bluuebunny/crossref_metadata_2025 huggingface dataset:
KARAKTERISTIK PEMBERIAN OBAT GOLONGAN BETA BLOCKER PADA PASIEN GAGAL JANTUNG YANG MENJALANI PERAWATAN DI RSUD DR. H. CHASAN BOESOIRIE PADA TAHUN 2019
Authors: WIDURI MARWAH
Published: January 2022

Dalam Profil Kesehatan Indonesia 2008 disebutkan bahwa gagal jantung menyebabkan 13.395 orang menjalani rawat inap dan 16.431 orang menjalani rawat jalan di seluruh rumah sakit di Indonesia, terbanyak ketiga pada kelompok pasien penyakit jantung, serta mempunyai persentase Case Fatality Rate sebesar 13,42%, kedua tertinggi setelah infark miokard akut (13,49%). Berarti dapat disimpulkan bahwa gagal jantung termasuk dalam penyakit yang banyak diderita oleh masyarakat dan berakibat dalam hal penurunan kualitas hidup. Secara internasional, pengobatan untuk pasien gagal jantung mengacu pada pedoman yang dirilis oleh European Society of Cardiology (ESC) dan The American College of Cardiology Foundation (ACCF) – American Heart Association (AHA). Pedoman terapi yang disusun meliputi terapi medikamentosa dan non-medikamentosa. Kata Kunci : Gagal Jantung, Obat Golongan Beta Bloker, Rumah Sakit Chasan Boesoirie
PROFIL KUALITAS KESEHATAN MASYARAKAT KEPULAUAN DI PULAU MOTI
Authors: THE FERA
Published: January 2022

ABSTRAKMasyarakat yang hidup di pulau-pulau kecil cenderung memiliki tingkat kesehatan yang rendah disebabkan antara lain karena kurangnya ketersediaan air bersih dan berkualitas, minimnya ketersediaan makanan yang bergizi dan terbatasnya pelayanan kesehatan. Penelitian ini bertujuan untuk mengetahui profil kualitas kesehatan masyarakat di Pulau Moti. Penelitian dilakukan dengan mengumpulkan data primer, yaitu dengan pengamatan secara langsung dan melalui angket yang berisi pertanyaan serta data sekunder, yaitu data dari sarana kesehatan. Pada penelitian ini telah terkumpul data sebanyak 100 sampel. Hasil penelitian menunjukkan bahwa kualitas kesehatan masyarakat di Pulau Moti masih kurang baik. Hal ini dilihat dari beberapa faktor, yaitu belum tersedianya jamban pribadi di setiap rumah, belum adanya tempat pembuangan sampah akhir dan tempat sampah tertutup di setiap rumah, kebiasaan membakar sampah, kebiasaan merokok, tidak rutin konsumsi buah dan sayur, tidak rutin berolahraga, serta kurangnya kebiasaan mencuci tangan sebelum dan sesudah makan, serta masih banyak keluarga yang belum memiliki BPJS. Kata kunci:  Kesehatan, Masyarakat, Pulau Moti
KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIS YANG MENJALANI HEMODIALISIS DI RSUD CHASAN BOESOIRIE TERNATE
Authors: RISKY FATHUL
Published: January 2022

Introduction. Chronic kidney disease (CKD) as a result of structural and functional renal failure has a high progressivity leading to an end stage renal disease (ESRD), thus a therapy is needed to replace the renal function such as hemodialysis. Long term hemodialysis therapy affects many aspects of life and degrading the quality of life of the patient. Method. This cross-sectional study was conducted at Chasan Boesoirie Hospital, Ternate. Primary data, such as socio-demography were taken through history taking and medical records. Quality of life was assessed using Kidney Disease Quality of Life - Short Form (KDQOL-SF)-36 TM which has been used to measure quality of life of patients undergoing hemodialysis. Results. From this study a sample of 77 patients was obtained, of which 41 were male (53.25%) and 36 were female (46.75%). Of the three quality of life components assessed, KDCS components were 78.65 ± 13.39; the MCS component 54.67 ± 7.53; and PCS components 42.47 ± 7.76. Conclusions. From the results of the study it was found that the highest KDQOL-36TM score was obtained for the kidney disease component (KDCS), then the mental health component (MCS), and the lowest score for the physical health component (PCS). Of all the variables hypothesized to affect the quality of life of kidney failure patients undergoing hemodialis, not a single variable was found to be significantly affected (P value> 0.05).Keywords: end-stage renal disease, hemodialysis, quality of life.
KORELASI ANTARA HASIL TES MIKROSKOPIS DENGAN TES CEPAT MOLEKULER PADA PASIEN TUBERCULOSIS DAN MULTIDRUG RESISTEN TUBERCULOSIS DI RSUD Dr. H CHASAN BOESOIRIE TERNATE
Authors: Afiah Andi Sitti Nur , The Fera
Published: January 2022

Tuberculosis (TB) is a pulmonary disease caused by Mycobacterium tuberculosis. Globally in 2018 theestimated number of people affected by TB was estimated at 10.0 million population and 484,000 cases ofmultidrug-resistant TB (MDR-TB). This study aims to determine the correlation between microscopic testresults with RMT on TB and MDR-TB patients at RSUD Dr. H Chasan Boesoirie Ternate. This type of researchis analytical research using a retrospective approach. The sample in this study were patients with suspected TBand MDR-TB who had performed microscopic tests and TCM in February – April at 2020 in the ClinicalPathology Laboratory of RSUD Dr. H Chasan Boesoirie Ternate, who met the inclusion and exclusion criteria.Data were analyzed using the SPSS program analysis was carried out in stages, namely by univariate andbivariate using chi-square test. From 100 samples, the results of RMT examination with TB suspects were 30rifampicin sensitive samples with 2 rifampicin resistance and 5 rifampin sensitive samples for TB MDR-TBsuspects RMT examination results. Chi-square test results obtained the value of p = 000 (p <0.05). There is stilla significant difference between the microscopic test results with RMT in TB and MDR-TB suspect patients atRSUD Dr. H Chasan Boesoirie Ternate.
HUBUNGAN PEMBERIAN ASI EKSKLUSIF DENGAN TINGKAT INTELLIGENCE QUOTIENT (IQ) DI KLINIK ANANDA KOTA TERNATE
Authors: Hasan Marhaeni , The Fera
Published: January 2022

