bluuebunny/crossref_metadata_2025 huggingface dataset:
Perfect meta-absorber by using pod-like nanostructures with ultra-broadband, omnidirectional, and polarization-independent characteristics
Authors: Lin Yu-Sheng , Chen Wenjun
Published: May 2018

The on-chip perfect meta-absorber (PMA) is an important optical and thermal energy component in photovoltaics, thermal emitters, and energy harvesting applications. However, most reported PMAs rely on the complicated lithography techniques, which imposed a serious cost barrier on the development of practical applications, especially in the visible to near-infrared (NIR) wavelength range and at very large scales. Importantly, it is hard to realize PMA in the UV wavelength range by using current lithography techniques. In this article, we develop an ultra-broadband PMA by using natural lithography (NL) technique. The morphology of proposed PMA is randomly distributed pod-like nanostructures composed of a nanocomposite (Au/SiO2) covered a gold layer. It can be formed easily on Si substrate to function as an ultra-broadband, omnidirectional, and polarization-independent PMA by controlling the conditions of sputtering deposition and thermal annealing treatment. We experimentally realized an on-chip ultra-broadband PMA with almost 100% absorption spanned from UV-visible to NIR wavelength ranges. This cost-effective and high-efficiency approach would release the manufacturing barrier for previously reported PMAs and therefore open an avenue to the development of effectively energy harvesting, energy recycling, and heat liberation applications.
Maximum in density heterogeneities of active swimmers
Authors: Schwarzendahl Fabian Jan , Mazza Marco G.
Published: May 2018

A maximum in density heterogeneities of active swimmers results from the competition of hydrodynamics and steric interactions.
Compositional ripening of particle-stabilized drops in a three-liquid system
Authors: Otero Javier , Meeker Steven , Clegg Paul S.
Published: May 2018

A composition gradient between drops drives diffusion between them and the spontaneous formation of droplets which gel in the surrounding bath.
An enzymatic reaction mediated glucose sensor activated by MnO2 nanosheets acting as an oxidant and catalyst
Authors: Yan Guanwen , Zhang Yuan , Di Weihua
Published: May 2018

A self-regulated smart system would be highly desirable for analyte detection, in which a specific environment for detection could be self-modulated and the required reagents could also be in situ generated without further addition.
Determination of polycyclic aromatic hydrocarbons with molecular mass 302 in standard reference material 1597a by reversed-phase liquid chromatography and stop-flow fluorescence detection
Authors: Hayes Hugh V. , Wilson Walter B. , Sander Lane C. , Wise Stephen A. , Campiglia Andres D.
Published: May 2018

NPLC-RPLC/FL and stop-flow fluorescence spectral analysis for the six-ring MM 302 PAH isomers in SRM 1597a.
A new probe for detecting zinc-bound carbonic anhydrase in cell lysates and cells
Authors: Mehta Radhika , Qureshi Munaum H. , Purchal Meredith K. , Greer Sylvester M. , Gong Shanzhong , Ngo Chinh , Que Emily L.
Published: May 2018

A fluorescent probe for zinc-bound carbonic anhydrase is applied for tracking this protein in cell lysates and cells.
Improved radical stability of viologen anolytes in aqueous organic redox flow batteries
Authors: Hu Bo , Tang Yijie , Luo Jian , Grove Grant , Guo Yisong , Liu T. Leo
Published: May 2018

A 1.38 V aqueous organic redox flow battery demonstrated 97.48% capacity retention for 500 cycles and 128 mW cm−2 power density.
P–C reductive elimination in Ru(ii) complexes to convert triarylphosphine ligands into five- or six-membered phosphacycles
Authors: Kuwabara Takuya , Kato Takahiro , Takano Kouichi , Kodama Shintaro , Manabe Yuuka , Tsuchida Noriko , Takano Keiko , Minami Yasunori , Hiyama Tamejiro , Ishii Youichi
Published: May 2018

η4-Phosphacycle complexes were obtained from PPh2Ar (Ar = Ph, 1-Naph) via cyclometallation, alkyne insertion and P–C reductive elimination at a Ru centre.
Keggin-type polyoxometalate nanosheets: synthesis and characterizationviascanning transmission electron microscopy
Authors: Hiyoshi Norihito
Published: May 2018

Polyoxometalate nanosheets were synthesized and their structure was elucidated at the atomic and molecular levels.
Oxygen-induced high diffusion rate of magnesium dopants in GaN/AlGaN based UV LED heterostructures
Authors: Michałowski Paweł Piotr , Złotnik Sebastian , Sitek Jakub , Rosiński Krzysztof , Rudziński Mariusz
Published: May 2018

Oxygen breaks up Mg–H complexes and induces high diffusion of Mg in GaN/AlGaN heterostructures.
Imaging the ordering of a weakly adsorbed two-dimensional condensate: ambient-pressure microscopy and spectroscopy of CO2 molecules on rutile TiO2(110)
Authors: Hamlyn Rebecca C. E. , Mahapatra Mausumi , Grinter David C. , Xu Fang , Luo Si , Palomino Robert M. , Kattel Shyam , Waluyo Iradwikanari , Liu Ping , Stacchiola Dario J. , Senanayake Sanjaya D. , Rodriguez José A.
Published: May 2018

Disorder–order transitions found for CO2 on titania.
Recent advances in ruthenium-based olefin metathesis
Authors: Ogba O. M. , Warner N. C. , O’Leary D. J. , Grubbs R. H.
Published: May 2018

Ruthenium-based olefin metathesis catalysts, known for their functional group tolerance and broad applicability in organic synthesis and polymer science, continue to evolve as an enabling technology in these areas.
Aminotroponiminates: ligand-centred, reversible redox events under oxidative conditions in sodium and bismuth complexes
Authors: Hanft Anna , Lichtenberg Crispin
Published: May 2018

