bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of clinical outcomes following percutaneous coronary intervention versus optimal medical therapy based on gray-zone fractional flow reserve in stable angina patients with intermediate coronary artery stenosis (COMFORTABLE prospective study): Study protocol for a multicenter randomized controlled trial
Authors: Kitabata Hironori , Kubo Takashi , Shiono Yasutsugu , Shimamura Kunihiro , Ino Yasushi , Tanimoto Takashi , Hayashi Yasushi , Komukai Kenichi , Sougawa Hiromichi , Kimura Keizo , Gohda Masahiro , Hashizume Toshikazu , Obana Masahiro , Maeda Kazuisa , Yamaguchi Junichi , Akasaka Takashi
Published: December 2018

Background: Even in the current drug-eluting stent era, revascularization for coronary stenosis with fractional flow reserve (FFR) between 0.75 and 0.80, the so-called “gray zone”, is a matter of debate. Previous studies have reported conflicting results regarding outcomes of revascularization vs. deferral for coronary stenosis when FFR values in the gray zone, but have had differing study designs and populations. We therefore investigate whether medical therapy plus percutaneous coronary intervention (PCI) is superior to medical therapy alone in reducing major cardiovascular events in patients presenting coronary stenosis with gray-zone FFR values.
Methods: This is a prospective, multicenter, open-label, parallel group, randomized, controlled, superiority study. A total of 410 eligible participants will be recruited and randomized to either the medical therapy plus PCI or the medical therapy alone group. The primary endpoint is one-year major adverse cardiac event (MACE), defined as a combined endpoint of all-cause death, non-fatal myocardial infarction (MI), or unplanned target vessel revascularization (TVR). Secondary endpoints include MACE at 2 and 5 years. Moreover, each individual component of the primary endpoint, cardiovascular death, target vessel-related and non-target vessel-related MI, all MI, clinically-driven TVR or non-TVR, all revascularization, stent thrombosis, and angina symptom status will be evaluated at 1, 2, and 5 years.
Discussion: This is the first prospective, multicenter, randomized, controlled study to investigate the superiority of medical therapy plus PCI over medical therapy by itself in reducing major cardiovascular events in patients presenting coronary stenosis with “gray-zone” FFR values. The results will help interventional cardiologists in making revascularization decisions regarding coronary stenosis with gray-zone FFR values.
Trial registration: University Hospital Medical Information Network Clinical Trials Registry, ID: UMIN000031526. Registered on 1 March 2018.
Key Words: Coronary physiology, fractional flow reserve, medical therapy, percutaneous coronary intervention
Effect of Volatile and Intravenous Anesthesia on Long-Term Survival of Cancer Surgery Patients: A Systematic Review and Meta-Analysis
Authors: Gong Li , Dong Chao , Cai Qian , Ouyang Wen
Published: December 2018

Background The impact of volatile anesthesia (INHA) and total intravenous anaesthesia (TIVA) on the long-term survival of patients after oncology surgery is a subject of controversy. The purpose of this study was to make overall evaluation of the association between these two anesthetic techniques and long-term prognosis of oncology patients after surgery.
Methods Databases were searched according to the PRISMA guidelines up to September 30, 2018. Hazard ratios (HRs) with its 95% confidence intervals (CIs) were calculated after multivariable analyses and propensity score (PS) adjustments. Eight retrospective cohort articles reporting data on overall survival (OS) and recurrence-free survival (RFS) were included. An inverse variance random effects meta-analysis was conducted. The Newcastle Scale was used to assess methodological quality and bias.
Results In total, about 18922 cancer patients observed were included in the meta-analysis, of which 10433 cases were available for analysis in INHA and 8489 in TIVA group. Compared to TIVA, INHA showed a shorter OS (HR =1.27, 95% CI 1.069 to 1.516, p=0.007), with a medium heterogeneity (Q-test p=0.003, I-squared=67.6%). However, no significant differences were identified between INHA and TIVA group (HR =1.10, 95% CI 0.729 to 1.659, p=0.651) concerning RFS albeit from a limited data pool. When a subgroup analysis was performed by race, the association was more likely to be observed in the Asian studies (HR=1.46, 95%CI 1.19–1.8, p =0.00), with a much lower heterogeneity (Q-test p=0.148, I-squared=44%). When comparison was done only in breast cancer patients, no significant differences were found for OS (HR=1.625, 95%CI 0.273-9.67, p=0.594) between INHA and TIVA.
Conclusion TIVA for cancer surgery might be associated with better OS compared to INHA. The effect of INHA and TIVA on OS and RFS in the perioperative setting remains uncertain, cancer-specific, and has low-level evidence at present. Randomized controlled trials are required in future work.
Visual Field Characteristics of Normal Subjects using the Peripheral 60-4 Test for Stimulus Sizes III, V, and VI
Authors: Wall Michael , Marín-Franch Iván , Haas Jordan , Johnson Chris A
Published: December 2018

