bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice
Authors: Tripathi Ashish Kumar , Dabeer Sadaf , Song Jun , Vikulina Tatyana , Roser-Page Susanne , Alvarez Jessica A. , Archer David. R. , Weitzmann M. Neale
Published: December 2024

Sickle cell disease (SCD) is a severe hematological disorder characterized by erythrocyte sickling that causes significant morbidity and mortality. Skeletal complications of SCD include a high incidence of bone loss, especially in vertebrae, leading to fragility fractures that contribute to disease burden. Whether hydroxyurea (HU), a front-line therapy for SCD ameliorates bone disease has not been established. To investigate HU action on SCD-related vertebral defects, we used HU-treated “Townes” mice, an SCD animal model and performed high-resolution micro-computed tomography (µCT) imaging to resolve bone volume and micro-architectural structure of cortical and trabecular bone, the two major compartments contributing to bone mass and strength. Our data revealed that cortical bone was significantly diminished in the vertebrae of skeletally mature (representing adults) and immature (representing children) SCD mice, while only mature mice lost trabecular bone mass. Administration of HU ameliorated cortical bone loss in mature SCD mice, but paradoxically promoted trabecular bone decline in both groups. We further investigated the mechanisms of HU action in wild-type C57BL6/J mice. HU caused dose-dependent trabecular bone loss due to diminished osteoclast and osteoblast function, indicative of a low bone turnover state. Mechanistic investigations in vitro revealed that HU impeded osteoblast-progenitor proliferation and early differentiation, and diminished osteoclastogenic cytokine production, blunting osteoclast formation as well as the activity of mature osteoclasts. HU further, suppressed mitochondrial, but not glycolytic energy metabolism in both differentiating osteoblasts and differentiated osteoclasts. Collectively, these findings reveal that despite ameliorating cortical bone loss, HU inhibits trabecular bone formation and resorption, by suppressing mitochondrial energy metabolism and blunting the differentiation and/or activity of osteoblasts and osteoclasts. Together HU drives a low bone turnover state culminating in trabecular bone loss. Further investigation into HU’s impact on bone in SCD patients is warranted for understanding and managing skeletal complications in this population.
Exosomal miR-320d promotes angiogenesis and colorectal cancer metastasis via targeting GNAI1 to affect the JAK2/STAT3 signaling pathway
Authors: Wu Yawen , Zhang Jie , Li Guanghao , Wang Li , Zhao Yajing , Zheng Baibing , Lin Fanfeng , Xie Li
Published: December 2024

Colorectal cancer is a common malignant tumor, whose growth and metastasis are influenced by numerous factors. MicroRNAs have garnered increasing attention in recent years due to their involvement in tumor development. Exosomes are involved in intercellular signaling and influence tumor development by promoting tumor cell proliferation and metastasis through activation of angiogenesis and other mechanisms. This study aimed to investigate how the exosomes containing miR-320d from colorectal cancer (CRC) cells promote colorectal cancer metastasis by regulating angiogenesis. CRC-derived exosomes containing miR-320d can be transferred to vascular endothelial cells, facilitating their proliferation, invasion, migration, and angiogenesis. By targeting GNAI1, miR-320d in these exosomes reduces GNAI1 levels in endothelial cells, causing more JAK2/STAT3 activation and VEGFA production. This ultimately enhances the migration and angiogenic capacity of vascular endothelial cells. Moreover, CRC patients with high levels of miR-320d in their blood respond better to treatment with bevacizumab. In vivo experiments further proved the role of miR-320d from CRC exosomes in increasing tumor size, blood vessel formation, and the spread of cancer to the liver. In this study, we have demonstrated that exosomal miR-320d promotes cancer cell metastasis and enhances angiogenesis by downregulating GNAI1 expression and enhancing JAK2/STAT3.
Dual functions of silibinin in attenuating aortic dissection via regulating iron homeostasis and endoplasmic reticulum stress against ferroptosis
Authors: Qi Zhen , Wang Qiu-Guo , Huang Meng-Xi , Zeng Yi-Fan , Li Jing-Yu , Duan Zhi-Cheng , Tan Ling , Tang Hao
Published: December 2024

Aortic dissection (AD) poses a significant threat to cardiovascular health globally, yet its underlying mechanisms remain elusive. Smooth muscle cells death and phenotypic switching are critically important pathological processes in AD. Currently, no pharmacological therapies have proven effective in managing AD. This study aims to elucidate the involvement of ferroptosis in AD progression and explore ferroptosis inhibition as a potential therapeutic approach for AD management. Elevated expression of ferroptosis markers (HMOX1, ACSL4, and 4-HNE) was observed in AD patients and β-Aminopropionitrile (BAPN)-induced mice. In vivo administration of silibinin (SIL) attenuated aortic dilation, inflammation, mitochondrial injury, and ferroptosis. SIL treatment enhanced cell viability and mitochondrial function while reducing reactive oxygen species (ROS) generation and mitigating ferroptosis in primary human aortic smooth muscle cells (HASMCs) induced by RSL3 or IKE. Mechanistically, RNA-sequencing analysis identified dysregulation of iron homeostasis and endoplasmic reticulum stress, which were modulated by SIL. Molecular docking, cellular thermal shift assay, drug affinity responsive target stability, and surface plasmon resonance analysis confirmed HMOX1 as a direct target of SIL, highlighting its role in modulating iron homeostasis. Moreover, NCT-502, a PHGDH inhibitor, reversed the protective effect of SIL in RSL3-induced HASMCs. Conversely, 4-PBA and ZnPP demonstrate a facilitative role. This suggests that SIL plays a crucial role in ferroptosis development by modulating iron homeostasis and endoplasmic reticulum stress-mediated serine biosynthesis, both in vitro and in vivo. Iron homeostasis and endoplasmic reticulum stress of HASMCs drive the development of aortic dissection. These findings unveil a novel role of SIL in mitigating ferroptosis in HASMCs, offering a promising therapeutic avenue for treating AD.
A dataset of geotechnical parameters based on international literature to characterise lithotypes in Italy
Authors: Monte Nunzia , Bucci Francesco , Mevoli Federica Angela , Santangelo Michele , Reichenbach Paola , Di Matteo Lucio , Marchesini Ivan
Published: December 2024

