bluuebunny/crossref_metadata_2025 huggingface dataset:
Establishment and validation of PTE prediction model in patients with cerebral contusion
Authors: Lin Shengwu , Wang Qianqian , Zhu Yufeng , Jin Xiaoqing , Han Pei , Lu Zhongsheng
Published: November 2022

Post-traumatic epilepsy (PTE) is an important cause of poor prognosis in patients with cerebral contusions. The primary purpose of this study is to evaluate the high-risk factors of PTE by summarizing and analyzing the baseline data, laboratory examination, and imaging features of patients with a cerebral contusion, and then developing a Nomogram prediction model and validating it. This study included 457 patients diagnosed with cerebral contusion who met the inclusion criteria from November 2016 to November 2019 at the Qinghai Provincial People's Hospital. All patients were assessed for seizure activity seven days after injury. Univariate analysis was used to determine the risk factors for PTE. Significant risk factors in univariate analysis were selected for binary logistic regression analysis. P < 0.05 was statistically significant. Based on the binary logistic regression analysis results, the prediction scoring system of PTE is established by Nomogram, and the line chart model is drawn. Finally, external validation was performed on 457 participants to assess its performance. Univariate and binary logistic regression analyses were performed using SPSS software, and the independent predictors significantly associated with PTE were screened as Contusion site, Chronic alcohol use, Contusion volume, Skull fracture, Subdural hematoma (SDH), Glasgow coma scale (GCS) score, and Non late post-traumatic seizure (Non-LPTS). Based on this, a Nomogram model was developed. The prediction accuracy of our scoring system was C-index = 98.29%. The confidence interval of the C-index was 97.28% ~ 99.30%. Internal validation showed that the calibration plot of this model was close to the ideal line. This study developed and verified a highly accurate Nomogram model, which can be used to individualize PTE prediction in patients with a cerebral contusion. It can identify individuals at high risk of PTE and help us pay attention to prevention in advance. The model has a low cost and is easy to be popularized in the clinic. This model still has some limitations and deficiencies, which need to be verified and improved by future large-sample and multicenter prospective studies.
Application of Bayesian networks to identify factors influencing acceptability of HIV pre-exposure prophylaxis in Guilin, China
Authors: Zhou Lingmi , Shi Wuxiang , Assanangkornchai Sawitri , Vichitkunakorn Panupong , Tang Jie
Published: November 2022

Pre-exposure prophylaxis (PrEP) is an effective strategy to prevent uninfected individuals from contracting human immunodeficiency virus (HIV), however it must be acceptable to stakeholders in order to be effective. This study aimed to assess the acceptability of PrEP and related influencing factors. A cross-sectional survey was conducted among female sex workers (FSW), people who inject drugs (PWID), and men who have sex with men (MSM) using respondent driven sampling. Factors influencing PrEP acceptability were estimated using ordinal logistic regression and Bayesian networks. The survey included 765 eligible participants. The mean score of the perceived acceptability index was 3.9 (SD = 1.97). Multivariable logistic regression analysis revealed a higher acceptance of PrEP was associated with elder age, having other medical insurance, higher perceived utility of PrEP in facilitating prevention of HIV, higher perceived ease of use, higher perceived risk of increased risk behavior, higher perceived privacy problem in using PrEP, higher perceived comparative advantage over condom use, higher perceived comparative advantage of having sex when the urge arises, and higher perceived image of PrEP user as having sexual risky behavior, as public-minded and as health-conscious. The Bayesian network model showed perceived ease of use, perceived image of user as health-conscious, and perceived comparative advantage of having sex when the urge arises were directly associated with acceptability of PrEP. If these three factors were at a high level, 74.6% of the participants would have a high level of acceptability of PrEP. Effective education strategies to promote the acceptance of PrEP are needed. Implementation strategies should incorporate more inclusive messaging and build positive publicity for PrEP to reduce the stigma that PrEP use indicates risky behavior.
Zn(II) binding to pramlintide results in a structural kink, fibril formation and antifungal activity
Authors: Dudek Dorota , Dzień Emilia , Wątły Joanna , Matera-Witkiewicz Agnieszka , Mikołajczyk Aleksandra , Hajda Agata , Olesiak-Bańska Joanna , Rowińska-Żyrek Magdalena
Published: November 2022

The antimicrobial properties of amylin, a 37-amino acid peptide hormone, co-secreted with insulin from the pancreas, are far less known than its antidiabetic function. We provide insight into the bioinorganic chemistry of amylin analogues, showing that the coordination of zinc(II) enhances the antifungal properties of pramlintide, a non-fibrillating therapeutic analogue of amylin. Zinc binds to the N-terminal amino group and His18 imidazole, inducing a kink in the peptide structure, which, in turn, triggers a fibrillization process of the complex, resulting in an amyloid structure most likely responsible for the disruption of the fungal cell.
Sensitive and rapid detection of Babesia species in dogs by recombinase polymerase amplification with lateral flow dipstick (RPA-LFD)
Authors: Onchan Warunya , Ritbamrung Onchira , Changtor Phanupong , Pradit Waranee , Chomdej Siriwadee , Nganvongpanit Korakot , Siengdee Puntita , Suyasunanont Urasri , Buddhachat Kittisak
Published: November 2022

