bluuebunny/crossref_metadata_2025 huggingface dataset:
The value of contrast-enhanced ultrasound and magnetic resonance imaging in the diagnosis of bladder cancer
Authors: Li Cheng , Gu Zhuoran , Ni Peiqian , Zhang Wentao , Yang Fuhan , Li Wei , Yao Xudong , Chen Yifan
Published: March 2023

Objective:

Imaging examination, tumor marker detection, bladder biopsy, and other methods are the common methods for the diagnosis of bladder cancer (BC). This study was aimed to assess the value of contrast-enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) in the diagnosis of BC.

Materials and Methods:

Fifty-nine patients with BC were recruited in our hospital from September 2012 to December 2015, who had CEUS and magnetic resonance diffusion-weighted imaging (MRI + DWI). All patients underwent surgical treatment and definite pathological stage. The series and parallel combined diagnosis methods were applied to calculate the diagnostic sensitivity, specificity, and accuracy through using quantitative apparent diffusion coefficient (ADC) and receiver operating characteristic curve.

Results:

The accuracies of CEUS and MRI + DWI examination for T staging of BC were 74.6% and 76.3%, respectively. Compared with the single diagnostic methods, the two combined diagnosis accuracy was 91.5%, which was significantly improved in diagnosis accuracy (P < 0.05). The diagnostic accuracies of CEUS, MRI + DWI, and ADC for muscle invasion of BC were 81.4%, 83.1%, and 84.7%, respectively. The diagnostic accuracy of CEUS parallel combined with MRI + DWI (91.5%) was obviously enhanced, compared with that with the single diagnostic method.

Conclusion:

The accuracy of CEUS and MRI + DWI combined diagnosis was higher than that with the single diagnostic method. CEUS and MRI + DWI combined diagnosis was a feasible and effective method for the clinical diagnosis of BC.
Efficacy and safety of transcatheter arterial chemoembolization plus hepatic arterial infusion chemotherapy in the treatment of advanced hepatocellular carcinoma with portal vein tumor thrombosis in the main trunk
Authors: Wu Zhiqiang , Gao Jian , Zhuang Wenquan , Yang Jianyong , Guo Wenbo
Published: March 2023

Background:

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the sixth most prevalent malignancy worldwide. The incidence of portal vein tumor thrombosis (PVTT) is recorded as high as 10%–60% in HCC patients. The purpose of this study was to assess the efficacy and safety of transcatheter arterial chemoembolization (TACE) plus hepatic arterial infusion chemotherapy (HAIC) in advanced HCC patients complicated with PVTT in the main trunk.

Patients and Methods:

A total of 33 HCC patients were treated with TACE + HAIC or TACE, respectively. The primary endpoint was overall survival (OS), while the secondary endpoints included progression-free survival, objective response rate (ORR), and disease control rate (DCR) of HCC lesions and PVTT in the trunk. Adverse events and main complications were also investigated. A COX model was used to identify the risk factors associated with OS.

Results:

There were 16 patients receiving TACE + HAIC and 17 receiving TACE. The median OS was longer in the TACE + HAIC group than the TACE group (P < 0.05). There were no significant differences in the ORR and DCR of HCC lesions and PVTT response between the two groups (P > 0.05). Alpha-fetoprotein was <400 ng/ml. Multivariate analysis showed that cavernous transformation of portal vein was associated with longer OS. In terms of complications, the addition of HAIC showed more myelosuppression than the TACE alone group (P < 0.05).

Conclusion:

Compared with TACE alone, HAIC + TACE may be more safe and provide more benefits for HCC patients complicated with PVTT in the trunk.
Synergistic effect of growth factor receptor-bound protein 2/epidermal growth factor receptor dual-targeting peptide inhibitor and salinomycin on osteosarcoma
Authors: Yu Zuochong , Xu Yanlong , Du Longhai , Zhang Fan , Shao Minghao , Xie Lin , Cai Guoping , Lyu Feizhou
Published: March 2023

Context:

The growth factor receptor-bound protein 2 (Grb2)-Sos1 interaction, mediated by modular domains, plays an essential role in the oncogenic MAPK signaling pathway in osteosarcoma (OS). Recently, a dual-targeting peptide that targets the epidermal growth factor receptor and Grb2-Src homology 3 domain in OS cells was designed and synthesized.

Aims:

We investigated the synergistic effects of the peptide and salinomycin (Sal), a chemotherapeutic drug with effective anti-OS properties in clinical therapy.

Subjects and Methods:

Flow cytometry was used to measure the targeting efficacy of the peptide. Migration and CCK-8 assays were used to explore whether Sal and the peptide could synergistically inhibit OS cell behavior. Western blotting was used to detect apoptosis.

Statistical Analysis Used:

Data were analyzed using the GraphPad Prism 5.01. Statistical analysis was performed using the Student's t-test for the direct comparisons and one-way analysis of variance for the comparisons among the multiple groups. Statistical significance was set at P < 0.05.

Results:

The peptide was shown to target OS cells. When applied together, Sal and the peptide synergistically inhibited OS cell migration, invasion, and proliferation through the inhibition of Grb2-Sos1. This synergistic treatment also promoted the apoptosis of OS cells and inhibited tumor volume in vivo.