Geological and lithological maps provide essential spatial data for various environmental assessments and studies. However, these maps lack detailed quantitative information on the geotechnical characteristics of rocks and soils, which limits their use for modelling purposes. This study addresses this gap by compiling a comprehensive database of over 2300 geotechnical parameter records searching the international literature. Focusing on cohesion, friction angle, and porosity, we analyse their distributions across different lithotypes, emphasising their significance in slope stability modelling. For the Italian territory, the collected information was used to associate geotechnical parameters to the lithological classes as identified by Bucci et al. 2022. These types of reclassified maps may provide researchers and stakeholders with a comprehensive dataset useful for slope stability assessment and land management at small scale. Descriptive statistics and validation from grey literature underscore the dataset’s utility in enhancing geotechnical characterizations and supporting geological hazard assessments.
Global Gridded Crop Production Dataset at 10 km Resolution from 2010 to 2020
Authors: Qin Xingli , Wu Bingfang , Zeng Hongwei , Zhang Miao , Tian Fuyou
Published: December 2024

The global gridded crop production dataset at 10 km resolution from 2010 to 2020 (GGCP10) for maize, wheat, rice, and soybean was developed to address limitations of existing datasets characterized by coarse resolution and discontinuous time spans. GGCP10 was generated using a series of adaptively trained data-driven crop production spatial estimation models integrating multiple data sources, including statistical data, gridded production data, agroclimatic indicator data, agronomic indicator data, global land surface satellite products, and ground data. These models were trained based on agroecological zones to accurately estimate crop production in different agricultural regions. The estimates were then calibrated with regional statistics for consistency. Cross-validation results demonstrated the models’ performance. GGCP10’s accuracy and reliability were evaluated using gridded, survey, and statistical data. This dataset reveals spatiotemporal distribution patterns of global crop production and contributes to understanding mechanisms driving changes in crop production. GGCP10 provides crucial data support for research on global food security and sustainable agricultural development.
Craving induction through virtual reality cue-exposure for patients with alcohol dependence in rehabilitation treatment
Authors: Tsamitros N. , Gutwinski S. , Beck A. , Lange Mussons S. , Sebold M. , Schöneck R. , Wolbers T. , Bermpohl F. , Heinz A. , Lütt A.
Published: December 2024

New therapeutic approaches for alcohol dependence (AD) include virtual reality (VR)-based treatments offering scalable options for cue exposure (CE), a well-established strategy in cognitive behavioral therapy. This study aimed to evaluate the feasibility and tolerability of a new VR-CE paradigm. On an explorative basis, factors influencing the induction of craving were examined. This single-arm monocentric clinical study included n = 21 patients with AD in inpatient rehabilitation treatment, that completed one VR-CE session including confrontation with alcohol-associated stimuli. Measurements of subjective craving before, during and after exposure, affective states, VR side effects as cybersickness and the sense of presence in VR were conducted. Craving levels during and directly after VR-CE were significantly higher than before the intervention. Craving levels 20 min after VR-CE did not significantly differ compared to those before VR-CE. Patients described a pronounced sense of presence and only mild symptoms of cybersickness. Craving was significantly correlated with cybersickness. While positive affect decreased throughout the VR exposure, negative affect did not differ significantly in pre-post-comparisons. This study shows that craving induction through our VR-CE paradigm is feasible and well-tolerated by patients with AD in long-term rehabilitation. These results contribute to the development and future research of therapeutic VR-CE approaches.
Decoding skin cancer classification: perspectives, insights, and advances through researchers’ lens
Authors: Ray Amartya , Sarkar Sujan , Schwenker Friedhelm , Sarkar Ram
Published: December 2024

Skin cancer is a significant global health concern, with timely and accurate diagnosis playing a critical role in improving patient outcomes. In recent years, computer-aided diagnosis systems have emerged as powerful tools for automated skin cancer classification, revolutionizing the field of dermatology. This survey analyzes 107 research papers published over the last 18 years, providing a thorough evaluation of advancements in classification techniques, with a focus on the growing integration of computer vision and artificial intelligence (AI) in enhancing diagnostic accuracy and reliability. The paper begins by presenting an overview of the fundamental concepts of skin cancer, addressing underlying challenges in accurate classification, and highlighting the limitations of traditional diagnostic methods. Extensive examination is devoted to a range of datasets, including the HAM10000 and the ISIC archive, among others, commonly employed by researchers. The exploration then delves into machine learning techniques coupled with handcrafted features, emphasizing their inherent limitations. Subsequent sections provide a comprehensive investigation into deep learning-based approaches, encompassing convolutional neural networks, transfer learning, attention mechanisms, ensemble techniques, generative adversarial networks, vision transformers, and segmentation-guided classification strategies, detailing various architectures, tailored for skin lesion analysis. The survey also sheds light on the various hybrid and multimodal techniques employed for classification. By critically analyzing each approach and highlighting its limitations, this survey provides researchers with valuable insights into the latest advancements, trends, and gaps in skin cancer classification. Moreover, it offers clinicians practical knowledge on the integration of AI tools to enhance diagnostic decision-making processes. This comprehensive analysis aims to bridge the gap between research and clinical practice, serving as a guide for the AI community to further advance the state-of-the-art in skin cancer classification systems.
Using population register data and capture-recapture models to estimate over-coverage in Sweden
Authors: Santos Bruno , Mussino Eleonora , Drefahl Sven , Matechou Eleni
Published: December 2024

