bluuebunny/crossref_metadata_2025 huggingface dataset:
Overexpression of PD-L1 in Papillary Carcinoma and Its Association with Clinicopathological Variables
Authors: KOCAÖZ Servet , TURAN Gülay
Published: November 2021

Aim: Standard treatment may not be sufficient in patients with metastatic papillary thyroid cancer (PTC), and it may be beneficial to add PD-1 agents to the treatment. Therefore, this study was conducted to compare and evaluate the expression of PD-L1 in patients with nodular goiter (NG) and Hashimoto's thyroiditis (HT) within the scope of PTC carcinoma.
Material and Methods: Thirty-five patients from each group who underwent thyroidectomy for NG, HT, and PTC, between January 2011 and December 2017 were identified. Immunohistochemically, an anti-PD-L1 stain was applied by taking new sections from the tissue samples of 105 patients. The histological type, tumour diameter, capsule invasion (CI), and lymphovascular invasion (LVI) were evaluated.
Results: Nine (25.7%) of the patients with PTC were defined as classic, 10 (28.6%) as follicular, 6 (17.1%) as oncocytic, 5 (14.3%) as encapsulated, 2 (5.7%) as solid, 1 (2.9%) tall cell, and 2 (5.7%) as Warthin-like. The expression of PD-L1 in the patients with PTC was significantly higher than in the patients with NG and HT (p<0.001). There was a significant relationship between the increased PD-L1 expression and staining intensity and presence of thyroid LVI in the patients with PTC (p=0.047). In addition, the PD-L1 expression and LVI were observed to be more severe in patients with follicular, tall cell, and oncocytic subtype PTC (p=0.011, p=0.026, respectively).
Conclusion: It was observed that the PD-L1 expression increased in patients with PTC. PD-L1 expression and LVI were more severe in patients with follicular, tall cell, and oncocytic subtype of PTC.
МИНЕРАЛОГО-ГЕОХИМИЧЕСКИЕ ОСОБЕННОСТИ ПОЧВЕННОГО ПОКРОВА ЗОЛОТОРУДНОГО МЕСТОРОЖДЕНИЯ ВЬЮН (РЕСПУБЛИКА САХА (ЯКУТИЯ))
Authors: Мишанькин Андрей Юрьевич , Язиков Егор Григорьевич , Филимоненко Екатерина Анатольевна , Собянин Юрий Петрович
Published: November 2021

Ссылка для цитирования:  Минералого-геохимические особенности почвенного покрова золоторудного месторождения Вьюн (Республика Саха (Якутия)) /  А.Ю. Мишанькин, Е.Г. Язиков, Е.А. Филимоненко, Ю.П. Собянин // Известия Томского политехнического университета. Инжиниринг георесурсов. – 2021. – Т. 332. – № 11. – С. 98-109

Актуальность исследования обусловлена необходимостью получения данных о фоновом состоянии почв территории золоторудного объекта, а также целесообразностью поиска взаимосвязей между минеральными и геохимическими особенностями почвенного покрова месторождения. Цель: выявление минералого-геохимических особенностей почвенного покрова территории золоторудного месторождения Вьюн на доэксплуатационной стадии его освоения.Объект: почвы территории золоторудного месторождения Вьюн. Фактические материалы и методы исследования. Фактический материал получен сотрудниками кафедры геоэкологии и геохимии Национального исследовательского Томского политехнического университета в 2017 г. в ходе выполнения научно-исследовательских работ. В данной статье обсуждаются результаты исследований территории золоторудного месторождения Вьюн по данным изучения 19 проб почв. Работы проводились по стандартным методикам в соответствии с нормативными документами. Элементный состав почв устанавливался методом масс-спектрометрии с индуктивно связанной плазмой на содержание 55 химических элементов в аккредитованном химико-аналитическом центре «Плазма» (г. Томск). Минеральный состав почв определялся с помощью методов оптической микроскопии, рентгеновской дифрактометрии и сканирующей электронной микроскопии на базе Международного научно-образовательного центра «Урановая геология». Результаты обрабатывались с помощью современного программного обеспечения (Microsoft Excel, Statistica, Corel Draw и т. д.). Результаты. Выявлены минералого-геохимические особенности почв территории золоторудного месторождения Вьюн. Установлена взаимосвязь между минеральным составом рудной зоны и геохимической спецификой почв. Получены данные по повышенным содержаниям золота и элементов-спутников малосульфидного золотокварцевого оруденения, а именно мышьяка, серебра, сурьмы, определены их контрастные ореолы рассеяния, что может использоваться в практике дальнейших поисковых работ.
Fronteras Brasil y Perú, espacio de integración y cooperación
Authors: Laurente Itala , Filippi Eduardo Ernesto
Published: November 2021

Las fronteras son espacios donde se condensan las relaciones entre la población local y los diferentes niveles de gobierno, sea nacional o subnacional. Por eso, es relevante la creación de áreas fronterizas de paz y desarrollo sustentable, con base en la cohesión regional, integración social y territorialidad, lo que contribuye a la disminución de las tensiones entre los países y consolida los procesos de integración y cooperación continua. Particularmente, las fronteras de Brasil y Perú tienen una relevancia estratégica a razón de la biodiversidad, ubicación geográfica, presencia de lagos y ríos y porque es un espacio para el desarrollo económico de las fronteras. El motivo para desarrollar este artículo es, a razón de que en Brasil y Perú se desenvuelve una serie de dinámicas fronterizas sean territoriales, sociales, comerciales y económicas.El artículo tiene por objetivo analizar las regiones limítrofes entre Perú y Brasil como un espacio con características distintivas, lo que coadyuva a determinar posibles acciones futuras en la integración fronteriza. El estudio es descriptivo, de abordaje cualitativo basado en la revisión documental y cuantitativa de fuentes de secundarias. Se concluye en la necesidad de usar estrategias políticas, económicas, sociales pensadas de abajo-arriba que incorpore a diferentes actores multinivel, así como fortalecer los proyectos ya existentes que permitan la fluidez del comercio y mercado de productos tanto peruanos como brasileños a través de las fronteras, finalmente, reforzar la integración y cooperación entre fronteras para combatir actividades ilícitas y el mejoramiento del desarrollo de esas regiones.
Fragilidad del futuro: fenomenología de la vejez
Authors: Venebra Marcela
Published: November 2021

