bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal Sizing of Battery-Integrated Hybrid Renewable Energy Sources with Ramp Rate Limitations on a Grid Using ALA-QPSO
Authors: Nuvvula Ramakrishna S. S. , Elangovan Devaraj , Teegala Kishore Srinivasa , Madurai Elavarasan Rajvikram , Islam Md. Rabiul , Inapakurthi Ravikiran
Published: August 2021

Higher penetration of variable renewable energy sources into the grid brings down the plant load factor of thermal power plants. However, during sudden changes in load, the thermal power plants support the grid, though at higher ramping rates and with inefficient operation. Hence, further renewable additions must be backed by battery energy storage systems to limit the ramping rate of a thermal power plant and to avoid deploying diesel generators. In this paper, battery-integrated renewable energy systems that include floating solar, bifacial rooftop, and wind energy systems are evaluated for a designated smart city in India to reduce ramping support by a thermal power plant. Two variants of adaptive-local-attractor-based quantum-behaved particle swarm optimization (ALA-QPSO) are applied for optimal sizing of battery-integrated and hybrid renewable energy sources to minimize the levelized cost of energy (LCoE), battery life cycle loss (LCL), and loss of power supply probability (LPSP). The obtained results are then compared with four variants of differential evolution. The results show that out of 427 MW of the energy potential, an optimal set of hybrid renewable energy sources containing 274 MW of rooftop PV, 99 MW of floating PV, and 60 MW of wind energy systems supported by 131 MWh of batteries results in an LPSP of 0.005%, an LCoE of 0.077 USD/kW, and an LCL of 0.0087. A sensitivity analysis of the results obtained through ALA-QPSO is performed to assess the impact of damage to batteries and unplanned load appreciation, and it is found that the optimal set results in more energy sustainability.
Comparison of Optimized and Conventional Models of Passive Solar Greenhouse—Case Study: The Indoor Air Temperature, Irradiation, and Energy Demand
Authors: Mohammadi Saleh , Khalife Esmail , Kaveh Mohammad , Sayyah Amir Hosein Afkari , Nikbakht Ali Mohammad , Szymanek Mariusz , Dziwulski Jacek
Published: August 2021

This study was carried out to optimize a computational model of a new underground passive solar greenhouse to improve thermal performance, storage, and saving of heat solar energy. Optimized and conventional passive solar greenhouse were compared in regards of indoor air temperature, irradiation, and energy demand. Six different materials were used in the conventional model. In addition, TRNSYS software was employed to determine heat demand and irradiation in the greenhouse. The results showed that the annual total heating requirement in the optimized model was 30% lower than a conventional passive solar system. In addition, the resulting average air temperature in the optimized model ranged from −4 to 33.1 °C in the four days of cloud, snow, and sun. The average air temperature in the conventional passive solar greenhouse ranged from −8.4 to 24.7 °C. The maximum monthly heating requirement was 796 MJ/m2 for the Wtype87 model (100-mm lightweight concrete block) and the minimum value was 190 MJ/m2 for the Wtype45 model (50-mm insulation with 200-mm clay tile) in a conventional passive solar greenhouse while the monthly heating requirement estimated 126 MJ/m2 for the optimized greenhouse model. The predictability of the TRNSYS model was calculated with a coefficient of determination (R2) of 95.95%.
Development of a Smart Energy Community by Coupling Neighbouring Community Microgrids for Enhanced Power Sharing Using Customised Droop Control
Authors: Patra Sandipan , Madichetty Sreedhar , Basu Malabika
Published: August 2021

This article aims to develop a smart isolated energy community (EC) by coupling the neighbouring rural community microgrids (CMGs) with enhanced droop control for efficient power sharing. This recommended solution employs a power management (PM) based droop-control to enable independent neighbouring CMGs to share power on an available basis by not constraining CMG inverters to equal power sharing. During the grid-connected mode, the droop control may have different power setpoints of each CMG. However, during the standalone mode of operation, the power setpoint should be defined according to their power rating and availability to maintain the system stability. In this article, a PM strategy is developed to maintain the power setpoints of the autonomous CMGs. An improper selection of power setpoints in autonomous CMG can raise the DC link voltage to an unmanageable value and can cause an inadvertent shutdown of CMG. The suggested PM-based droop control enables the CMG inverter not to restrict the inverter to equal power share but to distribute its active power as available in an asymmetric way, if required. The dynamic performance of the proposed coupled system incorporated with two remote isolated CMGs is investigated in a MATLAB environment. Further, a laboratory prototype of the proposed system has been developed using a LabVIEW-based sbRIO controller to verify the efficacy of the proposed approach.
Numerical Investigation of the Influence of Vegetation on the Aero-Thermal Performance of Buildings with Courtyards in Hot Climates
Authors: Sun Hao , Jimenez-Bescos Carlos , Mohammadi Murtaza , Zhong Fangliang , Calautit John Kaiser
Published: August 2021

