bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabolic syndrome, HOMA-IR and adiponectin in obese adolescents
Authors: Widjaja Nur Aisiyah , Prihaningtyas Rendi Aji , Hanindita Meta Herdiana , Handajani Retno , Ugrasena I Dewa Gede
Published: January 2024

Background: Homeostasis model assessment (HOMA) is a method used to measure insulin resistance (IR). Adiponectin is involved in the development of atherosclerosis. Objectives: This study aimed to assess metabolic syndrome (MetS) prevalence in adolescents with obesity; correlate HOMA-IR and IR incidence with MetS biochemical parameters and MetS components; as well as correlate adiponectin levels and hypoadiponectinemia incidence with MetS biochemical parameters and MetS components. Methods: This study was conducted at the Outpatient Installation Unit of Nutrition and Metabolic Diseases, Child Health Department, Dr. Soetomo General District Hospital, Surabaya, Indonesia with a cross-sectional study design. It lasted for nine months and focused on obese adolescents aged 13-18 years. Anthropometric measurements and blood biochemistry analyses were done. HOMA-IR was calculated using the formula [glucose (mg/dL) x Insulin (µu/L)]/405. Results: A total of 216 obese adolescents took part in the study. MetS was found in 81 subjects (37.96%). There was weak correlation between HOMA-IR ​​with anthropometric measurements, lipid profiles, fasting blood glucose, and serum adiponectin levels (p<0.05). IR was found to increase the risk of MetS development by 1.661-times, dyslipidemia by 1.845-times, and abdominal obesity by 3.077-times. IR increased the risk of MetS incidence with more than three IDF criteria by 9.368-times. There was a correlation between adiponectin levels with the HDL-c. Hypoadiponectinemia was correlated with the incidence of MetS, abdominal obesity, and hypertriglyceridemia. It also increased the risk of developing MetS by 2.220-times. There was a positive relationship between IR HOMA value ​​and the anthropometric parameters of obesity and MetS parameters. Conclusions: IR was found to be associated with dyslipidemia, abdominal obesity, and MetS incidence with more than three IDF criteria. There was a relationship between hypoadiponectinemia and waist circumference, hip circumference, HDL-c, and triglycerides. Insulin resistance and hypoadiponectinemia were associated with Mets and hypertriglyceridemia incidence.
Omega 3 supplementation to reduce alpha threonine kinase 1 (AKT1) levels in children with acute lymphoblastic leukemia (ALL) in the induction phase of chemotherapy
Authors: Delina Lini
Published: January 2024

Background: Omega-3 inhibits tumor growth and progression in various cancers, but the mechanisms involved remain unclear. Omega-3 induces apoptosis, promotes cell cycle arrest, and reduces inflammation through various mechanisms, including reduced AKT phosphorylation. AKT is involved in cell growth, proliferation, and apoptosis. Acute lymphoblastic leukemia is one of the most prevalent malignancies in children with low remission levels. PI3K/AKT pathway mutations are found in acute lymphoblastic leukemia. Omega-3 is known to inhibit leukemogenesis through AKT1 signaling pathways. Objectives: To analyze omega-3’s role in AKT1 level reduction in children with acute lymphoblastic leukemia (ALL). Methods: A randomized open label pre- and post-test control group study was conducted on two groups: a treatment group receiving 1,000 mg of omega-3 orally once a day during the chemotherapy protocol’s induction phase; and a control group receiving placebos. AKT1 levels were measured before (day 0) and after the induction phase of chemotherapy was completed (day 43). The statistical analysis included paired t-tests, independent sample t-tests, and chi-square tests. Results: Twenty-six subjects included in this study were divided into 13 subjects in the control group and 13 subjects in the treatment group. There was a significant reduction in AKT levels before and after receiving omega-3 supplementation in the treatment group (p < 0.001). Meanwhile, there was a significant increase in the control group’s AKT1 levels (p< 0.001). Conclusion: Omega-3 supplementation suppressed AKT1 levels.
Minorías étnicas religiosas en Europa
Authors: Fernández Rodríguez José Manuel
Published: January 2024

Esta comunicación tratará sobre las diversas minorías étnicas y religiosas que existen, en especial, en Europa oriental. Para empezar, buscaremos definir las nociones de etnia y minoría, e indagaremos en los orígenes de las minorías y la génesis del mosaico europeo. Luego, haremos una breve presentación histórica de los grupos minoritarios religiosos arraigados en ciertos países de Europa del Este. A continuación, trataremos la cuestión del derecho a ser y a existir de estas minorías y la protección que brinda el derecho europeo e internacional, según algunos organismos e instituciones que se ocupan de la cuestión. Finalizaremos con una serie pistas en torno a los problemas y a los desafíos que presenta un multiculturalismo no plenamente integrado en los valores y en el estilo de vida europeos y su repercusión en el futuro modelo de convivencia europea, en la que está en juego, quizás, la existencia misma de la Unión Europea.
Bowel perforation and peritonitis caused by a jejunal leiomyoma. A rare complication of jejunal leiomyoma
Authors: Perysinakis Iraklis , Spanou Kallirroi , Tamiolakis Dimitrios , Korkolopoulou Penelope , Stamatakis Georgios
Published: January 2024