Over-coverage occurs when individuals who reside in a country leave or pass away, and this demographic event is not recorded in population registers, leading to population size overestimation. This problem can have important policy and decision-making consequences. With the increased reliance on incomplete but overlapping official registers for documenting whole populations or subgroups of populations, there is a need for more sophisticated modelling techniques that reliably estimate population size, and hence over-coverage, from such registers. Previous approaches have considered multiple systems estimation (MSE) for monitoring over-coverage, but MSE does not naturally extend to cases where individuals are followed over time. In this paper, motivated by the case study of Sweden, we develop a capture-recapture (CR) modelling framework for population registers that allows us to estimate the population size each year, the probability of presence for each individual in the population, conditional on their records, each year and to quantify the effect of demographic characteristics on the probability of emigration and re-immigration, amongst other parameters. Our results suggest that the CR approach, which accounts for the whole time series for each individual, gives a more realistic estimate of the population size compared to existing, deterministic approaches, especially when considering the subgroup of newly arrived individuals, and that it provides new insights on individual behaviour in terms of migration patterns than existing MSE approaches.
Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice
Authors: Cao Yunqing , Popp Oliver , Milani Niccolo , Qadri Fatimunnisa , Kühn Ralf , Mertins Philipp , Bader Michael , Alenina Natalia
Published: December 2024

Serotonin exerts numerous neurological and physiological actions in the brain and in the periphery. It is generated by two different tryptophan hydroxylase enzymes, TPH1 and TPH2, in the periphery and in the brain, respectively, which are members of the aromatic amino acid hydroxylase (AAAH) family together with phenylalanine hydroxylase (PAH), degrading phenylalanine, and tyrosine hydroxylase (TH), generating dopamine. In this study, we show that the co-chaperone DNAJC12 is downregulated in serotonergic neurons in the brain of mice lacking TPH2 and thereby central serotonin. DNAJC12 has been described to regulate the stability of PAH and mutations in its gene cause hyperphenylalaninemia and neurological symptoms in patients. We show that DNAJC12 also binds and stabilizes TPH1 and TPH2 in transfected cells. In order to clarify the importance of DNAJC12 in the regulation of neurotransmitter synthesis and phenylalanine degradation in vivo, we generated DNAJC12-deficient mice. These mice show reduced levels and activity of PAH, TPH2, and TPH1 in liver, brain, and pineal gland, respectively, and experience hyperphenylalaninemia and central and peripheral serotonin deficiency. These data support a pivotal role of DNAJC12 in the regulation of AAAH and thereby in neurotransmitter synthesis and phenylalanine homeostasis.
A topological route to engineering robust and bright supersymmetric laser arrays
Authors: Datta Soujanya , Alizadeh Mohammadmahdi , El-Ganainy Ramy , Roychowdhury Krishanu
Published: December 2024

In recent years, several proposals that leverage principles from condensed matter and high-energy physics for engineering laser arrays have been put forward. The most important among these concepts are topology, which enables the construction of robust zero-mode laser devices, and supersymmetry (SUSY), which holds the potential for achieving phase locking in laser arrays. In this work, we show that the relation between supersymmetric coupled bosonic and fermionic oscillators on one side, and bipartite networks (and hence chiral symmetry) on another side can be exploited together with non-Hermitian engineering for building one- and two-dimensional laser arrays with in-phase synchronization. To demonstrate our strategy, we present a concrete design starting from the celebrated Su-Schrieffer-Heeger (SSH) model to arrive at a SUSY laser structure that enjoys two key advantages over those reported in previous works. Firstly, the design presented here features a near-uniform geometry for both the laser array and supersymmetric reservoir (i.e., the widths and distances between the cavity arrays are almost the same). Secondly, the uniform field distribution in the presented structure leads to a far-field intensity that scales as N2 where N is the number of lasing elements. Taken together, these two features can enable the implementation of higher-power laser arrays that are easy to fabricate, and hence provide a roadmap for pushing the frontier of SUSY laser arrays beyond the proof-of-concept phase.
A high-temperature multiferroic Tb2(MoO4)3
Authors: Tajima Shimon , Masuda Hidetoshi , Nii Yoichi , Kimura Shojiro , Onose Yoshinori
Published: December 2024

Magnetoelectric mutual control in multiferroics, which is the electric control of magnetization, or reciprocally the magnetic control of polarization has attracted much attention because of its possible applications to spintronic devices, multi-bit memories, and so on. While the required working temperature for the practical application is much higher than room temperature, which ensures stable functionality at room temperature, the reported working temperatures were at most around room temperature. Here, we demonstrated magnetic control of ferroelectric polarization at 432 K in ferroelectric and ferroelastic Tb2(MoO4)3, in which the polarity of ferroelectric polarization is coupled to the orthorhombic strain below the transition temperature 432 K. The paramagnetic but strongly magnetoelastic Tb3+ magnetic moments enable the magnetic control of ferroelectric and ferroelastic domains; the ferroelectric polarization is controlled depending on whether the magnetic field is applied along [110] or [1$$\bar{1}$$

1

¯

0]. This result may pave a new avenue for designing high-temperature multiferroics.
Introduction to Nanomedicine and Nanopharmaceuticals
Authors: Beus M. , Božičević L. , Mamić I. , Turčić P. , Ventosa N. , González-Mira E. , Köber M.
Published: December 2024

