bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Limiting Fluid Intake on Clinical, Biochemical and Functional Parameters in Compensated Heart Failure Patients at a North Indian Hospital
Authors: Sharma Prafull , Guleria Vivek , Garg Salil , Batta Gaurav , Verma Niket , Malani Susheel K.
Published: November 2020

BACKGROUND Restriction of fluid is widely adopted as a strategic non-pharmacological therapy for patients with heart failure (HF). However, insufficient fluid leads to intravascular volume contraction further causing hypoperfusion of vital organs. Renal dysfunction and cardiac ischemia caused by hypoperfusion can further aggravate heart failure. Therefore, the authors decided to study the effect of fluid intake on various functional and cardiac parameters of patients of HF. METHODS 50 patients with a diagnosis of heart failure with reduced ejection fraction who had been discharged from the hospital since last 6 months and who were on restricted fluid therapy were included in the study. Patients were advised to visit the OPD once every 4 weeks and provide a record of their fluid intake. All patients irrespective of functional class were advised a fluid intake of 30 mL / day / Kg body weight. Functional status, biochemical parameters and clinical parameters were measured regularly until the end of 12 weeks. RESULTS There was marked improvement in the functional status of patients and statistically significant number was shifted from NYHA III and IV to NYHA I and II. PFI (Prescribed Fluid Intake) was associated with improvement of exercise tolerance in all NYHA Classes. Creatinine levels declined in all NYHA Classes with very high drop from 2.32 to 1.0 in NYHA Class IV. CONCLUSIONS Compensated HF patients should be prescribed physiologically correct dietary fluid intake based on body weight. This improves their functional capacity, biochemical parameters and left ventricular ejection fraction. KEYWORDS Heart Failure, Diet, Sodium-Restricted, Diuretics, Exercise Tolerance
Profile and Management of Blepharoptosis Patients in North India - A Two-Year Study
Authors: Anand Neebha , Deswal Jyoti , Khurana Ashok Kumar
Published: November 2020

BACKGROUND Blepharoptosis is a relatively common form of eyelid malposition in both children and adults. Along with being a cosmetic blemish, ptosis is associated with high incidence of amblyopia, especially in young children with severe ptosis. This can have a negative impact on psychosocial development of a child. Hence, it becomes necessary for a general physician as well as for a general ophthalmologist sitting at a primary health care centre, to know the clinical profile of such patients. We wanted to study the demography, clinical presentation and management of blepharoptosis patients seen in our institute over a period of 2 years. METHODS 45 patients with ptosis who reported at our tertiary care hospital in North India from January 2017 to December 2018, were included in the study. Demographic data, clinico-etiological profile, management of ptosis including outcome of surgeries performed was analysed retrospectively. Data was presented as frequencies and mean ± standard deviation (SD). RESULTS The study comprised of a total of 45 patients. The mean age of presentation was 17.4 years. Maximum number of patients i.e. 17 (37.7 %) were from the age group 11 - 20 years. Male to female ratio was 2.75 : 1. Congenital ptosis was found to be the most common type seen in 36 (80 %) patients. Simple congenital ptosis (34 patients) being the commonest among congenital type. 4 (17.7 %) patients had aponeurotic ptosis. 3 (6.6 %) patients had neurogenic ptosis. Myogenic ptosis was seen in 2 (4.4 %) patients. Majority of our cases had severe degree of ptosis (57.7 %) and poor LPS action (46.6 %). LPS resection was done in 21 (46.6 %) patients, LPS reinsertion in 1 (2.2 %), sling surgery in 18 (40 %) and Fasanella Servat operation in 1 (2.2 %) patient. 2 (4.4 %) patients were medically managed and 2 (4.4 %) were kept under observation. The outcome of surgery was good in 28 (62.2 %) patients, fair in 7 (15.5 %) and poor in 6 (13.3 %) patients. Presence of amblyopia was noted in 21 patients i.e. 46.7 % of the total patients. Marcus Gunn Jaw winking phenomenon was elicited in 2 (4.4 %) patients. Bell’s phenomenon was found in 4 (8.8 %) patients. 5 (11.1 %) patients had exotropia, 3 (6.6 %) had hypotropia and 1 (2.2 %) patient had complete ophthalmoplegia. CONCLUSIONS The study highlights the demographics, clinical profile and management of congenital blepharoptosis patients seen at a centre of excellence in North India. The study is helpful for ophthalmologists in guiding diagnosis, evaluation and management of such patients and hence, long-term successful outcome of this disease. KEYWORDS Blepharoptosis, Levator Resection, Frontalis Sling Surgery
Evaluation of Results of Resection-Reconstruction Using Autologous Non-Vascularized Fibular Graft in Giant Cell Tumour Affecting Distal Radius - A Prospective Study
Authors: Mallik Manoranjan , Ray Satyajeet , Maharaj Ramesh Chandra , Singh Gaurav Kumar , Nanda Debi Prasad
Published: November 2020