Conclusions:

These data provide valuable insights into the molecular mechanisms of OS and may be beneficial in clinical therapy.
Golgi phosphoprotein 3 promotes ovarian cancer progression and is associated with cisplatin resistance
Authors: Liu Teng , Jin Zhen-Wei , Li Ying , Zhang Ge , Yang Xiao-Ying , Xu Xiao-Meng , Ma Ying-Chun
Published: March 2023

Background:

Golgi phosphoprotein-3 (GOLPH 3) is involved in the development of several human cancers. However, the clinical significance and biological role of GOLPH 3 in ovarian cancer (OC) remains unknown.

Methods:

The expression of GOLPH 3 in OC cell lines was quantified using real-time quantitative polymerase chain reaction (RT-qPCR) and western blot assays. The role of GOLPH 3 in tumorigenicity, migration, and invasion of OC cell lines by small interference RNA, scratch wound-healing assays, and transwell assays was detected. In addition, western blotting was used to determine whether GOLPH 3 is associated with the PI3K/AKT/mTOR signaling pathway. Furthermore, RT-qPCR verified whether GOLPH 3 is associated with drug resistance.

Results:

GOLPH 3-positive expression rate was higher in OC. Downregulation of GOLPH 3 markedly inhibited the migration and invasion and may be related to the PI3K/AKT/mTOR signal pathway. Moreover, the result of the experiment proved that GOLPH 3 enhances the sensitivity of OC to cisplatin by regulating ATP7A/B. GOLPH 3 promoted the invasion and migration of OC, and the mechanism may be related to the PI3K/Akt/mTOR pathway. In addition, inhibition of GOLPH 3 increased the sensitivity of OC cells to cisplatin, which may be associated with ATP7A/B.

Conclusion:

This study found that GOLPH3 may promote the migration and invasion of OC cells through PI3K/Akt/mTOR pathway. At the same time, low expression of GOLPH3 increased the sensitivity of OC cells to cisplatin.
Elevated β-catenin and C-myc promote malignancy, relapse, and indicate poor prognosis in patients with relapsed glioma
Authors: Yu Xuejuan , Xiao Fengxia , Wei Yuzhen , Miao Lifeng , Zhang Wei , Zhang Xin , Wang Dexiang
Published: March 2023

Context:

Extensive studies have shown that β-catenin and C-myc have been linked to a number of human cancers. However, the role of β-catenin and C-myc in relapse glioma remains unclear.

Aims:

The aims of this study were to investigate the role of β-catenin and C-myc in relapsed glioma patients and to explore the possible impact of malignancy, relapse, and prognosis.

Materials and Methods:

We collected surgical samples of 100 patients with primary and relapsed glioma treated at our institution. Immunohistochemistry (IHC) staining was used to evaluate the expressions of β-catenin and C-myc. The impact of the differences on disease-free interval (DFI), initial overall survival (iOS), and overall survival from the time of glioma relapse (rOS) of the patients was analyzed. Kaplan–Meier survival functions were used to plot survival time, and a log-rank test was used for analyzing statistical significance. Cox multivariate regression analysis was used to determine independent prognostic parameters.

Results:

Compared to primary tumors, relapsed gliomas had higher expressions of β-catenin and C-myc (P < 0.05). Furthermore, the expressions of β-catenin and C-myc were significantly correlated with glioma grade (P < 0.05). These changes in expression at the time of relapse were independent of radiotherapy use. In multivariate Cox analysis, we found that β-catenin and C-myc were independent prognostic factors for rOS (P < 0.05).

Conclusions:

Elevated β-catenin and C-myc promote malignancy, relapse, and indicate poor prognosis in patients with relapsed glioma. The elevated levels of β-catenin and c-myc in relapsed glioma were not affected by radiation therapy. The results of this study may provide a new therapeutic target for patients with relapsed glioma.
Knowledge and Perception of the Practice of Nuclear Medicine Among Physicians in Usmanu Danfodiyo University Teaching Hospital, Sokoto
Authors: Isah Ahmed Rufai , Abdulqadir Ibrahim , Adamu Habibullah , Aliyu Usman Malami , Abubakar Sofiyullah , Yunusa Garba Haruna , Jawa Zabah Muhammad
Published: March 2023

Background:

The management of Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, since the year 2011 set the machinery to establish a Department of Nuclear Medicine (NM). The objective of this study is to evaluate the physicians' knowledge and perception of the practice of NM, with a view of improving these when NM services commence at UDUTH, Sokoto.

Methods:

An anonymized electronic questionnaire was used to conduct this cross-sectional study. The questionnaire had three sections, comprising responders' demography, basic knowledge of NM, and physicians' perception of the practice of NM. The data were collated in an Excel spreadsheet (version 16.53, 2019), and the IBM SPSS package (version 27, 2020) was used to conduct the descriptive statistical tests.

Results:

Seventy-six doctors participated in the study. Of this figure, females were 19 (24.7%), whereas 57 (75.3%) were males. In terms of designation, there were 2 (2.6%) house officers, 22 (28.6%) registrars, 25 (32.5%) senior registrars, and 27 (35.1%) consultants. Fifty-one (67.1%) respondents clearly understand what NM is, while 18 (23.7%) wrongly identified NM as the field of medicine that uses machines that produces radiation to diagnose and treat certain illnesses, 2 (2.6%) respondents did not respond, while 5 (6.6%) were not sure. Only three (2.6%) physicians were able to correctly identify the rays/particles that are used in NM (beta rays, gamma rays, alpha rays, and positron), the majority of 25 (32.9%) identified gamma rays as the only rays used in NM.

