bluuebunny/crossref_metadata_2025 huggingface dataset:
Sporda Örgütsel Vatandaşlık Davranışı Ölçeğinin Türk Kültürüne Uyarlanması: Geçerlik ve Güvenirlik Çalışması
Authors: GÜNER Oğulcan , IŞIK Utku
Published: October 2023

Öz

Örgütsel vatandaşlık, olumlu sosyal (prososyal) örgütsel davranışın alt faktörlerinden biri olarak kabul edilmektedir. Spor örgütlerinde çalışan veya spor yapan bireylerin örgütsel vatandaşlık düzeyleri 90’lı yılların başından itibaren araştırmacılar tarafından sıklıkla incelenmiştir. Bu çalışmanın amacı spor bilimciler tarafından defalarca araştırmalara konu edilmiş olan örgütsel vatandaşlık kavramının, spora özgü olarak geliştirilmiş ölçme aracı olan “Sporda Örgütsel Vatandaşlık Davranışı Ölçeği-(SÖVDÖ)”’nin Türkçe formunun geçerlik ve güvenirliğinin test edilmesidir. Çalışmanın evrenini Türkiye’de farklı spor dallarında spor yapan bireyler oluşmaktadır. Çalışmanın örneklem grubunu ise kolayda örnekleme yöntemi aracılığıyla yaşları 15 ve üzeri (Xyaş=20,55±7,11) olan 307 katılımcı oluşturmuştur. Çalışmanın temelini oluşturan “Organizational Citizenship Behavior in Sport Scale” ölçeği 5 alt boyuttan (bağ kurma, toplum hizmeti, teşvik, ekstra çalışma, yardım etme) ve 22 maddeden oluşan 7’li Likert tipi (1=Kesinlikle Katılmıyorum, 7=Kesinlikle Katılıyorum) ile derecelendirilen bir ölçektir. Ölçek uyarlaması çeşitli aşamalardan geçmiştir. Öncelikle dilsel eşdeğerlik çalışması yapılmıştır. Ölçek daha sonra sırasıyla kapsam geçerliliği, yapı geçerliliği, yakınsak geçerlilik ve ayrışım geçerliliği analizlerine tabii tutularak son şeklini almıştır. Güvenirlik göstergesi olarak ise Cronbach’ s Alpha iç tutarlılık katsayısı hesaplanmıştır. Kapsam geçerliliği için Losche (1975) tarafından önerilen yaklaşım dikkate alınmıştır. Her bir madde için Kapsam Geçerliği Oranı (KGO) ve her ölçek faktörü için bir Kapsam Geçerliği İndeksi (KGİ) hesaplanmıştır. Hesaplamalar sonucunda her alt maddenin KGO'sunun 0,80'i, her faktörün KGİ'sinin ise 0,67'yi aştığı belirlenmiştir. Ölçeğin yapı geçerliliği doğrulayıcı faktör analizi ile test edilmiştir. Örgütsel Vatandaşlık Davranışı Ölçeğine ilişkin DFA sonuçlarına göre; modifikasyon indeksi, ilgili maddelerin dahil edilmesiyle model uyumunun teorik olarak iyileştirilebileceğini göstermiş ve bu nedenle model yeniden tanımlanmıştır. Toplam uyum indeksleri (GFI=0,901) ve karşılaştırmalı uyum indeksleri (CFI=0,940) önerilen eşik olan 0,90'ı aştı. Tahmin edilen hataların ortalama karekökü 0,054 olarak tespit edildi. Bu sonuçlar modelin verilere iyi uyum sağladığını göstermektedir. Ayırt edici geçerliği test etmek için MSV
Kardiyak Kataterizasyon Sonrası Gelişen Femoral Psödoanevrizmaların Ultrasonografik Kompresyon Yöntemiyle Kapatma İşlemi Sonrasındaki Kısa ve Orta Dönem Sonuçları
Authors: ŞAYLIK Faysal , SEVİMLİ Serdar
Published: October 2023

Amaç: Femoral arter yoluyla yapılan işlemlerden sonra psödoanevrizma gelişim riski sıktır. USG aracılı kapatma işlemi cerrahiye alternatif tedavi yaklaşımı olarak öne sürülmektedir. Bu calışma da psödoanevrizmalı hastalarda USG aracılı kapatma işleminin etkinliğini ve güvenilirliğini test etmeyi amaçladık.

Yöntem: Femoral arter yoluyla yapılan girişimlerden sonra psödoanevrizma gelişmiş olan 100 hasta retrospektif olarak çalışmaya dahil edildi. Tüm hastaların USG kayıtları, psödoanevrizmanın çapı, lobül sayısı ve kese boyun uzunluğu ile eni açısından incelendi. USG probu ile psodoanevrizma kesesi boynuna kompresyon uygulandı ve kese boynu tromboze olana kadar bası uygulandı. İlk bası ile kapanmayan hastalara ikinci ve üçüncü kez bası uygulandı.

Bulgular: Hastaların ortalama yaşları 61.9±12.6 idi ve hastaların %52`si erkekti. Çalışma grubunun %69`unu akut koroner sendrom, %25`ini stabil anjina pektoris, ve geri kalan %6 lık kısmını koroner olmayan hastalar oluşturmaktaydı. Hastaların %56`sına koroner anjiografi, %39`una perkütan koroner girişim ve %5`ine perkütan mitral balon valvuloplasti işlemi uygulanmıştı. 100 hastanın ilk yapılan USG kapatma işlemlerinde (ortanca 38 dk`lık kompresyon süresi) %80`ninde başarılı kapanma izlendi. Başarılı kapanma olmayan 20 hastaya yapılan ikinci USG kompresyonu (ortanca 40 dk`lık kompresyon süresi) sonucunda 12 hastada tam kapanma sağlanırken, 8 hastada tam kapanma sağlanamadı. Bu 8 hastaya üçüncü kez USG ile kompresyon (ortanca 40 dk`lık kompresyon süresi) uygulandı ve 5 hastada tam kapanma sağlandı. Sonuç olarak, hasta popülasyonunun %3`ünde (3 hasta) etkili USG kompresyonuna rağmen tam kapanma sağlanamazken, hastaların %97`sinde USG kompresyonu ile başarılı tam kapanma sağlanmıştır.

