bluuebunny/crossref_metadata_2025 huggingface dataset:
Health Risk Assessment for Ingestion of Edible Mushrooms Contaminated by Chromium
Authors: de Lucio-Flores Sharon Alethia , Gaytan-Oyarzun Juan Carlos , Garibay-Orijel Roberto , Pulido-Flores Griselda
Published: August 2024

A health risk assessment was carried out to determine the probability of damage and carcinogenic effects from consumption of five mushroom species (Boletus edulis, Cantharellus cibarius, Lactarius indigo, Ramaria flava, and Sarcodon calvatus) potentially contaminated by chromium (Cr), based on data reported by López-Vázquez and Prieto-García (2016) in Hidalgo state [López-Vázquez E, Prieto-García F. Minerals and toxic elements in wild mushrooms species from regions of Hidalgo state in Mexico. Asian J Chem. 2016;28(12):2725-30]. The evaluation was carried out based on an environmental risk indicator: potential ecological risk; and two health risk indicators: the hazard quotient, non-cancer damage and the risk of increase of individual cancer. The results showed that there is a high probability of carcinogenic damage for the three regions where older adults and pregnant are the most vulnerable sectors. Due to the traditional use of edible mushrooms in Mexico, the evidence of bioaccumulation of heavy metals of toxicological interest in mushroom species, as well as the notable damage to health due to the consumption of contaminated species; the monitoring and implementation of standards that regulate their consumption and ensuring their food safety is essential. More research is required to support the use of these evaluations.
Key influence factors of carbon dioxide emissions in Malaysian construction operations
Authors: Joseph Verona Ramas , Mustaffa Nur Kamaliah , Rani Izzaty Abdul , Isa Che Maznah Mat
Published: August 2024

The urgency to mitigate carbon dioxide emissions (‘carbon emissions’) has gained significant societal attention as the consequences of climate change continue to unfold. There is a notable scarcity of studies conducted on carbon emissions for construction operations. Hence, the aim is to identify the key influence factor of carbon emissions to develop a carbon dioxide reduction framework for construction operations. A survey was conducted with 297 Malaysian construction stakeholders to analyse 18 factors. Descriptive and Rasch analyses were used. The results revealed the reliability and validity of the model, which could help explore ways to reduce carbon emissions during the construction phase. The findings indicate that a gradual transformation process is necessary to expedite the transition towards low carbon dioxide construction. The research enhances the existing literature by emphasising the key factors for stakeholders who aim to manage carbon emissions efficiently during a construction project. There are different ideas on how to estimate and manage carbon emissions in construction projects, but there are no standardised ways. This study looks into the main factors that contribute to the generation of carbon emissions in construction, to identify ways to reduce them, evaluating these factors from the perspective of different stakeholders.
Auto Finance in the Electric Vehicle Transition
Authors: Klee Elizabeth , Morse Adair , Shin Chaehee
Published: August 2024

Financing cost differentials tilt the calculus for households toward electric vehicles (EVs). Using 85 million observations on U.S. auto loans, we study households’ credit risk by engine type, seek to uncover the sources and ask if credit risk differentials are being priced. We find that EV borrowers default 29% less relative to internal combustion engine vehicle (ICEV) borrowers with a back-of-the-envelope value of $1,457 in lender savings. To disentangle selection from expost exposure to differential costs of running an EV, we implement a differential shock exposure by treatment model of Borusyak and Hull (2023). Do lenders passalong these savings to borrowers? EV borrowers pay 2.2 percentage point lower interest rate, the equivalent of $2,711 in foregone payments. This lower rate is only for captive (manufacturer-based) lenders, not for bank and nonbank lenders, suggestive of policy and strategic motives by manufacturers, not a passing along of credit risk value. Another $1,457 is probably not being priced to households. Finally, we find that the ABS market knows, at least partially, allowing for less in loan loss reserves buffering the ABS, reflecting $233 in savings for the ABS issuer.
Interconnectedness in the Corporate Bond Market
Authors: Brunetti Celso , Carl Matthew , Gerszten Jacob , Scotti Chiara , Shin Chaehee
Published: August 2024

Does interconnectedness improve market quality? Yes.We develop an alternative network structure, the assets network: assets are connected if they are held by the same investors. We use several large datasets to build the assets network for the corporate bond market. Through careful identification strategies based on the COVID-19 shock and “fallen angels,” we find that interconnectedness improves market quality especially during stress periods. Our findings contribute to the debate on the role of interconnectedness in financial markets and show that highly interconnected corporate bonds allow for risk sharing and require a lower compensation for risk.
The Effect of Export Market Access on Labor Market Power: Firm-level Evidence from Vietnam
Authors: Hoang Trang , Mitra Devashish , Pham Hoang
Published: August 2024

We examine the impact of an export market expansion created by the US-Vietnam Bilateral Trade Agreement (BTA) on labor market competition among Vietnamese manufacturing firms. We measure distortionary wedges between equilibrium marginal revenue products of labor (MRPL) and wages nonparametrically and find that the median firm pays workers 59% of their MRPL. The BTA permanently decreases labor market distortion in manufacturing by 3.4%, mainly for domestic private firms. The median distortion is 26% higher for women than men, and the decline in distortion for women drives the overall distortion reduction. We shed some light on the mechanisms for these results.
Editorial
Authors: Lara-Largo Sofía , Suárez Guava Luis Alberto
Published: August 2024

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Tiempo-espacio, identidad e insurrección. El método ch’ixi de Silvia Rivera Cusicanqui: puentes entre el anarquismo y la cosmovisión aymara
Authors: Mäkimartti Mikko , Makaran Gaya
Published: August 2024

