bluuebunny/crossref_metadata_2025 huggingface dataset:
Systems Immunology: Revealing Influenza Immunological Imprint
Authors: Tomic Adriana , Pollard Andrew J. , Davis Mark M.
Published: May 2021

Understanding protective influenza immunity and identifying immune correlates of protection poses a major challenge and requires an appreciation of the immune system in all of its complexity. While adaptive immune responses such as neutralizing antibodies and influenza-specific T lymphocytes are contributing to the control of influenza virus, key factors of long-term protection are not well defined. Using systems immunology, an approach that combines experimental and computational methods, we can capture the systems-level state of protective immunity and reveal the essential pathways that are involved. New approaches and technological developments in systems immunology offer an opportunity to examine roles and interrelationships of clinical, biological, and genetic factors in the control of influenza infection and have the potential to lead to novel discoveries about influenza immunity that are essential for the development of more effective vaccines to prevent future pandemics. Here, we review recent developments in systems immunology that help to reveal key factors mediating protective immunity.
Assessment of the Environmental Impact of Acid Mine Drainage on Surface Water, Stream Sediments, and Macrophytes Using a Battery of Chemical and Ecotoxicological Indicators
Authors: Alvarenga Paula , Guerreiro Nádia , Simões Isabel , Imaginário Maria José , Palma Patrícia
Published: May 2021

Mining activities at the Portuguese sector of the Iberian Pyrite Belt (IPB) have been responsible for the pollution of water, sediments, and biota, caused by the acid mine drainage (AMD) from the tailing deposits. The impact has been felt for years in the rivers and streams receiving AMD from the Aljustrel mine (SW sector of the IPB, Portugal), such as at the Água Forte stream, a tributary of the Roxo stream (Sado and Mira Hydrographic Region). To evaluate the extent of that environmental impact prior to the remediation actions, surface water, sediments, and the macrophyte Scirpus holoschoenus L. were sampled at the Água Forte and the Roxo streams, upstream and downstream from the confluence. The surface water and the sediments were extremely acidic at the Água Forte stream (pH ranges 2.22–2.92 for the water and 2.57–3.32 for the sediment), with high As, Cu, Pb, and Zn concentrations of 2.1, 120, 0.21, and 421 mg kg−1, respectively, in the water, and 661, 1746, 539, and 1994 mg kg−1, respectively, in the sediment, in the location closer to the mine. Two aquatic bioassays evidenced the high ecotoxicity of the Água Forte water at that site, with very low EC50 values for Vibrio fischeri luminescence inhibition (<3.1% v/v) and Daphnia magna 48-hour immobilization/mortality assays (<6.3% v/v). The impact of the AMD was also evident in the sediments of the Roxo stream, but not so marked in the water, with circa neutral pH and lower As, Cu, Pb, and Zn concentrations. Consistently, the ecotoxicological response was only felt in the sampling point closer to the confluence of the Água Forte with the Roxo stream, with an EC20 of 27.0% (v/v) towards the V. fischeri. One of the dominant and well adapted macrophytes, S. holoschoenus L., presented low bioaccumulation factors for Cu (0.04) and Zn (0.15) in their emerging parts, and very low concentrations for As and Pb, making this plant a potential candidate to be used in phytoremediation actions to treat and control AMD in the IPB.
Real-Time Determination of Total Solids in UASB Reactors Using a Single Emitter Ultrasonic Sensor
Authors: Neves Priscilla N. P. , Azevedo Lariza S. , Hoep Martijn , Bressani-Ribeiro Thiago , Wiersma Matthijs , Ferreira Ronaldo N. , Wagterveld R. Martijn , Yntema Doekle , Chernicharo Carlos A. L. , Agostinho Luewton L. F.
Published: May 2021

The lack of proper sludge withdrawal routines has been one of the main causes of solids washout and consequent deterioration of effluent quality from up-flow anaerobic sludge blanket (UASB) reactors treating sewage in developing countries. The establishment of an adequate sludge withdrawal routine depends on the knowledge of the sludge mass inside the reactor, but for this, it is necessary to continuously monitor the solid’s profile along the height of the digestion compartment of such reactors. Knowing the sludge concentration at the highest point of this compartment, immediately before the passage of the liquid to the settling compartment, allows the definition of more robust strategies for sludge discharge, in order to not exceed the retention capacity (storage) of solids in the reactor. To couple with that, a low-cost ultrasound sensor was developed and tested with the aim of monitoring total solids concentration inside UASB reactors. Bench and demo-scale tests were performed to validate the developed technology. Results have shown that the sensor can provide real-time values of total solids inside the reactor with 0.1% accuracy up to 1% total solids content.
ECONOMIC BEHAVIOR AND DECISION MAKING: СASE STUDY
Authors: Kononovich T. , Nepokupna T. , Mіаsoid K.
Published: May 2021