Purpose: To investigate whether the visual field characteristics, which are well known for Goldmann stimulus size III in the central 30°, hold true for the 30°–60° visual field for stimulus sizes III, V and VI.
Methods: One eye of 60 healthy participants ages 19–78 years, mean age 49.5 ± 18.0 were tested with stimulus sizes III, V and VI on two separate visits with the Humphrey 60–4 program. Pointwise between-subject variability of the average visual field of the two visits was estimated after correcting for age effects as the standard deviation across subjects. Within-subject variability was estimated as the standard deviation of the differences between visits.
Results: For the 60–4 testing, the age-corrected mean sensitivity over all test locations was smallest for size III at 22 dB. It was 7 dB greater for size V and 9 dB greater for size VI. Sensitivities decreased by about 0.38, 0.34 and 0.31 dB / degree eccentricity with sizes III, V, and VI, respectively. The differences in mean sensitivity and in eccentricity effects were statistically significant among sizes (p < 0.001). Pointwise between- and within-subject variability was greatest in the nasal and superior visual field and inversely proportional to stimulus size.
Conclusions: Visual field sensitivity was lower for smaller stimulus sizes and decreased with eccentricity and age. The between- and within-subject variability decreased with increasing stimulus size. These findings provide a basis for quantitative assessment of 60-4 visual field properties in patients with ocular and neurologic disorders.
Keywords: Perimetry, Visual Field, Vision Testing
Peculiarities of social workers’ and social pedagogues’ psychological empowerment in the aspects of self-determination theory and demographic variables
Authors: Kepalaitė Albina , Vaitkevičienė Asta , Drungėlaitė Eglė
Published: December 2018

Social workers’ and social pedagogues’ sense of power is very important for providing social assistance and support to clients and learners. Sense of power depends on meeting the needs of autonomy, competence and relatedness. Failure to meet these needs due to lack of reward, punishments or cultural rituals causes reduces or completely restricts the subjective experience of power, increasing defensiveness and psychopathology. Social workers and social pedagogues provide social assistance and support to their clients and learners based on the empowerment strategy. It is therefore important to investigate whether the very social workers and social pedagogues feel empowered. This study aims to disclose social workers’ and social pedagogues’ psychological empowerment peculiarities with regard to demographic characteristics, gender, profession, qualification category and the occupied share of the post.
Social innovation concept and implementation in the European Union and in the Republic of Lithuania
Authors: Žičkienė Skaidrė , Tamošiūnas Teodoras
Published: December 2018

The aim of the paper is to disclose the importance of social innovation and generalize innovation promotion policy in the European Union, assessing the actual situation in Lithuania. The need for social innovation is inevitable as different social problems touch modern society. Business, governments, non-governmental organizations have distinct roles and encourage social innovation in different ways, but political will and financial possibilities can lead to great changes. The policy of promoting innovation in Lithuania is in line with the provisions of EU documents, however, in the general innovation system context, little attention is paid to social innovation. Following the evaluation of Lithuania’s performance of the research and innovation system, it has been determined that the indicators which were evaluated as weaknesses are primarily related to social problems.
Lasing in optically induced gap states in photonic graphene
Authors: Milićević Marijana , Bleu Olivier , Solnyshkov Dmitry , Sagnes Isabelle , Lemaître Aristide , Le Gratiet Luc , Harouri Abdelmounaim , Bloch Jacqueline , Malpuech Guillaume , Amo Alberto
Published: December 2018

We report polariton lasing in localised gap states in a honeycomb
lattice of coupled micropillars. Localisation of the modes is induced by
the optical potential created by the excitation beam, requiring no
additional engineering of the otherwise homogeneous polariton lattice.
The spatial shape of the gap states arises from the interplay of the
orbital angular momentum eigenmodes of the cylindrical potential created
by the excitation beam and the hexagonal symmetry of the underlying
lattice. Our results provide insights into the engineering of defect
states in two-dimensional lattices.
Estudio de plantas medicinales desde conocimientos shipibo. Masisea, Perú
Authors: Cauper Samuel
Published: December 2018

En el presente estudio se reportan los conocimientos ancestrales indígenas (etnoconocimientos) de la comunidad indígena Shipibo de Preferida, Caimito y San Rafael. Las comunidades están ubicadas en el distrito de Masisea, provincia de Coronel Portillo, Región Ucayali, Perú. La recolección de datos se realizó a través de talleres participativos, entrevistas y recorridos en la concesión de la Universidad Alas Peruanas y terrenos de chacras de las comunidades shipibo para realizar la recolectar de especies vegetales in situ, acompañados por el informante etnobotánica Shipibo y los pobladores con experiencias y conocimientos de plantas medicinales en sus territorios.
Prevalencia de patologías ginecológicas infanto-juvenil
Authors: Crespo Delia
Published: December 2018

La prevalencia de enfermedades ginecológicas en las edades infantiles suele aparecer pocas veces en las niñas, no así, en la adolescencia, dependiendo si es temprana, media o tardía, el objetivo de la investigación fue determinar la prevalencia de patologías en estos grupos etarios en la ciudad de Guayaquil-Ecuador en el periodo comprendido entre enero de 2015 a enero de 2018.
Participación activa y valoración de los materiales didácticos en el éxito/fracaso académico en Educación a Distancia (Active participation and evaluation of the didactic materials in success / failure academic in Distance Education)
Authors: García Flores Segundo Agustín
Published: December 2018