La tesis central de este artículo es que la vejez no se confunde con la enfermedad, y que su distinción arraiga en la dimensión temporal del cuerpo vivido. El tiempo del cuerpo es elemento ingrediente de la autocaptación (autoconstitución) del sí mismo en el horizonte de sus posibilidades y potencialidades, que en la vejez aparecen bajo una condición frágil y desgastada. Expongo esta tesis en tres partes principales: en la primera trato de deslindar las dimensiones del tiempo de la naturaleza y el tiempo subjetivo en el decurso constitutivo del cuerpo propio. En estas distinciones la vejez se esclarece, respecto del tiempo de la naturaleza, como la fase de cumplimiento normal o del más amplio y unitario desarrollo del cuerpo como cosa viviente. En la segunda parte, defino la fragilidad de futuro como especificidad estructural del horizonte temporal de la vejez; finalmente, en la tercera y última parte, exploro la incidencia de esta condición temporal en la forma de autocaptación (o auto-constitución) del yo, y en la significación (historización) de su propio cuerpo en la vejez. El marco metodológico de este estudio está centralmente tomado de los análisis husserlianos de la constitución en Ideas II.
O caráter anticolonial da luta contra o racismo no Brasil
Authors: De Castro Susana
Published: November 2021

O texto pretende analisar o impacto da escravidão colonial no Brasil para as relações sociais nos dias de hoje. O objetivo do texto é refletir porque no Brasil, ao contrário do que ocorreu, por exemplo, na Alemanha após o regime nazista, não ter sido fomentado um sentimento de vergonha, que levasse a culpa e reparação pelo genocídio da população indígena e negra. Minha hipótese é a de que a naturalização e a normalização desses fatos contribuem para a permanência da colonialidade do poder, isto é, de uma distribuição desigual do poder baseada em uma hierarquia entre as raças, e seus efeitos, os racismos estrutural, institucional e cotidiano no Brasil. O/a brasileiro/a tem a ‘branquitude’ como meta e despreza suas origens não europeias. Essa colonização do imaginário conduz a nossa subordinação intelectual e política. Enquanto a população não for capaz de enfrentar o trauma do escravismo, e entender que precisa exigir das autoridades políticas e elites econômicas reparação pelos danos e sofrimentos causados, continuaremos seguindo um ethos colonial, reproduzindo padrões sociais raciais eurocêntricos.
Estética chicha: nuevas formas de creatividad popular en Lima de inicios del siglo XXI
Authors: Quispe Lázaro Arturo
Published: November 2021

En Lima, nuevas formas de creación artística que provienen del ámbito popular se han venido produciendo desde inicios del siglo XXI. Estas creaciones, que proceden del entorno de la música tropical peruana, se conocen como música chicha. Un primer paso significativo fue el cambio de diseño y composición del afiche chicha: pasó de publicitar fiestas de música tropical hacia otro que transmitía ideas. De ese modo, se conectó con otros espacios de lo popular y de la ciudad, deviniendo una diversidad de propuestas creativas a los que se les denominó estética chicha. ¿Por qué en una ciudad como Lima, cosmopolita, altamente interconectada y globalizada emerge y genera impacto una producción artístico-cultural de corte popular y del entorno de la música tropical chicha? ¿Qué características tiene esta estética y qué relación establece con la cultura ancestral en un contexto altamente interconectado?.Estas son algunas de las preguntas que abordaremos en este artículo, focalizado en Lima, durante las dos primeras décadas del presente siglo. La metodología es inductiva: hemos seleccionado un corpus pictórico de las creaciones existentes. Finalmente, planteamos una taxonomía que nos permitió analizar la estética chicha como expresión artística contemporánea.
New Distributional Record of Greater Amberjack Seriola dumerili (Risso, 1810) (Perciformes: Carrangidae) from the Eastern Arabian Sea, India
Authors: Rajesh K.M. , Thomas Sujitha , Sukumaran Sandhya , Purushottama G.B. , Nataraja G.D. , Dineshbabu A.P. , Rohit Prathibha , Zacharia P.U.
Published: November 2021

Background: The fishes of the family Carangidae forms one of the largest families of bony fishes, representing about 140 species, widely distributed in all tropical and temperate marine waters of the world. In recent past, fishes of this family are exhibiting new geographical distribution which could be attributed to climatic variability. Methods: The specimens were collected from multiday trawl boats operated along Karnataka coast. Morphometric and meristic characteristics together with genetic analysis using DNA bar coding was used to validate the identity of the specimen. Spatial distribution map of the species in Indian Ocean was generated using the information from the present study and available literature. Result: The morphometric and meristic characteristics of the specimens of greater amberjack, Seriola dumerili collected during the study were comparable with the previous investigations. The phylogenetic tree constructed using sequences of COI (MW974826 and MW974827) of the Seriola species showed distinct clustering among species with significant bootstrap values confirming the identity to the extent of 99% with the sequences of Seriola dumerili deposited in NCBI GenBank. This study confirms the first distributional record of Seriola dumerili from the eastern Arabian Sea.
​In-vitro Effect of Different Abiotic Stresses on the Growth and Sporulation of Colletotrichum gloeosporioides causing Anthracnose of Mango
Authors: Kannan R. , Dhivya V.
Published: November 2021

