bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 - 19 from Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers
Authors: Hata Aaron N. , Yeo Alan , Faber Anthony C. , Lifshits Eugene , Chen Zhao , Cheng Katherine A. , Walton Zandra , Sarosiek Kristopher A. , Letai Anthony , Heist Rebecca S. , Mino-Kenudson Mari , Wong Kwok-Kin , Engelman Jeffrey A.
Published: March 2023

PDF file - 11671KB, Supplemental Figure 1. Response of Kras mouse models to MEKi/PI3Ki. Supplemental Figure 2. MEKi/PI3Ki induces G1 arrest and inhibits proliferation of KRAS mutant NSCLC cell lines. Supplemental Figure 3. Combined MEK and PI3K inhibition is necessary for maximal reduction in cell proliferation. Supplemental Figure 4. Apoptotic response of KRAS mutant NSCLC cell lines in response to MEKi/PI3Ki. Supplemental Figure 5. Mutational status of TP53 or STK11/LKB1 does not correlate with apoptotic response to MEKi/PI3Ki. Supplemental Figure 6. Secreted Gaussia luciferase allows for precise quantitation of tumor growth and treatment response. Supplemental Figure 7. Tumor response of KRAS NSCLC xenografts to MEKi/PI3Ki. Supplemental Figure 8. Apoptosis induced by MEKi/PI3Ki is BAX and caspase-3 dependent. Supplemental Figure 9. Modulation of MEK/ERK and PI3Ki/AKT transcriptional output does not correlate with apoptotic sensitivity of KRAS mutant NSCLC cancer cells. Supplemental Figure 10. Modulation of RalGDS signaling does not correlate with apoptotic sensitivity of KRAS mutant NSCLC cell lines. Supplemental Figure 11. Sensitivity to MEKi/PI3Ki does not correlate with BH3 priming. Supplemental Figure 12. siRNA mediated knockdown of PUMA and BIM protects from apoptosis induced by MEKi/PI3Ki. Supplemental Figure 13. Inhibition of BCL-2 alone does not restore apoptotic response in insensitive KRAS mutant NSCLC cell lines. Supplemental Figure 14. Individual protein expression levels of BCL-2 family members do not correlate with sensitivity to MEKi/PI3Ki. Supplemental Figure 15. Inducible ectopic expression of BIM. Supplemental Figure 16. Restoration of apoptosis by ABT-263 leads to MEKi/PI3Ki-induced regression in vivo. Supplemental Figure 17. In vitro derived MEKi/PI3Ki resistant cells. Supplemental Figure 18. Cell lines derived from resistant Kras p53L/L tumors. Supplemental Figure 19. PUMA and BIM mRNA levels do not differ between cell lines derived from treatment naive and resistant Kras p53L/L tumors. Supplemental Table 1. Mutational status of KRAS mutant NSCLC cell lines. Supplemental Table 2. Knockdown efficiency of pLKO shRNA hairpins used in lentiviral screen.
Supplementary Figure 3 from Function-Blocking ERBB3 Antibody Inhibits the Adaptive Response to RAF Inhibitor
Authors: Kugel Curtis H. , Hartsough Edward J. , Davies Michael A. , Setiady Yulius Y. , Aplin Andrew E.
Published: March 2023

PDF file - 124K, PTEN status.
Supplemental Figure Legend from Aurora-A Inhibition Offers a Novel Therapy Effective against Intracranial Glioblastoma
Authors: Van Brocklyn James R. , Wojton Jeffrey , Meisen Walter H. , Kellough David A. , Ecsedy Jeffery A. , Kaur Balveen , Lehman Norman L.
Published: March 2023

Legend for Supplemental Figures S1-S3.
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S1. Proteasome activity is involved in spindle pole localization of MYCN in human neuroblastoma cells. A, Representative images of MYCN localization to spindle poles during mitosis in SK-N-BE and CHP-212 cells with or without exposure of 10μM MG132 for 5h. 0.1% DMSO treated cells served as a control. NuMA is green, MYCN is red, and DAPI (DNA) is blue. Arrows show spindle poles. Scale bars indicate 10 μm. B, Proteasome activity in human neuroblastoma and control (Jurkat) cells.
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S5. Fbxw7 and Huwe1 do not localize to spindle poles during mitosis. A, Representative images of Fbxw7-stained SH-SY5Y, TGW and SK-N-DZ cells in mitosis. A centrosome marker, γ-tubulin is red, Fbxw7 is green, and DAPI (DNA) is blue. Arrows show spindle poles. B, Representative images of Huwe1-stained SH-SY5Y, TGW and SK-N-DZ cells in mitosis. γ-tubulin is red, Huwe1 is green, and DAPI (DNA) is blue. Arrows show spindle poles. Scale bars indicate 10 μm.
Supplementary Table 5 from Inhibiting Tankyrases Sensitizes KRAS-Mutant Cancer Cells to MEK Inhibitors via FGFR2 Feedback Signaling
Authors: Schoumacher Marie , Hurov Kristen E. , Lehár Joseph , Yan-Neale Yan , Mishina Yuji , Sonkin Dmitriy , Korn Joshua M. , Flemming Daisy , Jones Michael D. , Antonakos Brandon , Cooke Vesselina G. , Steiger Janine , Ledell Jebediah , Stump Mark D. , Sellers William R. , Danial Nika N. , Shao Wenlin
Published: March 2023

PDF file - 68KB, Sensitivity of KRAS mutant cancer cells to TNKSi/MEKi combination. Synergistic cell lines are in red (cut-off of synergy score of 2).
Supplementary Methods from The Notch Pathway Inhibits TGFβ Signaling in Breast Cancer through HEYL-Mediated Crosstalk
Authors: Han Liangfeng , Diehl Adam , Nguyen Nguyen K. , Korangath Preethi , Teo Weiwen , Cho Soonweng , Kominsky Scott , Huso David L. , Feigenbaum Lionel , Rein Alan , Argani Pedram , Landberg Goran , Gessler Manfred , Sukumar Saraswati
Published: March 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplementary Table S1 from Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis
Authors: Menard Julien A. , Christianson Helena C. , Kucharzewska Paulina , Bourseau-Guilmain Erika , Svensson Katrin J. , Lindqvist Eva , Chandran Vineesh Indira , Kjellén Lena , Welinder Charlotte , Bengzon Johan , Johansson Maria C. , Belting Mattias
Published: March 2023

