bluuebunny/crossref_metadata_2025 huggingface dataset:
Slippery Pirates: Generic Conventions and Discursive Instability in John Fletcher and Philip Massinger’s Pirate Plays
Authors: Gruss Susanne
Published: December 2019

The term piracy marks a slippery category in early modern England: as a legal denomination, it describes the feats of armed robbery at sea for which pirates were prosecuted but their state-sanctioned counterparts, privateers, were not; in a seaman’s professional life, being a pirate was often a phase rather than a stable marker of self-identification. Like their real-life models, literary pirates are contradictory creatures—they shed their pirate identity as quickly as they have adopted it, are used for veiled socio-political commentary, or trimmed to size in order to fit generic constraints. The slipperiness of the pirate has made him (and sometimes her) an attractive figure for early modern playwrights. I argue that John Fletcher and Philip Massinger appropriate the discursive instability of piratical individuals for their pirate plays. Rather than looking at the ideological and political implications of piracy, I analyze the pirate figures in Fletcher and Massinger’s The Double Marriage (1621) and The Sea Voyage (1622) as well as in Massinger’s The Renegado (1623–1624) and The Unnatural Combat (1624–1625) as literary creations. Alternating between the heroic and the villainous, their pirates are convenient plot devices that are attuned to the evolving generic conventions of the early Stuart stage in general and early Stuart tragicomedy in particular.
Spatial-Temporal Variability of Soil Organic Matter in Urban Fringe over 30 Years: A Case Study in Northeast China
Authors: Liu Hongbin , Li Shunting , Zhou Yuepeng
Published: December 2019

The study on soil organic matter (SOM) is of great importance to regional cultivated land use and protection. Based on data collected via continuous and high-density soil samples (0–20 cm) and socio-economic data collected from household survey and local bureau of statistics, this study employs geostatistics and economic statistical methods to investigate the spatial-temporal variation of SOM contents during 1980–2010 in the urban fringe of Sujiatun district in Shenyang City, China. We find that: (1) as to temporal variation, SOM contents in the study sites decreased from 30.88 g/kg in 1980 to 22.63 g/kg in 2000. It further declined to 20.07 g/kg in 2010; (2) in terms of spatial variation, the closer to city center, the more decline of SOM contents. Contrarily, SOM contents could even rise in outer suburb area; and (3) SOM content variation may be closely related to human factors such as farmers’ land use target and behaviour including inputs of chemical and organic fertilizers, types of crops and etc. These findings are conductive to grasp the overall trend of SOM variation and the influence of farmers’ land use behaviour on it. Furthermore, they could provide support for policymakers to agricultural planning and land use monitoring, which consequently aids the improvement of soil quality and food production in the urban fringe areas.
PHLDA1 Does Not Contribute Directly to Heat Shock-Induced Apoptosis of Spermatocytes
Authors: Janus Patryk , Mrowiec Katarzyna , Vydra Natalia , Widłak Piotr , Toma-Jonik Agnieszka , Korfanty Joanna , Smolarczyk Ryszard , Widłak Wiesława
Published: December 2019

Spermatocytes are among the most heat-sensitive cells and the exposure of testes to heat shock results in their Heat Shock Factor 1 (HSF1)-mediated apoptosis. Several lines of evidence suggest that pleckstrin-homology-like domain family A, member 1 (PHLDA1) plays a role in promoting heat shock-induced cell death in spermatogenic cells, yet its precise physiological role is not well understood. Aiming to elucidate the hypothetical role of PHLDA1 in HSF1-mediated apoptosis of spermatogenic cells we characterized its expression in mouse testes during normal development and after heat shock. We stated that transcription of Phlda1 is upregulated by heat shock in many adult mouse organs including the testes. Analyzes of the Phlda1 expression during postnatal development indicate that it is expressed in pre-meiotic or somatic cells of the testis. It starts to be transcribed much earlier than spermatocytes are fully developed and its transcripts and protein products do not accumulate further in the later stages. Moreover, neither heat shock nor expression of constitutively active HSF1 results in the accumulation of PHLDA1 protein in meiotic and post-meiotic cells although both conditions induce massive apoptosis of spermatocytes. Furthermore, the overexpression of PHLDA1 in NIH3T3 cells leads to cell detachment, yet classical apoptosis is not observed. Therefore, our findings indicate that PHLDA1 cannot directly contribute to the heat-induced apoptosis of spermatocytes. Instead, PHLDA1 could hypothetically participate in death of spermatocytes indirectly via activation of changes in the somatic or pre-meiotic cells present in the testes.
Genome-Wide Identification and Characterization of the Mitochondrial Transcription Termination Factors (mTERFs) in Capsicum annuum L.
Authors: Tang Bingqian , Xie Lingling , Yi Ting , Lv Junheng , Yang Huiping , Cheng Xiang , Liu Feng , Zou Xuexiao
Published: December 2019

