bluuebunny/crossref_metadata_2025 huggingface dataset:
Review of studies on the computational diagnosis of local defects of structural elements
Authors: Khakimov A.G.
Published: July 2019

Rods, beams, shafts, pipelines, round plates. membranes are parts of structures in which local defects such as cracks, dents, cavities, local corrosion can be formed. Provides an overview of the research A. G. Khakimov for the diagnosis of local defects. It is received: 1. The two eigenfrequencies of the longitudinal oscillations can determine the location and the notch parameter characterizing its size. 2. The three lower eigenfrequencies of the longitudinal oscillations can determine the initial coordinate and the value of the attached distributed mass to the stepped rod, as well as the ratio of the areas. 3. The solution of the inverse problem for extended rods allows us to determine the coordinate of the incision and the parameter containing its depth and length, according to the incident and reflected waves at the observation site. 4. The reflection from the air cavity and the passage of a longitudinal damped traveling wave in a pipeline immersed in a viscous liquid are determined, and the solution of the inverse problem allows to determine the coordinate of the air cavity and its length according to the reflected wave at the observation site. 5. The initial coordinate and the length of the longitudinal through radial section of the hollow shaft are determined by the two eigenfrequencies of torsional vibrations. 6. The coordinate, length and parameter of the drill string notch are determined by the three eigenfrequencies of the torsional vibrations. 7. The reflection from the distributed mass attached to the pipeline and the passage of the flexural traveling wave are considered. The dependence of the solution on the initial coordinate of the distributed mass and its magnitude is obtained, and the inverse problem of determining the initial coordinate of the distributed mass and its magnitude from the data of the reflected wave at the observation point is solved. 8. The radius and thickness of the thin central region of the membrane are determined by the two eigenfrequencies of the transverse vibrations. 9. The radius, thickness of the thinned central area of the plate and the value of the attached distributed mass are determined by the three natural frequencies of the bending oscillations. 10. By three frequencies of bending vibrations it is possible to determine the velocity parameter, the relative mass of the product per unit length of the pipeline and the relative mass of sediments on the walls of the pipeline and, as a consequence, the mass flow of liquid through the pipeline.
To the issue of the mechanism of cell migration
Authors: Rakhimov A.A. , Akhmetov A.T. , Valiev A.A. , Danilko K.V. , Sametov S.P. , Khismatullin D.B.
Published: July 2019

The paper presents the experimental and theoretical aspects of studying the migration of cancer cells through narrow microchannels when interacting with a chemical substance — an attractant. Chemical agents were injected directly from the respective separate reservoir via hydrostatic head. The presence of migration channels of different sizes allowed us to analyze the migration abilities inherent in the cells. Experimental studies on the migration of cancer cell lines were carried out using a microfluidic binary migration cell. It consists of two chambers 50 μm deep, connected by a series of narrow microchannels 10 μm high. The chambers are connected to the tanks from which cancer cells and activating media come. The model features smooth transitions from all tanks to microchannels to prevent accumulation of microbubbles and cells, the presence of a restrictive barrier between a chemoattractant container and a nutrient medium to reduce the effect of capillary forces, sealing the supply channels and cells with cells using a glass plate glued on top. In a series of experiments, the ability of epithelial-like cells of the metastatic prostate cancer DU145 to migrate in the migration microfluidic system developed by us was revealed. The nature of migration depends on the width of the channel and the location of the cells at the time of adding the chemical agent. In wider channels, cells adhere more slowly and are able to perform rolling movements. In narrower channels, the cells are spread over the glass. The mathematical model of concentration-capillary movement, which is a system of equations of the dynamics of an incompressible viscous fluid, written separately for the cell contents and for its environment, is considered as the basis for a theoretical study of cell migration.
The influence of the vortex tube channel length on the separation of air by its temperature
Authors: Adiullin B.R. , Mikhaylenko C.I.
Published: July 2019

Based on the prepared counterflow vortex tube model with four inlets, the effect of the length of the vortex tube channel on the generation of cold and hot air is investigated. In the simulation were used standard equations of gas dynamics, which include the equations of continuity, conservation of momentum, total energy, and the state of an ideal gas. To consider turbulent effects was chosen a -\varepsilon$ turbulence model. Computational experiments were carried out in the OpenFOAM software using the sonicFoam solver. The prepared grid allowed modeling vortex tubes with the main channel length varying from 20 to 70 cm. All calculations were carried out under the same boundary conditions with constant pressure at the inlets and atmospheric pressure at the hot and cold outlets. The constructed model adequately reproduces the two-vortex structure of the air flow in the vortex tube. To obtain and process the results were used OpenFOAM utilities and a script implementing the algorithm for averaging the values at the tube outlets written in Python. The results were obtained on the temperatures and mass flow rates of air in cold and hot outlets of the vortex tube depending on the length of the device. According to the analysis of the obtained data, it was shown that increasing the length of the channel of the vortex tube significantly increases the production of cold air with a certain increase in its temperature. An increase in the temperature of the produced hot air with an increase in the length of the vortex tube was also noted.
Influence of viscosity temperature dependence on the spectral characteristics of the thermoviscous liquids flow stability equation
Authors: Nizamova A.D. , Kireev V.N. , Urmancheev S.F.
Published: July 2019

