bluuebunny/crossref_metadata_2025 huggingface dataset:
Early mobilization and length of wound healing post-sectio caesarean: A cross-sectional study
Authors: Yulianti Lisa , Yunita Laurensia , Mariana Frani , Palimbo Adriana
Published: February 2025

Background: Mobilization post sectio caesarean is an effort to prevent risk and complications of infection. The early mobilization stages are the first hour after surgery, lie down first, move the arms, bend and slide the legs, and lift the heels, six to ten hours after surgery woman is required to turn her body to the right and left side.
Objective: To determine the correlation between early mobilization with length of wound healing post-sectio caesarean.
Method: A quantitative analytical study with a cross-sectional approach. The study included 30 women who had had a caesarean from September to November 2023. The research instruments used were a questionnaire and an early mobilization observation sheet. Wound healing was measured by means of the REEDA scale. Chi-square test for statistical analysis.
Results: The results showed that there were 22 respondents in good category 73.3%, and 27 people in fast wound healing category 90%. The chi-square test obtained a p-value of 0.014, it was mean that there was a significant relationship between early mobilization and length of wound healing post-sectio caesarean.
Conclusion: The application of early mobilization is effective in overcoming physical mobility disorders so that women post-sectio caesarean can return to their activities.
Analysis of factors related to the high choice of injectable contraceptives by acceptors
Authors: Setyabudhi Mandhareta , Kabuhung Elvine Ivana , Nuwindry Iwan , Iswandari Novita Dewi
Published: February 2025

Background: Three-monthly injectable contraception is a contraceptive method that works by releasing the hormone progesterone into the bloodstream. The impact of using injectable contraception is that menstrual disorders are often found, and fertility is delayed by four to five months. In 2023, 37.3% of acceptors chose three-monthly contraceptive injections, 18.4% pills, 15.2% implants, 14.2% monthly injections, 8.6% intrauterine device, 6.1% condoms, and tubectomy of 0.4%.
Objective: Analysis of factors related to the high choice of injection contraceptives by acceptors.
Method: Quantitative analytical survey research with a cross-sectional approach was conducted to assess age groups, education levels, parity, level of knowledge, and attitudes in choosing injectable contraception. Data were collected using a questionnaire and analyzed using the Chi-square and Fisher's exact tests.
Results: The largest number of contraceptive acceptors were 20 people of early childbearing age, 26 people with elementary and middle school education, 27 people with multipara, 22 people with good knowledge, and 30 people with a positive attitude. The choice of contraceptive device is related to age (p=0.021), education level (p=0.021), parity (p=0.017), level of knowledge (p=0.009), and attitude (p=0.024) of the acceptor.
Conclusion: Age, education level, parity, level of knowledge, and attitudes are factors that influence the choice of injectable contraceptive acceptors.
The incidence of incomplete abortion and the prevalence of abortion-related morbidity in South African public hospitals, 2018
Authors: Conco D N , Levin J , Komane B , Blanchard K , Bessenaar T , Nkosi N G , Fonn S
Published: February 2025

Background. The occurrence of abortion-related morbidity indicates limited access to safe abortion. Globally, unsafe abortions remain a persistent, yet preventable, cause of maternal mortality. South Africa (SA) is internationally recognised for its progressive reproductive rights framework, supported by its Constitution and laws. However, evidence suggests that women encounter barriers to accessing safe abortions, including stigma, resistance from healthcare providers, a shortage of trained professionals and a lack of awareness of their rights. We hypothesised that, 20 years after the promulgation of the Choice on Termination of Pregnancy Act, the incidence of incomplete abortion (ICA) and the prevalence of abortion-related morbidity would change, influenced by access to safe abortion and the introduction of medication abortion. We wanted to compare our data with 2000 and 1994 survey results to assess change.
Objectives. To estimate the incidence of incomplete abortion and describe the prevalence of abortion-related morbidity in SA public hospitals in 2018.
Methods. This was a cross-sectional, retrospective study. We selected a stratified random sample of public hospitals. We extracted data from medical records of women who presented with ICA during a predetermined 21-day period in 2018. Data were captured directly into a REDCap database. To estimate the national incidence of ICA, we used population estimates for 2018, comprising 17 199 227 women aged 12 - 49 years, and 1 200 436 live births. The prevalence of ICA morbidity is reported. We compared the rates in this study with those reported from similar studies in 2000 and 1994.
Results. We found 913 medical records of women presenting with ICA in the 56 public hospitals. ICA incidence was 367 (274 - 459) per 100 000 women aged 12 - 49 years. The average age of the women was 27 years, and the majority had a previous pregnancy before the ICA. A large proportion (73.9%) of women were in the first trimester. There was no sign of infection in 92.5% of records, no organ failure in 99.1% of records and there were no deaths. There was no change in the ICA incidence when compared with the 1994 and 2000 results. Women’s mean age and having a previous pregnancy were similar in the three studies (1994, 2000 and 2018). The proportion of women presenting in the first trimester increased over time: 60.5% in 1994, 67.1% in 2000 and 73.9% in 2018. There has been a decline in the prevalence of abortion-related morbidity, demonstrated by lower levels of severity, no signs of infections and no organ failure.
Conclusion. ICA incidence has not changed, but related morbidity is declining. Various factors could explain our findings, but the lack of change in ICA incidence indicates that access to formal abortion care has not improved over the past 20 years.
Sustainable development goals and corporate sustainability reporting: a bibliometric analysis
Authors: Gallego-Nicholls José Fernando , Ortigosa-Blanch Arturo , Sánchez-García Javier , Rivera-Lirio Juana María
Published: February 2025