Sonuç: USG aracılı kompresyon yüksek (%97) başarı oranına sahiptir ve cerrahi tedavi yerine kullanılabilir.
Kadıkalesi Geç Bizans Dönemi Gömülerinin Mitokondriyel Kökenleri
Authors: TEPGEÇ Fatih , GÖRGÜLÜ Mehmet
Published: October 2023

Amaç: Sunulan çalışmada, Kadıkalesi Anaia kazılarından elde edilen, 13.- 15. yüzyıllar arasındaki insana ait biyolojik materyallerde aDNA elde edilip, Mitokondriyel DNA’dan maternal kökenlerinin tayin edilmesi planlanmıştır. Bu sayede bölgenin mitokondriyel haplogruplarının tespiti hedeflenmiştir.

Yöntem: Bu amaçla; 2016-2018 yıllarındaki açmalardan elde edilen ve Bizans dönemine tarihlendirilen 20 bireye ait kalıntılar incelenmiştir. Bireylerde önce antropometrik incelemeler yapılmış, ardından Sanger dizileme ile mitokondriyel HVR1 ve HVR2 bölgeleri incelendi. Elde edilen dizileme verileri online programlar vasıtası ile değerlendirildi.

Bulgular: Çalışmanın sonucunda 20 bireyden 12’si yaş, boy ve cinsiyet bakımından kimliklendirilmiştir. İnceleme sonucu 16 bireyin maternal haplogrubuna erişilmiş ve çoğunluğunun Batı Avrasya makrohaplogruplarından oluşmuş olduğu bulunmuştur. Buna ek olarak Sahra-altı haplogruplara sahip iki birey saptanmıştır. Grubun çoğunda post mortem DNA hasarı gözlemlenmiştir.

Sonuç: Sunulan çalışmada Kadıkalesi Anaia’daki geç bizans dönemi toplumunun yapısı hakkında hakkında genetik bilgi elde edilmiştir. Bu sonuçlar bölgede yapılacak diğer kazı alanlarında, dönemin toplum yapısının genetiğini öğrenmek için oldukça önemli bilgiler sağlayacaktır.
Evaluation of the Sacral and Coccygeal Curvatures Calculated via Computed Tomography Images Based on Gender
Authors: ÖZGEN Merve Nur , ÖNER Zülal , NAHİR Mert , ÖNER Serkan
Published: October 2023

Objective: The skeletal structure has a significant role in the estimation of human gender. The os sacrum and os coccyx bones that constitute the pelvic skeleton are important in sex estimation due to their functional differences based on sex. In the present study, we aimed to determine the differences in os sacral and os coccygeal curvatures calculated with orthogonal plane computed tomography images based on gender.

Methods: Computed tomography images of 150 healthy individuals (75 females, 75 males) between the ages of 25-50 were used in the study. The computed tomography images were edited into a suitable format by the Horos software for measurement. Six sacral and coccygeal measurements, lumbosacral angle (LSA), sacral curvature (SC), sacral kyphosis (SK), sacrococcygeal angle (SCA), sacrococcygeal joint angle (SCJA), and coccygeal curvature (CC) were conducted on the sagittal image.

Results: The measurement results indicated that LSA and SCA values were higher in male subjects when compared to females, and SCJA values were higher in females when compared to males (p≤0.05). Quadratic Discriminant Analysis (QDA) results indicated that these parameters were 93.3% effective in estimating male gender, 85.3% effective in estimating female gender, with an overall estimation rate of 89.3%.

Conclusion: According to these results, it was concluded that the lumbosacral and sacrococcygeal joints appear flatter in men than in women. SC, SK and CC parameters did not show sexual dimorphism. Considering all the parameters we used, we achieved a high rate of gender discrimination.
ÇOCUKLAR İÇİN ÖZEL GEREKSİNİM RAPORU (ÇÖZGER)’NA BAŞVURAN OLGULARIN PSİKİYATRİK TANI VE ÖZEL GEREKSİNİM DÜZEYLERİNİN ÖNCEKİ YÖNETMELİKTEKİ TANI VE ÖZÜR ORANLARI İLE KARŞILAŞTIRILMASI: RETROSPEKTİF ÇALIŞMA
Authors: TEMELTÜRK Rahime Duygu , UYGUN Sabide Duygu , CANLI Merve , EFE Ayşegül , GÜREL Yusuf , ÇETİNKAYA Miray , ÇAKMAK Fatma Hülya
Published: October 2023

Amaç: Bu çalışmada Çocuklar İçin Özel Gereksinim Raporu (ÇÖZGER)’na başvuran olguların sosyodemografik ve klinik özelliklerinin incelenmesi, psikiyatrik tanı ve özel gereksinim düzeylerinin eski yönetmelik ile karşılaştırılması amaçlanmıştır.

Yöntem: Çalışmamızda, Haziran 2019-Aralık 2019 tarihleri arasında Dr. Sami Ulus Kadın Doğum, Çocuk Sağlığı ve Hastalıkları Eğitim Araştırma Hastanesi sağlık kuruluna ÇÖZGER için başvuran ve psikiyatri ile ilgili herhangi bir alandan özel gereksinimi bulunan 6-18 yaş arasındaki çocuk ve ergenin dosya verileri geriye dönük olarak değerlendirilmiştir.

Bulgular: Çalışmaya %38’i (n=474) kız, %62’si (n=772) erkek olan 1246 olgu dahil edildi. Ortalama yaş 12,1±4,6 idi. Olguların %58 (n=723)’inde gecikmiş dönüm noktası, en sık olarak Hafif Düzeyde Zihinsel Yetersizlik (ZY) saptandı (n=459; 36,8%). Olguların %19,8 (n=247)’inde en az bir psikiyatri dışı alanda özel gereksinim varlığı tespit edilmiş olup en sık olarak hareket sistemi ve sinir sistemi alanlarından olduğu belirlendi (sırasıyla, n=156 ve n=88). ÇÖZGER sonrasında, eski sistemine göre Hafif Düzeyde ZY olgularında anlamlı bir azalma olduğu (χ2=19,41; p
Does Low Mean Corpuscular Hemoglobin Concentration Really Predict Mortality in Acute Exacerbations of Chronic Obstructive Pulmonary Disease?
Authors: KURT Hasret Gizem , ÇELİK Deniz , YILDIZ Murat , ERTAN Özlem
Published: October 2023

Background and Aim:

Several studies have shown associations of low mean corpuscular hemoglobin concentration (MCHC) with mortality and poor clinical course in conditions associated with chronic inflammation such as cardiac failure and COPD. Thus, in this study we aimed to determine the link between MCHC and readmission mortality in a large patient population with minimum 1 year of follow-up.

