bluuebunny/crossref_metadata_2025 huggingface dataset:
Chest X-Ray–Based Telemedicine Platform for Pediatric Tuberculosis Diagnosis in Low-Resource Settings: Development and Validation Study
Authors: Gómez-Valverde Juan J , Sánchez-Jacob Ramón , Ribó José Luis , Schaaf H Simon , García Delgado Lara , Hernanz-Lobo Alicia , Capellán-Martín Daniel , Lancharro Ángel , Augusto Orvalho , García-Basteiro Alberto L , Santiago-García Begoña , López-Varela Elisa , Ledesma-Carbayo María J
Published: April 2024

Background

Tuberculosis (TB) remains a major cause of morbidity and death worldwide, with a significant impact on children, especially those under the age of 5 years. The complex diagnosis of pediatric TB, compounded by limited access to more accurate diagnostic tests, underscores the need for improved tools to enhance diagnosis and care in resource-limited settings.

Objective

This study aims to present a telemedicine web platform, BITScreen PTB (Biomedical Image Technologies Screen for Pediatric Tuberculosis), aimed at improving the evaluation of pulmonary TB in children based on digital chest x-ray (CXR) imaging and clinical information in resource-limited settings.

Methods

The platform was evaluated by 3 independent expert readers through a retrospective assessment of a data set with 218 imaging examinations of children under 3 years of age, selected from a previous study performed in Mozambique. The key aspects assessed were the usability through a standardized questionnaire, the time needed to complete the assessment through the platform, the performance of the readers to identify TB cases based on the CXR, the association between the TB features identified in the CXRs and the initial diagnostic classification, and the interreader agreement of the global assessment and the radiological findings.

Results

The platform’s usability and user satisfaction were evaluated using a questionnaire, which received an average rating of 4.4 (SD 0.59) out of 5. The average examination completion time ranged from 35 to 110 seconds. In addition, the study on CXR showed low sensitivity (16.3%-28.2%) but high specificity (91.1%-98.2%) in the assessment of the consensus case definition of pediatric TB using the platform. The CXR finding having a stronger association with the initial diagnostic classification was air space opacification (χ21>20.38, P<.001). The study found varying levels of interreader agreement, with moderate/substantial agreement for air space opacification (κ=0.54-0.67) and pleural effusion (κ=0.43-0.72).

Conclusions

Our findings support the promising role of telemedicine platforms such as BITScreen PTB in enhancing pediatric TB diagnosis access, particularly in resource-limited settings. Additionally, these platforms could facilitate the multireader and systematic assessment of CXR in pediatric TB clinical studies.
R v Sharma’s “Clarification” of the Section 15 Framework and its Creation of Unique Barriers for Disability-Based Equality Claims
Authors: Salvino Caitlin
Published: April 2024

This article analyzes the re-framing of the section 15(1) test in Sharma and its potential implications for future equality rights claimants. After identifying the various ways in which Sharma altered the section 15(1) equality rights framework, it argues that this reframing poses unique and problematic challenges for disability-based equality claims.
Anesthesia in Renal Transplant
Authors: Kurniawaty Juni , Ancilla Cornelia , Arovah Novita Intan
Published: April 2024

Background: Transplantation provides near-normal life and excellent rehabilitation compared to dialysis and is the preferred method of treating end-stage renal disease (ESRD) patients. Methods: We conducted a retrospective analysis of anesthesia management from 20 cases of live renal transplants carried out between August 2017 and April 2019 at Dr. Sardjito Central General Hospital, Yogyakarta. The subjects ' preoperative patient status, anesthesia management, and postoperative care were assessed. Results: Most patients had preoperative anemia, normal serum potassium, serum creatinine, and average ejection fraction. Anesthesia management began 24 hours before surgery, in which the patients were hospitalized, had peripheral IV access and fluid maintenance, and hemodialysis, followed by premedication 1 hour before surgery. Before surgery, anesthesia induction and intubation were done, followed by maintenance of anesthesia and intraoperative monitoring. Postoperative care consisted of the administration of analgesia and management of complications. Conclusion: Optimization of preoperative status, proper anesthesia management, and good postoperative care are keys to a successful renal transplant program.
Penyakit Paru Obstruktif Kronis (PPOK) dengan Multipel Komorbid
Authors: Maryani Nova , Akhmad Yun  Jufan  , Bowo Adiyanto
Published: April 2024

Pendahuluan: PPOK merupakan penyakit yang sering, dapat dicegah dan dapat diobati, namun sering tidak terdiagnosa dan misdiagnosa sehingga pasien tidak mendapatkan pengobatan atau pengobatan yang tidak tepat.

Kasus: Seorang laki-laki usia 76 tahun rujukan dari rumah sakit tipe D dengan diagnosa PPOK dengan CAP, AKI, dan CHF cf III dan membutuhkan hemodialisa. Pasien datang ke rumah sakit sebelumnya dengan keluhan sesak nafas 1 bulan yang lalu dan memberat 1 minggu SMRS, sesak nafas dirasakan memberat saat aktifitas, keluhan disertai batuk (+) berdahak warna putih. 1 minggu SMRS pasien dirawat di RS perujuk, karena keluhan sesak memberat pasien dilakukan intubasi dan dirawat di ICU di RS perujuk selama 1 hari. Pasien kemudian dirujuk ke RSS dan dilakukan perawatan di ICU selama 12 hari, kemudian dilanjutkan perawatan di HCU.