Table S1. Label free LC-MS/MS quantification of LRP1 shows no induction by hypoxia.
Supplementary Methods and Figure Legends from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Authors: Faria Claudia C. , Golbourn Brian J. , Dubuc Adrian M. , Remke Marc , Diaz Roberto J. , Agnihotri Sameer , Luck Amanda , Sabha Nesrin , Olsen Samantha , Wu Xiaochong , Garzia Livia , Ramaswamy Vijay , Mack Stephen C. , Wang Xin , Leadley Michael , Reynaud Denis , Ermini Leonardo , Post Martin , Northcott Paul A. , Pfister Stefan M. , Croul Sidney E. , Kool Marcel , Korshunov Andrey , Smith Christian A. , Taylor Michael D. , Rutka James T.
Published: March 2023

Supplementary Methods and Figure Legends
Supplementary data legends from LesionTracker: Extensible Open-Source Zero-Footprint Web Viewer for Cancer Imaging Research and Clinical Trials
Authors: Urban Trinity , Ziegler Erik , Lewis Rob , Hafey Chris , Sadow Cheryl , Van den Abbeele Annick D. , Harris Gordon J.
Published: March 2023

File with legends for supplementary figures and video
Figure S2 from LesionTracker: Extensible Open-Source Zero-Footprint Web Viewer for Cancer Imaging Research and Clinical Trials
Authors: Urban Trinity , Ziegler Erik , Lewis Rob , Hafey Chris , Sadow Cheryl , Van den Abbeele Annick D. , Harris Gordon J.
Published: March 2023

Supplementary Figure 2 presents example of lesion measurement report in LesionTracker
Supplementary Table S1 from Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer
Authors: Acharya Sunil , Yao Jun , Li Ping , Zhang Chenyu , Lowery Frank J. , Zhang Qingling , Guo Hua , Qu Jingkun , Yang Fei , Wistuba Ignacio I. , Piwnica-Worms Helen , Sahin Aysegul A. , Yu Dihua
Published: March 2023

Clinical and pathological features of triple negative patient cohort used for TMA.
Supplementary Methods Table from Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress
Authors: Young Lucy A. , O'Connor Lenka Oplustil , de Renty Christelle , Veldman-Jones Margaret H. , Dorval Thierry , Wilson Zena , Jones David R. , Lawson Deborah , Odedra Rajesh , Maya-Mendoza Apolinar , Reimer Corinne , Bartek Jiri , Lau Alan , O'Connor Mark J.
Published: March 2023

Methods Table: Antibodies
Supplementary Data File from Autofluorescence Imaging of 3D Tumor–Macrophage Microscale Cultures Resolves Spatial and Temporal Dynamics of Macrophage Metabolism
Authors: Heaster Tiffany M. , Humayun Mouhita , Yu Jiaquan , Beebe David J. , Skala Melissa C.
Published: March 2023

Supplementary figures 1-5 and supplementary tables 1-3. Supplementary Figure 1: Fluorescence lifetimes of NAD(P)H and FAD exhibit differences between macrophage polarization states. Supplementary Figure 2: Validation of two-photon wavelength mixing for evaluating autofluorescence and migration effects in 2D cultures and the 3D Stacks microfluidic platform. Supplementary Figure 3: Prolonged co-culture of mouse breast cancer and macrophages yields heterogeneous NAD(P)H and FAD fluorescence lifetime and migration compared to monoculture. Supplementary Figure 4: Primary human tumor cells stimulate changes in NAD(P)H and FAD fluorescence lifetime and cell migration in co-cultured human monocyte-derived macrophages. Supplementary Figure 5: Metabolic changes in human THP-1s following co-culture with MDA-MB-231 human breast carcinoma. Supplementary Table 1: Mouse and Human Macrophage Polarization Gene Panels. Supplementary Table 2: Significance of redox ratio fold change in inhibitor-treated 2D cytokine-stimulated mouse macrophages. Supplementary Table 3: Coefficients of variation (CV) and significance of CV equality for optical redox ratio in 2D cytokine-stimulated mouse macrophages and 3D mouse monocultures and co-cultures.
Table S1 from The Pathognomonic FOXL2 C134W Mutation Alters DNA-Binding Specificity
Authors: Carles Annaïck , Trigo-Gonzalez Genny , Cao Qi , Cheng S.-W. Grace , Moksa Michelle , Bilenky Misha , Huntsman David G. , Morin Gregg B. , Hirst Martin
Published: March 2023

RNA-seq (polyA and ribodepleted) RPKM matrix for protein coding genes from primary AGCT and SVOG3e derived isogenic cell lines.
Figure S4 from Ablation of the Brca1–Palb2 Interaction Phenocopies Fanconi Anemia in Mice
Authors: Park Dongju , Bergin Stephen M. , Jones Dan , Ru Peng , Koivisto Christopher S. , Jeon Young-Jun , Sizemore Gina M. , Kladney Raleigh D. , Hadjis Ashley , Shakya Reena , Ludwig Thomas
Published: March 2023

Brca1L1363P mutation induces premature senescent phenotype in pMEFs
Supplementary Table from Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression
Authors: Midorikawa Yutaka , Yamamoto Shogo , Tatsuno Kenji , Renard-Guillet Claire , Tsuji Shingo , Hayashi Akimasa , Ueda Hiroki , Fukuda Shiro , Fujita Takanori , Katoh Hiroto , Ishikawa Shumpei , Covington Kyle R. , Creighton Chad J. , Sugitani Masahiko , Wheeler David A. , Shibata Tatsuhiro , Nagae Genta , Takayama Tadatoshi , Aburatani Hiroyuki
Published: March 2023

Table S1 shows Clinical features. Table S2 shows Patient/sample information and NGS statistics. Table S3 shows Methylation status of CpG sites of WNT targets with CTNNB1 mutation. Table S4 shows Chromosomal aberrations.
Table S6 from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Differentially expressed genes between cases with and without chromothripsis
Table S5 from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Recurrent fusion genes and parameters of the regression analysis
Table S4 from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Chromosome regions with significant differences in copy-number gains and losses between cases with and without chromothripsis
Table S3 from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Chromosome regions significantly enriched for chromothriptic events and breast cancer drivers statistically overrepresented in such regions
Figure S1, Figure S2 from Upregulation of E3 Ubiquitin Ligase CBLC Enhances EGFR Dysregulation and Signaling in Lung Adenocarcinoma
Authors: Hong Shiao-Ya , Kao Yu-Rung , Lee Te-Chang , Wu Cheng-Wen
Published: March 2023

