bluuebunny/crossref_metadata_2025 huggingface dataset:
A Novel Gel Polymer Electrolyte by Thiol-Ene Click Reaction Derived from CO2-Based Polycarbonate for Lithium-Ion Batteries
Authors: Luo Wenhan , Deng Kuirong , Wang Shuanjin , Ren Shan , Han Dongmei , Wang Yufei , Xiao Min , Meng Yuezhong
Published: July 2020

Here, we describe the synthesis of a CO2-based polycarbonate with pendent alkene groups and its functionalization by grafting methoxypolyethylene glycol in view of its application possibility in gel polymer electrolyte lithium-ion batteries. The gel polymer electrolyte is prepared by an in-situ thiol-ene click reaction between polycarbonate with pendent alkene groups and thiolated methoxypolyethylene glycol in liquid lithium hexafluorophosphate electrolyte and exhibits conductivity as remarkably high as 2.0×10−2 S cm−1 at ambient temperature. To the best of our knowledge, this gel polymer electrolyte possesses the highest conductivity in all relevant literatures. A free-standing composite gel polymer electrolyte membrane is obtained by incorporating the gel polymer electrolyte with electrospun polyvinylidene fluoride as a skeleton. The as-prepared composite membrane is used to assemble a prototype lithium iron phosphate cell and evaluated accordingly. The battery delivers a good reversible charge-discharge capacity close to 140 mAh g-1 at 1 C rate and 25°C with only 0.022% per cycle decay after 200 cycles. This work provides an interesting molecular design for polycarbonate application in gel electrolyte lithium-ion batteries.
Free Fatty Acids in CSF and Neurological Clinical Scores: Prognostic Value for Stroke Severity in ICU
Authors: Gaber Sayed , Ibrahim ElGazzar Sherine , Qenawi Mahmoud , Abbas Nora Ismail Mohamed
Published: July 2020

Introduction. Brain ischemia initiated significant increase in FFAs in animal studies. Accumulation of FFA can lead to liberation of inflammatory byproducts that contribute to neuronal death. Increased risk of systemic thromboembolism was seen in animal models after FFA infusion possibly through activation of factor XII by stearic acids. The clinical studies that examined the relation between stroke in humans and CSF biomarkers are infrequent. Aim of Work. We tried to evaluate the potential role of FFAs in CSF in the diagnosis and the prognosis of ICU patients with AIS while comparing the results to traditional neurological scoring systems. Patients and Methods. Our study included 80 patients who were admitted to ICU with acute ischemic stroke (AIS) within 24 hours of the onset of cerebral infarction. CSF samples were obtained at admission. The FFA levels were measured using the sensitive enzyme-based colorimetric method. The NIHSS, GCS, and mRS were evaluated at admission and at 30 days. Univariate and multivariate analysis were used to evaluate the stroke outcome according to FFA levels in CSF. Results. Worsening of the GCS (<7) at 30 days showed a significant correlation with FFA in CSF. The ROC curve showed a cutoff value of 0.27 nmol/µl, sensitivity of 62.9%, and specificity of 72.2%. There was a significant correlation between FFA in CSF and the mRS >2 at 30 days. The ROC curve showed a cutoff value of 0.27 nmol/µl, specificity of 69.2%, and sensitivity of 59.7%. There was a significant correlation between FFA in CSF and the NIHSS ≥ 16 at 30 days. The ROC curve showed a cutoff value of 0.27 nmol/µl, specificity of 72.2%, and sensitivity of 62.9%. Our study subdivided patients according to infarction volume and compared the 2 subgroups with FFA in CSF. We found a significant difference between 2 subgroups. FFA levels showed a positive correlation with infarction volume ≥145 ml. The ROC curve showed a cutoff value of 0.25 nmol/µl, sensitivity of 76.9%, and specificity of 71.4%. Our study showed that FFA in CSF was a significant predictor of all-cause mortality (0.37 + 0.26, P value 0.007). The ROC curve showed a cutoff value of 0.27, specificity of 72.2%, and sensitivity of 62.9%. There was a positive correlation between FFA in CSF and neurological causes of mortality (0.48 + 0.38, P value 0.037). The ROC curve showed a cutoff value of 0.37 nmol/µl, specificity of 76.1%, and sensitivity of 61.5%. Conclusion. FFA in CSF may serve as an independent prognostic biomarker for assessing the prognosis of acute ischemic stroke and the clinical outcome. It might be a useful biomarker for early detection of high-risk patients for poor outcome and hence more aggressive treatment.
Physicochemical and Vibration Analysis of Christmas Tree Four-Way Flange Failure under Fracturing Process
Authors: Zhou Zhaoming , Gong Dawen , Yang Kelong , Zeng Zhong , Xiao Zhou
Published: July 2020

When a wellhead gas production tree in a certain oilfield block fracturing completed 12 layers and 22 layers and then the bottom-up discharge operation was performed, the Wellhead four-way suddenly suffered erosion failure. This is the seventh failure of this operation. In order to obtain the cause of failure, the chemical analysis, hardness testing, tensile property testing, and finite element structural dynamic analysis are used to analyze the failure of the cross connection. The results of physical and chemical analysis show that the chemical composition, hardness, and tensile properties of the failed parts meet the requirements of the standard, not the problem of the material of the work piece. Due to the high-frequency vibration generated by the three-phase fluid in the pipeline during the discharge process, different types of vibration and deformation of the four-way valve and the valve body occur. The dimensions of the on-site structural parts were measured, and the bolt sizes were found to be different. A finite element model was established based on the measured data for dynamic analysis. Through physical and chemical tests and theoretical calculations, it is found that the cause of failure is the unbalanced load and resonance of the bolt, and the nut undercuts under high-frequency vibration, which causes leakage at the flange connection and eventually causes erosion failure. It is recommended to regularly use an electronic torque wrench to test the pretightening force of each bolt to prevent vibration and failure due to inconsistent pretightening force of the bolts.
Ankle‐Brachial Index as the Best Predictor of First Acute Coronary Syndrome in Patients with Treated Systemic Hypertension
Authors: Myslinski Wojciech , Stanek Agata , Feldo Marcin , Mosiewicz Jerzy
Published: July 2020

