bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnóstico microbiológico en neutropenia febril secundaria a quimioterapia por malignidad hematológica: descripción de una cohorte
Authors: García Karen , Londoño Juliana , Villegas Laura , González María , Correa Alejandro
Published: April 2020

Objetivo: describir las características demográficas, clínicas, terapéuticas y microbiológicas de los pacientes con malignidad hematológica en quimioterapia que desarrollan neutropenia febril durante el tratamiento, así como la mortalidad al egreso.

Métodos: estudio de cohorte retrospectivo en pacientes con neoplasia hematológica que desarrollaron neutropenia febril evaluados en un hospital universitario de Medellín.

Resultados: se obtuvieron registros de 110 episodios de neutropenia febril. Media de edad 45 años. En el 55,4% se obtuvo diagnostico microbiológico, la bacteriemia fue documentada en el 83,8% de ellos. Los microorganismos más comunes fueron K. pneumoniae (30%) y E. coli (18%). La resistencia a antibióticos por presencia de BLEE o carbapenemasas en bacilos gram negativos fue del 33%. La mortalidad ocurrió en el 17% de los pacientes. La leucemia linfoide aguda (LLA) y leucemia mieloide aguda (LMA) fueron los diagnósticos de base más prevalentes, el foco clínico más prevalente fue bacteriemia (24,5%).

Conclusión: En nuestra serie de casos, hay diferencias significativas en cuanto al porcentaje de pacientes con bacteriemia, así como en la mortalidad global respecto al resto de cohortes de la región, es necesario desarrollar un nuevo trabajo de investigación que permita aclarar el origen de estas diferencias.
Finding COVID-19 from Chest X-rays using Deep Learning on a Small Dataset
Authors: Hall Lawrence , Goldgof Dmitry , Paul Rahul , Goldgof Gregory M.
Published: April 2020

Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for diagnosis quickly. This paper explores how useful chest X-ray images can be in diagnosing COVID-19 disease. We have obtained 122 chest X-rays of COVID-19 and over 4,000 chest X-rays of viral and bacterial pneumonia. Unfortunately, we missed the fact that the chest X-rays of viral and bacterial pneumonia came from children under 5 years old. So, this work shows that you can tell kids with pneumonia from COVID-19 adult cases which is not anyone's goal. However, data from adult chest X-rays of other causes of lung disease is needed to see if you can tell adult diseases apart.
Assessing the scholar CanMEDS role in residents using critical appraisal techniques
Authors: Kassam Aliya , Donnon Tyrone , Cowan Michele , Todesco Joanne
Published: April 2020

Background: In this brief report, we describe two ways in which we assessed the Scholar CanMEDS role using a method to measure residents’ ability to complete a critical appraisal.  These were incorporated into a modified OSCE format where two stations consisted of 1) critically appraising an article and 2) critiquing an abstract.Method: Residents were invited to participate in the CanMEDS In-Training Exam (CITE) through the Office of Postgraduate Medical Education. Mean scores for the two Scholar stations were calculated using the number of correct responses out of 10. The global score represented the examiner’s overall impression of the resident’s knowledge and effort.  Correlations between scores are also presented between the two Scholar stations and a paired sample t-test comparing the global mean scores of the two stations was also performed.Results: Sixty-three of the 64 residents registered to complete the CanMEDS In-Training Exam including the two Scholar stations.  There were no significant differences between the global scores of the Scholar stations showing that the overall knowledge and effort of the residents was similar across both stations (3.8 vs. 3.5, p = 0.13).  The correlation between the total mean scores of both stations (inter-station reliability) was also non-significant (r = 0.05, p = 0.67).  No significant differences between senior residents and junior residents were detected or between internal medicine residents and non-internal medicine residents.Conclusion: Further testing of these stations is needed and other novel ways of assessing the Scholar role competencies should also be investigated.
PENGEMBANGAN SOP (STANDART OPERATIONAL PROCEDURES) PENYUSUNAN LAPORAN LABA/RUGI PADA USAHA AYAM GEPREK DI MALANG
Authors: Alfriani Risna , Hermawan Hendy
Published: April 2020

This study aims to produce the vision and mission of the Ayam Geprek Dapur Ayu accounting section, the quality policy of the Ayam Geprek Dapur Ayu accounting section, the task description based on the organizational structure of the Ayam Geprek Dapur Ayu and the SOP (Standard Operational Procedure) of the Chicken Geprek Dapur Ayu. The method in this study uses a collaborative model. Researchers modify the quality system to be developed by researchers in accordance with the needs of prospective product users / users by identifying problems, identifying objectives, developing product designs. The results of this study are the SOP (Standard Operational Procedures) of the Profit / Loss Report on the Geprek Dapur Ayu Chicken Business that researchers have proposed to business owners who have been found to be very beneficial in developing the Geprek Dapur Ayu Chicken business going forward.