Figure S1- CBLC expression is upregulated in NSCLC cell lines and clinical patients. Figure S2- Negative correlation between CBLC promoter methylation and mRNA expression in TCGA LUAD and LUSC studies.
Supplementary Files Legends from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Legends of Supplementary Figures and Tables
Supplementary Figure 4 from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Unsupervised clustering analyses of RNAseq data for ER+, HER- liver metastases of the CATCH cohort (a) and luminal tumors from the DKFZ-HIPO17 cohort (b)
Supplementary Methods from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer
Authors: Kim Kee-Beom , Kim Youngchul , Rivard Christopher J. , Kim Dong-Wook , Park Kwon-Sik
Published: March 2023

Sequences of guid RNAs, shRNAs, oligo nucleotides for cloning, List of antibodies, Methods of immunohistochemistry for RBL2, FGFR1, and PLCG1 on tumor microarrays
Supplementary Fig 2 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer
Authors: Kim Kee-Beom , Kim Youngchul , Rivard Christopher J. , Kim Dong-Wook , Park Kwon-Sik
Published: March 2023

Immunoblot for FGFR1 in primary cells derived from lung tumors. FGFR1 expression in primary cells from a tumor developed in Fgfr1lox/lox Rb1/Trp53/Rbl2 mouse (cohort #1) is reduced but readily detected, suggesting incomplete recombination of Fgfr1 lox alleles. GAPDH verifies equal loading of total proteins.
Supplementary Data Tables S1-S15 from State-Transition Analysis of Time-Sequential Gene Expression Identifies Critical Points That Predict Development of Acute Myeloid Leukemia
Authors: Rockne Russell C. , Branciamore Sergio , Qi Jing , Frankhouser David E. , O'Meally Denis , Hua Wei-Kai , Cook Guerry , Carnahan Emily , Zhang Lianjun , Marom Ayelet , Wu Herman , Maestrini Davide , Wu Xiwei , Yuan Yate-Ching , Liu Zheng , Wang Leo D. , Forman Stephen , Carlesso Nadia , Kuo Ya-Huei , Marcucci Guido
Published: March 2023

Table S1. Differentially expressed genes for c_1 vs c_1^* Table S2. Differentially expressed genes for c_2 vs c_1^* Table S3. Differentially expressed genes for c_3 vs c_1^* Table S4. Differentially expressed genes for c_2 vs c_1 Table S5. Differentially expressed genes for c_3 vs c_1 Table S6. Differentially expressed genes for c_3 vs c_2 Tables S7-S10. Differentially expressed genes for early, transition, persistent, and leukemia events. Tables S11-S14. GO terms enriched for early, transition, persistent, and leukemia events. Table S15. Top 1% of eigengenes.
Supplementary Data 2 from FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer
Authors: Kim Kee-Beom , Kim Youngchul , Rivard Christopher J. , Kim Dong-Wook , Park Kwon-Sik
Published: March 2023

Result of GO-term analysis for differentially expressed genes between control and FGFR1-expressing preSC
Supplementary Data and Tables from Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential
Authors: Beri Pranjali , Popravko Anna , Yeoman Benjamin , Kumar Aditya , Chen Kevin , Hodzic Enio , Chiang Alyssa , Banisadr Afsheen , Placone Jesse K. , Carter Hannah , Fraley Stephanie I. , Katira Parag , Engler Adam J.
Published: March 2023

Complete Supplemental Figures 1-8 and Supplemental Tables 1-2 are embedded in this file. Each item contains its respective legend.
Supplementary Figure S1 from Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells
Authors: Carruthers Ross D. , Ahmed Shafiq U. , Ramachandran Shaliny , Strathdee Karen , Kurian Kathreena M. , Hedley Ann , Gomez-Roman Natividad , Kalna Gabriela , Neilson Mathew , Gilmour Lesley , Stevenson Katrina H. , Hammond Ester M. , Chalmers Anthony J.
Published: March 2023

Supplementary figure S1 displays examples of flow cytometry gating for FACS sorted cell populations, abrogation of Chk1 phosphorylation by VE-821 in GSC and patterns of γ-H2AX staining produced by replication stress.
Supplementary Figures from Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2
Authors: Mao Ninghui , Gao Dong , Hu Wenhuo , Gadal Sunyana , Hieronymus Haley , Wang Shangqian , Lee Young Sun , Sullivan Patrick , Zhang Zeda , Choi Danielle , Rosen Neal , Sawyers Charles L. , Gopalan Anuradha , Chen Yu , Carver Brett S.
Published: March 2023

The supplementary figures provide additional data demonstrating that ERG represses RTK-PI3K signaling through direct transcriptional repression of IRS2 across multiple model systems. Additional data is provided showing the biologic role of ERG and PI3K signaling in promoting cell proliferation and migration.
Supplementary Data from ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway
Authors: Fang Zihui , Wang Yue , Wang Zehua , Xu Meishu , Ren Songrong , Yang Da , Hong Mei , Xie Wen
Published: March 2023

Supplemental Methods
Supplementary Tables from Comprehensive Analysis of Radiomic Datasets by RadAR
Authors: Benelli Matteo , Barucci Andrea , Zoppetti Nicola , Calusi Silvia , Redapi Laura , Della Gala Giuseppe , Piffer Stefano , Bernardi Luca , Fusi Franco , Pallotta Stefania
Published: March 2023

Supplementary Tables 1-2. STable 1: Table of the results of differential radiomic analysis between dead and alive patients from the Lung1 dataset (Aerts et al., 2014). STable 2: Table of the results of differential radiomic analysis across different disease stages for patients from the Lung1 dataset (Aerts et al., 2014).
Supplementary Data from Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance
Authors: Irurzun-Arana Itziar , McDonald Thomas O. , Trocóniz Iñaki F. , Michor Franziska
Published: March 2023

Supplemental data for the main manuscript. Contains equation description of the main features of the framework, description of the pharmacokinetic models and parameter estimates used for the simulations of the treatment effects, additional model fitting results and synergy/antagornism assesments, analysis of different dosing schedules and four different demos of the R package.
Supplementary Table S2 from Genetic Variants Implicate Dual Oxidase-2 in Familial and Sporadic Nonmedullary Thyroid Cancer
Authors: Bann Darrin V. , Jin Qunyan , Sheldon Kathryn E. , Houser Kenneth R. , Nguyen Lan , Warrick Joshua I. , Baker Maria J. , Broach James R. , Gerhard Glenn S. , Goldenberg David
Published: March 2023

