bluuebunny/crossref_metadata_2025 huggingface dataset:
MORPHOLOGICAL AND FUNCTIONAL FEATURES AND THE LEVEL OF PHYSICAL DEVELOPMENT OF GIRLS OF YOUTHFUL AGE OF THE REPUBLIC MORDOVIA
Authors: Mishechkin Maksim M. , Chairkin Ivan N. , Selyakin Sergey P. , Yurtaykina Mariya N. , Rybakov Aleksey G. , Parshin Aleksandr A. , Kondyurova Evgeniya V. , Chernova Anna A.
Published: April 2021

Students belong to a group of high health risks, since during this period of development, young people are under the influence of the inevitable processes of active physiological restructuring of the body and intensive socialization of the individual. The purpose of the study is the anthropometric indicators and indices of physical development of 1648 girls aged 17-21 of the Republic Mordovia. Anthropometric measurements included the determination of the following parameters: body weight, standing and sitting body length, circumference of the chest, shoulder, forearm, wrist, thigh, abdomen, buttocks, lower leg, ankles. The comprehensive research program was designed in such a way that it was possible to calculate body surface areas, weight and height values, body strength indices and body proportionality indices. It was found that in the studied population, girls have a wide face, a narrow long nose, and a medium-sized skull. The majority of the population is characterized by the absence of excess body weight. Girls have a normosthenic type of constitution, have an average level of physical development, an average level of body density. Among female students, a mesomorphic type of physique is common with proportional body development, a normal proportion of the bone component and a slightly increased proportion of fat and muscle components. The inversion and dysplasia of sexual dimorphism revealed in the course of the study may be a response of a more labile female body to the negative influences of social and environmental factors.
NEURONAL-GLIAL MEMBRANE CONTACTS DURING PESSIMAL ELECTRICAL STIMULATION
Authors: Sotnikov Oleg S. , Sergeeva Svetlana S. , Vasyagina Tat'yana I.
Published: April 2021

After the creation of a method for obtaining inter-neuronal gap junctions in a nervous system devoid of glia, it is expedient to reproduce gap neuronal-glial contacts on a model that also contains hybrid neuronal-glial gap junctions, which, as you know, are functionally fundamentally different from inter-neuronal contacts. The experiments were carried out on the truncus sympathicus ganglia of laboratory rats using pessimal electrical stimulation and transmission electron microscopy. Electrical activation of ganglia with a frequency of up to 100 Hz revealed local and widespread variants of various neuronal-glial connections (contacts, bridges), fringed with peri-membrane filamentous proteins. They had a blurred veil that masked two-layer neuro-membranes. Some of the contacts resembled slit or dense 5-layer structures without a visible inter-neuronal slit, but with an extreme decrease in the thickness of the contact slit. The main result of the experiments was the formation, in addition to slotted, multiple septate (ladder) contacts. Relatively independent aggregates of the electron-dense substance of the septa were located inside the intercellular gaps, crossing both adjacent membranes, and, possibly, permeate of them. Near-membrane, poorly outlined pyramid-like protein cones associated with both cell membranes were also formed. Such membranes appeared to be dotted-dashed, that is, not continuous. A significant number of septic contact membranes had endocytic invaginations (invaginations) facing neuroplasm with pyramid-like marginal projections. All reactive altered structures that have arisen de novo are considered by the authors as developed under the influence of frequency electrical stimulation of denaturation and aggregation of intrinsic and perimembrane proteins.
Artefatos de leitura
Authors:   Universidade Estadual de Campinas, Dias Cristiane Pereira Costa , Costa Greciely Cristina da , Barbai Marcos Aurelio ,   Universidade Estadual de Campinas,   Universidade Estadual de Campinas, Laboratório de Estudos Urbanos
Published: April 2021

A produção deste livro privilegia, em seu escopo, a discussão de diferentes artefatos de leitura, bem como de questões sobre o método, práticas de análise e dispositivo de leitura e interpretação. Para tanto, foram fundamentais as questões levantadas no X Encontro Internacional Saber Urbano e Linguagem (EIS)1 de 2019, promovido pelo Laboratório de Estudos Urbanos (Labeurb), no qual se discutiu a temática dos Artefatos de Leitura, em torno da problemática e dos desafios do urbano, com vistas à compreensão do lugar da leitura no processo de produção de conhecimento, alicerçando-se, em especial, em um estudo de Orlandi (2003), que parte do pressuposto de que o artefato incide na práxis científica, faz parte dela enquanto um “artefato teoricamente fabricado e que se apresenta como uma técnica sustentada em um método” (ORLANDI, 2003, p. 13). Partindo-se da premissa de que a construção de artefatos faz parte do processo da produção científica, o evento promoveu a realização de um debate dedicado a interrogar, da perspectiva da linguagem, o processo de produção de conhecimento de modo a dar lugar a diferentes formas de compreensão do objeto da pesquisa situando o lugar da leitura neste processo. Além disso, buscou-se refletir sobre as discursividades do utilitarismo da ciência em circulação na sociedade atual levantando como questão a posição que o conhecimento ocupa nesta conjuntura histórica e política, sobretudo, no que diz respeito às ciências humanas, especialmente às ciências da linguagem. Boa parte desta discussão se corporifica neste livro.
O processo de inclusão de alunos com deficiência
Authors: Souza Francieli Machado de , Sanfelice Gustavo Roese , Zucchetti Dinora Tereza
Published: April 2021

