bluuebunny/crossref_metadata_2025 huggingface dataset:
Physics in the Machine: Integrating Physical Knowledge in Autonomous Phase-Mapping
Authors: Kusne A. Gilad , McDannald Austin , DeCost Brian , Oses Corey , Toher Cormac , Curtarolo Stefano , Mehta Apurva , Takeuchi Ichiro
Published: February 2022

Application of artificial intelligence (AI), and more specifically machine learning, to the physical sciences has expanded significantly over the past decades. In particular, science-informed AI, also known as scientific AI or inductive bias AI, has grown from a focus on data analysis to now controlling experiment design, simulation, execution and analysis in closed-loop autonomous systems. The CAMEO (closed-loop autonomous materials exploration and optimization) algorithm employs scientific AI to address two tasks: learning a material system’s composition-structure relationship and identifying materials compositions with optimal functional properties. By integrating these, accelerated materials screening across compositional phase diagrams was demonstrated, resulting in the discovery of a best-in-class phase change memory material. Key to this success is the ability to guide subsequent measurements to maximize knowledge of the composition-structure relationship, or phase map. In this work we investigate the benefits of incorporating varying levels of prior physical knowledge into CAMEO’s autonomous phase-mapping. This includes the use of ab-initio phase boundary data from the AFLOW repositories, which has been shown to optimize CAMEO’s search when used as a prior.
Propagation Properties of a Twisted Hermite-Gaussian Correlated Schell-Model Beam in Free Space
Authors: Liu Leixin , Wang Haiyun , Liu Lin , Dong Yiming , Wang Fei , Hoenders Bernhard J. , Chen Yahong , Cai Yangjian , Peng Xiaofeng
Published: February 2022

We introduce a novel type of twisted partially coherent beams with a nonconventional correlation function, named the twisted Hermite-Gaussian correlated Schell-model (THGCSM) beam. The condition that a twist phase can be imposed on a partially coherent beam is addressed for Schell-model fields endowed with rectangular symmetry. Further, the analytical formula for the THGCSM beam propagating in free space has been derived with the help of the generalized Collins formula. The propagation properties, such as the spectral density and the spectral degree of coherence (SDOC) of the THGCSM beam, also have been studied in detail by some numerical examples. The numerical results show that the twist phase plays a role in resisting beam splitting, caused by the correlation structure, and induces the rotation of the distribution of the SDOC on propagation. Moreover, it is interesting to find that when the beam carries a twist phase, this will endow the beam the ability to maintain its distribution of the SDOC on propagation and enhance the self -reconstruction capability of the SDOC. Our results may provide new insights into nonconventional partially coherent beams with twisted phase and may be useful in some applications, such as optical communications and information recovery.
Establishment of a Live-Imaging Analysis for Polarized Growth of Conchocelis in the Multicellular Red Alga Neopyropia yezoensis
Authors: Hiwatashi Yuji , Shimada Mizuho , Mikami Koji , Takada Nagisa
Published: February 2022

A wide range of tip-growing cells in plants display polarized cell growth, which is an essential cellular process for the form and function of individual cells. Understanding of the regulatory mechanisms underlying tip growth in terrestrial plants has improved. Cellular processes involved in tip growth have also been investigated in some algae species that form filamentous cells, but their regulatory mechanisms remain unclear. In the macro red alga Neopyropia yezoensis, for which genome information has recently been released, the conchocelis apical cell exhibits tip growth and forms a filamentous structure. Here, we report a live-imaging technique using high-resolution microscopy to analyze the tip growth and cell division of N. yezoensis conchocelis. This imaging analysis addressed tip growth dynamics and cell division in conchocelis apical cells. The directionality and tip growth expansion were disrupted by the application of cytoskeletal drugs, suggesting the involvement of microtubules (MTs) and actin filaments (AFs) in these processes. A growing apical cell mostly contained a single chloroplast that moved toward the expanding part of the apical cell. Drug application also inhibited chloroplast movement, implying that the movement may be dependent on the cytoskeleton. The study determined that live-imaging analysis is a versatile approach for exploring the dynamics of tip growth and cell division in N. yezoensis conchocelis, which provides insights into the regulatory mechanisms underlying cellular growth in multicellular red algae.
A Brief Overview of Gravity Wave Retrieval Techniques From Observations
Authors: Sakib Md Nazmus , Yiğit Erdal
Published: February 2022

Atmospheric gravity waves (GWs) are important in driving the middle and upper atmosphere dynamics on Earth. Here, we provide a brief review of the most common techniques of retrieving gravity wave activity from observations. Retrieval of gravity wave activity from observations is a multi-step process. First, the background fields have to be removed as the retrieval of the wave activity highly depends on this. Second, since a broad spectrum of internal waves contributes to atmospheric fluctuations, the contribution of GWs has to be extracted carefully. We briefly discuss the strengths, limitations/barriers, and applications of each technique. We also outline some future research questions to improve the treatment of these wave extraction methods.
Assessing the Effectiveness of Providing Live Black Soldier Fly Larvae (Hermetia illucens) to Ease the Weaning Transition of Piglets
Authors: Ipema Allyson F. , Gerrits Walter J. J. , Bokkers Eddie A. M. , van Marwijk Manon A. , Laurenssen Bjorge F. A. , Kemp Bas , Bolhuis J. Elizabeth
Published: February 2022

