bluuebunny/crossref_metadata_2025 huggingface dataset:
Negative Pressure Wave Leakage Location Algorithm Based on Difference Cross-Correlation Delay Estimation
Authors: Zhao Lin , Wang Jiqiang , Hou Moyu , Li Zhen
Published: October 2019

Accurate estimate the time difference of the leakage negative pressure wave signals reached both sides of the sensor at the two sides of the leakage point is the key to accurate location of the leakage point. Based on the theoretical analysis of cross-correlation time delay estimation algorithm and characteristics of negative pressure wave signal, a cross-correlation delay estimation method for pipeline leakage negative pressure wave signal is proposed. Through wavelet transform, signal conversion and cross correlation function analysis of discrete negative pressure wave signal sequence obtained by high-speed sampling, the time difference of the negative pressure wave signal monitored by the sensors on both sides of the leakage point can be accurately obtained. In the laboratory’s 102.8 meters pipeline, leakage was simulated through the valve, the time delay estimation and leak location experiment of the sensor at the two ends of the pipeline were analyzed, and compared with the wavelet analysis method. The experimental results show under the condition that the leakage is 10%, 5% and 2% of the total pipeline volume, the cross-correlation analysis algorithm has a positioning error interval of 0.97%-1.46%, which is better than the current positioning error 0.48%-2.43% of the wavelet analysis algorithm. At the same time, it avoids the influence of different wavelet types and analysis scales in the wavelet analysis algorithm on positioning accuracy, and is more suitable for pipeline leakage monitoring system to real-time online monitoring needs, has a wide application value.
Research on Measurement and Control System of New Energy Vehicle Test Bench
Authors: Yuan Yongchao
Published: October 2019

New energy vehicles can alleviate the environment and energy pressure, promote the rapid upgrading and transformation of the automobile industry, and have a major impact on China’s technological economy and environmental improvement. However, at present, China’s new energy vehicle technology is still in its infancy, and there are still bottlenecks in the development of complete vehicles and parts. How to break through technical barriers and research new technologies has become a key factor in the introduction of new energy vehicles into the market. Based on this, the paper builds a new energy vehicle experimental platform, and develops a real-time online multi-channel data acquisition and analysis system based on Lab VIEW. Combined with the D2P Moto Hawk development platform, the electronic control of the test platform is realized. The final development of the measurement and control system enables dynamic monitoring of the test bench, fault alarms and control of key components.
A Characteristic Distill Arithmetic of Region Growing Method Based On Fuzzy Connectedness
Authors: Yang Yanli , Hui Xiachao , Zhang Jinsheng
Published: October 2019

To solve the problem that the traditional region growing algorithm cannot deal well with the fuzziness between the damage area and the background, and the segmentation result is sensititive to the initial seed pixel, a region growing method based on fuzzy connectedness is proposed. The method takes fuzzy connectedness as the similarity measure between the initial pixel and the growing pixel, which keeps the fuzziness among the pixels well. A growing crition integrated gray- fluctuation control with USAN area is proposed to fit the gray fluctuation in the damage area and get edge position precisely. The experiment results show the validation of this method.
The Research and Development of the Key Technologies for Runway Intrusion System
Authors: Zhang Liang
Published: October 2019

With the rapid development of the aviation market and the capacity limitations of aviation systems, runway intrusion has received increasing attention from the aviation community. Through the analysis of the possibility of runway incursions during the operation of Wuhan Tianhe International Airport, an algorithm for effectively preventing runway intrusion has been studied. Aiming at the many influencing factors of runway incursion, an improved runway intrusion algorithm has been proposed. Improved runway intrusion algorithm, applying flight performance and planning related knowledge to establish mathematical model, the physical properties of aircraft, such as type, wake, braking time, braking time after braking, as well as conflicting multiple zones, the slope of runway, pilot judgment reaction time, etc, these factors are all included in the consideration, so that the accuracy can be improved by setting different speed functions for different models. The simulation of the operation of the aircraft at Wuhan Tianhe International Airport has been carried out. The simulation results show that the model can give the alarm of runway intrusion and the reasonable solutions in time, which can effectively provide the assistants with decision-making.
Augmented reality tracking registration and process visualization method for large spacecraft cable assembly
Authors: Chen Huajun , Chen Changyu , Sun Gang , Wan Bile
Published: October 2019

The new generation of spacecraft has the characteristics of large-scale structure and complicated cable assembly process. In order to meet the needs of the augmented reality process visualization technology in its further application exploration, the two aspects of augmented reality tracking registration and process visualization are now studied. In the large-scale spacecraft cable assembly application scenario, the augmented reality process guidance technology puts more stringent requirements on the continuous tracking range and virtual and real registration accuracy of large space. The 3D process visualization method for cable assembly is optimized to improve the accuracy, quality and efficiency of the operator in process interpretation and implementation.
Auxiliary Error Correction Method for High Precision IMU
Authors: Gao Weiwei , Wang Hongyun , Fang Dan , Wang Yi , Zhang Hongyan , Zhang Xiaoliang
Published: October 2019