Este artigo tem como objetivo analisar as ações adotadas para o processo de inclusão dos alunos com deficiência de uma universidade do Rio Grande do Sul. Para tanto, caracterizou-se como uma metodologia qualitativa, descritiva e interpretativa, tendo como amostra 5 colaboradoras, sendo 4 do Núcleo de Apoio à Inclusão e Acessibilidade (NAIA) e 1 do Núcleo de Apoio ao Estudante (NAE). Foi utilizado como instrumento de coleta de dados a entrevista semiestruturada, além de uma revisão de documentos da Universidade (Site, Plano de Desenvolvimento Institucional e o Relatório de Responsabilidade Social). Para analisar os dados, utilizou-se a proposta de análise de conteúdo de Bardin, resultando em três categorias pré-estabelecidas: 1ª) Acesso; 2ª) Permanência; e 3ª) Oportunidades. Após analisar as informações obtidas por meio das entrevistas das colaboradoras e documentos da instituição, bem como verificar as medidas estabelecidas na legislação brasileira vigente, concluiu-se que a Universidade está cumprindo com todos os requisitos estabelecidos em lei, além de elaborar ações para prevenir situações inusitadas no acesso, atendimentos personalizados conforme as necessidades individuais para garantir a permanência e um programa de treinamento e de oportunidades de vagas de emprego e estágio remunerado.
A formação da subjetividade empresarial e a implementação da cultura performativa na educação
Authors: Bechi Diego
Published: April 2021

O presente artigo tem por objetivo compreender como a formação da subjetividade de cunho empresarial – produtivista e concorrencial - tem potencializado a construção de uma cultura de permormatividade competitiva no âmbito da educação superior e impactado sobre as condições de trabalho e o modelo/projeto de vida dos trabalhadores docentes. A captura da subjetividade pela racionalidade toyotista/neoliberal, responsável pela formação de um novo sujeito (autogovernável/gestor de si), enseja a elevação da performance individual, de modo a reduzir os custos reais de produção, e o desenvolvimento de uma nova governança do Estado, centrada na privatização e mercadorização das empresas e dos serviços públicos. Assim, o projeto de reterritorialização capitalista vigorou o processo de mercantilização da educação superior, mediante a expansão do setor privado/mercantil e a crescente subordinação das instituições públicas às regras do mercado. A implementação de políticas de cunho mercantilistas e economicistas têm estimulado a generalização da concorrência e o aumento da performance produtiva das instituições de educação superior (públicas e privadas). O medo/instabilidade e a responsabilização, decorrentes das políticas de avaliação quantitativa e de flexibilização das relações e condições de trabalho, compreende a formação (subjetiva) de um novo profissional da educação, mais eficiente, competitivo e subserviente as condições de trabalho precarizadas. Trata-se de um estudo exploratório, quanto aos objetivos, e bibliográfico, de cunho hermenêutico-analítico, quanto aos procedimentos.
A influência dos fatores que estimulam os estudantes universitários em relação à atitude frente ao uso da abordagem do Blended Learning
Authors: Pardim Vanessa Itacaramby , Pinochet Luis Hernan Contreras , Souza Cesar Alexandre de
Published: April 2021

Este artigo se propõe investigar a influência dos fatores que estimulam os estudantes universitários em relação à atitude frente ao uso da abordagem do Blended Learning (BL). O estudo foi realizado em uma Instituição de Ensino Superior particular localizada na Cidade de São Paulo em cursos de graduação. O modelo proposto foi adaptado de Sabah (2019) em um survey (n= 532). A pesquisa apresenta abordagem quantitativa e emprego de Modelagem de Equações Estruturais. Os resultados indicaram que apenas 3 das 25 hipóteses formuladas não foram sustentadas tendo em comum o construto Utilidade Percebida. Diante disso, verificou-se a não obrigatoriedade das atividades on-line, cabendo ao professor apontar a importância do acesso aos materiais antes das aulas, bem como bem como empregar as metodologias ativas; aos tutores estarem à disposição quando demandados e estimular a conscientização da importância das atividades on-line, e, aos colegas de curso para que reconheçam a importância das discussões on-line no processo de aprendizagem. Por fim, os alunos que demonstraram “alta intensidade” em gostar do AVA possuem maior facilidade em perceber as características do BL. Este efeito, também ocorreu na média intergrupal do domínio técnico do AVA (baixo e alto domínio).
Gênero e sexualidades no contexto da universidade pública
Authors: Mendonça Felipe Viero Kolinski Machado , Diniz Margareth , Maia Marta Regina
Published: April 2021

Considerando a universidade como um espaço de interação social e reconhecimento das diferenças, esse trabalho tem como objetivo apresentar e refletir sobre o alcance de um projeto extensionista denominado “Vidas: gênero, diversidade e sexualidades”, desenvolvido na Universidade Federal de Ouro Preto (UFOP) desde 2018. Com uma perspectiva teórica baseada nos estudos pós estruturalistas, na performatividade de gênero (Butler, 2002, 2012) e na Teoria Queer, utilizamos o procedimento metodológico de estudo de caso, que analisa como a existência de projetos (e ações) dessa natureza na universidade pode contribuir para a redução da violência e o reconhecimento da existência da diferença de gênero e de sexualidade no interior da instituição e na região dos Inconfidentes. Os resultados da análise indicam que projetos desse tipo, de caráter multidisciplinar e crítico, assim como políticas institucionais adotadas por universidades, como é o caso da UFOP, contribuem para processos de inclusão e diversidade tão necessários na atualidade.
Formação e envolvimento pedagógico entre docentes do ensino superior em saúde
Authors: Quintanilha Luiz Fernando , Farias Cassiana  Santos da Silva , Andrade Bruno  Bezerril
Published: April 2021