Weaning is a stressful event for piglets, involving substantial changes to their nutritional and social environment. Providing edible enrichment around weaning may ease the weaning transition by increasing pre-weaning feed intake and improving post-weaning performance, health, behavior, and affective state. In this study, we investigated the effects of providing live black soldier fly larvae (BSFL) as edible enrichment pre- and/or post-weaning. Pre-weaning, piglets received either only creep feed (Pre-C, n = 14 litters) or creep feed and live BSFL (Pre-L, n = 15 litters) ad libitum, and post-weaning piglets either had no access to live BSFL (Post-C, n = 24 pens) or they could rotate tubes that released BSFL (Post-L, n = 24 pens) at levels up to 20% of their expected daily dry matter intake, resulting in treatments CC, CL, LC, and LL. No interaction between pre- and post-weaning treatment was found for any of the measured parameters. Before weaning, Pre-L piglets preferred to interact with larvae over creep feed, and Pre-C piglets interacted more with creep feed than Pre-L piglets. Total time spent on feed-directed behaviors did not differ. Continuous larvae provisioning increased caecum length and proximal stomach digesta pH, while it decreased the passage of glucose and fluorescein isothiocyanate through the colon wall on d3 post-weaning (CC vs. LL, n = 12 piglets/treatment). Post-weaning diarrhea and final body weight were not affected by treatment. After weaning, Pre-C piglets tended to eat more and grew marginally faster than Pre-L piglets. Post-C piglets spent more time eating and had a higher feed intake post-weaning than Post-L piglets. Based on home-pen behavioral observations, Post-L piglets actively explored and ate the larvae. Post-C piglets spent more time on exploring the environment and nosing pen mates, and they spent more time on manipulating pen mates on d8 and played more on d8 & 15 compared to Post-L piglets. Piglet responses to a novel environment and an attention bias test on d4 & 5 post-weaning were not influenced by larvae provisioning. In conclusion, pre-weaning larvae provisioning did not improve pre-weaning feed intake and post-weaning performance, however post-weaning larvae provisioning did benefit piglet behavior as less manipulation of pen mates was observed.
Parameter-Matching Algorithm and Optimization of Integrated Thermal Management System of Aircraft
Authors: Wang Ri , Dong Sujun , Jiang Hongsheng , Li Peiru , Zhang Hainan
Published: February 2022

The integrated thermal management system of aircraft is essential to maintain a suitable environment for the cabin crew and devices. The system is composed of the air-cycle refrigeration subsystem, the vapor-compression refrigeration subsystem, the liquid-cooling subsystem and the fuel-cycle subsystem, which are coupled with each other through heat exchangers. Due to the complex structure and large number of components in the system, it is necessary to design a corresponding parameter-matching algorithm for its special structure and to select the appropriate optimization design method. In this paper, the structure of an integrated thermal management system is analyzed in depth. A hierarchical matching algorithm of system parameters was designed and realized. Meanwhile, a sensitivity analysis of the system was performed, where key parameters were selected. Besides, a variety of optimization algorithms was used to optimize the design calculations. The results show that the particle swarm optimization and genetic algorithm could effectively find the global optimal solution when taking the fuel penalty as the objective function. Furthermore, the particle swarm optimization method took less time.
Review of the Analytical Methods Based on HPLC-Electrochemical Detection Coupling for the Evaluation of Organic Compounds of Nutritional and Environmental Interest
Authors: Maio Monica , Di Fiore Cristina , Iannone Alessia , Carriera Fabiana , Notardonato Ivan , Avino Pasquale
Published: February 2022

This review would like to show the state of the art regarding the coupling of High-Performance Liquid Chromatography (HPLC) with Electrochemical Detection (ED). Since a universal detector for HPLC is not available, the electrochemical detection methods, thanks to their versatility and specificity, are competitive with respect to the detectors currently used. The papers present in literature on HPLC-ED technique are analyzed and discussed: for example, they regard the development of analytical determinations of resveratrol, rosmarinic acid, aromatic heterocyclic amines and glyphosate in food matrices such as meat, aromatic plants, vegetables, fruit and tomato juices. These papers show that electrochemical sensors used as detectors for HPLC can offer better sensitivity values than other detectors. Furthermore, the use of specific working potentials allows avoid matrix interferences to be avoided by almost exclusively determining the analytes of interest. It should be underlined that HPLC-ED methods have a selectivity that allows for limitation of the sample preparation and clean-up procedures to a minimum, making them quick and easy to apply. In addition, these methods offer advantages such as the possibility of direct analysis, that derivatization is often not necessary, the cost-effectiveness of the instrumentation and the possibility of regenerating the electrodes which allows numerous analyses in succession.
What Participation Creates in Experimental Design Practices. The Case of a Mobile Third Place Built in a Retirement Home
Authors: Royer Marine
Published: February 2022

