bluuebunny/crossref_metadata_2025 huggingface dataset:
UMA BREVE ANÁLISE DA CIDADE DE SÃO PAULO, ATRAVÉS DA PLATAFORMA 156, SOB A PERSPECTIVA DE URBAN FACILITY MANAGEMENT.
Authors: Quinello Robson , Boni Graziela
Published: August 2023

O estudo analisou os dados da plataforma 156 da cidade de São Paulo, sob a perspectiva do Urban Facility Management (UFM), apontando os problemas mais frequentes da cidade e as principais ações e contribuições de mitigação relatadas por profissionais da área de Facility Management (FM). Foi realizada uma triangulação metodológica, iniciada por fundamentação teórica seguida de pesquisa quantitativa, através de amostra das ordens de serviços do ano de 2022 extraída do canal de transparência da plataforma. Após isso, por meio de uma pesquisa qualitativa com 40 alunos de pós-graduação em FM, foram extraídas as potenciais ações e contribuições dos gestores frente aos principais desafios da cidade. Os resultados apontaram três principais demandas urbanas da cidade: ruas e bairros, cidadania e assistência social e limpeza e lixo e, respectivamente, as ações para mitigação foram:  a manutenção contínua de calçadas no perímetro das empresas, a participação de programas sociais locais e a intensificação da coleta seletiva. Atualmente o FM tem sido analisado sob a ótica urbana, ou seja, para além das fronteiras internas das organizações, posicionando-o como um elo entre os micros espaços (as organizações) e os macro espaços (equipamentos públicos) numa complexa e interconectada teia social.
Analisis Visualisasi Tokoh Ajo Kawir Pada Film Seperti Dendam, Rindu Harus Dibayar Tuntas Karya Edwin Dan Eka Kurniawan
Authors: Rifa Shandhika  , Jupriani Jupriani
Published: August 2023

There are two objectives of this research. First, analyzing the visualization of the character Ajo Kawir in the film Like Revenge, Longing Must Also Be Paid Fully. Second, to analyzing the meaning visualization of Ajo Kawir's character in the film Like Revenge, Longing Must Also Be Paid Completely. This type of research is descriptive qualitative with visual analysis method to explore various visual aspects that describe Ajo Kawir's character, including his physical appearance, facial expressions, gestures, and interactions with the environment and other characters. Data collection techniques using observation and documentation. The data analysis technique of this research is to use studies, namely Charles Sanders Pierce's Semiotics through icons, symbols, and indexes that focus on Ajo Kawir's impotence. The object of this research is the film "Like Revenge, Longing Must Also Be Paid Fully". The results of this study indicate that the impotent disease experienced by the character Ajo Kawir makes him more emotional and tries to cover it up by frequently fighting to show that he is strong. Ajo Kawir was reproached by society that people who have impotence cannot do things that are brave and strong beyond normal limits.
Türkiye’de Çocuk Sağlığının Korunması ve Geliştirilmesi İçin Önemli Bir Halk Sağlığı Politikası: Okul Diyetisyenliği
Authors: MUSLU Mücahit
Published: August 2023

Çocukluk çağı hastalıkları günümüzde artmaya devam etmektedir. Çocuklarda sağlığın korunması ve geliştirilmesi 2030 Sürdürülebilir Kalkınma Amaçları’na ulaşmak için büyük önem taşımaktadır. Hastalıkların önlenmesi ve sağlıklı yaşam tarzı davranışlarının kazanılmasında okullar çocukların büyük çoğunluğuna ulaşmak için önemli fırsatlar sunmaktadır. Okullarda önleyici halk sağlığı hizmetleri kapsamında diyetisyenler de istihdam edilmektedir. Okul diyetisyeni; bir okul veya eğitim kurumunda çalışan, öğrenciler ve okul personeli için beslenme eğitimi ve danışmanlığı veren, okuldaki yemek hizmetlerinin denetlenmesini ve düzenlenmesini sağlayan, sağlığın korunması ve geliştirilmesi için tarama, tanımlama, yönlendirme veya etkinlik düzenleme gibi faaliyetleri yürüten bir halk sağlığı profesyonelidir. Okullarda diyetisyen istihdamının çocuklarda sağlıklı yaşam tarzı davranışlarını geliştirdiği, yemek hizmetlerinin kalitesini arttırdığı ve ekonomik tasarruf sağladığı bildirilmiştir. Pek çok ülke uzun yıllardır ulusal beslenme politikaları kapsamında okullarda diyetisyen istihdam etmektedir. Türkiye’de 2023’de ilk defa T.C. Milli Eğitim Bakanlığı bünyesine 125 diyetisyen ataması yapılmıştır. Bu durum halk sağlığı hizmetleri açısından oldukça umut vaat edicidir. Bunun yanında 81 il ve 20 milyona yaklaşan öğrenci sayısı düşünüldüğünde atamaların oldukça yetersiz olduğu görülmektedir. Türkiye’de okul diyetisyenliğinin ulusal halk sağlığı politikalarına eklenmesi, yatılı okullar başta olmak üzere okullarda diyetisyen istihdamının ivedilikle sağlanması ve bu konuda gerekli yasal mevzuatların hazırlanması önerilmektedir.
Perbedaan Hasil Tes DDST pada Bayi yang Diberi ASI Eksklusif dan Susu Formula di Wilayah Kerja Puskesmas Binanga Kabupaten Mamuju
Authors: Dewi Parwati
Published: August 2023

ABSTRAK

Latar Belakang : Gizi memegang peranan penting dalam siklus hidup manusia. Pada bayi yang kekurangan gizi akan menimbulkan gangguan pertumbuhan dan perkembangan yang apabila tidak teratasi secara dini sehingga kita dapat mengukur pertumbuhan dan perkembangan anak melalui DDST.Tujuan : Penelitian ini bertujuan untuk mengetahui Perbedaan Hasil Tes DDST Pada Bayi Yang Diberi Asi Esklusif Dan Susu Formula Di Wilayah Kerja Puskesmas Binanga Kabupaten Mamuju Tahun 2022.Metode : Penelitian yang digunakan adalah penelitian observasional dengan pendekatan cross sectional study. Dimana variabel independent ( ASI Esklusif dan Susu formula) dan variabel dependent (Hasil test DDST) tujuan untuk mengetahui hubungan antara pengukuran dan pengumpulan variabelnya dilakukan searah.Hasil : Berdasarkan hasil analisa statistic yang mengunakan uji chi square diperoleh nilai P = 0,001. Oleh karena itu nilai P < 0,05. Kesimpulan : Dapat disimpulkan bahwa Ho ditolak dan Ha diterima berarti ada perbedaan Hasil test DDST pada bayi yang diberi ASI Esklusif dan Susu Formula di Puskesmas Binanga Kabupaten Mamuju Tahun 2022.

