bluuebunny/crossref_metadata_2025 huggingface dataset:
Superior Degradation characteristics of industrial wastewater treated by Biological and 3D Electrochemical Coupling Process
Authors: Zhu Guixian , Feng Qiang , Li Huan , Zhang Zhewei , Xu Hao , Jia Longfei
Published: August 2024

The performance of the combined biological and three-dimensional electrochemical treatments was studied for the industrial wastewater from sewage treatment plant. The process parameters were investigated.Result showed that the system could remove over 99.13% COD,63.88% TN,99.42% TP and 25.0% NH3-N in 2h. Under the operating conditions of voltage 8V, electrolysis 120min, addition of 2000mg/L electrolyte KCl and 30g industrial waste steel slag, the degradation of pollutants is effectively improved. And through economic analysis, it can be calculated that it only costs 2.2CNY/t to process one ton of industrial wastewater. The experimental results not only meet the water discharge standards, but also pave the way for developing techniques with high efficiency, economy, low energy consumption and universal use.
Signatures of under-the-barrier dynamics in a tunneling electron wavepacket
Authors: Hatsagortsyan Karen Z.
Published: August 2024

The formation of the electron wavepacket in strong field tunneling ionization is investigated. We examine the role of the under-the-barrier recollisions in shaping the phase of the photoelectron wavepacket, which in particular, is responsible for the tunneling time delay. A general analytical relationship between the phase of the tunneled electron wavepacket and the tunneling rate is established. We demonstrate the enhancement of the amplitude of the recolliding path and the wavepacket phase shift due to the Coulomb field effect of the atomic potential, which counteracts the lateral spreading of the tunneling wavepacket during the sub-barrier propagation. Our analysis employs the dressed bound state in the laser field in the adiabatic approximation. The insight gained from our findings will facilitate the free electron wavepacket synthesis via strong field ionization in sculptured laser fields.
The Effect of Lipoprotein Cholesterol Levels and Particle Sizes on HIV Cell Entry via gp41 C34: Insights from Mendelian Randomization Analysis
Authors: Qing Liu , Yanzhao Zhang
Published: August 2024

Background: The gp41 C34 peptide, which is part of the HIV envelope glycoprotein, is crucial for HIV entry into host cells because it facilitates membrane fusion and serves as a biomarker for viral replication. Lipoproteins, including HDL, LDL, IDL, VLDL, and chylomicrons, affect HIV infection via their cholesterol levels and particle sizes, but their causal relationships with HIV remain unclear.
Methods: Utilizing the Mendelian randomization (MR) approach to infer causality, this study leverages genetic data from the UK Biobank (115,082 individuals) and the KORA cohort (997 individuals) to explore the causal relationships between 39 lipoprotein traits (cholesterol levels and subtype concentrations of different particle sizes) and gp41 C34 expression. The primary MR method employed was the random-effect inverse variance weighted (IVW) approach. To ensure robust and reliable causal inference, multiple sensitivity analyses, including weighted median, MR‒Egger regression, simple mode, weighted mode, and leave-one-out analyses, were conducted.
Results: Elevated HDL cholesterol levels were significantly associated with reduced gp41 C34 expression (IVW: β = -0.61, SE = 0.186, p = 1.25e-4, FDR = 0.004), suggesting a protective role of HDL cholesterol in HIV infection. Higher HDL particle concentrations were also inversely associated with gp41 C34 expression (IVW: β = -0.549, SE = 0.202, p = 0.007, FDR = 0.032). Increased cholesterol levels in large HDL particles were significantly inversely related to gp41 C34 expression (IVW: β = -0.46, SE = 0.16, p = 0.004, FDR = 0.03). Similarly, higher concentrations of medium HDL particles were linked to lower gp41 C34 expression (IVW: β = -0.473, SE = 0.166, p = 0.005, FDR = 0.028).
No significant causal relationships were found between gp41 C34 expression and the cholesterol levels or sizes of IDL, LDL, or VLDL particles or chylomicrons. Consequently, these lipoprotein particles are unlikely to influence gp41 C34 expression and HIV cell entry.
Conclusion: HDL cholesterol and HDL particle concentrations, particularly large and medium HDL particles, play a protective role against HIV cell entry by reducing gp41 C34 expression. Other lipoprotein particles do not show significant causal relationships, indicating that specific lipid traits modulate HIV entry mechanisms. These findings enhance our understanding of the influence of lipoprotein traits on HIV infection and persistence.
Non-stationarity of extreme rainfall and its impact assessment in the north-eastern part of India
Authors: Agarwal Shivam , Debbarma Nilotpal , Roy Parthajit , Choudhury Parthasarathi
Published: August 2024

This study investigates the variability in extreme rainfall in northeast India using stationary and non-stationary frequency analysis. Study identified non-stationarity in the annual maximum daily rainfall time series in northeast India, and it was shown that the non-stationary models exhibited more accurate results compared to modelling the series on the assumption of stationarity. Genetic algorithm is employed as optimization algorithm for parameter estimation in the method of maximum likelihood estimation of parameters hereby referred as MLE-GA. The results demonstrate better non-stationary parameter fitting using MLE-GA approach for GEV and PE3 distributions. Results obtained found that all the twelve rainfall stations considered in the region show significant amount of non-stationarity with values ranging from negative impact of -31.97% to positive impact of 38.6% for return period of 100 years. Overall, the research findings indicate non-stationarity in the frequency analysis of extreme rainfall series to have a significant impact on the northeastern region as a whole, and non-stationary modelling is more beneficial and reliable for any water management studies under climate change in the region.
Confidence intervals and one sample-based hypothesis testing for Cronbach’s α coefficient for interval-valued data
Authors: García-García José , Lubiano María Asunción
Published: August 2024