El presente artículo se propone una sistematización, una puesta en diálogo y la explicitación de las correspondencias entre la teoría anarquista y la filosofía aymara del método ch’ixi de la socióloga boliviana Silvia Rivera Cusicanqui. Primeramente, se esboza el contexto sociohistórico e intelectual en el que se desarrolla la vida y el pensamiento de la autora, Bolivia, con su abigarramiento social zavaletiano y su larga tradición de praxis anticolonial, donde el indianismo, el anarquismo y la apuesta por la descolonización efectiva jugarán un papel crucial. Posteriormente, se mostrará que el método ch’ixi, negativamente dialéctico, antiesencialista y anticolonial tiene raíces metafísicas y teóricas tanto anarquistas como aymaras, en cuanto a la dialéctica sin síntesis, la complementariedad y la regla del tercero incluido. Se sugiere un diálogo con la misma autora que, aunque declara abiertamente su anarquismo: “anarca-ch’ixi”, no necesariamente hace explícitas todas sus posibles referencias y diálogos con esta tradición, igual que sus puentes con la cosmovisión aymara. De ahí ordenamos nuestra reflexión según tres ejes que atraviesan su pensamiento y al mismo tiempo son atravesados por su método: el tiempoespacio (pacha), la identidad y la insurrección como praxis anticolonial. Se cerrará con unas reflexiones abiertas que den cuenta de la importancia del método ch’ixi para el análisis de las realidades latinoamericanas —si no globales— y de los retos que supone y que todavía esperan investigaciones futuras.
Leer los cuerpos: reflexiones sobre las prácticas estéticas en un grupo de mujeres negras en Cali
Authors: Zúñiga Delgado David Eloy
Published: August 2024

El presente artículo ahonda sobre cómo influye la estética corpórea, la del cabello y la del vestuario en la construcción identitaria en un grupo de mujeres negras integrantes de una organización de base dedicada al trabajo con comunidades afrocolombianas en Cali (Colombia). Con un diseño cualitativo de carácter transversal, mediante entrevistas estructuradas a profundidad a diez integrantes de la Asociación de Mujeres Afrocolombianas, AMAFROCOL; revisión bibliográfica; estudio de material audiovisual; y observación participante, se realizó un análisis de diferentes dimensiones sociales y sustantivas que sitúan la categoría “identidad” como un elemento relacional y no esencial. Finalmente, se concluye que el cabello, lo corpóreo, las formas de vestir y la pertenencia a una organización de corte étnico influyen significativamente en los procesos de construcción de la identidad étnica en contextos urbanos.
Mot d’ouverture
Authors: Vukušić Zorica Maja
Published: August 2024

The 22nd edition of the European Summer School of the OFFRES network (Frenchspeaking Organization for European Training and Research in humanities) in the CAAS (Centre for Advances Academic Studies) in Dubrovnik (23-30.07.2023), under the title “On the usefulness and the disadvantages of adaptation under the aegis of Molière”, aimed to commemorate the 400 years of birth and the 350 years of death of Molière (1622-1673), while transposing the question of adaptation into the field of Humanities. This edition was organized by the network (Chiara Mengozzi, Chiara Pesaresi) and Maja Vukušić Zorica from the University of Zagreb. It brought together professors and specialists in Humanities, Ph.D. and MA students (and this year some BA students), a total of 52 people from 30 countries including 23 professors, 9 foreign Ph.D. students, 1 foreign student and 19 (!) Croatian students of French Language and Literature from the Faculty of Humanities and Social Sciences in Zagreb. All students participated in 6 workshops and presented the results of their work. This edition of the Summer School is presenting for the first time not only the articles of plenary speakers, but also the work of the students with the specialists that led the workshops, which are, for most of them, the crucial first steps in their future scientific career. The University of Zagreb recognized our efforts and awarded 3 ECTS points to this edition of our Summer School.
Теоретический расчет параметров метода трехпараметрической характеристики хроматографических фаз I. Параметр дисперсионных сил – обобщенный заряд
Authors: Зайцева Елена Александровна , Долгоносов Анатолий Михайлович
Published: August 2024

Селективность разделения в газовой хроматографии определяется природой неподвижной фазы. В рамках предложенной авторами ранее модели межмолекулярных взаимодействий и разработанного на ее основе теоретического метода трехпараметрической характеристики хроматографических неподвижных жидких фаз делается количественная оценка способности молекул к участию в дисперсионных, диполь-дипольных взаимодействиях и в водородных связях. Метод показал свою эффективность при описании свойств неподвижных фаз на основе углеводородов, полиэтиленгликоля, полисилоксанов и ионных жидкостей. Свойства неподвижных фаз и молекул аналитов описываются двумя характеристиками селективности: полярностью и гидрофильностью, которые могут быть рассчитаны по прямой задаче по структурной формуле вещества и по обратной задаче по экспериментальным данным в виде индексов удерживания Ковача или констант Роршнайдера-МакРейнольдса; противоречия между результатами расчета характеристик двумя способами обнаружено не было. С помощью предложенного метода была выявлена связь между молекулярной массой полимерной молекулы и величинами характеристик селективности. Предложена карта селективности как удобный наглядный способ классификации неподвижных фаз, которая может быть применена в сочетании с принципом подобия свойств для выбора наиболее селективной к заданным аналитам неподвижной фазы; этот выбор может быть сделан без проведения экспериментов. Предлагаемая работа посвящена определению обобщенного заряда как первого и ключевого параметра метода трехпараметрической характеристики. Основным инструментом послужила разработанная ранее в лаборатории сорбционных методов ГЕОХИ РАН теория обобщенных зарядов. Эта теория, выведенная из фундаментальных принципов, описывает ван-дер-ваальсовы взаимодействия в виде потенциала Леннард-Джонса с помощью характеристик молекул, определяемых из молекулярной структуры. Ранее с ее помощью были успешно описаны неполярные хроматографические системы. В работе даны определения обобщенных зарядов, показана их связь с физическими и экспериментальными величинами, приведены расчетные формулы для изолированных молекул и для жидких фаз. Представлены результаты детального расчета обобщенных зарядов веществ разных классов, включающих в себя газохроматографические неподвижные фазы.
Хроматографический анализ аминокислотного состава желчных камней
Authors: Машина Екатерина Валерьевна , Шанина Светлана Николаевна , Амосова Ольга Евгеньевна
Published: August 2024

