bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Health Education Among Nurses in Promoting Medication Adherence: Strategies and Outcomes
Authors: Alanazi Awatif Mukhlef , Al guhani Maged Fahad , Althobity Sultan Abdullah , Alharthi Majed Dhafer , Alotaibi Sami Dawi , Al Ghamdi Fouad Abdullah
Published: January 2025

The involvement of nurses in patient care has been shown to enhance patients' ability to self-manage their medications and promote discussions about adherence issues. Medication non-adherence continues to be a pervasive and persistent problem, highlighting the need for effective communication between physicians, nurses, and patients. Despite its critical importance, conversations about non-adherence are often inadequately addressed by both physicians and patients, for reasons that are not fully understood. As a result, nurses frequently take on the responsibility of bridging this communication gap by providing reassurance and motivating patients to follow their prescribed medication regimens. Given that medication preparation and administration are fundamental aspects of nursing practice and considering the crucial role nurses play in ensuring medication safety, their involvement in practical procedures within hospitals and community health centers is essential. This includes the identification and reporting of medication errors. However, the knowledge level among practicing nurses has been found to be inadequate. Current literature suggests that nurses often lack sufficient education, which impedes their ability to develop effective communication skills, particularly regarding medication adherence. It is insufficient for nurses to acquire these skills solely upon entering practice; they would be more confident with enhanced healthcare knowledge and training integrated into their educational programs. Nurses bear significant pharmacotherapeutic responsibilities, influenced by both the healthcare setting and their educational training. Strategies to improve patient adherence to treatment and to identify adverse drug reactions have been well-documented in the literature. It is essential for nurses to develop more innovative strategies to ensure consistent follow-ups and to make educational activities more engaging and beneficial for patients. The objective of this review is to assess the current literature on the role of health education by nurses in promoting medication adherence.
Strategies for Managing Medication Compliance in Complex Chronic Conditions
Authors: Albishi Bandari Saad , Baraja Mervat Abdullah , Amashah Adel Eabdalrahim , Alzahrani Bandar Mohammed , Alshaeri Afnan Mohammad
Published: January 2025

Medication adherence is a crucial determinant of therapeutic success, particularly in managing chronic conditions that require long-term, often complex, treatment regimens. Despite its importance, adherence remains a significant challenge globally, with non-compliance rates ranging from 30% to 50%, leading to disease progression and increased healthcare costs. Addressing these challenges necessitates multifaceted approaches that integrate behavioral, technological, and collaborative strategies. Behavioral interventions, including motivational interviewing and cognitive-behavioral therapy, focus on modifying patient attitudes and behaviors toward medication. These approaches align treatment goals with patient values, enhancing engagement and adherence. Simultaneously, technological innovations such as mobile health applications, smart pill dispensers, and biosensors provide real-time monitoring and support, empowering patients while enabling timely healthcare provider interventions. Collaborative care models and multidisciplinary approaches play a critical role by leveraging the expertise of various healthcare professionals, including physicians, pharmacists, and behavioral health specialists. These frameworks ensure a holistic focus on patient needs, addressing barriers such as regimen complexity, psychosocial challenges, and financial constraints. Furthermore, the integration of community health workers and the use of shared electronic health records facilitate coordinated care and better outcomes. Patient education remains a cornerstone across all strategies, ensuring individuals understand their conditions and treatment regimens. This foundational element enhances self-management and long-term adherence. Technological advancements, coupled with data-driven analytics, augment these efforts by providing actionable insights into patient behaviors and enabling proactive interventions. Through a combination of patient-centered care, innovative technologies, and collaborative efforts, these strategies aim to overcome the multifactorial barriers to medication adherence. Such integrative approaches are essential to improving outcomes, reducing healthcare costs, and enhancing the quality of life for individuals managing chronic conditions. These advancements pave the way for sustainable and effective solutions to one of healthcare’s most persistent challenges.
Impact of Adherence to Treatment with Inhaled Corticosteroids/Long-Acting β-Agonists on Asthma Outcomes: A Systematic Review
Authors: Almalki Razan Ali , Alzahrani Anas Hassan
Published: January 2025

Background: The management of asthma primarily involves a continuous regimen of inhaled corticosteroids (ICS) combined with long-acting beta-agonists (LABA). Non-adherence can lead to poorly controlled asthma, resulting in more frequent exacerbations, increased emergency room visits, and higher hospitalization rates. By systematically reviewing existing studies on adherence, this review aims to aggregate and analyze data to elucidate how variations in adherence levels to ICS/LABA impact asthma outcomes. Methods: A comprehensive search was conducted across multiple electronic databases, including PubMed, Scopus, ScienceDirect, Cochrane Library, and Web of Science. Peer-reviewed studies on asthma treatments involving ICS and/or LABAs focusing on assessing how adherence to these medications impact several key outcomes for patients. Screening, data extraction, and quality assessment were performed independently by two reviewers, with discrepancies resolved through discussion. Results: Findings from the included studies on asthma medication adherence reveal that higher adherence rates are linked to improved asthma management and reduced exacerbations. The adherence rates varied widely, with some studies reporting as high as 85% and others as low as 6%. Better adherence generally led to improved quality of life and fewer asthma-related exacerbations. Healthcare utilization costs also varied, with a range from $521 to $836. Barriers to adherence included fear of side effects and forgetfulness. Interventions such as enhanced education for both patients and providers, along with better medication management, particularly with combination inhalers, were suggested to improve adherence. Overall, consistent adherence to asthma medications is crucial for effective symptom control and reducing exacerbation rates. Conclusion: Future research should focus on developing and testing interventions specifically designed to address adherence barriers, additionally, exploring the impact of different inhaler combinations on long-term adherence and asthma outcomes could provide further insights.
Thực trạng quản lý hoạt động ứng dụng công nghệ thông tin trong dạy học ở các trung học cơ sở thành phố Bạc Liêu, tỉnh Bạc Liêu
Authors: Trần Kim Thi , Đào Hoàng Nam
Published: January 2025

