bluuebunny/crossref_metadata_2025 huggingface dataset:
Health Related Quality of Life in Chronic Obstructive Pulmonary Disease Patients
Authors: Sabir Aimen , Shazia Nisar  , Khalid Mahmood Raja  , Ayesha Anwer  , Marriam Hussain Awan  , Maria Tariq
Published: October 2023

Objective: To determine the health-related quality of life among patients suffering from chronic obstructive pulmonary disease.
Study Design: Cross sectional analytical study.
Place and Duration of study: Medicine/pulmonology department of Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan 2019 to Jan 2020.
Methodology: Two hundred and fifty patients of chronic obstructive pulmonary disease diagnosed for more than one year byv a consultant medical specialist or pulmonologist were included in the study. Health related quality of life was assessed by using the chronic obstructive pulmonary disease Assessment Test (CAT). Socio-demographic factors in the study were correlated independently with the decline in quality of life by using the binary logistic regression.
Results: Out of 250 patients of chronic obstructive pulmonary disease, 122(48.8%) had normal health related quality of life while 128(51.2%) had compromised quality of life. Mean age of the study participants was 50.71±2.26 years. Advancing age of the patients and long duration of chronic obstructive pulmonary disease had statistically significant association with compromised health related quality of life (p-value<0.05) when binary logistic regression was applied.
Conclusion: Health related quality of life was found compromised among more than half of the chronic obstructive pulmonary disease patients in our study. Patients who were elderly or those who were having symptoms of chronic obstructive pulmonary disease for more than five years had more chances of having compromised health related quality of life as compared to patients with lesser age and short duration of illness.
Pain Management of Patients under General Anaesthesia Nalbuphine Alone or Nalbuphine with Ketorolac
Authors: Shehzad Farrukh , Bushra Zafar  , Maqsood Ahmed  , Nadia Arif  , Qaseem Ahmed Raja  , Nabeel Ahmed Butt
Published: October 2023

Objective: To compare the efficacy of Nalbuphine alone versus Nalbuphine with Ketorolac for the management of pain in for open cholecystectomy under general anaesthesia.
Study Design: Comparative prospective study.
Place and Duration of Study: Anaesthesia department of CMH, Okara Cantt Pakistan, June 2019- March 2020.
Methodology: Patients were divided into two Groups by the lottery method, Group-A, Nalbuphine (.12milligram/kilogram) and Group-B (Nalbuphine .06millig/kilogram+ Ketorolac 15milligram).They were all given standard anesthetic drugs and analgesics in above mentioned dose at the start of surgery. Patients were assessed regarding postoperative pain intensity using the Numerical Pain Rating Scale at 5minute, 30 minutes and 1 hour after shifting to recovery. Rescue analgesia for moderate to severe pain at 30 minutes was documented. Nausea, vomiting and sedation were also noted in both groups.
Results: Sedation in Group A was 8(10.7%) as compared in Group-B 4(5.3%).The frequency of nausea and vomiting in Group A and Group-B was 6(8.0%), 4(5.3%), and 5(6.7%), 2(2.7%) respectively. Rescue analgesia being lower in Group-A compared to Group-B which was statistically significant, for moderate to severe pain at 30 minutes after shifting. Group-A 10(13.3%) of cases while Group-B 55(73.3%) of cases producing p-value 0.001.A statistically significant difference regarding pain score between both groups, p-value <0.001.
Conclusion: Intravenous Nalbuphine (0.12 mg/kg) was more effective in reducing pain intensity and postoperative analgesic requirements after surgery as compared to Nalbuphine (.6mg/kg)+ Ketorolac (15mg) in combination.
ALK Gene Rearrangemnet in Lung Adenocarcinoma
Authors: Rani Berkha , Ghulam Haider  , Sana Sehar  , Versha Rani Rai  , Fnu Raja  , Maliha Ashfaq
Published: October 2023

Objective: To assess the frequency of ALK gene rearrangement among patients presenting with lung adenocarcinoma at tertiary care hospital of Karachi, Pakistan.
Study Design: Prospective longitudinal study
Place and Duration of Study: Department of Medical Oncology, Jinnah Postgraduate Medical College Karachi, Pakistan from May 2019 Mar 2020.
Methodology: Total 185 patients with confirmed diagnosis of stage IV lung adenocarcinoma who were unresectable and metastatic of age 20-75 years of either gender were included in the study using non-probability consecutive sampling technique. Patients were subjected for ALK mutation analysis using fluorescent in situ hybridization technique.
Results: Out of 185 patients, the ALK rearrangements were found positive in 27 tumors whereas it was negative in 158 tumors. Among ALK positive cases, majority of the patients were of aged less than 50 years (n=18, 66.7%).The statistically significant difference was found between age and ALK gene rearrangement (p<0.05). Whereas no statistically significant relationship was found between ALK rearrangements and gender, ethnicity and smoking status (p>0.05).
Conclusion: The results showed positive rearrangement of ALK gene in 15% of the patients which is in contrast to 7% patients found in western studies. ALK gene testing has become standard of care in patients of adenocarcinoma who are EGFR negative so that treatment like ALK gene inhibitors such as alectinib, brigatinib, ceritinib, crizotinib, and lorlatinib can be tailored accordingly.
Functional Recovery Measurement: Comparing Early Active Mobilization Versus Immobilization after Extensor Tendon Repair in Zones IV to VIII
Authors: Zahid Zaara , Ali Hyder , Khursheed Roqayyah Munawwer , Sami Waqas , Farhina Maha
Published: October 2023

