bluuebunny/crossref_metadata_2025 huggingface dataset:
Biological Therapy Survivability in Children with Psoriasis: Cohort Study
Authors: Ivanov Roman A. , Murashkin Nikolay N.
Published: November 2021

Background. There is a need to study genetically engineered biological therapy (GEBT) survivability and identify any significant risk factors for its ineffectiveness due to the increasing prevalence of psoriasis among children and the spreading GEBT administration. Such information has practical importance, it can be used to predict treatment outcomes and to develop individual therapeutic approaches.Objective. Our aim was to study biological therapy survivability and to identify risk factors for its ineffectiveness in children with moderate and severe forms of psoriasis.Methods. The study included data from 4-17 years old patients with moderate and severe forms of psoriasis vulgaris. Groups were formed according to the biological medication used. Statistical analyses were performed via SPSS Statistics. Biologic therapy survivability was determined via Kaplan-Meier method with the assessment of differences significance using log-rank test. Significant factors affecting cumulative risk growth were determined by Cox multiple regression method.Results. The study analysed data from the medical records of 105 patients. The average survivability of ustekinumab was 28.7 months, etanercept — 23.1, and adalimumab — 18.4. In the group of bio-naive patients, the survivability was higher: 30.8 months for ustekinumab and 24.4 months for ethanercept, while in the group of patients administrated previously with biological medication the survivability was 24.2 and 8.3 months, respectively. No statistically significant difference was revealed for adalimumab therapy. Significant risk factors for therapy ineffectiveness were the following: high body mass index (BMI) at the time of GEBT onset, aggravated family history, and prior use of one or several subsequent GEBT lines.Conclusion. The therapy survivability is inevitably declining over time. The best results were noted in bio-naive patients treated with ustekinumab that allows us to recommend it as the first-line drug in children with severe and moderate forms of psoriasis.
Un messaggio per i posteri. La tomba di Stanisław Miński nella Basilica di Sant’Antonio a Padova
Authors:   Uniwersytet Opolski, Lenart Mirosław
Published: November 2021

The article deals with the first burial in the tomb crypt built under the altar of the natio polona in the Basilica of St. Anthony in Padua. Stanisław Miński, a Polish state dignitary and diplomat who was passing through Padua on his way from Naples, was the one buried here. The tombstone, removed only in the first half of the 20th century, contained information about the laying of Miński’s body to rest in the place where church services associated with Poland and Poles were performed. For over three centuries, the tomb attracted the attention of pilgrims from Poland coming to Padua, reminding them not only of the outstanding Polish diplomat, but also of the natio polona, which, in the 16th and early-17th centuries, constituted a large and distinctive group of ultramontani, that is, those who came from beyond the mountains, most of whom had come to study at the flourishing university. In the article, little-known documents concerning the burial are gathered; these documents are kept in the Paduan archives and had been collected by the clergy and secular administration of the Basilica. Via the analysis of these documents, the cultural context in which the decision against bringing Miński’s body to Poland is reconstructed. The role of the institution, constituted by the administration of St. Anthony’s Basilica operating under the name of Veneranda Arca di Sant’Antonio, which grants permission to lay the body in the Basilica, is also established.
L’artista e i “luoghi della memoria”. Padova nelle illustrazioni di Aleksander Gierymski pubblicate sulla stampa
Authors:   Uniwersytet Wrocławski, Zarzycki Jakub
Published: November 2021

In the article, four illustrations by Aleksander Gierymski are described. These illustrations were completed for the illustrated press during Gierymski’s sojourn in Italy from 1885 to 1886. These illustrations were typical of the “Polish traces in Italy,” relating to Padua in this case, and were published in the magazines Wędrowiec and Kłosy. These illustrations show the tombs of exceptional Poles who were buried in Padua; commemorative plaques dedicated to them (in honour of Copernicus); or the monuments of Prato della Valle (Sobieski and Batory). However, in the article, based on the illustrations and the accompanying texts, and based on the artist’s correspondences (with the likes of Józef Ignacy Kraszewski, Michał Wiszniewski, Stanisław Dunin-Borkowski, and Władysław Bełza) and his diaries relating his time in Italy, the following issues, amongst others, will be addressed: Gierymski’s work method; the discourse (including the visual discourse) of “Polish traces in Italy” in Padua; Gierymski’s illustrations as an interpretation of the Polish lieux de mémoire in Italy. The article encourages an adoption, in the future, of a wider perspective that includes the illustrations of the “Polish traces in Italy” of other Polish artists from that period.
Quo vadis di Henryk Sienkiewicz nell’offerta delle case editrici italiane per l’infanzia e l’adolescenza
Authors:   Uniwersytet Wrocławski, Biernacka-Licznar Katarzyna
Published: November 2021

The paper outlines the publishing history of Henryk Sienkiewicz’s Quo Vadis in Italian editions for children and young adults in the 20th century. The research conducted so far has shown that Sienkiewicz’s novel was part of Italian publications for a young readership as early as at the beginning of the 20th century, and that the book was frequently republished and reedited by numerous publishing houses over the following decades. The paper aims to present the strategies applied by Italian publishers as they recast Sienkiewicz’s work into versions specifically targeting young readers. Sienkiewicz’s Roman narrative proved a source of easy revenue for many publishing houses. Discreditable translatory practices were, at least at the beginning of the 20th century, mainly the domain of Milanese publishers whose efforts also focused on reworkings of Quo Vadis for children and young adults after the Second World War. The paper discusses examples that vividly illustrate the commercialisation of literature and publishers’ responses to the changes of the Italian publishing market in the second half of the 20th century. The findings of a study that used quantitative methods to analyse the corpus of 18 Italian editions of Quo Vadis are presented as well.
Hereditary transthyretin-mediated amyloidosis with polyneuropathy: baseline anthropometric, demographic and disease characteristics of patients from a reference center
Authors: Sequeira Vanessa Cristina Cunha , Penetra Maria Alice , Duarte Lisa , Azevedo Fernanda Reis de , Sayegh Raphael Santa Rosa , Pedrosa Roberto Coury , Cruz Márcia Waddington
Published: November 2021

