bluuebunny/crossref_metadata_2025 huggingface dataset:
Co-operative ideology
Authors: Adderley Ian
Published: January 2025

The material in this extract is drawn from Co-operatives: Linking practice and theory (Adderley, in press). The discussion focuses on the dual nature of co-operatives, which is both economic and social. An overview of the historical debate on co-operative ideology considers the different understandings of the dual nature. This is followed by a discussion of the cultural element before concluding with a discussion of who benefits from co-operatives.
Analisis Biaya Diferensial Pengambilan Keputusan Menerima Atau Menolak Pesanan Khusus (UMKM Naknik)
Authors: Wijaya Ade Ningsih , Rizqi Romadon  , Sarah Yuliana  , Berlian Aulia Harpa  , Efi Riyana  , Wiji Safitri
Published: January 2025

Manajemen perusahaan dalam pengelolaannya dihadapkan dengan berbagai jenis permasalahan sehingga perlu pengambilan keputusan yang efektif dan efisien agar memberikan keuntungan. Proses penentuan biaya dan manfaat tungga harus dibandingkan dengan alternatif lainnya. Biaya diferensial Mengacu pada biaya yang bervariasi di antara beberapa pilihan. Tujuan penelitian ini adalah menganalisis perbedaan biaya dalam formulasi keputusan penerimaan atau penolakan terhadap pesanan khusus pada UMKM Nasi Goreng Kembar Naknik. Metode penelitian yang digunakan dalam jenis penelitian ini adalah kualitatif dan bertujuan untuk menganalisis suatu masalah melalui studi deskriptif terhadap informasi berupa data yang ada. Penelitian menunjukkan bahwa penggunaan analisis biaya diferensial memberikan manfaat yang signifikan bagi UMKM (usaha mikro, kecil dan menengah) dalam hal pengambilan keputusan. Kami mengusulkan untuk menerima pesanan khusus Nasi Goreng Kembar Naknik UMKM karena hasil perhitungan menunjukkan keuntungan bersih sebesar Rp. 3,070,000 dari biaya yang dikeluarkan sebesar Rp. 9.530.000
Preface: 5th International Conference on Medical Imaging, Sanitation and Biological Pharmacy (MISBP 2024)
Authors: Mansfield Cornelius , Zou Gang
Published: January 2025

The 2024 5th International Conference on Medical Imaging, Sanitation and Biological Pharmacy (MISBP 2024) was successfully held during November 23-24, 2024 in Osaka, Japan. This conference aims to provide a platform for researchers and engineers to share their ideas, recent developments, and successful practices in medical imaging, sanitation, biomedical engineering, biochemistry, pharmacy, and human health.
The conference had 4 technical session and 4 poster sessions. Each keynote speech lasted 30-40 minutes, and authors presentation 8-10 minutes. Each presentation was included with questions and answers. MISBP 2024 became an effective communication platform for all the participants over the world. The conference proceeding is a compilation of the accepted papers and represent an interesting outcome of the conference.
We would like to acknowledge all of those who supported MISBP 2024. Especially we would like to thank the committee members and reviewers for their tremendous contribution in conference organization and peer review of the papers. We are sure that the proceedings will serve as an important research source of references and the knowledge, which will lead to not only scientific and engineering progress but also other new products and processes.
MISBP Conference Organizing Chair
Osaka, Japan
Application Value of Different Detection Methods in Diagnosis and Prognosis of Multiple Myeloma
Authors: Zhou Ziyang
Published: January 2025

Multiple myeloma (MM), being a hematological tumor with a high incidence, has seriously threatened people's health and drawn the attention of numerous research. In recent years, along with the continuous advancement of research, an increasing number of technologies have been utilized in the diagnosis and prognosis evaluation of MM, and the approaches for the diagnosis and prognosis assessment of MM have become increasingly diversified. Cytogenetic detection, molecular biology detection, hematological detection and imaging detection are widely used in the diagnosis and prognosis evaluation of MM. In addition, researchers are also using immunological detection, detection of circulating tumor cells and DNA, machine learning and other methods to actively search for new biological targets, and try the combined application of multiple diagnostic pathways to continuously optimize the diagnosis and prognosis evaluation of MM. This paper reviewed several methods for the diagnosis and prognostic evaluation of MM, analyzed some advantages and disadvantages of each method in the diagnosis and prognostic evaluation, and put forward some thoughts for future research directions.
The Diagnosis and Treatment Status of Common Diseases in Pet Dogs
Authors: Zhang Ruihan
Published: January 2025

With the improvement of people's living standards, more and more people need the companionship of pets, and pet dogs are the largest proportion of all kinds of pets, and the number of people entering the human family is also constantly surging, becoming a member of the human family. However, pet dogs are not always healthy, and a variety of common diseases endangering the health of pets will also break out in pet dogs, which requires strengthening the prevention and treatment of common diseases of pet dogs, reducing the pain caused by pet diseases, reducing the mental pain of pet owners, and reducing the economic burden of families. Breeding personnel must deeply understand the importance of pet dog epidemic prevention and control, in addition to seriously do a good job in the daily breeding of feeding, cleaning, disinfection, but also should pay close attention to the external performance of the dog, in order to strictly grasp the prevention and control of pet dog epidemic.
A Review of The Use of Silk Fibroin in Sports Medicine/Injury
Authors: Fu Yue
Published: January 2025

