bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the roles of HIV co-infection and socio-demographic factors as determinants of Quality of Life among Nigerians with Tuberculosis
Authors: Olagunju Peter J , Odukoya Olukemi O , Olagunju Andrew T , Balogun Mobolanle R
Published: January 2018

Background: Tuberculosis [TB] remains a major global public health problem, and particularly in resource-restricted settings with disproportionately high burden. This study is aimed at assessing quality of life [QoL] and the roles of HIV co-infection along with socio-demographic factors on QoL among subjects with TB.Methodology: This is a multi-center cross-sectional study among 440 participants recruited by multi-stage sampling technique across 40 Directly Observed Treatment Short-course [DOTS] centres. Interviews were done using designed questionnaire to collect information on socio-demographic and clinical details of respondents. Subsequently, the World Health Organization Quality of Life-BREF [WHOQOL-BREF] questionnaire was used to evaluate QoL.Results: Most (61.1%) of the participants was aged between 21 and 40 years, 61.6% were married and 74.5% had a paid job. Majority of the subjects reported fair QoL across all domains. Employment status and monthly income were significantly associated with participants overall QoL and their satisfaction with health (p<0.05). Also, age, gender, marital status, ethnicity and educational status were significantly associated with the social domain of QoL. The HIV co-infection was found to be significantly associated with the physical aspect of their QoL (p<0.05).Conclusion: Optimal treatment of HIV co-infection and incorporation of psychosocial medicine into TB management are indicated for improved QoL. Similarly, routine assessment of QoL is desirable.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.21-29
A Study of Nurses’ Perception of Professional Values in the University Hospitals Affiliated with Jahrom University of Medical Sciences, 2015
Authors: Jahromi Marzieh Kargar , Koshkaki Afifeh Rahmanian , Poorgholami Farzad , Talebizadeh Malihe
Published: January 2018

Objectives: In order to deal with professional ethical issues successfully, nurses and other providers of clinical care need to rely on professional values that are meant to guide their professional decision-making, actions and behaviors .These values form the basis of nursing. Accordingly, the present study aims to investigate nurses’ perception of professional values in the hospitals affiliated with Jahrom University of Medical Sciences.Method: In this descriptiveanalytical study, 100 nurses employed at the university hospitals of Jahrom were selected through simple convenience sampling. To examine the subjects’ perception of professional values, the researchers used a two-part questionnaire: part one consisted of questions about the personal and social characteristics of the subjects; part two was the Nurses Professional Values Scale-Revised. The latter consists of 26 items based on American Nurses Association Code of Ethics for Nurses and addresses the following areas: caring (9 items), activism (5 items), trust (5 items), professionalism (4 items) and justice (3 items).Answers are scored based on a 5-point Likert scale: the answer choices “Not important” and “Very important” are assigned 1 point and 5 points respectively. The score range is between 26 and 130—higher scores indicate the respondent’s greater familiarity with professional values.Findings: The participants of the study consisted of 99 nurses who were selected from the various parts of the university hospitals of Jahrom. The participants’ mean scores for caring, activism, trust, professionalism, justice and total perception of professional values were found to be 32.15,15.47, 17.37, 13.32,10.66 and 88.98 respectively. The results of the study showed that there was not a significant relationship between the age, gender and marital status of nurses on one hand and their professional values scores on the other (P=0.7).Conclusion: There is need for effective programs to enhance nurses’ awareness of certain of their professional duties and improve their professional performance in a wide range of professional areas alongside their duties as care-givers.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.47-51
Association of APOB 3ʹ-VNTR alleles with type 2 diabetes, BMI, systolic and diastolic blood pressure
Authors: Sajib Abu Ashfaqur , Khan Mohammad Abu Taher , Haque Mohammad Nasimul , Kibria KM Kaderi , Chowdhury Abul Kalam Azad , Yeasmin Sabina
Published: January 2018

Background: Apolipoprotein B (APOB) is a component of chylomicrons, low-density lipoproteins (LDL), very low-density lipoproteins (VLDL), intermediate density lipoproteins (IDL) and functions as the main protein for transporting cholesterol to peripheral cells. APOB gene has an AT-rich VNTR site at its 3ʹ-untranslated region (3ʹ-UTR). APOB 3ʹ-VNTR alleles with ≥36 repeats have been shown to be strongly associated with increased serum lipid levels, gallstone formation and coronary artery disease.Objectives: To investigate any possible association of APOB 3ʹ-VNTR alleles with type 2 diabetes, BMI, systolic and diastolic blood pressure.Materials and methods: APOB 3ʹ-VNTR region in the DNA of non-diabetic controls and type 2 diabetic patients were amplified by polymerase chain reaction (PCR) and the numbers of core repeat in the amplified products were determined. Frequencies of the APOB alleles and genotypes among the controls and the patients were calculated and statistical analyses were performed.Results and discussion: Here we report for the first time that APOB 3ʹ-VNTR alleles have different distribution frequencies among type 2 diabetic and non-diabetic individuals. We also observed higher body mass index (BMI), systolic and diastolic blood pressures in individuals who had at least one APOB 3ʹ-VNTR allele with ≥35 repeats.Conclusion: Our study might bridge among the genetic signature of APOB 3ʹ-VNTR, high APOB protein level in blood, diabetes and other co-morbidities.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.71-77
Phytochemical and antibacterial screening of different fractions of root part of Ipomea Turpethum
Authors: Sohail Tehmina , Ferheen Sadia , Imran Hina , Yaqeen Zahra , Rehman Atiq Ur , Khan Rashid Ali
Published: January 2018

