bluuebunny/crossref_metadata_2025 huggingface dataset:
PEMODELAN POTENSI EROSI DAN SEDIMENTASI HULU DANAU LIMBOTO DENGAN WATEM/SEDEM
Authors: Alfianto Ardian , Cecilia Shandy
Published: December 2020

Erosion and sedimentation caused 4,000-hectare siltation in Limboto. Experts predicted that Limboto will be extinct in 2031. Revitalization program ‘Limboto Lake Revitalization’ has been carried out since 2017, with sabo technology as the action carried out to restrain sedimentation rate and to save the lake from extinction. This study aims to measure erosion and sedimentation potential in upstream of Limboto including 12 rivers (sub-DAS), using WaTEM/SEDEM model Two outputs resulted through this study are total sedimentation potential and identification of sedimentation zoning on each river. Based on soil type and other triggering factors, 5 of 20 rivers have the biggest sedimentation potential to deliver to Limboto, namely Batulayar 193.662 m3, Biyonga Baluta 123.095 m3, Alo1 120.273 m3, Alo 115.204 m3 and Molamahu 73.058 m3. The model was visually calibrated by considering the rivers’ sedimentation volume collected by JICA and BWS Sulawesi II. The result shows different score depending on the soil type, slope, land cover and other parameters. Sabo dam has to be reviewed regularly and on-schedule, since its current data is not actual and upstream rivers have highly dynamic and fluctuative sediment as well.
PENILAIAN RISIKO KEAMANAN BENDUNGAN DI JAWA TIMUR
Authors: Pramudawati Maria Asunta Hana
Published: December 2020

Dam risk assessment is basically a additional to a standard-based approach, which is a conservative approach to dam engineering. For existing and new dams, dam risk assessment aims to determine whether existing hazard risks can be tolerated, and if hazard risks cannot be tolerated, actions to reduce risk are planned. Risk assessments for existing dams can also be used as a basis for determining priorities in carrying out the required repair or rehabilitation work. This paper discusses the dam risk assessment at Sengguruh Dam, Sutami Dam, Lahor Dam, Wlingi Dam, Bening Dam, Wonorejo Dam and Selorejo Dam. The methods used in risk assessment include the preparation of risk assessments, risk analysis, risk evaluation, risk reduction and management. These seven dams are managed by one manager, namely PJT I and are considered to be representative of this method that can be used to determine the priority value of dam handling. Based on the results of the assessment, the 7 dams fulfill the risk criteria. The next action that can be taken for these dams is to monitor the dam's behavior on a regular basis and in the aftermath of the earthquake, renew and socialize the RTD.
WAVE FORCE OF THE 1883 KRAKATAU TSUNAMI ON THEOUTER SEA DIKE IN JAKARTA BAY
Authors: Simanjuntak Eduardo Meyrianso , Ginting Juventus Welly Radianta , Putra Ida Ayu Irawati Diah Ratna
Published: December 2020

The increased volcanic activity of Mount Anak Krakatau has raised the awareness of the potential tsunami impact for the construction of National Capital Integrated Coastal Development (NCICD) Project. This research is aimed to evaluate the tsunami impact on the outer sea dike of NCICD. The 1883 Krakatau tsunami was used as reference to evaluate the coastal infrastructure. Time series data from the 1883 Krakatau tsunami is extracted as an input to calculate the wave force. There are three different methods used such as Rule of Thumb (wave force is twice that of hydrostatic force), Linear Theory, Sainflou method. The results show that the tsunami will hit the outer sea dike with at least force about 70 kN. The outer sea dike OSD-1A is the least impacted sea dike while OSD-3A is the most impacted. For OSD-1A, Rule of Thumb and Linear Theory estimate 303.30 kN of wave force while Sainflou method predicts only 73.45 kN. On the other hand, OSD-3A endured wave force of 131.91 kN (Sainflou method) or 531.91 kN (Rule of Thumb and Linear Theory). Sainflou method is for efficient design while the other methods have the benefit of safety factor
General aspects of xeroderma pigmentosum: A review
Authors: Moreira Danilo José Silva , Fonseca Juliana Brito da , Rossi Karoline , Vasconcelos Suzana dos Santos , Oliveira Vinicius Faustino Lima de , Dias Claudio Alberto Gellis de Mattos , Oliveira Euzébio de , Dendasck Carla Viana , Araújo Maria Helena Mendonça de , Brito Maysa Vasconcelos , Fecury Amanda Alves
Published: December 2020

Xeroderma Pigmentoso (XP) is a rare, recessive and autosomal genetic disease that also affects both sexes and all ethnicities, being closely associated with communities with a high rate of inbreeding. The aim of this review was to detail the main routes of DNA repair of XP, the different functional defects that result in the development of the 8 types of XP, the main characteristics of the clinical picture of a patient with XP, the main comorbidities associated with XP, and the treatments available or that are still in studies for individuals affected by XP. The bibliographic research was carried out in the databases: Redalyc, Institutional Repository of the Federal University of Juiz de Fora, Scielo, Brazilian Digital Library of Theses and Dissertations, Science Research.com, Lilacs and Pub Med, using keywords or their associations: Xeroderma – Xeroderma Pigmentoso. XP is a genetic disease that has no cure; the individual with XP has a photosensitive skin and, when exposed to UV radiation, may develop several dermatological complications; the manifestations of XP are directly linked to the genetic defect; NER is undoubtedly the main route of DNA repair when it comes to XP; in XP-V the by-pass of the tape with the DNA lesion is not done by polymerase pol eta but by another polymerase of the Family Y; defects in DNA repair pathways can cause not only XP, but also other diseases; and the treatment for XP is palliative. It consists of the use of specific UV protectors, drugs, repair enzymes and adenoviral vectors, as well as cryosurgery, photodynamic therapy (PDT), surgical removal of tumors and psychological follow-up.
Análisis tecnológico del material de Areal Morro Branco, Porto Grande, Amapá, por fraccionamiento
Authors: Almeida Hellen Karine Santos , Paiva Matheus Monteiro Ybanez , Dias Claudio Alberto Gellis de Mattos , Fecury Amanda Alves , Dendasck Carla Viana , Dantas Antônio de Pádua Arlindo
Published: December 2020

