bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemical changes in soil with use of pelletized organomineral fertilizer made from biosolids and sugarcane filter cake
Authors: Moreira João George , Delvaux Julio Cesar , Magela Mara Lúcia Martins , Pereira Vanderley José , Carmargo Reginaldo de , Lana Regina Maria Quintão
Published: May 2021

Soil fertility has become an interconnected aspect of modern agriculture, incorporating factors such as nutrient availability from soil, and its revision has become necessary for ensuring sustainability. Therefore, to understand the solubility of nutrients from organomineral fertilizers pelleted with biosolids and sugarcane filter cake, and to evaluate the resulting chemical changes in soil from its use, an experiment was performed in a completely randomized design. The experiment was done with four replicates in a 3 × 5 +1 factorial scheme, using three fertilizer sources (mineral fertilizer, organomineral fertilizer pelletized with biosolids, and organomineral fertilizer pelletized with the filter cake); five doses (60%, 80%, 100%, 120%, and 140% of the recommended dose of fertilization for corn); and an additional control treatment (absence of fertilization). The formulation of the organomineral fertilizers was 5-17-10 with 10% total organic carbon. All fertilizer sources were packed in a microfiber cloth positioned 1 cm below the surface of the soil and incubated for 60 days. Subsequent evaluation of chemical attributes: pH H2O (1:2.5); pH SMP (Shoemaker-McLean-Pratt); and the content of exchangeable aluminum, phosphorus, potassium, calcium, magnesium, silica, and organic matter within the soil was done. Organomineral fertilizers pelleted with biosolids or filter cake do not acidify the soil, but they were found to reduce aluminum saturation and promote a slow release of nutrients, which allowed a more balanced base in the soil. This then ensured a better balance of nutrients, with greater cation exchange capacity, base sums, and base saturation. The use of these fertilizers can contribute to stabilizing the pH of the soil with fewer applications of acidity correctives
Emergence and initial growth of Mimosa bimucronata (DC) O. KTZE. seedlings at different depths and position of sowing
Authors: Melo Luan Danilo Ferreira de Andrade , Junior João Luciano de Andrade Melo , Chaves Lívia Francyne Gomes , Rocha Dougllas Ferreira da , Neves Maria Inajal Rodrigues da Silva das , Gonçalves Edilma Pereira , Assis Wesley Oliveira de , Paes Reinaldo de Alencar , Medeiros Aldair de Souza , Magalhães Ivomberg Dourado , Crisostomo Natália Marinho Silva
Published: May 2021

Mimosa bimucronata (DC) O. KTZE. (maricá), belong to the family Fabaceae is a forest species found in Latin America. This species has been used in landscaping, reforestation and restoration of degraded areas and permanent preservation. The present work aimed to verify the effect of the position of the seed and the depth of sowing in the emergence and initial growth of seedlings of M. bimucronata. The experiment was carried out in a completely randomized design with four replications including 25 seeds per treatment. Different positions of the seeds were used in the sand substrate: downward facing (HB) thread; facing the side, forming an angle of 90 ° to the imaginary axis with the substrate (HL); and upward facing wire (HC), at seeding depths of 1, 2, 3, 4, 5 and 6 cm. The following variables were evaluated: emergence percentage, first count and emergence speed index, seedling length and dry mass. The results showed that HL at a depth of 1 cm sowing produces higher vigor seedlings.
Dynamics of formation and functioning of legume-rhizobial symbiosis Mesorhizobium ciceri-Cicer arietinum (variety Pam'iat')
Authors: Lohosha Olha , Vorobei Yuliia
Published: May 2021

The study of the dynamics of formation and functioning of symbiosis between nodule bacteria and chickpea plants was carried out in the northern region of Ukraine in the experimental plots, where the local population of chickpea mesorhizobia began to form. A new strain of Mesorhizobium ciceri ND-64 and a reference Mesorhizobium ciceri H-12 were used to inoculate Cicer arietinum seeds. The field study determined the number, weight, nitrogenase activity of nodules on the chickpea roots, dry green mass and mass of roots of chickpea plants of Pam'iat' variety. Samplings were carried out nine times in different phases of plant vegetation, starting from the branching phase and ending with the phase of complete maturity of seeds. The study showed that round and oval nodules appeared on the roots of chickpea plants during the branching stage. Gradually, they increased in size and in the phase of budding formed splices. The largest number of nodules (43.1 units/plant) was formed in the bean formation phase. The highest nitrogenase activity of the nodules was registered in the flowering phase. It was found that the bacterization of M. ciceri ND-64 promotes earlier formation and long-term functioning of the symbiotic apparatus in comparison with the reference strain and the control variant. The highest symbiotic rates under inoculation with M. ciceri ND-64 were registered at the beginning of the bean formation phase. In the control variant and with inoculation of M. ciceri H-12, these parameters were the highest later (at the end of the bean formation phase) and rapidly decreased in the subsequent phases, while the nodules formed by M. ciceri ND-64 continued to functioning actively. The positive effect of inoculation of chickpea seeds with a suspension of M. ciceri ND-64 on the increase in the number of beans and seeds per plant, weight of 1000 seeds and yield of chickpea plants was shown. Considering the obtained data, the new strain M. ciceri ND-64 is a promising bioagent of a microbial preparation for bacterization of chickpea
Metacogniciones sobre el dolor, la funcionalidad y la intensidad del dolor en mujeres con fibromialgia
Authors: Ortega-González Misleydis , Aguirre- Acevedo Daniel-Camilo , Jiménez-Benítez Mercedes
Published: May 2021