According to the needs of error correction about the low precision IMU strapdown calculation parameters, error correction method is researched under the high precision IMU, an error correction scheme is proposed, established the state space equation and the corresponding measurement equation, The simulation experiment is carried out in the state of motion carrier, The results show that the method is convergent to parameters of the estimation results, the attitude error, the accelerometer constant zero bias and the gyro zero bias is estimated effectively, the estimation accuracy of the attitude error can be achieved within one arc min. The method has high autonomy and strong anti-interference ability for the error correction of the low precision IMU, which is can be used in the case of the weapon system with multi precision inertial group.
Solving Flexible Job Shop Scheduling Problem in Cloud Manufacturing Environment Based on Improved Genetic Algorithm
Authors: Li Yunlong , Luo Guofu
Published: October 2019

In this paper, aiming at the new characteristics of flexible job shop scheduling in cloud manufacturing environment, this paper studies the residual capacity utilization of cloud manufacturing enterprises, considers the idle time of equipment, studies the workshop scheduling method with idle time, and constructs the scheduling framework of cloud manufacturing operation workshop. The production tasks accepted on the platform are carried out together with the tasks assigned by the workshop itself, with the goal of minimum penalty total cost, and the improved genetic algorithm is used to solve the optimal scheduling sequence of the workpiece. The validity of the proposed method is verified by using the benchmark example.
A Design of Solar Power Electric Zipper for Tent Based on Microcomputer STC89C52
Authors: Liu Yixian
Published: October 2019

This paper designs an electric zipper control system for outdoor tents, whose manually controlling zipper is laborious and time-consuming. The system adopts Microcontroller STC89C52 as the main control module. It can control the automatic opening and closing of the zipper according to the light intensity and the setting time. The device provides a solar power supply module to solve the problem of inconvenient charging in the field. The system has the advantages of high cost performance, stable operation, strong anti-interference, etc. It improves the shortcomings of the traditional intelligent zipper control.
Based on the comparison and analysis of the economic characteristics of transformers in an operating substation
Authors: Zhang Tianyi
Published: October 2019

The technical parameters of transformer are the basic data for analyzing and calculating the comparative analysis of transformer economic characteristics, The comparative analysis of transformer economic characteristics is to seek for reducing transformer active power and improving its operating efficiency, That is to reduce the transformer loss rate, And reduce the reactive power loss of the transformer. The active power loss, reactive power loss and integrated power loss of transformer are calculated. The quantitative calculation formula of economic operation mode of transformer in substation is obtained through analysis, The economic operation mode arrangement and load adjustment can be carried out for the transformer of a certain substation, The purpose of economic operation of transformer and reduction of network loss can be achieved.
Investment Attractiveness Evaluation on International Markets for Shengli Oilfied
Authors: Pan Fei , Zhang Zaixu , xie Jijun
Published: October 2019

In recent years, Shengli Oilfield continues to expand its international market for the aim of comprehensive, sustainable and high-quality development. This paper established an investment attractiveness evaluation index system (including 3 categories, 12 indicators) for the international markets and made a quantified evaluation of environmental risk in the five target markets including Middle East, Central Asia, North Africa, America and Southeast Asia. Based on the value of the investment attractiveness evaluation, this paper ranked the five target international markets and gives some further investment advices considering the current international strategy of Shengli Oilfield.
A Simulated Training Instrument for Testing Equipment
Authors: Wu Yong , Lei Lei , Zhang Jian Hu , Ruan XiaoYan , Zhang Jun
Published: October 2019

The number of certain testing equipment is small, and the teaching task undertaken by colleges and universities is heavy. The equipment works for a long time, which affects the training effect of teaching. To solve this problem, a simulator for testing equipment is developed. The simulator adopts modern technologies such as computer, automatic test, micro-electronics, automatic control and virtual instrument. It combines computer, target simulation, virtual instrument and data acquisition and processing to form a fully functional and cost-effective simulation maintenance training system.
Intelligent Music Rehabilitation Hand Based on Voice Recognition
Authors: Zhou Lingyi
Published: October 2019

Music therapy has its unique clinical application value in improving conscious state, emotional state, language communication ability, motion function, sleep state and the rehabilitation of the brain’s cognitive function of the patients who suffer from cerebral apoplexy and cerebral injury. With the rapid development of music rehabilitation therapy, it has become an important power in modern rehabilitation medicine, which is valued by rehabilitation workers. During rehabilitation training, the therapists, with the help of apparatuses, carry out hand technique and lower limbs training for the patients, or help them train by means of apparatuses. Rehabilitation equipment is a rehabilitation therapy facility widely used in the field of clinical care. At present, the existing rehabilitation equipment is mostly heavy, which makes the rehabilitation training dull and boring, and induces irritation of those receiving rehabilitation therapy through finger training to the disadvantage of the therapy. In the paper, an intelligent music rehabilitation hand is designed to help them for therapy at different stages. Different modes can be selected with voice interactive mode and control device. By using the theory of steering engine driving, the intelligent music rehabilitation hand can drive the steering engine with the rhythm of the music to achieve the aim of rehabilitation through driving the clenching and spreading of the fingers. With such a device, people can carry out their rehabilitation therapy while enjoying the music.
Power Consumption Analysis of Stepping Motor and Its Driving Circuit
Authors: Xie Aoru
Published: October 2019