Natural ventilation is an energy-efficient way to provide fresh air and enhance indoor comfort levels. The wind-driven natural ventilation in courtyards has been investigated by many researchers, particularly the influence of the spatial configuration and environmental parameters on the ventilation and thermal comfort performance. However, previous research has mainly focused on the courtyard region instead of the indoor spaces surrounding it. Additionally, as a microclimate regulator, courtyards are rarely assessed in terms of the impact of vegetation, including its impact on energy consumption and thermal comfort. Evapotranspiration from vegetation can help lower air temperature in the surrounding environment and, therefore, its influence on the ventilation and thermal comfort in buildings with courtyards should be evaluated. The present study investigates the impact of vegetation on the aero-thermal comfort conditions in a courtyard and surrounding buildings in hot climates. Computational fluid dynamics was employed to evaluate the aero-thermal comfort conditions of the courtyard and surrounding buildings with different configurations of vegetation. The modeling was validated using previous works’ experimental data, and good agreement was observed. Thermal comfort indices were used to assess thermal performance. The study also evaluated the cover, height and planting area of vegetation in the courtyard. The results of this study can help develop tools that can assist the addition of vegetation in courtyards to maximize their effects. Future works will focus on looking at the influence of the strategies on different designs and layouts of courtyards.
Aggregation of Radial Distribution System Bus with Volt-Var Control
Authors: Kikusato Hiroshi , Ustun Taha Selim , Orihara Dai , Hashimoto Jun , Otani Kenji
Published: August 2021

The high penetration of the distributed energy resources (DERs) encourages themselves to implement grid-supporting functions, such as volt-var control. The quasi-static time-series (QSTS) simulation is an essential technique to evaluate the impact of active DERs on the grid. Meanwhile, the increase of complexity on the circuit model causes a heavy computational burden of QSTS simulation. Although circuit reduction methods have been proposed, there have been few methods that can appropriately handle the distribution system (DS) with multiple voltage control devices, such as DERs implementing volt-var control. To address the remaining issues, this paper proposes an offline bus aggregation method for DS with volt-var control. The method determines the volt-var curve for the aggregated bus on the basis of historical data to reduce error in the aggregated model, and its offline process solves the computational convergence issue concerned in the online one. The effectiveness of the proposed method is validated in the simulation using a Japanese low-voltage DS model. The simulation results show that the proposed method can reduce the voltage error and computational time. Furthermore, the versatility of the proposed method is verified to show the performance does not heavily depend on how to select historical data for model-building.
Anaerobic Digestion of Wastewater Sludge and Alkaline-Pretreated Wheat Straw at Semi-Continuous Pilot Scale: Performances and Energy Assessment
Authors: Peyrelasse Christine , Barakat Abdellatif , Lagnet Camille , Kaparaju Prasad , Monlau Florian
Published: August 2021

During the last decade, the application of pretreatment has been investigated to enhance methane production from lignocellulosic biomass such as wheat straw (WS). Nonetheless, most of these studies were conducted in laboratory batch tests, potentially hiding instability problems or inhibition, which may fail in truly predicting full-scale reactor performance. For this purpose, the effect of an alkaline pretreatment on process performance and methane yields from WS (0.10 g NaOH g−1 WS at 90 °C for 1 h) co-digested with fresh wastewater sludge was evaluated in a pilot-scale reactor (20 L). Results showed that alkaline pretreatment resulted in better delignification (44%) and hemicellulose solubilization (62%) compared to untreated WS. Pilot-scale study showed that the alkaline pretreatment improved the methane production (261 ± 3 Nm3 CH4 t−1 VS) compared to untreated WS (201 ± 6 Nm3 CH4 t−1 VS). Stable process without any inhibition was observed and a high alkalinity was maintained in the reactor due to the NaOH used for pretreatment. The study thus confirms that alkaline pretreatment is a promising technology for full-scale application and could improve the overall economic benefits for biogas plant at 24 EUR t−1 VS treated, improve the energy recovery per unit organic matter, reduce the digestate volume and its disposal costs.
A Novel Sooty Terns Algorithm for Deregulated MPC-LFC Installed in Multi-Interconnected System with Renewable Energy Plants
Authors: Ali Hossam Hassan , Fathy Ahmed , Al-Shaalan Abdullah M. , Kassem Ahmed M. , M. H. Farh Hassan , Al-Shamma’a Abdullrahman A. , A. Gabbar Hossam
Published: August 2021

This paper introduces a novel metaheuristic approach of sooty terns optimization algorithm (STOA) to determine the optimum parameters of model predictive control (MPC)-based deregulated load frequency control (LFC). The system structure consists of three interconnected plants with nonlinear multisources comprising wind turbine, photovoltaic model with maximum power point tracker, and superconducting magnetic energy storage under deregulated environment. The proposed objective function is the integral time absolute error (ITAE) of the deviations in frequencies and powers in tie-lines. The analysis aims at determining the optimum parameters of MPC via STOA such that ITAE is minimized. Moreover, the proposed STOA-MPC is examined under variation of the system parameters and random load disturbance. The time responses and performance specifications of the proposed STOA-MPC are compared to those obtained with MPC optimized via differential evolution, intelligent water drops algorithm, stain bower braid algorithm, and firefly algorithm. Furthermore, a practical case study of interconnected system comprising the Kuraymat solar thermal power station is analyzed based on actual recorded solar radiation. The obtained results via the proposed STOA-MPC-based deregulated LFC confirmed the competence and robustness of the designed controller compared to the other algorithms.
Operation Method of a Load Test Device Using an Energy Storage System for Site Acceptance Test of a Fire-Fighting Emergency Generator
Authors: Jin Juan , Choi Seung-Kyou
Published: August 2021