Việc ứng dụng công nghệ thông tin trong dạy học nói chung và trong dạy học cấp trung học cơ sở nói riêng là một phần quan trọng trong quá trình đổi mới giáo dục theo hướng hiện đại hóa và hội nhập quốc tế. Để góp phần thực hiện đổi mới giáo dục cũng như nâng cao hiệu quả hoạt động ứng dụng công nghệ thông tin ở các trường trung học cơ sở thành phố Bạc Liêu, chúng tôi đã sử dụng phối hợp các phương pháp nghiên cứu như điều tra bảng hỏi, quan sát và phỏng vấn trao đổi với 105 khách thể gồm cán bộ quản lý và giáo viên ở 6 trường trung học cơ sở thành phố Bạc Liêu. Thông qua kết quả khảo sát chúng tôiphân tích, đánh giá thực trạng quản lý hoạt động ứng dụng công nghệ thông tin ở các trường trung học cơ sở thành phố Bạc Liêu, bao gồm công tác lập kế hoạch, tổ chức thực hiện, chỉ đạo và kiểm tra đánh giá. Kết quả nghiên cứu là căn cứ giúp các nhà quản lý giáo dục địa phương đề xuất biện pháp quản lý hoạt động ứng dụng công nghệ thông tin trong dạy học tại các trường trung học cơ sở thành phố Bạc Liêu, tỉnh Bạc Liêu trong thời gian tới.
Biện pháp quản lý hoạt động dạy học môn Tiếng Việt của các trường tiểu học ở huyện Mỹ Tú, tỉnh Sóc Trăng theo định hướng phát triển năng lực
Authors: Hồ Văn Thống , Nguyễn Văn Dương
Published: January 2025

Hoạt động dạy học môn Tiếng Việt theo định hướng phát triển năng lực đóng vai trò quan trọng trong việc hình thành phẩm chất và năng lực ngôn ngữ cho học sinh tiểu học, đáp ứng yêu cầu đổi mới giáo dục theo Chương trình Giáo dục phổ thông 2018. Bài báo phân tích thực trạng quản lý hoạt động này tại các trường tiểu học ở huyện Mỹ Tú, tỉnh Sóc Trăng. Các hạn chế chính bao gồm: nhận thức chưa đồng bộ của cán bộ quản lý và giáo viên; kế hoạch quản lý chưa toàn diện và thiếu thường xuyên; phương pháp dạy học và kiểm tra, đánh giá chưa đổi mới hiệu quả; công tác bồi dưỡng giáo viên chưa được chú trọng; cơ sở vật chất và tài liệu hỗ trợ còn thiếu; sự phối hợp giữa nhà trường và gia đình chưa hiệu quả.Bài báo đề xuất các biện pháp quản lý như: bồi dưỡng nâng cao nhận thức; cải tiến xây dựng kế hoạch dạy học; đổi mới tổ chức và phương pháp giảng dạy; tăng cường chỉ đạo và giám sát hoạt động dạy học; đẩy mạnh kiểm tra, đánh giá một cách khách quan. Những biện pháp này hướng đến nâng cao chất lượng dạy học môn Tiếng Việt tại các trường tiểu học, góp phần thực hiện hiệu quả Chương trình Giáo dục phổ thông 2018 và phát triển năng lực ngôn ngữ toàn diện cho học sinh.
Myclobutanil poisoning: A case report emphasizing the importance of prompt diagnosis and appropriate management
Authors:   Department of Pharmacy Practice, Deccan School of Pharmacy, Hyderabad, Telangana, India., Shreen Sara
Published: January 2025

Myclobutanil is a fungicide commonly used in agriculture and horticulture. While it is generally considered safe, ingestion of myclobutanil can result in severe toxicity. This case report presents the clinical features, diagnosis, and management of a 45-year-old male with myclobutanil poisoning.
Clinical automation in the era of robotics: Biomedical robots for hospital disinfection
Authors:   Computer Science Department, Federal University of Lavras, Brazil., Matthew Ugochukwu Okwudili
Published: January 2025

Electromagnetic spectrum infrastructures and 5G biomedical robots are design to work in line with the national healthcare policy to advance the society well-being and improve human life expectancy as they are adopted to fight against hospital acquired infection.
Influence of the Bladder and Rectum Volume Changes on their Received Dose During the Prostate Hypofractionated Radiotherapy
Authors: Iamandi A. A. , Smorodina M. N.
Published: January 2025

Purpose: Strict control of patient anatomy during each radiation fraction and aims to determine the magnitude of interfractional changes in pelvic volume and displacement during the prostate hypofractionated radiotherapy to assess potential dosimetric effects on critical organs.
Material and methods: 61 patients with I II stage prostate cancer at very low, low or intermediate risk of progression with a prostate volume <80 cm. for transrectal ultrasound or CT/MRI with contrast was first radiated with a dose of 7.5 Gy per fraction every other day. The treatment consisted of 5 fractions. A comparative analysis of bladder and rectal filling was performed between topometric CT and cone beam CT (CBCT) obtained before each fraction.
Results: The dependence of the doses received by the bladder and rectum on the deviations in their filling was determined. It was shown that, despite preradiation preparation, it is not possible to predict a critical deviation threshold-one at which the dose received by a critical organ will not significantly differ from the planned dose.
Conclusion: The need for strict control of hollow organ filling during prostate irradiation has been demonstrated.
Radiation Safety of Patients in Diagnostic Radiology in the Russian Federation: Current Status, Problems and Solutions
Authors: Vodovatov A. V. , Romanovich I. K. , Alekhnovich A. V. , Biblin A. M. , Akhmatdinov R. R. , Druzhinina P. S. , Kapyrina Yu. N. , Ryzhov S. A.
Published: January 2025

