bluuebunny/crossref_metadata_2025 huggingface dataset:
La Ley Federal de Telecomunicaciones y Radiodifusión de 2014 en México
Authors: Torres Figueroa Oneibys
Published: November 2021

El presente artículo destaca la importancia de que una legislación defina y respalde a la televisión pública en México. Se analizan los alcances y limitaciones que, en este sentido, ha tenido la Ley Federal de Telecomunicaciones y Radiodifusión de 2014. Esto se hace porque dicha legislación constituye un sistema de reglas constitutivas, que define las características y el deber ser de la televisión pública en México. También porque esta ley se refiere a los poderes deónticos que significan las relaciones de la televisión pública en el contexto político y social mexicano. Es pertinente el tema en un contexto actual de debate sobre la construcción de la noción de servicio público para los medios de comunicación en México. Existen referencias importantes de “lo público” en la Filosofía Política y en el Derecho, pero son escasas las reflexiones, al respecto, desde la Comunicación. El problema es que a la Comunicación le corresponde el análisis de los principios que rigen la manera de transformar las manifestaciones y experiencias en aspectos comunicables. Esto tiene que ver con la tarea de los medios de “publicitar” en la esfera pública y pone de manifiesto el papel de la comunicación en la realidad social. El propósito de la revisión que se hace es contribuir a la reflexión sobre la institucionalidad de la televisión pública desde el punto de vista comunicativo.
La nación de Televisa
Authors: Vidal Bonifaz Francisco J.
Published: November 2021

Este trabajo está inscrito en la tradición académica que busca demostrar que el monopolio es un proceso natural que forma parte de la dinámica histórica del capital –determinado por la llamada ley de la acumulación— y que por tanto es un proceso irreversible y que se acentúa en la medida en que opera, a lo largo del tiempo, esta ley. La historia de Televisa es representativa de este proceso y se analiza a lo largo de la historia del despliegue de sus estaciones de televisión en los diversos estados de México.
Un estudio de caso : El Correo Español como medio de información de la colonia asturiana en México (1889-1900)
Authors: Fernández Fernández Iñigo
Published: November 2021

El Porfiriato fue una época en la que aumentó la migración de los españoles y, dentro de ella, los asturianos se constituyeron en el grupo mayoritario. En este contexto, El Correo Español, hizo las veces de órgano de información oficial de la colonia hispana asentada en México a finales del siglo XIX e inicios del XX, si bien en el caso particular de los originarios del Principado, no sólo fue un mero medio de comunicación, también ayudó a construir una visión común de su región en ambas orillas del Atlántico. Para tal fin, la publicación contó con una agenda en la que las noticias que privilegió ver saban sobre el ferrocarril, la minería y los puertos, tres ejes económicos que estaba teniendo pujanza tanto en la comarca europea, al igual que en México, y que además de formar parte de un proceso de modernización, también cumplían con un anhelo ilustrado que acabar con el aislamiento que había caracterizado a Asturias gracias a su peculiar geografía.
Los riesgos del periodismo en México. El caso del documental Red Privada
Authors: Camacho Gómez María del Carmen , Casillas Camacho Diego Fernando
Published: November 2021

A lo largo de la historia del periodismo ha quedado de manifiesto que existe una relación compleja entre la prensa y grupos de poder. De forma recurrente, muchos periodistas han sido víctimas de la violencia por ejercer su profesión. En este trabajo se busca identificar las principales causas por las que los periodistas son amenazados y asesinados, al tiempo que se analiza el seguimiento de los casos, partiendo de la información presentada en el documental dirigido por Manuel Alcalá llamado Red Privada: ¿Quién mató a Manuel Buendía?
TÜRKİYE’DE YAŞLILARA YÖNELİK HİZMETLERİN YERİNDE YAŞLANMA YAKLAŞIMIYLA DEĞERLENDİRİLMESİ
Authors: BİLGİN Ömer Faruk , TAMKOÇ Betül , AYDOĞDU Özge
Published: November 2021

Doğum oranlarının azalması ve doğuşta beklenen yaşam süresinin uzaması ile dünya nüfusu hızla yaşlanmaktadır. Bu durum toplumları ekonomik, sosyal ve kültürel birçok açıdan etkilemektedir. Yaşlı nüfusa yönelik hizmet ve politikaların geliştirilmemesi durumunda gelecek yıllarda birçok ülkenin artan yaşlı nüfus için bakım ve sosyal koruma sistemleri, emekli aylıkları, sağlık sistemleri vb. konularda sorunlar ile baş etmek durumunda kalacağı öngörülmektedir. Türkiye de hızla yaşlanmakta ve yaşlı oranı giderek artmaktadır. Bu durum politika yapıcıların maliyetleri azaltacak aynı zamanda aktif, sağlıklı ve yerinde yaşlanmayı sağlayacak sosyal politikalar geliştirmesini gerektirmektedir. Bu çalışmada Türkiye’de yaşlılara yönelik hizmetlerin yerinde yaşlanma yaklaşımıyla değerlendirilmesi amaçlanmaktadır. Bu kapsamda öncelikle yerinde yaşlanma kavramı açıklanmış daha sonra Türkiye’de yaşlılara sunulan hizmetlere ilişkin bilgiler verilmiş ve yerinde yaşlanmayı sağlamaya yönelik çıkarımlarda bulunulmuştur.
Evaluation of sewer network resilience index under the perspective of ground collapse prevention
Authors: Zhang Chuanli , Oh Jeill , Park Kyoohong
Published: November 2021

