bluuebunny/crossref_metadata_2025 huggingface dataset:
Efikasi Afoxolaner terhadap Demodekosis General pada Anjing Berdasarkan Histopatologi Kulit
Authors: Christian Jeremy , Jayanti Putu Devi , Widyastuti Sri Kayati
Published: July 2023

Demodekosis adalah penyakit kulit yang paling umum ditemukan pada anjing, disebabkan oleh perkembangbiakkan tungau Demodex sp. yang berlebihan. Berdasarkan distribusi lesi, demodekosis dibagi menjadi lokal dan umum. Penelitian ini bertujuan untuk mengetahui efikasi dari Afoxolaner terhadap Demodekosis General pada anjing. Seekor anjing jantan ras campuran berumur 1,5 tahun dengan bobot 7,8 Kg datang ke Laboratorium Interna, Fakultas Kedokteran Hewan, Universitas Udayana, dengan keadaan anoreksia, lemas, dan kerontokan pada area wajah, sekitar telinga, leher, tungkai, badan samping, punggung, serta bagian ekstremitas. Pada pemeriksaan fisik ditemukan adanya alopesia, eritema di hampir seluruh tubuh, krusta, pustula di bagian medial ekstremitas kaudal. Anjing menunjukkan tingkat pruritus yang tinggi. Pemeriksaan hematologi rutin menunjukkan anjing mengalami anemia dan leukositosis. Diagnosa berdasarkan pemeriksaan mikroskopis dari kerokan mendalam atau deep skin scraping adalah Demodekosis. Prognosis pada kasus ini adalah fausta. Anjing kasus diterapi dengan menggunakan Afoxolaner (NexGard®), Azithromycin Dihydrate (10mg/kgBB, PO, q24h) dan Chlorpheniramine maleate (4mg/hari, PO, q12h) selama seminggu. Pemeriksaan histopatologi kulit sebelum diberikan obat ditemukan adanya potongan demodex pada folikel rambut, furunkulosis, infiltrasi sel radang pada stratum spinosum dan lapisan dermis, nekrosis disertai dengan adanya eksudat hemorrhagis, dilatasi folikel, dan perifolikulitis. Pasca terapi, hasil pemeriksaan histopatologi menunjukkan hasil yang baik, dengan tidak ditemukannya potongan tungau, ukuran folikel kembali normal, dan infiltrasi sel radang tidak terlihat pada perifolikel. Pada hari ke-10 terlihat keadaan anjing sudah membaik, hasil dari kerokan kulit menunjukkan berkurangnya jumlah tungau dalam satu lapang pandang. Pemberian Afoxolaner sebaiknya diberikan sebulan sekali selama tiga bulan untuk menghilangkan dan mencegah anjing terinfeksi tungau.
Efisiensi Penggunaan Enzim Taq Polymerase pada Pengujian Polymerase Chain Reaction
Authors: Anggreni Luh Dewi , Dewi Ni Made Ritha Krisna , Dewi Ni Putu Sutrisna , Mahardika I Gusti Ngurah Kade
Published: July 2023

Polymerase Chain Reaction (PCR) merupakan uji diagnostik yang sangat sensitif. Enzim Taq Polymerase merupakan salah satu komponen paling penting dalam pengujian Polymerase Chain Reaction (PCR). Enzim taq polymerase merupakan komponen yang harganya paling mahal. Penggunaan taq polymerase pada uji PCR kurang efisien. Untuk mengetahui efisiensi penggunaan enzim Taq Polymerase dan pada volume terkecil berapa masih dapat digunakan dalam metode pengujian PCR, maka dilakukanlah penelitian dengan membuat volume PCR lebih kecil (5µl, 10 µl, dan 25 µl) dari standard (50 µl). Tiga isolat swab hidung dan anus anjing terinfeksi Parvovirus diekstraksi menggunakan Kit DNA Purifikasi. Hasil ekstraksi dijadikan DNA Template pada pengujian PCR. Amplifikasi menggunakan mesin PCR Apply Biosistem Thermal Cycler. Visualisasi produk amplifikasi menggunakan elektroforesis gel agarose 1%. Hasil pengujian menunjukan bahwa volume PCR lebih kecil dari standard mampu memvisualisasikan produk PCR dengan baik. Pada PCR volume 5µl, tidak semua sampel teramplifikasi dengan baik. Sampel 1 dan 3 menunjukkan band tebal pada posisi sama dengan kontrol positif. Sedangkan sampel 2 tidak menunjukkan adanya band. Pada volume PCR (10µl, 25 µl dan 50µl) semua sampel teramplifikasi dengan baik. Sampel 1 dan 3 menunjukkan band tebal pada posisi sama dengan kontrol positif. Amplifikasi sampel 1 dan 3, gen memiliki panjang nukleotida 910bp (sesuai oligonukleotida), sedangkan sampel 2 juga menunjukkan adanya band tetapi posisinya lebih rendah dan tipis dari sampel 1, 3 dan kontrol positif. Adanya perbedaan tebal tipisnya band yang teramplifikasi disebabkan oleh perbedaan konsentrasi DNA hasil ekstraksi. Perbedaan tinggi band yang teramplifikasi pada sampel 2, berarti bahwa gen yang teramplifikasi bukan gen spesifik parvo. Simpulan penelitian ini adalah pada volume pengujian PCR dengan volume yang lebih kecil dari standard mampu memvisualisasikan gen DNA virus parvo dengan baik. Untuk mengefisienkan penggunaan enzim taq polymerase pada pengujian PCR, volume PCR 10µl dapat direkomendasikan sebagai protokol pengujian PCR untuk DNA Virus Parvo.
Pertumbuhan Pembuluh Darah pada Fase Kesembuhan Luka Insisi Tikus Wistar yang Ditetesi Antibiotika
Authors: Amalia Nabilah Rizky , Jayawardhita Anak Agung Gde , Samsuri Samsuri
Published: July 2023