Determinar la capacidad explicativa de las metacogniciones y las creencias del dolor sobre la funcionalidad, el afrontamiento y la intensidad del dolor, siguiendo el Modelo de Funciones Ejecutivas de Autorregulación (FEAR) en una muestra de mujeres con fibromialgia de Medellín y su Área Metropolitana. Método: Se aplicaron: Escala de Metacogniciones acerca del Control de Síntomas, Cuestionario de Autoeficacia al Dolor, Escala de Catastrofización al Dolor Crónico, Cuestionario de Afrontamiento al Dolor Crónico, Escala WHODAS 2.0 y Escala numérica de la intensidad del dolor. La muestra estuvo representada por 108 mujeres entre 24 y 60 años con diagnóstico de fibromialgia. Se realizó un proceso de modilización por medio de un análisis de ecuaciones estructurales. Resultados: El modelo final no logra ajustarse. A pesar de ello, el análisis sugiere que las metacogniciones negativas y la autoeficacia al dolor tienen un efecto sobre la tendencia a la catastrofización. Esta última y la autoeficacia al dolor son las principales mediadoras en los efectos de funcionalidad. La intensidad del dolor no está determinada por las metacogniciones relacionadas con este.
Machine Learning based Psychology: Advocating for A Data-Driven Approach
Authors: Vélez Jorge I.
Published: May 2021

Since its beginnings, Psychology has been prone to both data generation and understanding of human behavior through data analysis. Back in 1879, Dr. Wilheim Wundt opened the first experimental psychology lab at the University of Leipzig to study reaction times. To many, this is considered the start of Psychology as a separate scientific discipline and the use of data analysis for data-driven decision making in the field (Flis, 2019; Tweney, 2003). In this Editorial, we briefly discuss how Psychology students, clinicians, and researchers may take part of the data revolution and help transforming Psychology, as we know it, into Machine Learning Psychology.
The effects of future climate change shocks on macroeconomic aggregates via agricultural production in Tunisia: A dynamic general equilibrium analysis
Authors: Zouabi Oussama
Published: May 2021

This study aims to analyze the direct and indirect impact of future climate changes on agricultural production and macroeconomic aggregates. A dynamic general equilibrium model of the Tunisian economy has been developed, which takes into account the effects of future climate shocks from 2020 to 2050 to assess the impact of future climate change on agricultural production and macroeconomic aggregates. The model is used to simulate various scenarios. The results of the climate shock simulations clearly show that long-term citrus fruits production is showing remarkable declines in the most citrus-producing governorates following a significant drop in water level in dams and level of groundwater table. In turn, cereals are the plants most affected by the long-term reduction in rainfall. As for the olive production, it would show a decline reaching –1.263% between 2020 and 2024 in the level of its production following reduction in rainfall. From a macro-economic point of view, climate change will result in the short- and long-term in a deterioration of certain quantities, notably household consumption, entrepreneurial investment, and the unemployment rate, which decreases by –0.139% between 2031 and 2040. These results underline the need for a long-term agricultural policy to reduce or limit the economic and social consequences of climate change and support economic development.
The choice of a marketing channel to benefit corn producer’s welfare in Indonesia
Authors: Ambo Upe Jusni , Aswan Andi
Published: May 2021

This study aims to examine the marketing channel optionsavailable for corn producers in South Sulawesi, the production center in Indonesia, as well as impact of such a choice on their income level. The target group was corn producers and corn traders. The total sample comprised 150 people, consisting of 120 corn producers and 30 corn intermediary traders within South Sulawesi Province. The results showed that three marketing channels accessed by producers are zero-level, one-level, and two-level channels. The net profit margin obtained by intermediary traders per kg is different by types for each marketing channel due to different marketing activities leading to different costs spent. The most efficient marketing channel is the zero-level channel that conducts direct selling to breeders. It followed by the one-level channel (from farmers to collectors and consumers). Finally, the two-level channel (from producers to merchant traders) showed the lowest efficiency. It should be mentioned that the zero-level channel offers a slight price increase for producers compared to other channels. Its consumers only buy limited number of products so that it does not have a wide impact on producer’s welfare. The study also found high input costs spent to cultivate corn due to land rent, fertilizers, and pesticides. AcknowledgmentThe welfare of corn producers and marketing channel choice is part of an internal research grant project from Hasanuddin University. The research involves the regional government at village and sub-district level, and farmer groups in villages within the Province of South Sulawesi.
Ultrasonic Pretreatment of Cowpea Bean Pod with K3PO4: Effect on Bio-Oil Yield and Phenolic Compounds Content
Authors: Bispo Diego , Santos Roberta , Granja Honnara , Freitas Lisiane
Published: May 2021

Ultrasonic pretreatment of cowpea bean pod biomass with addition of tripotassium phosphate (K3PO4) was used to induce the production of bio-oil enriched in phenolic compounds. An ultrasound bath operating at 40 kHz, 154 W power, and constant biomass:K3PO4 ratio of 5:1 (m/m) was used for pretreatments with different durations: 0.5, 1.5, 3, 6, 8, and 12 h. After the pretreatment, the biomass was pyrolyzed in a fixed bed reactor at 600 °C, under a flow of N2 at 5 mL min-1. The pyrolysis results indicated that the use of K3PO4 reduced the bio-oil yield, when compared to non-catalytic pyrolysis, and that the use of ultrasound caused increased biomass devolatilization, increasing the gas yield and reducing the formation of biochar. Gas chromatography mass spectrometry (GC-MS) analysis of the bio-oils indicated that pretreatment of the biomass led to significant increases of the phenolics contents, as well as alteration of the chemical profile of these compounds. The highest phenolics content of 8.12% m/m was obtained for the biomass submitted to 1.5 h of ultrasonic pretreatment, compared to 4.89% m/m for the untreated biomass.
Pemanfaatan Kulit Pisang Kepok (Musa paradisiaca ) dalam Pembuatan Bolu Kukus
Authors: Pangestika Aprilia Indah , Srimiati Mia
Published: May 2021