Generally, when evaluating the resilience of infrastructure, the four properties of resilience (robustness, rapidity, resources, and redundancy, 4Rs) are widely considered. However, there is little research on the resilience assessment of sewer networks. Therefore, to establish a framework to evaluate sewer network resilience under the perspective of urban ground collapse prevention, this study considers the 13 second-level detailed indicators corresponding to the four first-level indicators (4Rs) based on literature reviews and experts' opinions. An analytic hierarchy process (AHP) is used to obtain relative weights of each indicator and a weighted sum method (WSM) is used to evaluate the sewer network resilience index (SRI). The evaluation system is applied to eight small blocks of selected drainage areas in Seoul, South Korea, and the SRI of eight small blocks are computed. This study could help the sewer management department to make decisions and manage sewer network assets that enhance the resilience of the sewer networks.
Bioaccessibility of Anthocyanins on in vitro Digestion Models: Factors Implicated and Role in Functional Foods Development
Authors: Prado Gabriel , Pierattini Isidora , Villarroel Guiselle , Fuentes Fernanda , Silva Alejandra , Echeverria Francisca , Valenzuela Rodrigo , Bustamante Andres
Published: November 2021

Background:

Worldwide, the prevalence of obesity and related non-communicable chronic diseases is high and continues to grow. In that sense, anthocyanins (ANC) have shown beneficial health effects in preventing obesity and metabolic risk factors. Moreover, the demand for functional foods incorporating these compounds has risen significantly in the past years. Thus, there is a need for validations of the functional properties of these formulations; nevertheless, in vivo assays are complex and require a lot of resources. One approach for estimating bioactive compounds' functionality and health benefits is to evaluate their bioaccessibility on a specific food matrix, determined by various factors. This article aims to review different factors influencing the bioaccessibility of ANC evaluated on in vitro digestion models as a functionality parameter, elucidating the effect of chemical composition, raw materials, food matrices, and vehicles for the delivery of ANC.

Methods:

Study searches were performed using PubMed, Web of Science, Scopus, and Science Direct databases.

Results:

Different factors influenced bioaccessibility and stability of ANC studied by in vitro digestion: i) the raw material used for ANC obtention; ii) food processing; iii) other food components; iv) the extraction method and solvents used; v) the structure of ANC; vi) delivery system (e.g., microencapsulation); vii) pH of the medium; viii) the digestion stage.

Conclusion:

Simulated digestion systems allow to determine free or encapsulated ANC bioaccessibility in different food matrices, which offers advantages in determining the potential functionality of a food product.
In vivo Acute Anti-Inflammatory Activity of Essential Oils: A Review
Authors: Lucca Letícia Groli , Romão Pedro Roosevelt Torres , Vignoli-Silva Márcia , da Veiga-Junior Valdir F. , Koester Letícia S.
Published: November 2021

:

In recent years, there has been a significant increase in the search for new therapeutic strategies
for the treatment of inflammatory diseases. In this sense, natural products emerge as a potential
source for the discovery of new drugs, with the research of the pharmacological properties of these
products being very important. In addition to its function in plants (insect attraction and repellency),
essential oils present pharmacological effects, such as antibacterial, antifungal, antimutagenic, antiviral,
antiprotozoal, antioxidant, antidiabetic and anti-inflammatory properties. In this review, we describe
the mostly used in vivo acute inflammatory experimental models and the studies showing the in
vivo anti-inflammatory activity of essential oils. Essential oil from species from the Apiaceae, Asteraceae,
Burseraceae, Boraginaceae, Cupressaceae, Euphorbiaceae, Fabaceae, Lamiaceae, Lauraceae,
Myrtaceae, Piperaceae, Poaceae, Rutaceae, Verbenaceae and Zingiberaceae families were described as
being anti-inflammatory in vivo. Five models of acute inflammation are commonly used to investigate
the anti-inflammatory activity in vivo: ear and paw edema, pleurisy, peritonitis and the subcutaneous
air pouch model. In addition to in vivo analysis, ex vivo and in vitro experiments are carried out to
study the anti-inflammatory action of essential oils. The most commonly used model was paw edema,
especially due to this model being easy to perform. In order to suggest or elucidate the mechanisms
involved in the anti-inflammatory effect, many studies measured some inflammatory mediators, such
as cytokines, COX-2 expression and the levels of PGE2, and NO, or evaluated the effect of essential
oils or their major compounds on inflammation response directly induced by inflammatory mediators
Minimal Residual Disease in Multiple Myeloma: an Important Tool in
Clinical Trials
Authors: Gozzetti Alessandro , Bocchia Monica
Published: November 2021

:

Minimal residual disease (MRD) detection represents a great advancement in multiple myeloma. New drugs are now available that increase depth of response. The International Myeloma Working Group recommends the use of next-generation flow cytometry (NGF) or next-generation sequencing (NGS) to search for MRD in clinical trials. Best sensitivity thresholds have to be confirmed, as well as timing to detect it. MRD has proven as the best prognosticator in many trials and promises to enter also in clinical practice to guide future therapy.
International Aid for Agricultural Development of Timor-Leste
Authors: Lee Hyejin
Published: November 2021

Background:

The Democratic Republic of Timor-Leste is the newest nation in the 21st century, which became independent in 2002. Yet continued violent tensions kept the country from stabilizing its sociopolitical situations and it remains as a least developed country with many challenging issues, including food/nutrition insecurity. The international community has been supporting Timor-Leste to ameliorate it by aiding the agricultural development of the country.

Objective:

The objective of this study is to examine the aid profile of the donors for Timorese agricultural development. The findings of the study intend to provide the Timorese government and donors with a useful dialogue point for more efficient collaboration.

