bluuebunny/crossref_metadata_2025 huggingface dataset:
Barreiras e facilitadores para a prática de atividade física em diferentes domínios no Brasil: uma revisão sistemática
Authors: Christofoletti Marina , Streit Inês Amanda , Garcia Leandro Martin Totaro , Mendonça Gerfeson , Benedetti Tânia Rosane Bertoldo , Papini Camila Bosquiero , Borges Lucélia Justino , Binotto Maria Angélica , Silva-Júnior Fernando Lopes e
Published: August 2022

Resumo O objetivo foi revisar sistematicamente as evidências científicas sobre as barreiras e os facilitadores para a prática de atividade física (AF) na população brasileira, considerando os diferentes domínios (lazer, deslocamento, trabalho/estudo e tarefas domésticas). A busca foi conduzida nas bases de dados MEDLINE/PubMed, ISI Web of Science, Scopus, BIREME/LILACS e APA PsycNET, considerando o período de 2010 a 2020. Posteriormente, foi incluída a busca na Revista Brasileira de Atividade Física e Saúde. O processo de seleção consistiu na leitura de títulos e resumos, seguida de textos na íntegra. A avaliação foi realizada por pares e, mediante discrepância, um terceiro revisor era consultado. O domínio do lazer e as barreiras e os facilitadores ambientais foram os mais investigados nos 78 artigos incluídos. Houve consistência nas associações positivas de seis diferentes facilitadores pessoais e sociais para o lazer e um fator ambiental para o deslocamento. Encontrou-se um número reduzido de investigações sobre os domínios de trabalho/estudo e tarefas domésticas, sendo importante o incentivo a futuras investigações acerca das barreiras e dos facilitadores pessoais e sociais relacionados à AF de deslocamento.
O Lazareto da Jurujuba na imprensa do Rio de Janeiro oitocentista: “logar mais proprio para estender redes de pescarias que para fundar-se um tal estabelecimento”
Authors: Fonseca Maria Rachel Fróes da
Published: August 2022

Resumo Na segunda metade do século XIX, o periodismo expandiu-se e alcançou grande variedade temática e de público, e era constituído pelos jornais diários, que se dedicavam especialmente ao cotidiano da cidade, e pelas revistas científico-literárias, que veiculavam textos de temáticas diversas, como literatura, biografia, ciências e educação. Nas páginas dos inúmeros periódicos que circulavam no Rio de Janeiro, tanto dos chamados jornais diários quanto dos periódicos científico-literários, evidenciou-se grande interesse pelas temáticas da higiene, da salubridade, da epidemia de febre amarela, das medidas higiênicas e da atuação dos médicos. Entre as medidas sanitárias adotadas, foi instalado em 1º de janeiro de 1851, por orientação de Francisco de Paula Cândido, presidente da Junta de Higiene Pública, um lazareto para cerca de 30 enfermos em uma casa alugada na península do Caju, no Saco da Jurujuba, em Niterói, na província do Rio de Janeiro, e então denominado Lazareto da Jurujuba. Buscamos neste estudo analisar o conteúdo de matérias e comunicados sobre as condições e medidas sanitárias do Rio de Janeiro, especialmente sobre a criação do Lazareto da Jurujuba, publicados nos jornais diários e na imprensa não especializada.
The Lazarette of Jurujuba in the nineteenth-century Rio de Janeiro press: “a better place to spread fishing nets than to found such an establishment”
Authors: Fonseca Maria Rachel Fróes da
Published: August 2022

Abstract In the second half of the nineteenth century, the press expanded and reached a wide range of themes and audiences. It consisted of daily newspapers, which were especially dedicated to the daily life of the city, and scientific-literary magazines, which published texts on a wide range of themes, including literature, biography, science, and education. In the pages of the numerous periodicals that circulated around Rio de Janeiro, both the so-called daily newspapers and the scientific-literary periodicals, there was a great interest in the themes of hygiene, salubrity, the yellow fever epidemic, hygiene, and the performance of doctors. Among these sanitation measures, adopted on January 1, 1851, under the guidance of Francisco de Paula Cândido, president of the Junta de Higiene Pública (Public Hygiene Board), a lazarette for about 30 sick people was installed in a rented house on the Caju peninsula, in Saco da Jurujuba, in Niterói, in the province of Rio de Janeiro, and then called Lazareto da Jurujuba (Lazarette of Jurujuba). The present study thus sought to analyze the content of articles and announcements about the sanitary conditions and measures in Rio de Janeiro, especially concerning the creation of the Lazareto da Jurujuba (Lazarette of Jurujuba), published in daily newspapers, and in the non-specialized press.
COVID-19 in prisons: what telejournalism (not) showed - a study on the criteria for newsworthiness during the pandemic
Authors: Diuana Felipe A. , Diuana Vilma , Constantino Patricia , Larouzé Bernard , Sanchez Alexandra
Published: August 2022

