bluuebunny/crossref_metadata_2025 huggingface dataset:
miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q
Authors: Xu Nan , Li Ang-Di , Ji Li-Li , Ye Yao , Wang Zhen-Yu , Tong Lei
Published: May 2019

Cognitive impairment in Alzheimer’s disease (AD) is usually accompanied by synaptic loss in both the hippocampus and neocortex. In the early stage of AD, amyloid β-induced synapse changes is the main reason, while in the later stage, the accumulation of Tau protein promotes synapse degeneration as the key factor leading to dementia. MicroRNA (miRNA) is closely related to the expression changes of many AD-related genes. One of the most abundant brain-enriched miRNAs is miR-132, which has been shown to regulate both neuron morphogenesis and plasticity. It has been reported that miR-132 is significantly reduced in the brains of Alzheimer’s patients. Genetic deletion of miR-132 in mice promotes Aβ deposition, leading to impaired memory and enhanced Tau pathology, but how the miRNA-mediated gene expression dysregulation contributes to AD pathology remains unclear. Here we found the possible downstream target of miR-132 by in silico analysis, namely C1q. C1q is the primary protein of classical complement cascade, which is highly expressed in the synaptic regions of the central nervous system in Alzheimer’s patients. However, it is not clear whether miR-132 plays a role in AD through regulating C1q. To address this question, the APP/PS1 transgenic mice were transfected with miR-132 and given C1 inhibitors. Behavior tests were conducted to assess memory and cognitive abilities seven days after administration. In addition, we analyzed the expression of PSD95, Synapsin-1 and phosphorylated (p)-Synapsin. We found that the expression levels of the synaptic proteins treated with miR-132 or C1INH were significantly increased compared with the AD group. Further RT-qPCR result suggested that miR-132 might regulate C1q expression in AD.
Anticancer potential of ascorbic acid and inorganic selenium on human breast cancer cell line MCF-7 and colon carcinoma HCT-116
Authors: Ganash Magdah A.
Published: May 2019

Background and Objectives:

Till now, cancer is a major health problem and one of the main causes of mortality worldwide. Ascorbic acid and selenium are the two most popular dietary supplements used to prevent cancer proliferative, therefore, the work aims to study the antitumor effect of ascorbic acid and selenium on HCT116 and MCF7 cell lines.

Materials and Methods:

In the present study, the cytotoxic effect of different concentrations of ascorbic acid and selenium on human breast cancer cell line (MCF7 cells) and human colon carcinoma (HCT116) was studied.

Results:

Viability % of HCT116 cell line and MCF7 cell line decreased with increasing ascorbic acid concentrations (1–4 mM). The 50% inhibitory concentration (IC50) of five dilutions of each concentration of ascorbic acid was evaluated in the current study. IC50 was 0.18, 0.17, 0.16, and 0.16 mM for HCT116 cell line and was 0.86, 1.34, 1.74, and 0.47 mM for MCF7 cell line at 1, 2, 3, and 4 mM, respectively. Cell viability decreased depending on the selenium concentrations ranging from 20 to 100 mM. Selenium effect showed less cytotoxicity on MCF7 compared to HCT116 cells at all tested concentrations where the cell viability at 20, 40, 60, 80, and 100 mM selenium was 33.74, 29.48, 26.08, 54.53, and 20.89 for HCT116 cell and was 79.53, 76.01, 59.42, 54.53, and 51.98 for MCF7 cell, respectively. Ascorbic acid induced apoptosis by promoting the release of lactate dehydrogenase (LDH) in HCT116 and MCF7 cells, but reduced release of LDH was observed in selenium treatment but increased when it added to ascorbic acid because of a possible synergistic action that may produce an enhanced anticarcinogenic effect.

Conclusion:

The present study documented that a combination of ascorbic acid and selenium produces an additive chemopreventive effect on carcinogenesis.
Extracellular Signal-Regulated Kinase (ERK) Inhibitors in Oncology Clinical Trials
Authors: Chin Haelee M , Lai David K , Falchook Gerald S
Published: May 2019

The mitogen-activated protein kinase (MAPK) pathway consists of the series of protein kinases RAS-RAF-MEK-Extracellular signal-regulated kinase (ERK), and its function is important to cell proliferation, differentiation, motility, and survival. Certain mutations in the pathway, such as KRAS or BRAF V600 mutations are associated with cancer. Inhibitors of this pathway, including some MEK and BRAF inhibitors, are already being used in the clinic, but a variety of selective ERK inhibitors are still being tested in clinical studies. To date, common adverse events associated with ERK inhibitors include diarrhea, nausea, fatigue, and rash. ERK inhibitors have demonstrated preliminary antitumor activity and may be most effective against cancers with RAS, RAF, or MAPK pathway alterations. This review discusses the MAPK pathway, the biological rationale for ERK inhibitors, and clinical trials involving ERK inhibitors.
The Study of Druggable Targets in Nonsquamous Non-Small-Cell Lung Cancer in the Middle East and North Africa
Authors: Jazieh Abdul Rahman , Bounedjar Adda , Al Dayel Fouad , Fahem Shamayel , Tfayli Arafat , Rasul Kakil , Jaafar Hassan , Jaloudi Mohammad , Al Fayea Turki , Al Maghrabi Hatim Q , Bamefleh Hanaa , Al Kattan Khaled , Larbaoui Blaha , Filali Taha , Al Husaini Hamed , Ali Yosra ,   in collaboration with the Arab Collaborative Hematology Oncology Group (ACHOG)
Published: May 2019

