bluuebunny/crossref_metadata_2025 huggingface dataset:
Kajian Ulum al-Qur’an dalam Pandangan Mufassir Nusantara Tgk. Hasbie Asshidiqie
Authors: Kusuma Agung Perdana
Published: March 2022

In this paper, it contains the opinion of the mufassir nusantara in using the ulum al-Qur'an method applied to the commentary. Hasbie Ash-Siddiqie in his An-Nur commentary also uses the ulum al-Qur'an method. Not all the methods in ulum al-Qur'an are explained in this paper. Only a few examples of this method, the view of Hasbi Ash-Siddiqie applies in his commentary. The method used in this paper is a description-analysis that describes the problem associated with obtaining a comprehensive understanding. It starts with reading the life history of Hasbi Ash-Siddiqie. Then the background of the commentator in writing the commentary. After that, the speaker will analyze through ulum al-Qur'an from Hasbi Ash-Siddiqie. The data collection technique used in this research is literature study (Library Research). Then the data is analyzed qualitatively.
Differentiating Eosinophilic Esophagitis and Eating/Feeding Disorders
Authors: Cifra Nicole , Lomas Jeanne M.
Published: March 2022

Eosinophilic esophagitis (EoE) is an inflammatory condition of the esophagus that causes symptoms of esophageal dysmotility. Patients with feeding or eating disorders (ED) can have similar symptoms, and there is a paucity of literature exploring these similarities. Furthermore, EoE can occur in addition to an ED, requiring clinicians to obtain a thorough history, make accurate diagnoses, and adequately treat all underlying conditions. We present 4 pediatric cases highlighting the similarities between EoE and ED symptomatology. Patients 1 to 3 were presumed to have an ED and were subsequently diagnosed with EoE. Patient 4 had a history of previously diagnosed and inadequately treated EoE, but was later found to also have a longstanding ED. The patients presented to the University of Rochester Pediatric Ambulatory Clinics in 2020. This series demonstrates that symptoms of EoE can overlap with those of an ED, such as anorexia nervosa or avoidant restrictive food intake disorder. Therefore, assessment for either EoE or an ED should include questions related to both diagnoses. Symptoms that may raise suspicion of EoE are indigestion, acute (versus chronic) weight loss, and dysphagia, including the inability to swallow pills, particularly in the presence of personal or family history of atopy. Patients with known EoE should be periodically evaluated for the presence of an ED. This case series illustrates that EoE can either present as an ED or complicate the diagnosis and/or treatment of an ED, making prompt diagnosis and treatment essential for successful management of all conditions.
Modelación de crecimiento urbano: Tunja 2017 – 2035
Authors: Rojas Gamba Nestor Ivan , Fonseca Salamanca Liby Angelica , Pérez Rueda Sandra Liliana , Blanco Suarez Miguel Alfonso
Published: March 2022

Se cuantifican tendencias de aumento de suelo urbanizado en la ciudad de Tunja, Colombia, para modelar escenarios futuros. El modelo se basa en clasificación de imágenes satelitales y la inclusión de factores influyentes en el urbanismo. Se visualizan las zonas probables de futuro desarrollo, mediante las siguientes etapas: 1). Pre procesamiento, define la zona de estudio y adecúa las imágenes. 2). Procesamiento, clasifica las imágenes 2000, 2012 y 2017, genera mapas de coberturas y usos: urbanizado, zona verde y área abierta. 3). Post procesamiento, valida la precisión de la clasificación. 4). Modelamiento de escenarios futuros, incorpora los factores de cambio hacia suelo urbanizado y las restricciones, genera un análisis de cambio y uno de áreas potenciales de transición a territorio urbanizado, para crear los modelos predictivos 2017, 2025 y 2030. El modelo se valida comparando la predicción 2017, con la imagen de clasificación del mismo año, modificando factores hasta que la imagen de predicción 2017 sea representativa de la imagen producto de clasificación. La clasificación y los escenarios futuros son herramientas para desarrollo y gestión, facilitan evaluar legalidad de ocupación, calidad de construcciones y dinámicas de crecimiento para planeación.
Ordenamientos para la paz en el San Juan, Chocó
Authors: Cantor Avila Vivian Andrea
Published: March 2022

La investigación analizó la relación entre los órdenes territoriales y la implementación del Acuerdo de Paz en la cuenca media del San Juan, enfocándose en la formulación de los PDET y la gestión de diversidad de territorialidades y nociones de paz territorial. Metodológicamente, se optó por un enfoque cualitativo de triangulación hermenéutica que permitió contrastar las voces de diferentes actores. Se identificó que la construcción e implementación de los PDET tiene por lo menos tres grandes retos en materia de ordenamiento territorial: la presencia de actividades mineras desde el periodo colonial, práctica que se ha transformado hasta la actualidad, donde predomina la minería mecanizada ambiental y socialmente insostenible; la sobreposición de distintas figuras de administración y ordenamiento territorial, y el carácter mayoritariamente étnico de la población que representa una territorialidad diferente tipificada como agrominera. La formulación del PDET se presenta como escenario de encuentro de territorialidades y de nociones de paz, en el que existen dificultades de articulación de diferentes visiones, así como problemas en el reconocimiento del contexto geohistórico minero en el cual se territorializa la política pública, lo cual ha dado paso a la imposición de lógicas y espacialidades estatales en los territorios afectados por el conflicto armado.
Desafíos de la planeación en los territorios del posacuerdo
Authors: Cárdenas Noriega Darly Jazmín
Published: March 2022

