bluuebunny/crossref_metadata_2025 huggingface dataset:
Necmemini : Performing Forgetfulness in Persius’ Satires
Authors: Moorman Rebecca
Published: February 2025

Abstract: Persius’ Satires operate outside traditional Roman poetic and educational lineages in which knowledge is handed down through patrilineal memory. Persius’ anachronistically pederastic relationship with his teacher Cornutus represents a queer departure from normative time that forgets traditional father figures in favor of alternative kinships and new ways of knowing. Abstract: Les Satires de Perse opèrent à l’extérieur des lignées poétiques et éducatives traditionnelles romaines, où le savoir est transmis à travers la mémoire patrilinéaire. La relation pédérastique anachronique de Perse avec son enseignant Cornutus représente une divergence queer par rapport à la normativité de l’époque, divergence qui abandonne les figures paternelles traditionnelles pour privilégier d’autres types de parenté et de nouveaux modes de savoir.
Simulating long-range atmospheric turbulence in the laboratory with an artificial turbulence simulator
Authors: Tan Wei , Huang Feng , Li Ting , Huang Xianwei , Nan Suqin , Bai Yanfeng , Fu Xiquan
Published: February 2025

Atmospheric turbulence is the predominant propagation medium in random environments, significantly impacting beam propagation, particularly over long distances. In this study, we establish an equivalent experimental setup in the laboratory to simulate long-range atmospheric turbulence. The experiment employs a water tank, a wave maker, and a transparent perforated plate to generate turbulence with predetermined scales. We investigate the behavior of a laser beam propagating through a random environment induced by water flow from various directions. The scintillation index and RMS displacement of the beam’s hot spot at the receiver are utilized to characterize the influence of water turbulence on light intensity fluctuations and beam wander, respectively. By inverting the intensity of water turbulence based on scintillation index and beam wander measurements, we observe an error magnitude less than one order of magnitude between them. Compared to atmospheric turbulence, our laboratory-generated water turbulence is four orders of magnitude stronger. This work establishes an equivalent connection between atmospheric turbulence and water turbulence, enabling realistic simulation of long-range laser propagation under actual atmospheric conditions.
“They organized women who advised me”: Adolescents’ perceptions of Social and cultural influences on mental health during the postnatal period in Malawi: Qualitative study
Authors: Tembo Chimwemwe , Portsmouth Linda , Burns Sharyn
Published: February 2025

The postnatal period is a critical transition period for first-time mothers, especially adolescents. An indication of maladaptation with this transition is the experience of poor mental health by some adolescent mothers. Social and collective cultural factors have been claimed to influence maternal mental health during the postnatal period; however, there is limited research focusing on cultural and social factors that influence adolescents’ mental health during the postnatal period in rural Malawi. Therefore, we explored the perceived cultural and social factors that influence mental health among adolescent mothers during the postnatal period in rural Malawi. A descriptive qualitative design (DQ) was employed. Data were collected from September 7th, 2021, to March 31st, 2022, from a convenience sample of 395 adolescent mothers. Reflexive thematic analysis was employed using open coding. Codes were grouped into categories and themes derived using inductive thinking. Adolescent mothers’ mental health was found to be influenced by interactions between social and cultural factors within all levels of the Social Ecological Model of Health (SEM). Four main themes, health and mental health awareness, relationships, family support, and rite of passage, explained social and cultural influences for adolescent mothers in Malawi. There is a need for collaborative, coordinated, and co-designed efforts to implement integrated, comprehensive, and culturally appropriate interventions at each level of SEM influence to promote adolescent’ mothers’ mental health. Specifically, policies should focus on the prevention of early marriages, improved access to reproductive health services, and long-term interventions to promote family involvement in the care of mothers. Healthcare systems should offer accessible mental health support for adolescent mothers.
What determines investment in the Nippon Individual Savings Account? an investigation of Japan’s tax-exempt investment account
Authors: Katauke Takuya , Khan Mostafa Saidur Rahim , Kadoya Yoshihiko
Published: February 2025

In 2014, the Japanese government introduced the Nippon Individual Savings Account (NISA) to encourage tax-exempt investment and asset accumulation. In January 2024, the NISA underwent significant restructuring to boost household savings in financial asset investments. Taking advantage of the launch of the revamped NISA, we analyzed data collected in late 2022 of 95,632 active investors in a leading securities company to explore their preferences in the previous NISA. Notably, investors exhibit a preference for installment NISA over ordinary NISA, indicating an inclination for long-term capital establishment through gradual investments in secure financial assets. Regression analysis reveals that installment NISA investors are typically female, older, married, or divorced, have lower educational qualifications, engage in part-time employment, have higher incomes, display risk aversion, maintain larger asset balances, and adopt long-term perspectives. By contrast, those favoring ordinary NISA tend to be male, young, married, and financially literate and to have lower incomes, higher asset balances, and shorter-term perspectives. This study advocates maintaining both NISA types, increasing the annual and total investment limits, and eliminating tax exemption periods. These measures would be advantageous for tax savings and capital formation. However, a robust financial education campaign is emphasized to encourage individuals to invest in financial assets, breaking the tradition of keeping funds idle.
Digital economy, green finance, and economic resilience
Authors: Zhang Jianqi
Published: February 2025

