bluuebunny/crossref_metadata_2025 huggingface dataset:
PROSPECTS FOR THE DEVELOPMENT OF FINANCIAL MARKETPLACES
Authors: Львова М.И. , Каменщик В.М.
Published: July 2024

Технологическое развитие IT-решений в современной эконо- мической ситуации в отрасли финансовых продуктов приводит к появлению платформенных сервисов, в том числе финансовых маркетплейсов. Данное новое направление является источником по созданию новой конкурентной среди финансово-кредитных институтов. Целью исследования является изучение перспектив развития финансо- вых маркетплейсов в рамках российского экономического пространства. В основе методов исследования находятся сравнительный анализ тради- ционных вариантов предоставления финансовых услуг и варианта приме- нения финансовых маркетплейсов, как одного из примеров платформенных сервисов. Также применяется библиометрический метод для изучения про- работанности вопроса в рамках мировой практики, а также в разрезе науч- ных работ отечественных авторов. Методы дедукции и синтеза использован в рамках исследования для выявления и объединения ключевых качеств и свойств, которыми обладает платформенное решение, а также проводится обоснование актуальности и целесообразности его применения. В рамках исследования произведен сравнительный анализ возможно- стей и свойств цифровых платформ. Также проводится анализ потенциаль- ных преимуществ, которые могут быть предоставлены клиентам платформ в рамках их использования. Дополнительное проводится рассмотрения ри- сков, связанных с внедрением финансовых маркетплейсов, а также приво- дятся способы их митигации. В рамках выводов исследования выделяются существенные перспекти- вы для финансовых институтов и их клиентов в рамках перехода к модели взаимодействия посредством финансовых маркетплейсов. Кроме того, авто- ры выделяют в качестве высоких перспективы по масштабированию данных платформ из формата российских в формат международных за счет их вы- хода на рынки ближайших стран в обозримом будущем. Научная новизна обуславливается малой проработанностью тематики в научных работах, а также высоким потенциалом положительных эффектов, как для финансовых институтов, так и для клиентов сервисов.
REGIONAL IMBALANCES AS A THREAT NATIONAL SECURITY OF THE STATE
Authors: Луговая В.С. , Cонмезсой М.С. , Корнекова С.Ю.
Published: July 2024

Помимо политических волнений, происходящих на мировой арене и способствующих дестабилизации уклада во многих странах, Россий- ская Федерация сталкивается и с внутренними угрозами национальной без- опасности. Они порождены политикой радикальных экономических реформ последних десятилетий, «шоковой терапией» и ростом межрегиональных диспропорций. Как показывает мировой опыт, именно последние нередко приводят к глубоким социальным кризисам и потрясениям. Заранее обнару- жить наличие таких проблем достаточно сложно, однако именно их предот- вращение является неотъемлемым звеном в обеспечении и поддержании стабильности в любой стране. В данной работе проведено эконометрическое исследование, выявляющее, как региональные диспропорции ослабевают территориальную целостность России. Для определения масштабов реги- ональных диспропорций были использованы такие методические приемы, как индекс FSI («индекс хрупких государств»), тест Колмогорова-Смирнова, метод Бокса-Кокса, ранговая корреляция Спирмена. В качестве предмета ис- следования были выбраны 46 субъектов Российской Федерации, по которым был проведен сбор данных в период с 2006 по 2021 год, после чего было вы- делено 18 потенциальных критериев, которые влияют на формирование ре- гиональных диспропорций. В ходе исследования было построено и описано 9 регрессионных моделей, которые отражают динамику на уровне государства в целом, а также на уровне федеральных округов. Результаты, которые были получены по всем 9 объектам, показывают наличие значительного разрыва между регионами в сфере демографии. Другими факторами, влияющими на формирование региональных диспропорций, являются продолжительность жизни, индексы человеческого развития и качества жизни.
INFORMATION TECHNOLOGIES IN THE FIELD OF ACCOUNTING
Authors: Шемеева З.А. , Рабаданова Ж.Б.
Published: July 2024

Данная статья посвящена актуальным вопросам автомати- зации данных бухгалтерского учета, поскольку выбор автоматизированной программы напрямую влияет на качество учетных данных и бухгалтерской отчетности. Одной из важнейших особенностей глобализации и комплексно- го развития экономики является применение информационных технологий и собранной информации в других формах производства в целях улучшения её эффективности. Автоматизированная информационная система бухгал- терского учёта – это система, использующая специальные методы обработ- ки данных и использующая комплекс вычислительных, коммуникационных и других технических средств для получения и предоставления информации, необходимой бухгалтерам для принятия управленческих решений и выпол- нения учётной и финансовой работы, в целях автоматизации учётный про- цесс. В последнее время стремительно развиваются цифровые технологии в ведении бухгалтерского учёта. Весь процесс учёта уже не представляется без использования автоматизированных информационных систем. Ввиду чего, главная задача при составлении бухгалтерской отчётности - это авто- матизация процессов учёта и объединение их с последними тенденциями в информационном мире. В работе раскрываются преимущества и недостатки современных про- граммных продуктов в области бухгалтерского и налогового учета. Авто- матизированный бухгалтерский учёт носит множество преимуществ перед традиционным способом ведения бухгалтерского учёта. Компьютеризация бухгалтерской работы дает возможность повысить качество труда работни- ков бухгалтерии, значительно уменьшить влияние человеческого фактора, увеличить скорость формирования и представления отчётности, организа- ции документооборота, отслеживание договоров. Кроме того, автором исследованы перспективы внедрения информацион- ных технологий в организации, ведении, хранении и обработке учетной ин- формации экономического субъекта.
Assessing the domain-based local pair natural orbital (DLPNO) approximation for non-covalent interactions in sizable supramolecular complexes
Authors: Gray Montgomery , Herbert John
Published: July 2024