ABSTRACT Background: Hereditary transthyretin-mediated (hATTR) amyloidosis with polyneuropathy is a rare, inherited, multisystem, and often fatal disease caused by a variant in transthyretin (TTR) gene. Baseline characteristics of patients, especially anthropometric data, are scarce in the literature, and they are relevant to define effective treatment strategies. Objective: This study aimed to describe baseline demographic, anthropometric, and disease characteristics in a cohort of patients from a reference center in Brazil. Methods: Symptomatic patients not previously included in clinical trials and eligible for treatment were enrolled. Ethnicity, state of residence, age, sex, weight, height, body mass index (BMI), TTR variant, and Polyneuropathy Disability Score (PND) at diagnosis were analyzed. Results: Among the 108 patients enrolled, 58.33% were male, 60.19% were Caucasian, and 83.33% lived in the Southeast region. Mean age was 51.61 (±16.37) years, mean weight was 65.76 (±15.16) kg, mean height was 168.33 (±10.26) cm, and mean BMI was 23.11 (±4.45) kg/m2. The most prevalent variant was V30M (86.11%). Patients with PND score 0 presenting autonomic neuropathy were 14.81%. Patients with PND score I-II and III-IV were 52.78 and 32.41%, respectively. Mean weight and BMI were significantly lower in patients with sensory-motor manifestations. Conclusions: This is the largest cohort of patients in Brazil for whom anthropometric characteristics have been described. Baseline demographic, anthropometric, and disease data indicate that delay in diagnosis of hATTR amyloidosis with polyneuropathy is still a problem and that efforts must be made to expedite diagnosis and maximize opportunities for new disease-modifying treatments.
EEG education in Brazil: a national survey of adult neurology residents
Authors: Lourenço Elora Sampaio , Kowacs Dora Pedroso , Gavvala Jay Raman , Kowacs Pedro André , NASCIMENTO Fábio Augusto
Published: November 2021

ABSTRACT Background: In light of the established challenges of resident EEG education worldwide, we sought to better understand the current state of neurology resident EEG education in Brazil. Objective: To define Brazilian EEG practices including in-residency requirements for EEG training and competency. Methods: We assessed the perspectives of adult residents (PGY1-3) on EEG education and their level of confidence interpreting EEG with a 24-question online survey. Results: We analyzed 102 responses from 52 Brazilian neurology residency programs distributed in 14 states. There were 18 PGY1s, 45 PGY2s, and 39 PGY3s. Ninety-six percent of participants reported that learning how to read EEG during residency was very or extremely important. The most commonly reported barriers to EEG education were insufficient EEG exposure (70%) and ineffective didactics (46%). Residents believed that standard EEG lectures were the most efficient EEG teaching method followed by interpreting EEG with attendings’ supervision. Roughly half of residents (45%) reported not being able to read EEG even with supervision, and approximately 70% of all participants did not feel confident writing an EEG report independently. Conclusion: Despite the well-established residency EEG education requirements recommended by the Brazilian Academy of Neurology (ABN), there seems to be a significant lack of comfort interpreting EEG among Brazilian adult neurology residents. We encourage Brazilian neurology residency leadership to re-evaluate the current EEG education system in order to ensure that residency programs are following EEG education requirements and to assess whether EEG benchmarks require modifications.
Stability of early anterior open bite treatment: a 2-year follow-up randomized clinical trial
Authors: Dias Flaviana Alves , Oltramari Paula Vanessa Pedron , Almeida Marcio Rodrigues de , Conti Ana Claúdia de Castro Ferreira , Almeida Renato Rodrigues de , Fernandes Thais Maria Freire
Published: November 2021

Abstract This 2-year-follow up study compared and evaluated the stability of early anterior open bite (AOB) treatment based on different appliances. Children from 7 to 10 years with Angle Class I, AOB larger than 1.0 mm and fully erupted maxillary and mandibular permanent central incisors were eligible. The initial sample was 99 patients distributed, by simple randomization, into four groups: BS (bonded spurs), CC (chincup), FPC (fixed palatal crib) and RPC (removable palatal crib). Cephalometric analysis was performed at baseline (T1), final (T2) and 2-year post-treatment (T3) by taking the overbite measurements as the main outcome. Blinding was possible to cephalometric analysis. At T3, with dropouts, there were 63 individuals, being BS (n=15; overbite 0.19 mm; 11.54 years; 10 female (F)/5 male (M)); CC (n=11; overbite -0.19 mm; 11.41 years; 8 F/3 M); FPC (n=21; overbite 1.23 mm; 11.44 years; 15 F/6 M) and; RPC (n=16; overbite 0.73 mm; 11.67 years; 6 F/10 M). Changes in dentoskeletal variables and breaking deleterious oral habits during the follow up were statically analyzed with p<.05. Mandibular skeletal linear measurements and vertical dental components have gradually increased with age, manly at pubertal growth spurt and at the establishment of permanent dentition after treatment. Incisor teeth extrusion had impact on AOB correction and stability in 4 groups, which recorded a 1.15 mm-improvement of overbite after treatment (T3-T2). The experimental appliances were effective with stable results, being FPC the device recorded the highest AOB correction and the lowest patient withdrawal rate.
M1 and M2 macrophages phenotypes modulation after stimuli with materials used in endodontic treatment
Authors: Da Silva Raquel Assed Bezerra , Da Silva Léa Assed Bezerra , Gabriel-Junior Edson Alves , Sorgi Carlos Arterio , Faccioli Lúcia Helena , Massoni Vivian Vicentin , Nelson-Filho Paulo , Pucinelli Carolina Maschietto
Published: November 2021