With the rapid development of digital technology, the digital economy has become an important force to promote economic growth and drive innovation, and to enhance economic quality and ecological efficiency through green finance. Additionally, green finance, as an important means to achieve resource and environmental sustainability, has received increasing attention and importance from the international community. This study explores how the digital economy and green finance contribute to economic resilience using panel data from 30 provinces and cities in China from to 2011–2023. The development of the digital economy can effectively promote economic resilience, and green finance plays a significant mediating role between the digital economy and economic resilience. In this regard, China’s economic resilience must be enhanced by strengthening the construction of digital infrastructure, promoting innovation and the development of green finance, and formulating a policy environment conducive to the development of green finance.
Representations of changing weather conditions and outdoor work in the Swedish media: Legitimization of a risk discourse
Authors: Nilsson Bo , Lönnroth Jenny
Published: February 2025

Accelerating climate change has been associated with, among other things, rising temperatures, rising sea levels, extensive periods of precipitation, and difficult wind conditions. These are said to affect large segments of society, not least outdoor workers, whose working conditions are negatively affected. Much media attention has been paid to the situation of outdoor workers, and the media presents tips on what to consider when working in conditions such as high temperatures. The aim of this paper is to explore how the Swedish media reports on outdoor workers and their working conditions in relation to climate change and difficult weather conditions, especially high temperatures. The aim is also to describe and analyze how an identified risk discourse is legitimized in media representations of extreme weather and outdoor work. The study is based on a qualitative analysis of 72 articles in the Swedish media, available in the digital archive retriever.com (Mediearkivet). A social constructionist perspective is used to explore how weather, climate, and risks are “constructed” in the material, and a focus on storytelling techniques and legitimization strategies makes it possible to investigate how certain views of weather, climate, and risks are justified. According to the results, climate change and changing weather conditions are related to risks at both a structural level and an everyday level in working life. Two overall categories of risk are identified, on one side physiological and mental risks, and on the other economic and technological risks. Together, these categories underpin a general risk discourse that is legitimized using strategies such as scientification, dramatization, and personification. The conclusion is that the media representations are characterized by a de-politization of climate change and changing weather conditions, and by a focus on individual adaptation to these changes.
Underwater paleontology inside cenotes reveals the Miocene-Pliocene fish diversity in the Yucatan Peninsula, southeast Mexico
Authors: Cantalice Kleyton M. , Salgado-Garrido Hugo E. , Sosa-Rodríguez Erick , Vilchis-Zapata Kay , González-Barba Gerardo ,   on behalf of the Underwater Archaeological Atlas project
Published: February 2025

The Yucatan Peninsula, southeast México, hosts a unique underwater karstic system of galleries connected by multiple sinkholes, locally called cenotes. This system is developed on a great Late Miocene to Early Pliocene carbonate platform belonging to the Carrillo Puerto Formation. The karstification process partially erodes these deposits’ surfaces and exposes the fossil assemblage. Here, we present the fossil fish diversity in underwater prospections in the Cenotes Sambulá, San Juan, and X-Nabuy. Our results indicate the presence of at least 11 different taxa, which include: 1) species that live today on Mexican coasts, such as Carcharhinus brachyurus, C. leucas, C. perezii, Carcharodon carcharias, and unidentified Rhinoptera species; 2) extinct taxa, such as †Galeocerdo mayumbensis, †Hemipristis serra, and †Otodus (Carcharocles) megalodon; 3) taxa that are not currently distributed in Mexican coasts, such as Carcharhinus macloti and representatives of the genus Aetomylaeus. Furthermore, a new Diodontidae species, †Chilomycterus dzonotensis sp. nov., is described. It represents an increment in the Neogene fish diversity in the Gulf of Mexico and supports a shallow marine environment associated with a coral reef system. The small size of some teeth indicates that the deposits of Carrillo Puerto could be a shelter for tiny marine organisms, and the presence of some taxa highlights local extinctions in the Western Atlantic during the Late Cenozoic.
TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep
Authors: Qiu Li-Xia , Yu Qian , Zhou Hua-Qian , Fan Wen-Hua , Zheng Jing-Jing , Yang Yong-Lin , Zhang Wen-Zhe , Cao Xin , Yang Hua
Published: February 2025

The development of secondary hair follicles influences the quality of sheep wool. However, the mechanism by which proteins mediate the fetal development of secondary hair follicles remains unknown. In this study, the histomorphology of secondary hair follicles was analyzed over four stages of fetal development (75, 85, 95, and 105 gestational days). TMT-based quantitative proteomics was used to compare the differential protein profiles of skin tissues between consecutive developmental periods (75 versus 85, 85 versus 95, and 95 versus 105 gestational days). We found that the density of secondary hair follicles and the secondary hair follicles/primary hair follicles ratio increased from 85 to 105 gestational days. Bioinformatic analysis identified 238, 35, and 348 differentially expressed proteins in the respective comparison periods. Focal adhesion, ECM−receptor interaction, and the estrogen signaling pathway all played important roles in secondary hair follicle development. COL1A1, THBS3, ITGA6, COL6A1, and THBS4 were identified as potential candidate proteins in the initiation of secondary hair follicles. This study provides valuable proteomics data on secondary hair follicle development and thus has deepened our understanding of the molecular mechanisms underlying wool quality traits in fine-wool sheep.
Quality of information in gestational diabetes mellitus videos on TikTok: Cross-sectional study
Authors: Jiang Genyan , Chen Lei , Geng Lan , Zhang Yuhan , Chen Zhiqi , Zhu Yaqi , Ma Shuangshuang , Zhao Mei
Published: February 2025

Background

TikTok is an important channel for consumers to obtain and adopt health information. However, misinformation on TikTok could potentially impact public health. Currently, the quality of content related to GDM on TikTok has not been thoroughly reviewed.