Background: Mango productivity was very much affected due to a major fungal pathogen, Colletotrichum gloeosporioides causing anthracnose mango rot. The present study was carried out to investigate the influence of abiotic factors for the support of superficial growth of isolated fungus and finding a minimum inhibitory concentration of different fungicides. Methods: Among four different culture media tested, the highest radial growth and sporulation of the fungus were recorded in Oatmeal agar (OMA) (84 mm) followed by Conn’s agar (CA), Czapek Dox agar (CDA) and Potato dextrose agar (PDA). Among the different pH tested, pH 7.0 was found to be the best in supporting the good radial growth (69 mm) followed by pH 6.0 (56 mm), pH 5.5 (49 mm), pH 7.5 (43 mm) and pH 8.0 (37 mm). Among the various temperature tested, 25oC (69.32) was found to be the best followed by 20oC (52.53 mm), 30oC (65.23 mm) and 35oC. Result: Among the fungicides tested, Zineb 68% + Hexaconazole 4% WP (avtar) was found best as the radial growth was observed to be 45, 41, 36, 32, 25 mm at 5, 10, 25, 50 and 100 ppm, respectively as compared to 80 mm in control. The fungicide Tricyclazole 18% + Mancozeb 62% WP (Merger) was found to be the least effective in checking the radial growth of C. gloeosporioides even at 100 ppm concentration.
Diversity of Colletotrichum Species causing Anthracnose Disease from Mango cv. Nam Dork Mai See Tong based on ISSR-PCR
Authors: Bincader S. , Pongpisutta R. , Rattanakreetakul C.
Published: November 2021

Background: Anthracnose disease caused by the genus Colletotrichum is one of the crucial problems occurring in the field, along with postharvest diseases and affects mango quality in Thailand. In particular, the Nam Dork Mai See Tong cultivar, which is highly susceptible to the disease, is an important product for exportation. Methods: In this research, thirty-seven Colletotrichum species isolate were obtained from anthracnose disease in mango cv. Nam Dork Mai See Tong in three provinces in Thailand. Morphological studies and molecular techniques using species-specific primers were investigated; moreover, the diversity of pathogens was analyzed using PCR amplification of inter simple sequence repeats (ISSRs) with 6 primers, including pathogenicity tests. Result: Morphological studies and molecular detection with species-specific primers revealed that 32 isolates belonged to the C. gloeosporioides species complex and 5 isolates to the C. acutatum species complex. The genetic diversity of pathogens was analyzed. PCR amplification using 6 ISSR primers produced 35 polymorphic bands. These bands were used to construct UPGMA, in which cluster analysis divided the 37 isolates into 3 main groups and 8 subgroups at 61-73% Jaccard similarity coefficient with cophenetic correlation (r) = 0.6781. The ISSR technique showed the greatest genetic variation among isolates collected from different locations. Hence, a study based on ISSR markers was profitable to investigate the phylogenetic relationship of the genus Colletotrichum. Pathogenicity tests revealed that PC006 (Ca) and CS005 (Cg) showed the highest aggressiveness, with disease incidences of 84.74 and 80.90%, respectively. This study indicates that the diversity of pathogenic Colletotrichum species related to mango plantations in Thailand is increasing.
MUHASEBE-FİNANS ALANLARINDAKİ ÖNLİSANS ÖĞRENCİLERİNİN BAŞARILARINDA MÜFREDATIN ETKİSİ: ADIYAMAN ÜNİVERSİTESİ KAHTA MYO ÖRNEĞİ
Authors: İKVAN Abdulrezzak , DEMİRKOL Ömer Faruk
Published: November 2021

Yükseköğretimde akademik başarı düzeyi öğrencinin meslek seçim ve başarısında önemli rol oynamaktadır. Bu bakımdan yükseköğretim kurumlarına akademik başarıda etkin rol oynayan faktörlerin belirlenmesi ve iyileştirilmesinde önemli görevler düşmektedir. Bölüm müfredatlarında yer alan derslerin çeşit ve içerikleri öğrencilerin akademik başarı düzeylerini etkileyen faktörlerdendir. Müfredat derslerinin mesleğin gerekliliklerine uygun ve piyasa koşullarına cevap verebilecek düzeyde güncel olması öğrencilerin ilgi ve motivasyonlarını olumlu etkileyecektir. Çalışmanın amacı muhasebe-finans alanlarında ön lisans düzeyindeki öğrencilerin akademik başarılarında müfredat derslerinin etkisini belirlemektir. Bu amaç doğrultusunda Adıyaman Üniversitesi Kahta Meslek Yüksekokulu Bankacılık ve Sigortacılık Bölümü ile Muhasebe ve Vergi Uygulamaları ön lisans bölümleri 2018-2019 dönemlerinde mezuniyetleri onaylanan toplam 102 öğrencinin transkriptlerinde yer alan ders notlarının akademik başarılarına etki düzeylerini belirlemeye yönelik anova ve t-testi analizleri yapılmıştır. Elde edilen bulgularda Bankacılık ve Sigortacılık Bölümünde öğrencilerin alan derslerinde başarı düzeylerinin yüksek olduğu ve akademik başarında özellikle ikinci ve üçüncü dönemlerin etki düzeyinin diğer dönemlere göre daha fazla olduğu tespit edilmiştir. Muhasebe ve Vergi Uygulamaları Bölümünde öğrencilerin ilk dönemlerde aldıkları meslek derslerinin başarı düzeylerinin genel olarak düşük seviyede olduğu belirlenmiştir. Bu bölümde ise ikinci ve dördüncü dönem notlarının akademik başarı düzeyine etkisinin diğer dönemlere göre daha yüksek düzeyde olduğu belirlenmiştir. Elde edilen sonuçlara göre dönemler itibariyle bölümlerin müfredatlarında yer alacak derslerin öğrencilerin ilgi duydukları ve başarılarının yüksek olduğu derslere yoğunluk verilmesi akademik başarı düzeyinin yükselmesine önemli katkılar sunacağı öngörülmektedir.
Opciones estratégicas de Rusia desde la óptica del neorrealismo ofensivo
Authors: Gonzálvez José
Published: November 2021

