bluuebunny/crossref_metadata_2025 huggingface dataset:
Representaciones del poder en la Historia troyana polimétrica
Authors: Miguens Agustina
Published: December 2023

La Historia troyana polimétrica (HTP) es una adaptación castellana del Roman de Troie de Benoît de Sainte-Maure, con la particularidad de ser el prosimetrum castellano más antiguo del que se tenga noticia, ya que combina prosa con once composiciones líricas en distintos metros. De autor anónimo y datación controvertida (hacia fines del siglo XIII o mediados del XIV), se conserva en estado fragmentario en los manuscritos facticios 10146 de la BNE (M) y L.jj.16 del Escorial (E), de mediados y finales del XIV, junto con otros textos de temática troyana como la Crónica troyana promovida por Alfonso XI.Este trabajo se propone analizar las representaciones de las figuras de poder más importantes en el relato de la Guerra de Troya en la HTP, para lo cual tomaremos los casos de Agamenón, Héctor y Príamo. Estos héroes clásicos, en consonancia con los procedimientos del roman antique francés, son presentados como caballeros medievales. Consideramos que la adaptación de los relatos de temática troyana puede vincularse con la política caballeresca de Alfonso XI. En el convulsionado escenario del siglo xiv castellano, y como parte de sus propósitos de sometimiento de la nobleza rebelde y fortalecimiento de la Corona, este monarca buscó la renovación de la ideología caballeresca para crear un cuerpo de caballeros leales al rey, con los que pudiera reanudar la “Reconquista”.
Moral values in Ancient Greek Aesthetics
Authors:   Volgograd State Medical University, Tabatadze Georgy S. , Kostenko Olga V. ,   Volgograd State Medical University
Published: December 2023

Abstract. Characterizing the ancient aesthetics, we adhere to the moral approach of the correlation of aesthetic and moral catego-ries, which allows us to reveal the logic of the development of the relationship between aesthetics and morality. In our study, an attempt has been made, in general terms, to consider the development of aesthetics not as the evolution of con-cepts, terms, theories, but as an essential factor in the development of morality, morality, ethics, how the understanding of beauty, beau-ty and harmony in art determined a person's perception of himself and the essence of his actions.
Peningkatan Bantuan Keamanan Amerika Serikat Terhadap Ukraina dalam Konflik Rusia-Ukraina di Era Presiden Joe Biden
Authors: Zahro Lailatul , Albayumi Fuat , Soelistijono Pra Adi
Published: December 2023

Bantuan keamanan yang diberikan Amerika Serikat (AS) terhadap Ukraina mengalami peningkatan sejak terjadinya invasi yang dilakukan oleh Rusia Bantuan untuk Ukraina menjadi bantuan terbesar AS sejak pemerintahan Joe Biden walaupun Ukraina bukan negara anggota sekutu AS di kawasan Atlantik Utara (NATO) maupun tetangga dekat. Tulisan ini bertujuan untuk mengetahui motif peningkatan bantuan keamanan AS terhadap Ukraina dalam konflik Rusia-Ukraina di era Presiden Joe Biden. Artikel ini menggunakan metode kualitatif dengan pengumpulan data menggunakan studi pustaka, dan analisis data deskriptif-kualitatif. Hasil penelitian menunjukkan bahwa Amerika Serikat menggunakan bantuan keamanan kepada Ukraina untuk membendung pengaruh Rusia, memperluas pengaruh sekaligus menyebarkan demokrasi di Ukraina, maupun kawasan Eropa Timur. Ini merupakan bukti bahwa asumsi neorealisme yang menyatakan bahwa negara superpower merupakan aktor utama hubungan internasional terkonfirmasi benar dalam konflik Rusia-Ukraina, terbukti dari bantuan AS kepada Ukraina dalam konflik tersebut.
Adatok Csepel molylepkefaunájának ismeretéhez (Lepidoptera)
Authors: Tóth Balázs
Published: December 2023

Csepel lepkefaunájáról még nem látott napvilágot összefoglaló mű annak ellenére, hogy több, faunisztikai és természetvédelmi szempontból igen értékes lepkefajnak ismert innen történeti adata. Gyűjtéseimet Királyerdőn, a Hollandi út és a Ráckevei (Soroksári)-Duna által határolt terület beépítetlen részén, valamint a Hollandi út és a Matróz utca sarkán álló telek kertjében végzem 1999 óta, kisebb-nagyobb megszakításokkal. A vizsgált területről idáig 109 molylepkefajt mutattam ki, melyek a következő családok között oszlanak meg (zárójelben az odatartozó fajok száma): Heliozelidae (2), Adelidae (4), Tineidae (5), Plutellidae (1), Gracillariidae (8), Pterophoridae (1), Tortricidae (8), Autostichidae (1), Oecophoridae (4), Depressariidae (2), Cosmopterigidae (2), Gelechiidae (3), Batrachedridae (1), Scythrididae (1), Zygaenidae (2), Cossidae (3), Sesiidae (6), Pyralidae (12), Crambidae (43). A fajok adatait ebben a munkában sorolom fel. Faunisztikai érdekességet jelent a Phyllocnistis valentinensis Hering, 1936, a Phyllocnistis vitegenella Clemens, 1859, az Epicallima bruandella (Ragonot, 1889), a Batrachedra enormis Meyrick, 1928, a Zygaena punctum Ochsen­heimer, 1808, az Aglossa caprealis (Hübner, 1809), az Antigastra catalaunalis (Duponchel, 1833) és a Duponchelia fovealis Zeller, 1847 fajok előkerülése.
Vivendo das ruas
Authors: Freiesleben Mariane , Pizzio Alex
Published: December 2023

