bluuebunny/crossref_metadata_2025 huggingface dataset:
UTILISING CRISPR/Cas 9 FOR GENE EDITING TO ADDRESS HEREDITARY MOVEMENT DISORDER
Authors: Upadhyay Isha , Singh Ankita
Published: June 2024

Gene therapy offers a promising approach for addressing hereditary movement disorders like Huntington's disease, Ataxia, Dystonia and Parkinson's disease. A method known as genome editing, involves the modification of DNA by inserting, deleting, or replacing specific sequences, has gained much attention in the past few years. A prominent tool in this field is the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein 9 (CRISPR/Cas9) system. Cas9 is obtained from the bacteria, Campylobacter jejuni. CRISPR-Cas was originally a part of the Streptococcus pyogenes adaptive immune system, but CRISPR/Cas9 now serves as a valuable tool for genome editing, causing breaks in the DNA strands under the guidance of RNA (gRNA). In contrast to alternative genome editing techniques like zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs), CRISPR/Cas9 stands out for its potential clinical applicability due to its convenient in vivo delivery. It is highly specific and cuts only a limited number of sites in the genome. This chapter explores and assesses the viability of CRISPR/Cas9 in the preclinical research and its potential use in gene therapy for hereditary movement disorders.
IMPLEMENTATION OF EDGE COMPUTING PARADIGM IN IOT TECHNOLOGY
Authors: Chinchawade Dr. Amit Jaykumar , O.S. Lamba Dr.
Published: June 2024

The rapid evolution of net of things (IoT) era has ushered in a new technology of interconnected devices, generating huge volumes of records. traditional cloud-primarily based architectures face demanding situations in coping with the increasing demands for low-latency, actual-time processing and decreased bandwidth utilization. In response to those challenges, this paper proposes the implementation of part Computing Paradigm in IoT technology. part computing is a decentralized computing model that brings computation and statistics garage towards the supply of information generation, thereby lowering latency and enhancing the overall gadget overall performance. within the context of IoT, deploying aspect computing on the network periphery lets in for actual-time facts processing, analysis, and selection-making. This paper explores the combination of part computing into the IoT atmosphere and investigates its ability benefits and demanding situations. This paper presents a comprehensive exploration of the implementation of the edge computing paradigm in IoT technology. By leveraging the proximity of computation to data sources, this approach addresses key challenges in latency, security, and energy efficiency, paving the way for a more responsive and scalable IoT ecosystem. The findings of this research contribute valuable insights to the ongoing discourse on advancing IoT technologies through innovative computing paradigms.
ULTRASONIC RADAR SYSTEM FOR OBJECT DETECTION
Authors: Praveen Kumar Mr. R , M.Divya Miss.
Published: June 2024

In a variety of settings, including military installations and commercial use, the use of RADAR SYSTEM, which uses electromagnetic waves for the detection of different physical components such as distance, speed, position, range, direction, size, etc., which may be either fixed or in motion, is made possible. Radar technology has substantially evolved, particularly in navigation. We looked at the status of navigational technology in this study and proposed an Arduino-based radar system. The system consists of a simple ultrasonic sensor installed on a servo motor that rotates at a predetermined angle and speed. Both the servo motor and this ultrasonic sensor are wired to the digital input and output pins of the Arduino. The objective of this paper is to construct an ultrasonic transceiver, which is essentially a form of radar system that can gauge the precise distance and angle of stationary objects placed around it using the speed of ultrasonic waves in open space. An Arduino microcontroller was used to transmit and receive 40 KHz ultrasonic waves in order to meet the needs of flexible usage. Sound reflection is controlled by the time delay between the sent and received waves. We construct a basic radar employing an ultrasonic sensor; this radar measures non-contact distances between 3 and 40 cm and angles between 15 and 180 degrees.A tiny servo motor is used to regulate the sensor's movement. The goal of this study is to build an ultrasonic radar system using an Arduino interface and ultrasonic waves. To make advantage of these frequency range waves, we can employ the ultrasonic sensor HC-SR04. When an Arduino, a control and sensing device, is linked to this sensor. The Arduino will allow companies to produce a lot more distinctive products without having to spend a lot of money on numerous rigid circuit boards. This radar system can be used as proximity detectors and range metres in industries. Hardware for the ultrasonic sensor is linked to an Arduino. This measurement technique is a rapid and reliable way to find the objects. The distance between a barrier and the sensor is measured using ultrasonic technology.
COMMUNICATING GENDER IN AGRICULTURE DEVELOPMENT PROJECTS
Authors: Kabita Kumari Dash Dr. , Chitrita Prusty Dr.
Published: June 2024

