bluuebunny/crossref_metadata_2025 huggingface dataset:
Construindo a qualidade social da escola pública
Authors: Bertagna Regiane Helena , Sordi Mara Regina Lemes de , Lara Rosangela de Souza Bittencourt
Published: June 2024

Este artigo apresenta indicadores de qualidade identificados a partir das contribuições dos alunos do Ensino Fundamental das escolas públicas de um município do interior do estado de São Paulo/Brasil, além de resgatar e buscar fortalecer a participação estudantil no debate sobre a qualidade social da escola pública. Para tanto recorreu-se à pesquisa de abordagem qualitativa com base nas respostas de 1.129 alunos do 9º ano do Ensino Fundamental a um questionário com perguntas abertas e, posteriormente, na participação de 40 alunos em uma oficina sobre qualidade da escola pública. A análise e agrupamentos dos dados coletados foram organizados a partir das proposições de Bardin (2009). Segundo os alunos participantes, os aspectos que colaboram para a qualidade social envolvem determinantes externos: infraestrutura, alimentação e financiamento; e internos: práticas pedagógicas, organização do trabalho pedagógico, valores, relações interpessoais, comportamento. Os relatos dos alunos permitiram compreender a sua perspectiva sobre a qualidade da escola e indicaram a potencialidade de suas contribuições quando convidados a participar de processos democráticos que ampliam sua formação para além dos conhecimentos cognitivos exigidos em avaliações em larga escala, possibilitando o desenvolvimento de outras dimensões da formação humana.
Leitura literária e experiência
Authors: Ayres Isabel Gomes , Henning Paula Corrêa
Published: June 2024

O presente artigo almeja estreitar de que modo a leitura literária pode catalisar uma educação pela experiência. Para tanto, aciona como ferramenta teórico-metodológica a problematização a partir dos estudos de Michel Foucault (2006). A escrita do artigo é desenvolvida em três momentos. No primeiro momento, embasando-se nos apontamentos de Jorge Larrosa (2009, 2011, 2016), acerca-se do conceito de experiência e atenta para aquilo que pode impedi-la. No segundo momento, debruça-se sobre estudos empreendidos por Michel Foucault (2009, 2010, 2013) para tensionar a experiência como aquilo que tanto pode constituir o sujeito quanto dessubjetivá-lo. Por fim, estabelece-se um diálogo com obras produzidas pelos dois filósofos mencionados, atentando-se para a potência que abriga a leitura literária de catalisar experiências em quem lê. O exercício de pensamento a que este artigo se propõe é fortalecido pelas interlocuções que nele se estabelecem entre os referenciais filosóficos e as obras literárias de diferentes gêneros e épocas. Espera-se que a escrita deste artigo encontre outros professores e pesquisadores do campo educacional, provocando-os a aliarem-se à filosofia e à literatura na invenção de modos outros de pensar e de vivenciar a educação que não apenas pelo cientificismo.
Ensino jurídico e literatura
Authors: Abreu Leonardo Lani de , Chagas Isabelly Krystal Souza , Araújo Marcos Vinícius Silva de
Published: June 2024

A partir do pressuposto de que a literatura é um componente elementar à formação dos estudantes do direito, por desenvolver competências como a criatividade, a capacidade crítica e reflexiva, o senso ético e de justiça, a empatia e a habilidade comunicativa, imprescindíveis à prática profissional, sugere-se o diálogo teórico entre as categorias descritas por Ost (2004) — Direito na Literatura e Direito como Literatura — e Cândido (2023) — Direito à Literatura — e a periodização das correntes jusfilosóficas proposta por Cassien e Billier (2005). Na parte referente ao Direito na Literatura, enumeram-se algumas obras literárias fictícias que podem contribuir para lançar luzes sobre algumas questões jurídicas, dada a sua proximidade com o tema. Em o Direito como Literatura, é analisado como o emprego de recursos típicos da literatura tem sido uma resposta eficaz à crise sofrida pelo positivismo jurídico ao longo do século XX e que adentrou no século XXI. Postula-se que a utilização da literatura nos cursos de Direito pode atenuar a aridez de determinados conteúdos, facilitando sua assimilação. Argumenta-se também que o desenvolvimento do prazer pela leitura entre os juristas pode ajudar a mitigar práticas positivistas ainda reinantes, que são um entrave à plena concretização dos direitos dos cidadãos.
Sensitivity and strength of maize roots facing different physical conditions of the growth medium
Authors: Śróbka Joanna , Potocka Izabela , Karczewski Jerzy , Szymanowska-Pułka Joanna
Published: June 2024

The morphology of a plant's root is strongly affected by the compaction of the growth medium, the size of its particles, or the presence of non-movable obstacles. However, little is known about the effect of these characteristics on root anatomy and mechanical properties of the root tissues. Anatomical features of maize roots grown in media that varied in density and/or structure (soil, glass beads, vermiculite) were analyzed on cross-sections through the elongation and maturation zones of the roots of 14-day-old seedlings. The sections were stained for lignin and suberin to recognize the developmental stages of exodermis and endodermis. Cortex thickness, number of cortical cell layers, and diameter of the vascular cylinder (stele) were measured in both zones. The Young's modulus of the roots was determined using mechanical tensile tests. Assuming that the root can be considered a composite material, a model was used that allowed, for the first time, to estimate the mechanical properties of the stele and cortex.
While the cell arrangement of roots grown in a medium with high density and fine movable particles (soil) was regular, roots grown in a medium with low density and light particles (vermiculite) and a medium with high density and large unmovable particles (glass beads) showed early damage of the rhizodermis and impaired cell arrangement in the cortex and vascular cylinder. In these roots, the exodermis and endodermis matured closer to the root tip than in roots from the soil. The vermiculite roots were the most outliers regarding morphometric parameters and mechanical properties. The Young's modulus of the stele was many times greater than the Young's modulus of the cortex in the roots of all variants. Of the media used in the experiment, the soil appears to be most favorable for the maize root growth and development.
Cost and cost-effectiveness of BPaL regimen used in drug-resistant TB treatment in the Philippines
Authors: Evans D. , Hirasen K. , Casalme D.J. , Gler M.T. , Gupta A. , Juneja S.
Published: June 2024

