bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of the content of postgraduate education of radiologists on the number of diagnostic pitfalls
Authors: Morozov S. Р. , Kvasyuk A. V. , Vetsheva N. N. , Ledikhova N. V. , Kureshova D. N.
Published: February 2019

Background.Question about the quality and format of postgraduate education of doctors raises increasingly in recent years. Development of professional standards and transition to a system of continuing professional education have allowed professional communities to raise issues of the quality of modern education but there is no clear evidence of the dependence of the level of education and the quality of medical care in the accessible literature. Experts of Research and Practical Center of Medical Radiology carried out the identification of dependence of post-graduate education length for radiologists and the quality of their work that can serve as a rationale for amending the system of doctors training.

Patients and methods.The data on education and actual work of 85 radiologists of out-patient and in-patient units of medical organizations of the Moscow Healthcare Department have been analyzed. According to the results of the audit of diagnostic studies, carried out in the “Unified Radiological Information Service” system by the specialists of the Research and Practical Center of Medical Radiology, the final assessment of the work of each radiologist was formed, which reflects the presence or absence of diagnostic discrepancies.

Results.Parameters of diagnostic errors depending on the age of doctors, the general length of service and the length of service as radiologist, the duration of postgraduate education in the clinical specialty and the specialty “radiology” have been compared.As a result of the analysis, it was found that the increase in the proportion of diagnostic differences is directly related to the increase in the age of the doctor and does not depend on either the length of service or the time of work in the specialty. Differences between the groups of physicians with the largest (professional retraining after clinical residency) and the smallest (clinical education + radiology) percentage of clinically significant discrepancies are statistically significant (p = 0.05, at the normative value of the Student's test score of 2.16).

Conclusion.The inverse relationship between the duration of training of the radiologist in the specialty and the proportion of diagnostic errors, which can serve as a significant justification for making proposals for the exclusion of professional retraining within 576 hours for admission to professional activities of radiologists.
Neuroimaging signs of brain lesions in patients with gene-associated microangiopathy (CADASIL)
Authors: Kurochkina N. S. , Moroz A. A. , Konovalov R. N. , Abramycheva N. Yu. , Krotenkova М. V. , Illarioshkin S. N.
Published: February 2019

Purpose. To evaluate specific changes in MRI of the human brain, associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Materials and methods. We enrolled 24 patients with genetically confirmed CADASIL (19–81 y.o.). The following MRI sequences were performed for every subject: T1 MPR, T2, T2-FLAIR, DTI and SWI. Brain tissue lesions were assessed using STandards for ReportIng Vascular changes on nEuroimaging (STRIVE).

Results. In the CADASIL group the following changes were observed (in % of patients): recent small subcortical infarcts – none; lacunes – 54%; white matter hyperintensities (WMH) by Fazekas 1 – 12%, Fazekas 2 – 17%, Fazekas 3 – 71% (sites of predilection: anterior temporal lobe and external capsule); cerebral microbleeds – 42%; enlarged perivascular spaces – 88%; brain atrophy – 27%.

Conclusion. Neuroimaging signs of brain lesions are common for all types of cerebral small vessel disease, including CADASIL. However, there are some features in patients with CADASIL. The detection of petechial intraparenchymal hemorrhages is a diagnostically and prognostically useful marker, so it is very important to use gradient echo planar T2* or SWI sequence in the conventional MRI protocol.
Pitfalls in pancreatic lesion diagnostics: an accessory intrapancreatic spleen
Authors: Tyunibabyan A. I. , Blokhin I. A. , Chernina V. Yu. , Kaldarov A. R. , Karmazanovsky G. G.
Published: February 2019

Introduction. Accessory spleen (splenunculus) is one of the most common benign congenital anomalies in humans. The location of splenunculus may vary from perisplenic, greater omental or mesenterial to intraparenchymal (pancreas, stomach, duodenum, etc.). In the latter case, the additional spleen is called ectopic (from the greekektoposdisplaced). Most frequently detection of such splenic lobules occurs accidentally via abdominal ultrasound.

Objective: two cases of verified intrapancreatic accessory spleen (IPAS) and main criteria for differential diagnosis with other hypervascular pancreatic lesions.

Materials and methods. We present two case reports: a 43-year-old woman with a history of kidney cancer and a healthy 61-year-old man. In both cases, pancreatic neuroendocrine neoplasia (NEN) was initially suspected. Preoperative diagnostics included abdominal ultrasound examination and multiphase dynamic computed tomography (CT) with intravenous bolus nonionic iodine-based contrast agent (native, arterial – 10 sec, venous – 60 sec and delayed – 300 sec after threshold density of 150 HU in the aorta was exceeded). In one case magnetic resonance imaging (MRI) including axial, sagittal and coronal T1and T2-weighted images, diffusion-weighted images and dynamiccontrast-enhanced series with gadolinium chelate was performed. Both patients underwent robotic assisted distal pancreas resection. Morphological examination revealed IPAS.

Results. In contrast-enhanced computed tomography IPAS has densitometric parameters similar to the spleen. Generally, magnetic resonance imaging does not differentiate IPAS, NEN and hypervascular metastases, since all three are generally T2-hyperintense and T1-hypointense. Contrast enhancement pattern with gadolinium chelateswas similar to CT-contrast enhancement pattern.

