bluuebunny/crossref_metadata_2025 huggingface dataset:
Facilitators and Barriers to Implementation of Financial Incentive Interventions for Health Behaviour Change: A Systematic Review Protocol
Authors: Lasheen Reham A. , Kavanagh Paul , Doyle Brian , Downey Cheyenne , Siersbaek Rikke , Stanistreet Debbi , Doyle Frank
Published: July 2024

Background Health behaviours, whether protective or harmful in nature, significantly impact health outcomes. Nevertheless, it is recognised that adherence to a healthy lifestyle and enabling behaviour change remains a significant challenge. In efforts to optimise healthcare delivery to ensure positive health outcomes, behavioural economics has provided critical insights on various tools aimed at behaviour change, one of which is financial incentives. However, financial incentive programmes are complex, heterogeneous in design and context-dependant which renders them challenging to implement in real-life settings. Hence, careful consideration to facilitators of and barriers to their implementation to maximise their use is warranted. Aim This study aims to investigate the factors that influence the implementation of financial incentive programmes targeted at any behaviour change in real-life settings, as reported by key stakeholders, to guide future implementation initiatives. We will also conduct a sensitivity analysis comparing smoking to other behaviours, given its significant detrimental impact on health outcomes and its role in widening health disparities. Methods A systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Rapid Review 2020 guidelines, as well as expert recommendations, will be undertaken, to identify stakeholder-reported challenges and enablers of implementation of financial incentive programmes globally. Seven electronic databases, including MEDLINE, EMBASE and CENTRAL, will be searched for papers published from inception to June 2024. A narrative synthesis of the findings will be presented and subsequently mapped to the Theoretical Domains Framework and the Behaviour Change Wheel. Sensitivity analysis comparing findings from smoking studies will be compared to other behaviours. Ethics and dissemination Ethical approval is not required for the review. The protocol and rapid review will be submitted to an open-access peer-reviewed journal for publication. The review findings will allow for the design of effective financial incentive interventions informed by theory, which are adaptable and applicable across various settings.
The genome sequence of the gudgeon, Gobio gobio (Linnaeus, 1758)
Authors: Nunn Andy D. , Moccetti Paolo , Hänfling Bernd ,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: July 2024

We present a genome assembly from an individual female Gobio gobio (the gudgeon; Chordata; Actinopteri; Cypriniformes; Gobionidae). The genome sequence spans 1,460.70 megabases. Most of the assembly is scaffolded into 25 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 16.61 kilobases in length.
The genome sequence of a rove beetle, Lordithon lunulatus (Linnaeus, 1760)
Authors: McCulloch James , Crowley Liam M. ,   University of Oxford and Wytham Woods Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: July 2024

We present a genome assembly from an individual male Lordithon lunulatus (rove beetle; Arthropoda; Insecta; Coleoptera; Staphylinidae). The genome sequence spans 674.40 megabases. Most of the assembly is scaffolded into 10 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 19.26 kilobases in length.
The genome sequence of the harvestman spider, Odiellus spinosus (Bosc, 1792)
Authors: Henriques Sergio ,   Natural History Museum Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: July 2024

We present a genome assembly from an individual female Odiellus spinosus (harvestman spider; Arthropoda; Arachnida; Opiliones; Phalangiidae). The genome sequence spans 443.70 megabases. Most of the assembly is scaffolded into 16 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 16.07 kilobases in length.
The genome sequence of the Maiden’s Blush moth, Cyclophora punctaria (Linnaeus, 1758)
Authors: Broad Gavin R. , Januszczak Inez ,   Natural History Museum Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: July 2024

We present a genome assembly from an individual male Cyclophora punctaria (the Maiden's Blush; Arthropoda; Insecta; Lepidoptera; Geometridae). The genome sequence spans 301.50 megabases. Most of the assembly is scaffolded into 31 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 16.86 kilobases in length. Gene annotation of this assembly on Ensembl identified 16,090 protein-coding genes.
Cocinas Comunitarias para la Inclusión Social en Barrios Desfavorecidos.
Authors: Sianes Antonio , Vela-Jiménez Rocío , López-Montero Rocío , Delgado-Baena Antonio
Published: July 2024

Con origen en los movimientos urbanos “de base” de la década de 1980, las Cocinas Comunitarias son programas que se caracterizan por empoderar a las personas participantes, aumentando su autosuficiencia pero también su dignidad. Por ello, comunmente, entre las actuaciones de inclusión social solicitadas por los vecinos de barrios desfavorecidos, destaca la creación de cocinas comunitarias. El objetivo de esta investigación es analizar las visiones del vecindario de Las Palmeras, en Córdoba (España), sobre las características de una cocina comunitaria para su barrio. Aplicando una metodología de Investigación Acción Participativa se recogen las opiniones de los vecinos mediante debates de grupo. Los resultados aportan matices a la literatura previa, destacando los temores sobre las fórmulas de gestión así como las expectativas de coordinación con las estructuras existentes. La investigación muestra cómo, para las intervenciones en barriadas desfavorecidas es conveniente abrir espacios participativos donde la voz vecinal adquiera centralidad y exprese sus necesidades y cómo abordarlas
Ischaemic colitis from an unusual cause: oral contraceptives
Authors: Colantonio Mark A. , Williams Nathan , Ahmad Tahreem , Ali Waqas
Published: July 2024