Due to the increased promotion of sports and life span in many countries, sports medicine has become an important area for further research and investigation. With the advancement of technologies, tissue engineering is a prevalent topic for future development. Silk has been used for therapeutic strategies in many different areas since the Neolithic Age. Silk fibroin is a protein extracted from silk with a special structure with many potentials. This article will focus on the use of silk fibroin in common Musculoskeletal injuries which is divided into three areas: open wound injuries, fracture, and tissue engineering. However, traditional therapies for these three areas present limitations such as graft rejection and requiring a second surgery. Hence the article aims to explore the application of silk and how silk overcomes these limitations in medical applications when combined with other materials. SF demonstrates many potentials in medical applications based on the properties of excellent biocompatibility, causing a mild immune response, and supporting cell proliferation and tissue regeneration.
The Toxicity Mechanism and Treatment Methods of Poisonous Mushrooms
Authors: Zhu Leer
Published: January 2025

Poisonous mushrooms act as decomposers in the ecosystem. Because of their confusing resemblance to common mushrooms, they are often eaten inadvertently and cause serious poisoning. Different poisonous mushrooms contain different kinds of toxins, such as goitrogens and umbrella toxins. Poisoning can cause irreversible damage to organs such as the liver and kidneys. Clinical symptoms and duration of poisoning vary among different types of poisonous mushrooms in different regions. The most common clinical manifestations include gastrointestinal symptoms, liver failure and neurological disorders. Current diagnostic tools are mainly based on symptomatology and laboratory tests such as high-performance liquid chromatography. Treatment after poisoning is generally supportive therapy and antidotes, and in extreme cases liver transplantation is considered. In this research, two of the most typical poisonous mushrooms, the gooseberry and the death cap, were used as examples by analyzing open source information and cases. Their toxin composition poisoning symptoms as well as the principles of toxicogenesis were studied. Treatment strategies for poisonous mushroom poisoning are proposed, which can provide scientific basis for future prevention and treatment.
Preparation of Black Phosphorus and the Application in Biomedicine
Authors: Qian Kawai
Published: January 2025

This work presents an in-depth exploration of black phosphorus (BP) nanosheets, highlighting their transformative potential in advancing cancer treatment. As cancer continues to be a leading cause of death worldwide, current therapies often fall short of delivering targeted and effective treatment with minimal side effects. In response to this need, BP nanosheets are considered to be a kind of promising multifunctional materials for cancer therapy. The work begins with an overview of the pressing challenges and the limitations of current targeted therapies, including issues like drug resistance and systemic toxicity. It then delves into the various methods of BP nanosheet preparation, including top-down and bottom-up approaches, which are critical in enhancing their properties for biomedical applications. Furthermore, the diverse applications of BP nanosheets are thoroughly examined, particularly their roles in photothermal therapy, photodynamic therapy, and drug delivery. BP nanosheets also offer the capability to regulate the tumour microenvironment and enable combined treatment modalities. Their multifunctionality and potential to integrate multiple therapeutic approaches provide a compelling solution to overcome the drawbacks of existing cancer treatments, thus paving the way for safer and more effective therapies.
Nipah Virus: An Overview of What Have Known and Learnt
Authors: Ruan Yejin
Published: January 2025

Nipah virus (NiV) is a zoonotic Biological Safety Level 4 (BSL-4) pathogen with a high fatality rate and high risk of transmission, which came into public view during the end of the last century. NiV in human usually results in a series of severe symptoms, from critical respiratory illnesses and acute encephalitis. Pteropus bat species distributed broadly across Asia, Africa and Oceania are the natural hosts of the NiV. Most viral outbreaks are reserved to countries of South and South-East Asia, especially Bangladesh. Molecular examination methods such as RT-PCR and ELISA are effective for the diagnosis of the disease, though some steps should be simplified and revised in order for the assays to become more viable in underdeveloped countries. Currently no cure has been developed for this infectious disease. Diagnosed patients should be given adequate supportive care for better recovery and improved prevention procedures should be acquired in order to prevent further spread of the virus.
Current Advances and Future Outlook of Cancer Immunotherapy
Authors: Du Yuhang
Published: January 2025

