bluuebunny/crossref_metadata_2025 huggingface dataset:
Hemosuccus Pancreaticus: A Comprehensive Review of Presentation Patterns, Diagnostic Approaches, Therapeutic Strategies, and Clinical Outcomes
Authors: Tarar Zahid Ijaz , Khan Hasan Azeem , Inayat Faisal , Goraya Muhammad Hassan Naeem , Raza Mohsin , Ibrahim Faisal , Akhtar Zahra , Malik Adnan , Davis Ryan M.
Published: January 2022

Hemosuccus pancreaticus is a rare but potentially torrential and life-threatening cause of acute upper gastrointestinal bleeding. It is described as an intermittent hemorrhage from the major duodenal papilla via the main pancreatic duct. Peripancreatic pseudoaneurysm following chronic pancreatitis is a common underlying etiology. However, gastroduodenal artery pseudoaneurysm-related hemosuccus pancreaticus remains exceedingly rare in the etiological spectrum of upper gastrointestinal bleeding. We hereby delineate a rare case of hemosuccus pancreaticus associated with gastroduodenal artery pseudoaneurysm in a patient who initially presented with abdominal pain and hematochezia. He was successfully managed with coil embolization without recurrence or sequelae. Furthermore, we conducted a search of the MEDLINE (PubMed and Ovid) database for relevant studies on hemosuccus pancreaticus published between inception and September 15, 2021. The available clinical evidence on causes, presentation patterns, diagnosis, and management was analyzed and summarized. This article highlights the rarity, the intermittent nature of hemorrhage, and the lack of a standardized diagnostic approach for this elusive disease. Clinicians should remain cognizant of hemosuccus pancreaticus, especially in patients presenting with symptoms and signs of intermittent gastrointestinal bleeding and abdominal pain. Prompt diagnosis carries paramount importance in saving patients from repeat hospital admissions and disease-associated morbidity and mortality. Conventional angiography with coil embolization may constitute an effective treatment strategy.
Designing Online Professional Learning to Support Educators to Teach for Equity During COVID and Black Lives Matter
Authors: Buttimer Christopher J. , Littenberg-Tobias Joshua , Reich Justin
Published: January 2022

The massive racial inequities exposed by the COVID-19 pandemic and the nationwide protests in response to the killings of unarmed Black people forced a reckoning among many educators about racial injustice in the educational system. In March 2020, we launched a massive open online course designed to support teachers in adopting antiracist equity mind-sets and practices. We used a mixed-methods approach to describe how the participants experienced the online course between March and July 2020. Participants in immediate post- and follow-up surveys reported statistically significant shifts in their mind-sets and practices toward equitable teaching practices (effect size = 0.18–58 SD). In interviews, participants described how the course helped them change their practice through acquiring new language, reflecting collaboratively on practice, and engaging in calls to action. The findings provide insight to designers of online professional learning experiences focused on equity and open up new research areas on online professional learning for equity teaching mind-sets and practices.
Predictors of First-Grade Teachers’ Teaching-Related Time During COVID-19
Authors: Johnson Anna D. , Schochet Owen N. , Castle Sherri , Horm Diane , Phillips Deborah A.
Published: January 2022

Exposure to teachers and teaching-related activities is vital for young children’s learning. When COVID-19 closed schools, teachers responded with a mix of live- and prerecorded lessons and one-on-one communication with students, which necessitated shifts in planning time. The current study identifies pre-COVID predictors of time teachers devoted to each of these teaching-related activities to illuminate actionable levers for supporting educators during widespread educational disruption. Teachers with higher prepandemic job commitment devoted more overall time to pandemic-induced remote teaching. Teachers’ prepandemic executive functioning and observed classroom instructional and organizational quality—features of successful teachers during normal times—predicted more during-pandemic time remote teaching, while teacher older age and having more high-needs students was associated with less remote teaching time. These results contribute to an emerging literature that spotlights potential promising avenues for supporting teachers via professional development during normal times as well as in future widespread educational disruptions.
Flavonoid intakes inversely associate with COPD in smokers
Authors: Bondonno Nicola P. , Parmenter Benjamin H. , Dalgaard Frederik , Murray Kevin , Rasmussen Daniel Bech , Kyrø Cecilie , Cassidy Aedin , Bondonno Catherine P. , Lewis Joshua R. , Croft Kevin D. , Gislason Gunnar , Scalbert Augustin , Tjønneland Anne , Overvad Kim , Olsen Anja , Hodgson Jonathan M.
Published: January 2022

Introduction

Higher flavonoid intakes are beneficially associated with pulmonary function parameters; however, their association with chronic obstructive pulmonary disease (COPD) is unknown. This study aimed to examine associations between intakes of 1) total flavonoids, 2) flavonoid subclasses and 3) major flavonoid compounds with incident COPD in participants from the Danish Diet, Cancer and Health study.

Methods

This prospective cohort included 55 413 men and women without COPD, aged 50–65 years at recruitment. Habitual flavonoid intakes at baseline were estimated from a food frequency questionnaire using Phenol-Explorer. Danish nationwide registers were used to identify incident cases of COPD. Associations were modelled using restricted cubic splines within Cox proportional hazards models.

Results

During 23 years of follow-up, 5557 participants were diagnosed with COPD. Of these, 4013 were current smokers, 1062 were former smokers and 482 were never-smokers. After multivariable adjustments, participants with the highest total flavonoid intakes had a 20% lower risk of COPD than those with the lowest intakes (quintile 5versusquintile 1: HR 0.80, 95% CI 0.74–0.87); a 6–22% lower risk was observed for each flavonoid subclass. The inverse association between total flavonoid intake and COPD was present in both men and women but only in current smokers (HR 0.77, 95% CI 0.70–0.84) and former smokers (HR 0.82, 95% CI 0.69–0.97), not never-smokers. Furthermore, higher flavonoid intakes appeared to lessen, but not negate, the higher risk of COPD associated with smoking intensity.