Conclusion. Intrapancreatic accessory spleen does not require surgical treatment. Therefore, differential diagnosis between IPAS and neuroendocrine neoplasia, solid pseudopapillary tumor and hypervascular pancreatic metastases is crucial. MRI has an advantage with non-invasive diffusionweighted images (DWI). The apparent diffusion coefficient (ADC) of IPAS will be quantitatively similar to the main spleen while other lesion will demonstrate lower ADC values. Scintigraphy with red blood cells bound with 99mTc utilizes the reticuloendothelial system (RES) in the spleen demonstrating characteristic uptake in the IPASand the main spleen. Ultrasound with color Doppler and contrast enhancement may be a good addition to our armamentarium. One can evaluate the vascular pedicle of the IPAS, as well as contrast agent retention in RES via sonography. We believe the multimodal approach including MRI with DWI/ADC to be the most effective.
Application of radiolabeled ligands to the prostate-specific membrane antigen for determine localization of biochemical recurrence of prostate cancer by PET/CT (literature review)
Authors: Leontyev A. V. , Rubtsova N. A. , Khalimon A. I. , Kuliev M. Т. , Pylova I. V. , Lazutina T. N. , Khamadeeva G. F. , Alekseev B. V. , Kostin A. A. , Kaprin A. D.
Published: February 2019

In present days positron emission tomography combined with X-ray computed tomography (PET/CT) is a highly informative, actively developing method of visualization in oncology, and in particular in oncourology. It is widely used to determine the localization of biochemical recurrence (BR) of prostate cancer (PCa). This survey article presents modern trends and prospects of the development of PET visualization of BR of PCa. It shows the diagnostic capabilities of PET/CT with various radiopharmaceuticals, including ligands for prostate-specific membrane antigen (PSMA), their main advantages and disadvantages. Brief historical information, the evolution of radiopharmaceuticals based on ligands to PSMA as the most promising group of radiopharmaceuticals are provided in the article. The biochemical basis of visualization, the main difficulties and possible errors in the interpretation of data, as well as the ways of overcoming them proposed by the researchers are highlighted.
POSSIBILITIES OF CARDIAC MAGNETIC RESONANCE IN SELECTION OF CANDIDATES FOR CARDIAC RESYNCHRONIZATION THERAPY
Authors: Utsumueva M. D. , Mironova N. A. , Kashtanova S. Yu. , Stukalova O. V.
Published: February 2019

Cardiac resynchronization therapy (CRT) is a contemporary and established treatment for patients with symptomatic heart failure, severely impaired left ventricular (LV) systolic dysfunction and a wide (>150 ms) complex. As with any other treatment, the response to CRT is variable. The degree of preimplant scar burden and scar localization to the vicinity of the LV pacing stimulus are known to influence response and outcome. As well as providing measurements of global and segmental cardiac function, coronary venograghy, CMR also permits localization and quantification of myocardial perfusion and scars. This review explores on the role of CMR in the assessment of patients undergoing CRT, with emphasis on risk stratification and RV and LV leads deployment.
SUBTRACTION PULMONARY ANGIOGRAPHY IN DIAGNOSIS OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
Authors: Veselova T. N. , Demchenkova A. Yu. , Martynyuk T. V. , Danilov N. M. , Ternovoy S. K. , Chazova I. E.
Published: February 2019

Purpose. To assess the state of the vascular bed and perfusion of the lungs in patients with chronic thromboembolic pulmonary hypertension (CTEPH) by the method of subtraction computed tomography (CT).Materials and methods. Between November 2015 and May 2018, 65 patients with diagnosis of CTEPH were examined. All patients were examined on a computer tomograph Aquilion ONE 640 VISION Edition (Toshiba Medical Systems) with 320 rows of detectors, slice thickness – 0,5 mm. Assessment of perfusion disorders was carried out using new software, which allows combining contrast and noncontrast images by subtraction. Were analyzed parameters of the parenchyma, blood supply and perfusion status with the calculation of indices of obstruction and perfusion disorders. The obstruction index was compared with the index of perfusion abnormalities, a 6-minute walk test, and mean pulmonary artery pressure according to the right heart catheterization data. Results. The significant correlation was found between the obstruction index and the index of perfusion disorders in patients with CTEPH (r = 0.605; p = 0.000001). Interrelations between vascular-perfusion indices (an obstruction index and an index of perfusion disorders), mean pulmonary artery pressure and distance in a 6-minute walk test were not revealed.Conclusion. Subtraction CT pulmonary angiography allows to assess the severity of vascular lesion and perfusion disorders within a single study, also determine the effectiveness of treatment in patients with CTEPH.
EXPERIENCE OF USING DUAL-ENERGY COMPUTED TOMOGRAPHY IN PATIENT WITH UROLITHIASIS
Authors: Kapanadze L. B. , Serova N. S. , Rudenko V. I. , Aleksandrova K. A.
Published: February 2019

We presented a clinical case of dual-energy computed tomography in a patient with urolithiasis. Was performed a complex evaluation of the specific parameters obtained in dual-energy computed tomography: dual-energy ratio, dual-energy difference, dual-energy index, Z effective and the chemical composition of the urinary stone in a patient in vivo to determine the tactics of surgical treatment and metaphylaxis.
FUNCTIONAL MULTISPIRAL COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF “STRESS” FRACTURES OF THE METATARSAL BONES IN PATIENTS WITH VALGUS DEFORMITY: 2 CASE REPORTS
Authors: Belyaev A. S. , Serova N. S. , Bobrov D. S.
Published: February 2019

“Stress” or “March” fractures is an important question for the traumatologists and radiologists. An important factor in this topic is the timely and qualitative diagnosis of this type of fractures. The choice of the optimal method of diagnosis, reliable visualization of bone-destructive changes significantly affect the tactics of further treatment and the amount of possible surgical intervention. In this article, the authors presents two clinical cases of diagnosis of “marching” fractures.
COMPLEX RADIALOGICAL DIAGNOSTICS IN DRUG-DEPENDENT PATIENTS WITH PHOSPHORUS OSTEONECROSIS OF THE FACIAL SKELETON AT THE PREOPERATIVE STAGE
Authors: Babkova A. A. , Serova N. S. , Medvedev Yu. A. , Pasha S. P.
Published: February 2019

The purpose.To determine the role of complex radiological diagnostics and diagnostic effectiveness of various radiological methods in drug-dependent patients with phosphorous osteonecrosis of the facial skeleton at the preoperative stage.

