bluuebunny/crossref_metadata_2025 huggingface dataset:
Heart Rate and Heart Rate Variability Changes Are Not Related to Future Cardiovascular Disease and Death in People With and Without Dysglycemia: A Downfall of Risk Markers? The Whitehall II Cohort Study
Authors: Hansen Christian S , Jørgensen Marit E , Malik Marek , Witte Daniel R , Brunner Eric J , Tabák Adam G. , Kivimäki Mika , Vistisen Dorte
Published: February 2021

Objective

Higher resting heart
rate (rHR) and lower heart rate variability (HRV) are associated with increased
risk of cardiovascular disease (CVD) and all-cause mortality in people with and
without diabetes It is unknown whether temporal changes in rHR and HRV may contribute
to this risk. We investigated associations between 5-year changes in rHR and
HRV and risk of future CVD and death, taking into account participants’
baseline glycemic state.

Research design and Methods

In this prospective population-based cohort study we investigated 4,611
CVD-free civil servants (mean age 60,
SD=5.9 years, 70% men). rHR and/or 6 indices of HRV were
measured. Associations of 5-year change in 5-minute rHR and HRV with fatal- and
non-fatal CVD and all-cause mortality or the composite of the two were assessed
with adjustments for relevant confounders. Effect modification by glycemic
state was tested.

Results

At baseline, 63% of
participants were normoglycemic, 29% had prediabetes and 8% had diabetes.
During a median (IQR) follow-up of 11.9 (11.4;12.3) years, 298 participants
(6.5%) experienced a CVD event and 279 (6.1%) died from non-CVD related causes.
We found no association between 5-year changes in rHR and HRV and future events.
Only baseline rHR was associated with all-cause mortality. A 10 beats per
minute higher baseline level showed a 11.4% higher rate of all-cause mortality
(95%CI:1.0;22.9%, P=0.032). Glycemic state did not modify associations.

Conclusion

Changes in rHR and HRV and possibly also
baseline values of these measures are not associated with future CVD or
mortality in people with or without dysglycemia.
Cell Cycle Regulation of the Pdx1 Transcription Factor in Developing Pancreas and Insulin-Producing β Cells
Authors: Admin Ada , Zhu Xiaogdong , Oguh Alexis , Gingerich Morgan A. , Soleimanpour Scott A. , Stoffers Doris A. , Gannon Maureen
Published: February 2021

Current evidence
indicates that proliferating β cells express lower levels of some functional
cell identity genes, suggesting that proliferating cells are not optimally
functional. Pdx1 is important for β-cell specification, function, and
proliferation and is mutated in monogenic forms of diabetes. However, its
regulation during the cell cycle is unknown.
Here we examined Pdx1 protein expression in immortalized β cells, maternal
mouse islets during pregnancy, and mouse embryonic pancreas. We demonstrate
that Pdx1 localization and protein levels are highly dynamic. In non-mitotic
cells, Pdx1 is not observed in constitutive heterochromatin, nucleoli, and most
areas containing repressive epigenetic marks.
At prophase, Pdx1 is enriched around the chromosomes prior
to Ki67 coating the chromosome surface. Pdx1
uniformly localized in the cytoplasm at prometaphase and became enriched around
the chromosomes again at the end of cell division, prior to nuclear envelope
formation. Cells in S phase have lower
Pdx1 levels than cells at earlier cell cycle stages, and over-expression of
Pdx1 in INS-1 cells prevents progression toward G2, suggesting that cell
cycle-dependent regulation of Pdx1 is required for completion of mitosis.
Together, we find that Pdx1 localization and protein level are tightly
regulated throughout the cell cycle. This dynamic regulation has implications
for the dichotomous role of Pdx1 in β-cell function and proliferation.
Deficits in the Skeletal Muscle Transcriptome and Mitochondrial Coupling in Progressive Diabetes-Induced CKD Relate to Functional Decline
Authors: Bittel Daniel C. , Bittel Adam J. , Varadhachary Arun S. , Pietka Terri , Sinacore David R.
Published: February 2021

Two-thirds of those with type-2 diabetes
(T2DM) have or will develop chronic kidney disease (CKD), characterized by
rapid renal decline that, together with superimposed T2DM-related metabolic
sequelae, synergistically promote early frailty and mobility-deficits that increases
risk of mortality. Distinguishing the mechanisms linking renal decline to
mobility deficits in CKD progression and/or increasing severity in T2DM is
instrumental in both identifying those at high-risk for functional decline, and
in formulating effective treatment strategies to prevent renal failure. While
evidence suggests that skeletal muscle energetics may relate to the development
of these comorbidities in advanced-CKD, this has never been assessed across the
spectrum of CKD progression, especially in T2DM-induced CKD. Here, using
next-gen sequencing, we first report significant downregulation in
transcriptional networks governing oxidative phosphorylation, coupled
electron-transport, electron-transport-chain(ETC)-complex assembly, and
mitochondrial organization in both middle- and late-stage CKD in T2DM.
Furthermore, muscle mitochondrial coupling is impaired as early as stage 3-CKD,
with additional deficits in ETC-respiration, enzymatic activity, and increased
redox-leak. Moreover, mitochondrial ETC function and coupling strongly related
to muscle performance, and physical function. Our results indicate that
T2DM-induced CKD progression impairs physical function, with implications for
altered metabolic transcriptional networks and mitochondrial functional
deficits, as primary mechanistic factors early in CKD-progression in T2DM.
Knowledge and Practice of Nurses on Healthcare Associated Infection
Authors: MM Alwadai
Published: February 2021

