bluuebunny/crossref_metadata_2025 huggingface dataset:
A Recombinant Turkey Herpesvirus Expressing F and HN Genes of Avian Avulavirus-1 (AAvV-1) Genotype VI Confers Cross-Protection against Challenge with Virulent AAvV-1 Genotypes IV and VII in Chickens
Authors: Śmietanka Krzysztof , Tyborowska Jolanta , Olszewska-Tomczyk Monika , Domańska-Blicharz Katarzyna , Minta Zenon , Rabalski Lukasz , Czarnota Anna , Kucharczyk Krzysztof , Szewczyk Boguslaw
Published: August 2019

Newcastle disease (ND) is responsible for significant economic losses in the poultry industry. The disease is caused by virulent strains of Avian avulavirus 1 (AAvV-1), a species within the family Paramyxoviridae. We developed a recombinant construct based on the herpesvirus of turkeys (HVT) as a vector expressing two genes: F and HN (HVT-NDV-F-HN) derived from the AAvV-1 genotype VI (“pigeon variant” of AAvV-1). This recombinant viral vaccine candidate was used to subcutaneously immunize one group of specific pathogen-free (SPF) chickens and two groups of broiler chickens (20 one-day-old birds/group). Humoral immune response was evaluated by hemagglutination-inhibition test and enzyme-linked immunosorbent assay (ELISA). The efficacy of the immunization was assessed in two separate challenge studies performed at 6 weeks of age with the use of virulent AAvV-1 strains representing heterologous genotypes IV and VII. The developed vaccine candidate elicited complete protection in SPF chickens since none of the birds became sick or died during the 2-week observation period. In the broiler groups, 90% and 100% clinical protection were achieved after challenges with AAvV-1 of IV and VII genotypes, respectively. We found no obvious relationship between antibody levels and protection assessed in broilers in the challenge study. The developed recombinant HVT-NDV-F-HN construct containing genes from a genotype VI AAvV-1 offers promising results as a potential vaccine candidate against ND in chickens.
Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution
Authors: Petrenko Valery A. , Gillespie James W. , Xu Hai , O’Dell Tiffany , De Plano Laura M.
Published: August 2019

Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using traditional principles of affinity selection, are substituted for phage proteins discovered through combinatorial avidity selection. Here, we substantiate the potential of combinatorial avidity selection using landscape phage in the discovery of Short Linear Motifs (SLiMs) and their partner domains. We proved an algorithm for analysis of phage populations evolved through multistage screening of landscape phage libraries against the MDA-MB-231 breast cancer cell line. The suggested combinatorial avidity selection model proposes a multistage accumulation of Elementary Binding Units (EBU), or Core Motifs (CorMs), in landscape phage fusion peptides, serving as evolutionary initiators for formation of SLiMs. Combinatorial selection has the potential to harness directed molecular evolution to create novel smart materials with diverse novel, emergent properties.
Dog Ecology, Bite Incidence, and Disease Awareness: A Cross-Sectional Survey among a Rabies-Affected Community in the Democratic Republic of the Congo
Authors: Mbilo Céline , Kabongo Jean-Baptiste , Pyana Pati Patient , Nlonda Léon , Nzita Raymond Williams , Luntadila Bobo , Badibanga Badivé , Hattendorf Jan , Zinsstag Jakob
Published: August 2019

Despite the existence of safe and efficacious human and animal rabies vaccines, millions of people remain at risk of exposure to this deadly zoonotic disease through bites of infected dogs. Sub-Saharan African countries, such as the Democratic Republic of the Congo (DRC), bear the highest per capita death rates from rabies where dog vaccination and availability of lifesaving post-exposure prophylaxis (PEP) is scarce. Mass dog vaccination is the most cost-effective and sustainable approach to prevent human rabies deaths. We conducted a cross-sectional household survey in a rabies-affected community in Matadi, DRC, to estimate the size of the owned dog population and dog bite incidence and assess knowledge and practices regarding rabies, as preparation for future mass dog vaccination campaigns. Our study revealed that the owned dog population in Matadi was almost ten times larger than assumed by local veterinary officials, with a large proportion of free-roaming unvaccinated dogs. The annual dog bite incidence of 5.2 per 1000 person years was high, whereas community rabies knowledge was low resulting in poor practices. Given these findings, human rabies deaths are likely to occur in this community. Lack of disease awareness could negatively affect participation in future mass dog vaccination campaigns. A public sensitization campaign is needed to promote appropriate rabies prevention (washing bite wounds and PEP) and control (dog vaccination) measures in this community.
Radiation as an In Situ Auto-Vaccination: Current Perspectives and Challenges
Authors: Goto Taichiro
Published: August 2019

Radiotherapy is generally considered to be a local treatment, but there have been reports of rare cases demonstrating abscopal effects in which antitumor effects have been observed in cancer lesions other than the irradiated site. This result is more likely to occur when immune checkpoint inhibitors are used in addition to radiotherapy. Certain radiation-induced chemokines and cytokines have immune-enhancing effects. Immune checkpoint inhibitors may strengthen these effects by stimulating antigen-presenting cells and effector cytotoxic T cells. To date, there is no consensus regarding the applicability of the abscopal effect in the clinical setting, including optimal methods for combining immune checkpoint inhibitors and irradiation. In this review, we highlight the evidence for interactions between cancer immunotherapy and radiotherapy and discuss the potential of such interactions for use in designing novel combination therapies.
A Regression Model of Stream Water Quality Based on Interactions between Landscape Composition and Riparian Buffer Width in Small Catchments
Authors: Pissarra Teresa Cristina Tarlé , Valera Carlos Alberto , Costa Renata Cristina Araújo , Siqueira Hygor Evangelista , Martins Filho Marcílio Vieira , Valle Júnior Renato Farias do , Sanches Fernandes Luís Filipe , Pacheco Fernando António Leal
Published: August 2019