La arena natural se extrae utilizando métodos de minería, incluso para la fabricación de arenas artificiales. La arena es ampliamente utilizada en varias áreas. Como agregados de construcción; industrias de procesamiento de materiales; tratamiento de agua y alcantarillado. El Areal de la empresa Morro Branco, donde se recogieron las muestras de arena, se encuentra alrededor de la sede del municipio de Porto Grande. El municipio de Porto Grande en Amapá se encuentra en el centro del estado a 108 kilómetros de la capital Macapá. El objetivo de esta investigación fue realizar el análisis tecnológico del material de Areal Morro Branco, Porto Grande, Amapá, por fraccionamiento. La arena fue retirada de un arenal en el municipio de Porto Grande – AP con el uso de herramientas manuales para la recolección. 03 (tres) se recogieron muestras de diferentes puntos con diferente composición, debido a la existencia de materia orgánica en su composición. Para la descomposición de la materia orgánica de la muestra se utilizó silicato de sodio con una concentración del 10% y bromoformo. Estos procedimientos se determinaron en la muestra seca en un horno durante 24 horas aproximadamente a 110oC, y el porcentaje de humedad (%U), esto, también se determinó en la muestra original. Se verificó a través de las pruebas y procedimientos realizados que la humedad de la arena del Areal Morro Branco está influenciada por la materia orgánica resultante de las zonas forestales y los recursos hídricos del entorno del Areal. La granulometría de los puntos de los que se recogió la arena en la arena tiene características de grano en ángulo y sub-ángulo. Con la ayuda de la densidad de bromoforma, era factible darse cuenta de que la arena de la que se recogió la muestra tiene agregados de cuarzo, feldespato con una densidad inferior a 2,89 g/cm3. Se ha sugerido que la arena también puede tener derivados minerales de arena con una densidad superior a 2,89g/cm3, que son Olivino y Piroxeno.
Общие аспекты пигментной ксеродермии: обзор
Authors: Moreira Danilo José Silva , Fonseca Juliana Brito da , Rossi Karoline , Vasconcelos Suzana dos Santos , Oliveira Vinicius Faustino Lima de , Dias Claudio Alberto Gellis de Mattos , Oliveira Euzébio de , Dendasck Carla Viana , Araújo Maria Helena Mendonça de , Brito Maysa Vasconcelos , Fecury Amanda Alves
Published: December 2020

Xeroderma Pigmentoso (XP) является редким, рецессивным и аутосомно-генетическим заболеванием, которое также поражает как пол, так и все этнические группы, тесно связанные с общинами с высоким уровнем инбридинга. Целью данного обзора было подробно основные маршруты восстановления ДНК XP, различные функциональные дефекты, которые приводят к развитию 8 типов XP, основные характеристики клинической картины пациента с XP, основные сопутствующие заболевания, связанные с XP, и методы лечения доступны или которые все еще находятся в исследованиях для лиц, пострадавших от XP. Библиографические исследования проводились в базах данных: Redalyc, Институциональное хранилище Федерального университета Juiz de Fora, Scielo, Бразильская цифровая библиотека диссертаций и диссертаций, Science Research.com, Lilacs и Pub Med, используя ключевые слова или их ассоциации: Xeroderma – Xeroderma Pigmentoso. XP является генетическим заболеванием, которое не имеет лечения; человек с XP имеет светочувствительную кожу и, при воздействии УФ-излучения, может развиться несколько дерматологических осложнений; проявления XP напрямую связаны с генетическим дефектом; NER, несомненно, является основным маршрутом восстановления ДНК, когда дело доходит до XP; в XP-V облет ленты с поражением ДНК делается не полимеразой pol eta, а другой полимеразой семьи Y; дефекты в путях восстановления ДНК могут вызвать не только XP, но и другие заболевания; и лечение XP является паллиативным. Он состоит из применения специфических УФ-протекторов, препаратов, ремонтных ферментов и аденовирусных переносчиков, а также криохирургии, фотодинамической терапии (PDT), хирургического удаления опухолей и психологического сопровождения.
Effect of Temperature on the Properties of the Rolled Composites Based on Polyethylene and Rubber Particles
Authors:   Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, Moscow, 119991 Russia, Serenko O. A. , Efimov A. V. ,   Chemistry Department, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991 Russia
Published: December 2020

The stress–strain properties of the isotropic and rolled composites based on polyethylene (PE) and rubber particles are studied. The mechanical properties are determined at 20, 50, and 70 °С. It is shown that one of the factors ensuring the maintenance of plasticity of the filled rolled PE is an increase in the crack resistance of the matrix, which is manifested in the changes of the forms of defects that arise during tension. At the rubber content no more than 20 wt %, a temperature rise leads to a change in the mechanism of the composite fracture from brittle to ductile. It is shown that the positive effect of rolling of the rubber plastics is retained during their testing at elevated temperatures.
CODE MIXING ANALYSIS OF INDONESIAN INFLUENCERS ON INSTAGRAM
Authors: Fazriani Riza
Published: December 2020

