bluuebunny/crossref_metadata_2025 huggingface dataset:
CT-morphologic and CT-textural patterns of response in inoperable soft tissue sarcomas treated with pazopanib—a preliminary retrospective cohort study
Authors: Esser Michael , Kloth Cristopher , Thaiss Wolfgang M , Reinert Christian P , Kraus Mareen S , Gast Gabriel CC , Horger Marius
Published: September 2019

Objective:

To analyze patterns of response in soft tissue sarcomas exposed to pazopanib using CT-morphologic and textural features and their suitability for evaluating therapeutic response.

Methods:

Retrospective evaluation of CT response and texture patterns in 33 patients (23 female; mean age: 61.2 years, range, 30–85 years) with soft tissue sarcomas treated with pazopanib from October 2008 to July 2017. Response evaluation was based on modified (m)CHOI-criteria and RECISTv.1.1 and classified as partial response (PR), stable disease (SD), progressive disease (PD). The following CT-texture (CTTA)-parameters were calculated: mean, entropy and uniformity of intensity/average/skewness/entropy of co-occurrence matrix and contrast of neighboring-gray-level-dependence-matrix.

Results:

Following mCHOI-criteria, 12 patients achieved PR, 7 SD and 14 PD. As per RECISTv.1.1 9 patients obtained PR, 9 SD and 15 PD. Frequent patterns of response were tumor liquefaction and necrosis (n=4/33, 12.1% each). Further patterns included shrinkage and cavitation (n=2/33, 6.1% each). In responders, differences in mean heterogeneity (p=0.01), intensity (p=0.03), average (p=0.03) and entropy of skewness (p=0.01) were found at follow-up whereas in non-responders, CTTA-parameters did not change significantly. Baseline-CTTA-features differed between responders and non-responders in terms of uniformity of skewness (p=0.045). Baseline-CTTA-parameters did not correlate with any morphologic response pattern.

Conclusion:

Most frequent patterns of response to pazopanib were tumor liquefaction and necrosis. Single CT-textural features show strong association with the response to pazopanib—although limited in relation to specific response patterns.

Advances in knowledge:

Tumor liquefication and necrosis are important patterns of response to pazopanib. CT-texture analysis has limited associations with specific response patterns.
Effects of self-experimentation during practical classes on student learning
Authors: de Leão e Neves Eduardo A.M. , Campos Caldas Rosa E.C. , Fonseca Welker A.
Published: September 2019

Background: This article reports an experiment based on the measurement of the academic achievement of students submitted to self-experiments during practical classes compared with students who attended regular practical classes (control group) to assess whether this intervention could help assess the influence of self-experiments on student learning. Methods: This study involved 71 students in the second terms of the degree of Bachelor of Pharmaceutical Sciences, studying the Cell Biology unit. Experiments were conducted using the students themselves as subjects under conditions that mimic situations observed in daily life, fasting and ingestion of carbohydrates. The performance of students in health college student assessments and the degree of motivation in performing these experiments was assessed at the Anhanguera college, Brasilia, Brazil. In total, 33 students (46.5%) participated actively in the experiment and the rest only observed the experiment carried out by the first group. In Cell Biology, the students study cell types, cell components and their respective functions, during one term, with a total workload of 60 h. Results: In the test that preceded the experiment carried out in the present study, the grades of the students that participated actively and of those that only observed were not statistically different (p > 0.05). In the test applied after the experiment, both groups reached higher grades (p < 0.01), but the individuals that participated actively in the experiment obtained higher grades than those that only observed it (p < 0.05).

Conclusions: The findings of this study indicate that active learning, in which the students use their own organism and blood in practical classes, can increase their grades in knowledge tests. The teaching tool showed in the present study is a positive alternative for university students in health sciences.
Discretionary Remote Working Helps Mothers Without Harming Non-mothers: Evidence from a Field Experiment
Authors: Sherman Eliot L.
Published: September 2019

Because mothers remain disproportionately responsible for childcare, the daily requirement for physical presence at work disadvantages them compared with otherwise equivalent men and childless women. Relaxing this requirement may therefore enhance the well-being and productivity of working mothers. I tested this idea with a randomized field experiment, using a within-subjects analysis from a repeated crossover design. The 187 participants in the experiment, which ran for four weeks and yielded 748 person-week observations, revealed a preference for about two remote working days per week. I observed no significant differences in the uptake of remote working days between men, women, parents, nonparents, fathers, and mothers. Mothers reported meaningfully reduced family–work conflict during remote working weeks, but fathers did not. Remote working generally increased job performance, but the effect was greatest for mothers. The coordination costs of remote working, with respect to coworker helping and job interdependence, did not appear prohibitive. Interviews with study participants corroborate and contextualize these findings.