Abstract The aim of this study was to evaluate the M1 and M2 macrophage modulation after stimuli with different materials used during endodontic treatment. In bone marrow-derived macrophage cell culture, from males C57BL/6 wild-type (WT) mice, gene expression analysis of markers to M1 and M2 macrophages was performed by qRT-PCR (Cxcl10, CxCL9, iNOS, Arg1, Chil3, Retnla and MRC1) and cytokine quantification by Luminex® (GM-CSF, IL-10, IL-6, IL-1β and TNF-α) after exposure to the five endodontic sealers: AH Plus, Sealapex Xpress, Endosequence BC Sealer, BioRoot RCS and a calcium hydroxide-based paste. For normal values, ANOVA test was used, followed by Tukey post-test. For non-normal values, the Kruskall-Wallis test was used. BioRootTM RCS and EndoSequence BC SealerTM stimulated the highest expression of markers for M1 macrophages, while calcium hydroxide-based paste stimulated the lowest expression of these gene markers. For M2 protein markers, BioRootTM RCS presented the highest stimulation while calcium hydroxide-based paste also presented the lowest stimulation. It was concluded that all the evaluated filling materials increased the genetic expression of pro- and anti-inflammatory markers: TNF-α and IL-10 respectively. The others proinflammatory mediators showed differences against the filling materials. However, this process did not induce the inflammatory response polarization, resulting in a hybrid macrophage.
Efficiency of a digital electrofulguration system in contaminated root canals in vitro
Authors: Silva Cimara B. B. , Bronzato Juliana D. , Herrera Daniel R. , Montagner Francisco , Nunes Elifas L. , Gomes Brenda P F A
Published: November 2021

Abstract Decontamination of the root canal (RC) system is essential for successful endodontic therapy. In this in vitro study, it was evaluated the disinfection potential of an electrofulguration device, the Endox® Endodontic System (EES), in RC infected with Enterococcus faecalis. Sixty-five human lower premolars were instrumented with MTwo® system. The specimens were distributed into six experimental groups (n = 10), according to the irrigation protocol: 2% chlorhexidine gel (CHX); CHX + EES; 5.25% sodium hypochlorite (NaOCl); NaOCl + EES; saline solution (SS); and SS + EES. Five specimens were untreated (control). RC samples were collected before (C1) and after EES treatment (C2), after chemo-mechanical preparation (CMP) (C3), and after final EES treatment (C4). All samples were plated for colony forming units (CFU/mL) onto solid media. The data were analyzed by Wilcoxon and Friedman tests for intragroup comparisons and by Kruskal Wallis test followed by Dunn’s test for intergroup comparisons (α = 0.05). Treatment with the EES did not significantly reduce the number of CFU/mL as compared to baseline levels (C1 vs. C2, p> 0.05). After CMP (C3), all groups showed a significantly reduced amount of CFU/mL (p <0.05), with no difference between CHX- and NaOCl-treated samples (p >0.05). Lastly, treatment with the EES following CMP (C4) did not significantly reduce the amount of CFU/mL (C3 vs. C4, p> 0.05). To conclude, the use of the Endox® Endodontic System did not result in considerable bacterial reduction at all operative times, while treatment with NaOCl and CHX was equally efficient for this purpose.
Fracture Resistance of Simulated Immature Teeth Reinforced with Different Mineral Aggregate-Based Materials
Authors: Pandolfo Mariana Travi , Rover Gabriela , Bortoluzzi Eduardo Antunes , Teixeira Cleonice da Silveira , Rossetto Hebert Luís , Fernades Paula Cristina dos Santos Vaz , Côrte-Real Inês Sansonetty Gonçalves , Carvalho Sandra Maria Fernandes , Garcia Lucas da Fonseca Roberti
Published: November 2021

Abstract This study assessed the fracture resistance of simulated immature teeth reinforced with calcium aluminate cement (CAC) or mineral trioxide aggregate (MTA) containing calcium carbonate nanoparticles (nano-CaCO3). The microstructural arrangement of the cements and their chemical constitution were also evaluated. Forty-eight canines simulating immature teeth were distributed into 6 groups (n=8): Negative control - no apical plug or root canal filling; CAC - apical plug with CAC; CAC/nano-CaCO3 - apical plug with CAC+5% nano-CaCO3; MTA - apical plug with MTA; MTA/nano-CaCO3 - apical plug with MTA+5% nano-CaCO3; and Positive control - root canal filling with MTA. The fracture resistance was evaluated in a universal testing machine. Samples of the cements were analyzed under Scanning Electron Microscope (SEM) to determine their microstructural arrangement. Chemical analysis of the cements was performed by Energy Dispersive X-ray Spectroscopy (EDS). The fracture resistance of CAC/nano-CaCO3 was significantly higher than the negative control (p<0.05). There was no significant difference among the other groups (p>0.05). Both cements had a more regular microstructure with the addition of nano-CaCO3. MTA samples had more calcium available in soluble forms than CAC. The addition of nano-CaCO3 to CAC increased the fracture resistance of teeth in comparison with the non-reinforced teeth. The microstructure of both cements containing nano-CaCO3 was similar, with a more homogeneous distribution of lamellar- and prismatic-shaped crystals. MTA had more calcium available in soluble forms than CAC.
Cytotoxicity and cytokine production by calcium silicate-based materials on periodontal ligament stem cells
Authors: Pedrosa Marlus da Silva , Alves Tomaz , Nogueira Fernando Neves , Holzhausen Marinella , Sipert Carla Renata
Published: November 2021