This research is about code mixing used by Indonesian Influencers on Instagram. This researchaims to find out the types of code mixing used by Indonesian Influencers on Instagram. Thisresearch focuses on types of code mixing used by Indonesian Influncers by Musyken (2000) theory.The data then were analyzed using qualitative method. The research used observation anddocumentation to find out the data. The finding showed that there were 25 data of code mixingfrom 5 Indonesian Influencers and the research used 5 data to analyzed. The research concludedthat there are three types of code mixing used by Indonesian Influencers. They are insertion,alternation, and congruent lexicalization.
KONSEP POLITIK MELAYU DI PULAU BANGKA (STUDI ANALISIS UNDANG-UNDANG SINDANG MARDIKA)
Authors: Rohman Abdul
Published: December 2020

Penelitian ini bertujuan untuk mengangkat sejarah konsep politik Melayu berdasarkan hukum adat masyarakat etnis Melayu yang ada di Pulau Bangka. Dilihat dari berlakunya hukum adat di Pulau Bangka dipersatukan oleh kesatuan wilayah masyarakat hukum adat terestrial, yaitu hukum adat berdasarkan pertalian tempat tinggal yang kental sekali dengan etnis Melayu dalam kehidupan masyarakatnya. Konsep Politik etnis Melayu dalam bahasan ini akan lebih ditonjolkan mengenai kekuatan reputasi politik dalam mengatur wilayah Bangka serta menjaga kestabilan sosial, ekonomi dan politik pada masa itu. Metode yang digunakan dalam penelitian ini adalah kualitatif dokumentasi historis. Hasil penelitian ini akan dibahas mulai dari masa Kesultanan Palembang sebagai periode lahirnya struktur kekuasaan yang membentuk Undang Undang Sindang Mardika sehingga muncul kebijakan ekonomi politik, ekologi politik, sosial budaya dan politik Islam dalam eksistensinya. Di dalam konsep politik Melayu ini akan melihat perkembangan dari awal abad ke-18, sehingga dapat dibedakan perubahan yang terjadi dari masa pra kolonial hingga masa kini (kemerdekaan). Penelitian ini menggunakan teori rekonstruksi hukum menurut Lawrence M. Friedman berdasarkan pembangunan masyarakat Melayu menuju kedaulatan kearifan lokal, yaitu: substansi hukum, struktur hukum dan budaya hukum. Hal tersebut penting untuk meninjau kembali sebagai literasi dan direalisasikan.Kata kunci: Konsep, Politik Melayu, Rekonstruksi Politik hukum
Analysis of performance appraisal system with 360 degree feedback method in PT. PERTAMINA RU IV (PERSERO) Cilacap
Authors: Prasetyaningrum Dina , Setiawan Yudi Agus
Published: December 2020

The 360 degree feedback method is one of the performance appraisal methods which implementation takes an assessment of the parties around the employee being assessed. The 360 degree feedback method performance appraisal system conducted at PT. Pertamina RU IV (Persero) Cilacap aims to determine the implementation of the performance appraisal system using the 360 degree feedback method, determine employee performance with what variables are used in performance appraisal, and obtain performance optimization. The research method used in this research uses qualitative methods with a quantitative approach. The 360 degree feedback method is used to find data from respondents, namely from superiors, colleagues, themselves and subordinates. Based on the research that had been done, it had succeeded in determining the best workers from each discipline and position based on the calculation of variables and indicators used. The 360 degree feedback performance assessment can help the company appropriately to provide rewards for workers with the highest percentage and provide punishment for workers with lowest percentage. The calculation of these variables and indicators helps the company to find the right solution in an effort to optimize the performance of its employees.Keywords: performance, performance appraisal, 360 degree feedback method
Seasonal dynamics of the main primary production characteristics of phytoplankton and its microzooplankton grazing in the surface coastal waters of the Black sea
Authors:   Institute of Marine Biological Researches of RAS, Stelmakh L.V.
Published: December 2020

Seasonal variability of phytoplankton biomass, “pure” primary production and its share consumed micro¬zooplankton, as well as the specific microzooplankton grazing rate of phytoplankton for the surface layer (0-1 m) in coastal waters of the Black Sea was studied. Almost 80% of the total annual primary’ produc¬tion of phytoplankton is created by phytoplankton with the average cell volume .from 150 to 4000 mm3. The main share of annual primary production, eaten by microzooplankton (86%) is also associated with these algae sized groups.
Algoflora of Donuzlav gulf (expedition materials of HS “Donuzlav” in june 7-10, 2016)
Authors:   Institute of Natural and Technical Systems, Andreeva N.A. , Grebneva E.A. ,   Institute of Natural and Technical Systems
Published: December 2020

The preliminary investigation of cultivated cyanobacteria and microalgae in aqueous phytoplankton samples took place at seven complex oceanographic stations along the coast of western Crimea during the expedition of HS “Donuzlav”. The main phytoplanktonic representatives at the most of stations were cyanobacteria and diatoms. We isolated cyanobacteria (3) and diatom (2) strains from two samples.
Features of bat diversity monitoring in Sochi National Park
Authors:   Sochi State Natural National Park, Romashin A.V.
Published: December 2020

Features of monitoring of wing-handed animals in Sochi National Park by a combination of the acoustic route account with the universal accounting of troglofilian types in karst cavities are shown. Transition from linear recalculating coefficients to cubic is reasonable. The received results on number were included into new edition of the Red List Krasnodarskogo kraya.
Preliminary results of field observation and analysis of recreation load on the sea coastal zone (on the example of the beach “Vasileva balka”, Sevastopol)
Authors:   Institute of Natural and Technical Systems, Agarkova-Lyakh I.V. , Tamoikin I.Yu. ,   Institute of Natural and Technical Systems
Published: December 2020