Background: Druggable molecular targets are very important in the management of non-small-cell lung cancer (NSCLC). The purpose of our study is to determine the pattern of testing and mutation prevalence in the Middle East and North Africa population. Patients and Methods: Data of consecutive patients with nonsquamous NSCLC were collected from 10 centers in five countries; Saudi Arabia, UAE, Qatar, Lebanon, and Algeria. Statistical analysis was performed to delineate the prevalence of druggable targets and other relevant information. Results: Five hundred and sixty-six patients were included in the study. Majority were males (78.1%) with a median age of 61 years (22–89), 50% were current or ex-smokers and 370 patients (65.4%) were Stage IV. The epidermal growth factor receptor (EGFR) testing was performed on 164 patients of all stages. EGFR mutation was detected in 30 out of 96 patients (31.3%) with metastatic disease and in 12 out of 68 patients (17.6%) with Stage I to III. Female sex (39.5% vs. 22% males, P = 0.032), Stage IV (31.2% vs. 17.6% in Stage I to III, P = 0.049), and positive immunohistochemical-TTF1 (31.4% vs. 8.7% negative, P = 0.026) were predictors of mutation on univariate analysis. The multivariate analysis showed that patients with stage IV have three times higher positivity than lower stages (odds ratio = 3.495, P = 0.036). Anaplastic lymphoma kinase fusion was present in seven out of 89 patients (7.8%) of all stages, and only three out of 52 patients (5.8%) with metastatic disease. The reasons for not performing the tests in all of the 370 patients with metastatic disease were: physicians do not know where and how to send the test (62.3%), lack of funding to perform the test (11.1%), insufficient tissue (10.1%), and other reasons (16.6%). Conclusions: Only a small fraction of patients with NSCLC are tested for druggable targets and the prevalence of EGFR mutation is prevalence higher than the Western population. Overcoming the challenges of testing requires systematic plans to address education and resource allocation.
Validated Identity Test Method for Ginkgo biloba NHPs Using DNA-Based Species-Specific Hydrolysis PCR Probe
Authors: Dhivya Shanmughanandhan , Ragupathy Subramanyam , Kesanakurti Prasad , Jeevitha Shanmughanandhan , Noce Isabella Della , Newmaster Steven G.
Published: May 2019

Background: There is considerable risk of adulteration of Ginkgo biloba herbal products in the natural health product (NHP) industry. Authentication of G. biloba products is challenging because of the standard, complex, analytical chemistry methods that may be too
costly and not appropriate for both raw and finished products. Objective: We sought to develop and validate an alternative method to authenticate G. biloba herbal dietary supplements, based on the use of a species-specific hydrolysis PCR probe assay. Methods: A species-specific
hydrolysis probe assay was developed, validated, and evaluated for the performance of the assay in accurately identifying the species of interest using the following analytical validation criteria: (1) specificity (accuracy) in identifying the target species ingredient, while not identifying
other nontarget species, (2) sensitivity in detecting the smallest amount of the target material, and (3) reliability (repeatability and reproducibility) in detecting the target species in raw materials on a real-time PCR platform. Results: The species-specific hydrolysis
probe assay was successfully developed for raw materials of G. biloba. The specificity of the assay was 100% to the target species. Efficiency of the assay was observed to be 99%, and the reliability of the assay was 100% for the raw/starting materials. Conclusions and Highlights:
The method developed in this study is simple, rapid, and easy for supplement manufacturers to perform in their laboratories to ensure that their G. biloba supplements are authentic.
CONCORDÂNCIA INTEROBSERVADORES DA DETECÇÃO DO FATOR CORDA PARA A IDENTIFICAÇÃO PRESUNTIVA DO MYCOBACTERIUM TUBERCULOSIS
Authors: Henrique  Marques  Franco Paulo , Yukari  Ueno Priscilla , Adélia  Fernandes Daniela , AparecidaSilva de Aguiar Amanda , Rafael Teixeira Regina , dos Santos de Barros Lordelo André , Chiari Galle Leonilda , Peresi Lordelo Eliana
Published: May 2019

Detection of cord factor may favor the definitive diagnosis and initiation of antituberculosistreatment. The aim of this study was to evaluate the interobserver concordance of mycobacterial smears stained with Ziehl-Neelsen technique for the presumptive identification of the Mycobacterium tuberculosis (M. tuberculosis).Three observers, healthcare students, conducted a blind reading of 30 slides stained with Ziehl-Neelsen and their results were compared to the results of an experient reader. Kappa coefficient with 95% interval was used to evaluate the concordance betweenthe readings. No excellent interobserver concordance(κ>0.75) was found. The interpretation and use of the cord factor for the presumptive identification of the M. tuberculosisis a technique that requires training for the interpretation of the variables of the smear stained with Ziehl-Neelsen technique and theoretical knowledge of the observer to deliver a correct result.
CORRELAÇÃO ENTRE TAXA METABÓLICA BASAL E VARIABILIDADE DA FREQUÊNCIA CARDÍACA NO TREINAMENTO RESISTIDO FUNCIONAL EM INDIVÍDUOS COM SÍNDROME METABÓLICA
Authors: Reis  Jockner Mariana , Priscilla  de  Souza  Cavina Allysiê , Custódio  Junior Altair , Kirsch  Micheletti Jéssica , Ryu Takahama Bruno , Netto Junior Jayme , Marques Vanderlei Franciele
Published: May 2019

