bluuebunny/crossref_metadata_2025 huggingface dataset:
Compensation for moral damage to the employee caused by a workplace accident or an occupational disease (example of Turkey)
Authors: Panchenko Olha
Published: May 2023

Workplace accidents not only threaten the lives of workers and damage the human capital of employers, but also increase the social costs of the State. Almost all industrialized countries have introduced laws and regulations to prevent industrial accidents and occupational diseases to reduce the cost of recovering such losses. Within the framework of this article, we turned to the example of Turkey, since this issue is regulated in sufficient detail in the legislation of this State. It has been established, that the main condition for an accident to be considered workplace accident is that the employer supervises the employee. Therefore, it is not necessary that the event takes place at the time when the employee is at the workplace or as a result of the employer’s wrongful actions. The definitions of the concepts of accident at work and occupational disease, enshrined in Social Insurance and Universal Health Insurance Law have been considered. According to the provisions of the same Law, the employer is obliged to report an accident or occupational disease to the head of the Social Security Institution (SSI) within 3 days after the event. It has been studied what types of benefits the victim can expect within social insurance. It has been determined, that claims for compensation for material and moral damage, as well as compensation for deprivation of material support as a result of an accident at work or occupational disease, are brought directly to the employer, since these types of damage are not compensated under social insurance. The conditions, the fulfillment of which is necessary to bring the employer to responsibility, have been investigated. The procedure for calculating moral compensation is not enshrined at the legislative level, but it was formed by the relevant practice of the Supreme Court. The factors that the court takes into account when determining the amount of compensation have been studied
Design Optimization of the Skylight for Daylighting and Energy Performance Using NSGA-II
Authors:   Department of Architecture, Tarbiat Modares University, Tehran, Iran, Fakhr Bahereh Vojdani , Mahdavinejad Mohammadjavad ,   Department of Architecture, Tarbiat Modares University, Tehran, Iran, Rahbar Morteza ,   Computational Design & Digital Fabrication, Iran University of Science and Technology, Tehran, Iran, Dabaj Banafsheh ,   Energy and Architecture, Pars University of Architecture and Art, Tehran, Iran
Published: May 2023

In terms of sustainable design, lateral windows and skylights are important. Daylighting has become a vital component in office buildings because it increases occupants' productivity, well-being, and energy savings via windows and skylights. As a result, various factors have an impact on achieving Useful Daylight Illuminance (UDI) and lowering overheating and glare discomfort. First the merits of the skylight and the window are compared in this study. Second, this study constructs an intelligent optimization method NSGA-II based on Pareto front approaches that allows low energy use of the office building while maintaining excellent thermal and lighting comfort for the inhabitants. Finally, all optimum solutions look at Daylight Glare Probability (DGP) for visual comfort. Isfahan, Iran (32° N, 51° E) as a hot and dry climatic condition, is selected for the simulation. A variety of geometries with different parameters, were applied to meet the goal. Among the different cases, the optimization’s findings highlight the pyramidal design with the highest aperture on the floor. It's best for a hot, dry area and a space with a square or rectangular form. The degree of glare in all ideal geometries, on the other hand, was reasonable—furthermore, these findings aid designers in selecting the appropriate window for the building's form and environment.
Moisture and frequency dependent conductivity as an obstacle to determining electrical percolation thresholds of cementitious nanocomposites made with carbon nanotubes
Authors: Piana Francesco , Liebscher Marco , Köberle Thomas , Mechergui Imen
Published: May 2023

Impedance spectroscopy was applied to Portland cement and its carbon nanotubes (CNT) composites to measure and describe the electrical conductance phenomena and their dependency on the moisture. Two series of composites were prepared, one with multi-walled, and the other with single-walled CNTs. The percolation concentration was reached only with the single-walled CNTs between 0.10 and 0.25 wt%; it was therefore possible to compare a percolative and a non-percolative system. The kinetic of the drying process was measured in the range of 24 h and described by a decay model with a stretched exponential to be correlated with the composite composition. The polarization phenomena occurring in the materials before and after the moisture removal were modelled with logistic sigmoid and explained by the morphology. In particular, the three found sigmoid were correlated to the polarization phenomena occurring at well-defined structural levels of the specimens. Their mathematical definition was shown to be fundamental for a correct interpretation of the Cole-plots of the real conductivity. Such phenomena presented a peak of intensity at a well define frequency but their effects spread across a broad range of Hertz. Moreover, over the AC frequency of 10 Hz, the conductive effect of the moisture overlapped the conductivity increase caused by the percolative network of the CNT. A dry sample is therefore necessary for accurately evaluating the source of the conductivity, a distinction which is crucially important for sensing applications.
An experimental study of the adjacency constraint on the genitive subject in Japanese
Authors: Nambu Satoshi , Nakatani Kentaro
Published: May 2023