This paper was accepted by Olav Sorenson, organizations.
The Long-term and Spillover Effects of Price Promotions on Retailing Platforms: Evidence from a Large Randomized Experiment on Alibaba
Authors: Zhang Dennis J. , Dai Hengchen , Dong Lingxiu , Qi Fangfang , Zhang Nannan , Liu Xiaofei , Liu Zhongyi , Yang Jiang
Published: September 2019

Dynamic pricing through price promotions has been widely used by online retailers. We study how a promotion strategy, one that offers customers a discount for products in their shopping cart, affects customer behavior in the short and long term on a retailing platform. We conduct a randomized field experiment involving more than 100 million customers and 11,000 retailers with Alibaba Group, one of the world’s largest retailing platform. We randomly assign eligible customers to either receive promotions for products in their shopping cart (treatment group) or not receive promotions (control group). In the short term, our promotion program doubles the sales of promoted products on the day of promotion. In the long term, we causally document unintended consequences of this promotion program during the month after our treatment period. On the positive side, it boosts customer engagement, increasing the daily number of products that customers view and their purchase incidence on the platform. On the negative side, it intensifies strategic customer behavior in the posttreatment period in two ways: (1) by increasing the proportion of products that customers add to their shopping cart conditional on viewing them, possibly because of their intention to get more shopping cart promotions, and (2) by decreasing the price that customers subsequently pay for a product, possibly because of their strategic search for lower prices. Importantly, these long-term effects of price promotions on consumer engagement and strategic behavior spill over to sellers who did not previously offer promotions to customers. Finally, we examine heterogeneous treatment effects across promotion, seller, and consumer characteristics. These findings have important implications for platforms and retailers.

This paper was accepted by Vishal Gaur, operations management.
Architecture of Atwood Machine Props with Sensor-based Passive Infrared
Authors: Saraswati Dandan Luhur , Putri Delia Achadina
Published: September 2019

The aim of this research is to develop Atwood machine propswith sensor-based PIR (Passive Infrared) to determine the acceleration value of earth gravity. This type of research is an experiment conducted in the physics laboratory of Universitas Indraprasta PGRI. Atwood machine was developed by using PIR (Passive Infrared) sensors to detect the movement of the objects used. Based on the trialof the result of the data analysis experiment tool, the acceleration of gravity was obtained (9.87 ± 0.08) m/s2. Whereas the value of acceleration of gravity in the literature is 9,80665 m/s2. The obtained results shows that the acceleration of gravity obtained in this research is not much different from the acceleration value of gravity  found in the literature so that Atwood machine tool that is developed by using PIR sensor is recommended to be one alternative tool in determining the acceleration of earth gravity.
Two distinct diseases
Authors: Chapman Stella
Published: September 2019

Stella Chapman MRCVS elaborates on equine gastric ulcer syndrome
Parathyromatosis: a very rare cause of recurrent primary hyperparathyroidism – case report and review of the literature
Authors: Haciyanli M , Karaisli S , Gucek Haciyanli S , Atasever A , Arikan Etit D , Gur EO , Acar T
Published: September 2019

Parathyromatosis is a rare entity and usually appears as a consequence of the seeding on previous parathyroid surgery which was applied for the secondary hyperparathyroidism. A 63-year-old woman presented with a history of subtotal thyroidectomy 20 years ago and parathyroidectomy due to primary hyperparathyroidism (PHPT) four years ago. Imaging methods revealed multiple parathyromatosis foci on subcutaneous tissue of the neck. En-bloc resection was performed and pathological examination confirmed the diagnosis of parathyromatosis. After an uneventful 10 months, biochemical and radiological tests revealed recurrence on bilateral thyroid lodges. En-bloc resection was performed. The patient has remained well for 24 months after the second operation and has been followed-up with normal parathormone and serum calcium values. To the best of our knowledge, this report describes the twenty-first case of parathyromatosis in PHPT setting in the literature. It should be kept in mind that parathyromatosis may recur at different sites in the neck even in patients with PHPT.
African People, Education for Liberation & Staying Human: Reflections on Walter Rodney and the Pan-African / Black Liberation Tradition
Authors: King Joyce E.
Published: September 2019

On March 25th, 2017, Dr. Joyce E. King delivered this talk as the day two keynote of the 14th Annual Walter Rodney Symposium at the Atlanta University Center Robert W. Woodruff Library, Atlanta, Georgia.
Gender, politics and the tweeted campaign: tweeting about issues during the UK’s 2017 general election campaign
Authors: Ross Karen , Jansen Marloes , van de Wijngaert Lidwien
Published: September 2019

We aimed to explore the extent to which women and men politicians tweet about different issues. We captured 82,890 tweets sent by Labour and Conservative politicians during the 2017 British general election campaign, analysed 38,255 original tweets and identified 7,651 tweets that mentioned a political issue. We also qualitatively analysed 210 tweets to better understand the content, tone and orientation of content. We suggest that gender and party, both together and separately, exert some influence on tweet topic. However, we also suggest that the particular interests of individual politicians play a role in determining the focus of their issue-based tweets.
Characteristics of Women Who Present for Abortion Beyond the Legal Limit in Flanders, Belgium
Authors: Van de Velde Sarah , Van Eekert Nina , Van Assche Kristof , Sommerland Nina , Wouters Edwin
Published: September 2019

CONTEXT

Women who seek abortion care beyond the first trimester of gestation are often in a vulnerable socioeconomic position with limited social support, and in Belgium, the details of their circumstances are insufficiently understood. A better understanding of this group is essential to a critical evaluation of Belgian abortion policy, which restricts abortions on request after the first trimester.

METHODS

Anonymized patient records were collected between 2013 and 2016 from LUNA centers, which are non‐hospital‐based abortion clinics in Flanders. Logistic regression analyses were used to identify associations between women's characteristics and whether they presented within or beyond the legal limit, which was 13 weeks and 1 day at the time of the study.