Diskusi:

Penggunaan intubasi dan weaning pada pasien PPOK sangat menarik dan menantang. Pasien selama 12 hari perawatan di ICU diberikan medikamentosa sesuai diagnosa dan manajemen ventilasi dengan pemberian NIV diselang seling dengan NRM setelah pasien autoextube pada hari ke-5. Rontgen thorax terakhir menunjukkan perbaikan pada pneumonia dan edem pulmo, sehingga pasien dipindah di HCU untuk perawatan selanjutnya. Problem pasien dengan PPOK dan proses menyapih dari ventilator dapat membutuhkan waktu yang lama. Kesabaran intesivis dan pasien dibutuhkan dalam proses ini.

Kesimpulan:

PPOK yang didiagnosa disertai dengan komorbid penyakit lainnya dapat menyulitkan untuk proses perawatan dan weaning ventilator jika pasien menggunakan ventilator ketika masuk di ICU.

 

Kata Kunci: COPD, Cor Pulmonale, ICU
Blok Pleksus Servikalis Superfisialis pada Insisi Abses Submandibula
Authors: Krisna Bayu Timor , Wisudarti Calcarina Fitriani Retno , Sudadi  , Ikhsan Isroful , Farid Anisa Fadhila
Published: April 2024

This case study explores the use of bilateral superficial cervical plexus block as a regional anesthesia method in a 44-year-old male patient with a submandibular abscess. The patient, who has comorbidities of type 2 diabetes mellitus, renal insufficiency, and grade 1 obesity, underwent a 60-minute abscess drainage incision operation. This technique was chosen based on patient factors and the medical team's preference, avoiding the risks associated with general anesthesia. Lidocaine 2% at 6cc per side was used, demonstrating the effectiveness of the cervical plexus block in this procedure and others such as lymph node dissection and laceration repair. The study confirms that regional anesthesia guided by ultrasound is a quick, resource-efficient, and safe option, with the potential to avoid improper analgesic dosing. For longer procedures, local anesthetics like ropivacaine or bupivacaine can be utilized. The main conclusion is that the superficial cervical plexus block is an effective and safe alternative for anesthesia in certain neck procedures.
MLCompare: Platform to Compare Machine Learning Models
Authors: Vinod Pal Sonam
Published: April 2024

Abstract: The field of machine learning (ML) continues to advance, the demand for efficient and effective methods for model development and selection becomes increasingly pressing. Automated Machine Learning (AutoML) platforms have emerged as powerful tools to address this need by automating the process of model selection, hyperparameter tuning, and feature engineering. By integrating a wide array of ML techniques and leveraging cloud computing resources, the platform enables researchers and practitioners to efficiently explore and compare the performance of various algorithms across diverse datasets. Key features include a user-friendly interface, a robust evaluation framework encompassing traditional metrics and advanced techniques, and parallel processing capabilities. Through experiments on benchmark datasets from multiple domains, the platform demonstrates its ability to streamline algorithm selection and provide valuable insights into algorithm performance. This contribution advances the field of AutoML by facilitating informed decision-making and accelerating innovation in ML applications.
Prolific Career Path: ML-based Career Guidance
Authors: Patil Minal V. , Khodaskar Dr. Anuja A. , Mohane Bhagyashree G. , Wasankar Snehal W. , Lekurwale Trushali A. , Naik Pratiksha R. , Monde Anmol S.
Published: April 2024

Abstract: The system titled “Prolific Career Path: ML-based Career Guidance” presents a detailed career path for the students who confused about their career. Most of the students across the globe are always in confusion after they complete higher secondary and therefore, the stage where they need to settle on an appropriate career path. The students don't have adequate maturity to accurately understand what a private has to follow to decide on a congenial career path. The system aims to Introducing the Career Guidance System enables students to choose the career path best suited to their personality, interests, and skills without much efforts The system providing MCQ based tests for secondary students as well as for higher secondary students according to their previous field. So in our system we have used an logistic regression for predicting the best career field for students according to their interests.
Un efecto novedoso del extracto acuoso de semillas de Pimpinella anisum sobre garrapatas de perros domésticos (Canis lupus familiaris)
Authors: Várguez-Tec William Fernando , Nahuat-Dzib Sara Luz , Cano-Sosa Julia , Reyes-Vaquero Lorena , Lara-Ramírez Edgar E. , Ayil-Gutierrez Benjamín Abraham , Domínguez-May Angel Virgilio
Published: April 2024