Air Susu Ibu merupakan makanan bayi utama dan alami, ASI dengan komposisi yang unik yangsesuai dengan kebutuhan tumbuh kembang bayi. ASI eksklusif adalah ASI yang diberikan kepada bayisejak dilahirkan selama enam bulan, tanpa menambahkan dan/atau mengganti dengan makanan atauminuman lain. Pemenuhan nutrisi saat bayi terutama ASI merupakan salah satu faktor yangmempengaruhi kecerdasan anak. Tujuan penelitian untuk mengetahui hubungan pemberian asi ekslusifdengan tingkat Intelligence Quotient (IQ) di Klinik Ananda Kota Ternate. Populasi penelitian adalahsemua siswa sekolah dasar kelas I-VI. Jumlah responden sebanyak 50 Orang yang datang ke klinikAnanda, setelah itu menetapkan sampel berdasarkan kriteria inklusi dan, Jenis penelitian ini adalahobservasional dengan menggunakan pendekatan Cross Sectional. Penelitian ini menggunakan metodekuantitatif dengan cara accidental sampling. Penelitian ini menunjukan bahwa tidak adanya hubunganyang signifikan antara pemberian ASI eksklusif dengan tingkat IQ berdasarkan hasil uji statistik SPSSdengan menggunakan Chi-square dimana didapatkan p Value = 0.802. Tidak didapatkan hubungan yangsignifikan antara pemberian ASI eksklusif dengan tingkat IQ.Kata kunci : Air Susu Ibu, ASI eksklusif, kecerdasan
Health Care Providers' Knowledge and Attitudes in Perinatal Care for Women with Disabilities
Authors: Sarantaki Antigoni , Vasiliki Zambeli Maria , Diamanti Athina , Lykeridou Aikaterini
Published: January 2022

Background: Disability is a global phenomenon counting more than one billion people reaching the percentage of 15% of the population worldwide and it will be rising constantly in the coming years. Women with disabilities are getting pregnant more and more. Although perinatal care has been extensively researched and is constantly being improved for women without disabilities, health care professionals are not adequately educated and fully experienced for caring for pregnant women with disabilities. As a result of that they are negatively inclined towards disabled women. Objective: The purpose of this review is to investigate health care providers’ behaviors and attitudes towards women with disabilities whilst providing perinatal care. Conclusion: Overall, it seems that health care providers feeling insecure and not confident in providing perinatal care to women with disabilities which results in them having negative attitudes and behaviors. This stems from the inadequate knowledge they have about disability conditions and pregnancy. Upgrading their training and education from undergraduate level is an urgent need. Constant contact with disabled patients seems to be a beneficial factor for better treatment.
Mortality Associated Factors of Patients with Mechanical Ventilation Treated at the Intensive Care Unit of a Second Level Hospital at Piedras Negras Coahuila Mexico
Authors: Molina Serrano Jose Ivan Rodriguez de
Published: January 2022

Introduction: The mechanical ventilation is the cornerstone of treatment for patients with acute respiratory failure and is one of the pivotal therapies in critical care medicine. The epidemiology of mechanical ventilation in México is scarce and usually a transpolated of the information in high specialty centers. The mechanical ventilation has the aim of assisting in the elimination of CO2 (carbon dioxide) and / or favoring the adequate exchange of oxygen while the patient is unable to do so or due to conditions external to the respiratory system. Quality indicators of attention are a quantitative measure that are used to assess important aspects of clinical practice. Objective: Describe the epidemiology and mortality factors in mechanically ventilated patients treated at second level ICU in Piedras Negras, Coahuila México. Material and Methods: retrospective study from December 2016 to December 2019 all patients treated with MV. We collected general demographic characteristics, quality indicators and complications, severity of disease and mortality. Results: 164 patients were enrolled. Female 54.8%, main diagnoses Sepsis 30.5%, and DKA 13.4%, mean age 44.1 SD ± mean SOFA 7.2 SD ± 6.2, mean SAPS3 50.6 SD ± 20.2, ICU LOS 4.5 SD ± 5.1, Hospital LOS 11.7 SD ± 10.2 p<0.0001. ICU and Hospital mortality 14 % and 23.8%. The factors associated with ICU mortality were: Age, MV hours, Respiratory SOFA, and Hepatic SOFA and with Hospital mortality: Age, Neurological SOFA, Unstable at admission, SOFA and SAPS 3. Conclusions: MV is a primordial need of critical care patients, our mortality was reported lower than expected but quality of attention indicators most be improved in order to maintain this trend. This study has several limitations in population and applicability but contributes with primordial information about MV critical care patients treated at México.
The Impact of Diagnostic MRI on the Early Detection of Lethal Genes in Human Genome and to Develop Genomic Medicine to Treat Brain Cancers
Authors: Khan A Hameed
Published: January 2022