Objective

This study aims to explore the information quality of GDM videos on TikTok.

Methods

A comprehensive cross-sectional study was conducted on TikTok videos related to GDM. The quality of the videos was assessed using three standardized evaluation tools: DISCERN, the Journal of the American Medical Association (JAMA) benchmarks, and the Global Quality Scale (GQS). The comprehensiveness of the content was evaluated through six questions covering definitions, signs/symptoms, risk factors, evaluation, management, and outcomes. Additionally, a correlational analysis was conducted between video quality and the characteristics of the uploaders and the videos themselves.

Results

A total of 216 videos were included in the final analysis, with 162 uploaded by health professionals, 40 by general users, and the remaining videos contributed by individual science communicators, for-profit organizations, and news agencies. The average DISCERN, JAMA, and GQS scores for all videos were 48.87, 1.86, and 2.06, respectively. The videos uploaded by health professionals scored the highest in DISCERN, while the videos uploaded by individual science communicators scored significantly higher in JAMA and GQS than those from other sources. Correlation analysis between video quality and video features showed DISCERN scores, JAMA scores and GQS scores were positively correlated with video duration (P<0.001). Content scores were positively correlated with the number of comments (P<0.05), the number of shares (P<0.001), and video duration (P<0.001).

Conclusion

We found that the quality of GDM video on TikTok is poor and lack of relevant information, highlighting the potential risks of using TikTok as a source of health information. Patients should pay attention to identifying health-related information on TikTok.
Pre-siting of UAV stations for traffic accident assessment considering road dispersion
Authors: Wang Sizhe , Shang Yanying
Published: February 2025

This paper investigates the issue of pre-site selection for drone stations with the aim of enhancing the rapid assessment capability of urban road traffic accidents. Firstly, the influence of traffic accidents on urban traffic is analyzed, and the potential application of drones in rapid response at the accident scene is explored. A minimization model is constructed with the goal of minimizing the cost of accident handling and reducing traffic congestion. To solve this problem, we improved the simulated annealing algorithm by combining the multi-neighborhood strategy, adaptive neighborhood size, and adding a taboo list, and verified the effectiveness of the algorithm. The validity of the model is tested through simulation examples, and the impact of the drone coverage radius and the distribution of accident points on the model performance is explored through sensitivity analysis, providing management insights for the pre-site selection of drone stations.
Machine learning identifies the association between second primary malignancies and postoperative radiotherapy in young-onset breast cancer patients
Authors: Lai Yulin , Huang Peiyuan
Published: February 2025

Background

A second primary malignant tumor is one of the most important factors affecting the long-term survival of young women with breast cancer (YWBC). As one of the main treatments for breast cancer YWBC patients, postoperative radiotherapy (PORT) may increase the risk of second primary malignancy (SPM).

Methods

Machine learning components, including ridge regression, XGBoost, k-nearest neighbor, light gradient boosting machine, logistic regression, support vector machine, neural network, and random forest, were used to construct a predictive model and identify the risk factors for SPMs with data from the Surveillance, Epidemiology and End Results. Multivariate logistic regression analysis was used to assess the risk of SPM associated with PORT. The cumulative incidence of SPMs was determined by competing risk regression analysis.

Results

Among the 44223 YWBC patients included in our study, 3017 developed SPMs. Among all the clinical characteristics, PORT was the most common SPM. YWBC patients receiving PORT had significantly greater risks of second primary solid malignancies (SPSMs, RR = 1.61), including breast cancer (RR = 1.89), lung cancer (RR = 2.12) and thyroid cancer (RR = 1.48), but not second primary hematologic malignancies (RR = 1.32; 0.94–1.88). SPSMs were more common in YWBC individuals who were black, had a lower median household income and had fewer lymph nodes examined. Additionally, we developed a prediction nomogram with an area under the curve of 0.75 to assess the likelihood of developing SPMs.

Conclusion

YWBC patients receiving PORT had a greater risk of developing SPSMs (thyroid, lung, and breast cancer), indicating the necessity of long-term surveillance of these patients. Standard adjuvant PORT should not be recommended for breast cancer patients with favorable histology and a low risk of relapse.
Association between serum albumin levels and erectile dysfunction in American Adults: A cross-sectional study from NHANES 2001–2004
Authors: Wen Haibin , Lan Zhenyu , Liang Xueming , Su Huabin , Qin Yuqi
Published: February 2025

Background

The aim of this study is to investigate the association between Serum Albumin Levels (ALB) and erectile dysfunction (ED) within the U.S. general population.