Abstract To analyze the news coverage of the COVID-19 pandemic in Brazilian prisons and its visibility, 213 articles broadcast between March and December 2020 were examined, found in the search service of the digital streaming video platform Globoplay. Most aired in March, April and July, with the theme almost disappearing in subsequent months. The reports, on numbers of deaths or infections, prevention measures and house arrest or freedom for groups at risk of COVID-19 were mainly published in local telejournals. Health agencies were barely heard. Of the 19 news items presented nationally, 12 address “famous prisoners” and the legibility of house arrest or freedom for groups at risk of COVID-19 unfavorable outcome. The health guidelines and the guarantee of the right to health of persons deprived of liberty were limited to the difficulties in implementing protection measures in prisons and to sustaining the need for restrictive measures to move inside prisons and in exchanges with the outside, to limit the circulation of the virus. In general, the form and visibility given to the topic do not contribute to broadening the viewers’ perception of the sanitary conditions in prisons and the fact that health is a right for all, without any distinction.
Characterization of primary health care for patients with diabetes based on the PMAQ-AB
Authors: Muzy Jéssica , Campos Mônica , Emmerick Isabel , Avelar Fernando Genovez de
Published: August 2022

Abstract This article aims to present a proposal for making the instruments used in the three cycles of the PMAQ-AB compatible and to analyze the information on access, coverage, structure, organization and provision of services in PHC related to care for DM in Brazil, according to regions, from the perspective of family health professionals and users. We performed an analysis of the degree of compatibility of the PMAQ-AB questions (2012, 2014 and 2017). To analyze the temporal evolution of the components, we performed a proportion difference test. We calculated the percentage difference between the perspective of professionals and users, per year analyzed, for Brazil. In general, there was an improvement in the quality of care and examinations, except for the diabetic foot. Worse results were found for the North region in relation to the other regions. Despite the structural improvement and the quality of care reported by professionals, there are significant gaps in the quality of care for patients with DM in the SUS. In the scenario of scarce investment added to the growing prevalence of DM, obstacles become progressively more challenging. Therefore, monitoring and evaluating the quality of services provided are essential tasks of the Brazilian Health System.
Organizational justice and cardiometabolic disease: a systematic review
Authors: Scalabrin Angela , Silva Andréa Tenório Correia da , Menezes Paulo Rossi
Published: August 2022

Abstract The effects of organizational justice on workers’ health have been investigated in several areas of work. However, the systematization of available information on the effects related to cardiovascular diseases (CVD) and diabetes is scarce. This article aims to systematically review the association between organizational justice and CVD and metabolic disease in adult workers. The search strategy included the terms organizational justice, coronary heart disease, cerebrovascular disease, systemic arterial hypertension, diabetes mellitus and CVD. This study investigated the following databases: MEDLINE, EMBASE, and LILACS. The quality of the studies was assessed using the instrument developed by the National Institute of Health. Results: This study identified 1,959 titles. After evaluation, eight studies were selected. Individuals with a high perception of organizational justice showed a lower risk of CVD and metabolic disease, whereas low organizational justice presented repercussions for the cardiovascular and metabolic health of workers. The development of strategies to promote organizational justice must be prioritized and thus mitigate its impacts on workers and institutions.
IMPACTS OF RESISTANCE TRAINING ON PHYSICAL FITNESS AND INJURY PREVENTION IN CHILDREN AND ADOLESCENTS
Authors: Hui Wang
Published: August 2022

ABSTRACT Introduction: An adequate physical intervention program can improve the physical level of adolescents, promoting their interest in sports learning and socialization, factors that indirectly contribute to academic performance. Despite having a positive impact on athlete performance, cardiopulmonary resistance training has received few studies related to its benefits in children and adolescents. Objective: Explore the effect of resistance training on the physical fitness of children and adolescents and the prevention of their sports injuries. Methods: The statistical method was used in a situational analysis of injuries in different sports of 455 young people. In a second moment, 20 volunteers divided into groups by sex were submitted to resistance training exercises involving aerobic (30 minutes) and anaerobic (15 minutes) activity, under 45 minutes daily, three times a week, for ten weeks. Pertinent data were collected before, during, and after the intervention. They were submitted for analysis and consideration and performed statistical treatment on the data. Results: The frequency of sports injuries in adolescents was high, especially the mild injuries related to the characteristics of adolescents. Under the same intensity of resistance training, there was an improvement in running performance. There was a significant improvement in lung capacity, with relatively small differences between males and females. Conclusion: Resistance training can effectively improve the fitness level of children and adolescents, and its promotion is strongly recommended. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
BENEFITS OF RUNNING ON CARDIAC PROTECTION AND THE CULTURE OF EXERCISE HEALTH AWARENESS
Authors: Tao Chen
Published: August 2022

ABSTRACT Introduction: Several programs to encourage physical activity has been encouraged to reduce the sedentary lifestyle in China. Running is among them because it has potentially positive effects on cardiovascular diseases, hypertension, diabetes mellitus, and hypercholesterolemia, in addition to the intrinsic psychological and social benefits of outdoor sports. Objective: Explore the protective effect of running on the cardiac system by analyzing strategies for cultivating exercise health awareness. Methods: A group of ten healthy volunteers, five women aged 25-35 years, underwent a 45-minute running program, performed four times a week for three weeks. Data collected by spirometry and cardiac monitoring were collected, treated, compared, and discussed. This paper introduced the concept of subjective exercise intensity to find the best analysis and judgment of Cardiac Function. Finally, a quantitative investigation involving the analysis of 315 questionnaires explored the current status of sports health awareness in running fans. Results: Heart rate amplitude during running remained in the range of 120-160, belonging to the normal heart rate range for the surveyed audience. In most cases, women's heart rate was higher than men's (P<0.05). The exercise intensity was fixed at a frequency below the value of 16, which is a slightly strenuous stage, and the relative exercise intensity was controlled between 50% and 71.5%. Conclusion: Running has a good cardiac protective effect, and its followers are highly aware of sports health. Due to the beneficial effect of sports practice, its dissemination is recommended as a form of physical and social therapeutic activity. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
PREVENTION OF KNEE INJURIES USING TEAM SPORTS IN THE AGED POPULATION
Authors: Pan Feng
Published: August 2022