The flow of a viscous model fluid in a flat channel with a non-uniform temperature field is considered. The problem of the stability of a thermoviscous fluid is solved on the basis of the derived generalized Orr-Sommerfeld equation by the spectral decomposition method in Chebyshev polynomials. The effect of taking into account the linear and exponential dependences of the fluid viscosity on temperature on the spectral characteristics of the hydrodynamic stability equation for an incompressible fluid in a flat channel with given different wall temperatures is investigated. Analytically obtained profiles of the flow rate of a thermovisible fluid. The spectral pictures of the eigenvalues of the generalized Orr-Sommerfeld equation are constructed. It is shown that the structure of the spectra largely depends on the properties of the liquid, which are determined by the viscosity functional dependence index. It has been established that for small values of the thermoviscosity parameter the spectrum compares the spectrum for isothermal fluid flow, however, as it increases, the number of eigenvalues and their density increase, that is, there are more points at which the problem has a nontrivial solution. The stability of the flow of a thermoviscous fluid depends on the presence of an eigenvalue with a positive imaginary part among the entire set of eigenvalues found with fixed Reynolds number and wavenumber parameters. It is shown that with a fixed Reynolds number and a wave number with an increase in the thermoviscosity parameter, the flow becomes unstable. The spectral characteristics determine the structure of the eigenfunctions and the critical parameters of the flow of a thermally viscous fluid. The eigenfunctions constructed in the subsequent works show the behavior of transverse-velocity perturbations, their possible growth or decay over time.
Antimicrobial Peptides-based Nanostructured Delivery Systems: An Approach for Leishmaniasis Treatment
Authors: Rodríguez-Carlos Adrian , Martinez-Gutierrez Fidel , Torres-Juarez Flor , Rivas-Santiago Bruno
Published: July 2019

Background:

Leishmaniasis is a major health problem mainly in tropical and subtropical areas worldwide, although in the last decades it has been treated with the use of conventional drugs such as amphotericin, the emergence of multidrug-resistant strains has raised a warning signal to the public health systems thus a new call for the creation of new leishmanicidal drugs is needed.

Methods:

The goal of this review was to explore the potential use of antimicrobial peptides-based nanostructured delivery systems as an approach for leishmaniasis treatment.

Results:

Within these new potential drugs, human host defense peptides (HDP) can be included given their remarkable antimicrobial activity and their outstanding immunomodulatory functions for the therapy of leishmaniasis.

:

Though several approaches have been done using these peptides, new ways for delivering HDPs need to be analyzed, such is the case for nanotechnology.
Reviewing the Mechanistic Evidence Assessors E-Synthesis and EBM+: A Case Study of Amoxicillin and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Authors: Abdin Ahmad Y. , Auker-Howlett Daniel , Landes Jürgen , Mulla Glorjen , Jacob Claus , Osimani Barbara
Published: July 2019

Background:

Basic science has delivered unprecedented insights into intricate relationships on the
smallest scales within well-controlled environments. Addressing pressing societal decision problems requires an
understanding of systems on larger scales in real-world situations.

Objective:

To assess how well the evidence assessors E-Synthesis and EBM+ assess basic science findings to
support medical decision making.

Method:

We demonstrate the workings of E-Synthesis and EBM+ on a case study: the suspected causal connection
between the widely-used drug amoxicillin (AMX) and the putative adverse drug reaction: Drug Reaction
with Eosinophilia and Systemic Symptoms (DRESS).

Results:

We determine an increase in the probability that AMX can cause DRESS within the E-Synthesis approach
and using the EBM+ standards assess the basic science findings as supporting the existence of a mechanism
linking AMX and DRESS.

Conclusions:

While progress is made towards developing methodologies which allow the incorporation of basic
science research in the decision making process for pressing societal questions, there is still considerable need for
further developments. A continued dialogue between basic science researchers and methodologists, philosophers
and statisticians seems to offer the best prospects for developing and evaluating continuously evolving methodologies.
Cardiotoxicity Assessment of Drugs Using Human iPS Cell-Derived Cardiomyocytes: Toward Proarrhythmic Risk and Cardio-Oncology
Authors: Satsuka Ayano , Kanda Yasunari
Published: July 2019

Growing evidence suggests that Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
(hiPSC-CMs) can be used as a new human cell-based platform to assess cardiac toxicity/safety
during drug development. Cardiotoxicity assessment is highly challenging due to species differences
and various toxicities, such as electrophysiological and contractile toxicities, which can result in
proarrhythmia and heart failure. To explore proarrhythmic risk, the Multi-Electrode Array (MEA) platform
is widely used to assess QT-interval prolongation and the proarrhythmic potential of drug candidates
using hiPSC-CMs. Several consortiums, including the Comprehensive in vitro Proarrhythmia
Assay (CiPA) and the Japanese iPS Cardiac Safety Assessment (JiCSA), have demonstrated the applicability
of hiPSC-CMs/MEA for assessing the torsadogenic potential of drug candidates. Additionally,
contractility is a key safety issue in drug development, and efforts have been undertaken to measure
contractility by a variety of imaging-based methods using iPS-CMs. Therefore, hiPSC-CMs might
represent a standard testing tool for evaluating the proarrhythmic and contractile potentials. This review
provides new insights into the practical application of hiPSC-CMs in early or late-stage nonclinical
testing during drug development.
Preparation and Characterization of the Biological Compound Effervescent Granule of Calcium Acetate
Authors: Liu Zhongbing , Sun Xuemei , Liang Tiantian , Luo Yi , Chen Xiaoyan , Li Ting , Chen Lin , Wang Junjie , Lin Yan , Ye Yun , Zhong Zhirong
Published: July 2019

Objective:

Calcium acetate (Ca(CH3COO)2) is commonly used in calcium supplement for
medicine, which is used as an auxiliary agent to treat osteoporosis. An effervescent granule is widely
used in medical industry due to its palatability. The purpose of this study is to develop a new preparation
of compound effervescent granule of the biological calcium acetate (Ca(CH3COO)2 effervescent
granule), overcoming the disadvantages of the previous other dosage forms of calcium and thus enhancing
the therapeutic efficacy.