The definition of the well-known Cronbach's α coefficient has been recently extended to measure the internal consistency of interval-valued scale-based items in questionnaires. Although some of its main properties have already been studied, no inferential technique has yet been proposed to analyze its population value. In this paper, large sample theory and bootstrap procedures are used to obtain one sample-based confidence intervals and perform hypothesis testing for the population Cronbach α coefficient for interval-valued data. The asymptotic correctness and consistency of the suggested methods is theoretically derived by analyzing the limit distribution of the sample and bootstrap analogue estimators of such extended reliability index. In addition, some simulation studies are conducted to empirically investigate the performance of the proposed confidence intervals and hypothesis tests, which is also illustrated through a real-life example.
Enhancing the physician-scientist workforce: evaluating a mentored research program for medical students’ research competencies and intentions
Authors: Piercy Brooke , Miovsky Nicole , Singh Harinder , Afghani Behnoosh , Schneider Margaret
Published: August 2024

Background: The growing recognition of the need to incorporate scientific discoveries into healthcare decisions underscores an urgency for a robust physician-scientist workforce to advance translational research. Despite the correlation between medical students' research engagement and their academic productivity and success, significant gaps remain in the scientific workforce exacerbated by the "leaky pipeline" phenomenon from medical school to academic medicine, where potential physician-scientists veer away from research careers.
The purpose of this study was to assess the effectiveness of a structured mentored research program for enhancing medical students' research competencies and sustaining their interest in research careers, thereby potentially enhancing the physician-scientist workforce.
Methods: The Medical Student Research Program (MSRP) implemented at the University of California, Irvine (UCI) was designed to provide comprehensive research training and support to medical students through a series of structured lectures, mentorship by dedicated faculty, and administrative support for research activities. Students were surveyed upon enrollment and one year later to assess the change in research competencies from baseline to follow-up (paired samples t-test), students’ intent to use research in clinical practice (paired samples t-test), and their intent to conduct research in the future (McNemar’s test and McNemar Bowker test).
Results: Preliminary evaluations indicated that the MSRP enhanced students' research competencies and has the potential to enhance medical students’ research skills. However, similar to national trends, there was a decrease in students' intentions to engage with research in their future clinical career.
Conclusions: Our preliminary findings demonstrate MSRP students’ enhanced research competencies during the first year of the program. However, the decline in students’ intentions to engage in future research highlights the need for continued innovation in research training programs to sustain future intent to conduct research, in turn helping to address the “leaky pipeline” in the physician-scientist workforce. Future studies should focus on mid and long-term outcomes to fully assess research program impact on the physician-scientist pipeline and on integrating such programs more broadly into medical education.
A high power efficiency high power supply rejection LDO with fast-transient response
Authors: Cao Kunbo , Xu Yong , Lu Wandi , Li Wenqi , Li Ziyue
Published: August 2024

In this paper, a SMIC 0.18µm BCD process low-dropout regulator (LDO) with high power efficiency, high power supply rejection (PSR) and fast-transient response is proposed for power management modules in RF energy harvesting systems. A buffer and pole-zero tracking structure are added to achieve only one dominate pole in the unit gain bandwidth (UGB). Simulation results show that the maximum power efficiency of LDO achieves 96.1% and it consumes 18µA quiescent current, delivering a load current range from 0-30mA over a 10µF load. The overshoot voltage is 0.14% of output voltage and the recovery time is less than 3.2µs when the load is varied from no-load to full-load, and the PSR is better than − 47dB at 1MHz.
The divergence of DHN-derived melanin pathways in Metarhizium robertsii
Authors: Xie Linan , Liu Yang , Zhang Yujie , Chen Kang , Yue Qun , Wang Chen , Dun Baoqing , Xu Yuquan , Zhang Liwen
Published: August 2024

The important role of dihydroxynaphthalene-(DHN) melanin in enhancing fungal stress resistance and its importance in fungal development and pathogenicity are well-established. This melanin also aids biocontrol fungi in surviving in the environment and effectively infecting insects. However, the biosynthetic origin of melanin in the biocontrol agents, Metarhizium spp., has remained elusive due to the complexity resulting from the divergence of two DHN-like biosynthetic pathways. Through the heterologous expression of biosynthetic enzymes from these two pathways in baker’s yeast Saccharomyces cerevisiae, we have confirmed the presence of DHN biosynthesis in M. roberstii, and discovered a novel naphthopyrone intermediate that can produce a different type of pigment. These two pigment biosynthetic pathways differ in terms of polyketide intermediate structures and subsequent modification steps. Stress resistance studies using recombinant yeast cells have demonstrated that both DHN and its intermediates confer resistance against UV light prior to polymerization; a similar result was observed for its naphthopyrone counterpart. This study contributes to the understanding of the intricate and diverse biosynthetic mechanisms of fungal melanin and has the potential to enhance the application efficiency of biocontrol fungi such as Metarhizium spp. in agriculture.
Innovative Deep Learning-Based CEA-MMSA Framework for Cultural Emotion Analysis of Tamil and Sanskrit Siddha Palm Leaf Manuscripts
Authors: Yokesh R.Geethanjali , Angadevar A.Valarmathi
Published: August 2024