El Acuerdo Final, firmado entre el Gobierno Nacional y las Fuerzas Armadas Revolucionarias de Colombia (FARC-EP) en 2016, impulsó una nueva etapa de entendimiento y construcción de los espacios, acontecida por la confluencia de dos procesos. Primero, la reconfiguración territorial dada por la instalación de los Espacios Territoriales de Capacitación y Reincorporación -ETCR- para la transición a la vida civil de las FARC-EP, los cuales van adquiriendo sentido propio desde las estrategias de sobrevivencia mediante la organización, la gestión del conocimiento, y la planificación local. Segundo, la materialización del nuevo sentido de la planeación desde la asunción del enfoque territorial, que integra el territorio como unidad de referencia en la intervención institucional. Los dos procesos han sido agenciados de manera diferencial, lo que ha ocasionado que los territorios del posacuerdo oscilen entre la supervivencia y la reivindicación de reconocimiento. En el presente artículo se mostrará el desafío de la planeación con enfoque territorial para el reconocimiento de los territorios del posacuerdo, a partir del estudio de caso Antiguo Espacio Territorial de Capacitación y Reincorporación Jaime Pardo Leal, Guaviare. Desde una perspectiva interdisciplinaria, se articula la teoría del territorio de la geografía y la propuesta metodológica Actor-Red del sociólogo Bruno Latour.
La ‘pacificación’ y la ‘paz territorial’ en Urabá como lógicas espaciales de la paz
Authors: Álvarez-Giraldo Ever Estyl , Pimienta Betancur Alejandro
Published: March 2022

Este artículo analiza la formación de dos lógicas espaciales de la paz, a partir de resultados de investigación en la región de Urabá (Colombia). Inicia revisando la formación histórica de una lógica espacial de la paz que asoció a Urabá con una región de frontera que debía ser sujeto de pacificación para dar paso a la materialización del orden hegemónico capitalista y de inclusión al territorio del Estado nación. Acto seguido, el artículo analiza algunos ordenamientos espaciales que subyacen en la lógica espacial de la ‘paz territorial’ que emergió con la perspectiva gubernamental de implementación del Acuerdo de Paz, y que se superpone a aquella lógica de la pacificación hegemónica. A partir de una estrategia metodológica que articula el estudio de caso y la etnografía multilocal, se concluye que la paz territorial tiene una versión estatal y normativa que no supera la lógica de la pacificación. Sin embargo, hay otra paz territorial que se configura como proyecto político antagónico y potencia las capacidades en los actores, pero que encuentra limitaciones ante la profundización de los desequilibrios socioespaciales derivados de la reconfiguración del conflicto armado, de la presencia fragmentada del Estado y de intervenciones económicas lícitas e ilícitas.
Conflicto sociopolítico, minería, impacto ambiental, comunidades
Authors: Monsalve Friedman Luz Marina
Published: March 2022

Algunas de las causas del conflicto sociopolítico en Colombia se asocian a las condiciones de desplazamiento forzado y muertes violentas por la presencia de proyectos mineros, hay impactos ambientales en los ecosistemas, cambios en la dinámica territorial y las comunidades quedan afectadas por los efectos del conflicto.

Los diferentes grupos armados se disputan el territorio para poder negociar un pago por permitir la operación del proyecto, esta situación es reconocida en distintas zonas del país con presencia minera, es una condición con la que conviven las comunidades en zonas mineras, las muertes por líderes ambientales se incluyen en estos conflictos y se relacionan a la defensa de los bienes comunes donde los líderes terminan por ser víctimas del conflicto minero ambiental.
Tecnologia de informação para atendimento de urgência e emergência: Revisão integrativa.
Authors: Mendonça Renata Rodrigues , Neves Igor Fernando , Costa Maria Antonia Ramos , De Souza Verusca Soares , Fernandes Carlos Alexandre Molena
Published: March 2022

Objetivo: Identificar na literatura científica as tecnologias desenvolvidas para integração e otimização dos serviços de urgência e emergência.
Metodologia: Trata-se de uma revisão integrativa de literatura. Para seleção dos artigos, utilizou-se acesso on-line nas bases de dados MedLine, PubMed, Lilacs; Scielo; BVS; Science Direct; Cochrane Library; Scopus e o buscador Google Acadêmico, publicados no período de 2011 a 2019, e a coleta de dados ocorreu de outubro a dezembro de 2019. A análise dos dados ocorreu mediante a leitura exploratória, seletiva, analítica e interpretativa dos artigos e os resultados foram apresentados sob a forma de quadros.
Resultados: Identificou-se que nos 11 artigos selecionados dentre as tecnologias elencadas principalmente as classificadas como “dura” contêm múltiplas funções, inclusive registro de dados clínicos, monitorando o serviço médico, cálculo programado de medicações, tele radiologia entre outros serviços que propiciam a otimização dos serviços prestados dentro da Rede de Atenção às Urgências e Emergências
Conclusão: Os estudos mostraram que as tecnologias digitais, são uma ferramenta adequada para apoiar as práticas do cuidado ao paciente crítico dentro dos serviços de atendimento de urgência e emergência. Verificou-se também que os aplicativos móveis podem ser eficazes, pois foram considerados úteis no acompanhamento da dor, manejo clínico de especialidades, preparo de medicamentos, mapeamento de áreas críticas, classificação de risco, reprodução de exames de imagens assim como no auxílio aos clientes no que se diz respeito a fornecer informações sobre a ordem e rapidez do atendimento.
Efeitos simbólicos da implantação da casa de saúde indígena: um estudo histórico
Authors: Amorim Raphael Florindo , Silva Paulo Sergio da , Machado Jacquelaine Alves , Zambonin Fernanda , Brito Amanda Ramos de , Bethonico Maria Bárbara de Magalhães
Published: March 2022

