bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF file - 126K, Activity of FRAX-597 against group A and group B Paks
Supplementary Figure 4 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: March 2023

PDF - 364K, Stromal or epithelial specific deletion of PR-A and PR-B.
Supplementary Figure 1 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: March 2023

PDF - 250K, Histology of PTENKO tumors and hormone supplementation in treated mice.
Supplementary Figures 1-7, Tables 1-6 from miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma
Authors: Jones Kevin B. , Salah Zaidoun , Del Mare Sara , Galasso Marco , Gaudio Eugenio , Nuovo Gerard J. , Lovat Francesca , LeBlanc Kimberly , Palatini Jeff , Randall R. Lor , Volinia Stefano , Stein Gary S. , Croce Carlo M. , Lian Jane B. , Aqeilan Rami I.
Published: March 2023

PDF file - 2MB
Supplementary Table 3 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: March 2023

PDF file - 69K, Summary of IHC staining for HBx, Shh, Ihh, Gli2 and PTCH1 among HBV infected patients with HCC
Supplementary Figure 4 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: March 2023

PDF file - 2.3MB
Supplementary Tables 1-2 from ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Authors: Faget Julien , Bendriss-Vermare Nathalie , Gobert Michael , Durand Isabelle , Olive Daniel , Biota Cathy , Bachelot Thomas , Treilleux Isabelle , Goddard-Leon Sophie , Lavergne Emilie , Chabaud Sylvie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: March 2023

PDF file - 103K, Table S1: Clinical characteristic of the cohort of BT patients enrolled for TMA analysis (n=120) Table S2: clones of mAbs used for the multi-parametric flow cytometry analyses
Supplementary Figure 2 from Tumor-Derived Chemokine CCL5 Enhances TGF-β–Mediated Killing of CD8+ T Cells in Colon Cancer by T-Regulatory Cells
Authors: Chang Li-Yuan , Lin Yung-Chang , Mahalingam Jayashri , Huang Ching-Tai , Chen Ten-Wen , Kang Chiao-Wen , Peng Hui-Min , Chu Yu-Yi , Chiang Jy-Ming , Dutta Avijit , Day Yuan-Ji , Chen Tse-Ching , Yeh Chau-Ting , Lin Chun-Yen
Published: March 2023

PDF file - 78K
Supplementary Figures 1-5 from Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma
Authors: Chan Isaac S. , Guy Cynthia D. , Chen Yuping , Lu Jiuyi , Swiderska-Syn Marzena , Michelotti Gregory A. , Karaca Gamze , Xie Guanhua , Krüger Leandi , Syn Wing-Kin , Anderson Blair R. , Pereira Thiago A. , Choi Steve S. , Baldwin Albert S. , Diehl Anna Mae
Published: March 2023

PDF file - 127K, S1. Panc 10.05 cells do not generate functional Hh ligands. S2. Other malignant hepatoma lines can increase MF Hh and glycolytic activity. S3. Summary of glycolytic metabolism. S4. MF-derived lactate provides energy source for lipogenesis in other malignant hepatoma lines. S5. Schematic of alterations in hepatoma cells due to release of metabolic end products by glycolytic MF
Supplementary Figure 1 from Host Immune Defense Peptide LL-37 Activates Caspase-Independent Apoptosis and Suppresses Colon Cancer
Authors: Ren Shun X. , Cheng Alfred S.L. , To Ka F. , Tong Joanna H.M. , Li May S. , Shen Jin , Wong Clover C.M. , Zhang Lin , Chan Ruby L.Y. , Wang Xiao J. , Ng Simon S.M. , Chiu Lawrence C.M. , Marquez Victor E. , Gallo Richard L. , Chan Francis K.L. , Yu Jun , Sung Joseph J.Y. , Wu William K.K. , Cho Chi H.
Published: March 2023

PDF file - 4.4MB, Figure S1 Apoptogenic function and mechanism of LL-37 in LoVo colon cancer cells
Supplementary Figure 2 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: March 2023

PDF file - 2.2MB, (A) Cell monolayers were infected with 100 viral paticles /cell (VP/cell) and 24 hours later cells were analyzed by flow-cytometry measuring Annexin-V expression. Results are presented as percentage of positive cells relative to Mock uninfected cells. **, P<0.01. (B) CD40 expression is shown in brown in A549 and EJ tumors. Pictures were taken with an Axioplan Microscope equipped with a camera Axiocam at a magnification of 10x. (C) Tumors from nude mice bearing either A549 tumors (left panel) or EJ tumors (right panel) injected with viruses were analyzed for viral load. Quantitative PCR was performed for E4 sequence and values were normalized to human beta-actin gene.. The real-time PCR conditions were as described in (31). All samples were tested in duplicate. Results are presented as mean from all mice +SEM. **, P<0.01.
Supplementary Table S1 from Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity
Authors: Ishii Nobuya , Harada Naoki , Joseph Eric W. , Ohara Kazuhiro , Miura Takaaki , Sakamoto Hiroshi , Matsuda Yutaka , Tomii Yasushi , Tachibana-Kondo Yukako , Iikura Hitoshi , Aoki Toshihiro , Shimma Nobuo , Arisawa Mikio , Sowa Yoshihiro , Poulikakos Poulikos I. , Rosen Neal , Aoki Yuko , Sakai Toshiyuki
Published: March 2023

Supplementary Table S1 - PDF file 60K, The correlation coefficients of anti-proliferative activity of 21 antitumor agents including CH5126766 in a 20-cell line panel
Supplementary Figure 2 from Loss of PPP2R2A Inhibits Homologous Recombination DNA Repair and Predicts Tumor Sensitivity to PARP Inhibition
Authors: Kalev Peter , Simicek Michal , Vazquez Iria , Munck Sebastian , Chen Liping , Soin Thomas , Danda Natasha , Chen Wen , Sablina Anna
Published: March 2023

