bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-Fuel Power Plant as A Element of Back-Up Energy Supply of Farming Facilities
Authors: Korotkov Aleksandr , Palichyn Andrey , Savinykh Petr , Romaniuk Wacław , Borek Kinga , Barwicki Jan
Published: May 2019

Paper presents research concerned utilization of natural gas in a liquid state as a new source of electrical energy generation in country side areas of Russia to use it in a small family farms and bigger agriculture enterprises. The experiment shows that alcohol and gasoline are more expensive products to be a source for electricity generation as a reserve energy supply in agriculture production areas of the country. Introduction of natural gas generator as an alternative fuel makes possible to produce low cost of electrical energy in any part of the country, what gives great potential to alternative energy supply, but especially for agriculture production on small households and also bigger enterprises
Optimisation of Osmotic Dehydration of Plums
Authors: Ponjičan Ondrej , Sedlar Aleksandar , Findura Pavol , Szparaga Agnieszka , Kocira Sławomir
Published: May 2019

The paper presents kinetics of osmotic dehydration of plums in relation to the treatment time and concentration of sucrose solution. The main aim of the study was polyoptimisation of the preservation process, namely selection of optimal parameters of osmotic dehydration processes including changes in selected quality indicators. Defining of optimal conditions of the entire course of preservation may influence limitation of consumption of preserving substances (osmotic substances) and reduction of the energy demand. Based on the research which was carried out, it was found that parameters of osmotic dehydration had a significant impact on mass transfer coefficients and physico-chemical indicators of fruit - along with the increase of concentration of osmotic solution and extension of the time of the process, the increase of the investigated sizes was observed. In the second part of the paper, optimization of the fruit preservation process was performed. The idea of the objective function consisted in minimization of the difference between the expected values of criteria and the values obtained from the experimental results. For the defined scalar optimization criterion an explicit relation between quality and cost of the product was showed.
Systematic design of microscope objectives. Part I: System review and analysis
Authors: Zhang Yueqian , Gross Herbert
Published: May 2019

In the three connected papers, a systematic analysis and synthesis approach for microscope objectives is introduced. To subtract off the hidden assumptions in the historical development of the microscope objective lenses and extract the intrinsic lens modules, a large objective database is implemented including most of the patented systems for standardised applications. Based on the systematic analysis of the database, in Part I, a general review of the development history is given. A systematic classification method is proposed with respect to the five most significant parameters. According to the review and classification, the impacts of applications, manufacture and technology considerations are systematically analysed and summarised. Details of the lens modules will be discussed in Part II, and the synthesis approach utilising the lens modules will be introduced in Part III.
A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type I procollagen (PINP): a report from the IFCC-IOF Joint Committee for Bone Metabolism
Authors: Cavalier Etienne , Eastell Richard , Rye Jørgensen Niklas , Makris Konstantinos , Tournis Symeon , Vasikaran Samuel , Kanis John A. , Cooper Cyrus , Pottel Hans , Morris Howard A.
Published: May 2019

Background

Biochemical bone turnover markers (BTM) are useful tools to assess bone remodeling at the cellular level. N-terminal propeptide of type I procollagen (PINP) has been recommended as a reference marker for bone formation in research studies.

Methods

We describe the results of a multicenter study for routine clinical laboratory assays for PINP in serum and plasma. Four centers (Athens, Greece [GR], Copenhagen, Denmark [DK], Liege, Belgium [BE] and Sheffield, United Kingdom [UK]) collected serum and plasma (EDTA) samples from 796 patients presenting to osteoporosis clinics. Specimens were analyzed in duplicate with each of the available routine clinical laboratory methods according to the manufacturers’ instructions. Passing-Bablok regressions, Bland-Altman plots, V-shape evaluation method and the concordance correlation coefficient for PINP values between serum and plasma specimens and between methods were used to determine the agreement between results. A generalized linear model was employed to identify possible variables that affected the relationship between the methods.

Results

We showed that both EDTA plasma and serum were suitable for PINP determination. We observed a significant proportional bias between Orion radioimmunoassay and the automated methods for PINP (Roche Cobas and IDS iSYS), which both gave very similar results. The multivariate model did not improve the excellent correlation that was observed between the methods.

Conclusions

Harmonization of PINP assays is possible by applying a correction factor or correctly assigning the values of the calibrators. This work will benefit from further collaboration between assays manufacturers and clinical laboratory professionals.
Trueness assessment of HbA1c routine assays: are processed EQA materials up to the job?
Authors: Delatour Vincent , Clouet-Foraison Noémie , Jaisson Stéphane , Kaiser Patricia , Gillery Philippe
Published: May 2019

Background

With the worldwide increase of diabetes mellitus prevalence, ensuring that HbA1c assays are accurate is essential. External quality assessment (EQA) programs enable laboratories to verify that analytical methods perform according to the manufacturers’ specifications. However, assessing trueness requires commutable materials, a property that is rarely characterized for EQA materials.

Methods

The difference in bias approach was used to assess commutability of 26 processed quality control materials for 17 of the most frequently used HbA1c assays. Involved assays included immuno-assays, enzymatic assays, affinity, ion-exchange HPLC boronate affinity HPLC and capillary electrophoresis. The measurements were performed at manufacturers or expert laboratories. Assay trueness was additionally assessed against the IFCC reference measurement procedure using fresh clinical specimens that were distributed to 450 medical laboratories.

Results

Commutability of processed EQA materials was highly heterogeneous and globally insufficient to rigorously assess the trueness of HbA1c assays. Using fresh clinical specimens, mean bias was −0.13 mmol/mol for low HbA1c (34 mmol/mol), between +1.0 and +1.3 mmol/mol for intermediate HbA1c (49 and 58 mmol/mol) and +1.2 mmol/mol for elevated HbA1c (90 mmol/mol).