La formación profesional de calidad en el nivel de educación a distancia requiere tener un reporte de la inﬂuencia de la Participación Activa y la Valoración de los materiales didácticos en el éxito/fracaso académico de los estudiantes de la Universidad Alas Peruanas. Por ello, el objetivo fue analizar dicha inﬂuencia en las califcaciones fnales de asignatura, siendo la Hipótesis que dichas variables inﬂuyen positivamente en el éxito/fracaso académico. La investigación es de tipo básica, de nivel correlacional. El diseño es no experimental, transversal. El método es hipotético-deductivo. La muestra estuvo compuesta por 153 estudiantes del semestre 2016-II. El modelo logístico aplicado en el contraste de hipótesis tiene una capacidad de clasifcar correctamente al 68,6% de los casos analizados. Valor de corte 0,5. La prueba de Hosmer y Lemeshow para el modelo tiene chicuadrado = 0,159, gl = 1 y p-valor de 0,690. Para α = 0,05, se evidencia que el modelo tiene un buen ajuste de datos. Los resultados obtenidos corroboran una inﬂuencia signifcativa en las califcaciones fnales de asignatura por parte de las variables participación activa, con IC para Exp(B) de 1,460 a 32,962; así como de la valoración positiva del material digital disponible en la plataforma Blackboard y los materiales impresos recibidos, con IC para Exp(B) de 1,772 a 82,55.
Visualización de indicadores de actividad docente en educación en línea como apoyo a la evaluación formativa
Authors: Miranda Díaz Germán Alejandro , Delgado Celis Zaira Yael
Published: December 2018

La educación en línea ha tenido un auge significativo y cobra especial relevancia la evaluación de los aprendizajes, del sistema y de la actividad docente para valorar su éxito. Este último ha sido evaluado en la literatura a partir de indicadores de actividad docente que provienen de la modalidad presencial lo cual restringe su alcance. Por ello, se requiere de indicadores de actividad docente que respondan a las características de la modalidad, que aprovechen los datos almacenados en las bases de datos de los entornos digitales utilizados y, simultáneamente que estos puedan ser presentados a los docentes de forma comprensiva para contribuir a su formación respecto a su ejecución. Así, el presente trabajo tiene como objetivo determinar el uso de la visualización de indicadores formativos describiendo dos indicadores, tiempo estimado de trabajo plataforma e interacción dialógica en plataforma docente-alumno. Se analizaron los datos de la actividad de 146 docentes y 3,556 alumnos en un periodo de 18 semanas con 18,592,774 registros en plataforma.
La importancia del reconocimiento legal de la consulta previa a comunidades campesinas en el Perú
Authors: Guerrero Carranza Gilberto Vladimir , Vásquez Sánchez José Ronald
Published: December 2018

El artículo 1 del Convenio 169 de la OIT (Organización Internacional del Trabajo, 1989) institucionaliza el derecho de consulta previa enfocado en garantizar a los pueblos indígenas que tengan una participación más interviniente cada vez que el Estado tome decisiones de carácter político, social y económico en los procesos que puedan afectar el entorno cultural de las mismas. La ley N° 29785 (Congreso de la República, 2011) promulgada el 6 de septiembre de 2011 regula el derecho a la consulta previa de los pueblos indígenas u originarios del país, la misma que no regula a las comunidades campesinas como sujetos de la presente norma. Esto es, en principio una acción muy reprochable debido a que actualmente se viene realizando actividades de exploración y explotación en territorio campesino sin tener en cuenta la afectación al derecho constitucional avivir y desarrollarse en un ambiente sano y equilibrado para el desarrollo de la vida. La propuesta planteada es que el derecho a la consulta previa debe aplicarse tanto a comunidades nativas como a las comunidades campesinas, porque la mera realización de una actividad minera afecta derechos  fundamentales y el entorno cultural, con la finalidad de prevenir posibles conflictos sociales.
El Tribunal Constitucional y el rol del juez constitucional
Authors: Miranda Canales Manuel
Published: December 2018

El presente artículo tiene como objetivo introducir algunas ideas sobre la naturaleza del Tribunal Constitucional en general, y del rol del juez constitucional en particular. En ese sentido, se resalta la labor del Tribunal Constitucional peruano como garante de los derechos fundamentales y la separación de poderes dentro de todo Estado constitucional que se precie de serlo.
Decisiones judiciales referidas al comercio electrónico en la Argentina desde el derecho de consumidores y usuarios
Authors: Tambussi Carlos Eduardo
Published: December 2018

El presente trabajo reseña los principales fallos de los tribunales argentinos, dictados contemporáneamente con la vigencia del Código Civil y Comercial de la Nación, y aun anteriores, donde se incorporan las primeras normas nacionales regulatorias del comercio electrónico en el marco de los contratos de consumo y especialmente dirigidas a los derechos de los consumidores en lo que respecta a la responsabilidad por daños de los llamados “portales de venta”, la jurisdicciónaplicable, el ejercicio del derecho de arrepentimiento y las interpretaciones desde el derecho administrativo sancionatorio. En esos aspectos se aprecia una tendencia con algunos retrocesos al avance en la protección del consumidor, a la par que se aprecia con mayor claridad la necesidad de mayor precisión regulatoria y normativa específica, para continuar en el camino de regulaciónde esta manera cada vez más generalizada de realizar actos de consumo, y para muchos bienes y servicios, la única posibilidad.
La nulidad del acto administrativo en la legislación administrativa general
Authors: Ponce Rivera Carlos Alexander , Muñoz Ccuro Felipa Elvira
Published: December 2018