Mitochondrial transcription termination factors (mTERFs) regulate the expression of mitochondrial genes and are closely related to the function of the mitochondrion and chloroplast. In this study, the mTERF gene family in capsicum (Capsicum annuum L.) was identified and characterized through genomic and bioinformatic analyses. Capsicum was found to possess at least 35 mTERF genes (CamTERFs), which were divided into eight major groups following phylogenetic analysis. Analysis of CamTERF promoters revealed the presence of many cis-elements related to the regulation of cellular respiration and photosynthesis. In addition, CamTERF promoters contained cis-elements related to phytohormone regulation and stress responses. Differentially expressed genes in different tissues and developmental phases were identified using RNA-seq data, which revealed that CamTERFs exhibit various expression and co-expression patterns. Gene ontology (GO) annotations associated CamTERFs primarily with mitochondrion and chloroplast function and composition. These results contribute towards understanding the role of mTERFs in capsicum growth, development, and stress responses. Moreover, our data assist in the identification of CamTERFs with important functions, which opens avenues for future studies.
High-Level Production of a Thermostable Mutant of Yarrowia lipolytica Lipase 2 in Pichia pastoris
Authors: Zhou Qinghua , Su Zhixin , Jiao Liangcheng , Wang Yao , Yang Kaixin , Li Wenjuan , Yan Yunjun
Published: December 2019

As a promising biocatalyst, Yarrowia lipolytica lipase 2 (YlLip2) is limited in its industrial applications due to its low thermostability. In this study, a thermostable YlLip2 mutant was overexpressed in Pichia pastoris and its half-life time was over 30 min at 80 °C. To obtain a higher protein secretion level, the gene dosage of the mutated lip2 gene was optimized and the lipase activity was improved by about 89%. Then, the YlLip2 activity of the obtained strain further increased from 482 to 1465 U/mL via optimizing the shaking flask culture conditions. Subsequently, Hac1p and Vitreoscilla hemoglobin (VHb) were coexpressed with the YlLip2 mutant to reduce the endoplasmic reticulum stress and enhance the oxygen uptake efficiency in the recombinant strains, respectively. Furthermore, high-density fermentations were performed in a 3 L bioreactor and the production of the YlLip2 mutant reached 9080 U/mL. The results demonstrated that the expression level of the thermostable YlLip2 mutant was predominantly enhanced via the combination of these strategies in P. pastoris, which forms a consolidated basis for its large-scale production and future industrial applications.
GTP Preference of d-Glycero-α-d-manno-Heptose-1-Phosphate Guanylyltransferase from Yersinia pseudotuberculosis
Authors: Kim Suwon , Kim Mi-Sun , Jo Seri , Shin Dong Hae
Published: December 2019

d-glycero-α-d-manno-heptose-1-phosphate guanylyltransferase (HddC) is the fourth enzyme synthesizing a building component of lipopolysaccharide (LPS) of Gram-negative bacteria. Since HddC is a potential new target to develop antibiotics, the analysis of the structural and functional relationship of the complex structure will lead to a better idea to design inhibitory compounds. X-ray crystallography and biochemical experiments to elucidate the guanine preference were performed based on the multiple sequence alignment. The crystal structure of HddC from Yersinia pseudotuberculosis (YPT) complexed with guanosine 5′-(β-amino)-diphosphate (GMPPN) has been determined at 1.55 Å resolution. Meanwhile, the mutants revealed their reduced guanine affinity, instead of acquiring noticeable pyrimidine affinity. The complex crystal structure revealed that GMPPN is docked in the catalytic site with the aid of Glu80 positioning on the conserved motif EXXPLGTGGA. In the HddC family, this motif is expected to recruit nucleotides through interacting with bases. The crystal structure shows that oxygen atoms of Glu80 forming two hydrogen bonds play a critical role in interaction with two nitrogen atoms of the guanine base of GMPPN. Interestingly, the binding of GMPPN induced the formation of an oxyanion hole-like conformation on the L(S/A/G)X(S/G) motif and consequently influenced on inducing a conformational shift of the region around Ser55.
Nitrido Technetium-99 m Core in Radiopharmaceutical Applications: Four Decades of Research
Authors: Bolzati Cristina , Dolmella Alessandro
Published: December 2019

The knowledge on element 43 (Tc) of the periodic table, built over the years through the contributions given by the close relationship between chemistry and nuclear medicine, allowed the development of new and increasingly effective radiopharmaceuticals useful both as perfusion and target specific imaging agents for SPECT (single photon emission tomography). Among the manifold Tc-compounds, Tc(V) nitrido complexes played a relevant role in the search for new technetium-99m radiopharmaceuticals, providing efficient labeling procedures that can be conveniently exploited for the design and synthesis of agents, also incorporating small organic molecules or peptides having defined structural features. With this work, we present an overview of four decades of research on the chemistry and on the nuclear medicine applications of Tc(V) nitrido complexes.
Effects of the Entomopathogenic Fungus Metarhizium anisopliae on the Mortality and Immune Response of Locusta migratoria
Authors: Jiang Wuji , Peng Yifan , Ye Jiayi , Wen Yiyi , Liu Gexin , Xie Jiaqin
Published: December 2019

