bluuebunny/crossref_metadata_2025 huggingface dataset:
The Use of Email and Secure Messaging between Residents and Patients at St. Michael’s Family Medicine Residency Program
Authors: Javaid Sabahat , DeRocher MaryBeth
Published: November 2021

Background: The use of email and secure messaging between physicians and patients is increasing in frequency. P PHowever, residents lack formal training in e-communication, patient privacy and other confidentiality issues associated with it. There is also a paucity of assessment tools and faculty feedback regarding this practice.Objective: The objective is to investigate use of email and secure messaging between patients and residents at St. Michael’s family medicine residency program and analyze educational constructs, facilitators, and barriers relevant to this practice.Methods: Three cross-sectional surveys were conducted at St. Michael’s family medicine residency program in 2018-2020. Each resident in postgraduate year 1 & 2 received an email inviting them to respond.

Results: The prevalence of residents using email or secure messaging is increasing (47% in 2018 vs 81% in 2020). Over 86% of FM residents used hospital/clinic computers in 2020 but the proportion of residents using personal computers rose to 60% that year. A prominent barrier appears to be the ‘potential for inappropriate use by patients’, which was cited as ‘fairly’ or ‘very’ important at rates of 85.3%, 86.9%, and 73.68% in 2018, 2019 and 2020, respectively. 76.4% and 56.52% of residents cited lack of consistent advice/guidelines as a barrier in the years 2018 and 2019, respectively. The perception of support has risen (33.3% residents reporting supervisors as ‘very’ or ‘somewhat’ supportive versus 57.8% in 2020). The majority reported ‘rarely’ or ‘never’ getting feedback/guidance from their supervisors.Conclusions: Our study found an increase in the use of email and secure messaging. Residents are increasingly using their personal computers which likely reflects the increase in virtual models of care. Residents have concerns regarding the appropriate use of such messaging by patients. Lack of supervision may pose a risk of patient confidentiality/privacy breach. There is a need for curricular re-design and faculty development around this practice.
Análisis de la huella de carbono en vías de pavimento flexible (asfalto): Vías de segundo orden en la provincia del Azuay
Authors: Beltrán Castro Pablo Esteban , García Molina Karla Belén , Cordero Cabrera Carlos Julio
Published: November 2021

Objetivo. Determinar los mayores contaminantes generados durante la etapa de construcción y mantenimiento del proyecto vial Minas- Tablón - Pucará. Metodología. Se analizó 1 Km de vía y se estableció todos los factores que se generan por las actividades durante todas las fases del proyecto, mediante el software SimaPro 9.1.1.1 y la metodología de ReCiPe Midpoint se distinguió diferentes fases como definición del enfoque y límites del sistema, inventario, análisis del impacto y la interpretación de los resultados, con lineamientos de las normas ISO 14040 y 14044, se identificó y evaluó los impactos ambientales durante todas las etapas del ciclo de vida. Además, mediante el sistema de información geográfica ARC-GIS, los shape del Ministerio de Agricultura y Ganadería MAG 25k 2018 y los puntos de georreferencia tomados en campo se determinó la cobertura y uso de suelo que corresponde a la zona donde se ubica el proyecto. Resultados. Entre los resultados que mayor contaminación presentan se encuentra la etapa de mantenimiento, esta genera un alto índice de cambio climático (67.1%), agotamiento fósil (68%), material particulado (94.1%) y toxicidad humana (90.2%). Conclusión. Durante la etapa de mantenimiento las intervenciones humanas son más periódicas por lo que se generan mayor contaminación, además, la vía de estudio es de asfalto por lo que se presenta mayores químicos y compuestos, incluso a lo que refiere a la metodología constructiva genera incremento de emisiones que aporta considerablemente al calentamiento global y cambio climático.
Prevention of Insurance’ Criminal Offenses in Ukraine
Authors: Tychyna Dmytro , Sobkovych O.
Published: November 2021

The purpose of this article is to study the most common criminal offenses in the field of insurance in Ukraine and identify effective measures to prevent criminal offenses of this category, in order to implement them into the legal reality of Ukraine. Methodology. Methodological tools are selected in accordance with the purpose, specifics of the object and subject of research. In the course of the research the generalization, processing and analysis of the obtained results were carried out. A special research method used in the article is the method of systems analysis. The scientific novelty of the publication is that based on the analysis of quantitative and qualitative characteristics of criminal offenses in the field of insurance, the system of criminally punishable acts that encroach on various objects of criminal law protection is determined. A special place in it is occupied by various types of illegal seizure of the insurance company's property by professional insurance market participants and policyholders. Conclusions. Given the scale of criminal offenses in the field of insurance, insurance companies need to work together to avoid them. This requires the creation of associations, tandems of insurers, in which to combine databases containing information about the insured, “blacklists” of unscrupulous policyholders, joint regional data banks on potential fraudsters and other information. In addition, the priority of crime prevention in this segment is the interaction of law enforcement agencies with the security services of insurance companies in detecting fraud and other illegal acts aimed at illegally obtaining insurance compensation. We believe that the practical application of the above measures will contribute to the development of the domestic insurance market and increase the efficiency of the insurance institution in general
El contrato administrativo electrónico
Authors: López-López Freddy
Published: November 2021