Emergency generators are important facilities that supply emergency power to fire-fighting facilities in the event of a power outage. Accordingly, a load test of the emergency generator should be performed by cutting off the power source of the fire-fighting target in order to accurately confirm the performance and condition of the emergency generator in normal circumstances. However, the test has usually been carried out without loads due to serious problems, which are caused by a shutdown of the power source for the load test of emergency generators, such as the shutdown of emergency load, etc. In order to overcome these problems, this paper proposes an operation method and algorithm of a load test device using ESS, which can conform to characteristics of emergency loads installed in fire-fighting targets by interconnecting it with the emergency generator. In addition, this paper performs a modeling of an emergency power system using PSCAD/EMTDC, and then this paper confirms the usefulness of the proposed method and operation algorithm of the load test device using ESS.
The Architecture of a Real-Time Control System for Heating Energy Management in the Intelligent Building
Authors: Prusak Daniel , Karpiel Grzegorz , Kułakowski Konrad
Published: August 2021

Very often, constructors and designers of intelligent building and building automation systems have a choice: to create a compact system with a limited configuration and modifying the system’s behavior possibilities or provide a fully configurable solution at the expense of introducing a full SCADA system equipped with an additional knowledge database and inference system equipped with learning capabilities. In the presented work, we show that there is a third solution. Using a multilayer control system composed of programmable FPGAs, small PCs, and cloud computing resources, we can design and implement a fully configurable intelligent control system for the building’s heating. Our solution combines the compactness of the structure and the ease of installation and assembly.
Comprehensive Evaluation Method of Historical Timber Structural Building Taking Fujiu Zhou House as an Example
Authors: Wang Peixuan , Li Shengcai , Macchioni Nicola , Palanti Sabrina , Milani Gabriele
Published: August 2021

Physical and mechanical properties of timber components are the basis of developing the technical measures for the conservation and restoration of historical timber structural buildings. By means of integrating on-site investigation (such as a visual survey, moisture content test, micro-drilling resistance test, and material samples collection of historical timber components) and laboratory tests, this study proposed a series of methodologies for comprehensively evaluating the physical and mechanical properties of timber. This method can be quickly mastered by various non-professionals and can help the cross-learning of various disciplines engaged in the research of architectural heritage protection. As a trial, the methodologies were applied to survey and assess a typical historical Chinese timber structural building named the Fujiu Zhou house (the house is located in No. 19, Qinglian lane, Yangzhou city, Jiangsu province, China). The paper studies the 224 components of the main structure of the building, including 128 columns and 96 beams. With the help of the components’ defects and damage status, GB/T13942.2-1992 and the National Lumber Grades Authority (NLGA), the grade of timber components was distinguished. The modulus of elasticity (MOE), modulus of rupture (MOR), and other related material properties parameters of timber components were also obtained. The trial results verify that the proposed methodologies are reasonable, and they can be helpful for the conservation of a historical timber structural building.
The Role of Verbal Aggression in Cyberbullying Perpetration and Victimization by Middle School Students
Authors: Eden Jen , Roberto Anthony J.
Published: August 2021

This manuscript examined the role trait verbal aggression plays in cyberbullying victimization and perpetration in adolescence. More than 400 middle school students (46.8% males and 52.2% females) completed a questionnaire on trait verbal aggression and their history of cyberbullying perpetration and victimization. Linear regression analyses revealed that trait verbal aggression was a statistically significant predictor of both cyberbullying perpetration and victimization, that cyberbullying perpetration and cyberbullying victimization are related, and that cyberbullying perpetration appears to increase with age, while cyberbullying victimization does not. Ideas and implications for future applications of verbal aggression and cyberbullying are discussed.
Megalos: A Scalable Architecture for the Virtualization of Large Network Scenarios
Authors: Scazzariello Mariano , Ariemma Lorenzo , Di Battista Giuseppe , Patrignani Maurizio
Published: August 2021

We introduce an open-source, scalable, and distributed architecture, called Megalos, that supports the implementation of virtual network scenarios consisting of virtual devices (VDs) where each VD may have several Layer 2 interfaces assigned to virtual LANs. We rely on Docker containers to realize vendor-independent VDs and we leverage Kubernetes for the management of the nodes of a distributed cluster. Our architecture does not require platform-specific configurations and supports a seamless interconnection between the virtual environment and the physical one. Also, it guarantees the segregation of each virtual LAN traffic from the traffic of other LANs, from the cluster traffic, and from Internet traffic. Further, a packet is only sent to the cluster node containing the recipient VD. We produce several example applications where we emulate large network scenarios, with thousands of VDs and LANs. Finally, we experimentally show the scalability potential of Megalos by measuring the overhead of the distributed environment and of its signaling protocols.
Flavors of Non-Random Meiotic Segregation of Autosomes and Sex Chromosomes
Authors: Pajpach Filip , Wu Tianyu , Shearwin-Whyatt Linda , Jones Keith , Grützner Frank
Published: August 2021