The subject of the article is the process of making an economic decision. The stages of the history of economic-psychological researches – economic psychology, behavioral economy, psychology of economic behavior are distinguished. The contribution to the study of the psychological factors of the economic behavior of the winners of the Nobel Prize in Economics is shown. The theory of rational expectations of John von Neumann and O. Morgerstern Is characterized, particular attention is paid to the prospect theory of D. Kaneman and A. Tversky. The latter is presented in the form of heuristic decision making – representativeness, availability, adjustment, and anchoring, in addition, with the distinction of rational and irrational moments of this process. It is stated that the corresponding model of decision making does not take into account and that behind the economic- psychological lies in the actual psychological logic that a person makes decisions based on his own strategy, coping. The concept of decision making is substantially incomplete. Opportunity of the possibility of specification of the prospect theory of by the Case Study method – the analysis of a particular case of economic behavior opens. The Melbourne decision making questionnaire applies, the factors of this process – vigilance, back-passing, procrastination, and hypervigilance are manifest. The investigator is given the instruction to make an expanded comment on every statement, to explain own argumentation, as well as the obtained result. The rational and irrational components of its solution and features of coping are analyzed. It is determined that vigilance is the dominant factor, it turns out to be the most productive way of decision making. A model of coping of decision making, which specifies the theory of the prospects of D. Kaneman and A. Tversky and expands the limits of its application in the field of psychology of human economic behavior, is constructed.
Susceptibilidad a ceftolozano-tazobactam y ceftazidima-avibactam de Pseudomonas aeruginosa resistente a carbapenémicos
Authors: Guajardo-Lara Claudia Elena , Hernández-Galván Nayelly Nohemi , Ayala-Gaytán Juan Jacobo , Valdovinos-Chávez Salvador Bruno
Published: May 2021

Pseudomonas aeruginosa ha sido considerada por la Organización Mundial de la Salud (OMS) de importancia para la investigación de nuevos antibióticos. Revisamos la susceptibilidad in vitro y la producción de carbapenemasas de ceftolozano-tazobactam (C-T) y ceftazidima-avibactam (CZA), a P. aeruginosa no susceptible a carbapenémicos. Se recolectaron aislados clínicos de P. aeruginosa resistentes a carbapenémicos. La susceptibilidad a C-T y CZA se determinó mediante el método de Kirby-Bauer, además, se utilizó la técnica de inhibición de carbapenémicos modificada. Cuarenta y siete de 330 cepas (14,2%) fueron resistentes a carbapenémicos (> 90% MDR), 30 (63,8%) fueron susceptibles a CZA y 12 (25,2%) a C-T. Se detectaron carbapenemasas en 11 de 37 cepas (29,7%) y metalo-β-lactamasas (MBL) en diez. Las cepas de P. aeruginosa resistentes a carbapenémicos fueron MDR y susceptibilidad a C-T y CZA de menos del 80%.
Multiplex Serum Biomarker Assays Improve Prediction of Renal and Mortality Outcomes in Chronic Kidney Disease
Authors: Martin William P. , Conroy Chloe , Naicker Serika D. , Cormican Sarah , Griffin Tomás P. , Islam Md Nahidul , McCole Eibhlin M. , McConnell Ivan , Lamont John , FitzGerald Peter , Ferguson John P. , Richardson Ciarán , Logue Susan E. , Griffin Matthew D.
Published: May 2021

Key Points

Incorporation of 11 serum biomarkers alongside clinical variables improved prediction of adverse CKD outcomes over 5-year follow-up.

Patients with the triad of high sTNFR1 and NGAL coupled with low C3a-desArg had particularly high adverse event rates during follow-up.

Biomarkers were quantified on a single, clinical-grade analyzer, with potential for improved translatability to the CKD outpatient setting.

Background

We investigated the predictive value of 11 serum biomarkers for renal and mortality end points in people with CKD.

Methods

Adults with CKD (n=139) were enrolled from outpatient clinics between February 2014 and November 2016. Biomarker quantification was performed using two multiplex arrays on a clinical-grade analyzer. Relationships between biomarkers and renal and mortality end points were investigated by random forests and Cox proportional hazards regression.

Results

The cohort was 56% male. The mean age was 63 years and median (IQR) CKD-EPI eGFR was 33 (24–51) ml/min per BSA. A total of 56 (40%) people developed a composite end point defined as ≥40% decline in eGFR, doubling of serum creatinine, RRT, or death over median (IQR) follow-up of 5.4 (4.7–5.7) years. Prediction of the composite end point was better with random forests trained on serum biomarkers compared with clinical variables (area under the curve of 0.81 versus 0.78). The predictive performance of biomarkers was further enhanced when considered alongside clinical variables (area under the curve of 0.83 versus 0.81 for biomarkers alone). Patients (n=27, 19%) with high soluble TNF receptor-1 (≥3 ng/ml) and neutrophil gelatinase-associated lipocalin (≥156 ng/ml), coupled with low complement 3a des-arginine (<2368 ng/ml), almost universally (96%) developed the composite renal and mortality end point. C-reactive protein (adjusted hazard ratio, 1.4; 95% CI, 1.1 to 1.8), neutrophil gelatinase-associated lipocalin (adjusted hazard ratio, 2.8; 95% CI, 1.3 to 6.1) and complement 3a des-arginine (adjusted hazard ratio, 0.6; 95% CI, 0.4 to 0.96) independently predicted time to the composite end point.

Conclusions

Outpatients with the triad of high soluble TNF receptor-1 and neutrophil gelatinase-associated lipocalin coupled with low complement 3a des-arginine had high adverse event rates over 5-year follow-up. Incorporation of serum biomarkers alongside clinical variables improved prediction of CKD progression and mortality. Our findings require confirmation in larger, more diverse patient cohorts.
Trabajo docente en Vaca Muerta: condiciones, sentidos y tensiones desde zonas de sacrificio
Authors: Penas Ema Paula , Laurente María José
Published: May 2021