In this paper the computer numerical calculation was used to analysis the power consumption of the stepper motor and the driver circuit and improve the efficiency. The mathematics model build with the parameter of 10PM-K013B has been calculated with different driving voltage and plus frequency, the relationship between efficiency and driving voltage, and between efficiency and plus frequency was obtained. The result showed that, the efficiency improved as driving voltage reduce and plus frequency rise. The efficiency can rise from 20% to 50% with appropriate choice of driving voltage and plus frequency.
Brief Analysis of the Impact of Green Building Materials on Ecological Environment
Authors: Li Xiaoqing , Yun Zhou
Published: October 2019

With the acceleration of urbanization construction and awareness of environmental protection, people’s demand for green building materials is increasing. Compared with traditional building materials with high consumption, high pollution and high cost, green building materials have incomparable performance, which is energy-saving, environmentally friendly and healthy. It has a positive impact on environmental protection. It is conducive to building a livable city, creating a beautiful homeland; reducing resource energy consumption and reducing environmental pollution; and building a resource-saving and environment-friendly society.
Information Security Risk Assessment of Hazardous Chemicals Emergency Command System Based on AHP-Fuzzy Comprehensive Evaluation Model
Authors: Zhang Jufeng , Gai Ke , Yang Fengfeng , Yang Rili , Wang Siyang
Published: October 2019

Emergency command system is the hub of dealing with emergencies, which is of great significance to emergency rescue. In order to establish a more perfect emergency command system, considering the characteristics of strong subjectivity and large error in qualitative evaluation of information security system, based on AHP (Analytic Hierarchy Process) and Fuzzy (Fuzzy Analysis) evaluation method, this paper uses AHP-Fuzzy comprehensive evaluation model to quantitatively evaluate the information security of emergency command system of a hazardous chemical production enterprise in Qingyang, and calculates the risk. The validity of the discriminant model is verified.
Thermal Simulation Analysis of Reliability of an Avionics Based on Flotherm
Authors: Tong Qin , Liang Jun
Published: October 2019

Aiming at the reliability thermal design of avionics equipment, based on the reliability thermal simulation and analysis method of flotherm, the CFD digital prototype is established. The thermal simulation and thermal test of avionics equipment model are carried out at room temperature, and the results of temperature data of both are compared. The error is less than 5% to verify the correctness of the model. The thermal simulation analysis of the high temperature 70 °C environment conditions is carried out by using the simulation model, and the latent heat dissipation problems and weak links of the components in the thermal design of avionics equipment are obtained. The location and cause of potential failure are pointed out to guide the thermal design of avionics equipment and improve the reliability of avionics equipment.
The Existing Problems and Promotion Strategies of Green and Low-carbon Urbanization in China
Authors: Song Haiyun , Zhang Xiaoxuan , Liang Cai , Zhang Xiaofeng
Published: October 2019

This paper analyzes the problems existing in the green and low-carbon development of urbanization in China from the perspectives of concept, planning and management, industrial structure, technological innovation and policy system, and proposes corresponding measures and Suggestions to promote the green and low-carbon development of urbanization.
Non-Mechanism Model for Superheater Pollution Diagnosis of Waste Incinerator Based on BP Neural Network
Authors: Li Maodong , Yang Bo , Zhai Wei , Ma Xiaoqian , Xia Yuqing , Lin Yan
Published: October 2019

Dust accumulation of boiler heating surface is one of the common problems in power plants, which will affect the unit’s economic and safe operation in serious cases. In this paper, the factors that affect the ash deposition in the superheater of the garbage incinerator are analyzed, and a non-mechanism model for diagnosing the ash deposition pollution in the superheater of the garbage incinerator is established by using 3-layer BP neural network. Parameters such as garbage disposal amount, furnace temperature, primary air flow amount and secondary air flow amount are selected as input vectors, parameters such as secondary superheater inlet smoke temperature and primary superheater inlet temperature are taken as output values, and real-time data of units collected by a power plant DCS system are used as sample sets to train the network after normalization processing. The trained BP network has good effect in superheater pollution diagnosis.
Research on Location Strategy of Mobile Anchor Node Based on Virtual Force
Authors: Chen Xuerui , Hu Yanzhu , Ai Xinbo , Shao Yanchao
Published: October 2019

In the process of wireless sensor network location based on mobile anchor nodes, the location strategy of mobile anchor nodes has important influence on the performance of positioning. However,the existing strategy does not traverse empty area effectively, the length of path is too long. Therefore, a dynamic adjustment location strategy based on virtual force is proposed. Firstly, the unknown nodes randomly distributed in the region are adjusted to be evenly distributed under the influence of virtual force. Then a moving anchor node travels from the positive center of the region along the direction of equidistant spiral and adjusts orientation dynamically under the influence of virtual force. The simulation results show that the anchor node can traverse effectively according to the unknown node’s distribution, and successfully shorten the length of moving path.
Study on Chitosan tetrasaccharide monomer Recognition System Based on Molecular Imprinting Technology
Authors: Li Meng , Meng Yingying , Zheng Yongjun
Published: October 2019