Abstract This study investigated the effect of three commercial calcium silicate-based materials (CSBM) on cytotoxicity and pro-and anti-inflammatory cytokines production in cultured human periodontal ligament stem cells (hPDLSCs). Culture of hPDLSCs was established and characterized. Extracts of Bio-C Sealer (Angelus, Londrina, PR, Brazil), MTA Fillapex (Angelus, Londrina, PR, Brazil) and PBS Cimmo HP (Cimmo Soluções em Saúde, Pouso Alegre, MG, Brazil) were prepared by placing cement specimens (5 x 3 mm) in culture medium. Then, the extracts were serially two-fold diluted (1, 1:2, 1:4, 1:8, 1:16) and inserted into the cell-seeded wells for 24, 48 and 72 h for MTT assays. TNF-α and IL-10 cytokines were quantified by ELISA at 24h-cell supernatants. Data were analyzed by ANOVA and Tukey’s test (α = 0.05). All CSBM exhibited some cytotoxicity that varied according to extract concentration and time of evaluation. MTA Fillapex presented the highest cytotoxic effects with significant reduction of metabolic activity/cell viability when compared to Bio-C Sealer and Cimmo HP®. TNF-α was significantly upregulated by the three tested cements (p < 0.05) while only MTA Fillapex significantly upregulated IL-10 in comparison to control. Taken collectively, the results showed that PBS Cimmo HP®, Bio-C Sealer and MTA Fillapex present mild and transient cytotoxicity and slightly induced TNF-α production. MTA Fillapex upregulated IL-10 release by hPDLSCs.
Physiological and sanitary quality of ryegrass seeds submitted to different defoliation frequencies
Authors: Cunha Ricardo Pereira da , Bonow Joice Fernanda Lübke , Mittelmann Andréa , Maia Manoel de Souza , Bohn Alberto , Oliveira Roberto Caetano de , Silva Jéssica Dias Gomes da , Pedroso Carlos Eduardo da Silva
Published: November 2021

ABSTRACT: This study determined the effect of different defoliation frequencies in a long-cycle ryegrass cultivar on yield components and the physiological and sanitary quality of seeds. Four defoliation frequencies were applied (without, one, two, and three defoliations). The time between defoliations was 350 degree-days. At the first, second, and third defoliation time, the plants were 15 cm, 20 cm, and 35 cm, respectively, and were lowered to half their height. The yield components and plant structure were evaluated through the tillers, along with the physiological quality of the seeds, which was verified by germination tests, first germination count, accelerated aging, tetrazolium test, field emergence, and weight of a thousand seeds. For the sanitary quality analysis, the percentage (%) of fungi incidence in the seeds was verified. The second defoliation determined the seeds’ high physiological and sanitary quality due to the higher amount of primary and secondary tillers produced concerning the other treatments. However, there was no significant difference for the third defoliation since the aerial tillers issued the same quality of seeds originated from primary and secondary tillers. The average incidence of fungi such as Colletotrichum sp., Fusarium sp., Phoma sp., and Dreshslera spp. was lower in ryegrass plants subjected to three defoliations.
Physical therapy modalities in the rehabilitation of cats (Felis catus) with neurological and orthopedic conditions
Authors: Colvero Ana Caroline Teixeira , Schwab Marcelo Luís , Ferrarin Dênis Antonio , Ripplinger Angel , Wrzesinski Mathias Reginatto , Rauber Júlia da Silva , Beckmann Diego Vilibaldo , Mazzanti Alexandre
Published: November 2021

ABSTRACT: This retrospective study described the therapeutic modalities used for the rehabilitation of cats with neurological and orthopedic diseases and provided data regarding the number of sessions, frequency, and treatment duration; the study also evaluated the modality acceptance by this species. Twenty cats were selected, 11 with neurological diseases and nine with orthopedic conditions. Acute spinal cord trauma and femoral fracture were the most frequently observed neurological (72.7%) and orthopedic (44.4%) conditions, respectively. Manual therapies comprised of passive stretching (PS), passive range of motion (PROM), and bicycle movement (BM) exercises were included in all the protocols.Therapeutic modality acceptance was positive for physical agents, thermotherapy, and hydrotherapy (100%);in manual therapies, it was positive in 40% and partially positive in 60% of cats; in kinesiotherapy, it was positive for all the assisted active exercises and negative for the active exercises. The number of physical therapy sessions significantly influenced the positive acceptance of PS (P < 0.05). The PS, PROM, and BM exercises were the most commonly used modalities; the number of physiotherapy sessions and duration of treatment were higher in cats with neurological diseases, and acceptance was positive in most therapeutic modalities.
Preliminary mechanical evaluation of two novel veterinary angle-stable-threaded interlocking nail systems
Authors: Nóbrega Jordana da Costa , Lucena Dayvid Vianêis Farias de , Minto Bruno Watanabe , Dias Luis Gustavo Gosuen Gonçalves
Published: November 2021