In the following discourse, I will delve into the array of immunotherapeutic approaches. Presently, immunotherapy stands at the forefront of cancer treatments within medical facilities, representing a significant shift in the way to approach the management and eradication of malignant diseases. It encompasses the employment of ICI (Immune checkpoint inhibitors), CAR-T cells (Chimeric Antigen Receptors), and cancer vaccines. Each of these methods represents a different facet of the immune system's potential to combat cancer, and each has its unique mechanism of action and clinical application. To begin with, ICI (Immune checkpoint inhibitors) are a groundbreaking class of drugs that have revolutionized cancer treatment. These inhibitors work by targeting specific proteins on immune cells and cancer cells that act as checkpoints, effectively turning off immune responses. By blocking these checkpoints, CAR-T cell therapy, on the other hand, is a form of immunotherapy that involves genetically modifying a patient's own T cells to recognize and destroy cancer cells. This is achieved by introducing a gene for a chimeric antigen receptor into the T cells, which enables them to target specific antigens on the surface of cancer cells. Cancer vaccines are another promising avenue in immunotherapy. Unlike traditional vaccines that prevent infectious diseases, cancer vaccines are designed to treat existing cancer or prevent its recurrence.
The Structure, Property, Preparation and Application of Carbon Nanotube in Biosensors
Authors: Wang Jingdong
Published: January 2025

Instruments known as biosensors are highly sensitive to biological materials and have the ability to detect concentrations by converting them into electrical signals. High-sensitivity detection of complex biological samples can be achieved by utilizing the specificity and sensitivity of biomolecules. Due to the high sensitivity, high selectivity and important applications of biosensors, they have attracted much attention. It is reported that the materials used in biosensors have a significant impact on their detection sensitivity. Therefore, exploring new functional materials to modify biosensors is helpful to improve the sensitivity and the accuracy of the biosensors. Carbon nanotubes, exhibit good stability of structure and excellent performance, such as mechanical properties, thermal conductivity and optical properties. As a result, in recent years, research on using carbon nanotubes for biosensor modification has gained a lot of attention. The characteristics and categorization of carbon nanotubes are described in this article. The process required for prepare carbon nanotubes and different biosensors based on carbon nanotubes are also outlined. Additionally, the methods for creating carbon nanotubes and how they are used in biosensors are discussed.
Effects of Hormonal Changes During Puberty on Cognition and Mood
Authors: Li Yige
Published: January 2025

This article explores the hormone surge during puberty and its wide-ranging effects on adolescent behavior, mood, and cognition, highlighting the importance of this area for future research. The onset of puberty leads to increased secretion of sex hormones such as estrogen and testosterone, which bring physical, emotional, and behavioral changes by activating the hypothalamic-pituitary-gonadal axis. This article provides insights into how these hormones affect adolescent brain development, particularly areas such as the prefrontal cortex and hippocampus that are responsible for higher-order thinking and memory. Hormone fluctuations not only affect adolescents' attention and processing abilities, but also lead to mood swings, increased stress sensitivity, and sex differences in externalizing behaviors (such as aggression) and emotion regulation. Girls are more prone to mood swings due to cyclical fluctuations in estrogen and progesterone, while boys exhibit risk-taking behaviors associated with testosterone. In addition, sex hormones affect adolescents' social cognition, self-esteem, and body image, leading to increased insecurity and social sensitivity. This article calls for providing adolescents with healthy coping strategies and supportive environments, and, if necessary, therapeutic interventions to help them through the challenges of this period, and points to directions for future research.
Design of a New Whole Merozoite Vaccine for Malaria
Authors: Cai Mingwei , Wu Suyu , Zhang Yuwei
Published: January 2025

Malaria is one of the most fatal diseases in the sub-Saharan area, causing more than 200 million people infected and more than 600000 people dead every year. The whole society are working together to develop vaccine to prevent people from being infected. This research will focus on a new whole merozoites vaccine which contains CRISPR-Cas9 based CyRPA protein deficient merozoites. The vaccine is designed to prevent the merozoites from entering the red blood cells so it can stay in the blood, be exposed the immune system and stimulate immune response. This new vaccine can provide a durable and effective prophylactic effect if successful. The vaccine is expected to have no serious and fatal side effects and will undergo animal tests and voluntary tests to test its effectiveness. Further research will focus on resolve the remaining challenges of the vaccine, including red blood cell deformation and the possibility of merozoites still entering the blood cells.
Progress of Research on Rehabilitation Treatments for Specific Symptoms of Knee Osteoarthritis
Authors: Han Xu
Published: January 2025

Knee osteoarthritis (KOA) is a common chronic degenerative bone and joint disease characterized by knee degeneration, pain, stiffness and knee dysfunction. The global prevalence of KOA has been gradually increasing with the aging of society and changes in lifestyle, rising by nearly 50% in the last 30 years, causing a heavy health and economic burden to patients, families and society. KOA cannot be completely cured at present, and all relevant guidelines recommend non-surgical and non-pharmacological treatments, mainly rehabilitation, as the preferred basic treatment for KOA. This paper adopts the literature search method to systematically analyse the relevant literature in the past 5 years, and review the rehabilitation methods for treating specific symptoms caused by KOA and the existing benefits and limitations of each therapy from various aspects, such as physiotherapy, occupational therapy, traditional Chinese medicine rehabilitation and emerging therapies, with a view to providing more valuable reference information for clinical rehabilitation and researchers, and to promote further development and application of rehabilitation methods for KOA.
Metal-Organic Frameworks: Performance, Fabrication, and Applications in Biosensors
Authors: Wu You
Published: January 2025