En la Norpatagonia argentina desde hace una década se despliega el megaproyecto de fracking Vaca Muerta. Aun cuando las profundas transformaciones territoriales atraviesan el campo educativo, la pregunta sobre qué implicancias tiene educar en estas zonas de sacrificio queda opacada frente a la hegemónica narrativa desarrollista. En base a los estudios sobre trabajo docente y políticas educativas, buscamos describir y comprender las principales condiciones, sentidos y tensiones que se manifiestan en el devenir del quehacer escolar, a partir de cómo sienten y piensan lxs docentes en este enclave petrolero de no convencionales. Desde la lógica cualitativa de la investigación es fundamental escuchar, documentar y analizar las voces de lxs docentes que realizan sus prácticas laborales en estos territorios. Los datos recogidos de entrevistas semiestructuradas se analizan a través del método comparativo constante. En virtud de los silenciamientos estratégicos, la “encerrona constante” y las múltiples tensiones que se producen en el trabajo docente en Vaca Muerta consideramos que —a tono con la dinámica del giro ecoterritorial— la construcción y la difusión de conocimientos sobre estas problemáticas son fundamentales para sensibilizar, problematizar y contribuir a los procesos de resistencia y alternativas al mal desarrollo en América Latina.
Regulating social spaces of everyday life
Authors: Chevalier Danielle
Published: May 2021

The utopian ideal of public space promotes it as the material manifestation of a freely accessible realm in which diverse social entities engage with one another to discuss, debate and form an inclusive society. In reality, access to and participation in public space is restricted for various factions of society. In the regulation of public space formal law plays a large, albeit not exclusive, role. Intrinsically formal law is presumed to come from above and beyond, and technically law is indeed emanated top-down by legislative authorities. The initiative to law however can originate from elsewhere. The case study presented here offers an example of law being enterprised from within, as a bottom-up strategy to claim dominance over a shared space and an attempt to block access to competing factions. Law then is wielded as a vertical power strategy between citizens, in which government has to struggle not to be reduced to an instrument in the hands of the elite. The case narrates the attempt of residents to have a municipal ban on using cannabis installed on a small inner-city playground in Amsterdam. This article aims to contribute to literature on juridification of social relations, the production of space and the making of law.
Marriage and divorce practices in Islamic centers in Italy
Authors: Alqawasmi Amal Yousef Omar
Published: May 2021

This paper studies Muslim marriages and divorces in Islamic centers in Italy, which are influenced by religion, and conducted outside the scope of Italian laws. The paper is basically empirical research, based on interviews with imāms in various Islamic centers, Muslim women and men who have chosen to refer to Islamic centers for their marriage or divorce, and family counselors following different cases. It investigates the motivations behind these practices by analyzing the fieldwork data, and demonstrates the related socio-legal consequences, specifically in relation to the role of Islamic centers and imāms in these marriages and divorces. The current state of religious rights for Muslims in Italy, and the lack of knowledge about the circumstances and reasons for these practices at national level are taken into consideration.
Green Corrosion Inhibitors to Head Off the Corrosion Rate of ST 37 Steels
Authors: Septiyani Arifin Devi Eka , Muliastri Destri , Rudiana Rudi , Sari Fitri Nur Indah
Published: May 2021

The corrosions process is a natural process and cannot be hindered, but it can be protected by adding a green inhibitor. Green corrosion inhibitors are a new alternative solution for corrosion protection because they are low-cost, biodegradable, and eco-friendly inhibitors. This research was used papaya leaves dan guava leaves extract as organic inhibitor solution by Maceration Method. The concentration of these green inhibitors is 0 mL, 1 mL, 2.5 mL, 3 mL, and 3.5 mL. The type of testing method used in this research is FTIR, PDP, and weight loss. The results show that there is Tanin function groups in papaya leaves and guava leaves extract.  The potentiodynamic polarization shows the value of corrosion rate without inhibitor is 0,418 mm/year. In contrast, the corrosion rate was decreased with improving the green inhibitor as many 3.5 mL. The corrosion rate was decreased until 0,00055 mm/year, and the value of efficiency is 99,868%.
The Influence of Service Quality, Price, and Brand Loyalty on Motorcycle Purchase Decision at Dealer CV. Andalas Motor Bengkalis
Authors: Asih Malika Nefti Budi , Maulana Hutomo Atman
Published: May 2021

This study aims to determine the effect of Service Quality, Price, and Brand Loyalty on Motorcycle Purchase Decisions at dealer CV.Andalas Motor Bengkalis. This research is associative research. The population used by consumers who buy motorbikes at dealer CV Andalas Motor Bengkalis with a sample size of 100 respondents. The technique used is multiple linear regression with the regression model Y=1.821 + 0.163X1 + 0.299X2 + 0.207X3 + e. The results of this study indicate that partially service quality has a positive and significant effect on purchasing decisions with tcount 2.466, price has a positive and significant effect on purchasing decisions with tcount 4.045. Brand loyalty has a positive and significant effect on purchasing decisions with tcount 6.158. Simultaneously, Service Quality, Price, and Brand Loyalty have a positive and significant effect on motorcycle purchasing decisions at dealer CV.Andalas Motor Bengkalis with Fcount 67.837 seen from the coefficient of determination 67.9%.
Resilience in institutionalized adolescents without parental care in the state of Morelos México
Authors: Gómez-Esquive Dulce Areli , Ortiz-Rodríguez María Araceli
Published: May 2021

Introduction. Resilience has been proposed as a novel research topic in environments with vulnerable populations, since it promotes healthy development in the face of adverse circumstances. In the case of adolescents without parental care, foster care in social institutions has been one of the resources most used by the State to offer protection and guarantee the human rights of girls, boys and adolescents in Mexico, who may or may not present a disability and who lack a father, mother or guardian, for which by means of these institutions they guarantee the healthy development of minors. Objective. Analyze the levels of resilience in institutionalized adolescents without parental care, with and without disabilities. Method. Analytical transversal. The Asylum Anomie and Nominal Resilience Inventory (IAAR) was applied. 29 adolescents (men) with an age range of 12 to 19 years participated, 24 without disabilities (SD) and 5 with disabilities (CD). Statistical analysis was performed using the SPSS v.25 program. Results. 17 adolescents (58.6%) presented resilience, 12 (41.3%) did not present resilience according to the IAAR. Conclusions. In our study, more than half of institutionalized adolescents show resilience according to the IAAR.
Evaluation of a workshop on social skills for professional practices in students of psychology and human communication therapy in the FPyTCH of the UJED
Authors: Lazcano-Franco Maura Antonia , Zamora-Ríos Rosa Angelica , Vázquez-Ríos Elda Raquel , Cejas-Leyva Luz María
Published: May 2021

