bluuebunny/crossref_metadata_2025 huggingface dataset:
Plagiarism Detection Application for Computer Science Student Theses Using Cosine Similarity and Rabin-Karp
Authors: Ansyari Taufik Habib , Abdullah Dahlan , Rosnita Lidya
Published: December 2024

Plagiarism detection is critical in maintaining academic integrity, particularly in higher education. This study focuses on developing a plagiarism detection application for Computer Science student theses. The application leverages the Cosine Similarity and Rabin-Karp algorithms to accurately and efficiently detect textual similarities. Developed using JavaScript, the application provides an intuitive interface and reliable performance, making it a practical tool for educational institutions. The application includes features allowing users to upload thesis documents, analyze textual content, and measure plagiarism levels by comparing them to an existing dataset. The Cosine Similarity algorithm measures the overall similarity between documents, while the Rabin-Karp algorithm focuses on identifying exact matches in phrases and sentences. The results demonstrate the efficacy of both algorithms. For titles, the Cosine Similarity algorithm achieved a 100% similarity rate for identical documents while detecting minor plagiarism with a similarity level of 5.86% for other documents. For abstracts, it achieved 100% similarity for the first document, 2.78% for the second document, and 8.37% for the third document. These findings highlight the algorithm's ability to detect exact matches and partial overlaps in textual content. The Rabin-Karp algorithm showed comparable performance, particularly in detecting phrase-level similarities. For titles, it recorded 100% similarity for identical documents, 11.42% for the second document, and 16.92% for the third document. For abstracts, the algorithm also achieved 100% similarity for the first document, 11.42% for the second document, and 16.81% for the third document. The study confirms that both algorithms complement each other in detecting different forms of plagiarism. The Cosine Similarity algorithm excels in identifying global patterns of similarity, while the Rabin-Karp algorithm is more suited for finding exact matches in specific phrases or sentences. This dual approach provides a comprehensive solution for detecting plagiarism in academic theses. The findings from this research are promising and highlight the potential of the application as a reliable tool for ensuring academic integrity. Future improvements could include expanding the dataset, enhancing the user interface, and integrating additional algorithms for cross-language plagiarism detection. This application contributes to academic honesty and is a valuable resource for educators, researchers, and students in combating plagiarism effectively.
Learning of McDonald’s Operation Management & Consumer Behavior Analysis: A Qualitative Study
Authors: Nawangwulan Irma M , Anantadjaya Samuel PD , Agus Rachmat Timotius
Published: December 2024

This paper will discuss the overall operation management and the typical characteristics or behaviours of McDonald's consumers. The aim is to demonstrate McDonald's ability to comprehend the diverse facets of consumer purchasing behaviour and effectively manage its operations to address all potential challenges. The research method in this paper uses a descriptive qualitative approach. McDonald's is a globally recognised company in the fast-food industry. The operational strategy of McDonald's is to cut costs, boost product quality, guarantee timely delivery to consumers, and innovate continuously to improve performance. Fast food giant McDonald's can keep expenses down because of careful management. McDonald's never compromises on the quality of its food or service to its consumers. Fast food giant McDonald's uses a just-in-time system to meet customer demands for quick service and high-quality food on the go. Marketing and advertising widely employ the AIDA model to delineate the stages of consumer buying decisions and elucidate how advertisements engage and involve consumers in purchasing. McDonald's advertising employs the AIDA model to draw in consumers and create captivating ads that consistently attract new customers. Examining McDonald's marketing pillars is fascinating, as they are a key indicator of global success. McDonald's has developed a formula of four key elements that effectively maintain a business, set clear objectives, and effectively communicate with its customers.
The Effect of Carbon Nanotubes on the Marshall Characteristics of AC-WC Asphalt Mixture
Authors: Akbar Said Jalalul , Maizuar Maizuar , Muthmainnah Muthmainnah , Ersa Nanda Savira , Desmi Adzuha , Arfiandi Joni , Adha Ridwan , Larasati Putri Ditya
Published: December 2024

Carbon Nanotubes (CNTs) are cylindrical nanostructures with exceptional mechanical strength, high electrical conductivity, and excellent heat transfer capabilities, making them a promising additive in asphalt mixtures. This study investigates the effect of CNTs on the Marshall parameters of Asphalt Concrete-Wearing Course (AC-WC) mixtures using 60/70 penetration asphalt. CNTs were added to asphalt at 60°C, followed by coarse and fine aggregates preheated to 150°C. Marshall parameter tests were conducted on the samples, and the results showed a significant increase in stability compared to conventional asphalt. Asphalt stability increased by 9%, with the highest value obtained at a CNT concentration of 0.015%, reaching 2177.83 kg. The optimal stability was achieved at a CNT concentration of 0.015%. This study demonstrates that CNTs can be effectively utilized to enhance the performance of AC-WC asphalt mixtures. The flow values decreased as the CNT content increased because CNTs make the asphalt mixture stiffer, improving temperature resistance.
Skrócenie tygodniowego wymiaru czasu pracy w Polsce na tle wybranych rozwiązań europejskich
Authors: Gruza Joanna , Jurkiewicz Adrian
Published: December 2024

W artykule podjęto próbę analizy najważniejszych założeń projektu ustawy w celu ustanowienia w Polsce 35-godzinnego tygodnia pracy, skierowanego przez posłów Lewicy do Sejmu Rzeczypospolitej Polskiej we wrześniu 2022 r. W szczególności przedstawiono zmiany legislacyjne planowane w kodeksie pracy oraz wskazano przepisy przejściowe, które zakładają stopniowe obniżanie tygodniowej normy czasu pracy w Polsce. Ponadto scharakteryzowano najważniejsze skutki społeczne i gospodarcze ustawy oraz zaprezentowano nowe uprawnienia Państwowej Inspekcji Pracy. Artykuł zawiera także odniesienie do wybranych krajów Unii Europejskiej, w których dokonuje się skrócenia tygodniowego wymiaru czasu pracy. Przeprowadzono analizę danych statystycznych w zakresie średniej liczby godzin faktycznie przepracowanych w ciągu roku przez pracownika oraz średniej liczby tygodniowych godzin przepracowanych w głównej pracy przez pracownika – w Polsce, Francji, Holandii, Szwecji i Islandii.
Low-cost and easy-to-use light spectroscopy can be used to monitor release behavior of essential oils
Authors: Maisurah Syakirullah S. , Dandekar Vikrant D. , Dhaliwal Ishleen K. , Al-Gunaid Hala T.
Published: December 2024