This study aims to determine the substitution effect of banana peel flour based on the proximate tests (water content, ash, carbohydrate, protein, fat and fiber). This experimental study used Completely Randomized Design (CRD) to find out the best quality of banana skin flour with the substitution level of kepok banana peel as a treatment. There were 4 treatments, F1 (45%), F2 (50%), F3 (55%) and F0 (without kepok banana peel flour). Based on the results of statistical tests using Analysis of Variance (ANOVA and Duncan’s Multiple Range Test, substitution of kepok banana peel flour has a significant effect (p 0.05) on the organoleptic properties. Steamed sponge cake substituted with 50% kepok banana peel flour (F2) was the formula with the highest acceptability compared to other formulas. Formula F2 (50%) showed the water content of 31,60%, ash level 2,78%, fat 5,97%, protein 10,97%, fiber 1,91%, and carbohydrate 48,68%. Kepok banana peel flour can be used as an alternative to diversification of food and increase the nutritional value of steamed sponge cake. Penelitian ini bertujuan untuk mengetahui pengaruh substitusi tepung kulit pisang kepok berdasarkan uji proksimat (kadar air, abu, karbohidrat, protein, lemak dan serat). Penelitian ini merupakan penelitian eksperimental menggunakan Rancangan Acak Lengkap (RAL) untuk mengetahui kualitas tepung kulit pisang terbaik dengan tingkat subsitusi tepung kulit pisang kepok sebagai perlakuan, yaitu F1 (45%), F2 (50%), F3 (55%) dan F0 (tanpa tepung kulit pisang kepok). Berdasarkan hasil uji statistik menggunakan Analysis of Variance (ANOVA) dan Duncan’s Multiple Range Test, substitusi tepung kulit pisang kepok berpengaruh signifikan (P0,05) terhadap hasil organoleptik produk. Bolu kukus yang disubstitusi tepung kulit pisang kepok sebanyak 50% (F2) merupakan formula dengan daya terima paling tinggi dibandingkan dengan formula lain. Formula F2 (50%) memiliki kadar air 31,60%, abu 2,78%, lemak 5,97%, protein 10,97%, serat 1,91%, karbohidrat 48,68%. Tepung kulit pisang kepok dapat dijadikan alternatif sebagai diversifikasi pangan dan meningkatkan nilai gizi pada bolu kukus.
Asupan Kalsium dan Fosfor Berkaitan dengan Karies Gigi pada Anak Sekolah
Authors: Damayanti Amilia Yuni , Darni Joyeti , Octavia Ruskiah
Published: May 2021

This study aims to determine the relationship between calcium and phosphorus intake with dental caries of school children. This study was an observational study with a cross sectional design. The sampling technique used purposive sampling, with a total sample of 96 subjects. This research was conducted in Madrasah Ibtidaiyah Nurussalam, Ngawi starting from April - May 2019. Data on dental caries status (DMF-T index) was obtained by dental examination by a dentist. Data on calcium and phosphorus intake were obtained by direct interviews regarding the amount and type of intake using the Semi-Quantitative Food frequency Quesionaire (SQFFQ) form and the 24 hour food recall form. Calcium and phosphorus data were processed using Nutrisurvey software and the Indonesian Food Composition Table (TKPI). Chi-square statistical tests were used to analyze the relationship between calcium and phosphorus intake and dental caries. The majority of MI students who experience caries are aged 10 and 11 years. Calcium and phosphorus intake of subjects was classified as inadequate (77,1% and 59,4%). There was a significant relationship between calcium intake with dental caries p = 0,031 (0,05) and phosphorus intake with dental caries p = 0,029 (0,05). Adequate intake of calcium and phosphorus can reduce the risk of dental caries in children. Penelitian ini bertujuan untuk mengetahui hubungan antara asupan kalsium dan fosfor dengan karies gigi anak sekolah. Penelitian ini adalah penelitian observasional dengan desain cross sectional. Tehnik pengambilan sampel menggunakan purposive sampling, dengan jumlah sample sebanyak 96 subjek. Penelitian ini dilakukan di Madrasah Ibtidaiyah Nurussalam, Ngawi mulai dari bulan April - Mei 2019. Data status karies gigi (indeks DMF-T) diperoleh dengan melakukan pemeriksaan gigi oleh dokter gigi. Data asupan kalsium dan fosfor diperoleh dengan wawancara langsung mengenai jumlah dan jenis asupan menggunakan form Semi-Quantitative Food frequency Quesionaire (SQFFQ) dan form food recall 24 hours. Data kalsium dan fosfor diolah menggunakan software Nutrisurvey dan Tabel Komposisi Pangan Indonesia (TKPI). Uji statistik Chi-square digunakan untuk menganalisis hubungan anatar asupan kalsium dan fosfor dengan karies gigi. Mayoritas Siswa MI yang mengalami karies adalah usia 10 dan 11 tahun. Asupan kalsium dan fosfor subjek masih tergolong kurang (77,1% dan 59,4%). Terdapat hubungan yang signifikan antara asupan kalsium dengan karies gigi p=0,031 (0,05) dan asupan fosfor dengan karies gigi p=0,029 (0,05). Asupan kalsium dan fosfor yang cukup dapat menurunkan resiko karies gigi pada anak.
Advances in Drug Discovery against Neglected Tropical Diseases: Human African and American Trypanosomiasis
Authors: Peerzada Mudasir Nabi , Gaur Aysha , Azam Amir
Published: May 2021