A gender aware project brings transformation in the society and recognizes the contribution of both men and women in the development process. Empowerment indicates a situation whereby both men and women take control of their life, gain skill, build up confidence and march together towards a self-reliant society. Hence, to make the agriculture development projects, gender sensitive, a proper communication strategy on the understanding of the different roles and responsibilities, needs and concerns of both, needs to be developed. All the development projects should aim for gender integration in its project areas for better project output. Women’s involvement in agriculture and allied activities along with socio-political participation catalyses the empowerment process. Hence, a concerted and coordinated approach is necessary to bring a change in the society related to gender. Women’s equality and empowerment should be taken on board as an important aspect of agriculture management. Adoption of appropriate gender friendly technologies, capacity building training, awareness along with proper communication strategy would certainly pave a new path towards agriculture development.
A COMPREHENSIVE REVIEW ON PROBIOTICS AND ITS SIGNIFICANCE
Authors: Gupta Sakshi , Singh Shanker Suwan , Chaudahry Raveena
Published: June 2024

Probiotics contain live bacteria and yeast that when consumed in adequate amount do wonders to human health. The most popular super supplements available in the market today are Probiotics. Bacteria’s are usually considered as dangerous or harmful, but the fact is human body contains both types of bacteria i.e., good and bad. Hence, Probiotics are good bacteria which are required by our body. In this review, an overview of probiotics, gut health benefits, their role in immune system and disease prevention. Furthermore, current trends in the development of probiotic products also discussed. Overall, this review aims at better understanding of probiotics and their significance as emerging functional foods.
FOOD SUPPLEMENTS USED IN FUNCTIONAL DAIRY PRODUCTS
Authors: Albay Zehra , Simsek Bedia
Published: June 2024

Functional dairy products include enhanced dairy products, low-calorie milk products, low-sodium dairy products, probiotic and/or prebiotic milk, and phenylalanine amino acids. Products that include probiotics make up the most significant group of functional dairy products. Combinations of probiotics and prebiotics have been shown to have a greater beneficial impact on human health in research on symbiotic relationships. Functional dairy products may be produced by including Omega-3 polyunsaturated fatty acids, minerals, vitamins, soluble fiber, and antioxidants. Furthermore, functional dairy products with a lower calorie value, sodium, lactose, or phenylalanine amino acids are manufactured for feeding people with particular disorders. Functional dairy products are clearly important in terms of health and nutrition. The most significant aspect of incorporating these products into our everyday diet is the advancement of consumer consciousness and associated scientific investigations.
MARINE-DERIVED BIOACTIVE PEPTIDES AND THEIR HEALTH-PROMOTING PROPERTIES
Authors: Ozgen Sara Betul , Ozer Emir Ayse
Published: June 2024

Bioactive peptides are chains of acids that have the ability to produce specific effects, on the human body. These peptides can be obtained from sources, such, as animal, plant and microbial proteins. Among these marine derived bioactive peptides possess a significant place in literature. In years a lot of research has been conducted on producing, purifying and characterizing peptides because of their potential to promote good health. This chapter aims to explore the methods used in generating marine derived peptides and the techniques employed for their purification and characterization. Moreover it will delve into the range of health benefits associated with consuming bioactive peptides.
MULTILAYER FARMING: A SOLUTION OF MANY PROBLEMS
Authors: Desai J. S. , Patel D. K. , Desai C. K. , Suthar N. K.
Published: June 2024

Human want is indefinite that never satisfy. For that reasons they burned anything for their need. We can see it from our periphery that industrialization is occur more and more day by day. Understanding that human population is increasing rapidly from past few decade and urbanization is possible way to give stay for that population but not in cost of agriculture land. Farmers often try new ideas in their fields based on deep knowledge of their local environment and develop many ecologically and environmentally sound local technologies/ farming practices by innovations and adaptations. One of these practices is known as Multilayer Farming. It is based on space and time annidiation. Generally the practices of planting two or more crop on same piece of land is more common in tropical region where more rainfall, high temperature and longer growing season are more favourable for continual crop production. Multilayer farming is a method of simultaneously cultivating crops of various heights on the same plot of land. Other names for it include multi-tier cropping and multi-storied cropping. This kind of cropping is typically used to maximise the use of solar energy even with dense plant populations. Using the resources at their elimination, the farmers can use the same plot of land to produce a good crop and increase their revenues. Additionally, it addresses the issue of feeding a growing population with limited cultivable land. The primary goal of this kind of farming is to make better use of vertical space. The tallest components in this system have foliage that requires intense light and high evaporative demand, while the shorter components have foliage that requires shade and high humidity. The other goals of multilayer farming are maximising productivity per unit of land, harvesting crops on a regular basis throughout the year, and water conservation.
PROBIOTIC FOODS – THY MEDICINE
Authors: G Sai Bramari. , L. Anitha Dr.
Published: June 2024

The metabolic energy for body is obtained from food. The food with right proportions and composition of ingredients can act as a good medicine. The foods with certain beneficiary organisms like Lactic acid bacteria enrich the food with various health benefits improves overall gut health. These fermented foods with beneficiary microorganisms are called probiotic foods. The probiotic organisms can be considered as altruistic and in favor of human health aspects. "Probiotic foods are the secret to a thriving gut and flourishing us, supporting our immune system, digestion, and overall well-being with each delicious bite." Let us explore more about probiotic foods in this chapter.
NANO BIOACTIVE COMPOUNDS IN FOOD DELIVERY SYSTEM
Authors: K V Sucharitha Dr. , Kalavathi M.
Published: June 2024

