bluuebunny/crossref_metadata_2025 huggingface dataset:
PERAN KOMISI PENGAWAS PERSAINGAN USAHA SEBAGAI WASIT SEKALIGUS HAKIM DALAM EKONOMI
Authors: Dewi Ratna , Timori Helmin Porang , S Moh. K. Aripin , Zakariya Ali , Putri Audrey Aulia , Taena Markus , Ramadhanty Andiera Eko
Published: January 2025

The Business Competition Supervisory Commission (KPPU) is a state institution that has a crucial role in maintaining balance and fairness in the dynamics of the Indonesian market. As a supervisor of business competition, KPPU functions as a referee who ensures that all business actors play by the same rules. Its main task is to prevent monopolistic practices, cartels, and other unfair competition that can harm consumers and hinder economic growth. The purpose of this study is to determine the problems faced by KPPU in carrying out its duties. The research method used is normative juridical. The data analysis is by using the Qualitative method. The results of the study are that in carrying out its duties, KPPU still faces a number of challenges. One of the main challenges is the increasing complexity of business competition cases, especially along with the development of technology and globalization. In addition, KPPU also needs to continue to improve the capacity of its human resources in order to handle cases more quickly and effectively. The conclusion is that KPPU needs to continue to make various efforts, such as strengthening coordination with related institutions, increasing public awareness of the importance of healthy business competition, and developing information technology to support the supervision process. KPPU also needs to continue to conduct studies and research to understand the latest developments in market dynamics and business competition. In the increasingly developing digital era, KPPU also needs to pay attention to the development of digital technology and its impact on business competition. For example, KPPU needs to anticipate the potential for monopolies or cartels in digital platforms, and ensure that digital innovation does not hinder healthy competition. By carrying out its dual role as referee and judge effectively, KPPU can contribute significantly to realizing a fair, efficient, and competitive Indonesian economy.
PELAKSANAAN GANTI RUGI SENGKETA TANAH DALAM PROYEK INFRASTRUKTUR PEMBANGUNAN JALUR KERETA CEPAT JAKARTA-BANDUNG
Authors: Sukmaningrum Deva , Soediro
Published: January 2025

The purpose of this research is to provide an explanation of the implementation of compensation in infrastructure projects. The research methods used are normative and empirical juridical legal research methods. Land is a basic human need that is very important in human life. Indonesia's population growth is increasing rapidly, so there is little land available to meet the needs of the community. However, the government must carry out development to provide adequate infrastructure for the community to better support their lives. In carrying out development, especially for the public interest, it is often necessary to use land from the community. The community land can be used for development purposes through the process of land acquisition for public interest. During the land acquisition process, the most important thing is the agreement between the agency that needs the land and the landowning community to determine the form and amount of compensation. Compensation is a proper and fair replacement to the rightful party in the land acquisition process. Land acquisition is very important for infrastructure development, one of which is the construction of a railway line. The government has the legitimacy to take over land owned by individuals or legal entities for the construction of the Jakarta-Bandung High Speed Railway. The construction of the Jakarta-Bandung High Speed Railway is a public project that requires a land acquisition process. The land acquisition process can run smoothly with appropriate compensation.
TINJAUAN PROSES PERUBAHAN NAMA DI PENGADILAN SEBAGAI HAK INDIVIDU YANG DI CATATKAN NEGARA
Authors: Utomo Abdulah Rafi , Samhudi Gamalel Rifqi
Published: January 2025

Name change is an individual right guaranteed by the government, allowing every citizen to manage their personal identity according to their wants and needs. This process must be carried out through formal legal procedures, as stipulated in Law Number 24 of 2013 concerning Population Administration. This study aims to analyze the implementation of name change procedures in Indonesia, focusing on Stipulation number 14/Pdt.P/PN Pbg, which rejected a name change application due to non-compliance with legal procedures. The research method used in the preparation of this study is the normative juridical approach, which specifically focuses on the analysis of norms or the application of principles in applicable law. Based on Law Number 24 of 2013, name changes require a stipulation from the district court according to the applicant's domicile. In addition, Presidential Regulation No. 96/2018 stipulates that the recording of a name change must be accompanied by a copy of the court decision, an extract of the civil registration certificate, a family card, an electronic identity card, and travel documents for foreign nationals. The applicant's application in Stipulation No. 14/Pdt. P/PN Pbg was rejected in relation to the name change application due to non-compliance with applicable legal procedures. The applicant had made several identity changes at the Population and Civil Registration Office without going through the court process, which clearly violated the existing provisions.
PERLINDUNGAN HUKUM BAGI DRIVER GRAB YANG MENGALAMI PESANAN FIKTIF PADA ERA GIG ECONOMY
Authors: Ery Charmelita Raska  , Wardani Susilo
Published: January 2025