Physical exercise is a non-pharmacological alternative to act on the indicators of the metabolic syndrome (MS). Functional resistance training (FRT), recruits a greater number of muscle groups, which can lead to greater energy expenditure. Therefore, the aim of this study was to analyze the correlation between the basal metabolic rate (BMR) and the heart rate variability (HRV) in FRT in individuals with MS. The study was a non-randomized clinical trial consisting of 32 subjects who had MS who were divided into functional resistance training group (FRTG) and control group (CG). The HRV was collected with a cardiofrequency meter and the vagal indices were selected and for the analysis of BMR was performed by bioimpedance. Correlation was observed for the HF index with BMR only prior to FRT. Therefore, there is no significant correlation between vagal indices and BMR in individuals with MS after performing RFT.
LEVANTAMENTO DE FAUNA ENTOMONECRÓFAGA DE IMPORTÂNCIA FORENSE ATRAÍDA POR ISCAS COM CARNE SUÍNA (SUS SCROFA L.)NO DISTRITO DE ROSANA-SP
Authors: Santana Motta de Campos Daniel , Paula Nunes Zago Oliveira Ana
Published: May 2019

Studies with necrophagous insects essentially helps in the determination of postmortem interval (PMI) of an organism and provides necessary information for criminal investigations in the forensic area. The necrophagous insects with greater incidence in forensic studies belongs to Calliphoridae, Sarcophagidae, Muscidae (Diptera) and Dermestidae (Coleoptera) families. The research was realized near the district of Rosana -SP, in a region known as Pontal do Paranapanema. Traps made with PET bottles with ground pork inside (Sus scrofaL.) were used in an agricultural area surrounding the local diversity. The traps were exposed for 17 days and new traps were added after 9 days of exposure. Were collected 15.715 insects directly from porcine meat onputrefaction. The results of this study demonstrate a great diversity of Diptera, with nine families, and six families of coleoptera with forensic interest. The most abundant families were, Calliphoridae, Sarcophagidae and Muscidae, Dermestidae and Histeridae in their respective orders
O DESEMPENHO DA MARCHA DE HEMIPARÉTICOS CRÔNICOS E A CORRELAÇÃO COM A RECUPERAÇÃO E O NÍVEL DE COMPROMETIMENTO MOTOR FUNCIONAL
Authors: Haniuda  Moliterno Alice , de  Mello  Padovan Bruna , de  Souza  Viana Juliana , Sampaio  Pereira Andressa , Mayara Guerrero Katiane , Nunes  Gonzaga Caroline , de  Oliveira Damasceno Silas , Bortolin Frasson Isabela , Yassuyuki  Tacao Guilherme , Martins  Barbatto Lucia , Modolo  Regueiro  Lorençoni Roselene , Cesinando de Carvalho Augusto
Published: May 2019

As a result of stroke, impairments such as hemiparesis, gait deficits, impaired motor function and physical deconditioning can occur. In which, gait is one of the most important functional limitations and this way the evaluation becomes important to determine the functional profile and consequently to develop an appropriate treatment. The objective of this study was to evaluate and correlate functional capacity with the level of motor and functional impairment in chronic hemiparetic. This is a cross-sectional study using the Six-Minute Walking Test (6MWT) to assess functional capacity and the Fugl Meyer Protocol (FM) to assess the level of motor and functional impairment. Twelve hemiparetic subjects were included. Statistical analysis revealed no significant correlation between the 6MWT and FM. We conclude that the present study revealed a non-correlation between functional capacity and motor impairment in chronic hemiparetic.
RELAÇÃO ENTRE A PRESENÇA DOS AGENTES COMUNITÁRIOS DE SAÚDE E ADESÃO AO TRATAMENTO DA HIPERTENSÃO ARTERIAL SISTÊMICA
Authors: Phillipe  Cândido  dos  Santos Pablo , Thicyara  Cândida  dos  Santos Waleska , Gonçalves  de Matos Thaís , Costa Castilho Moreira Jaqueline , Sanches Codogno Jamile
Published: May 2019

The objective of this study was to compare adherence to the treatment of systemic arterial hypertension among patients attended at a Basic Health Unit and a Family Health Strategy. The study was conducted in the interior of western São Paulo in 2014, with 200 users aged over 50 enrolled in a Family Health Strategy and a Basic Health Unit. Adherence was assessed by the tests of Batalla and Morisky-Green. Statistical analysis was performed using BioStat software. In the Batalla test, adherence in the Family Health Strategy was 31% and in the Basic Health Unit, 40%. In Morisky-Green, it was 64% in the Family Health Strategy and 68% in the Basic Health Unit. We conclude that there was no significant difference in adhesion according to the unit
ONGs no Brasil: Contextualização Histórica do Cenário para Atuação em Psicologia Escolar
Authors: Galvão Pollianna , Araujo Claisy Maria Marinho
Published: May 2019

Este artigo oferece uma contextualização histórica sobre o percurso de desenvolvimento das organizações não governamentais (ONGs) no Brasil. Atualmente, esses espaços vêm se ampliando no cenário do Terceiro Setor como novo agente social para o atendimento das demandas públicas. O texto parte de uma breve descrição sobre as ONGs educativas no País, como um campo de trabalho emergente ao psicólogo escolar. Em seguida, aborda-se a caracterização histórica sobre as transformações das políticas de Estado, os impactos nas formas de exercício da democracia pela sociedade civil organizada e os desdobramentos à história de origem e consolidação dessas instituições no Brasil. Apresenta-se o atual cenário das ONGs, sinalizando as características político-econômicas que alavancaram o crescimento do número e tipos de serviços prestados por essas entidades nos últimos tempos. Nessa seção, discute-se uma proposta de atuação do psicólogo escolar como possibilidade de trabalho nas ONGs educativas. Por fim, são feitas algumas reflexões sobre os desafios educacionais que se colocam ao psicólogo escolar diante desse novo contexto socioeducativo com potencial para o desenvolvimento humano.
Análise do discurso de um relato publicado acerca de uma prática psicossocial em instituição prisional
Authors: Alvarenga Tamiris Amanda Rezende de , Lombardi Yara , Machado Marília Novais da Mata
Published: May 2019