PDF file - 101K, Automated image analysis of Rad51 immunostaining using In Cell Analyzer 2000
Supplementary Figure S3 from Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity
Authors: Ishii Nobuya , Harada Naoki , Joseph Eric W. , Ohara Kazuhiro , Miura Takaaki , Sakamoto Hiroshi , Matsuda Yutaka , Tomii Yasushi , Tachibana-Kondo Yukako , Iikura Hitoshi , Aoki Toshihiro , Shimma Nobuo , Arisawa Mikio , Sowa Yoshihiro , Poulikakos Poulikos I. , Rosen Neal , Aoki Yuko , Sakai Toshiyuki
Published: March 2023

Supplementary Figure S3 - PDF file 63K, Antitumor activity of CH5126766 (A) and PD0325901 (B) in HCT116 xenograft tumor for determination of ED50
Supplementary Methods , Figure Legends 1-17 from Autophagy Control by the VEGF-C/NRP-2 Axis in Cancer and Its Implication for Treatment Resistance
Authors: Stanton Marissa J. , Dutta Samikshan , Zhang Heyu , Polavaram Navatha S. , Leontovich Alexey A. , Hönscheid Pia , Sinicrope Frank A. , Tindall Donald J. , Muders Michael H. , Datta Kaustubh
Published: March 2023

PDF file - 70K
Supplementary Table 1 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer
Authors: Wang Qingfei , Li Shau-Hsuan , Wang Hai , Xiao Yi , Sahin Ozgur , Brady Samuel W. , Li Ping , Ge Hailiang , Jaffee Elizabeth M. , Muller William J. , Hortobagyi Gabriel N. , Yu Dihua
Published: March 2023

PDF file - 82K, Primer sequences for quantitative real-time reverse transcription-PCR
Supplementary Figure 3 from The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA
Authors: Rabellino Andrea , Carter Brandon , Konstantinidou Georgia , Wu Shwu-Yuan , Rimessi Alessandro , Byers Lauren A. , Heymach John V. , Girard Luc , Chiang Cheng-Ming , Teruya-Feldstein Julie , Scaglioni Pier Paolo
Published: March 2023

PDF file - 126K
Supplementary Figure 3 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer
Authors: Wang Qingfei , Li Shau-Hsuan , Wang Hai , Xiao Yi , Sahin Ozgur , Brady Samuel W. , Li Ping , Ge Hailiang , Jaffee Elizabeth M. , Muller William J. , Hortobagyi Gabriel N. , Yu Dihua
Published: March 2023

PDF file - 410K, Histological and immunohistochemical analysis of tumors derived from PTEN-/-/ErbB2KI mice receiving single or combination treatment
Supplementary Table 1 from S100A7 Enhances Mammary Tumorigenesis through Upregulation of Inflammatory Pathways
Authors: Nasser Mohd W. , Qamri Zahida , Deol Yadwinder S. , Ravi Janani , Powell Catherine A. , Trikha Prashant , Schwendener Reto A. , Bai Xue-Feng , Shilo Konstantin , Zou Xianghong , Leone Gustavo , Wolf Ronald , Yuspa Stuart H. , Ganju Ramesh K.
Published: March 2023

PDF file - 88K
Supplementary Figure 8 from Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence
Authors: Cui Hang , Kong Yahui , Xu Mei , Zhang Hong
Published: March 2023

PDF file - 486K, Data showing Notch3 induces senescence in human tumor cells.
Supplementary Methods from Defining NOTCH3 Target Genes in Ovarian Cancer
Authors: Chen Xu , Thiaville Michelle M. , Chen Li , Stoeck Alexander , Xuan Jianhua , Gao Min , Shih Ie-Ming , Wang Tian-Li
Published: March 2023

PDF file - 25K
Supplementary Figure 6 from Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence
Authors: Cui Hang , Kong Yahui , Xu Mei , Zhang Hong
Published: March 2023

PDF file - 93K, Data showing Notch1, Notch2 and Notch4 expression in human breast cancer and melanoma samples.
Supplementary Figure 2 from Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence
Authors: Cui Hang , Kong Yahui , Xu Mei , Zhang Hong
Published: March 2023

PDF file - 30K, Data showing extended replicative lifespan in LF1 cells after shRNA knockdown of Notch3.
Supplementary Figures 1-7 from Pak1 Kinase Links ErbB2 to β-Catenin in Transformation of Breast Epithelial Cells
Authors: Arias-Romero Luis E. , Villamar-Cruz Olga , Huang Min , Hoeflich Klaus P. , Chernoff Jonathan
Published: March 2023

PDF File - 825K, Effects of Pak depletion on proliferation and survival signaling pathways in breast cancer cells.
Supplementary Figure 1 from p38 MAPK in Myeloma Cells Regulates Osteoclast and Osteoblast Activity and Induces Bone Destruction
Authors: He Jin , Liu Zhiqiang , Zheng Yuhuan , Qian Jianfei , Li Haiyan , Lu Yong , Xu Jingda , Hong Bangxing , Zhang Mingjun , Lin Pei , Cai Zhen , Orlowski Robert Z. , Kwak Larry W. , Yi Qing , Yang Jing
Published: March 2023

PDF file - 81K, Schematic representation of the mechanism underlying myeloma cell p38-induced osteoclastogenesis activation and osteoblastogenesis inhibition
Supplementary Figure 8 from Targeting Pioneering Factor and Hormone Receptor Cooperative Pathways to Suppress Tumor Progression
Authors: Shah Supriya , Prasad Shikha , Knudsen Karen E.
Published: March 2023