The titular DLPNO approximation is the most widely used method for extending correlated wave function models to large molecular systems, yet its fidelity for intermolecular interaction energies in large supramolecular complexes has not been thoroughly vetted. Non-covalent interactions are sensitive to tails of the electron density and involve nonlocal dispersion that is discarded or approximated if the screening of pair natural orbitals (PNOs) is too aggressive. Meanwhile, the accuracy of the DLPNO approximation is known to deteriorate as molecular size increases. Here, we test the DLPNO approximation at the level of second-order Moeller-Plesset perturbation theory (MP2) and coupled-cluster theory with singles, doubles, and perturbative triples [CCSD(T)], for a variety of large supramolecular complexes. DLPNO-MP2 interaction energies are within 3% of canonical values for small dimers with $\lesssim 10$ heavy atoms, but for larger systems the DLPNO approximation is often quite poor unless the results are extrapolated to the canonical limit, where the threshold for discarding PNOs is taken to zero. Counterpoise correction proves to be essential in reducing errors with respect to canonical results. For a sequence of nanoscale graphene dimers up to (C96H24)2, extrapolated DLPNO-MP2 interaction energies agree with canonical values to within 1%, independent of system size, provided that the basis set does not contain diffuse functions, as these cause the DLPNO approximation to behave erratically, such that results cannot be extrapolated in a meaningful way. DLPNO-CCSD(T) calculations are typically performed using looser PNO thresholds as compared to DLPNO-MP2, but this significantly impacts the accuracy for large supramolecular complexes. Standard DLPNO-CCSD(T) settings afford errors of 2-6 kcal/mol for dimers involving coronene (C24H12) and circumcoronene (C54H18), even at the DLPNO-CCSD(T1) level.
CLC-DB: an online open-source database of chiral ligands and catalysts
Authors: Yu Gufeng , Yu Kaiwen , Wang Xi , Huo Xiaohong , Yang Yang
Published: July 2024

As an important research area in organic chemistry, asymmetric catalysis has contributed greatly to the development of chemistry and other fields, and chiral ligands/catalysts are the core research content of it. However, traditional experimental methods still have some limitations, and machine learning (ML)-based computational methods suffer from the lack of sufficient and accurate data resources about chiral ligands/catalysts. To overcome this challenge, we develop the Chiral Ligand and Catalyst Database (CLC-DB). To our best knowledge, CLC-DB is the first open-source and largest professional database for chiral ligands/catalysts, containing 1861 molecules of several basic chiral types that belong to 32 different chiral ligand/catalyst types. A total of 19 items of information are included for each data record, including the 2D and 3D chemical structure, ligand/catalyst category, chiral type, chemical and physical properties, artificial intelligence (AI) generated description, etc. Each molecular data is linked with authoritative chemical databases and validated by chemical experts. CLC-DB is a user-friendly database that supports two quick search methods and batch search. In addition, CLC-DB provides an efficient online molecular clustering tool for ML computational analyses. CLC-DB is accessible at https://compbio.sjtu.edu.cn/services/clc-db, and all the data can be downloaded for free.
Unravelling the Structure and Dynamics of Ac-PHF6-NH2 Tau Segment Oligomers
Authors: Stroganova Iuliia , Toprakcioglu Zenon , Willenberg Hannah , Knowles Tuomas , Rijs Anouk
Published: July 2024

The aggregation of the proteins tau and amyloid-β is a salient feature of Alzheimer’s disease, the most common form of neurodegenerative disorders. Upon aggregation, proteins transition from their soluble, monomeric, and functional state into insoluble, fibrillar deposits through a complex process involving a variety of intermediate species of differ-ent morphologies, including monomers, toxic oligomers, and insoluble fibrils. To control and direct peptide aggrega-tion, a complete characterization of all species present and an understanding of the molecular processes along the aggregation pathway are essential. However, this is extremely challenging due to the transient nature of oligomers and the complexity of the reaction networks. Therefore, we have employed a combined approach that allows us to probe the structure and kinetics of the emergence of oligomeric species, following them over time as they form fibrillar structures. Targeting the tau protein peptide segment Ac-PHF6-NH2, which is crucial for the aggregation of the full protein, soft nano-electrospray ionization combined with ion mobility mass spectrometry has been employed to study the kinetics of heparin-induced intact oligomer formation. The formed oligomers are identified and characterized using high-resolution ion mobility mass spectrometry, demonstrating that the addition of heparin does not alter the structure of the oligomeric species. The kinetics of fibril formation is monitored through a Thioflavin T fluorescence assay. Global fitting of the kinetic data indicates that secondary nucleation plays a key role in the aggregation of the Ac-PHF6-NH2 tau segment, while the primary nucleation rate is greatly accelerated by heparin.
Multi-edge X-ray Absorption Spectroscopic Evidence for Sulphur-based Redox in [4Fe-4S] Molecular Clusters
Authors: Szilagyi Robert
Published: July 2024