El procedimiento administrativo es un conjunto de trámites que tienen por finalidad lograr que la Administración pueda cumplir con su función reguladora a través de una declaración que debe estar revestida de un conjunto de elementos que garantizan que cumpla con su finalidad. Sin embargo, siempre existe la posibilidad de que la declaración emitida sea errada, obligando a la Administración a actuar para eliminarla del ordenamiento jurídico y con ella todos sus efectos, lo cual no es automático, sino que requiere de la existencia de alguna de las causales expresamente establecidas en la ley y además de la demostración de que el acto que se pretende anular agravia al interés público, algo que no siempre es fácil de alegar o demostrar. Asimismo, la declaraciónde nulidad está precedida de un análisis en donde concurre el administrado mismo al hacer uso de su derecho de defensa. El presente artículo aborda desde una perspectiva doctrinaria algunos de los aspectos más importantes de una de las instituciones más importantes del derecho administrativo, partiendo de la conceptualización del acto administrativo, definiendo el concepto de nulidad y diferenciándolo de la anulabilidad, pero bajo una perspectiva guiada por los principios que regulan el derecho público, desarrollando las causales para su declaración de las formas que la legislación reconoce para ello.
Canon y regalías mineras: situación actual y propuesta de políticas para su aplicación eficiente
Authors: Medrano Sánchez María Isabel , Obeso Cuadra Jessica Karina , Morón Paredes Geraldo , Masías Vidal José Luis , Moreano Márquez Wendy Lidia , García Segovia María Eugenia , Coveñas Lalupu José
Published: December 2018

El Perú es un país que goza de una larga tradición minera en América Latina y el mundo. Se le conoce por ser el segundo productor de cobre, plata y zinc a nivel mundial. En América Latina, ocupa el primer lugar en la producción de oro, zinc y plomo. Posee las mayores reservas de plata del mundo y se ubica en tercer lugar en reservas de cobre a nivel mundial, mientras que en Latinoamérica lidera el ranking en reservas de plomo, zinc y molibdeno. Ello refleja el enormepotencial mineralógico que alberga. Es un país bendecido con la existencia de estos recursos naturales y la potestad de su aprovechamiento recae en el Estado, pues fija las condiciones para su aprovechamiento, el mismo que tiene que ser sostenible, y la generación de riquezas proveniente de ese aprovechamiento debe ser repartido de una manera justa y equilibrada a toda la Nación. Sin embargo, nuestro modelo de distribución del canon minero previsto constitucionalmente en el artículo 77, con el reconocimiento del derecho que le asiste a los Gobiernos locales y regionales para recibir una porción de lo recaudado en beneficio de su comunidad, calculado sobre la base de la totalidad de ingresos y rentas provenientes de la explotación de recursos naturales desus circunscripciones, presenta serias deficiencias, advirtiéndose desigualdad social, corrupción y conflictos sociales. El Congreso de la República aprobó en 2018 la utilización de los recursos del canon para el financiamiento de proyectos de vivienda social; sin embargo, consideramos que si bien es cierto representa avance en la utilización del canon, existen problemas graves que requierende otras medidas; por ejemplo, vemos un pueblo rico conviviendo al costado de otro pobre en cuyas áreas se realiza actividad minera, visualizando una inequidad en la distribución y utilización del canon minero. ¿Qué hacer? Contestando la interrogante, planteamos la implementación depolíticas para la repartición y manejo del canon minero mediante cinco recomendaciones que presentamos al final de este artículo, para su utilización eficiente. No proponemos el ejercicio irrestricto de las prácticas fiscales sino mejoras en su reasignación, división y utilización con la finalidad de mermar la inequidad y desigualdad de los pueblos.
Human resource development in Arab writing
Authors: Ensour Waed
Published: December 2018

This study is a systematic review of the existing Arab literature on human resource development (HRD). A review of Arab HRD’s theoretical and empirical articles during the period 1964–2016 in peer-reviewed journals was conducted. Content analysis was utilized to examine how HRD is conceptualized, what purposes are attached to HRD and what activities HRD encompasses in Arab literature.It was found that the basic construct of HRD is employee development, targeted toward “individuals” and encompassing training, education and learning. Arab HRD has a strong performance orientation, and tends to emphasize utilitarian outlooks, as the role of HRD is perceived to be “instrumental” and “outcome focused”. HRD in Arab literature falls under the traditional functionalist school within the managerialist perspective and is essentially based on the principles of human capital theory. The issues of social justice, power, diversity and equity are rare in Arab HRD literature. Although the Arab view of HRD has been influenced by the American school, it is still in an early stage of growth, lacks a clear disposition and is still confined within the stance of traditional training.
Congenital skin papilloma in a foal – a case of a surgical CO2 laser treatment
Authors: N. SIWIŃSKA , A. ŻAK , M. SŁOWIKOWSKA , A. NIEDŹWIEDŹ , G. SAPIKOWSKI , R. CIAPUTA , M. NOWAK , J. POPIEL
Published: December 2018

