bluuebunny/crossref_metadata_2025 huggingface dataset:
Immediate anxiety and depression disorders during the initial stage of the 2019 coronavirus disease (Covid-19) epidemic among the general population in Nigeria
Authors: Olarewaju Sunday O , Jegede Oluwatosin S , Ijitade Grace , Akande Ayodeji M
Published: September 2022

Background:

During the initial stage of Covid-19 outbreak in Nigeria, the government took drastic steps in controlling it; this included a total lockdown which left many with fears and worries about their health and household economy. The mental health of people in the society was becoming an issue that cannot be ignored. There was a dearth of information on the impact of Covid-19 on the mental health of the general population.

Objectives:

This study was therefore conducted to explore the prevalence of immediate anxiety and depression disorders and to identify associated factors during the initial stage of Covid-19 outbreak in Nigeria.

Materials and Methods:

The study was conducted in 2020 and was cross-sectional analytical in design. The study population included Nigerians above the age of 18 years. A total of 305 people participated in the study. Data were collected using a structured electronic questionnaire and analyzed using IBM SPSS version 25. Based on the Hospital Anxiety and Depression Scale (HADS), respondents were categorized into normal, having borderline, or having psychological disorders (anxiety or depression).

Results:

The median age of respondents was 30 years (interquartile range 23, 41.5). Three hundred and four respondents were aware of Covid-19. One hundred and twenty-five (41.0%) were assessed to be normal during the initial stage of Covid-19 in Nigeria, 44 (14.4%) had borderline psychological disorder, and 136 (44.6%) had either anxiety or depression. Respondents with occupation classified as others were found to be 52.1% times less likely to have anxiety or depression disorders when compared with civil servants (P = 0.045; 95% confidence interval = 0.23 - 0.99).

Conclusion:

Our study shows that anxiety and depression were widespread during the initial stage of Covid-19 outbreak. Mental health services would be essential in taking care of the psychological needs of Nigerians, especially those who have experienced and survived the scourge of the pandemic.
Improving access to diabetes care in Nigeria – The GIFSHIP opening
Authors: Nwatu Chidimma B
Published: September 2022

Diabetes mellitus, has continued on a relentless upward trajectory globally, with profound socio-economic consequences. Not surprisingly, the International Diabetes Federation in collaboration with the World Health Organization and the United Nations; in commemoration of the World Diabetes Day 2021, aptly chose the theme – ‘Access to Diabetes Care - If Not Now, When?’ for the year 2021 (the centenary anniversary of insulin discovery), till 2023; to underscore the difference which having access to diabetes care can make, in relation to diabetes management. The Group, Individual and Family Social Health Insurance Program (GIFSHIP) is a non-formal sector insurance package for individuals; groups; and family units in Nigeria, recently introduced by the federal government, to improve universal health coverage.

The inherent positive contributions of the GIFSHIP, towards improving access to diabetes care in Nigeria was reviewed.

MEDLINE, Omni and Google Scholar searches were conducted using keywords - access to diabetes care, barriers to diabetes care, GIFSHIP, and Nigeria. Relevant studies were extracted and reviewed. Authors summarized health care access, narrowing down to diabetes care access. The opportunity for improved access to diabetes care, which the GIFSHIP presents was highlighted. The role of the Diabetes Association of Nigeria (DAN) in advancing the uptake of, and utilization of the GIFSHIP package for their members, was explored.

The GIFSHIP showed great promise for improving access to diabetes care in Nigeria, while the DAN was projected as an effective channel for dissemination and uptake of the GIFSHIP among individuals with diabetes.
Fluid aspirates of ameloblastoma
Authors: Nwoga Mark C
Published: September 2022

Background:

Ameloblastoma is a benign cystic odontogenic tumor common in Nigeria. The cystic cavities frequently contain tumor fluids, which may be obtained by needle aspiration. The tumor fluids help in the clinical differential diagnosis. The types, prevalence, and relevance of ameloblastoma fluid aspirates have been mostly unreported.

Objectives:

The aim of this study was to identify the types and prevalence of fluid aspirates of ameloblastoma and evaluate its prognostic relevance.

Materials and Methods:

This was a 7-year retrospective study of consecutive patients with ameloblastoma at a tertiary hospital in Enugu, Nigeria. The tumor fluids obtained by needle aspiration are categorized based on visual appearance. The data retrieved from case files, biopsy forms, histopathologic reports, and other records in the departmental archives were analyzed with IBM SPSS Statistics, version 24.0.

Results:

Tumor fluid aspirate yield was positive in 80.4% ((n=74) of patients with ameloblastoma. There were aspirates from 82.4% (n=61) cases of primary ameloblastoma and 17.6% (n=13) cases of recurrent ameloblastoma. The aspirates obtained were dark-brown 41.9%, straw-colored 37.8%, serosanguinous 10.8%, and purulent 9.5%. The type of aspirate was influenced by the primary or recurrent status of ameloblastoma (P = 0.04). Straw-colored aspirate was obtained from 92.9% of primary ameloblastoma and in 73.1% of patients <20 years of age. Recurrent ameloblastoma typically yielded dark-brown aspirates in 76.9% of recurrences.

Conclusion:

The association of some tumor fluids with primary and recurrent ameloblastoma could improve the understanding of the recurrence potential of the disease and influence treatment planning.
Perception of ocular complications among patients with diabetes mellitus attending tertiary hospitals in Enugu, Nigeria
Authors: Asimadu Ifeoma N , Okeke Suhanyah , Kizor-Akaraiwe Nkiru N , Mbadiwe Nkeiruka C , Mbakigwe Chidi F
Published: September 2022

Background:

Diabetes mellitus can lead to sight and life-threatening complications. It affects people in both developed and developing countries. Many diabetics present to the eye clinics with undetected advanced eye complications.

Aim:

The study aimed at evaluating the perception of the ocular complications of diabetes and how it influences the attitude and practice of the diabetics attending the eye clinics.

Materials and Methods:

A cross-sectional study was conducted in two tertiary hospitals in Enugu over a 3-month period. An interviewer-administered questionnaire was used to assess their perception, and hence their attitude and practice toward diabetic eye complications after obtaining their informed consents.