Bioactive compounds have immense health benefits and disease preventive characteristics due to the few limitations in delivering them into the targeted sites in the human body it is not effective as desired. In the past few years, there has been a growing compulsion with preparing effective food grade oral nano-delivery systems to improve the bioavailability of bioactive compounds such as bioactive lipids, bioactive proteins and bioactive carbohydrates. Encapsulation of bioactive compounds using Nano oral delivery systems like nano emulsions, nano liposomes etc has capability to enhance bioavailability of bioactive compounds. It can reach to the targeted site of the human body and it can resist the high acidity and enzymatic activity in the stomach. This book chapter focused on the types of bioactive compounds and their limitation in controlled delivering in the human body and how can it be enhanced by using nano delivery systems.
SOIL EVALUATION AND CONSERVATION IN IoT
Authors: Lakshmi I.
Published: June 2024

The present IoT (Internet of Things) initiative aims to streamline agricultural processes for farmers by implementing an efficient monitoring system for their fields. This system provides relevant information pertaining to the specific crop and corresponding traits that are most appropriate for growth and productivity. The present manuscript provides guidance to the user regarding the selection of plants for cultivation, contingent upon the characteristics of the soil. The existing framework for assessing soil for agricultural purposes is fraught with several noteworthy inadequacies. The utilization of cover crops for soil moisture management has been noted to have a significant impact on the proliferation of pests, insects, and diseases. Farmers who possess a limited level of expertise may be challenged to effectively navigate the intricacies of agricultural practices, potentially leading to the emergence of allelopathic impacts.
CONVERGING BLOCKCHAIN, AI, AND IOT: PIONEERING INDUSTRY 4.0 TRANSFORMATION AND PERFORMANCE ENHANCEMENT
Authors: Hemavathi Ms.
Published: June 2024

In an era defined by data-driven transformations and technological integration, the convergence of blockchain and artificial intelligence (AI) emerges as a catalyst for unprecedented advancements. These groundbreaking technologies, individually impactful, are now synergistically explored to reshape industries within the horizon of Industry 4.0. Blockchain, initially conceptualized for cryptocurrencies, has evolved into a decentralized ledger fostering transparency and trust. Concurrently, AI empowers intelligent decision-making through machine learning and data analysis. This paper delves into their integration and synergy, unveiling their potential to revolutionize industries. The ensuing sections elucidate specific use cases, including supply chain management and decentralized AI marketplaces, augmented by the Internet of Things (IoT) and fortified with enhanced security measures.
VITILIGO AN IDIOPATHIC DISORDER
Authors: Sharma Anupama , Chandra Sharma Girish
Published: June 2024

Vitiligo, a hypomelanotic disorder characterized by distinct patches of hypopigmentation. It delves into the clinical manifestations, prevalence, psychiatric morbidity, and social impacts of vitiligo. Furthermore, it explores the condition's pathogenesis, biochemical basis, and the role of key enzymes like tyrosinase in melanin production. The review assesses the involvement of melanocytes and keratinocytes in melanin synthesis, emphasizing the significance of β 2 adrenergic receptors in elevating melanogenesis. It highlights the potential impact of beta-blockers on vitiligo and discusses the role of antimelanocyte antibodies in melanocyte destruction. The document examines alternative agents for regulating melanogenesis, such as arbutin, kojic acid, aloesin, and azelaic acid, along with their mechanisms of action. It also discusses the biochemical and adverse effects of hydroquinone, a prominent melanogenesis inhibitor. Moreover, the review explores immunomodulation, therapeutic approaches, measurement techniques for vitiligo area, and various treatment modalities encompassing topical treatments, systemic therapies, surgical interventions, and their respective successes and side effects. The abstract concludes by emphasizing the autoimmune hypothesis as the primary etiology of vitiligo, highlighting the significance of ongoing research and clinical trials in unveiling innovative therapeutic pathways for pigmentation modulation."
QUALITY ASSESSMENT OF DIALYSIS WATER
Authors: Shaheen Sameera , Mohammadi Nazia , Ahmed Summaya , Begum Sophiya
Published: June 2024

Dialysis water, also known as dialysate, is a special type of water used in the dialysis process. Dialysis is a medical procedure that helps remove waste products and excess fluid from the blood when the kidneys are unable to do the job adequately. Dialysis water is thoroughly purified and treated to ensure its safety and suitability for the dialysis process. It is produced by water purification systems that remove impurities including minerals, bacteria, viruses and other contaminants. The purification process usually involves several steps such as filtration, reverse osmosis and deionization .Two water samples are collected directly from RO plant sources as in WC.R outlet storage tank into one litre Bisleri package water bottle and + clarifications .The method used in lab is Desired testing tailor test, .and code package (TTP).The physical attributes and the mineral composition water are under permissible unit as per WHO guidelines.According to Indian government haemodialysis guidelines, acceptable limits of bacterial contamination of treated water and dialysis were considered below 200 CFU/ml and below 2000 CFU/ml, respectively.
EXPLORING THE ROLE OF HOMOEOPATHY IN THE MANAGEMENT OF ACUTE LOWER URINARY TRACT INFECTION IN PAEDIATRIC AGE GROUP
Authors: Amolakchand Jain Dr. Sushil
Published: June 2024