Objetivo: Descrever os efeitos simbólicos da implantação da Casa de Saúde Indígena no campo da saúde no período de 1973 a 1983 em Boa Vista, Roraima, Brasil.
Metodologia: Trata-se de um estudo histórico com abordagem da micro história orientado por análises documentais e a teorização dos resultados balizada nos conceitos do sociólogo Pierre Bourdieu.
Resultados: Ao todo o corpus documental foi representado por quatro registros imagéticos. As imagens foram analisadas com o intuito de produção de reflexões que versam sobre os efeitos simbólicos de implantação da Casa de Saúde Indígena.
Conclusão: A Casa de Saúde Indígena de Boa Vista-RR emerge como pano de fundo no cenário desenvolvimentista da época, como (e representou) moeda de troca simbólica entre os governantes e os indígenas que sofriam com a entrada de doenças em suas comunidades pela ação direta do processo migratório devido ao garimpo em suas terras.
Selective Dorsal Rhizotomy in Treatment of Spasticity in Patients with Cerebral Palsy
Authors: Klochkova Olga A. , Kolesnikova Ekaterina P. , Zinenko Dmitriy Yu. , Berdichevskaya Evgeniya M.
Published: March 2022

Selective dorsal rhizotomy (SDR) is effective and safe neurosurgical method for the treatment of patients with spastic forms of cerebral palsy (CP). The aim of the review is to introduce the opportunities of SDR in CP patients, to present indications, contraindications, and current inclusion criteria for the surgery for the broad audience of specialists. Authors have given recommendations on SDR implementation in complex rehabilitation of CP patients and have defined its effective combination with other methods of spasticity treatment according to the international experience of SDR, and its short-term and long-term results. The particular attention was paid to the application of SDR in cases of secondary orthopaedic deformities due to CP. The understanding of opportunities and limitations of SDR will allow us to give the patients relevant help and use the advantages of this method.
Fossil Fuel Fiction and the Geologies of Race
Authors: Tanaka Shouhei
Published: March 2022

This essay argues for an energy literary criticism that centers the problem of the energy epoch as the problem of the color line. It does so by reading a set of novels—Helena María Viramontes'sUnder the Feet of Jesus(1995) and Colson Whitehead'sZone One(2011) andThe Underground Railroad(2016)—as fossil fuel fictions that illuminate the conjuncture of energy and racial capitalism. These works unearth the racialized world making of extractive energy regimes by articulating energy's social production of race across the colonial histories and geographies of the Anthropocene. The entanglement of racialized bodies and hydrocarbon matter across biological, historical, and geological time scales in these novels formalizes what Kathryn Yusoff calls the “geologies of race.” Excavating the racial infrastructures scaffolding the Anthropocene's power grids, Viramontes's and Whitehead's georacial imaginations envision decolonial and abolitionist energy futures for Brown and Black lives.
Waiting for Godotand the Racial Theater of the Absurd
Authors: Vogel Shane
Published: March 2022

This essay argues that the 1957 Black-cast revival of Samuel Beckett'sWaiting for Godotstages an Africana absurd sensibility that precedes and supersedes European philosophies of absurdism. While the Continental absurd developed as a repudiation of Western reason and aspired to a universalizing assessment of the human condition, the Africana absurd is situated in the historical formation of racial slavery and colonialism. More specifically, the Africana absurd is a response to the formal meaninglessness and incoherencies of Western racial logic. Locating it within the existential and historical situation of Black theater in the Jim Crow era and attending to theatrical elements such as casting, stage props, and choreography, this essay shows how the production recasts Beckett's absurdism, metatheatricality, and antihumanism to present, rather than represent, the felt absurdity of racial modernity.
Cartooning with Compassion: A Conversation with Megan Herbert
Authors: Priego Ernesto
Published: March 2022

This article presents the outcome of a semi-structured interview with Australian writer and illustrator Megan Herbert. Conducted online, the conversation revolved around Herbert's cartooning work published online during 2020 and 2021. The annotated transcription offers insights into process, personal and professional issues in freelance cartooning, and the challenges and opportunities of cartoon publishing on social media. This article offers qualitative data that can be useful for researchers interested in the history, techniques, and current developments of cartooning, and for cartoonists interested in the experience of fellow professionals during pandemic times.
Emotional (Tech) Support: Sexualised Care Work and Robotic Sexualities
Authors: Erhard Constanze
Published: March 2022