Tamil palm leaf manuscripts serve as invaluable cultural heritage repositories, housing a wealth of ancient wisdom spanning medical prescriptions and spiritual hymns. However, their profound significance is matched by the complexity of deciphering the sentiments they convey, attributed to their multimodal (text and visual content) and multilingual (Tamil and Sanskrit) nature. This study presents a Deep Learning-Based Cultural Emotion Analyzer (CEA-MMSA) designed for the multimodal and multilingual sentiment analysis of Tamil and Sanskrit Siddha palm leaf manuscripts. These manuscripts are invaluable cultural artifacts, containing ancient wisdom in complex textual and visual formats. Our innovative approach leverages Vision Transformers (ViTs) for visual sentiment analysis and Gated Recurrent Units (GRUs) with attention mechanisms for textual sentiment analysis, facilitating a nuanced understanding of emotional content. The proposed multimodal fusion model enhances data interpretation by integrating textual and visual sentiments, addressing the intricacies of the manuscripts' linguistic aspects. Empirical results demonstrate the efficacy of our methodology, achieving an accuracy of 97.38%, with precision at 96.87%, recall at 95.34%, and an F1 score of 95.37%. This advancement not only enriches the study and preservation of these manuscripts but also illuminates the emotional and cultural narratives encapsulated within them.
The risk of believing that emotions are bad and uncontrollable: association with orthorexia nervosa
Authors: Vuillier Laura , Greville-Harris Maddy , Moseley Rachel Louise
Published: August 2024

Purpose
This study aimed to explore emotional functioning in individuals with varying levels of orthorexia nervosa (ON) symptoms. Given the established links between emotion dysregulation and other eating disorders (EDs), and the conceptualization of ON within the ED spectrum, this research sought to examine the relationships between ON symptomatology and emotion regulation strategies, alexithymia, and beliefs about emotions.
Methods
A large sample (N = 562) completed self-report measures with high psychometric properties, assessing ON traits (E-DOS), emotion regulation strategies (DERS-SF and ERQ), alexithymia (TAS-20), and beliefs about emotions (ERQ). The study used well-validated measures to address limitations of previous research.
Results
Individuals with high ON traits demonstrated difficulties in most aspects of emotional functioning compared to those with low ON traits. Suppression, but not reappraisal, partially mediated the relationship between beliefs about emotions and ON symptoms. Believing emotions are bad or useless, difficulty controlling impulses, and relying on suppression to regulate emotions were most strongly associated with ON symptoms.
Conclusion
This study provides evidence that emotion dysregulation plays an important role in ON symptomatology. The findings suggest that when emotions feel unhelpful or uncontrollable, and maladaptive strategies like suppression are employed, individuals may seek perceived control through pathologically 'healthy' eating. There is currently no diagnosis criteria for ON, and consequently no clear treatment pathway. Our research suggests that specific aspects of emotional functioning such as beliefs about the usefulness of emotions or difficulties with feeling out of control when upset may be a useful treatment target to help individuals with ON develop healthier coping mechanisms and reduce reliance on rigid dietary rules as a means of emotional regulation.
Level of evidence:
Level III: Evidence obtained from well-designed cohort or case-control analytic studies
Vascular Microphysiological System for Investigating Endothelial Barrier Function during Organ Preservation and Reperfusion
Authors: Kim Yongdeok , Goswami Ishan , Gill Elisabeth , Mahmoodi Seyed Reza , Consiglio Anthony N. , Velazquez Jazmin , Nieman Gabriel , Alburo Alexis Abigail A. , Woods Brady , Ellis Bradley W. , von Reiterdank Irina Filz , Uygun Korkut , Uygun Basak E. , Rubinsky Boris , Healy Kevin E.
Published: August 2024

Endothelial cell damage after cold preservation and reperfusion injury causes deterioration of the endothelial barrier and ultimately results in edema, leading to transplant failure. Here, we introduce a vascular microphysiological system (MPS) as a testbed to investigate the combinational effect of thermal and fluid perturbations (i.e., wall shear stress) on human endothelial barrier function. We compared two methods of organ storage: isochoric supercooling (ISC) preservation, which prevents ice formation at subzero temperatures; and, the standard clinical protocol of static cold storage (SCS) at 4 °C. Integrating electrical impedance measurements on chip allowed real-time monitoring and quantification of barrier function during preservation and reperfusion protocols. Isochoric supercooling preservation enabled longer periods of preservation with superior recovery of barrier function during reperfusion, and had lower metabolic activities compared to static cold storage. Genomic analysis revealed injury and recovery mechanisms at the molecular level for the different preservation and reperfusion conditions. The multifunctional vascular microphysiological system provided a physiologically relevant in vitro model recapitulating ischemia-reperfusion injury to the endothelium. The vascular MPS has potential for optimizing organ preservation protocols, ultimately improving organ transplant viability.
Unveiling the Barriers to Digital Transformation in Higher Education Institutions: A Systematic Literature Review
Authors: Si Amando Jr. Pimentel
Published: August 2024

This study investigates the challenges hindering the implementation of Digital Transformation (DT) in Higher Education Institutions (HEIs) by thoroughly reviewing the literature. It identifies multiple dimensions and subdimensions of these barriers to offer valuable insights to help HEIs navigate their transformation processes successfully. By doing so, they can effectively address the changing requirements of students and society in an increasingly digital environment. This study followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, synthesizing data from 20 relevant peer-reviewed articles published between 2019 and 2024. NVivo and Zotero were utilized as methodological instruments for coding, thematic analysis, and text mining to extract insights from the chosen articles to construct a Concept-centric Matrix on Barriers to Digital Transformation (DT) in Higher Education Institutions (HEIs). The result of this study is summarized in a Concept-centric Matrix on Barriers to DT in HEIs consisting of nine (9) dimensions such as (i) Digital Vision, Strategy, and Policies; (ii) Digital Leadership and Management; (iii) Digital Organization; (iv) Digital Resources; (v) Digital Competence; (vi) Digital Stakeholder Management; (vii) Digital Culture; (viii) Digital Academic; and (ix) Digital Ethics. Each dimension has subdimensions of barriers (n=80). Despite various sectors anticipating significant disruption from DT, many HEIs feel inadequately prepared to adapt because of the barriers to its implementation. The ongoing DT within HEIs reveals a complex landscape marked by various intertwined barriers that necessitate a strategic reevaluation and a commitment to fostering an inclusive, responsive educational environment.
Comparative Review of Single-Criteria and Multi-Criteria Optimisation Problems using Meta-heuristic Algorithms.
Authors: Okechukwu Cornelius , Silhavy Radek , Oyelere Solomon , Silhavy Petr
Published: August 2024

