bluuebunny/crossref_metadata_2025 huggingface dataset:
Origins and Ends: Money and Power in and beyond Thucydides’ Peloponnesian War
Authors: Meadows Andrew
Published: January 2024

This article examines the disconnect between, on the one hand, the insistence on the part of multiple characters in Thucydides’ first book on the need for the Peloponnesians to invest in naval power to defeat Athens, and, on the other, the failure to act on this in the narrative of books 2–7. It then analyses the numismatic evidence for the way in which Sparta does then act upon this advice in the course of the Ionian War, and suggests that Thucydides’ view that this was done primarily with Persian support may be missing a (brief) Spartan attempt to create a fiscally self-supporting empire.
Fafner and the Rhinemaidens’ Treasure, Fifty Years On
Authors: Lewis David
Published: January 2024

This article discusses G.E.M. de Ste. Croix’s contentions about the effect of Helotage on Spartan foreign policy articulated in chapter IV of Origins of the Peloponnesian War, namely that Sparta’s Helot population was uniquely dangerous, constraining Sparta’s ability to send large numbers of citizen hoplites abroad lest it be exposed to the threat within. It shows that while certain arguments advanced by Ste. Croix are no longer tenable in light of subsequent research, others still stand up to critical scrutiny fifty years on; furthermore, other points neglected by Ste. Croix reinforce his overall claims.
Aspila pibooni (Lepidoptera: Tortricidae: Olethreutinae: Grapholitini), a peculiar new species from Thailand
Authors: PINKAEW NANTASAK
Published: January 2024

Aspila pibooni sp. nov. is described and illustrated from Thailand. The species is provisionally assigned to Aspila on the basis of morphological features of the male and female genitalia. Superficially, the new species resembles three Afrotropical species of Cydia (Grapholitini), all of which lack the distinctive coremata and a pair of short projections from the eight sternite that characterize the Grapholita group of genera to which Aspila belongs.
Wallachian Law as a Tool for Colonising Peripheral Areas: Case Study of the Sandomierz Forest in the 15th and 16th Centuries
Authors: Buniowski Jarosław
Published: January 2024

The uniqueness of Wallachian settlement in the territories of Poland was that it extended beyond its natural mountain and submontane zone. This resulted in the emergence of settlements founded under Wallachian law, including the Sandomierz Forest area. The aim of the article is to examine the economic activity of the residents of these settlements, which was conditioned by the environmental situation. One important problem addressed in this work is the question of reasons for the colonisation backwardness in this region, manifested in the slow pace of the progress of urbanisation, the limited scope of the money economy, and the late development of manorial demesnes, among other factors. These delayed and poorly discernible processes were followed by the evolution of the profile of Wallachian-law settlements, evident in the 16th century. The permeation of elements of Wallachian customs into agricultural settlements was an important adaptation element that has not been properly examined in the literature.
Holocaust Oral History Sources in the Yahad-In Unum Archive Collection (Based on Volhynia-Podolia General District Materials)
Authors: Mykhalchuk Roman Yuriyovych
Published: January 2024

The purpose of the article is to analyze the oral history collection of the Holocaust sources at the Yahad-In Unum scientific institution (Paris, France) on the example of the Nazi-occupied territories of the Volhynia-Podolia General District of Reichskommissariat Ukraine. The research methodology is based on the principles of historicism and scientific objectivity. Analysis of oral history sources is the main method of the research. Scientific novelty: For the first time in historiography, the oral history Holocaust sources of the Yahad-In Unum scientific institution were analyzed based on the example of the Volhynia-Podolia General District. The conclusions prove that the oral history sources of Yahad-In Unum have powerful potential for Holocaust studies. They have exclusive information that is not found in other sources. German and Soviet documents cannot fully shed light on Holocaust history. Instead, the stories of witnesses provide an opportunity to examine this topic in a multifaceted way.
From the Peripheries to the Centre via Asia: The Notion of European Identity in Polish and Serbian Travel Writings About Asia (1850s–1920s)
Authors: Ewertowski Tomasz
Published: January 2024

The paper focuses on various dimensions of European identity in Polish and Serbian travel writings about Asia in the period from the 1850s to the 1920s, examining several case studies that show how travellers often identified themselves as Europeans, but sometimes discussed various aspects of European identity and had many issues with this self-description. The analysis is based on a large corpus of Polish and Serbian travelogues, but works by Gustaw Olechowski, Karol Lanckoroński, Pavel Petrović, Jerzy Bandrowski, Milan Jovanović, Eugeniusz Romer, Jadwiga Marcinowska and Jelena Dimitrijević are scrutinised in detail. The following issues are discussed: assuming European identity, European identity and planetary consciousness, overcoming Orientalism, the periphery complex, reversed Orientalism and Occidentalism, patriotism, and identification with Asians.
On the Border of Worlds and on the Periphery of the Canon: The Place of the Dubrovnik Tradition in Serbian Literary History
Authors: Kubik Damian
Published: January 2024

