bluuebunny/crossref_metadata_2025 huggingface dataset:
Siccibacter colletis as a member of the plant growth-promoting rhizobacteria consortium to improve faba-bean growth and alleviate phosphorus deficiency stress
Authors: Chamkhi Imane , Zwanzig Jessica , Ibnyasser Ammar , Cheto Said , Geistlinger Joerg , Saidi Rym , Zeroual Youssef , Kouisni Lamfeddal , Bargaz Adnane , Ghoulam Cherki
Published: March 2023

The rhizosphere is a hot spot and a source of beneficial microorganisms known as plant growth-promoting rhizobacteria (PGPR). From the alfalfa (Medicago sativa) rhizosphere, 115 bacteria were isolated, and from the screening for PGP traits, 26 interesting isolates were selected as PGP rhizobacteria for the next tests. The objective of this study was to use a consortium of PGPR to enhance the growth of faba-bean under phosphate (P) deficiency by taking advantage of their ability to release phosphorus from rock phosphate (RP). Several examined strains were found to have a relatively high activity on P solubilization, auxin, siderophore, ammoniac production, antifungal activity, and the ability to tolerate hypersalinity and water stress. 16S rRNA gene sequencing of the collection revealed six different genera, including Bacillus (46.15%), Siccibacter (23.07%), and Acinetobacter (15.38%) which were identified as the most abundant. Three of the interesting strains (Siccibacter colletis, Enterobacter huaxiensis, and Pantoea sp.) showed high plant growth promotion traits and no antagonism with Rhizobium laguerreae. These three bacteria were retained to establish a rhizobia-including consortium. The inoculation of faba-bean plants with the consortium improved growth parameters as root and shoot dried biomasses and some physiological criteria (chlorophyll content and P uptake under low P availability conditions), and the increase reached 40%. Our study could be the first report of faba-bean growth promotion by a multi-strain PGPR-rhizobia consortium involving S. colletis, E. huaxiensis, and Pantoea sp. Thus, this consortium could be recommended for faba-bean inoculation, particularly under P-limiting conditions.
Mixed-reality-based human-animal interaction can relieve mental stress
Authors: Na Heewon , Dong Suh-Yeon
Published: March 2023

Introduction

Interacting with animals has been demonstrated to possess the healing benefits to humans. However, there are limitations in physical interaction due to COVID-19 and safety issues. Therefore, as an alternative, we created mixed-reality (MR)-based human-animal interaction (HAI) content and experimentally verified its effect on mental stress reduction.

Methods

We created three types of interactive content: observing the movement of a non-reactive virtual cat, interacting with a virtual cat whose responses can be seen, and interacting with a virtual cat whose responses can be both seen and heard. The experiment was performed by 30 healthy young women, and a mental arithmetic task was used to induce mild mental stress before experiencing each content. During the experiment, the subject's electrocardiogram was continuously recorded, and the psychological state was evaluated through a questionnaire.

Results

The results showed that MR-based virtual cat content significantly reduces mental stress and induces positive emotions after stressful situations. In particular, when the virtual cat provided audiovisual feedback, the activation amount of the parasympathetic nervous system and the increase of positive emotions were the greatest.

Discussion

Based on this encouraging research result, this method should be further investigated to see if it can replace real HAI for human mental health management.
Physiological effects of in ovo delivery of bioactive substances in broiler chickens
Authors: Kpodo Kouassi R. , Proszkowiec-Weglarz Monika
Published: March 2023

The poultry industry has improved genetics, nutrition, and management practices, resulting in fast-growing chickens; however, disturbances during embryonic development may affect the entire production cycle and cause irreversible losses to broiler chicken producers. The most crucial time in the chicks' development appears to be the perinatal period, which encompasses the last few days of pre-hatch and the first few days of post-hatch. During this critical period, intestinal development occurs rapidly, and the chicks undergo a metabolic and physiological shift from the utilization of egg nutrients to exogenous feed. However, the nutrient reserve of the egg yolk may not be enough to sustain the late stage of embryonic development and provide energy for the hatching process. In addition, modern hatchery practices cause a delay in access to feed immediately post-hatch, and this can potentially affect the intestinal microbiome, health, development, and growth of the chickens. Development of thein ovotechnology allowing for the delivery of bioactive substances into chicken embryos during their development represents a way to accommodate the perinatal period, late embryo development, and post-hatch growth. Many bioactive substances have been delivered through thein ovotechnology, including carbohydrates, amino acids, hormones, prebiotics, probiotics and synbiotics, antibodies, immunostimulants, minerals, and microorganisms with a variety of physiological effects. In this review, we focused on the physiological effects of thein ovodelivery of these substances, including their effects on embryo development, gastrointestinal tract function and health, nutrient digestion, immune system development and function, bone development, overall growth performance, muscle development and meat quality, gastrointestinal tract microbiota development, heat stress response, pathogens exclusion, and birds metabolism, as well as transcriptome and proteome. We believe that this method is widely underestimated and underused by the poultry industry.
Worker’s Satisfaction and Intention toward Working from Home—Foreign Non-EU Citizens vs. National Workers’ Approach: Case Study of Central European Countries (Visegrád Group (V4))
Authors: Alassaf Pierre , El-assaf Basem Munir , Szalay Zsigmond Gábor
Published: March 2023

