bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Recycled Concrete Aggregate Utilization Ratio on Thermal Properties of Self-Cleaning Lightweight Concrete Facades
Authors: Beytekin Hatice Elif , Şahin Hatice Gizem , Mardani Ali
Published: July 2024

In today’s environment, where energy is desired to be used more efficiently, it has been understood that the interest in the use of lightweight concrete with superior performance in terms of thermal insulation properties has increased. On the other hand, it has been stated that construction waste increases rapidly, especially after severe earthquakes. In this context, encouraging the use of recycled concrete waste and efficient disposal of construction and demolition waste is of great importance for the European Green Deal. It is also known that pollutants such as COx and NOx stick to facades over time, causing environmental pollution and visual deterioration. It has been reported that materials with photocatalytic properties are used in lightweight concrete facade elements to prevent such problems. This study examines the effect of using recycled concrete aggregates on the thermal properties of self-cleaning lightweight concrete mixtures (SCLWC). For this purpose, an SCLWC containing 1% TiO2 and 100% pumice aggregate was prepared. By replacing pumice aggregate with recycled concrete aggregate at the rates of 15%, 25%, 35%, 45% and 50%, four different SCLWCs with self-cleaning properties were produced. High-temperature resistance, thermal conductivity performance, microstructure analysis and photocatalytic properties of the produced mixtures were examined. It has been understood that the unit volume weight loss of SCLWC mixtures exposed to high temperatures generally decreases due to the increase in the recycled concrete-aggregate substitution rate. However, it was determined that the loss of compressive strength increased with the increase in the amount of recycled concrete-aggregate replacement. Additionally, it was determined that the thermal-conductivity coefficient values of the mixtures decreased with the use of pumice. After SCLWC mixtures were exposed to 900 °C, small round-shaped crystals formed instead of C–S–H crystals.
From Compliance to Capability: On the Role of Data and Technology in Environment, Social, and Governance
Authors: Solaimani Sam
Published: July 2024

The importance of Environment, Social, and Governance (ESG) considerations for businesses has evolved from compliance to a strategic imperative. This shift is driven by increased investor scrutiny, reputation and brand value impact, talent attraction, innovation stimulation, community relations, and global regulatory requirements. At the same time, the ESG regulations and policies, related technological landscape, and market trends are continuously changing. It is, therefore no longer tenable for firms to stick to a minimalistic approach of ESG regulatory box-ticking ‘compliance’; instead, it is becoming increasingly critical to develop ESG ‘capabilities’ that help firms to seamlessly and proactively adapt themselves to the changing environment and even turning it into new (strategic) opportunities rather than reluctantly reacting to change, being operationally and organizationally overwhelmed, and disrupted, often with inadequate response and poor adoption as result. Many studies show that data and technology can be powerful enablers of such capability. The evidence is, however, unstructured and dispersed. In response, this study consolidates existing research and presents a comprehensive conceptual framework, bridging the fragmented landscape of ESG data and the technology literature. It offers practical guidance for firms, helping them lay holistic data and technology foundations for ESG and advance toward higher maturity levels in their ESG capability.
Spatial Evolution and Driving Factors of Ecological Well-Being Performance in the Yellow River Basin
Authors: Liu Ningyi , Wang Yongyu , Liu Sisi
Published: July 2024

Ecological well-being performance (EWP) is a key indicator of sustainable development and has garnered significant research attention. This study measures the overall and stage-by-stage efficiency of the urban agglomerations in the Yellow River Basin based on the ends–means framework of steady-state economics. This study then delves into the spatiotemporal transfer characteristics of EWP through Moran’s I, and spatial Markov chains. Additionally, this research investigates the factors influencing EWP using a random forest model. The findings indicate a notable enhancement in EWP in the urban agglomerations in the YRB from 2006 to 2021, showing clear spatial agglomeration patterns. The shift in EWP types displays a “path dependence” effect, with distinct evolutionary paths influenced by spatial lag effects. Ecological input emerges as a key internal driver of EWP, while urbanization and technological advancements are highlighted as significant external factors. Industrial agglomeration and industrial structure also contribute to improving EWP. The findings of this study help to clarify the spatial and temporal characteristics of ecological welfare performance and its driving mechanisms in the urban agglomerations of the Yellow River Basin. This is conducive to the achievement of high-quality urban transformation and regional green development, and it provides a reference for the construction of an ecological civilization.
Evaluation Method of Magnetic Field Stability for Robotic Arc Welding Based on Sample Entropy and Probability Distribution
Authors: Zhong Senming , Yao Ping , Wang Xiaojun
Published: July 2024

In this study, we analyzed the arc magnetic field to assess the stability of the arc welding process, particularly in robotic welding where direct measurement of welding current is challenging, such as under water. The characteristics of the magnetic field were evaluated based on low-frequency fluctuations and the symmetry of the signals. We used double-wire pulsed MIG welding for our experiments, employing Q235 steel with an 8.0 mm thickness as the material. Key parameters included an average voltage of 19.8 V, current of 120 A, and a wire feeding speed of 3.3 m/min. Our spectral analysis revealed significant correlations between welding stability and factors such as the direct current (DC) component and the peak power spectral density (PSD) frequency. To quantify this relationship, we introduced a novel approach using sample entropy and mix sample entropy (MSE) as new evaluation metrics. This method achieved a notable accuracy of 88%, demonstrating its effectiveness in assessing the stability of the robotic welding process.
Assessment of Psoas Muscle Index in Middle-Aged Type 2 Diabetes Patients: Impact of Insulin Therapy on Sarcopenia
Authors: Taskent Ismail , Ece Bunyamin , Aydin Sonay
Published: July 2024