Central to the dogma of Fe–S World Hypothesis for the Emergence of Biosphere is the transition from non-living Fe–S geochemistry to the molecular Fe–S biochemistry. While often assumed this being a trivial and spontaneous process; however, the chemical reality is a critical discontinuity of oxidation states of ferrous iron-based minerals and nanoparticles in low temperature hydrothermal environments and ferric iron-based prosthetic groups in metalloproteins. A recent ingenious synthetic effort enabled the access of the first four-electron transfer-series in [4Fe-4S] molecular cluster with the same aromatic thiolate ligand environment. This discovery opened up the possibility to probe a range of [4Fe-4S] cubanes from the geological all ferrous to the hypothetical all ferric cluster along with each intermediate oxidation state. Multi-edge X-ray absorption spectroscopic (meXAS) approach provided us with the insights to put forward the exclusive sulphur-based redox chemistry with only minor perturbations to the Fe centres. The meXAS results unambiguously prove that the Fe ions in the molecular cubanes remain essentially the same as in the mackinawite-like nanoparticles (n(FeS)(aq), 𝑛 < 150) formed in the precipitation reaction of Fe2+(aq) and HS–(aq) ions under ambient aqueous conditions. Furthermore, the non- innocent redox chemistry of [4Fe-4S] clusters underscores the intimate relationship between the Fe and S ions that give rise to the concept of chimera of chemical elements - as the building block of Fe–S clusters and nanoparticles - with tantalizing chemical properties that neither of its components can manifest.
MolNetInvert: A Tool for Creating Metadata Based Molecular Networks and Their Applications in Large Microbial Datasets
Authors: Christiansen Johan V. , Jarmusch Scott A. , Vertot Manca , Andersen Aaron J.C.
Published: July 2024

Untargeted mass spectrometry-based metabolomics, crucial in diverse research areas such as clinical diagnostics and chemical ecology, often encounters the challenge of interpreting complex datasets with thousands of unique, low-annotation-rate features. Advancements in MS2-based molecular networking, particularly Feature-Based Molecular Networking and its offshoots, have improved data deconvolution and annotation. Although this is the case, these approaches often result in networks with numerous singletons, complicating interpretation when extended metadata is incorporated. Herein, we introduce Metadata-Based Molecular Networks (MBMN), a new approach to visualizing complex untargeted metabolomics datasets that enhances the interpretability of molecular networks in untargeted metabolomics, as well as MolNetInvert, an open-source GUI tool for producing these new networks. MolNetInvert simplifies network visualization by collapsing clusters into single nodes and reorganizes the networks into metadata centric networks. Overall, MBMN produces new networks based on selected metadata, creating new edges between metadata-linked nodes. Its utility is demonstrated through three case studies: 1) a co-culture analysis of metabolite production in fungal strains, 2) an investigation of secondary metabolism in black Aspergilli species using a public dataset, and 3) a comparative study of ant fungal gardens and trash piles. These applications underscore the effectiveness of MBMN’s in clarifying data analysis in mass spectrometry-based metabolomics networking, showcasing its potential in various research fields dealing with complex datasets.
Colloidal dispersions of cobalt ferrite nanoparticles in EMIM TFSI, propylenecarbonate and their mixtures
Authors: Guerra Ana Alice , Gomide Guilherme , Ibrahim Sameh , Burckel Pierre , Coppola Priscilla , Depeyrot Jérôme , Perzynski Régine , Peyre Véronique , Papovic Snezana , Vranes Milan , DUBOIS Emmanuelle , Campos Alex Fabiano
Published: July 2024

Liquid thermocells are promising devices for the recovery of low-grade waste heat and its conversion into electricity. The present study proposes dispersing charged magnetic nanoparticles in liquids to improve thermoelectric conversion, due to their thermo-diffusive and magnetic properties. Core-shell cobalt ferrite@maghemite nanoparticles (NPs) of various sizes with three different kinds of coatings are tested for dispersion in EMIM TFSI (ethyl-methylimidazolium bistriflimide), an ionic liquid (IL) of high electrical conductivity. Among the tested ligands, PAC6MIM+- (1-(6-hexylphosphonate) 3-methyl imidazolium bromide) emerges as the most efficient due to its phosphonic group. This ligand leads to dispersions of aggregates of a few dozen NPs in water and a few NPs in EMIM TFSI. For improving both the viscosity and the electrical conductivity, dispersions in binary mixtures of propylene carbonate (PC), a polar medium, and EMIM-TFSI are further investigated with the sample based on NPs of around 9 nm diameter. Through a pumping and heating procedure, stable dispersions are obtained with a subsequent reduction of the size of the NP aggregates, down to 1 to 2 NPs in EMIM TFSI and a few NPs in PC and their binary mixtures. The mixture with an IL mole fraction around 0.2-0.3 and maximal electrical conductivity is a promising candidate for further thermoelectric investigations.
On the Formation of a Cathode Electrolyte Interphase on High Voltage Li-ion Cathodes
Authors: Misiewicz Casimir , Edström Kristina , Berg Erik J.
Published: July 2024

The spinel oxide LiNi0.5Mn1.5O4 (LNMO) currently competes to replace the conventional layered transition metal oxide active material in Li-ion batteries. The high average operating potential (4.70 V vs. Li+/Li) challenges the stability of the electrolyte, which in turn compromises the lifetime of the Li-ion cell. Online electrochemical mass spectrometry (OEMS) is herein implemented to study the degradation processes occurring at the cathode surface. Gases continuously evolve across subsequent cycles as a result of electrolyte oxidation, a process that is found to be only potential-activated and independent of electrode surface composition. The subsequent formation of protic species autocatalyzes electrolyte salt degradation, which in turn triggers the corrosion of active material, current collector, and conductive carbons. The effectiveness of several well-known electrolyte additives, previously claimed to act as cathode electrolyte interphase (CEI) formers, were explored revealing the efficacy of phosphorus-based additives. Our study provides a rapid and quantifiable approach to tackle the major challenge of high voltage cathode materials, namely its stabilisation towards the electrolyte, and how to identify and develop an efficient CEI.
Controlled Release Lercanidipine Tablets: A Study on Formulation and Evaluation by Wet Granulation
Authors: A Sujana , K Durga Prasad , Talluri Sarada Mrinalini
Published: July 2024

