bluuebunny/crossref_metadata_2025 huggingface dataset:
Фармакологические свойства ацетилсалициловой кислоты и ее комплекс с глицирризиновой кислотой как перспективная лекарственная форма (обзор)
Authors: Хисамутдинова Регина Ю. , Балтина Лидия А. , Сапожникова Татьяна А.
Published: February 2024

В предлагаемом обзоре обобщены современные литературные данные исследований механизма антитромботического, противовоспалительного, жаропонижающего эффектов широко применяемой в медицине ацетилсалициловой кислоты (АСК). Применение АСК может сопровождаться возникновением ряда осложнений со стороны желудочно-кишечного тракта (язвы и кровотечение), нефротоксичностью, гастротоксичностью, развитием бронхоспазма (аспириновая триада), а также клиническими проявлениями аспирин-резистентности. В обзоре обсуждаются достоинства и недостатки основных методов профилактики нежелательных побочных явлений при приеме низких доз АСК: использование ингибиторов протонного насоса, применение ребамипида, а также комплексов включения АСК как перспективных лекарственных форм. Рассмотрены фармакологические свойства глицирризиновой кислоты (ГК) и ее способность к эффекту клатратообразования с известными лекарственными препаратами, в частности с АСК. Показаны преимущества лекарственной формы ГК с АСК с сохраненной или улучшенной фармакологической активностью и сниженными побочными эффектами последней. В обзоре представлены данные из отечественных и зарубежных источников, полученные в результате поиска в российских и международных системах PubMed, eLibrary за последние 10 – 11 лет.
Применение технологий виртуальной реальности в фармации
Authors: Колосов Юрий Анатольевич , Куркин Д. В. , Горбунова Ю. В. , Бакулин Д. А. , Робертус А. И. , Иванова О. В. , Бузина Т. С. , Шалина О. С. , Денисов А. А. , Котельникова А. В. , Мурсалов И. Д. , Нарышкин И. М.
Published: February 2024

В статье проанализированы и обобщены литературные данные о применении виртуальной реальности в различных сферах деятельности, перспективы развития и возможные ограничения распространения данной технологии в фармации в Российской Федерации и во всём мире. Рассматривается актуальность внедрения технологии виртуальной реальности в российское фармацевтическое образование на различных уровнях профессиональной подготовки специалистов для отрасли.
Влияние стандартной лекарственной терапии на уровень окислительного стресса, мРНК фактора некроза опухоли-α и рецепторов для конечных продуктов гликирования у пациентов с диабетической нейропатией
Authors: Образцова Ирина А. , Попов Сергей С. , Крыльский Евгений Д. , Верёвкин Алексей Н. , Пашкова Анна А. , Попова Татьяна Н.
Published: February 2024

Одним из наиболее тяжелых осложнений сахарного диабета (СД) является диабетическая нейропатия (ДНП), развитие которой сопряжено с нарушением окислительно-восстановительного гомеостаза в нейронах и усилением воспалительной реакции в результате активации транскрипции рецепторов для конечных продуктов гликирования (receptors for advanced glycation end products, RAGE). Исходя из этого, интерес представляет анализ эффективности терапии ДНП с применением фармакологических веществ, обладающих антиоксидантной и противовоспалительной активностью. Целью настоящей работы стало изучение влияния стандартной терапии СД 2 типа на окислительный статус и уровень мРНК фактора некроза опухоли-α (ФНО-α) и RAGE в клеточной фракции крови больных с ДНП. В одноцентровое проспективное нерандомизированное исследование были включены 45 пациентов в возрасте от 46 до 80 лет с СД 2 типа и ДНП. Выявлена сильная и средняя корреляция между показателями гликемии (концентрация глюкозы натощак и постпрандиальная концентрация глюкозы), неврологического (амплитуда М-ответа, r =-0,503 и -0,490) и окислительного статуса (максимальная вспышка биохемилюминесценции, r = 0,784 и 0,759), уровнем мРНК ФНО-α (r = 0,752 и 0,797) и RAGE (r = 0,740 и 0,692) в клеточной фракции у участников исследования. Обнаруженные корреляционные связи свидетельствуют о значительной роли нарушения окислительного статуса, а также активации ФНО-α и RAGE в патогенезе ДНП. Результаты работы показали, что проведение базисной лекарственной терапии на протяжении 14 дней приводило к снижению уровня гликемии на 44 % (p < 0,001) и выраженности неврологического дефицита в среднем на 21 % (p < 0,01) у пациентов. Кроме этого, происходило уменьшение интенсивности свободнорадикального окисления и повышение общей антиоксидантной активности в сыворотке крови на 27 % (p < 0,01), уменьшение уровня мРНК ФНО-α и RAGE в среднем на 64 % в клеточной фракции крови больных ДНП (p < 0,01) и понижение скорости оседания эритроцитов на 37 % (p < 0,001). По-видимому, в результате гипогликемического эффекта базисной лекарственной терапии имело место снижение активации RAGE и экспрессии гена ФНО-α, что, наряду с антиоксидантными свойствами тиоктовой кислоты и ингибиторов дипептидилпептидазы-4, могло вносить вклад в уменьшение интенсивности воспаления и улучшение окислительного статуса у пациентов.
Влияние фитоэкдистероидов на показатели липидного обмена у крыс и кроликов
Authors: Сыров В. Н. , Шахмурова Гульнара Абдуллаевна , Саидходжаева Д. М.
Published: February 2024

