bluuebunny/crossref_metadata_2025 huggingface dataset:
Mediating effect of coping behavior on the relationship between driving stress and traffic accident risk
Authors: Lee Soonyeol , Lee Soonchul
Published: January 2020

The present study was conducted to determine the effects of driving stress on traffic accident risk. Specifically, this study verified the effects of driving stress on drivers' coping behaviors and the aptitude of mediating models through which coping behavior types affect traffic accident risk. As a result, driving stress directly increased traffic accident risk and indirectly affected them through(good and bad) coping behavior types. This indicates that driving stress directly and indirectly affect traffic accident risk by the medium of(good and bad) coping behavior types in multilateral ways.(Commercial and leisure-purposed) driving purposes showed significant differences in the relations between driving stress and traffic accident risk. Specifically, commercial drivers were affected by driving stress, compared to leisure-purposed drivers. As they were unable to defer or abandon driving even under driving stress, commercial drivers responded to the stress more sensitively and increased traffic accident risk by selecting inappropriate(bad) coping behaviors. The results show that the mere concentration on driving stress management cannot sufficiently lower the traffic accident risks caused by driving stress. This is because driving stress have indirect influences on traffic accident risk. Hence, it will be necessary to seek how to reduce driving stress and control coping behavior types in order to lower the traffic accidents risk by the stress.
Development of Holland Vocational Interest Inventory(short form) and investigation of Holland's hypotheses
Authors: Heo ChangGoo
Published: January 2020

This study were preformed for two purposes. The first is to develop a Korean vocational interest inventory based on Holland theory(short version) and second is to investigate of Holland's hypotheses(circular order and circumplex). With a sample of 149 high school students(male 58, female 91) and 224 college students(male 132, female 92), the main results were as follows. First, the scale which developed as 72 items in this study has shown acceptable reliabilities and construct validities, that is, this short form interest inventory could be used to verify student's vocational interest in conjunction with existing inventories. Second, the radnomization test using RANDALL(Tracey, 1997) has shown that the circular order hypothesis were supported. Third, in the results of confirmatory factor analysis, the modle that Holland's circumplex hypothesis was not adapted, has had better fit(TLI, RMSEA) than the model which Holland's circumplex hypothesis was adapted. Forth, the results of MDS showed the RIASEC interest types could be explained well through Sociaility and Confirmity of Hogan(1983). In summary, Holland's circular order hypothesis was supported but the circumplex hypothesis was not supported to Korean student's data. Finally, the implications and limitations were discussed.
Assessment Center for selection of university student
Authors: Heo ChangGoo
Published: January 2020

This study were preformed for verifying the applicability of Assessment Center(AC) for selection of university student. First, the results of decision study of generalizability theory(D study) has shown acceptable reliabilities. So, we could think that this AC was designed properly. Second, the enrolled students of the university have said that the competencies rated in this AC were important for performing study and adapting to school. And participants in this AC reported they have felt fairness and they could have done their best. It means that this AC had validity. Third, generalizability study(G study) has shown dimension effect(21.1%) was higher than rator effect(10.2%). And, in the MTMM analysis, it were found both dimension effect and exercise effect. Forth, in relation analysis between AC ratings and the various records of participants, ‘Self-led Study’ related with ‘Records of Language’ positively, ‘Discussion Skill’ related with ‘Public Anxiety’ negatively, ‘Challenge’ related with ‘Extraversion, Self Efficacy, and Record of Award off campus’ positively and with ‘Anxiety to unfamiliar’ negatively, ‘Creativity’ related with ‘Extraversion’ positively, ‘Adapting to Change’ related with ‘Emotional Stability’ positively, and ‘Interpersonal Competencies’ related with ‘Performance Anxiety and Public Anxiety’ negatively. In short, this AC has shown applicability as selection tool for university student. Finally, the implications and limitations were discussed.
THE COMPARISON OF CHICKEN FARMING BUSINESS ON VARIOUS PATTERNS IN NORTH BENGKULU REGENCY
Authors: Harianto Harianto , Arianti Nyayu Neti , Asriani Putri Suci
Published: January 2020

This study aims to calculate and compare the income and the level of efficiency of poultry farming with various business patterns, namely "Mandiri" or independent, partnering with national company and partnering with foreign company. Respondents were taken in a census method, consist of 11 independent farmers, 21 farmers who partnered with national company and 10 farmers who partnered with foreign company. Income is calculated by subtracting revenue and costs. Business efficiency is determined by the R/C Ratio. Meanwhile, the comparison of incomes were analyzed by the t-test. The results showed that the average income of independent livestock business is IDR 5.536,95/head, the national partnership is IDR 2.523,20/head, and those with foreign partner is IDR 3.162,74/head. While The efficiency level of independent pattern is 1,15, 1,09 for national partnership pattern and 1,10 for foreign partnership. The results of the t-test at the 95% confidence level indicate that the income of independent livestock is higher than those in nationally and foreign-partnered farms. While the nationally-partnered business is not higher than the foreign-partnered.
DEVELOPING CRITICAL THINKING SKILLS THROUGH MICROTEACHING
Authors: Lestari Ika Wahyuni
Published: January 2020

