bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring Rhamnus alaternus Polysaccharides: Extraction, Characterization, and Analysis of Antioxidant and Antimicrobial Properties
Authors: Chokri Souha , Ben Younes Sonia , Ellafi Ali , Mnif Sami , López-Maldonado Eduardo Alberto , Slaheddine Masmoudi Ahmed
Published: November 2024

In the present study, polysaccharides were isolated from the leaves (WSPRaL) and stems (WSPRaS) of Rhamnus alaternus with yields of 3% and 3.25% for WSPRaS and WSPRaL, respectively. Crude WSPRaL was composed of proteins (260.740 ± 0.98 µg/mg), lipids (53.34 ± 2.38 µg/mg), total sugars (482.716 ± 3.02 µg/mg), and reducing sugars (420.240 ± 1.68 µg/mg). In contrast, WSPRaS contained proteins (269.629 ± 1.48 µg/mg), lipids (13.33 ± 0.28 µg/mg), total sugars (569.135 ± 3.82 µg/mg), and reducing sugars (531.732 ± 2.59 µg/mg). FTIR, TLC, and HPLC analyses revealed that the carbohydrate fraction of WSPRaS consisted mainly of glucuronic acid, glucose, galactose, xylose, mannose, and arabinose, whereas WSPRaL consisted of galacturonic acid, sucrose, glucose, rhamnose, xylose, mannose, and arabinose. Scanning electron microscopy (SEM) analysis was used to determine the microstructure of the water-soluble polysaccharides. The physicochemical properties were evaluated using Fourier transform infrared (FT-IR) spectroscopy and ultraviolet‒visible (UV‒visible) absorption spectroscopy. The total antioxidant activities of the crude polysaccharides were evaluated using various assays: DPPH radical scavenging (IC50 WSPRaL = 615 ± 2.05 µg/mL, IC50 WSPRaS = 628 ± 2.38 µg/mL), ABTS radical scavenging (470 ± 5.78 µg/mL and 559 ± 4.32 µg/mL for WSPRaL and WSPRaS, respectively), reducing power (IC50 WSPRaS = 141.76 ± 3.16 µg/mL, IC50 WSPRaL = 203.89 ± 1.07 µg/mL), and chelating capacity (IC50 WSPRaS = 225 ± 1.75 µg/mL, IC50 WSPRaL = 219 ± 2.51 µg/mL). In addition, the antibacterial and biofilm inhibitory activities of both polysaccharides were tested against pathogenic strains, and the polysaccharides significantly inhibited plant growth. Overall, the results indicate that the crude polysaccharides extracted from R. alaternus are promising for use as functional and bioactive ingredients in the food and nutraceutical industries. These results highlight the potential of both polysaccharides as natural products in various sectors, including food, cosmetics, pharmaceuticals, and medicine, due to their significant biological properties.
Fostering Critical Thinking About the Critique of Religion: An Empirical Multi-Case Analysis
Authors: Jarmer Sebastian Tjelle
Published: November 2024

Having the right to criticize religion is important for healthy democracies. However, much critique of religion has led to increased levels of polarization. This article explores how religious education can help facilitate critical thinking regarding the critique of religion. By analyzing actual teaching practices about the critique of religion, this article contributes to the field of religious education research in three ways. First, it contributes empirically to the field of religious education, which to a limited degree has studied authentic classroom practices through observations. Second, it contributes theoretically to the field by analyzing which contextual dependencies of teaching facilitate critical thinking about the critique of religion. Third, this study builds on and adds to the prior research about the critique of religion within religious education, which has mainly been theoretical.
Effects of Biochar on Soil Organic Carbon Mineralization in Citrus Orchards
Authors: Ding Zerui , Huang Rui , Li Xianliang , Fan Qijun , Hu Lening , Liu Shengqiu
Published: November 2024

The primary ecological challenges in citrus orchards include soil acidification, nutrient depletion, and significant carbon dioxide emissions resulting from conventional cultivation practices. To address these challenges, citrus peel residues and cassava stalks underwent pyrolysis at 500 °C to generate biochars. Different proportions of these biochars (1%, 2%, and 4%) were applied under controlled laboratory conditions to assess their impact on the mineralization of soil organic carbon in citrus orchards. The results indicated that both types of biochar effectively regulated the soil pH to approximately 5.5. Significantly, the addition of 4% cassava stalk biochar significantly increased the levels of available phosphorus and potassium. The phosphorus levels rose by 512.55%, and the potassium levels surged by 1434.01%. Additionally, the soil organic carbon increased to 16.7 g/kg. Conversely, the citrus peel biochar decreased the availability of phosphorus but resulted in the highest increase in available potassium, at 1523.75%, and elevated the soil organic carbon content to 13 g/kg. Both types of biochar enhanced the soil organic carbon mineralization rate to varying extents with increasing application ratios, simultaneously boosting the cumulative amount of organic carbon mineralized. Among the treatments, cassava stalk biochar displayed the lowest C0/SOC ratio, of 0.169, indicating its superior carbon retention capacity. Furthermore, cassava stalk biochar showed inhibitory effects on soil catalase and urease activities within the citrus orchard. Overall, the application of 4% cassava stalk biochar appears to be more beneficial for nutrient regulation and carbon sequestration in citrus orchard soils, while also contributing to the reduction in soil acidification by adjusting pH levels.
Research on Neutral Dynamic Network Cross-Efficiency Modeling for Low-Carbon Innovation Development of Enterprises
Authors: Liu Zhiying , Wang Danping , Xie Wanrong , Ma Jian , Yang Aimin
Published: November 2024