Conclusion

Dietary flavonoids may be important for partially mitigating the risk of smoking-related COPD. However, smoking cessation should remain the highest priority.
Analysis of risk factors for early-onset ventilator-associated pneumonia in a neurosurgical intensive care unit
Authors: Teng Guojie , Wang Ning , Nie Xiuhong , Zhang Lin , Liu Hongjun
Published: January 2022

Background

Ventilator-associated pneumonia (VAP) is a severe infection among patients in the neurosurgery intensive care unit (NICU).

Methods

We retrospectively evaluated risk factors for early-onset ventilator-associated pneumonia (EOVAP) from January 2019 to December 2019 at a NICU. A total of 89 NICU patients who were intubated within 48 h of onset and whose mechanical ventilation time was at least 7 days were enrolled. We evaluated EOVAP that occurred within the first 7 days after the onset of mechanical ventilation. The enrolled patients had no history of chronic lung disease and no clinical manifestations of infection before intubation. Clinical data of patients were recorded, and the incidence of and risk factors for EOVAP were analyzed. Patients were also grouped by age (≥ 65 vs. < 65 years) and whether they had received hypothermia treatment or not.

Results

Among 89 mechanically ventilated patients (49 men and 40 women; the mean age ± SD was 60.1 ± 14.3 years), 40 patients (44.9%) developed EOVAP within 7 days and 14 patients (15.7%) had a multidrug resistant bacterial infection. Binary logistic regression analysis indicated that older age (≥ 65 years) (odds ratio [OR]:3.53, 95% confidence interval [CI]:1.27–9.79, P = 0.015) and therapeutic hypothermia (OR:3.68, CI:1.10–12.31, p = 0.034) were independent predictors of EOVAP. Levels of peripheral blood leukocytes, neutrophils and platelets were lower in the therapeutic hypothermia group than those who did not receive hypothermia treatment.

Conclusions

This study found that older age (≥ 65 years) and therapeutic hypothermia were independently associated with the risk of EOVAP in NICU patients.
Deep learning identified glioblastoma subtypes based on internal genomic expression ranks
Authors: Mao Xing-gang , Xue Xiao-yan , Wang Ling , Lin Wei , Zhang Xiang
Published: January 2022

Background

Glioblastoma (GBM) can be divided into subtypes according to their genomic features, including Proneural (PN), Neural (NE), Classical (CL) and Mesenchymal (ME). However, it is a difficult task to unify various genomic expression profiles which were standardized with various procedures from different studies and to manually classify a given GBM sample into a subtype.

Methods

An algorithm was developed to unify the genomic profiles of GBM samples into a standardized normal distribution (SND), based on their internal expression ranks. Deep neural networks (DNN) and convolutional DNN (CDNN) models were trained on original and SND data. In addition, expanded SND data by combining various The Cancer Genome Atlas (TCGA) datasets were used to improve the robustness and generalization capacity of the CDNN models.

Results

The SND data kept unimodal distribution similar to their original data, and also kept the internal expression ranks of all genes for each sample. CDNN models trained on the SND data showed significantly higher accuracy compared to DNN and CDNN models trained on primary expression data. Interestingly, the CDNN models classified the NE subtype with the lowest accuracy in the GBM datasets, expanded datasets and in IDH wide type GBMs, consistent with the recent studies that NE subtype should be excluded. Furthermore, the CDNN models also recognized independent GBM datasets, even with small set of genomic expressions.

Conclusions

The GBM expression profiles can be transformed into unified SND data, which can be used to train CDNN models with high accuracy and generalization capacity. These models suggested NE subtype may be not compatible with the 4 subtypes classification system.
Effect of perinatal depression on birth and infant health outcomes: a systematic review and meta-analysis of observational studies from Africa
Authors: Dadi Abel Fekadu , Akalu Temesgen Yihunie , Wolde Haileab Fekadu , Baraki Adhanom Gebreegziabher
Published: January 2022

Background

Antenatal depression is associated with intrauterine growth retardation, preterm birth, and low birth weight. Infants born to mothers with postnatal depression also may suffer from malnutrition and other health problems. Even though there are few single studies conducted so far, a systematic review of these studies is highly important to highlight the effect of antenatal and perinatal depression on adverse birth and infant health outcomes in Africa.

Methods

We used the Preferred Report Items for Systematic Review and Meta-analysis (PRISMA) when conducting this study. Databases like CINAHL (EBSCO), MEDLINE (via Ovid and PubMed), PsycINFO, Emcare, Psychiatry Online, and Scopus were searched. In addition, Google Scholar and references from a list of eligible studies were explored. We included good quality observational studies based on Newcastle Ottawa Scale which are published in the English language between 2007 and 2018.  Heterogeneity and publication bias were assessed. Meta-analysis with a random effect model was employed to determine the pooled effect sizes with a 95% confidence interval. The review protocol is registered in PROSPERO (CRD42018106714).

Result

We found three studies (1511 participants) and 11 studies (22,254 participants) conducted on the effect of antenatal depression on birth outcomes and perinatal depression on adverse infant health outcomes, respectively. The overall risk of having adverse birth outcomes was 2.26 (95% CI: 1.43, 3.58) times higher among pregnant mothers with depression. The risk of preterm birth and low birth weight was 1.77 (95% CI: 1.03, 3.04) and 2.98 (95% CI: 1.60, 5.55) respectively. Similarly, the risk of having adverse infant health outcomes namely malnutrition and febrile illness was 1.61 (95% CI: 1.34, 1.95) times higher among mothers who had perinatal depression.