This study aimed to explore how microteaching improved the students’ critical thinking skills. The method used was qualitative research. The procedure of collecting the data was assigning 20-minute microteaching to nine groups of preservice teachers over nine weeks of teaching and learning process. In a group of two to three, they were asked to demonstrate their understanding on how to teach English to young learners based on a given topic. Peer feedback and teacher feedback were also given as a post-activity. Two preservice teachers were interviewed to explore their views on how the microteaching model influenced their critical thinking. The results showed that all stages of the microteaching model - the preparation and planning, the 20 minutes microteaching, peer feedback, and teacher feedback - enhanced their critical thinking skills.
Existence results for fractional neutral integro-differential systems with nonlocal condition through resolvent operators
Authors: Mallika D. , Baleanu D. , Suganya S. , Arjunan M. Mallika
Published: January 2020

The manuscript is primarily concerned with the new existence results for fractional neutral integro-differential equation (FNIDE) with nonlocal conditions (NLCs) in Banach spaces. Based on the Banach contraction principle and Krasnoselskii fixed point theorem (FPT) joined with resolvent operators, we develop the main results. Ultimately, an representation is also offered to demonstrate the accomplished theorem.
Combining Evolution and Learning in Computational Ecosystems
Authors: Strannegård Claes , Xu Wen , Engsner Niklas , Endler John A.
Published: January 2020

Although animals such as spiders, fish, and birds have very different anatomies, the basic mechanisms that govern their perception, decision-making, learning, reproduction, and death have striking similarities. These mechanisms have apparently allowed the development of general intelligence in nature. This led us to the idea of approaching artificial general intelligence (AGI) by constructing a generic artificial animal (animat) with a configurable body and fixed mechanisms of perception, decision-making, learning, reproduction, and death. One instance of this generic animat could be an artificial spider, another an artificial fish, and a third an artificial bird. The goal of all decision-making in this model is to maintain homeostasis. Thus actions are selected that might promote survival and reproduction to varying degrees. All decision-making is based on knowledge that is stored in network structures. Each animat has two such network structures: a genotype and a phenotype. The genotype models the initial nervous system that is encoded in the genome (“the brain at birth”), while the phenotype represents the nervous system in its present form (“the brain at present”). Initially the phenotype and the genotype coincide, but then the phenotype keeps developing as a result of learning, while the genotype essentially remains unchanged. The model is extended to ecosystems populated by animats that develop continuously according to fixed mechanisms for sexual or asexual reproduction, and death. Several examples of simple ecosystems are given. We show that our generic animat model possesses general intelligence in a primitive form. In fact, it can learn simple forms of locomotion, navigation, foraging, language, and arithmetic.
Pemaknaan Lasara dalam Mitologi Nias
Authors: Hidayati Dyah
Published: January 2020

AbstractLasara is a mytological object being that is often symbolized in Nias material culture such as osa-osa, sarcofagus, wooden coffin, grave, lasara on village gate, traditional house ornaments, and sword handle. This comparative study-enhanced descriptive-analytical research method is aimed at finding connection between lasara, which is a part of Nias people mythology, and its interpretation through the outlying elements to obtain a complete understanding of lasara. The analysis reveals that in a society where mythology is an innate value, lasara is understood as a symbol of a ride related with religious and social aspects. Lasara is symbolized as a boat used in the migration of Nias people through the sea, as well as a spiritual ride in its religious life.AbstrakLasara merupakan makhluk mistis yang banyak diwujudkan dalam budaya materi di Nias seperti osa-osa, sarkofagus, peti jenazah kayu, bangunan kubur, lasara pada gerbang desa, ornamen rumah adat, dan hulu pedang. Untuk menjawab permasalahan mengenai pemaknaan lasara dalam pemahaman masyarakat Nias digunakan metode deskriptif analitik yang diperkuat oleh studi komparatif yang bertujuan untuk menarik benang merah antara objek yang dikenal sebagai lasara yang menjadi bagian dari mitologi masyarakat Nias dengan pemaknaannya melalui aspek-aspek yang melatarbelakanginya sehingga dapat diperoleh pemahaman yang utuh terhadap salah satu bentuk kebudayaan di daerah Nias tersebut. Dari analisis tersebut dapat terjawab bahwa dalam pemahaman masyarakatnya yang masih sangat terikat oleh mitologi, lasara dimaknai sebagai simbol yang berkaitan dengan struktur sosial serta simbol wahana terkait dengan aspek religi dan sosial. Lasara sebagai wahana dikaitkan dengan bentuk perahu yang berhubungan dengan proses migrasi orang Nias melalui jalur lautan, serta sebagai kendaraan arwah dalam kehidupan religinya.
Obyek-Obyek Ideofak dari Situs Kota Cina: Refleksi Kehidupan Religi Penghuninya
Authors: Soedewo Ery
Published: January 2020

AbstractThe variety of aspects of life of the people settling in the Kota Cina in the past is reflected through the archaeological data gathered through a number of observations and people findings. One of the aspects revealed is the religious aspect. The existing diverged ideofac indicates the diversified religius background as well as the people. The Hindus (Siva and VaisnavaI, Buddhists, and Animists coexisted in harmony in the Kota Cina in its heydey as an international port.AbstakRagam aspek kehidupan manusia pendukung peradaban Kota Cina di masa lalu tercermin pada data arkeologis yang dihimpun melalui sejumlah penelitian dan temuan masyarakat. Salah satu aspek yang terungkap adalah kehidupan religinya. Keragaman ideofak yang ada mencerminkan keragaman latar belakang religinya, sekaligus asal pendukung budayanya. Penganut Hindu (Śaiwa dan Waiṣṇawa), Buddha, dan penganut animisme hidup berdampingan di Kota Cina pada masa jayanya dahulu sebagai suatu bandar internasional.
Sebaran Sumatralith Sebagai Indikasi Jarak Dan Ruang Jelajah Pendukung Hoabinhian
Authors: Wiradnyana Ketut
Published: January 2020