Urinary tract infection are caused by a range of pathogen and most commonly caused by E coli, klebseila. It is the most common cause of infection in paediatric age group. Most lower urinary tract infection (confined to bladder and urethra) in children aged less than 5 years present only as fever without localization so it's generally at times missed out. A prospective Experimental, single blind, randomized study was conducted in children age 3 years to 18 years. Sample size was 30 cases. Cases selection was based on clinically symptomatic children as well as urine analysis reports and inclusion criteria. The purpose of this study was to evaluate the role of Homeopathy in treatment of acute lower urinary tract infection. Data collection was done in a systematic manner with a case data record sheet and questionnaire. The Outcome was evaluated based on clinical symptomatic improvement (general and particular) as well as on urine routine analysis. The study proved that Homeopathic mode of treatment is effective in treating lower urinary tract infection in paediatric age group.
PALLIATIVE CARE IN CANCER: A REVIEW OF PRESENT, PROGRESS AND FUTURE TRENDS
Authors: Shatakshi Mishra , Rashmi Gupta
Published: June 2024

Palliative care and hospices developed promptly science the late 1960s and in India 1980s. It is also known as end of life care (EoLC) which is specialize Palliative care improves quality of life and gives care with satisfaction especially for advanced cancer patient and it originated to seeing death of people from acute to chronic conditions of cancer and other diseases. It gives emphasis on improving quality of life of patients. Palliative care is designed for terminally ill person and for their families. Palliative care is given in cancer, dementia, heart failure, chronic obstructive pulmonary disease, and Parkinson’s disease etc whereas in some countries palliative care given especially given in cancer such as United Kingdom through hospices and support teams. It can be said that mainly it is related to oncology. Goal of palliative care is to prevent or treat symptoms and side effects of disease of individual soon as possible on the basis of physical, social, and spiritual problems. Any person can receive it without hesitate about age and stage of disease. It can be received in hospitals, a long term care facility centre, an outpatient clinic, or at home under supervision of certified health care provider. Cancer patient receive many treatment such as chemo therapy, radio therapy, surgery, medicines etc, but palliative care provide people and their families more comfortable.
ETHNOMEDICINE: A CASE STUDY NATIVE PLANT SPECIES USED FOR TREATMENT OF MALARIA AND TYPHOID FEVER EDO STATE NIGERIA
Authors: P.M Sarada , E. F. Okosodo
Published: June 2024

This chapter examined the botanical survey of native plant species used for the treatment of malaria and Typhoid fever in two agro ecological zones in Edo state. The primary goal of the botanical survey is to identify and document native plant species that are traditionally used by local communities for the treatment of malaria and Typhoid fever. This information can be valuable in understanding the local knowledge and practices related to herbal medicine. Direct observation was used for field survey in collecting medicinal plant species. In the 20 villages around the state two well-known and heavily frequented traditional healing houses from each village were visited. The plants were recognized using their common names, and their scientific names were discovered and recorded. With the help of a book on the trees of Nigeria, herbs were identified and their uses were noted as the inventory of accessible herbs was kept. The result shown that all the parts of the plant species are utilized, leaves, barks, flowers, roots, seeds, fruits. In all leaves was widely used at of the one hundred and ten (110) plants recorded.
ADVANCED DIAGNOSTIC PATHOLOGY FOR WOMEN’S HEALTH: FUTURISTIC TRENDS SHAPING PERSONALIZED CARE AND EARLY DETECTION
Authors: Chakrabarty Susmita , Priyadarsini Mishra Monali
Published: June 2024

This chapter presents an overview of advanced diagnostic pathology trends in women's health, focusing on their role in enabling personalized care and early detection of diseases. As the field of medicine continues to evolve rapidly, novel technologies and innovative approaches are transforming the landscape of diagnostic pathology for women's health. The integration of artificial intelligence, genomics, and molecular diagnostics has revolutionized diagnostic capabilities, offering unprecedented opportunities for tailored and targeted patient care. This chapter explores the potential of these futuristic trends in improving the accuracy, efficiency, and accessibility of women's health diagnostics. AI-driven algorithms have demonstrated remarkable accuracy in identifying patterns and biomarkers, enabling early detection and precise diagnosis of gynaecological conditions such as cervical and ovarian cancers. The application of genomics in diagnostic pathology has opened new avenues for understanding genetic predispositions and personalized treatment plans, thereby enhancing patient outcomes.
PHOTO-RECHARGEABLE SUPERCAPACITOR: MODES OF INTEGRATION, APPLICATIONS, CHALLENGES, AND FUTURE PROSPECTS
Authors: Beniwal Shivang , Patel Akash , Singh Meetesh
Published: June 2024