Los pesticidas sintéticos utilizados para combatir las garrapatas pierden su eficacia contra determinadas especies y pueden afectar la salud humana. En el presente estudio se evaluó in vitro e in vivo el efecto del extracto acuoso de semillas de Pimpinella anisum (P. anisum) contra Rhipicephalus sanguineus e Ixodes affinis, garrapatas del perro doméstico. En las evaluaciones in vitro se aplicaron directamente a las garrapatas concentraciones de 1.25, 2.5, 5, 10, 25, 50, 75 y 100 % del extracto acuoso de P. anisum. Las concentraciones que provocaron mayor efectividad en la inmovilización fueron 50%, 75% y 100%, pero esta última provocó una inmovilización por mayor tiempo (55.89 ± 0.16 min). En la evaluación in vivo, el extracto acuoso concentrado se aplicó sobre garrapatas adheridas a la piel de perros domésticos. Se utilizó Amitraz, un garrapaticida comercial, como testigo positivo. Tanto el extracto acuoso concentrado como el Amitraz provocaron el 100 % del desprendimiento de garrapatas. Sin embargo, el extracto acuoso concentrado de semillas de P. anisum fue más efectivo para reducir el tiempo promedio de desprendimiento de las garrapatas (60.81 ± 3.17 min) en comparación con el garrapaticida comercial Amitraz (145.12 ± 15.97 min). Esta investigación sugiere que el p-anisaldehído identificado en el extracto acuoso podría estar relacionado con la inmovilización y desprendimiento de R. sanguineus e I. affinis de los perros domésticos, lo que sugiere que este extracto podría usarse como biopesticida para controlar las garrapatas en perros domésticos.
EFFECT OF DIFFERENT DRINKS ON STAINABILITY OF ACRYLIC DENTURE TEETH
Authors: Md Jasin Naziah , Roslan Husniyati , Adin Noayu , Suhaimi Fatanah Mohamad , Fairuz Omar Ahmad
Published: April 2024

Acrylic denture teeth may experience colour change after some time in service. The aim of this study was to evaluate the discolouration of the acrylic denture teeth when immersed in tea and cola solutions. These solutions were chosen as they are the daily drink by most Malaysians despite of the age based on surveys in Malaysia. 45 first maxillary anterior acrylic denture teeth were divided into three groups (n=15): control (distilled water), tea and cola solutions. The colour changes were recorded after Day 1, Day 7, Day 15 and Day 30 using Coral dental shade guide and visible spectrometer. The visible spectrometry analysis showed that there is a relatively distinctive feature between reflectance from samples immersed in tea and cola. There is strong indication of colour changes for the samples immersed in tea compared to cola, particularly for wavelength between 400-500 nm after 30 days. The result shows that acrylic teeth became slightly darker when immersed in the tea solution for 15 days and 30 days. Average discolouration of the acrylic teeth on day 15 was 1.1333 (SD 0.3519) and day 30 was 1.4467 (SD 0.5164). On the contrary, teeth immersed in cola did change colour but became slightly brighter. The colour change is insignificant, indicating the stable properties of acrylic denture teeth colour and they were not influenced by extrinsic factors. The discolouration of acrylic resin denture teeth was time dependent and increased proportionally with the immersion period.
PREVENTING THE RESURGENCE OF COVID-19 PANDEMIC AND SIMILAR EPIDEMICS: THE NEED FOR ONE HEALTH APPROACH
Authors: Chidinma Okpua Nelson , Mohd Shariff Noorsuzana , Hami Rohayu , Mohd Mujar Noor Mastura
Published: April 2024

Epidemiological evidences over the decades suggest that about 60% to 75% of emerging human infectious diseases are transmitted by animals, especially wildlife. This is as a result of the increasing interface between human, wild animals and environment caused by the destruction of natural habitats by human activities and climate change. The recent link of COVID-19 to the seafood and animals’ market in Wuhan China, and the 98.99% shared resemblance of the virus to the genetic sequence of bat coronavirus holds a strong suspicion for zoonotic transmission. However, efforts towards controlling the pandemic have been centered on human health, with little or no attention on the animal and environment hosts. This paper proposes one health approach as a strategy that could control the resurgence of COVID-19 and similar zoonotic diseases outbreak.
And _ Blinkbonny Avenue and strangeness of everyday life
Authors: Niina Marjatta Turtola
Published: April 2024

This is a research project into building an artist book that uses typographic devices and page layout in construction a multilayered narrative. Everyday life and actual events are part of of the narrative backbone and this is mostly photographic material. Another layer consists on dialogues (verbal, email, etc) between 2015- and ongoing between the two researchers involved in the project. This is language-based written material. Third layer is the thematic context in building the actual book which happens in the academic presentations, performances and knowledge disseminations.
A perspective on the European Health Data Space
Authors: Julesz Máté
Published: April 2024

At the time of writing this article, the European Health Data Space (EHDS) is under development. A legal definition of the primary and secondary use of health data at the supranational level is a given; however, the practice of cross-border e-health still needs to be both legally and technically reinforced. Healthcare equality and technological justice need to be observed when legislating on e-health at the national and supranational levels. Data altruism is a positive phenomenon in the secondary use of health data; nonetheless, the unethical exploitation of the health-related data of digital citizens living with a chronic illness or other ailments should be eliminated. While the extension of the European digital society to include other digital societies as a whole might happen in the far future, the early results of the already interconnected European e-health infrastructures are promising. Nevertheless, there is much to do to ensure patient safety via e-health.
Science Fiction in Ukraine: 1920–2020
Authors: Shynkarenko Oleh
Published: April 2024

The variability in the genre of Ukrainian science fiction (SF) has always been determined by the requirements of the time and the political situation. That is why the fiction of the 1920s promoted the ideology of naive techno-communism, but during the next forty years it became obvious that the Soviet project had reached a dead end, and its positivist component had not brought the desired results. Ukrainian SF writers then turned to mysticism and denial of a rational view of the world.
Key design aspects of a wind turbine SRB main bearing for field operation performance
Authors: Gao Xuehai , Wang Xun , Zhang Zekun
Published: April 2024