We present the results of two acceptability judgment and three self-paced reading experiments exploring the source of degradation effects on the acceptability of genitive subjects caused by having them not adjacent to the verb. From a syntactic perspective, Miyagawa (2011) attributes this adjacency constraint to his assumption that the genitive subject is situated in Spec-vP, lower than adverbials adjoined to vP or higher. This theory thus predicts that adverbials lower than vP can intervene between the genitive subject and the verb without degrading acceptability. To test this issue and examine the time course of the intervention effects, our experiments varied the number and the types of interveners. Whereas the results of our acceptability judgment experiments straightforwardly confirmed the purported intervention effects, the self-paced reading experiments provided results that cannot be explained in structural terms alone. First, the reading times of the verb and/or the head noun were greater when the genitive subject was adjacent to the verb, an effect that has not been reported in the previous literature. Secondly, the summed reading times of the preverbal regions showed opposite patterns: i.e., the reading times were greater when the genitive subject was not adjacent. Finally, regarding the types of interveners, we found that temporal adverbs and locative PPs, but not manner adverbs, were read significantly slower when they followed the genitive subject. We argue that a hybrid account incorporating a syntactic hypothesis with expectation-based incremental processing theories is called for to account for the whole range of data. 
Identifying generalizable knowledge from the distribution of tonotactic accidental gaps in Mandarin
Authors: Jin Shao-Jie , Wang Sheng-Fu , Lu Yu-An
Published: May 2023

This study investigates tonotactic accidental gaps (unattested syllable-tone combinations) in Mandarin Chinese. In a corpus study, we found that, independent of syllable type, T2 (rising) and T3 (falling-rising) gaps were over-represented, whereas T1 (high level) and T4 (falling) gaps were under-represented. We also observed fewer T1 gaps with voiceless onsets and more T2 and T3 gaps with voiceless onsets, a pattern that is consistent with cross-linguistic observations. While these trends were generally reflected in a wordlikeness rating experiment by Mandarin listeners, their judgements of these gaps, similar to those of real words, were also guided by neighborhood density. Furthermore, T2 gaps with real-word T3 counterparts were rated as more wordlike, a result attributed to the T3 sandhi in Mandarin Chinese. Finally, we used harmonic scores generated from the UCLA Phonotactic Learner to explicitly test the role of lexical knowledge and markedness constraints in modeling speakers’ tonotactic knowledge reflected in the wordlikeness ratings. We found that grammars induced from lexical data were the most successful at predicting wordlikeness ratings of gaps and lexical syllables combined. However, when focused on the ratings of tonotactic gaps, grammars with markedness constraints informed by cross-linguistic observations were more successful even without the constraints being weighted on lexical data. The results show how lexical knowledge and universal markedness, which is not entirely learnable from the lexicon, may account for some tonotactic generalizations.
Ficus deltoidea Leaf Alters Oxidative Stress, Protein Homeostasis and Ubiquitin-Proteasome Pathways in Fatty Acid-Induced Cell Line
Authors: Abrahim Noor Nazirahanie , Aminudin Norhaniza , Abdul-Rahman Puteri Shafinaz
Published: May 2023

Research background. Ficus deltoidea (mistletoe fig) is a shrub well known among locals in Malaysia primarily for its treatment of toothaches, colds and wounds. The aim of this study is to determine the potential of leaves, sourced from three different varieties of F. deltoidea, to exhibit antioxidant activity, a reduction of lipid concentration, and protein expression in steatosis-induced liver cell lines.
Experimental approach. The leaves of three F. deltoidea varieties, namely Ficus deltoidea var. angustifolia, Ficus deltoidea var. trengganuensis and Ficus deltoidea var. kunstleri, were subjected to water extraction. The resulting crude extracts were fractionated using water and ethyl acetate. Palmitic acid was used to induce lipid accumulation (steatosis) in human liver (WRL68) cells, before all the samples were tested for their lipid-reducing activity. Several proteomic approaches were incorporated. The changes in protein expression were determined using 2-dimensional gel electrophoresis separation, whereas identification of our protein spots of interest was carried out via matrix-assisted laser desorption/ionization time-of-flight.
Results and conclusions. Ficus deltoidea var. kunstleri alone demonstrated the ability to reduce lipids at the highest tested concentration (200 μg/mL) and was, therefore, used for subsequent experiments. Treatment with Ficus deltoidea var. kunstleri was found to restore redox status by increasing superoxide dismutase and glutathione peroxidase amounts and decreasing malondialdehyde formation. Six proteins were successfully identified; these were heat shock protein beta-1 (HSPB1), proteasome subunit alpha type 1 (PSMA1), glutathione S-transferase omega 1 (GSTO1), peroxiredoxin-1 (PRDX1), histone H2B (HIST1H-2BD) and ubiquitin c-terminal hydrolase L3 (UCHL3). Through bioinformatics analysis, it was found that these proteins were significantly involved in specific pathways such as oxidative stress (PRDX1 and GSTO1), protein homeostasis (HSPB1) and degradation (UCHL3 and PSMA1).
Novelty and scientific contribution. F. deltoidea pretreatment was shown to reduce lipid accumulation, thus improving the redox status and protein homeostasis. This suggests the role of F. deltoidea as a preventive mechanism in non-alcohol fatty liver disease.
Инструменты субординации и качество предоставления публичных благ: кейс-стади Петрозаводска, 2016-2021
Authors: Турченко Михаил
Published: May 2023