Skin papilloma in humans and animals is a relatively common dermatological problem. The most common form of these changes are acquired papillomas, and while congenital ones are rare, they were most often described in humans and horses. The present article describes the first case in Poland of congenital single skin papilloma in a newborn thoroughbred foal, surgically removed using a CO2 laser. The treatment was carried out after 3 months from birth when the change began to progress. Removal was performed on the standing animal with pharmacological sedation. Histopathological examination confirmed the diagnosis. The convalescence process proceeded without complications, with quick healing and no scar remaining.
Haemangiopericytomas in dogs: Epidemiological analysis of 136 cases
Authors: SAPIERZYŃSKI RAFAŁ , CZOPOWICZ MICHAŁ , STOPKA DIANA
Published: December 2018

Perivascular wall tumors (PWTs or haemangiopericytomas) are common in dogs, and they are clinically important in veterinary oncology, but there is no data on the occurrence of these tumors in dogs in Poland. The aim of the present study was an epidemiological analysis of canine perivascular wall tumors. The study included 136 dogs with recognized PWTs (whose frequency of occurrence was the same in females and males). The mean age of the dogs was 9.8±3.0 years, with no statistically significant difference between sexes. Among the dogs, 40.7% were mongrels, and 59.3% were purebred. Among the purebred dogs, 21 (26.3%) were German Shepherds, 17 (21.3%) were Boxers, 5 (6.3%) were Doberman pinchers and Rottweilers. Statistical analysis revealed that four breeds were predisposed to perivascular wall tumors in comparison to the general dog population: German Shepherds, Boxers, Doberman pinchers and Rottweilers. Moreover, large-breed (but not giant-breed) dogs were shown to be predisposed to PWTs. Tumors were located in the skin or subcutis of the entire body, mostly on the legs, more seldom on the trunk or the head. The most typical location for PWTs was the elbow area (11% of all cases).
SOCIOLOGY OF FOOD: «ETERNAL» PROBLEM BETWEEN TRADITION AND TRANSITIVITY. Book Review: Kravchenko S. A., Zarubina N. N., Noskova A. V., Karpova D. N., Goloukhova D. V. Sociology of Nutrition: Traditions and Transformations. Moscow: MGIMO-University, 2017. 302 p.
Authors: Головацкий Евгений , Golovatsky Eugene
Published: December 2018

The collective monograph «Sociology of Nutrition: Traditions and Transformations» is reviewed under the general editorship of N. N. Zarubina and S. A. Kravchenko. The work raises relevant and socially significant problems and prospects for the development of an interesting sociological trend – the sociology of nutrition. In the system of the consumer society, food industry has recently undergone significant transformations associated with risks, vulnerabilities, and new public expectations. The authors of the collective monograph cover a specific sphere of social relations as a cohesive whole, considering a bunch of traditional and alternative social nutrition practices, taking into account the Russian specifics. The monograph notes the resource nature of the «food addiction» of modern society in the socio-economic, political (global), as well as informational and communicative aspects of the development of modern society. Nutrition, being an integral part of the system of social relations, is subject to modern challenges and vulnerabilities of our world. Finally, the authors offer some perspective «menu» for the development of nutrition practices in modern Russia.
TOLERANCE: IS THERE AN ALTERNATIVE?
Authors: Кулемзин Анаталий , Kulemzin Anatoliy
Published: December 2018

The article suggests a re-evaluation of theoretical and practical application of tolerance in its contemporary European-American understanding as a concealed expansion of spiritual values, extraneous to Russian mentality. One of the conduits of this tolerance, propagating “western values” and alien to Russian peoples, is satirical comedy shows on Russian television, where a Russian person is depicted as a primitive brute. We examine the history of various understanding of cultural values between Russian people and western countries. Fundamental traditional moral and ethical values and cultural experience of Russian peoples are considered to be top priority in cultural development. For this reason, the author suggests establishing learning and teaching and academic centres and departments to study, preserve and actualize traditional cultures of native peoples of Siberia, the Far North and the Far East, as well as to research and regenerate Russian traditional culture.
AN INTEGRATED APPROACH TO LABOUR MARKET SITUATION ASSESSMENT
Authors: Миляева Лариса , Milyaeva Larisa
Published: December 2018

The current paper highlights the social and economic importance of adequate diagnostics of labor market situation acting as the tension/well-being indicator in society. It lists the shortcomings of the currently available mono-approaches, which are mostly limited to either a statistic analysis or a typological analysis the unemployed registered by state and/or private employment services. The study offers an original technique of complex social and statistical assessment of the situation in labor market whose information base is formed by two types of sources: reports and statistical information from job centers and materials provided by selective sociological surveys among the unemployed. The key indicator of the technique in question is the level of the labor market situation, with the hypothetical range varying from 0.20 to 1.00. It allows one to diagnose five types of situations: ideal, safe, normal, problematic and critical. The research offers a card of expert estimates of the parameters characterizing a situation in local labor market. The paper provides a step-by-step algorithm of the technique illustrated by a tentative example. The author puts special stress on the innovative character of the method and proves the need to replicate the technique in profile editions. Keywords: local labor market, social and statistical assessment, integrated approach, methodical tools.
THE ROLE OF NONPROFIT ORGANIZATIONS IN IMPROVING THE QUALITY OF LIFE OF THE POPULATION
Authors: Минаева Татьяна , Minaeva Tatyana
Published: December 2018