The paper presents an analysis of the structure and collective dose of diagnostic Xray examinations in the Russian Federation in 2018-2022 to assess the trends in the development of Russian X-ray diagnostics. The study was performed based on the results of the analysis of federal state statistical observation forms (radiationhygienic passports and form №3-DOZ for the 2018-2022 period). The results of the analysis indicated that the considered time interval can be divided into several periods: pre-pandemic (2018-2019), pandemic (2020-2021) and post-pandemic (2022); each of which had its own features of the structure of X-ray diagnostics and, consequently, the collective dose from medical exposure. During 2018-2022 period collective dose from medical exposure has increased by a factor of 1,5: from 85000 manSv to 134000 manSv, mainly due to computed tomography. The contribution of computed tomography to the collective dose has increased from 54 % in 2018 to 74 % in 2022. The results of analysis of the distributions of average effective doses for the most common Xray procedures indicated that, in contrast to the above-mentioned indicators, the average doses did not change significantly over the period considered. The study allowed identifying regions of the Russian Federation systematically presenting incorrect (underestimated) average effective doses from X-ray examinations. Based on the results of analysis, proposals were developed to improve the system of radiation protection of patients from medical exposure. Successful practical implementation of these proposals will allow obtaining reliable data on patient and staff doses in the Russian Federation and avoiding excessive increase in doses from medical exposure.
Formation and Dosimetry of Proton Beams for Flash Therapy Study
Authors: Akulinichev S. V. , Kokontcev D. A. , Merzlikin G. V. , Yakovlev I. A.
Published: January 2025

Purpose: To develop methods for tuning and dosimetry of proton beams in the widest possible range of proton current, including flash therapy modes with extremely high dose rates. Studies of flash therapy patterns, which have become much more active in recent years, have increased interest in the methods of forming therapeutic proton beams, including the method of passive proton scattering used in this work.
Material and methods: The characteristics of the highcurrent linear proton accelerator of the INR RAS make it a unique facility and allow work with proton beams of record intensity. The therapeutic beam formation system is developed based on the principle of double passive proton scattering, which allows instantaneous irradiation of biological objects of significant size with a uniform dose regardless of the beam intensity. The primary adjustment of the formation system is performed using a standard MP-3 water phantom (PTW, Germany) at low proton currents, i.e. in the conventional irradiation mode. The proposed method of setting up the beam formation system allows combining the secondary shaped scatterer with the beam center and finding the optimal angle of the energy modulator, thereby optimizing the depth dose distribution. The used methods of dosimetry and beam control with film detectors and a Cherenkov monitor are also applicable at high proton currents, which allows setting up the beam formation system and irradiating biological objects in flash therapy modes.
Results and conclusion: The work developed methods for the formation and dosimetry of proton beams applicable in the widest possible range of proton beam intensities, up to proton current values of about 10 mA. The main practical result of the work is the implemented irradiation of biological targets weighing up to 100 g with protons in a single pulse with a record average dose rate for protons per fraction of about 106Gy/s. For this purpose, original methods for setting up the beam formation system elements and Cherenkov beam monitors were used.
Towards the Intelligent Technical Systems with Artificial Consciousness
Authors: Rogatkin D. A.
Published: January 2025

Analysis of modern trends in the development of artificial neural network technologies, deep machine learning, etc. shows that in the near future, an assault on one of the central and unsolved problems of scientific natural science will inevitably begin all over the world the problem of creating a fundamental theory of consciousness and applying it in practice to create technical systems (TS) with elements of self-awareness, in the image and likeness of humans and animals. If until recently, philosophers and doctors paid attention to the problems of consciousness, then in the last two decades, in connection with the mass introduction of "intelligent" information and robotic technologies into practice, including medical technologies, serious engineering publications began to appear on the issues of the existence of consciousness in living nature and the tasks of its reproduction in TS. This review collects and analyzes the main data known in biology, medicine and natural science in general on the phenomenon of consciousness. Arguments are given in favor of the possibility of an engineering and technical formulation of the problem of creating intelligent TS that are separately aware of themselves and the world around them. A number of considerations are also put forward as to what basic principles may underlie such engineering and technical hardware and software solutions. A simple working engineering and technical definition of consciousness is proposed as a high-level control mode of a multisensory mobile system designed to act autonomously in a changing external environment, guided by personal goals and meanings. Based on well-known examples from wildlife, the regularity of the evolutionary emergence of consciousness in animals is substantiated both in terms of phylogenesis and early ontogenesis. The indispensable role of the endocrine system in control in the animal world is shown, as well as a concept for its implementation by technical means in conjunction with neural networks is proposed.
Landscape Ecological Risk Assessment in the Southwestern Fringe of Guwahati City, India
Authors: Sarmah Rakesh Kumar , Sarma Santanu
Published: January 2025

