bluuebunny/crossref_metadata_2025 huggingface dataset:
The Optimal Reform About Property Tax
Authors: Yamazaki Fukuju
Published: February 2021

We present the desirable tax reform on the property tax on land and housing in Japan. Since the property tax on housing, building, and equipment becomes an obstacle to the capital formation on land, it should be abolished. Conversely, the effective rate of property tax on land should be increased so as to attain the revenue neutrality for local government. The abolition of tax on housing induces the higher land price which can bear the increase in the property tax on land, so that such a tax reform would benefit all individuals.
Requirements for the Application of Exemption from Real Estate Acquisition Tax Due to Purpose of Use: Based on the Acquisition of Land Usage for a School Site by an Incorporated Educational Institution
Authors: Kobayashi Nobuyuki
Published: February 2021

When an incorporated educational institution acquires real estate to establish a school, real estate acquisition tax is tax exemption. There are two interpretations of these tax exemption requirements: interpreting that real estate acquisition to establish a school is a requirement for tax exemption and interpreting that the establishment of a school is a requirement for tax exemption requirement. This paper discusses these tax exemption requirements, along with their accreditation standards and limited interpretation.
Factor Analysis of Rent Using Space Syntax Measures: Comparative Analysis by Building Use around Shibuya Station
Authors: Ota Akira , Takahashi Hiroshi , Kaneda Toshiyuki
Published: February 2021

The determinants of residential, office and commercial rent are each analyzed by taking the 10 min walking distance area around Shibuya Station in Tokyo as the research target area. Conventional physical and quantitative factors such as distance from the nearest station, the width of the frontal road, age of the building, the number of floors, total floor area, contracted floor area, building structure etc. are included in the multiple-regression analysis as well as qualitative factors such as the visible area representing visibility on a main street and the integration value representing street network centrality—easy accessibility from other locations such as any intersection points—based on the space syntax measures (SS measures) used in the analysis by Jake Desyllas from University College of London. It is shown that both SS measures affect the rent for all the residential, office and commercial uses with the statistically significant level of 5%. It is quantitatively confirmed that the residential rent increases in a secluded location, and the office and commercial rent rise in a location with high street network centrality and good access, which would suggest that the SS measures are crucial important rent factors for residential, offices, and commercial uses in other places in Japan.
Compact City Corresponding to the Advanced Transport Systems
Authors: Morimoto Akinori
Published: February 2021

Location normalization plans that are currently being established across the country encourage a loose approach to land utilization guidance by establishing the areas where urban function guidance and residential guidance apply. We will consider some hints as to how to proceed with urban downsizing by looking back at how urban areas expanded during the period of population growth. It is important that the characteristics and roles of each transport system are reorganized and that they are skillfully incorporated into cities. In particular, the formation of transfer points between main line transport systems and branch line transport systems is a key to the formation of compact cities.
Current Status and Issues for Urban (Regional Area) Formulation of the Location Normalization Plan: The Case of Niigata City
Authors: Ogushi Yoko
Published: February 2021

In the case that the amount of investment differs between the designated area and other area, the impact on land prices will be unavoidable. In Niigata City, the plan has just been completed. From now on, we need to pay close attention to how to make land use more appropriate by policy guidance and how it affects the land price.
The Overview and Legal Issues Regarding Real Estate Tech
Authors: Narimoto Haruo
Published: February 2021

In this paper, I will introduce the types of real estate tech services already provided in Japan and give concrete examples, as well as explain the real estate crowdfunding, which is attracting particular attention, including laws and regulations. I will also discuss the legal issues in the use of data and personal information that are expected to arise in real estate tech services in the future.
Empirical Analysis on the System Revisions of Judicial Real Estate Auctions: Comparison with General Real Estate Trading
Authors: Ooka Yusuke
Published: February 2021

This paper shows the effect of a series of system revisions of judicial real estate auction in the 2000s on three factors: bid acceptance ratio, number of bidders, and highest bid. Using multiyear data of auctions from multiple district courts, I estimate the improvement of the three factors by the revision.

Furthermore, comparing real estate auction data with voluntary sale and general real estate trading data, I find that the selling price in auction was greatly lower than the price in voluntary sale even after the system revisions. Based on the empirical results, I suggest about necessity of further system revisions.
Bra-ket wormholes in gravitationally prepared states
Authors: Chen Yiming , Gorbenko Victor , Maldacena Juan
Published: February 2021

Abstract

We consider two dimensional CFT states that are produced by a gravitational path integral.

As a first case, we consider a state produced by Euclidean AdS2 evolution followed by flat space evolution. We use the fine grained entropy formula to explore the nature of the state. We find that the naive hyperbolic space geometry leads to a paradox. This is solved if we include a geometry that connects the bra with the ket, a bra-ket wormhole. The semiclassical Lorentzian interpretation leads to CFT state entangled with an expanding and collapsing Friedmann cosmology.