Keywords: Development of SOP (Standard Operational Procedure), Profit / LossReport, Collaborative Model.
Numerical Prediction of the Flow Structure Inside Components of Industrial Glass Furnace Systems
Authors: Cravero Carlo , De Domenico Davide , Kenfack Franc D. , Leutcha Philippe J.
Published: April 2020

An important aspect in the glass production industry is related to the heat recovery of the combustion gases. It is usually obtained throughout the use of well-tested technologies, such as regenerative towers with refractory material. For an effective heat recovery, a good distribution of the flow rate at the entrance of the chambers is crucial. The use of Computational Fluid Dynamics (CFD) allows the detailed analysis of the gas evolution during the process; the same would be impractical with experimental measurements, due to prohibitive ambient local conditions. The CFD approach during the design phase typically considers CAD geometries without the level of details related to technological features of the actual installed configuration (i.e. sharp edges vs rounded edges). A brand new built furnace has blunt edges in every connection between 3D walls of refractory blocks. The above edges will be rounded by the erosion-corrosion process due to the harsh chemical/mechanical/thermal environmental conditions inside the plant components (i.e. regenerative chambers, connecting ducts, furnace). The purpose of this work is to evaluate the influence of the geometrical details of the CAD (with focus on the edges connecting adjacent walls), due to technological or erosion aspects, on the flow structure in the furnace components.
KINERJA KUALITAS PELAYANAN PERIZINAN GANGGUAN USAHA DI KANTOR PELAYANAN PERIZINAN TERPADU KOTA GORONTALO
Authors: Tabo Sarfan Dj
Published: April 2020

Performance Optimalisasi of aparatur for ever to improve the quality of goodness of aparatur quality and also itself giving of service. In anticipating constraint in Inwrought Peleyanan Permit hence done some step that is maximizing process service of permit to society either from service procedure facet, aparatur, and medium of prasana. According to Gronroos expressing the quality of service cover the Quality of function, Technical quality, Reputation Company. the prima Service will push society follow to participate in course of development.
Do Funcional ao Simbólico. O que pensam os pares do Campo do Design e o que ensinam nas salas de aula.
Authors: Cipiniuk Alberto
Published: April 2020

Este breve artigo em forma de ensaio relata os resultados de uma pesquisa financiada pelo CNPq sobre o porquê da passagem da dimensão funcional para a simbólica entre as instâncias de legitimação do Campo do Design. Empregando as teorias sociais de Marx e Bourdieu, identificamos o que se pode chamar de identidade dos agentes do campo especialmente no âmbito do Departamento de Artes e Design da PUC-Rio, mas que por homologia, pode ser ampliado para a categoria como um todo.
Constraints on the Emission of Gamma-Rays from M31 with HAWC
Authors: Albert A. , Alfaro R. , Alvarez C. , Arteaga-Velázquez J. C. , Arunbabu K. P. , Avila Rojas D. , Ayala Solares H. A. , Belmont-Moreno E. , BenZvi S. Y. , Brisbois C. , Caballero-Mora K. S. , Capistrán T. , Carramiñana A. , Casanova S. , Cotti U. , Cotzomi J. , Coutiño de León S. , De la Fuente E. , de León C. , Dichiara S. , Dingus B. L. , DuVernois M. A. , Engel K. , Espinoza C. , Fleischhack H. , Fraija N. , Galván-Gámez A. , García-Aguilar D. , García-González J. A. , Garfias F. , González M. M. , Goodman J. A. , Harding J. P. , Hernandez S. , Hona B. , Huang D. , Hueyotl-Zahuantitla F. , Hüntemeyer P. , Iriarte A. , Jardin-Blicq A. , Joshi V. , Kieda D. , Lee W. H. , León Vargas H. , Longinotti A. L. , Luis-Raya G. , Malone K. , Marinelli S. S. , Martinez O. , Martinez-Castellanos I. , Martínez-Castro J. , Matthews J. A. , Miranda-Romagnoli P. , Morales-Soto J. A. , Moreno E. , Mostafá M. , Nayerhoda A. , Nellen L. , Newbold M. , Noriega-Papaqui R. , Peisker A. , Pérez-Pérez E. G. , Ren Z. , Rho C. D. , Rosa-González D. , Rosenberg M. , Rubenzahl R. , Salazar H. , Salesa Greus F. , Sandoval A. , Schneider M. , Sinnis G. , Smith A. J. , Springer R. W. , Surajbali P. , Tabachnick E. , Tibolla O. , Tollefson K. , Torres I. , Villaseñor L. , Wood J. , Yapici T. , Zepeda A. , Zhou H.
Published: April 2020

Cosmic rays, along with stellar radiation and magnetic fields, are known to make up a significant fraction of the energy density of galaxies such as the Milky Way. When cosmic rays interact in the interstellar medium, they produce gamma-ray emission which provides an important indication of how the cosmic rays propagate. Gamma-rays from the Andromeda galaxy (M31), located 785 kpc away, provide a unique opportunity to study cosmic-ray acceleration and diffusion in a galaxy with a structure and evolution very similar to the Milky Way. Using 33 months of data from the High Altitude Water Cherenkov Observatory, we search for teraelectronvolt gamma-rays from the galactic plane of M31. We also investigate past and present evidence of galactic activity in M31 by searching for Fermi bubble-like structures above and below the galactic nucleus. No significant gamma-ray emission is observed, so we use the null result to compute upper limits on the energy density of cosmic rays >10 TeV in M31.
Variability of Massive Stars in M31 from the Palomar Transient Factory
Authors: Soraisam Monika D. , Bildsten Lars , Drout Maria R. , Prince Thomas A. , Kupfer Thomas , Masci Frank , Laher Russ R. , Kulkarni Shrinivas R.
Published: April 2020