Methods

We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES) 2001–2004 cycles. Serum albumin was analyzed both as a continuous variable and categorized into quartiles. Erectile dysfunction (ED) was assessed via self-reported questionnaires. The association between serum albumin and erectile dysfunction was evaluated using weighted logistic regression models across four models: (1) Crude model (unadjusted); (2) Model 1: Adjusted for age, race, poverty-to-income ratio (PIR), marital status, education level, and body mass index (BMI); (3) Model 2: Adjusted for factors in Model 1 plus physical activity, smoking status, drinking status, and Healthy Eating Index (HEI-2015); (4) Model 3: Adjusted for factors in Model 2 plus remaining potential covariates. A generalized additive model (GAM) was employed to examine non-linear associations, followed by subgroup analyses and interaction tests.

Results

A total of 2925 participants were included in the study, of which 747 were diagnosed with ED. After adjusting for all covariates, a significant negative association was found between ALB and ED (OR: 0.53, 95% CI: 0.29–0.97, P = 0.04). Higher ALB quartiles were significantly correlated with a decreased risk of ED [Q4 vs. Q1: OR: 0.56 (0.35–0.90), P =  0.02; P for trend =  0.03]. The GAM and smoothed curve fit indicated a linear relationship between ALB and the risk of ED. Stratified and interaction tests further substantiated the inverse relationship between ALB and ED prevalence.

Conclusions

This study revealed an inverse association between ALB and ED. Therefore, it is important for clinicians to recognize the assessment of ALB in patients.
Immediate and short-term effects of neurodynamic techniques on hamstring flexibility: A systematic review with meta-analysis
Authors: Núñez de Arenas-Arroyo Sergio , Martínez-Vizcaíno Vicente , Torres-Costoso Ana , Reina-Gutiérrez Sara , Bizzozero-Peroni Bruno , Cavero-Redondo Iván
Published: February 2025

Background

Good hamstring flexibility(HF) is crucial for sports performance and health, with injuries having an economic impact on healthcare and sports teams. Therefore, our objectives were to estimate the effect of neurodynamic techniques on HF and to compare the effect of these techniques with static stretching.

Methods

We systematically searched the Cochrane, MEDLINE(via PubMed), Scopus, Web of Science and Sportdiscus databases for RCTs comparing neurodynamic interventions with control intervention or with static stretching exercises for HF in adults with limited HF. We conducted a random-effects meta-analysis with subgroup analyses according to the type of comparison group(control group or static stretching exercises) and total number of sessions. Furthermore, to reflect the variation in genuine therapy effects in different scenarios, including future patients, we calculated a 95% prediction interval(prI).

Results

Thirteen trials were included, involving 624 participants. Pooled results showed a significant improvement in HF for immediate (SMD = 1.01, 95% CI: 0.44 to 1.59) and short-term effects (SMD = 1.21, 95% CI: 0.90 to 1.52). Subgroup analyses by type of comparison group showed that these techniques are more effective than the control group in the immediate and short term and than static stretching in the short term. Analyses by total sessions showed a significant increase in HF with a treatment of 1, 3, 10 and 12 sessions.

Conclusion

Neurodynamic techniques improve HF immediately and in the short term. Subgroup analyses by type of comparison group showed that these techniques are more effective than static stretching in the short term.
Insight into the mechanical properties and the sustainable application of recycled permeable concrete: Green low-carbon concrete technology
Authors: Xia Shaojian , Peng Lei , Zhang Wu , Zhu Hongliang , Li Jing
Published: February 2025

The performance optimization of reclaimed permeable concrete helps to reduce the energy consumption of building materials preparation and promotes green and sustainable development. To further adjust the ratio of reclaimed permeable concrete and optimize the mechanical properties of reclaimed permeable concrete, the influence of aggregate particle size distribution on the mechanical properties of reclaimed permeable concrete is analyzed. In the analysis of the effect of particle size distribution on the mechanical properties of recycled aggregate permeable concrete, the design experiment was examined. The experiment showed that when the water-cement ratio was 0.28/0.30/0.32 and the porosity was 10%, the increase in permeability coefficient was 28.1%/50.9%/29.0%. When the recycled permeable concrete had a water-cement ratio of 0.30 and a particle grading of 8:2 at a target porosity of 10%, the average permeability coefficient was the lowest, only 1.23mm/s. The circulating permeable concrete of the study design met the requirement of the permeability coefficient under the CJJ/T1352009 standard, which was not less than 1 mm/s. The extant research on the influence of aggregate grading and other parameters on the performance of recycled permeable concrete indicates that the ratio of recycled aggregate permeable concrete can be optimized. Furthermore, the customization of concrete ratio according to the needs of different buildings can effectively reduce the manufacturing cost of building materials.
Investigation of injury severity level in truck-related crashes at school zones using mixed generalized ordered models
Authors: Cho Junhan , Lee Sungjun , Park Juneyoung
Published: February 2025