Riparian vegetation represents a protective barrier between human activities installed in catchments and capable of generating and exporting large amounts of contaminants, and stream water that is expected to keep quality overtime. This study explored the combined effect of landscape composition and buffer strip width (L) on stream water quality. The landscape composition was assessed by the forest (F) to agriculture (A) ratio (F/A), and the water quality by an index (IWQ) expressed as a function of physico-chemical parameters. The combined effect (F/A × L) was quantified by a multiple regression model with an interaction term. The study was carried out in eight catchments of Uberaba River Basin Environmental Protection Area, located in the state of Minas Gerais, Brazil, and characterized by very different F/A and L values. The results related to improved water quality (larger IWQ values) with increasing values of F/A and L, which were not surprising given the abundant similar reports widespread in the scientific literature. But the effect of F/A × L on IWQ was enlightening. The interaction between F/A and L reduced the range of L values required to sustain IWQ at a fair level by some 40%, which is remarkable. The interaction was related to the spatial distribution of infiltration capacity within the studied catchments. The high F/A catchments should comprise a larger number of infiltration patches, allowing a dominance of subsurface flow widespread within the soil layer, a condition that improves the probability of soil water to cross and interact with a buffer strip before reaching the stream. Conversely, the low F/A catchments are prone to the generation of an overland flow network, because the absence of permanent vegetation substantially reduces the number of infiltration patches. The overland flow network channelizes runoff and conveys the surface water into specific confluence points within the stream, reducing or even hampering an interaction with a buffer strip. Notwithstanding the interaction, the calculated L ranges (45–175 m) are much larger than the maximum width imposed by the Brazilian Forest Code (30 m), a result that deserves reflection.
Stable Isotope Composition of River Waters across the World
Authors: Nan Yi , Tian Fuqiang , Hu Hongchang , Wang Lixin , Zhao Sihan
Published: August 2019

Stable isotopes of O and H in water are meaningful indicators of hydrological and ecological patterns and processes. The Global Network of Isotopes in Precipitation (GNIP) and the Global Network of Isotopes in Rivers (GNIR) are the two most important global databases of isotopes in precipitation and rivers. While the data of GNIP is almost globally distributed, GNIR has an incomplete spatial coverage, which hinders the utilization of river isotopes to study global hydrological cycle. To fill this knowledge gap, this study supplements GNIR and provides a river isotope database with global-coverage by the meta-analysis method, i.e., collecting 17015 additional data points from 215 published articles. Based on the newly compiled database, we find that (1) the relationship between δ18O and δ2H in river waters exhibits an asymmetric imbricate feature, and bifurcation can be observed in Africa and North America, indicating the effect of evaporation on isotopes; (2) multiple regression analysis with geographical factors indicates that spatial patterns of river isotopes are quite different across regions; (3) multiple regression with geographical and meteorological factors can well predict the river isotopes, which provides regional regression models with r2 of 0.50 to 0.89, and the best predictors in different regions are different. This work presents a global map of river isotopes and establishes a benchmark for further research on isotopes in rivers.
Combined Effect of Tides and Wind on Water Exchange in a Semi-Enclosed Shallow Sea
Authors: Shang Jiancheng , Sun Jian , Tao Lei , Li Yuanyi , Nie Zhenhua , Liu Haiying , Chen Rui , Yuan Dekui
Published: August 2019

The Bohai Sea is a semi-enclosed shallow sea in China, where the tides and wind are the dominant factors contributing to the water exchange with the Yellow Sea. However, existing studies on this water exchange primarily consider only the effect of tidal action, neglecting the contribution of wind. In this study, numerical models were used to simulate the hydrodynamic processes and tracer transport, with the consideration of both tides and wind. Based on the models, the two time scales, age and half-life, are applied to study the water exchange in the Bohai Sea quantitatively. The results show that the age and half-life decrease significantly when wind is included in the simulation, revealing that wind is an important contributor to the water exchange in such a semi-enclosed shallow sea. Under the combined forcing of tides and wind, the water transport in the Bohai Sea becomes clockwise, in contrast with the counterclockwise transport driven by the tides only. The seasonal-varying wind leads to a fluctuation of water exchange in an annual cycle, with the stronger water exchange in the northern (Liaodong Bay) and the western (Bohai Bay) regions of the Bohai Sea in winter and in the southern part (Laizhou Bay) in summer.
Improving the Accuracy of Hydrodynamic Simulations in Data Scarce Environments Using Bayesian Model Averaging: A Case Study of the Inner Niger Delta, Mali, West Africa
Authors: Haque Md Mominul , Seidou Ousmane , Mohammadian Abdolmajid , Djibo Abdouramane Gado , Liersch Stefan , Fournet Samuel , Karam Sara , Perera Edangodage Duminda Pradeep , Kleynhans Martin
Published: August 2019

In this paper, the study area was the Inner Niger Delta (IND) in Mali, West Africa. The IND is threatened by climate change, increasing irrigation, and dam operations. 2D hydrodynamic modelling was used to simulate water levels, discharge, and inundation extent in the IND. Three different digital elevation models (DEM) (SRTM, MERIT, and a DEM derived from satellite images were used as a source of elevation data. Six different models were created, with different sources of elevation data and different downstream boundary conditions. Given that the performance of the models varies according to the location in the IND, the variable under consideration and the performance criteria, Bayesian Model Averaging (BMA) was used to assess the relative performance of each of the six models. The BMA weights, along with deterministic performance measures, such as the Nash Sutcliffe coefficient (NS) and the Pearson’s correlation coefficient (r), provide quantitative evidence as to which model is the best when simulating a particular hydraulic variable at a particular location. After the models were combined with BMA, both discharge and water levels could be simulated with reasonable precision (NS > 0.8). The results of this work can contribute to the more efficient management of water resources in the IND.
Hydrogeological and Climatological Risks Perception in a Multi-Hazard Environment: The Case of Greece
Authors: Papagiannaki Katerina , Diakakis Michalis , Kotroni Vassiliki , Lagouvardos Kostas , Andreadakis Emmanuel
Published: August 2019