As a second case, we consider a state produced by Lorentzian dS2 evolution, again followed by flat space evolution. The most naive geometry also leads to a similar paradox. We explore several possible bra-ket wormholes. The most obvious one leads to a badly divergent temperature. The most promising one also leads to a divergent temperature but by making a projection onto low energy states we find that it has features that look similar to the previous Euclidean case. In particular, the maximum entropy of an interval in the future is set by the de Sitter entropy.
Is ink heating a relevant concern in the High Speed Sintering process?
Authors: Williams Rhys J. , Smith Patrick J. , Majewski Candice
Published: February 2021

High Speed Sintering (HSS) is a novel polymer additive manufacturing process which utilises inkjet printing of an infrared-absorbing pigment onto a heated polymer powder bed to create 2D cross-sections which can be selectively sintered using an infrared lamp. Understanding and improving the accuracy and repeatability of part manufacture by HSS are important, ongoing areas of research. In particular, the role of the ink is poorly understood; the inks typically used in HSS have not been optimised for it, and it is unknown whether they perform in a consistent manner in the process. Notably, the ambient temperature inside a HSS machine increases as a side effect of the sintering process, and the unintentional heating to which the ink is exposed is expected to cause changes in its fluid properties. However, neither the extent of ink heating during the HSS process nor the subsequent changes in its fluid properties have ever been investigated. Such investigation is important, since significant changes in ink properties at different temperatures would be expected to lead to inconsistent printing and subsequently variations in part accuracy and even the degree of sintering during a single build. For the first time, we have quantified the ink temperature rise caused by unintentional, ambient heating during the HSS process, and subsequently measured several of the ink’s fluid properties across the ink temperature range which is expected to be encountered in normal machine operation (25 to 45 ∘C). We observed only small changes in the ink’s density and surface tension due to this heating, but a significant drop (36%) in its viscosity was seen. By inspection of the ink’s Z number throughout printing, it is concluded that these changes would not be expected to change the manner in which droplets are delivered to the powder bed surface. In contrast, the viscosity decrease during printing is such that it is expected that the printed droplet sizes do change in a single build, which may indeed be a cause for concern with regard to the accuracy and repeatability of the inkjet printing used in HSS, and subsequently to the properties of the polymer parts obtained from the process.
Sternocleidohyoid muscle: an unreported variant of cleidohyoid muscle
Authors: Nayak Satheesha B. , Shetty Surekha D.
Published: February 2021

Sternohyoid, sternothyroid, omohyoid, and thyrohyoid muscles are collectively known as infrahyoid muscles. These muscles frequently show variations in their attachments. Here, an extremely rare variant muscle belonging to this group has been presented. During cadaveric dissection for undergraduate medical students, an additional muscle was found between sternohyoid and superior belly of omohyoid muscles bilaterally in a male cadaver aged approximately 70 years. This muscle took its origin from posterior surface of the manubrium sterni, capsule of the sternoclavicular joint and the posterior surface of the medial part of the clavicle. It was inserted to the hyoid bone between the attachments of sternohyoid and superior belly of omohyoid muscles and was supplied by a branch of ansa cervicalis profunda. There is no report on such a muscle in the literature and it could be named as “sternocleidohyoid muscle”. Knowledge of this muscle could be useful in neck surgeries.
Anaesthesia as an influence in tumour progression
Authors: Plücker Jadie , Wirsik Naita M. , Ritter Alina S. , Schmidt Thomas , Weigand Markus A.
Published: February 2021

Purpose

Tumour growth and the formation of metastases are essential elements in the progression of cancer. The centre of treatment is the surgical resection of primary solid tumours. But even if the tumour can be removed without microscopic residual cells, local recurrences and distant metastases occur and determine the patient’s fate. During the operation, tumour cells are shed from the primary tumour and released into the circulation. These circulating tumour cells might play an important role in the formation of new tumour sites. Therefore, a functional innate and adaptive immune system is essential, especially in this perioperative period. Anaesthesia influences consciousness and pain perception and interacts directly with the immune system and tumour cells.

Methods

Review of the current literature concerning intra- and postoperative anaesthetic decisions and tumour progression.

Results

There are beneficial aspects for patient survival associated with total intravenous anaesthesia, the use of regional anaesthetics and the avoidance of allogeneic red blood cell transfusions. Alternatives such as irradiated intraoperative blood salvage and preoperative iron supplementation may be advantageous in cases where transfusions are limited or not wanted. The immunosuppressive properties of opioids are theoretical, but strong evidence to avoid them does not exist. The application of nonsteroidal anti-inflammatory drugs and postoperative nausea and vomiting prophylaxis do not impair the patient’s survival and may even have a positive effect on tumour regression.

Conclusion

Anaesthesia does play an important part in the perioperative period in order to improve the cancer-related outcome. Further research is necessary to make more concrete recommendations.
ISSLS prize in basic science 2021: a novel inducible system to regulate transgene expression of TIMP1
Authors: Han Yingchao , Ouyang Zhihua , Wawrose Richard A. , Chen Stephen R. , Hallbaum Maximiliane , Dong Qing , Dando Emily , Tang Ying , Wang Bing , Lee Joon Y. , Shaw Jeremy D. , Kang James D. , Sowa Gwendolyn A. , Vo Nam N.
Published: February 2021

Purpose

Inflammatory and oxidative stress upregulates matrix metalloproteinase (MMP) activity, leading to intervertebral disc degeneration (IDD). Gene therapy using human tissue inhibitor of metalloproteinase 1 (hTIMP1) has effectively treated IDD in animal models. However, persistent unregulated transgene expression may have negative side effects. We developed a recombinant adeno-associated viral (AAV) gene vector, AAV-NFκB-hTIMP1, that only expresses the hTIMP1 transgene under conditions of stress.