Entomopathogenic fungi are the key regulators of insect populations and some of them are important biological agents used in integrated pest management strategies. Compared with their ability to become resistant to insecticides, insect pests do not easily become resistant to the infection by entomopathogenic fungi. In this study, we evaluated the mortality and immune response of the serious crop pest Locusta migratoria manilensis after exposure to a new entomopathogenic fungus strain, Metarhizium anisopliae CQMa421. M. anisopliae CQMa421 could effectively infect and kill the L. migratoria adults and nymphs. The locust LT50 under 1 × 108 conidia/mL concentration of M. anisopliae was much lower than that under conidial concentration 1 × 105 conidia/mL (i.e., 6.0 vs. 11.2 and 5.0 vs. 13.8 for adults and nymphs, respectively). The LC50 (log10) of M. anisopliae against locust adults and nymphs after 10 days was 5.2 and 5.6, respectively. Although the number of hemocytes in L. migratoria after exposure to M. anisopliae did not differ with that in the controls, the enzymatic activity of superoxide dismutase (SOD) and prophenoloxidase (ProPO) did differ between the two treatments. The activities of both SOD and ProPO under the M. anisopliae treatment were lower than that in the controls, except for the ProPO activity at 72 h and the SOD activity at 96 h. Further, the expression of the L. migratoria immune-related genes defensin, spaetzle, and attacin differed after exposure to M. anisopliae for 24 h to 96 h. Taken together, this study indicated that infection with M. anisopliae CQMa421 could cause the death of L. migratoria by interacting with the immune responses of the host, demonstrating that this fungal strain of M. anisopliae can be an efficient biocontrol agent against L. migratoria.
Long-Term Clinical Outcome of First Recurrence Skull Base Meningiomas
Authors: Kuranari Yuki , Tamura Ryota , Tsuda Noboru , Kosugi Kenzo , Morimoto Yukina , Yoshida Kazunari , Toda Masahiro
Published: December 2019

Skull base meningiomas (SBMs) are considered to be less aggressive and have a slower growth rate than non-SBMs. However, SBMs often develop local recurrences after surgical resection. Gross total removal is difficult because SBMs are deep-seated tumors and involve critical neurovascular structures. The treatment strategy for recurrent SBMs remains controversial. The present study aimed to evaluate the long-term clinical course and prognostic factors associated with shorter progression-free survival (PFS) of recurrent SBMs. This retrospective study included 85 recurrent SBMs from 65 patients who underwent surgery from January 2005 to September 2018. Overall survival (OS) and PFS were evaluated, and the associations among shorter PFS and age, sex, tumor size, lesions, World Health Organization (WHO) grading, removal rate, and time since prior surgery were analyzed. The median follow-up period for PFS was 68 months. The 2-, 5-, and 10-year PFS rates were 68.0%, 52.8%, and 22.7%, respectively. WHO grade II or III, multiple lesions, and tumor size were significantly associated with shorter PFS (p < 0.0001, p = 0.030, and p = 0.173, respectively). Although, radiotherapy did not improve PFS and OS for overall patients, PFS of the patients with subtotal and partial removal for WHO grade II SBMs was significantly improved by the radiotherapy. Multivariate analysis identified WHO grade II or III and multiple lesions as independent prognostic factors for shorter PFS (p < 0.0001 and p = 0.040, respectively). It is essential to estimate the risks associated with shorter PFS for patients with recurrent SBMs to aid in the development of appropriate postoperative strategies.
Systematic Evaluation of Systemic Right Ventricular Function
Authors: Schneider Matthias , Beichl Matthias , Nietsche Christian , Beitzke Dietrich , Porenta Gerold , Beran Gilbert , Vonbank Karin , Hauser Jakob , Hengstenberg Christian , Goliasch Georg , Binder Thomas , Gabriel Harald
Published: December 2019

Background: The right ventricle serves as the subaortic systemic ventricle (sysRV) in patients with congenitally corrected transposition of the great arteries (ccTGA) and in patients with transposition of the great arteries (TGA) surgically repaired by an atrial switch. SysRV can lead to late complications, primarily heart failure, significant regurgitation of the systemic atrioventricular (AV) valve, and ventricular arrhythmias with sudden cardiac death. We sought to investigate the value of 2D- and 3D-echocardiographic parameters of sysRV function. Methods: Consecutive adult patients with sysRV who presented at the adult congenital heart disease outpatient clinic were prospectively enrolled. All patients received comprehensive transthoracic echocardiography, including 3D-echocardiography, cardiac magnetic-resonance-imaging (CMR), cardiopulmonary-exercise-testing, and blood analysis for NT-proBNP. Results. A total of 27 patients were included, 18 with TGA and nine with ccTGA. Median age was 37 years (Q1 = 31, Q3 = 44), 44% were male, median NT-proBNP was 189 pg/mL (Q1 = 155, Q3 = 467); sufficient 3D-echocardiography datasets were acquired in 78% of patients. All echocardiographic 2D and 3D volumetric function parameters correlated with CMR data, whereas a correlation was not seen with any of the longitudinal function parameters. NT-proBNP correlated with tricuspid annular plane systolic excursion (r = −0.43, p = 0.02) and CMR ejection fraction (EF) (r = −0.62, p = 0.003). Conclusion: Systematic evaluation of sysRV is complex and should include not only volumetric parameters but also parameters of longitudinal function in addition to measurement of NT-proBNP. In patients with good image quality, 3D-echocardiography can be used to assess volumes and EF.
Antibacterial Activity of Some Flavonoids and Organic Acids Widely Distributed in Plants
Authors: Adamczak Artur , Ożarowski Marcin , Karpiński Tomasz M.
Published: December 2019