AbstractA river was highly significant in search of a settlement in the past, which is why there have been numerous findings of pre-historic sites and activities at watersheds. Findings of stone artifacts of the same kind at some estuaries indicate similar environment exploitations. Such exploitations could have been at relatively the same time or at a different time. To know the past activity more accurately, morphological and technological analyses on the stone artifacts need implementing.Furthermore, a comparative analysis on the findings of similar artifacts along with their distribution is an inseparable method in investigating the culture and the distance and space of the pre-historic men. The Sumatralith distribution at the Bay of Belawan’s estuaries indicates exploitations by men inhabiting the site of Bukit Kerang Percut by using the river channel as the hunting navigation to the highland of Tanah Karo covering 25-30 km of exploration area. Such interpretation indicates the direction of exploration from the lowland (the site of Bukit Kerang Percut) to the highland of Tanah Karo. The existence of the site of Bukit Kerang Percut and Sumatralith distribution also indicate the settlement of Hoabinh culture people at the highland whose exploration space covered the lower land.AbstrakSungai memiliki peran penting dalam menentukan lokasi hunian pada masa lalu. Oleh karena itu, situs-situs masa prasejarah dengan aktivitasnya kerap ditemukan di Daerah Aliran Sungai. Temuan artefak batu yang sejenis di beberapa sungai yang bermuara sama, mengindikasikan adanya upaya eksploitasi lingkungan yang sama. Eksploitasi dimaksud dapat dalam waktu yang relatif sama atau dapat juga dalam waktu yang berbeda. Untuk mengetahui aktivitas masa lalu dengan lebih baik maka diperlukan analisa morfologi dan teknologi atas artefak batu dimaksud, serta temuan lain yang dapat memberikan interpretasi yang lebih baik. Selain itu adanya perbandingan dengan artefak sejenis pada situs terdekat dan diketahuinya sebaran artefak tersebut, merupakan bagian yang sangat penting untuk mengetahui budaya dan jarak serta ruang jelajah manusia masa prasejarah. Sebaran sumatralith yang ditemukan di sungai-sungai yang bermuara di Teluk Belawan mengindikasikan adanya eksploitasi manusia yang menghuni di Situs Bukit Kerang Percut, dengan memanfaatkan alur sungai sebagai navigasi aktivitas perburuan ke dataran tinggi Tanah Karo, dengan jarak jelajah berkisar 25-30 km. Interpretasi tersebut menunjukkan adanya arah jelajah dari dataran rendah (Situs Bukit Kerang Percut) ke dataran tinggi Tanah Karo. Hal lainnya yang dimungkinkan atas keberadaan situs Bukit Kerang Percut dan sebaran sumatralith adalah, adanya indikasi hunian pendukung budaya Hoabinh di dataran tinggi, yang memiliki ruang jelajah hingga ke dataran yang lebih rendah.
Dilema Pemugaran Bangunan Rumah Candu Dalam Menghindari Miskomunikasi Pemberantasan Narkoba
Authors: Simatupang Defri Elias
Published: January 2020

AbstractThis writing aims at reviewing a conservatory activity over a heritage building of an opium house, which may provoke miscommunication. Such miscommunication mas arise from the misinterpretation that the conservation attempt of the opium house as a heritage bulding is counterproductive to the illegal drug eradication program. The two seemingly contradictory sides are the history conservation activist and the people who support the illegal drug eradication. This paper uses an inductive reasonong that commences from the discussion of any data available then draws a general conclusion. The acquired data is then analyzed and interpreted to be concluded into a proposed solution model of an archaeological conservation ploicy to prevent from a possible miscommunication that will lead to a conflict.AbstrakTulisan ini mencoba untuk meninjau sebuah kegiatan konservasi bangunan cagar budaya (BCB) berupa rumah candu yang diduga rentan menimbulkan terjadinya miskomunikasi. Miskomunikasi dalam hal ini disebabkan karena pesan untuk melestarikan rumah candu sebagai BCB justru ditangkap sebagai usaha yang tidak mendukung program pemberantasan narkotika dan obat-obat terlarang (narkoba). Kedua pihak tersebut adalah para aktivis pelestari sejarah dengan publik yang dalam hal ini aktif mendukung pemberantas narkoba. Tulisan ini menggunakan penalaran induktif yang berawal dari pembahasan setiap data yang selanjutnya menarik sebuah kesimpulan yang bersifat umum. Data-data yang didapatkan dianalisis dan diinterpretasi untuk ditarik menjadi tawaran solusi model kebijakan konservasi arkeologi demi menghindari terjadinya miskomunikasi yang berujung ke konflik.
BOOK REVIEW: Mohawk Interruptus: Political Life Across the Borders of Settler States
Authors: Mixon Chelsea
Published: January 2020

Book review of Audra Simpson's (2014) Mohawk Interruptus: Political Life Across the Borders of Settler States
Contested Images: Debates on Nudity, Sexism, and Porn in The Body Politic, 1971–1987
Authors: Mezo González Juan Carlos
Published: January 2020