Neorealism gives us clues to how States -the main actor in international relations- interact with each other, and being their main mission their own survival, develops specific strategies to ensure it, the reasons for choosing between them, and the actions that they ensure the end goal. It will be within this theoretical framework that an attempt will be made to revisit the special relationship between Russia and China. Once ideological partners, other adversaries as heads of the two largest power structures under the umbrella of socialism, and today, it seems that powers are increasingly close in their common aversion to American power. And yet ... This work tries to identify Russia's strategic options, framed in the paradigm of the realist school.
La traducción de Juarez und Maximilian de Franz Werfel en México
Authors: Morales Zea María del Sol
Published: November 2021

En este artículo se exponen y analizan las dos traducciones al castellano de la obra Juarez und Maximilian, del escritor austriaco Franz Werfel, publicadas en México. El análisis se realiza desde la semiótica cultural, a partir de la teoría de la comunicación expuesta por Göran Sonesson y el proceso de negociación de Umberto Eco. La complejidad de estas traducciones radica en dos aspectos: primero, se trata de una obra que transitó del alemán al inglés y de ahí al español, pero también del alemán al español; y segundo, la necesidad de tener conocimientos de la historia de México para su comprensión. Como resultado, se logra distinguir entre los discursos de cada uno de los textos meta y el texto base, así como su relación con las características biográficas de los traductores y sus competencias culturales, y la utilización de los textos de llegada.
Luis Enrique Osorio (1915-1930): itinerancia juvenil y transferencias culturales
Authors: Agudelo Ochoa Ana María
Published: November 2021

Este artículo revisa la trayectoria de Luis Enrique Osorio entre 1915, año de publicación de su primera obra, y 1930, cuando cierra su ciclo como editor del proyecto La Novela Semanal, con el fin de estudiar sus posturas como autor y editor. La teoría de las transferencias culturales (Espagne;Zapata) y la categoría de postura autorial (Meizoz) permiten comprender las estrategias a las que acudió Osorio para construir una postura de autor y editor, y para tratar de vincularse a la dinámica cultural colombiana de la primera mitad del siglo xx. El análisis permite confirmar que la trashumancia de juventud, su relación con impresos periódicos colombianos y extranjeros, y sus relaciones con escritores, editores e intelectuales latinoamericanos son determinantes en la carrera de Osorio en los circuitos editorial, literario y teatral; no obstante, le resultan insuficientes para consolidar la postura autorial y de editor que anhelaba.
New methods of metaphor identification in various types of discourse (Review of publications)
Authors:   Tyumen State University, Shitikov Peter M. , Vershinina Svetlana V.
Published: November 2021

This article presents a review of the latest procedures for identifying metaphor in multilingual texts and different types of discourse. The choice of methods for identifying and decoding metaphorical expressions is the starting point of any research in the field of metaphorology. With the development of corpus linguistics methods, the volume of analyzed material has grown thousands of times. So, the identification of linguistic expressions in discourse that realize conceptual metaphors has become one of the most challenging issues of modern metaphorology. The paper describes theoretical foundations and historical background for the solution of this issue. It is shown that it is impossible to verify this or that method without a large-scale approbation; in this connection, the developments of research groups (PALASIGMET, PRAGGLEJAZ) proved to be the most perspective. The MIP (metaphor identification procedure) was finalized in the metaphor laboratory of the Free University of Amsterdam with the name MIPVU. This methodology was a great success all over the world, however, in Russia only a few articles of introductory character have appeared. This article summarizes the experience of applying the procedures of metaphor identification in different languages and types of discourse.
Verbal representation of kinemas in the lexicography and space of a literary text (based on the material of Russian and French literature of the XIX–XX centuries)
Authors:   Russian University of Transport, Shirshikov Vladislav B. , Kobzeva Olga V. , Skuybedina Olga N.
Published: November 2021

