bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Tingkat Kepuasan Pengguna Sistem Informasi Kerja Praktek dan Skripsi (SKKP) Menggunakan Metode End User Computing Satisfaction (EUCS)
Authors: Setyoningrum Nanny Raras
Published: September 2020

The advantages of information technology in the education has developed a lot, especially in universities. An example of the application of tertiary level information technology is the delivery of information presented through the university's official website. One of the web-based systems owned by the STTI Tanjungpinang is the Sistem Informasi Kerja Praktek dan Skripsi (SKKP). With this technology, the process of submitting titles to the registration of practical work trials and student theses has been switched online. Analysis of the level of satisfaction is important to know the extent of expectations and perceptions of system users in an effort to achieve the perfection of an information system and can meet user expectations. One method in analyzing user satisfaction levels is end user computing satisfaction (EUCS). Dimensions in EUCS consist of content, accuracy, format, ease of use and timeliness. This type of research is descriptive research that is intended to describe the phenomena that exist, which took place at this time or in the past. Data collection methods included observation, interviews and distribution of questionnaires with a sample of 35 respondents who were active SKKP users. The results of the analysis of user satisfaction level SKKP STTI Tanjungpinang using the EUCS method of 78.69% with a gap of 21.31% means users are in the range of satisfied categories. From the five dimensions, the variable content has the smallest gap of 8.69% while the largest gap is in the accuracy variable, which is 32.02%.
Penerapan UCD (User Centered Design) Pada Perancangan Sistem Informasi Manajemen Aset TI Berbasis Web di Bid TIK Kepolisian Daerah Kepulauan Riau
Authors: Supardianto Supardianto , Tampubolon Arief Binsar
Published: September 2020

Sulitnya melakukan penelurusan dan pengontrolan aset TI mengakibatkan kurang baiknya manajemen aset TI yang ada di Bid TIK sehingga kesulitan ketika diminta laporan-laporan mengenai aset TI yang dimiliki. Dalam penelitian ini, masalah-masalah ini dapat diselesaikan dengan membangun sistem informasi yang mampu mengelola aset TI di Bid TIK. Penelitian ini bertujuan untuk merancang dan membuat sistem informasi manajemen aset TI berbasis web dengan menerapkan UCD (user centered design) dengan pengujian usability serta pengembangan sistem infomasi dengan kuisioner dan usability testing. Pengujian black box dilakukan untuk memvalidasi fungsionalitas yang ditetapkan pada kebutuhan user saat wawancara. Hasil akhir dalam membangun sistem informasi ini adalah Berdasarkan Usability Testing dengan System Usability Scale, Sistem informasi manajemen aset TI ada pada range acceptable, untuk grade scale dengan hasil C sedangkan pada adjective ratings dengan hasil good yaitu sebesar 76. Maka dari itu, Sistem informasi manajemen aset TI berhasil membangun sistem yang user-friendly dengan tingkat usability yang baik. Berdasarkan hasil pengujian black box, didapatkan hasil bahwa seluruh kebutuhan fungsional dari sistem yang dibangun telah terpenuhi dan berjalan dengan baik. Sistem informasi manajemen aset TI yang dibuat sudah memenuhi komponen usability yg sudah diujikan sehingga sistem tersebut layak untuk di operasikan/digunakan oleh anggota Bid TIK Polda Kepulauan Riau.
Perbandingan Kinerja Algoritma untuk Prediksi Penyakit Jantung dengan Teknik Data Mining
Authors: Derisma D
Published: September 2020

Heart disease is a disease that contributes to a relatively high mortality rate. The rate of human death caused by disease in the heart is a widespread problem in the world. The main objective of this study is to predict people with heart disease using the publicly available dataset in the UCI Repository with the Heart Disease dataset. To obtain the best classification algorithm is by comparing three Algoritma Naive Bayes, Random Forest, Neural Network algorithms, which are frequently used to predict people with heart disease. Comparison results show that Naive Bayes ' algorithm is a precise and accurate algorithm used to predict people with heart disease with a percentage of 83 %.
Impacto da consulta farmacêutica em pacientes polimedicados com alto risco cardiovascular
Authors: Reis Walleri Christini Torelli , Bernardo Camila dos Santos , Souza Thais Teles de , Bonetti Aline de Fátima , Favero Maria Luiza Drechsel
Published: September 2020

A ascensão dos serviços clínicos farmacêuticos possibilita que este profissional realize ações voltadas ao paciente, promovendo o uso racional de medicamentos e a melhoria da qualidade de vida. Estas ações podem ser realizadas a partir de consultas farmacêuticas, com a finalidade de otimizar a farmacoterapia do paciente e acompanhar periodicamente as suas condições de saúde a fim de avaliar a eficácia do tratamento. Objetivos: avaliar do impacto do serviço farmacêutico em pacientes polimedicados atendidos em ambulatório de hospital de grande porte. Métodos: foram coletados os dados obtidos das consultas realizadas durante seis meses no Ambulatório de Atenção Farmacêutica e estes dados foram analisados estatisticamente. Resultados: houve um aumento significativo do controle das morbidades entre a primeira e a segunda consulta, de 2,52 (±1,465), em média, para 2,95 (±1,519), p=0.003, indicando potencial benefício do cuidado farmacêutico sobre a saúde do paciente. Também foi observada uma constância na quantidade de queixas e no número de intervenções realizadas, reiterando a necessidade de acompanhamento continuado para a resolução de todos os problemas do paciente. Conclusão: o acompanhamento ambulatorial por farmacêutico clínico apresenta potencial para a obtenção de desfechos positivos na saúde do paciente.
Evaluation of hospital pharmacy services: an integrative review
Authors: Lima Rodrigo Fonseca , Toledo Maria Inês de , Naves Janeth de Oliveira Silva
Published: September 2020

Background: Pharmaceutical services performed in the hospital context have specific structure and processes, which should be continuously evaluated because they influence the results obtained.