Kata Kunci : DDST, ASI Eksklusif, Susu Formula
LAPAR Sulsel's Action In Building Political Literacy In Makassar City Communities
Authors: Anjarsari Riya
Published: August 2023

LAPAR Sulsel that actively contributes to the development of political understanding and participation at the local level. Political education is a key factor in enhancing people's political participation and developing inclusive democracies. Methodology of this study is descriptive and qualitative. The researchers conducted in-depth interviews with LAPAR Sulsel staff, community members and other key stakeholders in the Makassar city area. Researchers also performed participatory observations and document analysis to collect comprehensive data. Research results show that LAPAR Sulsel has taken an important step in the development of civic education for the people of Makassar city. By providing easily accessible information, advice, training, debates and political awareness campaigns, the company has helped people better understand complex political processes and increase political participation. This has resulted in increased participation in elections, greater knowledge of political rights and an improved ability to make better informed political decisions. General conclusion of this study is that the company contributed to the development of people's political understanding, increased political participation, and made a great contribution to the development of local democracy.
LA REPRESENTACIÓN FEMENINA A TRAVÉS DE LA HISTORIA ANTIGUA Y MEDIA
Authors: Trujillo Soraya
Published: August 2023

El presente documento tiene como fin evidenciar las diferentes representaciones de la mujer y el papel que esta protagonizo en una parte de la historia. Además, se visibilizará la importancia y los oficios que realizo en el Neolítico, Paleolítico, Edad media, Mesopotamia, Antiguo Egipto y Roma. Esto tiene como fin comprender su participación y evidenciar que se ha presentado una historia de lo masculino, no de lo femenino, ya que la mujer ha vivido sometida al hombre, aun sabiendo que la mujer ha contribuido a través de la historia desde tiempos inmemoriales utilizando su voluntad, su fuerza y su imaginación, asimismo, han existido personajes que han cambiado lo estipulado por los protagonistas masculinos dándole un giro al rumbo del mundo.
música en la antigüedad y la edad media
Authors: Ramirez Lascarro David Alejandro
Published: August 2023

En este artículo se realiza un repaso a la historia de la música en la Antigüedad y la Edad Media, enfatizando en los instrumentos musicales de esos periodos y en la aparición y evolución del concepto de música y de las obras musicales en occidente desde la antigua Grecia hasta la Edad Media europea.
Editorial 2022-02
Authors: Bermudez Jairo , Verástegui Maristela , Verástegui Maristela
Published: August 2023

Editorial Hispadis 2022-02.
Fungsi Manajemen dalam Pandangan Islam
Authors: Hidayat Yayat , Maarif Miftah Nurul , Ramdani Indri , Vanista Ana
Published: August 2023

Penelitian ini bertujuan untuk mengetahui bagaimana fungsi manajemen dalam persepktif Islam. Penelitian ini menggunakan metode kualitatif dan pengumpulan data dilakukan dengan cara mencari berbagai referensi dari artikel, jurnal, dan situs lainnya. Hasil dari informasi yang ditemukan bahwa Fungsi-fungsi manajemen tidak hanya diimplementasikan oleh para pakar barat, namun Al-Qur’an juga ikut hadir dalam menjelaskan fungsi-fungsi manajemen tersebut. Adapun fungsi manajemen dalam perspektif Islam di antaranya Sedangkan fungsi manajemen dalam Islam yaitu, (التخطيط) atau Planning, (التنظيم) atau Organizing, (التنسيق) atau Coordination,(الرقابة) atau Controling,( ترغيب) atau Motivation, dan (الخلافة) atau disebut Leading.
Manajemen Perpustakaan di Era Digital
Authors: Sobirin Sobirin , Hanafi Andi Abdul , Hendra Hendra , Ari Muhammad Rifqi Al As , Sari Rini Indah
Published: August 2023

Pengaruh era digital sangat berdampak pada setiap sektor kehidupan politik, hukum, ekonomi dan termasuk pada pendidikan. Penelitian ini menggunakan metode Kualitatif deskriptif. Pengambilan data ditempuh dengan metode observasi lapangan, mewawancarai dan dokumentasi pada setiap objek yang relevan sesuai apa saja yang dibutuhkan dalam penelitian. Dalam penggunaan metode kulalitatif ini, banyak hal-hal yang mungkin akan terjadi perubahan dan kemungkinan yang mendalam. Hasil dari penelitian ini antara lain: teknologi digital telah membantu mempermudah menjemen perpustakaan dalam perencanaan penggunaan administrasi/ pencatatan di SMKN 1 Cijulang. Selain itu, observasi terkait pengaruh era digital terhadap perpustakaan sekolah telah mempengaruhi pada layanan teknis perpustakaan sekolah di SMKN 1 Cijulang yang merupakan bagian dari implementasi dari perencanaan terhadap perpustakaan sekolah.
Investasi Pendidikan untuk Peningkatan Kesejahteraan
Authors: Iqomah Riksa , Marliani Rina
Published: August 2023