The COVID-19 lockdown has brought about many sudden changes in the social and work environment, causing organizations and businesses to change work conditions to adapt to the new situation which has affected millions of workers who shifted to telework. The teleworkers’ variations in gender, age, residency situation, status as national or foreign employees, and many other aspects create differences in their response toward the telework experience. This study attempts to fill the literature gap concerning the differentiation in response between national and foreign employees’ satisfaction with the working from home experience and their future intention to work from home, with a case study of the Visegrád Group as an example from Central European countries. The study found that 84.4% of teleworkers were satisfied with working from home, but no significant difference was found between national and foreign teleworkers in their satisfaction with the telework experience; this satisfaction mainly derives from allocating the gained time to social–personal activities. A surprising result presented by this research is that, in spite of the fact that foreign non-EU-citizen workers were satisfied with the teleworking experience, they do not tend to work from home due to fears of losing their jobs and residence permits, whereas national teleworkers have the intention to work from home if given the opportunity. Another important addition of this study is the development of a new scale specifically for measuring employee satisfaction with working from home instead of using traditional job satisfaction scales.
Design of Large-Scale Space Lattice Structure with Near-Zero Thermal Expansion Metamaterials
Authors: Yu Bin , Xu Zhao , Mu Ruinan , Wang Anping , Zhao Haifeng
Published: March 2023

Thermal expansion is inevitable for space structures under the alternating temperature of outer space around the earth. This may lead to the thermal stress and deformation due to the mismatch of the coefficient of thermal expansion. Near-zero thermal expansion (Near-ZTE) is a vitally essential demand for large-scale space telescopes or antennas to preserve their spatial precision and resolution. Recently, mechanical metamaterials with superior and tailorable properties have attracted significant interest with regard to developing negative materials or ultra-property materials. In this paper, the near-ZTE space structure architected by a dual-hourglass bi-material lattice is achieved by the structural optimization method with the gradient-based algorithm. First, an hourglass lattice with adjustable structural parameters is optimized to seek the design of effective negative thermal expansion (NTE) in the thickness direction. Then, two building blocks with both NTE and legacy positive thermal expansion (PTE) are combined as a dual-layered lattice to obtain the near-ZTE. Finally, a structure with near-ZTE of about ~10−9 m/(m·K) is obtained. Furthermore, the various lattice configurations, such as the hexagonal pyramid and triangle pyramid, are investigated in detail. Finally, the natural frequencies of two near-ZTE lattices are calculated by the modal analysis method, and the stiffness is discussed for the optimal solution of space applications. This work demonstrates that the near-ZTE structure can be achieved by utilizing the negative metamaterial and structural optimization method. It provides a novel solution to design the large-scale space structures with the near-zero thermal induced deformation, and may be constructed and assembled by the on-orbit fabrication technology.
Energy Crisis—Alternative Use of Winter Bread Wheat Grain Depending on Protein Content
Authors: Klikocka Hanna , Szczepaniak Witold
Published: March 2023

Our economic analysis aimed to evaluate the profitability of winter bread wheat production based on two fundamental aspects. The first was the grainprotein content as a criterion for determining grain prices. The other was a comparative simulation of production profitability relying on grain production costs in 2015 and 2022. We used the results of a field experiment conducted in 2014 and 2015 involving winter bread wheat fertilised with nitrogen applied at progressive increments of 40 kg N ha−1 within arange from 0 to 240 N ha−1 with or without fungicide protection. We assumed that experimental factors significantly affected both the yield and the market value of grain, and hence the profitability conditioned by wheat prices on global markets. The working hypothesis of this paper is: wheat production profitability has not changed in the face of a global energy crisis. Our analysis shows that growing bread wheat generates profit when inputs are high: these inputs include high nitrogen rates and full crop protection. The real grain selling price guarantees production profitability. We should consider that, in the circumstances of a global energy crisis, the world should possibly switch to baking products from low-protein flour. Only upon such an assumption can the expenditure on fertilisers and fungicides be significantly reduced.
Effect of Planting Density on Canopy Structure, Microenvironment, and Yields of Uniformly Sown Winter Wheat
Authors: Zhang Feng , Zhang Dan , Li Lei , Zhang Zhiwen , Liang Xueqi , Wen Qinglin , Chen Guodong , Wu Quanzhong , Zhai Yunlong
Published: March 2023

A strong canopy structure is central to maximizing yield. The canopy microenvironment, which is related to crop growth and development, reflects changes in a crop’s microclimate. In this study, with the uniform sowing of winter wheat (Triticun aestivum L.), five planting densities (in 104 plants·ha−1: 123, 156, 204, 278, and 400) were established to examine how the planting density affected filling stage spikes, canopy structures, microenvironments, yields, and yield components. The large-spike Xindong 50 and multi-spike Sangtamu 4 varieties were used. The experiment was conducted over 263 days in the Xinjiang province, in a warm continental arid desert-type climate, with low precipitation. The study aimed to determine the optimal parameters for cultivation on limited land and improve the production potential. For both varieties, from anthesis to filling, increases in planting density were associated with a rapid reduction in the leaf area index of the lower and middle parts of the leaves. Canopy temperature and canopy CO2 concentration also decreased, whereas relative humidity increased. The number of grains per spike and the thousand-grain weight of both varieties decreased with increased planting density. Yields were maximized at densities of 278 × 104 and 156 × 104 plants·ha−1 for the large- and multi-spike varieties, respectively, indicating that uniform sowing improves plant uniformity, and adjusting planting density optimizes canopy structure and microenvironment. Our study provides valuable data for optimizing planting densities to ensure high yields.
Uterine Tube Resection by Vaginotomy as an Alternative to Ovariectomy in Mature Cattle
Authors: Irons Peter C. , Mooring Bryce , Warburton Natalie , Dunston-Clarke Emma , Pensini Gavin , Hay Shona , Collins Teresa
Published: March 2023