Conclusions

We have found a significant association between antenatal depression and adverse birth outcomes, low birth weight and preterm birth. Similarly, a significant effect of perinatal depression on adverse infant health outcomes namely, malnutrition, and febrile illnesses was observed. The findings highlight that it is time to integrate mental health services with routine maternal health care services to improve birth outcomes and reduce infant morbidity.
Tanshinone IIA attenuates the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis
Authors: Li Xiaoman , Jia Qi , Zhou Yinyin , Jiang Xuan , Song Li , Wu Yuanyuan , Wang Aiyun , Chen Wenxing , Wang Shijun , Lu Yin
Published: January 2022

Background

Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear. This work aims to explore the roles and underlying mechanisms of Tanshinone IIA in breast cancer stemness.

Methods

In vitro mammary spheroid formation, flow cytometry assay on CD24−/CD44+sub-population, ALDH activity detection, cell viability assay and western blot analysis, and in vivo tumor-initiating analysis were performed to examine the effects of Tanshinone IIA on the stemness of breast cancer cells. MiRNAs-based transcriptome sequencing and data analysis, online dataset analysis, luciferase reporter assay combined with rescuing experiments were constructed to explore the underlying mechanisms.

Results

Tanshinone IIA attenuated the stemness of breast cancer cells, evident by downregulating the expression of stemness markers, hindering the capacity of spheroid formation, decreasing the CD24−/CD44+sub-population in a concentration-dependent manner and reducing the tumor-initiating ability of breast cancer cells. Additionally, Tanshinone IIA enhanced adriamycin sensitivity and attenuated adriamycin resistance of breast cancer cells. Combined with miRNAs-based transcriptome sequencing assay, it was found that Tanshinone IIA downregulated miR-125b level and upregulated its target gene STARD13 (StAR-related lipid transfer protein 13) level, thus inactivating the miR-125b/STARD13 axis, which had been previously confirmed to promote breast cancer progression. Notably, miR-125b overexpression enhanced the stemness of breast cancer cells, and miR-125b overexpression or STARD13 knockdown impaired the inhibitory effects of Tanshinone IIA on the stemness of breast cancer cells.

Conclusions

Tanshinone IIA could attenuate the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis.
SLC3A2 inhibits ferroptosis in laryngeal carcinoma via mTOR pathway
Authors: Wu Fangxing , Xiong Gaoyun , Chen Zejun , Lei Chenyang , Liu Qianqian , Bai Yundan
Published: January 2022

Objective

This study aimed to explore the mRNA and protein expression of SLC3A2 in laryngeal carcinoma cells and tissues, and functional regulatory mechanism of SLC3A2 in cell ferroptosis of laryngeal carcinoma.

Methods

We chose the key gene-SLC3A2 of DEGs from TCGA by bioinformatics analysis, and then we constructed stable knockdown of SLC3A2 in laryngeal carcinoma cells. MTT assay and clonogenic assay were used to determine cell viability and cell growth, respectively. The mRNA and protein expression were determined by RT-qPCR and western blotting, respectively. Xenograft tumor model was used to determine the role of SLC3A2 in tumor growth.

Results

The results of limma analysis recovered that 92 genes were involved in both upregulated DEGs and high risk of poor prognosis, whereas 36 genes were involved in both downregulated DEGs and low risk of poor prognosis. Pathway enrichment analysis indicated that mTOR signaling pathway and ferroptosis exerted a role in regulating these intersection genes. Moreover, SLC3A2 is a key gene in ferroptosis in laryngeal carcinoma. SLC3A2 is highly expressed in laryngeal carcinoma tissues and cells. Patients with high SLC3A2 expression exerted poor survival. SLC3A2 deficiency inhibited cell proliferation and foci formation. Furthermore, knockdown of SLC3A2 expression induced the efficacy of ferroptosis and suppressed ferroptosis related proteins expression. Mechanically, SLC3A2 deficiency facilitated ferroptosis through upregulating the expression of mTOR and P70S6K, whereas inhibited p-mTOR and p-P70S6K expression in laryngeal carcinoma cells. SLC3A2 deficiency inhibited tumorigenesis in nude mice.

Conclusion

Our study suggests that SLC3A2 negatively regulates ferroptosis through mTOR pathway in laryngeal carcinoma.
Writing Travel as Janus: Cultural Translation as Descriptive Category for Travel Writing
Authors: Wu Shang
Published: January 2022

Abstract: The intersection of the study of travel writing and the study of translation produces two major perspectives: travel writing in translation and translation in travel writing. The first one looks into how the travel narrative is reshaped in a different linguistic and cultural context; the other looks into the translational character of the travel narrative, as the traveller is constantly moving between languages and cultures. Though the conceptual analogy between traveller and translator has been long noted, the linguistic dimension that marks the language difference in travel narrative is rarely underlined. In this essay, in order to explore the possibility of foregrounding both the conceptual link between travel and translation and the linguistic dimension of travel narrative, I propose to integrate an attention to language difference into a reinvention of the contested yet promising term ‘cultural translation’. The American writer Peter Hessler’s travel account Country Driving is cited as a case study.
Naród jako (nie)możliwość polityczna rekonstrukcja ideologii narodu i państwa Jana Rompskiego
Authors: Jabłoński Artur
Published: January 2022