Materials and methods.The study included 85 drug addicted patients with a diagnosis of toxic phosphorus osteonecrosis of the facial skeleton. In the preoperative period all patients underwent full clinical and radiological examination. Orthopantomography (OPG), skull x-ray, multislice computed tomography (MSCT), cone-beam computed tomography (CBCT) were performed in 85 patients (100%) at the preoperative stage. Also, 19 patients (22.4 %) underwent radionuclide diagnostics, which included planar scintigraphy and single-photon emission computed tomography (SPECT). Further, all patients underwent surgical treatment to the extent of complete or partial resection of the jaws and other bones of the facial skeleton.

Results.According to the data of complex radiological examination at the preoperative stage it was revealed that in 48% (n = 41) cases the osteonecrosis zones were localized in the lower jaw, in 24% (n = 20) in the upper jaw, in 28% (24) patients the pathological process captured both jaws. Also, MSCT and CBCT data revealed the spread of the pathological process to other bones of the facial, in some cases, the brain part of the scull in 25 patients (29.5%). The data of radionuclide diagnostics allowed to reveal the zones of radiopharmaceutical accumulation both in the bones of the skull and outside it. Based on the results of the analysis of the data obtained, the role of complex radiation diagnosis was determined, as well as the diagnostic effectiveness of radiation methods (OPG, X-ray of the skull, MSCT, CBCT) in the examination of drug-dependent patients with phosphoric osteonecrosis of the facial skeleton at the preoperative stage.

Conclusion.The complex radiological diagnostics with application of high informative modern methods (MSCT, CBCT, radionuclide diagnostics) is the required step in the evaluation of patients with osteonecrosis of the facial skeleton at the preoperative stage. The diagnostic efficiency parameters for MSCT were: sensitivity – 98.1%, specificity – 99.6%, the accuracy – 98.8%, for CBCT: sensitivity – 97.3%, specificity – 99.1%, accuracy – 98.4%, for OPG: sensitivity – 78.6%, specificity – 76.3%, accuracy – 77.4%, for radiography of the skull: sensitivity – 61.1%, specificity – 59.2%, accuracy – 60.2%.
MULTIDISCIPLINARY ASPECTS OF THE DIAGNOSIS OF TUBEROUS SCLEROSIS (TWO CLINICAL OBSERVATION)
Authors: Stashuk G. A. , Ignatovic M. Yu. , Shpak O. S. , Denisova L. B.
Published: February 2019

The article describes two cases of quite rare genetic disease, tuberous sclerosis, one of which was diagnosed as early as in adulthood in a patient with a history of episindrom, the other was diagnosed at the age of eleven in a patient with newly diagnosed seizures, having a history of heart rhabdomyoma. Complex use of radiological methods in the conditions of our clinic allowed to establish in short terms the diagnosis, to estimate a condition of internal organs and also to decide on further tactics of treatment and supervision of patients.
Comparative analysis of TI-RADS modifications
Authors: Sich Yu. P. , Fisenko E. P.
Published: February 2019

There is no single classification of TI-RADS. In different countries, various modifications are used. It is necessary to compare different versions of the classification for choosing the most optimal variant.Objective: a comparative “blind” assessment of the thyroid nodules identified by ultrasound, according to the TI-RADS scale in various modifications.Materials and methods. Retrospective analysis of 153 echograms of thyroid lesions: colloid goiter/nodular colloid goiter – 77 observations, autoimmune thyroiditis – 11, follicular adenoma – 77, follicular cancer – 2, medullar cancer – 1, papillary cancer – 36 observations.Results.A comparative evaluation of the reproducibility of the three modifications of TI-RADS was carried out – the opinions of independent experts were homogeneous. Ultrasonic criteria for the evaluation of thyroid nodules for each TI-RADS variant are presented. The European and proposed by Russian authors variants, in addition to the large signs of malignancy, use small features extended in the domestic version of TI-RADS, which increases the sensitivity of these classification options.Тhe shortest time to evaluate thyroid formations was required when using the European classification. The European and proposed by Russian authors variants, in addition to the large signs of malignancy, use small signs, which increases the sensitivity of these classification options until 51 and 53%. The higher sensitivity of the korean variant – 57.8%.Conclusions. It is necessary to further discuss the TI-RADS options and find the most optimal solution.
The role and possibilities of automated breast ultrasound in breast cancer screening in women with high density breast tissue
Authors: Solodky V. A. , Meskich E. V. , Erstein M. A. , Kolesnik A. Yu. , Oksanchuk E. A. , Nudnov N. V.
Published: February 2019

The aim of our study was to improve the diagnosis of breast nodules on a high dense breast tissue. The study involved 280 women with high dense breast tissue (ACR C,D BI-RADS 2015) aged 26 to 83 years (mean age 47.5 years), all women underwent standard digital mammography in two projections and automated breast ultrasound scanning in three projections. The addition of ABUS to mammography in the basic algorithm of the study increases the effectiveness of the diagnosis of nodules: increased sensitivity by 22.9% (MG – 75.9%, MG+ABUS – 98.8%), reduced specificity by 6.95% (MG – 86.7%, MG+ABUS – 79.75%), the added value is 11.25%. The added value of ABUS and HHUS are equal, but the ABUS allows to standardize, store and transmit the data with the possibility of a second reading, as well as to reduce the time of interpretation of the study twice in comparison with HHUS. Thus, ABUS can be used as an additional screening method for women with high dense breast or as the main method of mass examination for young women.
Breast density as a risk factor of development of ductal carcinoma in situ
Authors: Puchkova O. S. , Sinitsyn V. E. , Bogomazova S. Yu. , Mershina E. A. , Shirokiy V. P. , Bazhenova D. A. , Nenaydenko E. V.
Published: February 2019