Ischaemic colitis is responsible for more than half of the presentations of gastrointestinal ischaemia and develops due to an interruption of intestinal blood flow. Risk factors include increasing age and conditions associated with decreased perfusion. Infrequently, ischaemic colitis may develop in young females prescribed oral contraceptives. Here, we present a case of ischaemic colitis secondary to oral contraceptives that resolved with medication discontinuation.
Whooping cough: An urgent call for greater immunisation uptake
Authors: Lepkowska Dorothy
Published: July 2024

Following a spike in cases of whooping cough in recent months, the UK Health Security Agency is calling for unvaccinated pregnant women and infants to come forward. Dorothy Lepkowska explains
Safeguarding: A public health response
Authors: Gallogly Anne-Marie
Published: July 2024

The publication of the revised Working Together guidance has raised many concerns in the school nursing community, Anne-Marie Gallogly takes us through the changes and offers useful advice.
Variety in carers’ views regarding care responsibilities from an intersectional perspective
Authors: Wittenberg Yvette , Kwekkeboom Rick , de Boer Alice H. , Verhoeff Arnoud P.
Published: July 2024

Challenges in keeping healthcare affordable make informal care increasingly important. It is essential to understand the context in which people provide informal care and gain insight into their wishes with regard to the division of care responsibilities. A total of 37 interviews and eight focus groups were conducted to investigate how Dutch carers’ care attitudes are shaped. Results show that carers’ intersecting social positions, such as gender, migration background, socio-economic status and stage of life, largely influence their care attitudes. Carers want to provide care but experience challenges in doing so. They request a government that takes the lead and facilitates cooperation with professionals.
How Human Rights Became Gay Rights: A History of Toonen v Australia
Authors: Pretsell Douglas , Jones Timothy Willem
Published: July 2024

ABSTRACT: When the Legislative Council of the Australian island state of Tasmania rejected gay law reform in July 1991, a group of enterprising activists took their case to the United Nations. In April 1994, the United Nations Human Rights Committee ruled in their favor. The case, Toonen v Australia , is a landmark human rights judgement that has proved highly influential in the years that have followed. Using interviews with the principal participants, this article provides a historical narrative of their activist journey.
The Agency of Refugees and Asylum-Seeking Women in the Face of the Inability of States to Provide Protection Against Sexual and Gender-Based Violence
Authors: Sarkin Jeremy Julian , Morais Tatiana
Published: July 2024

ABSTRACT: Drawing on fieldwork in Greece, Uganda, and Israel, this empirical study is an enquiry into the forms of agency adopted by refugee and asylum-seeking women who are survivors of, or in situations of risk of, sexual and gender-based violence. The article identifies the main agentic behaviors reported by participants to prevent and address multiple and intersecting discriminations leading to sexual and gender-based violence. It ascertains various types of agency, including passive versus active agency; silence as agency versus silence as oppression; and individual versus collective agency. The study then also asks what functions these forms of agency fulfill. It finds that they are responses to the state’s failure to prevent and address sexual and gender-based violence in four ways: (1) to acknowledge asylum-seekers sufficiently; (2) to protect asylum-seekers from sexual and gender-based violence; (3) to guarantee access to justice to sexual and gender-based violence survivors; and finally (4) to prevent further discrimination of the hosted community. Thus, this article argues that refugees and asylum-seekers adopt different types of agency to react against the state’s inability to provide protection from sexual and gender-based violence.
Women and Intellectual History in the Twentieth Century, Part One: Rethinking the “Origins” of US Intellectual History
Authors: Smith Sophie
Published: July 2024

Abstract: This essay argues that work on the history of women's ideas has been repeatedly written out of the multiple historiographical reviews of twentieth century intellectual history. By recovering that work, and the contexts and sites of its production, the essay offers a new perspective on the historiography of intellectual history in the twentieth century.
Foucault and Dumézil on Antiquity
Authors: Elden Stuart
Published: July 2024

Abstract: The biographical links between Michel Foucault and the comparative mythologist and philologist Georges Dumézil have received more attention than their intellectual connections. This article contributes by surveying Foucault’s engagements, from a 1957 radio lecture to his late lectures at the Collège de France. Particular focus is on lectures on structuralism and history in 1970, some references between 1970 and 1981, and the use of Dumézil’s work in each of Foucault’s two final courses at the Collège de France. In each, Foucault takes up Dumézil’s analyses of mythology in developing his own projects concerning history and antiquity.
Fragments of Splendor: Indonesian Textiles in the Lloyd Cotsen Collection
Authors: Barnes Ruth
Published: July 2024

Abstract: The contribution discusses a representative selection of the Indonesian textiles collected by Lloyd Cotsen, which are now part of the George Washington University Museum and The Textile Museum, and considers them through a historical perspective. Some early radiocarbon dated pieces provide essential evidence that can be reinforced by similar results from collections elsewhere. This provides the chronological framework. Written sources are used as much as possible to add to the historical context. Connections between different Indonesian island cultures, referred to in early documents and oral histories, are also explored to broaden the geographic perspectives. The rich literature on Southeast Asian textiles, developed over the previous three decades, will be a constant and significant reference point, but the essay attempts to move beyond previous research by attempting a deeper historical view.
Polarization-filterless polarization-sensitive polarization-multiplexed phase-shifting self-reference digital holography
Authors: Tahara Tatsuki
Published: July 2024

