bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGEMBANGAN MODUL PEMBELAJARAN FISIKA SMA BERBASIS PEMECAHAN MASALAH KONSEP TEGANGAN PERMUKAAN DAN VISKOSITAS
Authors: Carlina Nova , Putri Desy Hanisa , Medriati Rosane
Published: July 2024

ABSTRAK Penelitian ini bertujuan untuk mendeskripsikan hasil kelayakan dan menghasilkan karakteristik modul pembelajaram fisika berbasis pemecahan masalah. Metode penelitian  R&D dengan model 3D yang terdiri dari tiga tahap yaitu pendefinisian (observasi, studi literatur, analisis kebutuhan, dan analisis bahan ajar), perancangan (validasi desain dan revisi desain ) dan pengembangan (validasi modul dan revisi modul) oleh Thiagrajan (1974). Instrumen yang digunakan dalam penelitian ini yaitu lembar observasi, lembar angket guru dan siswa, lembar penilaian ahli. Hasil penelitian menunjukkan bahwa modul fisika berbasis pemecahan masalah yang dikembangkan  termasuk dalam  kategori cukup valid dengan aspek isi 71%, aspek penyajian sebesar 75%, aspek bahasa sebesar 75% dan aspek pemecahan masalah sebesar 71% serta kegrafikan sebesar 75% memiliki kriteria cukup valid. Kata Kunci: modul pembelajaran, pemecahan masalah, tegangan permukaan dan viskositas ABSTRACT This research aimed to describe the feasibility results and produce characteristics of high school physics learning modules based on problem solving. The method is R&D with a 3D model consisting of 3 stages is definition (observation, study of literature, analysis of needs, and analysis of teaching material),  design (design validation and design revision) and develop (module validation and module revision)  by Thiagrajan (1974). The instruments used in this study were the observation sheet, students and teacher questionnaire sheet, questionnaire test validation team of experts. The results showed that the physics modules developed with problem solving were included in the enough valid category on the content aspect of 71%, the presentation aspect by 75%, the language aspect by 75% and the problem solving aspect by 71% and the graphics by 75% have quite valid criteria. Keywords: Learning Module, Problem Solving, Surface Tension And Viscosity
PENGEMBANGAN ALAT PERAGA PADA MATERI ENERGI DENGAN MENGGUNAKAN SOLAR CELL, SENSOR ULTRASONIK DAN LIGHT DEPENDENT RESISTOR BERBASIS ARDUINO UNO
Authors: Verawati Yuni , Hamdani Dedy , Setiawan Iwan
Published: July 2024

ABSTRAK Penelitian ini bertujuan untuk menghasilkan produk berupa alat peraga berbasis Arduino Uno pada materi sumber-sumber energi kelas XII yang valid, serta untuk mengetahui tanggapan guru mengenai alat peraga berbasis Arduino Uno. Penelitian ini merupakan jenis penelitian pengembangan (Research and Development) dengan model pengembangan yang digunakan yaitu Pengembangan 4D, yaitu Define, Design, Develop dan Dissemination yang disesuaikan. Validasi desain dilakukan oleh 3 judgement ahli untuk menilai produk yang dikembangkan dari aspek kesesuaian, kemenarikan, ketahanan, keakuratan, efektif alat, komponen kelayakan isi dan komponen teknis. Hasil uji validitas mendapatkan hasil rata-rata sebesar 92,7% dengan kategori sangat layak. Berdasarkan hasil tersebut, dapat disimpulkan bahwa alat peraga berbasis Arduino Uno pada materi sumber-sumber energi yang dikembangkan sudah valid dan teruji. Respons tanggapan yang diberikan guru mendapatkan hasil rata-rata 87,89% dengan kategori sangat baik. Sehingga alat peraga berbasis Arduino Uno dapat dijadikan alat peraga tambahan dalam membantu guru memberikan pemahaman materi kepada siswa pada saat proses pembelajaran. Kata  kunci:  Penelitian Pengembangan, Alat Peraga, Arduino Uno ABSTRACT This study aims to produce a product in the form of teaching aids based on Arduino Uno on valid class XII energy sources, as well as to find out the teacher's response to teaching aids based on Arduino Uno. This research is a type of research and development with the development model used, namely 4D Development, namely Define, Design, Develop and Dissemination which is adjusted. Design validation is carried out by 3 expert judgments to assess the developed product from the aspects of suitability, attractiveness, durability, accuracy, tool effectiveness, content feasibility components and technical components. The results of the validity test get an average result of 92.7% with the very feasible category. Based on these results, it can be concluded that the Arduino Uno-based teaching aids on the energy sources developed are valid and tested. The responses given by the teacher got an average result of 87.89% with a very good category. So that Arduino Uno-based teaching aids can be used as additional teaching aids in helping teachers provide understanding of the material to students during the learning process. Keywords: Research Development, Teaching Aid, Arduino Uno
PENGEMBANGAN PEMBELAJARAN DARING BERBASIS MOOCs UNTUK MENINGKATKAN MOTIVASI BELAJAR SISWA PADA MATERI SUHU DAN KALOR
Authors: Oksatianti Bebby Rino , Risdianto Eko , Mayub Afrizal
Published: July 2024