Conclusions

This study demonstrates that due to insufficient commutability, most processed EQA materials are unsuitable to assess trueness of HbA1c assays and agreement between the different assays. These materials can only provide information on comparability of individual laboratory results with its peers and on assay precision. Using fresh whole blood samples, this study additionally shows that most HbA1c assays are fairly accurate and meet the total allowable error quality target of 5 mmol/mol.
An innovative method for the chemical modification of Carpinus betulus wood: a methodology and approach study
Authors: Bari Ehsan , Jamali Ali , Nazarnezhad Nouredin , Nicholas Darrel D. , Humar Miha , Najafian Mohammad
Published: May 2019

The objective of this research was to evaluate the influence of acetyl and methyl bonds on the physical, mechanical, photochemical and biological resistance properties of hornbeam wood. Carpinus betulus (hornbeam) wood is considered to be a less valuable species due to poor durability. In order to improve its properties, a novel and simple method was applied to modify wood samples. Hence, wood samples were modified by either acetylation or methylation at four treatment levels. Reactions between hornbeam wood and the formalin and acetic acid treatment system were successful as exemplified by increased mass [weight percent gain (WPG)], slightly better compression strength and considerably improved impact bending strength. Furthermore, the biological decay resistance of the treated wood samples increased for all of the treatments.
The Repulsive Other in Tim Crouch’sI, Malvolio(2010)
Authors: Ablett Sarah J.
Published: May 2019

Donald Trump famously used Hillary Clinton’s ‘toilet business’ or Marco Rubio’s ‘sweating like a pig’ as talking points in his campaign for the U. S. presidency. He thereby managed to use disgust’s intrinsic link to fear as a catalyst to negatively influence people’s opinion of his opponents. It was a tactic he also successfully used to rally his supporters against groups of people like ‘lying’ journalists or ‘rapist’ Mexicans. The mechanism of dehumanising the Other via association with disgust can be regarded as a dangerous tool of political rhetoric. In times like ours, where political discourse is commonly drenched in emotional hyperbole, it is paramount that we come to understand our emotions and learn how easily they may be hijacked for political purposes; this is especially true for such a seemingly ‘intuitive’ emotion as disgust. In his playI, Malvoliodramatist Tim Crouch gives voice to a Shakespearean character who has become a victim of discrimination via disgust. Crouch turns the perspectives around and allows the audience to see the story from the deplored’s point of view. This paper uses Crouch’s play for an exemplary analysis of the underlying structures of repulsion, and its relation to fear, and investigates the aesthetic possibilities of redemption.
Terror by Candlelight: The Affective Politics of Fear in Tanika Gupta’sLions and Tigers
Authors: Tronicke Marlena
Published: May 2019

In 2017, Tanika Gupta’sLions and Tigerspremiered at London’s candle-lit, neo-Jacobean Sam Wanamaker Playhouse, which, at first glance, seems ill suited to house a play which is set in pre-Partition Bengal and which depicts both rioting mobs and machine gun shootings. This essay looks at the ways in which, contrary to such initial associations, text and performance space supplement each other. In this case, supposedly cosy candlelight and close proximity to the audience engender feelings of fear and anxiety that can be framed with Sara Ahmed’s notion of the ‘affective politics of fear.’ Continuously interwoven with negotiations between the leading figures of the Indian National Congress, Gupta’s play is firmly set in its own historical context. On the other hand, its climate of boiling nationalism and close parallels tojihadmake it equally relevant to the present day. It is because of this contemporaneous historicity that Gupta’s play proves so gripping: through their ostensibly homely seventeenth-century staging, terror and political unrest become all too close to home, and soLions and Tigersis as much a play that uncovers the hidden stories of Indian Partition as it speaks to the here and now.
(Play)Houses of Horror: Addressing the Anxieties of the Housing Crisis
Authors: Birke Dorothee
Published: May 2019

Among the fears rife in contemporary “Insecure Britain”,

This was a header used by the Guardian for a series of articles in 2014, which described a growing sense of social precarity and disillusionment with mainstream politics in Britain: https://www.theguardian.com/society/series/insecure-britain

the anxieties connected with the housing crisis – rise of property costs, cutbacks on welfare housing, increasing precarity of living conditions – may be among the most tangible in everyday life. It is not surprising, then, that the disruptive power of threats to home as a source of security and comfort has been at the centre of a series of recent British plays. While many of these are marked by documentary realism, incorporating real-life testimonies in order to evoke empathy with those hit hardest by the crisis, there is also a notable subset that veer to the other side of the sur/realist spectrum, reflecting on the crisis in highly stylized dystopian scenarios.

In this article, I propose the concept of ‘playhouse Gothic’ to describe Mike Bartlett’s Game and Philip Ridley’s Radiant Vermin (both 2015). Both are explorations of the affective and social implications of the housing crisis that fall into the latter category. The case studies examine how in both plays the interplay between dramatic and theatrical space foregrounds the extent to which our homes themselves are sources of insecurity. More specifically, the plays employ the mode of the Gothic in order to involve their audiences in an emotionally loaded spatial experience, thereby also inviting them to reflect on their own socio-economic anxieties and implication in perpetuating structures of inequality. The analyses take into account the dramatic texts and the set-up of concrete performances as well as reviews documenting viewers’ responses to the plays.
FeArt and Dance-xiety in Nature Theater of Oklahoma’s Pursuit of Happiness: Artificiality, Authenticity and Fun as the Building Stones of a Hopeful Performative
Authors: Lacko Ivan
Published: May 2019