This article examines debates on nudity, sexism, and pornography in the Canadian gay and lesbian newspaper The Body Politic, tracing its use of images and people’s responses to them over time. In the 1970s, concerns about sexism and the objectification of the body shaped discussions over sexual and erotic imagery. In the 1980s concerns about pornography were more current, since they mirrored the then-contemporary debates over pornography and censorship. Drawing upon archival sources and oral histories, the article argues that TBP’s visual culture—particularly its sexual and erotic imagery—played a key role in the paper’s community-building project. The article also shows how responses to images reflect a deep ambivalence, and the conflicting perspectives shaping the paper’s production and reception. While liberationist politics, feminist theory, and ideas of a “gay community” influenced the paper throughout the 1970s and 1980s, the meanings that people ascribed to such concepts were diverse and sometimes incompatible.
The Experience of Detailing the Results of Magnetic Surveys of Archaeological Sites by Electrical Exploration Methods
Authors: Balkov E. V. , Pozdnyakova O. A. , Dyadkov P. G. , Karin Yu. G. , Shaparenko I. O. , Fadeev D. I.
Published: January 2020

Now, the work aimed at extracting maximum information about archaeological objects using geophysical methods is relevant. The possibilities for this give us the integration of various geophysical methods. In 2018–2019, electrical exploration works were carried out at the archaeological site Ust-Tartas mounds (Western Siberia). The sites for these works were selected based on magnetic survey data. The purpose of the research was to obtain additional information on the parameters of archaeological objects and to compare the possibilities of different geophysical methods. Several different magnetic anomalies were chosen for the studies. Methods of electromagnetic frequency sounding, electrotomography and georadiolocation were used. We were able to refine the length, width, depth of objects, and their configuration. The type of objects studied (burial or pit, settlement complex) is defined. The most informative results, which complement the magnetic survey data, are obtained using the electrotomography method.
Serverless Mobile Applications Development
Authors: Markhakshinov A. L. , Tonkhonoeva A. A. , Urmakshinova E. R.
Published: January 2020

Principles of mobile applications development, requiring no server code, are described. Database, user authentication and notification sending functions are suggested to be implemented by BaaS model (Backend as a Service). Example architecture of serverless mobile application using Google Firebase cloud services is shown. Brief description of basic interactions between serverless architecture components is given.
About the grammar of the Khakas Language by N. P. Dyrenkova
Authors: Chebochakova I. M.
Published: January 2020

In 2018, the first grammar of the Khakass language, written within the academic traditions of that time by the fa-mous Turkologist Nadezhda Petrovna Dyrenkova, was 80 years old. Also, may 31, 2019 marks the 120th anniversary of the birth of this outstanding scientist. These two dates, as well as the need to familiarize the Khakass public with the publication, which has become a bibliographic rarity, and its author in the light of the increasing interest in the society to the Khakass language explains the relevance of this article. Nadezhda Petrovna's research talent allowed her to create the first scientific grammar of the modern Khakass language, which served as the basis for writing the following aca-demic grammar. One of its important aspects can be considered to be the focus on the explanation of the peculiarities of the use of units of language in speech, that is, its practical nature.
The Effects of Cognitive-Behavioral Counseling on Self-esteem and the Tendency of Mobile Phone Addiction
Authors: Farjantoky Belardo , Sunawan Sunawan , Mulawarman Mulawarman
Published: January 2020

The mobile phone users in students are increased dramatically. Unfortunately, excessive use of mobile phone could cause addiction. The addiction to mobile phone affecting the personal and social life of students. Therefore, authors decided to identify the effect of cognitive-behavioral counseling interventions on self-esteem and the tendency of mobile phone addiction in students of Vocational School 1 Muhammadiyah Semarang. Participants in the pretest were 120 students. This study used a quasi-experiment method, pretest-posttest control group design involving 12 students, randomly divided to experiment (6 students) and control group (6 students). The samples were selected using purposive sampling with low self-esteem criteria and a high tendency for mobile phone addiction. The MANCOVA test results proved that cognitive-behavioral counseling had an effect on self-esteem (F1.8=265.28; ηp2=0.963; p<0.001), and the tendency of mobile phone addiction (F1.8=1115.90; ηp2=0.973; p<0.001). The findings of this study proved that there were effects of cognitive-behavioral counseling interventions on self-esteem and the tendency of mobile phone addiction.
Moral Disengagement and Classroom Incivility against the Social Responsibility Character of Junior High School Students
Authors: Susilawati Susilawati , Wibowo Mungin Eddy , Sunawan Sunawan
Published: January 2020

Nowadays social responsibility is significant to investigate. It is because in the academic world there are a number of students having low social responsibility. This behavior is realized by unfair actions in groups, bullying or intimidation practice. Concerning this phenomenon, the current study aimed at analyzing the prediction of students’ social responsibility from the perspective of moral disengagement and incivility. This correlational study involved 636 students with a portion of 49.5% of male students and 50.5% of female students. They were selected using cluster sampling from two junior high schools in Central Java. After that, these students were asked to fill in a moral disengagement scale, and classroom incivility scale. The results showed that moral disengagement and incivility significantly predicted social responsibility (R=0.336, R2=0.113, F=6.079, and P<0.01). Specifically, the findings of this study confirmed that the aspects of Moral Justification and Dehumanization, as well as intentional incivility, predict students’ social responsibility.
The Effectiveness of Psychoeducational Group with Group Exercises Technique to Improve Student’s Self-Efficacy
Authors: Pangestuti Riana Wibi , Wibowo Mungin Eddy , Japar Muhammad
Published: January 2020