Supplemental Table 2. Hereditary cancer syndromes associated with increased non-medullary thyroid cancer risk
Figure S4 from Microenvironmental Cues Determine Tumor Cell Susceptibility to Neutrophil Cytotoxicity
Authors: Gershkovitz Maya , Fainsod-Levi Tanya , Khawaled Saleh , Shaul Merav E. , Sionov Ronit V. , Cohen-Daniel Leonor , Aqeilan Rami I. , Shaul Yoav D. , Fridlender Zvi G. , Granot Zvi
Published: March 2023

Supplemental Figure S4. EMT increases TRPM2 expression and renders cells susceptible to neutrophil cytotoxicity. A. Representative images showing control and Snail overexpressing 4T1 cells. B. Snail expression in control and Snail overexpressing 4T1 cells. C. qPCR analysis of TRPM2, Vimentin (Vim.) and E-Cadherin (E-Cad.) expression in control and Snail overexpressing 4T1 cells. D. Extent of neutrophil cytotoxicity in co-culture with 4T1 control cells (Cont.) or 4T1 cells induced to undergo EMT by Snail overexpression (Snail). E. Representative images showing HMLE cells before (HMLE) and after prolonged treatment with 10 ng/ml TGFÎ² to induce EMT. F. qPCR analysis of TRPM2, Vimentin (Vim.) and E-Cadherin (E-Cad.) in control and TGFÎ²â^'treated HMLE cells. G. Extent of neutrophil cytotoxicity in co-culture with control (Cont.) or TGFÎ²-pretreated HMLE cells that have undergone EMT. H. Representative images showing control and Twist overexpressing HMLE cells. I. Twist expression in control and Twist overexpressing HMLE cells. J. qPCR analysis of TRPM2, Vimentin (Vim.) and E-Cadherin (E-Cad.) expression in control and Twist overexpressing HMLE cells. K. Extent of neutrophil cytotoxicity in co-culture with HMLE control cells (Cont.) or HMLE cells induced to undergo EMT by Twist overexpression (Twist). *p<0.05, **p<0.01.
Figure S1 from Microenvironmental Cues Determine Tumor Cell Susceptibility to Neutrophil Cytotoxicity
Authors: Gershkovitz Maya , Fainsod-Levi Tanya , Khawaled Saleh , Shaul Merav E. , Sionov Ronit V. , Cohen-Daniel Leonor , Aqeilan Rami I. , Shaul Yoav D. , Fridlender Zvi G. , Granot Zvi
Published: March 2023

Supplemental Figure S1. Neutrophils in the premetastatic lung outnumber and interact with disseminated tumor cells. Ly6G immunohistochemistry of metastases-laden lungs from 28 day 4T1 tumor-bearing mouse. Insets are high power magnification.
Video S7 from ΔNp63-Regulated Epithelial-to-Mesenchymal Transition State Heterogeneity Confers a Leader–Follower Relationship That Drives Collective Invasion
Authors: Westcott Jill M. , Camacho Sharon , Nasir Apsra , Huysman Molly E. , Rahhal Raneen , Dang Tuyen T. , Riegel Anna T. , Brekken Rolf A. , Pearson Gray W.
Published: March 2023

Live imaging of explants containing MCFDCISO cells (H2B:mCherry, red, nuclei) with or without 578T cells (H2B:GFP, green, nuclei) showing cell motility.
Supplementary Tables S1-S2 from MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer
Authors: Hillestad Tiril , Hompland Tord , Fjeldbo Christina S. , Skingen Vilde E. , Salberg Unn Beate , Aarnes Eva-Katrine , Nilsen Anja , Lund Kjersti V. , Evensen Tina S. , Kristensen Gunnar B. , Stokke Trond , Lyng Heidi
Published: March 2023

Characteristics of the cervical cancer patient cohort (S1). Hallmarks associated with MRI-based hypoxia levels in cervical cancer (S2)
Video S1 from ΔNp63-Regulated Epithelial-to-Mesenchymal Transition State Heterogeneity Confers a Leader–Follower Relationship That Drives Collective Invasion
Authors: Westcott Jill M. , Camacho Sharon , Nasir Apsra , Huysman Molly E. , Rahhal Raneen , Dang Tuyen T. , Riegel Anna T. , Brekken Rolf A. , Pearson Gray W.
Published: March 2023

Live imaging of clustered spheroids containing SUM159T-dox:Î"Np63 cells {plus minus} doxycycline (H2B:GFP, green, nuclei) showing cell motility.
Supplemental Table ST3 from Linking Transcriptomic and Imaging Data Defines Features of a Favorable Tumor Immune Microenvironment and Identifies a Combination Biomarker for Primary Melanoma
Authors: Gartrell-Corrado Robyn D. , Chen Andrew X. , Rizk Emanuelle M. , Marks Douglas K. , Bogardus Margaret H. , Hart Thomas D. , Silverman Andrew M. , Bayan Claire-Audrey Y. , Finkel Grace G. , Barker Luke W. , Komatsubara Kimberly M. , Carvajal Richard D. , Horst Basil A. , Chang Rui , Monod Anthea , Rabadan Raul , Saenger Yvonne M.
Published: March 2023

Patient characteristics of the DSP cohort.
Supplemental Table ST2 from Linking Transcriptomic and Imaging Data Defines Features of a Favorable Tumor Immune Microenvironment and Identifies a Combination Biomarker for Primary Melanoma
Authors: Gartrell-Corrado Robyn D. , Chen Andrew X. , Rizk Emanuelle M. , Marks Douglas K. , Bogardus Margaret H. , Hart Thomas D. , Silverman Andrew M. , Bayan Claire-Audrey Y. , Finkel Grace G. , Barker Luke W. , Komatsubara Kimberly M. , Carvajal Richard D. , Horst Basil A. , Chang Rui , Monod Anthea , Rabadan Raul , Saenger Yvonne M.
Published: March 2023

Patient characteristics of the metastatic melanoma cohort.
Supplementary Figure S1 from Blocking Angiopoietin-2 Promotes Vascular Damage and Growth Inhibition in Mouse Tumors Treated with Small Doses of Radiation
Authors: Kallio Pauliina , Jokinen Elina , Högström Jenny , Das Suvendu , Heino Sarika , Lähde Marianne , Brodkin Jefim , Korhonen Emilia A. , Alitalo Kari
Published: March 2023