Objective. The objective of our study was to evaluate the incidence of target organ damages (TOD) in patients with arterial hypertension and the first ever episode of myocardial infarction (N‐STEMI or STEMI) and to determine which of the analyzed kinds of TOD had the highest predictive value for the assessment of the likelihood of acute coronary syndrome (ACS). Material and Methods. The study group consisted of 51 patients with treated systemic hypertension, suffering from the first episode of myocardial infarction (N‐STEMI or STEMI), confirmed by coronary angiography and elevation of troponin. The control group consisted of 30 subjects with treated hypertension and no history of myocardial ischaemia. In all subjects’ measurements of blood lipids, hsCRP and eGFR were measured. TOD, such as intima‐media thickness (IMT), presence of atherosclerotic plaques, ankle‐brachial index (ABI), and left ventricular hypertrophy, were assessed. Results. Age, BMI, blood pressure, and time since diagnosis of hypertension did not differ between the study groups. There were no differences regarding blood lipids and eGFR, while hsCRP was significantly increased in the study group. The left ventricular mass index was similar in both groups. Patients with myocardial infarction had significantly increased IMT and decreased ABI. The statistical analysis revealed that only ABI was the most significant predictor of ACS in the study group. Conclusion. Among several TOD, ABI seems to be the most valuable parameter in the prediction of ACS.
Comparison of Common Methods for Precision Volume Measurement of Hematoma
Authors: Chen Minhong , Li Zhong , Ding Jianping , Lu Xingqi , Cheng Yinan , Lin Jiayun
Published: July 2020

Purpose. Our aim is to conduct analysis and comparison of some methods commonly used to measure the volume of hematoma, for example, slice method, voxelization method, and 3D-Slicer software method (projection method). Method. In order to validate the accuracy of the slice method, voxelization method, and 3D-Slicer method, these three methods were first applied to measure two known volumetric models, respectively. Then, a total of 198 patients diagnosed with spontaneous intracerebral hemorrhage (ICH) were recruited. The patients were split into 3 different groups based on the hematoma size: group 1: volume<10 ml (n=89), group 2: volume between 10 and 20 ml (n=59), and group 3: volume>20 ml (n=50). And the shape of the hematoma was classed into regular (round to ellipsoid) with smooth margins (n=76), irregular with frayed margins (n=85), and multilobular (n=37). The slice method, voxelization method, and 3D-Slicer method were adopted to measure the volume of hematoma, respectively, considering the nonclosed models and the models which may contain inaccurate normal information during CT scan. Moreover, the results were compared with the 3D-Slicer method for closed models. Results. There was a significant estimation error (P<0.05) using these three methods to calculate the volume of the closed hematoma model. The estimated hematoma volume was calculated to be 14.2086743±0.900559087 ml, 14.2119130±0.900851812 ml, and 14.2123825±0.900835916 ml using slice method 1, slice method 2, and the voxelization method, respectively, compared to 14.212656±0.900992371 ml using the 3D-Slicer method. The mean estimation error was -0.00398172 ml, -0.00074303 ml, and -0.00027354 ml caused by slice method 1, slice method 2, and voxelization method, respectively. There was a significant estimation error (P<0.05), applying these three methods to calculate the volume of the nonclosed hematoma model. The estimated hematoma volume was calculated to be 14.1928246±0.902210314 ml using the 3D-Slicer method. The mean estimation error was calculated to be -0.00402121 ml, -0.00078237 ml, -0.00031288 ml, and -0.01983136 ml using slice method 1, slice method 2, voxelization method, and 3D-Slicer method, respectively. Conclusions. The 3D-Slicer software method is considered as a stable and capable method of high precision for the calculation of a closed hematoma model with correct normal direction, while it would be inappropriate for the nonclosed model nor the model with incorrect normal direction. The slice method and voxelization method can be the supplement and improvement of the 3D-Slicer software method, for the purpose of achieving precision medicine.
Extracorporeal Cardiopulmonary Resuscitation (ECPR) for Out-of-Hospital Cardiac Arrest due to Pulseless Ventricular Tachycardia/Fibrillation
Authors: Boudoulas Konstantinos Dean , Whitson Bryan A. , Keseg David P. , Lilly Scott , Baker Cindy , Attar Talal , Capers Quinn , Gumina Richard J. , Mast David W. , Satyapriya Sree Veena , Davenport Dixie , Hazlett Melinda , Mokadam Nahush , Magorien Raymond , Mazzaferri Ernest L.
Published: July 2020