ABSTRACT: The interlocking nail represents an excellent option as a surgical approach to treat fractures in long bones in veterinary medicine. However, failures were reported mainly due to a slack present in the interface of the rod with the screws. The present study tested and mechanically compare axial compression loads of two novel models of stable angle interlocking nails with threaded holes. Among the two models, one was uniplanar and the other was multiplanar with orthogonally arranged distal holes. Twenty-one specimens made of polylactic acid were used for the implantation of interlocking nail´s rods, divided into three groups: conventional interlocking nail (G1), novel interlocking nail with a stable angle with holes arranged in a single plane (G2), and novel interlocking nail with a stable angle in two planes, with the penultimate hole at 90 degrees from the others (G3). Biomechanical tests were performed using axial, cyclic, and destructive compression load for comparison between them. All the specimens showed plastic deformation in the screws after destructive tests, in both proximal and distal sides, being highly intense in G1. G2 and G3 of the stable angle rods supported higher loads than G1 in all tests performed (P<0.05). The novel stems did not differ statistically from each other (P>0.05). The initial hypothesis that the novel models would provide increased stability was confirmed; however, no differences were demonstrated between them. The screw locking system on the rods allowed high resistance values in the tests performed, proving to be effective and potentially applicable in real clinical situations.
Dating violence among adolescents from a region of high social vulnerability
Authors: Oliveira Ana Paula França de , Silva Silvia Mara Carvalho , Campeiz Ana Beatriz , Oliveira Wanderlei Abadio de , Silva Marta Angelica Iossi , Carlos Diene Monique
Published: November 2021

Objective: to know and analyze the perceptions of adolescents with high social vulnerability regarding the establishment of dating violence. Method: a qualitative research study carried out with 19 adolescents from a central municipality São Paulo, Brazil. Data collection took place by means of focus groups and field diaries, with the data being analyzed thematically. Results: two categories emerged: “A new female posture in a context of traditional gender norms” and “Violence in intimate relationships: the (non)perception of adolescents”. Traditional gender norms still occupy a significant place in the design of dating violence among adolescents. Such behaviors are more visible in these relationships, when commitment and exclusivity are seen as the main characteristics, authorizing possession and control. Jealousy emerges as the main trigger for violence and the technologies appear as contemporary resources to reinforce it. Conclusion: the need for early interventions with adolescents is reiterated, with a focus on actions that promote gender equality.
Mathematical models to describe the growth curves of Vietnamese Ri chicken
Authors: Nguyen T. H. , Nguyen C. X. , Luu M. Q. , Nguyen A. T. , Bui D. H. , Pham D. K. , Do D. N.
Published: November 2021

Abstract Ri chicken is the most popular backyard chicken breed in Vietnam, but little is known about the growth curve of this breed. This study compared the performances of models with three parameters (Gompertz, Brody, and Logistic) and models containing four parameters (Richards, Bridges, and Janoschek) for describing the growth of Ri chicken. The bodyweight of Ri chicken was recorded weekly from week 1 to week 19. Growth models were fitted using minpack.lm package in R software and Akaike’s information criterion (AIC), Bayesian information criterion (BIC), and root mean square error (RMSE) were used for model comparison. Based on these criteria, the models having four parameters showed better performance than the ones with three parameters, and the Richards model was the best one for males and females. The lowest and highest value of asymmetric weights (α) were obtained by Bridges and Brody models for each of sexes, respectively. Age and weight estimated by the Richard model were 8.46 and 7.51 weeks and 696.88 and 487.58 g for males and for females, respectively. Differences in the growth curves were observed between males and female chicken. Overall, the results suggested using the Richards model for describing the growth curve of Ri chickens. Further studies on the genetics and genomics of the obtained growth parameters are required before using them for the genetic improvement of Ri chickens.
Performance evaluation of the commercial aquafeeds available in the market of Pakistan on Channa marulius (Sole)
Authors: Farid M. , Khan N. , Fatima M. , Rasool F. , Azmat H. , Iqbal K. J. , Nazir S. , Bano S. , Khizar A. , Asghar M.
Published: November 2021

Abstract The present study aimed to determine the effect of different levels of protein on the growth, body composition, amino acid profile and serology of Channa marulius fingerlings. The experiment was conducted in ten happas installed in earthen ponds, each stocked with 10 fishes for 90 days. Four commercial fish feeds having 25%, 30%, 32% and 40% crude protein (CP) levels were fed to fish at 3% of their wet body weight three times a day. The results of the study revealed that highest weight gain, feed conversion ratio and survival rate were observed in 30% protein feed. Meanwhile, moisture content was higher in fish fed with 30% CP feed while highest crude protein was recorded in 40% CP fed fish. Lowest fat content was observed in 32% CP feed. Amino acid profile of fish revealed better results in 30% CP feed. Total protein, glucose and globulin were also highest in fish feeding 30% CP feed, while albumin was highest in 40% CP feed. It is concluded that 30% CP feed showed better results in terms of growth, amino acid profile and serological parameters without effecting fish body composition.
Insects and spiders on Acacia mangium (Fabaceae) saplings as bioindicators for the recovery of tropical degraded areas
Authors: Lima J. S. , Leite G. L. D. , Guanabens P. F. S. , Soares M. A. , Silva J. L. , Mota M. V. S. , Lemes P. G. , Zanuncio J. C.
Published: November 2021

