bluuebunny/crossref_metadata_2025 huggingface dataset:
Biodiversity, Ecology and Distribution of Mediterranean Charophytes in Southern Italy
Authors: Bellino Alessandro , Baldantoni Daniela
Published: September 2023

Charophytes are amongst the most endangered primary producers in freshwater and coastal ecosystems. In spite of the extensive research on the group and its ecological and conservational relevance, scarce information is available on Mediterranean environments, especially rivers and small water reservoirs, where charophytes face challenging summer droughts and changes in hydrological regimes, as well as pervasive anthropogenic pressures. This research aimed, through repeated field observations, detailed analyses of population traits, and extensive characterization of the colonized environments, to foster an understanding of the distribution, biodiversity, and ecology of charophytes in an area of exceptional environmental value and that is still uninvestigated in relation to its charophyte flora, the southern Campania region (Italy). Overall, 17 populations were discovered, belonging to 4 taxa of the Chara genus: C. globularis, C. gymnophylla, C. vulgaris, and C. vulgaris var. papillata, reduced to 12 populations and to the first 3 taxa by the end of the study. The species occupied different ecological niches and colonized environments such as rivers and small ponds, with environment-dependent morphotypes. The occurrence of few taxa with a wide distribution, often forming ephemeral populations, suggests ongoing constraints on charophyte biodiversity in the area, favoring opportunistic species that are able to benefit from temporary refugia.
Surge Process of a High-Speed Axial–Centrifugal Compressor
Authors: Li Jiaan , Wang Baotong , Zheng Xinqian
Published: September 2023

The surge is a typical aerodynamic instability phenomenon in the compression system, which can lead to serious consequences such as engine performance degradation and structural damage. A deep understanding of the surge process can support the development of a compressor with a wider operating range. In this paper, an experimental study was carried out and high-responding pressure sensors were used to obtain the aerodynamic instability process and the post-surge characteristics of an axial–centrifugal compressor at design and off-design speeds. The evolution of the flow field and instability behavior before and after the surge were analyzed. The results showed that the inlet temperature change can reflect the aerodynamic instability to some extent, and as the operating condition moves from the choke to surge boundary, the inlet temperature undergoes a sudden increase at a certain condition and further increases with the decrease in mass flow rate. At the design speed, the instability of the combined compressor featured a deep surge with an obvious rotating stall behavior before its inception, and the amplitude of the stall cell was gradually enhanced, finally leading to the surge. At the off-design speed, affected by the stage mismatching, the axial stage mainly worked near the unstable operating condition. Therefore, the compressor successively experiences two modes of mild surge and deep surge, and the rotating stall can also be observed during the surge cycle.
Tectonic Control on Shale Pore Structure and Gas Content from the Longmaxi Formation Shale in Southern Sichuan Basin, China: Insights from Fractal Analysis and Low-Pressure Gas Adsorption
Authors: Shi Xuewen , Liang Zhikai , Yang Yuran , Li Yi , Jiang Zhenxue , Li Yanyou , Li Runtong , Deng Feiyong
Published: September 2023

Tectonic deformation of different intensities significantly controls shale pore structure, seepage channels, and gas content. The Longmaxi Formation shales in the southern Sichuan Basin have experienced multi-stage tectonic movements, resulting in a diverse fracture system and tectonic deformation. This study focuses on three representative tectonic morphologies: deeply buried strongly deformed (DBSD), deeply buried weakly deformed (DBWD) and shallowly buried weakly deformed (LBWD). We investigated the pore structure characteristics and heterogeneity of these shales under various tectonic conditions using total organic carbon (TOC) content, X-ray diffraction (XRD), scanning electron microscopy (SEM), a low-pressure N2/CO2 adsorption experiment (LP-N2/CO2 GA), and multi-scale fractal theory. The results reveal that strong tectonic compression and deformation conditions lead to the compression and flattening of organic pores by brittle minerals, resulting in long, oriented OM pores. Fracturing of brittle pore creates multiple internal fracture systems linked to dissolution pores, forming a complex micro-fracture–pore network. With intense tectonic deformation, mesopores tend to be compressed, increasing micropore pore volume (PV) and surface area (SA). The DBSD shale exhibits the highest micropore heterogeneity, while the LBWD shale shows the lowest heterogeneity. Fractal analysis indicates a significant decrease in micropore fractal dimension (Df) with increasing burial depth. In contrast, the surface and matrix fractal dimensions (Ds and Dm) of low-buried shale micropores and meso-macropores align vertically. Shale reservoirs in tectonically stable regions exhibit more favourable gas-bearing characteristics than strongly tectonically deformed areas. The LBWD has stable tectonic conditions that are favourable for shale gas preservation. Conversely, slip faults under deep burial conditions lead to extrusion and deformation of shale pore space, ultimately compromising the original reservoir capacity and hindering shale gas enrichment. These findings contribute significantly to our understanding of pore structure and heterogeneity in tectonically deformed shale reservoirs, providing invaluable guidance for the exploration, development, and prediction of shale gas resources.
Is Less More? Reevaluating the Psychometric Properties of the Sense of Coherence-13 and a Revised Seven-Item Version in South Africa Using Classical Theory and Item Response Theory
Authors: Pretorius Tyrone B. , Padmanabhanunni Anita
Published: September 2023