This article analyses the verbalization of kinemas: the choice of ways and means of their verbal representation in literary texts and dictionaries. Russian -Russian and French-language literature of the 19th and 20th centuries of different genres (dramatic, epic (novels, novellas, short stories, detective stories, plays), as well as Russian-French explanatory dictionaries) were used as the material for the study. The authors used the following contexts: descriptions of verbal representations of kinemas, extracted from modern and classical Russian and French-language literature of the XIX–XX centuries. The analyzed material in lexicography allows us to draw the following conclusions: the frequency of verbalization of the kineme in the Russian language with the reference word "eyes"(250; 45%); in the French language, the most frequent are kinemas with the reference word "hand" (154; 34,2%). The study of modern and classical fiction gives grounds to state that in French texts the frequency of verbalization of kinemas containing a description of gestures is 40%, in Russian texts 30,7%. The most representative are complex RRCS in Russian fiction — 42,4%, and in French texts there is a clear predominance of verbalization of kinemas containing a description of facial expression — 44,2%. It should be noted that the national speech behavior of an individual is determined not only and not so much by his psychological mood and communication conditions, but by his belonging to a certain linguistic and cultural community, which has its own cultural space, cultural interior of the situation, and all this is consistently reflected in the literary text.
The epistolary heritage of Leo Tolstoy at the turn of the XIX–XX centuries: the motive of reading in the estate
Authors:   Kostroma State University, Andreeva Valeria G.
Published: November 2021

Based on the analysis of the letters of Leo Tolstoy 1890–1910 the article analyzes the motive for reading, which is directly related to the estate life. The epistolary heritage of the writer has not yet been fully investigated, and in the study of the estate theme in the work of the late Tolstoy, it plays an important role. Typical for the late XIX — early XX centuries the process of impoverishment of noble estates at this time almost did not touch Yasnaya Polyana. While Tolstoy was alive, his estate remained a kind of energy center. Tolstoy's statements about the works he read in letters make it possible to estimate the volume of his reading, the literature he preferred. The author of the article selected illustrative examples from Tolstoy’s letters with a polar assessment of the works of various writers. The author analyzes the direct messages of the writer about reading as a pastime, hobby, realized mainly in letters to close people: stories about home reading, about the impressions of books. Special attention is paid to reading as the basis for the moral formation of a person and his spiritual growth, as well as the choice of books, the study of which was of decisive importance for the further course of Tolstoy's thought and the direction of his artistic and journalistic work. The article comprehends the role of Tolstoy as a key figure in the literary process at the turn of the century, evaluates its manifestations in the writer’s epistolary heritage.
Technology Updates in Male Infertility Management
Authors: Aucky Hinting  , Agustinus Agustinus
Published: November 2021

Background: Technologies are replacing manpower many fields including medical field. Several devices have been marketed for replacing/reducing manpower in the medical field including male infertility. Here we reviewed several technologies that developed in male infertility.
Review: Computer assisted sperm analysis (CASA), Automatic assessment of biochemical marker of seminal plasma, B-mode ultrasound, and automatic sperm cryopreservation can be applied routinely. Several updates i.e. automatic histopathology assessment, ultrasound strain elastography, magnetic resonance imaging (MRI) stronger than 3.0 T, Artificial intelligence for predicting the presence of sperm in azoospermia cases, automatic sperm selection, and automatic intracytoplasmic sperm injection (ICSI) need more studies before their application.
Summary: Prudent choice based on valid studies is needed in order to give a comprehensive management to patient with male infertility without using useless technology.
The Contribution of Sex Difference on Different Liver Histopathology Between Male and Female Mice After Oral Administration of Caffeine
Authors: Muhammad Sholikhuddin Nafi’  , Tri Hartini Yuliawati  , Prijati Sri Irawati  , Hasanatuludhhiyah Nurina
Published: November 2021

Background: There are several studies reporting the effect of caffeine on liver histopathology, but it remains controversy. The laboratory animal used in those studies were predominantly male, whereas there is contribution of sex difference on different liver reaction to xenobiotic between male and female subject.
Objective: It is necessary to conduct a study to explore the differences between the liver histopathology of male and female mice after oral administration of caffeine.
Methods: This study used 36 mice (Mus musculus) that were divided into 4 groups: male & female untreated groups and male & female treated groups which were orally administered with caffeine 0.4 mg / 20 gramBW daily for 30 days. At the end of treatment, mice were euthanized and dissected. Histopathological examination was done to determine the percentage of  liver cell death of each group.
Results: The percentage of liver cell deathin female treated group was higher than male treated group (p = 0.0001). But there was no significant difference of liver cells death between male control and treated group and between female control and treated group.
Conclusion: There was significant difference in liver histopathology between male and female mice after oral administration of caffeine.
DINAMIKA KOMUNIKASI POLITIK DI KASKUS PADA PERIODE KAMPANYE PEMILIHAN PRESIDEN 5 JUNI - 5 JULI 2014 (Studi pada Aktifitas Kaskuser dalam Pemilihan Presiden 2014)
Authors: Kholil Muhammad Muhtadin
Published: November 2021

General elections is a requisite in democratic system. In the seventh presidential election of Indonesia in 2014, started a lot of use of social networking media such as facebook, twitter, whatsapps, blackberry messenger (bbm), and an internet forum such as Kaskus as an effective communication tool in getting support of society. In a relatively short time, social media can gather a lot of followers. The use of social media by volunteers and supporters not only as a mean of promoting the candidate of president and vice-president, but also conducted black campaign and negative campaign to attack and bring down the rival. Dynamics of social networking community has characteristics of: liquid condition, huge individual freedom, could be used by anyone and for any interest. Kaskus has interactive and very diverse expression as a social networking site. Kaskus loaded with dynamics offorce that can cause changes in the livelihood of the concerned society. The purpose of this study is determining how the dynamics of political communication of one of president candidate, Joko Widodo, on Kaskus forum at the presidential election campaign period (5 June to 5 July 2014). The research method used was qualitative method with content analysis approach. The study concludes that the result of political communication obtained from social media can only generate trust of voters but not as a winning factor.
PROSES TUMBUH DAN BERKEMBANGNYA KOMUNITAS MEREK SEBAGAI GERAKAN SOSIAL
Authors: Chusnaini Azmil
Published: November 2021