Human African and American trypanosomiasis are the vector-borne parasitic
diseases that have killed millions of people early, and many people are yet suffering from
these neglected diseases. The causative agents of these infections are parasitic protozoans
of the genus Trypanosoma. Current treatment regimens against these endemic diseases
have several limitations in terms of safety, efficacy, route of administration, and some of
them have lost efficacy due to the emergence of resistance in their respective parasites. In
this review, the most promising compounds identified by different strategies of drug development
against these neglected diseases including target-based approach, the phenotypic
high-throughput screening, the drug repurposing approach and combination therapy
are emphasized. The potent heterocyclic compounds currently undergoing pre-clinical or
clinical studies have also been assessed to ascertain an effective class of organic compounds
having significant therapeutic potential against these tropical diseases. The molecular
hybridization of outlined motifs may result in more active compounds and circumvent
the development of resistance by specific targets in future.
Intracranial Cerebrospinal Fluid Volume Evaluation in Healthy People and Hydrocephalus Patients using SPACE Sequence
Authors: Wu Xiaofeng , Richard Seidu A. , Xiangdong Xu , Lirong Zhang , Min Wu
Published: May 2021

Introduction:

Cerebrospinal Fluid (CSF) is produced mainly by the choroid plexus but
with a substantial influence by the ependymal lining of the ventricles in the brain. Hydrocephalus
occurs as a result of discrepancy in the production as well as circulation of CSF as a result of congenital
and acquired conditions. Nevertheless, studies on the differences between CSF dynamics according
to age and gender are still insufficient. Thus, this study evaluated the volume of intracranial
CSF in healthy people and hydrocephalus patients taking into account the differences between
CSF dynamics according to age and gender using Sampling Perfection with Application optimised
Contrast using different flip-angle Evolution (SPACE) sequence.

Methods:

120 healthy volunteers and 60 patients with hydrocephalus were included in this study.
SPACE sequence was used to evaluate intracranial CSF with a 3.0T magnetic resonance machine.
The total volume of intracranial CSF and the amount of CSF in the ventricle were obtained using a
software, and the volume ratio of CSF in the subarachnoid space, the ventricle and the subarachnoid
space were calculated.

Results:

The mean volume of intracranial CSF, ventricular CSF, and subarachnoid CSF of male
volunteers were (206.9±47.7) cm3, (33.0±10.7) cm3, (173.9±37.9) cm3 respectively. The average
volume of intracranial CSF, ventricular CSF, and subarachnoid CSF of female volunteers were
(199.7±44.9) cm3, (30.8±9.4) cm3, and (168.9±37.0) cm3, respectively. Thus, no significant statistically
(P>0.05) difference between males and females was found. (3) The mean values of intracranial
CSF, ventricle CSF and subarachnoid CSF, ventricle and subarachnoid CSF volume ratio in patients
with hydrocephalus were significantly greater than health volunteers. Thus, the difference between
the two groups was statistically significant (P<0.05).

Conclusion:

SPACE sequence can quantitatively determine the content of CSF. The change of
CSF volume has nothing to do with gender but with age. It is feasible to use SPACE sequence to
evaluate the spatial distribution and volume of intracranial CSF.
El cuerpo contra la pared
Authors:   Universidad de Bogotá Jorge Tadeo Lozano, Vargas Rodríguez Felix Alberto
Published: May 2021

El cuerpo contra la pared es una lectura de las representaciones del cuerpo humano en la imagen grafiti con los lentes de la historia del arte, la estética, la sociología y la literatura; exploradas con el propósito de tratar de comprender algo del universo social y cultural contemporáneo. Dentro del amplio espectro de la imagen grafiti se destaca una prolífica vertiente en la que el motivo de representación primordial es el cuerpo humano. Pintadas, estarcidas, adheridas sobre las paredes, esas imágenes son efímeros tatuajes en la piel urbana; en ellas el cuerpo se convierte en una forma de lenguaje por medio del cual se plasman desde mensajes publicitarios hasta diatribas sobre el statu quo, y desde opiniones y deseos individuales hasta imaginarios colectivos.
Factors That Help and Hinder the Implementation of Digital Depression Prevention Programs: School-Based Cross-sectional Study
Authors: Beames Joanne R , Johnston Lara , O'Dea Bridianne , Torok Michelle , Christensen Helen , Boydell Katherine M , Werner-Seidler Aliza
Published: May 2021

Background

Digital prevention programs that are delivered in a school environment can inoculate young people against depression. However, little is known about the school-based factors that help and hinder the implementation of these programs. Staff members are integral for supporting mental health programs in schools and are likely to have a wealth of expertise and knowledge about the factors that affect implementation.

Objective

The primary objective of this study was to explore the barriers and facilitators to implementing a digital depression prevention program in Australian secondary schools with teachers, counselors, and principals. The secondary objective was to explore variations in these factors across different school contexts, including the school type (government or nongovernment), location (capital city, regional/or rural areas), and socioeconomic status (SES) (low, medium, high).

Methods

This quantitative cross-sectional survey study assessed the barriers and facilitators to implementing a hypothetical digital prevention program in Australian schools. The survey was taken by 97 teachers (average age 38.3 years), 93 counselors (average age 39.5 years), and 11 principals (average age 50.9 years) across Australia between November 2017 and July 2018.