This research aims to analyze the legal relationship between Grab drivers and Grab platform in the context of gig economy in Banyumas Regency, as well as legal protection for drivers who experience fictitious orders. This research uses normative juridical and empirical juridical methods. The research data includes primary data from direct interviews with several drivers in Banyumas Regency and supported by secondary and tertiary data. The data analysis method uses qualitative analysis method. The first research result shows that the relationship between the driver and the platform arises due to a partnership agreement that gives birth to balanced rights and obligations between the parties. In practice, the relationship between drivers and platforms looks like a working relationship where there are elements of orders, wages, and work as well as relationships such as superiors and subordinates that create imbalances in the existing partnership agreement. So it looks like a pseudo-partnership relationship. When viewed in Regional Regulation Number 5 of 2021 concerning Creative Economy Development, Grab drivers are included in the type of freelancers with a partnership pattern system using a profit-sharing system regulated in article 4 and article 33. However, these rules still do not provide adequate legal protection for online ojek drivers. The second research result, legal protection for drivers who experience fictitious orders is still limited. The Grab platform provides protection by providing a reimbursement mechanism, which has been stated in the partnership agreement between the driver and the Grab platform. The unclear legal relationship between Grab drivers and the platform in the Gig Economy era in Banyumas causes weak protection for drivers who experience fictitious orders.
PENGELOLAAN DAN PERIZINAN PARIWISATA GUNUNG GEULIS LEARNING CENTER DENGAN GOOD CORPORATE GOVERNANCE SEBAGAI SARANA KESEJAHTERAAN MASYARAKAT
Authors: Kusuma Ibnu , Samhudi Gamalel Rifqi
Published: January 2025

Tourism plays an important role in improving the economy and welfare of the community, especially through the development of tourist destinations in Indonesia that are rich in culture, history, and natural beauty. This research analyzes tourism management and licensing at the Gunung Geulis Learning Center in Jipang Village, Brebes Regency, as an effort to improve the welfare of the local community. The main focus of this research is on the potential for tourism development and management in Good Corporate Governance so that it can be applied accordingly so that inhibiting factors can be overcome such as management and facilities that must be fulfilled and the welfare of the surrounding community through community participation and government support. This researcher uses a normative juridical approach method intended as an effort to observe the problem being investigated with legal characteristics, books, laws and regulations, and other related documents. The results of this study can be input for the government and tourism managers in order to apply the principles of Good Corporate Governance.
PERAN NOTARIS, PPAT, DAN BANK DALAM PENDAFTARAN HAK TANGGUNGAN ELEKTRONIK ATAS KREDIT MODAL USAHA
Authors: Pangesti Shinta , Yovieta Aprillia
Published: January 2025

In fact, the registration of mortgage rights after the implementation of business capital credit is an important stage. From the credit agreement to the registration of mortgage rights, it is inseparable from the role of a Notary, PPAT, and Bank. Because electronic deletion of mortgage rights has been implemented, it is also necessary to understand the differences between manual and electronic deletion of mortgage rights. This study aims to analyze the role of Notaries, PPATs, and Banks in the registration of HT-el for business capital credit and to analyze the differences between manual and electronic deletion of mortgage rights. The legal research used is normative legal research with a statutory approach. Primary data was obtained from interviews with two informants who were determined by purposive sampling, while secondary data was obtained through literature studies. In placing mortgage rights on business capital loans, the Notary, PPAT and Bank each have an important role. Starting from receiving the bank order letter to the issuance of the mortgage certificate, each holds an irreplaceable role and responsibility. Several differences were also found between manual and electronic deletion of mortgage rights, including: legal basis, method of implementation, role of PPAT, time limit, and final product.
Performance of Muhammadiyah Hospital as Social Entrepreneurship Organization: The Role of Leadership Effectiveness
Authors: Indra Nur Fauzi  , Fendy Suhariadi  , Albertus Eka Putra Hariyanto  , Erlyn Yuly Astuti
Published: January 2025

Background: Muhammadiyah is one of the largest religious organizations in Indonesia which owns and manages the largest non-profit hospitals for more than a hundred years. Muhammadiyah Hospital is a model of social entrepreneurship organization (SEO). Studies related to the performance of Muhammadiyah hospital organizations and their relationship with several other related variables have not been widely conducted and have focused more on Muhammadiyah's philanthropic activities and roles, Muhammadiyah's history in the field of health services, and the ethics of Muhammadiyah's health service. Therefore, this research aims to explore the relationship of variables Servant Leadership, Managerial Cognitive Capability, and Emotional Regulation to shape Organizational Performance (OP) with intermediate variable: Leadership Effectiveness in Muhammadiyah Hospitals. This research utilizes primary data which was collected through phone-call surveys with 443 top and middle management respondents at 111 Muhammadiyah Hospitals in Indonesia. The data was collected by trained and experienced Enumerators using structured questionnaire designed specifically for each type of respondents.
Methods: The study utilizes Structural Equation Modelling (SEM) methods using Maximum Likelihood Estimation. The method is used to analyze the influence of variables Servant Leadership, Managerial Cognitive Capability, and Emotional Regulation: Improving and Worsening (IMP and WOR) on Organizational Performance (OP) with Leadership Effectiveness as a mediator.
Results: The study results found that Servant Leadership, Managerial Cognitive Capability, and Emotional Regulation: Improving (IMP) have a positive effect on Leadership Effectiveness. The increasing Servant Leadership, Managerial Cognitive Capability, and Emotional Regulation: Improving (IMP) will increase Leadership Effectiveness. Meanwhile, Emotional Regulation: Worsening (WOR) has a negative effect on Leadership Effectiveness. Increasing Emotional Regulation: Worsening (WOR) will reduce Leadership Effectiveness. The analysis results show that Leadership Effectiveness variable directly affects Organization Performance positively, in terms of the effect of Leadership Effectiveness as a mediate variable.
Conclusion:This research concludes that leadership effectiveness play an important role in the cognitive abilities of hospital directors in driving hospital performance and the hospital director's cognitive ability is the key to strengthen leadership effectiveness. Considering limitations of this research, future studies should employ a-mix method of quantitative and qualitative data collection technique to bring deeper analysis results, as well as include diverse leadership types other than servant leadership to explore their relationship with the organization performance.
Demographic Influences on the Adoption of Herbicides in Indian Agriculture: A Study of Soybean and Sunflower Farmers
Authors: Jain Akhilesh , Mathur Aditi , Jain Lokesh Kumar
Published: January 2025