The article attempts to discuss the status of Dubrovnik and its literary and cultural tradition in 19th- and 20th-century discourses in the frame of Serbian literary history. The starting point for the presented considerations will be the opinion of Jovan Deretić, who, perceiving the Dubrovnik tradition as “borderline”, referred to it as “a tradition of secondary importance” for the Serbian culture and literature system. In his opinion, it could not have become for the Serbs what it had become for Croatian literature, that is, “the central national tradition”. The text will discuss different points of view (both “internal” and “external”) on the “location” and importance of the city and its traditions in the context of ongoing discussions on the identity of Dubrovnik. The t exts of the n ineteenth-century authors (Đ. Nikolajević, I. Stojanović, L. Vojnović) and twentieth-century authors (J. Skerlić, P. Popović, M. Pantić) will be analyzed. The framework of the article will be determined by contemporary reflection on this subject (Z. Bojović, I. Arsić, S. Stipčević).
Wstęp do bloku tematycznego
Authors: Sajkowski Wojciech
Published: January 2024

Tekst stanowi wstęp do bloku tematycznego  numeru 12 "Colloquia Humanistica", który poświęcony jest relacjom centrum–peryferia i formowaniu się tożsamości zbiorowych i indywidualnych na Bałkanach i w Europie Środkowej. Większość wypowiedzi dotyczy przestrzeni Bałkanów i Europy Środkowej, ale niektóre poruszają zagadnienie  idei europejskości i Orientu w odniesieniu do innych przestrzeni.
Portret Artysty, czyli Adam Mickiewicz w optyce Penczo Sławejkowa. Odnaleziony List Władysław Mickiewicza
Authors: Sujecka Jolanta
Published: January 2024

Niniejszy tekst jest wprowadzeniem do odnalezionego w Muzeum Petko i Penczo Sławejkowów w Sofii Listu Władysława Mickiewicza (1838–1926) do Penczo Sławejkowa (1866–1912), bułgarskiego modernisty, wybitnego poety i krytyka. List odkrywa przed nami fragment korespondencji W. Mickiewicza i P. Sławejkowa, a zarazem zmusza do przywołania kontekstu bardzo bogatych kontaktów polsko-bułgarskich i wyjątkowo ciekawej percepcji całej twórczości Adama Mickiewicza (1798–1855), a zwłaszcza Pana Tadeusza i Dziadów w Bułgarii.
Design of Optoelectronic Transformer for Its Application in Traveling Wave Protection of Power Grid
Authors: Xu Meng , Li Xuewu
Published: January 2024

As an important foundational link of the power system, the reliable measurement and accurate data of the metering module are the important foundation and support for energy metering. As a new type of optoelectronic current transformer, magneto-optical crystal-based optoelectronic current
transformer effectively avoids the defects of traditional electromagnetic current transformers and becomes an ideal equipment for measurement in power systems. This paper proposes an improvement method to enhance the temperature stability of optoelectronic current transformers, using a magneto-optical
crystal sensor head based on Faraday effect to limit the fiber length to within 140 m. It considers the influence of a uniform temperature field on magneto-optical crystal materials to process data reasonably to ensure normal incidence of the incident beam. The magneto-optical crystal material
in the non-uniform temperature field has non-uniform deformation due to thermal expansion and cold contraction. Here, a Karamay No. 45 cooling oil is used for filling and sealing. In the experiment, the temperature stability of the current transformer is tested. Firstly, the wiring method
is designed. Then, the corresponding test system is designed. After improvement, there is no drift phenomenon in the ratio difference and angle difference of all points of the photoelectric current transformer within the testing temperature range, and the error difference is stable. The principle
of identifying faults within the area is elaborated, and a directional longitudinal traveling wave protection method for direct-current transmission lines is designed based on the differential output characteristics of the designed photoelectric transformer. Through experiments, the transformer
in this design can effectively identify potential traveling wave fault types and fault phases.
Revaluation Method of Sensor Power Supply
Authors: Chen Demin , Zhang Xi
Published: January 2024

This study proposes an approach for wireless sensor power supply voltage early warning using statistical models. Experimental and statistical analysis of electrical parameters and battery discharge characteristics were conducted to establish a reliable evaluation process. A linear regression
model was employed to analyze and fit known temperature and voltage data, establishing a relationship model between voltage and temperature and using it to predict unknown voltage threshold data. This solves the problem of the inability to real-time predict the warning voltage threshold of
wireless sensors as the actual working temperature changes and ensures their reliability. The results of experiments and statistical analysis demonstrate the effectiveness and accuracy of this method. Compared to the traditional method of using fixed voltage thresholds for warning, the proposed
method offers a practical solution that can timely address the issue of low power supply voltage in wireless sensor networks.
Effect of Quercetin on Fecal Syndecan-2 Gene Methylation Levels in Patients with Colorectal Cancer and Its Potential Mechanism of Action
Authors: Li Nanyang , Zhang Xuejun , Li Chunmei , Wang Feng , Li Lian , Liang Jingjing , Wang Fengqiang
Published: January 2024