Methods:

Clinical data at admission, laboratory data, number of admissions to emergency room due to acute exacerbation of chronic obstructive pulmonary disease (AECOPD) following the discharge of the last patient recruited, number of admissions to pulmonology unit, and number of intensive care unit admissions between 2018 and 2019 were recorded. The follow-up duration ranged between 12 and 36 months.

Results:

A total of 339 patients were included. Based on a ROC analysis, the cut-off value for MCHC was 32.35 g/dl. Comparison of clinical data according to this cut-off value showed an increase in the incidence of pneumonia during admission, hypercapnic respiratory failure, need for non-invasive mechanical ventilation (NIV), and number of intensive care unit admissions within a 1 year period, as well as reduced survival in non-anemic subjects with MCHC ≤ 32.35 g/dL. In multivariate cox-regression analysis MCHC was not an independent predictor of mortality risk.

Conclusion: We recommend careful monitoring and assessment of comorbidities in AECOPD patients with low MCHC but without anemia. MCHC was not found to be an independent predictor of mortality but there was a significant correlation between MCHC and survival in patients without anemia.
Evaluation of Upper Extremity Venous Thrombosis with Doppler Ultrasonography in Peripheral Venous Line Applied Patients
Authors: HEZER Habibe , KILIÇ Hatice , ÖĞÜLMÜŞ Sevim , KARADUMAN YALÇIN Funda , HASANOĞLU Hatice Canan
Published: October 2023

Objectives: Peripherally inserted venous lines (PVL) may increase the risk of venous thrombosis due to vessel wall disarrangement. Aim of this study is to identify the cases of upper extremity venous thrombosis (UEVT) related to PVL since most of the PVLs applied to upper extremities.

Methods: Sixty-nine hospitalized patients with previous or present PVL insertions were included in this prospective study. Upper extremity Doppler compression ultrasonography (USG) examination were performed to on all patients. The cases with detected UEVTs were evaluated as group 1 and the remaining cases were evaluated as group 2. Demographic parameters, PVL applications, intravenous treatments were compared between the groups.

Results: UEVT was diagnosed by Doppler USG in 26 (37.7%) patients out of 69 patients. Lower extremity thrombosis was found in 10 (14.49%) patients. UEVT was observed in cephalic vein in 14 (53.8%) and in basilic vein in four (15.4%) out of 26 (37.7%) patients. Axillary and brachial deep UEVT was located in two (2.9%) cases. Superficial UEVT was found in 24 (34.8%) cases. Ceftriaxone, cefoperazone/sulbactam and esomeprazole were the mostly associated treatments with UEVT. UEVT was detected in five patients with PVL that were inserted only for drawing blood.

Conclusion: PVL is a risk factor for UEVT since almost 1/3 of the patients revealed UEVT. When PVL is no longer needed or the need for intravenous therapy decreases, oral therapy should be planned and PVL should be removed. Removal of PVL appears to be necessary to avoid UEVT.
Meclofenamic acid inhibits the invasion and migration of LNCaP prostate carcinoma cells by regulating vimentin expression
Authors: KANLI Aylin , YANAR Sevinc
Published: October 2023

Objectives: Despite various studies to improve the early detection and development of novel treatment agents, no significant progress has been made in the treatment of prostate cancer. Moreover, the metastasis of prostate carcinoma is a major challenge in treatment modalities. Therefore, in the present study, it was aimed to investigate the effect of meclofenamic acid (MA), a nonsteroidal anti-inflammatory drug, on the migration and invasion of LNCaP prostate carcinoma cells.

Methods: Firstly, the non-toxic concentrations of MA on LNCaP cells were determined by trypan blue exclusion assay. After that, the effect of MA on migration and invasion was assessed by wound healing assay and matrigel invasion assay, respectively. Finally, the expression level of vimentin, which is a marker for epithelial-to-mesenchymal cell transition, was assessed by western blotting.

Results: The results of trypan blue exclusion assay showed that 60 and 80 µM concentrations of MA were non-toxic to the cells. The migration rate of non-treated control cells was 44.4%, while it was significantly reduced to 12.9% and 2.9% in 60 and 80 µM MA-treated groups, respectively. When the cells were treated with 80 µM MA, the drug significantly reduced the invasion of LNCaP cells from 52% to 30.3%. Western blot results showed that the level of vimentin expression was significantly decreased in MA-treated cells.

Conclusion: The study shows for the first time that MA inhibits the invasion and migration of prostate cancer LNCaP cells by decreasing the expression level of vimentin.
Obezite cerrahisinde anestezi yönetimi: retrospektif çalışma
Authors: CESUR Sevim , ÇARDAKÖZÜ Tülay , YUCAL Nur Nazire , GÜLER Sertaç Ata
Published: October 2023

Amaç: Retrospektif çalışmada hastanemizde laparoskopik bariatrik cerrahi uygulanan hastalardaki anestezi deneyimimizin aktarılması ve perioperatif yönetimin literatür eşliğinde tartışılması amaçlanmıştır.

Gereç ve Yöntem: Obezite cerrahisi geçiren ASA II-III olan 72 Hasta retrospektif olarak değerlendirilmiştir. Hastaların demografik özellikleri, cerrahi süresi, peroperatif dönemde görülen komplikasyonlar (akut kidney injury-AKI), yoğun bakım ihtiyacı kaydedilmiştir.

Bulgular: Hastaların havayolu yönetiminde 7 (%10,3) hastada zor maske ventilasyon, 11 (%16,2) hastada zor entübasyon olduğu değerlendirilmiştir. İntraoperatif dönemde görülen komplikasyonlar arasında bradikardi, hipotansiyon görülmüştür. Ortalama cerrahi süre 135 dakika, cerrahi bitiminde 4 hasta yoğun bakım ünitesinde 24saat takip edilmiştir. Bu hastaların 2’sinde obstrüktif uyku apnesi sendromu (OSAS) tanısı vardı. Hastaların postoperatif 24 saatlik takiplerinde 1 hastada (%1,5) Akut kıdney injury (AKI) gelişmiştir.