Статья построена на кейс-стади Петрозаводска, столицы Республики Карелия, где с 2015 г. отменены прямые выборы главы города. В работе показано, какие инструменты региональная власть использовала для встраивания местного самоуправления, уже лишенного значительной доли автономии, в единую управленческую “вертикаль”. Среди них были как неформальные практики, при которых власти региона “курировали” вопросы местного значения, так и более формализованные рычаги влияния. В числе последних выделены: (1) контроль региона над деятельностью конкурсной комиссии по отбору кандидатур на пост главы города через фигуру ее председателя, (2) восстановление внутри административной структуры местного самоуправления должности, предназначенной для члена команды главы региона, (3) назначение на пост мэра бывшего подчиненного губернатора, (4) формирование городской администрации из чиновников правительства региона. Анализ инструментов субординации, используемых региональной властью в отношении местного самоуправления, вносит вклад в литературу, рассматривающую проникновение авторитарных практик на локальный уровень. В статье также рассмотрена связь между моделью организации местной власти и качеством предоставления публичных благ. Кейс-стади Петрозаводска показывает, что в трех из четырех сфер городского хозяйства, которые должны были иметь высокий приоритет у администрации после отмены прямых выборов мэра и отставки прежнего главы в конце 2015 г. (нехватка муниципального жилья для малоимущих граждан, очередь в детские сады, очистка вод городской ливневой канализации), сохранились проблемы. Таким образом, проведенный анализ не дает достаточных оснований для вывода, что переход от процедуры прямого избрания главы Петрозаводска к его фактическому назначению привел к улучшению качества муниципального управления. Этот вывод согласуется с представленными в научной литературе данными об отсутствии систематической связи между моделью организации местной власти в России и качеством предоставляемых ею публичных благ.
Chinese Customs Regulations on Cross-Border E-Commerce: A Growth Opportunity for Foreign Enterprises and Chinese Commercial Platforms
Authors: Ruiz Miriam
Published: May 2023

The fast improvement of communications since 1980´s has sped up the way of world-wide consumption. The embrace of globalization and all the changes and improvements that come with it, such as new technologies, faster and more accessible routes and ways of transportation, have created a new way to sell and buy goods named electronic commerce or e-commerce.This new way of commerce was officially adopted in May, 1998 in the Declaration on Global Electronic Commerce of the Second Ministerial Conference of the World Trade Organization, which recognizes the growth of this new way of trade and the new opportunities it brings with. Since then, the term of electronic commerce, or e-commerce, is understood as to mean the production, distribution, marketing, sale or delivery of goods and services by electronic means1. Even if today e-commerce is not a new subject, we can say it has become a popular and stable way of consumption, job, and income source, not only for the seller and buyer, but also for all the intermediaries involved in the process. In this article, the characteristics of cross-border e-commerce and its implication on Chinese Customs legislations and commercial platforms will be analyze by noting their main characteristics and the challenges shared for development, as well as the effects they generate among consumers, enterprises and the government.
Caution in usage of clobazam in elderly patients
Authors: Divya KP  , Cherian Ajith , Aswin R M
Published: May 2023

Clobazam, one of the newer benzodiazepines, is now used extensively as first add on therapy in focal epilepsy.

A 67-year-old diabetic and hypertensive gentleman with a history of frontal contusion one year ago, presented with clustering of seizures. He was started on clobazam 20 mg, and levetiracetam 1000 mg/day. Recurrence of seizures prompted a dose escalation of clobazam to 40 mg/day. The patient developed hepatic encephalopathy and his decompensation was probably precipitated by the use of high dose of clobazam. Clobazam was thus gradually tapered off along with hepatic precoma regimen, and other supportive measures leading to an uneventful recovery.

Caution must be taken while administering clobazam to elderly and debilitated patients or those with organic brain syndrome as they are more prone to the central nervous system (CNS) depressant activity of benzodiazepines. Since clobazam requires dealkylation and hydroxylation prior to conjugation, it should be used with caution in patients with hepatic involvement.
Ruptura e enfrentamento: uma leitura de Macário, de Álvares de Azevedo
Authors: Inácio Francilda Araújo
Published: May 2023

Este texto tem por objetivo focalizar o Movimento Romântico, surgido no século XVIII,
como marca do início de um processo histórico de Descontinuidade e questionamento da cultura. O drama Macário, de Álvares de Azevedo, será aqui observado como representante de uma tendência que rompeu com o cânone clássico, imprimindo no âmbito da literatura brasileira um avanço dos padrões estéticos da época.
A família do paciente terminal: um estudo à luz da logoterapia
Authors: Rodrigues Icaro Arcênio de Alencar
Published: May 2023

A terminalidade da vida humana historicamente tem produzido vários sentimentos, principalmente aqueles que uma doença grave pode ocasionar, como o medo da morte e do sofrimento. A vivência de familiares cujo um dos integrantes desta apresenta doença crônico-degenerativa em fase terminal é alterada, afetando a interação entre estes e a equipe hospitalar. Deste modo cabe verificar por meio de revisão bibliográfica quais as dificuldades emocionais que enfrentam este grupo familiar, os benefícios que esta família obtém por meio da aceitação de que um familiar esteja acometido de doença cujo diagnóstico seja terminal, assim como quais as consequências destes fatores sobre a saúde mental da família. Esta pesquisa foi apoiada pelo referencial teórico da logoterapia, corrente da psicologia que apresenta a possibilidade intelectual de encontrar sentido para a vida, inclusive diante do sofrimento inevitável. Verificou-se que os sentimentos de tristeza, angústia, revolta, por exemplo, acometem os familiares na relação com o membro enfermo, além de que a facilitação da comunicação entre estes e o familiar doente, principalmente na forma de ritual de despedida, promove o alivio das culpas e tristezas, e, deste modo, maior saúde mental para ambas as partes.
Contribuições da perspectiva histórico-cultural no processo de ensino e aprendizagem do Desenho Técnico
Authors: Araujo Junior Aarão Pereira de
Published: May 2023