Mekanisme pemberian tetes antibiotika terhadap kesembuhan luka insisi yang ditinjau dari jumlah pembuluh darah belum diketahui tingkat efektivitasnya. Untuk itu, penelitian ini bertujuan untuk mengetahui efektivitas pemberian tetes antibiotika terhadap jumlah pembuluh darah pada luka insisi tikus wistar (Rattus norvegicus). Penelitian ini menggunakan 24 ekor tikus wistar betina dengan berat badan masing-masing sekitar 150-200 gram. Setelah proses adaptasi selama satu minggu, selanjutnya dibuat luka insisi dengan panjang 1,5 cm dengan kedalaman sampai muskulus (0,5 mm) pada empat kelompok dengan pembagian kontrol (T0) diberikan NaCl fisiologis, perlakuan I (T1) tetes antibiotik oksitetrasiklin, perlakuan II (T2) tetes antibiotik amoxisillin, dan perlakuan III (T3) tetes antibiotik cefotaxime. Pada tiap kelompok tikus diberikan tetes antibiotika sebanyak tiga tetes atau sebanyak 0,15 ml. Setelah diberi perlakuan, kemudian dilakukan pengambilan sampel kulit tikus yang telah di insisi untuk dilakukan pemerikasaan histopatologi untuk diamati jumlah pembuluh darahnya. Hasil data perbedaan rerata jumlah pembuluh darah dianalisis menggunakan sidik ragam atau Analysis of Variant (ANOVA) dan apabila ditemukan hasil dengan perbedaan nyata maka dilanjutkan dengan uji Post Hoc Duncan. Hasil perbandingan rerata jumlah pembuluh darah pada keempat perlakuan secara berturut-turut yaitu 88.17 ± 77.78, 370.33 ± 277.14, 213.33 ± 41.44, dan 268.17 ±141.10. Hasil penelitian menunjukkan bahwa antibiotik dari golongan tetrasiklin memiliki rerata jumlah pembuluh darah paling tinggi dan memiliki kemampuan paling baik dalam meningkatkan proses angiogenesis.
Isolasi dan Identifikasi Bakteri pada Saliva Ular Sanca Batik di Pulau Bali
Authors: Shofi Muhammad Gus , Widyastuti Sri Kayati , Mahatmi Hapsari
Published: July 2023

Masalah satwa liar semakin tahun semakin meningkat, mulai dari kesehatan hingga lingkungan dan salah satunya yaitu ular. Semakin terganggunya habitat ular, isu gigitan ular menjadi masalah yang kian meningkat. Salah satu contohnya yaitu ular sanca batik yang berlokasi di Bali, bukan hanya manusia namun hewan lain juga dapat tergigit. Dalam rongga mulut ular terdapat bakteri yang dapat menginfeksi korban yang tergigit. Penelitian ini bertujuan untuk isolasi dan identifikasi bakteri pada rongga mulut ular sanca batik lokal bali yang hidup di alam. Penelitian ini dilakukan dengan rancangan observasional deskriptif. Sampel secara langsung diambil dari rongga mulut ular menggunakan cotton swab steril dan dimasukkan dalam media stuart agar lalu disimpan dalam Cooler box steril. Penelitian ini menggunakan 8 sampel saliva ular sanca batik lokal bali yang hidup di alam, yang di kultur menggunakan meliputi media transport Stuart Agar, media kultur Blood Agar, MacConkey, Eosin Methylen Blue Agar (EMBA) dan Salmonella Shigella Agar (SSA). media identifikasi bakteri Indol, Methyl red, Voges-Proskauer, sulfid indol motility, simmons citrate (IMViC) dan uji TSIA, uji fermentasi gula-gula (glukosa, laktosa, sukrosa, maltosa), dan uji pewarnaan Gram Crystal violet (Gram positif), Safranin (Gram negatif), bahan-bahan lain seperti alkohol 70%, aquades. Identfikasi sampel di laboratorium Klinik Satwa Sehat di Kota Malang. Hasil penelitian ini didapatkan bahwa 8 sampel saliva ular sanca batik lokal bali teridentifikasi 1 sampel (12,5%) ditemukan adanya bakteri Enterobacter sp., 2 sampel (25%) ditemukan adanya Serratia sp., Klebsiella sp. 1 sampel (12,5%), Salmonella sp. pada 2 sampel (25%), E. coli pada 1 sampel (12,5%) dan Proteus sp. pada 1 sampel (12,5%). Perlunya penelitian lebih lanjut tentang ditemukannya Salmonella sp. pada 25% dari sampel saliva ular sanca batik, dan juga penelitian lebih lanjut tentang ditemukanya Serratia sp. pada 25% dari sampel saliva ular.
Penilaian Penerapan Biosekuriti Pasca Wabah African Swine Fever pada Peternakan Babi di Kabupaten Kupang Nusa Tenggara Timur
Authors: Kurniawati Galih Shinta , Detha Annytha Ina Rohi , Kallau Novalino Harold Geoffrey
Published: July 2023