Results:

A total of 884 diabetics participated. There were 337 (38.1%) males and 547 (61.9%) females. A majority, 523 (59.2%), were in the age range of 51–70 years. Only 40.7% knew that diabetes affects the eyes; 60.2% did not know that good blood sugar control will help prevent eye complications; 41.1% knew they needed to see the eye specialist from time to time but not necessarily for routine check-up. Only 9.1% saw the eye specialists routinely; the remaining 90.9% never went for routine eye check as only 40.72 knew it affects the eyes.

Conclusion:

There was poor perception of the disease and its complications, which led to poor practice such as no regular, periodic eye examinations. There is a dire need for education of the diabetics, building of multidisciplinary effective strategies and policies with the view to decreasing the burden of the disease especially in the developing countries.
Dramske protagonistke in politika spola na odrih sveta
Authors: Toporišič Tomaž
Published: September 2022

In our examination of the selected plays and tragedy, we have focused primarily on gender politics, and more specifically on the phenomenon of female protagonists on the world stage, which is the title of this year’s essay as a part of high-school exit exam in Slovene as the mother tongue. The theme was explored through a comparative analysis of four classics of drama and theatre from antiquity to the second half of the 20th century, focusing on a selection of themes that are still of concern today: the position of women and gender equality in contemporary societies. The women dramatized in the selected plays are representatives of groups that, according to Julia Kristeva’s interpretation, are marginalised in the patriarchal symbolic order and are subjected to various forms of repression of femininity. The determination of biological sex in these plays repeatedly turns out to be socially constructed, as it is based on social norms and regulations. It is the violation of these rules that gives rise to the dramaturgical strategies and gender politics of the plays from antiquity to the present day.
How to research the concept of national identity with child respondents in museum research
Authors: Kolaříková Veronika
Published: September 2022

Museums have been closely linked to national identity since the 19th century. Currently, museums have to cope with the ways they present themselves to visitors properly. Therefore, national identity in a museum has become the centre of research attention. Children are a large group of visitors who come into contact with the national narrative in museums. Involving children in the research of the concept of national identity constructed in the museum can bring many interesting findings. However, research with children is difficult. Especially for beginning researchers or museum staff, who do not have in-depth experience with qualitative research. Thus, the aim of the study is to present possible ways of researching national identity with children. Attention will be drawn to the discussion of which variables and which data collection techniques are possible to examine national identity and it’s concept with children.
Yi Lijun (1934–2022)
Authors: Kamień Joanna
Published: September 2022

On 7 February 2022, Professor Yi Lijun passed away in Beijing. She was the most outstanding Chinese Polish scholar, and was known as the ambassador of Polish literature in China. She was closely linked with the University of Gdańsk. In 2007, she received an honorary doctorate from the University, and she was a member of the Academic Council of the Centre for East Asian Studies at the University of Gdańskand of the scholarly bi-annual journal Gdańsk East Asian Studies.
Yi Lijun was born on 4 December 1934 in the Huang Gang administrative district of Hu Bei Province. She studied in the Department of Chinese Language and Literature at Wuhan University, and studied Polish at the University of Warsaw from 1954 to 1960. After returning to China, Yi Lijun worked for two years as a journalist for Radio Beijing. In 1962, she started work at Beijing Foreign Studies University, where she remained to the end of her academic career.
For many years, she was director of the Department of Polish Language in the Faculty of European Languages of BFSU. She taught several generations of Chinese Polish scholars, who today work at universities, in foreign trade, in culture, in the tourist industry, and in diplomacy. She contributed hugely to the cause of Polish culture in China as a translator, scholar, and promoter of Polish literature. She translated into Chinese the writings of over forty Polish authors of the nineteenth and twentieth centuries. Her list of publications includes more than seventy works in prose and verse, including: Adam Mickiewicz’s Dziady (Forefathers’ Eve), parts III and IV; Henryk Sienkiewicz’s Krzyżacy (The Knights of the Cross), Ogniem i mieczem (With Fire and Sword ), and Potop (The Deluge); Witold Gombrowicz’s Ferdydurke; Olga Tokarczuk’s Prawiek i inne czasy (Primeval and Other Times) and Dom dzienny, dom nocny (House of Day, House of Night); and Wybór klechd i baśni polskich. She also brought to Chinese readers poems by Polish winners of the Nobel Prize, Czesław Miłosz and Wisława Szymborska, and also those of many other poets. Her publications include scores of articles on Polish writers. She edited more than 300 entries on Polish writers and Polish literature for Chinese encyclopedias. Professor Yi Lijun received many Polish state awards in recognition of her achievements, including the Medal for Services to Polish Culture – Gloria Artis, the Knight’s Cross of the Order of Merit of the Republic of Poland, and the Medal of the Commission for National Education.
Effect of Volute Collector on the Performance of Centrifugal Pump Based on Entropy Generation Analysis
Authors: Maitrik Shah  , Beena Baloni  , Salim Channiwala
Published: September 2022

A proper design of centrifugal pumps reduces power loss and improves efficiency. This study aims to investigate and analyze the effect of different volute collector configurations on centrifugal pump performance. Locations of losses are detected using the entropy production rate, whereas the number of losses is evaluated using user-defined codes. Three volute collectors are selected based on their connections with standard pipes. A steady flow numerical analysis is performed to determine the performance parameters of the centrifugal pump and select a modified volute collector design. Comparing the results of experiments on the base and modified volute collectors confirmed that the proper design of the volute collector can help reduce the secondary flow losses at subsequent locations, which reduces the entropy production and losses. As compared to the base pump, the modified volute collector improved the pump efficiency by 3% at the duty flow.
Exploring the Educational Impact of Academic Field Trips over Time
Authors: Parrello Tara , Valentine Colby L.
Published: September 2022

None provided
INCREASING THE CORROSION RESISTANCE OF HEAT-RESISTANT ALLOYS FOR PARTS OF POWER EQUIPMENT
Authors: Vahrusheva V.S. , Hlushkova D.B. , Volchuk V.M. , Nosova T.V. , Mamhur S.I. , Tsokur N.I. , Bagrov V.A. , Demchenko S.V. , Ryzhkov Yu.V. , Scrypnikov V.O.
Published: September 2022