BACKGROUND Giant Cell Tumour (GCT) is a locally aggressive benign bone neoplasm characterized by proliferation of mononuclear stromal cells and many osteoclastlike multinucleated large giant cells affecting the epiphyseal segments of long bones mostly in females of 20 - 40 years age group. Distal radius is the third most common site of occurrence of GCT next to distal femur and proximal tibia. Resection or extended curettage remain the main modalities of treatment in Campanacci Grade I and II while en-bloc excision with reconstructive procedures, arthrodesis or amputation are the treatments of choice in Grade III with the latter two procedures leading to loss of joint function. Fibula being a non-weight transmitting bone of the lower limb, can be harvested in its proximal 1 / 3 rd and used for the reconstruction of the distal radius. In this study, we evaluate the functional and clinical results of resection and reconstruction using a nonvascularized fibula graft in the distal radius GCT. METHODS This is a prospective study of 20 patients diagnosed with GCT of distal radius either treated primarily at our institution or reviewed here after having been treated elsewhere. After confirmation of diagnosis, the patients underwent resection of the tumour and reconstruction of the distal radius using ipsilateral non vascularized fibula graft, fixed with dynamic compression plate. Follow-ups were done at regular intervals and radiological signs of graft healing, recurrence of tumour, wrist range of motion, and revised Musculoskeletal Tumour Rating Scale (MSTS) was used for assessing the functional outcome. RESULTS In our study, it was found that mostly females 13 (66.6 %) of the age group 30 - 35 yrs. were affected. The average grip strength achieved was 71 % (42 - 86 %) & average combined movements of 64 % (29 - 78 %) of contralateral normal side. Mean duration of union was 24 weeks (14 - 42 weeks). One case of non-union was seen which eventually achieved union with bone grafting. There was one case of soft tissue recurrence but the patient refused any further procedure. Complications were seen in 8 cases (41.6 %). We achieved excellent results in 15 (75 %), good in 2 (10 %), satisfactory in 2 (10 %) and poor in 1 (5 %) case. CONCLUSIONS We found that in GCT resection of the distal radius and reconstruction arthroplasty using autologous non-vascularized proximal fibular graft is useful in preserving the functional status as well as achieving satisfactory range of movement and grip strength with lesser chances of tumour recurrence. KEYWORDS Distal Radius, Giant Cell Tumour, Resection Reconstruction, Fibula
Role of HRCT in Interstitial Lung Disease with Radiographic Correlation
Authors: Shah Ankit Kumar , Kushwah Avadhesh Pratap Singh , Pandey Sonjjoy , Tomar Shashi Prabha
Published: November 2020

BACKGROUND Diffuse interstitial lung disease is on the rise in recent times. This could be attributed to number of causes / reasons. Environmental pollution is one of the important causes for the upswing. Increased exposure to inorganic dust, toxic fumes, certain drugs (gold, amiodarone, antibiotics etc.) and radiation can also cause ILD (Interstitial Lung Disease). METHODS This is a hospital based prospective observational study, conducted in the Department of Radiodiagnosis, NSCB Medical College and Hospital, Jabalpur. This study comprised of a total of 50 patients clinically diagnosed interstitial lung disease who had undergone x-ray chest and HRCT (High-Resolution Computed Tomography) Chest examination. RESULTS Incidence of interstitial lung disease was maximum in the middle age group of 51 – 60 years (38 %) with male predominance (58 %). Smoking habit was seen to be associated with 52 % of the cases suggesting association. 8 patients (16 %) had developed diffuse lung disease secondary to connective tissue disorder (rheumatoid arthritis, progressive systemic sclerosis and polymyositis). A confident diagnosis was made on the basis of chest radiograph alone in 11 patients (29 %). Among cases evaluated by HRCT Chest, 41 (82 %) cases showed specific patterns of ILD and nine cases (18 %) showed nonspecific patterns and were classified under unclassified IIP (Idiopathic Interstitial Pneumonia). Out of 41 cases, the most common ILD reported was IPF (20) followed by cases of idiopathic NSI, 8 cases of collagen vascular diseases, 2 cases suggestive of COP / BOOP, and smoking related ILDs were seen in 4 cases, and 2 cases of sarcoidosis were seen in the study. Occupational- and radiation-induced-ILD were seen in one case each. CONCLUSIONS Chest radiography is the initial imaging investigation in the evaluation of diffuse interstitial lung disease. HRCT is the imaging modality of choice to assess interstitial lung disease. It can detect lesion even when the chest radiograph is normal. HRCT can confirm the location, extent of disease, and pattern of disease. HRCT helps in the confident diagnosis of ILD as compared to chest radiography. Thus, it avoids lung biopsy in a large number of patients. HRCT is also useful in assessing the disease reversibility. Follow up of patients is better done by HRCT. KEYWORDS HRCT, Interstitial Lung Disease, Chest X-Ray, Ground Glass Opacity, Honeycombing
Benefit of Pranayama for Improvement of Pulmonary Function Tests (PFT) in Post Coronary Artery Bypass Grafting (CABG) Surgery Patients
Authors: Padhy Karunakara , Devi Nirupama , Kosuri Madhu , Ponangi Satyanarayana Venkat
Published: November 2020

BACKGROUND Incidence of Coronary Artery Disease (CAD) is increasing day by day. Cardiac rehabilitation is an important aspect of management of Coronary Artery Disease. Anuloma Viloma Pranayama is beneficial to cardiac patients as it increases parasympathetic activity and lowers blood pressure and respiratory rate. This study was designed to assess the benefit of Anuloma Viloma Pranayama as rehabilitation therapy in post Coronary Artery Bypass Grafting (CABG) surgery patients. Parameters of pulmonary function test (PFT) were measured before and after 3 months of performing CABG. METHODS The study was carried out in the Department of Cardiothoracic and Vascular Surgery, CARE Hospital, Visakhapatnam, Andhra Pradesh, in collaboration with Department of Psychology and Parapsychology and yoga village of Andhra University. CAD patients admitted to the hospital for CABG procedure were included in the study. Thirty patients were selected for performing pranayama (cases) and 30 patients were taken as controls. The study was approved by the institutional ethics committee of Care Hospital, Visakhapatnam, Andhra Pradesh. Patients who were admitted for CABG were advised to practice pranayama for 3 months along with normal rehabilitative steps from 3rd postoperative day. Pulmonary function test was measured by spirometry. Parameters like Forced Expiratory Volume in 1 second (FEV1), Forced Vital Capacity (FVC), FEV1 : FVC ratio, Peak Expiratory Flow Rate (PEFR) and Maximum Voluntary Ventilation (MVV) were measured. A comparison of pulmonary parameters was done between groups and statistically analysed using SPSS 20 software. P Valve < 0.05 was considered as significant. RESULTS Results of the study were analysed and compared between cases and controls. All the parameters of PFT improved significantly in pranayama group 3 months after CABG when compared with their preoperative values. There was also statistically significant improvement of all PFT parameters when compared between pranayama group (cases) and the control group. CONCLUSIONS Anuloma Viloma Pranayama is beneficial to postoperative CABG patients. It helps in reducing air way inflammation, air way collapse, and increases chest expansion, air way oxygenation along with improvement of pulmonary function tests. KEYWORDS Anuloma Viloma Pranayama, PFT, CABG
Evaluation of Different Scoring Systems in Predicting the Severity of Acute Pancreatitis
Authors: Harsoda Rohan J. , Jaishree Sharma Vipin , G.V Krishna Prasad
Published: November 2020