Objective: To compare the results of early active mobilization versus immobilization in term of rehabilitation after extensor tendon injury in zones IV–VIII.
Study Design: Randomized control trial (Clinical Trial no. NCT04221113).
Place and Duration of Study: Department of Plastic and Reconstructive Surgery, Dr. Ruth K.M. Pfau Civil Hospital, Karachi Pakistan, from Feb to Jul 2020.
Methodology: Patients with extensor tendon injuries of zone IV–VIII were randomly allocated to Treatment Group (early Active Mobilization) and Comparison Group (Immobilization Group) and their total active motion score was observed at fourth, sixth and eighth week.
Results: Overall mean age of study participants was 29.48±5.51 years. Half of the patients had single finger injury 25(50%). Most of the study participants presented with injury in zone V 32(64%). The two groups did not differ on basis of age (p=0.879), gender (p=1.00), zone involved (p=0.183) and finger involved (p=0.396). TAM score between the two groups was not significantly different at fourth week (p=0.384), sixth week (p=0.606) and eighth week (p=0.122). The frequency of complications between two groups was not statistically significantly different (p=0.667).Conclusion: The current study was unable to find the significant difference in patients’ outcomes when treated with early active mobilization and immobilization protocol.
Outcomes of the Use of Direct-Acting Antiviral Therapy in Patients of Chronic Hepatitis-C of Genotype 3a
Authors: Zahoor Sarmad , Sikander Abdullah  , Muhammad Ahmed Saifullah  , Saroosh Zahoor  , Khan Amer  , Ali Shoaib
Published: October 2023

Objective: To measure the outcomes of direct acting Antiviral therapy in terms of frequency of Hepatocellular carcinoma after its use of in HCV patients infected with 3a genotype and to analyze the efficacy of double and triple regimen in HCV patients of Child Pugh’s class A and B respectively.
Study Design: Quasi- experimental study.
Place and Duration of Study: Mayo Hospital, Lahore Pakistan, from May to Dec 2019.
Methodology: After applying inclusion and exclusion criteria 262 patients of 3a genotype were awarded as Child Pugh’s Class A and B and were treated with double and triple regimen for 12 and 24 weeks respectively. They were followed up with Ultrasound Abdomen every month and PCR Quantitative was done for evaluating Sustained Virological Response after 3 months of completing treatment.
Results: Out of 262 patients, 141(53.8%) were male and 121(46.2%) were female. 243(92.7%) patients achieved Sustained Virological Response. 9(3.4%) developed Hepatocellular carcinoma of which 8 were on triple regimen and 1 on double regimen.
Conclusion: direct Acting Antivirals are effective in achieving Sustained Virological Response but pose a greater risk for Hepatocellular carcinoma. So, they should be used with caution and serial monitoring.
Assessment of Endothelial Cell Count Changes Post-Yttrium Aluminium Garnet Laser for Posterior Capsular Opacification
Authors: Khan Amna , Abdul Rauf  , Muhammad Haroon Sarfraz  , Summaya Khan  , Taimoor Ashraf  , Nazia Iqbal
Published: October 2023

Objective: The study aimed to assess the effect of Neodymium : Yttrium Aluminium Garnet laser (ND:YAG laser) on endothelial cell count loss and anterior segment elements.
Study Design: Quasi-experimental.
Place and Duration Of Study: Armed Forces Institute of Ophthalmology, Rawalpindi from Jul 2021 to Feb 2022.
Methodology: A total of 60 patients with a history of posterior capsular opacities planned for Neodymium: Yttrium Aluminium Garnet laser posterior capsulotomy were included. Specular microscopy was done pre and post-laser to study and parameters such as central corneal thickness, endothelial cell count, intra-ocular pressure was noted. Data were analyzed by using the Statistical Package for the Social Sciences version 23 software
Result: After four weeks of Neodymium : Yttrium Aluminium Garnet laser, there was no significant change in the intraocular pressure (p=0.334), however, the visual acuity improved from 0.6±0.3-0.05±0.1 (p<0.001) along with a decrease in endothelial cell count 2101±485-1919±427 (p<0.001) and central corneal thickness 0.504±0.03-0.502± 0.03 (p=0.010). A similar trend of changes in the parameters was observed for lower (1.0-1.2MJ) and higher energy (2.1-2.5MJ) in the sample for posterior capsulotomy.
Conclusion: Our study concluded that the corneal structural changes occur post-Neodymium: Yttrium Aluminium Garnet posterior capsulotomy, including changes in endothelial cell count. However, there is no significant disturbance in the intraocular pressure after the procedure.
Comparison of Intraocular Pressure Measurement by Goldmann Applanation Tonometer, Air Puff Tonometer and Tonopen in Vitrectomized Eyes
Authors: Ghani Muhammad Usman , Mukhtar Muhammad Ahsan , Khan Taimoor Ashraf , Shahid Muhammad , Rauf Abdul , Taimoor Ijlal
Published: October 2023

Objective: To compare Goldmann applanation tonometer, air puff tonometer, and tonopen measured IOP Readings in vitrectomized eyes filled with temponading oils and gasses.
Study Design: Comparative cross-sectional study.
Place and Duration of Study: Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi Pakistan, from Aug 2021 to Feb2022.
Methodology: A total of 50 eyes were included in our study. Intraocular pressure was measured by an experienced ophthalmologist between 10am to 4pm on the 7th postoperative day by three devices, Goldmann applanation tonometer (GAT), air puff tonometer, and tonopen. Pearson’s correlation and paired samples t-test was applied to determine correlation and any significant difference between the mean of intraocular pressure measured by three different devices.
Results: Out of the 50 people included in study 31(62%) were males and 19(38%) were females. The mean age of study participants was 50.10±11.61 years. Mean intraocular (IOP) pressure measured by the GAT applanation tonometer was 14.59±1.13 mmHg. Mean IOP as calculated by the airpuff tonometer was 15.93±1.88 mmHg, whereas mean IOP as calculated by tonopen was 15.85±1.86 mmHg. All three instrument values showed significant difference as p-value < 0.001.
Conclusions: The air puff tonometer overestimates IOP as compared to GAT. Tonopen and air puff tonometer produce IOP measurements that are similar and consistent to each other but not to GAT
ԱՐԴԻ ՀԱՅԵՐԵՆԻ ԽՈՍՔԱՅԻՆ ԳՈՐԾՈՒՆԵՈՒԹՅԱՆ ԻՄԱՍՏԱՅԻՆ ԵՆԹԱԴԱՇՏԻ ԲԱՅԵՐԻ ՇԱՐԱԿԱՐԳԱՅԻՆ ԱՌԱՆՁՆԱՀԱՏԿՈՒԹՅՈՒՆՆԵՐԸ / SYNTAGMATIC PECULIARITIES OF VERBS OF SEMANTIC SUBFIELD OF SPEECH ACTIVITY IN MODERN ARMENIAN
Authors: DOKHOYAN RUZANNA
Published: October 2023