Studies on the dimensionality and factor structure of the Sense of Coherence-13 (SOC-13) scale have produced inconsistent results, and there is a need for comprehensive psychometric testing of the scale in different populations and using diverse methodologies. SOC refers to the individual’s ability to perceive life as comprehensible, manageable, and meaningful. The current study investigated the dimensionality of the SOC-13 through the use of confirmatory factor analysis (CFA), ancillary bifactor indices and item response theory in a sample of young adults in South Africa. Participants were students (n = 322) who completed the SOC-13, the Connor–Davidson Resilience Scale, the PTSD Checklist for DSM-5 and short forms of the Center for Epidemiological Studies Depression Scale, and the trait scale of the Spielberger State-Trait Anxiety Inventory. CFA indicated the best fit for a one-factor model, but the problematic parameter estimates raise concerns about the construct validity of the scale. Non-parametric item response theory (Mokken scale analysis [MSA]) identified limitations in the original 13-item version, suggesting a more dependable seven-item version (SOC-7). This revised scale exhibited strong psychometric characteristics and was consistent with the theoretical foundations that underpin the construct. We verified the unidimensional structure of the SOC with the more stringent parametric item-response theory (Rasch analysis) which confirmed that the seven-item SOC is unidimensional. Rasch analysis confirmed the measurement invariance of the SOC-13 in terms of gender and area of residence. The study suggests that a shorter seven-item version consisting of items from the three components of sense of coherence has comparative properties to the 13-item version but the evidence does not provide support for the use of the SOC-13 as a multidimensional measure. Research in the area of sense of coherence would benefit from further validation studies of both the original SOC-13 and the revised SOC-7, especially across populations and settings.
Should Selection of the Optimum Stochastic Mortality Model Be Based on the Original or the Logarithmic Scale of the Mortality Rate?
Authors: Santolino Miguel
Published: September 2023

Stochastic mortality models seek to forecast future mortality rates; thus, it is apparent that the objective variable should be the mortality rate expressed in the original scale. However, the performance of stochastic mortality models—in terms, that is, of their goodness-of-fit and prediction accuracy—is often based on the logarithmic scale of the mortality rate. In this article, we examine whether the same forecast outcomes are obtained when the performance of mortality models is assessed based on the original and log scales of the mortality rate. We compare four different stochastic mortality models: the original Lee–Carter model, the Lee–Carter model with (log)normal distribution, the Lee–Carter model with Poisson distribution and the median Lee–Carter model. We show that the preferred model will depend on the scale of the objective variable, the selection criteria measure and the range of ages analysed.
Citizen Laboratories as Scenarios of Cultural and Political Democratization
Authors: Giraldo Gutiérrez Francisco Luis , De Jesús Toro Ríos Henry , Perlaza Lopera Carolina , Mejía Upegui Juan Esteban
Published: September 2023

The inefficiency of states in meeting their populations’ needs poses a deterrent to citizen participation. Within this context, an inquiry into the impact of citizen laboratories on urban governance becomes pertinent. Democracy necessitates innovation to ascertain solutions by harmonizing technology, knowledge, design, planning, and the social sciences. Citizen laboratories foster this equilibrium, thereby enabling the effective exercise of popular governance. Furthermore, they empower individuals to cultivate their civic conduct grounded in five pivotal concepts: the political, the politic, the policy, the culture, and the cultural. This contributes to urban sustainability and engenders the consolidation of identity, principles, ideals, memory, and the social fabric. By means of a literature review, an examination can be undertaken guided by the foundational premises that shape the distinctive attributes of citizen laboratories. This endeavor proves valuable in extending the discourse, as authentic and unfeigned citizen involvement in decision-making processes for their communities emerges as an indispensable factor.
Molecular Evolution of Dengue Virus 3 in Senegal between 2009 and 2022: Dispersal Patterns and Implications for Prevention and Therapeutic Countermeasures
Authors: Dieng Idrissa , Balde Diamilatou , Talla Cheikh , Camara Diogop , Barry Mamadou Aliou , Sagne Samba Niang , Gueye Khadim , Dia Cheikh Abdou Khadre Mbacké , Sambe Babacar Souleymane , Fall Gamou , Sall Amadou Alpha , Faye Ousmane , Loucoubar Cheikh , Faye Oumar
Published: September 2023

Dengue fever is the most prevalent arboviral disease worldwide. Dengue virus (DENV), the etiological agent, is known to have been circulating in Senegal since 1970, though for a long time, virus epidemiology was restricted to the circulation of sylvatic DENV−2 in south-eastern Senegal (the Kedougou region). In 2009 a major shift was noticed with the first urban epidemic, which occurred in the Dakar region and was caused by DENV−3. Following the notification by Senegal, many other West African countries reported DENV−3 epidemics. Despite these notifications, there are scarce studies and data about the genetic diversity and molecular evolution of DENV−3 in West Africa. Using nanopore sequencing, phylogenetic, and phylogeographic approaches on historic strains and 36 newly sequenced strains, we studied the molecular evolution of DENV−3 in Senegal between 2009 and 2022. We then assessed the impact of the observed genetic diversity on the efficacy of preventive countermeasures and vaccination by mapping amino acid changes against vaccine strains. The results showed that the DENV−3 strains circulating in Senegal belong to genotype III, similarly to strains from other West African countries, while belonging to different clades. Phylogeographic analysis based on nearly complete genomes revealed three independent introduction events from Asia and Burkina Faso. Comparison of the amino acids in the CprM-E regions of genomes from the Senegalese strains against the vaccine strains revealed the presence of 22 substitutions (7 within the PrM and 15 within the E gene) when compared to CYD-3, while 23 changes were observed when compared to TV003 (6 within the PrM and 17 within the E gene). Within the E gene, most of the changes compared to the vaccine strains were located in the ED-III domain, which is known to be crucial in neutralizing antibody production. Altogether, these data give up-to-date insight into DENV−3 genomic evolution in Senegal which needs to be taken into account in future vaccination strategies. Additionally, they highlight the importance of the genomic epidemiology of emerging pathogens in Africa and call for the implementation of a pan-African network for genomic surveillance of dengue virus.
Evaluation of Cross-Immunity to the Mpox Virus Due to Historic Smallpox Vaccination
Authors: Matusali Giulia , Petruccioli Elisa , Cimini Eleonora , Colavita Francesca , Bettini Aurora , Tartaglia Eleonora , Sbarra Settimia , Meschi Silvia , Lapa Daniele , Francalancia Massimo , Bordi Licia , Mazzotta Valentina , Coen Sabrina , Mizzoni Klizia , Beccacece Alessia , Nicastri Emanuele , Pierelli Luca , Antinori Andrea , Girardi Enrico , Vaia Francesco , Sette Alessandro , Grifoni Alba , Goletti Delia , Puro Vincenzo , Maggi Fabrizio
Published: September 2023