Objective: In folk medicines, different herbs and plants have been used for many thousands of years .Now it is important to investigate these plants and herbs scientifically which have been used in traditional medicines. The aim of this study was to investigate the antibacterial activity and preliminary phytochemical screening of root of Ipomea turpethum extracted in methanol and its fractions.Methods: The methanol extract was further extracted with three solvents ethyl acetate, chloroform and hexane and analyzed for their antibacterial activity using by agar well diffusion method. They were tested against six bacteria; Echrichia coli, Staphylococcus aureus, Staphylococcus epidermidus, Proteus vulgaris, Pseudomonas auroginosa and Salmonella typhi. The susceptibility of microorganisms to all three fractions was compared with each other and with standard antibotic (Ampicillin). The fractions of Ipomea turpethum was also qualitatively analyzed for the presence of chemical components, i.e. saponins, alkaloids, flavonoids, tannins and glycosides.Result: Among all fractions methanol exhibited highest antibacterial activity (average zone of inhibition 23.53mm ± 1.3) while ethyl acetate exhibited least antibacterial activity (average zone of inhibition 18.50mm ± 3.5). Minimum inhibitory concentration of methanol, ethyl acetate, chloroform and hexane fractions was found in the range of 650ug/ml to 2500ugl/ml against microorganisms.Conclusion: Results obtained from this preliminary in-vitro experiment indicate that, all three fractions of Ipomea turpethum has good antibacterial activity against all microorganisms used. By phytochemical analysis of extract, it has been found to contain some nutrient and chemical components which support its ethenomedicinal use but further work is required for development of new antibiotic compounds.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.93-97
Honey potentially mitigates morphine analgesic tolerance and physical dependence in rats
Authors: Hashim Siti Norhajah , Mohamad Nasir , Mustapha Zulkifli , Bakar Nor Hidayah Abu , Husain Rohayah , Mat Khairi Che , Zakaria Nur Husna , Mohd Adnan Liyana Hazwani , Shariff Halim , UlulIlmie Mohd
Published: January 2018

Introduction:Honey has been used traditionally in medicine as well as food supplements. Honeybees are said to be able to cure many diseases. However, its influences on opioid tolerance and dependence have not yet been clarified.Materials and Methods:Adult male Sprague- Dawley rats were rendered tolerant to the analgesic effect of morphine by injection of morphine (10 mg/kg, i.p.) twice daily for 14 days. To develop morphine dependence rats given escalating doses of chronic morphine. To determine the effect of stingless bee honey on the development of morphine tolerance and dependence. The hotplate and naloxone precipitation tests were used to assess the degree of tolerance and dependence, respectively.The results: Our results showed that chronic morphine-injected rats displayed tolerance to the analgesic effect of morphine as well as morphine dependence. Methadone+morphine (MetM), methadone+morphine+ honey (MetMH) and morphine+Honey (MH) significantlylower the development of morphine tolerance with p-value p<0.05. In addition, concomitant treatment of morphine with MH and MetMH attenuated almost all of the naloxone-induced withdrawal signs which include abdominal contraction, diarrhea, pertussis, teeth chattering, and jumping.Conclusion: The data indicate that honey has a potential to reduce tolerant and dependence property.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.138-143
A Case Report of Atlanto-occipital Assimilation
Authors: Shetty Ashwini S , Jetti Raghu , Sirasanagandla Srinivasa Rao , Nelluri Venumadhav
Published: January 2018

Background: Congenital fusion of atlas to the basiocciput is defined as atlanto-occipital assimilation/occipitalization of atlas.Case report: During the norma basalis demonstration session of skull, we have noticed an assimilation/occipitalization of atlas vertebra. Atlas fusion may be complete or partial; assimilation of atlas is associated with neurovascular and skeletal anomalies.Conclusion: Atlanto-occipital fusion may reduce the dimensions of foramen magnum thereby leads to brain stem compression causing the consequent neurological complications. Present case may pose difficulty in performing cisternal puncture. This anomaly has high clinical significance as it mimics the Arnold Chiari malformation.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.169-171
The challenges of technology-based self-care in chronic diseases: An issue deserving further attention
Authors: Sharifi Hassan , Zeydi Amir Emami
Published: January 2018

Abstract not availableBangladesh Journal of Medical Science Vol.17(1) 2018 p.178-179
The Preparation and Properties of Fluoroacrylate-Modified Polysiloxane as a Fabric Coating Agent
Authors: Jin Hua , Xu Wei
Published: January 2018