For the manufacture of parts and assemblies of the turbopump unit of details of power equipment, welded joints with corrosion resistant steels and heat-resistant alloys are used, requiring various modes heat treatment to achieve the required level of mechanical properties. In the manufacture of parts and assemblies of details of power equipment at the machine-building enterprises of Ukraine, it became necessary to replace semi-finished products. It is necessary to replace sheet products from high-alloy alloys ХН67МВТЮ and 06Х15Н6МВФБ with one alloy with a high complex of physical and mechanical characteristics. In the work, as a replacement for the applied heat-resistant alloys, Inconel 718 alloy welded to 316L steel. Samples of welded joints, processed according to the recommended mode, showed increased corrosion resistance.
Observations on the diet of Aotus nigriceps (Primates: Cebidae) in an urban and peri-urban area in Rondônia state, Brazil
Authors: Chaves dos Santos João Vitor , De Sousa Lima Alexandre Henrique , André da Costa Tavares  , Pommer Barbosa Raul Afonso , Alvares Oliveira Marcela
Published: September 2022

The black-headed night monkey (Aotus nigriceps) is a predominantly frugivorous nocturnal neotropical primate. As such, records of different dietary items are fundamental. In the present study, we describe the first record of the consumption of Calliandra brevipes inflorescence in the peri-urban, and Cocos nucifera inflorescence, Eugenia uniflora fruits, and arthropods in the urban, region of the city of Porto Velho, in the southwestern Brazilian Amazon
PERAN GURU DALAM MEMBENTUK KARAKTER PERCAYA DIRI ANAK USIA DINI
Authors: Amrillah H.M. Taufik , Yulizah Yosi , Widiyanti Dini
Published: September 2022

This study discusses the role of teachers in shaping self-confidence in early childhood. The teacher is the main role in shaping the character of each child, this shows the teacher must be able to carry out his main role as a guide, motivator, and inspiration. The purpose of this study was to identify and describe the teacher's role in shaping the self-confident character of early childhood. By using qualitative research methods using descriptive qualitative which is defined by describing, with this research is to describe a situation with words. This is very much in line with the problem being studied, because this study analyzes phenomena and facts regarding the role of teachers in shaping the self-confident character of early childhood. With the results of the research that has been analyzed, it is found that the teacher has become a teacher who acts as a guide, motivator, and inspiration during the learning process in the classroom.
The Kinetic Evaluation and DFT Study of Cis-[Pt(Asc)(NH3)2] Complex as an Inhibitor to Type 2 Diabetic Human Amylase
Authors: Al-Rawi Khalid Farouk , Maher Khaldoon Taher , Alajrawy Othman Ibrahim , Maher Firas Taher
Published: September 2022

Several metal complexes and organic compounds and extracted herbs that might be involved in the bio-mechanism of the type 2 diabetes mellitus treatments. This research aims to synthesize a new platinum (II) complex and study its kinetics as an inhibitor for freshly purified amylase from type 2 human diabetics. The amylase enzyme was precipitated from diabetic patients. The complex cis-[Pt(Asc)(NH3)2] was synthesized and characterized experimentally and theoretically by DFT calculations to conclude the structure. Both calculations confirmed the square planar geometry for the prepared complex. The results showed that the complex is more stable and polar than the L-ascorbic acid derivative. Therefore, we suggested that the synthesized Pt(II) complex is appropriate to be examined as an inhibitor for the amylase enzyme. Several concentrations from the Pt(II) complex were prepared for kinetic purposes. Kinetic results have shown that the newly prepared complex has a remarkable inhibition effect on the amylase enzyme. Kinetic parameters were fitted using the Lineweaver–Burk plot. The inhibition reaction was confirmed as a non-competitive inhibitor. Also, an inorganic compound derived from vitamin C was prepared and diagnosed by several spectroscopic methods, and a comparison between the experimental and theoretical data was conducted. The DFT study of the prepared complex gave a useful explanation for the complex and its stability. Thus, an inhibitory effect on the activity of the amylase enzyme was clearly shown by the newly prepared Pt(II) complex. It can be concluded that Pt(II) complex could be used as an amylase inhibitor.
Robust Hybrid Classification Methods and Applications
Authors: Okwonu Friday Zinzendoff , Ahad Nor Aishah , Okoloko Innocent Ejiro , Apanapudor Joshua Sarduana , Kamaruddin Saadi Ahmad , Arunaye Festus Irimisose
Published: September 2022

The sample mean classifier, such as the nearest mean classifier (NMC) and the Bayes classifier, is not robust due to the influence of outliers. Enhancing the robust performance of these methods may result in vital information loss due to weighting or data deletion. The focus of this study is to develop robust hybrid univariate classifiers that do not rely on data weighting or deletion. The following data transformation methods, such as the least square approach (LSA) and linear prediction approach (LPA), are applied to estimate the parameters of interest to achieve the objectives of this study. The LSA and LPA estimates are applied to develop two groups of univariate classifiers. We further applied the predicted estimates from the LSA and LPA methods to develop four hybrid classifiers. These classifiers are applied to investigate whether cattle horn and base width length could be used to determine cattle gender. We also used these classification methods to determine whether shapes could classify banana variety. The NMC, LSA, LPA, and hybrid classifiers showed that cattle gender could be determined using horn length and base width measurement. The analysis further revealed that shapes could determine banana variety. The comparative results using the two data sets demonstrated that all the methods have over 90% performance prediction accuracy. The findings affirmed that the performance of the NMC, LSA, LPA, and the hybrid classifiers satisfy the data-dependent theory and are suitable for classifying agricultural products. Therefore, the proposed methods could be applied to perform classification tasks efficiently in many fields of study.
Analisa Keandalan Sistem Jaringan Distribusi 20 kV Dan Rekonfigurasi Recloser Pada Penyulang Kamal
Authors: Titiek Suheta  , Muhammad Faisal A
Published: September 2022

The increasing population in the Kamal area has improved the demand for electrical energy needs. Consequently, disruptions to the electricity distribution network may happen, such as blackouts in certain areas. The value of the reliability index will increase and not be in accordance with the standards that have been set. For this reason, this study calculated the reliability values of SAIFI and SAIDI on the Kamal feeder using the RIA (Reliability Index Assessment) method and the recloser reconfiguration using the fuzzy logic method. The simulation results indicated that the SAIFI value gained 6.331 times/year, while SAIDI obtained 20.212 hours/year. Based on recloser reconfiguration, the SAIFI value was earned 4.926 times/year, whereas SAIDI got 15.962 hours/year. The best location was located on line nineteen in group three, producing an output value of 0.461.
A close examination of posted speed limits and its compliance on Indian State Highways
Authors: Rao Amudapuram Mohan Rao
Published: September 2022