When the Mpox virus (MPXV) began spreading globally in 2022, it became critical to evaluate whether residual immunity from smallpox vaccination provided cross-protection. To assess the cross-immune response to MPXV, we collected serum samples (n = 97) and PBMCs (n = 30) from healthy-donors, either born before 1974 and reporting smallpox vaccination during childhood or born after 1975 and not vaccinated with Vaccinia virus (VACV)-based vaccines. We evaluated the levels of anti-MPXV IgG and neutralizing antibodies (Nabs) and the presence of a T cell response against MPXV. We found anti-MPXV IgG and Nabs in 60 (89.6%) and 40 (70.1%) vaccinated individuals, respectively. We observed a T cell response to Orthopoxviruses and MPXV peptide pools in 30% of vaccinated individuals. We thus show that a high proportion of subjects who received the smallpox vaccine 40 to 60 years ago have humoral cross-immunity, while the T-cell-specific response against MPXV was observed in a smaller group (30%) of vaccinated individuals. This study, combined with information on immunity developed during natural infection or the administration of current vaccines, will contribute to a better understanding of humoral and cellular responses against MPXV.
MDA5 with Complete CARD2 Region Inhibits the Early Replication of H9N2 AIV and Enhances the Immune Response during Vaccination
Authors: Li Tongtong , Cai Yiqin , Li Chenfei , Huang Jingwen , Chen Jiajing , Zhang Ze , Cao Ruibing , Zhou Bin , Feng Xiuli
Published: September 2023

Chicken melanoma differentiation-associated gene 5 (MDA5) is a member of the RLRs family that recognizes the viral RNAs invading cells and activates downstream interferon regulatory pathways, thereby inhibiting viral replication. The caspase activation and recruitment domain (CARD) is the most important region in MDA5 protein. However, the antiviral and immune enhancement of MDA5 with the CARD region remains unclear. In this study, two truncated MDA5 genes with different CARD regions, namely MDA5-1 with CARD1 plus partial CARD2 domain and MDA5-2 with CARD1 plus complete CARD2 domain, were cloned via reverse transcription PCR and ligated into plasmid Flag-N vector to be Flag-MDA5-1 and Flag-MDA5-2 plasmids. DF-1 cells were transfected with two plasmids for 24 h and then inoculated with H9N2 virus (0.1 MOI) for 6 h to detect the levels of IFN-β, PKR, MAVS, and viral HA, NA, and NS proteins expression. The results showed that MDA5-1 and MDA5-2 increased the expression of IFN-β and PKR, activated the downstream molecule MAVS production, and inhibited the expression of HA, NA, and NS proteins. The knockdown of MDA5 genes confirmed that MDA5-2 had a stronger antiviral effect than that of MDA5-1. Furthermore, the recombinant proteins MDA5-1 and MDA5-2 were combined with H9N2 inactivated vaccine to immunize SPF chickens subcutaneously injected in the neck three times. The immune response of the immunized chicken was investigated. It was observed that the antibody titers and expressions of immune-related molecules from the chicken immunized with MDA5-1 and MDA5-2 group were increased, in which the inducing function of MDA5-2 groups was the highest among all immunization groups. These results suggested that the truncated MDA5 recombinant proteins with complete CARD2 region could play vital roles in antiviral and immune enhancement. This study provides important material for the further study of the immunoregulatory function and clinical applications of MDA5 protein.
Clinical Applications of Combined Immunotherapy Approaches in Gastrointestinal Cancer: A Case-Based Review
Authors: Eralp Yesim , Ates Utku
Published: September 2023

Malignant neoplasms arising from the gastrointestinal (GI) tract are among the most common types of cancer with high mortality rates. Despite advances in treatment in a small subgroup harboring targetable mutations, the outcome remains poor, accounting for one in three cancer-related deaths observed globally. As a promising therapeutic option in various tumor types, immunotherapy with immune checkpoint inhibitors has also been evaluated in GI cancer, albeit with limited efficacy except for a small subgroup expressing microsatellite instability. In the quest for more effective treatment options, energetic efforts have been placed to evaluate the role of several immunotherapy approaches comprising of cancer vaccines, adoptive cell therapies and immune checkpoint inhibitors. In this review, we report our experience with a personalized dendritic cell cancer vaccine and cytokine-induced killer cell therapy in three patients with GI cancers and summarize current clinical data on combined immunotherapy strategies.
Immunogenicity and Pre-Clinical Efficacy of an OMV-Based SARS-CoV-2 Vaccine
Authors: Grandi Alberto , Tomasi Michele , Ullah Irfan , Bertelli Cinzia , Vanzo Teresa , Accordini Silvia , Gagliardi Assunta , Zanella Ilaria , Benedet Mattia , Corbellari Riccardo , Di Lascio Gabriele , Tamburini Silvia , Caproni Elena , Croia Lorenzo , Ravà Micol , Fumagalli Valeria , Di Lucia Pietro , Marotta Davide , Sala Eleonora , Iannacone Matteo , Kumar Priti , Mothes Walther , Uchil Pradeep D. , Cherepanov Peter , Bolognesi Martino , Pizzato Massimo , Grandi Guido
Published: September 2023