Background. Survival rates for out-of-hospital cardiac arrest are very low and neurologic recovery is poor. Innovative strategies have been developed to improve outcomes. A collaborative extracorporeal cardiopulmonary resuscitation (ECPR) program for out-of-hospital refractory pulseless ventricular tachycardia (VT) and/or ventricular fibrillation (VF) has been developed between The Ohio State University Wexner Medical Center and Columbus Division of Fire. Methods. From August 15, 2017, to June 1, 2019, there were 86 patients that were evaluated in the field for cardiac arrest in which 42 (49%) had refractory pulseless VT and/or VF resulting from different underlying pathologies and were placed on an automated cardiopulmonary resuscitation device; from these 42 patients, 16 (38%) met final inclusion criteria for ECPR and were placed on extracorporeal membrane oxygenation (ECMO) in the cardiac catheterization laboratory (CCL). Results. From the 16 patients who underwent ECPR, 4 (25%) survived to hospital discharge with cerebral perfusion category 1 or 2. Survivors tended to be younger (48.0 ± 16.7 vs. 59.3 ± 12.7 years); however, this difference was not statistically significant (p=0.28) likely due to a small number of patients. Overall, 38% of patients underwent percutaneous coronary intervention (PCI). No significant difference was found between survivors and nonsurvivors in emergency medical services dispatch to CCL arrival time, lactate in CCL, coronary artery disease severity, undergoing PCI, and pre-ECMO PaO2, pH, and hemoglobin. Recovery was seen in different underlying pathologies. Conclusion. ECPR for out-of-hospital refractory VT/VF cardiac arrest demonstrated encouraging outcomes. Younger patients may have a greater chance of survival, perhaps the need to be more aggressive in this subgroup of patients.
A Novel Robust Student’s t-Based Cubature Information Filter with Heavy-Tailed Noises
Authors: Shui Yongtao , Wang Xiaogang , Qin Wutao , Wang Yu , Pang Baojun , Cui Naigang
Published: July 2020

In this paper, a novel robust Student’s t-based cubature information filter is proposed for a nonlinear multisensor system with heavy-tailed process and measurement noises. At first, the predictive probability density function (PDF) and the likelihood PDF are approximated as two different Student’s t distributions. To avoid the process uncertainty induced by the heavy-tailed process noise, the scale matrix of the predictive PDF is modeled as an inverse Wishart distribution and estimated dynamically. Then, the predictive PDF and the likelihood PDF are transformed into a hierarchical Gaussian form to obtain the approximate solution of posterior PDF. Based on the variational Bayesian approximation method, the posterior PDF is approximated iteratively by minimizing the Kullback-Leibler divergence function. Based on the posterior PDF of the auxiliary parameters, the predicted covariance and measurement noise covariance are modified. And then the information matrix and information state are updated by summing the local information contributions, which are computed based on the modified covariance. Finally, the state, scale matrix, and posterior densities are estimated after fixed point iterations. And the simulation results for a target tracking example demonstrate the superiority of the proposed filter.
An Adaptive Deep Transfer Learning Model for Rumor Detection without Sufficient Identified Rumors
Authors: Guo Meicheng , Xu Zhiwei , Liu Limin , Guo Mengjie , Zhang Yujun
Published: July 2020

With the extensive usage of social media platforms, spam information, especially rumors, has become a serious problem of social network platforms. The rumors make it difficult for people to get credible information from Internet and cause social panic. Existing detection methods always rely on a large amount of training data. However, the number of the identified rumors is always insufficient for developing a stable detection model. To handle this problem, we proposed a deep transfer model to achieve accurate rumor detection in social media platforms. In detail, an adaptive parameter tuning method is proposed to solve the negative transferring problem in the parameter transferring process. Experiments based on real-world datasets demonstrate that the proposed model achieves more accurate rumor detection and significantly outperforms state-of-the-art rumor detection models.
Determinants of Tobacco Smoking Addiction in Rural Indonesian Communities
Authors: Swatan Jovian Philip , Sulistiawati Sulistiawati , Karimah Azimatul
Published: July 2020

Purpose. To analyze the determinants of tobacco smoking addiction in rural areas. Methods. A cross-sectional study was conducted on February 2020. The self-administered questionnaire (α = 0.908) and Perceived Stress Scale–10 were used as tobacco smoking determinants and the WHO ASSIST questionnaire V3.0 to determine its addiction risk. Their correlations were analyzed by Spearman’s rank-order approach using the SPSS version 23.0. Results. Among 75 male respondents that participated in this study, those on low, moderate, and high addiction risk were 45 (60.00%), 23 (30.67%), and 7 (9.33%), respectively, and significantly correlated with the research questionnaire that consisted three parts: 1. awareness toward the health risk; 2. social control; 3. mass media role in tobacco smoking (p=0.014, 0.004, and 0.009 respectively), but there was no significant correlation with the stress level (p=0.287). Conclusion. Increased awareness toward the health risk, good social control, and mass media reporting the danger of tobacco smoking is significantly in correlation with the decreased addiction in rural areas. However, the high perceived stress has no correlation with its increase.
Dynamics of a Nonlinear Energy Harvesting System in Time-Delayed Feedback Control under Stochastic Excitations
Authors: Zhang Shuling , Zhang Ying , Sun Zhongkui , Duan Xiaxia
Published: July 2020