Nanotechnologies applied to medicine offer engineered, tuneable and intriguing materials for solving unmet problems in healthcare. However, the challenges of bridging the translational gap between lab and practice in the industrial context for nano-enabled pharmaceuticals still remain and include limited guidance on regulatory-relevant information and approaches. Despite their great potential, less than 200 nanopharmaceuticals are currently present on the market and in clinical use. This chapter introduces the reader to the world of nanomedicine and nanopharmaceuticals, as well as a description of all the different types of nanopharmaceuticals that are presented in the subsequent chapters.
Graphene-based Multifunctional Nanomaterials for Biomedical Applications
Authors: Almeida Ana Catarina , Santos Carla I. M. , Catalano Enrico , Neves M. Graça P. M. S. , Gonçalves Gil
Published: December 2024

Graphene-based nanomaterials (GBNM) have gained significant attention in the field of biomedical applications, particularly in oncology. These nanomaterials possess unique characteristics such as a large surface area, chemical versatility, and intrinsic optical properties, which make them highly suitable for various cancer-related applications. One key advantage of graphene-based nanomaterials is their ability to develop multifunctional nanoplatforms, offering new opportunities in different medical fields like bioimaging, diagnosis, drug-delivery, therapy and biosensing. This chapter aims to provide a systematic discussion on the synthesis, structure and properties of relevant GBNM, with particular emphasis on graphene quantum dots (GQDs). Additionally, GQDs will be explored as a nanoplatform for the chemical conjugation of tetrapyrrolic macrocycles like porphyrins, corroles and phthalocyanines. With this synergistic approach, it was possible to combine the benefits of both components leading to new agents with improved features for cancer diagnosis, therapy and biosensing.
Introduction of the year 2023
Authors: Quindt M. A. , Jo T. , Nicchio L. , Benazzi V. , Protti S. , Crespi S.
Published: December 2024

In the introduction chapter we introduce the volume and its three sections, namely critical reviews, highlights on recent “hot” topics and SPR lectures in photochemistry. Furthermore, the chapter includes the most significant editorial releases in photochemistry in 2023, by presenting awards, handbooks, special issues and reviews.
Recent advances in photoorganocatalysis (2019–2023)
Authors: Gkizis Petros L. , Kokotos Christoforos G.
Published: December 2024

From 2008 until now, the advent of photochemistry has offered a plethora of synthetic opportunities to chemists worldwide. The ability of light to generate reactive species under mild reaction conditions provided access to unexplored reaction pathways. Lately, the development of photochemical reactions employing small organic molecules as catalysts has increased. Serving the basic principles of Green Chemistry, small organic molecules have proven to be an excellent alternative to the use of metal-based complexes, performing elegant organic transformations. Their use is based on their ability to mediate photochemical events, such as Single Electron Transfer (SET), Energy Transfer (EnT) and Hydrogen Atom Transfer (HAT). Furthermore, there have been reports on the capability to form Electron Donor–Acceptor (EDA) complexes facilitating challenging organic transformations. Herein, we will focus on the photochemical reactions promoted by small organic molecules during the last 5 years (2019–2023).
Perfluoroalkylation of aliphatic substrates via photoinduced radical processes
Authors: Bonesi Sergio M. , Postigo Al
Published: December 2024

Over the past few years, photochemical perfluoroalkylation reactions of aliphatic substrates have emerged as a topic of research within synthetic organic chemistry because organic molecules properly substituted with fluoroalkyl motifs have generated significant interest among synthetic/medicinal and materials science chemists. Examination of a variety of photoinduced perfluoroalkylation reactions involving aliphatic substrates will be discussed, showcasing both methodological versatility and synthetic utility. Examples illustrating their applications and mechanistic intricacies will be explored. Numerous photochemical synthetic strategies for fluoroalkylation reactions have been documented, with radical protocols standing out as prominent in the realm of perfluoroalkylation methods. Specifically, the addition reactions of perfluoroalkyl radicals RF (RF = CnF2n+1, n > 1) to unsaturated organic substrates represent a direct and efficient means to access fluoroalkylated frameworks. Therefore, some selected studies will encompass the synthesis of perfluoroalkyl-substituted vinyl, alkynyl, and allylic compounds, as well as hydro-, iodo-, and oxy-perfluoroalkylated alkanes and olefins. Additionally, the syntheses of perfluoroalkyl-substituted carbonyl compounds, enamides, amides, thioamides, and hydrazones, along with multicomponent perfluoroalkylation reactions, will be explored.
Localized surface plasmon resonance sensing based on monometallic gold nanoparticles: from material preparation to detection of bioanalytes
Authors: Zhang Peng , Hou Huizhen , Xu Songshi , Wen Yingfei , Zhang Yonghui , Xing Fei
Published: December 2024

This article provides an overview of various preparation methods for gold nanoparticles and their diverse strategies based on localized surface plasmon resonance sensing in the field of biomedical detection.
Non-suppressed ion chromatography-tandem electrospray mass spectrometry using a short column for simultaneous analysis of dichloroacetic acid, trichloroacetic acid, and bromate: aqueous ammonia as the eluent additive
Authors: Peng Mingguo , Chen Jiali , Cheng Shi , Zhang Huaicheng , Pu Liangtao , Du Erdeng , Cheng Qingfeng , Zuo Yanting , Li Aimin
Published: December 2024

A novel, simple, and quick non-suppressed IC-MS method was established for simultaneous detection of dichloroacetic acid, trichloroacetic acid, and bromate based on a short guard column and ammonia alkaline additive.
An integrated magnetoimpedance biosensor microfluidic magnetic platform for the evaluation of the cardiac marker cTnI
Authors: Yang Zhen , Chen Jingyuan , Liu Mengyu , Huang Jiabao , Liang Jieping , Zhu Mengjiao , Shen Yuanwei , Li Danqing , Lei Chong , Sun Xuecheng
Published: December 2024