Results

A range of barriers and facilitators relating to logistics and resources, staff support, and program factors were endorsed by the surveyed staff. Consistent with prior research, common barriers included a lack of time and resources (ie, staff and rooms). These barriers were particularly evident in government, rural/regional, and low socioeconomic schools. Other barriers were specific to digital delivery, including privacy issues and a lack of clarity around staff roles and responsibilities. Facilitators included upskilling staff through training, embedding the program into the curriculum, and other program factors including universal delivery, screening of students’ mental health, and clear referral pathways. Knowledge about the program efficacy was also perceived as important by a large proportion of the respondents.

Conclusions

The digital depression prevention program was perceived as suitable for use within different schools in Australia, although certain factors need to be considered to enable effective implementation. Logistics and resources, support, and program factors were identified as particularly important for school-based implementation. To maximize the effectiveness in delivering digital programs, implementation may need to be tailored to the staff roles and school types.
Artificial Intelligence–Based Prediction of Lung Cancer Risk Using Nonimaging Electronic Medical Records: Deep Learning Approach
Authors: Yeh Marvin Chia-Han , Wang Yu-Hsiang , Yang Hsuan-Chia , Bai Kuan-Jen , Wang Hsiao-Han , Li Yu-Chuan Jack
Published: May 2021

Background

Artificial intelligence approaches can integrate complex features and can be used to predict a patient’s risk of developing lung cancer, thereby decreasing the need for unnecessary and expensive diagnostic interventions.

Objective

The aim of this study was to use electronic medical records to prescreen patients who are at risk of developing lung cancer.

Methods

We randomly selected 2 million participants from the Taiwan National Health Insurance Research Database who received care between 1999 and 2013. We built a predictive lung cancer screening model with neural networks that were trained and validated using pre-2012 data, and we tested the model prospectively on post-2012 data. An age- and gender-matched subgroup that was 10 times larger than the original lung cancer group was used to assess the predictive power of the electronic medical record. Discrimination (area under the receiver operating characteristic curve [AUC]) and calibration analyses were performed.

Results

The analysis included 11,617 patients with lung cancer and 1,423,154 control patients. The model achieved AUCs of 0.90 for the overall population and 0.87 in patients ≥55 years of age. The AUC in the matched subgroup was 0.82. The positive predictive value was highest (14.3%) among people aged ≥55 years with a pre-existing history of lung disease.

Conclusions

Our model achieved excellent performance in predicting lung cancer within 1 year and has potential to be deployed for digital patient screening. Convolution neural networks facilitate the effective use of EMRs to identify individuals at high risk for developing lung cancer.
Get Waivered Remote: Use of Social Media Platforms to Promote Virtual DEA-X Waiver Course Enrollment (Preprint)
Authors: He Shuhan , Balapal Neha , Kannikal Jasmine , Chong Paul , Shyamsundar Saishravan , Kallenberg Nick , Balaji Adarsh , Martin Alister , Ankem Amala
Published: May 2021

BACKGROUND

Social media use by the public is at an all-time high and provides a convenient method of reaching broad audiences for public health agendas. Despite this, quantifying the impact of social media on health campaigns has proven to be a challenge, largely due to a lack of consistency in the metrics used, which can be unclear and variably effective. GetWaivered.com (GW) delivers and hosts free nationwide, remote DEA-X waiver training courses that enable clinicians to obtain their DEA-X so that they are able to prescribe Buprenorphine and effectively treat Opioid Use Disorder (OUD). Evaluating Get Waivered social media engagement can be key to increasing awareness of our course.

OBJECTIVE

This paper aims to evaluate the use of social media platforms such as Facebook, Twitter, and WordPress for raising awareness of obtaining a DEA-X Waiver by determining the reach and engagement of the social media program.

METHODS

The intended target of the social media postings were clinicians who were eligible to prescribe buprenorphine. For our preliminary evaluation, we analyzed Facebook ads, Twitter, and Google Analytics data to measure engagement with our course advertisements. Twitter data such as impressions, engagements, engagement rate, and interactions (tweets, retweets, replies, likes) was assessed using exported excel data from Twitter Analytics and analyzed on Microsoft Word Excel. Facebook Ads reach, engagement, reactions, comments, shares, post clicks, cost, and cost per post engagement/event response/link click were assessed with Python using data from the Facebook platform. Google analytics data from the Google Analytics platform was used to analyze engagement metrics for the Get Waivered website.

RESULTS

Twitter posts generated a total of 16,643 impressions and 291 engagements. Facebook Ads generated a total of 36,008 reach, 6,173 engagement, and 321 clicks. Google Analytics showed that the WordPress blog (Get Waivered website) had a 477.80% increase in total users, a 475.10% increase in new users, 390.61% increase in sessions, and a 219.59% increase in page views between comparison periods.

CONCLUSIONS

This evaluation shows that social media posting does garner engagement while being more convenient than traditional forms of advertising. Since methods for analyzing social media use in public health is varied, these preliminary findings set a basis for developing social media posting structure and evaluation for future projects. The use of Twitter analytics and Facebook Ad insights allows GW to track which posts have large engagements and how to better interact with Twitter and Facebook users. This evaluation provides preliminary data and a framework as a baseline for planned future studies.
Conflicts of Interest in “Throwaway” Dermatology Publications: Analysis of the Open Payments Database (Preprint)
Authors: Roman Jorge , Elpern David J
Published: May 2021

BACKGROUND

Dermatology journals, periodicals, editorials, and news magazines are influential resources that are not uniformly regulated and subject to influence from the pharmaceutical industry. This study evaluates industry payments to physician editorial board members of common dermatology publications, including “throwaway” publications.

OBJECTIVE

The aim of this study was to characterize the extent and nature of industry payments to editorial board members of different dermatologic publications in order to ascertain differences in payments between different types of publications.

METHODS

A list of editorial board members was compiled from a collection of clinical dermatology publications received over a 3-month period. Data from the Open Payments database from 2013 to 2019 were collected, and analysis of payments data was performed.