Methods:

The biological Ca(CH3COO)2 effervescent granule was prepared by the wet granulation
method. The formulation was optimized by the orthogonal experiment. The effervescent base was
comprised of various amounts of citric acid and sodium bicarbonate. Other ingredients were added for
optimal performance of effervescent granule. The performed Ca(CH3COO)2 effervescent granule was
evaluated for the particle size, repose angle, pH value of solution, calcium acetate content and effervescence
time. The in vivo effects of Ca(CH3COO)2 effervescent granule on the bone microarchitecture
were investigated via Micro-CT detection, and the serum calcium level was also investigated.

Results:

The optimized formulation of the biological Ca(CH3COO)2 effervescent granules was composed
of calcium acetate, citric acid, sodium bicarbonate, PEG6000, aspartame, PVP ethanol solution,
lactose and vitamin D. Our findings reveal that this biological Ca(CH3COO)2 effervescent granule exhibited
prominent effect on preventing the bone-mass loss and did better in enhancing the bone microarchitecture
compared to the other calcium preparations.

Conclusion:

The biological Ca(CH3COO)2 effervescent granule is a novel dosage form among so
many kinds of calcium preparations. It may perform better functions in the dairy calcium supplement.
Reverse Micellar System in Protein Recovery - A Review of the Latest Developments
Authors: Sankaran Revathy , Bong Jenn Hau , Chow Yin Hui , Wong Fadzlie Wong Faizal , Ling Tau Chuan , Show Pau Loke
Published: July 2019

Reversed micellar system (RMS) is an innovative technique used for the isolation, extraction
and purification of proteins and enzymes. Studies have demonstrated that RMS is an efficient purification
technology for extracting proteins and enzymes from natural plant materials or fermentation broth. Lately,
reverse micelles have wider biological applications and the ease of scaling up and the possibility for the
continuous process have made RMS a vital purification technique in various fields. In this study, an extensive
review of RMS with the current application in biotechnology is examined. This review provides
insights into the fundamental principles, key variables and parameters of RMS. In addition, a comparative
study of RMS with other liquid-liquid extraction techniques is also included. The present review aims to
provide a general overview of RMS by summarising the research works, since the introduction of the
technology to current development.
An Improved Scatter Search Algorithm for Parameter Estimation in Large-Scale Kinetic Models of Biochemical Systems
Authors: Remli Muhammad Akmal , Mohamad Mohd Saberi , Deris Safaai , Sinnott Richard , Napis Suhaimi
Published: July 2019

Background:

Mathematical models play a central role in facilitating researchers to better
understand and comprehensively analyze various processes in biochemical systems. Their usage is
beneficial in metabolic engineering as they help predict and improve desired products. However, one
of the primary challenges in model building is parameter estimation. It is the process to find nearoptimal
values of kinetic parameters which may culminate in the best fit of model prediction to experimental
data.

Methods:

This paper proposes an improved scatter search algorithm to address the challenging parameter
estimation problem. The improved algorithm is based on hybridization of quasi opposition-based
learning in enhanced scatter search (QOBLESS) method. The algorithm is tested using a large-scale
metabolic model of Chinese Hamster Ovary (CHO) cells.

Results:

The experimental result shows that the proposed algorithm performs better than other algorithms
in terms of convergence speed and the minimum value of the objective function (loglikelihood).
The estimated parameters from the experiment produce a better model by means of obtaining
a reasonable good fit of model prediction to the experimental data.

Conclusion:

The kinetic parameters’ value obtained from our work was able to result in a reasonable
best fit of model prediction to the experimental data, which contributes to a better understanding and
produced more accurate model. Based on the results, the QOBLESS method can be used as an efficient
parameter estimation method in large-scale kinetic model building.
Structural and Functional Analysis of Mutated Human Pyrin B30.2 Domain
Authors: Parvizpour Sepideh , Jomah Ashraf Fadhil , Razmara Jafar
Published: July 2019

Background:

Familial Mediterranean Fever (FMF) is a prototypical hereditary
autoinflammatory disease affecting principally Mediterranean populations and characterized by
recurrent frequent fever and inflammation. The disease is essentially caused by inherited mutations in
the MEFV gene which encodes pyrin protein. The reported mutations are mostly located on the B30.2
domain in the C-terminal end of the protein.

Objective:

The present study reports a structural comparison of the five most common mutated
structures including M694V, V726A, M694I, R761H, and M680I. The aim of this study was to
determine the structural and functional disorders caused by the mutations in the human pyrin protein.

Results:

The comparison revealed that all mutations make overall changes in the structure of the
domain. Further, the effects of these mutations on structural and molecular behavior of the B30.2
domain were compared with the native structure using MD simulation by GROMACS software. The
results revealed that all the studied mutants have a destabilizing effect on the protein structure.
Additionally, analyzing the projection of the motions of the proteins in phase space demonstrates high
rigidity of the mutated structures in comparison with the native protein.