A main bearing (MB) preforms the critical role of supporting the rotor
and whole drive train in a wind turbine. It endures very heavy and
complex load coming from the rotor, meanwhile, high reliability in whole
operation life is required for the high cost of MB replacement. Taking a
spherical roller bearing (SRB) MB as an example, the paper analyzed
complex load characters of a SRB MB configuration and discussed how to
simplify the complex load in MB design works, then the key aspects
influencing the MB performance were discussed, including raceway
performance and shrink fit. Further more, thresholds of raceway contact
pressure occurrence, fitting contact pressure and hoop stress were
presented based on the state of art experiences. The paper gives an
overview of SRB MB design for field operation performance.
Long-range earthquake energy-release process under locally homogeneous conditions between 2007-2014 at northern Chile
Authors: Toledo Patricio A , Riquelme Sebastián , Siegel Cristián , Madariaga Raúl , Campos Jaime
Published: April 2024

The seismic cycle in subduction zones comprehends a phenomena of
build-up and release of strain, which is punctuated by the occurrence of
earthquakes. Nonetheless, the occurrence of earthquakes themselves
depends on the relative plate velocity and on lateral heterogeneities
that ponderate the energy release. This characteristic is exploited in
order to obtain a seismic cycle representation in Northern Chile, using
data from the IPOC catalog in the years 2007–2014. We propose and
evaluate a scaling relationship for the energy released by earthquakes
in a determined scale, depending on the elastic modulus, earthquake
displacement and mean stress drop. Displacement, on the other hand, is
obtained assuming that the seismicity rate is locally homogeneous and
that the averaged regional balance process, which counters tectonic
displacement in time due to plates relative velocity with the cumulative
sum of earthquake displacements, washes out on the long term. This
framework allowed us to obtain a seismic cycle representation between
megathrust earthquakes from 2007 and 2014, accounting for a variety of
phenomena observed.
Mycoparasitism in Basidiomycota
Authors: Schoutteten Nathan , Begerow Dominik , Verbeken Annemieke
Published: April 2024

Among the over 31,000 recognized species within Basidiomycota,
approximately 200 are documented as parasites of other fungi, so-called
mycoparasites. They exhibit a remarkable diversity in morphological
characteristics, host-parasite interaction structures, and phylogenetic
affiliations. Mycoparasitism as a trophic strategy in Basidiomycota has
received little attention from the mycological community, with most
research performed during the last decades of the previous century.
These mycoparasites are documented across three subphyla, encompassing
10 different classes, yet a comprehensive understanding of their
evolutionary relationships and host-parasite interaction mechanisms
remains limited, and much data are scattered in the literature. This
chapter aims to systematically outline the various classes of
Basidiomycota known to include mycoparasites, elucidating their
diversity, host-parasite interface, life cycle, morphology, and
systematic classification. To provide a comprehensive overview of
current knowledge on basidiomycetous mycoparasitism, we have compiled a
catalogue of presumed mycoparasites, detailing available data for each
species.
Smart Tourism Ecosystem Development Readiness in Southeast Asia
Authors:   Asian Development Bank, Weltman Trevor , Sciacca Angelo ,   Asian Development Bank, Hwang Yeong-Hyeon ,   Dong-A University, Schipani Steven ,   Asian Development Bank
Published: April 2024

This brief tracks how Southeast Asian countries are using smart technologies to make their tourism sectors more competitive, inclusive, and sustainable, and outlines the complex financing and infrastructure challenges they face. The brief shows how integrated technology can be harnessed by the tourism sector for uses from e-visas to smart waste management and cashless payments, benefiting businesses, consumers, and destinations alike. With Thailand topping its smart tourism readiness table, the brief explains how countries should look to narrow the digital divide, tweak policies, and pull in private sector financing to provide tourists the convenient digital solutions they increasingly expect.
THE LENGTH-WEIGHT RELATIONSHIP OF Butis sp. IN THE TAMBUN RIVER, TOLITOLI DISTRICT, CENTRAL SULAWESI
Authors: Laheng Suardi , Putri Dwi Utami , Febriani Febriani
Published: April 2024

Butis sp. is a type of fish that possesses physical characteristics such as small scales and a yellowish belly. Information regarding the existence and growth of this type of fish is still limited to the Tambun River, Tolitoli Regency. Analyzing the length and weight of the fish is one of the methods used to determine the biological conditions and fish stocks, there by facilitating the management of biodiversity sustainability. The aim of this study was to determine the relationship between the length and weight of Butis sp. in order to understand fish growth patterns. This research was carried out for 2 months in Sungai Tambun, Tolitoli Regency, Central Sulawesi Province. The location for collecting sample were   divided into 3 stations. The test parameters observed were the relationship between length and weight and habitat conditions. The research results of Butis sp. in Sungai Tambun, Tolitoli Regency showed a positive allometric growth pattern (b= 3,25). The water quality in the Tambun River still supports the growth of Butis sp. (temperature 25-28oC, pH 5,5-8,5).Keywords : Biodiversity, fish biology, growth, positive allometrics
INTERACTION OF STOCKING DENSITY AND DIFFERENT PLANT TYPES IN CULTIVATING SANGKURIANG CATFISH (Clarias gariepinus var. Sangkuriang) AQUAPONIC TECHNOLOGY
Authors: Dg. Masese Risa Apriana A. , Ndobe Samliok , Widiastuti Irawati Mei
Published: April 2024

