bluuebunny/crossref_metadata_2025 huggingface dataset:
Computational study of characteristics of intake flow in model axial compressor with regard to different variants of “active disk” boundary condition
Authors: Voronich I.V. , Nguyen V.H.
Published: May 2019

Aerodynamic interaction between the compressor (fan) and the air intake is a characteristic feature of modern turbojet engines of civil aviation. An approach based on unsteady three-dimensional modeling of the flow taking into account full blade rows is necessary for analysis but is too resource-intensive for design. In some cases, an approach based on the “active disk” boundary condition can be successfully used to analyze aerodynamic interference of the engine with airframe elements. In the present work, the flow characteristics in the air intake of a model axial compressor JT8D are studied and different variants of the “active disk” boundary condition that can replace the compressor in the air intake are compared. The results of the computational study of characteristics of the axial compressor model in nacelle based on a pre-validated technique are presented. An analysis of integral characteristics and profiles of variables in different cross-sections at rotational speeds constituting 70, 80 and 90 % of the design value is performed. The results obtained using different variants of the “active disk” boundary condition are compared, and a preferred variant is selected. For the configuration in question, the method has proven to be efficient and accurate.
I Know What I Do Not Know: Toward the Reflective Elementary Classroom
Authors: Zuckerman Galina A.
Published: May 2019

Mastering the ability for learning to learn is the most ambitious goal of modern educators. A distinction is made between two relatively independent components of this expertise: (a) the reflective component of the learning to learn ability that allows a person comprehend what knowledge and skills he or she lacks to act in the new situation; (b) the search component of the learning to learn ability that allows the learner to find the missing knowledge and appropriate it. The article deals with the reflective component of the ability to learn and the method to develop it within the El'konin–Davydov system of school education. This system has grown from the hypothesis that reflective thinking belongs to the zone of proximal development of children starting school. Within this system, psychological tools are developed for fostering those reflective potentials of the human mind that are left neglected or even suppressed under the school system prevailing today. Psychological and educational means of developing reflection in class are illustrated through the clinical analysis of dialogs on a math lesson in the first grade. The developmental outcomes of the El'konin–Davydov educational system are exemplified using the cases of tasks with missing data. By the diagnostical assessment of the forth graders, we have confirmed that when the content of education is radically changed, the reflective components of the ability to learn can be successfully developed as early as in the elementary school.
Starševski stres in kakovost življenja družine otroka z obporodno hipoksijo, zdravljeno s hipotermijo
Authors: Rančigaj Gajšek Manja , Derganc Metka
Published: May 2019

Preučevali smo kakovost življenja ter količino starševskega stresa pri družinah otrok s hipoksično ishemično encefalopatijo (HIE), zdravljeno s terapevtsko hipotermijo (TH). Starši 19 otrok (10 otrok z blago, 6 z zmerno in 3 s hudo HIE), starih od 6;0 do 9;4 let, so izpolnili vprašalnika PedsQL-FIM in PSI-III. Kot merilo razvojnega izida smo otrokom izmerili količnik inteligentnosti (IQ) z instrumentoma WISC-IIISI oziroma WPPSI-IIISI. Kakovost življenja družin je bila v povprečju višja, starševski stres pa v območju povprečja glede na splošno populacijo. Družine so se v večini prilagodile dejavnikom tveganja za porušeno delovanje družine, ki jih prinaša otrokova bolezen, kar je skladno s teorijo o pozitivni prilagoditvi (dvojni ABC-X model). Tako kot v predhodnih raziskavah, ki so vključevale družine otrok s HIE in z nekaterimi drugimi kroničnimi boleznimi, smo v družinah otrok s podpovprečnim IQ ugotovili slabšo kakovost življenja družine in povišan starševski stres na nekaterih (ne pa vseh) področjih v primerjavi z družinami otrok s povprečnim ali nadpovprečnim IQ. Otrok s HIE, zdravljenih s TH, ne moremo obravnavati kot homogeno skupino, saj so razvojni izidi otrok različni, prav tako so specifične tudi značilnosti in potrebe otrok in njihovih družin. Starši so pogosto izpostavljali negotovost in strah, ki so ju doživljali po rojstvu otroka – ob diagnozi in akutnem zdravljenju otroka, zato se je pri raziskovanju delovanja družine smiselno usmeriti na zgodnje obdobje. Zdravstveni delavci morajo starše usmerjati k virom pomoči v lokalnem okolju, prav tako pa k tistim na državni ravni. Za starše sta pomembna pridobivanje informacij o naravi otrokovih težav in možnih oblikah pomoči, pa tudi strokovna terapevtska pomoč, kadar je to potrebno. Za nudenje optimalne podpore družinam kronično bolnih otrok je bistvena podpora zdravstvene in socialne politike.
Contra Negativity in Religious Language
Authors: Cardwell David
Published: May 2019

An investigation into the general phenomenon of "negativism" i.e., unjustifiable doubt especially as highlighted in the history of scientific discoveries, showing its reality, and suggesting its possible causes. An examination of negativism in the realm of theology. A possible way forward, principally through a justification of certain assertions as "religio-synthetic", being either religio-forensic (relating to past history as recorded in Old and New Testament accounts) or religio-scientific (relating to case-histories of clinical theology which offer well-attested accounts of healings, fulfilled prophecies, and spiritual and moral regenerations).
Social Entrepreneurship in the Conduct of Responsible Innovation: Analysis Cluster in Mexican SMEs
Authors: Bahena-Álvarez Irene Liliana , Cordón-Pozo Eulogio , Delgado-Cruz Alejandro
Published: May 2019

