bluuebunny/crossref_metadata_2025 huggingface dataset:
Anna Maccagno, estela luminosa
Authors: Cisneros Luis Jaime
Published: April 2023

La voz, circunstancialmente ausente, de Anna Maccagno se deja oír en este aniversario con ritmo vigoroso. Es que los registros civiles se esmeran en su muerte, nosotros la redescubrimos en Pando un día y otro día, en el hervor de los hornos y la terca tersura de los moldes. La gratitud y el cariño impiden que el recuerdo de Anna pueda llamarse olv!do. Es mucho lo sembrado, y hay riego constante y provechoso para asegurar el triunfo de su nombre. Todos acá en Pando sabemos cómo pervive su mirada vigilante en los momentos de la duda o el asombro: su invisible presencia es una constante certeza que nos visita, porque de ella aprendimos que la enseñanza «es un asesoramiento solidario y humano». Y Anna era (y sigue siendo) una hermosa carga de humanidad sincera. Si en Artesse sigue trabajando con el ritmo que ella instauró es porque no dudamos de que en el espíritu de cada uno está lista la semilla, que sólo necesita la hora propicia para germinar. Anna entrenó a los estudiantes a emprender la búsqueda de sí mismos. Descubrirse es rechazar la copia y emprender la búsqueda de su lenguaje y su destino. Si la sabemos cerca de nosotros es porque nos ofreció su amistad como base secreta y conjetural de toda empresa docente.
Anna, mi maestra
Authors: Mutal Lika
Published: April 2023

Es conmovedor verla. Un pequeño hombro desnudo sale de las sábanas inmaculadas. Su pelo ha sido tirado hacia atrás. Su mano, un poco hinchada como siempre descansa encima de la frazada. Una parte de ell a que no ha cambiado. Sus ojos están medio abiertos y tiene dificultades para respirar detrás de una pequeña máscara
Homenaje a la maestra
Authors: Cuba Raúl
Published: April 2023

La palabra MAESTRA y AMIGA es el emblema que magnificaste en nuestros corazones y está dedicado con todo el cariño y todos los honores aANNA MACCAGNO. Uno de los rasgos indelebles que la distingue en toda la etapa de su vida fructífera, es la entrega vocacional como Maestra, en el amplio recorrido de la docencia y, desde luego, haber formado generaciones de artistas en la especialidad de escultura.
Anna, viajera de las formas
Authors: Hamann Johanna
Published: April 2023

Anna: mujer de piel dura y manos de tierra, transparente y clara, de mirada nítida y sin medias tintas. Luminosa viajera de las formas. Te veo precisa - exacta y segura- , rescatándome del caos de lo informe, de esa magma confusa de mis ideas. Focalizándome hacia el punto de lo concreto, de lo tangible, de lo que está fuera de mí y existe por sí mismo. Llevándome hacia la comprensión de las categorías plásticas, hacia mi conciencia. Hasta que en mi corazón lleguen a calzar la forma con el fondo. Uniéndose al mundo un elemento nuevo de reconocimiento, un ser independiente que pertenecerá a la realidad, al mundo de los objetos, de las ideas. Es, entonces, cuando esta realidad «objetiva» (fuera de mi) me recupera retomándome la conciencia de ser parte de algo más grande, de algo más allá de mí misma y como quien advierte su camino, el compromiso y la responsabilidad de compartir el secreto de la creación
Las vicisitudes de la materia : una memoria interrumpida : la escultura contemporánea en el Perú
Authors: Valle Cárdenas Augusto del
Published: April 2023

Muchas veces se ha repetido la anécdota que cuenta cómo Fernando de Szyslo, allá por los años 50, al regresar de Europa dijo que en el Perú no había pintura. Lo mismo habría ocurrido con Emilio Rodríguez Larraín, cuando dijo, hace unos pocos años -a su regreso también de Europa- algo similar con respecto a la escultura. Mi propósito no es recordar declaraciones antipáticas de algunos importantes artistas peruanos, como a primera vista uno podría pensar, sino más bien iniciar una refiexión estética sobre el sentido de cierta producción en su relación con lo internacional, sobre todo tomando como referente la actual mundialización de la cultura
Modernidad, autenticidad y prácticas culturales en la sierra central del Perú
Authors: Romero Raúl R.
Published: April 2023

En «Modernidad, autenticidad y prácticas culturales en la sierra central del Perú», Raúl R. Romero trabaja en torno a los géneros musicales y a la configuración instrumental de la orquesta típica en el valle del Mantaro, analizando cómo la identidad wanka legitimada en un pasado prehispánico está estrechamente ligada a procesos modernos como la migración y la expansión del capital y el mercado en la región. El artículo ofrece así una interpretación de cómo la revitalización de la identidad regional wanka a través de la música es una manera significativa en la cual procesos nacionales y globales toman forma en esa zona.
Cambia lo superficial ... ¿cambia también lo profundo? : la fiesta de la Virgen de las Mercedes en Sechura, Piura
Authors: Diez Hurtado Alejandro
Published: April 2023

En el artículo «Cambia lo superficial... ¿cambia también lo profundo? La fiesta de la Virgen de las Mercedes en Sechura, Piura», Alejandro Diez Hurtado presenta un análisis en torno a dicha celebración, para tratar de descubrir los cambios que se observan en ella y lo que nos· pueden decir acerca de posibles transformaciones «en la fiesta misma pero también en la sociedad sechurana»
Fiesta y embriaguez en comunidades andinas del sur del Perú
Authors: Castillo Gerardo
Published: April 2023