The study has conducted to identify the factors influencing the adoption of new molecules as an input for sustainable and viable agriculture. The adoption of herbicides reduces the drudgery in terms of manpower utilized in manual hoeing to reduce the weed infestation. The inequality in adoption behavior of farmers variably dependent on personnel as well as social factors however fast adoption is get momentum by seeing by doing or demonstrations conducted by manufactures. The study was statistically analysed using chi-square test. The sample size was 459 in eight districts of five states of India. The study has shown that a farmer's adoption behavior is significantly influenced by their age, level of education, and amount of land they own, but gender has no discernible effect. Also, here emphasize the advancements in adoption of herbicides for an alternate approaches in management of resources which are particularly valuable to agroecology, policymakers, and stakeholders.
On Some Results involving many variable functions of Hardy Integral Inequalities
Authors: Oluwatoyin Yisa , Iluno Christiana , Kamilu Rauf
Published: January 2025

Inequalities involving superquadratic and subquadratic functions of independent interest are established for refined Hardy-type inequalities using fairly elementary analytical ideas. The consequences of our main results are derived and the corresponding proofs are presented.
Dynamics of Predator-prey Interactions in Sharp Tooth Catfish (Clarias gariepinus; Burchell, 1822) and Carp Fingerlings (Labeo bata; Hamilton, 1822) with Special Reference to the Development of Anti-Predatory Strategies
Authors: Chakraborty Deep Chandan
Published: January 2025

This study explores the dynamics of predator-prey interactions and functional response of Clarias gariepinus (African Magur/Sharptooth Catfish - predator) and of Labeo bata (Carp fingerlings - prey). Author investigated the behavioral patterns of both species in isolation and during encounters, exploring the impacts of predator size, prey-predator ratio, encounter duration and placement of separators on anti-predatory strategies. Results indicated that prey behavior is influenced by predator presence, with crowding, hiding, and inspection emerging as key anti-predatory strategies. The development and intensity of these strategies are intricately linked to prey-predator ratio, size difference, and encounter duration. Notably, larger predators trigger more pronounced anti-predatory responses in preys, while high prey composition motivates individuals to inspect predators, conveying fearlessness and fitness. Findings provide valuable insights into the evolution of predator-avoidance behaviors in prey species, sheds light on the complex dynamics governing predator-prey interactions in aquatic ecosystems.
Current repertoire trends of Russian opera theaters (a review of the premieres of the 2023/2024 season of the Moscow opera)
Authors:   Moscow City Pedagogical University, Artemova Evgenia G.
Published: January 2025

Using the example of a review of new productions of the 2023/2024 season of three
Moscow musical theaters, the article undertakes an analytical study of modern repertoire trends in
Russian opera houses. The author’s focus includes premiere performances of the Helikon OperaThe
Stanislavski and Nemirovich-Danchenko Moscow Academic Music Theatre and the New Opera,
in particular, the following productions are considered: "Cherevichki", "Emperor of Atlantis" and
"Madama Butterfly" at the Helikon Opera, "The Tsar’s Bride", "Not Only Love" and "Mermaid" at the
MAMT K. S. Stanislavsky and Vl.I. Nemirovich-Danchenko, "War and Peace. Natasha and Andrey",
"The Flying Dutchman", "The Postman from Longjumeau" at the New Opera.
The analysis of new opera productions, in which theaters are equally turning to domestic and foreign,
modern and classical opera, shows that the course today is predominantly focused on a multidirectional
repertoire, in which military themes occupy a separate place. The exception was the Stanislavsky and
Nemirovich-Danchenko MAMT, which presented domestic operas during the past season; in general,
they began to occupy a more prominent place on Russian music and theater stages. The premiere
performances demonstrate the tendencies to discover new points of perception of well­known opera
masterpieces, the desire to discover little-known ones and to revive long-forgotten opuses.
«Душевный тюремщик» Иоганна Непомука Нестроя и стереотипы романтического театрального искусства
Authors:   Gnesin Russian Academy of Music, Vlasov Alexei A.
Published: January 2025

The article is devoted to the consideration of the main plot motifs in the parody by
the Austrian playwright Johann Nepomuk Nestroy "Der gefühlvolle Kerkermeister oder Adelheid
die verfolgte Wittib" (1832). Based on the pantomime ballet "Adelheid von Frankreich" by Louis
Henri — Cesare Puni.
The analysis of the play by J. N. Nestroy allowed to reveal in the literary text a number of
plot motifs characteristic not only for ballet performances of the first third of the XIX century,
but also for a number of European operas of the pre-Romantic and Romantic era аnd to
conclude that Nestroy’s play is a set of common plot and dramaturgical clichés, brought to the
point of absurdity by the playwright; the object of parody and satire is not so much a specific
ballet by Henri-Pounis as a general corpus of musical and theatrical texts of the first third of the
19th century.
When considering the musical component of the performance, its specificity and difference
from Nestroy — Muller’s operatic parodies is noted.
M. I. Glinka’s operas in Siberia: musical-critical reception in the regional press of the last third of the XIX century
Authors:   M. I. Glinka Novosibirsk State Conservatory, Svetlova Olga A.
Published: January 2025