BACKGROUND
In 2022, the WHO announced that the 6-month BPaL/M regimen should be used for drug-resistant TB (DR-TB). We estimate the patient and provider costs of BPaL compared to current standard-of-care treatment in the Philippines.

METHODS
Patients
on BPaL under operational research, or 9–11-month standard short oral regimen (SSOR) and 18–21-month standard long oral regimen (SLOR) under programmatic conditions were interviewed using the WHO cross-sectional TB patient cost tool. Provider costs were assessed through a bottom-up
and top-down costing analysis.

RESULTS
Total patient costs per treatment episode were lowest with BPaL (USD518.0) and increased with use of SSOR (USD825.8) and SLOR (USD1,023.0). Total provider costs per successful treatment were lowest with
BPaL (USD1,994.5) and increased with SSOR (USD3,121.5) and SLOR (USD10,032.4). Compared to SSOR, BPaL treatment was cost-effective at even the lowest willingness to pay threshold. As expected, SLOR was the costliest and least effective regimen.

CONCLUSIONS
Costs
incurred by patients on BPaL were 37% (95% CI 22–56) less than SSOR and 50% (95% CI 32–68) less than SLOR, while providers could save 36% (95% CI 21–56) to 80% (95% CI 64–93) per successful treatment, respectively. The study shows that treatment of DR-TB with BPaL was
cost-saving for patients and cost-effective for the health system.
Preço da cesta básica no município de Eirunepé – AM
Authors: Silva Tarcísio Roberto Cavalcante da , Medrado Sara dos Santos , Melo Jhénniffer Menezes de
Published: June 2024

Considerando a importância da alimentação como base da vida humana, o presente estudo teve por objetivo geral pesquisar os preços dos itens componentes da cesta básica no município de Eirunepé-AM ao longo de doze meses, sendo os itens alimentícios definidos com base na Pesquisa Nacional da Cesta Básica de Alimentos – PNCBA, com adaptações à realidade local. Para o alcance do objetivo proposto, foi realizada uma pesquisa de campo, de cunho quantitativo, entre os meses de setembro de 2021 e agosto de 2022. O objetivo principal foi alcançado por meio da coleta mensal de preços em estabelecimentos comerciais em cada um dos seis bairros oficiais da cidade, o que possibilitou extrair dados estatísticos como menor preço, maior preço e preço médio praticado entre os comércios pesquisados durante o período de tempo estabelecido. Mensalmente, após a coleta e tabulação dos dados, estes eram divulgados por meio de um banner digital para os aplicativos Whatsapp e Instagram, juntamente com uma breve análise, buscando informar a sociedade local sobre as diferenças e alterações de preço entre os itens, o que pôde possibilitar uma visão do panorama referente ao custo da alimentação em Eirunepé – AM ao longo de um ano. Além disso, as informações divulgadas também criaram condições para que o cidadão eirunepeense pudesse economizar nas compras de alimentos, algo tão importante em meio a um cenário de escalada nos preços dos itens alimentícios.
A produção textual na escola: as dificuldades dos alunos das turmas de 7ª e 8ª série da escola municipal “Antonio Correa de Lima” em Vila de Nova Palestina em produzir textos coesos e coerentes
Authors: Costa Vanda Ester Lira , Rodrigues Anderson Alexandre
Published: June 2024

Este artigo aborda as dificuldades que os alunos da turma de 7ª e 8ª série do Ensino Fundamental da Escola Municipal “Antonio Correa de Lima” localizada em vila Palestina, município de Nova Esperança do Piriá-PA, apresentam em produzir textos. A produção textual é uma atividade cognitiva e social. Envolve não somente a ativação das ações cognitivas, mas os aspectos relativos às condições de produção de textos. A pesquisa realizou-se no ano de 2010, com o objetivo de analisar quais as dificuldades dos discentes em produzir textos. De modo específico investigar o porquê de os alunos terem essas dificuldades no momento da produção textual. Objetiva-se com esta pesquisa estar contribuindo para uma releitura do trabalho pedagógico que está sendo desenvolvido na escola, dando subsídios ao professor para a análise e discussão de todo processo de aprendizagem da escrita. Em suma, tenta-se apontar que recursos faltam aos alunos do Ensino Fundamental para que possam ser proficientes na produção de textos escritos. Utilizou-se como proposta metodológica um estudo bibliográfico e a pesquisa de campo empírico com base em teóricos como Bakhtin (2002), Marcuschi (2002), Koch (1997), Travaglia (1991), e outros. O instrumento utilizado para a coleta de dados foi o Gênero Textual Causos Populares.
Criação e implementação de currículos escolares interculturais para comunidades Indígenas na Floresta Amazônica
Authors: Gonçalves Maurilho de Lima , Oliveira Kleberson de , Parente Ednei Pereira
Published: June 2024