BACKGROUND Accurate prediction of the severity of acute pancreatitis will help in identifying patients at increased risk for morbidity and mortality. We wanted to evaluate the different scoring systems in predicting the severity of acute pancreatitis. METHODS This cross-sectional study was undertaken in the Department of Surgery at a zonal hospital between April 2013 and December 2014. RESULTS 40 patients were selected and enrolled in the study as per the selection criteria. 20 (50 %) patients had fair outcome and 20 (50 %) had a poor outcome. Accuracy of different scoring systems in predicting patient outcome ranged from 45 % (48-hr APACHE II) to 62.5 % (Goris MOF at baseline and 48 hr). Baseline Goris MOF was 70 % sensitive and 55 % specific in prediction of poor outcome. It had an accuracy of 62.5 % in prediction of outcome. 48-hr Goris MOF was 80 % sensitive and 45 % specific in predicting the outcome. Baseline APACHE II scores were below the cut-off level in all the patients. 48-hr APACHE II scores were 5 % sensitive and 100% specific for prediction of outcome. Ranson score > 3 was 25 % sensitive and 90 % specific in the prediction of outcome. Balthazar score > 6 was 65 % sensitive and 55 % specific in prediction of outcome. Ranson score was found to have a limited sensitivity for different outcomes (ranging from 21.1 % to 50 %) but was found to have a high specificity (83.8 % to 90 %). CONCLUSIONS Goris scoring system (at 48 hrs) was found to be highly sensitive to different poor outcomes as well as duration of hospital stay. It also correlated with Balthazar scoring system, which was also highly sensitive to different poor outcomes studied. KEYWORDS Acute Pancreatitis, Prediction, Scoring System, APACHE II, Goris MOF, Ranson’s Score, Balthazar Score
Clinical Profile of Cerebral Venous Thrombosis in Correlation with Anticardiolipin Antibody Titre
Authors: Devegowda Lachikarathman , Nanjappa Veena , B Prabhakar , Banu Asima , Trivedi Anindya Sundar , Nagraj Suneetha
Published: November 2020

BACKGROUND Anticardiolipin antibodies (aCL) have been recognized as an independent risk factor for an increased risk of thrombosis. The aim of our study was to assess the prevalence of aCL antibodies in patients with CVT (Cerebral Venous Thrombosis) and correlate clinical profile of CVT with anticardiolipin antibody titre. METHODS Forty-two patients with CVT diagnosed by neuroimaging were investigated for the presence of aCL. We compared the clinical profile of ACL antibody positive and negative group. RESULTS Anticardiolipin antibodies were detected in 30.9 % of CVT patients. In anticardiolipin antibody negative group, mean age was 26.76 ± 8.49 years, compared to positive group in which mean age was 32.00 ± 10.88 years which was statistically not significant. In our study, mean leukocyte count was low among aCL positive group compared to negative group (8396 ± 2694.8 vs. 10472.41 ± 3353.5), which was statistically not significant. Both positive and negative groups were comparable with respect to other clinical findings. CONCLUSIONS Anticardiolipin antibodies (aCL) have been recognized as an independent risk factor for an increased risk of thrombosis. Its presence in patients with CVT requires lifelong anticoagulation to prevent recurrence. So all patients of CVT need to be evaluated for the presence of anticardiolipin antibodies. KEYWORDS Cerebral Venous Thrombosis, CVT, Anticardiolipin Antibodies
AGRONOMIC PERFORMANCE OF CORN IN FUNCTION OF METHODS OF APPLICATION AND DOSES INOCULATED WITH Azospirillum brasilense
Authors: FIORINI IVAN VILELA ANDRADE , TONIAL MAURÍCIO ESCOBAR , PEREIRA CASSIANO SPAZIANI , SABINO DANIELE CRISTINA COSTA , DIAS IARA GARCÊS , TACCA JULIO GUILHERME , SCHOFFEN MATEUS EMANUEL
Published: November 2020

Nitrogen supplementation becomes necessary when trying to increase yields of off-season corn crop grown in rotation with early-maturing soybean crop. Biological nitrogen fixation helps reduce the use of nitrogen fertilizers through the inoculation of nitrogen-fixing associative bacteria, such as those of the genus Azospirillum. This study aimed to evaluate the agronomic performance of corn hybrid DKB390Y in response to different application methods as the inoculant and doses of inoculant with Azospirillum brasiliense. The experiment was conducted in a property adjacent to Federal University of Mato Grosso (Sinop campus), between February and July 2018. The experimental design included randomized blocks in a 3×5 factorial arrangement, replicated four times, thereby totaling 60 plots (with three application methods: foliar spraying, spraying foliar with bovine gelatin, and with a paint roller [Black Decker Rapid Roller BDPR400-wool] and five doses of inoculant: 0, 100, 200, 400 and 800 mL ha-1). No differences in chlorophyll content at the bottom of the plant, plant height, and leaf area index were observed when varying the application methods. However, leaf nitrogen level, dry mass and grain yield changed when the application method used for inoculation changed. When evaluating doses, the control was found to be superior to the other treatments based on chlorophyll content at the bottom of the plant, plant height,leaf area, leaf nitrogen, and dry mass values. Grain yield was found to be superior with foliar inoculation at 100 mL ha-1 method foliar spray and 200 mL ha-1 methods foliar application with bovine gelatin.
INFLUENCE OF TRANSGENIC MAIZE ON BEHAVIOR OF ADULT FEMALE OF Spodoptera frugiperda (J. E. SMITH) (LEPIDOPTERA: NOCTUIDAE)
Authors: NASCIMENTO PRISCILLA TAVARES , MATIELLO FADINI MARCOS ANTONIO , VON PINHO RENZO GARCIA , SOUZA CAMILA DA SILVA FERNANDES , VALICENTE FERNANDO HERCOS
Published: November 2020