African swine fever (ASF) merupakan salah satu penyakit yang menyerang babi bersifat infeksius dan hemoragik yang disebabkan oleh virus DNA beruntai ganda, dalam famili Asfarviridae dan genus Asfivirus. Vaksin dan pengobatan untuk babi yang terinfeksi virus belum ditemukan membuat resiko ancaman bagi peternakan babi semakin besar sehingga biosekuriti menjadi tindakan yang sangat penting dalam mengurangi atau meminimalisir penyebaran serta pencegahan penyakit. Tujuan dari penelitian ini adalah mengidentifikasi jenis dan mengevaluasi teknik penerapan biosekuriti pada peternakan babi pasca wabah ASF di Kabupaten Kupang. Metode yang digunakan adalah metode cross sectional dan analisis deskriptif dengan melakukan wawancara observasional dan pengisian. Data penelitian ini disajikan dalam bentuk tabel pengolahan bobot dan tabel perbandingan jenis biosekuriti. Ada tiga jenis biosekuriti yaitu biosekuriti konseptual, struktural dan operasional. Bobot penerapan biosekuriti untuk ketiga jenis biosekuriti di enam peternakan mendapat kategori baik yaitu biosekuriti konseptual memiliki nilai bobot 128, biosekuriti struktural memiliki nilai bobot 261, dan biosekuriti operasional memiliki nilai bobot 204. Evaluasi dari nilai bobot ketiga jenis biosekuriti pada 6 peternakan babi masuk dalam penilaian kategori baik. Hal ini dibuktikan dengan diterapkannya ketiga jenis biosekuriti oleh keenam peternakan babi tersebut. Peneliti menyarankan peternak untuk meningkatkan penerapan biosekuriti, terutama dalam menangani jarak peternakan dengan pemukiman penduduk dengan cara membangun tembok batas peternakan yang lebih tinggi, membuat septic tank untuk penampungan limbah agar tidak mencemari lingkungan, penyediaan fasilitas sanitasi dan desinfeksi yaitu tempat dan sabun untuk mencuci tangan dan kaki, fasilitas toilet, serta pengadaan APD bagi para pekerja.
DERMAL CARCINOMA IN DOG AT ZOO CLINIC MAKASSAR
Authors: Andini Nurul Sulfi , Monica Wa Ode Santa , Deniaty Sri , Wahyuni Wahyuni , Gunawan I Wayan Nico Fajar
Published: July 2023

Dermal carcinoma or skin cancer in dog is a skin cancer consisting of various types of cancer which are included in it. The tumor appears as a solitary, non-encapsulated lump, generally hairless, and occasionally ulcerated, which moves freely. The diagnosis is generally made through microscopic examination of a sample of tumor cells (biopsy). Dermal carcinoma cases are cases that often occur in pets but reports of these cases are still rare especially in Indonesia. The purpose of writing is to describe clinical manifestations, clinical course, and case prognosis. This case report was obtained from the Zoo Clinic Makassar. A dog "Pororo" came with the owner with a temperature of 38.40 C, had an enlarged mass in the medial part of the radius dexter, encapsulated, with an estimated diameter of about 6 cm. Physical examination was carried out, followed by laboratory examination found that the WBC level was very high and anemia. Handling of cases in the form of removal of the tumor through surgery and followed by histopathological examination with Haematoxylin Eosin staining to determine tumor development stage, degree malignancy, prognosis and therapy. The results of histopathological examination stated that the cells found were not uniform and lead to metastasis. The diagnosis of Pororo disease is carcinoma dermatitis but the type is not clear because the primary cells have not been found. The prognosis is infausta, the presence of metastases worsens the prognosis of cases, and it is possible that new tumors will reappear after removal. Handling for similar cases should be done quickly and precisely so that the case prognosis can be better.
Polskie vs. czeskie lekcje zdalne. 3:0 dla Czechów
Authors: Pieniążek Marek
Published: July 2023

W artykule porównuję lekcje zdalne realizowane przez stacje telewizyjne w Polsce i w Czechach w czasie lockdownu. Sprawdzam, jak z wyzwaniami edukacyjnymi doby pandemii poradzili sobie medialni producenci i nauczyciele, weryfikuję wykorzystanie nowych technologii. Ogólna kultura cyfrowa i medialna twórców analizowanych zajęć wyraźnie wpływa na sposób ich mediatyzacji. Próbuję komparatystycznie uchwycić dominujące zasady metodyczne, metodologiczne oraz medialne w produkcjach polskich i czeskich. We wnioskach wskazuję na znaczące różnice w strukturze lekcji, wynikające z odmiennych kompetencji humanistycznych i medialnych ich twórców.
Influence of Remand Experiences on the Psychological Dispositions of Inmates in Selected Prisons within Kiambu County, Kenya
Authors: Patricia Abenyo  , Dr. Florence K’okul
Published: July 2023

The purpose of the study was to investigate the influence of the physical environment on the psychological dispositions of inmates in selected prisons within Kiambu County, Kenya. According to Fogel and Martin (2016), the psychological ramifications of stress associated with imprisonment are replicated in the same enhanced sentiments of hopelessness, loneliness, and anxiety that are experienced by offenders. According to Merrell and Walker (2018), the jail provides a clear and present hazard for worsening pre-existing mental diseases. In a jail, remand facilities are responsible for detaining a person for the shortest time that is practicable given the circumstances. The results could be significant to managing prison facilities holding pretrial inmates. This study may help prison institutions, police stations, probation stations, courts, prosecution, and other relevant stakeholders in the criminal justice system. This study might present some complementary strategies that may be used by therapists and counselors on inmates. This study may also offer some lasting solutions to challenges faced by prisoners in remand. The research used a descriptive research design to explore the phenomenon under consideration. The study was conducted in selected prisons within Kiambu County, Kenya. The population of the sample size was 315 respondents, which comprises 21.3% (0.213) of the whole population. According to the research, a sympathetic and supportive environment promotes prisoner relationships and healing characteristics like empathy, trust, and hope, Prisoners' physical, emotional, and spiritual needs are met by sympathetic warders, a stimulating environment where offenders have some personal control and greater responsibility for their health and well-being via increased independence, movement, and decision-making. The research also suggests that safe outdoor settings may be pleasant, helpful, and therapeutic diversionary activities. Good distractions may improve treatment and drug reduction in prisoners. Other important design components include personal space, particularly in open and suitable rooms, to avoid special and social congestion.
THE ROLE OF THE POM AGENCY IN CONTROLLING ANTIMICROBIAL RESISTANCE: IMPLEMENTATION OF HEALTH LAW NUMBER 36 OF 2009
Authors: Rahmawati Yulia
Published: July 2023