Objective: To present the result obtained from the evaluation of a workshop on social skills for professional practices in students of Psychology and Human Communication Therapy within the Community Services Center at the Faculty of Psychology and Human Communication Therapy belonging to the Juárez University of the State of Durango. Methodology: Mixed in a sequential explanatory design (DEXPLIS), through the statistical analysis of a constant sample from the results obtained in the social skills scale tests (Gismero), EMES-C and EMES-M in three different moments using the IBM SPSS®, applying the bifactorial analysis of variance by ranges or Friedman's test. Contribution: Achieve a correct interpretation of the results from the established hypothesis, paying attention to the particularities of the professional work, seeking that the student of Psychology and Human Communication Therapy near to graduate has a repertoire of competent social skills, that contribute to efficient professional performance and personal fulfillment, as well as the development of positive attitudes and the reduction of emotional exhaustion.
Protocol design to assess the attention of children with Autism Spectrum disorder (ASD)
Authors: Ortiz-Simón José Luis , Hernández-Silva Gabriela Abigail , Aguilera-Hernandez Martha , Cruz-Hernández Nicolás
Published: May 2021

A correct assessment of the academic level of students with attention deficits is essential for any teacher and parent who is interested in integrating the student into a conventional education school. Centros de Atención Multiple (CAM) that care children with Autism Spectrum Disorder (ASD) do not always have the right way to evaluate a student with these characteristics. This work presents the design of a protocol for evaluating students presenting ASD by using simultaneously a mechanical pedaling system as an aid element to focus the student's attention on assigned tasks.
Application of Artificial Intelligence in the prediction of breast cancer survival in Mexican women
Authors: Melo-Morin Julia Patricia , Ahumada-Cervantes María de los Ángeles , Santana-Esparza Gil
Published: May 2021

In Mexico, the leading cause of death caused by malignant tumors in women is breast cancer and the general survival of five years treated in facilities of the Public Health System is between 75 and 80%. There are applications that determine the survival of patients with breast cancer, based on the use of drugs that are not prescribed in Mexico, so cancer specialists cannot consider the information offered by these programs for decision-making with patients Mexican. This article describes the development of an expert system that, by applying artificial intelligence techniques, allows the evaluation and prediction of patient survival, based on a model generated with data mining techniques. Rules were obtained from the patterns obtained with data collected from patients with breast cancer since 2006. The development of the system is governed by the Knowledge Discovery from Databases (KDD) methodology, supported by the WEKA tool for modeling data mining techniques. There is a data warehouse of 4,773 women with breast cancer provided by two tertiary hospitals in Mexico City: an INCan cohort of 4,300 patients diagnosed from 2006 to 2013 with a median follow-up of 40.5 months of survival and an INCMSZprovided cohort of 473 patients from 2011 to 2018 with a median of 39 months.
Sintaxis narrativa folklórica en Historia Apollonii Regis Tyri: estructura, personajes, tiempo y espacio
Authors:   , Trejo Malena Pilar
Published: May 2021

La presente investigación retoma las observaciones hechas hasta el momento sobre la relación de la novela con la narrativa folklórica. En particular, buscamos demostrar que la sintaxis narrativa de la novela Hist. Apoll. es folklórica. No queremos decir con esto que la novela sea un relato folklórico puesto por escrito, pues la evidencia textual no es suficiente para sostener esta tesis, sino que la tradición clásica que se hace presente en la novela se dispone sobre una base notoriamente similar a la de los relatos folklóricos. Acotamos nuestra lectura a cuatro elementos que consideramos troncales en el sistema de la narración: los personajes, el tiempo, el espacio y la estructura de la trama, que, como argumentamos, se desprende del análisis estructural de los personajes. Sostenemos que la particular disposición del tiempo en la narración y el diseño del espacio ponen en evidencia ciertos aspectos en general no advertidos del narrador que lo emparentan con los narradores de los relatos folklóricos. Para llevar adelante nuestra investigación, recurrimos a herramientas de la folklorística y de las narratologías estructural y cognitiva.
Romanian Auditors’ Perception Concerning the IT Impact in the Big Data Era
Authors: Cristea Lavinia Mihaela
Published: May 2021

Like any business process, auditing is a process that can be perfected, technology complementing a set of advanced data processing skills and techniques. The objective of this paper is to research the way how Romanian auditors work and perceive the impact of IT on audit missions. The results of the conducted survey, based on 102 responses, highlight a series of working tools (Data Analytics, Microsoft Excel, Data Automation) which, through the analysis of the Big Data phenomenon, facilitate the audit process. Regarding the software category, Ciel Audit and Revision, Gaudit, CaseWare are among the most frequently used, auditors considering ready to work with emerging technologies. Continuous professional training is ensured by participation in professional training courses, along with severe documentation about new technologies. In Romania, the current level of performing audits based on new technologies is average, for the future a higher level and a higher forecasting and analysis capacity are expected. The auditing profession will be perfected more and more, the current tasks will be gradually replaced by the new technologies, auditors becoming more appreciated by the external environment. Professional skepticism remains the basic quality of the auditor, along with the understanding of the competitive environment. Uncertainty characterizes the amendment of the International Standards on Auditing (ISA). This paper contributes to the literature by bringing to the fore the current technological context for the audit profession, namely the impact perceived by auditors during the fourth industrial revolution.
Hiteles és megbízható adatok a nemzeti adatvagyon szolgálatában
Authors: Pálmai Gergely , Csernyák Szabolcs , Erdélyi Zoltán
Published: May 2021