Artykuł jest próba rekonstrukcji wyobrażenia narodu Jana Rompskiego (1913–1969) – kaszubskiego pisarza, współtwórcy ideowo-literackiej grupy Zrzeszyńców. Wizja narodu kaszubskiego J. Rompskiego skonstruowana jest w relacji do narodu i państwa polskiego. Ta idea przez długi czas organizowała dyskurs polityczny Zrzeszyńców i samego Jana Rompskiego, który z czasem stał się najważniejszym ideologiem grupy. Pisarz w swym politycznym projekcie o narodzie kaszubskim podkreślał, że identyfikacja narodowa może ulegać zmianom, jednak zawsze charakteryzuje się symboliką, która pozwala narodowi zdefiniować siebie. Zrzeszyńcy do tej symboliki wprowadzili obywatelskość. W ideologii Jana Rompskiego i Zrzeszyńców oznacza to podmiotowe zaangażowanie się Kaszubów równolegle w sprawy własnej wspólnoty narodowej i państwa polskiego.
Edukacja kaszubska: 30 lat minęło i co dalej?
Authors: Kożyczkowska Adela
Published: January 2022

Edukacja kaszubska różni się od tradycyjnie pojmowanej i realizowanej edukacji regionalnej, choć wielu nauczycieli nadal realizuje nauczanie języka i kultury kaszubskiej w podejściu typowym dla edukacji regionalnej. W przypadku kaszubskim jest to przede wszystkim przesunięcie w obszar kultury ludowej i niekrytyczne budowanie przeświadczenia, że jeśli mamy do czynienia z kaszubszczyzną to muszą temu towarzyszyć estradowe stroje ludowe, tańce i przyśpiewki. Jednak Kaszubi – zwłaszcza młodzi – jakby na przekór takim tendencjom, zaczynają częściej artykułować swoje potrzeby kulturowe (w tym językowe) jako element codzienności, w tym także potrzeby związananej z aktywnością twórczą. Wymusza to zatem zmiany w samym systemie edukacji kaszubskiej. Niniejszy artykuł jest przeglądem aktualnego stanu edukacji kaszubskiej w obszarach dla niej ważnych, jak teoria i szkolna realizacja (co przekłada się na liczbę uczniów czy dostępność podręczników). Jest to pedagogiczna refleksja na temat edukacji języka i kultury kaszubskiej oraz leżącej u podstaw kaszubskiej polityki tożsamości.
„Uważnić”* głos dzieci i młodzieży ze środowisk przymusowych migrantów. Wybrane aspekty etyczne i metodologiczne badania doświadczeń udziału w szkolnej edukacji
Authors: Młynarczuk-Sokołowska Anna
Published: January 2022

Szkoła jest rzeczywistością, która skupia społeczne światy uczniów, nauczycieli, a także innych osób konstruujących jej codzienność. Dzieci i młodzież ze środowisk przymusowych migrantów od lat stanowią część polskiego systemu edukacji. Uczestnictwo w edukacji jest dużym wyzwaniem dla tej grupy uczniów w związku z trudnymi doświadczeniami z kraju pochodzenia, barierą językową, różnicami kulturowymi itd. Tekst poświęcony jest uprawomocnianiu głosu dzieci i młodzieży z doświadczeniem uchodźstwa w toku procesu badawczego w celu projektowania/wprowadzania zmian w pracy szkoły. Artykuł złożony jest z trzech części. Pierwsza dotyczy głównych problemów edukacyjnych oraz badawczych związanych z funkcjonowaniem tej grupy uczniów w polskiej szkole. W drugiej analizie została poddana kwestia zasadności prowadzenia badań wśród dzieci i młodzieży ze środowisk przymusowych migrantów. Ostatnia prezentuje jedną z wielu ścieżek uprawomocniania głosu dzieci i młodzieży z doświadczeniem przymusowej migracji. Dotyczy ona analizy narracji tej grupy uczniów na temat uczestnictwa w szkolnej edukacji z perspektywy autobiograficznej, z uwzględnieniem podejścia partycypacyjnego.
RESEARCH ON THE QUALITY OF UNIVERSITY CLASSES IN THE CONTEXT OF THEIR CLIMATE
Authors: Sobczak Sławomir , Zacharuk Tamara
Published: January 2022

The transmission of knowledge is not merely the selection of appropria te teaching methods; it is also influenced by personal interactions. This study explored the influence of student-teacher interpersonal relationships and the influence of these interactions on students’ opinions of the quality of education. The primary objective was to understand aspects that compel a student to attend classes taught by a particular teacher. The study acquired data on 540 students and 270 lecturers. It hypothesized that the higher the degree of positive student-teacher interactions, the higher the students’ evaluation of class quality. The correlation was found to be positive and statistically significant at 0.01 level (Pearson’s correlation coefficient of 0.636)
KOMPARATYSTYKA EDUKACYJNA W PERSPEKTYWIE FILOZOFICZNEJ: SERGIUSZ HESSEN (1887–1950) I JEGO PODEJŚCIE DO BADAŃ PORÓWNAWCZYCH W PEDAGOGICE
Authors: Wojniak Justyna
Published: January 2022