Self-efficacy is a determining factor to achieve the learning objectives. Therefore, self-efficacy is important to be measured and improved. This study aimed to examine the effectiveness of a psychoeducational group with exercises techniques to improve students’ self-efficacy. This study was carried out by using a pretest-posttest control group design by involving 2 groups, the experimental and control group. The data from these groups were analyzed using repeated-measure MIX MANOVA. Meanwhile, the authors used self-efficacy scale (α=0.911) to collect the data of 14 students. The results showed that there were effects of time in the improvement of students' self-efficacy (F(2)=1,746; p<0.05), group members effect (F(3,984)=8,442; p<0.05), and the effect of time interacting with group members (F(1,293)=0.045; p<0.05). It can be concluded that the psychoeducational group with exercises techniques is effective to improve students’ self-efficacy by regarding the duration of intervention, group member, and time interaction with group members. This study implication to the guidance and counseling services will be discussed.
Patients with dementia – a challenge for pharmacist
Authors: Marineci Cristina Daniela , Ștefănescu Emil , Chiriţă Cornel
Published: January 2020

Dementia is an umbrella term that refers to progressive and irreversible cognitive decline. Dementia affects several cognitive domains: memory, language, attention, execution function, perceptual and motor skills, and social networking. Behavioral and psychiatric symptoms complicate dementia, being difficult to manage. Depending on the causes and the clinical presentation, there are several types of dementia. Alzheimer dementia is the most common type, and it is believed to be due to the interneuronal deposition of insoluble beta-amyloid plaques and intraneuronal neurofibrillary tangles consisting of tau protein, which eventually lead to neuronal destructions with cholinergic deficiency. The medicines currently used in Alzheimer disease therapy are cholinesterase inhibitors and NMDA receptor antagonists. These drugs are not disease modifiers and do not address the cause; they act symptomatic-pathogenically, slowing down cognitive decline. Psychiatric and behavioral symptoms associated with dementia are treated with appropriate medication. From the therapeutic regimen of patients with Alzheimer disease it is preferable to eliminate drugs with anticholinergic and sedative effects.
New insights in the pharmacotherapy of glaucoma
Authors: Mititelu-Tarțău Liliana , Buca Beatrice Rozalina , Fotache Paula Alina , Bogdan Maria , Popa Eliza Grațiela , Gafițanu Carmen
Published: January 2020

Glaucoma often requires an individualized treatment, combining pharmacotherapy (topical and sometimes systemic), with laser treatment and surgery. Prostaglandin analogues, beta‑blockers and adrenergic agonists are still the gold standard in glaucoma therapy, as single agents or combined. The modern therapy of glaucoma involves combinations of drugs with neuroprotectors of the optic nerve, Rho kinase inhibitors, vasopressin receptors agonists, monoclonal antibodies, agonists of adenosine receptors, and serotoninergic drugs. A modern trend in glaucoma treatment highlights new technologies using stem cells and gene therapy: thus, the administration of genes, gene ablation and stem cell transplant are promising approaches in the management of glaucoma.
Solving the Challenging Synthesis of Highly Cytotoxic Silver Complexes Bearing Sterically Hindered NHC Ligands with Mechanochemistry
Authors: Beillard Audrey , Quintin François , gatignol jeremie , Retailleau Pascal , Renaud Jean-Luc , Gaillard Sylvain , Métro Thomas-Xavier , Lamaty Frédéric , Bantreil Xavier
Published: January 2020

The use of ball-mills enabled the straightforward synthesis of a variety of silver(I) complexes featuring challenging NHC ligands. Sterically hindered including electron-poor or with very low solubility imidazolium salts were grinded with silver(I) oxide to furnish heteroleptic or homoleptic complexes in high yield and short reaction times. The synthesis of heteroleptic bis-NHC silver(I) complexes was also performed for the first time in a ball-mill. The efficiency and rapidity of the mechanochemical approach enabled the generation of a library of unprecedented NHC silver complexes, which cytotoxicity on HCT116 colorectal cancer cell line was evaluated providing a rare example of medicinal mechanochemistry. The cationic silver complexes were found more potent than the neutral analogues, with IC50 values down to 21 nM, 256 times more potent than cisplatin.
Universal Scaling and Real-Time Monitoring of the Production of Liquid Exfoliated Graphene
Authors: Stafford Jason , Uzo Nwachukwu , Farooq Usmaan , Favero Silvia , Wang Si , Chen Hseuh-Hung , L'Hermitte Anouk , Petit Camille , Matar Omar
Published: January 2020

Shear-assisted liquid exfoliation is a primary candidate for producing defect-free two-dimensional materials from labs to industry. Diverse hydrodynamic conditions exist across production methods, and combined with low-throughput, high-cost characterization techniques, strongly contribute to the wide variability in performance and material quality. Through investigations on strikingly different flow regimes, and using graphene as the prototypical two-dimensional material, we �find that scaling of production depends on local stress fi�eld distributions and precursor residence time. We report a novel indirect diffuse reflectance method to measure graphene concentration in real-time, using low-cost optoelectronics and without the need to remove the precursor material from the heterogeneous dispersions. We show that this high-throughput, in situ approach has broad applicability by controlling the number of atomic layers on the fly, rapidly optimising green solvent design for maximum yield, and viewing live production rates. Combining insights on the hydrodynamics of exfoliation with this scalable monitoring technique, targeted process intensi�fication, quality control, batch traceability and individually customisable materials on-demand are possible.
Real-Time Degradation Dynamics of Hydrated Perfluoroalkyl Substances (PFASs) in the Presence of Excess Electrons
Authors: Yamijala Sharma , Shinde Ravindra , Wong Bryan
Published: January 2020