Conclusion:

The study shows low awareness on what NM is about and the perception on the role of NM in clinical practice is also poor. This has demonstrated the need to enlighten them through lecture and seminar presentations. There is a need for the NM centers in the country to collaborate with the referring clinicians with a view to create awareness on the role of NM services and where these services can be accessed.
Concept of body image and its mental health implications
Authors: Choudhary Prashant , Upadhyay Saumya , Kar Sujita Kumar
Published: March 2023

Individual's impressions about their bodies may differ from cultural standards and expectations and can lead to either contentment or discontent. Dissatisfaction with one's body has been observed in populations as young as 5–7 years old and the elderly. Variations are also noticed across ages, gender, and social strata, also influenced by peer feedback and societal assessment. A broad spectrum of mental health issues as well many physical conditions associated with obvious or acquired disfigurements are impacted by body image. Many instruments, including self-report questionnaires and projective tests, have been developed over time to measure various aspects of body image across different stages of life. Treatment options include cognitive behavioral therapy, embodiment intervention techniques, mirror therapy, and assistance from virtual reality.
Endometrioid Adenocarcinoma within an Endometriotic Cyst in the Mesosalpinx
Authors: Alharbi Nouf Faisal , Hajla Mohammed Mubarak , Elsharkawy Tarek , Alharbi Ashraf , Abdelsayed Randa , Aljama Fathia Ebrahim
Published: March 2023

Endometriosis-related neoplasms may arise within endometriotic cysts of organs of the female genital tract or other organ systems. Herein, we present a case of endometrioid adenocarcinoma arising within an endometriotic cyst in the mesosalpinx. A 27-year-old single female presented to the clinic with a history of right hypochondrial pain. Pelvic MRI revealed a bulky uterus with three intramural uterine fibroids and a complex cyst in the mesosalpinx. The excised cyst showed predominantly confluent growth of relatively well-defined glands resembling proliferative-phase endometrium in a background of endometriosis. The tumor was diagnosed as endometrioid adenocarcinoma within an endometriotic cyst, pathologic stage pT1a. She was referred to the oncology team, where a positron emission tomography scan showed unremarkable results. Although these neoplasms have been reported in various locations within the female genital tract, endometrioid adenocarcinoma arising from endometriosis in the mesosalpinx is seldom reported.
Aortic Stenosis Detection Using Spectral Statistical Features of Heart Sound Signals
Authors: Kumar S. V. Mahesh , Dhinakar P. , Nishanth R.
Published: March 2023

INTRODUCTION: Aortic stenosis (AS) is a severe complicated heart valve disease. This valve abnormality is a slow-progressive condition and mostly asymptomatic. Hence, there is a need for a rapid non-invasive AS diagnosis method with minimal feature extraction. 
OBJECTIVE: In this paper, we proposed a rapid spectral analysis-based statistical feature extraction method to identify the AS stages with the minimum number of features.
METHODS: In this study, the heart sound signals were collected from the medical database and transformed into the frequency domain for further spectral feature analysis. We used the windowing technique to condition the heart signals before spectral analysis. The spectral statistical features were extracted from the computed frequency spectrum. The range of statistical features was compared for normal, early, and delayed AS groups.
RESULTS: In experiments, the normal, early, and delayed AS heart sound signals were used. The experimental results show the statistical difference between the normal and AS heart sound signal spectrums. The normal/unhealthy condition of a heart was identified using the statistical features of the frequency spectrum.
CONCLUSION:  The experimental results confirmed that the statistical features derived from the heart sound signal spectrums were varied according to the AS condition. Hence, the spectral statistical features can be considered as a rapid predictor of AS.
Подход Хорошкина-Толстого для квантовых супералгебр
Authors: Razumov Aleksandr Vital'evich
Published: March 2023

Центральным объектом квантово-алгебраического подхода к изучению квантовых интегрируемых систем служит универсальная $R$-матрица, являющаяся элементом пополненного тензорного произведения двух экземпляров квантовой алгебры. Различные объекты интегрируемости строятся посредством выбора представлений для сомножителей этого тензорного произведения. Имеется два подхода к построению явных выражений для универсальной $R$-матрицы. Один из них основан на использовании автоморфизмов Люстига, а другой основан на понятиях нормального упорядочения и $q$-коммутатора. В случае квантовой супералгебры первый подход использовать нельзя в связи с тем, что явное выражение для автоморфизмов Люстига в общем случае неизвестно. Можно использовать второй подход, хотя он и требует соответствующих модификаций. В настоящей работе осуществлены необходимые модификации метода, метод используется для нахождения $R$-оператора для квантовой интегрируемой системы, связанной с квантовой супералгеброй $\mathrm U_q(\mathcal{L}(\mathfrak{sl}_{M | N}))$.
Oxygen Consumption with High-Flow Nasal Oxygen versus Mechanical Ventilation— An International Multicenter Observational Study in COVID–19 Patients (PROXY–COVID)
Authors: Botta Michela , Caritg Oriol , van Meenen David M.P. , Pacheco Andrés , Tsonas Anissa M. , Mooij Willemijn E. , Burgener Alessia , Manrique Hehl Tosca , Shrestha Gentle S. , Horn Janneke , Tuinman Pieter R. , Paulus Frederique , Roca Oriol , Schultz Marcus J.
Published: March 2023