To evaluate the effectiveness of the low-carbon innovation development of enterprises, this paper proposes a neutral dynamic network cross-efficiency model and introduces the bootstrap sampling method to correct the model. The model categorizes the low-carbon green innovation R&D activities of enterprises into two distinct stages, as follows: the green R&D stage and the results transformation stage. It then assesses the efficiency of each stage and provides an overall efficiency rating. The model has been applied to a sample of listed Chinese iron and steel enterprises (CISES). The results of the study show that the overall efficiency of low-carbon innovation and development of CISES is on the low side, with the highest efficiency achieved in the green R&D stage, which is less than the lowest efficiency attained in the transformation stage, and most of the enterprises are in the stage of high green R&D and low transformation of the results. The ability of marketization of the R&D results still needs to be strengthened.
Revealing the Bioactivities of Physalia physalis Venom Using Drosophila as a Model
Authors: Tomkielska Zuzanna , Frias Jorge , Simões Nelson , de Bastos Bernardo P. , Fidalgo Javier , Casas Ana , Almeida Hugo , Toubarro Duarte
Published: November 2024

Physalia physalis, commonly known as the Portuguese Man o’ War, is one of the most venomous members of the Cnidaria yet is poorly understood. This article investigates the toxicity of P. physalis venom by assessing its behavioral and toxicological effects on Drosophila melanogaster. The venom administered orally revealed dose- and time-dependent mortality, with an LD50 of 67.4 μg per fly. At sublethal doses, the treated flies displayed uncoordinated movement and fell when attempting to climb. Real-time analysis of flies exposed to the venom revealed hyperexcitability followed by paralysis, with phenotypes similar to those observed in vertebrate models. The venom was shown to be non-thermolabile, as no significant differences in behavior and locomotion were observed between flies exposed to untreated or thermally treated venom. The circadian rhythm alterations, the enhanced light attraction, and the reduction in heat avoidance suggest altered neuronal function. This abnormal behavior indicates that the venom contains bioactive molecules, opening avenues for discovering new compounds with potential for pharmacological applications.
Co-Occurrence of Mycotoxins in the Diet and in the Milk of Dairy Cows from the Southeast Region of Brazil
Authors: Borowsky Aline Moreira , Rosim Roice Eliana , Tonin Fernando Gustavo , de Oliveira Carlos Augusto Fernandes , Corassin Carlos Humberto
Published: November 2024

Mycotoxins are toxic fungi secondary metabolites that develop on feedstuffs and can be transferred into milk, thus representing a public health risk. The objective of this study was to assess the co-occurrence of mycotoxins in the diet and in the milk of dairy cows from the southeast region of Brazil. Samples of total mixed ration (TMR, n = 70) and milk (n = 70) were collected in dairy farms and subjected to multi-mycotoxin analysis using liquid chromatography coupled to tandem mass spectrometry. The aflatoxins (AFs), ochratoxin A (OTA), and T-2 and HT-2 toxins were not detected in TMR samples. In contrast, fumonisins (FBs), zearalenone (ZEN), and deoxynivalenol (DON) were detected in 100, 93, and 24% of TMR samples at mean levels of 336.7 ± 36.98, 80.32 ± 16.06 µg/kg and 292.1 ± 85.68 µg/kg, respectively. Ninety-two percent of TMR samples exhibited co-occurring mycotoxins. In milk, 54% of samples (n = 38) had detectable levels of mycotoxin, while 43% (n = 30) contained two or more types of mycotoxins. DON, FB, and ZEN metabolites (α-zearalenol and β-zearalenol) were the most frequent mycotoxins detected in the milk samples analyzed, at mean concentrations of 0.562 ± 0.112, 2.135 ± 0.296 µg/kg, 2.472 ± 0.436 µg/kg, and 0.343 ± 0.062 µg/kg, respectively. However, none of the analyzed milk samples had levels higher than the maximum permitted limit for AFM1 in Brazil (0.5 µg/L). The results of this trial highlight the concern about the co-occurrence of multiple mycotoxins in TMR and in milk, due to the possible additive or synergistic effects of these compounds. The presence of co-occurring mycotoxins in milk underscores the need for stringent preventive practices to avoid mycotoxin contamination in the diet of dairy cows in Brazil.
Cytomegalovirus Infection After Solid Organ Transplantation: How I Use Cell-Mediated Immune Assays for Management
Authors: Razonable Raymund R.
Published: November 2024

