bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on the role of \(\textit{TDRD1}\) variants in male infertility among 310 Vietnamese individuals
Authors: Duc Duy La , Minh Nguyet Nguyen , Thi Thu Hue Huynh , Thuy Duong Nguyen
Published: July 2023

Infertility is a global reproductive health burden affected by various genetic factors, including spermatogenic defects. The instability of the germ cells’ genome caused by the unregulated replication of transposable elements is one of the causes of spermatogenic impairment. Tudor domain-containing 1 (TDRD1) expressed only in germ cells plays a significant role in the piRNA (PIWI-interacting RNA) pathway to maintain genome integrity via suppressing transposon elements during spermatogenesis. Despite the protein’s role in male germline development, TDRD1 has not been studied intensively. In this study, we established the relationship between male infertility and single nucleotide polymorphisms (SNPs) of TDRD1 (rs541192490, rs77559927) among 310 Vietnamese men (160 infertile patients and 150 healthy controls). Genotypes of single nucleotide polymorphisms of the TDRD1 gene (SNPs) were identified using the PCR-RFLP method. The results showed that TDRD1 SNPs were not associated with male infertility in all three test models (additive, dominant, and recessive) (p-value > 0.05). Haplotype analysis of the two SNPs also showed similar findings. This study would contribute to the knowledge of TDRD1’s association with male infertility in the Vietnamese population.
Association of the 65-bp indel polymorphism in \(\textit{GOGLB1}\) gene with body weight of Vietnamese Noi chickens
Authors: Dieu Thuy Nguyen Thi , Quynh Mai Vu , Anh Khoa Do Vo
Published: July 2023

Noi chicken is one of the indigenous fighting-cock breeds of Vietnam with many valuable properties. In chicken, the Golgin subfamily B member 1 (GOLGB1) gene, which locates on chromosome 1, encodes the coat protein 1 vesicle inhibiting factor. A previous study showed that the 65-bp insertion/deletion in the GOLGB1 gene was significantly associated with chicken body weight, neck weight, abdominal fat weight, abdominal fat percentage and the yellow index b of the breast in Chinese indigenous chicken (N409-breed). In this study, 65-bp indel polymorphism in the GOLGB1gene was evaluated in association with body weight in Noi chickens. The live body weight of 170 chickens (90 females, 80 males) at continuous ages of 7-day intervals (from 28 to 84 days) was recorded. A 65-bp indel polymorphism in the GOLGB1 gene was analyzed using the PCR method. The results of PCR and sequencing revealed two alleles (I and D) corresponding to three genotypes: II, ID, DD, in which, the I allele appears with the highest frequency (0.79) in the studied population. An association study using Minitab software showed that genotype was significantly associated with body weight in Noi chickens at days 35 to 84 (P < 0.05). Individuals with more allele “I” have higher live body weight than others. Both factors (sex and genotype) simultaneously affected the body weight of Noi chickens. The results of this study suggested that the 65-bp indel in the GOLGB1 gene could be considered a potential marker for Noi chicken breeding.
Experience in a Standardized Algorithm for Surgical Treatment of Patients with Mandibular Fractures
Authors: Pankratov Alexander S. , Gotsiridze Zauri P. , Kurshina Svetlana I. , Karalkin Anatoly V. , Grinin Vasily M. , Valieva Leyli U.
Published: July 2023

Background. In recent decades, new surgical technologies for the treatment of patients with mandibular fractures have been introduced into clinical practice. However, the incidence of complications still remains high, practically not differing from the values 30 years ago. According to the Russian Dental Association, the incidence of complications is 1519%. Probably, the introduction of rules governing the use of new methods of treatment can change the current situation for general clinical practice. Aims to evaluate the effectiveness of the algorithm for the surgical treatment of patients with mandibular fractures, developed on the basis of clinical observations and biomechanical studies, based on significant clinical material. Methods. A retrospective study over a 3-year period of medical records of inpatients with mandibular fractures and their complications was carried out, in the surgical treatment of which, in the conditions of the basic clinic, the surgical algorithm developed by the authors was used. Results. Case histories of 442 patients who met the search criteria were examined. In terms of the composition of the patients included in the study group, it reflects a typical picture for this type of injury, which is typical for domestic clinical practice. The incidence of postoperative complications was 4.1% (of which accompanied by a prolongation of treatment 2% of cases). Conclusion. The results of this work showed that the real percentage of complications in patients with injuries of the lower jaw can be significantly reduced due to strict compliance with the requirements of the algorithm, which was shown by a retrospective analysis of medical records of inpatients over a three-year period, reflecting the results of treatment of a significant number of patients. The data obtained can serve as the basis for appropriate multicenter clinical trials.
Prognosis of Early Outcomes after Isolated Coronary Bypass Surgery: Results of a Single-Center Cohort Study
Authors: Golukhova Elena Z. , Keren Milena A. , Zavalikhina Tatiana V. , Bulaeva Naida I. , Marapov Damir I. , Sigaev Igor Y. , Merzlyakov Vadim Yu. , Alsibaya Mikhail D. , Volkovskaya Irina V. , Yakhiaeva Kumushdzhan B. , Sheikina Nina A.
Published: July 2023