I propose a phase-shifting self-reference digital holography technique
in which both three-dimensional (3D) and polarization information is
simultaneously obtained without any polarization filters. A
Fourier-transform lens, a polarization beam splitter, and two
phase-only spatial light modulators are used to simultaneously
generate self-reference holograms with orthogonal polarization
directions. 3D and polarization information is multiplexed in the
recorded phase-shifted digital holograms and retrieved by applying
polarization-selective phase-shifting interferometry and numerical
refocusing. The validity of the proposed technique is
experimentally demonstrated.
Heterodyne coherent detection of the electric field temporal trace emitted by frequency-modulated comb lasers
Authors: Chomet Baptiste , Basceken Salim , Gacemi Djamal , Schneider Barbara , Beck Mathias , Vasanelli Angela , Darquié Benoit , Faist Jérôme , Sirtori Carlo
Published: July 2024

Frequency-modulated (FM) combs are produced by mode-locked lasers in which the electric field has a linearly chirped frequency and nearly constant amplitude. This regime of operation occurs naturally in certain laser systems and constitutes a valuable alternative to generate spectra with equidistant modes. Here, we use a low-noise fs-pulse comb as the local oscillator and combine dual comb heterodyne detection with time domain analysis of the multi-heterodyne signal to reveal the temporal trace of both amplitude and phase quadratures of FM comb lasers’ electric field. This technique is applied to both a dense and a harmonic mid-infrared free-running quantum cascade laser frequency comb and shows direct evidence of the FM behavior together with the high degree of coherence of these sources. Our results furnish a deeper insight on the origin of the FM combs and pave the way to further improvement and optimization of these devices.
The evolutionary and molecular history of a chikungunya virus outbreak lineage
Authors: Krambrich Janina , Mihalič Filip , Gaunt Michael W. , Bohlin Jon , Hesson Jenny C. , Lundkvist Åke , de Lamballerie Xavier , Li Cixiu , Shi Weifeng , Pettersson John H.-O.
Published: July 2024

In 2018–2019, Thailand experienced a nationwide spread of chikungunya virus (CHIKV), with approximately 15,000 confirmed cases of disease reported. Here, we investigated the evolutionary and molecular history of the East/Central/South African (ECSA) genotype to determine the origins of the 2018–2019 CHIKV outbreak in Thailand. This was done using newly sequenced clinical samples from travellers returning to Sweden from Thailand in late 2018 and early 2019 and previously published genome sequences. Our phylogeographic analysis showed that before the outbreak in Thailand, the Indian Ocean lineage (IOL) found within the ESCA, had evolved and circulated in East Africa, South Asia, and Southeast Asia for about 15 years. In the first half of 2017, an introduction occurred into Thailand from another South Asian country, most likely Bangladesh, which subsequently developed into a large outbreak in Thailand with export to neighbouring countries. Based on comparative phylogenetic analyses of the complete CHIKV genome and protein modelling, we identified several mutations in the E1/E2 spike complex, such as E1 K211E and E2 V264A, which are highly relevant as they may lead to changes in vector competence, transmission efficiency and pathogenicity of the virus. A number of mutations (E2 G205S, Nsp3 D372E, Nsp2 V793A), that emerged shortly before the outbreak of the virus in Thailand in 2018 may have altered antibody binding and recognition due to their position. This study not only improves our understanding of the factors contributing to the epidemic in Southeast Asia, but also has implications for the development of effective response strategies and the potential development of new vaccines.
Gaps in cancer care in a multi-ethnic population in Sarawak, Borneo: A central referral centre study
Authors: Lim Melissa Siaw Han , Voon Pei Jye , Ali Adibah , Mohamad Fitri Suraya , Jong Lin Lin , Chew Lee Ping , Bujang Mohamad Adam , Augustin Yolanda , Cheng Yuong Kang
Published: July 2024

Background

The state of Sarawak on the island of Borneo in East Malaysia, in working towards developing and strengthening cancer services through a holistic patient-centred approach, must focus on the comprehensive needs of cancer patients by taking into account the psycho-social, cultural and spiritual aspects of Sarawak’s multi-ethnic, multi-cultural population.

Methods

A 42-item survey questionnaire was developed and validated with a total of 443 patients. The perceived importance of information provided and level of patient satisfaction were assessed with a 5-point Likert scale in 10 domains (Diagnosis, Surgery, Radiotherapy, Systemic therapy, Clinical trials, Pain management, Treatment monitoring, Psychosocial support, Sexual care and fertility issues, and Financial support). A Spearman’s rank correlation test was applied to determine the correlation between response in both item and domain categories for perceived importance and satisfaction.

