bluuebunny/crossref_metadata_2025 huggingface dataset:
Desempenho agronômico da cultivar de amendoim Granoleico em diferentes épocas de semeadura em Sorriso-MT
Authors: Olibone Ana Paula Encide , Olibone Dácio , Heuert Jair , Silva João Lucas Lopes , Xavier Maxuel Fellipe Nunes , Da Gama Timóteo
Published: November 2020

O objetivo deste estudo é determinar a melhor época de semeadura para cultivar de amendoim Granoleico nas condições de Sorriso-MT. O experimento foi realizado na área experimental do Instituto Federal de Educação, Ciência e Tecnologia – IFMT Campus Sorriso, localizado no município de Sorriso-MT. Foi utilizado o delineamento em blocos casualizados, com 3 repetições. Os tratamentos foram 6 épocas de semeadura (1ª - 07/11/2019, 2ª - 28/11/2019, 3ª - 19/12/2019, 4ª - 09/01/2020, 5ª - 30/01/2020 e 6ª - 13/02/2020). A cultivar de amendoim foi a Granoleico, desenvolvida pelo Criadero El Carmen da Argentina. As parcelas foram compostas por 4 linhas de 4 metros de comprimento e espaçamento de 0,90 m. As duas linhas centrais foram consideras como área útil, totalizando 7,2 m2 por parcela. Por ocasião da maturação das vagens, foram colhidas as plantas da área útil aos 140 dias após a emergência (DAE) para 1ª, 2ª, 3ª e 4ª épocas de semeadura, aos 117 DAE para 5ª época e ao 109 DAE a 6ª época de semeadura, pois as vagens estavam no devido ponto de maturação nas respectivas épocas. Foi determinado a produtividade de vagens (kg ha-1), rendimento de grãos (%), massa de 100 grãos (g), número de vagens por planta, número de grãos por planta e número de grãos por vagem. As variáveis número de vagens por planta, número de grãos por planta e massa de 100 grãos não obtiveram diferença significativa em função das épocas de semeadura da cultivar Granoleico. Somente a época 07 de novembro obteve o menor resultado de número de grãos por vagem em relação as demais épocas. Os melhores rendimentos foram obtidos nas épocas 09 de janeiro e 19 de dezembro. A época 07 de novembro resultou na maior produtividade de vagens. Por fim, constata-se a necessidade de outros estudos para obtenção da confirmação dos resultados obtidos nas condições de Sorriso-MT.
Rizobacterias Promotoras del Crecimiento Vegetal (PGPR) y sus efectos sobre la floración, ontogenia del grano y la granometría del cultivo de maní (Arachis hypogaea L.).
Authors: Bigatton Ezequiel Darío , Juárez Ricardo Javier Haro , Berdini Agustín , Baldessari Jorge Javier , Lucini Enrique Iván
Published: November 2020

Córdoba es la principal provincia productora de maní en Argentina con un promedio de 280-310 mil hectáreas sembradas por año. Las necesidades de incrementar los rendimientos y disminuir las presiones ambientales determinan la potencialidad de las Rizobacterias Promotoras del Crecimiento Vegetal (PGPR) como alternativa productiva. Las PGPR pueden estimular el crecimiento de los cultivos de forma directa o indirecta y, dentro de ellas se incluyen a los géneros Pseudomonas y Bacillus. La estimulación del cultivo por medio de las PGPR ocurre generalmente por producción de fito-hormonas y la solubilización de nutrientes que afectan entre otros parámetros la etapa reproductiva del cultivo y con ello la floración, formación de los frutos y rendimiento del cultivo. En este ensayo se utilizaron cepas nativas aisladas de suelos provenientes del cultivo de maní los géneros Pseudomonas y Bacillus, evaluando su efecto sobre la dinámica de floración, formación de vainas, ontogenia del grano, en un cultivar Granoleico tipo runner completando un ciclo de 150 días de siembra a cosecha. La cepa 002 de Bacillus spp. incremento la floración en relación con los controles y al resto de los tratamentos, traduciéndose en incrementos de la eficiencia reproductiva (+12%) y un aumento en el número de granos (+50%) de los calibres de granos de mayor diámetro (9-10 mm de diámetro medio de los granos). Pseudomonas spp. cepa 001 no alteró sustancialmente la eficiencia reproductiva (+1%), pero registró un incremento en la producción de granos relación al control (+45%).  Se sugiere que los cambios observados fueron consecuencia de los procesos de interacción planta-microorganismos donde las PGPR, mediante mecanismos de producción hormonal regulan los procesos de floración, la eficiencia reproductiva y la formación de los granos.
Dynamic Simulation on Canopy Light Distribution and Dry Matter Accumulation of Natural Colored Cotton in Alar Reclamation Area of Xinjiang
Authors:   College of Information Engineering, Tarim University, Alar, Xinjiang, China, Fan Zhenqi , Zhang Lixin
Published: November 2020