Background. The importance of predictors of adverse outcomes after coronary bypass surgery needs to be regularly review in view of changing standards of practice. Predicting complications will help reduce current mortality and morbidity among patients who have undergone coronary bypass surgery (CABG). Aims prediction and determination of independent predictors of in-hospital mortality after CABG based on the results of preoperative examination. Methods. In a retrospective cohort single-center study, we analyzed the results of 2239 patients who underwent isolated CABG for the period from September 2018 to August 2021. The primary endpoint of the study was hospital death after CABG. Also, the frequency of: non-fatal myocardial infarction, non-fatal stroke, acute heart failure, postoperative rhythm and conduction disorders, acute renal failure, multiple organ failure, infectious complications was analyzed. Next, we searched for independent predictors and built a prognostic model for assessing the risk of death after CABG. Results. Results. Hospital mortality among patients was 1.34% (n = 30). Independent predictors of death after CABG were: ejection fraction (OR 0.91; 95% CI: 0.880.93; p 0.001), body mass index (OR 0.90; 95% CI: 0.820.99; p = 0.035), glomerular filtration rate (OR 0.97; 95% CI: 0.960.99; p = 0.005), repeated CABG (OR 9.3; 95% CI: 2.7431.24; p 0.001), critical atherosclerotic lesion of the arteries of the lower extremities (OR 4.5; 95% CI: 1.93310.268; p 0.001). The model for predicting the probability of death after CABG had high quality metrics: ROC-AUC 0.838 (95% CI: 0.7470.929; p 0.001), sensitivity 72.4%, specificity 84%. The threshold value of the logistic function P at the cut-off point, which corresponded to the highest value of the Yuden index, was 0.015. The outcome was predicted when the value of the logistic function P was higher than or equal to this value. Conclusion. We have developed a model for predicting in-hospital mortality after CABG based on independent linear predictors: left ventricular ejection fraction, body mass index, glomerular filtration rate, repeated CABG, critical atherosclerotic lesion of the main arteries of the lower extremities.
To the 75th anniversary Academician of the Russian Academy of Sciences of Yuri Konstantinovich Yanov
Authors: Reshetov Igor V. , Sergeeva Natalia V. , Serikov Alexei A.
Published: July 2023

On December 18, Lieutenant General of the medical service Yuri Konstantinovich Yanov turned 75 years old.
Influence of Charles Babbage on Supplier Selection Criteria: An Empirical Study
Authors: Chattopadhyay Shouvik
Published: July 2023

This paper deals with the emergence of supplier selection criteria in printed format. The primary aim is to associate Charles Babbage as the pioneer in putting together the supplier selection criteria in 1832. While Dickson, G W is known as the pioneer of the supplier selection process
for his work in establishing a standardised supplier selection process through a study in 1966, a comparative analysis of the criteria put forward by him with that put forward by Charles Babbage does show that we can definitely assign the tag of pioneer of the supplier selection process to
the Father of the Computer.
Consolidation behaviour of palm-oil-fuel-ash-based geopolymer treated soil
Authors: Khasib Isam Adnan , Nik Daud Nik Norsyahariati , Izadifar MohammadAli
Published: July 2023

In recent times, geopolymers have gained attention as a soil stabilisation binder due to their ability to improve the engineering properties of soil while remaining eco-friendly. This study seeks to investigate the stabilisation of soft soil using palm-oil-fuel-ash (POFA)-based geopolymers. A geopolymer was created by combining POFA with an alkaline activator solution composed of sodium hydroxide (NaOH) and sodium silicate (Na2SiO3). The mechanical and microstructural behaviours of two clayey soil types (samples S1 and S2) stabilised with four doses of the POFA-based geopolymer (G10PA, G20PA, G30PA and G40PA) were studied by conducting one-dimensional consolidation, California bearing ratio (CBR) tests, field emission scanning electron microscopy (FESEM) and X-ray diffraction (XRD). The optimum dosage found was G40PA for both soil samples. The CBR value of S1-G40PA was 1.7 times that of S1, while that of S2-G40PA was nearly 1.5 times that of S2. The void ratio of S1 was significantly reduced from 0.70 (untreated sample) to 0.56 (S2-G40PA), whereas for S2, it was decreased from 1.43 (untreated sample) to 0.43 (S2-G40PA). The microstructural analysis (FESEM) revealed that changes in material composition correlate with the consolidation behaviour, with the geopolymer gel-binding effect enhancing the mechanical properties of stabilised soils.
ON HYDROCARBON VAPOR UTILIZATION WHILE BITUMEN PRODUCTION
Authors: Vyakherev Nikita S. , Sidorov Georgy M. , Zaykina Ekaterina Y.
Published: July 2023

As it is known, bitumen producers face the problem of utilization of hydrocarbon vapors formed during the oxidation process. At type 19/3 installations, petroleum products and vaporous products condensed in a scrubber are pumped out in large quantities to the ELOU units to be involved in the process of re-refining or burned in afterburning furnaces together with the gas part. The existing methods of hydrocarbon vapor utilization are not economically efficient and harmful to the environment. This article describes a method of utilization of hydrocarbon vapors involving them in the of bitumen production process using a column-type scrubber as an oxidation reactor, and blowing itself as a plasticizing agent. A laboratory experiment was also carried out on a batch bitumen production unit to assess the possibility of using this method for raw materials obtained from a mixture of Arlan and West Siberian oils. The results obtained during the experiment showed that this method is effective for road bitumen production according to State Standard 33133-2014, and is also more environmentally friendly than the hydrocarbon vapors utilization method used at refineries at the moment.
FIELD EXPERIENCE OF DOWNHOLE EQUIPMENT OPERATION IN HYDROGEN SULFIDE-CONTAINING ENVIRONMENTS
Authors: Lunin Dmitry A. , Minchenko Dmitry A. , Noskov Andrey B. , Klyushin Igor G. , Bikaev Ilnar I. , Maltsev Dmitry I. , Galiev Nail A. , Markin Andrey N. , Tkacheva Valeriya E. , Valekzhanin Ilya V.
Published: July 2023