Among natural substances widespread in fruits, vegetables, spices, and medicinal plants, flavonoids and organic acids belong to the promising groups of bioactive compounds with strong antioxidant and anti-inflammatory properties. The aim of the present work was to evaluate the antibacterial activity of 13 common flavonoids (flavones, flavonols, flavanones) and 6 organic acids (aliphatic and aromatic acids). The minimal inhibitory concentrations (MICs) of selected plant substances were determined by the micro-dilution method using clinical strains of four species of pathogenic bacteria. All tested compounds showed antimicrobial properties, but their biological activity was moderate or relatively low. Bacterial growth was most strongly inhibited by salicylic acid (MIC = 250–500 μg/mL). These compounds were generally more active against Gram-negative bacteria: Escherichia coli and Pseudomonas aeruginosa than Gram-positive ones: Enterococcus faecalis and Staphylococcus aureus. An analysis of the antibacterial effect of flavone, chrysin, apigenin, and luteolin showed that the presence of hydroxyl groups in the phenyl rings A and B usually did not influence on the level of their activity. A significant increase in the activity of the hydroxy derivatives of flavone was observed only for S. aureus. Similarly, the presence and position of the sugar group in the flavone glycosides generally had no effect on the MIC values.
Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update
Authors: Bulterys Michelle A. , Wagner Bradley , Redard-Jacot Maël , Suresh Anita , Pollock Nira R. , Moreau Emmanuel , Denkinger Claudia M. , Drain Paul K. , Broger Tobias
Published: December 2019

Most diagnostic tests for tuberculosis (TB) rely on sputum samples, which are difficult to obtain and have low sensitivity in immunocompromised patients, patients with disseminated TB, and children, delaying treatment initiation. The World Health Organization (WHO) calls for the development of a rapid, biomarker-based, non-sputum test capable of detecting all forms of TB at the point-of-care to enable immediate treatment initiation. Lipoarabinomannan (LAM) is the only WHO-endorsed TB biomarker that can be detected in urine, an easily collected sample. This status update discusses the characteristics of LAM as a biomarker, describes the performance of first-generation urine LAM tests and reasons for slow uptake, and presents considerations for developing the next generation of more sensitive and impactful tests. Next-generation urine LAM tests have the potential to reach adult and pediatric patients regardless of HIV status or site of infection and facilitate global TB control. Implementation and scale-up of existing LAM tests and development of next-generation assays should be prioritized.
Cervical Lymph Nodes Detected by F-18 FDG PET/CT in Oncology Patients: Added Value of Subsequent Ultrasonography for Determining Nodal Metastasis
Authors: Yoon Seokho , Ryu Kyeong Hwa , Baek Hye Jin , Kim Tae Hoon , Moon Jin Il , Choi Bo Hwa , Park Sung Eun , Ha Ji Young , Song Dae Hyun , An Hyo Jung , Heo Young Jin
Published: December 2019

Background and Objectives: To investigate the diagnostic performance of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) and subsequent ultrasonography (US) for determining cervical nodal metastasis in oncology patients. Materials and Methods: Fifty-nine cervical lymph nodes (LNs) initially detected by PET/CT with subsequent neck US were included in this retrospective study. All LNs were subjected to US-guided fine-needle aspiration or core needle biopsy. The maximum standardized uptake value (SUVmax) and sonographic features were assessed. Results: Forty-three of 59 cervical LNs detected by PET/CT were malignant. PET/CT alone showed a highest diagnostic value for metastatic LNs with 81.4% sensitivity, 68.8% specificity, and 78% accuracy when SUVmax ≥5.8 was applied as an optimal cut-off value. Combined PET/CT and subsequent US diagnoses for determining nodal metastasis showed the following diagnostic performance: 81.4% sensitivity, 87.5% specificity, and 83.1% accuracy. There was a significant difference in the diagnostic performance between the two diagnostic imaging approaches (p = 0.006). Conclusions: Combined diagnosis using subsequent US showed a significantly higher diagnostic performance for determining nodal metastasis in the neck. Therefore, we believe that our proposed diagnostic strategy using subsequent US can be helpful in evaluating cervical LNs on PET/CT. Moreover, our results clarify the need for US-guided tissue sampling in oncology patients.
Dynamic Behaviors and Microstructure Evolution of Iron–Nickel Based Ultra-High Strength Steel by SHPB Testing
Authors: Fu Hongge , Wang Xibin , Xie Lijing , Hu Xin , Umer Usama , Rehman Ateekh Ur , Abidi Mustufa Haider , Ragab Adham E.
Published: December 2019

Iron–nickel based ultra-high strength steel (wt. 18~20% Ni) is characterized by its high strength and low thermal conductivity, and is normally used to make key components by forming and machining processes. The optimization of these processes is based on a deep understanding of the mechanical and dynamic behaviors under high strain, high strain rate, and high temperature. In this paper, the relationship of stress to strain, strain rate, and temperature is systematically investigated by the dynamic compression tests combined with quasi-static compression tests, and the hardening and softening is associated with the transformation in microstructures. According to the analysis, dynamic recrystallization around 600 °C is assumed to be one important influencing factor, hence hot deformation equations are established and the critical strain for dynamic recrystallization and the volume fraction of the dynamic recrystallized grains are defined.
Mineralogy and Geochemistry of Late Permian Coals within the Tongzi Coalfield in Guizhou Province, Southwest China
Authors: Li Baoqing , Zhuang Xinguo , Querol Xavier , Moreno Natalia , Yang Linjian , Shangguan Yunfei , Li Jing
Published: December 2019