The COVID–19 pandemic led to local oxygen shortages worldwide. To gain a better understanding of oxygen consumption with different respiratory supportive therapies, we conducted an international multicenter observational study to determine the precise amount of oxygen consumption with high-flow nasal oxygen (HFNO) and with mechanical ventilation. A retrospective observational study was conducted in three intensive care units (ICUs) in the Netherlands and Spain. Patients were classified as HFNO patients or ventilated patients, according to the mode of oxygen supplementation with which a patient started. The primary endpoint was actual oxygen consumption; secondary endpoints were hourly and total oxygen consumption during the first two full calendar days. Of 275 patients, 147 started with HFNO and 128 with mechanical ventilation. Actual oxygen use was 4.9-fold higher in patients who started with HFNO than in patients who started with ventilation (median 14.2 [8.4–18.4] versus 2.9 [1.8–4.1] L/minute; mean difference = 11.3 [95% CI 11.0–11.6] L/minute; P < 0.01). Hourly and total oxygen consumption were 4.8-fold (P < 0.01) and 4.8-fold (P < 0.01) higher. Actual oxygen consumption, hourly oxygen consumption, and total oxygen consumption are substantially higher in patients that start with HFNO compared with patients that start with mechanical ventilation. This information may help hospitals and ICUs predicting oxygen needs during high-demand periods and could guide decisions regarding the source of distribution of medical oxygen.
On the Usability of Available Digital Tools for Reconstructive TextualEditing
Authors: Roelli Philipp
Published: March 2023

This article reviews some of the digital tools currently available for reconstructive textual editing. First the main idea of reconstructive textual editing is summarised, then its steps amenable to algorithmic description are compared to similar ones in evolutionary biology. The the unequal ability of its variants to be relationship revealing is an important difference between the two fields. Two Latin texts with a complicated transmission are then introduced and used as data to illustrate some available tools in praxi. The main focus is on stemma reconstruction. Some steps of the process can already be largely automated, especially collating texts. On the whole it is found that tree-constructing software is of little help in the case of the medical text Liber Aurelii, whereas it is somewhat more helpful for Plato of Tivoli’s translation of the Centiloquium. In a concluding part, the main problems for algorithmic approaches to the stemma are discussed: incomplete witnesses leading to only partly overlapping text samples, contamination in some witnesses, and rooting the automatically generated trees.
Application of Panoramic Dental X-Ray Images Denoising
Authors: ÇETİN TAŞ İclal
Published: March 2023

Dental X-ray imaging helps dentists detect many problems such as caries, cysts and jaw structure problems. Clinical diagnosis and preventive examinations of dental structures play an important role by providing a comprehensive imaging evaluation with panoramic x-rays for dentists. However, researchers primarily use image processing methods to analyze and improve a dental X-ray image and increase its contribution to the diagnostic time. Image segmentation, classification, threshold-based analysis, artificial neural networks, frequency-based methods are the most widely used image processing techniques to analyze medical images and assist in the development of computer aided medical diagnosis systems. In this study, images were analyzed in terms of noise removal by using convolutional neural networks and binary and wavelet filters to improve the images that were distorted and lost their clarity as a result of noise caused by various reasons during shooting. The performances of these methods were compared and it was seen that successful results were obtained in different noise types by using convolutional neural networks.
A Novel Intrusion Detection System Using Multiple Linear Regression
Authors: Koushik Paul  , Sayandeep Paik  , Siddhartha Kuri  , Soumyadip Majumder  , Avijit Kumar Chaudhuri
Published: March 2023

The internet is no doubt the biggest and the most important tool of modern civilisation. But along with its numerous benefits, it also comes with its own set of risks, the most important of them being breaches in security and privacy. An anomaly-based Intrusion Detection System (IDS) is a type of security system that is used to detect and alert on unusual or abnormal behaviour that may indicate an attack or intrusion. Unlike signature-based IDS, which rely on known patterns of attack, anomaly-based IDS is designed to detect previously unseen or unknown attacks by identifying deviations from normal patterns of behaviour. Multiple linear regression is a statistical technique used to analyse the relationship between a dependent variable and multiple independent variables. In this technique, a linear equation is established between the dependent variable and multiple independent variables, with the aim of predicting the value of the dependent attribute for a given set of values of the independent attribute. In this paper, we collected a data set of 125974 entries and 42 attributes from Kaggle, pre-processed the data and used logistic regression to predict the dependent variable (called xAttack) using 25 independent variables, as we found a high correlation between the aforementioned variables The results are simulated using 10-fold cross validation, using various train test splits of the data set. The data has been split into 80-20,50-50, and 66-34. After testing the given data set in different train test splits, an accuracy of 92.73 was achieved.
Relationship Between Urobilinogen and Singing
Authors: Idrees Fatima , Hussain Syed Bilal , Qadir Muhammad Imran , Yousaf Tayyaba
Published: March 2023