The article describes the results of operation of downhole equipment in hydrogen sulfide-containing media in relation to local and corrosion-mechanical failures. Useful life (without anti-corrosion protection) for most common manganese steel tubing before the appearance of through fracture was shown. The minimum concentrations of H2S and CO2 in the water phase for wellhead sample are shown when determining the degree of corrosivity of well media and types of corrosion depending on their concentration, in relation to carbon and low-alloy steels. The corrosion-mechanical destructions the downhole equipment were visualized according to GOST 53679. The necessity of taking into account the tendency of stainless steel grade 40Х13 (foreign analogue in the USA is AISI 420) of intersection splined couplings and shafts of an electric centrifugal pump unit made of steel grade 05Х16Н4Д2Б (foreign analogue is not defined) to hydrogen embrittlement as a result of exposure to acidic compositions (12–15 % HCl), used in technological operations, is shown. Practical solutions are proposed for tubing resistant to local and corrosion-mechanical failures (by steel grades and strength groups) based on the proposals of a domestic manufacturer. Two main factors are shown that reduce the service life of tubing and couplings to them to one year. Four polymorphic forms of iron sulfide (the main products of hydrogen sulfide (H2S-) and mixed (CO2 + H2S) corrosion), the conditions for their formation and the maximum rate of local corrosion, up to a through ulcer, under sulfide deposits, were identified. The statistics of tubing by steel grades and the percentage of their use in the fields operated by the Company are shown.
Autoevaluación y formación del ser en la universidad: revisión narrativa
Authors: Kambourova Miglena , Galindo Cárdenas Leonor , Villa Vélez Lilliana
Published: July 2023

En este artículo se presenta una revisión bibliográfica derivada de la investigación “La autoevaluación del aprendizaje como parte de la formación integral de los estudiantes en los pregrados de la Facultad de Medicina de la Universidad de Antioquia”. Esta revisión se centra en la autoevaluación del aprendizaje, la formación integral y la relación entre ellas; su objetivo es presentar los avances y las tendencias de discusión sobre la temática a partir de la sistematización y la integración de referentes teóricos y resultados de diferentes estudios. De esta forma, se evidencia una evolución en la comprensión de los conceptos indagados y en las perspectivas de las investigaciones, en las cuales la autoevaluación es esencial, como parte del enfoque de la evaluación para el aprendizaje.
Reflexos da COVID-19 na saúde mental de estudantes universitários
Authors: Gonçalves Sónia P. , Vieira dos Santos Joana , Silva Isabel
Published: July 2023

Face à situação pandémica, as universidades atravessaram um conjunto de desafios, nomeadamente, a mudança do ensino “face a face” para aulas online. O presente estudo visa contribuir para a compreensão da situação de confinamento em estudantes universitários portugueses, através da análise dos níveis de stress percebido, sintomas de ansiedade e depressão. Participaram no estudo 694 estudantes do ensino superior português. Os resultados denotam sintomas moderados a severos de perturbação ansiosa, bem como o contributo explicativo de variáveis sociodemográficas, académicas e de vivência da pandemia. De destacar por um lado, o papel protetor da satisfação com o acompanhamento e supervisão por parte dos docentes e de ter momentos “isolados” para estudar. Por outro lado, os resultados revelam que a preocupação com a pandemia e com o seu impacto no percurso educacional são fatores de risco. Este estudo possibilita destacar pontos chaves de foco na prevenção de sintomatologia de ansiedade.
Surgical options in melanoma metastasis in regional lymph nodes
Authors: Bukharov A. V. , Erin D. A. , Derzhavin V. A. , Yadrina A. V. , Elkhov D. O.
Published: July 2023

This review presents an analysis of treatment outcomes for patients with metastases of cutaneous melanoma into the regional lymph nodes. Types of surgical interventions currently used in oncological surgery for this pathology are considered, as well as the trends of their future practical application. The results of sentinel lymph node biopsy and regional lymph node dissection in patients with primary tumors with varying thickness and the effect of surgical interventions on treatment effectiveness are presented.
Programmed death-ligand 1 and p53 as a biomarker in predicting oropharyngeal squamous cell carcinoma
Authors: Polatova D. Sh. , Madaminov A. Yu. , Savkin A. V. , Kakhkharov A. Zh. , Botiralieva G. K. , Madaliev A. A. , Yuldashkhodzhaeva N. B. , Khuzhaev Sh. K.
Published: July 2023

Introduction. Currently, the pathogenetic role of the human papillomavirus (HPV) in carcinogenesis is well studied, that most cases of oropharyngeal squamous cell carcinoma are associated with the persistence of this infection. In addition to HPV infection, the involvement of programmed death-ligand 1 (PD-L1) and p53 proteins in the initiation and progression of oropharyngeal squamous cell carcinoma provides their formation as additional biomarkers in predicting the disease.

Aim. To study the prognostic role of PD-L1 and p53 expression in oropharyngeal squamous cell carcinoma depending on HPV status.

Materials and methods. The study included 62 patients with oropharyngeal squamous cell carcinoma T1–4N0–3M0 (Tumor, Nodus and Metastasis, (TNM), 7th edition) treated in 2015–2020 at the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology and in the Tashkent and Samarkand city branches. All patients underwent immunohistochemical analysis for the presence of p16INK4a, PD-L1 and p53 protein expression in formalin-fixed and paraffin-embedded tumor tissue samples.