It is known that genetic manipulation of plants can cause pleiotropic effects or mutations originated from the incorporation of an exogenous gene, which may interfere with foraging of herbivores. Little is known about how herbicide-tolerant plants (singular event), insect-resistant plants (singular event), and herbicide-tolerant plus insect-resistant plants (stacked event) affect foraging of Spodoptera frugiperda. The objective of this study was to evaluate if singular and stacked maize events interfere with the quantity and quality of S. frugiperda eggs. The hybrids DKB390 (VTPRO, VTPRO2, VTPRO3), DKB390 (isogenic) and Ag 3700 RR2 were evaluated. Choice and non-choice tests for oviposition preference of S. frugiperda, in plants with and without injuries, were performed in a greenhouse. The size of egg masses and the number of hatched larvae were evaluated. Larger egg masses and higher number of hatched larvae per plant were found in transgenic plants. The conclusion was that S. frugiperda females modify their oviposition behavior in the presence of transgenic and non-transgenic maize hybrids, especially when they are injured. However, the females do not discriminate between singular or stacked hybrid for oviposition.
SUFFICIENT NUMBER OF REPLICATES FOR ESTIMATION OF DISSIMILARITY MEASURES AMONG MAIZE CULTIVARS
Authors: ​CARGNELUTTI FILHO ALBERTO , TOEBE MARCOS
Published: November 2020

The objective of this work was to determine the sufficient number of replicates for estimation of dissimilarity measures among maize cultivars. Data of five variables were used, which were evaluated in an experiment with 15 maize cultivars, in randomized block design with nine replicates. A number of 511 data files were formed, being 9, 36, 84, 126, 126, 84, 36, 9, and 1 obtained, respectively from 1, 2, 3, 4, 5, 6, 7, 8, and 9 replicates. Three dissimilarity matrices were determined between i and i’ cultivars containing, respectively, Euclidean, Manhattan, and Chebyshev distances. For each of the 105 distances between cultivars, in each dissimilarity measure, the power function was adjusted for the coefficient of variation of the (dependent variable) as a function of the number of replicates (independent variable), totaling 315 equations. For each equation, the abscissa axis value (Xs, sufficient number of replicates) was determined, corresponding to the maximum curvature point. With the increase of the number of replicates, there is an improvement in the accuracy of the estimates of dissimilarity measures among maize cultivars, however, the gains in precision decrease gradually. Six replicates are sufficient to estimate the dissimilarity measures among maize cultivars expressed by the Euclidean, Manhattan, and Chebyshev distances.
OS DESAFIOS DOS PROCESSOS FORMATIVOS DOS PROFESSORES INCLUSIVOS: PRÁTICAS PEDAGÓGICAS DOS DOCENTES NA EDUCAÇÃO BÁSICA
Authors: Ziesmann Cleusa Inês , Thomas Isabel Follman
Published: November 2020

Sabemos que um dos grandes desafios das instituições de ensino é proporcionar o acesso e a permanência dos alunos, em todos os níveis de ensino, respeitando as suas especificidades e necessidades durante o seu processo de aprendizagem. Assim, o objetivo é perceber como os professores compreendem a inclusão a partir de suas práticas pedagógicas e suas concepções sobre como essas práticas podem afetar os sujeitos no processo de aprendizagem e desenvolvimento na sala de aula. A pesquisa contou com uma revisão bibliográfica completada pela pesquisa de campo qualitativa. Para a produção de dados utilizou-se a observação das atividades em sala de aula e entrevistas semiestruturadas com professoras do ensino fundamental, educadoras especiais e monitoras que atendem alunos incluídos em duas escolas municipais.  Para a Análise de Conteúdo foi escolhida as concepções de Bardin (2011). Acreditamos que nossas inferências nos espaços investigados podem contribuir para fomentar as discussões e reflexões sobre o processo inclusivo, contribuindo para que as práticas pedagógicas venham ao encontro das necessidades dos educandos e aos direitos para uma educação de qualidade em todos os níveis de ensino.
Attitudes of local people towards community based eco-tourism in the Sundarbans
Authors: Dey T. , Kamruzzaman M. , Islam M. A. , Bachar B. K. , Pitol M. N. S.
Published: November 2020

Tourism especially nature based tourism is increasing throughout the world day by day. The Sundarbans Reserve Forest (SRF) in Bangladesh is a suitable place for developing tourism. The purpose of the study was to find out the attitudes of local people’s towards community based eco-tourism (CBET) in the Sundarbans. The study was carried out by a questionnaire survey with purposive selection based on diversity of occupation and sex in that area. A 5- point rating Likert scale was used to measures the local people’s attitude towards community based eco-tourism. Most of the people of the study are poorly based on income and depends on the forest as well as are fisherman among male and housewife among women. Natural beauty of this area, scope to watch wildlife, tourist security, house or eco-cottage quality, toilet and bathing facilities are favorable as well as communication and infrastructure facilities are an obstacle for developing CBET here. CBET will increase alternative job opportunities and income as well as it will reduce disturbance of forest and illegal harvesting according to the respondents. Forest Department is cooperative and tourists are more conscious now than before. People are now satisfied with CBET and keen to involve with this. This research is important for tourism policymakers in Bangladesh for their decisions.
Yield performance of Boro rice through integrated application of vermicompost, biochar and urea
Authors: Alvi A. A. , Tumpa F. A. , Hossen K. , Hossain B.
Published: November 2020