Background: Healthcare associated infections (HCAI) are among the major complications of modern medical therapy. While outbreaks often capture the attention of the media and the public, endemic HCAI represents the majority of infections encountered in healthcare and are associated with significant morbidity, mortality and healthcare costs. Objectives: The objectives of this study were to assess the nurses' level of knowledge on Healthcare Associated Infection, assess the nurses' practice on Healthcare Associated Infection and assess the association between nurses' level of knowledge and their practice on the Healthcare Associated Infection. Method: A cross sectional design study was carried out at King Fahad Hospital of the University in Kingdom of Saudi Arabia including all nurses working in medical, surgical, and emergency department units. Using a self-administered questionnaire for healthcare associated infection designed by (Yunfang Zhou, et al.), engaged the ANOVA test and pearson correlation analysis. Results: According to the results, knowledge and practice of nurses were found to be low; the overall score of HCAI knowledge was 40.20 ± 11.79 while the overall score of HCAI practice was 45.51 ± 11.04. Statistical significance differences were found for studied participants who undergone training programs on infection control their knowledge found to be high. In analyzing the categorical knowledge, it was noticed that nurses scored well in the knowledge of hand hygiene (80.5%) and healthcare workers safety (77%), and the lowest score was in HCAI pathogen identification (36.9%). On the other hand, analysis of categorical practice revealed that nurses were scored well in the HCAI pathogens (86%) and hand hygiene (70.6%), and the lowest score was obtained in sources of HCAI (38%). The Pearson correlation analysis demonstrated a positive relationship between the total knowledge and practice scores, i.e, r = 0.481, which is statistical significant (p <0.001).
Pressure Wounds and Skin Failure Secondary Scurvy. Prevention with Early Vitamin Micro Nutrient Supplements
Authors: MV Kaminski
Published: February 2021

Skin is the largest organ of the body. The dermis is primarily collagen. A collagen deficit results in skin failure with thinning to the point of transparency and disruption. (pressure wounds). The media of blood vessels is also primarily collagen. Here a deficit causes capillary fragility and purpura. A collagen fiber is a triple strand of protein. Plates initially produce three strands of procollagen which twist around each other, first to the left, then right and left again. The result is a fiber more flexible and stronger than a steel wire of the same diameter. Strength is due to cross linking between fibers at the frequent amino acid proline and lysine positions after hydrogenation by vitamin C. It was observed that patients referred for pressure wound care had scurvy at the time of consult. Diagnosing a collagen, i.e. Vitamin C deficit during the admission skin assessment is straight forward by bed side observation for dermal atrophy, purpura or skin tears. If an ample profile of all micro-nutrients with 1 gm of vitamin C was started along with biofilm control and adequate wound dressings, the existing pressure wounds promptly improved and new wounds were prevented.
Program Edukasi “TOLUNI” (Tanaman Obat Keluarga Usia Dini) di SDN 015 Kota Samarinda
Authors: Julianti Tri Budi , Ressandy Sylvan Septian
Published: February 2021

TOGA tanaman herbal yang memiliki khasiat sebagai obat yang banyak sekali memiliki manfaat bagi kehidupan, termasuk untuk mengatasi masalah kesehatan secara tradisional. Manfaat TOGA tidak hanya dirasakan oleh kalangan dewasa, tetapi dapat berguna bagi anak-anak. Dewasa ini, sebagian besar anak-anak tidak mengetahui jenis-jenis tanaman obat. Oleh karena itu, pengenalan akan TOGA pada usia dini sangat diperlukan untuk menumbuhkan kecintaan dan minat anak-anak akan tanaman obat yang berkhasiat bagi kesehatan. Dari Program Edukasi “TOLUNI” (Tanaman Obat Keluarga Usia Dini) ini menjadi salah satu wahana pembelajaran yang tepat untuk memperkenalkan berbagai macam mengenai TOGA kepada siswa/i sekolah dasar. Dari program edukasi TOLUNI inipula dapat mendorong sekolah-sekolah yang minim pekarangan agar tetap dapat memiliki banyak tanaman kaya khasiat, sehingga dapat dijadikan wahana pembelajaran bagi para siswa. Program Edukasi “TOLUNI” dilaksanakan di Sekolah Dasar Negeri 015 Kota Samarinda. Sosialisasi edukasi TOGA disampaikan kepada siswa kelas 5 dengan rentang usia 10 – 11 tahun dengan diberikan materi mengenai jenis-jenis TOGA, kemudian para siswa diajak untuk menghias wadah TOGA serta menanam TOGA yang diberi pupuk kompos. Para siswa diajarkan membuat produk tradisional rumahan yaitu jamu sederhana. Selanjutnya dilakukan pembinaan dan pengawasan setelah dilakukan sosialisasi. Dari 15 tanaman TOGA, diperoleh hasil 8 TOGA yang bertahan tumbuh dengan baik.
Upaya Penguatan Manajemen Pemasaran Hasil Perikanan Berbasis Media Online di TPI Sendangbiru, Kabupaten Malang, Indonesia
Authors: Aliviyanti Dian , Semedi Bambang , Yona Defri , Asadi Muhammad Arif , Kasitowati Rarasrum Dyah , Dewi Citra Satrya Utama , Lutfi Oktiyas Muzaky , Isdianto Andik
Published: February 2021