Rapid urbanization targets in developing countries often underestimate the ecological balance between nature and humanity. Urban fringe or peri-urban landscapes need critical attention due to their increased vulnerability as areas for potential investments and rural-urban jurisdiction dichotomy. Through this study, an attempt has been made to assess the spatiotemporal landscape ecological risk associated with the south western fringe areas of Guwahati city using remote sensing and GIS technology. The Landsat satellite imagery from 1991 and 2011 is utilized to analyse the land use land cover (LULC) dynamics using random tree classifier technique. For accuracy enhancement, Normalized Difference Vegetation Index (NDVI) and the Normalized Difference Building index (NDBI) are incorporated. Standard formulae are used to determine the landscape ecological risk in a grid approach, and Bayesian kriging interpolation is adopted for the representation of the results. During this period the built-up area increased from 34.95 km2 to 74.72 km2 . The increase in built-up areas is more prominent towards the north, adjacent to the Guwahati airport. 17.90% of cropland and 12.60% of sparse vegetation mainly contributed to this increment. The cropland area decreased from 121.87 km2 to 104.11 km2 . The change in sparse vegetation is more compared to dense vegetation. The sparse vegetation patches are converted mainly into built-up, dense vegetation, and cropland. Sandbars, swamp/waterlogging, and waterbodies show a decrease in this period. The landscape ecological risk results show the concentration of high-risk areas in the central valley portion of the study area for 1991 covering 27.26%, which gradually shifted towards the south in 2011 with 15.11% area coverage. The subhigh-risk area also shows a significant increase in area coverage from 22.38% to 33.33%. The medium and sub-low-risk areas show a small increment from 21.56% to 23.92% and 18.41% to 19.13% respectively. The low-risk areas show a decrement from 10.39% to 8.52% during this time frame. The study will provide a sustainable framework integrating ecological values in urban planning and policy-making.
Measurement of Uranium Concentrations in the Soil Samples of Nineveh Province, Iraq Using CR-39 Detector
Authors: Malik H. Kheder  , Hanaa N. Azeez
Published: January 2025

The physiological influence of radiation, which may induce cancer, makes the radioactive field vital to human health. Radon, which is hazardous to both humans and the environment, is deposited in soil via uranium decay. Extended exposure to elevated levels of alpha radiation, primarily radon, causes lung cancer. Thus, research is necessary to observe how the levels of human exposure vary. In evaluating natural exposure radiation, it is essential to control the quantity of radionuclides in the soil by determining the radioactivity level from these sources. Twenty samples of soil from different places in the Nineveh province in northern Iraq were analyzed for uranium content by the CR-39 nuclear track detector. These samples had radon concentrations ranging from 27.221 to 59.407 Bq.m-3, and the mean is 38.917 Bq.m-3. This mean value is below the level of reference limits 100 Bq.m-3 of the World Health Organization (WHO). Uranium levels ranged values from 0.129 to 0.281 ppm, with a mean of 0.182 ppm. Findings demonstrate that the natural radiations in the region are within the permissible range, as shown when comparing the results to global averages, the uranium concentration levels fell below the average of global value 2.8 ppm, and below the acceptable limit of 11.7 ppm.
Adaptación cultural de una terapia de estimulación cognitiva
Authors: Medel Nancy , Solís Patricia , Mintz Inés , Villella Ivana , Fisher Emily , Kochen Silvia , Spector Aimee
Published: January 2025

Introducción: La Terapia de Estimulación Cognitiva (TEC) se originó en el Reino Unido. Se trata de un programa de estimulación que ha demostrado en un estudio multicéntrico, leatorizado y de diseño controlado beneficios en la cognición y la calidad de vida de los pacientes con demencia. La TEC fue adaptada e implementada en más de 30 países. Consiste en 14 sesiones grupales, semanales para 6 a 8 participantes. Material y Método: En este trabajo presentamos la adaptación cultural de la Terapia de Estimulación Cognitiva siguiendo las directrices para la adaptación de la terapia de estimulación cognitiva a otras culturas traducidas al español para ser utilizadas en nuestro país. Utilizamos el método de adaptación, denominado “Modelo Formativo para adaptar Psicoterapia” (MFP), “de abajo hacia arriba”, que está fundado en la consulta a la comunidad. Iniciamos el proceso con la traducción del manual, posteriormente lo adaptamos con la información obtenida en consultas a pacientes, familiares, cuidadores y profesionales de la salud. Finalmente probamos la viabilidad y la adecuación cultural de la Terapia al español. Resultados: Se necesitaron algunas modificaciones, especialmente relacionadas con cuestiones lingüísticas, en 10 de las 14 sesiones. Pudimos realizar una adaptación culturalmente apropiada de esta Terapia para Argentina. El manual de sistematización y adaptación cultural está listo para ser utilizado para su implementación y validación en un mayor número de grupos y en diferentes lugares del país.
Estudio prospectivo de manifestaciones neuropsiquiátricas y cognitivas post accidente cerebrovascular
Authors: Berrios Waleska , Deschle Florencia , Marroquín Verónica , Ziegler Gabriela , Fariña Sofía , Pacha María Sol , Cervino Cecilia Verónica , Saglio María Laura , Albornoz José Ignacio , Povedano Guillermo
Published: January 2025