Canine babesiosis is a tick-borne disease caused byBabesiaspp., which infects and destroys healthy erythrocytes, leading to mortality and morbidity in dogs. The diagnosis of babesiosis is tedious and time-consuming, especially in latent and chronic infections. Here, a recombinase polymerase amplification combined with a lateral flow dipstick (RPA-LFD) assay was developed for rapid and accurate detection ofBabesiaspp. in canine blood specimens based on the 18S rRNA region. The RPA-LFD assay using rpaBab264 gave specificity toBabesiaspp. in dogs (B. vogeliandB. gibsoni) without cross-amplification to other parasites (apicomplexans and non-apicomplexans), with detection limit of at least 22.5 copies/μl (0.1 fg/µl) at 40 °C for at least 10 min. The whole process of DNA amplification by RPA and readout by LFD did not exceed 30 min. To determine the performance of the RPA-LFD assay, a total of 30 clinical samples was examined and compared with conventional PCR (cPCR) and multiplex HRM (mHRM). Eight dogs (26.67%) were detected as positive by RPA-LFD, while seven and six were found positive by cPCR and mHRM, respectively. RPA-LFD and cPCR showed high agreement withBabesiaspp. detection with kappa > 0.9. We confirmed that the dogs were infected byB. vogelifrom sequences of positive PCR results. Our findings suggested that RPA-LFD using the rpaBab264 assay offered a rapid, accurate, cost-effective and simple method forBabesiaspp. detection that is feasibly applicable to be rapid kit at a pet hospital or point-of-care testing.
Effectiveness of cone-beam computed tomography-generated cephalograms using artificial intelligence cephalometric analysis
Authors: Chung Eun-Ji , Yang Byoung-Eun , Park In-Young , Yi Sangmin , On Sung-Woon , Kim Young-Hee , Kang Sam-Hee , Byun Soo-Hwan
Published: November 2022

Lateral cephalograms and related analysis constitute representative methods for orthodontic treatment. However, since conventional cephalometric radiographs display a three-dimensional structure on a two-dimensional plane, inaccuracies may be produced when quantitative evaluation is required. Cone-beam computed tomography (CBCT) has minimal image distortion, and important parts can be observed without overlapping. It provides a high-resolution three-dimensional image at a relatively low dose and cost, but still shows a higher dose than a lateral cephalogram. It is especially true for children who are more susceptible to radiation doses and often have difficult diagnoses. A conventional lateral cephalometric radiograph can be obtained by reconstructing the Digital Imaging and Communications in Medicine data obtained from CBCT. This study evaluated the applicability and consistency of lateral cephalograms generated by CBCT using an artificial intelligence analysis program. Group I comprised conventional lateral cephalometric radiographs, group II comprised lateral cephalometric radiographs generated from CBCT using OnDemand 3D, and group III comprised lateral cephalometric radiographs generated from CBCT using Invivo5. All measurements in the three groups showed non-significant results. Therefore, a CBCT scan and artificial intelligence programs are efficient means when performing orthodontic analysis on pediatric or orthodontic patients for orthodontic diagnosis and planning.
Dynamic cardiac computed tomography characteristics of double-chambered right ventricle
Authors: Chang Monal Yu-Hsuan , Liou Yan-De , Huang Jou-Hsuan , Su Chia-Hung , Huang Shu-Chien , Lin Ming-Tai , Chen Shyh-Jye
Published: November 2022

To introduce image characteristics of double-chambered right ventricle on cardiac computed tomography and set a diagnostic criterion for the diagnosis. We retrospectively collected and measured the right ventricular constrictive ratio on computed tomography images in children who had simple ventricular septal defects in the past 10 years, because double-chambered right ventricle is often associated with ventricular septal defects. The right ventricular constrictive ratio was defined as the subinfundibular cross-sectional intraluminal area during end-systole divided by the area during end-diastole in the same patient. We compared the right ventricular constrictive ratio between subjects with concomitant double-chambered right ventricle and those without. 52 children were included, and 23 (44.2%) of them have concomitant double-chambered right ventricle. In most cases (n = 21; 91.3%), the hypertrophied muscular bundles occur just inferior to the level of the supraventricular crest in the right ventricle. Mean right ventricular constrictive ratio in patients with double-chambered right ventricle (15%) was significantly smaller than that without (29%). A cut-off value of a right ventricular constrictive ratio less than 20.1% was established to diagnose double-chambered right ventricle with an 89.7% sensitivity and 78. 3% specificity. Right ventricular constrictive ratio can be a valuable asset for the preoperative diagnosis of double-chambered right ventricle with cardiac computed tomography.
The evolution of plant proton pump regulation via the R domain may have facilitated plant terrestrialization
Authors: Stéger Anett , Hayashi Maki , Lauritzen Emil Wacenius , Herburger Klaus , Shabala Lana , Wang Cuiwei , Bendtsen Amalie Kofoed , Nørrevang Anton Frisgaard , Madriz-Ordeñana Kenneth , Ren Shichao , Trinh Mai Duy Luu , Thordal‑Christensen Hans , Fuglsang Anja Thoe , Shabala Sergey , Østerberg Jeppe Thulin , Palmgren Michael
Published: November 2022