El contrato administrativo electrónico como parte de las actividades que se desarrolla dentro del derecho público, reviste de gran importancia a raíz de la sistematización de las formas o procedimientos de la contratación pública, que se han complementado en la necesidad de la utilización de herramientas tecnológicas integradas por un sistema oficial de la contratación pública en donde todo proceso, procedimiento concerniente a esta materia contractual se genere de acuerdo a estos sistemas y forme parte de una regulación normativa, de cumplimiento obligatorio por las administraciones públicas y sus concursantes que se rigen sobre la aplicación de criterios constitucionales y de varios principios contractuales.El desarrollo de las aplicaciones informáticas y telemáticas a nivel estatal hace posible que exista la necesidad de la automatización de la actividad administrativa, así como también el de contratar electrónicamente.
Аналіз функціонування системи відновлення озброєння та військової техніки
Authors: Ovcharenko Igor , Zvonko Andrey , Tkachenko Anton , Yaroshenko Alexander
Published: November 2021

Особливості ведення війн та збройних конфліктів вказують на те, що для забезпечення живучості військових формувань, які приймають участь в операціях (бойових діях), одним із пріоритетів є своєчасне повернення до строю пошкоджених зразків озброєння та військової техніки. Успіх виконання завдань під час ведення збройного протистояння в значній мірі буде залежати не тільки від вогневих і ударних можливостей угруповань військ (сил), але і від того, як швидко вони зможуть відновити свою боєздатність в умовах впливу сучасних засобів ураження. Завдання щодо своєчасного відновлення озброєння та військової техніки, в ході ведення операцій (бойових дій) покладається на ремонтно-відновлювальні органи від яких залежить рівень укомплектованості військ (сил) справними зразками озброєння та військової техніки.

В статті проведено аналіз умов та факторів, які впливали на систему відновлення озброєння та військової техніки в широкомасштабних операціях у Другій Світовій Війні та в локальних війнах в Афганістані, в операції російських військ в Першій Чеченській кампанії. Розкриті основні проблеми з якими стикались ремонтно-відновлювальні підрозділи та частини під час відновлення озброєння та військової техніки в цих війнах та локальних збройних конфліктах з метою визначення характерних проблемних питань, що призводять до зниження рівня боєздатності військ.
Рекомендації начальнику відділу прикордонної служби під час організації спеціальних дій щодо пошуку правопорушників
Authors: Torichnyi Vadym , Raiko Valerii , Zaharchuk Denys , Andrushko Volodymyr
Published: November 2021

У статті на підставі сучасних підходів модернізації охорони державного кордону и прикордонной практики проведено аналіз керівних документов, по регламенту організацію оперативно-службово діяльності відділу прикордонної службы. Визначено порядок організації и проведение специальных операций по отправке правопорушников відділом прикордонной служби. Установлено, по данным периодов немаловажных практичных рекомендаций начальника отдела прикладных служб, порядковых органов и руководителей специальных служб.

В умовах динамического розвитку обстановки на державном кордоні виникають обставины, які потребують оперативного реагування и кратної реалізації заходы щодо запобігання протиправній діяльності, а саме пошуу и затримання правопорушору. Практика определения значений заходов на ділянці відповідальності відділів прикордонної службы в багатьох випадках свідчить про залежність успіху протидії протиправній діяльність від завчасної спецізації. Разом с этим, новые возможности исправления у здоровых производственных помещений и спроектированы в соответствии с международными службами в проведенных спецслужбах.

Пошук наукових шляхів вирішення цього протиріччя і визначає потребу більш ґрунтовного анализа даної проблеми. Актуальність статті полягає у дослідженні напрацьованая практичный досвід застосуваннь в органах охорони державного кордона Державної прикордонної службі України сил тех засобов відділа прикордонної службите при проведені спеціальнего дого щодо пошука правопорушников, усунення протиріч, які виникають в процесі завчасної підготовка, організації та ведення спеціальний дій по пошуку правопорушники відділом прикордонної служби.
Підвищення рухомості транспортних агрегатів засобів технічного забезпечення мобільного комплексу озброєння як перспективний шлях зменшення імовірності їх ураження
Authors: Levagin Gennady , Mishukov Alexander , Lytovchenko Dmytro , Riazantsev Serhii , Hulenov Ivan
Published: November 2021

Запропоновано підхід щодо зменшення імовірності ураження засобів технічного забезпечення мобільного комплексу озброєння в умовах ведення бойових дій шляхом підвищення їх рухомості. Введено новий показник, що дозволяє оцінити технічну досконалість технологічного устаткування транспортного агрегату засобу технічного забезпечення.
Розробка математичних моделей розрахунку матеріальних резервів техніки сил цивільного захисту
Authors: Divizinyuk Mykhailo , Yelisieiev Valeriy , Mirnenko Volodymyr , Pruskyi Andrii , Tishchenko Vasyl , Vlasenko Evgene
Published: November 2021