Introduction: The pathogenesis and outcome of cytomegalovirus (CMV) infection after solid organ transplantation (SOT) reflects the interplay between viral replication and CMV-specific immunity. Despite advances in its diagnosis and treatment, CMV continues to cause significant morbidity after SOT. Since CMV is an opportunistic pathogen that occurs as a result of impaired pathogen-specific immunity, laboratory assays that measure CMV-specific immune responses may be useful in assisting clinicians in its management. Methods and Results: The author summarizes the evolving and emerging data on the clinical utility of assays that quantify cell-mediated immune responses to CMV in SOT recipients. The majority of publications are observational studies that demonstrate that a lack or deficiency in CMV-specific cell-mediated immunity is correlated with a heightened risk of primary, reactivation, or recurrent CMV after transplantation. A few prospective interventional studies have utilized CMV-specific cell-mediated immune assays in guiding the duration of antiviral prophylaxis among CMV-seropositive SOT recipients. Likewise, CMV-specific cell-mediated immunity assays have been suggested to inform the need for secondary antiviral prophylaxis and immunologic optimization to prevent CMV relapse after treatment. Conclusions: CMV-specific cell-mediated immune assays are emerging to assist transplant clinicians in predicting a patient’s risk of CMV after transplantation, and these assays have been utilized to individualize the approach to CMV prevention and treatment. The author suggests the conduct of more interventional studies to further solidify the role of CMV-specific cell-mediated immune assays in routine clinical practice.
Microplastics Meet Metoprolol in Natural Water: Sorption Behavior and Mechanism
Authors: Peng Tao , Yang Zhuo , Chen Danni , Cao Hongyu , Deng Yuehua , Zhao Wei
Published: November 2024

As an ideal carrier for the spread of pollutants in the aquatic environment, microplastics (MPs) can adsorb pharmaceutical β-blockers, which can affect their migration and lead to some unpredictable adverse consequences. In this paper, the sorption behaviors and mechanism of MPs (polyvinyl chloride (PVC) and polypropylene (PP)) for typical β-blocker metoprolol (MTL) were investigated. The effects of pH, salinity and humic acids (HAs) on the sorption were studied, which proved that the sorption behavior was different under different environmental conditions. Both low pH and high salinity inhibited the sorption of MTL by the MPs. Specifically, the sorption capacity of MTL increased, with pH increase from 3 to 10. When pH = 10, the sorption capacities of MTL on PVC (1.75 mg/g) and PP (3.34 mg/g) reached the maximum. After pH > 10, the amount of MTL adsorbed on PVC was slightly decreased, while that on PP was essentially the same. The addition of salt ions inhibited the sorption in the concentration range of 5–250 mg/g for both NaCl and CaCl2, with the inhibitory effect of Ca2+ being stronger than that of Na+. Moreover, the presence of HAs promoted the sorption of MPs for MTL. In the absence of HAs, the sorption capacities of PP and PVC for MTL were 0.34 mg/g and 0.79 mg/g, respectively. When HA concentration was 100 mg/L, the highest sorption capacities of PP and PVC reached 0.79 mg/g and 1.37 mg/g, respectively. This indicated that the promoting effect of HAs on PP was stronger than that on PVC. In general, based on the study of the sorption behavior of MTL and the characterization of the MPs, the sorption mechanism was speculated to consist mainly of electrostatic interactions, cation exchange, hydrophobic interaction and halogen bonding. The sorption kinetics of MTL on the two MPs were well-fitted by the pseudo-second-order model with R2 > 0.99. The sorption isotherms both fitted the Freundlich model, which substantiated that the sorption of MTL on the MPs (PVC and PP) was multilayered and heterogeneous. Collectively, these findings provided a theoretical basis for revealing the complex interactions between MPs and MTL in natural water and a new insight into the fate and migration of MPs and β-blockers in the environment.
Insights into the Acute Stress of Glutaraldehyde Disinfectant on Short-Term Wet Anaerobic Digestion System of Pig Manure: Dose Response, Performance Variation, and Microbial Community Structure
Authors: Wu Yongming , Li Fangfei , Wu Liuxing , He Shifu , Liang Peiyu , Zhang Lei , Wu Zhijian , Zhang Tao , Liu Yajun , Liu Xiangmin , Huang Xueping , Zhu Lin , Wang Maolin , Deng Mi
Published: November 2024

The outbreak of epidemics such as African swine fever has intensified the use of disinfectants in pig farms, resulting in an increasing residual concentration of disinfectants in environmental media; however, the high-frequency excessive use of disinfectants that damage pig farm manure anaerobic fermentation systems and their mechanisms has not attracted enough attention. Especially, the complex effects of residual disinfectants on anaerobic fermentation systems for pig manure remain poorly understood, thus impeding the application of disinfectants in practical anaerobic fermentation systems. Herein, we explored the effects of glutaraldehyde disinfectant on methane production, effluent physicochemical indices, and microbial communities in a fully automated methanogenic potential test system (AMPTSII). The results show that adding glutaraldehyde led to remarkable alterations in methane production, chemical oxygen demand (COD), volatile solids (VS), and polysaccharide and phosphorus concentrations. During the anaerobic process, the production of methane displayed a notable decrease of 5.0–98% in all glutaraldehyde treatments, and the trend was especially apparent for treatments containing high levels of glutaraldehyde. Comparisons of the effluent quality showed that in the presence of 0.002–0.04% glutaraldehyde, the COD and total phosphorus (TP) increased by 12–310% and 15–27%, respectively. Moreover, the addition of 0.01–0.08% glutaraldehyde decreased the ammonium (NH4+-N) concentration and VS degradation rate by 7.7–15% and 4.9–26.2%. Furthermore, microbiological analysis showed that the glutaraldehyde treatments had adverse effects on the microbial community. Notably, certain functional bacteria were restrained, as highlighted by the decreases in relative abundance and microbial diversity by 1.3–17% and 0.06–21%, respectively. This study provides a theoretical basis for the rational use of disinfectants in anaerobic fermentation systems.
Coupling Coordination Analysis Between Reclaimed Water Utilization Capacity and Effect in China
Authors: Chen Xiaohui , Wu Fengping , Wang Xiaoyu
Published: November 2024