The vaccination campaign against SARS-CoV-2 relies on the world-wide availability of effective vaccines, with a potential need of 20 billion vaccine doses to fully vaccinate the world population. To reach this goal, the manufacturing and logistic processes should be affordable to all countries, irrespective of economical and climatic conditions. Outer membrane vesicles (OMVs) are bacterial-derived vesicles that can be engineered to incorporate heterologous antigens. Given the inherent adjuvanticity, such modified OMVs can be used as vaccines to induce potent immune responses against the associated proteins. Here, we show that OMVs engineered to incorporate peptides derived from the receptor binding motif (RBM) of the spike protein from SARS-CoV-2 elicit an effective immune response in vaccinated mice, resulting in the production of neutralizing antibodies (nAbs) with a titre higher than 1:300. The immunity induced by the vaccine is sufficient to protect the animals from intranasal challenge with SARS-CoV-2, preventing both virus replication in the lungs and the pathology associated with virus infection. Furthermore, we show that OMVs can be effectively decorated with the RBM of the Omicron BA.1 variant and that such engineered OMVs induce nAbs against Omicron BA.1 and BA.5, as measured using the pseudovirus neutralization infectivity assay. Importantly, we show that the RBM438–509 ancestral-OMVs elicited antibodies which efficiently neutralize in vitro both the homologous ancestral strain, the Omicron BA.1 and BA.5 variants with a neutralization titre ranging from 1:100 to 1:1500, suggesting its potential use as a vaccine targeting diverse SARS-CoV-2 variants. Altogether, given the convenience associated with the ease of engineering, production and distribution, our results demonstrate that OMV-based SARS-CoV-2 vaccines can be a crucial addition to the vaccines currently available.
Changes in Invasive Pneumococcal Disease in the Paediatric Population in the Second COVID-19 Pandemic Year
Authors: Izquierdo Conchita , Ciruela Pilar , Soldevila Núria , Garcia-Garcia Juan-Jose , Gonzalez-Peris Sebastia , Díaz-Conradi Alvaro , Viñado Belen , F de Sevilla Mariona , Moraga-Llop Fernando , Muñoz-Almagro Carmen , Domínguez Angela ,   Barcino Working Group
Published: September 2023

Incidence of invasive pneumococcal disease (IPD) decreased worldwide in 2020, coinciding with the implementation of measures to reduce COVID-19 transmission. We evaluated the impact of the COVID-19 pandemic on healthcare demand and IPD in children in 2021 compared to the pre-pandemic period (2018–2019) and the early pandemic period (2020) in a study carried out during 2018–2021 in Catalonia. Incidence rates were compared by calculating the incidence rate ratio (IRR), and expressing percentage changes in IRR as (1-IRR)x100. Compared to 2018–2019, emergency room (ER) visits declined by 21% in 2021 (p < 0.001), mainly in the first quarter (−39%), and compared to 2020, ER visits increased by 22% in 2021 (p < 0.001), except in the first quarter. IPD incidence overall was 11.0 in 2018–2019 and 4.6 in 2021 (−58%, p < 0.001); the reduction in incidence was similar in the 0–4 age group and was higher in the first quarters. Compared to 2020, in 2021, IPD incidence decreased during the first quarter (−86%, p < 0.001), but increased from 0.0 to 1.2 in the second quarter (p = 0.02) and from 0.6 to 2.1 (p=0.03) in the fourth quarter. The decreased IPD incidence observed in 2021 compared to 2018–2019 (most especially in the first quarter) was greater than the decrease in healthcare demand and PCR test requests. Compared to 2020, IPD incidence decreased in the first quarter when a second state of alarm was in force. In 2021, compared to 2018–2019, there was a greater reduction in PCV13 serotypes than in non-PCV13 serotypes.
La rétinopathie du border collie, une maladie héréditaire mais un gène difficile à isoler
Authors: Chaudieu Gilles , Quignon Pascale
Published: September 2023

Some Border Collies, essentially males on average 4-year-old, exhibit focal or generalized retinal atrophic lesions. A following survey revealed progressive lesions and histopathology examination confirmed retinal degeneration. The hypothesis of a X-linked inheritance is supported by a genetic linkage study highlighting the X chromosome. Whole genome sequencing («short read » ) of several dogs identifies variants segregating as expected. The «long read » would allow the identification of structural variants. Variability in the phenotype might induce difficulties to point out common variants in affected dogs. Thus, a strict selection of the cases has been performed. In addition, the selection of breeding dogs on the basis of the X-linked inheritance by the French Border Collie Kennel Club enabled to decrease the frequency of the affected dogs from 20% (2001) to 7,4% (2019).
Creativity and Cognitive Niche Construction in Salvatore Sciarrino’s L’opera per flauto
Authors: Castello Branco Marta , Queiroz João
Published: September 2023