Conclusion:

The results of simulations elucidate how the mutations affect the physiological
functioning of the pyrin B30.2 domain and cause the occurrence of the FMF disease.
Design, Synthesis, Insecticidal Evaluation and Modeling Studies on 1,4,6,7- tetrahydropyrazolo[3,4-d][1,3]oxazine Derivatives: An Application of Scaffold Hopping Strategy on Fipronil
Authors: Li Guanglong , Zhou Cong , Zhu Chengchun , He Lujue , Li Xiaoyang , Xu Zhiping , Xu Xiaoyong , Shao Xusheng , Li Zhong , Cheng Jiagao
Published: July 2019

Background::

As the first phenylpyrazole pesticide, fipronil has been widely used in crop protection and public hygiene. In the low energy conformation of fipronil, a pseudo-six-membered ring is observed through an intramolecular hydrogen bond.

Methods: :

A scaffold hopping strategy was applied to mimic the pseudo-six-membered ring of fipronil by non-aromatic ring. All compounds were synthesized with a proper synthetic route and characterized by 1H NMR, 13C NMR and high-resolution mass spectra. Insecticidal activities of all target compounds against Plutella xylostella were assessed by a professional organization. Physicochemical property prediction and docking study of these compounds with GABA receptor were also performed.

Results::

A series of 1,4,6,7-tetrahydropyrazolo[3,4-d][1,3]oxazine derivatives containing twenty-five compounds were designed, synthesized and evaluated. Several compounds exhibited moderate activities against Plutella xylostella. The strong electron-withdrawing groups are conducive to improve activities of this series of compounds against Plutella xylostella. Docking study showed that the most active compound 10 with nitro group could bind within the TM2 domain of GABA receptor, in which a hydrogen bond was observed with residue 6’Thr. The activity of 10 was weaker than fipronil due to the differences in physicochemical properties.

Conclusion: :

More attention should be paid to physicochemical properties during novel pesticide hit or lead design through scaffold hopping.
Natural Products from Mediterranean Diet: From Anti-hyperlipidemic Agents to Dietary Epigenetic Modulators
Authors: Georgia-Eirini Deligiannidou , Athina Sygkouna , Wim Vanden Berghe , Christos Kontogiorgis , Theodoros Constantinides
Published: July 2019

Background:

Cardiovascular Diseases (CVD) are, currently, the major contributor to global mortality and will continue to dominate mortality rates in the future. Hyperlipidemia refers to the elevated levels of lipids and cholesterol in the blood, and is also identified as dyslipidemia, manifesting in the form of different disorders of lipoprotein metabolism. These abnormalities may lead to the development of atherosclerosis, which can lead to coronary artery disease and stroke. In recent years, there is a growing interest in the quest for alternative therapeutic treatments based on natural products, offering better recovery and the avoidance of side effects. Recent technological advances have further improved our understanding of the role of epigenetic mechanisms in hyperlipidemic disorders and dietary prevention strategies.

Objective:

This is a comprehensive overview of the anti-hyperlipidemic effects of plant extracts, vegetables, fruits and isolated compounds thereof, with a focus on natural products from the Mediterranean region as well as the possible epigenetic changes in gene expression or cardiometabolic signaling pathways.

Methods:

For the purpose of this study, we searched the PubMed, Scopus and Google Scholar databases for eligible articles and publications over the last five years. The keywords included: “hyperlipidemia”, “plant extract”, “herbs”, “natural products”, “vegetables”, “cholesterol” and others. We initially included all relevant articles referring to in vitro studies, animal studies, Randomized Controlled Trials (RCTs) and previous reviews.

Conclusion:

Many natural products found in the Mediterranean diet have been studied for the treatment of hyperlipidemia. The antihyperlipidemic effect seems to be dose and/or consumption frequency related, which highlights the fact that a healthy diet can only be effective in reversing disease markers if it is consistent and within the framework of a healthy lifestyle. Finally, epigenetic biomarkers are increasingly recognized as new lifestyle management tools to monitor a healthy dietary lifestyle for the prevention of hyperlipidaemic disorders and comorbidities to promote a healthy life.
Meniscal Lesions in Geriatric Population: Prevalence and Association with Knee Osteoarthritis
Authors: Özdemir Meltem , Kavak Rasime
Published: July 2019

Objective:

This study evaluated the prevalence of different types of meniscal lesions
among elderly patients with knee pain. Moreover, this study assessed the relationship between meniscal
lesions and the presence of radiographic knee osteoarthritis (OA) in the elderly population.

Methods:

The radiographs and magnetic resonance images of one knee out of 306 patients with
knee pain aged 65-89 years were reviewed for knee OA and meniscal lesions. The prevalence of
different types of meniscal lesions was calculated, and the relationship between the prevalence of
meniscal lesion types and the presence of radiographic knee OA was analyzed.

Results:

Among 306 participants, 274 (89.5%) showed radiographic knee OA. We found one or
more meniscal lesion(s) in 93% of the total subjects, in 94% of all patients with knee OA, and in
84% of all patients without knee OA. The prevalence of surgically target, possible-target, and nontarget
lesions were 24%, 72%, and 69%, respectively. The prevalence of surgically target lesions
was significantly higher in patients with knee OA than in those without it. The most common lesion
observed was meniscal extrusion, followed by the horizontal and complex meniscal tears.

