bluuebunny/crossref_metadata_2025 huggingface dataset:
Design and Implementation of a Dynamic and Informative Housing Consultant Website
Authors: Chandrawati T. Brenda , Nugraha Johanes Arya Pramesta , Rejeki VG Sri , Anggita Lintang Jata
Published: February 2025

With the advancement of the digital revolution, the way knowledge is accessed has evolved from traditional media to more flexible and interactive digital platforms. Early websites, which were primarily static and one-directional, struggle to keep up with user expectations for dynamic and frequently updated content. This research explores the design and development of scukrsjawa3.com, an interactive educational website aimed at providing structured and engaging learning resources. Utilizing the Rapid Application Development (RAD) approach, the website was built using PHP, JavaScript, CSS, and HTML, with Bootstrap ensuring responsiveness and ease of navigation. Key features include a well-structured content system, chatbot integration, and an intuitive user interface, enhancing accessibility and engagement. This platform meets the growing demand for interactive, real-time, and user-centric learning experiences, serving as an effective tool for digital education.
BIODIVERSITY ANALYSIS OF ECTOMYCORRHIZA BASED ON SLOPE IN SORONG NATURE PARK
Authors: Ponisri Ponisri , Farida Anif
Published: February 2025

This study aims to identify and analyze the composition and distribution of ectomycorrhizal fungi in Sorong Nature Tourism Park. The method used was field observation or direct observation divided into five plots, namely in a special block of seed sources (where Agathis labelardieri trees are planted as parent trees), tourism blocks, mixed gardens, sloping area protection blocks, and steep area protection blocks. Each plot measured 100 m x 100 m with a total research area of 50,000 m2 (5 ha). The data collected were analyzed based on each parameter and presented qualitatively and quantitatively in tables and figures. The results showed the presence of 52 species of ectomycorrhizal fungi with 2,577 individuals. The most common species was Marasmiellus candidus, with 188 individuals; the least common species was Tramelia sp2, with only 10 individuals. These findings indicate that environmental factors such as light, temperature, humidity, and vegetation type significantly influence the growth and distribution of ectomycorrhizal fungi. The species diversity index was in the medium category (1.6) with a low dominance index (0.03), indicating that no fungi species dominated significantly. The high evenness index (0.93) also showed that the distribution of ectomycorrhizal fungi was relatively even in the area, reflecting the stability of the fungal community.
Down Syndrome Combined with Robertsonian Translocation (13;14) Carrier
Authors: Lestari Esa Loyallita , Utari Agustini , Winarni Tri Indah , Hendrianingtyas Meita
Published: February 2025

Down Syndrome (DS) is a genetic disorder in the form of adding chromosome 21 due to abnormal cell division. This condition causes a distinctive physical appearance and intellectual impairment. The prevalence of DS is between 10-11 out of 10,000 live births worldwide. A 2-week-old baby presented with complaints of jaundice with the clinical picture of DS. There was a mild increase in fT4 levels, and TSH levels were still within the reference value range. Karyotype examination showed Robertsonian translocation of chromosomes 13 and 14 and several abnormalities, namely trisomy 21.
Correlation High-Sensitivity Troponin-I and Length of Stay Acute Myocardial Infarction Patients Dr. Wahidin Sudirohusodo Hospital
Authors: Sari Ni Putu Yunita Puspitra , Wibawa Sulina Yanti , T. Lopa Amaliyah
Published: February 2025

Acute myocardial infarction is a part of acute coronary syndrome, which is characterized by reduced coronary blood flow causing no oxygen supply for more than 20 minutes. High-sensitivity Troponin-I test detects heart abnormalities with minimal injury to the heart muscle. The length of stay indicates the number of days a patient is hospitalized in one treatment period. This study aims to analyze the correlation between high-sensitivity Troponin-I levels and the length of stay of acute myocardial infarction patients. A retrospective analytic observational study using medical records data with a cross-sectional design. A total of 111 patients were involved in the period of January 01 to December 31, 2022. Statistical analysis using Kolmogorov-Smirnov test and Spearman's correlation test. A correlation test showed a significant correlation between high-sensitivity Troponin-I and length of stay in NSTEMI and STEMI patients with p=0.131 (p>0.05) and p=0.415 (p>0.05), respectively. This study found no significant correlation between high-sensitivity Troponin-I levels and the length of stay of acute myocardial infarction patients.
Correlation of Serum Creatinine Based on Cockcroft-Gault and CKD-EPI in Diabetes Mellitus
Authors: Hasna Hasna , Kurniawan Liong Boy , Mangarengi Fitriani
Published: February 2025

World Health Organization (WHO) predicts Indonesia's population with Type 2 Diabetes Mellitus (T2DM) will rise from 8.4 million in 2000 to 21.3 million in 2030. The primary cause of disability and death in people with Diabetes Mellitus (DM) is nephropathy. The early stages of diabetic nephropathy are characterized by glomerular hyperfiltration and an increase in the estimated-Glomerular Filtration Rate (eGFR). Other markers of diabetic nephropathy in addition to eGFR are increased creatinine, albuminuria, and proteinuria. The currently developed formulas for eGFR assessment are the Cockcroft-Gault (CG) formula, the Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI). This study aimed to determine the relationship between eGFR using the CKD-EPI formula for serum creatinine and CG in T2DM patients. Fifty-three DM patients participated in a cross-sectional study of the population of patients diagnosed with T2DM by clinicians at Hasanuddin University Hospital between March and June 2022. Version 25 of the Statistical Package for Social Science (SPSS) software was used to analyze the data. Statistical tests for the Normality of data distribution used the Kolmogorov-Smirnov test to determine the normality of data, the ANOVA test was used for comparison, and the Spearman test was used as a correlation test. The relationship between CKD-EPI and CG was highly correlated (r=0.868, p<0.001). Urine albumin levels and eGFR CKD EPI (r= -0.283, p=0.042) and CG (r= -0.282, p=0.043) showed a significant connection. There was a very strong relationship between CKD-EPI and CG.
The Difference between Coagulation Profile and Fibrinolysis in Acute and Chronic Leukemia Patients
Authors: Limijadi Edward Kurnia Setiawan , Devi Wivina Riza , Tjitradinata Cynthia
Published: February 2025