AI-equipped sexbots are framed as 'perfect companions'. However, the question arises as to what kind of companionship the conception and consumption of these sexbots entails. This article explores the structural position of sexbots and the specific concepts of sexuality, intimacy and care connected to it. It argues that sexbots are providers of sexualised care work, a convergence that needs to be understood in the broader analysis of sexuality and care in post-industrial theories of sexuality. Through its promise of sexual fulfilment, emotional support and care, the sexbot enforces masculinities and does therefore not represent a posthumanist project (at the moment).
[RETRACTED] Coral CBD Gummies Reviews: Effective Ingredients That Work? - Shocking Side Effects Revealed v1
Authors: CBD Gummies Coral
Published: March 2022

[RETRACTED]

Coral CBD Gummies
[RETRACTED] Early Bird Lemon CBD Gummies Reviews - Gummy Candy 2022 v1
Authors: not provided earlybirdlemonreviews
Published: March 2022

[RETRACTED]

Early Bird Lemon CBD Gummies Reviews - Gummy Candy 2022
High resolution respirometry of isolated mitochondria from adult Octopus maya (Class: Cephalopoda) systemic heart v1
Authors: Karen Meza-Buendía Ana , Emiliano Aparicio-Trejo Omar , Díaz-Herrera Fernando , Caamal-Monsreal Claudia , Pedraza-Chaverri José , Álvarez-Delgado Carolina , Paschke Kurt , Rosas Carlos
Published: March 2022

Mitochondrial respirometry is key to understand how environmental factors model energetic cellular process. In the case of ectotherms, thermal tolerance has been hypothesized to be intimately linked with mitochondria capability to produce enough adenosine triphosphate (ATP) to respond to the energetic demands of animals in high temperatures. Recent studies made in Octopus maya proposed the hypothesis postulating that high temperatures could restrain female reproduction due to the limited capacity of the animals’ heart to sustain oxygen flow to the body, affecting in this manner energy production in the rest of the organs, including the ovarium. Until now, no reports have shown temperature effects and other environmental variables on cephalopod mitochondria activity because of the lack of a method to evaluate mitochondrial respiratory parameters on those groups of species. In this sense and for the first time, this study developed a method to obtain mitochondrial respirometry data of adult Octopus maya’s heart. This protocol illustrates a step-by-step procedure to get high yield and functional mitochondria of cephalopod heart and procedure for determining the corresponding respiratory parameters. The isolation procedures described here require two hours, demonstrating that confident and replicable results can be obtained with this method.
Structural and Functional Composition of Humic Acids Isolated from Soils of Natural and Urbanized Territories of the European Far North and the Arctic
Authors:   Northern state medical University, Korelskaya Tatiana A.
Published: March 2022

The structural and functional composition of humic acids in natural and urbanized areas of the European Far North and the Arctic has been studied using modern physical and chemical research methods. It is shown that the content of fulvic acids for most of the studied soils is higher than humic acids; in soils, the process of humus formation is humate (replantozem, pelozem and humus-peat soil), humate-fulvate (turf soil, culturozem and urbanozem) and fulvate type (gleezem and lithozem); macromolecules of humic acids and himatomelanic acids of the studied soils are predominantly aliphatic in nature, with a high proportion of aromatic fragments, and FA have an aromatic structure. In addition, humus acids of natural soils located in more Northern regions are characterized by a high content of oxygen-containing functional groups compared to humus acids preparations of natural soils located to the South (turf and peat)
Solid Solutions in Aluminum Electrolytes with the Participation of LiF
Authors:   Institute of Chemistry and Chemical Technology FRC «Krasnoyarsk Scientific Center of the SB RAS», Zaitseva Yulia N.
Published: March 2022

The paper presents the investigation of the solid solutions formation in the fluoride system Na5Al3F14-Na3AlF6-K3AlF6 with the addition of LiF. Two local regions were under consideration. The first case concerns the possibility of potassium and sodium cations replacing with lithium in the elpasolite (K2NaAlF6) when LiF is added to the electrolyte. In the second, the effect of lithium fluoride on the chiolite (Na5Al3F14) was studied. The investigation was motivated by the need to control the composition of the electrolyte during the electrolytic production of aluminum. The electrolyte samples were obtained from the initial fluorides under laboratory conditions. Determination of crystal-chemical details of the structure of solid solutions was carried out by the method of full-profile analysis (Rietveld method) on multiphase polycrystalline samples. It was found that the addition of LiF in the structure of elpasolite is accompanied by a gradual substitution of lithium for sodium with the formation, ultimately, of the K2LiAlF6 phase with the lattice parameter a = 8.0779 Å. Potassium is not subject to substitution. No dissolution of LiF in the structure of cryolite (Na3AlF6) was found. It was shown that chiolite does not form solid solutions with LiF upon crystallization
A new record of chromosome count in mixoploid karyotype of Strobilanthes hamiltoniana (Steud.) Bosser & Heine (Acanthaceae)
Authors:   Cell and Molecular Biology Division, Department of Botany, University of Calicut, Chembrammal Reshmi , Thoppil John Ernest ,   Cell and Molecular Biology Division, Department of Botany, University of Calicut
Published: March 2022