Methods:

The aid data reported to the Creditor Reporting System are sorted for the profile examination. The analysis is based on the aid disbursement between 2002 and 2019.

Results:

Australia was the largest donor, mostly shaping the agricultural aid profile of the donors. Japan, USA, and New Zealand were the major donors in that order, following Australia. Yet, their prioritized sub-sectors or interests appeared to vary; Australia prioritized strengthening Timorese seed systems and focused on nutrition-sensitive agriculture, Japan emphasized rice production, USA was mainly interested in cash/horticultural crops value chains, and New Zealand invested mainly in agricultural cooperatives. Of the multilateral organizations, the European Union was the principal donor.

Conclusion:

The Timorese government and donors may need a strategic collaboration to utilize available resources more efficiently as its food/nutrition insecurity is rooted in complex issues and improving it also hinges on development of other sectors.
Linguists study language structure
Authors: Thoms Steven L. , Bonviglio Tom , Suryasa Wayan
Published: November 2021

To study linguistics is to gain a greater understanding of a fundamental part of what it means to be human. Linguistics is a scientific field and an academic discipline that has both theoretical and practical applications. Linguists study language structure at several theoretical levels that range in size from tiny units of speech sounds to the context of an entire conversation. Students of linguistics often begin with a basic understanding of each level of language, then specialize in one or more levels or in a practical application of linguistics. The smallest units of language are studied in the field of phonetics, which concerns itself with the individual sounds produced while speaking. Phonology takes a look at those small units of sound together in the context of whole utterances, and searches for patterns in sound across a language or a whole group of languages.
Implementation of interactive methodology in medical education
Authors: Mahrlamova Kamilla , Chabanovych Nadiia
Published: November 2021

Nowadays, the acquisition of innovative approaches and techniques that use the Internet is one of the main goals for the development of higher medical education in Ukraine. Blending learning is an effective way to gain knowledge in medicine and such kind of education is carried out through educational programs and curriculum and was approved for each department by the scientific council of the university. This paper describes the effectiveness of blending learning in the preparation of medical students in Ukraine. The authors designed a course “Medical English for Specific Purpose” and implemented it into the educational process. From this research, it can be concluded that blending learning is an integral part of modern education with the ability to use collaborative and critical thinking skills. In such kind of education, the role of a teacher changes to the facilitator who involves and stimulates students to go through real problem solving and meaningful lifelong learning experiences.
Georgian men’s dress of XVII century
Authors: Ugrekhelidze Irina
Published: November 2021

The article raises the issue of the importance of the work of Cristoforo de Castelli, an Italian missionary, Patrice of the Order of Theatine, in the study of Georgian historical costume. The sketches made by the author during his work in Georgia are analyzed, according to which it is possible to identify the types of clothes. According to the drawings, the clothes of different strata of the population are compared with the clothes of historical figures depicted in the monumental paintings of Georgian monuments of the same period and the clothes of the characters depicted in the illustrations of literary works. It emphasizes the identity of the costume depicted in Castelli's paintings and the miniatures of Georgian artist Mamuka Tavakarashvili and the similarity of some of the paintings. Finally, it is concluded that the visual material created over the years by Castelli as an eyewitness is still relevant today.
Genological stratification of diplomatic discourse on Twitter
Authors: Ponomarenko Olga , Smushchynska Iryna , Popivniak Olena , Tyshchenko Olena , Kovalchuk Valentyna
Published: November 2021

Scientific and technological progress with all its achievements has affected various spheres of human life. Philological disciplines, including communicative linguistics, are no exception. The means of communication have changed significantly in recent decades. No one is surprised by computer-mediated interactions, the internet has become available, and it is not difficult for many people to use personal electronic gadgets. These new developments have affected both the sphere of personal communication, including business, work, and professional relationships. All this is also relevant for diplomatic discourse, the evolutionary leap of which has taken place literally in half a century: from isolation and going beyond political discourse to the level of independent development to its current functioning with the active use of the entire palette of communication tools, methods, and techniques, including Internet resources, in particular, microblogs. The purpose of this article is to determine, describe and make an attempt to predict the levels and structure of genres of diplomatic discourse in the coming decades using examples of its manifestations on Twitter in the best traditions of classical linguistics schools and considering the achievements of new research areas in linguistics.
Criminological analysis of determinants of criminal behavior
Authors: Zabarniy Maksym , Topchii Vasyl , Korniakova Tatiana , Topchii Oksana , Topchii Vitalii
Published: November 2021

This article analyzes the process of determination of criminal conduct. The authors argue that the reasons for criminal conduct are individual and can vary significantly on a case-by-case basis. Its dependence on both biological and social factors is stated. The combination of pathological heredity, social environment, political and economic factors can cause criminal behavior. At the same time, the psychological aspects of illegal acts are taken into account within almost all criminological theories to a greater or lesser extent. Criminal behavior is always demonstrated only by an individual and, above all, it is a manifestation of psychological deformities, expressed in the phenomenon of criminogenic contamination. Therefore, understanding its essence will better determine the nature of the warning influence. As a result, it is possible to answer several questions about the determination and nature of criminal behavior, the reasons for the commission of criminal offenses, the peculiarities of the functioning of the mental sphere, psychological problems, complexes, etc. This information helps to optimize methods of crime prevention, provide for further actions of serial criminals, help in the identification of offenders and the investigation of criminal cases.
Memeology
Authors: Greene Viveca S. , Rasmussen Makena , Clark Dutch
Published: November 2021