Polysiloxanes, which can add high softness and lubricity to treated textiles, have been proposed as softening post-finishing agents for fabric. However, the hydrophobicity of the finished fabric is not satisfactory. In this work, long-chain fluoroalkyl acrylate was used to modify the polysiloxane, aimed at improving hydrophobicity of the finished fabric and retaining its softness simultaneously. Fourier transform infrared spectroscopy (FT-IR), nuclear magnetic resonance spectra (1H/13C NMR), and thermogravimetric analysis (TGA) were used to characterize the chemical structure and thermal stability of the as-prepared polymer. The modified polysiloxane was tested as a finishing agent. Its film morphologies on the fabric surface and on a silicon wafer were determined. Chemical compositions and performance properties of the finished fabric were investigated. By bonding long-chain fluoroalkyl, the modified polysiloxane presented good thermal stability. Due to the combined effect of the low surface free energy of the perfluorinated side chains and the relatively high surface roughness of the cotton fibers, the treated fabric had favorable hydrophobicity with a WCA of 144.7° on its surface. In addition, their softness was increased, but the color remained unchanged.
Fractional Time Fluctuations in Viscoelasticity: A Comparative Study of Correlations and Elastic Moduli
Authors: Rodríguez Rosalío , Salinas-Rodríguez Elizabeth , Fujioka Jorge
Published: January 2018

We calculate the transverse velocity fluctuations correlation function of a linear and homogeneous viscoelastic liquid by using a generalized Langevin equation (GLE) approach. We consider a long-ranged (power-law) viscoelastic memory and a noise with a long-range (power-law) auto-correlation. We first evaluate the transverse velocity fluctuations correlation function for conventional time derivatives C ^ N F ( k → , t ) and then introduce time fractional derivatives in their equations of motion and calculate the corresponding fractional correlation function. We find that the magnitude of the fractional correlation C ^ F ( k → , t ) is always lower than the non-fractional one and decays more rapidly. The relationship between the fractional loss modulus G F ″ ( ω ) and C ^ F ( k → , t ) is also calculated analytically. The difference between the values of G ″ ( ω ) for two specific viscoelastic fluids is quantified. Our model calculation shows that the fractional effects on this measurable quantity may be three times as large as compared with its non-fractional value. The fact that the dynamic shear modulus is related to the light scattering spectrum suggests that the measurement of this property might be used as a suitable test to assess the effects of temporal fractional derivatives on a measurable property. Finally, we summarize the main results of our approach and emphasize that the eventual validity of our model calculations can only come from experimentation.
Asymmetric Conjugate Addition of α,α-Disubstituted Aldehydes to Nitroalkenes Organocatalyzed by Chiral Monosalicylamides from trans-Cyclohexane-1,2-Diamines
Authors: Martínez-Guillén José , Flores-Ferrándiz Jesús , Gómez Cecilia , Gómez-Bengoa Enrique , Chinchilla Rafael
Published: January 2018

Primary amine-salicylamides derived from chiral trans-cyclohexane-1,2-diamines are used as organocatalysts for the enantioselective conjugate addition of α,α-disubstituted aldehydes to arylated and heteroarylated nitroalkenes. The reaction is performed in the presence of 4-dimethylaminopyridine as an additive in dichloromethane as a solvent at room temperature. The corresponding enantioenriched γ-nitroaldehydes are obtained with enantioselectivities up to 95%. Theoretical calculations are used to justify the reasons of the stereoinduction.
Immobilization of Enzymes on a Phospholipid Bionically Modified Polysulfone Gradient-Pore Membrane for the Enhanced Performance of Enzymatic Membrane Bioreactors
Authors: Guo Yizong , Zhu Xueyan , Fang Fei , Hong Xiao , Wu Huimin , Chen Dajing , Huang Xiaojun
Published: January 2018

Enzymatic membrane bioreactors (EMBRs), with synergistic catalysis-separation performance, have increasingly been used for practical applications. Generally, the membrane properties, particularly the pore structures and interface interactions, have a significant impact on the catalytic efficiency of the EMBR. Therefore, a biomimetic interface based on a phospholipid assembled onto a polysulfone hollow-fiber membrane with perfect radial gradient pores (RGM-PSF) has been prepared in this work to construct a highly efficient and stable EMBR. On account of the special pore structure of the RGM-PSF with the apertures decreasing gradually from the inner side to the outer side, the enzyme molecules could be evenly distributed on the three-dimensional skeleton of the membrane. In addition, the supported phospholipid layer in the membrane, prepared by physical adsorption, was used for the immobilization of the enzymes, which provides sufficient linkage to prevent the enzymes from leaching but also accommodates as many enzyme molecules as possible to retain high bioactivity. The properties of the EMBR were studied by using lipase from Candida rugosa for the hydrolysis of glycerol triacetate as a model. Energy-dispersive X-ray and circular dichroism spectroscopy were employed to observe the effect of lecithin on the membrane and structure changes in the enzyme, respectively. The operational conditions were investigated to optimize the performance of the EMBR by testing substrate concentrations from 0.05 to 0.25 M, membrane fluxes from 25.5 to 350.0 L·m−2·h−1, and temperatures from 15 to 55 °C. As a result, the obtained EMBR showed a desirable performance with 42% improved enzymatic activity and 78% improved catalytic efficiency relative to the unmodified membrane.
Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents
Authors: Zafar Ayesha , Pilkington Lisa , Haverkate Natalie , Van Rensburg Michelle , Leung Euphemia , Kumara Sisira , Denny William , Barker David , Alsuraifi Ali , Hoskins Clare , Reynisson Jóhannes
Published: January 2018