RESULTS

A total of 28,741 women requested an abortion, and 972 individuals (3.4%) presented beyond the legal limit; 29% of these latter women were unable to receive abortion care as a result of the mandatory six‐day waiting period. Characteristics positively associated with presenting beyond the limit, instead of beforehand, were being younger than 20, as opposed to 20–24 (odds ratio, 1.7); receiving a primary, lower secondary, upper secondary or special‐needs education, rather than a higher education (1.8–3.1); being unemployed, rather than employed (1.3); and holding Belgian rather than a foreign nationality (0.8). Being accompanied by someone to the LUNA center (0.8), having irregularly (0.6) or regularly used contraceptives (0.7), and having ever had an abortion (0.8) were negatively associated with presenting beyond, rather than before, the limit.

CONCLUSIONS

A fuller consideration of patients’ characteristics when evaluating Belgian abortion policy is needed to ensure that the needs and rights of socioeconomically vulnerable women are addressed.
Stories with deep roots: Cultivating community–university relationships to facilitate the creation of Gwa’sala-’Nakwaxda’xw children’s stories
Authors: Hemphill Lucy , Rosenblum Daisy
Published: September 2019

Bak'wamk'ala is a language spoken on north-eastern Vancouver Island and on the islands and along coastal waterways nearby. One of the joys of life in these territories is the abundance of delicious berries that ripen throughout the summer: ťsagał (‘thimbleberries’), k'amdzakw (‘salmonberries’), gwadam (‘huckleberries’), ŉak'wał (‘salalberries’) and more. Kwakwaka'wakw culture includes a long tradition of knowledge and technologies related to berry-picking: special baskets, protocols for picking, songs and stories. Children accompany their parents while berry-picking as babies in carriers and gradually walking alongside with their own small baskets; for this reason, berry-picking is an especially suitable topic for a children’s book seeking to highlight and foreground Kwakwaka'wakw culture for Kwakwaka'wakw children (and others). We share here the text of a children’s book about picking thimbleberries by Lucy Hemphill (Gwa’sala-’Nakwaxda’xw), and a reflection written by Ms Hemphill and Daisy Rosenblum, a professor in the First Nations and Endangered Languages Program at the University of British Columbia, which describes the iterative process of including Bak'wamk'ala in the English version of the story, and planning for the Bak'wamk'ala language version of the book. Through our reflection, we discuss the choice of the story’s theme, the value of written resources created for languages with previously oral traditions and the challenges inherent in such processes of creation.
Writing the self, decolonization and gaining through translation
Authors: Hujon Janet
Published: September 2019

The Khasis, who refer to themselves as Children of the Seven Huts, are an Indigenous ethnic group in Meghalaya (‘the abode of clouds’) in north-eastern India. As early as 1824, the Baptist mission in Serampore had translated a portion of the Bible into Khasi using the Bengali script. But Khasis found the script difficult to read and further efforts were discontinued. So, until the arrival of the Welsh Mission, when Thomas Jones transcribed the Khasi language into the Roman Script in 1841, the language remained primarily oral. While reading and writing ensured progress in literacy, the use of English as the medium of instruction and the accompanying imposition of western values had serious cultural consequences. The mother tongue was considered inferior, oral traditions that had long been channels of a unique world-view were marginalized and the old ways of thinking based on a profound respect for the natural world were gradually eroded. This was because an oral culture was considered less than one possessing the written word. But fortunately especially in the absence of written documentation, remembering, telling and sharing have always played a significant part in Khasi social life. Kynmaw is the Khasi word for remember and as Nigel Jenkins points out in his book Gwalia in Khasia, the word is ‘megalithic’ because it suggests to make or ‘mark with a stone’ (1995: 5), immediately recalling the monoliths raised to commemorate past lives. Kynmaw is also a chilling warning – ‘remember’, or else’ – and that is what this article sets out to do: to rekindle the old reverences for a language teaching us a way to be to halt the dangers of an ongoing cultural forgetting.
Reflecting on multicultural relations in the community outreach programme
Authors: Natadjaja Listia
Published: September 2019

The community outreach programme (COP) is one of the service-learning programmes in Petra Christian University involving many students from the university and abroad. The programme sends these students to live and conduct community developments in small villages in Indonesia. When I became a field supervisor of the COP in 2010 and 2016, I became aware of the multicultural relations among the students and the community. Although the COP mostly focuses on improving community welfare in terms of education, income, sanitation, etc., there are always multiple processes of cultural learning. This article is based on my experiences and personal reflections, supported by data through reflection review, field observation, informal interviews and interactions with the students and the community. For students, a multicultural environment not only provides different experiences but also life lessons in interacting with especially rural communities. Living within the community made the students more empathetic. In turn, the community mostly felt positive about the impact of the programme, which is real and substantial, and the unforgettable moments of interactions with international students. These multicultural relations reveal values of respecting other cultures, developing attitudes, and broadening beliefs between the students and the community.
On the use of vocabularies of geometric forms in ornamental pattern design
Authors: Hindocha Ameet
Published: September 2019

This article examines the development and use of vocabularies of shapes constructed using geometric principles as a basis for ornamental pattern design. Through a combination of digital fabrication techniques and printmaking, I have developed a process for freely exploring geometric ornamentation based on compatible vocabularies of shapes. The process highlights the correlation between the use of these vocabularies and language as a medium of expression. It can also provide an insight into how the universality of the visual expression of mathematical concepts helps us perceive the nature of the world around us.
A thing to hold: The visual language of the book form
Authors: Roscoe Lucy
Published: September 2019