Neste artigo, analisamos o relato publicado em 2009 de uma prática psicossocial ocorrida numa instituição prisional. Trata-se de um dos trabalhos proveniente de uma investigação mais ampla que considera as dimensões epistemológicas, metodológicas e éticas de práticas psicossociais descritas em periódicos de Psicologia. Nosso objetivo foi analisar o discurso em um artigo científico concernente a uma prática psicossocial. Para isso, alguns critérios nortearam a seleção do texto analisado: ele apresenta uma prática que é simultaneamente de pesquisa e de intervenção, e tanto o método quanto os procedimentos éticos adotados foram explicitados. Investigamos se a prática descrita no referido relato foi capaz de construir operadores conceituais pertinentes, se ela apreendeu a estruturação e o funcionamento institucional em sua complexidade e se produziu conhecimento psicossocial, no que diz respeito à formulação de teoria, de métodos e de dispositivos, tanto de ação quanto de pesquisa.
Análise das queixas escolares considerando o processo de triagem: um estudo em Clínicas-Escola de Psicologia.Análise das queixas escolares considerando o processo de triagem: um estudo em Clínicas-Escola de Psicologia
Authors: Cavalcante Lorena De Almeida , Aquino Fabíola De Sousa Braz
Published: May 2019

O encaminhamento de alunos com queixas escolares a espaços clínicos ou de saúde reflete incompreensão na avaliação de profissionais da escola, que atribuem a causa destas queixas aos escolares ou a suas famílias. Assim, considerou-se pertinente investigar os encaminhamentos de queixas escolares a duas Clínicas-Escola de Psicologia. Para tanto, foram analisadas 3138 fichas de triagem e verificou-se que as queixas escolares consistiram na quarta demanda mais endereçada às Clínicas-Escola, geralmente encaminhadas por familiares ou agentes escolares, inclusive o psicólogo escolar. Questiona-se o fato de queixas escolares serem encaminhadas às Clínicas-Escola, quando deveriam compor uma das ações do psicólogo escolar. Sugere-se uma reestruturação das modalidades de encaminhamento e atendimento a queixas escolares, bem como a reformulação das fichas de triagem, na perspectiva de reverter ações que fortaleçam o paradigma clínico e adaptacionista.
Foucault e a luta antimanicomial brasileira: uma intensa presença
Authors: Lobosque Ana Marta
Published: May 2019

No livro intitulado História da loucura na Idade Clássica, Michel Foucault mostra como o nascimento do asilo, assim como o da disciplina psiquiátrica ali constituída, insere-se em toda uma constelação do castigo e da culpa, tal como veio a configurar-se no fim do século XVIII, a partir de certos rearranjos e mutações das configurações de poder. Sustentando que a análise de Foucault se inspira na perspectiva genealógica nietzschiana, a autora recapitula e comenta algumas das principais teses apresentadas por ele nesse livro. A importância da contribuição do autor na origem e no desenvolvimento da luta antimanicomial brasileira é destacada e interrogadas algumas de suas ressonâncias no cenário da saúde mental e da conjuntura político-institucional no Brasil de hoje.
Alcoólicos Anônimos e a Recaída: Análise à Luz da Experiência Elementar
Authors: Nogueira Dionete Maria Mendes , Júnior Achilles Gonçalves Coelho
Published: May 2019

A recaída é considerada, em alguns estudos, como um processo que compreende tanto o retorno ao consumo da substância química como os momentos anteriores que advertem sobre o risco do abstêmio recidivar. O programa dos Alcoólicos Anônimos (AA) visa à sobriedade através da abstinência total do álcool. O objetivo da pesquisa foi analisar a expressão da experiência elementar no processo de recaída vivenciado por membro de AA, a partir da elaboração da experiência dos sujeitos. Trata-se de pesquisa qualitativa, cuja coleta de dados deu-se mediante entrevistas semiestruturadas, das quais participaram cinco membros de AA de três grupos de Montes Claros-MG. Empregou-se a análise fenomenológica para o tratamento dos dados, via que possibilitou a apreensão de quatro categorias temáticas: Pertencimento; Posicionamento Pessoal; Exigência de Ser e Experiência Religiosa. A dinâmica da experiência elementar do alcoolista, expressa no processo de recaída, orienta o posicionamento do mesmo diante de si e do mundo.
Ancoragem psicossocial a partir dos sentimentos negativamente valorados: representações sociais de ciganos
Authors: Brasil Julia Alves , Bonomo Mariana , Nascimento Amandha Gyselle Martins , Livramento André Mota , De Souza (in memoriam) Lídio
Published: May 2019

Tendo como referência a abordagem não consensual da teoria das representações sociais, este trabalho teve como objetivo investigar como se articulam as representações sociais e a dimensão afetiva associadas ao objeto social “ciganos”, entre população não cigana da Grande Vitória-ES. Foram desenvolvidos dois estudos complementares com (1) 108 estudantes universitários e (2) 10 sujeitos que associaram sentimentos de valoração negativa aos ciganos. A coleta dos dados foi realizada por meio da aplicação de questionário e de entrevista em profundidade, e o tratamento das informações obtidas foi conduzido com o auxílio dos softwares SPAD-T e Alceste. Os resultados indicaram a (re)produção de estereótipos negativos vinculados aos ciganos e a dimensão afetiva fortemente marcada por medo e aversão, núcleo de preconceito e discriminação contra os ciganos.
A África Antiga sob a ótica dos clássicos gregos e o viés africanista
Authors: Candido Maria Regina
Published: May 2019

