bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Continuous Nursing Intervention on Exercise Tolerance and Rehospitalization Rate in Patients with Chronic Heart Failure
Authors: Sun Xiao-li , Shi Zhao-yun , Wang Na
Published: December 2021

To observe the effect of continuous nursing intervention on exercise tolerance and rehospitalization rate in patients with chronic heart failure. Methods 134 patients with chronic heart failure admitted to our hospital were divided into two groups, routine nursing intervention group
(control group) and continuous nursing intervention group (observation group), with 67 cases in each group. The resting and peak heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) of the two groups were recorded. The change of 6min walking distance, modified
European Heart Failure Self-Care Behavior Scale (EHFSCB-9) and quality of life (SF-36) of the two groups were compared before and after intervention, and moreover, rehospitalization rate of heart failure of two groups 6 months after discharge was compared between the two groups. Results :
Before intervention, there was no significant difference between the two groups (P>0.05). After intervention, there was no significant difference in resting and peak HR, SBP and DBP between the two groups and those before intervention (P>0.05). Further comparison between the two groups
showed that there was no significant difference in resting and peak HR, SBP and DBP between the observation group and the control group (P>0.05). After intervention, 6min walking distance and SF-36 scale scores (role physical, physiological function, physical pain, energy, health status,
social function, mental health and emotional function) were increased in the two groups (P<0.05). Further comparison between the two groups showed that 6min walking distance and SF-36 scale scores (except somatic pain score and role physical score) in the observation group were higher than
those in the control group (P<0.05), and the EHFSCB-9 scores in the two groups decreased gradually after intervention (P<0.05). Further comparison between the two groups showed that the EHFSCB-9 scores in the observation group (except low salt diet score and taking medicine based on
doctor’s advice score) were lower than those in the control group (P<0.05). The rehospitalization rate of heart failure within 6 months after discharge was 11.91% in the observation group, significantly lower than 25.37% in the control group, and the difference was significant (P<0.05).
Conclusion : Continuous nursing intervention can strengthen the self-care ability of patients with chronic heart failure, improve exercise tolerance and quality of life, and reduce the rehospitalization rate to heart failure within 6 months.
Effect of Rapid Rehabilitation Concepts on Quality of Life and Pain in Patients Undergoing Radical Breast Cancer Surgery in Perioperative Period
Authors: Li Xin , An Hai-yan , Zhao Yi , Ji Mingli , An Jing , Tao Yan
Published: December 2021

To study the effect of rapid rehabilitation nursing on patients’ quality of life and pain level during the perioperative period of radical breast cancer surgery. Methods: 126 patients who were hospitalized in our hospital from January 2018 to February 2020 and underwent radical
breast cancer surgery were divided into control group and rapid rehabilitation group according to the perioperative period intervention method. Routine nursing intervention and rapid rehabilitation nursing intervention were used respectively. The general conditions of the two groups were recorded,
and the differences of T cell subsets before operation and 3 days after operation were detected. Visual analogue pain (VAS) score was used to evaluate the changes of pain degree at 1 day, 3 days and 5 days after operation and on the day of discharge. Postoperative complications and satisfaction
were compared between the two groups. Quality of life (QOL) was assessed at 1 month and 3 months after operation using the CARES-SF score. Results: Anesthesia waking time (26.12 ± 5.77) min, off-bed activity time (14.25 ± 2.87) h and hospital stay (7.82 ± 2.15) d in the
rapid rehabilitation group were shorter than those in the control group (P < 0.05). The operation time (92.02 ± 14.78) min and intraoperative blood loss (57.96 ± 13.96) mL in the rapid rehabilitation group were not significantly different from those in the control group (P
> 0.05). In the control group, 3d after operation, T lymphocyte subsets were decreased gradually than that before operation (P < 0.05), CD3+ was decreased 3d after operation than that before operation in the rapid rehabilitation group (P < 0.05), but CD4+, CD8+, CD4+ / CD8 + 3d after
operation had no significant difference than that before operation (P > 0.05). In rapid rehabilitation group, T lymphocyte subsets at 3d after operation were higher than those in the control group (P < 0.05). The postoperative complication rate of the rapid rehabilitation group was lower
than that of the control group, and the satisfaction degree was higher than that of the control group, with significant difference (P < 0.05). After follow-up, it was found that the scores of qualities of life, such as physiology, psychosocial, marriage, sexual life and relationship with
medical staff in the rapid rehabilitation group were lower than those in the control group at 1 month and 3 months after operation (P < 0.05). Conclusion: The concept of rapid rehabilitation nursing can stabilize the immune function of patients after radical breast cancer surgery, promote
the postoperative rehabilitation and improve the quality of life after operation.
Study on Effectiveness Analysis of Multi-Media Combined with PBL Teaching in Breast Surgery
Authors: Zhang Xusheng , Guo Yiqing , Wang Ji , Zhang Xudong , Cheng Junsheng , Chen Haoqiang , Pi Qixing
Published: December 2021