This article explores the rise of a new generation of practices combining architecture, design, and art, trying to answer the transition issues faced by society. It develops original operating procedures, including public participation. In doing so, those so-called “specialised” professions expand their sphere of operation and incorporate more immaterial dimensions and resources. The main objective of the article is an attempt to clarify how participation is embodied in specific intervention methods, within those experimental practices. The article will take as a case study a participatory project taking place in a retirement home and aimed at building a mobile third place that brought together various professionals coming from those experimental practices. The study of the participatory project will outline three devices and methods supporting the participation work, as follows: the use of permanence, the use of the prototype and self-construction, and the conception of ephemeral production. The article suggests that based on their analysis, we can understand what architects and designers “manufacture” through the agency of participation. Or more accurately, what participation “manufactures” in those experimental practices. The main result of the article is that the participatory project is more concerned with the motives and aspirations of the design activity, its methods and processes, its context and socialisation than it is with what would be classically considered as the outcome or result (the work, the realisation, the production, the built).
Exploring the Health Information Management System of Kuwait: Lessons and Opportunities
Authors: Alnashmi Maha , Salman Ahmad , AlHumaidi Hanadi , Yunis Maha , Al-Enezi Naser
Published: February 2022

After studying the professional practices related to the management of medical records in Kuwaiti hospitals, it became utterly evident that there is inadequate understanding about maintaining the health information of patients. This dire situation is further compounded by the absence of official regulations established by the Ministry of Health for hospitals to effectively assess and manage medical records. Through this study, the researchers aimed to assess the medical records system in multiple healthcare settings in Kuwait, comprising government, private, and oil sectors. The study was carried out from May 2019 to July 2020 and used a self-developed, pilot-tested questionnaire measuring various aspects of the medical records management system. A total of 98 participants responded to the survey. The study results revealed that 43% of hospitals were using paper-based medical records, as compared to 53% that used both paper-based and electronic media. Moreover, 40% of hospitals in Kuwait did not adhere to the Ministry of Health policies regarding medical records disposition; instead, they developed their own hospital-based disposition policy. Moreover, the study findings showed that there were clear discrepancies in record retention policies among the participating hospitals, and the duration of record retention varied from 2 years, 5 years, 10 years, and more than 20 years across hospitals in Kuwait. In conclusion, national policies and guidelines need to be established to monitor the medical record systems in Kuwaiti hospitals to further enable better patient care and improve healthcare facilities. Furthermore, it has become indispensable to develop and maintain electronic health records as they constitute an integral part of modern healthcare.
A New Charging Algorithm for Li-Ion Battery Packs Based on Artificial Neural Networks
Authors: Faria João P. D. , Velho Ricardo L. , Calado Maria R. A. , Pombo José A. N. , Fermeiro João B. L. , Mariano Sílvio J. P. S.
Published: February 2022

This paper shows the potential of artificial intelligence (AI) in Li-ion battery charging methods by introducing a new charging algorithm based on artificial neural networks (ANNs). The proposed charging algorithm is able to find an optimized charging current profile, through ANNs, considering the real-time conditions of the Li-ion batteries. To test and validate the proposed approach, a low-cost battery management system (BMS) was developed, supporting up to 168 cells in series and n cells in parallel. When compared with the multistage charging algorithm, the proposed charging algorithm revealed a shorter charging time (7.85%) and a smaller temperature increase (32.95%). Thus, the results show that the proposed algorithm based on AI is able to effectively charge and balance batteries and can be regarded as a subject of interest for future research.
The History and Innovations of Blood Vessel Anastomosis
Authors: Moritz William R. , Raman Shreya , Pessin Sydney , Martin Cameron , Li Xiaowei , Westman Amanda , Sacks Justin M.
Published: February 2022

Surgical technique and technology frequently coevolve. The brief history of blood vessel anastomosis is full of famous names. While the techniques pioneered by these surgeons have been well described, the technology that facilitated their advancements and their inventors deserve recognition. The mass production of laboratory microscopes in the mid-1800s allowed for an explosion of interest in tissue histology. This improved understanding of vascular physiology and thrombosis laid the groundwork for Carrel and Guthrie to report some of the first successful vascular anastomoses. In 1916, McLean discovered heparin. Twenty-four years later, Gordon Murray found that it could prevent thrombosis when performing end-to-end anastomosis. These discoveries paved the way for the first-in-human kidney transplantations. Otolaryngologists Nylen and Holmgren were the first to bring the laboratory microscope into the operating room, but Jacobson was the first to apply these techniques to microvascular anastomosis. His first successful attempt in 1960 and the subsequent development of microsurgical tools allowed for an explosion of interest in microsurgery, and several decades of innovation followed. Today, new advancements promise to make microvascular and vascular surgery faster, cheaper, and safer for patients. The future of surgery will always be inextricably tied to the creativity and vision of its innovators.
Controlling Cell Trafficking: Addressing Failures in CAR T and NK Cell Therapy of Solid Tumours
Authors: White Lydia G. , Goy Hannah E. , Rose Alinor J. , McLellan Alexander D.
Published: February 2022