Patchouli oil is considered a crucial ingredient for perfume, cosmetic, food and beverage manufacturing. Evaluating the volatility behavior of patchouli oil is important because it influences the aroma profile, quality, formulation, shelf life, therapeutic efficacy, and economic value of the oil. The aim of this study was to explore the ability of a low-cost and easy-to-use light-spectral triad sensor for the assessment of evaporation behavior of patchouli oil. We used a portable SparkFun Triad Spectroscopy Sensor comprised of three sensors including AS72651 (near-infrared range), AS72652 (visible range), and AS72653 (ultra-violet range). The sensor was connected to its Arduino-compatible microcontroller (SparkFun RedBoard) through Qwiic Connect System. The sensor's onboard microcontroller facilitated the collection of spectral data across 18 channels, encompassing wavelengths from 410 nm to 940 nm. The spectral data were observed qualitatively to determine the most optimum wavelength for analyzing the evaporation behavior. The data were modeled using AutoRegressive Integrated Moving Average (ARIMA). Our findings revealed that the spectral intensity is distinguishable at λ=535 nm. The ARIMA modeling indicated that the crude essential oil follows an ARIMA (0,1,0) model with drift, characterized by a negative drift parameter of -1.35 (standard error=0.33; σ2=0.74). In contrast, the heavy fraction is best described by an ARIMA (0,0,0) model with a non-zero mean of 450.33 (SE=0.35; σ2=0.86). Ljung-Box test suggested the absence of significant autocorrelation for both crude (p=0.33) and heavy fraction patchouli oil (p=0.5). In conclusion, the light spectroscopy is potential for monitoring the evaporation behavior of patchouli oil, though optimization remains necessary.
Comprehensive strategies for teaching medical english: an intercultural approach
Authors: CAZAC Viorica
Published: December 2024

Being a doctor in today’s globalized society means not only becoming a good English speaker but mainly an intercultural communicator. Since English has become a prevalent language within almost all social, cultural and scientific domains in our daily life and therefore, rightly considered as the lingua franca for science and medicine, nonnative medical students and healthcare workers experience a constant demand for an active medical terminology assessment in English: a basic requirement for their further career. However, the identity of a true medical professional involves not only the excellent command of language skills but also medical attitude and behavior of an intercultural language education. The aim of this work concerns the relationship between language and culture and the development of intercultural communicative competence, as well as understanding the challenges faced by non-native speakers, particularly the medical students or doctors. The major problem of teaching Medical English is to decide what kind of language is representative for this domain: should it include only teaching specific sets of texts and technical terminology given in course books or it should raise the student’s awareness while contrasting specialized language with daily expressions about diseases and associated medical concerns.
Contributions to the efficiency of the teaching-learning-assessment of the English language by the students from the primary classes
Authors: MOFTOLEA Dana-Maria
Published: December 2024

Effective learning of English from the first years of study comes with a series of advantages in personal development, memory, intelligence, expanding cultural horizons and communication skills in the mother tongue. The results are obtained thanks to the professionalism of the teaching staff, the attitude of the student and the partnership with the parents.
FAKTOR-FAKTOR PENYEBAB KECELAKAAN KERJA PADA PEKERJA WORKSHOP PT. CAKRA INDO PRATAMA (CIP) SITE BUKIT ASAM TANJUNG ENIM TAHUN 2023
Authors: Garmini Rahmi
Published: December 2024

Kecelakaan kerja adalah suatu kejadian yang jelas tidak dikehendaki dan seringkali tidak terduga semula yang dapat menimbulkan kerugian baik waktu, harta benda atau properti maupun korban jiwa yang terjadi di dalam suatu proses kerja industri atau berkaitan dengannya. Tujuan penelitian: untuk mengetahui faktor-faktor penyebab kecelakaan kerja pada pekerja PT. CIP Tanjung Enim. Metode Penelitian: dilakukan menggunakan uji chi square observasi, penyebaran kuesioner dan bantuan dari K3. Hasil: ada hubungan antara umur (p value 0,001), dan masa kerja (p value 0,013) terhadap kejadian kecelakaan kerja. Sedangkan variabel lama tidur (p value 0,286) tidak ada hubungan terhadap kejadian kecelakaan kerja. Simpulan: ada hubungan antara umur, masa kerja sedangkan lama tidur tidak ada hubungan dengan kejadian kecelakaan kerja.
PERBEDAAN HASIL PEMERIKSAAN TROMBOSIT YANG SEGERA DIPERIKSA DAN DITUNDA 3 JAM PADA ALAT HEMATOLOGY ANALYZER DIRUI BCC 3600 A
Authors: Toteles Aris
Published: December 2024

