bluuebunny/crossref_metadata_2025 huggingface dataset:
Table S1 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: March 2023

Cox proportional hazards regression for overall survival (105 neuroblastomas)
Supplementary Figure S1 from Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals
Authors: Hofmann Jonathan N. , Birmann Brenda M. , Teras Lauren R. , Pfeiffer Ruth M. , Wang Ye , Albanes Demetrius , Baris Dalsu , Colditz Graham A. , De Roos Anneclaire J. , Giles Graham G. , Hosgood H. Dean , Lan Qing , Landgren Ola , Liao Linda M. , Rothman Nathaniel , Weinstein Stephanie J. , Pollak Michael N. , Neuhouser Marian L. , Purdue Mark P.
Published: March 2023

Risk of MM in relation to circulating total adiponectin levels estimated using a restricted cubic spline regression model with 4 knots.
Supplemental Materials and Methods from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

Supplemental Materials and Methods
Supplemental Figure Legend from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

Supplemental Figure Legend
Supplemental Figure 6 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

Effect of knocking down ODC expression in HCT116 colon cancer cells. Colon cancer cells were stably transfected with shMock or shODC. Confirmation of (A, upper left panel) knockdown of ODC protein expression by Western blot; (A, upper right panel) knockdown of ODC transcription level by RT-PCR; and (A, lower panel) knockdown of ODC activity measured as release of L-[1-C14] ornithine. (B) The effect of knocking down ODC expression on anchorage-independent HCT116 colon cancer cell growth. Colonies were counted using a microscope and the Image-Pro PLUS (v6) computer software program. (C) The effect of knocking down ODC expression on HCT116 colon cancer cell growth was analyzed over 1, 2 or 3 days using the MTS assay. (D) The effect of knocking down ODC expression on AP-1 reporter activity was measured using substrates in the reporter assay system. For A-D, data are represented as mean values {plus minus} S.D. of triplicate experiments and the asterisk (*) indicates a significant difference (p < 0.05) versus shMock cells. (E) Effect of knocking down ODC expression on the phosphorylation of ERK1/2 and RSK was determined by Western blotting. Similar results were observed from two independent experiments and representative blots are shown.
Supplementary Materials and Methods from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: March 2023

Description of additional methods and procedures used in the study
Supplemental Figure 1 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

Effect of herbacetin or kaempferol on ODC activity. (A) Herbacetin or (B) kaempferol was modeled as an allosteric inhibitor with the ODC crystal structure. (C) The effect of herbacetin or kaempferol (upper panels) on ODC activity (lower panel) was assessed using a human ODC recombinant protein. Each reaction was incubated at 37{degree sign}C for 1 h and ODC activity was measured as the release of CO2 from L-[1-C14] ornithine. Data are represented as mean values {plus minus} S.D. of triplicate experiments. The asterisk (*) indicates a significant decrease (p < 0.05) in ODC activity between herbacetin-treated samples compared to untreated or kaempferol-treated samples.
Supplementary Table S1 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: March 2023

Association of MALAT1 expression with clinical parameters in RCC patients.
Supplementary Figure S2 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: March 2023

Schematic representation of ChIP primers located in the promoter of the E-Cadherin gene.
Supplementary Figure 2 from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: March 2023

Supplementary Figure 2. miR-892b expression is downregulated in breast cancer and inversely correlates with breast cancer progression and poor prognosis.
Supplementary Tables 1 through 3 from FOXD1–ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells
Authors: Cheng Peng , Wang Jia , Waghmare Indrayani , Sartini Stefania , Coviello Vito , Zhang Zhuo , Kim Sung-Hak , Mohyeldin Ahmed , Pavlyukov Marat S. , Minata Mutsuko , Valentim Claudia L.L. , Chhipa Rishi Raj , Bhat Krishna P.L. , Dasgupta Biplab , La Motta Concettina , Kango-Singh Madhuri , Nakano Ichiro
Published: March 2023