Redox-active bismuth complexes based on a new aminotroponiminate ligand with ferrocenyl substituents have been synthesised and characterised.
Copper(ii)-benzotriazole coordination compounds in click chemistry: a diagnostic reactivity study
Authors: Loukopoulos Edward , Abdul-Sada Alaa , Csire Gizella , Kállay Csilla , Brookfield Adam , Tizzard Graham J. , Coles Simon J. , Lykakis Ioannis N. , Kostakis George E.
Published: May 2018

This diagnostic study aims to shed light on the catalytic activity of a library of Cu(ii) based coordination compounds with benzotriazole-based ligands.
Programmable arrangement of metal ions in a cofacially stacked assembly of porphyrinoids toward molecular tags
Authors: Mihara Nozomi , Yamada Yasuyuki , Furukawa Ko , Kato Tatsuhisa , Tanaka Kentaro
Published: May 2018

Cofacial assemblies of metalloporphyrinoides represent a fascinating platform for the novel functional metal arrays to be molecular tags.
Comparative efficacy of vanilloids in inhibiting toll-like receptor-4 (TLR-4)/myeloid differentiation factor (MD-2) homodimerisation
Authors: Mai Chun-Wai , Kang Yew Beng , Hamzah Ahmad Sazali , Pichika Mallikarjuna Rao
Published: May 2018

Vanilloids in commonly eaten foods are anti-inflammatoryviainhibition of TLR-4/MD-2 homodimerisation. 6-Shogaol is the most potent vanilloid.
Catalytic depolymerisation of suberin rich biomass with precious metal catalysts
Authors: McCallum Christopher S. , Strachan Nicholas , Bennett Stephen C. , Forsythe W. Graham , Garrett Mark D. , Hardacre Christopher , Morgan Kevin , Sheldrake Gary N.
Published: May 2018

Hydrogenolysis of cork has been examined using a range of precious metal catalysts studying the effect of the support, added base and solvent used.
Au–Fe nanoparticles visited by MD simulation: structural and thermodynamic properties affected by chemical composition
Authors: Akbarzadeh Hamed , Mehrjouei Esmat , Shamkhali Amir Nasser , Abbaspour Mohsen , Salemi Sirous , Kamrani Maliheh
Published: May 2018

In this work, Fe–Au nanoalloys and Fe@Au core–shell nanoclusters are investigated via classical molecular dynamics simulation to determine the effect of their composition on their thermodynamic stability and melting mechanism.
Biological perspectives of a FRET based pH-probe exhibiting molecular logic gate operation with altering pH
Authors: Srivastava Priyanka , Srivastava Payal , Patra Ashis K.
Published: May 2018

A FRET probe for applications in pH sensing, CT-DNA/BSA interactions and logic gate/circuit construction with H+/OH−ions.
Correction: Synthesis and structural characterization of metal complexes with macrocyclic tetracarbene ligands
Authors: Fei Fan , Lu Taotao , Chen Xue-Tai , Xue Zi-Ling
Published: May 2018

Correction for ‘Synthesis and structural characterization of metal complexes with macrocyclic tetracarbene ligands’ by Fan Fei et al., New J. Chem., 2017, 41, 13442–13453.
Selectively arranged single-wire based nanosensor array systems for gas monitoring
Authors: Chmela O. , Sadílek J. , Domènech-Gil G. , Samà J. , Somer J. , Mohan R. , Romano-Rodriguez A. , Hubálek J. , Vallejos S.
Published: May 2018

Arrays of gas nanosensors comprised of electrodes with finger-widths of ∼100 nm and nanowires (<100 nm) are fabricated and validated.
Proteins as supramolecular hosts for C60: a true solution of C60 in water
Authors: Di Giosia Matteo , Bomans Paul H. H. , Bottoni Andrea , Cantelli Andrea , Falini Giuseppe , Franchi Paola , Guarracino Giuseppe , Friedrich Heiner , Lucarini Marco , Paolucci Francesco , Rapino Stefania , Sommerdijk Nico A. J. M. , Soldà Alice , Valle Francesco , Zerbetto Francesco , Calvaresi Matteo
Published: May 2018

Lysozyme is used as a host molecule to disperse monomolecularly C60 in water preserving the C60 properties.
Manipulation of a DNA aptamer–protein binding site through arylation of internal guanine residues
Authors: Van Riesen Abigail J. , Fadock Kaila L. , Deore Prashant S. , Desoky Ahmed , Manderville Richard A. , Sowlati-Hashjin Shahin , Wetmore Stacey D.
Published: May 2018

Chemically modified aptamers have the opportunity to increase aptamer target binding affinity and provide structure–activity relationships to enhance our understanding of molecular target recognition by the aptamer fold.
Correction: Photothermal Möbius aromatic metallapentalenofuran and its NIR-responsive copolymer
Authors: Lu Zhengyu , Cai Yuanting , Wei Yuanqing , Lin Qin , Chen Jiangxi , He Xumin , Li Shunhua , Wu Weitai , Xia Haiping
Published: May 2018

Correction for ‘Photothermal Möbius aromatic metallapentalenofuran and its NIR-responsive copolymer’ by Zhengyu Lu et al., Polym. Chem., 2018, 9, 2092–2100.
Selective formation of phthalimides from amines, aldehydes and CO by Pd-catalyzed oxidative C–H aminocarbonylation
Authors: Shi Renyi , Liao Fan , Niu Huiying , Lei Aiwen
Published: May 2018