Lercanidipine blocks the entry of extracellular calcium into vascular and cardiac muscle cells, preventing myocardial smooth muscle contraction due to decreased intracellular calcium. This results in the dilation of coronary and systemic arteries, reducing blood pressure. This study aimed to develop and evaluate lercanidipine controlled-release tablets for oral administration using polymers like HPMC K 100M, sodium alginate, and guar gum. Lercanidipine, polymers, and diluents were sieved and mixed for 10 minutes. Granules were formed using isopropyl alcohol, dried at 60°C for one hour, and sieved. The granules were lubricated with colloidal silicon dioxide (Aerosil-200) and magnesium stearate, blended for 5 minutes, and compressed using a rotary machine (average weight: 500 mg; hardness: 5-6 kg/cm²). Bulk and tapped densities were nearly identical for all formulations. Compressibility index and Hausner ratio ranged from ?18 to 1.09-1.21, indicating good flow properties. Tablet thickness ranged from 5.82 to 5.91 mm, hardness from 5.9 to 6.3 kg/cm², and friability was less than 1.0 %W/W. Drug content was between 98-102%. The controlled-release order from dissolution data was F9 > F7 > F8, showing optimal release with a combination of HPMC and two natural polymers.
In-Vitro antidiabetic activity of leaf juice of Mespilus Germanica L
Authors: Guduru Rajeswari , Ingilala Kalyani Prakashini
Published: July 2024

Diabetes mellitus, a modern civilization disease, is marked by chronic hyperglycemia and severe complications if untreated. Type II DM, a multifactorial form, accounts for 90% of global cases. Controlling postprandial glucose is vital for preventing complications, as elevated plasma glucose is influenced by ?-amylase and ?-glucosidases. Current enzyme inhibitors like Acarbose and voglibose cause gastrointestinal side effects. This study aimed to find natural source inhibitors with fewer adverse effects using in-vitro antidiabetic assays. Mespilus germanica L. leaf juice (20-100 ?g/ml) was tested against fungal ?-amylase and ?-glucosidases from albino rat intestines. The enzymes showed dose-dependent inhibition comparable to Acarbose. LJMG and Acarbose had IC50 values of 83.35 and 52.15 ?g/ml for fungal ?-amylase, and 92.44 and 54.84 ?g/ml for ?-glucosidase, respectively. The leaf juice had a protein content of 10.6 mg/ml and increased glucose uptake by yeast similarly to Metronidazole. Results suggest that polyphenolic compounds in the leaf juice mimic insulin in glucose utilization and inhibit ?-amylase and ?-glucosidase. Further pre-clinical assessments are needed to confirm the antidiabetic potential of this herb.
Imigrantes e seus direitos: um estudo bioético em diálogo com a perspectiva decolonial
Authors: Geraldo de Ávila Fábio , Quina  Pereira Camila Claudiano
Published: July 2024

No município de Espírito Santo do Dourado – Minas Gerais, Brasil, a intensificação do cultivo de lavouras de morango tem gerado um contínuo fenômeno de imigração de trabalhadores rurais proveniente das regiões Norte e Nordeste do país. Nesta pesquisa qualitativa e exploratória se propôs estudar este fenômeno, no que concerne à problematização bioética acerca de violações de direitos fundamentais aos imigrantes em sua trajetória de imigração e fixação. Foram realizadas entrevistas e aplicados questionários com imigrantes e servidores públicos municipais que atuam diretamente com esta população em que se analisou os resultados pelo método descritivo. A pesquisa concentrou na centralidade dos temas abordados para se tratar da realidade local, circunscrita nos projetos globais. Indicou-se que os imigrantes recebem atenção nas principais políticas públicas no município, ao passo que este teria dificuldades para lidar com o grande fluxo e com o choque cultural. Um diálogo entre Bioética de Intervenção e contorno do pensamento decolonial guiou a análise dos resultados.
Experiência de trabalho em um Hospital Público entre 1986 e 1993 – Plantando as sementes da Reforma Sanitária Brasileira
Authors: Eliane Aparecida da Cruz , Volnei Garrafa , Assunção Figueiredo Holanda Marianna
Published: July 2024

A Reforma Sanitária Brasileira foi resultado de um processo de mobilização que envolveu todo o país em defesa da saúde pública, gratuita e universal. Este artigo recupera a trajetória de um núcleo de trabalhadoras e trabalhadores de saúde do Hospital Nardini, em Mauá, São Paulo (SP), de 1986 a 1993, organizados em uma Comissão Sindical de Base (CSB) do Sindsaúde/SP, que repercutiu os resultados da 8ª Conferência Nacional de Saúde e a aprovação do Sistema Único de Saúde (SUS) na Constituição de Federal de 1988. O texto foi construído metodologicamente por meio de pesquisa qualitativa visando a trajetória desses atores no desenvolvimento de estratégias de mobilização social mediante composição de frentes de luta em defesa da saúde pública, favorecendo a ampliação dos serviços e a criação de conselhos locais de saúde. Experiências desse tipo fazem parte da construção histórica do SUS como sementes da Reforma Sanitária Brasileira.
A comparative analysis for identifying the polarity of people based on emotional pulse in a smart city
Authors: R. Kiran Kumar , Indira D. N. V. S. L. , Sri Jyothi Goriparthi , Pranati L. B. , Keerthi G.
Published: July 2024

Over the past decade, the field of industrial informatics has extensively studied smart-city applications. This paper proposes a method for identifying the polarity of people based on the emotional pulse of a city by using publicly available, large-scale social media interactions that capture individuals' ideas and beliefs. The effectiveness of the framework was assessed and controversial ideas and unpleasant arguments in the public sphere were tracked. The level of hostility was measured through online discussions using a Deep Learning (DL)-based classifier. Natural Language Processing (NLP) and Markov models have been used to characterize the mood of the general populace. The results and applications of Artificial Intelligence (AI) to identify citizens' emotional pulses could enhance security, communication, and policymaking.
Mesotelioma Peritoneal Multikistiko Onberaren Berrikusketa eta Kasu Aurkezpena
Authors: Astiazaran Aleman Garazi
Published: July 2024