Small-bowel leiomyomas are rare, usually indolent, benign neoplasms, sporadically associated with complications, mainly including bleeding and obstruction. Herein we report a case of a 78-year-old female patient under high-dose corticosteroid treatment for systemic disease, presenting with clinical signs suggestive of peritonitis. Urgent exploratory laparotomy revealed an intraluminal jejunal mass complicated by bowel perforation and multiple enlarged mesenteric lymph nodes. Microscopic examination of the surgical specimen suggested the presence of a jejunal leiomyoma as the cause of perforation and lymph nodes’ infiltration by Hodgkin lymphoma. The patient died on the 15th post-operative day due to pulmonary complications. To our knowledge, this is the first reported case of a jejunal leiomyoma complicated by bowel perforation and peritonitis. A high index of suspicion for the presence of underlying neoplastic disease should be maintained in cases of non-traumatic small-bowel perforation. Additionally, the potentially detrimental effect of comorbidities on a patient’s outcome should be considered even in the context of successful management of primary disease.
Analysis of the Six Eras of the Creation of the Universe in the Holy Qur'an and the Bible: Semiotic Studies Alfred Jules Ayer
Authors: Zainul Ashri
Published: January 2024

All religions have an explanation about nature creating with their version. Talking about these kinds, this paper was not present to be correct who is true or who is false, but a process of nature creating needed to be explained with science so that it can be accepted by mind and conviction. That can be known by becoming deep through making use of logical positivism semiotics analysis by Alfred Jules Ayer. With the use of library research, comparative study, and semiotics analysis by Alfred J. Ayer, this paper has some findings, namely: comparative about nature created from Al-Qur'an and Bible, just not a doctrine of religion. But, as a result of logical positivism analysis, Alfred J. Ayer explains that nature was created during six periods (time) in Islam, and Christianity, in theology, believed that it was a creation of God. Then, the process of nature's creation during six periods (time) is very long; the truth can be verified by the findings of scientists, namely a genesis of nature created by the Big Bang incident, and then because that is dissociated between earth and sky and engender earth and interplanetary rotation in their pivot after that earth experience evolution and all of the process is ended with creating of mountains, plants, humans, and others.
Associations Among Optimal Lung Cancer Treatment, Clinical Outcomes, and Health Care Utilization in Patients Who Underwent Comprehensive Genomic Profiling
Authors: Powell Adam C. , Yay Donderici Elifnur , Zhang Nicole J. , Forbes Shaun P. , Wiedower Julie , McNeal Amy C. , Hiatt Mark D.
Published: January 2024

Background: Although immune checkpoint inhibitor immunotherapies are contraindicated as first-line treatment of advanced non–small cell lung cancer (NSCLC) in patients with ALK rearrangement and EGFR mutation, many receive them. The purpose of this study was to examine the association between optimal first-line treatment in this population and clinical outcomes. Methods: Claims and genomic data from patients with advanced or metastatic NSCLC were extracted from a nationally representative GuardantINFORM dataset. Patients who had their first claim mentioning advanced or metastatic NSCLC between March 2019 and February 2020 and had ALK rearrangement or EGFR mutation detected by comprehensive genomic profiling were included in this study. Patients were classified as having received optimal or suboptimal first-line treatment. Claims were reviewed to determine real-world time to next treatment, real-world time to discontinuation, and health services utilization (emergency department, inpatient, and outpatient) in the 12 months following first-line treatment initiation. Survival analyses were conducted using Kaplan-Meier plots and Cox proportional hazard models. Health services utilization was compared between the groups using t tests and negative binomial models. Results: Of the 359 patients included, 280 (78.0%) received optimal first-line treatment. Optimally treated patients had longer median real-world time to next treatment (11.2 vs 4.4 months; P<.01) and real-world time to discontinuation (10.4 vs 1.9 months; P<.01). The optimal group had significantly fewer emergency department presentations (0.76 vs 1.27; P<.01) and outpatient visits (22.9 vs 42.7; P<.01) than the suboptimal group but did not significantly differ in inpatient utilization. Adjusted utilization analysis yielded similar findings. Conclusions: Patients with NSCLC who received optimal treatment, as determined by comprehensive genomic profiling using next-generation sequencing–based circulating tumor DNA testing (Guardant360), had significantly superior clinical and utilization outcomes, reinforcing existing guidelines recommending profiling at the onset of treatment.
Reduction in Breast Cancer Death With Adjuvant Chemotherapy Among US Women According to Race, Ethnicity, and the 21-Gene Recurrence Score
Authors: Huang Hsiao-Ching , Calip Gregory S. , Weiss Jennifer , Simons Yael , Gadi V.K. , Danciu Oana C. , Rauscher Garth H. , Hoskins Kent F.
Published: January 2024