TPI Sendang Biru berada di Kabupaten Malang memiliki potensi yang besar baik dalam bidang penyediaan pasokan ikan ataupun sarana prasarana penunjang lainnya. Pelabuhan perikanan tersebut dipersiapkan sebagai pusat pertumbuhan ekonomi perikanan di wilayah selatan Provinsi Jawa Timur. Pemerintah melalui Direktorat Jenderal Perikanan Tangkap Kementerian Kelautan dan Perikanan Tahun 2018 telah menyelesaikan relokasi pembangunan kios ikan berkonsep higienis pada wilayah tersebut untuk menunjang mutu hasil ikan dan harga jual ikan tetap tinggi.  Sejalan dengan hal tersebut Pemerintah Propinsi Jawa Timur saat ini melakukan pengembangan jalur lintas selatan untuk mempermudah aksesbilitas. Namun, adanya wabah pandemi Covid-19 saat ini menyebabkan dampak yang besar pada berbagai bidang termasuk bidang perikanan. Hal tersebut menyebabkan bukan hanya minat beli masyrakat yang menurun, namun keterbatasan jalur distribusi produk juga menghambat transaksi jual-beli masyarakat. Berdasarkan hal tersebut perlu dilakukan pelatihan dan pembinaan manajemen pemasaran produk-produk perikanan di TPI Sendang Biru berbasis media jual-beli online. Metode edukasi yang dilakukan adalah seminar dengan topik strategi pemasaran digital berbasis media sosial dan workshop berbasis toko online atau marketplace. Melalui program ini diharapkan dapat menjadi salah satu langkah awal dalam menghadapi tantangan-tantangan baru dalam penanggulangan pemulihan ekonomi pasca pandemi Covid-19, serta dapat memperluas jejaring pemasaran para nelayan atau penjual ikan di wilayah tersebut bahkan hingga keadaan normal kembali.
SISTEM INFORMASI PERPUSTAKAAN SMP MUHAMMADIYAH 7 COLOMADU BERBASIS WEBSITE
Authors: Budiono Ihsan , Salsabilla Azzahra , Rachman Lail Nur , Putri Devi Afriyantari Puspa
Published: February 2021

Pada era globalisasi sekarang ini, segala sesuatu tidak luput dari peran teknologi. Penggunaan sistem informasi pun berkembang pesat, salah satunya sistem informasi perpustakaan sekolah berbasis website. Beberapa sekolah di Kabupaten Karanganyar belum memiliki sistem informasi ini. Salah satu contohnya SMP Muhammadiyah 7 Colomadu yang memiliki kendala bagian pengelolaan perpustakaan sekolah sehingga semua sistem peminjaman maupun pengembalian buku masih dilakukan secara manual. Tujuan website ini untuk mempermudah pengelolaan dan memperoleh data

buku perpustakaan beserta ISBN, peminjaman buku, pengembalian buku, dan denda yang harus dibayarkan. Dengan adanya website ini, pengelolaan buku akan menjadi lebih efektif karena data buku perpustakaan disimpan di dalam database sehingga mengurangi resiko kehilangan data buku pada perpustakaan sekolah.
REALTIME MONITORING ANTRIAN PENDAFTARAN PASIEN PUSKESMAS BERBASIS ANDROID DALAM UPAYA PENANGGULANGAN PENYEBARAN COVID-19
Authors: Gunawan Rohmat , Rahmatulloh Alam , Armiyati Laely , Aldya Aldy Putra
Published: February 2021

Antrian konvensional menjadi polemik yang umum di masyarakat. Lamanya proses pelayanan dan waktu tunggu antrian konvensional sangat mengganggu aktivitas sehari-hari. Di instansi kesehatan seperti puskesmas, rumah sakit dan poliklinik, bahkan proses antrian harus dilakukan oleh pasien sebagai pendaftar sebelum dapat dilayani. Untuk mengatasi masalah tersebut diusulkan sistem antrian digital berbasis mobile yang dapat diakses secara online. Pendaftar dapat melakukan registrasi melalui aplikasi eAntrian di smartphone yang terkoneksi dengan internet. Informasi nomor antrian akan diperoleh setelah pendaftaran dinyatakan valid. Selain itu, pendaftar juga mendapatkan informasi laju nomor antrian yang sedang dilayani secara real-time. Hasil dari kegiatan pengabdian ini antara lain: sosialisasi diikuti oleh 13 pegawai Puskesmas, demo aplikasi, uji coba aplikasi selesai dilakukan. Login sebagai pengguna dan pengelola pada aplikasi berhasil dilakukan. Ketika login sebagai pengelola, jenis layanan yang disediakan berhasil dibuat dan dapat ditambah sesuai kebutuhan. Monitoring proses antrian dibantu dengan tampilan jumlah pedaftar pada setiap layanan dan laju nomor antrian yang sedang dilayani. Sedangkan ketika login sebagai pengguna, nomor antrian berhasil diperoleh dan sistem berhasil menampilkan laju nomor antrian secara real-time.
Evaluation of renal functions tests among Sudanese healthy pregnant women attending antenatal care (ANC) at The National Ribat University Hospital in Khartoum State in 2019
Authors: Ali Ibrahim Abdelrhim , Hassan Elham Bourai , Elhassan Khalid S.
Published: February 2021