Using social movement theory, this study identify factors that influence likelihood and speed of acceptance new brand community. With grounded theory approach, data collected by in-depth interview from 16 informants within 2 famous brand communities. These brand communities exhibit three processes that transform aspiring community from a few costumer who consume similar brand and product become a big brand community that accepted in environment. These processes consist of (1) Differentiation; (2) Legitimacy Building; and (3) Mobilization. The author also reveals some norms call normative community pressure that protect members of community to interact and cooperate within community stay on the right track. Managerial and academic implication also explained how to build and grow brand community which can be very usefull to firms.
TEKNIK MENGUNGKAP TAX FRAUD
Authors: Hermansyah Wawan
Published: November 2021

Fraud is an array of irregularities and illegal act characterized by intention deception. The purpose of this study is to formulate revealed techniques of tax fraud using indirect and direct technique. 1). Indirect technique use vertical analysis, horisontal analysis, and ratio analysis technique, and 2). Direct technique use physics test. The development of this issue can be a solution for tax fraud’s problem in Indonesia. Otherwise, the study is only concerned to find sales transactions without value added tax and sales transactions that only paid a part to treasury find.This study is qualitative research with the Source of research data are balance, income statement, and cash flows statement. The method of collecting data use participation of observation. And then analysis of research data use hermeneutics.These result indicate that vertical test analysis technique and horizontal analysis technique have significant percentage and ratio analysis techniques showed indications of fraud with score M > 5,24. Besides, based on the result of physical tests showed that PT. NN less deposit the tax obligatios and hasn’t paid value added tax to treasury fund.
PENGARUH MOTIVASI DAN STRES KERJA TERHADAP KINERJA DENGAN KETERLIBATAN KERJA SEBAGAI VARIABEL INTERVENING ( STUDI PADA KARYAWAN BAGIAN PRODUKSI ) PT. FITRAFOOD INTERNATIONAL
Authors: Darwin Darrylia Jennyfer
Published: November 2021

Tujuan dari penelitian ini adalah untuk mengetahui adanya pengaruh motivasi dan stress kerja terhadap kinerja dengan keterlibatan kerja sebagai variable intervening (studi pada karyawan bagian produksi) PT. Fitra Food International yang berjumlah 102 orang. Metode pengumpulan data yang digunakan dalam penelitian ini membaca literature- literature dan penelitian sebelumnya dan penyebaran kuesioner. Data yang dianalisis dari hasil tersebut diolah dengan path analisis. Pengujian validitas dilakukan dengan bantuan SPSS 16.0 for windows dan model pengukuran yang diperoleh dari pengolahan data menggunakan AMOS yang menunjukkan hasil penelitian menunjukkan bahwa variable motivasi kerja berpengaruh signifikan terhadap keterlibatan kerja, kemudian variable stress kerja berpengaruh signifikan terhadap keterlibatan kerja, lalu variable keterlibatan kerja berpengaruh signifikan terhadap kinerja karyawan, kemudian variable motivasi kerja berpengaruh signifikan terhadap kinerja karyawan dan variable stress kerja berpengaruh signifikan kinerja karyawan. Kata kunci: motivasi, stress kerja, kinerja, keterlibatan kerja
PENGARUH STRUKTUR KEPEMILIKAN MANAJERIAL, STRUKTUR KEPEMILIKAN INSTITUSIONAL, SET KESEMPATAN INVESTASI, UKURAN PERUSAHAAN TERHADAP NILAI PERUSAHAAN
Authors: Nugroho Purwo Adi
Published: November 2021

The main purpose of this study was to determine the effect of managerial ownership structure, institutional ownership structure, investment opportunity set and firm size on firm value. The population of this study is a real estate company that listed on the Indonesia Stock Exchange with the observation period 2008 to 2012. Data obtained by the method of purposive sampling and the 42 companies sampled each year. The method of analysis used is multiple linear regression by using SPSS 20.0. The results of this study indicate that: (1) managerial ownership structure has no effect on firm value, (2) institutional ownership structure has significant effect on firm value, (3) investment opportunity set has significant effect on firm value, and (4) firm size has significant effect on firm value.
The role of Applied Higher Education in achieving the SDGs: The Example from the Faculty of Vocational Studies at Universitas Airlangga
Authors: Kristanto Damar , Soleh Mochammad , Suharno Novianto Edi , Aji Gagas Gayuh
Published: November 2021

Abstractthe whole world has been made aware of the importance of sustaining human life on this earth. The economic improvement felt in the last decade is the result of increasing industrialization around the world. This has a fairly serious impact in terms of natural damage and social life. Fundamental changes are urgently needed to break the chain of socio-environmental damage that threatens the survival of future generations. These fundamental changes can be started from changes in the concept of education. Education is still considered the key to development both in terms of human resources and innovation. Applied education can be a door in the teaching of new abilities and skills based on the SDGs. This study aims to describe the role of applied or vocational education in achieving SGDs. The Faculty of Vocational Studies at Universitas Airlangga can be an example of how applied higher education institutions have the potential to achieve the SDGs goals. Based on the results of our study, it appears that the role of applied educational institutions has the potential to achieve the SDGs targets. The results of this study have a significant impact on future policy directions and institutional development. Keywords: SDGs, higher education institution, sustainable development, thematic analysis.
Sobre a certeza sensível e o problema do começo da filosofia
Authors: Lima Filho José Edmar , Dacuy Maximiliano
Published: November 2021