This paper explores using metaheuristic algorithms for single-criteria optimisation problems (SCOP) and multi-criteria optimisation problems (MCOP). It highlights the critical differences between these types, noting that SCOP focusses on a single objective while MCOP deals with conflicting goals. We applied metaheuristic algorithms inspired by natural phenomena to both problem types and provided a table comparing generic algorithms with problem-specific adaptations (PSAs), including their applications. A case study customised a contemporary algorithm for the Traveling Salesman Problem (TSP) using Genetic Algorithms (GA). At the same time, another examined the differences between generic algorithms and PSAs in a multi-criteria context with the Multi-Objective Knapsack Problem, utilising Multi-Objective Genetic Algorithms (MOGA) and Multi-Objective Particle Swarm Optimisation (MOPSO) alongside their tailored versions. The results indicate that PSAs outperform generic algorithms in SCOPs. The GA for TSP reduced the total journey distance over the generations, indicating progress towards optimal solutions. Similarly, in MCOP, tailored algorithms produced higher quality Pareto fronts, with better average hypervolume values and lower standard deviations than generic alternatives. We also discuss recent advancements and suggest future research directions for enhancing metaheuristic applications in optimisation.
Evaluating and Enhancing the Tourism Attraction of Phu Quoc Island: An Ecological Economic Approach Integrated with AI and Big Data Analytics
Authors: Ngo-Hoang Dai-Long
Published: August 2024

Phu Quoc Island, Vietnam's largest island, is celebrated for its stunning natural landscapes and rich cultural heritage. This study introduces an innovative approach to evaluating the factors contributing to Phu Quoc's tourism attraction by combining a modified gravitational model with ecological economic principles, Artificial Intelligence (AI), and Big Data analytics. By incorporating real-time data on biodiversity, carbon emissions, renewable energy usage, and tourist behavior, the study provides a comprehensive framework for promoting sustainable tourism on the island. The findings offer actionable insights and a strategic roadmap for enhancing Phu Quoc's appeal as a green and sustainable tourist destination, ensuring long-term economic and environmental benefits.
Single-molecule detection of transient dimerization of opioid receptors 2: Heterodimer blockage reduces morphine tolerance
Authors: Zhou Peng , Kasai Rinshi S. , Fujita Wakako , Tsunoyama Taka A. , Ueda Hiroshi , Pigolotti Simone , Fujiwara Takahiro K. , Kusumi Akihiro
Published: August 2024

Heterodimerization of opioid receptors (ORs), MOR, KOR, and DOR, is implied in their functional regulation and diversification, and thus its understanding is crucial for developing better analgesic treatments. However, our knowledge on OR heterodimerization/heterodimers remains limited. Here, using single-molecule imaging and functional analysis, we found that MOR, the main morphine receptor, repeatedly forms transient (≈250 ms) heterodimers with DOR every 1-10 seconds, but not with KOR, whereas DOR and KOR also form transient heterodimers. We obtained all the heterodimer-monomer equilibrium constants and rate constants with/without agonists. We identified the critical heterodimer binding sites in the extracellular domains, in addition to the less-specific transmembrane domains, and developed soluble peptide blockers for MOR-DOR and DOR-KOR heterodimerization, using amino-acid sequences mimicking the extracellular binding sites. With these peptide blockers, we dissected the monomer/dimer roles in OR internalization and signaling. The soluble MOR-DOR heterodimer blocker reduced the development of long-term morphine tolerance in mice.
Healthy Ageing in Malaysia by 2030: Needs, Challenges and Future Directions
Authors:   Head, Medical and Health Science Cluster, Majlis Profesor Negara, Selangor, Malaysia, Abdullah Jafri Malin ,   Department of Neurosciences and Brain Behaviour Cluster, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia, Ismail Amin ,   Deputy Head, Medical and Health Science Cluster, Majlis Profesor Negara, Selangor, Malaysia,   Department of Nutrition, Faculty Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia, Yusoff Muhamad Saiful Bahri ,   Secretary, Medical and Health Science Cluster, Majlis Profesor Negara, Selangor, Malaysia,   Department of Medical Education, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia,   Center for the Development of Academic Excellence, Universiti Sains Malaysia, Pulau Pinang, Malaysia
Published: August 2024