Pursuit of Happinessis a 2017 co-production of the American group Nature Theater of Oklahoma and the Slovenia-based, multinational En-Knap dance company. The genre-defying production provocatively misleads the audience through the textual as well as performative aspects of the piece. From slapstick scenes, through dynamic dance movements, all the way to philosophically challenging perceptions about the nature of our reality, the play balances on the edge of timid expressions of existentialist angst, Baudrillardian overload of simulacra, and an attempt to address a mechanical reproduction of art (and life) reminiscent of Walter Benjamin.This contribution endeavours to present an analysis of Pursuit of Happiness as an explosive contemporary piece that portrays a disintegrating world, where fear and anxiety engulf people’s lives as suddenly as the play’s formal structure breaks and changes. Following Jill Dolan’s ruminations about “hopeful performatives”, the paper seeks to plot out a set of such performatives and narratives in the selected play, and to show how they function in the liminal combination of dance and drama, movement and performance, art and life, and how these narratives can become part of what Elliot Leffler and Michael Mellas call divergent dramaturgy.
The crystal structure of a matrine derivative, 13-(4-Cl-pyrrole)-matrine, C18H26ClN4O
Authors: Jing-Min Ye , Hui-Qing He , Xu-Hong Jiang , Zhan-Mei Liu , Xing-An Cheng , Zhao-Chang He
Published: May 2019

C18H26ClN4O, orthorhombic, P212121 (no. 19), a = 5.3476(1) Å, b = 14.4068(2) Å, c = 22.3285(4) Å, V = 1720.23(5) Å3, Z = 4, R
gt(F) = 0.0328, wR
ref(F
2) = 0.0774, T = 100 K.
Synthesis and crystal structure of (±)-Ethyl 5′-(difluoromethyl)-2-oxo-4′,5′-dihydrospiro[indoline-3,3′-pyrazole]-4′-carboxylate, C14H13F2N3O3
Authors: Li Wu-Wu , Zheng Min-Yan , Guo Ying , Jiang Yan-Ping , Wang Qiao , Wang Mei , Ji Min-Xiang , Zhang Yu-Tao , Zhang Zun-Ting
Published: May 2019

C14H13F2N3O3, triclinic, P1̄ (no. 2), a = 9.4486(7) Å, b = 12.4694(8) Å, c = 13.8690(8) Å, α = 65.734(6)°, β = 74.523(5)°, γ = 83.726(6)°, V = 1435.63(18) Å3, Z = 4, Rgt
(F) = 0.0495, wR
ref(F
2) = 0.1249, T = 293(2) K.
The rare earth metal hydride tellurides REHTe (RE=Y, La–Nd, Gd–Er)
Authors: Folchnandt Matthias , Rudolph Daniel , Hoslauer Jean-Louis , Schleid Thomas
Published: May 2019

The synthesis and crystal structure of a series of rare earth metal hydride tellurides with the composition REHTe (RE = Y, La–Nd, Gd–Er) is reported. These compounds have been obtained by the reaction of rare earth metal dihydrides (REH2) with elemental tellurium in sealed tantalum capsules at T = 700°C using cesium chloride (CsCl) as fluxing agent, which can be washed away with water due to the astonishing insensitivity of these hydride tellurides (REHTe) against hydrolysis. All of the compounds crystallize in the hexagonal space group P6̅m2 with a filled WC-type crystal structure, exhibiting a mutual trigonal-prismatic coordination of the heavy ions (RE
3+ and Te2−), while the hydride anions reside in the trigonal prismatic voids surrounded by three rare earth metal cations expanding their coordination pattern to a tricapped trigonal prism. This 1H-type crystal structure is compared with the 1H- and 2H-type structures of the respective hydride selenides (REHSe, RE = Y, La–Nd, Gd–Tm, Lu). Both hexagonal basic crystal structures can be derived from the AlB2-type structure as demonstrated in a Bärnighausen tree by group-subgroup relationships.
Peter Olen: Wilfrid Sellars and the Foundations of Normativity
Authors: Legg Catherine
Published: May 2019

All contributions included in the present issue were originally prepared for an “Author Meets Critics” session organized by Carl Sachs for the Eastern Division Meeting of the American Philosophical Association in Savannah, Georgia, on 5th January, 2018.
Body Image Distortion Following Social Rejection or Acceptance Cues
Authors: Mu Wenting , Schoenleber Michelle , Leon Ariana Castro , Berenbaum Howard
Published: May 2019

Introduction: Body image has been shown to be subject to explicit, body-related feedback influences, yet little attention has been paid to subtle feedback about overall social acceptability. The current study tested competing hypotheses regarding women's body image after being primed with cued social rejection or acceptance. Whereas sociometer theory predicts that women will perceive their bodies more negatively following a social rejection prime, self-enhancement theory predicts the opposite.

Method: A total of 105 female undergraduate students underwent a conditioning procedure in which distinctive tones were paired with signs of social rejection or acceptance. After this, body distortion (measured by a participant-adjusted virtual image), self-reported body satisfaction and affect were measured, while one of the tones sounded repeatedly in the background.

Results: Compared with the acceptance condition, rejection condition participants reported greater state negative affect, F(1, 103) = 4.41, p = .04, greater state positive affect, F(1, 103) = 5.52, p = .02, and perceived their bodies as being smaller, F(1, 103) = 6.53, p = .01, consistent with the expectations of self-enhancement theory.