Singing may cause urobilinogen in a person by releasing some sort of chemicals from brain. The standard average of students that took part in this experiment was 90 students. They were from Bahauddin Zakariya University Multan. They were mostly of age 18 to 22. The aim of this study was to find whether there is any tie-up between singing and urobilinogen level. The student’s opinions were noted after examining their urobilinogen level. We found out that most of the students have 0.1 mg/dL urobilinogen in their urine which is normal.
Time-Dependent Change of Plant Nutrients in Italian Grass (Lolium multiflorum) after Foliar Fertilization
Authors: ÖNER Nureddin , DEMİRKIRAN Ali Rıza , ÖNER Filiz
Published: March 2023

This research was carried out in the Keyfoturağı area of Menteşe district of Muğla province in 2021 to examine the effects of different fertilizer doses with algae on the grass yield and plant nutrient content of Italian grass (Lolium multiflorum attain). The fertilizer applications as algae (A, DynaMix) and algae + fertilizer 1 (A+F1), algae + fertilizer 2 (A+F2) were applied at different rates to Italian grass plant. Then, the whole plant sample is taken for nine days from the first day and the plants were analyzed for the nutrient contents. The data of the applications, leaf sampling times and application x leaf sampling times were statistically analyzed. According to the results of the research, The effect of moisture, nitrogen (N), potassium (K), calcium (Ca), magnesium (Mg), sodium (Na), sülfür (S), boron (B), zinc (Zn), copper (Cu), iron (Fe) and manganese (Mn) contents in the plant were found to be statistically significant (p
Effects on Machinability of Minimum Quantity Lubrication Strategy during Milling of ST52 Steel
Authors: ŞAP Serhat
Published: March 2023

This study focuses on milling under sustainable cutting conditions of ST52 steel, frequently used in the manufacturing industry. ST52 steel is a good candidate as a workpiece because it is inexpensive and readily available. To achieve sustainable conditions, the cutting zone minimum quantity lubrication technology was used during processing. The experiments used three cutting speeds (120-180-240 m min-1), three feed rates (0.12-0.18-0.24 mm rev-1), and a constant depth of cut (0.5 mm). Taguchi L9 orthogonal array was used to reduce repetitions. The response parameters are surface roughness, flank wear, and cutting temperature. As a result, when compared to the dry environment, the minimum quantity lubrication environment improved surface roughness by approximately 62.37%, flank wear by approximately 9.95%, and cutting temperature by approximately 13.82%. In addition, the most effective control factors on response parameters were determined by statistical analysis.
THE EFFECT OF ELECTROLYTE COMPOSITIONS ON THE STRUCTURE AND PROPERTIES OF PEO COATINGS ON PURE Ti SUBSTRATE
Authors: COACA ELISABETA , ANDREI VICTOR AUREL , DULAMA IOANA DANIELA , BANICA ANDREEA LAURA , RADULESCU CRISTIANA , MIHAILESCU CRISTIAN
Published: March 2023

Plasma electrolytic oxidation method was used to form ceramic coatings on pure Ti substrates, using various aqueous solutions of sodium aluminate (15 g/L and 20 g/L, with or without the addition of NaOH, 2 g/L). The PEO process was carried out at constant time and voltage (300 seconds, 200 V). The ceramic coatings obtained by PEO were investigated by SEM, EDS, XRD, XPS and their corrosion behavior has been evaluated. The aim of the study was to understand the role of NaOH in the development of the PEO process and to evaluate the results obtained by short treatments in potentiostatc regime.
OPTICAL ABSORPTION IN SEMICONDUCTOR NANOWIRE MEDIATED BY ELECTRON-POLAR OPTICAL PHONON AND SPIN-ORBIT INTERACTIONS
Authors: Ghukasyan Tigran K.
Published: March 2023

The intrasubband and intersubband absorption of light by free charge carriers in a semiconductor nanowire upon scattering by polar optical phonons mediated by Rashba and Dresselhaus spin-orbit interactions has been studied. The dependence of the absorption coefficient on the energy of the incident photon is investigated by counting the transitions between different conduction subbands. It is shown that the spin-orbit interaction leads to an increase in the coefficient of intrasubband and intersubband absorption of light, with the peaks of the absorption coefficient being determined by the energies of the absorbed photon and the absorbed or emitted phonon. In this case, the difference between the values of the absorption coefficients with or without spin-orbit interaction has maximum in the range of the local minimum of the absorption coefficient obtained by ignoring the spin-orbit coupling.
Nursing Actions after Hip Total Joint Replacement Surgery
Authors: Petravičienė Zita , Bartašiūnienė Vida
Published: March 2023

The joint replacement surgery is one of the greatest achievements of medicine these days. They are one of the most effective surgical interventions, performed recently, both in medical and economic terms [1].

Every year in Lithuania as well as worldwide, the number of joint replacement surgeries is constantly increasing. This is influenced by the ageing population as well as the increasing number of people with chronic degenerative joint diseases [2].

Despite the fact that hip, knee total joint replacement surgeries have become routine orthopedic surgeries, however, special care and nursing by medical employees are required during the postoperative period.

The purpose of the research. To analyze nursing actions after the hip total joint replacement surgery. A quantitative survey has been performed by the questionnaire method; its participants were nurses, working in health care institutions of Utena City.

The research revealed that the nurses shall assess the patient's general condition, his/her vital indicators, the wound, the drains and solve theproblems that have occurred.
Ethiopian University Students’, Lecturers’ and Administrators’ Perceptions of Interculturally Competent Persons
Authors: Ayana Desta , Sercu Lies
Published: March 2023

Purpose: This study’s aim was to investigate Ethiopian university students’, lecturers’, and administrators’ perceptions of the dispositions (savoir-être) of interculturally competent persons.