A time-delayed feedback control is applied to a nonlinear piezoelectric energy harvesting system excited by additive and multiplicative Gaussian white noises to improve its energy harvesting performance. An equivalent decoupling system can be obtained by using a variable transformation. Based on the standard stochastic averaging method, the Fokker–Plank–Kolmogorov equation and the stationary probability density functions of the amplitude, displacement, and velocity of the harvester are obtained, respectively. In addition, the approximate expressions of mean square electric voltage and the mean extracted output power are derived. Finally, the paper explores the influences of parameters on the mean square electric voltage. The results show that noise intensity, time delay, feedback strength, time constant ratio, and coupling coefficients have great influences on the mean square electric voltage. The accuracy of the theoretical method is verified by the Monte Carlo simulation.
Evaluation and Design of Power Controller of Two-Axis Solar Tracking by PID and FL for a Photovoltaic Module
Authors: Ontiveros Joel J. , Ávalos Carlos D. , Loza Faustino , Galán Néstor D. , Rubio Guillermo J.
Published: July 2020

Solar trackers represent an essential tool to increase the energy production of photovoltaic modules compared to fixed systems. Unlike previous technologies where the aim is to keep the solar rays perpendicular to the surface of the module and obtain a constant output power, this paper proposes the design and evaluation of two controllers for a two-axis solar tracker, which maintains the power that is produced by photovoltaic modules at their nominal value. To achieve this, mathematical models of the dynamics of the sun, the solar energy obtained on the Earth’s surface, the two-axis tracking system in its electrical and mechanical parts, and the solar cell are developed and simulated. Two controllers are designed to be evaluated in the solar tracking system, one Proportional-Integral-Derivative and the other by Fuzzy Logic. The evaluation of the simulations shows a better performance of the controller by Fuzzy Logic; this is because it presents a shorter stabilization time, a transient of smaller amplitude, and a lower percentage of error in steady-state. The principle of operation of the solar tracking system is to promote the orientation conditions of the photovoltaic module to generate the maximum available power until reaching the nominal one. This is possible because it has a gyroscope on the surface of the module that determines its position with respect to the hour angle and altitude of the sun; a data acquisition card is developed to implement voltage and current sensors, which measure the output power it produces from the photovoltaic module throughout the day and under any weather conditions. The results of the implementation demonstrate that a Fuzzy Logic control for a two-axis solar tracker maintains the output power of the photovoltaic module at its nominal parameters during peak sun hours.
An Unusual Case of Radicular Pain Caused by Bilateral Lumbar Synovial Cyst: A Case Report and Review of the Literature
Authors: Ruiz-Picazo David , Ramírez-Villaescusa José , Verdejo-González Ana
Published: July 2020

Introduction. Spinal synovial cysts (SSCs) constitute an uncommon degenerative lesion of the spine. They are usually asymptomatic but they may also cause symptoms of variable severity. SSCs are benign growths adjoining the facet joints that may induce low back pain, lumbar radiculopathy, and neurological deficit. There are different treatment options that range from conservative management to interventions like image-guided epidural steroid injection or direct cyst puncture and finally to open or endoscopic spinal canal decompression and spinal bone fusion with/without instrumentation. A discussion of current management options for this unusual disease is presented. Material and Methods. A 52-year-old female patient presented with low back pain and left leg pain. Plain radiography demonstrated instability at the L4-L5 level. Magnetic resonance images (MRIs) revealed a bilateral cystic lesion at the L4-L5 level with associated instability and degenerative disc disease at the level L5-S1. Initially, conservative treatment was performed by aspiration of the left cyst and infiltration with corticosteroids with improvement of the pain for 1 year. After this period, the radicular and the low back pain reoccurred. Results. Following leg pain recurrence, a hybrid L4-S1 fusion was performed. After surgery, there was clinical improvement and six months later, the patient returned to daily activities. The radiological study after five-year follow-up shows adequate implant position, without signs of loosening, compatible with solid fusion. Conclusion. After reviewing the literature, the optimal management for patients with symptomatic lumbar synovial cyst must be very individualized, which is essential to achieve a favorable outcome.
Experimental Study of the Rock Mechanism under Coupled High Temperatures and Dynamic Loads
Authors: An Huaming , Zeng Tongshuai , Zhang Zhihua , Liu Lei
Published: July 2020

With the development of modern society, geomaterials are widely used for infrastructure. These materials often experience dynamic loading and high temperature, which significantly influences the mechanical behaviour of the materials. This research focuses on the effects of the loading rate and high temperature on rock mass in terms of rock mechanism. A state‐of‐the‐art review of rock mechanism under coupled dynamic loads and high temperatures is conducted first. The rock mechanism under static and dynamic loads is introduced. The marble is taken as the rock material for the test, while the split‐Hopkinson pressure bar system is used to take the dynamic tests. In addition, the principles of the split‐Hopkinson pressure bar are introduced to obtain the dynamic parameters. The fracture patterns of the uniaxial compressive strength test and the Brazilian tensile strength test are obtained and compared with those well documented in the literature. Some curves for the relationships among the loading rate, strain, temperature, compressive or tensile strengths are explained. It is conduced that with the increase of the loading rate, the rock strength increases, while with the increase of the temperature, the rock strength decreases.
FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma
Authors: Xiao Li , Li Xiaodi , Mu Zekun , Zhou Jianwen , Zhou Peng , Xie Chen , Jiang Songshan
Published: July 2020

Malignant glioma constitutes one of the fatal primary brain tumors in adults. Such poor prognosis calls for a better understanding of cancer-related signaling pathways of this disease. Here we elucidate a MYC-miRNA-MXI1 feedback loop that regulates proliferation and tumorigenesis in glioma. MYC suppressed MXI1 expression via microRNA-155 (miR-155) and the microRNA-23a∼27a∼24-2 cluster (miR-23a cluster), whereas MXI1, in turn, inhibited MYC expression by binding to its promoter. Overexpression of miR-155 and the miR-23a cluster promoted tumorigenesis in U87 glioma cells. Furthermore, fat mass and obesity-associated protein (FTO), an N6-methyladenosine (m6A) RNA demethylase, regulated the loop by targeting MYC. The ethyl ester form of meclofenamic acid (MA2) inhibited FTO and enhanced the effect of the chemotherapy drug temozolomide on suppressing proliferation of glioma cells and negatively regulated the loop. These data collectively highlight a key regulatory circuit in glioma and provide potential targets for clinical treatment.