To explore the effectiveness of multi-media combined with PBL teaching in breast surgery. Methods: 56 interns who came to our hospital for breast surgery from January 2019 to December 2020 were randomly divided into two groups: traditional teaching control group (n = 28) and multi-media
PBL teaching observation group (n = 28). Two groups’ theoretical knowledge, skill operation, teaching quality, student’s evaluation and satisfaction with the teaching model were compared before ending the internship. Results: The total scores of breast examination, differential
diagnosis, imaging reading, diagnosis and treatment scheme and total scores of the students in the observation group were higher than those of the students in the control group, and the total scores of body position, surgical site selection, disinfection and local anesthesia, surgical operation,
postoperative treatment and clinical operation skills were also higher than those of the students in the control group (P < 0.05), but there was no significant difference between the two groups in medical history collection, professional knowledge and preoperative preparation (P > 0.05).
The teaching quality of the students in the observation group was also significantly higher than that in the control group (P < 0.05). In addition, the students’ satisfaction with the teaching method, the teaching effect and the overall satisfaction in the observation group were significantly
higher than those in the control group (P < 0.05). Conclusion: Multi-media combined with PBL teaching can effectively improve students’ professional knowledge theory level, operation skills, enhance students’ enthusiasm and initiative, develop good clinical thinking habits,
and have high teaching satisfaction. It is worthy of being popularized in the clinical teaching of breast surgery.
Analysis of the Effect of Advanced Nursing on the Quality of Life and the Prevention of Complications in Patients with Breast Cancer Undergoing PICC Chemotherapy
Authors: Hu Xiuzhen , Yang Qun , Wang Zhengyun , Hu Xuyun
Published: December 2021

Objective: To investigate the effect of advanced nursing on the quality of life and the prevention of complications in patients with breast cancer undergoing PICC (Peripherally Inserted Central Catheter) chemotherapy. Methods: From January 2017 to January 2020, 98 patients with breast
cancer undergoing PICC chemotherapy in our hospital were divided into control group and study group by random sampling. The patients were given routine nursing and advanced nursing intervention on the basis of routine nursing. The psychological status, complications and quality of life of
the patients were compared. Results: There was no significant difference in HAMA, HAMD score and QLQ-30 score before nursing (P > 0.05). The scores of HAMA and HAMD in the study group after nursing were lower than those in the control group (P < 0.05), the scores of QLQ-30 were higher
than those in the control group (P < 0.05), and the complication rate was lower than that in the control group (P < 0.05). Conclusion: The intervention of advanced nursing mode in patients with breast cancer treated with PICC chemotherapy can effectively alleviate the influence of negative
emotion on chemotherapy, reduce the occurrence of complications and improve the quality of life. This mode has high clinical value.
Angelica Sinensis Polysaccharide Mediates Sirtl to Inhibit P53/P21 Pathway and Delay Hematopoietic Stem Cell Aging
Authors: Li Hong-hui , Wang Qian-xing , Du You-hong , Tang Shi-huan , Peng Lu , Long Ting , Zhang Hui , Zhang Hong-mei , Wang Ya-ping , Wang Xuan-ya , Liao Ting , He Yu-lan , Xie Wei-wei , Zhang Xian-ping
Published: December 2021

To study the effect of Angelica sinensis polysaccharide (ASP) on the expression of Sirt1/p53/p21 in radiation-induced aging hematopoietic stem cells (HSCs) of mice, and to explore the possible mechanism of ASP regulating the aging of HSCs. Methods: C57BL/6J mice were randomly divided
into control group, model group and ASP group. The model group was irradiated with X-ray 3.0Gy/8F to establish the aging model of HSCs in mice. ASP group was given ASP intragastric administration during irradiation; The control group and the model group were given equal volume of normal saline.
HSCs were sorted by immunomagnetic beads, and cell cycle was detected by flow cytometry The aging cells were observed by α-galactosidase staining. The directional differentiation ability of HSCs was observed by mixed colony culture (CFU-Mix). The expression of Sirtl, p53 and p21 protein
was detected by Western blot. Results: Compared with the control group. X-ray can significantly increase the proportion of HSCs Gi cells, the rate of SA-α-Gal positive cells and the expression of p53 and p21 protein in aging group (P<0.05).The expression of Sirtl and mixed colony
forming ability were decreased (P<0.05). Compared with the model group, ASP inhibited the increase of aging HSCs Gicell ratio, SA-fJ-Gal positive cell rate and p53 and p21 protein expression (P<0.05). At the same time, Sirtl expression and mixed colony forming ability were
increased (P<0.05). conclusion: ASP may inhibit p53/p21 pathway and delay the aging of mouse HSCs by regulating Sirtl.
Protective Effects of Butylphthalide on Cerebral Infarction Induced by Local Ischemic Injury and Regulation Mechanism of the Pi3k/Akt/Gsk-3β Signaling Pathway
Authors: Liu Chong , Cao Yan
Published: December 2021