PDF file - 1.4MB
Supplementary Figure 4 from Immunogenic Tumor Cell Death Induced by Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma
Authors: Suzuki Yoshiyuki , Mimura Kousaku , Yoshimoto Yuya , Watanabe Mitsuaki , Ohkubo Yu , Izawa Shinichirou , Murata Kazutoshi , Fujii Hideki , Nakano Takashi , Kono Koji
Published: March 2023

PDF file - 203K, Surface expression of calreticulin on TE2 after 30Gy-irradiation (10Gy irradiation on day 1, day 2, and day 3) or chemotherapy (5FU + CDDP + Docetaxel on day 1)
Supplementary Figure 4 from A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis
Authors: Doornebal Chris W. , Klarenbeek Sjoerd , Braumuller Tanya M. , Klijn Christiaan N. , Ciampricotti Metamia , Hau Cheei-Sing , Hollmann Markus W. , Jonkers Jos , de Visser Karin E.
Published: March 2023

PDF file - 36K, S4. Genomic profiles of paired lung- and lymph node metastases suggest that metastatic dissemination to these organs is not driven by recurrent, tissue specific copy number aberrations.
Supplementary Figure 2 from A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis
Authors: Doornebal Chris W. , Klarenbeek Sjoerd , Braumuller Tanya M. , Klijn Christiaan N. , Ciampricotti Metamia , Hau Cheei-Sing , Hollmann Markus W. , Jonkers Jos , de Visser Karin E.
Published: March 2023

PDF file - 394K, S2. Genomic profiles of K14cre;Cdh1F/F;Trp53F/F derived donor mILCs are highly conserved in transplanted recipient outgrowths.
Supplementary Figure 4 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: March 2023

PDF file - 85K, Lung tumor cells and CAFs induce a of CAF-like phenotype in NFs
Supplementary Figure 3 from Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non–Small Cell Lung Cancer In Vivo
Authors: Vicent Silvestre , Sayles Leanne C. , Vaka Dedeepya , Khatri Purvesh , Gevaert Olivier , Chen Ron , Zheng Yanyan , Gillespie Anna K. , Clarke Nicole , Xu Yue , Shrager Joseph , Hoang Chuong D. , Plevritis Sylvia , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: March 2023

PDF file - 20K, Survival prognosis of a mouse CAF-secretory gene signature in human NSCLC
Supplementary Results from Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin–Positive Metastatic Human Melanoma Xenografts
Authors: Moschetta Michele , Pretto Francesca , Berndt Alexander , Galler Kerstin , Richter Petra , Bassi Andrea , Oliva Paolo , Micotti Edoardo , Valbusa Giovanni , Schwager Kathrin , Kaspar Manuela , Trachsel Eveline , Kosmehl Hartwig , Bani Maria Rosa , Neri Dario , Giavazzi Raffaella
Published: March 2023

PDF file - 63K
Supplementary Figure 5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: March 2023

PDF file - 286K
Supplementary Figure 3 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Authors: Chen Runqiang , Yang Qingkai , Lee Jiing-Dwan
Published: March 2023

PDF file - 234K
Supplementary Figure 3 from Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
Authors: Cipponi Arcadi , Mercier Marjorie , Seremet Teofila , Baurain Jean-François , Théate Ivan , van den Oord Joost , Stas Marguerite , Boon Thierry , Coulie Pierre G. , van Baren Nicolas
Published: March 2023

PDF file - 131K, Procedure for the preparation of immunoglobulin VDJC1 libraries
Supplementary Figure 3 from eIF4E/4E-BP Ratio Predicts the Efficacy of mTOR Targeted Therapies
Authors: Alain Tommy , Morita Masahiro , Fonseca Bruno D. , Yanagiya Akiko , Siddiqui Nadeem , Bhat Mamatha , Zammit Domenick , Marcus Victoria , Metrakos Peter , Voyer Lucie-Anne , Gandin Valentina , Liu Yi , Topisirovic Ivan , Sonenberg Nahum
Published: March 2023

PDF file - 2.9MB, Figure S3 contains data that show that cells with elevated eIF4E expression exhibit resistance to asTORi. These data complement the main figures of the manuscript
Supplementary Figures 1-12 from LIN28 Expression in Malignant Germ Cell Tumors Downregulates let-7 and Increases Oncogene Levels
Authors: Murray Matthew J. , Saini Harpreet K. , Siegler Charlotte A. , Hanning Jennifer E. , Barker Emily M. , van Dongen Stijn , Ward Dawn M. , Raby Katie L. , Groves Ian J. , Scarpini Cinzia G. , Pett Mark R. , Thornton Claire M. , Enright Anton J. , Nicholson James C. , Coleman Nicholas
Published: March 2023

PDF - 492K, Supplementary Figure 1: Levels of the nine members of the let-7 family in pediatric malignant-GCTs. Supplementary Figure 2: PCR quantification of let-7e, LIN28 and LIN28B in malignant-GCTs.Supplementary Figure 3: Sylamer analysis of up-regulated genes in pediatric and adult malignant-GCTs. Supplementary Figure 4: Correlations between levels of let-7 and mRNA targets. Supplementary Figure 5: PCR quantification of HMGA2 in pediatric malignant-GCTs. Supplementary Figure 6: PCR validation of expression of selected let-7 mRNA targets in pediatric malignant-GCTs. Supplementary Figure 7: Effects of LIN28 depletion in malignant-GCT cells. Supplementary Figure 8: Independent confirmation of specific effects of LIN28 depletion in malignant-GCT cells. Supplementary Figure 9: Effects of let-7e mimic in malignant-GCT cells. Supplementary Figure 10: Relationships between MYCN and C-MYC versus LIN28 and LIN28B in malignant-GCTs. Supplementary Figure 11: MYCN depletion in malignant-GCTs (S11). Supplementary Figure 12: Schematic of the LIN28/let-7 axis in malignant-GCTs.
Supplementary Methods from Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1–Dependent Repression of BMP-5
Authors: Romagnoli Mathilde , Belguise Karine , Yu Ziyang , Wang Xiaobo , Landesman-Bollag Esther , Seldin David C. , Chalbos Dany , Barillé-Nion Sophie , Jézéquel Pascal , Seldin Margaret L. , Sonenshein Gail E.
Published: March 2023