Due to the increasing energy needs and exacerbating levels of greenhouse gases and environmental pollution, developing clean and sustainable energy sources has drawn much attention in recent years. These renewable energy sources need suitable energy storage systems because of their sporadic nature. Among the various energy storage technologies, Photo-rechargeable-supercapacitors (P-SCs), a type of electrochemical energy storage device, have drawn attention from around the world due to their use in portable electronics, electric vehicles, power supplies, and a variety of other applications. However, the seamless integration of solar cells and supercapacitors presents challenges such as bulkiness, external connections, and manufacturing costs, thus limiting practicality. To address these issues and enhance system viability, the concept of self-rechargeable supercapacitors has gained significant traction. This innovative fusion aligns seamlessly with broader goals of sustainable energy transformation, offering a pragmatic and practical response to the energy needs of our interconnected world. This chapter emphasizes the photo-rechargeable supercapacitor and its Modes of integration, applications, challenges, and future prospects.
MARINE-DERIVED NATURAL PRODUCTS: A NOVEL SOURCE OF POTENTIAL ANTICANCER DRUGS IN THE OCEAN
Authors: Kharad Sharayu , Sole Shital , Thorat Renuka , Pawar Anil , Pandhare Ramdas , Deshmukh Vinayak , Mohite Popat
Published: June 2024

Cancer continues to rank among the deadliest diseases in the world. Living organisms have been studied for potential cancer treatments due to the need for new drugs. By using molecular modelling and chemical synthesis, it has been discovered that the marine environment is a rich source of chemicals with unique chemical properties that can be applied to improve the specificity, effectiveness of cutting-edge medications. Many unique bioactive metabolites with various chemical structures have been found in marine populations. This overview includes information on marine plants, bacteria, algae, sponges, fungi, soft coral, and actinomycetes, with an emphasis on the last two. Studies on marine natural products' capacity to fight cancer as well as their effectiveness in suppressing tumors, compound-induced apoptosis, and cytotoxicity were initially studied in connection to in vitro and in vivo research. It is also covered how the biological effects are supported by molecular processes. In this book chapter, we highlighted the variety of marine species, as well as the inventiveness of chemical structures and chemical property space. The usage of components obtained from marine sources, treatment methods, and discussions of their potential future uses as anticancer drugs are also included.
RECENT ADVANCEMENTS IN CARBON NANOPARTICLES AND ITS APPLICATION AS NANO FERTILIZER FOR ENHANCEMENT OF GROWTH TO VARIOUS CROPS IN THE FIELD OF AGRICULTURE
Authors: Rakesh Mr. , Babitha Mrs.
Published: June 2024

Agriculture is the key feature for sustained growth and development of any country. Food is the essential part of all living organisms. So, evolution in food industry is very important for developing country like India. With increase in population which may reach around 10 billion in near future results in scarcity of food. Thus, increase in production of various required raw materials which can be obtained from farming in limited time remains always hot topic. Hence, Fertilizers play a vital role to increase the yield of various essential crops in Agriculture. Particularly, nano fertilizer helps in reaching the above goal at faster rate. Organic nano fertilizers like carbon nano fertilizers have been found greater advantage compared to other chemical fertilizers in terms of increase in stem height, life span, yield of product, quality of soil, hybrid substances and many other aspects constrained to the growth of the plant
ADVANCEMENT IN MEDICAL IMAGING: NANOTECHNOLOGY
Authors: Sharma Rohit , Siddhartha Mr. , Ghazi Mr. , Sweety Pal Ms.
Published: June 2024

The integration of nanomaterials has significantly enhanced the sensitivity, specificity, and versatility of imaging modalities. In this chapter we explored the utilization of nanoscale contrast agents, such as quantum dots and magnetic nanoparticles, to improve the visualization of tissues and targets. Targeted imaging, enabled by functionalizing nanoparticles with specific ligands, has emerged as a promising strategy to enhance accuracy and reduce false positives. Molecular imaging, facilitated by nanotechnology, allows for real-time monitoring of cellular and molecular events, providing insights into disease mechanisms. Moreover, the miniaturization of imaging devices, a product of nanoscale components, is transforming point-of-care diagnostics and healthcare accessibility. The safety and biocompatibility of nanomaterials are also addressed, crucial for the clinical translation of these innovations.
APPLICATIONS OF NANO PARTICLES IN RESPIRATORY DISEASES
Authors: Sowmeia Ms. , Aditya Mr. , Babitha Ms. , V Rakesh
Published: June 2024

With time the blow of respiratory disorders are increasing, which is leading to the shortage of conventional drugs. To overcome this shortage new nanomedicine are discovered with the use of nanoparticles. Therefore, it is necessary to discuss the effects of drugs that are based on Nano particles, on various respiratory diseases. Nano particles proved to be very effective in treating pulmonary diseases on the basis of its intrinsic characteristics and the basic composition it had. Different kinds of nano materials like carbon nanotubes, polymeric nano particles, dendrimers, liposomes etc. reveal therapeutic effects on respiratory diseases. This can lead to new feasible remedies for different illness related to the respiratory system with an intention of increasing efficacy of the drug and reducing the side effects.
APPLICATIONS OF NATURAL POLYMERS IN NOVEL DRUG DELIVERY SYSTEMS
Authors: Sonkar Jyotsana , Deo Yadav Rahul , Kumar Niranjan Pradeep
Published: June 2024