Abstract Acacia mangium is a pioneer species with fast growth and frequently used in the recovery of degraded areas. The objectives were to evaluate insects and spiders, their ecological indices and interactions on A. mangium saplings in a tropical degraded area in recovering process. The experimental design was completely randomized with 24 replications, with treatments represented by the first and second years after A. mangium seedling planted. Numbers of leaves/branch, branches/sapling, and ground cover by A. mangium saplings, Hemiptera: Phenacoccus sp. and Pachycoris torridus; Hymenoptera: Tetragonisca angustula and Trigona spinipes, Brachymyrmex sp., Camponotus sp. and Cephalotes sp.; Blattodea: Nasutitermes sp. and Neuroptera: Chrysoperla sp.; abundance, species richness of pollinating insects, tending ants, and the abundance of Sternorrhyncha predators were greatest in the second year after planting. Numbers of Hemiptera: Aethalium reticulatum, Hymenoptera: Camponotus sp., Cephalotes sp., Polybia sp., T. angustula, T. spinipes, tending ants, pollinating insects, Sternorrhyncha predators and species richness of tending ants were highest on A. mangium saplings with greatest numbers of leaves or branches. The increase in the population of arthropods with ground cover by A. mangium saplings age increase indicates the positive impact by this plant on the recovery process of degraded areas.
¿A dónde vamos? Condiciones socioeconómicas y las modalidades frecuentadas por los hogares colombianos para la compra de alimentos
Authors: Torres-Pabon Giselle
Published: November 2021

Resumen: El objetivo de este artículo es analizar la relación entre condiciones socioeconómicas de los hogares colombianos y los lugares que estos frecuentan para la obtención de alimentos, durante el periodo 1993-2014. La pregunta para responder es: ¿cómo las condiciones socioeconómicas de los hogares se asocian con los usos de una modalidad de abastecimiento de alimentos en Colombia en dicho periodo? Se utiliza la Encuesta Nacional de Calidad de Vida, realizada por el Departamento Nacional de Estadística colombiano para los años 1993, 1997, 2010 y 2014. La metodología que se sigue es cuantitativa. Los resultados se dividen en dos partes. La primera presenta un análisis descriptivo; y la segunda expone los resultados de la estimación de un modelo multinomial, donde la variable dependiente son las modalidades que utilizan los hogares para el abastecimiento de alimentos (1. Comercial, 2. No comercial y 3. Ambas modalidades). Las variables independientes corresponden a las características socioeconómicas de los hogares: cantidad de mujeres, cantidad de personas, nivel educativo, sector (Urbano/Rural). Los resultados demuestran un incremento en el uso de las modalidades comerciales en el periodo de análisis y revelan vulnerabilidad alimentaria para diferentes grupos de la sociedad colombiana, especialmente para la mujer colombiana.
Caracterização da logística de distribuição de frutas, legumes e verduras na Central de Abastecimento de Campinas/SP
Authors: Aliotte Joseane Thereza Bigaran , Filassi Monique , Oliveira Andréa Leda Ramos de
Published: November 2021

Resumo: A redução das perdas e dos desperdícios de frutas, legumes e verduras (FLV) contribui para o aumento da oferta de alimentos. A identificação das perdas ao longo da cadeia logística de FLV possibilita a proposição de ações mitigadoras. O objetivo desta pesquisa é caracterizar as práticas operacionais da logística de distribuição das principais FLV comercializadas pela Central de Abastecimento (CEASA) de Campinas. A metodologia é dividida em duas partes: a primeira trata da estruturação do problema pela abordagem sistêmica por meio das técnicas conhecidas como gráfico Behavior Over Time (BOT) e modelo de loop causal, que subsidiam a segunda etapa com a aplicação de questionários aos comerciantes atacadistas para descrever as operações logísticas, validar os resultados encontrados na estruturação do problema e propor estratégias para a redução das perdas na comercialização. Os resultados indicaram que práticas ineficientes, como falta de transporte refrigerado, embalagens não adequadas, falta de rastreabilidade e manuseio excessivo, estão associadas às perdas. Conclui-se que a adoção do transporte refrigerado para manter a cadeia logística do frio é o diferencial para uma maior preservação da qualidade das FLV, além do uso de novas tecnologias de embalagem e treinamentos para os agentes da cadeia quanto às boas práticas pós-colheita.
Prontuário Eletrônico do Paciente na educação médica: percepções de docentes e preceptores
Authors: Rangel Ana Maria Pereira , Struchiner Miriam , Salles Gil Fernando
Published: November 2021