The precision guiding of endogenous or adoptively transferred lymphocytes to the solid tumour mass is obligatory for optimal anti-tumour effects and will improve patient safety. The recognition and elimination of the tumour is best achieved when anti-tumour lymphocytes are proximal to the malignant cells. For example, the regional secretion of soluble factors, cytotoxic granules, and cell-surface molecule interactions are required for the death of tumour cells and the suppression of neovasculature formation, tumour-associated suppressor, or stromal cells. The resistance of individual tumour cell clones to cellular therapy and the hostile environment of the solid tumours is a major challenge to adoptive cell therapy. We review the strategies that could be useful to overcoming insufficient immune cell migration to the tumour cell mass. We argue that existing ‘competitive’ approaches should now be revisited as complementary approaches to improve CAR T and NK cell therapy.
Do Children and Adolescents with Overweight or Obesity Adhere to the National Food-Based Dietary Guidelines in Greece?
Authors: Georgiou Alexandra , Androutsos Odysseas , Chouliaras Giorgos , Charmandari Evangelia
Published: February 2022

Childhood obesity increases the risk for metabolic disorders, but is also related to nutritional deficiencies, such as anemia and hypovitaminosis D. Although children/adolescents with overweight/obesity may have higher energy intake, their diet quality and diversity may be low. The present study aimed to evaluate the consumption of foods against the national food-based dietary guidelines in children and adolescents with overweight or obesity in Greece. Sociodemographic, anthropometric and lifestyle data were collected from a sample of 1467 children 2–18 years old (962 obese, 505 overweight, 51.2% females) in 2014–2017. The results of this study show that the consumption of dairy products, fruit, vegetables, legumes and fish by children/adolescents with overweight or obesity was lower than the national recommendations (ranging from a minimum of 39.5% for fish, to a maximum of 75.5% for cereal/potato/rice). Only the consumption of meat/poultry was found to exceed the national recommendation (estimated coverage of 131.3%). Moreover, a large proportion of participants regularly consumed various unhealthy foods/beverages. The present findings indicate that the majority of children/adolescents with overweight/obesity do not comply with the national food-based dietary guidelines in Greece. The implementation of new strategies to promote healthy diets among children/adolescents with overweight/obesity are urgently required.
You Cannot Hit Snooze on OSA: Sequelae of Pediatric Obstructive Sleep Apnea
Authors: Thomas Selena , Patel Shefali , Gummalla Prabhavathi , Tablizo Mary Anne , Kier Catherine
Published: February 2022

Pediatric obstructive sleep apnea (OSA) has been shown to not only affect the quality of sleep, but also overall health in general. Untreated or inadequately treated OSA can lead to long-term sequelae involving cardiovascular, endothelial, metabolic, endocrine, neurocognitive, and psychological consequences. The physiological effects of pediatric OSA eventually become pathological. As the complex effects of pediatric OSA are discovered, they must be identified early so that healthcare providers can be better equipped to treat and even prevent them. Ultimately, adequate management of OSA improves overall quality of life.
Evaluation of Children Caries Risk Factors: A Narrative Review of Nutritional Aspects, Oral Hygiene Habits, and Bacterial Alterations
Authors: Butera Andrea , Maiorani Carolina , Morandini Annalaura , Simonini Manuela , Morittu Stefania , Trombini Julia , Scribante Andrea
Published: February 2022

Dental caries is one of the most common diseases—both in adults and children—that occurs due to the demineralization of enamel and dentine by the organic acids formed from bacteria present in dental plaques through anaerobic metabolism of dietary sugars. The aim of this article is to provide a guideline to assess the risk of caries by looking for the main factors involved. Literature research was performed for studies that analyzed the factors most involved in the development of child caries, such as poor oral hygiene, bad eating habits (or food disorders), and an alteration of the oral bacterial flora—with an increase of Streptococci spp., Lactobacilli spp., Candida albicans, Cryptococcus neoformans, and Candida sake. It is therefore essential to assess the risk of caries in children, based on the assessment of risk factors, in order to be able to establish preventive and/or therapeutic approaches that will reduce or stop the development of dental caries. The use of fluoride products, products made from casein phosphopeptide-amorphous calcium phosphate, substituted zinc biomimetic hydroxyapatite products, or products containing self-assembling oligopeptide SAP-P11-4 are useful. In terms of the clinical approach, a communicative approach should be added to learn about the eating habits and the oral hygiene habits of the child and parents; in addition, the use of a simple method to frame the factors involved, and subsequently establish the risk of carious lesions in the child, allows the reduction of the DMFT (Decayed Missing Filled Teeth) or ICDAS (International Caries Detection and Assessment System) index on large scales.
Neurodevelopmental Outcomes in Tetralogy of Fallot: A Systematic Review
Authors: Kordopati-Zilou Kalliopi , Sergentanis Theodoros , Pervanidou Panagiota , Sofianou-Petraki Danai , Panoulis Konstantinos , Vlahos Nikolaos , Eleftheriades Makarios
Published: February 2022