The article traces the history of the performance and staging of M. I. Glinka’s operas in
the Siberian cities of Tobolsk, Tomsk and Irkutsk in the last third of the XIX century through the prism
of musical and critical reception. The material is provided by the most representative publications
in the regional press — the government newspaper "Tobolsk Provincial Vedomosti" and private
publications "Siberian Bulletin" and "Eastern Review".
Reviews of concerts are considered, in which solo and choral fragments of Glinka’s operatic
masterpieces were performed. In connection with the 50th anniversary of the premiere of "A Life for
the Tsar" in 1886, attention is focused on the educational article "Musical Jubilee" by the Tomsk figure
G. S. Tomashinsky. Two reviews of the Irkutsk critic "Incognito" on productions of the opera "Ruslan
and Lyudmila" in 1900 are analyzed.
As a conclusion, the article notes that the appearance of Glinka’s operas in the musical life of
Siberian centers began with the amateur performance of fragments from "A Life for the Tsar", while
productions of integral performances by professional opera companies have been recorded in the
press since the mid-1890s. This is the first time that a similar perspective of the study of the performing
fate of Glinka’s operas in Siberia has been proposed
Plataforma Educativa Classroom en la enseñanza de Ciencias Sociales en Primer Año de Bachillerato durante el periodo lectivo 2023-2024
Authors: Monteros Guzmán Silvia Corina , Lara Pico Alejandra Betzabe , Jiménez Girón Doris Edilma , Charro Segovia Nuvia Yesenia , Zambrano Quijije Luis Fernando , Reinosa Rey Janeth del Carmen
Published: January 2025

Este estudio analiza el impacto de la plataforma educativa Classroom en la enseñanza de Ciencias Sociales en el primer año de bachillerato, empleando un enfoque constructivista y un diseño de investigación-acción. El paradigma constructivista facilitó la construcción de conocimientos sobre la problemática investigada, fomentando el interés investigativo. La investigación se desarrolló con un enfoque mixto (cuali-cuantitativo), recolectando datos a través de preguntas de investigación, encuestas y entrevistas. Se realizó una investigación básica que generó teorías para sustentar la información obtenida, lo que permitió interpretar los fenómenos observados y responder a las preguntas planteadas. El estudio tiene un alcance exploratorio-descriptivo y proporciona un análisis detallado de la influencia de Classroom en el proceso de enseñanza-aprendizaje de las Ciencias Sociales. Para la recolección de datos, se utilizó la técnica de entrevista con un guion dirigido a tres docentes de primer año de bachillerato, lo que permitió profundizar en sus perspectivas y aportar mayor relevancia a la investigación. Además, se aplicó una encuesta a 24 estudiantes del mismo nivel para evaluar la efectividad de Classroom en la enseñanza de esta materia.
Cuidados perdidos de enfermería relacionados con la perspectiva de la atención en pacientes de un hospital de segundo nivel
Authors: Arriaga Trejo Dulce Celeste , Pérez Guerrero Ruth Esperanza , Valenzuela Gandarilla Josefina
Published: January 2025

Los cuidados perdidos u omitidos son actividades de atención por los profesionales de enfermería, que deberían de realizarse, pero que no se ejecutan o se posponen por diversos factores, con repercusiones para el paciente. Analizar la relación entre los cuidados perdidos de enfermería y la perspectiva de atención en pacientes de un hospital de segundo nivel. Enfoque cuantitativo, diseño correlacional, prospectivo, transversal. En 95 enfermeras y 150 pacientes hospitalizados, se recurrió al instrumento MISSCARE del cuidado perdido de enfermería. En el análisis se utilizó el programa SPSS v27, se utilizó estadística descriptiva, frecuencias (), porcentajes (%), media, DE. Resultados: se identificó 3.2% de cuidado perdido por enfermería, la dimensión de cuidado básico 23.2%; factores condicionantes recurso humano 95.8% y recurso material 92.6%. Desde la perspectiva del paciente 34.2% percibió la pérdida de cuidados de enfermería, las dimensiones de mayor impacto el cuidado básico 59.3% y planificación del alta y educación 51.3%. Se encontraron correlaciones negativas en evaluaciones continuas de enfermería con el cuidado básico (rs=-.258; p0.012) y con el cuidado perdido del paciente (rs= -.293; p.004). Un bajo porcentaje de enfermería percibe la omisión del cuidado comparado con la perspectiva del paciente, el cuidado básico presentó mayor omisión, el factor de mayor influencia el recurso humano. El cuidado perdido de enfermería es percibido por los pacientes hospitalizados.
How Short-Term Rentals Impact Summit County, Colorado, Spatially and Economically: A GIS Analysis
Authors:   , Gilhooley Hanna
Published: January 2025

Summit County, Colorado, is experiencing a housing crisis influenced by the rise of short-term rentals (STRs). This project investigates how STRs spatially and economically impact the county. STRs are regarded as a reason for the housing crisis as they take away long-term housing from locals and increase housing market prices. Locals are forced to look for housing in neighboring counties such as Clear Creek, Eagle, Grand, Lake, and Park. Geographic Information Systems (GIS) can be used to analyze the spatial and economic impact of STRs in Summit County. Total population, median household income and STR locations are analyzed in ArcGIS Pro. The goal is to highlight the impacts of STRs on local housing affordability, potentially encouraging stricter regulations including charging tourism or business tariffs or giving incentives for short-term renters to long-term rent instead.
Desarrollo del Test de Efectos de las Redes Sociales (TERS)
Authors: Letelier Bruna , Serrate Keidy , Mendoza Guillermo
Published: January 2025