Responsible innovation combines philanthropic and economic aspects and it is common to refer to entrepreneurs who lead it as "social entrepreneurs". The present study of 100 Mexican SMEs, provides knowledge of exploratory nature about what the models of organization are conducive to SMEs in the generation and development of responsible innovations. Through the statistical technique of cluster analysis, this study identified and characterized four models of organization according to the level of social entrepreneurship reached: (1) “The techno-scientific organization”, (2) “The techno-social organization”, (3) “The capitalist-social organization” and (4) “The capitalist organization”. While in Europe the dominant discourse about responsible innovation focuses on the control of the risk of social rejection of the advance of science and technology; in contexts such as the Mexican, the phenomenon is configured as the mechanism through which entrepreneurs articulate its technological and scientific capabilities to solve priority and specific problems of the society, however, the social impact does not crucially affect their business initiatives. The techno-scientific organization (50% of studied SMEs) is proposed as the model of organization with greater viability for Mexican entrepreneurs.
Force Prevalence Analysis
Authors: Schaller Alex
Published: May 2019

The electric field is enormously more powerful than the gravitational field. However, in our normal experience there is no electric field, the electric force is missing. How is it that when you get to larger and larger scales the gravitational field is extremely important whereas the electric field becomes less and less important [1]? This paper proposes a model to explain why gravitation dominates at a larger scale.
Identifying Human Behavious Using Deep Trajectory Descriptors
Authors: Ali Tauseef , Alreshidi Eissa
Published: May 2019

Identifying human actions in complex scenes is widely considered as a challenging research problem due to the unpredictable behaviors and variation of appearances and postures. For extracting variations in motion and postures, trajectories provide meaningful way. However, simple trajectories are normally represented by vector of spatial coordinates. In order to identify human actions, we must exploit structural relationship between different trajectories. In this paper, we propose a method that divides the video into N number of segments and then for each segment we extract trajectories. We then compute trajectory descriptor for each segment which capture the structural relationship among different trajectories in the video segment. For trajectory descriptor, we project all extracted trajectories on the canvas. This will result in texture image which can store the relative motion and structural relationship among the trajectories. We then train Convolution Neural Network (CNN) to capture and learn the representation from dense trajectories. . Experimental results shows that our proposed method out performs state of the art methods by 90.01% on benchmark data set.
Neuropsin in Mental Health
Authors: Bukowski Lina , Chernomorchenko Ana , Starnawska Anna , Staunstrup Nicklas , Qvist Per , Børglum Anders
Published: May 2019

Neuropsin is an extracellular matrix serine protease that governs the proteolytic cleavage of synaptic proteins and consequently synaptic structural plasticity. In the brain, its substrates include the cell adhesion molecules Neuregulin-1 and L1CAM, that have been linked to neurodevelopmental processes and disorders, such as schizophrenia and bipolar disorder. Neuropsin mRNA is abundant in the cerebellum and several peripheral tissues from mid-gestation but is mainly expressed in cortical and limbic tissues postnatally. Differential usage of neuropsin splice forms in the fetal and adult brain has only been reported in humans, suggesting that neuropsin may serve a specialized role in human neurodevelopment. Accordingly, both the expression and proteolytic activity of neuropsin are subject to regulation by neural activity as well as by environmental risk factors associated with mental illness, such as psychophysiological stress. Intriguingly, dysregulation of neuropsin has been reported in depression and Alzheimer’s disease and its implication in mental disorder is supported by genetic and epigenome wide studies. Here we review neuropsin regulation in mental health and provide a summary of clinical and preclinical evidence supporting a role for neuropsin in the pathogenesis of mental disorders.
Comparison of anterior segment changes after femtosecond laser LASIK and SMILE using a dual rotating Scheimpflug analyzer
Authors: Kim Bu Ki , Mun Su Joung , Yang Young Hoon , Kim Ji Sun , Moon Jun Hyung , Chung Young Taek
Published: May 2019

Purpose

To compare the changes in the anterior segment after femtosecond laser in situ keratomileusis (FS-LASIK) and small incision lenticule extraction (SMILE) using a dual rotating Scheimpflug (DRS) analyzer (Galilei®; Ziemer Ophthalmology, Port, Switzerland).

Setting

Onnuri smile eye clinic, Seoul, South Korea

Design

Retrospective

Method

218 eyes of 109 patients who underwent FS-LASIK or SMILE for myopic correction were retrospectively studied. Ninety-eight eyes of 49 patients who underwent FS-LASIK were compared to 120 eyes of 60 patients treated with SMILE. A DRS analyzer was used for preoperative and 6-month postoperative anterior segment analyses. Measured variables included the central corneal thickness (CCT), anterior chamber depth (ACD), anterior and posterior keratometry (K), anterior and posterior best-fit sphere radius, and maximum posterior elevation (MPE).

Results

The estimated lenticule thickness (LT; 87.20 ± 22.87 µm) was significantly thicker in the SMILE group than the ablation depth (69.23 ± 22.24 µm) in the FS-LASIK group. However, there was no significant difference in the CCT decrease using the DRS analyzer. The MPE was significantly increased after both procedures, and there was a statistically significant difference in the change in MPE between the two groups (-1.10 ± 2.12 µm after FS-LASIK; -0.75 ± 2.33 µm after SMILE; p = 0.035).