Sergiusz Hessen, filozof i pedagog, to postać, która zajmuje ugruntowane miejsce w historii myśli pedagogicznej, a centralnym punktem jego twórczości stała się koncepcja naukowego statusu pedagogiki jako filozofii stosowanej. Celem artykułu jest przybliżenie innego, istotnego obszaru zainteresowań badawczych tego uczonego, jaki stanowiła komparatystyka edukacyjna. Wydaje się to uzasadnione o tyle, że dorobek tego uczonego z zakresu badań porównawczych jest nakreślony w dość ogólny sposób lub jedynie zasygnalizowany. We wprowadzeniu do artykułu zaprezentowano krótki zarys biografii Hessena, ważny z punktu widzenia badań, jakie prowadził. W dalszej części znajduje się charakterystyka jego koncepcji pedagogiki jako filozofii stosowanej, a następnie uwaga została skoncentrowana na prowadzonych przez tego uczonego badaniach z obszaru komparatystyki pedagogicznej. Zastosowana na potrzeby artykułu analiza treści prac Hessena o charakterze porównawczym oraz dostępnych materiałów wskazujących na ich międzynarodowy odbiór, pozwalają na sformułowanie wniosku, że w osobie Sergiusza Hessena mamy do czynienia z jednym z pierwszych w Europie uczonych, który sposób systematyczny prowadził badania porównawcze systemów edukacyjnych, a jego prace wraz z dorobkiem Józefa Chałasińskiego, Zygmunta Mysłakowskiego czy Bogdana Nawroczyńskiego tworzyły zręby polskiej komparatystyki edukacyjnej.
Stosunki władzy na linii Smetona–Voldemaras. Rola organizacji Żelaznego Wilka w litewskim systemie politycznym
Authors: Malužinas Martinas
Published: January 2022

Podejmując problematykę rozwoju i roli stosunków między Antanasem Smetoną a Augustinasem Voldemarasem oraz grup ich zwolenników w litewskim systemie politycznym w latach 1926–1940, należy wskazać podstawowe elementy, które przyczyniły się do wywołania konfliktu pomiędzy dwoma przywódcami Związku Narodowców, a mianowicie znaczenie tajnych organizacji paramilitarnych (takich jak Żelazny Wilk) w reżimie Smetony i Voldemarasa, kwestię ideologii i myśli politycznej oraz politykę wewnętrzną wobec mniejszości narodowych na Litwie. Zakres przedmiotowy artykułu wytycza konflikt w łonie partii rządzącej. Zakres podmiotowy natomiast odnosi się do prezydenta Republiki Litewskiej Antanasa Smetony, premiera Augustinasa Voldemarasa oraz działalności organizacji voldemarystów. Zakres terytorialny obejmuje ziemie litewskie oraz obszary będące pod administracją litewską (m.in. obszar Kłajpedy). Ramy chronologiczne pola badawczego wyznaczają lata 1926–1940.
Burmistrz Słupska Fryderyk Pałubicki i jego wkład w sporządzenie przeróbki atlasowej wersji mapy Pomorza Eilharda Lubinusa
Authors: Pałubicki Roch
Published: January 2022

Celem artykułu jest omówienie okoliczności i czasu powstania znanej siedemnastowiecznej przeróbki mapy Księstwa Pomorskiego, a także jej źródeł kartograficznych i roli, jaką odegrała w kartografii pomorskiej. Do tej pory osoba wskazana na mapie jako Frid. Palbitzke nie była zidentyfikowana. Artykuł omawia jej tożsamość, wkład w opracowanie przeróbki mapy oraz cel jej sporządzenia.
Cuerpo y escritura. Los glifos fotográficos de Leandro Katz
Authors: González Carina
Published: January 2022

Durante el siglo xx, los estudios sobre el cuerpo han adquirido un matiz filosófico que lo cuestionan como territorio de la identidad. Desde esta perspectiva el cuerpo es una construcción simbólica que se crea más allá de lo material, en donde intervienen distintos sistemas de representación. Este trabajo analiza una instalación de Leandro Katz (1938) en la que el artista explora la relación particular entre cuerpo, muerte y fotografía. A partir de la intervención de la imagen por lo textual, se examinan las formas en las que el cuerpo produce y recupera sentidos para hacer consciente su propia potencialidad.
261. Cambio climático y gestión del riesgo en el proceso de ordenamiento territorial en Perú
Authors: Rendón-Cusi Sisko Fernando
Published: January 2022

Actualmente el mundo se enfrenta a un gran desafío en un escenario de inminente aceleración del cambio climático. Según las previsiones, el Perú se encuentra entre los países más vulnerables frente a este problema. Este estudio tiene como objetivo revisar el proceso de iniciativas nacionales enfocadas en la reducción de los impactos del cambio climático. La metodología de estudio consistió en la revisión de las directrices del Plan de Ordenamiento Territorial (POT) y los elementos que lo articulan con las iniciativas de mitigación del cambio climático y gestión de riesgo en el Perú. Del análisis, se observa que existe dispersión de acciones en las diferentes administraciones públicas, ineficiencia en la gestión de los recursos disponibles, burocratización de los procesos, escasa claridad en los objetivos, exiguo interés de los decisores políticos y reducida consciencia de la población frente al problema.
Predicting singleton antepartum stillbirth by the demographic Fetal Medicine Foundation Risk Calculator—A retrospective case-control study
Authors: Muin Dana A. , Windsperger Karin , Attia Nadia , Kiss Herbert
Published: January 2022

Objective

To assess the risk of singleton intrauterine fetal death (IUFD) in women by the demographic setting of the online Fetal Medicine Foundation (FMF) Stillbirth Risk Calculator.

Methods

Retrospective single-centre case-control study involving 144 women having suffered IUFD and 247 women after delivery of a live-born singleton. Nonparametric receiver operating characteristics (ROC) analyses were performed to predict the prognostic power of the FMF Stillbirth risk score and to generate a cut-off value to discriminate best between the event of IUFD versus live birth.