Significance:

These findings elucidate a novel feedback loop that regulates proliferation in glioma and can be targeted via inhibition of FTO to enhance the efficacy of temozolomide.
Tetralogy of Fallot and Outlet Ventricular Septal Defect with Anterior Malalignment Detected at Early Fetal Echocardiography
Authors: De Robertis Valentina , Persico Nicola , Volpe Grazia , Rembouskos Georgios , Fabietti Isabella , Olivieri Claudiana , Giudicepietro Antonia , Volpe Paolo
Published: July 2020

Objectives: To examine the evolution of tetralogy of Fallot (TOF) and outlet ventricular septal defect (VSD) with anterior malalignment (am) from the initial diagnosis at early fetal echocardiography through the gestation and to evaluate the impact of the first-trimester scan on the outcome. Methods: We identified cases of TOF or outlet VSD with am diagnosed before 16 weeks’ gestation. For all cases, prenatal data and pregnancy outcomes were evaluated. In continuing pregnancies, the evolution in severity of the disease was assessed. Results: Fifty-one fetuses with TOF or outlet VSD with am were diagnosed at early fetal echocardiography. Parents opted for termination of pregnancy in all 23 cases associated with additional anomalies. In 2 of 28 continuing pregnancies, there was an intrauterine death. In the remaining 26, there was progression in severity in 7 (by 20–22 weeks in 3 cases and during the third trimester in the remaining 4). Conclusions: TOF and outlet VSD with am diagnosed before 16 weeks’ gestation can progress in severity throughout pregnancy in over one-quarter of cases. In addition, a high proportion of cases diagnosed in the first trimester may have associated extracardiac anomalies, with a significant impact on clinical management and on the rate of early termination of pregnancy.
Evidence of Rubus Yellow Net Virus Integration into the Red Raspberry Genome
Authors: Diaz-Lara Alfredo , Mosier Nola J. , Stevens Kristian , Keller Karen E. , Martin Robert R.
Published: July 2020

Rubus yellow net virus (RYNV) infects Rubus spp., causing a severe decline when present in mixed infections with other viruses. RYNV belongs to the family Caulimoviridae, also known as plant pararetroviruses, which can exist as episomal or integrated elements (endogenous). Most of integrated pararetroviruses are noninfectious; however, a few cases have been reported where they excised from the plant genome and formed infectious particles. Graft transmission onto indicator plants R. occidentalis “Munger” has been the standard test method for RYNV detection in certification programs. Previously, it was noticed that some RYNV PCR-positive plants did not induce symptoms on “Munger”, suggesting an integration event. In this study, bio-indexing and different molecular techniques were employed to differentiate between integrated and episomal RYNV sequences. Reverse transcription-PCR using RYNV-specific oligonucleotides after DNase treatment generated positive results for the virus in graft transmissible isolates (episomal) only. To confirm these results, rolling circle amplification on DNA preparations from the same samples resulted in amplicons identified as RYNV only from plants with graft transmissible RYNV. High-throughput sequencing was used to identify the RYNV-like sequences present in the host DNA. These results indicate the integration of RYNV into the red raspberry genome and highlight the necessity to recognize this phenomenon (integration) in future Rubus quarantine and certification programs.
Apoyo social familiar para el bienestar de hijos gays e hijas lesbianas
Authors: Orcasita Linda Teresa , Sevilla Teresita María , Acevedo-Velasco Victoria Eugenia , Montenegro Céspedes José Luis , Tamayo María Camila , Rueda-Toro Juan Sebastián
Published: July 2020

Este artículo presenta una revisión sobre los procesos de revelación y aceptación de la orientación sexual y el papel del apoyo social familiar como un aspecto fundamental para el bienestar de hijos gays e hijas lesbianas. Se resalta que los padres, madres, hijos e hijas atraviesan diferentes etapas para lograr la aceptación de la orientación homosexual. Así mismo, el apoyo informacional permite el apoyo emocional por parte de los padres y madres. Se evidencia que ciertas creencias, estereotipos e información insuficiente, así como la pobre educación acerca de la orientación homosexual obstaculizan el apoyo social brindado por las familias a sus hijos e hijas. Se recomienda para futuras investigaciones el abordaje del apoyo social familiar, entendido como un proceso transversal, presente y activo en las familias con hijos gays e hijas lesbianas.
Effects of robotic intervention associated with conventional therapy on gait speed and resistance and trunk control in stroke patients
Authors: Siegle Cristhina Bonilha Huster , Carvalho Joyce Karoline Friosi de , Utiyama Daniela Mitiyo Odagiri , Matheus Denise , Alfieri Fabio Marcon , Ayres Denise Vianna Machado , Castro Pedro Claudio Gonsales de , Battistella Linamara Rizzo
Published: July 2020