O objetivo deste trabalho é mostrar a importância da perspectiva histórico-cultural proposta por Lev Vygotsky para o processo de ensino e aprendizagem do desenho técnico na prática cotidiana de professores e alunos. Neste trabalho buscaram-se verificar as possibilidades de unir as duas ferramentas tratadas nesta pesquisa: o desenho técnico tradicional, por intermédio de instrumentos ditos tradicionais como compasso, esquadros e régua e o desenho assistido por computador (CAD) bem como da criação de novos ambientes que permitam novas possibilidades de ensino e aprendizagem em que o aluno constrói o seu conhecimento e tem o controle do processo dessa construção.
Avaliação do desenvolvimento de um bosque de sabiá (Mimosa caesalpiniifolia, Benth.) (Fabaceae) no Agreste Paraibano
Authors: Pereira Frederico Campos , Silva José Maricléferson Gomes e , Dantas Aline R. de O. , Lima Anny Kelly Vasconcelos de Oliveira
Published: May 2023

O Sabiá (Mimosa caesalpiniifolia, Benth) é uma leguminosa tropical arbórea de pequeno porte atingindo até sete metros de altura. Largamente utilizada na região Nordeste como forrageira e produtora de mourões, estacas, forquilhas, lenha e carvão, empregada com muito sucesso no reflorestamento de solos tropicais erodidos e degradados. O presente trabalho consiste no acompanhamento de um plantio convencional de cunho orgânico (sem o uso de pesticidas e adubos químicos), visando verificar os índices de sobrevivência das mudas da espécie Mimosa caesalpiniifolia. Estudou-se também o desenvolvimento das mudas plantadas após 2 anos, seus níveis de crescimento como: altura, medições de circunferência a 30 centímetros e a 1,30 metros de altura do solo. Os resultados obtidos com as medições atestam um desenvolvimento satisfatório no que tange a altura das plantas, circunferência aos 0,30 m e a 1,30 m de altura do solo, apesar dos índices menores observados para a parcela da área degradada. Os índices de sobrevivência também foram bastante expressivos, atingindo média acima de 91,5%, o que pode representar uma fonte de renda para a pequena propriedade da zona rural de cidades do Agreste Paraibano.
Educação escolar indígena - território etnoeducacional: relato de experiência
Authors: Gomes Márcia Maria Costa
Published: May 2023

Este artigo é fruto de uma experiência vivida na I Conferência Regional sobre Educação Escolar Indígena, sediada em Caucaia-CE, Brasil no período de 24 a 27 de março de 2009. O objetivo deste relato é fazer uma breve descrição e análise sobre a proposta levantada pelos representantes do Governo Federal sobre a política de regionalização nos territórios indígenas, definida como território etnoeducacional. A metodologia desenvolvida foi a bibliográfica e de alguns depoimentos dos atores sociais que participaram dessa Conferência Regional sobre Educação Escolar Indígena. Constatou-se que a apresentação dos representantes do governo na mesa redonda cujo Eixo Temático I foi “Educação Escolar, Territorializada e Autonomia os Povos Indígenas” não ficou clara e objetiva; o que causou discussões e insatisfações dos agentes sociais envolvidos, ou seja, dos representantes indígenas presentes. Desta forma, evidenciou que não houve compreensão na política de regionalização denominada de Território Etnoeducacional pela ausência de linguagem coloquial informal e acessível para os representantes indígenas presentes.
A eletrização do canudo e uma analogia com o circuito RC
Authors: Rodrigues Eriverton Da Silva , Freire Morgana Lígia De Farias
Published: May 2023

Os trabalhos realizados pela comunidade científica são traduzidos pelas construções de teorias, que geralmente são de difícil assimilação. Talvez, esse fato deva-se a não familiaridade e a linguagem usada, principalmente com relação às teorias da Física. Para os desenvolvimentos teóricos e experimentais do conceito de eletrostática e eletromagnetismo a evolução do ensino-aprendizagem foi de suma importância. No entanto nosso interesse é refletir como isso pode ser revelado através de uma analogia bastante interessante envolvendo o processo de eletrização do canudo e o circuito RC. Dessa maneira, é de suma importância destacar que uma abordagem simples pode permitir uma problematização do conteúdo, fazendo com que tenhamos interação com o experimento e compreensão dos fenômenos físicos envolvidos em eletrostática e eletromagnetismo.
O exercício da subjetividade em confissões de Santo Agostinho
Authors: Silva Maria Célia Ribeiro da
Published: May 2023

A figura afetiva e irreverente de Santo Agostinho é representativa de um homem envolto em dúvidas e especulações relativas a questões do corpo e do espírito, numa busca incessante da descoberta de Deus como fonte de toda a verdade. Esse é o alicerce de uma de suas obras mais conhecidas – “Confissões” (1987) -, um relato autobiográfico em que o autor se expõe ao exercício da subjetividade, do autoconhecimento, ao travar um movimento entre a racionalidade humana e a onipotência divina, momento em que se deixa entrever, talvez, um rasgo de liberdade humana em Agostinho, mas só nesse momento, visto que, ao final das Confissões, essa liberdade é suplantada por um homem já converso, desejoso de louvar e dar glória a Deus. O objetivo deste ensaio é, portanto, refletir como o exercício da subjetividade está esboçado em alguns livros da obra “Confissões”, considerando o conceito de livre-arbítrio, que depois será retomado pelo bispo hiponense em “O livre-arbítrio” (1995), obra em que trata do problema da liberdade humana e da existência do mal, abordando a sua essência e origem.
Suporte ao formalismo para análise de tarefas TAOS através da ferramenta iTAOS – um processo evolutivo
Authors: Medeiros Francisco Petrônio Alencar de , Silva Júnior Nielson José Pontes da , Lula Júnior Bernardo , Oliveira Karolyne Maria Alves de
Published: May 2023