Sonuç: Laparaskopik obezite cerrahisinde oluşabilecek komplikasyonların önlenmesinde preoperatif hazırlık, uygun peroperatif sıvı yönetimi ideal anestezi için gereklidir.
Proksimal Humerus ve Cavitas Glenoidealis'in Antropometrik Çalışması: Normal Glenohumeral İlişkiler
Authors: TUNCER Işık , BAYTOK Ahmet , DURMAZ Mehmet Sedat
Published: October 2023

Amaç: Omuz eklemi benzersiz düzensiz şekli nedeniyle karmaşık bir anatomik yapıya sahiptir. Omuz eklem bozukluklarının cerrahi tedavisi ve artroskopik işlemler gibi cerrahi müdahaleler için omuz ekleminin anatomisinin detaylı olarak bilinmesi gerekir. Ayrıca omuz ekleminde ırk veya cinsiyete bağlı morfometrik farklılıkların olup olmadığının bilinmesi antropoloji ve bazı klinik alanlarda özellikle adli tıpta faydalı olabilir. Ancak konunun önemine rağmen omuz ekleminin kantitatif anatomisine ilişkin az sayıda çalışma bulunmaktadır. Bu çalışmanın amacı omuz eklemi ölçülerini detaylı olarak sunmaktır.

Gereç ve Yöntem: Toplam 107 kişiye (54 erkek, 53 kadın) ölçüm yapıldı. 6'sı humerus proksimalinde ve 12'si cavitas glenoidealis'te olmak üzere 18 ölçüm yapıldı. Ölçümlerde MR cihazı kullanıldı. Cavitas Glenoidalis'in şekli (gözyaşı damlası, armut biçimli, yuvarlak, oval, ters virgül biçimli) değerlendirildi ve yüzdeleri hesaplandı.

Bulgular: Humerus proksimalindeki tüm değerler erkeklerde daha yüksekti (p40 ve
Böbrek Dokusunun Farklı Doku Takip Yöntemleri Kullanılarak Histolojik Olarak İncelenmesi
Authors: KARTAL Bahar , ALİMOĞULLARI Ebru
Published: October 2023

Amaç:Doku takibi genel olarak; fiksasyon, dehidrasyon, şeffaflandırma, sertleştirme ve doku gömmeyi içermektedir. Bu çalışmada doku bütünlüğünün korunması açısından, böbrek dokusunda dört farklı doku takibi yönteminin karşılaştırılması amaçlanmıştır.

Gereç ve Yöntem: 12 adet Wistar Albino ratlardan alınan 24 adet böbrek dokularına dört farklı doku takibi yöntemi farklı dehidratanlar (alkol ve aseton) ve farklı süreler ( 1 gün ve iki gün) uygulanmıştır. Elde edilen bloklardan alınan kesitler hematoksilen-eozin ve Masson trikrom ile boyanmış ve histomorfolojik olarak ışık mikroskobu altında değerlendirilmiştir. Bunlara ek olarak, dört farklı grupta böbrek glomerül çapları ölçülmüştür.

Bulgular: Böbrek preparatlarında glomerulus, tubulus distalis, tubulus proksimalis, inen henle, çıkan henle ve bowman kapsüllerindeki histolojik yapılar ele alınmıştır.Bu doğrultuda, böbrek dokusunda belirtilen bütün bölgeler için alkol ve aseton kullanılan gruplarda anlamlı bir fark olmadığı fakat iki gün süre ile aseton kullanılılan grupta böbrek doku bütünlüğünün bozulduğu saptanmıştır. Tüm gruplarda ölçülen böbrek glomerül çapları normal değerlere yakın bulunmuştur.

Sonuç: En iyi düzeyde histomorfolojik incelemeler için, doku takibi izlenmesi gereken önemli bir süreçtir. Bizde çalışmamızın sonuçları doğrultusunda dehidratif ajan olarak uygun süreler doğrultusunda aseton ve alkol kullanımını önermekteyiz.
Rare cause of small bowel obstruction: Wilkie's syndrome, a case report
Authors: ARSLAN Ramazan Serdar , ŞEMŞİT Mehmet Ali , DİKER Süleyman
Published: October 2023

Mechanical blockage of the bowel frequently causes abdominal pain, nausea, vomiting and distention. Post-surgical adhesions are the most common etiologies. Wilkie syndrome develops as a result of compression of the third part of the duodenum between the aorta and the superior mesenteric artery and it is extremely rare. The patients are mostly cachectic due to inadequate nutrition. Surgical intervention, especially duodenojejunostomy, is a preferred method in the treatment of the disease. Multidisciplinary approach is important in the diagnosis, treatment and management of the disease.
ÜNİVERSİTE HASTANESİNDE ÇALIŞAN DOKTOR VE HEMŞİRELERİN İZOLASYON ÖNLEMLERİNE UYUMLARININ DEĞERLENDİRİLMESİ
Authors: TÜNAY Havva
Published: October 2023

Amaç: İzolasyon önlemleri hastane enfeksiyonlarının azaltılmasında büyük rol oynamaktadır. Bu çalışma çalışan doktor ve hemşirelerin izolasyon önlemlerine uyumlarını değerlendirmek amacıyla yapılmıştır.

Yöntem: Çalışma Afyonkarahisar Sağlık Bilimleri Üniversitesi Tıp Fakültesi’nde çalışan 100 sağlık personeli (54 doktor, 46 hemşire) ile tanımlayıcı olarak yapılmıştır. Veriler katılımcıların sosyodemografik özelliklerini içeren anket formu ve izolasyon önlemlerine uyum ölçeği kullanılarak toplanmıştır. Ölçekten alınması beklenen minimum puan 18, maksimum puan 90’dır. Yüksek puan sağlık çalışanlarının izolasyon önlemlerine uyumunun arttığını göstermektedir. Veriler SPSS (Statistical Package for the Social Sciences) 22.0 istatistik paket programı aracılığı ile analiz edilmiştir.