In this paper, we use chitosan as template molecule and N-[2-(dimethylamino) ethyl]-N’-[(2-hydroxy-4-vinylphenyl)] oxamide (H3eoxdmpe) as bridge ligand and directionally synthesize N-[2-(dimethylamino) ethyl]-N’-[(2-hydroxy-4-vinylphenyl)] oxamide dinuclear zinc-chitosan [Zn2 (eoxdmpe) (tetrachit)] (ClO4) coordination monomer. We study the interaction between complex and template molecules by ultraviolet spectrophotometry and the recognition ability of complex to monosaccharide molecule quantitatively by formula. The crystal structures of N-[2-(dimethylamino) ethyl]-N’-(2-hydroxy-4-vinylphenyl)] oxamide binuclear zinc-chitosan complex are determined and analyzed by X-ray single crystal diffractive technique and the results show that the metal coordination bond is a favorable binding activity for chitosan. This study provides an ideal model for the construction of metal coordination molecularly imprinted polymers which are selectively recognized by chitosan.
Environmental Protection Responsibility of Enterprises: Green Human Resource Management
Authors: Zhang Bei
Published: October 2019

In recent years, with environmental problems such as climate warming and air pollution becoming more and more prominent, more and more attention has been paid to the sustainable development of enterprises from all walks of life in the world. Therefore, the concept of green human resources management has been put forward by relevant experts. This paper mainly reviews the existing literature on green human resource management. Starting from the formation of the conceptual meaning, this paper explores the inevitability and results of the theory’s emergence and development sums up the practice of green human resources management in enterprises in recent years, including recruitment and selection, training and development, performance pay, employee relations, and looks forward to the future research direction of green human resources management.
Study on Road Safety Design for Urban Disaster Prevention and Refuge
Authors: Qin Yan , Xue Luo
Published: October 2019

Urban disaster prevention and refuge road is the primary evacuation and rescue passageway space when the disaster happens. The safety design of urban road for disaster prevention and refuge can guarantee the safety rescue, evacuation and escape. As the lifeline system of disaster prevention and relief, the urban disaster prevention and relief road supported the carrier of people and materials movement during the disaster, and was the life channel to maintain the normal operation of the city during the disaster. It played an important role in the disaster prevention and reduction system.
New Development of Environmental Pollution Criminal Justice: Starting With the Summary of the Symposium on Criminal Cases of Environmental Pollution in 2019
Authors: Zhang Junying
Published: October 2019

The Summary of the Symposium on Criminal Cases of Environmental Pollution in 2019 has important normative and guiding significance for criminal justice of environmental pollution, further clarifies the judicial concept of recognizing the objective elements of environmental pollution by carrying out the protection purpose of ecological legal interests, clearly identifies the subjective fault of environmental pollution based on responsibility doctrine and the attempt of dealing with environmental pollution based on objectivism. Criminal forms, based on the actual results of environmental pollution to deal with environmental pollution related to illegal business and the release of dangerous substances and other criminal cooperation phenomenon.
Research on Simulation and Analysis of Monitoring Process of Hail-proof Apple Bagging Four-rotor Aircraft
Authors: Gou Xiaoping , Zhang Wanjun , Zhang Jingxuan , Zhang Jingyi , Zhang Jingyan
Published: October 2019

This bagging method is feasible and can produce strong economic and social benefits, and is recognized by the majority of fruit farmers. With the frequent occurrence of natural disasters in recent years, search and rescue equipment of four-rotor aircraft has been widely used. Firstly, the overall design architecture of the four-rotor flight system is introduced. Then the dynamic model of the four-axis aircraft is established for the ground coordinate system and the collective coordinate system. At the same time, the response speed, control stability, and robustness are obtained. The control algorithm of aircraft is designed by using sliding mode variable structure control theory. Finally, the simulation data is used to compare the controller with the controller, and it is proved that the controller’s strength and stability meet the requirements of the project.
Research on Theories and Methods of Vehicle Sound Source Recognition
Authors: Xiong Jianqiang
Published: October 2019

In this paper, the theory of vehicle noise source identification is studied and analyzed, based on the theory of various noise sources identification, the theory of vehicle noise source identification is divided into traditional noise source identification method, signal analysis-based noise source identification method and visualization-based noise source identification method. The basic principle, process, advantages and disadvantages of the three kinds of noise source identification theory described in this paper, as well as the application and selection analysis of the suitable situation are mainly described. Finally, it is pointed out that the application of visualization technology will be the main development trend of vehicle noise source identification theory.
Study on the Ways of Training Undergraduates’ Employment Ability under the Mode of Low Carbon Economy Development
Authors: Sun Xu , Yang Yang , Lv Xing
Published: October 2019

