bluuebunny/crossref_metadata_2025 huggingface dataset:
Research at a Distance: Replicating Semantic Differentiation Effects Using Remote Data Collection With Children Participants
Authors: Vales Catarina , Wu Christine , Torrance Jennifer , Shannon Heather , States Sarah L. , Fisher Anna V.
Published: August 2021

Remote data collection procedures can strengthen developmental science by addressing current limitations to in-person data collection and helping recruit more diverse and larger samples of participants. Thus, remote data collection opens an opportunity for more equitable and more replicable developmental science. However, it remains an open question whether remote data collection procedures with children participants produce results comparable to those obtained using in-person data collection. This knowledge is critical to integrate results across studies using different data collection procedures. We developed novel web-based versions of two tasks that have been used in prior work with 4-6-year-old children and recruited children who were participating in a virtual enrichment program. We report the first successful remote replication of two key experimental effects that speak to the emergence of structured semantic representations (N = 52) and their role in inferential reasoning (N = 40). We discuss the implications of these findings for using remote data collection with children participants, for maintaining research collaborations with community settings, and for strengthening methodological practices in developmental science.
Benefits of Integrating an Explicit Self-Efficacy Intervention With Calculation Strategy Training for Low-Performing Elementary Students
Authors: Koponen Tuire , Aro Tuija , Peura Pilvi , Leskinen Markku , Viholainen Helena , Aro Mikko
Published: August 2021

This study examined the malleability of math self-efficacy (SE) among children with poor calculation fluency via an intervention that targeted four sources of SE (mastery experiences, vicarious experiences, social persuasions, and emotional and physiological states). The effect of pure strategy training was contrasted with an intervention that integrated strategy training and explicit SE support. Moreover, the changes in SE source experiences and their relation with math SE, as well as the relation between math-SE profiles and calculation fluency development, were examined. In a quasi-experimental design, 60 Finnish children with calculation fluency problems in Grades 2 to 4 participated in strategy training (N = 38) or in an intervention that integrated SE support with strategy training (N = 32) for 12 weeks. The results showed that the explicit SE intervention integrated with strategy training enhanced math SE among children with poor calculation fluency and low SE (effect size, r = 0.61). Changes in mastery experiences and social persuasions were positively associated with changes in math SE among children who received the explicit SE intervention. An initially high math-SE profile and a profile indicating an increase from low to high math SE were related to growth in calculation fluency that approached the children's average age level during the interventions. In conclusion, an integrated approach that combined skill training and SE intervention was especially beneficial for children with poor calculation fluency and low math SE.
Understanding the Mechanism of Social Attachment Role in Social Media: A Qualitative Analysis
Authors: Yang MaoSheng , Zhang WenSong , Ruangkanjanases Athapol , Zhang Yue
Published: August 2021

Qualitative research method was used to explore the formation and development of the attachment relationship between users and social media in the process of using social media. Based on the attachment theory, this study selected three representative social media platforms, namely, TikTok, WeChat, and MicroBlog, as theoretical samples, and this study adopted NVivo12.0 to root, theorize, and construct the original data. Research shows that users are stimulated by co-creation value to stimulate changes in their psychological needs and self-expression, leading to the formation of social attachment. Among them, user participation is a prerequisite for driving the occurrence of co-creation value, creating a continuous-use scenario for the attachment relationship between individuals and social media. Further, psychological needs and self-expression play mediating roles between co-creation of value and social attachment and promote the occurrence of personal belonging to software platforms. The findings of this research better our understandings about the mechanism of developing social attachment from continuous use of social media and offer practical implications for commercial uses of social media platforms.
Depression-, Anxiety-, and Anger and Cognitive Functions: Findings From a Longitudinal Prospective Study
Authors: Lindert Jutta , Paul Kimberley C. , Lachman Margie E. , Ritz Beate , Seeman Teresa E.
Published: August 2021

Background: Determinants of changes in cognitive function during aging are not well-understood. We aimed to estimate the effects of depression-, anxiety- and anger symptoms on cognition and on cognition changes, especially on changes in episodic memory (EM) and executive functioning (EF).

Methods: We analyze data from the Mid-Life in the Midlife in the United States Biomarker study at two time points including n = 710 women, and n = 542 men (1996/1997) at the first assessment and n = 669 women, and n = 514 men at the second assessment (2013/2014). To assess cognition we used the Brief Test of Adult Cognition (BTACT). To measure depression-, anxiety- and anger symptoms we used the Mood and Anxiety Symptom Questionnaire (MASQ), the Center for Epidemiologic Studies Depression Scale (CES-D) and the State-Trait Anger Expression Inventory (STAXI). We used repeated models analyses to explore changes in cognition, and repeated measures linear mixed-effects models to investigate depression, anxiety and anger effects on cognition. All analyses were adjusted for potential confounders (cognition at baseline, age, education, income).

Results: At the first assessment, women had significantly better episodic memory functioning than men; men in the oldest age group had significant better executive functioning. At the second assessment, more education, and white ethnicity were associated with less negative changes on episodic memory and executive functioning. Depression- and anger symptoms were associated with declines in episodic memory among women; anxiety symptoms were associated with declines in episodic memory and executive functioning in both gender in men (EF: β: −0.02, (95% CI: −0.03, −0.01; EM: β −0.02 (−0.02, 95% CI: −0.03, −0.01) and in women (EF: β −0.01, 95% CI: −0.02, −0.0004; EM: β −0.013, 95% CI: −0.03, −0.001).