O ensino superior brasileiro passou por expansão significativa nos últimos anos. A combinação de políticas públicas e desenvolvimento socioeconômico do país condicionou um aumento substancial do número de instituições, de vagas, de regiões atendidas por cursos de Medicina e, consequentemente, de professores. Apesar de majoritariamente pós-graduados, esses professores têm treinamento técnico na área específica da Saúde sem, em geral, desenvolverem competências pedagógicas. Dada a importância da Medicina na assistência à saúde brasileira, a formação dos estudantes é tópico fundamental de estudo e de constante melhoria. Avaliar a capacitação do professor, um dos principais atores envolvidos nesse processo, é, portanto, fundamental. O objetivo deste estudo foi avaliar o grau de envolvimento didático-pedagógico dos professores de graduação em Medicina da cidade de Salvador, Bahia. Cento e oitenta professores registrados e atuantes em cursos de graduação de Medicina em instituições de ensino superior da cidade receberam acesso virtual a um questionário estruturado com perguntas referentes à formação e atuação profissional no magistério superior, além de questões de cunho sócio demográficos. Os professores de Medicina, apesar de majoritariamente relatarem conhecer as Diretrizes Curriculares Nacionais do curso, em geral não têm a atividade docente como principal ofício. Além disso, parcela considerável jamais fez nenhum tipo de capacitação pedagógica e baseia sua atuação docente exclusivamente pela experiência prática no seu campo de atuação. O presente estudo demonstra que há muito a ser desenvolvido no âmbito do desenvolvimento docente no ensino médico e propõe maior investimento na capacitação didático-pedagógica desses profissionais.
Detection of Escherichia coli Contamination using Most Probable Number (MPN) methods in Chicken Meats in Market of Surabaya
Authors: Wardhana Dhandy Koesoemo , Safitri Devi Ayu , Annisa Suwaibatul , Effendi Mustofa Helmi , Harijani Nenny
Published: April 2021

Foodborne diseases are diseases transmitted through contaminated food and are one of the main public health problems. The bacteria that usually contaminates chicken meat is Escherichia coli. E. coli contamination in chicken meat can affect consumer health. Chicken meat processing and market conditions affect the level of bacteria contamination. This study aims to measure the contamination of E. coli bacteria in chicken meat in Surabaya's markets. The method which used to count and estimate the number of E. coli bacteria found in chicken meat in this study was Most Probable Number (MPN). The results showed 20 samples (33.3%) from 60 samples gave negative results. This indicated that only 20 samples of chicken meat were safe for consumption because the MPN value is <1 × 101 CFU/g while the remaining 40 samples (66.7%) were not safe for consumption because the MPN value is> 1 × 101 CFU/g. The standard of SNI 3924: 2009 concerning the minimum requirement for the amount of E. coli contamination in chicken meat is 1×101 CFU/g so that the contamination of E. coli which found in chicken meat in Surabaya was high.
Potential Combination of Bittern Water with Vitamin B Complex for Mineral Deficiency Therapy in Cattle: A Literature Study
Authors: Megawati Ega , Bardi Sriwidodo , Setyabudi Iwan
Published: April 2021

Bittern water is a byproduct of the crystallization process from the manufacture of salt which have high concentrations of magnesium, calcium, potassium and other trace minerals Bittern water is known to treat osteoporosis, postprandial hyperlipidemia, oral infections and increase salivary secretion. The mineral content in bittern water is not only beneficial for humans but also for animal health. Cows are one of the animals that are prone to various health problems such as mineral balance and metabolism disorders in the body, especially during pregnancy and after giving birth. In addition to minerals, vitamin B complex is often used to improve the health quality of cows. However, until now, the use of bittern water and the combination with vitamin B complex for animal treatment is still very rare. The formulation of multivitamin-mineral preparations is quite complex to do so that there are several things that need to be considered in order to obtain a good and quality formula. This review article was created to gather information regarding the benefits of the mineral content contained in bittern water and vitamin B complex as a treatment to treat various health problems for cattle, as well as what important factors should be considered in multivitamin-mineral preparations. Based on literature search, it was found that the combination of bittern water and vitamin B complex has the potential to overcome health problems in cows, where the main minerals in bittern water are proven to improve magnesium status in the blood, increase calcium intake and reduce the incidence of milk fever, increase milk production and components, and improve immune status. While vitamin B complex is widely used as a supplement to increase metabolism, energy status in cows balances rumen pH, maintains microbiota balance in riumen and helps increase milk production. The combination of bittern water and vitamin B complex can synergistically improve mineral status, energy, and immune response, as well as improve disease symptoms. There are also important factors that must be considered in multivitamin-mineral dosage formulations for animals, namely bioavailability, stability, and dosage form.
Hindlimb Osteometry of Lohmann Broiler on 7, 21 and 35 days
Authors: Hanafi Ulfiani Fauzia , Dhamayanti Yeni , Purnama Muhammad Thohawi Elziyad , Soeharsono Soeharsono , Wibawati Prima Ayu , Prastiya Ragil Angga
Published: April 2021