This article considers the book form itself as an ornamental object. The binding, paper and ink appeal to the senses and all add to experience of the reader. The future is a place of e-books, online publications and Instagram posts, and yet this arguably makes the carefully considered design of the book form even more important in the physical books that we do chose to view. The study examines a series of examples, drawing from artists' books, pop-up books and mainstream publishing. The work draws strongly on the collection of pop-up books at the National Library of Scotland and the artists' book collection at Edinburgh College of Art, looking at both historical and contemporary works. Initially exploring how the form of the book itself can visually communicate a narrative, the study goes on reflect on the emotion associated with opening a pop-up book, as if in the presence of a theatrical production, made more extreme by the embellishments employed. The place of the book form within a digital world is considered and, finally, the emergence of decorative books in the form of colouring books related to mindfulness.
Harmonic function and modality in classic heavy metal1
Authors: Lilja Esa
Published: September 2019

This article explores harmonic function, modality and guitar distortion in so-called classic heavy metal. I suggest a dual framework for analysing heavy metal, including such mirror-symmetries as ‘major’/‘minor’, ‘sharp’/‘flat’, ‘bright’/‘dark’, ‘dominant’/‘subdominant’ and ‘authentic’/‘plagal’. My central aim is to demonstrate that heavy metal harmony tends towards plagal systems and darker modes, and yet has constant major elements added from the distorted power chords.
Distortion, restriction and instability: Violence against the self in depressive suicidal black metal
Authors: Coggins Owen
Published: September 2019

In the underground subgenre of depressive suicidal black metal (DSBM), extremes of violence against the self are presented in combination with a restrictive version of black metal. Album covers feature explicit photographs of self-cutting or drawings of suicide by hanging; vocals are tortured screams expressing extreme suffering, and guitar sounds are so distorted that they begin to approach an ambient atmospheric blur. Given the history of concern about metal and its health implications, I investigate DSBM as a case in which representation of harm in music is overt, explicit and extreme, yet the health impact of the music is undetermined. I discuss how different modalities of distortion and restriction may connect the sound of DSBM to themes of violence against the self, presenting a theoretical framework for approaching DSBM as music which negotiates a complex economy of the staging and control of violence with respect to the self.
Las devociones marianas españolas en el Brasil colonial
Authors: Castro Brunetto Carlos Javier
Published: September 2019

El objetivo de este artículo es analizar la presencia de las devociones españolas de la Virgen María y su arraigo en diversas regiones de Brasil, un tema poco conocido en el ámbito de la historia religiosa y cultural del país. Estudiaremos su implantación, amparándose en el origen devocional español y cómo encontraron vías de expresión espiritual y artística en el seno de la sociedad colonial brasileña.
Las oportunidades para la corrupción administrativa ofrecidas por el ordenamiento jurídico brasileño: una visión crítica
Authors: Santano Ana Claudia , Blanchet Luiz Alberto
Published: September 2019

Con el aumento del interés por parte de la academia de abordar el tema de la corrupción, es importante avanzar en el sentido de verificar los factores que facilitan dicha práctica en la esfera administrativa. La principal hipótesis es que el propio Derecho crea oportunidades para la corrupción en el lugar de combatirla. A partir de un análisis bibliográfico crítico, se intenta demostrar que la legislación que se refiere a la contratación pública favorece prácticas corruptas, por medio de un examen de los costes y de los beneficios, evaluando el grado de favorecimiento que la propia ley concede a los agentes que pretenden actuar de esta manera.
DIETOTERAPIA NA EQUIPE MULTIDISCIPLINAR PARA O TRATAMENTO DE CÂNCER DE MAMA
Authors: Carvalho Ana Clara Lacerda Cervantes de , Ferreira Júnior Waldeir De Souza , Menezes Suanam Altair Tavares de , Bueno Mariana Machado
Published: September 2019

Introdução: o câncer de mama é uma das principais neoplasias que mais acometem mulheres no Brasil, estimando 59.700 novos casos nos anos de 2018 e 2019, consiste nas mudanças da expressão do padrão de genes que atuam nas sinalizações das células mamárias provocando várias complicações, como a desnutrição. Objetivo: o objetivo foi analisar a conduta nutricional no tratamento para o câncer de mama ofertado pela equipe interdisciplinar. Método: trata-se de uma revisão sistemática sem metanálise da literatura nas bases de dados LILACS e SCIELO, com buscas realizadas em julho de 2019, utilizando os descritores associados ao operador booleano (AND): Dietoterapia. Multidisciplinar. Câncer de mama. Os critérios de inclusão foram estudos em português e inglês, publicados entre os anos de 2010 a 2018, excluindo os que não estavam disponíveis na integra ou não abordassem o assunto. Resultados: Foram selecionados 14 artigos, após a aplicação dos critérios, restaram 8 artigos. Apesar do bom prognóstico, se diagnosticado precocemente, na saúde pública, verificam-se atrasos dos atendimentos no decorrer do aparecimento dos sintomas e no tratamento, mantendo as taxas de mortalidade elevadas. Por essa razão, a terapia ofertada pela equipe de saúde deve promover o cuidado integral para a compressão íntegra da doença. No âmbito nutricional, o profissional auxilia na redução da sintomatologia causada pela neoplasia e terapêutica, na manutenção do peso, tratando principalmente, a desnutrição, necessitando de maior aporte protéico no consumo pela perda e degradação de massa magra, a deficiência de vitaminas e minerais pelo aumento do gasto consumptivo da doença e na ingesta alimentar insuficiente, ofertando hortaliças e alimentos de baixo teor de gordura, evitando o consumo de embutidos e carnes vermelhas; na diminuição dos efeitos colaterais proporcionados pelos métodos interdisciplinares, dessa forma a avalição nutricional atua para manter o estado adequado do indivíduo e a melhor resposta ao tratamento, sendo utilizada desde a antropometria, exames bioquímicos e avaliação clínica, apesar do caráter extenuante da doença, o sobrepeso e a obesidade são fatores de risco. Conclusão: a terapia nutricional é, portanto, adequada, preconizando as recomendações energéticas, ao tipo de neoplasia, grau de manifestação no paciente e com o estado clínico, sendo fundamental o acompanhamento nutricional em uma equipe de saúde, respeitando a particularidade do paciente.
NÓDULO DE PLUMMER: UM RELATO DE CASO
Authors: Costa Pedro Augusto Silva da , Ferreira Gabriel Da Fonseca Soares , Ferreira Hélio Fillipe da Silva Ferreira , Teixeira Pedro Lima Verde , Lemos Alyne Layane Pereira
Published: September 2019