The prevention of pregnancy is desirable for female cattle destined for sale in the northern Australian rangelands for both economic and welfare reasons. Controlled access to bulls is often not feasible, nor are any non-surgical methods currently available. Many females are therefore surgically spayed. This study describes a technique for uterine tube resection (UTR), which leaves the ovaries intact and is performed using a vaginal approach, and compares the outcomes from 70 Brahman cows subjected to the procedure with 60 heifers spayed using the dropped ovary technique. The animals were monitored for 10 days following the surgery. There were no mortalities, and two animals were treated for illnesses after the UTRs and recovered. The animals subjected to both surgical procedures showed signs of pelvic discomfort and mild inflammation during recovery. The cows gained an average of 9.3 kg (SD 14.5 kg) of weight over the 10 days of the study compared to the spayed heifers, which lost 3.5 kg (SD 13.3 kg), with 19 and 63% of the animals in each of the groups losing weight, respectively. Uterine tube resection can be considered as a viable alternative to surgical spaying.
Combined Effects of Temperature and Dietary Lipid Level on Body Composition, Growth, and Freshness Profile in European Seabass, Dicentrarchus labrax
Authors: Cardoso Patrícia G. , Gonçalves Odete , Cavalheri Thais , Amorim Vânia E. , Cao Weiwei , Alexandrino Diogo A. M. , Jia Zhongjun , Carvalho Maria F. , Vaz-Pires Paulo , Ozório Rodrigo O. A.
Published: March 2023

A fish trial was carried out to evaluate the combined effects of temperature and dietary lipid level on the body composition, growth performance, and freshness profile of the European seabass (Dicentrarchus labrax). Fish were kept for 56 days at 20 °C and 24 °C and fed on two diets, with 16% and 20% lipid. At the end of the trial, fish were euthanized at two temperature conditions (0.6 °C or −0.6 °C) and kept on ice for 10 days at 4 °C to evaluate their freshness condition. Findings demonstrated that fish reared at 24 °C presented a lower lipid level and a higher daily growth index than those at 20 °C. Additionally, sensory analysis (Quality Index Method—QIM) and microbiological analysis revealed that fish reared at 24 °C showed better freshness conditions than those at 20 °C. However, the 16S rRNA metabarcoding analyses revealed a higher proliferation of genera associated with fish-spoiling bacteria in the skin microbiome of fish reared at 24 °C, i.e., Vibrio and Acinetobacter, which was not observed in the skin microbiome of fish reared at 20 °C. Nevertheless, the dietary lipid level did not have any influence on fish freshness. Therefore, our data suggest that the increase in temperature to 24 °C is beneficial for the growth and freshness profile (lower QIM and lower CFUs/cm2) of this particular species. Additionally, the lower euthanasia temperature (−0.6 °C) seems to lead to higher fish freshness than the normal temperature (0.6 °C).
Effects of Dietary Vegetable Oil Mixtures including Soybean Oil on Intestinal Oxidative Stress in Gilthead Sea Bream (Sparus aurata)
Authors: García-Meilán Irene , Fontanillas Ramón , Gutiérrez Joaquim , Capilla Encarnación , Navarro Isabel , Gallardo Ángeles
Published: March 2023

Fish oil is commonly replaced by vegetable oils in sea bream diets, but little is known about their effects on intestinal health regarding oxidative stress biomarkers. The negative effects of lipid peroxidation on digestive mucosa could have consequences in animal nutrition and welfare. In this study, five isonitrogenous (46%) and isolipidic (22%) diets with 75% of vegetable oils inclusion were evaluated: soybean oil (S) alone or different mixtures containing soybean oil with linseed (SL), linseed and rapeseed (SLR), linseed and palm (SLP), and linseed, rapeseed, and palm (SLRP). Gilthead sea bream juveniles were fed twice a day for 18 weeks. Pyloric caeca and proximal intestine samples were collected 24 h post feeding for lipid peroxidation (LPO), antioxidant enzyme activities (SOD, CAT, GPx, GST, and GR) and gene expression analyses. Pyloric caeca presented larger unhealthy changes in oxidative status than proximal intestine. Although SL-fed fish showed the highest antioxidant activities, they were unable to cope with LPO that in pyloric caeca was 31.4 times higher than in the other groups. Instead, SLP fish presented the best oxidative status, with low LPO levels, antioxidant enzyme activities, and gene expression. In summary, between the vegetable oils dietary mixtures tested, SPL would maintain better intestinal health.
Assessment of P Wave Indices in Healthy Standardbred Horses
Authors: White Rebecca , Nath Laura , Hebart Michelle , Franklin Samantha
Published: March 2023