The Pd/Cu-catalyzed intramolecular C–H bond aminocarbonylation utilizing imines as the amine source has been developed. This transformation provides an efficient and straightforward protocol for the synthesis of phthalimides which widely exist in natural products, pharmaceutical and functional materials. Various functional groups are tolerated and the yields are up to 99%.
Synthesis of bay-triaminosubstituted perylenediimides
Authors: Gutiérrez-Moreno D. , Sastre-Santos Á. , Fernández-Lázaro F.
Published: May 2018

A mild fluoride-mediated reaction for the synthesis of 1,6,7-triaminoperylenediimides.
Sorption of tetracycline on biochar derived from rice straw and swine manure
Authors: Wang Hua , Fang Chengran , Wang Qun , Chu Yixuan , Song Yali , Chen Yongmin , Xue Xiangdong
Published: May 2018

Comparing the adsorption ability of biochar from swine manure and rice straw on tetracycline and investigating the relative mechanisms involved in the process.
Molybdenum(0) tricarbonyl and tetracarbonyl complexes with a cationic pyrazolylpyridine ligand: synthesis, crystal structures and catalytic performance in olefin epoxidation
Authors: Nogueira Lucie S. , Neves Patrícia , Gomes Ana C. , Lavrador Pedro , Cunha-Silva Luís , Valente Anabela A. , Gonçalves Isabel S. , Pillinger Martyn
Published: May 2018

The oxidative decarbonylation and catalytic chemistry of molybdenum(0) tricarbonyl and tetracarbonyl complexes containing the same diimine ligand are compared.
Crystal-seeds induced construction of ZnO–ZnFe2O4 micro-cubic composites as excellent anode materials for lithium ion battery
Authors: Pan Pei , Wang Ting , Chen Lihui , Wang Feng , Yang Xiong , Qin Caiqin , Ding Yu
Published: May 2018

This work aims at designing a fine assembly of two different transition metal oxides with a distinct band-gap energy into a bi-component-active hetero-structure to improve electrochemical performance.
Interspecies comparison in the COMT-mediated methylation of 3-BTD
Authors: Xia Yangliu , Pang Huilin , Dou Tongyi , Wang Ping , Ge Guangbo
Published: May 2018

The methylation behaviour of 3-BTD in liver S9 from eight different species was characterized with respect to the similarities and differences of their metabolic profiles, catalytic efficacy and inhibitory potency by a known chemical inhibitor.
Characterization of three-point bending properties of metal–resin interpenetrating phase composites
Authors: Yao Bibo , Zhou Zhaoyao , Duan Liuyang , Chen Zengtao
Published: May 2018

Three-point bending properties of the metal–resin IPCs exhibit anisotropy. Flexural strength increases with increasing fiber fractions and finer fibers improve the properties. The fracture shows both brittle and plastic characteristics.
The formation and growth of calcium sulfate crystals through oxidation of SO2by O3on size-resolved calcium carbonate
Authors: Zhang Ying , Tong Shengrui , Ge Maofa , Jing Bo , Hou Siqi , Tan Fang , Chen Yi , Guo Yucong , Wu Lingyan
Published: May 2018

The heterogeneous formation pathway of rod-like calcium sulfate crystals in the atmosphere.
Influences of novel microwave drying on dissolution of new formulated naproxen sodium
Authors: Al-Ali Maha , Selvakannan P. R. , Parthasarathy Rajarathinam
Published: May 2018

Novel microwave mediated drying of naproxen sodium has been shown as an efficient drying technique as well as exhibiting a critical role in improving the dissolution kinetics.
Structural effects on the catalytic activity of carbon-supported magnetite nanocomposites in heterogeneous Fenton-like reactions
Authors: Zang Hongmei , Miao Chunyan , Shang Jianying , Liu Yingxin , Liu Juan
Published: May 2018

This study revealed that the geometrical structure of a carbonaceous support can significantly impact the catalytic activity of the whole nanocomposites.
Use of novel haptens in the production of antibodies for the detection of tryptamines
Authors: Maryška Michal , Fojtíková Lucie , Jurok Radek , Holubová Barbora , Lapčík Oldřich , Kuchař Martin
Published: May 2018

We synthesized haptens derived from tryptamine-based drugs and used them in the production of antibodies against various tryptamines.
Assessment of EtQxBox complexation in solution by steady-state and time-resolved fluorescence spectroscopy
Authors: Aprile Arianna , Palermo Giovanna , De Luca Antonio , Pinalli Roberta , Dalcanale Enrico , Pagliusi Pasquale
Published: May 2018

We investigate the role of combined static and dynamic quenching in fluorescence transduction of benzonitrile and acetonitrile complexation by a rigid quinoxaline-based cavitand.
Correction: Sustained delivery of anti-VEGF from injectable hydrogel systems provides a prolonged decrease of endothelial cell proliferation and angiogenesis in vitro
Authors: Fletcher Nathan A. , Krebs Melissa D.
Published: May 2018

Correction for ‘Sustained delivery of anti-VEGF from injectable hydrogel systems provides a prolonged decrease of endothelial cell proliferation and angiogenesis in vitro’ by Nathan A. Fletcher et al., RSC Adv., 2018, 8, 8999–9005.
From jamming to collective cell migration through a boundary induced transition
Authors: Chepizhko Oleksandr , Lionetti Maria Chiara , Malinverno Chiara , Giampietro Costanza , Scita Giorgio , Zapperi Stefano , La Porta Caterina A. M.
Published: May 2018

By combining simulations and experiments, Chepizhko et al. show that jammed cellular layers rapidly revert into a flowing state after a wound.
Facile fabrication of thermo/redox responsive hydrogels based on a dual crosslinked matrix for a smart on–off switch
Authors: Sun Na , Sun Panpan , Wu Aoli , Qiao Xuanxuan , Lu Fei , Zheng Liqiang
Published: May 2018