Reclaimed water utilization is one of the major strategies used to achieve sustainable development in China and for alleviating issues linked to insufficient water supply. This study leverages panel data encompassing 30 provinces in mainland China from 2011 to 2022 to establish a comprehensive evaluation index system for measuring the development level of reclaimed water utilization capacity and utilization effect. On the basis of this index, the development rule of coupling coordination between reclaimed water utilization capacity and utilization effect is explored using the coupling coordination degree model, Moran’s I index, and the grey GM (1,1) model. Experimental results show that the current utilization capacity and effect of reclaimed water in most provinces of China do not match. Moreover, China’s reclaimed water utilization capacity index was shown to gradually increase from 2011 to 2022. The reclaimed water utilization capacity index of the eastern region is significantly higher than the central region, which is lower than the national average, followed by the northeast region, and the western region obtains the lowest index. The calculation results of the coupling coordination model further demonstrate the coupling coordination degree between the reclaimed water utilization capacity; moreover, the effects of provinces and cities in China steadily increased, and there is a clear spatial clustering. The predicted results indicate that the abovementioned situation will likely continue until 2030. This study is anticipated to become a point of reference for relevant departments to optimize the coupling coordination degree of reclaimed water systems across different regions in China, implement differentiated measures, and promote a rational allocation of reclaimed water resources.
Detection of human papillomavirus in tissue of inverted nasal papilloma
Authors:   Central City Hospital named after N. A. Semashko, Rostov-on-Don, Russia, Protsenko I. G.
Published: November 2024

The purpose of the study was to identify signs of the presence of human papillomavirus (HPV) and Epstain-Barr virus in inverted papilloma (IP) tissues. HPV DNA was detected by PCR using the MY09 ‑MY11 degenerate primer system. Papillomavirus (common) DNA sequences were detected in all patients with nasal IP. In 8 out of 11 patients with inverted nasal papilloma, oncogenic viruses of types 18, 31 and 33 were detected; in 2 patients, the type specificity of HPV could not be determined, which means that these viruses do not belong to types 6, 11, 16, 18, 31 and 33. In 2 patients with signs of malignant transformation a virological study In 2 patients with signs of malignant transformation the Epstain-Barr virus was revealed and in one of them in association with Papillomavirus (common). The detection of viral infection in biomaterial from IP suggests the possibility of HPV participation in the morphogenetic restructuring of the epithelium, leading to the formation of a tumor.
Place of work and workplace as terms of an employment contract: problematic issues
Authors:   Department of Civil Law Disciplines of MFUA, Moscow, Shuvalova I.A.
Published: November 2024

The article examines the concepts of «place of work» and «workplace», identifies their differences. The problematic issues arising in determining the place of work and workplace for certain categories of employees are analyzed. Based on the conducted research, recommendations are made to amend and supplement some of the legal norms of the Labor Code of the Russian Federation.
Circumstances taken into account by the employer when applying disciplinary sanctions against an employee: trends in judicial practice
Authors:   Department of Labor Law Federal State Budgetary Educational Institution ", Zhiltsova Ju.V. ,   Ural State Law University named after V.F. Yakovlev, Yekaterinburg, Klepalova Ju.I. ,   Department of Civil Law NWF Federal State Educational Institution "Russian State University of Justice", St. Petersburg
Published: November 2024

Of great importance for bringing an employee to disciplinary responsibility in law enforcement and judicial practice are the circumstances that the employer must take into account when applying a disciplinary sanction. The authors of the article, having analyzed the judicial practice, will consider them in detail.
The Impact of Shopping Values on E-Satisfaction and Shopping Wellbeing: A South African Perspective
Authors: Mbulo Valerie Natalie , Ndoro Tinashe Tsungai Raphael
Published: November 2024

Objective: Shopping well-being has continued to be a fundamental construct in retail shopping research. However, marketers seek to understand the factors that enhance shopping well-being for online consumers in the fast-growing era of e-commerce. This study sought to investigate the impact of shopping values (hedonic and utilitarian) and e-satisfaction on shopping well-being within the South African context. Research Design & Methods: The study used a cross-sectional quantitative research design. Using convenience sampling, online survey questionnaires were administered to collect the data from South African consumers who engage in online shopping. Descriptive analysis and multiple regression analysis were used to analyse the data. Findings: The findings of the study indicated hedonic shopping values had a positive impact on shopping well-being. On the other hand, it was found that utilitarian shopping values and e-satisfaction had no positive impact on shopping wellbeing. Implications and Recommendations: From these findings, web-based shopping managers can construct online shopping environments that support hedonic shopping values in order to ensure that consumers shopping online experience shopping wellbeing. Contribution & Value Added: The study adds value to marketing practitioners and businesses that seek to ensure that consumers engaging in online shopping experience satisfaction and wellbeing within the growing e-commerce industry in South Africa and other emerging economies.
The Effect of Financial Literacy, Entrepreneurial Characteristics, and Financial Inclusion on Business Performance
Authors: Kusumawati Dina , Effendi Dwi Erlin
Published: November 2024