Biosensors serve as key detection tools in many fields, such as clinical diagnosis, environmental monitoring and food safety. Although breakthroughs have been achieved in the field of sensor technology, related issues such as sensitivity, specificity and stability remain unresolved. Recent academic research has highlighted the significant prospects of metal-organic frameworks (MOFs) as potential solutions to these problems. The MOFs, which are composed of organic ligands and metal ions, have high surface area, adjustable pore size and excellent chemical versatility. By optimizing these characteristics, the sensitivity and selectivity of biosensors are improved, thereby improving their performance. This study analyzes the extensive research on MOF-based biosensors. This paper emphasizes their synthesis methods, functionalization strategies, and applications. Specifically, the application here is mainly in the detection of biomarkers of cancer and cardiovascular diseases. The role of MOFs-based biosensors in cell and tissue imaging is discussed as well. The goal of this research paper is to explain the latest research results and define potential areas of exploration for subsequent scientific research works. This work would contribute to improve MOF-based biosensing technology.
Current Research on the Diagnosis Method of Meniscus Root Injury and its Healing
Authors: He Yun , Wang Jiahao , Yang Zongheng
Published: January 2025

Currently, meniscus injury has become a common disease among sports and fitness enthusiasts in China, with root meniscus injury accounting for a larger proportion, which damage impairs load distribution throughout the knee joint, reducing the surface area to bear the load and making patients susceptible to early degenerative changes that alter their daily activities. This injury has been ignored for a long time, and in recent years people have begun to pay more attention to it. However, the diagnosis of root meniscus injury is difficult to detect, and the current mainstream method is MRI examination, combined with X-ray and arthroscope examination. However, with people's increasing emphasis on health, some may not accept surgical treatments such as meniscus repair or meniscectomy. Therefore, non-surgical treatments such as drug injection are gradually being used. In this paper, the literature on meniscus root injury in recent years was reviewed, and the anatomy, injury mechanism and intervention of meniscus root were reviewed, so as to further understand the current progress of injury.
The Mechanism and Treatment Strategy of Neurogenic Muscle Atrophy
Authors: Lin Haoyan
Published: January 2025

After peripheral nerve injury (PNI), axial buds emerge from the proximal end of the injured area, providing nerve supply to the skin and muscles of the injured area. Lower nerve regeneration, however, may result from sluggish axonal renewal. As a result, it could take a while for the skin and muscles in the wounded area to regain innervation from the proximal nerves. PNI generally does not threaten the patient's life, but it may cause atrophy in muscles that have lost nerve control. Long term denervation can lead to corresponding skeletal muscle atrophy. Currently, many studies are gradually focusing on neurogenic muscle atrophy, but its mechanism of occurrence is still far from fully understood, and the treatment methods are also relatively limited. At present, surgical treatment and electrical stimulation therapy are mainly used in clinical practice to prevent and treat neurogenic muscle atrophy. In recent years, with the development of technologies such as cell biology, molecular biochemistry, immunohistochemistry, and electrophysiology, people have delved deeper into the mechanisms of neurogenic muscle atrophy, and the underlying mechanisms have been continuously understood and discovered. New treatment methods have also emerged.
Application of nanomaterials for the treatment of glioblastoma
Authors: Hu Yufei
Published: January 2025

Glioblastoma, as the most severe type of primary brain tumor, presents great difficulties in treatment due to its fast-growing nature, recurrence, and resistance to typical treatment methods. A particularly hard challenge is the blood-brain barrier (BBB), which makes it difficult for many drugs to reach tumor regions in enough amounts for the treatment to work well. Nanomaterials may provide one possibility for enhancing immunotherapy in glioblastoma by improving the delivery of drugs, helping them cross the BBB, and adjusting immune responses. This research looks at recent progress in using nanomaterials for glioblastoma treatment, focusing on types of organic and inorganic nanoparticles. Organic nanomaterials like lipid-based or polymer nanoparticles have the potential to deliver drugs directly to the tumor, with longer-lasting effects. Inorganic nanomaterials, such as magnetic nanoparticles, iron oxide ones, or gold nanoparticles, have been shown to be helpful for hyperthermia and photothermal therapy, as well as improving radiotherapy. These nanomaterials can be used alone or as vaccine adjuvants, providing practical options for getting through the BBB and delivering therapeutic agents to the tumor site. The integration of nanomaterials into glioblastoma treatments holds a certain potential to create better treatment plans for glioblastoma cases.
Differential Analysis and Application Prospects of DNA Tumor Biomarkers in The Five Major Types of Tumors
Authors: Jiang Yunzhen , Wang Ruofan
Published: January 2025