Based on Ross’s theory of optical radiation transmission and full consideration of influences of vertical distribution of canopy leaf area and leaf inclination angle distribution of colored cotton on the light distribution, the Gaussian 5-point distance was used to divide the canopy into 5 layers on basis of the leaf area index. The leaf inclination angle on each layer was divided into 6 equal parts by 15°. The types of radiation in canopy, spatial distribution of light radiation, as well as diurnal variation with solar hour angles were quantified in detail. After comprehensively considering influences of temperature, physiological age and other factors on photosynthesis and respiration, the canopy light distribution, photosynthetic production and dry matter accumulation of colored cotton were simulated with strong mechanistic and physiological & ecological significance. The colored cotton samples sown on April 16, 2019 were used to verify the model. The RMSEs of simulated and measured canopy PAR values at Beijing time 10:00, 12:00, 14:00 and 16:00 on July 30 were 58.2, 64.1, 43.4 and 39.7 µmol•m-2•s-1, respectively. The RMSE of simulated and observed values of the dry matter accumulation above ground was 412.6 kgDM•hm-2, reflecting the good predictability of the model.
Determination Optimal Indicators of Expressway Toll Plaza with M/G/1 Queue Model
Authors:   School of Mathematics and Statistics, Huizhou University, Huizhou, Guangdong 516007, China, Qiu Meilan , Li Dewang , Zhou Dazhuo
Published: November 2020

Long lines and heavy congestion is always the bottleneck problem of highway toll plaza, the operation efficiency of tollbooths is crucial to the traffic throughout of expressway toll plaza. In this report, we explore M/G/1 model in stochastic service system theory for obtaining the important indicators (eg: delay time, traffic throughput, construction cost and accident prevention) for improving the operation efficiency of tollbooths. Combining with fluid mechanics theory, we get the relationship between some important indicators such as queue length, delay time (including service time and overall waiting time) of the tollbooths system and the single channel capacity, and also the proportion of the number of various windows type. At the same time, we give out the reasonable accident coefficient and safety distance between vehicles. We find that the security distance between vehicles will directly affect the queue length, and thus influence the traffic capacity of toll booths.
Frequently-Used Properties of the Floor Function
Authors:   Department of Mechatronic Engineering, Foshan University, Foshan, China and State Key Laboratory of Information Security, Institute of Information Engineering, Chinese Academy of Sciences, Beijing 100093, China, Wang Xingbo
Published: November 2020

The paper collects 42 frequently-used properties of the floor function, including 35 ones from other literatures and 7 newly added-and-proved ones. The collected properties cover basic inequalities, basic identities, conditional inequalities, conditional equalities and practical formulas. The paper is helpful for scholars of mathematics and computer science and technology in reading and writing scientific works, reasoning and designing algorithms.
The Interaction of Five-Fingered Haptic Controller for Manipulating Object in Virtual Reality
Authors:   Dept. of Culture & Technology, Changwon National University, Changwon, Gyeongnam, South Korea, Nam SangHun , Lee Jiyong , Ko Ginam
Published: November 2020

In this paper, we designed a haptic controller interface that can control haptic controller with pressure sensors that collect pressure data from each finger, linear actuators to control different force feedback on each finger, and vibration motor. The haptic controller system consists of haptic controller hardware, haptic controller interface, and game engine module. The haptic controller hardware communicates with haptic controller interface module via serial communication. The game engine interface module performs physics-based interaction between haptic controller and virtual object. We designed the haptic controller interface with previously studied hardware and performed user tests. This paper showed the possibility of more realistic hand operation than the existing VR controller.
Development and Verification of Material Plasma Exposure Concepts
Authors: Pawar Dr. Avinash
Published: November 2020

The accessibility of future combination gadgets, for example, a Fusion Nuclear Science Facility incredibly relies upon long working lifetimes of plasma confronting segments in their diverters. Material-Plasma Exposure will use another high-force plasma source idea dependent RF innovation. This spring idea permit test to swathe the whole ordinary plasma surroundings in the diverter of a hope combination reactor. The option to examine disintegration and re-affidavit for pertinent calculations with applicable thrilling and attractive fields before the objective. Material-Plasma Exposure is being intended to take into consideration the presentation of from the earlier neutron-lighted examples. The objective exchange container has been intended to straight plasma generator with the end goal that it very well may be moved to posting for more itemized surface examination. Material-Plasma Exposure is being created in an arranged methodology with progressively expanded abilities. After the underlying improvement stride of the helicon source and the source idea is being tried in the Proto-Material-Plasma Exposure gadget. First warming with microwaves brought about a superior ionization spoke to by privileged electron solidity on pivot, when contrasted with the helicon plasma just without warming.
Use of Gyttja as Litter Material in Broiler Houses
Authors: FORT Gülümser , YETER Beyhan
Published: November 2020

The aim of the current experiment was to evaluate the possibility of the use of gyttja as an alternative litter material to pine wood shaving in broiler production. In the current experiment 3150 chicks were used in two experimental groups consisting of 1575 chicks with three repetitions (3x525 chicks). The experiment last for 39 days. During the experiment chicks in two experimental groups with same diets. There were no significant differences between experimental groups in terms of live weigth, feed consumption, feed conversion ratio and mortality. However, foot pad dermatitis (FPD) was found to be higher in the gyttja litter group and the difference between the groups was significant (P=0.011). In conclusion, gyttja could be used instead of pine wood shavings as litter in broiler houses without compromising the growth parameters. However, it should be known that there will be more FPD when using gyttja as litter in broiler production compared to using pine wood shavings.
Adição de lecitina de soja como adjuvante de secagem na obtenção de cajá em pó
Authors: Moura Neto Luis Gomes , Costa Janaina De Paula da , Soares Denise Josino , Silva Emanuel Marques da , Costa José Maria Correia da
Published: November 2020