Mesotelioma Peritoneal Multikistiko Onbera (MPMO) oso patologia ezohikoa da, batez ere ugalkortasun-aroko emakumeetan agertzen dena eta pronostiko ona duena. Mesotelioma gaiztoa ez bezala, ez da asbestoarekin erlazionatzen, baina haren etiopatogenia ez dago argi oraindik. Zenbait tratamendu mota probatu izan badira ere, gaur egun ez dago aukerako tratamendurik.
Donostia Unibertsitate Ospitalean (DUOn) MPMO duen 31 urteko emakume bat artatu zen duela gutxi. Diagnostikoa lesioaren biopsien azterketa anatomopatologikoaren bidez egin zen eta pazientea zitorredukzio-kirurgia eta kimioterapia intraperitoneal hipertermiko (HIPEC) bidez tratatu zen. Hiru hilera egindako OTan birgaixotze bat ikusi zen eta tratatzeko egindako ebakuntzako aurkikuntzengatik, asmo terapeutikoa alde batera utzi eta jarraipena egitea erabaki zen. Gaur egun pazienteak ez du sintomarik.
Lan honen xedea patologia ezohiko honi buruz gaur arte argitaratutako informazioa biltzea da, praktika klinikoan diagnostiko eta tratamendurako erabakian laguntzeko. Horretan laguntzeko DUOn izandako kasuaren berezitasunak azaldu dira.
Gastrektomiaren eragin pronostikoa urdaileko minbizi metastasikoan: Parekatzearen bidezko ikerketa eta pronostikoaren iragarle den no-mogramaren sorrera
Authors: De la Quintana Santacoloma Irune , Sarriugarte Lasarte Aingeru
Published: July 2024

Sarrera. Urdaileko minbizi gastriko garatuaren pronostikoan gastrektomiak duen eragina balioztatzea du helburu lan honek. Izan ere, minbizi gastriko metastasikoak pronostiko txarra du, eta ez da modu bateratuan maneiatzen. Nahiz eta gero eta ebidentzia handiagoa dagoen gaixotasun honetan kimioterapiak biziraupena luzatzen duela, ez dago argi tumore primarioaren erauzketak pronostikoan onurarik ekar dezakeen. Bestalde, gainerako tratamendu aringarriek bizitza luzatzen duten heinean eraginkortasuna galtzen dutenez, gastrektomia bera, neurri aringarri egokia izan daitekeen zalantza dago, biziraupena luzatzeaz gain, bizi-kalitatea ere hobe bailiezaieke ondo aukeratutako pazienteei.
Metodologia. Gurutzetako Ospitaleko Euskadiko tumoreen erregistrotik 2005-2014 urteetan urdaileko minbizia estadio metastasikoan diagnostikatutako pazienteen datuak jaso dira (N = 348). Aldi berean, Gurutzetako Ospitalean, Kirurgia Orokorreko zerbitzuan betetako datu-base prospektiboa erabili da, bertan operatutako gaixo horien datuak lortzeko. 1:1 parekatzeko analisia erabili da gastrektomia jasan duten pazienteen eta gastrektomiarik ez dutenen arteko ezaugarri kliniko orekatuak bermatzeko. Biziraupena aztertzeko datuak Kaplan-Meier eta Cox arrisku proportzionalen eredua erabiliz aztertu dira. Aldagai anitzeko Cox analisia erabili da nomograman pronostiko-aldagai iragarleak hautatzeko.
Emaitzak. Gastrektomizatuetan biziraupen-mediana ez-gastrektomizatuekin konparatuta 8 hilabete gehiagokoa izan da. Biziraupen-portzentajeak 6 hilabete, 1 eta 2 urterako % 35,7, % 16,3, % 7,4 (ez-gastrektomizatuetan), eta % 76,9, % 47,7, % 21,5 (gastrektomizatuetan) izan dira hurrenez hurren. Aldagai anitzeko analisietan, gastrektomia biziraupen global hobearekin erlazionatu da (HR= 0,17, CI95%= 0,11-0,29, p<0,001).
Ondorioak. Ikerketa honetan, ondo hautatutako pazienteetan, gastrektomiak minbizi gastriko hedatuaren biziraupena hobetzen duela ikusi da. Hala ere, emaitzak serie handiagoetan bermatu eta ausazko ikerketa prospektiboetan frogatu beharko lirateke ondorio sendoagoak lortzeko.
Aterosklerosiaren fisiopatologia: disfuntzio endotelialetik plakaren hausturara
Authors: Jebari Benslaiman Shifa , Larrea Sebal Asier , B.Uribe Kepa , Benito Vicente Asier , Galicia García Unai , San José Urteaga Ane , Martín César
Published: July 2024

Aterosklerosia gaixotasun kardiobaskularren arrisku-faktore nagusia da eta endotelioaren aktibazioarekin hasten da. Jarraian zenbait prozesu gertatzen dira, hala nola lipido eta zuntzezko elementuen metaketa eta kaltzifikazioa, zeinek ateroma-plakaren eraketa eta hantura-bidezidorren aktibazioa eragingo duten. Prozesu horiek odol-hodiaren estutzearekin batera, konplikazio klinikoak eragin ditzakete. Berrikuspen honetan aterosklerosiaren garapenaren atal desberdinak laburtzen dira, endotelioaren disfuntziotik hasita, plakaren apurketaraino. Horrez gain, gaixotasunaren gaur egungo tratamenduak ere azaltzen dira.
Arnasgune bateko haurrak eta hitanoa: hastapena eta helduen begirada
Authors: Eizmendi Otaegi Aiora
Published: July 2024