With the increasing global burden of cancer, the study of tumor biomarkers (TMs) is of great significance as key tools for early diagnosis, disease monitoring, treatment efficacy evaluation, and prognosis judgment of cancer. This study focuses on the five major tumor types: lung cancer, colorectal cancer, liver cancer, female breast cancer, and gastric cancer. By screening and integrating relevant data on the clinVar website, this article classified, quantified, and analyzed the differences in DNA TMs identified in the five major tumor types mentioned above. In addition, this article explores the mechanisms and principles of DNA tumor biomarker types with relative commonality and specificity in tumor formation and spread among the five major tumor types. We found that the mechanism characteristics of common TMs in the five major tumor types are relatively concentrated; The mechanism characteristics of TMs unique to the five major tumor types are more dispersed. The frequency of occurrence of DNA tumor biomarker mechanism classification has a certain directional effect on tumor types and has a positive impact on the judgment of tumor types. This study aims to provide theoretical support for the discovery, refinement, and personalized clinical application of more TMs in the future, and to improve the survival rate and quality of life of cancer patients.
Molecular Glues and Molecular Glue Degraders: Mechanisms, Design, and Therapeutic Applications
Authors: Shi Haonan
Published: January 2025

Molecular glues and molecular glue degraders appear to be a fast-growing class of therapeutic agents that selectively modulate protein-protein potential interactions and can enhance the selective degradation of proteins. These small molecules are providing the possibility to target proteins that previously thought to be very challenging or inaccessible that are involved in a host of diseases. The present review focuses on describing the basic concepts of molecular glues and the rationale behind the interactions and the general concept that drives their design. Special attention is paid to their uses in cancer therapy, neurodegenerative diseases, and infections therapy. Exploring new therapeutic targets and drugs based on the molecular glue degraders’ ability to recognize and bind E3 ubiquitin ligases and promote ubiquitination proteolysis of specific proteins. Furthermore, the review looks at some of the limitations and the difficulties in the creation of these agents, as well as that potential in the field of pharmacogenomics. Thus, future expansion of molecular glue with state-of-the-art technologies including artificial intelligence and CRISPR is expected to extend its therapeutic applicability; evidently a step-up for targeted therapies. In this review, it offers the state-of-art on molecular glue studies and future direction for such work.
TNF-α, NF-kb and NLRP3 in Relation to Tumor Development
Authors: Li Shujian
Published: January 2025

With the development of society, cancer has become one of the major diseases with a high incidence and fatality rate in the world.Scientists have proved that TNF-α,NF-kb and NLRP3 plays an important role in the tumor microenvironment (TME), especially their dual effects in regulating inflammation and tumor progression. However, there is still a lack of a comprehensive understanding of the specific mechanisms of these molecules in different tumor types and their interactions, which also limits their potential application in tumor immunotherapy. Therefore, the study of the relationship between inflammatory factors and tumor development has become a hot topic in today's society. For example, the inflammatory factor TNF-α secreted by NF cells and T cells can directly annihilating tumor cells, and can indirectly kill tumor cells by activating the immune system’s response, NF-kb and NLRP3 also inhibit tumor growth, invasion and metastasis under specific conditions. In conclusion, inflammatory cytokines are closely related to the development of tumors, and this study also provides a solid foundation for future immunotherapy of tumors. This article focuses on the promotion and inhibition effects of inflammatory factors TNF-α, NF-kb and inflammatory body NLRP3 on tumors, providing evidence and conclusions for researchers.
Pengaruh Struktur Modal, Likuiditas, dan Pertumbuhan Penjualan terhadap Nilai Perusahaan dengan Profitabilitas sebagai Variabel Mediasi Studi pada Perusahaan yang Terdaftar di BEI Periode 2019 – 2024
Authors: Anggraini Diana Indah Sri Lestari Pratiwi , Hwihanus Hwihanus
Published: January 2025

The food and beverage industry listed on the Indonesia Stock Exchange (IDX) between 2019 and 2024 is the subject of this study, which empirically investigates the link between capital structure, liquidity, sales growth, and business value. Using structural equation modeling (SEM) through SmartPLS 4, this study finds empirical evidence that capital structure significantly influences firm liquidity. However, it was discovered that company value was not significantly impacted by capital structure, liquidity, sales growth, or profitability. These results imply that company value in the food and beverage industry may be more heavily influenced by variables beyond the purview of this investigation.
KOLABORASI MAHASISWA DAN PT PROXI DALAM PENGEMBANGAN KEAHLIAN KEAMANAN JARINGAN UNTUK MENDUKUNG TRANSFORMASI DIGITAL YANG AMAN
Authors: Tirawati Tirawati , Insany Gina Purnama
Published: January 2025

This community service activity aims to improve students competence in network security strategies through collaboration with PT Proxi, an internet service provider company. This training focuses on the use of MikroTik devices and Winbox applications for firewall configuration as an effort to improve network security. Simulations are carried out using a simple topology between MikroTik and laptop devices to implement network filtering with certain rules. The results of this activity show that the firewall configuration is able to block access to unwanted sites or IP addresses, increasing protection against cyber threats. Thus, this activity is expected to not only increase student capacity but also provide benefits to the community in supporting a safer and more sustainable digital transformation.
APPLICATION OF THE SINTAP ANALYSIS IN THE CASE OF A THICKWALLED PRESSURE VESSEL WITH CRACKS IN THE SUPPORT ZONE
Authors: Vukojević Nedeljko , Bajtarević Jeleč Amna , Mizdrak Vedran
Published: January 2025