Introdução: A doença de Plummer, também conhecida como Adenoma Tireoidiano Tóxico, é um tumor benigno ocasionado pelo crescimento excessivo e a transformação estrutural/funcional de uma área do parênquima tireoidiano, sendo a terceira causa mais comum de hipertireoidismo no Brasil. Trata-se de uma patologia que acomete mais o sexo feminino, em pacientes entre 30 e 60 anos. O quadro clínico consiste em palpitações, insônia, alterações no humor e tremores nas extremidades, presente em nódulos maiores do que 3cm de diâmetro. O diagnóstico é feito através da clínica, exames laboratoriais e Cintilografia de Tireoide. O tratamento pode ser feito através de iodo radioativo, drogas antitireoidianas, escleroterapia com etanol ou cirurgia. Objetivo: Relatar o caso de um paciente com diagnóstico de nódulo de Plummer. Relato de Caso: Paciente do sexo masculino, 40 anos, compareceu ao consultório de endocrinologia encaminhado pelo cardiologista devido a episódios de palpitações, com TSH abaixo da normalidade e passado de nódulo na tireoide. Paciente nega perda de peso, alterações de humor e tremores nas extremidades, mas relata insônia. Ao exame físico, apresentou nódulo palpável em lobo direito de tireoide de aproximadamente 3cm. Exames laboratoriais apontaram TSH 0,21 mU/L e T4 Livre 0,97 ng/dl, caracterizando um hipertireoidismo subclínico. Foi solicitado USG de Tireoide com Doppler o qual apresentou um nódulo misto em LD predominantemente cístico medindo 3,8x3,4x2,3cm com TI-RADS 4a. Realizou cintilografia de tireoide evidenciando lobo direito hipercaptante, com supressão do restante do parênquima sugestivo de doença de Plummer. PAAF resultou em Bethesda 2 (bócio colóide) Conclusão: Este caso ilustrou a apresentação clínica de um paciente com hipertireoidismo subclínico devido a doença de Plummer. Palavras-chave: Tireoide; Nódulo de Plummer; Hipertireoidismo.
CUIDADOS PALIATIVOS: QUALIDADE DE VIDA E PRESERVAÇÃO DA DIGNIDADE HUMANA
Authors: Araújo Paula Gabriella De Sousa , Sousa Helen Fernanda De Oliveira
Published: September 2019

Introdução: Convencionalmente o termo palliun significa manto, coberta, manifestando a ideia de que os cuidados paliativos estão embasados não no ato de curar e sim no sentido mais amplo do cuidado. Nesse processo que abrange principalmente os pacientes oncológicos, a morte é vista como a terminalidade do corpo físico, uma etapa normal da vida, fato que resgata a importância da preservação do bem-estar e dignidade humana. Nessa perspectiva, indivíduos em situações terminais recebem assistência multidisciplinar que garantem controle da dor física e dos problemas psicossociais. A equipe é composta de acordo com as necessidades de cada paciente e normalmente é instituída por médico, enfermeiro, psicólogo, farmacêutico, fisioterapeuta, nutricionista, assistente social, dentista, terapeuta ocupacional e assistente espiritual que trabalham em conjunto para beneficiar tanto o paciente em sofrimento quanto a família. Objetivo: Acatar a relevância dos cuidados paliativos na preservação da qualidade de vida do paciente no que se refere aos âmbitos sociais, psicológicos e espirituais.  A conservação da dignidade até o fim da vida é um princípio moral baseado nos direitos humanos, desse modo reconhecer o paciente terminal não apenas como uma doença é o passo inicial para um tratamento humanizado e efetivo. Métodos: Foi elaborado a partir de revisão de literatura obtida por análise de artigos científicos que tem como base de dados Google Acadêmico e SCIELO. Os principais descritores utilizados foram cuidados paliativos, qualidade de vida e pacientes terminais. Resultados: Os pacientes terminais sob cuidados paliativos conseguem obter melhorias nos sintomas de sua doença, além de desfrutar da sensação de não ser um incômodo para seus cuidadores, já que sua capacidade funcional e autonomia são beneficiados. Conclusão: O bem-estar físico, mental, social e espiritual são direitos inegáveis a qualquer ser humano que esteja ou não passando por algum sofrimento. Pacientes oncológicos sem respostas a nenhuma terapia convencional merecem desfrutar o restante de suas vidas de forma plena, sem dores e preocupações adicionais. Os cuidados paliativos garantem alívio para as aflições do corpo e da alma e trabalham de forma interdisciplinar para que a família e/ou cuidadores sejam assistidos com a mesma cautela e preocupação. Desse modo, tal processo permite que a morte deixe de ser um paradigma e passe a ser vista de forma humanizada.
A COMPARATIVE STUDY OF DATA-DRIVEN MODELING METHODS FOR SOFT-SENSING IN UNDERGROUND COAL GASIFICATION
Authors: Kačur Ján , Durdán Milan , Laciak Marek , Flegner Patrik
Published: September 2019