Objective: Sarcopenia, characterized by progressive skeletal muscle loss, poses significant health risks, including physical impairment and mortality. The relationship between sarcopenia and insulin resistance suggests insulin therapy’s potential in preserving muscle mass, particularly in Type 2 diabetes mellitus (T2DM) patients. This study aims to evaluate the Psoas Muscle Index (PMI) via computed tomography (CT) in middle-aged T2DM patients on insulin therapy versus oral antidiabetic drugs (OAD) and controls. Methods: This retrospective study included 107 middle-aged T2DM patients undergoing non-contrast CT scans and 58 age-matched controls. CT images were analyzed to calculate PMI. Statistical analysis included Chi-square tests, independent samples t-tests, Mann–Whitney U tests, and correlation analyses. Results: Insulin-treated patients exhibited higher PMI than OAD users (p < 0.001), while OAD users had lower PMI than controls (p < 0.001). No significant difference was found between insulin-treated patients and controls (p = 0.616). Negative correlations were observed between T2DM duration/age and PMI across all groups, with a positive correlation between T2DM duration and BMI observed in the OAD group. Conclusions: Insulin therapy in T2DM patients, regardless of age or disease duration, positively impacts muscle mass, highlighting its potential in preserving muscular health and advocating for tailored treatment strategies in T2DM management.
Functional Analysis of GRSF1 in the Nuclear Export and Translation of Influenza A Virus mRNAs
Authors: Schmierer Jordana , Takimoto Toru
Published: July 2024

Influenza A viruses (IAV) utilize host proteins throughout their life cycle to infect and replicate in their hosts. We previously showed that host adaptive mutations in avian IAV PA help recruit host protein G-Rich RNA Sequence Binding Factor 1 (GRSF1) to the nucleoprotein (NP) 5’ untranslated region (UTR), leading to the enhanced nuclear export and translation of NP mRNA. In this study, we evaluated the impact of GRSF1 in the viral life cycle. We rescued and characterized a 2009 pH1N1 virus with a mutated GRSF1 binding site in the 5’ UTR of NP mRNA. Mutant viral growth was attenuated relative to pH1N1 wild-type (WT) in mammalian cells. We observed a specific reduction in the NP protein production and cytosolic accumulation of NP mRNAs, indicating a critical role of GRSF1 in the nuclear export of IAV NP mRNAs. Further, in vitro-transcribed mutated NP mRNA was translated less efficiently than WT NP mRNA in transfected cells. Together, these findings show that GRSF1 binding is important for both mRNA nuclear export and translation and affects overall IAV growth. Enhanced association of GRSF1 to NP mRNA by PA mutations leads to rapid virus growth, which could be a key process of mammalian host adaptation of IAV.
Drivers of Daily Water Level Fluctuation of Shallow Groundwater in the Inner Delta of the River Danube
Authors: Trásy Balázs , Magyar Norbert , Hatvani István Gábor , Garamhegyi Tamás , Kovács-Székely Ilona , Kovács József , Trásy-Havril Tímea
Published: July 2024

Groundwater flow systems are influenced by the changes in surface waters as well as climatic factors. These teleconnections significantly increase in cases of extreme weather conditions. To prepare and mitigate the effect of such phenomena, the background factors that create and influence natural processes must be recognized. In the present study, 94 shallow groundwater (SGW) wells’ water level time series were analyzed in the inner delta of the River Danube (Europe) the Szigetköz region to explore which factors contribute to the development of diurnal periodicity of SGW and what its drivers are. The relationship between surface meteorological processes and SGW dynamics in the Szigetköz region was investigated using hourly data from monitoring wells. Hourly water temperature data exhibited weak correlations with meteorological parameters. However, daily averaged data revealed stronger correlations, particularly between SGW levels and air temperature and potential evapotranspiration. Diurnal periodicity in SGW fluctuations correlated strongly with potential evapotranspiration. The study also demonstrated the role of capillary fringe dynamics in linking surface evapotranspiration with SGW fluctuations. Changes in groundwater levels, even small, can significantly affect soil moisture, vegetation, and ecosystem functioning, highlighting the sensitivity of the unsaturated zone to SGW fluctuations driven by surface processes.
Youth Gang Involvement and Long-Term Offending: An Examination into the Role of Psychopathic Traits
Authors: Joseph Justin J.
Published: July 2024

Most policies to combat gang criminal behavior are rooted in deterrence and punitive strategies. This is fueled by moral panic, a get tough on crime rhetoric, and a lack of understanding for the psychological factors that may influence this behavior. Further, the extant literature has consistently observed that gang membership is associated with increased criminal behavior. In an effort to promote and shift away from punitive approaches in response to gang delinquency, the current study investigates the role psychopathic traits have in violent and property offending, longitudinally, in a sample of gang-involved youth. The study implemented count mixed effect models to investigate the topic longitudinally in waves 3, 5, 7, 8, 9, 10, and 11, while controlling for other variables with violent and property offending frequency. The current study found that some psychopathic traits are associated with offending behavior, longitudinally, in gang members and youth with a history of gang involvement. The findings suggest that gang intervention strategies should include empirically supported programs for treating psychopathic traits in gang identified youth to reduce involvement in delinquent behavior. Further, practitioners, researchers, and policymakers should collaborate to develop more empirically supported strategies to reduce and prevent gang delinquent behavior from an empathetic lens.
Association of Symptoms and Collaborative Care Intervention with Systemic Inflammation Biomarkers in ESKD
Authors: Kallem Cramer J. , Alghwiri Alaa A. , Yabes Jonathan G. , Roumelioti Maria-Eleni , Erickson Sarah , Rollman Bruce L. , Weisbord Steven , Unruh Mark , Vodovotz Yoram , Jhamb Manisha , Steel Jennifer L.
Published: July 2024

Key Points

There were no associations between biomarkers and patient-reported pain, fatigue, and depression in a large ESKD cohort at baseline.