The emergence of new musical ideas, and new forms of musicality, is described here as the transformation of conceptual spaces in a cognitive niche, a distributed and self-organised set of intergenerational concepts, materials, and actions. According to this approach, there is a direct co-dependence relation, a co-evolutionary causal looping, between new, acceptable (valid) and surprising musical ideas (which define what is creative in a certain context), agents, tools and artifacts (instruments, musical notations, types of equipment, performance space), and conceivable epistemic and pragmatic actions (instrument techniques, dynamics of collaboration, scenic procedures). This co-evolutionary relation defines a conceptual space of musicality. To demonstrate our thesis, we detail the development of extended techniques for transverse flute, a phenomenon strongly dependent on performer-composer collaboration. We focus on Salvatore Sciarrino’s L’opera per flauto (1990), which was developed in an intensive work with the flautist Roberto Fabbriciani, through investigation of sounding possibilities of the instrument. The collaboration resulted in new and surprising sounds for the transverse flute, including the combination of extended techniques, and their notation, largely applied by later repertoire.
Elevating Thyme Species Identification: Exploiting Key Chloroplast Genes (matK, rbcL, and psbA-trnH) through DNA Barcoding and Phylogenetic Analysis
Authors: FURAN M. Alp
Published: September 2023

Understanding genetic relationships and diversity among species is crucial for unraveling evolutionary processes, ecological interactions, and conservation strategies. DNA sequence analysis serves as a powerful tool in this endeavor. This study focuses on the Thymus genus, a collection of notable species, to investigate its genetic framework. Leveraging DNA sequences from key regions (matK, rbcL, and psbA-trnH), we aim to elucidate genetic connections within the Thymus genus and uncover mechanisms driving its diversity. The Thymus genus, with its diverse species and ecological characteristics, provides a captivating platform for genetic exploration. Through DNA sequence analysis, we aim to unveil genetic interconnections, biodiversity patterns, and the factors shaping the genus's evolution. Our findings are aligned with previous studies, and this consistency highlights the presence of polymorphism within potential sequences. Employing coding loci and spacer regions, our study contributes to Lamiaceae family barcoding research. Despite variations across gene regions, the concatenation of sequences enhances result reliability. We analyzed the suitability of matK, rbcL, and psbA sequences for Thymus identification, observing rbcL and psbA outperforming matK. Our novel approach, rooted in chloroplast DNA, presents a promising method for species discernment. By analyzing multiple chloroplast gene regions, this technique offers a fresh perspective on genetic affinity assessment using DNA barcodes. In conclusion, this study not only contributes to Thymus germplasm resource preservation but also exemplifies a novel approach to discerning Thymus species through DNA analysis. This methodology carries the potential for broader application, enriching our understanding of genetic relationships and diversity in the plant kingdom.
ORIENTACJA APERCEPCYJNA CZY ZADANIOWA – DLACZEGO POKOLENIE FACEBOOKA CZUJE SIĘ TAK WYALIENOWANE I BEZUŻYTECZNE
Authors: Pospiszyl Irena
Published: September 2023

Współczesne zmiany cywilizacyjne, szczególnie zaś upowszechnienie się sieci społecznościowych, sprawiły, że umiejętność autoprezentacji stała się głównym źródłem powodzenia w świecie społecznym. Procesy te niejako w naturalny sposób przekierowały uwagę jednostki z otoczenia i aktywności, jaką zwykle uprawiała, na nią samą i budowanie własnej atrakcyjności w grupie. Te zmiany w postrzeganiu własnej osoby i własnych relacji ze światem społecznym nazywam orientacją apercepcyjną Spowodowała ona cały szereg konsekwencji, m.in. dotyczących priorytetów w zakresie własnej aktywności, dominujących mechanizmów regulacji samooceny, czy punktów odniesienia dla osobistych dążeń. Przedmiotem szczególnej uwagi stało się nie działanie, a stan emocjonalny. Artykuł traktuje o zmianach w mentalności młodzieży, jakie spowodowała powszechna obecność sieci społecznościowych, typowych pułapkach, w jakie wpadają opiekunowie, psychologowie i inni dorośli, zaniepokojeni rosnącą skalą depresji i poczucia wyalienowania, oraz zawiera propozycję odwrócenia tego niekorzystnego trendu.
IMPLEMENTASI METODE AHP DAN MAUT UNTUK REKOMENDASI PRODUK TUPPERWARE TERLARIS
Authors: Okmarizal Bisma , Defit Sarjon , Sumijan
Published: September 2023

Untuk melakukan pemesanan barang tupperware pada unit simabur indah, sering terjadi ketidaksesuaian antara permintaan barang dengan barang yang di pesan sehingga terjadinya penumpukan barang dan kekosongan stok barang. Untuk meningkatkan efektifitas jual beli maka dibutuhkanlah sebuah sistem informasi untuk rekomendasi barang terlaris sebagai pendukung keputusan. Metode yang digunakan adalah AHP dan MAUT, pembuat keputusan adalah 5 star manager dan data yang digunakan adalah data katalog bulan maret 2023 sebanyak 20 data dan kriteria yang digunakan adalah 6 kriteria. Implementasi metode AHP dan MAUT menghasilkan A9, A20, A8, A13, A7 dengan nilai 0,916077, 0,842113, 0,831385, 0,768166, 0,768166 sebagai alternatif yang disarankan untuk pembelian di bulan berikutnya. Dengan membandingkan antara keputusan perusahaan didapatkanlah satu hasil rekomendasi yang berbeda sehingga akurasi didapatkan sebanyak 80%.
Influence of Instagram Social Media Marketing as a Promotional Means to Increase Intentions to Visit Tourist Destinations
Authors: Fitri Fadhilla Resta , Februadi Agustinus , Elisabeth Vera , Yuardani Ade Muhamad
Published: September 2023