Colorectal cancer (CRC) is a relatively common malignant tumor of the digestive system. In this research, the impact of quercetin (Que) on fecal syndecan-2 (SDC2) gene methylation levels in CRC patients and its potential mechanisms of action were analyzed. Retrospective analysis was
conducted on data from 56 CRC patients admitted to our outpatient department. The methylation status of SDC2 in fecal samples and the sensitivity and specificity of fecal SDC2 gene detection were analyzed. Subsequently, MTT assay was performed to assess the impact of Que on cell viability
of SW480 cells during the growth phase. The blank control consisted of 200 μL of L-15 medium, the solvent control group consisted of 200 μL of L-15 medium+150 μL of dimethyl sulfoxide (DMSO), and the experimental group consisted of 200 μL of L-15 medium+different
concentrations of Que (5, 10, 20, 40, 80, 120 μmol/L). After SW480 cells were treated with various concentrations of Que, protein expression (EP) levels of C-Myc, B-cell lymphoma (Bcl)-2, phosphorylated STAT3 (p-STAT3), and interleukin (IL)-6 were determined by qRT-PCR and Western
blot. The single-gene detection of SDC2 in fecal samples yielded an area under the curve (AUC) of 0.763 (95% confidence interval (CI): 0.623–0.876). As the concentration of Que increased, the OD values decreased. Various concentrations of Que exhibited varying inhibitory effects on SW480
cell proliferation (CP) at different time intervals, with the OD values at 72 h being superior to those at 48 h and 24 h. The OD values at 48 h were superior to those at 24 h, indicating a significant enhancement of SW480 proliferation with prolonged time. As the treatment concentration increased,
the cell viability gradually decreased. Que at concentrations ranging from 20 to 160 μmol/L showed a notable inhibition of SW480 CP. With increasing concentrations of Que, protein levels of C-Myc, Bcl-2, p-STAT3, and IL-6 decreased gradually. In summary, Que can inhibit the EP of
inflammatory factors in CRC patients, suppress tumor CP by downregulating protein levels of C-Myc, Bcl-2, p-STAT3, and IL-6, and thus exert an anti-CRC effect.
Gefitinib Induces Apoptosis of Gastric Cancer Cells by Promoting Glutaminolysis Through the MEK/ERK Signaling Pathway
Authors: Peng Zhiyang , Liu Yahui , Zheng Yongbing , Zhou Rui
Published: January 2024

We aimed to investigate the effect of gefitinib on the proliferation and apoptosis of gastric cancer (GC) cells through the MEK/ERK signaling pathway. The GC cell line NCI-N87 was cultured in vitro and divided into a control group and a gefitinib group. Cell viability for NCI-N87
was determined using the MTT test. The amount of apoptosis in NCI-N87 cells was measured using flow cytometry. Real-time quantitative PCR was used to measure GDH1 mRNA expression in NCI-N87 cells. P-MEK1/2, MEK1/2, P-ERK1/2, and ERK1/2 protein expression levels in NCI-N87 cells were determined
using Western blotting. An assay kit for measuring glutamine was used to determine the intracellular glutamine concentration of NCI-N87 cells. The proliferative activity of NCI-N87 cells was significantly inhibited in the gefitinib group compared to the control group, along with the transcription
level of GDH1, intracellular glutamine content, intracellular glutamine content reduction, and p-MEK1/2 and p-ERK1/2 protein expression levels. Gefitinib inhibits proliferation and promotes apoptosis in the GC cell line NCI-N87 by downregulating the EGFR/MEK/ERK signaling pathway. Mechanistically,
it is achieved by promoting the expression of GDH1 to promote glutaminolysis in NCI-N87 cells.
Clinical Characteristics and Endometrial Lesions of Postmenopausal Patients with Abnormal Uterine Bleeding
Authors: Hu Jianfang , Fan Lilin , Hu Linyi , Shen Haiyan
Published: January 2024

This study delves into factors linked to abnormal uterine bleeding and endometrial issues during perimenopause. Analyzing clinical data from 333 perimenopausal patients with abnormal uterine bleeding, we identified key variables influencing endometrial lesions. Of these cases, 26.1%
exhibited normal endometrium, while 63.1% had benign lesions (including polyps, leiomyomas, and hyperplasias), and 10.5% presented with endometrial cancer. Single-factor analysis revealed correlations between factors like age, BMI, parity, hypertension history, IUD usage, family cancer history,
bleeding duration, endometrial characteristics, and tumor markers, and distinct endometrial changes (P <0.05). Multivariate analysis emphasized the significance of age groups (40–45, 45–50, 50–55 years) and endometrial thickness on benign and malignant lesions (P
<0.05). As perimenopausal abnormal uterine bleeding rises, early detection of these factors and the establishment of an effective diagnostic and treatment framework will greatly enhance the well-being of perimenopausal women.
Intramucosal Extent as a Marker for Advanced Disease and Survival in Gallbladder Adenocarcinoma
Authors: Naples Robert , Perlmutter Breanna C. , Lu Haiyan , Allende Daniela , Tu Chao , Hitawala Asif , Chadalavada Pravallika , Padbidri Vinay , Haddad Abdo , Simon Robert , Walsh R. Matthew , Augustin Toms
Published: January 2024

Background

Gallbladder cancer (GBC) is the most common biliary tract malignancy and has a poor prognosis. The clinical significance of focal vs diffuse GBC remains unclear.