BACKGROUND: Tetralogy of Fallot (TOF) represents between 7 and 10% of the total cases of congenital heart defects (CHD) and is estimated to be the most common cyanotic CHD, requiring medical or surgical intervention within the first year of life. Current advances in prenatal screening and fetal echocardiography led to increased rates of prenatal diagnosis of TOF. Furthermore, improvements in initial medical care, surgical repair, and long-term care are associated with excellent long-term survival until adulthood. Consequently, issues of morbidity have come under the spotlight, specifically neurodevelopmental and psychiatric adverse outcomes, which affect the quality of life of TOF survivors. METHOD: This study is a systematic review of English articles, using PUBMED and applying the following search terms, Tetralogy of Fallot, neurodevelopment, autism, cerebral palsy, attention-deficit hyperactivity disorder. Data were extracted by two authors. RESULTS: Most researchers suggest that TOF survivors score lower in neurodevelopmental tests than healthy populations of the same age and are in danger of neurodevelopmental impairments. Furthermore, it is suggested that TOF adolescents show higher rates of psychiatric disorders. CONCLUSIONS: The neurodevelopment of TOF survivors is not intensively studied. Existing studies in TOF survivors focus on different developmental aspects, using different evaluation methods and thus making conclusions for either one of the four aspects of neurodevelopment (executive function, cognition, and adaptive function, speech-language and motor function, or neuropsychiatric domain). The poor outcomes of these isolated studies indicate the need for future research as well as for continuous neuropsychological assessment and close monitoring of children and adolescents with TOF.
Identification and Characterization of Polymorphisms in piRNA Regions
Authors: Lima José Roberto Sobrinho , Azevedo-Pinheiro Jhully , Andrade Roberta Borges , Khayat André Salim , Assumpção Paulo Pimentel de , Ribeiro-dos-Santos Ândrea , Batista dos Santos Sidney Emanuel , Moreira Fabiano Cordeiro
Published: February 2022

piRNAs are a class of noncoding RNAs that perform functions in epigenetic regulation and silencing of transposable elements, a mechanism conserved among most mammals. At present, there are more than 30,000 known piRNAs in humans, of which more than 80% are derived from intergenic regions, and approximately 20% are derived from the introns and exons of pre-mRNAs. It was observed that the expression of the piRNA profile is specific in several organs, suggesting that they play functional roles in different tissues. In addition, some studies suggest that changes in regions that encode piRNAs may have an impact on their function. To evaluate the conservation of these regions and explore the existence of a seed region, SNP and INDEL variant rates were investigated in several genomic regions and compared to piRNA region variant rates. Thus, data analysis, data collection, cleaning, treatment, and exploration were implemented using the R programming language with the help of the RStudio platform. We found that piRNA regions are highly conserved after considering INDELs and do not seem to present an identifiable seed region after considering SNPs and INDEL variants. These findings may contribute to future studies attempting to determine how polymorphisms in piRNA regions can impact diseases.
Diabetic Retinopathy: An Overview on Mechanisms, Pathophysiology and Pharmacotherapy
Authors: Ansari Prawej , Tabasumma Noushin , Snigdha Nayla Nuren , Siam Nawfal Hasan , Panduru Rachana V. N. R. S. , Azam Shofiul , Hannan J. M. A. , Abdel-Wahab Yasser H. A.
Published: February 2022

Diabetes mellitus is one of the most frequently occurring metabolic disorders (DMs), impairing healthy life around the globe, with mild-to-severe secondary complications. DM is associated with secondary complications, including diabetic retinopathy (DR), which damages the retina and can lead to vision loss. Diabetic patients often suffer from extreme retinal capillary aneurysms, hemorrhage, and edema, which is likely to lead to non-proliferative or proliferative diabetic retinopathy (NPDR or PDR) and diabetic macular edema (DME). Several epidemiological studies have illustrated that the occurrence of DR can vary by age of diabetes onset, diabetes type, and ethnicity. Although DR is very well-known, the complexity of its etiology and diagnosis makes therapeutic intervention difficult and challenging. We have reviewed different pathological aspects of diabetic retinopathy and its underlying mechanism of occurrence. In this review, we aim to provide an in-depth understanding and illustration of the progression of diabetic retinopathy, its pathophysiology, epidemiology, and prospective therapeutic targets.
DRONET: Multi-Tasking Framework for Real-Time Industrial Facility Aerial Surveillance and Safety
Authors: Ajakwe Simeon Okechukwu , Ihekoronye Vivian Ukamaka , Kim Dong-Seong , Lee Jae Min
Published: February 2022

The security of key and critical infrastructures is crucial for uninterrupted industrial process flow needed in strategic management as these facilities are major targets of invaders. The emergence of non-military use of drones especially for logistics comes with the challenge of redefining the anti-drone approach in determining a drone’s harmful status in the airspace based on certain metrics before countering it. In this work, a vision-based multi-tasking anti-drone framework is proposed to detect drones, identifies the airborne objects, determines its harmful status through perceived threat analysis, and checks its proximity in real-time prior to taking an action. The model is validated using manually generated 5460 drone samples from six (6) drone models under sunny, cloudy, and evening scenarios and 1709 airborne objects samples of seven (7) classes under different environments, scenarios (blur, scales, low illumination), and heights. The proposed model was compared with seven (7) other object detection models in terms of accuracy, sensitivity, F1-score, latency, throughput, reliability, and efficiency. The simulation result reveals that, overall, the proposed model achieved superior multi-drone detection accuracy of 99.6%, attached object identification of sensitivity of 99.80%, and F1-score of 99.69%, with minimal error, low latency, and less computational complexity needed for effective industrial facility aerial surveillance. A benchmark dataset is also provided for subsequent performance evaluation of other object detection models.
Application of IoT Quadrotor Dynamics Simulation
Authors: Lu Xinxi , Xing Zhihuan
Published: February 2022