El artículo de Gerardo Castillo, «Fiesta y embriaguez en comunidades andinas del sur del Perú», es un esfuerzo por explorar la embriaguez colectiva como una práctica expresiva y constitutiva del fenómeno festivo. Después de argumentar por la necesidad de considerarla una práctica cultural y no una patología social, Castillo afirma que a través de ella se «inscriben y actualizan formas de actuar y pensar las relaciones entre las personas, siguiendo y recreando para ello criterios étnicos, de edad y género».
PENERAPAN MODEL PEMBELAJARAN PICTURE AND PICTURE TERHADAP HASIL BELAJAR FISIKA SISWA
Authors: Widayati Ulliyah Trisna , Prihandono Trapsilo , Anggraeni Firdha Kusuma Ayu , Yusrita Yusrita
Published: April 2023

Physics subjects are not liked by student because it have a high level ofdifficulty. The impact is that student learning outcomes in physics subjects aregenerally low. The solution is an application of a learning model with picture mediaor picture and picture. This study aims to improve a student learning outcomes, aswell as analyze student respons to the picture and picture learning model applied. Thisresearch is an experimental research with a posttest-only control design. The dataanalysis technique of this study is to use the normality test and T-Test. The resultsthrough the Mann Whitney U-Test is 0.000<0.05 which indicated that there was asignificant difference in post-test results. While the student response obtained a 85%and get a “very positif” category.Key words : Learning model, Learning Outcomes, Picture and Picture
Pandemia, Saúde e Proteção: O Que nos Diz o Health at a Glance 2022?
Authors: Pita Barros Pedro
Published: April 2023

N/a.
Impactos do Bullying na Autoestima e Autoimagem
Authors: Albuquerque Paloma Pegolo de , Fragelli Raissa Maria
Published: April 2023

A aparência física é um dos principais aspectos relacionados à vivência de bullying, violência que pode afetar a autoestima dos envolvidos. Com o objetivo de investigar a ocorrência de bullying motivado por aparência física no período da adolescência e seus impactos no bem-estar de estudantes por meio dos níveis de autoimagem e autoestima, 107 estudantes universitários responderam retrospectivamente a um questionário. Do total, 66,4% apontaram ter sofrido vitimização, destacando-se violências do tipo verbal, relacional e sexual. Peso, formato corporal e cabelo foram os aspectos da aparência física relacionados à ocorrência de violência mais relatados, e 35,1% das mulheres apontaram o gênero. Os participantes obtiveram uma média alta para autoimagem e baixa para autoestima, e aqueles que sofreram bullying apresentaram escores estatisticamente inferiores aos daqueles que não sofreram. São necessários trabalhos de prevenção ao bullying sensíveis às questões de gênero.
Evaluating Change Behaviour Training Model for Improving Nutrition Knowledge and Counseling Skill among Peer Couselors in Malang District
Authors: Muslihah Nurul , Habibie Intan Yusuf , Maulidana Annisa Rizky , Kurniasari Netty Dyah , Farida Bunga , Harini Ririn
Published: April 2023

Capacity strengthening and interpersonal communication are important in social behavior change communication and would support accelerating the reduction of stunting in Indonesia. Participating actively in learning during the training model can increase capacity among the family support team and the community health workers as peer counselors. The study evaluated the changed behavior training model for nutrition knowledge and counseling skill among peer counselors. The nutrition training using active participation learning was conducted through participants' small discussions on complementary feeding problems and counseling practice. The total participation is 125 from family support teams and community health workers. The study used a mixed methodology with cross-sectional study and open interviews to explore perceived participant training on child feeding problem and couseling skills. A pre-post evaluation of nutrition knowledge showed a significant improvement score (p<0.005). At the end of the training, participants' nutrition knowledge score increased to 17 points, and the proportion of the high category of nutrition knowledge improved from 0.4% to 13.5% (p<0.005).  The change behavior training model can increase counseling skills and identify barrier factors of breastfeeding and complementary feeding among peer counselors.
Acoustic Emission Characteristics of Different Porcine Bones Under Loading
Authors: He Weikai , Yan Dongliang , Liu Muxuan , Gao Xiang , Zhang Ying , Xu Dongyu
Published: April 2023

In order to obtain the acoustic emission (AE) characteristics of fresh porcine bones of different parts under loadings, the fresh porcine femur, scapula and vertebra were investigated by using a compression testing machine and the AE instrument, respectively. The results show that the compression curve of the porcine bones has an obvious dependence on the shape of the porcine bones, and cracks can be observed with an increase of loading. Some obvious inflection points can also be found on the compression curve. The AE parameters of porcine bones under loading agrees well with the variation of the inflection points. The porcine femur exhibits the most obvious variation of AE parameters with an increase of loading and has the largest frequency band of 20--140~kHz and a dominant frequency value of 65 kHz. However, the AE energy of the scapula vertebra is weak under loading effects, and the vertebra has the smallest dominant frequency value of 25 kHz.
Inklusi Keuangan Melalui Program Layanan Keuangan Digital dan Laku Pandai
Authors:   Departemen Ilmu Ekonomi, Fakultas Ekonomi dan Bisnis, Universitas Indonesia, Sastiono Prani , Nuryakin Chaikal ,   Departemen Ilmu Ekonomi, Fakultas Ekonomi dan Bisnis, Universitas Indonesia
Published: April 2023