Early detection of the onset of diseases are essential if we want to maintain good health. MRI technique provides a three-dimensional image of a microscopic lesion in an organ. Human body is made of 220 different tissues which interact to make an organ and several organs interact to make a human. As a part of medical record, taking MRI of each organ every year and comparing them with each other will identify the appearance of microscopic changes. For example, if you are diagnosed with Brain cancer today, you did not get the cancer yesterday. Abnormal changes are the result of accumulation of harmful mutations over the years predicting the onset of diseases. Once the brain tumor is confirmed, the patient dies within fourteen months. To save the life of the patient, the following three strategies are available and they are Surgery, Radiation and Chemotherapy. This article describes the Chemotherapeutic approach to treat cancers in general and brain cancer, Glioblastoma, in particular. Using rational approach, we designed AZQ (US Patent 4,146,622 & 4,233,215) to treat Glioblastomas. MRI Would identify appearance of microscopic lesions of Glioblastoma and help us start treatment with AZQ long before the disease is confirmed. Using similar rational approach of early diagnosis with MRI, we could design drugs to treat other diseases including cancers.
Retrospective Study on Hospital Admissions due to Pyelonephritis in Type II Diabetic Patients
Authors: Dhillon Dilraj , Randall Thomas , Zezoff David , Bhattacharyya Mouchumi
Published: January 2022

Background: Pyelonephritis is a urinary tract infection that ascends to involve the kidneys. It can also occur as an infection secondary to bacteremia. Some pathogens that commonly cause pyelonephritis are E. coli, enterobacteriaceae, staphylococci, and pseudomonas. The initial patient presentation usually involves fever, chills, nausea, vomiting, costovertebral angle tenderness, and flank pain. Other cystitis symptoms such as dysuria, increased urinary frequency, malodorous urine, and hematuria may or may not be present. Symptoms of pyelonephritis with bacteriuria are sufficient for the diagnosis of pyelonephritis. Aim: The aim of this study was to investigate a potential link between Type II Diabetes Mellitus and pyelonephritis. Methods: In this retrospective study, hospitalized patients during the study period were reviewed. Variables examined were sex, age, and length of stay. Patients were excluded if they had known urogenital abnormalities, indwelling catheters (Foley, nephrostomy, suprapubic, or who regularly perform clean intermittent catheterization), were pregnant, or were on dialysis. Results: Of 333 patients analyzed, diabetics had a longer length of stay then non-diabetics (4.49 vs 3.67 days respectively; p=0.0041) and females were significantly younger than men in hospitalized patients for pyelonephritis were (50.0 vs 63.5 years; p=<0.0001). Further, it was found that diabetics were significantly older than nondiabetics were (60.4 vs 47.3; p=<0.0001) and more diabetics getting admitted with pyelonephritis were men vs women (59.32% vs 35.27%; p=0.0007). Conclusion: Results of the study were significant in showing that of all pyelonephritis-hospitalized patients on average the length of stay was longer for diabetics and it demonstrated that female patients with pyelonephritis are significantly younger than male patients hospitalized with pyelonephritis. Of note, there was no significant difference in the length of stay for diabetic patients based on their treatment modality (diet controlled vs. oral medications vs. insulin dependent vs. combined). The study also showed that diabetics getting admitted for pyelonephritis are more men and older in age compared to the nondiabetics.
Intensity Modulated Radiotherapy in Complex Treatment of Leptomeningeal Disease of Extracranial Solid Neoplasms
Authors: Marinova Lena , Georgiev Radoslav , Evgeniev Nikolay
Published: January 2022

Leptomeningeal metastases (LM) are a severe consequence of metastatic distribution of solid malignant tumors. The purpose of this article is to highlight the importance of the intensity modulated radiotherapy (IMRT) to achieve prolonged local tumor control (LTC) in patients with LM. We present five clinical cases of leptomeningeal disease (LMD) in two patients with breast cancer (BC) and and in another three with malignant melanoma, laryngeal and renal carcinoma. The healing results after intensity modulated whole-brain radiotherapy (IM-WBRT) up to TD 40 Gy with DD 2 Gy, followed by boost radiotherapy (boost-RT) up to TD 50 Gy-54 Gy in the bulky brain metastases was presented. In BC LMD, the concominant RT with targeted therapy (TT) of trastuzumab and denosumab was performed. Leptomeningeal metastases have a poor prognosis, but precise IMRT with the realization of tolerant doses in normal brain structures and cancericidal doses in pathological brain areas achieves prolonged LTC for one year after RT with good quality of life. LMD in solid tumors requires an individual radiotherapeutic approach on a different target volume and necessary radiation doses, depending on the histological characteristic of tumor cells, as well as on the volume and localization of leptomeningeal metastases.
A Real Data-Driven Analytical Model for Testing for the Novel Coronavirus Disease, COVID-19
Authors: Tsokos Chris P. , Mamudu Lohuwa
Published: January 2022

To address the testing of the horrific pandemic disease that has terrified our global society, COVID-19, we have developed an analytical model that an individual can easily apply to determine if he or she tested positive or negative with a very high degree of accuracy. Our analytical model is real data-driven utilizing data obtained from the World Health Organization, WHO, and the United States Center for Disease Control and Prevention, CDC guidelines. Both WHO and CDC have identified several symptoms or risk factors from individuals diagnosed with the disease, COVID-19. They have identified and published nine symptoms that are associated with the disease, COVID-19. However, our structured analytical model identified only seven of the nine symptoms to statistically significantly contribute to the subject disease. They are fever, tiredness, dry cough, difficulty in breathing, sore throat, pain, and nasal congestion. Each of the symptoms shows highly likelihood of having COVID-19. Our analytical model was carefully developed, very well-validated, and statistically tested to achieve a 93% accuracy in the testing result. If a person is tested positive, we recommend that he/she seek medical evaluation and treatment. That is, once we receive the categorical data from a given individual, and we input into the proposed model, the output result will be the individual is tested positive or negative for COVID-19. The developed model identifies (estimated) the different weights of each of the seven symptoms or risk factors that play a major role in the decision process of the testing results. Our findings seek to enhance testing efficiency, treatment, control, and prevention strategy for the COVID-19 disease.
Avaliação de conteúdos educativos do YouTube® sobre prevenção da cárie dentária
Authors: Dalpoz Gabriel Quirino , Higasi Maura Sassahara , Uchida Tânia Harumi , Fujimaki Mitsue
Published: January 2022