Natural polymers have considerable attention as budding carriers being the delivery of drugs and other medicinal compounds. Natural macromolecule are versatile in medicine administration because of their inherent advantages in exceptional bioabsorbable, limited enzyme deterioration, specific inter connection with various biological molecules, and ease of moderation. The two required components of any medicament formulation are the active constitutents and filling material. Filling material assist the production of prescription and increases their biophysical properties. As excipients, macromolecules are essential in all dosage forms. Through the release of two different drug types, hydrophilic and hydrophobic, macromolecules play a significant part in the evolution of drug distribution innovation. Due to some of the negative complication and harmful effect of synthetic drugs, products from natural sources have become an essential component of the human health care system. In solid oral medication, polymers have been widely utilized as binders, diluents, breakdown, and matrix agents. Nanoscience has just begun to produce considerable strides in biomedicinal applications, including more modern medication delivery methods. Because, since that natural polymers are abundant in living world, generally bioabsorbable, recyclable, defended, and insusceptible, there has been extensive investigation into producing bioabsorbable, recyclable, micrometers devices as drug delivery. The most extensively researched and used natural materials for implementation in new drug delivery include polysaccharides, resins, along with tannins.
IMPACT OF MICRO AND NANO PLASTICS ON OCEAN ENVIRONMENT
Authors: Sengupta Subhodeep , Mridha Shubhajit , Mondal Supriyo , Moulik Soumyajit , Soumik Podder Dr.
Published: June 2024

These polymers are both purposefully produced for use in numerous sectors and are derived from the deterioration of bigger plastic objects. They have an impact on marine species at the bottom of the food chain because of how easy they can enter marine ecosystems due to their small size. These particles are consumed by phytoplankton and zooplankton, which are vital for marine life and the creation of oxygen, and this causes bioaccumulation as they rise up the food chain. This bioaccumulation has negative impacts on fish, marine mammals, and seabirds, and it may have consequences for human health if people consume seafood. Furthermore, toxic contaminants are carried by microplastics and nanoplastics, which concentrate dangerous compounds on their surfaces. These poisons have the ability to harm marine organisms' immune systems, reproductive processes, and endocrine systems. Additionally, the particles change the ocean water's physicochemical composition, influencing its temperature, transparency, and nutrient cycle. The difficulty of cleanup and mitigation is made more difficult by the dispersion of these plastics throughout broad maritime stretches. Interdisciplinary research and international partnerships are essential to addressing this issue because they will help create practical plans for reducing plastic manufacturing, improving waste management, and creating cutting-edge technology to remove existing micro- and nanoplastics from the oceans. Micro and nanoplastics have a significant, encompassing ecological, biological, and chemical impact on the ocean ecosystem. For the protection of marine ecosystems and the sustainability of our world, this issue must be addressed.
A BRIEF REVIEW OF THE ELECTRODES AND ELECTROLYTES INFLUENCING THE SUPERCAPACITOR'S BEHAVIOR
Authors: T L Soundarya , Nirmala B Dr. , Nagaraju G Dr.
Published: June 2024

Energy storage systems have recently become absolutely necessary for day-to-day existence because of energy issues. Super capacitors are among the most significant forms of energy storage devices. Supercapacitors rely on electrodes to store and release energy. Electrodes and electrolytes are crucial components that play an essential role in the performance and efficiency of the supercapacitor. Hence, for better super capacitor performance, choosing the appropriate components is of utmost importance as well. In order to understand their functionality and potential applications, various factors like their energy density, power density, and capacitance are considered. The sorts of supercapacitors, their electrodes, and their taxonomy, as well as electrolytes and the variables affecting specific capacitance, are briefly studied in the current study. It includes an extensive discussion of the importance of transition metal oxides, their doping, and their composites. Additionally, studying these components can provide insights into their efficiency and durability, allowing for improvements in their design and performance. This paper provides an overview of certain significant electrodes, their characteristics, and the electrolyte behavior affecting a specific capacitance.
GREENER SYNTHESIS & CATALYTIC APPLICATIONS OF METAL OXIDE NANOMATERIALS
Authors: Vikrant S. Palekar Dr.
Published: June 2024