The present investigation was executed at Agricultural Research Field, Noakahali Science and Technology University, Noakhali, Bangladesh to access the effects of variety and integrated application of vermicompost, biochar and urea on efficiency of boro rice yield. The experiment was accomplished during the period from November 2018 to May 2019. It was completed in a randomized complete block design (RCBD) with three replications. The treatments assigned in a factorial arrangement of 2 × 4, with 2 varieties of rice (V1-BINA dhan 8, V2- BINA dhan 10) and 4 integration of vermicompost, biochar, and urea (T1: Vermicompost-2.5 t ha-1, T2: Vermicompost-2 t ha-1+ Biochar 0.5 t ha-1, T3: Vermicompost-1.5 t ha-1+ Biochar 1 t ha-1 and T4: Vermicompost-1.5 t ha-1 + Urea-150kg ha-1/0.15 t ha-1). Data were collected to analyze growth and yield contributing characters of boro rice. All the parameters were not statistically significant to differ. According to variety highest grain (3.73 t ha-1) and straw (2.8 t ha-1) yield was found from BINA dhan 10 in comparison with BINA dhan 8. In case of integrated application of vermicompost, biochar and urea, superior grain and straw yield were obtained from T4: Vermicompost-1.5 t ha-1 + Urea-0.15 t ha-1 whereas lowest grain yield (3.01 t ha-1 recorded from integrated application vermicompost and biochar. In combine maximum grain (4.92 t ha-1) and straw (4.40 t ha-1) yield was noted from BINA dhan 10 alone with integrated application of vermicompost and urea whereas the lowest data (grain: 2.50 t ha-1; straw: 1.64 t ha-1) was found from BINA dhan 8 along with vermicompost and biochar.
BISHOP NIKODIM BUSOVIĆ AND UNIATISM IN LATE 17TH AND EARLY 18TH CENTURY DALMATIA AND BOKA
Authors: MATIĆ MARINA
Published: November 2020

This article deals with the role and activities of Bishop of Dalmatia Nikodim Busović at the end of the seventeenth century and the beginning of the eighteenth century. For Dalmatia and Boka, these were tumultuous times caused by the Morean War (1683–1699), with increased population migrations and increased Uniate pressures on the local Serbian population. During this turmoil, the Uniate archbishop of Philadelphia, Meletius Tipaldi, attempted to expand his influence and bring the Serbian Orthodox population in Dalmatia under his jurisdiction. At the same time, Catholic bishops in Dalmatia and Boka, protégés of the Congregation for the Propagation of the Faith, were pressuring Serbs to embrace Uniatism. Under these circumstances, Bishop Nikodim Busović managed for more than a decade to skillfully maintain the Serbian ecclesiastical organization under Venetian rule. After his suspension, Serbs in the coastal area of Dalmatia and Boka did not have a bishop until late eighteenth century.
ANCIENT GREEKS AND SUICIDE IN THE TRAGEDIES: SOPHOCLES᾿ AJAX AND EURIPIDES᾿ HERACLES
Authors: MARIČIĆ GORDAN , ŠAJIN ŽELJKA
Published: November 2020

This paper analyzes attitudes towards suicide in ancient Greece as presented in Greek tragedies. Although suicide as a social phenomenon was a common motif in various ancient plays, the focus here will be on two tragedies, Sophocles᾿ Ajax and Euripides᾿ Heracles, in which suicidal tendencies motivated by a loss of honor are most clearly depicted. In these plays, the two heroes are faced with a dilemma: choosing between an honorable death or a life spent in shame. In accordance with the ideals of his creator and the strict heroic code, Sophocles’ Ajax decides to commit suicide. Euripides’ Heracles, however, broken and devastated, chooses life by relying only on himself and his friendship with Theseus.
FIRST RECORD IN EUROPE OF CINARA SHINJII INOUYE (APHIDIDAE LACHNINAE) ON THE JAPANESE WHITE PINE, PINUS PARVIFLORA SIEBOLD & ZUCC.
Authors: SCHEURER STEPHAN , BINAZZI ANDREA , ROVERSI PIO FEDERICO , BINAZZI FRANCESCO
Published: November 2020

The Japanese Cinara shinjii Inouye, was occasionally collected in a private garden in Raddusch-Spreewald (Brandenburg), Germany, on an ornamental Japanese white pine, Pinus parviflora Siebold & Zucc. The species is redescribed providing morphological data of apterae, alatae virginoparae and oviparae females, in order to facilitate morphological identification. This finding, that represents the first record of C. shinjii in Europe, is evaluated in the context of the emerging issue represented by biological invasions. A brief overview of Cinara species alien to Europe is presented with a short critical analysis of their distribution as well as of their ecological and economic impact
Apresentação
Authors: Costa Greciely Cristina da
Published: November 2020

Compondo o volume 23, a Línguas e Instrumentos Linguísticos, apresenta seu número 46 constituído de nove artigos na Seção Aberta, um ensaio na Seção Crônicas e Controvérsias e uma Resenha. Na Seção Aberta, o primerio estudo “O cotidiano na História das Ideias Linguísticas”, de Ana Cláudia Fernandes Ferreira, trata de uma teorização discursiva sobre o cotidiano, com base em Michel de Certeau, Michel Pêcheux, Sylvain Auroux e Eni Orlandi. A autora propõe pensar que o saber linguístico cotidiano não se recobre pela noção de saber epilinguístico, salientando que os saberes linguísticos cotidianos, enquanto efeitos ideológicos, podem ser epilinguísticos ou metalinguísticos.
Efektifitas Propolis Pada Perbaikan Histopatologi Hepar Mencit Betina yang Dipapar Logam Berat Pb Asetat
Authors: Rachmani Sartika Dewi
Published: November 2020