The second decade of the XXI century has seen major changes concerning the activities of non-profit organizations. First, the status of non-profit organizations (NPOs) as a subject of social policy has significantly improved, aided by some changes in the socioeconomic structure of various states after the global crisis. This trend is characteristic of most developed countries in the world. Secondly, the NPOs have become more popular among the population: as a result, both the number of NPO members and their professionalism have increased. Thirdly, government agencies are responding to modern challenges and become actively engaged in the development and implementation of mechanisms supporting and enabling socially oriented NPOs. All these factors show that the activity of non-profit organizations is becoming an integral part of socio-economic processes that improve the quality of life of the population. A list of public utility services provided by NPOs covers the main range of indicators of quality of life of the population. About 60 percent of the more than 223 thousand NPOs registered in the country have received the status of socially oriented nonprofit organizations (SONPOs), which allows them to rely on state support. To further enhance the effectiveness of socially oriented non-profit organizations one should: improve the regulatory framework, including preferential loans and banking services for socially oriented NGOs; develop the supportive infrastructure for socially oriented NPOs; share experience, e.g. through the establishment of advisory centers and implementation of mentoring in the field SONPOs; include SONPOs in assessing the effectiveness of the authorities in the field of social policy; inform citizens about the possibilities to receive services from the SONPOs and their activities in general.
Relationship Between Land Use and Water Quality in a Subtropical River Basin
Authors: De-Carli Bruno Paes , Souza José Carlos de , Sousa Jocy Ana Paixão de , Shoegima Thiago Franco , Barreiro Maria Del Pilar Romero , Dutra Ana Carolina , Medeiros Gerson Araújo de , Ribeiro Admilson Írio , Bressane Adriano
Published: December 2018

This study investigated the influence of land use on water quality parameters in the subtropical basin of Jundiaí-Mirim river. Water samples were collected to measure nutrients concentration and direct measurements by multiparameter probe were performed, as well as landscape analysis, using satellite images and visits in the sampling sites, besides analysis of population density data. Data were standardized and the correlation between the variables was measured using Spearman approach. Land use in the surrounding area of the sampling points had strong and significant correlations (p < 0.05) with some of the water quality parameters evaluated. These correlations had different causes, explained by the land use in a 50 m radius, or 500 m radius, or even beyond these environments studied. Landscape analysis has proved to be an important tool for understanding the interaction between water quality and land use.
Enhancing State Standardization of the Retail Trade System in Russia
Authors: Karashchuk O. S.
Published: December 2018

The goal of the article is to ground proposals dealing with enhancement of state standardization of the retail trade system in Russia. In some Russian regions there is a poor provision of the population with retail trade enterprises, which requires certain steps aimed at developing the trade system on the part of state. State regulation of the trade system in Russia is carried out by standards of minimum provision of the population with the area of trade facilities, which are fixed by bodies of power of Russian Federation entities and bodies of local self-governance and approved by the government. However, only 3% of municipal establishments in the country have developed these standards, which demonstrate the low practical importance of figures being adopted. The author puts forward a hypothesis, according to which figures of the trade area per thousand of dwellers used as a standard of min provision of the population with retail trade in Russia should be revised due to market development of trade in this country. To check the hypothesis the author studied works by prominent scientists dealing with this subject and found out that in countries with the developed market system the indicator of the population rekoning on the number of enterprises is taken as a standard. The effective methodology of figures standardization in Russia was researched and it showed its poor scientific validity. As a result, it was proposed to change the standard of min provision of the population with the retail trade and use the standard of the number of trade units per one dweller differentiated by forms of trade. Recommendations of the article form a sound basis for enhancement of the effective standard-legal regulation of the trade system in Russia.
Concerning Sustainable Development of Economic Systems
Authors: Orlova L. N. , Kuznetsov V. V.
Published: December 2018

The current technological development provides a foundation for fast growth of well-being in industrialized countries and at the same time causes global economic misbalance. Growing production and consumption lead to wasteful use of resources and increasing contamination of air, water and soil. In order to meet basic needs we cause damage to the environment. The article investigates the issues of strategic survival of society in conditions of natural resources deficit. The concept of sustainable development adopted and accepted in the whole world is, unfortunately just a concept in many spheres and it requires development and introduction of economic mechanisms of rational use of resources of all types. The continuously increasing speed of changes has become a principle factor of economic growth. But the economic approach is a pivot of the concept of sustainable development. The authors proved that only observance of balance between economic, social and ecological interests of business entities and their harmonization at the expense of innovation, which were used in economic, social and ecological life of society, could result in sustainable development of economic systems.
Marketing Research of the Medical Institution in the System of Voluntary Medical Insurance for Making Managerial Decisions
Authors: Tsvetkova A. B. , Yunisov R. Kh.
Published: December 2018