Objective: This study analyses corporate sustainability reporting on the Sustainable Development Goals (SDGs) since 2016, identifying trends, gaps, and areas for development in corporate practices and academic research. It addresses five research questions concerning the development of research, productive authors, emerging subtopics, relevant regions and institutions, and conceptual gaps in this field.
Methodology: A bibliometric analysis of 589 publications from 2017 to 2022 was conducted using the Web of Science Core Collection to map the research community and citation trends.
Results: The analysis revealed a highly interconnected research community with significant citation growth, indicating expanding interest, especially in regions like Wales, Denmark, and Switzerland. Interdisciplinary engagement is increasing with contributions from environmental sciences and health research.
Limitations: The study is limited to publications within the Clarivate database and may not capture all global research activities. Rapid changes in corporate reporting may outpace academic documentation.
Practical implications: Corporations need more integrated and empirically supported sustainability indicators. Exploring blockchain technology to enhance reporting reliability offers a novel approach. The study serves as a reference for practitioners aligning corporate strategies with SDG targets and for policymakers strengthening reporting frameworks.
La télé-réalité au prisme de la littérature romanesque : un imaginaire dystopique pour penser les mutations du monde contemporain
Authors: Barrette Pierre , Boisvert Stéfany
Published: February 2025

Cet article explore la représentation de la télé-réalité dans la littérature romanesque contemporaine. À travers l’étude de quatorze romans publiés depuis les années 2000, il est montré que plusieurs thématiques s’y recoupent et nous permettent, si ce n’est de mieux comprendre la télé-réalité elle-même, du moins de mettre en lumière ce que pourrait être un imaginaire littéraire de la télé-réalité. Il est ainsi montré comment ces oeuvres décrivent la télé-réalité pour en critiquer les dérives et la représenter comme un phénomène dystopique, incarnant l’aliénation et la manipulation des masses. En plus d’établir plusieurs parallèles entre la télé-réalité et des tragédies historiques, la plupart des romans mettent en lumière ses effets potentiellement destructeurs sur la société, exacerbant ses tendances au voyeurisme, à l’exhibitionnisme, à l’exploitation et au narcissisme. Tout en mettant l’accent sur les dérives morales d’une société fascinée par la télé-réalité, les oeuvres tendent toutefois à reconduire une vision critique de la télé-réalité en tant que danger de « féminisation » de la culture. L’article souligne ainsi l’importance de ce genre télévisuel dans la compréhension des mutations médiatiques et sociales de notre époque.
Formulation and evaluation of famotidine-loaded nanosponges for the treatment of peptic ulcer: In vitro and in vivo evaluation
Authors: Kumari Priya , Upadhyay Navneet Kumar , Varma Rahul , Kumar Shivam , Gharti Laxmi , Kaurav Hemlata
Published: February 2025

Famotidine (FAM) is a potent blocker of histamine H2 receptors that is widely used to prevent and treat peptic ulcers. Very low oral bioavailability (40%–50%) has been reported due to its gastric degradation and poor solubility, which limits its clinical applicability. FAM-loaded nanosponges (NSs) were formulated using the emulsion solvent evaporation method to increase their therapeutic efficacy and characterized for percentage yield, entrapment, particle size distribution, and in vitro drug release. The optimized formulation showed a particle size of 204.88 nm with entrapment efficiency of 66.59% and sustained drug release of 76.75% ± 0.68% for up to 12 hours. In vivo pharmacokinetic study showed that mean Cmax and AUC0–12 in the group administered with NS3 was 1.78 and 1.70 folds higher than the group administered with pure drug, which showed improved oral bioavailability of FAM when loaded into NSs. Moreover, in animals administered with optimized FAM-loaded NSs, the ulcer index was found to be 5.77% ± 0.69% in comparison to 19.23% ± 0.82% in the group administered with FAM solution and 28.72% ± 0.97% in the ulcer control group. Results of the study suggested that NSs are a promising tool for enhancing the oral bioavailability of FAM in the treatment of peptic ulcers.
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity
Authors: Giménez-Orenga Karen , Martín-Martínez Eva , Nathanson Lubov , Oltra Elisa
Published: February 2025

Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent co-appearance and etiology. Despite prior detection of human endogenous retrovirus (HERV) activation in these diseases, the potential biomarker value of HERV expression profiles for their diagnosis, and the relationship of HERV expression profiles with patient immune systems and symptoms had remained unexplored. By using HERV-V3 high-density microarrays (including over 350k HERV elements and more than 1500 immune-related genes) to interrogate the transcriptomes of peripheral blood mononuclear cells from female patients diagnosed with ME/CFS, FM or both, and matched healthy controls (n=43), this study fills this gap of knowledge. Hierarchical clustering of HERV expression profiles strikingly allowed perfect participant assignment into four distinct groups: ME/CFS, FM, co-diagnosed, or healthy, pointing at a potent biomarker value of HERV expression profiles to differentiate between these hard-to-diagnose chronic syndromes. Differentially expressed HERV-immune-gene modules revealed unique profiles for each of the four study groups and highlighting decreased γδ T cells, and increased plasma and resting CD4 memory T cells, correlating with patient symptom severity in ME/CFS. Moreover, activation of HERV sequences coincided with enrichment of binding sequences targeted by transcription factors which recruit SETDB1 and TRIM28, two known epigenetic silencers of HERV, in ME/CFS, offering a mechanistic explanation for the findings. Unexpectedly, HERV expression profiles appeared minimally affected in co-diagnosed patients denoting a new nosological entity with low epigenetic impact, a seemingly relevant aspect for the diagnosis and treatment of this prevalent group of patients.
On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting
Authors: Zanetti Flavia A , Fernández Ignacio , Baquero Eduard , Guardado-Calvo Pablo , Ferrino-Iriarte Andres , Dubois Sarah , Morel Etienne , Alfonso Victoria , Aguilera Milton O , Celayes María E , Polo Luis M , Suhaiman Laila , Galassi Vanesa V , Chiarpotti María V , Allende Carolina , Rodríguez Javier M , Castón José R , Lijavetzky Diego , Taboga Oscar , Colombo María I , Del Pópolo Mario G , Rey Félix A , Delgui Laura R
Published: February 2025