A Lei n.º 10.639/2003 foi resultado do empenho de pesquisadores, professores e educadores africanistas, conscientes da necessidade de inserir o tema de forma inclusiva junto à sociedade brasileira. Por meio de citações provenientes dos clássicos gregos, podemos cotejar informações sobre parte da África e estabelecer uma abordagem comparativa entre a cultura helênica e a dos negros africanos conhecidos pelos antigos gregos. Os vestígios textuais e a cultura material, ambos associados às historiografias antiga e atual, nos permitem focalizar a África Antiga sob o viés afrocentrista. O tema transita pela atualidade, suscita questões e debates, assim como nos traz à tona a história da antiguidade africana como tema de pesquisa inserida na disciplina de História Antiga.
Apresentação – Dossiê História e Historiadores
Authors: Cedro Marcelo De Araújo Rehfeld
Published: May 2019

Apresentação dos Cadernos de História, v. 19, n. 30, 1º semestre 2018.
Desempenho econômico-produtivo dos principais agronegócios da Mesorregião do Oeste Catarinense (2000-2016) / Economic and productive performance of main agribusinesses of the Western Santa Catarina Mesoregion (2000-2016)
Authors: Von Dentz Eduardo , Espíndola Carlos José
Published: May 2019

Após o processo de reestruturação produtiva pelo qual passou a agricultura brasileira, datado da década de 1960 em diante os anos 2000 apresentaram um ciclo de crescimento da economia condicionado por fatores internos e externos. Nesse contexto, os agronegócios tiveram importante participação na composição da base geoeconômica do país. Na mesorregião Oeste de Santa Catarina, recorte espacial do presente artigo, entre os anos 2000 e 2016, as lavouras temporárias foram responsáveis por mais de 47% do valor bruto da produção de todo o estado, enquanto as lavouras permanentes somaram mais de 36% do total estadual. Com isso, identificar o comportamento, em termos de representação econômica, na mesorregião Oeste catarinense, das principais lavouras permanentes e temporárias, é o objetivo central deste texto. Buscou-se alcançar o objetivo com base nos indicadores de área colhida, quantidade produzida e valor bruto da produção. Assim, as áreas agrícolas apresentaram profundas transformações na estrutura produtiva da região, havendo um crescimento das lavouras temporárias, sobretudo da soja, em detrimento das lavouras permanentes, sobretudo as de abacate, goiaba, limão e pera.Palavras–chave: Especialização produtiva. Lavouras temporárias. Lavouras permanentes. Oeste catarinense.Abstract After the productive restructuring process that the Brazilian agriculture experienced from the 1960s onwards, the 2000s presented a cycle of economy’s growth conditioned by internal and external factors. Thus, the agribusinesses had significant participation in the composition of the country's geo-economic base. Between 2000 and 2016, in the western mesoregion of Santa Catarina, which is the present article’s space cut, temporary plantations accounted for more than 47% of the gross production value of the whole state while the permanent crops accounted for more than 36% of the state total. Therefore, the primary objective of this text is to identify the behaviour of permanent and temporary crops regarding the economic representation, in the western mesoregion of Santa Catarina. It was possible to achieve the goal through the harvested areas indicators, quantity produced and production gross value. Thus, the agricultural areas underwent profound transformations in the region’s productive structure. Temporary crops, especially soybeans, grew at the expense of permanent crops, mainly avocados, guavas, lemons, and pears.Keywords: Production specialization. Temporary crops. Permanent crops. West of Santa Catarina
A Hemorrede pública do Leste de Minas: territorialização, demanda e capacidade de atendimento / The public blood banks of the eastern Minas Gerais: territorialization, demand and capacity of attendance
Authors: Rocha Sylvia Fátma Gomes
Published: May 2019

Este trabalho – A hemorrede pública do Leste de Minas: territorialização, demanda e capacidade de atendimento – tem como objetivo apresentar o Hemocentro Regional (HR), na cidade de Governador Valadares, que atua nas macrorregiões Leste e Nordeste de Minas Gerais.  Foi realizada uma avaliação sobre sua capacidade de atendimento na perspectiva de compreensão de sua territorialização e da demanda da população referência. A avaliação foi realizada a partir de análise de dados fornecidos pelo próprio HR para os anos 2012 a 2016, incluindo-os. Concluiu-se pela necessidade de nova pactuação entre os atores correlacionados para melhoria do atendimento hemoterápico na região.Palavras-chave: Hemorrede, territorialização, leste de Minas, demanda, atendimento.AbstractThis work aims of the present in Regional Hemocenter (HR), in The Governador Valadares’city with, operates in the east and northeast macroregions of Minas Gerais. An evaluation was made of their capacity to serve in the perspective of understanding their territorialization and the demand of the reference population. The evaluation was performed based on data analysis provide by HR itself for the years 2012 to 2016, including them. It was concluded that there was a need for a new agreement among the correlated actors to improve chemotherapy in the region.Keywords: Blood banks, Territorialization, east of Minas Gerais, demand.
“Aqueles que ainda resistem”: um olhar sobre as disputas territoriais associadas ao processo de regularização fundiária do Parque Nacional da Serra do Cipó, MG, Brasil / “Those who still resist”: a look on territorial conflicts associated with the process of land regularization at National Park of Serra do Cipó, MG, Brazil
Authors: Sancho Pivoto Altair
Published: May 2019