The integrated magnetoimpedance biosensor microfluidic magnetic platform.
In situ constructed polymer-layer-modified solid electrolyte enables high-performance all-solid-state batteries
Authors: Liu Jikang , Cai Lucheng , Peng Jun , Teng He , Li Linyan , Feng Daoyan , Li Huihao , Lee Jonghee , Ying Hangjun , Han Wei-Qiang
Published: December 2024

PEGDA and [VBIM][TFSI] are crosslinked and integrated in Li6PS5Cl to obtain polymer-containing composite solid-state electrolyte (LiPSCl@PCSSE) by in situ polymerization, and excellent performance demonstrates its practical application.
Concave Fe2O3 nanocubes with high-index facets for ammonia production from electrocatalytic nitrate reduction
Authors: Zhang Yuwei , Xu Mingyang , Zhou Jiaxin , Yao Fen , Liang Hanfeng
Published: December 2024

An iron oxide catalyst with high-index (1238) and (1344) facets achieves a high faradaic efficiency of 96.54% and a production rate of 1.13 mmol h−1 cm−2 towards electrocatalytic nitrate reduction to ammonia at 250 mA cm−2.
Photoinduced synthesis of trisubstituted allylic molecules via migratory allylation of olefins
Authors: Xia Dingding , Zhang Na , Zhong Mingdong , Wang Weijie , Li Qiannan , Zhang Yu , Zhang Wei-Dong
Published: December 2024

Herein, we report a transition-metal-free method to afford diverse trisubstituted allylic molecules via migratory allylation of olefins under light irradiation. The broad substrate scope of this reaction demonstrates its applicability and efficiency.
Green solvent strategies for the sustainable development of perovskite solar cells
Authors: Lee David Sunghwan , Lee Hyong Joon , Song Yunmi , Park Jin Kyoung , Heo Jin Hyuck , Im Sang Hyuk
Published: December 2024

This feature article provides a thorough summary on replacing toxic solvents with non-toxic green solvents for sustainable perovskite solar cells.
Recent advances in the development of enantiopure BODIPYs and some related enantiomeric compounds
Authors: Sultan Shaista , Crovetto Luis , Rios Ramon
Published: December 2024

During the process of developing smart chiroptical luminophores, BODIPYs have emerged as candidates of utmost importance. Here in we will discuss their synthesis.
Correction: Elucidating the influence of side chains on the self-assembly of semi-flexible mesogens
Authors: Gearba Raluca I. , Anokhin Denis V. , Ivanov Dimitri A.
Published: December 2024

Correction for ‘Elucidating the influence of side chains on the self-assembly of semi-flexible mesogens’ by Raluca I. Gearba et al., Chem. Commun., 2025, https://doi.org/10.1039/d4cc05421k.
Properties of the ADN/ANTA cocrystal based on theoretical simulation
Authors: Yu Zhihong , Zhou Liang , Peng Wenlian , Zhuang Zhihua , Xu Hanqing , He Jinyan , Chen Hao , Zhang Pengcheng , Zhang Xinggao
Published: December 2024

In this study, we used molecular dynamics simulation and Monte Carlo methods to study the theoretical properties of the ADN/ANTA cocrystal. In addition, the detonation properties of pure ADN, ANTA and ADN/ANTA cocrystals were calculated.
Study of the pH effects on water–oil–illite interfaces by molecular dynamics
Authors: Arboleda-Lamus Anderson , Muñoz-Rugeles Leonardo , del Campo Jorge M. , Santos-Santos Nicolas , Mejía-Ospino Enrique
Published: December 2024

Surface wettability of illite edge toward water in crude oil models. Non-polar: heptane, Polar B: hexylamine and heptane, Polar A: heptanoic acid and heptane.
Two-fold proton coupled electron transfer of a Ta(v) aniline complex mediated by a redox active NNN pincer ligand
Authors: Pavlidis Sotirios , Alasadi Jasmin , Opis-Basilio Amanda , Abbenseth Josh
Published: December 2024

A Ta(v) complex featuring a redox-active NNN pincer ligand undergoes two-fold PCET to convert coordinated aniline to a phenylimido ligand.
Towards the development of a safer by design mineral photocatalytic paint: influence of the TiO2 modifications on particle release
Authors: Rosset A. , Michaud-Soret I. , Capron I. , Voisin H. , Brochard G. , Bergé V. , Benayad A. , Guiot A. , Clavaguera S. , Artous S.
Published: December 2024

Safer by Design approaches for TiO2-based mineral photocatalytic paints.
Insights in photocatalytic/Fenton-based degradation of microplastics using iron-modified titanium dioxide aerogel powders
Authors: Thirunavukkarasu Guru Karthikeyan , Motlochová Monika , Bavol Dmytro , Vykydalová Anna , Kupčík Jaroslav , Navrátil Michal , Kirakci Kaplan , Pližingrová Eva , Dvoranová Dana , Šubrt Jan
Published: December 2024

Degradation of microplastics (MPs) through the photocatalytic and photo-Fenton process using Fe-modified TiO2 aerogel powders.
Energy and cost-saving potential of combined carbon capture and conversion: a pioneering design of a process intensification concept harnessing CeO2 as a dual-functional material
Authors: Yagihara Koki , Ni Jialing , Wang Anqing , Ohno Hajime , Fukushima Yasuhiro
Published: December 2024