ABSTRAK Penelitian ini bertujuan untuk mendeskripsikan kelayakan dan karakteristik pembelajaran daring berbasis MOOCs untuk meningkatkan motivasi belajar siswa pada materi suhu dan kalor serta mendapatkan persepsi dari peserta didik yang baik. Penelitian ini merupakan penelitian dan pengembangan (R&D) dengan model 4D dengan langkah-langkah define, design ,development dan dissemination. Teknik pengumpulan data yaitu teknik non tes dimana menggunakan data observasi dan angket. Teknik analisis data menggunakan metode deskriptif, kualitatif dan kualitatif. Subjek yang digunakan pada penelitian ini adalah guru fisika dan peserta didik kelas XI di SMA Negeri 1 Kota Bengkulu, SMA Negeri 6 Kota Bengkulu dan SMA Negeri 9 Kota Bengkulu. Hasil dari penelitian ini dapat disimpulkan bahwa pembelajaran daring berbasis MOOCs yang dikembangkan termasuk kedalam kriteria sangat layak dengan persentase 83,07 % serta memiliki karakteristik dari pembelajaran daring berbasis MOOCs dan motivasi belajar sehingga layak diujicobakan serta mendapatkan persepsi siswa dengan kategori sangat baik terhadap pembelajaran daring berbasis MOOCs dengan persentase 84,03%. Kata kunci : Pengembangan,  Pembelajaran Daring, Berbasis MOOCs, Motivasi Belajar, Suhu dan Kalor ABSTRACT This study aims to describe the location and bold learning based on MOOCs to increase students' learning motivation on temperature and heat material and get good perceptions from students. This research is a research and development (R&D) with a 4D model with the steps of define, design, development, and dissemination. Data collection techniques are non-test techniques that use observational data and questionnaires. The data analysis technique used descriptive, qualitative, and qualitative methods. The subjects used in this study were physics teachers and class XI students at SMA Negeri 1 Bengkulu City, SMA Negeri 6 Bengkulu City and SMA Negeri 9 Bengkulu City. The results of this study can be said that the developed MOOC-based bold learning includes very feasible criteria with a percentage of 83.07% and has the characteristics of MOOC-based learning and learning motivation so that it is worthy to be tested and get student perceptions in a very good category towards MOOCs-based bold learning. with a proportion of 84.03%. Keywords: RnD, e-learning, MOOCs, increase learning motivation, temperature, and heat
RESPON PESERTA DIDIK TERHADAP KETERBACAAN E-MODUL BERBASIS SSCS (SEARCH, SOLVE, CREATE, SHARE) UNTUK MELATIHKAN KEMAMPUAN BERPIKIR KREATIF PESERTA DIDIK PADA MATERI GELOMBANG DI SMA
Authors: Putra Bily Pratama , Purwanto Andik , Risdianto Eko
Published: July 2024

ABSTRAK
 
Penelitian ini bertujuan untuk melakukan uji keterbacaan guna mendeskripsikan respon peserta didik terhadap e-modul berbasis SSCS. Jenis penelitian ini merupakan penelitian pengembangan. Instrumen penelitian yang digunakan berupa angket  respon peserta didik dengan 22 butir pertanyaan yang diberikan kepada 45 responden yang merupakan peserta didik di 3 sekolah yaitu SMA Negeri 4, 7, dan 9 Kota Bengkulu. Dalam penelitian ini analisis data menggunakan deskripsi kuantitatif. Berdasarkan hasil data yang diperoleh dapat disimpulkan bahwa e-modul berbasis SSCS sangat baik berdasarkan respon peserta didik. Hal ini didasarkan pada data yang diperoleh bahwa dari seluruh pernyataan mengenai keterbacaan tehadap e-modul berbasis SSCS, hampir semuanya dijawab dengan persentase terbesar berada pada pilihan jawaban sangat setuju dan setuju. Ini berarti bahwa peserta didik setuju dengan poin-poin yang ditawarkan pada setiap pernyataan yang mereka isi pada lembar respon peserta didik. Dari data yang diperoleh juga didapatkan nilai Va sebesar 3.31 yang masuk ke kategori valid. Sedangkan nilai reliabilitas diperoleh sebesar 1.04, dan nilai tersebut lebih besar dari r tabel untuk df = 43 yaitu sebesar 0.2940, karena rhitung>rtabel maka masuk ke kategori reliabel.
 
Kata kunci :Respon Peserta Didik, Keterbacaan, E-Modul, SSCS, Berpikir Kreatif, Gelombang
 
ABSTRACT
 
This study aims to conduct a readability test to describe students' responses to SSCS-based e-modules. This type of research is development research. The research instrument used was a student response questionnaire with 22 questions given to 45 respondents who were students in 3 schools, namely SMA Negeri 4, 7, and 9 in Bengkulu City. In this study, data analysis used quantitative descriptions. Based on the results of the data obtained, it can be concluded that the SSCS-based e-module is very good based on student responses. This is based on the data obtained that of all statements regarding the readability of SSCS-based e-modules, almost all of them were answered with the largest percentage being in the answer choices strongly agree and agree. This means that students agree with the points offered in each statement that they fill out on the student response sheet. From the data obtained, the Va value of 3.31 was also obtained which entered the valid category. While the reliability value obtained is 1.04, and the value is greater than the r table for df = 43, which is 0.2940, because rcount> rtable, it is included in the reliable category.
 
Keywords: Student Response, Readability, E-Module, SSCS, Creative Thinking, Waves
RANCANG BANGUN SMART GREENHOUSE BERBASIS ARDUINO UNO
Authors: Rasyid Abdurrahman Nashih , Hamdani Dedy , Setiawan Iwan
Published: July 2024

ABSTRAK
 
Penelitian ini bertujuan untuk merancang dan membangun smart greenhouse berbasis arduino uno. Jenis penelitian ini merupakan penelitian pengembangan. Smart greenhouse yang dibangun dirancang unuk mengontrol dan memantau kondisi suhu, kelembapan tanah dan intensitas cahaya didalam smart greenhouse. Alat yang dikembangakan menggunakan Arduino uno sebagai mikrokontroler, tiga sensor, tiga aktuator serta satu modul GSM untuk memantau  kondisi didalam smart greenhouse. Sensor yang digunakan adalah YL-69 untuk mengukur kelembapan tanah, sensor DHT22 untuk mengukur suhu udara dan Sensor TEMT6000 untuk mengukur intensitas cahaya. Instrumen penelitian yang digunakan berupa lembar validasi dengan 10 butir pertanyaan yang diisi oleh 3 orang validator. Dalam penelitian ini analisis data menggunakan deskripsi kuantitatif. Berdasarkan hasil data yang diperoleh, disimpulkan bahwa rancang bangun smart greenhouse berada pada kategori sangat baik. Hal ini didasarkan pada hasil uji kelayakan alat yang divalidasi oleh 3 orang dosen ahli. Penilaian berdasarkan aspek komponen teknis adalah 100%, lalu penilaian berdasarkan aspek efisiensi adalah 95%, dari aspek ketahanan 91,66% dan aspek estetika adalah 83,33%. Sehingga dapat diambil kesimpulan dari keempat aspek tersebut bahwa media yang dikembangkan berada pada kategori baik dengan persentase rata rata hasil uji kelayakan sebesar 92,5%.
 