The development and employment of low-carbon economy is the two hot issues of concern in today’s society. The development of low-carbon economy has promoted the adjustment of industrial structure, which in turn affects the employment structure and has an important impact on employment. At the same time, employment in turn affects the industry. The structural changes promote the development of low-carbon economy to a certain extent, and the mutual influence of each other promotes each other. The interaction between college students as a special group of employment and low-carbon economic development is more significant. The state should actively adopt policy support and technological innovation. Measures such as industrial upgrading, personnel training, environmental construction, and establishment of mechanisms promote synergistic development and benign interaction between the two, so as to better promote the sound and rapid development of the social economy, effectively solve the employment problems of college students, and promote the comprehensive and coordinated social and human and sustainable development.
Research on Blockchain Technology in Promoting Environmental Protection Development of Agricultural Products E-commerce Model in Jilin Province
Authors: Zhan Hui , Lv Xing , Xu Dan
Published: October 2019

With the continuous maturity of its technology and philosophy, the blockchain has officially entered the 3.0 phase, which is characterized by a programmable society. That is, the blockchain will gradually penetrate from the virtual world to all aspects of real life, and the agricultural product e-commerce is now the stage connects real and virtual best opportunities. Blockchain is another wave of information technology revolution after the Internet, mobile Internet, and cloud computing and big data platform. Blockchain technology has decentralized, de-intermediary trust, security and confidentiality functions, which have been applied in banks. Securities, insurance, payment, agricultural products exchange and other fields. Jilin Province is a major province for the production and export of agricultural products. How to promote the development of agricultural products e-commerce in the region towards a more environmentally friendly and energy-saving direction is a problem that scholars in the field should ponder. Based on this, this paper expounds the characteristics and application of blockchain, discusses the application of blockchain technology in the agricultural product e-commerce industry in Jilin Province, and combines the characteristics of C2M mode to give a blockchain decentralization and Design case for trust and security mechanisms.
Research on the Impact of Traffic Information Coverage Rate on Traffic Congestion
Authors: Song Zhuo , Wang Fujun
Published: October 2019

With the vigorous development of technologies such as the Internet, Internet of Things, and cloud computing, terms such as “car networking” and “intelligent transport” have gradually appeared in people’s field of vision. Traffic information has become more and more timely and comprehensive, which has gradually improved the transportation system. From the perspective of traffic participants’ knowledge of information, this paper studies the impact of traffic information coverage on traffic congestion. First, the author established a mathematical model based on optimization theory. Then through simulation, the author simulates the traffic congestion situation in different scenarios (traffic participants have different information), and then obtains the following conclusions: Traffic participants who are completely random or choose their path according to their own preferences will affect road traffic efficiency and cause traffic congestion. In addition, the traffic information coverage rate is not as high as possible, but there is an optimal coverage rate. Finally, through the analysis of the Sancha Road network system, the author has obtained the following conclusion: It is a reasonable situation to set 73% of traffic participants’ information transparency, that is, the information coverage rate is 73%.
Distributed Denial of Service Attacks and Defense Mechanisms
Authors: Tang Dan , Kuang Xiaohong
Published: October 2019

Distributed denial-of-service (DDoS) attacks have become a common problem in networked environments. The large number of variations in both the types of DDoS attacks and their mitigating approaches are an apt indicator of the extent of the issue. This article will offer an analysis of the existing DDoS attacks and their corresponding countermeasures. The paper aims to highlight the strengths and weaknesses of the available defenses in order to demonstrate the degree of applicability and efficiency of the solution methodologies. To achieve these objectives, the paper assumes a systematic design whereby it evaluates the DDoS attacks according to similar attributes, which in turn informs the evaluation of defense tactics.
Application of Models for Occupational Health Risk Assessment to a Resin Anchorage Production Workshop
Authors: Qu Wei , Feng Bin , Zhang Limei , Zhang Haidong , Zhang Pu , Wang Hui , Lin Geng , Wang Rui
Published: October 2019

Objective to take the occupational health risk assessment in a resin anchorage production workshop by three models for occupational health risk assessment, and explore a suitable risk assessment model for this kind of production unit. Methods the occupational health status and main chemical hazard factors of a resin anchorage production workshop were investigated. Qualitative risk assessment and semi-quantitative risk assessment (contact limit ratio method and comprehensive index method) were used for risk assessment, and the results were compared and analysed. Results Comparing with comprehensive index method, the evaluation result of qualitative risk assessment and contact ratio method were closer to each other, but there was a big difference between the two methods in the determination of phthalic anhydride. Conclusion the three risk assessment methods had their own merits and demerits, the evaluation results were also different. The semi-quantitative risk assessment-contact limit ratio method is more suitable for the occupational risk assessment in resin anchorage production workshop.
Review on Research process of Sound reduction Materials
Authors: Chen Wei , Hu Sheng , Cao Hao , Huang Tao , Wu Xiaowen , Lu Ling , Peng Jiwen
Published: October 2019

Noise pollution, air pollution, water pollution and solid waste pollution are recognized as four major environmental pollution sources in the world. Based on the principle of noise reduction, noise reduction materials mainly include sound absorbing material, sound insulation material and noise damping material. In this paper, the mechanism, research progress and development trends of the three kinds noise reduction materials are reviewed and discussed.
Image Automatic Counting Method by Using Deep Transfer Learning
Authors: Huang Shasha , Sun Ke , Hu Guoxing , Qiao Jia
Published: October 2019