Birnaviruses are a group of double-stranded RNA (dsRNA) viruses infecting birds, fish and insects. Early endosomes (EE) constitute the platform for viral replication. Here, we study the mechanism of birnaviral targeting of EE membranes. Using the Infectious Bursal Disease Virus (IBDV) as a model, we validate that the viral protein 3 (VP3) binds to phosphatidylinositol-3-phosphate (PI3P) present in EE membranes. We identify the domain of VP3 involved in PI3P-binding, named P2 and localized in the core of VP3, and establish the critical role of the arginine at position 200 (R
200
), conserved among all known birnaviruses. Mutating R
200
abolishes viral replication. Moreover, we propose a two-stage modular mechanism for VP3 association with EE. Firstly, the carboxy-terminal region of VP3 adsorbs on the membrane, and then the VP3 core reinforces the membrane engagement by specifically binding PI3P through its P2 domain, additionally promoting PI3P accumulation.
Microbiota from young mice counteracts susceptibility to age-related gout through modulating butyric acid levels in aged mice
Authors: Song Ning , Gao Hang , Li Jianhao , Liu Yi , Wang Mingze , Ma Zhiming , Zhang Naisheng , Zhang Wenlong
Published: February 2025

Gout is a prevalent form of inflammatory arthritis that occurs due to high levels of uric acid in the blood leading to the formation of urate crystals in and around the joints, particularly affecting the elderly. Recent research has provided evidence of distinct differences in the gut microbiota of patients with gout and hyperuricemia compared to healthy individuals. However, the link between gut microbiota and age-related gout remained underexplored. Our study found that gut microbiota plays a crucial role in determining susceptibility to age-related gout. Specifically, we observed that age-related gut microbiota regulated the activation of the NLRP3 inflammasome pathway and modulated uric acid metabolism. More scrutiny highlighted the positive impact of ‘younger’ microbiota on the gut microbiota structure of old or aged mice, enhancing butanoate metabolism and butyric acid content. Experimentation with butyrate supplementation indicated that butyric acid exerts a dual effect, inhibiting inflammation in acute gout and reducing serum uric acid levels. These insights emphasize the potential of gut microbiome rejuvenation in mitigating senile gout, unraveling the intricate dynamics between microbiota, aging, and gout. It potentially serves as a therapeutic target for senile gout-related conditions.
Immigrant parents’ experiences and perspectives on the early childhood education stages in Nordic contexts
Authors: Migdad Samah M. , Lea Kjersti , Sjøen Martin M.
Published: February 2025

To explore the state of research on immigrant parents’ experiences in early childhood education (ECE) stages, we conducted a literature review through a qualitative meta-synthesis of 22 studies. Guided by sociocultural theory, which emphasizes the co-construction of meaning and the interplay between individual agency and social context, the synthesis highlights both the barriers immigrant parents face and opportunities for enhancing inclusion and support within Nordic ECE contexts. While the articles acknowledge these challenges, they also found that some parents increasingly appreciate Nordic ECE values and practices over time. Communication emerges as a central theme in the reviewed literature; it deeply impacts the integration process of immigrant parents in Nordic ECE systems. Synthesized findings across the studies highlight communication as a key factor shaping parents’ experiences within the categories of “initial experiences and adaptation,” “parental concerns,” and “cultural and social integration.” The review reveals a predominance of host-country researchers, the majority being female, with minority groups underrepresented, which could potentially lead to biases. Despite methodological limitations that impact the understanding of immigrant parents' experiences, the studies offer valuable insights into the parents’ reported experiences and provide a foundation for improving inclusivity and understanding in Nordic ECE.
Enriched Vermicompost Made through Bio Waste of Soybean Stover (Dry Matter) and Fresh Cow Dung Using Earthworms (Eisenia fetida spp.)
Authors: Patel Kamal Kishor , Baghel S. S. , Agrawal S. B. , Rai H. K. , Sahu R. K. , Singh Umesh , Shah Ajay Kumar , Priya
Published: February 2025

This investigation was associated with different materials and techniques on bio-fertilizer application in soybean stover (dry matter) and fresh Cow dung for effect of bio fertilizer and earthworms (Eisenia fetida sp.) on bio waste decomposition. This study was analyzed by RBD (Randomized Block Design) with 6 treatments have to bio fertilizers combination i.e. (E1-control, E2- Rhizobium, E3- Rhizobium+ PSB, E4-Rhizobium+ KSB, E5-Rhizobium+ PSB+KSB, and E6-Rhizobium+ PSB+ KSB+ Trichoderma) and earthworms with 4 replications. The research was conducted at MRPC in Department of Soil Science and Agricultural Chemistry, JNKVV, Jabalpur during the Rabi season of 2021-22 and 2022-23. The result interpreted by partial decomposition, duration of completion, conversion rate and recovery percentage of vermicomposting. The result revealed that partial decomposition (kg) found in enriched vermicompost higher to lower sequence i.e. E5 (7.11 kg)> E3 (7.18 kg) > E2 (7.19 kg) > E4 (7.20 kg) = E6 (7.20 kg) > E1 (7.28 kg) from initial weight (10 kg). The production of enriched vermicompost maximum found in E6 (5.58, 5.63 and 5.61 kg pot-1) within respective duration (42, 40 and 41 days) of vermicomposting in sequent years and statically pooled analysis. Conversion rate and recovery percentage of enriched vermicompost were increase with the combination of bio-agents. This investigation useful to making vermicompost using of agricultural waste through bio-fertilizer.
Evaluation of Farming System Modules for Improving Profitability of Small Farmers in Coastal Odisha, India
Authors: Das Sayani , Behera Bibhuti Bhusan , Das Nishith , Mohanta Ramya Ranjan , Patra Alok Kumar
Published: February 2025