Pemeriksaan hitung jumlah trombosit bila disimpan pada suhu kamar  harus segera diperiksa pada interval kurang dari dua jam karena  perubahan jumlah sel darah. Pemeriksaan hitung jumlah trombosit menggunakan sampel darah EDTA stabil selama 2 jam pada suhu 200C-250C. Penundaan pemeriksaan laboratorium sering terjadi biasanya disebabkan oleh beberapa factor salah satunya pergantian shift. Tujuan Penelitian : untuk mengetahui apakah ada perbedaan hasil hitung jumlah trombosit yang di periksa segera dengan yang di periksa 3 jam dari pengambilan sampel. Metode penelitian : Penelitian ini adalah kuantitatif deskriptif analitik dengan desain penelitian one group postest only. Sampel yang diperiksa segera sebagai pretest dan sampel yang diperiksa 3 jam sebagai posttest.  Subjek penelitian yang digunakan dalam penelitian ini adalah seluruh pasien dengan permintaan darah rutin di Rumah Sakit Ernaldi Bahar Provinsi Sumatera Selatan. Darah EDTA di periksa segera dan di tunda 3 jam dari pengambilan darah dengan menggunakan Hematology Analyzer . Hasil : Hasil pemeriksaan trombosit dianalisis dengan uji T berpasangan dengan tingkat kepercayaan 95%. Rata-rata hasil hitung jumlah trombosit yang di periksa segera 358.800 mm3 hasil hitung jumlah trombosit yang di periksa 3 jam 313.966,67 mm3. Kesimpulannya, Terdapat perbedaan Hasil Pemeriksaan Trombosit Yang Segera Periksa Dan Ditunda 3 Jam Setelah Pengambilan Darah dengan nilai (sig 2 tailed) 0,000 < 0,05. Simpulan : Tidak disarankan untuk melakukan penundaan pemeriksaan trombosit.
PENATALAKSANAAN KOMPRES WATER TEPID SPONGE TERHADAP HIPERTERMIA PADA PASIEN KEJANG DEMAM DI IGD RS MUHAMMADIYAH PALEMBANG
Authors: Ansa Aldi
Published: December 2024

Latar Belakang: Kejang demam adalah kejang pada anak usia 6 bulan sampai 5 tahun yang terjdi dengan adanya peningkatan suhu tubuh lebih dari 38°C yang tidak disebabkan oleh proses intrakranial. Masalah keperawatan yang muncul pada kasus kejang demam salah satunya adalah hipertermia. Apabila Hipertermia tidak dilakukan perawatan dengan baik dapat mengakibatkan kejang berulang. Salah satu intervensi mandiri keperawatan yang dapat dilakukan untuk mengatasi hipertermia yaitu kompres water tepid sponge. Tujuan : Untuk mengetahui penerapan teknik water tepid sponge pada pasien kejang demam meliputi pengkajian, diagnosa, intervensi, implementasi, dan evaluasi. Metode : Penelitian ini menggunakan metode studi kasus pada 2 orang pasien dengan kejang demam. Hasil : Setelah dilakukan penatalaksanaan kompres water tepid songe selama 15 menit, terjadi penurunan suhu tubuh pada klien An. N dari 39°C menjadi 38,1 °C dan klien An. B 38,8 °C menjadi 38°C. Kesimpulan : Kompres water tepid sponge dapat digunakan untuk mengatasi masalah Hipertermia pada pasien dengan kejang demam. Saran : Peneliti selanjutnya dapat menerapkan penatalaksanaan kompres water tepid sponge dengan kasus lain seperti demam tifoid dan dengue hemorrhagic fever.
Kata Kunci : Hipertermia, Kompres Water Tepid Sponge, Kejang Demam
Pendidikan Kesehatan PENDIDIKAN KESEHATAN DENGAN MEDIA ULAR TANGGA TERHADAP BENCANA BANJIR AIR DI SD NEGERI 82 PALEMBANG
Authors: Winata Fina , Apriyani Apriyani , Iswari Miranti Florencia
Published: December 2024

Latar Belakang : Banjir merupakan peristiwa traumatis yang memberikan tekanan pada kesehatan mental para penyintas bencana. Bencana banjir dapat menyebabkan kerusakan terhadap pemukiman (tempat tinggal), perekonomian dan lingkungan suatu wilayah, serta kehilangan jiwa manusia. Beberapa penyebab banjir air yaitu curah hujan yang tinggi, membuang sampah sembarangan sehingga membuat selokan air tidak dapat mengalir. Salah satu bentuk pendidikan kebencanaan dalam meningkatkan pengetahuan siswa terhadap bencana banjir yaitu dengan melakukan suatu pendidikan kesehatan tentang bencana banjir dengan memberikan sebuah edukasi melalui media ular tangga. Tujuan: Diketahui pengaruh pendidikan kesehatan dengan media ular tangga terhadap bencana banjir di SD Negeri 82 Palembang. Metode: Penelitian pre experimental dengan desain one group pre and post design dengan menggunakan total sampling dengan jumlah 33 responden di SD Negeri 82 Palembang. Analisis dilakukan dengan uji Alternatif Nonparametrik Wilcoxon Sign Test. Hasil : Didapatkan nilai median pengetahuan sebelum diberikan intervensi 6,00 dan sesudah diberikan intervensi nilai median 9,00 meningkat sebanyak 3,00 dengan nilai p value 0,001 <0,05. Simpulan: ada pengaruh pendidikan kesehatan dengan media ular tangga terhadap bencana banjir Di SD Negeri 82 Palembang antara sebelum dan sesudah diberikan pendidikan kesehatan.
IMPLEMENTASI KEPERAWATAN TERAPI RELAKSASI AUTOGENIK PADA IBU HAMIL PRIMIGRAVIDA TRIMESTER III DENGAN ANSIETAS DI DAERAH BINAAN IKEST MUHAMMADIYAH PALEMBANG
Authors: Ulaa Maratun
Published: December 2024