The mixoploid karyotype found in the garden plant, Strobilanthes hamiltoniana, is a new record of chromosome count to the contemporary knowledge. The detailed karyomorphometrical analysis of the plant revealed a symmetric karyotype which is primitive. A hypoploid variant along with the normal chromosome complement was recorded within a root meristem with karyotype formulae as 10 nm and 20 nm respectively. In the diploid cells two pair of chromosomes have secondary constriction with an average chromosome length of 1.81 μm. The high values of symmetric indices and low values of asymmetric indices proved the primitive nature of the karyotype.
STUDY ON BUTTERFLY FAUNA OF KARANJA (GHADGE) TAHSIL OF DISTRICT WARDHA (MAHARASHTRA)
Authors: Wankhade Lokesh N
Published: March 2022

The fauna of butterfly species was studied from in and around area of Karanja (Ghadge) tahsil of Wardha District from period of July 2019 - June 2020. A total 41 species of butterflies belonging to 5 families were recorded. Maximum 18 species of butterflies were recorded from family Nymphalidae, followed by 10 species from family Lycaenidae, 7 species from family Pieridae and 3 species were recorded each from family Papilionidae and family Hesperiidae. In the above study 2 species of butterfly recorded comes under Wild Life Protection Act 1972 of India. The butterfly species Euchrysops cnejus comes under Schedule II and Euploea core comes under Schedule IV of the Indian Wild Life Protection Act 1972.
A clinical case of a hereditary form of colorectal cancer associated with a CHEK2 gene defect
Authors: Minniakhmetov Ildar R. , Bermisheva Marina A. , Kagirova Evelina M. , Gordiev Marat G. , Khusainova Rita I.
Published: March 2022

The article describes a clinical case of colorectal cancer with a positive family history. In the course of a molecular genetic study by NGS sequencing, a germinal c.1607delC mutation was detected in exon 15 of the CHEK2 gene (NM_007194.4). According to ClinVar, this option has uncertain clinical significance. The article provides literature data on cases of carriage of CHEK2 gene mutations. More careful monitoring of carriers of pathogenic variants in the CHEK2 gene from families with multiple manifestations of colorectal cancer is now recommended.
Redesign Of An HIV-1 Entry Inhibitor Core Region Influences Its Kinetic and Pharmacokinetic Properties
Authors:   , Karadsheh Rama , Bouchard Michael
Published: March 2022

The development of therapeutics for HIV-1 infection is necessary as drug-resistant viruses continue to emerge. The first and necessary step of infection is viral entry in which HIV-1 binds host cell receptors and fuses with the host cell membrane. This entry step is catalyzed by the envelope (Env) glycoprotein, which is an attractive yet underexploited therapeutic target in combination antiretroviral therapy (cART). A recent addition to the entry inhibitor class is Fostemsavir (brand name: Rukobia), which targets the gp120 subunit of Env and prevents viral attachment to the cell receptors. Fostemsavir is a pro-drug of BMS-626529/Temsavir that has addressed shortcomings of BMS-626529 with bioavailability and solubility. Prior to FDA approval of Fostemsavir, we explored bioisosteric replacement of BMS-626529 to identify novel lead compounds with enhanced solubility and pharmacokinetic properties. The piperazine core of BMS-626529 was replaced with other heterocyclic moieties to develop the SC series. Here, SC46 (azabicyclo[3.1.0]hexane core) and SC54 (dimethyl-piperazine core) were synthesized and assessed for antiviral activity and Env binding using surface plasmon resonance (SPR) kinetic analysis. These bioisosteres, in addition to previously published SC11, SC12, SC15, and SC28, were further characterized through in silico pharmacokinetic prediction analysis and metabolic stability assays. The SC bioisosteres displayed a range of potencies and retained their ability to interact with Env to different degrees. Replacement of the piperazine core to a flexible azetidine moiety in SC15 retained comparable binding affinity while replacement with a rigid azabicyclo[3.1.0]hexane moiety (SC28 and SC46) compromises the compounds affinity to a recombinant Env trimer, B41 SOSIP.664. Drug-likeness predictions in silico suggested that the bioisosteres were not more soluble than the parent BMS compound. It was also found that replacement of the piperazine core alters the stabilities of the compounds in human liver microsome assays. SC28 has more than twice the half-life than BMS-626529 and the lowest extraction ratio compared to the BMS compound and the other bioisosteres. We discovered that the orientation of SC28's core is critical for this increase in half-life. These analyses demonstrate that bioisosteric replacement is a rational method to create bioisosteres of a parent compound that retain biological activity but have altered kinetics and drug-like properties. Moreover, we have expanded our computational workflow to utilize in silico prediction of drug-like metrics and stability to further streamline lead hits in the discovery process of novel small-molecules that have anti-HIV-1 therapeutic potential.
Surgical approach to the treatment of patients with sequelae of intra-articular fractures of the distal tibia (literature review)
Authors:   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation, Kauts О.А. , Barabash Yu.A. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation, Kireev S.I. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation, Grazhdanov К.А. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation, Zuev P.P. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation, Kesov А.L. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation, Norkin I.А. ,   Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation
Published: March 2022