The global incidence of antimicrobial resistance (AMR) is escalating, with AMR now recognized as a significant health threat, ranking among the top ten global health issues. This paper addresses the critical need for effective AMR control and evaluates the government's efforts in line with Health Law Number 36 of 2009, focusing on the role of the POM Agency in managing AMR. Utilizing a normative research approach, this research involves a review of relevant literature and regulations, complemented by qualitative analysis. The findings indicate that the government has endeavored to meet the Health Law’s requirements by implementing a comprehensive, cross-sectoral AMR control strategy through Permenko No. 7/2021, which outlines the National Action Plan for Antimicrobial Control. Additionally, the Food and Drug Supervisory Agency has established AMR control policies through the Decree of the Head of BPOM No. HK.02.02.1.2.03.20.98 of 2020.
Alat Koreksi dan Rekontruksi Tulisan pada Dokumen Lama Bahasa Indonesia Berbasis Mini PC
Authors: Suwandi Rifki , Kasoep Werman , Destria Ramon Luthvi
Published: July 2023

In the digital era, preserving old documents to prevent damage is a significant challenge. One solution to this problem is to reconstruct damaged or lost documents using image processing and natural language processing technologies. This article discusses the design of a tool for correcting and reconstructing writing in old papers and documents that can be implemented on a mini PC. The tool uses state-of-the-art algorithms such as Convolutional Neural Network (CNN) for character recognition and Optical Character Recognition (OCR), as well as Image Inpainting and Sequence-to-Sequence (Seq2Seq) algorithms for document reconstruction. Test results show that this tool can recognize characters with high accuracy and reconstruct damaged or lost documents effectively.
Periurbano/agricultura periurbana: tres perspectivas: ecológica, social y territorial
Authors: Ochoa Céspedes Juan Camilo
Published: July 2023

El presente artículo tiene como fin analizar desde la perspectiva crítica, algunos alcances y desarrollos conceptuales del periurbano y la agricultura periurbana, el escrito abordará problemáticas relacionadas con la tensión territorial, consecuencia de la expansión acelerada de construcciones inmobiliarias que por cuenta del poco suelo urbano comienzan a ocupar zonas de periurbano, la discusión del articulo intentará poner en cuestión riesgos económicos, ambientales y sociales que esta expansión trae consigo, además, desde perspectivas sociales, ecológicas y territoriales se pondrán en evidencia tensiones y resistencias que están fuertemente cargadas de propaganda y que fomentan un tipo de vida atractiva y segregadora en tiempos de expansión neoliberal. En un primer momento el escrito desarrollará con algunos autores el concepto de periurbano y agricultura periurbana, en un segundo momento se realizará una conceptualización desde las tres perspectivas propuestas y, por último, se ilustrará con ejemplos esta problemática en el periurbano de la ciudad de Medellín y su área metropolitana.
Descripción de la distribución espacial de casos y defunciones por COVID-19 en la cuenca del Alto Cauca
Authors: Núñez Fernández David Fernando , Cuartas Arroyave Daniel Elías
Published: July 2023

El propósito de este artículo es caracterizar la relación entre los determinantes sociales de la salud y la distribución geográfica de casos de COVID-19 en los municipios de la Cuenca Alta del río Cauca. Para lograr este objetivo, se realizó un análisis exploratorio de datos espaciales, que incluyó tasas de mortalidad y casos por COVID-19, así como un análisis temporal de la difusión espacial que comprende el período desde 6 de marzo de 2020 hasta el 26 de junio de 2021, todo a partir de datos del Instituto Nacional de Salud (INS). Los resultados muestran que la concentración de casos y defunciones por COVID-19, junto con los determinantes sociales de la salud, tienden a concentrarse en las áreas más pobladas, como la zona del viejo Caldas, el centro del Valle del Cauca, la zona metropolitana de Cali y el sur del Cauca. Además, se concluye que la concentración de municipios es resultado de la relación directa entre los determinantes sociales de la salud y la incidencia de casos de COVID-19.
Fraseología y literatura: el parásito en las comedias de Plauto
Authors:   Universidad de La Laguna (España), Lojendio Quintero María del Pilar
Published: July 2023

The works of Plautus are a boundless source of knowledge that allows to explore the many resources offered by the Latin language. Among these resources, Phraseology stands out, given the close relationship between Plautus’s comedies and everyday life. The characters in the plays belong to very different social and economic classes, and these differences are also reflected in the language in general and in Phraseology in particular. Following this line of thought, I analyze the phraseological units that Plautus puts in the mouth of the character of the parasite in order to study the close relationship between Phraseology and the depiction of characters.
Unidades fraseológicas derivadas de פָנִםי / facĭes en los romanceamientos del Génesis (una aproximación cualitativa)
Authors:   Universidad de Granada (España), Porcel Bueno David
Published: July 2023