Az elemzés fókuszában az állt, hogy a nemzeti adatvagyonnal való hatékony gazdálkodást mennyiben támogatja a közadatok felhasználását érintő hazai szabályozási keretrendszer, valamint a nemzeti adatvagyon részét képező közadatok egyáltalán hitelesnek és megbízhatónak tekinthetők-e, ezáltal stabil támaszául szolgálnak, avagy sem, a közszféra digitalizációs és mesterségesintelligencia-alapú fejlesztéseit szolgáló törekvésekhez. Az elemzés bemutatja, hogy a nemzeti adatvagyon vonatkozásában miért bír kiemelt jelentőséggel a hiteles és megbízható adatok rendelkezésre állása. Ennek alátámasztásául ismerteti az adatvagyon felhasználásának különböző szintjeit, a mesterséges intelligencia alkalmazásának közszférabeli szerepét, valamint a közadatok hitelességének, illetve megbízhatóságának jelentőségét, kockázatait és kihívásait mind adatvédelmi, mind közpénzügyi szempontból. A bemeneti adatok pontatlansága, megbízhatatlansága ugyanis a megfelelő algoritmus alkalmazása esetén is predesztinálja a hibás eredménytermékek (következtetés, döntés) létrehozását, amely akár közvetlen anyagi kárt is okozhat, mind az állampolgárok, mind az állam számára. Az elemzés szerzői ezért felvetik, hogy paradigmaváltásra van szükség a közszféra adatainak hatékony felhasználását célzó stratégiákban, azon alapvető előfeltétel rögzítésének szükségességével, hogy a nemzeti adatvagyonnak megbízható és hiteles adatokon kell alapulnia.
Az informatika hatása a big data korszakban a román könyvvizsgálók megítélése alapján
Authors: Cristea Lavinia Mihaela
Published: May 2021

Mint minden üzleti folyamat, így a könyvvizsgálat is tökéletesíthető, mivel a fejlett adatfeldolgozási készségeket kiegészíti a technológia. A jelen cikkben a román könyvvizsgálók munkamódszereit vizsgáljuk, valamint azt, hogy szerintük milyen hatást gyakorol az informatika a könyvvizsgálói megbízások végrehajtására. A 102 résztvevővel végzett felmérés válaszai között többször előfordultak bizonyos módszerek és eszközök (adatelemzés, Microsoft Excel, adatautomatizálás), amelyek a big data elemzésével megkönnyítik a könyvvizsgálati folyamatot. A használatra kész, feltörekvő technológiák közül a leggyakrabban a Ciel Audit and Revision, a Gaudit és a CaseWare szoftvereket használják a könyvvizsgálók. Az új technológiákról szóló szakmai ismeretek folyamatos bővítését szakmai továbbképzések és átfogó dokumentációk biztosítják. Romániában az új technológiák alapján jelenleg átlagos szinten végeznek könyvvizsgálatokat, a jövőben magasabb szint, magasabb előrejelzési és elemzési kapacitás várható. A könyvvizsgálói szakmát egyre inkább tökéletesítik, a munkafolyamatba fokozatosan beépítik az új technológiákat. A külső környezet is jobban megbecsüli a könyvvizsgálókat, akik alapvetően továbbra is szakmai szkepticizmussal, valamint a versenykörnyezet ismeretével jellemezhetők. Bizonytalanság övezi a Nemzetközi Könyvvizsgálati Standardok (ISA) módosítását. A jelen cikk azáltal gazdagítja a szakirodalmat, hogy a könyvvizsgálói szakma jelenlegi technológiai környezetét helyezi előtérbe, nevezetesen a negyedik ipari forradalom során a könyvvizsgálók által észlelt hatásokat.
EVALUASI PELAYANAN VAKSIN COVID – 19 (STUDI KASUS PUSKESMAS MOJO KOTA SURABAYA)
Authors: Fadhilah Maharani Ulya , Fauziyah Umi , Cahyani Adellia Ammertia , Arif Lukman
Published: May 2021

During the COVID-19 pandemic, cases of the increase in positive patients in Indonesia were getting out of control and increasing in number, therefore the Government is ready for a vaccine that will be given in stages according to the priority of the recipient as an effort to tackle the spread of COVID-19 transmission. Vaccination can be carried out in health agencies such as in Puskesmas. The purpose of this research was to evaluate the quality of service in the implementation of the COVID-19 vaccination at Puskesmas Mojo Surabaya. The research method used is a qualitative approach with descriptive methods. The data technique used was observation, interview, and documentation study and then analyzed using an interactive data analysis model. The results of this study are the quality of the COVID-19 vaccination service at Puskesmas Mojo Surabaya based on the dimensions of public service Tangibles, Reliability, Responsiveness, Assurance, and Emphaty. Applicable in the process of vaccination services at Puskesmas Mojo Surabaya on complicated online data collection and scheduling, because not all of the facilities and population data are available where there have never been residents who have moved, therefore the result is a long queue to update the data. The quality of vaccine services at Puskesmas Mojo Surabaya is satisfactory in terms of facilities, services, and resources and it is necessary to make efforts to schedule and collect data more regularly to overcome service process constraints
Brain cell proliferation in adult rats after irradiation with nonequilibrium atmospheric pressure plasma
Authors: Yamato Masanori , Tamura Yasuhisa , Tanaka Hiromasa , Ishikawa Kenji , Ikehara Yuzuru , Hori Masaru , Kataoka Yosky
Published: May 2021