Road accident is most unwanted thing to happen on a road. Most of the fatal accidents occur due to over speeding. Increase in speed multiplies the risk of accident and severity of injury during accident. Excess speed is defined as the one exceeding the speed limit and driving at a speed unsuitable for the prevailing road and traffic conditions. Controlling the vehicle speed can prevent crashes happening and can reduce the impact when they do occur. Specified speed limits are of huge importance in controlling the road accidents. Speed limits are the maximum legal travel speeds during favorable conditions. The speed limits provide a balance of collision risk, safety and also provide the basis for enforcement. These limits are set with the goal of keeping everyone safe. Twenty six sections of undivided two-lane and four lane divided interurban State Highways are selected in 03 states of India to analyze the speed data to estimate the level of compliance of posted speed limit sign. Operating speed models are developed for the road sections selected in this study using different parameters. The most influencing parameters are found to be shoulder width (SW), percentage of heavy vehicle (%HV) and road side hazard rating (RSH) for medium traffic two lane State Highways. For heavy traffic four lane divided roads, the most influencing parameter is the percentage of heavy traffic only. The study found that 24.6 to 35.81 percent drivers are travelling above speed limit and few are (1.08 to 1.72%) travelling at speed higher than 98th percentile speed also. Based on the results of speed compliance need speed limits are proposed for these highways.
ĐẶC ĐIỂM LÂM SÀNG, XQUANG GÃY PHỨC HỢP GÒ MÁ CUNG TIẾP TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC NĂM 2021 – 2022
Authors: Đức Thành Đậu , Hồng Hà Nguyễn
Published: September 2022

Mục tiêu: Mô tả đặc điểm lâm sàng, xquang của bệnh nhân gãy phức hợp gò má cung tiếp (GMCT) được điều trị tại khoa Phẫu thuật hàm mặt – Tạo hình – Thẩm mỹ, bệnh viện Hữu nghị Việt Đức năm 2021 – 2022. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang trên 305 bệnh nhân được chẩn đoán và điều trị gãy phức hợp GMCT tại khoa Phẫu thuật hàm mặt – Tạo hình – Thẩm mỹ, bệnh viện Việt Đức từ tháng 1/2021 đến tháng 3/2022. Đối tượng nghiên cứu được khai thác tiền sử, khám lâm sàng, chụp xquang để ghi nhận các chỉ số nghiên cứu. Kết quả: Đối tượng nghiên cứu có tuổi trung bình 30,5 ± 11,6 tuổi, tỷ lệ nam/ nữ = 6,8; nguyên nhân chủ yếu do tai nạn giao thông với 94,8%. Về lâm sàng: dấu hiệu đau chói tại điểm gãy chiếm tỷ lệ cao nhất với tỷ lệ 92,8%, tiếp đến là dấu hiệu sưng nề phần mềm (91,8%), bầm tím quanh hốc mắt (90,8%), gián đoạn xương (82,6%), lõm bẹt gò má (69,5%). Về Xquang: 100% sử dụng phim CT scanner. Vể phân loại gãy xương GMCT theo Knight – North, gãy xương cung tiếp đơn thuần chiếm 3,9%, gãy xương GMCT không di lệch chiếm 2,3%, gãy thân xương gò má không xoay chiếm 29,2%, gãy thân xương gò má xoay ra ngoài chiếm 23,6%, gãy thân xương gò má xoay vào trong chiếm 28,5%, gãy xương GMCT phức tạp chiếm 12,5%. Về các tổn thương phối hợp: các tổn thương vùng mặt phối hợp thường gặp là xoang (93,1%), vết thương vùng mặt (57,7%), gãy xương hàm trên (36,1%); các tổn thương cơ quan khác phối hợp gồm chấn thương sọ não chiếm tỷ lệ cao nhất với 36,1%, chấn thương chi cũng chiếm tỷ lệ khá cao với 24,3%, chấn thương ngực là 6,9%, chấn thương bụng là 2,3%, chấn thương cột sống (1,6%). Kết luận: Gãy xương GMCT chủ yếu gặp ở đối tượng nam giới trẻ tuổi, thường từ 16 – 30 tuổi với nguyên nhân chủ yếu là tai nạn giao thông. Triệu chứng lâm sàng thường thường khá đa dạng và được phát hiện đầy đủ trên phim CT scanner. Các tổn thương vùng mặt phối hợp thường gặp là xoang, vết thương vùng mặt, gãy xương hàm trên. Gãy xương GMCT kèm theo các tổn thương ở các cơ quan khác với tỷ lệ khá cao như chấn thương sọ não, chấn thương chi.
ĐÁNH GIÁ CHẤT LƯỢNG CUỘC SỐNG Ở BỆNH NHÂN TRÀO NGƯỢC DẠ DÀY-THỰC QUẢN BẰNG BỘ CÂU HỎI QOLRAD
Authors: Thị Phương Thanh Phạm , Văn Khiên Vũ
Published: September 2022

Mục tiêu: (1) Đánh giá chất lượng cuộc sống của người bệnh trào ngược dạ dày – thực quản (TNDDTQ) bằng bộ câu hỏi QOLRAD. (2) Nhận xét một số yếu tố ảnh hưởng đến chất lượng cuộc sống của người bệnh TNDDTQ. Phương pháp: Nghiên cứu mô tả cắt ngang trên 323 người bệnh TNDDTQ đến khám tại Bệnh viện Đại học Y Hà Nội từ tháng 07-12/2021. Đánh giá chất lượng cuộc sống của bệnh nhân TNDDTQ theo bộ câu hỏi QOLRAD. Kết quả: TNDDTQ ảnh hưởng nhiều nhất đến các lĩnh vực sau: Sức sống (3,75± 1,60),  ăn/uống (4,59±1,46), rối loạn giấc ngủ (4,83±1,71), cảm xúc (5,43±1,43), và thể chất/xã hội (6,09±1,08). Các yếu tố: tuổi với lĩnh vực rối loạn giấc ngủ, BMI với tình trạng ăn/uống, thời gian mắc TNDDTQ với lĩnh vực sức sống, đặc điểm kinh tế và số bữa ăn trong ngày với hầu hết các lĩnh vực chất lượng cuộc sống liên quan có ý nghĩa thống kê (p < 0,05). Kết luận: Bộ câu hỏi QOLRAD có độ tin cậy và có ý nghĩa trong đánh giá tác động của TNDDTQ đến chất lượng cuộc sống sinh hoạt hàng ngày ở bệnh nhân TNDDTQ.
ĐẶC ĐIỂM LÂM SÀNG BỆNH NHÂN THOÁT VỊ ĐĨA ĐỆM CỘT SỐNG THẮT LƯNG TẠI BỆNH VIỆN THỐNG NHẤT
Authors: Đặng Minh Trí Bùi , Tùng Hiệp Bùi , Văn Kha Trần , Vương Vũ Nguyễn
Published: September 2022