Розроблено математичні моделі розрахунку різних видів матеріального резерву техніки (об’єктів озброєння) сил цивільного захисту для забезпечення оперативного реагування на надзвичайні ситуації техногенного, природного, соціального та воєнного характеру. Новий науковий результат полягає в низці математичних моделей, що створені для підвищення ефективності функціонування техніки, підрозділів сил цивільного захисту при виконанні завдань з ліквідації наслідків надзвичайних ситуацій, а також в цілому ефективності функціонування єдиної державної системи цивільного захисту. Показано, що для забезпечення ефективного функціонування підрозділів сил цивільного захисту при виконанні завдань з ліквідації надзвичайних ситуацій та їх наслідків на достатньому (заданому) рівні готовності з урахуванням наявності різних видів матеріальних резервів необхідно розробити моделі які б дозволяли визначити необхідні види та обсяги матеріальних резервів. Запропоновано та введено до розгляду поняття декількох видів матеріальних резервів, необхідних для забезпечення експлуатації та ремонту техніки та озброєння. Матеріальні резерви можуть утворюватися за окремими типами елементів на складах – складський, комплект матеріального резерву для окремого типу техніки чи озброєння на один об’єкт – об’єктовий або на групу однотипних об’єктів техніки – груповий. Складовими моделей розрахунку різних видів матеріальних резервів, що розглядається, є можливість раціонального визначення об’єму складського матеріального резерву для забезпечення запобігання та ліквідації надзвичайних ситуацій та їх наслідків на достатньому рівні, раціонального визначення рівня одиночного матеріального резерву на достатньому рівні при мінімальній вартості, а також матеріального резерву групи однотипних об’єктів озброєння при заданому коефіцієнті забезпеченості при мінімальної вартості. Для оцінки впливу матеріальних резервів на ефективність функціонування підрозділів сил цивільного захисту  при ліквідації НС та їх наслідків використано деякі показники надійності озброєння визначені у державному стандарті ДСТУ 2860-94. Надійність техніки. Терміни та визначення. В роботі приведено алгоритм дій при розрахунку різних видів матеріального резерву об’єктів озброєння сил цивільного захисту.
Desafios e paradigmas para o exercício da preceptoria frente ao feedback formativo em residências de Enfermagem
Authors: Sales Junior Carlos Antonio Farias , Ferreira Ilma Pastana , Sacramento Ruhan da Conceição , Moura Marcella Lacerda , Palacios Vera Regina da Cunha Menezes , Portella Márcia Bitar , Barros Larissa Cristina Machado de
Published: November 2021

Objetivo: identificar, por meio da busca na literatura, as evidências que cerceiam a importância do feedback, bem como os desafios e paradigmas para o exercício da preceptoria e do feedback formativo no contexto das residências em enfermagem. Método: Pesquisa de abordagem qualitativa, com natureza descritiva, da tipologia Revisão Integrativa da Literatura. A coleta de dados ocorreu a partir dos seguintes critérios de inclusão: Textos com resumos e disponíveis de forma completa online; artigos nos idiomas português e inglês; estudos publicados de 2016 a 2021. A questão que norteou a busca foi: “Quais as evidências nas bases de dados sobre o exercício da preceptoria frente ao feedback formativo em residências de enfermagem?”. As bases de dados utilizadas foram Literatura Latino-Americana e do Caribe em Ciências da Saúde e Medical Literature Analysis and Retrieval System Online e BDENF – Enfermagem, por meio do Portal da Biblioteca Virtual em Saúde com os Descritores – descritores controlados – Feedback formativo; Enfermagem; Internato não médico; Preceptoria; Educação em Enfermagem; Educação de pós-graduação em enfermagem; e com as palavras-chave – descritores não controlados: Pós-graduação; Feedback e Preceptor. Resultados: Foram selecionados 7 artigos, os quais foram analisados e originaram 3 categorias. 1) A importância do Feedback Formativo na formação em residências; 2) O papel do preceptor Enfermeiro perante os residentes e ao Feedback Formativo e 3) Entraves para a atuação na preceptoria em residências e o processo de Feedback Formativo. Considerações Finais: A partir dessa revisão de literatura, foi possível identificar a importância do feedback formativo, bem como da preceptoria na ambiência das residências de enfermagem.
World Café technique as a pedagogical action in nursing education to address the reception of trans people in health care
Authors: Duarte Douglas Dias , Queluci Gisella de Carvalho
Published: November 2021

A atenção à saúde da mulher trans e do homem trans possuem muitos desdobramentos com relação as suas especificidades, logo se faz necessário que a construção desse conhecimento ocorra na graduação do profissional enfermeiro com objetivo de analisar, sob a luz da Metodologia de Resolução de Situações-Problema a eficácia da técnica do world café, para a construção de conhecimento dos estudantes de enfermagem diante da resolutividade de problemas acerca da assistência à pessoas transexuais, travestir e transgênero a partir de uma oficina pedagógica. Método: Pesquisa de abordagem qualitativa, de característica: estudo de campo, exploratório e temático realizada em fevereiro de 2020, através de uma oficina no modelo de World café que é uma técnica de geração de ideias de forma colaborativa. Os resultados apresentados aqui fazem parte de um recorte da dissertação para o curso de Mestrado. Os dados foram analisados seguindo os pressupostos de análise do discurso proposto por Laurence Bardin e seus resultados foram agrupados por categorias de análise: I – Educação em saúde; II- Competências; III - Ética profissional. A pesquisa demonstra a importância da construção do saber acerca do cuidado a saúde das pessoas Trans, ainda no curso de graduação e de pesquisas, a fim de, promover a atenção a saúde de qualidade, integralidade, igualdade e equidade de homens e mulheres trans.
Incidência de Fusarium spp. em milho: da planta ao grão
Authors: Calegari Bruno Henrique , Souza Ícaro Pereira de , Ruffato Solenir , Bonaldo Solange Maria , Prado Priscylla Martins Carrijo
Published: November 2021