Introducción: El accidente cerebrovascular es un factor de riesgo para el trastorno neurocognitivo. Se ha reportado la presencia de trastorno neurocognitivo post accidente cerebrovascular en el 20 al 80 % de los casos, según diferentes series. Asimismo, se reportan síntomas neuropsiquiátricos luego de ese evento, siendo lo más frecuente la depresión. El objetivo de este estudio fue determinar la prevalencia de trastorno neurocognitivo, depresión y otros síntomas neuropsiquiátricos en sujetos con un primer accidente cerebrovascular isquémico. Métodos: Se evaluaron sujetos adultos con un primer accidente cerebrovascular isquémico, a los 3 y 12 meses del evento, con una evaluación neuropsicológica estándar, Inventario de Depresión de Beck-II e Inventario Neuropsiquiátrico de Cummings. Se clasificaron los casos como desempeño cognitivo normal, trastorno neurocognitivo menor o mayor según criterios del DSM 5. Resultados: Se incluyeron 36 pacientes con una media de edad de 60.97 ± 16.98 años. Se registró trastorno neurocognitivo (mayor y menor) en 63.8 % de los casos a los 3 meses y 66.6 % de los casos al año, síntomas conductuales según Inventario Neuropsiquiátrico en 69.4 % de los casos a los 3 meses y 50 % de los casos al año, y síntomas depresivos según Inventario de Depresión de Beck-II en 16.6 % de los casos a los 3 meses y en 22.2 % de los casos al año. La hipertensión arterial fue el factor de riesgo modificable más frecuente y se correlacionó con la presencia de trastorno neurocognitivo. Discusión: La detección de trastorno neurocognitivo y síntomas neuropsiquiátricos post accidente cerebrovascular es necesaria en base a la elevada prevalencia reportada, permitiendo así un correcto abordaje y rehabilitación integral.
Análisis de calidad y otras conductas relacionadas con el sueño durante los últimos días de la pandemia por COVID-19 en Argentina
Authors: Valiensi Stella Maris , Folgueira Agustín L. , Enriz Noelia M. , Garay Arturo , Giardino Daniela L.
Published: January 2025

Objetivo: evaluar la calidad, hábitos y algunos trastornos del sueño días previos a la declaración del fin de la pandemia por COVID-19. Método: estudio observacional de corte transversal. Encuesta en línea distribuida a través de una plataforma web desde el 1 de marzo al 15 de abril 2023. El análisis consideró: información demográfica, calidad del sueño y algunos cambios de hábitos/conductas. Resultados: se evaluaron N=2081 respuestas. La edad media fue de 37 ± 12 (16-86 años). El 56,5 % de las respuestas fueron del Área Metropolitana de Buenos Aires y el 70,7 % eran mujeres. El 68,3 % presentaba mala calidad de sueño. El 31,8 % dormía con mascotas. El 44,2% refirió trastornos en la conciliación del sueño y el 34,9% que dormía menos de seis horas. El 25,5 %  que la eficiencia de su sueño era inferior al 75%. Refirieron alteraciones en el mantenimiento del sueño el 25,3 %; ronquidos el 15 %; pesadillas el 16.4 %; bruxismo el 20.4 % y síndrome de piernas inquietas el 14.8 %. La mala calidad del sueño se asoció con el sexo femenino (p=0,00), con los que residían en el Área Metropolitana (p=0,01) y con los que dormían con mascotas (p=0,00). El sexo femenino presentó mayor prevalencia de síntomas del síndrome de piernas inquietas (p=0,00). Conclusiones: el análisis identificó que más de la mitad de la población refirió mala calidad del sueño principalmente mujeres, residentes en el área metropolitana y en quienes dormían con mascotas.
Conocimientos, actitudes y prácticas sobre diagnóstico y manejo del delirium en el Hospital Cayetano Heredia
Authors: Díaz-Vargas Grethel , Quiñones-Condezo Abigail , Acurio-Ortiz Karlos , Pacheco- Barrios Niels , Bertorini Tulio , Arévalo-Flores Martin , Vega-Dienstmaier Johann M. , Orellano Carlos
Published: January 2025

Introducción: El delirium es un síndrome prevalente en la práctica clínica. El objetivo del estudio fue identificar los conocimientos, actitudes y prácticas sobre delirium en el personal médico en un hospital de tercer nivel, así como evaluar la validez del instrumento creado para este fin. Métodos: Se realizó un estudio transversal de 3 fases: 1) validación de contenido, 2) aplicación del instrumento y 3) validación del constructo. Resultados: Tras una validación de contenido satisfactoria, se aplicó el instrumento a 148 participantes. Respecto a los conocimientos sobre delirium, hubo una media de aciertos de 57,8 % (IC95 % 52,5-63,1) sin diferencia significativa entre médicos asistentes, residentes y estudiantes de último año de medicina. Un 25 % (n=37) refirió usar el Método para la Evaluación de la Confusión, un 31,1 % (n=46) refirió sentirse confiado en el uso de antipsicóticos en el manejo del delirium, y un 86,5 % (n=128) refirió usar al menos una medida no farmacológica. Conclusiones: Se evidenciaron deficiencias en conocimientos y manejo del delirium en el personal médico. El instrumento tuvo una óptima validación de  contenido, pero insatisfactoria validación de constructo. Se enfatiza la importancia de hacer un análisis psicométrico con individuos, previo a la aplicación del instrumento.
Rodolfo Senet: otra mirada sobre la misoginia en el publicismo argentino
Authors: Conti Norberto Aldo
Published: January 2025

Incluye algunas opiniones sobre la obra: ¿Es superior el hombre a la mujer? (1912), Buenos Aires, de Rodolfo Senet (1872-1938).
Quality improvement of the medication system in a long-term care facility: a hybrid effectiveness-implementation study
Authors: Plauska Ana Ludmila Santos , Silva Hágabo Mathyell , Ramos Juliana de Oliveira Gomes , Rezende Cristiane de Paula , Nascimento Mariana Martins Gonzaga do
Published: January 2025