Background: We previously showed the 21-gene breast recurrence score (RS) has lower prognostic accuracy for non-Hispanic Black (NHB) compared with non-Hispanic White (NHW) women with estrogen receptor (ER)–positive/HER2-negative breast cancer. The purpose of this study was to determine the clinical validity of the RS for predicting chemotherapy benefit as recommended in the current NCCN Guidelines for Breast Cancer among women from diverse racial/ethnic groups. Methods: Using the SEER Oncotype database, we estimated propensity score–weighted hazard ratios (HRs) and 95% confidence intervals for breast cancer death with chemotherapy for women with ER-positive/HER2-negative, AJCC stages I–II, axillary node–negative, invasive breast cancer according to race/ethnicity. Results: We included 6,033 (8.2%) Asian/Pacific Islander (API), 5,697 (7.8%) NHB, 6,688 (9.1%) Hispanic, and 54,945 (74.9%) NHW women. Breast cancer death was reduced with chemotherapy for NHB (HR, 0.48, 95% CI, 0.28–0.81), Hispanic (HR, 0.48; 95% CI, 0.25–0.94), and NHW (HR, 0.80; 95% CI, 0.65–0.99) women with an RS of 26 to 100. There was a nonsignificant reduction for API women (HR, 0.59; 95% CI, 0.28–1.24). For women with an RS of 11 to 25, there was no reduction in death for any racial/ethnic group. Among women aged ≤50 years, the reduction in breast cancer death with chemotherapy differed according to race (NHB: HR, 0.37 [95% CI, 0.20–0.67]; NHW: HR, 0.56 [95% CI, 0.44–0.74]; Pinteraction for chemotherapy * race <.0499). An exploratory subgroup analysis found that young NHB women may benefit from chemotherapy at a lower RS cutoff than other women. Conclusions: The RS was clinically validated as a predictive biomarker for NHB, Hispanic, and NHW women with ER-positive, axillary node-negative breast cancer, but it may underestimate the benefit of chemotherapy for young NHB women. If this finding is confirmed, the RS cutoff for recommending adjuvant chemotherapy for young NHB women with ER-positive, axillary node-negative breast cancer may need to be lower than for other women.
Do women directors impact the cost of bank financing? Evidence from Australia
Authors: Fernández-Méndez Carlos , Pathan Shams , Durand Robert B.
Published: January 2024

We investigate the effect of women directors on the cost of bank loans for a sample of Australian listed firms during the period 2002-2017. More women on both boards and committees are associated with lower loan spreads, reduced default risk, and improved financial reporting quality. The reduction in loan spread is seen from when the first female director joins the board, and the effect of that is stronger than the effects of additional (second and subsequent) women joining the board. Moreover, women’s leadership status reinforces this effect. Our results are consistent with the idea that female directors exhibit greater risk aversion than male directors, that women are not treated as tokens and are influential—even as a minority group on the board—and that they enhance corporate governance and reporting quality.

Investigamos el efecto de las mujeres consejeras en el coste de los préstamos bancarios para una muestra de empresas australianas que cotizan en bolsa durante el período 2002-2017. Un mayor número de mujeres tanto en los consejos de administración como en los comités se asocia con menores diferenciales de los préstamos, un menor riesgo de impago y una mejor calidad de los informes financieros. La reducción del diferencial de los préstamos se observa desde la primera mujer consejera, y resulta más intensa que los efectos asociados a las siguientes (segunda y siguientes) mujeres incorporadas al consejo. Además, el estatus de liderazgo de la mujer refuerza este efecto. Nuestros resultados son coherentes con las nociones de que las mujeres consejeras muestran una mayor aversión al riesgo que los hombres consejeros, que las mujeres no son tratadas como simbolo siendo influyentes incluso como grupo minoritario en el consejo y que mejoran el gobierno corporativo y la calidad de la información.
Motion Graphics
Authors: San Juan Cañestro Iñaki
Published: January 2024

En el texto se hace un repaso de la animación de gráficos o motion graphics desde un punto de vista profesional. Se presenta el panorama actual del sector y los nuevos retos que surgen para los profesionales como son la adaptación a los nuevos formatos y públicos que habitan en las plataformas digitales, las aplicaciones de los gráficos a nuevos entornos como la realidad virtual (VR) y la realidad aumentada (AR), los nuevos productos como los NFT o la integración de la inteligencia artificial (IA) en la generación de gráficos animados. La visión del autor, profesional de los motion graphics, durante varias décadas, muestra un sector dinámico y cambiante pero con gran proyección.
La voz interior y su relación cognitiva con la voz autorial en la narrativa contemporánea en español
Authors: Mora Vicente Luis
Published: January 2024

El objeto de este texto es analizar la conflictiva relación que se establece en algunas obras narrativas entre varias instancias: la presunta voz autorial, la presunta voz de resonancia del autor en el libro, por lo común desdibujada en un «tú» (Juan Goytisolo, Miguel Ángel Hernández) que no parece tener más horizonte referencial que el propio autor, y una «voz interior» a la que se escucha (cuya ascendencia en nuestra tradición literaria puede remontarse a El Conde Lucanor) y que puede confundirse, o no, con una de las voces anteriormente citadas. Tanto algunas técnicas narrativas como idearios semánticos vienen a complicar esas ecuaciones, como el monólogo interior, el uso de voces esquizoides, el dualismo alma-cuerpo, el juego con los paratextos o la aparición de elementos autobiográficos y autoficcionales. Pese a esas dificultades, el propósito del texto es explorar ese vínculo entre las voces internas y las autoriales en algunas obras narrativas contemporáneas escritas en castellano.
Detrás de máscaras y avatares: la voz encarnada y conectada de Remedios Zafra en sus textos
Authors: Touton Isabelle
Published: January 2024