This study investigated the impact of varying stocking densities and plant species interactions within an aquaponic framework. Conducted over a 45-day period (August-October 2023) at the Experimental Farm of Tadulako University, Palu, Central Sulawesi, the research utilized juvenile Sangkuriang catfish (Clarias gariepinus var. Sangkuriang) as the focal organism. Employing a factorial design, with stocking densities 12, 20, and 28 fish per 40 liters of water and three distinct plant species (Ipomoea aquatica, Brassica rapa subsp. chinensis, and Lactuca sativa), the study aimed to elucidate optimal growth conditions. Key findings revealed that the stocking density of 12 fish per 40 liters of water, coupled with pakchoi plants, yielded the most significant growth enhancements. Specifically, this configuration demonstrated a specific growth rate of 6.66±0.7% and absolute weight growth of 14.06±1.0, along with a specific length growth rate of 2.10±0.6% and absolute length growth of 4.48±0.6%. Notably, water quality parameters remained within acceptable limits across all treatments, ensuring an environment conducive to catfish growth. In conclusion, this research underscores the critical role of stocking density and plant selection in optimizing aquaponic systems. The findings offer valuable insights into enhancing both fish and plant growth dynamics within integrated aquaponic frameworks. Keywords: Catfish farming, aquaponics, growth rate, survival rate.
Evaluation of Post Tension Runway Plate as Retrofitting Simulated with Compression In-Plane Force in Numerical Approach
Authors:   Fakultas Teknik dan Ilmu Komputer, Universitas Bakrie, Jakarta, Indonesia, Fachrur Reza Muhammad Daffa , Alisjahbana Sofia W ,   Fakultas Teknik dan Ilmu Komputer, Universitas Bakrie, Jakarta, Indonesia, Furqan Muhammad Nuzulul ,   Fakultas Teknik dan Ilmu Komputer, Universitas Bakrie, Jakarta, Indonesia
Published: April 2024

The swelling of soil can result from fluctuations in its moisture content, causing it to expand and contract. To mitigate this, structures in direct contact with the soil may require retrofitting. Post-tensioning is one such method that can enhance the stiffness of the structure without altering its properties, thereby helping to prevent damage from expansive soil. This research presents a novel methodology for the design of retrofitting runway pavements using post-tension plates, employing a numerical approach that considers various influencing factors. The methodology integrates the use of differential and Kerr foundation equations, employing the Levy method to ascertain the deflection of the plate structure. Soil parameters are derived from soil sampling and laboratory tests, while loads are determined based on prior research findings and governmental regulations. The findings of the study indicate that the thickness of the plate structure influences its deflection, as greater thickness results in increased stiffness within the structure. Increasing the thickness of the plate enhances stiffness and diminishes deflection. Regarding the direction of post-tensioning, employing tension in both directions proves most effective, resulting in a reduction of deflection by 22.11%. However, this model demands higher costs compared to others due to the increased requirement for tendon post-tensioning. As an alternative, aligning the direction of post-tensioning with the direction of load movement can lead to a reduction of 15.14% in plate deflection, while incurring lower costs compared to applying post-tensioning in both directions.
Probability of Failure for Fixed Offshore Structures Determination: An Analysis of a Braced Monopod and 4-Legged Platforms with Respect to Industry Standards
Authors:   Hibiscus Oil and Gas Malaysia Limited, Kuala Lumpur, Malaysia, Mat Soom Ezanizam , Mohamad Mazlina ,   School of Civil Engineering, College of Engineering, Universiti Teknologi MARA, Shah Alam, Malaysia, Abu Husain Mohd Khairi ,   Razak Faculty of Technology and Informatics, Universiti Teknologi Malaysia, Kuala Lumpur, Malaysia, Mohd Zaki Noor Izza ,   Razak Faculty of Technology and Informatics, Universiti Teknologi Malaysia, Kuala Lumpur, Malaysia
Published: April 2024

The structural integrity is susceptible to a combination of statistical and engineering design uncertainties that may remain flexible as long as the structure can successfully manage the encountered load. There are many methods for determining the probability of failure (POF) in the oil and gas sector, but they all have particular constraints. Therefore, this study is a quantitative risk assessment to establish a more reliable method for calculating the POF value. This study chose and evaluated a sample of a braced monopod and 4 legged offshore structures for global non-linear analysis. The most reliable form of distribution was predetermined, and the appropriate integral equation was applied and computed based on the load and strength model conditions. The result of the testing of stress-strength interference for 12 directions and for 8 directions of wave impact in POF indicated that the platform remained intact and reliable compared to the L2 exposure level for the reliability target of POF recommended by ISO 19902, ISO 19901, and PETRONAS. Furthermore, this established that the applied integral equation provided a high degree of confidence in calculating the new POF. This newly created approach will enable the structural engineer to outline action items as part of the organisation’s risk management process.
Modernizations of graphene nanocomposites using synthesis strategies—State-of-the-art
Authors: Kausar Ayesha , Ahmad Ishaq
Published: April 2024