The syntagmatic relations of nuclear verbs "to say", "to think", "to feel", "to behave" belonging to the lexico-semantic groups of the verbs of “saying”, “thinking”, “perception” and “behavior” as a subfiled within the semantic field of “Speech activity” in modern Armenian are studied in the article from the perspective of their collocobility. The paper discusses the similarities and differences of their collocobility conditioned by the semantic and syntagmatic principles of grouping of the above-mentioned verbs. Then the valence of the mentioned verbs is examined, as well as the syntagmatic structural types of both nuclear verbs and the ones grouped around the nucleus. The common feaures disclosed by the study testify to the systemic structure of the given subfield.
The Sufficient Accuracy of Green Claims Used in Marketing
Authors: Kokkonen Katariina
Published: October 2023

The article discusses green claims used in marketing, and how such claims can be made with sufficient accuracy as required by EU law. The article is based on the author’s Bachelor’s thesis, which examines the factors that affect the assessment of the matter. The article is limited to discussing about marketing communications and other communications given to the consumer in support of the environmental claim and accompanied by space restrictions imposed by the media used. The research methods used in this article are legal dogmatics and comparative law, the former focusing on the interpretation of EU law in the Finnish legal system and the latter focusing on the Swedish Patent and Market Court. Legal dogmatics is used to assess how the question of accuracy is more specifically formed according to current law. Meanwhile, comparative law is used to find support for the legal guidelines that can be interpreted from the Finnish Consumer Ombudsman’s rulings. After the introduction, the article defines the terms green claim and average consumer as the basis for the assessment of green claims. It defines when green claims can be considered to be prohibited greenwashing. Greenwashing is not a concept defined in legislation or other sources of law, but a generic word used in research to signify possibly illegal conduct. Next, the article looks into the key marketing regulations concerning the subject. Lastly, the article concentrates on the authority guidelines and rulings by the Finnish and Swedish Consumer Ombudsman. The article concludes that if the green claim is found to be ambiguous, additional information about its veracity should be located in a “close proximity” to the claim. On the basis of the recent rulings, it is unclear what “close proximity” means. When assessing the distance, the means of communication and the nature of marketing should be considered. Therefore, it should be taken into consideration whether the marketing is about a specific consumer good, or rather about general image marketing. However, in a digital setting, it is clear that the information cannot be located several “clicks” away from the claim.
STUDY OF THE ANALGESIC ACTIVITY OF(S)-1-METHYL-3-(1-(5-PHENYL ISOXAZOLE-3-CARBONYL) PIPERIDINE-2-IL) PYRIDINE-1-IUM IODIDE
Authors:   E.A. Buketov Karagandy University N-PLC, Karaganda, Kazakhstan, Mukusheva G.K. , Zhasymbekova A.R. ,   E.A. Buketov Karagandy University N-PLC, Karaganda, Kazakhstan, Aliyeva M.R. ,   E.A. Buketov Karagandy University N-PLC, Karaganda, Kazakhstan, Kaiyrbayeva M. Zh. ,   E.A. Buketov Karagandy University N-PLC, Karaganda, Kazakhstan, Mazhitov A.S. ,   Abai Kazakh National Pedagogical University, Almaty, Kazakhstan
Published: October 2023

Recently, the attention of specialists to medicines of natural origin has been constantly growing. The interest in the use of such drugs obtained from natural raw materials is justified by high efficiency, a wide range of pharmacological activity, as well as the possibility of using them for a long time without complications and side effects. The share and volume of production of medicinal products is increasing all over the world, through synthetic transformations of substances isolated from wild and cultivated plants. Substances of plant origin are widely used as biologically active additives, agrochemical agents. Research in the field of modern chemistry of plant substances in the Republic and abroad is devoted to a comprehensive and comprehensive study of plant raw materials, including the extraction and designation of the structure and chemical properties of plant components, the study of their biological activity, the development of effective and environmentally safe methods for complex processing of plant raw materials. The attractiveness of alkaloid derivatives to compounds is due to the versatility of their reactivity, as well as the practical use of alkaloid derivatives as medicines. Modification of the molecules of natural compounds by introducing such a substituent is one of the promising directions in the search for new biologically active compounds. Analysis of the results of analgesic activity assessment experiments showed that(s)-1-methyl-3-(1-(5-phenylisoxazole-3-carbonyl) piperidine-22 Il) pyridine-2-Il) pyridine-1-IUM iodide has the ability to reduce the severity of specific nociceptive responses in rats during chemical irritation of the peritoneum. The analgesic activity of the test sample was analyzed on diclofenac sodium.
SYNTHESIS OF A DOUBLE COMPOUND BASED ON DIMETHYLOL UREA AND PHYTOCOMPOUND OF MOLYBDENUM AND THE STUDY OF ITS INFLUENCE ON THE POPULATION OF SOME SOIL MICROORGANISMS AND ACCUMULATION OF NITROGEN
Authors:   A.B. Bekturov Institute of Chemical Sciences JSC, Ramazanova E.N. , Usmanov S. ,   A.B. Bekturov Institute of Chemical Sciences JSC, Yeserkeeva N.N. ,   A.B. Bekturov Institute of Chemical Sciences JSC, Zholmaganbetova M. A. ,   Kazakh National Women's Pedagogical University, Myachina O.V. ,   Institute of General and Inorganic Chemistry, Mahmudov R.U. ,   LLP NPO Ana Zher, Usmanov H.S. ,   LLP NPO Ana Zher
Published: October 2023