O resultado da análise da tarefa é um documento contendo a descrição detalhada e hierarquizada do trabalho segundo o ponto de vista do usuário e pode ser aplicado para apoiar o projetista em três momentos: especificação das funcionalidades do sistema, projeto da interface com o usuário e elaboração de manuais de treinamento. O surgimento de formalismos, como é o caso do TAOS, foi um passo importante para melhorar a qualidade das descrições das tarefas, principalmente do que diz respeito à colaboração entre profissionais de diferentes áreas que passaram a usar uma linguagem formal comum. Realizar essa análise sem a disponibilidade de uma ferramenta específica implica em diversos problemas, daí a necessidade da automatização desse processo com uma ferramenta (iTAOS). O principal objetivo desse trabalho é apresentar o processo evolutivo pelo qual passou o iTAOS e tornar esse artigo a referência para a terceira release da ferramenta, apresentando suas novas funcionalidades e métodos de desenvolvimento: overview da árvore, desfazer e refazer operações, exportar a árvore e integração com o FastInterface.
The effect of GHRM on the sustainable performance of private companies in Qatar
Authors: Alenzi Mohamad A S , Jaaffar Amar Hisham , Khudari Mohammad
Published: May 2023

This study investigates the impact of green human resource management (GHRM) practices on sustainable performance (SP) in Qatari private companies. A questionnaire survey was conducted among 216 private companies, including top management, human resource managers, quality managers, and employees. Reliability and validity tests were performed on the survey forms, followed by a partial least squares structural equation modelling (PLS-SEM) technique to evaluate the hypothesis. The study found evidence that GHRM practices have a positive impact on SP outcomes in Qatar's private companies. This empirical link between GHRM practices and SP contributes to the literature on GHRM. The results further showed that GHRM practices can lead to green empowerment among employees, thereby improving long-term sustainability. The research demonstrates the importance of GHRM practices for private companies to achieve sustainable development goals. The paper highlights the need to incorporate GHRM practices in the private sector to encourage employees to take an active role in promoting environmental sustainability, leading to long-term business success. The study offers practical implications for private companies in Qatar, suggesting that GHRM practices should be implemented to improve SP.
Combined Treatment of a Patient with High Bile Duct Stricture
Authors: Semenov Dmitriy Yurievich , Morozov Viktor Petrovich , Bogdanov Petr Ivanovich , Did-Zurabova Elena Sergeevna , Rebrov Anton Aleksandrovich , Melnikov Vasiliy Valerievich , Kulikov Dmitriy Viktorovich , Babazada Rza Ilgar ogly
Published: May 2023

Minimally invasive percutaneous techniques, staged as part of the combined treatment of high stricture complications of the biliary tract, demonstrated high efficiency in the short term. On the other hand, the use of self-expanding nitinol stents as a definitive treatment for non-tumor stricture of the biliary tract in long-term life prognosis cannot be recommended as a routine intervention. The use of stents in these cases can only be justified in the absence of alternative treatment options, subject to frequent monitoring of the biliary tract.
High-Dose Brachytherapy in Chemoradiation Schemes of Patients
with Oral Mucosa Cancer
Authors: Moshurov Ivan Petrovich , Korotkikh Natalia Viktorovna , Kamenev Dmitry Yurievich , Tsurikova Anastasia Vladimirovna , Kulikova Irina Nikolaevna
Published: May 2023

The aim of the study was to improve clinical outcomes of oral mucosa cancer in case of surgical treatment failure.Materials and methods. A clinical case of combined radiation treatment of a patient with oral floor mucosa cancer St III T3N1M0 was presented. Pathogistological diagnosis # xxxxxx was: highly differentiated squamous cell carcinoma. A treatment plan was developed. Chemoradiotherapy at the first stage included 3 courses of intra-arterial chemotherapy (Selective (superselective) embolization (chemoembolization) of tumor vessels in the basin of the left and right facial and left lingual arteries, cisplatin 150 mg, combined with a daily infusion of 5-fluorouracil 4000 mg), with an interval 21 day. Chemoradiotherapy at the second stage included volume modulated arc therapy (VMAT) on the area of ​​the primary tumor (oral floor mucosa) and the regional metastasis pathways (total boost dose 60 Gy to the area of ​​regional lymph flow, otal boost dose 50 Gy to the oral cavity). Chemoradiotherapy at stage 3 included interstitial radiation therapy. A single boost dose (SBD) for the primary focus was 3 Gy/per fraction, 2 times a day, with an interval of 6 hours until total boost dose reached 21 Gy, 7 fractions.Results. After treatment, a complete regression of the tumor was noted. No pathological accumulation of radiopharmaceuticals, features of the tumor process was detected on PET/CT 48 months after treatment.Conclusions. Chemoradiotherapy combined with brachytherapy can be considered as an equal alternative to surgical treatment of patients with oral mucosa cancer.
Modern Approaches to the Study of Liver Failure on Biological Models
Authors: Laptiyova Anastasia Yurievna , Glukhov Alexander Anatolievich , Andreev Alexander Alekseevich , Verlyanko Maria Sergeevna , Ostroushko Anton Petrovich
Published: May 2023