Discussion: Implications of these findings are discussed regarding improved understanding of body image disturbance as well as development of novel clinical treatments.
Developmental Course of Personality Disorder Traits in Childhood and Adolescence
Authors: Hamlat Elissa J. , Young Jami F. , Hankin Benjamin L.
Published: May 2019

Developmental patterns of personality pathology traits are not well delineated from childhood through late adolescence. In the present study, participants (N = 675, 56% female) were recruited to create three cohorts of third (n = 205), sixth (n = 248), and ninth (n = 222) graders to form an accelerated longitudinal cohort design. We assessed six PD (avoidant, dependent, histrionic, narcissistic, borderline, schizotypal) traits based on DSM-IV trait diagnostic conceptualizations via parent report at baseline, 18 months, and 36 months. According to parent report, mean levels of avoidant, dependent, histrionic, narcissistic, borderline, and schizotypal traits all declined for both boys and girls. The changes in dependent and histrionic traits were of medium effect size, and the changes in avoidant, narcissistic, borderline, and schizotypal traits were of small effect size. Over the 3 years of the study, the traits of each PD also demonstrated moderate to high rank-order stability.
Somatic genetic alterations in a large cohort of pediatric thyroid nodules
Authors: Pekova Barbora , Dvorakova Sarka , Sykorova Vlasta , Vacinova Gabriela , Vaclavikova Eliska , Moravcova Jitka , Katra Rami , Vlcek Petr , Sykorova Pavla , Kodetova Daniela , Vcelak Josef , Bendlova Bela
Published: May 2019

There is a rise in the incidence of thyroid nodules in pediatric patients. Most of them are benign tissues, but part of them can cause papillary thyroid cancer (PTC). The aim of this study was to detect the mutations in commonly investigated genes as well as in novel PTC-causing genes in thyroid nodules and to correlate the found mutations with clinical and pathological data. The cohort of 113 pediatric samples consisted of 30 benign lesions and 83 PTCs. DNA from samples was used for next-generation sequencing to identify mutations in the following genes: HRAS, KRAS, NRAS, BRAF, IDH1, CHEK2, PPM1D, EIF1AX, EZH1 and for capillary sequencing in case of the TERT promoter. RNA was used for real-time PCR to detect RET/PTC1 and RET/PTC3 rearrangements. Total detection rate of mutations was 5/30 in benign tissues and 35/83 in PTCs. Mutations in RAS genes (HRAS G13R, KRAS G12D, KRAS Q61R, NRAS Q61R) were detected in benign lesions and HRAS Q61R and NRAS Q61K mutations in PTCs. The RET/PTC rearrangement was identified in 18/83 of PTCs and was significantly associated with higher frequency of local and distant metastases. The BRAF V600E mutation was identified in 15/83 of PTCs and significantly correlated with higher age of patients and classical variant of PTC. Germline variants in the genes IDH1, CHEK2 and PPM1D were found. In conclusion, RET/PTC rearrangements and BRAF mutations were associated with different clinical and histopathological features of pediatric PTC. RAS mutations were detected with high frequency in patients with benign nodules; thus, our results suggest that these patients should be followed up intensively.
Reciprocal interplay of miR-497 and MALAT1 promotes tumourigenesis of adrenocortical cancer
Authors: Hassan Nunki , Zhao Jing Ting , Glover Anthony , Robinson Bruce G , Sidhu Stan B
Published: May 2019

Adrenocortical carcinoma (ACC) has high recurrence rates and poor prognosis with limited response to conventional cancer therapy. Recent contributions of high-throughput transcriptomic profiling identified microRNA-497 (miR-497) as significantly underexpressed, while lncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) as overexpressed in ACC. miR-497 is located in the chromosomal region 17p13.1, in which there is a high frequency of loss of heterozygosity in ACC. We aim to investigate the interaction of miR-497 and MALAT1 in ACC and its functional roles in the process of tumourigenesis. In this study, we demonstrated miR-497 post-transcriptionally repressed MALAT1 while MALAT1 also competes for miR-497 binding to its molecular target, EIF4E (eukaryotic translation initiation factor 4E). We showed that overexpression of miR-497 and silencing of MALAT1 suppressed cellular proliferation and induced cell cycle arrest through downregulation of EIF4E expression. Furthermore, MALAT1 directly binds to SFPQ (splicing factor proline and glutamine rich) protein, indicating its multifaceted roles in ACC pathophysiology. This is the first study to identify the feedback axis of miR-497-MALAT1/EIF4E in ACC tumourigenesis, providing novel insights into the molecular functions of noncoding RNAs in ACC.
PROTEZ KAİDE MATERYALLERİNDE FARKLI POLİSAJ YÖNTEMLERİNİN YÜZEY PÜRÜZLÜLÜĞÜ VE BAKTERİYEL KOLONİZASYON ÜZERİNE ETKİLERİNİN İNCELENMESİ
Authors: YENİSEY Murat , KÖKÇÜ Deniz
Published: May 2019