É difícil de ser estabelecido o momento em que os fungos fitopatogênicos afetam os grãos quando ainda no campo, sendo Fusarium um dos principais fungos da cultura do milho que causa perda de produtividade e qualidade dos grãos produzidos. Assim objetivou-se com este estudo quantificar a incidência de Fusarium spp. na cultura do milho em função dos estádios fenológicos, em diferentes híbridos e épocas de plantio. Avaliou-se a indicidência do fungo nas folhas, pendões e espigas, pelo método de isolamento indireto de fungos fitopatogênicos. As coletas dos materiais foram realizadas nos estádios V7, VT, R1, R3, R4, R6 e pré-colheita, nas épocas de plantio Dezembro à Março (1ª safra) e Março à Junho (2ª safra). Os híbridos avaliados na 1ª safra foram ADV 9275 PRO e SEMPRE 20A30 e na 2ª safra, RB9110PRO2, 2B512PW, 2B633PW e 2A401PW. Os híbridos apresentaram a mesma tendência de incidência de Fusarium spp. nas folhas e pendões em ambas as safras. Os estádios reprodutivos demostraram elevada incidência de Fusarium spp. em todas as partes da planta avaliadas, sendo que nos estádios R6 e pré-colheita observou-se as maiores incidências fúngicas, independente do híbrido e época de plantio. Os híbridos SEMPRE 20A30, 2A401 PW e 2B512 PW obtiveram maior incidência de Fusarium spp., enquanto que o material RB9110 PRO2 apresentou maior resistência ao fungo. Na 1ª safra os híbridos apresentaram maior incidência do fitopatógeno na espiga, enquanto que na 2ª safra houve maior incidência na folha e no pendão.
Compostos de biopolietileno/línter de algodão compatibilizados com PE-g-MA
Authors: Salviano Aline Florindo , Luna Carlos Bruno Barreto , Siqueira Danilo Diniz , Araújo Edcleide Maria , Ferreira Rodholfo da Silva Barbosa , Bezerra Elieber Barros
Published: November 2021

Atualmente, os polímeros vêm sendo reforçados com fibras naturais, visando a geração de uma classe de novos materiais menos agressivos ao meio ambiente. Portanto, este trabalho teve como objetivo desenvolver compostos de biopolietileno (BioPE)/línter de algodão, compatibilizados com o polietileno enxertado com anidrido maleico (PE-g-MA). Os compostos foram preparados, inicialmente, em uma extrusora de rosca dupla corrotacional e, posteriormente, os grânulos extrudados foram moldados por injeção. As propriedades mecânicas (impacto e tração), temperatura de deflexão térmica (HDT), temperatura de amolecimento Vicat (TAV), calorimetria exploratória diferencial (DSC), ângulo de contato e microscopia eletrônica de varredura (MEV) foram avaliadas. Observou-se um aumento discreto no módulo elástico, na resistência à tração, na HDT e na TAV dos compostos, em relação ao BioPE puro. Todavia, houve perdas na resistência ao impacto. A presença do PE-g-MA e do línter aumentou o grau de cristalinidade dos compostos, em comparação ao BioPE. Os compostos compatibilizados apresentaram partículas de línter conectadas com a matriz de BioPE, indicando possíveis interações entre o anidrido maleico e os grupos hidroxilas do línter. Resultados aprimorados foram alcançados quando se utilizou PE-g-MA com maior grau de enxertia, sugerindo que a funcionalização impacta nas propriedades mecânicas e térmicas dos compostos.
Necessidades energéticas e consumo alimentar de adolescentes do interior baiano
Authors: Assunção Tailane dos Santos , Barroso Rosemary da Rocha Fonseca , Fideles Ingrid Cardoso , Aquino Rosana
Published: November 2021

Com o objetivo de contribuir com uma abordagem metodológica, este estudo comparou as necessidades energéticas, obtidas por meio de equações preditivas, com os dados de consumo alimentar de uma população de adolescentes escolares, de municípios baianos, e ainda, conhecer o espaço alimentar e as refeições realizadas por essa população. Trata-se de um estudo transversal, aninhado a um ensaio comunitário randomizado controlado, realizado com estudantes do ensino médio de escolas públicas de dez municípios baianos. O consumo alimentar foi obtido por meio de questionário de frequência alimentar quantitativo e de três registros alimentares. Utilizaram-se as Dietary Reference Intakes e Schofield para o cálculo das necessidades nutricionais. Dados antropométricos (peso, altura, circunferência da cintura), sociodemográficos e de atividade física foram analisados de forma descritiva e associações testadas usando o teste do qui-quadrado e teste exato de Fischer, com nível de significância de 0,95. A amostra foi composta por 85 adolescentes, eutróficos (83,1%), ativos (69,5%), e a maioria das refeições principais (café da manhã, almoço e jantar) sendo realizadas no domicílio (>80%). As diferenças entre as necessidades nutricionais recomendadas e o consumo alimentar, foram estatisticamente significativas (p<0,05) e sinalizam a necessidade da acurácia na investigação de desfechos relacionados à alimentação e gasto energético em adolescentes. A avaliação das necessidades nutricionais para grupos populacionais é de importância no âmbito da Saúde Pública, bem como, conhecer a situação alimentar e nutricional preponderante em todas as faixas etárias, especialmente nos estágios de vida críticos para a formação de novos hábitos, como a adolescência.
Estudo da qualidade do agregado miúdo utilizado na construção civil
Authors: Sousa Rebeka Manuela Lobo , Silva Paulysendra Felipe , Oliveira Francisca das Chagas , Sousa Heitor Fernandes , Lopes Phillype Dowglas , Chaves Francisco Arlon de Oliveira , Falcão Milton de Sousa , Paz Gilvan Moreira da , Soares Roberto Arruda Lima
Published: November 2021