Conclusions

The preoperative LT was overestimated using SMILE. Regarding changes in the MPE and posterior K, changes in the posterior corneal surface were greater after FS-LASIK than after SMILE.
The efficacy and safety of Ojeok-san plus Saengmaek-san for gastro-esophageal reflux-induced chronic cough: a protocol for a pilot, randomized, double-blind, placebo-controlled trial
Authors: Bhang Yeon Hee , Kim Kwan-Il , Kim Jaehyo , Ahn Junmo , Jung Hwan-Su , Yang Changsop , Ko Seok-Jae , Bu Youngmin , Park Jae-Woo , Park Kyoung Sun , Jung Hee-Jae , Lee Jun-Hwan , Lee Beom-Joon
Published: May 2019

Background
Gastro-esophageal reflux disease (GERD) is a major cause of chronic cough. GERD-induced chronic cough is difficult to diagnose because some patients do not complain of any gastrointestinal (GI) reflux symptoms. Although chronic cough due to GERD is highly prevalent, no effective treatment is currently available, especially for GERD-related cough without GI symptoms. As the herbal medicines Ojeok-san and Saengmaek-san can effectively treat GERD and cough, we aim to evaluate the efficacy and safety of a combination of these components for relieving chronic cough due to GERD.

Methods
This is a study protocol of a randomized, double-blind, placebo-controlled, single-center pilot trial. After one-week run-in period, a total of 30 patients with GERD-induced chronic cough will be randomly allocated to an intervention group (n=15) or placebo group (n=15). Participants will receive 5.76 g of Ojeok-san plus Saengmaek-san or a placebo three times per day for 6 weeks. The primary outcome measures, the frequency and severity of cough, will be recorded using a cough diary. The secondary outcome measures will include a cough visual analog scale, the Leicester Cough Questionnaire (Korean version), Gastrointestinal Symptom Rating Scale, Hull Airway Reflux (hypersensitivity) Questionnaire, Pattern Identification for Chronic Cough Questionnaire, Pattern Identification for Gastroesophageal Reflux Disease, and safety testing. Adverse events will also be reported.

Discussion
This will be the first clinical trial to explore herbal medicines for the GERD-related chronic cough, including patients without GI reflux symptoms. This study will provide useful evidence regarding the efficacy and safety of Ojeok-san plus Saengmaek-san treatment. In addition, this trial will offer scientific basis for the combination of herbal medicines. This finding will also serve as an important data for conducting a larger-scale clinical trial on GERD-induced chronic cough.

Trial registration
This trial has been registered with Clinical Research Information Service (CRIS) of South Korea (http://cris.nih.go.kr; registration number: KCT0003115). Registered August 28, 2018.
Thymosin alpha 1 in the prevention of pancreatic infection following acute necrotizing pancreatitis (TRACE trial)
Authors: Zhou Jing , Ke Lu , Mao Wenjian , Zhang Zhongheng , Li Gang , Ye Bo , Li Weiqin , Tong Zhihui , Li Jieshou
Published: May 2019

Abstract
Background: IPN and its related septic complications are the major causes of death in patients with ANP. Therefore, prevention of pancreatic infection is of great clinical value in the treatment of ANP. This study aimed to evaluate the role of Thymosin Alpha 1 in treating ANP.
Methods: Eligible patients were randomised to the treatment group(Thymosin alpha 1 group) or the control group. Occurrence of IPN will serve as the primary outcome measure of the TRACE trial. Occurrence of new-onset organ failure and persistent organ failure; CRP, HLA-DR, WBC day0, day 7 and day14; other related pancreatic complications and prognosis of the patients were also calculated.
Discussion: The TRACE trial is designed to test the effect of a new therapy focusing on the immune system in preventing secondary infection following ANP, which is a potentially lethal complication causing substantial morbidity and mortality. We also aimed to prospectively investigate the effect of immunomodulatory treatment with thymosin alpha 1 in patients with different severity of diseases with predefined subgroup analysis. The results of the TRACE trial would potentially provide a novel therapeutic option in the early management of ANP and identify the patient population who may benefit most from immunomodulation.
The trial was registered on the June 16, 2015 in the CT.gov register (NCT02473406)
Mixture Mixed Models: Biennial Growth as a Latent Variable in Coffee Bean Progenies
Authors: Vieira Júnior Indalécio Cunha , Pereira da Silva Carlos , Nuvunga Joel Jorge , Botelho César Elias , Avelar Gonçalves Flávia Maria , Balestre Márcio
Published: May 2019

Statistical analysis ofCoffea arabicaL. progeny production has been a great challenge. In this species, genotypes may present differential biennial behaviors due to different physiological responses to the environmental conditions, indicating a mixture of two subpopulations in the tested progenies. Previously proposed statistical methods are unable to handle data overdispersion and/or bimodality because they assume the same stochastic process generating different phenotypes. This study proposes a finite mixture mixed model for modeling the biennial patterns. Production data for 21 S0:1progenies, evaluated through eight harvests, were used. Individual (per harvest) and repeated measures analyses were performed using conventional mixed models and Gaussian mixture mixed models. The proposed methodology is also illustrated in a simulation study. On a real dataset, the approximated prediction error variance, CV, and residual variance were drastically reduced using mixture mixed models, resulting in a higher estimated heritability and expected gain from selection. Residual dependence across years was lower for the mixture model, but no differences were observed in genetic correlations. The posterior probability matrix captured the biennial pattern, which indicates the probability of a progeny's physiological stage. The Spearman correlation coefficient (0.87) indicates that selection based on grouped means may not be efficient. In general, the proposed model was more efficient for higher subpopulations means differences. The results suggest that for analysis ofC. arabicaprogenies exhibiting different biennial patterns, mixture mixed models are superior to traditional mixed models and to models that structure biennial effects using covariance matrices.
Interplay between Molecular Diffusion and Advection during Solute Transport in Macroporous Media
Authors: Batany Stéphane , Peyneau Pierre-Emmanuel , Lassabatère Laurent , Béchet Béatrice , Faure Paméla , Dangla Patrick
Published: May 2019

