thresholds, and the relationship between pain and inflammation among patients with rheumatoid arthritis (RA) and an inadequate response to methotrexate in RA-BEAM (NCT0170358). A randomized, double-blind trial was conducted, comparing baricitinib (N = 487), adalimumab (N = 330), and placebo (N = 488) plus methotrexate. Pain was evaluated by patient’s assessment on a 0–100 mm visual analog scale (VAS). The following were assessed through a 24-week placebo-controlled period: the proportion of patients who achieved ≥30%, ≥50%, and ≥70% pain relief, the time to achieve these pain relief thresholds, remaining pain (VAS ≤ 10 mm, ≤20 mm, or ≤40 mm), and the relationship between inflammation markers and pain relief. Baricitinib-treated patients were more likely (p < 0.05) to achieve ≥30%, ≥50%, and ≥70% pain relief than placebo- and adalimumab-treated patients, as early as Week 1 vs. placebo and at Week 4 vs. adalimumab. A greater proportion of baricitinib-treated patients achieved ≤20 mm or ≤40 mm remaining pain vs. placebo- and adalimumab-treated patients. Baricitinib-treated patients tended to demonstrate consistent pain relief independent of levels of inflammation control. In RA patients with an inadequate response to methotrexate, baricitinib provided greater and more rapid pain relief than adalimumab and placebo. Analyses suggest the relationship between inflammation and pain may be different for baricitinib and adalimumab treatments.
A Population Perspective on Prevention of Dementia
Authors: Eggink Esmé , Moll van Charante Eric P. , van Gool Willem A. , Richard Edo
Published: June 2019

The global number of people living with dementia is expected to increase to 130 million in 2050. Based on extensive evidence from observational studies, it is estimated that about 30% of dementia cases may be attributable to potentially modifiable risk factors. This suggests that interventions targeting these factors could perhaps delay or prevent the onset of dementia. Since the vast majority of people with dementia live in low- and middle-income countries, such interventions should preferably be easy and affordable to implement across a wide range of health care systems. However, to date, results from dementia prevention trials do not provide convincing evidence that treatment of these risk factors reduces the risk of dementia. The current paper aims to give an overview of available evidence for the potential for dementia prevention. In particular, we discuss methodological issues that might complicate the development of effective prevention interventions and explore the opportunities and challenges for future dementia prevention research. Currently, several ongoing and planned trials are testing the effect of multi-domain interventions on dementia risk in high-risk populations. It is desirable that future dementia strategies also target the wider population, through interventions on the individual, community, and population level, in order to constrain the growing prevalence of dementia worldwide.
Influence of the Adequacy of the Prenatal Care Utilization Index on Small-For-Gestational-Age Infants and Preterm Births in the United States
Authors: Shin Dayeon , Song Won O.
Published: June 2019

Little is known about the associations of Adequacy of Prenatal Care Utilization (APNCU) index with small-for-gestational-age (SGA) infants and preterm births. This study investigated the association between the Adequacy of Prenatal Care Utilization (APNCU) index in relation to small-for-gestational-age (SGA) infants and preterm births. We used data from 212,050 pregnant women from the Pregnancy Risk Assessment Monitoring System (PRAMS) between 2004 and 2011. Multivariable logistic regression analyses were performed to examine the effect of the APNCU index on SGA infants and preterm births after controlling for maternal sociodemographic factors. Women who received adequate-plus prenatal care in reference to adequate prenatal care had increased odds for delivering SGA infants (adjusted odds ratio (AOR) = 1.08, 95% confidence interval (CI) = 1.03–1.15). Women with 9–11 prenatal care visits had increased odds of delivering SGA infants (AOR = 1.07, 95% CI = 1.02–1.14) compared to those with more than 12 visits. Among the four APNCU index categories, the highest rate of preterm births was observed in the adequate-plus group. Compared to those with adequate prenatal care, women who received adequate-plus prenatal care had increased odds of preterm birth (AOR = 1.69, 95% CI = 1.55–1.84). Compared to those with more than 12 visits, women with fewer than eight prenatal care visits had increased odds of preterm birth (AOR = 1.29, 95% CI = 1.13–1.48). In conclusion, women in the adequate-plus APNCU index category were more likely to deliver SGA infants and to have preterm births compared to those in the adequate APNCU index category. Women in the U.S. with high-risk pregnancies were prone to receiving adequate-plus prenatal care. Future prospective studies are warranted to investigate the influence of APNCU index in relation to pregnancy and birth outcomes.
Effects of Exercise on Cognitive Performance in Children and Adolescents with ADHD: Potential Mechanisms and Evidence-based Recommendations
Authors: Christiansen Lasse , Beck Mikkel M. , Bilenberg Niels , Wienecke Jacob , Astrup Arne , Lundbye-Jensen Jesper
Published: June 2019

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with a complex symptomatology, and core symptoms as well as functional impairment often persist into adulthood. Recent investigations estimate the worldwide prevalence of ADHD in children and adolescents to be ~7%, which is a substantial increase compared to a decade ago. Conventional treatment most often includes pharmacotherapy with central nervous stimulants, but the number of non-responders and adverse effects call for treatment alternatives. Exercise has been suggested as a safe and low-cost adjunctive therapy for ADHD and is reported to be accompanied by positive effects on several aspects of cognitive functions in the general child population. Here we review existing evidence that exercise affects cognitive functions in children with and without ADHD and present likely neurophysiological mechanisms of action. We find well-described associations between physical activity and ADHD, as well as causal evidence in the form of small to moderate beneficial effects following acute aerobic exercise on executive functions in children with ADHD. Despite large heterogeneity, meta-analyses find small positive effects of exercise in population-based control (PBC) children, and our extracted effect sizes from long-term interventions suggest consistent positive effects in children and adolescents with ADHD. Paucity of studies probing the effect of different exercise parameters impedes finite conclusions in this regard. Large-scale clinical trials with appropriately timed exercise are needed. In summary, the existing preliminary evidence suggests that exercise can improve cognitive performance intimately linked to ADHD presentations in children with and without an ADHD diagnosis. Based on the findings from both PBC and ADHD children, we cautiously provide recommendations for parameters of exercise.
Bounded Perturbation Resilience and Superiorization of Proximal Scaled Gradient Algorithm with Multi-Parameters
Authors: Guo Yanni , Zhao Xiaozhi
Published: June 2019

In this paper, a multi-parameter proximal scaled gradient algorithm with outer perturbations is presented in real Hilbert space. The strong convergence of the generated sequence is proved. The bounded perturbation resilience and the superiorized version of the original algorithm are also discussed. The validity and the comparison with the use or not of superiorization of the proposed algorithms were illustrated by solving the l 1 − l 2 problem.