Methods

Rabbit disc cells were transfected or transduced with AAV-CMV-hTIMP1, which constitutively expresses hTIMP1, or AAV-NFκB-hTIMP1. Disc cells were selectively treated with IL-1β. NFκB activation was verified by nuclear translocation. hTIMP1 mRNA and protein expression were measured by RT-PCR and ELISA, respectively. MMP activity was measured by following cleavage of a fluorogenic substrate.

Results

IL-1β stimulation activated NFκB demonstrating that IL-1β was a surrogate for inflammatory stress. Stimulating AAV-NFκB-hTIMP1 cells with IL-1β increased hTIMP1 expression compared to unstimulated cells. AAV-CMV-hTIMP1 cells demonstrated high levels of hTIMP1 expression regardless of IL-1β stimulation. hTIMP1 expression was comparable between IL-1β stimulated AAV-NFκB-hTIMP1 cells and AAV-CMV-hTIMP1 cells. MMP activity was decreased in AAV-NFκB-hTIMP1 cells compared to baseline levels or cells exposed to IL-1β.

Conclusion

AAV-NFκB-hTIMP1 is a novel inducible transgene delivery system. NFκB regulatory elements ensure that hTIMP1 expression occurs only with inflammation, which is central to IDD development. Unlike previous inducible systems, the AAV-NFκB-hTIMP1 construct is dependent on endogenous factors, which minimizes potential side effects caused by constitutive transgene overexpression. It also prevents the unnecessary production of transgene products in cells that do not require therapy.
The effect of seaweed extract on tomato plant growth, productivity and soil
Authors: Hussain Hashmath Inayath , Kasinadhuni Naga , Arioli Tony
Published: February 2021

This study investigated the effects of seaweed extract (SWE) made from the brown algaeDurvillaea potatorumandAscophyllum nodosumon plants and soil. The application of SWE to soil growing tomato plants showed dual effects. SWE comprehensively improved tomato plant growth (flower clusters, flower number, fruit number, root length, root and shoot dry weight, SPAD) and increased plant productivity (yield and quality). Similarly, SWE application effected soil biology at the soil root zone by increasing total bacterial count and available soil nitrogen and impacting bacterial community diversity with an increase in certain bacterial families linked to soil health. A broader understanding of the effects of SWE on the plant-soil ecosystem may offer breakthrough approaches for sustainable food production.
The decomposition process in high-purity Al-1.7 at.% Cu alloys with trace elements: preservation of quenched-in vacancies by In, Sn and Pb influencing the $$\theta \, '$$ formation
Authors: Staab Torsten E. M. , Lotter Frank , Mühle Uwe , Elsayed Mohamed , Petschke Danny , Schubert Thomas , Ibrahim Alaa M. , Krause-Rehberg Reinhard , Kieback Bernd
Published: February 2021

Aluminium-copper alloys of the 2xxx type receive their excellent mechanical properties by the formation of copper-rich precipitates during hardening. Size, distribution and crystal structure of the formed precipitates determine the final strength of those alloys. Adding traces of certain elements, which bind to vacancies, significantly influences the decomposition behaviour, i.e. the diffusion of the copper atoms. For high-purity ternary alloys (Al-1.7 at.% Cu-X), we investigate the interaction of copper and trace element atoms (X=In, Sn, and Pb) with quenched-in vacancies by Positron Annihilation Lifetime Spectroscopy (PALS). By employing Vickers microhardness, Differential Scanning Calorimetry (DSC) and Small Angle X-Ray Scattering (SAXS) we obtain a comprehensive picture of the decomposition process: opposite to predicted binding energies to vacancies by ab-initio calculations we find during ageing at room and elevated temperature a more retarded clustering of copper in the presence of In rather than for Sn additions, while Pb, having the highest predicted binding to vacancies, shows nearly no retarding effect compared to pure Al-Cu. If the latter would be due to a limited solubility of lead, it had to be below 2 ppm. Transmission Electron Microscopy (TEM) as imaging method complements our findings. Annealing the quenched Al-1.7 at.% Cu-X-alloys containing 100 ppm In or Sn at$$150\,^\circ {\text {C}}$$150∘Cleads to finely distributed$$\theta \, '$$θ′-precipitates on the nanoscale, since due to the trace additions the formation temperature of$$\theta \, '$$θ′is lowered by more than$$100\,^\circ {\text {C}}$$100∘C. According to TEM small agglomerates of trace elements (In, Sn) may support the early nucleation for the$$\theta \, '$$θ′-precipitates.
Mechanisms contributing to hypotension after anesthetic induction with sufentanil, propofol, and rocuronium: a prospective observational study
Authors: Saugel Bernd , Bebert Elisa-Johanna , Briesenick Luisa , Hoppe Phillip , Greiwe Gillis , Yang Dongsheng , Ma Chao , Mascha Edward J. , Sessler Daniel I. , Rogge Dorothea E.
Published: February 2021