Conclusions: Depression-, anxiety- and anger symptoms were associated with changes in episodic memory and executive functioning. Further longitudinal studies are critical in populations in more countries to better understand the impact of depression, anxiety and anger symptoms on cognition changes.
Environmental Regulation, Promotion Pressure of Officials, and Enterprise Environmental Protection Investment
Authors: Chang Ke-Chiun , Wang Di , Lu Yangyang , Chang Wen , Ren Guangqian , Liu Li , Zhou Xueya
Published: August 2021

This study expands on the impact of local government environmental regulation on enterprise environmental protection investment. Furthermore, it analyzes the influence promotion pressure of officials has on the scale of enterprise environmental investment. The results show that the environmental protection investment of companies in China is generally insufficient. The attitude of companies toward environmental protection is passive under the policy regulation. The environmental supervision of the government is also still at a low level. Both of these observations are far from the intentions of the government. There is a U-shaped relationship between the pressure of official promotion and the scale of enterprise environmental protection investment. Only when the pressure of official promotion exceeds a certain limit can it positively stimulate enterprises to invest in environmental protection. Environmental regulation also exerts a threshold effect on the environmental protection investment by enterprises. This research provides a new way to understand the decision-making behavior of local officials and the environmental protection responsibility of enterprises. This study provides recommendations for improving the environment appraisal and government supervision system in China.
Investigating Energy Justice in Demand-Side Low-Carbon Innovations in Ontario
Authors: Wyse Susan Morrissey , Das Runa R. , Hoicka Christina E. , Zhao Yuxu , McMaster Maria-Louise
Published: August 2021

The diffusion of low-carbon innovations, including innovative products and services, is required to accelerate a low-carbon energy transition. These innovations also have the potential to alleviate and perpetuate existing social inequities, calling into question their “justness.” Energy justice is a useful analytical tool for framing justice questions related to energy. In this paper, we ask whether demand-side low-carbon energy innovations are meeting energy justice criteria. To address this question, this study develops four indicators from existing energy justice frameworks and applies them to a range of demand-side innovations offered to energy users in Ontario. The indicators are used to assess innovation availability, affordability, information, and involvement. Innovations were identified using surveys and desk research across Ontario's energy technology innovation system (ETIS). One hundred twenty-two innovations are analyzed for these four indicators, and according to intended innovation users and innovation providers. Findings suggest that three of the four indicators—availability, affordability and information are broadly being addressed, while involvement was more difficult to establish. However, the ETIS may be perpetuating inequities through an over emphasis of innovations for particular energy users, such as private businesses, alongside under-emphasis on potentially marginalized actors, such as low-income households and renters. Furthermore, government-delivered, publicly owned or regulated innovation providers place a greater emphasis on energy justice, including the provision of innovations for marginalized actors. This study aids our understanding of energy justice in low-carbon energy innovations and is critical given that in the context of funding cuts to public services, there may be an increased reliance on decentralized actors. The consideration of justice gaps that emerge through such decentralization should not be overlooked. Our findings suggest that within Ontario's ETIS, who provides innovations matters. Given the insights presented in this study, this research approach and the developed indicators could be applied to other contexts and socio-technical systems. The application of energy justice indicators, derived from existing scholarship, therefore presents an important opportunity to address current and understudied practical energy challenges.
Climate Change, Flood Disaster Risk and Food Security Nexus in Northern Ghana
Authors: Atanga Raphael Ane , Tankpa Vitus
Published: August 2021

This research reviews climate change, flood disasters impacts and food security nexus in northern Ghana. The impacts of climate change include flood disasters which in turn affect food production with subsequent impact on food security. While climate change impact can be positive in some regions, it can be negative in other regions as it could lead to excess or lack of water, which negatively affects food production. Most especially, flood disasters have reportedly become frequent with devastating consequences on food production. Literature further suggests that the frequency of floods and their impacts have the potential to increase in the future. Floods inundate farms, pastures and livestock, which could subsequently reduce crop yields and animal production. Floods also destroys physical infrastructure and disrupts socio-economic activities which are linked to agriculture sector and could affect food production. This eventually decreases food availability, accessibility, utilization, and stability in the region. Northern Ghana has experienced flood disasters with increased frequency, which are related to climate change impacts. Although there is research on climate change, flood disasters, and food security issues in northern Ghana, the literature thus far indicates no clear focus of studies that focuses on the nexus of climate change, flood disasters, and food security of the study site. Thus, this research seeks to review the nexus of climate change, and flood disaster impacts on food security in northern Ghana with their implications on food security in the region. This study has two main research objectives. The first objective of this research is to identify and understand the potential impacts of climate change and flood disasters on food production in the study site. The second research objective is to explain the connection between climate change and flood disasters and the implications of this relationship on food security in the study site. This review study focuses on climate change, flood disasters, and food production to understand the critical impacts of climate change and flood disasters on food security in the northern part of Ghana. The aim of this research is to contribute to literature and discussion of the nexus of climate change, flood disaster impacts and food security sub-Saharan Africa.
U.S. Cattle Producer Adoption of Secure Beef Supply Plan Enhanced Biosecurity Practices and Foot-and-Mouth Disease Preparedness
Authors: Pudenz Christopher C. , Mitchell James L. , Schulz Lee L. , Tonsor Glynn T.
Published: August 2021