Graphene has been ranked among one of the most remarkable nanostructures in the carbon world. Graphene modification and nanocomposite formation have been used to expand the practical potential of graphene nanostructure. The overview is an effort to highlight the indispensable synthesis strategies towards the formation of graphene nanocomposites. Consequently, graphene has been combined with useful matrices (thermoplastic, conducting, or others) to attain the desired end material. Common fabrication approaches like the in-situ method, solution processing, and melt extrusion have been widely involved to form the graphene nanocomposites. Moreover, advanced, sophisticated methods such as three- or four-dimensional printing, electrospinning, and others have been used to synthesize the graphene nanocomposites. The focus of all synthesis strategies has remained on the standardized graphene dispersion, physical properties, and applications. However, continuous future efforts are required to resolve the challenges in synthesis strategies and optimization of the parameters behind each technique. As the graphene nanocomposite design and properties directly depend upon the fabrication techniques used, there is an obvious need for the development of advanced methods having better control over process parameters. Here, the main challenging factors may involve the precise parameter control of the advanced techniques used for graphene nanocomposite manufacturing. Hence, there is not only a need for current and future research to resolve the field challenges related to material fabrication, but also reporting compiled review articles can be useful for interested field researchers towards challenge solving and future developments in graphene manufacturing.
Towards long-term relationship of transport investment and economic growth in Thailand: Implications for public policy in post-COVID-19 investment
Authors: Pechdin Watchara , Swangsilp Sorasich
Published: April 2024

COVID-19 has presented considerable challenges to fiscal budget allocations in developing countries, significantly affecting decisions regarding number of investments in the transport sector where precise resource allocation is required. Elucidating the long-term relationship between public transport investment and economic growth might enable policymaker to effectively make a decision in regard to those budget allocation. Our paper then utilizes Thailand as a case study to analyze the effects on economic growth in a developing country context. The study employs Cointegration and Vector Error Correction Model (VECM) techniques to account for long-term correlations among explanatory variables during 1991–2019. The statistical findings reveal a significantly positive correlation between transport investment and economic growth by indicating an increase of 0.937 in economic growth for every one-percent increment in transport investment (S.D. = 0.024, p < 0.05). This emphasizes the potential of expanding the transport investment to recover Thailand’s economy. Furthermore, in terms of short-term adjustments, our results indicate that transport investment can significantly mitigate the negative impact of external shocks by 0.98 percent (p < 0.05). These findings assist policymakers in better managing national budget allocations in the post-Covid-19 period, allowing them to estimate the duration of crowding-out effects induced by shocks more effectively.
The Business Model of Industrial Networks in the Context of the Industry 4.0 Environment
Authors: GRABOWSKA Sandra , SANIUK Sebastian
Published: April 2024

The article presents a business model based on an industrial network of companies capable of producing personalized products in an Industry 4.0 environment. Based on research conducted in Poland, in manufacturing companies, the critical problems associated with the implementation of Industry 4.0 technologies and the expected benefits associated with their implementation are addressed. The model’s task is to integrate a customer expecting personalized production with a network of companies with the appropriate production resources. The original achievement is the integration of the customer and the manufacturer around an e-business platform, which allows the rapid prototyping of a network of SME companies capable of realizing personalized production. The proposed model describes the architecture of enterprise cooperation under the conditions of implementing the Industry 4.0 concept and is dedicated to the SME sector. The model provides a basis for building prototypes of e-business platforms of small and medium-sized enterprises.
Short-term Fluctuations and Fluctuations in the Development Dynamics of Fixed Assets of Industry
Authors: BEISEMBINA Saltanat , BEISENBI Mamyrbek , KISSIKOVA Nurgul , Shukirova Aliya
Published: April 2024

Management and Production Engineering Review (MPER) is a peer-refereed, international, multidisciplinary journal covering a broad spectrum of topics in production engineering and management. Production engineering is a currently developing stream of science encompassing planning, design, implementation and management of production systems. Orientation towards human resources factor differentiates production engineering from other technical disciplines. The journal aims to advance the theoretical and applied knowledge of this rapidly evolving field, with a special focus on production management, organisation of production processes, management of production knowledge, computer integrated management of production flow, enterprise effectiveness, maintainability and sustainable manufacturing, productivity and organisation, modelling and simulation, decision making systems, project management, innovation management and technology transfer, quality engineering and safety at work. Management and Production Engineering Review is published under the auspices of the Polish Academy of Sciences Committee on Production Engineering and Polish Association for Production Management. The main purpose of Management and Production Engineering Review is to publish the results of cutting-edge research advancing the concepts, theories and implementation of novel solutions in modern manufacturing. Papers presenting original research results related to production engineering and management education are also welcomed. We welcome original papers written in English. The Journal also publishes technical briefs, discussions of previously published papers, book reviews, and editorials. Letters to the Editor-in-Chief are highly encouraged.
Development of Renewable Energy Businesses within China’s Green Industry Framework
Authors: KORABAYEV Rustem , KORABAYEV Kazbek
Published: April 2024

The main goal of the research is to develop a set of guidelines for the development of business within the framework of the green industry, in compliance with all current environmental regulations, as applied to the realities of the current economic situation in China. The methodology basis is a combination of system analysis of the key principles of business development within the framework of environmental strategy in China with a comprehensive analysis of green industry concept as a factor limiting the activities of enterprises to avoid environmental pollution. The results obtained in the research indicate the presence of significant results in the interaction of government and business in the framework of mutually beneficial collaboration for the growth of the green industry. Chinese business structures invest in the development of “green” industrial and manufacturing technologies while ensuring the necessary level of environmental protection.
Right ventricular dysfunction in chronic heart failure: clinical laboratory and echocardiographic characteristics. (the RIVED-CHF registry)
Authors: Palazzuoli Alberto , Dini Frank Loyd , Agostoni PierGiuseppe , Cartocci Alessandra , Morrone Francesco , Tricarico Lucia , Correale Michele , Mercurio Valentina , Nodari Savina , Severino Paolo , Badagliacca Roberto , Barillà Francesco , Paolillo Stefania , Filardi Pasquale Perrone ,   Italian Heart Failure Study Group, Italian Society of Cardiology
Published: April 2024

Background:

Right ventricular dysfunction (RVD) and pulmonary hypertension have been recognized as two important prognostic features in patients with left side heart failure. Current literature does not distinguish between right heart failure (RHF) and RVD, and the two terms are used indiscriminately to describe pulmonary hypertension and RVD as well as clinical sign of RHF. Therefore, the right ventricle (RV) adaptation across the whole spectrum of left ventricular ejection fraction (LVEF) values has been poorly investigated.