Penelitian ini bertujuan untuk menganalisis tingkat inklusi keuangan dari program Layanan Keuangan Digital (LKD) dan Laku Pandai. Penulis menemukan bahwa inklusi program LKD dan Laku Pandai berdasarkan penelitian ini mencapai 28% dan 43% apabila inklusi diukur dengan penggunaan layanan (inklusi akses). Namun, inklusi turun ke angka 5% dan 25% apabila inklusi didefinisikan sebagai kepemilikan rekening. Laku Pandai memiliki keunggulan dalam meningkatkan akses keuangan masyarakat yang tinggal di pedesaan, berpendidikan rendah, dan berpendapatan rendah. Pengetahuan/kepastian biaya transaksi (LKD) dan biaya akses dalam bentuk biaya transaksi dan transportasi (Laku Pandai) merupakan faktor yang penting dalam menentukan kepemilikan rekening keuangan.
MANAJEMEN KEGIATAN EKSTRAKURIKULER ROBOTIK DI SMA NEGERI 28 JAKARTA
Authors: Aini Putri Indah Nur , Santosa Heru , Supadi Supadi
Published: April 2023

Penelitian ini bertujuan untuk mengetahui proses perencanaan, pelaksanaan dan pengawasan kegiatan ekstrakurikuler Robotik di SMAN 28 Jakarta. Penelitian ini dilakukan pada bulan November 2019 hingga bulan Januari 2020 dengan objek penelitian di SMAN 28 Jakarta. Metode yang digunakan adalah metode deskriptif dengan menggunakan pendekatan kualitatif. Pengumpulan data menggunakan beberapa pedoman diantaranya pedoman wawancara mendalam, studi dokumentasi, dan observasi.

Hasil penelitian menunjukan bahwa: (1) Proses perencanaan kegiatan ekstrakurikuler Robotik dilakukan satu tahun sekali melalui rapat tahunan. (2) Pelaksanaan ekstrakurikuler Robotik dilaksanakan setiap hari Jumat pukul 15.00–Selesai. Kegiatan dilaksanakan di ruang robotik, ruang prestasi, dan ruang audio visual. Materi yang diajarkan dalam kegiatan ekstrakurikuler robotik meliputi pelatihan materi dan materi yang tertuang dalam program kerja. (3) Pengawasan Kegiatan Ekstrakurikuler Robotik di SMAN 28 Jakarta dilakukan setiap diadakannya kegiatan dengan melakukan pengawasan langsung. Hal ini betujuan memastikan bahwa kegiatan dilakukan sesuai dengan prosedur. Pengawasan dilakukan oleh wakil kepala sekolah bidang kesiswaan, Pembina, pelatih kegiatan ekstrakurikuler robotik SMAN 28 Jakarta dan orang tua. Kendala yang dihadapi dalam proses pengawasan yaitu ketika pihak sekolah tidak dapat mengawasi pelaksanaan kegiatan ektrakurikuler robotik SMAN 28 Jakarta, namun kendala tersebut dapat diatasi dengan adanya kerjasama antara pihak sekolah dan orang tua.
EVALUASI PROGRAM KARTU JAKARTA PINTAR (KJP) DI SMAN 22 JAKARTA TIMUR DENGAN PENDEKATAN CIPP
Authors: Anwar Chaerul
Published: April 2023

To increase student learning opportunities up to high school level, the DKI Jakarta government provides the Jakarta Smart Card (KJP) program for people who are classified as poor. Evaluation on the implementation of this program needs to be done to see the extent of program success. This study aims to look at the evaluation of the KJP program at SMA Negeri 22 Jakarta using the CIPP (Context, Input, Process, Output) method. The results showed that SMAN 22 had run the KJP program very well. The results of the evaluation on context aspect shows a  very good  result with 85% of implementation. The input aspects have been carried out 80% with good categories. The process aspect is running well with a percentage of 80% of the plan, and the product evaluation (output) aspect also reaches 80% of the specified criteria. The study also recommends that there should be an officer from provincial government officials to conduct home visit program to maintain the quality of KJP implementation.
KONTRIBUSI BUDAYA ORGANISASI DAN ETOS KERJA TERHADAP PRODUKTIVITAS KERJA GURU
Authors: Masduki
Published: April 2023

Penelitian ini dilakukan untuk mencari tahu adanya kontribusi budaya organisasi dan etos kerja terhadap produktivitas kerja guru PNS SD Negeri di Kecamatan Setiabudi. Metodologi dalam penelitian ialah dengan pendekatan kuantitatif model regresi linier berganda. Sampel dilakukan terhadap 126 orang guru PNS SD Negeri di Kecamatan Setiabudi. Instrumen penelitian berupa angket tertutup dalam google form berdasarkan skala likert. Pengujian hipotesis didapat dari uji t dan uji F. Hasil menunjukkan terdapat beberapa kesimpulan yaitu: 1) Budaya organisasi berkontribusi positif dan signifikan terhadap produktivitas guru PNS SD Negeri di Kecamatan Setiabudi, artinya, meningkatnya budaya organisasi akan meningkatkan produktivitas kerja guru. 2) Etos kerja berkontribusi positif dan signifikan terhadap produktivitas kerja guru PNS SD Negeri di Kecamatan Setiabudi, artinya, meningkatnya etos kerja akan meningkatkan produktivitas kerja guru. 3) Budaya organisasi dan etos kerja berkontribusi terhadap produktivitas kerja guru PNS SD Negeri di Kecamatan Setiabudi dengan nilai koefisien determinasi sebesar 0,690 atau 69%, artinya, budaya organisasi dan etos kerja secara bersama-sama memberikan kontribusi terhadap produktivitas kerja (Y) sebesar 69%.
Implementasi Manajemen Pendidikan Karakter Mewujudkan Indikator Kinerja Utama SD Islam Al Ikhlas
Authors: Wirawan Indra Fithra
Published: April 2023