Patterns of growth can be determined one of them through quantitative measurements, namely osteometry. The aim of this study was to determine the growth of patterns of Lohmann broiler chickens based on hindlimb osteometry at the age of 7, 21 and 35 days. This study used 30 Lohmann broiler chickens aged 7, 21 and 35 days. Osteometry techniques are performed on all the bones of hindlimb with variable Greatest length (GL), Breadth of the proximal end (Bp), Breadth of the distal end (Dd), Minimum breadth of diaphysis (Sd), Circular of the proximal end (Cp), Circular of corpus (Cc), and Circular of distal end (Cd). The data obtained is recorded in units of centimeters (cm). Data of body weight and weight of each bone are also recorded in grams (g). Data were analyzed by ANOVA test, if the result obtained with a significance of 5% then the test continued with Pos Hoc Duncan. The results showed that from 6 osteometry variables, body weight, and bone mass obtained significant differences (p<0.05). The fastest growth rate is reached when Lohmann broiler chickens are 21 days old.
Bienestar psicológico y engagement en colaboradores de una universidad privada de Lima Metropolitana
Authors:   , Duran Quispe Kerly Stefanny
Published: April 2021

La investigación tuvo como propósito determinar la relación que existe entre las dimensiones del bienestar psicológico y el engagement en colaboradores de una universidad privada de Lima Metropolitana. Para lo cual, se utilizó la Escala de Bienestar Psicológico de Ryff adaptada en Perú por Pérez, M. (2017) y la escala UWES (Utrecht Work Engagement Scale), adaptada al Perú por Hernández, R (2017). La muestra estuvo conformada por 92 trabajadores elegidos bajo un muestreo no probabilístico por conveniencia, con un rango de edad que fluctúa de 20 a 50 años. Los resultados de la investigación demuestran que existe relación estadísticamente significativa entre las variables de este estudio. Asimismo, el bienestar psicológico es mejor explicado bajo la dimensión vigor del engagement, pues la relación es estadísticamente significativa moderada, en las dimensiones relaciones positivas y dominio del entorno.
Resiliencia y apoyo social percibido en profesionales de la salud que se encuentran realizando el Serums 2020
Authors:   , Guerrero Nieto Karen Edith , Quispe Cangahuala Briggitte de los Ángeles
Published: April 2021

La investigación tuvo como propósito determinar la relación entre la resiliencia y el apoyo social percibido en profesionales de la salud que se encontraban realizando el SERUMS en el Perú. Se realizó un estudio de tipo predictivo correlacional de corte transversal y el diseño fue de correlación simple. La muestra estuvo constituida por 150 profesionales de la salud que tenían entre 22 y 45 años (M = 26.7, DE = 3.33), el 76 % eran mujeres, el 62.7% vivían solos. Además, sólo el 66.7% tenía acceso a los servicios básicos de agua, luz, señal de telefonía e internet. Cabe resaltar que todos los participantes brindan sus servicios lejos de su residencia habitual. Los instrumentos de medición fueron “Escala de Resiliencia CD-RISC 7” una escala unidimensional, analizado por Dominguez-Lara et al. (2019). Para medir la siguiente variable se usó el “Cuestionario de Apoyo Social Percibido” adaptado por Baca (2016), este instrumento posee dos áreas: Estructural y Funcional. Los resultados obtenidos, demuestran que no existe relación estadísticamente significativa entre la resiliencia y el apoyo social estructural. (r = .096; p> .05). Sin embargo, se encontró una relación estadísticamente significativa, positiva débil entre la resiliencia y el apoyo social funcional (r = .179; p< .05). Tras los resultados obtenidos, se infiere la no existencia de una correlación estadísticamente significativa entre ambas variables.
Satisfacción laboral y engagement en empleados del servicio de alimentación de campamentos mineros
Authors:   , Ríos More Rodrigo Alberto
Published: April 2021

La presente investigación tuvo como objetivo determinar la relación entre satisfacción laboral y engagement en empleados del servicio de alimentación ubicados en los campamentos mineros de Moquegua, Cerro de Pasco y Ayacucho. Se tuvo como muestra 107 empleados cuyos rangos de edad fueron de 20 y 50 años. Asimismo, se utilizaron los inventarios de Ultrech Work Engagement Survey (UWES) y el Cuestionario de Satisfacción Laboral (S20/26). Los resultados prueban la existencia de la relación entre el vigor y dedicación con la satisfacción con la supervisión (r = .274, r = .322), satisfacción intrínseca (r = .359, r = .417), satisfacción con la producción (r= .287, r=3.27) y satisfacción con la participación (r = .316, r = .351). Se puede concluir que las variables vigor y dedicación tienen una relación con satisfacción con la supervisión, satisfacción intrínseca, satisfacción con la calidad de producción y satisfacción con la participación.
Theory of Games and Theory of International Relations
Authors: Degterev D. , Degterev A.
Published: April 2021

The author proposes a historiographical study of the game theory application to the analysis of international negotiations, conditions for modification of multilateral regimes, mechanisms of decision-making in the international organizations. Game theory is a mathematical theory for analysis of strategic behavior (interaction) and it is widely used in the social sciences. It explains the logic of rational behavior of individuals in situations of conflict of interest. Game theory is used by foreign researchers as a method of analysis of international relations. The domestic researchers, however, do not often resorts to it. The “golden age” of game theory was the era of global confrontation between the USSR and the United States.
Russia and Competition for Remaking Sub-Polar Spaces
Authors: Fenenko A.
Published: April 2021