In view of the narrow long room, fast speed and roll sport while outside the room, single camera couldn’t achieve the measurement of big cargo extraction. This paper puts forward an intersection measurement system of multiple ultra-short focus cameras and high-speed cameras. The system can achieve the parameters of wholly sport process by measuring the marked points on cargo, coordinate conversion and data registration. Measurement data show the trajectory and attitude parameters truly. Measurement precision satisfies the requirement of subject.
Node Reputation-Based Replica Replication Strategy in P2P Networks
Authors: Zhu Yongqiong
Published: October 2019

Replica technology increases the reliability and availability of data by increasing the redundancy of data in the system. The existing replica replication algorithm only depends on the access traffic of the node when selecting the replication node, ignoring the non-cooperation of the node, resulting in a decrease in the utilization of the replica. This paper proposes an adaptive replica management policy PCA based on node reputation. PCA selects nodes with large query traffic and high reputation as replication nodes to ensure high query hit rate. Because PCA sets the copy according to the cooperation of the node, it avoids the waste of copy caused by setting the copy on the non-cooperative node, and guarantees high copy utilization.
Research on Decoupling of China’s Logistics Demand and Energy Consumption Carbon Emission
Authors: Liu Lian
Published: October 2019

At present, China pays more and more attention to the development of green logistics, while the logistics industry is still in the stage of extensive development, deviating from the green, low-carbon and efficient development concept. Therefore, the analysis of the characteristics of energy consumption and carbon emissions in the logistics industry has important theoretical and practical significance for the formulation of effective energy-saving and emission reduction strategies. Using the carbon emission coefficient method to calculate the logistics industry carbon emissions, and using the decoupling theory to analyze the correlation between the logistics freight volume and the logistics industry energy consumption and carbon emissions.The results show that China’s logistics industry is trying to change the development mode, adapt to the impact of policy and economic environment.So as to adapt to the needs of the logistics market, logistics industry gradually transform to the complex industry.
RAACBook: a web server of reduced amino acid alphabet for sequence-dependent inference by using Chou’s five-step rule
Authors: Zheng Lei , Huang Shenghui , Mu Nengjiang , Zhang Haoyue , Zhang Jiayu , Chang Yu , Yang Lei , Zuo Yongchun
Published: October 2019

By reducing amino acid alphabet, the protein complexity can be significantly simplified, which could improve computational efficiency, decrease information redundancy and reduce chance of overfitting. Although some reduced alphabets have been proposed, different classification rules could produce distinctive results for protein sequence analysis. Thus, it is urgent to construct a systematical frame for reduced alphabets. In this work, we constructed a comprehensive web server called RAACBook for protein sequence analysis and machine learning application by integrating reduction alphabets. The web server contains three parts: (i) 74 types of reduced amino acid alphabet were manually extracted to generate 673 reduced amino acid clusters (RAACs) for dealing with unique protein problems. It is easy for users to select desired RAACs from a multilayer browser tool. (ii) An online tool was developed to analyze primary sequence of protein. The tool could produce K-tuple reduced amino acid composition by defining three correlation parameters (K-tuple, g-gap, λ-correlation). The results are visualized as sequence alignment, mergence of RAA composition, feature distribution and logo of reduced sequence. (iii) The machine learning server is provided to train the model of protein classification based on K-tuple RAAC. The optimal model could be selected according to the evaluation indexes (ROC, AUC, MCC, etc.). In conclusion, RAACBook presents a powerful and user-friendly service in protein sequence analysis and computational proteomics. RAACBook can be freely available at http://bioinfor.imu.edu.cn/raacbook.

Database URL: http://bioinfor.imu.edu.cn/raacbook
3044Exploration of biomarkers for subclinical atherosclerosis in an African population using a proteomics chip targeted at inflammation and cardiovascular disease
Authors: Jujic A , Malan L , Mels C , Nilsson P M , Magnusson M
Published: October 2019

Introduction

The evolving use of multiplex proteomic platforms provides an excellent tool for investigating associations between multiple proteins and subclinical atherosclerotic disease. In this study, we evaluated the impact of a multiplex protein panel, on carotid intima-media thickness (cIMT) as a marker of subclinical atherosclerosis.

Purpose

We used a multiplex proteomic platform to identify possible associations between proteins and subclinical carotid atherosclerosis as measured by carotid ultrasound in an African population.

Methods

In the Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA) study, 92 proteins from the Proseek Multiplex CVD III 96×96 (Olink Bioscience, Sweden) were analyzed in 378 participants (mean age 44.7±9.6 years, 50.6% women, 10.8% with known cardiovascular disease). Carotid ultrasound was performed for measurements of the carotid intima-media thickness (cIMT, mean 0.663±0.127 mm) and calculation of cross-sectional wall area (CSWA, mean 13.5±4.4mm2), a measure of target organ damage. Possible associations between the proteins, and cIMT and CSWA, respectively, were explored using linear regression models. A two-sided Bonferroni corrected P-value of 0.05/92=5.4x10–4 was considered statistically significant in the crude analysis.