The use of fixed expressions with somatic elements is one of the characteristics that has drawn the most attention of scholars of biblical Latin. Taking into consideration that many of these locutions are copies from the Hebrew, this paper studies the importance that the medieval translations of the Hebrew Bible and the Vulgate had for the creation and development of these adverbial schemes formed by one, or even two, initial prepositions plus a noun that functions as the nucleus. On this occasion, the book of Genesis is analyzed in depth, and special attention is paid to fixed expressions and free combinations derived from the nouns ניםִ פָ / facĭes. Their discursive functions and the main patterns of morphosyntactic change are analyzed, with special emphasis on the semantic differences that they manifest in the transition from Hebrew to Spanish. To carry out this study, the Medieval Bible corpus has been used: a diachronic corpus that allows to consult concurrently all the medieval biblical versions in Spanish that have been preserved to this day.
Tradiciones e hitos históricos en la codificación lingüística de las construcciones comparativas fraseológicas
Authors:   Universidad de Granada (España), Montoro del Arco Esteban Tomás
Published: July 2023

Phraseological comparative constructions (PCC) such as más feo que Picio or beber como un cosaco have been included in all the classifications of idioms that have been posed since the second half of the 20th century, the moment when phraseology was established as a scientific discipline within Linguistics. However, these idioms present a considerable theoretical vagueness, as a consequence of the complex historical codification of a concept in which very different areas are involved (rhetoric, literature, folklore, or grammar). In this work, the main historical milestones in the treatment of this phenomenon are described: from the consideration of the simile within ecclesiastical rhetoric to the modern postulates of the 20th century, also including its grammatization in the grammatical treatises for foreigners of the 16th and 17th centuries, or the great compilations of the international movement of Folklore since the second half of the 19th century. A double objective is pursued: a) to contribute to a better knowledge of the so-called Spanish phraseography; and b) to use the historiographical argument as a basis to achieve a greater characterization of comparative phraseological constructions nowadays.
¡Lo que yo de cura! El «antiprototipo» en las construcciones comparativas intensificadoras desde un punto de vista construccionista
Authors:   Universidade de Santiago de Compostela (España), Mellado Blanco Carmen
Published: July 2023

This paper analyzes the intesifying comparative construction [SN VTENER de ADJ lo (mismo) que X (de Y)]: ‘not being ADJ at all’, which allows for the creation of structures such as «Pues te digo: esos jóvenes tienen de solidario lo que yo de cura». In such a construction, intensification is achieved by means of a semantic and pragmatic incongruence between the slots X and Y (as in the example: yo vs. cura), whereby the standard of comparison Y (cura) becomes an «antiprototype», as opposed to what occurs in most stereotyped comparisons (e. g. dormir como un lirón). Within the framework of Construction Grammar, the main goal is to demonstrate, through corpus analysis (esTenTen18 corpus), that the antiprototype is not fixed at the lexical level, but through a cognitive core. A qualitative study of the slot Y of the standard of comparison is carried out in order to find out which cognitive clusters promote pragmatic incongruence, as well as to explore how the maximum level of extravagance is reached.
Colocaciones sensoriales: el tacto y el dominio del intelecto
Authors:   Universidad de Alcalá (España), Oliveira Silva Maria Eugênia Olímpio de
Published: July 2023

In this paper, I ponder on the connection between the sense of touch, generally associated with the expression of emotion, and some mental activities related to the notions of knowledge or intellection. This connection has been previously considered in different contexts: Cultural History of the Senses, Philosophy, Cognitive Linguistics and, in particular, Sensory Linguistics. The main objective is to find out how this correlation manifests linguistically in Spanish producing multi-word lexical units, specifically collocations. I thus try to determine which lexical units linked to touch make up the structure of these collocations and what types of tactile properties are related to these units. Considering the data extracted from the combinatory dictionary REDES, the existence of «tactile» collocations representing the materialization of the perception metaphor understanding is touching has been verified. The conclusion reached is that the sense of touch is a productive source domain in the Spanish language, becoming the basis for the creation of a large number of collocations linked to the domain of meta intellect.
Fraseología aplicada a la adquisición del español como lengua extranjera /
Authors:   Universidad de La Laguna (España), Cano Ginés Antonio , Arroyo Martínez Laura ,   Universidad Rey Juan Carlos (España)
Published: July 2023

This work belongs to the research field of Phraseodidactics applied to the teaching of Spanish as a foreign language (ELE). The objectives of our research are: to present a typology proposal for the different phraseological units, to point out what the selection criteria should be to showcase these lexical units in the classroom, to provide basic guidelines for their teaching, and to present a typology of activities based on the strategies of learning that students must develop, together with the temporal phases through which these structures are learned. As conclusions of the research, it is shown that it is necessary to work on three preferential lines: the data dump of the phraseological units found in the Curricular Plan of the Cervantes Institute, the elaboration of their didactic classification, and the creation of didactic units. Likewise, the creation of specific didactic units for learning about this type of lexical units is considered to be an ensuing task.
Homozygous delta beta-thalassemia: A rare case report
Authors: Debbarma Sneha , Bhamre Nilesh , Shetty Prashant , Pawar Ravikiran Narayansing
Published: July 2023

Delta Beta (δβ) thalassemia is a rare autosomal recessive hemoglobinopathy. This is caused by either reduced production of δ and β genes (heterozygous state) or complete absence (homozygous state). High-performance liquid chromatography (HPLC) is an important screening and diagnostic tool, to be supported by molecular data and parental studies. A 40-year-old male (propositus), with mild anemia presented in the outpatient department. There were no other definitive causes of anemia with adequate nutritional status and no response after the treatment with nutritional supplements. HPLC was advised to look for any qualitative/quantitative defects. HPLC findings reveal 96% fetal hemoglobin (HbF), a very small quantity of adult hemoglobin (HbA), and an absent HbA2. In view of this data, followed up with parental studies. Both parents had elevated HbF and similar grades of anemia. These supported the presence of a heterozygous state of δβ-thalassemia in parents and homozygous δβ thalassemia in propositus. In δβ-thalassemia, there is a deletion of the δ and β genes on Chromosome 11. Expression of the gamma gene increases to compensate, causing increased production of gamma globulin for HbF (α2 β2). On HPLC or electrophoresis, heterozygosity shows as normal HbA2 and elevated HbF, and as absent HbA2 with almost 100% HbF for homozygous individuals. Screening of hemoglobinopathies by HPLC is that can be further subjected to parental screening for a more definitive diagnosis and narrow down the differentials as compared to molecular testing considering the cost, limited availability, and higher turnaround time.
Clinical features and surgical treatment of combination of pronator teres syndrome and carpal tunnel syndrome
Authors: Chyrka Iurii L. , Lemeshov Oleksandr S.
Published: July 2023