There has been increasing attention on the development of green synthetic methodologies for synthesizing a wide range of nanomaterials including metal/metal oxides nanomaterial as it is observed sustainable, effective and ecological method for the application as an effective nanocatalyst. It has been well demonstrated that nanomaterials are significant class of materials that involves of an extensive range of examples with dimensions in the range of 1 to 100 nm size. There has been an incredible improvement in recent years, for the synthesis of nano and microparticles with selective shape and size because of their exceptional physical-chemical properties. There has been a need to develop techniques to reduce the destructive effects associated with the traditional methods of synthesis for nanoparticles commonly utilized in laboratories and industry. To develop greener approaches for the synthesis of nanomaterials it has been observed that transition-metal nanoparticles possess a wide scope of applications as they carry multiple oxidation states and improved surface area which proves a better reactivity when compared to their bulk counterpart and rendering them an interesting research topic. This chapter aims to explore greener synthesis of transition-metal oxide-based nanomaterials mainly involving Cu2O, NiO, & MgO nanomaterials with their characterization by different spectral techniques. Moreover, the application of Copper Oxide, Nickel Oxide & Magnesium oxide nanomaterials in organic transformations suggests a greener pathway for the synthesis of varied organic compounds with effective results.
ROLE OF BRACHYTHERAPY IN KELOIDS
Authors: Kang Dr. Manraj Singh , Kaur Dr. Taranjeet , Mittal Dr. Shubham , Garg Dr. Pardeep
Published: June 2024

Radiation therapy is the last option in the treatment of resistant keloids. This puts a huge fin ncial and logistical burden on both patients and the healthcare system. Radiotherapy has achieved good and cosmetic results at a lower cost. The ideal treatment plan consists of complete removal of the keloid followed by rapid administration of the first dose of radiation. The most commonly used techniques areexternal beam radiation, low dose rate brachytherapy, and high dose rate brachytherapy. Brachytherapy has fewer side effects and lower costs than external radiation. Although more studies are needed, an effective radiation dose (BED) 20-30Gy, such as 2x6Gy, appears to be sufficient in most cases. The most common complications are erythema, temporary and permanent pigmentation disorders, and telangiectasia. While mentioning the risk of secondary cancers occurring in the medical field, only a few cases have been identified, none of which resulted from brachytherapy.
AN EXPERIMENTAL STUDY TO EVALUATE THE KRIMIGHNA EFFECT OF DHOOPANA ALONG WITH THE STANDARDIZATION OF DHOOPANA FORMULATIONS
Authors: Walia Dr. Mehak , Thakur Dr. Tek Chand , Dhar Dr. Prasenjit , Srivastava Dr. Akhilesh Kumar
Published: June 2024

The air around us contains a large number of microorganisms (Krimi) and it can get contaminated by these microorganisms. Thus it carries a lot of significance to disinfect the area where we reside, which in turn can result in the prevention of many infectious diseases. To get prevention from Krimi (microbes), Rakshoghnavidhan is indicated in our classics [1]. In this various medicinal plants were burnt on fire and the smoke generated from it was used for sterilization of different areas where chances of infections are more. In the present context Dhoopana Yoga was prepared out of drugs indicated for Krimighna Karma .Rooted in the holistic system of Ayurveda, the study explores the ancient healing practice of Dhoopana, focusing on its reputed ability to repel harmful entities, known as the Krimighna effect. Concurrently, the research endeavors to establish standardized formulations, addressing the challenge of variability within traditional practices. The study blends historical insights with modern scientific rigor, employing laboratory experiments and real-world observations to assess the efficacy of diverse Dhoopana blends. The paper also outlines a pathway for achieving standardization, harmonizing herb selection, ratios, and procedural consistency. This chapter serves as a bridge between ancient wisdom and contemporary scientific inquiry, inviting discourse and contributing to the preservation and evolution of traditional healing practices.
EVIDENCE BASED MANAGEMENT OF ORAL LESIONS
Authors: Amena Dr Mehroz
Published: June 2024

Evidence based practice have been known since long times but have gained importance recently. Evidence based medicine is a vast phenomena used in various aspects of dentistry. This chapter aims to focus on the diagnosis and management of oral lesions commonly encountered in dental practice. The diagnosis and treatment of various oral lesions and conditions have always lacked proper clinical evidence and support and therefore needs a standard approach for their management. This chapter provides a brief description about evidence based practice, further it also brings out the various evidence based management strategies in the treatment of oral diseases. The methods discussed in this chapter can serve as a framework for further evaluation and treatment of these conditions.
THE FUTURISTIC TRENDS IN DENTAL SCIENCES
Authors: Kalmath Dr. Bhuvaneshwari
Published: June 2024

Introduction to new book why? When already so many books exist at the same topic? It is because; in the first place every author is highly appreciated and their work is recognized. Each of the books has given the experienced author to share their knowledge and research skill for the betterment of next generation students. With my work of teaching experience and my mentor’s guidance I present this topic in a simplicity style and adaptive by every student in academics and daily practice.
EMERGING AND RECENT TRENDS AND FUTURE DIRECTIONS OF DENTAL RESEARCH IN DIGITAL ERA
Authors: Noor Dr. Umama
Published: June 2024