Фитоэкдистероиды — туркестерон и циастерон (выделены из Ajuga turkestanica) при пероральном введении (5 мг/г, однократно) крысам незначительно, а при многократном (в течение 3 мес) применении достоверно снижают содержание общего холестерина в сыворотке крови на 18,9 и 20,4 %, а триглицеридов на 17,8 – 19,4 % (p ≤ 0,05). В условиях эндогенной и тритоновой (тритон WR-1339) гиперлипидемии фитоэкдистероиды оказывают более выраженное гипохолестеринемическое действие (для туркестерона 28,1 – 26,5 %, для циастерона 37,2 – 41,2 %, p ≤ 0,05) и гипотриглицеридемическое действие (соответственно 19,5 – 30,2 % и 22,0 – 50,9 %, p ≤ 0,05). По эффективности циастерон не уступает клофибрату. Туркестерон и циастерон при введении кроликам с атеросклерозом снижают уровень холестерина в сыворотке крови на 40,5 – 60,3 %, в аорте — на 50,3 – 71,6 % и в печени — на 30,9 – 64,5 % (p ≤ 0,05). Уровень триглицеридов снижается в сыворотке крови на 41,0 – 54,2 %, а в печени — на 35,4 – 63,8 % (p ≤ 0,05). Холестериновый индекс атерогенности уменьшается на 49,7 – 69,3 % (p ≤ 0,05). Действие циастерона было более выраженным, чем действие туркестерона.
Рeculiarities of studying academic disciplines in safety sciences in crisis time
Authors: Haladzhun Yaroslav , Myts Ihor , Petryshyn Roman , Yaremko Zinoviy
Published: February 2024

The COVID–19 pandemic and the russian invasion of Ukraine in 2022 accelerated the digitalisation of the educational process. In particular, it has led to the transition to distance learning and revealed the readiness of the participants of the educational process for new challenges. This work experience is unique and requires the disclosure of the peculiarities of teaching and studying individual disciplines and the generalisation of the didactic characteristics of distance/blended learning. According to the results of two sociological surveys conducted among our students at the end of the first semester of the 2020/2021 and 2022/2023 academic years, the peculiarities of distance/blended learning and their impact on students’ health/well-being were revealed. Students use desktop computers, laptops, tablets, and smartphones for distance learning and confirm the convenience of their use. An essential point during distance learning is access to the Internet and its quality. The difficulty of perceiving information and performing practical tasks during remote classes also required a certain period of adaptation to new learning conditions. The considerable duration of work in front of the screen and the frequently improperly equipped educational place had a particularly negative impact on the well-being of students. The survey results revealed certain problems faced by students, associated with motor activity and sleep duration caused by long-term use of gadgets. The appearance of specific reactions of the body to stress in crises was assessed. It is shown that the study of the discipline «Life and Occupational Health and Safety» helped students adapt to the changed study conditions. We have concluded that the improvement of approaches to distance/blended learning is important in the context of the further digitalisation of education and their role in increasing the efficiency of the educational process in classroom learning conditions in the post-war period. Keywords: adaptation, safety of the educational process, distance learning, blended learning, crisis, assessment.
Culture as a fundamental category of humanitarian discourse in the context of studying the formation of professional thinking culture of future teachers
Authors: Kovalchuk Larysa
Published: February 2024

The article is devoted to the study of the issue of developing the culture of professional thinking of future teachers. In this context the conceptual and terminological analysis of the essence of key concepts is carried out. Considering that culture is a system-forming, generic concept, the key categories («personality culture», «professional and pedagogical culture», «culture of professional thinking», etc.) are considered as generic. The author of the article analyzes the approaches of researchers to the interpretation of the essence of culture as a fundamental category of the humanitarian discourse in philosophy, cultural studies, sociology, psychology, and pedagogy. Based on the study, it is concluded that interpretations of the essence of culture have become widespread in humanitarian discourse, focusing on the ontological, anthropological, axiological, activity, heuristic, mental and semiotic aspects. It is determined that the difference in the approaches of scholars to the interpretation of the essence of culture is due to the complexity, ambiguity, multidimensionality and multifunctionality of the analyzed phenomenon, and is also related to the problematic field of specific scientific research. It has been found that culture, society, professional (social) community and personality are connected by multifaceted interconnections and mutual influences in the system: «culture–society culture–professional (social) community culture–individual culture». We consider the professional and pedagogical culture as the culture of a professional community, which organically combines the culture of professional thinking, pedagogical orientation, values, pedagogical abilities, professional competence, pedagogical experience, creative activity, personal and professional qualities of a teacher, etc. Keywords: discourse, category, culture, personality culture, society culture, culture of professional community, culture of professional thinking of a teacher, professional and pedagogical culture.
Experience of using simulation-based learning technology in continuous professional development of medical rehabilitation nurses
Authors: Rudakova Nataliia
Published: February 2024

Every profession has its own professional standards that professionals develop during their activities and identify with in their professional role. The professional standard is an essential component of medical professions, as its purpose is to enable healthcare personnel to justify and reflect on their actions during practical activities. This justification and reflection allow taking responsibility for medical tasks confidently and representing the profession both internally and externally. In the medical field, the professional standard also acknowledges that contemporary knowledge is constantly evolving, requiring continuous professional self-realisation, leading to the achievement of stability in expertise and professionalism. Ultimately, the concept of a «professional standard» also signifies active participation in the education and support of future healthcare professionals, elevating the importance of one’s profession on both professional and societal levels. This outcome can be achieved through active participation in continuous professional development events for healthcare workers, including medical rehabilitation nurses. Research by domestic and foreign scholars regarding the development of continuous professional education for nurses has been analysed. A retrospective examination of the evolution of continuous professional education in nursing in Ukraine from the mid-20th century to the first half of the 21th century has been conducted, alongside an analysis of existing state regulatory legal acts and orders. The rationale for incorporating elements of simulation-based learning into the system of continuous professional education for medical rehabilitation nurses has been established, specifically in the context of reforming the rehabilitation sector amidst the armed conflict. The experience of using simulation-based learning elements in an informal format of continuous professional development (CPD) is also discussed. Keywords: nursing, continuous professional development, rehabilitation assistance, simulation-based learning.
Features of social and psychological adaptation of military personnel who participated in combat operations
Authors: Subashkevych Iryna , Bordiyan Yaroslav , Halko Solomia
Published: February 2024