It is now established that the thieno[2,3-b]pyridines are a potent class of antiproliferatives. One of the main issues encountered for their clinical application is their low water solubility. In order to improve this, two strategies were pursued. First, a morpholine moiety was tethered to the molecular scaffold by substituting the sulphur atom with nitrogen, resulting in a 1H-pyrrolo[2,3-b]pyridine core structure. The water solubility was increased by three orders of magnitude, from 1.2 µg/mL (1-thieno[2,3-b]pyridine) to 1.3 mg/mL (3-pyrrolo[2,3-b]pyridine), however, it was only marginally active against cancer cells. The second strategy involved loading a very potent thieno[2,3-b]pyridine derivative (2) into a cholesteryl-poly(allylamine) polymer matrix for water solubilisation. Suppression of human pancreatic adenocarcinoma (BxPC-3) viability was observed to an IC50 value of 0.5 μg/mL (1.30 μM) in conjunction with the polymer, which is a five-fold (×5) increase in potency as compared to the free drug alone, demonstrating the utility of this formulation approach.
MicroRNA-338-3p Suppresses Proliferation of Human Liver Cancer Cells by Targeting SphK2
Authors: Xiao Geqiong , Wang Qiong , Li Bo , Wu Xiaohui , Liao Hui , Ren Yili , Ai Ning
Published: January 2018

Recent studies have revealed abnormal expression of miRNAs in various tumors. Although microRNA-338-3p (miR-338-3p) plays an important role in many types of tumors, its influence on liver cancer (LC) is unknown. In this study, we found that expression of miR-338-3p was decreased in LC cells and tissues. Colony formation and cell proliferation were suppressed by enhanced expression of miR-338-3p in LC cells. Moreover, miR-338-3p targeted sphingosine kinase 2 (SphK2). Silencing of SphK2 had an identical influence as overexpression of miR-338-3p in LC cells. Overexpression of SphK2 without the 3′-untranslated region remarkably enhanced the growth suppression triggered by miR-338-3p in LC cells. These findings indicate that miR-338-3p influences the development of LC by targeting SphK2, suggesting that miR-338-3p can be targeted as an innovative therapeutic strategy for LC.
Upregulation of Long Noncoding RNA TUG1 Promotes Bladder Cancer Cell Proliferation, Migration, and Invasion by Inhibiting miR-29c
Authors: Guo Peng , Zhang Guohui , Meng Jialin , He Qian , Li Zhihui , Guan Yawei
Published: January 2018

Bladder cancer (BC) is one of the leading causes of cancer-related deaths in the world. Long noncoding RNA (lncRNA) taurine-upregulated gene 1 (TUG1) plays an important role in the development and progression of numerous cancers, including BC. However, the exact role of TUG1 in modulating
BC progression is still poorly known. In this study, we found that TUG1 was upregulated and microRNA-29c (miR-29c) was downregulated in BC tissues and cell lines. Overexpression of TUG1 promoted the cell proliferation of T24 and EJ cells, whereas TUG1 knockdown had the opposite effect. Upregulation
of TUG1 obviously facilitated the migration and invasion of T24 and EJ cells. In contrast, TUG1 silencing repressed the migration and invasion of T24 and EJ cells. Furthermore, TUG1 knockdown markedly increased the expression of miR-29c in vitro. On the contrary, overexpression of TUG1 remarkably
decreased the expression of miR-29c. Transfection with plasmids containing mutant TUG1 has no effect on the expression of miR-29c. There were direct interactions between miR-29c and the binding sites of TUG1. In addition, the inhibitory effects of small interfering RNA specific for TUG1 on
BC cell proliferation, migration, and invasion were reversed by downregulation of miR-29c. Collectively, our study strongly demonstrates that TUG1 promotes BC cell proliferation, migration, and invasion by inhibiting miR-29c, suggesting that lncRNA TUG1 may be a promising target for BC gene therapy.
GASP. VII. Signs of Gas Inflow onto a Lopsided Galaxy
Authors: Vulcani Benedetta , Poggianti Bianca M. , Moretti Alessia , Mapelli Michela , Fasano Giovanni , Fritz Jacopo , Jaffé Yara , Bettoni Daniela , Gullieuszik Marco , Bellhouse Callum
Published: January 2018

Theoretically, inflowing filaments of gas are one of the main causes of growth for a galaxy. Nonetheless, observationally, probing ongoing gas accretion is challenging. As part of the Gas Stripping Phenomena in galaxies with MUSE (GASP) program, we present the analysis of a spiral galaxy at z = 0.04648 whose characteristics indeed are consistent with a scenario in which gas accretion plays a major role. The most salient indirect parts of evidence that support this picture are as follows: (1) The galaxy is isolated, and its position rules out the mechanisms expected in dense environments. (2) It shows a pronounced lopsidedness extending toward the west. According to the spatially resolved star formation history, this component was formed

ago. (3) It has many large and elongated H ii regions that are an indication of a fragmentation due to disk instability. (4) The stellar and gas kinematics are quite symmetric around the same axis, but in the gas the locus of negative velocities shows a convexity toward the east, as if new gas has been infalling with different orientation and velocity. (5) The metallicity distribution is inhomogeneous and shows exceptionally steep gradients from the center toward the outskirts, especially in the southwest side. (6) The luminosity-weighted age is generally low (∼8 Gyr) and particularly low (<7 Gyr) along a trail crossing the galaxy from southwest toward the north. It might trace the path of the accreted gas. These findings point to an inflow of gas probably proceeding from the southwest side of the galaxy.
A Breakout Model for Solar Coronal Jets with Filaments
Authors: Wyper P. F. , DeVore C. R. , Antiochos S. K.
Published: January 2018