Aim: We aimed to study the protective effects of butylphthalide (NBP) on cerebral infarction induced by local ischemic injury and regulation mechanism of the PI3K/Akt/GSK-3β signaling pathway. Materials and methods: One hundred male Wistar rats aged 12-15 weeks were randomly
divided into 5 groups (n=20). The middle cerebral artery occlusion (MCAO) model was established. NBP, P13K specific inhibitor LY294002 and NBP plus LY294002 groups were intraperitoneally administered on the first day after modeling, once a day for 7 days. Sham operation (Sham) and model groups
were intraperitoneally given equal amounts of normal saline. Modified neurological severity (mNS) was scored 30 min after administration on the 7th day, and cerebral infarction volume was measured by magnetic resonance imaging. Neuronal damage was detected by Nissl staining. Intact neurons
were counted under light microscope. The protein expressions of Akt, P-Akt, GSK-3β and P-GSK-3β were detected by Western blotting. Results:The mNS score of NBP group decreased significantly compared with that of model group (P<0.05). Compared with model group, the cerebral
infarction volume of NBP group significantly reduced (P<0.05). Compared with model group, the number of intact neurons in NBP group significantly increased (P<0.05). Compared with model group, the phosphorylation levels of Akt and GSK-3β in NBP group significantly increased (P<0.05).
Conclusions: By activating the PI3K/Akt/GSK-3β signaling pathway, NBP relieves neurological function damage and protects against cerebral infarction induced by local ischemic injury.
Analysis of the Protective Effect of Interleukin-5 On Sepsis Mice
Authors: Wang Xiaokun , Pei Fuyang , Song Xiaoping , Wang Hongmei
Published: December 2021

IL-5 can stimulate the growth and differentiation of EOS, inhibit its apoptosis and stimulate the proliferation and differentiation of B cells with other cytokines, and act on mature B cells to promote the synthesis of IgA and IgM. Therefore, this paper takes C57BL / 6 mice as the
experimental object to explore the protective effect of interleukin-5 on sepsis mice. The experimental results show that the serum cxcl-1 in sepsis model group is significantly higher than that in control group at each time point, reaching the peak at 12 h, while cxcl-1 in IL-5 intervention
group is significantly lower than that in control group. IL-5 can reverse the liver injury induced by CLP in septic mice, the mechanism may be to reduce the production of inflammatory factors in the liver, and the liver function of mice was not damaged 12 hours after sepsis. IL-4 and IL-13
of type 2 inflammatory response factors can promote the conversion of macrophages to anti-inflammatory macrophages, inhibit the inflammatory reaction, and play a protective role in sepsis.
Red Blood Cell Distribution Width in Holistic Nursing Mode for Patients with Acute Left Heart Failure
Authors: Wang Jing , Cui Xusheng , Gong Xiaodan , Zhai Yun , Zhang Yunqing , Yao Shuang , Kong Xiaomei
Published: December 2021

Acute left heart failure is a very common acute heart failure in clinic, which must be treated immediately. If the treatment time is delayed, the mortality will be greatly increased. At present, there is not a good index to judge the severity of acute left heart failure. Therefore,
it is necessary to analyze the relevant data and find a suitable measurement index. The purpose of this paper is to study the application effect of red blood cell (RBC) distribution width in holistic nursing mode for patients with acute left heart failure, taking patients with acute left heart
failure in our hospital as the research object. The RBC distribution width of patients was detected, and the mortality and symptom relief time of patients were counted. The results showed that there was no significant difference in mortality when RBC distribution width was young. When the
RBC distribution width is greater than 14.6%, the mortality rate increases rapidly. The symptom relief time of holistic nursing group was much shorter than that of general duty nursing group, and the difference was the biggest when it was over 14.6% in RBC distribution width, reaching 8.5
minutes. In the holistic nursing group, there was no significant difference in symptom relief time. In the group of general duty nursing, when the RBC distribution width is more than 14.6%, the time of symptom relief increases sharply. RBC distribution width can be considered to predict the
severity of a patient’s lines.
Analysis of Clinical Effect of Arthroscopic Minimally Invasive Surgery on Patients with Knee Joint Bone Trauma
Authors: Chen Ligang , Lin Hao
Published: December 2021

To study and analyze the clinical effect of arthroscopic minimally invasive surgery in the treatment of knee joint trauma. Methods: A total of 80 patients with knee joint bone trauma who were treated in our hospital from July 2018 to July 2019 were selected as the research objects,
and randomly divided into observation group and control group. Patients in the control group were treated in the conventional way, patients in the observation group were treated with arthroscopic minimally invasive surgery, and the treatment effect, neer score and complications of the two
groups were compared. Result: The treatment efficiency of the observation group was significantly higher than that of the control group (P < 0.05); the neer score of the observation group was significantly higher than that of the control group (P < 0.05); the number of complications
in the observation group was significantly lower than that of the control group (P < 0.05), the difference was statistically significant. Conclusion: The application of arthroscopic minimally invasive surgery in the treatment of knee joint trauma patients has significant effect, improve
the treatment effect, the number of patients with complications is lower, with higher safety, which is worth promoting in clinical treatment.
NEW RECORDS OF THREE SPECIES OF TREEFROGS (RHACOPHORIDAE: AMPHIBIA) FROM NORTHEASTERN VIETNAM
Authors: Nguyen Van Thinh , Nguyen Thien Tao , Luong Mai Anh , Pham The Cuong , Nguyen Quang Truong
Published: December 2021

We herein report three new provincial records of the family Rhacophoridae from northeastern Vietnam: Rhacophorus orlovi from Ha Giang province, and Theloderma rhododiscus and Zhangixalus puerensis from Cao Bang province. Additional morphological data and natural history of the aforementioned species are also provided based on newly collected specimens.
ANALYSIS OF GENETIC DIVERSITY OF 26 CASSAVA VARIETIES (Manihot esculenta CRANTZ) WITH DIFFERENT RESPONSES TO WATERLOGGING CONDITIONS BY USING RAPD MARKERS
Authors: Dethvongsa Sengsoulichan , Nguyen Anh Vu , Tran Khanh Van
Published: December 2021