Objective: To determine the effectiveness of surgical interventions aimed at decompression of the median nerve (MN) in the carpal tunnel and pronator teres canal, in combination with carpal tunnel syndrome (CTS) and pronator teres syndrome (PTS).
Materials and methods: The results of surgical treatment of patients with a combination of CTS and PTS were analyzed, a total of 20 observations. The analysis of the results was evaluated according to: the Boston Questionnaire (BCTQ), namely, symptoms severity scale - SSS (minimum 1 point, maximum 5 points) and functional severity scale - FSS (minimum 1 point, maximum 5 points), the Bishop Score, visual analogue scale (VAS).
Results: All operated patients (100%) experienced a significant regression of the main manifestations of the disease on the first day after the operation. Paresthesia in the fingers of the hand decreased, the sensitivity in the MN dermatome improved significantly, and sleep improved. The average indicators after surgery on symptoms severity scale (SSS) were 1.3 points, on functional severity scale (FSS) - 1.4 points, visual analogue scale - 2 points. The assessment of treatment results according to the Bishop Score in the postoperative period, that is, at the time of discharge (3 days after surgery), was an average of 10 points.
Conclusions: Decompression of the MN in the area of the carpal tunnel and pronator teres is an effective method of treatment for the combination of CTS and PTS. A positive effect in the form of a regression of pain syndrome, sensitivity disorders and an increase in strength in the hand is observed already in the early postoperative period. Scores on BCTQ and VAS improve by more than 50%.
Comparative Analysis of the Krasnyy Most and Early Volosovo Ceramics of the Mari Volga Region
Authors: Андреева О.В. , Шалапинин А.А.
Published: July 2023

В статье представлены результаты сравнительного анализа керамики красномостовского типа и волосовской культуры территории Среднего Поволжья. В ходе типологического и технико-технологического анализа было выявлено, что между красномостовской и ранней волосовской керамикой наблюдается сходство в формах сосудов, орнаментации, отборе сырья и массовом применении органических растворов. Но наряду с этим между рассматриваемыми керамическими комплексами существует и ряд отличий, выраженных в разнообразии отдельных элементов орнаментации, формах венчиков, разном представлении населения о составе формовочной массы.

He paper reports on the results of comparative analysis of the Krasnyy Most type of ceramics and the Volosovo ceramics originating from the Middle Volga region. The typological and technical/technological analyses point to similarities between the Krasnyy Most and the Early Volosovo ceramics with regard to the form of vessels, decoration, selection of raw material and application of organic solutions. However, there are a number of differences between these assemblages such as specific elements of decoration, forms of rims, different concepts of the clay composition developed by the populations.
Shoe Heelplates from Excavations in the Moscow Kremlin
Authors: Осипов Д.О. , Коваль В.Ю. , Смирнов А.Н.
Published: July 2023

При раскопках, проводившихся в 2019-2021 гг. Институтом археологии РАН на территории Большого сквера Московского Кремля, собрана репрезентативная коллекция железных обувных подковок, отбиравшихся из хорошо датированных слоев. Благодаря этому возможно уточнить время появления в Москве и бытования различных типов этой категории археологических находок, процесса их морфологических изменений. Представлен краткий историографический обзор группировки обувных подковок и предложена уточненная классификация, позволяющая проводить статистическую фиксацию массовых находок таких изделий. Поставлен вопрос об источнике восприятия в Восточной Европе моды на обувные подковки.

The excavations conducted by the Institute of Archaeology, RAS, in the Large Garden Square of the Moscow Kremlin in 2019-2021 yielded a representative assemblage of iron shoe heelplates selected from reliably dated layers. This assemblage offers an opportunity to specify the period when various types of this category of archaeological finds appeared in Moscow and clarify the process of their morphological changes. The paper provides a historiographical overview of the heelplate groups and proposes a clarified classification that will help to document frequent finds of such items statistically. The paper also raises an issue regarding the origin of fashion for shoe heelplates in Eastern Europe.
Medieval Fish Leather Items in Pereyaslavl Ryazanskiy
Authors: Фатюнина О.А.
Published: July 2023

Статья посвящена редким археологическим находкам изделий из рыбьей кожи, обнаруженным на Введенском раскопе Переяславля Рязанского в культурных напластованиях второй половины XV в. Традиция использования рыбьих кож коренными малочисленными народами хорошо известна по данным этнографии, тогда как среди средневековых археологических материалов в Центральной России находки рыбьих кож известны не были. Несмотря на фрагментарность изделий, изучение под микроскопом позволило предположить их функциональное назначение.