Objective: Delays in business management make it difficult for the continued development of MSMEs. This study aims are analyzes financial literacy, entrepreneurial characteristics, and financial inclusion in business performance in processing industry SMEs in Jepara Regency. Research Design & Methods: The data used were obtained from interviews using a questionnaire. The number of samples used was 100 MSME actors selected by the Non-Probability Sampling technique. Data analysis was performed using multiple linear regression analysis methods. Findings: The results showed that financial literacy had a positive and significant effect on business performance, entrepreneurial characteristics had a positive and significant effect on business performance, financial inclusion had a positive and significant effect on business performance, and simultaneously, financial literacy, entrepreneurial characteristics, and financial inclusion had an effect on business performance. Implications and Recommendations: This research implies that the level of financial literacy will affect the making of important decisions in managing business finances, so MSME actors need to increase their financial literacy. The characteristics of a good entrepreneur owned by someone will have a positive orientation toward business performance. Good financial inclusion means that it is easy to use financial services so that they can help overcome problems in their business.
EFEK INFUSUM DAUN KENIKIR (Cosmos caudatus) TERHADAP PERUBAHAN MORFOLOGI DAN TINGKAT KEMATIAN LARVA Aedes aegypti
Authors: Nur Indra Asep Iin , Rahmat Mamat , Sulaeman Sulaeman , Rohayati Rohayati , Sufa Hafizah Ilmi
Published: November 2024

Penyakit Demam Berdarah Dengue (DBD) menjadi masalah kesehatan serius di Indonesia, disebabkan oleh nyamuk Aedes aegypti. Resistensi nyamuk terhadap insektisida kimia meningkat akibat penggunaan yang tidak tepat, sehingga diperlukan alternatif pengendalian vektor, termasuk larvasida alami dari tanaman. Kenikir (Cosmos caudatus) adalah salah satu tanaman yang berpotensi sebagai larvasida, berkat kandungan minyak atsiri dan metabolit sekundernya. Penelitian ini bertujuan menguji pengaruh infus daun kenikir terhadap kematian larva Aedes aegypti dengan variasi konsentrasi dan menentukan konsentrasi efektif sebagai LC50, yaitu yang membunuh 50% larva. Populasi dalam penelitian ini adalah seluruh spesies kenikir yang berasal dari perkebunan Manoko, Lembang, dengan sampel berupa daun kenikir spesies Cosmos caudatus. Sebanyak 315 larva Aedes aegypti diperoleh dari Loka Litbang dan digunakan sebagai objek penelitian. Metode true eksperimen digunakan dengan desain Static Group Comparison, melibatkan kelompok eksperimen dan kontrol. Objek penelitian adalah larva Aedes aegypti instar III yang diuji dengan infus kenikir pada konsentrasi 25%, 35%, 45%, 55%, dan 65%. Hasil menunjukkan bahwa konsentrasi minimum efektif adalah 25%, sedangkan uji probit mengindikasikan konsentrasi 28% sebagai LC50 dalam 24 jam. Kematian larva disebabkan oleh kerusakan selaput luar jaringan, menunjukkan efek ekstrak kenikir, bukan karena kekurangan makanan.
Djelovanje biskupa Ratka
Perića u svjetlu diplomatskih izvješća na WikiLeaksu
Authors: Vidović Danijel , Ivić Anto
Published: November 2024

Članak tematizira odnos međunarodnih protektora u BiH prema mostarsko-duvanjskom biskupu i trebinjsko-mrkanskom apostolskom upravitelju Ratku Periću (koadjutor 1992. – 1993., ordinarij 1993. – 2020.) u vremenu velikih političkih previranja i udara na politički subjektivitet hrvatskog naroda u BiH početkom dvijetisućitih. Rad stavlja poseban naglasak na američke diplomatske izvještaje koji su postali javno dostupni zahvaljujući bazi WikiLeaksa. Analizom sedam izvješćâ američkih diplomata na službi u veleposlanstvima u Sarajevu i Vatikanu osvjetljava se višegodišnja diplomatska aktivnost, koja je primarno vođena iz State Departmenta, a uključivala je i američke diplomate angažirane u međunarodnim organizacijama poput UN-a i OSCE-a, kao i pojedine zapadne administracije poput britanske i francuske. Uvidom u ovu dokumentaciju otkrivaju se neki detalji aktivnosti američkih diplomata koji su, bilo izravno, bilo neizravno, pokušavali privoljeti službeni Vatikan da reagira i obuzda djelovanje biskupa Perića koji je etiketiran kao hrvatski nacionalist, te kao takav i prepreka provedbi njihovih političkih interesa na prostoru BiH. Ova delikatna diplomatska aktivnost imala je za cilj politički pasivizirati biskupa Perića, sve do pokušaja njegovog eventualnog uklanjanja s biskupske službe u Hercegovini. Iako je u ovu diplomatsku akciju uloženo dosta truda, zahvaljujući dosljednom odnosu vatikanske administracije, pa i samih papa – Ivana Pavla II. i Benedikta XVI. – nije se uspjelo u njezinoj krajnjoj namjeri, te je biskup Perić unatoč ovim, a i mnogim drugim pokušajima diskreditacije ostao na svojoj službi sve do umirovljenja 2020. godine.
Teološki pogled izabranih crkvenih dokumenata na medijsku etiku
Authors: Zupčić Šime , Labaš Danijel
Published: November 2024