Objectives. to reveal a potential relationship between the breast density, various radiographic patterns of the breast structure, and the risk of developing ductal adenocarcinoma in situ.Methods.In this study, 169 patients were divided into 2 groups according to the modern X-ray classification L. Tabar. All patients underwent a core biopsy with subsequent histological examination. The first group consisted of 57 women (33.7%) with tumors arising in the terminal ductal-lobular unit – acinar adenocarcinoma (AAB) unifocal and multifocal forms, and the second group – 112 women (66.3%) with types of ductal adenocarcinoma in situ (in situ DAB) and ductal adenocarcinoma in situ associated with the acinar form of breast cancer (DAB + AAB). Pathologic findings on mammography were assessed using the modern classification of L. Tabar. Evaluation of the breast density was made using ACR 2013 classification. The Pattern of radiologic breast structure was evaluated according to the classification of L. Tabar.Results. According to our results, statistically significant differences of the compared groups on the breast density were established (p < 0.001). In the first group, patients with a density of ACR 1 prevailed, the proportion of which was 52.6%. In the second group, the incidence of ACR 4 was highest, with a share of 32.1% among all patients. Thus, it was concluded that there is an association of the breast density ACR 3 and ACR 4 and risk of development of DAB.Conclusions. The high breast density, as well as the IV and V type of the breast structure according to L. Tabar's classification, are statistically associated with an increased risk of developing ductal carcinoma in situ (DAB). Our study also showed a statistically significant difference in the age of onset of ductal and acinar adenocarcinoma of the breast – 52 and 64, respectively.
Coexistence xanthogranulomatous pyelonephritis with renal replacement lipomatosis. Computed tomography. Сlinical case
Authors: Abovich Yu. A. , Afukova O. A. , Yudin A. L.
Published: February 2019

Xanthogranulomatous pyelonephritis is a relatively rare form of chronic pyelonephritis. It is characterized by combination of destructive and proliferative processes with proliferation in the kidney of granulomatous tissue with a large number of lipid-containing macrophages, which are called xanthomous or "foamy" cells. Replacement kidney lipomatosis is also a rare disease that is characterized by proliferation of adipose tissue of the kidney sinus and perirenal adipose tissue with pronounced atrophy of the renal parenchyma. This is the result of renal atrophy, chronic inflammation, nephrolithiasis or long-term current hydronephrosis with the proliferation of adipose tissue in the renal sinus and paranephric fiber. The article presents a case of combining the above-mentioned pathological processes in a patient of the 93-ies. According to clinical manifestations and examination data, xanthogranulomatous pyelonephritis can occur under the guise of pionephrosis, carbuncle, abscess. Deservedly this disease is called "great imitator", because today there are no clear diagnostic criteria, and the diagnosis is established, as a rule, in the postoperative period.
Renal arteriovenous malformations: diagnosis and treatment
Authors: Askerova A. N. , Stepanova Yu. A. , Zotikov A. E. , Ivandaev A. S. , Karmazanovsky G. G.
Published: February 2019

Renal arteriovenous fistula is a comparatively rare malformation that accounts for < 1% of all arteriovenous fistulas malformations. Renal ANM are devided into congenital or acquired, traumatic and nontraumatic, that can cause massive hematuria, pain, retroperitoneal hemorrhage, and heart failure. Non-invasive imaging modalities, including US, MDCT and MRI, are widely used to diagnose this payhology, but the gold standard for the diagnosis of renal AVM remains angiography. The advantage of angiography in comparison with other methods is the possibility of simultaneous treatment of such patients. The treatment of renal AVM can include endovascular dissociation of the arteriovenous fistula or an open operation, including the using of ex vivo techniques. The choice of method of the treatment is based on the general patient status and the characteristics of renal arteriovenous malformation.
X-ray contrast media: focus on safety
Authors: Khokhlov A. L. , Kabanov A. V. , Kozlova O. G.
Published: February 2019

The article presents a modern classification of contrast media, the advantages and disadvantages of radiographic contrast media. The most important adverse events ofcontrast media such as hypersensitivity reactions, thyroid dysfunction andcontrast-induced nephropathy are discussed.
Final Programme - International Ship Control Systems Symposium (iSCSS)
Authors: IMarEST
Published: February 2019

"Inspiring Naval Engineering" - 14th International Naval Engineering Conference and Exhibition incorporating the International Ship Control Systems Symposium (iSCSS). Tuesday 2 – Thursday 4 October 2018 at the Technology and Innovation Centre, University of Strathclyde, Glasgow, UK. INEC/iSCSS 2018 at a glance: Over 300 expert participants; Over 100 peer-reviewed technical papers; The Sir Donald Gosling Award; 15 plus focussed exhibition stands; International attendance from over 18 countries; Excellent networking opportunities and social programme; The relaunch of the International Ship Control Systems Symposium (iSCSS) entitled "Revolutionary Technology Inspiring Ship Control".
Energy efficient propulsion system for dynamic positioning application: design and assessment
Authors: Coraddu A , Donnarumma S , Chu K , Figari M
Published: February 2019

Dynamic positioning systems are most commonly used in offshore operations. They provide an automated controlling of position and heading of the vessel using its own thrusters to compensate environmental disturbances. The allocation of total required force over the available actuators is a complex task, as DP-systems are over-actuated. Therefore, one of the main challenges faced by the industry is constantly seeking to improve the systems efficiency for both sustainability and economic reasons. Furthermore, it is important to evaluate the performance of a DP vessel under critical conditions. In this paper, the authors aim to compare different thrust allocation logics based on the optimisation of different objective functions. Using a simple validation tool, the authors were able to investigate the overall efficiency of a dynamic positioning propulsion system and its ability to operate when a failure occurs.
Morphological and Yield Response of Pulses Against Drought Stress: A Review
Authors: Tahir Aqsa , Qadir Masood , Saif Rabia , Sattar Saira , Tahir Sidra
Published: February 2019