Recent observations have revealed that many solar coronal jets involve the eruption of miniature versions of large-scale filaments. Such “mini-filaments” are observed to form along the polarity inversion lines of strong, magnetically bipolar regions embedded in open (or distantly closing) unipolar field. During the generation of the jet, the filament becomes unstable and erupts. Recently we described a model for these mini-filament jets, in which the well-known magnetic-breakout mechanism for large-scale coronal mass ejections is extended to these smaller events. In this work we use 3D magnetohydrodynamic simulations to study in detail three realizations of the model. We show that the breakout-jet generation mechanism is robust and that different realizations of the model can explain different observational features. The results are discussed in relation to recent observations and previous jet models.
Early Observations of the Type Ia Supernova iPTF 16abc: A Case of Interaction with Nearby, Unbound Material and/or Strong Ejecta Mixing
Authors: Miller A. A. , Cao Y. , Piro A. L. , Blagorodnova N. , Bue B. D. , Cenko S. B. , Dhawan S. , Ferretti R. , Fox O. D. , Fremling C. , Goobar A. , Howell D. A. , Hosseinzadeh G. , Kasliwal M. M. , Laher R. R. , Lunnan R. , Masci F. J. , McCully C. , Nugent P. E. , Sollerman J. , Taddia F. , Kulkarni S. R.
Published: January 2018

Early observations of Type Ia supernovae (SNe Ia) provide a unique probe of their progenitor systems and explosion physics. Here we report the intermediate Palomar Transient Factory (iPTF) discovery of an extraordinarily young SN Ia, iPTF 16abc. By fitting a power law to our early light curve, we infer that first light for the SN, that is, when the SN could have first been detected by our survey, occurred only

days before our first detection. In the ∼24 hr after discovery, iPTF 16abc rose by ∼2 mag, featuring a near-linear rise in flux for

days. Early spectra show strong C ii absorption, which disappears after ∼7 days. Unlike the extensively observed Type Ia SN 2011fe, the

colors of iPTF 16abc are blue and nearly constant in the days after explosion. We show that our early observations of iPTF 16abc cannot be explained by either SN shock breakout and the associated, subsequent cooling or the SN ejecta colliding with a stellar companion. Instead, we argue that the early characteristics of iPTF 16abc, including (i) the rapid, near-linear rise, (ii) the nonevolving blue colors, and (iii) the strong C ii absorption, are the result of either ejecta interaction with nearby, unbound material or vigorous mixing of radioactive 56Ni in the SN ejecta, or a combination of the two. In the next few years, dozens of very young normal SNe Ia will be discovered, and observations similar to those presented here will constrain the white dwarf explosion mechanism.
Jean Claude Rouchy et son œuvre : quelques jalons d’une théorisation dans le champ de la clinique psychanalytique du sujet, des groupes, des institutions et de la culture
Authors: Pinel Jean-Pierre
Published: January 2018

Cet article présente, de manière synthétique, le parcours de Jean Claude Rouchy, analyste de sujet, de groupe et d’institution, pionnier dans le champ de la psychosociologie comme dans celui de la clinique des ensembles intersubjectifs et de l’interculturalité, qui a toujours articulé investissement clinique et recherche, engagement associatif et activités éditoriales. Le propos se poursuit, dans une deuxième partie, en dégageant quelques concepts et principes méthodologiques essentiels que nous lui devons. Il aborde notamment les concepts de groupe d’appartenance et d’incorporat et présente les dispositifs d’intervention et d’analyse d’institution établis par J.C. Rouchy. Il se clôt par une exploration du concept de dispositif et esquisse quelques prolongements ouverts par ses travaux.
Interventions et supervisions institutionnelles en échec
Authors: Pinel Jean-Pierre
Published: January 2018

Une revue de la littérature met en évidence que la question de l’échec est relativement marginalisée dans le champ de la clinique psychanalytique et plus encore dans celui de la clinique des interventions et supervisions institutionnelles. L’article se propose d’en ressaisir les raisons. Il propose l’hypothèse centrale selon laquelle l’échec constitue une forme princeps de négativité et, partant, se voit contre-investi, notamment en une période culturelle privilégiant la réussite et l’excellence. En appui sur différentes configurations cliniques issues d’interventions institutionnelles conduites dans des institutions soignantes, l’article montre que différentes modalités de négativité se logent dans ce qui est recouvert par le terme englobant d’« échec ». L’échec prenant ainsi, dans la clinique, les significations extrêmement différentes de symptôme, de moment transitionnel ou enfin de situation d’anéantissement.
Un échec de toute première catégorie
Authors: Combase Catherine
Published: January 2018

Ce texte reprend l’histoire contée par l’écrivain et psychothétapeute Irvin Yalom dans La méthode Shopenhauer (2005). Alors qu’il est atteint d’un cancer incurable, un célèbre psychiatre américain compulse ses dossiers, trente ans de carrière – a-t-il vraiment aidé ses patients ? –, et tombe sur un « échec de toute première catégorie » vécu il y a vingt-cinq ans avec un type froid, manipulateur, asocial, prédateur sexuel, beau mais antipathique, avec lequel il s’était investi à fond pendant trois ans sans pouvoir constater la moindre avancée. Ce patient avait brutalement interrompu la thérapie en expliquant qu’il n’en avait rien tiré. Il décide de le retrouver. Leur deuxième rencontre donne lieu à un véritable thriller. Le thérapeute est cette fois demandeur et le cynique patient compte bien en profiter : il veut devenir thérapeute sans autre motivation que de gagner sa vie...
Delayed Puberty
Authors: Dye Alyssa M. , Nelson Grace B. , Diaz-Thomas Alicia
Published: January 2018