The lowermost Late Permian coal seam (C4 Coal) in the Tongzi Coalfield offers an opportunity to investigate the influence of terrigenous detrital materials from the Qianbei Upland on the mineralogical and geochemical patterns of the C4 Coal. The minerals are mainly dominated by pyrite and, to a lesser extent, tobelite, kaolinite, and calcite, along with traces of Al-oxyhydroxide minerals. The various degrees of marine influence may have resulted in the variation in the amount of Fe-sulfides (e.g., pyrite) and elements having Fe-sulfides affinity. Furthermore, the abundant Fe ions involved in the formation of Fe-sulfides were most likely derived from the claystone on the Qianbei Upland. The tobelite identified in the C4 Coal probably originated from the interaction between pre-existing kaolinite and NH4+ from NH3 released from the thermally affected organic matter at least shortly after the highly volatile bituminous stage under NH4+-rich and K+-poor conditions. The terrigenous detrital materials were derived from two possible sediment-region sources—the Qianbei Upland and Kangdian Upland—which is different from Late Permian coals in Western Guizhou Province. The claystone on the Qianbei Upland may have served as parent rock, as indicated by the presence of the Al-oxyhydroxide minerals as well as low SiO2/Al2O3 ratio (0.66 on average) and low quartz content. Meanwhile, the detrital materials from the Kangdian Upland most likely originated from the erosion of the felsic rocks at the uppermost part of the Kangdian Upland, as evidenced by the high Al2O3/TiO2 ratio (36.0 on average) and the strongly negative Eu anomaly (0.61 on average).
Investigation of Plasma-Assisted Functionalization of Graphitic Materials for Epoxy Composites
Authors: Boaretti Carlo , Roso Martina , Bonora Renato , Modesti Michele , Lorenzetti Alessandra
Published: December 2019

In this study we evaluated the effect of microwave vacuum plasma for the surface functionalization of graphitic fillers (graphite and graphene); we also showed the effect of the functionalization on the mechanical and electrical properties of epoxy composites. Optimized conditions of plasma treatment were defined to obtain high plasma density and increased surface hydrophilicity of the fillers, with high stability of functionalization over time and temperature. However, the extent of such treatments proved to be limited by the high temperatures involved in the curing process of the resin. The use of specific gas mixtures (He/O2) during functionalization and the use of a high surface filler (graphene) can partially limit these negative effects thanks to the higher thermal stability of the induced functionalization. As a consequence, mechanical tests on graphene filled epoxies showed limited improvements in flexural properties while electrical resistivity is slightly increased with a shift of the percolation threshold towards higher filler concentration.
Animal Protein Intake Is Associated with General Adiposity in Adolescents: The Teen Food and Development Study
Authors: Segovia-Siapco Gina , Khayef Golandam , Pribis Peter , Oda Keiji , Haddad Ella , Sabaté Joan
Published: December 2019

Protein plays a crucial role in the growth and development of adolescents. However, being a secondary energy source, protein’s role in obesity has been sidelined. We examined whether intake of protein (total, animal, plant), branched-chain (BCAAs), and sulfur-containing (SCAAs) amino acids are associated with general body and central obesity and body composition in a cross-sectional study among healthy adolescents. Students aged 12–18 years old (n = 601) in schools near two major Adventist universities in California and Michigan provided dietary data via a validated web-based food frequency questionnaire (FFQ) and anthropometric data during school visits. Intakes of total, animal, and plant proteins, and BCAAs and SCAAs were derived from FFQ data. We defined general body obesity with body-mass-index-for-age (BMIz) z-scores and central obesity with waist-to-height ratios (WHtR). After full adjustment for covariates, multiple regression analyses showed significant positive associations between intakes of total protein (β = 0.101, 95% CI: 0.041, 0.161), animal protein (β = 0.118, 95% CI: 0.057, 0.178), BCAAs (β = 0.056, 95% CI: 0.025, 0.087), and SCAAs (β = 0.025, 95% CI: 0.012, 0.038) with general body adiposity. Animal protein (β = 0.017, 95% CI: 0.001, 0.033) and SCAAs (β = 0.004, 95% CI: 0.000, 0.008) were also associated with central obesity. Total and animal protein and BCAA and SCAA were also significantly associated with fat mass. Our findings suggest that high protein intake may pose a possible detriment to adolescent health. Longitudinal and safety evaluation studies are recommended.
Erratum: Elansary et al., 5-Aminolevulinic Acid and Soil Fertility Enhance the Resistance of Rosemary to Alternaria dauci and Rhizoctonia solani and Modulate Plant Biochemistry. Plants 2019, 8, 585
Authors: Elansary Hosam O. , O. El-Ansary Diaa , A. Al-Mana Fahed
Published: December 2019