The study evaluated the profitability, sustainability and environmental impact of integrated farming system (IFS) modules, including cropping systems, horticulture, dairy, poultry and fishery in an area of 1.2 ha, in coastal Odisha, India. This research project was part of the sixth production cycle under the All India Coordinated Research Project on IFS and conducted at the Central Research Station, Odisha University of Agriculture and Technology, Bhubaneswar, during the 2022-23 agricultural year. The experiment integrated five major modules: cropping systems (0.32 ha), horticulture (0.31 ha), dairy (2 cross-bred cows), poultry (500 coloured chicken for meat) and fishery (0.40 ha). Productivity was assessed using rice equivalent yield (REY) and economic returns were calculated for each module. Sustainability was evaluated through sustainable yield indices and carbon footprint assessments, while soil quality parameters, such as bulk density, pH, organic carbon and available macronutrients, were monitored over six years. Dairy emerged as the most productive module, yielding the highest REY (15.14 t) and gross return (Rs.3,27,040). Horticulture recorded the highest net return (Rs.1,40,627) and benefit-cost ratio (3.61). The cost of production was mainly influenced by external inputs (52%), followed by labour (33%) and system-recycled inputs (15%). The system generated 399 man-days annually, with over half contributed by dairy. Environmental sustainability was achieved through agroforestry and compost application, making the model carbon-negative. Dairy was the largest greenhouse gas emitter, while horticulture and biomass contributed significantly to carbon sequestration. Over six years, soil quality improved, with reduced bulk density, increased water-holding capacity and enhanced organic carbon levels. Sustainable yield indices for four modules were above 0.6, with dairy showing the highest sustainability. Poultry performance required further improvement to enhance overall system sustainability. In conclusion, the integrated farming system enhanced overall productivity, profitability and environmental sustainability for smallholder farmers in coastal Odisha, showcasing its potential for resource optimization and resilience.
Screening of Black Gram Genotypes for Resistance to Whitefly, Bemisia tabaci (Gennadius) in Southern Telangana, India
Authors: Satwika Maharaj , Kavitha Kosnam , Sridevi Gajula , Aparna Kuna , Basha Shaik Ameer , Devi K. Rukmini
Published: February 2025

Black gram (Vigna mungo L. Hepper) ranks as the third most important pulse crop in India, but it is highly vulnerable to various insect pests throughout its growth. Among these, the whitefly is a prominent sucking pest. A study conducted during Rabi 2023 at the Student Farm, College of Agriculture, Rajendranagar, Hyderabad, aimed to identify black gram genotypes resistant to whitefly. Twenty-eight genotypes were evaluated under field conditions using a whitefly leaf injury grade scale and a whitefly resistance index. The screening identified three resistant genotypes, six moderately resistant, fourteen moderately susceptible and five susceptible genotypes. The genotypes PU-31, TBG-104 and GBG-1 with the lowest whitefly populations per plant (2.81, 3.40, and 3.99, respectively), were classified as resistant. Whereas, the genotypes MBG-1240, MBG-1226, MBG-1221, MBG-1155 and MBG-207 with the highest whitefly populations per plant (7.71, 7.75, 7.79, 8.11 and 8.05, respectively) were categorized as susceptible.
Preventive Effects of Ocimum gratissimum (Lamiaceae) Leaf Decoction on Pilocarpine-induced Seizure and Anxiety in White Mice (Mus musculus Swiss)
Authors: Adrien Lamare Tchachoua , Kidjama Ngo Ngimout , Stéphanie Njapdounke Kameni Jacqueline , Madi Hassan , Flore Ngassa Kimen Léocadie , Emmanuel Wangbara Alkali , Jacques Midala Kodji Jean , Germain Taiwe Sotoing , Elisabeth Ngo Bum
Published: February 2025

The objective of this work was to evaluate the effects of leaf decoction of Ocimum gratissimum (24.4, 61, 122 and 244 mg/kg) on seizures and anxiety during pilocarpine-induced epileptogenesis in mice Mus musculus Swiss. To evaluate anticonvulsivant and anxiolytic effect of Ocimum gratissimum, a pathological model of pilocarpine-induced temporal epilepsy, behavioral tests and analyses of biochemical parameters (malondialdehyde, reduced glutathione, GABA and GABA-transaminase) were used to verify its properties on pilocarpine-induced seizures, oxidative stress and anxiety. Four different doses of the decoction of Ocimum gratissimum were administered to the animals, and their effects were compared with distilled water (10 mL/kg), pilocarpine (360 mg/kg), sodium valproate (300 mg/kg), NaCl 0.9% and diazepam (3 and 0.3 mg/kg). The results showed that administration of Ocimum gratissimum significantly decreases the number and duration of seizures, it increases the latency of status epilepticus and seizures, as well as the seizure score. The decoctate significantly improves the behavioral performance of mice, and inhibits the effects of pilocarpine. This resulted in a decrease in MDA levels, an increase in reduced glutathione levels. A significant increase in GABA levels and a decrease in GABA-transaminase activity were also observed in animals treated with 244 mg/kg. These results suggest that Ocimum gratissimum has anticonvulsant, antioxidant and anxiolytic properties. It could be used as a preventive measure against Temporal Lobe Epilepsy.
Assessment of Trend Pattern of Rice Production in Some Rice Growing States of India
Authors: Kumar Manish , KE Sukhi Gowda , Prakash Gyan , Menon S. Vivek
Published: February 2025