Supplementary Table S1. Cohort demographics of 83, 84, 157, 1016, 28, 711 and 267 glioma spheres. Supplementary Table S2. STR analysis result of 83, 84, 157, 1016, 28, 711 and 267 glioma spheres. Supplementary Table S3. Physical chemical properties of GA11 and GA23, determined by BIOVIA Discovery Studio 4.5.
Supplementary Methods and Materials from FOXD1–ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells
Authors: Cheng Peng , Wang Jia , Waghmare Indrayani , Sartini Stefania , Coviello Vito , Zhang Zhuo , Kim Sung-Hak , Mohyeldin Ahmed , Pavlyukov Marat S. , Minata Mutsuko , Valentim Claudia L.L. , Chhipa Rishi Raj , Bhat Krishna P.L. , Dasgupta Biplab , La Motta Concettina , Kango-Singh Madhuri , Nakano Ichiro
Published: March 2023

Supplementary methods and materials
Supplementary figure legends from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: March 2023

This file contains the legends for the six supplementary figures.
Supplementary Materials and Methods from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: March 2023

This file contains additional information regarding the methods used in the manuscript, including shRNA sequences, peptide and antibody information, and details about analysis methods.
Figure S7 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: March 2023

Growth of tumors formed by CW9019-Luc aRMS cells transplanted subcutaneously to athymic nude mice.
Supplementary figure legends from Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer
Authors: Regan Anderson Tarah M. , Ma Shi Hong , Raj Ganesh V. , Cidlowski John A. , Helle Taylor M. , Knutson Todd P. , Krutilina Raisa I. , Seagroves Tiffany N. , Lange Carol A.
Published: March 2023

Figure legends for supplementary figures 1 and 2.
Supplementary Figure Legends from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Authors: Lawson Campbell D. , Fan Cheng , Mitin Natalia , Baker Nicole M. , George Samuel D. , Graham David M. , Perou Charles M. , Burridge Keith , Der Channing J. , Rossman Kent L.
Published: March 2023

Figure Legends for Supplementary Figures S1-S4
Supplementary Mov. 1 from Tumor Cell Invasion Can Be Blocked by Modulators of Collagen Fibril Alignment That Control Assembly of the Extracellular Matrix
Authors: Grossman Moran , Ben-Chetrit Nir , Zhuravlev Alina , Afik Ran , Bassat Elad , Solomonov Inna , Yarden Yosef , Sagi Irit
Published: March 2023

Supplementary Mov. 1 from Tumor Cell Invasion Can Be Blocked by Modulators of Collagen Fibril Alignment That Control Assembly of the Extracellular Matrix
Supplemental Figures S1-4 from Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins
Authors: Nilsson Lisa M. , Green Lydia C. , Muralidharan Somsundar Veppil , Demir Dağsu , Welin Martin , Bhadury Joydeep , Logan Derek T. , Walse Björn , Nilsson Jonas A.
Published: March 2023

Figure S1: Molecular modelling and structure determination by X ray crystallography. Expanded data related to Figure 1B. Figure S2-S3: Ingenuity Pathway analyses of microarray data. Expanded analyses related to Figure 4 and Supplemental dataset 1. Figure S4: Gene-set enrichment analyses of microarray data. Expanded analyses related to Figure 4 and Supplemental dataset 1.
Supplemental Figure legends from CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1–Dependent IGF-1 Signaling
Authors: Sun Haibo , Lin De-Chen , Cao Qi , Guo Xiao , Marijon Helene , Zhao Zhiqiang , Gery Sigal , Xu Liang , Yang Henry , Pang Brendan , Lee Victor Kwan Min , Lim Huey Jin , Doan Ngan , Said Jonathan W. , Chu Peiguo , Mayakonda Anand , Thomas Tom , Forscher Charles , Baloglu Erkan , Shacham Sharon , Rajalingam Raja , Koeffler H. Phillip
Published: March 2023

Figure legends for supplemental figures S1-S6.
Figure S2 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: March 2023

miR-214 expression modulations in melanoma cells
Supplementary Table 1 from Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations
Authors: Riquelme Erick , Behrens Carmen , Lin Heather Y. , Simon George , Papadimitrakopoulou Vassiliki , Izzo Julie , Moran Cesar , Kalhor Neda , Lee J. Jack , Minna John D. , Wistuba Ignacio I.
Published: March 2023

Summary of the clinicopathological characteristics of the patients with lung adecarcinoma examined for EZH2 expression and KRAS mutations
Supplementary Figure Legend from Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations
Authors: Riquelme Erick , Behrens Carmen , Lin Heather Y. , Simon George , Papadimitrakopoulou Vassiliki , Izzo Julie , Moran Cesar , Kalhor Neda , Lee J. Jack , Minna John D. , Wistuba Ignacio I.
Published: March 2023