Este estudo teve como objetivo avaliar a qualidade e a confiabilidade de vídeos de animação disponíveis no YouTube® sobre a prevenção da cárie dentária ao público infantil. Inicialmente, foi realizada uma busca no YouTube® utilizando expressões relacionadas ao tema: “Como cuidar dos dentes”, “Como escovar os dentes animação”, “Prevenção de cárie desenho”, “Como escovar os dentes criança”, “Como escovar os dentes desenho” e “Como escovar os dentes infantil”. Foram encontrados 132 vídeos, dos quais 84 não foram incluídos, por atenderem aos critérios de exclusão. Foram avaliados a qualidade e confiabilidade de 48 vídeos, por meio dos instrumentos DISCERN adaptado e JAMA. Os vídeos tiveram uma somatória de 165.459.240 visualizações no dia da coleta (=3.447.068). Os vídeos foram considerados de qualidade variável pelo DISCERN (=29,5; variando de 14 a 44) e de baixa confiabilidade pelo JAMA (=0,89; variando de 0,25 a 2). Conclui-se que os vídeos de animação de curta duração disponíveis no YouTube® sobre prevenção de cárie dentária para o público infantil, analisados neste estudo, foram considerados de qualidade variável e de baixa confiabilidade, necessitando de melhorias para promover uma orientação mais adequada ao grande público que os assiste.
Perfil farmacológico da prescrição de anti-hipertensivos e adequabilidade à diretriz brasileira de hipertensão
Authors: Silva Marcos Antonio Eleutério da , Pereira Thiago Lívio Barbosa , Pimenta Cláudia Jeane Lopes , Carmo Bruno Cleiton Macedo do , Carvalho Raphael da Rocha , Santos Sandrele Carla dos
Published: January 2022

O monitoramento contínuo da pressão arterial, associado a uma adequada prescrição medicamentosa a pacientes com hipertensão arterial sistêmica, mostram ser um desafio quando se trata de recomendações terapêuticas padronizadas no controle da hipertensão. O presente estudo teve como objetivo descrever o perfil farmacológico da utilização de anti-hipertensivos por pacientes de unidades de saúde e a adequabilidade das prescrições à diretriz brasileira de hipertensão. Trata-se de um estudo transversal, realizado a partir de dados secundários de prontuários de pacientes acompanhados pelo HIPERDIA. Os dados foram comparados com as recomendações de prescrição de anti-hipertensivos contidas na Diretriz Brasileira de Hipertensão Arterial, sendo descritas análises de frequências absoluta e relativa. Foi observado que diuréticos e inibidores da ECA representaram as classes medicamentosas mais prescritas. A prescrição de apenas um anti-hipertensivo foi mais prevalente entre aqueles pacientes com até 5 anos de diagnóstico de hipertensão. Divergências com as recomendações da diretriz foram observadas, principalmente, nas prescrições envolvendo dois ou mais medicamentos, representando um percentual de 16% destas.
Análise da energia eólica no Brasil usando Séries Temporais
Authors: Silva Mateus dos Santos , Santos Pedro Henrique Alves Bittencourt , Santos Ricardo Vitor Ribeiro dos , Nascimento Mateus do , Pascoa Marcelino Alves Rosa de , Pereira Renato Nunes , Oliveira Tiago Almeida de
Published: January 2022

O objetivo deste trabalho foi ajustar um modelo de séries temporais à série de energia elétrica gerada pela matriz eólica com a finalidade de estudar a presença de tendência, sazonalidade e realizar previsões. A série histórica utilizada consiste da produção de energia elétrica gerada pela matriz eólica, coletada mensalmente pelo Operador Nacional do Sistema Elétrico. A série está compreendida entre jan/2007 a mar/2021, com 171 observações. A série foi dividida em dois subconjuntos, ao primeiro (jan/2007 a dez/2019) foi designado o processo de modelagem (calibração) e ao segundo (jan/2020 a mar/2021) foi atribuído a avaliação das previsões (validação). O horizonte de previsão contemplou o período de abr/2021 a dez/2022. Realizou-se uma transformação Box-Cox na escala dos dados para tornar o modelo aditivo. Verificou-se a presença da componente de tendência. A partir dos correlogramas da FAC e FACP da série original transformada com uma diferença de ordem 1 foi possível propor alguns modelos. Buscaram-se modelos com resíduos não correlacionados e com menor AIC. Destes, realizaram-se previsões para o período de jan/2020 a mar/21 que foram comparadas com observações reais através do EQMP. O modelo SARIMA (5,1,2)×(0,0,3)12 foi escolhido, pois apresentou o menor EQMP. Observou-se que os meses subsequentes continuam seguindo o padrão crescente que ela vem mantendo desde de 2015. O modelo proposto para prever a quantidade de energia elétrica gerada pela matriz eólica de curto prazo vai permitir que os gestores tenham tempo suficiente para programar a operação de distribuição de energia de forma adequada.
O papel da enfermagem frente às mudanças sexuais no período do climatério
Authors: Andrade Ângela Roberta Lessa de , Pontes Alice Fonseca , Silva Sara Rodrigues Cordeiro da , Silva Beatriz Caetano da , Deodoro Mirela Ferreira Pessoa , Costa Aurélio Molina da
Published: January 2022