Objective: To identify, describe and compare studies of evaluation of pharmaceutical services performed in the hospital context.

Methods: Integrative review of articles found in databases SciELO, LILACS, MEDLINE and IBECS, indexed in the period from 2000 to 2016, using the following descriptors: “Hospital Pharmacy Service” and “Evaluation“. The references were analyzed according to year, language, country of publication and type of study and classified according to their focus on the components of the hospital pharmacy service logic model that dealt with the management, selection, programming, acquisition, storage and distribution of medicines, information, pharmacotherapeutic, pharmacotechnical and teaching and research follow-up.

Results: Of the 25 publications, 16 (64%) were in the English language, of which 10 (40%) were in the United States; 17 (70%) studies were published from 2010 to 2016 and 13 (52%) were observational descriptive type. The most discussed component of pharmaceutical services was distribution logistics addressed in 15 publications (60%), followed by the management component addressed by 14 (56%) studies.

Conclusions: The publications emphasized the discussion on drug logistics. Only a few presented discussions on the impact of these services on health care, such as patient safety. Such studies can support the decision-making process and the formulation of strategies aimed at increasing the management capacity and the quality of the service provided.
A farmácia universitária no contexto das diretrizes curriculares do curso de farmácia (2017): um relato de experiência exitosa
Authors: Silvério Marcelo Silva , Corrêa José Otávio do Amaral
Published: September 2020

A Farmácia Universitária da UFJF desenvolve suas atividades de forma articulada com a rede de atenção à saúde no município de Juiz de Fora, através do Projeto Farmácia regional oeste. Este projeto permite cumprir alguns requisitos descritos nas novas DCN dos cursos de Farmácia, entre os quais se destaca a integração do curso de farmácia com o sistema local e regional de saúde do SUS e prática neste cenário. O projeto é fruto de uma cooperação entre a Universidade e a Prefeitura do município, para a dispensação dos medicamentos do componente básico da assistência farmacêutica aos usuários referenciados nas unidades básicas de saúde da região oeste. Esta cooperação define que a Farmácia Universitária ofereça a estrutura física, os recursos humanos e materiais, enquanto a Prefeitura disponibiliza os medicamentos para a dispensação. O projeto está implantado desde 2016 e atende, em média, 1600 usuários/mês. No âmbito do projeto, além da dispensação, são oferecidos outros serviços clínicos, são eles educação em saúde, revisão da farmacoterapia, acompanhamento farmacoterapêutico e conciliação medicamentosa. A Farmácia Universitária, através do Projeto, se caracteriza como cenário do SUS, é campo de estágio obrigatório para todos os alunos de graduação, campo de prática dos residentes farmacêuticos, além de desenvolver projetos de extensão e pesquisa. O projeto já permitiu uma economia no gasto com medicamentos no município, especialmente pela qualificação da assistência farmacêutica na região.
Profile of studies of potential drug interactions in Brazilian hospitals: an integrative review of the literature
Authors: Yamagata Adriana Tiemi , Barcelos Júnior Roberto Mauro Coelho , Galato Dayani , Meiners Micheline Marie Milward De Azevedo , Silva Emília Vitória Da
Published: September 2020

The risk of drug interaction (DI), especially in the hospital setting, increases along with the number of drugs used by the patient. Studies that evaluate drug interactions based on patient prescriptions are therefore useful to know this risk and guide strategies to improve drug use. The present study is aimed to identify studies that evaluated DI in patients of Brazilian hospitals. As of bibliographic search in several databases, we collected articles describing prescribing evaluations which focused on the analysis and identification of drug interactions in Brazilian hospitals. The search was conducted in 2017 and there was no restriction of publication time. Of a total of 273 articles retrieved, 23 were included for analysis. Most was published after 2010, and the predominant design was cross-sectional studies. The Micromedex® database was the most used to categorize the interactions, and midazolam and fentanyl was the most commonly reported potential DI in the studies. The results may guide futures research which should assess the real harm of IMP in patients and, then, promote the rational use of drugs.
Pharmacovigilance of quality deviations in the public healthcare system
Authors: Bitencourt Carolina Resende , Pádua Cristiane Aparecida Menezes De , Drummond Paula Lana De Miranda , Perini Edson
Published: September 2020

Drug quality deviation (DQD) is the disagreement with the parameters at the registration with after commercialization step. Pharmacovigilance programs should be notified of DQD to ensure drug efficacy and support patient safety.

Objective: To describe DQD from public healthcare system and its impact on the pharmaceutical service.

Methods: Descriptive analysis of DQD recorded at Belo Horizonte primary and secondary care facilities, from April to September 2016. Variables: Type of DQD, pharmaceutical product, therapeutic class, notifying health unit, risk classification, and reply of DQD notification. This analysis was described by measures of central tendency and dispersion.

Results: 329 DQD in 271 notifications were recorded leading to a loss of 9,311 preparations, representing on average 0.2% of the purchased lot. Most DQD were recorded at the primary health care level in solid preparations. Drug-related problems included deviations in package content (47%), package integrity (26%), label (5%), and pharmaceutical product itself (22%). Anti-infectives for systemic use (21%) and nervous system drugs (20,3%) were the main therapeutical classes. Approximately 70% of the DQD were classified as of intermediate risk. Drug suppliers replied 83.6% of notifications. No notification has been completely analyzed by the sanitary surveillance.