Technological advances, mainly social media, can drive the increase in GDP. The ease, convenience, and practicality of consumers using social media create almost limitless opportunities for social media marketing in the travel sector. Tourism destination managers have widely used Instagram to promote their destinations by creating appropriate images. However, it is essential to understand the types of destination images that influence tourists. This research aims to understand the relationship between destination image and intention in social media marketing. This research also aims to determine which cognitive or affective destination description is more significant. This research involved 373 respondents who actively use Instagram and know tourism destinations' official social media accounts. The data was analyzed using PLS-SEM. This research finds that social media marketing significantly affects the intention to visit, affective, and cognitive destination images. Destination image also mediates the relationship between social media marketing and visitors' propensity to leave. The analysis findings also show that affective destination image is more effective than cognitive destination image in influencing visitor intentions. These results highlight the importance of considering emotional components when promoting tourist locations.
PEMILIHAN SUPPLIER MINYAK JELANTAH BAHAN BAKU BIOSOLAR DENGAN METODE ELECTRE
Authors: Anatasya Dita Riyantiin , Andriyanto Teguh , Firliana Rina , Sucipto
Published: September 2023

CV. Fred Jelantah is a CV engaged in the industrial sector, namely suppliers of used cooking oil as raw material for biodiesel. In the process of meeting the needs for supply of goods, CV.Fred Jelantah requires more than one supplier. So far, CV. Fred Jelantah still uses a subjective process in considering supplier selection. This causes inaccuracies in the supply of goods such as oil quality and timeliness of supply. The research objective of modeling a decision support system using the ELECTRE method is to be able to provide the best supplier references accurately and subjectively unconventionally for CV. Fred Jelantah. In calculating the ELECTRE method, 4 alternatives and 5 criteria are determined. Based on the results of the research conducted, the highest ranking results were obtained, namely the Jelantah Kelud and Kuli Jelantah alternatives with a total value of 1.
Predyktory poczucia opuszczenia przez Boga u katolików w Polsce: analiza codziennych doświadczeń religijno­ ‑duchowych i moderująca rola poziomu deklarowanej wiary
Authors: Prusak Jacek , Wasiewicz Jakub
Published: September 2023

CEL NAUKOWY: Celem prezentowanych badań było ukazanie predyktorów i moderatorów poczucia opuszczenia przez Boga jako jednego z doświadczeń religijno-duchowych katolików.

PROBLEM I METODY BADAWCZE: Zasadniczym zagadnieniem badawczym było określenie, jaki, jeśli w ogóle, istnieje związek pomiędzy wiekiem, poziomem deklarowanej wiary, częstotliwością i intensywnością codziennych doświadczeń religijno-duchowych a poczuciem opuszczenia przez Boga.

PROCES WYWODU: W artykule omówiono psychologiczną konceptualizację poczucia opuszczenia przez Boga oraz jego operacjonalizację w narzędziach badawczych, a także wagę tej problematyki dla badań nad zmaganiami z boskością.

WYNIKI ANALIZY NAUKOWEJ: Na podstawie statystycznej weryfikacji hipotez badawczych zbadano zależności pomiędzy przyjętymi zmiennymi i ustalono predyktory i moderatory związków pomiędzy zmienną wyjaśnianą a zmiennymi wyjaśniającymi.

WNIOSKI, INNOWACJE, REKOMENDACJE: Choć wszystkie przyjęte hipotezy uzyskały statystyczne potwierdzenie, tak że udało się wskazać predyktor i moderator poczucia opuszczenia przez Boga, w artykule wskazano ograniczenia niniejszego badania i kierunki dalszych badań.
Effect of the thicknesses of asymmetric TiO2/polydimethylsiloxane films on the triboelectric output power
Authors: Zhou Qingyang , Ikuno Takashi
Published: September 2023

To improve the output voltage of the polydimethylsiloxane (PDMS)-based triboelectric nanogenerators, we investigated the effect of thicknesses of TiO2 nanoparticles (NPs)/PDMS composite films on the output power. The composite film was composed of TiO2 NPs-embedded PDMS film (base film) and pure PDMS thin film (capping layer) which was deposited on the base film. We found that the moderate thickness of the capping layer was approximately 3 μm, which is the thinnest film thickness that can completely cover the particulates exposed on the surface. The TiO2 NPs/PDMS composite films with moderate thicknesses showed a maximum output voltage of 51.4 V when the capping layer thickness was approximately 3 μm and the base film thickness was approximately 0.25 mm. Moreover, we obtained that the inverse of the output voltage is linearly proportional to the thicknesses of the capping layer and the base film.
REACTIVATION OF TUBERCULOSIS COEXISTING WITH SMALL CELL CARCINOMA
Authors: Bhalla Kristel , Kishan Karahyla Jai , Nehra Tushar , Yadav Ajit , Singhal Sameer , Biswa Spandan
Published: September 2023

Lung cancer is the leading cause of cancer related deaths and Tuberculosis is the leading infectious killer. The association between the two has been
studied previously. The most common association has been found with squamous cell carcinoma followed by adenocarcinoma . The chances of this
association were also found to increase in cases of reactivation of tuberculosis compared to new cases. However, only a few studies have reported
the association between tuberculosis and small cell carcinoma in the past. We hereby report a case of small cell carcinoma, diagnosed in a patient
with reactivation of pulmonary tuberculosis based on clinical and radiological suspicion and conrmed by histopathology. However, whether the
carcinoma arose from the residual TB lesion could not be ascertained. Because of rare association of small cell carcinoma with tuberculosis
especially in a treated patient of tuberculosis we report this case. It should prompt the clinicians to have a high degree of suspicion to rule out
alternative or coexisting diagnosis in treated cases of tuberculosis and to not merely limit themselves to a single diagnosis for optimal patient care.
MASSIVE PLEURAL EFFUSIONS IN CANCER PATIENTS: AN EXPERIENCE FROM A TERTIARY CARE CENTRE IN INDIA
Authors: R Nair Gayathri , Kumar E Senthil , K Sivasubramaniam , G D Gangadharan S
Published: September 2023