The article analyzes the problem of revising the interstate borders in the Arctic and the Antarctic legal status. These issues have repeatedly arisen in the international relations. However, the fight for control of circumpolar territories used to be episodic and conducted mainly by diplomatic means. Nowadays, the Arctic powers began to dispute the revision of the boundaries of the Arctic sectors and the distribution of the “oceanic co-management” system on the Arctic Ocean. The debates are conducted concerning the boundaries of the Southern Ocean’s sectors, on the status of the territories adjacent to the Antarctic and on a return to the drafts of sectoral division of Antarctic. These trends increase the risk of interstate confrontation in circumpolar areas. For Russia a possible redistribution of polar spaces does not mean anything positive.
Crisis in Greece
Authors: Kvashnin Y.
Published: April 2021

The author points out that, despite some success in 2010, the medium-term prospects of Greece do not inspire much optimism. Even in the case of a quick recovery of the world economy in the next two years (which is highly questionable), the country will face a continuation of the recession. It is very likely that in the near future the government will have to restructure public debt, which reached 125% of GDP by 2010. Besides that, Greece faces a very difficult foreign policy challenge, that is to restore the credibility from the EU and to prove that Greece’s admittance to the Eurozone was not a mistake.
Problem of Global Warming: Japan’s Policy
Authors: Strel’tsov D.
Published: April 2021

The article analyzes the initiative put forward by the Prime-Minister of Japan Yukio Hatoyama in September 2009 pledging that Japan will reduce its greenhouse gas emissions by 25% by 2020 from 1990 levels. The initiative has become an organic succession of Japan’s long-term strategy aimed at building a low carbon society. The perspective of the realization of the initiative will depend on the readiness of other countries to take their own responsibility for the emission cuts.
Method of Comparative and Institutional Analysis
Authors: Nisnevich Y.
Published: April 2021

This paper presents the method of the contrastive-institutional analysis, which essence is in comparison of different state characteristics in order to reveal interrelations and influence trends existing between states. The results of state-studies carried out by international and nongovernmental organizations serve as basic information. The example of the application of this method is also given in the article.
Influence of Strategic Offensive Armaments in Non-Nuclear Outfit on Strategic Stability
Authors: Anin A.
Published: April 2021

The article deals with one of the most pressing issues in the spring of 2010 at the concluded Russian-American negotiations on a new START Treaty (DSNV-2010), namely to the issue of strategic non-nuclear offensive armaments (SNOA). As the author argues, the Russian and Western expert communities are is just beginning to analyze what has been achieved in this respect at DSNV-2010. Despite all the difficulties in the negotiating process, new DSNV includes an agreement on a temporary compromise to alleviate the problem.
Modern Trajectories of Party Systems’ Development at Post-Soviet Space
Authors: Grigorenko E.
Published: April 2021

This paper is focused on two dimensions, which are considered to be essential for understanding of post-Soviet dynamics of party systems that are level of elite consolidation and role and potential of ruling party. Based on their analysis 5 types of party systems are singled out, starting from quite competitive ones to party systems characterized by insignificant role of parties, which are playing minor role in political agenda-setting. Besides, analysis of economic, socio-cultural and institutional determinants and modernization level reveals their possible impact on trajectories of party systems development.
Suton međunarodnog liberalnog poretka, dijalektika političke mehanike i novi Vestfalski sistem za 21. vek
Authors: Cvetićanin Neven , Mandić Marko
Published: April 2021

Autori ovog rada nude pregled i analizu uspona i pada međunarodnog liberalnog‎ poretka koji je nastao nakon okončanja Hladnog rata i uspona moći Sjedinjenih‎ Američkih Država. Spoljnopolitička agenda jedine posthladnoratovske‎ supersile vođena je idejom stvaranja globalnog poretka utemeljenog na ideologiji‎ (globalnog) liberalizma koja u sebi inkorporira teorije liberalnog mira,‎ demokratskog mira i neoliberalnog institucionalizma. Uspostavljanje tzv. globalnog‎ liberalnog poretka dosada je bilo praćeno brojnim političkim, socijalnim,‎ ekonomskim i bezbednosnim krizama, a trenutnu eru međunarodnih odnosa‎ odlikuju uspon relativne moći “neliberalnih” globalnih aktera, pre svega‎ Kine i Rusije, kao glavnih izazivača svetske dominacije Sjedinjenih Američkih‎ Država, te geopolitički revizionizam i ideološka konfrontacija liberalnih i‎ antiliberalnih snaga širom sveta. Autori ovog rada koriste specifičan analitički‎ metod tzv. dijalektike političke mehanike, koji se oslanja na učenja Friedricha‎ Hegela o dijalektici istorije i Carla Schmitta o fenomenu političkog, kako bi‎ objasnili trenutnu dinamiku međunarodnih odnosa, pokazujući da političko‎ polje “permanentno pulsira” što, u svemu što je društveno i političko, nužno‎ kreira akciju i reakciju, čijom dinamikom se mogu tumačiti i globalna zbivanja‎ kojima upravo prisustvujemo.‎
Cell Proliferation in the Piriform Cortex of Rats with Motor Cortex Ablation Treated with Growth Hormone and Rehabilitation
Authors: Heredia Margarita , Sánchez-Robledo Virginia , Gómez Inés , Criado José María , Fuente Antonio de la , Devesa Jesús , Devesa Pablo , Riolobos Adelaida Sánchez
Published: April 2021