Conclusions: Pharmacovigilance is an important tool to minimize potential harm to the patient, since it prevents inappropriate medications from being made available for dispensing. DQD management also helps to minimize financial losses. The strengthening of this activity in all healthcare services also contributes to regulatory actions at the national level.
Pharmaceutical recommendations in a university hospital transplant unit
Authors: Pinheiro Maria K. , Chaves Elana F. , Oliveira Alene B. , Andrade Cinthya C. , Bastos Katherine X. , Guedes Marjorie M.
Published: September 2020

Introduction: The transplanted patient has a complex pharmacotherapy, with the pharmacist having an important role in the multidisciplinary team. Objective: To analyze the pharmaceutical recommendations made during the hospitalization of the patients in kidney and liver transplant units. Methods: This was a cross-sectional study in which pharmaceutical recommendations from May 2017 to April 2018 were collected from the records contained in the database of the Clinical Pharmacy Unit of a University Hospital in Fortaleza, Brazil. The recommendations were categorized and analyzed based on the classification used in the institution. Results: There were 1241 pharmaceutical recommendations involving 325 patients and 1466 medications. The recommendations were more frequent during liver transplantation (54.2%, n = 672), with dose adjustments (18.2%, n = 122) and dilution / reconstitution (9.8%, n = 66) being the most predominant types. In kidney transplantation, recommendations for education about medication use (17.6%, n = 100) and treatment adherence strategies (17.6%, n = 100) were the most predominant. The most frequent therapeutic classes were systemic antibacterials (31.2%, n = 458) and immunosuppressants (25.1%, n = 368). The acceptance rate of recommendations for kidney and liver transplantation were 95.1% (n = 541) and 95.4% (n = 641), respectively. Conclusions: The present study showed a high frequency of pharmaceutical recommendations and these results demonstrate that the detection of drug-related problems generates pharmaceutical recommendations that can contribute to the reduction of negative drug-associated results and increase patient safety.
Prescription for psychiatric patients in a Brazilian public hospital: cross-sectional study
Authors: Fernandes Maria R. , Lopes Laura J. , Rocha Milla P. , Almeida Laís P. , Ferreira Tânia R. , Rogerio Carolina B. , Bergamaschi Cristiane C.
Published: September 2020

Background: The growing use of psychotropic drugs has been attributed to a higher frequency of psychiatric disorders diagnosed, interaction of new drugs on the pharmaceutical market, and new therapeutic indications of existing drugs. Given this scenario, the adequacy of the use of psychotropic drugs needs to be analyzed considering the scientific evidences. Objectives: To assess the appropriateness of drug prescriptions used by psychiatric patients in a public hospital in Sorocaba, according to the best available scientific evidence, and to describe the profile of this population. Methods: This cross-sectional study collected data from clinical records of patients with psychiatric disorders hospitalized in the psychiatric sector of the Sorocaba Hospital Complex, state of São Paulo, Brazil, between August 2015 and December 2016. The outcomes measured were: inappropriate use, presence of contraindication and serious or contraindicated drug interactions, according to the information available on the Dynamed® and Micromedex® 2.0 databases. Results: Patients were predominantly adults, and diagnosed with paranoid schizophrenia or bipolar affective disorder. Antipsychotics, benzodiazepines, and lithium accounted for 84.0% (n=2,938) of the 3,500 drugs prescribed for mental disorders. There were 2,157 (61.6%) inappropriate prescriptions, of which 81.9% corresponded to antipsychotics, benzodiazepines, and lithium. There were 1,712 prescriptions with drug combinations that risked causing drug interactions, predominantly involving antipsychotic use (67.0%). Conclusion: The study revealed a high number of inappropriate prescriptions, pointing to a need for greater prescription adequacy to ensure effective safe treatment for psychiatric patients.
On uniform convergence of Fourier-Sobolev series
Authors: Shakh-Emirov Tadgidin
Published: September 2020

Let $\{\varphi_{k}\}_{k=0}^\infty$ be a system of functions defined on $ [a, b] $ and orthonormal in $ L ^ 2_ \rho = L ^ 2_\rho ( a, b) $ with respect to the usual inner product.
For a given positive integer $ r $, by $\{\varphi_{r,k}\}_{k=0}^\infty$ we denote the system of functions orthonormal with respect to the Sobolev-type inner product and generated by the system $\{\varphi_{k}\}_{k=0}^\infty$.
In this paper, we study the question of the uniform convergence of the Fourier series by the system of functions $\{\varphi_{r,k}\}_{k=0}^\infty$ to the functions $f\in W^r_{L^p_\rho}$ in the case when the original system $\{\varphi_{k}\}_{k=0}^\infty$ forms a basis in the space $L^p_\rho=L^p_\rho(a,b)$ ($1\le p$, $p\neq2$).
Candelaria como centro de distribución económica de los poblados guaraní-jesuíticos
Authors: Rojas Liliana Mirta
Published: September 2020