In this paper, the trend pattern of rice production has been examined for some rice growing states of India viz., Punjab, Andhra Pradesh and Uttar Pradesh. The analysis has been carried out by collecting secondary time series data on rice production during the period 2011-2020, and fitting some well-known models viz., linear model, exponential model and cubic model. The trend values have been estimated by fitting the respective models to the concerned time series data. Moreover, the accuracy of the models has been examined using coefficient of determination (), root mean square error (RMSE), and relative mean absolute percentage error (RMAPE). Furthermore, Chi-square test of “goodness of fit” has been applied in the empirical investigation for validation of the concerned fitted models. The results of the investigation reveal the suitability of the models for exploring the scenario of trend patterns of rice production in the concerned states of India.
Evaluation of Novel Broad-spectrum Fungicides for Management of Rice Blast and Sheath Blight under In-vitro and Field Conditions
Authors: Babu T. Kiran , Ramakrishna A. , Aravind K. , Varma N. Rama Gopala , Raju Ch. Damodar , Reddy P. Raghu Rami
Published: February 2025

The present study evaluated the efficacy of eight novel fungicidal treatments against Magnaporthe oryzae (Blast) and Rhizoctonia solani (Sheath blight) under both in-vitro and field conditions. In-vitro efficacy against M. oryzae revealed that, complete pathogen growth inhibition (100%) was exhibited by treatments T2 (Picoxystrobin 7% + Propiconazole 12% EC @ 2.0 ml/L), T3 (Pyraclostrobin 100 g/L @ 2.0 ml/L), T4 (Fluxapyroxad 62.5 g/L + Epoxiconazole 62.5 g/L EC @ 1.5 ml/L), T6 (Propiconazole 20% EC @ 1.0 ml/L) and T7 (Isoprothiolane 40% EC @ 1.5 ml/L) at recommended doses. Whereas, at half-recommended doses, T2 and T3 still maintained high efficacy with inhibition rate of 91.8% and 90.7%. Similarly, for R. solani, treatments T2, T3, T4, T5 and T6 also showed complete inhibition at their recommended doses, while T1 and T7 achieved 82.6% and 91.2% inhibition respectively. At half-recommended doses, T2, T3, T4 and T5 registered the cent per cent inhibition, while T1 and T7 showed 79.2% and 81.9%, respectively. In field trials conducted during kharif, 2020 to 2022 revealed that, the treatment T1 notably reduced sheath blight severity to 36.1%, compared to 61.8% in untreated control and achieved the lowest neck blast severity (6.3%) and realised highest yield (7097 kg/ha) and ICBR (1:7.9), and significantly far surpassing the control yield (5144 kg/ha). The triazole-strobilurins combination demonstrated broad-spectrum efficacy, achieving 62.7% and 18.3% reduction in neck blast and sheath blight respectively compared to standard fungicides. These findings underscore the potential of novel combination fungicides in enhancing disease management and yield while lowering the number of sprays and costs to the rice farmers.
Improving Yield Conversion with Triple Conversion Reactor for Styrene Production from Ethylbenzene
Authors: Hutajulu Febi Tia Maria , Vito Ahista Aushafa , Fakhira Fara , Izzati Dzikrina Sekar
Published: February 2025

Styrene is a critical component in various polymer-based materials, with increasing global demand. Its production primarily involves the catalytic dehydrogenation of ethylbenzene, a process requiring high temperatures and facing challenges like by-product formation. This research aims to enhance the yield conversion of styrene using a triple conversion reactor system. The methodology employs Aspen HYSYS simulation, with thermodynamic considerations guiding the reactor designs and operating conditions. Results indicate that implementing three reactors increased the conversion rate from 96% to 99.9% and achieved 99.5% styrene purity. The study concludes that process optimization significantly improves the efficiency and scalability of industrial styrene production. Copyright © 2025 by Authors, Published by Universitas Diponegoro and BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
TECNOLOGIAS DIGITAIS E A RECONFIGURAÇÃO DA COMUNICAÇÃO TRANSNACIONAL NA EXPERIÊNCIA MIGRATÓRIA VALADARENSE
Authors: Ribeiro Domingos Junior Wilson , Mendes Netto Cristiane , Dani Araújo e Pinto Franco , Siqueira Sueli
Published: February 2025

Este artigo apresenta uma análise do processo de comunicação transnacional à luz das transformações tecnológicas digitais, com ênfase nas dimensões humanas, subjetivas e territoriais. Utilizando uma abordagem qualitativa e o método de História Oral, o material empírico é composto por entrevistas com duas mulheres, com laços familiares de mãe e filha, sendo a filha a pessoa que migrou para os Estados Unidos no ano de 2002 e a mãe a que permaneceu morando no Brasil, em Governador Valadares. A análise teórica integra perspectivas das áreas de comunicação, migração e tecnologia da informação pela abordagem dos estudos territoriais. Para avaliação das entrevistas, foi aplicada a Análise de Conteúdo, tendo como categorias temáticas a evolução das mídias na comunicação e a conexão afetiva e emocional entre mãe e filha. Constatou-se, a partir da experiência vivida pelas participantes do estudo, que a evolução da comunicação e das tecnologias digitais afetou a experiência de migração, com mudanças benéficas nos aspectos emocionais e sociais de vínculo entre as entrevistadas. Na atualidade, por meio das tecnologias digitais, foi observado que novas relações se estabeleceram nos territórios vividos, sendo a interação em tempo real parte do cotidiano de ambas. Dessa forma, a transformação do processo de comunicação, a partir das tecnologias digitais, pode proporcionar uma relação do migrante com a família, mais acessível e atualizada, possibilitando contatos com mais frequência.
Relato Integrado: Nível de Divulgação do Capital Humano das Empresas do Novo Mercado da B3
Authors: Maria Martins Souza Júlia , Ventura dos Santos Neto Aloísio , Bonfim Mariana Pereira , Azevedo Alves Mariana , Mauro Madeiros Velôso Soares José
Published: February 2025