Introduction
Massive pleural effusions are typically characterised by collection of 1000 ml or more uid in the pleural cavity. It may be a malignant or a nonmalignant effusion and is common in cancer patients.
Aims and objectives
1. To study the clinical prole of cancer patients who develop massive pleural effusions.
2. To analyse the management of massive pleural effusions in cancer patients.
Materials and methods
This is a retrospective study. Records of cancer patients diagnosed to have massive pleural effusions from the month of April 2022-November
2022, in our department were analysed in December 2022. Data regarding the clinical prole and management of pleural effusion of these patients
was collected and analysed. Results During the study period,32 cancer patients were diagnosed to have a massive pleural effusion, out of which 24
had a malignant pleural effusion. The most common cause of malignant pleural effusion was lung cancer (38%), followed by breast cancer (29%).
Therapeutic thoracocentesis alone was done for 14 patients. Therapeutic tapping was followed by Intercostal Chest Drain (ICD) insertion for 12
patients, whereas 6 patients had an upfront ICD inserted. Elderly age, ICD insertion and the development of hospital acquired pneumonia(HAP)
were associated with signicantly longer duration of hospital stay. ICD insertion was signicantly associated with the development of HAP . No
signicant difference was observed in the recurrence rate between patients who underwent ICD insertion vs therapeutic thoracocentesis alone.
Conclusions Upfront ICD insertion for management of massive pleural effusions in cancer patients is associated with increased rates of HAP,
prolonged duration of hospital stay and no difference in the rate of recurrence of effusions, when compared to patients who underwent therapeutic
thoracocentesis alone. Thus, we suggest that these patients undergo therapeutic needle thoracocentesis as the rst line of management, with an
attempt to avoid ICD insertion if possible.
Maximum-likelihood detection with QAOA for massive MIMO and Sherrington-Kirkpatrick model with local field at infinite size
Authors: Gulbahar Burhan
Published: September 2023

Quantum-approximate optimization algorithm (QAOA) is promising   in  Noisy Intermediate-Scale Quantum (NISQ) computers with applications for  NP-hard combinatorial optimization problems. It is recently utilized for NP-hard maximum-likelihood (ML) detection problem with fundamental challenges of optimization, simulation and performance analysis for  n x n multiple-input multiple output (MIMO) systems with large n. QAOA is recently applied  by Farhi et al. on infinite size limit  of Sherrington-Kirkpatrick (SK) model with a cost model including only quadratic terms.   In this article, we extend application of QAOA on SK model by including also linear terms  and then realize SK modeling of massive MIMO ML detection by ensuring independence from specific problem instance and size  n while preserving computational complexity of O(16p) designed by Farhi et al. We provide both optimized and extrapolated angles for p in the set [1, 14] and signal-to-noise (SNR) < 12  dB achieving near-optimum ML performance for 25 x 25 MIMO system with p >= 4  in extensive simulations where  236500 different QAOA circuits are simulated.  We present two conjectures about the concentration properties of QAOA  and  its near-optimum performance for massive MIMO systems with large sizes covering n  < 300 promising significant performance for next generation massive MIMO systems.
A menekülés mint életprogram Sándor Iván újabb műveiben
Authors: Novák Anikó
Published: September 2023

Míg a kortárs magyar irodalomban marginális témának számít az elmúlt évek európai menekültválsága, Sándor Iván két regénye is reflektál rá, A hetedik nap (2018) és az Amit a szél susog (2020). A két mű időben és térben is távol áll egymástól, de a két narratíva egymást kiegészítve árnyalt képet fest a menekülés módozatairól, kultúrtörténetéről, illetve az egyén életében betöltött szerepéről. A korábbi regény bár egyéni sorsokat is felvázol, a hatalmas tömegek állandó hömpölygésével teremti meg az ábrázolt korszak vészterhes, reménytelen atmoszféráját. A későbbi kötet az általános szorongatott léthelyzet helyett az egyéni meneküléstörténetekre helyezi inkább a hangsúlyt. Nemcsak a menekülés motívuma közös e művekben, több szállal is kapcsolódnak egymáshoz Jelen tanulmány a menekülés motívumát, annak rétegzettségét vizsgálja a két regényben, azt kívánja bemutatni, miképpen válik a könyvek lapjain a menekülés életprogrammá.
„Az igazat mondd, ne csak a valódit…”! Csángó sorskérdések Iancu Laura értelmezésében
Authors: Halász Péter
Published: September 2023

Iancu Laura a moldvai Magyarfaluban (Arini) született, teológiai, néprajztudományi diplomával, doktorátussal rendelkező kutató. Új könyvének fontos kérdése, hogy a moldvai magyar közösségre vonatkoztatva mióta és mi célból használja a tudományos élet és a közbeszéd egy része a többségtől elszakadt értelmű, pejoratív felhangú csángó szót? Az okok vizsgálata során áttekinti a Kárpát-medencéből a 13. századtól folyamatosan érkező magyar csoportok történelmét, katolikus vallásuk és anyanyelvük megtartásának nehézségeit, néprajzi jegyeiket, valamint az identitásukat veszélyeztető körülményeket.
Motol Blues
Authors: Giżycki Marcin
Published: September 2023