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Supplementary Figure Legends from LIN28 Expression in Malignant Germ Cell Tumors Downregulates let-7 and Increases Oncogene Levels
Authors: Murray Matthew J. , Saini Harpreet K. , Siegler Charlotte A. , Hanning Jennifer E. , Barker Emily M. , van Dongen Stijn , Ward Dawn M. , Raby Katie L. , Groves Ian J. , Scarpini Cinzia G. , Pett Mark R. , Thornton Claire M. , Enright Anton J. , Nicholson James C. , Coleman Nicholas
Published: March 2023

PDF - 59K.
Supplementary Methods from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: March 2023

PDF file - 78K
Supplementary Methods, Table 1 from Reconsidering the Paradigm of Cancer Immunotherapy by Computationally Aided Real-time Personalization
Authors: Kogan Yuri , Halevi–Tobias Karin , Elishmereni Moran , Vuk-Pavlović Stanimir , Agur Zvia
Published: March 2023

PDF file - 201K, The contents of the document: 1. Model equations for the vaccine and the maturing DCs 2. Formal description of the algorithm for in-treatment therapy personalization 3. Success-of-validation criteria 4. Model comparison grade and parameters for SOV criterion 5. Selecting the best performing SOV criterion 6. Table S1
Supplementary Tables 1 - 8 from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: March 2023

PDF file, 194K, Table S1 EPCs cf Lineage Depleted Cells. Table S2 EPCs cf Myeloid Progenitors. Table S3 Small RNAs Regulated in Response to Tumor. Table S4 Tumor Vasculature cf Normal Vasculature. Table S5A Tumor Vasculature cf Normal Vasculature (Log2 Normalised Expression), Table S5B Tumor Vasculature cf Normal Vasculature (Log2 Normalised Expression), Table S5C Tumor Vasculature cf Normal Vasculature (Log2 Normalised Expression), following cherry exclusion. Table S7A Human Tumor Vessels/Field, Table S7B VEGF Induction of Human ECs, Table S7C Tumor-Conditioned Media Induction of Human Cell Lines. Table S8A Tube Number and Length Mouse ECs: anti-miR-10b, Table S8B Tube Number and Length Human ECs: anti-miR-10b, Table S8C Tube Number and Length Mouse ECs: anti-miR-196b, Table S8D Tube Number and Length Human ECs: anti-miR-196b, Table S8E Wound Healing Assay Mouse ECs: anti-miR-10b, Table S8F Wound Healing Human ECs: anti-miR-10b, Table S8G Wound Healing Mouse ECs: anti-miR-196b, Table S8H Wound Healing Human ECs: anti-miR-196b.
Supplementary Figure 4 from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: March 2023

PDF file - 1514K, Supplemental Figure 4: Plk and Aurk inhibitors enhance sensitivity to radiation.
Supplementary Figures from C1GALT1 Enhances Proliferation of Hepatocellular Carcinoma Cells via Modulating MET Glycosylation and Dimerization
Authors: Wu Yao-Ming , Liu Chiung-Hui , Huang Miao-Juei , Lai Hong-Shiee , Lee Po-Huang , Hu Rey-Heng , Huang Min-Chuan
Published: March 2023

PDF file, 119K, Supplementary Figure S1. Statistical analysis of C1GALT1 expression in tissue microarrays. Supplementary Figure S2. Immunofluorescence staining of C1GALT1 in HCC cells. Supplementary Figure S3. Effects of C1GALT1 on cell cycles. Supplementary Figure S4. Establishment of stable transfectants of C1GALT1 knockdown cells. Supplementary Figure S5. Expression of C1GALT1 in the xenografted tumors. Supplementary Figure S6. C1GALT1 regulates HGF-induced migration and invasion of HCC cells. Supplementary Figure S7. MET is decorated with short O-glycans.
Supplementary Table 2 from Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated Gliomas
Authors: Jin Genglin , Reitman Zachary J. , Duncan Christopher G. , Spasojevic Ivan , Gooden David M. , Rasheed B. Ahmed , Yang Rui , Lopez Giselle Y. , He Yiping , McLendon Roger E. , Bigner Darell D. , Yan Hai
Published: March 2023

PDF file-23KB, D-2HG in cell line lysate samples, as assessed by LC-MS/M
Supplementary Figures from A Synthetic Lethality–Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1
Authors: Oike Takahiro , Ogiwara Hideaki , Tominaga Yuichi , Ito Kentaro , Ando Osamu , Tsuta Koji , Mizukami Tatsuji , Shimada Yoko , Isomura Hisanori , Komachi Mayumi , Furuta Koh , Watanabe Shun-Ichi , Nakano Takashi , Yokota Jun , Kohno Takashi
Published: March 2023

PDF file, 1764K, Supplementary Figure S1. Immunohistochemical staining for BRG1 and BRM in cancer cell lines. Supplementary Figure S2. E431* and E608* Supplementary Figure S3. Fluorescence in situ hybridization for the detection of FGFR1 amplification in a case of squamous lung cell carcinoma. Supplementary Figure S4. Immunoblot analysis of SWI/SNF and ACF chromatinremodeling proteins. Supplementary Figure S5. Survival of H1299 (BRG1-deficient) and HeLa (BRG1-proficient) cells after shRNA-mediated knockdown of BRM (shBRM). Supplementary Figure S6. The effects of BRM knockdown on the morphologies of BRG1-deficient and proficient cancer cells. Supplementary Figure S7. Effect of BRM knockdown on the induction of senescence in BRG1-deficient and -proficient non-small-cell lung carcinoma cells.
Supplementary Methods from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: March 2023