P wave indices are used as non-invasive electrocardiographic markers of atrial remodelling in humans. Few studies have investigated their use in animals. The aim of this study was to measure P wave duration and P wave dispersion (Pd) in healthy standardbred horses and investigate variables that might influence these measurements. A 12-lead electrocardiogram was recorded at rest and P wave indices were calculated in 53 horses. A general linear model was used to investigate the main effects: age, bodyweight, sex, resting heart rate, presence of a murmur, exercise status and the number of years raced. There were significant associations with exercise status for both the maximum P wave duration and Pd, with both values being increased in strenuously exercising versus non-active horses. Furthermore, a significant moderate positive correlation was identified between the duration of exercise (number of years raced) and both Pmax and Pd. No other significant associations were identified. These findings are similar to those reported in elite human athletes versus sedentary individuals. The increases in these P wave indices most likely occur due to prolongation and heterogeneity in atrial conduction time, which are associated with structural and electrical remodelling, and may explain the increased risk of atrial fibrillation in athletic horses.
Impact of Cold Stress on Physiological, Endocrinological, Immunological, Metabolic, and Behavioral Changes of Beef Cattle at Different Stages of Growth
Authors: Kim Won-Seob , Ghassemi Nejad Jalil , Lee Hong-Gu
Published: March 2023

The purpose of this study was to investigate the effect of cold stress (CS) on the physiological, blood, and behavioral parameters of beef cattle according to their growth stage. Twelve calves in the growing stages (220.4 ± 12.33 kg, male and non-castrated) and twelve steers in the early fattening stages (314.2 ± 18.44 kg) were used in this experiment. The animals were randomly distributed into three homogenized groups (four animals each) for 14 days, namely threshold, mild–moderate cold stress (MCS), and extreme cold stress (ECS), according to the outside ambient temperature. The feed and water intakes were recorded daily. The physiological parameters, blood parameters, and behavioral patterns were measured weekly. All data were analyzed using repeated-measures analysis. The calves exposed to the ECS decreased (p < 0.064, tendency) their dry matter intake compared to the threshold and MCS groups. The HR and RT increased (p < 0.001) in the ECS compared to the threshold in calves and steers. Moreover, increased (p < 0.05) blood cortisol, non-esterified fatty acids (NEFA), and time spent standing were observed after exposure to ECS in calves and steers. However, the calves exposed to the ECS had decreased (p = 0.018) blood glucose levels compared to the threshold. In conclusion, ECS affects the dry matter intake, HR, RT, blood cortisol, NEFA, and behavioral patterns in beef calves and steers. This phenomenon indicated that beef cattle exposed to CS modulated their behavior and blood parameters as well as their physiological response to maintain homeostasis regardless of the growth stage.
Challenges and Opportunities in Antimicrobial Stewardship among Hematopoietic Stem Cell Transplant and Oncology Patients
Authors: Majumdar Anjali , Shah Mansi R. , Park Jiyeon J. , Narayanan Navaneeth , Kaye Keith S. , Bhatt Pinki J.
Published: March 2023

Antimicrobial stewardship programs play a critical role in optimizing the use of antimicrobials against pathogens in the era of growing multi-drug resistance. However, implementation of antimicrobial stewardship programs among the hematopoietic stem cell transplant and oncology populations has posed challenges due to multiple risk factors in the host populations and the infections that affect them. The consideration of underlying immunosuppression and a higher risk for poor outcomes have shaped therapeutic decisions for these patients. In this multidisciplinary perspective piece, we provide a summary of the current landscape of antimicrobial stewardship, unique challenges, and opportunities for unmet needs in these patient populations.
Increased Renal Medullary NOX-4 in Female but Not Male Mice during the Early Phase of Type 1 Diabetes: Potential Role of ROS in Upregulation of TGF-β1 and Fibronectin in Collecting Duct Cells
Authors: Casado-Barragán Felipe , Lazcano-Páez Geraldine , Larenas Paulina E. , Aguirre-Delgadillo Monserrat , Olivares-Aravena Fernanda , Witto-Oyarce Daniela , Núñez-Allimant Camila , Silva Katherin , Nguyen Quynh My , Cárdenas Pilar , Kassan Modar , Gonzalez Alexis A.
Published: March 2023