Methods

A retrospective review was conducted on all patients with non-metastatic GBC at a quaternary care center. Pathology was reviewed, and gallbladder cancer pattern was defined based on the extent of mucosal involvement; “diffuse” if the tumor was multicentric or “focal” if the tumor was only in a single location. Patients undergoing liver resection and portal lymphadenectomy were considered to have definitive surgery. The primary outcome was overall survival and assessed by Kaplan-Meier curves.

Results

63 patients met study criteria with 32 (50.7%) having diffuse cancer. No difference was observed in utilization of definitive surgery between the groups (14 [43.8%] with focal and 12 [38.7%] with diffuse, P = .88). Lymphovascular invasion ( P = .04) and higher nodal stage ( P = .04) were more common with diffuse GBC. Median overall survival was significantly improved in those with focal cancer (5.1 vs 1.2 years, P = .02). Although not statistically significant, this difference in overall survival persisted in patients who underwent definitive surgery (4.3 vs 2.4 years, P = .70).

Discussion

Patients with diffuse involvement of the gallbladder mucosa likely represent a subset with aggressive biology and worse overall survival compared to focal disease. These findings may aid surgeons in subsequent surgical and medical decision-making for patients with GBC.
Application of a Human Factors and Systems Engineering Approach to Explore Care Transitions of Sepsis Survivors From Hospital to Home Health Care
Authors: Oh Sungho , Sang Elaine , Stawnychy Michael A. , Garren Patrik , You Sang Bin , O’Connor Melissa , Hirschman Karen B. , Hodgson Nancy , Cranston Teresa , Jablonski Juliane , O’Brien Karen , Newcomb Michael , Spahr Melissa , Bowles Kathryn H.
Published: January 2024

Study Aim

This study aims to describe the transition-in-care work process for sepsis survivors going from hospitals to home health care (HHC) and identify facilitators and barriers to enable practice change and safe care transitions using a human factors and systems engineering approach.

Background

Despite high readmission risk for sepsis survivors, the transition-in-care work process from hospitals to HHC has not been described.

Methods

We analyzed semi-structured needs assessment interviews with 24 stakeholders involved in transitioning sepsis survivors from two hospitals and one affiliated HHC agency participating in the parent implementation science study, I-TRANSFER. The qualitative data analysis was guided by the Systems Engineering Initiative for Patient Safety (SEIPS) framework to describe the work process and identify work system elements.

Results

We identified 31 tasks characterized as decision making, patient education, communication, information, documentation, and scheduling tasks. Technological and organizational facilitators lacked in HHC compared to the hospitals. Person and organization elements in HHC had the most barriers but few facilitators. Additionally, we identified specific task barriers that could hinder sepsis information transfer from hospitals to HHC.

Conclusion

This study explored the complex transition-in-care work processes for sepsis survivors going from hospitals to HHC. We identified barriers, facilitators, and critical areas for improvement to enable implementation and ensure safe care transitions. A key finding was the sepsis information transfer deficit, highlighting a critical issue for future study.

Application

We recommend using the SEIPS framework to explore complex healthcare work processes before the implementation of evidence-based interventions.
Similar and different? A cross-cultural comparison of the prevalence, course of and factors associated with suicidal thoughts and behaviors in first-episode psychosis in Chennai, India and Montreal, Canada
Authors: Sicotte Roxanne , Abdel-Baki Amal , Mohan Greeshma , Rabouin Daniel , Malla Ashok , Padmavati Ramachandran , Moro Laura , Joober Ridha , Rangaswamy Thara , Iyer Srividya N.
Published: January 2024

Background:

Data from high-income countries (HICs) show a high risk of suicidal thoughts and behaviors (STBs) in first-episode psychosis (FEP). It is unknown, however, whether rates and associated factors differ in low- and middle-income countries (LMICs).

Aims:

We therefore aimed to compare the 2-year course of STBs and associated factors in persons with FEP treated in two similarly structured early intervention services in Chennai, India and Montreal, Canada.

Method:

To ensure fit to the data that included persons without STBs and with varying STBs’ severity, a hurdle model was conducted by site, including known predictors of STBs. The 2-year evolution of STBs was compared by site with mixed-effects ordered logistic regression.

Results:

The study included 333 FEP patients (168 in Chennai, 165 in Montreal). A significant decrease in STBs was observed at both sites (OR = 0.87; 95% CI [0.84, 0.90]), with the greatest decline in the first 2 months of follow-up. Although three Chennai women died by suicide in the first 4 months (none in Montreal), Chennai patients had a lower risk of STBs over follow-up (OR = 0.44; 95% CI [0.23, 0.81]). Some factors (depression, history of suicide attempts) were consistently associated with STBs across contexts, while others (gender, history of suicidal ideation, relationship status) were associated at only one of the two sites.