Supplementary Figure S1
Master Regulator Analysis from Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Authors: Voli Florida , Valli Emanuele , Lerra Luigi , Kimpton Kathleen , Saletta Federica , Giorgi Federico M. , Mercatelli Daniele , Rouaen Jourdin R.C. , Shen Sylvie , Murray Jayne E. , Ahmed-Cox Aria , Cirillo Giuseppe , Mayoh Chelsea , Beavis Paul A. , Haber Michelle , Trapani Joseph A. , Kavallaris Maria , Vittorio Orazio
Published: March 2023

Methods for Master Regulator Analysis
Figure S7 from Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Authors: Voli Florida , Valli Emanuele , Lerra Luigi , Kimpton Kathleen , Saletta Federica , Giorgi Federico M. , Mercatelli Daniele , Rouaen Jourdin R.C. , Shen Sylvie , Murray Jayne E. , Ahmed-Cox Aria , Cirillo Giuseppe , Mayoh Chelsea , Beavis Paul A. , Haber Michelle , Trapani Joseph A. , Kavallaris Maria , Vittorio Orazio
Published: March 2023

TEPA did not affect tumor growth in an immunocompromised neuroblastoma xenograft model
Figure S3 from Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Authors: Voli Florida , Valli Emanuele , Lerra Luigi , Kimpton Kathleen , Saletta Federica , Giorgi Federico M. , Mercatelli Daniele , Rouaen Jourdin R.C. , Shen Sylvie , Murray Jayne E. , Ahmed-Cox Aria , Cirillo Giuseppe , Mayoh Chelsea , Beavis Paul A. , Haber Michelle , Trapani Joseph A. , Kavallaris Maria , Vittorio Orazio
Published: March 2023

Effect of copper levels on EGFR phosphorylation and PD-L1 protein stability
Supplementary Material from CRISPR/Cas9-Mediated Point Mutation in Nkx3.1 Prolongs Protein Half-Life and Reverses Effects Nkx3.1 Allelic Loss
Authors: Bowen Cai , Shibata Maho , Zhang Hailan , Bergren Sarah K. , Shen Michael M. , Gelmann Edward P.
Published: March 2023

Supplementary Tables 1-4: Table 1. Primers for PCR amplification for CRISPR/Cas9 mouse models. Table 2. ssODN oligos. Table 3. Primers for genotyping of mouse mutation. Table 4. Antibodies used for immunofluorescence staining. Supplemental Figures 1-8: Supplementary Figure 1 A. Amino acid sequences of human (top) and murine (bottom) NKX3.1 showing consensus (central) sequence and location of serine 185 and 186 indicated by the box in the figure. B. Effect of S186A mutation on half-life of murine Nkx3.1. Supplementary Figure 2 A. Schematic of targeted sites for mutation at locus. Supplementary Fig 3 A. H&E staining of dorsolateral prostatic lobes at different time points. Results similar to those seen with anterior prostates are shown in the figure. Supplementary Fig 4 A. Immunohistochemistry for cytokeratins 5 and 8 in 2-month old anterior prostate lobes. The arrow in the section from Nkx3.1 show an area of early hyperplasia. The arrows in the section from Nkx3.1 show areas of epithelial detachment. Supplementary Figure 5 Nkx3.1 expression. Supplementary Fig 6 Cell proliferation. Supplementary Figure 7 TUNEL staining was done on paraffin sections from dorsolateral prostate lobes of Nkx3.1 , Nkx3.1 , and Nkx3.1 mice at 2, 6, and 10 months of age. Supplementary Figure 8 A. Cleaved caspase 3 staining was done on paraffin sections from both anterior and dorsolateral prostate lobes of Nkx3.1 , Nkx3.1 , and Nkx3.1 mice at 2, 6, and 10 months of age.
legends from Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors
Authors: Lopez Sambrooks Cecilia , Baro Marta , Quijano Amanda , Narayan Azeet , Cui Wei , Greninger Patricia , Egan Regina , Patel Abhijit , Benes Cyril H. , Saltzman W. Mark , Contessa Joseph N.
Published: March 2023

Legends for supplementary figures 1 and 2
Table. S3 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma
Authors: Matsumori Tomoaki , Kodama Yuzo , Takai Atsushi , Shiokawa Masahiro , Nishikawa Yoshihiro , Matsumoto Tomonori , Takeda Haruhiko , Marui Saiko , Okada Hirokazu , Hirano Tomonori , Kuwada Takeshi , Sogabe Yuko , Kakiuchi Nobuyuki , Tomono Teruko , Mima Atsushi , Morita Toshihiro , Ueda Tatsuki , Tsuda Motoyuki , Yamauchi Yuki , Kuriyama Katsutoshi , Sakuma Yojiro , Ota Yuji , Maruno Takahisa , Uza Norimitsu , Marusawa Hiroyuki , Kageyama Ryoichiro , Chiba Tsutomu , Seno Hiroshi
Published: March 2023

Leading edge genes in gene set enrichment analysys using HALLMARK gene set of KRAS_SIGNALING_UP.
Supplementary Figure 1 from Cellular and Genetic Determinants of the Sensitivity of Cancer to α-Particle Irradiation
Authors: Yard Brian D. , Gopal Priyanka , Bannik Kristina , Siemeister Gerhard , Hagemann Urs B. , Abazeed Mohamed E.
Published: March 2023

High-throughput profiling of cellular survival after gamma irradiation.
Fig. S6 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma
Authors: Matsumori Tomoaki , Kodama Yuzo , Takai Atsushi , Shiokawa Masahiro , Nishikawa Yoshihiro , Matsumoto Tomonori , Takeda Haruhiko , Marui Saiko , Okada Hirokazu , Hirano Tomonori , Kuwada Takeshi , Sogabe Yuko , Kakiuchi Nobuyuki , Tomono Teruko , Mima Atsushi , Morita Toshihiro , Ueda Tatsuki , Tsuda Motoyuki , Yamauchi Yuki , Kuriyama Katsutoshi , Sakuma Yojiro , Ota Yuji , Maruno Takahisa , Uza Norimitsu , Marusawa Hiroyuki , Kageyama Ryoichiro , Chiba Tsutomu , Seno Hiroshi
Published: March 2023