Climate-related hazards, such as wildfires and hydrogeological phenomena, cause extensive damages and casualties around the world. Despite the recent advances and technologies for risk mitigation, it is acknowledged that public risk perception is a critical factor for these tools to succeed. Greece and the broader Eastern Mediterranean is an area where, despite the diversity of natural disasters, there is a lack of understanding of the hazard types that people are most concerned with and how they measure against other groups of hazards (i.e., geophysical). This work uses an online survey targeting Greek people, aiming to provide a better understanding of their perception of different natural hazards. Statistical results show that people consider climate-related hazards less dangerous and likely to occur than earthquakes, which occur often as zero-impact events. Laymen may thus underestimate certain risks, which may inhibit appropriate preparation. Disaster experience was found to increase threat perceptions and to motivate preparedness. However, in what concerns climate-related hazards, the effect of experience may fade out over time. Awareness activities were found to associate with higher emergency response efficacy. Males exhibit lower risk perception and higher coping appraisals. However, prioritization of risks is almost identical between genders. Implications for risk management are discussed.
Assessing the Performance of CMIP5 Global Climate Models for Simulating Future Precipitation Change in the Tibetan Plateau
Authors: Jia Kun , Ruan Yunfeng , Yang Yanzhao , Zhang Chao
Published: August 2019

In this study, the performance of 33 Coupled Model Intercomparison Project 5 (CMIP5) global climate models (GCMs) in simulating precipitation over the Tibetan Plateau (TP) was assessed using data from 1961 to 2005 by an improved score-based method, which adopts multiple criteria to achieve a comprehensive evaluation. The future precipitation change was also estimated based on the Delta method by selecting the submultiple model ensemble (SMME) in the near-term (2006–2050) and far future (2051–2095) periods under Representative Concentration Pathways (RCP) scenarios RCP4.5 and RCP8.5. The results showed that most GCMs can reasonably simulate the precipitation pattern of an annual cycle; however, all GCMs overestimated the precipitation over TP, especially in spring and summer. The GCMs generally provide good simulations of the temporal characteristics of precipitation, while they did not perform as well in reproducing its spatial distributions. Different assessment criteria lead to inconsistent results; however, the improved rank score method, which adopts multiple criteria, provided a robust assessment of GCMs performance. The future annual precipitation was projected to increase by ~6% in the near-term with respect to the period 1961–2005, whereas increases of 12.3% and 16.7% are expected in the far future under RCP4.5 and RCP8.5 scenarios, respectively. Similar spatial distributions of future precipitation changes can be seen in the near-term and far future periods under the two scenarios, and indicate that the most predominant increases occurred in the north of TP. The results of this study are expected to provide valuable information on climate change, and for water resources and agricultural management in TP.
The Effect of Modifying a CFD-AB Approach on Fish Passage through a Model Hydraulic Dam
Authors: Gilmanov Anvar , Zielinski Daniel , Voller Vaughan , Sorensen Peter
Published: August 2019

The threat of invasive bigheaded carp swimming into the upper reaches of the Mississippi River (USA) demands new and effective approaches to block these species. To explore how navigational Lock and Dams (LDs) on the Mississippi River could be used to deter the upstream migration of invasive fish species, computer modelling that combined computational fluid dynamics (CFD) and agent-based (AB) fish passage model (CFD-AB model) could be used to hypothetically quantify the passage of bigheaded carp (Hypophthalmichthys spp.) through LDs. Agent-based fish (AB-fish) are always located on a node of the CFD mesh and move by selecting the neighboring node that minimizes fatigue. A possible limitation of this approach is that the AB-fish movement exhibits a dependence upon the CFD mesh. The proposed modified approach allows the AB-fish to occupy any point in the computational domain and to continually (within the size of the time step) update their minimum fatigue path. Computations in a simplified channel/dam structure show that the modified CFD-AB results are smoother swimming trajectories and increased estimates of fish passage when compared to the original CFD-AB model.
Numerical Simulation of the Sound Field of a Five-Stage Centrifugal Pump with Different Turbulence Models
Authors: Wang Li , Liu Houlin , Wang Kai , Zhou Ling , Jiang Xiaoping , Li Yu
Published: August 2019

To study the influence of the turbulence model on the sound field of pumps, the standard k-ε, Re-normalization Group (RNG) k-ε and Shear Stress Transfer (SST) k-ω models were employed to simulate flow and sound fields of a five-stage centrifugal pump with a vaned-diffuser. The vibration characteristics of the pump were simulated with the modal response method. A vibration experiment in the pump was carried out to verify the feasibility of the numerical simulation of the hydrodynamic noise in the pump. Results show that in the spectrum of internal and external noise, the peak value appears at axial passing frequency (APF) and its harmonic frequency. Compared with the standard k-ε model, the RNG k-ε and SST k-ω models show good consistence with the noise characteristics of experimental results, indicating the characteristic frequency and revealing the approximate behavior of the sound field in the pump. In general, the simulation of the sound field based on the RNG k-ε model is most appropriate for the multistage centrifugal pump with a vaned-diffuser.
MODELO EXPERIMENTAL DE MUCOSITE ORAL E INTESTINAL EM RATOS WISTAR
Authors: Wellington Dorigheto Andrade Vieira  , Akinori Cardozo Nagato  , Maria Inês da Cruz Campos
Published: August 2019