Bulgular: Araştırmaya katılan hekim ve hemşirelerin yaş ortalamaları 25.99 ± 5.13 olup %66’sı kadındır. İzolasyon önlemlerine uyum ölçeğinden kadın personel %73.8 ± 10.17 ve erkek personel %66.52 ± 14.82 puan almıştır. İzolasyon önlemlerine uyum hemşirelerde daha yüksek oranlarda bulunmuştur. Katılımcıların %72’sinin izolasyon önlemlerine ilişkin eğitim aldığı saptanmıştır. Çalışmamızda eğitim alan sağlık personellerinin izolasyon önlemlerine uyum oranı %71.95±13.39 saptanmıştır. Eğitim alan sağlık personellerinde izolasyon önlemlerine uyum oranı daha yüksek bulunmuştur.

Sonuç: Çalışmada izolasyon önlemleri konusunda eğitim alanların ölçekten yüksek puan aldıkları belirlenmiştir. İzolasyon önlemleriyle ilgili eğitim programları geliştirilmeli ve bu eğitim tüm sağlık çalışanlarına verilmelidir.
INFLAMMATION IN NEWLY DIAGNOSED DIABETES PATIENTS
Authors: SARIÇAM Orkun
Published: October 2023

Objective. Type 2 diabetes mellitus (T2DM) is a chronic disease with an increasing prevalence, accounting for 90-95% of all diabetics. It is considered that the disease is induced by inflammation. In this study, we aimed to investigate the inflammation parameters and the relationship of these parameters with blood groups in newly diagnosed T2DM patients. Methods. The study included 80 newly diagnosed T2DM patients and 80 healthy volunteers. Demographic characteristics, body mass indexes (BMI), biochemistry and hemogram test results, C-reactive protein (CRP) values, and blood groups of the patient and control groups were recorded and compared between the groups. Results. The mean age was 51.64 years and 53.8% of the patients were male in the newly diagnosed T2DM group. The counts of white blood cells (WBC), neutrophils, lymphocytes, platelets, and monocytes, the values of the monocyte/HDL ratio (MHR) and the systemic immune-inflammatory index (SII), and the CRP levels of T2DM patients were statistically significantly higher than those of the control group (p
Effects of Long-Acting Methylphenidate Formulations and Atomoxetine on Cardiac Functions in Children with Attention Deficit And Hyperactivity Disorder
Authors: MUTLU MIHÇIOĞLU Ajda , KARA Tayfun
Published: October 2023

Objectives: Methylphenidate (MPH) and Atomoxetine (ATX) are most commonly prescribed for the treatment of Attention Deficit And Hyperactivity Disorder (ADHD). Despite their widespread use, there are concerns about their cardiovascular safety. In this study, we aimed to investigate the effects of ADHD medications on cardiac functions.

Methods: Forty-six children with ADHD disorder using osmotic-release oral system methylphenidate (OROS-MPH), 46 using extended-release methylphenidate (ER-MPH), and 46 using ATX for at least six months were included in the patient groups. 46 children with normal cardiac findings were included as the control group. All participants were evaluated using a sociodemographic information form, physical examination, 12-channel electrocardiography (ECG), transthoracic 2D echocardiography, Doppler echocardiography, and tissue Doppler imaging (TDI).

Results: Statistically significant differences were observed in terms of A wave velocity (p=0,002), E/A (p
Association Between Left Atrial Appendage Thrombus Formation and Monocyte/HDL Ratio in Patients with Acute Ischemic Stroke
Authors: ÇETİN Süha , VURAL Mustafa Gökhan
Published: October 2023

Objective: There is an apparent link between thrombus formation and inflammation. Monocyte/HDL ratio (MHR) has been determined as an inflammatory marker and associated with many cardiovascular disorders like coronary artery disease, acute coronary stent thrombus, coronary thrombus burden and atrial fibrillation (AF). The purpose of this study was to elucidate the association between MHR and left atrial appendage thrombus formation (AATF) in patients with acute ischemic stroke.

Methods: A total of 69 patients with the diagnosis of acute ischemic stroke were retrospectively enrolled in the study. Demographic, clinical and echocardiographic data were collected retrospectively from the patients’ records. MHR and neutrophil/lymphocyte ratio (NLR) were calculated from the present laboratory data.

Results: There was a significant positive correlation between MHR and NLR (r=0.6; p
Expression Levels of ACE2 and TMPRSS2 in Different Cell Lines
Authors: BAL ALBAYRAK Merve Gülsen , YANAR Sevinc , KASAP Murat , AKPINAR Gürler
Published: October 2023

Objective: ACE2 and TMPRSS2 proteins have received increased attention gained emphasis together with the pandemic COVID-19. These proteins have roles in respiratory and hypertension disorders as well as cardiovascular and renal diseases. The objective of this work was to examine the mRNA and protein levels of ACE2 and TMPRSS2 in cell lines derived from various tissue origins.

Methods: After the growth of 14 different cell lines, protein and mRNA were isolated from the cell pellets. The amounts of mRNAs and proteins were then determined and quantified using RT-PCR and ELISA.

Results: Findings showed that VERO, HEK293T, and VERO E6 cell lines significantly differed from others in the mRNA levels of both the ACE2 and TMPRSS2 genes. In protein levels obtained using ELISA, PNT1A cell line had the highest level of ACE2 protein expression, while for TMPRSS2, A549 had the highest level of protein expression.

Conclusion: It was showed in this study how the expressions of ACE2 and TMPRSS2 depend on the cell type. This may be an explanation for why virulence entrance differs in different types of tissues. It is thought that HEK293T cells with high levels of both genes may be a suitable option for studies at the RNA level by using these two genes. MCF7 may be a good option for studies at the protein level. Given the high levels of mRNA expression of both genes, it may be inferred that cells derived from the kidney were among those that were most susceptible to virus entry.
Kısa Bacak Atel Faaliyet Maliyetinin Zaman Sürücülü Faaliyet Tabanlı Maliyetleme ile Hesaplanması
Authors: ÖRS ONUR Tuğba , YILMAZ Recep
Published: October 2023

Amaç: Sağlık kurumları, zamanında, kaliteli ve sürdürülebilir sağlık hizmeti sunmak için, geri ödeme sistemleri de Sağlık Uygulama Tebliğ (SUT)’inde listelenen sağlık hizmet fiyatlarını doğru bir şekilde tespit etmesi için sağlık hizmeti maliyetlerinin doğru ölçülmesi gerekmektedir. Doğru hesaplanan sağlık hizmetleri fiyatları ve sağlık hizmeti maliyetleri ile olumsuz sapmaların önüne geçilerek yönetilebilir bir sistem kurulabilir. Bu çalışmanın amacı sağlık hizmetlerinin maliyetini güncel bir yaklaşım olan zaman sürücülü faaliyet tabanlı maliyetleme (ZSFTM) yöntemi ile hesaplayan bir model ortaya koymaktır.