Kata kunci : Smart greenhouse, Arduino Uno, Sensor DHT22, Sensor YL-69, Sensor TEMT600, modul GSM900.
 
ABSTRACT
 
This study aims to design and build a smart greenhouse based on Arduino Uno. This type of research is development research. The smart greenhouse that was built was designed to control and monitor the conditions of temperature, soil moisture and light intensity inside the smart greenhouse. The tool developed uses Arduino uno as a microcontroller, three sensors, three actuators and one GSM module to monitor conditions inside the smart greenhouse. The sensors used are YL-69 to measure soil moisture, DHT22 sensor to measure air temperature and TEMT6000 sensor to measure light intensity. The research instrument used was a validation sheet with 10 questions filled in by 3 validators. In this study, data analysis used quantitative descriptions. Based on the data obtained, it is concluded that the smart greenhouse design is in the very good category. This is based on the results of the tool's feasibility test which was validated by 3 expert lecturers. The assessment based on the technical component aspect is 100%, then the evaluation based on the efficiency aspect is 95%, from the durability aspect it is 91.66% and the aesthetic aspect is 83.33%. So it can be concluded from these four aspects that the media developed is in a good category with an average percentage of 92.5% of the feasibility test results.
 
Keywords : Smart greenhouse, Arduino Uno, DHT22 sensor, YL-69, TEMT600, GSM900 module
PENGEMBANGAN LKPD BERORIENTASI PENDEKATAN SAINTIFIK PADA MATERI SUHU DAN KALOR UNTUK MELATIHKAN KETERAMPILAN BERPIKIR KRITIS SISWA SMA
Authors: Oktarina Helda , Setiawan Iwan , Medriati Rosane
Published: July 2024

ABSTRAK
 
Penelitian ini bertujuan untuk menghasilkan LKPD Berorientasi Pendekatan Saintifik pada materi suhu dan kalor untuk melatihkan keterampilan berpikir kritis siswa SMA. Metode yang digunakan dalam penelitian ini adalah metode R&D (Research and Development) dengan model pengembangan 4-D, namun pada penelitian ini dilakukan sampai tahp 3-D yang terdiri dari define, design, dan develop. Berdasarkan hasil validasi ahli pada aspek media diperoleh persentase sebesar 85% yang dikategorikan sangat layak, pada aspek materi diperoleh persentase sebesar 81,9% yang dikategorikan sangat layak, pada aspek bahasa diperoleh persentase sebesar 91,7% yang dikategorikan sangat layak. Sehingga, dapat disimpulkan bahwa LKPD Berorientasi Pendekatan Saintifik pada materi suhu dan kalor untuk melatihkan keterampilan berrpikir kritis siswa SMA berada pada kategori sangat layak dengan persentase rata-rata 86,2% dan hasil persepsi peserta didik dengan persentase rata-rata sebesar 86,06%.
 
Kata Kunci: LKPD, Pendekatan Saintifik, Keterampilan Berpikir Kritis.
 
ABSTRACT
 
This study aims to produce LKPD Oriented Scientific Approach on the material of temperature and heat to practice critical thinking skills of high school students. The method used in this study is the R&D (Research and Development) method with a 4-D development model, but in this study it was carried out to the 3-D stage consisting of define, design, and develop. Based on the results of expert validation on the media aspect, it was obtained a percentage of 85% which was categorized as very feasible, in the material aspect a percentage of 81.9% was obtained which was categorized as very feasible, in the language aspect a percentage of 91.7% was obtained which was categorized as very feasible. So, it can be concluded that the Scientific Approach Oriented LKPD on temperature and heat materials to train high school students' critical thinking skills is in the very feasible category with an average percentage of 86.2% and the students' perception results with an average percentage of 86.06%.
 
Keywords: LKPD, Scientific Approach, Critical Thinking Skills.
ANALISIS PELAKSANAAN PEMBELAJARAN IPA FISIKA SECARA DARING/ONLINE DI SMAN 3 SELUMA
Authors: Ananda Futri Dwi , Medriati Rosane , Purwanto Andik
Published: July 2024

ABSTRAK     
 
Penelitian ini bertujuan untuk (1) Mendeskripsikan perencanaan pembelajaran IPA fisika secara daring/online di SMAN 3 Seluma (2) Mendeskripsikan proses dan evaluasi pelaksanaan pembelajaran IPA fisika secara daring/online di SMAN 3 Seluma. Metode penelitian yang digunakan adalah metode penelitian deskriptif (descriptive research). Subjek penelitian adalah guru fisika dan IPA dan siswa kelas X serta XI IPA SMAN 3 Seluma. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah angket dan wawancara. Teknik analisis data pada penelitian ini yaitu dengan analisis data angket menggunakan rating scale dan analisis data hasil wawancara. Dari hasil pengolahan data diperoleh bahwa (1) Perencanaan pembelajaran IPA fisika secara daring/online di SMAN 3 Seluma berada pada kategori baik (2) Proses dan evaluasi pelaksanaan pembelajaran IPA fisika secara daring/online di SMAN 3 Seluma berada pada tingkat baik.
 