The number of truck registrations is steadily increasing in Korea. The proportion of truck deaths compared to the total number of traffic crashes was 23.9%, which is significantly higher than that of other vehicles. In the field of traffic safety, the Children’s Safety Measures Policy by government aims to enhance the safety of children’s commuting routes by expanding school zones. Nonetheless, truck crashes continue to occur in school zones. Therefore, this study analyzed the factors that affect the severity of truck traffic crashes in school zones in order to contribute to safety improvements. In the study, a distinction is made between various levels of severity to determine the factors that contribute to each level. The generalized ordered models were applied to investigate injury severity levels. Moreover, in order to account for heterogeneity issue, the mixed-effects models with random parameters were used for the analysis. These models were constructed using data collected from school zones over a period of recent ten years. The results showed that crashes occurred at night and on the weekend, as well as human factors such as the age of the victim and the gender of the offender, the types of vehicles involved, and the road type, have been identified as important factors contributing to crash severity. By considering the factors that contribute to truck crashes in school zones, it is anticipated that road safety can be enhanced.
Dry eye disease treatment improves subjective quality-of-life responses in patients with AMD, independent of disease stage
Authors: Mehta Nehal Nailesh , Nagel Ines D. , Agnihotri Akshay , Heinke Anna , Cheng Lingyun , Bartsch Dirk-Uwe , Freeman William R. , Gomez Maria-Laura
Published: February 2025

Purpose

To determine the impact of severity of age-related macular degeneration (AMD) on subjective treatment response in patients treated for dry eye disease.

Methods

A total of 203 eyes diagnosed with evaporative dry eye disease (DED) due to meibomian gland dysfunction were treated using the LipiFlow or MiBoFlo systems. From this cohort, 40 eyes with stable dry AMD (early, intermediate, or late stages) were included. Each participant completed the Ocular Surface Disease Index (OSDI) and Standard Patient Evaluation of Eye Dryness Questionnaire (SPEED) before treatment and at a 6-month follow-up. Changes in questionnaire scores were analyzed using one-way analysis of variance (ANOVA) to assess differences between AMD severity groups.

Results

Improvement in SPEED and OSDI scores, including vision related OSDI scores were observed across all AMD stages, with no significant differences between groups (p<0.05).

Conclusion

Managing DED improved quality of life (QOL) in patients with AMD, regardless of retinal disease severity. This highlights the importance of treating coexisting ocular surface conditions to enhance patient outcomes, even in the presence of significant maculopathy.
Induction of systemic resistance through calcium signaling in Arabidopsis exposed to air plasma-generated dinitrogen pentoxide
Authors: Sasaki Shota , Iwamoto Hiroto , Takashima Keisuke , Toyota Masatsugu , Higashitani Atsushi , Kaneko Toshiro
Published: February 2025

Plasma technology, which can instantaneously transform air molecules into reactive species stimulating plants, potentially contributes to developing a sustainable agricultural system with high productivity and low environmental impact. In fact, plant immunity activation by exposure to a reactive gas mainly consisting of dinitrogen pentoxide (N2O5) was recently discovered, while physiological responses to N2O5 are rarely known. Here, we demonstrate early (within 10 min) physiological responses to N2O5 gas in Arabidopsis. Exposure to N2O5 gas induced an increase in cytosolic Ca2+ concentration within seconds in directly exposed leaves, followed by systemic long-distance Ca2+-based signaling within tens of seconds. In addition, jasmonic acid (JA)-related gene expression was induced within 10 minutes, and a significant upregulation of the defense-related gene PDF1.2 was observed after 1 day of exposure to N2O5 gas. These systemic resistant responses to N2O5 were found unique among air-plasma-generated species such as ozone (O3) and nitric oxide (NO)/nitrogen dioxide (NO2). Our results provide new insights into understanding of plant physiological responses to air-derived reactive species, in addition to facilitating the development of plasma applications in agriculture.
Efficacy of acupuncture in treating chemotherapy-related cognitive impairment in breast cancer patients: A systematic review and meta-analysis protocol
Authors: Liu Lishi , Meng Zihan , Yan Jun
Published: February 2025

Background

Chemotherapy-related cognitive impairment (CRCI) is a common adverse effect of chemotherapy in breast cancer patients, with a high incidence that significantly impacts treatment adherence and quality of life. Currently, there is no definitive and effective treatment for CRCI. Research indicates that acupuncture may serve as a promising intervention for CRCI. This study aims to assess the effectiveness of acupuncture in treating CRCI.

Methods

This study is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P). From the time of database construction to October 2024, we will search seven literature databases, three clinical study registry databases, and three sources of gray literature. The restricted languages are English and Chinese. We will use the Participants-Interventions-Comparators-Outcome-Conclusion-Study Design (PICOS) criteria to identify included studies and the RoB2 tool to assess the quality of the included studies. Data synthesis and meta-analysis will be performed using RevMan 5.3.

Discussion

The results of this study will clarify the potential benefits of acupuncture in the treatment of CRCI and address existing disagreements about its efficacy. Furthermore, the findings will assist clinicians in making informed decisions regarding the treatment of CRCI.