Segregation of chromosomes is a multistep process occurring both at mitosis and meiosis to ensure that daughter cells receive a complete set of genetic information. Critical components in the chromosome segregation include centromeres, kinetochores, components of sister chromatid and homologous chromosomes cohesion, microtubule organizing centres, and spindles. Based on the cytological work in the grasshopper Brachystola, it has been accepted for decades that segregation of homologs at meiosis is fundamentally random. This ensures that alleles on chromosomes have equal chance to be transmitted to progeny. At the same time mechanisms of meiotic drive and an increasing number of other examples of non-random segregation of autosomes and sex chromosomes provide insights into the underlying mechanisms of chromosome segregation but also question the textbook dogma of random chromosome segregation. Recent advances provide a better understanding of meiotic drive as a prominent force where cellular and chromosomal changes allow autosomes to bias their segregation. Less understood are mechanisms explaining observations that autosomal heteromorphism may cause biased segregation and regulate alternating segregation of multiple sex chromosome systems or translocation heterozygotes as an extreme case of non-random segregation. We speculate that molecular and cytological mechanisms of non-random segregation might be common in these cases and that there might be a continuous transition between random and non-random segregation which may play a role in the evolution of sexually antagonistic genes and sex chromosome evolution.
Progress in Research on the Mechanisms Underlying Chloroplast-Involved Heat Tolerance in Plants
Authors: Zeng Chu , Jia Ting , Gu Tongyu , Su Jinling , Hu Xueyun
Published: August 2021

Global warming is a serious challenge plant production has to face. Heat stress not only affects plant growth and development but also reduces crop yield and quality. Studying the response mechanisms of plants to heat stress will help humans use these mechanisms to improve the heat tolerance of plants, thereby reducing the harm of global warming to plant production. Research on plant heat tolerance has gradually become a hotspot in plant molecular biology research in recent years. In view of the special role of chloroplasts in the response to heat stress in plants, this review is focusing on three perspectives related to chloroplasts and their function in the response of heat stress in plants: the role of chloroplasts in sensing high temperatures, the transmission of heat signals, and the improvement of heat tolerance in plants. We also present our views on the future direction of research on chloroplast related heat tolerance in plants.
Bardet–Biedl Syndrome—Multiple Kaleidoscope Images: Insight into Mechanisms of Genotype–Phenotype Correlations
Authors: Florea Laura , Caba Lavinia , Gorduza Eusebiu Vlad
Published: August 2021

Bardet–Biedl Syndrome is a rare non-motile primary ciliopathy with multisystem involvement and autosomal recessive inheritance. The clinical picture is extremely polymorphic. The main clinical features are retinal cone-rod dystrophy, central obesity, postaxial polydactyly, cognitive impairment, hypogonadism and genitourinary abnormalities, and kidney disease. It is caused by various types of mutations, mainly in genes encoding BBSome proteins, chaperonins, and IFT complex. Variable expressivity and pleiotropy are correlated with the existence of multiple genes and variants modifiers. This review is focused on the phenomena of heterogeneity (locus, allelic, mutational, and clinical) in Bardet–Biedl Syndrome, its mechanisms, and importance in early diagnosis and proper management.
Highly Conservative Pattern of Sex Chromosome Synapsis and Recombination in Neognathae Birds
Authors: Torgasheva Anna , Malinovskaya Lyubov , Zadesenets Kira S. , Slobodchikova Anastasia , Shnaider Elena , Rubtsov Nikolai , Borodin Pavel
Published: August 2021

We analyzed the synapsis and recombination between Z and W chromosomes in the oocytes of nine neognath species: domestic chicken Gallus gallus domesticus, grey goose Anser anser, black tern Chlidonias niger, common tern Sterna hirundo, pale martin Riparia diluta, barn swallow Hirundo rustica, European pied flycatcher Ficedula hypoleuca, great tit Parus major and white wagtail Motacilla alba using immunolocalization of SYCP3, the main protein of the lateral elements of the synaptonemal complex, and MLH1, the mismatch repair protein marking mature recombination nodules. In all species examined, homologous synapsis occurs in a short region of variable size at the ends of Z and W chromosomes, where a single recombination nodule is located. The remaining parts of the sex chromosomes undergo synaptic adjustment and synapse non-homologously. In 25% of ZW bivalents of white wagtail, synapsis and recombination also occur at the secondary pairing region, which probably resulted from autosome−sex chromosome translocation. Using FISH with a paint probe specific to the germline-restricted chromosome (GRC) of the pale martin on the oocytes of the pale martin, barn swallow and great tit, we showed that both maternally inherited songbird chromosomes (GRC and W) share common sequences.
Pushing the Boundaries: Forensic DNA Phenotyping Challenged by Single-Cell Sequencing
Authors: Diepenbroek Marta , Bayer Birgit , Anslinger Katja
Published: August 2021