A thermo- and redox-responsive polyelectrolyte hydrogel was facilely constructed based on a primary chemical crosslinking and a secondary physical crosslinking.
Separately enhanced dual emissions of the amphiphilic derivative of 2-(2′-hydroxylphenyl) benzothiazole by supramolecular complexation
Authors: Wu Chengfeng , Jin Yingzhi , Li Dahua , Ding Lan , Xing Yuzhi , Zhang Kaicheng , Song Bo
Published: May 2018

Separately enhanced dual emissions of the amphiphilic derivative of 2-(2′-hydroxyphenyl)benzothiazole were realized by supramolecular complexations with α-CD and β-CD.
Metal–organic framework-derived Zn0.975Co0.025S/CoS2 embedded in N,S-codoped carbon nanotube/nanopolyhedra as an efficient electrocatalyst for overall water splitting
Authors: Yu Zhou , Bai Yu , Zhang Shimin , Liu Yuxuan , Zhang Naiqing , Sun Kening
Published: May 2018

Zn0.975Co0.025S/CoS2 embedded in N,S-codoped carbon nanotube/nanopolyhedra can be prepared from MOFs and shows excellent catalytic performance for water splitting.
Synthesis of MoS2 from [Mo3S7(S2CNEt2)3]I for enhancing photoelectrochemical performance and stability of Cu2O photocathode toward efficient solar water splitting
Authors: Shinde P. S. , Fontenot P. R. , Donahue J. P. , Waters J. L. , Kung P. , McNamara L. E. , Hammer N. I. , Gupta A. , Pan S.
Published: May 2018

A facile synthesis protocol is highlighted for catalytic MoS2, whose conformal thin film modification on Cu2O photocathode greatly enhances its photocurrent, reduces photo-corrosion and improves photostability.
Alkaline earth metal oxide nanocluster modification of rutile TiO2 (110) promotes water activation and CO2 chemisorption
Authors: Nolan Michael
Published: May 2018

Rutile TiO2 modified with alkaline earth oxide nanoclusters promotes water activation and capture of CO2.
Carbon quantum dot sensitized integrated Fe2O3@g-C3N4core–shell nanoarray photoanode towards highly efficient water oxidation
Authors: Yi Sha-Sha , Yan Jun-Min , Jiang Qing
Published: May 2018

The carbon quantum dot (CQD) sensitized integrated Ti:Fe2O3@g-C3N4core–shell nanoarrays demonstrate superior PEC water oxidation performance which can be ascribed to efficient charge separation efficiency derived from the well-confined heterojunction structure together with the high catalytic activity of the CQDs for H2O2decomposition.
Correction: Co-mixing hydrogen and methane may double the energy storage capacity
Authors: Xue Qianqian , Wu Menghao , Zeng Xiao Cheng , Jena Puru
Published: May 2018

Correction for ‘Co-mixing hydrogen and methane may double the energy storage capacity’ by Qianqian Xue et al., J. Mater. Chem. A, 2018, DOI: 10.1039/c8ta01909f.
Exploring the role of spin-triplets and trap states in photovoltaic processes of perovskite solar cells
Authors: Lu Kai , Zhao Chen , Luan Lin , Duan Jiashun , Xie Yulin , Shao Ming , Hu Bin
Published: May 2018

Revealing the role of spin-triplets and trap states in the recombination and dissociation processes in PSCs.
Controlling the charge transfer flow at the graphene/pyrene–nitrilotriacetic acid interface
Authors: Osella Silvio , Kiliszek Małgorzata , Harputlu Ersan , Unlu Cumhur G. , Ocakoglu Kasim , Kargul Joanna , Trzaskowski Bartosz
Published: May 2018

Tuning of the charge flow direction at the SAM–graphene interface by coordination of the SAM with a nickel cation.
Simultaneous enhancement of charge density and molecular stacking order of polymer semiconductors by viologen dopants for high performance organic field-effect transistors
Authors: Lee Dong-Hyeon , Kang Minji , Lim Dae-Hee , Kim Yunseul , Lee Jiyoul , Kim Dong-Yu , Baeg Kang-Jun
Published: May 2018

Simultaneous enhancement of both charge density and favourable molecular stacking order by the incorporation of a molecular dopant in π-conjugated polymer.
Efficient red AIEgens based on tetraphenylethene: synthesis, structure, photoluminescence and electroluminescence
Authors: Li Yinghao , Wang Weigao , Zhuang Zeyan , Wang Zhiming , Lin Gengwei , Shen Pingchuan , Chen Shuming , Zhao Zujin , Tang Ben Zhong
Published: May 2018

Efficient nondoped red OLEDs are achieved based on new red AIEgens.
Big-data and machine learning to revamp computational toxicology and its use in risk assessment
Authors: Luechtefeld Thomas , Rowlands Craig , Hartung Thomas
Published: May 2018

The creation of large toxicological databases and advances in machine-learning techniques have empowered computational approaches in toxicology. Work with these large databases based on regulatory data has allowed reproducibility assessment of animal models, which highlight weaknesses in traditional in vivo methods. This should lower the bars for the introduction of new approaches and represents a benchmark that is achievable for any alternative method validated against these methods. Quantitative Structure Activity Relationships (QSAR) models for skin sensitization, eye irritation, and other human health hazards based on these big databases, however, also have made apparent some of the challenges facing computational modeling, including validation challenges, model interpretation issues, and model selection issues. A first implementation of machine learning-based predictions termed REACHacross achieved unprecedented sensitivities of >80% with specificities >70% in predicting the six most common acute and topical hazards covering about two thirds of the chemical universe. While this is awaiting formal validation, it demonstrates the new quality introduced by big data and modern data-mining technologies. The rapid increase in the diversity and number of computational models, as well as the data they are based on, create challenges and opportunities for the use of computational methods.
A phosphatidic acid-binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa
Authors: Groenewold Maike K. , Massmig Marco , Hebecker Stefanie , Danne Linna , Magnowska Zofia , Nimtz Manfred , Narberhaus Franz , Jahn Dieter , Heinz Dirk W. , Jänsch Lothar , Moser Jürgen
Published: May 2018