Trail registration

PROSPERO registration number: CRD42024568093.
An Unusual Case of Intrahepatic Stone Masquerading as Cholangiocarcinoma
Authors: Williams Alexander S. , Sikes Michael A. , Liu Scott
Published: February 2025

A cancer of the biliary tree, cholangiocarcinoma (CCA) often presents with painless jaundice, right upper quadrant abdominal pain, and unintended weight loss. Serologic testing to include cancer antigen 19-9 (CA 19-9) is elevated in CCA but can also be elevated in inflammatory processes in the biliary system. Diagnosis is difficult and even with advanced imaging techniques false-positives may occur. We present a case of a patient with elevated CA 19-9 and biliary stricture concerning for CCA but was due to hepatic stone. It demonstrates the challenge of correctly diagnosing CCA and an instance of nonmalignant elevation of CA 19-9.
Reexamining the Credibility of the Joseph Schacht Concept of Sanad Hadith
Authors: Ahmad Ubaidillah Ma'sum Al Anwari  , Muhammad Iqbal Trenggono  , Muhammad Fahrul Asyahudi
Published: February 2025

Joseph Schacht, through the book The Muhammadan Jurisprudence, raises a criticism of sanad which considers that hadith did not start from the Prophet, but from tabi'in. It's just that Schacht's concept is considered weak because he is inconsistent and forgets a lot of data and important aspects in the study of hadith. This article appears as the author's attempt to explain the concepts promoted by Schacht and also some of the problems carried out by Schacht. With the help of the descriptive-analytical method combined with a comparison of experts' arguments as a medium of analysis, it can be seen how gaps emerge in Schacht's attitude. The results of the analysis explain that the Schacht controversy is related to; first, Schacht's rejection of the hadith which is not in line with the data of the companions which are part of the hadith; secondly, the theory built by Schacht can be said to be very weak, because much of the data found refutes Schacht's hypothesis; third, there is subjectivity in the use of data and analysis results; and fourth, Schacht, who is known as an expert in Islamic law, should study hadith, but he does not believe that hadith comes from the Prophet.
Advancements in genetic circuits as part of intelligent biotherapy for the treatment of bladder cancer: A review
Authors: Liu Chu , Lu Junlin , Lai Jiajian , Jie Kaiwen , Lin Tianxin , Wang Haifeng , Chen Xu
Published: February 2025

Background: Bladder cancer poses a significant threat to human health. In recent years, genetic circuit therapy has emerged as a novel alternative for precision tumor treatment, demonstrating promising potential for clinical application. Compared to traditional drugs, genetic circuits – typically carried by plasmids – offer advantages such as modularity, druggability, and shorter drug development cycles. These circuits can identify multiple molecular signals from tumors and integrate them through logic gates to specifically target tumor cells. Furthermore, by assembling effector modules, they can induce specific forms of cell death in tumor cells or alter malignant phenotypes, thereby reshaping the immune microenvironment to produce efficient, durable, and controllable antitumor effects. The urinary system serves as an ideal model for this new therapy due to its accessibility from the outside. Several genetic circuits have already been validated for the treatment of bladder cancer. This review outlined the effectiveness and potential value of genetic circuits in bladder cancer therapy. Objective: This review focused on the design principles of genetic circuits, their ability to recognize and convert signals, their therapeutic signal output, and the associated delivery vehicles. We also discussed the challenges and future prospects of genetic circuits as a novel form of “intelligent biotherapy.” Conclusion: The gene circuit can identify multiple signals, processing complex information, and generating multiple effects, thus providing a new approach for personalized treatment of tumors.
Contribución al estudio del género Fuirena (Cyperaceae) en Argentina
Authors: Reutemann Andrea , San Martin Juca A. B. , López M. Gabriela
Published: February 2025

Fuirena (ca. 55 especies) es un género tropical a templado cálido, con centros de diversidad en África y América. En Argentina está representado por tres especies y una forma. En este trabajo se realiza el tratamiento del género Fuirena para Argentina. Se describe e ilustra una nueva especie históricamente confundida con F. incompleta Nees, Fuirena truncata Reutemann & M. G. López. Se comparan los caracteres diagnósticos que permiten diferenciar a F. truncata de F. incompleta, y se proporciona información sobre su distribución geográfica. Se incluye a F. incompleta Nees f. glabra Maury bajo la sinonimia de F. incompleta, y se designan lectotipos para F. incompleta y F. incompleta f. glabra. Se proporciona una clave actualizada para diferenciar a las cuatro especies de Fuirena reconocidas en este estudio para Argentina. Finalmente, se discute el valor taxonómico de la anatomía foliar y caulinar para las especies argentinas de Fuirena.
Starfruit (Averrhoa carambola L.) jam enriched with different types of sugar: A comparative study
Authors: Apolonio K B M
Published: February 2025

This study used an experimental research design. The study was conducted to develop food products using starfruit as the main ingredient and to determine the nutritional composition of starfruit jam. Fifty respondents evaluated the starfruit jam through organoleptic criteria such as appearance, aroma, flavor, consistency, taste, aftertaste, and overall acceptability; a 9-point hedonic scale was used to determine the level of acceptability. This study included three treatments using varying types of sugar, such as white (treatment 1), brown (treatment 2), and muscovado (treatment 3), with the same measurements of ingredients generally acceptable as a result. Treatment 2 has the highest overall acceptability, followed by Treatment 3, and the least is Treatment 1, which are all described as very much by the respondents. Additionally, treatment 2 is the most preferred product regarding taste and aftertaste, while the different age groups have diverse acceptability levels when the food product was evaluated. Starfruit jam was analyzed, and its various nutritional content was determined to ensure that it is healthy and nutritious when consumed. Furthermore, the economic value of starfruit jam provides high investment returns due to the province's availability and affordability of supply. Finally, a potential source of income and product commercialization was forecasted for this newly developed foodstuff.
Przekraczanie granic odmian językowych w regionalnym słowniku tematycznym
Authors: Osowski Błażej
Published: February 2025