RAPD (Randomly Amplified Polymorphic DNA) is an indicator for high and stable polymorphism, widely used in the study of the diversity of cassava. In this paper, the results of using 20 polymorphic primers OPK combined with the establishment of the phylogenetic tree to analyze the genetic diversity of 26 cassava varieties with different responses to waterlogging conditions by using the RAPD-PCR technique were presented. The purpose of this experiment was to show the genetic relevance of the studied cassava varieties. The results showed that the flood tolerance of cassava was not related to the polymorphism and branching characteristics of the stem. This information may be use as a basis for selecting flood-tolerant cassava varieties for cassava production, as well as the basis for selecting genetically different parents for breeding.
ESTIMATION OF LAND SUBSIDENCE IN THE MEKONG DELTA AND ITS SURROUNDING AREAS
Authors: Dang Vu Khac , Phan Trong Trinh , Dinh Xuan Vinh
Published: December 2021

Land subsidence becomes a trouble for the different regions of the Mekong delta, where many places will be severely affected by sea-level rise in the context of climate change. Land subsidence could amplify this situation by inducing interactive hazards such as submerged land and saline intrusion, etc. Mapping the spatial distribution of land subsidence become a crucial task, and the Persistent Scatterer Interferometric Synthetic Aperture Radar (PSInSAR) approach was applied to 120 Sentinel-1A images within three scenes, captured from October 2016 to October 2020 with the interval of 36 days between two consecutive images. This approach allows mapping ground displacement by continuously extracting deformation signals and estimating the position of targets that persistently scatter radar beams. The average velocity map shows that eight main subsidence areas in the Mekong delta have been affected in recent years with the maximum velocity of -39.61 mm year-1 and the cumulative displacement ranging from 60 to 100 mm in the Line Of Sight (LOS) direction over four years. The validation using 40 Sentinel-1B images, captured in identical periods indicates a consistent result in comparison with the one issued from Sentinel-1A. These pieces of knowledge are essential for improving both citizen’s life and reducing the impact of land subsidence on the natural environment.
MAPPING MULTI-SCALED LANDSCAPE TYPOLOGY OF LANG SON PROVINCE
Authors: Bui Thi Thanh Dung
Published: December 2021

The landscape of a territory is generated by natural components, and it is also influenced by human activities. The complexity of factors making up landscape and the relationship between them with humans has created a diverse and complex differentiation of landscape in Lang Son province. Three factors reflecting typical characteristics of Lang Son landscape: Digital Elevation Model (DEM), soil, and land cover have been selected in this study. The concept of multiscaled landscape classification based on the European Landscape Convention (ELC) is applied for combining the holistic with parametric approaches and combining typological with multi-scaled landscape classifications. A number of possible combinations between 9 land cover variables, 9 soil combination variables, and 5 topographic variables have yielded 40 landscape units for Lang Son province. The obtained results are basic documents for contributing to modern and practical landscape research on the one hand, and to territory planning for sustainable development of Lang Son on the other hand.
Effects of Boriding, Nitrocarburizing, Nitriding and Post-oxidation Treatments on The Tribological Properties of DIN 32CrMoV12-10 Steel
Authors: ÇEP Hasan , KOVACI Halim , ÇİMENOĞLU Hüseyin , ÇELİK Ayhan
Published: December 2021

In this study, the effect of different surface treatments was investigated to improve the friction and wear properties of DIN 32CrMoV12-10 steel. For this purpose, chrome plating, boriding, nitrocarburizing+oxidation, nitriding+oxidation processes were applied to the samples prepared from DIN 32CrMoV12-10 steel. After the procedures, the structural, morphological and mechanical properties of the samples were determined by XRD, SEM, hardness measurement device and profilometer. In order to determine the tribological properties of the samples, pin-on-flat wear tests were carried out. It was observed that a chromium layer was formed on the surface of the material after chrome plating. In boronized samples, it was observed that a boron layer was formed on the surface of the material and a diffusion layer was formed below it. The formed layers contain Fe2B and FeB phases. In nitrocarburized+oxidized and nitrided+oxidized samples, it was observed that the oxide layer on the material surface, a white layer just below it and a diffusion zone extending to the inner parts of the material were formed. The oxide layer formed on the surface consists of Fe2O3 and Fe3O4 phases, while the white layer and diffusion layers consist of ε-Fe2-3N and γ'-Fe4N phases. Due to the increased plastic deformation resistance with oxide layers, hard nitride phases and diffusion layers, the highest wear resistance was obtained from nitrocarburized+oxidized and nitrided+oxidized samples.
Changes in Composition, Antibacterial and Antifungal Activities of Mentha piperita Essential Oil During Storage
Authors: YEŞİL Meryem , ÖZCAN Mehmet Muharrem , KARA Şevket Metin , ERTÜRK Ömer
Published: December 2021