The authors wish to make the following corrections to their paper [...]
Photo-Actuation of Liquid Crystalline Elastomer Materials Doped with Visible Absorber Dyes under Quasi-Daylight
Authors: Qin Ban , Yang Wenlong , Xu Jiaojiao , Wang Xiuxiu , Li Xiangman , Li Chensha , Gao Yachen , Wang Qiao-e
Published: December 2019

We studied the effect of visible absorber dyes on the photo-actuation performances of liquid crystalline elastomer (LCE) materials under quasi-daylight irradiation. The dye-doped LCE materials were prepared through infiltrating visible absorber dyes into a polysiloxane-based LCE matrix based on its solvent-swollen characteristic. They demonstrated well absorption properties in visible spectrum range and performed strong actuation upon the irradiation from quasi-daylight source, thus indicating that the presence of visible absorber dyes effectively sensitized the LCE materials to light irradiation since the light energy was absorbed by the dyes and then converted into heat to trigger the phase change of LCE matrix. The photo-actuation properties of dye-doped LCE materials with different visible absorber dyes, varied dye contents, and irradiation intensities were investigated. It was shown that the visible absorber dyes with different absorption bands created different photo-actuation performances of LCE materials, the one whose absorption band is near the intensity peak position of quasi-daylight spectrum created the optimum photo-actuation performance. The result disclosed a valuable light utilization way for photo-controlled LCE materials since it revealed that a light-absorbing dye, whose absorption band is in the high intensity region of light spectrum, is capable of effectively utilizing light energy to drive the actuation of LCE materials.
The Influence of Compatibility on the Structure and Properties of PLA/Lignin Biocomposites by Chemical Modification
Authors: Guo Jianbing , Chen Xiaolang , Wang Jian , He Yong , Xie Haibo , Zheng Qiang
Published: December 2019

Lignin, a natural amorphous three-dimensional aromatic polymer, is investigated as an appropriate filler for biocomposites. The chemical modification of firsthand lignin is an effective pathway to accomplish acetoacetate functional groups replacing polar hydroxyl (–OH) groups, which capacitates lignin to possess better miscibility with poly(lactic acid) (PLA), compared with acidified lignin (Ac-lignin) and butyric lignin (By-lignin), for the sake of blending with poly(lactic acid) (PLA) to constitute a new biopolymer based composites. Generally speaking, the characterization of all PLA composites has been performed taking advantage of Fourier transform infrared (FTIR), scanning electron microscopy (SEM), dynamic Mechanical analysis (DMA), differential scanning calorimeter (DSC), thermogravimetric analysis (TGA), rheological analysis, and tensile test. Visibly, it is significant to highlight that the existence of acetoacetate functional groups enhances the miscibility, interfacial compatibility, and interface interaction between acetoacetate lignin (At-lignin) and PLA. Identical conclusions were obtained in this study where PLA/At-lignin biocomposites furthest maintain the tensile strength of pure PLA.
Development and Application of a Performance and Operational Feasibility Guide to Facilitate Adoption of Soil Moisture Sensors
Authors: Kukal Meetpal S. , Irmak Suat , Sharma Kiran
Published: December 2019

Soil moisture sensors can be effective and promising decision-making tools for diverse applications and audiences, including agricultural managers, irrigation practitioners, and researchers. Nevertheless, there exists immense adoption potential in the United States, with only 1.2 in 10 farms nationally using soil moisture sensors to decide when to irrigate. This number is much lower in the global scale. Increased adoption is likely hindered by lack of scientific support in need assessment, selection, suitability and use of these sensors. Here, through extensive field research, we address the operational feasibility of soil moisture sensors, an aspect which has been overlooked in the past, and integrate it with their performance accuracy, in order to develop a quantitative framework to guide users in the selection of best-suited sensors for varying applications. These evaluations were conducted for nine commercially available sensors under silt loam and loamy sand soils in irrigated cropland and rainfed grassland for two different installation orientations [sensing component parallel (horizontal) and perpendicular (vertical) to the ground surface] typically used. All the sensors were assessed for their aptness in terms of cost, ease of operation, convenience of telemetry, and performance accuracy. Best sensors under each soil condition, sensor orientation, and user applications (research versus agricultural production) were identified. The step-by-step guide presented here will serve as an unprecedented and holistic adoption-assisting resource and can be extended to other sensors as well.
Decomposition Analysis of CO2 Emissions Embodied in the International Trade of Russia
Authors: Sun Chuanwang , Chen Lanyun , Huang Guangxiao
Published: December 2019

Our study improves the decomposition method based on the input–output approach to analyze CO2 emissions embodied in the international trade of Russia over the period from 1995 to 2014. The research finds out that carbon was transferred from the upstream resource sectors to the downstream manufacturing sectors and service sectors in Russia. Moreover, Russia was a net exporter of CO2 emissions. 31.46% of Russia’s CO2 emissions were generated for other countries’ consumption in 1999 while 10.68% in 2013. Basic resource and energy sectors were the significant emitters of exporting CO2 emissions. Sectors from traditional manufacturing industries and modern technical industries played an important role in importing embodied CO2 emissions of Russia. Moreover, the effect of modern technical industries on importing embodied CO2 emissions was increasing. The period after 2003 witnessed a substantial decline in Russia’s carbon intensities, which was majorly due to the transformation of the energy structure. Decomposition analysis of CO2 emissions embodied in the international trade can show the trading effect on embodied CO2 emissions from both exporting and importing perspectives. Russia’s case is able to provide instructive implications to the global climate mitigation policy. Countries that burden CO2 emissions for other countries’ consumption are encouraged to participate in the climate negotiation effectively and internalize environmental costs by products’ and services’ pricing in the international trade.
Industry-Specific and Macroeconomic Determinants of Non-Performing Loans: A Comparative Analysis of ARDL and VECM
Authors: Zheng Changjun , Bhowmik Probir Kumar , Sarker Niluthpaul
Published: December 2019