The article considers the specific aspects of social and psychological adaptation of the military personnel after returning to civilian life. The authors of the article describe the psychological characteristics and ability of the military to socialize after the war. A number of methods were used to assess the psychological state of the military. The researchers define the social and psychological adaptation of military personnel as the result of changes in social, psychological, ethical, economic and demographic relations, as well as the adjustment of individuals to the existing social environment. The peculiar features of this adaptation are active conscious participation, the impact of human activity on the environment and the results of the changes in response to social context. The study was conducted at the «Tysovets» sports and military base among the servicemen aged 25 to 45. The researchers used various methods to analyze social and psychological adaptation, including the Adaptability-200 questionnaire for studying neuropsychological stability and resistance to deviant behavior, the 16-factor R. Kettell questionnaire for personality analysis, the Leongard-Schmiszek questionnaire for diagnosing personality accentuation, and a survey to determine the readiness of military personnel to adapt to the conditions of everyday civilian life. The results of the study showed that military personnel demonstrate a high level of neuropsychological stability and easily adapt to new challenges. They are not concerned about changes in their professional activities and adapt to them with ease. However, some individuals show signs of addictive and delinquent behavior. The analysis of the Kettell methodology revealed that many of them have a high degree of withdrawal and a low history of socializing with civilians. They have difficulty establishing contact with others and often categorize people as «friends» and «strangers». The veterans also demonstrated the low level of tolerance to frustration and irritability that can lead to neurotic symptoms. The Leongard-Schmiszek methodology proved that many military personnel have an anxiety type of personality accentuation, accompanied by severe agitation and restlessness. This can affect their ability to regulate their emotions and social relationships. Overall, the study highlights the importance of psychological support and assistance to veterans in the process of their social and psychological adaptation after returning from war. Keywords: adaptation, military personnel, psychological characteristics, social and psychological adaptation.
Peculiarities of organisational and pedagogical conditions for the formation of emotional intelligence of future primary school teachers
Authors: Yaremchuk Nataliia , Samardak Yulia
Published: February 2024

The article reveals the peculiarities of forming the emotional intelligence of future primary school teachers in view of the new changes in pedagogical education according to the «New Ukrainian School» Concept and the professional standard «Primary school teacher of general secondary education». A review of foreign and Ukrainian scientific research on the features of emotional intelligence as a psychological and pedagogical phenomenon and a component in the professional training of a future teacher is carried out. The article provides a definitional analysis of the concept of «emotional intelligence», and considers the content and structural characteristics of future primary school teachers’ emotional intelligence as a necessary component of a teacher’s professional competence. The organisational and pedagogical conditions for the formation of emotional intelligence in accordance with the peculiarities of the formation of emotional intelligence in the professional and personal development of the future teacher are presented: the development of emotional intelligence affects the professionalism of the activity and the professionalism of the personality of a future primary school teacher, the formation of pedagogical skills as an indicator of professional success; the projection of the educational environment for the training of a future primary school teacher should provide for emotionally positive influences in the system of components – socio-cultural, spatial-subject, activity, resource, information and communication, axiological; systemic changes in the organisation of primary school teacher training to introduce emotional intelligence content in the components of the pedagogical process for relevant disciplines of the normative and elective cycle, as well as in non-formal education; conceptual introduction of the idea of developing emotional intelligence a professional skill formed within the framework of the educational and professional programme in the speciality 013 «Primary Education». Recommendations are given for the implementation of organisational and pedagogical conditions in the process of training future teachers in order to improve the formation of their emotional intelligence. Keywords: primary school teacher training, emotional intelligence, New Ukrainian School, organisational and pedagogical conditions, emotional competence.
Factors Influencing Community Interest in Savings at Bank XYZ Branch: Analysis Comparative Model
Authors: Lestari Sandi , Fakhri Ulumuddin Nurul , Nuriyah Aminah , Sunandar Nandar
Published: February 2024

The imbalance between the number of Indonesian Muslims and the interest in saving in Islamic banks makes for a very interesting problem to study. This study aims to look at the factors that influence interest in saving in sharia banks, especially the Bank XYZ Branch. This research uses descriptive and quantitative methods. The tools used are distributing questionnaires to 43 Bank XYZ Branch customers with the likerts approach; besides that, this research uses two models, namely the ANN (artificial neural network) and partial least squares (PLS-SEM) models. The sample obtained from this study was 43 customers with various professions. The result of this research is that the religious knowledge factor is the factor that most influences interest in saving, with a value of 42.02%, followed by a promotional factor of 38.36%. While the product factor is not very influential with a value of only 19.61%, it is no different from the results of PLS-SEM, namely that religious knowledge and promotion are the most influential things significantly, while bank products do not affect saving in Islamic banks. The results of this study can help Islamic banking parties, especially the Bank XYZ Branch, map prospective customers who want to be prospected.
Influence of Emotional Marketing and Sharia Marketing on Consumer Decisions in Purchasing Waqf Policy Insurance Products (Case Study at PT Asuransi Syariah Keluarga Indonesia)
Authors: Marsela Indri , Devi Abrista , Hakim Nurman
Published: February 2024

Abstract. The development of sharia economics and finance has experienced significant developments in recent years. This is marked by several main developments in the financial sector and sharia financial instruments, which are increasingly varied and diversifying to meet the diverse needs of the public or customers. One of the sharia financial institutions that is experiencing development is sharia insurance. The sharia insurance industry has become an integral part of modern society's lives. In the midst of the various choices of sharia insurance products, innovation in sharia insurance products combined with waqf instruments is one of the good things for the expansion of sharia financial instruments. Companies marketing waqf insurance policies face increasingly complex challenges to understand, reach, and win the hearts of consumers. The decision to purchase a waqf policy insurance product no longer only revolves around financial considerations but also includes emotional dimensions and deep religious values. This research aims to determine the influence of emotional marketing and sharia marketing on consumer decisions in purchasing policy waqf insurance products using the method used by researchers, namely associative research with a quantitative approach. This research used a sample of 40 respondents with 19 questionnaire statements. In this study, the model used uses a linear regression model involving more than one independent variable or predictor (multiple linear regression). This research shows that, partially or simultaneously, the emotional marketing and sharia marketing variables are stated to have a significant influence on consumer decisions in purchasing waqf insurance policies. This is obtained from the coefficient of determination value in the very strong category, which is between 0.80 and 1,000, with an adjusted R square result of 0.818, or around 81.8%, influencing consumer decisions and the remaining 18.2% being influenced by other variables outside of this research.