A criação e implementação de currículos escolares interculturais para comunidades indígenas na floresta amazônica são essenciais para promover uma educação que valorize a diversidade cultural e preserve as tradições indígenas. Este estudo justifica-se pela necessidade de compreender como esses currículos podem ser desenvolvidos e aplicados de maneira eficaz, respeitando as especificidades culturais das comunidades indígenas. Os objetivos do estudo incluem analisar os conceitos de interculturalidade na educação indígena, investigar as práticas de desenvolvimento e implementação de currículos interculturais, identificar desafios e explorar inovações na área. A pesquisa foi realizada por meio de uma revisão bibliográfica, utilizando bases de dados como PubMed e SciELO. Os resultados destacam a importância da participação ativa das comunidades indígenas no processo educativo, a formação adequada de professores e a criação de materiais didáticos culturalmente relevantes. A conclusão aponta que, apesar dos desafios, a educação intercultural é uma estratégia fundamental para promover uma educação inclusiva e respeitosa das diversidades culturais, respondendo à pergunta de pesquisa sobre as melhores práticas na criação e implementação de currículos interculturais.
Optimal design of LiMn2O4 for high-rate applications by means of citric acid aided route and microwave heating
Authors: Shmatok Yurii , Potapenko Hanna , Kirillov Sviatoslav
Published: June 2024

Due to shortening the duration of the process and possibility to obtain crystals of smaller and uniform size, microwave heating is considered an effective and promising tool for the synthesis of LiMn2O4, a valuable cathode material for lithium-ion batteries. However, electrochemical characteristics of LiMn2O4 obtained with its help are almost completely absent and do not allow for drawing a sound conclusion regarding advantages and drawbacks of microwave processing. Here we present a description of the microwave-assisted citric acid aided synthesis, characterization and electrochemical performance of LiMn2O4. The disclosure of detailed working protocols enabling one to manufacture samples tolerant to extremely high currents is the main novelty of this paper. Specifically, our material sustains current loads up to 40 C (5920 mA g-1) and completely recovers after cycling at harsh conditions.
Evaluación de técnicas de inteligencia artificial para predicción de señales de electrocardiograma. Guayaquil. Ecuador. 2023
Authors: Noboa-Terán Cesar Augusto , Ramirez-Hecksher Ana María , Medina-Avelino Jorge Alberto
Published: June 2024

Las enfermedades cardiovasculares son trastornos del corazón y de los vasos sanguíneos. Su mortalidad es alta y cada año fallecen casi 18 millones de personas en el mundo.   El electrocardiograma es usado en medicina para monitorear pequeños cambios eléctricos en la piel del cuerpo de un paciente, emitidos por la actividad del corazón humano. En la actualidad  con los  avances tecnológicos y la evolución de los algoritmos de inteligencia artificial, se  pueden  aprovechar las diferentes técnicas de inteligencia artificial, para el análisis de señales de un electrocardiograma, para predecir una patología cardíaca y determinar qué algoritmo es el más adecuado, en la predicción del diagnóstico de una alteración presente.
Objetivo: Probar algoritmos de inteligencia artificial y evaluar su aplicación en  la predicción de patologías cardiacas, a través de la introducción de información de electrocardiogramas, en la base de datos abierta de arritmias de MIT-BIH, para visibilizar su utilidad predictiva  para alteraciones  cardiacas en el ámbito de la medicina.
Material y Método. El estudio se  realiza en la Facultad de Ciencias Médicas de la Universidad de Guayaquil, utiliza técnicas de inteligencia artificial para el análisis de señales ECG de la base de datos abierta de arritmias de MIT-BIH.
Conclusión.  La evolución de los algoritmos de inteligencia artificial, permiten abordarla  en el ámbito de la medicina, para  monitorear si es  posible  predecir eventos cardiacos que complican la salud de  los  pacientes.
POSSIBILIDADES DE SE ABORDAR RECORRÊNCIA MATEMÁTICA NO ENSINO MÉDIO
Authors: Oliveira Carlos Alexandre Santana , Freire Francielck Domingos
Published: June 2024

Este trabalho tem como objetivo apresentar as possíveis aplicações da recorrência matemática de primeira ordem na modelagem de problemas que envolvem padrões, sejam eles numéricos ou geométricos. Sabe-se que na maioria dos livros didáticos de matemática utilizados nas escolas públicas brasileiras, os autores geralmente abordam as aplicações relacionadas ao conteúdo da componente curricular no início e no final de cada capítulo. De certa forma, tais abordagens favorecem a compreensão dos assuntos tratados e ainda levam o aluno a conhecer as diversas aplicações da matemática. Várias dessas aplicações envolvem modelagem matemática e, em muitos casos, a obtenção do modelo que representa o fenômeno ocorre mediante a descoberta de padrões. A partir da existência de padrões, o modelo matemático pode ser obtido por meio de técnicas recursivas. Assim, o estudo contribui para uma compreensão adequada de recorrência matemática de primeira ordem e permite ampliar a discussão sobre as inúmeras possibilidades de chegar à solução de um dado problema, motivando o debate e possibilitando pesquisas futuras.
Perancangan Sistem Informasi Manajemen Proyek C’HeTi: Cultural Heritage Technology Virtual Tour Guide Berbasis Mobile
Authors: Galasca Syafhira Ananda , Yahfizham Yahfizham
Published: June 2024