A quantitative Pseudomonas aeruginosa proteomics approach revealed increased abundance of the so-far uncharacterized protein PA3911 in anaerobic biofilms grown under conditions of the cystic fibrosis lung. Physiological relevance of ORF PA3911 was demonstrated, inter alia, using phenotype microarray experiments. The mutant strain showed increased susceptibility in the presence of antimicrobials (minocycline, nafcillin, oxacillin, chloramphenicol and thiamphenicol), enhanced twitching motility and significantly impaired biofilm formation. PA3911 is a soluble, cytoplasmic protein in P. aeruginosa. In protein–lipid overlay experiments, purified PA3911 bound specifically to phosphatidic acid (PA), the central hub of phospholipid metabolism. Structure-guided site-directed mutagenesis was used to explore the proposed ligand-binding cavity of PA3911. Protein variants of Leu56, Leu58, Val69 and Leu114 were shown to impair PA interaction. A comparative shotgun lipidomics approach demonstrated a multifaceted response of P. aeruginosa to anaerobic conditions at the lipid head group and fatty acid level. Lipid homeostasis in the PA3911 mutant strain was imbalanced with respect to lysophosphatidylcholine, phosphatidylcholine and diacylglycerol under anaerobic and/or aerobic conditions. The impact of the newly identified PA-binding protein on lipid homeostasis and the related macroscopic phenotypes of P. aeruginosa are discussed.
Long non-coding RNA AK096174 promotes cell proliferation and invasion in gastric cancer by regulating WDR66 expression
Authors: Zhang Yeqian , Yu Site , Zhang Zizhen , Zhao Gang , Xu Jia
Published: May 2018

Gastric cancer (GC) is one of the major causes of cancer deaths worldwide; however, the mechanism of carcinogenesis is complex and poorly understood. Long non-coding RNA (lncRNA) has been reported to be involved in the development of multiple cancers. Here, we identified a novel lncRNA, AK096174, which was up-regulated and associated with tumorigenesis, tumor size, metastasis, and poor prognosis in GC. Our data showed that AK096174 was highly expressed in the GC tissues and cell lines (SGC-7901, AGS, BGC-823, MGC-803), and patients with higher AK096174 expression had a poorer prognosis and shorter overall survival (OS). AK096174 knockdown inhibited the proliferation, migration, and invasiveness in SGC-7901 and BGC-823 cells, whereas AK096174 overexpression had the promoting effects. Furthermore, mechanistic investigation showed that AK096174 positively correlated with the expression of WD repeat-containing protein 66 (WDR66) gene at the translational level. Knockdown of WRD66 attenuated the positive impact of AK096174 in GC cells. The findings of the present study establish a function for AK096174 in GC progression and suggest it may serve as a potential target for GC therapy in the future.
Lack of association between miR-218 rs11134527 A>G and Kawasaki disease susceptibility
Authors: Pi Lei , Fu Lanyan , Xu Yufen , Che Di , Deng Qiulian , Huang Xijing , Li Meiai , Zhang Li , Huang Ping , Gu Xiaoqiong
Published: May 2018

Kawasaki disease (KD) is a type of disease that includes the development of a fever that lasts at least 5 days and involves the clinical manifestation of multicellular vasculitis. KD has become one of the most common pediatric cardiovascular diseases. Previous studies have reported that miR-218 rs11134527 A>G is associated with susceptibility to various cancer risks. However, there is a lack of evidence regarding the relationship between this polymorphism and KD risk. The present study explored the correlation between the miR-218 rs11134527 A>G polymorphism and the risk of KD. We recruited 532 patients with KD and 623 controls to genotype the miR-218 rs11134527 A>G polymorphism with a TaqMan allelic discrimination assay. Our results illustrated that the miR-218 rs11134527 A>G polymorphism was not associated with KD risk. In an analysis stratified by age, sex, and coronary artery lesions, we found only that the risk of KD was significantly decreased for children older than 5 years (GG vs. AA/AG: adjusted OR = 0.26, 95% CI = 0.07–0.94, P=0.041). The present study demonstrated that the miR-218 rs1113452 A>G polymorphism may have an age-related relationship with KD susceptibility that has not previously been revealed.
To be or not to be... secreted as exosomes, a balance finely tuned by the mechanisms of biogenesis
Authors: Palmulli Roberta , van Niel Guillaume
Published: May 2018

The release of extracellular vesicles such as exosomes provides an attractive intercellular communication pathway. Exosomes are 30- to 150-nm membrane vesicles that are generated in endosomal compartment and act as intercellular mediators in both physiological and pathological context. Despite the growing interest in exosome functions, the mechanisms responsible for their biogenesis and secretion are still not completely understood. Knowledge about these mechanisms is important because they control the composition, and hence the function and secretion, of exosomes. Exosomes are produced as intraluminal vesicles in extremely dynamic endosomal organelles, which undergo various maturation processes in order to form multivesicular endosomes. Notably, the function of multivesicular endosomes is balanced between exosome secretion and lysosomal degradation. In the present review, we present and discuss each intracellular trafficking pathway that has been reported or proposed as regulating exosome biogenesis, with a particular focus on the importance of endosomal dynamics in sorting out cargo proteins to exosomes and to the secretion of multivesicular endosomes. An overall picture reveals several key mechanisms, which mainly act at the crossroads of endosomal pathways as regulatory checkpoints of exosome biogenesis.
Cell–cell communication via ciliary extracellular vesicles: clues from model systems
Authors: Wang Juan , Barr Maureen M.
Published: May 2018