Compared with control, the Technology-Assisted stepped Collaborative Care intervention had a short-term impact on reducing inflammatory burden.

Treatment modified the association between changes in symptoms and in certain proinflammatory biomarkers (TNF-α and high sensitivity C-reactive protein) over time.

Background

Patient-reported symptoms are associated with inflammation biomarkers in many chronic diseases. We examined associations of inflammation biomarkers with pain, fatigue, and depression in patients with ESKD and the effects of a Technology-Assisted stepped Collaborative Care (TĀCcare) intervention on these biomarkers.

Methods

In the TĀCcare multisite randomized control trial, data on patient-reported symptoms were collected at baseline and 3 and 6 months. Anti-inflammatory (IL-1 receptor agonist, IL-10), proinflammatory (TNF-α, high sensitivity C-reactive protein, IL-6), and regulatory (IL-2) biomarkers were assayed. Linear mixed-effects modeling was used to examine within-group and between-group differences after adjusting for age, sex, race, and comorbidities.

Results

Among the 160 patients (mean age 58±14 years, 55% men, 52% white), there were no significant associations between inflammation biomarkers and pain, fatigue, or depression at baseline. Both intervention and control groups demonstrated reductions in IL-10 and IL-1 receptor agonist over 6 months (β range=−1.22 to −0.40, P range=<0.001–0.02) At 3 months, the treatment group exhibited decreases in TNF-α (β=−0.22, P < 0.001) and IL-2 (β=−0.71, P < 0.001), whereas the control group showed increases in IL-6/IL-10 ratio (β=0.33, P = 0.03). At 6 months, both groups exhibited decreases in IL-2 (β range=−0.66 to −0.57, P < 0.001); the control group showed significant increases in the ratio of IL-6/IL-10 (β=0.75, P < 0.001) and decrease in TNF-α (β=−0.16, P = 0.02). Compared with controls, the treatment group demonstrated significantly decreased IL-2 at 3 months (β=−0.53, P < 0.001). Significant interaction effects of treatment were observed on the association between changes in proinflammatory biomarkers (TNF-α and high sensitivity C-reactive protein) levels and changes in symptom scores from baseline to 6 months.

Conclusions

The TĀCcare intervention had a short-term impact on reducing inflammatory burden in patients with ESKD. More studies are needed to confirm our findings and to determine whether these biomarkers mediate the link between symptoms and disease progression.

Clinical Trial registration number:

ClinicalTrials.gov NCT03440853.
Potential role of gastro-intestinal microbiota in terrestrial snails
Authors: Idczak-Figiel Paulina A. , Nowakowska Anna
Published: July 2024

This review provides an overview of the potential impact of the intestinal microbiota of land snails on their survival and functioning in a constantly changing environment. The diverse communities of microorganisms that inhabit both the outside and inside of animals in unique ecosystems
help them to survive in constantly changing environmental conditions. A diverse microbial community is critical for digestion and nutrient delivery, but it is also important for animals that are adapting to new ecological niches. Molluscs are stable, multicellular in vivo systems that
can be used to study the symbiotic relationships between microorganisms and animals, as well as how microbes affect an animal???s physiology and ecology. Furthermore, because of the vast number of species and the ecological diversity of molluscs, they allow for a better understanding of the
variability of the microbiota associated with both their location in the host organism and the host in the environment. The microbiome is critical to a body’s homeostasis and survival in changing environmental conditions. This is true not only for terrestrial molluscs, but also for freshwater
and marine species, which use the properties of the microorganisms that inhabit them to counteract the effects of stress.
“Não(s) de cara” na Tentativa de Acesso à Laqueadura Tubária
Authors: Gonçalves Rodrigues Cristina , Peixoto Pinheiro Polyana , De Lima Sousa Vieira Roberta , Machado das Neves André Luiz , Coelho Prata Maria do Livramento , Therense Munique
Published: July 2024

O artigo analisa a experiência de mulheres sem filhos quanto ao acesso à laqueadura em Manaus/AM, Brasil. Trata-se de estudo netnográfico, com 20 participantes do grupo privado de uma rede social. A coleta de dados se deu por meio da publicação de roteiro com postagens temáticas, de 21 de junho a 13 de setembro de 2022, e posterior análise de conteúdo. A primeira categoria de resultados aborda as dificuldades quanto à realização da cirurgia, seus requisitos e o acesso informal ao conhecimento dos direitos sexuais e reprodutivos. A segunda, a invalidez do consentimento da mulher como característica principal do atendimento por profissionais de saúde. A terceira, o itinerário emocional imposto a quem busca a laqueadura. Conclui-se que o consentimento para realização da laqueadura tubária é invalidado por profissionais de saúde, que agem promovendo a refundação da Lei e atuando como representantes da biopolítica de Estado de controle dos processos reprodutivos.
Violencia, vulnerabilidad y víctima
Authors: Martínez María
Published: July 2024

Violencia, vulnerabilidad y víctima son parte del vocabulario de nuestra época. Y lo son particularmente en los feminismos que han abandonado o subsumido otros conceptos más propios: opresión, desigualdad, discriminación… Violencia, vulnerabilidad y víctima es un vocabulario particularmente fértil: produce sujetos pero, dados los significados que se les otorgan a esas categorías, también los desproducen. Sobre esta tensión trabaja este artículo. La propuesta que recorre el texto es que violencia, vulnerabilidad y víctima son categorías y mecanismos des-aparecedores: permiten existir en los marcos de existencia de la economía moral del humanitarismo, al tiempo que impiden ser part-entière de la esfera de aparición, que es la que constituye al sujeto-ciudadano, incluso lo humano. Sostengo esta propuesta a partir de trabajos de investigación de corte cualitativo en España con, además de expertas, mujeres víctimas de violencia de género y con trabajadoras sexuales.
What is life? Ethical and biopolicy considerations in the light of cinema
Authors: Gomes Valter , Gomes Gabriela , Motta Oswaldo Jesus Rodrigues da
Published: July 2024