Background Management of patients with sequelae of intra-articular fractures of the distal tibia continues to be a substantial clinical challenge in orthopaedic trauma due to the high incidence, poor outcomes and high disability rate. The objective was to review Russian and international experience in repair of intra-articular ankle fractures and explore contemporary trends in treatment strategies. Material and methods The literature search was produced using medical electronic databases of eLibrary, PubMed, Medline, SpringerLink between 2000 and 2020 and keywords: cruzarthrosis, arthrodesis, total ankle arthroplasty, arthroscopy, distal tibia, ankle joint, joint replacement, intra-articular fractures of distal tibial. Results The article presents an insight into the problem of malunited and nonunited ankle fractures, ankle contractures and deformities, post-traumatic ankle arthritis. Major surgical techniques used to address sequelae of ankle fractures include correcting osteotomy, arthroscopy, distraction arthroplasty, arthrodesis, total ankle arthroplasty with the advantages and disadvantages with each of the practices. Discussion The surgical option would depend on the time of injury, condition of soft and bone tissue, malalignment and severity of ankle arthritis. Joint saving procedures of correcting osteotomy, arthroscopy or distraction arthroplasty can be applied at early stages of the disease, and arthrodesis or total ankle arthroplasty are secured for terminal stages of ankle arthritis. Benefits of total ankle arthroplasty include preservation and improvement of ankle mobility, a short inpatient period. Ankle fusion is associated with less complication rate and low costs. Conclusion There is an obvious need for a uniform treatment algorithm with specific indications and contraindications to each surgical option.
Injury to the distal tibiofibular syndesmosis, ways to improve treatment results (literature review)
Authors:   Clinic CJSC MCK, Moscow, Russian Federation, Nikiforov D.A. , Panin M.A. ,   Peoples’ Friendship University of Russia, Moscow, Russian Federation,   City Clinical Hospital No. 17, Moscow, Russian Federation, Protsko V.G. ,   Peoples’ Friendship University of Russia, Moscow, Russian Federation,   City Clinical Hospital No. 7, Moscow, Russian Federation, Borgut R.D. ,   Peoples’ Friendship University of Russia, Moscow, Russian Federation,   Clinical К + 31, Moscow, Russian Federation, Aliev R.N. ,   Peoples’ Friendship University of Russia, Moscow, Russian Federation,   City Clinical Hospital No. 31, Moscow, Russian Federation
Published: March 2022

Introduction Treatment of patients with distal tibiofibular syndesmosis (DTFS) ruptures remains controversial. Ankle fractures accompanied by syndesmosis rupture are associated with worse outcomes. There is no diagnosis and treatment algorithm for such injuries to date. The objective was to summarize the data on diagnosis and treatment of syndesmotic injury alone and in combination with ankle fractures through world literature review. Material and methods A systematic literature search was undertaken using elibrary, PubMed, ResearchGate databases with articles dated 1990 and later. The search depth was 30 years. With preliminary information collected low-relevant articles were excluded. Meta-analysis studies, randomized controlled trials, systematic reviews, cadaveric biomechanical studies were reviewed. Results Screws and suture buttons can be used to fix DTFS, and Volkmann, Shaput and Wagstaff fractures being transosseous injuries to DTFS can be repaired with osteosynthesis. Imaging evaluation of reduction can be produced with radiography, MSCT, MRI and arthroscopy. Partial injuries to the DTFS, if timely detected, can be treated conservatively with transition to surgical stabilization if signs of instability persist. Discussion Conventional radiography has very low diagnostic value for DTFS injury. Bilateral MSCT is recommended for assessment of a syndesmotic injury and MRI of the ankle joint is practical for partial isolated injuries. Concomitant injuries of the fibular notch of the tibia are recommended to address first prior to transsyndesmotic fixation. Open reduction of displaced DTFS is accompanied by a lower risk of fibular malposition and malreduction. Suture buttons are practical for transsyndesmotic fixation. Removal of positional screws does not affect the functional result of treatment. More stable osteosynthesis would be needed for DTFS injury in neuropathy.
Personalized approach to the treatment of patients with medial meniscus tear combined with varus deformity of the tibia
Authors:   N.N. Burdenko Main Military Clinical Hospital, Moscow, Russian Federation, Brizhan L.K. , Davydov D.V. ,   N.N. Burdenko Main Military Clinical Hospital, Moscow, Russian Federation, Kerimov А.А. ,   N.N. Burdenko Main Military Clinical Hospital, Moscow, Russian Federation, Tyulkevich B.V. ,   N.N. Burdenko Main Military Clinical Hospital, Moscow, Russian Federation, Nayda D.A. ,   N.N. Burdenko Main Military Clinical Hospital, Moscow, Russian Federation
Published: March 2022