Fracture mechanics is a field that is increasingly studied and applied in modern industry. One of the most widely accepted methods for assessing structural integrity in this field is the SINTAP method. Although there are many literary sources available that discuss this
method, very few of them present its concrete application. This paper presents the application of the mentioned method, along with appropriate equations, at a basic level of analysis. The relevant fracture mechanics parameters are determined numerically using
Ansys software, with the example of a thick-walled pressure vessel with cracks in the support zone. The analysis takes into account the effects of operational loads, as well as residual stresses resulting from welding.
PERMANENT COURT EXPERT WITNESSES IN THE FIELD OF MECHANICAL ENGINEERING IN THE LEGAL SYSTEM OF BOSNIA AND HERZEGOVINA
Authors: Šehović Nermin
Published: January 2025

The paper aims to explain the concepts related to proving and to permanent court expert witnesses, as a means of proving in the legal system of Bosnia and Herzegovina, on the basis of the legal and legislative framework that is a prerequisite for the performance of expert witnesses work in Bosnia and Herzegovina. The paper starts with: the conditions
and procedures for appointing experts and professional commissions needed for the process of appointing experts, lists of expert witnesses and directory of expert witnesses, supervision of their work done by the authority leading the procedure, periodic assessment of expert witnesses' work, measures of public reprimand and dismissal of experts, rights and duties of experts, tariff on awards and reimbursements of expenses for the work of expert witnesses and staff list, and institutional capacities of permanent court expert witnesses in the field of mechanical profession in Bosnia and Herzegovina..
APPLICATION OF THE PLANNED EXPERIMENT FOR DETERMINING THE STRESS INTENSITY FACTOR IN VESSEL HEADS USING FEM ANALYSIS
Authors: Vukojević Nedeljko , Šabanović Kenan , Barlov Adnan
Published: January 2025

This paper deals with the numerical determination of the stress intensity factor KI for meridional cracks on the ellipsoidal head of pressure vessels. The experiment was carried out according to selected parameters, including vessel diameter, wall thickness and pressure. The analysis of the results concluded that the cylindrical segment of the ellipsoidal head and the crown of the ellipsoidal head are the most critical places for the appearance of cracks, exposed to tensile stresses. Regression analysis determined that the internal pressure has the greatest influence on the KI factor, while the diameter of the vessel is also significant for the crown of the ellipsoidal head. The conducted experiments confirm the obtained regression models, although deviations attributed to the imperfections of the numerical simulations were observed. Despite this, it is concluded that the obtained values of the KI factor are satisfactorily accurate.
Wearable sensor-based real time monitoring system for physical education teaching and training
Authors: Tian Tuo
Published: January 2025

The comprehensive progress of mental and physical quality is majorly influenced by the college physical education, which is considered a part of the educational system. Developing a scientific and efficient evaluation index is significant to compute physical education teaching quality. The traditional methods of assessing performance in physical education often rely on subjective evaluations or delayed feedback from manual data collection. To overcome these challenges, a design based on a real-time monitoring system is introduced that leverages wearable biosensor technology to improve physical education teaching and training. Initially, some physiological indicators, namely heart rate, respiration rate, body temperature, and motion activity, were recorded and analysed to provide individualized insights into physical performance. Data pre-processing is performed using a median filter to reduce noise and Z-score normalization to standardize the input dataset. Key features are extracted using Fast Fourier Transform (FFT), enabling the identification of critical performance metrics. A Rat Swarm Optimized Efficient Random Forest (RSO-ERF) algorithm was introduced to enhance classification accuracy and optimize system performance. Experimental results demonstrate the proposed system’s effectiveness in providing real-time feedback, identifying individual fitness levels, and supporting adaptive teaching strategies. The increased system’s analysis tendency allows for customized training regimens, ongoing feedback, and improved physical health metrics monitoring. It also gives educators the ability to make data-driven decisions, encourage safety, and improve the educational experience for athletes and students. The findings underscore the potential of wearable biosensor technology combined with advanced algorithms in transforming physical education methodologies for improved engagement and performance outcomes.
The application of artificial intelligence in biomechanical feedback and learning effectiveness enhancement in ideological and political education
Authors: Guo Yingzhe
Published: January 2025

The application of artificial intelligence (AI) in ideological and political education (IPE) optimizes the learning effect with the help of biomechanical feedback mechanism, and provides technical support for deepening the reform of IPE in colleges and universities. With the help of AI technology, especially its advantages in data analysis and deep learning (DL), accurate matching and personalized recommendation of learning resources can be realized. In this study, an AI-assisted IPE system with biomechanical feedback was constructed. By analyzing students’ physiological reactions and behavior patterns in the learning process, the system can evaluate the learning state and adjust teaching strategies. The key findings show that this learning method combined with biomechanical feedback can significantly improve students’ learning participation, understanding depth and satisfaction, and make IPE more in line with students’ needs.
Student physical education teaching achievement test incorporating biomechanics analysis via decision tree algorithm
Authors: Zhao Ningning , Wang Lei , Sun Hongxia
Published: January 2025