Methodology: Building on seminal models of intercultural competence, a survey instrument was created to inquire into the three stakeholder groups’ perceptions. The survey was completed by 638 participants.

Findings: The paper highlights similarities and differences between students, lecturers, and administrators. The findings also show that African and western characteristics associated with interculturally competent persons reflect the respondents’ personal and professional roles.

Unique Contribution to Theory, Practice and Policy: This study is the first to study Ethiopian students’, lecturers’ and administrators’ perceptions of interculturally competent persons. The study’s findings provide a baseline on which curricula and policies can build in order to promote intercultural competence in Ethiopian universities.
CURSOS DE SAÚDE EM MODALIDADE À DISTÂNCIA: UMA PREOCUPAÇÃO CONSTANTE
Authors: Dos Santos Pessôa Jussara Maria
Published: March 2023

Nos últimos anos a procura por cursos em modalidade à distância vem crescendo cada vez mais, e por consequência mais instituições têm aumentado a grade de cursos oferecidos nessa modalidade. Entretanto, alguns cursos, principalmente os da área de saúde, merecem uma atenção especial devido à inevitável necessidade de aulas práticas. O objetivo do presente trabalho é expor, através de um levantamento bibliográfico, a atual situação dos cursos em EaD, com destaque para os cursos da área de saúde, bem como as medidas tomadas pelas instituições para cumprir as exigências dos órgãos regulamentadores e a visão dos alunos sobre a importância das aulas práticas nesses cursos.
THERMAL BEHAVIOR OF DIFFERENT FLUIDS IN ELECTROMAGNETIC INDUCTION
Authors: ÇATAK Mustafa , AYDOĞAN Tuncay , SELVER Ramazan
Published: March 2023

In this study, the thermal behavior of different fluids in electromagnetic induction heating was investigated. Induction coil, heat exchanger and control circuit designs were made for the research. An experimental setup was created by using a temperature gauge, tachometer, DC motor and circulation pump. The thermal behavior of 650 ml of boron oil, pure water, olive oil, sunflower oil, motor oil and boron – pure water composite fluids after their circulation at 700 rpm and 92 minutes from the experimental setup was investigated. The heat exchanger surface temperature, circulation pipe temperature, beaker temperature and ambient temperature were recorded. The heat exchanger surface temperature, circulation pipe temperature, beaker temperature and ambient temperature were recorded. The specific heat capacity values of the same fluids were also calculated. At the end of the research, it was observed that the temperature of 92 minutes under the same electromagnetic induction and ambient conditions showed values between 79 °C and 95 °C. It has been determined that the most efficient fluid is the engine oil, which has a heating value of 37 °C at the 2nd minute, 85 °C at the 42nd minute and 95 °C at the 92nd minute. It was observed that boron oil, olive oil, sunflower oil, boron – pure water composite mixture and pure water followed, respectively. It has been observed that the specific heat capacity values are inversely proportional to the temperature increase of the fluids.
Methods for determining the critical deformations of wood with various moisture content
Authors: Homon Sviatoslav , Litnitsky Serhii , Gomon Petro , Kulakovskyi Leonid , Kutsyna Iryna
Published: March 2023

During construction of bridges, the possibility of flooding periods should be considered. Therefore, it is necessary to understand the degree of possible deformation of wooden structures and calculate the limit of their plasticity and elasticity at different values of moisture content. Thus, the purpose of study is to find the method for determining the relative critical deformations of wood with different moisture content and analyse the dynamics of their change. Problems of a deformable solid material were investigated by the analysis of a model of complete deformation diagram “stress σс – deformation uс ”, methods of mathematical statistics, and systematic analysis of experimental results. This study allowed formulating the method for determining the relative critical deformations of solid wood at different moisture levels by axial compression along the fibres of experimental samples. Based on the experiment results, the formula for determining the relative critical deformations of solid wood with different moisture was proposed. The dynamics of changes in critical relative deformations at different moisture, and its elastic and plastic components were presented. It was found that in case of drying wood from 30 to 12%, the plastic component of relative critical deformations decreases and the elastic one, on the contrary, increases. The findings can be used in the deformation calculation methodology for wooden elements and structures of bridges, hydraulic structures, buildings, taking into account the changes in the moisture content of the material
O jogo da velha como alternativa de melhoria no processo de ensino-aprendizagem da Matemática na Educação de Jovens, Adultos e Idosos
Authors: Santos Maxuel Leandro , Cruz Maria Aparecida
Published: March 2023

RESUMO: Esta pesquisa teve como objetivo analisar se a construção do conhecimento sobre a teoria dos conjuntos com o uso do Jogo da Velha na EJA contribuiu para a melhoria no processo de ensino-aprendizagem, na participação e na interação entre os estudantes do 1º período do Ensino Médio da Educação de Jovens, Adultos e Idosos (EJAI) da rede estadual de ensino do estado de Alagoas. Para atingir esse objetivo foi realizado um estudo bibliográfico que contemplou a caracterização dos os estudantes da EJAI, aspectos epistemológicos da inserção de jogos em sala de aula e as particularidades do Jogo da Velha.  A realização do trabalho caracterizou-se como pesquisa-ação, com abordagem qualiquantitativa. A partir dessa análise e da Metodologia da Pesquisa utilizada com questionário de identificação, lista de exercícios e jogo, foi confeccionado um recurso didático denominado Jogo da Velha com Conjuntos que consiste em uma utilização do tradicional Jogo da Velha com algumas alterações, onde nesse novo formato foram abordados os conteúdos da Teoria dos Conjuntos, e após a análise dos dados obtidos como resultado da pesquisa foi possível concluir que o Jogo da Velha com Conjuntos logrou êxito nos objetivos propostos, evidenciando a melhoria no aprendizado com a inserção de jogos.