No Brasil, muitas unidades de conservação (UCs) ainda não possuem seus processos de regularização fundiária concluídos. Como resultado, muitas dessas áreas registram até hoje situações de disputas e conflitos, aspecto que complexifica os processos de gestão e conservação da biodiversidade, bem como, interfere diretamente na manutenção de exercícios de territorialidade de muitos moradores. Inspirados nesse contexto, o presente trabalho tem por objetivo analisar a situação fundiária do Parque Nacional da Serra do Cipó (MG), criado em 1984, bem como os processos de disputa territorial associados. Ancorada em um viés qualitativo, a presente investigação envolveu pesquisa bibliográfica e documental, além de entrevistas com analistas do parque e com uma moradora que ainda resiste em permanecer em suas terras, mesmo após a criação do parque.Palavras-chave: Unidades de Conservação, Parques, Conflitos Ambientais, Serra do Cipó (MG)Abstract In Brazil, many conservation units (UCs) still do not have their processes of land regularisation completed. As a result, a lot of them coexist with cases of territorial conflicts, a situation that gives complexity to the management and biodiversity conservation processes, at the same time, interferes directly in the maintenance of territorial practices of some residents. This research aims to analyse the land regularisation at National Park of Serra do Cipó (MG), created on1984, and then some processes of territorial conflicts associated. Based in a qualitative perspective, this investigation involves bibliographic and documental surveys and interviews with park’s employees and a resident who still resists remaining on her lands, even after the creation of the park.Keywords: Conservation units, Parks, Environmental, Serra do Cipó (MG)
Aplicabilidade de Protocolos de Avaliação Rápida (PARs) no diagnóstico ambiental de sistemas fluviais: o caso do Parque Nacional da Serra do Gandarela (MG) \ Applicability of Rapid Assessment Protocols to the environmental diagnosis of river systems: the case of the Serra do Gandarela National Park (MG)
Authors: Rosa Nayara Mariana Gonzaga , Magalhães Júnior Antônio Pereira
Published: May 2019

Os processos decisórios de gestão de bacias hidrográficas dependem de informações qualificadas, pautadas na realidade e diversidade dos sistemas hídricos.  No Brasil, o diagnóstico ambiental de sistemas fluviais baseia-se principalmente em análises realizadas através de estações de monitoramento. Estas avaliações, no entanto, apresentam alto custo e consideram apenas parâmetros físico-químicos e bacteriológicos da água, desconsiderando aspectos morfológicos, sedimentológicos e ecológicos. Frente a esta limitação, torna-se desejável a utilização de ferramentas práticas, que permitam uma análise ambiental pouco onerosa e integrada de cursos d’água. Diante deste contexto, o presente estudo teve como objetivo conceber um Protocolo de Avaliação Rápida (PAR) para aplicação em sistemas fluviais do Parque Nacional da Serra do Gandarela (MG) e discutir suas potencialidades como instrumento de suporte ao monitoramento e gestão de recursos hídricos. Os resultados demonstraram que o PAR pode ser considerado como uma ferramenta viável, já que a partir de sua aplicação foi possível detectar, de forma rápida e prática, alterações gradativas na qualidade ambiental do curso d’água avaliado.Palavras–chave: Protocolos de Avaliação Rápida, Gestão de sistemas fluviais, Avaliação ambiental, Qualidade ambiental.Abstract Decision-making processes for river basin management depend on qualified information, based on the reality and diversity of water systems. In Brazil, the environmental diagnosis of river systems is based mainly on the analysis carried out through monitoring stations. These assessments, however, present high costs and consider only physical-chemic and bacteriological water parameters, disregarding morphological, sedimentological and ecological aspects. Faced with this limitation, it is desirable to use practical tools that allow a cheap and integrated evaluation of river systems. In this context, the present study aimed to design a Rapid Assessment Protocol for application in river systems of the Serra do Gandarela National Park (MG) and to discuss its potential as an instrument to support the monitoring and management of water resources. The results showed that the protocol could be considered a viable tool, since from its application it was possible to detect, quickly and practically, gradual changes in the environmental quality of the evaluated watercourse.Keywords: Rapid Assessment Protocols, Fluvial systems management; Environmental Assessment; Environmental quality.
A degradação ambiental em narrativas de naturalistas do século XIX para a reserva da Biosfera da Serra do Espinhaço / Environmental degradation in narratives of naturalists of the 19th century for the Espinhaço Range Biosphere Reserve
Authors: Mucida Danielle Piuzana , Gontijo Bernardo Machado , De Morais Marcelino Santos , Fagundes Marcelo
Published: May 2019