Amaç: Polimerizasyon yöntemleri farklı olan protez kaide materyallerine
uygulanan çeşitli polisaj işlemlerinin kaide materyalinin yüzey pürüzlülüğü ve bakteriyel kolonizasyonu üzerine etkilerini
incelemektir. Gereç ve Yöntemler:Çalışmada; ısıyla (Lucitone199, Paladon 65, SR Ivocap Plus), ışıkla (Versyo.comHD) ve mikrodalga (Acron MC) ile
polimerize olan protez kaide materyalleri kullanılmıştır. Tüm örnek yüzeyleri
600, 1000 ve 1200 grid’ lik silikon karbid zımparalarla zımparalanmıştır. Her bir protez kaide materyaline ait
örnekler farklı polisaj yöntemlerinin uygulandığı 4 alt gruba ayrılmıştır (n=10). Kontrol amaçlı olarak bir gruba
mekanik polisaj (M), diğer üç gruba ışıkla polimerize olan glaze likitleriyle (Palaseal,
Plaquit, Lightplast-Lack) kimyasal polisaj uygulanmıştır. Yüzey pürüzlülüğünün değerlendirilmesinde
profilometre, 1 gün ve bir ay sonrasındaki bakteriyel kolonizasyonu değerlendirmede kültürel sayım yöntemlerinden
koloni sayım yöntemi kullanılmıştır. Veriler parametrik
çift yönlü varyans analiziyle değerlendirilmiş ve ortalamaların çoklu karşılaştırılmasında Tukey HSD
testi kullanılmıştır (p=0.05). Yüzey
pürüzlülüğü ve bakteriyel
kolonizasyon arasındaki etkileşim Pearson sıra
korelasyon testi ile incelenmiştir. Bulgular:Polisaj yöntemleri karşılaştırıldığında en düşük ortalama yüzey pürüzlülük (Ra) değerleri PL ve L gruplarında elde edilmiştir. Her iki bakteriyel kolonizasyon ölçümü
sonucunda L ile diğer gruplara göre daha düşük kolonizasyon değerleri elde edilmiştirSonuçlar:Işıkla aktive olan glaze likitlerinin genel olarak
mekanik polisaja göre daha iyi sonuçlar verdikleri görülmüştür. Lightplast-Lack’in yüzey pürüzlülüğünü ve kolonizasyonu azaltmada diğer polisaj yöntemlerine alternatif olarak
kullanılabileceği tespit edilmiştir. Çalışmamızda kullanılan tüm
polisaj yöntemlerinin düzgün yüzeyler elde etmedeki etkinliği yeterli bulunmuştur.  Ancak bu materyallerle ilgili daha ileri çalışmalara ihtiyaç olduğu düşünülmektedir. Anahtar Kelimeler:mekanik polisaj, kimyasal polisaj, protez kaide akrilikleri
Salpingoovarektomija, naudojant Senhance® robotinę sistemą: klinikinis atvejis
Authors: Šiaulys Raimondas
Published: May 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]

Straipsnyje aprašoma vienpusės sapingovarektomijos operacija, naudojant Senhance® robotinę sistemą. Aptariama operacijos atlikimo technika, nurodomi privalumai, pateikiami rezultatai.
Chromosomal anomalies in dairy cattle as reasons of impaired fertility
Authors: Dzitsiuk V. , Tipilo H.
Published: May 2019

Aim. The evaluation of animals for the presence of chromosomal anomalies is one of the main tasks of prac- tical selection, aimed at detecting undesired chromosomal anomalies in early age, which may have negative impact on the reproductive and productive capability of cows and lead to considerable economic losses. The aim of the work is a cytogenetic analysis of the chromosome set in cows of Ukrainian Red-and-Motley dairy cattle breed, which will allow assuming a decrease in reproductive functions with chromosomal aberrations. Methods. We examined 53 cows of the Ukrainian Red-and-Motley dairy cattle breed in SE Research Farm Khrystynivske, IABG named after M.V. Zubets, NAAS. The investigation of chromosomal anomalies involved 72-h cultivation of lymphocytes from the peripheral blood of animals using the common methods. During a routine analysis the preparations were stained with 2 % Giemsa staining solution. The induction of G-bands for differential staining of chromosomes was conducted using 0.25 % solution
of trypsin. The processing of study results was performed with Microsoft Excel software package. Results. The investigations in the aberration spectrum detected aneuploid and polyploid cells, breaks and fragments of chromosomes, premature chromo- some disjunction in mitosis and translocation. The total number of aberrant cells in cows with decreased fertil- ity was 14.69 ± 0.56 %, the number of aberrations per one investigated cell was 0.144, which was almost twice reliably (Р < 0.999) exceeding the values of similar features for cows which did not have problems with repro- duction. GTG-banding method was used to detect a new RT 13/23 Robertsonian translocation. Conclusions. The cytogenetic analysis of chromosome set of Ukrainian Red-and-Motley dairy breed cows allows assuming the connection between a decrease in the fertility of cows and chromosomal instability. A routine screening of dairy cows allows both evaluating the karyotype saturation with undesired chromosomal aberrations and using the obtained
results to forecast the reproductive ability of an animal in the early age.
Index evaluation of pigs and determination of selection limits
Authors: Pelikh V. , Ushakova S. , Pelikh N.
Published: May 2019

Aim. To determine genetically and mathematically grounded target standards of selecting pigs for future gen- erations. To determine minimal selection limits for pigs to obtain high productivity traits. Methods. Common methods of evaluating the reproductive ability of sows, fattening and meat-fat qualities of progeny. Selection indexes were built by the method of standardized deviations according to M.V. Mykhailov. The target selec- tion limits for animals were determined using the table of Le Roy. Results. Selective-genetic parameters were determined by the main traits of reproductive ability, fattening and meat productivity of pigs. Selection indexes were estimated using the weighting coeffi cients of the traits for each group of pigs, used as a basis for minimal limits at different intensities of selection. The estimation of local progeny by selection indexes allowed ranging them depending on the level of productivity with the consideration of genotype. At 20 % selection, the minimal value of the
reproductive ability index for the control group was 238.7 points. The minimal target threshold while selecting sires by the fattening traits of progeny within the 20 % selection was from 50.57 to 255.65 points for different groups. The minimal value of the index of fattening and meat traits was in the range from 270.05 to 606.94 points. Conclusions. The index estimation of pigs during the crossing allowed ranging them by the values of indexes. Minimal limits of selecting animals were determined and the selection of parental pairs with estimated productivity was optimized: in case of 20 % selection by multiple pregnancy with at least 11 animals, the area of “loin eye” – 30.5 – 44.5 sq.cm. It would be reasonable to select the animals, the pro- ductivity of progeny of which is above the determined limit, for further breeding from 238.70 to 606.94 points.
“Bukvar Yuzhnorusskіy, 1861” by Taras Shevchenko in the communicative space of Ukraine: the reality and prospects of presence
Authors: Bucharskaya I.
Published: May 2019