The incidence of acute and chronic leukemia has been increasing for years resulting in many complications, one of them being hypercoagulability. Evaluation can be conducted using coagulation testing, including PT, aPTT, and fibrinogen levels, as well as fibrinolysis assays, such as D-dimer levels. Studies about these parameters between acute and chronic leukemia in the first diagnosis of leukemia need to be evaluated. This study aimed to evaluate the difference in coagulation and fibrinolysis profiles between acute and chronic leukemia. This study was a cross-sectional observational analysis of 34 acute and chronic leukemia patients in Ulin Government Hospital, Banjarmasin from October 2019 to February 2020. PT, aPTT, fibrinogen level, and D-dimer were analyzed on COA Lab 1000. Independent T-test and Mann-Whitney test were used to analyze data. The test results of PT, aPTT, fibrinogen, and D-dimer levels, for acute and chronic leukemia, were 13.96±1.86 vs. 16.73±4.74 seconds (p=0.029); 39.63±2.43 vs. 45.87±13.98 seconds (p=0.154); 286,18±180,58 vs. 328,81±150,63 mg/dL (p=0.459); and 746±3.392 vs. 1,466.56±445,86 µg/L (p=0.731), respectively. Significant differences were found in Prothrombin Time (PT) between acute and chronic leukemia patients, while no notable distinctions were observed in activated Partial Thromboplastin Time (aPTT), fibrinogen levels, or D-dimer levels.
Analysis of Handgrip Strength with Insulin Resistance in Male and Female Indonesian Adults
Authors: Kurniawan Liong Boy , Sheridan Sabilla , Syafaat Andi Wali , Surur Andi Ainun Zulkiah , Nadhifah Naurah , Afandi Ichlas Nanang , Ariyandy Andi , Basri Muhammad Iqbal , Aminuddin Aminuddin
Published: February 2025

Insulin resistance, a precursor to diabetes mellitus and metabolic syndrome, has increased in prevalence in recent decades. Grip strength reflects muscle strength and is thought to provide an overview of the condition of insulin sensitivity. The purpose of this study was to evaluate the association between insulin resistance and handgrip strength in male and female Indonesian adults. This cross-sectional study recruited 169 adult participants, 71 of the subjects were males and 98 of the subjects were females. Handgrip strength, insulin, fasting glucose, HOMA-IR, and OGTT were measured, then the association between handgrip strength and insulin resistance was assessed. Linear regression analysis showed that in male subjects, relative handgrip strength was negatively associated with log HOMA-IR (univariate: B= -0.703, beta= -0.323, p=0.006; multivariate: B= -0.687, beta= -0.316, p=0.012) while no association was found in female subjects (univariate: B= -0.192, beta= -0.136, p=0.183; multivariate: B= -0.172, beta= -0.121, p=0.262). The optimal cut-off value of relative handgrip strength to assess insulin resistance is 0.45 (sensitivity 73.3%, specificity 73.1%) in the male group and 0.34 (sensitivity 68.4%, specificity 61.0%) in the female group. The weaker the handgrip strength in males, the higher the HOMA-IR value. In females, no significant correlation showed between handgrip strength and insulin resistance.
Diagnostic Value of Typhidot and TUBEX-TF in Pediatric Typhoid Fever Using Composite Reference Standard
Authors: Salipadang Eunike Jaequeline , Rauf Syarifuddin , Pelupessy Ninny Meutia , Rahimi Rahmawaty , HK Adhariana , Sarmila Besse
Published: February 2025

Typhoid fever, a systemic infection remains a significant global health concern, especially in endemic areas. Typhidot and TUBEX-TF present a quick, easy, and cost-effective, however, their diagnostic performance still needs to be evaluated. This study aims to evaluate Typhidot and TUBEX-TF diagnostic accuracy for typhoid fever in children using CRS composed of blood culture and PCR and recording its performance on fever days. This was a diagnostic study with a cross-sectional design involving children suspected of typhoid fever aged 1 to 18 years, in 7 hospitals in South Sulawesi, Indonesia from November 2023 to April 2024. Venous blood samples were collected from each respondent and tested using TUBEX-TF, Typhidot, and composite reference standard, a combination of blood culture and nested PCR, to improve diagnostic accuracy. Of 85 samples, 27 (31.8%) were positive for Typhidot, 14 (16.4%) for TUBEX-TF +4, and 44 (51.7%) for TUBEX-TF >+6. The positive rate for Typhidot dan TUBEX-TF >+6, was highest in the first week of fever (p<0.01). The sensitivity, specificity, PPV, and NPV (95% CI) of Typhidot were 43.55% (31.0-56.7), 100% (85.2-100), 100%, and 39.66%, respectively, and TUBEX-TF >+6 were 70.97% (58.1-81.8), 73.91% (51.6-89.8), 88%, and 48.57%, respectively. The combination of Typhidot and TUBEX-TF was also tested and resulted in higher diagnostic values (p=0.000). Therefore, combined Typhidot and TUBEX-TF testing is proposed as an effective strategy in the diagnosis of typhoid fever.
Analysis of Chemistry Test Topics in the Higher Education Institutions Examination Using the DEMATEL Method
Authors: Yüksel Mehmet
Published: February 2025