Results

Of 18 proteins (1 standard deviation of change of ln-transformed values) that were Bonferroni-corrected (p≤5.4x10–4) significantly associated with cIMT and/or CWAS in crude analyses, the following remained significant after further adjustment for age, sex, waist circumference, systolic blood pressure, smoking and total cholesterol: growth-differentiation factor-15 (GDF15; β 0.017, p=0.050), E-selectin (SELE; β 0.019, p=0.017), carboxypeptidase A1 (CPA1; β 0.019, p=0.019), C-C motif chemokine 15 (CCL15; β 0.031, p<0.001), chitinase-3-like protein 1 (CHI3L1; β 0.021, p=0.007), the hemoglobin scavenger receptor (CD163; β 0.021, p=0.008) and osteoprotegerin (OPG; β 0.022, p=0.004). As for target-organ damage defined by CSWA, SELE (β 0.459, p=0.018), CCL15 (β 0.398; p=0.032) and CD163 (β 0.541, p=0.005) showed multivariate adjusted significant associations.

Conclusion

In an African population, we could confirm five proteins (GDF15, SELE, CHI3L1, CD163 and OPG) associated with cIMT, but in addition identified two proteins (CPA1 and CCL15) with novel associations with cIMT and/or CSWA.

Acknowledgement/Funding

North-West University; National Research Foundation (NRF); Medical Research Council (MRC-SA); Department of Education North-West Province; ROCHE
3048PARADIGM-Extend prospective academic trial: Accumulating long-term evidence for MicroNet-covered stent safety and stroke prevention efficacy
Authors: Musialek P , Mazurek A , Trystula M , Borratynska A , Tomaszewski T , Lesniak-Sobelga A , Brozda M , Gancarczyk U , Dluzniewska N , Urbanczyk M , Banys R P , Judzialo P , Drazkiewicz T , Partyka L , Podolec P
Published: October 2019

Aims

To provide long-term clinical (incl neurologic) and duplex ultrasound (DUS) evaluation of the CGuard MicroNet-covered embolic prevention stent system (EPS) routine use to perform CAS in all-comer (no exclusion criteria) patients with symptomatic or increased-stroke-risk asymptomatic carotid stenosis recommended for revascularization by the NeuroVascular Team.

Methods and results

PARADIGM-Extend is a non-industry-funded, prospective academic study in all-referrals-tracked symptomatic and asymptomatic carotid stenosis. In asymptomatic lesions, intervention is mandated only in case of increased-stroke-risk features. There is first-line consideration to use the study device, with EPD choice according to tailored-CAS algorithm. Independent neurologist evaluation and DUS are performed before CAS, at 48h, 30 days, and then every 12 months. There is external source data verification, external angiographic corelab, and external statistical analysis. Currently 325 patients (48–87 years, 54.2% symptomatic) crossed the 1st follow-up window. There has been 100% CGuardEPS use. Angiographic DS was reduced from 84±8% to only 6.9±5% (p<0.001, “CEA-like” effect of CAS).

Peri-procedural death or major stroke rate was 0%. One event was CEC-adjudicated as minor stroke (0.3%), and there was one (type2) MI (0.3%). By 30 days there was one haemorrhagic transformation leading to death (0.3%) and one bleeding-related death (0.3%). Thus total death/major stroke/minor stroke rate at 30 days was 0.9%, and total death/major stroke/minor stroke/MI rate at 30 days was 1.2%. At 1- 12 months were no strokes or stroke-related deaths (0%). At 12–24 months there was one cerebellar stroke in an AFib patient that was confirmed on MRI imaging but no carotid-territory stroke or stroke deaths (0%). By 24 and 36 months there was one posterior circulation (cerebellal) infarct but no cerebral infarctions. Post-procedural in-stent velocities were normal and remained normal throughout the 36-month follow-up period (peak-systolic/end-diastolic velocity 0.69±0.29/0.18±0.09 m/s at 30 days, 0.82±0.47/0.22±0.13m/s at 12 months, 0.73±0.31/0.19±0.09m/s at 24months and 0.80±0.31/0.21±0.11 at 24months), indicating normal device healing.

Conclusions

PARADIGM-Extend accumulating 36-month clinical and DUS evidence is consistent with unprecedented, sustained safety and cerebral embolism prevention efficacy of the CGuard™ MicroNET-covered embolic prevention stent system used routinely for stroke prevention in symptomatic and increased-stroke-risk asymptomatic subjects with carotid stenosis.

Acknowledgement/Funding

K/ZDS/007819 Jagiellonian University Medical College
3073Leveraging transcriptome sequencing for detecting novel disease-related pathways using human cardiac sarcoidosis myocardium biopsies
Authors: Yoshida S , Nomura A , Tada H , Sakata K , Nakanishi C , Fujino N , Hosomichi K , Tajima A , Takamura M
Published: October 2019

Background/Introduction

Cardiac sarcoidosis (CS) is one of the main causes of poor outcomes in patients with sarcoidosis, a systemic granulomatous disorder of complex etiology including a genetically susceptible host and specific exposure to disease-triggering antigens. Recently, transcriptome analysis using sarcoidosis peripheral monocytes was reported to be useful for exploring genetic susceptibility and novel disease-causing pathways. However, transcriptome sequencing has not been used to explore disease-related genes and pathways directly using human CS myocardial biopsies.