Pregnancy involves remarkable physiological changes and the functional impact of pregnancy on the kidney physiology is widespread involving practically all aspects of kidney functions. The aim of this study was to evaluate the renal functions in Sudanese healthy pregnant ladies during different trimesters. A cross sectional study was carried out during July to October 2019 on Sudanese healthy pregnant ladies attending antenatal care at the National Ribat University Hospital in Khartoum State. The study covered 60 healthy pregnant ladies (20 for each trimester). The purpose of the study was explained to all participants and they were assessed after taking their consent. Blood pressure (BP) and body mass index (BMI) were measured by standard techniques. A sample of five ml venous blood was taken in a suitable blood container for measurement of urea and creatinine using a fully automated Mindray BS-300 Chemistry Analyzer (Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, China). The data was analyzed using SPSS version 25 (IBM SPSS Inc.,Chicago, IL, USA), t-test was used to compare the statistical significant (p value ≤ 0.05 was considered statistical significant). The mean age of participants was 26.6±5.3 years with the range of 18-37 years. The mean BMI was 25.7±3.6 with the range of 18-31. The mean urea in the first, second and third trimester was 13.4, 13.9 and 13.2 mg/dl respectively with no statistically significant variation. The mean creatinine in the first, second and third trimester was 0.6, 0.6 and 0.5 mg/dl respectively with no statistically significant variation. To conclude, there was no significant variation of serum urea and creatinine during three trimesters of pregnancy in healthy pregnant women.
RESULTS AND PROSPECTS OF THE FIRST RUSSIAN NATIONAL AND PRACTICAL CONFERENCE «SIBERIAN CHILDREN’S LITERATURE AND READING PRACTICES IN SIBERIA» (IRKUTSK–TOMSK, SEPTEMBER 11–12, 2020)
Authors: Полева Елена Александровна , Ходина Елена Юрьевна
Published: February 2021

Введение. Подводятся итоги научной конференции, посвященной изучению проблематики и поэтики региональной детской литературы и вопросов чтения детей и подростков.
Цель – дать представление о содержании работы I Всероссийской научно-практической конференции «Сибирская детская литература и практики чтения в Сибири».
Материал и методы. Экспертное описание и анализ.
Результаты и обсуждение. Приведен обзор докладов участников конференции. Обозначены векторы диалога между специалистами разных культурно-образовательных, социальных, коммерческих институтов (вузы, библиотеки, школы, некоммерческие организации, книжные магазины) о детской литературе и чтении. Анализ содержания докладов участников конференции позволил определить актуальные задачи изучения детской и подростковой литературы (прежде всего, региональной), формы и способы приобщения детей и подростков к чтению, повышения культуры чтения в современных социокультурных условиях.
Заключение. Намечены перспективы междисциплинарного изучения сибирской литературы для детей и подростков и практик чтения.

Introduction. The article summarizes the results of a scientific conference devoted to the study of the problems and poetics of regional children’s literature and reading issues for children and adolescents.
The purpose is to give an idea of the content of the First Russian national scientific and practical conference «Siberian Ehildren’s Literature and Reading Practices in Siberia».
Material and methods. Еxpert description and analysis.
Results and discussion. The article provides an overview of the conference participants’ reports, identifies the vectors of dialogue between specialists from various cultural, educational, social, and commercial institutions (universities, libraries, schools, non-profit organizations, and bookstores) about children’s literature and reading. Analysis of the content of the conference participants’ reports made it possible to determine the actual tasks of studying children’s and adolescent literature (primarily regional), forms and methods of introducing children and teenagers to reading, and improving the culture of reading in modern socio-cultural conditions.
In conclusion, the prospects of interdisciplinary study of Siberian literature for children and teenagers and reading practices are outlined.
Improving Safety of the Aspiration and Ventilation Systems by Cleaning Air Ducts
Authors:   Krivoy Rog National University, Gurin A.A. , Shapovalov V.A. ,   Krivoy Rog National University, Lyashenko V.I. ,   GP «UkrNIPII promtekhnologii»
Published: February 2021

Aspiration and ventilation systems are an integral part of the infrastructure of industrial enterprises in various sectors of the modern economy. Reliable and efficient operation of these systems directly depends on the cleanliness of the internal surfaces of the pipelines which are part of them. The processes of corrosion and formation of deposits on the pipelines internal surfaces are irreversible. They often lead to violating the modes and parameters of the aspiration and ventilation systems work, and in some cases — to the breakage of air ducts and their fall on the equipment and people. When studying, systematizing, and generalizing the methods of pipelines cleaning, the results were used related to the analysis of domestic and foreign scientific developments, targeted-oriented on-site investigations of the air ducts of aspiration and ventilation systems, as well as our own experimental studies conducted using standard and new original methods of leading experts in this field from around the world with their participation. The possibility and efficiency of using shock air waves generated by electric discharges from high-voltage sources to destroy rust and harmful deposits and separate them from the walls of air ducts were experimentally proved. It is scientifically justified that the introduction of the proposed method for cleaning the internal walls of air ducts significantly increases the reliability and efficiency of aspiration and ventilation systems used in various branches of industry, as well as expands their technological capabilities, allowing cleaning of the complex configuration pipelines. Promising areas are identified concerning further research of technologies and technical means for removing dust deposits and rust from the internal walls of the complex configuration pipelines of aspiration and ventilation systems.
Simulation of a Breathing Apparatus on Chemically Bound Oxygen with a Circular Pendulum Circuit of the Air Duct Part
Authors:   Polotsk State University, Ekhilevskiy S.G. , Golubeva O.V. ,   Polotsk State University, Potapenko E.P. ,   Production republican unitary enterprise «Vitebskoblgaz»
Published: February 2021