Drillers used for agricultural crops, in particular cotton seeds, cannot provide additional nitrogen feeding in the required volume during a shortage of nitrogen fertilizers. This article sets the task of creating a new active substance based on the phyto compound dimethylolure and molybdenum, which allows you to reduce cotton diseases in cotton cultivation, increase the accumulation of light hydrolyzed nitrogen in the soil and obtain a high cotton yield. The purpose. Study of chemical interactions in a three-component aqueous-salt system of dimethylolure-molybdenum phyto-compound-water by isothermal method. Objects. DMM, FSMo, double compound DMM is the active reactant of FSMo. Results.The isothermal method at a temperature of 25°C found that in the concentration range of solutions of 12.2-9.8% DMM and 2.8-5.4% FSMo, DMM crystallizes in the system, at a concentration range of 5.7-2.1% DMM and 12.3-15.5% FSMo, FSMo crystallizes, and in the concentration range of 8.2 -6.4% DMM and 6.2-9.3% FSMo, the compound DMM•FSMo is separated from the solution into this phase.Conclusion. The chemical interaction in the water-salt system dimethylol urea (DMM) - molybdenum phytocompound (FSMo) - water was studied by isothermal methods of chemical analysis. The region of crystallization of a new double compound, an active substance based on DMM and FSMo, was established at a molar ratio of 4DMM•FSMo. On model soil samples, it was determined that the active substance - the double compound 4DMM•FSMo against the background of ammonium nitrate, in comparison with ammonium nitrate, increases the number of nitrogen-fixing bacteria by 3.0 and 3.2 times.
QUANTUM CHEMICAL STUDY OF HYDROGENATION OF SUNFLOWER OIL OVER NICKEL CATALYSTS
Authors:   Al-Farabi Kazakh National University, Sailau Zh.A. , Almas N.Zh. ,   International Science Complex Astana, Aimaganbetov K. P. ,   Al-Farabi Kazakh National University, Almaty, Kazakhstan, Kurbanova B. A. ,   L.N. Gumilyov Eurasian National University, Astana, Kazakhstan, Toshtay K. ,   International Science Complex Astana, Aldongarov A.A. ,   International Science Complex Astana
Published: October 2023

Vegetable oil hydrogenation is vital in edible margarine production, preventing rapid deterioration caused by double bond oxidation. Hydrogenation preserves vegetable oils by countering double bond oxidation, ensuring product quality. During this process, geometric isomers, notably trans isomers, form, driven by thermodynamic stability. Nickel catalysts are crucial in the oil and ghee industry for efficient hydrogenation. Purpose. Our study investigates the hydrogenation of sunflower oil with nickel catalysts, aiming to uncover molecular dynamics and interactions shaping this process. We reveal essential insights into linoleic acid-nickel interactions, elucidating hydrogenation mechanisms and implications for glycerol production. Methodology. Quantum chemical calculations and HyperChem software were employed to study the linoleic acid-nickel interaction during hydrogenation. This study delves into the hydrogenation of sunflower oil using nickel catalysts, employing quantum chemical calculations and HyperChem software. Results. Our research elucidates robust linoleic acid-nickel interactions through optimized structures, molecular electrostatic maps, molecular orbitals, bond lengths, and energies. These findings enhance our understanding of hydrogenation mechanisms. Additionally, we found that nickel-metal interactions primarily drive glycerol production from biofuels, promising efficiency gains. Conclusion. Our study yields insights into vegetable oil hydrogenation with nickel catalysts, optimizing processes in the oil and ghee industry. Furthermore, it has implications for glycerol production from biofuels, offering potential advancements in this area.
Modern trends in the formation of comorbid pathology of the esophagus and gastroduodenal zone in children
Authors: Pavlenko Nataliia , Solodovnichenko Irina , Shutova Olena , Babadzhanyan Olena , Voloshyna Lidiia , Hanzii Olena
Published: October 2023

The article presents modern views on trends and controversial issues in the formation of combined pathology of the gastroduodenal zone and esophagus in children. The purpose of the authors of this study: to identify the features of the formation, course and outcomes of gastroesophageal reflux disease (GERD) in children with pathology of the gastroduodenal zone (GDZ) based on endoscopic and morphological comparisons. Own long-term observations were analyzed depending on the type of pathology, the severity of motor disorders, endoscopic and morphological picture, infection Helicobacter pylori. Possible options for the formation of gastroesophageal reflux disease in children and adolescents with various diseases of the gastroduodenal zone were determined. It has been established that the combined nature of the pathology of the esophagus and gastroduodenal zone in children occurs in more than 75% of patients. The nature and severity of esophageal disorders depend on the nature of the nosology of the gastroduodenal zone and, as a rule, are secondary. The increase in the frequency of GERD in modern children, the increase in the proportion of its complicated variants (including ulcers and Barrett's esophagus), make it a priority in the study of diseases of the upper digestive tract in children at the present time. For this contingent of young patients, it is urgent and urgent to develop clear diagnostic criteria (including endoscopic and morphological criteria), therapy tactics, and a strategy for cancer prevention.
DIGITAL TRANSFORMATION IN BANKING: A REVIEW OF NIGERIA'S JOURNEY TO ECONOMIC PROSPERITY
Authors: Oluwaseun Augustine Lottu  , Adekunle Abiola Abdul  , Donald Obinna Daraojimba  , Ayoola Maxwell Alabi  , Adesola Adepeju John-Ladega  , Chibuike Daraojimba
Published: October 2023

The extensive economic ramifications of Nigeria's banking sector's multifaceted digital transformation are examined in this study. The "Giant of Africa," Nigeria, has undergone a significant transformation in its banking practices, adopting cutting-edge digital technologies to boost productivity, advance financial inclusion, and stimulate economic growth. The study identifies key elements of the banking industry's digital transformation, emphasizing the function of online platforms, digital payments, blockchain technology, and cryptocurrencies. Additionally, it explores the forces propelling this transformation, such as customer demands for seamless experiences, increased competition from fintech startups, and governmental requirements for greater transparency. The research also offers a thorough overview of Nigeria's banking industry and economic environment, highlighting its historical reliance on conventional methods and willingness to adopt digital innovations. It exemplifies how digital transformation affects economic growth, investment, entrepreneurship, and job creation outside banking institutions. The study suggests advancing digital transformation in Nigerian banking, including bolstering cybersecurity spending, updating technology infrastructure, and encouraging cooperation with fintech partners. Furthermore, it promotes customer education and ongoing innovation as crucial for long-term success. The study's findings highlight the potential for economic prosperity and the challenges that must be overcome. It also sheds light on the transformational path of Nigerian banking. Nigerian banks can navigate the digital environment and significantly enhance the nation's economy.