Various drying techniques can be applied, depending on the raw material you want to dehydrate and what you want to obtain. One way to assess whether the dehydration method was efficient is through sorption isotherms. The objective of the work was to analyze and compare the adsorption isotherms of the cajá pulp powder obtained by atomization, with the use of maltodextrin (Test A) and maltodextrin and soy lecithin (Test B). The mathematical models of GAB, BET, Henderson and Oswin were used to represent the isotherms at 25, 30, 35 and 40 ° C. The results showed that the addition of lecithin gives a statistically different powder (p <0.05) from a powder without addition in relation to soluble solids, total sugars and its color. The BET model was the one that best fit Test A, and the Henderson model was the one that best fit Test B, which proved to be Type III in the J format. It was also observed that the addition of soy lecithin provided greater water adsorptio, which demonstrates that the product should be stored in a location with low levels of relative humidity or in packaging with low permeability.
An algorithm for measuring wind speed based on sampling aerosol inhomogeneities
Authors:   Research institute of radioelectronics and laser technologies of Bauman Moscow State Technical University, Filimonov P.A. , Belov M.L. ,   Research institute of radioelectronics and laser technologies of Bauman Moscow State Technical University, Ivanov S.E. ,   Research institute of radioelectronics and laser technologies of Bauman Moscow State Technical University, Gorodnichev V.A. ,   Research institute of radioelectronics and laser technologies of Bauman Moscow State Technical University, Fedotov Y.V. ,   Research institute of radioelectronics and laser technologies of Bauman Moscow State Technical University
Published: November 2020

A digital image processing algorithm based on sampling aerosol inhomogeneities was developed in the applied problem of laser remote sensing for measuring the velocity of wind. Tests of the developed algorithm were conducted for synthetic data from numerical simulations and data measured by a lidar. The algorithm developed performs processing of the field of aerosol backscattering coefficient in “Range-Time” coordinates and sufficiently increases the measurement accuracy in comparison with correlation methods.
Searching and describing objects in satellite images on the basis of modeling reasoning
Authors:   Kalashnikov Izhevsk State Technical University, Kasimov D.R.
Published: November 2020

The article presents an approach to a problem of contextual search and description of objects in raster satellite images, which consists in modeling reasoning on the basis of structured cases. As a result of image processing, an adjacency graph of color regions is constructed. The object is characterized by color, attributes of the form of segments of the border and the shape of the object as a whole. A structured case is represented in the form of a beam graph, whose arcs are ordered according to a positive bypass of the region boundaries. Using a graph matching algorithm, occurrences of cases stored in the system database are detected in the analyzed image. When the occurrence is detected, a case-based inference rule is applied. The degree to which an object belongs to a certain class depends not only on the properties of the object itself, but also on the reliability of the surrounding objects. The contextual search strategy contains stages of recursion and iteration. In contrast to neural network technologies, the proposed approach allows one not only to classify image objects, but also to form their structured descriptions. In addition, the classification decision issued by the system has a reasoned justification. The results of the experiment show that reasoning based on structured cases allows refining the results of classification and increasing the reliability of object recognition in satellite images.
An abstract model of an artificial immune network based on a classifier committee for biometric pattern recognition by the example of keystroke dynamics
Authors:   Omsk State Technical University, Sulavko A.E.
Published: November 2020

An abstract model of an artificial immune network (AIS) based on a classifier committee and robust learning algorithms (with and without a teacher) for classification problems, which are characterized by small volumes and low representativeness of training samples, are proposed. Evaluation of the effectiveness of the model and algorithms is carried out by the example of the authentication task using keyboard handwriting using 3 databases of biometric metrics. The AIS developed possesses emergence, memory, double plasticity, and stability of learning. Experiments have shown that AIS gives a smaller or comparable percentage of errors with a much smaller training sample than neural networks with certain architectures.
A method of wavefront distortions correction for an atmospheric optical link with a small volume of information transmitted through a service channel
Authors:   Volgograd State University, Nevzorov A.A. , Stankevich D.A. ,   Volgograd State University
Published: November 2020

The paper describes a method of wavefront distortion correction in a turbulent atmosphere, which allows reducing the volume of information transmitted through a service channel. The correction is carried out with a transparency whose phase mask is calculated by a simple three-layer neural network by intensity distribution obtained at the photoreceiver. The architecture of the network is constructed so that the amount of data transferred over the service channel is reduced to 30 parameters, using which a corrective mask is then constructed.
Seismogeological characteristics and oil-and-gas prospects of the cambrian sediments within the Vilyui hemisyneclise
Authors:   Institute of Petroleum Geology and Geophysics SB RAS, Gubin Igor A. , Kontorovich Alexey E. ,   Institute of Petroleum Geology and Geophysics SB RAS, Fomin Andrey M. ,   Institute of Petroleum Geology and Geophysics SB RAS
Published: November 2020

Based on geological and geophysical data, such as deep drilling, well logging, seismic surveys CDP-2D, DSS, SK-VSP a sedimentary cover structural model of the Vilyui hemisineclise to the lower Cambrian roof is constructed. According to seismic data interpretation, the ubiquitous development of the oil and gas source Kuonamka formation is predicted within the internal boundaries of the Vilyui hemisyneclise, where it formed an extensive center of hydrocarbon generation. Clinoform-built Middle Cambrian rocks (Maysky stage) overlie Kuonamka formation. The reservoirs development in the Maysky stage rocks is substantiated, a forecast map of porosity coefficients is generated.
Reflections on the Theory of the Contraction and Expansion of Religious Knowledge
Authors: Pashaei Mohammad Javad
Published: November 2020