Using data from the (intermediate) Palomar Transient Factory (iPTF), we characterize the time variability of ≈500 massive stars in M31. Our sample is those stars that are spectrally typed by Massey and collaborators, including Luminous Blue Variables, Wolf–Rayets, and warm and cool supergiants. We use the high-cadence, long-baseline (≈5 yr) data from the iPTF survey, coupled with data-processing tools that model complex features in the light curves. We find widespread photometric (R-band) variability in the upper Hertzsprung Russell diagram (or CMD) with an increasing prevalence of variability with later spectral types. Red stars (V − I > 1.5) exhibit larger amplitude fluctuations than their bluer counterparts. We extract a characteristic variability timescale, t
ch, via wavelet transformations that are sensitive to both continuous and localized fluctuations. Cool supergiants are characterized by longer timescales (>100 days) than the hotter stars. The latter have typical timescales of tens of days but cover a wider range, from our resolution limit of a few days to longer than 100 days. Using a 60 night block of data straddling two nights with a cadence of around 2 minutes, we extracted t
ch in the range 0.1–10 days with amplitudes of a few percent for 13 stars. Though there is broad agreement between the observed variability characteristics in the different parts of the upper CMD with theoretical predictions, detailed comparison requires models with a more comprehensive treatment of the various physical processes operating in these stars, such as pulsation, subsurface convection, and the effect of binary companions.
Dark Matter Distribution of Four Low-z Clusters of Galaxies
Authors: McCleary Jacqueline , dell’Antonio Ian , von der Linden Anja
Published: April 2020

We present here the weak gravitational lensing detection of four nearby galaxy clusters in the southern sky: A2029, A85, A1606, and A2457. The weak lensing detections of A1606 and A2457 are the first in the literature. This work capitalizes on the wide field of view of the Dark Energy Camera at the Cerro Tololo Inter-American Observatory, which we use to obtain deep, multiwavelength imaging of all targets. We publish maps of the clusters’ projected mass distributions and obtain the M
200 of their clusters through Navarro–Frenk–White profile fits to the 2D tangential ellipticity signal.
On the Number of Independent Parameters of Interstellar Extinction Curves
Authors: Zagury Frédéric
Published: April 2020

The number of independent parameters that ultraviolet interstellar extinction curves depend on has never been decisively clarified, yet the issue is critical for the comprehension and modeling of interstellar extinction observations. Cardelli, Clayton, & Mathis (CCM89) concluded that normalized extinction curves rely on only one parameter, but E. Fitzpatrick and others consider this finding at most a first-order approximation favored by uncertainties in measurement. However, the multiparameter fits successively introduced by Fitzpatrick & Massa were intended to give the best possible analytical representation of extinction curves, not to investigate their degrees of freedom. A deeper examination of these fits and of the CCM89 conclusion shows that they do not necessarily conflict. Fitzpatrick & Massa’s parameterization of extinction curves and the large database (nearly 600 directions) published by Krelowski & Strobel are used in this paper to show that, within the precision allowed by the data, E(λ − V) correlates tightly with E(B − V) for all λ within the near-infrared to far-ultraviolet spectrum. This correlation confirms the relationships that led to the CCM89 fit and calls into question the reliability of today’s interstellar dust models, which all need at least seven parameters (reddening included) to fit observed ultraviolet extinction curves.
Gravitational-wave Radiation of Double Degenerates with Extremely Low-mass White Dwarf Companions
Authors: Li Zhenwei , Chen Xuefei , Chen Hai-Liang , Li Jiao , Yu Shenghua , Han Zhanwen
Published: April 2020

Double degenerate (DD) systems are supposed to be significant gravitational-wave (GW) sources for future space-based GW detectors, e.g., the Laser Interferometer Space Antenna (LISA). Recently, one type of DD system with extremely low-mass WD (ELM WD; ≲ 0.30 M
☉) companions was found in the ELM Survey. These companions have very short orbital periods and are therefore important sources for LISA detection. Further, due to the thick envelope of ELM WDs compared with massive WDs (e.g., CO WDs), they are much easier to find through the combination of electromagnetic (EM) and GW observations. In this paper, we first obtain the population of ELM WDs in DDs by considering the detailed evolutionary tracks of ELM WDs and then analyzing the GW radiation of these systems. We found that about 6 × 103 sources could be solely detected by LISA, including ∼2 × 103 chirping sources, and ∼13 (∼107) more sources are expected to be detected by both LISA and the ELM Survey (Gaia).
Sitticine jumping spiders: phylogeny, classification, and chromosomes (Araneae, Salticidae, Sitticini)
Authors: Maddison Wayne P. , Maddison David R. , Derkarabetian Shahan , Hedin Marshal
Published: April 2020