The results of field observation for recreation load on Sevastopol beach “Vasileva balka” from May till October 2016 was presented. Maximal attendance of the be3ch was registered during July – mid-August. Median of guest number from 9 till 19 was 380, minimum – 130, maximum – 625 persons. Maximal and average actual recreation loads on the beach did not exceed values estimated by SanPiN norms.
Использование малоуглового измерителя дисперсности в автоматизированных системах непрерывного мониторинга гранулометрического состава аэрозолей
Authors:   Sevastopol branch State Oceanographic Institute, Dyakov N.N. , Malchenko Yu.A. ,   Sevastopol branch State Oceanographic Institute, Bobrova S.A. ,   Sevastopol branch State Oceanographic Institute, Ryabinin A.I. ,   Sevastopol branch State Oceanographic Institute, Lipchenko A.E. ,   Sevastopol branch State Oceanographic Institute, Taranov V.V. ,   Institute of Colloid Chemistry and Water Chemistry
Published: December 2020

We present the results of observations of the particle size distribution of aerosols on a stationary post in the city of Sevastopol in 2015-16 years. The basic patterns of aerosol distribution in individual size groups and their relationship with environmental parameters. The relevance of the proposed monitoring of the various indicators of aerosol was noted.
Monitoring of the geomagnetic field variations at the high- mountain biospheric station «Dzhuga» and forecasting of natural disasters and extreme weather
Authors:   Westem-Caucasus Research Center, Lukin A.N. , Rodimcev P.G. ,   University of Saint-Petersburg, Eskin N.B. ,   University of Saint-Petersburg
Published: December 2020

In the paper realization of the research project connected with monitoring of the Earth magnetic field variations at the high-mountain biosphere station «Dzuga» is considered. The acoustic channel of influence of the space weather and technologies of visualization of the geomagnetic and acoustic fields with use of high-sensitivity model experimental systems is considered. The new concept of forecasting of extreme natural events with use of the universal phenomenon of spacial self-synchronization of oscillations of geomagnetic and acoustic fields and on the basis of the analysis of the structure of holograms of physical fields is formulated.
Features of degradation faults modeling of initial measurers of monitoring systems
Authors:   Sevastopol State University, Skatkov A.V. , Voronin D.Y. ,   Sevastopol State University, Skatkov LA. ,   Sevastopol State University
Published: December 2020

The features of the modeling of degradation faults of the primary measurers of monitoring systems and networks based on their basis are considered. An integrated approach to modeling invited to perform on the basis of the use and development of analytical relations obtained for queuing systems. For this purpose it has been proposed a new functional logic component – degradator, which is the minimum structural unit of the simulation. The results of computational experiments for the purpose of estimating the degree of influence the degradation rate parameters on the system performance are given in the paper.
Low-frequency variability of the wind field, geostrophic velocities and ocean surface temperature in Сanary upwelling according to satellite data
Authors:   Institute of Natural and Technical Systems, Polonsky A. B. , Screbrennikov A.N. ,   Institute of Natural and Technical Systems
Published: December 2020

The effect of long-period variability of the speed and direction of sea surface winds, absolute geostrophic velocities on the sea surface temperature (SST) and thermal upwelling index (TUI) trends in the Canary upwelling region is considered using satellite data from 1980 to 2016. Despite the statistically significant intensification of the surface wind in the region, there were no long-term trends in the upwelling intensity (expressed in SST terms), as well as in the geostrophic velocities. It is concluded that the absence of a significant intensification of the Canary upwelling with the increase of the drift wind in the region is associated with a general weakening of the northeast trade wind due to the observed global warming.
The Analysis of Factors that Influencing Mother's Knowledge Level on Basic Immunization
Authors: Fadly Sul , Fitriani Rini , Asriani
Published: December 2020

Introduction: One of the goals of WHO formulated at the Atlanta meeting in 1978 was to achieve health for all by 2000. The purpose of this study is to describe the factors that influence the level of mother’s knowledge regarding basic immunization.

Methods: The research was conducted in January - February 2020 in the Dahlia Health Center in Makassar. The sample was 80 mothers whose babies were immunized at the Dahlia Health Center. A purposive sampling method was used. The data collection method used was a survey questionnaire that was distributed to respondents. The data analysis used was a univariate data analysis using the SPSS.

Results: The largest subjects were senior high school education and the smallest subjects were university education. Most of the subjects were housewives or unemployed (75%) and the least of the subjects were civil servants (3.75%). Most subjects in this study were aged 21-35 years old (53.75%) and the least subjects were under 20 years old (15%). All respondents were Muslim (100%). Most of the family environment factors that their family did not accompany them for immunization (53.75%) and community environmental factors that around people brought their children for immunization (100%).

Conclusion: All factors of this study affect the mother’s knowledge but we can conclude that the most role influence of factors to knowledge mother were environment and religion.
Analisis Antibodi Ireguler pada Reaksi Inkompatibel Darah Transfusi
Authors: Kartika Irna Diyana , Thamrin Hilma Yuniar , Muhiddin Rachmawati , Arif Mansyur , Samad Ibrahim Abdul
Published: December 2020

Latar belakang: Terjadi kasus inkompatibilitas karena pemberian darah yang inkompatibel dapat disebabkan oleh dua hal, yang pertama akibat ketidakcocokan golongan darah saat melakukan transfusi sehingga terjadi reaksi hemolisis intravaskular akut dan juga dapat disebabkan oleh reaksi imunitas antara antigen dan antibodi karena adanya golongan darah lain atau antibodi ireguler. Penelitian ini bertujuan untuk menganalisis antibodi ireguler pada hasil inkompatibilitas darah transfusi uji silang serasi darah transfusi.