Urteek aurrera egin ahala hitanoa gero eta gutxiago erabiltzen da eta aurrerantzean ere bide beretik jarraitzeko joera erakusten du. Kezka horretatik abiatuta, Gipuzkoa erdigunean kokaturiko herri txiki bat oinarri hartuz, lan honen helburua da ezagutzea zein diren haurretan hitanoaren hastapenaren ezaugarriak eta horretan zer eragin duten generoak eta haurren inguruko pertsona erreferenteek. Horretarako, eskola txiki bateko kideen laguntzarekin, behaketa, elkarrizketa nahiz galdetegien bidez informazioa jaso da. Bildutakoarekin, hitanoaren ezaugarri tradizionalak mantentzen direla ikusi da, tratamendu hori batez ere genero maskulinoarekin lotzen jarraitzen baita, haurren artean mutiletan hitanoa asko entzuten den bitartean nesketan ia ez baita entzuten.
Euskal hedabide nagusiak eta espainiar hedabide nagusiak Udaberri Arabiarrean: gatazken jarraipena egiteko bi modu
Authors: Unda Endemaño Annette , Iturregui Mardaras Leire
Published: July 2024

Udaberri Arabiarra gatazken jarraipenean mugarrietako bat izan da, momentu hartan berritzaileak ziren sare sozialek ikuspegi berri bat eskaini baitzioten informaziojarraipenari eta aldaketa nabaria ekarri zuen kazetarien lan egiteko eran. Horrek guztiak eta hedabideek 2008. urtean jasandako krisiak eragin zuzena izan zuten hedabideen aurrekontuetan eta, beraz, kazetarien lan-baldintzetan. Testuinguru hori abiapuntu izanda, lan honek euskal hedabide nagusiek eta espainiar hedabide nagusiek egindako Udaberri Arabiarraren jarraipen mota ikertzeaz gain, gertera horien jarraipena egin zuten kazetarien lan-baldintzak aztertzea du helburu. Analisia egiteko, hedabide bakoitzeko nazioarteko saileko arduradunak identifikatu eta elkarrizketatu dira. Emaitza nagusien artean, nazioarteko gaietan eta bereziki gatazkei buruzko gaietan breaking news-en mendekotasun nagusia, kazetari freelance edoautonomoen presentzia nabaria eta lan-baldintza eskasak nabarmentzen dira, agerian utzita egoera horrek informazioan bertan eta profesionalen segurtasun-baldintzetan izan ditzazkeen inplikazioak.
Advertising discourse as modelling and semiotic activity
Authors: O.V. Boiko
Published: July 2024

The article is aimed at analysing the basic concepts of semiotics and their application in multimodal advertising texts of consumer goods. The purpose of the article is to study advertising discourse as a modelling and semiotic activity in English-language advertising discourse, as well as to outline the main semiotic strategies and linguistic means in the formation of English-language advertising messages. The main objectives are to review the works of Ukrainian and foreign researchers on the issue, to identify and describe the key semiotic strategies and linguistic means of English-language advertising texts, and to determine the role of semiotic strategies in interaction with the audience and their reproduction of cultural concepts through advertising communication. The article provides a comprehensive overview of some of the key principles and concepts of semiotics and their advertising relevance, highlighting the construction of denotative messages about a product and desired connotative associations. The article also explains the role of adherence to known codes and the use of intertextual references in advertisements to create a connection with the audience. This article draws heavily on fundamental semiotic theories such as Peirce's triadic sign model, the distinction between denotation and connotation, the role of codes and cultural conventions, and the phenomenon of intertextuality. The article shows how advertisers use signs, symbols and related meanings to create culturally resonating persuasive campaigns. The relevance of the study is to understand how advertising shapes attitudes and stereotypes, as well as how modern technologies change the ways of interacting with the audience through linguistic and semiotic strategies.
The Evolution of Donald Trump’s Image in Rap Lyrics
Authors: Riazanov Іhor
Published: July 2024

The paper researches the peculiarities of the development of the reference to Donald Trump in rap lyrics. The paper focuses on the analysis of stylistic devices and metaphors used by the authors of rap lyrics when referring to the image of Donald Trump as a businessman and politician; as well as the analysis of the sociocultural context of these references, their significance within the genre and American culture in general, and their stylistic effect.
Ukrainian Translation of English Lexicalized Constructions: A Case of BBC News and BBC News Ukraine Headlines
Authors: O.P. Deikun
Published: July 2024

Drawing on the headlines from the BBC News and BBC News Ukraine websites, the paper seeks to identify the patterns of translating English lexicalized constructions consisting of fixed and non-fixed elements. The fixed component is considered to be a stable island of reliability that has a phonological form unchanged in different contexts, while the non-fixed component is dependent and selected according to the communicative situation. The paper is the first study finding that English lexicalized constructions in BBC News headlines are translated on the BBC News Ukraine website according to four semantic patterns: re-perspectivation, generalization or specification of the meaning of the Ukrainian components of the English lexicalized constructions, as well as grammaticalization. The implementation of the re-perspectivation pattern involves shifting the focus of attention from one feature of a referent in the original to a different one in the translation with the help of adjectives or nouns. Within the generalization translation pattern of English lexicalized constructions, the semantics of their components shifts from the basic categorization level, associated with the speakers’ perceptual experience, to the superordinate level involving generalization. According to the specification pattern, the semantics of the English lexicalized constructions’ components shifts in translation from the basic to the subordinate categorization level, focusing on the specific features of referents. The shifts in the categorization levels, characteristic of the generalization and specification translation patterns, results from the peculiarities of the British and Ukrainian worldviews brought about by the nations’ histories and lifestyles. The grammaticalization patterns render the English lexicalized constructions into Ukrainian by the prepositional structures denoting CONTAINER and by the relative structures specifying the features of referents.
Brain Respiration, Stres, dan Romantic Relationship pada Dewasa Muda
Authors: Indrianie Efnie , Dwijayanthy Meta
Published: July 2024