Results

Overall, patients were more satisfied with information related to cancer diagnosis, treatment and surgery but less satisfied with information pertaining to sexual aspects of care and family planning, psycho-social support and financial support. The majority of patients were satisfied with the level of treatment-related information received but preferred the information to be delivered in more easily comprehendible formats. Sexual aspects of care and family planning, psychosocial support and treatment monitoring post-discharge were perceived as important but seldom addressed by health care professionals due to lack of professional counsellors, social workers and clinical nurse specialists. Many patients face financial toxicity following a cancer diagnosis, particularly when diagnosed with advanced cancer requiring complex multi-modality treatment.

Conclusion

Cancer patients in Sarawak have various unmet information needs. Written information and educational videos in local indigenous languages may be more suitable for Sarawak’s multi-ethnic population. Sexual aspects of care and family planning are challenging but essential topics to discuss, in particular due to the high prevalence of breast and cervical cancer amongst young women of reproductive age in Sarawak. Financial assessment and information on support services offered by government and non-government organisations should be provided to eligible patients. A holistic needs assessment of each patient at time of diagnosis and support through their cancer journey requires a multi-disciplinary team of medical, nursing and allied health professionals including clinical nurse specialists, pharmacists, counsellors, physiotherapists, occupational therapists, speech and language therapists, dieticians and social workers.
Study protocol for the Multimodal Approach to Preventing Suicide in Schools (MAPSS) project: A regionally based feasibility trial of an integrated response to suicide risk among UK secondary school pupils
Authors: Ashworth Emma , McCarthy Molly , Wynne Sio , Robinson Jo , McKay Samuel , Lane Steven , Richardson Gerry , Boardman Neil , Henderson Kate , Crosbie Vivienne , Humphrey Neil , York Sian , Michail Maria , Hart Damian , Clacy David , Jalota Mani , Saini Pooja
Published: July 2024

Background

Suicide is the leading cause of death of children and young people under 35 in the UK, and suicide rates are rising in this age group. Schools are considered an appropriate and logical setting for youth suicide prevention activities, with universal, selective, and indicated approaches all demonstrating efficacy. Given that international best practice recommends suicide prevention programmes combine these approaches, and that to date this has not been done in school settings in the UK, this study aims to evaluate the feasibility of delivering a suicide prevention programme incorporating universal, selective, and indicated components in UK schools.

Methods

This study is a feasibility cluster-randomised controlled trial (RCT) of an adapted version of the Multimodal Approach to Preventing Suicide in Schools (MAPSS) programme. The programme, initially developed in Australia, involves delivering universal psychoeducation to all pupils, screening them for suicide risk, and delivering Internet-based Cognitive Behavioural Therapy (Reframe IT-UK) to those students identified as being at high-risk for suicide. The programme will be trialled in six secondary schools in Northwest England and will target Year 10 students (14- and 15-year-olds). The primary aims are to assess: 1) the acceptability and safety of delivering MAPSS in a school setting in the UK; 2) the social validity of the MAPSS programme; and 3) the feasibility of delivering a large-scale, appropriately powered, cluster-RCT and economic evaluation of this intervention in the future. Secondary aims are to assess changes over time in mental health and wellbeing outcomes.

Discussion

This study is the first to evaluate a suicide prevention programme comprising universal, selective, and indicated components in UK schools. If the programme is found to be feasible, it could be more widely tested in schools and may ultimately lead to reduced rates of suicide and suicidal behaviour in young people.
A closely spaced two-port MIMO antenna with a radiation null for out-of-band suppressions for 5G Sub-6 GHz applications
Authors: Rizvi Syed Naheel Raza , Abu Sufian Md , Awan Wahaj Abbas , Choi Young , Hussain Niamat , Kim Nam
Published: July 2024

This paper presents the design and isolation enhancement of a filtering MIMO antenna with a radiation null for out-of-band suppressions suited for 5G sub-6 GHz communications. The MIMO antenna offers -10 dB impedance bandwidth functionality at the most prominent partial spectrum of the 5G NR n78 band for enabling wireless applications in base stations, ranging from 3.4 GHz to 3.61 GHz. To mitigate the redundancy of an RF filter and to achieve a strong filtering response, a radiation null is produced in the gain with four identical rectangular slots, which results in a significant gain drop of more than 8 dBi at the stopband. The geometrical design also allows 30 percent size reduction of single element. Subsequently, a closely spaced (0.11λ0) two-port MIMO antenna is implemented and with the utilization of the proposed rectangular shaped hollow stub parasitic element, the interelement isolation is significantly improved by more than 8 dB over the operational frequency range while retaining the filtering without any additional RF structure. The design simplification, peak gain of 5.4 dBi, near ideal response of diversity gain, ECC less than 0.03, congruency between simulated and measured results, and stable parameters make it a valuable choice for 3.5 GHz sub-6 GHz communications.
Flexibility in conceptual combinations: A neural network model of gradable adjective modification
Authors: Carter Georgia-Ann , Keller Frank , Hoffman Paul
Published: July 2024