O agregado miúdo na sua composição natural pode apresentar diversas propriedades que podem ser alteradas em virtude do tipo e quantidade dos componentes envolvidos. Para identificar tais propriedades é necessário que seja feito experimentos utilizando métodos e equipamentos específicos. Diante deste contexto, este trabalho tem a finalidade de fazer, analise nas amostras de jazidas de agregados miúdos para verificar a qualidade deste material. O estudo terá como ponto de partida ensaios para a definição granulométrica, florescência de raio X (FRX) e difração de reio X (DRX). Após a execução dos ensaios laboratoriais, serão montadas as respectivas tabelas dos resultados da granulometria e FRX, um gráfico com resultados do ensaio de DRX e das curvas granulométricas para cada amostra. Com base nos resultados experimentais obtidos de acordo com as normas vigentes, serão efetuadas as análises. Na conclusão deste artigo pretende-se definir a qualidade dos três tipos de agregados miúdos é a mais adequada para cada especialidade na construção civil.
Perfil de sono e tempo de estudo em acadêmicos do internato de Medicina
Authors: Santos Agnes Suelen Paiz dos , Dall’Agnol Letícia Decezaro , Lutinski Junir Antonio
Published: November 2021

O sono participa de inúmeras funções fisiológicas e é o responsável pela manutenção da saúde física e psicológica. Porém, o que se observa nos acadêmicos de Medicina durante o período de internato, é uma carga horária muito extensa que contempla aulas e estágio, fazendo com que a escolha entre qualidade de sono e o bom desempenho acadêmico seja uma necessidade. Este estudo teve como objetivos caracterizar a qualidade do sono de acadêmicos do internato de Medicina e avaliar o impacto do sono na rotina dos acadêmicos de Medicina do quinto e do sexto ano do curso. Os dados para a realização do trabalho foram coletados por meio de um formulário online aplicado aos estudantes do internato no mês de março de 2021. A análise foi feita por meio da interpretação da coleta de dados dispostos em uma planilha no sistema Microsoft Office Excel 2016 e no software Past 4.05. Participaram do estudo 36 alunos, dentre os quais 69,4% foram mulheres e 30,6% são homens. Observou-se, que a quantidade média de horas dormidas pelos estudantes foi de 6,03 (DP±0,84), sendo inferior ao recomendado, e a qualidade do estudo é maior quando os acadêmicos têm mais horas de sono, demostrando assim o impacto do sono no bom desempenho acadêmico, fazendo com que sejam necessárias menos horas de estudo para consolidar o conteúdo de forma efetiva.
“The dwarf, the fool, the eunuch are all his”: Venice, Carnival, Reproduction and Plague in Volpone
Authors: Thiele Matthew
Published: November 2021

This essay explores the significance of setting Volpone (1606) in Venice while England was recovering from a major plague epidemic in 1603. The play directly references Venice's long history with the plague as a way of indirectly referencing England's struggle with plague in and around the time of the play's production. Doing so enables the play to address from a safer distance uncomfortable realities about plague time in a way that benefits Ben Jonson's English audience. The play alludes to plague through its references to plague-time beliefs and practices such as omens, medicine, and quarantine, and associating several characters with carrion birds would have been an unmistakable reference to plague for Jonson's audience. The theme of reproduction anxiety that runs throughout the play is also a recognizable characteristic of plague literature. Volpone's association with disease, carrion birds, monstrous births, and other plague omens and signs allows the anxiety produced by these elements to be purged at the end of the play when Volpone is cast out.
Matter and Sense in Gilles Deleuze’sLogic of Sense: Against the ‘Ism’ in Speculative Realism
Authors: Williams James
Published: November 2021

I argue against the use of general ‘ism’ terms such as ‘speculative realism’ and ‘correlationism’ by Harman. This use is contrasted with more nuanced readings of philosophers, referring to Bryant and DeLanda’s more subtle versions of materialism that do not fit the general label. Instead of general categories I defend Deleuze’s use of the concept of problem as studied by Bell. This argument is then developed through a close reading of Logic of Sense, against Harman’s denial of the reality of relations and processes. I demonstrate that Deleuze is not a correlationist as defined by Harman, by following Sauvagnargues, Smith and Beistegui on the concepts of event and simulacrum in Logic of Sense. I then consider Deleuze’s study of language and his argument that designation, signification and manifestation rely on the concept of sense. This argument leads to a position which is neither idealism, nor materialism, because the differential processes at work in sense cannot be reduced to matter or to the subject, working instead between them and denying their independent reality.
A Politics of Things? Deleuze and the New Materialism
Authors: Schleusener Simon
Published: November 2021