1.EZH2 and MEK-ERK and PI3K/AKT signaling pathway expression in lung adenocarcinoma and HBEC cell lines and 2. Sensitivity in vitro to AZD6244 and MK2206 in combination with selective EZH2 inhibitor GSK343, EPZ6438 and GSK126 in NSCLC cells.
Supplementary Figure S7 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Expression analysis of CIS genes with SB insertions in mutagenized Ba/F3 pools.
Supplementary Figure S1 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: March 2023

Flow cytometric characterization of YFP+ cells in skin of PU.1-YFPxInvEE (InvEE) and PU.1-YFPxWT (WT) mice.
Supplementary Table 4 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: March 2023

Primers for qPCR
Supplementary Table 2 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: March 2023

The differentially expressed genes (DEG) lists
Supplementary Table S3 from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: March 2023

Summary of somatic mutations in HCC tissues of each mouse type detected by whole-exome sequencing
Supplementary Figure 2 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: March 2023

Flow cytometric analysis of leukocyte infiltration in tumor tissue
Supplemental Experimental Procedures from The Beta Subunit of Hemoglobin (HBB2/HBB) Suppresses Neuroblastoma Growth and Metastasis
Authors: Maman Shelly , Sagi-Assif Orit , Yuan Weirong , Ginat Ravit , Meshel Tsipi , Zubrilov Inna , Keisari Yona , Lu Weiyue , Lu Wuyuan , Witz Isaac P.
Published: March 2023

This file includes supplemental experimental procedures. It includes a description of animals, antibodies, dialysis of lung-derived factors, in-vitro viability assays, blocking the inhibitory effect of lung-derived factors, quantitative Real-Time PCR, fixation and sectioning of frozen tissues, immunofluorescence of frozen tissue sections, protein extraction from mouse organs, western blotting, enzyme-Linked Immunosorbent assay, Isolation of primary endothelial and epithelial cells from mouse lungs, Incubation of HPF and HPEC with MicroNB cells in Transwell system, apoptosis assay, cell cycle analysis, ERK1/2, p38 and TAK1 phosphorylation, Solid-phase synthesis of human HBB segments, Conjugation of Metox peptide to FITC, Confocal microscopy for Metox cell entry, Flow cytometry for Metox cell entry, orthotopic inoculation of tumor cells, monitoring tumor growth and metastasis, RNA preparation and Reverse Transcription Polymerase Chain Reaction, quantitative real-time PCR, intravenous and intranasal treatment of Metox, hemolytic assay, and nitric oxide assay.
Supplementary Tables 1 and 2 from Aspirin Suppresses the Acquisition of Chemoresistance in Breast Cancer by Disrupting an NFκB–IL6 Signaling Axis Responsible for the Generation of Cancer Stem Cells
Authors: Saha Shilpi , Mukherjee Shravanti , Khan Poulami , Kajal Kirti , Mazumdar Minakshi , Manna Argha , Mukherjee Sanhita , De Sunanda , Jana Debarshi , Sarkar Diptendra K. , Das Tanya
Published: March 2023

Supplementary Table IA: Pathological and clinical information of the chemotherapy-treated breast cancer patients included in the study. Supplementary Table IB: Pathological and clinical information of the untreated breast cancer patients included in the study. Supplementary Table II: List of primary and secondary antibodies used in the study, Primer sets for RT-PCR, Primer sets for ChIP.
CTL CD103+ treated TGF-β on r-Ecadh-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Authors: Boutet Marie , Gauthier Ludiane , Leclerc Marine , Gros Gwendoline , de Montpreville Vincent , Théret Nathalie , Donnadieu Emmanuel , Mami-Chouaib Fathia
Published: March 2023

CTL CD103+ treated TGF-β on r-Ecadh-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Supplementary Figures S1-S8 from Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis
Authors: Xing Cheng , Lu Xing-Xing , Guo Peng-Da , Shen Tong , Zhang Shen , He Xiao-Shun , Gan Wen-Juan , Li Xiu-Ming , Wang Jing-Ru , Zhao Yuan-Yuan , Wu Hua , Li Jian-Ming
Published: March 2023