Conclusions:

This is the first study to compare STBs in FEP between two distinct geo-sociocultural contexts (an HIC and an LMIC). At both sites, STBs reduced after treatment initiation, suggesting that early intervention reduces STBs across contexts. At both sites, for some patients, STBs persisted or first appeared during follow-up, indicating need for suicide prevention throughout follow-up. Our study demonstrates contextual variations in rates and factors associated with STBs. This has implications for tailoring suicide prevention and makes the case for more research on STBs in FEP in diverse contexts.
Outcomes of psychosocial interventions for homeless individuals with mental illness: A systematic review
Authors: Roy Roniyamol , Raman K Janaki , Raj E Aravind , Varambally Shivarama
Published: January 2024

Background:

Homelessness creates a significant social and economic burden in the society. Homelessness and mental illness are two interconnected social issues that poses challenges to individuals and communities across the globe. This systematic review aims to synthesize the existing literature on interventions for the homeless persons with mental illness.

Objectives:

To systematically review the existing literature on psychosocial interventions for homeless persons with mental illness.

Search methods:

Five databases including PubMed, ProQuest, Cochrane Library, OVID, and Google Scholar were searched using homelessness, psychosocial interventions, mental ill, residential mental health facility, and case management for experimental studies published from January 2000 to December 2022.

Study selection:

Abstract review was conducted for the screened studies, and full-text review was done for studies which met inclusion exclusion criteria.

Data extraction and analysis:

Among the 6,387 studies screened 20 studies were selected which fulfilled inclusion criteria. The full text review yielded data of 12,174 homeless persons with mental illness who undergone intervention.

Results:

The major psychosocial interventions found including critical time intervention, case management, housing support intervention, assertive community treatment, and life skills training. These interventions were helpful in sustaining housing stability, preventing relapse, reducing hospitalizations, and improving quality of life of the homeless persons with mental illness.

Conclusion:

Targeted and integrated interventions addressing homelessness and mental illness are required to tackle the social problems of homelessness and mental illness. Further research is required to explore the most effective strategies that address homelessness and mental illness.
Daily Cannabis Use: Do Impulsivity and Sensation Seeking Predict Negative Cannabis Related Consequences?
Authors: Parnes Jamie E. , Tyskiewicz Alexander J. , Prince Mark A. , Conner Bradley T.
Published: January 2024

Objective

Cannabis use can result in negative cannabis-related consequences (NCRC), particularly among individuals high in impulsivity and sensation seeking. Continued research is necessary to determine if these associations generalize to community adults with daily legal cannabis use. We hypothesized that impulsivity and sensation seeking would positively predict NCRC.

Method

Community adults ( N = 51) participated in a study measuring personality, cannabis use, and related outcomes, as part of a larger study. Two multiple regression models predicting NCRC were conducted: one for impulsivity facets and one for sensation seeking facets.

Results

Positive urgency was significantly negatively associated with NCRC. Risk seeking was significantly positively associated with NCRC. All other personality facets were not significantly associated with NCRC.

Conclusions

Associations between some personality facets and NCRC may differ among adults with daily legal cannabis use. Future research should continue to explore unique personality associations related to NCRC among individuals with daily use.
Diverging mobility situations in Greater Mexico City: Exploring the factors behind the mobility situations of public transport commuters
Authors: López-García David
Published: January 2024

This article investigates the factors behind the likelihood of experiencing a specific type of mobility situation. The case of commuting by public transport in Greater Mexico City is analysed. A one-way ANOVA with post-hoc procedures and three multinomial logistic regression models are used to assess the extent to which transport-, land use- or socio-economic-related variables influence the likelihood of experiencing a specific mobility situation. The results show that the mobility situations of workers are primarily influenced by the socio-economic characteristics of commuters, followed by land-use patterns and the availability of transport systems, respectively. This means that in addition to transport-related policies, reducing commuting disparities in urban regions will require policies able to reduce socio-economic inequalities and influence the urban structure.
The multiple services of hydropower plants in the context of sustainable electric sector in Brazil
Authors: Damazio Jorge M. , dos Santos Marco Aurélio
Published: January 2024

At the worldwide level, the hydroelectricity corresponds to 54% of all renewable electricity, 15% of total electricity generated and only 3% of all total primary energy. In Brazil, hydropower produces 74% of all renewable electricity, 57% of electrical energy and 11% of all total primary energy (EPE, 2023). As all over the world, the construction and operation of large artificial reservoirs until the mid-twentieth century was seen in Brazil by government and by the general public as important infrastructure investment for economic development and improvement of well-being. Nowdays, investments in hydropower plants are re-gaining importance given not only its ability in supporting the transition of the electricity grid to get rid of dependence on fossil fuels but also in the provision of numerous other services. In particular, Brazilian hydropower plants contribute to multiple water resources management services such as flood and drought control, groundwater stabilization, water quality management, river navigation, irrigation, leisure and tourism and aquaculture around the country. The article discusses the multiple services provided to society by hydroelectric power plants within the context of sustainability in Brazil.
Diminishing returns of growth? Economic performance, needs satisfaction and ecological impacts of OECD welfare states
Authors: Paulsson Alexander , Koch Max , Fritz Martin
Published: January 2024