Keywords: Digital Transformation, Nigerian Banking Sector, Regulatory Compliance, Cybersecurity, Data Privacy, Economic Impact, Mobile Banking, Blockchain And Cryptocurrencies
Act your age to engage: Field evidence on parent vs. brand extension virality through motivational language
Authors:   , Tincknell Liam
Published: October 2023

This study demonstrates how managers can capitalize on the cost benefits of viral marketing by tailoring social media language to extensions and parent brands. Literature suggests that extensions and parent brands should use the same social media strategy and that establishing fit between extensions and parent brands, rather than fit with consumers, should be the focus of brand managers. We address these gaps by analyzing over 40,000 tweets made by 26 Google-branded Twitter accounts (e.g., @google, @gmail). Results show that for young brand extensions (vs. parent brands), the use of locomotion (vs. assessment) language increases engagement due to regulatory fit.
GAS-KINETIC STATE OF BOTTOM-HOLE PART OF COKING COAL FORMATION AND GEOMECHANICAL PROCESSES IN UNDERWORKED ROCK MASSIF
Authors: Шинкевич М.В.
Published: October 2023

Доля коксующегося угля в общих запасах каменных углей в России составляет ~50 %. Предлагаемый алгоритм расчета метановыделения из угля подходит к коксующимся углям всех марок при их добыче. Согласно оценке величин напряжений, в массиве горных пород и шагов обрушений основной и непосредственной кровли определены параметры сводообразования пород кровли и зоны разгрузки пласта коксующегося угля впереди очистного забоя. Определено распределение метана по формам существования впереди очистного забоя, в том числе и образование свободного метана.

The share of coking coal in the total reserves of coal in Russia is about 50%. The proposed algorithm for calculating methane release from coal is suitable for all grades of coking coals during its underground mining. According to the assessment of stress values, in the rock mass and the collapse steps of the main and direct roofs, the parameters of the roof rock arch formation and the discharge zone of the coking coal formation ahead of the face were determined. The distribution of methane by forms of existence ahead of the treatment face was determined, including the formation of free methane.
An Assessment of the Importance of Vocabulary in English Language Study to Vietnamese Learners
Authors: Nguyen Thi Nhung
Published: October 2023

The aim of this paper is to assess the importance of vocabulary in English language study for Vietnamese learners. This paper summarises 35 scientific papers on the importance of vocabulary in English study in Vietnam. The paper first reviewed current status of vocabulary of Vietnamese learners. Next, the assessment of the importance of vocabulary in English language teaching and testing was fully discussed in Vietnam. Finally, we finished this review by providing suggestions for vocabulary learning in Vietnam. It was found that vocabulary play a very important role in English language study in Vietnam. In addition, this review also finds it important for Vietnamese students to learn English as a Foreign Language (EFL) and for teachers to understand the conditions necessary for vocabulary learning in order to improve vocabulary learning and teaching.

Keywords: Assessment, Importance, Vocabulary, English language study, Vietnam.
Acute Onset Peripheral Neuropathy in a Patient with Scrub Typhus
Authors: Gandhi Pankaj , Nagori Yunus
Published: October 2023

The neurological complications of scrub typhus can have a wide spectrum of presentations involving both central and peripheral nervous system, meningoencephalitis and meningitis being the most common. Involvement of the peripheral nervous system in scrub infection is not commonly reported, here we present a case of A 70-year-old male diagnosed with scrub typhus fever and presented with peripheral neuropathy. Duloxetine and methyl cobalamin combination along with gabapentin were used for management and the patient was partially improved gradually over a period of six days.

Keywords: scrub typhus, scrub infection, scrub typhus fever, orientia tsutsugamushi.
Perspectives of Online News Media on Extreme Poverty and Regional Budget Policy Response
Authors: Indiahono Dwiyanto , Satyawan Darmanto Sahat
Published: October 2023

A report of residents living in extreme poverty level in Banyumas Regency required local government’s response through Extreme Poverty Reduction Program. Such poverty alleviation program consequently necessitated swift provision from the regional budget (Anggaran Pendapatan dan Belanja Daerah/APBD). On the other hand, no budget had been allocated for the program during the budget year and the APBD was limited. The purpose of this study is to examine the responses of regional budget policy to the extreme poverty issue based on online news articles related to the subject. The study was conducted using content analysis methods and systematic literature reviews. The results show that the Banyumas government's response in addressing extreme poverty issue is relatively satisfactory. The local government responded with a regional budget policy by funding the program through Unexpected Expenditure (Belanja Tidak Terduga/BTT) budget item. Part of APBD, BTT was allocated as non-cash extreme poverty alleviation expenditure, while cash social assistance was to be sought to from the provincial and central government. Local governments do not have adequate budgetary capacity to independently finance extreme poverty alleviation programs and therefore require major support from the central and/or provincial government. A synergy between local, provincial and central governments is thus needed to better manage regional extreme poverty alleviation initiatives.
利用2016年TASSE實驗期間X-band雷達資料反演及分析雨滴粒徑分布特性
Authors: 曾昭誠 曾昭誠 , 林沛練 林沛練 , Pay-Liam Lin 陳台琦 , 鍾高陞 鍾高陞
Published: October 2023