Introduction. To date, according to WHO, liver failure (LF) is one of the ten leading causes of death in the elderly in developing countries. In developed countries, LF occurs in 0.03% of the population, but mortality and complication rate remain high. WHO predicts that in the next 10-20 years, mortality from liver diseases will increase by 2 times. In this regard, prevention and treatment of liver failure is of great medical and social significance, remains relevant and requires in-depth study on biological models.The aim of the study was to systematize the data on modern approaches to study liver failure on biological models.Material and methods. The authors reviewed data in PubMed, Cochrane Library, ScienceDirect, eLIBRARY. The search was conducted on the keywords "liver failure", biological model, "liver surgery", "liver failure", "modeling of liver failure", "biological model" and limited to the period 2010-2021. In addition, a manual search of papers in the peer-reviewed journals was carried out. Criteria for exclusion were: description of individual clinical cases, data from books and documents, comparison of clinical outcomes. Out of 109 initially identified sources, 40 sources were included in the final analysis.Results. To date, there are several ways to simulate acute liver failure: surgical, toxic and combined. Chronic liver failure is also simulated diversely: toxically (tetrachloromethane, thioacetamide, dipin, sovtol-1, etc.); surgically (ligation of the bile ducts); dietarily (choline-deficient, etc.); genetically (introduction of exogenous genes into the germ line, combination of hepatotoxins with hepatocarcinogens). As stated, LF simulation has features associated with a high rate of regenerative processes in the liver; the fact allowing it to compensate for damage relatively quickly.Conclusion. There are many techniques to simulate hepatic pathology, differing in damaging factors, the degree of damage and the reversibility of the process, different manifestations of biochemical and morphological changes. When choosing an option to reproduce liver failure, the researcher should take into account the advantages and disadvantages of the model, the conditions for conducting and the expected result of the experiment, and also choose the model that most accurately illustrates the clinical picture of this pathological condition.
Israil Perelman: the shore of his life, or the corners of childhood and adolescent. To the 130th of birthday
Authors: Larichev Andrey Borisovich
Published: May 2023

The fate of Professor Israil Moiseevich Perelman (1892-1954) is inextricably linked with the history of the Minsk Medical University and the Minsk Provincial Hospital, the Borisov Regional Hospital and the surgical service in Gorki, Gomel and Mogilev. He stood at the origins of the formation of medical universities in Vitebsk, Ordzhonikidze, Novosibirsk and Yaroslavl. It all started with the fact that among the many settlers who came to the promised land of White Russia was Moses Perelman. He was the same Jewish poor who were not allowed to cross the limits of the "Pale of Settlement". Without any preferences for choosing a place of permanent residence, Perelman chose the factory outskirts of Minsk Lyakhovka. This place is unattractive, but here, along with many thousands of the same "new settlers", starting from zero, it was possible to make plans for the future and vigorously implement them. An artistic and documentary review of the origins of this settlement, its description of everyday life allows us to imagine the atmosphere of the daily life of those who settled there, took root and gave birth to a new generation. It is this close relationship between the past and the future that makes it possible to understand that in any conditions there is a potential for the formation of good abilities and talents, which, in particular, Israil Perelman possessed. Undoubtedly, the parents were the determining factor in this. They, being guardian angels, provided everything possible and impossible for the upbringing of a purposeful personality in the son, and the difficulties only helped to maintain a sense of gratitude for everything that made the childhood of one of the many boys of the Minsk outskirts carefree - that same factory outback, his small homeland Lyakhovka.
Mikhail Arkadyevich GUBIN - Professor, Honored Maxillofacial Surgeon
(to the 80th of birthday)
Authors: Haciev Genrih Abovich
Published: May 2023

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Prediction of the Complicated Wound Process in Overweight Patients Depending on the Composition of the Intestinal Microbiota
Authors: Suhoparova Elena Petrovna , Zinoviev Evgeny Vladimirovich , Khrustaleva Irina Eduardovna , Kniazeva Ekaterina Sergeevna
Published: May 2023