With the growth of an economy, the banking industry expands and the competitiveness becomes intense with the increased number of banks in the economy. The objective of this research was to discover the influence of industry-specific and macroeconomic determinants of non-performing loans (NPLs) in the entire banking system of Bangladesh. We performed an analysis for the period from 1979 to 2018 by an autoregressive distributed lag (ARDL) model and checked the robustness of the results in the vector error correction (VEC) model. The outcomes of this research suggest that both industry-specific and macroeconomic factors influence NPLs significantly. Among the industry-specific determinants, bank loan growth, net operating profit, and deposit rates negatively impact NPLs with statistical significance while bank liquidity and lending rates have a significant positive affiliation with NPLs. Gross domestic product (GDP) growth and unemployment, among the macroeconomic variables, have a negative connection with NPLs. Whereas, domestic credit and exchange rates have a significant positive association with NPLs. The contribution of this research is that the outcomes found by means of econometric models can be used for predicting and measuring NPLs in upcoming years, not only for Bangladesh but also for developing and emerging economies. Individual banks, as well as the banking sector, by and large, can get a guideline from this research.
The Role of Volunteer Participation and Person-Organization Fit in the Relationship between Motives and Psychological Well-Being
Authors: Chung Yang Woon , Im Seunghee , Kim Jung Eun
Published: December 2019

(1) Background: Studies have been limited in explaining how volunteering acts as underlying mechanisms that associate the antecedents and outcomes of volunteering. This study aims to investigate whether volunteer participation mediates the relationship between motives (self-oriented and other-oriented) and psychological well-being, and further whether person-organizational (PO)-fit moderates the relationship between motives and volunteer participation. (2) Methods: Data were collected from full-time employees in organizations in South Korea using a self-administered instrument. To test the hypotheses, hierarchical regression analyses and path analyses were conducted. (3) Results: Volunteer participation showed a significant mediating effect only for the relationship between other-oriented motives and psychological well-being. PO fit showed a significant moderating role, and further analysis revealed that the mediated moderation of PO-fit was significant. (4) Conclusions: Results suggest that employees with other-oriented motives and PO fit were more likely to participate in volunteer activities, which then increased one’s psychological well-being. Findings provide insights for HR practitioners regarding employee volunteering programs.
Solutions for the Sustainable Management of a Cultural Landscape in Danger: Mar Menor, Spain
Authors: Montealegre María Griñán
Published: December 2019

The focus of this paper is a case study on the municipality of San Javier in Spain. The aim of the analysis was to provide a working model for the integration of the assessment and conservation of built heritage into broader projects devoted to the sustainable restoration of natural spaces undergoing evident declines in habitability. With a population of 31,905, San Javier is located on the edge of the Mar Menor, which is one of the largest permanent salt water lagoons in the Mediterranean. It forms part of the coastal region of the Autonomous Community of the Region of Murcia in the southeast of the Iberian Peninsula. San Javier is one of four municipalities that administer this unique ecosystem. However, despite being designated as a protected natural site since its 14 beaches are one of the most important national and international tourist destinations in this Autonomous Community, since 2016, it has suffered one of the worst environmental crises in its history. One of the outcomes of this situation is that the government bodies involved have begun to seek new models for the area’s complete regeneration that would enable sustainable growth and also include the social and economic sectors that have, to date, played a secondary role in managing the area. In this regard, cultural heritage should play a key role. The aim of this study was to demonstrate that the region’s cultural heritage, despite the complex issues involved in its management, especially for the local administrative bodies, can contribute to the creation of new models for regeneration. Besides the added value of cultural prestige provided by this area’s unique cultural landscape, which is a further legacy of the region’s history and artistic development, engaging with cultural heritage facilitates the revival of traditional systems that contribute to environmental improvement. Finally, this paper provides tools that enable local groups, and, above all, the residents themselves, to identify with the values of their cultural heritage.
Study on Dynamic Structure-Soil-Structure Interaction of Three Adjacent Tall Buildings Subjected to Seismic Loading
Authors: Gan Jinsong , Li Peizhen , Liu Qiang
Published: December 2019