El constante crecimiento de la cantidad de usuarios y las horas de uso de las redes sociales ha despertado mucho interés de investigación. Sin embargo, los instrumentos disponibles para realizar la misma están enfocados principalmente en el diagnóstico de la adicción al uso de redes sociales. El objetivo principal del presente artículo es la presentación de una escala de uso de redes sociales y su efecto en la vida cotidiana, tomando en consideración los usos y efectos de las redes sociales en relación a la autoimagen y presión social, interferencia en la vida cotidiana y la dependencia. En el estudio participaron 205 estudiantes de la Universidad Privada de Santa Cruz de la Sierra (UPSA), con edades entre los 18 y los 25 años, y de ambos sexos (138 mujeres y 67 hombres). El test de Efectos de las Redes Sociales (TERS) es una prueba dirigida a ser una herramienta de identificación del uso otorgado a las RS y los efectos del mismo, para tomar medidas adecuadas, como la regulación y orientación hacia un uso positivo y, por consiguiente, hacia efectos positivos también. En base a los resultados obtenidos, se encontró que la fiabilidad y validez de la prueba es adecuada para la posterior aplicación a estudiantes universitarios.
Prion Diseases in Animals
Authors: Eduardo Salcedo
Published: January 2025

Prion diseases refer to a group of invariably neurodegenerative diseases in humans and animals, collectively known as transmissible spongiform encephalopathies (TSEs). These diseases are caused by proteinaceous infectious particles that lack nucleic acid, called prions. This paper reviews prion diseases occurring in animals, excluding human spongiform encephalopathies.
Prions in animals include scrapie or ovine spongiform encephalopathy, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), chronic wasting disease (CWD) of mule deer and elk, and feline spongiform encephalopathy (FSE). These diseases share several characteristics: a long incubation period (ranging from months to years or even decades), a clinical course lasting from weeks to years that invariably ends in death, lesions largely restricted to the central nervous system, and a lack of immune response. Histopathological changes include neuronal degeneration with vacuolation (spongiform degeneration), reactive astrocytosis, and often "amyloid plaque" formation. Variations exist among these diseases concerning incidence, breed and species susceptibility, and incubation time.
While extensive information is available for scrapie and BSE, data on other animal spongiform encephalopathies remain limited. This paper discusses the occurrence, host range, clinical signs, histopathology, transmission, and diagnosis of these diseases, with a particular focus on scrapie and BSE. It is suggested that BSE resulted from cattle ingesting meat and bone meal from scrapie-infected sheep, and TME is considered to have originated similarly. Bovine-to-bovine transmission has been linked to feeding cattle with bovine-derived meat and bone meal. Consequently, the ban on using ruminant-derived meat and bone meal has significantly reduced the incidence of BSE.
There is no direct evidence that animal spongiform encephalopathies are transmissible to humans. However, cases of a new variant of Creutzfeldt-Jakob Disease (vCJD) in teenagers and young adults in Britain and France revealed distinct neurological lesions not observed in classical CJD cases in adults from the United States, Australia, or Japan. These lesions, characterized by numerous amyloid plaques, are similar to those found in macaques inoculated with bovine prions.
None of the transmissible spongiform encephalopathies discussed in this paper have been reported in the Philippines
Aceptabilidad de un yogurt griego probiótico con jalea de mashua amarilla (Tropaeolum tuberosum) y maracuyá (Passiflora edulis flavicarpa)
Authors: Cruzado Meza Angela Brigit , Ccorahua Sequeiros María Rosa
Published: January 2025

El presente trabajo titulado Aceptabilidad de Yogurt Griego Probiótico con Jalea de Mashua Amarilla y Maracuyá tuvo como objetivo principal evaluar la aceptabilidad organoléptica del producto, analizando características como sabor, textura y apariencia, en diferentes concentraciones de mashua y maracuyá en la jalea (M1: 70% mashua y 30% maracuyá; M2: 60% mashua y 40% maracuyá). Para ello, se realizaron pruebas sensoriales con un grupo de 30 panelistas no entrenados, quienes evaluaron el producto mediante la escala hedónica con puntuaciones del 1 al 5. Los resultados indicaron que el yogurt con jalea que contenía 70% mashua y 30% maracuyá fue el más aceptado, destacándose por su sabor equilibrado, textura cremosa y color atractivo. Los panelistas calificaron positivamente su aroma, sabor ligeramente ácido y dulce, y su consistencia homogénea. Este estudio resalta el potencial de la combinación de ingredientes nativos y autóctonos de la región, los cuales ofrecen una opción saludable y atractiva para los consumidores, con un alto valor en la industria alimentaria.
The Role of Human Resources in Improving the Company's Financial Performance
Authors: Syukri Andi , Malik Tajuddin , Sandra Kurniawati , Mattalatta Mattalatta , Ansar Ansar , Farida Umi
Published: January 2025