Este artigo explora a expansão do trabalho de rua e da informalidade nas cidades do norte do Brasil, particularmente em Palmas, Tocantins. Analisa os fatores estruturais que sustentam essa forma de trabalho e destaca a importância do trabalho de rua na construção da identidade social dos trabalhadores. O estudo é baseado em 50 entrevistas realizadas ao longo de 24 meses e revela que a informalidade em Palmas é estrutural e que a confiança desempenha um papel central nas relações sociais e econômicas dos trabalhadores de rua.
PALEOCARPOLOGICAL COMPLEXES OF DEPOSITS OF THE SECOND HALF OF THE LATE PLEISTOCENE IN THE KYSYL-SYR TUKULAN REGION AND ITS ENVIRONS (CENTRAL YAKUTIA)
Authors:   Siberian Research Institute of Geology, Geophysics and Mineral Resources, Novosibirsk, Russia, Mikharevich M. V. ,   P.I.Melnikov Permafrost Institute SB RAS, Yakutsk, Russia, Galanin A. A. ,   P.I.Melnikov Permafrost Institute SB RAS, Yakutsk, Russia, Kuzmina S. A. ,   Paleontological Institute RAS, Moscow, Russia, Vasilyeva A. N. ,   P.I.Melnikov Permafrost Institute SB RAS, Yakutsk, Russia, Lytkin V. M. ,   P.I.Melnikov Permafrost Institute SB RAS, Yakutsk, Russia, Balisyan A. E. ,   Geological Institute RAS, Moscow, Russia
Published: December 2023

Paleocarpological complexes from sections of Central Yakutia including from the aeolian Dyolkuma Formation were established for the first time. The original method of sampling from deposits of deflation lakes is given. The complexes of the Dyolkuma Formation generated in the last thermochron and cryochron of the Late Pleistocene were compared with each other, as well as with complexes of alluvial formations (MIS-3) and the Yedoma Formation (MIS-2) synchronous with them. Southern thermophilic aliens were found in samples from sediments compared with MIS-3. The data obtained made it possible to significantly supplementand define the previously performed paleogeographic reconstructions. Thermoarid steppe formation was determined against the background of the development of forest communities in the last Neo-Pleistocene thermochron in the conditions of intrazonal landscapes,within which the thermal erosion of permafrost was manifested; and the existence of woody vegetation areals in the subsequent cryochron was also noted. The research results can serve as a basis for stratifying similar deposits and performing correlations with other sections of the area.
COST ESTIMATE AS A TOOL FOR MANAGING FRESH GROUNDWATER RESOURCES IN THE RUSSIAN FEDERATION
Authors:   Saint Petersburg Mining University, Saint Petersburg, Russia, Golovina E. I. , Tselmeg Bayarkhuu ,   Saint Petersburg Mining University, Saint Petersburg, Russia
Published: December 2023

Groundwater, being an unconditional economic resource, as a mineral, has a number of features that affect various areas of national economy. In addition to the function of providing raw materials for the social sphere, groundwater indirectly creates the basis for economic activity in almost all areas of industry and agriculture. The resource potential of this most important mineral, especially freshwater is located very unevenly across the planet regions, while the demand for it is constantly growing, which is, among other things, a prerequisite for the emergence of international conflicts. The high costs of transportation, storage and extraction of groundwater resources make us talk about the complex economic aspects of this segment in the economy of many states. At the same time, countries and regions with excessive groundwater reserves do not always perceive them as an economically significant resource, as a result of which public administration issues in this area do not have systematic long-term planning. Currently, there is no methodology for determining the valuation of an underground water resource on the territory of the Russian Federation. The market mechanism is applicable only to certain types of mineral therapeutic and industrial groundwater that are commercial products, including MET. The comparative characteristics of surface and groundwater are carried out from the point of view of marketable products, the features of the tariff policy formation are considered as a realization element of the resource water potential.
IRON-ORE BASIN OF THE KURSK MAGNETIC ANOMALY. THE HISTORY OF THE GREATEST DISCOVERY OF THE FIRST HALF OF THE XX CENTURY IN RUSSIA. PART I. NATURAL PHENOMENON OF KURSK PROVINCE
Authors:   State Geological Survey of the Ministry of Natural Resources by Kursk oblast, Kursk, Russia, Emelyanov A. I.
Published: December 2023

In April 2023, exactly 100 years have passed since the iron-ore core was taken from a well drilled in the Shchigry area of Kursk province, thereby the secret of the Kursk magnetic anomaly nature was revealed and the beginning of the world’s largest iron-ore deposits development was marked. This article is devoted to the history of one of the greatest discoveries of geologists of the first half of the 20th century, full of action-packed and dramatic events.
A ÁRVORE DO CONHECIMENTO: DEMOCRATIZANDO O ACESSO ÀS TECNOLOGIAS DIGITAIS
Authors: Coelho George leonardo seabra coelho , Siqueira de Melo Andréa , Ribeiro da Silva Santos Anny Karoline , Rodrigues dos Santos Geovanna , Nogueira Cancian Lucas , Porto Sousa Marcella , Ribeiro Souza Mikaelly Ester , Giuvannucci Rosa Nilsion
Published: December 2023