Core Ideas

BTCs in a macroporous medium cannot always be fitted by classical transport models.

Classical transport models can be faulted in a simple heterogeneous porous medium.

Molecular diffusion affects solute transport for sufficient mean residence time.

The shape of the BTCs depends on the mean residence time of the solute.

Solute transport in soils is known to differ from solute transport in homogeneous porous media. Nonequilibrium processes, like those induced by the presence of macropores, can strongly influence the breakthrough of solute in soils. Breakthrough experiments and effective models are often combined to study the physicochemical processes involved in solute transport. However, the complexity of flow pathways and the diversity of possible processes is challenging. In this work, the influence of flow rate and viscosity of the carrying liquid on nonreactive solute transport is investigated under saturated conditions in a macroporous synthetic medium. As expected, solute transport is strongly affected by physical nonequilibrium induced by the preferential flow within the macropore. Breakthrough occurs early, and the shape of the breakthrough curve is influenced both by the flow rate and the coefficient of molecular diffusion of the solute. We show that when the mean residence time of the solute in the macropore is small enough, solute transport in a macroporous column can be considered as isolated within the macropore. The increase of the residence time strongly affects the shape of the breakthrough, and, eventually, a plateau appears during the ascent of the breakthrough curve. We demonstrate experimentally that the existence of this plateau, which is not predicted by classical effective models, is related to the relative importance of molecular diffusion versus advection. Indeed, this plateau can become unobservable if the coefficient of molecular diffusion is reduced through the use of a sufficiently viscous carrying liquid.
Computación en la nube: algunas consideraciones técnico-jurídicas
Authors: Rodríguez Gladys Stella
Published: May 2019

El presente artículo analiza algunas consideraciones técnico-jurídicas del contrato denominado computación en la nube, para ello, primeramente se expone su origen, se describe su naturaleza a partir de su definición siguiendo a Joyanes, García del Poyo y la Comisión de las Naciones Unidas para el Derecho Mercantil Internacional. De igual manera, se explican las características técnicas de este servicio tecnológico, se exponen los principales proveedores que ofrecen estos modelos denegocios, se examinan las ventajas y desventajas de este tipo de acuerdo y, finalmente, se analiza el aspecto contractual, con especial referencia a la fase preliminar, que tanto cliente como proveedor debe tomar en consideración a la hora de negociar y cumplir con el complejo de acuerdos que implica la contratación en la nube. Se desarrolla una investigación no experimental de carácter descriptivo, basada en el análisis de contenidos emanados por autores y organismos especializadosen TIC, a la vez que se hace una interpretación de los documentos de la CNUDMI sobre los aspectos jurídicos.
Liderazgo pedagógico de los directivos y desempeño docente
Authors: Hidalgo Bertha Luz Rafael , Orbegoso Rivera Viky
Published: May 2019

El propósito de la investigación es determinar la influencia que existe entre el liderazgo pedagógico de los directivos y el desempeño docente de las instituciones educativas públicas de la UGEL Coronel Portillo Pucallpa. La importancia del liderazgo de los directivos como uno de los elementos que contribuyen a la calidad de la educación hace que su valoración resulte un asunto de enorme interés. La investigación tiene un enfoque cuantitativo, el método hipotético-deductivo, con un diseño de investigación no experimental correlacional de corte transversal. La población estuvo constituida por 267 docentes de la UGEL Coronel Portillo y la muestra conformada por 158 docentes. Para recoger información se aplicó un instrumento denominado cuestionario. Después de realizar los análisis de los resultados de la parte estadística, el valor de significación observada (sig:0,000) es menor al valor de la significación teórica 0,05 en las variables, se rechaza la hipótesis nula, en consecuencia, se concluye que existe influencia del liderazgo pedagógico de los directivos en el desempeño docente, además el resultado de Cox y Snell igual a 0,426 significaría que el 42,6 % El liderazgo pedagógico explica la variabilidad de la variable dependiente desempeño docente. Asimismose tiene la prueba de Nagelkerke con coeficiente 0,495, es decir, el 49.5 %, estaría explicando la variabilidad, siendo esta prueba la que presentaría una mejor dependencia entre las variables.
Methodology of complex estimation level of socio-ecological and economic development of industrial regions of Ukraine
Authors: Ilchenko Viktoriia , Goryaschenko Yuliya , Zhadko Kostyantyn , Nekhay Olexandr
Published: May 2019