At present, the main prospects for improving the insulating means of respiratory protection are associated with the chemical method of oxygen reservation. The arguments in favor of this choice are the high packing density of oxygen and its self-regulating supply, depending on the physical activity of a person. The main schemes of the air duct part of breathing apparatus on chemically bound oxygen are circular and pendulum. The attempt is made in the article to combine the advantages of the circular (small harmful space) and pendulum (small volume of the dead layer) schemes of breathing apparatus on chemically bound oxygen. For these purposes, the formalism method was developed, which allows mathematically and with the help of a computer to simulate the dynamic sorption activity of the regenerative cartridge of a breathing apparatus with a hybrid (circular-pendulum) scheme of the air duct part. The increase in the protective action of the apparatus is determined due to the use of the resource of the dead sorbent layer in the result of the air flow reverse in the pendulum part of the regenerative cartridge. Feasibility of using a hybrid scheme in the self-rescuers with a short period of protective action is shown. The optimal length of the pendulum part is determined, at which the breathing resistance decreases, and the harmful space occupied by the air returning for inhalation without contact with the unreacted layers of the oxygen-containing product is not increased. Its weak dependence on the total length of the regenerative cartridge and the maximum permissible concentration of carbon dioxide in the air returning to inhalation is shown, which makes the circular pendulum scheme realizable in practice.
Improving Safety when Extracting Water-soluble Ores by Optimizing the Parameters of the Backfill Mass
Authors:   NITU «MISiS», Khayrutdinov M.M. , Kongar-Syuryun Ch.B. ,   NITU «MISiS», Khayrutdinov A.M. ,   NITU «MISiS», Tyulyaeva Yu.S. ,   NITU «MISiS»
Published: February 2021

The results of the scientific and research work devoted to modeling the stress-strain state of the mining system of an underground mine using the finite element method in the FLAC3D software are presented in the article. The possibility of using room-and-pillar mining with backfill with the abandonment of chain pillars is justified. The results are presented concerning the research results of the quantitative assessment of the mass using the von Mises equation and Norton' power law of creep to estimate the contour stress. It becomes possible to determine the sequence of mining of the deposit area and the stage-by-stage filling of the stopes at the stage of mining design due to the high accuracy of modeling the stress-strain state of the mass near mining operations using FLAC3D software. The proposed approach is possible when evaluating the geotechnical state of the rock mass when using the mining systems with various methods of support of the mined-out area: natural; artificial; with the collapse of ores and enclosing rocks, as well as when calculating the combined method of deposit development. A differentiated approach to assessing the state of the mass is possible considering difficult mining and geological conditions, conditions of increased rock pressure, abundant water influx, increased fracturing of rocks by introducing additional conditions into the model depending on its geotechnical state. Variant of the comprehensive exploitation of mineral resources was proposed considering the total value of natural and man-made geo-resources of the area being mined. The possibility of rational use of the mined-out space with the use of various positive qualities of geo-resources at their manmade transformation is also considered. An assessment of the mineral and raw materials potential of the mined area is given with a proposal for the prospects of increasing the integrated approach of excavation, increasing the life of the mining enterprise and the complexity of developing this area.
Local Natural Ventilation Registration while Ensuring Aerological Safety at the Mining Enterprises
Authors:   NITU «MISiS», Kobylkin S.S. , Khubieva V.M. ,   NITU «MISiS»
Published: February 2021

Safety of mining operations is the basis for the efficient functioning of the mines. During mining operations, due to changing conditions in the mine workings, the natural draft began to appear more frequent. Moreover, its influence can be limited to a separate section without affecting the entire ventilation network. In this paper, the new concept is introduced and explained — local natural ventilation. The classification signs and the negative consequences of its manifestation are presented. Main difference between the local natural ventilation as a subspecies of natural ventilation as a whole lies in the limited action both in the spaces of mine workings or individual sections, and in time. Particularly its occurrence depends on the season or the technological processes performed. In this case, the local natural ventilation is not an emergency and is not subject to registration as an incident or accident. However, its manifestations can lead to both incidents and accidents. Taking this factor into account will allow to increase the level of aerological safety at the mining enterprises. A method of three-dimensional computer modeling is proposed for predicting the manifestation of local natural ventilation and making decisions to prevent it. An example of the use of this approach at the Norilsk mine during the construction of shafts with verification of field measurements is given. It confirms the possibility of practical application of the proposed calculation method. The algorithm for registering the local natural ventilation considered in the article makes it possible to develop activities for improving the level of industrial safety at the mining enterprises as a whole.
Problems in Electric Systems Caused by Harmonics and Solution Proposals
Authors: Metin Kemal , Ceylan Huseyin , Demirkesen Ertugrul , Canatan Kadir , Hizli Mikail
Published: February 2021

Together with globalization, factories, companies and even countries can survive by competing with their rivals. Nowadays, technological superiority is one of the most important factors determining competitive power. This situation causes the result of rapid change and development of technology. Due to improvement in technology, humanity dependence on electricity is increasing day by day. Many new devices get in our lives, and both the continuity and quality of electricity comes across as an important issue. Different researches are carried out to make the energy more qualified and efficient. In terms of the stability of the used electrical devices, it is important to keep the harmonic amount in electrical energy under a certain value. Besides this, these unwanted harmonics cause additional energy losses in the energy system and negatively affect energy efficiency, which is an economically important problem. In this exercise, the problems in electrical systems, the damages in electrical devices caused by harmonics have been researched and various solution suggestions have been developed for this problem.
Programas federais em alfabetização: abordagem linguístico-epistemológica
Authors: Abdala Martins Laiana , Cerutti-Rizzatti Mary Elizabeth
Published: February 2021