Yöntem: İkinci basamak ilçe devlet hastanesi acil servisinde, kısa bacak atel sağlık hizmetinin maliyeti ZSFTM yöntemi ile hesaplanmıştır. Araştırma 2020 yılını kapsayan retrospektif bir vaka çalışmasıdır. Sağlık hizmetlerinin maliyetlerinin, SUT’ta açıklanan fiyatı ile karşılaştırma yapılabilmesi için hastanede gerçekleştirilen tüm giderler hesaplamaya dahil edilmiştir.

Bulgular : Kısa bacak atel faaliyetinin, direkt ilk madde ve malzeme birim maliyeti 43.68 TL, faaliyet maliyeti 61,40 TL, toplam birim maliyeti ise 105,08 TL olarak hesaplanmıştır. 2020 yılında SUT’da kısa bacak atel faaliyeti liste fiyatı ortalama olarak birim başına 28,9 TL’ dir. Çalışmada faaliyet maliyeti 61,40 TL olarak hesaplanmıştır. Çalışmaya göre, hastane kısa bacak atel faaliyetinden birim başına 32,5 TL zarar etmektedir.

Sonuç: Çalışmaya göre, hastane kısa bacak atel faaliyetinden zarar etmektedir. ZSFTM yöntemi, sağlık hizmeti maliyetlerini, güvenilir, doğru ve kolay hesaplayarak, sağlık hizmetlerinin kaliteli, zamanında ve sürdürülebilir olarak sunulmasını olanaklı hale getireceği düşünülmektedir. Sağlık hizmetlerinin maliyeti tek tek bu yöntem ile hesaplanarak, hangi faaliyetlerden kar, hangi faaliyetlerden zarar ettiği tespit edilerek gerekli önemler alınabilir.
EVALUATION OF CARDIAC AUTONOMIC DYSFUNCTION AND THE RISK OF ARRHYTHMIA IN CHILDREN WITH MITRAL VALVE PROLAPSE
Authors: BİNDAL Abdullah , DEVECİ Murat
Published: October 2023

Objective: The occurrence of symptoms in patients with mitral valve prolapse (MVP) is linked to autonomic dysfunction and neuroendocrine causes rather than progressive mitral valve insufficiency. The goal was to assess the risk of autonomic dysfunction and arrhythmia in patients with MVP.

Methods: The study included 63 patients with primary MVP and a control group of 64 children of similar age and gender. Following a physical examination, all patients' histories were taken, and 12-lead ECGs, autonomic function tests, echocardiography, and 24-hour Holter rhythm studies were performed.

Results: The patient group had a higher mean resting heart rate than the control group. Orthostatic hypotension was found in 8 patients (12.6%) and 4 children (6.2%) in the control group. When compared to the control group, patients with MVP had higher QTc dispersion, frontal QRS-T angle, Tp-e interval, and Tp-e/QTc ratio. There was no significant difference between the two groups in terms of conventional measurements of heart rate variability in the Holter ECG, as well as no significant difference in HRDC.

Conclusion: Although cases with pathological findings in the initial ECG were excluded from our study, we believe that the high frontal QRS-T angle observed in MVP patients is a novel and significant finding. Furthermore, it has been discovered that HRDC, a new and understudied parameter in children, does not show a significant difference in patients with MVP.
Effect of Drill Passing Down With Walls and Pairs Against Accuracy of Underpass in Volleyball Game
Authors: Ilhamdi Ilhamdi , Rahmat Ade , Porja Daryanto Zusyah
Published: October 2023

The  purpose  of  the study. This study aims to determine the difference in the effect of paired bottom passing exercises and bottom passing exercises reflected against the wall on the level of lower passing ability of MTSs YPPU Karimunting men's volleyball extracurricular participants, Bengkayang Regency.
Materials and methods. The design of this study is a two group pretest-post test design. The sample of this study was students participating in extracurricular men's volleyball MTSs YPPU Karimunting with a total of 30 students. The instrument used in this study was the bottom passing ability test. Data analysis techniques use t-tests through normality tests, homogeneity tests, and hypothesis tests.  
Results. The results showed: (1) There was a significant effect of paired bottom passing training on the level of lower passing ability of MTSs YPPU Karimunting men's volleyball extracurricular participants, it can be seen that t count is 2.131 > t table (1.746), while p value (0.000) < 0.05. (2) There is a significant effect of lower passing training reflected against the wall on the level of lower passing ability of MTSs YPPU Karimunting men's volleyball extracurricular participants, it can be seen that the results of the t test obtained t count of 2.160 > t table (1.771), while the p value (0.000) < 0.05.
Conclusions. These results mean that there is a significant effect of pair-bottom passing training on the level of lower passing ability of men's volleyball extracurricular participants at MTSs YPPU Karimunting, Sungai Raya Kepulauan sub-district, Bengkayang district.
Pengembangan Panduan Adobe Photoshop Cs6 Berbasis Android untuk Melatih Vokasional Life Skill Editing Gambar Siswa Tunarungu
Authors: Trimurti Nugrahanto Bimantara , Pamuji Pamuji , Purbaningrum Endang
Published: October 2023