Keywords: Emotional Marketing, Sharia Marketing, Consumer Decisions, Waqf Insurance Policies.
Hubungan Mekanisme Koping dengan Kualitas Hidup pada Pasien Fraktur di Poliklinik Orthopedi Rumah Sakit Bhayangkara Jambi
Authors: Caesar Silvana Medilia , Mekeama Luri , Sari Putri Irwanti
Published: February 2024

Fraktur merupakan patah tulang yang membutuhkan penanganan dan perawatan yang tepat. Keterlambatan atau kesalahan penanganan akan menimbulkan komplikasi yang berdampak kepada kualitas hidup pasien, untuk itu dibutuhkan mekanisme koping yang baik dalam mengatasi masalah fraktur. Penelitian ini bertujuan untuk mengetahui hubungan antara mekanisme koping dan kualitas hidup pada pasien dengan fraktur. Penelitian ini menggunakan desain penelitian kuantitatif korelasional dengan pendekatan cross-sectional, jumlah populasi 121 pasien fraktur, diperoleh 61 pasien sebagai sampel penelitian dengan menggunakan teknik pengambilan sampel accidental sampling, alat ukur kuesioner brief COPE dan WHOQoL-BREF dengan cara wawancara terpimpin, analisis data menggunakan uji alternatif fisher’s exact test. Didapatkan karakteristik responden berdasarkan mayoritas berusia 12-25 tahun 37,7%, jenis kelamin laki-laki 65,6%, pendidikan SMA 52,5%, pekerjaan sebagai pelajar 32,8%, lama pengobatan >1-12 bulan 59%, gambaran mekanisme koping 67,2% kategori adaptif, gambaran kualitas hidup 78,7% kategori baik. Nilai p-value untuk hubungan antara mekanisme koping dan kualitas hidup adalah 0,003. Terdapat hubungan yang signifikan Mekanisme Koping dengan Kualitas Hidup pada Pasien Fraktur di Poliklinik Orthopedi Rumah Sakit Bhayangkara Jambi tahun 2023.
Kajian Kualitatif Faktor Eksternal Yang Mempengaruhi Kehamilan Remaja di Kecamatan Indramayu Kabupaten Indramayu
Authors: Apriliani Purwandyarti , Aryanti Mira , Anggita Intan , Murni Dewi Eka Stia
Published: February 2024

Masa remaja merupakan periode terjadinya pertumbuhan dan perkembangan baik secara fisik, psikologis maupun intelektual. Keputusan yang diambil oleh remaja dalam menghadapi konflik bila tidak tepat, akan masuk kedalam perilaku berisiko dan harus menanggung dalam jangka pendek maupun jangka panjang didalam berbagai masalah kesehatan fisik dan psikososial. Tujuan Penelitian untuk menganalisis faktor eksternal yang dapat mempengaruhi kehamilan remaja Di Kecamatan Indramayu Kabupaten Indramayu. Penelitian Kualitatif menggunakan indepth interview (wawancara mendalam). Sampel yang digunakan ibu hamil remaja usia 11-19 tahun yang memenuhi kriteria inklusi dan tidak memenuhi kriteria eksklusi sebanyak 8 ibu hamil. Teknik pengambilan sample dengan purposive sampling. Waktu penelitian bulan November 2019-Januari 2020. hasil penelitian ini Faktor eksternal yang mempengaruhi kehamilan remaja di Kecamatan Indramayu Kabupaten Indramayu diantaranya faktor sosial dan budaya (stigma, perjodohan), faktor ekonomi, faktor lingkungan (kontrol keluarga dan prilaku seks pra nikah).
Campuran Infusa Talas (Xanthosoma Sagittifolium (L.) Schott), Kacang Kedelai (Glycine Max (L.) Merrill) Dan Ekstrak Ragi Sebagai Media Alternatif Pertumbuhan Bakteri Staphylococcus Aureus
Authors: Martsiningsih M. Atik , Suyana Suyana , Kasiyati Menik , Pudyastuti Rita Rena , Rahayu Muji , Ajzahra Alifia Ridha Aufa
Published: February 2024