The aim of this study is to analyze the distribution of chemistry questions and the relationships between topics in the Higher Education Institutions Examination (YKS) Basic Proficiency Test (TYT) and Field Proficiency Test (AYT) from 2018 to 2024, based on the Secondary School Chemistry Curriculum, using the Decision-Making Trial and Evaluation Laboratory (DEMATEL) method. The research was conducted using the document analysis technique, a qualitative research method, leveraging data obtained from the database of the Measurement, Selection, and Placement Center (MSPC). Initially, the chemistry questions included in the TYT and AYT sections of the YKS between 2018 and 2024 were classified according to the topics in the Secondary School Chemistry Curriculum. The relationships between these topics were then evaluated using the DEMATEL method. Findings reveal that in the TYT chemistry section, topics such as “Atoms and the Periodic Table”, “Interactions Between Chemical Species”, and “Mixtures” appeared consistently in the exams each year, while no questions were related to the “Nature and Chemistry” unit. Regarding the topic distribution of AYT chemistry questions, it was determined that the most frequently addressed topics were “Chemistry and Electricity,” “Liquid Solutions and Solubility”, “Chemical Equilibrium”, “Organic Compounds”, and “Gases”. Conversely, no questions were asked on “Energy Resources and Scientific Developments”. When analyzing the relationships among TYT topics using DEMATEL, it was found that the topic “Chemistry Everywhere” interacted the most with other topics, while “Structure of the Atom and the Periodic Table” had the greatest influence on other topics. Similarly, when examining the relationships among AYT topics, “Chemistry and Electricity” was identified as the most interactive and influential topic. The findings of this study provide important insights for students on which topics to prioritize during their exam preparation. Additionally, this study suggests that analyses conducted using the DEMATEL method can serve as a model for evaluating curricula in other disciplines.
Coronello, il virus birbantello o il mostricciatolo con la corona. Il lessico utilizzato per descrivere COVID-19 nell’editoria per bambini può essere considerato specialistico?
Authors: Marcol-Cacoń Lucyna
Published: February 2025

L’articolo si pone lo scopo di esaminare le favole e i racconti terapeutici disponibili on-line dedicati al tema del Covid-19 e scritti in italiano intorno all’anno 2020. Lo scoppio della pandemia ha provocato uno scompaginamento della realtà nonché della normalità alla quale erano abituati i bambini. Ciò che rende le persone disarmate di fronte alla nuova realtà è soprattutto la mancanza dei vocaboli appropriati per descriverla. Racconti e favole, oltre ad essere uno strumento che dà conforto, costituiscono anche uno spazio perfetto per lo sviluppo di un lessico nuovo. L’obiettivo del presente lavoro è quello di valutare se tale lessico può essere considerato specialistico
“Anna”/“Amma” nell’Italia antica e la preistoria di Anna Perenna
Authors: Marchionni Luca
Published: February 2025

 L’articolo indaga la presenza nell’Italia antica di divinità materne il cui nome utilizza la base *an(n)a-/ *am(m)a- e cerca, sulla base di questi dati, di tracciare un confronto con Anna Perenna, mostrando la presenza di numerosi elementi comuni che possono fornire indizi sulla preistoria della divinità romana. In chiusura, inoltre, l’articolo mette a confronto i teonimi studiati con gli elementi antroponomastici dell’Italia antica risalenti alla medesima base *an(n)a-/*am(m)a-.
A Two-stage CNN Based Computer Vision Framework for Automated Validation of Indian Bank Cheques
Authors: Chakraborty Debjani , Sahoo Projjal , Biswas Argha , Maitra Sujaan , Saha Sourav , Halder Biswajit
Published: February 2025

Automated bank cheque processing is still considered a challenging task for computer vision researchers. This article proposes a two-stage deep learning-based end-to-end computer vision framework to validate an Indian bank cheque with respect to a few mistakes commonly found in manually entered handwritten fields. The proposed framework primarily works in two stages involving two separate Mask RCNN models to detect two common mistakes due to the absence of any key handwritten field or the presence of any overwritten/strike-through handwritten character in the bank cheque image. The first stage of the Mask RCNN model aims to segment all the key handwritten fields in a bank cheque image, leading to the detection of any missing handwritten field. The second stage, the Mask RCNN model, attempts to detect the presence of any overwritten/strike-through handwritten character in a bank cheque image that may lead to the invalidation of the cheque. Due to the unavailability of any standard dataset for validation purposes, a bank cheque image data repository has been prepared exclusively for developing the proposed framework. Extensive experimentation with the prepared dataset reveals that the proposed framework can outperform some of the popular frameworks by achieving a promising accuracy (98%) in terms of reporting validation errors owing to the aforementioned mistakes in the bank cheque.
Formation of Students’ Rhizomatic Thinking as an Individual Way of Processing Information and Building Their Own Text
Authors:   MGIMO University, Demina V.
Published: February 2025