This study examines the relationship between strategic human resource (HR) practices and financial performance, focusing on optimizing HR investments for sustainable economic success. The research addresses HR practices such as training, competency development, and reward systems in enhancing organizational outcomes. A systematic literature review (SLR) methodology synthesized findings from recent industry studies. This approach allowed for an integrative analysis of theoretical frameworks, including the Resource-Based View (RBV) and Agency Theory, to contextualize the impact of strategic HR practices on financial performance. The study highlights the significant influence of HR practices on organizational productivity, operational efficiency, and cost reduction. Practices like Green Human Resource Management (GHRM) enhance sustainability and improve reputation and financial outcomes. Integrating technology, such as data analytics and performance tracking systems, was identified as a crucial enabler for decision-making and resource optimization. The findings also emphasize aligning HR planning with organizational strategies to ensure coherent and effective workforce management. This research contributes to academic literature and practical applications by offering actionable strategies for optimizing HR investments. It provides a roadmap for managers to implement innovative HR practices that align with business objectives, foster sustainability, and enhance competitiveness. This study's limitations, including its reliance on secondary data, suggest avenues for future empirical research to validate and expand on these findings.
Plant-based diets and bone health
Authors: Migliaccio Silvia , Piciocchi Claudia , Defeudis Giuseppe , Mocini Edoardo
Published: January 2025

ABSTRACT The vegetarian tradition has very ancient origins. This type of nutritional pattern first “appeared” in the countries of the Far East. Switching from the typical modern Western diet to a vegetarian diet offers benefits, but this does not necessarily mean that such a diet can be considered “ideal” for all aspects of individual health. Thus, while a vegetarian/vegan diet plays a significant role in optimizing several specific issues related to metabolic and chronic disorders, there are controversial data regarding its potential risks to bone tissue. Thus, this review examines the potential issues associated with this type of nutritional pattern and bone health. KEYWORDS Skeleton, vegetarian, vegan, protein, minerals.
Correlation between gut microbiota and musculoskeletal diseases
Authors: de Sire Alessandro , Marotta Nicola , Zito Roberta , Invernizzi Marco , Ammendolia Antonio
Published: January 2025

Dysbiosis of the microbiota is linked to an increase in intestinal permeability and a simultaneous reduction in antioxidant functions, contributing to the creation of a chronic inflammatory state that results in weakening and fragility of the musculoskeletal system. Dysbiosis can, in fact, negatively influence the immune system, leading to an increase in the production of pro-inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), which can damage joint tissue. In this regard, the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) recently stated that several risk factors for osteoarthritis (OA) can interact with the intestinal microbiota, which appears to be a critical determinant of metabolism and bioavailability of OA drugs. Recent scientific evidence shows that changes in the composition of the microbiota, altering intestinal permeability and thus allowing leakage of bacteria and their components into the bloodstream, can trigger a systemic inflammatory reaction capable of contributing to the progression of joint degeneration. It is known that physical exercise can play a key role not only in improving the functioning of patients suffering from OA, but also in terms of modulating the composition of the microbiota, strengthening the immunity of the intestinal mucosa; furthermore, obesity, which is an important risk factor for the development of OA, has been linked to both dysbiosis of the gut microbiota and chronic inflammation, suggesting that complex connections exist between microbiota, obesity, and musculoskeletal pathologies. Intestinal dysbiosis can have a negative impact on bone health by influencing the RANK/RANKL/OPG pathway; in this context, it has been hypothesized that food supplements, prebiotics and probiotics can support an adequate balance of the intestinal microbiota and consequently bone health. In conclusion, the correlation between gut dysbiosis and musculoskeletal diseases, such as OA, sarcopenia, and osteoporosis, is still the subject of research and further studies are necessary to fully understand the underlying mechanisms. KEY WORDS: Microbiota, musculoskeletal diseases, gut, osteosarcopenia.
Associations of Individual and Neighborhood Factors with Disparities in COVID-19 Incidence and Outcomes
Authors: Samuels-Kalow Margaret E. , Cash Rebecca E. , Zachrison Kori S. , Rodney Fassinou Auriole Corel , Harris II Norman , Camargo Carlos A.
Published: January 2025

Introduction: The disproportionate impact of coronavirus 2019 (COVID-19) on Black and Hispanic communities has been widely reported. Many studies have used neighborhood racial/ethnic composition to study such disparities, but less is known about the interplay between individual race/ethnicity and neighborhood racial composition. Therefore, our goal in this study was to assess the relative contributions of individual and neighborhood risk to disparities in COVID-19 incidence and outcomes. Methods: We performed a cross-sectional study of patients with emergency department (ED) and inpatient visits to an academic health system (12 hospitals; February 1–July 15, 2020). The primary independent variable was race/ethnicity; covariates included individual age, sex, comorbidity, insurance and neighborhood density, poverty, racial/ethnic composition, education and occupation. The primary outcome was severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity; secondary outcomes included admission and death after COVID-19. We used generalized estimating equations to assess whether race/ethnicity remained signiﬁcantly associated with COVID-19 after adjustment for individual and neighborhood factors. Results: There were 144,982 patients; 5,633 (4%) were SARS-CoV-2 positive. Of those, 2,961 (53%) were admitted and 601(11%) died. Diagnosis of COVID-19, admission, and death were more common among non-Hispanic Black, Hispanic, Spanish-speaking patients, and those with public insurance. In the base model (adjusting for race/ethnicity, age, sex, and comorbidities), race/ethnicity was strongly associated with COVID-19 (non-Hispanic Black odds ratio [OR] 4.64 [95% conﬁdence interval (CI) 4.18–5.14], and Hispanic OR 6.99 [CI 6.21–7.86]), which was slightly attenuated but remained signiﬁcant after adjustment for neighborhood factors. Among patients with COVID-19, there was no signiﬁcant association between race/ethnicity and hospital admission, other than for patients with unknown race. Conclusion: This data demonstrates a persistent association between race/ethnicity and COVID-19 incidence, with Black and Hispanic patients at signiﬁcantly higher risk, which was not explained by measured individual or neighborhood factors. This suggests that using existing neighborhood factors in studies examining health equity may be insufﬁcient, and more work is needed to quantify and address structural factors and social determinants of health to improve equity.
Deletion of the Long Non-coding RNA ANRIL In Addition to the Protein-Coding Genes of the INK4-ARF Locus in the A549 Cell Line: An Existing Phenomenon or a Novel Genetic Alteration?
Authors: Sherifi Erfan , Fathi Fardin , Khadem Erfan Mohammad Bagher , Soleimani Farzad , Rahimi Karim , Zamani Fatemeh , Vahabzadeh Zakaria
Published: January 2025