A partir de diez libros ensayístico, autobiográficos y/o ficticios de Remedios Zafra publicados entre 2005 y 2021, se estudia la función de la metáfora reversible de la máscara, la nebulosa de conceptos que la rodean o preceden (como el de “avatar”) y la intensificación de su uso en sus últimas obras. Desde el ciberfeminismo, Zafra propone pensar los juegos antiautoritarios de una identidad a menudo oculta detrás de pantallas, artefactos electrónicos y personajes-máscaras, como dando cuenta de un yo proteiforme, vulnerable y viajero. Lo hace sin embargo desde un materialismo encarnado, el rechazo a la imposición del orden neoliberal en un sector cultural precarizado y desde la conciencia de que nuestras vísceras y flujos nos determinan tanto como la cara sonriente que las mujeres deben presentar al mundo. Se analiza también como al quitarse y quitar al otro la máscara, autorizándose y desautorizando a los que detienen el poder, la autora abre la puerta a una poética de la obscenidad, de los afectos y de la sororidad en el campo literario para inaugurar un nuevo régimen de representación intelectual.
Arraigo y proyectos de futuro de jóvenes del Delta Bonaerense del Paraná (Argentina)
Authors: Camarero Gimena Paula , Straccia Patricio Hernán
Published: January 2024

Actualmente las migraciones de las juventudes rurales son materia de preocupación social y académica. En Latinoamérica, los estudios sobre jóvenes rurales sostienen que no es posible explicarlos únicamente bajo una racionalidad económica y han comenzado a preguntarse por sus trayectorias singulares. Este artículo tiene por objetivo analizar expectativas y proyectos de futuro de jóvenes estudiantes de dos escuelas secundarias del Delta bonaerense del Paraná, teniendo en cuenta la interseccionalidad de marcadores de generación, género y clase social. La estrategia metodológica involucró la realización de talleres participativos y la técnica de la cápsula del tiempo para relevar sus proyecciones. El material producido por el estudiantado fue analizado en torno a cuatro ejes: actividades principales que proyectan realizar, rubros laborales en los que se insertan, carreras seleccionadas para estudios superiores y lugar de residencia. Así, y a los fines de aportar al debate sobre arraigo juvenil en espacios rurales, se evidenció que la interseccionalidad de marcadores sociales determina posiciones desiguales de partida que inciden en la proyección de trayectorias de futuro disímiles en términos de amplitud de posibilidades, y se constató la importancia de considerar el lugar de residencia como un factor que delimita las alternativas de vida imaginables para las juventudes.
Crime e violência interpessoal em Portugal (c. 1850-1910)
Authors: Joao Vaz Maria
Published: January 2024

Percorrendo a criminalidade registada em Portugal no período mediado entre 1850 e 1910, este estudo procura demonstrar como o recurso à violência interpessoal era um elemento fortemente implantado na sociedade portuguesa, caracterizador de comportamentos que as autoridades, em particular as policiais e judiciais, procuravam contrariar, através da sua repressão e penalização. Desta forma, a lei serviu claramente para procurar implantar uma sociedade em que o recurso à violência, em todas as suas formas e exercida contra quem fosse, se tornasse um comportamento cada vez menos frequente e, quando persistente, fosse classificado como crime.
Penerapan Model Leaning By Doing dalam Meningkatkan Kemampuan Berpikir Kritis Siswa Kelas V Sekolah Dasar
Authors: Damayanti Puji , Firdaus Anugrah Ramadhan , Kelana Jajang Bayu
Published: January 2024

Permasalahan lemahnya kemampuan berpikir kritis siswa dalam pembelajaran, khususnya pada mata pelajaran alam karena rendahnya kinerja siswa dalam pembelajaran dan aktivitas sehari-hari dianggap kurang efektif dalam mengembangkan minat, keterampilan dan potensi siswa. sehingga pendidik dituntut untuk terampil, dapat menciptakan pembelajaran yang kondusif, inovatif, kreatif serta memberikan kesempatan kepada siswa untuk berkolaborasi dengan siswa lain untuk menyelesaikan tugas-tugasnya dengan terstruktur dengan tetap berpegang pada metode pengajaran yang berorientasi pada siswa. Penelitian ini bertujuan untuk mengetahui hasil belajar siswa sekolah dasar dalam kemampuan berpikir kritis. Sedangkan kemampuan berpikir kritis itu sendiri merupakan salah satu kemampuan yang harus dikuasai oleh siswa kelas V sekolah dasar untuk memperoleh kemampuan yang baik dalam pemecahan masalah. Metode yang digunakan adalah mix method untuk meningkatkan kemampuan berpikir kritis. sedangkan Subjek penelitian ini adalah siswa kelas v sebuah Sekolah Dasar Negeri Ciwidara, yang berjumlah 30 siswa, terdiri dari 14 siswa perempuan dan 16 siswa laki-laki. Teknik pengumpulan data menggunakan tes. Berdasarkan hasil penelitian menunjukan kemampuan siswa dalam berpikir kritis dengan perolehan skor 84,3 dan termasuk pada kategori baik setelah menggunakan model Leaning By Doing. Dengan demikian, bahwa hasil berpikir kritis dengan menggunakan metode Leaning By Doing ini menunjukan peningkatan dan dapat dinyatakan telah mencapai tujuan penelitian Sehingga penelitian ini dapat dikatakan berhasil
Propuesta de adaptación de contenidos del área electromecánica para la lengua materna aymara
Authors: Rivas Mamani John Eloy , Callisaya Ticona Julia Eliana
Published: January 2024