Delayed puberty is defined as the absence of physical signs of puberty 2 to 2.5 standard deviations above the mean age and affects approximately 2% of adolescents. Causes of delayed puberty are broadly divided into two categories: hypergonadotropic hypogonadism and hypogonadotropic hypogonadism. One exception to this classification system is constitutional delay of growth and puberty, the most common cause of delayed puberty. For the general pediatrician, knowledge of the different causes and initial steps to evaluation is crucial when a patient with delayed puberty presents.

[
Pediatr Ann.
2018;47(1):e16–e22.]
Identification of User Preference for Multi-Criteria Reporting in Business Intelligence
Authors: Aruldoss Martin , Travis Miranda Lakshmi , Venkatasamy Prasanna Venkatesan
Published: January 2018

Business intelligence (BI) is an integrated set of tools used to support the transformation of data into information in order to support decision making. Among different functionalities, reporting plays a significant role that provides information to its readers to make better decisions. BI lacks user-specific reporting to the different levels of users of an organization. Different users require different kinds of reporting with respect to different requirement (criteria) in an organization. A multi-criteria reporting (MCR) finds the suitable information to suitable user based on the multiple conflicting preferences of a user. Technique for order preference by similarity to ideal solution (TOPSIS) is the most popularly applied multi-criteria decision-making (MCDM) technique selected to identify different levels of user preference for MCR. Banking business is considered as a case study to identify user preference for MCR. This research also designs evaluation metrics for TOPSIS.
Advances in Green Cloud Computing
Authors: Ahuja Sanjay P. , Muthiah Karthika
Published: January 2018

Cloud computing is witnessing tremendous growth at a time when climate change and reducing emissions from energy use is gaining attention. With the growth of the Cloud, however, comes an increase in demand for energy. There is growing global awareness about reducing greenhouse gas emissions and healthy environments. Green computing in general aims to reduce the consumption of energy and carbon emission and also to recycle and reuse the energy usage in a beneficial and efficient way. Cloud data centers consume inordinate amounts of energy and have significant CO2 emissions. This chapter gives an overview about green cloud computing and its evolution, surveys related work, discusses associated integrated green cloud architecture (green cloud framework), innovations, and technologies, discusses green cloud computing scenarios, and highlights future work and challenges that need to be addressed to sustain an eco-friendly cloud computing environment that is poised for significant growth.
Environmental Sustainability in the Computer Industry for Competitive Advantage
Authors: Rahman Nayem
Published: January 2018

The computer industry is quite often blamed for excessive energy consumption, carbon emissions, and e-waste. Shipment of e-waste to developing countries where it is often disposed of in unsafe ways is another major issue. Implementation of an end-to-end computer and related products sustainability management strategy by incorporating the reuse of existing technology can make a major impact on the environment. Organizations can take sustainability programs as part of business strategies to achieve competitive advantage in the industry. This chapter discusses different aspects of a sustainable computer industry program and proposes that computer makers take ownership of disposing of e-waste by following safety standards. The chapter also proposes adopting a reverse supply chain process for possible reuse, recycle, or disposal of computers. The author also points out that adopting strategic sustainability initiatives can help an organization to achieve competitive advantage.
Biotechnology and Wealth Creation From Plant With Healing Properties
Authors: Ebomoyi E. William
Published: January 2018

The relevance of traditional healing in genomic science pertain to the use of specific herbal remedies which are therapeutic for the management of endemic diseases in developing and the least developed nations. Besides the therapeutic resources of the healers were discussed and in nature of their therapeutic modality was characterized. The physical, mental and social psychological model of traditional healing was developed. It was recommended that genomics specifically true sequencing could be applied to identify the phytochemical agents which are present in many of the herbs which traditional healers use. Among those herbs, those that are lethal and toxic to patients should be expunged.
Nanoencapsulation of Food Ingredients
Authors: Shah Manzoor Ahmad , Mir Shabir Ahmad , Bashir Mudasir
Published: January 2018

Nanoencapsulation of food ingredients is one of the important applications of food nanotechnology. Nanoencapsulation is a technique used to produce nanocapsules from core materials packed within a wall material. Food manufacturers need to incorporate food ingredients with specific functional properties into food products. However, these ingredients may slowly degrade and lose their activity, or become hazardous due to various chemical reactions. They can also react with other components in the food system, which may lower their bioavailability, or change the color or taste of a product, allowing the food item to become prone to spoilage and deterioration. The protection of food ingredients against degradation and interaction with other food components may be done using the nanoencapsulation technique. It also, helps to enhance the bioavailability of food ingredients by protecting them during the digestive processes, improved uptake in the gastrointestinal tract and enhanced transport to the target sites. Nanosized materials provide a larger surface area for interaction with the biological substrates than microsized materials. Various techniques such as emulsification, coacervation, nanoprecipitation, solvent evaporation, spray drying and freeze drying are widely used techniques for nanoencapsulation of food ingredients.
New Herbal Approaches for the Treatment of Diabetic Kidney Diseases and Its Therapeutic Implications
Authors: Yadav Durgavati , Pandey Vivek , Srivastava Shivani , Tripathi Yamini Bhusan
Published: January 2018