Chronic diabetes mellitus (DM) can lead to kidney damage associated with increased reactive oxygen species (ROS), proteinuria, and tubular damage. Altered protein expression levels of transforming growth factor-beta 1 (TGF-β1), fibronectin, and renal NADPH oxidase (NOX-4) are associated with the profibrotic phenotype in renal tubular cells. NOX-4 is one of the primary sources of ROS in the diabetic kidney and responsible for the induction of profibrotic factors in collecting duct (CD) cells. The renal medulla is predominantly composed of CDs; in DM, these CD cells are exposed to high glucose (HG) load. Currently there is no published literature describing the expression of these markers in the renal medulla in male and female mice during the early phase of DM, or the role of NOX-4-induced ROS. Our aim was to evaluate changes in transcripts and protein abundances of TGF-β1, fibronectin, and NOX-4 along with ROS levels in renal medullary tissues from male and female mice during a short period of streptozotocin (STZ)-induced type 1 DM and the effect of HG in cultured CD cells. CF-1 mice were injected with or without a single dose of STZ (200 mg/kg) and euthanized at day 6. STZ females showed higher expression of fibronectin and TGF-β1 when compared to control mice of either gender. Interestingly, STZ female mice showed a >30-fold increase on mRNA levels and a 3-fold increase in protein levels of kidney medullary NOX-4. Both male and female STZ mice showed increased intrarenal ROS. In primary cultures of inner medullary CD cells exposed to HG over 48 h, the expression of TGF-β1, fibronectin, and NOX-4 were augmented. M-1 CD cells exposed to HG showed increased ROS, fibronectin, and TGF-β1; this effect was prevented by NOX-4 inhibition. Our data suggest that at as early as 6 days of STZ-induced DM, the expression of profibrotic markers TGF-β1 and fibronectin increases in renal medullary CD cells. Antioxidants mechanisms in male and female in renal medullary tissues seems to be differentially regulated by the actions of NOX-4.
Antioxidant Defense Expressed as Glutathione Status and Keap1-Nrf2 System Action in Relation to Anthropometric Parameters and Body Composition in Young Women with Polycystic Ovary Syndrome
Authors: Chełchowska Magdalena , Jurczewska Justyna , Gajewska Joanna , Mazur Joanna , Szostak-Węgierek Dorota , Rudnicka Ewa , Ambroszkiewicz Jadwiga
Published: March 2023

Metabolic disorders present in women with polycystic ovary syndrome (PCOS) and the associated risk of obesity may result in increased oxidative stress and reproductive failure. Therefore, we evaluated the concentrations of reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione peroxidase (GPx), and reductase (GR), as well as nuclear factor erythroid 2-related factor 2 (Nrf2) and Kelch-like ECH-associating protein1 (Keap1) in the serum of 56 women with PCOS divided according to the visceral to subcutaneous fat surface ratio (VAT/SAT) and waist-to-hip ratio (WHR) values. Antioxidant parameter levels were measured by competitive inhibition enzyme immunoassay technique. As the VAT/SAT ratio and WHR increased, we observed significantly higher concentrations of GSSG and Keap1 protein and a lower value of the GSSG/GSH ratio (R-index), which is considered an index of cellular redox (p < 0.05). Negative correlations were found between the R-index and body weight, BMI, WHR, subcutaneous and visceral fat surface and the VAT/SAT ratio, and total body fat; positive links were found with fat free mass and total body water. Opposite associations were noted between GSSG level and the aforementioned body composition parameters. Oxidative stress characterized by a depleted reduced-to-oxidized glutathione index is associated with anthropometric and body composition parameters in women with PCOS. In particular, abdominal obesity expressed by the VAT/SAT ratio and/or WHR seems to have a negative impact on glutathione status, which may lead to a disruption of many biological cell processes. The observed negative association of Keap1 with R-index suggests that the elevated oxidative changes dependent on the VAT/SAT ratio may lead to Nrf2 activation to promote antioxidant enzyme expression. Although the GSH/GSSG index as well as the VAT/SAT ratio appear to be good indicators of oxidative status, studies on a larger group of patients should continue to confirm these links among women with PCOS.
Influence of Guardrails on Track–Bridge Interaction with a Longitudinal Resistance Test of the Fastener
Authors: Xie Kaize , Dai Weiwu , Xu Hao , Zhao Weigang
Published: March 2023

The guardrail is an indispensable part of ballasted track structures on bridges. In order to reveal its influence on the track–bridge interaction of continuous welded rail (CWR), the longitudinal resistance model of the guardrail fastener and its influential factors are established through tests. By taking a continuous girder bridge (CGB) for railways as an example, a stock rail-guardrail-sleeper-bridge-pier integrated simulation model is developed. The effects of the guardrails, installation torque of the guardrail fastener, and joint resistance of the guardrail under typical conditions are carefully examined. The research results indicate that the nominal longitudinal resistance of the guardrail fastener and the elastic longitudinal displacement of the rail prior to sliding approximately grow linearly with the growth of the installation torque. The presence of a guardrail can alleviate the track–bridge interaction in the range of the CGB, but exacerbate the interaction near the abutment with moveable bearings. This fact enables the abutment position to be considered as a new control point for the design of CWR on bridges. Considering the changing rules of the rail longitudinal force and rail gap, it is recommended that the installation torques of the guardrail fastener and guardrail joint are 40–60 N·m and 700–800 N·m, respectively. The recommended maximum longitudinal stiffness of piers for CGBs is evaluated. When the longitudinal stiffness of the pier for a CGB is lower than the recommended value, the influence of the guardrail can be neglected in the design of the CWR.
Study on the Effect of Micro-Vessels on Ablation Effect in Laser Interstitial Brain Tissue Thermal Therapy Based on PID Temperature Control
Authors: Bi Sixin , Liu Huihui , Nan Qun , Mai Xin
Published: March 2023