Latar Belakang : Kehamilan merupakan kondisi perubahan citra tubuh dan peran dalam anggota keluarga. Ibu hamil biasanya menunjukkan respon psikologis dan emosional yang sama selama kehamilan diantaranya ambivalen, penerimaan, introversion, mood swings, dan perubahan gambaran tubuh, untuk menghadapi persalinan ibu yang tidak dapat beradaptasi dengan baik akan timbul kecemasan. Ansietas pada ibu hamil dalam menghadapi persalinan masih cukup tinggi. Ibu hamil yang mengalami masalah trimester III sekitar 12.230.142 juta jiwa dan 30% (8.561099) diantaranya adalah ansietas. Ansietas pada ibu hamil apabila tidak ditangani dengan serius maka akan membawa dampak dan pengaruh buruk bagi kesehatan ibu dan bayi. Sehingga perlu diberikan intervensi keperawatan. Salah satu intervensi yang dapat diberikan adalah terapi relaksasi autogenik. Tujuan : Membantu pasien untuk mengurangi tingkat ansietas dengan melakukan terapi relaksasi autogenik Metode : Penelitian ini menggunakan metode case study pada dua ibu hamil dengan teknik pengumpulan data berdasarkan ketentuan kriteria inklusi selama 6 hari dari 12 Juni 2024 s/d 17 Juni 2024. Hasil : Setelah diberikan terapi relaksasi autogenik tingkat ansietas Ny. M dengan skor 26 menjadi 13 dan Ny.T dengan skor 26 menjadi 14. Simpulan : Penerapan terapi relaksasi autogenik pada ibu hamil primigravida trimester III sangat berpengaruh terhadap penurunan ansietas. Saran : Terapi relaksasi autogenik dapat diterapkan untuk mengurangi tingkat ansietas pada ibu hamil trimester III
HUBUNGAN KECERDASAN EMOSIONAL DAN TINGKAT STRES DENGAN KESEHATAN MENTAL MAHASISWA TINGKAT PERTAMA PRODI KEPERAWATAN UNIVERSITAS AL-IRSYAD CILACAP
Authors: Engkartini Engkartini
Published: December 2024

Kesehatan mental adalah keadaan sejahtera individu yang menyadari potensi pribadinya, mampu mengatasi permasalahan saat ini dan mengatasi stres hidup secara normal serta dapat bekerja secara efektif. Bertujuan untuk mengetahui hubungan kecerdasan emosional dan tingkat stres dengan kesehatan mental. Desain penelitian ini adalah penelitian kuantitatif dengan pendekatan cross sectional. Jumlah sampel 91 mahasiswa dan menggunakan teknik total sampling. Instrumen penelitian terdiri dari kuesioner kecerdasan emosional, kuesioner PSS-10 untuk mengukur tingkat stres, dan kuesioner SRQ untuk mengukur kesehatan mental. Data yang telah diperoleh kemudian dilakukan ujian statistik rank spearman. Hasil penelitian menunjukkan terdapat hubungan antara kecerdasan emosional dengan kesehatan mental dengan kekuatan sangat rendah (p value = 0,049). Sedangkan tingkat stres dengan kesehatan mental tidak terdapat hubungan dengan kekuatan hubungan rendah (p value = 0,235). Jadi, dapat disimpulkan terdapat hubungan yang signifikan antara kecerdasan emosional dengan kesehatan mental.
literature review family support and schizophrenia relapse
Authors: Anggraini Tessy
Published: December 2024

Kekambuhan pada pasien skizofrenia merupakan masalah kesehatan mental yang kompleks dan sering kali dipengaruhi oleh berbagai faktor, termasuk dukungan sosial. Penelitian ini bertujuan untuk mengeksplorasi hubungan antara dukungan sosial dan kekambuhan pada pasien skizofrenia. Penelitian ini menggunakan pendekatan studi literatur dengan menggunakan beberapa sumber yang dipilih seperti Google Scholar, ResearchGate, DOAJ dan PubMed. Dibatasi rentang tahun 2013-2023 dan dari 20.700 GoogleScholar, 527 dari DOAJ, 244 temuan dari PubMed. Selanjutnya diseleksi literatur menjadi 20 artikel yang masuk kriteria inklusi untuk dilakukan penelitian. Hasil dari tinjauan ini adalah dukungan emosional yang positif dari keluarga berfungsi sebagai faktor pelindung yang signifikan dalam mencegah kekambuhan. Temuan ini menekankan pentingnya intervensi psikososial yang melibatkan keluarga dalam mendukung pasien skizofrenia, serta perlunya pendidikan bagi keluarga untuk menciptakan lingkungan yang mendukung pemulihan. Dengan demikian, penguatan jaringan dukungan sosial dan keterlibatan keluarga sangat diperlukan untuk mengurangi risiko kekambuhan dan meningkatkan kualitas hidup pasien.
An Overview of Management and Complications of Severe Burns and Thermal Injuries
Authors: Kashkary Suhail Mohammed , Alfaif Abdullatif Ahmed , AlGhamdi Fatima Abdullah , Alzaer Maitham Saeed , Alabbasi Atheer Ali , lawasani Zahraa Mohammed , Almatrodi Nashwa Mohammed , Alanazi Abrar Ghazai , Neama Maryam Abdulredha , Alshatti Qanot Naser
Published: December 2024