Objetivo: Este estudo surgiu devido a necessidade de avaliar o conhecimento sobre sexualidade no climatério entre os enfermeiros da Estratégia Saúde da Família. Método: Pesquisa de campo, com abordagem quantitativa, de cunho descritivo e de corte transversal. A coleta foi realizada no período de Junho à Julho de 2015. Resultados: Para a avaliação do questionário foram consultados 13 profissionais para avaliar o questionário que trata sobre sexualidade humana. Em termos gerais, apenas um dos experts consideraram o questionário razoável.   Sendo desta forma o questionário aprovado pela etapa dos experts. Foi aplicado ainda o coeficiente de confiabilidade de alfa de Cronbach obtendo resultado igual a 0,86. O que indica sua confiabilidade nas respostas dos experts. Considerações finais: Existe a necessidade de transversalidade do cuidado de enfermagem à mulher no climatério desde o tratar do cuidado do corpo com propriedade e intimidade com o mesmo, seus aspectos mais elementares do cuidado com a higiene corporal até aqueles tecnicamente mais complexos, como identificar inadequações e disfunções sexuais prescrevendo os cuidados de enfermagem.
BIMBINGAN TEKNIK PENYUSUNAN STANDAR OPERASIONAL PROSEDUR PENYELENGGARAN REKAM MEDIS DI PUSKESMAS MONDOKAN KABUPATEN SRAGEN
Authors: Sugiarsi Sri , Antik Pujihastuti  , Trismianto Asmo Sutrisno
Published: January 2022

Puskesmas Mondokan Kabuapaten Sragen sudah mempunyai sebagian kecil Standar Operasional Prosedur(SOP) terkait penyelenggaraan rekam medis. Namun SOP tersebut belum bisa diterapkan secara optimal karena dinilai tidak efisien. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pemahaman dan kemampuan pegawai puskesmas dalam menyusunan SOP penyelenggaraan rekam medis. Pelaksanaan kegiatan Pengabdian Pada Masyarakat ini dikemas dengan menggunakan pendekatan workshop. Kegiatan yang dilakukan menggunakan metode ceramah, aplikasi, diskusi dan latihan. Pelaksanaan pengabdian masyarakat berhasil karena adanya kesesuaian materi dengan kebutuhan petugas pegawai puskesmas untuk meningkatkan kemampuannya dalam menyusun SOP, respon yang positif dari pegawai puskesmas dan sebagaian besar memahami dan mampu menyusun SOP.
UPAYA PENCEGAHAN STUNTING MELALUI PELATIHAN KADER KESEHATAN DI DESA GERBOSARI KABUPATEN KULON PROGO
Authors: Nuryati  , Santoso Dian Budi , Pramono Angga Eko
Published: January 2022

Stunting merupakan salah satu masalah kesehatan masyarakat yang menjadi prioritas pemerintah di bidang kesehatan. Hasil Riset Kesehatan Dasar (Riskesdas) 2018 menunjukkan bahwa kejadian stunting (pendek dan sangat pendek) di Indonesia sebanyak 30,8% (11,5% sangat pendek dan 19,3% pendek) dan tahun 2019 menjadi sekitar 27%, angka ini mengalami penurunan dari tahun 2013 dimana terdapat 37,2% balita stunting (18% sangat pendek dan 19,2% pendek). Namun angka tersebut masih jauh dari target nasional dan WHO yaitu dibawah 20%. Berdasarkan hasil analisis masalah bidang kesehatan di Desa Gerbosari ditemukan bahwa prevalensi stunting pada balita cukup tinggi dan pemahaman masyarakat terhadap stunting juga masih kurang. Oleh karena itu perlu dilakukan upaya pencegahan stunting pada balita melalui pelatihan kader kesehatan di Desa Gerbosari. Kegiatan kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan pemahaman kader kesehatan mengenai stunting pada balita dan upaya pencegahannya. Kegiatan pelatihan dilaksanakan di Balai Desa Gerbosari secara bertahap untuk 105 kader kesehatan yang terbagi ke dalam 16 Posyandu. Kegiatan dilakukan dengan metode sosialisasi yang mencakup penyampaian materi, pemutaran video, dan diskusi. Capaian kegiatan pelatihan diukur menggunakan kuesioner evaluasi kegiaatan yang diisi oleh semua kader kesehatan di Desa Gerbosari, Kabupaten Kulon Progo. Dari hasil evaluasi diketahui bahwa mayoritas kader kesehatan telah memahami berbagai mitos dan fakta tentang stunting serta upaya pencegahannya.
BIMBINGAN TEKNIS PERAMALAN JUMLAH KUNJUNGAN PASIEN DENGAN TABLEAU
Authors: Nurmalasari Mieke , Zuama Qomarania Witri , Anggita Temesvari Nauri , Saras Pertiwi Tria
Published: January 2022

ABSTRAK.  Peramalan jumlah kunjungan pasien berguna untuk membantu manajemen dalam membuat kebijakan dan perencanaan yang efektif dan efisien. Pesatnya perkembangan teknologi menjadikan data kesehatan digital sebagai salah satu sumber big data. Perlu dilakukan peningkatan pengetahuan pada mahasiswa dan tenaga Perekan Medis dan Manajemen Informasi Kesehatan dalam menganalisis data kunjungan pasien. Metode yang digunakan dalam kegiatan ini adalah pelatihan atau bimbingan teknis yang bersifat teoritis dan praktis. Hasil dari pelatihan ini adalah peningkatan pengetahuan peserta dalam menganalisis data peramalan kunjungan pasien menggunakan software statistik A Tableau.

Kata kunci: kunjungan pasien; peramalan; analisis data; public tableau

ABSTRACT. Forecasting number of visits is useful to help management to make effective and efficient policies and plans. The rapid development of technology makes digital health data as a one of big data sources. It is necessary to increase the knowledge of student and Professional Health Information Management in analyzing the patient visit data. The method used in this activity is a training or technical guidance which is namely theoretical and practical. The result of this training is an increase in participants' knowledge in analyzing the forecasting of patient visit data using a statistical software Tableau.