Com base nos debates sobre os usos das tecnologias e mídias digitais, assim como suas relações com processos educativos, em especial, no contexto de isolamento social provocado pela pandemia da Covid-19, esse Projeto de Inovação Pedagógica ampliará o debate e a aplicação das TDIC ao longo do ano de 2021. Sendo assim, propomos desenvolver diversas atividades e ações que possam contribuir de forma significativa na minoração dos prejuízos formativos provocados pelo distanciamento social e, consecutivamente, na adoção de modalidades assíncronas e síncronas nos Cursos de Graduação e Pós-graduação. Nosso objetivo foi o desenvolvimento de suportes tecnológicos digitais para contribuir no processo ensino-aprendizagem da comunidade acadêmica do Curso de História de Porto Nacional.
Application of Problem-based Learning Assisted by Decision Maker Application on Computational Thinking Materials to Improve Student Learning Outcomes at SMP Negeri 2 Gemolong Sragen Regency
Authors: Tri Wardoyo Indriyanto , Basori Basori , Wulansari Astika
Published: December 2023

This research is a classroom action research, which aims to improve student learning outcomes in the informatics subject matter of computational thinking. This study applies Problem-based learning assisted by decision-makers on smartphones. Students are directed to download and install the decision-maker application on their smartphones. Then students use the information in the application as a reference for information as material for discussion with their respective groups. From the results of the summative assessment, the data showed an increase in the average value of learning outcomes in each cycle.
Compost of peanuts residue and rice straw compost on soil Nitrogen forms and upland rice yield
Authors: Sholihah Anis , Sugianto Agus , Lestari Mahayu Woro
Published: December 2023

This study provides an innovation in making compost from rice straw (low quality) mixed with peanut residue (high quality) to improve the quality of rice straw compost. The purpose of this research was to discover the optimum composition of a mixture of peanut residue and straw for mineralization, absorption, and Nitrogen Use Efficiency (NUE) and its effect on upland rice plants. The study was conducted in three stages. The first stage determined the quality of five compost mixtures: C1, C2, C3, C4, and C5. The second phase of testing for cumulative N minerals was performed after 1, 2, 4, and 8 weeks of incubation. The third stage examined the impact of the compost mixture on the growth and yield of upland rice in comparison with two treatments, namely the control and NPK fertilizer. The results showed a similarity in the forms of mineralization, where the cumulative N mineral increased with the addition of peanut residue to the compost mixture. The use of a mixture of peanut residue and rice straw compost increased net mineralization by 37.27% (C5) to 59.48% (C1), N uptake by 49.19% (C5) to 62.95% (C3), and NUE by 15.04% (C4) to 51.48% (C3). A strong relationship was detected between the quality of the compost and the forms of N in the soil, particularly the nitrate content, total N minerals, and N microbial biomass, with correlation coefficients of 0.92, 0.88, and 0.94, respectively. A strong to very strong relationship was detected between N form and N uptake (r = 0.84), plant height (r = 0.79), number of tillers (r = 0.78), yield of rice plants (r = 0.93 (plant total dry weight), and r = 0.76 (grain weight). The optimum N uptake, NUE, and yield of upland rice were shown by C3 treatment of 405.28 mg pot-1, 42.21%, and 6.19 tons ha-1, respectively.
Stress concentration reduction in an axially loaded rectangular bar with an elliptical hole
Authors: Ramírez Monares José Alfredo , Gamboa Soto Leonel
Published: December 2023

Two-dimensional finite element analysis was used for stress concentration factors estimation in a wide range of bar-ellipse height and height-width elliptical hole ratios in a tensile bar. Least squares polynomial equations were fit to the design points. These equations agreed and tension stress concentration factor for elliptical holes was described. Such equation reproduces the curves and through its derivative the optimal values that minimize the concentration factor are estimated. The path of the minimal concentration factor was illustrated in a contour plot.
Analytical review of court decisions on claims of patients to medical organizations
Authors: Bezugly T. A. , Tyukov Y. A. , Mochalov Y. A. , Kondakova V. D.
Published: December 2023

Introduction. The professional activity of medical workers is regulated by legislation aimed at reducing risks for patients. In recent years, the number of patient lawsuits against medical institutions has increased significantly. The main reasons for dissatisfaction with the quality of medical care are errors in medical documentation, medical errors and non-compliance with the principles of medical ethics. The analysis of judicial practice is important for optimizing court costs and resolving conflicts in a pre-trial manner.

The purpose of the study is to analyze the court decisions made on the claims of citizens to a medical organization on the quality and result of medical care.

Methods. The study analyzed 56 decisions of the courts of general instance issued over five years – from 2018 to 2022, in court proceedings in which clinical hospitals appeared as a defendant.