Conclusions:

Our results demonstrated that meniscal damage is considerably prevalent among elderly
individuals with knee pain, especially in those with knee OA. The fact that surgically target
and possible-target lesions constitute a substantial proportion of these lesions should be considered
in the clinical approach to these patients.
Research Progress and New Patents of Magnetic Grinding Machine
Authors: Li Yuan , Dai Ye , Qi Yunshan , Gao Yufei
Published: July 2019

Background:

Mechanical parts in processing and manufacturing process will produce burr,
scratches and other surface quality problems, which have adverse effects on the precision, use, reprocessing
location, operation safety and appearance quality of the parts, so it is necessary to grind the
workpiece surface.

Objective:

Based on the recent development in the field of magnetic grinding and related patent research,
it can provide reliable help to solve the problem of finishing the surface of parts with complex
shapes and small volumes.

Methods:

This paper reviewed some patents and research advances related to magnetic abrasive finishing,
and the advantages and disadvantages of the magnetic grinding machine in the finishing process
were summarized. The outstanding grinding effect of the new vibration assisted magnetic grinder was
introduced.

Results:

The working characteristics of various magnetic grinding machines were summarized, and the
development trend of magnetic grinding and finishing was prospected.

Conclusion:

Magnetic abrasive finishing has good flexibility, strong self-sharpening, wide applicable
scope, high processing efficiency, simple processing equipment and low cost. It can control the grinding
efficiency and grinding precision. The machining efficiency and quality of magnetic grinding can
be improved with the appropriate amplitude of vibration assist, and the surface quality can be improved
significantly.
Pengembangan video pembelajaran sinyal-sinyal wasit bola basket untuk guru penjasorkes sekolah menengah atas
Authors: Pambudi Duwi Kurnianto , Suharjana Suharjana
Published: July 2019

Penelitian ini bertujuan untuk mengembangkan video pembelajaran sinyal-sinyal wasit sesuai dengan Fiba rules 2014 untuk Guru Penjasorkes SMA. Metode penelitian ini meliputi : (1)potensi dan masalah, (2) pengumpulan data, (3) desain produk, (4) validasi desain, (5) revisi desain, (6) ujicoba produk, (7) revisi produk, (8) ujicoba pemakaian, (9) revisi produk,(10) produksi masal. Subjek penelitian ini berjumlah 33 guru. Pengumpulan data menggunakan angket lembar penilaian produk dengan disertai lembar saran dan masukan untuk revisi produk. Analisis data menggunakan teknik analisis deskriptif dengan menggunakan persentase. Hasil penelitian adalah sebagai berikut: hasil validasi ahli media dan ahli materi menunjukkan nilai 88,58% dan berkategori sangat tinggi. Hasil ujicoba produk menunjukkan nilai 93,33% berkategori sangat tinggi. Hasil ujicoba pemakaian menunjukkan nilai 92,59%, berkategori sangat tinggi. Hasil uji efektifitas/ uji operasional data  pretest dan post test pada uji efektifitas/ uji operasional menunjukkan peningkatan rata-rata nilai sebesar 9,09% yaitu dari 74,24% pada saat pretest menjadi 818,33% pada saat post test. Developing Learning Video of Basketball Referee Signals for Physical Education Teachers in Senior High School AbstractThis research aims to develop learning video of basketball referee signals based on Fiba Rules 2014 to physical education teacher of the senior high school. This research method includes: (1) the potentials and problems, (2) data collection, (3) the design of the product, (4) design validation, (5) design revisions, (6) test products, (7) product revision, (8 ) user trial, (9) the revision of the product, (10) the mass production. Subjects of this study are 33 teachers. Collecting data using a questionnaire sheet product assessment, accompanied by pieces of advice and input for the revision of the product. Data analysis using descriptive analysis techniques using percentages. The results of the study are as follows: the results of validation media experts and subject matter experts demonstrate the value of 88.58% and a very high category. The trial results demonstrate the value of 93.33% product category is very high. User trial results demonstrate the value of 92.59%, a very high category. The results of effectiveness test / operational test data are pre-test and post-test on the effectiveness test / operational test showed an average increase in value by 9.09% from 74.24% at the time of the pre-test be 818.33% at the post-test.
Motivasi berolahraga atlet atletik dan tinju
Authors: Blegur Jusuf , Mae Ramona Mathias
Published: July 2019