This study is an attempt to determine the role of the last text of T. G. Shevchenko’s “Bukvar Yuzhnorusskіy, 1861” in the whole communicative space of Ukraine.For this purpose, study was conducted in the following areas: characteristics of the era of writing the text and its entry into the communicative space; determining the place of the text in the creative history of the author; the study of the internal structure of the text; the characteristics of modernity regarding the presence of the text in the mass consciousness.In the process of the study, the following results have been obtained: according to the information given by the press of that time and the letters of T.G. Shevchenko “Bukvar Yuzhnorusskіy, 1861” became a significant event in public life; its compilation, printing and distribution became a reality because by that time the Ukrainian literature researchers had collected and printed a certain number of folk texts, Shevchenko had his own David Psalms cycle, and the society supported the idea of creating Sunday schools by charity meetings; modern Ukrainian society does not need the “Bukvar Yuzhnorusskіy, 1881”, due to the loss of the value of the textbook for elementary school and the lack of a need for the textbook of Christian morality; the quality research “Bukvar Yuzhnorusskіy, 1861” and its separate components (David Psalmi, duma) does not affect the relevance of the text in the mass consciousness.
Quantitative methods of studying the consumer needs and behavior in the context of modern marketing communications
Authors: Demchenko M.
Published: May 2019

The factors which resulted in not only changes in basic consumers’ requirements to the goods, but also in changes in their preferences and expectations and, moreover, in their value orientations, are determined. Today, the consumer has an opportunity to choose a variety of goods on a shelf, a place of a purchase, a convenient channel of communication and also a way of life. The development of digital technologies has led to a decrease in the dependence and physical commitment of a consumer to a place of work, residence or communication channel. For a successful business marketing strategy, one needs to identify these changes quickly and reliably, analyze them, and, based on the analysis, formulate their marketing strategy, both in terms of assortment policies and in terms of marketing communications. An example of instrumental consumer research conducted by well-known brands of the FMCG segment analyzes the techniques of studying consumers’ behavior and the preferences that they give to one or another product, and the possibility of targeted influence on the adoption of relevant decisions. Problems with the reliability of data obtained by traditional methods of quantitative research are revealed. Since modern methods are extremely simplistic, they often do not take into account the peculiarities of the mentality of the consumers of a particular region, their behavioral and value settings, which determine their answers during surveys. Even with an individual approach to developing a questionnaire that takes into account the characteristics of respondents, there is no guarantee of the reliability of the data. However, management decisions are made and marketing strategies are developed being based on these data. Similar errors, typical for traditional methods of research, make it necessary to look for alternative solutions. Such an alternative would be Big Data, a tool that has already proven itself as an effective technology of sociological research during the presidential campaign of D. Trump in the United States and Brexit in the UK.
Specificity of the coverage of European integration processes in Ukraine
Authors: Tarnavska I.
Published: May 2019

The publications of the Ukrainian quality national socio-political newspapers “The Day” and “Dzerkalo Tyzhnya” for the period from 2013 till 2018 are analyzed. The main trends and peculiarities of the coverage of the European Integration Processes in Ukraine are outlined, their thematic areas and methods of the audience attention-focusing techniques are presented in the chronological order. Focusing on the specificity of the reader’s preferences in the analyzed newspapers, considering the peculiarities of the presentation of the material, the author’s preferences, the nuances of the editorial policy of each media, the monitoring of publications has been conducted over the five-year period, being based on the methods of the comparative and quantitative content analysis, which allowed for identification of certain trends and principles of the presentation of topics related to the European Integration processes of Ukraine. Thus, the change in the approaches to information and analytical support of the European Integration Processes depends on the socio-political situation. The fact that the content of the chosen quality media has been selected for the research is indicative hereof. The change in rhetoric, excessive emphasis on certain nuances, the selection of individual facts – all of these print and broadcasting media methods are permanent. The quality resources should avoid the application of such approaches. On the contrary, this study focuses on the significant drawbacks of the current media practice. The obtained results show that there is a further need in deep analysis of the current trends and situation, related to the information and analytical support of the European integration processes in Ukraine and the necessity for further search of the optimal approaches towards this thematic area.
Evaluación de la recuperación de P2O5 a través de tres modelos de flotación espumante de roca fosfórica
Authors: Bustamante-Rúa Moises Oswaldo , Daza-Aragón Alan José , Bustamante-Baena Pablo , Osorio-Botero Julian David
Published: May 2019

El objetivo fundamental de la investigación es evaluar a través de 3 modelos de flotación espumante (directa, inversa y directa-inversa) la recuperación de P2O5 en roca fosfórica. Se tomaron muestras representativas del departamento del Tolima y se establecieron parámetros para cada una de las flotaciones con un tiempo de acondicionamiento de 5 minutos y tiempos de flotación entre 7-10 minutos. Se realizaron mediciones de ángulo de contacto, encontrándose para el caso del cuarzo un valor de 39° que refleja su hidrofilicidad. De acuerdo a las mediciones de Potencial Z, se determinó que existe una región de separación entre pH 2-5,8 usando colectores aniónicos para flotación directa y pH 5,8-10 usando colectores catiónicos para flotaciones inversas de Hidroxilapatito. Finalmente, se encontró que la flotación directa-inversa permitió una mayor recuperación de P2O5, utilizando como colectores el ácido oleico y el Aero® 845 Promoter en el proceso aniónico, y el colector Aeromine® 3030C y el depresante ácido fosfórico en el proceso catiónico.
Effect of bean rust [Uromyces appendiculatus (Pers.) Strauss] on photosynthetic characteristics, superoxide-dismutase activity, and lipid peroxidation of common bean (Phaseolus vulgaris L.)
Authors: Bojtor Cs. , Győri Z. , Sipos P. , Radócz L. , Tóth B.
Published: May 2019