Kata Kunci : Pembelajaran daring, Pembelajaran IPA, Pembelajaran Fisika
 
ABSTRACT
 
The objective of this research was to (1) describe the online science learning plan at SMAN 3 Seluma (2) to describe the process and evaluation of the implementation of online science learning at SMAN 3 Seluma. The research method used is descriptive research method (descriptive research). The research subjects were physics and science teachers and students of class X and XI science at SMAN 3 Seluma. Data collection techniques used in this study were questionnaires and interviews. The data analysis technique in this study is by analyzing questionnaire data using a rating scale and analyzing data from interviews. From the results of data processing, it was obtained that (1) the online/online planning of physics science learning at SMAN 3 Seluma was in the good category (2) The process and evaluation of the implementation of online/online physics science learning at SMAN 3 Seluma was at a good level.
 
Keywords:  online learning, science learning, physics learning
PENGEMBANGAN E-LKPD FISIKA BERBASIS PREDICT OBSERVE EXPLAIN (POE) PADA MATERI FLUIDA STATIS UNTUK MELATIH KEMAMPUAN BERPIKIR KRITIS SISWA SMA DI KOTA BENGKULU
Authors: Oktarina Amirah Sari , Hamdani Dedy , Purwanto Andik
Published: July 2024

ABSTRAK
 
Penelitian ini bertujuan untuk mendeskripsikan kelayakan dan persepsi peserta didik terhadap Lembar Kerja Peserta Didik Elektronik (e-LKPD) berbasis Predict Observe Explain (POE) untuk melatihkan kemampuan berpikir kritis. Penelitian ini merupakan penelitian dan pengembangan (R&D) dengan model 3D dengan langkah-langkah define, design, dan develop. Teknik pengumpulan data yaitu teknik non tes yang menggunakan data observasi, review document, dan angket. Teknik analisis data yaitu dengan metode deskriptif, kualitatif, dan kuantitatif. Subjek yang digunakan pada penelitian ini adalah guru fisika dan peserta didik kelas XI di SMA Negeri 5, 7, dan 9 Kota Bengkulu. Hasil dari penelitian ini dapat disimpulkan bahwa e-LKPD berbasis POE untuk melatihkan kemampuan berpikir kritis yang dikembangkan termasuk dalam kriteria sangat layak dengan persentase rata-rata 95,06% sehingga layak diujicobakan serta mendapatkan persepsi sangat baik dari peserta didik dengan persentase rata-rata sebesar 85,69%.
 
Kata kunci: e-LKPD, POE, Kemampuan Berpikir Kritis.
 
ABSTRACT
 
This study aims to describe the feasibility and students' perceptions of the Predict Observe Explain (POE) based Electronic Student Worksheet (e-LKPD) to practice critical thinking skills. This research is a research and development (R&D) with a 3D model with the steps of define, design, and develop. Data collection techniques are non-test techniques that use observation data, document reviews, and questionnaires. Data analysis techniques are descriptive, qualitative, and quantitative methods. The subjects used in this study were physics teachers and class XI students at SMA Negeri 5, 7, and 9 Bengkulu City. The results of this study can be concluded that the POE-based e-LKPD to train critical thinking skills developed is included in the very feasible criteria with an average percentage of 95,06% so that it is worth trying out and getting very good perceptions from students with an average percentage of 85,69%.
 
Keywords: e-LKPD, POE, Critical Thinking Ability.
STUDI PENGELOLAAN EKOWISATA BERBASIS MASYARAKAT ADAT DI DESA SENARU KECAMATAN BAYAN KABUPATEN LOMBOK UTARA
Authors: Rachmansyah Deny , Nizar Wahyu Yuniati
Published: July 2024

Ekowisata berbasis masyarakat merupakan usaha ekowisata yang menitik beratkan peran aktif komunikasi. Partisipasi masyarakat dalam pembangunan adalah keikutsertaan masyarakat baik dalam bentuk peryataan maupun kegiatan. keikutsertaan tersebut terbentuk sebagai akibat terjadinya interaksi sosial antara individu atau kelompok masyarakat di dalam pembangunan. Partisispasi masyarakat dalam berbagai bentuk seperti partisipasi dalam pembuatan keputusan, perencanaan, pelaksanaan, pemantauan dan evaluasi kegiatan serta pemanfaatan hasil pembangunan.Hasil penelitian menunjukan bahwa peran serta masyarakat dalam pengelolaan objek wisata Air Terjun  Sendang Gila sangat tinggi, dikarenakan tingkat peran serta masyarakat baik pada saat rapat perencanaan, operasionalisasi serta pengawasan objek wisata Air Terjun  Sendang Gila dinilai sangat aktif, disebabkan karena objek wisata Air Terjun  Sendang Gila dimanafaatkan masyarakat selain untuk menambah pendapatan desa juga untuk menambah penghasilan masyarakat. Hal ini yang menyebabkan masyarakat berperan aktif dalam pengelolaan objek wisata Air Terjun  Sendang Gila baik dalam rapat perencanaan, menata atau mendisain kawasan objek wisata, pembangunan Infrastruktur serta pengawasan - pengawasan yang menyangkut objek wisata.
RESPONSE OF TWO VARIETIES OF RED RICE INTERCROPPED WITH SOYBEAN IN AEROBIC IRRIGATION SYSTEM TO ORGANIC FERTILIZATION USING BOKASHI OF CATTLE MANURE
Authors: Simarmata Jekson , Wangiyana Wayan
Published: July 2024