The systematics of sitticine jumping spiders is reviewed, with a focus on the Palearctic and Nearctic regions, in order to revise their generic classification, clarify the species of one region (Canada), and study their chromosomes. A genome-wide molecular phylogeny of 23 sitticine species, using more than 700 loci from the arachnid Ultra-Conserved Element (UCE) probeset, confirms the Neotropical origins of sitticines, whose basal divergence separates thenew subtribeAillutticina (a group of five Neotropical genera) from the subtribe Sitticina (five genera of Eurasia and the Americas). The phylogeny shows that most Eurasian sitticines form a relatively recent and rapid radiation, which we unite into the genusAttulusSimon, 1868, consisting of the subgeneraSitticusSimon, 1901 (seven described species),Attulus(41 described species), andSittilongPrószyński, 2017 (one species). Five species ofAttulusoccur natively in North America, presumably through dispersals back from the Eurasian radiation, but an additional three species were more recently introduced from Eurasia.Attus palustrisPeckham & Peckham, 1883 is considered to be a full synonym ofEuophrys floricolaC. L. Koch, 1837 (not a distinct subspecies).Attus sylvestrisEmerton, 1891 is removed from synonymy and recognized as a senior synonym ofSitticus magnusChamberlin & Ivie, 1944. Thus, the five nativeAttulusin North America areAttulus floricola,A. sylvestris,A. cutleri,A. striatus, andA. finschi. The other sitticines of Canada and the U.S.A. are placed in separate genera, all of which arose from a Neotropical radiation includingJollasSimon, 1901 andTomisF.O.Pickard-Cambridge, 1901: (1)AttinellaBanks, 1905 (A. dorsata,A. concolor,A. juniperi), (2)Tomis(T. welchi), and (3)SittisaxPrószyński, 2017 (S. ranieri). All Neotropical and Caribbean “Sitticus” are transferred to eitherJollas(12 species total) orTomis(14 species).Attinella(three species) andTomisare both removed from synonymy withSitticus; the synonymy ofSitticus cabellensisPrószyński, 1971 withPseudattulus kratochviliCaporiacco, 1947 is restored;PseudattulusCaporiacco, 1947 is synonymized withTomis. Six generic names are newly synonymized withAttulusand one withAttinella. Two Neotropical species are described as new,Jollas cupreussp. nov.andTomis manabitasp. nov.Forty-six new combinations are established and three are restored. Three species synonymies are restored, one is new, and two are rejected. Across this diversity of species is a striking diversification of chromosome complements, with X-autosome fusions occurring at least four times to produce neo-Y sex chromosome systems (X1X2Y and X1X2X3Y), some of which (Sittisax ranieriandS. saxicola) are sufficiently derived as to no longer preserve the simple traces of ancestral X material. The correlated distribution of neo-Y and a base autosome number of 28 suggests that neo-Y origins occurred preferentially in lineages with the presence of an extra pair of autosomes.
Le populisme au pouvoir
Authors: Urbinati Nadia , Borriello Arthur , Jäger Anton , Borriello Arthur
Published: April 2020

Le populisme au pouvoir en Italie attaque les fondements de la démocratie en opposant le peuple juste à ceux qui n’en font pas partie. Mais la démocratie peut se renouveler.
Notre-Dame, un grand livre de pierre
Authors: Nivat Georges
Published: April 2020

Le 15 avril 2019, Notre-Dame est prisonnière des flammes. La littérature montre que la cathédrale, plus qu’un lieu de culte, est un lieu de culture et une leçon de poétique.
L’autre rive
Authors: Rabinovitch Solal
Published: April 2020

Il s’agit d’une lecture minutieuse du texte de Freud. L’apparition de la pulsion de mort y est rapportée aux hypothèses de l’Esquisse et de Pour introduire le narcissisme. Mais il s’agit surtout de démontrer comment le moment de bascule que constitue ce texte est produit par la rencontre de la psychose et du réel qui se trouve sur l’autre rive.
Freud et l’art du classique
Authors: Ruíz Lladó Alejandra
Published: April 2020

Dans Au-delà du principe de plaisir , Freud écrit un récit sur le premier jeu auto-créé de son petit-fils Ernst. Modèle logique du jeu enfantin, plus connu sous le nom de Fort-Da , il a été raconté mille et une fois par des générations d’analystes, chacun essayant d’expliquer la compulsion à la répétition, le passage entre la première et la deuxième topique, la place de la pulsion de mort et l’objection que la clinique fait au principe de plaisir. Interroger la fonction de ce récit dans la transmission de la théorie psychanalytique, implique de repenser la fonction de la fiction, dans son sens le plus large, aussi bien dans l’intervention freudienne que dans le cas de ceux qui, comme nous, se reconnaissent dans sa tradition.
Passe et purloined letter . En hommage à Alain Didier-Weill
Authors: Chaboudez Gisèle
Published: April 2020

Lors de son intervention au séminaire L’insu que sait de l’Une bévue s’aile à mourre , en 1977, Alain Didier-Weill marquait une étape de l’élaboration sur la Passe, telle que Lacan a voulu qu’il en témoigne. En déplier la valeur interprétative nous est l’occasion de lui rendre hommage.
Dans les imaginaires de l’IA
Authors: Kyrou Ariel
Published: April 2020

Du film Her de Spike Jonze à 2001 L’Odyssée de l’espace de Stanley Kubrick, et des androïdes de Philip K. Dick à l’utopie intergalactique de la Culture de l’écrivain Iain M. Banks, il est impossible de comprendre aujourd’hui l’intelligence artificielle sans s’intéresser à ses puissants imaginaires. Ceux-ci, nourrissant bien des fantasmes de la Silicon Valley, sont essentiels à décrypter pour ne pas les subir, voire pour se les approprier et mieux les détourner, en faire des antidotes contre les multinationales du numérique, puis cultiver grâce à eux nos propres machines rebelles de quelque futur.
Quand les arts détournent l’intelligence artificielle
Authors: Zocco Fabien , Kyrou Ariel
Published: April 2020

Dans le sillage de Chris Marker ou de Grégory Chatonsky, de plus en plus d’artistes contemporains pratiquent la réappropriation, le détournement, l’usage critique de l’intelligence artificielle. Grand connaisseur des arts numériques, Fabien Zocco est l’un d’entre eux. Il est l’auteur, avec le réalisateur Gwendal Sartre, d’ Attack The Sun , film dont des dialogues ont été générés par une IA au cours même du tournage qui suit la dérive d’un youtuber californien paraissant sombrer dans une folie de tuerie. L’enjeu : éprouver «  de l’intérieur  » des outils contemporains comme l’IA pour «  escompter ensuite analyser et déconstruire leurs effets  ».
Questionner « l’intelligence » des machines
Authors: Malabou Catherine , Kyrou Ariel
Published: April 2020