Palavras-chave: Jogo da Velha, Matemática, Conjuntos.

 

ABSTRACT: This research aimed to analyze whether the construction of knowledge about the theory of sets with the use of Jogo da Ticla in EJAI contributed to the improvement in the teaching-learning process, in the participation and in the interaction between students of the 1st period of High School Youth, Adult and Elderly Education (EJAI) of the state education network in the state of Alagoas. To achieve this objective, a bibliographical study was carried out that included the characterization of the EJAI students, epistemological aspects of the insertion of games in the classroom and the particularities of the Tic-tac-toe game. The accomplishment of the work was characterized as action-research, with a quali-quantitative approach. Based on this analysis and the Research Methodology used with an identification questionnaire, list of exercises and game, a didactic resource called Tic-Tac-Tac-Toe with Sets was made, which consists of using the traditional T-Tic-tac-Toe Game with some changes, where in this new format The contents of the Theory of Sets were approached, and after analyzing the data obtained as a result of the research, it was possible to conclude that the Tic-Tac-Toe Game with Sets was successful in the proposed objectives, showing the improvement in learning with the insertion of games.

Keywords: Tic-tac-toe, Mathematics, Sets.
A escola do campo
Authors: Farias Susanne Messias de
Published: March 2023

A escola do campo, por vezes, é tão pequena na estrutura, maior na beleza externa e na força do povo nela habitar, que planta, cuidar e cultiva, dá para vê no olhar de cada ser nela habitar que de lutar em lutar, de grão em grão do litoral ao sertão que alimentar o povão.
 
A educação do campo é construída num espaço de lutas oriunda de um dívida histórica social, que nessa prosa deve-se considerar e valorizar o homem do campo, com suas raízes na base camponês, que debaixo do sol e da chuva incessante, se faz feliz por alimentar sua gente, dai já faz nova plantação com esse mesmo chão.
 
A escola do campo é junção de multisseriada, com tanta meninada! E os professorares que vem de legá-las de distância semeando sonhos e cultivo direitos. Na educação do campo vive dias de lutas, para chegar nos dias de glórias, porque sem batalha não há vitória, sendo assim, a escola tem um papel fundamental nas mudanças que precisam ser efetivadas na realidade do campo.
 
Com tanta coisa boa que tem no campo, uma das melhores é a possibilidades de dinamiza as condições sociais existentes, enquanto projeto de mundo, de homem/mulher e de sociedade, viva a resistência de todos aqueles fazem deste cenário um lugar de educação.
Notas sobre pensar o neofascismo brasileiro em uma chave global
Authors: López Burian Camilo
Published: March 2023

Este artigo dialoga com as ideias desenvolvidas no artigo El neofascismo en Brasil, ¿de lo local a lo global?, de Odilon Caldeira Neto. A partir deste trabalho, destacam-se três aspectos interligados: as contribuições para abordar o neofascismo brasileiro como objeto de estudo, seus vínculos transnacionais e as reflexões sobre a prática intelectual em torno da construção de conceitos e categorias. O próprio texto constitui uma grande contribuição para repensar as particularidades - desde a história, as tradições e as experiências - de um fenômeno que, por sua vez, é atual e global.
Os neofascismos no Brasil e na América Latina: um diálogo com Odilon Caldeira Neto
Authors: Jacheta Riberti Larissa
Published: March 2023

O artigo tem como objetivo estabelecer um diálogo com Odilon Caldeira Neto, autor de “Neofascismo no Brasil, do local ao global?”. Nesse sentido, o artigo propõe debater alguns elementos que possam ser incorporados como fundamentais para o entendimento do neofascismo e das extremas direitas no Brasil e na América Latina. Tais fenômenos parecem recuperar características comuns também aos fascismos clássicos, além de elementos singulares que expressam as condições históricas, sociais, culturais, políticas e econômicas, próprias dos contextos nos quais tais experiencias se expressam.
Architecture After Deleuze and Guattari
Authors: Smith Chris L.
Published: March 2023

This study illuminates the complex interplay between Deleuze and Guattari’s philosophy and architecture. Presenting their wide-ranging impact on late 20th- and 21st-century architecture, each chapter focuses on a core Deleuzian/Guattarian philosophical concept and one key work of architecture which evokes, contorts, or extends it.