Introduction Meniscus tear is one of the most common injuries of the knee joint. Medial meniscus tear accounts for 23–31 % of knee joint injuries. The main method of treatment is partial resection. As reported, 13.5 % of patients undergo arthroplasty within 15 years after meniscus resection, what is regarded as an unsatisfactory result. Purpose To evaluate and compare the long-term clinical, functional and radiological results of surgical treatment in patients with medial meniscus tear combined with varus deformity of the tibia and without it. Materials and methods From 2013 to 2020, medial meniscus tear was treated in 245 patients. The patients were divided into 4 groups. Group 1 included patients with a mechanical femorotibial angle (MFTА) from 0º to 3º who had arthroscopic meniscus resection (AMR). In the 2nd group, all patients also underwent AMR, but their MFTА was more than 3º. In group 3, patients with MFTА from 3º to 5º underwent simultaneous AMR and proximal fibular osteotomy (PFO) with the formation of a defect. Group 4 included patients with MFTА more than 5º, who underwent high tibial osteotomy (HTO) and AMR. Changes in the main lines and angles were assessed with telemetry radiography of the lower extremities. Functional results were evaluated before and after surgery using the Lysholm Knee Scoring Scale, 2000 IKDC, KOOS. Results Isolated meniscus resection in patients with MFTА more than 3º without axial correction leads to a gradual increase in the deformity by 1,070 ± 0.50º during the first year after surgery, and by 2.20 ± 0.70º to the fifth year. In groups 1, 3 and 4, there was no statistically significant increase in MFTА during the entire observation period. The clinical treatment results of patients of the four groups in the first three years after surgery did not differ statistically. However, within the period from 3 to 5 years, patients with MFTА greater than 3º who underwent only AMR had poorer clinical results than in the other groups (p < 0.001). Conclusions A personalized approach to the method of surgical treatment for medial meniscus tear based on the MFTА enables to correct the mechanical axis of the lower extremities and MFTА, and thus improve the long-term clinical, functional and radiological results of surgical treatment.
Surgical reconstruction for high-pressure injection injuries to the hand
Authors:   Research Institute – S.V. Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russian Federation, Aristov A.M. , Bogdanov S.B. ,   Kuban State Medical University, Krasnodar, Russian Federation,   Research Institute – S.V. Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russian Federation, Kurinniy S.N. ,   Research Institute – S.V. Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russian Federation, Karakulev A.V. ,   Kuban State Medical University, Krasnodar, Russian Federation,   Research Institute – S.V. Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russian Federation, Aladina V.A. ,   Kuban State Medical University, Krasnodar, Russian Federation,   Research Institute – S.V. Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russian Federation
Published: March 2022

Introduction High-pressure injection injuries to the hand result from injection of substances by high-pressure industrial devices. These are rare lesions with high risk of substantial long-term morbidity. Tissue defects resulting from staged debridement require skin grafting or vascularized island flap coverage. Hand therapy is an important part of the complex rehabilitation of such patients. The objective is to present complex surgical reconstruction of severe high-pressure injection injury of the hand aimed at preserving limb function. Material and methods Methods and results of surgical reconstruction of a patient with severe high-pressure injection injury of the hand treated at the Research Institute – S.V. Ochapovsky Regional Clinic Hospital No.1 in 2018–2019. Results Short-term result of surgical treatment demonstrated complete skin restoration and maximum possible preservation of underlying deep anatomical structures of the hand. Subsequent surgical interventions were aimed at restoring the hand function. Conclusion The restorative treatment of a high-pressure injection injury of the hand includes the earliest possible primary surgical treatment of the wound with wide revision, maximum removal of the injected substance and non-viable tissues and prevention of secondary injuries and infection in the wound. Nonfree vascularized flaps, full-thickness free grafts or split-skin autografts are used for skin reconstruction. Restoration of other functionally significant structures can be considered at a long term with wounds healed and autografts completely implanted. Hand therapy is integral to the comprehensive functional rehabilitation of the high-pressure injection injuries to the hand.
Developing the Interactive e-Module Based on Integrated Learning for Primary School Students
Authors:   Universitas Negeri Padang, Indonesia, Amini Risda , Usmeldi
Published: March 2022

In the 2013 curriculum subjects in primary schools were organized with themes, namely combining all subjects that reflect students’ everyday lives. However, the themes in the student’s book do not integrate one subject with the others and do not reflect the students real life. Therefore, it is hard for many primary school teachers in Padang to implement the integrated learning using the textbooks. This research aims to develop the interactive e-module based on the principles of integrated learning that can facilitate students in carrying out learning process, so it can improve students’ competency. The research and development of interactive e-module use four-D models that consist of four stages, namely define, design, develop and disseminate. The research subject was the interactive e-module based on integrated learning. The respondents of this research were 12 teachers and 70 Grade 5 students of three primary schools in Padang, West Sumatra, Indonesia. Data were collected using observation sheets, interview guides, questionnaires, and tests. There are three main results obtained from the research. First, according to expert judgment the interactive e-module is valid. Second, based on teacher and student's responses the module is very practical. Third, based on the student learning outcomes the interactive e-module is effective.
Discovering Sentiments and Latent Themes in the Views of Faculty Members towards the Shift from Conventional to Online Teaching Using VADER and Latent Dirichlet Allocation
Authors:   the Information Technology Department, Eastern Samar State University, Borongan City, Philippines, Casillano Niel Francis B.
Published: March 2022

This research primarily aimed at determining the frequently occurring words, the sentiment and the underlying latent themes in the responses of faculty members towards the shift from conventional to online teaching using data mining techniques. Orange data mining software was utilized to preprocess and analyze the data. VADER sentiment analysis and Latent Dirichlet Allocation Topic Modelling were used to generate the overall sentiment and the themes of the teachers’ responses. Results revealed that the most frequently occurring words in the responses of teachers were blended, online, students, teaching, teachers, learning, difficult, challenging, internet, and connectivity. Twenty-three (23) out of 37 (62%) responses were determined to have negative polarity making the general sentiment of faculty members towards the shift to online learning negative. The following themes were generated after the application of Latent Dirichlet Allocation Topic Modeling technique: unexpected shift from conventional to blended teaching, Mental and Physical Health Issues Related to the Implementation of Blended Learning, Online tools used in the conduct of Online Classes, Difficulties and Challenges in the Conduct of Blended/Online Learning, Slow Internet Connectivity as a Major Impediment in the Conduct of Online Teaching.
Development of Virtual Museum Model for Youth
Authors:   Srinakharinwirot University, Bangkok, Thailand, Klentien Unchana
Published: March 2022