It remains unclear whether reduced myocardial contractility, venous dilation with decreased venous return, or arterial dilation with reduced systemic vascular resistance contribute most to hypotension after induction of general anesthesia. We sought to assess the relative contribution of various hemodynamic mechanisms to hypotension after induction of general anesthesia with sufentanil, propofol, and rocuronium. In this prospective observational study, we continuously recorded hemodynamic variables during anesthetic induction using a finger-cuff method in 92 non-cardiac surgery patients. After sufentanil administration, there was no clinically important change in arterial pressure, but heart rate increased from baseline by 11 (99.89% confidence interval: 7 to 16) bpm (P < 0.001). After administration of propofol, mean arterial pressure decreased by 23 (17 to 28) mmHg and systemic vascular resistance index decreased by 565 (419 to 712) dyn*s*cm−5*m2 (P values < 0.001). Mean arterial pressure was < 65 mmHg in 27 patients (29%). After propofol administration, heart rate returned to baseline, and stroke volume index and cardiac index remained stable. After tracheal intubation, there were no clinically important differences compared to baseline in heart rate, stroke volume index, and cardiac index, but arterial pressure and systemic vascular resistance index remained markedly decreased. Anesthetic induction with sufentanil, propofol, and rocuronium reduced arterial pressure and systemic vascular resistance index. Heart rate, stroke volume index, and cardiac index remained stable. Post-induction hypotension therefore appears to result from arterial dilation with reduced systemic vascular resistance rather than venous dilation or reduced myocardial contractility.
Poncelet property and quasi-periodicity of the integrable Boltzmann system
Authors: Felder Giovanni
Published: February 2021

We study the motion of a particle in a plane subject to an attractive central force with inverse-square law on one side of a wall at which it is reflected elastically. This model is a special case of a class of systems considered by Boltzmann which was recently shown by Gallavotti and Jauslin to admit a second integral of motion additionally to the energy. By recording the subsequent positions and momenta of the particle as it hits the wall, we obtain a three-dimensional discrete-time dynamical system. We show that this system has the Poncelet property: If for given generic values of the integrals one orbit is periodic, then all orbits for these values are periodic and have the same period. The reason for this is the same as in the case of the Poncelet theorem: The generic level set of the integrals of motion is an elliptic curve, and the Poincaré map is the composition of two involutions with fixed points and is thus the translation by a fixed element. Another consequence of our result is the proof of a conjecture of Gallavotti and Jauslin on the quasi-periodicity of the integrable Boltzmann system, implying the applicability of KAM perturbation theory to the Boltzmann system with weak centrifugal force.
Convergence properties of the Broyden-like method for mixed linear–nonlinear systems of equations
Authors: Mannel Florian
Published: February 2021

We consider the Broyden-like method for a nonlinear mapping$F:\mathbb {R}^{n}\rightarrow \mathbb {R}^{n}$F:ℝn→ℝnthat has some affine component functions, using an initial matrixB0that agrees with the Jacobian ofFin the rows that correspond to affine components ofF. We show that in this setting, the iterates belong to an affine subspace and can be viewed as outcome of the Broyden-like method applied to a lower-dimensional mapping$G:\mathbb {R}^{d}\rightarrow \mathbb {R}^{d}$G:ℝd→ℝd, wheredis the dimension of the affine subspace. We use this subspace property to make some small contributions to the decades-old question of whether the Broyden-like matrices converge: First, we observe that the only available result concerning this question cannot be applied if the iterates belong to a subspace because the required uniform linear independence does not hold. By generalizing the notion of uniform linear independence to subspaces, we can extend the available result to this setting. Second, we infer from the extended result that if at most one component ofFis nonlinear while the others are affine and the associatedn− 1 rows of the Jacobian ofFagree with those ofB0, then the Broyden-like matrices converge if the iterates converge; this holds whether the Jacobian at the root is invertible or not. In particular, this is the first time that convergence of the Broyden-like matrices is proven forn> 1, albeit for a special case only. Third, under the additional assumption that the Broyden-like method turns into Broyden’s method after a finite number of iterations, we prove that the convergence order of iterates and matrix updates is bounded from below by$\frac {\sqrt {5}+1}{2}$5+12if the Jacobian at the root is invertible. If the nonlinear component ofFis actually affine, we show finite convergence. We provide high-precision numerical experiments to confirm the results.
The Development of a Multilevel Intervention to Optimise Participant Engagement with an Obesity Prevention Programme Delivered in UK children’s Centres
Authors: Burton Wendy , Sahota Pinki , Twiddy Maureen , Brown Julia , Bryant Maria
Published: February 2021