Pada pertumbuhannya bakteri memerlukan media pertumbuhan yang harus memiliki kandungan nutrisi seperti karbohidrat, protein dan nitrogen. Media Nutrient Agar sering dimanfaatkan untuk melakukan penelitian atau pembelajaran namun, memiliki harga yang relatif tinggi dan banyak diproduksi oleh perusahaan asing. Sehingga dilakukan pemanfaatan bahan alami yang mudah didapat dan memiliki harga terjangkau seperti talas sebagai sumber karbohidrat, kacang kedelai sebagai sumber protein dan ekstrak ragi sebagai sumber nitrogen.Untuk mengetahui media campuran infusa talas (Xanthosoma sagittifolium (L.) Schott), kacang kedelai (Glycine max (L.) Merrill) dan ekstrak ragi dapat digunakan untuk menumbuhkan bakteri Staphylococcus aureus.Jenis penelitian ini adalah eksperimen murni (True Experimental Research) dengan desain penelitian Post-Test Only Control Group Design. Rerata jumlah koloni bakteri Staphylococcus aureus yang tumbuh pada media alternatif adalah 82104 CFU/ml dan pada media Nutrient Agar adalah 94104 CFU/ml. Rerata diameter koloni bakteri Staphylococcus aureus yang tumbuh pada media alternatif adalah 2,53 mm dan pada media Nutrient Agar adalah 2,66 mm. Selisih rerarata antara media alternatif dan media Nutrient Agar pada jumlah koloni dan diameter koloni sebesar -12104 CFU/ml (-12,74%) dan -0,13 mm (-4,75%). Media alternatif cukup efektif (87,26%) untuk pertumbuhan koloni bakteri dan efektif (95,25%) untuk perkembangbiakan koloni bakteri Staphylococcus aureus. Hasil statistik menunjukkan ada perbedaan jumlah koloni dan diameter koloni bakteri Staphylococcus aureus pada media alternatif, dalam arti pada jumlah koloni kurang subur dibandingkan dengan media Nutrient Agar dan pada diameter koloni sebanding dengan media Nutrient Agar.Media alternatif campuran infusa talas (Xanthosoma sagittifolium (L.) Schott), infusa kacang kedelai (Glycine max (L.) Merrill) dan ekstrak ragi dapat digunakan sebagai media alternatif pertumbuhan bakteri Staphylococcus aureus.
Analisis Asuhan Keperawatan Pada Agregat Anak Usia Sekolah Dasar Dengan Pendidikan Kesehatan Permainan Ular Tangga Untuk Meningkatkan Pengetahuan Jajanan Sehat
Authors: Afghani Apriliana , Wisanti Eka , Anggreny Yecy , Rukmini Endang Dwi
Published: February 2024

Pendidikan kesehatan jajanan sehat pada anak sangat dibutuhkan. Upaya meningkatkan pengetahuan jajanan sehat pada anak dapat melakukan pendidikan menggunakan media yang menarik seperti permainan ular tangga. Penerapan intervensi ini bertujuan untuk mengetahui efektifitas pendidikan kesehatan menggunakan media ular tangga terhadap pengetahuan jajanan sehat pada anak usia sekolah dasar. Hasil penelitian menunjukkan perbedaan rata-rata pengetahuan responden sebelum dilakukan intervensi (mean 9,17) meningkat menjadi (mean 17,25). Hasil uji paired t-test P value 0,001 (P value ? 0,05). Sehingga intervensi pendidikan kesehatan menggunakan permainan ular tangga memiliki efektifitas untuk meningkatkan pengetahuan jajajan sehat pada anak. Penelitian ini menyarankan agar pihak-pihak yang ingin melakukan pendidikan kesehatan kepada anak dapat menggunakan media permainan ular tangga sebagai salah satu media untuk meningkatkan pengetahuan pada anak.
Analisis Faktor Resiko Kejadian Miopia Pada Mahasiswa/i Program Studi Ilmu Komputer Universitas X Kota Medan Tahun 2023
Authors: Rahmi Amalia , Salsabila Fatma , Fatahillah Muhammad Abu , Khairiah Maulidia
Published: February 2024

Untuk melihat manusia membutuhkan mata sebagai indera penglihatan. Mahasiwa dengan segala akyivitasnya memerlukan penglihatan yang berfungsi dengan baik, namun berbagai aktivitas perkuliahan yang memanfaatkan teknologi dapat membuat mahasiswa beresiko lebih besar mengalami miopia. Tujuan penelitian ini yaitu untuk mengetahui apa saja faktor yang berhubungan dengan kejadian miopia pada mahasiswa/i program studi komputer, Universitas X. Penelititan ini menggunakan metode survei cepat dengan pendekatan cross sectional. Pengumpulan data menggunakan kuisioner via Google Form. Hasil penelitian ini adalah mahasiswa/i komputer di Universitas X mengalami miopia sebessar 55%, 55 orang memiliki riwayat keturunan,48 orang menggunakan komputer/gadget >5 jam, dan 72 orang menghabiskan waktu <1 Jam saat membaca buku. Terdapat hubungan yang signifikan antara riwayat keturunan (p value 0,006<0,05), durasi penggunaan komputer (p value 0,000<0,05) dengan kejadian miopia. Tidak ada hubungan yang signifikan antara jenis kelamin (p value 0,412>0,05), durasi membaca buku (p value 0,59>0,05) dengan kejadian miopia.
Pengaruh Massage Jahe Merah Terhadap Penurunan Intensitas Nyeri Osteoarthritis Lutut Pada Lansia
Authors: Rahmadeni Asfri Sri , Rishel Rika Astria
Published: February 2024

Elderly is a term used to describe a group of people who have reached the end of their lives and are experiencing a decline in their capacity to perform basic bodily functions, which can lead to a variety of health issues. One of them is the prevalence of joint disorders, which ranks third among various non-communicable diseases that affect the elderly (51.9 percent). The goal of this study was to see if red ginger massage could reduce pain intensity in elderly patients with knee osteoarthritis. The sample in this study was 6 senior persons, and it was an analytic study with a genuine experimental design and a pretest-posttest control group technique. The average amount before receiving red ginger massage was 2.80 in the treatment group and 2.87 in the control group, with the pain scale in both groups being the same in moderate discomfort. The aftereffects of a red ginger massage The average number in the treatment group was 1.87 on a mild pain scale, while the average number in the control group was 2.87 on a moderate pain scale because no therapy was given. In the intervention group, the paired T Test revealed a significant difference in the average value of pain reduction before and after delivering red ginger massage to the elderly, with p = 0.000 (p = 0.05). The elderly's discomfort was lessened after just one week of intervention. The elderly, it is hoped, will be able to do so in the future.
Hubungan Faktor yang Memengaruhi Indeks Prestasi Kumulatif dan Student Activities Performance System Mahasiswa Fakultas Kedokteran Universitas Andalas
Authors: Mahendika Devin , Chandra Multazam Fahreza , Julita Ema
Published: February 2024