The principle of the relationship between religious and non-religious knowledge is not hidden from anyone and it is obvious that without the help of sciences such as literature, logic, principles of jurisprudence, principles of understanding hadith and rijal, etc., a correct understanding of religion can not be achieved. Found. However, some consider this interaction to be maximal and refer to it as the theory of Contraction and Expansion of Sharia. This idea, which from the designer's point of view is delivered to the three pillars of description, explanation and recommendation, can be detailed into ten pillars with a little reflection. The author of this study, who has critiqued this theory with a descriptive analytical method, considered problems such as self-inclusion, sophistry, doubt in the existence of the essence of religion, lack of distinction between certain and doubtful knowledge, etc. as the most important is shortcomings of this theory.
Legal Protection of Patients Participants of Health Social Guarantee in Human Rights Perspective
Authors: Widjiastuti Agustin , Warka Made , Suhartono Slamet , Hufron Hufron
Published: November 2020

The rule of law through the government must provide public services for its people.  In the conception of the welfare law state, every citizen/every person has the right to obtain good services and obtain legal protection from arbitrary actions by the authorities. Based on Article 1 number 1 of Law Number 39 of 1999 concerning Human Rights, human rights are rights inherent in every human person that must be protected so that human rights are always the core material of a modern state constitution. Legal steps for patients participating in the Health Social Security Administering Body in the perspective of legal protection.
Performance Reviewed from Maqasyid Shariah, Culture of Islamic Organizations and Sharia Compliance
Authors: Faisal Yusuf , Sudibyo Yvonne Agustine
Published: November 2020

This examine objectives to decide the effect of Islamic maqasyid, Islamic organizational tradition and Sharia Compliance at the overall performance of sharia bank personnel. The pattern of this examine is 203 personnel of Islamic banks spread across three nation banks, specifically unbiased Islamic banks, Indonesian people's Islamic banks, Indonesian nation Islamic banks and Islamic muamalat banks which are the primary Islamic banks in Indonesia. The consequences of this examine indicate that the Islamic maqasyid has a poor and sizable impact at the overall performance of personnel, even as the Islamic organizational tradition and Sharia Compliance have a fine and sizable impact at the overall performance of personnel of Islamic banks.
The Education of Multi Religious Culture on Madrasah Aliyah: Study at Abu Hurairah Islamic Boarding School Mataram West Nusa Tenggara
Authors: Zainud Zainud , Hakim Lukmanul
Published: November 2020

Education in the Islamic boarding school not only emphasize on cognitive acquire, but also how to implement the values of that cognitive comprehension itself. Therefore, Islamic boarding school develops the religious culture to embody the positive behavior to students in their daily life through religious values. For this reason, this study aimed to find out the values of religious culture existed in Islamic boarding school. This study was a qualitative descriptive design.Observation, in-depth interviews, and document analysis were used to collect the data. The data were analyzed comprised of four components, namely 1) Data collection, 2) Data Reduction, 3) Data display, and 4) Data verifications or conclusion. The result of this study showed that; 1) The type of religious culture implemented at Abu Hurairah Islamic boarding school Mataram west Nusa Tenggara on Madrasah Aliyah (Senior High School) include; Smile and Greeting habituation, mutual respect, and tolerance, praying Dhuha, Praying Zuhur on the congregation, tadarrus Al-Qur’an (learning Al-Qur’an) / Tahfiz Al-Qur’an (memorizing of Al-Qur’an), 2) the implementation of Religious culture. Values in teaching and learning at Abu Hurairah Islamic boarding school Mataram west Nusa Tenggara on Madrasah Aliyah (Senior High School) through the activities of curricular, co-curricular, and extracurricular. The values of religious culture embodied by students included; the spirit in obeying rules of Islamic religion, the spirit of mutual help, the spirit of brotherhood, the spirit of sacrifice, spirit to love science, spirit for working hard, and spirit of tolerance. 3) The implication of embodiment values of the multi-religious culture at Islamic Boarding Schools was impacted to all Islamic Boarding Schools officials, especially to the students, they have good behavior, speak politely, always respect towards diversity, more active in social activity in the society, mutual help, more discipline, and more competitive in facing the social problem in society, and the graduates has ability to compete to be accepted in the State University or private university.
Business Model Innovation and Its Implications for Indonesian Batik’s Start-up Development
Authors: Wijaya Inthannia Elvaretha , Pangeran Perminas
Published: November 2020

Business Model Innovation is the key to develop and improve the company's strategy to survive and sustain. Nevertheless, the existing Batik communities often find it difficult to innovate their business model. The purpose of this study was to evaluate the nine components of the business model canvas, in Batik communities, Giriloyo and Kricak Kidul village, Yogyakarta. Second, develop an innovation on business model, Ruby Batik start-up. The evaluation research method used was descriptive qualitative case study approach. The data were collected through questionnaires and in-depth interviews. The analytical model used the CIPP (Context, Input, Process, Product). The results showed that nine components of the business model canvas of the batik communities, Giriloyo and Kricak Kidul, Yogyakarta were still less and need improvement and innovation. Innovation of the business model canvas component became the development basis of social entrepreneurship business model, Rubi Batik start-up. The startup business model development, Rubi Batik, was directed to the commercial mission and social impact mission.
Inflammation and cardiac insufficiency associated with infectious endocarditis
Authors: Fedorova T. A. , Tazina Serafima Ya. , Kaktursky L. V. , Kanareitseva T. D. , Stefanenko N. I. , Burtsev V. I. , Semenenko N. A.
Published: November 2020