Keywords: patient visit; forecasting; data analytics; public tableau
Fuel Planning Errors in General Aviation from 2015 to 2020
Authors: Kalagher Hilary
Published: January 2022

BACKGROUND: Planning, whether preflight or in-flight, is a cause of accident that is presumably almost entirely preventable. Planning skills on the part of the pilot should assist in avoiding dangerous situations with regards to light conditions, weather, fuel shortage, and/or
improper weight and balance. Fuel planning is noted as especially unnecessary, as fuel planning is not considered a complex skill but part of proper flight preparation and in-flight planning.METHODS: A total of 196 accident reports from 2015 until 2020 were extracted from the NTSB
online database in which the probable cause included either preflight or in-flight planning as a cause attributed to the pilot. Of those accidents, the majority (N = 131, 67%) were attributed to fuel planning and were further analyzed.RESULTS: Fuel-planning related accidents
were significantly less often fatal compared to all planning-related accidents and all fuel-related accidents. The majority of fuel planning accidents resulted in fuel exhaustion. Additionally, the cause attributed to the accidents was frequently the skill-based error of “fuel planning
(pilot)” and the crew resource management issue of “fuel-fluid level”. Specific information regarding the pilot’s fuel plan was only available in 52 (40%) of the accident reports.CONCLUSIONS: The frequency of fuel-related planning accidents suggests that
this aspect of pilotage is underestimated and requires more attention both in training and in standard operating procedures. In particular, more detailed information regarding the pilot’s fuel plan is necessary in order to determine which step in the process most frequently results in
an accident.Kalagher H. Fuel planning errors in general aviation from 2015 to 2020. Aerosp Med Hum Perform. 2021; 92(12):970–974.
CARACTERIZACIÓN CLÍNICO EPIDEMIOLÓGICA DEL SOBREPESO Y LA OBESIDAD EN LA PARROQUIA RURAL SAN GERARDO, CHIMBORAZO, ECUADOR
Authors:   Universidad Nacional de Chimborazo, Solis Cartas Urbano ,   Escuela Superior Politécnica de Chimborazo, Valdés Gonzaléz Elda María ,   Universidad Nacional de Chimborazo, Abad Urgiles Karolina Estefania ,   Ministerio Salud Pública del Ecuador, Soria Granizo Fernanda Yomira ,   Ministerio Salud Pública del Ecuador, Valdés González Jorge Luis ,   Escuela Superior Politécnica de Chimborazo
Published: January 2022

Los trastornos nutricionales por exceso constituyen factores de riesgo para múltiples enfermedades crónicas. Su conocimiento puede ser utilizado como predictor de aparición o de complicaciones de las mismas. El objetivo de la presente investigación fue caracterizar desde el punto de vista clínico epidemiológico el sobrepeso y la obesidad en los adultos de la parroquia rural San Gerardo de la provincia Chimborazo. Para esto se desarrolló una investigación básica, no experimental, con diseño descriptivo que tuvo como universo un total de 414 personas y la muestra quedó conformada por 213 adultos con sobrepeso u obesidad. Se aplicó un cuestionario para obtener la información necesaria en relación a las variables identificadas para el estudio. Los principales resultados incluyen promedio de edad de 44,23 años y predominio de féminas (60,56%). El 41,78% de las personas reportó al menos una enfermedad, donde la hipertensión arterial (50,56%), el hipotiroidismo (23,60%) y la diabetes mellitus (17,98%) fueron las más representadas; el 69,65% de las personas presentó sobrepeso y el 30,05% obesidad. El 70,89% de las personas presentó un nivel bajo de conocimiento sobre prevención del sobrepeso y la obesidad. Se concluye que existe un elevado porcentaje de población adulta en la parroquia rural San Gerardo con trastornos nutricionales por exceso; lo que incrementa el riesgo de padecer enfermedades crónicas. Los resultados obtenidos en torno al nivel de conocimiento sobre prevención del sobrepeso y la obesidad muestran la necesidad de implementar acciones educativas encaminadas a mejorar el conocimiento de la población sobre temas fundamentales de salud.
BANTUAN TEKNIS PELAKSANAAN PENGECATAN BALAI RW XI JALAN SILIKAT KELURAHAN PURWANTORO KECAMATAN BLIMBING KOTAMADYA MALANG
Authors: Subagyo Udi , Raharjo Nain Dhaniarti , M.Kurniawan R, Achendri , Khamim Moch. , Raharjo Boby Asukmajaya
Published: January 2022

Balai RW is a construction or building used by residents for RT activities or activities of local residents and has been built since 1998 and is used as a place for local residents' activities. For the condition of the Balai RW XI in 2020 today, there are many that are not suitable for use, especially in wall construction, where many conditions are damp and the wall paint is peeling off so that repairs are needed in the form of painting the outer and inner walls. Implementation of Community Service Painting of Balai RW XI Jl. Silikat Kel.. Purwantoro Kec. Blimbing Malang city is carried out are: 1. Calculation of the Budget Plan for Painting Implementation Costs Balai RW XI is Rp. 13,955,000, - (Thirteen Million Nine Hundred Fifty Five Thousand Rupiah) the source of funds from PKM Polinema activities and RW XI Cash. 2. Painting the Balai RW XI is prioritized on repairing inner and outer wall paints. 3. Implementation of painting at Balai RW XI will be carried out from 20 July 2020 - 8 August 2020 with a total processing time of 3 weeks.
Recent Applications of Carbon Nanotubes in Organic Solar Cells
Authors: Muchuweni Edigar , Mombeshora Edwin T. , Martincigh Bice S. , Nyamori Vincent O.
Published: January 2022