The aim of the study was to investigate changes of photosynthetic efficiency, amount of photosynthetic pigments, superoxide dismutase (SOD) enzyme activity, and rate of lipid peroxidation in bean-rust interaction. The clarification of the role of the above changes involved in the defence mechanism can significantly contribute to the breeding of plant varieties with natural resistance. Consequently, the amount of chemicals used in food production can be significantly reduced. In the present study some principal physiological parameters, such as the relative chlorophyll content of the host plant, the amount of photosynthetic pigments, changes in photosynthetic efficiency, and the activity of superoxide-dismutase (SOD) in addition to rate of lipid peroxidation (LP) were measured. The experiment was conducted in a humidity tent. Significant decrease in the relative chlorophyll content and in the amount of photosynthetic pigments was measured. At both sampling times, an increase was found in superoxide-dismutase enzyme activity and in rate of lipid peroxidation due to the bean rust infection. Notably, in several cases the differences were significant. The results indicate that the above parameters have important role in the bean-rust interaction, which should be taken into consideration in resistance breeding.
Physicochemical characterization of blueberry (Vaccinium spp.) juices from 55 cultivars grown in Northern Spain
Authors: Madrera R. Rodríguez , Valles B. Suárez , Negrillo A. Campa , Fernández J.J. Ferreira
Published: May 2019

Blueberry (Vaccinium spp.) cultivation has experienced a notable increase both for its good organoleptic characteristics and the nutritional and functional properties of this berry. The aim of this study was the physicochemical characterization of blueberry juices obtained from 55 blueberry cultivars grown under the same environmental conditions for 2–4 years. The results provide a broad and robust database, both for the number of cultivars and the periods of monitoring thereof, in order to cover different aspects of blueberry processing, and more specifically, production of juices. Blueberries belonging to V. virgatum cultivars showed the higher values of total anthocyanin content, total phenolic content, antioxidant activity, soluble solids, and pH, and V. corymbosum cultivars the higher level of titratable acidity. Results also showed a high variability among cultivars. Observed variations can be used in plant breeding and classification of blueberry cultivars, at least, at the species level.
Effect of temperature, time, and asparaginase on acrylamide formation and physicochemical properties of bread
Authors: Ghorbani N. Samadi , Tehrani M. Mazaheri , Khodaparast M.H. Haddad , Farhoosh R.
Published: May 2019

The aim of the current paper was to elucidate the influence of temperature and time on acrylamide formation and physico-chemical characteristics of bread. Additionally, the effect of asparaginase addition to bran was evaluated. With increasing baking time and temperature, the amount of acrylamide (µg kg−1) increased. The results indicated that the acrylamide concentration in treated samples with asparaginase was significantly less than those without asparaginase treatment. Based on Pearson’ test, it was found that there was a significant correlation between baking temperature and acrylamide concentration (R=0.99, P=0.025; and R=0.98, P=0.026 for the samples prepared by baking for 2.5 min and 3 min, respectively). The firmness of bread samples increased with increasing baking temperature (P>0.05), while asparaginase addition did not significant affect the textural characteristics of the final product. Breads baked at 320 °C for 3 min were more acceptable by the sensory panel in terms of their texture and chewiness, whereas the samples baked at 370 °C for 2.5 min had the lowest score in comparison to other evaluated samples.
β-aminobutyric acid induces disease resistance against Botrytis cinerea in grape berries by a cellular priming mechanism
Authors: Wang K.T. , Wu D.Z. , Guo D.Q. , Du M.Y.
Published: May 2019

The present study was performed to investigate the effect of β-aminobutyric acid (BABA) treatment on defence activation in grape berries and to analyse its cellular mechanism. The results implied that BABA treatment at an effective concentration of 20 mM significantly inhibited gray mould rot caused by Botrytis cinerea in grape berries by inducing resistance. Accordingly, 20 mM BABA triggered a priming defence in grape suspension cells, since only the BABA-treated cells exhibited an accelerated ability for augmenting defence responses upon the pathogen inoculation. The primed cellular reactions were related to an early H2O2 burst, prompt accumulation of stilbene phytoalexins and activation of PR genes. Thus, we assume that 20 mM BABA can induce resistance to B. cinerea infection in intact grape berries perhaps via intercellular priming defence. Moreover, the BABA-induced priming defence is verified, because no negative effects on cell growth, anthocyanin synthesis, and quality impairment in either grape cells or intact berries were observed under low pathogenic pressure.
Investigation of overall and melamine migration from melamine bowls
Authors: Manav H.M. , Gurbuz O. , Cumbul D. , Tokat I.E. , Korkmaz E. , Dagdelen A.F.
Published: May 2019

Overall and melamine migration have been determined for 60 samples of melamine resin bowls, which were purchased in various local markets in the area of Bursa, Turkey. The samples were exposed to food simulants 3% acetic acid, 10% ethanol aqueous solutions, and rectified (refined) olive oil at 100 °C for 30 min, and 50% ethanol aqueous solutions at 60 °C for 30 min. The LOQ value was calculated as 3.3 mg dm−2 for overall migration and 0.126 mg kg−1 for melamine migration. Research findings did not exceed the limit of overall migration level (10 mg dm−2). Also, melamine levels of all tested items found in the third assays were below the specific migration limit (SML) of 2.5 mg kg−1 set out in the EU 10/2011 (EU, 2011) and Turkish Food Codex 2013/34 (TFC, 2013a). Some expensive as well as cheap products showed close migration levels. The increased cost of the item did not indicate a higher quality regarding health in this study.
Magnetic Lattices for Ultracold Atoms
Authors: Tran Tien Duy , Wang Yibo , Glaetzle Alex , Whitlock Shannon , Sidorov Andrei , Hannaford Peter
Published: May 2019