Mục tiêu: Mô tả đặc điểm lâm sàng bệnh nhân thoát vị đĩa đệm cột sống thắt lưng tại bệnh viện Thống Nhất. Đối tượng và phương pháp: nghiên cứu mô tả tiến cứu trên 72 bệnh nhân được chẩn đoán thoát vị đĩa đệm cột sống thắt lưng và điều trị tại Bệnh viện Thống Nhất. Kết quả: Trong số các bệnh nhân nghiên cứu, phần lớn các bệnh nhân có thời gian mắc bệnh là trên 1 tháng, thường gặp là từ 6- 12 tháng, khởi phát bệnh đột ngột, liên quan đến các yếu tố chấn thương chiếm tỉ lệ cao. Đau lan theo rễ dây thần kinh chi phối, đau bên trái gặp nhiều hơn so với đau bên phải. Tính chất đau tăng khi vận động, ho, hắt hơi. Chủ yếu là dị cảm và giảm cảm giác chân giảm hoặc mất phản xạ gối, phản xạ gót hoặc rối loạn cả phản xạ gối và gót, goảm sức cơ theo rễ dây thần kinh chi phối. Tỷ lệ teo cơ là 27,5 %. Bệnh nhân có hội chứng cột sống thắt lưng và hội chứng rễ thần kinh thắt lưng cùng chiếm tỷ lệ cao. Kết luận: Trong số các bệnh nhân nghiên cứu, phần lớn các bệnh nhân có thời gian mắc bệnh là trên 1 tháng, khởi phát bệnh đột ngột, liên quan đến các yếu tố chấn thương chiếm tỉ lệ cao. Bệnh nhân có hội chứng cột sống thắt lưng và hội chứng rễ thần kinh thắt lưng cùng chiếm tỷ lệ cao.
YẾU TỐ DUY TRÌ ĐỘNG LỰC LÀM VIỆC CỦA NHÂN VIÊN Y TẾ VÀ MỘT SỐ YẾU TỐ LIÊN QUAN TẠI TRUNG TÂM Y TẾ HUYỆN AN MINH, TỈNH KIÊN GIANG NĂM 2020-2021
Authors: Thị Lý Trần , Văn Nhân Lê , Thị Kim Chi Lê , Quốc Thắng Trần , Quốc Trận Võ , Văn Dũng Đào
Published: September 2022

Đặt vấn đề: Hiệu quả hoạt động của một đơn vị phụ thuộc vào nhiều yếu tố, trong đó nguồn nhân lực là yếu tố vô cùng quan trọng. Đối với các cơ sở y tế, động lực làm việc của nhân viên y tế ảnh hưởng đến chất lượng cung cấp các dịch vụ y tế. Mục tiêu: Mô tả động lực làm việc và phân tích một số yếu tố liên quan đến động lực làm việc của nhân y tế tại Trung tâm Y tế huyện An Minh, tỉnh Kiên Giang, năm 2020-2021. Phương pháp: Điều tra cắt ngang, nghiên cứu định lượng kết hợp định tính. Kết quả: Nghiên cứu thu thập thông tin định lượng từ 270 NVYT tại TTYT An Minh thông qua phiếu phát vấn, thu thập thông tin định tính qua phỏng vấn sâu 08 NVYT. Kết quả nghiên cứu cho thấy tỷ lệ NVYT tại TTYT An Minh có động lực làm việc chưa cao. Kết luận: Tỷ lệ NVYT có động lực làm việc chung (53,7%), yếu tố có động lực cao nhất là bản thân công việc (79,3%), yếu tố có động lực thấp nhất là điều kiện làm việc (35,6%). Một số yếu tố liên quan đến động lực làm việc: trình độ chuyên môn, loại hình lao động và thu nhập trung bình hàng tháng (p<0,05).
NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN VIÊM TUỴ CẤP SAU NỘI SOI MẬT TỤY NGƯỢC DÒNG LẤY SỎI ỐNG MẬT CHỦ
Authors: Hữu Khâm Nguyễn , Quang Huy Dương , Hữu Nhượng Lê , Bá Danh Phan
Published: September 2022