Results. Based on the results of the assessment, it was found that positive HPV status, low and medium levels of PD-L1 expression and positive regulation of wild-type p53 are associated with favorable outcomes in patients with oropharyngeal squamous cell carcinoma. Negative HPV status, high and very high levels of PD-L1 expression, loss of wild type p53 function with upregulation of p53 mutant type leads to worse disease outcomes.

Conclusion. Thus, the assessment of the expression of the onco-suppressor protein p53 helps to determine the biology of cancer cells in patients with oropharyngeal squamous cell carcinoma and suggest sensitivity to ongoing therapy, and by studying the regulation of the PD-L1 protein, antitumor immune regulation can be suggested in these patients.
Juan Simón Gutiérrez, intérprete de la persuasión murillesca
Authors: Muñoz Nieto Enrique
Published: July 2023

El Museo del Greco de Toledo cuenta entre sus fondos artísticos con una pintura que representa a Santa Bárbara, de escuela sevillana. Reconocida por María Elena Gómez-Moreno como perteneciente al círculo de Murillo, el conocimiento actual sobre el panorama pictórico sevillano relativo a discípulos, sucesores e imitadores del maestro permite adscribir la obra a Juan Simón Gutiérrez (1634-1718). Dicha atribución sirve como pretexto realizar un análisis sobre la representación de la santidad femenina en la pintura barroca sevillana, principalmente dentro del contexto murillesco.
La arquitectura medieval leonesa en el foco de interés de los arquitectos catalanes a finales del siglo XIX y principios del XX. Los casos de Luís Domènech Montaner y Rafael Masó Valentí
Authors: Jimeno Guerra Vanessa
Published: July 2023

El presente trabajo se centra en la importancia que ostentó la arquitectura medieval a lo largo del siglo XIX y los comienzos del XX, no sólo en el pensamiento de la época sino también en la formación de los arquitectos del momento.

Destacados monumentos como la Catedral de León y la Real Colegiata de San Isidoro de la misma ciudad fueron objeto de estudio y consideración por parte de figuras tan notables como Luís Domènech Montaner y Rafael Masó Valentí. Las anotaciones y reflexiones que sobre estos realizaron, así como las imágenes que captaron en forma de fotografías y dibujos, inéditas hasta el presente estudio, son una importante fuente de información sobre el estado de estos monumentos en aquel momento.
The paradoxical moderating effects of metacognition in the relationships between self-esteem, depressive symptoms, and quality of life in anorexia and bulimia
Authors: Springfield Cassi R. , Bonfils Kelsey A. , Chernov Nikita V. , Moiseeva Tatyana V. , Sozinova Marta V. , Dmitryeva Nadezhda G. , Lysaker Paul H. , Karpenko Olga A. , Kostyuk George P.
Published: July 2023

BACKGROUND: Self-esteem and depressive symptoms contribute to a lower quality of life in people suffering from eating disorders. However, limited research has examined whether other factors may affect how these variables influence one another over time. Metacognition is a previously unexplored determinant that may impact the relationships between self-esteem, depressive symptoms, and quality of life in instances of eating disorders.
AIM: This study sought to examine metacognitive self-reflectivity and mastery as moderators of the relationships between self-esteem, depressive symptoms, and quality of life and to determine if these relationships are different in people with anorexia compared with people with bulimia.
METHODS: Participants with anorexia (n=40) and bulimia (n=40) were recruited from outpatient clinics. The participants were assessed on their metacognitive ability and self-reported on measures to assess their depressive symptoms, self-esteem, and quality of life.
RESULTS: The results indicate that metacognitive self-reflectivity moderates the relationship between self-esteem, depressive symptoms, and quality of life in people with anorexia such that when self-reflectivity is high, lower self-esteem and higher depressive symptoms are associated with a lower quality of life. These relationships did not appear to be significant when self-reflectivity was low. In contrast, in the anorexia and bulimia groups, metacognitive mastery appeared to moderate the relationships between self-esteem, depressive symptoms, and quality of life such that when mastery was low, lower self-esteem and higher depressive symptoms were associated with a lower quality of life. These relationships did not appear significant when mastery was high.
CONCLUSION: Metacognitive self-reflectivity and mastery seem to play paradoxical moderating roles in the relationships between self-esteem, depressive symptoms, and quality of life in people with anorexia and bulimia. These findings pave the way toward further research and have important clinical implications.
The Construct of Strict Liability in Criminal Law of England and Wales in the Context of Polish Legal Regulations on the Subjective Element in the Structure of a Prohibited Act
Authors: Lewna Andrzej
Published: July 2023

The construction of strict liability has been for years one of the most controversial concepts in the field of substantive criminal law in common law countries. While the very idea of basing the liability of an individual of a repressive nature on a regime based on strictly objective assessments seems to stand in opposition to the principles of criminal law that are fundamental to Western systems, such as the individualization of liability and the principle of guilt, at the same time, the use of the construct discussed may bring about considerable instrumental benefits, especially with regard to the protective function of criminal law. The article discusses the concept of strict criminal liability as developed in the system of England and Wales and presents the position that this concept occupies in relation to the classic for Anglo-Saxon countries, a two-element approach to the structure of a prohibited act, based on the correspondence of both objective and subjective components, and then transfers the considered problems onto the Polish criminal law plane in order to analyse the possibility of adapting an analogous construct in the statutory regulation of the subjective side of a prohibited act. In addition, the article presents the thesis that the advantages of strict liability may support the modification of the national approach towards a partial resignation from the requirements of the presence of a specific subjective element in the psyche of the perpetrator of a prohibited act in relation to all its objective features.
Big Data Profiling and Predictive Analytics from the Perspective of GDPR
Authors: Siwicki Maciej
Published: July 2023