Dalam penulisan karya ilmiah ini, digunakan metode penelitian kepustakaan untuk memperoleh informasi yang diperlukan. Metode penelitian kepustakaan dilakukan dengan mengumpulkan informasi atau informasi tertulis dari berbagai literatur seperti buku, surat kabar dan berbagai artikel di internet, yang dapat mendukung penelitian ini. Hasil penelitian ini ialah bahwa investasi dalam pendidikan dapat meningkatkan modal manusia. Pendidikan tidak hanya meningkatkan pengetahuan, keterampilan, produktivitas dan pendapatan tetapi juga dapat meningkatkan kesejahteraan. Berinvestasi dalam pendidikan adalah alat terpenting bagi negara dan perusahaan untuk membangun tenaga kerja yang berkualitas.
Rate of Return Investasi di Dunia Pendidikan
Authors: Hidayatulloh Arlan , Holisoh Elis
Published: August 2023

Penelitian ini bertujuan untuk mengulas rate of return dalam konteks investasi di bidang Pendidikan. Penelitian ini merupakan penelitian kualitatif. Pendekatan yang digunakan adalah penelitian kepustakaan. Berdasarkan hasil kajian ini, dapat disimpulkan bahwa Investasi pendidikan memberikan nilai balik (rate of return) yang lebih tinggi dari nvestasi fisik di bidang lainnya. Nilai balik pendidikan ialah perbandingan antara total biaya yang dikeluarkan untuk membiayai pendidikan dengan total pendapatan yang akan diperoleh setelah seseorang lulus dan memasuki dunia kerja. Diharapkan dari investasi ini manfaat yang diperoleh jauh lebih besar dari pada biayanya.
Pemetaan Tingkat Kesejahteraan di Desa Tangaran Kabupaten Sambas Kalimantan Barat Menurut Indikator Badan Kependudukan dan Keluarga Berencana Nasional (BKKBN)
Authors: Rojia Rojia , Maya Maya , Santi Santi
Published: August 2023

Desa Tangaran merupakan desa yang memiliki presentase luas wilayak terluas ke 3 (tiga) setelah desa Simpang Empat dan desa Semata se kecamatan Tangaran. Desa ini juga masih termasuk ke dalam kategori desa berkembang dengan jumlah penduduk sebanyak 3566 jiwa. Tingginya jumlah keluarga miskin menggambarkan kurangnya tingkat kesejahteraan keluarga yang ada di Desa Tangaran sehingga pemerintah memberikan bantuan berupa Program Keluarga Harapan (PKH) untuk membantu mensejahterakan keluarga miskin yang ada di desa Tangaran. Dalam penelitian ini penulis menggunakan metode pendekatan penelitian secara kuantitatif deskriptif dengan indikator dari BKKBN. Metode yang digunakan untuk menentukan jumlah sampel dalam penelitian ini adalah menggunakan rumus slovin yakni sebanyak 43 KK yang di ambil dari populasi 1037 KK. Dari penelitian ini diperoleh temuan bahwa responden di Desa Tangaran didominasi oleh responden pada Tingkat Kesejahteraan Tahapan Pra Sejahtera. Berdasarkan pemetaan tingkat Kesejahteraan di Desa Tangaran, Dusun Sadayan berada di Tahapan Pra Sejahtera, Dusun Pendawan berada di Tahapan Keluarga Sejahtera II, dan Dusun Pandam berada di Tahapan Keluarga Sejahtera I.
Pembelajaran Kognitifistik sebagai Upaya Respon Terhadap Dampak IPTEK
Authors: Janah Salsabila Ajizatul , Rohman Rizki Idul , Nurzaman Dede Ilman
Published: August 2023

Perkembangan IPTEK terhadap dunia Pendidikan dapat memengaruhi pola pikir pelajar baik dalam hal positif maupun hal negatif dengan terganggunya stimulus otak seseorang sehingga dapat mengganggu kesehatan mental. Kita juga menyaksikan banyaknya kalangan remaja yang terkadang menyalahgunakan teknologi hanya untuk kesenangan sesaat saja. Namun, semua itu dapat diubah dengan menerapkan beberapa teori yang terdapat pada psikologi pendidikan, salah satunya yaitu dengan menerapkan teori kognitif. Penelitian ini menggunakan metode studi literatur dengan sumber berupa buku-buku dan jurnal. Hasil kajian ini menyatakan bahwa pada pembelajaran psikologi Pendidikan terdapat beberapa alternatif terapi kognitif yang dapat bermanfaat terhadap pola pikir seorang pelajar maupun individu supaya dapat terarahkan dalam mengambil keputusan serta bertingkah laku dengan sehat dan dapat mengontrol emosional.
INDIAN CLASSICAL AND SPIRITUAL MUSIC IN NAAD YOGA PRACTICE FOR HEALING AND HEALTHY WELL-BEING FROM THE STANDPOINTS OF THE MODERN SCIENCE
Authors: Arun Dubey
Published: August 2023

Indian classical and spiritual music has a rich traditions and long history of use in healing and healthy well-being, and here it is closely related to Naad yoga. These effective practices are based on ancient knowledge and experience accumulated over thousands of years, which are of great interest today.

Holistic understanding of Health considers physical body as a part of body system, including other subtle energy layers – koshas - and corresponding energy structure. This article gives an introduction of the Indian musical system in general and Raag as its element, and Naad Yoga - as an ancient system of knowledge, which can give a new fresh sight on the Musical Therapy. It is especially important to comprehend these achievements of Indian civilization from modern scientific positions.

We will try to understand how spiritual sound or Mantra works and what scientifical facts lie at its basis – frequencies and their effects on human body and mind. What are the benefits and the uniqueness of Indian classical and spiritual music and therefore, how it can be used in healing and maintaining of healthy well-being.