O presente artigo pretende analisar os conceitos de certeza sensível em Hegel e Feuerbach, partindo da exposição do primeiro capítulo da Fenomenologia do Espírito (Phänomenologie des Geistes [1807]) hegeliana e do texto feuerbachiano Para a crítica da filosofia de Hegel (Zur Kritik der Hegelschen Philosophie [1839]). Em um primeiro momento a exposição é orientada pela perspectiva hegeliana, a qual defende a tese de que, enquanto a consciência sensitiva tem a pretensão de alcançar a verdade do objeto como algo singular e isento de mediações e que, por isso, acredita ter a posse do saber mais verdadeiro e rico, passa por contradições que não pode resolver sem dar o salto para o nível da percepção; o que parecia singular lhe parece agora universal, e o “saber” pretensamente rico, se revelará o mais pobre e vazio abstrato. No segundo momento, lendo a supracitada obra de Feuerbach, temos que a certeza sensível, tal como considerada pela Fenomenologia, não passa de um jogo de palavras do pensamento consigo mesmo; a tese agora é a de que Hegel parte de um conceito de sensibilidade distinto da realidade efetiva e que, portanto, a refutação hegeliana só se dá logicamente, mas não realmente em relação à verdade da certeza sensível.
MIDIATIZAÇÃO: AÇÃO OU EFEITO DE MIDIATIZAR
Authors: De Mendonça Melo Angelina
Published: November 2021

Por meio da introdução teórica sobre o tema, percebe-se que o ato ou efeito de midiatizar, encontra-se na contextualização da cultura pós-moderna, de lógicas e operações de natureza midiática e que se inscrevem na vida da sociedade, permeando e constituindo suas formas de organização e funcionamento, definindo condições de acesso e consumo por parte dos indivíduos, sendo a partir deste consumo, os variados segmentos para determinados públicos.   Com tantas especificações sobre mídia, estudar esse fenômeno é algo atraente e desafiador, pois envolve toda uma sistemática de ideias, ainda em processo de desenvolvimento infinito, já bem conceituada, por autores que abordam e abordaram o tema no decorrer de décadas por todo o mundo, alguns deles trazidos aqui neste artigo.  Portanto, os estudos sobre a Midiatizaçãoé importante, por despertar aguçados sentimentos de descobertas e por sua tamanha utilidade social e pública na contemporaneidade, também pelo poder de persuasão, por intermédio da força discursiva e pela capacidade de construir variados entendimentos sobre a realidade no cotidiano.
YENİLİK ALGISININ, ALGILANAN ÖRGÜTSEL DESTEĞE ETKİSİNDE KOLEKTİF ŞÜKRANIN ARACI ROLÜ: KARS İLİ ÖĞRETMENLERİ ÜZERİNE BİR İNCELEME
Authors: ÇAYALAN Hakan , ÇAYALAN Nilgün
Published: November 2021

Bu çalışmada yenilik algısının, algılanan örgütsel desteğe etkisinde kolektif şükranın moderator etkisi incelenmiştir. Bu kapsamda yenilik algısı, algılanan örgütsel destek ve kolektif şükranın aracı rolü sosyal mübadele teorisi kapsamında irdelenmiş ve literatüre katkıda bulunmak amaçlanmıştır. Araştırma evrenini Kars ilindeki puanla öğrenci alan beş proje lisesinde görev yapan 154 öğretmen oluşturmaktadır. Veri toplama araçlarından anket tekniği kullanılmıştır. Anket tekniği ile toplanan veriler SPSS programı ile analiz edilmiştir. Çalışma kurgusunda Milli Eğitim Bakanlığı’nın FATİH projesine ilişkin Kars ili proje liselerinde görev yapan öğretmenlerin yenilik algısının örgütsel destek algısını etkileyeceği ve kolektif şükranın bu etkiye aracılık edeceği öngörülmüştür. Araştırma bulguları yenilik algısının algılanan örgütsel destek üzerinde istatistiki düzlemde anlamlı pozitif bir etkiye sahip olduğunu ortaya koymaktadır. Ayrıca bu etki üzerinde kolektif şükranın kısmi etkiye sahip olduğu tespit edilmiştir. Araştırma sonucunda kamu ve özel sektör kurum ve kuruluşlarına, idareci, yönetici ve uygulayıcılara önerilerde bulunulmuştur.
South Africa’s 2016 municipal elections How the ANC and DA leveraged Twitter to Capture the Urban Vote
Authors: Adebayo Joseph Olusegun , Makwambeni Blessing , Thakur Colin
Published: November 2021

This paper focuses on how South Africa’s governing party, the African National Congress (ANC), and main opposition, the Democratic Alliance (DA), leveraged microblogging site Twitter. This was part of their urban election campaign arsenal in the 2016 local government elections (LGE) to promote party-political digital issue ownership within an urban context. Using each party’s corpus of 2016 election-related tweets and election manifestos, this three-phased grounded theory study found that each party used Twitter as a digital political communication platform to communicate their election campaigns. The DA notably leveraged the social networking site more for intense focused messaging of its negative campaign against the ANC while simultaneously promoting positive electoral messages around its own core issues and metro (urban) mayoral candidates. Furthermore, battleground metros were identified, narrow-cast and subsequently audience.segmented by the party in Ekurhuleni, Johannesburg, Tshwane (in Gauteng) and Nelson Mandela Bay (in the Eastern Cape). This led to an emphasised campaign to either activate the party’s own urban support base and/or to suppress the ANC’s turnout in these highly-contested areas. The results of this study further indicate that the ANC and DA both used Twitter to claim explicit and implicit digital party-political issue ownership in the 2016 LGE.
Zimbabwe’s 2018 harmonised elections An Assessment of Credibility
Authors: Rusinga Rekai
Published: November 2021