Sumatera Utara menjadi salah satu daerah wisata favorit baik bagi wisatawan Lokal maupun Mancanegara. jumlah wisatawan yang berkunjung ke Sumatera Utara terus meningkat sepanjang tahun 2023, khususnya wisatawan Mancanegara. Badan Pusat Statistik (BPS) Sumatera Utara (SUMUT) menyatakan bahwa jumlah wisatawan asing yang berkunjung ke Sumatera Utara meningkat sebanyak 164,46% dibandingkan tahun sebelumnya. Meskipun demikian, kurang lengkapnya informasi mengenai tempat wisata masih tidak bisa dihindari. hal ini dapat berakibat pada kurang nya kepuasan wisatawan terhadap kawasan wisata. Masalah lainnya yakni mahalnya jasa tour guide yang tersedia pada Kawasan wisata. Oleh karena itu diperlukan adanya aplikasi yang dapat memberikan pengalaman Virtual Tour sekaligus Tour Guide agar mempermudah para wisatawan yg hendak berkunjung ke daerah wisata tertentu. C’HeTi merupakan aplikasi berbasis mobile yang melibatkan pencarian tempat wisata, kultur lokal wisata dan teknologi yang bertujuan untuk mempermudah wisatawan Ketika hendak mengunjungi tempat wisata. Penelitian ini menggunakan metode Rapid Application Development (RAD) sebagai metode pengembangan nya. Dimana metode ini berfokus pada pengembangan software (perangkat lunak) dalam waktu yang singkat.  Aplikasi ini diharapkan dapat membantu wisatawan sekaligus menjadikan pengalaman wisata yang mudah dan menyenangkan sekaligus dapat terus meningkatkan grafik wisatawan lokal maupun mancanegara di Sumatera Utara.
Confidential Reporting on Structural Safety (CROSS)
Authors: Soane Alastair
Published: June 2024

Director of Structural-Safety, Alastair Soane, summarises the latest CROSS newsletter and encourages readers to submit reports.
Virtual reality: immersed in the structural world
Authors: McCabe Aimee , McPolin Daniel
Published: June 2024

Virtual reality is a rapidly emerging technology, driven by the computer gaming industry. The maturity of the concept, combined with modern hardware, is delivering an experience which offers a useful commercial tool for industry and educators. This article discusses the uses of virtual reality within structural engineering and provides an understanding of how it can be incorporated easily and efficiently for design purposes and beyond.
Managing risk and contractual liability. Part 3: Scope of work
Authors:   Griffiths & Armour
Published: June 2024

The third part of our series from insurance broker Griffiths & Armour explores the problems that can arise from failing to follow a tight brief.
Digital Marketing, Entrepreneurial Orientation, and Business Capital on the Financial Performance of MSMEs in Indonesia
Authors: Yuliastuti Hilda , Putra Johni Eka , Utomo Bekti
Published: June 2024

This study looks into how business capital, entrepreneurial orientation, digital marketing, and the financial performance of Micro, Small, and Medium-Sized Enterprises (MSMEs) in Indonesia interact. The study analyzes data from a diverse sample of 400 MSMEs using Structural Equation Modeling with Partial Least Squares (SEM-PLS) 3 and a quantitative research design. Descriptive statistics shed light on the essential factors and demographic profile, and the measurement model assessment verifies the constructs' validity and reliability. Significantly positive correlations between digital marketing, entrepreneurial orientation, business capital, and financial success are established by the structural model study. The mediating roles of business capital and entrepreneurial orientation are revealed through indirect impacts. R-square values and model fit indices attest to the suggested model's resilience. The results add to our understanding of the variables that influence MSME success in the Indonesian business environment and provide useful information for future research projects, practitioners, and policymakers.
An Analytical Observational Study to Determine the Antibacterial and Antioxidant Properties of Dashapushpam, Ten Medicinal Plants
Authors: Praseetha P.K , Sreedevy K
Published: June 2024

A collection of ten revered herbs known with their traditional and therapeutic significance is known as Dashapushpam in the Kerala state of India, and particularly utilized by Keralites on the onsets of the monsoons. The current research aims to showcase the antibacterial and antioxidant properties of these ten herbs. The antibacterial efficacy was assessed against Gram-negative Escherichia coli and Gram-positive Bacillus subtilis using the agar-gel diffusion method. All extracts exhibited varying degrees of activity against these test organisms, with their effectiveness compared to the standard antibiotic amoxicillin. Additionally, the study evaluated the antioxidant potential of the Dashapushpam herbs through the nitric oxide scavenging assay, revealing different levels of antioxidant activity among the plants. These findings support the potential use of these ten herbs in medicinal applications as anti-infective agents.
EDUCAÇÃO INTEGRAL EM TEMPO INTEGRAL NO ENSINO MÉDIO EM MATO GROSSO:
Authors: Lima Waleska Gonçalves de , Casagrande Ana Lara , Maciel Cristiano
Published: June 2024