雨滴粒徑分布(DSD)可呈現降雨過程中碰撞、結合及分裂的微物理特徵，近地表的DSD可由雨滴譜儀觀測獲得，空間中搭配雙偏極化雷達高時空解析度的觀測，使用相關公式即可反演三維的DSD參數。DSD參數反演可使用由形狀參數(μ)、斜率參數(λ)及截距參數(N_0 )組成的Gamma DSD；雙偏極化雷達參數亦可由撞擊式雨滴譜儀(JWD)觀測的Gamma DSD模擬，兩者需由μ-λ約束關係做連結。以往使用長期統計之DSD，但DSD的特徵因時、空、降雨類型不同而改變，測試不同DSD觀測有助於改善雷達反演DSD參數的成效。

本研究使用2016雙北都會區夏季暴雨觀測預報實驗(TASSE)期間，佈署於五股的移動式X波段雙偏極化都卜勒雷達(TEAM-R)及新店、翡翠水庫的JWD。反演所需的μ-λ約束關係使用本個案於翡翠水庫JWD的觀測資料及Brandes (2003)的統計；另測試直接擬合以JWD計算之DSD參數、雙偏極化雷達參數的關係式，討論三種方法反演對流胞DSD三維結構的成效，結果以μ-λ約束關係的反演結果較佳，直接擬合式無法表現合理約束關係。反演結果在淺對流有較窄的DSD及較小的均值粒徑(D_m )、較低的雨滴濃度(N_w )；深對流有較寬的DSD、較淺對流高數百至數千倍的D_m 、 N_w；層狀降雨有偏窄的DSD、介於深對流及淺對流間的N_w 、 D_m。使用μ-λ約束關係得到雲物理特徵一致，且使用實驗期間的地面DSD觀測能得到更好的結果。

 

The microphysical process in precipitation contains collision, coalescence, and break. The Polarimetric Radars can obtain the 3-D structure of the precipitation system, and the disdrometers obtain the drop size distribution (DSD) characteristic on the ground. The 3-D DSD structure could be retrieved through polarimetric variables and DSD statistics data. The constrained relation between the shape (μ) and slope (λ) is necessary to retrieve the Gamma DSD from Z_dr and K_dp. The DSD varies from case to case. Therefore, understanding the variety of DSD is helpful to improve the accuracy of DSD retrieved by radar.

The TEAM-R radar and Impact Disdrometer (JWD) data were collected in 2016 TASSE. Two constrain relations were applied: Brandes in 2003, and the JWD statistics during the TASSE. A third approach is directly fitting the Gamma DSD with the polarimetric variables to retrieve the DSD. Because the lack of constraint, the fitting method is unable to retrieve reasonable DSD at large Z_dr. The relatively smaller concentration and drop diameter were found in the shallow convections, whereas higher concentrations were found in deep convection through the convective core.

 
邁向公平正義的教育
Authors: 高家斌 高家斌
Published: October 2023

為推廣教育111理念，本書以邁向公平正義的教育為主題，並分為公平正義的教育理念篇、公平正義的教育發展篇、公平正義的教育實踐三大篇，每一篇中都各有相關的主題文章，合計13篇專題文章。專書內容包含：教育公義的追尋：從一個都不少談起、公平正義的教育理念及實踐：以臺北市認助清寒學生為例、從理論的觀點看教育的公平與正義：「一師一卓越」與「教育111標竿學校」、從學習的保障觀點看融合教育如何落實教育的公平與正義、臺北市中小學初任校長導入班實施成效之研究、從大學社會責任論高教深耕計畫執行成效、落實學校社會責任的起點：教師社會正義領導者的信念、困境與實行原則、國民小學組織正義指標建構之研究、教育中立內涵與實踐策略之探析、以學習領導促進教育公義的實踐、幼兒園領導的公平正義實踐策略之探究、從幼兒就學補助論教育公平的實踐、教育公平正義的實踐：從高中跨領域專題課程出發。本書各篇文稿均經過雙匿名審查，並能依專業審查意見進行修正，可讀性高。各篇論文內容豐富，見解精闢，兼具理論與實務，且能符應邁向公平正義教育之潮流與趨勢，並能符應實踐教育111的理念，對於教育研究人員與實務工作者而言，值得加以參考與研讀。

作者簡介

吳清山　國立暨南國際大學教育政策與行政學系榮譽講座教授．臺北市立大學教育行政與評鑑研究所名譽教授．社團法人111教育發展協進會理事長

黃國忠　臺北市立大學教育行政與評鑑研究所博士生、臺北市政府教育局學安室主任

曾燦金　前臺北市教育局局長

諶亦聰　臺北市動物園園長

石文南　臺北市政府教育局認助清寒學生基金會執行長

張健裕　臺北市政府教育局認助清寒學生基金會推廣組組長

林雅婷　臺北市南港區成德國民小學教師

鄭崇趁　國立臺北教育大學教育經營與管理學系教授．社團法人111教育發展協進會常務理事

鄭依萍　國立彰化師範大學公民教育與公共事務學系助理教授

林雍智　亞洲大學幼兒教育學系助理教授

劉春榮　臺北市立大學名譽教授

林海清　中臺科技大學文教事業經營管理研究所講座教授

張文權　國立臺東大學師資培育中心助理教授

范熾文　國立東華大學教育行政與管理學系教授

楊孟璇　新北市中和區興南國民小學教師

游子賢　中華民國中小學校長協會專案助理

白玉玲　臺北市大同區國民小學校長

黃旭鈞　臺北市立大學教育行政與評鑑研究所副教授．社團法人111教育發展協進會常務理事

高家斌　南臺科技大學幼兒保育系教授

蘇玲慧　國立臺北教育大學博士後研究員

黃盈斐　南臺科技大學幼兒保育系兼任助理教授

孫良誠　國立清華大學幼兒教育學系副教授

黃世隆　臺北市立大學教育行政與評鑑研究所博士．中華未來學校教育學會理事
The Holy Spirit’s Eternal Procession in the Book of Revelation: Theological Interpretation in Pro-Nicene Perspective
Authors: Smith Brandon D.
Published: October 2023