La reducción de Candelaria fue un pueblo como cualquiera de los 30 poblados guaraní-jesuíticos, con las mismas actividades económicas y los mismos problemas a resolver. Pero, al ser sede de la autoridad religiosa -allí se encontraba el Superior desde 1633- concentraba en ella la administración/distribución económica de los demás pueblos. El Superior se encargaba de todas las cuestiones económicas de las reducciones, junto a un grupo de ayudantes, y también administraba el sínodo correspondiente a los sacerdotes. Todas las transacciones económicas-compra, venta, vinculaciones con los Colegios y Oficios- eran controladas desde Candelaria y registradas cuidadosamente, y debían ser aprobadas por el Provincial instalado en Córdoba.
The effect of mindfulness-based stress intervention on neurobiological and symptom measures in adolescents with early life stress: A feasibility randomized controlled trial
Authors: Cohen Zsofia , Cosgrove Kelly T. , Akeman Elisabeth , Coffey Sara , Teague Kent , Hays-Grudo Jennifer , Paulus Martin P , Aupperle Robin , Kirlic Namik
Published: September 2020

Background Early life stress (ELS) has been linked to poor mental and physical health outcomes in adolescence and adulthood. Mindfulness reduces symptoms of depression and anxiety and improves cognitive and social outcomes in both youth and adults. However, little is known whether mindfulness can mitigate against the adverse neurobiological and psychological effects of ELS. This study aimed to examine the feasibility of conducting a group mindfulness intervention in adolescents with ELS and provide preliminary indication of potential effects on stress-related biomarkers and mental health symptoms. Methods Forty adolescents were randomized to receive either eight sessions of Mindfulness-Based Stress Reduction for Teens in group format (MBSR-T; n = 21) or Control (CTRL; n = 17). Outcomes were assessed at baseline and follow-up and included measures associated with neurobiological functioning (immune and endocrine biomarkers) and self-reported mental health symptoms. Linear mixed effects models were used to assess the effects of group and time on these outcome measures. ResultsSixteen of the 21 adolescents completed the intervention, attending an average of 6.5 sessions. The model examining depressive symptoms revealed a medium effect for symptom reduction [Cohen’s d = .69] in the MBSR-T relateive to CTRL groups.ConclusionsThis study demonstrated feasibilility of conducting a group-based MBSR intervention for adolescents with ELS. There was some evidence for efficacy on a symptom level with potential subtle changes on a biological level. Future larger studies are needed to determine the efficacy of group-based mindfulness interventions in this population.
RNA-seq analysis of bronchial organoids reveals ACE2 expression levels before and after SARS-CoV-2 infection
Authors: Chen Edward
Published: September 2020

The SARS-CoV-2 virus invades human cells via the angiotensin-converting enzyme 2 (ACE2)receptor. ACE2 expression in the lung cells creates a target for the SARS-CoV-2 virus, andconsequently infected individuals often see respiratory symptoms. Here, RNA sequencing(RNA-seq) datasets from in vitro human bronchial organoids (hBO) are analyzed to identifyunderlying gene expression changes as a result of an infection by SARS-CoV-2. Throughdifferential expression analysis, it was found that ACE2 expression levels did not changesignificantly after SARS-CoV-2 infection, but other genes that encode for major immunesignaling pathways were upregulated. This study can lend insight into potential targets for drugdevelopment and treatment for the COVID-19 disease.
Reputationsmanagement von öffentlichen und zivilgesellschaftlichen Organisationen
Authors: Willems Jurgen , Maier Florentine , Waldner Carolin
Published: September 2020

In den letzten Jahrzehnten hat das Streben nach Effizienz und Effektivität des Managements viele öffentliche und zivilgesellschaftliche Organisationen verändert. Viele öffentliche Organisationen – wie z.B. die deutschen öffentlichen Universitäten im oben beschriebenen Fall – haben sich im Zuge der New Public Management Reformen als eigenständige Einheiten neu organisiert. Eine solche Umstrukturierung hat die Chance erhöht, dass kontextspezifische Management- und Führungspraktiken eingeführt werden. So können die öffentlichen Universitäten nun beispielsweise freier über die Verwendung der Mittel entscheiden. Die Umstrukturierung hat jedoch auch die Notwendigkeit erhöht, dass die Organisationen ihre Leistungen managen und darüber berichten, um somit langfristig ihre Reputation gegenüber externen Stakeholdern aufzubauen. Dies können sie erreichen, indem sie das richtige Maß an Transparenz wahren und ihren Stakeholdern gegenüber Rechenschaft ablegen. Öffentliche Universitäten bemühen sich nun mehr um ihr Image, z.B. indem sie Hochglanzbroschüren drucken und ihre Jubiläen feiern. Gleichzeitig wird von ihnen mehr Transparenz bezüglich ihrer Prozesse und Wirkungsbereiche erwartet. Wenn zivilgesellschaftliche Organisationen für den Staat die Erbringung öffentlicher Leistungen übernehmen, dann geschieht dies zunehmend auf Basis von Leistungsverträgen mit komplexen Leistungs- und Zielvereinbarungen. Infolgedessen ist bei zivilgesellschaftlichen Organisationen die Notwendigkeit gestiegen, ihre Leistung, ihre Reputation, ihre Transparenz und ihre Rechenschaftspflicht gegenüber staatlichen Akteuren zu verwalten und zu steuern. Auch die Erwartungen privater Geldgeber/innen sind gestiegen, weil Skandale im Zusammenhang mit dem Missbrauch von Spendengeldern Spender/innen sensibilisiert haben (in Österreich z.B. der berüchtigteWorld Vision Skandal von 1998, der schließlich zur Einführung des österreichischen Spendengütesiegels führte). Aktuelle Trends in Richtung Venture Philanthropy und Impact Investment haben die Anforderungen privater Geldgeber/innen in Hinblick auf die Rechenschaftslegung von NPOs weiter erhöht.
Interelasi Masyarakat Adat Kajang dan Pola Kehidupan Modern
Authors: Nur Askar
Published: September 2020