In the last third of the 20th century, communication at the level of stereotypes and clip pictures, actively supported by tech­nology, resulted in forming a new type of person — ‘homo zap­ping’. The meaning is replaced by a picture, a frame, a planar image. Therefore, it is necessary to build the teaching process so as to teach students to produce their own individual text, the so-called ‘non-linear text’, internally mobile and open to interpretive pluralism, developing mature reading skills. In this regard, home reading triggers the mechanisms of the cognitive process, which consists in implementing the mechanism of ‘anticipatory reflec­tion’, ‘running ahead’ and making ‘semantic hooks’ to produce the state of ‘surprise’. In other words, students produce the rhizomatic text, which is mobile and subject to change. In this regard, such rhizomatic logic creates the basis of a new worldview and includes the real effect of the mechanism of action of the new method of managing social, technical and scientific processes.
Challenges and Solutions in Teaching Spanish as a Foreign Language in India: Exploring the Role of Mother Tongue
Authors:   Aligarh Muslim University,, Kumar Mayuresh
Published: February 2025

Teaching Spanish in India presents unique challenges. Due to its diverse geography, various teaching setups exist, catering to students’ different needs who come from diverse regions. Some have access to classrooms, while others simply cannot af­ford them. Many of them rely on outdated methods like gram­mar-translation due to a lack of awareness of modern approach­es. It is also to be noted that English proficiency is limited in rural and semi-urban areas. Teaching Spanish is challenging in this context. One solution in this case might be using the moth­er tongue, such as Hindi, to enhance understanding and to facili­tate learning. This paper explores how Spanish can be better learned through Hindi, advocating for bilingualism. The research methodology in this case is qualitative, focusing on understand­ing student motivation and beliefs while considering the broad­er implications of using mother tongue to teach a foreign lan­guage.
Palestinian Arab Students Writing Research Papers: Challenges and Remedies
Authors:   Beit Berl College, Abu Rass Ruwaida
Published: February 2025

This research investigates employing contrastive analysis (CA), text analysis (TA), error analysis (EA) and advanced technology for helping Palestinian Arab Muslim students in Israel to write their final projects, research articles (RAs). They face tremendous diffi­culties in writing their final research papers, especially providing a theoretical background because they lack adequate proficiency in English and the experience of writing research papers in their first language. In the context of this study, they should paraphrase, summarize, analyze and synthesize information from different sources, linking scholarly research to previous work in the same discipline and expressing their own voices in the text. Analyzing all of the required written assignments and the final version of their research papers shows that these students have improved their writing academic skills slightly. Results indicate the need for intensive practice to help these students acquire the necessary academic skills for writing research articles in English.
Comparison of Breast Cancer in Maranhão and Brazil From 2012 to 2022
Authors: Ipácio Alexandros Páris de Mesquita , Weba Elizabet Taylor Pimenta , Matos Eslainy Xavier , Santana Guilherme Eduardo Nolêto de Sousa , Maciel Judith Carneiro , Araújo Luca Ribeiro Santos , Alves Matheus
Published: February 2025

Objective: Compare the variables of breast cancer patients in Maranhão and Brazil between 2012 and 2022.
 
Theoretical Framework: Breast cancer is the most diagnosed neoplasm among women and, in Brazil, it is the leading cause of cancer-related deaths. A healthy lifestyle minimizes the chances of developing the disease, but does not eliminate them. Treatment varies according to the stage and type of tumor, encompassing traditional options and advancements such as genetic mapping and targeted therapies, while public policies promote early diagnosis and screening.
 
Method: Cross-sectional, retrospective, descriptive epidemiological study with a quantitative approach, based on secondary data from the Oncology Observatory, focusing on variables such as age group, type of treatment, procedures performed, mortality from breast cancer, and SUS investments by procedure groups. Data were analyzed using descriptive statistics.
 
Results and Discussion: The results revealed an increase in breast cancer incidence in Maranhão and Brazil, with rates ranging from 51.83 to 61.78 cases per 100,000 women in Brazil and from 13.35 to 23.53 in Maranhão. A higher proportion of young patients receiving outpatient treatment was observed in Maranhão, highlighting regional inequalities. Adjuvant chemotherapy was the most performed procedure, although there is underutilization of complementary services in the state. The lack of mortality data in Maranhão limits understanding of the disease's impact, emphasizing the need for monitoring strategies.
Enzymatic Potential of Bacteria Isolated From Bays of the Pantanal Mato Grosso
Authors: Lima Cristina Vitor de , Cruz Erica , Carvalho Raquel Vieira de , Chitarra Gilma Silva , Martins Meire Lelis Leal , Mariotto Sandra
Published: February 2025

Objectives: To identify bacterial strains from the Pantanal and assess their resistance to different temperatures and pH levels. To evaluate, through molecular and biochemical analyses, their potential for producing lipases, cellulases, xylanases, and proteases.
 
Theoretical Background: The Pantanal is a biome with unique characteristics, recognized for its high biodiversity, high organism density, and constant water and nutrient fluxes. Microbial enzymes are widely recognized in the industry for their high specificity and catalytic efficiency, leading to a growing demand for new enzyme-producing strains.
 
Methods: The microorganisms used in this study were collected from four bays in the Pantanal region of Mato Grosso State, two years before the major wildfires of 2020, during both the dry and wet seasons. Conventional culturing, isolations, biochemical tests, and DNA extraction were the initial steps for selecting candidates for enzymatic production assays, specifically for lipases, cellulases, xylanases, and proteases.
 
Results and Discussion: The results highlight the biotechnological potential and enzymatic capabilities of the isolated bacterial strains. Future studies should focus on optimizing substrate concentrations and nitrogen sources to enhance enzyme production from these newly identified strains.
 