Purpose

This study aimed to identify transcriptome profiles and novel disease-related pathways of CS by comparing human CS myocardial biopsies with control samples using ribonucleic acid (RNA) sequencing (RNA-Seq).

Methods

We assessed 30 patients with suspected myocardial disorders who underwent transcatheter endomyocardial biopsies at our University Hospital, Japan. Of those, 7 were clinically diagnosed with CS, 9 with hypertrophic cardiomyopathy (HCM), and 14 with dilated cardiomyopathy (DCM). Messenger RNAs were extracted from cardiac muscle biopsies using the Ovation SoLo RNA-Seq System (NuGEN Technologies), according to the manufacturer's instructions. Sequencing was performed with coverage of approximately 20 million reads per sample using Illumina HiSeq 2000. Sequencing reads were mapped using the STAR 2-pass method with GRCh37 as the reference. The DESeq2 R package (version 3.8) was used for further analyses. Principal component analysis (PCA) on gene expression was conducted for detecting outliers such as non-muscular samples. Differential gene expression analysis was performed between the 7 patients with CS and 23 patients with cardiomyopathy (HCM and DCM, non-CS). Gene Ontology (GO) enrichment analysis was conducted to estimate possible disease-related pathways.

Results

We successfully sequenced 60 myocardial biopsy samples (original and biological duplicates) from 30 CS patients. Of these, 2 outlier samples shown by the PCA plot were removed, and 58 were used for further analyses. We found 243 genes that were differentially expressed between CS patients and non-CS patients. Top-rated genes were RP11–366M4.8, RELN, S100A6, WASF3and UCHL1. Pathway analysis using GO demonstrated enrichment oflymphocyte activation (P=4.8x10–16), organelle fission (P=6.1x10–14), the M phase of the mitotic cell cycle (P=2.2x10–13), nuclear division (P=2.4x10–13), mitosis (P=2.4x10–13) and T-cell activation pathways (P=1.2x10–12).

Conclusions

Our differential gene expression and pathway analysis results using human CS myocardial biopsies suggested that lymphocyte activation, specifically the T-cell activation pathway, is linked to CS pathogenesis. Further studies are needed to decipher the role of specific genes related to genetic susceptibility and/or pathways associated with CS occurrence.
3151The prognostic meaning of a reduced reserve of left ventricular force during exercise in hypertrophic cardiomyopathy
Authors: D'Alfonso M G , Peteiro J , De Azevedo Bellagamba C C , Torres M A R , Re F , Tesic M , Monserrat L , Djordjevic-Dikic A , Beleslin B , Fernandez X , Cotrim C , Olivotto J , Ciampi Q , Mori F , Picano E
Published: October 2019

Background

Hypertrophic cardiomyopathy (HCM) patients with blunted force-frequency relationship assessed with pacing during cardiac catheterization are at greater risk of adverse events. Left ventricular contractile reserve (LVCR) based on force can be obtained noninvasively during exercise stress echocardiography (ESE).

Purpose

To evaluate the prognostic correlates of force-based LVCR during ESE in HCM.

Methods

We enrolled 332 HCM patients (age 51±15 years, 193 males, New York Heart Association, NYHA, Class I-III, EF 68±9%, maximal wall thickness 20±5 mm, left ventricular outflow tract gradient, LVOTG, present at rest in 34 pts, 10%) referred for ESE in 7 quality-controlled labs. SE assessment included LVOTG (mm Hg), LV Force (systolic blood pressure by cuff sphygmomanometer + LVOTG/LV end-systolic volume assessed with 2-D, mmHg/ml) and LVCR (peak/rest ratio of LV Force). LV volumes were measured from apical biplane (4- and 2-chamber) views with Simpson method when feasible (n=290) or with linear Teichholz (T) method from parasternal (long- or short-axis) view (n=42). All patients were followed-up.

Results

Force values were 8.5±6.7 at rest and 15.0±13.7 mmHg/mL at peak stress (P<0.001). During a median follow-up time of 58 months, 50 patients experienced at least one event: 19 deaths (10 cardiac), 9 hospitalizations for acute heart failure, 16 myotomy/myectomy and 22 atrial fibrillations. The event-free survival was lower in the 195 patients with LVCR <1.77 (identified with Receiver-Operator Characteristic analysis) compared to the 137 with LVCR ≥1.77: see figure. Multivariate analysis identified LVCR (Hazard ratio, HR, 2.032, 95% confidence intervals, CI, 1.042–3.964, P=0.037), age (HR, 1.033, 95% CI 1.009–1.058, P=0.007) and NYHA class (HR 2.204, 95% CI 1.161–4.185, P<0.016) as independent predictors of events.

Figure 1. HCM-LVCR

Conclusion

A non-invasive evaluation of LVOTG, systolic blood pressure and LV end-systolic volume during ESE allows to assess force-based LVCR in HCM. Lower LVCR is associated with greater risk of events at follow-up.