Results

Women in the IUFD cohort born a significantly higher overall risk with a median FMF risk score of 0.45% (IQR 0.23–0.99) compared to controls [0.23% (IQR 0.21–0.29); p<0.001]. Demographic factors contributing to an increased risk of IUFD in our cohort were maternal obesity (p = 0.002), smoking (p<0.001), chronic hypertension (p = 0.015), antiphospholipid syndrome (p = 0.017), type 2 diabetes (p<0.001), and insulin requirement (p<0.001). ROC analyses showed an area under the curve (AUC) of 0.72 (95% CI 0.67–0.78; p<0.001) for predicting overall IUFD and an AUC of 0.72 (95% CI 0.64–0.80; p<0.001), respectively, for predicting IUFD excluding congenital malformations. The FMF risk score at a cut-off of 0.34% (OR 6.22; 95% CI 3.91–9.89; p<0.001) yielded an 82% specificity and 58% sensitivity in predicting IUFD with a positive and negative predictive value of 0.94% and 99.84%, respectively.

Conclusion

The FMF Stillbirth Risk Calculator based upon maternal demographic and obstetric characteristics only may help identify women at low risk of antepartum stillbirth.
Dynamic performance–Energy tradeoff consolidation with contention-aware resource provisioning in containerized clouds
Authors: Canosa-Reyes Rewer M. , Tchernykh Andrei , Cortés-Mendoza Jorge M. , Pulido-Gaytan Bernardo , Rivera-Rodriguez Raúl , Lozano-Rizk Jose E. , Concepción-Morales Eduardo R. , Castro Barrera Harold Enrique , Barrios-Hernandez Carlos J. , Medrano-Jaimes Favio , Avetisyan Arutyun , Babenko Mikhail , Drozdov Alexander Yu.
Published: January 2022

Containers have emerged as a more portable and efficient solution than virtual machines for cloud infrastructure providing both a flexible way to build and deploy applications. The quality of service, security, performance, energy consumption, among others, are essential aspects of their deployment, management, and orchestration. Inappropriate resource allocation can lead to resource contention, entailing reduced performance, poor energy efficiency, and other potentially damaging effects. In this paper, we present a set of online job allocation strategies to optimize quality of service, energy savings, and completion time, considering contention for shared on-chip resources. We consider the job allocation as the multilevel dynamic bin-packing problem that provides a lightweight runtime solution that minimizes contention and energy consumption while maximizing utilization. The proposed strategies are based on two and three levels of scheduling policies with container selection, capacity distribution, and contention-aware allocation. The energy model considers joint execution of applications of different types on shared resources generalized by the job concentration paradigm. We provide an experimental analysis of eighty-six scheduling heuristics with scientific workloads of memory and CPU-intensive jobs. The proposed techniques outperform classical solutions in terms of quality of service, energy savings, and completion time by 21.73–43.44%, 44.06–92.11%, and 16.38–24.17%, respectively, leading to a cost-efficient resource allocation for cloud infrastructures.
Spatializing material–corporeal entanglements: A new materialist approach to the agential work of costume in the stage adaptation of The Lovely Bones (2018)
Authors: Gurnos-Davies Kitty
Published: January 2022

This article argues for the value of conceptualizing the agency of costume in performance when it is not worn directly upon the body. I employ a new materialist framework to examine the spatial dynamics of the shifting corporeal–material relations established when costume is set apart from an actor onstage and, unworn, asserts its agency as an independent force distinct from the performer. My investigation is supported by a close analysis of Bryony Lavery’s page-to-stage adaptation of Alice Sebold’s novel, The Lovely Bones (2002), directed by Melly Still and performed at the Royal & Derngate, Northampton in 2018. Drawing upon the observation of rehearsals and performances encountered as an embedded researcher, my discussion centres on the live practices of theatrical production. Employing Bennett’s new materialist thinking laid out in Vibrant Matter: A Political Ecology of Things (2010) and Bill Brown’s ‘Thing Theory’ (2001, 2015), my discussion of The Lovely Bones shows costume to be an active participant in a ‘distributive agency’ enacted between garment and performer, the contours of which are amplified when the two are set apart. The spatial disentanglement of the material and corporeal, evidenced in the performance of costume in The Lovely Bones, thus provides an opportunity to present a fuller understanding of the material agency of the stage.
Fraying Parachutes: Costume agency and convivencia in contemporary circus performance making
Authors: Man Michelle
Published: January 2022

Fraying Parachutes explores from a choreographer/facilitator’s perspective the agency found in the costume making processes during Femme de Feu’s Circus Sessions 2019, in which three abandoned parachutes were upcycled and transformed into circus costumes. It traces the journey from conceptualization to ad hoc design, involving de-construction and much physical entanglement, to the eventual wear and non-wearability of the costumes in performance. Bringing together fourteen artists from South America, North America and Europe, the embodied research that informed this work took as its foci: positive receptivity, hospitality and fascination as qualities and modes of creating collectively. The experimental circus costume making processes provided an opportunity to physically expand upon theories of agential realism and entanglement, in relation to the material and the social. The re-purposed parachutes served as constant reminders of flight, suspension, risk and rescue, qualities that are innately present in circus technique and performance. In ‘rescuing’ the parachutes from landfill, the work also gave visibility to an ecological ethic in performance making, or what Tanja Beer refers to as a practice of ecoscenography, where issues of waste and sustainability may be addressed. Underscoring this essay will be the notion of convivencia or a literal ‘living with’ other and the non-human as essential to process and performance. Distinct to a co-labouring of ideas, in Circus Sessions, convivencia encompassed our creative entanglements, the friction and flow in artistic decision making, our discussions, reflections and laughter. It would also attune our listening to epistemologies of the South, to the diverse cultural perspectives and sensibilities that the different performers from three continents brought to the project. In this visual essay, costume agency is understood as a tensile potentiality that generates creative energy informed by the serendipitous opportunities found in the sensory binding of costume making processes.
Lendo Habermas com Habermas
Authors: Marques Ângela Cristina Salgueiro , Martino Luís Mauro Sá
Published: January 2022