Methods:

This is a multicenter observational prospective study endorsed by the Italian Society of Cardiology aiming to analyze the concordance between the signs and symptoms of RHF and echocardiographic features of RVD. The protocol will assess patients affected by chronic heart failure in stable condition regardless of the LVEF threshold by clinical, laboratory, and detailed echocardiographic study. During the follow-up period, patients will be observed by direct check-up visit and/or virtual visits every 6 months for a mean period of 3 years. All clinical laboratory and echocardiographic data will be recorded in a web platform system accessible for all centers included in the study.

Results:

The main study goals are: to investigate the concordance and discordance between clinical signs of RHF and RVD measured by ultrasonographic examination; to evaluate prognostic impact (in terms of cardiovascular mortality and heart failure hospitalization) of RVD and RHF during a mean follow-up period of 3 years; to investigate the prevalence of different right ventricular maladaptation (isolated right ventricular dilatation, isolated pulmonary hypertension, combined pattern) and the related prognostic impact.

Conclusions:

With this protocol, we would investigate the three main RVD patterns according to heart failure types and stages; we would clarify different RVD and pulmonary hypertension severity according to the heart failure types. Additionally, by a serial multiparametric analysis of RV, we would provide a better definition of RVD stage and how much is it related with clinical signs of RHF (ClinicalTrials.gov Identifier: NCT06002321).
Down-regulation of neuronal form of Nitric oxide synthase in the Nurse cell of Trichinella spiralis
Authors: Milcheva R. , Hurníková Z. , Todorova K. , Dilcheva V. , Petkova S. , Janega P. , Babál P.
Published: April 2024

The free radical nitric oxide (NO) and Ca2+ are critical regulators of skeletal muscle exercise performance and fatigue. The major source of NO in skeletal muscle cells is the neuronal form of the enzyme Nitric oxide synthase (nNOS). One of the most peculiar characteristics of the Nurse cell of Trichinella spiralis (T. spiralis) is the complete loss of the contractile capabilities of its derivative striated muscle fiber. The aim of the present study was to clarify the expression of nNOS protein and mRNA in striated muscles during the muscle phase of T. spiralis infection in mice. Muscle tissue samples were collected from mice at days 0, 14, 24, and 35 post infection (d.p.i.). The expression of nNOS was investigated by immunohistochemistry, and the expression levels of mRNA of mouse Nitric oxide synthase 1 (Nos1) by real-time PCR. The presence of nNOS protein was still well observable in the disintegrated sarcoplasm at the early stage of infection. The cytoplasm of the developing and mature Nurse cell showed the absence of this protein. At least at the beginning of the Nurse cell development, Trichinella uses the same repairing process of skeletal muscle cell, induced after any trauma and this corroborates very well our results concerning the nNOS expression on day 14 p.i. At a later stage, however, we could suggest that the down-regulation of nNOS in the Nurse cell of T. spiralis either serves a protective function or is an outcome of the genetic identity of the Nurse cell.
CHRONIC BRONCHITIS IN CAT
Authors: Wisnantari Ni Made Suksmadewi , Jayanti Putu Devi , Suartha I Nyoman
Published: April 2024

Chronic bronchitis is an inflammation of the bronchi with symptoms observed for more than 2 months. This report aims to discuss the incidence of chronic bronchitis in domestic cats. The case animal used was a male domestic cat named Roki aged 3 years with a body weight of 3.25 kg. Based on anamnesis, the cat showed complaints of coughing, sneezing and nasal discharge. Coughing complaints have been observed since the last 1 year, while sneezing and nasal discharge complaints have been observed since the last 1 week. Physical examination showed cough and mucopurulent nasal discharge. Radiographic examination showed increased opacity and thickening of the bronchial wall. Routine haematological examination showed the cat had leucocytosis and thrombocytopenia. Cytological examination of nasal discharge showed proliferation of neutrophilic inflammatory cells and bacterial infiltration of Streptococcus sp. The therapy given to the case cat was Amoxicilin trihydrate 125 mg/5 mL (Amoxsan®, PT. Sanbe Farma, Cimahi, Indonesia) given as much as 10 mg/kg BW twice a day for seven days with an amount of 1.3 mL per oral administration. Anti-inflammatory meloxicam 7.5 mg (Meloxicam®, PT Dankos Farma, Jakata, Indonesia) was administered once daily for four days at a dose of 0.1 mg/kg BW orally. Theophylline bronchodilator 130 mg/15 mL (Theobron®, PT. Interbat, East Java, Indonesia) was administered as 10 mg/kg BW once daily for seven days with a total administration of 0.9 mL orally. Supportive therapy was given multivitamins (Curvit®, PT Soho Industri Pharmasi, Jakarta, Indonesia) with an amount of 1.5 mL once a day for seven days. Based on history taking, clinical examination and laboratory tests, the case cat was diagnosed with chronic bronchitis with a prognosis of fausta. The results of 7 days of treatment showed improvement, namely coughing, sneezing and nasal discharge were no longer observed. It is recommended to the cat owner to cage and always maintain the cleanliness of the cat's living environment to prevent the recurrence of chronic bronchitis and the owner needs to pay attention to the food given.
Point of Care Ultrasound Diagnosis of Maxillary Artery Pseudoaneurysm in the Emergency Department
Authors: Alerhand Stephen , Ali Marwa , Beckman Sean
Published: April 2024