Underground coal gasification (UCG) is a technological process, which converts solid coal into a gas in the underground, using injected gasification agents. In the UCG process, a lot of process variables can be measurable with common measuring devices, but there are variables that cannot be measured so easily, e.g., the temperature deep underground. It is also necessary to know the future impact of different control variables on the syngas calorific value in order to support a predictive control. This paper examines the possibility of utilizing Neural Networks, Multivariate Adaptive Regression Splines and Support Vector Regression in order to estimate the UCG process data, i.e., syngas calorific value and underground temperature. It was found that, during the training with the UCG data, the SVR and Gaussian kernel achieved the best results, but, during the prediction, the best result was obtained by the piecewise-cubic type of the MARS model. The analysis was performed on data obtained during an experimental UCG with an ex-situ reactor.
HEAT FLUX JUMP METHOD AS A POSSIBILITY OF CONTACTLESS MEASUREMENT OF LOCAL HEAT TRANSFER COEFFICIENTS
Authors: Solnař Stanislav , Dostál Martin
Published: September 2019

This article deals with the derivation of the temperature response of the finite thickness wall, which is heated by heat flow, as a possibility to measure the local values of the heat transfer coefficient with a very high spatial resolution. In addition to its own experimental measurement technique, it is also possible to use this derivation to describe the gradual heating of the wall while using the temperature oscillation (TOIRT) method for the heat transfer measurement. The system of the partial differential equations and the boundary and initial conditions is solved by a transformation into Laplace’s space, where the task is easier to solve. At the end of the article, the results of the analytical solution are compared with a numerical solution of this problem.
Ein Leben, das für alle lebbar ist?
Authors: Tanyilmaz Tugba , Ünsal Nadiye , Yilmaz-Günay Koray
Published: September 2019

Die »Flüchtlingskrise« von 2015/2016 hat mit unglaublicher Geschwindigkeit und Intensität ein Thema in die (queere und nicht-queere) Öffentlichkeit gespült, das trotz des zum Teil ausgiebigen queer-migrantischen Engagements jahrzehntelang kaum wahrgenommen worden war: Queere Lebensweisen und Migration müssen zusammen-gedacht werden. Bundesweit haben sich in kürzester Zeit zahlreiche Unterstützungsinitiativen und -netzwerke gegründet, es gibt politische Diskussionsrunden, Fortbildungen, Fachtagungen, Spendensammlungen, Veröffentlichungen und mit kleinem oder großem Geld unterstützte Projekte - darunter nicht zuletzt auch Gemeinschaftsunterkünfte für asylsuchende Lesben, Schwule, Bisexuelle, Trans* und Inter* (LSBTTIQ). So schnell das Interesse an einem solchen »Nischen-Thema« im Jahr 2015 entstanden ist, so wenig wird es sich verstetigen lassen, wenn die Verschränkungen von Migration und Fragen von sexueller Orientierung und Geschlechtsidentität nur als vorübergehendes »Problem« wahrgenommen werden. Nach einer Reflexion unserer eigenen Praxis im Umgang mit geschlechtlicher und sexueller Vielfalt beim Migrationsrat Berlin (MRB) wollen wir mit einem kleinen Exkurs zu Intersektionalität herausarbeiten, warum ein Exzeptionalismus, der einzelnen Gruppen von Geflüchteten ausnahmsweise bessere Lebensbedingungen gewährleistet, auch dazu dient, systematisch schlechtere Lebensbedingungen für andere zu legitimieren. Wir wollen damit zeigen, wie das Engagement für queere Geflüchtete zu einem Engagement für eine Verbesserung des Lebens aller ausgeweitet werden kann.
Environmental Change and Sustainability of Indigenous Languages in Northern Alaska
Authors: Reo Nicholas J. , Topkok Sigvanna Meghan , Kanayurak Nicole , Stanford James N. , Peterson David A. , Whaley Lindsay J.
Published: September 2019

Relatively few people under the age of 60 are fluent speakers of the various Indigenous languages of Alaska. Concurrently, climate change is severely impacting Alaska and its residents, where environments are changing far more rapidly than the majority of the planet. These factors complicate the land-language nexus and may have implications for the sustainability of Indigenous languages in Alaska and other parts of the Arctic. In this collaborative, community-centered project, we spoke with Iñupiaq and Yupik language speakers to learn how rapid environmental change affects heritage language discourse practices and how generational gaps in levels of heritage language fluency affect safety and efficacy of customary and traditional land use activities. The results show how local community choices and attitudes are reflecting and constructing dynamic ecologies of language, culture, and environment. Iñupiaq and Yupik languages provide important forms of socio-cultural resilience because they embed the past, yet are inherently dynamic. Community-driven social practices that promote increased local heritage language use can lead to new, creative language domains, new expressions of Indigenous culture, and new Indigenous stances toward a changing environment.
The effect of 10-week swimming and bosu exercises on dynamic balance parameter in 8-10 years old boys
Authors: Kılınç Hilal , Temur Hacı Bayram , Mollaoğulları Hacalet
Published: September 2019