Expression of USP4 in CRC cell lines (S1); Knockdown of USP4 impairs CRC cell proliferation (S2); The degree of USP4 depletion in tumors (S3); Depletion of USP4 inhibits pulmonary metastasis in nude mice (S4); PRL-3 is indispensable for the oncogenic functions of USP4 (S5); USP4 does not affect PRL-3 mRNA expression (S6); Expression of USP4 does not Correlate with PRL-3 mRNA Levels (S7); USP4 protein levels is positively correlated with PRL-3 protein levels in xenografts (S8).
Supplementary Figure S6 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: March 2023

Supplementary Figure S6. miR-29s and catenin-ÃŽ' expression depicts an inverse correlation in 20 cases of GC tissues.
Supplementary Figure legends from Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
Authors: Pathania Rajneesh , Ramachandran Sabarish , Mariappan Gurusamy , Thakur Priyanka , Shi Huidong , Choi Jeong-Hyeon , Manicassamy Santhakumar , Kolhe Ravindra , Prasad Puttur D. , Sharma Suash , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: March 2023

Supplementary Figure legends provide clear description for the Supplementary Figures S1-S7.
Supplementary Figure S4 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: March 2023

Supplementary Figure S4. miR-29s inhibitors suppress the expression of endogenous miR-29s in GC cells.
Supplementary Figure Legends from Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
Authors: Bhola Neil E. , Jansen Valerie M. , Koch James P. , Li Hua , Formisano Luigi , Williams Janice A. , Grandis Jennifer R. , Arteaga Carlos L.
Published: March 2023

Figure Legends for Figures S1-S6
Supplementary Table S8 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: March 2023

The overlap between the up regulated genes in FANTOM5 cancer cell lines and TCGA primary tumors, and signatures of pan cancer up-regulated genes reported by Rhodes 2004 and Xu 2007.
Supplementary Figure S8 from Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-κB Signaling Pathway
Authors: Ohtsu Naoki , Nakatani Yuka , Yamashita Daisuke , Ohue Shiro , Ohnishi Takanori , Kondo Toru
Published: March 2023

Relationship between relb expression and the prognosis.
Supplementary Figure S7 from Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-κB Signaling Pathway
Authors: Ohtsu Naoki , Nakatani Yuka , Yamashita Daisuke , Ohue Shiro , Ohnishi Takanori , Kondo Toru
Published: March 2023

RelB is essential for the NSCL61 proliferation and tumorigenesis.
Supplementary materials and methods from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: March 2023

Supplementary materials and methods
Supplementary Methods from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors
Authors: Li Yong , Luo Shunqun , Ma Ruihua , Liu Jing , Xu Pingwei , Zhang Huafeng , Tang Ke , Ma Jingwei , Zhang Yi , Liang Xiaoyu , Sun Yanling , Ji Tiantian , Wang Ning , Huang Bo
Published: March 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplementary Figure S6 from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors
Authors: Li Yong , Luo Shunqun , Ma Ruihua , Liu Jing , Xu Pingwei , Zhang Huafeng , Tang Ke , Ma Jingwei , Zhang Yi , Liang Xiaoyu , Sun Yanling , Ji Tiantian , Wang Ning , Huang Bo
Published: March 2023

Supplementary Figure S6. TRCs lost PCK1 expression in conventional rigid dish and inhibition of PCK1 enzymatic activity resulted in the decrease of bulk tumor cell number.
Supplemental figures from Multinucleation and Mesenchymal-to-Epithelial Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer
Authors: Martin Sarah K. , Pu Hong , Penticuff Justin C. , Cao Zheng , Horbinski Craig , Kyprianou Natasha
Published: March 2023