A new process intensification concept, termed combined carbon capture conversion (quad-C), can reduce energy consumption and enhance economic viability for CO2 capture simultaneously, using a dual-functional material.
A universal framework for design and manufacture of deterministic lateral displacement chips
Authors: Mehboudi Aryan , Singhal Shrawan , Sreenivasan S.V.
Published: December 2024

This work aims to alleviate the difficulties associated with the design and manufacture of deterministic lateral displacement (DLD) chips.
Influence of ball milling parameters on the mechano-chemical conversion of polyolefins
Authors: Hergesell Adrian H. , Seitzinger Claire L. , Burg Justin , Baarslag Renate J. , Vollmer Ina
Published: December 2024

Mechano-chemical plastic recycling suffers from low overall yields. We identified the role of key parameters to maximize mechanical impact to increase the productivity of small hydrocarbons, such as propene, from polypropylene.
Bird's eye inspired hyperuniform disordered TiO2 meta-atom based high-efficiency metalens
Authors: Islam Ohidul , Sarker Dip , Mahmood K. B. M. Sharif , Debnath Joyprokash , Zubair Ahmed
Published: December 2024

We proposed bird's eye inspired highly efficient hyperuniform disordered metalens.
An economical synthesis of benzodiazepines using ACT@IRMOF core–shell as a potential eco-friendly catalyst through the activated carbon of thymus plant (ACT)
Authors: Fereydooni Maryam , Ghorbani-Vaghei Ramin , Alavinia Sedigheh
Published: December 2024

Here, a straightforward design is employed to synthesize a nanocatalyst based on a carbon-activated modified metal–organic framework using the solvothermal method.
A color-coordinated approach to the flow synthesis of silver nanoparticles with custom morphologies
Authors: Frank Carly J. , Bourgonje Connor R. , Yaghmaei Mahzad , Scaiano Juan C.
Published: December 2024

We devise simple and readily scaleable photochemical methods to synthesize silver nanostructures of varying size, morphologies, and optical properties using batch and flow strategies.
Computational assessment of the binding modes of the first VHL-recruiting PROTACs designed for oncogenic KRasG12C
Authors: Franca Tanos C. C. , Delaire Eleonore K. M. , Drummond Michael , Ebert Maximilian C. C. J. C. , Ajamian Al , LaPlante Steven R.
Published: December 2024

The representative ternary complexes revealed a predominant binding mode for all compounds, with the two proteins approaching each other in the same orientation.
Thermally stable direct arylation derived terthiophene-isoindigo copolymer for organic solar cell application
Authors: Bekri Nika , Mammo Wendimagegn , Tegegne Newayemedhin A.
Published: December 2024

The stability of polymers is highly dependent on their molecular structure. Sulfoxide formation through thiophene ring opening is a mechanism that compromises the stability of thiophene-based polymers.
A core–shell structural catalyst with graphitic carbon encapsulating Fe3C and Fe3N used for H2O2 activation to degrade norfloxacin
Authors: Tang Wenjing , Kang Xiaowen , Zhang Xuefeng , Chen Li , Huang Haolan , Yang Yingchun
Published: December 2024

A core–shell structural catalyst with graphitic carbon encapsulating Fe3C and Fe3N (FeNC@C) acts as an efficient and stable catalyst for hydrogen peroxide (H2O2) activation, achieving a 90% removal rate of norfloxacin within 60 min.
Energetic MOF-derived Fe3C nanoparticles encased in N,S-codoped mesoporous pod-like carbon nanotubes for efficient oxygen reduction reaction
Authors: Liu Yang , Duan Xinde , Ge Fayuan , Wu Tingting , Zheng Hegen
Published: December 2024

A unique hybrid electrocatalyst consisting of Fe3C NPs and N, S-codoped mesoporous carbon nanotubes was manufactured by pyrolysis of a new energetic metal-organic framework, demonstrating excellent activity for oxygen reduction reaction.
An all-vanadium-based lithium-ion full battery with hierarchical yolk–shell structure electrodes
Authors: Zhang Jie , Zhu Kongjun , Kong Zhihan , Ji Dingwei , Guo Jun , Zhang Zheng , Wang Jing , Kang Yan , Liu Jinsong
Published: December 2024

An all-vanadium-based lithium-ion full battery is assembled with hierarchical micro–nano yolk–shell structures V2O5 and V2O3 as electrodes, which are obtained through a facile solvothermal method with heat treatment under different atmospheres.
Lignosulfonate as a versatile regulator for the mediated synthesis of Ag@AgCl nanocubes
Authors: Yin Lingyu , Yang Jian , Liu Liqin , Lu Bin , Lyu Xiaofeng , Cheng Zhengbai , Liu Hongbin , An Xingye
Published: December 2024

The remarkable catalytic activity, optical properties, and electrochemical behavior of nanomaterials based on noble metals (NM) are profoundly influenced by their physical characteristics, including particle size, morphology, and crystal structure.
Hierarchical chirality observed from chiral supramolecular assembling of racemic and enantiopure helicene derivatives on silica nanohelix surfaces
Authors: Hano Nanami , Zigon Nicolas , Kuppan Balamurugan , Sturm Ludmilla , Vanthuyne Nicolas , Pouget Emilie , Nlate Sylvain , Bock Harald , Durola Fabien , Avarvari Narcis , Oda Reiko
Published: December 2024

The combination of silica nanohelices and helicenes reveals different orientations of helicenes in helical supramolecular assemblies formed on silica surfaces, and the chiroptical signals were induced by helicene adsorption and helical organization.
Rational design of stable carbon nitride monolayer membranes for highly controllable CO2 capture and separation from CH4 and C2H2
Authors: Yong Yongliang , Cheng Zhuo , Guo Wentao , Hou Qihua , Liu Zhiyong , Huang Shaobo , Li Xinli , Ren Yongpeng
Published: December 2024