Objective: To verify the effects of gait and robotic stair training with G-EO System, associated with conventional rehabilitation, on gait speed and endurance and trunk control of stroke participants. Methods: Retrospective study with 28 participants in the chronic phase of the disease. G-EO System was used for gait and stair robotic intervention. 20-session protocol of 20 minutes associated with conventional multidisciplinary therapy. The 10-meter Walk Test (10mWT), 6-minute Walk Test (6MWT) and Trunk Impairment Scale (TIS) tools were used. P values <0.05 were considered statistically significant with Wilcoxon test before and after intervention. Results: Significant differences found in the tests. TIS presented initial mean value of 14.29 (± 5.30) and final value of 17.04 (± 4.49), with p = 0.00044. 10mWT presented average initial velocity of 0.498 m/s (± 0.27) and final velocity of 0.597 m/s (± 0.32), p = 0.00008. 6mWT presented mean initial value of 155.89m (± 85.96) and final value of 195.39m (± 109.78), p = 0.00152. Conclusion: Gait and stair robotic therapy, associated with conventional therapy, was effective in promoting increased speed, endurance aptitude for greater gait distances and trunk control in individuals with chronic stroke after stroke.
Rastreamento de câncer em mulheres deficientes
Authors: Boer Renata , Gozzo Thais De Oliveira
Published: July 2020

Para tentar reduzir a morbidade e mortalidade por câncer, têm sido utilizadas estratégias de diagnóstico precoce e de rastreamento da doença. Para que as ações de rastreamento sejam eficazes, devem ser disponibilizadas a toda população. Entretanto não é essa a realidade de mulheres com deficiência. Objetivo: Identificar como tem sido realizado o rastreamento de câncer em mulheres com deficiência. Método: Foi realizada uma revisão integrativa da literatura com buscas realizadas nas bases de dados Pubmed, LILACS e Web of Science. Resultados: Foram incluídos 25 artigos, e pode-se observar que mulheres com deficiência apresentaram barreiras para o acesso aos serviços de saúde: escolaridade, renda, nível de incapacidade, estado civil, estar inserido em sistema de saúde privado, idade, ter um cuidador, falta de adaptação dos serviços para pessoas com deficiência e falta de conhecimento dos profissionais e das próprias mulheres. Como consequência dessas barreias, as mulheres com deficiência apresentam menor probabilidade de realizarem os exames de rastreamento. Conclusão: As mulheres com deficiência são menos propensas a comporem os programas de rastreamento do câncer de mama e colo do útero, mesmo entre países desenvolvidos.
Outcome of Flow-Gradient Patterns of Aortic Stenosis After Aortic Valve Replacement
Authors: Salaun Erwan , Clavel Marie-Annick , Hahn Rebecca T. , Jaber Wael A. , Asch Federico M. , Rodriguez Leonardo , Weissman Neil J. , Gertz Zachary M. , Herrmann Howard C. , Dahou Abdellaziz , Annabi Mohamed-Salah , Toubal Oumhani , Bernier Mathieu , Beaudoin Jonathan , Leipsic Jonathon , Blanke Philipp , Ridard Carine , Ong Géraldine , Rodés-Cabau Josep , Webb John G. , Zhang Yiran , Alu Maria C. , Douglas Pamela S. , Makkar Raj , Miller D. Craig , Lindman Brian R. , Thourani Vinod H. , Leon Martin B. , Pibarot Philippe
Published: July 2020

Background:

Although aortic valve replacement is associated with a major benefit in high-gradient (HG) severe aortic stenosis (AS), the results in low-gradient (LG, mean gradient <40 mm Hg) AS are conflicting. LG severe AS may be subdivided in classical low-flow (left ventricular ejection fraction <50%) and LG (CLF-LG); paradoxical low-flow (left ventricular ejection fraction ≥50% but stroke volume index <35 mL/m
2
) and LG; and normal-flow (left ventricular ejection fraction ≥50% and stroke volume index ≥35 mL/m
2
) and LG. The primary objective is to determine in the PARTNER 2 trial (The Placement of Aortic Transcatheter Valves) and registry the outcomes after aortic valve replacement of the 4 flow-gradient groups.

Methods:

A total of 3511 patients from the PARTNER 2 Cohort A randomized trial (n=1910) and SAPIEN 3 registry (n=1601) were included. The flow-gradient pattern was determined at baseline transthoracic echocardiography and classified as follows: (1) HG; (2) CLF-LG; (3) paradoxical low-flow-LG; and (4) normal-flow-LG. The primary end point for this analysis was the composite of (1) death; (2) rehospitalization for heart failure symptoms and valve prosthesis complication; or (3) stroke.

Results:

The distribution was HG, 2229 patients (63.5%); CLF-LG, 689 patients (19.6%); paradoxical low-flow-LG, 247 patients (7.0%); and normal-flow-LG, 346 patients (9.9%). The 2-year rate of primary end point was higher in CLF-LG (38.8%) versus HG: 31.8% (
P
=0.002) and normal-flow-LG: 32.1% (
P
=0.05) but was not statistically different from paradoxical low-flow-LG: 33.6% (
P
=0.18). There was no significant difference in the 2-year rates of clinical events between transcatheter aortic valve replacement versus surgical aortic valve replacement in the whole cohort and within each flow-gradient group.