Perfluoroalkyl substances (PFASs) are synthetic chemicals that are harmful to both the environment and human health. Using self-interaction-corrected Born-Oppenheimer molecular dynamics simulations, we provide the first real‐time assessment of PFAS degradation in the presence of excess electrons. In particular, we show that the initial phase of the degradation involves the transformation of an alkane-type C-C bond into an alkene-type C=C bond in the PFAS molecule, which is initiated by the trans elimination of fluorine atoms bonded to these adjacent carbon atoms.
Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling
Authors: Bersini Simone , Lytle Nikki K , Schulte Roberta , Huang Ling , Wahl Geoffrey M , Hetzer Martin W
Published: January 2020

Nucleoporin 93 (Nup93) expression inversely correlates with the survival of triple-negative breast cancer patients. However, our knowledge of Nup93 function in breast cancer besides its role as structural component of the nuclear pore complex is not understood. Combination of functional assays and genetic analyses suggested that chromatin interaction of Nup93 partially modulates the expression of genes associated with actin cytoskeleton remodeling and epithelial to mesenchymal transition, resulting in impaired invasion of triple-negative, claudin-low breast cancer cells. Nup93 depletion induced stress fiber formation associated with reduced cell migration/proliferation and impaired expression of mesenchymal-like genes. Silencing LIMCH1, a gene responsible for actin cytoskeleton remodeling and up-regulated upon Nup93 depletion, partially restored the invasive phenotype of cancer cells. Loss of Nup93 led to significant defects in tumor establishment/propagation in vivo, whereas patient samples revealed that high Nup93 and low LIMCH1 expression correlate with late tumor stage. Our approach identified Nup93 as contributor of triple-negative, claudin-low breast cancer cell invasion and paves the way to study the role of nuclear envelope proteins during breast cancer tumorigenesis.
Application of confocal laser scanning microscopy in dendrochronology
Authors: Balzano Angela , Novak Klemen , Humar Miha , Čufar Katarina
Published: January 2020

We used the Confocal Laser Scanning Microscope (CLSM) Olympus LEXT OLS5000 for non-destructive observation and image analysis of wood anatomy traits in growth layers of tree species from different climatic zones. In European beech (Fagus sylvatica), where tree rings can generally be recognised, we discuss the changes in tree-ring structure due to adverse effects (insect attacks). Growth layers in Mediterranean Aleppo pine (Pinus halepensis) from south-eastern Spain are not always annual and contain numerous intra-annual density fluctuations (IADFs). Ocote pine (Pinus oocarpa) growing at high elevation in Honduras showed growth layers with clear growth ring boundaries and IADFs. In both pines, CLSM allowed us to recognise and measure tracheid parameters to define density fluctuations. In tropical true mahogany (Swietenia macrophylla) from Venezuela and cedrela (Cedrela odorata) from Costa Rica, we studied the growth layers with variable dimensions of vessels demarcated by marginal axial parenchyma.
Wood identification using non-destructive confocal laser scanning microscopy
Authors: Čufar Katarina , Balzano Angela , Krže Luka , Merela Maks
Published: January 2020

Exact wood identification is usually based on observation of wood features under the microscope. For this, we have to take a sample of the wood from the object and cut thin slides, possibly of all three anatomical sections. Such destructive sampling is often not possible on valuable historical objects, and therefore there is a need for non-destructive approaches. The objective of the study is to present the potential of Confocal Laser Scanning Microscopy (CLSM) using an Olympus LEXT OLS5000 for the identification of wood. We present work on an example of a gothic sculpture, “St. George Defeating the Dragon”. Conventional sampling and microscopical wood identification showed that St. George is made of Norway spruce (Picea abies), and the dragon of poplar (Populus sp.) or willow (Salix sp.). We present crucial features needed for the identification of these species and the limitations with identification if the samples are too small. Finally, we demonstrate the possibility of wood identification of the abovementioned species using CLSM on wood samples without special preparation of the surfaces. CLSM enabled us to observe all the features needed for wood identification.
Adhesion of bacteria to wood coatings
Authors: Bohinc Klemen , Kekec David , Petrič Marko
Published: January 2020

Bacterial adhesion to surfaces and subsequent biofilm formation are the main causes of chronic infections with a negative impact on human health, and this is a problem in the process of manufacturing furniture. This is an important issue, relevant also to the selection and production of furniture, where there is a focus on the development of products with antibacterial surfaces to which microorganisms do not adhere. The focus of our research was to test selected wood coatings (linseed oil, water-borne stain, nitrocellulose varnish, nano-coating) with regard to the adhesion of Pseudomonas aeruginosa, where we used a beech plywood as the test surface. The topography of the test surfaces and the number of adhered bacteria were observed on SEM micrographs. The results indicate that the maximum number of bacteria adhered to the surface coated with linseed oil. In the future, extensive and in-depth studies will be needed to confirm and obtain the required results.
Analisis Sifat Fisik Semen Organik Terbuat dari Bahan Limbah Daur Ulang
Authors: Syarif Muhammad
Published: January 2020