Poor participant engagement threatens the potential impact and cost-effectiveness of public health programmes preventing meaningful evaluation and wider application. Although barriers and levers to engagement with public health programmes are well documented, there is a lack of proven strategies in the literature addressing these. This paper details the development of a participant engagement intervention aimed at promoting enrolment and attendance to a community-based pre-school obesity prevention programme delivered in UK children’s centres; HENRY (Health, Exercise, Nutrition for the Really Young). The Behaviour Change Wheel framework was used to guide the development of the intervention. The findings of a coinciding focused ethnography study identified barriers and levers to engagement with HENRY that informed which behaviours should be targeted within the intervention to promote engagement. A COM-B behavioural analysis was undertaken to identify whether capability, opportunity or motivation would need to be influenced for the target behaviours to occur. APEASE criteria were used to agree on appropriate intervention functions and behaviour change techniques. A multi-level participant engagement intervention was developed to promote adoption of target behaviours that were proposed to promote engagement with HENRY, e.g. ensuring the programme is accurately portrayed when approaching individuals to attend and providing ‘taster’ sessions prior to each programme. At the local authority level, the intervention aimed to increase buy-in with HENRY to increase the level of resource dedicated to engagement efforts. At the centre level, managers were encouraged to widen promotion of the programme and ensure that staff promoted the programme accurately. HENRY facilitators received training to increase engagement during sessions, and parents that had attended HENRY were encouraged to recruit their peers. This paper describes one of the first attempts to develop a theory-based multi-level participant engagement intervention specifically designed to promote recruitment and retention to a community-based obesity prevention programme. Given the challenges to implementing public health programmes with sufficient reach, the process used to develop the intervention serves as an example of how programmes that are already widely commissioned could be optimised to enable greater impact.
Der Eisenstoffwechsel und seine Bedeutung für das Höhentraining
Authors: Neumann Georg , Hottenrott Kuno , Hottenrott Laura
Published: February 2021

Ein Eisenmangel und eine katabole Stoffwechsellage behindern die Zunahme des Gesamthämoglobins und damit einen Anstieg der Sauerstofftransportkapazität, sodass die Wirksamkeit des Höhentrainings herabgesetzt ist. Die Eisenhomöostase wird sehr fein durch das hepatische Hormon Hepcidin (HEPC) kontrolliert, welches die Eisenaufnahmefähigkeit der Darmzellen über ein spezielles Protein, dem Ferroportin, kontrolliert. Unter Hypoxie stimuliert das Protein HIF-1 α die Freisetzung des Erythropoitins (EPO). Unzureichende Eisenspeicher und/oder eine Vitamin-B12-Unterversorgung bei Athleten, besonders bei jungen Frauen, sind Wochen vor einem Höhentraining durch eine orale Eisen- und/oder Vitamin-B12-Substitution unter ärztlicher Kontrolle, aufzufüllen. Voraussetzung für eine leistungsfördernde Wirkung des Höhentrainings ist ein mehrmaliger Aufenthalt in mittleren Höhen von 1700 m bis 3000 m. Als Aufenthaltsdauer werden 350 h bis 500 h oder zwei bis drei Wochen empfohlen. Mangelnde Eisenverfügbarkeit und ein Energiedefizit können die Wirksamkeit des Höhentrainings negativ beeinflussen. Liegt aus medizinischer Sicht eine Eisenunterversorgung vor, dann wird zu einer oralen Supplementation vor und während des Höhentrainings geraten. Bei normaler Eisenverfügbarkeit führt die gesteigerte Hämatopoese durch EPO zur Zunahme des Gesamthämoglobins. Die Wirkung des hypoxieinduzierten Hämoglobinanstiegs ist nach dem Höhentraining auf drei bis vier Wochen begrenzt.
The Summer School Oncology Groningen: Improving a Successful International Course by Refining the Old, Maintaining What’s Good
Authors: Boske E. C. E. , Nienhuis P. H. , Hammer C. , Jalving M. , Kruyt F. A. E. , de Vries J. , Roodenburg J. L. N. , Metman M. J. H. , Kruijff S.
Published: February 2021

For more than two decades, the International Summer School Oncology for Medical Students (ISOMS) has organized a biennial 2-week international summer school program in Groningen, the Netherlands. The summer school aims to increase knowledge about general cancer care, reduce fear of talking to cancer patients, and expose students to cancer-related problems. After 22 years, there was a need to improve the summer school format, the application procedure, and the intensity of the course. Here, we describe and evaluate these and additional changes that were made to the program. Several changes were made to the summer school format. The course was shortened from 10 days to a more intensive 7 days. The scientific program was integrated with the clinical program and students were taught scientific writing and presentation skills. The application process involved a personal video pitch. Importantly, the new summer school format was organized by a committee in which medical students had the lead. To evaluate the changes to the summer school, we conducted knowledge tests and regularly obtained feedback. There was a high overall student satisfaction, with a median score of a 9 out of 10. Students appreciated the interactive sessions and practicals and the scientific program, and were satisfied with the course level. All students had improved test scores. Improvement points highlighted the need for a less packed schedule and more lectures on basic oncology principles, or were related to specific lectures. The student-led innovation and adaptation of the ISOMS has been successful.
Does Religion Affect Perception of Pregnancy Timing among Women Using Contraception?
Authors: Langley Rachael , Bably Morium , Siebens Ryan , Diaz Maria , Brunner Huber Larissa
Published: February 2021

Background

Nearly half of all pregnancies in the U.S. are unintended. Unintended pregnancy refers to a mistimed or unwanted pregnancy. Unwanted and mistimed pregnancies are often distinguished from each other because of the negative social connotations and poorer health outcomes associated with unwanted pregnancies. However, mistimed pregnancies also pose significant economic, societal, and health burdens that necessitate enhanced risk factor identification and prevention efforts.