The prospect of a foot-and-mouth disease (FMD) outbreak in U.S. livestock populations has motivated the development of the Secure Beef Supply (SBS) Plan, which includes a comprehensive list of enhanced biosecurity practices that aim to prevent FMD transmission and facilitate continuity of business during an outbreak. While FMD poses a serious threat to livestock production in the United States, little is known about producers' uptake of the enhanced biosecurity practices included in the SBS Plan. In this study, we benchmark adoption and feasibility-of-adoption perceptions for U.S. cattle producers. Our results show adoption of the 13 enhanced biosecurity practices is generally low. Especially concerning is the low adoption of the three strongly-recommended pre-outbreak practices—having a biosecurity manager, having a written operation-specific enhanced biosecurity plan, and having a line of separation. Adoption of the pre-outbreak practices is likely low because the benefits of adopting the practices depend on a low probability, uncertain event. That said, producers who have adopted the pre-outbreak practices are more likely to have higher feasibility ratings for the remaining enhanced biosecurity practices, suggesting that adoption of the strongly recommended practices is associated with adoption of all enhanced biosecurity during an FMD outbreak. Complementarity is examined and shows that adoption of the pre-outbreak practices coincides with adoption of the outbreak-specific practices. Taken together, our results suggest that adoption of the strongly recommended pre-outbreak practices could help facilitate a quicker and more effective U.S. cattle industry response to an FMD outbreak in the United States.
Comparative Trial of Continuous Flow Enteral and Intravenous Fluid Therapy in Horses
Authors: Dias Domingos C. R. , Ribeiro Filho José D. , Viana Rinaldo B. , Bittencourt Thereza C. C. , Dantas Fernanda T. D. R. , Teixeira Raffaella B. C. , Di Filippo Paula A. , Manso Filho Hélio C. , Alves Samuel R. , Santos Paulo V. M. , Moreira Nadyne S.
Published: August 2021

Continuous flow enteral fluid therapy with isotonic and hypotonic enteral electrolyte solutions are as safe and effective as intravenous fluid therapy. The aim of this study was to carry out a comparative assessment between continuous flow enteral and intravenous (IV) fluid therapy in adult experimentally dehydrated horses. Six experimentally dehydrated adult mares were used in a study carried out in a 6 × 3 crossover design, which each animal received three different treatments (isotonic enteral fluid therapy—EsISO, hypotonic enteral fluid therapy—EsHYPO and intravenous fluid therapy with Lactate Ringer Solution—LR IV, all in continuous flow). Solutions were administered at a rate of 15 mL−1.kg−1.h−1 for 8 h, after 36 h of water and food deprivation. Serum and urinary biochemical assessment; urinary volume, pH and specific gravity; and blood gas analysis were measured at −36, 0, 2, 4, 6, and 8 h. The dehydration period (DP) caused discrete hydroelectrolytic and acid base imbalances. The EsISO, EsHYPO and LR IV increased blood volume. Enteral solutions restored the imbalances yielded by the DP and all treatments increased urine volume. Also, the EsHYPO and LR IV showed no effects in acid base balance, while EsISO showed slightly acidifying effect. The present study certifies the efficacy and safety of isotonic and hypotonic continuous flow enteral fluid therapy in comparison to IV fluid therapy in dehydrated horses.
HRM Policies’ Impact on Employees’ Employability: The Role of Age Climate and the Offering of Developmental Measures
Authors: Schrimpf Marlene , Froehlich Dominik Emanuel , Covarrubias Venegas Barbara
Published: August 2021

How can (aging) individual employees continue to grow as persons, on the one hand, and contribute to their employing organizations in meaningful ways, on the other hand? In this article, we set out to study how two important instruments of human resource management—age climate and the offering of developmental measures—may help. We use path modeling to investigate the research model based on data of 208 respondents of both rural and urban regions in Austria. The results indicate that a positive organizational age climate has a positive influence on the offering of developmental measures and, subsequently, on employees’ employability. We emphasize the importance of facilitating developmental measures for staff of all ages, as well as the necessity to address the organizational age climate to successfully tackle the challenges of demographic change.
Thermal Analysis and Testing of Different Designs of LaB6 Hollow Cathodes to Be Used in Electric Propulsion Applications
Authors: Kokal Ugur , Turan Nazli , Celik Murat
Published: August 2021