Penelitian ini dilatarbelakangi oleh kurangnya kemampuan siswa tunarungu dalam penggunaan aplikasi komputer adobe photoshop CS6, karena belum adanya panduan khusus bagi siswa tunarungu dalam pengoperasian photoshop sehingga menyulitkan siswa tunarungu dalam proses editing gambar menggunakan photoshop CS6. Penelitian ini bertujuan untuk mengetahui kelayakan panduan pengembangan adobe photoshop CS6 berbasis android untuk melatih  vokasional life skill editing gambar siswa tunarungu. Metode yang digunakan dalam penelitian ini  adalah 4D dengan tahapan Define (Pendefinisian), Design (Perencanaan) Develop (Pengembangan) dan Disseminate (Penyebaran). Teknik pengumpulan data dilakukan dengan menggunakan lembar validasi ahli yang meliputi ahli media, ahli materi, serta pengguna. Data hasil kelayakan berdasarkan uji validitas dari beberapa ahli diperoleh hasil (1) Ahli materi Pendidikan Luar Biasa 75%, (2) Ahli Media 95%, (3) Menurut pengguna 95%. Dapat disimpulkan bahwa pengembangan panduan Adobe Photoshop CS6 berbasis android untuk melatih vokasional life skill editing gambar siswa tunarungu layak untuk digunakan.
Detection and characterization Salmonella enterica from broiler chicken(Rose308) in Thi-Qar province and its relationship to broiler immunity and body weight
Authors: Hassan Ghargan Noor , Abdulkareem Ali A. , Kareem Hanan Zaman
Published: October 2023

This study was conducted to isolate Salmonella bacteria from broiler (ROSS 308). A total of 184 stool samples were collected from chickens, showed symptoms of infection with salmonella bacteria from two different fields in Thi-Qar Governorate in Al-Islah district and Al-Fadeliyah district. Thirty isolates (16.2%) were diagnosed with Salmonella infection by biochemical and API 20 E tests. The pathological infection was confirmed in chickens by analyzing the level of antibodies in the blood of chickens, there was an increase in the level of immunoglobulin IgG and IgM, confirmed the existence of the disease and the stage of infection between a new infection and the acquisition of immunity, as a result of the previous injury and injuries close to recovery. The birds that suffer from a lack of weight differed in the stage of infection, this indicates that infection at any stage has a significant impact on the weights of birds infected with salmonella bacteria.
Study of the concentration level of heavy metals in water and some tissues of common carp, Carpinus carpio L. which is cultured in cages in the Euphrates River
Authors: Jasim Ruaa Mohammed , Kamil Kadhim Fahad
Published: October 2023

The current study included measuring some chemical and physical properties of the water of the study area and estimating the concentration of three heavy elements (lead, copper, and zinc) in the tissues of the common carp (Gills, muscles, and viscera) of Cyprinus carpio L. Samples were collected from one of the private farms that raise fish in floating cages on the Euphrates River from 11/18/2022 to 4/18/2023. The study also included measuring water temperature, air, turbidity, electrical conductivity, total dissolved solids, pH And dissolved oxygen samples taken from the water were analyzed as well as samples taken from fish tissues on a monthly basis. The results of the study showed that the air temperature ranged between(6.8-10.2)C. Water temperature (17_33), turbidity (6.8_10.2), electrical conductivity (1.04_2.13), total dissolved solids (7752_18730) mg/l, and pH value (7.2_7.82) between neutral to lightly basic. The dissolved oxygen value ranged between (6.78 - 7.92) mg/l during the months of the experiment. The standard methods were used to estimate the concentration of heavy metals in water and tissues by flame atomic absorption spectrometer. The results showed that the highest total concentration of lead, copper and zinc was recorded in the water during the winter season (1.533, 2.300, 6.700) µg/L. Recorded in tissues for lead in the gills and viscera, the highest values were in spring (9.533, 6.500) µg/L, respectively. Copper recorded the highest value in the gills and viscera, respectively, and the concentrations were high in the autumn season (16.793, 18.723) µg/g dry weight, respectively. g dry weight respectively, the results showed that the accumulation of heavy elements was in the following order .                                                                                        

Concentrations in the water are zinc < copper < lead

And in the tissue as follows            

Gills < muscle < viscera   lead  

gills < viscera < muscle copper  

Zinc        gills < muscle < viscera

Different densities were also studied to obtain the best culture density. Three densities (21_25_28 fish / m3) were used, with 500 fish for the first treatment, 900 fish for the second treatment, and 1100 fish for the third treatment, with an average weight of (120_140) g. Diet of Iranian origin was used for the three treatments. The results of the statistical analysis showed that there were significant differences during the months of the study, where the highest rate was in the month of March.
The effect of plowing depth and distance between the two beds of furrows opener developed under different tillage systems on some soil physiology and sunflower crop growth
Authors: Al batat Diaa Adnan Hameed , Majed Salih Himoud
Published: October 2023

Abstract:

The research was conducted in clayey loamy soil using two plowing systems (T1 chisel) and (T2 moldboard) and three depths of plowing D (10, 20, 30 cm) and three spacing between the two plates of each of the furrows opener (40, 50, 60 cm). ) to study the effect of the developed furrows opener on the physical properties of the soil (bulk density and porosity) and the growth characteristics of the sunflower crop (plant height, , productivity,)

The furrows opener, when used after the moldboard plow, gave the highest height and the maximum quantity of the total seed yield of the plant, while the three mentioned traits recorded the highest increase at the maximum depth of the stalk (30 cm) and the largest spacing between the boards (60 cm) between the two plates of each of the three The furrows opener weapons, and the traits were affected (Plant height and total seed yield) were significantly affected by the bilateral and triple interactions between the study factors (tillage systems, machine depth, and the distance between the two plates) .While it affected some of the physical soil characteristics represented by the bulk density of the soil and the total porosity of the soil, the sander recorded a decrease in the apparent soil density when used after the chisel plow, and also decreased with the increase in the depth of the machine and with the increase of the inter-distance between the boards of furrow opener, while the bilateral interference was recorded between systems Tillage and tillage depth had a significant effect, while the binary interactions between (tillage regimes spacing between the boards, plow depth, and spacing between the boards) and the triple interaction between the study factors (tillage regimes, plow depth, and spacing between the boards) had no significant effect on bulk density. The developed plow excelled when used after the chisel plow by recording the highest total porosity, which increased with increasing the depth of the machine and increasing the inter-distance, while the bilateral interference between the tillage systems and the depth of the machine had a significant effect, while the bilateral interactions between (the tillage systems and the inter-distance, the depth of the machine and the inter-distance ) and the triple overlap between the study factors (tillage systems, machine depth and spacing between the boards) any significant effect on the total porosity of the soil.