The main conclusions that can be distinguished from the analysis are that most cases involving compensation for moral damage from medical institutions are based on incorrect treatment, incorrect diagnosis or violation of the right to preferential medical services. In some cases, the courts take the side of the defendant, reject the claim or conclude a settlement agreement. In cases of defeat in court, hospitals pay moral compensation to plaintiffs in various amounts, from 2 thousand to 1.3 million rubles.
Re-visiting the Nexus Between Energy Consumption, Environmental Quality and Health Expenditure in Gulf and North American Regions
Authors: Zeeshan Muhammad , Rehman Alam , Ullah Irfan
Published: December 2023

The dynamic relationship between energy consumption, environmental quality and health expenditures have been explored at country as well as regional level, but research on the comparison of regions in the paradox of these variables of interest is rare in the body of knowledge. Therefore, this paper attempts to investigate the relationship between energy consumption, environmental quality and health expenditure as the relationship of these variables in the context of GULF and North American regions is center of attention in the research community due to their emerging landscape. We use the data of seven GULF countries and the same number of countries from North American regions using Penal-ARDL and PMG-ARDL for the period 1990 to 2019. Our results demonstrate that energy consumption increases CO2 emission in GULF as well as North American region, but the effect of energy consumption on the health expenditure in GULF region is statistically insignificant which may be due to protective initiatives in GULF region. Whilst, CO2 emissions is contributing to more health expenditures in both regions, indicating that more CO2 emissions threatening the health quality in both regions. Our results are very pivotal to the policy makers in these regions for their strategic landscape to make frameworks that could be effective to obtain health quality and environmental milestones.
An exploration of how online media portrays asthma and its treatment in New Zealand
Authors: Chan Amy , Scahill Shane , Zhu James , Qin Ziyi , Lin Christina , Hameedi Saliha , Pinnock Hilary , Aspden Trudi
Published: December 2023

Introduction Asthma is one of the most common long-term conditions worldwide. Mass media can influence public perceptions of asthma and its treatment, yet there is limited literature on how online media portrays asthma and asthma treatment. The aim of this study is to explore the portrayal of asthma and inhaled treatments in online mass media in New Zealand.Methods Documents available between 2014 and 2019 were retrieved from national patient support organisations and online news outlets. Documents were screened for inhaler images and mentions of two or more keywords relating to asthma. Asthma medication manufacturers were contacted to access direct-to-consumer advertisements. A coding instrument was developed to quantitatively analyse the retrieved documents.Results In total 124 documents were retrieved and analysed; 59 from patient support organisations and 65 from online news websites. No online direct-to-consumer advertisements were retrieved. Using inhalers was the most frequently cited asthma management strategy (84%, 84/100). Metered dose inhalers were the most common inhaler device (78%, 175/225) portrayed or mentioned and blue was the most common colour (48%, 109/225). Under half (45%) of metered dose inhalers were shown with a spacer. Online press items contained more emotive themes such as challenge, fear, and stigma content than resources from patient support organisations.Conclusion Blue-coloured metered dose inhalers, traditionally associated with relievers, were the most commonly depicted devices in New Zealand online mass media. Most online news articles used emotive language when discussing asthma and asthma treatments, while patient support organisations used more objective language. How media influences public perceptions of asthma and its treatment needs to be considered by health promoters.
Leveraging Feature Fusion Ensemble of VGG16 and ResNet-50 for Automated Potato Leaf Abnormality Detection in Precision Agriculture
Authors: Trivedi Amit , Mahajan Tripti , Maheshwari Tanmay , Mehta Rajesh , Tiwari Shailendra
Published: December 2023

In the era of advancement in technology and modern agriculture, early disease detection of potato leaves will improve crop yield. Various researchers have focused on disease due to different types of microbial infection in potato leaves using computer vision and machine learning approaches. In this paper, a data science approach for multiclass classification of potato normal and abnormal leaves due to fungal infection like early blight and late blight is performed using the ensembling of deep learning (DL) CNN models. Firstly, the performance of classification on potato disease is verified separately on VGG16 and ResNet−50 CNN models after pre-processing of the leaf dataset. The pre-processing includes noise removal and normalization. Further improvement in classification accuracy is achieved by the ensembling of VGG16 and ResNet−50 CNN models. The ensembling of CNN models is performed on the feature level by fusing features extracted using VGG16 and ResNet−50. From the experimental results, performed on publicly available datasets consisting of 2152 number of normal and abnormal images it is observed that the average classification accuracy of 98.22%, 96.16% and 95.68% is achieved using the proposed ensemble, VGG16 and ResNet−50 models respectively. The efficacy of the proposed approach (ensemble technique at feature level fusion) is verified in comparison with recently reported DL model-based approaches.
Enhancing global food security through the introduction of Maximum Sustainable Yield targets in fisheries
Authors: Elleby Christian , Dominguez Ignacio , Costello Christopher , Best Barbara , Lirette Paul , Hoff Ayoe , Nielsen Max , Nielsen Rasmus
Published: December 2023

Calories and protein from aquatic sources play a crucial role in ensuring global food and nutrition security. Additionally, fishing serves as a vital source of income in developing countries. Nevertheless, overfishing has resulted in fish stocks, falling below their most productive (maximum sustainable yield - MSY) levels and, if current trends persist, the consequences could be severe. To address these concerns, we examine the potential effects of implementing a global MSY management target on catches and the agri-food markets over time. Our results indicate that sustainable management of overfished stocks would lead to lower catches in the short-medium term (~10 years) and vice versa in the longer term. The long-term sustainable increase in total catches (~16 Mt), would alleviate the need for a significant expansion in aquaculture production and reduce the demand for alternative protein resources, such as meat. Moreover, the resulting lower food prices could enhance global food security.
Synchronously generating ultrashort pulses of electromagnetic radiation and electron beam for ultrahigh spatio-temporal resolution characterization
Authors: Deng Shao-Zhi , Shen Yan , Xu Ningsheng , Cao Zhaolong , Song Zheyu , Han Dong , Xie Songyang , Xing Yang , Chen Huanjun
Published: December 2023