Plasma membrane (PM) H+-ATPases are the electrogenic proton pumps that export H+ from plant and fungal cells to acidify the surroundings and generate a membrane potential. Plant PM H+-ATPases are equipped with a C‑terminal autoinhibitory regulatory (R) domain of about 100 amino acid residues, which could not be identified in the PM H+-ATPases of green algae but appeared fully developed in immediate streptophyte algal predecessors of land plants. To explore the physiological significance of this domain, we created in vivo C-terminal truncations of autoinhibited PM H+‑ATPase2 (AHA2), one of the two major isoforms in the land plant Arabidopsis thaliana. As more residues were deleted, the mutant plants became progressively more efficient in proton extrusion, concomitant with increased expansion growth and nutrient uptake. However, as the hyperactivated AHA2 also contributed to stomatal pore opening, which provides an exit pathway for water and an entrance pathway for pests, the mutant plants were more susceptible to biotic and abiotic stresses, pathogen invasion and water loss, respectively. Taken together, our results demonstrate that pump regulation through the R domain is crucial for land plant fitness and by controlling growth and nutrient uptake might have been necessary already for the successful water-to-land transition of plants.
Stable and unstable capillary fingering in porous media with a gradient in grain size
Authors: Vincent-Dospital Tom , Moura Marcel , Toussaint Renaud , Måløy Knut Jørgen
Published: November 2022

Multiphase flows in complex porous networks occur in many natural processes and engineering applications. We present an analytical, experimental and numerical investigation of slow drainage in porous media that exhibit a gradient in grain size. We show that the effect of such structural gradient is similar to that of an external force field on the obtained drainage patterns, when it either stabilises or destabilises the invasion front. For instance, gravity can enhance or reverse the drainage pattern in graded porous media. In particular, we show that the width of stable drainage fronts scales both with the spatial gradient of the necessary pressure for pore invasion and with the local distribution of this (disordered) threshold. The scaling exponent results from percolation theory and is − 0.57 for 2D systems. Overall, introducing a dimensionless Fluctuation number, we propose a unifying theory for the up-scaling of dual immiscible fluid flows covering most classical scenarii.
Feasibility of gasifying mixed plastic waste for hydrogen production and carbon capture and storage
Authors: Lan Kai , Yao Yuan
Published: November 2022

Waste plastic gasification for hydrogen production combined with carbon capture and storage is one technology option to address the plastic waste challenge. Here, we conducted a techno-economic analysis and life cycle assessment to assess this option. The minimum hydrogen selling price of a 2000 oven-dry metric ton/day mixed plastic waste plant with carbon capture and storage is US$2.26–2.94 kg−1 hydrogen, which can compete with fossil fuel hydrogen with carbon capture and storage (US$1.21–2.62 kg−1 hydrogen) and current electrolysis hydrogen (US$3.20–7.70 kg−1 hydrogen). An improvement analysis outlines the roadmap for reducing the average minimum hydrogen selling price from US$2.60 to US$1.46 kg−1 hydrogen, which can be further lowered to US$1.06 kg−1 hydrogen if carbon credits are close to the carbon capture and storage costs along with low feedstock cost. The life cycle assessment results show that hydrogen derived from mixed plastic waste has lower environmental impacts than single-stream plastics.
Multi-element stable isotope Raman microspectroscopy of bacterial carotenoids unravels rare signal shift patterns and single-cell phenotypic heterogeneity
Authors: Weng Julian , Müller Kara , Morgaienko Oleksii , Elsner Martin , Ivleva Natalia P.
Published: November 2022

Investigation of bacteria with D-carotenoids reveals unique Raman signatures, inclusive unexpected blue-shift. Simultaneous monitoring of 13C & D of carotenoids provides complementary information on cell growth and metabolic activity, respectively.
Two-dimensional Be2Al and Be2Ga monolayer: anti-van’t Hoff/Le Bel planar hexacoordinate bonding and superconductivity
Authors: Li Hai-xia , Wang Meng-hui , Li Quan , Cui Zhong-hua
Published: November 2022

A 2D superconductor, named Be2Al and Be2Ga monolayer, containing anti-van’t Hoff/Le Bel planar hexacoordinate Be and Al/Ga bonding was theoretically designed.
Piezoelectric ferromagnetism in Janus monolayer YBrI: a first-principles prediction
Authors: Guo San-Dong , Wang Meng-Xia , Tao Yu-Ling , Liu Bang-Gui
Published: November 2022

Coexistence of intrinsic ferromagnetism and piezoelectricity, namely piezoelectric ferromagnetism (PFM), is crucial to advance multifunctional spintronic technologies.
Collaborative methods to enhance reproducibility and accelerate discovery
Authors: Leins Drew A. , Haase Steven B. , Eslami Mohammed , Schrier Joshua , Freeman Jared T.
Published: November 2022

The discoveries that will advance science in profound ways will be made possible by collaborative, multidisciplinary efforts. These efforts require practices and incentives for sharing methods and data, and for leveraging complementary capabilities.
An investigation of the effects of ZnO inverse opal pore size in the composite of ZnO nanorods/ZnO inverse opal on the performance of quantum dot-sensitized solar cells
Authors: Wang Zi , Liu Yuyu , Li Linjie , Gao Shufang , Zhu Desheng , Yu Xiangxiang , Cheng Shubo , Zheng Dingshan , Xiong Yan
Published: November 2022

A semiconductor oxide composite consisting of ZnO nanorods and ZnO inverse opal (IO) was fabricated and used in the photoanode of QDSSCs, and the effects of ZnO IO pore size in the composite on the performance of the QDSSCs were investigated.
Covalent conjugation of proteins onto fluorescent single-walled carbon nanotubes for biological and medical applications
Authors: Wang Hanxuan , Boghossian Ardemis A.
Published: November 2022