Pulses in Pakistan is used in combination with cereals to balance the diet. Its area and production is decreasing for last many years. In the barren and partly arid regions, water shortage is the major component that restricts yield. Using of drought resistance plant is one of the best ways for good cultivation under drought condition. As the pulses have great nutritional and economical values and drought stress affect their morphological features. The legume yield is mostly cultured in rain fed region of the Punjab where they bear a slighter quantity of water situation resulting in low yield of bean. To overcome these problems it is necessary to get knowledge about the performance of different lines of different pulses crops under water stress conditions. That‘s why in this paper the information about the previous literature has been discussed.
Properties of Flour used in Flat Bread (Gaziantep pita) Production
Authors: Pekmez Hatice
Published: February 2019

Gaziantep pita, one of the regional flat breads in Turkey, had the geographical sign registration certificate in 2017. Gaziantep pita quality is directly related to flour properties. In present study, physico-chemical and flourgraph properties of bread flour containing 0.550% and 0.650% ash content (d.b.) were investigated. Results showed that the moisture contents of both samples were not significantly different from each other and were under upper limit of 14.5%. Sedimentation values for 0.550% and 0.650% ash content (db.) of flours were found good, between 25-36 mL. Wet gluten contents of both flours were determined as medium, between 20-27%. The falling number values for the samples were higher than normal values. The extensibility values were in normal values for both flour samples. The resistance to extension values for both samples were low, although these values were significantly different from each other. Energy value of 0.550% ash content (d.b.) of bread flour was in normal value, while energy value of 0.650% ash content (d.b.) of flour was low. Physico-chemical and flourgraph properties of 0.550% and 0.650% ash content (d.b.) of flours could be improved by blending or adding Î±-amylase.
Use an Organic Biostimulant (Vermicompost Tea) For Enhancement In Vıtro Callus Growth in Sainfoin (Onobrychis viciifolia Scop.)
Authors: Beyaz Ramazan , Hepşen Türkay Fevziye Şüheyda
Published: February 2019

The health and vitality of callus growth is one of the prerequisites for the success of further in vitro studies. This study investigated the efficiency of different percentage (0%, 10%, 20%, 30%, and 40%) of vermicompost tea as an organic substance on in vitro callus growth in sainfoin. Morpho-physiological responses of calli to vermicompost tea measured under in vitro conditions. As a result of this investigation, a combination of plant growth regulators (4 mg/l BAP and 0.5 mg/l NAA) with 20% of vermicompost tea causing significant callus initiation and growth in sainfoin stem explants. Under the light of these scientific findings, vermicompost tea might be used as an organic bio stimulant for efficient callus growth and complementary to commercial chemical hormones in sainfoin. This research is important due to it can contribute positively to the plant species that are difficult in terms of callus growth and plant regeneration in tissue culture.
SIFAT KIMIA TANAH DAN POPULASI KUMBANG TANDUK (Oryctes rhinoceros L.) STADIA PRADEWASA PADA BERBAGAI KEDALAMAN PENEMPATAN TANDAN KOSONG KELAPA SAWIT
Authors: Fauzana Hafiz , Alfasiri Ayubi , Nelvia Nelvia
Published: February 2019

Oil palm is a very significant industrial plant in producing vegetable oils that require high levels of nutrients in its cultivation. Cultivation of oil palm yield can produce industrial waste, the oil palm empty trunks (TKKS) which have the potential to supply nutrients to oil palm land. The placement of empty trunks at various depths is expected can give effect to the population of Oryctes rhinoceros L pre-adult stage and chemical soil properties. This research was conducted on oil palm plantation in PT. Perkebunan Nusantara V Sei Galuh Tapung, Kampar, Riau from July to October 2017. The aim of this research is to examine the effect of empty trunks placement against the Oryctes rhinoceros L population development and chemical soil properties. This research was done using a randomized experiment design complete with the treatment of the depth empty trunks placement (placement of oil palm empty trunks on the ground at the depth of 10 cm, 20 cm, and 30 cm) which is repeated four times. The observed parameters include the population of infestation of Oryctes rhinoceros L (population of eggs, larvae and pupae) and soil chemical properties (soil pH, C-organic, N-total, P-total and K-total). The results showed that empty trunks placed below the surface at various depths affected the Oryctes rhinoceros L population. Placement of TKKS depth in the soil cannot be infested by Oryctes rhinoceros L. Placement of empty trunks at the depth of the soil tends to increase pH (from very acidic categories to acidic categories) and total K (from the low category to very high category), is not effected on C-organic and N-total and can reduce P-total (from the very high category to the high category) if compared to the placement of empty trunks on the ground.Key words : Chemical Soil properties, Oryctes rhinoceros L., Oil palm Empty trunks, Soil depth
HUBUNGAN AKTIVITAS IBU HAMIL DENGAN KEJADIAN PERSALINAN PREMATUR
Authors: Murtiningsih Murtiningsih
Published: February 2019