This study aims to determine the relationship between factors that influence the cumulative grade point average and student activity performance system for Andalas University medical faculty students. This research is a categorical analytic study with a cross-sectional design. Sampling using simple random sampling technique to obtain 162 respondents. The research was conducted from February 2020-2021 on FK UNAND students class of 2016. The research data was obtained by filling out a questionnaire and guided interviews. The results showed that there was a significant relationship between entry, UKT, parental education, National Examination scores, and talent interest with GPA. In addition, there is no significant relationship between entry, UKT, parental education, National Exam scores and SAPS and there is a significant relationship between interest in talent and SAPS.
Kesiapsiagaan terhadap Bencana Banjir Studi Kualitatif di Dinas Kesehatan Kota Tanjungbalai Tahun 2022
Authors: Fawzi Eka Rizky , Ketaren Otniel , Sitorus Mido Ester
Published: February 2024

Kesiapsiagaan Dinas Kesehatan dalam upaya penanggulangan bencana banjir di Kota Tanjungbalai merupakan produktivitas Dinas Kesehatan pada tahap pra bencana. Penelitian ini bertujuan untuk mengetahui kesiapsiagaan Dinas Kesehatan Kota Tanjungbalai dalam menghadapi bencana banjir yang terjadi di Kota Tanjungbalai. Penelitian ini menggunakan pendekatan deskriptif kualitatif, dengan studi fenomenologi. Lokasi dan waktu analisis dilakukan di Dinas Kesehatan Kota Tanjungbalai pada bulan Januari hingga Agustus 2022. Hasil penelitian menunjukkan bahwa Dinas Kesehatan Kota Tanjungbalai belum siap karena beberapa hal berikut, yaitu secara kuantitas, jumlah sumber daya manusia di Dinas Kesehatan Kota Tanjungbalai sudah memadai dengan adanya Tim Gawat Darurat yang ditempatkan di setiap puskesmas namun tidak ada yang berlatar belakang pendidikan kebencanaan dan belum diberikan pelatihan serta belum adanya simulasi terkait kebencanaan, dan belum membuat kebijakan terkait kebencanaan serta pembuatan SOP dan MOU kerjasama lintas sektor terkait penanggulangan bencana. Sarana dan prasarana serta obat-obatan dan perbekalan masih belum memenuhi standar penanggulangan bencana. Perlu menjalin hubungan lintas sektoral dan komunikasi serta kerjasama lintas sektoral dengan instansi terkait serta perlu diadakan kegiatan pelatihan bersama dalam bentuk gladi dan simulasi agar siap dalam melaksanakan penanggulangan bencana banjir.
Pengembangan Sistem Informasi Ibu Hamil (SIBUMIL-PE) dalam Mendeteksi Kejadian Preeklampsia di Kabupaten Bangkalan
Authors: Nugraha Rivaldi Indra , Purnami Cahya Tri , Prasetijo Agung Budi , Wulandari Novita
Published: February 2024

Angka kematian ibu (AKI) hingga saat ini masih menjadi permasalahan utama di Kabupaten Bangkalan bahkan Indonesia, AKI salah satunya disebabkan karena terjadinya preeklamsia saat periode kehamilan. Penelitian ini bertujuan untuk melakukan pengembangan sistem informasi ibu hamil sebagai upaya deteksi dini kejadian preeklamsia di Kabupaten Bangkalan. Proses pengembangan sistem informasi metode pengembangan waterfall. Proses pengujian sistem informasi dilakukan menggunakan pengujian black-box. Subjek peneltian terdiri dari bidan yang melaksanakan praktek mandiri bidan (PMB) serta 1 orang bidan koordinator. Data kualitatif diperoleh dengan menggunakan wawancara dan brainstorming sebagai bahan analisis kebutuhan user. Hasil penelitian di proses dalam bentuk flowchart sistem, context diagram, data flow diagram, entity relationship diagram. Desain di proses kedalam bahasa pemrograman PHP dan dikombinasikan dengan database MySQL. Dari hasil penelitian tersebut sistem informasi memiliki beberapa fitur diantaranya; fitur login, fitur pencatatan ibu hamil, fitur admin, fitur home, fitur deteksi dini preeklampsia, fitur catatan hasil pemeriksaan ibu hamil dan fitur laporan.

Kata Kunci: Sistem Informasi, Deteksi Dini, Preeklamsia, Ibu Hamil
Hubungan antara Tingkat Pengetahuan dengan Perilaku Ibu Dalam Pencegahan Demam Berdarah Dengue
Authors: Sari Rita Kartika , Septiyani Resky , Mashoedi Imam Djamaluddin
Published: February 2024

Dengue Hemorrhagic Fever’s still a health problem in Indonesia, this is due to its increasing prevalence from year to year. Various obstacles can be found to reduce dengue cases, including the level of knowledge and behavior to prevent dengue. The objective of this research was to determine the relationship between the level of knowledge and the behavior of mothers in the prevention of DHF at the Genuk Public Health Center, Semarang. The research was conducted from August 2022 to September 2022. The type of research used was analytic observational with a cross-sectional approach, the number of samples used in this research was 126 samples of mothers who were taken by non-probability sampling with consecutive sampling, and the instrument used was a questionnaire with data analysis using Spearman rho. The results showed that from 126 samples, it was found that mothers who had a high level of knowledge 89.7% respondents, mothers with low knowledge levels 10.3% respondents, and mothers who had good preventive behavior towards dengue prevention were 74.6% of respondents, mothers with poor preventive behavior were 25.4%. Spearman rho test analysis obtained a p-value <0.05 (p = 0.001) so there was a relationship between the level of knowledge and the mother's behavior in preventing DHF, and the r value was 0.2-<0.4 (r = 0.283) with a weak relationship. The results of the bivariate analysis that there was a significant relationship between the variable level of knowledge and the behavior of mothers in preventing DHF.
Utilization of Green Spinach Juice In Making Rolled Omelet
Authors: Mahrani Indira Meutia , Eliska Eliska
Published: February 2024