Recent advances enable new chemical strategies for covalent protein linking to single-walled carbon nanotubes.
Facile preparation of amorphous photonic structure towards rapid temperature sensing and antibacterial textile
Authors: Ji Yun-Liang , Gao Lan-Xing , Tian Yu
Published: November 2022

A rapid temperature sensing device and antibacterial textiles were successfully developed based on amorphous photonic crystals with bright structural colors which were doped with silver nanoparticles to absorb incoherently scattered light.
Metal nanoparticle-decorated germanane for selective photocatalytic aerobic oxidation of benzyl alcohol
Authors: Ni Chuyi , Chevalier Madison , Veinot Jonathan G. C.
Published: November 2022

The metal nanoparticle (Au, Ag, Cu, Pd, Pt) decorated germanane (M@GeNSs) were prepared via in situ reduction of the metal ions and explored as photocatalysts for selective visible light-induced oxidation of benzyl alcohol to benzaldehyde.
Ultrasmall porphyrin-silica core–shell dots for enhanced fluorescence imaging-guided cancer photodynamic therapy
Authors: Hameed Sadaf , Bhattarai Pravin , Gong Zhuoran , Liang Xiaolong , Yue Xiuli , Dai Zhifei
Published: November 2022

Ultrasmall hydrophilic PSDs combined with excellent imaging-guided therapeutic abilities and renal clearance behavior represent a promising platform for cancer imaging and therapy.
Broadband reflection in polymer-stabilized cholesteric liquid crystalsviaspin-coating MoO2nanoparticles
Authors: Zhao Yuzhen , Li Chaonian , Lang Tingting , Li Jinqian , Guo Zhun , Yao Ruijuan , Gao Jianjing , Zhao Yang , Wang Dong
Published: November 2022

The SEM image of the polymer network of samples e1–e5: (e1) 4.8% C6M; (e2) 6.8% C6M; (e3) 8.8% C6M; (e4) 10.8% C6M; (e5) 12.8% C6M; and (e4′) cross-sectional image of e4.
Bimetal chloride catalyzed hydrogenation of silicon tetrachloride in the presence of silicon
Authors: Ji Yuwen , Wang Huhu , Jia Zhaohang , Peng Wencai , Zhang Jinli , Zhang Jianshu
Published: November 2022

Due to the better dispersion and formation of more copper silicides, the catalytic performance of bimetallic chlorides was significantly improved.
Correction: Ln-MOFs with window-shaped channels based on triazine tricarboxylic acid as a linker for the highly efficient capture of cationic dyes and iodine
Authors: Zhao Yue , Zhang Na , Wang Ying , Bai Feng Ying , Xing Yong Heng , Sun Li Xian
Published: November 2022

Correction for ‘Ln-MOFs with window-shaped channels based on triazine tricarboxylic acid as a linker for the highly efficient capture of cationic dyes and iodine’ by Yue Zhao et al., Inorg. Chem. Front., 2021, 8, 1736–1746, https://doi.org/10.1039/d0qi01279c.
A Schiff base complex of lanthanum on modified MCM-41 as a reusable nanocatalyst in the homoselective synthesis of 5-substituted 1H-tetrazoles
Authors: Tahmasbi Bahman , Nikoorazm Mohsen , Moradi Parisa , Abbasi Tyula Yunes
Published: November 2022

In this work, mesoporous MCM-41 was modified by a new Schiff-base formed from the condensation of triethylenetatramine and 5-bromosalicylaldehyde. Then, lanthanum was immobilized on its surface as reusable nanocatalyst in the synthesis of tetrazoles.
Recent advances in thin film nanocomposite membranes containing an interlayer (TFNi): fabrication, applications, characterization and perspectives
Authors: Wang Jiaqi , Wang Lei , He Miaolu , Wang Xudong , Lv Yongtao , Huang Danxi , Wang Jin , Miao Rui , Nie Lujie , Hao Jiajin , Wang Jianmin
Published: November 2022

Polyamide (PA) reverse osmosis and nanofiltration membranes have been applied widely for desalination and wastewater reuse in the last 5–10 years.
Topological defects and nanoholes in graphene oxide/hexagonal boron nitride heterostructures: stress buildup and accumulation
Authors: Fan Lei , Cai Xinyu , Wang Hongwei , Ye Jian , Feng Yong , Huang Zhuye , Qu Chen
Published: November 2022

The built-in distorted stress field of graphene (Gr) and its derivatives in defective state will induce local geometrical buckling due to the geometry of monatomic layer.
Correction: Construction of isostructural hydrogen-bonded organic frameworks: limitations and possibilities of pore expansion
Authors: Suzuki Yuto , Gutiérrez Mario , Tanaka Senri , Gomez Eduardo , Tohnai Norimitsu , Yasuda Nobuhiro , Matubayasi Nobuyuki , Douhal Abderrazzak , Hisaki Ichiro
Published: November 2022

Correction for ‘Construction of isostructural hydrogen-bonded organic frameworks: limitations and possibilities of pore expansion’ by Yuto Suzuki et al., Chem. Sci., 2021, 12, 9607–9618, https://doi.org/10.1039/D1SC02690A.
A label-free silicon-based spherical nucleic acid enzyme (SNAzyme) for ultrasensitive chemiluminescence detection of acute myocardial infarction-related nucleic acids
Authors: Qu Shiyang , Shi Lin , Li Huan , Li Tao
Published: November 2022