El objetivo fue proponer la adaptación de saberes, en tanto la producción de conocimientos nuevos en la lengua originaria aymara, tomando como referencia las herramientas manuales de la especialidad de electromecánica, en la Unidad Educativa Villandrani de la Ciudad de El Alto 1. Metodológicamente fue bajo mixto cuantitativo - cualitativo de tipo descriptivo-explicativo. La población fue 2 maestras del área de comunicación, lenguaje y lengua originaria, 3 maestros del área técnica tecnológica general y la muestra de estudiantes fue reducida a 41. La técnica fue la encuesta con los instrumentos entrevista a profundidad, el cuestionario y un pre-test. Los resultados se centran en la propuesta de la metodología nueva aplicada a la adaptación de saberes. Se concluyó que la misma desarrolló de manera positiva la producción de conocimientos de las herramientas manuales de la especialidad de electromecánica en la lengua originaria aymara y es aplicable en otras áreas tales como mecánica, electrónica y electricidad.
Ételek, hagyományok, örökségesítés
Authors: Báti Anikó
Published: January 2024

Food culture has always had a significant role in determining identity and community cohesion. Food is not only nourishment but also a cultural element connected to the material world and festive and everyday customs in many ways. Dining and individual meals also act as mediators, representing a kind of tool and channel of communication. In the process of social discourse about the past, inclusion, and locality, local communities select, reconstruct, and construct their shared food heritage. The study presents the Hungarian institutional framework for the management, preservation, and transmission of food-related traditions on a national and local level, as well as the practice of heritagization and tradition preservation, based on prominent local examples.
BLOKÇEYN ŞӘBӘKӘSİNİN KOMPONENTLӘRİNİN İŞLӘNMӘSİ İLӘ İNFORMASİYA MÜBADİLӘSİNİN TӘHLÜKӘSİZLİYİ
Authors:   Azerbaijan Technical University, Ağayev Abdulhüseyn
Published: January 2024

Blockchain technology is an emerging technology that has the potential to change the way information is stored and transmitted. Its main components are the concepts of decentralization, transparency and distribution, which, in short, are the absence of any central control system between the source and the destination, the interdependence of the blocks used by the participating parties as a chain, and continuously, the registration and storage, and finally, authorization processes after authentication of the information it needs by means of a key belonging to the original owner, as in asymmetric encryption, with the possibility of any loss and at the time of need, stored at millions of points. The purpose of this summary is to discuss the application of information security for data transmission against cyber attacks in blockchain technology. Different methods of implementing security measures such as encryption, digital signatures and multi-signature transactions, different types of cyber-attacks that blockchain technology is vulnerable to and how to prevent these attacks has also been discussed. Also, the role of smart contracts in ensuring secure data transfer and the importance of developing secure protocols has been emphasized. In terms of security, it has also considered the future of blockchain technology and how it can be used to further increase the security of data transmission.
XARİCİ ÖLKӘ VӘTӘNDAŞLARININ AZӘRBAYCANDA İŞLӘ TӘMİN OLUNMASININ MÖVCUD VӘZİYYӘTİ
Authors:   SOCAR Gas Export Department, Baku, Azerbaijan, Ziyalı Elnurә
Published: January 2024

The purpose of the study is to determine the current situation of employment of foreign citizens in Azerbaijan against the background of the analysis of the international mobility of labor resources. During the research, the theoretical and practical approaches to this problem were analyzed, and the study of international experience in this field was set as the main task. Analysis, comparison, grouping and analogy methods are used in the research work. In the study, the system of statistical indicators used by the author to interpret the characteristics of the international mobility of labor resources and the sources of their formation were compared and clarified and analyzed and systematized. Determining the deficiencies in the statistical indicators used to determine the positive and negative impact of the international mobility of labor resources on the socio-economic development of Azerbaijan reflects the scientific novelty of the research. As a result of the research, suggestions were made on the regulation of the international mobility of labor resources of practical importance, and the improvement of statistical indicators in the regulation of this problem in our country was noted.
Comparative Analysis of Variance Estimation Methods in Two-Phase Sampling: A Focus on Regression-cum-Exponential Estimators with Multiple Auxiliaries
Authors: Asghar Amber , Sanaullah Aamir , Khan Hina , Hanif Muhammad
Published: January 2024

In this study, we introduce a regression-cum-exponential estimator designed for estimating population variance. Specifically, we focus on the estimation of unknown population variance in a two-phase sampling setup, considering the use of multiple auxiliary variables. We derive and discuss various cases pertaining to this estimation framework. Additionally, we compare the asymptotic properties of existing approaches with those of our proposed estimator. This allows us to assess the performance and efficiency of the different methods. Finally, we conduct a simulation study to evaluate the performance of our proposed estimator in finite samples, specifically utilizing multi-auxiliary variables. This empirical analysis provides insights into the practical effectiveness of the estimators.
Effect of Economic Policy Uncertainty on Exchange Rate Volatility in Pakistan
Authors: Shair Waqas , Ahmad Naveed , Tayyab Muhammad , Ishaq Iqra
Published: January 2024