ABSTRAKTujuan penelitian ini adalah untuk mengetahui pengaruh propolis terhadap gambaran histopatologi hati pada mencit (Mus musculus) betina yang terpapar timbal asetat. Subjek penelitian adalah 25 ekor mencit galur BALB / C dengan berat rata-rata 25-35 gram berumur 8 minggu, dibagi menjadi 5 kelompok perlakuan dan terdiri dari 5 ekor per kelompok. Kelompok K diberi larutan Tween 80 dengan dosis 0,5 mg / kg BB selama 20 hari berturut-turut. Kelompok K + yang hanya diberi timbal asetat dengan dosis 10 mg / kg BB secara oral selama 10 hari. P1, P2, P3 diberikan larutan timbal asetat 10 mg / kg BB secara oral selama 10 hari. 10 hari berikutnya diberikan propolis dengan dosis P1 200 mf / kg BB, P2 400 mg / kg BB, P3 800 mg / kg BB. Pada hari ke 21 mencit dibedah untuk mengamati tingkat kerusakan yang terjadi. Semua data dilakukan menggunakan uji statistik dengan uji Kruskal Wallis dan jika terdapat perbedaan yang nyata antar kelompok perlakuan (p <0,05) maka dilanjutkan uji Mann-Whitney. Hasil penelitian diperoleh bahwa propolis lebah dapat memperbaiki kerusakan sel hati mencit betina yang terpapar timbal asetat. Peningkatan dosis propolis tidak efektif dalam memperbaiki kerusakan sel hati mencit betina yang terpapar timbal asetat.
BRAND EQUITY POLÍTICO: UMA ANÁLISE SOBRE A CONSTRUÇÃO DA MARCA POLÍTICA
Authors:   IFSP Instituto Federal de São Paulo, Assed Neto Malek , e Silva Chaves Eduardo de Paula ,   IFSP Instituto Federal de São Paulo
Published: November 2020

O marketing tem função essencial para o sucesso dos produtos, pois se apresenta como um elo entre os bens e serviços com seus consumidores e por isso tem importante influência nas definições de estratégias e posicionamento das empresas. Diante disso o gerenciamento das marcas tem sido alvo de estudos e investimentos, pois representam um ativo intangível da empresa e, portanto não pode ser copiado pela concorrência. Aumentar o valor dessa marca é vital para se diferenciar dos concorrentes e agregar vantagem competitiva, este efeito é o que se conhece como brand equity. Este trabalho apresenta uma abordagem do conceito de brand equity aplicado ao contexto político nacional, onde serão feitas análises sobre um modelo que constituí o political brand equity e posteriormente a visão dos eleitores sobre os partidos políticos brasileiros, as dimensões de um modelo de political brand equity e suas relações com constructo final, e descrever quais dessas dimensões têm relevância em um processo de decisão de voto.
ANÁLISE DO TEMPO EMPRESARIAL PELA IDENTIDADE ORGANIZACIONAL
Authors:   Instituto Federal de São Paulo, Kuchiniscki Zozimo de Almeida Mariana , e Silva Chaves Chaves Eduardo de Paula ,   Instituto Federal de São Paulo
Published: November 2020

Cada organização é um sistema único e flexível. As adaptações são estruturadas seguindo parâmetros existentes no cenário mercadológico, desencadeando estratégias específicas através dos valores promovidos pela cultura organizacional. Sabendo-se que a Identidade Organizacional promove comportamentos coletivos semelhantes, esta pesquisa visa estudar a correlação do tempo empresarial e seu respectivo aumento pela Identidade Organizacional, verificando a interação do meio através das semelhanças e possíveis divergências das ações estipuladas. Desta forma, esta pesquisa é quantitativa e contém dados primários coletados via surveys, com respostas de indivíduos geracionais diferenciados e empresas diversas. Assim, o resultado ressalta que as influências se diversificam com o passar das gerações, reforçando os conceitos da carreira proteana e carreira sem fronteiras.
Influências Ocasionadas Pelo Clima Organizacional De Uma Empresa No Momento Da Crise De Pandemia
Authors:   Faculdade de São Marcos, de Oliveira Lenoir José , Hahn Biegelmeyer Uiliam ,   Faculdade de São Marcos, Castilhos Nádia Cristina ,   Faculdade de São Marcos, Camargo Maria Emília ,   Universidade de Caxias do Sul, Zanella Tainá ,   Faculdade de São Marcos, Nunes Pozzo Danielle ,   Universidad de La Costa Colombia
Published: November 2020

As organizações buscam a sobrevivência e crescimento no mercado no qual estão inseridas. Em meio a esta busca, as empresas perceberam que as pessoas possuem papel importante na ampliação de seus negócios, de modo que, é por meio delas que as metas são alcançadas. A evolução no modo de gerenciar as pessoas é demonstrada através da preocupação em promover um ambiente organizacional onde as pessoas estão satisfeitas e motivadas, isso implica verificar como elas percebem o clima organizacional. Nesta busca, o presente estudo visa por meio de instrumento de pesquisa a avaliação do clima organizacional sob a ótica dos colaboradores de um determinado setor em uma empresa metalúrgica na cidade de São Marcos/RS. Para isso, foi disponibilizado a cada funcionário um instrumento com afirmativas referente a variáveis que interferem no clima organizacional. Na sequência, foi realizada a tabulação dos resultados e a análise por meio de método quali-quantitativo, que através de análise de frequência, permitiu verificar resultados superiores para as afirmativas relacionadas às variáveis, sendo observado a possibilidade de melhorias para itens como recursos e treinamentos aos colaboradores, a questão salarial, do transporte e investimento em educação. Através dos resultados encontrados foi sugerido à empresa ações como, por exemplo, a estruturação do plano de cargos e salários, a revisão do sistema de transporte, entre outros que, ao serem implantadas, irão contribuir favoravelmente para um clima organizacional satisfatório.
Multi-Method Determination of Antioxidant Capacity, Phytochemical and Biological Investigation of Four Different Solvent Extractives of Leucophyllum frutescens (cenizo)
Authors: Ahmad Imtiaz , Ahmad Saeed , Rao Huma , Shaukat Umer , Shahzad Muhammad Nadeem , Rehman M. Sajid-ur- , Basit Abdul , Arshad M. Adeel , Ahmad Bilal
Published: November 2020