ABSTRACT Introduction: The aging population in the growing national industrialization and urbanization supports an unhealthy lifestyle where the prevention and control of chronic diseases are difficult. Approximately 68% of the elderly have some type of chronic disease, mostly musculoskeletal, especially in the knee joint, compromising their autonomy and affecting their social life, with psychological impacts in the long term. Team sports suggest great therapeutic potential in this group, but there are few studies. Objective: Analyze the situation of team sports among the elderly, propose methods to prevent knee joint injuries, and test these implements’ preventive effects. Methods: 92 elderly volunteers who participated in community sports were selected. To understand the causes and main types of knee joint injuries, the elderly were analyzed during community sports, including using the FMS method for health testing. Results: After the tests, it can be seen that the mean FMS score of all the community elderly is 14.23 points, and the total score is 12.00-17.00; the mean score of the overall knee joint injury is increased by 2.65, and the mean FMS score of the female knee joint injury is greatly benefited. Conclusion: After the proposed preventive measures focused on the knee joint, the AFF examinations of the community elderly were significantly improved, indicating that the proposed actions are effective and deserve to be replicated. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
Study of innovation capacity of fisheries companies in the covid-19 pandemic crisis
Authors: Dehyouri S. , Zand A. , Arfaee M.
Published: August 2022

Abstract Many countries have encountered coronavirus pandemic crisis around the world. Through the outbreak of this disease in Iran, preventive plans have been implemented to break the chain of the disease infection. These measures in the economic sector have affected supply, production and demand, and to some extent have led to the partial or complete closure of some businesses and occupations. In the context, it seems that innovative an “innovation capacity” infrastructure measures and turning to innovation in this crisis can be a strategy to moderate and optimize the situation. This study tries to design concepts of the fisheries firms’ innovation capacity model in the context of the COVID-19 pandemic crisis. After collecting data, they were analyzed using SPSS and PLS SMART software, which were performed in two parts: descriptive statistics and analytical or inferential statistics. A novel research model is presented to examine the impact of factors such as innovation management, social, cultural, human and organizational capital, crisis strategies, government actions in crisis situations, and marketing strategies in crisis situations, as well as, recognition and application of marketing advantages in crisis situations, which offers a re-analysis of innovation capacity. According to the results, among the variables played a significant role on the level of innovation capacity in epidemic conditions, innovation management (p> 0.000; β = 0.593), and recognition and application of marketing advantages (p> 0.049; β = 0.209) were the most significant, independent variables affecting the innovation capacity, which explained its variations.
The concurrent accuracy of the modified telephone interview for cognitive status and mini-mental state examination tools in detection of cognitive impairment among older adults
Authors: Laghousi Delara , Aminisani Nayyereh , Shamshirgaran Seyed Morteza , Javadpour Ali , Gholamnezhad Zahra , Gilani Neda , Asghari-Jafarabadi Mohammad , Alpass Fiona
Published: August 2022

ABSTRACT. Due to the need for face-to-face administration of many cognitive screening tests, it is not always feasible to screen large-scale samples. Objective: This study aimed to assess the discriminant validity of the Persian version of Telephone Interview for Cognitive Status (P-TICS-m) and Mini-Mental State Examination in the middle-aged Iranian population. Methods: The P-TICS-m and MMSE were administered to 210 randomly selected middle-aged community-dwelling adults who had been registered in the Neyshabur Longitudinal Study on Ageing. Participants also underwent psychological examination by two neurologists to assess cognitive impairment based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria. To evaluate the discriminant validity of P-TICS-m and MMSE with DSM-V criteria, the sensitivity, specificity, positive and negative predictive values (PPV and NPV), and positive and negative likelihood ratios (LR+ and LR−) were calculated. Results: The mean age of the participants was 59.6±6.8 years. The TICS and MMSE were highly correlated (r=0.635, p<0.001). The sensitivity, specificity, PPV, NPV, LR+, and LR− to discriminate cognitive impairment were, respectively, 83%, 92%, 68%, 96%, 10, and 0.182 for MMSE and 100%, 13%, 19%, 100%, 1.16, and 0 for TICS-m. The receiver operating characteristic curve analysis results showed no statistically significant differences between P-TICS-m and MMSE. Conclusions: Our findings indicate that the TICS-m test can be used as a screening tool instead of the MMSE. Due to the low specificity and low PPV of the TICS-m compared to MMSE, the diagnosis should be confirmed using definitive diagnostic tests when a subject is classified as having cognitive impairment.
Processo assistencial às mulheres com morbidade materna grave: um estudo misto
Authors: Villalba Jessica Paola Garcia , Pereira Adriana Lenho de Figueiredo , Queiroz Ana Beatriz Azevedo , Batista Deise Breder dos Santos , Guimarães Juliana Cristina Nascimento
Published: August 2022