Background: A549, a human lung adenocarcinoma cell line, is a KRAS mutant cell used for over 5 decades as a type II alveolar cell and non-small cell lung adenocarcinoma model. Cyclin-dependent kinase inhibitor 2 A (CDKN2A) and cyclin-dependent kinase inhibitor 2 B (CDKN2B) are protein-coding genes in the INK4-ARF locus and function as tumor suppressors and negative regulators of the cell cycle. These genes have been reported to be deleted in the A549 cell line. The Long non-coding RNAANRIL is located in the antisense direction of CDKN2B and shares a bidirectional promoter with CDKN2A. ANRIL is a negative regulator of the INK4-ARF locus genes and has an oncogenic role in cancers. ANRIL deletion in the A549 cell line has not been reported to date. Objectives: Herein, the presence of ANRIL was investigated in the A549 cell line. Methods: In this study, the A549 cell line from 2 different sources was tested for the presence of the INK4-ARF locus genes by polymerase chain reaction (PCR) using specific primers at both DNA and RNA levels. We compared our findings with Calu-6, MRC-5, and HepG2 cell lines. Results: Our analysis revealed that all protein-coding genes in the INK4-ARF locus, including CDKN2A and CDKN2B, were deleted in the A549 cell lines. Furthermore, we observed that ANRIL was entirely deleted in the A549 cells. The evaluated locus and all of its genes are present and expressed in other investigated cell lines. Conclusions: For the deletion of ANRIL in the A549 cell line, 2 scenarios are possible: First, from a structural point of view, the deletion of the protein-coding genes in the antisense of ANRIL in the INK4-ARF locus implies the possibility of a concurrent loss of ANRIL with the deletion of these genes in the A549 cell line. Second, as cancer cell lines are genetically unstable and are always susceptible to the acquisition of new mutations, ANRIL loss may have occurred later, following a novel genetic alteRNAtion in a population derived from a mutated cell.
Seroepidemiological Study of Human Herpes Viruses (EBV, CMV, VZV, HSV-1&2) Among Age Groups in Ahvaz, Iran Between 2011 - 2023
Authors: Haghi Navand Azadeh , Nazari Harmooshi Narges , Fakheri Sueini Venus , Jalilian Shahram , Matourian Elham , Alborzi Amir Mohammad
Published: January 2025

Background: Herpesviruses are widespread pathogens worldwide, often establishing lifelong infections in humans. However, seroprevalence data remain scarce for certain populations. To address this gap, a study was conducted to estimate the seroprevalence of human herpesviruses, including Epstein-Barr virus (EBV), Cytomegalovirus (CMV), Varicella zoster virus (VZV), and Herpes simplex virus types 1 and 2 (HSV-1&2), among different age groups in Ahvaz, Iran. Despite previous reports, detailed data on multiple herpesvirus infections are lacking in this region. Objectives: This study aimed to investigate the 11-year prevalence of human herpesviruses (EBV, CMV, VZV, HSV-1&2) among various age groups. Methods: A cross-sectional descriptive-analytical study was conducted on 14,126 serum samples from individuals aged 1 to 88 years. ELISA methods were used to test for the presence of the viruses. Results: The seroprevalence varied significantly by age and gender. The highest seroprevalence was observed for CMV (IgG) at 29.2%, while the lowest was for HSV-1&2 (IgM) at 0.8%. The highest seroprevalence was recorded in the 31 - 40 age group, whereas the lowest was in the 11 - 20 age group. Gender analysis revealed that seropositivity was higher in females (56.3%) compared to males (43.7%), with CMV IgG being the most common seropositive marker in both sexes. Conclusions: These findings underscore the potential for implementing targeted screening and vaccination programs for specific high-risk age groups. The data provide valuable epidemiological insights into the transmission of herpesviruses in southwestern Iran, emphasizing the need for enhanced prevention measures and further research into herpesvirus-related diseases.
النظم الانتخابية ودورها في توزيع المقاعد: دراسة تحليلية
Authors: لونا عبد الكريم داود
Published: January 2025