Compared with Au@SNAzyme, SiO2–SNAzyme@ABEI higher catalytic activity, which can be applied chemiluminescence detection of miDNA-499.
Achieving 31% efficiency in organic photovoltaic cells under indoor light using a low energetic disorder polymer donor
Authors: Bi Pengqing , An Cunbin , Zhang Tao , Chen Zhihao , Xu Ye , Cui Yong , Wang Jianqiu , Li Jiayao , Wang Yafei , Ren Junzhen , Hao Xiaotao , Zhang Shaoqing , Hou Jianhui
Published: November 2022

A series of wide bandgap terpolymers are designed and synthesized, which exhibit low energetic disorders. Based on the terpolymers, outstanding PCEs of over 31% (1000 lux) for an indoor OPV cell and over 18.2% (one-sun) for an OPV cell are achieved.
One-dimensional confined p–n junction Co3S4/MoS2 interface nanorods significantly enhance polysulfide redox kinetics for Li–S batteries
Authors: Zhou Wei , Ning Shunlian , Fan Bin , Wu Qikai , Mi Luo , Zhao Dengke , Zhou Kai , Wang Nan
Published: November 2022

Exploring MoS2-based sulfur hosts with high performance is an effective strategy for promoting the extensive application of Li–S batteries.
Biomimetic dual-responsive bioengineered nanotheranostics for intracellular cascade-synthesizing chemo-drugs and efficient oncotherapy
Authors: Zhang Xin , Zhu Xinglin , He Yuan , Zhang Ying , Huang Shan , Yi Xue , Li Ying , Hou Zhenqing , Fan Zhongxiong
Published: November 2022

Intracellular-synthesized chemo-drugs based on the inherent characteristics of the tumor microenvironment (TME) have been extensively applied in oncotherapy.
Inorganic ferroelectric thin films and their composites for flexible electronic and energy device applications: current progress and perspectives
Authors: Jayakrishnan Ampattu R. , Kumar Anuj , Druvakumar Sahana , John Rosmin , Sudeesh Meera , Puli Venkata Sreenivas , Silva José P. B. , Gomes Maria J. M. , Sekhar Koppole C.
Published: November 2022

Inorganic ferroelectric thin films and their composites with unique physical properties have motivated extensive research work and achieved substantial advances for flexible electronic and energy device applications.
Kinetic and isotherm studies on the adsorption–desorption of technical-grade endosulfan in loamy soils under Theobroma cacao L cultivation, Southwestern Nigeria
Authors: Vaikosen Edebi N. , Davidson Christine M. , Olu-Owolabi Bamidele I. , Gibson Lorraine T. , Agunbiade Foluso O. , Kashimawo Adesegun J. , Adebowale Kayode O.
Published: November 2022

Fate of technical endosulfan in T. cacao L farm soils was studied using the OECD batch model. Rate constants for α- and β-isomers ranged from 6.91 × 10−3 to 2.85 × 10−4 min−1. Pesticide was leachable. TOM/clay could be used as mitigants for its mobility.
Two reference vector sets based evolutionary algorithm for many‐objective optimization
Authors: Qin Cifeng , Ming Fei , Gong Wenyin
Published: November 2022

Solving many‐objective optimization problems (MaOPs) by means of evolutionary algorithms obtains considerable attention in the community of evolutionary computation. However, it is a difficult task to effectively handle MaOPs with both regular and irregular Pareto front (PF) shapes. In this paper, a novel two reference vector sets based evolutionary algorithm, referred to as TVEA, is proposed to solve both types of MaOPs. TVEA can be featured as i) two independent reference vector sets are used, where the regular reference vector set is used for the regular PF MaOPs and the irregular one is used for the irregular PF MaOPs; ii) according to the two reference vector sets, TVEA automatically detects the PF shape of a MaOP at hand; iii) a new delete‐and‐add strategy is proposed to adaptively update the irregular reference vector set; iv) a novel environmental selection strategy is developed to handle the irregular PF MaOPs. TVEA is extensively evaluated on 23 benchmark MaOPs with both regular and irregular PF shapes. The results indicate that TVEA can correctly detect the PF shape of MaOPs to be solved. Compared with other state‐of‐the‐art algorithms, TVEA obtains better or at least competitive results on both types of MaOPs.
Anti‐forensics for double JPEG compression based on deep reinforcement learning
Authors: Tang Weixuan , Huang Dequ , Li Bin
Published: November 2022

DJPEG (double JPEG compression) detection has received attention in image forensics. In order to study the limitations of forensics detectors under attacks, it is essential to develop DJPEG anti‐forensics techniques. Compared with anti‐forensics operations performed in spatial domain, existing DCT‐based methods have not brought their potential to full play due to the difficulty of directly manipulating DCT coefficients. In recent years, DRL (deep reinforcement learning) has developed rapidly in image‐related tasks. Its ability of decision making can turn an unpredictable restoration step into multiple simple trial‐and‐error modification steps. In this paper, it is investigated how to efficiently modify DCT coefficients for anti‐forensics purpose with the help of DRL, and propose a method called AFDJ‐DRL (Anti‐forensics Framework for DJPEG based on DRL). Specifically, an agent utilizes a policy network to extract DCT inter‐block and intra‐block features and learn a coefficient‐level policy. An environment assigns rewards from multiple sources. Via maximizing such rewards, the agent can learn to modify DCT coefficients in several rounds to obtain images with anti‐forensics capability. Experimental results show that the AFDJ‐DRL is superior to existing DCT‐based methods, and can be applied as a post‐processing step for spatial ones for further performance improvement.
Global kinematics study of OH masers in W49N
Authors: Mendoza-Torres J. E. , Juárez-Gama M. , Rodríguez-Esnard I. T.
Published: November 2022

Context. Star formation is underway in the W49N molecular cloud (MC) at a high level of efficiency, with almost twenty ultra-compact (UC) HII regions observed thus far, indicating a recent formation of massive stars. Previous works have suggested that this cloud is undergoing a global contraction.