Single-cell sequencing is a fast developing and very promising field; however, it is not commonly used in forensics. The main motivation behind introducing this technology into forensics is to improve mixture deconvolution, especially when a trace consists of the same cell type. Successful studies demonstrate the ability to analyze a mixture by separating single cells and obtaining CE-based STR profiles. This indicates a potential use of the method in other forensic investigations, like forensic DNA phenotyping, in which using mixed traces is not fully recommended. For this study, we collected single-source autopsy blood from which the white cells were first stained and later separated with the DEPArray™ N×T System. Groups of 20, 10, and 5 cells, as well as 20 single cells, were collected and submitted for DNA extraction. Libraries were prepared using the Ion AmpliSeq™ PhenoTrivium Panel, which includes both phenotype (HIrisPlex-S: eye, hair, and skin color) and ancestry-associated SNP-markers. Prior to sequencing, half of the single-cell-based libraries were additionally amplified and purified in order to improve the library concentrations. Ancestry and phenotype analysis resulted in nearly full consensus profiles resulting in correct predictions not only for the cells groups but also for the ten re-amplified single-cell libraries. Our results suggest that sequencing of single cells can be a promising tool used to deconvolute mixed traces submitted for forensic DNA phenotyping.
δ13C and δD Values of n-Alkanes from In-Reservoir Biodegraded Oils: Implications for Understanding the Mechanisms of Biodegradation and for Petroleum Exploration
Authors: Pedentchouk Nikolai , Bennett Barry , Larter Steve
Published: August 2021

This study investigates the magnitude and direction of stable C and H isotope shifts of n-C15–30 alkanes from biodegraded oils sourced from Type II (Oil suite S) and Type II/III (Oil suite H) kerogens. Compound-specific isotope data show a 2.0‰ 13C-enrichment and no D-enrichment of n-alkanes in the most biodegraded oil from sample suite S. Similarly, there is a 1.5–2.5‰ 13C-enrichment and no D-enrichment in Oil suite H. Overall, there is a <2.5‰ δ13C and <20‰ δD variability among individual n-alkanes in the whole sequence of biodegradation. N-alkanes from the least biodegraded Oil H samples are 2–4‰ 13C-enriched in comparison with the least biodegraded Oil S. However, there are no differences in the δD values of n-alkanes in these samples. Our indirect isotopic evidence suggests (1) a site-specific biodegradation process, most likely at position C-2 and/or C-3 or another site-specific process, and (2) a significant D/H exchange between organic compounds in the source rock and isotopically similar marine formation waters. We conclude that, unlike δD methodology, investigation of δ13C composition of n-alkanes has strong potential as a supplementary tool for oil–oil and oil–source-rock correlation even in biodegraded oils when n-alkanes are present.
The Effect of Physical and Mental Health and Health Behavior on the Self-Rated Health of Pregnant Women
Authors: Lee Eunwon , Song Jiyoung
Published: August 2021

Self-rated health (SRH) is an evaluation tool to assess an individual’s level of health, including both general health and personal experience. There have been existing studies on women’s SRH; however, few studies have been on pregnant women’s SRH and its associated factors. This study investigated the SRH of pregnant women and their factors using the Korea Community Health Survey. The chi-squared test and multivariable logistic regression were used to investigate the effects of demographic, physical, and mental health and health behaviors on the SRH of pregnant women. As a result of the study, 54.0% out of 1032 pregnant women had good SRH. Their SRH score was good when they were young, economically active, and living in cities. Poor SRH was observed with depression, hypertension, and after experiencing a fall. Good SRH was found when they exercised and slept for more than 8 h a day. This study is the first to observe the SRH of pregnant women and its related factors in South Korea.
Longitudinal Distress among Brazilian University Workers during Pandemics
Authors: Zibetti Murilo Ricardo , Serralta Fernanda Barcellos , Evans Chris
Published: August 2021

The present study aimed to examine changes in mental distress in Brazilian university workers during the pandemic. All workers (n ≃ 1850) of an institution were invited to respond to a survey that took place in three stages, with collections in May (n = 407), June/July (n = 258), and August (n = 207) 2020, and included questions on demographic, health, general and psychological support, and psychometric assessment of mental distress (Clinical Outcome Routine Evaluation- CORE-OM) combined with an open question about major concerns. The results of the Multilevel Modeling analysis pointed to the absence of significant differences across the repeated measures of distress. The only variable associated with increased psychological distress over time was a lower level of support for household chores. Qualitative analysis of the reported major concerns was carried out with a sub-sample who showed reliable deterioration in CORE-OM across time (n = 17). The diversity of concerns reported by this group reinforced that work–life imbalance contributes to mental distress of university workers during the pandemic. Low response rate, although not unexpected due to the circumstances, limits the generalization of findings. The present data suggest that in addition to issues related to contagion and specific restricted measures to contain the spread of the disease, the personal reorganization of life required to maintain activities at home and work can be an important contributor to pandemic-related psychological distress.
Cognitive Remediation in Virtual Environments for Patients with Schizophrenia and Major Depressive Disorder: A Feasibility Study
Authors: Plechatá Adéla , Hejtmánek Lukáš , Bednářová Martina , Fajnerová Iveta
Published: August 2021