On June 17, 2021, the Canadian Association for Security and Intelligence Studies (CASIS) Vancouver hosted a digital roundtable titled Memeology: Normalizing Hate Through Humour? The presentation was conducted by Dr. Viveca S. Greene, Associate Professor of Media Studies at Hampshire College, along with Makena Rasmussen, Writer for Meme Insider, and Dutch Clark, Intern at Trademark Event Productions. The presentation was followed by a question-and-answer period with questions from the audience and CASIS Vancouver executives.
DIAGNOSTICS AND TREATMENT OF SPASTIC HAND IN CHILDREN WITH INFANTILE CEREBRAL PARALYSIS: THE REVIEW. PART 1. THE ASSESSMENT OF UPPER EXTREMITY STATE
Authors: Umnov D. V. , Novikov V. A.
Published: November 2021

World literature disembodied data about methods of observation of upper extremity in children with infantile cerebral paralysis are elucidated and systematized in this article. The most essential research and clinical technique are described and analyzed, namely: clinical examination, the assessment of spasticity, functionality and sensibility of spastic hand, electromyography, radiography and intelligence assessment. The most often used classifications are presented.
EXPERIMENTAL STUDY OF OSTEOINTERGRATION OF SYNTHETIC MATERIAL POLYTETRAFLUOROETHYLENE IMPLANTED IN BONE
Authors: Trezubov V. N. , Galyapin I. A. , Zaytseva M. Yu.
Published: November 2021

The authors presented the results of experimental study devoted the examination of features of synthetic polymer polytetrafluoroethylene (ePTFE) implanted in the bone. It was determined that ePTFE with 70% porosity has the more marked osteointegration and can be recommended for clinical use.
THE EXPERIMENTAL MODEL OF OSTEONECROSIS
Authors: Netylko G. I. , Zaytseva M. Yu.
Published: November 2021

The experimental investigation for the purpose of modeling of knee osteonecrosis were performed in 36 rats. The chronic renal insufficiency by means of left nephrectomy and electrocoagulation in 25% cortical substance of right kidney was induced before 6 months till experiment with subsequent introduction of 0,1% adrenalin solution and methylprednisolone in paraarticular structures. The results of experiment showed the polyetiologic feature of disease.
MONOLATERAL SPINAL ANAESTHESIA IN CHILDREN
Authors: Kozyrev A. S. , Ulrikh G. E. , Zabolotsky D. V. , Kulev A. G. , Kachalova E. G. , Vissarionov S. V. , Murashko V. V.
Published: November 2021

Monolateral spinal anaesthesia as a component of general anaesthesia was compared to the spinal anaesthesia as a component of general anaesthesia for the unilateral low extremity orthopedic surgery in children. Analgesic effect of two methodics was analysed in 120 children (age 1-18 years old, ASA 1-2). Monolateral spinal anesthesia provides the same level of analgesia thus decreasing zone of desympathysation and providing more hemodynamic stability and decreasing loss of heat. Monolateral spinal anesthesia is not complicated with urinary retention in contrast to classic spinal anaesthesia. Monolateral spinal anesthesia is an effective alternative to a classical spinal anesthesia for the unilateral low extremity orthopedic surgery in children.
CAPABILITIES OF ELECTRONEUROSTIMULATION IN PATIENTS WITH VERTEBRAL-SPINAL INJURIES
Authors: Toma A. I. , Ninel V. G. , Norkin I. A. , Toma G. V. , Smol'kin A. A.
Published: November 2021

The possibilities of epidural electrical stimulation in the complex treatment of patients with spinal injury in the acute and late periods of traumatic disease of the spinal cord. The authors presented the analysis of treatment results of 356 patients with a spinal-cord injury at age 16 to 71 years, including 293 patients in the acute and early periods of trauma, and 63 - in the late period. Injuries of the cervical spine were observed in 145 (40,7%) men, thoracic - in 59 (16,6%), thoracolumbar - in 89 (25,0%), lumbar - in 63 (17,7%). As the result of the conducted electropulse influence on the spinal cord in the acute period of the trauma we succeeded in achieving positive outcomes in 80,9% of patients, and that is 11,7% better, than in the comparison group. That allowed us to restore lost functions of the spinal cord more completely in more than the half of the patients with consequences of vertebral cerebro-spinal trauma.
TACTIC OF SURGICAL TREATMENT OF PATIENTS WITH THE OLD VERTEBRAL AND SPINAL CORD INJURIES
Authors: Usikov V. D. , Fadeev E. M. , Ptashnikov D. A. , Magomedov Sh. Sh. , Dokish M. Yu.
Published: November 2021

The 329 patients with the old vertebral and spinal cord injuries have been treated surgically in 6 month - 18 years after injury. Tactics of surgical treatment of patients was based on fracture type, degree of neurological deficit and rigidity of deformation. The combination of neurosurgical and orthopedical principles of surgery lets us to achieve an improvement in live quality in 92,7% of cases.
CRIO-INFLUENCE IN SURGICAL TREATMENT OF BENIGN TUMOURS OF FOOT BONES
Authors: Dianov S. V. , Halagummaev K. M.
Published: November 2021