Penelitian ini bertujuan untuk mengetahui pengaruh pemupukan organik menggunakan bokashi pupuk kandang sapi terhadap pertumbuhan dan hasil dua genotip padi beras merah yang ditumpangsari dengan kedelai pada sistem irigasi aerobik pada bedeng di lahan sawah entisol. Percobaan ditata menurut Rancangan Acak Kelompok dengan 3 ulangan (blok) dan 2 faktor perlakuan yang ditata secara faktorial, yaitu varietas padi beras merah (V1= varietas Inpago Unram 1 dan V2= galur Amp-G9), dan pemupukan organik dengan bokashi pupuk kandang sapi (B1= tanpa bokashi hanya NPK dosis anjuran, B2= bokashi 20 ton/ha + NPK dosis anjuran, dan B3= bokashi 20 ton/ha + NPK 50% dosis anjuran). Penanaman padi beras merah dilakukan dengan tugal benih langsung pada bedeng dengan jarak tanam 25 x 25 cm. Hasil penelitian menunjukkan bahwa tidak terdapat pengaruh interaksi maupun varietas, namun pemupukan bokashi berpengaruh terhadap laju pertumbuhan dan beberapa komponen hasil padi beras merah termasuk hasil gabah per rumpun. Pemupukan organik dengan bokashi pupuk kandang sapi 20 ton/ha disertai pupuk NPK dosis anjuran memberikan hasil gabah tertinggi (41,6 g/rumpun), tetapi jika dosis NPK diturunkan menjadi 50% dosis anjuran terjadi penurunan hasil gabah yang signifikan (27 g/rumpun) dibandingkan dengan hanya menggunakan pupuk NPK dosis anjuran (35,1 g/rumpun), yang mengindikasikan ketergantungan produksi padi di lahan sawah irigasi yang masih tinggi terhadap pupuk NPK.
MEDICINAL USAGE OF AGARWOOD RESIN IN FORM OF ESSENTIAL OIL: A REVIEW
Authors: Wangiyana I Gde Adi Suryawan
Published: July 2024

Agarwood is a high value of non-timber commodities from Indonesia. Agarwood trade on Indonesia mostly being sold in form of raw material. This raw material is agarwood resin or also well known as ”gubal’. Processing gubal into essential oil will improve the quality and price of this commodity. Furthermore, agarwood essential oil has been reported being used as traditional medication in some countries. This medicinal activity of agarwood essential oil has been confirmed by clinical research and resulted that this material has antioxidant, antibacterial, antifungal and anticancer activity. This material also has neural activity on the nervous system and becomes a potential antidepressant, relaxative, sedative and analgesic agent. The promising of the medicinal use of agarwood essential oil suggested that processing agarwood resin into essential oil should be the number one priority on agarwood trade.
POTENSI TUMBUHAN BERGUNA DI AREAL NILAI KONSERVASI TINGGI PERKEBUNAN KELAPA SAWIT
Authors: Nahlunnisa Hafizah
Published: July 2024

Salah satu yang menjadi perhatian dalam areal nilai konservasi tinggi adalah potensi tumbuhan berguna yang terdapat di dalamnya. Tujuan dari penelitian ini adalah untuk mengidentifikasi tumbuhan berguna yang terdapat di dalam areal nilai konservasi tinggi pekebunan kelapa sawit. Lokasi penelitian di lakukan di areal NKT tiga perusahaan perkebunan kelapa sawit di Provinsi Riau. Metode pengambilan data dilakukan dengan analisis vegetasi dan studi literatur. Hasil penelitian menunjukkan bahwa spesies tumbuhan yang paling banyak ditemukan adalah berpotensi sebagai bahan bangunan sebanyak 51.35%, tumbuhan obat 47.74%, dan tumbuhan pangan 22.52%. Klasifikasi kegunaan dikelompokkan menjadi 9 kelompok. Jumlah spesies tumbuhan yang berpotensi sebagai penghasil papan/bangunan sebanyak 57 spesies, tanaman obat sebanyak 53 spesies, tanaman pangan sebanyak 25 spesies, penghasil kayu bakar 10 spesies, pakan ternak sebanyak 5 spesies, penghasil serat, anyaman, tali sebanyak 5 spesies, tanaman hias sebanyak 3 spesies, pestisida nabati sebanyak 3 spesies dan penghasil lainnya seperti damar, resin, pewarna, aromatik, lilin, gaharu, sebanyak 8 spesies. Data potensi tumbuhan berguna dapat menjadi dasar pertimbangan dalam kegiatan pemanfaatan tumbuhan di areal NKT perkebunan kelapa sawit secara lestari.
‘Reading Together’ for the Nuance: Transgender Themes and Politics in Two Tunisian Novels from the 1990s
Authors: Pardey Charlotte
Published: July 2024

Tunisian literature is only rarely studied and if it receives research attention the analysis has a monolingual focus. This article instead reads together French and Arabic works to contextualise them. Presented are: Hurlement (Screaming, 1992) by Alia Mabrouk and Ṭurshqāna (Ṭurshqāna, 1999) by Masʾūda Bū Bakr. According to the general narrative, the Arab world gave up on politics in the 1990s due to a sense of defeat and the lack of alternatives to the ruling parties’ authoritarianism. Contrary to such narratives, however, a close ‘reading together’ of the two works will bring forth political nuances.
Homies en postdeportación: riesgos y dificultades entre deportados para integrarse a la vida en Guadalajara
Authors: Jiménez Arturo Fabián , Ángel Lara Hiram Abel , Valdez Neri Eduardo
Published: July 2024

Tras los atentados terroristas del 9/11, se han implementado reformas a las leyes migratorias de Estados Unidos, lo que ha provocado deportaciones masivas de millones de mexicanos. En este artículo se busca identificar los riesgos y dificultades que particularmente enfrentan los expandilleros que han sido deportados a México tras llevar una conducta delictiva y vivir en las prisiones de Estados Unidos, y que actualmente buscan rehacer su vida en Guadalajara. Para ello, se llevó a cabo una serie de 35 encuestas, de las que se derivaron 31 casos que fueron objeto de estudio de este proyecto. El análisis de los resultados de las encuestas permitió comprender las principales dificultades que enfrentan los homies deportados para encontrar trabajo, reintegrarse a su familia y mantenerse alejados de las drogas y el alcohol.
La migración y sus efectos multidimensionales en la familia transnacional
Authors: Valencia Correa Erika , Moreno Carmona Norman Darío
Published: July 2024