This study examines the effect of economic policy uncertainty on Pakistan’s exchange rate. Pakistan’s exchange rate always remains under pressure due to the widening inflow-outflow gap in foreign exchange. The volatile exchange rates make it harder for businesses to invest and make inflation more uncertain, which ultimately slows down productivity and GDP growth. Due to the close linkages of the exchange rate with the economic indicators, it is required to examine the effect of different economic variables on the exchange rate and its volatility by incorporating the role of economic policy uncertainty. The study uses the sample of Jan 2011 to Dec 2022 for the empirical results. The study employs the EGARCH model for empirical results. The aftermaths of the mean equation of the EGARCH model suggest that economic policy uncertainty has a positive effect on Pakistan’s exchange rate. Moreover, an increase in the economic policy uncertainty scale, increases the volatility in Pakistan’s exchange rate. The primary source of exchange rate volatility is the nominal variable rather than the real variables. On the basis of the study’s findings, certain relevant recommendations were given in order to stabilize the foreign exchange market in Pakistan.
Impact of Financial Literacy on Access to Finance and Firm Performance: An Analysis of Growing Industry Cluster in Pakistan
Authors: Khalid Muhammad Waleed , Wahga Aqueel Imtiaz , Chaudhary Muhammad Gulzaib , Majid Safyan , Awais Muhammad
Published: January 2024

The purpose of the study is to examine the significance of financial literacy on the relationship between access to finance and firm performance. In this study, the mediating role of financial literacy is investigated through a questionnaire distributed in the electric fitting sector in Sargodha. Electric fitting sector is a growing industry cluster in Sargodha, Pakistan which has experienced exponential growth during the past few years. However, limited access to finance has become a big hurdle in its growth. This study sheds light on the importance of financial literacy for owners and managers to increase their access to financial products and services to enhance business performance and growth. The study provides a solid foundation for academicians and policymakers to take essential measures that can promote the financial literacy especially in those sectors that are in the growth phase and require the attention from the national government to compete in the global economy.
Addressing User Concerns: A Qualitative Study on Data Privacy in Mobile Banking
Authors: Mushtaq Naila , Suleman Shama , Qayyum Abdul
Published: January 2024

The purpose of this study is to give evidence that sheds light on the complexities of data privacy problems in mobile banking within the setting of Pakistan. Trust plays a vital role, which is linked with socio-cultural dynamics, user experience, and regulatory knowledge, according to the results of a thematic analysis of in-depth interviews and focus group discussions from various ranges of participants. In light of these findings, it is imperative that financial institutions modify their mobile banking services so that they are in line with the values of the local community, place notable importance on open and honest communication, and adjust to the regulatory landscape. Although the findings contribute to the improvement of security and the promotion of self-confidence in Karachi's digital economic environment, it is very important to recognize the limits of the study, which include the qualitative character of the research and the possibility of selection bias.
In Our Neighbours' Soil Our Anzacs Sleep
Authors: Rosenzweig Paul A
Published: January 2024

The Sarawak Heroes Memorial Park in Kuching contains a black marble plaque, installed on 29 August 2016, honouring the Australian military personnel who died during the Indonesian Confrontation with Malaysia. Incomplete records however, led to this plaque containing minor errors and omissions. Three years later, as a member of the South Australia and Northern Territory Branch of the National Malaya and Borneo Veterans Association of Australia Inc, I was invited to deliver a commemorative address for Malaya-Borneo Veterans Day in Kuching on 29 August 2019. This presented the opportunity to extensively research the fallen, and a new plaque was installed prior to this ceremony. My address, included here, drew attention to the 50 Australian fallen from the Malayan wars who remain buried overseas, acknowledging Malaysia and Singapore for looking after our ‘Anzacs’. In particular, of the Australians who died during Confrontation, I noted that eight died in Sarawak (while a further three died after being evacuated from Sarawak). This paper includes this commemorative address, followed by an analysis of the circumstances of each of the eleven Australian defenders of Sarawak in 1965-66 who lost their lives. Concluding this research, the graves of the Australian fallen in Kranji Military Cemetery in Singapore were visited and photographed in December 2019, including the four Australian soldiers who died in Sarawak and remain buried overseas. The significance of the 2019 ceremony in Kuching has been heightened by the inability of veterans to schedule any further reunion visits because of the coronavirus pandemic.
Verbum Interius
Authors: Guna Fransiskus
Published: January 2024

Thomas Aquinas, in one or another way, inherits from Augustine of Hippo a philosophical and theological patrimony that has a great impact on the doctrine of the church. The influence of Augustine on Aquinas which is in turn called Aquinas’s Augustinianism is informed by Aristotle’s thought. One of the Augustinian theological heritage that developed by Aquinas is the teaching of  the Word that is the second person in the Trinity. Althought full of controversy, Aquinas stands confirmed in using Aristotle’s epistemology as lens for reading Augustine’s teaching; and, in turn, he sets up an insightful theological synthesis. This article is traying to show how far even how good Aquinas works on  the concept of word both in theological and philosophical sense.
TINJAUAN TEORI KONSELING PADA PRAKTIK PERJODOHAN DAN DAMPAKNYA TERHADAP POTENSI KDRT
Authors: Afrilian Andre
Published: January 2024