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Supplementary Figure 4 from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: March 2023

PDF file, 322K, Obesity-like stromal cells did not increase responsiveness of endothelial cells.
Supplementary Figure 1 from Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Authors: Arendt Lisa M. , McCready Jessica , Keller Patricia J. , Baker Dana D. , Naber Stephen P. , Seewaldt Victoria , Kuperwasser Charlotte
Published: March 2023

PDF file, 945K, Adipose stromal cells synthesize lipid droplets in response to adipogenic media.
Supplementary Table 2 from PIK3CA Mutation H1047R Is Associated with Response to PI3K/AKT/mTOR Signaling Pathway Inhibitors in Early-Phase Clinical Trials
Authors: Janku Filip , Wheler Jennifer J. , Naing Aung , Falchook Gerald S. , Hong David S. , Stepanek Vanda M. , Fu Siqing , Piha-Paul Sarina A. , Lee J. Jack , Luthra Rajyalakshmi , Tsimberidou Apostolia M. , Kurzrock Razelle
Published: March 2023

PDF file - 70K, Co-existing PIK3CA and KRAS mutations
Supplementary Table from Mesenchymal CD44 Expression Contributes to the Acquisition of an Activated Fibroblast Phenotype via TWIST Activation in the Tumor Microenvironment
Authors: Spaeth Erika L. , Labaff Adam M. , Toole Bryan P. , Klopp Ann , Andreeff Michael , Marini Frank C.
Published: March 2023

PDF file, 271K, Primers used for PCR.
Supplementary Figure S1 from Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2–Dependent Mechanisms
Authors: Mao Yumeng , Poschke Isabel , Wennerberg Erik , Pico de Coaña Yago , Egyhazi Brage Suzanne , Schultz Inkeri , Hansson Johan , Masucci Giuseppe , Lundqvist Andreas , Kiessling Rolf
Published: March 2023

Supplementary Figure S1 - PDF file 47K, Melanoma-educated monocytes phenotypically resemble myeloid-derived suppressor cells
Supplemental Figure S4 from Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2–Dependent Mechanisms
Authors: Mao Yumeng , Poschke Isabel , Wennerberg Erik , Pico de Coaña Yago , Egyhazi Brage Suzanne , Schultz Inkeri , Hansson Johan , Masucci Giuseppe , Lundqvist Andreas , Kiessling Rolf
Published: March 2023

PGE2 receptor EP3 is responsible for the activation of STAT-3 signaling on MDSC-like cells.
Supplementary Figure and Table Legends from PanIN-Specific Regulation of Wnt Signaling by HIF2α during Early Pancreatic Tumorigenesis
Authors: Criscimanna Angela , Duan Li-Juan , Rhodes Julie A. , Fendrich Volker , Wickline Emily , Hartman Douglas J. , Monga Satdarshan P.S. , Lotze Michael T. , Gittes George K. , Fong Guo-Hua , Esni Farzad
Published: March 2023

Supplementary Figure and Table Legends�- PDF file 93K, Legend for Supplemental Tables S1-S2 and Supplemental Figures S1-S5
Supplemental Figure S1 from Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2–Dependent Mechanisms
Authors: Mao Yumeng , Poschke Isabel , Wennerberg Erik , Pico de Coaña Yago , Egyhazi Brage Suzanne , Schultz Inkeri , Hansson Johan , Masucci Giuseppe , Lundqvist Andreas , Kiessling Rolf
Published: March 2023

Melanoma-educated monocytes phenotypically resemble myeloid-derived suppressor cells.
Supplementary Information from NSD2 Is Recruited through Its PHD Domain to Oncogenic Gene Loci to Drive Multiple Myeloma
Authors: Huang Zheng , Wu Haiping , Chuai Shannon , Xu Fiona , Yan Feng , Englund Nathan , Wang Zhaofu , Zhang Hailong , Fang Ming , Wang Youzhen , Gu Justin , Zhang Man , Yang Teddy , Zhao Kehao , Yu Yanyan , Dai Jingquan , Yi Wei , Zhou Shaolian , Li Qian , Wu Jing , Liu Jun , Wu Xu , Chan Homan , Lu Chris , Atadja Peter , Li En , Wang Yan , Hu Min
Published: March 2023

PDF file, 153K.
Supplementary Figure Legend from Tumor Suppressor Function of the Plasma Glutathione Peroxidase Gpx3 in Colitis-Associated Carcinoma
Authors: Barrett Caitlyn W. , Ning Wei , Chen Xi , Smith Jesse Joshua , Washington Mary K. , Hill Kristina E. , Coburn Lori A. , Peek Richard M. , Chaturvedi Rupesh , Wilson Keith T. , Burk Raymond F. , Williams Christopher S.
Published: March 2023

PDF file - 122K
Supplementary Figure 2 from Tumor Suppressor Function of the Plasma Glutathione Peroxidase Gpx3 in Colitis-Associated Carcinoma
Authors: Barrett Caitlyn W. , Ning Wei , Chen Xi , Smith Jesse Joshua , Washington Mary K. , Hill Kristina E. , Coburn Lori A. , Peek Richard M. , Chaturvedi Rupesh , Wilson Keith T. , Burk Raymond F. , Williams Christopher S.
Published: March 2023

PDF file - 1974K, Gpx3 expression is not increased in tumor compared to normal tissue. Normal and tumor tissue mRNA expression of Gpx3 in WT normal adjacent and WT tumor tissue post-AOM/DSS. Error bars represent standard error of four mice performed in triplicate. P=n.s.
Supplementary Figure 1 from Tumor Suppressor Function of the Plasma Glutathione Peroxidase Gpx3 in Colitis-Associated Carcinoma
Authors: Barrett Caitlyn W. , Ning Wei , Chen Xi , Smith Jesse Joshua , Washington Mary K. , Hill Kristina E. , Coburn Lori A. , Peek Richard M. , Chaturvedi Rupesh , Wilson Keith T. , Burk Raymond F. , Williams Christopher S.
Published: March 2023