Purpose

Religion and religious practices are important to consider as potential risk factors for mistimed pregnancy as over 70% of Americans identify as religious. However, little research exists on the potential religious factors-mistimed pregnancy association. The purpose of this study was to evaluate this association among women using contraception in the U.S.

Methods

This analysis used National Survey of Family Growth data. Women (n = 2841) self-reported measures of religion, religiosity and pregnancy timing. Logistic regression was used to obtain odds ratios (ORs) and 95% confidence intervals.

Results

After adjustment, women who reported currently being Catholic, Protestant, or another religion had statistically significant increased odds of mistimed pregnancy compared to women with no current religious affiliation (Catholic OR = 2.31, Protestant OR = 1.41, Other OR = 2.58). Women who reported that religion was very important or somewhat important had statistically significant increased odds of mistimed pregnancy (Very Important OR = 1.82, Somewhat Important OR = 1.60). More frequent service attendance was associated with statistically significant decreased odds of mistimed pregnancy. Specifically, women who reported attending services 2–3 times a month or 1 or more times per week had nearly half the odds of mistimed pregnancy compared to women who never attended services (OR = 0.54 and OR = 0.51).

Conclusions and Implications

This study provides insight into the interrelationship of religion as a sociocultural risk factor for mistimed pregnancy and found that while religiously active women had increased odds of mistimed pregnancy, frequency of service attendance was a protective factor against mistimed pregnancy. Given that approximately half of pregnancies in the U.S. are unintended, additional studies are needed to further understand cultural mechanisms that may be important risk factors of unintended pregnancy, and to confirm this study's findings.
Performance of flow and heat transfer analysis of mixed convection in Casson fluid filled lid driven cavity including solid obstacle with magnetic impact
Authors: Ali Mohammad Mokaddes , Akhter Rowsanara , Alim M. A.
Published: February 2021

In this study, the heat transfer and fluid flow characteristics of mixed convection in a double lid driven cavity containing a heat conducting solid obstacle in presence of magnetic field is numerically investigated. The left and right vertical walls of the cavity are isothermally heated and cooled respectively while horizontal walls are thermally insulated. A solid cylinder is positioned at the centre of the cavity. Mathematical model has been developed considering non-Newtonian model of Casson fluid and solved with finite element method based on Galerkin residual technique. The simulated numerical results are obtained through streamlines, temperature contours and average Nusselt number for a set of dimensionless parameters and discussed elaborately to make the effective usability of Casson fluid in different industrial and engineering processes. The obtained results based on special cases are compared with the existing results. It is observed that the flow and thermal fields were influenced significantly by the Reynolds number for any Casson fluid parameter. The intensification of streamlines strengthened for Casson fluid parameter compared to isotherms. Moreover, enhancement of heat transfer due to increased Reynolds number expedites with Casson fluid parameter while a reverse trend is observed for higher Hartmann number. In addition, appropriate direction of lid walls provides a better heat transfer rate.
Sustainability of a program to reduce unnecessary urethral catheter use at a Veterans Affairs hospital
Authors: Fowler Karen E. , Krein Sarah L. , Ratz David , Zawol Debbie , Saint Sanjay
Published: February 2021

We assessed the long-term sustainability of a quality improvement intervention to reduce urethral catheter use at a Veterans Affairs (VA) hospital. During the 8 years after the initial intervention, point-prevalence surveillance showed that urethral catheter use continued to decrease (OR, 0.91; 95% CI, 0.86–0.97; P = .003) and that appropriateness of catheter use remained unchanged.
Viscous backflow from a model fracture network: influence of a permeable boundary
Authors: Dana Asaf , Peng Gunnar G. , Stone Howard A. , Huppert Herbert E. , Ramon Guy Z.
Published: February 2021

The leakage from a fracture network to a surrounding medium during drainage, or backflow, driven by elastic relaxation, is considered. A network model is extended to include the effects of permeable boundaries, with the permeation through the wall assumed to be proportional to the local pressure. The regimes in which leakage is dominant relative to the parallel flow along the channel are evaluated at different times. Results show that, when the aperture of the channel is large enough, the parallel flow is greater than the permeation through the wall, and the channel thickness decreases in time,

$t$

, with a

$t^{-1/3}$

behaviour, as reported previously. However, when the aperture is small, the channel thickness decreases exponentially in time. An asymptotic investigation of the solution for a single fracture is performed and extended to network systems. The study provides insight into the influence leakage may have on squeezing-induced flows, which is relevant to natural and engineering systems.
ON THE AUTOMORPHISM GROUP OF THE UNIVERSAL HOMOGENEOUS MEET-TREE
Authors: KAPLAN ITAY , RZEPECKI TOMASZ , SINIORA DAOUD
Published: February 2021

We show that the countable universal homogeneous meet-tree has a generic automorphism, but it does not have a generic pair of automorphisms.
Progressive Law, Activism, and Lawyering in an Age of Preemption
Authors: Dyal-Chand Rashmi
Published: February 2021

Preemption is one of the most important legal doctrines for today’s progressives to understand because of its power to constrain progressive policymaking and social movement lawyering at the state and local level. By examining the detailed history of a decades-long campaign by the labor and environmental movements to improve working conditions in an industry at the heart of the global supply chain, Scott L. Cummings’s Blue and Green: The Drive for Justice at America’s Port (2018) provides a case study about the doctrine and impacts of preemption. The study also inspires lawyers and activists alike to reexamine core questions of factual relevance, representation and voice, and precedent.
The Shadows of the Past and the Work of the Future: Frederick Douglass's Temporal Theory of Democracy
Authors: Pippenger Nathan
Published: February 2021