Perjodohan merupakan praktik yang banyak dilakukan oleh masyarakat dalam upaya menikahkan anak keturunan kepada seseorang yang dianggap telah dikenal baik. Namun tidak sedikit praktik perjodohan ini justru berujung kepada sesuatu yang negatif berupa KDRT karena sulit dalam menyesuaikan diri kepada orang baru yang belum dikenal pribadinya, Teori konseling menjadi fokus utama dalam upaya pemahaman dan penanganan masalah ini. Dengan memanfaatkan pendekatan konseling, artikel ini menyelidiki hubungan antara ketidaksetujuan dalam perjodohan dan meningkatnya risiko KDRT. Melalui tinjauan literatur, studi kasus, dan analisis teoritis, artikel ini membahas strategi konseling yang dapat digunakan untuk meredakan ketegangan dalam hubungan perjodohan dan mencegah eskalasi menjadi KDRT. Kesimpulannya, teori konseling membuka ruang untuk pemahaman mendalam mengenai dinamika perjodohan dan KDRT, sambil memberikan panduan praktis untuk intervensi konseling yang efektif dalam konteks ini.
Era 4.0 Curriculum Development Design
Authors: Andri Yuliandi  , Desmiarni  , Nizwardi Jalinus
Published: January 2024

In facing the era of the Fourth Industrial Revolution, curriculum development design becomes crucial to ensure relevant and competitive education. This journal explores the concepts, strategies, and challenges in designing a curriculum that integrates the learning needs of the digital era. The primary focus is on incorporating advanced technologies, such as the Internet of Things (IoT), to ensure learners have a profound understanding of these concepts and can apply them in real-world contexts. This research is a literature review, concluding that the design of 4.0 era curriculum development must be proactive, innovative, and centered on developing competencies that encompass both technical and non-technical aspects. Consequently, education can make a significant contribution to shaping individuals who are ready to compete and adapt in the ongoing digital transformation era
Analysis and Evaluation of the Business Innovation Strategy: A Case Study of Apple Inc.
Authors: Siahaan Marlina
Published: January 2024

Studying business innovation at Apple Inc. involves examining the company's past accomplishments and analyzing the strategies, processes, and underlying beliefs that underpin this innovation. This research tries to uncover the various factors contributing to Apple's success in introducing groundbreaking commercial innovations that consistently push the limits of the technology sector. This study did a comprehensive descriptive analysis to investigate information regarding Apple's business innovation through in-depth case study analysis. Apple's business innovation extends beyond tangible items to encompass the ecosystem and total customer experience. Apple revolutionizes our interaction with technology through its integrated strategy, emphasis on design, and astute market analysis. However, there are ongoing difficulties in sustaining levels of innovation, being competitive, and retaining client loyalty in this constantly evolving era.
Investigation of the prevalence of community-acquired and hospital-acquired pneumonia in patients referred to Sadri Ibn Sina Hospital in 1401
Authors:   Department of Physiology, Faculty of Medicine, Khatam-Al-Nabieen University, Ghazni, Afghanistan., Danishyar Amanullah , Sadat Seyed Abolghasem ,   Department of Physiology, Faculty of Medicine, Khatam-Al-Nabieen University, Ghazni, Afghanistan., Mahdizada Hamidullah ,   Department of Physiology, Faculty of Medicine, Khatam-Al-Nabieen University, Ghazni, Afghanistan.
Published: January 2024

Background: Pneumonia is the sixth cause of death and the most common infectious syndrome associated with death. Most cases of pneumonia are caused by microorganisms. We evaluated the prevalence and epidemiology of community-acquired pneumonia in Sadri Ibn Sina Hospital in 1401. Methods: This cross-sectional-descriptive study was conducted from the beginning to the end of 1401 on the files of patients referred to the Chest Department of Ibn Sina Hospital. Results: 431 patients were examined for the final analysis. This research included 228 men and 203 women. The mean age of the subjects was 59 years. Most of the studied patients were from Kabul Province. Among the subjects studied, smoked, patients had a history of alcohol consumption, and patients had a history of hospitalization less than one week Conclusion: According to studies, hospital-acquired pneumonia is the second most common hospital infection and it happens abundantly in the intensive-care departments..The results of a study in Europe have shown that hospital-acquired pneumonia occurs in 47% of all infections in the intensive care unit. In our study (52.9%) patients had a history of hospitalization less than one week.
Recombinant vaccines in the control of tick-borne diseases: a systematic review
Authors:   Department of Biology and Microbiology, Faculty of Medical Technology, Khatam -Al Nabieen University, Kabul, Afghanistan, Hussaini Dawood
Published: January 2024

Introduction: Ticks are important ectoparasites that eat blood from various animals and sometimes human hosts and this eating causes direct disease or transmission of microorganisms. Investigation and reporting of human bites, vaccines, and treatments can be effective in preventing and promoting human health. Therefore, this study investigated recombinant vaccines for the control of tick-borne diseases. Materials and Methods: The necessary data for this review were obtained solely from the research articles published by 2022 based on databases including the Iran Research Information System, SID, Magiran, PubMed, Web of Science, Scopus, and Science Direct. Results: This study showed that the extraction of numerous articles in the regulation of many types of recombinant vaccines, ticks, and tick-borne diseases is important. Conclusion: Tick-borne diseases are an economic and health problem in the world and have many destructive effects on humans and animals. Recombinant vaccines are available to control a variety of mites and some tick-borne diseases such as Lyme disease, encephalitis, and Crimean-Congo fever. However, new vaccines need to be developed to reduce tick pathogenicity.
Les pauvres et le droit civil : essai sur la production du savoir juridique
Authors: Bahary-Dionne Alexandra , Picotte Marc-Antoine
Published: January 2024