A região central do estado de Minas Gerais, especificamente o Quadrilátero Ferrífero e a Serra do Espinhaço Meridional, é marcada pela ocupação em busca de riquezas minerais tais como diamante e ouro. Possui, ainda, relevância ecológica, o que levou a declaração desta região, pela Unesco em 2005, como Reserva da Biosfera da Serra do Espinhaço. Vislumbrou-se, nesse artigo, a caracterização e análise de processos de degradação ambiental em literatura de viagem de naturalistas estrangeiros que percorreram esta região no século XIX. Trabalhos de campo ocorreram em roteiros estabelecidos a partir da leitura das obras, com enfoque no entendimento da paisagem. Evidências de degradação ambiental pelo extrativismo mineral do ouro e diamante, apresentadas nas narrativas em áreas dos caminhos da Estrada Real, caracterizam-se pela supressão da vegetação nativa por meio de queimadas, mudança/desvio de cursos fluviais, uso de mercúrio para beneficiamento mineral além de ocorrência significativa de espécimes monotípicas invasoras, como o capim-gordura e a samambaia. O estudo, pela descrição analítica em relatos de naturalistas viajantes analisados no território da reserva da biosfera, permite um resgate memorial que vincula o ser humano à natureza, como parte de sua história ambiental.Palavras-chave: relatos de viajantes, mineração, mercúrio, queimadas, capim-gordura.AbstractThe central region of Minas Gerais state, specifically the Iron Quadrangle and the Southern Espinhaço Range, has a unique occupation history due to mineral riches such as diamond and gold. Furthermore, it has significant ecological relevance, which has led to the declaration of the Espinhaço Range Biosphere Reserve by Unesco in 2005. To characterise and analyse the historical processes of environmental degradation of this region, the travel literature of foreign naturalists who travelled throughout the region in the 19th century was investigated. The research involved studying scripts produced from reading works, with a focus on the understanding of the landscape. Evidence of environmental degradation by gold and diamond extractivism is presented in several areas of the Estrada Real, characterised by the suppression of native vegetation by anthropic burning, change of river courses and use of mercury for mineral processing, in addition to a significant occurrence of invasive monotypic species, such as molasses grass and fern. From the analytical description in reports of travelling naturalists, the analysis of the reserve territory of the present study allows the recovery of part of a memory that binds human to nature as part of its environmental history.Keywords: travellers’ accounts, mining, mercury, burning, molasses grass.
A RETÓRICA CONSTITUCIONAL E OS PROBLEMAS DOS LIMITES INTERPRETATIVOS E ÉTICOS DO ATIVISMO JURISDICIONAL NO BRASIL
Authors: Adeodato João Maurício
Published: May 2019

Este texto pretende expor as teses colocadas no sumário, ou seja, como a dissociação entre texto e decisão jurídica trazida pela sociedade complexa provoca uma pulverização das convicções éticas e das instâncias decisórias, sobrecarregando o direito e, dentro do direito, o poder judiciário. E, no contexto de um país que tem os problemas da grande complexidade social, mas não consegue efetivar as soluções e instituições criadas para lidar com eles no mundo ocidental desenvolvido, mostrar que é preciso construir limites interpretativos e éticos para uma jurisdição constitucional democrática no Brasil.Na base dessas teses, os problemas centrais da filosofia do direito podem ser resumidos em três perguntas. A primeira diz respeito ao conhecimento: como detectar o que se chama de direito e separá-lo daquilo que não é considerado direito. A segunda trata do aspecto ético ou valorativo do direito: se suas criação, interpretação e aplicação estão à disposição do poder que governa ou se há instâncias e critérios superiores, ou seja, se há distinção entre direito e justiça. A terceira é metodológica, sobre como a filosofia do direito deve proceder: se tem a função de descrever como o direito se mostra empiricamente ou de aconselhar as demais pessoas sobre o que o direito deveria ser, na opinião de cada filósofo.
A TRIBUTAÇÃO PROGRESSIVA DA RENDA E A REDISTRIBUIÇÃO DA RENDA: O CASO DO BRASIL
Authors: Caliendo Paulo
Published: May 2019

O objetivo do presente artigo é verificar a pertinência e validade da tese de que a tributação elevada sobre o capital e a riqueza se constitui em um mecanismo ótimo para a redistribuição de renda.
ALIENAÇÃO PARENTAL: A RESPONSABILIZAÇÃO DO ENTE ALIENADOR POR MEIO DA PRÁTICA RESTAURATIVA
Authors: Malta Rafaella Rodrigues , Rodrigues Júnior Walsir Edson
Published: May 2019

O presente trabalho tem como objetivo expor como se configura a alienação parental e como a prática restaurativa de processos circulares se traduz em uma possibilidade legítima, efetiva e transformadora do conflito da alienação parental, visando à reparação dos danos e à responsabilização ativa do ente alienador. A hipótese é que, diante da complexidade desse fenômeno familiar, torna-se possível empregar a prática restaurativa de processos circulares como método autônomo de resolução de conflitos extrajudicial para promover o acesso a uma ordem jurídica justa. Dessa forma, atento se estaria à Doutrina da Proteção Integral da Criança e do Adolescente apregoada na Constituição de 1988 e no Estatuto da Criança e do Adolescente (Lei n. 8.069/90).
DIREITOS FUNDAMENTAIS NA PÓS-MODERNIDADE SOB A PERSPECTIVA DA ANÁLISE ECONÔMICA DO DIREITO
Authors: Borges de Oliveira Emerson Ademir , Payão Jordana Viana
Published: May 2019

A concretização dos direitos fundamentais é pauta de tradicionais debates jurídicos. A pós-modernidade, contudo, introduziu denominadores inéditos na dinâmica dos direitos fundamentais e, frente aos crescentes fenômenos da erosão da consciência constitucional e as necessárias escolhas trágicas. O objetivo do presente artigo é convidar a uma reflexão interdisciplinar do referido contexto sob a perspectiva da análise econômica do Direito, aliado ao método dialético-jurídico e à pesquisa bibliográfica nacional e estrangeira.
Unternehmensbezogene Außenkommunikation des Aufsichtsratsvorsitzenden
Authors: Reutershahn Laura
Published: May 2019