This article is composed of materials, which were given to Russian students on the classes of Naad Yoga by the author (together with Indian classical vocal lessons) and are based on the present Ph.D. research work «Musical Naad, Mantra, Stuti and Their Effects on Human Body, Mind and Soul» conducted on the base of R.M.T. Kala Sangeet University (Vishwavidyalaya), Gwalior, India.
Stigma among Parents of Children with Autism: An Integrative Review
Authors: Thi Loan Khanh  , Mai Thi Lan Anh , Phương Anh Hoang
Published: August 2023

The number of children diagnosed with autism is increasing around the world. The role of parents is vital in caring for children with autism, but stigma is a challenging and prevalent aspect that families face in raising and caring for them. This integrative review, undertaken by nurse researchers in 2022, synthesized the existing knowledge of current studies about stigma status and the factors relating to stigma among parents of children with an autism spectrum disorder. The electronic databases searched included PubMed, CINAHL (EBSCO), EMBASE, and Scopus, using the keywords “stigmatization,” “parents,” and “autism.”
Thirty-six studies without time limits were included in this review, 16 qualitative, 15 quantitative, four mixed-method, and one interventional study. The results indicated that stigma was common among parents of children with autism in all studies. However, there was a difference related to cultural stigma among parents with autism in Western, Asian, and Middle Eastern countries. Both modifiable and unmodifiable factors were associated with the stigma, for example, parents’ age, marital status, child’s behavior, and social support. Further longitudinal studies on stigma should be conducted in low-resource areas with different caregivers in large sample sizes to identify the prevalence of stigma and stigma changes among parents of children with autism. This review’s results provide evidence for further intervention studies that address factors related to reducing stigma among parents of children with autism. Moreover, healthcare professionals, including nurses working with these families, should assess the level of stigma among these parents to provide timely support.
Mitigating the Post-operative Swelling Tsunami in Total Knee Arthroplasty: A Call to Action
Authors: Wickline Andrew , Cole Windy , Melin Mark , Ehmann Suzie , Aviles Frank , Bradt Jennifer
Published: August 2023

Total knee arthroplasty (TKA) is a treatment option for individuals with symptomatic osteoarthritis who have failed conservative therapy. In this manuscript the authors describe the pathophysiology of post-operative edema and explore the patient dependent factors potentially contributing to lymphatic dysfunction and thus directly influencing the TKA postoperative course. A proposed multimodal perioperative protocol is presented that focuses on identifying limb edema/lymphedema preoperatively, intraoperative technique changes that may decrease swelling post-TKA.
PERSPEKTIF APARATUR SIPIL NEGARA TERHADAP EFEKTIVITAS DAN EFISIENSI WORK FROM ANYWHERE
Authors: Hidayat Taufik , Ria Mai Damai , Ria Mai Damai , Hdiwasono Kodar
Published: August 2023

Rencana pemberlakuan kebijakan Work From Anywhere bagi para aparatur sipil negara  diklaim dapat meningkatkan kepuasan kerja, komitmen organisasi, dan mendorong karyawan untuk memberikan performa terbaik. Rencana ini berangkat dari “keberhasilan” kebijakan Work From Home selama masa pandemi yang mampu meningkatkan kesejahteraan dan kinerja aparatur sipil negara, sehingga perlu di-upgrade menjadi Work From Anywhere. Wacana ini menimbulkan pro dan kontra. Masyarakat memandang bahwa kinerja dan produktivitas aparatur sipil negara masih belum sesuai harapan sehingga dikhawatirkan sistem kerja Work From Anywhere akan menghambat pelayanan publik. Sementara itu, pemerintah menilai kebijakan Work From Anywhere mampu menciptakan efektivitas dan efisiensi. Dengan demikian perlu dilakukan kajian secara komprehensif terhadap wacana ini.Salah satu kajian yang dilakukan adalah perspektif dari apartur sipil negara itu sendiri terhadap efektivitas dan efisiensi pelaksanaan Work From Anywhere. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Prosedur yang dilakukan dalam pengumpulan data adalah survei terhadap aparatur sipil negara  di tingkat pusat maupun daerah. Berdasarkan perspektifaparatur sipil negara, sistem kerja Work From Anywhere lebih efektif dan efisien dibanding sistem kerja Work From Office. Efektivitas dan efisiensi pada Work From Anywhere terutama pada dimensi biaya, jumlah pekerjaan yang dapat diselesaikan, kendala yang dihadapi, kenyamanan, pencapaian sasaran/tujuan, adaptasi kerja, metode kerja dan pelaksanaan standard operational procedure. Selain itu, mayoritas aparatur sipil negara lebih memilih bekerja dengan sistem Work From Anywhere dengan persentase di atas 50%. Meski demikian tidak seluruh aparatur sipil negara yang memilih Work From Anywhere menolak Work From Office, sebagian responden tidak keberatan bekerja dengan sistem Work From Anywhere maupun Work From Office.
ANALISIS GAYA KOMUNIKASI PEGAWAI NEGERI SIPIL GENERASI MILENIAL DI BADAN KEPEGAWAIAN NEGARA
Authors: Kurniati Mia
Published: August 2023

Yth. Editor Jurnal BKN. 

di Jakarta

 

Dengan Hormat, 

Bersama ini saya mengirimkan jurnal yang telah saya buat tahun 2020 dengan judul  Analisis Gaya Komunikasi Pegawai Negeri Sipil Generasi Milenial di Badan Kepegawaian Negara Mohon perkenannya untuk dapat diedit. 