Supplemental Figures 1-7. Supplemental Figure 1: This figure shows the results of the dose response of human prostate cancer lines to antiandrogen (Enzalutamide) and Docetaxel (1st line taxane chemotherapy) as single agents and in combination treatment. It also describes the effect of AR variants on prostate cancer cell migration. Supplemental Figure 2: This figures describes the findings on the combined effect of Cabazitaxel ( 2nd line taxane chemotherapy) and Enzalutamie (antiandrogen) on AR expression, cellular localization and transcriptional activity ( target gene expression) in androgen-sensitive prostate cancer cells, VCaP. Supplemental Figure 3: This figure shows the results from confocal microscopy analysis on the cellular localization of AR variants, tubulin expression and nuclear presence in Cabazitaxel-resistant prostate cancer cells. Supplemental Figure 4: This Figure indicates the effect of Cabazitaxel treatment on kinesin protein and mRNA expression in androgen-responsive prostate cancer cells VCaP. Supplemental Figure 5: This Figure shows the results from immunofluorescence for detection of centrosomal amplification (pericentrin) in CRPC 22Rv1 cells after Cabazitaxel and antiandrogen treatment. Supplemental Figure 6: This Figure schematically summarizes the therapeutic regimen/dosing for in vivo treatment of pre-clinical transgenic model of prostate cancer with Cabazitaxel and antiandrogens and the consequences of treatment on body weight. Supplementary Figure 7: This Figure schematically describes the therapeutic dosing regimen of Cabazitaxel treatment in prostate cancer human xenograft model (22Rv1 castration resistant prostate cancer) in vivo. It also provides information on the antitumor effect of treatment on tumor growth and body weight of mice.
Supplementary Data from MCPIP1 Selectively Destabilizes Transcripts Associated with an Antiapoptotic Gene Expression Program in Breast Cancer Cells That Can Elicit Complete Tumor Regression
Authors: Lu Wenbao , Ning Huan , Gu Ling , Peng Hui , Wang Qinghong , Hou Rong , Fu Mingui , Hoft Daniel F. , Liu Jianguo
Published: March 2023

Supplementary Data from MCPIP1 Selectively Destabilizes Transcripts Associated with an Antiapoptotic Gene Expression Program in Breast Cancer Cells That Can Elicit Complete Tumor Regression
Supplementary Figure Legends from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure Legends
Supplementary Figure 8 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S8. Anti-miR155 transfection induces a marked reduction of miR155 and HK2 and a contemporary increase of miR143 expression.
Supplementary Figure 5 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S5. MCF7-LTED cells are not undergoing EMT and do not activate MMPs or enhance collagen degradation.
Supplementary Figure 4 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S4. Fulvestrant (ICI 182,780) treatment impairs glucose uptake in MCF7-2A, wt-MCF7 and MCF7-LTED and increases CO2 production in wt-MCF7 and MCF7-LTED.
Supplementary Figure 1 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S1. 3-brome-pyruvate (3-BP) in combination with letrozole synergistically inhibits cancer cell growth.
Supplementary Figure Legends from ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
Authors: Metzger Todd C. , Long Hua , Potluri Shobha , Pertel Thomas , Bailey-Bucktrout Samantha L. , Lin John C. , Fu Tihui , Sharma Padmanee , Allison James P. , Feldman Reid M.R.
Published: March 2023

Supplementary Figure Legends for S1-S4
Supplemental Figure Legends from Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem–like Cells Marked by DCLK1 Kinase
Authors: Weygant Nathaniel , Ge Yang , Qu Dongfeng , Kaddis John S. , Berry William L. , May Randal , Chandrakesan Parthasarathy , Bannerman-Menson Edwin , Vega Kenneth J. , Tomasek James J. , Bronze Michael S. , An Guangyu , Houchen Courtney W.
Published: March 2023

A separate file containging supplemental figure legends as requested by the editorial office
Supplementary Table S2 from Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia
Authors: Abbasi Azhar Z. , Gordijo Claudia R. , Amini Mohammad Ali , Maeda Azusa , Rauth Andrew M. , DaCosta Ralph S. , Wu Xiao Yu
Published: March 2023

Summary of experimental design and assessments for the combination treatment with MDNPs and RT.
Supplementary Figures S1-S9 from Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia
Authors: Abbasi Azhar Z. , Gordijo Claudia R. , Amini Mohammad Ali , Maeda Azusa , Rauth Andrew M. , DaCosta Ralph S. , Wu Xiao Yu
Published: March 2023

Characterization of NPs (S1); Immunofluorescence detection and quantification of EMT6 tumor hypoxia (S2); IF detection and quantification of EMT6 tumor hypoxia (S3); Quantification of IHC images (S4); Effect of IT treatment with MDNPs alone or combined with RT on murine and human breast tumors growth (S5); Effect of IT administered MDNPs alone or in combination with RT on the growth of murine EMT6 breast tumor (S6); Effect of IV treatment with MDNPs alone or combined with RT on murine and human breast tumors growth (S7); H&E stained mammary fat pad tissues of a healthy mouse and a LMD+RT surviving mouse (S8); Effect of MDNPs treatment post irradiation (S9).
Supplemental Table 2 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