LaB6 emitters are commonly used in hollow cathodes that are utilized in electric space propulsion systems. In order to obtain necessary surface current emission densities of 1–10 A/cm2 for cathode operations, LaB6 emitters require temperatures above 1500 °C. Hence, the design for LaB6 cathodes presents thermal and mechanical challenges. In this paper, several design iterations for LaB6 hollow cathodes are presented and thermal analyses are conducted for each design. Temperature and heat flux distributions that are obtained from thermal analyses are investigated. The designs are evaluated according to the required heat input to the emitter, and the radiative and conductive heat loss mechanisms. In addition to the thermal analyses, experimental tests are conducted for different cathode designs and, based on these tests, various modes of failure are determined. Revising the cathode design and the material selection iteratively to eliminate the encountered failure mechanisms, a novel cathode design is achieved. Experimental tests of this novel cathode are conducted and current-voltage characteristics are presented for different mass flow rates and for discharge currents between 0.5 and 12 A. Tests and analysis results show that the selection of materials and design are crucial for a sturdy and long lifetime cathode.
Effects of Dietary Supplementation of Humic Substances on Production Parameters, Immune Status and Gut Microbiota of Laying Hens
Authors: Mudroňová Dagmar , Karaffová Viera , Semjon Boris , Naď Pavel , Koščová Jana , Bartkovský Martin , Makiš Andrej , Bujňák Lukáš , Nagy Jozef , Mojžišová Jana , Marcinčák Slavomír
Published: August 2021

Despite the fact that humic substances (HS) have been frequently studied in relation to their effects on livestock health, studies on their influence on egg production and quality, immunity, and intestinal microbiota of laying hens are limited. In this study, the influence of 0.5% HS supplementation on the specific production parameters of eggshell mineral quality, immune parameters (relative expression of IgA, IGF-2, MUC-2 gene in cecum; activity of phagocytes, percentage of selected lymphocyte subpopulations in the peripheral blood), and number of lactic acid bacteria and enterobacteria in the intestinal contents in laying hens was tested. The addition of 0.5% HS to the laying hen feed had a positive effect on egg laying rate, daily egg mass, egg weight, feed conversion and eggshell quality and also had an immunostimulatory effect manifested by increased phagocyte activity and B cell response. Concurrently, an increase in the number of enterobacteria in the intestinal contents and a decrease in the proportion of T lymphocytes (p < 0.05) was observed, which can be considered as a negative effect of HS. The results confirmed that HS can be used for the improvement of egg production and targeted immunostimulation, but their effect on the intestinal microbiota and T lymphocytes should be studied in more detail.
Evaluation of the Effectiveness of Spirotetramat on the Diaspine Scale Parlatoria pergandii in Citrus Orchards
Authors: Assouguem Amine , Kara Mohammed , Mansouri Ismail , Imtara Hamada , AlZain Mashail N. , Mechchate Hamza , Conte Raffaele , Squalli Wafae , Farah Abdellah , Lazraq Abderrahim
Published: August 2021

The control of Parlatoria pergandii (Comstock, 1881) was studied in citrus orchards at Belksiri (Gharb area), Morocco. Three concentrations of Spirotetramat (T0 = 0 L/Ha, T1 = 0.625 L/Ha, T2 = 0.755 L/Ha, and T3 = 1 L/Ha) were applied to 4 ha of Valencia late orchard (each dose for 1 ha of citrus). The insecticidal of Spirotetramat was evaluated on two stages of larvae (L1 and L2) of P. pergandii and three stages of females, F1, F2, and F3. Similarly, the rates of parasitism by Aphytis hispanicus on the females of three different stages were monitored to evaluate the impact of Spirotetramat on this natural enemy. Results showed that Spirotetramat was more effective on larvae than females. Of the females, 26.04% were parasitized, 65.81% were inhibited, and only 8.15% were intact after the treatment period. Of the larvae, 79.73% were inhibited, and only 20.27% survived after the treatment period. Finally, our study highlights that all the tested concentrations of this product were effective on the population of P. pergandii. On the other hand, this product showed a less negative impact on the parasitized females with the low concentration (0.625 L/Ha) compared to the high concentrations of the pesticide (T2 = 0.755 L/Ha and T3 = 1 L/Ha), especially for the female stages F2 and F3. Moreover, the impact on the water table will be less severe with a low concentration.
Compost Fungi Allow for Effective Dispersal of Putative PGP Bacteria
Authors: González-González Susett , Astorga-Eló Marcia , Campos Marco , Wick Lukas Y. , Acuña Jacquelinne J. , Jorquera Milko A.
Published: August 2021

Use of compost is a common agricultural practice. It improves soil fertility by adding nutrients and plant growth promoting (PGP) microorganisms. The role of bacterial-fungal interactions for compost-driven fertilization, however, is still poorly understood. In this study, we investigated whether putative PGP bacteria associate to and disperse along mycelia of fungal isolates. A ‘Fungal highway column system’ was used to isolate and characterize fungal—bacterial couples derived from commercial compost (C), non-composted bulk soil (BS) and rhizosphere soil with compost application (RSC). Bacterial-fungal couples were identified by 16S and 18S rRNA gene sequencing and isolated bacteria were tested for representative PGP traits. Couples of fungi and associated migrator bacteria were isolated from C and RSC only. They included the fungal genera Aspergillus, Mucor, Ulocladium, Rhizopus and Syncephalastrum, and the bacterial genera Rhodococcus, Bacillus, Pseudomonas, Agrobacterium, Glutamicibacter and Microbacterium. Many of migrator bacteria in RSC and C showed PGP traits (e.g., tryptophane—induced auxin synthesis or phytate mineralizing activity) suggesting that fungi contained in C and RSC allow for dispersal of putative PGP bacteria. Next to being provider of nutrients, compost may therefore be source for PGP bacteria and fungal mycelia serving as networks for their efficient dispersal.
Integrated-Smart Agriculture: Contexts and Assumptions for a Broader Concept
Authors: Martinho Vítor João Pereira Domingues , Guiné Raquel de Pinho Ferreira
Published: August 2021