Abstract

In this study, effect of storage on chemical composition, antibacterial and antifungal activities of Mentha piperita L. essential oil was investigated. Essential oils of oven-dried plant samples were obtained by hydro-distillation, analyzed by gas chromatography/mass spectrometry and stored in a refrigerator at 4 ⁰C and in a freezer at -20 ⁰C for one, three and six months. Antibacterial and antifungal activity of the essential oils against some gram-positive (Bacillus cereus, Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus), gram-negative (Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Yersinia enterocolitica) bacterial strains and fungi (Candida albicans, Aspergillus niger) were evaluated by agar well diffusion method. Storage period antibacterial and antifungal activities of the essential oils increased. In general, essential oils stored at -20 ⁰C produced more antimicrobial activity than those stored at +4 ⁰C. The most affected microorganisms by essential oils were Staphylococcus aureus, Proteus vulgaris and Aspergillus niger. The results of the present study revealed that antibacterial and antifungal properties of Mentha piperita L. essential oil could be preserved and even improved when stored in proper temperature and period.
Maternal serum lactate dehydrogenase level and adverse pregnancy outcomes in women with hypertensive disorder of pregnancy at a tertiary care centre: a retrospective study
Authors: Ajila Disha , Raja Aishwarya , Ganiga Pradeep
Published: December 2021

Background: Hypertensive disorder of pregnancy affect 6-8% of all pregnancies, contributing immensely to maternal morbidity and mortality. Thus, presence of lactate dehydrogenase (LDH) signifies tissue damage and haemolysis. The aim of the study was to correlate LDH levels with blood pressure ranges and maternal and foetal outcome in women with gestational hypertension, pre-eclampsia.Methods: This retrospective study was conducted in the department of obstetrics and gynaecology of AJ Institute of Medical Sciences and Research Centre, Mangalore for a period of 1 year (January 2020 to January 2021). Based on the eligibility criteria, 52 hypertensive pregnant women were enrolled as cases.Results: Mean±SD period of gestation at delivery was lowest (34.57±1.39 weeks) for pregnant women with S. LDH levels>800 IU/l, whereas with S. LDH<00 IU/l delivered at around 37 weeks of gestation. Mean Apgar scores were lowest for the babies born to hypertensive pregnant women>800 IU/l, mean±SD Apgar scores at the end of 1 min, 5 minutes and 10 min were 4.42±0.79, 4.75±2.26 and 5.50±2.65 respectively.Conclusions: It can be concluded that S. LDH has the potential to be considered as a screening tool or predictor of the outcome of pregnancy in women with hypertensive disorders of pregnancy. However, studies of larger magnitude may be required to confirm the presence and the strength of association of S. LDH levels with pregnancy outcome.
Patterns of lipid profile abnormalities in hypertensive patients and normotensive subjects: a cross-sectional observational study
Authors: Mohan Chandra , Gururani Kunal , Rawat Anurag , Kala Mansi
Published: December 2021

Background: It is a well-known fact that hypertension and altered lipid profile or dyslipidaemia are leading risk factors for cardiovascular diseases. The coexistence of these two conditions has remained an interesting matter, among cardiologists and researchers alike. In this study, we analysed the serum lipid patterns of hypertensive patients and normotensive control subjects.Methods: This cross-sectional observational study was conducted in a tertiary healthcare and teaching center of Northwestern India during the period of 2010 and 2011. The study comprised of 100 hypertensive patients and 100 normotensive control subjects. Data were collected regarding demographic details, past medical/drug history and lipid profile including total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high-density lipoprotein (HDL).Results: A total of 200 subjects with the age above 20 years were enrolled in the study. The mean BMI in hypertensive patients (24.14±2.15 kg/m2) was significantly higher than normotensive subjects (22.60±2.62 kg/m2) (p<0.05). When we compared the mean of TC and TG among the hypertensive patients and normotensive subjects, highly significant differences were obtained (p<0.001). The significant decline in mean HDL level was observed in hypertensive patients than normotensive subjects (40.41±4.57 versus 44.64±5.97, p<0.005).Conclusions: The dyslipidaemia has been more evident among hypertensive patients. Hence, the measurement of blood pressure and lipid profile are of great importance to prevent cardiovascular diseases, stroke and other comorbidities.
Safety and efficacy of platelet rich plasma in the management of diabetic foot ulcer
Authors: Rani Raju , Priyanka Kathirvel
Published: December 2021

Background: Diabetic foot ulcers continue to pose a significant global issue despite the advances made in the management of diabetes. It causes major foot complications if they are not addressed properly. While several advancements have taken place in wound care management, platelet-rich plasma (PRP) promises to offer new hope in its management, aiding in cellular and tissue regeneration. Hence the present study was carried out to determine the safety and effectiveness of PRP in the management of diabetic foot ulcers in comparison to conventional dressing.Methods: This prospective study was focused on 50 diabetic foot ulcers, carried out in a surgical unit of Onsite Hospital, Chennai, Tamil Nadu from November 2018 to November 2019. Patients were divided into two groups group A received conventional ordinary dressing (n=25, 50%) and group B received PRP dressing (n=25, 50%). The mean follow up period was 6 weeks.Results: The present study observed that participants receiving PRP showed better wound contraction of 33.74% than the group receiving only conventional treatment with a mean wound contraction of was 12.82%. In addition, the duration required for wound contraction in the PRP group was short (mean value 4.488 cm) compared to the conventional dressing group (mean value 6.188 cm). The PRP group was found to be more effective in wound healing with fewer complications, less infection, exudates and pain.Conclusions: PRP is a powerful tool for the treatment of chronic wounds and very promising for diabetic foot wounds and it enables healing and reduces amputation rates, infection and exudates.
Clinical features, diagnosis, and types of optic neuritis
Authors: Hanafi Hany Abdelmoneim , Alghamdi Hanin Abdullah , Bassir Samir Sulaiman , Almutairi Salman Mubarak , Albalawi Athari Za’al , Aljaber Sara Adnan , Alyousif Abrar Abdullah , Almuraydhi Khaled Mohammed , Alsamadani Jumana Hamid , Aljadrawi Razan Ahmed , Matuk Fatemah Khawyter , Alsubaie Maha Fawaz , Alghamdi Yousef Saleh
Published: December 2021