Severe burns and thermal injuries present a significant medical challenge, requiring a comprehensive approach to management and rehabilitation. The initial phase of care focuses on stabilizing the patient through fluid resuscitation, wound care, and pain management. Early excision and grafting are critical to reduce the risk of infection and improve survival outcomes. Pain management is essential to minimize the stress response and promote healing, with multimodal analgesia often employed to achieve effective control. Long-term rehabilitation is equally important, addressing physical recovery, functional restoration, and psychological well-being. Physical and occupational therapy play key roles in preventing and managing complications such as contractures, which can severely limit mobility and independence. The psychological impact of severe burns is profound, with many survivors experiencing post-traumatic stress disorder, depression, and anxiety, underscoring the need for integrated mental health support throughout the recovery process. Grafting techniques, including autografting, allografts, and innovative approaches like cultured epithelial autografts and biosynthetic grafts, are vital in restoring skin integrity and function, especially in patients with extensive burns. Complications such as infections, hypertrophic scars, and metabolic disturbances pose ongoing challenges in the care of burn patients. Rigorous infection control measures, scar management strategies, and nutritional support are essential components of comprehensive burn care. The hypermetabolic response to severe burns necessitates careful management to prevent prolonged catabolism and support wound healing. Overall, the management of severe burns requires a multidisciplinary approach that addresses the acute phase of injury, long-term rehabilitation, and the prevention and treatment of complications. Advances in burn care continue to improve patient outcomes, but the complexity of these injuries demands ongoing research and innovation to enhance recovery and quality of life for burn survivors.
Advances in Laboratory and Imaging Techniques for Detecting Minimal Residual Disease in Leukemia
Authors: Almnzlawi Ashgan Mohammed , ALaeq Rana Abdulrahim , Alotaibi Yosef Mohammed , Ahmed Khalid Mohammed , Alqahtani Sultan Ahmad , Alharbi Abdulaziz Obaid
Published: December 2024

Minimal residual disease (MRD) detection plays a crucial role in the management of leukemia, offering insights into treatment efficacy and the risk of relapse. Advances in laboratory techniques have improved the sensitivity and accuracy of MRD detection, enhancing clinical decision-making and patient outcomes. Flow cytometry, one of the most established methods, allows for the identification of leukemic cells through immunophenotypic markers, providing high sensitivity in detecting one leukemic cell among thousands of normal cells. Despite its effectiveness, challenges such as phenotypic shifts in leukemic cells and sample processing limitations remain. Molecular techniques, including quantitative polymerase chain reaction (qPCR) and next-generation sequencing (NGS), have further transformed MRD detection. qPCR provides high sensitivity by amplifying leukemia-specific genetic markers, enabling early relapse detection. NGS offers broader genomic coverage, identifying multiple mutations and clonal populations, which allows for the detection of clonal evolution and resistance. While these molecular methods are powerful, they require specialized laboratories and can be cost-prohibitive in routine settings. Emerging imaging technologies, such as positron emission tomography (PET), magnetic resonance imaging (MRI), and optical imaging, are providing new opportunities to visualize leukemic cells in anatomical locations that traditional methods may not access. These non-invasive techniques offer a complementary approach to molecular and flow cytometry methods, though challenges such as sensitivity and cost remain. The integration of these advanced technologies into clinical practice offers the potential for earlier intervention, personalized treatment adjustments, and improved long-term outcomes for leukemia patients. Continued innovation and research will be critical to overcoming current limitations and expanding the use of these methods in routine MRD monitoring. These advancements promise to reshape the landscape of leukemia management, ensuring more effective and tailored approaches to treatment and follow-up care.
An Overview of Acute Drug Overdose and Poisoning in Emergency Medicine
Authors: Aljefri Ahmed Amin , Nahhs Saud Faisal , Kheimi Rawan Mattouk , Alhamdan Abdulelah Yousef , Alharbi Turki Sanat , Alkahtani Saud Sheher , Alajmi Salem Tarheeb , Alotaibi Faisal Naif , AlJardan Badran Ahmed , Alsalmi Reema Sulaiman
Published: December 2024

Acute drug overdose and poisoning are critical concerns in emergency medicine, often arising from both intentional and unintentional exposures to harmful substances. Poisoning occurs when a substance causes harm through its chemical effects, whereas an overdose usually involves taking an excessive amount of drugs, whether by accident or on purpose. The rising incidence of drug overdoses, particularly involving opioids, sedatives and stimulants, poses significant challenges to healthcare providers. Risk factors for overdose include individual characteristics such as male gender, chronic health conditions and prior overdose experiences. Drug-related factors, including polydrug use and the route of administration, also contribute to overdose risk. Timely intervention is crucial in managing overdoses, with treatments varying based on the substance involved. For instance, opioid antagonists like naloxone are vital in reversing opioid overdoses. Prevention strategies, including harm reduction and expanded access to naloxone, are essential in addressing this public health issue. Recognizing the symptoms, risk factors and treatment options for acute drug poisoning is crucial for enhancing patient outcomes and lowering mortality rates.
A Review on Neuropharmacological Approaches to Treating Bipolar Disorder
Authors: Qattan Yaser Yahya , Aljawi Omar Abdulaziz , Alotaibi Fuad Abdulrahman , Ibrahim Leena Essam , Albulushi Hamzah Ibrahim , Alhawaj Ali Hassan , Mohammed Fatima Osman
Published: December 2024

Bipolar disorder (BD) is a severe mood disorder characterized by alternating episodes of mania and depression, with significant psychosocial impairment and an elevated risk of suicide. This review explores neuropharmacological treatments for BD, focusing on lithium, antipsychotics, antiepileptics, antidepressants and glutamatergic agents. Lithium, a cornerstone of BD treatment, offers robust efficacy in mood stabilization but has limitations due to side effects and a narrow therapeutic index. Antipsychotics, particularly atypical ones like olanzapine and quetiapine, are effective in managing mania and bipolar depression but can cause metabolic dysregulation. Antiepileptics, including valproate and lamotrigine, are used for mood stabilization, with lamotrigine particularly effective in bipolar depression. Antidepressants, while providing short-term benefits, carry risks of inducing mania and are best used cautiously. Emerging treatments like ketamine and memantine show promise in refractory cases but require further validation. Future research should focus on refining existing therapies, exploring novel agents and integrating personalized medicine approaches to enhance treatment efficacy and minimize adverse effects.
A Review on Viral Skin Infections in Children: Types, Clinical Picture and Outcomes
Authors: Salman Ali Aljowharah , Madani Fatema Hosam , Baqasi Ahmed Mohammedsaeed , Alshammari Sultan Musallam , Aldogil Seham Omar , Alaeq Rana Abdulrahim
Published: December 2024