In this short review, we will focus on the uniqueness of ciliary extracellular vesicles (EVs). In particular, we will review what has been learned regarding EVs produced by cilia of model organisms. Model systems including Chlamydomonas, Caenorhabditis elegans, and mouse revealed the fundamental biology of cilia and flagella and provide a paradigm to understand the roles of cilia and flagella in human development, health, and disease. Likewise, we propose that general principles learned from model systems regarding ciliary EV biogenesis and functions may provide a framework to explore the roles of ciliary EVs in human development, health, and disease.
Probabilistic–possibilistic model for a parking lot in the smart distribution network expansion planning
Authors: Nasri Amirhossein , Abdollahi Amir , Rashidinejad Masoud , Hadi Amini M.
Published: May 2018

Conventional distribution network departs to the smart grid. The parking lot will have an important role in the smart grid as a distributed generation. Due to the output power of parking lots is uncertain, More accurate modeling of parking lot output power is necessary for the future of distribution network studies such as Distribution Network Expansion Planning (DNEP). In this paper, a systematic method based on the Z ‐number concept is utilized to represent the uncertainty of Vehicle to Grid's (V2G's) presence. In order to investigate the impact of V2Gs uncertainty on the DNEP, we proposed a Probabilistic–Possibilistic DNEP in the presence of V2Gs referred to as P‐PDNEPV2G. If the V2Gs historical data is incomplete, the proposed structure can significantly consider the effects of V2G on the DNEP. In P‐PDNEPV2G, parking lots output power is described as a probabilistic–possibilistic variable by Z ‐number method. The optimization of P‐PDNEPV2G is executed by the Non‐Dominated Sorting Genetic Algorithm (NSGA‐II). A 24‐bus test system and the real 20 kV distribution network of Ghale‐Ganj city of Kerman province in Iran are used to demonstrate the effectiveness of the proposed methodology. Eventually, several analyses are conducted to investigate the impact of probabilistic–possibilistic V2G model on the DNEP problem.
Image splicing detection based on Markov features in discrete octonion cosine transform domain
Authors: Sheng Hongda , Shen Xuanjing , Lyu Yingda , Shi Zenan , Ma Shuyang
Published: May 2018

To improve the poor robustness and low accuracy of the existing algorithms of image splicing detection, a novel passive image forgery detection method is proposed in this study, which is based on DOCT (discrete octonion cosine transform) and Markov. By introducing the octonion and DOCT, the colour information of six image channels (the RGB model and the HSI model) can be exhaustively extracted, which enhances the robustness of the algorithm. On the issue of improving the detection accuracy, the standard deviation is used to characterise the relationship of the colour information between the parts of DOCT coefficient matrix, and the K‐fold cross‐validation is introduced to improve the identification performance of the classifier. The steps of the algorithm are as follows: Firstly, the 8 × 8 block DOCT transform is used to the original image to obtain parts of block DOCT coefficient. Secondly, the standard deviation is used to process the corresponding parts of all blocks of the image. Finally, the Markov feature vector of the DOCT coefficient is extracted and feds to the LIBSVM (a library for support vector machines). When using LIBSVM for classification, K‐fold cross‐validation is executed to select the best parameter pairs. The experiment results demonstrate that the algorithm is superior to the other state‐of‐the‐art splicing detection methods.
Using duobinary with first‐ and second‐order optical equalisers for extending transmission distance of optical access networks
Authors: Dong‐Nhat Nguyen , Nguyen Lim , Malekmohammadi Amin
Published: May 2018

This study presents the external modulation and direct detection of duobinary signal in optical access networks at 25 and 50 Gb/s with the use of first‐order optical equaliser at the transmitter output (pre‐equalisation) to compensate the waveform distortion induced by fibre dispersion. The first‐order optical equaliser is then replaced by second‐order optical equaliser to further improve the bit error rate (BER) performance and extend the maximum transmission distance by compensating the residual dispersion for the first time. The authors explain the enhancement in the BER by analysing the eye diagrams and optical spectra. The authors also investigate non‐return‐to‐zero signal with similar setup parameters for reference.
Blood glucose regulation in type 1 diabetic patients: an adaptive parametric compensation control‐based approach
Authors: Nath Anirudh , Deb Dipankar , Dey Rajeeb , Das Sipon
Published: May 2018

Here, a direct adaptive control strategy with parametric compensation is adopted for an uncertain non‐linear model representing blood glucose regulation in type 1 diabetes mellitus patients. The uncertain parameters of the model are updated by appropriate design of adaptation laws using the Lyapunov method. The closed‐loop response of the plasma glucose concentration as well as external insulin infusion rate is analysed for a wide range of variation of the model parameters through extensive simulation studies. The result indicates that the proposed adaptive control scheme avoids severe hypoglycaemia and gives satisfactory performance under parametric uncertainty highlighting its ability to address the issue of inter‐patient variability.
Examination of the impingement of interface trap charges on heterogeneous gate dielectric dual material control gate tunnel field effect transistor for the refinement of device reliability
Authors: Gupta Sarthak , Sharma Dheeraj , Soni Deepak , Yadav Shivendra , Aslam Mohd. , Yadav Dharmendra Singh , Nigam Kaushal , Sharma Neeraj
Published: May 2018