RESULTS

Ten publications were evaluated, and payments data for 466 physicians were analyzed. The total compensation across all years was US $75,622,369.64. Consulting, services other than consulting, and travel or lodging payments constituted most of the payments. A fraction of dermatologists received the majority of payments. The top payers were manufacturers of biologic medications. Payment amounts were higher for throwaway publications compared to peer-reviewed journals.

CONCLUSIONS

Editorial board members of dermatology publications received substantial payments from the pharmaceutical industry. A minority of physicians receive the lion’s share of payments from industry. “Throwaway” publications have more financial conflict of interest than do peer-reviewed journals. The impact of these conflicts of interest on patient care, physicians' practice patterns, and patient perception of physicians is noteworthy.
Modulation of Bone and Joint Biomarkers, Gut Microbiota, and Inflammation Status by Synbiotic Supplementation and Weight-Bearing Exercise: Human Study Protocol for a Randomized Controlled Trial (Preprint)
Authors: Ilesanmi-Oyelere Bolaji Lilian , Roy Nicole C , Kruger Marlena C
Published: May 2021

BACKGROUND

There is strong evidence suggesting that prebiotics and probiotics regulate gut microbiota, reducing inflammation and thereby potentially improving bone health status. Similarly, mechanistic evidence suggests that either low-impact or high-impact weight-bearing exercises improve body composition and consequently increase bone mineral density in individuals with osteoporosis and osteoarthritis.

OBJECTIVE

This study aims to investigate the effects of a synbiotic (probiotic+prebiotic) supplementation, an exercise intervention, or a combination of both on gut microbiota, inflammation, and bone biomarkers in postmenopausal women.

METHODS

A total of 160 postmenopausal women from New Zealand will be recruited and randomized to one of four interventions or treatments for 12 weeks: control, synbiotic supplementation, exercise intervention, or synbiotic supplementation and exercise. The primary outcome measure is the bone and joint biomarkers at baseline and week 12, whereas the gut microbiota profile and inflammatory cytokine measurements will serve as the secondary outcome measures at baseline and week 12. Baseline data and exercise history will be used to assess, allocate, and stratify participants into treatment measures.

RESULTS

Recruitment of participants will begin in September 2021, and the anticipated completion date is June 2022.

CONCLUSIONS

To the best of our knowledge, this will be the first randomized controlled trial to analyze the effects of both a synbiotic supplement and an exercise intervention in postmenopausal women. On the basis of the results obtained, a combination of synbiotic supplements and exercise might serve as a noninvasive approach to manage and/or improve body composition and bone health in postmenopausal women.

CLINICALTRIAL

Australian New Zealand Clinical Trials Registry ACTRN12620000998943p; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380336&isClinicalTrial=False
The Psychiatric Burden in Pregnant and Postpartum Women during the COVID-19 Pandemic: A Clinical Snapshot (Preprint)
Authors: Venkatesan Kirthika , Chaudhary Maimona , Patel Sruti , Chaudhry Faatir
Published: May 2021

UNSTRUCTURED

The coronavirus disease-2019 (COVID-19) or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was declared a pandemic in March 2020 by the World Health Organization (WHO). The virus spreads through fomites and air transmission causing mild upper respiratory tract infection, severe acute respiratory distress, neurologic deficits, and death. The pandemic has been stressful for many, especially for pregnant and postpartum women. Since the transition to motherhood is challenging, pandemic-related factors have created an increase in the risk of mental health burden and psychiatric disorders in this cohort. This is attributed to a combination of neuroendocrine factors and pandemic-related factors such as quarantine, remote healthcare consultations, domestic violence, and the fear of infection. It is important to identify and treat mental health disorders in this cohort due to the negative impact on the mother and child, neurological changes (i.e. changes in gray matter volume) in patients with chronic psychiatric disorders, and the risk of self-harm/suicide. Here we review the current knowledge of psychiatric disorders in pregnant and postpartum women during the COVID-19 pandemic and consider potential future research.
Correction: Benchmarking Triage Capability of Symptom Checkers Against That of Medical Laypersons: Survey Study (Preprint)
Authors: Schmieding Malte L , Mörgeli Rudolf , Schmieding Maike A L , Feufel Markus A , Balzer Felix
Published: May 2021

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Effects of computer-based feedback and formative assessment on learning outcomes
Authors: Ngo Van Thien
Published: May 2021

The purpose of the study is to examine the effect of student response systems in computer-based feedback and formative assessment on learning outcomes. The backward design course is a tool to be applied for collecting necessary assessment evidence. The quasi-experimental research design involves collecting pretest and posttest data on students assigned to the control and the experimental group. The sample group consists of 148 college students randomly selected from two of the eight classes of electrical and electronics students at Cao Thang Technical College in Ho Chi Minh City, Vietnam. The research findings revealed that the experimental group, in which student response systems were applied, got better results than the control group, who did not apply them. Results show that using student response systems for technology-based feedback and formative assessment is vital and meaningful not only for teachers but also for students in the teaching and learning process.
Bimetallic CuCo-Zeolitic imidazole frameworks (CuCo-ZIFs): Synthesis and characterization
Authors: Dang Huynh Giao , Truong Tuong Vi , Ho Thi Thu Ngan , Nguyen Van Binh , Ho Ngoc Tri Tan , Pham Van Toan
Published: May 2021