يتناول هذا البحث تحليلًا معمقًا للنظم الانتخابية وآليات توزيع المقاعد، مستعرضًا تأثيرها في تحقيق العدالة التمثيلية واستقرار الأنظمة الديمقراطية. يركز البحث على تعريف النظم الانتخابية باعتبارها الأطر القانونية والمؤسسية التي تنظم عملية اختيار الممثلين، مع بيان دورها في تحديد التوجهات السياسية وبناء التوازنات داخل المؤسسات التشريعية.
يتضمن البحث مناقشة شاملة لأنواع النظم الانتخابية، مثل نظام التمثيل النسبي ونظام الأغلبية، مع تحليل آليات تحويل أصوات الناخبين إلى مقاعد برلمانية. كما يتطرق إلى الأساليب المختلفة لتوزيع المقاعد، مثل القاسم الانتخابي المتغير والثابت، مع إبراز التأثيرات التي تتركها هذه الآليات على نتائج الانتخابات ومدى تحقيقها للعدالة في تمثيل مختلف القوى السياسية والاجتماعية.
يُسلط البحث الضوء على التحديات التي تواجه النظم الانتخابية، بما في ذلك تعقيدات توزيع المقاعد وأثرها على الاستقرار السياسي. كما يقدم دراسة نقدية لمدى تحقيق هذه النظم للأهداف الديمقراطية من خلال تحقيق التوازن بين عدالة التمثيل وفعالية الحكم، مما يعكس الأهمية المتزايدة لدراسة النظم الانتخابية في ظل التغيرات السياسية المتسارعة.
Drugs for Irritable Bowel Syndrome
Authors:   Editors from The Medical Letter
Published: January 2025

Irritable bowel syndrome (IBS) is a common disorder characterized by recurrent abdominal pain and altered bowel habits, often accompanied by bloating.1-4 IBS is classified by its predominant bowel symptom: constipation (IBS-C), diarrhea (IBS-D), mixed type (IBS-M), or unclassified (IBS-U).1 Since the exact cause of IBS is unknown, the goal of treatment is symptom control.
Safety of Drugs for IBS in Pregnancy and Lactation
Authors:   Editors from The Medical Letter
Published: January 2025

Safety of Drugs for IBS in Pregnancy and Lactation
Environmental factors distress housing development in nigeria and other regions of the world
Authors:   Department of Architecture, Ladoke Akintola University of Technology, Ogbomosho, Nigeria, Olusola Oladapo Makinde , Odunola Olayinka Onigbogi ,   Department of Architecture, Ladoke Akintola University of Technology, Ogbomosho, Nigeria, Olubukunmi Temitope Makinde ,   Department of Estate Management, Osun State University, Osogbo, Nigeria, Olabode Oludayo Akangbe ,   Department of Architecture, Ladoke Akintola University of Technology, Ogbomosho, Nigeria
Published: January 2025

A clean and healthy environment forms a crucial aspect of our daily living, which becomes a vital factor for a healthy lifestyle. Global warming, flood, deforestation, overexploitation of natural resources, climate change, pollution, among others are some of the environmental challenges that most nation is facing. This study aims to increase the consciousness of environmental factors distress housing development. The methodology used involved the analysis and review of previous related literature in reverence to the issue in Nigeria and other regions of the world with a view to develop a guide for housing development. The study looked at environmental factors in housing using Nigeria and other regions of the world as a case study. This study carried out a general overview of environmental factors in housing, environmental issues, and challenges in this area. The study used secondary sources of data from relevant literature to obtained information related to these objectives. The study also looked at the control measures to alleviate the impacts of environmental factors on housing in each continent and the way forward in building a sustainable environment. The results from the finding shows that promoting effective clean housing production, reduction of noise, water and air pollution, and reduction of solid waste, will alleviate environmental issues in cities around the globe. Also, effectively improving the environmental consciousness of people will significantly reduce environmental factors distress housing development in Nigeria and other regions of the world. The study recommended and concluded that there is a need to focus on designing eco-friendly buildings, sustainable building operations, and limiting the negative impacts of housing on the environment, such as noise, air, and water reduction and focusing on nature conservation.
الألفاظ الأعجمية في القرآن الكريم: دراسة تاريخية معجمية [Foreign Words in The Holy Qur’an: A Historical Lexical Study]
Authors: al-Karīm az-Zubaydī ʽAbd
Published: January 2025

The article examines the words of non-Arabic origin in the Qur’an and their appearances in Arabic dictionaries.
جهود المعاصرين في خدمة لسان العرب وفهرسته [Contemporary Efforts Concerning the Lisān al-ʿarab and Its Indexing
Authors: Ḥaddād Ḥannā
Published: January 2025

The article provides an analysis of Ibn Manẓūr’s comprehensive Arabic dictionary, entitled Lisān al-ʿarab, assessing the contemporary endeavours to provide indices to this voluminous work.
Status, Hukum,Peraturan, ,Pemerintah, ,Pengganti, Undang-Undang,Nomor, 2 Tahun, 2022, Tentang Cipta,Kerja Dalam Ketatanegaraan,Indonesia
Authors: Agung Saputra
Published: January 2025

Government Regulation in Lieu of Law (PERPPU) Number 2 of 2022 concerning Job Creation is the Indonesian government's response to facing a pressing emergency situation. This research aims to analyze whether the Perppu meets the criteria regarding the need for urgency in accordance with the principles of Indonesian constitutional law. Apart from that, this research will also examine the legal status of the Perppu in the Indonesian constitutional system. By using a normative juridical approach, this research found that Perppu Number 2 of 2022 was issued to deal with various urgent economic and investment problems, as well as to create a more conducive business climate in the midst of the pandemic. However, there is still debate regarding the validity and urgency of issuing this Perppu, as well as its impact on existing legal provisions. It is hoped that these findings will provide a deeper understanding of the legislative process and the establishment of Perppu in Indonesia, as well as the implications for law enforcement and government governance