RESUMO Objetivo: Descrever as características maternas e obstétricas associadas à morbidade materna grave e os fatores do processo assistencial envolvidos nesses desfechos graves segundo enfermeiras e médicos. Método: Estudo misto sequencial em maternidade terciária no município do Rio de Janeiro, a partir de registros da assistência e entrevistas com esses profissionais, de fevereiro a julho de 2019. Aplicaram-se teste qui-quadrado, razão de prevalência e análise de conteúdo temática. Resultados: Em 66 (100%) mulheres, a pré-eclâmpsia grave (77,3%) foi mais prevalente e ocorreram 12 (18,2%) casos de near miss e um óbito materno. A hemorragia pós-parto (RP= 3,21; IC 95% 1,22-8,41) e realização de transfusões sanguíneas (RP= 3,60; IC 95% 1,81-7,16) contribuíram nos desfechos graves. Há deficiências no sistema de saúde, acesso à saúde reprodutiva e qualidade da assistência. Conclusão: Melhorias no acesso à saúde e qualidade do processo assistencial são imperiosas para reduzir os desfechos maternos graves.
Cross-cultural adaptation and validation of the Urinary Incontinence Scale After Radical Prostatectomy for the Brazilian context
Authors: Mata Luciana Regina Ferreira da , Azevedo Cissa , Menezes Aline Carrilho , Chagas Sabrina de Cássia , Izidoro Lívia Cristina de Resende , Estevam Fabrícia Eduarda Baia , Chianca Tânia Couto Machado
Published: August 2022

ABSTRACT Objective: To translate, adapt, and validate the Urinary Incontinence Scale After Radical Prostatectomy for Brazil. Method: Methodological study: cross-cultural adaptation (translation, synthesis, back translation, expert committee (n=25), pre-testing (n=40) and presentation to original authors) and evaluation of measurement properties (n=80). Data were collected between January 2018 and February 2019 in an oncology unit. The calculated measurement properties: structural validity, hypothesis testing, criterion validity and reliability. Results: The Brazilian version was called Escala de Incontinência Urinária Pós-Prostatectomia Radical. One item was excluded due to low factor loading (0.322). A significant correlation was identified between the total score of the scale and instruments applied (p<0.001). Incontinent men had higher scores on the total scale in relation to continents (p<0.001). Cronbach’s alpha was 0.94 and composite reliability was 0.97. Conclusion: The Brazilian version was considered valid and reliable for the assessment of urinary incontinence in prostatectomized patients.
Eucalyptus staigeriana essential oil in the control of postharvest fungal rots and on the sensory analysis of grapes
Authors: Pedrotti Carine , Trentin Tayná Ribeiro , Cavião Hélen Corso , Vilasboa Johnatan , Scariot Fernando Joel , Echeverrigaray Sergio , Piemolini-Barreto Luciani Tatsch , Schwambach Joséli
Published: August 2022

Abstract The objective of this work was evaluate the effect of Eucalyptus staigeriana essential oil on Colletotrichum gloeosporioides and Greeneria uvicola mycelial growth and conidia germination on grapes, as well as its potential for the control of postharvest rot diseases and its effect on the organoleptic properties of grapes. The essential oil (EO) showed in vitro antifungal activity against both pathogens, with fungicidal effect on mycelial growth and on conidia germination at the concentrations of 1.0 and 0.5 μL mL−1, respectively. The EO volatile compounds had a fungistatic effect on the mycelial growth of C. gloeosporioides and a fungicidal effect on G uvicola. At postharvest, the EO reduced the incidence of ripe rot up to 75% and 86% in the preventive and curative treatments, respectively, and the incidence of bitter rot up to 54% in the curative treatment. Since the EO does not affect significantly grape sensory properties, it does not affect the consumption intention of grapes treated with the EO. The EO of E. staigeriana is efficient in the in vitro control of both pathogens; moreover, it is also efficient in the control of the incidence of postharvest fungal rot diseases, mainly in the curative treatment.
Modeling of the height-diameter relationship in eucalyptus in integrated crop-livestock systems
Authors: Kruchelski Silvano , Trautenmüller Jonathan William , Orso Gabriel Agostini , Roncatto Eduardo , Triches Gilmar Paulinho , Behling Alexandre , Moraes Anibal de
Published: August 2022