In this work, the authors have reported the reliability issues of dual material control gate tunnel field effect transistor (DMCG‐TFET) and proposed heterogeneous gate dielectric dual metal control gate tunnel field effect transistors (HD DMCG‐TFETs) in terms of interface trap charges (ITCs). The positive and negative types of localised charges at the semiconductor/insulator interface cause degradation in the device performance (DC/RF). In this regard, the proposed structure which includes combination of low‐K and high‐K dielectric improves the immunity towards the ITCs at the interface of semiconductor/insulator with better performance. In this concern, the study has analysed the impact of ITCs on DC and analogue/RF performances of the DMCG‐TFET and HD DMCG‐TFET in terms of various parameters like electric field, energy band diagram, carrier concentration, transfer characteristics, transconductance (), cutoff frequency () and gain bandwidth product. Further to this, impact on device linearity parameters is also analysed through higher order of transconductance coefficients (), VIP2, VIP3 and IIP3.
Experimental investigation on the viscosity of hybrid nanofluids made of two kinds of nanoparticles mixed in engine oil
Authors: Liu Yan , Yin Deshun , Tian Mingyuan , Hu Xichen , Chen Xuan
Published: May 2018

To investigate the viscosity of hybrid nanofluids containing two kinds of nanoparticles, a series of experiments are conducted on TiO2–Ag/engine oil, Al2O3–Ag/engine oil (a mixture of the volume ratio of 50:50) nanofluids under different shear rates and volume fractions. The results show that the viscosity decreases with increasing shear rate, which suggests TiO2–Ag/engine oil and Al2O3–Ag/engine oil hybrid nanofluids are both shear thinning fluids, whilst the viscosity of all samples enhances with the increase of volume fraction. Moreover, an interesting result is observed that the hybrid nanofluids have a lower viscosity than single particle nanofluids. Also, through the validating experiment based on Al2O3–Al2O3/engine oil with different diameters, it shows that different materials with unlike morphologies mixture are more likely to reduce the viscosity than dissimilar nanoparticles mixture of just one material.
Leaves on trees: identifying halo stars with extreme gradient boosted trees
Authors: Veljanoski Jovan , Helmi Amina , Breddels Maarten , Posti Lorenzo
Published: May 2018

Context. Extended stellar haloes are a natural by-product of the hierarchical formation of massive galaxies like the Milky Way. If merging is a non-negligible factor in the growth of our Galaxy, evidence of such events should be encoded in its stellar halo. The reliable identification of genuine halo stars is a challenging task, however.

Aims. With the advent of the Gaia space telescope, we are ushered into a new era of Galactic astronomy. The first Gaia data release contains the positions, parallaxes, and proper motions for over two million stars, mostly in the solar neighbourhood. The second Gaia data release will enlarge this sample to over 1.5 billion stars, the brightest ~ 5 million of which will have full phase-space information. Our aim for this paper is to develop a machine learning model for reliably identifying halo stars, even when their full phase-space information is not available.

Methods. We use the Gradient Boosted Trees algorithm to build a supervised halo star classifier. The classifier is trained on a sample of stars extracted from the Gaia Universe Model Snapshot, which is also convolved with the errors of the public TGAS data, which is a subset of Gaia DR1, as well as with the expected uncertainties for the upcoming Gaia DR2 catalogue. We also trained our classifier on a dataset resulting from the cross-match between the TGAS and RAVE catalogues, where the halo stars are labelled in an entirely model-independent way. We then use this model to identify halo stars in TGAS.

Results. When full phase-space information is available and for Gaia DR2-like uncertainties, our classifier is able to recover 90% of the halo stars with at most 30% distance errors, in a completely unseen test set and with negligible levels of contamination. When line-of-sight velocity is not available, we recover ~ 60% of such halo stars, with less than 10% contamination. When applied to the TGAS catalogue, our classifier detects 337 high confidence red giant branch halo stars. At first glance this number may seem small, however, it is consistent with the expectation from the models, given the uncertainties in the data. The large parallax errors are in fact the biggest limitation in our ability to identify a large number of halo stars in all the cases studied.
Dust modelling and a dynamical study of comet 41P/Tuttle–Giacobini–Kresak during its 2017 perihelion passage
Authors: Pozuelos F. J. , Jehin E. , Moulane Y. , Opitom C. , Manfroid J. , Benkhaldoun Z. , Gillon M.
Published: May 2018

Context. Thanks to the Rosetta mission, our understanding of comets has greatly improved. A very good opportunity to apply this knowledge appeared in early 2017 with the appearance of the Jupiter family comet 41P/Tuttle–Giacobini–Kresak. The comet was only 0.15 au from the Earth as it passed through perihelion on April 12, 2017. We performed an observational campaign with the TRAPPIST telescopes that covered almost the entire period of time when the comet was active.

Aims. In this work we present a comprehensive study of the evolution of the dust environment of 41P based on observational data from January to July, 2017. In addition, we performed numerical simulations to constrain its origin and dynamical nature.

Methods. To model the observational data set we used a Monte Carlo dust tail model, which allowed us to derive the dust parameters that best describe its dust environment as a function of heliocentric distance: its dust production rate, the size distribution and ejection velocities of the dust particles, and its emission pattern. In order to study its dynamical evolution, we completed several experiments to evaluate the degree of stability of its orbit, its life time in its current region close to Earth, and its future behaviour.