Metode: Penelitian ini merupakan penelitian observasional dengan menggunakan metode cross sectional. Sampel penelitian sebanyak 70 sampel inkompatibel uji silang serasi yang ditemukan di Unit Bank Darah RSUP Dr. Wahidin Sudirohusodo Makassar dan Unit Donor Darah PMI Makassar. Dilakukan pemeriksaan golongan darah dan uji silang serasi jika sampel yang telah di lakukan uji silang serasi dan hasilnya terjadi reaksi inkompatibel golongan darah maka sampel tersebut  diambil kemudian di lanjutkan ke Direct antiglobulin test. Sampel yang Direct antiglobulin test positif dilanjutkan dengan pemeriksaan monospesifik yaitu tes IgG dan C3d. Analisis data menggunakan Metode analitik, yaitu dengan uji Chi Square untuk menilai variabel yang berhubungan dengan antibodi ireguler.

Hasil: Penelitian menunjukkan bahwa, dari 70 sampel yang mengalami reaksi inkompatibilitas ternyata hanya 7 sampel yang positif memiliki antibodi ireguler, di antaranya Anti E 3 (4,29%), anti CDEd 1 (1,42%), dari ketujuh sampel yang positif terdapat 2 (2,86%) sampel yang positif semua pada sebelas sel panel tersebut dan terdapat 1 (1,42%) sampel yang positif pada sel panel kecil (sel 1 dan sel 2) untuk skrining antibodi.

Kesimpulan: Kejadian inkompatibel golongan darah sebagian besar bukan karena adanya antibodi ireguler, hanya sekitar 10% inkompatibel akibat antibodi ireguler terjadi maka skrining antibodi ireguler belum menjadi urgensi di setiap Unit pelayanan Transfusi darah maupun di unit Bank darah Rumah sakit.
Amalan Terbaik Pelaksanaan Sertu dalam Industri Halal di Malaysia
Authors: Abd Aziz Sumaiyah , Mohd Salleh Mohd Mahyeddin , Ab Halim Mustafa ‘Afifi , Md Said Hasdhatul Nor Aliah
Published: December 2020

Pelaksanaan sertu menjadi semakin penting bagi industri sederhana dan besar di Malaysia yang ingin mendapatkan pensijilan halal. Walaupun sertu bukanlah sesuatu yang wajib dilakukan, syarikat perlu mewujudkan prosedur operasi standard (SOP) secara bertulis berkaitan sertu sebagai persediaan sekiranya berlaku ketidakakuran yang perlu kepada proses sertu (jika berkaitan) dan ini digariskan sebagai salah satu keperluan dalam Sistem Jaminan Halal (HAS), Sistem Pengurusan Halal Malaysia 2019. Artikel ini bertujuan untuk melihat amalan terbaik pelaksanaan sertu dalam industri halal di Malaysia. Kajian ini dilaksanakan secara kualitatif, dengan menumpukan kepada kaedah pengumpulan data secara analisis dokumen, temubual bersemuka dan pemerhatian secara langsung. Terdapat lapan dapatan yang diketengahkan dalam kajian ini iaitu keperluan garis panduan khusus bagi setiap skim halal; prosedur dan pengurusan sertu; peluang kerjaya sebagai jurusertu yang bertauliah; keperluan kepada penganjuran kursus/latihan sertu; cabaran yang dihadapi dalam melaksanakan proses sertu; fi pengurusan dan khidmat sertu; pangkalan data penyedia perkhidmatan sertu dan inovasi dalam menjalankan sertu. Kajian ini mencadangkan agar JAKIM dan JAIN/MAIN menambahbaik dan memantapkan garis panduan sertu yang sedia ada demi kebaikan industry halal di Malaysia.
Dynamics and Bifurcation of a Second Order Quadratic Rational Difference Equation
Authors: HERZALLAH Shahd , SALEH Mohammad
Published: December 2020

In this paper, we study the dynamics and bifurcation of $$ x_{n+1} = \frac{\alpha+ \beta {x^2}_{n-1}}{A+B {x_n}+C{x^2}_{n-1}}, \ n=0,\ 1, \ 2, \ ... $$ with positive parameters $\alpha,\ \beta, \ A, \ B, \ C, $ and non-negative initial conditions. Among others, we investigate local stability, invariant intervals, boundedness of the solutions, periodic solutions of prime period two and global stability of the positive fixed points.
Fitting an Epidemiological Model to Transmission Dynamics of COVID-19
Authors: TSEGA Endalew
Published: December 2020

A rapid increase in daily new cases was reported in the world from February 19 to April 3, 2020. In this study, a susceptible-infected-recovered-dead (SIRD) was developed to analyse the dynamics of the global spread of COVID-19 during the above-mentioned period of time. The values of the model parameters fitted the reported data were estimated by minimizing the sum of squared errors using the Levenberg-Marquardt optimization algorithm. A time-dependent infection rate was considered. The set of differential equations in the model was solved using the fourth order Runge-Kutta method. It was observed that a time-dependent parameter gives a better fit to a dynamic data. Based on the fitted model, the average value of basic reproduction number (\textit{R0}) for COVID-19 trasmission was estimated to be 2.8 which shows that the spread of COVID-19 disease in the world was growing exponentially. This may indicate that the control measures implemented worldwide could not decrease the COVID-19 transmission.
Boolean Hypercubes, Mersenne Numbers, and the Collatz Conjecture
Authors: CARBÓ DORCA Ramon
Published: December 2020