Traumatic brain injury represents one of the main health problems in developed countries. Growth Hormone (GH) and rehabilitation have been claimed to significantly contribute to the recovery of lost motor function after acquired brain injury, but the mechanisms by which this occurs are not well understood. In this work, we have investigated cell proliferation in the piriform cortex (PC) of adult rats with ablation of the frontal motor cortex treated with GH and rehabilitation, in order to evaluate if this region of the brain, related to the sense of smell, could be involved in benefits of GH treatment. Male rats were either ablated the frontal motor cortex in the dominant hemisphere or sham-operated and treated with GH or vehicle at 35 days post-injury (dpi) for five days. At 36 dpi, all rats received daily injections of bromodeoxyuridine (BrdU) for 4 days. We assessed motor function through the paw-reaching-for-food task. GH treatment and rehabilitation at 35 dpi significantly improved the motor deficit caused by the injury and promoted an increase of cell proliferation in the PC ipsilateral to the injury, which could be involved in the improvement observed. Cortical ablation promoted greater number of BrdU+ cells in the piriform cortex that was maintained long-term, which could be involved in the compensatory mechanisms of the brain after injury.
HBV Pre-S1-Derived Myristoylated Peptide (Myr47): Identification of the Inhibitory Activity on the Cellular Uptake of Lipid Nanoparticles
Authors: Nanahara Masaya , Chang Ya-Ting , Somiya Masaharu , Kuroda Shun’ichi
Published: April 2021

Myr47 lipopeptide consisting of hepatitis B virus (HBV) pre-S1 domain (myristoylated 2-48 peptide) is a commercialized effective anti-HBV drug, preventing the interaction of HBV with sodium taurocholate cotransporting polypeptide (NTCP) on human hepatocytes, of which the activity requires both N-myristoylation residue and specific amino acid sequence. Meanwhile, we recently reported that Myr47 reduces the cellular uptake of HBV surface antigen (HBsAg, subviral particle of HBV) in the absence of NTCP expression (Somiya; et al. Virology 2016, 497, 23–32). In this study, we analyzed how Myr47 reduces the cellular uptake of lipid nanoparticles (including liposomes (LPs) and HBsAg) without NTCP expression. By using Myr47 mutants lacking the HBV infection inhibitory activity, they could reduce the cellular uptake of LPs in an N-myristoylation-dependent manner whereas in an amino acid sequence-independent manner. Moreover, Myr47 and its mutants could reduce the interaction of LPs with apolipoprotein E3 (ApoE3) in an N-myristoylation-dependent manner regardless of their amino acid sequences. From these results, N-myristoyl residue of lipopeptides generally could interfere the LPs/HBsAg-ApoE3 complex formation, thereby reducing the cellular uptake of LPs/HBsAg. When lipid nanoparticles are used as a DDS (drug delivery system) nanocarrier, the surface modification with lipopeptides may be a new method to inhibit unwanted cellular uptake of DDS nanocarriers by non-target cells.
Microsatellites as Agents of Adaptive Change: An RNA-seq based Comparative Study of Transcriptomes from Five Helianthus Species
Authors: Ranathunge Chathurani , Pramod Sreepriya , Renaut Sébastien , Wheeler Gregory , Perkins Andy , Rieseberg Loren H , Welch Mark E
Published: April 2021

Mutations that provide environment dependent selective advantages drive adaptive divergence among species. Many phenotypic differences among related species are more likely to result from gene expression divergence rather than from non-synonymous mutations. In this regard, cis-regulatory mutations play an important part in generating functionally significant variation. Some proposed mechanisms that explore the role of cis-regulatory mutations in gene expression divergence involve microsatellites. Microsatellites exhibit high mutation rates and are abundant in both coding and non-coding regions and could influence gene function and products. Here we tested the hypothesis that microsatellites contribute to gene expression divergence among species with 50 individuals from nine closely related Helianthus species using an RNA-seq approach. Differential expression analyses of the transcriptomes revealed that genes containing microsatellites in non-coding regions (UTRs and introns) are more likely to be differentially expressed among species when compared to genes with microsatellites in the coding regions and transcripts lacking microsatellites. We detected a greater proportion of shared microsatellites in 5’UTRs and coding regions compared to 3’UTRs and non-coding transcripts among Helianthus spp. Further, allele frequency differences measured by pairwise FST at single nucleotide polymorphisms (SNPs), indicate greater genetic divergence in transcripts containing microsatellites compared to those lacking microsatellites. A gene ontology (GO) analysis revealed that microsatellite-containing differentially expressed genes are significantly enriched for GO terms associated with regulation of transcription and transcription factor activity. Collectively, our study provides compelling evidence to support the role of microsatellites in gene expression divergence.
Real-Time Visual Feedback Control of Multi-Camera UAV
Authors: He Dongqing ,   Chiba Unversity 1-33 Yayoi-cho, Inage-ku, Chiba-shi, Chiaba 263-8522, Japan, Chuang Hsiu-Min , Chen Jinyu , Li Jinwei , Namiki Akio
Published: April 2021