PDF file - 2063K, Gpx3 is decreased in plasma of mice subjected to the AOM/DSS protocol. Western blot of Gpx3 protein expression in plasma from WT water treated and AOM/DSS treated mice (top). Quantification is presented as fold change intensity and the graph (bottom) displays plasma Gpx3 protein in the mice shown in the western blot above. P=0.046.
Supplementary Figure 1 from ATR Inhibition Broadly Sensitizes Ovarian Cancer Cells to Chemotherapy Independent of BRCA Status
Authors: Huntoon Catherine J. , Flatten Karen S. , Wahner Hendrickson Andrea E. , Huehls Amelia M. , Sutor Shari L. , Kaufmann Scott H. , Karnitz Larry M.
Published: March 2023

PDF file - 117K, Supplementary Figure 1. MK-8776 and VE-821 sensitize PEO1 cells to chemotherapy agents.
Supplementary Table 5 from AC1MMYR2, an Inhibitor of Dicer-Mediated Biogenesis of Oncomir miR-21, Reverses Epithelial–Mesenchymal Transition and Suppresses Tumor Growth and Progression
Authors: Shi Zhendong , Zhang Junxia , Qian Xiaomin , Han Lei , Zhang Kailiang , Chen Luyue , Liu Jilong , Ren Yu , Yang Ming , Zhang Anling , Pu Peiyu , Kang Chunsheng
Published: March 2023

PDF file - 63K, KEGG pathway analysis indicated that there were 14 different pathways corresponding to the target genes.
Supplementary Table 4 from AC1MMYR2, an Inhibitor of Dicer-Mediated Biogenesis of Oncomir miR-21, Reverses Epithelial–Mesenchymal Transition and Suppresses Tumor Growth and Progression
Authors: Shi Zhendong , Zhang Junxia , Qian Xiaomin , Han Lei , Zhang Kailiang , Chen Luyue , Liu Jilong , Ren Yu , Yang Ming , Zhang Anling , Pu Peiyu , Kang Chunsheng
Published: March 2023

PDF file - 55K, Gene ontology analysis for the biologic processes associated target genes.
Supplementary Table 3 from Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Authors: Teitz Tal , Inoue Madoka , Valentine Marcus B. , Zhu Kejin , Rehg Jerold E. , Zhao Wei , Finkelstein David , Wang Yong-Dong , Johnson Melissa D. , Calabrese Christopher , Rubinstein Marcelo , Hakem Razqallah , Weiss William A. , Lahti Jill M.
Published: March 2023

XLSX file - 77K, Table S3- Data on the microRNAs that differ in expression between primary tumors Th- MYCN, Caspase-8 wild type levels with no BMM, and primary tumors Th-MYCN, deficient caspase-8 with BMM (p<0.05).
Supplementary Table 2 from AC1MMYR2, an Inhibitor of Dicer-Mediated Biogenesis of Oncomir miR-21, Reverses Epithelial–Mesenchymal Transition and Suppresses Tumor Growth and Progression
Authors: Shi Zhendong , Zhang Junxia , Qian Xiaomin , Han Lei , Zhang Kailiang , Chen Luyue , Liu Jilong , Ren Yu , Yang Ming , Zhang Anling , Pu Peiyu , Kang Chunsheng
Published: March 2023

XLSX file - 104K, The compounds were identified with high binding affinity after the docking process.
Supplementary Table 1 from Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Authors: Teitz Tal , Inoue Madoka , Valentine Marcus B. , Zhu Kejin , Rehg Jerold E. , Zhao Wei , Finkelstein David , Wang Yong-Dong , Johnson Melissa D. , Calabrese Christopher , Rubinstein Marcelo , Hakem Razqallah , Weiss William A. , Lahti Jill M.
Published: March 2023

XLSX file - 146K, Table S1- Data on the genes that differ in expression between primary tumors Th- MYCN, Caspase-8 wild type levels with no BMM, and primary tumors Th-MYCN, deficient caspase-8 with BMM (p<0.05).
Supplementary Figures 1 - 7 from Neuropilin-2 Is Upregulated in Lung Cancer Cells during TGF-β1–Induced Epithelial–Mesenchymal Transition
Authors: Nasarre Patrick , Gemmill Robert M. , Potiron Vincent A. , Roche Joëlle , Lu Xian , Barón Anna E. , Korch Christopher , Garrett-Mayer Elizabeth , Lagana Alessandro , Howe Philip H. , Drabkin Harry A.
Published: March 2023

PDF file - 1864K, NRP2 is stably up-regulated by TGFβ in lung cancer cells without increasing the halflife of mRNA or protein (S1); NRP2 up-regulation is blocked by inhibition of TβRI, AKT, ERK and ZEB1, but not by expression of inhibitory SMAD7 (S2); NRP2 knockdown blunts TGFβ-mediated transcriptional responses, ERK and AKT phosphorylation but does not influence SMAD activation (S3); NRP2 knockdown blocks cell scattering induced by TGFβ (S4); Immunohistochemical detection of NRP2 and cytokeratin in TGFβ exposed xenograft tumors with NRP2 or control knockdowns (S5); E-cadherin and NRP2 immunostaining of samples from a tumor microarray (S6); Predicted miRNA target sites in the 3' UTR of NRP2 and up-regulated NRP2 protein levels in hnRNP E1 knockdown cells (S7).
Supplementary Figure 2 from Critical Role of STAT3 in IL-6–Mediated Drug Resistance in Human Neuroblastoma
Authors: Ara Tasnim , Nakata Rie , Sheard Michael A. , Shimada Hiroyuki , Buettner Ralf , Groshen Susan G. , Ji Lingyun , Yu Hua , Jove Richard , Seeger Robert C. , DeClerck Yves A.
Published: March 2023