Research Implications: The discovery of novel microorganisms and the screening for promising enzyme producers can contribute to industrial and technological applications. Studies employing diverse techniques have significant implications and impacts on both basic and applied research.
 
Originality/Value: Bacteria from the Pantanal in Mato Grosso remain largely unexplored. Despite this pioneering study, the sampling size is minimal considering the vast area of the biome and the diversity of ecosystems. This work aims to stimulate interest in expanding applied microbiology research, particularly in studying strains from environments undergoing constant changes.
МУЗЕЙНА ПЕДАГОГІКА В ПРОФЕСІЙНІЙ ПІДГОТОВЦІ МАЙБУТНІХ ФАХІВЦІВ У РЕСПУБЛІЦІ ПОЛЬЩІ
Authors: Білавич Галина
Published: February 2025

Стаття присвячена проблемі використання музейної педагогіки в професійній підготовці майбутніх фахівців у Республіці Польща (РП). Зазначено, що музейна освіта в закладах вищої освіти (ЗВО) РП не тільки забезпечує студентів теоретичними знаннями, а й дає їм можливість застосувати ці знання на практиці. Університети активно впроваджують музейну освіту у свої освітні програми, готуючи висококваліфікованих фахівців. Музейна освіта добре розвивається не тільки в університетах Варшави і адміністративних центрів воєводств, а й невеликих міст РП, університетські музеї стали освітніми, культурними, науковими центрами. Чимало польських університетів є важливими осередками підготовки фахівців у сфері музеології та культурної спадщини. Використання музеїв як освітнього середовища розширює можливості професійної підготовки майбутніх фахівців, формує здобувачів вищої освіти як патріотів, свідомих громадян, виховує національну пам’ять, формує національну ідентичність.
STUDENTS’ AND TEACHERS’ MENTAL HEALTH IN CROSS-CULTURAL EDUCATIONAL COMMUNICATION
Authors: Petrenko Tetyana
Published: February 2025

У статті розкрито авторське бачення підтримки ментального здоров’я студентів і викладачів під час крос-культурної комунікації. Цінним у статті є розкриття основного поняття ментального здоров’я відповідно до організації крос-культурної навчальної комунікації. Автором приділено увагу формуванню сприятливого емоційного фону навчального процесу у різних видах та каналах комунікації. Для попередження бар’єрів крос-культурної комунікації, які впливають на ментальне здоров’я студентів і викладачів, запропоновано чотири напрями використання крос-культурної навчальної комунікації для збереження і підтримки ментального здоров’я студентів і викладачів університету: 1) будувати між індивідуальні відносини учасників навчального процесу з урахуванням навчальних цілей за принципом моральної корисності, 2) супроводжувати навчальний процес позитивними ідеями філософії серця Г. Сковороди для порозуміння і забезпечення стабільно сприятливого емоційного фону навчання, 3) орієнтувати навчальну комунікацію на розвиток особистості студента не лише через результати, але й через осмислення перебігу навчальних подій, 4) забезпечувати необхідний відпочинок і попередження розумової втоми, наприклад, за допомогою частої зміни видів занять, міжпредметні зв’язки, проєкту чи групову роботу. Зазначено про доцільність вивчення потреб, мотивів навчання студентів, сфери особистого зацікавлення у результатах навчання, колективних зацікавлень у розвитку репутації університету, впливу науки освітньої компоненти на суспільство тощо. Викладач має спрямувати свою роботу на створення спільноти однодумців, залучати до співпраці і регулярного моніторингу рівня емоційного комфорту навчальної комунікації волонтерів, представників студентського самоврядування, стейголдерів, колег групи забезпечення освітньої програми, Гаранта освітньої програми. Важливим аспектом використання крос-культурної навчальної комунікації для збереження і розвитку ментального здоров’я студентів є глибоке і систематичне вивчення ресурсних можливостей відповідних дій не лише студентів, але й педагогічних працівників. Основа для ухвали рішення про способи навчальної комунікації є мета навчального заняття чи іншої форми опанування навчальної програми.
ПРОФЕСІЙНО-ПРАКТИЧНА ПІДГОТОВКА ДИЗАЙНЕРІВ: ФОРМУВАННЯ КРЕАТИВНОГО МИСЛЕННЯ ТА ВІЗУАЛЬНОЇ ГРАМОТНОСТІ ЗАСОБАМИ МУЛЬТИМЕДІЙНИХ ТЕХНОЛОГІЙ
Authors: Штайнер Тетяна , Лісогор Алла , Силенко Юлія
Published: February 2025

У статті авторами окреслено зміст поняття “професійно-практична підготовка майбутніх дизайнерів”, що передбачає кореляцію таких компонентів: опанування теоретичної бази, розвиток практичних навичок, формування творчого мислення застосування інтегрованих технологій; підготовка до командної роботи. Розглянуто шляхи інтеграції мультимедійних технологій, що виступають ефективним інструментом у розвитку креативного мислення та візуальної грамотності у майбутніх дизайнерів: 1) створення інтерактивного контенту; 2) забезпечення доступу до віртуальних платформ; 3) уможливлення використання віртуальної та доповненої реальності; 4) уможливлення організації онлайн-колаборації. Результатом дослідження авторами окреслені організаційно-методологічні умови ефективної реалізації мультимедійних технологій у професійно-практичній підготовці дизайнерів (створення сучасного технічного середовища; розробка адаптованого змісту навчальних програм, що зумовлює інтеграцію курсів з використання мультимедійних технологій; методична підтримка викладачів).
ТЕОРЕТИЧНІ ТА МЕТОДИЧНІ ОСНОВИ РОЗВИТКУ ІНШОМОВНОЇ КОМУНІКАТИВНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ ФАХІВЦІВ АГРАРНОЇ СФЕРИ
Authors: Андрєєва Марина
Published: February 2025