The study included 62 patients with uncomplicated primary and secondary infectious endocarditis admitted to S.P. Botkin city hospital from 2011 to 2014. The emphasis is laid on diagnostic significance of dynamic measurements of the levels of C-reactive protein, tumour necrosis factor, and highly sensitive troponin-1 for the evaluation of activity of the infectious/toxic process, severity of the disease, and detection of complications. The study revealed the relationship of the enhanced level of troponin-1 with changes of inflammation markers, morphofunctional characteristics of myocardium, and circulatory failure. Morphologicl study demonstrated inflammatory and dystrophic changes in myocardium, focal and diffuse cardiofibrosis suggesting development ofnon-coronarogenic myocardial lesions that play an important role in the progress of cardiac failure associated with infectious endocarditis.
Systemic inflammation and compromised intestinal barrier during successful treatment of HIV infection
Authors: Shmagel' N. G. , Shmagel' Konstantin V. , Korolevskaya L. B. , Saidakova E. V. , Chereshnev V. A.
Published: November 2020

The relationship between immunity disorders, destruction of intestinal barrier, and development of systemic inflammation during antiviral therapy in patients with HIV infection is a topical issue in terms of suppression of virus replication and reduction of its role in the pathological process. Study object. Blood of HIV-infected patients given antiretroviral therapy (n=21) and non-infected volunteers (n=20). Methods. Identification of cells among CD4+ and CD8+ T-lymphocytes expressing markers of activation (CD38, HLA-DR), depletion (PD-1), and interleukin (IL) 7 receptor (CD127); measurement of blood levels of IL-6, neopterin, soluble CD14 (sCD14), intestinal fatty acid-binding peptide (I-FABP), and bacterial lipopolysaccharide. Correlation analysis of the dependence between cell immunity and systemic inflammation was performed. Results. HIV-infected patients had more activated CD4+ and CD8+ T-lymphocytes and CD4+ T-cells expressing PD-1 marker than non-infected subjects but less CD4+ and CD8+ T-lymphocytes expressing CD127. Blood IL-6, neopterin, soluble CD14, I-FABP, and bacterial lipopolysaccharide levels in the former were higher than in the latter. HIV-infected patients showed significant correlation of cell immunity parameters with blood neopterin and FABP levels. Conclusion. The process of activation, depletion, and regeneration of T-lymphocytes in HIV infection are related to the destruction of intestinal barrier and systemic macrophage activation.
Anticoagulants today
Authors: Bokarev Igor N.
Published: November 2020

A review of modern concepts of clinical application of anti-thrombotic drugs, such as heparins, antivitamins K, oral anticoagulants, and thrombolytics is presented.
The surgeon V.I. Gedroits, a disciple of Cesare Roux, a Lausanne surgeon. Part I
Authors: Blokhina Nataliya N.
Published: November 2020

The paper overviews personality formation of the woman surgeon Vera Ignat’evna Gedroits (1870-1932), a follower of the world-famous Cesare Roux of Lausanne.
Prospects for the clinical application of statins in gastroenterology
Authors: Svistunov A. A. , Osadchuk M. A. , Kireeva Natalia V.
Published: November 2020

We present the analytical review of non-cardial effects of statins used in gastroenterology with the data illustrating their high antibacterial activity as exemplified by combined therapy of conditions associated with Helicobacter pylori infection. Special emphasis is laid on anti-inflammatory and oncoprotective mechanisms of statin action that are successfully made use offor the treatment of liver, pancreas, gallbladder, and biliary system diseases. Prophylactic aspects of statin application to overcome an addiction to fast food are discussed.
Contribution of lipoprotein(a) to cardiovascular risk in patients under 40 years of age after acute myocardial infarction or acute cerebral circulation disorder
Authors: Korneva Viktoriya A. , Kuznetsova T. Yu. , Novitskaya A. S. , Malygin A. N. , Guseva T. A. , Ukhanova E. A.
Published: November 2020