Желчнокаменная болезнь (холелитиаз) – многофакторное заболевание, характеризующееся образованием желчных камней. Изучение состава желчных камней необходимо для установления механизма их образования и решения многих практических вопросов. На данный момент, неясно, какая белковая компонента участвует в формировании желчных камней и как она связана с их составляющими. В работе показана возможность качественного и количественного определения аминокислот в составе желчных камней мужчин и женщин разного возраста с использованием метода газовой хроматографии GC-17A (Shimadzu). Анализ аминокислотного состава желчных камней включает в себя кислотный гидролиз образцов с 6М HCl при 105оС в течение 12 часов, последующую очистку, получение производных выделенных аминокислот и их определение методом газовой хроматографии. Данная методика позволяет определять D- и L-формы аминокислот. Статистическая обработка полученных данных осуществлялась с помощью программы Statistica 6.0. В результате проведенного исследования установлено, что желчные камни холестеринового состава, принадлежащие женщинам, возраст которых не превышал 50 лет, характеризуются самыми низкими содержаниями аминокислот. В аминокислотном составе холестеринового типа камней преобладают глицин и L-формы серина, аланина и глутаминовой кислоты. Холестериновые камни с минеральной компонентой характерны для пожилых женщин (старше 60 лет) и мужчин среднего возраста (от 37 лет), и имеют более высокие содержания аминокислот, чем холестериновые желчные камни. В данном типе камней преобладают глицин и L-формы лейцина, глутаминовой кислоты, аспарагиновой кислоты. Самые высокие содержания аминокислот установлены в пигментных камнях, как у мужчин, так и у женщин старше 55 лет. В аминокислотном составе камней пигментного типа преобладают глицин и L-формы глутаминовой кислоты, аспарагиновой кислоты, лейцина, аланина. В желчных камнях холестеринового состава D-аминокислоты не обнаружены. В холестериновых камнях с минеральной компонентой и пигментных желчных камнях установлена D-аспарагиновая кислота. Полученные результаты позволяют рекомендовать метод газовой хроматографии для изучения аминокислотного состава желчных камней.
Изучение хроматографических свойств разработанного гиперразветвленного цвиттер-ионного сорбента на основе силикагеля в режиме гидрофильной хроматографии
Authors: Максимов Григорий Сергеевич , Шемякина Анна Олеговна , Ужель Анна Станиславовна , Чернобровкина Алла Валерьевна
Published: August 2024

Целью данной работы являлось получение неподвижной фазы для гидрофильной хроматографии с гиперразветвленным функциональным слоем, содержащей цвиттер-ионные группы, и изучение её хроматографических свойств с использованием модельных веществ разнообразных кислотно-основных характеристик. В качестве системы для тестирования взаимодействий аналитов с неподвижной фазой применяли набор подвижных фаз различной кислотности, содержащих 90 об.% ацетонитрила. Для оценки вклада ионного обмена в удерживание заряженных соединений при крайних рассматриваемых значениях рН проводили варьирование концентрации элюирующего иона.
Было установлено, что во всём диапазоне  подвижной фазы от 2.85 до 5.76 ( 5.5-9.2) у сорбента преобладали анионообменные свойства, которые были обеспечены влиянием четвертичных аминогрупп, сформированных в первом и втором функциональных слоях на поверхности матрицы. Это привело к низким факторам удерживания катиона тиамина, характеризующегося высокой гидрофильностью (log D = -4.20), во всех рассматриваемых условиях. Однако факторы удерживания и вклад ионного обмена для органических анионов значительно снижались с ростом рН, что, по-видимому, было вызвано увеличением степени диссоциации карбоксильных, остаточных силанольных и протонированных аминогрупп сорбента. При этом было отмечено уменьшение удерживания нейтральных аналитов, что, вероятно, было вызвано снижением толщины приповерхностного водного слоя неподвижной фазы, принимающего непосредственное участие в механизме распределения, и возможным изменением силы адсорбционных взаимодействий.
Для слабых кислот были получены неожиданные зависимости удерживания при варьировании состава подвижной фазы. Для бензойной кислоты, практически недиссоциированной при  элюента, равном 2.85, установлен высокий вклад ионного обмена – вплоть до 80% при 1.25 мМ концентрации элюирующего иона в подвижной фазе. В случае ксантина показан существенный рост факторов удерживания и вклада электростатических взаимодействий с увеличением рН элюента, что не согласовалось с величиной его , равной 7.60. Отмеченные наблюдения свидетельствовали в пользу применения водно-органической шкалы рН при работе в гидрофильном режиме хроматографии и учёта влияния ионного обмена на удерживание аналитов даже при низкой степени их диссоциации.
Таким образом, разработанный способ создания гиперразветвленного цвиттер-ионного функционального слоя на поверхности 3-аминопропилсиликагеля обеспечил получение неподвижной фазы с преобладающими анионообменными свойствами в рабочем диапазоне рН. Варьирование кислотности и концентрации буферного раствора подвижной фазы позволило подбирать условия эффективного и селективного разделения многокомпонентной смеси, содержащей вещества различной гидрофильности и заряда.
Analysis of the Efficacy of Erythromycin Cyclic 11,12-Carbonate Combined with Azithromycin in the Treatment of Severe Mycoplasma Pneumoniae Pneumonia in Children and its Effect on Cytokines
Authors: Ran Dong , Jie Li , Jiannan Wu , Wenjun Hu , Lulu Yan , Jing Le
Published: August 2024