For a better understanding of what life is, one can rescue Saint Augustine's notes for the time and still, with an opportunity in the arguments of the Bishop of Hippo, if this question really makes sense, once if we want to explain, I already demonstrate the lack of knowledge. Or, if there is really a need to reflect in ethical terms. This brief communication will start from the assumption that the question What is life? It is extremely problematic from an ethical point of view. As a starting point, the Aristotelian conjectures about the concept of life and the Foucauldian analysis of power relations in Western societies in the light of cinema will be approached. Will still be concepts such as biopower, biopolitics and (bio)ethics are presented.
Leucoencefalopatía Multifocal Progresiva causada por Virus JC
Authors: Lucero Paulette Analía Fajardo , Alencastro Jhon Alexander Ponce , Cejido Silvia Alexandra Aguabi , Guayacondo Diana Eugenia Saquicela , Guerrero Leonel Alexander Baños , Wong Teresa Layfon Jarrin
Published: July 2024

La leucoencefalopatía multifocal progresiva (LMP) es una enfermedad poco común y catastrófica que afecta la mielina, la capa protectora de los nervios en el cerebro, causando daño en la sustancia blanca cerebral. Esta enfermedad es ocasionada por el virus JC, un tipo de poliomavirus humano que generalmente se contrae durante la infancia y solo conduce a esta afección. La LMP es más frecuente en personas con sistemas inmunológicos debilitados, especialmente aquellos que son portadores del virus de la inmunodeficiencia humana (VIH). Las lesiones desmielinizantes provocan una variedad de síntomas neurológicos que requieren un diagnóstico preciso y confiable para distinguirla de otras condiciones.
Desenvolvimento de aplicativo para cirurgias endoscópicas com visualização direta em tempo real por meio de óculos 3D
Authors: Vargas Rogério Santos , Bringmann Deise Renata , Corso Leandro Luís
Published: July 2024

A cirurgia geral tem passado por uma transformação significativa ao longo do tempo, graças à introdução e aprimoramento das técnicas minimamente invasivas. Essas técnicas são notáveis por reduzirem a morbidade pós-operatória e acelerarem o processo de recuperação em comparação com as abordagens convencionais de cirurgia aberta. A endoscopia tem se destacado como uma das modalidades cirúrgicas mais proeminentes, representando uma técnica fundamental na medicina contemporânea. Ao fornecer uma visão interna do corpo, a endoscopia tem revolucionado a abordagem cirúrgica, contribuindo significativamente para os avanços na área médica.  Assim, este estudo tem como objetivo geral apresentar o desenvolvimento de um software para gerenciamento de cirurgias endoscópicas, que utiliza óculos 3D para visualização em tempo real. A proposta do software de gerenciamento é simplificar o processo cirúrgico, permitindo que os cirurgiões foquem diretamente na área cirúrgica enquanto visualizam a transmissão através dos óculos, evitando a necessidade de desviar a cabeça para um monitor. O processo de desenvolvimento do software passou por várias etapas, incluindo customização e testes piloto com médicos em diferentes locais. O sistema funciona com um capacete de realidade mista conectado a uma câmera óptica, permitindo que o cirurgião visualize o campo cirúrgico e o paciente através dos óculos. Além disso, o médico pode transmitir o procedimento para outros médicos através da internet. A adoção dessa tecnologia pode reduzir o tempo de internação e os custos, além de facilitar a cirurgia com maior precisão e favorecer uma melhor postura ergonômica. Essa tecnologia também tem potencial para ser utilizada em aulas e cirurgias com acompanhamento remoto em tempo real.
Avaliação da relação entre obesidade e a depressão na infância e juventude
Authors: Souza Fernanda Goulart Nunes de , Oliveira Marília Souza Bueno de , Marcon Maria Júlia Barco , Lima Ana Paula , Guilhen Gilmar Ledo , Morais Gabriela Rodrigues Silva de , Pascale Karina , Barboni Letícia de Jesus Dias , Bignardi Beatriz , Nenartavis Ana Claudia Martins , Jesus Tainah Marques de , Bonamin Natielly Luiza , Vasconcellos Cesar Augusto Galvao Banhatto
Published: July 2024

INTRODUÇÃO: A obesidade é uma doença crônica causada pelo aumento do aporte calórico com aumento do tecido adiposo. A etiologia da doença é multifatorial e aflige a população de maneira global, inclusive a faixa etária infantil. Nessa idade, o aumento de peso interfere na interpretação corporal, o que influencia no desenvolvimento de doenças como a depressão. OBJETIVOS: Avaliar a relação entre a obesidade e a depressão infantil, avaliando a existência de fatores de risco associados.  METODOLOGIA: Trata-se de uma revisão integrativa na base de dados PUBMED utilizando os descritores “OBESITY AND DEPRESSION AND CHILD’’ para artigos publicados entre 2019 e 2024. RESULTADOS: Um estudo de meta-análise demonstrou que a prevalência da obesidade entre crianças de até 14 anos é de 15,5%, dentre elas 10,4% apresentam depressão, um número alto quando comparado ao de crianças não obesas que é de 5%. A obesidade grave é comum em crianças que possuem depressão (26,8%), transtornos de ansiedade (18,4%) e transtornos alimentares (37,4%). O sexo feminino apresenta significativamente mais chances de desenvolver depressão quando comparado ao sexo masculino. Além disso, é importante analisar a autoimagem e a autoestima dessas crianças, uma vez que estudos demonstram que a insatisfação corporal é um importante fator de risco para a depressão. Os exercícios físicos são uma boa alternativa de tratamento para crianças afetadas com obesidade e depressão. CONCLUSÃO: A obesidade e a depressão estão associadas de maneira significativa, dando destaque às crianças do sexo feminino que apresentaram maiores chances de desenvolver depressão. Quanto ao tratamento, a atividade física, seguida pelas atividades em grupo, demonstraram resultados significativos no tratamento tanto da depressão, quanto da obesidade.
Cintilografia de perfusão do miocárdio: uma ferramenta essencial na avaliação de Síndrome Coronariana
Authors: Soares Jayane Paula Carneiro , Machado Bruno Gonçalves , Paula Daniel Carvalho de , Alves Pedro Henrique Fabris , Pacheco Lara Varela Bastos
Published: July 2024