Introdução: A mucosite oral é considerada um efeito colateral agudo frequente do tratamento antineoplásico, com lesões ulcerativas de sintomatologia dolorosa, que acometem a cavidade bucal, devido ao tratamento antineoplásico. Para estudar esses efeitos colaterais, são necessários estudos em animais de experimentação, conhecer qual o melhor medicamento e tratamento. O objetivo é apresentar alternativas do modelo experimental de mucosite oral utilizando outro tipo de roedor. Métodos: Foi realizada uma pesquisa em base de dados Pubmed, Lilacs e Scielo, selecionando estudos de relevância para o tema. Discussão: Mucosite oral é descrita como alterações na mucosa bucal decorrentes do tratamento anticâncer. Vários estudos vêm sendo desenvolvidos como forma de tratamento e até mesmo sua prevenção; para isso diversos estudos utilizam modelos animais, sendo o hamster o mais utilizado, porém há outros tipos de roedores que podem ser utilizados como os ratos Wistars. Conclusão: Na ausência de hamsters é possível utilizar outros roedores para estudo da mucosite oral.
A multiplicidade de Locating Science Fiction
Authors: Luiz Felipe Baute
Published: August 2019

Resenha do livro Locating science fiction (2014), escrito por Andrew Milner.
A tradução dos nomes em Harry Potter
Authors: Nogueira Leite Isabella Aparecida
Published: August 2019

Este trabalho consiste na discussão de como e porque os nomes, tanto dos personagens como das criaturas em Harry Potter foram traduzidos. Para isso iremos utilizar somente a primeira obra: “Harry Potter e a Pedra Filosofal” de JK Rowling, pois além de ser a primeira obra da saga, é a única que possui dois títulos distintos em inglês. Iremos utilizar também como aporte teórico os artigos de Germana de Souza et al. e de Dalila Lopez que discutem sobre a tradução de nomes próprios. A nossa pesquisa é de cunho quantitativo, sendo feita uma análise de sete quadros contendo 38 nomes e 17 títulos de capítulos.Palavras-chaves: Harry Potter; tradução; tradução de nomes.  ABSTRACT: This paper aims to discuss how and why the characters’ names as well as the creature’s names were translated on the Harry Potter book series. To this end we will use the first book of the series: “Harry Potter and the Philosopher’s Stone” by J.K. Rowling, since it is the only one that has two different titles in English, and besides it is the first book. We will also use as a theoretical approach the articles by Germana de Souza et al. and by Dalila Lopez that talks about the first names translation. Our research has a quantitative method and so we are going to analyze eight tables containing 38 names and 17 chapter titles in English and translated. Keywords: Harry Potter; translation; names’ translation.
Review: GOURINAT, Jean-Baptiste (dir.). L’étique du stoïcien Hiéroclès. Villeneuve d’Ascq: Presses Universitaires du Septentrion, 2016. Pp. 175.ISBN 978-2-7574-1273-2.EUR 22,00.
Authors: Brito Rodrigo Pinto de
Published: August 2019

No abstract since it is a review...
Proposta de tradução do Discurso de agradecimento ao povo romano, de Cícero
Authors: Santos Gilson Charles dos
Published: August 2019

Ofereço uma tradução para o Discurso em agradecimento ao povo romano, de Cícero (57 AEC), acompanhada de breve introdução ao tema.
Tradução dos contos Cacoethes scribendi e A razão por trás da razão, de Charles Bukowski
Authors: Toledo Beatriz Furlan
Published: August 2019

No presente artigo são apresentadas duas propostas de tradução para o português dos contos Cacoethes Scribendi e The Reason Behind Reason, do livro Absence of the Hero, de Charles Bukowski. Primeiramente, busca-se se apresentar o poeta e escritor Charles Bukowski e situar temporalmente suas publicações traduzidas no Brasil. Procura-se discutir alguns aspectos particulares sobre a tradução das obras desse autor, bem como, trazer uma breve análise sobre os dois contos traduzidos. Por ser Bukowski um autor que, comprovadamente, trazia dados autobiográficos para as suas produções, ao analisar os dois contos do livro Absence of the Hero pretende-se também traçar essas ligações entre a representação do personagem que se espelha em traços da personalidade do autor. Bukowski colocou em seus romances elementos de sua vida encobertos por certo teor de ficção a fim de criar um personagem picaresco para o leitor, esses elementos são descritos ao longo de seus trabalhos. Além de trazer uma discussão sobre o autor e o teor autobiográfico de sua obra, são discutidos alguns caminhos tradutórios traçados para a tradução desses dois contos que ainda não possuem traduções publicadas em português.
Ars Amatoria, I, 89-134: o rapto das sabinas (tradução)
Authors: Duque Guilherme Horst
Published: August 2019

Tradução poética dos versos 89 a 134 do Livro I da Ars Amatoria de Ovídio, baseada na edição de E. J. Kenney (1995). Meu objetivo foi recriar em versos de 12 e de 10 sílabas efeitos sonoros e poéticos do texto fonte. O excerto traz uma versão do mito do rapto das mulheres Sabinas liderado por Rômulo enfatizando uma atmosfera erótica.
Tradução do discurso Contra os Sofistas de Isócrates
Authors: Lacerda Ticiano Curvelo Estrela de
Published: August 2019