Prematuritas masih merupakan penyebab terbanyak kedua kematian bayi usia 0-6 hari dengan persentase 34%.   Faktor resiko yang berkontribusi terhadap persalinan prematur diantaranya faktor resiko modifiable. Faktor tersebut yaitu aktivitas fisik. Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik ibu pada saat kehamilan dengan kejadian persalinan prematur. Desain penelitian korelatif dengan pendekatan cross sectional. Sebanyak 27 orang ibu dengan persalinan prematur menjadi responden dengan tehnik accidental sampling. Alat pengumpulan data berupa pedoman wawancara. Hasil analisis univariat didapatkan karakteristik responden pada usia resiko tinggi 48.1%, pendidikan rendah 66.7%, riwayat premature 18.5%, kebiasaan merokok 40.7%, pre eklamsia 40.7%, BMI pra-konsepsi tidak normal 40.7%. Aktivitas ibu hamil berat 33.3% dan  yang mengalami  persalinan prematur berat (<34 mg) 59.3%. Hasil analisis bivariat terdapat hubungan signifikan antara aktivitas fisik ibu pada saat kehamilan dengan kejadian persalinan prematur (p=0,033). Ibu hamil yang beraktivitas berat yaitu berdiri lebih dari 2 jam/hari mempunyai resiko 10 kali lebih tinggi mengalami persalinan prematur berat. Hasil penelitian ini dapat menjadi acuan bagi tenaga kesehatan perlunya meningkatkan pengetahuan tentang faktor yang berkontribusi terhadap kejadian persalinan prematur, yaitu aktivitas selama kehamilan. Tenaga kesehatan dapat memberikan pendidikan kesehatan atau konseling sedini agar ibu hamil melakukan aktivitas ringan selama kehamilannya sehingga persalinan prematur dapat dicegah. Hal ini berkontribusi terhadap penurunan morbiditas dan mortalitas akibat persalinan prematur. Perlu dilakukan penelitian lanjutan dengan cohort atau desain quasi eksperimen tentang pembatasan aktivitas ibu hamil untuk mencegah persalinan prematur.
Flexural Behavior of Reinforced Concrete One-Way Slabs with Different Ratios of Lightweight Coarse Aggregate
Authors: Jomaa’h Muyasser M. , Ahmed Shamsad , Algburi Hussein M.
Published: February 2019

The aim of the present research includes an experimental investigation of flexural behavior of lightweight reinforced concrete one-way slabs with different ratios of course aggregate. Nine lightweight reinforced concrete one- way slabs incorporated by two types of lightweight course aggregate were tested in these investigation. Also the mechanical properties and workability test for concrete used in the study. There was chosen eight concrete mixes were casted by replacing the normal coarse aggregate by lightweight course aggregate; claystone (bonza) and thermostone. Different percentage of aggregate replaced were done (25, 50, 75 and 100) %, in addition to the reference mix of (0%) replacement ratio was casted. For each concrete mix: Three cylinders for compressive strength and density of saturated and dry surface concrete tests, three cylinders for splitting tensile strength test and three prisms for modulus of rupture test were prepared. Also for each mix was casted, prepare a one slab specimen for bending moment test for all mixes contain a light coarse aggregate and reference mix. The main results of mechanical properties are ((38.44-12.38), (3.969-2.172) and (10.467-3.194)) MPa, for compressive, splitting and flexural strength respectively with differences of (67.79, 45.12 and 69.48) % respectively compared with the reference mix. Also the flexural capacities of the lightweight concrete slabs that contained a different ratios of light coarse aggregate (0.028 and 0.026) MPa were recorded with (22.5 and 28.62) % compared with reference sample of 0.035 MPa.
The Geometry of the Catalytic Active Site in [FeFe]-Hydrogenases is Determined by Hydrogen Bonding and Proton Transfer
Authors: Duan Jifu , Mebs Stefan , Senger Moritz , Laun Konstantin , Wittkamp Florian , Heberle Joachim , Happe Thomas , Hofmann Eckhard , Apfel Ulf-Peter , Winkler Martin , Haumann Michael , Stripp Sven T.
Published: February 2019

The H2 conversion and CO inhibition reactivity of nine [FeFe]-hydrogenase constructs with semi-artificial cofactors was studied by in situ and time-resolved infrared spectroscopy, X-ray crystallography, and theoretical methods. Impaired hydrogen turnover and proton transfer as well as characteristic CO inhibition/ reactivation kinetics are assigned to varying degrees of hydrogen-bonding interactions at the active site. We show that the probability to adopt catalytic intermediates is modulated by intramolecular and protein-cofactor interactions that govern structural dynamics at the active site of [FeFe]-hydrogenases.
Место эхоконтролируемых биопсий в диагностике онкологической патологии и маршрутизация пациента при ее выявлении
Authors: Зубов А. Д. , Торба А. В. , Азаб Хусейн
Published: February 2019

Работа выполнена с целью разработки оптимальной последовательности действий, обеспечивающей наиболее полное выявление злокачественных или имеющих риск злокачественности образований при допустимом минимуме диагностических манипуляций. Предложен алгоритм диагностических мероприятий, включающих ультразвуковое исследование и эхоконтролируемую чрескожную биопсию, определяющий роль врача УЗД в установлении показаний и противопоказаний к инвазивной диагностике, на материале 350 пациентов изучена его эффективность. Установлено, что при новообразованиях щитовидной и молочной желез диагностический процесс в 34,0±3,9% случаях не являлся оптимальным, что проявлялось в избыточности или недостаточности эхоконтролируемых диагностических вмешательств, неправильном выборе объекта для биопсии или способа лучевой навигации. Основной причиной выбора неоптимальной диагностической тактики явилось установление показаний к чрескожной биопсии врачом УЗД без консультации профильного специалиста (онколога, маммолога, эндокринолога и пр.). Показано, что применение разработанного алгоритма, отображающего маршрутизацию пациента при выявлении очаговых новообразований, позволяет достоверно избежать указанных ошибок, повысив тем самым качество диагностического процесса.
Предварительные результаты радикального хирургического лечения рака прямой кишки у больных старческого возраста
Authors: Башеев В. Х. , Амджад Аль Давуд , Золотухин С. Э. , Понсе Прадо А. О. , Башеева Л. А. , Булатова М. А. , Паниев Д. С.
Published: February 2019