PDC formation in Albcre; Hes1flox/flox and control mice with or without DDC diet.
Fig. S3 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma
Authors: Matsumori Tomoaki , Kodama Yuzo , Takai Atsushi , Shiokawa Masahiro , Nishikawa Yoshihiro , Matsumoto Tomonori , Takeda Haruhiko , Marui Saiko , Okada Hirokazu , Hirano Tomonori , Kuwada Takeshi , Sogabe Yuko , Kakiuchi Nobuyuki , Tomono Teruko , Mima Atsushi , Morita Toshihiro , Ueda Tatsuki , Tsuda Motoyuki , Yamauchi Yuki , Kuriyama Katsutoshi , Sakuma Yojiro , Ota Yuji , Maruno Takahisa , Uza Norimitsu , Marusawa Hiroyuki , Kageyama Ryoichiro , Chiba Tsutomu , Seno Hiroshi
Published: March 2023

Relative mRNA expression levels of downstream effectors of Notch signaling in the liver tissues of 8-week-old Albcre and Albcre; RosaNotchOE/+ mice.
Fig. S1 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma
Authors: Matsumori Tomoaki , Kodama Yuzo , Takai Atsushi , Shiokawa Masahiro , Nishikawa Yoshihiro , Matsumoto Tomonori , Takeda Haruhiko , Marui Saiko , Okada Hirokazu , Hirano Tomonori , Kuwada Takeshi , Sogabe Yuko , Kakiuchi Nobuyuki , Tomono Teruko , Mima Atsushi , Morita Toshihiro , Ueda Tatsuki , Tsuda Motoyuki , Yamauchi Yuki , Kuriyama Katsutoshi , Sakuma Yojiro , Ota Yuji , Maruno Takahisa , Uza Norimitsu , Marusawa Hiroyuki , Kageyama Ryoichiro , Chiba Tsutomu , Seno Hiroshi
Published: March 2023

Comparison of Albcre; Hes1flox/flox and control mice in liver development.
Supplementary Figures and Table with legends from Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma
Authors: Mottini Carla , Tomihara Hideo , Carrella Diego , Lamolinara Alessia , Iezzi Manuela , Huang Justin K. , Amoreo Carla A. , Buglioni Simonetta , Manni Isabella , Robinson Frederick S. , Minelli Rosalba , Kang Ya'an , Fleming Jason B. , Kim Michael P. , Bristow Christopher A. , Trisciuoglio Daniela , Iuliano Antonella , Del Bufalo Donatella , Di Bernardo Diego , Melisi Davide , Draetta Giulio F. , Ciliberto Gennaro , Carugo Alessandro , Cardone Luca
Published: March 2023

Supplementary Figures and Table with legends
Supplementary Figure 5 from CKAP2L Promotes Non–Small Cell Lung Cancer Progression through Regulation of Transcription Elongation
Authors: Monteverde Tiziana , Sahoo Sudhakar , La Montagna Manuela , Magee Peter , Shi Lei , Lee Dave , Sellers Robert , Baker Alexander R. , Leong Hui Sun , Fassan Matteo , Garofalo Michela
Published: March 2023

Effect of CKAP2L depletion on RNA Pol II distribution
Supplementary Data from MAP3K7-IKK Inflammatory Signaling Modulates AR Protein Degradation and Prostate Cancer Progression
Authors: Huang Zhenlin , Tang Bo , Yang Yinhui , Yang Zhaogang , Shi Lei , Bai Yang , Yan Binyuan , Karnes R. Jeffrey , Zhang Jun , Jimenez Rafael , Wang Liguo , Wei Qiang , Yang Jinjian , Xu Wanhai , Jia Zhankui , Huang Haojie
Published: March 2023

Supplementary Materials and Methodsï¼Œ Supplementary Figure S1-S5, Supplementary Table S1-S2
Supplementary Figures from Inhibition of ATM Induces Hypersensitivity to Proton Irradiation by Upregulating Toxic End Joining
Authors: Zhou Qin , Howard Michelle E. , Tu Xinyi , Zhu Qian , Denbeigh Janet M. , Remmes Nicholas B. , Herman Michael G. , Beltran Chris J. , Yuan Jian , Greipp Patricia T. , Boughey Judy C. , Wang Liewei , Johnson Neil , Goetz Matthew P. , Sarkaria Jann N. , Lou Zhenkun , Mutter Robert W.
Published: March 2023

Suppl. Figures 1-5. Supplemental Figure 1. Increased engagement of resection machinery and delayed repair following proton Bragg peak-induced DNA damage. Supplemental Figure 2. DNApk inhibition does not enhance the relative efficacy of proton Bragg peak irradiation. Supplemental Figure 3. Proton Bragg peak irradiation does not enhance the relative efficacy of proton Bragg peak irradiation on XRCC4 and LIG4 deficient tumor cells. Supplemental Figure 4. LIG4 knockdown attenuates ATM inhibitor-induced RBE enhancement of Bragg peak irradiation. Supplemental Figure 5. Loss of BRCA2 and RAD51 enhances the RBE of proton Bragg peak irradiation.
Table S2 from Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma
Authors: Chen Lixing , Zhai Yali , Wang Yisheng , Fearon Eric R. , Núñez Gabriel , Inohara Naohiro , Cho Kathleen R.
Published: March 2023

OTU abundance
Figure S6 from Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic Melanoma
Authors: Zerhouni Marwa , Martin Anthony R. , Furstoss Nathan , Gutierrez Vincent S. , Jaune Emilie , Tekaya Nedra , Beranger Guillaume E. , Abbe Patricia , Regazzetti Claire , Amdouni Hella , Driowya Mohsine , Dubreuil Patrice , Luciano Frédéric , Jacquel Arnaud , Tulic Meri K. , Cluzeau Thomas , O'Hara Brendan P. , Ben-Sahra Issam , Passeron Thierry , Benhida Rachid , Robert Guillaume , Auberger Patrick , Rocchi Stéphane
Published: March 2023

Supplemental Figure 6
Supplementary Table 3 from Host-Dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors
Authors: Haga Yuya , Marrocco Ilaria , Noronha Ashish , Uribe Mary Luz , Nataraj Nishanth Belugali , Sekar Arunachalam , Drago-Garcia Diana , Borgoni Simone , Lindzen Moshit , Giri Suvendu , Wiemann Stefan , Tsutsumi Yasuo , Yarden Yosef
Published: March 2023