La création de « puces synaptiques » qui seraient dotées d’une certaine plasticité ouvre-t-elle la voie à une intelligence artificielle vraiment « intelligente », même si de façon différente des êtres humains ? Ou la nature des avancées de ce type, d’une plasticité à des années lumières de celle du cerveau humain, nous contraignent-elles à beaucoup plus de scepticisme ? Pour la philosophe Catherine Malabou, l’essentiel est de permettre aux deux intelligences, naturelle et artificielle, de s’enrichir l’une l’autre. De ne jamais fermer la voie des possibles, que ce soit par des réflexions philosophiques, des fictions ou des expérimentations.
Restituer = relier, habiter
Authors: Bertho Elara
Published: April 2020

On connaît Felwine Sarr pour la publication de son rapport sur les restitutions d’objets d’arts africains, codirigé avec Béatrice Savoy et paru en 2018. On connaît moins son œuvre poétique, fictionnelle et philosophique. Cet article entend resituer sa réflexion sur la restitution dans une pensée plus vaste sur la relation , où l’objet d’art est entendu comme un « passeur de cultures », ainsi que dans une pensée du lieu, éminemment locale et cosmopolite tout à la fois.
Le développement des compétences des dirigeants d’entreprise de tourisme sportif : le rôle des objets techniques et du processus de genèse instrumentale
Authors: Dubois Fanny
Published: April 2020

La présente étude consiste à apprécier la contribution des objets techniques dans le processus de développement des compétences des dirigeants d’entreprise de loisirs sportifs, leurs seules connaissances leur permettant difficilement de s’adapter aux évolutions rapides d’un environnement complexe (évolutions de la demande des usagers liées à de nouveaux modes de consommation, nouvelles formes de concurrence, etc.). À partir d’une étude de cas, la recherche montre que l’usage et l’appropriation d’outils numérique peuvent être à l’origine de la diversification des compétences des professionnels étudiés, en suscitant une activité réflexive et l’échange de savoirs et savoir-faire hétérogènes.
Accelerated Corneal Cross-linking as an Adjunct Therapy in the Management of Presumed Bacterial Keratitis: A Cohort Study
Authors: Knyazer Boris , Krakauer Yonit , Tailakh Muhammad Abu , Achiron Asaf , Hecht Idan , Lifshitz Tova , Torres-Netto Emilio A. , Hafezi Nikki L. , Hafezi Farhad
Published: April 2020

PURPOSE:

To compare the outcomes of accelerated photoactivated chromophore for keratitis corneal cross-linking (PACK-CXL) as an adjunct treatment for bacterial keratitis (PACK-CXL plus standard antibiotic therapy) for patients receiving only standard antibiotic therapy.

METHODS:

Retrospective cohort study of outcomes of patients with moderate infectious presumed bacterial keratitis (ulcer diameter 2 to 7 mm and stromal depth < 300 µm) were compared before and after initiation of a new treatment protocol of PACK-CXL in addition to standard antibiotic treatment.

RESULTS:

A total of 70 eyes of 70 patients were included: 39 eyes in the PACK-CXL plus antibiotic (PACK-ABX) group and 31 eyes in the antibiotic only (ABX) control group. The PACK-ABX group showed shorter times to complete reepithelialization (9.3 ± 6.0 vs 16.0 ± 12.7 days,
P
= .01) and did not require tectonic emergency keratoplasty (0% versus 19.4%,
P
= .006). The PACK-ABX group also showed a higher percentage of eyes with complete reepithelialization in 6 days or less (46.2% vs 6.5%,
P
< .001) and a trend for shorter hospitalizations (6.3 ± 5.0 vs 8.5 ± 4.5 days,
P
= .06). A multivariate analysis controlling for age showed that PACK-ABX treatment remained significantly associated with early ulcer reepithelialization (odds ratio = 0.09, 95% confidence interval = 0.02 to 0.48,
P
= .005).

CONCLUSIONS:

This study validates previous findings regarding the use of accelerated PACK-CXL in the treatment of bacterial keratitis. Adding PACK-CXL improved clinical outcomes (reducing healing time) when compared to antibiotics alone.

[
J Refract Surg
. 2020;36(4):258–264.]
The Development of 'JEGER' Application Using Android Platform as History Learning Media and Model
Authors: Sulistyo Wahyu Djoko , Lukmanul K Moch. Nurfahrul , Kurniawan Bayu
Published: April 2020

This study aims to describe the development of the 'JEGER' application using android platform to develop a history learning media and model based on historical potential of General Soedirman's guerrilla in Pacitan, Indonesia. This development used three main steps adopted from Borg and Gall's model. The development scheme of the application takes a place as a media and model in history learning. The draft or prototype was validated by experts of learning material and media. The revised results of the validator's suggestion are tested to examine the effectiveness and feasibility. The average evaluation of the five assessment components showed an average of 92%. It means that the application of ‘‘JEGER’’ is very effective and feasible as an innovative and creative media and model for historical learning
Increasing Geographic Literacy through the Development of Computer Supported Collaborative Learning
Authors: Wahyuningtyas Neni , Idris Idris
Published: April 2020

This paper aims to develop computer supported collaborative learning to improve geographic literacy. This study used research and development with the ASSURE model. The results of this development are in the form of basic geography concept modules with 3 videos integrated into e-learning. The media and material validation show that the product developed was very good and worth testing. In addition, the results of media validation by taking into account indicators of attractiveness, efficiency and effectiveness, were declared very good and students were enthusiastic about learning to use this media. This product can be an alternative medium for the 21st century learning environment that applies e-learning in the learning process.
Development of 'Video Bank' Based on Prehistoric Community Life at The Sangiran Site as an Independent Learning Media
Authors: Jati Slamet Sujud Purnawan , Subekti Arif , Sulistyo Wahyu Djoko
Published: April 2020