The text analyses the normative regulations adopted by the Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data (GDPR) in order to answer the question whether the said regulations properly balance the interests of both entities that use predictive analytics and profiling in their economic activity, and of persons whose data they process. As this type of processing is based on big data, the proper analysis of this issue had to begin with determining which types of data processed in such sets can be considered personal information and in what conditions they can be treated as such. Based on these findings, the study analyzed the duties imposed by the GDPR on entities processing personal data in situations when such information has been obtained from big data. This in turn made it possible to assess the adopted normative regulations as well as point to the possible solutions and development paths.
Promoting Social Economy as an Instrument for Institutional Change: The Case of Bulgaria
Authors: Vutsova Albena , Yalamov Todor , Arabadzhieva Martina
Published: July 2023

The following paper presents three related narratives. The first one looks at the dynamics of definitions of social economy and social enterprises. The second presents the Bulgarian perspective on social enterprises from different data sources with a focus on particular regulatory gaps, which impede the development of specific social enterprises in Bulgaria, called chitalishte. They have the longest and most steady tradition in the country among the not-for-profit organizations. The third narrative presents a story of non-profit social enterprises as agents of institutional change. The examples used in the paper arose in different time periods, have different specifics, but all emphasize the importance of the economic and social environment for the degree of sway on the institutional profile of chitalishta. The specific forms of Bulgarian social entities were studied in order to demonstrate their potential for institutional changes, expected level of impact, and compliance with coherent policies. Some regulatory deficiencies that narrow the scope of their action were also analyzed.
Opiniones de los dirigentes políticos sobre los problemas del agua y sus implicaciones en la enseñanza de la cultura del agua
Authors: Ramírez Segado Alejandra , Rodríguez Serrano María , Benarroch Benarroch Alicia
Published: July 2023

En lo que respecta a los recursos hídricos, desde mediados del siglo XX, se han desarrollado políticas de gestión basadas en estrategias de oferta, llamadas así porque están encaminadas a satisfacer la demanda creciente de agua. En cambio, la Nueva Cultura del Agua reivindica una gestión sostenible del agua y de los recursos hídricos. En este trabajo, se hace frente al reto de conocer qué tendencias en la toma de decisiones relacionadas con el agua tienen diez dirigentes políticos y responsables de la gestión del agua en la Ciudad Autónoma de Melilla, con el objetivo de generar conocimiento para la toma de decisiones acerca de cómo llevar la problemática del agua al aula. Para ello, se ha utilizado, como técnica de recogida de información, la entrevista. Los resultados indican que los entrevistados tienen amplios conocimientos sobre el agua, su problemática y su gestión. Se concluye que las alternativas de respuesta recabadas en esta investigación pueden ser útiles para llevar al aula esta temática como conflicto socio-científico dirigido a despertar una actitud crítica y una alfabetización científica.
Emociones y autoeficacia del alumnado de Educación Secundaria ante contenidos de Biología y Geología
Authors: Muñoz Expósito José Luis , Esteban Gallego María Rocío , Dávila Acedo María Antonia , Marcos Merino José María
Published: July 2023

La investigación en didáctica de las ciencias ha mostrado durante los últimos años un interés creciente en el estudio de los aspectos afectivos (como las emociones o la autoeficacia) de alumnos y profesores hacia la enseñanza y el aprendizaje de las ciencias. El objetivo de esta investigación es diagnosticar las emociones y la autoeficacia de una muestra de 764 alumnos, de 1º, 3º y 4º de Educación Secundaria, ante los contenidos de Biología y Geología, asimismo analizar las causas de esas emociones. Se ha encontrado que los participantes sienten más emociones positivas que negativas, así como alta autoeficacia, en la práctica totalidad de los contenidos. Sin embargo, los ítems de Geología obtienen mayor promedio de emociones negativas y menor de positivas y autoeficacia que los de Biología. Respecto a las causas de las emociones, se aducen tanto afectivas como cognitivas; apuntando a actitudes en el alumno o en el profesor, o a la metodología.
La marca literario en los diccionarios españoles de la segunda mitad del siglo XX
Authors: Ruiz Martínez Ana María
Published: July 2023

En esta investigación examinaremos la marca literario en los diccionarios españoles de la segunda mitad del siglo XX (desde Gili Gaya, 1973 [1945] hasta Sánchez Pérez, 2001), así como el rigor y la claridad con que se utiliza. Con relación a la metodología, hemos revisado la marca en las monografías metalexicográficas de referencia que la mencionan y en los diccionarios en los que es utilizada en las últimas décadas. Gracias a los resultados obtenidos, podremos esclarecer cómo está asentada la marca literario en la lexicografía española reciente, cómo se presenta en los diccionarios que la utilizan y si convive con otras marcas o mecanismos empleados por la lexicografía que transmiten alguno de sus contenidos. Estos resultados nos permitirán alcanzar algunas conclusiones de carácter general sobre la marcación lexicográfica.
Formulation and evaluation of herbal hand wash using neem and aloevera extract
Authors: Tikariya Komal , Gawshinde Arpit , Dabeer Ali , Mishra Sonu , Atneriya Umesh K. , Solanki Dharmendra
Published: July 2023

The herbal cosmetics are natural and free from all the harmful synthetic chemicals which generally may turn out to be lethal to the skin, the natural ingredient used assures no side effect one can applied them any time. So, herbal cosmetic are more referable as compared to synthetics one.