Supplementary Excel File 3
Supplementary Data from A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility
Authors: Emami Nima C. , Cavazos Taylor B. , Rashkin Sara R. , Cario Clinton L. , Graff Rebecca E. , Tai Caroline G. , Mefford Joel A. , Kachuri Linda , Wan Eunice , Wong Simon , Aaronson David , Presti Joseph , Habel Laurel A. , Shan Jun , Ranatunga Dilrini K. , Chao Chun R. , Ghai Nirupa R. , Jorgenson Eric , Sakoda Lori C. , Kvale Mark N. , Kwok Pui-Yan , Schaefer Catherine , Risch Neil , Hoffmann Thomas J. , Van Den Eeden Stephen K. , Witte John S.
Published: March 2023

Figure S1-S6, Table S1-S10
S Table 5 from Sleeping Beauty Transposon Mutagenesis Identifies Genes Driving the Initiation and Metastasis of Uterine Leiomyosarcoma
Authors: Kodama Michiko , Shimura Hiroko , Tien Jean C. , Newberg Justin Y. , Kodama Takahiro , Wei Zhubo , Rangel Roberto , Yoshihara Kosuke , Kuruma Airi , Nakae Aya , Hashimoto Kae , Sawada Kenjiro , Kimura Tadashi , Jenkins Nancy A. , Copeland Neal G.
Published: March 2023

Supplementary Table 5
S Table 4 from Sleeping Beauty Transposon Mutagenesis Identifies Genes Driving the Initiation and Metastasis of Uterine Leiomyosarcoma
Authors: Kodama Michiko , Shimura Hiroko , Tien Jean C. , Newberg Justin Y. , Kodama Takahiro , Wei Zhubo , Rangel Roberto , Yoshihara Kosuke , Kuruma Airi , Nakae Aya , Hashimoto Kae , Sawada Kenjiro , Kimura Tadashi , Jenkins Nancy A. , Copeland Neal G.
Published: March 2023

Supplementary Table 4
Supplementary Data from Mutated SPOP E3 Ligase Promotes 17βHSD4 Protein Degradation to Drive Androgenesis and Prostate Cancer Progression
Authors: Shi Lei , Yan Yuqian , He Yundong , Yan Binyuan , Pan Yunqian , Orme Jacob J. , Zhang Jun , Xu Wanhai , Pang Jun , Huang Haojie
Published: March 2023

Supplementary information and figures
Supplementary Table S2 from YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7
Authors: Pi Jingnan , Wang Wen , Ji Ming , Wang Xiaoshuang , Wei Xueju , Jin Jing , Liu Tao , Qiang Jiaqi , Qi Zhihong , Li Feng , Liu Yue , Ma Yanni , Si Yanmin , Huo Yue , Gao Yufeng , Chen Yiying , Dong Lei , Su Rui , Chen Jianjun , Rao Shuan , Yi Ping , Yu Shuyang , Wang Fang , Yu Jia
Published: March 2023

Primers used in this study. Related to Figure 4, Figure5 and Figure6.
Supplementary Table S1 from YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7
Authors: Pi Jingnan , Wang Wen , Ji Ming , Wang Xiaoshuang , Wei Xueju , Jin Jing , Liu Tao , Qiang Jiaqi , Qi Zhihong , Li Feng , Liu Yue , Ma Yanni , Si Yanmin , Huo Yue , Gao Yufeng , Chen Yiying , Dong Lei , Su Rui , Chen Jianjun , Rao Shuan , Yi Ping , Yu Shuyang , Wang Fang , Yu Jia
Published: March 2023

The clinical data of the patients.
Supplementary Figure S7 from YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7
Authors: Pi Jingnan , Wang Wen , Ji Ming , Wang Xiaoshuang , Wei Xueju , Jin Jing , Liu Tao , Qiang Jiaqi , Qi Zhihong , Li Feng , Liu Yue , Ma Yanni , Si Yanmin , Huo Yue , Gao Yufeng , Chen Yiying , Dong Lei , Su Rui , Chen Jianjun , Rao Shuan , Yi Ping , Yu Shuyang , Wang Fang , Yu Jia
Published: March 2023

YTHDF1 regulates FZD7 and β-catenin.
Figure S1 from MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma
Authors: Krenz Bastian , Gebhardt-Wolf Anneli , Ade Carsten P. , Gaballa Abdallah , Roehrig Florian , Vendelova Emilia , Baluapuri Apoorva , Eilers Ursula , Gallant Peter , D'Artista Luana , Wiegering Armin , Gasteiger Georg , Rosenfeldt Mathias T. , Bauer Stefan , Zender Lars , Wolf Elmar , Eilers Martin
Published: March 2023

Characterization of MYC function in KPC cells.
Table S6 from miR-766-5p Targets Super-Enhancers by Downregulating CBP and BRD4
Authors: Gen Yasuyuki , Muramatsu Tomoki , Inoue Jun , Inazawa Johji
Published: March 2023

Table S6
Table S2 from Circ0008399 Interaction with WTAP Promotes Assembly and Activity of the m6A Methyltransferase Complex and Promotes Cisplatin Resistance in Bladder Cancer
Authors: Wei Wenjie , Sun Jiayin , Zhang Hui , Xiao Xingyuan , Huang Chao , Wang Liang , Zhong He , Jiang Yangkai , Zhang Xiaoping , Jiang Guosong
Published: March 2023

WTAP, METTL3 and METTL14 correlated genes from TCGA database
Supplementary Data from miR-766-5p Targets Super-Enhancers by Downregulating CBP and BRD4
Authors: Gen Yasuyuki , Muramatsu Tomoki , Inoue Jun , Inazawa Johji
Published: March 2023

Supplementary Figures
Figure S2 from Circ0008399 Interaction with WTAP Promotes Assembly and Activity of the m6A Methyltransferase Complex and Promotes Cisplatin Resistance in Bladder Cancer
Authors: Wei Wenjie , Sun Jiayin , Zhang Hui , Xiao Xingyuan , Huang Chao , Wang Liang , Zhong He , Jiang Yangkai , Zhang Xiaoping , Jiang Guosong
Published: March 2023

The m6A modification of TNFAIP3 mRNA and its expression are regulated by circ0008399 and WTAP.
Figure S5 from Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex
Authors: Kovalenko Andrii , Sanin Andres , Kosmas Kosmas , Zhang Long , Wang Ji , Akl Elie W. , Giannikou Krinio , Probst Clemens K. , Hougard Thomas R. , Rue Ryan W. , Krymskaya Vera P. , Asara John M. , Lam Hilaire C. , Kwiatkowski David J. , Henske Elizabeth P. , Filippakis Harilaos
Published: March 2023