The material of investigation was the results of treatment of 131 patients with foot bones tumours. The largest number of patients referred, to age interval from 11 to 30 years (69,6%). More than half of cases were osteochondromas (54%), then solitary bone cyst (14,5%) and chondromas (13%). Other nosologic forms were met significantly seldom. Two groups of patients were examined: the main group (with crio-influence) - 44 patients and group of comparison (without crio-influence) - 87 patients. The plot of operation was in flat, border-line, intrafocusal or segmental resection of damaged section, crio-instillation or contact curio-processing of bone and auto- or allopathic of respected defect. The results of treatment were estimated in a year after operation. After usage of curio-surgical method there were observed positive results in 41 patients, satisfactory - in 2 and unsatisfactory - in 1. The results of treatment with traditional method were positive in 79 cases, satisfactory - in 2, unsatisfactory - in 6. The worked-out method of curio-surgical treatment of foot bone tumours includes resection of pathological focus, itraoperative crio-influence on bone tissue and bone plastic transplantation of resected, defect. The analysis of criosurgical operations of foot gave the foundation to consider such interventions significant and perspective in treatment of patients with tumours and tumour similar damages of foot bone.
Invernadero bioclimático y modular para clima cálido: Diseño, construcción, operación y mantenimiento
Authors: Villagrán Munar Edwin Andrés , Jaramillo Noreña Jorge Eliécer , Rodríguez Roa Andrea Onelia , León Pacheco Rommel Igor , Yacomelo Hernández Marlón José
Published: November 2021

Esta obra tiene por objeto mostrar las características del montaje de un invernadero bioclimático ventilado de acuerdo con un diseño desarrollado el 2019 en el departamento de Magdalena, Colombia. Este diseño está basado en un modelo computacional de fluidos (CFD) 2-D para el desarrollo de simulaciones en estado estacionario, modelo que fue validado experimentalmente en el prototipo del invernadero real evaluado. Se destacan los siguientes contenidos de esta publicación: 1) descripción de la fase de diseño computacional apoyado en herramientas de modelado y simulación numérica, en el que se detallan preproceso, proceso y posproceso, 2) diseño arquitectónico, validación de las condiciones microclimáticas dentro de la estructura y método de medición de las variables asociadas al clima, 3) proceso de construcción, 4) presupuesto y 5) criterios para el mantenimiento. El invernadero bioclimático ventilado es una alternativa para intensificar la agricultura y mejorar la seguridad alimentaria en estas regiones de clima cálido, ya que está orientado a superar de manera eficiente las limitaciones usualmente impuestas por factores bióticos y abióticos que afectan la producción agrícola de estas zonas.
A Platform and Multisided Market for Translational, Software-Defined Medical Procedures in the Operating Room (OP 4.1): Proof-of-Concept Study
Authors: Görtz Magdalena , Byczkowski Michael , Rath Mathias , Schütz Viktoria , Reimold Philipp , Gasch Claudia , Simpfendörfer Tobias , März Keno , Seitel Alexander , Nolden Marco , Ross Tobias , Mindroc-Filimon Diana , Michael Dominik , Metzger Jasmin , Onogur Sinan , Speidel Stefanie , Mündermann Lars , Fallert Johannes , Müller Michael , von Knebel Doeberitz Magnus , Teber Dogu , Seitz Peter , Maier-Hein Lena , Duensing Stefan , Hohenfellner Markus
Published: November 2021

Background

Although digital and data-based technologies are widespread in various industries in the context of Industry 4.0, the use of smart connected devices in health care is still in its infancy. Innovative solutions for the medical environment are affected by difficult access to medical device data and high barriers to market entry because of proprietary systems.

Objective

In the proof-of-concept project OP 4.1, we show the business viability of connecting and augmenting medical devices and data through software add-ons by giving companies a technical and commercial platform for the development, implementation, distribution, and billing of innovative software solutions.

Methods

The creation of a central platform prototype requires the collaboration of several independent market contenders, including medical users, software developers, medical device manufacturers, and platform providers. A dedicated consortium of clinical and scientific partners as well as industry partners was set up.

Results

We demonstrate the successful development of the prototype of a user-centric, open, and extensible platform for the intelligent support of processes starting with the operating room. By connecting heterogeneous data sources and medical devices from different manufacturers and making them accessible for software developers and medical users, the cloud-based platform OP 4.1 enables the augmentation of medical devices and procedures through software-based solutions. The platform also allows for the demand-oriented billing of apps and medical devices, thus permitting software-based solutions to fast-track their economic development and become commercially successful.

Conclusions

The technology and business platform OP 4.1 creates a multisided market for the successful development, implementation, distribution, and billing of new software solutions in the operating room and in the health care sector in general. Consequently, software-based medical innovation can be translated into clinical routine quickly, efficiently, and cost-effectively, optimizing the treatment of patients through smartly assisted procedures.
Knowledge and Expectations of Hearing Aid Apps Among Smartphone Users and Hearing Professionals: Cross-sectional Survey
Authors: Han Jae Sang , Park Yong-Ho , Song Jae-Jun , Moon Il Joon , Lee Woojoo , Kim Yoonjoong , Cho Young Sang , Seo Jae-Hyun , Park Moo Kyun
Published: November 2021

Background

Despite the increasing prevalence of hearing loss, the cost and psychological barriers to the use of hearing aids may prevent their use in individuals with hearing loss. Patients with hearing loss can benefit from smartphone-based hearing aid apps (SHAAs), which are smartphone apps that use a mobile device as a sound amplifier.

Objective

The aim of this study is to determine how ear, nose, and throat outpatients perceive SHAAs, analyze the factors that affect their perceptions, and estimate the costs of an annual subscription to an app through a self-administered questionnaire survey of smartphone users and hearing specialists.

Methods

This study used a cross-sectional, multicenter survey of both ear, nose, and throat outpatients and hearing specialists. The questionnaire was designed to collect personal information about the respondents and their responses to 18 questions concerning SHAAs in five domains: knowledge, needs, cost, expectations, and information. Perception questions were rated on a scale of 1 (strongly disagree) to 5 (strongly agree). Questions about the expected cost of SHAAs were included in the questionnaire distributed to hearing experts.