This Editorial addresses the critical need for developing a healthy ageing society in Malaysia by 2030. With the country’s elderly population projected to increase significantly, the article explores current challenges, including healthcare disparities, a shortage of geriatric specialists and malnutrition. It evaluates existing policies and highlights successful international and local initiatives, suggesting specific recommendations to improve healthcare infrastructure, healthy ageing support and technological integration. Emphasising the importance of engaging private sectors, non-governmental organisations (NGOs) and community groups, this Editorial calls for a collaborative approach to address the economic and cultural aspects of ageing. This comprehensive strategy aims to ensure a resilient, healthy and inclusive environment for Malaysia’s ageing population by 2030.
Evaluating the Reliability and Model Fit of the 13-Item and 10-Item Big Five Inventory (Malay Version) among Malaysian Firefighters
Authors:   Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Bandar Baru Nilai, Negeri Sembilan, Malaysia, Abdul Azis Huwaida , Rahman Zairina A. ,   Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Bandar Baru Nilai, Negeri Sembilan, Malaysia, Rashid Mohd Radzniwan A. ,   Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Bandar Baru Nilai, Negeri Sembilan, Malaysia, Baharom Nizam ,   Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Bandar Baru Nilai, Negeri Sembilan, Malaysia, Awang Hamidin ,   Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Bandar Baru Nilai, Negeri Sembilan, Malaysia, Mohammad Lukman Nur Hafizah ,   Planning and Research Division, Fire and Rescue Department of Malaysia, Negeri Sembilan, Malaysia
Published: August 2024

Background: Lengthy instruments for assessing personality traits may not be applicable in certain research settings. In situations where time is scarce, a briefer measurement is preferable. However, the reliability of a briefer measurement of the Big Five Inventory (BFI) among firefighters in Malaysia has not been reported. This study aimed to investigate the reliability and model fit of the Malay version of the BFI with 13 items (BFI-13) and 10 items (BFI-10) among Malaysian firefighters. Methods: A cross-sectional study using cluster sampling was conducted in a state in Malaysia. Each respondent completed BFI-10 and BFI-13 using an online survey with a 1-month interval between each response. Reliability testing was evaluated using internal consistency and a 2-week interval test-retest. The model fit of these two BFI questionnaires was evaluated via confirmatory factor analysis (CFA). Results: A total of 124 firefighters participated in the study, with a zero-dropout rate. The Malay version of BFI-13 exhibited higher reliability by displaying good internal consistency with Cronbach’s alpha of 0.919, 0.838, 0.871 and 0.896 for the domains conscientiousness, neuroticism, agreeableness and extraversion, respectively, and acceptable test-retest reliability with moderate to good intraclass correlation (0.588–0.806). The CFA model also indicated that BFI-13 has a better model fit (comparative fit index [CFI] = 0.993; Tucker-Lewis index [TLI] = 0.991; standardised root mean squared residual [SRMR] = 0.029; root mean square error of approximation [RMSEA] = 0.035). Conclusion: The Malay version of BFI-13 is reliable and applicable enough to be supplementarily used in surveys among Malaysian firefighters. By using a brief personality assessment, it will reduce the cognitive and emotional burden on respondents.
O ENSINO EM SAÚDE ATRAVÉS DAS REDES SOCIAIS: UM ESTUDO DE CASO SOBRE PLANTAS MEDICINAIS E FITOTERAPIA
Authors: Bittencourt Alexandre Horácio Couto , Oliveira Elisa Barbosa de
Published: August 2024

O ensino sobre Produtos naturais e Fitoterapia em muitas situações encontra dificuldade na difusão de informações científicas. O objetivo deste trabalho foi analisar as contribuições científicas, difundidas em redes sociais e seu papel na construção do conhecimento. Através de Buscas em bases de dados, foi elaborado uma página no Instagran, @fitoterapiaemcasa. As postagens foram realizadas a partir de publicações científicas. Os dados mostram que as interações foram favoráveis, com grande dispersão das informações no território brasileiro e até mesmo em países do Mercosul. As análises mostraram o potencial das redes sociais como difusoras do conhecimento científico de forma lúdica e acessível. Os resultados demonstraram que o potencial da rede social frente a difusão das informações científicas visando aumentar o conhecimento da população frente ao tema. Trabalhos futuros serão desenvolvidos visando a confirmação deste potencial de ensino
A CARGA ESTÁ EM DIA, MAS, E A SAÚDE MENTAL?
Authors: Teixeira da Silveira Alcione Januária , Silva Amora Kênia Aparecida , Da Silva Keylla Evelyn
Published: August 2024

O estudo em questão faz referência aos caminhoneiros, que tem uma rotina imprevisível, exigindo muito esforço e dedicação por parte desses trabalhadores, devido à jornada bastante exigente nas estradas. Esse quadro envolve tanto questões físicas quanto psicológicas. Esses profissionais, na maioria das vezes, estão expostos a vários fatores que resultam em danos à saúde. Os caminhoneiros vivem em um ciclo vicioso acarretando problemas básicos que colocam a saúde em risco resultando em obesidade, hipertensão e diabetes, doenças comuns causadas pelo sedentarismo e a má postura. O objetivo da pesquisa foi investigar a realidade vivida pelos caminhoneiros, tendo como foco os danos causados à saúde mental.
SAÚDE MENTAL DOS ESTUDANTES DE MEDICINA: CARACTERÍSTICAS INDIVIDUAIS, SOCIOECONÔMICAS E CONTEXTUAIS
Authors: Lima Jogiely Larissa Ferreira , Rabelo Paulo Wictor Lima , Machado Yuri de Castro
Published: August 2024