The purpose of the present work is to formulate and evaluated herbal hand wash using natural ingredients to promote the personal hygiene. The formulated hand wash was evaluated for different parameters like pH, colors, foaming efficiency, viscosity and stability.

The herbal hand wash formulated using neem extract for antibacterial property, aloevera juice for soothing property, glycerine for moisturization, sodium lauryl sulphate as a surfactant, carbopol 934 as a jellying agent, rose oil for fragrance and distilled water, the hand wash is prepared and evaluated then the result was documented.

5 People were asked for acceptability of fragrance and their opinion was taken. The fragrance was found to be good as compared to reference hand wash.

: The hand wash was found to be light green aromatic and homogeneous with rosy fragrance. pH was 6.0 which is similar to the skin pH. The hand wash was found to be stable in all evaluation parameters with good cleaning property.
Medication error in geriatric population of an urban area and its relation with different factors influencing medication error
Authors: Iqbal Rashid , Kumar Ratan , Barnwal Rajan
Published: July 2023

Medication errors have been a matter of concern since the time we started using medicines. The frequency of these errors is influenced by a number of factors few of them were pretty obvious and few surprising. Keeping this in mind this research was designed and carried out in geriatric population of an urban area. We tried to evaluate the role of various factors which influence medication error in geriatric population.

1-Primary objective was to estimate the frequency of medication error. 2-Secondary objective was to find out relation of different factors related to medication error.

This is a cross sectional study which aims to estimate the frequency of medication error in 250 patients of geriatric age group (Age More Than 65 Years) residing in an urban area and factors related to medication error

For this a questionnaire was prepared which had questions related to demographic details and few questions focused on knowing the factors that could have an influence on medication error. These factors were taken into consideration as per the previous studies which were done on medication error.

It was found that more than 80% of patients thought that medication errors are only those incidents where they use a medication other than what was prescribed to them hence Patients were properly explained what medication error actually is e.g. they were told that even if they take the correct mediation in wrong dose, frequency or duration it accounts for medication error and after this they started recalling incidents when they have faced these errors. There responses were entered into these questionnaire/case record forms which were later analysed.

The data was entered in MS excel and analysed using Epi Info software. The quantitative variables were analysed as frequency. Association between variables was analysed using chi square test. P value <0.05 was considered as significant .

The incidence of medication error was found to be 53% and its frequency was higher in patients with greater number of medications, increasing number of chronic health conditions , while it was lower in patients with higher educational status ,those belonging to lower age groups and if doctor or pharmacist explained the medications to them. surprisingly its frequency was low in patients who could just identify their medication with their health condition.

It was concluded that medication errors are common health related issue in patients of geriatric age group and a number of factors can influence its incidence. If these factors are properly addressed it will have a considerable impact on the morbidity and mortality associated with this problem.
Delineating the grey areas in radiodiagnosis-Radiomics a new way forward Radiomics- A virtual biopsy
Authors: Sanjay Gayathri , Shreedhara Lekha , Guttal Kruthika S , Nandimath Kirty , Burde Krishna
Published: July 2023

Omics are the branches of science which constitute the various affiliates of biology. It determines the structure, function and dynamics of organisms through collective characterization and quantification of biological molecules. The diagnostic imaging modalities have peaked in their advancements, leading to escalated complexity and volume of database. This has ushered the foundation of a novel approach to imaging diagnosis called radiomics. Radiomics refers to the accentuation and procurement of ambiguous data from medical imaging and has been applied within oncology to enhance diagnosis and prognostication, aiding in clinical decision, with the aim of delivering precision medicine. The chief application of radiomics is in oncology to augment diagnosis and prognosis, thereby improving clinical decision. Consequently, the success rates for delivering precision medicine is higher as it facilitates the procurement and accentuation of ambiguous data from rradiographs. Radiologists as well as data and imaging scientists represent an integral part of the interdisciplinary workflow of radiomics. It involves a comprehensive process of step by step tumour segmentation, image pre-processing, feature extraction, analysis, model development, and validation. By this paramount potentiality, it serves as a definitive solution for both clinical and research purposes. This paper highlights the role of radiomics in defining, standardization, and cultivating vast databases accessible to clinicians. This will empower them to tap into every particular case, eventually creating a link among patients having comparable profiles for treatments or clinical trials all over the world.
Conservative approach in the management of large periapical lesion in a long standing trauma case: A case report
Authors: Hamid Saima , Malik Azhar , Kumar Ajay , Anjum Shamim , Dhani Rachna , Hamid Tahira
Published: July 2023

Pulpal and periradicular pathology is the common sequel following trauma to the teeth severe enough to cause displacement of tooth resulting in necrosis of pulp as a result of severing of neurovascular supply near apical constriction. This case report evidenced a conservative non-surgical endodontic management of a large periapical lesion in a 19-year-old young male induced due to traumatic injury to the face.
Mors sceptra ligonibus aequat. El ritual de la muerte en la Galicia de los siglos XVII y XVIII
Authors: González Lopo Domingo L.
Published: July 2023