Penelitian ini bertujuan sebagai penyelamatan lingkungan dan penemuan bahan bangunan alternatif terbaru. Dalam penelitian ini, telah menghasilkan semen organik yang merupakan semen alternatif terbaru selain dari semen portland yang dibuat melalui sistem daur ulang limbah organik, fly ash, bottom ash, dan substitusi tanah mediteran. Metode yang digunakan dalam penelitian ini adalah pengujian laboratorium. Pengujian digunakan untuk menentukan unsur senyawa kimia pada masing-masing bahan utama semen organik. Dari hasil analisis senyawa kimia semen organik melalui metode pengujian laboratorium, telah ditemukan indikasi yang mirip dengan senyawa kimia semen portland dalam bentuk: CaO; 65,36%, SiO2 18,84%, Al2O3 6,33%, Fe2O3 2,29%, SO3 3,64%, MgO 1,35%, C3S 66, 72%, C2S 3,98%, C3A 12,9%, dan C4Af 6,97%. Bleeding beton semen organik untuk 1 m3 adalah 23,88 ml/cm2, lebih rendah dari bleeding beton semen portland yang mencapai 31,83 ml/cm2. Kadar udara beton semen organik dalam 1 m3 adalah 2,2%, sedang kadar udara beton semen portland mencapai 1,9%. Berat unit semen organik diperoleh 1.200 kg/m3, lebih ringan dari semen portland yang mencapai 1.250 kg/m3.
THE EFFECTIVENESS OF PRACTICUM KIT AS A LEARNING MEDIA TO TRAIN SPS ON REACTION LAW
Authors: Trimayanto Sigit , Novita Dian
Published: January 2020

This study aims to produce the Practical KIT along with its devices that are effectively used as learning media to train students SPS on the sub material of the Reaction Rate Law. The method used in this study is Research and Development design. The research instrument used consisted of a sheet of pre-test and post-test. Data analysis was carried out in descriptive quantitative to determine the effectiveness of Practical KIT along with the devices developed. The media is said to be effective if it meets 2 requirements, namely the percentage of classical completeness <85% and N-gain value <0.3. The developed media has been declared effective as indicated by the increase in the value of cognitive learning outcomes in the "Medium" and "High" categories with 100% classical completeness, an increase in the value of science process skills of students after using the Practical KIT media. "With classical completeness reaching 91.67%.
PKU Bagi MI Muhamamdiyah Rambeanak 2 Kabupaten Magelang, Melalui Alat Peraga Edukatif (APE)
Authors: Oktradiksa Ahwy , Aufa Minzani
Published: January 2020

Madrasah Ibtidaiyah Muhamadiyah (MIM) 2 Rambeanak memiliki siswa sebanyak 127 orang, guru sebanyak 8 orang, dan didirikan sejak tahun 1947, meski sudah setengah abad didirikan, namun sampai saat ini masih mengalami sejumlah kendala, di antaranya adalah 1) kondisi obyektif dari guru dan sumber daya manusia dan sumber daya media pembelajaran berupa Alat Peraga Edukatif (APE) sehingga berdampak pada keterbatasan dalam mendukung proses pembelajaran berkualitas; 2) minimnya dukungan stakeholders madrasah dalam pengembangan madrasah baik secara moril maupun materiil. Sehubungan dengan hal tersebut, maka akan dilakukan kegiatan Program Kemitraan Universitas (PKU) yang bertujuan untuk peningkatan mutu madrasah menuju madrasah dengan proses pendidikan yang berkualitas melalui pendampingan pembuatan APE bagi guru. Metode yang digunakan pemberdayaan masyarakat partisipatif Participatory Rural Apraisal (PRA). Adapun kesimpulan yang dapat diberikan dalam pelaksanaan PKU di MIM 2 Rambeanak sebagai berikut : 1) Setelah dilakukan pendekatan melalui sosialisasi tentang pentingnya APE, maka guru bisa membuat dan berdampak pada gaya guru mengajar yang menarik dan hasil belajar siswa menjadi baik, 2) Setelah guru melakukan diseminasi hasil pembuatan APE, maka guru menjadi lebih kreatif dengan memanfaatkan bahan yang ekonomis dan tertarik untuk membuat lebih banyak lagi APE dengan ide yang brilian berdasarkan pengalaman yang sudah dilakukan selama kegiatan PKU berlangsung. Madrasah Ibtidaiyah Muhamadiyah (MIM) 2 Rambeanak has 127 students, 8 teachers, and was founded in 1947, although it has been established for half a century, but to date there are still a number of obstacles, including 1) the objective conditions of the teacher and human resources and instructional media resources in the form of Educational Teaching Aids (APE) so that the impact on limitations in supporting the quality learning process; 2) the lack of support from madrasa stakeholders in madrasa development both morally and materially. In connection with this, the University Partnership Program (PKU) activity will be carried out which aims to improve the quality of madrasas towards madrasas with a quality education process through mentoring making APE for teachers. The method used is Participatory Rural Appraisal (PRA) participatory community empowerment. The conclusions that can be given in the implementation of PKU in MIM 2 Rambeanak are as follows: 1) After an approach through socialization about the importance of APE, the teacher can make and have an impact on the teacher's teaching style that is interesting and student learning outcomes become good, 2) After the teacher does the dissemination of the results of making APE, the teacher becomes more creative by utilizing economical materials and is interested in making more APE with brilliant ideas based on experience that has been done during PKU activities.
Patrones alimenticios y sobrepeso-obesidad escolar. Estudio comparativo sector público y privado, zona metropolitana Zacatecas-Guadalupe.
Authors: Almeida Perales Cristina , Gutiérrez Razo Ana Christian , Ruiz de Chavez-Ramírez Dellanira , García Zamora Pascual Gerardo
Published: January 2020