Recently, flight control of unmanned aerial vehicles (UAVs) in non-global positioning system (GPS) environments has become increasingly important. In such an environment, visual sensors are important, and their main roles are self-localization and obstacle avoidance. In this paper, the concept of a multi-camera UAV system with multiple cameras attached to the body is proposed to realize high-precision omnidirectional visual recognition, self-localization, and obstacle avoidance simultaneously, and a two-camera UAV is developed as a prototype. The proposed flight control system can switch between visual servoing (VS) for collision avoidance and visual odometry (VO) for self-localization. The feasibility of the proposed control system was verified by conducting flight experiments with the insertion of obstacles.
Assessment of Knowledge, Attitude, Perception of Pharmacy Students Towards Telepharmacy
Authors:   University of Tennessee Health Science Center, Patel Komal
Published: April 2021

Telemedicine is one of the fastest growing area in health care technology and COVID-19 pandemic has changed the way of practicing Telemedicine. Telepharmacy is a part of telemedicine where pharmacy use this technology to provide patient care services. Success of any technology depends on users’ willingness to learn and attitude towards technology. Early assessment of students’ attitude during pharmacy school is important to know in order to assess how receptive students are to accept Telepharmacy in their work setting currently or in future. That will also help to determine success of Telepharmacy implementation. This study will focus on assessing knowledge, attitude and perceptions of student pharmacists towards Telepharmacy.
Attenuation of Interferon Responses in the Obese Host and Ramifications for Influenza Virus Evolution
Authors:   ,   University of Tennessee Health Science Center, Honce Rebekah
Published: April 2021

The most insidious pandemic of modern life does not arise from an infectious agent but rather from malnutrition. With its global incidence tripling over the past three decades, obesity is a major public health concern. Obesity’s rising prevalence has also illuminated its impact on communicable diseases. Following the 2009 H1N1 influenza A virus pandemic, obesity was identified as a risk factor for increased disease severity and mortality in infected individuals. Obesity causes a chronic state of meta-inflammation with systemic implications for immunity, including delayed antiviral responses to influenza virus infection, poor recovery, and impaired immunological memory. However, the majority of past work neglected the innate responses, especially the impact on the epithelium. To better understand the innate response to influenza infection, obese animal models and human respiratory epithelial cells were inoculated with influenza viruses to quantify the innate responses. In obese hosts, antiviral effector production, including type I and type III interferons, was consistently blunted across all model systems and linked to a highly oxidative, pro-inflammatory environment. This interferon-deficient state altered the host microenvironment in which influenza replicated, spread, and caused disease. Due to the inherent mutability and segmented nature of influenza virus, this altered microenvironment also had implications for the genetic drift and shift of the viral population. Compared to infection of lean hosts, minor variants rapidly emerged within the viral population in obese hosts which exhibited increased viral replication, enhanced virulence, and antiviral resistance. The delayed action of interferon also permitted greater rates of reassortment. Together, this suggested obesity permitted the emergence of novel, and potentially pathogenic, viral variants. Influenza viruses pose constant seasonal and pandemic threats with high morbidity and mortality suffered by overweight and obese patients. If current trends continue, nearly half of the worldwide population will be obese by 2050. This population will have growing impacts on both non-communicable and communicable diseases and may affect global evolutionary trends of influenza virus.
Eukaryotic Initiation Factor 5A2 (EIF5A2) Contributes to Ovarian Tumor Growth and Metastasis
Authors:   ,   University of Tennessee Health Science Center, Zhao Guannan
Published: April 2021

Ovarian cancer has the highest mortality rate among all gynecological malignancies due to lack of effective biomarkers for early diagnosis. The majority of ovarian cancer patients are already at an advanced stage when diagnosed. In addition, ovarian cancers often become chemoresistant and metastatic, and recur following initial chemotherapy.
Modeling the effect of increased sediment loading on bed elevations of the Lower Missouri River
Authors: Shelley John
Published: April 2021

This US Army Corps of Engineers (USACE) National Regional Sediment Management Technical Note (RSM-TN) documents the effects of increased sediment loading to the Missouri River on bed elevations in the lower 498 miles. This was accomplished using a one-dimensional (1D) HEC-RAS 5.0.7 sediment model.
TERRORIST ATTACKS AND CORPORATE INVESTMENT IN INDONESIA
Authors: Nguyen Dat Thanh , Phan Dinh Hoang Bach , Nguyen Van Ky Long
Published: April 2021

Using yearly data from 1997 to 2017, this paper studies the effect of terrorism (number of attacks) on corporate investment in Indonesia. Applying an investment-type model, we show that firms reduce their capital expenditure due to an increase in the number of terrorist attacks. On average, a one standard deviation increase in the number of terrorist attacks reduces corporate investment by 9.23%. We also find heterogenous reactions of firms to terrorism across different sectors and different panels based on firm characteristics. Finally, our main results remain consistent after performing several robustness tests.
ADJUSTMENT SPEED OF DEBT MATURITY: EVIDENCE FROM FINANCIAL CRISES IN EAST ASIA
Authors: Tekin Hasan , Polat Ali Yavuz
Published: April 2021

We investigate the change in adjustment speed of debt maturity for East Asian firms between 1990 and 2017 by including two exogenous shocks: the Asian Financial Crisis 1997-1998 (AFC) and the Global Financial Crisis 2007-2009 (GFC). We employ the least square dummy variable correction and find that East Asian firms have a slower adjustment of long-term debt over time. Besides, the decrease in adjustment speed of long-term debt after the GFC is more compared to the decrease after the AFC. Further analysis shows the optimal debt maturity differs across countries and industries. Another important implication of our results is that firms in high governance countries are more likely to close the gap between the actual and target debt maturity in time. Overall, debt holders and investors should consider financial uncertainties.
SPILLOVER EFFECTS OF EXCHANGE RATE RETURNS IN SELECTED ASIAN COUNTRIES
Authors: Devpura Neluka
Published: April 2021