Ovim radom donosimo sustavni analitički presjek teološke medijske etike izložene u dokumentima Katoličke Crkve koji su posvećeni medijskoj tematici, od suvremenih dokumenata do Mirari vos iz prve polovice XIX. stoljeća. U širokom kontekstu mnogobrojnih etičkih pitanja koja se povezuju kako s tradicionalnim, tako i s novim medijima i njihovom deontologijom, i Katolička Crkva u svojim dokumentima posvećenima komunikaciji i medijima iznosi svoj pogled na medijsku etiku, služeći se svojim teološkim moralnim naučavanjem. Iz perspektive teološkog razmišljanja o moralnosti i etičnosti medija, jasan je stav da se medije same po sebi ne može smatrati etički dobrima ili etički lošima, već ih etički prihvatljivima ili neprihvatljivima čini sama upotreba medija, a etičku vrijednost daju svi sudionici medijskog procesa: od vlasnika preko urednika i novinara pa do korisnika medija. Cilj je ovoga rada analizirati i sustavno prikazati teološka etička stajališta i načela iznesena i obrazložena u izabranim crkvenim dokumentima koji se bave medijskom tematikom.
The generalized equity and exact credibility premiums with examples
Authors: Djebar Ahlem , Zeghdoudi Halim , Vinoth Raman
Published: November 2024

We investigate a more generalized alternative to the conventional credibility premium that results from squared-error loss, namely, equitable credibility premium (Promislow and Young, 1999), based on exponential family, and we derive an accurate credibility for Bühlmann model with an example. We provide sufficient conditions for accurate credibility and expand a generalised formula for the credibility weight in specific circumstances. In this article, we expand upon the research conducted by Promislow and Young (2000) to include situations where an actuary is provided with data regarding a policyholder who has a more extensive exponential family. In the first section, we established our notation and reformulation of exact credibility for a Bühmann model. We derive the class of general equitable credibility premiums in the second section.
Toxicological evaluation of Carthamus lanatus L (Carthame laineux) hydro-alcoholic extract in Wistar rats: acute oral toxic effects
Authors: Akram Melakhessou Mohamed , Eddine Marref Salah , Imene Becheker
Published: November 2024

Background: Despite the well-known phytotherapeutic properties of Carthamus lanatus L in traditional medicine, there is little evidence on its toxicity profile in hematological and biochemical parameters. Objective: This study was intended to evaluate the acute toxicity effect of Carthamus lanatus L. Methods: The toxicological impact of a hydroalcholic extract of Carthamus lanatus (HAECL) at 200, 400, and 800 mg/kg body weight on hematological indices in rats was assessed gradually at 24 hours after 1, 10, and 14 days. Results: We observed no significant difference in the consumption of food, body weight, or relative organ weights. Hematological and biochemical parameters revealed the non-adverse effects of prolonged oral consumption of Carthamus lanatus except for a slight increase but no significant increase in ASAT and ALAT and a no significant decrease in the percentage of basophils. Conclusions: These data imply that the extract has a non-hematotoxic potential. Overall, the impact of carthamus lanatus extract in this study shows that it is unlikely to be hematotoxic and might be a promising candidate in the treatment of coronary heart disease if taken at the levels tested.
The Prickly Pear, a shrub of real contribution to the livelihoods of farmers in in eastern dray land of Algeria
Authors: Douh Mourad , Karkour Larbi , Chekchaki Samir , Rebai Nouari , Samia Rebiai , Chacha Faicel , Bouchaala Laid
Published: November 2024

The study aims to assess the economic benefits and poverty impact of prickly pear fruit sales, focusing on commercial practices and the socio-economic status of participants. Data was gathered from 60 individuals across 32 locations through face-to-face surveys conducted from June to September 2023. The analysis, covering 20% of the regional actors, revealed that most participants were relatively young, with higher primary education levels and low university education (8.33%). Women involved were mostly divorced, and the majority of sellers were private farm owners, with others being forwarders and traders. Unemployment drove their engagement in this activity. The average income from prickly pear sales is 89.103 DZD, with net earnings of 60,000.00 DZD per trader, which increases with hours worked. Approximately 60 traders generate a total seasonal income of around 42,000.00 DZD, significantly benefiting local economies. Prickly pear trading offers crucial support to households, particularly during tough economic times, showcases its importance despite modest returns. The prickly pear trade in the region plays a vital role in supporting local households economically, especially during periods of financial instability. The trade offers both a source of income and an opportunity for independence, despite challenges associated with harvesting and market dynamics. The study concludes that prickly pear sales provide a sustainable income source with potential for growth, suggesting broader use of these crops for food, fodder, and energy in Algeria.
SNP alleviates ferric and salt stress in Phaseolus vulgaris seeds
Authors: Rodrigues Filho Josinei , Perin Idalina Tereza de Almeida Leite , Corte Viviana Borges , Pires Marina Reis
Published: November 2024