Challenging the idea that a concept or theory defines and then produces the physical work and not vice versa, Chris L. Smith positions the relationship between Deleuze and Guattari’s philosophy and the field of architecture as one that is mutually substantiating and constitutive. In this framework, modes of architectural production and experimentation become inextricable from the conceptual territories defined by these two key thinkers, producing a rigorous discussion of theoretical, practical, and experimental engagements with their ideas.
Formalnopravni aspekti derogacije ljudskih prava zbog pandemije kovida 19 u uporednoj ustavnosudskoj praksi
Authors: Beretka Katinka
Published: March 2023

The paper presents the similarities and differences in the argumentation of the constitutional courts of the Republic of Serbia, the Republic of Croatia, Bosnia and Herzegovina, and Hungary when deciding on procedural/formal aspects of human rights derogation and other (restrictive) measures adopted due to COVID-19, such as the competence of bodies ordering restrictive measures, character/quality of their acts, control by the legislature and/or the executive. The commonality is that, despite the courts not neglecting the need for restrictive measures and the general interest in preserving public health, they treated the importance of formal requirements of the rule of law differently in pandemic conditions. The aim of this paper is to identify relevant common criteria and tests for assessing the constitutionality of these measures, in order to increase legal certainty in similar situations in the future, caused by new epidemics.
Aluminum phosphide poisoning
Authors: KARAKUŞ Ali
Published: March 2023

Letter to Editor

Aluminum phosphide poisoning

Dear Editor,

Aluminum phosphide, is a fumigant with high insecticide power in all life stages of insects, which is harmful in stored products.

It is in the form of tablets or granules and is highlylethal and has no antidote.

It inhibits the enyzme of cytochrome oxidase. Complications may develop as a result of inhaling phosphine gas or oral intake. Respiratory, circulatory, gastrointestinal tract andnervous system, kidney and liver may be affected. Shock, ARDS, aspration pnomony, anemia, metabolic acidosis, electrolytic disorder, coma, hipoxy, hemorrhage, pericardide are poorprognosis criterion. Leukopenia indicates severe toxicity. The lethal dose is 0.15-0.5 g and death is inevitableeven when buying 3-5 tablets

Arrhythmia is responsible for death in the first 24 hours.The mortality rate varies between 37-100%.Treatment consists entirely of supportive treatment. (liquid, dopamine, oxygen, mechanical ventilation, gastric washing, activated charcoal,bicarbonate, hemodialysis)We aimed to present the case that developedsystemic complications in follow-up but wedischarged with healing as a result of appropriatefollow-up and treatment.

CASE

A 16-year old female patient was rushed to theemergency room two hours ago for drinking morethan she

knew the amount of the drug containing aluminum phosphide for suicidal purposes.

When the patient arrived, his general condition wasmoderate, conscious, pale sweaty appearance and Tachypnea, BREATHING:26/min, TA:60/40mmhg,Pulse:135/min,,fever:37 degree systemic examination showed no abnormalities.

Initial blood values, ECG and chest x-ray were normal.

The patient was followed up in the emergency department. 1000ml serum physiological started

In order to reduce the formation of phosphine gas(with alkalısm), oral bicarbonate was started.

Ta:100/70mmHg in the 2nd hour of follow-up andchest pain developed.

The first TROPONIN I value was:0.02(0-0.06 ng/ml). In echocardiography, ejection fraction wasdetermined 57%. In the blood gas, PH was 7.32 and there was metabolic acidosis. Her acidosis level improved in the 6th hour of the follow up. The control TROPONİN value was 0.21. Asetilsalisilik acid started at 100 mg. At the 12th hour white blood cell (4-11 k/ml) decreased from 12000 to 4000.However no abnormality was detected in other hemogram values.

At the 20th hour ,her chest pain gone and her troponin values increased up to 1.45.No ECG change detected.Her acidose improved and lokopenia not seen.The patient’s control , liver and kidney function tests and ECHO were normal.No abnormality was detected in the follow ups , polyclinic controls and laboratory values on the third day of the hospitalization. The patient was discharged from the hospital with suggestions.

Aluminum phosphide is an extremely mortal toxic substance.During the follow ups unwanted complications can develop. Merely satisfactory results can be achieved with valid , timely and appropriate supportive treatments
Patterns of Health Services Utilization During Pregnancy, Delivery, and Postpartum Period: Evidence from Pakistan Maternal Mortality Survey
Authors: Zafar Rabia , Sheraz Ayesha , Midhet Farid , Ishfaq Sidra
Published: March 2023

Utilization of health services is a multidimensional behavioural phenomenon, particularly when it comes to pregnancy and delivery concerns. The importance of maternal health care services in reducing maternal mortality and morbidity has received a significant recognition. Most of the maternal deaths can be prevented if women have access to basic antenatal, delivery and postnatal care. However, uptake of maternal health care services is very low even in the areas where they are extensively available. The aim of this study is to assess the pattern and identify underlying factors on maternal health care utilization in Pakistan. Data is taken from Pakistan Maternal Mortality Survey (PMMS) 2019. Logistic regression was performed and adjusted odd ratios were calculated by using three dependent variables – Ideal Antenatal Care (IANC), birth assisted by Skilled Birth Attendant (SBA), and Postnatal Care (PNC). Impact of biological and socio-demographic variables were computed, and findings revealed that with the increase in age, education and household wealth, women are more likely to have better opportunities to use ANC, SBA and PNC. The focus of policy considerations should be on the provision of high-quality services as well as on educating women about the value of receiving such services during pregnancy and the postpartum period through education and awareness campaigns. Moreover, skilled staff and voluntary health workers can be recruited to make future agendas in reducing maternal mortality and morbidity more successful.