The dynamic structure-soil-structure interaction (SSSI) involving three adjacent structures with pile-raft foundations arranged along the east-west direction in a viscoelastic half-space is numerically studied under earthquake excitation. The direction of earthquake excitation is perpendicular to the direction of the structural arrangement. In the simulation, the Davidenkov model of the soil skeleton curve is assumed for soil behavior, and the viscous-spring artificial boundary is adopted. In order to investigate the effects of SSSI, the clear distance between structures, structure types, structure heights, and the first natural periods of structures are considered, and a series of numerical simulations are conducted. The peak floor displacement and the peak inter-story shear force of structures are examined to determine the SSSI effects. Results show that SSSI effects change significantly with these factors. Furthermore, the structural seismic response could be increased or reduced as a result of SSSI, depending mainly on the structural characteristics, rather than the location of the structures. These results are significant for studying the effects of SSSI and the sustainable development of cities, especially for the seismic design of dense urban buildings.
Two-Dimensional Layered Nanomaterial-Based Electrochemical Biosensors for Detecting Microbial Toxins
Authors: Li Zhuheng , Li Xiaotong , Jian Minghong , Geleta Girma Selale , Wang Zhenxin
Published: December 2019

Toxin detection is an important issue in numerous fields, such as agriculture/food safety, environmental monitoring, and homeland security. During the past two decades, nanotechnology has been extensively used to develop various biosensors for achieving fast, sensitive, selective and on-site analysis of toxins. In particular, the two dimensional layered (2D) nanomaterials (such as graphene and transition metal dichalcogenides (TMDs)) and their nanocomposites have been employed as label and/or biosensing transducers to construct electrochemical biosensors for cost-effective detection of toxins with high sensitivity and specificity. This is because the 2D nanomaterials have good electrical conductivity and a large surface area with plenty of active groups for conjugating 2D nanomaterials with the antibodies and/or aptamers of the targeted toxins. Herein, we summarize recent developments in the application of 2D nanomaterial-based electrochemical biosensors for detecting toxins with a particular focus on microbial toxins including bacterial toxins, fungal toxins and algal toxins. The integration of 2D nanomaterials with some existing antibody/aptamer technologies into electrochemical biosensors has led to an unprecedented impact on improving the assaying performance of microbial toxins, and has shown great promise in public health and environmental protection.
Quantum Mixmaster as a Model of the Primordial Universe
Authors: Bergeron Hervé , Czuchry Ewa , Gazeau Jean Pierre , Małkiewicz Przemysław
Published: December 2019

The Mixmaster solution to Einstein field equations was examined by C. Misner in an effort to better understand the dynamics of the early universe. We highlight the importance of the quantum version of this model for the early universe. This quantum version and its semi-classical portraits are yielded through affine and standard coherent state quantizations and more generally affine and Weyl–Heisenberg covariant integral quantizations. The adiabatic and vibronic approximations widely used in molecular physics can be employed to qualitatively study the dynamics of the model on both quantum and semi-classical levels. Moreover, the semi-classical approach with the exact anisotropy potential can be effective in the numerical integration of some solutions. Some promising physical features such as the singularity resolution, smooth bouncing, the excitation of anisotropic oscillations and a substantial amount of post-bounce inflation as the backreaction to the latter are pointed out. Finally, a realistic cosmological scenario based on the quantum mixmaster model, which includes the formation and evolution of local structures is outlined.
Biogeochemistry and Water–Rock Interactions of Coalbed Methane Co-Produced Water in the Shizhuangnan Block of the Southern Qinshui Basin, China
Authors: Li Yang , Tang Shuheng , Zhang Songhang , Xi Zhaodong , Wang Pengfei
Published: December 2019

Coalbed methane is a major unconventional resource that has been exploited commercially for decades in the southern Qinshui Basin of China. The hydrogeochemical characteristics of coal reservoir water play a key role in the exploration and development of coalbed methane resources. In view of this, a detailed study was performed on coalbed methane co-produced water collected from the Shizhuangnan block to assess water–rock interactions and biogeochemical processes. Water samples were analyzed to establish major ions, isotopic compositions and perform 16S rRNA sequencing. Results suggest that the hydrochemistry was controlled by water–rock processes and that methane was consumed by sulfate reduction through calculation. Meanwhile, the isotopic compositions of water samples indicated that they had a predominantly meteoric origin and were influenced by microbial activity. The 16S rRNA sequencing results of bacteria and archaea provide an important foundation for understanding the activity of sulfate-reducing bacteria and methanogens at different hydraulic heads, which was consistent with isotopic analysis. Carbonates containing calcite and dolomite were found to be distributed at different hydraulic head due to the biogeochemical characteristics and associated water–rock interactions.
Pump Efficiency Analysis for Proper Energy Assessment in Optimization of Water Supply Systems
Authors: Martin-Candilejo Araceli , Santillán David , Garrote Luis
Published: December 2019

Water supply systems need to be designed accounting for both construction and operational costs. When the installation requires water pumping, it is key for the operational costs to know how well the pump can perform. So far, pump efficiency has been considered using conservative values, in the absence of a better estimation. The aim of this paper was to improve determining the energy costs by clarifying what the value of the pump performance should be. For this, 226 commercial pumps were studied, registering the efficiency at the optimum operating point, as well as other variables such as the flow rate, height, and pump type. As a result, a strong relationship between the pump performance and the discharge flow was spotted. That allowed the generation of an empirical curve, which can be used by designers to anticipate what pump efficiency can be expected. The results are used in a simple case study using the Granados Optimization System. These achievements can be implemented in design policies for a better energy assessment in the optimization of water supply systems.