Aims. We analyse the data on OH masers in the molecular cloud W49N, observed with the VLBA at the 1612, 1665, and 1667 MHz transitions in left circular polarization (LCP) and right circular polarization (RCP) with an aim to study the global kinematics of the masers.

Methods. We carried out our study based on the locations and observed velocities of the maser spots, Vobs. We found the location (α, δ)m of the maximum correlation between V = Vobs−Vsys (with Vsys the systemic velocity) and distance to it. The velocities were fitted to the straight line of Vobs−Vsys versus d(α,δ)m, resulting in Vftd. The difference between the fitted values and those obtained from observations is ∆ V = (Vobs−Vsys)-Vftd. The Vobs−Vsys velocity shows a gradient as a function of the distance to (α, δ)m, where the closer spots have the largest velocities. Spots with similar velocities are located in different sectors, with respect to (α, δ)m. Then, we assumed that the spots are moving towards a contraction centre (CCOH), which is at the apex of a CONUS. We also assumed that the distance of each spot to CCOH is dcc = √2 d(α,δ)m and that they fall with a velocity Vcc = √2Vftd, with the total velocity being VTot = Vcc + √2 Δ V. Using this velocity, we estimated the free-fall velocity.

Results. The coordinates of (α, δ)m are effectively (α2000 = 19:10:13.1253, δ2000 = 9:6:13.570). The observed dispersion with respect to the global trend against dcc, shows a maximum at 0.12 pc, with a decay from 0.12 to 0.19 pc, which is faster than that taking place between 0.19 and 0.42 pc. Based on VTot, an inner mass of Minn = 2500 M⊙ was estimated. In addition, the estimated accretion rate is Ṁ = 1.4×10−3 M⊙yr−1, which requires a time of tinn = 1.8×106 yr to accumulate Minn. The free-fall time, assuming n = 1×10−4 cm−3, is tff = 3.4×105 yr. Performing the same procedure with published data that are of lower spatial resolution (than the VLBA data) produces similar results. For example, based on the available data, we find that (α, δ)m = (19:10:13.1392, 9:6:13.4387) J2000, which is at ≲ 0.3 asec from what has been calculated with the VLBA data, with an estimated inner mass of 2700 M⊙. A sub-collapse appears to be taking place in the region traced by the OH maser spots. Based on methanol maser cloudlets data, which lie in a smaller region, another possible centre of contraction is identified, which could be due to a sub-collapse towards a 75 M⊙ inner mass.

Conclusions. The velocities of the OH spots at W49N, along with their positions with respect to (α, δ)m, make it possible to trace a global kinematics that is apparently due to a sub-collapse in the W49N MC.
Uniform boundedness for the optimal controls of a discontinuous, non-convex Bolza problem,
Authors: Bettiol Piernicola , Mariconda Carlo
Published: November 2022

We consider a Bolza type optimal control problem of the form

[see formula in PDF]

Subject to:

[see formula in PDF]

where Λ(s, y, u) is locally Lipschitz in s, just Borel in (y, u), b has at most a linear growth and both the Lagrangian Λ and the end-point cost function g may take the value +∞. If b ≡ 1, g ≡ 0, (Pt, x) is the classical problem of the Calculus of Variations. We suppose the validity of a slow growth condition in u, introduced by Clarke in 1993, including Lagrangians of the type
[see formula in PDF] and [see formula in PDF] and the superlinear case. We show that, if Λ is real valued, any family of optimal pairs (y*, u*) for (Pt,x) whose energy Jt(y*, u*) is equi-boundcd as (t, x) vary in a compact set, has L∞ – equibounded controls. Moreover, if Λ is extended valued, the same conclusion holds under an additional lower semicontinuity assumption on (s, u) ↦ Λ(s, y, u) and requiring a condition on the structure of the effective domain. No convexity, nor local Lipschitzianity is assumed on the variables (y, u). As an application we obtain the local Lipschitz continuity of the value function under slow growth assumptions.
New product development in micro, small, and medium-sized enterprise-based agriculture products: a valuation technology approach
Authors: Dharmawan Budi , Herry Koesoema Elyanto Adwi , Satriani Ratna
Published: November 2022