Conclusions:

The LG AS pattern was highly prevalent (36.5%) in the PARTNER 2 trial and registry. CLF-LG was the most common pattern of LG AS and was associated with higher rates of death, rehospitalization, or stroke at 2 years compared with the HG group. Clinical outcomes were as good in the LG AS groups with preserved left ventricular ejection fraction compared with the HG group.
Use of scalation landmarks in geometric morphometrics of squamate reptiles: a comment on homology
Authors: MEIK JESSE M. , LAWING A. MICHELLE , WATSON JESSICA A.
Published: July 2020

Geometric morphometrics (GM) is a powerful analytical approach for evaluating phenotypic variation relevant to taxonomy and systematics, and as with any statistical methodology, requires adherence to fundamental assumptions for inferences to be strictly valid. An important consideration for GM is how landmark configurations, which represent sets of anatomical loci for evaluating shape variation through Cartesian coordinates, relate to underlying homology (Zelditch et al. 1995; Polly 2008). Perhaps more so than with traditional morphometrics, anatomical homology is a crucial assumption for GM because of the mathematical and biological interpretations associated with shape change depicted by deformation grids, such as the thin plate spline (Klingenberg 2008; Zelditch et al. 2012). GM approaches are often used to analyze shapes or outlines of structures, which are not necessarily related to common ancestry, and in this respect GM approaches that use linear semi-landmarks and related methods are particularly amenable to evaluating primary homology, or raw similarity between structures (De Pinna 1991; Palci & Lee 2019). This relaxed interpretation of homology that focuses more on recognizable and repeatable landmarks is defensible so long as authors are clear regarding the purpose of the analyses and in defining their landmark configurations (Palci & Lee 2019). Secondary homology, or similarity due to common ancestry, can also be represented with GM methods and is often assumed to be reflected in fixed Type 1 (juxtaposition of tissues) or Type 2 (self-evident geometry) landmarks (Bookstein 1991).
A new species of Characidium Reinhardt (Characiformes: Crenuchidae) with a unique mid-water behavior from the upper rio Madeira basin, Brazil
Authors: FLAUSINO NELSON JUNIOR , LIMA FLÁVIO C.T. , MACHADO FRANCISCO A. , MELO MARCELO R.S.
Published: July 2020

A new species of Characidium is described from headwater tributaries of the upper rio Guaporé, Rio Madeira basin, Mato Grosso state, Brazil. The new species can be diagnosed from all congeners, except Characidium summus, for lacking the preorbital and postorbital stripes. It can be diagnosed from the latter species by having 12 circumpeduncular scales (vs. 14), by an adipose fin present (vs. adipose fin absent), and 10–12 bars along the body (vs. absence of bars), among other characters. The new species is so far only known from direct tributaries of the Rio Guaporé at the Serra da Borda, an isolated plateau 300–800 meters above sea level, and possess a behavior very uncommon within the genus, being a mid-water pelagic fish, instead of the benthic behavior of most congeners. Comments on the putative phylogenetic relationships of the new species, as well as some remarks on its unusual behavior within the genus, are presented.
6. Decency, Health, and Grace Endangered by Quick Dancing?
Authors: Gremlicová Dorota
Published: July 2020

Through a contemporary newspaper article written about the question of quick dancing, this essay offers a detailed analysis of the text, the authors, their background and the cultural and political climate they represent. In Czech historiography, the period of the 1830s is understood as a time of

social and cultural change. This chapter explores how the emerging ideas regarding liberty and human rights, and a generally more accepting cultural scene are reflected in the discussion of the Redowa, a dance with Slavic roots and some Mazurka-type characteristics. The study of the reception of the Redowa in the Czech Republic allows a glimpse into the broader social and political context of the time.
12. The Ban on Round Dances 1917–1957
Authors: Bakka Egil
Published: July 2020

This chapter explores the context and reasoning behind the banning of round dances by one of Norway’s largest youth movements for about forty years from 1917. It provides portraits of the three largest popular movements in Norway, which were the main agents in relation to popular dance because they controlled most of the community houses in the country, and which all had conflicting attitudes towards social dancing and dealt with it in different ways. From the Liberal Youth Movement, which imposed the ban, to the Labour Movement, which paid little attention to the dances, this chapter examines the social, political, and religious factors that influenced these movements’ relationships to round dances.
Rainfall Kinetic Energy in Denmark: Relationship with Drop Size, Wind Speed, and Rain Rate
Authors: Tilg Anna-Maria , Vejen Flemming , Hasager Charlotte Bay , Nielsen Morten
Published: July 2020

Rainfall kinetic energy is an important parameter to estimate erosion potential in connection to soil erosion or in the recent years to the erosion of the leading edges of wind turbine blades. Little is known about the seasonal drop size distribution and fall velocity dependence of rainfall kinetic energy as well as its relationship with wind speed. Therefore, 6 years of Thies Laser Precipitation Monitor disdrometer and wind measurements from Voulund, a field site in western Denmark, were analyzed. It was found that the rainfall kinetic energy was highest in summer due to higher drop concentrations and in autumn due to more time with rain. The rainfall kinetic energy peaked for drop diameters between 0.875 and 2.25 mm independent of the season. Rainfall kinetic energy decreased significantly with increasing wind speed, if considering the vertical fall speed of the drops for the calculation of the rainfall kinetic energy. However, it should be noted that the measurement uncertainty increases with increasing wind speed. As disdrometer observations are rarer than rain rate observations, the performance of empirical equations describing the relationship between rainfall kinetic energy rate and rain rate was investigated. It was found that an equation trained with an alternative method fulfilled the statistical requirements for linear regression and had a similar error compared to equations in the literature. Based on the analyses, it can be concluded that the erosion potential due to rainfall kinetic energy is highest between June and November at low wind speeds and high rain rates.
Disentangling Item and Testing Effects in Inoculation Research on Online Misinformation: Solomon Revisited
Authors: Roozenbeek Jon , Maertens Rakoen , McClanahan William , van der Linden Sander
Published: July 2020