Aim. To evaluate the importance of lipoprotein(a) for the evaluation of cardiovascular risk in patient under 40 years of age after acute myocardial infarction or acute cerebral circulation disorder. Materials and methods. We analysed the data from two departments of the Regional Vascular Centre for 2013-2015 including 90 case histories of patients of different age (mean 57.8±3.4 yr) and studied standard risk factors, such as age, sex, smoking habits, dyslipidemia, aggravated heredity, arterial hypertension (AH), obesity. Standard examination of 7 patients under 40 years of age was supplemented by measuring lipoprotein(a) by the immunoturbodimetric method regarding the levels over J. 3 g/l as abnormally elevated. Results. The study group was dominated by young and middle-aged men (85.2 and 84% respectively). The key riskfactors were increased LDLP level (88%) and smoking (70%) in patients under the age of 40 and AH in middle-aged men (100%, p<0.004). Arterial hypertension was also diagnosed in 59% of the younger subjects. Increased LDLP levels most frequently occurred in senior patients (90%). The group ofpatients under 40 yr included 15% of those having a single risk factor. In this group, 22% of the patients were at high risk calculated prior to the development of vascular events, 58% at moderate and 20% at low risk. 42.8% of the patients had elevated lipoprotein(a) levels. Conclusion. Based on the relative risk scoring scale, 22% of the patients under 40 years of age were at risk of myocardial infarction or cerebral circulation disorders prior to the development of vascular events. However, these patients like those of other age groups frequently had traditional riskfactors, such as smoking (67.5%), AH and dyslipidemia (66.6% each). Total cholesterol was elevated only in 47.6% of the patients while LDLP and LP(a) in 92 and 42.8% respectively.
Development of early metabolic and vascular disorders in young subjects
Authors: Vasil’eva E. M. , Nikitin Anatoly V. , Bulat A. A. , Zhemchuzhnikov S. V.
Published: November 2020

Deterioration of health characteristics and ever increasing diabetes and cardiovascular morbidity among young subjects imply the necessity of identification ofpossible risk factors of these conditions. We evaluated the prevalence of hyperlipoproteinemia and adipose tissue activity based on the results of screening for resistin level, aggravated heredity, disordered hydrocarbon metabolism, overweight, arterial hypertension, behaviour (physical overstrain, hypokinesia, smoking, inadequate dietary regime). The risk of developing type 2 diabetes mellitus and overall risk of cardiovascular disorders were calculated.
Community-acquired pneumonia in pregnancy
Authors: Sinopal’nikov Alexander I. , Styrt E. A.
Published: November 2020

A brief review of modern data on etiology, pathogenesis, diagnostics, antibacterial therapy, and vaccine prophylaxis of community-acquired pneumonia in pregnancy is presented.
The cardiovascular system in type 2 diabetes mellitus and thyroid disorders in the absence of thyroid gland dysfunction
Authors: Ballyuzek Marina F. , Ignat’eva P. A.
Published: November 2020

The state of the cardiovascular system was studied in patients with type 2 diabetes mellitus and thyroid disorders in the absence of thyroid gland dysfunction. 76.9% of the 302 patients with DM2 had thyroid pathology; in 23,8% it was not previously diagnosed. We compared euthyroid patients with DM2 without thyropathies and with diffuse-nodular changes largely in the form of diffuse-multinodular non-toxic goiter and autoimmune thyroiditis (AIT). It was demonstrated that enhanced frequency of thyroid disorders is related to DM2 duration and vascular complications. The predominant thyroid pathology in DM2 was diffuse-multinodular non-toxic goiter followed by autoimmune thyroiditis. Nodular forms in AIT without DM2 are rare whereas multinodular forms in the patients with DM2 and AIT occur much more frequently. Node formation is related to such DM2 complications as diabetic nephropathy, angiopathy, and retinopathy. The study showed that the frequency of both non-specific clinical changes characteristic of thyroid dysfunction and of specific cardiological manifestations in euthyroid patients with DM2 and thyroid pathology significantly increases especially in the presence of AIT and anti-thyreoperoxidase antibodies, regardless the form of thyropathy. It may be due to immuno-inflammatory cross talk between thyroid and myocardial tissues. Patients with DM2 and diffuse-nodular changes in the thyroid gland more frequently presented with different forms of atrial fibrillation and high-grade ventricular extrasystole than patients with AIT or DM2 without thyropathies. It is concluded that euthyroid patients with DM2 need their thyroid function to be regularly monitored. The development of examination algorithm is an object of further studies.
The strategy for the surgical treatment of femoral fractures in polytrauma
Authors: Shapkin Yu. G. , Seliverstov Pavel A.
Published: November 2020

The review describes peculiarities of the choice of time and methods of osteosynthesis offemur fractures of different localization in patients with multiple injuries in accordance with modern concepts of treatment of severe multiple and associated lesions. Analysis of domestic and foreign literature shows that earlyfixation of the femur in case of polytrauma can reduce the mortality rate associated with complications and improve the functional outcome. Terms of osteosynthesis of the femur in polytrauma should be chosen taking into account the severity of the injury, the patient's condition, and the period of traumatic disease. The procedure of osteosynthesis must not be a threat to the clinical condition. The choice of the method for fixation of the femur depends of fracture type and location, the presence of fractures in the adjacent and remote segments. The minimally invasive techniques of osteosynthesis of the femur and staged surgical treatment of the victims in an unstable state should be chosen for the treatment of multiple injury in accordance with the concept of «Damage Control Orthopedics».
Clinical rhetoric in the high school
Authors: Odin Vitaly I.
Published: November 2020