Throughout his career, Frederick Douglass linked the achievement of an egalitarian, multiracial democracy to Americans’ perception of their collective past and future. In so doing, I argue, Douglass developed a distinctive, temporal account of democratic peoplehood. For Douglass, temporal continuity lent force and content to demands for equality—demands which would succeed only if the whole demos cultivated a specific orientation to its collective past, present, and future. Douglass offers a productive contrast to contemporary democratic theory, which often misses the importance of temporality suggested by his account and thereby risks surrendering its powerful egalitarian resources. Moreover, temporality provides a new lens on what many interpreters see as an episode of inconsistency in Douglass's thought: his brief, quickly abandoned contemplation of colonization proposals in the spring of 1861. Ultimately, Douglass turned to temporality in order to decide whether democracy for African Americans required affiliation with, or disaffiliation from, the United States.
Determining the glycaemic responses of foods: conventional and emerging approaches
Authors: Priyadarshini S R , Moses J A , Anandharamakrishnan C
Published: February 2021

A low-glycaemic diet is crucial for those with diabetes and cardiovascular diseases. Information on the glycaemic index (GI) of different ingredients can help in designing novel food products for such target groups. This is because of the intricate dependency of material source, composition, food structure and processing conditions, among other factors, on the glycaemic responses. Different approaches have been used to predict the GI of foods, and certain discrepancies exist because of factors such as inter-individual variation among human subjects. Besides other aspects, it is important to understand the mechanism of food digestion because an approach to predict GI must essentially mimic the complex processes in the human gastrointestinal tract. The focus of this work is to review the advances in various approaches for predicting the glycaemic responses to foods. This has been carried out by detailing conventional approaches, their merits and limitations, and the need to focus on emerging approaches. Given that no single approach can be generalised to all applications, the review emphasises the scope of deriving insights for improvements in methodologies. Reviewing the conventional and emerging approaches for the determination of GI in foods, this detailed work is intended to serve as a state-of-the-art resource for nutritionists who work on developing low-GI foods.
Explaining the accumulation of victimization in vulnerable children: Interpersonal violence among children traumatized by war and disaster in a children's home in Sri Lanka
Authors: Rajan Vathsalan , Neuner Frank , Catani Claudia
Published: February 2021

Research in postconflict settings indicated that children's exposure to war and natural disaster is a significant predictor of experiencing violence within their families. However, it is unclear if this effect is driven by characteristics of traumatized children or their parents. To disentangle these different factors we conducted a survey in a children's home in Sri Lanka. A total of 146 institutionalized children (aged 8 to 17) were interviewed using standardized questionnaires administered by local senior counselors in order to assess children's exposure to mass trauma, family violence, and violence in the institution as well as their mental health. Linear regression analyses revealed that, controlling for potential confounds, previous exposure to civil war was a significant predictor of violence by guardians in the children's home. In addition, previous exposure to family violence was a significant predictor of violence by peers in the institutions. A mediation analysis showed that children's internalizing and externalizing behavior problems partly mediated the relationship between violence prior to the admission to the children's home and violence in the children's home. The findings of our study provide evidence for the assumption that the transmission of mass trauma into interpersonal violence can occur independently from parents through children's psychopathology.
A bioecocultural approach to supporting adolescent mothers and their young children in conflict-affected contexts
Authors: Wuermli Alice J. , Yoshikawa Hirokazu , Hastings Paul D.
Published: February 2021

An estimated 12 million girls aged 15–19 years, and 777,000 girls younger than 15 give birth globally each year. Contexts of war and displacement increase the likelihood of early marriage and childbearing. Given the developmentally sensitive periods of early childhood and adolescence, adolescent motherhood in conflict-affected contexts may put a family at risk intergenerationally. We propose that the specifics of normative neuroendocrine development during adolescence, including increased sensitivity to stress, pose additional risks to adolescent girls and their young children in the face of war and displacement, with potential lifelong consequences for health and development. This paper proposes a developmental, dual-generational framework for research and policies to better understand and address the needs of adolescent mothers and their small children. We draw from the literature on developmental stress physiology, adolescent parenthood in contexts of war and displacement internationally, and developmental cultural neurobiology. We also identify culturally meaningful sources of resilience and provide a review of the existing literature on interventions supporting adolescent mothers and their offspring. We aim to honor Edward Zigler's groundbreaking life and career by integrating basic developmental science with applied intervention and policy.
Transforming the paradigm of child welfare
Authors: Cerulli Catherine , Cicchetti Dante , Handley Elizabeth D. , Manly Jody Todd , Rogosch Fred A. , Toth Sheree L.
Published: February 2021