Introducción. El sobrepeso y obesidad escolar en México representa un problema de salud pública. Examinar el consumo de alimentos resulta obligado para comprender el fenómeno e identificar áreas de oportunidad en intervenciones educativas. Objetivo. Determinar los patrones alimenticios y prevalencia de sobrepeso-obesidad en escolares del sector público y privado. Material y Métodos. Estudio transversal y comparativo en escolares (5-11 años) de escuelas públicas y privadas de la zona metropolitana Zacatecas-Guadalupe. De una población de 31,580 niños se seleccionaron a 372 escolares de 8 escuelas públicas y 2 privadas bajo un muestreo aleatorio estratificado. Se estimó el patrón alimenticio y diagnóstico nutricional conforme a criterios de la OMS. Mediante el programa SPSS 20 se procesó la información estadística descriptiva e inferencial. Resultados. Aun cuando la prevalencia de sobrepeso-obesidad fue mayor en escuelas públicas (36.8%) que privadas (28.2%), no hubo diferencias significativas (p>0.05). Predominaron en ambos grupos, patrones alimenticios de ingesta por arriba de lo recomendado en los grupos de azúcares, cereales, lácteos y alimentos de origen animal. Conclusiones. Se identificó una dieta occidentalizada que favorece la malnutrición por exceso. Urgen acciones de promoción de salud y políticas que garanticen alimentos nutritivos a la población.
La influencia de la industria alimentaria en la ética del nutriólogo ¿A quién le conviene qué?
Authors: Ceballos Suárez Cristina , Castillo Hernández Karen Geneve
Published: January 2020

Introducción: El capitalismo es un modelo económico que transformó el trabajo artesanal por un trabajo especializado y mecanizado, permitiendo una producción mayor, eliminando a las empresas más pequeñas. La industria alimentaria como parte del sistema tiende a maximizar sus ganancias, utilizando todos sus recursos y contribuyendo a la obesidad, involucrando al profesional de la salud a través de financiamiento de investigación o eventos relacionados con la salud. Objetivo: Indagar y reflexionar en la responsabilidad que como profesionistas se tiene para con la mejora de la salud de la sociedad. Conclusiones: El profesionista de la nutrición, desde los diversos escenarios donde se desempeña es responsable de empoderar a la población para que ésta realice elecciones que beneficien su salud, además de anteponer el bienestar de las personas ante cualquier otro interés.
Windshield Defrost Simplified CFD Model
Authors: Schmid Michal
Published: January 2020

The windshield defrost system, in general, is a vehicle safety feature. Thus, its restricted by variety of directives. However, the OMEs’ benchmark targets could be even more demanding as the deicing process is in addition also part of passengers comfort. From vehicle design point of view the wind-shield defrost system is typically connected to HVAC unit (Heating, Ventilation and Air Conditioning). In the technical solution the windshield is heated via hot air convection. Nevertheless, other methods are becoming more and more popular, like directly heated glass by hot wire ohmic heating (heated glasses). The defrost CFD model should predict the ice layer thickness in time and space and in environmental conditions defined according to appropriate directives and technical solution. The accurate and fast modelling technique is essential part of a vehicle development, especially nowadays, where the optimization techniques area widely used and requires hundreds of simulations runs. Modelling requests are even increasing with modern pure electric vehicles (EVs), were the thermal and energy management is more demanding compared to the classical internal combustion engine (ICE) vehicles. The aim of the work is to verify possibility to model the ice layer thickness with simplified approach, which could be beneficial from computational time burden.
Analysis of the causes of control panel inconsistencies in the gravitational casting process by means of quality management instruments
Authors: Pacana Andrzej , Czerwińska Karolina
Published: January 2020

All castings can have defects caused by, for example, deviations in material characteristics, structure or properties, but the skillful use of available technologies and quality management tools allows for the detection and elimination of casting incompatibilities as well as the prevention of their recurrence in the future. The aim of the article was to analyse the types of defects in castings, locate the areas with the most frequent occurrence of defects and identify the reasons for the presence of defects in castings of the control panel and its cover. The paper presents the usefulness of a combination of quality management instruments for diagnosing material discontinuities in the analyzed castings.
Victorina Durán y Maruja Mallo: encuentros y desencuentros de dos artistas exiliadas
Authors: Gaitán Salinas Carmen , Murga Castro Idoia
Published: January 2020

Nacidas con pocos años de diferencia, Victorina Durán y Maruja Mallo estudiaron en la Escuela Especial de Pintura, Escultura y Grabado, se movieron por el Madrid más moderno, fueron docentes de la Residencia de Señoritas y se dedicaron a las artes plásticas y la escenografía. Con el estallido de la Guerra Civil, ambas se exiliaron a Buenos Aires y trabajaron para Margarita Xirgu, participaron de las Bienales Hispanoamericanas de Arte y expusieron en la Galería Silvagni en París. En Argentina las dos residieron y trabajaron activamente más de dos décadas, antes de retornar a Madrid. Pero, si bien Mallo fue recuperada por el panorama más avanzado de la Movida Madrileña como icono mitificado de aquella cultura prebélica, Durán continuó trabajando en un discreto segundo plano. Este artículo tiene como objetivo analizar los puntos en común en sus trayectorias formativas y profesionales y deducir por qué ambas creadoras nunca colaboraron y apenas se mencionaron en sus escritos.