Laser interstitial thermal therapy (LITT) is an emerging clinical treatment for deep brain tumors, which is safe, minimally invasive, and effective. This paper established a three-dimensional model based on the LITT heat transfer model, including brain tissue, laser fiber, and straight tube vessels. Combining the PID control equation, diffuse approximation equation, Pennes heat transfer equation, and Murray’s law, the effect of micro-vessel radius and distance between vessels and fiber on the ablation temperature field during laser ablation was investigated by using COMSOL finite element software. The results showed that at a constant distance of 1 mm between the vessel and the fiber, the vessels with a radius of 0.1–0.2 mm could be completely coagulated, the vessels with a radius of 0.3–0.6 mm had cooling and directional effects on temperature distribution and thermal damage, and the vessels with a radius of 0.7–1.0 mm had cooling effects on the ablation temperature. When the vessel-fiber spacing was raised by 2 mm, 0.3–0.4 mm, vasculature had a directional influence on the temperature field; when the vessel-fiber spacing was raised by 3 mm, only 0.3 mm vessels had a directional effect on the temperature field. The range of temperature field impacted by blood flow diminishes as the distance between the optical fiber and the blood artery grows. The ablation zone eventually tends to be left and right symmetrical. In this study, we simulated the LITT ablation temperature field model influenced by tiny vessels based on PID control. We initially classified the vessels, which provided some guidance for accurate prediction and helped the accuracy of preoperative planning.
Active Semi-Supervised Learning via Bayesian Experimental Design for Lung Cancer Classification Using Low Dose Computed Tomography Scans
Authors: Nguyen Phuong , Rathod Ankita , Chapman David , Prathapan Smriti , Menon Sumeet , Morris Michael , Yesha Yelena
Published: March 2023

We introduce an active, semisupervised algorithm that utilizes Bayesian experimental design to address the shortage of annotated images required to train and validate Artificial Intelligence (AI) models for lung cancer screening with computed tomography (CT) scans. Our approach incorporates active learning with semisupervised expectation maximization to emulate the human in the loop for additional ground truth labels to train, evaluate, and update the neural network models. Bayesian experimental design is used to intelligently identify which unlabeled samples need ground truth labels to enhance the model’s performance. We evaluate the proposed Active Semi-supervised Expectation Maximization for Computer aided diagnosis (CAD) tasks (ASEM-CAD) using three public CT scans datasets: the National Lung Screening Trial (NLST), the Lung Image Database Consortium (LIDC), and Kaggle Data Science Bowl 2017 for lung cancer classification using CT scans. ASEM-CAD can accurately classify suspicious lung nodules and lung cancer cases with an area under the curve (AUC) of 0.94 (Kaggle), 0.95 (NLST), and 0.88 (LIDC) with significantly fewer labeled images compared to a fully supervised model. This study addresses one of the significant challenges in early lung cancer screenings using low-dose computed tomography (LDCT) scans and is a valuable contribution towards the development and validation of deep learning algorithms for lung cancer screening and other diagnostic radiology examinations.
Physical and Chemical Features of Hydrogen Combustion and Their Influence on the Characteristics of Gas Turbine Combustion Chambers
Authors: Shchepakina Elena Anatolievna , Zubrilin Ivan Alexandrovich , Kuznetsov Alexey Yurievich , Tsapenkov Konstantin Dmitrievich , Antonov Dmitry Vladimirovich , Strizhak Pavel Alexandrovich , Yakushkin Denis Vladimirovich , Ulitichev Alexander Gennadievich , Dolinskiy Vladimir Alexandrovich , Hernandez Morales Mario
Published: March 2023

Hydrogen plays a key role in the transition to a carbon-free economy. Substitution of hydrocarbon fuel with hydrogen in gas turbine engines and power plants is an area of growing interest. This review discusses the combustion features of adding hydrogen as well as its influence on the characteristics of gas turbine combustion chambers as compared with methane. The paper presents the studies into pure hydrogen or methane and methane–hydrogen mixtures with various hydrogen contents. Hydrogen combustion shows a smaller ignition delay time and higher laminar flame speed with a shift in its maximum value to a rich mixture, which has a significant effect on the flashback inside the burner premixer, especially at elevated air temperatures. Another feature is an increased temperature of the flame, which can lead to an increased rate of nitrogen oxide formation. However, wider combustion concentration ranges contribute to the stable combustion of hydrogen at temperatures lower than those of methane. Along with this, it has been shown that even at the same adiabatic temperature, more nitrogen oxides are formed in a hydrogen flame than in a methane flame, which indicates another mechanism for NOx formation in addition to the Zeldovich mechanism. The article also summarizes some of the results of the studies into the effects of hydrogen on thermoacoustic instability, which depends on the inherent nature of pulsations during methane combustion. The presented data will be useful both to engineers who are engaged in solving the problems of designing hydrogen combustion devices and to scientists in this field of study.
Commercial Ebullated Bed Vacuum Residue Hydrocracking Performance Improvement during Processing Difficult Feeds
Authors: Georgiev Borislav Enchev , Stratiev Dicho Stoyanov , Argirov Georgy Stoilov , Nedelchev Angel , Dinkov Rosen , Shishkova Ivelina Kostova , Ivanov Mihail , Atanassov Krassimir , Ribagin Simeon , Nikolov Palichev Georgi , Nenov Svetoslav , Sotirov Sotir , Sotirova Evdokia , Pilev Dimitar , Stratiev Danail Dichev
Published: March 2023