Penelitian ini menganalisa tentang interelasi masyarakat adat Kajang dengan kehidupan modern dan menelaah korelasi dunia kesehatan modern dengan budaya masyarakat adat Kajang yang tidak menggunakan alas kaki dalam kehidupan sehari-hari. Hipotesis penelitian ini menunjukkan bahwa kehidupan modern dengan pola kehidupan masyarakat adat Kajang tanpa alas kaki memiliki kontradiksi. Di sisi lain dunia kesehatan modern menghendaki penggunaan alas kaki sebagai bentuk antisipasi dari pelbagai penyakit akan tetapi adat Kajang melalui fatwa adat Pasang ri’ Kajang menginstruksikan agar masyarakat adat menjaga jarak dari ihwal yang mengandung unsur modern termasuk penggunaan alas kaki. Pendekatan penelitian ini adalah pendekatan kualitatif deskriptif yang menggunakan teori sosiologi budaya Pierre Bourdieu dan menggunakan metode etnografi. Tujuan penelitian ini adalah mengungkapkan interelasi masyarakat adat Kajang dengan budaya tanpa alas kaki dan dunia kesehatan modern.
Multi-scale membrane process optimization with high-fidelity ion transport models through machine learning
Authors: Wessling Matthias
Published: September 2020

Innovative membrane technologies optimally integrated into large separation process plants are essential for economical water treatment and disposal. However, the mass transport through membranes is commonly described by nonlinear differential-algebraic mechanistic models at the nano-scale, while the process and its economics range up to large-scale. Thus, the optimal design of membranes in process plants requires decision making across multiple scales, which is not tractable using standard tools. In this work, we embed artificial neural networks (ANNs) as surrogate models in the deterministic global optimization to bridge the gap of scales. This methodology allows for deterministic global optimization of membrane processes with accurate transport models – avoiding the utilization of inaccurate approximations through heuristics or short-cut models. The ANNs are trained based on data generated by a one-dimensional extended Nernst-Planck ion transport model and extended to a more accurate two-dimensional distribution of the membrane module, that captures the filtration-related decreasing retention of salt. We simultaneously design the membrane and plant layout yielding optimal membrane module synthesis properties along with the optimal plant design for multiple objectives, feed concentrations, filtration stages, and salt mixtures. The developed process models and the optimization solver are available open-source, enabling computational resource-efficient multi-scale optimization in membrane science.
Cell Barrier Characterization in Transwell Inserts by Electrical Impedance Spectroscopy
Authors: Wessling Matthias
Published: September 2020

We describe an impedance-based method for cell barrier integrity testing. A four-electrode electrical impedance spectroscopy (EIS) setup can be realized by simply connecting a commercial chopstick-like electrode (STX-1) to a potentiostat allowing monitoring cell barriers cultivated in transwell inserts.Subsequent electric circuit modeling of the electrical impedance results the capacitive properties of the barrier next to the well-known transepithelial electrical resistance (TEER). The versatility of the newmethod was analyzed by the EIS analysis of a Caco-2 monolayer in response to (a) different membrane coating materials, (b) two different permeability enhancers ethylene glycol-bis(2-aminoethylether)-N,N,N’,N’-tetraacetic acid (EGTA) and saponin, and (c) sonoporation. For the different membrane coating materials, the TEERs of the standard and new protocol coincide and increase during cultivation, while the capacitance shows a distinct maximum for three different surface materials (no coating, Matrigel®, and collagen I). The permeability enhancers cause a decline in the TEER value, but only saponin alters the capacitance of the cell layer by two orders of magnitude. Hence, cell layer capacitance and TEER represent two independent properties characterizing the monolayer. The use of commercial chopstick-like electrodes to access the impedance of a barrier cultivated in transwell inserts enables remarkable insight into the behavior of the cellular barrier with no extra work for the researcher. This simple method could evolve into a standard protocol used in cell barrier research.
Assessment of a Short, Focused Training to Reduce Symptoms of Cybersickness
Authors: Preciado Cristian , Starrett Michael James , Ekstrom Arne
Published: September 2020

Past reports have suggested that active visual training in virtual reality (VR) can reduce symptoms of cybersickness. Here, we adapted such a protocol to a computer-based version and compared it with a passive exposure control condition. We employed heart rate and other subjective predictors of cybersickness to try to predict the efficacy of the intervention as well as likelihood of drop out. While we found a significant decrease in heart rate across sessions, the intervention we employed did not appear to be effective at reducing cybersickness or dropout. However, a heart rate increase of 15.5 bpm from baseline, nausea self-report of 4.5 on a scale of 1-10, and dizziness self-report of 5.5 on a scale of 1-10 predicted an equal probability of experiment dropout, independent of whether participants were in the experimental or control intervention condition. Our findings suggest that a single immersion of visual training in VR or passive VR exposure may not be sufficient to provide adaptation for VR. At the same time, our findings bolster past reports suggesting the value of employing heart rate monitoring, rather than subjective reports, to monitor the onset of cybersickness.
Integrating social and cognitive aspects of belief dynamics: Towards a unifying framework
Authors: Galesic Mirta , Olsson Henrik , Dalege Jonas , van der Does Tamara , Stein Daniel L.
Published: September 2020