A kind of bimetallic Cu/Co zeolitic imidazole frameworks (CuCo-ZIFs) has been successfully synthesized in ethanol solvent by ultrasound method. The morphology, structural features and physicochemical properties of CuCo-ZIFs were analyzed by several techniques including powder X-ray diffraction, thermo-gravimetric analysis, Fourier-transform infrared spectroscopy,, energy-dispersive X-ray spectroscopy, scanning electron microscope, and nitrogen physisorption measurements. The results showed that CuCo-ZIFs nanocrystals demonstrated a ZIF-67-like polyhedral morphology with high thermal stability. The Brunauer-Emmett-Teller surface areas of CuCo-ZIFs were achieved approximately 1172 m2/g, while its Langmuir surfaces areas were achieved approximately 1907 m2/g.
Conocimiento médico psiquiátrico: preguntas desde la epistemología social
Authors: Gómez-Aguilar Iván Eliab
Published: May 2021

Este trabajo expone la utilidad de la epistemología social para estudiar los conocimientos expertos, tales como el que utiliza la psiquiatría contemporánea. En la primera parte explico en qué consiste la epistemología social y señalo algunos compromisos mínimos de su enfoque. En la segunda parte abordo una serie de problemas que desde la epistemología social pueden investigarse en torno a la aplicación y generación del conocimiento médico psiquiátrico. Para ello, distingo tres escenarios que refieren a niveles sociales distintos: el de la interacción entre personas, el de las instituciones sociales y el de la producción de recursos hermenéuticos. Señalo finalmente en qué sentido la epistemología social puede abordar para cada nivel, respectivamente: a) la injusticia epistémica testimonial en los escenarios de interacción entre psiquiatras y usuarios de la psiquiatría, b) las tensiones en la construcción de categorías diagnósticas sobre trastornos mentales realizadas por grupos de expertos, y c) la injusticia hermenéutica a la que están sujetas otras formas de nombrar las experiencias que desde la psiquiatría se denomina «trastorno mental».
Cambios fisiológicos durante el embarazo normal
Authors: Carrillo-Mora Paul , García-Franco Alma , Soto-Lara María , Rodríguez-Vásquez Gonzalo , Pérez-Villalobos Johendi , Martínez-Torres Daniela
Published: May 2021

The woman's body undergoes a series of physiological changes at all levels that hace the purpose of adapting and responding to the the 40 weeks of gestation. These changes occur gradually, but in a continuously, throughout the pregnancy and range from cardiovascular, digestive, pulmonary, hematological and endocrine changes, which at the end also end up gradually reversing during the puerperium. The physiological changes are related to the development of different symptoms, signs and alterations in the pregnant woman, as well as changes in the parameters of the paraclinical studies, which makes it especially relevant for the general practitioner or first contact doctor to recognize these changes and the moment in which they occur in pregnancy so that they can make a timely identification of the alterations that can represent pathological states that are a threat to maternal and fetal well-being. For all of the above, the objective of this thematic review was to collect and describe the main physiological changes that occur in women during a normal pregnancy, as well as the changes that occur in the most common paraclinical studies.
Keywords: Pregnancy; physiology; anatomy; cardiovascular; hematological; paraclinical studies
Age constraints on host rocks of Los Uvares gold deposit: Magmatic pulses in southernmost Baja California, Mexico.
Authors: Carrillo Chávez A. , Huyck H. , Zentilli M. , Griest A.
Published: May 2021

El yacimiento epitermal de oro diseminado de Los Uvares, localizado en la parte central del bloque Cabo San Lucas (CSLB) en la parte sur de la península de Baja California, ocurre en una tonalita cataclástica intrusionada por alaskita y diques parcialmente fracturados de diorita. Las edades isotópicas de potasio-argón (K-Ar) en hornblendas separadas de rocas intrusivas relativamente no alteradas en Los Uvares son: 137 Â± 6 Ma (tonalita) y 128 Â± 5 Ma (diorita). Las edades K-Ar son internamente consistentes con las edades relativas de la diorita y la tonalita derivadas de las relaciones de campo e indican un evento magmático Cretácico. Estas edades son más antiguas que las determinadas previamente para rocas similares del CSLB (rango: 109-42 Ma). Existen varias posibles explicaciones para la diferencia de edades; sin embargo, es muy probable que el yacimiento de Los Uvares ocurra en un complejo intrusivo que representa una fase más antigua (no reportada previamente) del pulso magmático Cretácico-Terciario del CSLB. Las edades de trazas de fisión en apatitas de los diques de diorita varían de 80 a 100 Ma. Estas edades sugieren que la actividad hidrotermal en Los Uvares culminó hace ~ 80 Ma, para posteriormente continuar con las etapas de enfriamiento/erosión.
Distributions of stresses and geometry of the Wadati-Benioff zone under Chiapas, Mexico
Authors: Rebollar Cecilio J. , Espíndola Victor H. , Mendoza Antonio , Pérez-Vertti Arturo
Published: May 2021

La sismicidad registrada desde junio de 1994 a mayo de 1995, en una red portátil de estaciones sismológicas analógicas y digitales, definieron la geometría de la zona Wadati-Benioff bajo Chiapas, así como la distribución de los esfuerzos principales en la placa subducida. La sismicidad localizada en el antearco no fue bien localizada. Un módulo de Poisson de 0.24 fue calculado para la corteza de Chiapas. 321 sismos fueron localizados en el rango de magnitudes entre 3.3 y 5.6. Los hipocentros definieron la zona Wadati-Benioff de 39Â±4 km de grueso buzando 40°Â±3° hacia N45°E. La profundidad de los sismos varió entre 10 a 300 km. La placa de Cocos buza aproximadamente 25° en Oaxaca, 30° bajo el Golfo de Tehuantepec y 40° hacia el sudeste. Un fuerte cambio en el buzamiento de la placa de Cocos ocurre en la intersección de la cordillera de Tehuantepec y la Trinchera de Centro América. La sismicidad en esta zona es difusa hasta profundidades de 200 km. Nuestros datos sugieren un incremento gradual del buzamiento de la placa de Cocos de Oaxaca a Chiapas. Los mecanismos focales de eventos con profundidades menores de 50 km indican que la placa subducida está bajo tensión, mientras que a profundidades entre 50 y 200 km la placa experimenta un régimen mixto de esfuerzos. A profundidades entre 200 y 300 km la litosfera subducida está bajo un régimen comprensivo en la dirección del buzamiento.
On the existence of solar variations in the 16th to 18th centuries
Authors: Schröder W. , J. Treder H.
Published: May 2021