Introduction: Mycoplasma Pneumoniae Pneumonia (MPP) is an inflammation of the lungs caused by Mycoplasma pneumoniae infection. Macrolide antibiotics are the therapeutic agents of choice for MPP. This study aimed to explore the efficacy of erythromycin cyclic 11,12-carbonate combined with azithromycin in treating children with severe Mycoplasma pneumoniae pneumonia (SMPP). Methods: 84 children with SMPP treated at Hubei Maternal and Child Health Hospital between February 2021 and December 2021 were randomly divided into two groups. The control group was treated with intravenous azithromycin and then changed to oral azithromycin. The experimental group was treated with intravenous azithromycin and then switched to oral erythromycin cyclic 11,12-carbonate. The clinical efficacy, symptom improvement, inflammatory levels, and cytokine levels before and after treatment were compared, and the occurrence of adverse reactions was recorded. Results: The overall effective rate of treatment in the experimental group was significantly higher than that in the control group (P<0.05). The time to the disappearance of clinical symptoms and length of hospitalization of the experimental group was significantly shorter than that of the control group (P<0.05). After treatment, inflammatory levels and cytokine levels of the experimental group were significantly lower than those of the control group (P<0.05). There was no difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Erythromycin cyclic 11,12-carbonate combined with azithromycin in the treatment of children with SMPP had significant efficacy, superior to azithromycin monotherapy, which could effectively improve immune function and clinical symptoms.
Immunofluorescence and microscopy_reformatted v1
Authors: Lam Isabel , Ndayisaba Alain , Khurana Vikram
Published: August 2024

Immunofluorescence and microscopy_reformatted
AAV Purification Protocol with Iodixanol Gradient v1
Authors: Marongiu Roberta
Published: August 2024

Protocol used in the Kaplitt and Marongiu labs to purify AAVs.
Automated immunodetection of proteinase-K-resistant Lewy Pathology in FFPE human colon tissue v1
Authors: Videlock Elizabeth
Published: August 2024

Automated detection of gut Lewy Pathology using Leica Bond RX processor based on Protocol F using Bond Polymer Refine Detection kit (Leica Biosystems,Cat#: DS9800). Adapted from "Method 5" as described in Beach TG et al., J Parkinsons Dis. 2016. Acknowledgments We are grateful to the Banner Sun Health Research Institute Brain and Body Donation Program of Sun City, Arizona, for the provision of human colon tissue and data. The Brain and Body Donation Program is supported by the National Institute of Neurological Disorders and Stroke (U24 NS072026 National Brain and Tissue Resource for Parkinsons Disease and Related Disorders), the National Institute on Aging (P30 AG19610 Arizona Alzheimers Disease Core Center), the Arizona Department of Health Services (contract 211002, Arizona Alzheimers Research Center), the Arizona Biomedical Research Commission (contracts 4001, 0011, 05-901 and 1001 to the Arizona Parkinsons Disease Consortium) and the Michael J. Fox Foundation for Parkinsons Research. We wish to acknowledge Yunfeng Li and the Translational Pathology Core Laboratory (TPCL) at UCLA for assistance with tissue processing, IHC staining, and scanning.
Pengaruh ROA dan ROE Terhadap Harga Saham
Authors: Narmaditya Bagus Shandy , Wahyono Hari , Li Zhenyu , Sakarji Siti Rosnita
Published: August 2024

This study aims to systematically review the future of economic education and identify the trends and implications for policy and practice. This study adopted bibliometric analysis using VOSviewer software. The findings indicate that there has been a substantial movement over the last two decades regarding the theme of economic education. The top three countries—United States, Germany, and Indonesia contribute to this theme, whilst Universitas Negeri Malang, the University of Nebraska, and the University of Richmond are the three highest organizations that contributed to this scope during this period. The visualization from VOSviewer illustrates that the theme of economic education is linked with various dimensions. The frequency occurrence of this theme is often associated with financial literacy, pedagogy, pluralism, higher education, active learning, financial education, home economics education, teaching economics, economic literacy, heterodox economics, and entrepreneurship. The findings provide implications for concerning studies in this theme with a focus in shaping graduate students.
Pelabelan skolem graceful pada graf (S_n,r)
Authors: Sedayu Angger , Purwanto Purwanto
Published: August 2024