Supplementary Figure 2 - PDF file 179K, A, SK-N-SH cells were transfected with a STAT3 siRNA nucleotide or a scrambled sequence as described in Materials and Methods. After 72 hours, cells were treated with IL-6 (10 ng/mL) and sIL-6R (25 ng/mL) for 30 minutes and cell lysates were examined for expression of pSTAT3 and STAT3 by Western blot. The data are representative of 3 separate experiments. B, In parallel experiments, siRNA transfected CHLA-255 cells were treated with IL-6 and sIL-6R for 24 hours for Annexin V expression by flow cytometry. The data represent the mean (�SD) percentage of Annexin V positive cells of the control (treated with etoposide, 0.25 mg/mL) from three independent experiments. C, SK-N-SH cells were treated with IL-6 (10 ng/ml) at indicated time points and total cell lysates (20 �g) were obtained and examined for the expression of anti-apoptotic proteins by Western blot. Actin was used as loading control. The data are representative of 2 separate experiments showing similar results
Legends to supplementary figures from Critical Role of STAT3 in IL-6–Mediated Drug Resistance in Human Neuroblastoma
Authors: Ara Tasnim , Nakata Rie , Sheard Michael A. , Shimada Hiroyuki , Buettner Ralf , Groshen Susan G. , Ji Lingyun , Yu Hua , Jove Richard , Seeger Robert C. , DeClerck Yves A.
Published: March 2023

Legends to supplementary figures - PDF file 87K, Legends to supplementary figures 1 to 4
Supplementary Tables from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary tables PDF file 61K, Table I: Depiction of ALCAM immunoreactivity for HPA10926 which reacts with the extracellular domain and 1G3A1 which is specific for the intracellular domain. Table II: Comparison of High and Low ALCAM shedding colon cancer with respect to Age, Sex and Staging variables
Supplementary Movie 5 from Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Authors: Belaid Amine , Cerezo Michaël , Chargui Abderrahman , Corcelle–Termeau Elisabeth , Pedeutour Florence , Giuliano Sandy , Ilie Marius , Rubera Isabelle , Tauc Michel , Barale Sophie , Bertolotto Corinne , Brest Patrick , Vouret-Craviari Valérie , Klionsky Daniel J. , Carle Georges F. , Hofman Paul , Mograbi Baharia
Published: March 2023

AVI file - 5901K, Video 5 (related to Fig. 2G) is a time-lapse recording of a mononucleate a3-/- cell that formed a tetranucleate cell after two rounds of abortive mitosis.
Supplementary Figure Legends from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary Figure Legends PDF file 64K,Supplementary Figure Legends for Supplementary Figure 1-6
Supplementary Figure 6 from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary Figure 5 PDF file 1990K, Supplemental Figure 5: The image processing pipeline implemented using FIJI
Supplementary Figures 1 - 8 from Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Authors: Belaid Amine , Cerezo Michaël , Chargui Abderrahman , Corcelle–Termeau Elisabeth , Pedeutour Florence , Giuliano Sandy , Ilie Marius , Rubera Isabelle , Tauc Michel , Barale Sophie , Bertolotto Corinne , Brest Patrick , Vouret-Craviari Valérie , Klionsky Daniel J. , Carle Georges F. , Hofman Paul , Mograbi Baharia
Published: March 2023

PDF file - 3250K
Supplementary Table from KEAP1-Dependent Synthetic Lethality Induced by AKT and TXNRD1 Inhibitors in Lung Cancer
Authors: Dai Bingbing , Yoo Suk-Young , Bartholomeusz Geoffrey , Graham Ryan A. , Majidi Mourad , Yan Shaoyu , Meng Jieru , Ji Lin , Coombes Kevin , Minna John D. , Fang Bingliang , Roth Jack A.
Published: March 2023

PDF file, 70K, 3.Summary of synthetic lethality hits/genes.
Supplementary Figure 2 from Elevated ALCAM Shedding in Colorectal Cancer Correlates with Poor Patient Outcome
Authors: Hansen Amanda G. , Freeman Tanner J. , Arnold Shanna A. , Starchenko Alina , Jones-Paris Celestial R. , Gilger Michael A. , Washington Mary K. , Fan Kang-Hsien , Shyr Yu , Beauchamp Robert D. , Zijlstra Andries
Published: March 2023

Supplementary Figure 2 PDF 110K, Supplemental Figure 2: ALCAM expression in continuous cancer cell lines
Supplementary Table 1 from Quantitative In Vivo Characterization of Intracellular and Extracellular pH Profiles in Heterogeneous Tumors: A Novel Method Enabling Multiparametric pH Analysis
Authors: Lutz Norbert W. , Le Fur Yann , Chiche Johanna , Pouysségur Jacques , Cozzone Patrick J.
Published: March 2023

PDF file - 69K, Statistical parameters characterizing pHe heterogeneities modeled by phantoms.
Supplementary Figure 4 from Avirulent Toxoplasma gondii Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment
Authors: Baird Jason R. , Fox Barbara A. , Sanders Kiah L. , Lizotte Patrick H. , Cubillos-Ruiz Juan R. , Scarlett Uciane K. , Rutkowski Melanie R. , Conejo-Garcia Jose R. , Fiering Steven , Bzik David J.
Published: March 2023

PDF file - 167K, Supplementary Figure S4. Th17 cells do not play a significant role in the treatment by cps of ID8-Defb29/Vegf-A ovarian cancer model.
Supplementary Figure 3 from Avirulent Toxoplasma gondii Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment
Authors: Baird Jason R. , Fox Barbara A. , Sanders Kiah L. , Lizotte Patrick H. , Cubillos-Ruiz Juan R. , Scarlett Uciane K. , Rutkowski Melanie R. , Conejo-Garcia Jose R. , Fiering Steven , Bzik David J.
Published: March 2023