Resumo: Introdução: A implantação do Prontuário Eletrônico do Paciente (PEP) em unidades hospitalares de ensino tem proporcionado a integração do uso de tecnologia de informação em saúde (TIS) na educação médica e na prática clínica. Objetivo: Este estudo analisou a percepção de professores e preceptores-médicos, de uma universidade pública, sobre a integração do uso do PEP nas atividades práticas curriculares. Método: Trata-se de um estudo de abordagem qualitativa. A coleta de dados foi realizada por meio de entrevistas semiestruturadas com seis professores e quatro preceptores de um curso de Medicina. O estudo adotou como categorias de análise os domínios de competências e os resultados de aprendizagem com o uso do PEP, identificados e aprimorados por um estudo multicêntrico inglês: saúde digital, acesso e geração de dados, comunicação, trabalho multiprofissional e acompanhamento e monitoramento. Adotou-se ainda a categoria “questões pedagógicas” para estimular a reflexão dos sujeitos da pesquisa sobre suas práticas pedagógicas com o PEP. Para análise dos dados, utilizou-se análise temática de conteúdo. Resultado: O estudo apontou que os professores e preceptores identificaram a necessidade de orientação formal para que os discentes utilizem TIS no seu desenvolvimento educacional e profissional, na preservação do sigilo e da confidencialidade das informações, e no atendimento ao paciente. Para os sujeitos da pesquisa, o uso de sistemas de suporte à decisão associados ao PEP contribui para o processo de ensino-aprendizagem, além de possibilitar maior visibilidade das informações dos demais profissionais de saúde e o acompanhamento da história clínica dos pacientes pelos discentes. O PEP é uma ferramenta assistencial que tem potencial para promover o uso de metodologias ativas, pois contextualiza o ensino, permite autonomia e autoria aos discentes e os instiga na busca por conhecimento. Conclusão: A integração curricular de TIS tem sido apontada como um caminho para o desenvolvimento de competências e habilidades clínicas dos discentes, quando estiverem utilizando o PEP nas unidades de prática clínica.
Systemic conditions of diabetic patients diagnosed with apical periodontitis
Authors: SILVA Poliana Amanda Oliveira , LIMA Stella Maris de Freitas , ALMEIDA Jeeser Alves de , GRISI Daniela Corrêa , KOGAWA Evelyn Mikaela , LONGATTI Simone Cruz , FRANCO Octávio Luiz , REZENDE Taia Maria Berto
Published: November 2021

ABSTRACT Objective: This study aimed to evaluate the association between glycemic control status in type 2 diabetes mellitus (T2DM) patients and apical periodontitis. Methods: Twenty-seven patients were involved in this study. The survey was based on anamnesis, intra and extra oral examination and radiographic evaluation. Diabetes mellitus information involved type of diabetes and blood glucose analysis. Patients were divided according to their metabolic control status (glycemic controlled and poorly controlled T2DM patients). Results: A higher fasting blood glucose level (p = 0.004) and a higher percentage of HbA1c (p = 0.0001) were demonstrated in poorly controlled T2DM patients when compared to glycemic controlled T2DM. However, the frequency of apical periodontitis and the elapsed time since diabetes mellitus diagnosis were higher in controlled T2DM patients, reaching 64%. Nevertheless, controlled T2DM patients presented a higher number of apical periodontitis cases (p < 0.05). Findings support that controlled patients T2DM presented higher presence of apical periodontitis than poorly controlled T2DM ones. In these patients, the time elapsed since the diagnosis was higher, which may have provided a longer period of oscillation and/or uncontrolled metabolism. Conclusions: Therefore, it might contribute to the development and maintenance of apical periodontitis in glycemic controlled patients of this study.
Dolphin software accuracy in soft tissue facial profile prediction of Class II patients in orthognathic surgery
Authors: JODAS Claudio Roberto Pacheco , TEIXEIRA Rubens Gonçalves , LEAL Marilia de Oliveira Coelho Dutra , COSTA Sarah Teixeira , ZANFORLIN JUNIOR Wanderley , NOUER Paulo Roberto Aranha
Published: November 2021

ABSTRACT Objective: The present study aimed to analyze the accuracy of the Dolphin Imaging 11.9® computer program in the surgical prediction of the soft tissue facial profile. Methods: The investigators designed and implemented a retrospective study. It was used a sample of 55 patients, being 14 males and 41 females, aged from 19 to 55 years old. All patients were subjected to surgery orthognathic bimaxillary combined with mentoplasty, in Class II facial profile – Angle. Patients’ actual results were compared to the obtained up to a year and a half after the surgery procedure. The study was delineated in three phases. In the first phase, cephalometric preoperative radiographs were performed; in the second phase the postoperative cephalometries were made; in the third phase, the measurements of the soft profile of the virtual analysis were compared with the real post-surgical profile. The data was collected and subjected to statistical analysis in the “R” program, using the t test and ANOVA. Results: The results demonstrated that measures A’ and Eis were underestimated in -0.15 ± 0. 52 mm and -0.47 ± 1.05 mm, respectively, while measures Pg’ and ANL were overestimated at 0.76 ± 1.98 mm and 3.31 ± 3.60° respectively. There was no evidence of measures, Ls, Li and B’, being different between real and virtual. Conclusions: The results of this study suggest that Dolphin 11.9® computer program complies with the function of preserving with reliability virtual surgical planning.
Masticatory efficiency, quality of life, comfort, retention and satisfaction on digital denture: case report
Authors: CARREIRO Adriana da Fonte Porto , CARDOSO Rachel Gomes , TÔRRES Ana Clara Soares Paiva , LIRA Andréa Fabiana , MELO Laércio Almeida de , COOPER Valerie
Published: November 2021

ABSTRACT The aim of this study was to describe a clinical protocol for fabrication of maxillary and mandibular dentures using CAD/CAM technology. Further, digital and conventional dentures fabricated for the same patient were compared. The comparison was based on patient’s satisfaction, comfort, retention, number of follow-up sessions, masticatory performance and quality of life. No laboratorial step was needed for CAD/CAM fabrication and less sessions were required up to denture insertion. Compared to the conventional dentures, digital dentures provided better satisfaction, comfort and retention and required less follow-up sessions. Both dentures presented similar results about masticatory performance and quality of life. As a conclusion, digital denture is a viable treatment alternative for edentulous patients. However, controlled and randomized clinical trials are required to reveal the real benefits of this treatment alternative compared to the conventional denture.
Screwed and cement implant prosthesis: current clinical considerations
Authors: COSTA Bruna Palmeira , FREIRE Julliana Cariry Palhano , MELO Waleska Ohana de Souza , FIGUEIRÊDO JÚNIOR Ernani Canuto , RIBEIRO Eduardo Dias , PEREIRA Jozinete Vieira
Published: November 2021