The segment of voluntary medical insurance is a promising type of insurance. This situation encourages insurers to develop advanced competitive products with continuously upgrading level of service. It is very important to pay special attention to legal and medical and economic protection of the ensured. It is clear that the insurance company needs data of marketing research for its efficient work. However, we should bear in mind that one party of the voluntary medical insurance is a medical institution, which is involved in the process and understands the importance of marketing information system data while signing the contract with the insurance company. Systematized data of the medical institution gives an opportunity to choose an optimal partner. The article using the example of NMHC named after N.I.Pirogov shows which data is analyzed by the medical institution and why and demonstrates how the mechanism of making decision about choosing the insurance company looks like. It was highlighted that using the internal information could allow the medical institution to save money and time necessary to process data and make the final decision. The authors ground recommendations for using the research in the process of signing the contract with the insurance company, a relevant model was built as an illustration.
Overseas Experience of Introducing Advanced Technologies of Production System Upgrading
Authors: Baurina S. B. , Akulenko N. B.
Published: December 2018

Today's enterprise in order to be competitive needs not only to use high technologies, put out science-intensive products and have the R & D department with high innovation potential. To response in good time and adequately to challenges called 'digital economy' the company will be able only if it possesses a flexible adaptive production system providing synergy to all divisions, all employees of the enterprise. This system should continuously upgrade not to lose its relevance. The article deals with methodology of '20 keys' as an integrator of well-known approaches to enhancing the organization work. Its specific features and advantages were identified, as well as concrete results of introducing this methodology by overseas companies, in particular, the American company 'Windfall Products' specializing in production of powder metal components. The system of five-level appraisal of the organization formulated in the company is introduced in the article. Key stages of reforming conducted in the company, concrete processes and steps being in line with each of the stages are described there. Benefits of the program of '20 keys' for realizing modern tools and approaches to business enhancement are also included in the article.
GC-MS Characterization of Phyto-Components in the Ethanolic and Hydroalcoholic Extracts of Cocos nucifera Endocarp and Evaluation of their Antimalarial Potential
Authors: Aggarwal Babita , Sharma Pankaj , Lamba Hardarshan Singh
Published: December 2018

Background:

Plants are rich and cheap source of active phytoconstituents. Present study
was performed in order to authenticate the traditional use of Cocos nucifera in malaria treatment as
well as to search an alternative for drug resistant parasites.

Objective:

In the present investigation, ethanolic (ACN) and hydroalcoholic (HACN) extracts of Cocos
nucifera endocarp were evaluated for antimalarial potential as well as subjected to GC-MS
analysis to characterize the bioactive components.

Methods:

In vitro antiplasmodial activity of ACN and HACN was assessed against P. falciparum
strains MRC-02 (CQ sensitive) and RKL-09 (CQ resistant) and percentage schizont maturation inhibition
was determined. To confirm the antimalarial potential, in vivo Peter’s 4-Day suppressive test
using P. berghei strain was performed at a dose of 25 and 50 mg/kg/day for 4 consecutive days. Bioactive
components were characterized by the application of Gas chromatography and Mass spectrometric
technique to the extracts.

Results:

Promising in vitro antiplasmodial activity was exhibited by both alcoholic (ACN) and hydroalcoholic
(HACN) extracts against P. falciparum strains MRC-02 (CQ sensitive) with IC50 values
< 5 µg/mL. HACN (% Suppression = 75.43 ± 0.18; MST=19.21 days) and ACN (% Suppression =
34.65 ± 0.11; MST=10.11 days) showed moderate in vivo antimalarial activity (p < 0.05) at dose 50
mg/Kg while standard drug chloroquine (8mg/kg) suppressed 100% parasitaemia. Twenty compounds
have been identified and characterized by GC-MS studies.
Research on Optimal CDMA Multiuser Detection Based on Stochastic Hopfield Neural Network
Authors: Fan Tongke
Published: December 2018

Background:

Most of the common multi-user detection techniques have the shortcomings
of large computation and slow operation. For Hopfield neural networks, there are some problems
such as high-speed searching ability and parallel processing, but there are local convergence problems.

Objective:

The stochastic Hopfield neural network avoids local convergence by introducing noise
into the state variables and then achieves the optimal detection.

Methods:

Based on the study of CDMA communication model, this paper presents and models the
problem of multi-user detection. Then a new stochastic Hopfield neural network is obtained by introducing
a stochastic disturbance into the traditional Hopfield neural network. Finally, the problem
of CDMA multi-user detection is simulated.

Conclusion:

The results show that the introduction of stochastic disturbance into Hopfield neural
network can help the neural network to jump out of the local minimum, thus achieving the minimum
and improving the performance of the neural network.
QUALITY OF LIFE AND MENTAL EMOTIONAL HEALTH OF ELDERLY PEOPLE
Authors: Hany Alfrina
Published: December 2018