Współczesna sytuacja na polskiej wsi doprowadziła do wytworzenia się kodu mieszanego (języka mieszkańców wsi), który zawiera w sobie elementy tradycyjnej gwary, ale także języka potocznego, specjalistycznego i inne. W praktyce leksykograficznej możliwe są dwa podejścia do obserwowanego wewnętrznego zróżnicowania języka wsi. Podejście dyferencyjne zakłada rejestrowanie jedynie słownictwa gwarowego, podejście pełne zaś – rejestrowanie całego zasobu słownego używanego na wsi. Celem artykułu jest zaprezentowanie, w jaki sposób obecność różnych odmian języka na wsi odbija się w budowie słownika regionalnego. W zakresie makrostruktury uwagę zwrócimy na dobór haseł, natomiast w zakresie mikrostruktury słownika – na cytaty. Za przykład posłuży materiał zebrany do przygotowywanych słowników z okolic Konina, ponieważ jednym z głównych założeń tej publikacji jest prezentowanie szerokiego materiału językowego.
Regionalna leksyka kulinarna z Podlasia i Suwalszczyzny we współczesnej przestrzeni publicznej
Authors: Rembiszewska Dorota Krystyna
Published: February 2025

W tekście omówiono nazwy potraw obecne w przestrzeni publicznej Podlasia i Suwalszczyzny – jadłospisach, stronach internetowych, regionalnych przewodnikach i książkach kucharskich. Analizie poddano wyrazy będące regionalizmami, mikroregionalizmami, które znane są mieszkańcom omawianych regionów oraz quasi-regionalizmy rozpoznawane w innych częściach Polski. Istotnym zagadnieniem będzie także kwestia kontaktów językowych w północno-wschodniej Polsce i wpływu języków wschodniosłowiańskich, języka litewskiego, jidysz, tatarskiego na kształtowanie się zasobu leksykalnego w zakresie kulinariów – języków, których refleksy przetrwały do dziś w języku lokalnym.
Medzijazykové kontakty slovenského a nemeckého jazyka na príklade sémantickej analýzy karpatizmov putňa a putera
Authors: Slobodová Zuzana
Published: February 2025

Predmetom štúdie je sémantická analýza karpatizmov putňa a putera v kontexte jazykových kontaktov a interferencie v rámci karpatského areálu s dôrazom na slovensko-nemecké jazykové kontakty. Hlavným cieľom príspevku je podrobiť vybrané karpatizmy analýze s dôrazom na ich sémantickú štruktúru a etymológiu. V rámci sémantickej analýzy sme skúmané karpatizmy rozčlenili na klasifikačné, identifikačné a špecifikačné príznaky. Na základe viacnásobného overenia pôvodu vybraných karpatizmov v domácich a zahraničných publikáciách sme zistili, že oba karpatizmy sú nemeckého pôvodu.
Postnatal enteral plasma supplementation following birth asphyxia increases fluid retention and kidney health in newborn pigs
Authors: Zhong Jingren , Pankratova Stanislava , Doughty Richard , Flyger Christoffer Kirkelund , Sangild Per Torp , Skovgaard Kerstin , Jensen Henrik Elvang , Nguyen Duc Ninh , Thymann Thomas
Published: February 2025

Birth asphyxia can result in kidney dysfunction, disturbances in systemic electrolytes and fluid balance in newborns. Currently, there is no proven dietary approach to support asphyxiated newborns. This study investigates whether oral plasma supplementation improves kidney function and overall health in asphyxiated newborns. Cesarean‐delivered near‐term pigs with or without an 8 min intrauterine clamping of the umbilical cord were fed a milk replacer dissolved in water for 24 h in Experiment 1. Pigs were fed 72 h with milk replacers dissolved in either maternal plasma or water in Experiment 2. Blood, urine, and kidney tissue were collected for further analyses. Asphyxia disrupted blood electrolyte balance. And plasma feeding led to higher fluid retention for both asphyxiated and control pigs. Additionally, plasma feeding may also affect kidney development and protect kidneys from asphyxia induced impairments. Birth asphyxia in pigs led to immediate disturbance of electrolyte balance, impaired fluid retention, and kidney impairments. Plasma feeding may improve postnatal newborn hydration and may also improve the condition of kidneys following asphyxia.
Materialismus im feministischen und queeren Denken
Authors: Möser Cornelia
Published: February 2025