Đặt vấn đề: Nội soi mật tuỵ ngược dòng (ERCP) là một thủ thuật phức tạp, bên cạnh những lợi ích thì thủ thuật này cũng có nhiều biến chứng như chảy máu, thủng tá tràng, viêm tụy cấp (VTC)… Trong đó VTC là một trong những biến chứng sớm hay gặp sau ERCP, mức độ trầm trọng của VTC thể phù nề đến thể hoại tử do liên quan nhiều yếu tố nguy cơ trước, trong can thiệp như: tuổi, giới, giải phẫu cơ Oddi, do can thiệp... Mục tiêu: Nhận xét một số đặc điểm lâm sàng, cận lâm sàng của VTC và xác định một số yếu tố liên quan đến viêm tụy cấp sau can thiệp nội soi mật tụy ngược dòng lấy sỏi ống mật chủ (OMC). Đối tượng và phương pháp: Tiến cứu kết hợp hồi cứu trên 61 bệnh nhân (BN) có biến chứng VTC sau can thiệp ERCP lấy sỏi ống mật chủ từ 8/2020 - 7/2022 tại Bệnh viện quân y 354 và Bệnh viện Bạch Mai. Kết quả: Tuổi trung bình 63,4 ± 17,8 (từ 18-98 tuổi); Nam giới 54,1%, Nữ giới 45,9%. Lâm sàng: đau bụng vùng hạ sườn phải hoặc thượng vị (94,6%), sốt (52,2%), vàng da, niêm mạc (32,5%). Trên phim CT hoặc MRI đường mật: 1 viên sỏi (85,4%). Phần lớn sỏi có kích thước dưới 1 cm (74%), đường kính OMC từ 1-2 cm (82,7%). Có 42,1% bị viêm đường mật cấp tính với mức độ viêm nhẹ và vừa (95%), chỉ có 5% nặng. Nồng độ Amylase ở các bệnh nhân viêm tuỵ cấp khá cao, với trung vị là 529,3 U/l, giá trị lớn nhất ghi nhận được lên tới 5514 U/l. VTC trên nhóm viêm đường mật cấp tính (68,9%) cao hơn so với nhóm không có biến chứng này (36,1%) (p<0,05). VTC trên nhóm có nong bóng là 65,6% và nhóm không nong bóng là 31% (p<0,05), tỉ lệ VTC ở nhóm được đặt stent đường dẫn, viêm tuỵ cấp sau ERCP có sỏi ≥ 1 cm (67,2%) cao hơn nhóm có sỏi < 1cm (16,8%) (p<0,05). Kết luận: VTC là biến chứng sớm hay gặp nhất trong các biến chứng sau nội soi mật tuỵ ngược dòng (ERCP) lấy sỏi OMC.
KẾT QUẢ ĐIỀU TRỊ BƯỚC SAU UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ GIAI ĐOẠN DI CĂN XA BẰNG PHÁC ĐỒ ATEZOLIZUMAB ĐƠN TRỊ
Authors: Huy Thắng Lê , Văn Thái Phạm
Published: September 2022

Mục tiêu nghiên cứu: Đánh giá kết quả điều trị bước sau ung thư phổi không tế bào nhỏ giai đoạn di căn xa bằng Atezolizumab đơn trị. Đối tượng và phương pháp nghiên cứu: Gồm 45 bệnh nhân UTPKTBN được điều trị Atezolizumab đơn trị bước sau tại Bệnh viện K và Trung tâm Ung bướu & Y học hạt nhân Bệnh viện Bạch Mai từ tháng 1/2019 đến tháng 6/2022. Người bệnh được ghi nhận các triệu chứng lâm sàng, các xét nghiệm cận lâm sàng trước và sau điều trị, đánh giá hiệu quả của phác đồ và ghi nhận các tác dụng phụ của phác đồ. Kết quả nghiên cứu: Tỷ lệ đáp ứng là 24,4% tỷ lệ kiểm soát bệnh 64,4%, 35,6% bệnh nhân tiến triển. Trung vị thời gian sống thêm không tiến triển là 3,1 [CI 95%; 2,1-4,7] tháng. Trung vị thời gian sống thêm toàn bộ: 9,5 [ CI 95%; 8,2-14,5] tháng. Không có tác dụng ngoại ý trầm trọng nào được ghi nhận. Kết luận: Kết quả điều trị bằng Atezolizumab đơn trị bước sau cho kết quả tốt, một phương pháp tiềm năng cho những bệnh nhân đã thất bại với các phác đồ hóa chất trước đó.
TÌM HIỂU TỔN THƯƠNG THẬN Ở BỆNH NHÂN XƠ CỨNG BÌ
Authors: Thị Lê Ny Lê , Thị Việt Hà Đặng , Thị Phương Thủy Nguyễn , Gia Tuyển Đỗ , Trung Dũng Nghiêm
Published: September 2022

Mục tiêu: Mô tả đặc điểm lâm sàng, cận lâm sàng của tổn thương thận trong bệnh xơ cứng bì. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả (kết hợp hồi cứu và cắt ngang) gồm 82 bệnh nhân xơ cứng bì (XCB) được chẩn đoán theo tiêu chuẩn của Hội thấp khớp học Mỹ và Hội thấp khớp học Châu Âu (ACR/EULAR 2013), điều trị tại Trung tâm Cơ xương khớp, Trung tâm Thận-Tiết niệu- Lọc máu, bệnh viện Bạch Mai và bệnh viện Da liễu Trung ương từ tháng 1/ 2021 đến tháng 7/ 2022. Kết quả và kết luận: Bệnh hay gặp ở lứa tuổi từ 30-50 tuổi với tỷ lệ mắc bệnh của nữ/ nam = 3,1/1. Tổn thương thận gặp ở 18/82 bệnh nhân, chiếm tỷ lệ 22%, trong đó các biểu hiện của tổn thương thận hay gặp ở các bệnh nhân này là tăng tăng huyết áp (61,1%), phù (33,3%), tiểu ít (33,3%), protein niệu (44,4%), hồng cầu niệu (38,9%).  Chúng tôi ghi nhận 2 trường hợp có cơn bệnh thận kịch phát (CBTKP) đi kèm tổn thương da lan tỏa, tiến triển nhanh. 1 bệnh nhân được điều trị bằng thuốc ức chế men chuyển để kiểm soát huyết áp, 1 bệnh nhân được lọc máu hỗ trợ thành công. Trong nhóm 18 bệnh nhân có tổn thương thận, hay gặp XCB toàn thể với tổn thương xơ cứng da lan tỏa (14/18 bệnh nhân). Nhóm bệnh nhân XCB có tổn thương thận gặp ở độ tuổi lớn hơn, các triệu chứng thiếu máu và tăng huyết áp cũng gặp nhiều hơn so với nhóm bệnh nhân không có tổn thương thận. Bên cạnh đó, trong nhóm này, tỷ lệ bệnh nhân có mức độ dày da trung bình hoặc nặng gặp cao hơn rõ rệt so với bệnh nhân có mức độ dày da nhẹ (p<0,05). Ở nhóm bệnh nhân XCB có tổn thương thận, tỷ lệ gặp tự kháng thể ARN- Polymerase III cao hơn so với ở bệnh nhân xơ cứng bì không có tổn thương thận, với p < 0,05.
Ocular dimensions by three-dimensional magnetic resonance imaging in emmetropic versus myopic school children
Authors: Mohd-Ali Bariah , Chen Low Yu , Shahimin Mizhanim Mohamad , Arif Norlaili , Abdul Hamid Hamzaini , Wan Abdul Halim Wan Haslina , Mokri Siti Salasiah , Baseri Huddin Aqilah , Mohidin Norhani
Published: September 2022

Background: Magnetic resonance imaging (MRI) has been used to investigate eye shapes; however, reports involving children are scarce. This study aimed to determine ocular dimensions, and their correlations with refractive error, using three-dimensional MRI in emmetropic versus myopic children.