The article is devoted to a comprehensive assessment and improvement of the level of regional development on the basis of determining the effectiveness of the mechanism of sustainable development of the region, developing methodical principles for the formation of regional and local strategies for ensuring sustainable development.The purpose is to substantiate the methodology and means of integral assessment to implement the principle of equalization of sustainable development of regions in the aspect of information and innovation support by means of theories of social development, systems, clustering of the economy and economic information theory.A methodological approach was proposed for assessing the level and trends of sustainable development of the region, based on the analysis of declarations, program and final documents of UN conferences on economic, social and environmental issues. The approach is based on the use of an integral index whose evaluation and analysis results can be used to solve problems and are implemented in the process of making sound management decisions. This approach made it possible to formulate, by means of factor analysis, a refined system of indicators that characterize economic, social and environmental sustainability parameters.The typical groups of industrial regions of Ukraine were identified and the level of socio-ecological and economic development was assessed. This made it possible, based on the procedures for reducing the dimension and constructing generalized indicators, to calculate the rating for each calculated integral indicator as a generalized estimate. The calculations that have been carried out make it possible to determine the trends of sustainable development of individual regions on the factors of development and to justify promising directions for effective growth and negative trends, which require the greatest attention from the state authorities and local self-government bodies.
ANÁLISE DE DESACOPLAMENTO DAS EMISSÕES DE CO2 E CRESCIMENTO ECONÔMICO
Authors: De Lima André Gomes , Rocha Diego Lilargem , Rangel João José de Assis
Published: May 2019

Este trabalho analisa o desacoplamento entre as emissões de dióxido de carbono referentes à queima de combustíveis fósseis em relação ao crescimento econômico no Brasil, na África, no mundo e nos países da Organização para a Cooperação e Desenvolvimento Econômico (OCDE) no período de 1990 a 2016. A necessidade de obter um crescimento econômico e minimizar os danos ao meio ambiente estimulou diversos pesquisadores a usarem métodos que mensuram o desenvolvimento econômico relacionado a emissões de gases de efeito estufa. Dentre eles, destacam-se o método de desacoplamento da OCDE e o método de Tapio. A aplicação do Método da OCDE demonstrou que o Brasil foi o único que não apresentou estado de desacoplamento, enquanto a África, a OCDE e o mundo apresentaram o estado de desacoplamento relativo. Esse método também demonstrou que os países da OCDE apresentaram o melhor comportamento, pois obteve o maior fator de desacoplamento. O Método de Tapio, por sua vez, confirmando os resultados obtidos pelo método da OCDE, demonstrou também que o Brasil foi o único que permaneceu, na maioria dos períodos analisados, no estado de desacoplamento negativo fraco, ou seja, apresentou um aumento de suas emissões superior à expansão econômica. O Continente africano e o mundo apresentaram um comportamento com predominância nos estados de acoplamento expansivo e desacoplamento fraco. Já a OCDE demonstrou o melhor perfil de desacoplamento entre os analisados. Esse grupo de países, nos primeiros quinze anos, atingiu o estado de desacoplamento fraco e, posteriormente, o estado de desacoplamento forte nos últimos onze anos. Ou seja, recentemente demonstrou um padrão de crescimento econômico com respectiva redução das suas emissões.
APLICAÇÃO DA TEORIA DE REDES PARA ANÁLISE LOGÍSTICA DOS HUBPORTS DA CABOTAGEM BRASILEIRA
Authors: Santos Carlos César Ribeiro , Pereira Hernane Borges de Barros , Palmeira Anderson da Silva , Cunha Marcelo do Vale
Published: May 2019

Este artigo apresenta uma aplicação da teoria de redes sob o ponto de vista da logística brasileira, especificamente o modal aquaviário e sua tipologia cabotagem. Tal análise foi permitida, a partir da disponibilidade dos dados estatísticos sobre a movimentação de cargas no Brasil advindos do Sistema Aquaviário da Agência Nacional de Transportes Aquaviários. Uma matriz para construção da rede foi estabelecida, o quê permitiu, posteriormente, a identificação das diversas métricas de redes como o grau desta, coeficiente de aglomeração e intermediação. Os portos de Santos (SP) e Suape (PE) apresentam-se com os maiores graus de entrada e saída da rede, estabelecendo-se assim como os hubports da navegação por cabotagem brasileira entre os anos de 2010 a 2015. Os resultados apresentados apontam um excesso na movimentação de cargas nos hubports, bem como uma oportunidade do ponto de vista logístico, de crescimento e investimentos em portos como Salvador(BA) e Vitória (ES) para fortalecimento da navegação marítima nacional.
Not a Painless Condition: Rheumatological and Musculoskeletal Symptoms in Type 2 Diabetes, and the Implications for Exercise Participation
Authors: Cox Emily R. , Coombes Jeff S. , Keating Shelley E. , Burton Nicola W. , Coombes Brooke K.
Published: May 2019

Objectives:

People with type 2 diabetes (T2D) are more likely to develop a range of rheumatological and musculoskeletal symptoms (RMS), and experience both chronic and widespread pain, compared with the general population. However, these symptoms are not commonly acknowledged by researchers, which hampers our understanding of the impact on this population. Since exercise is a key lifestyle management strategy for T2D and participation levels are typically low, understanding the potential impact of RMS on exercise participation is critical. The aim of this review is to summarise the literature regarding the prevalence and pathophysiology of RMS in T2D, the evidence for the benefits and risks associated with exercise on RMS, and the currently available tools for the reporting of RMS in both research studies and community settings.

Methods:

A narrative review.

Results:

There are numerous exercise trials in T2D, but few have sufficiently reported pain-related adverse events and even fewer have investigated the effects of exercise on RMS and chronic pain.