Kasus anak berkarakter negatif berupa perundungan, kekerasan fisik, kekerasan psikis, dan kekerasan seksual masih terjadi di lingkungan pendidikan. Sekolah melaksanakan pendidikan karakter masih banyak menitikberatkan pada konteks pengetahuan dibandingkan pengamalan menyebabkan siswa kesulitan membentuk karakter positif. Pendidikan karakter di sekolah merupakan tahapan pembentukan karakter yang tidak kalah pentingnya dari pembentukan karakter oleh orang tua di keluarga. Sekolah harus memiliki dan menerapkan manajemen pendidikan karakter siswa untuk mencapai visi sesuai misi dan karakteristik sekolah masing-masing. Penggunaan Indikator Kinerja Utama (IKU) sebagai alat ukur kinerja sekolah dengan tepat dan akurat sangat membantu pengelola sekolah untuk menyajikan keberhasilan pencapaian tujuan sekolah untuk dipertanggungjawabkan kepada seluruh pemangku sekolah. Tujuan penelitian ini memaparkan perencanaan, pelaksanaan dan evaluasi manajemen pendidikan karakter SD Islam Al Ikhlas untuk mewujudkan IKU sekolah. Penelitian ini menggunakan pendekatan kualitatif dengan penelitian studi kasus di SD Islam Al Ikhlas. Hasil temuan penelitian yaitu: (1) Perencanaan Pendidikan Karakter dan Indikator Kinerja Utama (IKU) selaras dengan visi dan misi sekolah dengan melibatkan pemangku kepentingan sekolah. (2) Pelaksanaan pendidikan karakter melalui kegiatan sosialisasi, pembelajaran, pembiasaan dan ekstrakurikuler sesuai rencana yang telah dibuat; 3) Kontrol pendidikan karakter menggunakan Indikator Kinerja Utama (IKU) meliputi kegiatan monitoring, evaluasi dan penyampaian laporan.
Evaluasi Program Pembelajaran E-learning di Badan Pendidikan dan Pelatihan Keuangan Tahun 2020
Authors: Anggraeni Sayekti Dewi
Published: April 2023

Evaluasi Pelatihan ini bertujuan untuk menganalisis tingkat kepuasan peserta (evaluasi level reaction) terhadap Penyelenggara pelatihan e-learning,  menganalisis tingkat pemahaman peserta (evaluasi level learning), menganalisis perubahan perilaku peserta (evaluasi level behavior), dan menganalisis dampak perubahan perilaku peserta (evaluasi level result). Metode yang digunakan dalam penelitian ini adalah Metode Evaluasi Kirkpatrik empat level.  Hasil dari penelitian ini  dari keempat level evaluasi telah memenuhi kriteria berhasil tetapi masih ada perbaikan yang harus ditindaklanjuti oleh BPPK.
Peran Kepuasan Sebagai Mediasi Pengaruh Kualitas Layanan dan Brand Image Terhadap Loyalitas Lembaga Bimbel
Authors: Djafar Rosa Widyanti , Nurhajati Nurhajati , Asiyah Siti
Published: April 2023

Tujuan penelitian ini adalah untuk menganalisis hubungan secara langsung dan tidak langsung antara kualitas layanan dan brand image terhadap Loyalitas Pelanggan dalam memilih bimbel melalui kepuasan sebagai variabel mediasi di masa pandemi. Sampel dalam penelitian ini adalah orang tua siswa SD yang pernah mengikuti Bimbingan Belajar di luar sekolah. Jumlah sampel sebanyak 105 orang dengan menggunakan metode non probability sampling. Data diperoleh melalui penyebaran questioner, dan pengujian hipotesis dilakukan dengan pendekatan Structural Equation Model (SEM) berbasis Partial Least Square (PLS). Temuan Penelitian menunjukkan Secara langsung Kualitas Pelayanan dan Brand Image Berpengaruh Positif dan Signifikan terhadap Kepuasan dan Loyalitas Pelanggan. Kepuasan Pelanggan mampu memediasi pengaruh Kualitas Layanan dan Brand Image terhadap Loyalitas Pelanggan.
qEEGViz — An Open Source Web Application to Visualize the Reliability of Quantitative EEG Features
Authors: Jain Akarshi , Ramaswami Vydianathan
Published: April 2023

Background: Reliability and validity of features are important statistical concepts used by researchers to evaluate the quality of a research and draw meaningful conclusions from a study. One of the most popular ways of evaluating the reliability is by quantifying using intra-class correlation coefficient (ICC). We aim to develop a user-friendly, interactive web application that enables scholars and researchers to visualize the reliability of quantitative EEG (qEEG) features across various subjects. To our knowledge, currently there are no applications that provide a platform to visualize the reliability of features.
Results: We designed a web application qEEGViz — a freely accessible, easy-to-use, open source web-application that can be used by researchers and scholars to interactively visualize the reliability of quantitative EEG (qEEG) features in the form of topographic maps across various subjects, electrode references and epochs lengths. It is a democratic platform which gives the user flexibility to upload raw EEG signals and adjust parameters like power features, electrode reference and epoch lengths according to their requirements. Finally, the web application outputs the visualization of reliability of the qEEG features in the form of topographic map.
Conclusion: This tool is an academic contribution created solely for scholars and researchers to enhance the statistical power of the EEG experiment to detect a true treatment effect. It is a non-profitable open source web-application, independent of any operating system and can easily run on the local server. The source code and step by step instructions are provided on: https://github.com/akarshijain/qeegviz.
RPL protocol enhancement using K-Nearest Neighbor machine learning approach for IoT application
Authors: Kuwelkar Sonia , Virani Hassanali G
Published: April 2023