Em virtude da necessidade de divulgação de informações financeiras e não financeiras pelas empresas, foi criado o Relato Integrado, com o intuito de melhorar a qualidade dos reportes, através da publicação da geração de valor das companhias nos diferentes capitais. Um dos importantes capitais apresentado pelas empresas é o capital humano, que consiste na capacidade produtiva dos seres humanos, formado por seus conhecimentos, atitudes e habilidades, que geram resultados em uma economia. O objetivo da pesquisa é analisar o nível de divulgação do indicador-chave (KPI) capital humano, das empresas brasileiras listadas no Novo Mercado, da Brasil, Bolsa, Balcão (B3). Para isso, foi realizada uma análise de conteúdo dos 11 KPI’s do capital humano nos Relatos Integrados de 73 empresas do Novo Mercado, do ano de 2022. Observou-se que, em média, as empresas apresentaram um nível satisfatório (0,63) de disclosure de seus capitais humanos. O indicador-chave mais divulgado pelas empresas foi a quantidade de funcionários, sendo o único indicador com 100% de disclosure, seguido pela média de dias de treinamento (92%) e sobre diversidade (81%). A maioria das empresas corresponderam ao nível satisfatório, o que mostra uma evolução no disclosure das empresas, demonstrando um avanço nas divulgações de informações não financeiras para o mercado. Essa pesquisa se diferencia das demais, dada a especial atenção ao capital humano, principalmente em decorrência da Resolução CVM n° 59/2021, que abrange a necessidade de uma maior quantidade de informações a serem divulgadas, relacionadas ao capital humano das empresas, no Formulário de Referência.
Pesquisadores em Contabilidade no Brasil: análise das parcerias internacionais e fontes de financiamentos por área de competência de role models
Authors: Bortolocci Espejo Márcia Maria dos Santos , Kublik Matheus kevin Mohr , Camargo Aline , Oliveira Andersem Martins de
Published: February 2025

O objetivo do presente estudo é evidenciar o panorama do campo de pesquisa contábil no Brasil no quadriênio 2017-2020, considerando redes internacionais e fontes de financiamento nas áreas de competências de pesquisadores considerados role models na área [pesquisadores pertencentes a 12 Programas de Pós-Graduação Stricto Sensu considerados de excelência e 34 Professores Bolsistas Produtividade em Pesquisa pelo CNPq na área de Ciências Contábeis que não pertencem a estes PPGs]. Metodologicamente, a investigação predominantemente de cunho quantitativo, descritivo e documental, utilizou como base as informações constantes no documento de avaliação quadrienal da área 027 da Capes, bem como dados dos Programas de Pós-graduação constantes em seus sites, dos pesquisadores bolsistas em Produtividade em Pesquisa pelo site do CNPq e informações declaradas nos currículos na Plataforma Lattes dos pesquisadores da área. Os achados apontam 2 áreas de competência principais na Contabilidade: Contabilidade financeira e finanças e Controladoria e Contabilidade Gerencial, relacionadas a 46,6% dos pesquisadores; 44 países realizaram parcerias internacionais com o Brasil na área, destacando-se Inglaterra, Alemanha, Espanha, Canadá e Estados Unidos; 520 projetos foram financiados, sendo sua grande maioria pelo CNPq. Ademais, a presente investigação consolidou um banco de dados com informações de todos os pesquisadores da amostra, que pode servir aos diversos stakeholders da área de Ciências Contábeis.
Features and Factors Associated With Myeloid Neoplasms After Chimeric Antigen Receptor T-Cell Therapy
Authors: Gurney Mark , Baranwal Anmol , Rosenthal Allison , Kharfan-Dabaja Mohamed A. , Kenderian Saad S. , Lin Yi , Shah Mithun Vinod
Published: February 2024

This case-control study examines the incidence and risks of myeloid neoplasms in adults treated for B-cell lymphoproliferative disorders or multiple myeloma.
V2O5 ⋅ nH2O and Graphene Oxide/CNTs Composite Film as Binder‐Free Cathode for Aqueous Zinc‐Ion Batteries
Authors: Rao Diwen , Zhang Wenwei , Cheng Baochen , Wang Yu , Lei Chengsifan , An Qinyou , Huang Meng , Mai Liqiang
Published: February 2024

Emerging as a leading contender for economical, high‐security grid‐scale energy storage, rechargeable aqueous zinc‐ion batteries (AZIBs) are currently facing the challenge in its progression due to the absence of cathode materials with high energy density. In this study, we design a V2O5 ⋅ nH2O, GO and CNTs composite (HVO/GO‐CNTs) film through freeze‐drying and vacuum filtration. This binder‐free cathode for AZIBs exhibits remarkable electrochemical performance, featuring a high capacity of 387 mAh g−1 at 0.2 A g−1 and a high capacity retention of 82.6 % after 1000 cycles at 1 A g−1. This investigation offers a promising approach to electrode material design for the advancement of high‐performance AZIBs.
Diameter estimates in Kähler geometry
Authors: Guo Bin , Phong Duong H. , Song Jian , Sturm Jacob
Published: February 2024