À partir de l’analyse des sources du droit des obligations et du droit des biens, cet article examine comment les sources du droit civil, malgré la vocation universaliste de ce dernier, reflètent avant tout les enjeux juridiques vécus par les personnes morales et les personnes physiques aisées. Il propose que cette tendance s’explique principalement par des inégalités structurelles et épistémiques dans la production du savoir juridique. Effectivement, les procédés de constitution du savoir juridique, les inégalités d’accès aux tribunaux, de même que le statut social des personnes autorisées à produire les normes civilistes ainsi que le savoir sur ces normes sont des contraintes. Ces dernières façonnent considérablement le type d’enjeux, de protagonistes et de visions du monde susceptibles de percoler afin de constituer ce savoir. En découle alors une invisibilité marquée des personnes pauvres en son sein. Nous proposons ultimement une réflexion en droit civil sur les manières de mieux refléter leurs expériences en dépit des contraintes socioéconomiques et épistémiques exposées.
Численное моделирование изменения рельефа дна водоема при наличии гравитационных волн
Authors: Сухинов Александр Иванович , Холодков Валентин Владимирович , Проценко Елена Анатольевна , Проценко Софья Владимировна , Панасенко Наталья Дмитриевна
Published: January 2024

The issues concerning the construction of precision mathematical models of hydrodynamics of wave processes and relief formation and their adaptation to variable climatic conditions and geographical features are discussed. The incompleteness of initial information is characteristic of the new problems considered in the paper, and this difficulty is overcome by using the remote sensing and cadastral survey data. The complex of algorithms created by the authors includes raster models of a dynamically changing bottom relief that are based on the results of cadastral surveys, remote sensing data and numerical simulation results. The mathematical model of transport of bottom materials makes it possible to predict the bottom relief dynamics due to the movement of water and multicomponent solid particles and to take into account soil porosity, critical shear stress values at which sediment movement begins, turbulent exchange, bottom geometry transformation, wind currents, and bottom friction. The programs developed on the basis of a set of algorithms are used to perform predictive calculations of the processes of coastal erosion and reconstruction of the bottom relief. Using the programs, the complex geometry of the reservoir bottom is represented by a raster model that takes into account the data of cadastral surveys and remote sensing, the type and characteristics of the source of water fluctuations, and the direction and speed of wind. When analyzing the state of a water body as a whole, the characteristic features of natural processes, in particular, the spatial and temporal variability of the bottom relief, are considered. Modeling the transport of sediments has shown that, in the course of time, they are formed near the coastal zone, which leads to a decrease in the slope of its bottom and a gradual shallowing of the reservoir.
Yakut National Holiday – Ysyakh: traditions and modernity
Authors: Gogolev Anatolii Ignatevich , Yakovleva Kapitolina Maksimovna , Mikhailova Sargylana Mikhailovna , Mikhailova Saina Andreevna
Published: January 2024

The subject of the study is the transformation of rites and rituals in the structural part of the traditional Ysyakh holiday among the Yakuts. In the traditional sense of the Yakuts, ysyakh was a calendar and ceremonial holiday after which the economic cattle breeding year began. In addition, the traditional holiday vividly reflected the religious ideas of the Yakuts – receiving blessings from the bright deities of Ayyy. During the genesis and transformation of this holiday through the prism of historical periods, the appearance of the holiday and religious beliefs are transformed, but the use of ritual utensils and food remains within the framework of rituals. In the work, the subject of research is mainly revealed through the prism of tradition and modernity. The work is divided into the structure and rituals of the traditional holiday in the first part, in the second half the authors' materials on the modern celebration of Ysyakh in 2022. The main methods in the article are diachronic, the method of included observation, as well as interviewing. The novelty of the study lies in the fact that the national holiday Ysyakh is considered within the framework of its genesis, from tradition to modernity. Today, the holiday is an important ethnocultural and regional event in the territory of the Republic of Sakha (Yakutia), the work contains relevant materials from the Olonkho Ysyakhs and the local urban district in the territory of the Vilyui group of uluses for 2022. As a result of the work, the authors conclude that despite the historical conditions through which this holiday passed, it retained its original idea: the beginning of a new economic cycle, the birth of nature, the worship of the bright deities of Ayyy, the preservation of the sacredness of food in rituals and rituals.
Research on intuitionistic fuzzy implications. Part 3
Authors:   Faculty of Mathematics and Informatics, Sofia University, Angelova Nora , Atanassov Krassimir ,   Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences,   Prof. Dr. Asen Zlatarov University, Atanassova Vassia ,   Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
Published: January 2024

Continuing the research from [1, 2], here we give the lists of the intuitionistic fuzzy implications, introduced in [2], that satisfy at least one of two forms of Modus Ponens (MP) – a standard and a new one, called “mixed”, forms. We show the relationship between every two of these implications that satisfy the mixed form of MP.