A cintilografia de perfusão do miocárdio (CPM) é útil para detectar o grau e a localização do defeito de perfusão miocárdica, pois auxilia no manejo clínico de doença arterial coronariana (DAC). Tal ato permite uma avaliação mais específica para pacientes que sofrem de alguma síndrome coronariana aguda (SCA), haja visto que está diretamente relacionado à permeabilidade das artérias coronarianas e sua obstrução. Objetivo: Investigar, interpretar e revisar os achados sobre Cintilografia de Perfusão do Miocárdio (CPM), relacionando a validade do exame em pacientes com Síndrome Coronariana Aguda. Metodologia: Utilizou-se a base Medical Literature Analysis and Retrieval System Online (MEDLINE/PubMed), sob os descritores Cintilografia miocárdica; Síndrome Coronariana Aguda, com seleção de artigos de revisão e artigos originais, seguindo critérios de elegibilidade. Foram encontrados 518 textos, com seleção inicial de 107, dos quais restaram 48 artigos elegíveis. Resultados: Os artigos redigidos em língua inglesa contemplavam também publicações de autores e periódicos de diferentes nacionalidades. A maioria dos artigos abrangiam os anos de 2020 (14). Considerações finais: O uso da CPM é uma alternativa promissora para a terapêutica do manejo de SCA, pois estima auxilia no diagnóstico e estratificação de risco, principalmente em pacientes com SCA sem supradesnivelamento do segmento ST. Ademais, pacientes com dor torácica típica que procuram o pronto socorro para o alívio de sua dor tem possibilidade de avaliar a possibilidade de alguma DAC com esse exame, assim com melhor identificação da etiologia da sua dor, conseguirá um acompanhamento mais eficaz para evitar piores desfechos da doença.
Tríade da mulher atleta: uma revisão integrativa da literatura
Authors: Alves Lobo Isabella Garonce , Yamashiro Júlia Naomi , Anéas Fabrício Leal Albiero , Abduch Otávio Galvão Freire , Silve Larissa Raquel Correia de Almeida Souza , Leite Letícia Costa , Alves Lobo Pedro Giovanni Garonce , Moraes Rodrigo dos Santos
Published: July 2024

baixa densidade mineral óssea e disfunções no ciclo menstrual, podendo afetar diversos sistemas do organismo. Esta síndrome atinge principalmente mulheres atletas de esportes em que há cobranças estéticas, estando relacionada a um desequilíbrio entre ingestão calórica e demanda metabólica. Foi realizada uma busca a partir da base de dados PubMed® um levantamento de 22 artigos. Após aplicação dos critérios de inclusão e exclusão e posterior análise, obteve-se 6 estudos compreendidos nesta revisão integrativa. Atualmente, há questionários para identificar o risco de desenvolvimento de TMA, além de marcadores sensíveis para tais alterações. O manejo da paciente portadora de TMA baseia-se em um dieta adequada contendo nutrientes fundamentais para a função metabólica, saúde celular e prevenção de doenças, além de adequação da atividade física respeitando os limites do corpo, a fim de evitar microfraturas ósseas. A TMA pode afetar não só o percurso esportivo, mas o cotidiano da mulher caso não seja tratada corretamente. Dessa forma, é essencial que os profissionais de saúde sejam capazes de identificar um caso de TMA, a fim de tratá-la e evitá-la. A presente revisão integrativa objetiva elucidar os mecanismos e avanços recentes sobre a TMA, além de conscientizar os profissionais da área da saúde sobre o tema.
Perfil epidemiológico dos óbitos por neoplasia de estômago no estado de Alagoas no período de 2018 a 2022
Authors: Andrade Pedro Nogueira de , Ribeiro Maria Victoria de Morais Born , Alves Darah Yasmim Moreira , Silva Adolfho César Ferreira da , Aquino Ana Paula Souza de , Queiroz Mariana Lucena da Silva , Gomes Victória de Amorim Barros , Sá Neto Helion Lisboa de , Bezerra Evelyn Genielly Camilo , Barbosa Isadora Murta , Cândido Maria Clara dos Santos , Silva Ana Beatriz Bezerra , Albuquerque Juliana Guerra dos Reis Cavalcanti de
Published: July 2024