Ultrashort pulsed electron beam with high brightness and low energy spread enables ultrahigh resolution of spatio-temporal characterization of materials and devices. So far, this is done using ultrashort electron pulse as probe and ultrashort laser pulse as pump. Adding powerful analytical capability with multimode-excitation is urged to meet rapidly rising need. We envision that it will provide plentiful new insides if characterizations are carried out with excitation simultaneously using ultrashort electron pulses and ultrashort electromagnetic wave pulses. In particular, for brain science and Internet of Things (IoT), electromagnetic wave is an unavoidable existing factor, such as in brain neuroscience and brain computer interface. Here, it is revealed that an ultrashort pulsed electron beam itself radiates electromagnetic waves. We demonstrate that both ultrashort pulsed electron beam and GHz’s electromagnetic waves may be synchronously generated by a photo-excited electron emission using picosecond laser of a few milli watts and 80 MHz. We also establish a systematic study for obtaining crucial characteristics of the pulsed electron beam, including energy spread as low as 0.97 eV, current density over 0.9 A·cm− 2, spot diameter < 145 µm, divergence < 14.22°, high reduced brightness up to 8.81×109 A·m− 2·sr− 1·V− 1. The synchronous electromagnetic wave pulses carry high frequencies of 2.3, 5.7, and 9.2 GHz, with peak power density over 90 mW·cm− 2 at pulsed charge below 0.7 pC. The results satisfy ultrahigh spatio-temporal resolution characterization of multimode-excitation, and provide a pioneering direction that previously impossible, to reveal new insides of materials and devices concerned with brain science and IoT.
Induction therapy with oral tacrolimus provides long-term benefit in thiopurine-naïve refractory ulcerative colitis patients despite low serum albumin levels
Authors: Igawa Shoko , Inokuchi Toshihiro , Hiraoka Sakiko , Toyosawa Junki , Aoyama Yuki , Yamasaki Yasushi , Kinugasa Hideaki , Takahara Masahiro , Okada Hiroyuki , Otsuka Motoyuki
Published: December 2023

Oral tacrolimus is an effective treatment for refractory ulcerative colitis (UC). However, tacrolimus is underutilized because of the difficulties in transitioning to subsequent maintenance therapy and concerns about adverse events. We evaluated the clinical outcomes, adverse events, and accumulated medication costs in consecutive 72 UC patients treated with tacrolimus. Fifty-five (76%) patients with pancolitis and 43 (60%) patients with acute severe disease were entered. Fifty-four (75%) achieved clinical remission 8 weeks after starting tacrolimus. At the last visit, 62 (86%) patients had colectomy-free remission and 55 (76%) patients had corticosteroid-free remission. Eighteen (25%) patients maintained remission without additional treatment after tacrolimus discontinuation. Patients with continuous remission had significantly a lower history of thiopurine use and lower serum albumin levels at the induction of tacrolimus than patients with failure to induce or maintain remission. No severe adverse events due to tacrolimus treatment were observed. The accumulated medication costs over 3 years in patients with continuous remission after the start of tacrolimus were lower than those in patients with induction and maintenance of infliximab (p < 0.001). Tacrolimus could have an irreplaceable role in the era of biologic therapies, especially for refractory UC patients with thiopurine-naïve and low serum albumin levels.
Geospatial Analysis of Soil Resistivity and Hydro-Parameters for Groundwater Assessment
Authors: Javed Umar , Kumar Pradeep , Hussain Sajjad , Nawaz Taufiq , Fahad Shah , Ashraf Shahbaz , Ali Karamat
Published: December 2023

Groundwater is a precious resource for irrigating the crops in developing countries. This research was governed in Faisalabad District of Pakistan to assess the groundwater strata using GIS cum geoelectric resistivity method approach. The IX1D computer model was used to obtain true soil layers’ resistivities and thicknesses for each VES point based on apparent resistivity data collected by Resistivity meter using Schlumberger electrode array setting. Geo-hydraulic parameters (hydraulic conductivity, transmissivity, and porosity) were also calculated based on modeling results (soil layers resistivities and thicknesses). Interpolation (inverse distance weighted) method in ArcGIS Pro was used for mapping the soil aquifer layers resistivities/thicknesses and geo-hydraulic parameters. Transmissivity, Porosity, and hydraulic conductivity values ranged from 365.46 to 1888.503 m2/day, 31.84 to 39.72% and 4.05 to 15.27 m/day for all surveys respectively. Based on these results, aquifer layers with thicknesses 30 to 103.5 m, were distinguished as comprised of saline to low marginal quality (fine sand and clay formation), marginal to fresh quality (fine sand and gravel formation) and fresh quality groundwater (coarse sand and gravel formation).
Essential newborn care practices at health facilities and homes in Ethiopia: A cross-sectional study
Authors: Guadu Tadesse , Alemu Kassahun , Schellenberg Joanna , Berhanu Della , Lemma Seblewengel , Defar Atkure , Getachew Theodros , Taye Girum , Shiferaw Solomon , Abdissa Zewditu , Tariku Amare , Zelalem Meseret , Persson Lars Åke
Published: December 2023