Este artigo apresenta práticas relacionadas ao movimento STEAM – Science (Ciência), Tecnology (Tecnologia), Engineering (Engenharia), Art (Arte) e Math (Matemática) – no contexto do Novo Ensino Médio na rede estadual de Mato Grosso. Analisa-se as possibilidades e desafios do movimento STEAM para o engajamento juvenil na educação integral em tempo integral. Por meio do levantamento bibliográfico, documental, aplicação de questionário e análise dos dados via ciclo de políticas, nota-se que se materializam inovações na prática, visando maior envolvimento dos jovens, embora seja preciso considerar a participação do setor privado intitulado sem fins lucrativos na sua operacionalização. A efeito deste artigo, os resultados encontrados apontam que: a maior parte dos sujeitos considera que ocorreram formações específicas na rede estadual sobre o Novo Ensino Médio; parte significativa dos gestores declarou conhecer o movimento STEAM, enquanto o dado dos docentes mostrou que, dos 13 sujeitos, 06 asseveram desconhecê-lo. A maioria identificou que a escola já desenvolveu ou desenvolve alguma ação, atividade ou projeto STEAM e, quanto ao formato, a maioria informou que isso ocorreu por meio de disciplinas eletivas, seguida de projeto interdisciplinar. Lança-se o repto a que se compreenda a sustentação da reforma do Ensino Médio em Mato Grosso.
Minimum 10-year follow-up outcomes of arthroscopic Bankart’s repair with metallic anchors: Reliable results with low redislocation rates
Authors: Gupta Prateek Kumar , Khanna Vishesh , Agrawal Nikunj , Gupta Pratyaksh
Published: June 2024

BACKGROUND

With stiff competition from alternative albeit more expensive counterparts, it has become important to establish the applicability of metallic anchors for shoulder instability in the modern era. This can be accomplished, in part, by analysing long-term outcomes.

AIM

To analyse minimum 10-year outcomes from 30 patients following arthroscopic anterior stabilisation using metallic anchors.

METHODS

Prospectively collected data from arthroscopic Bankart repairs performed using metal anchors during 2007P-2010 were retrospectively analysed in this single-surgeon study. Comprehensive data collection included historical and clinical findings, dislocation details, operative specifics, and follow-up radiological and clinical findings including shoulder scores. The primary outcomes were patient-reported scores (Constant, American Shoulder and Elbow Surgeons [ASES], and Rowe scores) and pain and instability on a visual analogue scale (VAS).

RESULTS

A 3% recurrence rate of dislocation was noted at the final follow-up. Total constant scores at 10 years postoperatively measured between 76 and 100 (mean 89) were significantly better than preoperative scores (mean 62.7). Congruous improvements were also noted in the Rowe and ASES scores and VAS at the 10-year review.

CONCLUSION

Reliable long-term outcomes with metallic anchors in surgery for shoulder instability can be expected. Our results provide additional evidence of their continued, cost-effective presence in the modern scenario.
Japanese candlestick charts for diabetes
Authors: Boj-Carceller Diana
Published: June 2024

Continuous glucose monitoring (CGM) is a popular technology among the diabetic population, especially in patients with type 1 diabetes and those with type 2 diabetes treated with insulin. The American Diabetes Association recommends standardization of CGM reports with visual cues, such as the ambulatory glucose profile. Nevertheless, interpreting this report requires training and time for CGM to be cost-efficient. In this work it has been proposed to incorporate Japanese candlestick charts in glucose monitoring. These graphs are used in price analysis in financial markets and are easier to view. Each candle provides extra information to make prudent decisions since it reports the opening, maximum, minimum and closing glucose levels of the chosen time frame, usually the daily one. The Japanese candlestick chart is an interesting tool to be considered in glucose control. This graphic representation allows identification of glucose trends easily through the colors of the candles and maximum and minimum glucose values.
Digestive and breast cancer patients managed during the first wave of COVID-19 pandemic: Short and middle term outcomes
Authors: Trébol Jacobo , Carabias-Orgaz Ana , Esteban-Velasco María Carmen , García-Plaza Asunción , González-Muñoz Juan Ignacio , Sánchez-Casado Ana Belén , Parreño-Manchado Felipe Carlos , Eguía-Larrea Marta , Alcázar-Montero José Antonio
Published: June 2024

BACKGROUND

The first wave of coronavirus disease 2019 (COVID-19) pandemic in Spain lasted from middle March to the end of June 2020. Spanish population was subjected to lockdown periods and scheduled surgeries were discontinued or reduced during variable periods. In our centre, we managed patients previously and newly diagnosed with cancer. We established a strategy based on limiting perioperative social contacts, preoperative screening (symptoms and reverse transcription-polymerase chain reaction) and creating separated in-hospital COVID-19-free pathways for non-infected patients. We also adopted some practice modifications (surgery in different facilities, changes in staff and guidelines, using continuously changing personal protective equipment…), that supposed new inconveniences.

AIM

To analyse cancer patients with a decision for surgery managed during the first wave, focalizing on outcomes and pandemic-related modifications.

METHODS

We prospectively included adults with a confirmed diagnosis of colorectal, oesophago-gastric, liver-pancreatic or breast cancer with a decision for surgery, regardless of whether they ultimately underwent surgery. We analysed short-term outcomes [30-d postoperative morbimortality and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection] and outcomes after 3 years (adjuvant therapies, oncological events, death, SARS-CoV-2 infection and vaccination). We also investigated modifications to usual practice.

RESULTS

From 96 included patients, seven didn’t receive treatment that period and four never (3 due to COVID-19). Operated patients: 28 colon and 21 rectal cancers; laparoscopy 53.6%/90.0%, mortality 3.57%/0%, major complications 7.04%/25.00%, anastomotic leaks 0%/5.00%, 3-years disease-free survival (DFS) 82.14%/52.4% and overall survival (OS) 78.57%/76.2%. Six liver metastases and six pancreatic cancers: no mortality, one major complication, three grade A/B liver failures, one bile leak; 3-year DFS 0%/33.3% and OS 50.0%/33.3% (liver metastases/pancreatic carcinoma). 5 gastric and 2 oesophageal tumours: mortality 0%/50%, major complications 0%/100%, anastomotic leaks 0%/100%, 3-year DFS and OS 66.67% (gastric carcinoma) and 0% (oesophagus). Twenty breast cancer without deaths/major complications; 3-year OS 100% and DFS 85%. Nobody contracted SARS-CoV-2 postoperatively. COVID-19 pandemic–related changes: 78.2% treated in alternative buildings, 43.8% waited more than 4 weeks, two additional colostomies and fewer laparoscopies.