Bu çalışma 8-10 yaş arası erkek çocuklarda yüzme egzersiz ve bosu çalışmalarının dinamik dengeye etkisini incelemek amacıyla yapıldı. Yaşları ortalaması 8,9333±,78492 yıl olan 30 katılımcı veli ve antrenörlerinden gönüllü katılımları ile ilgili aydınlanmış̧ onamları alınarak çalışmaya dahil edildi. Bunların 20' si egzersiz grubu diğer 10'u da kontrol grubudur. Egzersiz grubunun en az 1 yıl yüzme eğitimi almış olmalarına ve haftada 3 gün düzenli olarak yüzme antrenmanı yapıyor olmalarına dikkat edildi. Egzersiz grubu rastgele yöntemle 2 gruba ayrıldı. Birinci gruba yüzme ve bosu çalışmaları, ikinci gruba ise sadece yüzme egzersizleri yaptırıldı. Bu çalışma 10 hafta süreyle uygulandı. Katılımcıların antropometrik ölçümler ile dinamik denge ölçümleri planlanan antrenman programı öncesi ve sonrası olmak üzere iki defa alındı. Çalışma Van Olimpik yüzme havuzunda uygulandı. Verilerin analizinde SPSS 21 paket programı kullanıldı.  Analizler sonucunda yüzme eğitimi alan grubun A (Anterior), PM (Posteromedial) ve PL (Posterolateral) ön test - son test ölçüm  değerleri arasında anlamlı (p<0,01) fark olduğu saptandı. Yine yüzme ve bosu eğitimi alan grubun PM ve PL ön test - son test ölçüm  değerleri arasında anlamlı (p<0,01) fark olduğu belirlendi. Seçilmiş değişkenlerin ön test- son test ölçüm değerleri arasındaki farkların gruplar arasında anlamlı (p<0,05)  bir farklılığın olmadığı görüldü.  
​Extended English summary is in the end of Full Text PDF (TURKISH) file.
 
Özet
This study was carried out to investigate the effect of swimming exercise and bosu studies on dynamic equilibrium in 8-10 years old boys. They were included in the study by taking their enlightened consent about their voluntary participation from 30 participants parents and coaches with an average age of 8,9333 ±, 78492 years. 20 of them were exercise group and 10 of them were control group. The exercise group had at least 1 year of swimming training and swimming training 3 days a week was paid attention to be doing regularly. The exercise group was randomly divided into two groups. The first group had swimming and bosu exercises and the second group had only swimming exercises. This study was performed for 10 weeks. The participants' anthropometric measurements and dynamic balance measurements were taken twice before and after the planned training program. The work was carried out at the Olympic swimming pool in Van. SPSS 21 package program was used to analyze the data. As a result of the analyzes, it was found that there was a significant difference (p<0.01) between the A (Anterior), PM (Poateromedial) and PL (Poaterolateral) pre-test and post-test measurements of the swimming group. It was determined that there was a significant difference (p <0.01) between the PM and PL pretest - posttest measurements of the group receiving swimming and bosu training. There was no significant difference (p <0.05) between the pre-test and post-test values ​​of the selected variables.
Geometric estimates for complex Monge–Ampère equations
Authors: Fu Xin , Guo Bin , Song Jian
Published: September 2019

We prove
uniform gradient and diameter estimates for a family of geometric complex Monge–Ampère equations. Such estimates can be applied to study geometric regularity of singular solutions of complex Monge–Ampère equations. We also prove a uniform diameter estimate for collapsing families of twisted Kähler–Einstein metrics on Kähler manifolds of nonnegative Kodaira dimensions.
Utilizing Rasch analysis to establish the psychometric properties of a concept inventory on concepts important for developing proficiency in organic reaction mechanisms
Authors: Nedungadi Sachin , Paek Sue H. , Brown Corina E.
Published: September 2019

Undergraduate organic chemistry has been found to be historically difficult for students and one area where students struggle is organic reaction mechanisms. The difficulties students face with reaction mechanisms has been a source of interest in chemical education research but most studies done have been purely qualitative. An assessment tool that could be used on a large-scale for instructors to gauge the difficulties their students face, would be useful. The aim of this pilot study is to use Rasch analysis to establish the validity and reliability of the concepts important for developing proficiency in organic reaction mechanisms inventory (RMCPI). The test, containing 25 items, was administered to first semester organic chemistry students (N = 44) at a mid-sized university. The data was analyzed using Rasch techniques to explore the dimensionality of the instrument, the difficulty of the items, the item fit, and the reliability. The results indicate that the instrument is unidimensional and most of the items fit well to the dichotomous Rasch model. The test was found to be difficult and this will be explored further by increasing the sample size, administering the test to students from other universities and increasing the number of items on the inventory.
Dynamic absorption efficiency of paracetamol powder in microwave drying
Authors: Zhai Di , Zhang Fucheng , Wei Cong , Shang Xiaobiao , Chen Junruo , Liu Meihong , Peng Jinhui
Published: September 2019