This chapter explores the dynamic landscape of dental research in the digital era, delving into recent trends and paving the way for future directions. From advancements in digital imaging to innovative diagnostic tools, the chapter examines the transformative impact of technology on dental practices. Insights into data-driven approaches, artificial intelligence, and personalized treatments contribute to a comprehensive overview, offering a glimpse into the promising future of digital dentistry research. In this comprehensive exploration of dental research within the digital era, the chapter not only examines recent trends but also anticipates the future trajectory of the field. The opinion letter embedded within the chapter focuses on the estimated top five trends and innovations with the potential to decisively influence the direction of dental research. The chapter scrutinizes the impact of rapid prototyping (RP), shedding light on its transformative role in dental applications. Additionally, the integration of augmented and virtual reality (AR/VR) is explored for its potential to revolutionize dental education, treatment planning, and patient engagement. Artificial intelligence (AI) and machine learning (ML) take center stage as the chapter analyzes their growing importance in data analysis, diagnostics, and treatment optimization. The discussion extends to personalized (dental) medicine, highlighting how advancements in genetic research and tailored treatment approaches are reshaping the landscape of oral healthcare. Furthermore, the chapter delves into the fifth trend of tele-healthcare, discussing its role in expanding accessibility to dental services through remote consultations and virtual treatment monitoring. Ethical considerations and data security within this digital paradigm are also addressed, emphasizing the need for a balanced and responsible approach. As the chapter unfolds, it provides valuable insights into collaborative efforts between dental researchers, technologists, and practitioners. These collaborations foster innovation, pushing the boundaries of what is possible in digital dentistry. By analyzing the current landscape and projecting future developments, the chapter, with its opinion letter, serves as a comprehensive guide for researchers and practitioners navigating the evolving terrain of dental research in the digital age.
CURRENT TRENDS IN REGENERATIVE ENDODONTICS THERAPY (RET)
Authors: Narayanan Dr K Sathya , Amalavathy. R Dr. Kurinji , Aravinthan. S Dr.
Published: June 2024

The developing dentition is vulnerable to potential risks of pulp necrosis caused by factors such as caries, trauma, and developmental anomalies like Dens evaginatus and invaginatus. Caries, a multifactorial disease, entails the infiltration of bacteria and their by-products into the pulp, triggering inflammation and fibrosis of pulp tissue. In cases where bacteria persist, chronic inflammation may arise, resulting in the necrosis of specific pulp tissue. Prolonged inflammation or recurring insults diminish the pulp's intrinsic capacity for self-repair, ultimately resulting in the spread of necrosis throughout the entire pulp.
RECENT TRENDS IN NURSING RESEARCH & EDUCATION
Authors: Garg Dr. Ruchika , Kaur Dr. Harpreet
Published: June 2024

Nurse is an important member of a hospital or health care organization. Role of nurses in providing quality healthcare is most essential and they are considered angel on the earth. In a health care set-up has been demonstrated by increase in patient mortality and morbidity. There have been several advances in the nursing education & research. Several recent courses in Nursing have been initiated to give a boost to nursing career.
DOSAGE FORM DESIGN
Authors: Khan Zuber , Mumtaz Mrs. , Saifi Mohd Anas , Ahamad Rizwan , Ali Asad
Published: June 2024

Designing pharmaceutical dosage forms is a crucial field that tries to provide convenient, reliable, and safe drug delivery systems. By spanning the gap between active medication ingredients and their administration, this multidisciplinary sector ensures the best possible therapeutic results. Drug qualities, patient characteristics, administration method, release kinetics, and manufacturing considerations are taken into account while designing dosage forms. The design must take into consideration the various demands of patients across age groups, from difficulties with compliance in young children to changes in drug absorption in geriatric populations. The best dosage forms should be stable, easy to administer safely, accurate in their dosing, and well tolerated by patients. Dosage form design is primarily driven by biopharmaceutics, a patient-centred approach, release kinetics, excipient selection, manufacturing, safety, and cost-effectiveness. Novel possibilities for adjusting drug administration to specific needs have been made possible by cutting-edge technologies and personalised medicine. Dosage forms are classified depending on their physical form and mode of administration and include solid, liquid, semi-solid, and gaseous forms. Pre-formulation studies are necessary for gathering important data on the properties of the medicine and its interactions with excipients. Pharmaceutical researchers working with clinicians have the potential to develop revolutionary medication delivery methods, improving patient care and treatment effectiveness.
RADIOCHEMISTRY
Authors: Lata Dr. Suman , Gagandeep Mr. , Kaur Hardeep
Published: June 2024

The fascinating field of research known as radiochemistry focuses on the investigation of radioactive materials and related behaviours. To understand the complex interactions between matter and radiation, a multidisciplinary subject called nuclear science, chemistry, and physics are used. The fundamental process of radiochemistry is radioactive decay, in which unstable atomic nuclei transform on their own and generate alpha, beta, and gamma radiation. Applications such as nuclear energy production, nuclear medicine, and environmental analysis all have their roots in our understanding of radioactive decay. The study of nuclear reactions, including both fusion and fission processes, is a key component of radiochemistry. Archaeologists and geologists can determine the age of ancient materials and artefacts using radiocarbon dating, one of radiochemistry's outstanding uses. Radiochemistry is set to open new doors as research continues. Radiochemistry is poised to open up new pathways in environmental, healthcare, and energy science as research advances, helping to create a deeper understanding of the natural world.