Demikian atas perhatian Bapak/Ibu Editor saya ucapkan terima kasih
MANAJEMEN TALENTA BERDASARKAN SMART ASN DI LINGKUNGAN PEMERINTAH (SEBUAH KERANGKA KONSEPTUAL)
Authors: Firmansyah Ardy
Published: August 2023

Pengembangan karir PNS melalui manajemen talenta merupakan entitas yang diprioritaskan oleh pemerintah, terutama dengan menyelaraskan perkembangan teknologi di era disrupsi saat ini. Oleh karena itu, digitalisasi tidak dapat dihindari. Smart ASN merupakan keniscayaan dalam menghadapi perubahan revolusi industri 4.0. Namun, solusi ini dapat terjebak dalam pola pikir esensialis, yaitu makna urgensi Smart ASN yang hadir tanpa dasar kondisi objektif tertentu. Oleh karena itu, perlu dilakukan penelitian ini untuk menggali akar ide Smart ASN, menggali aspek-aspek yang masih kurang dalam konsep Smart ASN yang dikaitkan dengan manajemen talenta sebagai dasar pengembangan karir ASN. Tujuan dari penelitian ini adalah untuk memberikan kerangka konseptual yang komprehensif mengenai implementasi desain manajemen talenta berbasis Smart ASN di Lingkungan Pemerintahan. Penelitian ini menggunakan pendekatan kualitatif melalui metode analisis deskriptif berdasarkan studi kepustakaan. Teknik analisis data menggunakan triangulasi data dari sumber literatur kemudian dijabarkan untuk mengembangkan kerangka konseptual implementasi smart ASN berbasis manajemen talenta. Kebaruan hasil adalah merumuskan kerangka konseptual penerapan manajemen talenta dengan tahapan strategis mulai dari talent acquisition, talent development, talent retention, talent replacement serta monitoring and evaluation. Semua tahapan dijabarkan dengan prinsip Smart ASN yang terdiri dari profesional, strategi dan inovasi.
Acceso de estudiantes con NEE en el nuevo sistema de admisión escolar: un estudio en la Región de los Los Lagos
Authors: Sánchez Bravo Alejandra , Pérez Godoy Pamela
Published: August 2023

En Chile, la entrada en vigor de la Ley de Inclusión Escolar del año 2016 cambió la forma en que las familias seleccionan los establecimientos educacionales y convirtió el acceso escolar en un asunto relevante dentro del debate de las políticas educacionales. El objetivo de este estudio fue determinar si el nuevo Sistema de Admisión Escolar (SAE) introduce diferencias en el acceso de los niños y niñas con Necesidades Educativas Especiales (NEE) en los colegios particulares subvencionados sin programas de integración  escolar de una comuna de la región de Los Lagos, con este fin se analizaron los datos en términos de cantidad de matrícula, tipo de financiamiento, entrega de apoyo especializado  y sello institucional de los períodos 2016 y 2017 (antes del SAE) y 2018 (implementación del SAE).  El estudio se adscribe al enfoque cuantitativo de investigación, participaron 14 establecimientos (73,6% de la población). Los resultados del estudio señalan que en este tipo de instituciones la implementación del SAE no introduce diferencias estadísticamente significativas en el acceso de estudiantes con NEE. Por el contrario, se observó un mayor acceso de niños y niñas con NEE antes de la implementación del SAE.
Adquisición y Lenguaje: la perspectiva fundacionalista de Tomasello y el segundo Wittgenstein
Authors: Albornoz Mora Nicolás
Published: August 2023

A través de las investigaciones del psicólogo y lingüística Michael Tomasello y las reflexiones filosóficas del segundo Wittgenstein, este artículo busca desprender una perspectiva fundacionalista sobre el lenguaje. Esta visión propone que el fenómeno de la adquisición es la fundación del lenguaje, tanto de sus semántica como de su sintaxis. Para realizar esto, se hará primero una lectura de las Investigaciones Filosóficas de Wittgenstein haciendo énfasis en como la adquisición juega un rol fundamental en su teoría, y luego se entenderán los conceptos como juegos del lenguaje y seguimiento de reglas desde esta perspectiva. Luego se verá la teoría de adquisición del lenguaje basada-en-el-uso de Tomasello, pasando por los procesos fundacionales de lectura de intenciones y marcos de atención conjunta. También se indagará sobre su explicación del desarrollo de la sintaxis en infantes. Una vez obtenidos estos fundamentos, se verá un posible problema que el proceso de lectura de intenciones podría suscitar y una solución desde la perspectiva ontogenética del lenguaje. Para finalizar, se buscará mostrar que ambos autores consideran al uso lingüístico anclado en la circunstancia como el significado de las palabras, que el fenómeno de la corrección lingüística es público y social, y que la interacción es lo que permitirá el desarrollo de la gramática. Para finalizar, se observará como a partir de estas conclusiones se sigue directamente una visión fundacionalista de la adquisición.
The Influence of Using Instagram's Social Media Account @Neohistoria.Id In Fulfilling Followers' Information Needs
Authors: Prayoga Arya Aldin , Saktisyahputra
Published: August 2023

Today the world has entered the era of globalization, various kinds of technology are growing very rapidly. The growth of technology is also based on human needs, humans have a need for information, on the development of technology, humans can easily access the information needed through the media. This information is of course obtained through mass media such as television, radio, magazines, films, newspapers, tabloids, and mass media, namely letters, telephones, posters, telegrams, banners and so on. One of the accounts that uses Instagram social media to spread information is Instagram @Neohistoria.id. This study uses quantitative methods. The author is interested in knowing the effect of using Instagram social media accounts on meeting information needs. The purpose of the study was to determine the effect of using the Instagram @Neohistoria.id social media account on meeting the information needs of followers and to find out how much influence social media had on meeting information needs. Data collection in this study is by distributing questionnaires to 100 respondents who were determined through accidental sampling. The data obtained were analyzed using validity tests, reliability tests, simple regression tests, correlation coefficients, coefficients of determination, and T tests. The results of this study obtained positive regression results, which means that there is effectiveness of social media in meeting information needs.
Class Management In An Effort To Improve The Effectiveness Of The Teaching Process Of Islamic Religious Education At Vocational School Of Padindi West Jakarta
Authors: Apipudin  , Iskandar Rudi , Zaya Amer Shebl
Published: August 2023

This research aims to find out and test empirical data related to classroom management in an effort to improve the effectiveness of the teaching process of teaching Islamic religious education at SMK Padindi kamal west Jakarta. The results of the study prove that there is an increase in the effectiveness of the teaching and learning process and is very significant between class management in an effort to increase the effectiveness of the teaching and learning process of Islamic religious education at SMK Padindi Kamal, West Jakarta, reaching 47.43% which is included in the quite satisfactory category given by respondents based on research on opinions about classroom management applied from the principals and teachers of Islamic Religious Education at SMK Padindi Kamal, West Jakarta.
Flat design as visualization of flat ontologies
Authors: Pankratova Aleksandra Vladimirovna
Published: August 2023