Accessibility toward archaeological remains is a vital component in the Indonesian prehistoric lesson among students. Unfortunately, those archaeological relics are scattered in various places throughout Indonesia. Resources for prehistoric period both for lecturer and researcher are abundant, with resources being collected both on several museum and preservation center. The purpose of this paper is to provide an innovation of learning media through R&D methodological phase onto Bank of Video on social prehistoric life in Sangiran sites as independent learning media. First step is the exploration to gain primary data and the preparation of video’s plot held in Sangiran, Sragen, Central Java. Second phase is development process to validate the draft and limited experiment, in order to deliver “normal” accomplishment. The last process, since several revisions of previous stages, is implementation of media, which average outcome is >80. It elucidates the effectiveness of Bank of Video as learning media.
Promoting Effects of Computer Scoring on English Learning of College Students
Authors: Liu Siwei
Published: April 2020

In the age of economic globalization, it is important for college students to master such an international language as English. The computer scoring is an effective tool to enhance their ability of English learning. Drawing on theories of formative assessment and structural learning, this paper mainly verifies the promoting effect of computer scoring on English learning among college students. The data were collected through a questionnaire survey, and a case study was carried out on a scoring website for English writing. The results show that: formative assessment and structural learning lay the theoretical basis for computer scoring; college students generally recognize that computer scoring system greatly enhances their ability and enthusiasm of English learning; the target computer scoring system (www.pigai.org) facilitates autonomous learning under teacher supervision, with the functions on student and teacher interfaces. The research findings greatly promote the development of computer scoring and English learning among college students.
An Adaptive Virtual Reality-Based Serious Game for Therapeutic Rehabilitation
Authors: Ferreira Bruno , Menezes Paulo
Published: April 2020

Conventional motor rehabilitation therapies followed by stroke survivors during their recovery process, are typically intense and involve numerous repetitions of task-specific recommended exercises. However, due to the lack of short-term or immediate results, patients tend to lose motivation on the rehabilitation process, and on performing the therapist recommended exercises at home between sessions. The work described in this article proposes to engage the patients with the therapeutic exercises by transforming the latter into specially designed serious games. After an initial evaluation by therapists, a pilot study was conducted on a rehabilitation clinic that showed that this system is adequate for about 75% of the clinical cases treated. The proposed game was globally well-accepted by patients, showing to be motivational and engaging. These promising results lead us to believe that immersive-based games can indeed be a valuable aid for motor rehabilitation therapies.
The Effect of Oxidation Temperature on Activating Commercial Viscose Rayon-Based Carbon Fibers to Make the Activated Carbon Fibers (ACFs)
Authors: Vu Le Hoang , Nguyen Huu Son , Khanh Dang Quoc , Pham Van Cuong , Le Thai Hung
Published: April 2020

In this work, commercial Viscose (cellulosic based precursor) rayon-based carbon fibers were oxidized to make activated carbon fibers (ACFs). Carbon fibers were made from Viscose fibers in carbonization process at 1200°C. The ultimate carbon fibers possessed carbon content above 94 mass% and fiber dimension about 8 mm. These fibers were activated to make ACFs by oxidizing gas such as steam of carbon dioxide. The experiments were conducted at temperature ranged from 800°C to 900°C with carbonic steam’s flow of 3 l.min-1. The vaporous benzene adsorbability of activated carbon fibers was then measured by Mark Bell method. The adsorbability (a) and specific surface area (ABET) of ACFs were determined. The properties of the produced ACFs were investigated and analyzed by SEM and TEM imaging. The results showed that obtained fibers have maximum benzene adsorbability of 4.58 mmol.g-1 and BET surface area reached 1357 m2.g-1. These activated carbon fibers were able to use for toxic chemical prevention equipment.
Synthesis and Luminescent Properties of Europium Doped Zirconia Nanoparticles
Authors: Nguyen Hoang Viet , Pham Van Huan , Pham Vuong Hung
Published: April 2020

This paper reports a tunable luminescence of europium (Eu 3+) doped zirconia (ZrO2) nanoparticles as a function of hydrothermal temperature, europium concentrations, time and pH value. The nano-sized Eu doped ZrO2 (Eu:ZrO2) particle was synthesized by hydrothermal method at the temperature of 200 °C and time up to 48 h. The nano-sized Eu:ZrO2 particles have a diameter of about 10 nm. The luminescent properties of nano-sized Eu:ZrO2 particle was enhanced in the sample when high temperature, high Eu 3+ concentration and prolonging hydrothermal time were used at pH 7. These results suggest the use of Eu:ZrO2 nanoparticles followed by thermal annealing in tuning the luminescence of Eu:ZrO2 nanoparticles which have potential applications as phosphors in solid state lighting.
Microstructure and Mechanical Properties of In Situ Cast Aluminum Based Composites Reinforced with TiC Nano-Particles
Authors: Maziarz Wojciech , Bobrowski Piotr , Wójcik Anna , Bigos Agnieszka , Szymański Łukasz , Kurtyka Paweł , Rylko Natalia , Olejnik Ewa
Published: April 2020