We analyze the nature of exchange rate return spillovers for 16 currencies. We use 10 years of daily exchange rate data, covering January 01, 2010 to December 31, 2019. By using the spillover index proposed by Diebold and Yilmaz (2009, 2012), we provide empirical evidence on the spillover of exchange rate returns among the Asian countries. The largest spillover flows from the Singapore dollar to other currencies (16.49%). Overall, our results confirm the presence of exchange rate return spillovers within the Asian countries and about 22% of the forecast error variance is due to spillovers.
DOES ECONOMIC INTEGRATION INCREASE FEMALE LABOUR FORCE PARTICIPATION? SOME NEW EVIDENCE FROM VIETNAM
Authors: Narayan Seema Wati , Nguyen Tri Tung , Nghiem Xuan-Hoa
Published: April 2021

While several studies have, directly or indirectly, showed the importance of economic integration in job creation and destruction, direct empirical evidence for Female Labor Force Participation (FLFP) is still sparse. We take the case of Vietnam – a country that has come out of poverty largely due to her export-induced economic growth – and examine the impacts on FLFP of economic integration over the period 1999-2014. Our results suggest that Vietnam’s export sector, which relies heavily on foreign direct investment and free trade agreements, is an important contributor to FLFP. Economic integration with high-income countries (compared to middle- and low-income countries) was found to be most beneficial to FLFP in Vietnam. Our results also indicate that some traditional drivers of FLFP (such as fertility rate, health status, female adolescents out of secondary school, government education spending, and standard of living) became more (or less) important as Vietnam became more economically integrated.
An improved and highly efficient geometry for facemasks
Authors: Cappa Christopher , Ristenpart William , Barreda Santiago , Bouvier Nicole , Wexler Anthony , Roman Sanziana , Department The San Francisco Opera Costume
Published: April 2021

Wearing masks and face coverings helps reduce transmission of respiratory diseases. Much prior research on mask filtration efficiency has focused on fabric type, with little consideration given to mask geometry. Here, we present evidence that increasing the mouth-mask separation distance engenders an increase in the mask-fabric filtration efficiency towards expiratory aerosols emitted via vocalization, which we attribute to a decrease in the expiratory jet velocity. We further assess the performance of a new reusable cloth facemask design, originally made for professional singers and having a large mouth-mask separation distance. With proper fitting, these masks achieve overall filtering efficiencies of >93% for both exhaled expiratory aerosols from singing and speaking and for inhaled ambient aerosols, better than surgical masks and approaching N95 respirators. The mask design also provides for less inhibited mouth and jaw movement, suggesting it may provide a more palatable, high-efficiency alternative to medical-grade masks for the public.
Processing Technique Selection for Steels Based on Mechanical Properties Using Machine Learning Framework
Authors: Choudhury Amitava
Published: April 2021

Prediction of process route from materials with a desired set of property is one of the fundamental issues in the perspective of the materials design aspect. The parameter space is often too large to be bound since there are too many possibilities. However, in the areas with limited theoretical access, artificial learning techniques can be attempted by using the available data of the candidate materials. In this study, a computational method has been proposed to predict the different process routes of steel constituted taking composition and desired mechanical properties as inputs. First of all, historical data of the actual rolling process was collected, cleaned, and integrated. Further, the dataset is divided into four different classes based on the rolling process data. Then, to find out the essential characteristics of variables, feature correlation among various features has been calculated. A state-of-art machine learning prediction methods such as logistic regression, K- nearest neighbor, Support vector machine, and the random forest are studied to implement the prediction model. In order to avoid the overfitting of the model, k fold cross-validation is applied to the model, and achieve a realistic prediction result with an accuracy of 97%. The F1-score of the classification model is 0.86, and the kappa score is 0.95, which comply that the model has excellent learning and speculation ability and the precise forecast of steel process routes based on the given input parameters.
Study On Critical Temperatures For Naphthalene And Chlorobenzene Removal During In Situ Steam Injection Remediation
Authors: Liu Ru xue , Yang Xinru , Zhao Yongsheng
Published: April 2021

Steam injection is an effective technique for the in situ remediation of volatile and semi-volatile organic contaminants. In this study, the influence of temperature and media on the removal of organic pollutants, such as naphthalene and chlorobenzene, was investigated in the remediation process through batch and remediation experiments, and the solid, liquid, and gaseous phase migration and transformation of organic pollutants during remediation were evaluated. The results demonstrated that the temperature significantly influenced the removal of organic pollutants. It was found that the critical temperatures for naphthalene and chlorobenzene were 50°C and 30°C, respectively. When the temperature was higher than the critical temperature, the final removal rates of naphthalene and chlorobenzene reached over 94% and 96%, respectively. The remediation area of chlorobenzene determined according to the critical temperature has a good result; the error compared with the actual remediation area in both coarse sand and fine sand was approximately 8.7%. In the simulation tank, the temperature changes can be divided into three stages: the ambient temperature stage, the temperature rapid rise stage, and the stable stage. Moreover, we found that the remediation effect of aquifers is not only related to temperature, but also to the location of the SVE well (soil vapour extraction). These findings reveal the main factors affecting the application of hot steam technology and the relationship between the temperature field and contamination field in the remediation process.