O objeto deste artigo é a formação continuada em alfabetização, delimitandose aos programas Pró-Letramento Linguagem (PL), vigente de 2005 a 2012, e Pacto Nacional pela Alfabetização na Idade Certa (Pnaic), iniciado em 2013, tendo entre os seus objetivos garantir que todos os estudantes estivessem alfabetizados até os 8 anos de idade, ao final do terceiro ano do ensino fundamental. A análise visa relacionar esses programas sob o ponto de vista filosófico-epistemológico em enfoque linguístico. A teoria contempla o Movimento A: enfoque cognitivo-sistêmico e o Movimento B: enfoque na interação social, cada um com duas subdivisões. À luz deles, empreende-se pesquisa documental do Manual do PL e dos Cadernos do Pnaic, que resulta na compreensão de que o PL se caracterizou por uma busca, ainda difusa,de manutenção no Movimento B, enquanto o Pnaic parece sublinhar o Movimento A1: enfoque processual-sistêmico. Os dois programas, porém, convergem no reconhecimento de que ambos os movimentos não podem ser dissociados da formação continuada de alfabetizadores.
Orientações e propostas avaliativas para a escrita alfabética no Programa Nacional do Livro Didático de 2007 a 2016: o que sugerem as coleções de alfabetização?
Authors: Do Carmo Silva Magna
Published: February 2021

Com o objetivo de verificar se as alterações no tempo de alfabetização implicaram mudanças nas propostas de avaliação para a escrita alfabética, foram analisados o Manual do Professor e o Livro do Aluno de duas coleções de alfabetização aprovadas no Programa Nacional do Livro Didático (PNLD) de 2007 a 2016. Ametodologia foi a análise temática de conteúdo. Os resultados indicaram que as coleções apresentam poucas contribuições ao professor quanto à avaliação da escrita alfabética, apesar de considerarem a avaliação como um processo de regulação da prática pedagógica. A conclusão indica que as poucas orientações sobre a forma de registro do processo avaliativo podem fomentar ações docentes que articulem ensino, aprendizagem e avaliação na perspectiva formativa e reguladora da avaliação, considerando os seguintes aspectos: elaboração de critérios avaliativos; utilização de instrumentos adequados; consideração dos erros e dos diversos conhecimentos apresentados pelos alunos; e intervenção junto aos alunos durante e após o processo de ensino.
Reflexões sobre especificidades didático-pedagógicas dos itens de leitura da avaliação da alfabetização no Brasil
Authors: Rocha Gladys , Fontes-Martins Raquel Márcia , Eleutério Miranda Vanessa Regina
Published: February 2021

Duas avaliações externas em alfabetização foram analisadas no contexto da sua implementação e, principalmente, refletindo sobre seus percursos e especificidades didático-pedagógicas: o Programa de Avaliação da Alfabetização do Estado de Minas Gerais (Proalfa) e a Provinha Brasil. Realizou-se uma pesquisabibliográfica, bem como um levantamento e uma análise de dados dessas avaliações, que permitiram considerar diferentes estratégias na elaboração, aplicação e análise dos itens destinados a avaliar a alfabetização. Há dois tipos de itens: os de modelo único, totalmente lidos pelos alunos, e os de modelo híbrido, parcial ou totalmente lidos pelo aplicador. Os itens de modelo híbrido contribuem para captar informação de estudantes leitores e também de não leitores, o que reflete na identificação de diferentes perfis de aprendizado na alfabetização. Concluiu-se que os modos de construção dos itens fundamentam-se em uma concepção de alfabetização e letramento, conceito que influencia tanto na sua elaboração quanto na seleção para os testes.
Gestão democrática e participação na decisão nas escolas: análise das legislações das redes municipais do estado do Rio de Janeiro
Authors: Vichiett Morgan Karine , Patti do Amaral Daniela
Published: February 2021

A gestão democrática é um princípio da educação pública, inscrita na meta 19 do Plano Nacional de Educação (PNE 2014-2024). Na perspectiva de pensar uma escola com vivências democráticas, os colegiados de participação e decisão constituem espaços para a materialização dessas vivências em busca de uma educação de qualidade. Para compreender o cenário das instâncias de colegialidade nas escolas, buscaram-se legislações que regulamentaram a gestão democrática nos 92 municípios do estado do Rio de Janeiro, instituídas após 2014. Localizadas 40 legislações, foram selecionadas 12 para análise, de modo a investigar como se configuram conselhos escolares, grêmios estudantis e associações de apoio à escola. Os resultados iniciais indicam movimentos fragmentados para regulamentação da gestão democrática, além da necessidade de aprofundamento empírico e teórico para a compreensão das instâncias de colegialidade e participação da comunidade escolar com vistas a uma educação de qualidade.
Ética y calidad de la educación en tiempos de la Covid-19
Authors: Losada-Sierra Manuel
Published: February 2021

A partir de la experiencia con la pandemia de Covid-19, que mostró la condición de vulnerabilidad de los seres humanos, este artículo señala que los conceptos de calidad unidos a los sistemas de gestión de calidad y la búsqueda de la excelencia no responden suficientemente al reto de formar seres humanos con la capacidad para sentir con otros y para colaborar por encima de intereses personales y deseos de éxito. Esta pertenencia a una comunidad devela la condición frágil del ser humano, así como la necesidad de los demás para enfrentar con éxito las condiciones de riesgo, como es el hecho coyuntural de esta pandemia global. Desde la propuesta ética de Judith Butler, este artículo propone tener en cuenta la condición vulnerable del ser humano como camino para educar en el cuidado de los otros y del entorno. Por último, se concluye que reconocer y tener en cuenta esta condición de imperfección es el camino para responder al individualismo que se genera cuando se enfatiza la perfección individual y la obtención de resultados.
Educação de qualidade
Authors: Fernandes Dourado Luiz , Bastos Costa de Oliveira Rafael
Published: February 2021