Pelabelan pada suatu graph adalah pemetaan yang memetakan unsur-unsur graph yaitu himpunan titik, himpunan sisi, maupun himpunan titik dan sisi ke suatu bilangan asli dengan aturan tertentu. Pelabelan Skolem Graceful adalah fungsi injektif γ dari himpunan titik V ke himpunan bilangan {1,2,…,|V|} yang menginduksi fungsi bijektif γ' dari himpunan sisi E ke himpunan {1,2,…,|E|} dimana setiap sisi uv∈E dengan titik u,v∈V berlaku γ'(uv)=|γ(u)-γ(v)|.Pada skripsi ini ditunjukkan bahwa graf (S_n,r) mempunyai pelabelan skolem graceful untuk 2≤r≤5. Pembuktian dilakukan dengan mengkontruksi himpunan pelabelan titik dan pelabelan sisinya. Graf (S_n,r) adalah suatu graf yang dibangun dari graf bintang S_n sebanyak r, kemudian diberikan sebuah titik pusat c yang dihubungkan ke setiap titik pusat S_n dengan menambahkan sisi.Dari pembahasan diperoleh graf (S_n,r) untuk 2≤r≤5 mempunyai pelabelan skolem graceful. Pelabelan Skolem Graceful pada graf 〖(S〗_n,r),2≤r≤5 dikerjakan dengan melabeli titik terlebih dahulu, dan dilanjutkan dengan melabeli sisi. Lebih lanjut pembahasan ini dapat dibuat aplikasi khusus untuk memeriksa apakah suatu graf dapat dilabeli secara skolem graceful untuk graf 〖(S〗_n,r) untuk r lebih tinggi.
Program untuk permasalahan multiple trip vehicle routing problem (MTVRP) menggunakan algoritma memetic pada proses pendistribusian
Authors: Nuswantari Ike Putri , Madja Mimiep Setyowati
Published: August 2024

In everyday life almost all problems require the help of mathematics, one of them on the transportation or on the distribution prosess. Multiple Trip Vehicle Routing Problem (MTVRP) is one of the problems related to the transportation or distribution prosess. Multiple Trip Vehicle Routing Problem (MTVRP) is defined as the problem of the Vehicle Routing Problem (VRP) with the expansion and the addition of multiple trips on the each vehicle when it distributes goods and the time window of customer service. One algorithm to solve the Multiple Trip Vehicle Routing Problem (MTVRP) is memetic algorithms. Memetic algorithm is a combination of genetic algorithm and local search procedures that intensify the search. Memetic algorithms procedures are: initialization process, evaluation process, selection, crossover process, mutation process, repair process, local search, vehicle allocation, and the best route is formed. To facilitate the search for the solution of the Multiple Trip Vehicle Routing Problem (MTVRP) especially at the time had to submit to many customers, memetic algorithms implemented in the language programming Borland Delphi. By using an program application be made, produced together with the results obtained manually route 0 – 1 – 3 – 4 – 0 – 5 – 2 – 0 with a travel time "1.1675" hours and uses a vehicle. This program is designed applications up to 50 points in the Multiple Trip Vehicle Routing Problem (MTVRP) using memetic algorithms, which is already in trials with 11 points, 22 points, and 50 points in attachment. So that the application program can be used to solve the Multiple Trip Vehicle Routing Problem (MTVRP) using memetic algorithms on the transportation or on the distribution prosess.
Pengembangan model antrian multi channel single phase berbasis distribusi burr (Studi Kasus di PT Pos Indonesia (Persero) Malang)
Authors: Rahmawati Dwi , Permadi Hendro
Published: August 2024

Penelitian ini bertujuan untuk mengetahui model antrian yang representatif dan menghitung ukuran performansi pada antrian pelanggan di PT Pos Indonesia (Persero) Malang. Data yang digunakan adalah data jumlah kedatangan pelanggan, data waktu antar kedatangan pelanggan dan data waktu pelayanan pelanggan. Penelitian ini dilakukan di PT Pos Indonesia (Persero) Malang pada server 5 sampai 10. Data penelitian ini diambil pada tanggal 20 Juni 2015. Tanggal 20 merupakan tanggal jatuh tempo untuk pembayaran rekening listrik, rekening PDAM dan rekening telepon sehingga pada tanggal tersebut sering terjadi antrian. Berdasarkan hasil analisis diperoleh model antrian G/G/6: FCFS/∞/∞, dengan G merupakan simbol pengganti untuk Distribusi Burr. Hasil ukuran performansi diperoleh tingkat kegunaan fasilitas (ρ) sebesar 92,4%, rata-rata pelanggan dalam antrian 〖(L〗_q) adalah 4 orang, rata-rata pelanggan dalam sistem 〖(L〗_s) adalah 10 orang, waktu rata-rata pelanggan menunggu dalam antrian 〖(W〗_q) adalah 2.43 menit dan waktu rata-rata pelanggan menunggu dalam sistem 〖(W〗_s) adalah 5.8 menit.
Empowering Virtual Calligraphy Expo as a Solution during a Pandemic
Authors: Dian Cita Sari  , Makmur Harun  , Mohd Kasturi Nor Bin Abd Aziz
Published: August 2024

This study aims to study how calligraphers respond to the pandemic. This issue is considered important, because all activities involving large numbers of people are postponed. Exhibitions have a broad role for artists and calligraphers. In order to be widely used, the treasures of exhibition innovations need to be made public. Publication of exhibition innovations is one of the efforts to reach a wider community. One of the outreach efforts that can be done during the current pandemic is a calligraphy virtual exhibition. Some things that need to be analyzed are the process of calligraphy virtual exhibition activities; content coverage; and the factors that influence visits to the Exhibition's official website. Through a case study approach, this study attempts to describe some of the things analyzed. The results of the research show that the calligraphy virtual exhibition process can be carried out systematically and sustainably and is even more acceptable in accordance with the will of the times; content coverage is quite diverse; and the factors that influence visits to the Archive's official website can be identified.
الخطُّ العربيُّ من الأساطيرِ الغَيْبِيَّةِ إلى الجُهُودِ البَشَرِيَّة
Authors: الأستاذ الدكتور مصطفى محمد رزق السواحلي
Published: August 2024