En este artículo se aborda el tema de la familia transnacional de manera holística. Se analizan no solo las remesas, sino también las dinámicas y los cambios que afrontan sus integrantes como consecuencia del fenómeno migratorio. Para ello, se realizó una revisión documental en diversas bases de datos de investigaciones empíricas realizadas con familias de migrantes pertenecientes a países de Iberoamérica, principalmente de la última década. Los hallazgos sugieren que las nuevas tecnologías de la información y la comunicación han propiciado el surgimiento de nuevas dinámicas familiares y el fortalecimiento de los vínculos filiales. Además, en los contextos migratorios se evidencian las desigualdades laborales y culturales entre hombres y mujeres. Este estudio aporta al reconocimiento de que la voz de los niños es necesaria para comprender los procesos migratorios, a partir de sus vivencias y significados construidos dentro del contexto transnacional, para lo cual el escenario escolar es trascendental.
Majocchi Granuloma in the Face of an Immunocompetent Child: A Case Report
Authors: Pereira Maria Beatriz Tavares Camacho , Campos Gabriela Albernaz , Kanaan Izabel Cristina Soligo
Published: July 2024

Introduction: Majocchi granuloma (MG) is a rare infection, generally caused by the dermatophyte Trichophyton rubrum. This disease results from the proliferation of the fungus along the hair follicle into the dermal or subcutaneous tissue, causing suppurative folliculitis. Most affected patients are immunocompromised, but it is not restricted to them. Its evolution is due to prolonged use of topical steroids.

Case: We would like to introduce an interesting case of an 8-year-old female with MG in face who was treated incorrectly for several months with steroid and antibiotic that worsened the condition. After the disease was suspected, it was possible to provide adequate treatment with Terbinafine and thus, its complete regression.

Discussion: This is a presentation of MG that was treated successfully after months using incorrect drugs. We want to highlight the frequent and indiscriminate use of corticosteroids and what their abuse can lead to. The patient was treated with Terbinafina which led to resolution of the case.
A STUDY ON THE SMUGGLING OF MIGRANTS AS TRANSNATIONAL ORGANIZED CRIME IN NEPAL
Authors: Pokharel Grishma
Published: July 2024

Migrant smuggling in Nepal is a complex issue influenced by socio-economic disparities, porous borders, and transnational networks. Situated between major South Asian migration corridors, Nepal serves as both a source and transit country for migrants seeking better opportunities. Many Nepalese migrants, despite regulatory efforts, opt for irregular pathways facilitated by smugglers, exposing themselves to exploitation, abuse, and dangerous conditions. The legal and institutional frameworks in Nepal struggle to address this issue effectively. Existing laws, such as the Human Trafficking and Transportation (Control) Act and the Foreign Employment Act, offer some recourse but lack specific provisions targeting migrant smuggling, creating loopholes that smugglers exploit. The intricate networks of smugglers, recruiters, brokers, and facilitators operate across national and international borders, leveraging deception and coercion to lure vulnerable individuals. This study aims to deepen the understanding of migrant smuggling in Nepal by examining its drivers, dynamics, and impacts. Through comprehensive research and analysis, it seeks to inform evidence-based interventions and policy reforms, contributing to the broader discourse on migration governance and transnational crime in Nepal.
Revisión narrativa de la literatura: rehabilitación olfatoria en pacientes sometidos a laringectomía total
Authors: Espitia Rojas Gleidy Vannesa , Gonzalez Galvis Natalia
Published: July 2024

La laringectomía total es un procedimiento quirúrgico que implica la extracción de la laringe, ocasionando la separación de las vías aéreas superiores e inferiores, identificándose disminución en la percepción del olfato y gusto en pacientes laringectomizados totales. Sin embargo, las investigaciones actuales acerca de la rehabilitación del olfato son escasas, especialmente en América Latina. La presente revisión narrativa de la literatura tiene como objetivo presentar los métodos actuales utilizados para la rehabilitación y recuperación de la percepción el olfato en pacientes laringectomizados totales, mediante la búsqueda de literatura en la base de datos: PubMed, así como, literatura gris. Esta revisión se consolidó con base en el análisis de 35 artículos. Los resultados permitieron identificar diferentes protocolos para la evaluación del olfato, así mismo, la rehabilitación olfatoria, siendo identificados diferentes métodos como; el bypass laríngeo, enjuague sinusal, la maniobra de flujo de aire nasal espiratorio (ENAMM) y la maniobra de inducción del flujo de aire nasal (NAIM), la cual presenta mayor evidencia científica. Por lo anterior, se resalta la necesidad de analizar el impacto de los tratamientos oncológicos en la percepción del olfato y la necesidad de crear programas por parte de fonoaudiología para la rehabilitación olfatoria, generando efectos positivos en la calidad de vida de los pacientes.
Comparison of biomechanical effects of polyetheretherketone (PEEK) rods and titanium rods in lumbar long-segment instrumentation: a finite element study
Authors: Li Chao , Zhao Yao , Qi Longtao , Xu Beiyu , Yue Lei , Zhu Ranlyu , Li Chunde
Published: July 2024

Introduction

Polyetheretherketone (PEEK) lumbar fusion rods have been successfully used in short-segment posterior instrumentation to prevent adjacent segment degeneration. However, limited studies have reported their application in lumbar long-segment instrumentation. This study aimed to compare the biomechanical performances of PEEK rods and titanium rods in lumbar long-segment instrumentation using finite element (FE) models, with the expectation of providing clinical guidance.

Methods

A lumbar FE model (A) and four lumbar fixation FE models (BI, CI, BII, CII) of the L1–S1 vertebral body were developed using CT image segmentation (A: intact model; BI: intact model with L2–S1 PEEK rod internal fixation; CI: intact model with L2–S1 titanium rod internal fixation; BII: intact model with L3–S1 PEEK rod internal fixation; CII: intact model with L3–S1 titanium rod internal fixation). A 150-N preload was applied to the top surface of L1, similar to the intact model. The stresses on the lumbar intervertebral disc, facet joint, pedicle screws, and rods were calculated to evaluate the biomechanical effect of the different fixation procedures in lumbar long-segment instrumented surgery.