Discussion:

Recommendations for future research are provided.
Sources and Effects of Oxidative Stress in Hypertension
Authors: Pinheiro Lucas C. , Oliveira-Paula Gustavo H.
Published: May 2019

Background:

Disruption of redox signaling is a common pathophysiological mechanism
observed in several diseases. In hypertension, oxidative stress, resulted either from enhances in
Reactive Oxygen Species (ROS) production or decreases in antioxidant defenses, is associated with
increase in blood pressure, endothelial dysfunction and vascular remodeling. Although the role of
oxidative stress in the development of hypertension is well known, it is still unclear if this process is
a cause or a consequence of tissue changes in hypertension. Indeed, unbalanced ROS formation
results in several detrimental effects that contribute to hypertension, including reduction in nitric
oxide bioavailability and activation of metalloproteinases. Additionally, ROS may also directly
react with lipids, proteins and DNA, thereby contributing to tissue damage associated with hypertension.
Therefore, a deep understanding of the role of oxidative stress in hypertension is essential
to comprehend its pathophysiology and to identify new therapeutic targets.

Conclusion:

This mini-review discusses the main enzymatic sources of oxidants and the major
antioxidant defenses in the vasculature, followed by the effects of oxidative stress in hypertension,
highlighting endothelial dysfunction, vascular remodeling and tissue damage.
Tektekan calonarang at puri anyar kerambitan
Authors: Sariada I  Ketut , Ginaya Gede
Published: May 2019

This study aims at presenting the comprehensive insight on the commodification of Tektekan Calonarang in Puri Anyar Kerambitan which uses sacred barong and rangda for tourism. The data was collected through observation, in depth-interview, and literature study. The collected data then analyzed using the descriptive qualitative method. The theories of deconstruction, social practice, aesthetic, and power/knowledge are used to undertake this study. The results of the study reveal that positive and negative influences of tourism occur in the context of traditional performing arts. The emergence of creativity is very evident in the rapid development of various types of performing arts in Bali including the increasing number of art activists, but at the same time several sacred dances including ritual procession elements, such as Tektekan Calonarang in Puri Anyar Kerambitan have become in between sacred or profane because they have been shown to tourists.
NAMING DISPLACED PEOPLE: NEW PATTERNS IN MEDIA DISCOURSE? A DISCOURSE ANALYSIS OF LE MONDE AND LE FIGARO
Authors: Calabrese Laura , Mistiaen Valériane
Published: May 2019

The migrant crisis has received huge media coverage and has been the subject of many social controversies, among which the one sparked by Al Jazeera regarding the words migrant and refugee during the summer 2015. !is study addresses thequestion of whether the lexical debate that followed had a permanent impact in journalistic writing patterns, by analysing media typifications of displaced people. Using a mixed methodology of corpus linguistics and discourse analysis, we analyseda corpus of 376,217 words from the two main French broadsheet newspapers, Le Monde and Le Figaro, in order to observe if the lexical debate influenced the choice of words of the journalists. !e results of the study show that if some changesare visible a$er the debate (a higher frequency of refugee as well as an accurate usage of this legal term), the latter did not prevent journalists from using the word migrant (in spite of the negative connotations Al Jazeera decried). !e study concludeswith some hypotheses about the future of those terms, as they will continue expanding their meaning and their referent according to historical events.
Literacy of Croatian vocational school students in school assignments and texts written in new media in leisure time
Authors: Filipan-Žignić Blaženka , Legac Vladimir , Sobo Katica
Published: May 2019

Communication by means of new media inevitably leads to changes in language that are reflected in a new type of discourse. The main features of this discourse are the use of abbreviations, emoticons, dialecticism, anglicisms, neologisms, vulgarisms, and profanities. This way of writing, however, is often seen as writing with a lot of errors, which then have a negative influence on literacy in general and, particularly, on the literacy of young people. Therefore, during 2016, the authors of this article conducted a research study of the real literacy of young people analyzing school assignments written by students in their final years of vocational schools and their communication in new media. The 2016 research study was a follow-up study to the research study that had been carried out in 2015 with grammar school students. This new research study compared vocational school students with grammar school students in Croatia.
Sugestões de Leitura V.2, N.2 2016
Authors: Dobbins Chennyfer
Published: May 2019

Segurança do Paciente - Infecção Relacionada À Assistência E Outros Eventos Adversos Não Infecciosos.Editora: MedbookAno: 2016ISBN: 9788583690207.Autores: Renato Camargos Couto, Tania Moreira Grillo Pedrosa e Débora Borges do Amaral.Nos últimos 20 anos a cultura assistencial e o requisito legal, por intermédio da Agência Nacional de Saúde Suplementar e da Agência Nacional de Vigilância Sanitária, vêm incorporando a Gestão de risco como atividade central da assistência, criando um ambiente adequado à implementação das mudanças necessárias em nossas organizações assistenciais. A ciência vem mostrando que há um caminho para que sejam evitadas dezenas de milhares de óbitos e sequelas transitórias e definitivas e para o controle do desperdício de milhões de reais essenciais à sustentabilidade do SUS e da Saúde suplementar brasileira. Com certeza a obra Segurança do Paciente – Infecção Relacionada à Assistência e Outros Eventos Adversos Não Infecciosos – Prevenção, Controle e Tratamento proporcionará ao leitor acesso ao conhecimento disponibilizado dentro da melhor evidência científica, em um formato adaptado à realidade brasileira, tornando-se um dos pilares fundamentais para a mudança.
Editorial
Authors: Hargreaves Luiz Henrique Horta
Published: May 2019