List of all verified mutations
Supplemental Figures and Tables from Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models
Authors: Li Fu , Emmerton Kim K. , Jonas Mechthild , Zhang Xinqun , Miyamoto Jamie B. , Setter Jocelyn R. , Nicholas Nicole D. , Okeley Nicole M. , Lyon Robert P. , Benjamin Dennis R. , Law Che-Leung
Published: March 2023

Supplemental figures include 1)plasma MMAE and ADC measurement. 2) Flow cytometry analysis of CD30 and CD71 of Kapars-299 and Karpas-35R cells, and in vivo ADC activity of these ADCs; and 3)CD30 FACS of Karpas299 and Karpas-35R admixed tumors. Supplemental Tables include intratumoral released drug measurement of MMAE and MMAF in post treatement admixed tumors, as well as quantification of CD30+ cells in admixed tumors consisting various implanting ratio of Karpas-299 cells
Supplemental Figure 4 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

Clonal cluster analysis. Mutations were clustered using DBSCAN based on the VAF and graphed according to timepoint. Panels A-T illustrate possible scenarios of how individual mutations may originate, evolve, and resolve based on VAF.
Table S1-5 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

Sequences of si/shRNAs and PCR primers. Information on cancer tissues. Gene sets correlated with G9a or FIH expression.
Supplementary table 8 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

Primers used for validating somatic SNVs
Figure S3-5 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

FIH hydroxylates G9a/GLP at Asn residues in ARD and inhibits G9a/GLP-mediated gene repression. This file is related to Fig. 2-3.
Supplementary table 5 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

Summary of somatic SVs
Figure S12 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

G9a/GLP mutations recorded in COSMIC database. These data are related to Fig. 6.
Supplementary Figure S5 from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
Authors: Dermawan Josephine Kam Tai , Hitomi Masahiro , Silver Daniel J. , Wu Qiulian , Sandlesh Poorva , Sloan Andrew E. , Purmal Andrei A. , Gurova Katerina V. , Rich Jeremy N. , Lathia Justin D. , Stark George R. , Venere Monica
Published: March 2023

FACT expression is not positively correlated with GSC markers in non-neoplastic brain tissues from GBM patients.
Supplementary figures from Activation of the MDA-5–IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity
Authors: Yu Xiaofei , Wang Hongxia , Li Xia , Guo Chunqing , Yuan Fang , Fisher Paul B. , Wang Xiang-Yang
Published: March 2023

This file includes supplementary data that define the tumoricidal and/or immunoregulatory activities of MDA-5 and its CARD deletion mutants using in vitro and in vivo systems.
Extended experimental procedures from Activation of the MDA-5–IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity
Authors: Yu Xiaofei , Wang Hongxia , Li Xia , Guo Chunqing , Yuan Fang , Fisher Paul B. , Wang Xiang-Yang
Published: March 2023

This file describes detailed experimental materials and methods.
Supplementary Text 2 from Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Authors: Mattina James , MacKinnon Nathalie , Henderson Valerie C. , Fergusson Dean , Kimmelman Jonathan
Published: March 2023

Double-coded extraction items. Eight extraction items prone to high interrater variability.
Supplementary Table 1 from Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Authors: Mattina James , MacKinnon Nathalie , Henderson Valerie C. , Fergusson Dean , Kimmelman Jonathan
Published: March 2023

Coding details for internal validity categories in Table 2. Adapted from our previous meta-analysis of the drug, sunitinib (5).
Supplemental Figure 1 from miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis
Authors: Tellez Carmen S. , Juri Daniel E. , Do Kieu , Picchi Maria A. , Wang Teresa , Liu Gang , Spira Avrum , Belinsky Steven A.
Published: March 2023

Analysis of miR-196b, miR-34c-5p, miR-497/195 hypermethylation in lung cancer cell lines, PBMC, and NBEC.
Supplementary Materials and Methods, Supplementary Tables 1 through 5, and Supplementary Figures 1 through 10 from Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target
Authors: Grandjean Geoffrey , de Jong Petrus R. , James Brian P. , Koh Mei Yee , Lemos Robert , Kingston John , Aleshin Alexander , Bankston Laurie A. , Miller Claudia P. , Cho Eun Jeong , Edupuganti Ramakrishna , Devkota Ashwini , Stancu Gabriel , Liddington Robert C. , Dalby Kevin N. , Powis Garth
Published: March 2023