Results

Under the four physiological motion states, the average stresses on the adjacent segment intervertebral disc and facet joint in all fixation models were greater than those in the intact model. Furthermore, the average stresses on the adjacent segment intervertebral disc and facet joint were greater in models CI and CII than in models BI and BII, respectively. The average stresses on the pedicle screws and rods were decreased in models BI and BII compared with models CI and CII under the four physiological motion states, respectively.

Discussion

The PEEK rod internal fixation system may have better biomechanical properties than the titanium rod internal fixation system in delaying adjacent segment degeneration, improving the lumbar function of postoperative patients, and reducing the risk of screw loosening and breakage in lumbar long-segment instrumentation.
Role of actin-binding proteins in prostate cancer
Authors: Fu Fangzhi , Yu Yunfeng , Zou Bo , Long Yan , Wu Litong , Yin Jubo , Zhou Qing
Published: July 2024

The molecular mechanisms driving the onset and metastasis of prostate cancer remain poorly understood. Actin, under the control of actin-binding proteins (ABPs), plays a crucial role in shaping the cellular cytoskeleton, which in turn supports the morphological alterations in normal cells, as well as the invasive spread of tumor cells. Previous research indicates that ABPs of various types serve distinct functions, and any disruptions in their activities could predispose individuals to prostate cancer. These ABPs are intricately implicated in the initiation and advancement of prostate cancer through a complex array of intracellular processes, such as severing, linking, nucleating, inducing branching, assembling, facilitating actin filament elongation, terminating elongation, and promoting actin molecule aggregation. As such, this review synthesizes existing literature on several ABPs linked to prostate cancer, including cofilin, filamin A, and fascin, with the aim of shedding light on the molecular mechanisms through which ABPs influence prostate cancer development and identifying potential therapeutic targets. Ultimately, this comprehensive examination seeks to contribute to the understanding and management of prostate diseases.
Chia seed-mediated fabrication of ZnO/Ag/Ag2O nanocomposites: structural, antioxidant, anticancer, and wound healing studies
Authors: Rafique Aisha , Amjad Fatima , Janjua Muhammad Ramzan Saeed Ashraf , Naqvi Syed Ali Raza , Hassan Sadaf Ul , Abdullah Hanzla , Nazir Muhammad Shahid , Ali Zulfiqar , Alshihri Abdulaziz A. , Momenah Maha Abdullah , Mansour Adel Abo , Bajaber Majed A. , Alalwiat Ahlam A.
Published: July 2024

Plant extract-mediated fabrication of metal nanocomposites is used in cell proliferation inhibition and topical wound treatment, demonstrating significant effectiveness. Salvia hispanica L. (chia) seed extract (CE) is used as the reaction medium for the green fabrication of ecofriendly ZnO(CE) nanoparticles (NPs) and Ag/Ag2O(CE) and ZnO/Ag/Ag2O(CE) nanocomposites. The resultant nanoparticles and nanocomposite materials were characterized using UV–visible, Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), and energy-dispersive X-ray (EDX) techniques. In the context of antioxidant studies, ZnO/Ag/Ag2O(CE) exhibited 57% reducing power and 86% 2,2, diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging. All three materials showed strong antibacterial activity against Staphylococcus aureus (S. aureus), Escherichia coli (E.coli), and Bacillus subtilis (B. subtilis) bacterial strains. Additionally, ZnO(CE), Ag/Ag2O(CE), and ZnO/Ag/Ag2O(CE) also revealed 64.47%, 42.56%, and 75.27% in vitro Michigan Cancer Foundation-7 (MCF7) cancer cell line inhibition, respectively, at a concentration of 100 μg/mL. Selectively, the most effective composite material, ZnO/Ag/Ag2O(CE), was used to evaluate in vivo wound healing potential in rat models. The study revealed 96% wound closure in 10 days, which was quite rapid healing compared to wound healing using clinically available ointment. Therefore, in conclusion, the ZnO/Ag/Ag2O(CE) nanocomposite material could be considered for further testing and formulation as a good anticancer and wound healing agent.
Prognostic significance of soluble PD-L1 in prostate cancer
Authors: Zvirble Margarita , Survila Zilvinas , Bosas Paulius , Dobrovolskiene Neringa , Mlynska Agata , Zaleskis Gintaras , Jursenaite Jurgita , Characiejus Dainius , Pasukoniene Vita
Published: July 2024

Purpose

The aim of this study was to assess the role of sPD-L1 and sPD-1 as potential biomarkers in prostate cancer (PCa). The association of the values of these soluble proteins were correlated to the clinical data: stage of disease, Gleason score, biochemical recurrence etc. For a comprehensive study, the relationship between sPD-L1 and sPD-1 and circulating immune cells was further investigated.

Methods

A total of 88 patients with pT2 and pT3 PCa diagnosis and 41 heathy men were enrolled. Soluble sPD-L1 and sPD-1 levels were measured in plasma by ELISA method. Immunophenotyping was performed by flow cytometry analysis.

Results

Our study’s findings demonstrate that PCa patients had higher levels of circulating sPD-L1 and sPD-1 comparing to healthy controls (p < 0.001). We found a statistically significant (p < 0.05) relationship between improved progression free survival and lower initial sPD-L1 values. Furthermore, patients with a lower sPD-1/sPD-L1 ratio were associated with a higher probability of disease progression (p < 0.05). Additionally, a significant (p < 0.05) association was discovered between higher Gleason scores and elevated preoperative sPD-L1 levels and between sPD-1 and advanced stage of disease (p < 0.05). A strong correlation (p < 0.05), between immunosuppressive CD4+CD25+FoxP3+ regulatory T cells and baseline sPD-L1 was observed in patients with unfavorable postoperative course of the disease, supporting the idea that these elements influence each other in cancer progression. In addition to the postoperative drop in circulating PD-L1, the inverse relationship (p < 0.05), between the percentage of M-MDSC and sPD-L1 in patients with BCR suggests that M-MDSC is not a source of sPD-L1 in PCa patients.