Our ability to combine simple constituents into more complex conceptual combinations is a fundamental aspect of cognition. Gradable adjectives (e.g., ‘tall’ and ‘light’) are a critical example of this process, as their meanings vary depending on the noun with which they are combined. For example, a dark diamond is less dark than dark charcoal. Here, we investigate how a neural network encodes the flexible nature of gradable adjectives in adjective–noun pairs, using the perceptual feature of brightness as a test case. We trained a neural network to predict human brightness ratings for unmodified nouns and adjective–noun pairs and assessed its ability to generalize to untrained combinations (e.g., ‘light paint’ vs. ‘dark paint’). We also explored how this information is encoded. We found that flexible learning of gradable adjectives was possible, with neural networks first making predictions based on the adjective alone, and then modulating these with information from the noun later in learning. We also found that model outputs mimicked the kind of non-additive feature modulation present in human data. Our results have implications for understanding how semantic composition occurs and generate testable predictions for future work.
Spatiotemporal dynamics of ecosystem services in response to climate variability in Maze National Park and its environs, southwestern Ethiopia
Authors: Simeon Mestewat , Wana Desalegn , Woldu Zerihun
Published: July 2024

Climate variability is one of the major factors affecting the supply of ecosystem services and the well-being of people who rely on them. Despite the substantial effects of climate variability on ecosystem goods and services, empirical researches on these effects are generally lacking. Thus, this study examines the spatiotemporal impacts of climate variability on selected ecosystem services in Maze National Park and its surroundings, in southwestern Ethiopia. We conducted climate trend and variability analysis by using the Mann-Kendall (MK) trend test, Sen’s slope estimator, and innovative trend analysis (ITA). Relationships among ecosystem services and climate variables were evaluated using Pearson’s correlation coefficient (r), while partial correlation was used to evaluate the relationship among key ecosystem services and potential evapotranspiration (PET). The MK tests show a decreasing trend for both mean annual and main rainy season rainfall, with Sen’s slope (β) = -0.721 and β = -0.1.23, respectively. Whereas, the ITA method depicted a significant increase in the second rainy season rainfall (Slope(s) = 1.487), and the mean annual (s = 0.042), maximum (s = 0.024), and minimum (s = 0.060) temperature. Spatial correlations revealed significant positive relationships between ecosystem services and the mean annual rainfall and Normalized Difference Vegetation Index (NDVI), while negative correlations with the mean annual temperature. Additionally, temporal correlations highlighted positive relationships among key ecosystem services and the main rainy season rainfall. The maximum and minimum temperatures and ecosystem services were negatively correlated; whereas, there was strong negative correlations between annual (r = -0.929), main rainy season (r = -0.990), and second rainy season (r = -0.814) PET and food production. Thus, understanding the spatiotemporal variability of climate and the resulting impacts on ecosystem services helps decision-makers design ecosystem conservation and restoration strategies to increase the potential of the ecosystems to adapt to and mitigate the impacts of climate variability.
Induction of cell death by sodium hexachloroplatinate (IV) in the HEI-OC1 cell line, primary rat spiral ganglion cells and rat organ of Corti explants
Authors: Berger Elisabeth , Brandes Gudrun , Kaiser Odett , Reifenrath Janin , Lenarz Thomas , Wissel Kirsten , Durisin Martin
Published: July 2024

Although cochlear implants have become a well-established method for patients with sensory neural hearing loss, clinical results indicate that in some cases, corrosion of electrode contacts leads to high impedance that interferes with successful stimulation of the auditory nerve. As it is unclear whether corrosion products induce cell damage, we focused on cell culture models of the organ of Corti cell line (HEI-OC1), rat spiral ganglion cells (SGC) and rat organ of Corti explant (OCex) cultivated from neonatal rat cochleae to characterize the cytotoxicity of sodium hexachloroplatinate (IV) (Na2(PtCl6)). The oxidative activity in HEI-OC1 cells decreased with increasing Na2(PtCl6) concentrations between 8 and 16 ng/μl, and live cell staining with Calcein acetoxymethyl/Ethidium homodimer III revealed an increasing number of cells with disrupted membranes. Ultrastructural evidence of mitophagy followed by necroptosis was detected. Additionally, exposure of the SGC to 15–35 ng/μl Na2(PtCl6) dose-dependently reduced neuronal survival and neuritogenesis, as determined by neurofilament antigen staining. In parallel, staining glial cells and fibroblasts with specific antibodies confirmed the dose-dependent induction of cell death by Na2(PtCl6). Exposure of the OCex to 25–45 ng/μl Na2(PtCl6) resulted in severe concentration-dependent hair cell loss. Our data show for the first time that Na2(PtCl6) induces cell death in a concentration-dependent manner in inner ear cell types and tissues.
Effects of using wearable devices to monitoring physical activity in pulmonary rehabilitation programs for chronic respiratory diseases: A systematic review protocol
Authors: Oliveira Thaianne Rangel Agra , Fernandes Ana Tereza do Nascimento Sales Figueiredo , Santino Thayla Amorim , Menescal Fernanda Elizabeth Pereira da Silva , Nogueira Patrícia Angélica de Miranda Silva
Published: July 2024

Introduction

Pulmonary rehabilitation (PR) is an intervention aimed at the comprehensive care of individuals with chronic respiratory diseases. Patients with chronic obstructive pulmonary disease (COPD) and asthma present low levels of physical fitness because they avoid physical exercises due to the fear of triggering recurrent symptoms. Wearable devices have been integrated into behavioral modification interventions for physical activity in PR protocols. Therefore, this review aims to identify how wearable devices are being utilized for monitoring chronic respiratory diseases in pulmonary rehabilitation programs.