Introdução: No Brasil, o câncer de estômago ocupa a terceira posição em prevalência entre os homens e a quinta entre as mulheres. Objetivo: Objetivou-se com o estudo caracterizar o perfil epidemiológico da mortalidade por câncer gástrico no estado de Alagoas no período de 2018 a 2022.  Metodologia: Este estudo retrospectivo envolveu a coleta de dados da base DATASUS (Departamento de Informática do SUS), especificamente do Sistema de Informação de Mortalidade (SIM), A pesquisa focalizou indivíduos diagnosticados com a referida patologia durante o período estabelecido. As variáveis analisadas incluem ano de diagnóstico e notificação, sexo biológico, etnia, faixa etária, escolaridade e categoria de exposição. Resultados: No período de 2018 a 2022, houve um total de 662 óbitos por neoplasia de estômago em Alagoas, observou-se que a maioria adultos na faixa etária de 60 a 69 anos (26,58%), a maioria se revelou casado com 38,8%. Conclusão: Apesar de uma redução na incidência e mudanças no perfil epidemiológico, as neoplasias gástricas ainda são um grave problema de saúde pública devido à alta taxa de morbimortalidade. Portanto, é crucial direcionar pesquisas para essa área, pois há poucos estudos sobre o perfil epidemiológico do câncer gástrico na literatura brasileira.
Development and Test Application of Guidelines for Evaluating the Usability of Artificial Foot Products
Authors: Jung Sungbae , Yuk Sunwoo , Choi Ki-Won , Park Sangsoo ,   Society for Standards, Certification and Safety
Published: July 2024

Artificial foot is an assistive device worn by calf or thigh amputees to enable walking. Orthotic prosthesis including artificial foot are internationally classified as medical devices, but in Korea, they are still classified as assistive devices for the disabled rather than medical devices. All medical devices under the the Ministry of Food and Drug Safety regulation are required to conform to the international standard IEC 62366-1 since 2021. However, prosthetic orthotic products such as artificial foot are not classified as medical devices, so their usability test requirement has not yet been mandated. In this study, four prosthetic orthosis experts formed an advisory committee and applied IEC 62366-1, an international standard for medical device usability evaluation, to develop the usage scenarios for artificial foot products, in indoor and outdoor environments. After selecting 16 tasks in usage environments, we developed guidelines consisting of 52 questionnaires to determine the product's usability, including safety, effectiveness, and satisfaction. Three lower-leg amputees participated in the test application and responded to the survey of the guidelines for a prosthetic foot product while performing 16 tasks. this product received an average score of 3.42 out of 5, and the usability evaluation score was lower on unpaved roads and slippery tiles than on flat surfaces. It is expected that the experience in developing user suitability evaluation guidelines for artificial feet developed in this study can be usefully applied to the development of usability evaluation guidelines for other prosthetic and orthotic products.
Testing Framework of Polyimide-Based High Temperature Resistant Composite Materials for Aerospace Applications
Authors: Lee Joon Hyuk ,   Society for Standards, Certification and Safety
Published: July 2024

기 정립되어 있는 KS, ASTM, MIL 등의 시험규격은 일반적인 조건에서의 고분자섬유복합재 시험방법을 제시하고 있다. 본 연구에서는 대기권 이상의 환경조건에서 폴리이미드 기반 고분자섬유복합재가 경험할 수 있는 열특성 및 기계적 강도 파라미터를 포괄하는 특화 시험방법을 정리 및 제안하였다. 각각의 시험방법은 본소에서 특수기능용 고분자섬유복합재를 대상으로 다양한 환경조건 하 수행된 시험들을 거치며 정립되었다. 장비기반 시험방법 이외에도 본소에서 시험의 보조적 검증수단으로 점차 활용폭이 커지고 있는 복합재 내 열 전달 분석과 같은 컴퓨터 모델링의 예시를 소개하였다. 본 연구가 유관 시험, 공공 및 연구기관에서 우주항공용 폴리이미드 기반 고온섬유복합재 시험방법 연구동향 분석에 도움이 되길 기대한다.
Gestão estratégica como um diferencial competitivo a partir da Escola Cultural: o caso de sucesso de uma empresa gaúcha
Authors: Dos Santos Leandro Dorneles , Polacinski Edio , Souza João Artur de
Published: July 2024

A correta definição de estratégias organizacionais, atualmente, é considerada um diferencial competitivo para as empresas que buscam se tornar referência em seu segmento de atuação. As diretrizes, bem como as premisas e pressupostos que norteiam o desenvolvimento dessas, são detalhadas, discutidas e classificadas como as dez escolas do pensamento estratégico propostas por Mintzberg, Ahlstrand e Lampel, gurus da fascinante arte de definir estratégias para aumentar a competitividade. Assim, neste contexto, objetivou-se com este artigo, apresentar a escola cultural, uma das dez escolas do pensamento estratégico, como um diferencial estratégico de uma empresa PET. Para tanto, definiu-se como metodologia de pesquisa o estudo de caso, uma vez que o estudo é desenvolvido em uma empresa gaúcha, localizada no município de Santo Ângelo-RS, Brasil. Como principais resultados de pesquisa, destaque-se que a empresa analisada apresenta traços evidentes da escola cultural, contudo, como base para seu planejamento e definição de estratégias organizacionais, não envolve sua equipe de colaboradores nesta tarefa. Ressalte-se ainda, que além de indicar uma maior participação dos colaboradores no proceso de definição de estratégias organizacionais, outras sugestões são descritas com base na análise das informações coletadas na empresa pesquisada.
Impacto de intoxicación por ciguatera en Cuba
Authors: Arencibia-Carballo Gustavo , Granja Dayana Dellundé , Milanés Annia Martínez , Pérez Raúl González , Hernández Edna Alexandra Canto , Hernández Lizeth Ileana Canto , Castro Julio Antonio Sandoval
Published: July 2024