Supplementary Materials and Methods Table S1: Data collection and refinement statistics native ALDOA and native ALDOA +TDZD8 Table S2: Data collection and refinement statistics: ALDOA-ND1 and ALDOA-ND1+TDZD-8. Table S3: Inhibition of HIF-1 activity by siRNA knockdown of glycolysis genes Table S4: Increase in glycolysis gene expression in hypoxia and the effect of siHIF-1 Table S5: Validation of screen results using alternate siRNAs Figure S1: Inhibition of HIF-1 activity and proliferation following knockdown of glycolysis genes Figure S2: Effect of knockdown of PGKs or ALDOA on HRE-luc activity on proliferation Figure S3: Effects of knockdown of ALDOA or PGK1 or PGK2 on ATP levels Figure S4: Effects of knockdown of ALDOA or PGK1 and PGK2 on HIF-1α protein levels Figure S5: Differential expression of ALDO or PGK Isoforms in tumor cells Figure S6: HIF-1 activity levels in MDA-MB-231 doxycycline inducible shALDOA clones sh8.8 and sh9.7. Figure S7: Stereo pairs of ALDOA monomer comparisons, shown as ribbon diagrams, with ligands shown as sticks Figure S8: TDZD-8 inhibition of HT-29, PANC1 and MIA PaCa-2 cancer cell proliferation, lactate formation, and HRE-luciferase reporter activity Figure S9: Effect of TDZD-8 on phospho-AMPK, phospho-p300 and ATP in PANC1 pancreatic cancer cells Figure S10: Effect of TDZD-8 treatment on levels of glycolytic intermediates and non-involved amino acids.
Table S1 from Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1
Authors: Oladimeji Peter , Skerl Rebekah , Rusch Courtney , Diakonova Maria
Published: March 2023

This file contains Supplemental Table S1 entitled " Antibodies and Inhibitors used in this study."
Supplementary Figure Legends and Methods from Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
Authors: Beyranvand Nejad Elham , van der Sluis Tetje C. , van Duikeren Suzanne , Yagita Hideo , Janssen George M. , van Veelen Peter A. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Arens Ramon
Published: March 2023

Supplementary Figure Legends and Supplementary Materials and Methods
Figure S3 from Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1
Authors: Oladimeji Peter , Skerl Rebekah , Rusch Courtney , Diakonova Maria
Published: March 2023

This file contains Supplemental Figure S3 entitled "E2-activated PAK1 forms a complex with Etk and βPIX".
Figure S2 from Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1
Authors: Oladimeji Peter , Skerl Rebekah , Rusch Courtney , Diakonova Maria
Published: March 2023

This file contains Supplemental Figure S2 entitled "Estrogen promotes formation of Gβ1γ2,5-PAK1-Etk complex".
Supplementary Figure 2 from Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
Authors: Beyranvand Nejad Elham , van der Sluis Tetje C. , van Duikeren Suzanne , Yagita Hideo , Janssen George M. , van Veelen Peter A. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Arens Ramon
Published: March 2023

Induction of tumor-specific T-cell responses are dependent on cisplatin treated tumor cells.
Supplemetary Figure S5 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

Enhanced CD8 T cell cytotoxicity to BPTF KD cells is not due to the OVA or pmel antigens.
Supplementary Figure 1 from Phytoestrogen Suppresses Efflux of the Diagnostic Marker Protoporphyrin IX in Lung Carcinoma
Authors: Fujita Hirofumi , Nagakawa Keisuke , Kobuchi Hirotsugu , Ogino Tetsuya , Kondo Yoichi , Inoue Keiji , Shuin Taro , Utsumi Toshihiko , Utsumi Kozo , Sasaki Junzo , Ohuchi Hideyo
Published: March 2023

The effects of genistein pretreatment on ALA-mediated accumulation of PpIX in various tumor cell lines.
Supplemetary Figure S1 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

BPTF does not affect 4T1 cellular morphology or proliferation in vitro.
Supplementary Figures S1-6, Supplementary Tables S1-3, Supplementary methods from TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer
Authors: Good Charly Ryan , Panjarian Shoghag , Kelly Andrew D. , Madzo Jozef , Patel Bela , Jelinek Jaroslav , Issa Jean-Pierre J.
Published: March 2023