The innovation from university can assist Micro, Small, and Medium-sized Enterprises (MSMEs) in growing their business. However, because the technology has not been tested, MSMEs are still hesitant to adopt it. As a result, the objective of the research is value the innovation produced by the researcher at university that can add value to MSME products and business development. We employ a technology valuation application as a decision-making tool for valuing and predicting license prices for innovative technology to be commercialized. The use of mangosteen rind powder as a natural preservative on the physicochemical characteristics of coconut sugar had a risk factor of 0.4277, with a technology class of moderate risk, and was located in the technological life cycle's growth area and the product life cycle's diffusion area. The technology license price was IDR 302,042,177 and the diffusion of new technical consumer features was a growing field of innovation. As a result, to attract late adopters, it was necessary to project a positive image of technology beneficial to their health. The study's relevance is based on the patient-oriented technology valuation system, which can anticipate the price of new technology that has the potential to be commercialized.
Competitiveness of Indonesian Rice Prices in The International Market
Authors: Hutapea Ronald T.P. , Prayogo Ramadhan Rizky , Meity Aneke Tulalo , Ngongo Yohanis
Published: November 2022

More than 40 countries produce world rice, only six major exporting countries, namely India, Vietnam, Thailand, Pakistan, Myanmar, and the United States. The availability of rice on the world market annually ranges from 39-42 million tons that 40% of it imported by Asian countries, and China imports 6 million tons per year. Retail rice prices in Japan are USD 5.20/kg, Saudi Arabia USD 2.30/kg, and in Africa around USD 1.0 / kg, higher than Indonesia. The price of medium rice offered in the world market ranges from USD 0.34 - USD 0.4 per kg, while the price of special rice is USD 1,000/ton or more. Indonesia has the opportunity to export Basmati and aromatic rice to Japan and Saudi Arabia, which purchased at high prices. This export opportunities driven by reciprocal bilateral trade. Rice export to African countries needs to be explore under bilateral trade agreements. Indonesia has chance to export rice if it is able to consistently achieve a production surplus of at least 2 million tons per year. At the stage of exports, the role of the government needed in the form of tax breaks, quality assurance certification and subsidies for the rice production process.
The characteristics and potential of the chrysanthemum commodity business and supporting institutions
Authors: Indrasti Rita , Rawung Jefny B. Markus , Tan Siti Sehat
Published: November 2022

The determining factor for the success and sustainability of chrysanthemum agribusiness development is largely determined by the optimal supply chain of the commodity. This study aims to elaborate the strategy for optimizing the supply chain of chrysanthemum agribusiness in Tomohon City, North Sulawesi Province. The research was conducted in September – December 2021, using surveys and FGDs involving farmers and business actors in deliberately selected locations. The data and information collected includes the characteristics and potential of the chrysanthemum commodity business and supporting institutions. In addition to primary data, secondary data from related agencies and results of literature studies were also collected. The collected data were analyzed using supply chain and value chain analysis. The results of the analysis show that the development of agribusiness and supporting institutions in Tomohon has the opportunity to be improved. One of the supply chain optimization strategies can be done with adaptive technology intervention, implementing low-cost strategies, product specifications and quality improvement.
The partial budget analysis of chilli pepper production using netting house IPM technology over the open field
Authors: Sembiring Asma , Koestoni Moekasan Tonny , Prabaningrum Laksminiwati
Published: November 2022

Chili is one of the food-enhanced flavours and eaten by almost a quarter of people daily. One of the factors that influence chili production is pests and diseases infestation. Integrated pest management (IPM) both in the open field and under netting houses could control the chili pests and diseases infestation. The study aims to calculate the economic benefit of chili pepper production using the netting house IPM technology over the open field. The study was conducted from March to December 2021 in Lembang, West Java-Indonesia. Hot beauty chili variety was planted in the open-field and under netting house, each in the size of 1,000m2 by IPM technology. IPM technologies' return was compared to evaluate which IPM technology produces the bigger. Data were analysed using partial budget analysis. The results showed chili production using the technology of IPM netting house generated revenue twofold higher than the IPM open field. It is derived from the saving cost of other expenditures and the additional income. The total profit resulting from IPM netting house production over the open field was 153.5 million (round up). The additional benefit of the IPM under netting house chili pepper production per hectare was 80.9 million IDR.
Cultural Events: Local Sustainable Tourism Development and Entrepreneurship
Authors: Anita Yunikawati Nur , Purboyo Priambodo Magistyo , Sidi Fatimah
Published: November 2022

Cultural events, which are typically owned by a region, are among the world's tourist attractions, including Indonesia. The event's positive impact is the increased number of tourists, which will increase local community business income. However, the negative impact of cultural events can cause environmental damage due to irresponsible visitors. Local community must organize cultural events by encouraging environmental sustainability. The purpose of this study is to examine the factors that influence green entrepreneurial intention, including green entrepreneurial self-efficacy, ecological values, and green entrepreneurial motivation. This study used a quantitative explanatory approach, and the data was processed using PLS-SEM software. Purposive random sampling was used to select 152 participants. The Osing Traditional Tourism Village Indonesia was chosen as the research site.. According to the study, green entrepreneurs' self-efficacy had no direct or indirect effect on green entrepreneur motivation or green entrepreneurial intentions. Ecological value has no direct impact on green core intentions. However, ecological value has no direct impact on green environmental intentions via green entrepreneurial motivation. Motivation for green entrepreneurship influences green entrepreneurship intentions. To summarize, cultural events have a wide-ranging impact on many tourist destinations. The impact of cultural events on destinations is linked to residents' proclivity to conduct business related to cultural events.
Effect of Heating on the Stability of Curcumin on Temulawak Oleoresin Encapsulated in Arrowroot Starch Nanoparticles
Authors: Winarti Christina , Candra Sunarti Titi
Published: November 2022