Methods: Healthy school children aged < 10 years were invited to take part in this cross-sectional study. Refraction and best-corrected distance visual acuity (BCDVA) were determined using cycloplegic refraction and a logarithm of the minimum angle of resolution (logMAR) chart, respectively. All children underwent MRI using a 3-Tesla whole-body scanner. Quantitative eyeball measurements included the longitudinal axial length (LAL), horizontal width (HW), and vertical height (VH) along the cardinal axes. Correlation analysis was used to determine the association between the level of refractive error and the eyeball dimensions.

Results: A total of 70 eyes from 70 children (35 male, 35 female) with a mean (standard deviation [SD]) age of 8.38 (0.49) years were included and analyzed. Mean (SD) refraction (spherical equivalent, SEQ) and BCDVA were -2.55 (1.45) D and -0.01 (0.06) logMAR, respectively. Ocular dimensions were greater in myopes than in emmetropes (all P < 0.05), with no significant differences according to sex. Mean (SD) ocular dimensions were LAL 24.07 (0.91) mm, HW 23.41 (0.82) mm, and VH 23.70 (0.88) mm for myopes, and LAL 22.69 (0.55) mm, HW 22.65 (0.63) mm, and VH 22.94 (0.69) mm for emmetropes. Significant correlations were noted between SEQ and ocular dimensions, with a greater change in LAL (0.46 mm/D, P < 0.001) than in VH (0.27 mm/D, P < 0.001) and HW (0.22 mm/D, P = 0.001).

Conclusions: Myopic eyeballs are larger than those with emmetropia. The eyeball elongates as myopia increases, with the greatest change in LAL, the least in HW, and an intermediate change in VH. These changes manifest in both sexes at a young age and low level of myopia. These data may serve as a reference for monitoring the development of refractive error in young Malaysian children of Chinese origin.
MUTATIONAL ANALYSIS OF FLT3 AND NPM1 GENES IN THE GROUP OF ADULT PATIENTS WITH MYELODYSPLASTIC SYNDROME AND ACUTE NON-LYMPHOBLASTIC LEUKEMIA
Authors: Silin A. E. , Kozich Zh. M. , Shpudeyko V. K. , Tropashko I. B. , Silina A. A. , Martinkov V. N. , Martynenko S. M. , Skryabin A. M. , Voropayeva A. V.
Published: September 2022

The molecular-genetic analysis of DNA samples extracted from the blood and marrow of 14 patients with myelodysplastic syndrome (refractory anemia with excess blasts) and 52 patients with acute non-lymphoblastic leukemia has been performed. It did not reveal any clinically unfavourable mutations of FLT3 gene in the group of the patients with myelodysplastic syndrome. The frequency rates for FLT3-ITD, FLT3 D835 and NPM1 mutations in the group of the patients with acute non-lymphoblastic leukemia made up 21,2 ± 5,7; 5,8 ± 3,2 and 23,1 ± 5,8 per cent, correspondingly. The subgroup of the patients with acute promyelocytic leukemia (М3) detected more FLT3-ITD mutations while the subgroup with acute myeloblastic leukemia (М1) had more NPM1 gene mutations (most of the cases in association with FLT3-ITD mutation). It was shown that a more sensitive genetic test required the use of both blood and marrow DNA samples.
ILIOLUMBAR LIGAMENT: ANATOMOICAL BASIS FOR A RADIOLOGIST (survey of literature)
Authors: Yurkovsky A. M.
Published: September 2022

It is often difficult to interpret the results of radiodiagnostics studies of iliolumbar ligament due to the variability of its anatomic structure. Taking into consideration the deficiency of this information and its importance for diagnostic purposes, the analysis of the publications dedicated to the clinical and radiation anatomy of the iliolumbar ligament has been carried out.
EVALUATION OF BIOELEKTRET BLOOD PROPERTIES, CLINICAL LABORATORY AND FUNCTIONAL INDICATORS FOR CHD DIAGNOSIS WITH THE USE OF NEURAL NETWORK MODELING
Authors: Nikolayeva N. V.
Published: September 2022

The method of analysis of neural networks offers changes in bioelektret properties of blood and cardiovascular system in the form of attributes ranged to evaluate the probability of CHD, and verification of the functional class of stable angina.
RISK FACTORS FOR THE DEVELOPMENT OF INHIBITOR FORMS OF HEMOPHILIA
Authors: Hoduleva S. A. , Hoteyeva A. A.
Published: September 2022

The aim of the work was a complex assessment of inhibitor forms of hemophilia with the account of patients` age, severity of the disease and variant of hemophilia. The article presents the results of the examination of 47 patients with hemophilia in the presence of the inhibitors to plasmic factors of blood coagulation. 97,5 % patients with hemophilia A and 100 % of the examined patients with hemophilia B revealed a diagnostically considerable increase of the inhibitor level (> 0,6BU/ml). The majority of the patients with hemophilia A and hemophilia B (64 и 86 % correspondingly) diagnosed a mild inhibitor form. The development of the inhibitor form of hemophilia in general did not depend on the patients` age, level of factor deficiency and variant of hemophilia. The plan of dynamic observation of the patients with the inhibitor form has been suggested.
FEATURES OF HEMOSTASIS SYSTEM IN EARLY NEONATAL PERIOD
Authors: Kozlova E. L. , Klimkovich N. N.
Published: September 2022

The article illustrates the problem of hemostatic disorders in early neonatal period. It characterizes the changes which occur in the system of vascular-platelet and coagulation homeostasis in newborns. It also shows the diversity of the hemostasiological test results and analyzes the causes leading to the malfunction of the hemostasis system in newborns. The risk factors of hemorrhagic and thrombotic complications in the neonatal period have been systematized and described.
ASSESSMENT OF GLYCEMIC CONTROL IN PATIENTS WITH DIABETES MELITUS TYPE I AND DEPRESSION
Authors: Navmenova Ya. L.
Published: September 2022