O Instituto Brasileiro de Capacitação, Desenvolvimento e Gestão Profissional é uma organização destinada ao ensino, pesquisa, desenvolvimento e projetos destinados à saúde e administração.Dando continuidade ao sucesso no empreendimento de seu International Journal of Health Management Review, lança o terceiro ano. Esse esforço é fruto de uma criteriosa avaliação de trabalhos acadêmicos que possuem afinidade com a proposta de melhorar o sistema de saúde brasileiro.
Qualidade microbiológica do consumo de pescado cru na culinária japonesa: síntese de evidências
Authors: Olivetto Michely Calixto , Ferraz Renato Ribeiro Nogueira
Published: May 2019

Introdução: Nas últimas décadas com a globalização, a alimentação tem sido motivo de preocupação em todos os países, ficando evidente os problemas relativos à sua qualidade para consumo e o impacto socioeconômico que pode vir a gerar. Apesar das várias qualidades do peixe, muito consumido na culinária japonesa, é considerado de alto risco por ser um alimento perecíveis e de fácil oxidação da gordura. Podendo assim, veicular microrganismos que fazem parte da microbiota natural do pescado, da água ou originária da má manipulação. Objetivo: Revisar a literatura buscando evidenciar os aspectos sobre a qualidade microbiológica encontrada no pescado cru dos alimentos da culinária japonesa (sushi e sashimi). Método: Trata-se de uma pesquisa exploratória baseada em uma revisão da literatura com síntese de evidências, por meio da ferramenta de procura Publish or Perish, em que foram selecionados os artigos de maior relevância. Conclusão: A literatura demonstra que o pescado na sua forma crua pode se tornar um veículo de microrganismos como: E. coli, Salmonella spp., S. aureus, vibrio spp. e principalmente a coliformes termotolerantes. Deste modo, é fundamental que os manipuladores tenham consciência da necessidade das boas práticas em todos os processos da cadeia de produção, principalmente quando o alimento não passa pela etapa de cocção, aonde ocorre a redução dessa carga microbiana, que pode multiplicar quando exposto a temperatura ambiente por muito tempo.
Sugestões de Leitura e Agenda de Eventos
Authors: IJHM IJHM
Published: May 2019

Sugestões de Leitura e Agenda de Eventos.
Avaliação das boas práticas de fabricação em panificadoras por meio da aplicabilidade de check-list no município de Campinas - SP
Authors: Machado Gabriela Galante
Published: May 2019

Nos últimos anos, observou-se a expansão de diversos setores na área de alimentação, sendo as panificadoras um dos que mais cresceram em todo o mundo. Portanto, devido a este crescimento tão promissor, surgiram às preocupações com a qualidade higiênicosanitária das padarias. Desta forma, o objetivo principal deste estudo foi avaliar as boas práticas de fabricação em duas panificadoras localizadas no Município de Campinas-SP. O instrumento utilizado para coleta dos dados foi uma lista de verificação (check-list) disponibilizada na resolução - RDC n° 275/2002, que conta com diversificados itens de verificação, divididos em cinco módulos: I- Edificações e Instalações; II – Equipamentos móveis e Utensílios; III – Manipuladores; IV – Produção e Transporte do Alimento e V– Documentação. Após a aplicação da lista de verificação, cinco perguntas elaboradas e padronizadas para ambos os estabelecimentos, foram realizadas aos proprietários, a fim de elucidar as inconformidades encontradas. Deste modo, os resultados obtidos apontaram diversas não conformidades nos estabelecimentos avaliados, sendo a padaria B a de pior atendimento as boas práticas de fabricação, tanto ao ser avaliada e classificada de forma geral, como ao ser avaliada individualmente em seus módulos, quando comparada a padaria A, embora nenhuma das panificadoras tenham sido classificadas em Grupo 1 – BOM, considerando o de melhor atendimento as boas práticas de fabricação. Conclui-se então que ambos os locais não apresentam adequação as boas práticas e porisso, colocam em risco a saúde de seus consumidores.
Cascade Monitoring in Multidisciplinary Adolescent HIV Care Settings: Protocol for Utilizing Electronic Health Records (Preprint)
Authors: Pennar Amy L , Dark Tyra , Simpson Kit N , Gurung Sitaji , Cain Demetria , Fan Carolyn , Parsons Jeffrey T , Naar Sylvie
Published: May 2019

BACKGROUND

Past research shows that youth living with HIV (YLH) are not as engaged in the HIV treatment cascade as other HIV-positive populations. To achieve the health benefits of rapid and widespread testing and advanced pharmacologic treatment, YLH must be fully engaged in every stage of the treatment cascade. Cascade monitoring provides an opportunity to assess the youth care cascade, including engagement in care and when youth commonly drop out of care, across 10 clinical sites in the United States. Collecting electronic health record (EHR) data for prevention and care across participant recruitment venues within the Adolescent Medicine Trials Network (ATN) allows for monitoring of the prevention and care cascades within the ATN, for comparing the ATN population to large-scale surveillance, for future integration of technology-based interventions into EHRs, and for informing ATN strategic planning.