Penelitian ini bertujuan untuk melihat bagaimana pengaruh Brain Respiration  dalam mengurangi stres yang berkaitan dengan romantic relationship pada dewasa muda. Quasi-experimental digunakan dalam penelitian ini, dan partisipan direkrut dengan menggunakan purposive sampling. Tiga puluh orang dewasa muda yang mengalami masalah romantic relationship terlibat dalam penelitian ini. Para peserta dibagi menjadi kelompok eksperimen dan kelompok kontrol dengan menggunakan randomized control. Untuk mengukur aktivitas elektrodermal (EDA) yang mencerminkan stres, penelitian ini menggunakan perangkat biofeedback. Analisis statistik yang digunakan adalah T-Test dan Mann-Whitney. Dari penelitian ini, ditemukan bahwa tingkat stres pada dewasa muda yang mendapatkan Brain Respiration mengalami penurunan (T-hitung = 0,001 < 0,05). Jika dibandingkan dengan kelompok kontrol, penurunan derajat stres pada dewasa muda pada kelompok eksperimen jauh lebih rendah (x̄ post-test kelompok eksperimen = 2,8 < x̄ post-test kelompok kontrol 4,8). Dalam hal ini dapat disimpulkan Brain Respiration dapat menurunkan derajat stres pada dewasa muda yang mengalami masalah percintaan.
Conference Report on the “Use of Epidemiological findings in Regulatory Pesticide Risk Assessment”
Authors:   European Food Safety Authority
Published: July 2024

In 2013, as a follow up of a systematic review of epidemiological studies published from 2006 to 2012 investigating the association between pesticide exposure and many health outcome, the European Food Safety Authority (EFSA) lauched a project with a mandate for Plant Protection Products and their Residues (PPR) Panel to examine novel tools to improve the use of epidemiological data in the risk assessment of pesticides. The project culminated in the publication of two scientific opinions and this report summarises the discussions and outcomes of the scientific conference, held on 21 November, 2017, in Parma, Italy. More than 65 people attended the Conference and speakers and participants from European and non‐European countries discussed the two opinions developed by the PPR Panel and future scenarios where the application of modern methodologies in toxicology, exposure and epidemiology are expected to support a mechanistic shift for the integration of the three disciplines in the pesticide risk assessment and identify risk factors involved in complex diseases.
A study of image autocorrelation as a method to characterize porosity and estimate permeability
Authors: Cobaleda Gloria
Published: July 2024

Ioannidis, et al., published a statistical methodology for analyzing of porous microstructure to estimate permeability in the Journal of Petroleum Science & Engineering. The method is based on the calculation of the autocorrelation function from binary images of porous space. This paper presents a systematic application of the methodology applied to twenty-three sandstone samples from a Colombian oil bearing formation. Images of porosity were acquired under different detection conditions in order to carry out a comparative evaluation of the results at different resolutions. It was found that the adjustment parameters for the autocorrelation function, as well as its derivative and integral, dependent strongly upon the conditions of image detection. Under conditions of maximum resolution, permeability was estimated within the same order of magnitude of the value measured experimentally, with an accuracy that varies from 1.6% to 24%.
Models to predict creep behavior of HK-40 steel
Authors: Latorre Guillermo
Published: July 2024

An analysis was conducted on the creep behavior of HK.40 steel. This steel is high heat resistant, aged during service, under the conditions of a petrochemical furnace. The different models that describe its creep behavior are discussed. The tests were carried out under a constant load intending to simulate the operating conditions of a catalytic reforming furnace. Among the models proposed in the literature, the models of Degui, Jaske-Simonen, Larson-Miller, Manson-Haferd and Snedden were applied. Another model is proposed to account for the three stages of creep. The samples of the material have had from 74 to 88 thousand hours of service and are tested at a constant load until rupturing.
Immiscibility phenomenon in low density branched polyethylene, PEED, films in blown film extrusion process
Authors: Morales P.C. , Salazar R.A.
Published: July 2024

The immiscibility in branched low-density polyethylene film was researched using techniques of instrumental analysis (FTIR, DRX, DSC, TGA, SEC-GPC, SEM-EDX) and rheometry (DMA, Capillary Rheomether). It was determined that immiscibility occurs when there are microentities generated by an undesirable polymer found in a low proportion in the mixture, characterized by different morphological and rheological properties regarding the LDPE prime, which makes up the plastic film. It was found that the LDPE polymer which forms the "fish-eyes" microentities has a wider distribution of molecular weights, low cristallinity, greater branching and a rheological behavior unlike the LDPE prime, causing this phenomenon in the extrusion process of the blown film. This is considered a significant defect in the quality of plastic film used for general-purpose packing.
Uses and Implications of Marijuana from the Perspective of Islamic Law
Authors: Abdulrahman Manswab Mahsen
Published: July 2024

Objectives: The study aims to determine whether all uses of Marijuana are considered haram (prohibited) or if there are any exceptions.
Methodology: It employed a qualitative methodology and rigorously examined relevant materials from a jurisprudential perspective, including textual and contextual aspects. Data for this study were sourced from various materials, including books, journal articles, reports, conference papers, and websites.
Findings: The research highlights the differences between hemp and Cannabis sativa, both types of marijuana plants, distinguished by their varying levels of tetrahydrocannabinol (THC). Hemp contains less than 0.3% THC, while Marijuana can have THC levels up to 28%. Marijuana is primarily used for recreational purposes, whereas hemp has numerous industrial applications such as textiles, rope, paint, clothing, shoes, paper, bioplastics, insulation, lotions, and more. Ultimately, the ruling on marijuana use varies between forbidden (haram) and permissible (halal), depending on the intent behind its use. This is consistent with the Islamic legal principle that the determining factors influence the law.
Originality: The study's findings will assist policymakers in effectively managing hemp, creating job opportunities, and significantly increasing tax revenue while implementing measures to prevent and control its use. The scientific value of this research lies in analyzing marijuana consumption from the perspective of the Sharia, which aligns with the higher objectives of Islamic law: preserving the mind and wealth.
RRI Lhokseumawe's Media Convergence in Maintaining Existence in the Digitalization Era
Authors: Marhamah  , Fauzi
Published: July 2024