Keywords: plowing systems, the depth of the machine (the depth of plowing), the distance between the furrow opener plates.
Effect of fermented soybean meal with probiotic and beta-glucan on some physiological and microbial traits of broiler chickens
Authors: Karim Noora , Al-Asadi Majid
Published: October 2023

The study aimed to investigate the effect of fermented soybean meal with probiotic and beta-glucan on some physiological and microbial traits of broiler chickens. The study was conducted from 12/2/2022 to 2/5/2022, at the animal field of the College of Agriculture, University of Basrah. This study included the manufacture of a device for fermenting soybean meal to raise its nutritional value by fermenting it, with probiotics or with beta-glucan. A total of  225 unsexed chicks, one day old, 40 gm broiler chickens Ross308 were used, they were prepared from one of the private hatcheries in Basra Governorate. The chicks were distributed randomly to five treatments, with three replicates (15 chicks per replicate), according to the Complete Random Design (CRD), the treatments were as follows; T0: Control treatment (basal diet), T1: added soybean meal with the addition of 0.5g/kg probiotics (without fermentation) to the basal diet. T2: added soybean meal with the addition of 0.5 g / kg+ 0.2% betaglucan (without fermentation) to the basal diet. T3: added fermented soybean meal with probiotic 0.5g/kg to the basal diet. T4: added fermented soybean meal 0.5g/kg+ 0.2% betaglucan to the basal diet. The results showed a significant increase in the percentage of total protein, albumin, globulin, and the number of lactobacillus bacteria, with a decrease in coliform bacteria of the fermented treatment and fortified with probiotic and beta-glucan compared to the control and non-fermented treatment.
Molecular and biological Study of Colibacillosis Susceptibility in broiler
Authors: Hassan Zaher  , Balqees Hassan Ali
Published: October 2023

This study was aimed to Detection of virulence genes(rfbE) It was carried in College of Veterinary Medicine at Baghdad university, During a time span of November (2021) to March (2022). (100) samples were collected from diarrheal chicken . 100 chicks were used in the present study, One day old chicks were weighed (Average of chick weight was 160 gm±2) then transferred to the poultry house. Chicks in wards that were divided by wood barriers. Diagnosis of bacterial colonies were first done by the bacteriological methods. From (100) fecal samples of diarrheal cases of chicken , 90(90%) isolates were Escherichia coli.In the present study using vitek 2 compact system and Api 20 Escherichia coli. for the identification isolated bacteria. PCR technique was used to Detection of virulence genes(rfbE) ,The result for rfbE gene in this study was showed that this gene was detected in(60) isolates of (90) samples of chicken observed carried the rfbE gene which represent (67%).
Assessing the Climate Performance Potential of Start-ups: Insights and Guidance on Environmental Sustainability Assessment of Young Ventures
Authors:   Chair of Sustainable Engineering, Institute of Environmental Technology, Technische Universität Berlin, 10623 Berlin, Germany, Diekel Felice , Bach Vanessa ,   Chair of Sustainable Engineering, Institute of Environmental Technology, Technische Universität Berlin, 10623 Berlin, Germany, Finkbeiner Matthias ,   Chair of Sustainable Engineering, Institute of Environmental Technology, Technische Universität Berlin, 10623 Berlin, Germany
Published: October 2023

The role of early-stage venture capital (VC) investment in financing for ambitious climate action is often overlooked. In the developing field of climate-tech investment, one of the biggest challenges is to identify the start-ups and business models that contribute to climate change mitigation. The potential of a start-ups business model to reduce greenhouse gas emissions is defined as the start-ups climate performance potential (CPP). The assessment of a start-up’s CPP could enable start-ups and VC investors to invest in a more informed way with greater precision, impact, and purpose. The objective of this paper can be expressed in two steps: First, to gain insights into and identify the potential for improvement in the environmental sustainability assessment practices of VC firms through an exploratory case study. Second, to provide life cycle-based guidance on environmental sustainability assessment of innovative products offered by start-ups to determine their CPP, by eliciting appropriate criteria and procedures for directionally sound assessment. For this, the assessment approach developed by the climate-tech VC firm World Fund was used for the exploratory case study. In a first step, the CPP assessment process was described, based on document review and observation. Next, the CPP carbon footprint method was compared with ISO standardizations of life cycle assessment (LCA) and carbon footprint (CF) along eight criteria. Development potential was identified and discussed for seven of the eight criteria, including, for example, the use of scenarios, the complexity of meta-analyses, and the need to avoid misleading incentives.
Excavation, emersion, permanence-- A case study of renaissance and renewal of historic blocks along the Grand Canal in Hangzhou
Authors: Zhou Liya
Published: October 2023

This paper studies the urban renewal planning and construction of the historic districts along the Beijing-Hangzhou Grand Canal in Hangzhou, taking the two cases of Qiaoxi Historic District and Dadu Road Historic District as the objects, and analyses the planning and design strategies and specific practices of urban renewal and restoration. From the perspectives of economic, social and environmental sustainability, it summaries the successful experience of old city development along the canal in Hangzhou and puts forward further suggestions.
Study and simulation of thrombus properties
Authors: Fang Huihui , Dong Jing , Wei Chen , Zuo Yangjie
Published: October 2023

Thrombosis is a common pathological symptom that endangers cardiovascular and cerebrovascular health, and its essence is that blood clots in the vascular wall cause serious problems in the body. In vitro simulation of thrombosis can help us understand the composition and nature of thrombosis, and provide basis and convenience for better thrombus removal technology. This paper will discuss the existing thrombosis simulation methods and their development, and propose a new in vitro simulation of thrombosis preparation.
Overview of Scientific Advancements in Implementation Science
Authors: Zhou Yilin
Published: October 2023

Implementation science is a systematic research methodology aimed at facilitating the application of research findings and other evidence-based practices into clinical daily routines. It has become highly relevant to scientific research. As the concept of "implementation science" deepens, related theories and practical methods continue to evolve, leading to rapid advancements in implementation science. However, in China, there has been limited application and slower development of implementation research. This study approaches the subject from a problem-oriented perspective and systematically describes several commonly used theoretical frameworks, methodologies, implementation strategies, and applications in implementation research. The goal is to support the development of implementation science in China, promote its integration into evidence-based medicine, and provide reference materials for conducting implementation research more effectively.