The paper is dedicated to rare archaeological finds of items made from fish leather that have been discovered in the Vvedenskiy excavation pit of Pereyaslavl Ryazanskiy in the cultural layers dating to the second half of the 15th century. The tradition of using fish leather by indigenous small peoples is well known from ethnographic evidence whereas in Central Russia finds of fish leather among archaeological materials have been unknown. Despite a fragmentary state of the items, the microscopic examination suggests their functional purpose.
Textile from the Early Medieval Cemeteries in the Crimea
Authors: Строков А.А. , Камелина Г.А. , Мамонова А.А.
Published: July 2023

Статья посвящена изучению текстиля из могильников Чуфут-Кале, Суук-Су и Скалистинский, хранящегося в Государственном историческом музее (ГИМ). В основном это мелкие фрагменты, сохранившиеся на металлических предметах, прежде всего деталях костюма. Несколько фрагментов из Суук-Су были достаточно большого размера и сохранили свою изначальную структуру, а также проколы, след от сгиба, краску, что может говорить о том, что это было какое-то текстильное изделие. Технологический анализ показал, что чаще для производства ткани использовали растительное волокно, но иногда применялась и шерсть. Все фрагменты изготовлены в одной технике - имеют Z-крутку, полотняное переплетение, плотность в среднем 14-16 нитей / кв. см. Радиоуглеродное датирование фрагмента из Суук-Су позволяет отнести этот комплекс ко второй половине VI в. Анализ соотношения изотопов стронция в этом же образце и в фоновых показателях с территории Крыма, а также результаты технологического анализа позволяют предполагать использование древними ткачами местного сырья.

This paper explores textile items from the Chufut-Kale, Suuk-Su and Skalistinsky cemeteries that form part of the State Historical Museum collections. In most cases, small fragments adhering to metallic items, in particular, details of clothing, have been preserved. Some fragments from Suuk-Su were rather large, they have retained their initial structure, perforation, fold marks as well as dye suggesting that they are from textile items. The technological analysis shows that plant fibers were more commonly used for making fabrics, however, wool was also used. All fragments are made with the use of the same technology: they have a Z-twist, plain weave, with the average thread count being 14-16 threads per cm. Radiocarbon dating of the Suuk-Su fragment refers this assemblage to the second half of the 6th century. The analysis of the strontium stable isotope ratio in this sample as well as the reference sample datasets from the Crimea and the technological analysis imply that ancient weavers used local raw materials.
Paleoecology and Land Use Patterns Based on the Study of Cultural Layers and a Buried Soil of the Tula Kremlin
Authors: Хохлова О.С. , Макеев А.О. , Энговатова А.В. , Кузнецова Е.А. , Гольева А.А.
Published: July 2023

Изучение свойств палеопочвы и культурных слоев разреза Тульского кремля позволило провести палеоэкологическую реконструкцию этапов преобразования ландшафта, охарактеризовать ранние стадии человеческой деятельности на данной территории, а также объяснить расположенность крупного культурного и хозяйственного центра позднего Средневековья на низком гипсометрическом уровне в непосредственной близости от уреза реки Упы. Были изучены морфологические и физико-химические характеристики погребенной почвы и культурных слоев, рассчитаны геохимические коэффициенты, а также проведены микроморфологический и микробиоморфный анализы. Показано, что участок, на котором расположена крепость, никогда не заливался рекой. Почва на покровных (лёссовидных) отложениях характеризуется строением профиля, типичным для окружающих водораздельных пространств, в ней признаки оглеения (переувлажнения) выражены слабо или не выражены вовсе. Перед возведением укреплений на данном участке недолго была пашня или огород. В культурных слоях за счет привноса различных строительных материалов отмечается накопление веществ и элементов, не свойственных окружающим почвам. Педогенные признаки, сохранившиеся в культурных слоях, позволили реконструировать динамику палеоклиматических условий в разные периоды строительства или перестройки кремля. Культурный слой 1 (XVII-XVIII вв.) формировался в сравнительно влажных климатических условиях, а во время формирования культурного слоя 2 (XVI-XVII вв.) было немного суше, но и холоднее.

The study of the buried soil and cultural layers in the Tula Kremlin allowed providing paleoenvironmental reconstruction for the period between 16th century and present, to reveal the early land use practices, and also to explain the location of a large cultural and economic center of the late Middle Ages at a low hypsometric level in the immediate vicinity of the edge of the Upa River. The research is based on the morphology, micromorphology and analytical features of the buried soil and cultural layers, including geochemical ratios and phytolith assemblages. It is shown that the site where the fortress is located has never been flooded with a river. The soil is formed in mantle (loesslike) loams and is similar to the soils of the surrounding uplands; gleying (waterlogging) features in it are nearly absent. In a short period before the erection of fortifications, this site was used for arable land or vegetable garden. The cultural layers show accumulation of artifacts and elements that are foreign to the soils of the area. Pedogenic features preserved in the cultural layers made it possible to reconstruct the paleoclimatic dynamics in different periods of the Kremlin's construction or rebuilding. Thus, cultural layer 1 (17th-18th centuries) was formed in relatively humid climate, and during formation of cultural layer 2 (16th-17th centuries) it was slightly drier, but also colder than today.
«Shaft Straighteners» in North Mesopotamia during the Neolithic . .
Authors: Усачева И.В. , Корниенко Т.В.
Published: July 2023

В эпипалеолите на территории Юго-Западной Азии появляются желобчатые камни особого типа, так называемые «выпрямители древков», которые в докерамическом неолите получают широкое распространение, а к концу керамического неолита практически полностью исчезают. На основе хронологического, картографического, морфологического, контекстного и образно-композиционного анализа данных в работе определены время и места появления, ареал и динамика распространения, региональные особенности нахождения и оформления «выпрямителей древков» Северной Месопотамии в эпоху неолита.