Viral skin infections in children encompass a broad spectrum of conditions with diverse clinical manifestations and outcomes. These infections are caused by various viruses, including Herpes Simplex Virus (HSV), Varicella-Zoster Virus (VZV), Human Papillomavirus (HPV), Molluscum Contagiosum, and Coxsackievirus. Each virus presents with unique clinical features and management needs. Herpes Simplex Virus (HSV) infections, which include oral herpes, herpetic whitlow, and eczema herpeticum, present as painful vesicular lesions. HSV-1 typically affects the oral region, while HSV-2 is more common in genital infections. Herpetic gingivostomatitis and eczema herpeticum can cause extensive oral lesions and severe symptoms, requiring antiviral therapy for severe cases. Varicella-Zoster Virus (VZV) causes chickenpox, characterized by a rash that evolves through macules, papules, vesicles, and crusts, often accompanied by fever. Vaccination has significantly reduced the incidence and severity of VZV infections, but severe cases can still occur, particularly in vulnerable populations. Human Papillomavirus (HPV) infections present as warts on various body parts, including common warts, plantar warts, and flat warts. While many HPV warts are self-limiting, persistent or painful warts may require treatment with cryotherapy, topical therapies, or laser therapy. Molluscum Contagiosum, caused by a poxvirus, manifests as dome-shaped, umbilicated papules on the skin. The lesions are generally painless but can cause cosmetic concerns and secondary bacterial infections. Treatments include cryotherapy and topical therapies, though the infection often resolves spontaneously over several months. Coxsackievirus infections are known for causing Hand, Foot, and Mouth Disease (HFMD), presenting with a rash and oral lesions, along with systemic symptoms like fever. Severe manifestations, such as aseptic meningitis and myocarditis, are less common but require specific medical management. Vaccination and early treatment can mitigate severe outcomes and improve quality of life for affected children.
The Role of Oral Hygiene in Preventing Secondary Infections in Children with Immunocompromising Conditions
Authors: Zafer Roaa Mubarak , Alnasser Shoruq Ali , AlJaffar Eman Ali , Alahmadi Rahaf Yousif , Alalawi Amirah Ibrahim
Published: December 2024

Immunocompromised children are particularly vulnerable to infections, including those originating from the oral cavity, due to their weakened immune systems. Oral hygiene plays a pivotal role in preventing secondary infections, which can arise from bacterial, fungal, and viral colonization in the mouth. Poor oral hygiene allows pathogenic microorganisms to flourish, increasing the risk of systemic infections such as bacteremia, sepsis, and pneumonia. The mechanisms linking oral health to systemic infections are multifaceted, involving disrupted microbial balance, impaired immune responses, and weakened mucosal barriers. Opportunistic pathogens such as Streptococcus mutans, Porphyromonas gingivalis, and Candida species often proliferate in the oral cavities of these children, leading to conditions like dental caries, periodontitis, and oral candidiasis. Preventive oral hygiene strategies for immunocompromised children include daily toothbrushing with fluoride toothpaste, flossing, and the use of antimicrobial mouth rinses such as chlorhexidine. Chlorhexidine has been shown to significantly reduce the incidence of oral mucositis and related secondary infections. Saliva substitutes and sodium bicarbonate mouthwashes help mitigate the effects of xerostomia, a common side effect of treatments like chemotherapy, which exacerbates the risk of oral infections. In high-risk cases, antibiotic prophylaxis before invasive dental procedures reduces the likelihood of bacteremia, with studies reporting up to 72% reduction in post-procedural infections. Professional dental care, including regular cleanings and the application of fluoride varnishes and sealants, also plays a critical role in preventing infections. Together, these preventive measures reduce the microbial load, support oral tissue integrity, and protect immunocompromised children from potentially lifethreatening secondary infections. Emphasizing the integration of oral hygiene into the overall care plan for immunocompromised children is crucial for reducing morbidity and improving their quality of life.
Evaluation of Biomaterials Used in Guided Tissue Regeneration
Authors: Munshi Maha Assad , Alsaleh Fai Adel , Aljehani Nassreen Yousef , Almusaad Mashael Mohammed , Alolaian Reem Khalid , Alshammari Amjad Zayed , Eissa Renad Hamza
Published: December 2024

Guided tissue regeneration (GTR) is a key technique in periodontal therapy, aimed at restoring lost periodontal structures such as bone, periodontal ligament, and cementum. Biomaterials play a crucial role in the success of GTR by serving as barriers that selectively allow tissue regeneration. The choice of biomaterials used in GTR has evolved over the years, encompassing non-resorbable options like expanded polytetrafluoroethylene (ePTFE) and resorbable materials such as collagen-based membranes and synthetic polymers. Each type of biomaterial presents unique benefits and limitations. Non-resorbable materials provide excellent mechanical stability but require a second surgery for removal, while resorbable membranes eliminate this need but may degrade unpredictably, affecting regeneration outcomes. Biocompatibility and degradation properties of these materials are central to their effectiveness. Natural biomaterials, such as collagen, offer superior biocompatibility, mimicking the extracellular matrix to promote cell attachment. However, synthetic materials, including polylactic acid (PLA) and polyglycolic acid (PGA), offer more predictable degradation rates, but their byproducts can cause localized inflammation, posing challenges to their clinical application. Composite biomaterials are emerging as a potential solution, combining the strengths of natural and synthetic materials to optimize both biocompatibility and mechanical support. Clinical applications of GTR include the treatment of infrabony and furcation defects, as well as gingival recession. GTR has shown significant potential in these areas, with varying degrees of success depending on defect type and patient factors. Challenges in biomaterial development persist, particularly in balancing mechanical stability with bioactivity, and achieving predictable degradation rates. Future research is likely to focus on the incorporation of bioactive agents and the use of nanotechnology to create smart biomaterials that can dynamically respond to the healing environment, enhancing tissue regeneration and clinical outcomes.
PEMANFAATAN AIR SUMUR BOR MENJADI AIR MINUM DALAM KEMASAN DENGAN REVERSE OSMOSIS DI KALURAHAN SERUT GEDANGSARI GUNUNG KIDUL
Authors: Qonitatul Hidayah  , Kusuma Damar Yoga , Ardi Subhan Zul , Suwartiningsih Nurul , Rahmadhia Safinta Nurindra
Published: December 2024