The article gives an assessment of the frequency rate of hypoglycemic states in patients with depression. The patients with depressive states revealed a significantly higher level of anxiety on the HADS scale, a higher HbA1C level, a lower level of minimum glycemia and a longer duration of hypoglycemia. Moreover, the patients with depression observed hypoglycemic states and latent hypoglycemia cases significantly oftener than those without depression.
COMPARATIVE ANALYSIS OF CHRONIC HEART DEFICIENCY WITH PRESERVED AND REDUCED FRACTION OF LEFT VENTRICLE
Authors: Bakalets N. F.
Published: September 2022

The comparative analysis of systolic dysfunction of left ventricle and chronic heart deficiency with preserved and reduced fraction of left ventricle ejection has been conducted. In total, 62 patients with heart failure FC III-IV of NYHA were examined. The group of patients with chronic heart deficiency with preserved fraction of ejection (40% patients) was dominated by elderly women, who had a significantly higher body mass index, as well as diabetes mellitus, anemia. These patients revealed significantly higher creatinine and cholesterol levels and a lower hemoglobin level than in the patients with left ventricular systolic dysfunction.
HEART RATE VARIABILITY (literature review)
Authors: Alejnikova T. V.
Published: September 2022

The set of works is devoted studying of heart rate variability (HRV). Article represents the literature review on the given theme. In it modern representations about heart rate variability as a method estimating a condition of mechanisms of regulation of physiological functions of a human body are stated, classical methods of the analysis and possibility of clinical application are considered. The heart rhythm is the indicator of the deviations arising in vegetative nervous system, and change of a heart rhythm - the earliest prognostic sign of many diseases. In clinical practice analysis of heart rate variability (HRV) finds more and more wide application at selection of optimum doses of preparations taking into account a vegetative tone of an organism and for control of spent therapy.
EXPERIMENTAL MODELS OF RHEUMATOID ARTHRITIS
Authors: Gromyko M. V. , Gritsuk A. I.
Published: September 2022

The review covers and analyzes the most common experimental models of rheumatoid arthritis, i.e. adjuvant-induced, collagen-induced and pristane-induced forms.
THE EFFECT OF HEMODYNAMIC FACTORS ON THE ONSET AND PROGRESSION OF PRIMARY OPEN-ANGLE GLAUCOMA (literature review, part I)
Authors: Dravitsa L. V. , Konoplyanik E. V.
Published: September 2022

Objective: to systematize the present-day conceptions of the effect of hemodynamic factors at level of the whole organism and cerebral blood flow on the onset and development of primary open-angle glaucoma. Key points: 1. General disorders of vascular blood flow cause local changes in eye hemodynamics with the subsequent development of degenerative processes in eye tissues, including the drainage unit and optic nerve. 2. The common risk factors contributing to the development of glaucoma, include violation of systemic blood flow, i.e. arterial hypotension, hypertension, vasospasm, hemodynamic crises, hemorheology disturbances, etc. 3. The structural parts of the eye are sensitive to the parameters of cerebral blood flow. The risk factors for glaucoma development are the lack of cerebral circulation (both arterial and venous circulatory distress), stenotic and atherosclerotic lesions of carotid, ophthalmic, ciliary arteries). 4. The POAG patients reveal the arterial vascular disorders specific to carotid and vertebral abnormalities. Conclusion. Not only local factors, but also the violations of general and cerebral hemodynamics influence the development of glaucoma.
FUNGAL SINUSITIS (literature review)
Authors: Redko D. D. , Shlyaga I. D.
Published: September 2022

The article presents main conceptions about the topical problem of the last decade, i.e. fungal or fungal-bacterial sinusitis. The contemporary data on etiology, pathogenesis features, clinical course, classification, approaches to diagnosis and treatment for fungal sinusitis have been given.
SONOGRAPHIC OF THE POSTERIOR LIGAMENTOUS COMPLEX AT LUMBAR: TOPOGRAFO-ANATOMIC AND METHODICAL ASPECTS
Authors: Yurkovskiy A. M. , Anikeev O. I.
Published: September 2022

Purpose: to define the most convenient for use at ultrasaund of lumbar spin anatomo-topographical reference points, and also to allocate variants of the anatomic structure, potentially capable to affect for efficiency ultrasaund examinations of structures of posterior ligamentous complex. Materials and methods: the publications containing the information on alternative anatomy of lumbar spin, found out in English-speaking resources PubMed, and also Russian-speaking editions are analysed Results. The most convenient are defined for ultrasaund examinations of lumbar spinanatomo-topographical reference points, potentially capable to affect variants of the anatomic structure are allocated for efficiency ultrasaund examinations of a posterior ligamentous complex. Conclusion. Completion methodically ultrasaund researches of frames of back stabilising complex taking into account the expressed topografo-anatomic variability of lumbar department of a column is required.
BIOLOGICAL ASPECTS OF DNA METHYLATION (literature review)
Authors: Fomchenko N. E. , Voropayev E. V.
Published: September 2022

The molecular basis of hereditary pathology is now the most studied problem of medical and molecular genetics. The recent research shows that not only genetic factors may determine the development of pathological process, but also the so-called epigenetic factors including genetic and nongenetic changes in the expression of specific genes without corresponding structural changes in its nucleotide sequence. The role of the epigenetic regulation of gene activity based on abnormal methylation is assigned as one of the genetic causes of many cancers. Methylation is one of DNA modifications leading to a change in its structural and functional status, which variety of biological processes makes it subject of great interest for the study of the influence of the genome methylation on the fundamental processes in living cells.
MORPHOLOGICAL STRUCTURAL FEATURES OF PLACENTAS IN WOMEN WITH PRETERM DELIVERY
Authors: Nedoseykina M. S. , Mishin A. V. , Baranovskaya E. I.
Published: September 2022

In case of preterm delivery in placenta there are a number of pathological changes depending on what have caused them. The possibility of their study is retrospective, when the preterm birth has already occurred. The aim of this research was to ascertain the particular features of pregnancy in women with preterm delivery and early neonatal period of their newborns aimed at the identification of risk factors for the affection of the placenta. All the placenta samples revealed inflammatory changes. Hypoplasia of the placenta is more common in women with preterm delivery. Fetal growth retardation in preterm labor associated with the presence of involution-dystrophic changes and impaired maturation of the villi in the placenta.