During the Epipaleolithic period grooved stones of a special type, the so called «shaft straighteners» appeared in Southwest Asia. They were widespread during the Pre-Pottery Neolithic period whereas by the end of the Ceramic Neolithic they practically went out of use. Based on the chronological, cartographical, morphological as well as figurative and compositional analysis, the paper describes the time and the place where such objects appeared, the area and changes over the time in their dissemination, local and regional distinctive traits of occurrence and decoration of «shaft straighteners» in Northern Mesopotamia during the Neolithic.
Preserve the existence of balala’ tamakng tradition of dayak ethnic to maintain the national identity of indonesia
Authors: Ramadhan Iwan , Imran Imran , Hardiansyah Muhammad Agus , Chappel Cary , Firmansyah Haris
Published: July 2023

The Balala' Tamakng tradition is a tradition of abstinence that is still believed and carried out by the Dayak ethnic community in Sungai Ambawang District, Kubu Raya Regency. This study aims to determine the procession of the Balala' Tamakng tradition, the symbolic meaning of the Balala' Tamakng tradition and efforts to maintain the Balala' Tamakng tradition in the era of globalization in an effort to maintain national identity. The high flow of globalization, indirectly, has gradually faded the traditions of today's traditional society. This research seeks to discover the efforts of the Dayak ethnic community in Sungai Ambawang District in preserving the Balala' Tamakng tradition in maintaining national identity amidst the influence of globalization. The research method used is descriptive research using a qualitative approach. The data collection technique that will be used is the process of observation, in-depth interviews, and documentation. The research results in a state that the Balala' Tamakng tradition is carried out through the process of the ritual. As for the meaning or meaning of the Balala' Tamakng tradition, it is abstinence for a full day with the condition that you are not allowed to set foot out of the house, not shout or make noise in the house. In this era of globalization, efforts to maintain the Balala' Tamakng tradition are made by strengthening national identity and by sharing these ritual activities through social media
Copper-Catalyzed Sulfimidations of Benzylic C(sp3)-H Bonds
Authors: Lu Xunbo , Huang Guoling
Published: July 2023

In this study, we elucidate a novel strategy for benzylic C(sp3)-H activation, enabling the construction of C-S bonds through a copper-catalyzed sulfimidation process. Leveraging readily available methylarenes as substrates, our methodology offers an economically efficient and highly viable approach. The scalability of the reaction, its applicability to a broad range of substrates, and significant application value underscore its potential and transformative impact in the realm of synthetic organic chemistry.
Emergence of Anionic Counterparts of Divalent Metal Salts as the Fine-Tuners of Alginate Hydrogel Properties for Tissue Engineering and Drug Delivery Applications
Authors: Dash Subhasis , Gutti Pavan , Behera Birendra , Mishra Debasish
Published: July 2023

The role of anionic counter ions of divalent metal salts in alginate gelation and hydrogel properties was thoroughly investigated. Three anions were selected from the Hofmeister series viz. sulphates, acetates and chlorides paired in all permutations and combinations with calcium, zinc and copper divalent metals. Spectroscopic analysis revealed the presence of anions and their interaction with the metal atoms post-gelation. Data showed gelation time and other hydrogel properties were mostly governed by the cations. However, subtle yet significant variations in viscoelastic, water-uptake, drug-release and cytocompatibility properties were anion dependent in a cationic group. Computational modelling study showed metal-anion-alginate configurations were energetically more stable than metal-alginate models. The in vitro and in silico studies conclude that acetate anions precede the chlorides in the drug-delivery, swelling, and cytocompatibility fronts, followed by sulphate anions in each cationic group. Overall, the data provided affirmation that anions are integral part of the metal-alginate complex. Furthermore, anions offer a novel option to further fine-tune the properties of alginate hydrogels for tissue engineering and drug delivery applications. Moreover, extensive exploration of this novel avenue would enhance the usability of alginate polymers in pharma, environmental, biomedical and food industries.
Exploring the Mechanism of the Electrochemical Polymerization of CO2 to hard carbon over CeO2 (110)
Authors: Keller Florian , Döhn Johannes , Gross Axel , Busch Michael
Published: July 2023

Conversion of CO2 to hard carbon is an interesting technology for the removal of carbon dioxide from the atmosphere. Recently, it was shown that CeO2 can selectively catalyse this reaction but we still lack information regarding the reaction mechanism. Using density functional theory (DFT) modelling we explore possible reaction mechanisms that allow for the polymerization of CO2. According to our computations the reaction is initialized by the adsorption of CO2 in an oxygen vacancy. Owing to the rich defect chemistry of ceria a large number of suitable sites are available at the surface. C-C bond formation is achieved through an aldol condensation type mechanism which comprises the electrochemical elimination of water to form a carbene. This carbene then performs a nucleophilic attack on CO2 . The reaction mechanism possesses significant similarities to the corresponding reaction in synthetic organic chemistry. Since the mechanism is completely generic it allows for all relevant steps of the formation of hard carbon like chain growth, chain linkage and the formation of side chains or aromatic rings. Surprisingly, ceria mainly serves as an anchor for CO2 in an oxygen vacancy while all other subsequent reaction steps are almost completely independent from the catalyst. These insights are important for the development of novel catalysts for CO2 reduction and may also lead to new reactions for the electrosynthesis of organic molecules.
Distraction Aids in Pediatric Dentistry: An Overview
Authors: Byndoor Ulka , V Soundarya , Sunil Raj N Dr. , A Nandan , C Anitha
Published: July 2023

Distraction is a method where attention of an individual or a group is altered from the preferred vicinity of recognition through blockading or diminishing the reception of preferred information. These aids circuitously have an impact on positive behavior and decrease the fear at some stage during dental visits. There are unique strategies such as providing a short break prior to superior behavioral strategies which can be effective during dental extraction. This overview emphasizes on unique distraction aids used in pediatric dental practice.