Pengelolaan air bersih di Kalurahan Serut telah dikelola oleh Badan Usaha Milik Kalurahan (BUMKal) Karya Manunggal Jaya sejak tahun 2017. Pendistribusian air bersih yang belum merata ke masyarakat karena biaya pemasangan ke rumah masih relatif mahal. Hal ini menyebabkan pemerintah kalurahan Serut dan BUMKal menginisiasi pengelolaan air sumur bor menjadi air minum dalam kemasan (AMDK) untuk meningkatkan profit BUMKal dan menambah pengelolaan air bersih. Untuk merintis unit bisnis pengelolaan air diperlukan pengujian kelayakan air tanah terlebih dahulu. Salah satu metode yang digunakan untuk pengujian kelayakan air adalah metode filtrasi dan sterilisasi. Kualitas air tanah harus diuji untuk mengetahui kandungan bakteri serta serangkaian uji fisis dan kimiawi. Oleh karena itu, proses flukulasi dan filtrasi diperlukan untuk menghilangkan endapan lumpur, bakteria dan kandungan logam berat dari air tanah. Selanjutnya air tanah perlu disterilisasi dengan radiasi ultraviolet maupun proses klorinasi untuk menghilangkan virus dan bakteria. Hasil uji laboratorium air yang belum di filtrasi dan sterilisasi menunjukkan kandungan coliform serta mangan. Setelah dilakukan filtrasi dan sterilisasi dengan menggunakan reverse osmosis, hasil uji laboratorium air tanah menunjukkan tidak ada kandungan bakteri ataupun logam berat. Hasil pengujian air sumur bor telah memenuhi standar baku air minum kemasan, sehingga air layak untuk dikonsumsi secara langsung.
PELATIHAN PENTINGNYA MEDIA SOSIAL DALAM PEMASARAN UMKM LANG LING LUNG KUDUS
Authors: Supriyati Endang , Listyorini Tri , Mulyani Sri , Budiman Nita Andriyani , Iqbal Mohammad
Published: December 2024

Usaha Mikro, Kecil, dan Menengah (UMKM) mepunyai peran sangat penting bagi kerangka ekonomi Indonesia dalam memberikan kontribusi yang signifikan terhadap lapangan kerja dan stabilitas ekonomi. Banyak UMKM yang masih kurang siap untuk memanfaatkan media sosial secara efektif untuk pemasaran. UMKM Lang Ling Lung di Kudus berusaha memanfaatkan media sosial untuk meningkatkan kehadirannya di pasar dan mendorong pengingkatan penjualan. Pelatihan yang dipelopori oleh Tim Pengabdian kepada Masyarakat Universitas Muria Kudus ini ber tujuan membekali UMKM dengan keterampilan pemasaran digital yang dibutuhkan untuk berkembang di pasar yang semakin kompetitif. Metode yang digunakan dalam pelatihan adalah model lokakarya interaktif yang berisi materi dasar pemasaran media sosial, pengembangan strategi konten, dan  teknik interaksi pelanggan. Hasil yang diharapkan melalui kegiatan pelatihan ini yang dirasakan oleh kemanfaatannya oleh UMKM, adalah meliputi pengembangan strategi pemasaran media sosial dasar, pembuatan konten atau postingan menarik di media sosial, pemanfaatan alat analitik untuk melacak kinerja pemasaran, dan pemberdayaan peserta untuk bisa berinteraksi lebih efektif dengan pelanggan.
Pengaruh Empowerment Leadership Terhadap Kinerja Guru di SMP Negeri Se Kecamatan Mesuji
Authors: Wahyuti Yuli , Lestari Neta Dian
Published: December 2024

This study aims to analyze the effect of empowerment leadership on teacher’s performance in junior high schools in Mesuji District. The approach used is a literature review, by collecting and analyzing various relevant research results in national journals related to empowerment leadership and teacher’s performance. Through a literature review, this study discusses the concept of empowerment leadership, which involves empowering teachers to make decisions, support in developing competencies, and increasing work motivation. This study collects literature from national journals published in the last four years, with an analysis focused on research results that measure the impact of empowerment leadership on improving teacher performance, both directly and indirectly. The results of the study indicate that empowerment leadership has a significant positive effect on teacher’s performance, especially in terms of motivation, job satisfaction, and commitment to the school. Teachers who feel empowered by the principal tend to have better performance, as indicated by improved teaching quality and involvement in school activities. The novelty of this study lies in its focus on the local context in junior high schools in Mesuji District, which has so far been underrepresented in the literature. The contribution of this research is to provide a clearer picture of the importance of empowerment leadership in improving teacher’s performance, which can be a reference for regional education policy makers in designing school leadership programs.
Finding Standard Levels for Some Special Physical Fitness Elements and Basic Skills of Volleyball for Juniors in the Middle Euphrates Clubs
Authors: Hussein Ali Radhi Abdul , Hrebid Nabeel Kadhim
Published: December 2024