Concentrating on the way in which new materialist authors like Jane Bennett have read and appropriated the philosophy of Gilles Deleuze, this essay has two major objectives: first, it aims to point out the shortcomings of the new materialism's concept of the political (as it is formulated in Bennett's Vibrant Matter). Second, it seeks to investigate the differences and affinities between neomaterialist thought and Deleuze's philosophy. While Deleuze's focus on material becomings and concrete assemblages certainly lends itself to being utilised by neomaterialist authors, what many of these authors tend to ignore is the Marxian influence in Deleuze's thinking. It would be misleading, then, to see Deleuze as a new materialist avant la lettre, thereby implying that he categorically dismissed the ‘old’ (i.e. historical) materialism. Rather, what is unique about Deleuze's philosophy is its combination of a Marxist understanding of modes of production and their material conditions with a social ontology – inspired, among others, by Spinoza and Tarde – that emphasises the complex intermingling of human and non-human actors.
Memorization in DSS, NT, Talmud and Patristic Documents
Authors: Chia Philip Suciadi , Juanda Juanda
Published: November 2021

The history of civilization has its own uniqueness. There is an era in which all forms of knowledge must be memorized. However, after the advent of the printing press, many books circulated that could be a source of knowledge. And after this post-modern era arrives, all knowledge is available at hand via smart-phone at any time.According to historical records, education in the Jewish tradition is very strict. From an early age, a human child has been accustomed to remember what has been learned as part of life. There are four records in history to understand the practice of learning in understanding God's Law carefully and memorizing it. These sources from different eras testify simultaneously that memorization is a must for Jewish education context both at home, public school and synagogue. The sectarian, in Qumran, maintained their own strict interpretation of the Law. Family was still the chief institution and primary context for the dispensation of elementary instruction; although the scribes, Pharisees and learned rabbis played a major role in Jewish education during the NT era. Talmud is more specific about the age of studying and the sign of mastering. Origen also was trained since his childhood by his father, Leonides, to memorize Scripture daily and recite them every day.
Double Predestination View By John Calvin, In His Commentaries And Institutio Book
Authors: Sulastri Elisabeth
Published: November 2021

This article discusses the teaching view of John Calvin about Double Predestination. Any Bible verses that are the basis of explaining this teaching. The explanation of these verses can be the basis for understanding the teaching of John Calvin about Double Predestination. There are three topic discussions in this article, First Double Predestination View by John Calvin, second in His Commentaries, and third institution book. May this article provide new insight and enlightenment for every reader.
State Support for Shared Research Facilities: Any Results Yet?
Authors: Kalyuzhnyi Kirill
Published: November 2021

Introduction. The article is based on the findings collected by monitoring the Russian Сore Shared Research Facilities (CSRF) and Large-Scale Research Facilities (LSRF). The monitoring is carried out annually by RIEPL specialists on behalf of the Ministry of Education and Science of Russia. The author suggests that the CSRFs and LSRFs sponsored by the state under the federal target programme Research and Development in Priority Areas of Development in Science and Technology in Russia for 2014-2021 stand to deliver high performance across the key indicators, namely the number of external users, value of the work performed for their benefit, and actual workload on research equipment in the interests of external users. Monitoring Tools. The empirical basis of the study is the reporting data for 2014-2020, obtained from CSRFs and LSRFs representatives through the use of the web forms on the portal http://ckp-rf.ru. Results. In the group of sponsored CSRFs, the high growth rate in the number of external users and the average value of the work completed was due to the expansion of the range of services through the use of equipment purchased under the Federal Target Programme. The growth rate of the actual workload proved to be lower compared to the other groups. In the group of sponsored LSRFs, only the actual workload values showed some growth. The growth rate in the number of external users was lower compared to the non-sponsored facility group; the growth rate in the value of work performed did not change from the 2014 baseline. It is, therefore, concluded that there is a need to abandon the competitive financing of shared use infrastructure in favour of targeted financing. Conclusion. The results may be useful in assessing the state of the Russian research infrastructure and divising guidelines for its continued support.
Key Role of Staphylococcal Fibronectin-Binding Proteins During the Initial Stage of Staphylococcus aureus Keratitis in Humans
Authors: Maurin Corantin , Courrier Emilie , He Zhiguo , Rigaill Josselin , Josse Jérôme , Laurent Frédéric , Gain Philippe , Thuret Gilles , Verhoeven Paul O.
Published: November 2021

Objectives

Staphylococcus aureus is one of the main causes of bacterial keratitis in humans. This study was aimed at investigating the mechanisms of S. aureus adhesion to the human corneal epithelium involved during the initial stage of infectious keratitis.

Methods

Human corneas stored in a specific active storage machine that restores a normal pluristratified epithelium were used to assess S. aureus adhesion level to intact and injured tissues using immunostaining. S. aureus adhesion to immobilized fibronectin was measured in microtiter plate. Internalization of S. aureus clinical isolates recovered from keratitis was assessed on human corneal epithelial HCE-2 cells.

Results

Superficial corneal injury unmasked fibronectin molecules expressed within the human corneal epithelium. S. aureus adhesion level was increased by 117-fold in the area of injured epithelium (p < 0.0001). The deletion of staphylococcal fnbA/B genes decreased by 71% the adhesion level to immobilized fibronectin (p < 0.001). The deletion of fnbA/B genes and the incubation of the corneas with anti-fibronectin blocking antibodies prior to the infection significantly reduced the S. aureus adhesion level to injured corneal epithelium (p < 0.001). Finally, S. aureus clinical isolates triggered its internalization in human corneal epithelial cells as efficiently as the 8325-4 wt.