CONCLUSION

Some patients lost curative-intent surgery due to COVID-19 pandemic. Despite practice modifications and 43.8% delays higher than 4 weeks, surgery was resumed with minimal changes without impacting outcomes. Clean pathways are essential to continue surgery safely.
Simulated patient methodology as a “gold standard” in community pharmacy practice: Response to criticism
Authors: Kunow Christian , Langer Bernhard
Published: June 2024

The simulated patient methodology (SPM) is considered the “gold standard” as covert participatory observation. SPM is attracting increasing interest for the investigation of community pharmacy practice; however, there is criticism that SPM can only show a small picture of everyday pharmacy practice and therefore has limited external validity. On the one hand, a certain design and application of the SPM goes hand in hand with an increase in external validity. Even if, on the other hand, this occurs at the expense of internal validity due to the trade-off situation, the justified criticism of the SPM for investigating community pharmacy practice can be countered.
Non-enzymatic methods for isolation of stromal vascular fraction and adipose-derived stem cells: A systematic review
Authors: Mundluru Vamsi Krishna , Naidu MJ , Mundluru Ravi Teja , Jeyaraman Naveen , Muthu Sathish , Ramasubramanian Swaminathan , Jeyaraman Madhan
Published: June 2024

BACKGROUND

Adipose-derived stem cells (ADSCs) and the stromal vascular fraction (SVF) have garnered substantial interest in regenerative medicine due to their potential to treat a wide range of conditions. Traditional enzymatic methods for isolating these cells face challenges such as high costs, lengthy processing time, and regu-latory complexities.

AIM

This systematic review aimed to assess the efficacy and practicality of non-enzymatic, mechanical methods for isolating SVF and ADSCs, comparing these to conventional enzymatic approaches.

METHODS

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a comprehensive literature search was conducted across multiple databases. Studies were selected based on inclusion criteria focused on non-enzymatic isolation methods for SVF and ADSCs from adipose tissue. The risk of bias was assessed, and a qualitative synthesis of findings was performed due to the methodological heterogeneity of the included studies.

RESULTS

Nineteen studies met the inclusion criteria, highlighting various mechanical techniques such as centrifugation, vortexing, and ultrasonic cavitation. The review identified significant variability in cell yield and viability, and the integrity of isolated cells across different non-enzymatic methods compared to enzymatic procedures. Despite some advantages of mechanical methods, including reduced processing time and avoidance of enzymatic reagents, the evidence suggests a need for optimization to match the cell quality and therapeutic efficacy achievable with enzymatic isolation.

CONCLUSION

Non-enzymatic, mechanical methods offer a promising alternative to enzymatic isolation of SVF and ADSCs, potentially simplifying the isolation process and reducing regulatory hurdles. However, further research is necessary to standardize these techniques and ensure consistent, high-quality cell yields for clinical applications. The development of efficient, safe, and reproducible non-enzymatic isolation methods could significantly advance the field of regenerative medicine.
Safe and Sound: A mixed-methods study to explore relationships between special education classroom practitioners and autistic students through music therapy consultation
Authors: Margetts Lisa
Published: June 2024

This study investigated the accessibility and viability of the Safe and Sound music therapy consultation protocol for classroom practitioners seeking to optimise relationships with students in a UK school providing specialist education for autistic children. Winnicott’s theory of the holding environment provided the framework for an original evaluation instrument, which underpinned an autism-focused staff development programme. Five participants evaluated their usual musical interaction with a student (pre-intervention). Following the development programme (intervention), participants undertook six filmed music sessions with the same individual (post-intervention). Two self-chosen extracts, pre- and post-intervention, were self-rated against the evaluation instrument. Participants then reflected on their experiences in interviews. The same ten randomised video extracts were similarly rated by 18 UK music therapists. Qualitative results evidenced participants’ learning during the study as enabling them to attune to the student and hold them in mind. Quantitative results showed the realisation of this in adaptation to the student through concrete musical skills. The study indicated that Winnicott’s theory of the holding environment could support the optimisation of classroom practitioner-student relationships. The small sample prohibits outcomes generalisation and further research is needed to explore wider protocol viability.
LAW ENFORCEMENT OF ILLEGAL LOBSTER CLEAR SEED DISTRIBUTION CRIME
Authors: Wahyudi Tri , Prawesthi Wahyu , Khoidin M.
Published: June 2024

Indonesia is an archipelago that is rich in flora and fauna both on land and sea. It causes some people to commit criminal acts, especially criminal acts in distributing lobster clear seeds illegally and not fulfilling fisheries licenses in Indonesia. Therefore, serious efforts are needed to tackle these fisheries crimes. The objective of this research is to find out the effectiveness of law enforcement regarding illegal distribution of lobster clear seed; and to observe the law enforcement attempts against its case. The approach method used in this research is juridical normative approach. The juridical normative approach is an approach that uses legislation by examining all laws and regulations related to the legal issues being addressed and conceptual approaches derived from views and doctrines that develop in legal science. The regulation on the prohibition of marketing clear lobster seeds is regulated in the Minister of Marine Affairs and Fisheries Regulation No. 12/PERMEN-KP/2020 concerning the Management of Lobsters, Crabs and Rajungan in the Republic of Indonesia and amended to the Minister of Marine Affairs and Fisheries Regulation No. 17/2021 concerning the Management of Lobsters, Crabs and Rajungan in Indonesian territorial waters.
THE EFFORTS IN PREVENTING ESCAPED PRISONERS AT CORRECTIONAL INSTITUTION CLASS I SURABAYA
Authors: Mustofa Zainal , Esthi Anggrita
Published: June 2024