Nonequilibrium atmospheric pressure plasma (NEAPP) has the potential for a wide range of medical applications, including wound healing, blood coagulation, and malignant cell apoptosis. However, its effect on the mammalian central nervous system remains unclear. We studied histological changes in the cerebral cortex of adult rats, following irradiation of the brain surface with NEAPP. NEAPP irradiation made three laminar tissue structures and induced high proliferation of brain-resident immature cells as well as bone marrow-derived cells. These observations indicate that NEAPP irradiation induced rearrangement of cellular and tissue organization, including cell proliferation in the central nervous system in vivo.
Internal migration in Northern Ghana: understanding the integrative challenges of migrants in Tamale Metropolis
Authors:   Department of Planning, University for Development Studies, Tamale, Ghana, Mu-utasim Yahaya Muhammad
Published: May 2021

Purpose: Successful integration of migrants in any society has a very vital impact on the wellbeing of migrants. The study therefore uses descriptive statistics to analyse the integrative challenges of internal migrants in the Tamale metropolis of Northern Ghana. Research methodology: The study adopted the mixed-method approach and non-probability sampling techniques to select 120 internal migrants for the study. Results: The results revealed that economic factors (46.7%) accounted for most reasons cited for migrating. Language barriers (24.2%) and higher cost of living (19.2%) were the most encountered challenges and a proportion of 10.8 per cent reported not having encountered any difficulty. Limitations: The study explored all forms of internal migration in the Metropolis. However, it failed to explore the occurrence of international migration given the growing influx of international migrants in the study area. Contribution: The outcome of the study will advance knowledge on the challenges faced by migrants within the Metropolis and measures could be taken to resolve some undesired experiences. Additionally, the study will make a valuable contribution to the limited migration literature in the North.
LITERATURE REVIEW ON THEORIES MOTIVATION
Authors: Alex Acquah  , Takyi Kwabena Nsiah  , Elizabeth Naa Akushia Antie  , Benjamin Otoo
Published: May 2021

People possess something that machines don’t-human spirit and inspiration. It is the spirit and inspiration that leads associates to apply their human capital to meet the goals of the organization, the human spirit is highly inspired through motivation. Motivation is essential to almost any aspect of life. Understanding job satisfaction and work motivation can be key elements to improving productivity. This paper seeks to introduce the four major need theories areas: Maslow’s Hierarchy of Needs, Herzberg’s Motivation Theory, Alderfer’s ERG Theory, and McClelland’s Need for Achievement Theory. It also goes further to analyze these theories bringing to the fore various similarities and differences that exist amongst them.
ACCRUAL EARNINGS MANAGEMENT, REAL EARNINGS MANAGEMENT AND FIRM PERFORMANCE: A PANEL DATA ANALYSIS
Authors: Abraham Lincoln Ayisi  , Zhang Wenfang  , Joseph Adu-Gyamfi  , Agyemang Kwasi Sampene  , Ofori Charles
Published: May 2021

This research purposely looks into earnings management and how it relates to firm performance. By attempt of gaining empirical results, we proxy firm performance by return on assets (ROA)and return on equity (ROE) as dependent variables. We respectively model discretionary accruals and abnormal cash flow from operations as independent variables supported by firm size, leverage, and liquidity as control variables. Panel analysis was adopted to test a sample of 14 non-financial listed on the Ghana Stock Exchange from 2008 to 2019. We find that firms use both accrual earnings and real earnings methods to manage earnings. Results further indicate firms employ the efficient concept of earnings management to facilitate positive firm performance. Our analysis shows that companies with future acquisition prospects can use earnings management to boost financial efficiency. Although we find evidence of a positive relationship between EM and firm performance, we encourage authorities and facilitators to implement rules requiring transparent financial information to mitigate misleading results and reduce managers discretion. Prospective investors must also perform an in depth review of financial records prior to investing. Finally, our research has added to the body of expertise on earnings management, which positively impacts firm performance.
KEYWORDS: Earnings Management, Sales Manipulation, Ghana Stock Exchange, Firm Performance.
Administración del poder. Y crítica al pensamiento único en las “Ciencias Administrativas”.
Authors: Contreras Ricardo
Published: May 2021

Ante la crítica del Management como pensamiento dominante en las llamadas “Ciencias Administrativas”, falta un abordaje claro y profundo con las relaciones de poder que se da en la gestión. Las relaciones de poder en la administración tienen varias aristas que en consonancia se presentan de manera omnímoda, instrumental o en “corrientes exteriores” como fuerzas exógenas de coacción en el sistema capitalista mundial en las organizaciones. Por ello, es necesario, abordar el análisis de las relaciones de poder en la administración a un nivel  superior, integrador, transdisciplinario, político, social,  económico, cultural, ético y sostenible, para poder romper con la hegemonía del Management, y no quedar atrapado en el pensamiento único que él rige. El presente es un ensayo epistemológico crítico que aborda algunas aristas, ejes y tópicos de las relaciones de poder en cuanto a los temas sobre: la administración y la censura; la administración del poder y sus estructuras.
A survey on the stability of mean value points and functional equations involving some special functions
Authors:   DEPARTMENT OF MATHEMATICS PH. D. STUDENT, UNIVERSITY POLITEHNICA OF BUCHAREST SPLAIUL INDEPENDENT¸ EI 313, BUCHAREST, ROMANIA E-mail address: sorineldumitrescu@yahoo.com, DUMITRESCU SORINEL , MONEA MIHAI ,   DEPARTMENT OF MATHEMATICS PH. D. STUDENT, UNIVERSITY POLITEHNICA OF BUCHAREST SPLAIUL INDEPENDENT¸ EI 313, BUCHAREST, ROMANIA E-mail address: mihaimonea@yahoo.com, MORTICI CRISTINEL ,   DEPARTMENT OF MATHEMATICS VALAHIA UNIVERSITY OF TARGOVISTE BD. UNIRII 18, 130082 TARGOVISTE, ROMANIA,   DEPARTMENT OF MATHEMATICS ACADEMY OF THE ROMANIAN SCIENTISTS SPLAIUL INDEPENDENTEI 54, 050094 BUCHAREST, ROMANIA E-mail address: cristinel.mortici@hotmail.com
Published: May 2021