The object of this research is design as a semiotic embodiment of the modern worldview, the quintessence of which are flat ontologies. The subject of the study is parallelism in the philosophy of flat ontologies and modern flat design. The purpose of this study is to explicate the philosophical problem of modern design, which is a consequence of the unconscious expression by designers of the philosophy of flat ontologies. The philosophy of flat ontologies struggles with anthropocentrism, insisting that a person should not have a privileged ontological status compared to other objects. In the philosophy of flat ontologies, a machine or a neural network are agents of action in the same way as a person. Modern flat design is an expression of this position, since the modern visual information environment is less and less adapted to human organs of perception, more and more transhumanistic. Both flat design and flat ontologies are a consequence of the horizontally oriented, materialistic line of philosophy, which forms the worldview of modern society. Thanks to the explication of the problem of flat design, it can be understood that the horizontally oriented line of philosophy is problematic for the further existence of man. The main conclusion of the study is that the horizontally oriented line in philosophy – materialism and positivism – in their logical development lead to the philosophy of flat ontologies, which postulates the same ontological status for human and non-human agents. Such a position is antihuman and transhumanistic, and this becomes evident in the philosophical analysis of modern design. The main stylistics of modern design is a flat design, which uses fourth-order simulacra as the main type of signs. The use of simulacrum signs in design creates an environment that is increasingly less adapted to human organs of perception, a transhumanistic environment.
Differences in the inflammatory proteome of East African and Western European adults and associations with environmental and dietary factors
Authors: Temba Godfrey S , Vadaq Nadira , Kullaya Vesla , Pecht Tal , Lionetti Paolo , Cavalieri Duccio , Schultze Joachim L , Kavishe Reginald , Joosten Leo AB , van der Ven Andre J , Mmbaga Blandina T , Netea Mihai G , de Mast Quirijn
Published: August 2023

Non-communicable diseases (NCDs) are rising rapidly in urbanizing populations in sub-Saharan Africa. Assessment of inflammatory and metabolic characteristics of a urbanizing African population and the comparison with populations outside Africa could provide insight in the pathophysiology of the rapidly increasing epidemic of NCDs, including the role of environmental and dietary changes. Using a proteomic plasma profiling approach comprising 92 inflammation-related molecules, we examined differences in the inflammatory proteome in healthy Tanzanian and healthy Dutch adults. We show that healthy Tanzanians display a pro-inflammatory phenotype compared to Dutch subjects, with enhanced activity of the Wnt/β-catenin signalling pathway and higher concentrations of different metabolic regulators such as 4E-BP1 and fibroblast growth factor 21. Among the Tanzanian volunteers, food-derived metabolites were identified as an important driver of variation in inflammation-related molecules, emphasizing the potential importance of lifestyle changes. These findings endorse the importance of the current dietary transition and the inclusion of underrepresented populations in systems immunology studies.
Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors
Authors: Lin Miin S. , Jo Se-Young , Luebeck Jens , Chang Howard Y. , Wu Sihan , Mischel Paul S. , Bafna Vineet
Published: August 2023

Extrachromosomal DNA is a common cause of oncogene amplification in cancer. The non-chromosomal inheritance of ecDNA enables tumors to rapidly evolve, contributing to treatment resistance and poor outcome for patients. The transcriptional context in which ecDNAs arise and progress, including chromosomally-driven transcription, is incompletely understood. We examined gene expression patterns of 870 tumors of varied histological types, to identify transcriptional correlates of ecDNA. Here we show that ecDNA containing tumors impact four major biological processes. Specifically, ecDNA containing tumors upregulate DNA damage and repair, cell cycle control, and mitotic processes, but downregulate global immune regulation pathways. Taken together, these results suggest profound alterations in gene regulation in ecDNA containing tumors, shedding light on molecular processes that give rise to their development and progression.
Mechanical coupling coordinates microtubule growth
Authors: Leeds Bonnibelle K. , Kostello Katelyn F. , Liu Yuna Y. , Biggins Sue , Asbury Charles L.
Published: August 2023

During mitosis, kinetochore-attached microtubules form bundles (k-fibers) in which many filaments grow and shorten in near-perfect unison to align and segregate each chromosome. However, individual microtubules grow at intrinsically variable rates, which must be tightly regulated for a k-fiber to behave as a single unit. This exquisite coordination might be achieved biochemically, via selective binding of polymerases and depolymerases, or mechanically, because k-fiber microtubules are coupled through a shared load that influences their growth. Here, we use a novel dual laser trap assay to show that microtubule pairs growing in vitro are coordinated by mechanical coupling. Kinetic analyses show that microtubule growth is interrupted by stochastic, force-dependent pauses and indicate persistent heterogeneity in growth speed during non-pauses. A simple model incorporating both force-dependent pausing and persistent growth speed heterogeneity explains the measured coordination of microtubule pairs without any free fit parameters. Our findings illustrate how microtubule growth may be synchronized during mitosis and provide a basis for modeling k-fiber bundles with three or more microtubules, as found in many eukaryotes.
All eyes on FOXC2
Authors: Yan Wei , McCarrey John R
Published: August 2023

New evidence in mice suggests that cells expressing the transcription factor FOXC2 may form a reservoir of quiescent stem cells that contributes to sperm formation.
Effects of the CYP3A inhibitors, voriconazole, itraconazole, and fluconazole on the pharmacokinetics of osimertinib in rats
Authors: Lou Yutao , Song Feifeng , Cheng Mengting , Hu Ying , Chai Yitao , Hu Qing , Wang Qiyue , Zhou Hongying , Bao Meihua , Gu Jinping , Zhang Yiwen
Published: August 2023

Background

Osimertinib, as third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is the first-line treatment approved to treat advanced T790M mutation-positive tumors. Triazole antifungals are therapeutic drugs for cancer patients to reduce the risk of opportunistic fungal infections. Our objective was to investigate whether three triazole antifungals (voriconazole, itraconazole, and fluconazole) could change the pharmacokinetics of osimertinib in rats.