In recent years, carbon-based materials, particularly carbon nanotubes (CNTs), have gained intensive research attention in the fabrication of organic solar cells (OSCs) due to their outstanding physicochemical properties, low-cost, environmental friendliness and the natural abundance of carbon. In this regard, the low sheet resistance and high optical transmittance of CNTs enables their application as alternative anodes to the widely used indium tin oxide (ITO), which is toxic, expensive and scarce. Also, the synergy between the large specific surface area and high electrical conductivity of CNTs provides both large donor-acceptor interfaces and conductive interpenetrating networks for exciton dissociation and charge carrier transport. Furthermore, the facile tunability of the energy levels of CNTs provides proper energy level alignment between the active layer and electrodes for effective extraction and transportation of charge carriers. In addition, the hydrophobic nature and high thermal conductivity of CNTs enables them to form protective layers that improve the moisture and thermal stability of OSCs, thereby prolonging the devices’ lifetime. Recently, the introduction of CNTs into OSCs produced a substantial increase in efficiency from ∼0.68 to above 14.00%. Thus, further optimization of the optoelectronic properties of CNTs can conceivably help OSCs to compete with silicon solar cells that have been commercialized. Therefore, this study presents the recent breakthroughs in efficiency and stability of OSCs, achieved mainly over 2018–2021 by incorporating CNTs into electrodes, active layers and charge transport layers. The challenges, advantages and recommendations for the fabrication of low-cost, highly efficient and sustainable next-generation OSCs are also discussed, to open up avenues for commercialization.
The Influence of Climate Conditions and On-Skin Positioning on InGaZnO Thin-Film Transistor Performance
Authors: Catania Federica , Oliveira Hugo De Souza , Costa Angeli Martina A. , Ciocca Manuela , Pané Salvador , Münzenrieder Niko , Cantarella Giuseppe
Published: January 2022

Thin-film transistors (TFTs) based on amorphous indium-gallium-zinc-oxide (a-IGZO) have proved promising features for flexible and lightweight electronics. To achieve technological maturity for commercial and industrial applications, their stability under extreme environmental conditions is highly required. The combined effects of temperature (T) from −30.0°C to 50.0°C and relative humidity (RH) stress from 0 to 95% on a-IGZO TFT is presented. The TFT performances and the parameters variation were analysed in two different experiments. First, the TFT response was extracted while undergoing the most extreme climate conditions on Earth, ranging from the African Desert (50.0°C, 22%) to Antarctic (−30.0°C, 0%). Afterwards, the device functionality was demonstrated in three parts of the human body (forehand, arm and foot) at low (35%), medium (60%) and high (95%) relative humidity for on-skin and wearable applications. The sensitivity to T/RH variations suggests the suitability of these TFTs as sensing element for epidermal electronics and artificial skin.
Genetic Variants and Their Associations to Type 2 Diabetes Mellitus Complications in the United Arab Emirates
Authors: ElHajj Chehadeh Sarah , Sayed Noura S. , Abdelsamad Hanin S. , Almahmeed Wael , Khandoker Ahsan H. , Jelinek Herbert F. , Alsafar Habiba S.
Published: January 2022

Aim

Type 2 Diabetes Mellitus (T2DM) is associated with microvascular complications, including diabetic retinopathy (DR), diabetic nephropathy (DNp), and diabetic peripheral neuropathy (DPN). In this study, we investigated genetic variations and Single Nucleotide Polymorphisms (SNPs) associated with DR, DNp, DPN and their combinations among T2DM patients of Arab origin from the United Arab Emirates, to establish the role of genes in the progression of microvascular diabetes complications.

Methods

A total of 158 Emirati patients with T2DM were recruited in this study. The study population was divided into 8 groups based on the presence of single, dual, or all three complications. SNPs were selected for association analyses through a search of publicly available databases, specifically genome-wide association study (GWAS) catalog, infinome genome interpretation platform, and GWAS Central database. A multivariate logistic regression analysis and association test were performed to evaluate the association between 83 SNPs and DR, DNp, DPN, and their combinations.

Results

Eighty-three SNPs were identified as being associated with T2DM and 18 SNPs had significant associations to one or more diabetes complications. The most strongly significant association for DR was rs3024997 SNP in the VEGFA gene. The top-ranked SNP for DPN was rs4496877 in the NOS3 gene. A trend towards association was detected at rs833068 and rs3024998 in the VEGFA gene with DR and rs743507 and rs1808593 in the NOS3 gene with DNp. For dual complications, the rs833061, rs833068 and rs3024997 in the VEGFA gene and the rs4149263 SNP in the ABCA1 gene were also with borderline association with DR/DNp and DPN/DNp, respectively. Diabetic with all of the complications was significantly associated with rs2230806 in the ABCA1 gene. In addition, the highly associated SNPs rs3024997 of the VEGFA gene and rs4496877 of the NOS3 gene were linked to DR and DPN after adjusting for the effects of other associated markers, respectively.