The higher dependence rate of elderly people in Ponorogo can make their quality of life lower.Unfortunately, how the quality of life can influence the mental emotional health is still unknown. The purpose of this research was to identify the influence of the quality of life to mental emotional disorders of older adults. The design of this research was Observational correlational Â with cross sectional approach. This research was held at 4 working areas of health facilities in Ponorogo district in East Java from March to May in 2015.This study included 200 elder people as participants and 50Â  sampling quota inÂ  each health facilities. The data collection in this study was assessed with 2 instruments. First instrument was used in this study developed by World Health Organization in Quality of life (WHO QOL-BREF) and second instrument was Self Reporting Questionnaire (SRQ).Â  The Pearson Correlation test was performed in this study (SPSS version 20) . The researchers found out that there was an influence of quality of life (physical health, psychologic, social relationship, and environment) on mental emotional disorders in elder people (p-Value < 0.05). Â This result revealed that quality of life in older adults influenced the mental emotional disorders. The improvement actions that can be proposed to decrease the mental emotional disorders of the elderly are the elderly are able to have an easy and quick access to health and general service facilities to support the mental well being of older people.
THE DIFFERENCES OF CORRELATION OF THE TIMI, GRACE, AND KILLIP RISK SCORES AS PREDICTOR PROGNOSIS PATIENTS WITH NON ST-ELEVATION MYOCARD INFARCTION ACUTE CORONARY SYNDROME IN ICCU RSUD DR.ISKAK TULUNGAGUNG
Authors: Anggraini Rina , Wihastuti Titin Andri , Kartikawatiningsih Dewi
Published: December 2018

Acute Coronary Syndromes is the leading cause of short-term and long â€“term mortality. An aggressive treatment approach has the potential to change the prognosis of patients with ACS, although its depends on risk factors. There are several risk scoresÂ  such as Thrombholysis in Myocardial Infarction (TIMI), Global Registry of Acute Coronary Events (GRACE), and Killip. The aim of this study is to analyse the differences of correlation of TIMI, GRACE, and Killip risk scores as predictor Length Of Stay patients with Non St-Elevation Myocard Infarction ACS. The method of this study utilized an analytic observational design with the cohort retrospective. The research was conducted at RSUD Dr.Iskak Tulungagung used 98 samples of medical records patient with NSTEMI ACS in the past 8 months (January-August 2017). The data collection techniques was completing risk score of TIMI, GRACE, and Killip and Length of Stay patient in ICCU ward. The results and analyse of Spearman Rank showed that TIMI has p = 0,000 r = 0.466,Â  GRACE p = 0,000 r = 0.598, and Killip p = 0,000 r = 0.441 (p < 0,05), so that it can be said that there wasÂ  significant differences between the risk score of TIMI, GRACE and Killip as predictor prognosis patient with NSTEMI ACS. It can be concluded that the TIMI, GRACE and Killip risk scores have correlation as predictor prognosis patient with NSTEMI ACS, which is GRACE risk score has superior to TIMI and Killip.
Del papel a la acción en la mitigación y adaptación al cambio climático: la roya del cafeto en Chiapas
Authors: Libert-Amico Antoine , Paz-Pellat Fernando
Published: December 2018

En el proceso de reconocimiento de los desafíos múltiples que el cambio climático presenta para la sociedad y el ambiente, la cantidad de estudios, planes y programas que discuten la mitigación y adaptación ha aumentado exponencialmente. Si bien un problema complejo como el cambio climático requiere soluciones complejas, persisten barreras a visiones interdisciplinarias y a la coordinación intersectorial. En particular, proyectos de gabinete (el papel) difícilmente llegan a la etapa de implementación (la acción), mientras que pocos contemplan las sinergias entre mitigación y adaptación. Este trabajo analiza planes y programas de respuesta al cambio climático para el sector cafetalero en el contexto de la epidemia de roya del cafeto, enfermedad provocada por el hongo Hemileia vastatrix que ha generado pérdidas importantes en producción de café desde el ciclo 2012/2013. Problemas estructurales crearon condiciones idóneas para esta enfermedad asociada al cambio climático, a la vez que la respuesta institucional ha generado nuevos desafíos para las comunidades cafetaleras que viven en zonas de alta biodiversidad como la Sierra Madre de Chiapas en el sureste de México. El escrito discute las sinergias entre mitigación y adaptación al cambio climático por medio del análisis de la campaña a favor de los acervos de carbono y la biodiversidad en cafetales bajo sombra de la Sierra Madre de Chiapas. Diseñada en respuesta a la presente epidemia de roya del cafeto, dicha campaña pone énfasis en la deforestación, la degradación forestal y la pérdida de servicios ecosistémicos que ha generado la actual crisis del café bajo sombra, con propuestas de atención que beneficien tanto a ecosistemas como a comunidades cafetaleras. Se identifican tres desafíos que marcan la distancia entre el papel y la acción, ejemplificados en el caso de la crisis cafetalera de la Sierra Madre de Chiapas.
Влияние beta-дикетонатного комплекса европия(III) на ориентационные отклики в сигнале сверхбыстрого оптического эффекта Керра-=SUP=-*-=/SUP=-
Authors: Никифоров В.Г. , Жарков Д.К. , Лапаев Д.В. , Шмелев А.Г. , Леонтьев А.В. , Лобков В.С. , Князев А.А. , Галяметдинов Ю.Г.
Published: December 2018

AbstractExperiments on recording the ultrafast optical Kerr effect (OKE) in solution of europium(III) β‑diketonate complexes in toluene at a concentration of 10^–2 mol/L showed that the total OKE signal is not a superposition of two contributions, one of which is related to the vibrational–rotational dynamics of toluene molecules, while the other is due to the vibrational–rotational dynamics of the europium(III) complexes. This immediately indicates that the europium(III) complexes essentially change the structure of liquid toluene, which is reflected in the character of an orientational response in picosecond range.