Belief change and spread have been studied in many disciplines-- from psychology, sociology, economics and philosophy, to computer science and statistical physics-- but we still do not have a firm grasp on why some beliefs change and spread easier than others. To fully capture the complex social-cognitive system that give rise to belief dynamics, we need to integrate the findings of these disciplines into a single framework. Communication between disciplines is limited, and there is a lack of theoretical comparisons and empirical tests of the many different models of belief dynamics. Here we first review insights about structural components and processes of belief dynamics studied in different disciplines, focusing particularly on previously neglected but important areas such as cognitive representations and strategies used to integrate information. We then outline a unifying framework that enables theoretical and empirical comparisons of different belief dynamic models. The framework is quantified using a statistical physics formalism, grounded in cognitive and social theory as well as empirical observations. We show how the framework can be used to integrate numerous previous models and develop a more comprehensive science of belief dynamics.
Robust Machine Learning for Treatment Effects in Multilevel Observational Studies Under Cluster-level Unmeasured Confounding
Authors: Suk Youmi , Kang Hyunseung
Published: September 2020

Recently, machine learning (ML) methods have been used in causal inference to estimate treatment effects in order to reduce concerns for model mis-specification. However, many ML methods require that all confounders are measured to consistently estimate treatment effects. In this paper, we propose a family of ML methods that estimate treatment effects in the presence of cluster-level unmeasured confounders, a type of unmeasured confounders that are shared within each cluster and are common in multilevel observational studies. We show through simulation studies that our proposed methods are robust from biases from unmeasured cluster-level confounders in a variety of multilevel observational studies. We also examine the effect of taking an algebra course on math achievement scores from the Early Childhood Longitudinal Study, a multilevel observational educational study, using our methods. The proposed methods are available in the CURobustML R package.
Altercentric cognition: how others influence our cognitive processing
Authors: Kampis Dora , Southgate Victoria
Published: September 2020

Humans are ultra-social, yet, theories of cognition have often been occupied with the solitary mind. Over the last decade, an increasing volume of work has revealed how individual cognition is influenced by the presence of others. Not only do we rapidly identify others in our environment, but we align our attention with their attention, which influences what we perceive, represent and remember; even when our immediate goals do not involve coordination. The present article refers to the human sensitivity to others and to the targets and content of their attention as ‘altercentrism’; and aims to bring seemingly disparate findings together, suggesting that they are all reflections of the altercentric nature of human cognition.
Pemanfaatan Media Pembelajaran Online untuk Meningkatkan Pembelajaran Mandiri Di Masa New Normal
Authors: Sebayang F Ari Anggraini , Saragih Ordekoria , Hestina Hestina
Published: September 2020

Pandemi Covid-19 yang telah terjadi beberapa bulan terakhir berdampak terhadap pembelajaran siswa yang awalnya diselenggaran secara luring menjadi daring. Sebagai langkah antisipasi, pemerintah telah bekerja sama dengan berbagai pengelelola situs belajar daring agar memberikan akses gratis kepada siswa. Akan tetapi kompensasi akses pada sumber-sumber belajar online ini masih belum dimanfaatkan secara maksimal . Oleh karena itu, pengabdian masyarakat ini dilakukan untuk mensosialisasikan pemanfaatan media pembelajaran online untuk meningkatkan pembelajaran mandiri di masa new normal. Pengabdian ini dilakukan kepada anak-anak di Panti Asuhan Yayasan Talenta Delpita Medan. Adapun metode pelaksanaan pengabdian kepada masyarakat ini dilakukan dalam tiga tahapan, yaitu 1) persiapan; 2) kegiatan sosialisasi; dan 3) evaluasi. Berdasarkan hasil pengamatan dan evaluasi, pengabdian kepada masyarakt ini mampu memberikan pengalaman belajar yang berbeda kepada anak. Pemanfaatan media belajar online juga meningkatkan antusiasme dan motivasi belajar anak. Selain itu, motivasi anak untuk belajar secara mandiri juga meningkat dengan memanfaatkan sumber-sumber belajar yang tersedia di internet.
Training of the future vocational education teachers in the conditions of student-centred learning and teaching
Authors: Melnyk Taras , Dobroskok Iryna
Published: September 2020

The article reveals the theoretical aspects of the future vocational education teachers' training in the conditions of student-centred learning and teaching, which is based on the principles of the flexibility of individual educational trajectories and different methods usage, students' autonomy support, mutual respect of teachers and students and the respect to the diversity of students and their needs. The purpose of the article is to highlight and analyze the peculiarities of preparation of future vocational education teachers in the conditions of student-centred learning and teaching. In accordance with the purpose and the set objectives, such theoretical methods of research were applied as an analysis, a synthesis and the generalization of scientific-pedagogical literature and normative-legal documents. The author believes that the future vocational education teachers’ training in a student-centred setting is a complex task according to the ESG recommendations. The study identifies the positive features of a student-centred approach, as well as the possible risks; characterizes and analyzes the key principles of the European Standards and Guidelines (ESG) on Quality Assurance in the European Higher Education Area (EHEA) in terms of the specificities of the training system for future vocational education teachers. Moreover, it defines that providing sufficient feedback from students, forming assessment criteria based on the creative display of acquired knowledge and skills, rational lesson planning, adherence to the “lifelong learning” principle, and promoting self-examination among teachers and students are the key components of implementing the student-centred learning and teaching principles. The author made a conclusion that student-centred learning and teaching contributes to the realization of intellectual, cultural and emotional potential, creates the conditions for students’ self-expression and self-identification, promotes the democratic and humanistic values of institutions of higher education (IHE) as important public institutions and, having a positive impact on the quality of training, creates a springboard for realizing the educational process participants’ potential on the basis of proactivity and common opinion.
Higher School Teacher’s Integrated Self-Development
Authors: Vaintraub Mark
Published: September 2020