The Urals and Siberian vacuum residues are considered difficult to process in the ebullated bed hydrocracking because of their increased tendency to form sediments. Their achievable conversion rate reported in the literature is 60%. Intercriteria analysis was used to assess data from a commercial vacuum residue hydrocracker during processing blends from three vacuum residues: Urals, Siberian Light, and Basra Heavy. The analysis revealed that the main contributors to conversion enhancement is hydrodemetallization (HDM) and the first reactor ΔT augmentation. The increase of HDM from 40 to 98% and the first reactor ΔT (ΔT(R1)) from 49 to 91 °C were associated with a vacuum residue conversion enhancement of 62.0 to 82.7 wt.%. The developed nonlinear regression prediction of conversion from HDM and ΔT(R1) suggests a bigger influence of ΔT(R1) enhancement on conversion augmentation than the HDM increase. The intercriteria analysis evaluation revealed that the higher first reactor ΔT suppresses the sediment formation rate to a greater extent than the higher HDM. During processing Basrah Heavy vacuum residue, a reduction in hydrodeasphaltization (HDAs) from 73.6 to 55.2% and HDM from 88 to 81% was observed. It was confirmed that HDM and HDAs are interrelated. It was found that the attainment of conversion of 80 wt.% and higher during processing Urals and Siberian Light vacuum residues is possible when the HDM is about 90% and LHSV ≤ 0.19 h−1.
Application Assessment of Electrical Cables during Smoldering and Flaming Combustion
Authors: Porowski Rafał , Kowalik Robert , Ramiączek Piotr , Bąk-Patyna Paulina , Stępień Paweł , Zielecka Maria , Popielarczyk Tomasz , Ludynia Agata , Chyb Angelika , Gawdzik Jarosław
Published: March 2023

Electrical cables are a potential source of ignition and fire hazards in various types of buildings and industrial installations, as well as in all modes of transportation, including aircraft. Fires in buildings pose the greatest threat to human life and health. The composition of thermal degradation products depends mainly on the type of combustible materials and the type of combustion process—flaming or smoldering. The purpose of this paper was to determine, based on experimental studies, the effects of flaming and smoldering combustion on the response times of fire smoke detectors. In addition, the concentrations of fire gases formed in the process of duct combustion, including CO, SO2, NO2, NO, HCN, HCl, HBr and HF, were measured using an FTIR spectrometer. The results presented confirm the significant effect of the way the cable samples burned on detector tripping time. The highest concentration of smoke (Y) in the test chamber was obtained during flame combustion. It was further found that the characteristics of the cable insulation material used, such as the type of PVC, had a significant effect on the toxicity of the emitted gases. The largest amounts of toxic gases were emitted during the smoldering combustion of a cable with a plasticized PVC sheath.
Energy-Based Fatigue Assessment of Defect-Afflicted Cast Steel Components by Means of a Linear-Elastic Approach
Authors: Horvath Michael , Oberreiter Matthias , Stoschka Michael
Published: March 2023

Cast steel components are affected by manufacturing process-based imperfections, which severely limit their fatigue strength. In this work, the linear-elastic strain energy density concept is applied to assess the fatigue behaviour of bulk defect-afflicted components made of high-strength cast steel alloy G12MnMo7-4+QT. Based on analytical calculations, an energy-based design limit curve is derived which merges experimental results of notched and unnotched small–scale specimens into a statistically proven scatter band. The stress ratio dependency is also investigated. Moreover, a numerical methodology is introduced, which facilitates the energy-based fatigue assessment of complex spatial imperfections on the basis of radiographs. Validation of the established framework utilizing experimental results of defect-afflicted large–scale specimens leads to sound accordance of numerically and experimentally derived fatigue strength values, showing an average deviation of about only eight percent.
Adaptive Suppression Method of LiDAR Background Noise Based on Threshold Detection
Authors: Jiang Yan , Zhu Jingguo , Jiang Chenghao , Xie Tianpeng , Liu Ruqing , Wang Yu
Published: March 2023

Background radiation in the LiDAR detection field of view is complex and variable, and the background noise generated can easily cause false alarms in the receiver, which affects the effective detection of the system. Through the analysis of the influence of background radiation noise of LiDAR on the detection performance, an adaptive suppression method of LiDAR background noise is proposed. This method realizes the rapid suppression of background noise in the instantaneous field of view through an adaptive threshold adjustment of current steering architecture with a back-end digital-to-analog converter (DAC) correction based on the principle of constant false alarm rate (CFAR) control. Aiming at the problem of accurate noise detection and quantification in a very short time, a dynamic comparator is used to replace the traditional continuous comparator. While detecting the number of noise pulses, the measurement of the pulse duration of noise is realized, which improves the accuracy of short-time noise detection. In order to verify the actual effect of the adaptive method, experiments were carried out based on the team’s self-developed LiDAR. The experimental results show that the measured noise ratio of the adaptive mode by using this method is the lowest. Even at 12 a.m., the noise ratio of the point cloud obtained by the adaptive mode is 0.012%, compared with 0.08% obtained by the traditional mode, which proves that this method has a good ability to suppress background noise. The proportion of noise reduction of the adaptive mode is more than 80% compared with the traditional mode. It achieves noise suppression through hardware at each detection, and each adjustment can be completed within a single period of pulse detection. Therefore, it has great advantages in real-time detection compared with the back-end software noise reduction processing method, and it is suitable for the application of LiDAR in the complex background environment.
Time and Energy Optimal Trajectory Planning of Wheeled Mobile Dual-Arm Robot Based on Tip-Over Stability Constraint
Authors: Li Xianhua , Gu Yuping , Wu Liang , Sun Qing , Song Tao
Published: March 2023