The aim of this work is to put together some of the recent and classical results in the theory of stability. In the first part, we recall the results regarding the intermediary points arising from various Mean Value Theorems, then we study the stability of some functional equations involving the gamma and beta functions.
Computing the Wiener index of graphs on triples
Authors:   DEPARTMENT OF MATHEMATICS AND TECHNOLOGY MAZANDARAN UNIVERSITY OF SCIENCE P.O. BOX 11111, BEHSHAHR, IRAN E-mail address: m ghorbani@iust.ac.ir, GHORBANI M.
Published: May 2021

Let S be a set of size n ≥ 8 and V be the set of all subsets of S of size 3. Three types of intersection graphs Gi(n), i = 0, 1, 2, can be defined with the vertex set V whose Wiener indices will be calculated in this paper.
k-Combinations of an unlabelled graph
Authors:   NATIONAL ORGANIZATION FOR DEVELOPMENT OF EXCEPTIONAL TALENTS (NODET) II AND I MASHHAD, IRAN DEPARTMENT OF PURE MATHEMATICS FERDOWSI UNIVERSITY OF MASHHAD P.O. BOX 1159, MASHHAD 91775 E-mail address: mrebrahimiv@gmail.com, VISHKI M. R. EBRAHIMI , MIRZAVAZIRI K. ,   NATIONAL ORGANIZATION FOR DEVELOPMENT OF EXCEPTIONAL TALENTS (NODET) II AND I MASHHAD, IRAN DEPARTMENT OF PURE MATHEMATICS FERDOWSI UNIVERSITY OF MASHHAD P.O. BOX 1159, MASHHAD 91775 E-mail address: mirzavaziri@gmail.com, MIRZAVAZIRI M. ,   NATIONAL ORGANIZATION FOR DEVELOPMENT OF EXCEPTIONAL TALENTS (NODET) II AND I MASHHAD, IRAN DEPARTMENT OF PURE MATHEMATICS FERDOWSI UNIVERSITY OF MASHHAD P.O. BOX 1159, MASHHAD 91775 E-mail address: mirzavaziri@um.ac.ir
Published: May 2021

In this paper we extend the notion of the binomial coefficient nk into a new notion [G/k], where [G] is an unlabelled graph with n vertices and 0 6 k 6 n. We call [G/k] as the graph binomial coefficient and a version of the graph binomial expansion is also studied. As an application of this notion, we enumerate the number of ways to color vertices of a path and beads of a necklace.
On decomposition of weak continuity
Authors:   DEPARTMENT OF MATHEMATICS WOMEN’S CHRISTIAN COLLEGE 6, GREEK CHURCH ROW, KOLKATA 700 026, INDIA E-mail address: bishwambhar roy@yahoo.co.in, ROY BISHWAMBHAR , SEN RITU ,   DEPARTMENT OF MATHEMATICS S. A. JAIPURIA COLLEGE 10, RAJA NABA KRISHNA STREET, KOLKATA 700 005, INDIA E-mail address: ritu sen29@yahoo.co.in
Published: May 2021

In this paper, the notions of locally µ-regular closed sets, µb-t-sets, µb-B-sets have been introduced. Using these concepts, the decomposition of some weak forms of continuity have been studied.
On some weak separation axioms
Authors:   DEPARTMENT OF MATHEMATICS COLLEGE OF SCIENCE QASSIM UNIVERSITY P. O. BOX 6644, BURAYDAH 51452, SAUDI ARABIA E-mail address: sabiriub@yahoo.com, HUSSAIN SABIR ,   sh.hussain@qu.edu.sa
Published: May 2021

We introduce and explore weak separation axioms namely γ-semi-Ti( for i = 0, 1, 2) spaces. We also define and discuss γ-semi-Di( for i = 0, 1, 2) spaces and develop the relations between these spaces. Moreover, we initiate the concept of γ-S-continuous function and discuss the behavior of γ-semi-D1 space under γ-S-continuous function.
Diameter Three Orientability of Bipartite Graphs
Authors: Chen Bin , Chang An
Published: May 2021

In 2019, Czabarka, Dankelmann and Székely showed that for every undirected graph of order $n$, the minimum degree threshold for diameter two orientability is $\frac{n}{2}+ \Theta(\ln n)$. In this paper, we consider bipartite graphs and give a sufficient condition in terms of the minimum degree for such graphs to have oriented diameter three. We in particular prove that for balanced bipartite graphs of order $n$, the minimum degree threshold for diameter three orientability is $\frac{n}{4}+\Theta(\ln n)$.
Testing through the Mann-Whitney Method and the Wilcoxon Signed Level on Learning Cube and Perfect Cube Roots
Authors: Susdarwono Endro Tri
Published: May 2021