Clinical rhetoric is a science concerned with consistent patterns of speech behavior in different situations of interaction with colleagues, patients, and specialists in various disciplines with a view to extending their practical applications for the enhancement of efficiency of meaningful contacts. The history of this science as a means of rational communication with patients and medical profession dates back to the times of Hippocrates. Its importance greatly increased under the present-day conditions of high-technology and therapeutically aggressive medicine. Clinical rhetoric is based on the principles of general rhetoric. A clinician must be prepared for he fruitful and constructive relations with a variety of partners including patients, healthy subjects, administrators, lawyers, businessmen, and colleagues. Four main peculiarities of clinical rhetoric are distinguished: any debate is possible only in the form of discussion, both the form and content of the opponent’s arguments should be treated with respect, the speaker must himself draw attention to the weak points of his theses, all discussions must have the form of a “captain council” in which the shipboy is the first and the captain the last to speak. Traditional forms of clinical discussion include counselling, doctor’s rounds, consilia, and demonstrations. Collective forms of stimulating creative thinking, such as brainstorming and foresight have especially good prospects. These approaches appear to be of special value for the solution of heuristic problems. Teaching clinical rhetoric should be initiated since term IV when students begin to understand the role of a doctor as a key figure in the organization of the diagnostic and therapeutic process. Further development of Hippocrates’ traditions of collective communication may significantly promote the intellectual return from clinical and scientific discussions in medicine.
Pathogenetically targeted method for conservative treatment of obesity and overweight correction
Authors: Achkasov Evgeniy E. , Razina A. O. , Runenko S. D.
Published: November 2020

This review of literature presents modern pathogenetic treatment options for obesity and overweight correction including the optimization of the motor function, nutrition education, drug therapy, surgical techniques and psychotherapy. The need for a multidisciplinary approach to the development of combined treatment programs is underlined taking into account the multifactorial pathogenesis of obesity. A combination of optimal physical activity and diet therapy with active personal involvement in the process of recovery is accentuated among the priority areas of excess body weight correction, as well as the treatment and prevention of obesity. It is shown that the physical rehabilitation should focus on the individualization of the physical exertion, its adequate dosing and intensity control using heart rate monitors to ensure the safety and effectiveness of the training sessions. The article also presents data on the effectiveness of rational medical and other types of treatment of obesity when the adjustment of physical activities and nutrition is insufficient. In particular, the results of the world's largest observation program of safe weight loss for the treatment ofpatients with alimentary obesity held in Russia from 2012 to 2015 are described.
Unresolved problems of the evaluation of myocardial blood supply
Authors: Milyukov V. E. , Zharikova Tat’yana S.
Published: November 2020

Over the past few decades, a steady rise in the incidence, morbidity and mortality from cardiovascular diseases has been observed throughout the world. The most common pathology is coronary heart disease (CHD) which, in addition, is responsible for chronic heart failure in more than one third of the cases. Patients with coronary heart disease are in need of early diagnosis and timely treatment. This article provides an overview of current scientific literature concerning anatomy of coronary vessels, their age-related changes, and modern radiological diagnostic methods of the lesions associated with coronary artery disease.
Venous ectasia of gastric antrum
Authors: Olevskaya Elena R. , Tarasov A. N.
Published: November 2020

Gastyic antyal vasculay ectasia (GAVE) is an uncommon but often seveye cause of uppey gastyointestinal bleeding. GAVE may be asymptomatic oy accompanied by clinical anemia oy oveyt gastyointestinal bleeding. The diagnosis is mainly based on pathognomonic endoscopic patteyn, defined as «wateymelon stomach», located in antyum. Autoimmune disoydeys aye co-existing in about 60% of patients with GAVE, chiyyosis in about 30%, and caydiac oy yenalfailuye in 10%.The "golden standayden" tyeatment of GAVE is endoscopic aygon plasma coagulation (APC). Theye is pooy infoymation about diagnostics and tyeatment of GAVE in the domestic liteyatuye. The analysis of the pyesented mateyials shows that coyyect diagnostics takes much time and the choice of the optimum optimal tyeatment styategy encounteys difficulty. Ouy expeyience with diagnostics and theyapy of GAVE is based on the tyeatment of 4 patients. The diagnosis of GAVE was established within the peyiod fyom 5 months to 1.5 yeays aftey onset of the disease. In two cases, GAVE was asymptomatic. Two patients with seveye anemia completed endoscopic tyeatment; in one case, APC was supplemented by lasey coagulation and bipolay coagulation. The implementation of lasey coagulation caused some technical difficulties. Tyeatment of both patients was successful. Endoscopy pivotal foy diagnosis of GAVE is the main method of its tyeatment. Due to the layge numbey of diagnostic eyyoys and the impoytance of coyyect diagnosis of GAVE, it is necessayy to pay attention to this issue in tyaining pyogyams foy endoscopists.
E.O. Mukhin - an outstanding Russian anatomist and clinician (on the occasion of his 250th birthday anniversary)
Authors: Bakhmet Anastasiya A. , Klochkova S. V. , Sheptulin D. A.
Published: November 2020

Efim Osipovich Mukhin is an outstanding yepyesentative of Russian medical science who made an impoytant contyibution to the development of anatomo-physiological studies, establishment of suygeyy and tyaumatology as independent medical disciplines in this countyy, intyoduction of smallpox vaccination and aseptics into clinical pyactice as well as to the impyovement of teaching medicine at univeysities.
Criteria for granting permission for disabled persons to participate in the Ready for Labor and Defense training program
Authors: Mashkovsky Evgeny V. , Predatko K. A. , Magomedova A. U. , Shteinerdt S. V. , Volodina K. A.
Published: November 2020