Media convergence  presents both a challenge and a necessity for radio media in the digital era, due to the complexity of integrating information and communication technology, computer networks, and media content. RRI must adapt to changes in data usage patterns within society through media convergence to remain competitive and sustain its existence. This study aims to identify the aspects of media convergence at RRI Lhokseumawe that help maintain its presence in the digital era. The research is grounded in media convergence theory by Grant and Wilkinson and employs a qualitative research methodology. Data was collected through interviews, observations, and documentation. The research informants included eight individuals: the director of RRI, and members from the news, broadcasting, new media engineering departments, as well as RRI observers. Descriptive qualitative analysis was used to interpret the data. The stages of data analysis included data reduction, data display, and conclusion drawing/verification. The study found that RRI Lhokseumawe maintained its presence in the digital age by embracing convergence. This convergence was implemented through several channels, such as the website, RRI Go Play, YouTube channel, and RRI Net. As a result of this convergence, access became easier, allowing the public to access and enjoy information through smartphones anytime and anywhere. Additionally, the human resources at RRI Lhokseumawe underwent training to update their skills and abilities to keep pace with current technology.
OS DESAFIOS DE ACESSO E PERMANÊCIA DOS ESTUDANTES DE CAXINGÓ-PI PARA CURSAR O ENSINO SUPERIOR NA UNIRVESIDADE DO DELTA DO PARNAIBA-UFDPAR
Authors: Miranda Roziane Araujo
Published: July 2024

RESUMO
A intenção deste artigo é compreender o acesso e a permanência dos estudantes
que frequentam universidades fora de suas cidades de origem, bem como entender os
mecanismos utilizados pelo poder Público para promover educação e cidadania, tendo
como recorte espacial a Universidade Federal do Delta do Parnaíba (UFDPar), Campus
Sede. A escolha por Parnaíba– PI é baseada em seu contexto espacial relevante,
principalmente diante da promoção do ensino superior no estado do Piauí, tendo em vista
que esta é uma cidade média, reconhecida por concentrar importantes
Universidades/faculdades públicas e privadas.
O objetivo deste artigo foi investigar os desafios de acesso e permanência
dos estudantes de Caxingó-PI para cursar o ensino superior na Universidade Federal do
Delta do Parnaíba-UFDpar. a) Identificar os principais desafios enfrentados pelos
estudantes de Caxingó-PI para frequentar um curso de graduação na UFDpar. b) Analisar
os programas desenvolvidos pelos órgãos públicos que visem a permanência desses
estudantes ao longo de sua graduação c) Compreender as motivações que influenciam os
estudantes a ingressarem em um curso de graduação na UFDpar.
O percurso metodológico se deu por meio de pesquisas bibliográficas em artigos
publicados em anais, sites e plataformas como Google acadêmico, foi-se utilizado
diversas obras, destacando as principais Carvalho(2015) e Vasconcelos (2010). Essa
pesquisa pode contribuir para a compreensão dos desafios existentes no processo de
formação de estudantes que se encontram em meios desfavorecidos, analisando por meio
disso, a importância da elaboração de programas direcionados à entrada e permanência
nas IES.
Palavras-chave: Acesso. Permanência. Educação superior. Assistência.
HEGEL E A FILOSOFIA COLONIAL DA HISTÓRIA
Authors: Gonçalves Sergio dos Santos
Published: July 2024

Este artigo tem como objetivo realizar uma interpretação da Filosofia da História de Hegel, pois entende-se que essa obra está inserida em uma hermenêutica colonial, na medida de em que são seus ideais eurocêntricos e racistas que a fundamentam. Na primeira parte deste artigo é feito um recorte analítico da introdução da Filosofia da História de Hegel e seus principais pontos. Em seguida, na segunda parte, é demonstrado como essa obra do filósofo alemão está circunscrita em uma hermenêutica colonial. Por fim, é adotada uma interpretação da Filosofia da História hegeliana que afirma que se trata, de fato, de uma Filosofia Colonial da História, a entendendo como um sintoma da colonialidade, ao mesmo tempo que uma ferramenta de sua manutenção. É possível chegar a essa conclusão, pois se detecta que os padrões de sub-ontologização racial que a colonialidade e a modernidade trazem estão imbricados com a filosofia hegeliana de tal maneira que não é possível separar o pensamento do filósofo dessas crenças eurocêntricas e racistas.
¿Qué quiere el Feminismo Descolonial? Entrevista con Yuderkys Espinosa Miñoso
Authors: Martins Fernanda , Miñoso Yuderkys Espinosa , Li Leticia Povala
Published: July 2024

Espinosa Miñoso nos sitúa ante las heridas coloniales que permanecen abiertas y ardiendo en Abya Yala . Para que podamos comprender la lucha contra la violencia, contra la vulnerabilización de las vidas, es necesario permear matices más profundos para conectar las diferentes formas de romper con la destrucción y desear una “vida sabrosa”.
Descolonizar Afetos - caos, concomitância e movimento
Authors: Martins Fernanda
Published: July 2024

A presente entrevista realizada por Fernanda Martins à Geni Nuñez tem por objetivo pensar como o marco colonial produz afetos e organiza os modos de vida contemporâneos. A partir da cosmogonia Guarani, Geni Nuñez aposta na descolonização como um arcabouço de práticas possíveis que coloquem em evidência e fissurem as hierarquias impostas na organização social atual.