The innovative technologies developed in the different fields of science (nanotechnology, artificial intelligence, genetic modification, etc.) opened new and infinite possibilities for the several stakeholders that carry out their activities in the different economic sectors. For agriculture, these new approaches are particularly relevant and may bring interesting contributions, considering the specificities of the sector, often dealing with contexts of land abandonment and narrow profit margins. Nonetheless, the question in these unstopped evolutions is about the interlinkages with sustainability. In this context, the objectives of this study are to highlight the main insights from the available scientific literature about the interrelationships between the new trends in the agriculture and the sustainability. To achieve these aims, a search on the Web of Science Core Collection (WoS) and Scopus databases was carried out, on 15 May 2021, for the topics ‘smart agriculture’ and ‘sustainability’. A total of 231 documents (102 from WoS and 129 from Scopus) were obtained, remaining 155 documents after removing the duplicated, which were surveyed through systematic review following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) approach. As main insights, the concerns of the researchers with the impacts on the sustainability from the transformations in the farming organization are highlighted. On the other hand, it was shown the relevance and the new opportunities, including in terms of food supply, arising from the precision agriculture, agricultural intelligence, vertical/urban farming, circular economy, internet of things, and crowdfarming. We suggest the new and wider concept of ‘integrated-smart agriculture’, better than ‘climate-smart agriculture’.
Comprehensive Evaluation of Salt Tolerance in Rice (Oryza sativa L.) Germplasm at the Germination Stage
Authors: Zhang Rui , Hussain Shahid , Wang Yang , Liu Yonghao , Li Qing , Chen Yinglong , Wei Huanhe , Gao Pinglei , Dai Qigen
Published: August 2021

Salt stress reduces the yield and quality of rice. It is of great significance to screen out salt-tolerant varieties for the development and utilization of saline land. The study was carried out on 114 rice varieties; first, seven varieties were selected and treated with different salt concentrations (0, 50, 85, 120, 155, 190, 225 mM), and seven traits, including germination energy, germination capacity, shoot length, root length, root number, plant fresh weight, and seedling vigor index, were measured. The salt concentration at which the sodium chloride injury index was 50% of the control was considered the optimal salt concentration. Second, 114 rice germplasms were carried out under an optimal salt concentration (120 mM). Then, principal component analysis, fuzzy function analysis, stepwise regression analysis, correlation analysis, and systematic cluster analysis were carried out on each parameter. There was a significant correlation between each parameter and the D-value, and the correlation coefficient between the seedling vigor index and D-value was the highest. D-value = − 0.272 + 1.335 × STI − SVI + 0.549 × STI − RN − 0.617 × STI-RL + 0.073 × STI − GE, R2 = 0.986. Using this equation, the sodium chloride tolerance of rice in the germination experiment could be quickly identified. This study showed that the seedling vigor index was a reliable parameter to identify the salinity tolerance of rice varieties. Five groups were obtained by classification at a Euclidean distance of 5. There were 8 highly salt-tolerant cultivars, 23 salt-tolerant cultivars, 42 cultivars with moderate salt tolerance, 33 salt-sensitive cultivars, and 8 highly salt-sensitive cultivars. In this study, we found that Riguang was the most salt-tolerant rice variety, and Xiangxuejing15 was the most salt-sensitive variety.
Antibiotics to Prevent Surgical Site Infection (SSI) in Oral Surgery: Survey among Italian Dentists
Authors: Lollobrigida Marco , Pingitore Gianluca , Lamazza Luca , Mazzucchi Giulia , Serafini Giorgio , De Biase Alberto
Published: August 2021

The benefit of an antibiotic prophylaxis for most oral surgical procedures is controversial. The aim of this study was to collect information on the prescribing habits of a sample of Italian dentists with respect to the role of antibiotic prophylaxis in preventing surgical site infections (SSI). An anonymous questionnaire was prepared and made accessible online by sharing a Google Forms link. General anagraphic data and educational background information were collected to obtain a profile of the participants. Different clinical scenarios were then proposed, with the participants asked to choose whether they would prescribe an antibiotic prophylaxis and with which dosage regimens. In total, 169 dentists participated in the questionnaire and the obtained data were assessed through a percentage report. The results showed a substantial agreement in antibiotics prescription, but only in a limited number of clinical scenarios, such as deciduous teeth extraction or simple extractions in healthy adult patients. Discordant responses were found for several clinical cases, particularly for cases of comorbidities, surgical or multiple extractions, implant placement and abscess drainage. The answers obtained from the survey sample were notably heterogeneous, indicating that the choice to prescribe an antibiotic prophylaxis to prevent SSIs is often discretionary. Moreover, the dosage regimen of prophylaxis is also controversial. The results of this study demonstrate the need for specific guidelines on antibiotics in dentistry and, specifically, on antibiotic prophylaxis in oral surgery. Such guidelines would help to avoid unnecessary prescriptions.
Intestinal and Hepatic Uptake of Dietary Peroxidized Lipids and Their Decomposition Products, and Their Subsequent Effects on Apolipoprotein A1 and Paraoxonase1
Authors: Jiang Xueting , Deme Pragney , Gupta Rajat , Litvinov Dmitry , Burge Kathryn , Parthasarathy Sampath , Narasimhulu Chandrakala Aluganti
Published: August 2021