Objective: To describe the implementation of a quality improvement intervention for the medication system of a large not-for-profit long-term care facility (LTCF) and evaluate its effectiveness. Methods: A type 2 effectiveness-implementation hybrid longitudinal study was carried out. We first conducted a diagnosis of the existing medication system, which included the administration of a questionnaire to LTCF staff. Then, an individualized unit-dose dispensing system was implemented and the medication system’s flow was adjusted to the local reality. The effectiveness of the quality improvement intervention was assessed by comparing the following pre- and post-implementation factors: 1) time spent on each step of the medication system; 2) strengths and weaknesses observed. Results: The diagnosis demonstrated multiple points of failure in the medication system. However, the answers to the questionnaire ran counter to what was identified, indicating a lack of knowledge about patient safety. The quality improvement intervention was associated with the following improvements in the medication system: 1) reduction in the number of prescription transcriptions; 2) reduction of medication shortages; and 3) improvement of organization, dynamics, and traceability in distribution, preparation, and administration. An average reduction of 3 hours and 57 minutes in the time spent distributing, preparing, and administering medications was also identified. Conclusions: The quality improvement intervention was effective, increased the providers’ available time, and improved the safety of medication use in the LTCF.
Bioactive Potential of Premna esculanta: A Study on Antioxidant, Antimicrobial and Antidiarrheal Efficacy
Authors: Yousuf Hafijul , Shohag Al Mamun , Miah Md Shawon , Rahman Md Foyzur , Mahmud As-Sazzad
Published: January 2025

Article
Bioactive Potential of Premna esculanta: A Study on Antioxidant, Antimicrobial and Antidiarrheal Efficacy

Hafijul Yousuf, Al Mamun Shohag, Md Shawon Miah, Md Foyzur Rahman and As-Sazzad Mahmud *

Department of Pharmacy, Dhaka International University, Dhaka 1212, Bangladesh
* Correspondence: sazzad.phar@diu.ac; Tel.: +880-1521305611

Received: 20 October 2024; Revised: 9 November 2024; Accepted: 14 November 2024; Published: 10 January 2025

Abstract: Objective: The discovery of the genus Premna and its traditional uses are the result of extensive information gained by living in forest or semi-forest areas and closely observing indigenous populations regarding the therapeutic qualities of plants. This investigation centered on examining the DPPH scavenging, antimicrobial and anti-diarrheal properties of ethanolic leaf extracts. This study aimed to investigate the bioactive components and antibacterial properties of ethanolic leaf extracts and their fractions. Methods: In vitro antioxidant was evaluated by DPPH scavenging assay and the disc diffusion method evaluated antimicrobial efficacy. In vivo screening for antidiarrheal was conducted, the latent period of defecation in castor oil-induced diarrhea in mice assessed antidiarrheal effects. Results: The extract showed an ability to scavenge DPPH with IC50 values of 0.931 µg/mL for Premna esculanta extract and IC50 0.902 µg/mL for ascorbic acid standard. The extract demonstrated significant antimicrobial activity, with inhibition zones ranging from 12–19 mm against various microbial strains, notably Shigella boydii, Shigella dysenteriae, Pseudomonas aeruginosa, Escherichia coli, Sarcina lutea, Bacillus subtilis, and Candida albicans, at concentrations of 250 and 500 µg/disc. In anti-diarrheal test, Loperamide (3 mg/kg) reduced total feces and defecation by 56.62% with concentrations of 500 mg/kg. Significant changes were observed in anti-diarrheal studies. Conclusion: Premna esculanta leaf extract demonstrated significant antimicrobial, and antidiarrheal activities.
Feasibility of recycling marble waste powder as fine aggregate in self-compacting sand concrete
Authors: Guendouz Mohamed , Boukhelkhal Djamila , Benatallah Loubna , Hamraoui Somia , Hadjadj Moussa
Published: January 2025

Building materials generate about half of solid waste worldwide, with an environmental impact at every step of its production process, i.e., extraction of raw materials, processing, manufacturing, transportation, construction, and disposal at the end of a building’s useful life. Among these materials, we distinguish the marble powder waste (MW). This work aims to study the possibility of recycling MW, especially those from the cutting and polishing process of marble stone discharged in nature. After collecting, these wastes were crushed, extruded in the form of grains, and used in the mass of self-compacting sand concrete (SCSC) as a partial replacement of natural sand volume with different percentages (10, 20, 30, 40, and 50%). The obtained results show a decrease in the fluidity and an increase in the density and occluded air of SCSC with increasing MW content. However, the compressive and flexural strengths of SCSC are improved by about 24% and 28% for a 10% substitution ratio of natural sand with MW and maintained comparable to CSCSC for up to 50% MW. The capillary water absorption, shrinkage, and thermal conductivity of all MW-based SCSCs are greater than those of the control SCSC. However, up to 40% of MW content, all SCSC mixes are classified as acceptable for structural application with water absorption and shrinkage less than 10% and 1000 m/m, respectively. This study also ensures that reusing marble wastes in SCSC gives a positive approach to reduce the cost of materials and solve some environmental problems.
Integrated crashworthiness analysis of vehicle chassis and battery modules using Abaqus
Authors: Benbellil Billal
Published: January 2025

This study explores vehicle crashworthiness through numerical simulation and analysis using Abaqus/Explicit, a finite element solver specialized in dynamic and nonlinear problems. The research evaluates deformation, stress distribution, and energy absorption in vehicle structures and battery modules under high-speed collision scenarios. Parametric studies were conducted on Tesla Model S chassis and battery shells, analyzing impact velocities from 27.7 m/s to 100 m/s and shell thicknesses of 1 mm and 3 mm. The results revealed significant variations in performance due to material properties, geometry, and impact conditions. The 3 mm battery shell demonstrated superior energy absorption and reduced deformation compared to the 1 mm shell, particularly at higher velocities. Stress analysis identified critical zones on the chassis and battery module, highlighting the need for strategic reinforcements. Thermal evaluations showed increased risks of thermal runaway in thinner shells, emphasizing the importance of robust thermal management systems for electric vehicles (EVs). Key findings include the effectiveness of thicker shells in mitigating stress and damage, the role of optimized crumple zones in enhancing chassis performance, and the necessity of high-strength materials like aluminum 6061-T6 and ASI430 stainless steel. This research provides practical recommendations for designing safer, more reliable EVs, contributing to crashworthiness analysis methodologies and laying the groundwork for future experimental validations.
Evolution of the electron transport parameters in He/H2 and Ne/H2 mixtures
Authors: Mostefaoui Mohamed , Taleb Rachid
Published: January 2025