В Україні приділяють велику увагу якості підготовки фахівців аграрної галузі, адже сільське господарство завжди вважалося основою забезпечення продовольчої безпеки держави та добробуту її жителів. Професійна освіта студентів аграрних закладів вищої освіти включає розвиток міжкультурної діалогічної взаємодії, встановлення професійної комунікації в науковій та освітній сферах, участь у міжнародних проєктах, спрямованих на регіональні особливості виконання професійних обов’язків, що суттєво впливають на ефективність виконання професійних завдань у кожному окремому регіоні.
Розуміння та вміння користуватися професійною мовою є ключовим елементом для майбутнього агронома, адже це не лише частина іншомовної комунікативної компетентності, але й важливий інструмент для взаємодії у процесі виконання важливих професійних завдань.
Саме тому у пропонованій статті розглянуто сутність феномена комунікативної культури як важливого елемента професійної майстерності й особистісної культури спеціалістів у аграрній галузі.
Risk-Adjusted Air Traffic Management Strategies for Convective Weather Conditions
Authors: Jones James C. , Ellenbogen Zachary
Published: February 2025

Weather is a significant source of disruption and uncertainty for air traffic. This unpredictability can present significant challenges to air traffic managers when managing airport and airspace resources. The lack of data-driven decision support tools to advise stakeholders on how to best deal with weather impacts also represents a critical shortfall in enabling improved decision-making within air traffic management. In this paper, we present an epsilon-greedy approach that incorporates risk-adjusted objectives into recommendations of traffic management initiative (TMI) parameters during uncertain weather conditions. The method attempts to achieve the best performance within the context of some of the worst-case and best-case weather outcomes. The method is compared to a standard epsilon-greedy approach that attempts to maximize the expected value of an objective. The two approaches are evaluated using a parallel fast-time simulation framework over various weather scenarios. A set of TMIs at airports and airspace resources is applied and tested against seven case days in which the airspace capacity in the Northeast United States was affected by convective weather. The risk-adjusted method is generally able to achieve a higher number of operations with lower amounts of airborne holding in adverse weather conditions. The results suggest that the approach could potentially incorporate the risk preferences of air traffic stakeholders while aiding operational planning.
Exploring Representations of Muslims and Islam on Public Broadcast Television and Social Media in South Africa
Authors: Scharnick-Udemans Lee-Shae Salma , Dramat Sakeenah
Published: February 2025

Scholars from a variety of disciplines and contexts have thoroughly affirmed the systemic character of negative portrayals and limited representations of Muslims and Islam in film, television, and news media. The corpus of research on media representations of Islam and Muslims has been defined and dominated by the Global North. Scholars working in this field of inquiry acknowledge, affirm, and address the deeply discriminatory, damaging, and dangerous consequences that stereotypical, limited, inaccurate, and homogenising mediatised tropes have for the lived realities of Muslims on a global level. However, by taking on this important and urgent work, scholars have unwittingly contributed to the development of an ever-expanding oeuvre wherein the majority of scholarship on media representations of Muslims and Islam is directed towards issues of ostracism and alienation. On the contrary, the growing study of religion in digital spaces offers insight into more nuanced and diverse (self) representations and portrayals of Muslims and Islam. While digital religion studies, an outgrowth of the discipline of internet studies, is already an established and recognised sub-discipline in the field of religious studies in the Global North, the study of religion in digital spaces in Africa is a bourgeoning field of interest located within the wider tradition of religion and media scholarship. Scholars of religion in Africa have noted that while other contexts may favour an evolutionary approach to the study of religion and media generally, in African contexts media technologies and practices generally coexist. Exploratory and reflective in its orientation, this article offers a careful consideration of the historical, social, media, and political context in which Muslims in South Africa, a multi-religious, multi-racial, majority Black democratic context, are located and offers two examples that highlight how media forms and practices coexist within the location. The first set of examples, from public broadcast television, responds to the predominance of scholarship from the Global North and offers an alternative view that illustrates the ways in which the national imperatives that mandate religious diversity on public broadcast television intentionally circulate positive narratives of Muslims and Islam, yet also obscure the challenges that South African Muslims face, thereby reproducing a different kind of limited trope to that which might be encountered in the Global North. The second set of examples explores the possibilities and opportunities that social media provides for encountering and engaging more diverse, self-constructed representations of Muslims and Islam in hopes of encouraging more local scholars to take seriously the opportunities and possibilities that social media provides as sites and sources of knowledge about religion in general and Islam in particular.
A Comparison of the Islamophobic Experiences of the Female Convert and Immigrant Muslims in America
Authors: Dawoud Aliaa
Published: February 2025