El presente trabajo se propuso estimar los costos de la atención médica a pacientes ingresados en el sistema de salud nacional de Cuba por la intoxicación alimentaria de ciguatera. Se realizó una exhaustiva revisión de los costos que implicaban estos ingresos que garantizan la calidad de los servicios al paciente y su atención durante el período promedio para llegar al cálculo de estimación por día. Se estima por primera vez en Cuba el costo promedio por día, el cual es de $1831.91 CUP (asumiendo costos diarios homogéneos sin complicaciones del paciente) y el costo para 3 días de ingreso 5495.73CUP, siempre considerando a pacientes sin complicaciones de salud, y un ingreso promedio es de 3 días. Se considera que los costos en la atención médica a estos pacientes son representativos y están acorde a la información procesada, pero que deben en el futuro ajustarse según los adelantos en sistemas de tratamientos médicos y cambios en los costos a partir del perfeccionamiento monetario del país, aunque la metodología utilizada permite un acercamiento a datos reales de utilización y manejo de la enfermedad, para establecer estrategias acorde a una visión más actualizada del impacto de la misma desde el punto de vista económico. La alta variabilidad en las condiciones por unidad hospitalaria a pesar de ser un sistema único nacional de atención médica sugiere continuar con estas estimaciones en el futuro para lograr una evaluación de mayor precisión.
Overview of the ornamental aquatic organisms market in Brazil
Authors: Mota Juliana Barros da , Pires Dara Cristina , Hoyos Daniela Chemin de Melo , Miranda-Filho Kleber Campos
Published: July 2024

This study aims to analyze the ornamental aquatic organisms market and identify key consumer obstacles in aquarium farming. A questionnaire comprising 57 questions was distributed via Virtual Social Networks (RSV), using the Snowball method during June and July 2023. The survey encompassed all 26 states and the Federal District. Data analysis relied on descriptive statistics. Out of 270 respondents, 65% were female, 34% were male, 0.4% identified as trans women, and 0.4% as trans men. Predominant states in the research included Minas Gerais (35.6%) and Amapá (20.4%). Regarding pet ownership, only 13% of consumers raise fish, behind the raising of dogs (56%) and cats (22%). Among the fish, 47% are small species, such as guppy, swordfish, betta, platy, and others. Reasons for discontinuing ornamental aquatic animal ownership included lack of time, insufficient information on care, pet mortality, and disease-related losses. However, 72% expressed continued interest in restarting. While the production of ornamental aquatic organisms has been on the rise, especially nationally, lack of information remains a primary barrier to increased adoption in Brazil. Therefore, expanding publicity, particularly through specialized aquarium stores, offers a viable solution to reducing mortality rates among aquarium animals and fostering consumer interest.
Tecnologias da raça Santa Inês: uma revisão
Authors: Oliveira Júlia Paiva de , Rosso Marcelo Augusto , Silva Marcelo Dourado da , Almeida Muryllo Silva , Oliveira Pedro Henrique de Souza , Barbosa Emanuela Nataly Ribeiro
Published: July 2024

A ovinocultura representa uma parcela significativa do setor alimentício e econômico, no Brasil e no mundo, sendo que nacionalmente a raça Santa Inês emerge como uma raça de grande relevância para produção de carne. Desta forma, este estudo tem por objetivo realizar uma revisão de literatura sobre as principais tecnologias da raça Santa Inês, com ênfase em suas características raciais e produtivas, bem como o seu processo de formação. A ovinocultura de corte no Brasil tem crescido, com a raça Santa Inês se destacando devido à sua adaptabilidade e precocidade. Sua formação envolve o cruzamento de diferentes raças, resultando em animais adaptados ao clima tropical. A raça apresenta características fenotípicas atrativas, como tamanho corporal e habilidade reprodutiva. Além disso, é adaptada a ambientes quentes e semiáridos, sendo economicamente viável em sistemas de confinamento. As características produtivas da raça incluem qualidade de carne, rendimento de carcaça e eficiência de produção, tornando-a uma opção interessante para a pecuária nacional. Observa-se, portanto, que a raça Santa Inês desempenha um papel importante na pecuária brasileira devido às suas características adaptativas e produtivas. No entanto, a seleção genética e o manejo adequado são essenciais para maximizar seu potencial produtivo e garantir a sustentabilidade das criações.
Intra-Operative Diagnostic Methods of Blood Flow and Control of Microsurgical Clipping of Cerebral Aneurysms: A Literature Review
Authors: Ахремчук А.И. , Сидорович Р.Р. , Змачинская О.Л.
Published: July 2024

Вмешательства на сосудах головного мозга относятся к одному из наиболее технически сложных разделов современной нейрохирургии. Осложнения, возникающие при клипировании аневризм сосудов головного мозга, к которым относят неполное выключение аневризмы из кровотока, компрессию клипсом афферентных, эфферентных и перфорирующих артерий, являются актуальной проблемой в хирургии церебральных артериальных аневризм (АА). Для профилактики осложнений, возникающих при клипировании аневризм, широко применяют следующие методы интраоперационной оценки кровотока, контроля клипирования: контактную ультразвуковую доплерографию, интраоперационную флуоресцентную видеоангиографию (ИФВА), ультразвуковую флоуметрию и нейроэндоскопию. Ультразвуковая контактная доплерография – это высокоинформативный метод ультразвуковой диагностики патологии сосудов, основанный на использовании эффекта Доплера. Интраоперационная флуоресцентная видеоангиография – метод, основанный на использовании флуоресцирующего красителя – индоцианина зеленого. Ультразвуковая флоуметрия – метод измерения объемной скорости церебрального кровотока. Нейроэндоскопия – эффективный метод в профилактике осложнений, возникающих при клипировании аневризм, использующий видеоэндоскопическую стойку, набор эндоскопов с различными углами обзора. В данном обзоре представлены данные методы с описанием их возможностей, преимуществ и ограничений, а также описаны приоритеты использования того или иного метода в зависимости от локализации аневризм сосудов головного мозга.