In microwave drying technology, research into the dynamic absorbing properties of the powder is indispensable. In this study, the reflection loss coefficient of paracetamol powder under different temperature, water content, and thickness was calculated based on the principle of electromagnetic wave transmission. The results show that the absorption performance of powder fluctuates dynamically with a series of absorption peaks, and the position of the absorption peak shifts toward the smaller thickness direction as the water content increases or the temperature rises. Because of the influence of the powder thickness on absorbing efficiency, the powder thickness should be adjusted in real time to increase drying efficiency. This study provides the thickness range for which the absorption performance of paracetamol powder under different conditions is over 99%. This study is of great significance for understanding the drying mechanism and optimizing process parameters for microwave drying of pharmaceutical powder.
The relationship between, burnout, personality, and emotional intelligence in clown doctors
Authors: Dionigi Alberto
Published: September 2019

Despite increasing interest in healthcare clowning, especially to evaluate its effectiveness in a large variety of settings, no investigations have been oriented toward exploring the potential risks associated with burnout in clown doctors. This paper aims to investigate the relationship between personality traits, emotional intelligence, and burnout and to predict the burnout levels of 160 Italian clown doctors. The multiple linear regression findings showed that the best predictor for emotional exhaustion was neuroticism and for personal accomplishment were consciousness and emotional intelligence, while no correlations were found between the variables taken into account and depersonalization. These findings highlighted how specific personality traits are linked to different dimensions of job burnout and were discussed in the context of clown doctors’ burnout.
Alternative Tempering of Sugar-Free Dark Chocolates by βv Seeding: Sensorial, Micro-Structural and Some Physical Properties and Volatile Profile
Authors: Toker Omer Said , Oba Sirin , Palabiyik Ibrahim , Rasouli Pirouzian Haniyeh , Konar Nevzat , Artik Nevzat , Sagdic Osman
Published: September 2019

In this study, sugar-free dark chocolate was produced from isomalt and maltitol by βV seeding technique as an alternative to conventional tempering process. The effect of βV seed concentrations on the particle size distribution, textural, rheological and melting properties of the end products was studied, and the results were compared with those of conventional sugar-free dark chocolates. For this aim, conched dark chocolates were melted and crystallized with βV seeds added at different concentrations (0.5, 0.6, 0.7, 0.8, 0.9 and 1.0 %, m/m). Conventional tempering process was performed by using temper machine (47–27–32 °C). Brightness, chroma, whiteness index and tetramethyl pyrazine content (as marker compounds of dark chocolate volatile compound) were not influenced by seeding technique compared to conventional tempering method. The water activity of the dark chocolate samples was substantially affected by βV seed level according to used bulk sweetener. However, all the values were determined below 0.4 which is critical limit for chocolate. Regarding overall acceptability, sugar-free dark chocolates tempered by βv seeds had very close scores compared with conventional one, implying that sugar-free chocolates can be produced by βv crystals with desired quality characteristics similar to conventional samples. Results of this study showed that it is possible to produce sucrose-free dark chocolates by using βV seeds with desired quality similar to chocolate produced by using conventional tempering.
On the Efficiency of Electrochemical Devices from the Perspective of Endoreversible Thermodynamics
Authors: Marsik Frantisek , Weigand Bernhard , Tomas Martin , Tucek Ondrej , Novotny Pavel
Published: September 2019

The current work presents a concept that deals with the production of entropy generated by non-equilibrium processes in consequence of mass and energy transfer. The often used concept of endoreversible thermodynamics is based on the non-realistic conjecture that the entire entropy production is realized at the system boundary. In this contribution, an open system in a thermodynamically non-equilibrium state is assumed. Production of entropy is generated due to non-equilibrium processes accompanied by energy conversion. The steady state of the system is maintained by a negative entropy flux. The conclusions for expansion energy conversion, i. e., thermal machines, confirm the general outcomes of the endoreversible thermodynamics. However, the presented conclusions related to non-expansion energy conversion offer a new perspective on the principle of minimum entropy production and the corresponding stability conditions at steady state. The analysis of the energy conversion in closed cycles is presented for fuel cells, i. e., non-expansion energy conversion. The efficiency of the energy conversion is maximal at zero power output. Moreover, the efficiency of the fuel cells, and consequently the efficiency of all non-expansion energy conversion processes, depends on the load and then the maximal possible efficiency can be determined.
Placental elasticity assessment by point shear wave elastography in pregnancies with intrauterine growth restriction
Authors: Akbas Murat , Koyuncu Faik M. , Artunç-Ulkumen Burcu
Published: September 2019

Background

Placental elasticity varies in different diseases. Our objective was to evaluate placental elasticity using point shear wave elastography (pSWE) in pregnancies with intrauterine growth restriction (IUGR).

Methods

A total of 66 pregnant women with IUGR and 81 healthy pregnant women were enrolled. Placental elasticity was measured using the transabdominal pSWE method. Ten measurements were made, and the mean was accepted as the mean placental elasticity value in each case. The results for IUGR pregnancies and controls were compared.

Results

The mean pSWE values were significantly higher in pregnancies with IUGR, which means that women with IUGR have stiffer placentas (P < 0.001). Furthermore, the pSWE values were significantly and positively correlated with Doppler indices and adverse perinatal outcomes.

Conclusion

The pregnancies with IUGR had stiffer placentas than the healthy controls. The utilization of pSWE for placental elasticity may be useful in the diagnosis and management of IUGR as a supplement to the existing ultrasonography methods.