The article deals with the problem of the integrated self-development of the personality, the need for the development of methodological foundations for the personal and professional self-development of higher education teachers. An attempt to create a model (tree) of the personality’s integrated self-development was made on the example of a higher education teacher. The «tree’s root», depicted below the crown, is a necessary basic condition for a self-development, its base area of an actual self-development; among its indicators should be noted here the teacher’s spirituality and moral maturity, without which a successful self-development may not be carried out. The «tree’s body», depicted in the middle of the model, is a system of interconnected structural elements of the higher education teacher’s integrated self-development. The «tree's top» is the continuation of creative self-realization of abilities according to other goals and tasks after the completion of the previous ones. The emphasis is on the introduced concepts of «integrated self-development of a personality», «integrated self-development of a higher education teacher»; the directions that contribute to the continuation of self-development of the formed personalities (higher education teachers), and encourage them to creativity.
The researches of the most well-known scientists concerning the personality’s self-development, that does not give an opportunity to extinguish creativity, improves physical, intellectual and moral values, promote interest in life and self-perfection, are analyzed.
The article presents the examples of modern prominent Ukrainian and foreign scholars-teachers who, thanks to their integrated self-development, continue their creative search and improve their abilities in various spheres of life.
The author notes that it is the absence of the extinction of active social and personal activities, the integrated self-development of a personality, that result in its no fading, so that a person retains a creative potential throughout its life, the realization of all its abilities, maintains a high quality of life. The author of the article gives an example of the considered integrated development of a personality, which is the outstanding Ukrainian scientist, scholar Ivan Andriiovych Ziaziun.
The article has a conclusion that, regardless of the sphere of activity, such people continue to be developed, although they have had enormous achievements and regalia; they have had an integrated self-development of various manifestations of their abilities and qualities, an internal need, which required an every day building of their vital reality and transfer their experience to others.
Educational and methodological support of the future mechanical engineering specialists training for the labour protection professional activity
Authors: Dembitska Sofiia
Published: September 2020

The article is devoted to the substantiation of the directions of improving the educational and methodical support of the future mechanical engineering specialists’ training for labour protection professional activity.
The aim of the article is to identify areas for improving the educational and methodological support of the future mechanical engineering specialists’ training for labour protection professional activity. The author uses such research methods as analysis of scientific literature, generalization, comparison, systematization, abstraction and methods of mathematical statistics.
The benefit of the study is that the ways of improving the educational and methodological support of labour protection disciplines and its structure are defined: the target block (contains the purpose and tasks of a discipline study), the normative block (contains information about the number of credits in the context of classroom and independent work, content modules, structural and logical place of a discipline in the educational training of specialists, etc.), the information block (contains training material in a modular structure), the methodical block (contains the characteristics of forms, methods and tools that provide future mechanical engineering specialists by the labour protection competencies’ forming), the control unit (contains materials for determining the level of labour protection competence) and the resource unit. Moreover the directions of improving teaching labour protection disciplines are defined and reflected in the educational and methodological support of the future mechanical engineering specialists’ training for labour protection professional activity, they are: motivation provision, individual tasks definition, activation of students' educational activity; and the peculiarities of educational and methodological support of the future mechanical engineering specialists’ training for labour protection professional activity are characterized.
Analisis Quality Function Deployment di Setiap Service Area PT Garuda Indonesia (Persero)
Authors: Puspita Mutiara Eka
Published: September 2020

Industri penerbangan dunia tengah mengalami tantangan yang hebat selama dekade terakhir. Menghadapi isu global tersebut, negara-negara Asia Tenggara mencoba untuk menerapkan kebijakan liberalisasi penerbangan ASEAN (ASEAN Open Sky) agar dapat menciptakan kompetisi yang ketat antar maskapai untuk meningkatkan keunggulan bersaing. Kebijakan ASEAN Open Sky tersebut menyebabkan banyak maskapai asing, tidak terkecuali Singapore Airlines, menjadikan Indonesia sebagai target pasar utama. Oleh sebab itu, Garuda Indonesia perlu melakukan perbaikan disegala bidang mengingat pesaing utama pada ASEAN Open Sky, Singapore Airlines, dinilai memiliki performansi yang sangat baik di mata dunia. Metode untuk membantu melakukan perbaikan kualitas adalah Quality Function Deployment dengan alat yang digunakan House of Quality (HOQ). Dengan HOQ dapat dihasilkan rancangan layanan baru berbasis pelanggan yang barmanfaat bagi perbaikan kualitas layanan demi keunggulan bersaing. Tujuan penelitian ini adalah untuk (1).Mengetahui tingkat kepuasan pelanggan PT Garuda Indonesia (Persero) dibandingkan dengan Singapore Airlines dan tingkat kepentingan atribut layanan yang terdapat pada HOQ; (2).Mengetahui bagaimana rancangan perbaikan layanan dengan HOQ PT Garuda Indonesia yang sesuai dengan kebutuhan dan keinginan pelanggan serta kemampuan perusahaan. Hasil penelitian menyatakan bahwa responden lebih puas pada pelayanan Singapore Airlines dengan nilai rata-rata 3.54 dibandingkan Garuda Indonesia dengan nilai rata-rata 3.0683 dari skala 4. Sesuai hasil rancangan House of Quality, layanan yang menjadi prioritas dilakukan perbaikan dan peningkatan kualitas berdasarkan nilai absolute weight adalah (1).penanganan bagasi; (2).kehandalan layanan ticketing; (3).kebersihan dan fungsi toilet; (4).ketanggapan karyawan dalam penanganan keluhan pelanggan; dan (5).kesesuaian harga yang ditetapkan dengan service yang diterima. Sedangkan prioritas utama karakteristik teknik yang dapat dilakukan perusahaan adalah (1).pemilihan mitra outsource yang terbaik; (2).implementasi boarding management berdasarkan rekomendasi Skytrax; (3).peningkatan attitude karyawan untuk bersikap empati dan ramah; (4).penyediaan staf yang memadai; serta (5).penentuan & pemenuhan service standar bagi frontliner.Â Kata Kunci : Quality Function Deployment, House of Quality, Kualitas
Manfaat Faktor Konversi untuk Pengujian Kuat Tekan Paving-Block
Authors: Yanita Rachmi , Andreas Gufran
Published: September 2020