Abstract The objective of this work was to compare the height-diameter relationship, described by nonlinear biological models, in Eucalyptus benthamii in monoculture forestry and in three different integrated crop-livestock systems (ICLS): crop-forestry, livestock-forestry, and crop-livestock-forestry. The trees were evaluated during seven years after planting. Five nonlinear biological models were fitted to evaluate the height-diameter relationship, and Gompertz’s model was selected to describe the data, although all models described satisfactorily the height-diameter relationship of the trees in the ICLS. The analysis of the data showed that there is no similarity between monoculture forestry and the ICLS as to the height-diameter relationship. In addition, the height-diameter relationship in E. benthamii changes between the different ICLS. Particularly, two systems with cattle provide the same values of maximum growth rate, asymptote, and inflection point of diameter at breast height. Furthermore, with the integration of cattle into the tree component, the produced trees show lower asymptotic heights, with larger diameters when the average tree heights of the ICLS are equal.
Epidemiological assessment of factors associated with late diagnosis of HIV infection
Authors: Khasanova Gulshat R. , Agliullina Saida T. , Kruykova Lidia A. , Gilmutdinova Guliya R. , Nagimova Firaya I. , Galiullin Niyaz I.
Published: August 2022

Background. Late diagnosis of human immunodeficiency virus (HIV) infection contributes to its spread and becomes an obstacle to achieving the goal of early treatment.
Aim. To conduct an epidemiological analysis of factors associated with late diagnosis of HIV infection.
Material and methods. The study included data from 348 patients over 18 years of age living in Kazan, who were diagnosed with HIV infection for the first time in 2019. The proportion of patients with late diagnosis of HIV infection was determined. The criteria for late diagnosis were the level of CD4+-lymphocytes less than 200 cells/mm3 and/or the presence of 4 HIV stage (stage of secondary diseases) at the time of diagnosis. The assessment of the influence of probable factors on the timeliness of diagnosis was carried out using binary logistic regression. The regression model included data from 307 people who managed to determine the timeliness of diagnosis. For each factor, odds ratios were calculated (unadjusted based on the results of univariate analysis, adjusted based on the results of multivariate analysis), as well as their 95% confidence intervals.
Results. Late diagnosis of HIV infection was noted in 32.6% of cases. Examination for clinical indications was associated with late diagnosis in comparison with examination for preventive purposes (adjusted odds ratio 2.427, 95% confidence interval 1.1844.973). The age of 50 years and older was associated with late diagnosis compared with patients 3049 years of age (adjusted odds ratio 3.348, 95% confidence interval 1.5427.265).The chances of late diagnosis under the age of 30 years are 5 times lower than in the 3049 year old group (adjusted odds ratio 0.200, 95% confidence interval 0.0720.556). The odds of late diagnosis are significantly higher among people who become infected through parenteral transmission through injecting drug use compared to those who become infected through sexual (heterosexual) transmission (adjusted odds ratio 2.012, 95% confidence interval 1.0423.885).
Conclusion. In order to control the spread of HIV infection in the population, it is necessary to increase the coverage of HIV screening testing for all population groups, especially the older age group and injecting drug users.
Selectins and their involvement in the pathogenesis of cardiovascular diseases
Authors: Kalinin Roman E. , Korotkova Nataliy V. , Suchkov Igor A. , Mzhavanadze Nina D. , Ryabkov Alexander N.
Published: August 2022

The review presents current data on the structure and functional role of cell adhesion molecules belonging to the selectin family (selectins P, L and E), and their involvement in the pathogenesis of cardiovascular diseases. On the one hand, intercellular adhesion molecules of the vascular wall endothelium, platelets and leukocytes are an important link in the processes of vasculogenesis, development and regeneration of the vascular system. On the other hand, these molecules participate in the earliest stages of endothelial dysfunction with the subsequent development of pathology. For this reason, figuring out the mechanisms of activity of this group of molecules is very important for understanding the molecular basis of the cardiovascular diseases pathogenesis. The adhesion of molecules, both between cells and between cells and a component of the extracellular matrix, is the most important stage of physiological and biochemical processes. According to present knowledge, five classes of intercellular adhesion molecules are known: integrins, cadherins, immunoglobulins (including nectins), selectins and addressins. All of them are bonded to a cytoplasmic membrane and provide the interaction of cells with each other. Some of them are transmembrane and associated with the cytoskeleton of the cell. On the cell surface, intercellular adhesion molecules can be located in clusters, forming multipoint binding sites and thereby determining the degree of avidity. One of the most significant functions of selectins is participation in the initial stage of the leukocyte adhesion cascade, which results in their binding to the endothelium, rolling and further extravasation into tissues. The first stage of this process is mediated by specific non-covalent interactions between selectins and their glycan ligands, with the glycans functioning as an interface between leukocytes or cancer cells and the endothelium. Targeting these interactions remains one of the main strategies aimed at developing new methods of treating immune, inflammatory and oncological diseases.
Practical aspects of the organization of ethical review of clinical trials in the context of the COVID-19 pandemic
Authors: Nezhmetdinova Farida T. , Guryleva Marina E.
Published: August 2022