Interpreting the book of Revelation requires careful exegesis on its own, but exegetical issues multiply when one attempts to draw out its pneumatology. Through theological interpretation and pro-Nicene categories, this article will demonstrate one way to understand the book of Revelation’s contribution to an articulation of the Holy Spirit’s eternal procession.
Hands-on Hypoxia: Engaging High School Educators in the science behind Marine Microbial Dynamics in Hypoxic Coastal Areas Through Field and Classroom Experiences
Authors: Kelly Kyla J. , Kast Dieuwertje J. , Schiksnis Cara A. , Thrash J. Cameron
Published: October 2023

The University of Southern California’s (USC) Joint Educational Project’s STEM Education Programs hosted a three-day summer workshop focused on marine microbiology and coastal deoxygenation for high school educators. To increase ocean literacy in high school students from Title I schools, topical marine science research was translated into four lesson plans appropriate for classrooms that teach biology and environmental science. The lesson plans focus on how marine microbes affect and are affected by the dissolved oxygen content of seawater but covered diverse oceanography topics including microbial ecology, nutrient cycling, physical ocean dynamics, and climate change. This education framework was designed to promote and facilitate hands on discovery-based learning and making observations about the natural world. The workshop and lesson plan development were executed in partnership with faculty and graduate students researching marine microbes and oceanography from USC’s Marine and Environmental Biology department to provide scientific expertise on the subject matter. At the workshop, educators were guided through each lesson plan and given classroom sets of materials to complete each of the experiments in their own classrooms. Educators also had the opportunity to experience the academic research process at both USC and the Wrigley Institute of Environmental Studies on Catalina Island, California. Teachers valued this interactive experience to learn from professional scientists and STEM educators. They left the workshop equipped with the knowledge and confidence to teach these marine microbiology and biogeochemistry concepts in their classrooms.
La mayor resiliencia de la economía española frente al área del euro en 2023: el papel de la composición sectorial
Authors: Fernández Cerezo Alejandro , Kataryniuk Iván , Rodríguez Francisco José
Published: October 2023

Motivación

En un contexto de mayor debilidad de la actividad global y del área del euro, en el tiempo transcurrido de 2023 la economía española ha mostrado una resiliencia notable en comparación con otras economías europeas. El objetivo de este artículo es ilustrar algunos de los factores que explican esta mayor fortaleza.

Ideas principales

•Las diferencias entre la composición sectorial de la economía española y la del área del euro justificarían una parte del mayor dinamismo reciente de la actividad en nuestro país.

•La exposición comercial de España a China —cuya desaceleración reciente es uno de los principales factores de la ralentización económica global— es menor que la de otras economías del área del euro.

•El mantenimiento de un mejor comportamiento de la economía española en relación con la del área del euro en los próximos trimestres dependerá, entre otros factores, de cómo se traslade el menor crecimiento esperado de las manufacturas a los servicios o de si se materializa una pérdida de dinamismo del turismo.
Menilik Pembinaan Pemuda Terhadap Tanggung Jawab Melayani di Gereja Pada Masa Kini
Authors: Blegur Romelus , Sari Linda Nung , Doni Doni , Pini Pini
Published: October 2023

This Community Service activity aims to look at the responsibility of youth in the church today, because the church is facing a crisis in the role of youth as figures who are expected to make new breakthroughs in the church facing the challenges of progress in today. This situation was also experienced by GKII Gloria Ganjang Kanan, Tanah Pinoh with the decline in the active role of youth in ecclesiastical services due to the influence of the present era with the spread of a strong digital culture that attracts the tastes of young people. To respond to this, coaching was carried out for the youth of GKII Gloria Ganjang Kanan, Tanah Pinoh to provide an understanding of the current situation and its challenges, as well as increase their awareness and responsibility to the church. This activity uses the lecture method through prepared materials and interactions to deepen the understanding of the youth. The result of this activity is that the formation of youth seems effective in fostering their awareness and responsibility towards the church. This can be seen through the youth's understanding of the material presented and as a follow-up they also actively participate in service in the church and are responsible for the duties of the ministry given.Keywords: church; responsibility; Christian youth; today; CoachingAbstrakKegiatan Pengabdian kepada Masyarakat ini bertujuan menilik tanggung jawab pemuda di gereja zaman now, sebab gereja tengah menghadapi krisis akan peran pemuda sebagai figur yang diharapkan dapat membuat terobosan baru dalam gereja menghadapi tantangan kemajuan di zaman now. Situasi tersebut pun turut dialami oleh GKII Gloria Ganjang Kanan, Tanah Pinoh dengan menurunnya peran aktif pemuda dalam pelayanan gerejawi oleh karena pengaruh zaman now dengan merebaknya budaya digital yang kuat menggaet selera para pemuda. Untuk menyikapinya, maka dilakukan pembinaan kepada para pemuda GKII Gloria Ganjang Kanan, Tanah Pinoh guna memberikan pemahaman tentang situasi zaman now dan tantangannya, serta meningkatkan kesadaran dan tanggung jawab mereka terhadap gereja. Kegiatan ini menggunakan metode ceramah melalui materi yang disiapkan dan interaksi guna memperdalam pemahaman para pemuda. Hasil dari kegiatan ini adalah, bahwa pembinaan terhadap pemuda tampak efektif untuk memupuk kesadaran dan tanggung jawab mereka terhadap gereja. Hal tersebut tampak melalui pemahaman pemuda tentang materi yang disampaikan dan sebagai tindaklanjutnya mereka pun turut aktif dalam pelayanan di gereja dan bertanggung jawab atas tugas-tugas pelayanan yang diberikan.Kata Kunci: gereja; tanggung jawab; pemuda Kristen; zaman now; pembinaan
Psychological approaches to treating visual hallucinations in Lewy body dementias
Authors: Rowley Claire , Cook Julia
Published: October 2023