Conclusions

The present study reports associations of different genetic polymorphisms with microvascular complications and their combinations in Emirati T2DM patients, reporting new associations, and corroborating previous findings. Of interest is that some SNPs/genes were only present if multiple comorbidities were present and not associated with any single complication.
Islets Transplantation at a Crossroads - Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the American Diabetes Association Congress
Authors: Witkowski Piotr , Philipson Louis H. , Buse John B. , Robertson R. Paul , Alejandro Rodolfo , Bellin Melena D. , Kandeel Fouad , Baidal David , Gaglia Jason L. , Posselt Andrew M. , Anteby Roi , Bachul Piotr J. , Al-Salmay Yaser , Jayant Kumar , Perez-Gutierrez Angelica , Barth Rolf N. , Fung John J. , Ricordi Camillo
Published: January 2022

Clinical islet allotransplantation has been successfully regulated as tissue/organ for transplantation in number of countries and is recognized as a safe and efficacious therapy for selected patients with type 1 diabetes mellitus. However, in the United States, the FDA considers pancreatic islets as a biologic drug, and islet transplantation has not yet shifted from the experimental to the clinical arena for last 20 years. In order to transplant islets, the FDA requires a valid Biological License Application (BLA) in place. The BLA process is costly and lengthy. However, despite the application of drug manufacturing technology and regulations, the final islet product sterility and potency cannot be confirmed, even when islets meet all the predetermined release criteria. Therefore, further regulation of islets as drugs is obsolete and will continue to hinder clinical application of islet transplantation in the US. The Organ Procurement and Transplantation Network together with the United Network for Organ Sharing have developed separately from the FDA and BLA regulatory framework for human organs under the Human Resources & Services Administration to assure safety and efficacy of transplantation. Based on similar biologic characteristics of islets and human organs, we propose inclusion of islets into the existing regulatory framework for organs for transplantation, along with continued FDA oversight for islet processing, as it is for other cell/tissue products exempt from BLA. This approach would reassure islet quality, efficacy and access for Americans with diabetes to this effective procedure.
Finite-Element Modelling of Double-Roller Clamping Spinning of Wind Concentrator
Authors: Qu Xueyong , Xu Hongzhong , Fan Shuqin , Cheng Xiaole , Zhao Shengdun , Hua Yi
Published: January 2022

In order to improve the unit-power of a wind-driven generator, a wind concentrator with complex shape is installed in front of the impeller, which makes the airflow integrated and accelerated. It is important to manufacture the wind concentrator with high precision. The double-roller clamping spinning (DRCS) is a dieless, flexible spinning process that is very suitable for forming a wind concentrator with complex shape. The profile of a wind concentrator is divided into two parts: the contraction section and the expanding section. The process routes of both the contraction section and the expanding section are determined, and roller path equations are derived. Then the finite element (FE) analysis model that can describe the plastic deformation behavior of the DRCS forming for a wind concentrator is established, and the DRCS process of the flange is simulated. Furthermore, the wall-thickness distribution on the expanding section during the forming process is obtained. Finally, the reliability of the FE model is verified using the experimental results.
Chronic Background Radiation Correlates With Sperm Swimming Endurance in Bank Voles From Chernobyl
Authors: Kivisaari Kati , Calhim Sara , Lehmann Philipp , Boratyński Zbyszek , Mousseau Timothy A. , Møller Anders P. , Mappes Tapio
Published: January 2022

Sperm quantity and quality are key features explaining intra- and interspecific variation in male reproductive success. Spermatogenesis is sensitive to ionizing radiation and laboratory studies investigating acute effects of ionizing radiation have indeed found negative effects of radiation on sperm quantity and quality. In nature, levels of natural background radiation vary dramatically, and chronic effects of low-level background radiation exposure on spermatogenesis are poorly understood. The Chernobyl region offers a unique research opportunity for investigating effects of chronic low-level ionizing radiation on reproductive properties of wild organisms. We captured male bank voles (Myodes glareolus) from 24 locations in the Chernobyl exclusion zone in 2011 and 2015 and collected information on sperm morphology and kinetics. The dataset is limited in size and there overall was a relatively weak correlation between background radiation and sperm quality. Still, some correlations are worth discussing. First, mid-piece segments of spermatozoa tended to be smaller in bank vole males from areas with elevated background radiation levels. Second, we demonstrated a significant positive relationship between background radiation dose rates and the proportion of static spermatozoa among males within and among study locations after 10 as well as 60 min of incubation. Our results provide novel evidence of damaging effects of low dose ionizing radiation on sperm performance in wild rodent populations, and highlight that this topic requires further study across the natural gradients of background radiation that exist in nature.
Dynamics of Macrophage, T and B Cell Infiltration Within Pulmonary Granulomas Induced by Mycobacterium tuberculosis in Two Non-Human Primate Models of Aerosol Infection
Authors: Hunter Laura , Hingley-Wilson Suzie , Stewart Graham R. , Sharpe Sally A. , Salguero Francisco Javier
Published: January 2022

Non-human primate models of Tuberculosis (TB) are one of the most commonly used within the experimental TB field because they closely mimic the whole spectrum of disease progression of human TB. However, the early cellular interactions of the pulmonary granuloma are still not well understood. The use of this model allows investigation into the early interactions of cells within pulmonary granulomas which cannot be undertaken in human samples. Pulmonary granulomas from rhesus and cynomolgus macaques from two timepoints post infection were categorised into categories 1 – 6 (early to late stage granulomas) and immunohistochemistry was used to identify CD68+ macrophages, CD3+ T cells and CD20+ B cells. Multinucleated giant cells and acid-fast bacilli were also quantified. At week four post infection, cynomolgus macaques were found to have more CD68+ cells than rhesus in all but category 1 granulomas. Cynomolgus also had a significantly higher percentage of CD20+ B cells in category 1 granulomas. At week twelve post infection, CD68+ cells were most abundant in category 4 and 5 granulomas in both species; however, there were no significant differences between them. CD3+ T cells and CD20+ B cells were significantly higher in the majority of granuloma categories in cynomolgus compared to rhesus. Multinucleated giant cells and acid-fast bacilli were most abundant in categories 5 and 6 at week 12 post challenge in both species. This study has identified the basic cellular composition and spatial distribution of immune cells within pulmonary granulomas in both rhesus and cynomolgus macaques over time. The data from this study will add to the knowledge already gained in this field and may inform future research on vaccines and therapeutics for TB.