This study is based on the trivial transcription of the vertices of a Boolean \textit{N}-Dimensional Hypercube $\textbf{H}_{N} $ into a subset $\mathbb{S}_{N}$ of the decimal natural numbers $\mathbb{N}.$ Such straightforward mathematical manipulation permits to achieve a recursive construction of the whole set $\mathbb{N}.$ In this proposed scheme, the Mersenne numbers act as upper bounds of the iterative building of $\mathbb{S}_{N}$. The paper begins with a general description of the Collatz or $\left(3x+1\right)$ algorithm presented in the $\mathbb{S}_{N} \subset \mathbb{N}$ iterative environment. Application of a defined \textit{ad hoc} Collatz operator to the Boolean Hypercube recursive partition of $\mathbb{N}$, permits to find some hints of the behavior of natural numbers under the $\left(3x+1\right)$ algorithm, and finally to provide a scheme of the Collatz conjecture partial resolution by induction.
Polidocanol sclerotherapy for intraoral hemangioma of buccal mucosa: a rare case report
Authors: HANGE Venkatesh
Published: December 2020

The term hemangioma derives from the Greek word, “hema” which expresses blood, “angio” implies vessel,
“oma” corresponds to tumor. A hemangioma is a type of an innocuous lesion of blood vessels or vascular components defined by a proliferative growth stage and a very prolonged involutive stage. The prevalence of hemangiomas is estimated to be around 2-3% in neonates, 10-12% in the first year of life, and 22-30% found amongst babies whose weight is less than 1000g at the time of birth. Most of the hemangiomas occur as single lesion. Peripheral hemangiomas treated by surgical excision is an example of gold standard treatment for hemangiomas. Alternatively sclerosing solutions may be used as they obliterate blood vessels, thereby leading to fibrosis and disappearance of the hemangioma. It is relatively uncommon in the oral cavity. Polidocanol (aethoxysklerol) is a detergent solution which act by causing localized inflammatory reaction.
A genome-wide CRISPR screen identifies regulators of MAPK and MTOR pathways that mediate resistance to sorafenib in acute myeloid leukemia
Authors: Damnernsawad Alisa , Bottomly Daniel , Kurtz Stephen E. , Eide Christopher A. , McWeeney Shannon K. , Tyner Jeffrey W. , Nechiporuk Tamilla
Published: December 2020

Drug resistance impedes the long-term effect of targeted therapies in acute myeloid leukemia (AML), necessitating the identification of mechanisms underlying resistance. Approximately 25% of AML patients carry FLT3 mutations and develop post-treatment insensitivity to FLT3 inhibitors, including sorafenib. Using a genomewide CRISPR screen, we identified LZTR1, NF1, TSC1 and TSC2, negative regulators of the MAPK and MTOR pathways, as mediators of resistance to sorafenib. Analyses of ex vivo drug sensitivity assays in samples from patients with FLT3-ITD AML revealed that lower expression of LZTR1, NF1, and TSC2 correlated with sensitivity to sorafenib. Importantly, MAPK and/or MTOR complex 1 (MTORC1) activity was upregulated in AML cells made resistant to several FLT3 inhibitors, including crenolanib, quizartinib, and sorafenib. These cells were sensitive to MEK inhibitors, and the combination of FLT3 and MEK inhibitors showed enhanced efficacy, suggesting the effectiveness of such treatment in AML patients with FLT3 mutations and those with resistance to FLT3 inhibitors.
Epigenetic changes in human model KMT2A leukemias highlight early events during leukemogenesis
Authors: Milan Thomas , Celton Magalie , Lagacé Karine , Roques Élodie , Safa-Tahar-Henni Safia , Bresson Eva , Bergeron Anne , Hebert Josée , Meshinchi Soheil , Cellot Sonia , Barabé Frédéric , Wilhelm Brian T
Published: December 2020

Chromosomal translocations involving the KMT2A gene are among the most common genetic alterations found in pediatric acute myeloid leukemias although the molecular mechanisms that initiate the disease remain incompletely defined. To elucidate these initiating events we used a human model system of acute myeloid leukemia driven by the KMT2A-MLLT3 (KM3) fusion. More specifically, we investigated changes in DNA methylation, histone modifications, and chromatin accessibility at each stage of our model system and correlated these with expression changes. We observed the development of a pronounced hypomethyl - ation phenotype in the early stages of leukemic transformation after KM3 addition along with loss of expression of stem-cell-associated genes and skewed expression of other genes, such as S100A8/9, implicated in leukemogenesis. In addition, early increases in the expression of the lysine demethylase KDM4B was functionally linked to these expression changes as well as other key transcription factors. Remarkably, our ATAC-sequencing data showed that there were relatively few leukemia-specific changes and that the vast majority corresponded to open chromatin regions and transcription factor clusters previously observed in other cell types. Integration of the gene expression and epigenetic changes revealed that the adenylate cyclase gene ADCY9 is an essential gene in KM3-acute myeloid leukemia, and suggested the potential for autocrine signaling through the chemokine receptor CCR1 and CCL23 ligand. Collectively, our results suggest that KM3 induces subtle changes in the epigenome while co-opting the normal transcriptional machinery to drive leukemogenesis.
Relationship Interests, Motivation and Attention Parents of Biology Student Learning Outcomes Race: Passage of Interest in SMA Negeri Percut Sei Tuan
Authors: Zuhra Laina , Silitonga Melva , Subdibyo Mufti
Published: December 2020

This study aims to determine: (1) Biology learning outcomes of students; (2) Student interest in learning; (3) student motivation; (4) Parents' attention; (5) The relationship between interest, motivation and parental attention to student biology learning outcomes in the cross-interest group of class X students. This research was conducted at SMA Negeri 2 Percut Sei Tuan in 2019. The research method is a descriptive correlational research method with a research sample of 100 students. determined by cluster random sampling (random sample class). The research instrument consisted of a cognitive learning outcome test, a student interest questionnaire, a student learning motivation questionnaire, and a student parent attention questionnaire that had been tested for validity, reliability, discrepancy and level of difficulty. Data were analyzed using correlation analysis techniques using SPSS 21.0 for windows. The results showed: (1) Cognitive learning outcomes of 74.08 which fall into the moderate category; (2) The level of student interest was 64.67 which was in the medium category; (3) The level of student motivation is 68.46 which belongs to the medium category; (4) The level of attention of the students' parents is 66.74 which is in the moderate category; (5) The significant relationship between student interest in learning, student motivation, and parents' attention to student cognitive learning outcomes with Sig 0.00 <0.05.
Digital Identity
Authors: Majeed Mohamed Fareed Majeed  , Abdurahman Adisaputera  , Muhammad Ridwan
Published: December 2020