Introduction. Overweight and imbalance of the intestinal microbiota are risk factors for disruption of reparative processes during the postoperative wound healing. Given the scale of the obesity epidemic in the modern world, the number of overweight patients undergoing surgery for various reasons is also increasing. The potentiation of the risk of a delayed and complicated course of the wound process combined with obesity and violated composition of the intestinal microbiota determines the relevance of this study.The aim of the study was to investigate the composition of the intestinal microbiota in patients with increased body weight, with long-term non-healing and complicated surgical wounds.Methods. The composition of the parietal intestinal microbiota was studied by microbial markers in the blood using gas chromatography in 49 overweight women who underwent planned surgical interventions for aesthetic indications in the period from 2019 to 2020, aimed at correcting body contours. After the operation, women were observed for 6 months, with assessment of the timing of wound healing. We carried out a comparative analysis of the composition of the intestinal microbiota in the different course of the wound process, studied the prognostic significance of individual parameters of the intestinal microbiota in relation to the risk of delayed and complicated wound healing.Results. In the postoperative period, all patients were divided into three groups: group 1 - complicated wound process (n=21), group 2 - delayed wound process 16 (n=16), group 3 - conventional wound process (n=12). Statistically significant differences were found between groups 1 and 2 in terms of "Peptostreptococcus anaerobius (Gr 1) 562.0" (621.76962.03 versus 101.75371.90, respectively, p=0.025) and "Propionibacterium 3.2" (77.57 48.57 vs. 40.44 38.15, respectively, p=0.014). Differences were found between groups 1 and 3 in terms of Endotoxin 0.7 (0.730.58 nmol/ml versus 0.860.48 nmol/ml, respectively, p=0.051). The most risk of the complicated and delayed postoperative wound healing is observed when the values of the parameters were "Propionibacterium 32.0", "Peptostreptococcus anaerobius (Gr 1) 7.0" and "Endotoxin 0.7". Based on the decision tree analysis, 4 risk classes of delayed and complicated course of the wound process were identified. Patients with a combination of Propionibacterium 3.2 and Endotoxin 0.7 had the highest risk.Conclusion. A number of parameters of the intestinal microbiota have a high prognostic value regarding the risk of developing a complicated and delayed course of the wound process in overweight individuals. The data obtained can be used to predict unfavorable healing of surgical wounds. Further research is needed in this area on a larger sample of patients, including males.
Student Transfer Mobility within Indigenous Programs: Pathways of Access or Appropriation?
Authors: Ray Lana , Toombs Elaine , Miron Jeannette
Published: May 2023

Mobility pathways to and from Indigenous programs is one strategy post-secondary education (PSE) institutions employ to support reconciliation, yet data is limited on the status or impact of these pathways. The current study examined program pathways of Indigenous and non-Indigenous learners within Indigenous programming. Fifty-three students were recruited from across PSE institutions in Ontario. Chi squared tests indicated that the majority of students transferring to an Indigenous program were Indigenous, however the study also found that non-Indigenous learners were frequent users of pathways. Results of this study provide cause for consideration about how settler normativity may permeate in pathway development and delivery and recommendations are provided on how PSE can centre Indigenous students in mobility program development.
Māori linked administrative data
Authors: Theodore Reremoana , Boulton Amohia , Sporle Andrew
Published: May 2023

Worldwide, large amounts of administrative data are collected within official statistics systems on Indigenous Peoples. These data are primarily used for government and state policy purposes as opposed to by Indigenous Peoples to support Indigenous agendas (Taylor & Kukutai, 2017). In Aotearoa me Te Waipounamu New Zealand, Māori need high quality data to develop evidence-based policies and programs and to monitor government policies that impact on Māori. In this methodological paper, we describe uses of administrative data for Māori and current barriers to its use. We outline the development of a novel administrative data infrastructure and future longitudinal study. By explicating our Indigenous initiated, designed and controlled data project, we make a methodological contribution to Indigenous Data Sovereignty and Kaupapa Māori (Māori worldview) epidemiology.
Towards "Good" Native Land Governance
Authors: Toh Ming Liang , Tan Liat Choon , Looi Kam Seng , Tan Wee vern , Ujang Muhamad Uznir , Thoo Ai Chin , Azri Nor Suhaibah , Kathitasapathy Shanmugapathy
Published: May 2023

Sarawak is the largest state in Malaysia, where two-thirds of the population are Indigenous. This study aims to evaluate, through the lens of good governance principles, the current practice of the Sarawak State’s formal land governance of lands associated with Native Customary Rights (hereafter known as Native land governance). Being quantitative in nature, this study conceptualises an evaluation framework for good governance principles as applied to Native land governance. Next, this study empirically tests out the framework by adopting a multi-criteria decision-making tool known as The Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). TOPSIS analysis enables the integration of perceptions between State/private groups and Indigenous groups. The output of the TOPSIS analysis is summarised in a strength, weakness, opportunity, and threat (SWOT) format according to the TOPSIS closeness value. Unfortunately, results show that the weaknesses outnumber the strengths in Sarawak’s Native land governance. Among these issues, Indigenous respondents highlight major issues with the Sarawak land registry’s efficiency in delivering outcomes that are equitable for Indigenous land rights. This study ends with recommendations on how the state of Sarawak can move towards compliance with good governance principles in relation to lands associated with Native Customary Rights.
Applying a Critical Policy Lens to Contracting in Indigenous Mental Health: An Ethnographic Study with Urban Indigenous Providers
Authors: Josewski Viviane , Morrow Marina , Smye Victoria , Lavoie Josée , O'Neil John , Mussell William
Published: May 2023

This article reports on the findings of a larger study that explored urban Indigenous providers’ experiences with contracting in mental health and addictions care. The study was undertaken with seven Indigenous and one non-Indigenous non-profit organizations based in diverse large and mid-size cities (off reserve) in British Columbia, Canada. Indigenous and critical theoretical perspectives provided the lens for this ethnographic inquiry. In-depth interviews were the primary data source. Participants’ narratives provide an account of the ideological embeddedness of contracting and how a New Public Management operates to perpetuate colonial power imbalances and structural barriers to culturally safe and equity-oriented care within urban Indigenous communities. Policy and practice implications for government funders are discussed.
Spór o stosunek logiki do matematyki
Authors: Maciaszek Janusz
Published: May 2023