The COVID-19 pandemic has greatly affected all spheres of life, including biomedical research. The ethical regulation of clinical trials has a long history in international and domestic practice. An efficient infrastructure of international and national legislation has been created. At the same time, there are features of the organization of ethical review of clinical trials that arise under the restrictions associated with COVID-19. Healthcare of all countries is faced with the need to develop new approaches caused by the speed of the spread of the disease, its severe consequences for the life and health of people, the excessive burden on the medical worker, not only physical, but also psychological, including those associated with ethical problems. The purpose of this research was to study and analyze the experience of ethical review of clinical trials in the context of the COVID-19 epidemic, its regulatory framework in international and domestic practice. For high-quality and lawful conduct of clinical trials in Russia in the context of the COVID-19 epidemic, appropriate conditions were created, namely, a vertical base: the central ethical committee of the Ministry of Health of the Russian Federation local ethical committees based in clinical institutions and research centers. They are provided with sufficient and high-quality legal support in the form of laws of the Russian Federation, country standards and by-laws. The work of local ethics committees is built in accordance with strict ethical international and domestic standards. Standard operating procedures implemented in local ethics committees provide for all the nuances of situations, including those implemented using modern telecommunication technologies and other end-to-end information technologies. Even if many restrictions are imposed, biomedical research must continue, and accordingly, it must be carried out under the strict control and monitoring of research ethics committees. The article presents an overview of legal sources, an analysis of the main approaches in domestic and foreign literature, taking into account historical retrospective.
Development of the university's innovation assessment system at the national level
Authors: Zubarev Nikita Yu.
Published: August 2022

The paper examines approaches to the assessment of innovation activity of Russian universities and concludes that there is no unified assessment methodology and a set of relevant indicators. As a single assessment tool at the state level, it is proposed to use Monitoring the effectiveness of the activities of educational institutions of higher education. For these purposes, the author proposes to allocate an independent block of indicators in the monitoring structure that reflect the innovative activity of the university as comprehensively as possible. At the same time, part of the indicators should be transferred from the Monitoring section on the evaluation of research activities. The author supports the approach of forming a set of indicators for assessing innovation activity in three areas innovation potential, innovation activity and the effectiveness of innovation activity. At the same time, based on the legislatively fixed concept of innovation activity, the author of the article suggests that when choosing indicators for assessing innovation activity, include only indicators reflecting the effects (primarily economic) of the implementation of innovative projects and the creation (development) of innovation infrastructure. Based on the results of the analysis of currently available indicators in Monitoring, the author proposes to include additional 14 indicators in the assessment of the university's innovation activity, distributing them into the above groups, which will allow the most comprehensive assessment of this area of activity of Russian universities and conduct correct comparisons with other universities, regardless of their size.
DECONSTRUCTING MAINSTREAM DISCOURSES OF CHILD AND YOUTH DEVELOPMENT AS IT CONNECTS TO SEXUALIZED VIOLENCE AGAINST CHILDREN
Authors: Lindner Kylee , Kakuru Doris
Published: August 2022

This article reviews literature on survivors of child sexual abuse (CSA) who were preschool-aged when the abuse occurred, and applies critical discourse analysis to reveal power relations within this field of research. Utilizing themes of narrative theory, this article demonstrates how the current discourse has promoted a single story of developmental trajectories marred by entrenched deficits. The reviewed literature often utilized definitive language in describing a narrative of damage that not all survivors identify with. We critically examine this narrative as an expression of power that risks misrepresenting a large group of people. Additionally, we recommend that future research promote a discourse of multiple stories in which survivors have agency to author their own stories.
Trait Association Studies in Early Segregating Generations of Cowpea [Vigna unguiculata (L.) Walp]
Authors: Sunil R. , Joseph Jiji , Biju S. , Mathew Deepu , Beena C.
Published: August 2022

Background: Cowpea is a major pulse crop in India. Developing cowpea cultivars with high yield and sustainable protein content contributes to food and nutritional security. Hybridization followed by careful selection of genotypes from the early segregating populations may produce a final cultivar with high yield coupled with high protein content. Methods: The genetic material used in the present investigation were derived from crosses of three cultivars i.e., H10 (Anaswara x PKB 3) and H11 (Anaswara x PKB 4). The crosses were evaluated in the Department of Plant Breeding and Genetics, Kerala Agricultural University, Thrissur during cowpea season 2015-2017. Trait association based on correlation and path analysis was carried out with phenotypic data from F2 and F3 generations of the crosses. Result: In F2 generation of cross H10, number of pods per plant and number of seeds per pod displayed significant positive correlation with seed yield per plant. In F3 generation of cross H10, number of pods per plant and 100-seed weight per plant exhibited significant positive correlation with seed yield per plant. In cross H11, number of pods, pod length, single pod weight, number of seeds per pod and 100-seed weight revealed significant1 positive correlation with yield in segregating generations. On path analysis, various quantitative characters showed positive direct effects on seed yield. Selection of segregants based on the yield contributing characters is likely to be desirable for yield improvement in cowpea.
Metatranscriptomic Approach to Understand the Role of the Rhizosphere Microbiome: A Review
Authors: Kumari Naina , . Uma , Iquebal M.A. , Jaiswal Sarika , Rai Anil , Kumar Dinesh
Published: August 2022