Both pro- and antiatherosclerotic effects have been ascribed to dietary peroxidized lipids. Confusion on the role of peroxidized lipids in atherosclerotic cardiovascular disease is punctuated by a lack of understanding regarding the metabolic fate and potential physiological effects of dietary peroxidized lipids and their decomposition products. This study sought to determine the metabolic fate and physiological ramifications of 13-hydroperoxyoctadecadienoic acid (13-HPODE) and 13-HODE (13-hydroxyoctadecadienoic acid) supplementation in intestinal and hepatic cell lines, as well as any effects resulting from 13-HPODE or 13-HODE degradation products. In the presence of Caco-2 cells, 13-HPODE was rapidly reduced to 13-HODE. Upon entering the cell, 13-HODE appears to undergo decomposition, followed by esterification. Moreover, 13-HPODE undergoes autodecomposition to produce aldehydes such as 9-oxononanoic acid (9-ONA). Results indicate that 9-ONA was oxidized to azelaic acid (AzA) rapidly in cell culture media, but AzA was poorly absorbed by intestinal cells and remained detectable in cell culture media for up to 18 h. An increased apolipoprotein A1 (ApoA1) secretion was observed in Caco-2 cells in the presence of 13-HPODE, 9-ONA, and AzA, whereas such induction was not observed in HepG2 cells. However, 13-HPODE treatments suppressed paraoxonase 1 (PON1) activity, suggesting the induction of ApoA1 secretion by 13-HPODE may not represent functional high-density lipoprotein (HDL) capable of reducing oxidative stress. Alternatively, AzA induced both ApoA1 secretion and PON1 activity while suppressing ApoB secretion in differentiated Caco-2 cells but not in HepG2. These results suggest oxidation of 9-ONA to AzA might be an important phenomenon, resulting in the accumulation of potentially beneficial dietary peroxidized lipid-derived aldehydes.
Malaria Pigment Hemozoin Impairs GM-CSF Receptor Expression and Function by 4-Hydroxynonenal
Authors: Skorokhod Oleksii , Barrera Valentina , Mandili Giorgia , Costanza Federica , Valente Elena , Ulliers Daniela , Schwarzer Evelin
Published: August 2021

Malarial pigment hemozoin (HZ) generates the lipoperoxidation product 4-hydroxynonenal (4-HNE), which is known to cause dysregulation of the immune response in malaria. The inhibition of granulocyte macrophage colony-stimulating factor (GM-CSF)-dependent differentiation of dendritic cells (DC) by HZ and 4-HNE was previously described in vitro, and the GM-CSF receptor (GM-CSF R) was hypothesised to be a primary target of 4-HNE in monocytes. In this study, we show the functional impact of HZ on GM-CSF R in monocytes and monocyte-derived DC by (i) impairing GM-CSF binding by 50 ± 9% and 65 ± 14%, respectively (n = 3 for both cell types); (ii) decreasing the expression of GM-CSF R functional subunit (CD116) on monocyte’s surface by 36 ± 11% (n = 6) and in cell lysate by 58 ± 16% (n = 3); and (iii) binding of 4-HNE to distinct amino acid residues on CD116. The data suggest that defective DC differentiation in malaria is caused by GM-CSF R dysregulation and GM-CSF R modification by lipoperoxidation product 4-HNE via direct interaction with its CD116 subunit.
Evaluation of Reinforcement and Deep Learning Algorithms in Controlling Unmanned Aerial Vehicles
Authors: Jembre Yalew Zelalem , Nugroho Yuniarto Wimbo , Khan Muhammad Toaha Raza , Attique Muhammad , Paul Rajib , Shah Syed Hassan Ahmed , Kim Beomjoon
Published: August 2021

Unmanned Aerial Vehicles (UAVs) are abundantly becoming a part of society, which is a trend that is expected to grow even further. The quadrotor is one of the drone technologies that is applicable in many sectors and in both military and civilian activities, with some applications requiring autonomous flight. However, stability, path planning, and control remain significant challenges in autonomous quadrotor flights. Traditional control algorithms, such as proportional-integral-derivative (PID), have deficiencies, especially in tuning. Recently, machine learning has received great attention in flying UAVs to desired positions autonomously. In this work, we configure the quadrotor to fly autonomously by using agents (the machine learning schemes being used to fly the quadrotor autonomously) to learn about the virtual physical environment. The quadrotor will fly from an initial to a desired position. When the agent brings the quadrotor closer to the desired position, it is rewarded; otherwise, it is punished. Two reinforcement learning models, Q-learning and SARSA, and a deep learning deep Q-network network are used as agents. The simulation is conducted by integrating the robot operating system (ROS) and Gazebo, which allowed for the implementation of the learning algorithms and the physical environment, respectively. The result has shown that the Deep Q-network network with Adadelta optimizer is the best setting to fly the quadrotor from the initial to desired position.
Microbiological Contamination in Different Food Service Units Associated with Food Handling
Authors: Alves Ana , Viveiros Cristina , Lopes Jéssica , Nogueira António , Pires Bruno , Afonso Andrea F. , Teixeira Cristina
Published: August 2021