RESUMENEn este artículo analizaremos, tomando como referencia la documentación testamentaria, el ritual funerario en la ciudad de Compostela, así como su evolución entre finales del siglo xviii y el mismo periodo de la siguiente centuria, prestando atención a los cambios y las causas que las provocan, así como a sus consecuencias. Palabras clave: ritual funerario, velatorio, entierro, órdenes religiosas, cofradíasTopónimos: GaliciaPeriodo: siglos xvii y xviii ABSTRACTIn this article we will analyze, taking testamentary documentation as a reference, the funeral ritual in the city of Compostela; as well as its evolution during the end of the 17th and 18th centuries, paying attention to the changes and the causes that provoked them, as well as their consequences. Keywords: funeral ritual, wake, burial, religious orders, brotherhoods Place names: GaliciaPeriod: 17th and 18th centuries REFERENCIASAres Legaspi, A., “Catálogo dos documentos do Libro de facenda da I confraría dos cregos do coro da igrexa de Santiago de Compostela”, Annuarium Sancti Icobi, 7 (2018), pp. 165-227.Barreiro Mallón, B., “Los gremios compostelanos. Algunos datos y reflexiones”, Liceo Franciscano, 85-87 (1976), pp. 119-149. De Lara Ródenas, M. J., La muerte barroca. Ceremonia y sociabilidad funeral en Huelva durante el siglo xvii. Universidad de Huelva, Huelva, 1999.Eiras Roel, A., Estudios sobre agricultura y población en la España Moderna. Santiago de Compostela, Tórculo, 1990.González Lopo, D. L., Los comportamientos religiosos en la Galicia del Barroco. Santiago de Compostela, Xunta de Galicia, 2002.—“Balance y perspectivas de los estudios sobre la VOT Franciscana en Galicia (siglos xvii-xix)”, en El Franciscanismo en la Península Ibérica. Balance y perspectivas. Barcelona, GBG Editora, pp. 567-583.—“¿Cómo se construye la historia de un santo? La imagen del santo y su evolución a través de los siglos: el ejemplo de S. Rosendo de Celanova”, Lusitania Sacra, 28 (2013), pp. 21-48.López López, R., Comportamientos religiosos en Asturias durante el Antiguo Régimen. Oviedo, Silvio Cañada, 1989.Martínez Gil, F., Muerte y sociedad en la España de los Austrias, Madrid, Siglo XXI, 1993.—Toledo y la crisis de Castilla, 1677-1686. NUPREDSA, Talavera, 1987.Peñafiel Ramón, A., Testamento y buena muerte. (Un estudio de mentalidades en la Murcia del siglo xviii. Murcia, Academia Alfonso X el Sabio, 1987.
Contributions to the biodiversity of echinoderms (Echinodermata) in the Department of Atlántico, Caribbean Sea, Colombia
Authors: Contreras-Rueda Yully F. , Gracia-Clavijo María Adriana , Romero-Paz Jairo E.
Published: July 2023

Echinoderms are a marine invertebrate group with important ecological functions in the ocean; they are the source of bioactive compounds, and some species are important for fisheries and aquaculture. Their study in the Colombian Caribbean has focused on taxonomic and ecological aspects and they are a well-documented group of invertebrates. However, small-scale studies of the group are required given the geomorphological and oceanographic diversity along the entire Colombian coastline. The Magdalena River runoff strongly influences the coastal ecosystems of the Department of Atlántico, which has the shortest continental shoreline with only 72 km. The benthic fauna in its surroundings is the biotic component receiving the influence of this river directly, but it has not been the object of deep taxonomic and ecological studies. Field echinoderm surveys were conducted at several sites from 2004 to 2019. Observations and direct collections were carried out from 0 to 5 m depth. We identified four classes, seven orders, eight families, ten genera, and 16 species. Thirteen of these species were first records for Atlántico: Luidia senegalensis, Astropecten articulatus, Amphiodia riisei, Amphiodia trychna, Echinometra lucunter lucunter, Encope michelini, Leodia sexiesperforata, Mellita quinquiesperforata, Isostichopus badionotus, Isostichopus sp., Holothuria grisea, Holothuria glaberrima, and Holothuria princeps. The most frequently observed species were M. quinquiesperforata and H. glaberrima. We provide the local geographic distribution, illustrations, and remarks on each species. This study attempts to close gaps regarding the knowledge of the distribution of marine invertebrates in the Colombian Caribbean Sea.
Sinopsis del género Micropholis (Sapotacea) en Colombia y clave para la identificación de sus especies
Authors: Piñeros-U. Liseth Paola , Cortés-B. Rocío , Richardson James E.
Published: July 2023

Se presenta la sinopsis del género Micropholis (Sapotaceae) en Colombia. Se incluye la descripción del género, una clave de identificación de las especies, la descripción de cada una, su distribución geográfica y su fenología. La sinopsis se hizo con base en el estudio de ejemplares de las colecciones de siete herbarios, la observación de algunas especies en su hábitat natural y el estudio de imágenes digitales de los especímenes tipo. Aunque en la última revisión taxonómica se registraron cinco especies en Colombia, el catálogo de plantas y líquenes sugiere la presencia de 18 especies en el país y colecciones posteriores han elevado este número a 19, las cuales se encuentran distribuidas especialmente en los bosques húmedos de tierras bajas, sobre todo en la Amazonía y en el occidente del país. M. guyanensis y M. venulosa son las especies más ampliamente distribuidas en el país.
Evaluación computacional de las interacciones de compuestos naturales y el dominio unión al ARN de las nucleolinas utilizando acoplamiento molecular y simulaciones de dinámica molecular
Authors: Gayozo-Melgarejo Elvio , Rojas-Aguadé Laura
Published: July 2023