Esta é a tradução do discurso Contra os Sofistas (390 a.C.) do ateniense Isócrates (436 - 338 a.C.), segundo a edição de Engelbert Drerup (Isocratis. Opera Omnia. Hildesheim & Leipzig: Georg Olms Verlag, 1906). Ela é precedida por um breve comentário introdutório a respeito do discurso, bem como de notas sobre a tradução. Ademais, também traduzo, previamente ao Contra os Sofistas, o "argumento de um gramático anônimo" a respeito do discurso, presente na edição de Mathieu & Brémond (Isocrate: Discours. Paris: Les Belles Lettres, 1929).
Os saberes profissionais do Professor de Matemática: contribuições da história da educação matemática
Authors: Valente Wagner Rodrigues , Bertini Luciane de Fatima , Morais Rosilda dos Santos
Published: August 2019

Este texto tem por objetivo explicitar que contribuições a história da educação matemática poderá dar à análise dos saberes profissionais do professor de matemática. O estudo realiza um inventário das recentes produções sobre a formação de professores e problematiza as conclusões dessas pesquisas. O artigo utiliza bases teórico-metodológicas sócio-históricas e também considera os resultados vindos de pesquisas realizadas no âmbito da história da educação matemática. Como resultado, o texto conclui pela necessidade de ampliação do intervalo temporal de análise da formação de professores, de modo a que se possa evidenciar a constituição e as transformações do saber profissional do professor de matemática.
O campo disciplinar da história das ideias: procedimentos e métodos de investigação
Authors: Ramalho Tiago Rego
Published: August 2019

O presente estudo visa aprofundar as características, os elementos e as particularidades inerentes ao campo metodológico da história das ideias. Desde logo, tentamos esclarecer as descontinuidades existentes entre o campo disciplinar da história das ideias e o campo disciplinar da história da Filosofia; e, contrapondo posições distintas, procuramos perceber através dos contributos de Quentin Skinner quais as possibilidades efetivas de autonomização de uma área disciplinar como a história das ideias.
Trabalhadores sob as ditaduras do Cone Sul em narrativas fílmicas
Authors: Lobo Valéria Marques
Published: August 2019

O artigo analisa filmes contextualizados nas ditaduras do Cone Sul protagonizados por trabalhadores. Através de cinco obras, discuto o papel do cinema na produção e na difusão do conhecimento acerca de um período repleto de histórias e de personagens pouco conhecidos. Os filmes apresentados são relevantes por desvelar histórias de indivíduos ou coletivos de trabalhadores sob o autoritarismo e também por sua trajetória particular.
A Coroa, o ouro e o pasto espiritual: por uma lógica da ação coletiva nos hospícios das Minas Gerais no século XVIII
Authors: Diana Marcelo Henrique Nogueira
Published: August 2019

Os hospícios na época moderna tinham como função receber e acomodar religiosos e viajantes, oferecendo-lhes abrigo e estadia durante as suas caminhadas e missões. Devido à própria volatilidade da riqueza do ouro, o rei D. João V mandou proibir a construção e a instalação de casas desse tipo nas Minas do século XVIII. Contudo, após uma série de pedidos feitos pelas Câmaras locais, os hospícios foram autorizados pelo rei. Neste artigo, analiso a documentação dos hospícios, produzida pelas Câmaras e pelo Conselho Ultramarino, com o objetivo de compreender a mudança de decisão do rei em relação à proibição e posterior permissão para a edificação dessas casas nas Minas colonial.
O antigo e o novo caminham juntos: A (re)organização judiciária na província de Minas Gerais entre 1833 e 1860
Authors: Sodré Elaine Leonara de Vargas
Published: August 2019

Este artigo tratará do sistema judiciário brasileiro no período imperial. A primeira proposta que expunha a reorganização daquele sistema surgiu com Código do Processo Criminal. Contudo, já na primeira década de funcionamento, apresentou várias deficiências. O Estado empregou mudanças e entre, avanços e retrocessos,passaram-se os anos. Aqui, o objetivo é analisar como se deu esse processo, em Minas Gerais, entre 1833 e 1860.
Coronelismo: uma análise historiográfica
Authors: Pinto Liliane Faria Corrêa
Published: August 2019

O artigo trata das diversas leituras em torno do coronelismo brasileiro, mencionando os autores Vitor Nunes Leal, Eul Soo Pang, Loiva Otero Felix, Paul Cammack, José Murilo de Carvalho, Edgar Carone, Maria Isaura Pereira de Queiroz, Raymundo Faoro, Amilcar Vianna Martins Filho e Cláudia Viscardi e lidando com osconceitos de coronelismo, clientelismo e mandonismo.
Diálogo assimétrico na historiografia brasileira: A Nova História entre os anos 1985 e 1994
Authors: Belieiro Thiago Granja , Cardoso Jr. Hélio Rebello
Published: August 2019

O artigo mobiliza a noção de diálogo assimétrico para caracterizar a posição da historiografia brasileira na historiografia global. A seguir, analisa o diálogo teórico e metodológico dos historiadores da Universidade de São Paulo com a historiografia francesa da Nova História, investigando características do Programa de Pósgraduação em História como lugar de produção, estudando ainda um conjunto de seis trabalhos defendidos na USP entre 1985 a 1994.
Um panorama histórico da Índia contemporânea: gêneses e desafios políticos, econômicos e religiosos numa democracia asiática pós-colonial
Authors: Landau de Carvalho Matheus
Published: August 2019

GANGULY, Šumit; MUKHERJI, Rahul. A Índia desde 1980. Rio de Janeiro: Apicuri, 2014, 216p.
O estado da arte da história transnacional: o discurso “corporativista-mítico” como campo de reflexões transnacionais
Authors: Costa Luiz Mário Ferreira
Published: August 2019