Conclusion

Our findings suggest the potential of sPD-L1 as a promising prognostic marker in prostate cancer.
Integrative GWAS and eQTL analysis identifies genes associated with resistance to Vibrio harveyi infection in yellow drum (Nibea albiflora)
Authors: Huang Ying , Li Jiacheng , Li Wanbo , Han Fang
Published: July 2024

Vibrio harveyi is a major pathogen in yellow drum (Nibea albiflora) aquaculture, causing significant mortality and economic losses. In this study, using the latest assembled reference genome of yellow drum by our laboratory, we conducted genome-wide association study (GWAS) analysis on 345 individuals (197 susceptible and 148 resistant). The analysis revealed 24 significant single nucleotide polymorphisms (SNPs) on chromosome 24 within a 217 Kb region. The estimated heritability for all genome-wide SNPs was 0.3578, while the heritability for the 24 significant SNPs was 0.0710. Four candidate genes were identified within this region: Suppressor of Cytokine Signaling 1 (SOCS1), C-type Lectin Domain Family 16A (CLEC16A), Major Histocompatibility Complex Class II Transactivator (CIITA), and Protein Kinase Cβ (PRKCB). Subsequently, expression quantitative trait loci (eQTL) analysis was performed on transcriptome sequencing data from spleen tissues of 78 individuals from the resistant group. On average, each chromosome harbored 49,396 eQTL loci, with an average of one SNP regulate 1.3 genes. Notably, 22.79% of SNPs showed significant associations with the expression of one or more genes. By integrating GWAS and eQTL data, seven SNPs were identified to have significant associations with regulated genes in the eQTL results. All seven SNPs were found to target the same gene, namely Zinc Finger Protein yd23210 in yellow drum. This study provides genetic markers and candidate genes for molecular breeding of yellow drum against V. harveyi infection, offering insights into the molecular immune mechanisms and potential pathways for genetic improvement of disease resistance traits in this species.
Determinants of anemia among patients receiving cancer chemotherapy in Northwest Ethiopia
Authors: Wondm Samuel Agegnew , Dagnew Samuel Berihun , Gubae Kale , Tesfaye Tegenu Chanie , Tamene Fasil Bayafers
Published: July 2024

Background

Chemotherapy-induced anemia (CIA) is a hematologic complication that frequently affects patients with cancer undergoing chemotherapy. It is associated with worse treatment outcomes, higher rates of morbidity and mortality, worse quality of life, and higher healthcare costs. The incidence and predictors of CIA in Ethiopia, particularly in Northwest Ethiopian oncology centers, are poorly understood. This study was conducted at Northwest Ethiopian oncology centers to evaluate the incidence and determinants of chemotherapy-induced anemia in adult patients with cancer undergoing chemotherapy.

Methods

This 3-year hospital-based retrospective follow-up study included adult patients with cancer receiving chemotherapy between 2019 and 2021 at two oncology centers in Northwest Ethiopia. Data were collected from October to December 2021. A binary logistic regression model was used to select variables and determine the Crude Odds Ratio (COR). Variables with P-value < 0.2 were entered into the multivariable logistic regression and Adjusted odds ratio (AOR) with 95% Confidence intervals (CI) for variables with P-value < 0.05 were estimated to show determinants of chemotherapy-induced anemia among cancer patients who received chemotherapy.

Results

A total of 402 patients were included in the final analysis. The overall incidence of CIA was 75.4% (95% CI 70.7, 79.8). Older age [AOR = 1.8, 95% CI (1.4–3.5); P = 0.043], hematologic cancer [AOR = 3.7, 95% CI (3.2–5.7), P = 0.021], obesity [AOR = 3.4, 95% CI (2.3–6.9); P = 0.028], ≥6 chemotherapy cycles [AOR = 3.8, 95% CI (3.2–5.1), P = 0.019], cancer metastasis to bone [AOR = 2.9, 95% CI (1.2–4.7), P = 0.025] were statistically significant predictors of chemotherapy-induced anemia.

Conclusion

Chemotherapy-induced anemia persisted in a significant percentage of cancer patients. Chemotherapy-induced anemia developed in three-quarters of patients undergoing chemotherapy. Chemotherapy-induced anemia was significantly associated with older age, hematologic malignancy, obesity, a greater number of chemotherapy cycles, and cancer metastasis to bone. To lower the risk of morbidity related to anemia, patients with chemotherapy-induced anemia should be regularly evaluated and treated with appropriate treatment.
Mycorrhizal association and its relation with pteridophytes
Authors: Kumari Pratibha , Bhatia Meenam , Giri Priti , Uniyal Prem Lal
Published: July 2024

Mycorrhizal association is one of the earliest and diversely distributed symbiotic associations on the Earth. This association helped early terrestrial plants to colonize the land by improved supply of nutrients like phosphate, nitrogen and zinc. It also helped plants to tolerate unfavorable soil conditions with increased water retention capacity, resistance to drought and pathogens. In return, fungi benefitted with carbon as their food source from the plants. More than 80% of terrestrial plants including pteridophytes, gymnosperms and angiosperms are reported to form arbuscular mycorrhizal (AM) association. Plants with root systems appeared on land during the Devonian period and many of them like pteridophytes still exist today. Various molecular and fossil studies confirm that the plants belonging to Ordovician-Devonian are associated with fungi, which are very similar to genus Glomus. AM association is very common in pteridophytes and the growth of its sporophyte and gametophyte is directly affected in the presence of AM association. Pteridophytes as early land plants with root systems have a very significant place in the plant kingdom. They have evolved and adapted to fill various habitats and facilitated early terrestrialization of other land plants by providing suitable niche with the help of AM fungi. In spite of pteridophytes being a very important plant group in the land system, very few reports are available on fungal-pteridophyte association. The present review is an effort to gather information about AM association in pteridophytes that might help in unraveling the evolution and significance of plant and fungi association.