In the context of China’s economic growth, building a “sports power” is crucial. With the Internet’s development, the nation focuses on physical education curriculum and students’ test results. Currently, Chinese students’ physical education achievements are mainly evaluated by storage, inquiry, and basic statistics. Digital mining is under - utilized, leaving much data unexplored. But digital education’s progress has brought educational data to the fore, enabling schools to find value and patterns for better teaching decisions. In this case, this paper delves into the integration of biomechanics analysis into the assessment of student physical education teaching achievements. Biomechanics offers invaluable insights into the mechanical aspects of human movement during physical activities. By examining biomechanical factors such as joint angles, muscle forces, and movement velocities during various sports, a more profound understanding of students’ physical capabilities and performance can be achieved. Taking the physical test results of students in a specific school as a case study, this research employs data mining technology to explore the rich dataset. The optimized decision tree algorithm is then utilized to analyze the biomechanics - related data. This algorithm enables the identification of key factors that influence students’ physical test outcomes. For instance, it can pinpoint how a student’s running gait mechanics, including stride length, frequency, and leg - muscle activation patterns, affect their performance in track - and - field events. Through this comprehensive approach, the paper not only aims to uncover hidden information within the physical test data but also to elucidate the intricate interplay between biomechanics and students’ overall physical education performance. By dissecting the factors that influence physical test results from a biomechanical perspective, this study provides actionable insights for enhancing physical education teaching methods. Educators can leverage these findings to design personalized teaching programs that cater to the unique biomechanical characteristics of each student, thereby optimizing the effectiveness of physical education and promoting students’ physical development and athletic performance.
Đặc điểm lâm sàng, hình ảnh nội soi của bệnh nhân loét dạ dày, tá tràng có nhiễm vi khuẩn Helicobacter Pylori tại Bệnh viện Đại học Y Thái Bình
Authors:   Trường Đại học Y Dược Thái Bình, Như Quỳnh Trần
Published: January 2025

Mục tiêu: Mô tả đặc điểm lâm sàng, hình ảnh nội soi của bệnh nhân loét dạ dày, tá tràng có nhiễm vi khuẩn Helicobacter pylori tại Bệnh viện Đại học Y Thái Bình.
Phương pháp: Nghiên cứu mô tả thực hiện ở 80 người từ 18 tuổi trở lên được chẩn đoán loét dạ dày và/hoặc loét tá tràng có vi khuẩn Helicobacter pylori (+).
Kết quả: Triệu chứng lâm sàng của bệnh nhân chủ yếu là đau hoặc nóng rát thượng vị (66,2%), tiếp theo là ợ hơi, ợ chua (46%), đầy bụng, khó tiêu (53,7%) và triệu chứng ít nhất là xuất huyết tiêu hóa và thiếu máu đều chiếm (13,8%).
Vị trí ổ loét trên nội soi chủ yếu gặp là loét hành tá tràng (58,8%), vị trí ở loét ở dạ dày (33,7%) và loét kết hợp (dạ dày và hành tá tràng) chiếm 7,5%. Số lượng ổ loét chủ yếu là 1 ổ (71,3%). Các ổ loét có kích thước trung bình là 9,8 ± 4,7 mm; chủ yếu có kích thước dưới 10mm (55%), từ 10-20 mm (40%) và trên 20mm (5%).
Các tổn thương kết hợp loét dạ dày - hành tá tràng chủ yếu là viêm dạ dày (52,5%), tiếp theo là viêm trào ngược dạ dày thực quản (GERD) (16,2%) và thấp nhất là polyp dạ dày, hành tá tràng (2,5%).
Kết luận: Nội soi thực quản - dạ dày - tá tràng rất có giá trị trong chẩn đoán các bệnh lý dạ dày – tá tràng đặc biệt loét dạ dày – tá tràng.
Preserving Cultural Heritage: A Study of Abdygali Sariyev's Poetic Vision
Authors: Almas Oralbek , P.T. Auyesbayeva , Mambetov Zholdasbek , Daribaev Samal , Karbozov Yerkhan
Published: January 2025

Abdygali Sariyev, a prominent Kazakh poet and writer, stands as one of the most influential literary figures in Kazakhstan's 20th century. His work is characterized by deep philosophical reflection, a strong connection to Kazakh history and tradition, and a profound exploration of themes such as national identity, freedom, and the relationship between the individual and society. This paper explores the literary legacy of Sariyev by analyzing his most notable works, examining the thematic concerns that pervade his poetry, and evaluating his role within the broader context of Kazakh literature and culture. The methods employed in this study include a qualitative literary analysis, close reading of Sariyev’s works, and historical context evaluation. The paper further explores how Sariyev’s style, language, and imagery reflect both the traditional Kazakh oral poetry and the modernist movements of his time. By situating Sariyev within the cultural and political landscape of Kazakhstan during the Soviet era, this paper sheds light on how his works contribute to the development of Kazakh literature, providing insights into national consciousness and the power of literature to shape collective memory. Through examining primary texts and secondary scholarly interpretations, the study also seeks to highlight the continuing relevance of Sariyev’s poetic vision in post-Soviet Kazakhstan. The research underscores the importance of preserving the literary legacy of poets like Sariyev to understand the rich cultural heritage of Kazakhstan.
The Key Elements About How to Improve English Language Educators’ Teaching Competence through Continuous Professional Development (CPD)
Authors: LI QIN , Mohammed Lubna Ali
Published: January 2025