Rozdział drugi poświęciłem omówieniu prób uściślenia podstawowych intuicji wiązanych z logicznością wyrażeń, relacji wynikania i teorii. Były to jednak próby nieudane, gdyż nie usuwały niejasności wiązanych z pojęciami przejrzystości, niezależności tematycznej i uniwersalności. Na tym tle pokazałem spory na temat statusu matematyki, ze szczególnym uwzględnieniem argumentacji zwolenników logicyzmu. [ZE WSTĘPU AUTORA]
Struktura logiczna języka i syntaktyczne kryteria logiczności
Authors: Maciaszek Janusz
Published: May 2023

Przedmiotem trzeciego rozdziału jest język logiki oraz dyskusja nad możliwością formułowania syntaktycznych kryteriów logiczności. Kryterium syntaktyczne może być rozumiane dwojako: 1. czy w języku logiki istnieją "pozycje" lub "miejsca" zarezerwowane dla znaków logicznych?; 2. czy język logiki może być dowolnie bogaty? W rozdziale tym staram się pokazać, że odpowiedź na pierwsze pytanie jest, wbrew pozorom, negatywna. Jednocześnie solidaryzując się z poglądami Quine'a stawiam tezę, że odpowiednie ograniczenie języka może zapewnić logice niezbędną jej uniwersalność. [ZE WSTĘPU AUTORA]
Lokalne i globalne kryteria logiczności
Authors: Maciaszek Janusz
Published: May 2023

Rozdział szósty podsumowuje całą pracę. Staram się w nim sprecyzować znaczenie terminu "kryterium logiczności" i pokazać jaką budowę powinny mieć takie kryteria. Analizując trzy spośród sformułowanych w poprzednich rozdziałach kryteriów logiczności, podejmuję dyskusję na temat zakresu ich stosowania. Na zakończenie szkicuję sposób konstruowania złożonych kryteriów logiczności i pokazuję, że zaproponowane przeze mnie kryterium jest spełnione przez logikę klasyczną i przez intuicjonistyczny rachunek predykatów. [ZE WSTĘPU AUTORA]
Proklos jako komentator Platona
Authors: Komorowski Marcin
Published: May 2023

Not only in Polish philosophical literature non-Christian Neoplatonism of Late Antiquity still lie in the unexplored gap between two domain of the history of philosophy, that of ancient one and that of medieval. The paper has had two aims: to briefly present Proclus' activity at Athens as a commentator on Plato, especially as a commentator on the "Timaeus" and on the "Parmenides", and to set forth the statement, which is hoped that it has been sufficiently proved through philological and philosophical analyses of selected quotation from Proclus, Marinus and Plotinus, that for Proclus, such as for the rest of Neoplatonists of that period, above mentioned activity (i.e. explaining Plato by writing huge commentaries) was essentially a way of expressing new ideas and their own original thought. The author suggest that some of the Proclus' commentaries on Plato might have simply into being as a kind of notes or records of the meetings at the 'Academy', where Proclus with his students was reading and explicating some dialogues selected out of all the Platonic writing. The obvious evidence of that is the structure of Proclean commentaries and especially such a fact that he is quoting and analyzing Platonic texts line by line. The paper also contains the Polish translation of the part of the book III of Proclus' "Commentary on Plato's Parmenides" as a kind of textual illustration of its theses.
Podstawy fizyki Kartezjusza
Authors: Śliwiński Tomasz
Published: May 2023

Le texte ci-dessus traite d'une question-clé pour le jeune philosophe Descartes. Cette dissertation aborde la problématique des fondements du savoir que le philosophe posait pour la première fois dans son traité «Le Monde» (1629-1632). C'est avec ce traite que naît, dans le système de Descartes, le besoin d'établir les bases métaphysiques des nouvelles sciences naturelles et de toute la nouvelle philosophie. En 1630, Descartez n'avait pas encore suffisamment façonné la question de dieu et de sa relation envers le monde, question qui existait tout de même dans son esprit et était novatrice par rapport à ce que l'on ensejgnait à ce sujet au point de susciter la controverse voire méme la réprobation. Cette problématique touchait aux questions physicues au sens large dans le projet de travail du philosophe et établissait la possibilité d'un fonde'ent métaphysique du discours sur l'existence. Cette question, Descartes l'a résolue en embrassant la notion de vérités universalles qu'il a subordonnées au concept du dieu-créateur de l'ordre rationnel du monde. Ces vérités universalles en tant que vérités mathématiques, sont, pour le philosophe non seulement la substance (l'essence) mathétique de l'objet de la connaissance, mais aussi la condition indispensable à la connaissance. Ceci lui a permis une concordance absolue de l'ordre du savoir avec l'ordre réel, que ce savoir décrivait. Ce travail est une reconstruction basée sur la correspondance du philosophe et n'existait pas, à l'époque, comme idée indépendante dans la philosophie de Descartes.
Kilka uwag o pomysłowości ("wit") u Locke'a
Authors: Załuski Tomasz
Published: May 2023

The subject matter of the paper is an analysis of the role of 'wit' in J. Locke's "An Essay Concerning Human Understanding". The analysis shows that this apparently marginal issue plays in Locke's text ambivalent role. Interpreted by Locke as assemblage of ideas on the basis of their similarity, wit is, on the one hand, explicitly excluded from the domain of philosophy and situated within the sphere of aesthetic pleasure. On the other hand wit is an implicit constitutive element of a number of "Essay's" important philosophical issues, especially those of mind and of ideas formation. The analysis of wit may also be regarded as a contribution to the history of the philosophical treatment of wit and some related problems, such as inventiveness.