Polemics over the accuracy of correctional system implementation and the non-conducive environmental impact have triggered violations by prisoners to commit acts of escapes from correctional institutions. The lack of explicit regulation of this act has led to the increasing number of escape attempts made by prisoners. The prisoners’ escape attempts also occurred at the Correctional Institution Class I Surabaya. Therefore, this research was conducted to find out and analyse the efforts and constraints in preventing escape attempts by prisoners. The method of approach used in this research is juridical sociological by examining Law No. 12/1995 on Corrections, Correctional Institution Guarding Regulations of 1975, and Decree of the Director General of Corrections No. E.22.PR.08.03 of 2001 on fixed procedures; and analysing the implementation of security systems in correctional class I Surabaya in actual conditions. There are 2 legal material sources in the research, such as (1) primary data from interviews with the officers of correctional institution class I Surabaya; (2) secondary data from official documents, law books related to the research topic. Preventive and repressive efforts have been implemented by the correctional institution class I Surabaya. However, they have faced several constraints in implementing these efforts, such as over-capacity of inmates, the mismatch between the number of prison staff and inmates, the absence of strict sanctions, and the lack of welfare of correctional institution class I Surabaya staff.
JURIDICAL ANALYSIS BETWEEN LIFE INSURANCE COMPANY AND INDEPENDENT MARKETING OFFICE IN DISTRICT COURT DECISION NUMBER: 661/PDT.G/2021/PN.JKT.SEL
Authors: Puspita Bunga Putri , Razak M. Abdul
Published: June 2024

We need a financial service organisation that assists in managing and planning one’s finances in order to achieve a prosperous life in society. In addition, a fair and transparent agreement is needed in arranging insurance. All companies in the financial services sector including insurance companies must be supervised by Financial Services Authority (OJK) as stipulated in Law No. 40/2014 on insurance. It is conducted to prevent potential fraud that can endanger customers. Therefore this research is conducted to find out and analyse about cooperation agreement procedure between life insurance company and independent marketing office especially the case on District Court Decision Number: 661/Pdt.G/2021/Pn.Jkt.Sel. The type of research used is normative combined with a statutory and case study approach. The research results indicate that an insurance agreement must fulfil the requirements in accordance with Article 1320 BW and the mandatory provisions of the Criminal Code Articles 250-251. Independent marketing offices that cooperate with insurance companies must always be aware in conducting agreements to prevent unwanted force majeure in the future. The legal effect of force majeure is that the defendant cannot fulfil its obligations in the engagement, but the South Jakarta District Court has determined that the defendant must pay costs, penalties and interest.
LAW ENFORCEMENT AGAINST HUMAN TRAFFICKING IN THE POLICE JURISDICTION AT SANGIHE ISLANDS RESORT
Authors: Anriz Revianto , Prawesthi Wahyu , Amiq Bahrul
Published: June 2024

The form of application is based on mistakes that are in accordance with legal elements and there is no reason for unlawful elimination, the element of intent by the perpetrator (dolus) so that there is no justification or reason for him/her to avoid punishment. Law enforcement efforts in the eradication of human trafficking are implemented through non-penal and penal approaches. Non-penal approaches are conducted through counseling, social education in order to develop the social responsibility of citizens who are aware of human trafficking crimes, legal counseling, resocialization, workshops, etc., especially in crime-prone environments. The penal approach is carried out through legal efforts so that perpetrators of human trafficking crimes are legally processed based on the provisions of laws and regulations up to the court level and execution in order to obtain criminal sanctions and guarantee legal certainty in society. The objective of this research is to analyze the application of criminal sanctions and law enforcement against human traffickers in the Police jurisdiction, North Sulawesi Regional District, Sangihe Islands Resort. This research used a case approach which aims to examine the application of legal norms or rules in legal practice. In addition, legislation is conducted by reviewing all laws and regulations that are related to the legal issues being addressed. The 1945 Constitution of the Republic Indonesia in one of its articles, Article 3, mentions the right not to be enslaved. Therefore, to realize the protection of this right, the Indonesian government needs to regulate human trafficking crimes separately.
ANALYSIS OF THE ROLES OF REGIONAL GOVERNMENT OF SAMPANG REGENCY IN CONTROLLING SANDSTONE MINING ACTIVITIES
Authors: Sushanty Vera Rimbawani , Putra Jejein Indramayu
Published: June 2024