This paper assesses the credibility of Zimbabwe’s 2018 harmonised elections using an electoral cycle approach, arguing that the free expression of voters’ choice is a sine qua non for credibility. A study of Election Observer Missions’ reports (EOMs), media reports, and observation in relation to the 2018 elections, points to inadequate legal reforms; questionable independence and impartiality of the Elections Management Body (EMB); media bias; partisan distribution of aid; abuse of state resources; vote buying; partisan involvement of traditional leaders and of the military; intimidation; and suspicious results management. The paper concludes that the 2018 harmonised elections did not pass the credibility test owing to the cumulative effect of structural inadequacies. There is thus a need to comprehensively reform Zimbabwe’s electoral laws, improve elections administration, and ensure a level playing field for contestants by addressing the political environment within which elections are held.
Imagining Sustainable Human Ecosystems with Power-to-x in-situ Resource Utilisation Technology
Authors: Baldry Mark , Gurieff Nicholas , Keogh Declan
Published: November 2021

Extensive in-situ resource utilisation (ISRU) will be essential to enable long-duration stays on Luna and Mars and reduce reliance on resupply from Earth. Early development of ISRU technologies has focused on standalone capabilities for specific targets related to life support and ascent propellant. An unexplored opportunity remains for greatly expanding the scope of materials that can be supplied by ISRU, and for integrating various technology platforms into a larger system. Recent advances in power-to-X technology aimed at decarbonising the global economy have made it possible to drive key chemical processes using electricity with small-scale, modular reactor. This paper proposes a vision for an integrated system of ISRU processes based on power-to-X technology to produce oxygen, hydrogen, water, methane, polymers, metal alloys, and synthetic fertilisers, using Martian regolith, atmosphere, and ice. A ‘building block’ strategy is adopted to convert raw materials into versatile intermediaries, which can then be combined to form essential products. A wider range of raw materials are available on Mars compared to Luna, suggesting greater opportunity for ISRU deployment to compensate for the greater time and cost requirements for a Mars resupply mission.
Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series
Authors: De Rose Cristina , Miceli Sopo Stefano , Valentini Piero , Morello Rosa , Biasucci Daniele , Buonsenso Danilo
Published: November 2021

In recent years, lung ultrasound (LUS) has been increasingly used for the diagnosis of respiratory diseases in both adult and pediatric patients. However, asthma is a field in which the use of LUS is not yet well defined or is in development. In the following case series, we describe clinical, laboratory, radiological results as well as detailed lung ultrasound findings of 6 children with asthma: some of them with acute asthma attack and with inadequately controlled allergic asthma or childhood asthma; others with acute asthma and allergic or infantile asthma adequately controlled by preventive therapy. Finally we describe the clinical, laboratory and imaging parameters of a child with severe allergic asthma in the absence of exacerbation. In these cases, albeit at different times, LUS played an important role in both the initial diagnostic process and follow-up. It also showed different ultrasound features depending on the severity of the individual asthma based on the type of asthmatic phenotype and control of it.
Enhancing Handover for 5G Mobile Networks using Jump Markov Linear System and Deep Reinforcement Learning
Authors: Chiputa Masoto , Zhang Minglong , Ali G. G. Md. Nawaz , Chong Peter Han Joo , Sabit Hakilo , Kumar Arun , Li Hui
Published: November 2021

The fifth Generation (5G) mobile networks use millimeter Waves (mmWaves) to offer giga bit data rates. However, unlike microwaves, mmWave links are prone to user and topographic dynamics. They easily get blocked and end up forming irregular cell patterns for 5G. This in turn cause too early, too late, or wrong handoffs (HOs). To mitigate HO challenges, sustain connectivity and avert unnecessary HO, we propose a HO scheme based on Jump Markov Linear System (JMLS) and Deep Reinforcement Learning (DRL). JMLS is widely known to account for abrupt changes in system dynamics. DRL likewise emerges as an artificial intelligence technique for learning highly dimensional and time-varying behaviors. We combine the two techniques to account for time-varying, abrupt, and irregular changes in mmWave link behaviour by predicting likely deterioration patterns of target links. The prediction is optimized by meta training techniques that also reduces training sample size. Thus, the JMLS-DRL platform formulates intelligent and versatile HO policies for 5G. Results show our proposed prediction scheme about target link behavior post HO to be highly reliable. The scheme also averts unnecessary HOs thus ably supports longer dew time.
Worming the Circular Economy for Biowaste and Plastics: Hermetia illucens, Tenebrio Molitor and Zophobas morio
Authors: Kuan Zhi-Jue , Chan Barnabas Kuan-Nang , Gan Samuel Ken-En
Published: November 2021

The negative impact of the modern-day lifestyle on the environment is aggravated during the COVID-19 pandemic through the increased use of single-use plastics from food takeaways to medical supplies. Similarly, the closure of food outlets and disrupted supply chains have also resulted in significant food wastage. As the pandemic rages on, the aggravation of increased waste becomes an increasingly urgent problem that threatens the biodiversity, ecosystems, and human health worldwide through pollution. While there are existing methods to deal with the organic and plastic waste, many of the solutions also cause additional problems. Increasingly proposed as a natural solution to man-made unnatural problems, there are insect solutions for dealing with the artificial and organic waste products towards a circular economy, making the use of natural insect solutions commercially sustainable. This review discusses the findings and how some of these insects, particularly the Hermetia illucens, Tenebrio molitor, and Zophobas morio, can play an increasing important role in food and plastics, with a focus on the latter.