Interventions on cerebral vessels belong to one of the most technically complex sections of modern neurosurgery. Complications arising during clipping of cerebral aneurysms, which include incomplete disconnection of the aneurysm from the blood flow, compression of afferent, efferent and perforating arteries by clips, are an urgent problem in the surgery of cerebral arterial aneurysms. To prevent complications arising during clipping of aneurysms, the following methods of intraoperative blood flow assessment and clipping control are widely used: contact ultrasound Dopplerography, intraoperative fluorescent videoangiography, ultrasound flowmetry and neuroendoscopy. Ultrasound contact Doppler ultrasonography is a highly informative method of ultrasound diagnosis of vascular pathology based on the Doppler effect. Intraoperative fluorescence video angiography – a method based on the use of fluorescent dye indocyanine green. Ultrasound flowmetry – a method of measuring the volumetric velocity of cerebral blood flow. Neuroendoscopy is an effective method in the prevention of complications arising during aneurysm clipping, using a video endoscopy stand, a set of endoscopes with different angles of view. This review presents these methods with a description of their capabilities, advantages and limitations, and also describes the priorities of using one or another method depending on the localization of cerebral aneurysms.
Vestibular Migraine: Current Understanding of the Problem and Future Directions for Research
Authors: Марьенко И.П. , Ануфриева Е.В.
Published: July 2024

Вестибулярная мигрень может встречаться с частотой до 2,7% населения. Вестибулярная мигрень характеризуется повторяющимися вестибулярными симптомами, характерным анамнезом заболевания, подтверждающими связь головокружения с симптомами мигрени при исключении других причин вестибулярных симптомов. Представлены диагностические критерии вестибулярной мигрени Комитета по классификации вестибулярных расстройств Общества Барани и Комитета по классификации мигрени Международного общества головной боли (2018), а также особенности вестибулярной мигрени и вероятной вестибулярной мигрени. В статье приведена дифференциальная диагностика вестибулярной мигрени с другими заболеваниями со схожими клиническими проявлениями. Рассмотрены вопросы нейрофункционального тестирования при постановке диагноза «вестибулярная мигрень».

Vestibular migraine may occur in up to 2.7% of the population. Vestibular migraine is characterized by recurrent vestibular symptoms, a characteristic history of the disease, confirming the association of vertigo with migraine symptoms when other causes of vestibular symptoms are excluded. This article presents diagnostic criteria for vestibular migraine, formulated by the Committee for Classification of Vestibular Disorders of the Bárány Society and the Migraine Classification Subcommittee of the International Headache Society (HIS), 2018, and the features of vestibular migraine and probable vestibular migraine are presented. The differential diagnosis of vestibular migraine with other diseases with similar clinical manifestations is analyses in the article. The issues of neurofunctional testing in the diagnosis of vestibular migraine are considered.
Hereditary Neuromuscular Disease, Probably Caused by a Mutation in the TUBA4A Gene c.1049G>T (p. Gly350Val): Own Clinical Observation
Authors: Рушкевич Ю.Н. , Мальгина Е.В. , Лихачев С.А. , Петрович И.А.
Published: July 2024

В настоящем исследовании представлено описание собственного клинического случая наследственного нервно-мышечного заболевания, вероятно обусловленного мутацией в гене TUBA4A. Данный ген повсеместно экспрессируется в тканях человека, наиболее высокая экспрессия наблюдается в головном мозге. Преобладающим фенотипом у носителей мутации TUBA4A является боковой амиотрофический склероз, однако в нескольких случаях у пациентов была диагностирована врожденная миопатия, лобно-височная деменция, нигропатия с паркинсонизмом. Выявленная у пациентки патогенная мутация в гене TUBA4A является de novo и характерна для семейной болезни двигательного неврона. Однако в нашем случае отсутствуют на момент наблюдения признаки поражения мотонейрона как клинически, так и нейрофизиологически. Требуется динамическое наблюдение пациентки и в дальнейшем рекомендовано молекулярно-генетическое дообследование, а именно выполнение полного секвенирования экзома или генома. Медико-генетическое исследование имеет важное значение для понимания сложных патогенетических механизмов болезни двигательного неврона, ведущих к дегенерации двигательных нейронов.

In this study, we present a description of our own clinical case of a hereditary neuromuscular disease, probably caused by a mutation in the TUBA4A gene. This gene is ubiquitously expressed in human tissues, with the highest expression observed in the brain. The predominant phenotype in carriers of the TUBA4A mutation is ALS, but in several cases patients were diagnosed with congenital myopathy, frontotemporal dementia, and nigropathy with parkinsonism. The pathogenic mutation in the TUBA4A gene identified in the patient is de novo and is characteristic of familial ALS. However, in our case, at the time of observation, there were no signs of motor neuron damage, either clinically or neurophysiologically. Dynamic observation of the patient is required and further molecular genetic examination is recommended, namely, complete exome or genome sequencing. Medical genetic research is important for understanding the complex pathogenetic mechanisms of motor neuron disease leading to motor neuron degeneration.
Leptomeningeal Carcinomatosis
Authors: Рушкевич Ю.Н. , Павловская Т.С. , Стреха М.А. , Гвищ Т.Г. , Клюнчик С.Г. , Антоненко Д.А.
Published: July 2024

Лептоменингеальный канцероматоз, или канцероматоз мозговых оболочек, – это состояние, при котором поражаются оболочки головного и/или спинного мозга метастазами раковой опухоли. Первичным очагом могут являться опухоли различной локализации: легких, желудочно-кишечного тракта, молочной железы, меланома и др. Клинические проявления заболевания неспецифичны, решающее значение в постановке диагноза имеет выполнение МРТ головного и спинного мозга с контрастным усилением.

Leptomeningeal carcinomatosis or carcinomatosis of the meninges is a condition in which the membranes of the brain and/or spinal cord are affected by metastases of a cancerous tumor. The primary focus may be tumors of various localization: lung, gastrointestinal tract, breast, melanoma, etc. The clinical manifestations of the disease are nonspecific, and performing MRI of the brain and spinal cord with contrast enhancement is crucial in making a diagnosis.