Dadar roll is one of the traditional Indonesian snacks commonly found in traditional markets. Spinach contains lots of Vitamins A and C and a little Vitamin B. Spinach also contains important mineral salts such as calcium, phosphorus, and iron. The research method used is experimental research with the experimental design carried out is a Complete Randomized Design with 3 treatments. The highest average value is indicated by treatment C in terms of color, aroma, texture, and taste. Treatment C is made from rolled omelet with 100gr green spinach + 550cc water (600cc spinach juice). It can be implied that the best C treatment is preferred by the panelists. With an assessment in terms of color, treatment C is the most preferred sample with a mean value of 4.80. In terms of aroma, treatment C is the most preferred sample with a mean value of 4.56. In terms of texture, treatment C is the most preferred sample with a mean value of 4.24. And in terms of taste, treatment C is the most preferred sample with a mean value of 4.28.
Hubungan Pre dan Post Conference dengan Pendokumentasian Asuhan Keperawatan di Ruang Perawatan Cendana dan Akasia Rumah Sakit Dr. Bratanata Kota Jambi Tahun 2023
Authors: Komala Rossie Intan , Yusnilawati Yusnilawati , Kamariyah Kamariyah
Published: February 2024

Masalah yang sering muncul di lapangan dalam asuhan keperawatan adalah banyak perawat yang belum melakukan pendokumentasian keperawatan. Salah satu upaya untuk meningkatkan pelayanan asuhan keperawatan yang professional yaitu dengan pre dan post conference sebagai komunikasi perawat. Terlaksananya pre dan post conference dengan baik akan berdampak pada pendokumentasian asuhan keperawatan yang baik. Tujuan penelitian ini adalah untuk diketahuinya hubungan pre dan post conference dengan pendokumentasian asuhan keperawatan di ruang perawatan cendana dan akasia Rumah Sakit Dr. Bratanata Kota Jambi.. Penelitian ini merupakan penelitian kuantitatif dengan rancangan penelitian deskripsi korelasi dan pendekatan cross sectional. Jumlah sampel sebanyak 30 responden dengan teknik pengambilan sampel yaitu total sampling. Berdasarkan analisis data, pelaksanaan pre dan post conference terbanyak yaitu dalam kategori baik (96,7%), pendokumentasian asuhan keperawatan terbanyak berada dalam kategori lengkap (100%), dan berdasarkan hasil uji Chi-Square didapatkan nilai sig (2-tailed) yaitu 0,016 dan nilai korelasi 0,317. Terdapat hubungan yang bermakna antara pre dan post conference dengan pendokumentasian asuhan keperawatan di ruang perawatan cendana dan akasia Rumah Sakit Dr. Bratanata Kota Jambi Tahun 2023. Diharapkan penelitian ini dapat menjadi masukan sehingga perawat dapat memberikan asuhan keperawatan yang profesional.
Pengaruh Terapi Musik Klasik (Mozart) Terhadap Kemampuan Berbahasa Pada Anak Autisme di SLBN Prof.Sri.Soedewi.Masjchun Sofwan,S.H Kota Jambi
Authors: Ananda Fenni Dwi , Nasution Riska Amalya , Yuliana Yuliana
Published: February 2024

The prevalence of children with autism in Indonesia has reached 2.4 million in a few years. Children with autism have difficulties in growth and development, especially in language skills. Language ability is an important aspect that must be owned by everyone. There are various methods to assist in developing language skills, one of which is classical music therapy (Mozart). This study aims to determine the effect of classical music therapy (Mozart) on the language skills of children with autism at the SLBN Prof. Dr. Sri Soedewi Masjchun Sofwan, S.H. Jambi. This study uses a quantitative research type with a pre-experimental research design (pre-post test design with one group). The number of samples in this study was 10 respondents with a total sampling technique. Statistical test using paired-sample t-test. Results of statistical tests using Shapiro-Wilk, obtained p-value = 0.05 > ? 5%. There was an effect of giving classical music therapy (Mozart) where at the time of the pretest, it was found that the most respondents' language abilities were in the less category and after the post-test, the most respondents' language abilities were in the good category. There is a significant influence between giving classical music therapy (Mozart) on language skills in children with autism. It is hoped that parents or teachers can provide music therapy as an adjunct in fostering children with autism to improve language skills.
Pengaruh Terapi Bermain Storytelling (Bercerita) Terhadap Tingkat Nyeri Saat Prosedur Invasif Pada Anak Prasekolah di Rumah Sakit Dr. Bratanata Kota Jambi
Authors: Dewi Eza Reiskha , Ekawaty Fadliyana , Mutmainnah Muthia
Published: February 2024

Pendahuluan:Nyeri merupakan pengalaman sensori serta emosi yang tidak menyenangkan dan meningkat akibat adanya kerusakan jaringan yang aktual atau potensial serta yang dialami oleh anak. Salah satu terapi non farmakologis yang dapat di lakukan untuk mengatasi hal tersebut adalah dengan menggunakan terapi storytelling (bercerita). Tujuan dari penelitian ini adalah untuk mengetahui pengaruh terapi bermain storytelling (bercerita) terhadap tingkat nyeri saat prosedur invasif pada anak usia prasekolah di Rumah Sakit Dr. Bratanata Kota Jambi. Metode:Penelitian ini menggunakan desain penelitian Quasy Eksperimental dengan rancangan postest only with control group design. Populasi yang digunakan dalam penelitian ini adalah 36 anak usia 3-6 tahun. Pengambilan sampel dengan accidental sampling sejumlah 18 anak kelompok perlakuan dan 18 anak kelompok kontrol. Tingkat nyeri di ukur dengan wong beker faces pain rating scale. Analisis data menggunakan uji Mann-Withney. Hasil: Hasil uji analisis  Mann Withney didapatkan nilai p value 0,026 < 0,05 artinya ada perbedaan tingkat nyeri antara kelompok perlakuan dan kelompok kontrol. Kesimpulan: Ada pengaruh terapi bermain storytelling (bercerita) terhadap tingkat nyeri saat prosedur invasif pada anak usia prasekolah di Rumah Sakit Dr. Bratanata Kota Jambi. Oleh karena itu direkomendasikan bagi instansi dapat menerapkan terapi bermain dalam bentuk storytelling ini saat tindakan invasif pada anak usia prasekolah.
KEJADIAN STUNTING DAN FAKTOR RISIKO (Studi Kasus Kontrol pada Anak Balita di Wilayah Kerja Puskesmas Simarmata Kecamatan Simanindo Kabupaten Samosir Tahun 2022)
Authors: Damanik Harry M , Handini Myrnawati Crie , Ketaren Otniel , Sinaga Janno , Pane Masdalina
Published: February 2024