Online misinformation is a pervasive global problem. In response, psychologists have recently explored the theory of psychological inoculation: If people are preemptively exposed to a weakened version of a misinformation technique, they can build up cognitive resistance. This study addresses two unanswered methodological questions about a widely adopted online “fake news” inoculation game, Bad News. First, research in this area has often looked at pre- and post-intervention difference scores for the same items, which may imply that any observed effects are specific to the survey items themselves (item effects). Second, it is possible that using a pretest influences the outcome variable of interest, or that the pretest may interact with the intervention (testing effects). We investigate both item and testing effects in two online studies (total N = 2,159) using the Bad News game. For the item effect, we examine if inoculation effects are still observed when different items are used in the pre- and posttest. To examine the testing effect, we use a Solomon’s Three Group Design. We find that inoculation interventions are somewhat influenced by item effects, and not by testing effects. We show that inoculation interventions are effective at improving people’s ability to spot misinformation techniques and that the Bad News game does not make people more skeptical of real news. We discuss the larger relevance of these findings for evaluating real-world psychological interventions.
Quality of sleep and health-related quality of life among health care professionals treating patients with coronavirus disease-19
Authors: Stojanov Jelena , Malobabic Marina , Stanojevic Goran , Stevic Milos , Milosevic Vuk , Stojanov Aleksandar
Published: July 2020

Background:

Health care professionals exposed to coronavirus disease 2019 (COVID-19) are facing high levels of stress.

Aim:

The aim was to evaluate the quality of sleep (QoS) and health-related quality of life (HRQoL), among health care professionals treating patients with COVID-19, as well as quantifying the magnitude of symptoms of depression and levels of anxiety.

Methods:

We included 201 health care professionals in a cross-sectional, web-based study by applying 7-item Generalized Anxiety Disorder (GAD-7) Scale, Zung Self-rating Depression Scale, 36-item Health Survey of the Medical Outcomes Study Short Form (SF36), Pittsburgh Sleep Quality Index (PSQI) and additional survey constructed for the purpose of the study.

Results:

Health care workers who treated COVID-19 patients were more afraid of becoming infected or of transmitting the infection to a family member with a significantly low self-assessment of their mental status. Poor QoS and HRQoL correlated with high health anxiety and severe depressive symptoms and several demographic characteristics. Multiple linear regression analysis showed that higher scores on GAD-7 (beta = .71, p < .01) and lower scores on mental health (MH) subscale on SF36 questionnaire (beta = –.69; p < .01) were independent predictors of the higher PSQI score (adjusted R2 = .61, p < .01 for overall model). Higher scores on GAD-7 (beta = .68, p < .01) and worse self-perceived mental status (beta = .25; p < .05) were independent predictors of the lower SF36 scores (adjusted R2 = .73, p < .01 for overall model).

Conclusion:

The major MH burden of health care professionals treating infected patients during the COVID-19 pandemic indicates that they need psychological support.
Self-Perception and Relative Increases in Substance Use Problems in Early Adulthood
Authors: Yan Florence , Costello Meghan , Allen Joseph
Published: July 2020

This study assessed self-perception as a long-term predictor of relative changes in problems related to alcohol and marijuana use in early adulthood. Self-report questionnaires were completed by a community sample of 124 individuals in the Southeastern United States who were followed longitudinally from age 19 to 27. More problems due to substance use at age 27 were predicted by participants’ negative perceptions of their social acceptance, romantic appeal, and self-worth. Predictions remained after accounting for potential confounds including gender, income, and baseline substance use problems at age 19. Social avoidance and distress in new situations at age 19 mediated the relationship between self-perception and relative changes in substance use problems, such that increases in substance use problems from age 19 to 27 were potentially explainable by the linkage of negative self-perceptions to social avoidance and distress in new situations.
What Is Driving the Drug Overdose Epidemic in the United States?
Authors: Thombs Ryan P. , Thombs Dennis L. , Jorgenson Andrew K. , Harris Braswell Taylor
Published: July 2020

The demand-side perspective argues that the drug overdose epidemic is a consequence of changes in the economy that leave behind working-class people who lack a college education. In contrast, the supply-side perspective maintains that the epidemic is primarily due to changes in the licit and illicit drug environment, whereas a third, distinct perspective argues that income inequality is likely a key driver of the epidemic. To evaluate these competing perspectives, we use a two-level random intercept model and U.S. state-level data from 2006 to 2017. Contrary to the demand-side approach, we find that educational attainment is not associated with drug-related mortality. In support of the supply-side approach, we provide evidence indicating that opioid prescription rates are positively associated with drug-related mortality. We also find that income inequality is a key driver of the epidemic, particularly the lack of resources going to the bottom 20% of earners. We conclude by arguing that considerations of income inequality are an important way to link the arguments made by the demand-side and the supply-side perspectives.
Everyday Solidarity: A Framework for Integrating Theological Ethics and Ordinary Life
Authors: Kelly Conor M.
Published: July 2020

As moral theology responds to the pastoral emphases of Pope Francis’s pontificate, more work must be done to facilitate the integration of theological ethics and ordinary life. In order to pursue this goal in a consistent fashion, this article proposes a new form of “everyday solidarity” as a framework for linking Catholic theological convictions with everyday moral choices. The article clarifies the often-ambiguous notion of solidarity found in Catholic social teaching and describes how the new species of everyday solidarity can function as both a principle and a virtue to transform discernment in ordinary life.