Establishing a proper diagnosis and identifying the underlying etiology of optic neuritis can be challenging in clinical settings. This is due to the various subtypes and etiologies that were reported for the condition. However, conducting a thorough examination and the laboratory and imaging modalities can significantly enhance the diagnosis. Therefore, it is essential to be adequately aware of the different subtypes of optic neuritis and distinguish between the different clinical features and diagnostic findings of each subtype to conduct a proper diagnosis and enhance management of the affected cases. Optic neuritis is a severe condition that can lead to permanent vision loss. In the present literature review, we have discussed the potential clinical features and diagnostic findings of the different types of optic neuritis. More severe cases of optic neuritis are usually associated with NMOSD and IgG-MOG cases with a worsened prognosis. Painless and chronic vision loss might occur secondary to infections and granulomatous diseases. On the other hand, optic neuritis secondary to multiple sclerosis is usually self-limited. Many of the cases of optic neuritis are characterized by being responsive to steroid therapy. However, acute vision loss was also reported in some cases. Therefore, clinicians must be knowledgeable enough to conduct the most appropriate diagnostic and management modalities to enhance the prognosis of the affected patients. Further research is needed for optimizing the treatment plan and drawing better interventions.
Spatial analysis of COVID-19 in North Minahasa Regency of North Sulawesi Province
Authors: Kandou Grace D. , Ratag Budi T. , Sekeon Sekplin A. S. , Kandou Priscilla C.
Published: December 2021

Background: COVID-19 is an infectious disease that is currently a concern and has become a global problem. The trend in the number of confirmed cases and deaths due to COVID-19 every day is still increasing significantly. North Sulawesi Province currently has 7 regencies/cities which are declared as local transmission areas including North Minahasa Regency. The population density factor can affect the process of transmission of this disease. This study aims to determine the spatial description of the distribution of COVID-19 events in North Minahasa Regency.Methods: This quantitative research with descriptive observational design using a geographic information system approach. The location is in 10 sub-districts of North Minahasa Regency. Study population was all patients who were confirmed positive for COVID-19 based on data from the North Minahasa District Health Office as of 13 February 2021, as many as 1,273 cases. Simple random sampling was used and obtained 300 samples.Results: Results showed that the highest number of cases was for the age group 30-49 years (40%), female gender (54.7%), symptom onset date interval 4 days (26.7%), confirmation date grouped by month, namely October in 2020 (23%), the status of the patient recovered (86%), and there were no comorbidities (82%).Conclusions: Most of the cases of COVID-19 were found in densely populated areas and passenger transit areas between districts/cities. Policies on prevention and supervision of health protocols that are implemented must synergize across sectors and need to be improved.
Hearing impairment and associated socio-demographic characteristics in patients with tinnitus
Authors: Khan Danish A. , Varshney Pramod K. , Zubair M. Yasir , Anas M.
Published: December 2021

Background: Tinnitus is a common ear problem and causes various somatic and psychological effects that has a bearing on the quality of life. Considerably high prevalence, distressing nature of the problem and the fact that it is associated with hearing impairment warrants an early recognition and appropriate timely intervention.Methods: A total of 120 patients (60 with tinnitus and 60 without tinnitus) were included in the study. Data of putative socio-demographic factors and clinical examination findings were collected on a semi-structured questionnaire.Results: The mean age of patients with tinnitus was 38.12±13.39 while that of patients without tinnitus was 40.85±15.26 (p=0.299). Around two-thirds (63.33%, 95% CI, 51.3–75.7%) of patients with tinnitus were males and the other one-third (36.67%, 95% CI, 24.3–48.7%) were females. Two-thirds (66.7%, 95% CI, 54.6–76.7%) of patients with tinnitus belonged to urban locality and the remaining one-third (33.3%, 95% CI, 23.3–45.4%) were from rural areas. On pure tone audiometry (PTA), hearing impairment was detected in 32 (53.3%, 95% CI, 42.0–68.3%) patients with tinnitus as compared to 13 (21.7%, 95% CI, 9.3–35.4%) patients without tinnitus.Conclusions: Tinnitus was associated with hearing loss in considerable proportion irrespective of patients’ own awareness of hearing loss. Therefore, patients should be educated regarding importance of seeking early healthcare. Although the benefits of available treatments are small, and the perception of tinnitus does not wane completely, it improves quality of life and reduces distress resulting from tinnitus.
Las industrias creativas como agentes de innovación en Uruguay: descubrí el poder del vínculo
Authors: Pastorino Javier , Kimelman Nicole , Castillo Ana
Published: December 2021