PDF file - 256K, Supplementary Figure S3. Gating strategy for figure 2.
Supplementary Methods from Membrane versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-Associated Myeloid Cells
Authors: Ardestani Shidrokh , Li Bin , Deskins Desirae L. , Wu Huiyun , Massion Pierre P. , Young Pampee P.
Published: March 2023

PDF file - 104K
Supplementary Figure 6 from Membrane versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-Associated Myeloid Cells
Authors: Ardestani Shidrokh , Li Bin , Deskins Desirae L. , Wu Huiyun , Massion Pierre P. , Young Pampee P.
Published: March 2023

PDF file - 100K, B16F10 Soluble factors derived from B16F10 mTNFα-expressing tumros do not affect the rate of CD11b+ myeloid cell migration compared to control.
Supplementary Figure 3 from Oncogenic Herpesvirus HHV-8 Promotes Androgen-Independent Prostate Cancer Growth
Authors: Mygatt Justin G. , Singhal Adit , Sukumar Gauthaman , Dalgard Clifton L. , Kaleeba Johnan A.R.
Published: March 2023

PDF file - 124K, Reactivation of HHV-8 from LNCaP-v219 cells relieves EZH2-mediated repression of DAB2IP and MSMB expression.
Supplementary Figure 2 from Membrane versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-Associated Myeloid Cells
Authors: Ardestani Shidrokh , Li Bin , Deskins Desirae L. , Wu Huiyun , Massion Pierre P. , Young Pampee P.
Published: March 2023

PDF file - 120K, In vivo growth of tumor cells transduced with various TNFα isoforms.
Supplementary Figure 1 from Membrane versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-Associated Myeloid Cells
Authors: Ardestani Shidrokh , Li Bin , Deskins Desirae L. , Wu Huiyun , Massion Pierre P. , Young Pampee P.
Published: March 2023

PDF file - 105K, Expression of mTNFα does not affect proliferation and viability in B16F10 melanoma cells.
Supplementary Table 6 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 152K, Correlation of GLI1 and MLH1 expression.
Supplementary Table 3 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 202K, BHLHE41 expression in pancreatic lesions.
Supplementary Table 1 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1
Authors: Inaguma Shingo , Riku Miho , Hashimoto Mitsuyoshi , Murakami Hideki , Saga Shinsuke , Ikeda Hiroshi , Kasai Kenji
Published: March 2023

PDF file - 963K, GLI1-ER regulated genes.
Supplementary Methods, Tables 1 - 4, Figures 1 - 2 from The Role of Cell Density and Intratumoral Heterogeneity in Multidrug Resistance
Authors: Lavi Orit , Greene James M. , Levy Doron , Gottesman Michael M.
Published: March 2023

PDF file - 2179K, Supplementary details on the mathematical model. Supplementary details concerning numerical results. Table S1. Range and biological interpretation of variables and parameters. Table S2. Simulation details of all variables and parameter values plotted in all figures. Table S3. Simulation details of Figure S2. Table S4. Dynamics with variations in the percentage of cells altered. Figure S1. Drug efficacy as a function of the dose and resistance level. Figure S2. Dynamics with variations in the mutation rates over time with/without drugs.
Supplementary Figure 3 from Autocrine Motility Factor Promotes HER2 Cleavage and Signaling in Breast Cancer Cells
Authors: Kho Dhong Hyo , Nangia-Makker Pratima , Balan Vitaly , Hogan Victor , Tait Larry , Wang Yi , Raz Avraham
Published: March 2023

PDF file - 660K, Supplementary Figure S3. Secretion and expression of AMF is positively correlated with p185- and p95-HER2.
Supplementary Table 5 from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 32K, Multivariate analysis of CRC survival and the polymorphisms TLR5 rs5744174, TIRAP rs611953 and rs625413 and MyD88 rs4988453.
Supplementary Table 2 from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 28K, Characteristics of the 613 CRC patients at the time of diagnosis.
Supplementary Figure 2 from An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
Authors: West Alison C. , Mattarollo Stephen R. , Shortt Jake , Cluse Leonie A. , Christiansen Ailsa J. , Smyth Mark J. , Johnstone Ricky W.
Published: March 2023

PDF file - 23K, Supplementary Figure 2. Rag-2γc-/- mice are not susceptible to drug-mediated toxicity and Eeta-myc cells do not develop resistance to vorinostat.
Supplementary Figures 1 - 6, Tables 1 - 3 from Transcription Poisoning by Topoisomerase I Is Controlled by Gene Length, Splice Sites, and miR-142-3p
Authors: Solier Stéphanie , Ryan Michael C. , Martin Scott E. , Varma Sudhir , Kohn Kurt W. , Liu Hongfang , Zeeberg Barry R. , Pommier Yves
Published: March 2023

PDF file - 2059K, Importance of Exon numbers for transcript downregulation by CPT (SF1); CPT up-regulates the p53 signaling pathway genes (SF2); Down-regulation of RNA degradation-related genes after CPT treatment (SF3); Down-regulation of ubiquitin-related genes after CPT treatment (SF4); Top1 down-regulation does not impacts gene expression for CUL5 and UBE2W (SF5); miR-142-3p decreases cell survival, and down-regulation of its target genes BCL2L1 and MAP3K7IP2 sensitize to CPT (SF6). *** List of Primers (ST1); List of the 3808 down-regulated genes in CPT-treated HCT116 cells, by 2-fold or more (ST2); List of the 835 up-regulated genes in CPT-treated HCT116 cells, by 2-fold or more (ST3).