It is predicted that the coming decade will witness an upsurge of devices, mobile phones, sensors and actuators communicating over the Internet to enrich human lifestyle. The network design will have to ensure energy efficiency, speed and reliability for Internet of Things to be sustainable in long run. Routing of data, is one aspect which largely governs the quality of service in wireless networks. The IETF ROLL working group proposed the IPv6 Routing protocol for Low power Lossy Networks (RPL) as de-facto routing standard keeping in mind the sustainability of constrained IoT networks. The standard RPL is designed to select best route based on single parameter like hop count. The standard was kept open for researchers to experiment and augment it further. The main aim of this work is to improve the performance of RPL protocol by considering multiple metrics during selection of best route. Four routing parameters namely, hop count, delay, residual energy and link quality are chosen as criteria for deciding the best route. The K-Nearest Neighbor machine learning technique is proposed for multi criteria decision making. The K-NN computes the quality score for each candidate neighbor node and the one with highest score is selected as the most suitable parent in route towards the sink node This novel version, RPL-ML is tested in the COOJA simulator of Contiki OS. Deep dive analysis of RPL-ML by varying data rates and network density reveals that it lowers energy consumption by 18%, improves PDR by 3%, lowers delay by 20% and reduces the control overhead by 48% as compared to standard RPL implementations.
An Improved Rolling Bearing Fault Diagnosis Method using DenseNet-BLSTM
Authors: ZHAO Kaihui , Wu Sicheng , Liu Wenchang , Jia Lin
Published: April 2023

To solve the problems of the conventional rolling bearing fault diagnosis method requiring a large amount of prior knowledge and easy to introduce error artificially, this paper presents a DenseNet-BLSTM method for rolling bearing fault diagnosis. The method combines the superiority of the multi-scale deep feature extraction ability of the densely connected convolutional network (DenseNet) and the advantage of bidirectional long short-term memory (BLSTM) in sequence modeling. First, multiscale abstract features are extracted from the vibration signal of a rolling bearing using one-dimensional convolution kernels. Then, the BLSTM was used to learn the time-dependence of features. Finally, the feature information is mapped to corresponding fault modes by the fully connected layers. The experimental results show that the accuracy of the proposed method is 99.5\% in multi-load scenarios, and the method has good load adaptability and anti-disturbance ability.
Scleral sutured aniridia intraocular lens (Morcher): indications and long-term outcomes
Authors: Vakros Georgios , Bourkiza Rabia , Tarafdar Sonali , Yang Elizabeth , Charteris David
Published: April 2023

Background/Objective: To evaluate the outcomes of trans-scleral sutured posterior chamber black diaphragm intraocular lens (BDIOL) (Morcher®) implantations over 11 years.
Subjects/Methods: Retrospective case-series of patients, who underwent BDIOL implantation, identified from electronic patient records system from 2006 to 2016, Moorfields Eye Hospital. Demographics, pre/post-operative, final best-corrected visual acuity (BCVA), diagnosis, symptomatic improvement, intraoperative and postoperative complications immediate or late were collected and analysed to relate outcomes to surgical indication.
Results: Forty eyes of 38 patients (F:M 1:2.8) underwent BDIOL implantation with a mean surgical age of 46.6 years and follow-up of 44.5 months (range of 8 to 132 months). Indications included 23(57%) ocular trauma, 7(17%) congenital aniridia, 7(17%) iatrogenic lens and/or iris loss, and 3(7%) infectious keratitis. Mean preoperative BCVA was 1.64 logMAR and mean final postoperative BCVA was 0.94 logMAR with an average improvement in BCVA of 0.23 logMAR, equivalent to 1.5 lines of Snellen visual acuity. Visual results varied according to indications. Infectious cause patients had the greatest vision improvement (-0.7 logMAR), followed by trauma (-0.3 logMAR), and 25% of these achieved vision of 0.3 logMAR (6/12 in Snellen acuity) or better. Conversely, the aniridia group had the least improvement (worsened vision of 0.01 logMAR), 17 patients (42%) reported subjective improvement.
Conclusion: BDIOLs achieve reasonably good visual outcomes in eyes with complex vision threatening pathology. No significant intra-operative complications are documented and most post-operative complications are related to the pre-existing pathology. Post – trauma and iatrogenic aniridia have better outcomes compared to congenital aniridia.
Causal Association of Folic Acid Supplementary Therapy and Gastric Ulcer: A Mendelian Randomization Study
Authors: Li Fuhao , Huang Fengming , Lu Yifan , Wang Xi , Li Meng , Zhang Fan , Jiang Hao , Chen Jun , Lv Bin
Published: April 2023

Background.
The incidence of gastric ulcer (GU) remains high worldwide with limited prevention. While promising animal experiments have suggested a potential preventive role of folic acid (FA) in the development of gastric ulcers, the lack of robust clinical evidence has hindered its widespread implementation as a preventative measure. Therefore, this research aims to determine the relationship between FA supplementation and GU genetically by Mendelian randomization (MR) approach, in order to establish a foundation for developing more effective preventative strategies for this condition.
Methods.
Genome-wide association studies (GWAS) investigating the association between folic acid or folate supplementation and gastric ulcers were sourced from the UK Biobank. The primary methods for Mendelian randomization analysis were the inverse variance-weighted (IVW) methods, including fixed-effect and random-effect IVW models. Other methods used to test the robustness of the results included simple model and median, weighted model and median, as well as penalized weighted median.
Results.
MR analysis was performed to investigate the causal effect of FA adjuvant therapy on GU. Seven single nucleotide polymorphisms (SNPs) of genetic loci associated with FA adjuvant therapy were identified. The random-effect and fixed-effect IVW models revealed that genetically predicted FA complementary therapy was significantly related to the reduction of GU risk (OR, 0.870; 95% CI, 0.826–0.917, p < 0.001; OR, 0.870; 95% CI, 0.825–0.918, p < 0.001). Similar results were also observed using simple mode (OR, 0.826; 95% CI, 0.724–0.943, p = 0.030), Weighted mode (OR, 0.828; 95% CI, 0.728–0.941, p = 0.028), simple median method (OR, 0.835; 95% CI, 0.773–0.901, p < 0.001), weighted median (OR, 0.854; 95% CI, 0.794–0.919, p < 0.001) and penalised weighted median (OR, 0.849; 95% CI, 0.789–0.914, p < 0.001). The association between FA supplementary therapy and GU was not considerably driven by any individual SNP according to the leave-one-out sensitivity analysis.
Conclusions.
This MR study provides evidence from a genetic perspective that FA supplementation may decrease the risk of gastric ulcer. Clinicians should prioritize the role of FA in preventing gastric ulcers among patients.
Building Smart Surveillance Solutions for Livestock Farms
Authors: Gao Jerry , Bambrah Charanjit Kaur , Parihar Nidhi , Kshirsagar Sharvaree , Mallarapu Sruthi , Yu Hailong , Wu Jane , Yang Yunyun
Published: April 2023