En los últimos años las industrias creativas han ganado reconocimiento como sector productivo relevante a nivel mundial. Sin embargo, a pesar de que su potencial de desarrollo para la economía de Uruguay era significativo, las pequeñas y medianas empresas (pymes) de dicha industria no encontraban canales que les permitan innovar y desarrollar nuevos productos y modelos de negocio, en colaboración con otros sectores de la economía, en particular los de alta intensidad tecnológica. Por otro lado, también las pymes de sectores tradicionales, e incluso las tecnológicas, detectaban problemas en incorporar insumos creativos en sus procesos o productos finales.
Aggregated Results of OVE’s Annual Validation 2020: IDB Group's Evaluation Recommendations Tracking System (ReTS)
Authors: Maciel Odette , Arévalo Josette , Anderson Alonso Anais Maria , Infanzón Michelle , Barcellos Andreia , Putic Melanie , Ahumada Alejandro
Published: December 2021

OVE has issued 299 recommendations since the ReTS was launched in 2013. The Board has endorsed 288 of those (96%). In 2020, OVE assessed Management's action plans (APs) for 153 recommendations tracked in the ReTS, derived from 36 evaluations. 71% of the 153 recommendations were directed to IDB and the rest to IDB Invest or both.
Low Energy Consumption on Post-Moore Platforms for HPC Research
Authors: Rojas Yepes Pablo Josue
Published: December 2021

The increase in computational capacities has helped in the exploration, production and research process, this has allowed the use of applications that were infeasible years ago. This increase brings us a new Era (known as Post-Moore Era) and a wide range of promising devices, devices such as Single Board Computers (SBC) or Personal Computers (PC) that achieve performance that a decade ago was only found on a Server. This work presents high performance computing devices with low monetary cost and low energy cost that meet the needs for the development of research in Artificial Intelligent (AI) applications, in-situ data analysis and simulations that can be implemented on a large scale, these devices are compared in different tests, presenting advantages such as its performance per watt consumed, smart form, among others.
Actualización de la distribución geográfica de la serpiente índigo Drymarchon corais (Boie, 1827) en la Amazonía Ecuatoriana
Authors: Dueñas Manuel R.
Published: December 2021

Presentamos la actualización de la distribución geográfica de la serpiente índigo Drymarchon corais en la Amazonía ecuatoriana. Los datos presentados fueron obtenidos de la revisión de registros históricos, colección de especímenes en campo, revisión de especímenes en colecciones zoológicas, información de investigadores de campo y revisión de bases de datos de libre acceso. Nuestro estudio evidencia la presencia de la especie en localidades y en rangos altitudinales que anteriormente eran desconocidos. Además, presentamos datos de historia natural que permiten ampliar el conocimiento de la ecología de especie.
COVID-19 ResNet: Residual neural network for COVID-19 classification with bayesian data augmentation
Authors: Baldeon calisto Maria , Balseca Zurita Javier Sebastián , Cruz Patiño Martin Alejandro
Published: December 2021

COVID-19 is an infectious disease caused by a novel coronavirus called SARS-CoV-2. The first case appeared in December 2019, and until now it still represents a significant challenge to many countries in the world. Accurately detecting positive COVID-19 patients is a crucial step to reduce the spread of the disease, which is characterize by a strong transmission capacity. In this work we implement a Residual Convolutional Neural Network (ResNet) for an automated COVID-19 diagnosis. The implemented ResNet can classify a patient´s Chest-Xray image into COVID-19 positive, pneumonia caused from another virus or bacteria, and healthy. Moreover, to increase the accuracy of the model and overcome the data scarcity of COVID-19 images, a personalized data augmentation strategy using a three-step Bayesian hyperparameter optimization approach is applied to enrich the dataset during the training process. The proposed COVID-19 ResNet achieves a 94% accuracy, 95% recall, and 95% F1-score in test set. Furthermore, we also provide an insight into which data augmentation operations are successful in increasing a CNNs performance when doing medical image classification with COVID-19 CXR.
Automated Vigor Estimation on Vineyards
Authors: Pantoja Maria
Published: December 2021

Estimating the balance or vigor in vines, as the yield to pruning weight relation, is a useful parameter that growers use to better prepare for the harvest season and to establish precision agriculture management of the vineyard, achieving specific site planification like pruning, debriefing or budding. Traditionally growers obtain this parameter by first manually weighting the pruned canes during the vineyard dormant season (no leaves); second during the harvest collect the weight of the fruit for the vines evaluated in the first step and then correlate the two measures. Since this is a very manual and time-consuming task, growers usually obtain this number by just taking a couple of samples and extrapolating this value to the entire vineyard, losing all the variability present in theirs fields, which imply loss in information that can lead to specific site management and consequently grape quality and quantity improvement. In this paper we develop a computer vision-based algorithm that is robust to differences in trellis system, varieties and light conditions; to automatically estimate the pruning weight and consequently the variability of vigor inside the lot. The results will be used to improve the way local growers plan the annual winter pruning, advancing in the transformation to precision agriculture. Our proposed solution doesn\textsc{\char13}t require to weight the shoots (also called canes), creating prescription maps (detail instructions for pruning, harvest and other management decisions specific for the location) based in the estimated vigor automatically. Our solution uses Deep Learning (DL) techniques to get the segmentation of the vine trees directly from the image captured on the field during dormant season
Carta del editor
Authors: Cazar Dennis
Published: December 2021