The environmental crisis, increased inequality and an aging population are likely to increase the demand for welfare services in the OECD countries. Economic growth has long been seen as a solution to these problems. However, this is no longer the case. Very few countries have managed to decouple economic performance from ecological footprints and greenhouse gas emissions. Even where this has been achieved, the rates of emission-decline are too slow to match the Paris climate targets. Consequently, interdisciplinary research is key to probe how welfare systems may cope with these challenges, and how welfare provision and economic growth may be decoupled. By drawing on the basic human needs approach and a unique set of data, we explore the social and ecological performances of OECD countries relative to their economic performances. While high-income countries display diminishing welfare returns as economic performance is not improving the satisfaction of health-related needs, the lower-income countries might yield significant surplus if moving to the level of moderate-income countries. However, the satisfaction of autonomy-related needs is so far strongly coupled to economic performance and thus much harder to achieve in an ecologically sustainable way.
Bordering social reproduction: The welfare/immigration regimes of Quebec and Ontario in Canada
Authors: CÔTÉ-BOUCHER KARINE , BRAEDLEY SUSAN
Published: January 2024

This article makes three crucial, related arguments. First, most European analyses of immigration and social welfare fail to consider how these policies intersect to shape the social reproduction of populations, instead sticking to notions of welfare chauvinism, social citizenship, and deservingness. Second, welfare/immigration analyses are usually set at the national level, but subnational comparisons can challenge tidy welfare state regime categorizations, revealing both nuance and policy opportunities. Third, a focus on social reproduction regimes that includes welfare and immigration policies reveals how jurisdictions border the extraction of social reproductive labour, with impacts on who gets in and under which conditions, and on the distribution of paid and unpaid social reproductive work within immigrant and established families in Canada. Developing our feminist border analysis, we illustrate our approach through a comparative analysis of Quebec and Ontario to show how social reproductive borders extract care labour and from whom, under diverging policy regimes.
Theology and politics in Northeast India: Interpreters in an evolving intellectual terrain
Authors: Lalruatkima
Published: January 2024

Theology from the northeast of India draws heavily from the cultural capital of its constituents. As an unintended consequence, tribal theology invokes a past that renders its theological discourse as rather distant from the evolving political economy of faith communities in the northeast of India. A turn from legislating what tribal theology is to interpreting the politics of tribal communities provides an important intervention. Interpreting politics as significations and management inevitably necessitates self-reflexivity to render an honest reading of theology in the northeast of India.
Perioperative oxygenation impairment related to type a aortic dissection
Authors: Liu Qindong , Guan Yulong , Yang Xiaofang , Jiang Yu , Hei Feilong
Published: January 2024

Type A aortic dissection (TAAD) is a life-threatening disease with high mortality and poor prognosis, usually treated by surgery. There are many complications in its perioperative period, one of which is oxygenation impairment (OI). As a common complication of TAAD, OI usually occurs throughout the perioperative period of TAAD and requires prolonged mechanical ventilation (MV) and other supportive measures. The purpose of this article is to review the risk factors, mechanisms, and treatments of type A aortic dissection-related oxygenation impairment (TAAD-OI) so as to improve clinicians’ knowledge about it. Among risk factors, elevated body mass index (BMI), prolonged extracorporeal circulation (ECC) duration, higher inflammatory cells and stored blood transfusion stand out. A reduced occurrence of TAAD-OI can be achieved by controlling these risk factors such as suppressing inflammatory response by drugs. As for its mechanism, it is currently believed that inflammatory signaling pathways play a major role in this process, including the HMGB1/RAGE signaling pathway, gut-lung axis and macrophage, which have been gradually explored and are expected to provide evidences revealing the specific mechanism of TAAD-OI. Numerous treatments have been investigated for TAAD-OI, such as nitric oxide (NO), continuous pulmonary perfusion/inflation, ulinastatin and sivelestat sodium, immunomodulation intervention and mechanical support. However, these measures are all aimed at postoperative TAAD-OI, and not all of the therapies have shown satisfactory effects. Treatments for preoperative TAAD-OI are not currently available because it is difficult to correct OI without correcting the dissection. Therefore, the best solution for preoperative TAAD-OI is to operate as soon as possible. At present, there is no specific method for clinical application, and it relies more on the experience of clinicians or learns from treatments of other diseases related to oxygenation disorders. More efforts should be made to understand its pathogenesis to better improve its treatments in the future.
Dabigatran pharmacokinetic-pharmacodynamic in sheep: Informing dose for anticoagulation during cardiopulmonary bypass
Authors: Eaton Michael P , Nadtochiy Sergiy M , Stefanos Tatsiana , Anderson Brian J
Published: January 2024

Background

The effect of the anticoagulant, dabigatran, and its antagonist, idarucizumab, on coagulation remains poorly quantified. There are few pharmacokinetic-pharmacodynamic data available to determine dabigatran dose in humans or animals undergoing cardiopulmonary bypass.

Methods

Five sheep were given intravenous dabigatran 4 mg/kg. Blood samples were collected for thromboelastometric reaction time (R-time) and drug assay at 5, 15, 30, 60, 120, 240, 480 min, and 24 h. Plasma dabigatran concentrations and R-times were analyzed using an integrated pharmacokinetic-pharmacodynamic model using non-linear mixed effects. The impact of idarucizumab 15 mg/kg administered 120 min after dabigatran 4 mg/kg and its effect on R-time was observed.