With the penetration and spread of the Internet in our daily life, issues related to our identity on the Internet and their potential impacts on our lives, whether positive or negative, have become very important. We, as individuals, interact with a number of websites and services on the Internet that require an account (username and password) to access. These sites range from simple news sites that limit the number of articles that you can read anonymously in a certain period of time, to financial services or healthcare sites or others. Similar services on the Internet require that you know with certainty that you are definitely "you" before granting you access to any private information. Of course, we want them to confirm our identity before allowing access to this type of very sensitive information, which can be used to inflict harm. Take us in different ways if you fall into the wrong hands. The presence in the virtual world has formed the digital identity, and this digital identity has different effects on the morals and habits of the users in this virtual world. Because of the existence of a digital identity, you may also be exposed to some type of privacy crime. In this case, we must study and adapt to create patterns of coexistence and resilience in the digital environment.
Public Service Satisfaction Licensing in Deli Serdang Regency
Authors: Nufaris Elisa
Published: December 2020

This study aims to determine the satisfaction of public service in the field of licensing Deli Serdang regency. Location of the research conducted in the area of Deli Serdang regency government is the reason for this is a site selection study for Deli Serdang regency. This study uses secondary data sources as the primary data source, which is equipped with a primary data source as a supporter. Sources of data mainly obtained from the Department of Commerce Office of P2KPM and Deli Serdang regency. The results showed that people's satisfaction of public services in Deli Serdang regency values obtained cumulative index of 21.7 in the range of 17-23 (moderate), so it can be concluded that the implementation of public service in Deli Serdang Regency included in the rate being.
The Outcome of Vaginal Birth After One Caesarean Section (VBAC)
Authors: Akter Mst Jesmin , Shirin Eliza
Published: December 2020

Background: Caesarean section has become the most performed major operation in obstetrics. The increasing rate of primary caesareans section becomes high worldwide due to early detection of fetal and maternal complications. Repeated caesarean section is one of the major contributory factors for increasing this rate very significantly. Now a day, vaginal delivery of pregnant mothers with the history of previous one caesarean with non-recurrent cause was established. It has been shown that the outcome of trial of labor in past caesarean delivery is acceptable, effective and safe for both mother and fetus, if the women are properly selected.

Objective: The objectives of this study were to determine the outcomes of vaginal birth after caesarean section (VBAC) in case of previous one caesarean section to reduce the subsequence cesarean section with its complication.

Materials and Methods: It was a cross sectional study carried out in the Maternity Unite-1, Department of Gynecology & Obstetrics, Sir Salimullah Medical College and Mitford hospital, Dhaka, Bangladesh, held on January 2010 to December 2010. Out of total 380 admitted pregnant women who had previous one caesarean section, 50 pregnant women of 37-42 weeks of gestational age with the history of one caesarean delivery with alive baby were selected as study population following consecutive and purposive sampling method. Patients with spontaneous onset labor but preterm pregnancy with any contraindication or prior caesarean section due to recurrent causes, history of classical caesarean section, more than one caesarean section, multiple pregnancy, pregnancy with medical disorder were excluded in the study.

Results: Out of total 50 sampled pregnant women, vaginal delivery were done 16(32%) & emergency cesarean section were done 34(68%). According to the age group both vaginal & cesarean section 20- 30 years were predominant, which were 8(50%) and 17(50%) respectively. Regarding antenatal care 13(81.25%) of vaginal delivery cases were regular. On the other hand, only 10(29.41%) of cesarean section were regular in care. Fetal survival outcome in vaginal & caesarean were 14(87.5%) and 33(97.05%) respectively. Comparing the maternal complication maximum number of vaginal delivery group had no complications.

Conclusion: It has been seen in this study that good antenatal care is of paramount importance and was associated with higer rate of vaginal delivery is pregnancy with history of one caesarean section. In this series the post Partum hemorrhage was higher in vaginal delivery group and wound infection rate was high in caesarean group.

J Bangladesh Coll Phys Surg 2021; 39(1): 36-45
Polycystic Ovary Syndrome and its Relationship with Infertility and its Management
Authors: Jahan Zakia , Wing Kirsten Elyse
Published: December 2020

Polycystic ovary syndrome (PCOS) is the most common and treatable endocrine dysfunction in fertile women. The pathophysiology of PCOS involves primary defects in the hypothalamic–pituitary axis, insulin secretion and action, and ovarian function.Studies show 20-40 percent of female first-degree relatives of women with PCOS also have the syndrome.Genetic studies have identified a link between PCOS and disordered insulin metabolism and hyperinsulinemia.PCOS is characterized by hyperandrogenism, irregular ovulatory cycle and metabolic derangement, including glucose intolerance and hyperinsulinemia. Hyperandrogenism is a clinical hallmark of PCOS.In women with PCOS, Ovulation problems are usually the primary cause of infertility. PCOS is the most common cause of anovulatory infertility; ∼ 90–95% of women seeking treatment for infertility have PCOS. PCOS may cause higher risk for infertility, type 2 diabetes, high blood pressure, and endometrial cancer. The most common symptoms are irregular period, weight gain, acne, and excessive facial and body hair. PCOS has no cure but there are multiple treatments that can reduce symptoms. Life style modification includingdiet and exercise, have shown a positive influence on women with PCOS.