Results

Among the 219 smartphone users and 42 hearing specialists, only 8 (3.7%) respondents recognized SHAAs, whereas 18% (47/261) of respondents reported considering the use of an assistive device to improve their hearing capacity. The average perception score was 2.81 (SD 1.22). Among the factors that shaped perceptions of SHAAs, the needs category received the lowest scores (2.02, SD 1.42), whereas the cost category received the highest scores (3.29, SD 1.14). Age was correlated with the information domain (P<.001), and an increased level of hearing impairment resulted in significantly higher points in the needs category (P<.001). Patients expected the cost of an annual app subscription to an SHAA to be approximately US $86, and the predicted cost was associated with economic status (P=.02) and was higher than the prices expected by hearing specialists (P<.001).

Conclusions

Outpatients expected SHAAs to cost more than hearing specialists. However, the perception of the SHAA was relatively low. In this regard, enhanced awareness is required to popularize SHAAs.
Reduction of Platelet Outdating and Shortage by Forecasting Demand With Statistical Learning and Deep Neural Networks: Modeling Study
Authors: Schilling Maximilian , Rickmann Lennart , Hutschenreuter Gabriele , Spreckelsen Cord
Published: November 2021

Background

Platelets are a valuable and perishable blood product. Managing platelet inventory is a demanding task because of short shelf lives and high variation in daily platelet use patterns. Predicting platelet demand is a promising step toward avoiding obsolescence and shortages and ensuring optimal care.

Objective

The aim of this study is to forecast platelet demand for a given hospital using both a statistical model and a deep neural network. In addition, we aim to calculate the possible reduction in waste and shortage of platelets using said predictions in a retrospective simulation of the platelet inventory.

Methods

Predictions of daily platelet demand were made by a least absolute shrinkage and selection operator (LASSO) model and a recurrent neural network (RNN) with long short-term memory (LSTM). Both models used the same set of 81 clinical features. Predictions were passed to a simulation of the blood inventory to calculate the possible reduction in waste and shortage as compared with historical data.

Results

From January 1, 2008, to December 31, 2018, the waste and shortage rates for platelets were 10.1% and 6.5%, respectively. In simulations of platelet inventory, waste could be lowered to 4.9% with the LASSO and 5% with the RNN, whereas shortages were 2.1% and 1.7% with the LASSO and RNN, respectively. Daily predictions of platelet demand for the next 2 days had mean absolute percent errors of 25.5% (95% CI 24.6%-26.6%) with the LASSO and 26.3% (95% CI 25.3%-27.4%) with the LSTM (P=.01). Predictions for the next 4 days had mean absolute percent errors of 18.1% (95% CI 17.6%-18.6%) with the LASSO and 19.2% (95% CI 18.6%-19.8%) with the LSTM (P<.001).

Conclusions

Both models allow for predictions of platelet demand with similar and sufficient accuracy to significantly reduce waste and shortage in a retrospective simulation study. The possible improvements in platelet inventory management are roughly equivalent to US $250,000 per year.
The Effects of Virtual Reality Treatment on Prefrontal Cortex Activity in Patients With Social Anxiety Disorder: Participatory and Interactive Virtual Reality Treatment Study
Authors: Lee Hojun , Choi JongKwan , Jung Dooyoung , Hur Ji-Won , Cho Chul-Hyun
Published: November 2021

Background

Attempts to use virtual reality (VR) as a treatment for various psychiatric disorders have been made recently, and many researchers have identified the effects of VR in psychiatric disorders. Studies have reported that VR therapy is effective in social anxiety disorder (SAD). However, there is no prior study on the neural correlates of VR therapy in patients with SAD.

Objective

The aim of this study is to find the neural correlates of VR therapy by evaluating the treatment effectiveness of VR in patients with SAD using portable functional near-infrared spectroscopy (fNIRS).

Methods

Patients with SAD (n=28) were provided with 6 sessions of VR treatment that was developed for exposure to social situations with a recording system of each participant’s self-introduction in VR. After each VR treatment session, the first-person view (video 1) and third-person view (video 2) clips of the participant’s self-introduction were automatically generated. The functional activities of prefrontal regions were measured by fNIRS while watching videos 1 and 2 with a cognitive task, before and after whole VR treatment sessions, and after the first session of VR treatment. We compared the data of fNIRS between patients with SAD and healthy controls (HCs; n=27).

Results

We found that reduction in activities of the right frontopolar prefrontal cortex (FPPFC) in HCs was greater than in the SAD group at baseline (t=–2.01, P=.049). Comparing the frontal cortex activation before and after VR treatment sessions in the SAD group showed significant differences in activities of the FPPFC (right: t=–2.93, P<.001; left: t=–2.25, P=.03) and the orbitofrontal cortex (OFC) (right: t=–2.10, P=.045; left: t=–2.21, P=.04) while watching video 2.

Conclusions

Activities of the FPPFC and OFC were associated with symptom reduction after VR treatment for SAD. Our study findings might provide a clue to understanding the mechanisms underlying VR treatment for SAD.