This article reviews the development in our laboratory of magnetic lattices comprising periodic arrays of magnetic microtraps created by patterned magnetic films to trap periodic arrays of ultracold atoms. Recent achievements include the realisation of multiple Bose-Einstein condensates in a 10 \(\mu\)m-period one-dimensional magnetic lattice; the fabrication of sub-micron-period square and triangular magnetic lattice structures suitable for quantum tunnelling experiments; the trapping of ultracold atoms in a sub-micron-period triangular magnetic lattice; and a proposal to use long-range interacting Rydberg atoms to achieve spin-spin interactions between sites in a large-spacing magnetic lattice.
AVRUPA BİRLİĞİ’NE ÜYELİK SÜRECİNDE TÜRKİYE VE BATI BALKAN ÜLKELERİNİN EKONOMİK VE MALİ PERFORMANSI: KÜRESEL KRİZ SONRASI BİR DEĞERLENDİRME
Authors: SERBES Halil , TOKATLIOĞLU Mircan
Published: May 2019

Bu çalışma, Avrupa Birliği’ne üyelik sürecinde olan Türkiye ile Batı Balkan ülkelerinin küresel kriz sonrası ekonomik ve mali performanslarının karşılaştırılmasını amaçlamaktadır. Türkiye ve Batı Balkan ülkeleri (Makedonya, Karadağ, Sırbistan, Arnavutluk aday ülkeler; Kosova ve Bosna Hersek potansiyel aday ülkelerdir), Avrupa Birliği’nin ekonomik ve mali uyuma ilişkin kriterlerini yerine getirmekle yükümlüdürler. Küresel kriz ve ardından yaşanan borç krizi Avrupa Birliği’ne üye ülkeler kadar aday Batı Balkan ülkelerinin ekonomik ve mali performanslarını ciddi biçimde etkilediğinden, Batı Balkan ülkeleri müzakere sürecindeki yükümlülüklerini yerine getirmede zorlanmaktadırlar. 2008-2016 yıllarına ilişkin reel gayri safi yurtiçi hasıla, işsizlik, enflasyon, kamu açığı, kamu borcu, kamu gelirleri ve harcamaları gibi ekonomik ve mali göstergeler bu durumu açıkça ortaya koymaktadır. Batı Balkan ülkelerine göre küresel krizden daha sınırlı düzeyde etkilenen Türkiye ise dikkate alınan göstergeler bakımından daha olumlu bir görünüm sergilemesine rağmen, Avrupa Birliği, üyelik bakımından Batı Balkan ülkelerine daha yakın dururken, Türkiye ile arasına daha fazla mesafe koymaktadır.
MYCOBACTERİUM TUBERCULOSİS KOMPLEKSİ KLİNİK İZOLATLARINDA İZONİAZİD VE RİFAMPİSİN DİRENCİNİN HIZLI TANISI İÇİN ‘REVERSE BLOT HYBRIDIZATION ASSAY MYCOBACTERIUM TUBERCULOSIS DRUG RESISTANCE’ YÖNTEMİNİN ETKİNLİĞİNİN ARAŞTIRILMASI
Authors: ÖZTÜRK Tuba , ARIDOĞAN Buket , SESLİ ÇETİN Emel
Published: May 2019

Amaç: Dirençli Mycobacterium
tuberculosis kompleksi klinik izolatlarının hızlı tespiti, erken ve uygun
tedavinin planlanmasında en önemli basamaktır. REBA MTB-MDR, klinik izolatlarda
rpoB, katG, inhA, ahpC gen
mutasyonlarının hızlı tespiti için tasarlanan ve ticari olarak temin edilen
reverse blot hibridizasyon esaslı bir DNA strip testidir. Bu çalışmanın amacı M. tuberculosis kompleksi klinik
izolatlarında izoniazid (INH) ve rifampisin (RIF) direnci ile ilişkili mutasyon
tiplerinin REBA MTB-MDR testi ile belirlenmesi ve testin tanısal performansının
BACTEC MGIT 960 ile karşılaştırılmasıdır.

Gereç ve Yöntem:
Çalışma, 2008-2013 yılları arasında Süleyman Demirel Üniversitesi Tıp Fakültesi
Mikrobiyoloji laboratuvarında çeşitli klinik örneklerden izole edilen 55 M.
tuberculosis
kompleks suşu ile yapıldı. Suşların primer anti tüberküloz ilaç duyarlılıkları  BACTEC MGIT 960 sistemiyle belirlendikten
sonra INH ve RIF direnci gen mutasyonları REBA MTB-MDR testi ile araştırıldı.

Bulgular: Çalışılan 55 izolatın MGIT 960 sistemiyle 41’i (%74.5)
primer anti tüberküloz ilaçlara duyarlı, 14’ü dirençli (%25.5) bulundu. REBA
MTB-MDR, MGIT 960 ile karşılaştırılarak değerlendirildiğinde RIF direncini
saptamada duyarlılık %25 (CI 4.12-79.6), özgüllük %100, PPD %100, NPD % 93.7
olarak, INH direncini saptamada ise duyarlılık %22.2 (CI 3.47-59.9), özgüllük
%97.5, PPD %66.6, NPD %84.7 olarak belirlendi.

Sonuç: Literatürle birlikte
değerlendirildiğinde REBA MTB-MDR testinin, dirençli M. tuberculosis kompleksi klinik izolatlarında en yaygın görülen
mutasyonların hızlı tespitinde ve uygun tedaviye başlamada hız kazandırması
açısından değerli olduğu görülmüştür. Ancak bu testin sık görülmeyen
mutasyonları belirlemedeki kısıtlılığı ve ilaç direncinde başka mekanizmaların
varlığı nedeni ile rutin klinik laboratuvarlarda tek başına değil, geleneksel
duyarlılık testleri ile birlikte kullanılmasının daha doğru olacağı kanaatine
varılmıştır.