Como um autor lê sua própria obra décadas após sua publicação? Esta questão é particularmente importante quando se leva em conta que a obra em questão, Mudança Estrutural da Esfera Pública, tornou-se um marco nos estudos de Comunicação Política desde sua primeira publicação em 1962. Este artigo analisa o prefácio do autor à edição de 1990, no qual faz uma extensa revisão e crítica da obra, destacando quatro aspectos: (1) as diferenças do ambiente midiático de 1962, 1990 e hoje; (2) a ambivalência da “esfera pública” como um conceito em cada caso; (3) a tensão entre a comunicação da mídia e a conversa pessoal que permeia o conceito; (4) a problematização da diferença e das assimetrias de poder na constituição da esfera pública. Esses elementos são analisados no contexto de estudos críticos da obra.
Anthelmintic resistance status of goat gastrointestinal nematodes in Sing Buri Province, Thailand
Authors: Ratanapob Niorn , Thuamsuwan Nattanan , Thongyuan Suporn
Published: January 2022

Background and Aim: Promotions of goat farming by both public and private sectors encouraged considerable goat raising in central Thailand. Gastrointestinal nematodes (GIN) infection is a major health and economic problem; however, evidence of resistance to broad-spectrum anthelmintics is frequently reported. Investigation of anthelmintic resistance (AR) status and identification of factors related to the development of AR is important components for sustainable GIN control. However, no information is available on this topic in the study area. The present study aimed to gather information on GIN control practices and to evaluate the effectiveness of albendazole, ivermectin, and levamisole for treating GIN infestation in goat herds in Sing Buri Province. Materials and Methods: Twenty-nine herds were randomly selected. Information on management practices was collected by face-to-face interview using a structured questionnaire. Three field experiments for routinely used anthelmintics, including albendazole, ivermectin, and levamisole were conducted from June 2019 to November 2019. Fecal samples were collected pre- and post-treatment and examined for fecal egg count reduction to determine the status of anthelmintic resistance of goat GIN. Results: Several improper practices were identified that lead to AR, especially chronic use of albendazole and ivermectin. All herds were considered resistant to albendazole and ivermectin, and levamisole resistant nematodes were detected in two herds. AR was strongly linked with the continuous use of anthelmintics. Conclusion: Levamisole, which was still effective in the province, should be used with caution to minimize the selection of resistant strains. Farmers should be provided with updated information for sustainable parasite control. Further, the efficacy of anthelmintics should be routinely monitored.
E-Extensión universitaria, una herramienta para difundir el modelo acuapónico para contribuir a la innovación en la producción de alimentos orgánicos, con baja huella de carbono y agua
Authors: Scaglione María Cristina , Delmar Cerutti Raúl
Published: January 2022

University e-Extension plays a preponderant role in the diffusion and adoption of new food production technologies. The increasing demands of a growing world population are putting increasing pressure on water resources, land use, and ecosystems globally. To promote comprehensive, highly sustainable, and innovative solutions, we chose aquaponics as a model and for the dissemination of ICTs to teachers, students, and family producers. The intensive use of ICTs made it possible to carry out actions remotely and in real time, monitor specific situations, and produce permanent changes in behaviors and activities. The interaction between people from different social and geographical spaces was achieved, linking their cultural realities, and leaving behind the barriers of time and space. In the framework of this new culture, e-Extension has great opportunities to make the most of instruments that enhance the work of extensionists.
Matem-SRB: resultados de su primer año de implementación
Authors: Espinoza González Johan , Hernández Vargas Fabián
Published: January 2022

MATEM-SRB is a project that combines extension, teaching, and research; it is based on the principle of regionalization and social action. It offers Mathematics teachers the opportunity to train in different subjects; it also allows secondary school students the opportunity to receive a comprehensive mathematics education, helping them increase their knowledge levels in the discipline and allowing them to interact with the university environment. MATEM-SRB integrates the participation of different actors, such as Universidad Nacional de Costa Rica (UNA), Brunca Regional Campus, the UNA School of Mathematics, participating institutions, and tutors. This situation promotes constant collaboration in search of providing students living in some country’s least developed areas with new opportunities for academic and personal growth.
Aportes del trabajo colaborativo interinstitucional en procesos de extensión para la transformación social: caso Ugrosanta
Authors: Vargas Venegas Marta , Ávila Artavia Alejandra , Mena García Priscilla
Published: January 2022

This work is carried out by the School of Planning and Social Promotion, which is part of the Faculty of Social Sciences of the National University of Costa Rica (UNA). This academic unit was created in 1974; it has been characterized by integrating extension practices in teaching processes and promoting the active participation in students, academic teams, communities, and institutions through collaborative work that seeks the interaction between different social actors in favor of social transformation.This article presents the results of a 3-year collaborative work, developed in the community of Santa Cruz de Turrialba, Costa Rica, in coordination with the National System of Conservation Areas (SINAC), the organization Unión de Agrupaciones de Santa Cruz de Turrialba (UGROSANTA), fifteen students, and two teachers from the School of Planning and Social Promotion (EPPS) of the National University. In addition, the project had the participation of the Ministry of Culture and Youth of Costa Rica.First, key concepts for this analysis are highlighted, such as collaborative work, university extension, and rural development with a territorial approach as a basis for social transformation. Subsequently, the case study and the methodology used to write this article are contextualized. Finally, the results of the interviews conducted and the academic reflections generated by the development of the university-society relationship through collaborative work are presented.
Sacrificios humanos en santuarios de altura en la región de Arequipa
Authors: Morales Galarza Marco Antonio
Published: January 2022