Trial Registration

Clinical Research Information Service (CRIS) KCT0003854; https://tinyurl.com/559jp2kp
Smartphone Ownership and Interest in Mobile Health Technologies for Self-care Among Patients With Chronic Heart Failure: Cross-sectional Survey Study
Authors: Leigh Jonathan W , Gerber Ben S , Gans Christopher P , Kansal Mayank M , Kitsiou Spyros
Published: November 2021

Background

Heart failure (HF) is a highly prevalent chronic condition that places a substantial burden on patients, families, and health care systems worldwide. Recent advances in mobile health (mHealth) technologies offer great opportunities for supporting many aspects of HF self-care. There is a need to better understand patients’ adoption of and interest in using mHealth for self-monitoring and management of HF symptoms.

Objective

The purpose of this study is to assess smartphone ownership and patient attitudes toward using mHealth technologies for HF self-care in a predominantly minority population in an urban clinical setting.

Methods

We conducted a cross-sectional survey of adult outpatients (aged ≥18 years) at an academic outpatient HF clinic in the Midwest. The survey comprised 34 questions assessing patient demographics, ownership of smartphones and other mHealth devices, frequently used smartphone features, use of mHealth apps, and interest in using mHealth technologies for vital sign and HF symptom self-monitoring and management.

Results

A total of 144 patients were approached, of which 100 (69.4%) participated in the study (63/100, 63% women). The participants had a mean age of 61.3 (SD 12.25) years and were predominantly Black or African American (61/100, 61%) and Hispanic or Latino (18/100, 18%). Almost all participants (93/100, 93%) owned a cell phone. The share of patients who owned a smartphone was 68% (68/100). Racial and ethnic minorities that identified as Black or African American or Hispanic or Latino reported higher smartphone ownership rates compared with White patients with HF (45/61, 74% Black or African American and 11/18, 61% Hispanic or Latino vs 9/17, 53% White). There was a moderate and statistically significant association between smartphone ownership and age (Cramér V [ΦC]=0.35; P<.001), education (ΦC=0.29; P=.001), and employment status (ΦC=0.3; P=.01). The most common smartphone features used by the participants were SMS text messaging (51/68, 75%), internet browsing (43/68, 63%), and mobile apps (41/68, 60%). The use of mHealth apps and wearable activity trackers (eg, Fitbits) for self-monitoring of HF-related parameters was low (15/68, 22% and 15/100, 15%, respectively). The most popular HF-related self-care measures participants would like to monitor using mHealth technologies were physical activity (46/68, 68%), blood pressure (44/68, 65%), and medication use (40/68, 59%).

Conclusions

Most patients with HF have smartphones and are interested in using commercial mHealth apps and connected health devices to self-monitor their condition. Thus, there is a great opportunity to capitalize on the high smartphone ownership among racial and ethnic minority patients to increase reach and enhance HF self-management through mHealth interventions.
Self-compassion Education for Health Professionals (Nurses and Midwives): Protocol for a Sequential Explanatory Mixed Methods Study (Preprint)
Authors: Steen Mary , Othman Shwikar Mahmoud Etman , Briley Annette , Vernon Rachael , Hutchinson Steven , Dyer Susan
Published: November 2021

BACKGROUND

A few recent studies have reported that having the ability to provide self-compassion can reduce health professionals’ levels of anxiety and stress, the risk of compassion fatigue, and burnout, and it can generally improve their well-being. Therefore, there is evidence to support further research into the investigation and exploration of self-compassion education and training for health professionals.

OBJECTIVE

This study aims to increase the knowledge and understanding of self-compassion and how this may enhance the health and well-being of health professionals.

METHODS

The proposed research study will adopt a sequential explanatory mixed methods design. This study will be conducted in 3 phases. Phase 1 will use a pre-educational self-compassion questionnaire (web-based survey) to collect data from participants at 3 time points (before, immediately after, and after follow-up at 6-8 weeks) after they have attended a self-compassion education and training program. Phase 2 will use an interview schedule to explore the participants’ views and experiences through a follow-up focus group or individual interview. Finally, phase 3 will include data integration and dissemination of key findings and recommendations.

RESULTS

This study was approved by the Women’s and Children’s Health Network Human Research Ethics Committee and the Human Research Ethics Committee at the University of South Australia on June 26, 2021 (ID: 204,074). A scoping review was conducted to inform this research study (focusing on nurses and midwives). The preparatory phase was completed in April 2021. Phase 1 is expected to be completed by June 2022 and phase 2 will commence in July 2022.

CONCLUSIONS

The key findings from the data integration for this research project will provide in-depth details and insights to broaden the discussion about self-compassion and its influence on health professionals’ health and well-being. Health professionals (nurses and midwives) may benefit from self-compassion education and training programs to improve their health and well-being.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/34372
Ernst Moro: returning the names
Authors: Pashchenko I.V. , Ivanko O.G.
Published: November 2021

The purpose of the publication is an invitation to honor the outstanding pediatrician Ernst Moro (1874–1951), with an attempt to return his pronunciation of the surname by emphasizing the first syllable (Móro), to recall the life and creative career of this outstanding scientist and doctor. The Moro reflex described in 1918 is now widely used by modern pediatricians and pediatric neurologists in everyday practice. Ernst Moro’s scientific achievements in the development of a skin test for tuberculosis diagnostics, the organization of the efforts against diarrhea in young children, and the formation of pediatric dietology have made Ernst Moro’s scientific heritage extremely important for modern pediatrics.
PENGARUH KEPUASAN WISATAWAN TERHADAP WILLINGNESS TO PAY TAMAN WISATA ALAM KAWAH IJEN
Authors: Cardias Esa Riandy
Published: November 2021