Conclusion

S. aureus was almost unable to bind the intact corneal epithelium, whereas a superficial epithelial injury of the corneal epithelium strongly increased S. aureus adhesion, which is mainly driven by the interaction between staphylococcal fibronectin-binding proteins and unmasked fibronectin molecules located underneath the most superficial layer of the corneal epithelium.
The Function of cGAS-STING Pathway in Treatment of Pancreatic Cancer
Authors: Mohseni Ghazal , Li Juan , Ariston Gabriel Abakundana Nsenga , Du Lutao , Wang Yun-shan , Wang Chuanxin
Published: November 2021

The activation of stimulator of interferon genes (STING) signalling pathway has been suggested to promote the immune responses against malignancy. STING is activated in response to the detection of cytosolic DNA and can induce type I interferons and link innate immunity with the adaptive immune system. Due to accretive evidence demonstrating that the STING pathway regulates the immune cells of the tumor microenvironment (TME), STING as a cancer biotherapy has attracted considerable attention. Pancreatic cancer, with a highly immunosuppressive TME, remains fatal cancer. STING has been applied to the treatment of pancreatic cancer through distinct strategies. This review reveals the role of STING signalling on pancreatic tumors and other diseases related to the pancreas. We then discuss new advances of STING in either monotherapy or combination methods for pancreatic cancer immunotherapy.
ATP and Tri-Polyphosphate (TPP) Suppress Protein Aggregate Growth by a Supercharging Mechanism
Authors: Bye Jordan , Murray Kiah , Curtis Robin
Published: November 2021

A common strategy to increase aggregation resistance is through rational mutagenesis to supercharge proteins, which leads to high colloidal stability, but often has the undesirable effect of lowering conformational stability. We show this trade-off can be overcome by using small multivalent polyphosphate ions, adenosine triphosphate (ATP) and tripolyphosphate (TPP) as excipients. These ions are equally effective at suppressing aggregation of ovalbumin and bovine serum albumin (BSA) upon thermal stress as monitored by dynamic and static light scattering. Monomer loss kinetic studies, combined with measurements of native state protein–protein interactions and ζ-potentials, indicate the ions reduce aggregate growth by increasing the protein colloidal stability through binding and overcharging the protein. Out of three additional proteins studied, ribonuclease A (RNaseA), α-chymotrypsinogen (α-Cgn), and lysozyme, we only observed a reduction in aggregate growth for RNaseA, although overcharging by the poly-phosphate ions still occurs for lysozyme and α-Cgn. Because the salts do not alter protein conformational stability, using them as excipients could be a promising strategy for stabilizing biopharmaceuticals once the protein structural factors that determine whether multivalent ion binding will increase colloidal stability are better elucidated. Our findings also have biological implications. Recently, it has been proposed that ATP also plays an important role in maintaining intracellular biological condensates and preventing protein aggregation in densely packed cellular environments. We expect electrostatic interactions are a significant factor in determining the stabilizing ability of ATP towards maintaining proteins in non-dispersed states in vivo.
Microencapsulated Phase Changing Materials for Gypsum Plasters: A Practical Approach
Authors: Claude Vincent , Charron Stéphane , de Barquin Fabrice , Dirkx Inge
Published: November 2021

Several studies have shown the feasibility and thermal potential of gypsum plaster with microspheres of PCM, but very few of them investigated an approach with practical and standards concern. In this work, different characterizations are performed according to European standards on a standard gypsum plaster and two different gypsum plasters formulated with 20 wt.% of PCM microspheres. A material is experimentally made by mixing conventional gypsum and PCM microspheres, whereas the other is an already prepared commercial mix. For the laboratory material, the addition of PCM increases the consistency of the fresh paste of plaster. In order to reach a consistency in agreement with the standards more water is required. This higher amount of water causes further issues on the densification and cohesion properties. In contrary, the properties of the commercial mix are closer to a common plaster. It is therefore assumed that the commercial material incorporates thinner additives. In view of these results, it is assumed that most of the drawbacks due to the addition of PCM microspheres in gypsum plasters could effectively be encountered by adequate addition of additives in order to reduce the amount of water, and binding resins in order to improve the adhesion and mechanical properties.
Diamond and Other Exotic Mineral-Bearing Ophiolites on the Globe: A Key to Understand the Discovery of New Minerals and Formation of Ophiolitic Podiform Chromitite
Authors: Liu Fei , Lian Dongyang , Wu Weiwei , Yang Jingsui
Published: November 2021

Ophiolite-hosted diamond from peridotites and podiform chromitites significantly differs from those of kimberlitic diamond and ultra-high pressure (UHP) metamorphic diamond in terms of occurrence, mineral inclusion, as well as carbon and nitrogen isotopic composition. In this review, we briefly summarize the global distribution of twenty-five diamond-bearing ophiolites in different suture zones and outline the bulk-rock compositions, mineral and particular Re-Os isotopic systematics of these ophiolitic chromitites and host peridotites. These data indicate that the subcontinental lithospheric mantle is likely involved in the formation of podiform chromitite. We also provide an overview of the UHP textures and unusual mineral assemblages, including diamonds, other UHP minerals (e.g., moissanite, coesite) and crustal minerals, which robustly offer evidence of crustal recycling in the deep mantle along the suprasubduction zone (SSZ) and then being transported to shallow mantle depths by asthenospheric mantle upwelling in mid-ocean-ridge and SSZ settings. A systematic comparison between four main genetic models provides insights into our understanding of the origin of ophiolite-hosted diamond and the formation of podiform chromitite. Diamond-bearing peridotites and chromitites in ophiolites are important objects to discover new minerals from the deep earth and provide clues on the chemical composition and the physical condition of the deep mantle.
Prostate-Specific Membrane Antigen (PSMA) Theranostics for Treatment of Oligometastatic Prostate Cancer
Authors: Plichta Kristin A. , Graves Stephen A. , Buatti John M.
Published: November 2021