Diameter estimates for Kähler metrics are established which require only an entropy bound and no lower bound on the Ricci curvature. The proof builds on recent PDE techniques for estimates for the Monge–Ampère equation, with a key improvement allowing degeneracies of the volume form of codimension strictly greater than one. As a consequence, we solve the long‐standing problem of uniform diameter bounds and Gromov–Hausdorff convergence of the Kähler–Ricci flow, for both finite‐time and long‐time solutions.
Limited Fat Digestion in Infants with Bronchopulmonary Dysplasia
Authors: Boehm G. , Bierbach U. , Moro G. , Minoli I.
Published: February 2024

In 10 hyaline membrane disease patients with development of bronchopulmonary dysplasia, 16 hyaline membrane disease patients without development of bronchopulmonary dysplasia, and 12 very‐low‐birthweight infants without major medical problems, we measured the lipase and trypsin activity as well as the bile acids concentrations in preprandially aspirated duodenal juice. In addition, fat and nitrogen balances were performed during the 5th and 6th weeks of postnatal life. The mean duodenal lipase activity in the patients with bronchopulmonary dysplasia was significantly lower than those of the patients without bronchopulmonary dysplasia (4.41 ± 3.0 versus 9.95 ± 3.0 U/ml, p < 0.05) and of the controls (19.94 ± 6.8 U/ml). The mean total bile acid concentration was below the critical micellar concentration of 4 mmol/L only in the patients with bronchopulmonary dysplasia. The fecal fat excretion rate in the patients with bronchopulmonary dysplasia was significantly higher than in the patients without bronchopulmonary dysplasia (21.4 ± 4.6% versus 11.3 ± 3.4% of intake, p < 0.01) as well as that of the controls (7.9 ± 2.8% of intake). The serum urea concentrations were similar in the patients without bronchopulmonary dysplasia and in the controls (1.97 ± 0.6 and 1.89 ± 0.4 mmol/L, respectively) but significantly higher in the patients with bronchopulmonary dysplasia (2.54 ± 0.5 mmol/L). The lowest weight gain was found in the patients with bronchopulmonary dysplasia (8.2 ± 4.7 g/kg/day). It was significantly lower than one of the patients without bronchopulmonary dysplasia or the controls (13.5 ± 4.0 and 16.2 ± 3.7 g/kg/day, respectively). The data indicate that patients who develop bronchopulmonary dysplasia have a limited fat absorption, which may help to explain the inadequate weight gain.
Combined Use of Cyclosporine and Azathioprine or 6‐Mercaptopurine in Pediatric Inflammatory Bowel Disease
Authors: Ramakrishna J. , Langhans N. , Calenda K. , Grand R. J. , Verhave M.
Published: February 2024

The aim of this study was to assess whether in steroid‐resistant patients with pediatric inflammatory bowel disease (IBD) a combination of cyclosporine and azathioprine (or 6‐mercaptopurine) could induce remission and subsequently permit maintenance on azathioprine/6‐mercaptopurine as the sole immunosuppressive agent. Two boys and six girls (six with ulcerative colitis and two with Crohn's disease; ages 3‐17 years) received 100‐200 μg/kg/day cyclosporine intravenously and then 4‐10 mg/kg/day orally. Doses were adjusted to achieve trough serum cyclosporine levels of 100‐200μ/L (Abbott's TDX assay). Seven of the eight patients received azathioprine/6‐mercaptopurine, and all were given a 5‐aminosalicylate preparation and corticosteroids. The latter drugs were continued and then tapered off as clinical status allowed. Cyclosporine was continued for 3‐10 months in those who responded. In seven of eight patients, there was a rapid clinical response; one patient showed a transient response, but recurrent bleeding led to total colectomy 9 days after starting cyclosporine. Of the seven responders, three were able to discontinue prednisone and cyclosporine and are doing well on azathioprine at long‐term follow‐up (2‐5 years). One who did not receive azathioprine/6‐mercaptopurine maintained remission for 2 years after cyclosporine was stopped, one experienced a disease flare‐up 5 months after start of cyclosporine treatment and required colectomy, one who did not tolerate 6‐mercaptopurine had a flare‐up during cyclosporine tapering and underwent surgery at 6 months, and one started to flare up with cyclosporine tapering at 6 months and was scheduled for surgery. No significant complications of treatment were observed. Seven patients had an initial response and four of them have so far not required surgery. These preliminary findings suggest that azathioprine/6‐mercaptopurine can be used safely to maintain cyclosporine‐induced remission in children with IBD.
Vitamin E Supplementation in Cystic Fibrosis
Authors: Peters S. A. , Kelly F. J.
Published: February 2024

Vitamin E is an antioxidant and may have a role in the protection of lung tissue against oxidative damage in cystic fibrosis. Previous studies of vitamin E status in cystic fibrosis. Previous studies of vitamin E status in cystic fibrosis have used plasma or serum concentrations, which vary with levels of carrier lipoproteins and hence may not reflect the concentration of vitamin E in tissues, where it is found in highest concentration in membranes. Erythrocyte vitamin E concentration has been shown to correlate well with tissue concentrations of the vitamin in animals, but it has not previously been studied in patients with cystic fibrosis. Current guidelines on vitamin supplementation in cystic fibrosis include vitamin E. It is not presently clear which level of supplementation is most appropriate. To address this question, we examined the effect on erythrocyte vitamin E levels of supplementation with either 15 mg or 100 mg per day of vitamin E. Analysis was performed by high performance liquid chromatography before and 1 year after initiation of supplementation in children with cystic fibrosis. Erythrocyte vitamin E concentrations were below the normal range in almost all unsupplemented patients and rose into the normal range with a supplement of 100 mg per day, but not 15 mg per day. This rise was not accounted for by changes in general dietary treatment. We conclude that tissue vitamin E levels are low in patients with cystic fibrosis who do not receive supplements but can be normalized in most children with 100 mg of vitamin E per day.
Comparison of Oral Sodium Phosphate to Polyethylene Glycol‐Based Solution for Bowel Preparation for Colonoscopy in Children
Authors: Gremse David A. , Sacks Alan I. , Raines Sheree
Published: February 2024