Methods

The adult male Sprague-Dawley rats were randomly divided into four groups (n = 6): control (0.3% CMC-Na), and voriconazole (20 mg/kg), itraconazole (20 mg/kg), or fluconazole (20 mg/kg) combined with osimertinib (10 mg/kg) group. Tail vein blood samples were collected into heparin tubes at various time points within 0–48 h after osimertinib administration. Osimrtinib’s plasma concentration was detected using HPLC-MS/MS system equipped with a Waters XBridge C18 column, with the mobile phase consisting of acetonitrile and 0.2% formic acid water at a flow rate of 0.5 mL/min.

Results

Co-administration with voriconazole or fluconazole increased the Cmax of osimertinib by 58.04% and 53.45%, respectively; the AUC0–t increased by 62.56% and 100.98%, respectively. However, when co-administered with itraconazole, the Cmax and AUC0–t of osimertinib only increased by 13.91% and 34.80%, respectively.

Conclusions

Our results revealed that the pharmacokinetics of osimertinib were significantly changed by voriconazole and fluconazole in rats, whereas it was slightly affected by itraconazole. This work will contribute to a more comprehensive understanding of the pharmacokinetic properties of osimertinib when co-administered with triazole antifungals.
SINERGIAS ENTRE A ECONOMIA AZUL E O ODS 14: CAMINHOS PARA UM FUTURO SUSTENTÁVEL
Authors: E Silva Fábio Coelho Netto Santos , Barro Sergio Ricardo da Silveira
Published: August 2023

The ocean is considered the new economic frontier due to its potential for resource wealth and economic growth driver. However, the ocean faces increasing pressures from overexploitation, pollution, biodiversity decline and climate change. In this context, the concept of Blue Economy emerges, which seeks to reconcile economic development with the environmental sustainability of the oceans and coastal areas. Its connection with the UN Sustainable Development Goals (SDGs), in particular SDG 14 - Life in Water, is a challenge due to possible competitions and conflicts between individual or industrial goals. The Blue Economy encompasses both established and emerging sectors, and is promoted as a strategy to protect the world's oceans and water resources. SDG 14 seeks to conserve and sustainably use the oceans, seas and marine resources, and has driven global efforts in this regard, such as creating marine protected areas and reducing marine pollution. Identifying the synergies between the Blue Economy and the SDGs is essential to harnessing the full potential of the ocean in a responsible and sustainable way.
D-Dimer: A Primer Biomarker in COVID-19
Authors: Chawda Niraj , Jain Suresh , Solanki Bhagirath , Sonkar Chetan , Arora Simran , Shah Sukruti , Tejani Vtrag , Chawla Jyot Kaur , Chaudhari Mukesh , Chaudhari Ravi , Bhattacharya Amal Kumar
Published: August 2023

Aim and Objective: To explore risk factors associated with mortality in COVID-19 patients and assess the use of D-dimer as a first line biomarker for disease severity and clinical outcome.

Materials and Methods: We retrospectively analysed the pathological and radiological characteristics of 2087 consecutive cases of COVID-19 in PSH, Vadodara, Gujarat, from March 2021 to July 2022. Graphically, MS-Excel with median values were used. Correlations of D-dimer upon admission with disease severity and in-hospital mortality were analysed accordingly. Data were collected in MS-Excel with median values.

Results: 2087 patients having positive RT-PCR and confirm diagnosis of Covid-19 were included upon hospital admission. Whereas, 65.78% (n= 1373) were male and 34.21% (n= 714) were female. Mean age was 52± 4 year. D-dimer level > 250 ng/mL at the time of hospital admission was the only fluctuating value accompanying with increased mortality [(95% CI), P = 0.025]. D-dimer elevation (≥250 ng/mL) was seen in 81.31% patients. Pericardial effusion and Deep vein thrombosis were ruled out in probability of thrombosis based on 2-D echo, X-ray chest and USG. This recommend that hyper-coagulopathy of the fibrin plays a significant role in the occurrence of thromboembolic complications with COVID-19 patients. D-dimer levels was crucially escalated with increasing severity of COVID-19 as determined by clinical improvement (within 5 days of hospital stay) and chest CT staging (CO-RADS score out of 25, P = 0.000). 319 patient were died during above said period and overall in-hospital mortality rate was 15.28%. Additionally, 6.08 % (n=127) patient were on BIPEP and all are died with 100% death ratio. Median D-dimer level in non-survivors (15.29%) was significantly higher than in survivors (84.71%, n = 1768, RR 24.69%). Median elevated D-dimer level was 600.5 ng/ml. Furthermore, the disease activity were higher in the overhead D-dimer level group demonstrated to have anticipating value in differentiating disease severity along with high ESR level and hs-CRP and the fibrinogen level was also upraised indicated seriousness of disease.

Conclusion: We concluded that D-dimer level was routinely uplifted in patients with COVID-19 disease. D-dimer levels match up with severity of the disease and are a significant definitive prognostic first line marker for in-hospital mortality for COVID-19 disease. Furthermore, a significant association between the high D-dimer level and severity of COVID-19 disease was noted among comorbid patients. Additionally, raced D-dimer level demonstrated with high ESR level and hs-CRP and the fibrinogen level indicated seriousness of disease in comorbid patients.
Optimization of Water Use Efficiency of Hydroponic Maize Fodder Production System under Different Microclimatic Conditions
Authors: Bhat Adarsha Gopalakrishna , Jinu A. , Sathian K. K.
Published: August 2023

Aims: Hydroponic method of producing fodder is an advanced technique which helps to achieve very high-water use efficiency (WUE). The main objective of the study was to optimize WUE by controlling the system and reducing the stress on the crops to give higher yield.