No doubt, that Allah has chosen Arabic calligraphy to write the words of the Holy Qur’an, and gave it magnificence and beauty that was not available to any other calligraphy. So it with its exquisite geometric shapes paints some unlimited beautiful images, even it became an independent art. Arabs were satisfied with it for obscene images and nude statues, and this geometric formation became an aesthetic feature that gave Islamic civilization a special character throughout the ages. This transcendent beauty led a group of scholars to say that it descended from the divine in this wonderful image that is beyond the human capacity, and Arabic heritage books have been loaded with dozens of narrations in this field .This is what this research attempts to achieve, in order to differentiate between what is the metaphysical that needs a definitive text of proof and significance, and what is the human as a product of the cumulative efforts of the experiences of scientists and creators throughout the ages, which requires a rational, moderate position on the issue of the unseen generally, then to present a number of those narrations scattered in the wombs of the books of Arab heritage, and criticize them as a narration and knowledge. Then to mention those who borrowed Arabic calligraphy from the neighboring nations before Islam, and who developed it after Islam, until it became an Islamic industry par excellence, through the descriptive analytical method. In the end the research concluded with a number of results, the most important of them are: Belief in the unseen is a religious duty, provided that there is a valid evidence from the authentic revelation, which is lacking in the narrations that are filled inside the books of Arab heritage that attribute the development of Arabic calligraphy to a group of those who passed away, starting with Adam, peace be upon him. Some scholars have escaped from confronting this problem to the saying of revelation, which has no evidence for it, if it was by inspiration; there was no difference or development in it, as it did not happen in the Holy Qur’an. Most realistic narrations indicate that the Arabs borrowed their calligraphy from the neighboring nations, especially from the Nabataean script in the Anbar region. The bond between the writing and civilization is an inseparable bond, which is what was achieved for Arabs after the appearance of Islam, which makes us to say: It is an Islamic industry par excellence, and the follow-up of the efforts of Arab scholars in the field of developing Arabic calligraphy confirms that the calligraphy is a human industry, developed by the scholars who spent their ages in serving the sciences and arts in Arabic language.
نموذج المواد التعليمية للخط العربي في المدرسة الإبتدائية بمؤسسة معهد النور الكشاف الإسلامي بيكاسي
Authors: Siti Jubaidah  , Maulidiana Nur Alfi Syahrin
Published: August 2024

This study aims to design a model of Arabic Calligraphy in Islamic College Foundation Elementary School El-Nur El-Kasysyaf based on a student needs analysis. This development and research uses the R&D method of R&D in the manner of Dick and Carrie model with ADDIE code. And the data collection techniques used through participatory observation, structured interview, unstructured interview and questionnaires. Arabic calligraphy material model consists of 3 themes in it, Single Letter Writing Rules, Rules for Writing Connecting Letters, Change the order of single letters to words and Otherwise. This material model also include learning books and videos as complementary material and explanation related to other write activities needed to increase innovation in increasing students interest in understanding Arabic calligraphy. The first reviewer's response for the Arabic calligraphy material model got a score of 85%, from the second reviewer got a score of 94% with the "Very Feasible" score category. The response from students reached a score of 88% in the "Very Feasible" category.
تعليم خط النسخ العربي باستخدام طريقة العرض التوضيحي لتحسين كتابة القرآن الكريم في معهد سنان أمبيل العالي جامعة مولانا مالك إبراهيم الإسلامية الحكومية مالانج
Authors: Muhammad Farih
Published: August 2024

Teaching Arabic calligraphy to write the Noble Qur’an among middle class students in the Holy Qur’an education program from one of the educational programs at the sunan Ampel Higher Institute, Maulana Malik Ebrahim State Islamic University Malang in 2022. Teaching Arabic calligraphy can have a great impact on writing the Noble Qur’an. The Arabic Naskh script is taught using the display method and its effect to improve the writing of the Noble Qur’an among students of the middle class E in the Holy Quran Teaching Program at the sunan ampel Higher Institute, Maulana Malik Ibrahim State Islamic University Malang in 2022. To obtain these results, the researcher searches Classroom Action or procedural research uses The teacher is a researcher, so he is responsible for the research.
The results of the first round show the maximum results, the data partly an increase in education results from the first encounter data to the second by 4.00 points from the lowest score from 68.2857143 to 72.2857143 However, after cumulative analysis of the average value of the first session from the first encounter and the second, the two highest score 77, and the lowest Score 59, average class value 70.5789474, KKM 65 achievement with a maximum of 27 people (77%) of the total student population up to 35 people, KKM 65 achievement with a minimum of 8 people (23%), and in the second round with 5.00 points of average class value 75.83 to 82.8. While the results of the cumulative analysis of the average value of the second session from the third and fourth meetings, the highest score was 88, the lowest score was 72.5, the average class value was 79.3142857, and the achievement of KKM 65 up to 35 people (100%) out of a total of 35 students. These data show that the research success indicators have been achieved (well's teaching) and will be consistent with the previously defined learning success indicators.
Factores asociados a la adherencia terapéutica de personas con hipertensión arterial en atención primaria
Authors: Andrade-Méndez Brayant , Troche-Gutiérrez Ingrid Yolercy , Torres-Muñoz Laura Daniela
Published: August 2024