This study compares the Islamophobic experiences of female converts and immigrants and their descendants in New York. It argues that Islamophobia is primarily manifested in the form of pervasive everyday racism that is levied at both female converts and immigrants alike, largely in the form of subtle nuances in their everyday interactions with non-Muslims. The study will illustrate that despite some notable differences, the experience of female converts and immigrants—and even the experience of hijabis and non-hijabis from both groups—with everyday racism is remarkably similar. This is largely because when a white American woman converts to Islam—a religion that is perceived as external to everything that America stands for—more often than not, both her whiteness and her Americanness are tarnished. Thus, she tends to be perceived as not-quite-white and not fully American anymore, which is precisely why she is subjected to most of the subtle everyday forms of Islamophobia that female immigrants experience. These include racist comments and jokes, talking to hijabis using a demeaning tone, and non-verbal nuances, such as staring at hijabis or dismissing them. The study contends that since gender issues have long played a pivotal role in the construction of otherness between Islam and the West, this seems to lead to an almost universal experience with everyday racism for Muslim women—who are identified as such through the hijab or otherwise—regardless of whether they are converts or immigrants, and irrespective of their actual or perceived racial background.
Mediated and Mediatisation of Religious Knowledge in Africa
Authors: Ndzovu Hassan
Published: February 2025

Editorial
SEARCH AND ANALYSIS OF MUTANT FORMS OF SUBTILISIN E FROM BACILLUS SUBTILIS: OPTIMIZATION OF SURFACE CHARGE-CHARGE INTERACTIONS AND THEIR EFFECT ON THE ISOELECTRIC POINT OF THE PROTEIN
Authors:   Institute for Biological Instrumentation RAS, Pushchino, Velichko A.A. , Milovidov G.D. , Shevelyova M.P. , Nemashkalov V.A.
Published: February 2025

For subtilisin E from Bacillus subtilis an in silico analysis of mutant forms, obtained by optimizing its charge-charge interactions, was carried out. The effect of these mutations on the isoelectric point was assessed. Residues Glu61 and Asp166 were replaced
by Lys, Lys71 and Lys343 by Asp. All substitutions, with the exception of Lys71Asp, increased the stability of the molecule. The
isoelectric point of a protein depended only on its total charge.
PRODUCTION OF А RABBIT WITH A KNOCKOUT OF THE CSN2 GENE (Β-CAS)
Authors:   Belgorod State National Research University, Voronina D.G. , Patrakhanov E.A. , Pokrovsky V.M. , Sushkova D.N. , Deykin A.V. , Korokin M.V.
Published: February 2025

The creation of a rabbit with a knockout of the CSN2 gene (β-cas) represents an important goal in the field of genetic technology. Its achievement will make it possible to use such animals as a background line for obtaining producers of human therapeutic
proteins, which will significantly increase the efficiency of the production of recombinant drugs. The main goal of the study was to
knock out this gene and expand biomodels of GM animals.
Stem Cell Therapy in Parkinson’s Disease: Advances in Regenerative Medicine and Clinical Applications
Authors: Kumar Devika Sanil , Ravi Roghini , Mahmood Ammar Abdul Razzak , Amirkhanyan Naslet , Polevoy Georgiy Georgiy
Published: February 2025

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the gradual loss of dopaminergic neurons in the substantia nigra, resulting in both motor and non-motor symptoms. The current treatment options, including medications and surgical procedures, primarily focus on symptom management without addressing the underlying progression of the disease. Stem cell therapy has emerged as a promising approach in regenerative medicine for PD, aiming to replace the damaged neurons, restore dopamine production, and enhance overall patient outcomes. Furthermore, the review discusses the latest developments in clinical trials, evaluating the therapeutic potential as well as the limitations of stem cell-based treatments. While preclinical studies have demonstrated encouraging results, the translation of these findings into effective clinical treatments remains a complex challenge. The diverse nature of PD, varying patient responses, and long-term safety concerns emphasize the need for ongoing research. This review provides an in-depth analysis of stem cell therapies in PD, addressing their therapeutic potential, sources, and reprogramming techniques. It critically examines key challenges such as graft purity, safety, immunological rejection, and complications like dyskinesia. By exploring advancements in neural and dental pulp stem cells, the review underlines the role of PD microenvironment in influencing outcomes and highlights cutting-edge reprogramming approaches such as episomal and polycistronic vectors and helps to gain a comprehensive understanding of current innovations, limitations, and future directions in stem cell-based treatments for PD.
Association of Dietary Protein Intake and Lean Body Mass with Severity of Metabolic Acidosis in Patients on Hemodialysis
Authors: Nair Ganga R G , Anand A , Rajappa Medha , Harinee M , Harichandrakumar KT , Priyamvada PS , Parameswaran Sreejith
Published: February 2025

Background

Persistent metabolic acidosis (MA) in hemodialysis (HD) patients leads to protein breakdown, insulin resistance, and increased cardiovascular mortality. However, there is limited literature on the prevalence, determinants, and impact of MA in HD patients in India. We studied the association between protein intake and lean body mass (LBM) with the severity of MA in patients on regular HD.

Materials and Methods

This single-center, cross-sectional study which enrolled patients >18 years on regular HD for at least 3 months. Normalized protein catabolic rate (nPCR) was measured, and protein intake was estimated using a diet diary. Urine nitrogen excretion was measured for 24 hours in patients with residual renal function, and the protein catabolic rate calculated from urea nitrogen excretion was added to the nPCR. LBM was estimated using the bioimpedance spectroscopy technique.

Results

In 107 patients, 49.53% received HD twice a week; AV fistula was the vascular access for 96%, and CKDu was the most common CKD etiology. After HD, 94 (87.85%) patients had MA, and 26 (24.29%) had uncorrected acidosis; 82.05 and 62.9% of men and women had low LBM, respectively. Protein intake in our population was 0.45 ± 0.11 g/kg/day by diet diary and 0.73 ± 0.23 g/kg from nPCR. There was no significant association between LBM and protein intake with the severity of MA.