Since tests and measurements are thought of as the fundamental sports tests that reveal the true level that the player reaches, they shed light on the secrets of the ability so that the coach can know the true level of the players to achieve good results. This highlights the significance of the research by identifying standard levels for young volleyball players through specific physical fitness elements and basic skills using evaluation tools. Regarding the research problem, although there are several tests for the components of particular physical fitness and fundamental volleyball skills, the results only provide raw values that are meaningless to the coach. Therefore, in order to assess the components of unique physical fitness and fundamental skills, these raw scores need to be transformed into standard ratings. We can establish benchmarks and levels for junior volleyball players in the Middle Euphrates clubs by assessing their actual physical attributes and fundamental ball skills. The purpose of the study was to determine the degree of fundamental skills and unique physical fitness components among junior volleyball players in the Middle Euphrates clubs. Establishing benchmarks for assessments of particular physical fitness components and fundamental abilities for young volleyball players in the Middle Euphrates clubs. In order to address the nature of the study problem, we employed a descriptive technique that made use of the survey method as well as relationships and correlations. The research sample's highest percentage in the preparation, agility, and strength tests was at the standard level (good), according to the most significant findings. Additionally, the research sample's maximum percentage in the speed tests was at the standard level, or average. Additionally, the research sample's lowest percentage in the spiking test was at the standard level, which is quite poor.
Pengetahuan Perawatan Kaki pada Pasien Diabetes Mellitus
Authors: Sari Lisa Anita , Dasuki Dasuki
Published: December 2024

Diabetes Melitus (DM) dapat diartikan sebagai gangguan yang menyebabkan glukosa darah meningkat akibat gangguan atau defisiensi produksi insulin yang ditandai dengan kondisi hiperglikemia. DM disebabkan karena tubuh kekurangan insulin akibat berkurangnya massa dan/atau fungsi dari sel beta pankreas. Penderita Diabetes Melitus yang tidak terobati dapat menimbulkan komplikasi baik mikrovaskuler maupun makrovaskuler. Penyakit Diabetes ini merupakan penyakit yang berbahaya, jika dalam jangka waktu lama jika tidak teratasi dapat menyebabkan kerusakan organ lainnya, salah satunya ulkus diabetikum yang dapat dicegah dengan perawatan kaki. Penelitian ini bertujuan untuk mengetahui gambaran pengetahuan perawatan kaki pada pasien DM di wilayah kerja Puskesmas Putri Ayu, Kota Jambi. Penelitian ini merupakan penelitian deskriptif. Responden dalam penelitian sebanyak 96 orang. Teknik pengambilan sampel menggunakan teknik accidental sampling. Analisis data yang digunakan yaitu analisi univariat. Hasil penelitian menunjukkan bahwa sebagian besar responden 57% memiliki pengetahuan yang kurang baik terhadap perawatan kaki pada pasien DM. Diharapkan agar petugas kesehatan untuk terus memberikan edukasi kesehatan tentang pentingnya melakukan perawatan kaki pada pasien DM dan demonstrasi tentang bagaimana cara perawatan kaki pada pasien DM. Penjelasan yang diberikan hendaknya dengan menggunakan bahasa yang mudah dimengerti agar responden dapat memahami dengan baik dan juga dengan cara memberikan leaflet, brosur, dan kegiatan promotif lainnya seperti melakukan diskusi bersama.
Strategi Pengembangan Kawasan Minapolitan di Sumatera Barat Menggunakan Analytical Hierarchy Process
Authors: Viarani Suci Oktri , Nesti Lisa , Mufti Wahyu Fitrianda
Published: December 2024

West Sumatra Province has been designated by the Minister of Maritime Affairs and Fisheries as a Minapolitan area with seven regions in West Sumatra. Since the establishment of West Sumatra as a Minapolitan area, there has been no research examining the evaluation of suitability between planning and implementation of the Minapolitan fishing area development program in West Sumatra. The aim of this research is to determine a strategy for developing the Minapolitan area in West Sumatra which can improve the welfare of fishermen in the area. The data collection technique in this research is the primary data collection method in the form of field observations, interviews, FGDs and filling out questionnaires by respondents selected based on their knowledge of the Minapolitan area development program, such as representatives of the DKP, Port Service, business actors, and fishermen figures. The method used to determine strategic priorities for developing the Minapolitan area is using the Analytical Hierarchy Process approach. Based on the AHP calculation, the CR value <= 0.1 shows that respondents are consistent in making assessments and the resulting solutions are optimal. Likewise, for the CR value in the calculation for the assessment of each indicator, the CR value obtained is 0.0263 for the assessment of the supporting facility factor indicator, 0.0231 for the assessment of the supporting infrastructure factor indicator and 0.0061 for the assessment of the regional program factor indicator.The strategy obtained for developing the Minapolitan area is seen from the priority value between the highest factors, namely the supporting facilities and supporting infrastructure factors. The priority indicators that need to be immediately improved are the indicators for the availability of fishing ports, followed by the availability of fishing gear and the availability of clean water networks, the results obtained from the priority order of all the indicators assessed.
IDENTIFIKASI CEMARAN BAKTERI SALMONELLA PADA GULA CAIR MENGGUNAKAN REAL TIME-POLYMERASE CHAIN REACTION DAN MEDIUM SPESIFIK
Authors: Putri Melysa , Subriadi Fejri , Syafrinal Syafrinal , Hafnimardiyanti Hafnimardiyanti , Armin M. Ikhlas , Putri Annisa
Published: December 2024

The development of the food and beverage industry has led to an increasing demand for the availability of liquid sugar. To ensure the hygiene of liquid sugar products, quality control is necessary, one of which is through microbiological analysis. This study aims to identify the presence of Salmonella sp. in liquid sugar produced by PT XYZ using microbiological and genetic analysis methods. The methods applied include bacterial inoculation on Xylose Lysine Deoxycholate (XLD) agar as a specific medium and Real-Time Polymerase Chain Reaction (RT-PCR) to detect bacterial DNA. The results showed no color changes in the XLD medium that would indicate the presence of Salmonella sp. Additionally, the RT-PCR results did not show amplification in the samples, except for the positive control. This indicates that the tested liquid sugar products are free from Salmonella sp. contamination, demonstrating the effectiveness of good sanitation and storage practices during production.