A ideia central deste paper é demonstrar como os métodos da história transnacional podem colaborar para uma melhor reflexão acerca da complexidade que envolve o estudo de um tipo de corporativismo, especialmente autoritário, conservador e conduzido por uma liderança mítica.
A Constituinte e a Constituição como instâncias do patrimônio cultural
Authors: Campos Yussef Daibert Salomão de
Published: August 2019

A relação estabelecida entre o exercício constituinte, tão caro à modernidade, a relevância da Constituição para o Estado Nacional e a formatação de uma identidade social erigida pelo patrimônio cultural é o objeto primeiro desse artigo. Compreender os meandros e as imbricações entre essas categorias basilares dos Estados Nacionais é a finalidade precípua.
O mundo do papel: a experiência jesuítica e a elaboração da Arte da Língua Kiriri
Authors: Santos Ana Luíse Silva Mecenas
Published: August 2019

O presente artigo visa analisar a experiência jesuítica por meio dos impressos de normatização da língua Kiriri. No intuito de discutir a cultura escriturária na produção de instrumentos de conversão pelos missionários que atuaram junto aos Kiriri, bem como o processo de tradução cultural na segunda metade do século XVII junto as missões do sertão da Bahia.
“Para a melhor felicidade e comodidade da população”: o arrendamento dos serviços de eletricidade, telefonia e viação urbana de Belo Horizonte, 1911-1912
Authors: Goodwin Junior James William
Published: August 2019

Este trabalho aborda o processo do arrendamento dos serviços de eletricidade, viação urbana e telefonia de Belo Horizonte, MG, em 1911-12, identificando suas linhas gerais a partir da leitura de diversas publicações do período. O texto explicita as implicações do arrendamento para o serviço telefônico, avançando na pesquisa em curso sobre o uso social desse artefato tecnológico na nova capital durante a Primeira República.
Viver nos tempos da Inquisição
Authors: Revista de História Locus
Published: August 2019

Resenha do Livro: NOVINSKY, Anita Waingort. Viver nos tempos da Inquisição. São Paulo: Perspectiva, 2018.
Comparative Analysis of Modified Granger-Ramanathan and Bates-Granger Methods to Combine Forecasts of the Dynamics of Economic Indicators
Authors: Frenkel A. A. , Volkova N. N. , Surkov A. A. , Romanyuk E. I.
Published: August 2019

Combining forecasts is one of the most effective and well-established methods for improving the accuracy of economic forecasting. This approach allows the use of all available information about the predicted phenomenon contained in individual forecasting methods. Moreover, today there are many approaches to construct weights, through which particular forecasts are combined.

But with a large variety of methods for constructing weight coefficients, there are a number of problems, primarily concerning the interpretation of the weight coefficients that affect the accuracy of forecasts. The purpose of this paper is to analyze the previously proposed approaches to modify the most popular methods for constructing the weighting coefficients of Granger-Ramanathan and Bates-Granger, which allow to solve the problem of the possibility of obtaining negative weights when combining forecasts. As well as to compare the accuracy of the results when using data modifications of the methods for combining forecasts with private forecasting methods and with the original methods of combining.

All the methods described in the work were used to predict some specific types of industrial products produced in Russia, presented as annual data for the period from 1952 to 2018: steel, coke, plywood and cement. Based on the developed forecasts, the accuracy of the obtained results was compared.

As a result of the analysis, it was determined that the combination of forecasts remains the most effective method for improving the accuracy of forecasting, and the modifications proposed by the authors to the methods for constructing weight coefficients deserve their further use in economic practice.
Development of Small Business in the Altay Territory in 2010-2015
Authors: Lesovykh S. V.
Published: August 2019

The article considers main trends in the small business of the Altay Territory according to results of 2011 and 2016 full-scale observations that follow the results of activities of small and medium-sized enterprises in 2010 and 2015.

In the introduction, the author argues the relevance of the economic and statistical analysis of small business, which is essential for its support, as it is one of the government’s priority areas of activity at all levels when it comes to solving problems of socio-economic development. There are characteristics of information support of the analysis related to the implementation of the Federal Law No. 209-FZ from July 24, 2007 «On small and medium business development in the Russian Federation» and the Order of the Government of the Russian Federation No. 201-r from February 14, 2009.

The body of the article successively focuses on some areas of analysis - from the general characteristics of small businesses to the factual analysis of individual aspects of activities of the economic entities under review (headcount, wages and revenues, fixed assets and the scope of investment activities). The features of small enterprises development by economic activity are analyzed separately. An integrated indicator of structural differences is used to assess the significance of structural changes in small businesses. A cluster analysis of the Altay Territory municipalities was carried out and they were rated according to the small business development level. In addition, the author assessed the contribution of small business of the Altay Territory to the development of small business in the Siberian Federal District and the Russian Federation.

The final section of the article draws conclusions from the authors’ own specific analysis that points to both positive and negative trends in the development of small business in the Altay Territory.
Rize Şehir Merkezinde Bulunan Banka ATM Cihazlarında Mikroorganizma Çeşitliliği
Authors: KAÇAR Zeynep Nur , KILINÇ Alev , YANIK Selin , YAMANTÜRK Zeynep , ÇOPUR ÇİÇEK Ayşegül
Published: August 2019