Цель исследования — улучшение непосредственных, отдаленных и функциональных результатов хирургического лечения больных раком прямой кишки пожилого и старческого возраста.Материал и методы исследования. В исследование включены 312 больных раком прямой кишки старческого возраста обоих полов (75 лет и старше), которые подверглись радикальному лечению в Республиканском онкологическом центре им. профессора Г. В. Бондаря с 1990 по 2015 г. г. Основным способом оперативного вмешательства явилась брюшно-анальная резекция — 229(73,4%), что связано с частой локализацией опухоли в дистальных отделах прямой кишки — ниже 9см от перианальной кожи, а также осложненным течением и выраженной сопутствующей патологией в большинстве случаев. Лишь в 9 (2,9%) наблюдений оперативное вмешательство закончилось формированием колостомы — выполнены операции Гартмана, что обуславливалось наличием выраженного осложненного течения.Результаты. Интраоперационные осложнения отмечены в 16(5,1%), послеоперационные — у 45(14,4%) больных, послеоперационная летальность составила 15 (4,8%), что можно считать удовлетворительным результатом, учитывая тяжесть контингента больных. Для всех стадий радикально оперированных больных 5-летняя выживаемость составила более половины случаев, а средняя продолжительность жизни стремится к 4 годам, что соответствует данным литературы по лечению рака прямой кишки для всех возрастных групп.Заключение. Представленный материал из 312 наблюдений хирургического лечения рака прямой кишки у пациентов пожилого и старческого возраста (старше 75 лет) продемонстрировал обнадеживающие непосредственные и отдаленные результаты использования первично-восстановительных и сфинктерсохраняющих резекций, как основной хирургической тактики лечения данного контингента больных.
Сравнительные клинико-эпидемиологические показатели по меланоме кожи в Луганской Народной Республике за 2015–2017 гг.
Authors: Торба А. В. , Радионов В. Г. , Пищикова О. В. , Дюльгер Л. Б. , Герасимова В. А.
Published: February 2019

Резюме. Проведен анализ заболеваемости меланомой кожи (МК) среди жителей Луганской Народной Республики. Полученные данные свидетельствуют о том, что у мужчин наибольшая заболеваемость была отмечена в возрасте от 65 лет и старше, а у женщин, в возрасте 45–50 лет. За последние три года (2015–2017 гг.) в республике наблюдается снижение на 20% заболеваемости и на 10,7% летальности от МК, что можно объяснить более ранней диагностикой, широким охватом населения профилактическими осмотрами и проведением на догоспитальном этапе постоянного скрининга населения врачами дерматологами республики.
LiVRation: Remote VR live platform with interactive 3D audio-visual service
Authors: Kasuya Takashi , Tsukada Manabu , Komohara Yu , Takasaka Shigeki , Mizuno Takuhiro , Nomura Yoshitaka , Ueda Yuta , Esaki Hiroshi
Published: February 2019

Of late, various audio-visual services based on the internet are being deployed extensively. Among these, object-based audio-visual services are attracting more attention. In 2014, we had established the software defined media (SDM) consortium to investigate object-based and internet-based audio-visual services. Despite the increasing demand and popularity of live concert events, the placement of the microphone and camera limit the free-viewpoint watching of the contents of package media, such as DVDs. In this study, we design and implement an interactive 3D audio-visual service system called LiVRation, with a free-view-listen point. For subjective evaluation, 211 people were made to experience LiVRation and answer a questionnaire, subsequently. In addition, we demonstrated the system in the "Billboard Live Hackasong 2017" hosted by Billboard Japan, and received the first prize, based on the votes of the judges as well as audience.
TIPOLOGI ARSITEKTUR TRADISIONAL GAYO
Authors: Salwin Salwin , A Hendra
Published: February 2019

Arsitektur tradisional adalah arsitektur yang diwariskan secara turun-temurun berkesinambungan dari satu generasi kegenerasi berikutnya. Dengan kondisi saat ini kesinambungan pewarisan arsitektur Tradisional ini hampir pasti tidak lagi dapat berlangsung dan sangat sulit dipertahankan utamanya disebabkan terkikisnya nilai-nilai tradisi oleh gelombang modernisasi. Dengan kondisi seperti ini perlahan-lahan dan pasti akan punah tanpa sempat di inventarisir. Dalam tujuan itu dengan memanfaatkan berbagai sumber yang ada meskipun sangat terbatas melakukan langkah inventarisir, khususnya arsitektur tradisional Gayo. Umumnya data yang didapatkan terbatas hanya menjelaskan mengenai denah umah Gayo dengan beberapa bentuk denah, umah pitu ruang, umah pitu ruang, umah belah bubung/belah rung dan umah time ruang.Pra-penelitian ini adalah langkah awal untuk menuju kepada rekonstruksi kembali berbagai tipologi bangunanbangunan umah gayo yang ada menlakukan dari sumber yang banyak di Karena keterbatasan pranata ilmiah arsitektur tradisional Indonesia banyak yang sudah hilang dan sangat sulit untuk menemukannya kembali arsitektur lokal, setempat, sangat khas, yang dibangun menurut tradisi budaya masyarakat yang bersangkutan.
PAUD Sebagai Sarana Akomodasi Kebutuhan Pendidikan Anak Usia Dini Dengan Pendekatan Arsitektur Perilaku
Authors: Dafrina Armelia
Published: February 2019