Seed germination and early development are delicate events often influenced by various environmental factors. Among these factors, the accumulation of salts and heavy metals in the soil is noteworthy. This study aimed to observe the effect of priming with solutions of sodium nitroprusside, polyethylene glycol 6000, and potassium nitrate on the germination of Phaseolus vulgaris seeds exposed to toxic conditions of iron and sodium chloride. Seeds were germinated on plates placed in a growth chamber at a constant temperature of 25°C and a 12-hour photoperiod. The percentage of germination, germination speed, root and shoot lengths, catalase, peroxidase activities, and malondialdehyde content were evaluated. Exposure to high concentrations of sodium chloride and iron reduced germination percentage, germination speed, root and shoot lengths of treated plants. Only sodium nitroprusside treatment mitigated the effects of stressors. No increase in malondialdehyde content was observed in any treatment, suggesting no lipid peroxidation of membranes. However, all treatments showed increased catalase activity, possibly indicating oxidative stress and metabolic damage. Sodium nitroprusside stands out as a stress alleviator for sodium chloride and iron accumulation during the germination phase.
Aplicação da Inteligência Artificial no diagnóstico de falhas de máquinas
Authors: Santos Neri Sandro Pereira dos , Silva Leandro Cardoso , Cardoso Edgard Gonçalves
Published: November 2024

Este estudo investigou a aplicação da inteligência artificial (IA) no diagnóstico de falhas em máquinas industriais, visando melhorar a eficiência operacional e reduzir os custos de manutenção. Por meio de uma revisão da literatura, e análise de dados operacionais, foram identificadas diversas alternativas para a aplicação de sistemas de IA, incluindo o uso de algoritmos de aprendizado profundo e técnicas de processamento de linguagem natural. Concluiu-se que a IA oferece um grande potencial para aprimorar a detecção precoce de falhas e a tomada de decisões proativas de manutenção. Recomenda-se que as empresas invistam em pesquisa e desenvolvimento, promovam a capacitação dos profissionais e estabeleçam parcerias estratégicas para colaborar na aplicação bem-sucedida de soluções baseadas em IA.
Atendimento a paciente pediátrico com quadro agudo de meningite por tuberculose: um estudo de caso
Authors: Andrade Beatriz Bentes de , Gomes Caio Luiz Marques , Andrade Gabrielle Bentes de , Jardim Tyane de Almeida Pinto
Published: November 2024

Introdução: A neurotuberculose é um tipo de tuberculose que invade o sistema nervoso central, considerada uma grave infecção causada pelo Mycobacterium tuberculosis. Objetivo: Realizar estudo de caso de um paciente pediátrico com quadro agudo de meningite por tuberculose. Metodologia: Estudo retrospectivo, descritivo, tipo relato de caso, construído a partir da análise do prontuário eletrônico do paciente. Estudo de caso: Paciente do gênero feminino, com idade de 4 anos e 11 meses, natural e procedente de Manaus, Amazonas, deu entrada em consultório de pronto socorro pediátrico em colo materno, mãe informou a ocorrência de dois episódios de queda de própria altura e hipotonia, seguidos de êmese com restos alimentares, sem outros sinais e sintomas associados. Foram realizados exame físico, exames laboratoriais e internação da paciente que permaneceu em monitorização contínua para investigação diagnóstica e tratamento do quadro.  Conclusão: A tuberculose do sistema nervoso central (SNC), devido sua alta morbimortalidade, é uma das formas mais temidas na infância, sendo necessário manter vigilância e saber que o conhecimento e a compreensão dos protocolos e estratégias de atendimento em emergências pediátricas pode ser o diferencial em todas as circunstâncias adversas durante a assistência.
Abordagem multidisciplinar tardia de elemento dental fraturado por trauma: relato de caso
Authors: Gonçalves Maria Clara de Almeida , Barbosa Jhullyana Shirley Pinheiro , Oliveira Adriana Pachêco de , Macedo Júlia Peixoto Campos de , Monteiro Naianne Ramos
Published: November 2024

Relatar uma abordagem multidisciplinar referente ao manejo de um dente escurecido. Paciente, sexo masculino, 17 anos, compareceu a clínica escola de odontológia queixando-se de um dente que havia escurecido após uma queda há 4 anos atrás. No exame clínico intra-bucal e radiográfico (periapical) constatou-se que o elemento 21 apresentava fratura coronária envolvendo esmalte e dentina (classe IV), além de rarefação óssea apical difusa e uma coloração acinzentada. O elemento encontrava-se assintomático e apresentou teste de sensibilidade pulpar com gás refrigerante negativo, firmando-se o diagnóstico de periodontite apical crônica. O tratamento proposto foi a necropulpectomia e, em seguida, a reabilitação estética e funcional do dente. Após a finalização do tratamento endodôntico, visando a obtenção de um melhor resultado estético, optou-se pela execução de duas sessões de clareamento dental interno e externo (peróxido de hidrogênio a 35%), executando-se a técnica imediata com selamento biomecânico. Diante do resultado obtido, a coloração do elemento dental não foi satisfatório e confeccionou-se uma faceta em resina composta, obtendo-se assim, uma estética favorável. O correto diagnóstico, planejamento e execução do tratamento é fundamental para devolver a saúde bucal e reduzir os danos relacionados à autoestima, oferecendo o suporte necessário ao paciente vítima de trauma dental.
Intervenções fisioterapêuticas na redução da dor crônica após o cancêr de mama
Authors: Silva Antonia Heide de Souza , Viana Larissa Martins , Oliveira Gilberlandio Roseno , Cruz Junior Epaminondas Rodrigues da , Oliveira Stella Jorge de , Ramos Fabiana Castro , Passos Xisto Sena , Morais Fernanda Dorneles de
Published: November 2024