Amaç: Banka ATM makineleri toplumda en çok ortak kullanılan makinelerden biridir.Ellerin ve elle temas eden yüzeylerin mikroorganizma ile kolonizasyonu enfeksiyonların gelişiminde önemli yer tutmaktadır.Çalışmamızda Rize il merkezinde bulunan tuşlu ve dokunmatik ekranlı ATM'lerden alınan sürüntü örneklerinde üreyen mikroorganizmaların araştırılması amaçlanmıştır.Gereç ve Yöntemler: ATM’lerin ekranlarından ve tuşlarından eküvyonla örnek alınarak sıvı (Luria-BertaniBroth) ve katı (kanlı ve EMB) besiyerlerine ekim yapılmıştır.Üreyen mikroorganizmalar koloni morfolojileri ve Gram boyanma özelliklerine göre klasik yöntemlerle tanımlanmıştır. İzolatların tür düzeyinde tanımlanması için Vitek 2 Compact (bioMérieux, Fransa) otomatize sistem kullanılmıştır. Metisilin direncini saptamada sefoksitin disk difüzyon testi kullanılmıştır. Mayaların tanımlamasında DNA dizi analizi yapılmıştır. Bulgular: Toplam 42 ATM’nin ekran ve tuşlarından alınan toplam 84 örneğin hepsinde üreme olmuştur. Ayrıca bu üremelerden sadece 4 tanesi sadece Bacillus spp. üremesi ile tek tip, 13‘ünde 2 tip ve diğerleri en az 3 tip mikroorganizma ile polimikrobiyal üreme idi. Toplamda 330 mikroorganizma üremiştir. Bunların 41’inde (%12,42) metisilin duyarlı koagülaz negatif stafilokok, 8’inde (%2,42) metisilin duyarlı Staphylococcusaureus, 6’sında (%1,81) metisilin dirençli S.aureus, 67’sinde (%20,3) metisilin dirençli koagülaz negatif Staphylococcus,103’ünde (%31,21) mikrokok, 43’ünde (%13,03) Bacillus spp, 9’unda (%2,72) Enterococcus spp.,37’sinde (%11,21) Streptococcus spp.,5’inde (%1,51) non-fermenter Gram negatif basil, 4’ünde (%1,21) Gram negatif enterik basil, 7’sinde (%2,12) mantar görülmüştür.Mantarların DNA dizi analizinde Acremonium spp., Amblyosporium spp., Corynascus spp., Penicillium spp. ve Scopulariopsis spp. tespit edilmiştir.Sonuç: Ülkemizde ATM’lerde mikroorganizma araştırılması ile ilgili sınırlı sayıda çalışma yapılmıştır. Çalışmamızda nonfermenter basil, Neisseria spp. daha az saptanırken, küf daha yüksek oranda görülmüştür. Kullanımı daha az olan ATM'lerde Bacillus spp. ve küf üremesinin fazla olması dikkat çekmiştir.Hijyen koşulları kadar Rize’nin nemli bir bölge olması da buna katkı sağlamıştır.Ayrıca çalışmamızda üreyen Gram negatif enterik basillerin özellikle şehir merkezinde lokanta, lokanta, şarküteri gibi yiyecek sektöründe hizmet veren yerlere yakın ATM’lerde üremesi önemli bir sonuç olarak karşımıza çıkmaktadır.Bulaş kaynağı olması açısından toplumun ortak kullandığı bu gibi yerlerin hijyeninde banka yetkililerinin de dezenfeksiyon konusunda dikkatli olmaları gerekmektedir.
Deteksi Intrusi Jaringan dengan K-Means Clustering pada Akses Log dengan Teknik Pengolahan Big Data
Authors: Ridho Farid , Kusuma Arya Aji
Published: August 2019

Keamanan jaringan, adalah salah satu aspek penting dalam terciptanya proses komunikasi data yang baik dan aman. Namun, masih adanya serangan yang efektif membuktikan bahwa sistem keamanan yang berlaku belum cukup efektif untuk mencegah dan mendeteksi serangan. Salah satu metode yang dapat digunakan untuk mendeteksi serangan ini adalah dengan dengan Intrusion Detection System (IDS). Besarnya data (volume), cepatnya perubahan data (velocity), serta variasi data (variety) merupakan ciri-ciri dari Big data. Akses log, secara teori termasuk dalam kategori ini sehingga dapat dilakukan pemrosesan menggunakan teknologi bigdata dengan Hadoop. Hal ini mendorong penulis untuk dapat menerapkan metode pengolahan baru yang dapat mengatasi perkembangan data tersebut, yaitu Big data. Penelitian ini dilakukan dengan menganalisis akses log dengan K-Means Clustering menggunakan metode pengolahan bigdata. Penelitian menghasilkan satu model yang dapat digunakan untuk mendeteksi sebuah serangan dengan probabilitas deteksi sebesar 99.68%. Serta dari hasil perbandingan kedua metode pengolahan bigdata menggunakan pyspark dan metode tradisional menggunakan python standar, metode bigdata memiliki perbedaan yang signifikan dalam waktu yang dibutuhkan dalam eksekusi program.
Implementation Of Information Systems On E-commerce Websites As Media To Deliver Information
Authors: Alwiyah Alwiyah , Greisy Chloe , Afitri Afni
Published: August 2019

Indonesia, which has entered the industrial era 4.0, has affected all aspects of its citizens' lives,including the buying and selling process. The buying and selling process currently uses a lot oftechnology. The process certainly makes it easier for people to use it only with a publiccellphone to shop easily. On an e-commerce website, of course it is used for buying and sellinggoods. This research was conducted at Raharja University where there is a center for servicefacilities for the needs of students. The service facility is called Raharja Internet Cafe which ismade to serve every student activity related to lecture needs such as print, scan, search forlecture material, work on assignments and others. At Raharja Internet Cafe currently has awebsite to order their needs. But the system has only recently been applied recently. With thenew website being implemented, students have not yet recognized what items or facilities areprovided on the website. The purpose of this research is to explain with the information systemon the website students can see the goods or facilities provided. This research uses a qualitativeapproach and also literature study. The results of this study are expected so that the informationsystem provided on the Raharja Internet Cafe website can be useful for students using thesefacilities.
Traffic Light Timer Control Using Raspberry Pi
Authors: Philip Armandio , Putri Cheetah Savana , Arifanggi Putra Maulana
Published: August 2019