CO2 capture and separation from natural and fuel gas are important industrial issues that refer to the control of CO2 emissions and the purification of target gases.
Recent advances in the reactions of isatin-derived MBH carbonates for the synthesis of spirooxindoles
Authors: Zhao Kaiwen , Zhai Minghao , Zhang Lei , Meng Xiangtai
Published: December 2024

This review summarizes the reactions reported in recent years for the construction of the spirooxindole skeleton or C3 disubstituted oxindole derivatives using isatin-derived MBH carbonates.
Guanidinium-based ionic porous organic polymer as a propitious material for inordinate uptake of permanganate ions from water
Authors: Nandamol P. S. , Porel Mintu
Published: December 2024

Metal-based oxo anions are major contributors towards freshwater contamination.
Nanomolar detection of lurasidone hydrochloride in pharmaceutical formulations (Serodopamoun®) and spiked urine using a PVC/imprinted polymer/MWCNTs layer deposited onto polyaniline-coated screen-printed electrodes
Authors: El-Beshlawy Menna M. , Barhoum Ahmed , Abdel-Haleem Fatehy M.
Published: December 2024

This study developed potentiometric sensors for detecting lurasidone HCl (LSH), a vital drug for treating schizophrenia and bipolar I disorder, in pharmaceutical formulations and biological samples.
Microwave-assisted synthesis of base-modified fluorescent 1,4-dihydropyridine nucleosides: photophysical characterization and insights
Authors: Arora Aditi , Kumar Sumit , Maity Jyotirmoy , Singh Brajendra K.
Published: December 2024

A synthesis of a small library of fluorescent 1,4-dihydropyridine nucleoside analogues has been successfully carried out under solvent-free conditions via a one-pot three-component Hantzsch condensation reaction.
Rational design of a series of non-centrosymmetric antiperovskite and double antiperovskite borate fluorides
Authors: Chen Fuqiang , Wu Hongping , Hu Zhanggui , Wang Jiyang , Wu Yicheng , Yu Hongwei
Published: December 2024

New non-centrosymmetric antiperovskite (and double antiperovskite) borate-fluorides, [(M/Ba)2Ca]F[B2O5] (M = K, Rb) and [CsBaCa]F[B2O5] have been designed and synthesized. They all exhibit the interesting nonlinear optical properties.
Enhancing electrocatalytic hydrogen evolution via engineering unsaturated electronic structures in MoS2
Authors: Zhou Qingqing , Hu Hao , Chen Zhijie , Ren Xiao , Ma Ding
Published: December 2024

Focusing on the efficient electronic structures in MoS2. This review critically examines the origins of unsaturated electronic structures, strategies for their construction, and future directions for advancing this promising field.
Metathesis chemistry of inorganic cumulenes driven by B–O bond formation
Authors: Tang Jianqin , Hu Chenyang , Crumpton Agamemnon E. , Griffin Liam P. , Goicoechea Jose M. , Aldridge Simon
Published: December 2024

The reaction chemistry of an unprecedented ‘inorganic cumulene’ – featuring a five-atom BNBNB chain – towards CO (and related) multiple bonds is disclosed.
Electronic metal–support interaction in Pd/CoNi-hydroxides with enhanced CO adsorption for boosting CO2 methanation
Authors: Wu Yawei , Bhalothia Dinesh , Chou Jyh-Pin , Lee Guo-Wei , Hu Alice , Chen Tsan-Yao
Published: December 2024

Pd/CoNi-hydroxides with electron-rich Pd sites enhanced CO adsorption, thereby leading to good CH4 production.
Carbon emission reduction strategy planning and scheduling for transitioning process plants towards net-zero emissions
Authors: Lye Yuen Xiu , Chew Yick Eu , Foo Dominic C. Y. , How Bing Shen , Andiappan Viknesh
Published: December 2024

This work introduces a novel methodology to plan and schedule decarbonisation strategies to achieve net-zero emissions. By integrating graphical and mathematical approaches, it provides a user-friendly tool to determine the optimal timing for implementation across investment plans.
Enhanced hydrogen production and fuel conversion of an iron-based oxygen carrier in the chemical looping process by a small co-addition of CuO and NiO
Authors: Gao Zixiang , Hong Shaohuan , Yin Fan , Sun Liyan , Gong Feng , Fan Weiwei , Xiao Rui
Published: December 2024

Nearly complete fuel conversion and high H2 yield are obtained using Fe2O3–Al2O3 with a small co-addition of CuO and NiO.
Engineering a surface functionalized Pt@SnS2/Ti3C2Tx MXene sensor with humidity tolerance and high sensitivity at room temperature for NH3 detection
Authors: Ranjith Kugalur Shanmugam , Sonwal Sonam , Mohammadi Ali , Raju Ganji Seeta Rama , Huh Yun Suk , Han Young-Kyu
Published: December 2024

The design of hierarchical heterostructures that can detect volatile organic compounds (VOCs) at room temperature with good selectivity, sensitivity, and humidity tolerance is an intriguing and practically useful area of research.
Effect of potassium on the structure, characteristics and Cs sorption ability of porous materials in the system Na2O–B2O3–SiO2–GeO2
Authors: Koroleva Olga N. , Korobatova Nadezhda M.
Published: December 2024

Functional porous materials actively used as sorbents and membranes have complex microstructural morphologies that satisfy different requirements for industrial or medical purposes.
Engineering of redox-triggered polymeric lipid hybrid nanocarriers for selective drug delivery to cancer cells
Authors: Lokesh B. Siva , Ajmeera Suresh , Choudhary Rajat , Moharana Sanjaya Kumar , Purohit C. S. , Konkimalla V. Badireenath
Published: December 2024