The purpose of this study is to discuss the testing using the Mann-Whitney method and the Wilcoxon signaled level for learning perfect cube and cube root. This research is a quantitative study, while the method used is experimental. The quantitative approach used includes the Mann-Whitney test and Wilcoxon's signed rank test. The conclusions of this study are that: 1) for the Mann-Whitney test on the pretest value of the control group and the experimental group it is concluded that before the treatment of two groups, namely control and experiment, had the same ability in mastering the material to the third power and the cube root; 2) For the Mann-Whitney test on the post-test scores of the control group and the experimental group, it is concluded that after the treatment of two groups, namely the control and the experimental group, they have different abilities in mastery of the material in the third power and the cube root; whereas 3) for the Wilcoxon-signed level test on the pretest and posttest scores of the experimental group, it was concluded that there was a difference between the conditions before and after being given treatments on the mastery of the material to the third power and the perfect cube root.
GOVERNMENT SUPPORT FOR THE POPULATION AND BUSINESSES DURING THE PANDEMIC (THE CASE OF CHINA AND GERMANY)
Authors: Скворцова Татьяна Александровна , Рыбалко Павел Игоревич
Published: May 2021

Предметом данной статьи является анализ зарубежного законодательства (на примере Китая и Германии) в сфере оказания государственной поддержки населению и бизнесу в период распространения новой коронавирусной инфекции COVID-19. В исследовании анализируются правоотношения, связанные с поддержкой бизнеса, а также предоставлением пособий по временной нетрудоспособности, пособий по безработице, защите прав работников, выплате единовременных и ежемесячных сумм семьям, имеющим детей в период пандемии.

The subject of this article is the analysis of foreign legislation (on the example of China and Germany) in the field of providing state support to the population and business during the spread of the new coronavirus infection COVID-19. The study analyzes legal relations related to business support, as well as the provision of temporary disability benefits, unemployment benefits, protection of workers ' rights, payment of one-time and monthly amounts to families with children during the pandemic.
INNOVATIVE TECHNOLOGY OF A DISTILLATE FROM THE FRUITS OF CORNELIAN CHERRY
Authors: Небежев Кантемир Витальевич , Дубинина Елена Васильевна , Крикунова Людмила Николаевна , Трофимченко Владимир Александрович
Published: May 2021

Цель работы состояла в определении оптимальных технологических режимов и способов производства дистиллята из плодов культурного и дикорастущего кизила с учетом биохимических особенностей данного вида сырья. В результате были предложены новые технические решения, позволяющие получать высококачественный дистиллят из плодов кизила с использованием регулируемых процессов мацерации, сбраживания и дистилляции.

The aim of the work was to determine the optimal technological modes and methods of distillate production from the fruits of cultivated and wild cornelian cherry fruits, taking into account the biochemical characteristics of this type of raw material. As a result, new technical solutions were proposed to produce high-quality distillate from cornelian cherry fruits using regulated maceration, fermentation and distillation processes.
MINDFULNESS AS A NEW APPROACH TO SELF-REGULATION: PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL EFFECTS OF MINDFULNESS MEDITATION
Authors: Гайдукова Ольга Леонидовна
Published: May 2021

В статье раскрывается феномен медитации осознанности как инструмент психотерапевтических интервенций в отношении взрослых индивидов с нарушениями умственного развития (умственной отсталостью). Также рассматриваются некоторые наиболее распространенные техники данного подхода, чья эффективность применительно к данной группе популяции была доказана в приведенных в статье результатах экспериментальных исследований за последние годы.

The article describes the phenomenon of mindfulness meditation as a possible tool for psychotherapeutic interventions toward adult individuals with disorders of intellectual development (mental retardation). It also reviews some of the most common techniques of this approach, whose effectiveness for the considered group of the population has been proven by the results of experimental studies within recent years.
DRUG-INDUCED ITSENKO-CUSHING SYNDROME AS AN IMPORTANT PROBLEM OF MODERN MEDICINE
Authors: Власюк Ангелина Александровна , Федорцов Александр Александрович , Васильева Людмила Валентиновна , Малюков Дмитрий Андреевич
Published: May 2021

В данной статье представлена информация о медикаментозном синдроме Иценко-Кушинга, развивающегося у пациентов вследствие употребления глюкокортикойдов при различных заболеваниях, а также зависимость развития осложнений от методик получаемого лечения.

The article presents information about the Itsenko-Cushing drug syndrome, which develops in patients as a result of the use of glucocorticoids for various diseases, as well as the dependence of the development of complications on the received treatment methods.
THE IMPACT OF A COURSE OF THE AUTHOR'S METHOD OF VIBROACOUSTIC MASSAGE ON THE PSYCHO-EMOTIONAL STATE OF A PERSON
Authors: Огуй Виктор Олегович
Published: May 2021

В исследовании изучались изменения показателей психоэмоциальных характеристик в результате воздействия курсом виброакустического массажа поющими чашами (8-12 процедур ежедневно), выполненного по протоколу государственного патента на изобретение RU 2 687 006 C1. Автор и патентообладатель - Огуй Виктор Олегович. Полученные результаты свидетельствуют о том, что под воздействием виброакустического массажа поющими чашами, выполненного курсом из 8-12 процедур у испытуемых, значительно улучшаются психоэмоциональные характеристики. Кроме того, отмечалось статистически значимое снижение уровня депрессии, уменьшение уровня личностной и ситуативной тревожности. Представленный метод можно рекомендовать к использованию в санаторно-курортных и СПА-учреждениях.

The research studied changes in psycho-emotional characteristics as a result of exposure to a course of vibroacoustic massage with singing bowls (8-12 procedures daily), performed under the protocol of the state patent for invention RU 2 687 006 C1. Author and patentee - Oguy Viktor Olegovich. Conducting vibroacoustic massage according to the "singing bowls" method in a course of 8-12 sessions contributed to a significant improvement in the psycho-emotional characteristics of the subjects. In addition, there was a statistically significant decrease in the level of depression, a decrease in the level of personal and situational anxiety. The presented method is recommended for use in health resorts and SPA-institutions.