Storage and heat exposure will cause water absorption and oxidation which lead to degradation and changes in physicochemical properties of the active ingredient and will affect its performance in-vivo. The purpose of the study was to determine the effect of storage and heat treatment on the stability of temulawak-curcumin oleoresin encapsulated with arrowroot starch nanoparticles. The treatments tested included the type of encapsulant which was two kinds of matrixes: two kinds of storing temperature, oven drying, and sunlight exposure. The results showed that the nanoparticle starch matrix had good stability during storage as well as against heat and sun exposure compared to the maltodextrin matrix. The matrix of ethanol precipitation results in better stability during storage than that of butanol precipitation. After storage for 60 days, the reduction of curcumin content was half at room temperature compared to 40C (20 and 40% respectively). Storage at 40C temperature at butanol matrix showed drastic curcumin degradation compared to other matrixes. Meanwhile, the butanol starch matrix showed better protection against curcumin degradation against oven drying heat treatments. Curcumin was too susceptible to sunlight exposure with a level below 10% for both matrixes used.
The effect of aerosol spraying with calcium-containing preparations on basic grape quality indicators of CV. Shokoladniy during long-term storage
Authors: Boyko Vladimir , Levchenko Svetlana , Belash Dmitriy , Romanov Alexander , Cherviak Sofia
Published: November 2022

In this work the effect of post-harvesting aerosol spraying with calcium-containing preparations Master Green Ca (1.75 g/l) and Brentax KCa (2.5 g/l) on changes in the indicators of commercial quality and natural weight loss of grape cv. Shokoladniy in the dynamics of long-term storage was studied. The studies were carried out in 2019-2020. Experimental samples were collected on the 30th and 60th day of storage. It has been established that aerosol spraying contributed to a decrease in the natural loss of bunch weight by 5.7- 6.5%. The amount of total sugars in experimental samples decreased to the 60th day of storage by 15.3% and 10.2% compared to the control. The preparations positively impacted organoleptic indicators during the storage: the tasting assessment of experimental batches of grapes to the end of storage exceeded the control by 6.7-10.3%.
Ecological state of some pasture differences of Haloxylon ammodendron of Karakalpak Ustyurt (Uzbekistan)
Authors: Sharipova Vasila , Rakhimova Tashkhanim , Rakhimova Nodira
Published: November 2022

The article is devoted to the study of the current state of three pasture differences from the Haloxylon pasture type: 1. Haloxylon ammodendron, Caroxylon orientale, Artemisia terrae-albae; 2. Haloxylon ammodendron, Artemisia terrae-albae, Caroxylon orientale with Haloxylon persicum; 3. Haloxylon ammodendron, Artemisia terrae-albae, Anabasis salsa with Haloxylon ammodendron, Kalidium caspicum, Halostachys caspica and Halocnemum strobilaceum are common in the territory of Karakalpak Ustyurt (Uzbekistan). The results of field studies of plant communities with the dominance of Haloxylon ammodendron are presented. The area of the studied pasture differences, the nature of the soil cover, the percentage of projective coverage, landscape plant species, their placement, the yield of feed mass and the recommended seasonality of use are determined. The studied pasture differences are recommended to be used as year-round pastures.
Body percussion and urban rhythms as an interdisciplinary resource
Authors: Romero-Naranjo Francisco Javier , González de Benatuil María Luisamercedes
Published: November 2022

The dual task is an excellent resource for cognitive stimulation, both in healthy people and in people with some cognitive impairment or syndrome, thanks to the latest scientific publications in this field. In this article we propose practical resources linked to the dual motor task with cognitive activities. For this purpose, we implement two known rhythms that help to work on body schema, coordination, dissociation and laterality, among other aspects. The Bapne method is concerned with providing practical resources so that professionals from various fields have the opportunity to use them in their professional circle.
Practice of BAPNE FIT to Improve Cardiorespiratory Fitness
Authors: Romero-Naranjo Francisco Javier , González de Benatuil María Luisamercedes
Published: November 2022

Body percussion in the sciences of physical activity and sport has a specific and exclusive program through the Bapne method in which it unifies motor, rhythmic and cognitive tasks in a parallel way called Bapne FIT. In this article we propose a case study with the aim of studying a subject by means of ergo-spirometry tests performing the exclusive activities of this methodology. For this purpose, respiratory, cardiovascular and metabolic tests will be performed, with the aim of analyzing oxygen consumption and carbon dioxide production in order to obtain data on the muscular metabolic system in relation to Bapne Fit activities.
Palladium-Catalyzed Transfer Hydrogenation and Acetylation of N-Heteroarenes with Sodium Hydride as the Reductant
Authors: Luo Fan , Chen Xiaobei , Hu Ying , Zhang Shilei , Hu Yanwei , Yu Jing , Yin Yuejia , Hu Xiaoxiao , Liu Xuejun , Chen Xiaodong
Published: November 2022

An efficient and convenient palladium-catalyzed reductive system by employing sodium hydride as the hydrogen donor and acetic anhydride as an activator has been developed for transfer hydrogenation and acetylation of a wide range of N-heteroarenes including quinoline, phthalazine, quinoxaline, phenazine, phenanthridine, and indole. Moreover, acridine substrates could be directly reduced without the use of acetic anhydride. This protocol provides a simple method for the preparation of various saturated N-heterocycles.