The four solvent extractives obtained from aerial parts of Leucophyllum frutescens were evaluated for their Total Antioxidant Activity (TAA) by ammonium molybdate method, scavenging potential by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and Trolox-Equivalent Antioxidant Capacity (TEAC) assays, metal-reducing potential by Cupric Reducing Antioxidant Capacity (CUPRAC) and Ferric Reducing Antioxidant Power (FRAP) assays, Total Phenolic Content (TPC), Total Flavonoid Content (TFC) and their biological activities. The study concluded that BULE exhibited total antioxidant activity (226.235±1.222 mg AA.Eq.gm-1 DE±S.D) by molybdate method, CHLE exhibited more scavenging potential (DPPH 209.589±8.500 mg trolox Eq.gm-1 DE±S.D and TEAC 210.166±7.954 mg trolox Eq.gm-1 DE±S.D) and reducing potential (CUPRAC 646.889±16.889 mg trolox Eq.gm-1 DE±S.D & FRAP 472.981±15.625 mg trolox Eq.gm-1 DE±S.D). Phytochemical quantification concluded high TPC by BULE (189.369±1.393 mg GA.Eq.gm-1 DE±S.D) and high TFC by CHLE (232.458±1.589 mg Qu.Eq.gm-1 DE±S.D). Strong inhibition of α-glucosidase and urease enzymes was observed by HELE (IC50 0.3321±0.007 mg.ml-1±SD) and BULE (IC50 4.09±0.357 mg.ml-1±SD) extractives, respectively. The hemolytic effect shown by hexane extract (HELE) was higher with HA50 25.545±0.927 ug.ml-1±SD whereas methanol (MELE), chloroform (CHLE), and butanol (BULE) exhibited hemolytic effects at higher concentration with HA50 400.067±1.364, 321.394±1.332, and 332.957±0.465 µg.ml-1±SD, respectively. GC-MS profiling of HELE of L. frutescens was performed for qualitative analysis. The principal phytochemicals tentatively identified by GC-MS analysis of HELE accounts for fatty acids (60.221%), lignans (17.687%), ketones (3.358%), phenols (2.584%), sesquiterpenes (1.265%), and aldehydes (0.345%).
Different Modulatory Effects of Four Methicillin‐Resistant Staphylococcus aureus Clones on MG-63 Osteoblast-Like Cells
Authors: Musso Nicolò , Caruso Giuseppe , Bongiorno Dafne , Grasso Margherita , Bivona Dalida A. , Campanile Floriana , Caraci Filippo , Stefani Stefania
Published: November 2020

Staphylococcus aureus is a Gram-positive bacterium causing a range of mild to life-threatening infections including bone infections such as osteomyelitis. S. aureus is able to invade and persist within non-professional phagocytic cells such as osteoblasts. In the present study four different S. aureus strains, 2SA-ST239-III, 5SA-ST5-II, 10SA-ST228-I, and 14SA-ST22-IVh were tested for their ability to modulate cell viability in MG-63 osteoblast-like cells following a successful invasion and persistence. Methicillin-sensitive S. aureus (MSSA) ATCC-12598-ST30 was used as control. Despite the demonstrated similar abilities of internalization and persistence of ATCC-12598-ST30, 2SA-ST239-III, and 14SA-ST22-IVh strains in MG-63 osteoblast-like cells under our experimental conditions, we demonstrated that the decrease in cell viability was due to the different behavior of the considered strains, with the number of intracellular bacteria playing a limited role. We focused our attention on different cellular biochemical functions related to inflammation, cell metabolism, and oxidative stress during osteoblast infections. We were able to show that: 1) ATCC-12598-ST30 and 2SA-ST239-III were the only two clones able to persist and maintain their number into the cellular hostile environment during the entire period of infection; 2) 2SA-ST239-III was the only clone able to significantly increase the gene expression (3 and 24 h) and protein secretion (24 h) of both interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) in MG-63 osteoblast-like cells; 3) the same clone determined a significant up-regulation of transforming growth factor-β1 (TGF-β1) and the metabolic marker glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNAs at 24 h post infection; 3) neither the MSSA nor the four MRSA strains induced oxidative stress phenomena in MG-63 cells, although a very different expression pattern towards nuclear factor E2-related factor 2 (Nrf2) and its downstream gene heme oxygenase 1 (HO-1) activation was observed among the different clones. Our results can open a new way of considering therapies, going in the direction of an individualized therapeutic strategy that should take into account the difference existing between MSSA and MRSA as well as the distinctive features of the different clones. Not only, therefore, a different antibiotic approach but also a starting point for considering different host factors, i.e. the modulation of specific cytokines such as IL-6, TNF-α, and TGF-β1.
Seroprevalence of Bovine Brucellosis in Selected Districts of Zambia
Authors: Mfune Ruth Lindizyani , Mubanga Melai , Silwamba Isaac , Sagamiko Frederick , Godfroid Jacques , Hangombe Bernard M. , Muma John B.
Published: November 2020

Brucellosis is an infectious zoonosis that has huge economic and public health implications globally. The disease is prevalent in humans, livestock and wildlife in Sub Saharan Africa. A cross-sectional study was conducted between 6th May 2017 and 31st July 2020 during which 1712 sera from 177 cattle herds in Southern, Western and Eastern provinces of Zambia was collected and screened against brucellosis. Rose Bengal Test and c-ELISA were used in serial testing for detection of antibodies against Brucella species. Results: A total of 127 animals and 37 herds tested positive, giving an overall individual and herd seroprevalence of 7.42% (CI: 0.61-0.86) and 20.9% respectively. Namwala district recorded the highest seroprevalence (12.2%) while Lundazi had the lowest (0%). A higher seropositivity was observed among female animals (8.5%), those aged between 11 and 17 years (14.1%) and pregnant cows (13.8%). Conclusions: Brucella seroprevalence among traditional cattle in Zambia remains high. It is vital that control programmes against bovine brucellosis are introduced in order to reduce its zoonotic impact on human health and increase animal production.
Anxiety Related Attention Bias in Four to Eight-Year-Olds: An Eye-Tracking Study
Authors: Stuijfzand Suzannah , Reynolds Shirley , Stuijfzand Bobby , Dodd Helen
Published: November 2020