OBJECTIVE

The aim of this protocol study is to examine the trends in treatment cascade, including whether patients are receiving antiretroviral therapy, adhering to regimens, attending care appointments, and maintaining suppressed viral loads, to guide new protocol development and to facilitate community engagement. This protocol is part of the ATN Scale It Up (SIU) program described in this issue.

METHODS

Deidentified EHR data of YLH, aged 15 to 24 years, will be collected annually (2017 to 2022) from 10 ATN clinical sites, resulting in patient data from 2016 to 2021. These data will be transferred and stored using Dropbox Business, a Health Insurance Portability and Accountability Act–compliant site and then analyzed by the SIU analytic core.

RESULTS

This study was launched in December 2017 in 10 clinical sites, with 2016’s EHR data due on January 31, 2017. All 10 sites electronically uploaded their EHR data. The mandatory variables requested to monitor cascade of care include date of visit, age, gender, height, weight, race, ethnicity, viral load, and International Classification of Diseases codes for other diagnosis. In total, 70% of the sites provided data for all mandatory variables. The remaining mandatory variables were manually extracted.

CONCLUSIONS

This study will provide a platform to determine how YLH across the nation progress through or drop out of the HIV treatment cascade. It will also provide a foundation for assessing impact of SIU projects on treatment cascade outcomes.
A Scale to Assess the Methodological Quality of Studies Assessing Usability of Electronic Health Products and Services: Delphi Study Followed by Validity and Reliability Testing (Preprint)
Authors: Silva Anabela G , Simões Patrícia , Santos Rita , Queirós Alexandra , Rocha Nelson P , Rodrigues Mário
Published: May 2019

BACKGROUND

The usability of electronic health (eHealth) and mobile health apps is of paramount importance as it impacts the quality of care. Methodological quality assessment is a common practice in the field of health for different designs and types of studies. However, we were unable to find a scale to assess the methodological quality of studies on the usability of eHealth products or services.

OBJECTIVE

This study aimed to develop a scale to assess the methodological quality of studies assessing usability of mobile apps and to perform a preliminary analysis of of the scale’s feasibility, reliability, and construct validity on studies assessing usability of mobile apps, measuring aspects of physical activity.

METHODS

A 3-round Delphi panel was used to generate a pool of items considered important when assessing the quality of studies on the usability of mobile apps. These items were used to write the scale and the guide to assist its use. The scale was then used to assess the quality of studies on usability of mobile apps for physical activity, and it assessed in terms of feasibility, interrater reliability, and construct validity.

RESULTS

A total of 25 experts participated in the Delphi panel, and a 15-item scale was developed. This scale was shown to be feasible (time of application mean 13.10 [SD 2.59] min), reliable (intraclass correlation coefficient=0.81; 95% CI 0.55-0.93), and able to discriminate between low- and high-quality studies (high quality: mean 9.22 [SD 0.36]; low quality: mean 6.86 [SD 0.80]; P=.01).

CONCLUSIONS

The scale that was developed can be used both to assess the methodological quality of usability studies and to inform its planning.
A Web-Based Intervention for Social Media Addiction Disorder Management in Higher Education: Quantitative Survey Study (Preprint)
Authors: Dogan Huseyin , Norman Helmi , Alrobai Amen , Jiang Nan , Nordin Norazah , Adnan Anita
Published: May 2019

BACKGROUND

Social media addiction disorder has recently become a major concern and has been reported to have negative impacts on postgraduate studies, particularly addiction to Facebook. Although previous studies have investigated the effects of Facebook addiction disorder in learning settings, there still has been a lack of studies investigating the relationship between online intervention features for Facebook addiction focusing on postgraduate studies.

OBJECTIVE

In an attempt to understand this relationship, this study aimed to carry out an investigation on online intervention features for effective management of Facebook addiction in higher education.

METHODS

This study was conducted quantitatively using surveys and partial least square-structural equational modeling. The study involved 200 postgraduates in a Facebook support group for postgraduates. The Bergen Facebook Addiction test was used to assess postgraduates’ Facebook addiction level, whereas online intervention features were used to assess postgraduates’ perceptions of online intervention features for Facebook addiction, which are as follows: (1) self-monitoring features, (2) manual control features, (3) notification features, (4) automatic control features, and (5) reward features.

RESULTS

The study discovered six Facebook addiction factors (relapse, conflict, salience, tolerance, withdrawal, and mood modification) and five intervention features (notification, auto-control, reward, manual control, and self-monitoring) that could be used in the management of Facebook addiction in postgraduate education. The study also revealed that relapse is the most important factor and mood modification is the least important factor. Furthermore, findings indicated that notification was the most important intervention feature, whereas self-monitoring was the least important feature.

CONCLUSIONS

The study’s findings (addiction factors and intervention features) could assist future developers and educators in the development of online intervention tools for Facebook addiction management in postgraduate education.
Will Central and Eastern European Countries Dismantle the European Union?—Contrasting European Developments to Current Trends in the US
Authors: Major Iván
Published: May 2019

This paper analyzes the historical background of the current developments in Central Eastern Europe, in other parts of Eastern Europe and in previously member countries of the former Soviet Union. The author concludes that the political and economic transformation of these countries to a solid democracy and well-functioning market economy have not been successful for most of them yet, and this may have serious consequences on the European Union, too.The paper contrasts these trends with what we can observe in the United States now. The author turns to the “hard facts” next, when he discusses the different factors of human and economic development and the issue of migration in the Central and East European post-socialist countries and in a selected group of advanced countries.