Paving-block banyak digunakan sebagai material konstruksi sehingga kekuatan dan mutu harus sesuai dengan spesifikasi yang ditentukan. Pengujian paving-block dilakukan sesuai standar SNI 03-0691-1996 yang mengacu kepada SNI 03-0348-1989. Standar yang bersifat umum mengakibatkan perbedaan interpretasiÂ  sehingga pelaksanaannya menjadi tidak standar. Adanya kebutuhan pihak industri konstruksi bahwa pengujian kualitas material dapat diperoleh hasilnya dengan cepat, harus juga diantisipasi oleh standar pengujian, Â dengan tetap berpegang pada norma akademik. Pengujian langsung benda uji paving-block pada alat tekan standar ASTM C39 tanpa faktor konversi tidak diperkenankan, sehingga diperlukan besaran faktor konversi yang di standarkan. Oleh sebab itu dilakukan penelitian besaran faktor konversi bentuk benda uji standar paving-block dengan ketebalan 6 cm terhadap benda uji kubus 15x15x15 cm. Hasil kajian penelitian iniÂ  menunjukkan bahwa pengujian langsung sampel paving-block tanpa penggunaaan faktor konversi akan menghasilkan kuat tekan yang lebih besar dari yang seharusnya atau seharusnya tidak memenuhi spesifikasi. Hal ini merupakan hal yang merugikan dan dapat membahayakan bagi industri konstruksi. Ketentuan besaran faktor konversi dibutuhkan untuk pengujian kuat tekan paving-block dengan alat tekan standar ASTM C39 sehingga memberikan nilai kuat tekan yang dapat dipertanggungjawabkan.Â Kata Kunci : Uji tekan paving-block, waktu uji cepat, faktor konversi
Kualitas Barrier Kemasan Fleksibel Berbasis Metalized Film untuk Produk Pangan
Authors: Nurani Darti , Sukmadi Indrati , Hidayat Nahrul
Published: September 2020

Saat ini kemasan fleksibel berbasis metalized film cukup banyak jenisnya di pasaran dan umumnya digunakan oleh industri pangan untuk mengemas produk pangan kering (contoh: wafer, biskuit, sereal kopi bubuk, permen dan lain-lain). Namun, untuk beberapa jenis kemasan fleksibel tersebut masih belum diketahui kualitas perlindungannya terhadap produk, sehingga dikhawatirkan umur simpan produk pangan tidak sesuai dengan yang diinginkan. Penelitian ini bertujuan untuk mengetahui pengaruh struktur laminat pada kualitas barrier kemasan fleksibel berbasis metalized film. Penelitian ini dibagi dalam dua tahap. Rancangan percobaan pada penelitian tahap pertama adalah Rancangan Acak Lengkap (RAL), satu faktor. Faktor A adalah jenis metalized film yang terdiri atas tiga taraf: a1= VMPET film 12 Âµm, a2= VMCPP film 25 Âµm dan a3= VMCPP film 35 Âµm. Analisis dilakukan terhadap nilai laju permeabilias uap air, dengan pengulangan sebanyak 10 kali. Rancangan percobaan pada penelitian tahap kedua adalah Rancangan Acak Lengkap (RAL), satu faktor. Faktor A adalah jenis kemasan fleksibel berbasis metalized film yang terdiri atas enam taraf: a1 = PET 12 Âµm /VMPET 12 Âµm /PE 20 Âµm /LLDPE 25 Âµm,Â  a2 = OPP 20 Âµm /VMPET 12 Âµm /CPP 35 Âµm, a3 = PET12 Âµm /VMCPP 25 Âµm, a4 = OPP 20 Âµm /VMCPP 25 Âµm, a5 = PET 12 Âµm /VMCPP 35 Âµm dan a6 = OPP 20 Âµm /VMCPP 35 Âµm. Analisis dilakukan terhadap nilai laju permeabilitas uap air, dengan pengulangan sebanyak 10 kali. Hasil analisis laju permeabilitas uap air diolah menggunakan software Statistical Product and Service Solution (SPSS). Berdasarkan penelitian ini diperoleh hasil bahwa terdapat pengaruh struktur laminat pada kualitas barrier kemasan fleksibel berbasis metalized film. Kemasan fleksibel dengan spesifikasi PET12/VMPET12/PE20/LLDPE25 memiliki nilai laju permeabilitas uap air yang terbaik, yaitu sebesar 0.1430 g/m2/hari.Â Kata kunci: metalized film, kemasan fleksibel berbasis metalized film, permeabilitas uap air