Visual hallucinations are a common and often distressing experience for those diagnosed with a Lewy body dementia, affecting as many as 80% of those diagnosed. This article explores how psychological approaches may provide an effective alternative to the limited medications that are currently available as a treatment. Current research suggests that psychoeducation, modification of appraisals and validation have promising results. However, this research is still in its infancy and needs to be explored further.
The Importance of Biomarkers in the Diagnosis and Follow-Up of the Celiac Disease
Authors: GÜMÜŞ Meltem , YORULMAZ Alaaddin , KİLİM Esra , GÜMÜŞTEKİN Reyhan , ERGANİ Anna Carina , EMİROĞLU Halil
Published: October 2023

Aim: In the present study, the purpose was to investigate the clinical significance, diagnostic capabilities, relationships, and correlations of inflammation-based biomarkers before and after treatment in children with Celiac Disease.
Methods: The study was conducted by retrospectively evaluating the files of patients who were diagnosed and followed up in the Department of Pediatric Gastroenterology of Selçuk University between January 2011 and January 2023. The study was completed with 202 Celiac Disease patients who were diagnosed according to the criteria of the European Pediatric Gastroenterology, Hepatology, and Nutrition Community and 160 healthy follow-ups. In case of clinical or laboratory suspicion, serological tests such as positive Tissue Transglutaminase Antibody and Anti-Endomysium values and the histopathological examination of the endoscopic tissue sample findings consistent with Celiac Disease were evaluated.
Results: There were 122 (56.7%) girls and 80 (54.4%) boys in the patient group and 93 (43.3%) girls and 67 (45.6%) boys in the control group. The most common intestinal complaint was abdominal pain in 49 (22.3%) patients. Gluten-free diet treatment was started after the diagnosis. The values of the patients at the time of diagnosis, in the 6th month after the diet, and the values of healthy control patients were compared. A weak and positive correlation was found between NLR, RPO, RLO levels, and age, body weight, and height in the correlation analysis. The ROC curve for hematological biomarkers was used to evaluate the level of additional diagnostic support in Celiac Disease patients.
Conclusion: After a gluten-free diet, symptoms regress, and the development of more serious celiac-related damage can be prevented. This suggests that NLR, RLR, PLO, SII, HRO, and PNI formulas, which are used in many inflammatory conditions and obtained from routine hemogram parameters, can be used to determine dietary compliance in Celiac Disease patients during their follow-ups.
Different Approach on our Cells and the Use of CRISPR/Cas 9 Technology: Super Gene'ethic
Authors: KÖKSOY Hale , AMEEN AL QADRİ Mohammed Saleh , KARAKAYA Serap , BACAK Pelin , YÜKSEL Elif Senanur , KOÇER Şengül , KAV Emine , DEMİR Sümeyra , DEMİREL Ece , AKKAYA Himmet , AKMEŞE Ayşe Nur , TAŞKAYA Ayşenur
Published: October 2023

Aims: CRISPR/Cas9, a revolutionary genome editing tool derived from a bacterial system, has transformed molecular biology research, enabling precise and versatile modifications to the genome. This study surveyed 300 participants, including instructors, second-year medical students, and patient relatives from Selcuk University Faculty of Medicine, to assess their knowledge, attitudes, and ethical perspectives on gene editing.
Methods: A comprehensive survey was conducted, and the participants' demographics were correlated with their responses. Statistical analysis was performed using SPSS 22.0.
Results: The survey revealed significant differences (p<0.05) in attitudes based on gender, age, and participation groups. The age group of 18-29 exhibited the highest participation rate (57.3%), while the age group of 60-65 had the lowest (1%). Approximately 50.3% of participants reported no prior knowledge of CRISPR/Cas9, and 64.3% were university graduates. Obtaining approval from ethics committees was considered crucial by 151 respondents for commencing CRISPR/Cas9 research. Interestingly, 63.3% showed eagerness for genetically modified plants and animals, while only 9% expressed interest in studies related to eternal youth. Additionally, 88% found gene editing studies conflicting with their beliefs.
Conclusions: CRISPR/Cas9 holds great promise for biomedicine and healthcare but necessitates enhanced public awareness and informed decision-making. The study highlights the importance of promoting informed discussions on the ethical implications of CRISPR/Cas9 to address the concerns and perceptions of various demographics. These valuable insights contribute to the ongoing discourse on the impact of CRISPR/Cas9 on society.
ISOBARIC LEVOBUPIVACAINE VERSUS HYPERBARIC BUPIVACAINE IN PREGNANT WOMEN UNDERGONE CESAREAN SECTIONS: A RANDOMIZED CONTROLLED TRIAL
Authors: AMJAD A , SADIA H , SAAD M , ALI A , NAEEM A , NAEEM H , AHMED M
Published: October 2023

To compare isobaric levobupivacaine versus hyperbaric bupivacaine for pregnant women who have undergone cesarean sections. In this randomized controlled trial, 70 patients with ASA physical status I-II, scheduled i.e for elective lower segment cesarean section (LSCS), were divided into two equal-sized groups (n = 35 each). Group A was treated with 2.5 ml of isobaric levobupivacaine, while Group B was treated with 2.5 ml of hyperbaric bupivacaine. Both groups' sensory and motor block features were evaluated using the pinprick test and the Bromage scale. Additionally, any instances of hypotension and potential side effects were meticulously recorded. Subsequently, the collected data underwent statistical analysis employing appropriate tests. The initiation of sensory blockage was observed to be slower, and the regression duration for two segments was extended while using isobaric levobupivacaine (p < 0.001). Nevertheless, it generated sufficient surgical anesthetic with a reduced duration of motor blocking and fewer side effects compared to hyperbaric bupivacaine.  This study concludes that single-shot spinal anesthesia with different local anesthetics is effective for prompt surgical anesthesia induction in elective cesarean section procedures. Among these options, levobupivacaine is a superior choice due to its smaller duration of motor block, reduced side effects, and lower risk of hypotension, making it particularly well-suited for such procedures.