Methods and analysis

Searches will be conducted on Medline, Cochrane Central Register of Controlled Trials, Embase (CENTRAL), CINAHL and PEDro electronic databases, as well as a search in the grey literature. We will include baseline data from randomized clinical trials reporting the use of wearable devices for monitoring physical activity in protocols for pulmonary rehabilitation programs for chronic respiratory diseases. Studies that discuss only the development of algorithms or applications for the assessment of diseases or unavailable full texts will be excluded. The main reviewer will conduct the initial search and exclusion of duplicates, while two independent reviewers will select studies, extract data, and assess the methodological quality using the PEDro tool.

PROSPERO registration number

CRD42024504137.
Plant Species for the Manufacture of Malagasy Traditional Alcoholic Beverages
Authors: Randrianarivony Tabita N. , Rakotoarivony Fortunat , Randrianasolo Armand , Hart Robbie
Published: July 2024

Alcoholic beverages are an important component of many traditional events of Madagascar, including life-course events like male circumcision, burial and exhumation. As with many other parts of Malagasy customary practice, these beverages incorporate the unique and richly diverse flora of Madagascar. We conducted structured interviews with producers and consumers of Malagasy Traditional Alcoholic Beverages (MTABs) in 10 regions of Madagascar, spanning the island from east to west and north to south. We documented 75 plant species used to make three types of Malagasy Traditional Alcoholic Beverages: distilled toaka gasy, fermented cane wine betsa, and fermented palm wine trembo. Of the 75 species, 14 were main materials/main ingredients, 55 were additives during fermentation, and six were used as tools for distillation. The species were diverse, occurring in 35 plant families. Particularly species-rich families were Arecaceae (palm family) as main materials and Rutaceae (citrus family) as additives.
Inpatient Gastroenterology Consults Have Little Utility Before Transesophageal Echocardiograms in a Prospective Cohort Study
Authors: Mizrahi Joseph , Marhaba Jade , Paradkar Anika , Klyachman Leslie , Menashe Eyal , Jamorabo Daniel S.
Published: July 2024

INTRODUCTION:

Despite the well-documented safety of transesophageal echocardiograms (TEEs), inpatient gastroenterology (GI) services are called to clear patients for the procedure when they have GI symptoms or comorbidities ranging from mild to clinically significant. We aimed to assess the clinical utility of such consults in preventing TEE complications.

METHODS:

We performed a prospective cohort study of all inpatients at our institution who had a TEE ordered from 7/1/2021 through 7/1/2022. Patients' demographic information, indications for TEE, complications from TEE, 30-day readmission rates, GI team recommendations, and results of any GI-related interventions were collected and analyzed.

RESULTS:

There were 732 patients who had a TEE ordered during our study period, of whom 641 (87.51%) underwent the procedure. Of the 91 (12.49%) who did not have a TEE, none were canceled due to a GI-related concern. There were 23 of 641 patients (3.59%) with complications from the TEE, none of which were GI-related. The GI team was consulted on 36 patients (4.96% of TEEs ordered) and cleared 22 of 36 (61.11%) with no further testing while the remaining 14 of 36 patients (38.89%) underwent workups that were largely normal. Patients who had a GI consult before their TEE had a significantly longer time between their TEE being ordered and the TEE being performed compared with those who did not have a GI consult before their TEE (4.50 days vs 0.77 days, P < 0.01).

DISCUSSION:

Inpatient GI team workups to clear patients for a TEE found no contraindications to TEEs, did not change patient care plans, and led to increased hospital costs and lengths of stay.
Estudos geolinguísticos na Amazônia Legal
Authors: Silva Greize Alves da , Martins Luzineth Rodrigues , Sanches Romário Duarte
Published: July 2024

Nas últimas décadas, tem-se observado um aumento significativo na produção de obras geolinguísticas que abordam os nove estados que compõem a região da Amazônia Legal. Todos esses estados apresentam atlas linguísticos estaduais, concluídos ou em fase de desenvolvimento, além de diversas outras obras mais específicas, voltadas para a descrição dialetal de cidades ou comunidades tradicionais, como apresentam Romano (2014; 2020) e Sanches (2022). Apesar dessa tendência crescente na geolinguística amazônica, muitos desses trabalhos permanecem pouco divulgados e sem a devida publicação. Este estudo tem como objetivo geral apresentar e discutir a produção de atlas linguísticos nesse território, os desafios enfrentados nesse processo e as contribuições dessas obras para a descrição das línguas presentes nesse amplo espaço político. Para alcançar esse objetivo, foi conduzido um levantamento junto aos autores dessas obras por meio de formulário on-line, visando promover discussões e ampliar o diálogo nesse campo. Foi observado que o fazer geolinguístico na Amazônia enfrenta dificuldades intrínsecas à própria realidade do espaço territorial, incluindo as longas distâncias e as dificuldades de acesso às comunidades, especialmente quando o deslocamento fluvial se faz necessário. Além disso, destaca-se a escassez de financiamento para a execução desses trabalhos, o que encarece o processo para os pesquisadores. Essa falta de financiamento também impacta na subsequente publicação dos trabalhos, limitando o acesso a teses ou dissertações às bibliotecas universitárias.
Teatro e educação: o parentesco intelectual entre Paulo Freire e Augusto Boal na luta contra as múltiplas opressões
Authors: Santos André José dos , Ramos Bruna Sola da Silva
Published: July 2024