Synthesis and fabrication of redox-switchable polymeric lipid hybrid nanocarriers that selectively deliver berberine and induce apoptosis in GSH-rich cancer cells while sparing healthy cells.
Jeroen Cornelissen retires as Editor-in-Chief
Authors: Cornelissen Jeroen
Published: December 2024

Jeroen Cornelissen reflects on his time as Editor-in-Chief for Journal of Materials Chemistry B and co-Editor-in-Chief for Materials Advances as he retires from his role.
Ferroelectric polarization-modulated two-dimensional homojunctions for enhanced nonvolatile multistate memory with self-powered optical readout capacity
Authors: Wang Yating , Hou Pengfei
Published: December 2024

A ferroelectric polarization-modulated two-dimensional homojunction, which has great potential for high-density data storage and offers an efficient means for self-powered optical readout, signifies a remarkable advance in storage technology.
All-inorganic lead-free double perovskite Cs2NalnCl6 for fiber-based optical temperature sensing for temperature and safety monitoring
Authors: Wang Xiao , Li Yanyan , Tang Haitao , Li Ruiming , Hao Xiaodi , Li Meng , Zhao Jiale , Yang Liyan , Chen Yu , Lin Qianqian , Li Mufang , Wang Dong
Published: December 2024

Double halide perovskites are widely utilized in photocatalysis, photovoltaics, and light emission owing to their nontoxicity and chemical stability.
Yolk-double shell structured bread-like Si@Z-700N@void@C nanocomposites as high stability anodes for lithium-ion batteries
Authors: Dong Weixiao , Sun Xiaojie , Zhang Tuo , Chen Ping
Published: December 2024

A yolk-double shell structured nanocomposite was used as an anode material for silicon-based lithium-ion batteries with excellent stability and cyclability.
Impact of wildfires on the drinking water catchment for the capital area of Iceland – a case study
Authors: Gunnarsdottir Maria J. , Tómasdóttir Sigrún , Örlygsson Olgeir , Andradóttir Hrund Ó. , Gardarsson Sigurdur M.
Published: December 2024

Climate change is leading to an increase in extreme weather events as drought causing wildfires in the Arctic, which can significantly affect both the quality and availability of drinking water.
Extending the accessibility of catalytic active sites through l-cysteine assisted sulfidation for promoting the hydrogen evolution reaction
Authors: Sagayaraj Prince J. J. , S. Kavinkumar , Oyama Keishi , Okibe Naoko , Kim Hyoung-il , Sekar Karthikeyan
Published: December 2024

We report a development in NiS catalysts using a simple hydrothermal method. The synthesized NiS exhibited a millerite phase and a pyrite phase, leading to improved HER (overpotential of 140 mV at −10 mA cm−2 and Tafel slope of 112.3 mV dec−1).
Palmitoylation and regulation of potassium-dependent sodium/calcium exchangers (NCKX)
Authors: Tao Ran , Robertson Alan D. , Fuller William , Gök Caglar
Published: December 2024

Cellular Ca2+ homeostasis is critical for normal cell physiology and is regulated by several mechanisms. Two major players in intracellular Ca2+ homeostasis in multiple tissues belong to the SLC8 (Na+/Ca2+ exchangers (NCXs); NCX1-3) and SLC24 (K+ dependent Na+/Ca2+ exchangers (NCKXs); NCKX1-5) families. It has been established that NCXs and NCKX4 are palmitoylated, and that palmitoylation promotes NCX1 inactivation. However, there is still little known about NCKXs’ palmitoylation. We found that (1) NCKX3 and NCKX5, but not NCKX1, are palmitoylated, (2) Cys to Ala mutation at position 467 for NCXK3 and 325 for NCKX5 notably diminished palmitoylation and (3) reduced palmitoylation enhanced NCKX3 activity. Our findings bring novel insights into NCKX1, NCKX3 and NCKX5 palmitoylation and establish palmitoylation as an endogenous regulator of NCKX3 activity, paving the way for investigations evaluating the role of palmitoylation in NCKX3 function in health and disease.
Motif‐based resiliency assessment for cyber‐physical power systems under various hazards
Authors: Binqadhi Hamed M. , AlMuhaini Mohammed M. , Poor H. Vincent , Flynn David , Huang Hao
Published: December 2024

Cyber‐physical power systems (CPPS) are integral to meeting society's demand for secure, sustainable, affordable and resilient critical networks and services. Given the convergence of decarbonising, heating, cooling, and transportation networks onto cyber‐physical power systems (CPPS), this takes on increased significance. This paper introduces an innovative approach to the open challenge of how we evaluate CPPS resilience, presenting the use of network motifs and Monte Carlo simulations. We demonstrate how our methodology enables a comprehensive analysis of CPPS by capturing the interdependence between cyber and physical networks and by accounting for inherent uncertainties in cyber and physical components. Specifically, this method incorporates the dynamic interplay between the physical and cyber networks, presenting a time‐dependent motif‐based resilience metric. This metric evaluates CPPS performance in maintaining critical loads during and after diverse extreme events in cyber and/or physical layers. The resilience status of the system is determined using the prevalence of 4‐node motifs within the system's network, offering valuable redundant paths for critical load supply. The study models a variety of natural events, including earthquakes, windstorms, and tornadoes, along with cyber‐attacks while accounting for their inherent uncertainties using Monte Carlo simulation. The proposed approach is demonstrated through two test CPPS, specifically the IEEE 14‐bus and IEEE 30‐bus test systems, affirming its effectiveness in quantifying CPPS resilience. By comprehensively addressing system dynamics, interdependencies, and uncertainties, the proposed technique advances our understanding of CPPS and supports resilient system design.