Studi Status Gizi Indonesia (SSGI) tahun 2021 melaporkan, Provinsi Sumatera Utara merupakan urutan 17 tertinggi prevalensi balita stunted dengan angka 25,8%. Prevalensi balita stunted di Kabupaten Samosir yaitu sebesar 28,4%. Penelitian ini merupakan penelitian analitik observasional dengan desain studi kasus-kontrol (case-control study). Adapun responden dalam penelitian ini adalah balita usia 0-59 bulan di wilayah kerja Puskesmas Simarmata dengan jumlah kelompok kasus sebanyak 40 responden dan kelompok kontrol sebanyak 80 responden. Uji Chi-Square menunjukkan ASI Ekslusif berpengaruh signifikan terhadap ¬stunting (p=0.02) OR=2.414 95%CI=1.091-5.341, tinggi badan ibu tidak berpengaruh signifikan terhadap stunting (p=0.76) OR=0.231 95%CI=0.040-1.318, BBLR berpengaruh signifikan terhadap stunting (p=0.002) OR=0.072 95%CI=0.008-0.619, jarak kelahiran tidak berpengaruh signifikan terhadap stunting (p=1.0) OR=1.0 95%CI=0.317-3.151. ASI Ekslusif dan BBLR berpengaruh secara signifikan terhadap kejadian stunting. Hasil uji regresi logistik ganda menunjukkan faktor risiko paling dominan terjadinya stunting di Wilayah Kerja Puskesmas Simarmata adalah BBLR, dimana anak dengan riwayat berat badan rendah mempunyai risiko terkena stunting 43 kali dibanding anak yang tidak riwayat berat badan lahir rendah. (p=0.003) OR=43.00 95%CI=3.563-519.05. Puskesmas Simarmata telah membuat program pencegahan dan penurunan angka kejadian Stunting berupa deteksi dini ibu hamil dengan Kurang Energi Kronik (KEK), Pengawaasan pemberian makan tambahan (PMT) pada ibu hamil yang mengalami KEK, melakukan edukasi kepada ibu hamil dan ibu menyusui tentang cara mengolahan makanan protein tinggi.
Wanita 74 Tahun Dengan Metastasis Pada Lobus Parieto-Oksipital Pada Melanoma Maligna
Authors: Titanic Pussof Yayazucah , Timotius Timotius , Johansen Johansen , Kentanto Given , Priyanto Teguh
Published: February 2024

Melanoma is a tumor that is produced by the malignant transformation of melanocyte cells. Melanoma is the leading cause of premature death from cancer. Known risk factors include personal or family history of melanoma, large numbers of naevi and/or dysplastic naevi, congenital melanocytic naevi, sun-damaged skin, history of non-melanoma skin cancer, and immunodeficiency. Based on the Basic Health Research Results (Riskesdas) report, skin cancer as a whole ranks 3rd in Indonesia. Epidemiological studies of skin cancer have reported in Jakarta in 2014–2017, where out of 263 cases of skin cancer, malignant melanoma ranks third with the highest incidence of skin cancer (5.7%). Diagnosis of melanoma can be made by assessing the skin lesions with the naked eye and also by the patient's clinical symptoms. A person's risk of metastases is directly related to the depth of invasion and ulceration of their primary lesion. Among solid tumors, melanoma has one of the highest propensities to cause brain metastases with a proportion of more than 25% of patients. Although the current cancer treatment paradigm may reflect a combination of surgery, chemotherapy, radiotherapy, and immunotherapy with medical management, options for the treatment of metastatic brain cancer remain limited.
Hubungan Self Care dengan Quality of Life Pasien Diabetes Melitus Tipe II di Ruang Bedah dan Interna Rsud Undata Palu Provinsi Sulawesi Tengah
Authors: Butudoka Ilham Y , Rammang Sisilia , Kadang Yulta
Published: February 2024

Diabetes Melitus adalah salah satu penyakit mematikan di dunia yang mana menyebabkan penurunan Quality of Life sehingga memerlukan perawatan yang tepat disebut Self Care. Self Care merupakan aktivitas dari individu dalam melakukan perawatan diri sendiri. Penelitian ini bertujuan mengetahui hubungan Self Care dengan Quality of Life pasien Dabetes melitus tipe II. Penelitian ini menggunakan metode penelitian kuantitatif analitik dengan rancangan penelitian cross sectional. Teknik pengambilan sampel menggunakan porpusive sampiling dengan jumlah sampel sebanyak 55 pasien. Pengumpulan data menggunakan kuesioner Summary of Diabetes Self Care (SDSCA) dan Diabetes Quality of Life (DQOL). Hasil penelitian ini menggunakan uji Chi-Square, diperoleh nilai p = 0,000 (p =<0,005). Kesimpulan dari penelitian ini adalah terdapat hubungan Self Care dengan Quality of Life pasien Diabetes Melitus tipe II yang diharapkan dapat meningkatkan status kesehatan dan mencegah terjadinya komplikasi lebih lanjut. Hasil penelitian ini dapat digunakan sebagai informasi dan pengetahuan tentang Self Care dengan meningkatkan Quality of Life  penderita Diabeted Melitus dengan cara menjaga pola makan, olahraga dan melakukan aktivitas fisik yang teratur sehingga dapat menjalankan kehidupan secara normal.