In view of the increasing social and economic inequality in recent decades, both globally and locally, more and more attempts are being made in political philosophy to understand social structures not only in terms of their symbolic and idealistic constitution, but also in the light of their underlying political-economic foundations. However, the concepts of materialism used in these works, especially in feminist thought over the last ten years, have caused much confusion due to their different meanings, especially when they are considered transnationally. This article discusses the numerous publications on materialism in feminist and queer thought and situates them in their respective contexts of origin. Their analysis is then placed in a broader context of philosophical debates on materialism in order to gain a better understanding of the dynamics at play but also in order to better grasp the contributions of feminist and queer thought to the philosophical study of materialism.
When Less Means More: Policy Accumulation, Administrative Capacities, and Policy Performance
Authors: Fernández-i-Marín Xavier , Hinterleitner Markus , Knill Christoph , Steinebach Yves
Published: February 2025

Democratic governments have consistently introduced new policies to address various societal, economic, and environmental issues. However, this ongoing expansion of policy measures risks overburdening the public administrations responsible for their execution. To explore this challenge, we examine how the relationship between the size of sectoral policy portfolios and available implementation capacities impacts the effectiveness of sectoral policies. Our analysis of environmental policies across OECD countries reveals a growing disparity between the number of policies requiring implementation and the resources available to carry them out, which in turn negatively affects policy performance.
Left-peripheral bottom line sequences
Authors: Pinson Mathilde
Published: February 2025

The N-is construction has evolved from main clause to parenthetical, and bottom line has even become a mobile marker. The spoken section of COCA shows that left-peripheral bottom line can be surrounded by other extra-clausal expressions compatible with its pragmatic functions (projection, summation/(sub)topic shift, emphasis, epistemic endorsement and objectification). The aim of this paper is to establish whether these categories exhibit ordering preferences. The study reveals that the left periphery can be divided into nine optional slots. The first four slots usually express disjunction with the previous utterance; they include turn-initiators, then discourse connectors, then markers of disalignment, and then attention-getters/(sub)topic shifters. The second part of the left periphery (Slots 5–9) is more argumentative. The fifth slot comprises subjectifiers: expressions of viewpoint meant to attenuate the peremptory tone of bottom line, which occupies the sixth slot. The seventh slot is filled by the stance-marking discourse marker though, and the eighth slot is typically composed of expressions which de-subjectify the upcoming assertion. Finally, the ninth slot is occupied by addresses, which can be used strategically to maintain the recipient in an inferior interactional position. Together, these expressions form powerful rhetorical devices meant to convince interlocutors while preserving their faces.
The impact of the COVID-19 pandemic on DKA severity in Black and White pediatric patients
Authors: Patel Shrina , Amador Elyzabeth , Fischell Jonathan M. , Bewley Erin , Jeffries Kaitlin , Newton Paula G. , Fischell Stefanie Zaner
Published: February 2025

Objectives

Diabetic ketoacidosis (DKA) is a complication of uncontrolled diabetes mellitus, with a known increase in severity and incidence during the COVID-19 pandemic. Our institution also observed a rise in pediatric DKA cases in our largely underserved patient population. We hypothesized that the impact would be more pronounced in Black patients due to prepandemic healthcare inequities.

Methods

To investigate this, we confirmed the increased number of severe DKA cases in our pediatric patients during the pandemic and then stratified data to compare laboratory values between Black and White patients. We analyzed patients with a DKA diagnosis admitted to our institution’s pediatric intensive care unit (PICU) prior to the pandemic (March 2016 to December 2017) and during its peak (March 2020 to December 2021).

Results and Conclusions

Our data demonstrated more cases of severe DKA overall during 2020–2021 and when compared to prepandemic years, a statistically significant increase in severity for Black, but not White patients.
The reference ranges for fetal ductus venosus flow velocities and calculated waveform indices and their predictive values for right heart diseases
Authors: Wu Jian , Ruan Yanping , Gao Xinru , Wang Hairui , Guan Yuxuan , Hao Xiaoyan , Han Jiancheng , Gu Xiaoyan , He Yihua
Published: February 2025

Objectives

This study endeavors to establish comprehensive normal reference ranges and Z score formulas for ductus venosus (DV) flow velocity parameters and calculated waveform indices across different gestational ages in low-risk fetuses. Furthermore, we aim to validate the predictive capabilities of these Z score calculation formulas in fetuses with diverse right heart diseases.

Methods

8,953 singleton low-risk fetuses and 70 fetuses diagnosed with different types of right heart diseases were retrospectively enrolled. The DV blood flow velocities during the cardiac cycle (ventricular systolic wave velocity [S], ventricular diastolic wave velocity [D], atrial contraction wave velocity [A], and time-averaged maximum velocity [Tamx]) and calculated waveform indices (preload index [PLI], peak velocity index [PVI], pulsatility index [PI], S/A, and S/D) were obtained. Ninety low-risk fetuses were randomly selected as the control group to verify the predictive value of the Z score model for fetuses with different types of right heart diseases.

Results

As gestational age increased (16–39 weeks), the mean values of S, D, A, and Tamx progressively increased; conversely, the mean values of PLI, PVI, PI, and S/A decreased, respectively, and the median value of S/D remained stable. The Z score-transformed A, PLI, PVI, PI, and S/A could serve as predictors of overall right heart diseases. Different DV Doppler parameter Z scores exhibited varying predictive values for different subtypes of right heart diseases.

Conclusions

Normal reference ranges and corresponding Z score calculation formulas for DV hemodynamic parameters were established, which have demonstrated significant diagnostic values in identifying right heart diseases.