Tujuan penelitian ini adalah untuk melakukan uji perbandingan motivasi berolahraga antara atlet atletik dan atlet tinju di Pusat Pendidikan dan Latihan Pelajar Provinsi Nusa Tengara Timur dengan melibatkan 26 orang sampel (13 atlet atletik dan 13 atlet tinju). Penelitian ini menggunakan pendekatan kuantitatif dengan desain komparatif. Data penelitian dikumpulkan menggunakan The Sport Motivational Scale (SMS) yang dikembangkan oleh Luc G. Pelletier, Michelle Fortier, Robert J. Vallerand, Nathalle M. Briere, Kim M. Tuson, dan Marc R. Blais pada tahun 1995. Hasil penelitian menunjukkan bahwa motivasi berolahraga atlet atletik dan tinju tergolong baik, masing-masing 69.2% dan 92.3%. Nilai rata-rata atlet tinju lebih tinggi daripada atlet atletik, namun nilai standar deviasi atlet atletik lebih tinggi daripada atlet tinju. Secara umum, tidak ada perbedaan yang signifikan antara rata-rata variabel motivasi berolahraga atlet atletik dan atlet tinju (0.703 > 0.05). Akan tetapi, pada sub variabel motivasi intrinsik-to experience stimulation, terdapat perbedaan yang signifikan (0.004 < 0.05) dari kedua kelompok sampel penelitian. Sport motivation of athletic and boxing athleetes AbstractThe objective of this research is to do a comparison test between athletic and boxing athletes’ sport motivation in Student Education and Training Center, East Nusa Tenggara  by involving 26 athletes as the sample  (13 athletic athletes and 13 boxing athletes).This research used quantitative approach with comparative design.  Data was collected using The Sport Motivation Scale (SMS) created by Luc G. Pelletier, Michelle Fortier, Robert J. Vallerand, Nathalle M. Brierre, Kim M. Tuson, and Marc R. Blas in 1995. The result indicates that the level of athletic and boxing athlete’s’ sport motivation was good, respectively 69.2% and 92.3%. The average value of the boxing athletes is higher than the athletic athletes while the standard deviation value of the athletic athletes is higher than the boxing athletes. Generally, there is no significant difference between sport motivation toward the two sample groups (0.703 > 0.05). However, there is a significant difference (0.004 < 0.05) in sub-variables of intrinsic motivation to experience stimulation from both research sample groups.
The influence of emotional intelegence, self-efficacy, and altruism on teacher’s competence in inclusion elementary school
Authors: Septiana Devalia
Published: July 2019

This study aimed to: (1) describe emotional intelligence, self-efficacy, altruism, and teachers’ performance who teach in inclusion elementary schools of Karanganyar District, and (2) determine the effect of emotional intelligence, self-efficacy, and altruism on teachers competence who teach in inclusion elementary school of Karanganyar District. The research was quantitative research using the ex-post facto method. The results of the study show that: (1) teacher’s emotional intelligence is at the medium category, while self-efficacy, altruism, and teachers competence who teach in inclusion elementary school of Karanganyar District are in high category; (2) there is a significant relationship between emotional intelligence with the teacher’s competence, with a value of r = 0.560 (r > 0,244 ),  there is a significant relationship between self-efficacy with teacher’s competence with a value of r =0.535 ( r > 0.244), there is a significant relationship between altruism with the teacher’s competence, with a value of r = 0.711 (r > 0.244 ) and there is a significant relationship between emotional intelligence, self-efficacy, and altruism with the teacher’s competence, with a value of F = 39.742 (F > 2.76). Therefore, it concluded that higher emotional intelligence, and altruism the higher the teacher’s competence.
Utilization of interactive multimedia to improve learning interest and learning achievement of child
Authors: Primamukti Agatha Devian , Farozin Muh
Published: July 2019

This research aimeds to find out (1) the effect of interactive multimedia on the learning interest, (2) the effect of interactive multimedia on the learning achievement, (3) the different effect of interactive multimedia and image media on the learning interest and learning achievement of grade IV students of elementary schools in Wonosari Gunungkidul. This research was a quasi experimental. The design which was used was pretest-postest control group design with two experimental groups taught by using interactive multimedia and one control group using the image media. The data analysis used the paired sample t-test and independent sample t-test. The result of the research showed that: (1) there was an effect of interactive multimedia on the learning interest at the significance level of 0.000 < 0.05, (2) there was an effect of interactive multimedia on the learning achievement at the significance level of 0.000 < 0.05, and (3) the big different effect of interactive multimedia and image media on the learning interest and learning achievement was the learning interest with the gained score 10.412 for the experimental class 1 and 13.004 the experimental class 2, and the learning achievement with the gained score 8.703 the experimental class 1 and 6.810 the experimental class 2.
Pengembangan model pembelajaran tematik integratif penjasorkes berbasis permainan siswa sekolah dasar
Authors: Widodo Agung
Published: July 2019