Standard approaches to cognitive remediation can suffer from limited skill transferability to patients’ life. Complex virtual environments (VEs) enable us to create ecologically valid remediation scenarios while preserving laboratory conditions. Nevertheless, the feasibility and efficacy of these programs in psychiatric patients are still unknown. Our aim was to compare the feasibility and efficacy of a novel rehabilitation program, designed in complex VEs, with standard paper–pencil treatment in patients with schizophrenia and major depressive disorder. We recruited 35 participants to complete a VE rehabilitation program and standard treatment in a crossover pilot study. Twenty-eight participants completed at least one program, 22 were diagnosed with schizophrenia and 6 with major depressive disorder. Participant’s performance in the representative VE training task significantly improved in terms of maximum achieved difficulty (p ≤ 0.001), speed (p < 0.001) and efficacy (p ≤ 0.001) but not in item performance measure. Neither the standard treatment nor the VE program led to improvement in standardized cognitive measures. Participants perceived both programs as enjoyable and beneficial. The refusal rate was higher in the VE program (8.6%) than in the standard treatment (0%). But in general, the VE program was well-accepted by the psychiatric patients and it required minimal involvement of the clinician due to automatic difficulty level adjustment and performance recording. However, the VE program did not prove to be effective in improving cognitive performance in the standardized measures.
A Huge Plantar Intramuscular Hemangioma in the Plantar Area Treated Surgically: A Case Report and Literature Review
Authors: Lee Hong Seop , Hong Yong Cheol , Jung Ki Jin , Yeo Eui Dong , Won Sung Hun , Jang Si-Hyong , Ji Jae Young , Lee Dhong Won , Yoon Sung Joon , Kim Woo Jong
Published: August 2021

Intramuscular hemangioma (IH) is rare, accounting for only 0.8% of all hemangioma cases. In particular, IH of the foot has only been reported a few times. In such cases, the symptoms typically include tenderness and swelling, often in relation to physical activity, but tingling or impaired function may also be present. Here, we report a patient who presented with a significant IH in the plantar area treated surgically. A 25-year-old female visited our hospital with pain in the plantar aspect of the right foot. She had noticed a mass about 10 years prior. She had previously experienced pain only when pressing the mass, but the pain subsequently became more regular pain and was exacerbated by exercise. In fact, the pain became so intense that she could not sleep well. Upon physical examination, mild swelling and tenderness of the plantar area were noted in the second to the fourth metatarsal. Sensation and motor reflexes were normal and the results of Tinel’s test were negative. Plain radiographs of the right foot revealed phleboliths scattered throughout the first to third intermetatarsal spaces. Magnetic resonance imaging revealed a space-occupying multilobulated mass (5.6 × 2.8 × 2.5 cm) located in the flexor digitorum brevis (FDB) muscle, which penetrated the plantar fascia and spread to the subcutaneous layer. In T2-weighted images, the lesion displayed a hyperintense signal compared to the surrounding skeletal muscle. Based on radiological findings, we suspected IH. The mass surrounded by the FDB muscle was exposed and completely removed via wide excision. IH consisting of cavernous-like vascular structures was diagnosed on pathology. At 1-year follow-up, the patient was almost asymptomatic and had recovered almost full range of motion in the plantar area. Histological analysis and surgery are recommended to remove intramuscular hemangiomas in the plantar area, but if the patient is not suitable for surgery, sclerotherapy or combination treatment should also be considered.
Perspective Developing Successful Collaborative Research Partnerships with AI/AN Communities
Authors: Credo Jonathan , Ingram Jani C.
Published: August 2021

In the United States, American Indian and Alaska Native (AI/AN) people are frequently under- or misrepresented in research and health statistics. A principal reason for this disparity is the lack of collaborative partnerships between researchers and tribes. There are hesitations from both academic Western scientists and tribal communities to establish new partnerships due to differences in cultural and scientific understanding, from data ownership and privacy to dissemination and project expansion. An infamous example is the mishandling of samples collected from the Havasupai Tribe by Arizona State University (ASU) scientists, leading to a legal battle between the tribe and ASU and ending in a moratorium of research with the Havasupai people. This paper will explore three successful and positive collaborations with a large and small tribe, including how the partnerships were established and the outcomes of the collaboration. In addition, the paper will provide perspective of what needs to be addressed by Western scientists if productive collaborations with tribal groups are to be established.
The Effect of a Brief, Web-Based Animated Video for Improving Comprehension and Implementation Feasibility for Reducing Anterior Cruciate Ligament Injury: A Three-Arm Randomized Controlled Trial
Authors: Petushek Erich J. , Mørtvedt Anne Inger , Nelson Brittany L. , Hamati Mary C.
Published: August 2021

Neuromuscular injury prevention training (IPT) has been shown to reduce anterior cruciate ligament (ACL) injury risk by approximately 50%, but the implementation rate is low. One of the most important modifiable barriers for implementation is coaches’ comprehension of risk and intervention strategies. This study aimed to evaluate the effect of a brief, web-based, animated video on ACL injury prevention comprehension and IPT implementation feasibility. Coaches in landing and cutting sports were recruited and randomized into three groups. (1) Intervention: brief multimedia animated video about ACL injury and prevention. (2) Active control: commonly accessed, text-based web resource about ACL injury and prevention. (3) Placebo control: brief multimedia video about concussions. Overall ACL comprehension—composed of basic ACL knowledge, risk knowledge, prevention knowledge, and severity knowledge—as well as implementation feasibility were all measured prior to and immediately following the interventions. Overall ACL comprehension improved the most in the animated video group (Cohen’s d = 0.86) and, to a lesser degree, in the active control web-based article group (Cohen’s d = 0.39). Both video and web-based article groups had greater implementation feasibility compared to the control group (p = 0.01). Overall, these initial results suggest that a brief, web-based, animated video has the potential to be a superior method for informing stakeholders in order to reduce traumatic injuries in sport.
Analysis of Risk Factors for Major Complications of 1500 Transvenous Lead Extraction Procedures with Especial Attention to Tricuspid Valve Damage
Authors: Tułecki Łukasz , Polewczyk Anna , Jacheć Wojciech , Nowosielecka Dorota , Tomków Konrad , Stefańczyk Paweł , Kosior Jarosław , Duda Krzysztof , Polewczyk Maciej , Kutarski Andrzej
Published: August 2021

Background: Transvenous lead extraction (TLE) is a relatively safe procedure, but it may cause severe complications such as cardiac/vascular wall tear (CVWT) and tricuspid valve damage (TVD). Methods: The risk factors for CVWT and TVD were examined based on an analysis of data of 1500 extraction procedures performed in two high-volume centers. Results: The total number of major complications was 33 (2.2%) and included 22 (1.5%) CVWT and 12 (0.8%) TVD (with one case of combined complication). Patients with hemorrhagic complications were younger, more often women, less often presenting low left ventricular ejection fraction (LVEF) and those who received their first cardiac implantable electronic device (CIED) earlier than the control group. A typical patient with CVWT was a pacemaker carrier, having more leads (including abandoned leads and excessive loops) with long implant duration and a history of multiple CIED-related procedures. The risk factors for TVD were similar to those for CVWT, but the patients were older and received their CIED about nine years earlier. Any form of tissue scar and technical problems were much more common in the two groups of patients with major complications. Conclusions: The risk factors for CVWT and TVD are similar, and the most important ones are related to long lead dwell time and its consequences for the heart (various forms of fibrotic scarring). The occurrence of procedural complications does not affect long-term survival in patients undergoing lead extraction.
Application of Modern Clinical Risk Scores in the Global Assessment of Risks Related to the Diagnosis and Treatment of Acute Coronary Syndromes in Everyday Medical Practice
Authors: Gawinski Lukasz , Engelseth Per , Kozlowski Remigiusz
Published: August 2021

This article presents an overview of contemporary risk assessment systems used in patients with myocardial infarction. The full range of risk scales, both recommended by the European Society of Cardiology and others published in recent years, is presented. Scales for assessing the risk of ischemia/death as well as for assessing the risk of bleeding are presented. A separate section is devoted to systems assessing the integrated risk associated with both ischemia and bleeding. In the first part of the work, each of the risk scales is described in detail, including the clinical trials/registers on the basis of which they were created, the statistical methods used to develop them, as well as the specification of their individual parameters. The next chapter presents the practical application of a given scale in the patient risk assessment process, the timing of its application on the timeline of myocardial infarction, as well as a critical assessment of its potential advantages and limitations. The last part of the work is devoted to the presentation of potential directions for the development of risk assessment systems in the future.
Impact of Urbanization on the Environmental Regulation Efficiency in the Yangtze River Basin Based on the Empirical Analysis of Spatial Econometrics
Authors: Zhang Qian , Tang Decai , Bethel Brandon J.
Published: August 2021

Urbanization has been positioned as an important driving force for economic development. This article examines the impact of urbanization on environmental regulation efficiency (ERE) in the Yangtze River Basin (YRB). Based on a panel dataset of 97 cities in the YRB from 2005 to 2016, a spatial econometric model was used for analysis. Results show that the average ERE in the YRB is relatively low and manifests in the shape of a curved smile. The urbanization level of the permanent population is far lower than the average level of developed countries. However, the urbanization level is showing a steady growth trend. During this period, ERE in the Yangtze River middle, upper, and lower reaches was measured at 0.77, 0.58, and 0.52, respectively. The urbanization rate was measured at 0.59, 0.45, and 0.39, in the lower, middle, and upper reaches, respectively. When only considering population urbanization, the previously observed negative correlation between ERE and the Kuznets curve disappears. However, if the carrying capacity of economic activities is considered, the U-shaped relationship between urbanization rate and ERE returns. The environmental Kuznets curve is consequently verified. In addition, there is an inverted U-shaped nonlinear relationship between economic development and ERE. The results of this article show that there are unsustainable risks in the rapid pursuit of population urbanization. Only by improving the quality of urbanization and adapting the level of urbanization to the carrying capacity of resources and environment can we truly promote high-quality economic development. The article puts forward some suggestions to promote the green development of the economy.
The Impact of FDI on Urban PM2.5 Pollution in China: The Mediating Effect of Industrial Structure Transformation
Authors: Pei Taowu , Gao Lei , Yang Chao , Xu Chang , Tian Yu , Song Weiming
Published: August 2021