Theranostics, a combination of therapy and diagnostics, is a field of personalized medicine involving the use of the same or similar radiopharmaceutical agents for the diagnosis and treatment of patients. Prostate-specific membrane antigen (PSMA) is a promising theranostic target for the treatment of prostate cancers. Diagnostic PSMA radiopharmaceuticals are currently used for staging and diagnosis of prostate cancers, and imaging can predict response to therapeutic PSMA radiopharmaceuticals. While mainly used in the setting of metastatic, castrate-resistant disease, clinical trials are investigating the use of PSMA-based therapy at earlier stages, including in hormone-sensitive or hormone-naïve prostate cancers, and in oligometastatic prostate cancers. This review explores the use of PSMA as a theranostic target and investigates the potential use of PSMA in earlier stage disease, including hormone-sensitive metastatic prostate cancer, and oligometastatic prostate cancer.
Profiling Attack against RSA Key Generation Based on a Euclidean Algorithm
Authors: de la Fe Sadiel , Park Han-Byeol , Sim Bo-Yeon , Han Dong-Guk , Ferrer Carles
Published: November 2021

A profiling attack is a powerful variant among the noninvasive side channel attacks. In this work, we target RSA key generation relying on the binary version of the extended Euclidean algorithm for modular inverse and GCD computations. To date, this algorithm has only been exploited by simple power analysis; therefore, the countermeasures described in the literature are focused on mitigating only this kind of attack. We demonstrate that one of those countermeasures is not effective in preventing profiling attacks. The feasibility of our approach relies on the extraction of several leakage vectors from a single power trace. Moreover, because there are known relationships between the secrets and the public modulo in RSA, the uncertainty in some of the guessed secrets can be reduced by simple tests. This increases the effectiveness of the proposed attack.
Effect of Chases with Renovation Techniques on the Load Carrying Capacity of Masonry Walls
Authors: Al-Sibahy Adnan , Edwards Rodger
Published: November 2021

Infrastructure through the masonry walls (for example, wiring and piping works) are usually installed using chases in different directions. Introducing these chases in a newly built wall will affect its overall load carrying capacity. However, there has thus far been very limited research into the effects of chases on the response and load carrying capacity of walls. This study has been undertaken to evaluate the structural behaviour of new masonry walls having chases in both horizontal and vertical directions and subjected to compression load throughout an extensive experimental programme. In addition, two renovation techniques have been proposed to infill the chases created in small scale walls (wallettes). The first technique involved the use of plastic wire mesh and cement mortar, while the second incorporated using galvanized steel channel together with the plastic wire mesh and cement mortar. Furthermore, a reference case of wallette without chases has been considered to enable reasonable comparisons to check the effect of the chases and the efficiency of the proposed renovation techniques. The outcomes of this study were used to modify the design equations proposed in the relevant codes of practice. The obtained results showed a notable reduction in the load carrying capacity of the masonry wall due to the introduction of the chases with a reduction percentage of 29% compared to the masonry wall without chase. The percentage decrease depends on the depth of the chase and the inclination angle of the load flow. The walls with horizontal chases exhibited more reduction in the load carrying capacity compared to those with vertical chases. The adopted renovation techniques using galvanized steel channel and/or plastic wire mesh with cement mortar recovered 55% and 93% of the lost load carrying capacity due to the presence of the chase and the failure was due to the de-bonded phenomena of the infill materials. Suitable factors of safety have been proposed to be incorporated in the compressive strength and modulus of elasticity formulas of the masonry walls of the BS EN codes.
Effectiveness of Ethyl Formate as a Fumigant of Blattella germanica and Periplaneta americana (Blattodea: Ectobiidae, Blattidae) in Cross-Border Trade Transportation
Authors: Kim Hyun-Kyung , Park Hanchan , Seok Seung-Ju , Kyung Yejin , Kim Gil-Hah
Published: November 2021

Cockroaches cause problems as pests not only locally in residential areas but also internationally, as they can disperse across borders in transport vessels. We investigated the effects of the ethyl formate (EF) fumigant on all developmental stages of Blattella germanica and Periplaneta americana. For B. germanica eggs, the hatching inhibition rate increased directly proportionately with the increasing treatment concentration of EF, but the 100% control was not observed. P. americana eggs did not show any fumigation effect, even after exposure to 60 mg/L of fumigant in a 12 L desiccator. Adults and nymphs of the two species showed various fumigation effects dependent on the concentration in the 12 L desiccator. When EF was applied at the lethal concentration for 99% mortality (LCT99) values of 35 mg/L for 4 h (78.5 mg·h/L) and 60 mg/L for 2 h (70.8 mg·h/L), respectively, adults and nymphs of both species had 100% mortality in a 0.65 m3 fumigation chamber with a 20% loading ratio. However, no significant difference from the control was observed in the egg stage of either species of cockroach. The results of this experiment indicate that EF can be used as a fumigant for cross-border transport vessels if the control period occurs during the cockroach developmental stage and continuous refumigation is performed.