(1) Background: There is robust evidence of an attention bias-anxiety relationship in children, but lack of appropriate methods has limited the number of studies with children younger than 8 years old. This study used eye-tracking as a measure of overt attention in young children. The aim of this study was to assess anxiety related attention bias in children aged 4 to 8 years. Age was considered as a moderator and the influence of effortful control was investigated. (2) Method: A community sample of 104 children were shown pairs of happy-neutral and angry-neutral faces. Growth curve analyses were used to examine patterns of gaze over time. (3) Results: Analyses revealed moderation by age and anxiety, with distinct patterns of anxiety-related biases seen in different age groups in the angry-neutral face trials. Effortful control did not account for age related effects. (4) Conclusions: Results support a moderation model of the development of anxiety in children.
Влияние возраста на распространение новой коронавирусной инфекции в семьях, школах и во всём населении
Authors: Гольдштейн Эдвард
Published: November 2020

Актуальность: Новая коронавирусная инфекция распространяется неравномерно в разных возрастных группах. Изучение распространения новой коронавирусной инфекции усложняется тем, что количество случаев заражения новой коронавирусной инфекцией в населении значительно превышает количество лабораторно подтверждённых случаев новой коронавирусной инфекции. Мы провели обзор литературы для того, чтобы оценить связь между возрастом и восприимчивостью к новой коронавирусной инфекции, и изучить влияние возраста и других факторов на распространение новой коронавирусной инфекции в семьях, среди школьников в разных возрастных группах, среди людей старше 60-и лет, и среди людей в возрасте 18-59 лет. Результаты: По сравнению с людьми в возрасте 18-59 лет, восприимчивость к новой коронавирусной инфекции несколько выше у людей старше 60-и лет, и ниже у детей, причем у детей восприимчивость к инфекции в целом увеличивается с возрастом. Большинство серологических исследований указывают на то, что среди разных возрастных групп, уровень заражения новой коронавирусной инфекцией самый высокий у людей в возрасте 18-59 лет, особенно в возрасте 18-39 лет. При отсутствии мер по контролю за распространением инфекции в школах, новая коронавирусная инфекция активно распространяется среди старшеклассников, и относительно менее активно распространяется среди учеников младших классов. При наличии мер по контролю за распространением инфекции в школах, таких как ношение масок, уменьшение количества учеников в классе и активное тестирование школьников/учителей на новую коронавирусную инфекцию с последующим карантином для контактных лиц, распространение новой коронавирусной инфекции в школах ограничено. Выводы: Учитывая повышенную восприимчивость к новой коронавируной инфекции и повышенный риск осложнений при инфицировании у людей старше 60-и лет, меры по уменьшению количества контактов для людей старше 60-и лет (такие как выделение отдельных часов работы магазинов для людей старше 60-и лет) необходимы для уменьшения уровней госпитализации и смертности от новой коронавирусной инфекции. Меры по контролю за распространением инфекции в школах, таких как ношение масок и активное тестирование на новую коронавирусную инфекцию, особенно среди старшеклассников/учителей, способствуют уменьшению распространения инфекции в школах. Меры, направленные на уменьшение количества контактов среди людей в возрасте 18-59и лет способствуют уменьшению распространения инфекции во всём населении.
Comparison of Umbilical Cord Blood Transplantation with Bone Marrow or Peripheral Blood Derived Stem-Cell Transplantation in Transfusion Dependent Thalassemia Patients: A Single Center Propensity Score Matching Analysis
Authors: Rostami Tahereh , Kasaeian Amir , Kiumarsi Azadeh , Rad Soroush , Mohammadzadeh Elham , Mousavi Seied Asadollah
Published: November 2020

Background: Successful hematopoietic stem cell transplantation (HSCT) could cure the hematological manifestations of transfusion-dependent thalassemia (TDT), but introduces risks of morbidity and mortality. Umbilical cord blood transplantation (UCBT) is considered as an acceptable strategy, by providing a condensed graft versus host disease (GvHD). This paper compares the outcomes of UCBT with HSCT from peripheral blood and bone marrow in TDT patients.Methods: Between 1998 and 2014, 10 patients with TDT underwent UCBT, which were matched with 20 patients undergone BMSCT and 20 patients undergone PBSCT, by using propensity score matching (PSM) for age, gender and thalassemia class. All patients received the same myeloablative conditioning regimen and were transplanted from a fully HLA matched sibling donor. Results: The median follow-up time after HSCT was 5.7 years. Rejection incidence was 70.0% (95% CI = 28.1%-90.4%) after UCBT, 25.6% (95% CI = 8.9%-46.4%) after BMSCT, and no rejection occurred in the PBSCT group. Acute GVHD incidence was 20.0% (95% CI = 2.6%-49.0%), 35.0% (95% CI = 15.1%-55.8%), and 40.0% (95% CI = 18.6%-60.6%) in patients undergone UCBT, BMSCT and PBSCT, respectively (P=0.62). The incidence of chronic GVHD was 7.2% (95% CI = 0.3%-28.7%), and 35.2% (95% CI = 13.7%-57.8%) in patients undergone BMSCT and PBSCT, respectively (P=0.026) and none of the patients in the UCBT group experienced chronic GvHD. Conclusions: Although the overall survival is not significantly influenced by the graft source, due to the high incidence of rejection after UCBT, the probability of thalassemia free survival is very low in these patients.