Entrevista com o professor Dr. Luiz Fernandes Dourado sobre educação de qualidade.
The Construction of a Database with the Pupils of the Greek Catholic High School in Beiuș and the Geographic Visualization of their Birthplace (1876/1877 School Year)
Authors: Haiduc Alexandru-Augustin
Published: February 2021

The article discusses the implementation of a database presenting the pupils that studied at the Greek Catholic High School in Beiuș in the 1876/1877 school year and presents a series of geographic annotations made on a map of the Habsburg Empire, opened in QGIS, consisting in the birthplaces of the aforementioned pupils. The database and the geographic annotations presented here are already being developed to include further pupils that studied at the Greek Catholic High School in Beiuș subsequent to the 1876/1877 school year. Therefore, the database and the geographic annotations are a pilot version of a broader project meant to conclude into a monograph regarding the Greek Catholic High School in Beiuș in the 19th century and first quarter of the 20th century.

Keywords: database, Airtable, QGIS, Beiuș, high school, 1876/1877 school year
POLITICAL BOUNDEDNESS AND THE ROLE OF CARTOGRAPHY
Authors: HABBARD Anne-Christine
Published: February 2021

I will question the legitimacy of borders via its underlying premise: the supposedly natural boundedness of communities. Two avenues are usually used to show the legitimacy and necessity of borders: either as a way to protect and preserve the conception of the good and the values of an already existing bounded community; or as a way to create a democratic polity, the limits of which are required to uphold the rights of citizens. Either way, what is presupposed is that communities are and/or should be bounded. I will argue that the arguments in favour of political boundedness do not hold up to scrutiny, least of all in the form of territorial borders. This will lead me to a discussion on the precedence of the graphic gesture of drawing the line, and hence on the violence of boundary-making.
LANGUAGE AND PUBLICS IN A GLOBAL DIGITAL WORLD. WHAT IS LINGUISTIC CITIZENSHIP IN THE 21ST CENTURY?
Authors: SCHNEIDER Britta
Published: February 2021

In this article, I discuss language from a linguistic anthropological perspective, where the existence of standardised languages is understood as an outcome of socio-political discourses in the age of nationalism, in which the technologies of print literacy enabled national public spaces – and with it, national language standards – to emerge. What happens to language standards and public spaces in the era of digital technologies and transnational interaction? I introduce some examples and develop ideas on language policing in settings where monolingual national ideals exist besides other emerging linguistic authorities.
RADIO ROMANIA INTERNATIONAL – A JOURNALISTIC TOOL TO CROSS BORDERS
Authors: COJOCARIU Eugen-Adrian
Published: February 2021

The paper analyzes how international broadcasters cross all types of borders, physical or conceptual, in order to reach the public and fulfill their role of public diplomacy tool for their countries in a difficult context for international stations and for media in general. We focused on Radio Romania International, which produces and broadcasts programs in 13 languages, aiming at promoting Romania, its domestic and foreign policy.
‘WITH WHOM WE TALK?’ DRAWING REGIONS IN 21ST CENTURY AFRICA
Authors: BLIDARU Mădălin-Cătălin
Published: February 2021

The African continent inherited borders drawn by foreign actors for centuries, with a limited influence exerted by its internal political structures. This impacted its development across decades, acting as a contributing factor to economic, social and political conflicts, some of them resulting in further divisions in time: new states emerged, while the federal structures developed within some states remain unstable.
In this paper, the author investigates the current regional groupings of states established in different African frameworks in an attempt to answer the question “how external actors influence and legitimize the development of regions” in 21st century. From a functionalist perspective, it explores the motives for the formation of a wide range of regional integration and cooperation organizations. The case study of G5 Sahel, an institutionalized regional arrangement focused on security and development of its member states, is analyzed as an arrangement emerged with support from France and the European Union. The case study analysis trails the cooperation with these two foreign actors with the G5 Sahel member states in the five years, focused on evolution, financing and joint initiatives – including to what extent these contributed to consolidation of the regional borders.
CONSEQUENCES DE CHOIX METHODOLOGIQUES SUR L’ANALYSE DE L’EVOLUTION DE L’ORGANISATION CLANDESTINE ETA
Authors: GUIBET LAFAYE Caroline , BROCHARD Pierre
Published: February 2021

Consequences of Methodological Choices on the Analysis of the Clandestine Organisation ETA. Born in December 1958, Euskadi Ta Askatasuna (ETA) was dissolved on May, 11th 2018. During its almost sixty years of existence, ETA has undergone phases of military offensive and then a decline in its operational activity. In order to understand the limits of these episodes and their reasons, we have created an original database listing all the actions of the armed group. Its analysis contributes to highlight the strategic developments of the clandestine organisation and makes possible to discuss the conclusions previously drawn from the group’s databases of fatal victims. We will thus consider the consequences of methodological choices on the interpretation the history of a clandestine organisation and of its key moments.
Libro Delta Δ: El primer léxico filosófico
Authors: Ramírez Daza y García Rómulo
Published: February 2021