Background
WHO recommends a set of essential newborn care practices that every newborn baby needs for health and survival regardless of birthplace. Previous Ethiopian studies of these actions had long recall periods, and most considered either facility or home deliveries. We aimed to assess selected practices, i.e., thermal care, cord care, initiation of breastfeeding, and first six-weeks immunizations among neonates born at health facilities and homes in Ethiopia.
Methods
We used data from the Performance Monitoring for Action Ethiopia 2019–2021 survey and analyzed 2,493 live births who completed interviews at six weeks postpartum in five regions, namely Tigray, Afar, Amhara, Oromia, Southern Nations, Nationalities and Peoples regions, and Addis Ababa. Practices were assessed using an interviewer-administered questionnaire. Essential newborn care indicators were analyzed among neonates born at health facilities and homes and expressed as proportions with a 95% confidence interval. Clustering was accounted for in all analyses.
Results
Practices were assessed among 1543 (62%) facility-delivered and 950 (38%) home-delivered neonates. Some of the appropriate actions had higher coverage among facility-delivered vs. home-delivered neonates: skin-to-skin care 76% vs. 8%, immediate drying and wrapping with a cloth 80% vs. 79%, delayed bathing until 24 hours after birth 72% vs. 39%, appropriate instrument to cut the cord 100% vs. 94%, use of new or boiled instrument 90% vs. 79%, nothing or chlorhexidine applied on cord 89% vs. 64%, first-hour initiation of breastfeeding 69% vs. 62%, and BCG and first polio immunization within the first six weeks after birth 54% vs. 19%. Thermal care, cord care and provision of vaccines at birth were relatively better in Addis Ababa, while first-hour breastfeeding initiation was higher in Oromia region.
Conclusion
Neonates born at health facilities had higher, although not optimal, coverage of thermal care, cord care, early initiation of breastfeeding, and the first immunizations. Strengthening the health extension program to promote facility delivery, further enhancing the coverage and quality of essential newborn care at health facilities, and increasing the coverage of first vaccinations and other essential services after birth is crucial for improving neonatal health and survival in Ethiopia.
The hallmark of the NhaA structural fold-crossing of two transmembranes- is critical for antiporter activity
Authors: Rimon Abraham , Amartely Hadar , Padan Etana
Published: December 2023

Cell pH and Na+ homeostasis requires Na+/H+ antiporters. The crystal structure of NhaA, the main Escherichia coli Na+/H+ antiporter, revealed a unique NhaA structural fold shared by prokaryotic and eukaryotic membrane proteins. Out of the 12 NhaA transmembrane segments (TMs), TMs III–V and X–XII are topologically inverted repeats with unwound TMs IV and XI forming the X shape characterizing the NhaA fold. We show that intramolecular cross-linking under oxidizing conditions of a NhaA mutant with two Cys replacements across the crossing (D133C-T340C) inhibits antiporter activity and impairs NhaA-dependent cell growth in high-salts. The affinity purified D133C-T340C protein binds Li+ (the Na+ surrogate substrate of NhaA) under reducing conditions. The cross-linking traps the antiporter in an outward-facing conformation, blocking the antiport cycle. As many secondary transporters are found to share the NhaA fold, including some involved in human diseases, our data have importance for both basic and clinical research.
Thai Grammatical Error Correction for Deaf Students
Authors: Traitruengsakul Supachan , Chuangsuwanich Ekapol
Published: December 2023

Deaf students encounter challenges in written communication due to errors such as insertion, deletion, disorder, misusage, and misspellings. Grammatical error correction (GEC) technology can help mitigate these issues. However, existing GEC models are primarily trained on online resources from second-language hearing learners. In contrast, sentences written by deaf students suffer from a variety of errors not typically found elsewhere.To address this issue, we create the Thai Deaf Corpus (TDC), focusing on identifying and analyzing errors among deaf students in grades 7-12 across four deaf schools. Additionally, we introduce a two-stage system for the Thai-GEC model, automatically detecting and correcting incorrect words in ungrammatical sentences written by deaf students.In our experiment, we compare the performance of the recurrent neural networks (RNN) detection model with and without feature embeddings from different sources—TDC and News corpus; moreover, we compare three correction models: WangchanBERTa and Seq2Seq models with and without pretraining. Our analysis of the TDC shows that deaf students use simpler words and shorter sentences compared to hearing peers, who often use complex vocabulary and lengthy sentences. The RNN detection model with feature embeddings learned from only TDC can outperform the others. The Seq2Seq correction model with pretraining outperforms others as it learns from formal and grammatical sentences in the News corpus. The dataset is made available at https://github.com/Supachan/ThaiDeafCorpus.git
First records of Secretargas transgariepinus (Argasidae) in Libya and Jordan: corrections of collection records and detection of microorganisms
Authors: Ševčík Martin , Špitalská Eva , Maliterná Michaela , Kabát Peter , Benda Petr
Published: December 2023

The primarily bat-associated argasid, Secretargas transgariepinus (White, 1846), is a member of the Afrotropical and southern Palaearctic fauna. Probably because of its secretive life style, little is known about this species and records of its collection are scant. Based on morphological revisions of the available specimens, we report new Middle Eastern records for this tick species, that had been misidentified as other bat-associated argasid taxa. These specimens are larvae from three localities, and represent the first records of S. transgariepinus from two countries: one larva from Sabratha (Libya) was collected from an unidentified bat (possibly Eptesicus isabellinus), seven larvae from Azraq-Shishan (Jordan), and 78 larvae from Shamwari (Jordan) were all collected from Otonycteris hemprichii. Twenty larvae from Shamwari were also tested for the presence of both, viral or bacterial microorganisms by PCR. Three ticks were found to be infected with the Murine gammaherpesvirus 68, one with Borrelia burgdorferi sensu lato, and four with a Rickettsia sp. closely related to Rickettsia slovaca. The findings represent a first evidence for the occurrence of these possible pathogens in S. transgariepinus.
Transient Heat Flux Assessment Using a Platinum Thin Film Sensor for Short-Duration Applications
Authors: Dongare Sumedh , Peetala Ravi K. , Gohil Trushar B. , Agrawal Nidhish , Jadhav Akash
Published: December 2023