J Bangladesh Coll Phys Surg 2021; 39(1): 53-58
Secondary Metastatic Gastric Melanoma
Authors: Chowdhury Abdullah Al Mamun , Khan Meshkat Uddin , Hussain Md Margub
Published: December 2020

Gastrointestinal melanomas are commonly metastatic from a cutaneous origin. They cause significant cancer related mortality. A 47- year - old male patient presented with severe pallor and prostration due to profuse upper GI bleeding. He was urgently managed with fluid and blood transfusion. Endoscopy revealed gastric mass and CT showed gastric neoplasm with abdominal lymphadenopathy but endoscopic biopsy revealed inflammatory lesion. He had history of malignant melanoma of right third toe three years back which was managed with surgery and chemotherapy. Exploratory laparotomy was done and biopsy was taken from gastric lesion as well as enlarged lymph nodes. Histopathology revealed melanoma from both specimens. Prognosis is bad. Counseling and collaboration with different relevant disciplines are essential. Management is directed to symptom relieve as well as lengthening survival.

J Bangladesh Coll Phys Surg 2021; 39(1): 68-75
Valoración económica del Área de Conservación Regional Vilacota Maure: Servicios ecosistémicos priorizados al extremo sur del Perú
Authors: Navarro Marco , Guillen Claudio , Limache Leónidas
Published: December 2020

A pesar de la importancia que tienen los bienes y servicios ecosistémicos en la economía mundial, en la gestión del Área de Conservación Regional Vilacota Maure en el departamento de Tacna aún se mantienen desfasados paradigmas de uso irracional de recursos y de sobreexplotación, manifestándose en grandes presiones y amenazas a los ecosistemas, contrarias a sus objetivos de conservación. Es por ello que en una reunión de expertos (focus group), se priorizó valorizar económicamente a tres servicios ecosistémicos que representan mejor su importancia: provisión de recurso hídrico, el secuestro de carbono y provisión de recursos genéticos o forraje ganadero. Para la determinación de la valoración económica de estos servicios se aplicó el método preferencias reveladas y de precios de mercado, resultando $ 1 749 548.65, $ 454 938.55 y $ 1 461 388.35 respectivamente. Asimismo, también se valorizó en función a su potencial de desarrollo a través del método de preferencias reveladas y respectivamente en base a costos evitados, precios de mercado y función de producción, resultando los valores de $ 3 844 682.73, $ 454 938.55 y $ 7 254 869.32 respectivamente.
Visión de la gestión del cuidado del profesional de enfermería en el primer nivel de atención de las microredes de salud de Tacna
Authors: Mutter Cuellar Karimen Jetzabel , Cachicatari Vargas Elena
Published: December 2020

Objetivo: Analizar el significado de la visión de la gestión del cuidado de los profesionales de enfermería que trabajan en el primer nivel de atención de las micro redes de salud de Tacna. El escenario tomó lugar en la provincia y ciudad de Tacna. Los participantes fueron 07 profesionales de enfermería con cargo o experiencia en Jefatura de las micro redes y establecimientos de salud. Material y métodos: Estudio cualitativo de teoría fundamentada. La técnica fue la entrevista a  profundidad y como instrumento una guía de entrevista semiestructurada. La muestra se obtuvo del muestreo teórico por saturación de datos. Resultados: En el análisis de la información se utilizó el método de teoría fundamentada mediante el proceso de codificación abierta, axial y selectiva en el que emergieron cinco categorías, 13 subcategorías y 28 unidades de análisis. La primera categoría estuvo relacionada a los conceptos disciplinarios; la segunda, al juicio profesional de la gestión del cuidado; como tercera categoría, se consideró la competencia del profesional de enfermería para la gestión del cuidado; la cuarta categoría estuvo en relación con la comunidad; finalmente, la quinta categoría fue sobre liderazgo. De ellas emergió la teoría que representa la visión de la gestión del cuidado. Conclusiónes: La teoría emergente que representa la visión de la gestión del cuidado considera al profesional de enfermería del primer nivel de atención  como líder con conocimientos, empoderado y actualizado en la práctica del cuidado dirigida a la persona, familia y comunidad con actitud empática y asertiva.
Síndrome del túnel carpiano
Authors: Rodríguez Menéndez Abelardo Emilio , Gonzales Vargas María , Ticona Anahua Ronald , Campos Condori Helbert , Ucharico Chura Erick , Ramios Ccallo Joel , Calahuille Aycachi Yudith , Díaz Mamani Alan , Avalos Cueva Annie , Velasquez Nina Verónica , Cotrado Estalla Edith
Published: December 2020

El síndrome del túnel carpiano es una lesión compresiva del nervio mediano, multicausal. Es una  neuropatía periférica con manifestaciones sensitivas, motoras y tróficas, la cual afecta al paciente desde los puntos de vista biopsicosocial. Objetivo: Actualización de los conocimientos relacionados con el síndrome del túnel carpiano. Material y métodos: Se realizó una revisión bibliográfica de 120 autores nacionales e internacionales, y se extrajo una síntesis para facilitar los conocimientos de forma práctica a nuestros médicos, ya que esta es una patología frecuente en las consultas y es necesario conocerla para diagnosticarla correctamente. Desarrollo: Se muestra sobre el síndrome del túnel carpiano, su reseña histórica, recuento anatómico y fisiológico, su fisiopatología, cuadro clínico y estudios complementarios para confirmar el diagnóstico, así como los diferentes tipos de tratamientos desde el médico hasta el quirúrgico. Se mencionan los diferentes tipos de investigaciones que se realizan para su diagnóstico. Conclusiones: Esta identidad es motivo de consulta y tiende a confundirse o estar combinada con una discopatía cervical.