Diabetic Kidney Diseases (DKD) is a very serious complication of diabetes. There is recent steep rise in the prevalence of metabolic syndrome and DKD worldwide. Factors responsible for intraglomerular hypertension include activation of various vasoactive systems, polyol pathway, oxidative stress, inflammation and protein kinase C. Sodium-Dependent Glucose Co-Transporter (SGLT-2) inhibitors, DPP-IV (Dipeptidyl peptidase-4) inhibitors are being develop to manage the hyperglycemia and oxidative stress induced inflammatory cascade. Herbal drugs have gained increasing popularity; are complex mixtures of polyphenols and phytochemicals from any raw or processed part of a plant, including leaves. Herbal drugs in this modern era are preferred due to its lesser side effects. Various preparations are presently used for ameliorating the effect of DKD. Since, medicinal plants have been reported to affect various metabolic receptors, enzymes and signaling cascade. Above book chapter explains the involvement of different phytochemicals in biological pathway associated with the kidney damage.
A Comparison of Transport Modes in Terms of Energy Consumption
Authors: Yilmaz Zafer , Erol Serpil , Öcalir-Akunal Ebru Vesile
Published: January 2018

Energy consumption of transport modes are partly dependent on the chosen travel mode. For specific OD pairs a comparison of travel modes in terms of energy consumption gives an idea of the possibilities to change the energy budget of a city. In this study a comparison of transport modes in terms of energy consumption is given for two chosen routes in the case study of Ankara, Turkey. The results show that there are differences with respect to chosen travel mode in terms of energy use and travel cost reflected to traveler for a certain OD couple.
An Overview of Feeder Services in the Era of Mega Containerships
Authors: Polat Olcay
Published: January 2018

In the era of mega containerships, global containership liners design their transportation service as Hub-and-Spoke networks to improve the access to local transportation markets and to reduce operational costs by using short-sea connections for low-volume transportation lines. Feeder services play an irreplaceable role as logistics service provider in global shipping because of considerable benefits resulting from an increased port range, elimination of port restrictions, small sized ships with increased service frequency, the use of mega containerships, savings in network cost, and decreased inland traffic and air-pollution. In addition to main advantages of feeder service, efficient distribution of containers to faraway regions through feeder services out of the main line regions could subsist in a worldwide market. The aim of this chapter is to analyze the role of feeder services in liner shipping and provide information about major challenges that feeder service providers face in planning their logistics networks in the era of mega containerships.
Vehicle to Cloud
Authors: Ozpinar Alper , Yarkan Serhan
Published: January 2018

The population of humanity has become more than seven billion. Daily used devices, machines, and equipment, are also increasing quicker than the human population. The number of mobile devices in use like phones, tablets and IoT devices already passed the two billion barrier and even more than one billion as vehicles are also on the roads. Combining these two will make the one of the biggest Big Data Environment about the daily life of human beings after the use of internet and social applications. For the newly manufactured vehicles, internet operated entertainment and information Systems are becoming a standard equipment delivering such an information to the manufacturers but most of the current vehicles do not have a system like that. This chapter explains the combined version of IoT and vehicles to create a V2C vehicle to cloud system that will create the big data for environmental sustainability, energy and traffic management by different technical and political views and aspects.
Multiobjective Transportation Problem Using Fuzzy Decision Variable Through Multi-Choice Programming
Authors: Maity Gurupada , Roy Sankar Kumar
Published: January 2018

This paper analyzes the study of Multiobjective Transportation Problem (MOTP) under the consideration of fuzzy decision variable. Usually, the decision variable in a Transportation Problem is taken as real variable. But, in this paper, the decision variable in each node is selected from a set of multi-choice fuzzy numbers. Inclusion of multiple objectives into transportation problem with fuzzy decision variable makes it a Multiobjective Fuzzy Transportation Problem (MOFTP). In this paper, a new formulation of mathematical model of MOFTP with fuzzy goal of each objective function is enlisted. Thereafter the solution technique of the formulated model is described through multi-choice goal programming approach. Finally, a numerical example is presented to show the feasibility and usefulness of this article.
On Securing Cloud Storage Using a Homomorphic Framework
Authors: Gupta Daya Sagar , Biswas G. P.
Published: January 2018

In this chapter, a cloud security mechanism is described in which the computation (addition) of messages securely stored on the cloud is possible. Any user encrypts the secret message using the receiver's public key and stores it. Later on, whenever the stored message is required by an authentic user, he retrieves the encrypted message and decrypts it by using his secret key. However, he can also request the cloud for an addition of encrypted messages. The cloud system only computes the requested addition and sends it to the authentic user; it cannot decrypt the stored encrypted messages on its own. This addition of encrypted messages should be the same as the encryption of the addition of original messages. In this chapter, the authors propose a homomorphic encryption technique in which the above-discussed scenario is possible. The cloud securely computes the addition of the encrypted messages which is ultimately the encryption of the addition of the original messages. The security of the proposed encryption technique depends on the hardness of elliptic curve hard problems.
Analysis of a Learning Management System by Using Google Analytics
Authors: Özen Zeki , Kartal Elif , Emre İlkim Ecem
Published: January 2018