The rapid fluctuations in heat transfer rates make it challenging to determine the surface temperature history and the estimation of accurate heat generation in research applications such as IC engines, gas turbines, and high-speed space vehicles. Therefore, thin-film gauges (TFGs) are generally used to measure the heat flux in such applications due to their high sensitivity and quick response time. The present study demonstrates that increasing the annealing heat treatment temperature, will enhance the adhesion of the thin film and the capabilities of these handmade thin-film gauges for transient measurements at low temperatures and for short periods. In the present work, TFG is fabricated in-house using platinum as a sensing element and Macor as an insulating substrate. The sensitivity (S) and temperature coefficient of resistance (TCR) are estimated using an oil batch calibration technique. At the same time, the performance of TFG is tested in a dynamic convective environment. The TFG is exposed to the convective environment using a designed calibration setup , and their transient heat fluxes are computed by conducting several trials. Additionally, the numerical solution has been accomplished using various experimental parameters. In comparison to the outcomes of the experimental method, it is observed that the average fluctuating temperature and mean surface heat flux have an inaccuracy of 0.33% and 4.17% respectively.
The Effect of Family-Oriented Organized Motivational Program on Working Memory in the Children with Autism Spectrum Disorder
Authors: Afshari Javad , Afshari Nahideh
Published: December 2023

Working memory plays an important role in learning. In this study, we are looking for motivational ways to stimulate memory. The participants (8 girls and 10 boys) were divided into experimental and control groups. They are selected from among 28 subjects after primary tests to be matched. The design of the study is semi-experimental including an independent variable, a pretest and a posttest. After considering the research hypotheses, using descriptive statistics and one-way Analysis of Covariance (ANCOVA), the results suggested a significant difference in posttest scores of experimental and control groups after independent variable being applied. The results show that a motivational program including math assignments and naming shapes assignments that it has coincided with children's motivations can has a positive effect on working memory in children with autism spectrum disorders. Due to increase in brain cognitive functions which control motivation and memory, memory experienced a high level of performance which can lead to more learning.
Time-variation study and OSMAC approach on fumonisin B1 and other mycotoxin production by Fusarium verticillioides.
Authors: Groppi Emie , Gadea Alice , Cristofoli Valérie , Vansteelandt Marieke , Haddad Mohamed
Published: December 2023

Fusarium verticillioides is a plant pathogenic fungus that can cause disease in a variety of crops, including corn, sorghum, and cotton. It is commonly found in soil, but can also be found in infected seeds and plant debris. This fungus produces several mycotoxins, including fumonisins, which can be harmful to both humans and animals if ingested in high concentrations. It can also produce other toxins such as "emerging" mycotoxins like beauvericin, fusaproliferin and others. In this study, we aimed to expand our understanding of mycotoxin production by F. verticillioides according to the substrate. To do so, we investigated the ecophysiology of F. verticillioides under different culture conditions (media, humidity, temperature) over time through UHPLC-HRMS/MS analysis and a dereplicative approach. Our results showed a modification of the fungal growth but also a variation of the nature and the relative concentrations of the mycotoxins produced along the time according to the modifications of culture conditions. This experiment showed that corn meal agar (CMA) medium (MEA) was favorable for fumonisin A1 (FA1), fumonisin B1 (FB1) and fumonisin B2 (FB2) production while malt extract agar medium was favorable for fumonisin A2 (FA2) production. This study allowed us to understand the development conditions of this fungus and the occurrence of its mycotoxins depending on its substrate.
Single-cell sequencing reveals transcriptional dynamics regulated by ERα in mouse ovaries
Authors: Hu Qicai , Gui Yiqian , Cao Congcong , Xie Jun , Tang Huiru
Published: December 2023

Estrogen receptor α (ERα) is a crucial regulator of reproductive function, mediating the diverse effects of estrogen on the development and function of the ovary. However, the molecular mechanisms underlying ERα-regulated transcriptional dynamics in ovarian cells remain poorly understood. In the present study, we generated ERα knockout (αERKO) mice through CRISPR/Cas9 strategy. Then we employed single-cell RNA sequencing technology (scRNA-seq) to profile the transcriptomes of individual cells in wild type (WT) and αERKO mouse ovaries to uncover novel insights into ERα-regulated transcriptional change and ovarian cellular heterogeneity. Using several bioinformatics analyses, our study identified distinct cell populations within the ovarian tissue, including 5 distinct cell clusters associated with oocytes and 7 with granulosa cells. We further conducted differential gene expression analysis to explore the transcriptional profiles of these cell populations in response to ERα deletion. Our findings revealed that ERα deletion led to the dysregulation of genes involved in ovarian infertility, ovulation cycle, and steroidogenesis in oocytes and granulosa cells, indicating that ERα plays a central role in modulating the transcriptional landscape of ovarian cells. Consequently, we confirmed that Greb1, a prototypical ERα target gene, was induced by ERα binding to ERE upstream of the Greb1 promoter in granulosa cells. Additionally, we uncovered a complex network of signaling pathways that were significantly modulated by ERα, implicating their involvement in the regulation of ovarian function and ovulation process. In conclusion, our study offers an in-depth, single-cell resolution of ERα-regulated transcriptional dynamics in mouse ovaries, enhancing our understanding of ERα's role in female reproductive biology and providing potential targets for novel therapeutic interventions for ovarian disorders.
A first alert of Biomphalaria pfeifferi in the Lower Shire, Southern Malawi, a keystone intermediate snail host for intestinal schistosomiasis
Authors: Nkolokosa Clinton , Mbewe Rex , Chirombo James , Stanton Michelle C. , Jones Christopher M. , Makaula Peter , Namacha Gladys , Chiepa Blessings , Kalonde Patrick Ken , Baluwa Chifuniro , Zembere Kennedy , Kambewa Aisha , Kaonga Chikumbusko Chiziwa , Archer John , Juhász Alexandra , Cunningham Lucas J. , Tangena Julie-Anne Akiko , Stothard J. Russell
Published: December 2023