Objetivo-. Identificar as melhores e mais utilizadas intervenções fisioterapêuticas para a redução da dor crônica em mulheres sobreviventes do câncer de mama. Métodos- Trata-se de uma revisão de literatura, segundo o método PRISMA. Para a busca da literatura, foram utilizadas as bases de dados BVS, SciELO e PubMed, resultando em 10 artigos originais publicados a partir de 2019, os quais apresentavam as intervenções fisioterapêuticas, para a redução da dor crônica após o câncer de mama, escritos em português e inglês. Resultados- Foram identificadas várias intervenções para a redução da dor crônica em mulheres  câncer de mama nas quais, a maioria dos estudos obtiveram resultados satisfatórios e mostraram a eficácia de terapias como o TENS, TEAS, Cinesioterapia, Yoga, Radiofrequência, Drenagem Linfática Manual, Massagem, Corrente Interferencial e Acupuntura. Conclusão- As principais intervenções fisioterapêuticas para reduzir a dor crônica em pacientes oncológicos foram TENS, TEAS e Cinesioterapia, sendo que esta mostrando-se mais eficaz, apresentando desfechos favoráveis em todos os artigos analisados. Algumas terapias, como acupuntura e TEAS, não alcançaram os efeitos esperados, possivelmente devido à falta de estudos específicos.
A importância dos exames de imagem no diagnóstico, prognóstico e planejamento de implantes: revisão de literatura
Authors: Carneiro Beatriz Siqueira , Monteiro Letícia Oliveira , Martinho Roberto Luiz de Menezes , Martinho Paulo Victor de Araújo
Published: November 2024

Introdução: A partir da descoberta dos raios x em 1895, por William Conrad Roentgen, o exame de imagem médico passou a ser proporcionado com maior acessibilidade e rapidez, para a odontologia, os exames de imagem oferecem o máximo de informações da região a ser analisada sendo assim um significativo recurso auxiliar de diagnóstico. Objetivo: ressaltar a utilidade e a importância dos exames radiográficos na tomada de decisões a respeito do planejamento de cada caso, visando a segurança do paciente e sucesso do procedimento. Metodologia: Foram realizadas revisões de literatura com as seguintes bases de dados: (SCIELO), Medical Literature Analysis and Retrieval System online (MEDLINE), Google acadêmico, Portal regional da BVS (BVS). Resultados: Com base na metodologia de pesquisa, foram selecionados 36 artigos publicados entre os anos de 2004 a 2024, abordando as temáticas na descoberta dos raios x, exames de imagem utilizados na odontologia, vantagens e desvantagens. Conclusão: o presente estudo proporcionou uma análise positiva através das revisões de literatura realizadas, diante dos parâmetros em relação a radiografia panorâmica e tomografia computadorizada de feixe cônico apresentadas, a tomografia computadorizada de feixe cônico é o exame de escolha para um diagnóstico preciso e planejamento seguro na implantodontia.
Efeitos vasomotores do vírus da dengue em pediatria: um relato de caso
Authors: Lima Thuane Teixeira , Oliveira Juliana Rebouças de
Published: November 2024

Introdução: Dengue é uma das doenças virais mais prevalentes em todo o mundo, representando um desafio significativo para a saúde pública, especialmente em regiões tropicais. Objetivos: realizar uma revisão sistemática da literatura dos últimos 10 anos, analisar criticamente a evidência disponível sobre esse tema e relatar um caso ocorrido em unidade pediátrica. Métodos: foram utilizados os bancos de dados: Pubmed, Google Scholar e Medline, selecionados 9 artigos pertinentes, que foram submetidos a uma análise detalhada, para embasar a redação do artigo, em concomitância, foi realizado um relato de um caso, acompanhado em hospital universitário, de uma criança que apresentou um fenômeno vasomotor pós infecção com o vírus da Dengue, para tal estudo foi aplicado o termo de consentimento livre e esclarecido(TCLE), para a responsável da criança e realizada a revisão em prontuário. Resultados: destacaram a importância de uma abordagem diferenciada em crianças devido à variabilidade na apresentação clínica da doença e ressaltaram a influência de fatores imunológicos e fisiológicos na resposta do organismo à infecção pelo vírus da dengue, no relato do caso analisado a investigação progrediu para descobrir o motivo dos fenômenos vasomotores em questão, sendo esgotadas as possibilidades diagnósticas mais comum de cianoses, foi aventado o fenômeno vasomotor pós dengue, com boa evolução no desfecho. Discussão: enfatizou a necessidade de pesquisas adicionais para preencher lacunas na literatura e aprimorar o manejo da doença em pacientes pediátricos, para a prática clínica destaca-se a importância de uma compreensão abrangente dos efeitos vasomotores da dengue em crianças para melhorar os desfechos clínicos e reduzir a carga da doença, sendo necessário uma investigação abrangente que afaste outras causas. Considerações Finais: frente a elevada prevalência do tema destaca-se a importância das vacinas na prevenção da dengue em crianças, ressaltando os avanços significativos na pesquisa de vacinas nos últimos anos. A inclusão de vacinas na estratégia de controle da dengue pode oferecer uma abordagem complementar e preventiva, reforçando ainda mais a importância da pesquisa contínua nessa área e da colaboração entre pesquisadores, profissionais de saúde e formuladores de políticas públicas.
Exploring the Incidence and Determinants of Surgical Site Infections in Caesarean Sections: A Five-Year Study
Authors: Bondili Nirupama Padmaja , Ravula Pallavi Chandra , Devi Sapam Anju , