bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficiency of Indian banks with non-performing assets: evidence from two-stage network DEA
Authors: Hafsal K. , Suvvari Anandarao , Durai S. Raja Sethu
Published: July 2020

This paper addresses the concerns regarding the sustainability of the banking sector in India prompted by the recent unintended high level of non-performing assets (NPAs). It uncovers the linkage between NPAs and banking efficiency by integrating NPAs into the measurement of bank efficiency to provide a holistic efficiency profile of the Indian banking sector. We apply the general two-stage data envelopment analysis of Kao [16] by incorporating NPAs as an exogenous output from the first stage, and the empirical results identify an efficiency gap of 16.2% due to NPAs in the Indian banking sector for the year 2016. Further, it also documents that the efficiency gap/loss is increasing over the years and differs according to the shareholding pattern of the banks.
HLA-Arena: A Customizable Environment for the Structural Modeling and Analysis of Peptide-HLA Complexes for Cancer Immunotherapy
Authors: Antunes Dinler A. , Abella Jayvee R. , Hall-Swan Sarah , Devaurs Didier , Conev Anja , Moll Mark , Lizée Gregory , Kavraki Lydia E.
Published: July 2020

PURPOSE

HLA protein receptors play a key role in cellular immunity. They bind intracellular peptides and display them for recognition by T-cell lymphocytes. Because T-cell activation is partially driven by structural features of these peptide-HLA complexes, their structural modeling and analysis are becoming central components of cancer immunotherapy projects. Unfortunately, this kind of analysis is limited by the small number of experimentally determined structures of peptide-HLA complexes. Overcoming this limitation requires developing novel computational methods to model and analyze peptide-HLA structures.

METHODS

Here we describe a new platform for the structural modeling and analysis of peptide-HLA complexes, called HLA-Arena, which we have implemented using Jupyter Notebook and Docker. It is a customizable environment that facilitates the use of computational tools, such as APE-Gen and DINC, which we have previously applied to peptide-HLA complexes. By integrating other commonly used tools, such as MODELLER and MHCflurry, this environment includes support for diverse tasks in structural modeling, analysis, and visualization.

RESULTS

To illustrate the capabilities of HLA-Arena, we describe 3 example workflows applied to peptide-HLA complexes. Leveraging the strengths of our tools, DINC and APE-Gen, the first 2 workflows show how to perform geometry prediction for peptide-HLA complexes and structure-based binding prediction, respectively. The third workflow presents an example of large-scale virtual screening of peptides for multiple HLA alleles.

CONCLUSION

These workflows illustrate the potential benefits of HLA-Arena for the structural modeling and analysis of peptide-HLA complexes. Because HLA-Arena can easily be integrated within larger computational pipelines, we expect its potential impact to vastly increase. For instance, it could be used to conduct structural analyses for personalized cancer immunotherapy, neoantigen discovery, or vaccine development.
Assessing Genitourinary Cancer Clinical Trial Accrual Sufficiency Using Archived Trial Data
Authors: Stensland Kristian , Kaffenberger Samuel , Canes David , Galsky Matthew , Skolarus Ted , Moinzadeh Alireza
Published: July 2020

PURPOSE

Clinical trials often fail to reach their anticipated end points, most frequently because of poor accrual. Prior studies have analyzed trial termination, but it has not been easy to assess accrual estimates using international databases such as ClinicalTrials.gov because of limitations in accessing accrual information. Specifically, it is not easy to extract both anticipated and actual accrual of clinical trials. We designed a new algorithmic approach to extracting trial accrual data from ClinicalTrials.gov and used it to estimate the sufficiency of patient accrual onto genitourinary (GU) cancer trials.

METHODS

We queried ClinicalTrials.gov for completed/terminated phase II and III clinical trials for prostate, bladder, kidney, testicular, and ureteral cancers registered after 2007. We extracted trial characteristics from available XML files. We then used a Python algorithm to access prior trial registrations on the ClinicalTrials.gov archive site and extract both anticipated and actual accrual numbers. We then compared the actual accrual of each trial to its anticipated accrual and defined sufficient accrual as 85% of anticipated accrual.

RESULTS

The algorithm was 100% accurate compared with hand extraction in a small validation subset. A total of 925 trials were included, of which 840 (91%) had both anticipated and actual accrual. Only 418 (50%) trials had sufficient accrual (≥ 85% of anticipated). Considering only trials marked as successfully completed, 395/597 (66%) reached sufficient accrual.

CONCLUSION

GU cancer trials often do not meet their anticipated accrual goals. New approaches to trial conduct are direly needed. Our reproducible and scalable approach to extracting accrual information can be applied to analysis of ClinicalTrials.gov in future analyses in the hope of improving the efficiency of the clinical trials enterprise.
Tomosynthesis-guided breast and axillary localizations: tips and tricks
Authors: Choudhery Sadia , Anderson Tara
Published: July 2020

As tomosynthesis is rapidly adopted by breast imaging practices, tomosynthesis-guided procedures are increasingly being performed. Tomosynthesis-guided needle localizations are feasible and efficient and allow for localization of tomosynthesis-only findings or one-view findings, which may be difficult to localize under standard digital mammography. In this review, we describe our step-by-step approach for performing tomosynthesis-guided localizations of the breast and axilla using a standard tomosynthesis unit.
Rola języka w uwalnianiu się z dziedzicznych traum
Authors: Marcol Katarzyna
Published: July 2020

The Role of Language in Releasing from Inherited Traumas. Negotiations of the Social Position of the Silesian Minority in Serbian Banat

The aim of the paper is to show the dependence between language, collective memory (also post-memory) and sense of identity. This issue is analysed using the example of an ethnic minority living in the village of Ostojićevo (Banat, Serbia) called ‘Toutowie.’ Their ancestors came in the 19th century from Wisła (Silesian Cieszyn, Poland); they left their homes because of great hunger and were looking for jobs in Banat. Narratives about the past contain traumatic experiences of the past generations transmitted in the Silesian dialect and constituting communicative memory. At the same time, a new Polish national identity is being constructed, supported by institutions and authorities; it carries a new image of the world and creates a new cultural memory. This new identity – shaped on the basis of national categories – leads to changes of its self-identification and gives the opportunity to raise its social position in the multi-ethnic Banat community.
Urynkowione znaki pamięci
Authors: Doległo Sławomir
Published: July 2020

Commodified Memory Emblems. Historical Culture in the (Post)Consumptional Culture

Postmodernist consumption, developed by the order of self-realisation, increasingly shapes current historical awareness. Consequently, contemporary collective memory is composed not of dates and historical facts but of visual identification, slogans and varied communicative practices, so the components of popular brands which stimulate people’s consumable attitudes. The symbols of the Polish Resistance Movement during World War II as well as national colours and emblem move from historical and commemorative sphere to the sphere of pop culture. They commonly appear on T-shirts, tattoos, murals, social media profiles and political banners and are used to clarify the present day through the prism of the past, to articulate people’s ideas, concerns and affinities. The ‘language’ of memory boom surprisingly corresponds to the rhetoric of present global cultural industry, which is the ‘natural environment’ of communication for Millennials and Post-Millennials. The article is an attempt to summarise the most influential academic perspectives of current memory culture, dominated by media and consumable practices.
No labirinto de Lemnos: tragédia grega e ficção científica em The Man in the Maze de Robert Silverberg
Authors: Dagios Mateus
Published: July 2020

O texto discute a novela The Man in The Maze de Robert Silverberg (1969) e sua relação com a tragédia grega Filoctetes de Sófocles (409 a.C.), destacando a semelhança entre os enredos com destaque ao simbolismo do Labirinto no texto de Silverberg. Na relação entre tragédia grega e ficção cientifica, é explorada a recepção da antiguidade e a proeminência do New Wave como projeto de renovação do gênero de ficção cientifica a partir de novas narrativas que atendessem à demanda de um novo imaginário reivindicado pelas revoluções culturais do conturbado contexto da década de 1960.
Redes de sociabilidade, autocultuação e tradições: as práticas intelectuais do Instituto Histórico e Geográfico Brasileiro (1964-1985)
Authors: Mendes Fernanda Coelho
Published: July 2020

Como instituição intelectual, o IHGB conta ao longo de sua história já quase bicentenária com muitos rituais, tradições e redes de sociabilidade que alimentam o seu ano social e produzem material para a publicação de sua Revista. Utilizando como recorte temporal à vigência da ditadura civil-militar no país, de 1964 a 1985, este artigo se propõe a analisar as práticas intelectuais do Instituto durante este período, os rituais e tradições que compunham sua rotina, a interação entre os sócios e a interseção com outras instituições intelectuais, identificando um ponto em comum entre todas essas práticas: o culto de si. Para isso, serão utilizados como fontes os discursos, artigos, relatórios e demais documentos publicados na Revista do IHGB durante este período.
Theodoro Sampaio, Friedrich Ratzel e os Sertões de Euclides da Cunha
Authors: Sousa Ricardo Alexandre Santos
Published: July 2020

O presente trabalho trata da percepção dos sertões como possível espaço fundador da nacionalidade sob a ótica de dois intelectuais contemporâneos e que em suas interlocuções pensaram o caráter do sertanejo e a sua interação com o meio. A leitura dos sertões e dos sertanejos foi marcada naquela geração por um evento crítico, a Guerra de Canudos, que trouxe a figura do sertanejo e do sertão nordestino para o primeiro plano nas discussões acerca do caráter nacional. Em ambos os autores há subsumida a perspectiva de Friedrich Ratzel, em que o ser humano estaria intimamente ligado ao meio em que habita e disso deriva a sua possibilidade de progresso. Há, contudo nuances que diferenciam os intelectuais, Theodoro Sampaio mostrava-se menos fatalista do que o seu sucessor, Euclides da Cunha.
A importância política do Rio de Janeiro e de Buenos Aires a partir de 1808, no processo de independência do Brasil e da Argentina: questões gerais
Authors: Oliveira Hilton Meliande de
Published: July 2020

O presente artigo é uma reflexão de parte da minha tese de doutorado e pretende abordar, de forma sucinta, a importância da província do Rio de Janeiro e do Cabildo de Buenos Aires para o processo de emancipação política do Brasil e Argentina, a partir do ano de 1808, fundamental para as transformações políticas na Iberoamérica. Nesse estudo, buscou-se traçar proximidades comparativas que destaquem como as referidas sociedades optaram e levaram a diferentes concepções políticas para seus processos de independência, monarquia e república, mas que ao fim, legitimaram a manutenção de suas respectivas elites sócio-políticas previamente existentes. O uso das fontes para o caso de Buenos Aires foi estabelecido a partir de trabalhos biográficos e manuais, sua discussão, interpretação e análise se segue a partir da reflexão e estudo sobre o tema em consonância a suas perspectivas iniciais.
Horacio Ciafardini, una vida entre la ciencia y la revolución. Sistematización de su trayectoria política e intelectual (1942-1984)
Authors: Matias J. Rubio
Published: July 2020

En este trabajo sistematizamos los avances alcanzados en una investigación en curso que pretende abordar la trayectoria política e intelectual del economista argentino Horacio Ciafardini (1942-1984). Al tratarse de un trabajo en desarrollo y ante la ausencia de escritos que sistematicen esta información, en nuestra reconstrucción ponemos énfasis en los aspectos formales de su vida y no en el análisis de su producción intelectual.
Antologia de textos em português que se falam
Authors: Aires Tiago Martins
Published: July 2020

Resenha de uma publicação do Centro de Estudos Comparatistas (FLUL), uma antologia, com organização científica e universitária, que pretende oferecer um conjunto significativo de textos literários escritos dos diferentes países em que o português é a língua oficial. Esta resenha centra-se nos critérios, autores e relevância da antologia agora apresentada.
O primeiro Ivo Bender: ressonâncias do teatro épico nos primórdios do processo criativo
Authors: Da Silva Mariana Soletti
Published: July 2020

O presente trabalho busca inquirir sobre as características cruciais do teatro épico na primeira produção publicada do dramaturgo gaúcho Ivo Bender, nos anos 1960, chamada "As cartas marcadas ou Os assassinos". Examinando conceitos a fim de fundamentar em profundidade o artigo, da teoria clássica dos gêneros às particularidades do Teatro do Absurdo, refletir-se-á acerca das similitudes entre o enredo e a estrutura do texto de Bender e os atributos encontrados nas obras de Rosenfeld (1965) e Esslin (1968).
Entre os significados internos e externos: a totalidade oculta da vida e a experiência literária
Authors: Moury Fernandes Bioni Amanda
Published: July 2020

O presente artigo objetiva realizar uma breve análise sobre a convencionalidade, relativa à empreitada literária, em funcionar como um objeto de conhecimento da condição humana, especialmente, no contexto contemporâneo. Dessa maneira, a relação entre o interno e o externo é discutida, tendo em vista os gêneros literários modernos, como o romance e o poema em prosa, observando suas capacidades de representação das circunstâncias humanas, à proporção que sinaliza, assim, uma relação de causa e de consequência entre a expressão particular (localizada) e os significados universais.
Os processos de circulação do Caso Pablo Katchadjian
Authors: Amâncio Nair Renata
Published: July 2020

Apresentaremos o conceito de Objetos Derivados e a sua pertinência para pensar os processos de circulação do livro El Aleph Engordado (2009). O conceito é fruto da pesquisa A rasura da autoria na literatura contemporânea: O caso Pablo Katchadjian (Processo FAPESP: nº2017/25218-0) na qual construímos uma proposta de leitura para os objetos (#Yoborges, Reality Avoider e Apoyo a Pablo Katchadjian) que surgiram por consequência da publicação do livro El Alpeh Engordado (2009) que fez uso do conto El Aleph (1949) do celebre Jorge Luís Borges (1986). Discutiremos o Caso Pablo Katchadjian dando ênfase em seus objetos derivados e colocando em questão novas possibilidades de compreensão para a autoria no tempo presente.
O aluno experimental de poesia: um estudo sobre os diálogos presentes entre Grupo escolar de Cacaso e Primeiro caderno do aluno de poesia Oswald de Andrade de Oswald de Andrade
Authors: Dos Santos Maria Fernanda , Borba Maria Salete
Published: July 2020

Oswald de Andrade em seu livro Primeiro Caderno do Aluno de Poesia Oswald de Andrade, lançado pela primeira vez em 1927 e reeditado, em versão fac-símile, no ano de 2018, inova por sua estética experimental, em que se projeta um eu-lírico aprendiz, ou nos termos de Raúl Antelo (2006) em “Quadro e Caderno”, menino experimental. A partir da leitura do Primeiro Caderno... de Oswald de Andrade, nota-se que Cacaso faz uma releitura desse aluno experimental em sua obra poética, e esse diálogo torna-se perceptível principalmente no livro Grupo Escolar, presente na antologia LERO-LERO (2002), no qual o poeta atualiza-o posto que o insere no cenário da ditadura militar, em que a sensibilidade fora comedida e, portanto, é necessário a anarquia desse aluno experimental, que provoca o artista, por meio da sensibilidade, a ver com os olhos livres os acontecimentos cotidianos que circunscrevem sua realidade cultural, e assim, valorizá-los poeticamente.
O fluxo formulativo do texto falado dos vlogs: descontinuidade e fragmentação
Authors: Aquino Anderson Rangel Freitas de , Alomba Ribeiro Maria D'Ajuda
Published: July 2020

Os vlogs são produções textuais híbridas que se materializam sobretudo através da modalidade falada da língua. Nesse sentido, é necessário que os textos atendam não apenas às contingências do momento de sua elaboração, mas também às demandas do Youtube. Por conta disso, as falas não são totalmente espontâneas, mas costumam passar por um processo de edição que evidencia como o texto falado pode desenrolar-se de modo descontínuo. Assim, objetivamos refletir acerca do modo de construção textual dos vlogs, sobretudo quanto ao fluxo formulativo. Para tanto, utilizaremos sobretudo as contribuições de Barros (2000), Marcuschi (2005, 2008), Urbano (1998), Comolli (2007) e Cruz (2010). Para o corpus, selecionamos o canal de Francine Ehlke em virtude do formato dos vídeos e quantidade de inscritos. Evidenciamos que as descontinuidades presentes no texto falado dos vlogs atribuem ao texto maior expressividade e dinamicidade, sendo utilizadas como estratégias para a construção de sentido desse gênero.
Ressignificação narrativa dos quadrinhos para o cinema: um estudo de caso em Scott Pilgrim
Authors: Corrêa de Oliveira João Vicente , Avila Neto de Farias Ariane , Pereira Rocha Mariane , Martins Pereira Ânderson
Published: July 2020

Este estudo analisa a adaptação cinematográfica Scott Pilgrim vs O mundo (2010) de Edgar Wrigth, baseada no romance gráfico Scott Pilgrim escrito por Bryan Lee O’Maley entre 2004 e 2010. Objetiva-se investigar o processo de transposição de uma mídia para a outra, percebendo as especificidades que cada meio impõe à narrativa. A partir de um estudo comparado, analisa-se o diálogo entre as duas obras e aponta-se algumas tendências na transposição do gênero história em quadrinhos para o audiovisual. Além disso, discute-se questões referentes à adaptação e às narrativas sequenciais, estabelecendo um diálogo teórico entre elas.
My Chief Interest Is Germination: an Interview with Elisa Kay Sparks
Authors: Sparks Elisa Kay , Santos Brigida Marcela , Sant’Ana Ferreira Mendes Thales
Published: July 2020

Elisa Kay Sparks, Professor Emerita of English at Clemson University, has established a career that is a source of inspiration to any scholar in the Humanities. Having taught Literature and Women’s Studies for 35 years at Clemson, she is part of the history of entire generations of students. Furthermore, Professor Sparks's research interests and practices put her at an ideal standpoint to discuss the “connections and innovations” element of this number's theme. She is an international reference in Virginia Woolf and Modernist Studies and one of the Virginia Woolf International Society’s main collaborators. Throughout the years, she has established an impressive body of critical work investigating parks, gardens, and flowers in Woolf’s life and writing. She has also drawn innovative connections between the works of the modernist writer and those of the American painter Georgia O’Keeffe.  Taking in the stature of Professor Sparks’s contributions to Woolf Studies specifically and to the Humanities in a broader sense allows us to fully appreciate the reach of her views on the importance of sharing knowledge. For, beyond the fact that Professor Sparks is a prolific researcher, she is a truly generous one. Throughout the years, she has authored numerous blogs sharing her findings with readers and researchers entirely for free. In this interview, it becomes clear that, allied with the rigour of her academic production and her extraordinary career as a teacher, this impulse towards making knowledge and critical thinking as widely available as possible makes Professor Sparks a model of academic practice we should all aspire to.
O ensino de literatura para além da velha roupagem: entrevista com o professor Nabil Araújo
Authors: Araújo Nabil , Ribeiro Nunes Gabriela , Santos Brigida Marcela , Wallace Rodrigues dos Santos Lopes Thiago
Published: July 2020

Nabil Araújo de Souza é graduado em Letras, mestre e doutor em Estudos Literários pela Universidade Federal de Minas Gerais (UFMG). Sua tese de doutorado, intitulada “O evento comparatista: na história da crítica/no ensino de literatura”, recebeu o Prêmio UFMG de Teses, em 2014, e o Prêmio ANPOLL de Teses, em 2016. Desde 2013, atua como professor de Teoria da Literatura na graduação e na pós-graduação em Letras da Universidade do Estado do Rio de Janeiro (UERJ). Já em seu primeiro ano como professor no Instituto de Letras da UERJ, desenvolveu, junto aos seus alunos, o projeto "Ensino de literatura e desenvolvimento da competência crítica: uma 'terceira via' didático-pedagógica", que foi premiado pela Fundação Carlos Chagas como a melhor experiência educativa inovadora realizada por docente de Licenciatura em 2014. Por duas vezes, em 2015 e em 2019, foi contemplado com o Prêmio Docência Dedicada ao Ensino Anísio Teixeira, conferido pela Sub-Reitoria de Graduação da UERJ. Além disso, foi Vice-Diretor, Coordenador de Graduação e Coordenador de Licenciaturas do Instituto de Letras da UERJ.Nabil Araújo, em entrevista concedida via e-mail, discute o ensino de literatura no Brasil, abordando questões fundamentais sobre a disciplina.
Apresentação
Authors: Ribeiro Nunes Gabriela , Santos Brigida Marcela
Published: July 2020

Apresentação da edição 32.
Salud laboral desde los servicios de la administración sanitaria: las oportunidades de la “perspectiva laboral” para el ejercicio de la salud pública
Authors: García García Ana María
Published: July 2020

La interacción entre salud pública y salud laboral desde los correspondientes servicios de la administración sanitaria sigue un abordaje que se podría formular en los siguientes términos: ¿qué puede hacer la salud pública por el mejor ejercicio la salud laboral?. Así, en salud laboral se trasladan a la atención sobre la población trabajadora conceptos y herramientas propios de la salud pública tales como los sistemas de vigilancia de enfermedades o los programas de promoción de la salud que, pese a las mutilaciones que impone “la puerta de la fábrica”, contribuyen a proteger y mejorar la salud de la población trabajadora. También se apuntan con enorme potencial (y no pocas dificultades) propuestas más recientes para prevenir y actuar sobre la violencia de género desde el medio laboral o para incorporar el principio de “salud en todas las políticas” en las decisiones organizativas de la empresa. Ese espejo de las prioridades y focos de la salud pública en el ejercicio de la salud laboral ha enriquecido y seguirá enriqueciendo a esta última, aportando estrategias y nuevas oportunidades para la acción. Pero en este Editorial planteamos una perspectiva complementaria y creemos que escasamente explorada en nuestro ámbito (tampoco muy presente en la bibliografía internacional) y que respondería al siguiente planteamiento: ¿qué puede hacer la salud laboral por el mejor ejercicio de la salud pública?…
Effects of Pre-Parent Education Program Using Filial Play Therapy on the Empathy, Self-Acceptance, and Self-Efficacy of Adolescents Terminated from Protection of Institutional Care
Authors: Kim Eunjoung , Jang Mikyung
Published: July 2020

This study is to verify the effects of pre-parent education program for adolescents terminated from protection of institutional care on the empathy, self-acceptance, and self-efficacy. As the adolescents terminated from protection of institutional care are regarding their parents as the most disliked object because of feelings like distrust and hatred towards their parents while living in residential care facilities for ten years or more, the pre-parent education for them would be needed, so that they could smoothly form a family and function as a healthy parent. When the adolescents terminated from protection of institutional care become a parent, the positive parenting attitude by the increase of parent’s empathy, self-acceptance, and self-efficacy could give emotional assistance and stability to their children.
The streetwise assessment — muscle, bone and joints
Authors: Carmichael Stuart
Published: July 2020

Musculoskeletal problems are no less common in street dogs than in those living primarily indoors. It can be challenging to diagnose and manage such problems when there are only limited opportunities for investigating initial findings. Skills in history taking and physical examination are paramount. Common examples are given.
Laser-induced inner-shell excitations through direct electron re-collision versus indirect collision
Authors: Deng Yunpei , Zeng Zhinan , Komm Pavel , Zheng Yinghui , Helml Wolfram , Xie Xinhua , Filus Zoltan , Dumergue Mathieu , Flender Roland , Kurucz Máté , Haizer Ludovit , Kiss Balint , Kahaly Subhendu , Li Ruxin , Marcus Gilad
Published: July 2020

The dynamics and the decay processes of inner-shell excited atoms are of great interest in physics, chemistry, biology, and technology. The highly excited state decays very quickly through different channels, both radiative and non-radiative. It is therefore a long-standing goal to study such dynamics directly in the time domain. Using few-cycle infrared laser pulses, we investigated the excitation and ionization of inner-shell electrons through laser-induced electron re-collision with the original parent ions and measured the dependence of the emitted x-ray spectra on the intensity and ellipticity of the driving laser. These directly re-colliding electrons can be used as the initiating pump step in pump/probe experiments for studying core-hole dynamics at their natural temporal scale. In our experiment we found that the dependence of the x-ray emission spectrum on the laser intensity and polarization state varies distinctly for the two kinds of atomic systems. Relying on our data and numerical simulations, we explain this behavior by the presence of different excitation mechanisms that are contributing in different ratios to the respective overall x-ray emission yields. Direct re-collision excitation competes with indirect collisions with neighboring atoms by electrons having “drifted away” from the original parent ion.
Terahertz time-domain spectral imaging using telecentric beam steering and an f-θ scanning lens: distortion compensation and determination of resolution limits
Authors: Harris Zachery B. , Virk Arjun , Khani Mahmoud E. , Arbab M. Hassan
Published: July 2020

We report on the development and performance characterization of a telecentric terahertz spectroscopic scanner using an f-θ objective lens and a single gimballed scanning mirror for image formation. We derived a beam steering transform to compensate for the intercoupling of the gimballed mirror axes and the distortions caused by an imperfect scanning lens. We characterize the optical performance of the system in both the time and spatial domains, demonstrating a constant diffraction-limited imaging resolution over the entire field of view. Finally, given the large depth of focus of the objective lens, we demonstrate the broadband imaging capability at different depths using a Boehler star target. This imaging setup has the potential to be miniaturized into portable form factors for field-deployable scenarios.
A MEMS lens scanner based on serpentine electrothermal bimorph actuators for large axial tuning
Authors: Zhou Liang , Yu Xiaomin , Feng Philip X.-L. , Li Jianhua , Xie Huikai
Published: July 2020

Confocal microscopes and two-photon microscopes are powerful tools for early cancer diagnosis because of their high-resolution 3D imaging capability, but applying them for clinical use in internal organs is hindered by the lack of axially tunable lens modules with small size, high image quality and large tuning range. This paper reports a compact MEMS lens scanner that has the potential to overcome this limitation. The MEMS lens scanner consists of a MEMS microstage and a microlens. The MEMS microstage is based on a unique serpentine inverted-series-connected (ISC) electrothermal bimorph actuator design. The microlens is an aspheric glass lens to ensure optical quality. The MEMS microstage has been fabricated and the lens scanner has been successfully assembled. The entire lens scanner is circular with an outer diameter of 4.4 mm and a clear optical aperture of 1.8 mm. Experiments show that the tunable range reaches over 200 µm at only 10.5 V and the stiffness of the microstage is 6.2 N/m. Depth scan imaging by the MEMS lens scanner has also been demonstrated with a 2.2 µm resolution, only limited by the available resolution target.
Harmonic and rational harmonic driving of microresonator soliton frequency combs
Authors: Xu Yiqing , Lin Yi , Nielsen Alexander , Hendry Ian , Coen Stéphane , Erkintalo Miro , Ma Huilian , Murdoch Stuart G.
Published: July 2020

With demonstrated applications ranging from metrology to
telecommunications, soliton microresonator frequency combs have
emerged over the past decade as a remarkable new technology. However,
standard implementations allow only for the generation of combs whose
repetition rate is tied closely to the fundamental resonator
free-spectral range (FSR), offering little or no dynamic control over
the comb line spacing. Here we propose and experimentally demonstrate
harmonic and rational harmonic driving as novel techniques that allow
for the robust generation of soliton frequency combs with discretely
adjustable frequency spacing. By driving an integrated Kerr
microresonator with a periodic train of picosecond pulses whose
repetition rate is set close to an integer harmonic of the 3.23 GHz
cavity FSR, we deterministically generate soliton frequency combs with
frequency spacings discretely adjustable between 3.23 GHz and
19.38 GHz. More remarkably, we also demonstrate that driving the
resonator at rational fractions of the FSR allows for the generation
of combs whose frequency spacing corresponds to an integer harmonic of
the pump repetition rate. By measuring the combs’ radio-frequency
spectrum, we confirm operation in the low-noise soliton regime with no
supermode noise. The novel techniques demonstrated in our work provide
new degrees of freedom for the design of synchronously pumped soliton
frequency combs.
Common-clock very long baseline interferometry using a coherent optical fiber link
Authors: Clivati Cecilia , Aiello Roberto , Bianco Giuseppe , Bortolotti Claudio , De Natale Paolo , Di Sarno Valentina , Maddaloni Pasquale , Maccaferri Giuseppe , Mura Alberto , Negusini Monia , Levi Filippo , Perini Federico , Ricci Roberto , Roma Mauro , Santamaria Amato Luigi , Siciliani de Cumis Mario , Stagni Matteo , Tuozzi Alberto , Calonico Davide
Published: July 2020

Among the most powerful techniques for the exploration of the Universe is very long baseline interferometry (VLBI), which is based on the simultaneous observation of radio sources in the sky with arrays of distant ground-based antennas. One of the effects currently limiting its ultimate sensitivity is the phase-instability of the reference clocks adopted at each antenna. This term can be made negligible delivering the same clock signal to multiple telescope sites using optical fibers. We realized such an infrastructure by disseminating a coherent optical frequency signal to two distant radio telescopes using a 1739-km-long fiber. We performed a 24 h geodetic VLBI campaign in which the same clock reference was used at both telescopes and analyzed it using standard VLBI procedures. The results were consistent with the expectations, confirming that the proposed approach is feasible and configures as a novel tool for studying the role of clocks, troposphere, and systematic effects in the ultimate VLBI resolution.
Notas sobre la Cancillería del Onceno en tiempos de Minoridad: a propósito de dos cartas de Alfonso XI a la Orden de Santiago
Authors: López Gómez Érika
Published: July 2020

El estudio de la documentación de Alfonso XI ha sido una de nuestras principales áreas de investigación durante los últimos años. Su análisis pormenorizado nos ha permitido conocer a fondo la escritura de la primera mitad del siglo XIV, así como la actividad y funciones de la Cancillería real. Centramos nuestra atención en los diplomas depositados en la sección de Órdenes Militares del Archivo Histórico Nacional, de los cuales hemos creído conveniente revisar dos, emitidos durante el tiempo de las tutorías, por cuanto detectamos ciertos elementos susceptibles de realizar una crítica diplomática. Gracias a su examen, hemos podido establecer cuál era la práctica cancilleresca en aquel periodo cronológico y hemos comprobado que durante la menor edad del Onceno fueron frecuentes las corruptelas y mala praxis de quienes formaban parte de la principal oficina de expedición documental.
Pactos y tensiones en un espacio de pluralidad identitaria y jurisdiccional. El sudeste peninsular a inicios del siglo XV
Authors: Soler Milla Juan Leonardo , López García José Carlos
Published: July 2020

Las razzias y las agresiones entre miembros de distinta soberanía o comunidad religiosa en los espacios de frontera bajomedievales, provocaron en sus sociedades una reacción contra la misma en forma de instituciones y pactos para la persecución de los malhechores y la restitución de las víctimas. En el presente artículo se analiza la eficacia de acuerdos como la Hermandad entre cristianos y musulmanes en la Gobernación de Orihuela y la colaboración entre el Adelantamiento de Murcia y la Gobernación de Orihuela para resolver incidentes fronterizos, a partir de casos que reflejan las trabas que implicaban la multiplicidad de jurisdicciones, la connivencia con los delincuentes y la confrontación de intereses, de modo que supone una revisión de los trabajos previos referidos a este tipo de instituciones y acuerdos.
La frontera nororiental y oriental del distrito andalusí de Lleida (ss. X-XI)
Authors: Brufal i Sucarrat Jesús
Published: July 2020

La frontera nororiental y oriental del distrito andalusí de Lleida se configura a partir del siglo IX y se rompe a principios del siglo XI, prácticamente coincidiendo con la fitna de 1010. Este vasto territorio se organiza a partir de los cursos fluviales y las llanuras fértiles bien antropizadas como la correspondiente al ager de Guissona (Iesso). Estas realidades geográficas e históricas en forma de herencia territorial clásica, se vertebran desde una perspectiva andalusí, de aquí la instalación de comunidades rurales cerca de los cursos fluviales, la construcción de fortalezas como Calaf, la presencia de ribats en sus proximidades y, se garantiza la comunicación terrestre resiguiendo los valles fluviales o vías de comunicación, también, preexistentes.
La retórica de la concordia y de la tolerancia con el islam: una nueva frontera
Authors: Cruz Palma Óscar de la
Published: July 2020

La victoria de los turcos sobre Constantinopla en 1453 confirmó al enemigo sarraceno como la potencia dominante en el Mediterráneo oriental. Tras siglos de denostación del islam y de acciones bélicas y de cruzadas, ahora el occidente cristiano debía poner en marcha un sistema diplomático que permitiera mantener relaciones internacionales con el poderoso mundo islámico. En estas circunstancias, las artes (y no sólo la literatura) se volvieron a mostrar como un instrumento útil para reconstruir estas relaciones diplomáticas. La retórica basada en la idea de concordia y tolerancia se ofreció entonces como un instrumento muy eficaz; sin embargo, lejos de aproximar a los pueblos y construir una sola nación de pueblos, realmente la nueva retórica servía para construir una frontera entre enemigos que debían respetarse y mantener las distancias.
Territorio y poblamiento en la frontera nororiental granadina. La Hoya de Baza y el Altiplano
Authors: Malpica Cuello Antonio
Published: July 2020

La investigación sobre las formas materiales de vida y la organización del territorio de un espacio fronterizo, el situado en el extremo nororiental del reino nazarí de Granada, obliga a un examen de las fuentes escritas y un análisis predominantemente arqueológico. A partir de ellos, dentro de la Arqueología del Paisaje, hemos podido estudiar los asentamientos humanos, en su mayor parte fortificados, la estructuración de las actividades agrícolas y ganaderas. Hemos visto así que el distrito al norte de la ciudad de Baza tenía una gran capacidad productiva, más allá de la agricultura irrigada, y que estaba, además, integrada en su condición de tierra de frontera.
Faktor Hidro-Oseanografi Terhadap Distribusi Air Tawar Bersuhu Rendah Dekat Pantai Sekitar Lokasi Keluaran Air Tanah Lepas Pantai (KALP) di Perairan Lombok Utara, Indonesia
Authors: Wisha Ulung Jantama , Kusumah Gunardi
Published: July 2020

The Influence of Hydro-Oceanography Factors on the Distribution of Near-shore Low-Temperature Freshwater around Submarine Groundwater Discharge (SGD) Area in the North Lombok Waters, Indonesia. North Lombok coast has lot of resources of Submarine Groundwater Discharge (SGD). The biggest discharge appeared in the Krakas Beach where cold groundwater discharge many spots might trigger anomalies in the ambient water temperature. This study was aimed at determining the distribution of the cold groundwater discharge. A field survey was conducted on March 23th -26th, 2016. Flow model and statistical analysis were employed to determine the transport pattern of temperature anomalies. Vertically, the current direction is in accordance with Ekman spiral that triggers the vertical cold groundwater distribution. The current speed during the displacement toward high tide ranges 0-0.15 cm/s which predominantly moves south-westward. During low tide, tidal current was predominantly north-eastward moving at 0-0.3 cm/s. Temperature variation around the SGD spot fluctuated following sea surface surface elevation dynamics in which these two parameters has a correlation value of 63%.
Karakterisasi Enzim Xilanase dari Isolat Bacillus sp. UJ131 di Hutan Mangrove Margasari Lampung Timur sebagai Kandidat Probiotik
Authors: Sumardi Sumardi , Farisi Salman , Ekowati Christina Nugroho , Hairisah Suminta Frida
Published: July 2020

Characterization of Xilanase Enzyme by Bacillus sp. UJ131 A Probiotic Candidate from the Mangrove of Margasari, East Lampung. Mangrove are known to have high biodiversity as a potential location for exploration of enzyme-producing bacteria, one of which is the xylanase enzyme. Xylanase is an enzyme that hydrolyzes the xylan-rich hemicellulose substrate. This research aims to produce and know the character of xylanase enzyme by Bacillus sp. UJ131 isolate which was isolated from the oriental shrimp in Margasari mangrove forest of East Lampung. Xylanase enzymes are produced from the bacteria by growing them in sea water complete (SWC) broth containing xylan beechwood. Characterization xylanase enzyme consist of pH, temperature, and metal ions. The results showed that xylanase had an optimal time of 18 hours with xylanase activity of 0.18 U/ml, and optimally at pH 6 and temperature 70°C. The addition of Mn2+ and Ca2+ ions increase enzyme activity, but Fe3+, Cu2+ and Mg2+ ions decrease xylanase enzyme activity. At a maximum reaction speed of 0.25 U/ml, the xylanase enzyme can produce 1.30 μM xylose per minute
Kehadiran Gelombang Soliter dan Transpor Sesaat Sedimen tersuspensi di Perairan Pantai Bengkulu Tengah
Authors: Kusmanto Edi , Hasanudin Muhammad
Published: July 2020

Existence of Solitary Waves and Transient Suspended Sediment Transport in the Coastal Waters of Central Bengkulu. Coastal abrasion and suspended sediment transport driven by waves is occurring dreadfully in the coastal waters of Central Bengkulu. The abrasion tends to be accelerated by solitary waves during the southeast monsoon season. The primary data were obtained  on 17-26 July 2014, while the secondary data derived from Google Maps imageries obtained on 17 June 2014, representing the southeast monsoon season. The primary data were collected by 1200 KHz Acoustic Doppler Current Profiler (ADCP) for water currents, a single beam Echosounder for  depths, Garmin 276C GPS receiver for coordinate positions, RBR-TWR2050 (installed at at a fixed point at 102.2219 °E and 3.6916 °S and depth of 9 m) for height and wave periods, and a compass for the direction of wave propagation. The secondary data included Astrium satellite imageries compiled by Google Earth and displayed as Google Maps images on 17 June 2014. These images were used for identifying the appearance of wave groups and by using a feature in Google Earth, it showed that the estimated distance between wave packets hitting the coast accounted for 147 m. This study showed the existence of solitary waves with height and wave period of 1.02 m and 13.85 seconds respectively, while the wave length reached 147.7 m. The wave energy and wave energy flux were 1123.12 Jm-2 and 12018.94 Jm-1s-1, calculated by using the cnoidal wave theory and solved by the KdV equation. These solitary waves have large destructive forces on unstable cliffs along the coasts. Derived from coastal abrasion processes and shown by the ADCP backscatter intensity with the highest of 146 dB, the suspended sediments were likely to be transported by water currents with an average speed of 25.99 cm s-1 in the dominant direction to the south - southeast; and the sediments were deposited along the coast of Bengkulu City.
O biopoder no conteúdo da TV
Authors: Bertolini Jeferson
Published: July 2020

Este artigo apresenta resultados de estudo sobre a relação entre biopoder (técnica de poder que busca produzir corpos economicamente ativos) e a TV brasileira. O objetivo é mostrar que o conteúdo veiculado por programas de TV sobre saúde e bem-estar é compatível com o biopoder. Como técnica, o trabalho usa análise de conteúdo do programa Bem Estar, da Rede Globo. O manuscrito conclui que o conteúdo veiculado pelo programa é compatível com o biopoder porque incide majoritariamente sobre o corpo, o mesmo alvo do biopoder, com o pretexto de preservá-lo ou torná-lo saudável.
Identification and quantification of Cyanotoxins in Lake and household water around Lake Victoria, Kenya
Authors: Otoigo Lilian
Published: July 2020

Cyanobacteria are single-celled algae that thrive in warm and nutrient rich water bodies. They can produce different kinds of toxins called cyanotoxins that can affect the liver. Cyanobacteria have been reported in Lake Victoria, which is an important source of drinking water for the riparian communities. This is as a result of eutrophication in Lake Victoria increasing the levels of cyanobacteria in the Nyanza Gulf. The purpose of this study was to identify and quantify microcystins in household and Lake Victoria water in Nyanza Gulf. In a longitudinal study adopting experimental design, six beaches were studied and 127 samples collected monthly from both households and beaches over six months. Cyanobacterial levels were determined using an enzyme assay method (PP2A) and microcystin strains identified using High Performance Liquid Chromatography (HPLC). Two-way ANOVA was done to determine statistical significance of microcystins. The results showed that all beaches were eutrophic resulting in flourishing of cyanobacteria. 84% of water samples contained microcystins. Concentration of microcystins was 3.44g/L. Microcystin RR (MC-RR) is the most abundant cyanotoxins followed by Microcystin YR (MC-YR) and Microcystin LR (MC-LR) is the least abundant in the Nyanza Gulf. There was significant variation between different beaches and different months (ANOVA: F=12.09, p<0.0005). This information provides an insight into the quality of Lake Victoria water for drinking based on quantities of microcystins in the sampled water. The study recommends regular monitoring of cyanobacterial cells in the lake water.
OPTIMIZATION OF A SMALL SOLAR CHIMNEY
Authors: Castro Silva Janaina Oliveira , Maia Cristiana Brasil
Published: July 2020

An optimization study to maximize the exergy efficiency of a small-scale solar chimney was carried out. Optimization variables include collector diameter (Dc), collector height (Hc), tower height (Ht), and tower diameter (Dt). Models from the literature were used to predict environmental and airflow parameters. Exergy efficiency and solar chimney efficiency were determined, on an hourly basis, for a one-year period. The model was simulated using the EES software. Two methods of optimization were used, the method of conjugate directions and the method of variable metric, both providing similar results. Results were compared to the results from an experimental prototype, and it was found that the energetic and exergetic efficiency were significantly improved. The analysis indicated that the height and diameter of the chimney and collector are the most important physical variables in the design of a solar chimney. For both methods, it was found that the maximum exergy efficiency was obtained with a collector height of 0.5 m, a collector diameter of 30 m, a tower diameter of 1 m, and a tower height of 17.8 – 18.8 m. The exergy efficiency was 44 %.
ASPECTOS HIDROGEOMORFOLOGICOS E A DISTRIBUIÇÃO ESPACIAL DA HANSENÍASE EM GUARAPUAVA – PR
Authors: Geffer Edivaldo , Díaz Christian Junior Licheski
Published: July 2020

A geografia da saúde busca contribuir com uma medicina preventiva, evidenciando os aspectos geográficos que contribuem para o desenvolvimento e incidência das doenças. Neste sentido foi feito um estudos sobre Hanseníase, analisando geograficamente a partir das concepções da geografia da saúde e de fatores Hidrogeomorfológicos na área urbana da cidade de Guarapuava-PR. Para tal, foram utilizados ferramentas do Sistema de Informação Geográfica (SIGs), para qualificação, distribuição, mapeamento e elaboração de gráficos a respeito do desenvolvimento dos focos destes agravos, os dados foram disponibilizados pelo Ambulatório Municipal de Pneumologia e Dermatologia Sanitária (AMPDS). Foi investigado a existência ou não de relação entre fatores hidrogeomorfológicos e a distribuição espacial de 304 casos confirmados de hanseníase residentes na área urbana da cidade de Guarapuava, entre 2001 a 2013. Trabalhos in loco foram desenvolvidos para analisar as possíveis fontes de contaminação, verificando pessoalmente os prováveis fatores que influenciam o aparecimento e o desenvolvimento destas doenças. Dentre os resultados obtidos destaca-se que as áreas com concentração de casos de Hanseníase em Guarapuava são regiões periféricas, carentes de infraestrutura básica de saneamento. Tendo a faixa etária da população mais atingida, a população economicamente ativa. Constatou-se ainda que muitas das residências com casos registrados observadas apresentam solo exposto e proximidade a corpos de água. A espacialização dos casos de Hanseníase torna-se uma ferramenta fundamental uma vez que, possibilita ações por parte do poder público em locais estratégicos do espaço urbano com maior concentração de casos.
Covid-19 em revistas no Instagram: uma análise de conteúdo relacionada às orientações do UNICEF e da OMS
Authors: Leão Callenciane Ferreira , Serafim Luciana Santos , Nunes Dháfine Mazza , Pereira Germana da Cruz
Published: July 2020

No presente artigo analisamos como as revistas brasileiras Crescer e Pais & Filhos, cuja temática principal é família, abordam em seus perfis na rede social Instagram a pandemia Covid-19 no período de 12 de março a 11 de abril de 2020. Para tanto, tomamos como base teórica as discussões sobre comunicação e teoria do agendamento de Maxwell McCombs e DonaldShaw (1970) e redes sociais de Castells (2002) e Recuero (2009). Com isso, identificamos temas abordados com recorrência no período analisado, categorizando as postagens conforme os assuntos e analisando seu alinhamento com as orientações do UNICEF e OMS sobre Covid-19, família e crianças durante o isolamento social. Ao final, observamos o agendamento da pandemia nas publicações dos perfis, bem como uma aproximação às diretrizes dos órgãos internacionais.