Lipidomic analysis of ritanserin treated Tsc2-deficient cells
Figure S4 from Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex
Authors: Kovalenko Andrii , Sanin Andres , Kosmas Kosmas , Zhang Long , Wang Ji , Akl Elie W. , Giannikou Krinio , Probst Clemens K. , Hougard Thomas R. , Rue Ryan W. , Krymskaya Vera P. , Asara John M. , Lam Hilaire C. , Kwiatkowski David J. , Henske Elizabeth P. , Filippakis Harilaos
Published: March 2023

Purine metabolism following ritanserin treatment in Tsc2-deficient cells
Figure S2 from Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex
Authors: Kovalenko Andrii , Sanin Andres , Kosmas Kosmas , Zhang Long , Wang Ji , Akl Elie W. , Giannikou Krinio , Probst Clemens K. , Hougard Thomas R. , Rue Ryan W. , Krymskaya Vera P. , Asara John M. , Lam Hilaire C. , Kwiatkowski David J. , Henske Elizabeth P. , Filippakis Harilaos
Published: March 2023

Gene expression of DGKs and pentose phosphate pathway genes.
Supplementary Data from Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models
Authors: Quiros-Gonzalez Isabel , Tomaszewski Michal R. , Golinska Monika A. , Brown Emma , Ansel-Bollepalli Laura , Hacker Lina , Couturier Dominique-Laurent , Sainz Rosa M. , Bohndiek Sarah E.
Published: March 2023

Supplementary Data from Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models
Table S5 from CstF64-Induced Shortening of the BID 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with ZFP36L2
Authors: Lin Ai , Ji Ping , Niu Xiangjie , Zhao Xuan , Chen Yamei , Liu Weiling , Liu Yachen , Fan Wenyi , Sun Yanxia , Miao Chuanwang , Zhang Shaosen , Tan Wen , Lin Dongxin , Wagner Eric J. , Wu Chen
Published: March 2023

Correlations between PDUI of BID and expression of CPA members in Chang ESCC dataset
Supplementary Table S1 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
Authors: Huggins Danielle N. , LaRue Rebecca S. , Wang Ying , Knutson Todd P. , Xu Yingzheng , Williams Jesse W. , Schwertfeger Kathryn L.
Published: March 2023

Table S1 shows the classification of the macrophage clusters identified by scRNA-seq.
Supplementary Data from ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth
Authors: Ma Wai Kit , Voss Dillon M. , Scharner Juergen , Costa Ana S.H. , Lin Kuan-Ting , Jeon Hyun Yong , Wilkinson John E. , Jackson Michaela , Rigo Frank , Bennett C. Frank , Krainer Adrian R.
Published: March 2023

Supplementary Data from ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth
Supplementary Figures from Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer
Authors: Chang Antao , Liu Liang , Ashby Justin M. , Wu Dan , Chen Yanan , O'Neill Stacey S. , Huang Shan , Wang Juan , Wang Guanwen , Cheng Dongmei , Tan Xiaoming , Petty W.J. , Pasche Boris C. , Xiang Rong , Zhang Wei , Sun Peiqing
Published: March 2023

Supplementary Figures
Supplementary Data from Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
Authors: Devin Julie , Cañeque Tatiana , Lin Yea-Lih , Mondoulet Lucie , Veyrune Jean-Luc , Abouladze Matthieu , Garcia De Paco Elvira , Karmous Gadacha Ouissem , Cartron Guillaume , Pasero Philippe , Bret Caroline , Rodriguez Raphaël , Moreaux Jerome
Published: March 2023

Supplementary Data from Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
Supplementary Data from Hypoxia Promotes Breast Cancer Cell Growth by Activating a Glycogen Metabolic Program
Authors: Tang Ke , Zhu Liyan , Chen Jie , Wang Dianheng , Zeng Liping , Chen Chen , Tang Liang , Zhou Li , Wei Keke , Zhou Yabo , Lv Jiadi , Liu Yuying , Zhang Huafeng , Ma Jingwei , Huang Bo
Published: March 2023

Figure S1-7, Table S1
Supplementary Data from Fam20C Regulates Bone Resorption and Breast Cancer Bone Metastasis through Osteopontin and BMP4
Authors: Zuo Hao , Yang Dengbao , Wan Yihong
Published: March 2023

Supplementary Data
Supplementary Figure from Somatic Mutations Enriched in Cis-Regulatory Elements Affect Genes Involved in Embryonic Development and Immune System Response in Neuroblastoma
Authors: Lasorsa Vito Alessandro , Montella Annalaura , Cantalupo Sueva , Tirelli Matilde , de Torres Carmen , Aveic Sanja , Tonini Gian Paolo , Iolascon Achille , Capasso Mario
Published: March 2023

Supplementary Figure from Somatic Mutations Enriched in Cis-Regulatory Elements Affect Genes Involved in Embryonic Development and Immune System Response in Neuroblastoma
Supplementary Data from Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer
Authors: Hua Xu , Li Yongsheng , Pentaparthi Sairahul R. , McGrail Daniel J. , Zou Raymond , Guo Li , Shrawat Aditya , Cirillo Kara M. , Li Qing , Bhat Akshay , Xu Min , Qi Dan , Singh Ashok , McGrath Francis , Andrews Steven , Aung Kyaw Lwin , Das Jishnu , Zhou Yunyun , Lodi Alessia , Mills Gordon B. , Eckhardt S. Gail , Mendillo Marc L. , Tiziani Stefano , Wu Erxi , Huang Jason H. , Sahni Nidhi , Yi S. Stephen
Published: March 2023

Supplementary Table S7
Supplementary Data from Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer
Authors: Hua Xu , Li Yongsheng , Pentaparthi Sairahul R. , McGrail Daniel J. , Zou Raymond , Guo Li , Shrawat Aditya , Cirillo Kara M. , Li Qing , Bhat Akshay , Xu Min , Qi Dan , Singh Ashok , McGrath Francis , Andrews Steven , Aung Kyaw Lwin , Das Jishnu , Zhou Yunyun , Lodi Alessia , Mills Gordon B. , Eckhardt S. Gail , Mendillo Marc L. , Tiziani Stefano , Wu Erxi , Huang Jason H. , Sahni Nidhi , Yi S. Stephen
Published: March 2023

Supplementary Table S8