This work concerns microstructure and mechanical properties investigations of aluminum based composite strengthened with the TiC particles being in nanometer size. The composites were fabricated by the casting method combined with in-situ formation of TiC particles. Applying a suitable composition of components and moderators of SHS reaction which occur during casting, it was possible to cast the samples with TiC particles of size of 150 nm and faceted shape. Microstructure investigations using scanning and transmission electron microscopy (SEM and TEM) allowed to identified the distribution of TiC particles and their preferred location in the microstructure of composites. Also the additional precipitates with different size and shape were identified in investigated samples. Significant increase of strength was observed in in-situ cast composites in comparison to Al-1000 alloy mainly due mainly due to coefficient of thermal expansion and elastic modulus mismatch between the reinforcements and the metal matrix, Hall-Pecht relation and also in minority the Orowan effect.
Reciprocal Space Map Measurement of Ceramics Thin Films for Unequal Lattice Change at High Temperature
Authors: Saiki Atsushi , Miwa Shogo , Hashizume Takashi
Published: April 2020

Ceria and zirconia are very important for their thermal, mechanical, and chemical stability, and their thin films have attracted much attention for applications such as buffer layers for growing electric devices, thermal-shield or optical coatings, corrosion-resistant coatings, oxygen sensors and ionic conductors for fuel cells. To investigate and control the thin film orientation and phase is important to improve those performances. In this study, the reciprocal space maps of CeO2/YSZ/Si(001) were obtained at high temperature by adding a heater to the sample stage. CeO2 and YSZ thin films were epitaxially grown samples. By measuring lattice constants at high temperature, it was conducted that axes of CeO2 and YSZ thin films parallel to the substrate surface showed smaller thermal coefficients than bulk reference and axes perpendicular to the surface showed larger thermal coefficients due to the underlayer and Si substrate. The distortion rate of the lattice of each film was small around at the film deposition temperature. And it could be controled the lattice parameter at the film surface by the film thickness. Therefore, when another thin film, for example, SrTiO3 is deposited on the CeO2 layer, the lattice change of CeO2 with increasing temperature may differ from that before depositing the top layer.
In Situ EBSD Observation of Pearlite-Austenite Reverse Transformation in Eutectoid Steel
Authors: Pham Anh Hoang , Morito Shigekazu , Ohba Takuya , Hayashi Taisuke
Published: April 2020

The reverse transformation of austenite from pearlite was observed in-situ by using a sophisticated EBSD system. Quantitative information on the nucleation sites and orientation selection of the austenite was obtained. Initially, the nucleation sites were restricted to high-angle grain boundary (HAB) and all the austenite orientations were selected by Kurdjumov-Sachs (K-S) orientation relationship. Latterly, the constraints were relaxed as new nucleation sites were involved. The γ growth was preferentially into the pearlite grains without K-S relation. Nucleation and growth at HAB edge may contribute to γ coarse grains, whereas nucleation at pre-existing γ boundary is important to grain refinement of γ structure.
Effect of Heat Treatments on Wettability of Nacre
Authors: Anshar Andi Muhammad , Kobayashi Sengo , Okano Satoshi
Published: April 2020

The surface wettability of biomaterials influences on osteoblast behavior and bone formation. In this research, the variation of wettability of nacre by heat treatments was examined. Plates of the nacre were fabricated from shells of the Akoya pearl oyster. The specimens were heated at 100, 200, 300, 400, 500, and 600 °C. Characterizations of the specimens during and after heat treatments were carried out using scanning electron microscopy, X-ray diffractometry, and thermogravimetry-differential thermal analysis. The water contact angle (WCA) of the specimen was measured to evaluate wettability. The color of nacre changed from iridescent color to brownish weak-iridescence by the heating at and over 300 °C. The nacre heated at and over 300 °C became brittle because organic substances in nacre, which acts as the glue between the aragonite platelets were evaporated by the heating. The WCA of the specimen was decreased with increasing heating temperature, which should be related to the decrease in the number of organic substances in nacre by the heating.
T Follicular Helper Cells Regulate Humoral Response for Host Protection against Intestinal Citrobacter rodentium Infection
Authors: Bai Xue , Chi Xinxin , Qiao Qin , Xie Shan , Wan Siyuan , Ni Lu , Wang Pengzhi , Jin Wei , Dong Chen
Published: April 2020

Citrobacter rodentium colonizes at the colon and causes mucosal inflammation in mice. Previous studies have revealed the importance of the innate and adaptive immune response for controlling C. rodentium infection. In the present study, we examined the role of T follicular helper (Tfh) cells in intestinal C. rodentium infection using mice with Bcl6 deficiency in T cells. Tfh cells were absolutely required at the late, but not the early, phase to control infection. Compared with control mice, we observed systemic pathogen dissemination and more severe colitis in Tfh-deficient mice. Furthermore, the susceptibility of Tfh-deficient mice correlated with an impaired serum IgG1 response to infection, and serum Abs from infected wild-type mice protected Tfh-deficient mice from infection. The transfer of wild-type Tfh cells also restored the levels of IgG1 and led to effective clearance of the pathogens in Tfh-deficient mice. Moreover, during C. rodentium infection, IL-21– and IL-4–producing Tfh cells were increased obviously in wild-type mice, correlating with IgG1 as the major isotype in germinal center B cells. Taken together, our work highlights the requirement and the function of Tfh cells in regulating humoral response for the host protection against C. rodentium infection.
Intubation and mechanical ventilation of patients with COVID-19: what should we tell them?
Authors: Zareifopoulos Nicholas , Lagadinou Maria , Karela Anastasia , Karantzogiannis Gerasimos , Velissaris Dimitrios
Published: April 2020