Farming is an important industry in the world. With the development of artificial intelligence, the intelligence of agriculture has become a trend. Intelligent monitoring of agricultural activities is an important part of it. However, due to difficulties in achieving a balance between quality and cost, the goal of improving the economic benefits of agricultural activities has not reached the expected level. Farm supervision requires intensive human effort and may not produce strong results. In order to achieve intelligent monitoring of agricultural activities to improve economic benefits, this paper combines UAV with Deep learning model, through the combination of UAV in the agricultural industry to detect and classify objects, to achieve independent agriculture without human intervention. In this paper, a highly reliable target detection and tracking system using UAV is developed, which will be proved to be cost-effective. The system uses Deep learning method to solve the target problem. The model uses the data collected from DJI Mirage 4 UAV to detect, track and classify different types of targets. The average map accuracy of this method for target detection and tracking is 90.98\%, the average accuracy is 89.76\%, and the average recall rate is 88.78\%. In addition, this paper also compares the performance of different Deep learning models, such as YOLOv7, FASTER-RCNN, SSD, MASK-RCNN, and compares them with key evaluation indicators, and finally determines a method through the development of YOLOv7-DeepSort model.
Dental restoration operative time and analysis of the internal gap caused by the microfiltration of conventional resins (incremental technique) vs. bulk fill (single-increment technique): In vitro study
Authors: Medina-Sotomayor Priscilla , Ortega Gabriela , Aguilar José , Ordóñez Paola , Rojas Michelle , Vásquez Roxana
Published: April 2023

Background: An incremental technique used in restorations with conventional composite resin promises reduced shrinkage and increased working time; the preparation process consists of applying small increments of resin within a cavity while performing light curing in intervals, which can generate gaps between increments. Bulk fill resin allows the use of single-increment technique, improving operative time and facilitating the restoration. The objective of the present work was to determine the operative time and the internal restoration gap in the restoration–tooth interface in the cavity floor using an incremental technique for conventional resins and the single-increment technique for the bulk fill resin.
Methods: In this in vitro experimental study, the internal gaps of the restoration–tooth interfaces in the cavity floors of two conventional resins and two bulk fill resins were microscopically analyzed, and the restoration times of the single-increment technique and the incremental technique were determined.
Results: Bulk fill resins had smaller internal gap (63.31 µm) than conventional resins (333.14µm).Regarding the restoration time, the single-increment technique obtained the best results in operative time (3.52 minutes), with significant differences relative to the incremental technique.
Conclusions:The Tetric N-Ceram bulk fill resin presented better performance than conventional resins relative to the internal gap of the restoration–tooth interface in the cavity floor. In addition, the single-increment technique presented a short clinical restoration time.
Comparison of two different fixation methods in treating fractures of Type 42A2 through finite element analysis
Authors: Fang Shitao , Zhang Ling , Yang Yunqi , Wang Yun , Guo Jinkun , Mi Lei
Published: April 2023

Background At present, not all open fractures of Type 42A2 can be treated by external fixation stents, and it is inconvenient to use clinically, and external locking steel plates can be used as an alternative treatment for such patients, and the use is light and convenient. And there are few reports of finite element biomechanical analysis of external locking steel plates and external fixation brackets placed on the medial side of tibial fractures. In this study, the biomechanical properties of external locking steel plate and traditional external fixation bracket were compared by finite element method when fixing fracture of Type 42A2, which provided data support for clinical application of external locking steel plate fixation.
Methods We established a fracture of Type 42A2 model using CT data of a volunteer, and constructed two external fixation models: external locking steel plate fixation and external fixation bracket. The fracture of Type 42A2 model and two external fixation models were assembled according to the common clinical fixation methods. Finally, the axial compression, four-point bending and clockwise torsion force of the maximum load were directly loaded into the mechanical software, and the stress distribution, stress peak and overall tibial displacement in the two sets of different external fixation models were observed and compared.
Results Under the maximum load of four different experimental conditions (four-point bending, axial compression, clockwise torsion, counterclockwise torsion), the two sets of external fixation models mainly had obvious Von Mises stress concentrations in the junction between screw and tibia, screw and locking plate, self-tapping self-drilling needle and tibia, self-tapping self-drilling needle and external fixation frame, near the fracture end and near the cortical bone at the upper and lower ends of the tibia. The stress peak is about 26.67 MPa~558.77 MPa, all within the yield stress strength of titanium alloy. The peak displacement of the tibia in the external locking steel plate fixation model was smaller than that of the external fixation bracket model. In terms of structural stability, the external fixation effect of locking steel plate is better than that of single-sided external fixation.
Conclusions When the external locking steel plate fixes the fracture of Type 42A2, it is not only lightweight and convenient, but also reduces the complications in the fracture healing process, and performs better in axial compression force, bending force and torsion resistance. From the finite element biomechanical analysis, the performance of the external locking steel plate is better than that of the traditional external fixation bracket in the treatment of fractures of Type 42A2, which can meet the needs of clinical external fixation applications.
An exploration of the Roles of Lay Mental Health Workers (Cadres) in Community Mental Health Services in Indonesia: A Qualitative Study
Authors: Susanti Herni , Brooks Helen , Yulia Ice , Windarwati Heni D. , Yuliastuti Estin , Hasniah Hasniah , Keliat Budi A.
Published: April 2023