Results. From the dust analysis, we found that comet 41P is a dust-poor comet compared to other comets of the same family, with a complex emission pattern that shifted from full isotropic to anisotropic ejection sometime during February 24–March 14 in 2017, and then from anisotropic to full isotropic again between June 7 and 28. During the anisotropic period, the emission was controlled by two strongly active areas, where one was located in the southern and one in the northern hemisphere of the nucleus. The total dust mass loss is estimated to be ~7.5 × 108kg. From the dynamical simulations we estimate that ~3600 yr is the period of time during which 41P will remain in a similar orbit. Taking into account the estimated mass loss per orbit, after 3600 yr, the nucleus may lose about 30% of its mass. However, based on its observed dust-to-water mass ratio and its propensity to outbursts, the lifetime of this comet could be much shorter.
Introduced alien signal crayfish (Pacifastacus leniusculus) in Finland − uncontrollable expansion despite numerous crayfisheries strategies
Authors: Ruokonen Timo J. , Sjövik Rosanna , Erkamo Esa , Tulonen Jouni , Ercoli Fabio , Kokko Harri , Jussila Japo
Published: May 2018

In Finland, massive signal crayfish introductions started towards the end of 1980s, with an estimated total of 2.2 million signal crayfish been stocked before year 2016. During that period, Finnish fisheries authorities have implemented three national management strategies setting guidelines for the crayfish introductions. The main aims of the strategies have been conservation of native noble crayfish stocks and a controlled spreading of the alien signal crayfish within a designated region. In this study, we report the current distribution of signal crayfish in Finland in comparison to the guidelines set in these three national strategies. The present distribution area of the signal crayfish covers most of the Southern Finland. The signal crayfish has been introduced with a stocking permits to over 480 water bodies. In addition, there have been numerous stockings without permits, which are often next to the region designated for the signal crayfish. Based on the results, we conclude that crayfish management strategies adopted in Finland have only had limited effect on the spread of signal crayfish. We presume that main causes for the uncontrolled spreading of the signal crayfish in Finland have been lack of strict official supervision and general lack of awareness about the risks associated with the alien species spreading.
Analysis of an augmented fully-mixed formulation for the coupling of the Stokes and heat equations
Authors: Caucao Sergio , Gatica Gabriel N. , Oyarzúa Ricardo
Published: May 2018

We introduce and analyse an augmented mixed variational formulation for the coupling of the Stokes and heat equations. More precisely, the underlying model consists of the Stokes equation suggested by the Oldroyd model for viscoelastic flow, coupled with the heat equation through a temperature-dependent viscosity of the fluid and a convective term. The original unknowns are the polymeric part of the extra-stress tensor, the velocity, the pressure, and the temperature of the fluid. In turn, for convenience of the analysis, the strain tensor, the vorticity, and an auxiliary symmetric tensor are introduced as further unknowns. This allows to join the polymeric and solvent viscosities in an adimensional viscosity, and to eliminate the polymeric part of the extra-stress tensor and the pressure from the system, which, together with the solvent part of the extra-stress tensor, are easily recovered later on through suitable postprocessing formulae. In this way, a fully mixed approach is applied, in which the heat flux vector is incorporated as an additional unknown as well. Furthermore, since the convective term in the heat equation forces both the velocity and the temperature to live in a smaller space than usual, we augment the variational formulation by using the constitutive and equilibrium equations, the relation defining the strain and vorticity tensors, and the Dirichlet boundary condition on the temperature. The resulting augmented scheme is then written equivalently as a fixed-point equation, so that the well-known Schauder and Banach theorems, combined with the Lax-Milgram theorem and certain regularity assumptions, are applied to prove the unique solvability of the continuous system. As for the associated Galerkin scheme, whose solvability is established similarly to the continuous case by using the Brouwer fixed-point and Lax–Milgram theorems, we employ Raviart–Thomas approximations of orderkfor the stress tensor and the heat flux vector, continuous piecewise polynomials of order ≤k+ 1 for velocity and temperature, and piecewise polynomials of order ≤ k for the strain tensor and the vorticity. Finally, we derive optimala priorierror estimates and provide several numerical results illustrating the good performance of the scheme and confirming the theoretical rates of convergence.
Influence of coronal mass ejections on parameters of high-speed solar wind: a case study
Authors: Shugay Yulia , Slemzin Vladimir , Rodkin Denis , Yermolaev Yuri , Veselovsky Igor
Published: May 2018

We investigate the case of disagreement between predicted and observed in-situ parameters of the recurrent high-speed solar wind streams (HSSs) existing for Carrington rotation (CR) 2118 (December 2011) in comparison with CRs 2117 and 2119. The HSSs originated at the Sun from a recurrent polar coronal hole (CH) expanding to mid-latitudes, and its area in the central part of the solar disk increased with the rotation number. This part of the CH was responsible for the equatorial flank of the HSS directed to the Earth. The time and speed of arrival for this part of the HSS to the Earth were predicted by the hierarchical empirical model based on EUV-imaging and the Wang-Sheeley-Arge ENLIL semi-empirical replace  model and compared with the parameters measured in-situ by model. The predicted parameters were compared with those measured in-situ. It was found, that for CR 2117 and CR 2119, the predicted HSS speed values agreed with the measured ones within the typical accuracy of ±100 km s−1. During CR 2118, the measured speed was on 217 km s−1 less than the value predicted in accordance with the increased area of the CH. We suppose that at CR 2118, the HSS overtook and interacted with complex ejecta formed from three merged coronal mass ejections (CMEs) with a mean speed about 400 km s−1. According to simulations of the Drag-based model, this complex ejecta might be created by several CMEs starting from the Sun in the period between 25 and 27 December 2011 and arriving to the Earth simultaneously with the HSS. Due to its higher density and magnetic field strength, the complex ejecta became an obstacle for the equatorial flank of the HSS and slowed it down. During CR 2117 and CR 2119, the CMEs appeared before the arrival of the HSSs, so the CMEs did not influence on the HSSs kinematics.