With the development of consumer-grade drone products, drones have been good carriers for many IoT (Internet of Things) applications, especially as a part of edge computing to deliver things, collect data, or monitor objects. This paper develops a Unity3D-based quadrotor dynamics simulation component on the original platform. In order to complete the simulation, a force analysis is performed for the quadrotor to establish a physical model based on Newtonian mechanics and Euler angles, and a PID (Proportion Integral Differential)-based control model is developed based on this physical model, which performs a fixed-point control for the simulation. The component introduces weather impact factors into the physical model through an environmental computational model and presents weather effects to the user interface. In addition, we add a scene customization function and a multi-aircraft formation flight function to the original simulation, and optimize the interface presentation scheme for multi-aircraft formation flight. The quadrotor simulation model in this paper solves the problem that the original simulation system is not realistic enough and significantly improves the usability and stability of quadrotors working in the IoT area.
Ladislaus II Jagiełło (1386–1434)
Authors: Grzęda Mateusz
Published: February 2022

Ladislaus II Jagiełło (1386–1434). Ladislaus II Jagiełło is the founder of the Jagiellonian dynasty that had ruled over Poland and the Grand Duchy of Lithuania (until 1572), Bohemia (1471–1526) and Hungary (1440–1444, 1490–1526). A Grand Duke of Lithuania from 1377, and from 1386 a king of Poland and lord of Lithuania, which he ruled jointly with his cousin Witold (Vytautas), the son of Kęstutis. Five medieval portraits of Jagiełło survive, four of which date from the period of his reign in the Polish–Lithuanian state and one was executed posthumously. The earliest image, on Jagiełło’s Great Seal, was made in connection with his coronation as king of Poland (1386). Two portraits in the Holy Trinity Chapel at the Castle of Lublin (1418) are part of a wall paintings scheme commissioned by the monarch and executed by a team of painters brought from Ruthenia. Furthermore, the sumptuous tomb (before 1430) in Cracow was commissioned by the king. Its top slab bears an effigy of Jagiełło with his suggestively rendered countenance, which undoubtedly reflects the actual facial features of the elderly monarch. An image of the king represented as one of the Three Magi in a panel of an altarpiece in the tomb chapel of Casimir IV Jagiellonian, Jagiełło’s son and his successor on the Polish throne, dates from 1470. The chapel dedicated to the Holy Cross, erected at Cracow Cathedral, was in all likelihood commissioned by Casimir himself and his consort Elizabeth of Austria.
Fishery Status and Rebuilding of Major Economic Fishes in the Largest Freshwater Lake in China Based on Limited Data
Authors: Liu Yang , Fu Huiyun , Wang Linlong , Lin Li , He Gang , Fu Peifeng , Wang Changlai , Zhang Yanping , Kang Bin
Published: February 2022

Poyang Lake, the largest freshwater lake in China, possesses abundant fishery resources, but its fish stock status is still unclear. In this work, the stock status of and fishing efforts of nine major economic fishes in the Poyang Lake were estimated from 2000 to 2019 with a catch-based maximum sustainable yield (CMSY) model based on catch and resilience data. It was further predicted whether the biomass of those fishes could be restored to support maximum sustainable yield (Bmsy) under the policy of “Ten years fishing moratorium in the Yangtze River”. The results showed that goldfish Carassius auratus, grass carp Ctenopharyngodon idella, and black carp Mylopharyngodon piceus suffered from higher fishing efforts and low biomass in the past 20 years; bighead carp Hypophthalmichthys nobilis, yellow catfish Tachysurus fulvidraco, and common carp Cyprinus carpio responded differently to their fishing efforts; silver carp Hypophthalmichthys molitrix, Amur catfish Silurus asotus, and mandarin fish Siniperca chuatsi were underexploited. Six species were overfished in 2019, and their biomass would be expected to recover for sustainable exploitation during the fishing moratorium, except for M. piceus. This study provided a case study of feasible freshwater fishery evaluation in limnetic ecosystems.
Rim Breakups of Impacting Drops on a Superhydrophobic Surface and a Superheated Surface
Authors: Shirota Minori , Kato Masaki , Ishio Ai
Published: February 2022

The rim breakup of an impacting drop is experimentally investigated by comparing the impacts on superheated and superhydrophobic surfaces. The objective of the present study is to experimentally examine whether the Bo = 1 criteria holds for the rim breakups of drops impacting on the surfaces. A transparent sapphire plate was heated to achieve the Leidenfrost impact, which enables us to observe with a high-speed camera from below. The characteristics of the rim breakup were evaluated quantitatively using a particle tracking velocimetry method for both the rim and the drops generated. As a result, we clarified that Bo of the rim increases in the spreading phase and marks the highest value of 0.5 on a superheated surface, which is smaller than that on a pillar, where Bo ≈ 1. On a superhydrophobic surface, the highest Bo was 1.2, which is smaller than that on a wettable solid surface, 2.5, but close to the value on a pillar. We also revealed that diameters of generated drops collapse on a master curve when plotted as a function of pinch-off time for both the impacts on superheated and superhydrophobic surfaces.
Analysis of a Time-Fractional Substantial Diffusion Equation of Variable Order
Authors: Zheng Xiangcheng , Wang Hong , Guo Xu
Published: February 2022