This study aims to assess the impact of Continuing Professional Development (CPD) training on the teaching competence of English language educators at application-oriented universities in Henan, China. By employing a systematic literature review and bibliometric analysis, the study gathers and evaluates relevant data to understand the current state of CPD in English language instruction within this specific geographical and educational context. The research analyzes previous trends and their effects, identifying key areas for future refinement and targeted development. The study provides significant insights and practical implications for enhancing English language teaching competence through CPD in Henan and within the broader educational landscape of China. The findings indicate that recent publications from 2022 to 2024 have a limited citation impact, suggesting a lack of studies specifically addressing CPD’s role in English language training. Addressing this gap will help in the development of customized CPD programs for application-oriented universities, aligning with China’s strategic goals to improve English proficiency and promote international business and technological capabilities. The study also highlights that CPD research often draws insights from psychology and medical training, implying that a multidisciplinary approach can enhance the effectiveness of CPD for English language instruction. The relatively declining citation impact of Chinese educational research compared to European studies underscores the need for Chinese institutions to strengthen global collaborations and publish important findings in accessible journals to increase the global visibility and influence of their CPD advancements.
Impact of Green Marketing And Total Quality Management (TQM) Dimensions on Improving the Financial Performance of Indonesian Sharia Banks: New Concept
Authors: Pranata Sudadi , Narimawati Umi , Syafei M. Yani
Published: January 2025

Green marketing is an advertising technique that focuses on promoting and selling products or services that have minimal or positive environmental effect. Given the growing awareness of environmental and sustainability concerns, this concept has gained increasing importance and attention in the fields of marketing and business management. Quality management is a strategy for continuously enhancing (continuous performance improvement) performance at all levels of an organization's operations and processes, as well as in all functional areas, by leveraging its people and financial resources. How to implement green marketing and total quality management to the financial performance of Bank Syariah Indonesia is the focus of this study. This study aims to investigate the effects of ecological marketing and total quality management on financial performance. This method of research employs multiple linear regression with a sample of 237 individuals, including financial administrators and employees. Consumer awareness has a positive effect on financial performance, consumer loyalty has a positive effect on financial performance, increased resource efficiency has a positive effect on financial performance, an obsession with quality has a positive effect on financial performance, teamwork has a positive effect on financial performance, and engagement and empowerment have a positive effect on financial performance, according to the findings of this study.
The Challenging Complication of Acquired Tracheoesophageal Fistulas: A Case Report
Authors: Lau Justin , Korakavi Gautam , Howard N. Scott
Published: January 2025

Rationale

Acquired tracheoesophageal fistulas (TEFs) are rare and challenging complications, particularly in critically ill patients, with high morbidity and mortality.

Patient Concerns

A 67-year-old woman presented with respiratory failure, persistent cuff leaks, and complications from nasogastric and feeding tube use.

Diagnoses

TEFs were identified via esophagoscopy and bronchoscopy, revealing dual mid-esophageal fistulas.

Interventions

Management included repositioning of the tracheostomy, surgical repair involving tracheal resection and esophageal repair with an omohyoid rotational flap, and extracorporeal membrane oxygenation support during surgery.

Outcomes

Despite initial postoperative improvement, the patient experienced complications, including an esophageal leak and bleeding, culminating in a transition to comfort care.

Conclusion

Prevention of acquired TEFs requires vigilant monitoring of device use and pressure. Surgical repair remains complex, with outcomes influenced by patient comorbidities and intraoperative challenges.
Scaling up integrated care for chronic diseases : exploring perspectives on agency, processes, mechanisms and structures
Authors:   , Martens Monika
Published: January 2025

This PhD started in 2019, embedded within the European-funded SCUBY project on facilitating scale-up of integrated care for chronic diseases in three contexts. It has now started to lead a life of its own, in this book, reflecting on agency, processes, mechanisms and structures required to scale-up. These four perspectives all support the aim of this thesis; to understand the scale-up of integrated care in diverse health systems. The role of policy dialogues, stakeholders, scale-up roadmap development and implementation and contextual processes pose central elements in this quest. Using case studies and qualitative research, we learn from scale-up efforts in a resource-constrained health system in a lower-middle-income country (Cambodia); a centrally steered health system in a high-income country (Slovenia); and a publicly-funded, highly privatised health care system in a high-income country (Belgium). We showcase and argue that both policy and (realist or theory-driven) implementation research are needed to study and close the gap between science and politics to scale-up. In summary, this thesis highlights the inherent complexity, ambiguity, uncertainty, and power dynamics involved in scaling up integrated care, emphasizing the need for collaborative, adaptive approaches that acknowledge diverse perspectives and meaningfully engage stakeholders in the problem-solving process.