As a founder of the field of applied developmental psychology, Dr Edward Zigler promoted public policy that translated scientific knowledge into real-world programs to improve the outcomes of high-risk children and families. Many researchers, practitioners, and public policy proponents have sought to carry on his legacy through integration of empirical research, evidence-based prevention and intervention, and advocacy to address a range of challenges facing families with young children. To advance the field of child maltreatment, a multidisciplinary team of investigators from the Universities of Rochester and Minnesota partnered with the Eunice Kennedy Shriver National Institute of Child Health and Human Development to create theTranslationalResearch thatAdaptsNewScienceFOR Maltreatment Prevention Center (Transform). Building on state-of-the-art research methodologies and clinical practices, Transform leverages theoretically grounded research and evidence-based interventions to optimize outcomes for individuals across the life span who have experienced, or may be at risk for, maltreatment. Inspired by the work of Dr Zigler, Transform is committed to bridging science and real-world practice. Therefore, in addition to creating new science, Transform's Community Engagement Core provides translational science to a broad audience of investigators, child-serving professionals, and parental and governmental stakeholders. This article describes Transform's purpose, theoretical framework, current activities, and future directions.
Bag-Valve-Mask versus Laryngeal Mask Airway Ventilation in Cardiopulmonary Resuscitation with Continuous Compressions: A Simulation Study
Authors: Dundar Zerrin Defne , Ayranci Mustafa Kursat , Kocak Sedat , Girisgin Abdullah Sadik
Published: February 2021

Introduction:

The 2017 International Liaison Committee on Resuscitation (ILCOR) guideline recommends that Emergency Medical Service (EMS) providers can perform cardiopulmonary resuscitation (CPR) with synchronous or asynchronous ventilation until an advanced airway has been placed. In the current literature, limited data on CPR performed with continuous compressions and asynchronous ventilation with bag-valve-mask (BVM) are available.

Study Objective:

In this study, researchers aimed to compare the effectiveness of asynchronous BVM and laryngeal mask airway (LMA) ventilation during CPR with continuous chest compressions.

Methods:

Emergency medicine residents and interns were included in the study. The participants were randomly assigned to resuscitation teams with two rescuers. The cross-over simulation study was conducted on two CPR scenarios: asynchronous ventilation via BVM during a continuous chest compression and asynchronous ventilation via LMA during a continuous chest compression in cardiac arrest patient with asystole. The primary endpoints were the ventilation-related measurements.

Results:

A total of 92 volunteers were included in the study and 46 CPRs were performed in each group. The mean rate of ventilations of the LMA group was significantly higher than that of the BVM group (13.7 [11.7-15.7] versus 8.9 [7.5-10.3] breaths/minute; P <.001). The mean volume of ventilations of the LMA group was significantly higher than that of the BVM group (358.4 [342.3-374.4] ml versus 321.5 [303.9-339.0] ml; P = .002). The mean minute ventilation volume of the LMA group was significantly higher than that of the BVM group (4.88 [4.15-5.61] versus 2.99 [2.41-3.57] L/minute; P <.001). Ventilations exceeding the maximum volume limit occurred in two (4.3%) CPRs in the BVM group and in 11 (23.9%) CPRs in the LMA group (P = .008).

Conclusion:

The results of this study show that asynchronous BVM ventilation with continuous chest compressions is a reliable and effective strategy during CPR under simulation conditions. The clinical impact of these findings in actual cardiac arrest patients should be evaluated with further studies at real-life scenes.
Exposure to aflatoxins and fumonisins and linear growth of children in rural Ethiopia: a longitudinal study
Authors: Tessema Masresha , De Groote Hugo , Brouwer Inge D , De Boevre Marthe , Corominas Arnau Vidal , Stoecker Barbara J , Feskens Edith JM , Belachew Tefera , Karakitsou Anastasia , Gunaratna Nilupa S
Published: February 2021

Objective:

We hypothesise that exposure to aflatoxins and fumonisins, measured in serum, alters protein synthesis, reducing serum protein and insulin-like growth factor 1 (IGF-1), increasing inflammation and infection, leading to child’s linear growth failure.

Design:

Children 6–35 months, stratified by baseline stunting, were subsampled from an intervention trial on quality protein maize consumption and evaluated at two time-points.

Setting:

Blood samples and anthropometric data were collected in the pre-harvest (August–September 2015) and post-harvest (February 2016) seasons in rural Ethiopia.

Participants:

102 children (50 stunted and 52 non-stunted).

Results:

Proportions of children exposed to aflatoxin G1, aflatoxin G2 and aflatoxin M1 were higher in the pre-harvest (8, 33 and 7, respectively) compared to post-harvest season (4, 28 and 4, respectively). The proportion of children exposed to any aflatoxin was higher in the pre-harvest than post-harvest season (51 % v. 41 %). Fumonisin exposure ranged from 0 % to 11 %. In joint statistical tests, aflatoxin exposure was associated with serum biomarkers of inflammation (C-reactive protein, α-1-glycoprotein) and protein status (transthyretin, lysine, tryptophan), IGF-1 and linear growth (all P < 0·01). However, exposure to specific aflatoxins was not significantly associated with any biomarkers or outcomes (all P > 0·05).

Conclusions:

Aflatoxin exposure among rural Ethiopian children was high, with large variation between seasons and individual aflatoxins. Fumonisin exposure was low. There was no clear association between aflatoxin exposure and protein status, inflammation or linear growth. A larger study may be needed to examine the potential biological interactions, and the assessment of aflatoxins in food is needed to determine sources of high exposure.