Study Design: The experiment employed a statistical design known as Completely Randomized Design Place and duration of the study: The experiment was carried out in the Precision Farming Development Centre (PFDC) building, Kelappaji College of Agricultural Engineering and Technology (KCAET), Tavanur during May and June 2021.

Methodology: Three different water application methods namely, mist (I1), micro sprinkler (I2), fogger (I3) was selected. Artificial light source of LED red (L1), LED blue (L2), LED red + blue (L3) and sunlight (L4) were considered for the study. Statistical analysis was conducted to understand the significance of different treatments used in the experiment in optimizing yield and WUE of the system.

Results: Highest yield was observed in treatment involving fogger irrigation and LED red + blue (2.11 kg/tray) with highest WUE (515.43 kg/m3) compared to other treatments. Seed to fodder ratio obtained was 1:6. Chemical analysis showed higher percentage of crude protein (13.56%) and crude fibre (12.59%) in this treatment. Higher growth of green fodder under artificial light source can be attributed to the continuous supply of energy compared to highly varying sunlight and also the uniform distribution of water by fogger irrigation which maintained favourable condition for fodder growth.

Conclusion: Results clearly indicated that growing green fodder with artificial light source (LED red + blue) and water supply with fogger can be recommended to farmers for achieving better growth of green fodder for domestic animals.
Effect of Varying Levels and Source of Slow-release Urea Fertilizers on Yield, Post Harvest Soil Nutrient Status and Economics of Wet Direct Seeded Rice (Oryza sativa L.)
Authors: Aruna K. , Tuti Mangal Deep , Rekha K. Bhanu , Surekha K. , Kumar R. Mahender
Published: August 2023

A field experiment was conducted at the research farm of ICAR-Indian Institute of Rice Research (IIRR), Hyderabad, Rajendranagar in kharif, 2022 to study the effect of varying levels and source of slow-release urea fertilizers on yield, post harvest soil nutrient status and economics of wet direct seeded rice. The experiment was laid out in a randomized block design with ten treatments consisting of nitrogen management practices and replicated thrice. The results revealed that 100% RDN (Recommended Dose of Nitrogen) (120 kg/ha) applied through silicon coated urea resulted in the highest grain yield (6249 kg/ha) and straw yield (7114 kg/ha). Post harvest soil nutrient status revealed that 125% recommended dose nitrogen (150 kg/ha) applied through silicon coated urea resulted in the highest soil available nitrogen. Similarly, the highest soil available nitrogen gain was recorded in the plots that received 125% silicon coated urea. Silicon coated urea applied @ 120 kg/ha ulimately fetched higher gross return of ₹. 1,42,964/ha, net returns ₹. 1,03,793 and benefit-cost ratio of 2.65. It can be concluded that RDN applied through silicon coated urea @ 120 kg/ha found to be a suitable alternative to neem coated urea in increasing the grain yield, soil fertility and profitability.
Oral Nonprescription Pain Medications for Adults
Authors: Vordenberg Sarah E.
Published: August 2023

This JAMA Patient Page describes the common oral nonprescription pain medications acetaminophen, aspirin, ibuprofen, and naproxen sodium.
Vitamin D Receptor Activation Attenuates Olanzapine‐Induced Dyslipidemia in Mice Through Alleviating Hepatic Endoplasmic Reticulum Stress
Authors: Dang Ruili , wang Jing , Tang Mimi , Han Wenxiu , Jiang Pei
Published: August 2023

The involvement of vitamin D (VD) signaling in atypical antipsychotics (AAPs)‐induced metabolic disturbances has been previously established. This study aims to elucidate the role of VD in maintaining endoplasmic reticulum (ER) homeostasis and its impact on AAPs‐induced metabolic adverse effects. Female C57BL/6 mice receive either calcitriol or vehicle one week prior to co‐treatment with olanzapine (OLZ) for an additional four weeks. Metabolic parameters, hepatic ER homeostasis, and the SREBPs pathway are assessed through biochemical assays and protein expression profiling. HepG2 cells are transfected with vitamin D receptor (VDR) siRNA for VDR knockdown. OLZ‐treated HepG2 cells are exposed to calcitriol to examine its effects on SREBPs and the unfolded protein response (UPR) pathways. VDR activation by calcitriol reduces OLZ‐induced hepatic ER stress, leading to decreased SREBPs activity and lipid accumulation. Conversely, the knockdown of VDR in HepG2 cells diminishes the protective effects of calcitriol against OLZ‐induced ER stress and SREBPs activation. This resulted in sustained UPR activation, elevated cleaved SREBPs levels, and increased lipid accumulation. These findings highlight an essential role of VDR signaling in the beneficial effects of VD on OLZ‐induced metabolic side effects. Targeting VDR to resolve ER stress is likely an applicable therapeutic strategy for AAPs‐induced metabolic disturbances.
NIR/Visible Light Double Beam Synergistically Enhanced the Emission of Triplet‐Triplet Annihilation Upconversion via Thermal Lensing Effect
Authors: Zhu Sijia , Wei Lingling , Sun Yujiao , Yang Cheng , Wu Wanhua
Published: August 2023

Stimuli‐responsive triplet‐triplet annihilation upcoversion (TTA‐UC) systems show additional application potentials in biological and environmental sensing besides the typical applications, such as improving the efficiency of solar‐powered devices. This work presents a double‐beam synergistically controlled TTA‐UC system that can increase the UC emission intensity by more than 6‐fold with the aid of the thermal lensing effect of an near‐infrared (NIR)‐absorbing solution in a double‐beam coupling system of visible/NIR light. The collimation effect of a divergent 532 nm laser beam, achieved through the concave lens effect of a Pdpc(OBu)8 solution under NIR irradiation, significantly increases the excitation power density of the UC system, which is responsible for the increment of UC emission intensity. The ON/OFF ratio of the TTA‐UC switching can be conveniently regulated by the output power of either the 532 nm laser or 721 nm laser, as well as the concentration and compounds of the photothermal lens effect solution. The visible/NIR stimuli‐responsive TTA‐UC system is applied to photolithography to increase both the speed and depth of the photo printing.