Understanding all electron swarm parameters as a function of the reduced electric field is critical for fluid modeling of low pressure electrical discharges. The development of accurate models of electrical discharges in gaseous media requires fundamental data such as electron collision cross sections for particle modeling and electron swarm parameters for fluid modeling. This knowledge is essential for fluid models based on the first and second moments of the electron energy distribution function. To achieve this, we use a specially developed BE solver, BOLSIG+, which is more versatile and provides a steady-state solution of the Boltzmann equation for electrons in a uniform electric field. It is based on the classical two-term expansion for quasi-stationary and oscillating fields, taking into account electron-neutral and electron-electron collisions. In this paper we present the evolution of the transport coefficients as a function of the reduced electric field in He/H2 and Ne/H2 mixtures. In particular, we calculate the electron mobility, the characteristic energy and the ionization coefficient for these mixtures and compare the obtained results with experimental measurements by different authors.
Abdominoplastia: benefícios e malefícios em pacientes pós-bariátrica
Authors: Martins Emille Macedo , Oliveira Maria Clara do Carmo de , Simão Ana Lívia Alves , Matos Bianca Xavier , Palhares Tânia Miranda , Machado Barbara Novais Prado , Viza Lorene Alarcão , Elias Pedro Henrique Arenas , Boaventura Tacyla Gabrielle Mendonça , Vargas Aline Bezerra , Pereira Franciely dos Passos , Brito Isadora Pereira , Quirino Carolaine Cristina , Donon Amanda Stefani Fernandes
Published: January 2025

Este artigo visa fornecer uma síntese dos benefícios e malefícios da abdominoplastia em pacientes pós-bariátricos. O problema investigado está relacionado às complicações pós-operatórias, como seromas e infecções, e aos impactos positivos na autoestima e saúde metabólica. O objetivo da pesquisa é delinear as vantagens e desvantagens desse procedimento, considerando a complexidade dos casos e os riscos associados. A metodologia utilizada foi uma revisão integrativa da literatura, que envolveu a análise de estudos publicados entre 2018 e 2024, focando em mulheres entre 20 e 59 anos que realizaram cirurgia bariátrica. Os resultados obtidos indicam que, apesar dos riscos, a abdominoplastia desempenha um papel crucial na melhora da qualidade de vida desses pacientes, contribuindo para a recuperação da autoestima e o bem-estar físico. A análise também sugere a necessidade de um acompanhamento multidisciplinar para minimizar complicações e otimizar os resultados estéticos e funcionais. Conclui-se que, embora seja um procedimento amplamente adotado, a abdominoplastia exige uma avaliação cuidadosa das técnicas e dos riscos envolvidos.
Anestesia locorregional em pediatria: uma avaliação completa dos riscos e benefícios em procedimentos cirúrgicos ambulatoriais
Authors: Santana Alexandre Augusto de Andrade , Rosa Julia Grossi Sampaio , Rocha Juliana Espíndola , Arraes João Felipe Azevedo , Moraes Luiza Ferro Marques , Macêdo Jordana Alves , Avelar Giovana Silveira , Resende Lucas Lisboa , Ataídes João Victor Benevenuto de Queiroz e , Gomes José Victor Lisboa Cardoso , Santana Natan Augusto de Almeida
Published: January 2025

INTRODUÇÃO: A anestesia locorregional, caracterizada pelo bloqueio reversível da condução nervosa em uma região específica do corpo, tem se consolidado como uma modalidade anestésica segura e eficaz em procedimentos cirúrgicos pediátricos ambulatoriais. A utilização de anestésicos locais, seja por via tópica ou por infiltração, proporciona analgesia e anestesia adequadas, minimizando o desconforto perioperatório e facilitando a recuperação pós-operatória. MÉTODO: Trata-se de uma revisão sistemática, na base de dados da PubMed, com os descritores: “local anesthesia” AND “minor surgeries” AND “pediatrics”, nos últimos 10 anos. Foram selecionados 7 artigos científicos, com texto completo e gratuito, sendo excluídos artigos que não se enquadraram nos objetivos do presente estudo. RESULTADOS: A escolha do tipo de anestesia locorregional e do anestésico local a ser utilizado depende de diversos fatores, como a idade da criança, o tipo de procedimento cirúrgico, a experiência do anestesista e as comorbidades associadas. A mistura eutética de anestésicos locais tópicos, por exemplo, tem demonstrado ser uma opção segura e eficaz para procedimentos como a circuncisão neonatal, proporcionando analgesia satisfatória com poucos efeitos adversos. Embora a anestesia locorregional seja considerada um método seguro, é fundamental que o profissional de saúde esteja atento aos potenciais riscos associados ao seu uso, como a toxicidade sistêmica dos anestésicos locais. A toxicidade sistêmica pode manifestar-se por meio de sintomas neurológicos (ex: tonturas, visão turva, convulsões) e cardiovasculares (ex: hipotensão, bradicardia). A dose máxima recomendada, o tempo de ação do anestésico e a presença de vasoconstritores na formulação são fatores que devem ser cuidadosamente considerados para minimizar o risco de complicações. CONCLUSÃO: A anestesia locorregional desempenha um papel fundamental na analgesia e anestesia de procedimentos cirúrgicos pediátricos ambulatoriais, proporcionando benefícios como menor risco de complicações respiratórias, recuperação mais rápida e maior satisfação do paciente e da família. No entanto, a utilização segura dessa técnica exige conhecimento aprofundado da farmacologia dos anestésicos locais, da anatomia regional e da fisiologia do paciente pediátrico. A avaliação cuidadosa dos riscos e benefícios, aliada à monitorização rigorosa dos sinais vitais, é essencial para garantir a segurança e o sucesso do procedimento.
Controle de compactação dos solos por meio do frasco de areia com agregado miúdo da região metropolitana de Manaus-AM
Authors: Maquiné Aldenei de Lima , Damasceno Micael Felipe , Feitoza José Costa
Published: January 2025