Repeated malacological surveys were conducted in Chikwawa and Nsanje Districts in the Lower Shire River, Southern Region of Malawi to alert to and to characterize populations of Biomphalaria pfeifferi. Sampling took place across a total of 45 sites, noting water conductivity, pH, temperature, total dissolved salts (TDS) and geographical elevation. Subsequently, the presence or absence of snails was predicted upon physiochemical and environmental conditions in Random Forest modelling. A concurrent molecular phylogenetic analysis of snails was conducted alongside molecular xenomonitoring for the presence of pre-patent infection with Schistosoma mansoni. Water conductivity, TDS and geographical elevation were most important in predicting abundance of snails with water temperature and pH of slightly less important roles. Our first alert with geographical modelling of populations of B. pfeifferi in the Lower Shire River is a critical step towards improving understanding of the transmission of intestinal schistosomiasis and a more solid foundation towards developing complementary strategies to mitigate it.
Exploring Gene Expression Dynamics for Sustainable Yield Enhancement in Chickpea
Authors: Mahto Rohit Kumar , B.S. Chandana , Singh Rajesh Kumar , Kumar Arun , Kumar Sudhir , Yadav Renu , Dey Debashish , Kumar Rajendra
Published: December 2023

Background
Chickpea, scientifically known as Cicer arietinum, is considered one of the essential crops due to its significant agricultural and economic importance. These leguminous plants are relatively large in genome size with 738 megabases. Chickpea roots play a crucial role in symbiotic relationships by forming nodules.
Results
20 genotypes were selected from an association panel meant for genome wide association studies on number of nodules and other nodulation traits. Before planting the seeds, the soil was prepared by mixing fertilizers and the specific microorganisms as biofertilizers viz; VAM and Rhizobium. The biofertilizers namely VAM, NPK, Rhizobium, and their 8 combinations in randomized block design with 3 replications were used as growing medium. The treatment mixture of NPK and Rhizobium showed significant performance in all the 20 genotypes by recognizing a genotype as the best one for the trait number of nodules. The morphological and molecular data observed on the subset comprising of 20 genotypes was subjected to descriptive statistics, correlation, path analysis, agglomerative hierarchical clustering, principal component analysis, gene expression analysis and identified the combination of Rhizobiumand VAM the best treatment along with novel donor as ICC- 9085 for the trait number of nodules and to achieve chickpea sustainable productivity.
Conclusions
The study shows the significant positive effects of VAM, NPK, Rhizobium, and their combinations playing an important role in improving the worldwide chickpea yield and production. The combination of Rhizobium and VAM treatments has shown great promise in stimulating nodulation in chickpea plants. These discoveries provide valuable insights that can be instrumental in advancing both chickpea cultivation techniques and strategies for optimizing nitrogen fixation in agricultural systems.
Urine proteome uncover common mechanism between mucopolysaccharidosis type I and II
Authors: Yuan Xiaozhou , Jia Donghao , Wan gefan , Liu kefu , Meng Yan , Duan Jinyan
Published: December 2023

Mucopolysaccharidosis (MPS) type I and II are two types of rare lysosomal storage diseases, which lead to the accumulation of glycosaminoglycans due to the lack of the enzyme alpha-L-iduronidase (IDUA) and iduronate 2-sulfatase (IDS) respectively. There are some similar pathogenic mechanisms and clinical phenotypes but also some specific minute manifestations between these two subtypes. To better understand the similarities in the pathogenesis and clinical symptoms of these two diseases and the mechanism of differential symptoms, we used TMT technology to analyze the differential protein profiles in the urine of MPS I and MPS II patients. We detected the differential proteins of MPS I and MPS II compared with the control group separately. After that, we focused on 227 differentially expressed proteins (DEPs) which showed consistent changes in the urine of both MPS I and MPS II. Parallel reaction monitoring (PRM) analysis verified that up-regulated HEXB and down-regulated HBA1 showed significant difference in the urine of both subtypes. In addition, we found 391 DEPs by comparative analysis of MPS I and MPS II proteomes and found that DHRS2 contributed to the difference between the two subtypes by PRM verification. Therefore, our study demonstrates the value of multi-sample proteomics combined analysis in exploring the similarities and differences of functional proteins between MPS I and MPS II, which provides a new idea for the clinical study of the characteristics of MPS subtypes and the exploration of common treatment options.