Penelitian ini bertujuan untuk menghasilkan model pembelajaran tematik integratif Penjasorkes berbasis permainan bagi siswa sekolah dasar kelas 1 Kecamatan Gantiwarno Klaten. Penelitian ini merupakan penelitian dan pengembangan yang terdiri atas dua tahapan yaitu tahap penelitian pendahuluan terdiri dari kajian literatur, kajian penelitian relevan, studi lapangan dan tahap pengembangan terdiri perencanaan, validasi ahli, uji skala kecil, dan uji skala besar. Validasi melibatkan 3 orang ahli. Uji skala kecil dilakukan terhadap 16 siswa kelas 1 dan 2 orang guru di sekolah dasar Muhammadiyah Gantiwarno. Uji skala besar dilakukan terhadap dua kelas yang masing-masing terdiri dari 26 siswa kelas 1 dan 3 orang guru di sekolah dasar Muhammadiyah Gantiwarno dan sekolah dasar Negeri Ngandong 2. Hasil penelitian berupa model pembelajaran tematik integratif Penjasorkes berbasis permainan bagi siswa sekolah dasar kelas 1 Kecamatan Gantiwarno Klaten. Model disusun dalam buku petunjuk dengan judul “model permainan integratif bagi siswa sekolah dasar kelas 1”. Berdasarkan penilaian para ahli, isi materi sangat baik, bahasa sangat baik, dan format penulisan sangat baik. Berdasarkan uji skala kecil dan besar secara substansi dan pelaksanaan tergolong sangat baik. Developing a thematic integrative learning model of physical education based on games for students of elementary school  AbstractThis research aims to develop a thematic integrative learning model of physical education based on games for students of grade 1 elementary school in Gantiwarno Klaten District. This study is a research and development which consists of two stages: preliminary research stage consisted of a literature review, a review of relevant research, field studies and stage of development consisted of planning, expert validation, small-scale testing and large-scale testing. The validation involved three experts. The trials were conducted in a small-scale with 16 students in grade 1 and two teachers in Elementary School Muhammadiyah Gantiwarno. The large-scale trials were conducted with two classes, each consisting of 26 students in grade 1 and three teachers in Elementary School Muhammadiyah Gantiwarno and State Elementary School 2 Ngandong. The results of the study are in the form of a thematic integrative learning model of physical education based on games for students of elementary school grade 1 in Gantiwarno Klaten Districts. The model is arranged in the guidebook with the title “an integrative model of the game for primary school students in grade 1”. Based on the assessment of the experts, this guidebook has a very good content material, very good language, and very good writing format. Based on the small-scale and large-scale test, the substance is classified as very good and its implementation is quite very good.
Pemberdayaan pedagang pasar tradisional dalam pondok komunitas belajar di sanggar kegiatan belajar Kabupaten Wonogiri
Authors: Ningrum Marta Dwi , Sujarwo Sujarwo
Published: July 2019

Penelitian ini bertujuan untuk mendiskripsikan pelaksanaan, hasil, dan faktor keberhasilan program pemberdayaan pedagang pasar tradisional dalam pondok komunitas belajar di SKB Kabupaten Wonogiri. Penelitian ini merupakan penelitian kualitatif dengan metode diskripsi. Teknik pengumpulan data yang digunakan yaitu wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa (1) Pemberdayaan dapat dilakukan melalui kegiatan pelatihan yang disesuaikan dengan kebutuhan sasaran program. Pemberdayaan pedagang pasar tradisional dalam pondok komunitas belajar di SKB Kabupaten Wonogiri dilaksanakan melalui kegiatan pelatihan tata boga dan tata rias. (2) Hasil program pondok komunitas belajar meliputi penambahan pengetahuan dan ketrampilan, adanya kesadaran untuk menambah pengetahuan dan ketrampilan, penambahan relasi, dan kegiatan usaha.(3) Faktor keberhasilan program meliputi perencanaan program yang matang, motivasi belajar warga belajar yang tinggi, ketepatan materi dan metode pembelajaran, narasumber yang berkompeten dan penggunaan strategi pembelajaran yang tepat, dan sarana prasarana yang memadai. Empowering Traditional Market Traders in the Learning Community Cottage in Community Learning Center (SKB) Wonogiri AbstractThis research aims to describe: the implementation, results, and success factors of the empowerment traditional market traders in the learning community cottage in SKB Wonogiri.This research is qualitative research with description method. Data collection techniques used were interviews, observation, and documentation. The results show that (1) Empowerment can be done through training activities tailored to the needs of program targets. The empowerment of traditional market traders in the community learning cottage in SKB Kabupaten Wonogiri is conducted through culinary and makeup training activities; (2) The results of the traditional market traders empowerment program in the community cottage of learn include expansion of knowledge and skills, their awareness to increase knowledge and skills, and increase relationships and enterpreneur activities.(3) Success factors include planning programs, sound program, the motivation to learning participants of high learning, precision materials and methods of learning, competent resource persons and the use of appropriate learning strategies, and adequate infrastructure.
Evaluasi program pelatihan keterampilan mengolah limbah kertas semen pada PKBM Cahaya Kota Binjai
Authors: Irwan Mahfuzi
Published: July 2019

Penelitian ini bertujuan mengevaluasi: (1) context, (2) input, (3) process dan (4) product program pelatihan keterampilan mengolah limbah kertas semen yang diselenggarakan Pusat Kegiatan Belajar Masyarakat (PKBM) Cahaya. Penelitian evaluasi ini menggunakan model CIPP yang dikembangkan oleh Stufflebeam (1986) dengan pendekatan deskriptif kuantitatif. Sampel penelitian dalam evaluasi ini yaitu 21 orang peserta pelatihan keterampilan, lima orang fasilitator pelatihan, dan satu orang penyelenggara program. Instrumen pengumpul data penelitian yang digunakan ialah kuisioner dengan menggunakan skala Likert, Acuan penilaian kriteria yang dipakai adalah penilaian acuan patokan (PAP). Hasil penelitian menunjukkan bahwa (1) aspek context program pelatihan keterampilan mengolah limbah kertas semen berada dalam kategori baik dengan  rerata skor sebesar 3,00 dari total skor yang telah ditetapkan; (2) aspek input program pelatihan keterampilan mengolah limbah kertas semen  berada dalam kategori baik dengan rerata skor sebesar 2,59 dari total skor yang telah ditetapkan; (3) aspek process program pelatihan keterampilan mengolah limbah kertas semen berada dalam kategori baik dengan rerata skor sebesar 2,53 dari total skor yang telah ditetapkan; dan (4) aspek product program pelatihan keterampilan mengolah limbah kertas semen berada dalam kategori tidak baik dengan rerata skor sebesar 2,06 dari total skor yang telah ditetapkan. An evaluation of the skills training program on processing cement waste paper at the community learning center Cahaya in Binjai AbstractThis study aims to evaluate: (1) the context, (2) input, (3) process, and (4) product of the life skills training program on processing cement waste paper organized CLC Cahaya. This evaluation study used the CIPP model developed by Stufflebeam (1986) with the quantitative descriptive approach. The research sample included 21 participants of life skills training, five training facilitators, and one program provider. The research data collection instrument was a questionnaire using Likert scale, and observation sheets. The reference to the assessment criteria used was the standard benchmark assessment. The results show that (1) the context aspect of the skill training program on processing cement waste paper is in the good category with the average score of 3,00 of the total score that has been set; (2) the input aspect of the skill training program on processing cement waste paper is in the good category with the average score of 2,59 of the total score that has been set; (3) the process aspect of the skill training program on processing cement waste paper is in the good category with the average score of 2,53 of the total score that has been set; and (4) the product aspect of the skill training program on processing cement waste paper is in the poor category with the average score of 2,06 of the total score that has been set.
Pelatihan literasi media digital bagi murid-murid armidale english college (AEC) di Soreang Kabupaten Bandung Selatan
Authors: Prasanti Ditha , Indriani Sri Seti
Published: July 2019