Transtornos mentais são muito comuns  em estudantes de medicina, sejam por fatores acadêmicos, individuais ou sociais que potencialmente geram esse adoecimento mental. Este artigo apresenta como objetivo analisar os fatores de risco para desenvolvimento de doença mental no estudante de medicina, bem como avaliar os métodos de prevenção e controle do adoecimento mental nesse grupo de estudantes. Trata-se de uma revisão integrativa da literatura, para realização das pesquisas foram utilizadas as bases de dados: PubMed, Science Direct e BVS/MEDLINE. O processo de triagem contou com os seguintes critérios de inclusão: artigos que respondessem à pergunta de pesquisa, em inglês e que foram publicados entre 2017 a 2022. Como resultado, foi obtido um total de 12 estudos. A prevalência mundial de ansiedade identificada nos estudantes de medicina está aumentando exponencialmente a cada ano, sendo a taxa de cerca de 33,8%, variando entre 29,2% a 38,7%, sendo considerada substancialmente maior do que quando comparada com a população geral que variou de 3% a 25% conforme as escalas de rastreio para ansiedade e depressão. A carga excessiva de trabalhos acadêmicos, com consequente privação de sono, o baixo nível socioeconômico, a exposição a mortes de pacientes e os professores abusivos foram identificados como prováveis razões para as altas taxas de ansiedade dos estudantes de medicina. Além disso, foi identificada uma taxa de aproximadamente 9,5% da síndrome de Burnout nos acadêmicos de medicina, sendo 50% associados a fatores pessoais, 42% relacionados ao trabalho/ estudos e 12% relacionados ao paciente.  O presente estudo reafirma a necessidade da aplicação dos métodos de prevenção e controle pelas instituições de ensino, a fim de reduzir as taxas de incidência dos transtornos mentais nos acadêmicos de medicina e gerar uma melhoria na qualidade de vida, no desempenho acadêmico, no profissionalismo e na empatia em relação aos pacientes.
A CONSTRUÇÃO DE UM MODELO INTERDISCIPLINAR PARA A PROMOÇÃO DA SAÚDE DO SERVIDOR PÚBLICO EM UMA UNIVERSIDADE FEDERAL
Authors: Carolina Meira Moser  , Gislaine Thompson Dos Santos  , Mariana Bello Porciuncula  , Mariana Valls Atz  , Milton Humberto Schanes Dos Santos  , Ana Carolina Brondani  , Rogério Miranda Barros  , Carine Gatto  , Djanir De Freitas Brião  , Glaci Rodrigues Leal  , Viviane Cordova Jardim Votto  , Viviane Fernandes Silveira Almeida  , Patrícia Costa Azevedo  , José Menna Oliveira  , Maria De Lourdes Giacomini
Published: August 2024

A promoção à saúde do servidor público federal objetiva melhorar processos de trabalho e ambientes organizacionais, mediante abordagens coletivas que influenciem ou modifiquem hábitos. O objeto deste trabalho é a trajetória da Divisão de Promoção da Saúde (DPS) da Universidade Federal do Rio Grande do Sul, que apresentou mudanças significativas em sua micropolítica de trabalho. Objetiva-se relatar a experiência das ações desenvolvidas pela DPS em sua atual configuração, mediante a descrição da transposição de uma lógica assistencial e fragmentada, para uma em que a saúde do servidor é entendida em uma dimensão ampla e integrada. A DPS resulta da união de um serviço de enfermagem, que atuava em ações de vacinação e procedimentos; e uma divisão de atenção psicossocial que acompanhava servidores com questões de saúde relacionadas ao trabalho. Posteriormente, uniram-se à equipe outros profissionais, mas o caráter individual dos processos de trabalho ainda era predominante. Com a pandemia da COVID-19, a equipe passou a realizar reuniões semanais, facilitando a adesão ao formato de teletrabalho e viabilizando a promoção de discussões sobre o papel do setor, o alcance das atividades e a divisão de tarefas. Esse contexto, aliado também à mudança de chefia,  permitiu a transformação do trabalho para um modelo mais democrático, colaborativo, dialógico e interdisciplinar. Nos últimos três anos, diversos trabalhos foram desenvolvidos: projetos de educação para saúde; atendimentos psicossociais e intervenções em equipes; ações de capacitação; materiais de divulgação, redes sociais e podcast; criação de Programa de Apoio a Gestantes, Lactantes e Adotantes; reconfiguração de Programa de Educação para Aposentadoria; e realização de Censo de Saúde. Observa-se que os atores envolvidos, frente às modificações institucionais causadas pela reestruturação organizacional e pela pandemia, potencializaram suas ações frente às adversidades, utilizando-se de momentos intercessores para o fomento de novos paradigmas.
SAÚDE AMBIENTAL NO AMBIENTE URBANO: A IMPORTÂNCIA DA ARBORIZAÇÃO E JARDINAGEM URBANA PARA O MEIO AMBIENTE E QUALIDADE DE VIDA DOS CIDADÃOS
Authors: Fontes Yago Magalhães
Published: August 2024

A arborização urbana é a atividade de cuidar e preservar jardins e áreas de lazer dotadas de formatos de flora têm também capacidade de apoio não somente estético, mas também para a qualidade de vida de um município quando empregada pelo poder público. Pois a jardinagem quando empregada pelo poder público foca em um direito constitucional de melhora da qualidade de vida e acesso à um ambiente saudável, mesmo quando empregada no meio urbano. Não é incomum presenciar atividades de revitalização de parques e praças ou plantio de diversas árvores ou arbustos nas grandes cidades como São Paulo ou Rio de Janeiro, essas atividades têm sido cada vez mais frequentes e têm ocorrido para garantir melhor qualidade de vida urbana através da arborização, mas é preciso se perguntar até onde esse formato de atividade pode ajudar a qualidade de vida ambiental do residente desses municípios urbanos e se essas atividades são suficientes para a vivência nesses espaços, e também qual o nível e de que forma a jardinagem em si é benéfica para o meio ambiente. Durante esse artigo são demonstrados os conceitos entorno da arborização e jardinagem, como a própria arborização urbana se desenvolve tanto como uma forma de apoio ao meio ambiente, como também uma atividade de função social, essas questões são trabalhadas nesse documento através de uma metodologia bibliográfica e documental, onde em um primeiro momento são apresentados os conceitos de arborização urbana, posteriormente será apresentado como a arborização urbana conversa com o direito de um meio ambiente saudável e por fim será analisada sua real capacidade de preservação e conservação ambiental e de qualidade de vida.
IDENTIFICAÇÃO DOS CAMPOS DE EXPERIÊNCIAS NA BASE NACIONAL COMUM CURRICULAR DA EDUCAÇÃO INFANTIL
Authors: De Fúcio Lidiane Hott , Maria Diniz Rondel Denízia , Almeida Mendes Andréia , Jacqueline Helen de Lima  , Moisés Luiz Gomes Siqueira  , Paulo Vinícius Silva de Santana
Published: August 2024