Company-related external communication by the German chairman of the supervisory board (“Aufsichtsratsvorsitzender”) can lead to corporate law questions: The author particularly analyses the competence of the German “Aufsichtsrat” as well as the chairman’s role regarding company-related external communication in the meaning that the author defines.
Information Literacy Faculty Fellows program: Building a faculty-librarian framework community of practice
Authors: Crowe Stephanie , Pemberton Anne , Yeager Vonzell
Published: May 2019

The Framework for Information Literacy for Higher Education (Framework) calls upon librarians to think of information literacy as a concept to be applied beyond the one-shot session, suggesting that the “Framework…is intended to be developmentally and systematically integrated into the student’s academic program at a variety of levels.”
Washington Hotline
Authors: Russell Carrie
Published: May 2019

Librarian of Congress appoints new Register of CopyrightsOn March 27, Librarian of Congress Carla Hayden appointed Karyn Temple the new Register of Copyrights. “Karyn has done a superb job as acting register for the last two-and-a-half years, leveraging her skills as both a copyright lawyer and accomplished manager to provide excellent leadership for the Copyright Office,” said Hayden. “Of the 13 Registers of Copyright in U.S. history, Temple will be the first person of color to hold this position.”
Modern students' mental representations of success
Authors: A. Kibal'chenko Irina , V. Eksakusto Tatiana
Published: May 2019

The research is aimed at studying the success mental representations of students who are considered as the modern society members seeking for intellectual and personal resources integration. The article describes relevance and prospects of the success mental representations studying. These representations are considered to reflect personal real and potential success. Such methods as content and statistical analyses are used for the research. Quantitative analysis of signs/indices (total quantity: 555) and categories (total: 415) allowed the “success” concept cognitive structure characterizing. Categorizing the analyzed units helped to define modalities which become basic in the research and specified its conceptual scheme. Quadri classification of signs helped to find out the “success” concept organization style, having peculiarities based on the speed and accuracy of these signs selection, their structuring and integration. The summary of the research is based on the statistically significant conclusions. The level of the students’ style cognitive and personal characteristics structuredness is determinantial for the success mental representations structural organization. The more complete and integral the success cognitive image is, the more mature and integrated the students’ personal resource and experience are; in this case the students are highly motivated for reaching the success. The results of this research elaborate the idea and scientific facts about mental representations and can be informative and useful for cognitive psychology researchers and the persons working with students.
Thinking styles and computer engineering training: An empirical study
Authors: Huincahue Jaime , Gaete-Peralta Claudio , Viviana Garrido Véliz
Published: May 2019

This study shows the qualitative construction of a Referential Cognitive Graduate Profile (RCGP) for the Computer Engineering program of the University of Bernardo O’Higgins (UBO) in Chile, based on the theory of Mental Self-Governance and by using three data-gathering methods: document analysis, interviews, and questionnaires, reflecting the profes-sional competencies expected by the end of the training, set forth by both the institution and program management. The proposed model allows to contrast the different thinking styles (TSs) found with the ones preferred by students in different levels of formation independently. With this purpose in mind, by using a quantitative methodology, 88% of male students in the program completed the questionnaires to determine these preferences, enabling us to perform a correspondence analysis through Fisher’s exact test. The RCGP results show evident preference for the legislative, executive, hierarchical, and external styles of thinking and clear differences between the preferences of students and of the RCGP. Finally, we discuss about various ways to create new means to strengthen and upgrade both the program’s graduate profile and the RCGP with the purpose of benefitting the formation of Computer Engineers and the future of the RCGP model.
Identification of cognitive manipulations that have the greatest impact on students in the internet
Authors: Zhdanko Anna
Published: May 2019

The study puts an emphasis on exploring cognitive manipulations contained in the Internet resources (social networks and blogs) that have the greatest impact on students. The study was conducted with 159 students of Don State Technical University. 50 samples of media texts (of various formats) containing cognitive manipulation were taken from social networks sites and blogs. Focus group method, questionnaire, method of Critical Discourse Analysis and methods of mathematical statistics (Principal Component Analysis) were used for data collection and processing. The findings allow us to identify and describe the features of such cognitive manipulation as “presence effect”, “focus on pros”, “halo effect”, “emotional resonance”, “ambiguous language”, “anonymous authority”, “primacy effect”, “exaggeration” and identify the manipulations that have the greatest impact on students. Recommendations aimed at reduction of the impact of manipulative techniques were suggested. The results of the present study may help teachers and psychologists in their work.
Content analysis of master's degree and doctorate theses where social skills training is approached
Authors: Tezer Murat , Şebnem Kan Güldal , Öznacar Behçet , Şensoy Şeniz , Çaltıkuşu Çilem
Published: May 2019

Social skills play an important role in interpersonal social skills. This study investigates social skills training concept in general sense in articles, master and doctorate degree programs. Literature review was made in the research between the years 2010-2017. In this literature review process the concepts of publication type, subject area, publication year, research design, data collection tool, sample group, province and department concepts were discussed for social skills training. Study group meta-analysis technique was used in this research. Thirty-eight articles and the theses existing in 22 master’s degree and 21 doctorate program in Turkish Council of Higher Education National Thesis Centre and Google Scholar were analysed.
Studying the welfare of children at an early age in the system of institutional care
Authors: Dermendzhieva Sofya
Published: May 2019

This article discusses the need to develop a unified vision and strategy for enhancing the welfare of children at an early age in the institutional care system in Bulgaria. The methodological basis for the research is the “Quality Framework for Early Childhood Services” (QFECS) of the International Association Step-by-Step (ISSA). A diagnostic tool was developed that explores the guiding principles of good practices in nine different priority areas in three distinct groups in Bulgaria. It analyzes the state of early care and identifies the resources that ensure the quality of services during early childhood.