Kegiatan ini memiliki tujuan dapat menghasilkan luaran yaitu: (1) Memberikan pengetahuan dan wawasan yang konkret mengenai pelatihan literasi media digital; (2) Memberikan kemampuan dasar mengenai pelatihan literasi media digital bagi murid-murid AEC di Soreang Kab.Bandung Selatan. Metode pelaksanaan PKM yang dilakukan dalam kegiatan penyuluhan ini adalah metode ceramah; metode diskusi; dan metode kaji tindak. Kesimpulan dari pelatihan literasi media digital ini adalah: (1) Sebagai tolak ukur seberapa jauh murid-murid AEC mengetahui literasi media digital; (2) Meningkatkan kesadaran mereka akan pentingnya melek media digital berkaitan dengan segala informasi yang dianggap penting dalam media untuk generasi digital berikutnya; (3) Meningkatkan kemampuan dasar murid AEC tentang literasi media digital. Digital Media Literacy Training for Students Armidale English College (AEC) in Soreang, District of South Bandung AbstractThe activity is aimed at producing the following outputs: (1) Providing concrete knowledge and insight into digital media literacy training; (2) Providing basic skills on digital media literacy training for AEC students in Soreang Kab.Bandung Selatan. The method of PKM implementation conducted in this extension activity is the lecture method; Method of discussion; and action research method. The conclusions of this digital media literacy training are: (1) As a measure of how far AEC students know the digital media literacy; (2) Increasing their awareness of the importance of digital media literacy in relation to any information deemed important in the media for the next digital generation; (3) Improving the basic skills of AEC students about digital media literacy.
Penanaman sikap beragama dan moral anak usia dini di TKIT Salman Al Farisi 2
Authors: Khaironi Mulianah
Published: July 2019

Penelitian ini bertujuan untuk mendeskripsikan penanaman sikap beragama dan moral anak usia dini di TKIT Salman Al Farisi 2, meliputi: perencanaan pembelajaran, proses pembelajaran, pembiasaan di luar kelas, pihak yang berperan, dan aktivitas pendukung. Penelitian ini merupakan penelitian kualitatif studi kasus. Informan kunci guru dan orang tua. Pengumpulan data menggunakan observasi, wawancara mendalam, dan kajian dokumen. Hasil penelitian menunjukkan: (1) perencanaan pembelajaran berupa program semester, rencana pembelajaran program mingguan, dan rencana pelaksanaan pembelajaran harian; (2) langkah-langkah pembelajaran adalah  pijakan sebelum main, inti, dan penutup; (3) pembiasaan di luar kelas, seperti: mengucapkan salam, berjabat tangan, meminta maaf, membuang sampah pada tempatnya, saling menolong dan bersedekah; (4) pihak yang berperan adalah sekolah, orang tua, dan masyarakat sekitar (secara tidak langsung); (5) Aktivitas pendukung anak adalah kegiatan bakti sosial, manasik haji, kunjungan edukatif, kegiatan ekstrakurikuler, dan undang tokoh. Aktivitas pendukung guru adalah pembinaan akidah. Aktivitas pendukung orang tua adalah parenting dan sekolah orang tua salman. Inculcation religious and moral attitudes of early childhood in TKIT Salman Al Farisi 2 AbstractThis study was aimed to describe the inculcation of religious and moral attitudes of early childhood in TKIT Salman Al Farisi 2, including: the lesson plan, the learning process, the habituation outside the classroom, the participants, and the supporting activities. This study is a qualitative research using case study design. The key informants are teachers, and parents. The data were obtained observation, in depth interview, and document review. The results show that: 1) there are lesson plan in the form of semester learning plan, weekly learning plan, and daily learning plan; (2) the learning steps are done on a opening before play, core, and closing; (3) habituation outside the classroom are such as: greeting, shaking hands, apologizing, disposing of garbage in its place, helping each other and alms; (4) the participants are school, parents, and the surrounding community (indirectly); (5) there are supporting activities for children, such as social activities, rituals of hajj, educational visits, extracurricular activities, and invite characters. Supporting activities for teachers is namely the formation of teacher aqidah. Support activities for parents are namely parenting and salman parents school.