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¿Cómo llegamos a la Performance Fronteriza?
Authors: Fortis Daril
Published: December 2021

Comparto una reflexión acerca de mi propio proceso de investigación sobre la historia de la práctica del performance en Tijuana (México) y la concepción del proyecto curatorial La performance fronteriza. Este explora la ‘desaparición‘ de las artistas/activistas, propiciada por la narrativa hegemónica del Arte Fronterizo conceptualizado ‘en‘ la frontera Tijuana-San Diego (EE. UU.), debido a su condición de ‘indocumentadas‘, a través de la rememoración colectiva del pasado del performance para diversificar la narrativa histórica de la práctica artística.
C U M B I A. cantos de resistencia / cantos migrantes
Authors: Arrieta Francisco
Published: December 2021

El siguiente texto es la huella escritural de un performance creado en 2019, enel que rastreo el origen de la cumbia como canto de resistencia y su adaptaciónen formas de existencia que actualizan las memorias ancestrales para bailar enla calle. En el texto acudo a voces cantadas, escritas, bailadas y susurradas, todasellas robadas, que invocan círculos de reconocimiento colectivo, a través de laliberación, el goce y el baile.

Parte de esta huella son enlaces a una selección de cantos que la acompañan parahacer bailar al lector mientras lee.
Desbordes/Undoing Borders: hacia nuevas epistemologías fronterizas
Authors: Burgos Hugo , Fellner Astrid M.
Published: December 2021

Desde que empezó la pandemia de Covid-19, el mundo ha sido testigo de otra fase en la proliferación de fronteras. La discusión sobre los roles complejos de los bordes, las fronteras y los límites se ha vuelto más relevante que nunca. Esta situación nos llama a reconceptualizar los procesos, discursos, prácticas y símbolos a través de los cuales funciona el poder de crear bordes.  Las fronteras, está claro, nunca son líneas estáticas, sino productos complejos en múltiples niveles. Incluso más si pensamos en cómo en la era posthumanista, el enfoque antropogénico limítrofe [bordering] ha llegado a sus límites (Konrad 2021), ya que nos enfrentamos con múltiples crisis ambientales y migratorias tanto a nivel local como transnacional. Teniendo en cuenta la importancia de los procesos fronterizos en el siglo XXI, este número de post(s) resalta las nuevas epistemologías fronterizas. Desbordes / Undoing Borders se enfoca en formas innovadoras de deshacer la frontera. Este número proporciona un espacio para investigaciones exploratorias de enfoques creativos de las fronteras, zonas y estados limítrofes, bordes permeables. post(s) 7 se enfoca en interacciones entre las manifestaciones materiales e inmateriales que ocurren en las fronteras y las diversas posibilidades de medios que existen para estudiarlas.
The Impact of Destination Image on Tourist Behavior: Karbala as a Case Study
Authors: Azeez Zuhier Abbas
Published: December 2021

The destination image is regarded as one of the elements affecting visitors' choices in selecting tourist locations that satisfy their wants and aspirations in a way that corresponds to their expectations of such places. The destination image influences tourist behavior by stimulating tourist desires to travel and engage in tourist activities, as well as influencing that behavior in the travel decision-making process during the pre-trip, trip, and post-trip phases. The destination image is also linked to visitor satisfaction with regard to their appraisal of their travel experience and the extent to which that experience meets or comes near to their earlier expectations. Therefore, the current study looks at the image and personality of religious, tourist, and commercial brands, as well as how they connect to future tourist behavior. The study considered Karbala city, Iraq, as a case study. The study was based on the in-filed study technique, which was represented by a questionnaire that was delivered to the study sample, which consisted of seven first-class hotels in Karbala city, with 40 copies of the questionnaire handed over to the administrative personnel at these hotels. The study discovered that the cognitive image, emotional image, and destination personality all had different effects on global image and behavioral intentions for first-time and recurrent visitors. Additionally, the findings show that the qualitative remarks focused heavily on attractions, culture, and the environment. The practical consequences are explored, and destination personality and behavioral outcomes for first-time and recurrent visitors were designed and evaluated independently.
Traditional Climate and Environment Forecasting Based on Local Knowledge of Urug Societies in Bogor West Java
Authors: Bahagia  , Mangunjaya Fachrudin Majeri , Mujahidin Endin , Wibowo Rimun
Published: December 2021

The aim of this research to find out about Indigenous of Knowledge Urug Community for forecasting climate and environment dynamic toward community resilience. The research method used is the ethnographic approach or cultural anthropology. Ethnography is sorts of qualitative research that need observation, documentary and interview in local societies. Ethnographic deal with discovers about description about culture including local knowledge, behaviour, cultural, ritual, traditional ceremonies, and language of Urug community. The selection of sample as informant exert purposive sampling technique. The result is probed meticulously through triangulation technique and triangulation sources. The result shows that the Indigenous community have implemented the sort of Traditional and calendar years with animals symbol for forecasting season and climate. The community can adapt season and climate dynamic and create community resilience for environment and climate. Besides that, there is the connection of planting local paddy to attaint community resilience including environmental change, cultural and social resilience.