Sławna w latach 50. i 60. chicagowska wytwórnia płytowa Chess Records wylansowała wielu afroamerykańskich artystów, a także dokonała pierwszych w USA nagrań Rolling Stonesów. Została założona przez braci Leonarda i Phila Chessów (urodzonych jako Lejzor i Fiszel Czyż), emigrantów z miejscowości Motol na Polesiu, którzy przybyli do Chicago w 1928 r. Osiemdziesiąt lat później powstały na temat tej wytwórni i jej założyciela, Leonarda, dwa filmy fabularne: Cadillac Records (reż. Darnell Martin) oraz Who Do You Love (reż. Jerry Zaks). Tekst Giżyckiego skupia się na pierwszym z tych dzieł, które opowiada o fascynacji żydowskiego emigranta z małego sztetlu na rubieżach Polski muzyką czarnych imigrantów z południa Stanów Zjednoczonych. Przy okazji autor prostuje kilka mitów, pokutujących w polskich publikacjach na temat braci Czyż.
Film jako zdarzenie
Authors: Gwóźdź Andrzej
Published: September 2023

Monografia Topografie i krajobrazy. Filmowy Śląsk (2017) Ilony Copik oferuje czytelnikowi całościowe ujęcie kwestii „filmowego Śląska” w perspektywie geografii kulturowej regionu. Za przedmiot rozważań autorka obiera filmy „topograficzne”, czyli takie, w których przedstawione na ekranie miejsce jest wypadkową świadomych działań twórczych i ewokuje określoną strategię dotyczącą przestrzeni w rozmaitych kontekstach. Książa Copik przedstawia satysfakcjonujący, bo całościowy, oryginalny i inspirujący, a niejednokrotnie poznawczo wyrafinowany obraz filmowego Śląska. Ukazując żywotność praktyk filmowych związanych z górnośląskimi reprezentacjami ekranowymi, z całą mocą uświadamia, że zajmowanie się kinem śląskim oznacza dotykanie newralgicznych dla wiedzy o kulturze kwestii, podobnie jak zastosowany w pracy splot metod i narzędzi badawczych fortunnie służy rozpoznaniom filmowych topografii i krajobrazów.
Implementation of Learning with the Problem Posing Method to Increase Activeness and Learning Outcomes of Physics in the Material of Temperature and Heat
Authors: Purnomo M. , Aimran Wan Mohm , Prasitpong Singha
Published: September 2023

Purpose of the study: This research aims to find out how physics learning using the Problem posing Method is implemented in high school and to find out whether learning physics using the Problem posing Method can increase the activeness and learning outcomes of high school students in physics. Methodology: This type of research is classroom action research carried out in 2 cycles. This research was conducted in high school. The subjects of this research were 31 students of class X high school. The research data is in the form of student activity and learning outcomes. Students' learning activity is known from the results of observation sheets, while students' learning outcomes are known from the results of evaluations carried out at the end of each cycle. Main Findings: The results showed that the active learning of students in cycle II showed an increase when compared to cycle I. The results showed learning with the Problem Posing model was preferred by students so that it was hoped that the teacher could apply the Problem Posing model as a variation in learning Physics. The limitation of the research which only applies the Problem Posing model to the material Temperature and Heat with a relatively short research time, it is hoped that further research can be carried out on other materials. Novelty/Originality of this study: The novelty of this research is that classroom action research was carried out to determine students' activeness in the learning process using a problem posing model specifically for learning physics on temperature and heat.
THE MAIN TRENDS IN THE EMERGENCE AND STAGES OF DEVELOPMENTOF THE NETWORK OF SPECIAL EDUCATIONAL INSTITUTIONS OF THE BASHKIR ASSR
Authors:   Akmulla Bashkir State Pedagogical University, Kilmetova Guzel Z.
Published: September 2023

Education and upbringing of children with developmental disabilities is one of the most pressing issues of modern society. This paper discusses the trends in the development of special education in the Republic of Bashkortostan throughout the entire Soviet period. The author identifies the stages of development, proving their historiographic validity.
ADVANTAGES AND DISADVANTAGES OF ONLINE LEARNING
Authors:   North Caucasian State Academy, Napso Marianna D.
Published: September 2023

The article reveals some features of online learning, examines its advantages and disadvantages, traces its relevance to the modern education system, largely based on digital technologies. Attention is drawn to the innovative nature of this educational model. The nature of synchronous and asynchronous learning formats is investigated, the need for a rational combination of mixed (hybrid) and traditional educational practices in the educational process is emphasized, including from the point of view of increasing cooperation between educational institutions and the real sector of the economy. The role of online learning in the formation of scientific and educational competencies and practical skills is shown.
VERBAL CREATIVITY ATTRIBUTES OF MODERN STUDENTS
Authors:   Belgorod State National Research University, Shvetsova Vitalina A. , Kuznetsova Lyudmila B. ,   Belgorod State National Research University, Sharapov Alexey O. ,   Belgorod State National Research University
Published: September 2023

Verbal creativity is an important psychological condition for developing creative aspects of professional competence in students. The empirical study revealed insufficient level of verbal creativity development with regard to the criteria of authenticity and originality. The analysis of association content allowed to reveal psychological resources for the development of verbal creative thinking.
A PRAGMÁTICA DA LINGUAGEM E O MOVIMENTO DE OCUPAÇÃO DAS ESCOLAS PÚBLICAS ESTADUAIS DO SUDESTE
BRASILEIRO
Authors: Zotarelli Mauricio
Published: September 2023

Este trabalho tem por objetivo analisar a atuação dos alunos secundaristas da rede públicaestadual da Região Sudeste brasileira na ocupação das escolas sob a ótica dos estudos dapragmática da linguagem. Para isso, a pesquisa busca expor a situação imposta pelo poderpúblico enfrentada pelos alunos, sua organização no movimento para a coesão do grupo etomada de decisões, os meios utilizados para a difusão de informações e auxílio a alunos denovas ocupações, e o diálogo com população e comunidade no entorno.