Taman Wisata Alam Kawah Ijen (92 ha) merupakan bagian dari kawasan Cagar Alam Kawah Ijen (2.468 ha) tempat berbagai biota langka dilindungi. UNESCO menetapkan Kawah Ijen sebagai salah satu Cagar Biosfer  dari 120 negara di dunia (2016). Segala keunikan yang dimiliki TWAKI menyebabkan kunjungan wisatawan ke  destinasi ini cenderung meningkat signifikan, dan pada akhirnya daya dukung lingkungan terlampaui empat tahun terakhir. Oleh karenanya dibutuhkan pengelolaan destinasi yang tepat, namun dibutuhkan dana yang tidak sedikit. Willingness to pay (WTP) wisatawan diharapkan sebagai sumber pendanaan lain diluar pemerintah, dan patokan dalam mengukur WTP adalah memberikan kepuasan maksimal kepada wisatawan. Penelitian ini bertujuan menganalisis tingkat kepuasan wisatawan dan pengaruhnya terhadap WTP, serta tingkatan WTP. Penelitian ini dirancang menggunakan metode kuantitatif  dengan alat Partial Least Square Path Modelling (PLS-PM). Metode tersebut dipilih untuk mengetahui ukuran korelasional dan kausal antar variabel serta menguji signifikansi dari hipotesis. Hasil penelitian menunjukan aspek atraksi, amenitas, aksesibilitas eksternal, aksesibilitas internal, sumber daya manusia, dan citra destinasi merefleksikan  kepuasan wisatawan; kepuasan wisatawan berdasarkan aspek atraksi wisata, sumber daya manusia, dan citra destinasi berpengaruh positif dan signifikan terhadap WTP. Sementara kepuasan wisatawan berdasarkan aspek amenitas; aksesibilitas eksternal; dan aksesibilitas internal tidak berpengaruh terhadap WTP. Nilai rataan WTP wisatawan mancanegara US$ 28 dan Rp.25.000  wisatawan nusantara, sehingga masing-masing nilai ekonomi ekowisata dan perkiraan pendapatan dari penjualan tiket berdasarkan nilai WTP adalah US$ 864.528 atau sekitar 12 milyar dan Rp.3.776.800.000.
Penerapan Sistem Menu Engineering Dalam Upaya Peningkatan Kualitas Menu di Restoran Bintan Inti Executive Village Clubhouse
Authors: Tumpuan Adiguna
Published: November 2021

This research is a form of analysis and evaluation of the menu at the Bintan Inti Executive Village (BIEV) Clubhouse through a menu engineering system with the aim of improving the quality and effectiveness of the menu served. The formulation of the problem which is the basis of this research is how to improve the quality of the food and beverage menu through the menu engineering system and what recommendation actions should be taken based on the resulting data from the analysis that appears. This study uses variables, which are menu analysis in improving the quality of the menu at BIEV Clubhouse with sub variables, such as food cost, menu mix, and contribution margin. The results of this study that there were 8 menus or 30.77% menus with star categories, 5 menus or 19.23% menus with the plowhorse category, 4 menus or 15.38% menus with the puzzle category, and 9 menus or 34.62%. menu with dog category. The recommended follow-up actions to BIEV Clubhouse management is reducing the menu with the dog category, evaluating product prices and production costs for menus with the plowhorse category, taking suggestive selling steps for menus with the puzzle category, and maintaining the quality and performance of menus with the star category.
ОСОБЕННОСТИ ТЕХНОЛОГИИ ИЗГОТОВЛЕНИЯ ЧУВСТВИТЕЛЬНЫХ ЭЛЕМЕНТОВ МАЯТНИКОВОГО МИКРОАКСЕЛЕРОМЕТРА ДЛЯ ИНЕРЦИАЛЬНЫХ МОДУЛЕЙ ПЕРСПЕКТИВНЫХ СИСТЕМ ТЕХНИЧЕСКОГО КОНТРОЛЯ
Authors: Обижаев Д.Ю. , Жукова С.А. , Суздальцев С.Ю. , Сальникова Т.В. , Иванов С.Ю.
Published: November 2021

В настоящей работе представлены результаты оптимизации технологии создания чувствительных элементов микроакселерометров в целях устранения нежелательного эффекта «подлипания» маятников в процессе их изготовления и эксплуатации. Проведена оценка максимально допустимой площади диэлектрических упоров.
ТУННЕЛЬНЫЕ МАГНИТНЫЕ КОНТАКТЫ ДЛЯ СИСТЕМ ПАМЯТИ И ЧУВСТВИТЕЛЬНЫХ ДАТЧИКОВ МАГНИТНОГО ПОЛЯ
Authors: Пашенькин И.Ю. , Сапожников М.В. , Гусев Н.С. , Гусев С.А. , Татарский Д.А. , Фраерман А.А.
Published: November 2021

Разработана технология получения туннельных магнитных контактов на основе многослойных структур CoFeB / MgO / CoFeB, демонстрирующих магнетосопротивление величиной ~200 % и пригодных для использования при построении систем энергонезависимой памяти и датчиков магнитного поля. Показано, что магнитное состояние этих туннельных контактов может изменяться под действием электрического поля.
ИССЛЕДОВАНИЕ ДИОДНОЙ НАКАЧКИ ДЛЯ ГЕНЕРАТОРА НЕСУЩЕЙ В ФОТОННЫХ СХЕМАХ
Authors: Якушенков П.О. , Чешев Е.А. , Горбунков М.В. , Тупицын И.М.
Published: November 2021

В настоящее время радиофотоника является приоритетным направлением исследования. Для генерации несущей в фотонных схемах используются лазеры с синхронизацией мод. Доклад посвящен исследованию диодной накачки для лазера с синхронизацией мод и сравнению ее с волоконной накачкой.