Atualmente, utiliza-se o frasco de areia para o controle da compactação dos solos, na maioria das obras de terra no Amazonas, relacionando a massa específica aparente “in situ” com a massa específica aparente seca em função da umidade ótima obtida no laboratório. Trata-se de um ensaio geotécnico com uso de areia lavada, seca e normatizada na faixa granulométrica compreendida entre 0,80 e 0,60 milímetros. A presente pesquisa substitui a areia do frasco padronizado, em norma, pelo agregado miúdo da região metropolitana de Manaus-AM. Os ensaios da granulometria indicam que a areia coletada desta pesquisa é muito uniforme, bem graduada e possui diâmetro máximo característico igual a 1,19 mm. A fração granulométrica predominante classifica o material particulado de Manaus em areia média (56,67%), com a massa específica aparente seca e dos grãos respectivamente iguais a 1,5118 g/cm³ e 2,6042 g/cm³. Executaram-se os ensaios de campo no estacionamento do Instituto Federal do Amazonas (IFAM), Campus Manaus Centro, obtendo-se as massas específicas aparente “in situ” com os frascos de areia padrão igual a 1.727,74 kg/m³ e com agregado miúdo de Manaus o valor de 1.620,13 kg/m³. Avaliou-se satisfatoriamente o Grau de Compactação em função do erro relativo percentual, com vistas à pavimentação no Amazonas.
Estudo comparativo da eficácia na alfabetização em crianças do 1º ano do ensino fundamental por diferentes metodologias
Authors: Rangel Alexandra Fernandes Morais , Jardini Renata Savastano Ribeiro , Canoas-Andrade Rosângela , Neri Waleska Carvalheiro Del
Published: January 2025

As habilidades de leitura e escrita são indispensáveis para a vida dentro e fora das escolas em sociedades democráticas modernas. É um direito humano básico que muitas vezes tem sido negado. Uma alfabetização de qualidade envolve a busca por práticas de ensino que sejam eficientes e que promovam melhores resultados nos níveis de aprendizagem dos estudantes. No Brasil, em 2021, devido à pandemia da Covid-19, o número de crianças entre 6 e 7 anos que não sabiam ler cresceu para 40,8%. Anteriormente à pandemia já era urgente a necessidade de adequar os processos de aprendizagem às reais necessidades das crianças. O objetivo geral desse estudo foi investigar a eficácia de diferentes metodologias de alfabetização, incluindo-se o Método das Boquinhas®, a partir da comparação do desempenho de três grupos de crianças que frequentam o 1º ano do Ensino Fundamental em escolas públicas, nas habilidades verificadas nas Novas Sondagens Boquinhas, em dois tempos. Os resultados do estudo mostraram variação significativa em relação aos fatores grupo e momento, sendo que o grupo experimental que adotou a metodologia Boquinhas® foi o que apresentou resultados mais consistentes.
TOOTH MORPHOTYPES SHED LIGHT ON THE PALEOBIODIVERSITY OF MIDDLE TRIASSIC TERRESTRIAL VERTEBRATE ECOSYSTEMS FROM NE IBERIAN PENINSULA (SOUTHWESTERN EUROPE)
Authors: RICCETTO MARC , MUJAL EUDALD , BOLET ARNAU , DE JAIME-SOGUERO CHABIER , DE ESTEBAN-TRIVIGNO SOLEDAD , FORTUNY JOSEP
Published: January 2025

The Early to Middle Triassic is a key time interval in tetrapod evolution. After the end-Permian biotic crisis, harsh environmental conditions due to global warming and aridity persisted during the Early Triassic. This led to an impoverished biodiversity, especially in equatorial Pangea, until the Middle Triassic, when vertebrate ecosystems re-flourished. The terrestrial European record is characterized by tetrapod communities dominated by temnospondyls and archosauromorphs, followed by a limited presence of lepidosauromorphs, procolophonomorphs and therapsids. Ongoing paleontological sampling at the Anisian Buntsandstein facies of northeastern Iberian Peninsula (southwestern Europe) provides new insights on the vertebrate biodiversity at equatorial paleolatitudes. The Montseny area (Catalan Coastal Ranges) has delivered moderately abundant cranial and postcranial remains in the last decades. Among the known record, dental, mandibular and skull remains are particularly relevant because they provide information on the dietary habits of the concerned taxa. In the present work, eight tooth morphotypes have been identified: two correspond to a capitosaur temnospondyl, one to an archosauromorph, one to an indeterminate diapsid and four to a procolophonid, the latter material referred to a single new taxon, Kapes signus sp. nov. These finds help to fill a gap in the lower Middle Triassic vertebrate biodiversity and distribution in present-day southwestern Europe. Based on dentognathic remains, the oldest Middle Triassic terrestrial tetrapod ecosystems from northeastern Iberia were dominated by capitosaur temnospondyls, followed by much less abundant archosauromorphs, procolophonids and indeterminate diapsids. This contrast with the ichnotaxonomical composition of the study area, denoting paleoenvironmental and/or taphonomic biases in the dental and osteological record.