ABSTRACT Introduction: There is no consensus as to which cemented or screwed retention system is best to avoid bone loss around the implant from a fixed implant-supported restoration. Objective: To evaluate the prosthesis retention systems on screw and cemented implants, regarding: bone loss, survival and failure rate, biological complications and microbiological analysis. Methods: A search was made for scientific articles that contemplated the subject through the databases Pubmed and SciELO, without period restriction. The titles, abstracts and then access to the full text has been verified. Results: It was found that excess cement may play an important role in the development of peri-implant disease. Technical failures are most seen in prosthesis retained by screws, and biological complications in cemented crowns. The success rate for both restraint systems is high, and retention-independent implant prosthesis treatment provides predictability. Conclusion: The appropriate retention system for the patient depends on several factors, including indication, advantages and disadvantages, retention provided, aesthetics and clinical performance.
Dental surgical care in blood dyscrasias patients: an epidemiological study
Authors: CESCONETTO Lorenzzo De Angeli , TORRES Luiz Henrique Soares , CANÇADO Renata Pittella , PUPPIN André Alberto Camara
Published: November 2021

ABSTRACT Introduction: In Brazil, about 18.500 people have some kind of hereditary coagulopathy. In combination, the increase in life expectancy has led to an increasingly frequent presence of older people in medical offices. These patients make use of many drugs, including those that produce anticoagulant effects. The dentist should be aware about the impact of bleeding disorders during the approach of their patients, especially if invasive procedures are considered. Objective: To identify the most prevalent blood dyscrasias presented by patients covered by the Program of dental surgical care to patients with blood dyscrasias; to establish the presence of associated diseases and investigate the correlation between pre- and postoperative drug protocols and the occurrence of postoperative complications. Methods: This was an epidemiological retrospective cross-sectional study of medical reports used by the program. After the survey of defined variables, data were tabulated in Microsoft Excel ® software and evaluated using the chi-square and Fisher’s exact tests. Results: One patient was identified as having Human Immunodeficiency Virus and 18 with Hepatitis C virus. There was a statistically significant difference between patients with haemophilia B and Hepatitis C. The administration of tranexamic acid as pre- and post-surgical protocol was the therapy of choice. Of the 11 patients with vWD, 7 of them received tranexamic acid as preoperative medication. Conclusion: The appropriate retention system for the patient depends on several factors, including indication, advantages and disadvantages, retention provided, aesthetics and clinical performance.
Active role of flower shops in the commercialization of roses
Authors: Orozco Nereida Rodríguez , Anastasio Emmanuel Vázquez , Gabriel Ariadna Linares , Chontal Mario Alejandro Hernández
Published: November 2021

Abstract Retail florist activities are essential elements in the rose (Rosa spp.) market since they generate significant income and employment. In these jobs, florists gain recognition by their designs that captivate consumers. At the same time, they are key entrepreneurs in the commercialization of roses. Then, the objective of the research was to know the entrepreneurial role of florists in the commercialization of roses (Rosa spp.) in southern Veracruz, Mexico. An exploratory research was conducted in flower shops, five in Coatzacoalcos, nine in Minatitlán and six in Acayucan. Interviews were conducted with florists (n = 20). The categories of analysis used were the demographic, psychosocial and sociocultural profile of the florists as innovative entrepreneurs. In regards to the demographic profile, these economic agents have the experience and knowledge necessary to develop their activity. In short, florists are identified as family micro-enterprises with establishments that are 20 years old. In the psychosocial profile, florists present low innovative capacity with respect to the composition of their floral arrangements; however, they are characterized as risk takers with the ability to solve problems. Finally, the sociocultural profile demonstrates the florists-intermediary-producers collaboration; such entrepreneurial activity generates economic incentives with local-regional influence. Therefore, florists need to strengthen their links with other florists, producers and distributors to improve their innovative capabilities that will benefit both themselves and consumers.
Micropropagation and assessment of somaclonal variation in Galanthus transcaucasicus in vitro plantlets
Authors: Asadi Narges , Zarei Hossein , Hashemi-Petroudi Seyyed Hamidreza , Mousavizadeh Seyyed Javad
Published: November 2021

Abstract In vitro culture of twin-scaling explants of Galanthus transcaucasicus with different concentrations of plant growth regulators (PGRs) including 0.5, 1, 2, 3, 4, 6, 8, and 10 mg L-1 naphthaleneacetic acid (NAA) and 0.5, 1, 2, 3, and 4 mg L-1 benzyladenine (BA) was studied. After 18 weeks, the number of regenerated bulblets and intensity of callus was measured. Subsequently, bulblets were transferred to a medium with 0.5, 1, 2, 3, and 4 mg L-1 NAA and 0.5, 1, 2, 3, and 4 mg L-1 BA and, after 15 weeks, the bulblets length and diameter were measured. The highest intensity of callus was obtained on 4 mg L-1 NAA or 8 mg L-1 NAA with 1 mg L-1 BA. The highest number of regenerated bulblets was detected with 6 mg L-1 NAA and 2 mg L-1 BA. The highest diameter of bulblets occurred on four mgL-1 NAA (9.4 mm), while the lowest was observed on 0.5 mg L-1 BA (1.83 mm). The analysis of genetic variation using ISSR revealed that there was no somaclonal variation among the regenerated plants from BA and low level of NAA, but there was a significant somaclonal variation at high concentrations of NAA.