Conclusion

Metabolic acidosis was common among HD patients but did not correlate with protein intake and LBM. Dietary protein intake was very low in HD patients.
Comparison of local inflammatory response after phacoemulsification complicated by intraoperative fluid misdirection syndrome, with draining posterior capsulorhexis
Authors:   Eye Microsurgery Ekaterinburg Center, Ekaterinburg, Russian Federation, Rebrikov I.S. , Egorova E.V. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Novosibirsk branch, Novosibirsk, Russian Federation, Demchenko N.S. ,   Eye Microsurgery Ekaterinburg Center, Ekaterinburg, Russian Federation
Published: February 2025

Purpose. To evaluate the severity of the local inflammatory response after cataract surgery complicated by intraoperative fluid misdirection syndrome (IFMS) by assessing the profile of proinflammatory cytokines in tears and morphological changes in the macular area according to OCT. To evaluate the safety and efficacy of draining posterior capsulorhexis (DPCR) in case of IFMS.

Material and methods. There were 3 groups of patients in the prospective study: control group — uneventful phacoemulsification (30 patients); comparison group — phacoemulsification complicated by IFMS with lens particles in the retrolental space (30 patients); study group — phacoemulsification complicated by IFMS with DPCR (30 patients). BCVA, the concentration of IL-6, IL-8 in tears using enzymelinked immunosorbent assay (ELISA), central retinal thickness (CRT) and the volume of the macular area according to OCT were assessed before surgery, on the 1st day, at 1 week and 1 month postop.

Results. There were no statistically significant differences between the groups in BCVA. All groups showed an increase in the CRT and macular volume at 1 week and 1 month postop. A statistically significant (p≤0.05) increase of these measurements was determined in the comparison group. In all groups, an increase in the concentration of the studied cytokines was noted on 1st day postop, followed by a decrease in the concentrations of IL-6 and IL-8 at 1 week postop. However, the degree of decrease in the concentration of proinflammatory cytokines was significantly (p≤0.05) lower in the comparison group.

Conclusion. The development of IFMS during cataract surgery leads to an increased local inflammatory response. It was confirmed by a higher concentration of proinflammatory cytokines in tears, as well as a significant increase in the CRT and volume of the macular area according to OCT at 1 month postop. Performing DPCR allows to reduce the severity of the local inflammatory response, that was confirmed by the lower concentration of pro-inflammatory cytokines in the tear compared to the comparison group with the development of IFMS, as well as the absence of significant changes in the CRT and the volume of the macular area according to OCT.

Key words: phacoemulsification, primary posterior capsulorhexis, intraoperative fluid misdirection syndrome
Phytochemical screening and Characterization using HPLC and FTIR Techniques and analysis of Antioxidant activity of Ficus Palmata (Bedu)
Authors: Singh N. , Verma R. , Aziz R.B.
Published: February 2025

From ancient times, traditional medicines have been used in Ayurveda, Siddha and Unani. Numerous illnesses are amenable to Ficus palmata treatment belonging to the Moraceae family. The goal of this work is to identify the chemical components through water, petroleum ether, acetone, ethanol and methanol extracts of Ficus palmata stems using basic phytochemical analysis, HPLC and FTIR spectroscopy. The existence of phenols, tannins, flavonoids, alkaloids, glycosides, steroids, saponins and terpenoids was demonstrated by the results of the phytochemical study. A C18-150 4.6 mm column, 10μ injection volume and 80:20 v/v (methanol: acetonitrile) mobile phase at 30°C were used to conduct a reversed-phase HPLC study.

The UV detector was used to record the detection at 210 and 290 nm. FTIR analysis of stem extracts in methanol and petroleum ether indicated the presence of aliphatic amine compounds with significant peaks along with peaks of primary amines, alcohols, amides, aldehydes, alkanes, alkyl halides, ethers, aromatics and alkenes. The assay for 1,1-diphenyl-2-pycryl-hydrazyl “DPPH” and the test for hydrogen peroxide were used to quantify the free radical scavenging activity.
Rapid detection of Salmonella species using paper based culture device
Authors: Tiwari Shveta , Shukla Varsha , Lokur Anushree
Published: February 2025

The impact of foodborne diseases (FBD) is substantial, as evidenced by 3-5 million reported infectious diarrheal cases globally, causing 1.5 billion fatalities, particularly affecting children. Salmonella, a major pathogen causing foodborne disease outbreaks, is prevalent in various food sources, including meat, poultry, seafood and dairy products. Risk factors for foodborne illnesses include unsafe food sources, inadequate cooking, improper storage, processing and packaging equipment and human factors, emphasizing the importance of Hazard Analysis Critical Control Points (HACCP) for food safety. Traditional culture-based methods for pathogen detection, while reliable, have limitations such as long detection times and the need for skilled personnel. Nucleic acid-based detection methods including amplification, hybridization, microarrays and biochips, offer high specificity, but require complex equipment and expertise.

This research focuses on developing a paper-based culture device for Salmonella detection utilizing the C8-esterase enzyme. We established a standardized method for detecting Salmonella on Portable Culture Devices (PCDs), demonstrating its efficacy by successfully identifying bacteria in artificially contaminated food samples. We determined that the ideal substrate concentration was 3 gL-1 and that the optimal temperatures for detection were 37°C and 25°C. Our device does not require the addition of an inducer or enriched cells, making it independent of these components. We accurately determined the limit of detection and time required for detection. This innovative system promises reduced labor, rapid detection, minimized reagent requirements and user-friendly operation, addressing the need for more efficient and accessible methods in food safety monitoring and outbreak prevention.