Results

A 2-compartment model described dabigatran pharmacokinetics with a clearance (CL 0.0453 L/min/70 kg), intercompartment clearance (Q 0.268 L/min/70 kg), central volume of distribution (V1 2.94 L/70 kg), peripheral volume of distribution (V2 9.51 L/70 kg). The effect compartment model estimates for a sigmoid EMAX model using Reaction time had an effect site concentration (Ce50 64.2 mg/L) eliciting half of the maximal effect (EMAX 180 min). The plasma-effect compartment equilibration half time (T1/2keo) was 1.04 min. Idarucizumab 15 mg/kg reduced R-time by approximately 5 min.

Conclusions

Dabigatran reversibly binds to the active site on the thrombin molecule, preventing activation of coagulation factors. The pharmacologic target concentration strategy uses pharmacokinetic-pharmacodynamic information to inform dose. A loading dose of dabigatran 0.25 mg/kg followed by a maintenance infusion of dabigatran 0.0175 mg/kg/min for 30 min and a subsequent infusion dabigatran 0.0075 mg/kg/min achieves a steady state target concentration of 5 mg/L in a sheep model.
IT’s a matter of trust: Literature reviews and analyses of human trust in information technology
Authors: Lacity Mary C , Schuetz Sebastian W , Kuai Le , Steelman Zachary R
Published: January 2024

Trust is one of the most important constructs for understanding the adoption of information technologies (IT). In this paper, we review and analyze two literatures on the construct of human trust in IT artifacts and in the entities that source, operate, and govern IT. The first literature review focuses on defining of the construct of trust across a range of disciplines. Our analysis of this literature identified 13 assumptions about the nature of trust. The assumptions illustrate the complexities of human trust. The second literature review focused on 214 empirical studies of the construct of trust published in the AIS Senior Scholars’ Basket of Eight journals. We analyze this literature to identify IS scholar’s most common assessments of trust from qualitative studies and most common measures of trust from quantitative studies. As a cumulative body of knowledge, IS scholars have deeply examined the multidimensional aspect of trust by examining different types of trust, including affective trust, cognitive trust, institutional trust, instrumental trust, intrinsic trust, knowledge-based trust, relational trust, swift trust, disposition to trust, trusting beliefs, and more. IS scholars have also extensively examined the assumption that trust is dynamic, as evidenced by the many qualitative papers that examined trust as a process. Our review also finds that IS scholars have conducted extensive research examining trust in Web2 technologies, which are characterized by centralized applications and centralized governance. While the IS scholarly community has established a substantial tradition around the construct of trust, there is still interesting work to be done. With recent releases of open generative AI and with the rise of Web3 technologies like blockchains that purport to be “trustless,” the construct of trust in IT needs to be re-examined in these emerging contexts. We also encourage more research on trust in bi-directional relationships, on the limits of transitive trust, and on the construct of distrust.
International Systematic Review of Utility Values Associated with Cardiovascular Disease and Reflections on Selecting Evidence for a UK Decision-Analytic Model
Authors: Hainsworth Rob , Thompson Alexander J. , Guthrie Bruce , Payne Katherine , Rogers Gabriel
Published: January 2024

Purpose

Evaluating interventions for cardiovascular disease (CVD) requires estimates of its effect on utility. We aimed to 1) systematically review utility estimates for CVDs published since 2013 and 2) critically appraise UK-relevant estimates and calculate corresponding baseline utility multipliers.

Methods

We searched MEDLINE and Embase (April 22, 2021) using CVD and utility terms. We screened results for primary studies reporting utility distributions for people with experience of heart failure, myocardial infarction, peripheral arterial disease, stable angina, stroke, transient ischemic attack, or unstable angina. We extracted characteristics from studies included. For UK estimates based on the EuroQoL 5-dimension (EQ-5D) measure, we assessed risk of bias and applicability to a decision-analytic model, pooled arms/time points as appropriate, and estimated baseline utility multipliers using predicted utility for age- and sex- matched populations without CVD. We sought utility sources from directly applicable studies with low risk of bias, prioritizing plausibility of severity ordering in our base-case model and highest population ascertainment in a sensitivity analysis.

Results

Most of the 403 studies identified used EQ-5D ( n = 217) and most assessed Organisation for Economic Co-operation and Development populations ( n = 262), although measures and countries varied widely. UK studies using EQ-5D ( n = 29) produced very heterogeneous baseline utility multipliers for each type of CVD, precluding meta-analysis and implying different possible severity orderings. We could find sources that provided a plausible ordering of utilities while adequately representing health states.

Conclusions

We cataloged international CVD utility estimates and calculated UK-relevant baseline utility multipliers. Modelers should consider unreported sources of heterogeneity, such as population differences, when selecting utility evidence from reviews.