A pseudoaneurysm results from a tear in a vessel wall. This leads to extravasation of blood into adjacent tissue and eventual formation of a fibrous sac that maintains continuity with the lumen. These vascular injuries very rarely occur in deeper vessels of the face (e.g. maxillary artery) due to protection from structures like the bony mandible and parotid gland. If left untreated, these pseudoaneurysms can lead to infection, thromboembolism, hemorrhage, and compression of surrounding structures such as facial nerve branches. Pseudoaneurysms are typically diagnosed by advanced imaging techniques including computed tomography angiography and magnetic resonance angiography. However, these tests require time to perform and interpret, are costly, and take place outside the patient care area. Computed tomography also confers ionizing radiation. Fortunately, point of care ultrasound (POCUS) is a readily available, dynamic imaging tool that can be performed at the bedside. Here we present the first known case report of a maxillary artery pseudoaneurysm diagnosed by POCUS in the emergency department. Early differentiation from a typical hematoma led to rapid management in the form of a compression bandage, as well as expedited consultation to the appropriate services.
Point of Care Ultrasound Used to Diagnose Nontyphoidal Endocarditis
Authors: Alqallaf Zahraa Yousef , Maadarani Ossama , Elhabibi Mohamed Elsayed , Abdelfatah Mohamad , Bitar Zouheir
Published: April 2024

Point of care ultrasound (POCUS) can make an expedited diagnosis, which might lead to early correct management. POCUS should be used in a systemic and integrated approach to evaluate multiple organs in patients with sepsis and septic shock. We present a rare case of sepsis due to Salmonella endocarditis with abscess in which a POCUS examination led to expedited treatment.
Diagnosis of Cutaneous Larva Migrans using Point of Care Ultrasound
Authors: Lamour Daniella , Farrow Robert A. , Pierre Jean , Khalil Paul
Published: April 2024

Larva is a cutaneous parasitic infection that occurs when an immature hookworm larva inadvertently penetrates the dermis of a human, typically on the extremities. Traditionally, a clinical diagnosis is made when a tortuous/ eruption is seen superficially in the skin with complaints of intense . Point of care ultrasound (POCUS) is a useful diagnostic tool for soft tissue complaints in the emergency department (ED). We describe a case of an 18-year-old woman who presented to the ED with foot four days after walking on the beach barefoot. POCUS examination revealed several motile structures in the dermis of the patient’s foot, confirming our suspicion of cutaneous larva . The patient was then placed on an oral and her symptoms resolved shortly after.
Karakterisasi Struktur Kumarin pada Akar Tumbuhan Langsat (Lansium domesticum Corr.)
Authors: Nurapita Riska , Rudiyansyah  , Harlia
Published: April 2024

Lansium plants produce not only terpenoids as the main constituent but also contain phenolics on the basis of phytochemical analysis. Unfortunately, there are still limited information about phenolic structures from this plants. This study was conducted to identify one of phenolic structures from chloroform fraction of Lansium domesticum root. The chloroform fraction was fractionated and purified by chromatographic techniques such as vacuum liquid chromatography (VLC) and column chromatography (CC) to obtain a coumarin. Additionally, the coumarin structure was characterized by 1H-NMR. The isolated coumarin showed a positive result for the phenolic test with FeCl3 5%. The 1H-NMR spectrum of isolated coumarin revealed chemical shifts at δH 7,60 (1H, d, J = 9,5 Hz), 6,92 (1H, s), 6,84 (1H, s), 6,27 (1H, d, J = 9,5 Hz), 6,14 (1H, s), and 3,95 (3H, s). Based on those results and comparison with literature data, it can be concluded that the isolated coumarin is iso-scopoletin (1)
The Density Functional Tight Binding (DFTB) Approach for Investigating Vacancy and Doping in Graphene as Hydrogen Storage
Authors: Hidayat Yuniawan , Rahmawati Fitria , Dwi Nugrahaningtyas Khoirina , Bagus Swandito Paulus
Published: April 2024

A study on graphene defects for hydrogen storage has been successfully conducted using the Density Functional Tight Binding (DFTB) approach. The research aimed to modify solid materials for hydrogen storage. A 4 × 4 × 1 unit cell was used as the basis, while the supercell used for sampling was enlarged to 40 × 40 × 1. The analyzed data included changes in Density of States (DOS), Fermi level shifts, electronic band structures, formation energy, adsorption energy, and isosurfaces for each graphene orientation. It has been observed that modifying the surface structure of graphene can alter the electronic properties of graphene. This is indicated by shifts in DOS intensity, characterized by increased electronic intensity around the Fermi level total density charge different. The interaction energy between graphene and hydrogen gas has been determined to be -0.0155 eV for H-epoxy graphene, -0.4941 eV for H-monovacancy graphene, and -0.0424 eV for HN-monovacancy graphene. The presence of the vacancy increase the potential to adsorp hydrogen.