Trata-se de uma revisão bibliográfica pautada nos Campos de Experiência da Educação Infantil na Base Nacional Comum Curricular (BNCC). A referida base traz orientações curriculares nas mais diversas disciplinas, além de orientações para formação dos professores, criação de material didático e formas de avaliação. No caso da educação Infantil, a BNCC indica as experiências fundamentais para que as crianças de 0 a 5 anos aprendam e se desenvolvam por meio de campos de experiências que enfatizam noções, habilidades, valores e afeto. Assim, parte-se das seguintes indagações: como devem ser desenvolvidas as práticas da educação infantil tendo por base os campos de experiência? Quais as competências para cada idade? Como os objetivos propostos pela BNCC devem ser trabalhados em sala de aula?
A PARTICIPAÇÃO DA MULHER NOS ESTABELECIMENTOS AGROPECUÁRIOS: UMA ANÁLISE DO CASO DE MANHUAÇU COM BASE NO CENSO AGROPECUÁRIO 2017
Authors: Adriana Renata de Sousa  , Ana Louise Carvalho Fiúza  , Eliene de Sá Farias
Published: August 2024

A disparidade entre os gêneros é algo marcado na sociedade. Essa relação fica ainda mais discrepante quando se olha o meio rural das pequenas e médias cidades no interior do Brasil, um exemplo disso é Manhuaçu, cidade agrária e uma das maiores produtoras de café do Brasil. Dado esse panorama, o presente trabalho teve por objetivo analisar a participação da mulher na direção dos estabelecimentos agropecuários do município de Manhuaçu. Buscou-se, de forma específica, analisar a participação da mulher, considerando os diferentes modos de gestão do estabelecimento agropecuário, considerando a influência da “escolaridade” e da “idade” como fatores intervenientes nessa participação. Para isso, realizou-se uma estatística descritiva a partir dos dados do Censo Agropecuário de 2017. Com base nos dados analisados, percebe-se que Manhuaçu possui um cenário marcado pelo homem na tomada de decisões nos estabelecimentos rurais, resultado abaixo da média de Minas Gerais e do Brasil. Mesmo que as mulheres se capacitem mais, há problemas de sucessão familiar dentro do campo.
EDUCAÇÃO EM SAÚDE BUCAL PARA TRABALHADORES DE INDÚSTRIA ALIMENTÍCIA DE BISCOITOS: RELATO DE EXPERIÊNCIA EXTENSIONISTA
Authors: Silva Junior Manoelito Ferreira , Costa Clara Letícia Moreira , Silva Beatriz Xavier , Barreto Camila Souza , Lemos Camila Santos , Pimentel Eduarda Silva Meira , Silva Gabriel Barra , Abreu Júlia Flores
Published: August 2024

As principais doenças bucais são derivadas do biofilme microbiano, e por isso, o tipo de alimentação modula sua patogenicidade. Sendo assim, trabalhadores da indústria alimentícia, como de biscoitos, podem apresentar maior consumo de carboidratos fermentáveis, e por isso, apresentam maior risco das doenças bucais. O objetivo foi relatar uma ação extensionista de educação em saúde bucal para trabalhadores de uma indústria alimentícia de biscoitos. A ação extensionista do ‘Projeto Sorrir: Promoção de saúde bucal por ciclos de vida e grupos vulneráveis’ foi realizada com trabalhadores da empresa Biscoitos Bispo, em maio de 2023, na Associação de Padeiros, no município de Jequié/BA. A atividade foi planejada e executada por seis acadêmicos e um docente do curso de Odontologia da Universidade Estadual do Sudoeste da Bahia, Jequié/BA. A atividade proposta foi planejada em quatro momentos: 1) uso de recursos visuais para sensibilização / conceituação / exemplificação sobre importância do sorriso saudável, impacto do consumo frequente de carboidratos na saúde bucal e relação custo-efetividade da prevenção; 2)  dinâmica de mitos e verdades com oito assertivas para problematização dos principais itens de higiene bucal (dentifrício, escova, fio dental e enxaguante), doenças e agravos bucais (cárie dentária, doença periodontal e perda dentária); 3) momento tira-dúvidas; e, 4) demonstrações com macromodelos bucais e instrumentos de higienização bucal. A ação com duração de uma hora teve a participação de 16 pessoas, quinze homens e uma mulher, sendo a maioria adultos jovens. Os diferentes métodos educativos utilizados foram efetivos. O uso de imagens do impacto do sorriso trouxe maior atenção sobre o tema. A dinâmica de mitos e verdades mostrou o baixo conhecimento sobre os itens de higiene e agravos bucais. No momento tira-dúvidas, os participantes interagiram com experiências e assuntos ainda não contemplados, tais como: busca do serviço odontológico, dor de dente e dente siso. Por meio das demonstrações das técnicas de higiene bucal, identificou-se a baixa adesão do uso do fio dental, ou ainda, de movimentos ântero-posteriores incorretos na escovação dos dentes. Conclui-se que a ação demonstrou o impacto da saúde bucal no bem-estar e contribuiu para conscientizar os trabalhadores sobre a relevância do cuidado bucal e adoção de hábitos saudáveis. Ainda, a elaboração e execução da atividade educativa para os trabalhadores da indústria alimentícia, estimulou o pensamento crítico e reflexivo dos acadêmicos para atender as especificidades de um público-alvo pouco explorado e alcançado pelos serviços de saúde.
Islamic Economic Concepts To Form Community Welfare From The Perspective Of Ibnu Khaldun's Thinking
Authors: Nurcahyo Satria Avianda , Isnawati Setya Indah , Widagdo Teguh Harso , Rizal Achmad
Published: August 2024