Highlights

Published systematic reviews have summarized estimates of utility associated with cardiovascular disease published up to 2013. We 1) reviewed utility estimates for 7 types of cardiovascular disease published since 2013, 2) critically appraised UK-relevant studies, and 3) estimated the effect of each cardiovascular disease on baseline utility. Our review 1) recommends a consistent and reliable set of baseline utility multipliers for 7 types of cardiovascular disease and 2) provides systematically identified reference information for researchers seeking utility evidence for their own context.
Association of radiocephalic arteriovenous anatomical markers with post-angioplasty blood flow volume
Authors: Tanyeri Ahmet
Published: January 2024

Background

Doppler ultrasound (DUS) blood volume flow (VF) calculation is the most reliable method for demonstrating the success of endovascular treatment of dysfunctional radiocephalic arteriovenous fistula (AVF). Due to the difficulty of this method for the interventionalist, VF-correlated markers are required during the procedure.

Purpose

To investigate the relationship between intraprocedural anatomical markers (AMs) and changes in VF induced by percutaneous transluminal angioplasty (PTA).

Material and Methods

The study included 56 patients with dysfunctional radiocephalic AVF who underwent PTA between September 2020 and 2022. The VF of all patients was measured using DUS before and 1 h after PTA. AMs were determined from 10 images, five before and five after balloon angioplasty.

Results

The mean post-PTA VF was 637 ± 277 mL/min compared to baseline (151 ± 107 mL/min). Before and after balloon angioplasty, vein diameter (VD), artery diameter (AD), stenosis minimum luminal diameter (MLD), stenosis percentage (SP), and VF values were statistically significant ( P = 0.001). Spearman’s correlation analysis showed a positive strong linear relationship between VF and MLD ( rs = 0.850, P <0.001), and a negative strong linear relationship between VF and SP ( rs = 0.815). Receiver operating characteristic curve analysis showed that the sensitivity and specificity for VF ≥400 mL/min at cutoffs of SP <50% and MLD >2.5 mm were 81% and 82%, and 81% and 90%, respectively.

Conclusion

Among the AMs readily available during PTA, first MLD and then SP provided satisfactory results in predicting VF.
Eyes meet, hands greet: The art of timing in social interactions
Authors: Kingstone Alan , Walker Esther , Amin Shahrazad , Bischof Walter F.
Published: January 2024

Shaking hands is a fundamental form of social interaction. The current study used high-definition cameras during a university graduation ceremony to examine the temporal sequencing of eye contact and shaking hands. Analyses revealed that mutual gaze always preceded shaking hands. A follow up investigation manipulated gaze when shaking hands, and found that participants take significantly longer to accept a handshake when an outstretched hand precedes eye contact. These findings demonstrate that the timing between a person's gaze and their offer to shake hands is critical to how their action is interpreted.
A learning-centred computational fluid dynamics course for undergraduate engineering students
Authors: Li Xiangdong , Cheung Sherman CP
Published: January 2024

The great demands for computational fluid dynamics (CFD) practitioners in industry have motivated universities to integrate CFD courses into undergraduate curricula. This article introduces a learning-centred CFD course that aims to train critical users of commercial CFD codes. The main features of the course include a project-based approach to learning and assessment-guided learning activities, both scaffolded by technologies. The implementation of the course is informed by contemporary pedagogical theories that encourage students to have the ownership of their own learning and constructively build their knowledge in an inclusive and supportive learning environment. The students upon completing the course have developed a conceptual understanding of the CFD principles and the importance of performing CFD simulations in a critical way, making them ready for more advanced CFD learning and practices. Course evaluation based on feedback from various sources demonstrates that the learning-centred approach is the key to the success of the course.
Guidelines on assigning the subjects of theses and dissertations in repositories
Authors: Fujita Mariângela Spotti Lopes , Panuto Jessica Cristina
Published: January 2024

This study aims to investigate how Brazilian institutional repositories guide subject representation in the self-archiving of their information resources. As a method, an exploratory and qualitative study was carried out with the application of an electronic exploratory analysis of repositories and an analysis of transcripts of thesis and dissertation authors’ Individual Verbal Protocols during self-archiving. The analysis of the results in the Brazilian university repository sample shows that 10 have a self-archiving policy and five include guidance to the author on subject representation and metadata quality. The transcription analysis of the authors’ Individual Verbal Protocols reveals that all authors consider keywords important for content representation. The investigation concludes that the self-archiving process is fundamental for the dissemination of scientific information and wide access to the community.
Bibliometric Analysis of Environmental Management Literature in Aviation
Authors: Uzgör Mustafa , Selahattin Ateş Savaş , Kafalı Haşim
Published: January 2024

The increasing interest in environmentally sustainable aviation has led to the topic becoming popular in aviation management literature. However, to the best of our knowledge, no research analyzes aviation environmental management (AEM) literature in a comprehensive manner. This study aims to bridge this gap by conducting a retrospective examination of environmental sustainability studies in literature using the bibliometric analysis method. Identifying potentially important gaps and drawing a comprehensive picture of the dynamics and the state of the literature is an important task to drive future studies in the field. Results drawn from 511 publications indexed in the Web of Science (WoS) database indicate a recent and rapid growth in the literature. Greenhouse gas emissions and noise emissions are dominant research themes while waste and water management topics are not well established. Studies investigating alternative fuels, emission mitigation strategies, energy conservation, and noise abatement are prevalent in the literature.