TET1, TET2 and TET3 expression in breast cancer and its association with survival. Putative TET2 and TET3 methylation targets in breast cancer. Differential gene expression analysis in TCGA triple negative breast cancer patients. Putative TET1 methylation targets in ovarian cancer. 5hmC slot blot in TET1 KD cells. Drug validation assays. RNA-seq and DREAM analyses in Hs578T cells. CRISPR gRNA sequences. List of drugs correlated with TET1 expression in breast and ovarian cancer cell lines. Supplemental methods related to RNA-seq, DREAM and bioinformatics.
Supplementary Table 1 from SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression
Authors: Santos Juliana Carvalho , Carrasco-Garcia Estefania , Garcia-Puga Mikel , Aldaz Paula , Montes Milagrosa , Fernandez-Reyes Maria , de Oliveira Caroline Candida , Lawrie Charles H , Araúzo-Bravo Marcos J. , Ribeiro Marcelo Lima , Matheu Ander
Published: March 2023

Table with the clinical information of the patients of our cohort
Supplementary Figure S1 from Label-Free Neurosurgical Pathology with Stimulated Raman Imaging
Authors: Lu Fa-Ke , Calligaris David , Olubiyi Olutayo I. , Norton Isaiah , Yang Wenlong , Santagata Sandro , Xie X. Sunney , Golby Alexandra J. , Agar Nathalie Y.R.
Published: March 2023

The concept of registering SRS imaging with 3D MRI to guide brain tumor delineation intraoperatively.
Supplementary figure 2 from Secondary Tumors Arising in Patients Undergoing BRAF Inhibitor Therapy Exhibit Increased BRAF–CRAF Heterodimerization
Authors: Boussemart Lise , Girault Isabelle , Malka-Mahieu Hélène , Mateus Christine , Routier Emilie , Rubington Margot , Kamsu-Kom Nyam , Thomas Marina , Tomasic Gorana , Agoussi Sandrine , Breckler Marie , Laporte Mélanie , Lacroix Ludovic , Eggermont Alexander M. , Cavalcanti Andrea , Grange Florent , Adam Julien , Vagner Stéphan , Robert Caroline
Published: March 2023

Vemurafenib-induced BRAF-CRAF dimerization (2 µM, 24h) detected by in situ PLA in SK-MEL2 cell line is not decreased by the adjunction of MEK inhibitor PD0325901 (1µM, 24h): each red dot represents a BRAF-CRAF heterodimer. The cells were counterstained with DAPI (blue).
Supplementary figure 1 from Secondary Tumors Arising in Patients Undergoing BRAF Inhibitor Therapy Exhibit Increased BRAF–CRAF Heterodimerization
Authors: Boussemart Lise , Girault Isabelle , Malka-Mahieu Hélène , Mateus Christine , Routier Emilie , Rubington Margot , Kamsu-Kom Nyam , Thomas Marina , Tomasic Gorana , Agoussi Sandrine , Breckler Marie , Laporte Mélanie , Lacroix Ludovic , Eggermont Alexander M. , Cavalcanti Andrea , Grange Florent , Adam Julien , Vagner Stéphan , Robert Caroline
Published: March 2023

Proximity Ligation Assay principle. Two primary antibodies recognize the two antigens BRAF and CRAF. Specific secondary antibodies (Probes) bind to the primary antibodies and are bound to a unique short DNA. When the PLA probes are in close proximity, the DNA strands can interact. After joining they are amplified via rolling circle amplification (RCA) using a polymerase. The signal is easily made visible as a distinct brown or fluorescent dot after enzymatic conversion of a substrate.
Supplementary Figures legends from Secondary Tumors Arising in Patients Undergoing BRAF Inhibitor Therapy Exhibit Increased BRAF–CRAF Heterodimerization
Authors: Boussemart Lise , Girault Isabelle , Malka-Mahieu Hélène , Mateus Christine , Routier Emilie , Rubington Margot , Kamsu-Kom Nyam , Thomas Marina , Tomasic Gorana , Agoussi Sandrine , Breckler Marie , Laporte Mélanie , Lacroix Ludovic , Eggermont Alexander M. , Cavalcanti Andrea , Grange Florent , Adam Julien , Vagner Stéphan , Robert Caroline
Published: March 2023

Supplementary figure legends