Plant roots harbour diverse microorganisms that interact with each other and the plants. Rhizosphere is the region of soil, closely associated with plant root. The microbiome associated with them is termed as rhizobiome. Its studies give insights into the roles of the microorganisms in plant health. With the advancement of NGS techniques, the identification of the non-cultural species has turned out to be possible. Sequencing of the whole genomic D.N.A. (metagenomics) can easily identify the taxonomic and functional profile but identification of the active and inactive members of the microbiome is not fulfilled. Meta-transcriptomics helps in determining the active functional profile of a microbial community by identifying the genes expressed by the entire microbial community. The general workflow is sampling, RNA extraction, library preparation, sequencing, pre-processing of data, assembly, taxonomic/functional profiling and the differential expression analysis. There exist numerous challenges, that can be overcome through enhanced sequencing technologies and algorithms.
Influence of Acupuncture on Expression of Mitochondrial Fusion and Fission Mediators in Rat Liver
Authors: Lee Yu-Mi , Choi Dong-Hee , Cheon Min-Woo , Kim Jae Gwan , Kim Jeong Sang , Kim Hye-Ran , Youn Daehwan
Published: August 2022

Background: We aimed to elucidate the mechanism of change in mitochondrial fusion- and fission-related mediators for maintaining cell function through the effects of acupuncture treatment and apply findings to a liver disease model. We focused on the optic atrophy-1 (OPA1) and fission protein 1 (Fis1) genes of rat liver cells. Methods: Sprague Dawley rats were divided into a control group (no treatment) and LR2, LR3, LR4 and LR8 groups (acupuncture treatment to those points). Acupuncture was performed on each point for 10 minutes once daily for 4 days. Changes in the mRNA expression of Peroxisome proliferator-activated receptor-gamma coactivator 1-α (PGC-1α) and Fis1 were observed via quantitative real-time polymerase chain reaction (qRT-PCR); changes in OPA1, mitofusin-2 (MFN2), mitofusin-1 (MFN1), dynamin-related protein 1 (DRP1) and adenosine monophosphate-activated protein kinase (AMPK) proteins were observed through western blotting and endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) expressions were observed through immunohistochemistry. Result: OPA1 decreased in the LR3 and LR8 groups and Fis1 increased in the LR2 and LR4 groups. AMPK and PGC-1α decreased significantly in all acupuncture groups. eNOS and nNOS expression reduced in all acupuncture groups. Therefore, acupuncture can regulate mitochondrial fusion/fission by influencing the following mediators: AMPK, PGC-1α, OPA1, Fis1, eNOS and nNOS.
Studies on Distribution of Sugarcane Yellow Leaf Virus in Commercially Grown Sugarcane Varieties in Andhra Pradesh
Authors: Hemalatha T.M. , Reddy B.V. Bhaskara , Jayalakshmi R. Sarada , Rao S.R. Koteswara , Kumar M. Hemanth , Naidu G. Mohan
Published: August 2022

Background: Among the diseases of sugarcane, Sugarcane yellow leaf disease (YLD) is one of the most prevalent diseases of sugarcane posing serious threat to the sugarcane cultivation worldwide. The current study aims at studying the distribution of SCYLV in the major sugarcane-growing of Andhra Pradesh and determining sequence identities, sequence variations and phylogenetic relationships between the SCYLV isolates reported earlier from India and worldwide. Methods: ORF1 and ORF2 regions of the viral genome coding for RNA dependent RNA Polymerase (RdRP) was amplified from twelve of the samples using the gene specific primers viz., SCYLV-F3 and SCYLV-R3. The ORF1 and ORF2 regions were studied for sequence similarity at nucleotide and aminoacid level and phylogentic relationships were established with the other SCYLV isolates. Result: The multiple sequence analysis of the isolates under the study with 22 similar sequences of SYLCV isolates reported from India and worldwide revealed 90.6-100% identities with IND, REU, BRA, CHN, HAW, CUB, COL and PER genotypes reported worldwide. The Indian isolates showed close phylogenetic relationship with the CUB and COL isolates. Hence it was confirmed from the study that SCYLV isolates collected from major sugarcane growing regions of Andhra Pradesh closely related to SCYLV-CUB and SCYLV-COL genotypes.
Efficient Propagation Methods and Management Implication of Aconitum chasmanthum Stapf ex Holmes: A Critically Endangered and Endemic Medicinal Herb of Kashmir Himalaya
Authors: Mohi-Ud-Din G.G. , Nawchoo Irshad A. , Wafai B.A.
Published: August 2022

Background: Knowledge about propagation of rare and endangered plant species is very important for their conservation and sustainable utilization. Therefore, it is imperative to understand different reproductive aspects of such species for their conservation and management. It is in this backdrop different propagation method of Aconitum chasmanthum- a Critically Endangered and Endemic Medicinal plant species has been undertaken. Methods: Seed germination was carried out using different media. For each treatment mean germination time (MGT) was also calculated. Different agro-techniques were also developed in different soil textural classes. The fresh underground tubers of the species were collected from natural population and were split longitudinally into 2, 3 and 4 pieces depending upon the size of the parental tuber containing a portion of shoot apex. The split cuttings were treated with 100 ppm IAA, IBA and GA3 for 48 hours and were sown in sandy loam soils under pots at Herbal Garden. The pots were kept in diffused light to monitor the leafy shoot generation, survival and comparison with the control (untreated cuttings). Result: The present study revealed that seeds of the species remain dormant for a pretty long period and do not germinate in darker conditions. Among various treatments the species showed 90.0±8.66% germination when chilled for 20 days with mean germination time (MGT) of 13.678±1.874 days as against 10.66±1.154% germination of the control. Although the plants grew nicely on various soils, maximum plant survival and vigorous growth was obtained in loamy textured soils. The plants responded to various nutrient treatments and in loamy soil the maximum dry biomass was shown by the plants treated with nitrogen (300 mg/kg soil) and NPK (500 mg/kg soil). The plants treated with NPK (500 mg/kg soil) produced 14.46±2.50 gm dry biomass as against the control of 5.23±0.750 gm per individual. The experimental manipulations also reveal that the species has a potential to propagate through tuber cuttings in sandy loam soils. The cuttings treated with IAA, IBA and GA3 showed 68.75% to 75.0% survival rate as against the 62.5% in control.
​​Potential of Vermiwash Prepared from Different Combinations of Organic Wastes to Improve the Growth, Yield and Quality of Organic Black Gram
Authors: Kumar Deepak , Sharma S.K. , Kumar Brijesh , Kumar Sandeep , Kashyap Suryakanta , Kumar Rakesh
Published: August 2022