Severe COVID-19 illness is characterised by the development of Acute Respiratory Distress Syndrome (ARDS), for which the mainstay of treatment is represented by mechanical ventilation. Mortality associated with ARDS due to other causes is in the range of 40-60%, but currently available data are not yet sufficient to draw safe conclusions on the prognosis of COVID-19 patients who require mechanical ventilation. Based on data from cohorts of the related coronavirus-associated illnesses, that is to say Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), prognosis would seem to be worse than ARDS due to other causes such as trauma and other infections. Discussion of prognosis is central to obtaining informed consent for intubation, but in the absence of definitive data it is not clear exactly what this discussion should entail.
Current Clinical Concepts: Conservative Management of Achilles Tendinopathy
Authors: Silbernagel Karin Grävare , Hanlon Shawn , Sprague Andrew
Published: April 2020

Achilles tendinopathy is a painful overuse injury that is extremely common in athletes, especially those who participate in running and jumping sports. In addition to pain, Achilles tendinopathy is accompanied by alterations in the tendon's structure and mechanical properties, altered lower extremity function, and fear of movement. Cumulatively, these impairments limit sport participation and performance. A thorough evaluation and comprehensive treatment plan, centered on progressive tendon loading, is required to ensure full recovery of tendon health and to minimize the risk of reinjury. In this review, we will provide an update on the evidence-based evaluation, outcome assessment, treatment, and return-to-sport planning for Achilles tendinopathy. Furthermore, we will provide the strength of evidence for these recommendations using the Strength of Recommendation Taxonomy system.
Surveillance and Black Box for Car
Authors: B R Gagana , H T Chethana
Published: April 2020

In recent years vehicle accident has become one of the most important problems in almost all over the globe. Drunk and drive, riding without adequate sleep and riding a car at faster speeds are the three significant reasons which lead to drastic increase in the number of accidents. Evidence Collection Car is a device used to record the driving history. This device is installed in a car which stores the readings of engine temperature, detection of obstacle and condition of seat belt. The snapshots inside a car and readings of engine temperature, detection of obstacle and condition of seat belt are collected. The collected information is notified through GSM to the concerned authorities. As a result rescue team will be informed automatically so that injured person will be assisted in a short span of time. The main aim of this paper is to reduce the percentage of road accidents occurring in real time.
Variability in phytoplankton community structure and influence on stabilization pond functioning
Authors: D'Alessandro Emmanuel Bezerra , Nogueira Ina De Souza , Hoffmann Nora Katia Saavedra del Aguila
Published: April 2020

Density of phytoplankton in stabilization ponds influences treatment performance. The study hypothesized that the phytoplankton community structure varies according to local and temporal changes and consequently influences the treatment of the effluent. Phytoplankton community structure in facultative and maturation ponds in central Brazil was analyzed to provide guidance on system operation and maintenance. Further, species density, abundance, diversity, richness, dominance and beta diversity were measured. The efficiency of the treatment was evaluated based on Biochemical Oxygen Demand (BOD). Additionally, a Canonical Correspondence Analysis (CCA) was used to investigate how physical and chemical variables influenced the composition of the most abundant species in the dry and rainy seasons and the microalgae that were most related to the removal of BOD. One hundred and sixty-eight taxa were recorded, and the most abundant classes in both ponds were Chlorophyceae and Cyanophyceae (40% potentially toxic). The maturation pond had greater adaptability in the rainy season, while the facultative pond was more flexible in the dry season. The best period of growth varied among species. In both ponds, Chlorella minutissima was the one which most contributed to the optimization of the treatment. Thus, identifying phytoplankton species and relating them to water quality parameters and weather can help to understand the ecological dynamics of wastewater treatment and provide useful information for the operation and maintenance of stabilization ponds.
Comparison of optimal estimation HDO∕H2O retrievals from AIRS with ORACLES measurements
Authors: Herman Robert L. , Worden John , Noone David , Henze Dean , Bowman Kevin , Cady-Pereira Karen , Payne Vivienne H. , Kulawik Susan S. , Fu Dejian
Published: April 2020

Abstract. In this paper we evaluate new retrievals of the deuterium content of water
vapor from the Aqua Atmospheric InfraRed Sounder (AIRS), with aircraft
measurements of HDO and H2O from the ObseRvations of Aerosols above
Clouds and their intEractionS (ORACLES) field mission. Single-footprint AIRS
radiances are processed with an optimal estimation algorithm that provides
vertical profiles of the HDO∕H2O ratio, characterized uncertainties
and instrument operators (i.e., averaging kernel matrix). These retrievals
are compared to vertical profiles of the HDO∕H2O ratio from the Oregon
State University Water Isotope Spectrometer for Precipitation and
Entrainment Research (WISPER) on the ORACLES NASA P-3B Orion aircraft.
Measurements were taken over the southeastern Atlantic Ocean from 31 August to
25 September 2016. HDO∕H2O is commonly reported in δD notation,
which is the fractional deviation of the HDO∕H2O ratio from the
standard reference ratio. For collocated measurements, the satellite
instrument operator (averaging kernels and a priori constraint) is applied
to the aircraft profile measurements. We find that AIRS δD bias
relative to the aircraft is well within the estimated measurement
uncertainty. In the lower troposphere, 1000 to 800 hPa, AIRS δD bias
is −6.6 ‰ and the root-mean-square (rms) deviation is
20.9 ‰, consistent with the calculated uncertainty of
19.1 ‰. In the mid-troposphere, 800 to 500 hPa, AIRS
δD bias is −6.8 ‰ and rms
44.9 ‰, comparable to the calculated uncertainty of
25.8 ‰.