Anak adalah potensi utama bagi masa depan suatu bangsa. Mereka tidak hanya sebagai cikal bakal penerus bangsa tetapi juga sebagai individu yang diharapkan memiliki daya saing yang tinggi. Kepribadian dan kualitas individu pada masa dewasa sangat dipengaruhi oleh pengalaman dan pendidikan yang diperoleh pada masa kanak-kanak. Anggapan bahwa pendidikan baru bisa dimulai setelah usia Sekolah Dasar (SD) yaitu pada saat anak berusia 7 tahun. Menurut Penelitian bahwa pada usia 4 tahun pertama, separuh kapasitas kecerdasan manusia sudah terbentuk. Oleh karena itu Sekolah PAUD (Pendidikan Anak Usia Dini) merupakan suatu wadah untuk mengakomodasi mutu pendidikan bagi anak-anak. Dan juga wadah untuk bermain dan belajar dengan didukung fasilitas penunjang yang dibuat sedemikian rupa untuk menunjang perkembangan pendidikan pada diri anak, di mana anak dibiarkan bebas belajar sambil bermain. Sekolah PAUD sebagai sarana pengembangan pendidikan dan kreativitas anak dengan pendekatan arsitektur perilaku adalah sebuah fasilitas bagi anak-anak usia 0-4 tahun pada khususnya dengan menerapkan konsep bermain sambil belajar (recreation learning) yang bertujuan membantu pengembangan diri anak-anak serta pendekatan arsitektur perilaku digunakan sebagai upaya untuk menghasilkan sebuah bangunan yang sesuai dengan sasaran penggunanya, di mana bangunan dirancang berdasarkan perilaku pengguna. Karakteristik anak-anak yang berbeda-beda pada tiap tahap usia menuntut penyelesaian kebutuhan ruang yang berbeda-beda pula. Selain itu, keaktifan anak dalam bermain membutuhkan perhatian khusus, mempengaruhi pula pada bentuk ruang.
ANALISIS MORFOLOGI RUANG KOTA BANDUNG STUDI KASUS: KAWASAN PERUMAHAN CIPAGANTI- BANDUNG UTARA
Authors: Yasmira Ardha
Published: February 2019

Morfologi merupakan sebuah pendekatan dalam memahami bentuk logis sebuah ruang kota dankawasan.Dalam proses perwujudannya, morfologi kota dapat dilihat sebagai evolusi dari sejarah kota masalalu.Kota Bandung sejak lama direncanakan sebagai salah satu pusat kegiatan Pemerintah Hindia Belandapada tahun 1930-an dan Tahun 1980-an urbanisasi mempengaruhi perubahan morfologi kota Bandungsecara drastis, baik dilihat dari struktur, fungsi maupun wajah kotanya.Struktur bentuk kota Bandung dariawal pertumbuhan hingga sekarang berkembang secara planned (era kolonial) dan organic (awalkemerdekaan hingga sekarang).Bandung khususnya bagian utara (kawasan perumahan Cipaganti)mengalami metamorfosa, dari kota tempat peristirahatan para elit Belanda dan para mandor perkebunantempoe doeloe menjadi kota tujuan wisata urban tourism dengan atraksi wisata kuliner, kesejukan alamidataran tinggi, serta pusat belanja (factory outlets)
Kenyamanan Pejalan Kaki Terhadap Pemanfaatan Jalur Pedestrian Di Jalan Jamin Ginting Medan
Authors: Hutagaol Windi Herson Fernando
Published: February 2019

Abstrak Perkembangan kota ditandai dengan pesatnya pembangunan yang merupakan suatu perwujudan dari realitas perkembangan fungsi kegiatan masyarakat kota didalamnya. Tetapi perkembangan kota ini juga berdampak pada menurunnya kualitas dan kuantitas ruang publik. Ruang publik dapat diartikan sebagai ruang milik bersama dan salah satu fungsi kawasan ruang publik adalah sebagai ruang pedestrian. Kawasan jalan Jamin Ginting merupakan kawasan jalan protokol di Kota Medan yang cukup ramai dilalui oleh pengguna jalan, termasuk pejalan kaki. Oleh karena itu, untuk membentuk sebuah ruang pedestrian jalan Jamin Ginting sebagai ruang publik yang nyaman, maka diperlukan studi mengenai kenyamanan pejalan kaki melalui kenyaman fisik dan kenyamanan iklim. Kenyamanan fisik meliputi eksesibilitas, lebar pedestrian, street furniture, vegetasi dan elemen lainnya. Sedangkan kenyamanan iklim meliputi suhu dan kelembaban udara. Hasil dari penelitian menunjukkan bahwa kondisi exsisting dan fasilitas penunjang yang telah tersedia dalam menunjang kenyamanan pengguna pedestrian di Jalan Jamin Ginting masih masuk dalam kategori tidak nyaman. Jika dilihat dari aspek kenyaman iklim, kurangnya peneduh menjadi kendala utama, sedangkan dari aspek kenyaman fisik menjadi kurang nyaman disebabkan oleh banyaknya hambatan-hambatan dari penggunaan badan jalan sebagai parkir kendaraan.
KRISIS IDENTITAS BANGUNAN DI KOTA BANDA ACEH
Authors: Zainuddin Zainuddin
Published: February 2019

Kota di Indonesia sedang memperbaiki proses modernisasi yang tidak menghasilkan keunikan dan meningkatkan khasanah budaya lokalnya. Kota menjadi seragam, bahkan menjadi korban dari majalah. Kota memecahkan degradasi budaya, sedangkan arsitektural bangunannya terlalu banyak menyetujui paham-paham luar dan melepaskan filosofi-filosofi lokal. Memperbaiki struktur ruang kota yang berbeda dan memulihkan pola sosial masyarakat yang lama dipelihara. Oleh karena itu, penelitian ini dilakukan untuk membuktikan krisis identitas bangunan yang telah dimulai melanda kota Banda Aceh dan membuktikan era globalisasi yang tengah gaya bangunan modern dengan identitas bangunan di kota Banda Aceh. Temuan penelitian menunjukkan sebagian besar masyarakat Banda Aceh mulai tahu tentang bangunan kuno / bersejarah di Banda Aceh mulai memfokuskan karena menyebabkan lagi menerjemahkan perkembangan gaya arsitektur modern yang lebih menarik dibahas gaya arsitektur tradisional; bangunan kuno / bersejarah yang jelas-jelas memiliki identitas kota Banda Aceh dibiarkan rusak begitu saja tanpa adanya insiatif dari pihak terkait untuk diterjemahkan; dari hasil survey yang diperoleh dari bangunan kuno / bersejarah di Banda Aceh. Bangunan yang dapat diakses di pergunakan dengan fungsi yang baru dibuat juga membantu untuk tidak menambah bangunan.