Background: Excessive and unbalanced chemical fertilization in crop husbandry has attracted much attention because of soil health issues, reducing crop quality, increasing production cost and environmental risks. Organic farming is perceived as the best-known alternative method and has numerous environmental benefits. “Vermiwash” is liquid manure extracted from earthworms rich-vermicompost containing soluble nutrients, growth hormones, enzymes and many micro-organisms. As a result, the purpose of this study was to see how vermiwash affected the production and quality of black gram. Methods: During the kharif 2018, a field experiment was set up in a randomized block design to assess the effect of nine vermiwash treatments prepared from different organic wastes like cow dung, buffalo dung, green and dry field wastes and their combinations on growth, yield attributes and yield, nutrients and protein content of organic black gram (var. PU-31) and biochemical properties of vermiwash. Result: The neutral to slightly alkaline pH (7.72), E.C. (1.39 dSm-1) and maximum nutrients content, greatest average microbiological count (total number of bacteria, fungi and actinomycetes) and enzyme activity (acid phosphatase, alkaline phosphatase and dehydrogenase) were significantly found in treatment (T1) among the various vermiwash treatments at 35 days after collection. Moreover, the foliar application of vermiwash treatment (T1) significantly recorded highest growth, seed yield, nutrients and protein content. Based on-field results, it is possible to infer that treatment T1 (foliar spray in two equal split applications at a rate of 10% at the onset of flowering and 15 days following the first spray) is a better fertilizer practice for organic black gram cultivation.
L’Usage Du Texte Littéraire Comme Support Authentique Dans L’Enseignement Du FLE: Exemple d’Archipel
Authors: ATAN Nurhayat
Published: August 2022

Le texte littéraire avait été longtemps utilisé avant et au début du XXe siècle comme instrument didactique dans le développement des compétences de l’apprenant en formation de langue étrangère et délaissé pourtant jusqu’aux méthodologies communicatives. L’objectif de cette recherche est d’examiner et de révéler son remaniement comme support authentique, dans le manuel de français «Archipel», paru au début des années 80, fondé sur l’approche communicative. Pour ce faire, les trois livres du manuel ont été analysés d’une manière comparative afin de mettre en évidence et en discussion la fréquence d'utilisation des textes, la diversité des genres littéraires et les caractéristiques géographiques et temporelles des auteurs sélectionnés par les concepteurs de l'ouvrage. Notre recherche se veut une étude descriptive qui sera réalisée par la méthode d'analyse de documents. Les données ont été obtenues par analyse de contenu. Selon les résultats obtenus à l’issu de cette recherche, bien que le manuel présente certaines lacunes en termes d'activités pédagogiques associées aux textes littéraires, il pourrait être considéré comme un support pédagogique idéal et pertinent pour véhiculer la culture cible du fait qu’il offre progressivement une riche variété de textes en nombre croissant en termes de matériel, soigneusement sélectionné, compte tenu de la langue et niveau d'éducation du public cible.
PSYCHOMETRIC EVALUATION OF A QUESTIONNAIRE FOR MEASURING FOOD WASTE BEHAVIOUR AND FOOD SECURITY AT THE HOUSEHOLD LEVEL
Authors: Tung Wong Liang , Rahman Md Mizanur
Published: August 2022

Introduction: Food waste and food security are two concepts that are often linked together. This study was performed for the psychometric evaluation of a developed questionnaire for measuring food waste behaviour and food security at the household level. Five expert panels conducted content validation for the relevance, clarity, simplicity, ambiguity of each item. Methods: A cross-sectional quantitative research approach was employed for the questionnaire testing in 10 villages in the Samarahan district of Sarawak state. A total of 168 households were interviewed using face-to-face interviews. Data entry and analysis was undertaken using Microsoft Excel version 2016 and the statistical package for social sciences (SPSS, version 27.0), Result: respectively. Four items were improved, and one item was added to the English questionnaire after receiving feedback from the expert panel and respondents. Further refinement was also performed for the Malay version. Cronbach's alpha value varied from 0.713 to 0.961, indicating the reliability of the questionnaire. Conclusion: Overall, the respondents were able to comprehend most of the questions effectively. No problem was raised for the flow and sequence of the questions. Conclusively, the developed questionnaire is unambiguous in its reliability and validity. Nevertheless, further refinement is required before being used in future studies.