Introducción: la hipertensión arterial es un problema de salud pública que afecta principalmente a la población adulta, que, aunado a una baja adherencia terapéutica, limita el control de la patología y logro de objetivos terapéuticos.  Objetivo: determinar la prevalencia de la adherencia terapéutica de personas con hipertensión arterial y la relación con factores de riesgo conductuales y metabólicos en atención primaria de la ciudad de Neiva, Colombia. Materiales y métodos: estudio analítico de corte transversal, con una muestra de 335 adultos hipertensos seleccionados de manera aleatoria, asistentes a un programa de riesgo cardiovascular.   Se evaluaron factores de riesgo conductuales y metabólicos, mediciones antropométricas, clínicas y el nivel de adherencia terapéutica. Para el análisis estadístico se usó Stata 15, aplicando medidas de tendencia central y de asociación. Resultados:  la adherencia terapéutica fue 39,4% y se encontró asociación estadísticamente significativa con la adultez (OR: 2,46; IC 95%: 1,49 - 4,05), escolaridad (OR: 3,14; IC 95%: 1,82 - 5,42), tomar 3 o menos medicamentos (OR: 2,09; IC 95%: 1,27 - 3,43) y con objetivos terapéuticos como IMC normal, normotensión y  normoglicemia. Conclusiones: la prevalencia de la adherencia terapéutica fue baja, similar a la evidenciada en otros contextos de pacientes con patologías crónicas, asociado a factores comportamentales y metabólicos.
El OVA como estrategia para mejorar la comprensión lectora en estudiantes de francés
Authors: Astaiza-Samboni Mary Elizabeth , López-Molina Maricela
Published: August 2024

El objetivo de este estudio es evaluar la efectividad de un objeto virtual de aprendizaje (OVA) en la mejora de la comprensión lectora en francés entre estudiantes de tercer semestre de la Licenciatura en Lenguas Modernas en la Universidad del Cauca. Se implementó un diseño preexperimental con un grupo de 26 estudiantes, a quienes se les aplicó un pretest y un postest para medir la comprensión lectora antes y después de la intervención con el OVA. El análisis de los datos se realizó mediante técnicas estadísticas descriptivas. Los resultados revelaron una mejora significativa en la comprensión lectora, con un incremento del 34% en las respuestas correctas a nivel literal y del 41% a nivel inferencial. Estos hallazgos sugieren que el uso del OVA es una estrategia eficaz para mejorar la comprensión lectora en francés. Se recomienda su implementación en otros niveles académicos y su adaptación a la enseñanza de otros idiomas.
Ethos de competitividad organizacional en salud: impulsores para las aseguradoras en salud del régimen contributivo
Authors: Sanabria-Rangel Pedro Emilio , Szőcs-Martínez Francisco José
Published: August 2024

La investigación se propuso establecer sistémicamente los principales impulsores (drivers) que pueden desarrollar la competitividad de las organizaciones de salud, concretamente para las aseguradoras en salud del régimen contributivo (EPS´s) en el contexto colombiano. El estudio fue interpretativo, cualitativo y descriptivo-exploratorio, estudiando documentos que mostraran los posibles impulsores de la competitividad, adaptándolos a la ‘industria’ de la salud, con un análisis específico. Se identificaron aquellos que, conjuntamente y dentro un comportamiento competitivo-organizacional, podrían ser sus factores diferenciales y competitivos en tres dimensiones o categorías (organizacional, estrategia y resultados) y atravesados por tres niveles de análisis (macro, meso y micro). Esto puede ser útil para aportar al desarrollo de la capacidad competitiva de las EPS nacionales, como plataforma de discusión para la política pública y una posible reforma respecto al sistema de salud y para estudiar la competitividad de este sector y sus organizaciones hacia el futuro.
Evaluación in vitro de adaptación marginal en carillas disilicato de litio: técnica inyectada vs maquinada
Authors: Calapuja-Chura José Luis
Published: August 2024

El disilicato de litio es una cerámica vitreada que contribuye para la restauración de los dientes. Para ello, existen dos técnicas por lo que son empleadas: técnica de inyección por calor y CAD/CAM. Objetivo: Evaluar la comparación in vitro de la técnica inyectada vs maquinada de la adaptación marginal en carillas de disilicato de litio en troqueles de dientes anteriores. Material y métodos: Se aplicaron las pruebas estadísticas de Shapiro-Wilk y la T-Student para la comparación de las dos técnicas. Resultados: Se evidenció que en la adaptación marginal, en la técnica maquinaria e inyectada, la adaptación cervical evidencia una diferencia significativa de p = 0.000; asimismo, la adaptación distal presentó diferencia significativa de p = 0.002. Por otra parte, en la adaptación mesial y palatina no se evidenciaron diferencias significativas (p= 0.112; 0.817) respectivamente. Conclusiones: No se registra una diferencia significativa entre la media de la adaptación marginal de las carillas de disilicato de litio, sin embargo, esta presentó una mejor adaptación en las carillas elaboradas con técnica inyectada a comparación de la técnica maquinada.
STUDY ON SELF-DIFFUSION IN ALLOY AuCuSi WITH FCC STRUCTURE: DEPENDENCE ON TEMPERATURE, PRESSURE, CONCENTRATION OF SUBSTITUTIONAL ATOMS, CONCENTRATION OF INTERSTITIAL ATOMS AND STRAIN
Authors: Quang Hoc Nguyen , Nu Binh Minh Tran , Nghiem Ngoc Lan Truong , Thi Bich Lam Nguyen , Hong Viet Le , Thi To Giang Dam
Published: August 2024