Rehabilitation, adaptation, and social integration of the disabled are the priority issues of social welfare policy in the Russian Federation. This includes the enhancement of availability ofphysical education and adapted sports programs. One of the best practices for the improvement ofphysical activity among the population is the "Ready for labour and defense" training system (GTO). However, it is not adapted for those with physical challenges and disabilities. To involve this special fraction of the population in physical activity and participation in the GTO system, disability groups eligible for this activity need to be identified. They can include individuals with visual (VI), intellectual (II), hearing (HI), and locomotor problems as well as those with transplanted organs (TO). Also, minimum disability criteria (MDC) for the participants from each group which would make them eligible to practice an adapted GTO system should be defined. The development of MDC for individuals with VI, II, HI, and TO is relatively easy as they are common for most adapted sports. However, it remains a challenge for persons with locomotor problems since they make up a very diverse group bearing in mind that the rules of the International Paralympic Committee envisage different MDC for different adapted sports. There are two possible solutions: (1) to develop specialized MDC for each sport discipline included in the GTO system, (2) to develop universal MDC for all disciplines. The next step in promoting the GTO system among individuals with physical challenges and disabilities will be the development of the para- GTO program that would be unique and adapted for all categories of the disabled individuals.
Monitoring plasma imatinib level to improve results of therapy of chronic myeloid leukosis
Authors: Savel’eva Marina I. , Kryukov A. V.
Published: November 2020

The achievement of early cytogenetic and molecular responses is the major objective of therapy and a main prerequisite for the favourable long-term outcome of the disease. The maintenance of dose intensity and management of adverse events are keys to successful treatment of chronic myeloid leukemia (CML) with imatinib. Therapeutic monitoring and testing the drug level in blood are the efficient tools for the treatment ofpatients with CML and can be usedfor analysis of treatment failure or suboptimal response to therapy, suspected noncompliance, drug interactions or unexpected adverse reactions.
Prevalence and typological characteristics of atherosclerotic lesions in carotid arteries associated with metabolic syndrome as revealed by multislice computed tomography
Authors: Praskurnichiy Evgeniy A. , Aleksandrova I. I. , Kostycheva T. V. , Knyazev A. N.
Published: November 2020

Aim. To study the character, prevalence, and typological structure of atherosclerotic changes in major arteries by multislice computed tomography in patients with various metabolic disorders. Material and Methods: Carotid arteries of 78 patients with metabolic syndrome or type 2 diabetes mellitus and without carbohydrate metabolism disorders were examined by multislice computed tomography. Results: The study revealed various types of atherosclerotic plaques differing in the composition of lipid, lipid-fibrotic and calcium components. The latter were especially well expressed in diabetes. Conclusion. All types of atherosclerotic plaques are roughly equally represented in the structure of atherosclerotic lesions of carotid arteries in patients with metabolic syndrome in the absence of type 2 diabetes. Diabetic patients had vascular lesions with especially high density of atherosclerotic plaques.
"HELICARB" - the first Russian breath test kit with 99 % 13C-urea for Helicobacter pylori: from idea to registration
Authors: Plavnik Roman G. , Rapoport S. I. , Plavnik K. R. , Elman A. R. , Nevmerzhickij V. I.
Published: November 2020

The present study was aimed to develop and introduce in medical practice the first Russian kit for the C-urea breath test of Helicobacter pylori. The newly created kit was given the commercial name «HELICARB» and successfully passed technical, toxicological, clinical, and laboratory testing. The optimal dose of 13C-urea was determined and various devices needed to perform the test were compared. The results were approved by the Federal Service for Supervision in the health sector Roszdravnadzor) that issued the Registration certificate № RZN 2016/3773 (order № 1641 of 02.29.2016), which gives the right to manufacture and use the «HELICARB» test kit at the territory of the Russian Federation.
Three pinnacles in the course of
development of faculty therapy clinic of the Emperor Moscow University
Authors: Borodulin V. I. , Pashkov K. A. , Poddubny Mikhail V. , Topolyansky A. V. , Shadrin P. V.
Published: November 2020

The article highlights the history of the faculty therapy clinic of the Emperor Moscow University, i.e. of pre-Soviet MGU. The clinic’s activities are traced at their different stages when they were guided by profs. A.I. Over, G.A. Zakhar’in, P.M. Popov, V.D. Shervinsky, L.E. Golubinin, and N.F. Golubov. Analysis of numerous literature and archival data (including state archives and Shervinsky’s personal archive) provided a deeper insight into the post-Zakhar’in activities, allowed to correct erroneous information contained in some literature publications, and collect additional data for biographies of the leading professors of the clinic with special reference to the contribution made by the Shervinsky-Golubinin scientific and clinical school.Three pinnacles in the course of development of the clinic were distinguished dated to the mid-XIX century (under prof. A.I. Overt), the 1860s-1870s (under the then young reformer G.A.Zakhar’in), and the first decade of the XX century (under profs. V.D. Shervinsky and L.E. Golubinin who created a scientific therapeutic school that greatly promoted the further development of internal medicine in this country).
Rome criteria IV – irritable bowel syndrome (2016): what's new?
Authors: Svistunov A. A. , Osadchuk Michael A. , Osadchuk A. M. , Butorova L. I.
Published: November 2020

The report provides a critical analysis of the provisions of the Rome Consensus IV, related to irritable bowel syndrome. The comparative characteristic differences between the Roman criteria I, II, III and IV, relating to basic requirements for the diagnosis and treatment of this disease and try to bring them into the process of evolution to the basic requirements of evidence-based medicine.