Según Pearson (2008), el sacrificio humano puede ser considerado como el último intercambio recíproco o como la sumisión de los vivos a lo sobrenatural, que se expresa mediante el regalo o tributo que se les entrega a los dioses, que consiste en entregar lo más preciado para el ser humano, que sería la vida humana. Sin embargo, como señala Pearson (2008) el concepto de sacrificio humano es difícil de definir o identificar, precisamente porque puede haber una delgada línea que lo separa o distingue de la ejecución o exterminio de rivales o prisioneros de guerra o del autosacrificio altruista. Como indica Pearson, generalmente el sacrificio humano está dirigido a entidades sobrenaturales y es llevado a cabo bajo los auspicios de especialistas en rituales. Lo señalado por Pearson se ve plasmado en los sacrificios realizados por los incas en los santuarios de altura, en volcanes de la región de Arequipa como el Misti, Picchu Picchu, Chachani, Ampato, Sara Sara.
Cerro respiro y la administración inca en el valle bajo del Chillón
Authors: Ayala Castillo Gil Ronal
Published: January 2022

El presente artículo es resultado de las investigaciones realizadas en el sitio Cerro Respiro ubicado en la margen derecha del valle bajo del Chillón, muy próximo a la desembocadura el río Chillón. Los trabajos llevados en el sitio tuvo como corolario dar una explicación sobre su cronología y funcionalidad del sitio relacionado de manera directa con la organización político-administrativo a partir de los edificios definidos como residencias de elite y los espacios públicos, cuyas características arquitectónicas la definen como tal, donde los contextos excavados y las evidencias culturales fueron definidas al periodo Intermedio Tardío y Horizonte Tardío, las cuales sirven de sustento al problema planteado. El sitio es explicado en base a un análisis arquitectónico comparativo de tres asentamientos que comparten construcciones residenciales de élite y habrían desempeñado esta misma función en el valle del Chillón. Este tipo de instalaciones incas habrían sido el resultado del proceso de conquista de manera directa, estrategia llevada a cabo por el estado inca, con el afán de controlar recursos humanos, agrícolas y naturales desde los palacios o residencias de élite ubicados en puntos estra tégicos del valle bajo del Chillón, articulados a una red de caminos de las cuales aún quedan evidencias.
Lockdown como medida de intervenção para mitigar a propagação da COVID-19: um estudo de modelagem
Authors: Santana-Santos Eduesley , Gois Aédson Nascimento , Laureano Estêvão Esmi , Santos David da Silva , Santos Luiz Fernando Souza , Sánchez Daniel Eduardo , Vieira Rita de Cássia Almeida , Oliveira Jussiely Cunha
Published: January 2022

Introdução: Este trabalho visa desenvolver um modelo biomatemático de transmissão da COVID-19, no estado de Sergipe, Brasil, a fim de estimar a distribuição dos casos ao longo do tempo e projetar o impacto na propagação do surto epidêmico devido às intervenções e medidas de controle sobre a população local. Métodos: Estudo de modelagem matemática epidemiológica, realizado para analisar a dinâmica dos casos acumulados de COVID-19, que utilizou um modelo de crescimento logístico que adiciona um termo de retirada de indivíduos como medida de controle. Foram simulados três possíveis cenários de propagação da COVID-19 baseados em três diferentes taxas de retirada de indivíduos. Cada uma das taxas é ajustada com dados reais sobre número de infetados e as medidas de controle sobre a população.  Resultados: A medida extrema de isolamento total, ou lockdown, seria o melhor cenário, apresentando menor incidência de infectados, quando comparado às demais medidas. O número de infectados cresceria vagarosamente ao longo dos meses e o número de indivíduos sintomáticos nesse cenário seria de 40.265 casos. Percebeu-se que o Estado de Sergipe ainda encontra-se na fase inicial da doença, em quaisquer dos cenários. Foi possível observar que o pico dos casos e o equilíbrio, no cenário atual de isolamento social, se darão quando atingir a nova capacidade suporte, ao final de agosto em aproximadamente 1.171.353 indivíduos infectados. Conclusão: Percebeu-se que o lockdown é a intervenção com maior capacidade de mitigação da propagação do vírus pela população.
[RETRACTED] Boulder Highlands CBD Gummies – SCAM ALERT? Update 2022 v1
Authors: Highlands CBD Gummies Boulder
Published: January 2022

[RETRACTED]

At this time a lot of people are impacted by physical and mental disturbances such as joint pain, inflammation, chronic pain, stress, anxiety, and other problems. Due to the pandemic, people are not alert about their fitness and they are trying a lot of new and advanced methods to improve their stamina.
Wie bekommt Industrie 4.0 Bedeutung?
Authors: Fay Alexander , Diedrich Christian , Thron Mario , Scholz André , Schmidt Philipp Puntel , Ladiges Jan , Holm Thomas
Published: January 2022

Dieser Beitrag zeigt auf, wie in Deutschland erarbeitete Standards zur Beschreibung mit Merkmalen (insbesondere eClass) in Kombination mit weiteren Normen und Standards eine semantische Basis für den Informationsaustausch in den Anwendungsfällen von Industrie 4.0 bilden können. Der Beitrag möchte die Nutzung deutscher Standards und Normen im Kontext von Industrie 4.0 unterstützen und damit eine verlässliche Basis für Investitionen der Wirtschaft in Produkte und Prozesse schaffen.