This article presents a self-diffusion theory, including analytical expressions for activation energy, pre-exponential factor, and self-diffusion coefficient, dependent on temperature, pressure, the concentration of substitutional atoms, the concentration of interstitial atoms, and strain for substitutional and interstitial ternary alloys with the FCC structure, based on the statistical moment method (SMM). The theoretical results are applied to numerical calculations for the AuCuSi alloy. The SMM numerical results for AuCuSi are compared with those for AuSi, AuCu, and Au. The variation of self-diffusion quantities with temperature and strain in AuCuSi follows the same patterns as in AuCu, AuSi, and Au. The variation with the interstitial atom concentration in AuCuSi follows the same pattern as in AuSi, while the variation with the substitutional atom concentration follows the same pattern as in AuCu. The SMM numerical results for Au's self-diffusion quantities agree well with experimental data and other calculation results. Other SMM numerical results for self-diffusion quantities are novel and predict future experimental outcomes.
SYNTHESIS AND STRUCTURE OF SOME 8-METHOXY-2-ARYLQUINOLIN-7-OL DERIVATIVES FROM VANILLIN
Authors: Minh Luong Truong
Published: August 2024

The key compound, 4-hydroxy-3-methoxy-2-nitrobenzaldehyde (3), was synthesized from vanillin by esterification, nitration, and hydrolysis.  The aldol condensation reaction of compound 3 was performed with aryl methyl ketones to obtain two chalcones 4a and 4b. The reduction reactions of these chalcones 4a and 4b were performed using SnCl2 in HCl to obtain two 8-methoxy-2-arylquinolin-7-ol derivatives 5a and 5b. The structures of the two quinoline derivatives were confirmed by 1H-NMR, 13C-NMR spectroscopic methods and MS and HRMS spectrometry.
Bioprospecting the Anticancer Efficacy of Garcinia anomala from North-East India in Ovarian Cancer Cells – An In Vitro Study
Authors: Pillai Gautami , Kar Ashish , Kumar Satyanshu , Shah Zeel , Pawar Rajvi , Bhurawala Nouman , Mahapatra Ananya , Nampoothiri Laxmipriya
Published: August 2024

Background: Ovarian cancer is a type of gynaecological cancer with a worldwide prevalence affecting women aged above 50. Despite several advances made in chemotherapy and surgery, the average time of clinical exemption is approximately two years, and the 5-year survival rate is 45%. But even after survival, they have long-term side effects. So, there is an urgent need for natural anticancer drugs. In this context, Garcinia spp. is one such plant that is explored for its anticancer properties. However, the endemic species Garcinia anomala from North-East India has not been studied for anticancer efficacy. Thereby present study aimed to understand the anticancer efficacy of hexane and methanol extracts of Garcinia anomola short mamilla plant available in the North-East region of India with a major emphasis on antioxidant potential. Further, the best extract with higher antioxidant activity was used to evaluate the anticancer potential through modulation of redox status. Methods: Total phenolic content in extract samples was determined by the Folin-Ciocalteu method. The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity assay was used to assess the antioxidant activities of extracts. For in vitro evaluation of the anticancer potential of the extract, ovarian teratocarcinoma PA1 cells were used as a model to study the dose-dependent effect of the extract. Various assays, such as wound healing assay and transcriptional analysis of genes, such as Bcl-2, PCNA, and TP53, were performed. For the redox parameter, DCFDA (2’,7’-Dichlorofluoroscin Diacetate) assay was used. Results: The results showed that Garcinia anomola methanol extract (EB) exhibited higher antioxidant activity in comparison to the hexane extract (EA). A cytotoxicity assay was performed to find the effective IC50. From this assay, the effective dose concentration confirmed for EA was 40 µg/mL, EB was 20 µg/mL, and the time point selected was 24 hrs. As the IC50 for EB was less than EA, EB was chosen for further assays. From the wound healing assay, the migration rate obtained was 0.967±0.041 µm/hr. The methanol extract was found to affect key cell cycle checkpoint genes at the transcript level. Conclusion: These results indicate that the anticancer potential is mediated through the modulation of antioxidant status. Thus, Garcinia anomala short mamilla extract from northeast India has good efficacy as an anticancer agent, which can be considered as a future potent drug candidate for ovarian cancer.
Predicting Tourist Arrivals: A Google Trends-Based Model for Destination Management
Authors: Georgieva-Trifonova Tsvetanka , Mancheva-Ali Olga
Published: August 2024

In this paper, a review of the scientific literature on the importance and knowledge of the tourist destination for the formation of a correct strategy for its development and promotion is made. The possibility of managing the tourist destination by modeling with Google Trends data is represented. A review of studies using the mentioned tool in the field of tourism is conducted. The potential benefits of using Google Trends data on searches for a city as a keyword in combination with archival data are summarized. The possibilities for modeling the visits of tourists using data from Google Trends are investigated, as a result of which a model is built by applying polynomial regression to predict the overnight stays of foreign citizens in the city of Veliko Tarnovo based on archival data from the National Statistical Institute and Google Trends data. Through data analytics with Google Trends, it is concluded that key value is created for the external and internal environment, influencing the destination. The data creates conditions for the development of management strategies for attracting tourists based on primary and secondary data for analysis. The application of the received data sets through data analysis are also important for tourism organizations and institutional bodies in tourism (macro- and meso-level). The resulting analysis affects issues related to the management and marketing of the destination, and on the other hand, it directly affects the segmentation of the market and the distribution of products and services to the end user (micro level).