Thirty‐four patients, aged 3 to 17 years, were randomized to receive oral sodium phosphate solution or a polyethylene glycol‐based solution in preparation for elective colonoscopy. Nineteen patients received two doses of oral sodium phosphate solution (45 mL/1.7 m2/dose) and 15 received polyethylene glycol‐based solution (4 L/1.7 m2). Compliance with oral sodium phosphate solution was judged as easy or tolerable in 15 of 19 patients, but only in 5 of 15 who were given polyethylene glycolbased solution. The quality of colon cleansing was rated by an endoscopist who was blinded to the colon preparation method used. The bowel preparation was excellent or good (only liquid remaining in the colonic lumen) in 18 of 19 patients who received oral sodium phosphate solution and in 6 of 15 who received polyethylene glycol‐based solution. The incidence of vomiting was similar in both groups, but abdominal pain occurred more frequently in the polyethylene glycol‐based solution group. Hyperphosphatemia developed in patients who received oral sodium phosphate solution (serum phosphorus = 2.3 ± 0.7 mmol/L (7.2 ± 2.2 mg/dL; mean ± SD), but only in 1 of 15 patients in the polyethylene glycol‐based solution group. Patients did not exhibit symptoms of hyperphosphatemia and serum calcium concentrations were similar in both groups. In summary, oral sodium phosphate solution is better tolerated than polyethylene glycol‐based solution for bowel preparation in children. However, hyperphosphatemia occurred frequently in patients who received oral sodium phosphate solution. Further studies are needed to determine the optimal dose for safety and efficacy for the use of these solutions in children.
Fecal Polyamine Concentration in Children with and without Nutrient Malabsorption
Authors: Forget P. , Sinaasappel M. , Bouquet J. , Deutz N. E. P. , Smeets C.
Published: February 2024

Background:

Fermentation products of malabsorbed nutrients are thought to be responsible for intestinal adaptation following small bowel resection in rats. It has been suggested that either short‐chain fatty acids or polyamines (mainly putrescine and cadaverine) could be the fermentation products involved. There are no data available on fecal polyamine content in humans. The present study compared the fecal polyamine concentrations in children with and without malabsorption.

Methods:

Sixteen (8 girls, 8 boys) malabsorption patients (cystic fibrosis: 13, short bowel syndrome: 2, biliary atresia: 1) with a mean age of 8 years were compared to 17 (9 girls, 8 boys) sick children without malabsorption (mean age 5.7 years). Three‐day fecal collections were performed and analyzed for fat and polyamine concentrations. High‐performance liquid chromatography (HPLC) was used for the measurement of polyamine concentrations.

Results:

Mean and SEM for fecal fat excretion was 13.4 ± 2.5 g/day and 1.5 ± 0.3 g/day in the malabsorption and control group respectively. Median fecal cadaverine and putrescine concentrations were 3723 μmol.kg‐1 feces and 4737 μmol.kg‐1 feces for the malabsorption group and 114 μmol.kg‐1 feces and 306 μmol.kg‐1 feces for the control group (p < 0.007 and < 0.00001 respectively). No significant differences were found for fecal spermine and spermidine concentrations between the two groups.

Conclusions:

Children with malabsorption show very high fecal putrescine and cadaverine concentrations. Our results support the hypothesis that fecal polyamines could be important.
Intra‐ and Interexaminer Reliability of Anthropometric Measurements of Term Infants
Authors: Johnson Teresa S. , Engstrom Janet L. , Gelhar Debra K.
Published: February 2024

Background:

The reliability of anthropometric measurements of term infants has not been studied sufficiently to determine if these measurements are reliable enough to be used in clinical practice and research. This study described the intra‐ and interexaminer reliability of the following anthropometric measurements: weight (WT), head circumference (HC), chest circumference (CC), abdominal circumference (AC), mid‐arm circumference (MAC), and length.

Methods:

A convenience sample of 50 clinically stable term infants was studied. Two examiners obtained the six measurements twice using blank tape measures. The order of examiners was randomized and the examiners were masked to their own and the other examiners' measurements.

Results:

The intraexaminer mean absolute differences were as follows: WT = 1.88, 3.28 g; HC = 0.29, 0.29 cm; CC = 0.50, 0.78 cm; AC = 0.71, 0.77 cm; MAC = 0.36, 0.39 cm; length = 0.92, 1.18 cm. The interexaminer mean absolute differences were as follows: WT = 1.94, 1.66 g; HC = 0.37, 0.36 cm; CC = 0.59, 0.72 cm; AC = 0.99, 0.77 cm; MAC = 0.41, 0.57 cm; length = 1.57, 1.47 cm.

Conclusions:

These findings indicate that intraexaminer differences tended to be smaller than interexaminer differences for all measures except weight, which remained stable for intra‐ and interexaminer comparisons. These findings also suggest that weight and head circumference were the most reliable measures, whereas length and mid‐arm circumference were the least reliable measures.