Background: Volunteers trained to support community mental health programs in Indonesia are known as ‘mental health cadres.’ These are lay people trained to provide basic support for people with mental health problems in their local communities. Their contribution has the potential to address the challenges health services currently face in remote, rural, and resource-limited settings. However, little is currently known about the implementation of this form of the lay workforce and the experiences of mental health cadres in Indonesia in particular. This study aimed to explore the role of volunteer cadres in community mental health services in Indonesia from the cadres' perspective.
Methods: The study employed a descriptive qualitative design. Purposive sampling was employed to recruit cadres with at least one year of experience across four geographical areas in Java and Sumatra, Indonesia. Data were collected utilising focus groups undertaken between July and November 2020. Due to Covid-19 restrictions, eight focus group sessions for people with mental disorders and families were carried out virtually via zoom and non-virtual, facilitated by local moderators. Data were analysed using thematic analysis.
Results: The study involved 71 cadres in four regions: Aceh, Jakarta, West Java and East Java. The majority of participants were looking after their families with a minimum of high school-level qualifications. Four themes were interpreted from the data: (1) Motivation for volunteering, (2) The role of cadres in supporting mental health services, (3) Training and support needs, and (4) Barriers and facilitators to the implementation of cadre roles in local communities.
Conclusions:Cadres reported a motivation to help people to improve their mental health and reduce the stigma associated with mental illness. Cadres also contributed to secondary and primary prevention of mental illness with some limitations. This study's results are relevant to those wishing to understand and optimise the implementation of lay workforces in resource-limited settings.
A combined integer-valued autoregressive process with actuarial applications
Authors: Hu Xiang , YAO JING
Published: April 2023

This paper proposes a modification of a combined integer-valued autoregressive (CINAR) process based on binomial thinning, which is instrumental in modelling higher-order dependence between the number of claims in an insurance portfolio. The modified CINAR process is more general and enjoys stationarity and flexibility in higher-order serial dependence modelling. Two actuarial applications of the proposed process in risk theory and credibility model are explored. As an application to risk theory, we derive the distribution of aggregate claims under a discrete-time collective risk model and examine the effect of high-order dependence on the tail-related risk measures of the aggregate claims. Next, we apply the modified CINAR process to account for the unobserved gamma heterogeneity in determining the dynamics of the predictive credibility premium. A real data analysis shows that our approach provides a superior pattern to the predictive premium calculation when compared to the outcomes of several alternative models.
Association between Sjögren’s syndrome and neuromyelitis optica spectrum disorders:a systematic review and meta-analysis
Authors: Wu Zhihong , Wang Dong , Chen Lirong , Yang Huiqing , Xianyu Kaipu
Published: April 2023

Objectives: This meta-analysis was performed to determine the association between Sjögren’s syndrome(SS) and neuromyelitis optica spectrum disorders(NMOSD).
Methods: A systematic review of all published English-language observational studies was performed. This included cross-sectional, prospective, retrospective cohort and case-control studies. Three databases (EMBASE, PubMed and Cochrane Library) up to June 2022 were searched for data collection. The study protocol was registered in PROSPERO (ID: CRD42022346810).
Results: From a total of 471 retrieved articles, 4 studies with 806 patients were eligible for this meta-analysis. 83 patients had SS with NMOSD,52 had NMOSD without SS,and 671 had SS without NMOSD. NMOSD patients with SS had a significantly higher percentage of positive ANA (OR = 19.27, 95% CI: 4.66-79.66, p<0.0001, I2 = 0%), anti-SSA (OR = 131.84, 95% CI: 19.66-884.13, p<0.00001, I2 = 0%) and anti-SSB antibodies (OR = 34.92, 95% CI: 4.09-297.91, p = 0.001, I2 = 0%) than NMOSD patients without SS. Significant differences were found for dry eyes (OR =0.52, 95% CI: 0.28-0.94, p = 0.03, I2 = 0%) and dry mouth (OR =0.31, 95% CI: 0.17-0.59, p = 0.0003, I2 = 4%) when SS patients with NMOSD were compared to those without NMOSD.
Conclusion: NMOSD patients with SS had a significantly higher percentage of positive results for ANA, anti-SSA and anti-SSB antibodies than those without SS. SS patients with NMOSD had less dry mouth and eyes than those without NMOSD,which may pose a significant diagnostic and therapeutic challenge in clinical practice.
Deciphering the Match Patterns between Gag Protein and Primer Binding Site based on Bioinformatics Analysis
Authors: Chen Shaoming
Published: April 2023