Varios estudios proponen la nucleolina como un blanco alternativo para la búsqueda y el diseño de nuevas terapias antitumorales o anticancerígenas. El objetivo de este estudio fue evaluar compuestos con potenciales afinidades de unión al ARN de las nucleolinas mediante herramientas bioinformáticas. Se evaluaron diez compuestos de los cuales tres moléculas (ácido betulínico, triptolide y berberina) presentaron afinidades de interacción con el dominio de unión al ARN (RNA binding domain, RBD), exhibiendo valores de energía de unión significativamente favorables (p<0,05) y una constante de disociación calculada (Kd calc) entre 0,14 y 0,91 μM. Las simulaciones de dinámica molecular evidenciaron que únicamente el complejo nucleolina-berberina tuvo estabilidad de interacción y energía libre de unión favorable en el tiempo simulado. Los residuos involucrados en la formación del complejo eran aminoácidos que cumplen funciones importantes en el sitio activo. Los hallazgos sugieren que, entre los compuestos evaluados, la berberina tuvo resultados favorables como potencial inhibidor de las actividades de la nucleolina, específicamente del dominio RBD.
La presencia de Sloanea multinervis (Elaeocarpaceae) en Colombia
Authors: Palacios Duque Leonardo
Published: July 2023

Se documenta en Colombia el primer registro de Sloanea multinervis J.E. Guevara, D. Fernández y W. Palacios, especie que sólo se conocía por su protólogo, y cuya presencia se restringía a la Amazonía ecuatoriana.
El Grupo de Astrofísica Solar (GoSA) del Observatorio Astronómico Nacional de Colombia: 10 años indagando sobre la ciencia del Sol
Authors: Vargas-Domínguez Santiago , Calvo-Mozo Benjamín , Martínez Oliveros Juan Carlos , Buitrago-Casas Juan Camilo
Published: July 2023

El Grupo de Astrofísica Solar (GoSA) del Observatorio  Astronómico Nacional de Colombia es un grupo de investigación que se dedica al estudio de la astrofísica solar. El grupo cumplió su décimo aniversario en el 2022, período durante el cual ha contribuido significativamente a la investigación en astrofísica solar, la formación de estudiantes y la apropiación social de la ciencia en Colombia. Esta reseña abarca desde los aspectos relacionados con la investigación en la física del Sol, resaltando los principales logros del GoSA desde su conformación, hasta las perspectivas en los proyectos futuros para seguir profundizando en el entendimiento del Sol y los desafíos de este campo de investigación.
Contextualizando os conceitos de cinética química em uma turma de jovens e adultos
Authors: Figueiredo Alessandra Marcone Tavares Alves de , Lima Luís Victor Dos Santos , Silva Amanda Cecília Da , Souza Niely Silva de , Araújo Rafael De Carvalho
Published: July 2023

O presente trabalho foi realizado em uma escola pública da rede federal de ensino situada em João Pessoa, numa turma de jovens e adultos do Curso Técnico Integrado em Eventos. Objetivando um aprendizado mais interativo e contextualizado, conceitos unificadores da disciplina Química foram trabalhados dentro de uma perspectiva que favoreceu a construção do saber do público participante. Para tanto, empregou-se a experimentação, que se mostrou ser uma atividade de grande valia, pois, ao observar as reações que estavam ocorrendo, os alunos se envolveram, fazendo reflexões com o que eles encontravam em seu dia a dia. Os resultados apontaram para um arrefecimento do mito negativo existente acerca desta ciência, ao proporcionar, aos discentes envolvidos, um transitar entre o saber popular e o saber científico.
Crisoberilo: primeira ocorrência na Província Pegmatítica da Borborema, NE do Brasil
Authors: Soares Dwight Rodrigues , Beurlen Hartmut , Ferreira Ana Cláudia Mousinho , Gonzaga Francisco de Assis Da Silveira
Published: July 2023

Este trabalho descreve a primeira ocorrência de crisoberilo em pegmatitos na Província Pegmatítica da Borborema (PPB). O pegmatito hospedeiro do crisoberilo é o Roncadeira, localizado a 4 km WNW da cidade de Nova Palmeira, Paraíba. É um pegmatito de elementos raros, classificado como: tipo berilo, subtipo berilo-columbita-fosfato, pouco zonado, constituído entre outros de albita, muscovita, quartzo, cassiterita, gahnita e zinconigerita, encaixado discordantemente em biotita-granada-xisto da Formação Seridó. O crisoberilo ocorre sob a forma de cristais tabulares, de cor verde amarelado pálido, com geminação pseudohexagonal típica e dimensões de 15 × 4 mm. A composição química do crisoberilo, calculada a partir de suas composições catiônicas, é expressa por Be(Al1,795Fe2+0,024Si0,001)O4.
Comportamento do sistema de aterramento de LDs 69 kV com estruturas de concreto sob descargas atmosféricas
Authors: Dália Antonio Dos Santos , Pamplona Franklin Martins , Oliveira José Tavares de
Published: July 2023

Este trabalho analisa o comportamento do sistema de aterramento de Linhas de Distribuição de 69kV com estruturas de concreto dotadas de cabo para-raios quando submetidas a descargas atmosféricas. Neste estudo, foram modelados com a utilização do software ATPDraw a estrutura majoritariamente presente nas Linhas de Distribuição, o sistema de aterramento e a magnitude da descarga atmosférica, e foram analisados os resultados de simulação com relação à resistividade e aos comprimentos do cabo de aterramento.