Trajectory planning and avoidance of tipping are the main keys to success in the mobile dual-arm manipulation, especially when the dual-arm or moving platform is running fast. The forces and moments between wheel-terrain and body-arm have been analyzed by kinematics and force analysis of a robot to define tip-over stability constraint. Then, an improved tip-over moment stability criterion for a wheeled mobile dual-arm robot is presented and defines tip-over stability constraint based on it. To improve the motion stability of the robot, this paper presents an optimal joint trajectory planning model based on time and energy. The quintic B-spline curve and an improved NSGA-II algorithm, which are time and energy, are applied to multi-objective optimization. The simulation results show that the motion stability of a robot is improved based on the tip-over stability constraint. This trajectory planning method based on the stability constraint can be applied to other mobile robots as well.
Evaluation of Parallel Computing on MPI Version PHITS Code
Authors: Gwon Hyeok-Jun , Hwang Sun-Boong , Kim Sangrok , Kim Kum-Bae
Published: March 2023

The Message Passing Interface (MPI) technique is an old solution and an improvement on the Monte Carlo N-Particle Transport (MCNP) method’s enormous computational time, which has not been evaluated based on PHITS code—a recently developed Monte Carlo simulation code. We conducted simulations on Varian Clinac iX 6MV phase space data from the IAEA. Venselaar et al.’s method and criteria were used to validate the Monte Carlo simulation. The PC cluster has also been tested in terms of processor count and bch, which stands for unit calculation count per operation. The MPI version PHITS code’s speedup factor and the K-factor, which represent the serial portion of the cluster, were both evaluated. All calculated data met the criteria except δ2, high dose, and high gradient of the beam profile data set. It was very clear that PC clusters with MPI were better than simple nodes up to 70.6%. Additionally, the speedup factor shows a tendency to follow Amdahl’s law. At the same time, the K-factor was saturated by a certain measure. The study concludes by arguing that the cluster has limitations that come from its serial composition. If we consider how improvements in specifications affect simulation time, this cluster system could be more effective.
Promising Photoluminescence Enhancement of Tris(8-hydroxyquinoline)aluminum by Simultaneous Localized and Propagating Surface Plasmons of Ag Nanostructures
Authors: Huang Tian-Hao , Jiang Cheng-Zi , Xu Tian-Ning , Tian Zhen-Yu
Published: March 2023

The continuous performance optimization of tris(8-hydroxyquinoline)aluminum (Alq3) materials is of great significance during the commercialization process of organic light-emitting diodes (OLEDs). In incorporating Ag nanostructures into Alq3, the photophysical properties are greatly improved by the plasmon–exciton coupling effect. Localized surface plasmons (LSPs) in Ag nanoparticles (NPs) efficiently increased the absorption ability. The coexistence of LSPs and propagating surface plasmons (PSPs) in Ag nanowires (NWs) leads to a PL enhancement of 5.3-fold and a full-width at half maximum (FWHM) narrowed by 10 nm. Temperature-dependent PL measurements exhibit that the plasmonic density of states (DOS) increases with decreasing temperature below 40 °C, and the thermal exchange can be accelerated by the introduction of Ag nanostructures. Effective suppression of the thermal accumulation effect is further proved by excitation intensity (EI)-dependent PL measurements. We also found that Ag nanostructures could mainly change the y coordinates in International Commission on Illumination (CIE), leading to a higher brightness. The 5372 K color temperature of an Ag NWs-embedded composite is suitable for daylight-type fluorescent OLEDs. The results would pave an effective way for further optimizing the optical performance of light-emitting materials in OLEDs.
Applying Bayesian Models to Reduce Computational Requirements of Wildfire Sensitivity Analyses
Authors: KC Ujjwal , Aryal Jagannath , Bakar K. Shuvo , Hilton James , Buyya Rajkumar
Published: March 2023

Scenario analysis and improved decision-making for wildfires often require a large number of simulations to be run on state-of-the-art modeling systems, which can be both computationally expensive and time-consuming. In this paper, we propose using a Bayesian model for estimating the impacts of wildfires using observations and prior expert information. This approach allows us to benefit from rich datasets of observations and expert knowledge on fire impacts to investigate the influence of different priors to determine the best model. Additionally, we use the values predicted by the model to assess the sensitivity of each input factor, which can help identify conditions contributing to dangerous wildfires and enable fire scenario analysis in a timely manner. Our results demonstrate that using a Bayesian model can significantly reduce the resources and time required by current wildfire modeling systems by up to a factor of two while still providing a close approximation to true results.