Previous studies have suggested that the genomic Gag/Gag-Pol complex is involved in recruiting the LysRS/tRNA complex, and that the selective packaging of the tRNA primer requires HIV-1 Gag and Gag-Pol. Furthermore, in vitro experiments have demonstrated an interaction between LysRS and Gag, and HIV-1 initiates the process of reverse transcription by using LysRS to bind to the genomic RNA at the primer binding site. These findings strongly suggest that the gag protein plays a critical role in matching the primer binding site. In this study, the author investigated the amino acid sequences of Gag proteins of several retroviruses and their matching primer binding sites. The analysis showed that the amino acid sequence ARG of Gag proteins of HTLV-1, HTLV-2, STLV-1, and STLV-2 match their primer binding site GGGGGCTCG in the 3'-to-5' direction, while the amino acid sequence SPR of Gag proteins of HIV-1, HIV-2, SIV, and FIV match their primer binding site GGCGCCCGA in the 3'-to-5' direction. These findings suggest a potential mechanism for the specificity of reverse transcription in retroviruses. However, it is important to note that the primer binding sites of different viruses are extremely stable, and other amino acid sequences of Gag proteins may also match these sites. Further research is needed to confirm this hypothesis. Overall, the study provides valuable insights into the mechanisms of retroviral reverse transcription, and provides an advance for further research in this area.
The need to stabilize the bacterial community present in the cultures of the marine diatom Haslea ostrearia
Authors: Peticca Aurelie , Fodil Mostefa , Chenais Benoit , Sabot Francois , Casse Nathalie
Published: April 2023

Objectives: Haslea ostrearia is a microalgae associated with the marrenine, a blue pigment known for its economic interest when it attaches to oyster gills. Complex to grow under axenic conditions, H. ostrearia probably needs its own bacterial procession to survive. Consequently, this important bacterial presence greatly complicates any study of its ecological, physiological and genomic content.
Results: We therefore tested a first approach of a protocol to control the bacterial concentration without killing the microalgae, by growing four H. ostrearia NCC 532 cultures under two culture conditions: two with and two without antibiotic treatment. We also performed a first bacterial identification method by 16S sequencing adapted to the bacterial community of H. ostrearia. The V3V4 16S region allowed precise identification of bacteria present in H. ostrearia culture. An antibiotic treatment was found as necessary to stabilize the bacterial population of the cultures before the DNA extraction.
DC targeted therapy breaks immune tolerance against neoantigens in refractory lung adenocarcinoma
Authors: Lopez-Rodriguez Lucia , Bourdely Pierre , Terza Federica La , Rospo Giuseppe , Morosi Luciano , Amadio Roberto , Piperno Giulia Maria , Volponi Camilla , Vodret Simone , Joshi Sonal , Giannese Francesca , Lazarevic Dejan , Germano Giovanni , Stoitzner Patrizia , Bardelli Alberto , Dalod Marc , Caronni Nicoletta , Guermonprez Pierre , Benvenuti Federica
Published: April 2023

The efficacy of immune checkpoint blockade (ICB) in NSCLC depends on the tumor mutational burden (TMB). However, a fraction of patients with high TMB and predicted immunogenic neoantigens (neoAgs) do not respond. Here we show that in a model of highly mutated NSCLC, cross-presenting cDC1s are required to induce broad effector CD8+ T cell responses to both strong and weak endogenous neoAgs. Importantly, cDC1 amplification by Flt3L increases immunogenicity of MHC class-I neoepitopes and promotes tumor regression, whilst PD-L1 blockade is ineffective. cDC1 density correlates to CD8+ T cell scores and prognosis, particularly in hypermutated human NSCLC. Single-cell RNA sequencing reveals the molecular determinants of Flt3L-therapy including expansion of immunogenic lung cDC1 and proliferation of cytotoxic CD8+ T cells with reduced exhaustion. We conclude that boosting cDC1 activity is critical to leverage neoAgs content for therapeutic advantage in hypermutated lung tumors that do not respond to ICB.
Ascophyllum nodosum Le Jolis Harvesting Impacts and Management Options Using GPS Tracking of Mechanical Harvesters in Nova Scotia, Canada
Authors: Sharp Glyn J. , Sharp Joshua T
Published: April 2023

Area based management of Ascophyllum nodosum Le Joli in the Canadian Maritimes has advanced over the past 60 years from open buying stations in Bays to quota-based area management under coastal leases. In 1989 the resource was divided into geographical sectors containing .9 to 17.6 ha containing 92 t to 2105 t of harvestable biomass. Sectors are the units of management plans under guidelines of the provincial government. GPS tracking mechanical harvesting to Nova Scotia began in 2017 using a new mechanical harvester in a pilot harvest. GPS tracking allowed the calculation of yield with the time, distance, and cutting swath. Harvests were conducted within target bed polygons of 200 m− 2 to 1280 m− 2. Production per hour averaged 1135 ± 169 kg h− 1 yielding 5.96 ± 1.01 kg m− 2 of swept track. The average exploitation rate within targeted polygons was 33.1 ± 14.5%. This level of geographic resolution of the harvest permits significant improvements in management practices, control of management plans, pre and post assessments of the resource. It is a method of addressing landscape scale questions relating to harvesting impacts.
Jump connection generative adversarial network for fabric defect detection
Authors: Cheng Haoming , Liang Jiuzhen , Liu Hao
Published: April 2023

Among the fabric defect detection methods, unsupervised methods are based on the principle of training a network to restore a fabric image with defects to a flawless image with a consistent background and no visible defects, and to obtain specific information about the defects by comparing the two images for defect detection. However, most of the restored images cannot remove the defective part completely, and the more obvious defects are still visible. To solve the above problem, this paper proposes the jump connection generative adversarial network for fabric defect detection (JCGAN). JCGAN uses a jump connection structure to improve the ability of the network to extract detail information by introducing the detail information from downsampling into the upsampling process. It introduces a low-dimensional loss function to control the training of the network to improve the quality of the generated images. It uses two detection algorithms (SSIM computational detection algorithm, multi-channel defect detection algorithm) to compute the disparity grayscale information of the defected and recovered images separately, and finally fuses the information from both sides to obtain more detailed detection results. Compared with the six commonly used methods, the f-value of JCGAN is improved by 13.40\% on average compared with other methods.