Changes and developments in technology are also reflected in user behavior. Therefore, companies that monitor and analyze user behavior to gain competitive advantage will be one step ahead of others. Google Analytics is one of the most popular web analytics tools that perform this function. This chapter observes changes in user habits between 2011 and 2017 by using the Google Analytics data of Enocta Academic Education Platform (EAEP) that offers course content and learning management system (LMS) services for organizations and universities in Turkey. Thus, it advises to LMS providers in terms of improving their software considering changes in user habits. In addition, different approaches of improving e-learning services are discussed. This case study shows that Google Analytics, one of the web analytics tools, can provide useful information for e-learning platform or LMS providers in order to understand behaviors and needs of the visitors as well as their own strengths and weaknesses.
Open Growth
Authors: Ghafele Roya , Gibert Benjamin
Published: January 2018

Open source software (OSS) is well established in sectors as diverse as aviation, health, telecommunications, finance, publishing, education, and government. As nations increasingly rely on knowledge assets to grow, the adoption of OSS will have profound economic consequences. This chapter identifies the mechanisms inherent to OSS production that help fuel innovation in knowledge-based economies. As a collaborative and open production model, OSS is conceptualized as a prototype of open innovation. OSS-related software development jobs are widely diffused throughout the economy, help build a skilled labour force, and offer wages significantly above the national average. OSS is thus believed to be a strong contributor to growth in high-value employment in the US. The authors also posit that, as industries are exposed to the benefits of OSS as a result of the broad diffusion of OSS-related jobs, open innovation processes outside software development may be adopted through a process of learning and imitation.
Conceptual View on Healthcare Digitalization
Authors: Furda Robert , Gregus Michal
Published: January 2018

In this article, the authors focused on research in healthcare digitalization with conjunction to modern technologies, such as Big Data and analytics. To achieve a proper direction at start of the consequent research the authors used the mixed mode of quantitative and qualitative analysis by combination of literature investigation and extended thematic analysis. In the extended thematic analysis of the data corpus the processing of the fourteen steps activity helped to create mind mappings, to recognize the most relevant initial codes, such as “Service”, “ICT/IT”, and “Process”, and to depict the associative relationship of sub-codes to the initial codes for better visibility of results. The composition of forty logical textual sequences of healthcare digitalization themes in discussion confirmed the relevance of initial codes and representativeness to healthcare digitalization. The findings are a step towards enabling the healthcare services innovation, should contribute in higher quality of life, and bring business value to healthcare sector.
Enterprise Personal Analytics
Authors: Clohessy Trevor , Acton Thomas
Published: January 2018

Modern enterprise technological landscapes are being impacted by the increasing individuation of information systems (IS). Consequently, the end-user computing phenomenon is being extended to incorporate a multitude of nascent possibilities for organizations. One promising avenue encompasses the use of business analytics. Common categories of enterprise intelligence analytics are traditionally derived from activity patterns and collaborative routines. The scope of this article focuses on another emergent category of analytics which is referred to as “enterprise personal analytics”. This topic has been only minimally analysed in IS and business intelligence research. This article therefore extends understanding by presenting a grid framework which comprises various combinations of research stakeholder perspectives and concerns. This framework can be used to guide and coalesce future research on illuminating how personal analytics can be used effectively in an enterprise setting.
Research and Application of Adaptive Step Mechanism for Glowworm Swarm Optimization Algorithm
Authors: Wang Hong-Bo , Tian Ke-Na , Ren Xue-Na , Tu Xu-Yan
Published: January 2018

Glowworm Swarm Optimization Algorithm (GSO) is one of new swarm intelligence optimization algorithms in recent years. Its main idea comes from the cooperative behavior source among individuals during the process of courtship and foraging. In this article, in order to improve convergence speed in the late iteration, avoid the algorithm falling into local optimum, and reduce isolated nodes, the Adaptive Step Mechanism Glowworm Swarm Optimization (ASMGSO) is proposed. The main idea of ASMGSO algorithm is as follows: (1) On the basis of SMGSO algorithm, isolated nodes carry out bunching operator firstly, that is to say they are moving to the central position of the group. If the new position is not better than the current position, then isolated nodes perform mutation operation. (2) At the same time, the fixed step mechanism has been improved. The effectiveness of the proposed ASMGSO algorithm is verified through several classic test functions and application in Distance Vector-Hop.
Autonomous Intelligent Robotic Navigation System Architecture With Mobility Service for IoT
Authors: Subbulakshmi T.  , Balaji N.
Published: January 2018

This article presents the platform for autonomous vehicle architecture, navigation optimization and mobility services. The basic approach is to develop an intelligent agent to create a safety journey and redefine the world of transportation. The goal is to eliminate human driving errors and save human life from accidents. AI robots are a concept of future transportation with full automation and self-learning. Velodyne laser sensors are used for obstacle detection and autonomous navigation of ground vehicles and to create 3D images of the surround so that navigation and controls are optimized. In this article, existing system accessibility will be optimized by multiple features. The agent accessibility is improved, and users can access the vehicles through different ways like mobile apps, speech recognition and gestures. This article concentrates on the mobility services of autonomous vehicles.