A time-fractional substantial diffusion equation of variable order is investigated, in which the variable-order fractional substantial derivative accommodates the memory effects and the structure change of the surroundings of the physical processes with respect to time. The existence and uniqueness of the solutions to the proposed model are proved, based on which the weighted high-order regularity of the solutions, in which the weight function characterizes the singularity of the solutions, are analyzed.
Modelling of Electron and Thermal Transport in Quasi-Fractal Carbon Nitride Nanoribbons
Authors: Sibatov Renat T. , Golmankhaneh Alireza Khalili , Meftakhutdinov Ruslan M. , Morozova Ekaterina V. , Timkaeva Diana A.
Published: February 2022

In this work, using calculations based on the density functional theory, molecular dynamics, non-equilibrium Green functions method, and Monte Carlo simulation, we study electronic and phonon transport in a device based on quasi-fractal carbon nitride nanoribbons with Sierpinski triangle blocks. Modifications of electronic and thermal conductance with increase in generation g of quasi-fractal segments are estimated. Introducing energetic disorder, we study hopping electron transport in the quasi-fractal nanoribbons by Monte Carlo simulation of a biased random walk with generalized Miller–Abrahams transfer rates. Calculated time dependencies of the mean square displacement bear evidence of transient anomalous diffusion. Variations of anomalous drift-diffusion parameters with localization radius, temperature, electric field intensity, and energy disorder level are estimated. The hopping in quasi-fractal nanoribbons can serve as an explicit physical implementation of the generalized comb model.
Effect of Rotation Speed and Steel Microstructure on Joint Formation in Friction Stir Spot Welding of Al Alloy to DP Steel
Authors: Torkamani Hadi , Vivas Méndez Javier , Lecart Clement , Aldanondo Begiristain Egoitz , Alvarez Moro Pedro , Antti Marta-Lena
Published: February 2022

In this work, friction stir spot welding of 5754 aluminum alloy to dual phase steel was investigated using two different ratios of martensite and ferrite (0.38 and 0.61) for steel sheet initial microstructure and varying tool rotation speed (800, 1200 and 2000 rpm). The effect of these parameters on the joint formation was evaluated by studying the plunging force response during the process and the main characteristics of the joint at (i) macrolevel, i.e., hook morphology and bond width, and (ii) microlevel, i.e., steel hook and sheet microstructure and intermetallic compounds. The plunging force was reduced by increased tool rotation speed while there was no significant effect from the initial steel microstructure ratio of martensite and ferrite on the plunging force. The macrostructural characterization of the joints showed that the hook morphology and bond width were affected by the steel sheet initial microstructures as well as by the tool rotation speed and by the material flow driver; tool pin or shoulder. At microstructural level, a progressive variation in the ratio of martensite and ferrite was observed for the steel hook and sheet microstructure. The zones closer to the tool presented a fully martensitic microstructure while the zones away from the tool showed a gradual increase in the ferrite amount until reaching the ratio of ferrite and martensite of the steel sheet initial microstructure. Different types of FexAly intermetallic compounds were found in three zones of the joint; the hook tips, in the hooks close to the exit hole and in the corner of the exit hole. These compounds were characterized by a brittle behavior with hardness values varying from 456 to 937 HV01.
Curing Necrotic Angiodermatitis with an Intact Fish Skin Graft in a Patient Living with Diabetes
Authors: Dardari Dured , Lequint Corinne , Jugnet Anne Christine , Bénard Tatiana , Bouly Marie , Penfornis Alfred
Published: February 2022

Background and Objectives: We describe a case of necrotic angiodermatitis. Materials and Methods: We used an intact fish skin graft to treat a patient living with diabetes, which was complicated by end-stage renal failure and arterial hypertension. The entire therapeutic procedure was carried out in ambulatory care without requiring the hospitalization of the patient. Results: The patient experienced a marked reduction in pain and complete epithelization of the lesion after 10 weeks of treatment. Conclusion: Our experience presents a new therapeutic approach to necrotic angiodermatitis.
Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice
Authors: Hasan Nazmul , Sugimoto Koki , Yamada Koki , Morishige Jun-ichi , Ushijima Kentaro , Fujimura Akio , Nagata Naoto , Ando Hitoshi
Published: February 2022

Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a single dose of metformin has been reported to affect circadian clocks in the peripheral tissues. In this study, therefore, we investigated whether chronic treatment with metformin causes the impairment of circadian clocks, especially if given at an inappropriate time. Materials and Methods: Non-diabetic C57BL/6J mice were allowed access to food only during 4 h at the beginning of the dark period, and repeatedly i.p. injected with a nearly maximum non-toxic dose of metformin, once daily either at 4 h after the beginning of the dark period or at the beginning of the light period. Diabetic ob/ob mice were given free access to food and treated with metformin in drinking water. Results: Under the controlled feeding regimen, 8-day treatment with metformin did not alter the mRNA expression rhythms of clock genes in both liver and adipose tissue of C57BL/6J mice, regardless of dosing time. In addition, chronic treatment with metformin for 2 weeks affected hepatic AMPK activation rhythm but did not disrupt the circadian clocks in the liver and adipose tissues of the ob/ob mice. Conclusions: These results mitigate concerns that treatment with metformin impairs peripheral circadian clocks, although confirmation is needed in humans.
Pregnancy Complications Lead to Subclinical Maternal Heart Dysfunction—The Importance and Benefits of Follow-Up Using Speckle Tracking Echocardiography
Authors: Popescu Mihaela Roxana , Bouariu Alexandra , Ciobanu Anca Marina , Gică Nicolae , Panaitescu Anca Maria
Published: February 2022

Pregnancy complications such as gestational diabetes (GDM) and hypertensive disorders of pregnancy (HDP) are frequent and influence not only fetal outcomes but also the maternal cardiac function. GDM and HDP may act as a proxy for increased metabolic and cardiovascular risk later in life. Speckle tracking echocardiography (STE) is a relatively new imaging technique that provides more sensitive assessment than conventional echocardiography of the maternal cardiac function. Recent research suggests that STE can be used during pregnancy and postpartum as a useful method of early detection of subclinical maternal cardiac changes related to pregnancy complications, such as GDM and HDP, and as an indicator for future maternal cardiovascular disorders. The aim of this review was to underline the current value of STE in the follow-up protocol of high-risk pregnant women, as a mean for pre- and postpartum monitoring. A review of the literature was conducted in the PubMed database to select relevant articles regarding the association of STE changes and HDP or GDM in the prenatal and postpartum maternal evaluations. Both GDM and HDP are associated with subtle myocardial changes in shape, size and function; these preclinical cardiac changes, often missed by conventional evaluation, can be detected using STE. Left ventricular global circumferential strain might be an important predictor of maternal cardiovascular disorders and might help to define a high-risk group that requires regular monitoring later in life and timely intervention.
Identification of Carotenoids in Hairless Canary Seed and the Effect of Baking on Their Composition in Bread and Muffin Products
Authors: Abdel-Aal El-Sayed M. , Mats Lili , Rabalski Iwona
Published: February 2022

Carotenoids are essential components in the human diet due to their positive functions in ocular and cognitive health. This study investigated composition of carotenoids in hairless canary seed (HCS) as a novel food and the effect of baking on carotenoids in bread and muffin made from HCS, wheat and corn. Three bread formulations made from wheat and HCS blends were evaluated and compared with control wheat bread. In addition, three low-fat muffin recipes prepared from HCS alone or in blends with corn were assessed. The fate of carotenoid compounds in breads and muffins was monitored after dry mixing, dough/batter formation and oven baking. Carotenoids in products were quantified using UPLC and their identification was confirmed based on LC-MS/MS. Hairless canary seed and corn were fairly rich in carotenoids with a total content of 7.6 and 12.9 µg/g, respectively, compared with wheat (1.3 µg/g). Nineteen carotenoid compounds were identified, with all-trans lutein being the principal carotenoid in HCS followed by lutein 3-O-linoleate, lutein 3-O-oleate and lutein di-linoleate. There were significant reductions in carotenoids in muffin and bread products. It appears that batter or dough preparation causes more reductions in carotenoids than oven baking, probably due to enzymatic oxidation and degradation. Muffin-making resulted in lower lutein reductions compared with the bread-making process. The results suggest that muffins made from hairless canary seed alone or in blends with corn could boost the daily intake of lutein and/or zeaxanthin.
Tritordeum as an Innovative Alternative to Wheat: A Comparative Digestion Study on Bread
Authors: Nitride Chiara , D’Auria Giovanni , Dente Andrea , Landolfi Viola , Picariello Gianluca , Mamone Gianfranco , Blandino Massimo , Romano Raffaele , Ferranti Pasquale
Published: February 2022

Tritordeum results from the crossbreeding of a wild barley (Hordeum chilense) species with durum wheat (Triticum turgidum spp. turgidum). This hexaploid crop exhibits agronomic and rheological characteristics like soft wheat, resulting in an innovative raw material to produce baked goods. We applied a gel-based proteomic approach on refined flours to evaluate protein expression differences among two widespread tritordeum cultivars (Aucan and Bulel) taking as the reference semolina and flour derived from a durum and a soft wheat cvs, respectively. The products of in vitro digestion of model breads were analyzed to compare bio-accessibility of nutrients and mapping tritordeum bread resistant peptides. Significant differences among the protein profiles of the four flours were highlighted by electrophoresis. The amino acid bio-accessibility and the reducing sugars of tritordeum and wheat breads were comparable. Tritordeum cvs had about 15% higher alpha-amino nitrogen released at the end of the duodenal simulated digestion than soft wheat (p < 0.05). Bulel tritordeum flour, bread and digested bread had about 55% less R5-epitopes compared to the soft wheat. Differences in protein expression found between the two tritordeum cvs reflected in diverse digestion products and allergenic and celiacogenic potential of the duodenal peptides. Proteomic studies of a larger number of tritordeum cvs may be successful in selecting those with good agronomical performances and nutritional advantages.