Background: A microbiological analysis of samples taken from hands of food handlers and utensils/crockery in food service units was used to assess the risk of food contamination. We aimed to assess indicators of microbiological contamination in different food service units. Methods: We used data for an official inspection proposal (2018–2019) in different food service units serving a district in Northeast Portugal. We showed the proportion of positive samples for each microorganism assessed in samples taken from hands and kitchen utensils/crockery. Results: Out of 471 samples taken from hands of food handlers, 26.8% (n = 126) were classified as “unsatisfactory” due to the presence of at least Escherichia coli, Staphylococcus aureus and/or total and fecal coliforms. Such a proportion varied according to the type of food service unit with a higher proportion being observed in Canteens (40.0%) and in Retirement Home/Day Care Centers (37.8%). More than one third of 649 samples taken from kitchen utensils/crockery were classified as “unsatisfactory” (n = 181; 27.9%) or “bad” (n = 49; 7.6%). There were significant differences in these proportions across food service units, with a higher proportion of “unsatisfactory” samples being observed in Fishmongers and Butcher Shops/Charcuteries (50.0% and 45.1%, respectively), while a higher proportion of “bad” samples was observed in both Pastry/Bakery and Fishmonger establishments (33.3%), followed by Butcher Shops/Charcuteries (14.1%). Conclusions: Our results emphasize the need of awareness of hygiene practices among food handlers of different food service units, particularly in Fishmongers, Pastry/Bakery establishments and Butcher Shops/Charcuteries, highlighting the need of a periodic hygienic evaluation.
The Role of RANKL and Involvement of Cementum in Orthodontic Root Resorption
Authors: Yamaguchi Masaru , Mishima Hiroyuki
Published: August 2021

Orthodontic root resorption (ORR) is an unintended side effect of orthodontic treatment, and severe ORR can affect treatment outcome. Receptor activator of nuclear factor kappa-B ligand (RANKL) has been detected in the resorbed cementum and periodontal (PDL) tissues exposed to excessive orthodontic forces. Recent studies have demonstrated that PDL cells and cementoblasts express RANKL that may play a role in ORR during orthodontic tooth movement. It is known that the hardness of cementum in human maxillary premolars differs among individuals. Furthermore, this difference has been reported to be attributed to differences in the calcium (Ca)/phosphorus (P) ratio. A correlation was observed between the Vickers hardness and Ca/P ratio of the cementum in the apical region. These findings suggest that cementum hardness and the Ca/P ratio may be indirectly involved in ORR caused by orthodontic forces. In this review, it aims to identify the role of RANKL and involvement of cementum in ORR.
Empirical Study of Test Case and Test Framework Presence in Public Projects on GitHub
Authors: Madeja Matej , Porubän Jaroslav , Chodarev Sergej , Sulír Matúš , Gurbáľ Filip
Published: August 2021

Automated tests are often considered an indicator of project quality. In this paper, we performed a large analysis of 6.3 M public GitHub projects using Java as the primary programming language. We created an overview of tests occurrence in publicly available GitHub projects and the use of test frameworks in them. The results showed that 52% of the projects contain at least one test case. However, there is a large number of example tests that do not represent relevant production code testing. It was also found that there is only a poor correlation between the number of the word “test” in different parts of the project (e.g., file paths, file name, file content, etc.) and the number of test cases, creation date, date of the last commit, number of commits, or number of watchers. Testing framework analysis confirmed that JUnit is the most used testing framework with a 48% share. TestNG, considered the second most popular Java unit testing framework, occurred in only 3% of the projects.
The Rapid Chloride Migration Test in Assessing the Chloride Penetration Resistance of Normal and Lightweight Concrete
Authors: Pontes Jorge , Bogas José Alexandre , Real Sofia , Silva André
Published: August 2021

Chloride-induced corrosion has been one of the main causes of reinforced concrete deterioration. One of the most used methods in assessing the chloride penetration resistance of concrete is the rapid chloride migration test (RCMT). This is an expeditious and simple method but may not be representative of the chloride transport behaviour of concrete in real environment. Other methods, like immersion (IT) and wetting–drying tests (WDT), allow for a more accurate approach to reality, but are laborious and very time-consuming. This paper aims to analyse the capacity of RCMT in assessing the chloride penetration resistance of common concrete produced with different types of aggregate (normal and lightweight) and paste composition (variable type of binder and water/binder ratio). To this end, the RCMT results were compared with those obtained from the same concretes under long-term IT and WDT. A reasonable correlation between the RCMT and diffusion tests was found, when slow-reactive supplementary materials or porous lightweight aggregates surrounded by weak pastes were not considered. A poorer correlation was found when concrete was exposed under wetting–drying conditions. Nevertheless, the RCMT was able to sort concretes in different classes of chloride penetration resistance under distinct exposure conditions, regardless of the type of aggregate and water/binder ratio.
Biocompatible 3D Printed Chitosan-Based Scaffolds Containing α-Tocopherol Showing Antioxidant and Antimicrobial Activity
Authors: Bergonzi Carlo , Bianchera Annalisa , Remaggi Giulia , Ossiprandi Maria Cristina , Zimetti Francesca , Marchi Cinzia , Bernini Franco , Bettini Ruggero , Elviri Lisa
Published: August 2021