The research provided guidance of the key elements on design and development of virtual museum which is a critical learning resource supporting learning experience outside the classroom for youth. The objective of this research is to develop a prototype of virtual museums for youth and evaluate the efficiency of the prototype. The research comprised three steps: 1) studying demands and expectations of virtual museums for youth by examining documents and researches about virtual museums, visiting 10 museums in Bangkok and 20 virtual museums in Thailand and worldwide, and conducting a questionnaire survey on 400 university students about their expectations of virtual museums; 2) developing a virtual museum website prototype and trialing it with three experts and 10 university students for improvement recommendation; and 3) having five experts evaluate the quality and efficiency of the improved prototype. The study showed that virtual museums for youth should consist of five key elements: 1) efficiency of website’s function, 2) the website itself, 3) type of media used in the virtual museum, 4) type of tools used in the virtual museum, and 5) evaluation of the virtual museum. The virtual museum prototype received a highest level score from the experts (mean = 4.56) and a high level score from the university students (mean = 4.43). Moreover, evaluation results from the other five experts showed that all elements of the improved prototype were appropriate.
Implementation of Information and Communication Technologies in the Process of Future Psychologists' Training in Consideration of Their Learning Motivation
Authors:   the Department of Political Psychology and International Relations, Faculty of Psychology, National Pedagogical Dragomanov University, 01601, Kyiv, Pyrogova str., 9, Ukraine, Tetiana Ponomarenko , Vsevolod Zelenin
Published: March 2022

This article covers the topicality of the implementation of information and communication technologies in the process of future psychologists' professional training. We have studied students’ attitude toward the implementation of educational new forms and established the type of students' learning motivation. The results of the empirical research have indicated that students consider it appropriate to implement online forms of learning in the educational process. We have found out that part-time students receiving the second education are more focused on mastering professional knowledge and skills, and there are students who are focused only on obtaining the higher education diploma among full-time students. We have identified five groups of obstacles that arise during the implementation of online learning forms in the educational process of students-psychologists and three groups of development resources that are necessary for the effective implementation of the educational process in the online format. Thus, we see the prospects for further research in the study of the level of digital competence development among the University teachers of psychological courses in higher education and their attitude toward the implementation of information and communication technologies in the educational process of future psychologists.
Vulval fibroadenoma, a common tumor at an uncommon site - A case report with review of literature
Authors: Malini Amritha , Hachem Fady , Ravindran Hiran
Published: March 2022

Vulval fibroadenoma is a rare benign tumour arising from anogenital mammary like glands. Vulva is an uncommon site for fibroadenoma. This is a case of 33 year old female presented with well defined mass in the right labia majora with a histopathological diagnosis of Vulval fibroadenoma confirming origin from ectopic breast tissue.
A Hybrid Genetic-Variable Neighborhood Algorithm for Optimization of Rice Seed Distribution Cost
Authors: Fadah Isti , Elliyana Anis , Auliya Yudha Alif , Baihaqi Yustri , Haidar Muhammad , Sefira Dhea Milinia
Published: March 2022

Companies engaged in agro-industry, such as rice seed companies, depend on an efficient distribution process because of the characteristics of rice seed products that are easily damaged and do not last long. The distribution and delivery of goods from the production plant to reach consumers must go through several local distributors in several areas (multi-level) such as distributor centers, retailers, and agents spread across several cities in East Java Province. Determining the distribution network will be more complex when a company produces more than one type of product (multiproduct). Based on previous research, the genetic algorithm (GA) has been proven to provide the best solution for various optimization and combinatorial problems. However, the application of classical GA has the drawback that it has not yet reached the optimum global point, so it needs to be hybridized using a variable neighborhood search (VNS) algorithm. VNS was chosen because it can find solutions globally and find solutions locally to cover the shortcomings of GA. Using hybridization of GA-VNS, the cost obtained is 32392960, as evidenced by the cost savings of 323190 compared to the classic GA of 32716150. GA-VNS takes relatively the same time as classic GA.
Heat Transfer and Flow Attributes of MHD Viscous Fluid Around a Circular Cylinder in Presence of Thermal Radiation
Authors: Kalita Bhrigu Kumar , Choudhury Rita
Published: March 2022

The crux of this paper is to explore heat distribution and motility traits of electrically conducting viscous fluid around a circular cylinder. The flow is two dimensional and is subjected to magnetic field and thermal radiation. Appropriate numeric computing environment is utilized for numerical solution of the set of transformed differential equations obtained using similarity transformation to the governing equations of the problem. The impinges of physical situation and different flow dictating parameters relevant to the problem have been depicted pictorially in the form of graphs. On the basis of these pictorial visualizations, attempts have been made for inferences regarding the problem. Point of separation is procured with respect to pertinent flow traits.