With the rapid growth of foreign direct investment (FDI), PM2.5 pollution in Chinese cities is increasing. Based on panel data for 271 Chinese cities from 2003 to 2016, this paper uses the dynamic spatial fixed-effects Durbin model to analyze the correlation between FDI and PM2.5 pollution and the effect of FDI on urban PM2.5 concentrations, as mediated by industrial structure transformation, which is clarified using Stata/SE 16.0. The results showed that PM2.5 pollution in China has significant spatial spillover effects, and the pollution haven hypothesis is applicable to Chinese cities. The industrial structure partially mediates the relationship between FDI and PM2.5. This paper proposes that local governments should promote the market-oriented reform of FDI to create a more convenient, legalized, and international environment for FDI and innovate the governance philosophy of only reducing the existing emissions. A top-level design and sound market supervision system of PM2.5 control are also needed.
Understanding the Acceptability and Uptake of HPV Self-Sampling Amongst Women Under- or Never-Screened for Cervical Cancer in Toronto (Ontario, Canada): An Intervention Study Protocol
Authors: Lofters Aisha , Devotta Kimberly , Prakash Vijayshree , Vahabi Mandana
Published: August 2021

Cervical cancer remains a global public health concern, even though scientific advancements have made the disease almost entirely preventable. With the link between human papillomavirus (HPV) and cervical cancer, and the subsequent improvement in screening technology, there is potential to improve access and coverage of cervical screening with the introduction of HPV self-sampling. In Ontario, Canada, a province with a cytology-based screening program (i.e., Pap test), women who identify as South Asian, West Asian, Middle Eastern and North African have some of the lowest rates of screening, and research suggests they have a higher burden of cervical cancer. In this study, we will use both quantitative and qualitative methods to understand the acceptability and uptake of a take-home HPV self-sampling kit. Working with community champions—people with pre-existing connections with local groups—we will recruit women from these groups who are under- or never-screened for cervical cancer. Women will self-select whether they are in the group that tries HPV self-sampling or in the group that does not. We will aim for 100 women in each group. All participants will provide feedback on the feasibility, acceptability and preferences for cervical screening through a survey and phone follow-up. Women who self-select the HPV self-sampling group, will be followed up to find out if they followed through with self-sampling and to understand their experience using the device. Women who do not want to try self-sampling will be followed up to see if they went on to get a Pap test. The qualitative phase of this study consists of five focus groups with participants and semi-structured interviews with key informants in the community.
Analyzing the Impact of COVID-19 Trauma on Developing Post-Traumatic Stress Disorder among Emergency Medical Workers in Spain
Authors: Martínez-Caballero Carmen M. , Cárdaba-García Rosa M. , Varas-Manovel Rocío , García-Sanz Laura M. , Martínez-Piedra Jorge , Fernández-Carbajo Juan J. , Pérez-Pérez Lucía , Madrigal-Fernández Miguel A. , Barba-Pérez M. Ángeles , Olea Elena , Durantez-Fernández Carlos , Herrero-Frutos M. Teresa
Published: August 2021

The early stages of the COVID-19 pandemic presented the characteristics of a traumatic event that could trigger post-traumatic stress disorder. Emergency Medical Services workers are already a high-risk group due to their professional development. The research project aimed to analyse the impact of the COVID-19 pandemic on EMS professionals in terms of their mental health. For this purpose, we present a descriptive crosssectional study with survey methodology. A total of 317 EMS workers (doctors, nurses, and emergency medical technicians) were recruited voluntarily. Psychological distress, post-traumatic stress disorder, and insomnia were assessed. The instruments were the General Health Questionnaire-12 (GHQ-12), the Davidson Trauma Scale (DTS-8), and the Athens Insomnia Scale (AIS-8). We found that 36% of respondents had psychological distress, 30.9% potentially had PTSD, and 60.9% experienced insomnia. Years of work experience were found to be positively correlated, albeit with low effect, with the PTSD score (r = 0.133). Finally, it can be stated that the COVID-19 pandemic has been a traumatic event for EMS workers. The number of professionals presenting psychological distress, possible PTSD, or insomnia increased dramatically during the early phases of the pandemic. This study highlights the need for mental health disorder prevention programmes for EMS workers in the face of a pandemic.
ACTN3 Genotypes and Their Relationship with Muscle Mass and Function of Kosovan Adults
Authors: Boshnjaku Arben , Krasniqi Ermira , Tschan Harald , Wessner Barbara
Published: August 2021

Maintaining muscle mass and function is important throughout the lifestyle. While environmental factors such as physical activity and healthy nutrition are well investigated, the contribution of genetic factors is still controversial. Therefore, we aimed to investigate the impact of a common ACTN3 polymorphism (rs1815739) on body composition, handgrip strength, knee extensor peak torque, and physical performance (gait speed, 30-s arm curl, 30-s chair stand) in Kosovan adults. In total, 308 participants (160 females and 148 males, age range from 40 to 91 years) took part in this cross-sectional study. Genomic DNA was extracted from saliva and assessed for ACTN3 genotype distribution (41.5% of RR, 53.9% of RX and 4.6% of XX). Genotype allocation did not account for differences in any of the variables. Interestingly, female XX carriers were taller (p = 0.025) and had a higher isokinetic knee extension peak torque (p = 0.024) than the RX+RR group. In males, XX carriers were also taller (p = 0.049) and had a lower BMI (p = 0.026), but did not differ in any of the strength and performance parameters. These results indicate that the ACTN3 R577X polymorphism might exert a sex-specific impact on knee extensor peak torque and BMI.