The objectives of this research are to find out, analyze, and identify the consequences of sandstone mining in Gunung Rancak Village, Robatali District on environmental damage that is crowded with visitors analyzed based on Law No. 32/2009; and to find out the role of local governments in illegal sandstone mining and negative impacts on society and obligations to create a final project paper of research on the implementation of Law No. 32/2009 regulations on sandstone mining in Gunung Rancak Village. This type of research is empirical juridical. This type is an approach that aims to find out social symptoms and problems related to existing regulations in Indonesia. Researchers used interview techniques with various parties including the Head of Sampang Regency Environmental Service, the Head of Gunung Rancak Village and the people of Gunung Rancak Village regarding sandstone mining activities in Gunung Rancak Village. The result of this research is that mining activities in Gunung Rancak Village, Robatali District cause various environmental damages, both in the abiotic and biotic categories. The impact of illegal sandstone mining activities on the community and local government has a negative impact and various provisions contained in Law No. 32/2009.
THE EFFECTIVENESS OF REGIONAL GOVERNMENT EMPOWERMENT ON PHARMACEUTICAL WHOLESALER LICENSES ON THE BALI PROVINCE
Authors: Joniada I Made Wisnu , Styawati Ni Komang Arini , Arjaya I Made
Published: June 2024

Pharmaceutical wholesalers (PBF) that are already licensed by Indonesian government have complied with the pre-operational business standard requirements and during operations are required to comply with the standards of good drug distribution procedures. However, there have been some cases of PBFs that have been licensed infringing on their business licensing obligations. These infringements will affect the quality of drugs and/or drug substances which could endanger consumers. Based on this phenomenon, monitoring by regional governments is important in maintaining businesses’ compliance with business standards. The objectives of this research were to examine and analyze several factors affecting the effectiveness of regional government supervision of PBF licenses in Bali Province. The method used is empirical legal method. To address the issues within this research, the author utilizes a sociological approach, a legal regulation approach, and a conceptual approach.  Furthermore, this research indicated that Bali Provincial Health Office supervision is ineffective in assuring compliance in the fulfilling of requirements and obligations by businesses. These conditions have been affected through legal substantial factors, legal structure, and legal culture.
RESOLUTION OF NON-PERFORMING LOANS IN CREDIT AGREEMENTS WITHOUT MORTGAGE DEED AT THE CUSTOMARY VILLAGE CREDIT INSTITUTION (LPD) OF PADONAN TIBUBENENG, NORTH KUTA, BADUNG
Authors: Dewi Ni Kadek Marantina , Mahendrawati Ni Luh Made , Sukandia I Nyoman
Published: June 2024

The enactment of Law No. 4/1996 on Mortgage Rights mandates that any action establishing land rights under Law No. 5/1960 on Agrarian Principles must involve the granting of mortgage rights via APHT as debt repayment security, with the Mortgage Rights Deed being a crucial part of the debt agreement. Despite this, some financial institutions like LPD Padonan Tibubeneng Customary Village extend credit without APHT. Researchers are interested in LPD Padonan’s response to defaulted agreements, which pose a legal discrepancy. Similar cases arise in various LPDs in Bali, where credit is granted with collateral but lacks a mortgage deed, leading to legal issues upon default. LPD Padonan faces the same challenge, hindering collateral execution upon default. Empirical legal research, using legal concepts and theories, is conducted, supplemented by data from LPD Padonan. Steps taken upon default, before non-performing loan status, involve warning letters and subpoenas. If unsuccessful, credit settlement by Padonan LPD occurs through two channels: non-litigation avenues such as deliberations and credit restructuring, particularly for Padonan residents, and customary settlement through paruman.
THE IMPERATIVE OF STATE FINANCIAL RESTITUTION IN ANTI-CORRUPTION ERADICATION MEASURES
Authors: Putra Muhamad Gempa Awaljon , Usman Dr. Usman , Satoto Prof. Dr. Sukamto
Published: June 2024

Corruption is defined as a white-collar crime that mostly affects public authorities. In addition, corruption is categorized as an outstanding crime because it obstructs the people’s economy and national development. Uncontrollable corrupt practices will have a comprehensive impact on a country’s government system and can serve to further disrupt future governance. Therefore, the restoration and return of state financial losses from corruption is a high priority in upholding legislation and penal law in Indonesia. The objective of this research is examine several corruption crimes in Indonesia, their eradication efforts, and state governments’ attempts in restitution of state financial losses caused by corruption offenses. A normative juridical research method was used in this research, combined with legislative approach, case approach, comparison approach, and theoretical approach.  The research concluded that corruption offenses are divided into seven categories of offenses that can lead to losses of state finances. The eradication of on Indonesia's corruption has been realized since the New Order until now.
ENVIRONMENTAL LAW ENFORCEMENT REGULATIONS REGARDING PRODUCER OBLIGATIONS IN WASTE MANAGEMENT IN INDONESIA
Authors: Hardi Kresensia Angelica , Senastri Dr. Ni Made Jaya , Wiryani Dr. Made
Published: June 2024

Waste management in Indonesia is still an unresolved matter that deserves to be studied. This research aims to analyze the sanctions arrangements and its legal implications for producer responsibilities in managing waste in Indonesia. This research constitutes normative research which combined with primary and secondary legal sources which are then analyzed qualitatively. There are several regulations that have a correlation with this research, which are The Waste Management Law of 18/2008, along with Government Regulation 81/2012 concerning the Handling of Household Waste and Similar Waste, Presidential Regulation 97/2017 regarding the National Policy and Strategy for Managing Household and Similar Waste, and Minister of Environment and Forestry Regulation 75/2019 outlining the Roadmap for Producers to Reduce Waste, are significant legislative measures in waste management. The findings of this research indicated that the waste management obligations by producers in Indonesia have been regulated in laws and regulations, but have not been provided with sanction arrangements, which have had legal uncertainty implications on environmental law enforcement related to the legal basis for applying sanctions and legal uncertainty about the jurisdiction of both the central and regional administrations in law enforcement against producer obligations in managing waste in Indonesia.