O presente ensaio baseia-se na investigação sobre as similitudes existentes entre a proposta educativa da Educação Libertadora, de Paulo Reglus Neves Freire, e do Teatro do Oprimido, de Augusto Pinto Boal. Por considerar que as práxis freireana e boaleana apresentam posicionamento ético-político de transformação social, pelo viés da educação e da cultura, consideramos pertinente um estudo que ressalte as aproximações ideológicas entre tais campos de atuação. Com isso, pretendemos construir reflexões acerca do “parentesco intelectual” existente entre esses dois autores, o qual é argumentado em função de suas convergências e complementaridades, com base na apresentação de conceitos que expressam proximidades entre Freire e Boal no que se refere à luta pela reumanização dos seres humanos.
Autorregulação da Aprendizagem na Educação Infantil: Resultados da aplicação de um Plano de Intervenção
Authors: Furtado Maria Roberta Miranda , Ramos Maely Ferreira Holanda , Costa Eliene Baltazar
Published: July 2024

Este artigo tem como objetivo compreender quais as contribuições da autorregulação da aprendizagem para o desenvolvimento cognitivo de crianças em idade pré-escolar por meio de jogos e brincadeiras. Trata-se de um estudo quanti-quali que apresenta a aplicação de um Plano de Intervenção em turmas da Educação Infantil, possuindo como objeto a Autorregulação da Aprendizagem. Aplicado em uma amostra de 120 crianças e 4 professoras, verificou-se a possibilidade de promover a autorregulação da aprendizagem por meio de brincadeiras e jogos e, posteriormente, foram analisadas quantitativamente as avaliações realizadas pelos professores quanto às respostas dos alunos após a intervenção. Os dados foram organizados em grupos indicando o que os alunos conseguiram realizar sem dificuldades, com dificuldade e o que não conseguiram desenvolver. A utilização de brincadeiras e jogos no Projeto foi imprescindível para a realização da pesquisa, os recursos promoveram grande envolvimento das crianças quanto a proposta do estudo.
Narrativas que transformam: a Influência da Abordagem Metodológica de História de Vida de Professores na Construção da Identidade de Licenciandos em Química
Authors: Santana Marlúcia Pereira , Silveira Hélder Eterno da
Published: July 2024

Este trabalho tem por objetivo mostrar como a história de vida de professores de química da educação básica pode influenciar a percepção sobre a docência de estudantes de um curso de licenciatura em química de uma Instituição de Ensino Superior. Para tanto, constroem-se os dados partindo das gravações das aulas da disciplina desse curso de licenciatura que tem como foco a docência em química e de entrevistas feitas pelos estudantes com professores de química do ensino médio. A partir do diálogo com os educadores da educação básica, os licenciandos puderam conhecer os motivos pelos quais escolheram a docência em química e a iniciação na profissão docente. Entende-se que a personalidade docente não “nasce” com a conclusão do curso superior, pelo contrário, é um processo longo, complexo, dinâmico e que exige um esforço individual, mas que dialogue com a sociedade.
Evaluación de un residuo de la combustión de carbón como reemplazo parcial de arena en la producción de ladrillos cerámicos
Authors: Benítez-Vivas José Fernando , Mosquera-Idrobo Luisa Fernanda , Torres-Agredo Janneth
Published: July 2024

Contexto: Durante la combustión de carbón se generan grandes cantidades de residuos, como las cenizas de fondo; éstas se han investigado como reemplazo del cemento y como sustituto de la arena para la producción de concreto. Además, este residuo puede ser usado para la fabricación de productos de arcilla.
Método: En este estudio, se llevó a cabo una caracterización físico-química y mineralógica de las cenizas de fondo; además, se evaluó la toxicidad del residuo a través del test de lixiviación-Procedimiento de Lixiviación Característico de Toxicidad y del ensayo de ecotoxidad-Daphnia pulex. Seguidamente, se fabricaron ladrillos a nivel de laboratorio con adición de cenizas en 2 %, 4 %, 6 % y 8 % con respecto a la cantidad de arena; se evaluaron propiedades físicas y mecánicas y, se realizaron ensayos ambientales a los ladrillos.
Resultados: Los resultados mostraron una reducción de la resistencia a la compresión con el aumento de cenizas; sin embargo, los ladrillos que incorporaron cenizas al 4 % obtuvieron una resistencia de 14,16 MPa el cual cumple con los criterios mínimos de resistencia a la compresión de acuerdo con la norma colombiana para mampostería no estructural. Por otra parte, el ensayo de lixiviación aplicado mostró que las concentraciones de metales lixiviables estaban por debajo de las regulaciones ambientales.
Conclusiones: Estos hallazgos demuestran la viabilidad de utilizar hasta un 4 % de cenizas de fondo de carbón como reemplazante de arena en la producción de ladrillos de arcilla. El cual permitirá mitigar los problemas asociados a su eliminación.
Revalidación de especies del complejo Oxalis laxa (sección Alpinae, Oxalidaceae) que crecen en Chile
Authors: Teillier Sebastián , Concha Rafael , Zuloaga Fernando O.
Published: July 2024