Purpose - This research aims to review Ibn Khaldun's thoughts regarding social welfare, Ibn Khaldun revealed that Allah outlined economic activities as an inseparable part of the social responsibilities that exist in society, and their incompleteness could threaten the continuity of world life and human existence.Method - This research is using a type of normative research, applying a library approach and a conceptual approach.Result - The result of this research indicates Ibnu Khaldun stated that Allah established muamalah activities as an integral form of responsibility in community life. Non-fulfillment can threaten world life and human welfare. In formulating three basic reasons for engaging in economic activity, Ibnu Khaldun explains that this is not only about fulfilling personal life needs. Ibnu Khaldun believes that the price of a good or service is influenced by the dynamic interaction between demand and supply. This concept highlights the interrelated relationship between the forces of demand and supply in determining the value of a product or service.  Implication - This study It is hoped that there will be management and supervision of market prices by the state in the field, as suggested by Ibn Khaldun in his great work Muqadimmah.Originality - In the economic context, Ibnu Khaldun also highlighted the importance of government vigilance regarding the amount of money in circulation.
Dividend Discount Model Theory Implementation Based On Maqashid Shariah In Indonesia Shariah Stock Market
Authors: Lulukiyyah Masdaliyatul
Published: August 2024

Purpose - The purpose of this article is to explore how the use of the Dividend Discount Model (DDM) can be enriched by taking into account the principles of Maqashid Syariah and the economic thinking of Imam Al-Ghazali.Method - This research uses a literature review method with a qualitative descriptive approach. Data was obtained through a study of relevant literature with a focus on the Dividend Discount Model (DDM), the concept of Maqashid Syariah, and the economic thought of Imam Al-Ghazali.Result - The results of the analysis show that the integration of the Dividend Discount Model (DDM) with the Maqashid Syariah concept and Imam Al-Ghazali's economic thinking can provide a more holistic approach and in accordance with Islamic values in evaluating share value in the Islamic capital market. This approach emphasizes the importance of taking into account aspects of social and spiritual benefit, as well as contributing to inclusive and sustainable economic development.Implication - The implication of this research is that the use of the Dividend Discount Model (DDM) which is enriched with the Maqashid Syariah concept and Imam Al-Ghazali's economic thinking can help improve the performance of the Islamic capital market and strengthen compliance with Islamic principles in economic activities. This can have a positive impact on community welfare and sustainable economic development in Indonesia.Originality- The integration of the Dividend Discount Model (DDM) with the Maqashid Syariah concept and Imam Al-Ghazali's economic thinking is an innovation that can increase our understanding of the relationship between religious values and economic practices.
The Role of Redox Environment in Tumors
Authors: Wu Jiaping , Hu Liling , Liu Wei , Liu Xiaowen , Zheng Jun , Tan Xiao
Published: August 2024

Reactive Oxygen Species (ROS) and the redoxin system regulate the redox
environment. Thus, they mediate various physiological and pathological processes involved
in tumor occurrence and development by activating redox-sensitive genes and
regulating redox signaling pathways, including tumor cell proliferation, migration, invasion,
and various cell death types. Therefore, the mechanism underlying redox environment
regulation must be clarified to accurately target this mechanism and improve the effect
of tumor treatment. This review introduces redox-sensitive transcription factors and
their activated downstream signaling pathways, and the application of inhibitors targeting
related transcription factors in tumor therapy.
Incorporation of Coffee and Stevia Leaf Powder in Making Gambir Leaf Tea
Authors: Lidiasari Eka , Sipahutar Ruth Elferawi , Rahmawati Laila , Priyanto Gatot , Defira Citra , Syaiful Friska , Syafutri Merynda Indriyani , Santoso Budi
Published: August 2024

Background:

Gambier leaf tea contains antioxidant compounds, but its astringent taste
makes this tea less popular. The addition of coffee leaf powder and stevia not only reduces the astringent
taste of this tea but can also increase the content of antioxidant compounds.

Objective:

This research aimed to investigate the physical, chemical, functional, and organoleptic
properties of gambir leaf tea incorporated with coffee and stevia leaf powder.

Methods:

The investigation was carried out using a non-factorial, completely randomized design
with 5 treatments, each repeated 5 times. These treatments were developed based on different ratios
of gambir leaf formulations: coffee leaf powder:stevia leaf powder, namely F1= 100:0:0, F2=
95:1.5:3.5, F3= 90:3:7, F4= 85:4.5:10.5, and F5= 80:6:14.

Results:

The results indicated that gambir leaf tea has IC50 values, total phenols, pH, water content,
and ash content ranging from 36.57-54.25 ppm, 304.5-376 mgGAE/g, 5.46-5.68,
10.06-12.56%, and 2.06-2.61%, respectively.

Conclusion:

Gambir leaf tea incorporated with coffee and stevia leaf powder was found to contain
antioxidant compounds, while water and ash content fulfilled SNI standards. Organoleptically,
the color and aroma produced were well-received by the panelists.