En la presente investigación se destaca la importancia del quinto libro de la Metafísica de Aristóteles, muchas veces ignorada en los planteamientos de fondo de la metafísica aristotélica, para lograr una comprensión más expedita del proyecto que representa su filosofía primera. Se estudia este extraño texto del Estagirita, como un entresijo en la ordenación clásica que insertó originalmente la edición de Andrónico de Rodas, y tal como han llegado hasta nosotros los textos de dicho proyecto aristotélico. Se resalta la interpretación del Comentario de Alejandro de Afrodisias como una de las principales autoridades dentro de la historia del aristotelismo que han hecho patente la relevancia del libro Delta. Y se explica la significación que tiene la aportación aristotélica al haber escrito, por vez primera y sin parangón alguno, el primer léxico filosófico para la posteridad, problematizando su supuesta incompletitud. La presente investigación se centra más en la forma textual y en su significación de conjunto, que en la exposición de sus contenidos puntuales.
Factors of International Activity of Russian Cities: The Results of the Empirical Analysis
Authors: Mukhametov R. S.
Published: February 2021

The international activities of governments at the subnational level have become widespread practice. Cooperation between local authorities, which began in Europe with the aim of promoting peace, international understanding, and reconciliation between peoples in the post-war period, has spread throughout the world over time. International cityto- city partnerships, also known as sister cities, have become an instrument for promoting economic development. The movement of sister cities is considered not only as a form of cross-border intermunicipal cooperation, but also as one of the aspects of paradiplomacy. One of the consequences of regionalization that swept post-Soviet Russia in the 1990s was the growth of foreign economic activity, international contacts of both Russian regions and cities. This is reflected in the signing of intermunicipal agreements. This research is aimed at determining the factors on which the international activity of Russian cities depends. The theoretical and methodological basis of the work was the concept of paradiplomacy in general and city diplomacy in particular. The author put forward several hypotheses in the framework of the approaches to high international activity of cities existing in the scientific literature. The database was a list of sister cities, including 150 Russian municipalities compiled by the International Association of Related Cities. Statistical calculations were performed by multiple linear regression. As a result of the study, it was found that a large number of sister cities are observed in Russian cities, which can be attributed to megacities and large cities. It was revealed that a high level of international activity of Russian cities is characteristic of municipalities located in border regions. It is shown that economic characteristics directly affect the number of contracts. The author came to the conclusion that the status of the administrative center of Russian regions positively affects on the number of sister cities. The article emphasizes the influence of the historical heritage of territories on the development of inter-municipal cultural cooperation. In conclusion, it is noted that the influence of demographic, geographical, economic, political, legal, and cultural-historical features of municipalities on the number of sister cities does not explain all cases. The author believes that the political factor has a certain explanatory power.
Investigation of the Anti-cataract and Antioxidant Activities of Cnidoscolus aconitifolius Leaves Extract In vitro
Authors: Bulama Henry , Dahiru Daniel , Madu Joshua
Published: February 2021

Background: Cataract is a major cause of visual impairment and blindness around the world. This study evaluated the in vitro antioxidant and anti-cataract activities of Cnidoscolus aconitifolius leaves extract and fractions. Antioxidant activities were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azinobis (3-ethylbenzothiozoline-6-sulfonic acid) (ABTS), total reducing power, and hydrogen peroxide scavenging assays. Anti-cataract potential was evaluated in vitro using goat lenses divided into eight groups of different treatments and incubated in artificial aqueous humor at 37 Â°C for 72 hours. Glucose-induced opacity in the lenses was observed and biochemical indices quantified (catalase, Malondialdehyde (MDA) and total protein in the lens homogenate).

Results: The crude extract and its fractions possess substantial antioxidant activities. The aqueous fraction exhibited the best DPPH radical scavenging activity (IC50 value 78.599 Âµg/ml); while the dichloromethane fraction exhibited the highest ABTS radical scavenging activity with IC50 66.68 Âµg/ml. The anti-cataract evaluation of crude and fractions at 250 Î¼g/ml showed a significant increase (p<0.05) in the total protein and catalase activity compared to the cataract control group. The malonaldehyde level decreased significantly (p<0.05) in all the treated groups.
Survey of Human Face Mites Demodex Owen, 1843 (Acari, Demodicidae) in Patients with Blepharitis and Chalazia in Iraq
Authors: Bedair Basma H. , Salman Suhaila D.
Published: February 2021

Demodex species are external parasites; they are transmitted via direct contact, and when present in elevated numbers it may induce several ocular diseases. However, the symptoms are very similar to other diseases; hence, itsâ€™ role is often neglected. Therefore, an accurate diagnosis is important in order to avoid mistreatment. In this study, infestation rates in both blepharitis and chalazia were compared to an asymptomatic group, with relation to gender, age, personal hygiene, time of year, and residency. All specimens were examined immediately after collection. The aim of this study was to investigate the relationship between Demodex mites and ocular diseases. These mites were predominantly found in patients with chalazia (62.50%) followed by blepharitis (58.91%), while they were only observed in (22.64%) of asymptomatic patients, statistical analysis showed a significant relationship between infestation and both ocular diseases (P<0.01). The infestation rates increased significantly with age reaching (100%) in patients above 70 years old, and especially during cold months with high humidity. These mites were also found in rural areas (57.59%), followed by urban areas (44.09%) and a significant relationship was found between residency and infestation rate (Pâ‰¤0.05). However, no significant relationship was found according to gender nor personal hygiene.