Una revisión de las mínimas de actividad solar y la relación entre la actividad auroral y geomagnética nos permiten establecer que la actividad mínima solar no es evidente en los datos disponibles.
Lyt til borgerne – hvis I vil lykkes på tværs
Authors: Digmann Annemette
Published: May 2021

Ledelse og samarbejde på tværs af fag, afdelinger og sektorgrænser er kommet for at blive. Oftere og oftere oplever borgere, at de kommer i klemme mellem systemer, der ikke er i stand til at arbejde på tværs. For at blive klogere på vanskelighederne og hvordan de kan overkommes, har jeg fulgt adskillige ’på tværs’ samarbejder gennem en årrække. Denne artikel bygger på, at jeg gennem en længere periode har fulgt Psykiatriens Hus i Aarhus, der er et tilbud, der forsøger at bygge bro mellem den regionale behandlingspsykiatri og socialpsykiatrien i kommunen.

 

Artiklen begynder med en beskrivelse af den aktionslæring, der foregik i samarbejde med ledelsen i 2019 og slutter med den analyse som aktionsforskningen bidrog med i løbet af 2020. Artiklen beskriver hvordan ledelsen i Psykiatriens Hus forsøger at omsætte den viden, der findes om ledelse på tværs, til praktiske handlinger. En hovedkonklusion er, at det lykkes at samarbejde på tværs, når man tager udgangspunkt i borgerperspektivet.
Digitaliseringens frontløbere i værdiskabelse: Autentiske aktører og digitale agenter
Authors: Pedersen Mogens Kuhn
Published: May 2021

Alle brugere af digitale medier bevæger sig i informationssamfundet, hvor der er nye muligheder og spilleregler for værdiskabelse sammenholdt med de kendte fra den analoge verden. Artiklen belyser:

 

Digitale agenter fremkommet igennem det seneste årti er de nye “indbyggere” i informationssamfundet. De har ikke direkte reference til autentiske personer. Hvordan kan vi forstå deres betydning for såvel analog som digital kommunikation og sociale relationer? (Afsnit A)

 

Hvilken form for værdiskabelse er knyttet til de digitale agenter og agens? (Afsnit B)

 

Hvilke værdiskabende muligheder og konsekvenser indebærer digital agens: Eksempler (Afsnit C)

 

Hvilke er de socio-økonomiske udviklingsmuligheder med digital agens? (Afsnit D)

 

Hvilke regulatoriske udfordringer stiller de digitale agens til virksomheder og til samfundet? (Afsnit E)

 

I artiklen behandles disse spørgsmål ud fra samfundsvidenskabelige teorier om digitalisering, værdiskabelse og regulering.
Global Longitudinal Strain as a Predictor of Chemotherapy-Induced Cardiotoxicity
Authors: Avila Monica , Alves Marco , Ayub-Ferreira Silvia , Junior Mauro Wanderley , Cruz Fatima , Brandão Sara Michelly , Hajjar Ludhmila , Filho Roberto Kalil , Cruz Cecilia , Abduch M. Cristina , Moleta Danilo , Bocchi Edimar
Published: May 2021

Background: Chemotherapy-induced cardiotoxicity (ChC) is an important
complication among patients receiving anthracyclines. Biomarkers and
imaging parameters have been studied for their ability to identify
patients at risk of developing this complication. Left ventricle global
longitudinal strain (LV-GLS) has been described as a sensitive parameter
for detecting systolic dysfunction, even in the presence of preserved
left ventricle ejection fraction (LVEF). Objective: to evaluate the role
of the LV-GLS as a predictor of ChC. Methods: This study is a post-hoc
analysis of CECCY trial (Carvedilol for Prevention of
Chemotherapy-Related Cardiotoxicity) that evaluated the primary
prevention of cardiotoxicity with carvedilol during doxorubicin
chemotherapy in a population with breast cancer. Cardiotoxicity was
defined as a reduction >10% in LVEF. LV-GLS was obtained
before chemotherapy in patients with no prior cardiovascular disease or
echocardiogram abnormalities. Results: Thirty-one patients who had a
complete echocardiography study including measurement of LV-GLS before
chemotherapy were included in this analysis. An absolute LV-GLS
<16.9% before chemotherapy showed 100% sensitivity and 73%
specificity for predicting cardiotoxicity (AUC=0.85; 95%CI 0.680 –
0.959, p<0.001). In this population, LVEF values before
chemotherapy did not predict ChC (95%CI 0.478 to -0.842, p=0.17). The
association of low LV-GLS (<17%) and BNP serum levels
(>17 pg/mL) two months after chemotherapy increased the
accuracy for detecting early onset ChC (100% sensitivity, 88%
specificity, AUC=0.94; 95%CI 0.781 – 0.995, p<0.0001).
Conclusions: Our data suggest that LV-GLS is a potential predictor of
chemotherapy-induced cardiotoxicity. Larger studies are needed to
confirm the relevance of this echocardiographic parameter in this
clinical setting.