La posición taxonómica de varias especies anuales de la sección Alpinae, afines a O. laxa, ha sido controvertida en recientes publicaciones sobre el género Oxalis. Es así que diversos taxones han sido considerados en la sinonimia de O. laxa o bien eventualmente tratados como válidos o al nivel varietal. En esta contribución se considera correcto incluir a O. micrantha, y otros taxones bajo el concepto de O. laxa, mientras que se concluye que O. campanensis, O. cumingii y O. rigida son especies claramente diferentes de la primera; a la vez se incluyen bajo el concepto de O. laxa a dos variedades de la especie. Los cuatro taxones reconocidos se reconocen e ilustran y se proponen lectotipos para los siguientes nombres: O. dichotomiflora, O. laxa var. minor, O. platycaulis, O. puberula y O. torcana.
Estimación del confort térmico en espacios exteriores: evaluación del periodo frío en Ensenada, Baja California
Authors: Martínez-Bermúdez Elizabeth , Rincón-Martínez Julio César
Published: July 2024

Los estudios del confort térmico en espacios exteriores son fundamentales para favorecer la habitabilidad de los espacios abiertos y mejorar las condiciones de vida de las personas; sin embargo, es necesario que sean producto de las características locales y de las personas del sitio donde se desarrollan los estudios. El objetivo de este trabajo es evaluar la sensación térmica humana durante el periodo frío, con el fin de estimar los rangos de confort térmico para espacios exteriores que permitan ofrecer indicadores de diseño. Para ello, se recabaron observaciones en diversos tipos de espacios abiertos de la ciudad de Ensenada, única en México con clima mediterráneo, con inviernos fríos y húmedos. La evaluación se realizó mediante el enfoque adaptativo y se procesó con el método de Medias por Intervalos de Sensación Térmica (MIST). Se realizó un análisis correlacional respecto a la sensación térmica con las variables climáticas de temperatura del aire, humedad relativa y velocidad de viento. El rango de confort térmico fue de 12,6 ºC a 23,8 ºC, valores por debajo de los rangos anuales estimados para regiones climáticas mediterráneas (21,1 ºC-29,2 ºC y 20 ºC-25 ºC) en el mismo periodo de estudio.
Complejidad y depuración morfológica en experiencias docentes desde la modelación prearquitectural. Eterno retorno de las formas puras
Authors: Cañete-Islas Omar
Published: July 2024

Desde finales del siglo XX se ha ido autonomizando un campo de exploración morfológica en diversas disciplinas y ámbitos de estudio. En el caso de la arquitectura, esta autonomización se ha ido dando sobre la base de una depuración procedimental, incluso algorítmica, que opera sobre una forma depurándola y abstrayendo ciertas cualidades, extendiendo, no sin sucesivas crisis, el paradigma de las formas puras derivado de principios y elaboraciones estéticas propias de la modernidad. Esto ha generado no solo una ampliación de este principio general, sino también otras maneras de aproximarse a él. En cada nueva oleada pareciera que nuevos actos o configuraciones formales son exploradas y agotadas en sus expresiones arquitecturales. Nociones como patrones, pliegues, cubiertas y envolventes morfológicas, crecimientos y fragmentaciones modulares, descomposición o deconstrucción de paneles o piezas, superposiciones, deformaciones, entre tantas otras, solo refuerzan esta tendencia general, entendida como un despliegue depurador del mismo paradigma moderno inicial. En el presente artículo se revisa parte de este desarrollo paradigmático y se exponen parte de las experiencias del autor.
Propuesta metodológica para la identificación de potenciales corredores verdes urbanos. Estudio de caso: Temuco, Chile
Authors: Moreno Roberto , Lora-González Ángel , Galán Carmen , Zamora-Díaz Ricardo
Published: July 2024

Los corredores verdes urbanos son una solución basada en la naturaleza (SBN) que provee zonas de esparcimiento y una red de conectividad urbana para movilidad activa, además de prestar servicios ecosistémicos a los habitantes de las ciudades, que mejoran su calidad de vida, y son una herramienta de gestión fuerte para el desarrollo de ciudades sostenibles. El presente trabajo propone una novedosa metodología, susceptible de ser ampliada, para el diseño de corredores verdes urbanos, mediante un caso práctico en una ciudad de tamaño intermedio, Temuco (Chile), basada en la selección de áreas verdes urbanas pequeño-medianas que unidas a redes de ciclovías y calles peatonales conecten las áreas verdes núcleo de la ciudad, entendiendo estas como zonas verdes de alta densidad y diversidad vegetacional. Los resultados muestran la aplicabilidad de los criterios metodológicos utilizados en el diseño de corredores verdes, y evidencian las condiciones positivas de Temuco respecto a calidad y superficie de áreas verdes, ciclovías y calles peatonales que fomenten la movilidad urbana limpia. Además, el método es replicable en otras ciudades, lo que permite incorporar nuevos parámetros que supongan mayores beneficios provenientes del corredor verde.