Active dressings acting on multiple fronts are requested in the field of care for chronic skin ulcers in order to ameliorate patient compliance and tissue restoration. Currently, three-dimensional polymeric hydrogels are widely investigated; however, no prototypes aiming to control oxidative stress and bacterial proliferation in the wound bed have been developed up until now. The present work describes the formulation of a novel chitosan-based printable material containing α-tocopherol at stable dosages to obtain reproducible 3D scaffolds possessing antioxidant and antimicrobial activity without the use of organic solvents. Stability assays mimicking the manufacturing process and storage conditions reveal no significant drug loss. Chemico-physical characterizations including porosity and behavior after dehydration/hydration demonstrate that the dressings are highly porous, can be dehydrated up to 80%, and can recover more than 90% of water upon 1 h of rehydration. Elasticity determined by stress/strain tests was higher than human skin and was sufficiently resistant for potential clinical manipulation. Footage of fibroblasts in in vitro cultures demonstrated the biocompatibility of the constructs over 28 days. Finally, scaffolds loaded with α-tocopherol showed dose-dependent antioxidant activity (up to 80% in less than 1 h), while antimicrobial action versus multi-drug resistant strains of Pseudomonas aeruginosa and Staphilococcus aureus was assessed by inhibition rings obtained through the Kirby–Bauer technique. The proposed hydrogels can be useful as dressings for the treatment of chronically infected wounds.
Influence of Artificial Intelligence in Civil Engineering toward Sustainable Development—A Systematic Literature Review
Authors: Manzoor Bilal , Othman Idris , Durdyev Serdar , Ismail Syuhaida , Wahab Mohammad
Published: August 2021

The widespread use of artificial intelligence (AI) in civil engineering has provided civil engineers with various benefits and opportunities, including a rich data collection, sustainable assessment, and productivity. The trend of construction is diverted toward sustainability with the aid of digital technologies. In this regard, this paper presents a systematic literature review (SLR) in order to explore the influence of AI in civil engineering toward sustainable development. In addition, SLR was carried out by using academic publications from Scopus (i.e., 3478 publications). Furthermore, screening is carried out, and eventually, 105 research publications in the field of AI were selected. Keywords were searched through Boolean operation “Artificial Intelligence” OR “Machine intelligence” OR “Machine Learning” OR “Computational intelligence” OR “Computer vision” OR “Expert systems” OR “Neural networks” AND “Civil Engineering” OR “Construction Engineering” OR “Sustainable Development” OR “Sustainability”. According to the findings, it was revealed that the trend of publications received its high intention of researchers in 2020, the most important contribution of publications on AI toward sustainability by the Automation in Construction, the United States has the major influence among all the other countries, the main features of civil engineering toward sustainability are interconnectivity, functionality, unpredictability, and individuality. This research adds to the body of knowledge in civil engineering by visualizing and comprehending trends and patterns, as well as defining major research goals, journals, and countries. In addition, a theoretical framework has been proposed in light of the results for prospective researchers and scholars.
Effect of Extreme Temperatures and Driving Conditions on Gaseous Pollutants of a Euro 6d-Temp Gasoline Vehicle
Authors: Giechaskiel Barouch , Valverde Victor , Kontses Anastasios , Suarez-Bertoa Ricardo , Selleri Tommaso , Melas Anastasios , Otura Marcos , Ferrarese Christian , Martini Giorgio , Balazs Andreas , Andersson Jon , Samaras Zisis , Dilara Panagiota
Published: August 2021

Gaseous emissions of modern Euro 6d vehicles, when tested within real driving emissions (RDE) boundaries, are, in most cases, at low levels. There are concerns, though, about their emission performance when tested at or above the boundaries of ambient and driving conditions requirements of RDE regulations. In this study, a Euro 6d-Temp gasoline direct injection (GDI) vehicle with three-way catalyst and gasoline particulate filter was tested on the road and in a laboratory at temperatures ranging between −30 °C and 50 °C, with cycles simulating urban congested traffic, uphill driving while towing a trailer at 85% of the vehicle’s maximum payload, and dynamic driving. The vehicle respected the Euro 6 emission limits, even though they were not applicable to the specific cycles, which were outside of the RDE environmental and trip boundary conditions. Most of the emissions were produced during cold starts and at low ambient temperatures. Heavy traffic, dynamic driving, and high payload were found to increase emissions depending on the pollutant. Even though this car was one of the lowest emitting cars found in the literature, the proposed future Euro 7 limits will require a further decrease in cold start emissions in order to ensure low emission levels under most ambient and driving conditions, particularly in urban environments. Nevertheless, motorway emissions will also have to be controlled well.