As time goes by and the development of the times is very rapid increase in the number of vehicle volumes is increasing from year to year, coupled with automotive manufacturers who release their products at prices below the standard. This of course can increase the volume of congestion which is the main problem, very heavy traffic causes more time wasted and consumes fuel. The solution offered to overcome the congestion problem is a Timer Traffic Light control system, which is a traffic management system on each road segment used to reduce congestion in traffic lights that occur in big cities today. For the future, this is very much needed, given the increasing number of vehicles queuing at the traffic light. In this study a controller model of Timer Traffic Light was created based on image processing with the Background Subtraction method using the Raspberry Pi. The Background Subtraction method is used to process images containing objects that have been captured on the highway using a camera, the images obtained can classify the condition of the road with parameters of empty, medium, and solid conditions. The images obtained are then forwarded to the Timer Traffic Light controller system with the hardware and software used in this study.
Quality Control for Media Digitization Projects
Authors: Casey Michael
Published: August 2019

This article defines types of quality control and explores risk management strategies that are broadly applicable to any organization engaged in media digitization for long-term preservation. It uses the quality control system for audio and video digitization that was developed by Indiana University’s Media Digitization and Preservation Initiative to provide examples and illustrations of these ideas.
Degralescence, Prince Codec, and the Kingdom of Media
Authors: Casey Michael
Published: August 2019

Once upon a time, a king and queen ruled the kingdom of Media. Media was a peaceful land that was home to all things audio and video. Its subjects lived happy analog lives where preservation, access, and the means of production all revolved around their physical forms. But the king and queen had felt the winds of change blowing across their lands. They had heard tell of an unspeakable evil lurking about their borders. And they knew that the old ways could hold fast no longer.
The retrospective evaluation of clinical and demographic features of children with psoriasis
Authors: DEMİR Mahmut , AKSOY Mustafa
Published: August 2019

Background:
Psoriasis is an immune-mediated inflammatory dermatosis and constitutes 4% of
the pediatric dermatosises. In our study, evaluation of the clinical and
demographic characteristics of children with psoriasis has been aimed.Methods: 70 children with
psoriasis were included to the study. Parameters such as age, gender, disease,
age of onset, joint or nail involvement, clinical type, distribution of
lesions, severity of the disease, family history, accompanying disease,
received/receiving treatments, smoking habits and body mass index were
recorded. The data were statistically analyzed.Results: 36 of the patients
were girls (51.4%) and girl/boy ratio was: 1.058/1. Average age of onset was
8.01±4.56. The most frequent age of onset was 0-5 (%34.28). 31.40% of the
patients had family history, 8.57% of them had accompanying disease, 10% of
them had joint involvement, 18.57% of them had nail involvement and 8.57% of
them were smoking. The most frequent clinical type was plaque type (68.57%),
the most frequent parts that the disease was observed were hairy skin/face
areas (74.28%), and the most frequently used systemic agent was methotrexate
(18.57%).Conclusion:
Our results were mostly compatible with previous study results. In literature,
the amounts of studies that evaluate the clinic and sociodemographic
characteristics of the children with psoriasis are few and data are quite
variational.
Doğumsal nazolakrimal kanal tıkanıklığı tedavisinde sondalama yönteminin etkinliği ve zamanlamasının başarıya etkisi
Authors: TOPTAN Müslüm
Published: August 2019

Amaç: Doğumsal nazolakrimal kanal
tıkanıklığı (DNLKT) olan hastalarda sondalama yönteminin etkinliğini ve yaş
gruplarına göre başarı oranlarını değerlendirmek.Materyal
ve Metot:
Bu çalışmada, DNLKT nedeni ile 2016-2019 yılları arasında sondalama işlemi
uygulanan hastaların kayıtları retrospektif olarak incelendi. Hastaların
sondalama yapıldığı zamandaki yaşı, işlem sonrası epifora varlığı, sulanma
yakınmalarının durumu ve floresein kaybolma testinin sonuçları not edildi.
Ameliyat sonrası dönemde işlemin başarısı yaş gruplarına göre değerlendirildi.Bulgular: DNLKT tanısı alan 45 kız (%58.5), 32
erkek (%41.5) toplam 77 hasta çalışmaya alındı. Olguların yaş ortalaması
18.8±10.4  ay (2-39 ay) ve ortalama takip
süresi 11.6±7.6 ay (6-18 ay) idi. Hastaların 35’ inde sağ (%37.2), 42’ sinde sol
(%44.7), 17’ inde her iki gözüne (%22.1), toplam 94 göze sondalama uygulandı.
Hastalar başvuru esnasındaki yaşlarına göre dört farklı gruba ayrıldı. Birinci
grupta (0-12 aylık) sondalama ile %100, ikinci grupta (13-24 aylık) 1. sonda
uygulaması ile %90.0, 2. sondalama ile %97.4 oranında başarı sağlandı. Üçüncü
grupta (25-36 ay) sondalama ile %66.7 oranında başarıyla uygulandı. Dördüncü
grupta (37-48 ay arası) sondalama tedavisi ile % 56.2 oranında başarı elde
edildi.  

Sonuç: Hidrostatik masaj tedavisi ile
düzelmeyen DNLKT olguları için sondalama işlemi erken yaş gruplarında etkili
bir tedavi şeklidir. Hastanın yaşı arttıkça başarı şansı azalacağı için
sondalama uygulamasında geç kalınmaması gerekmektedir.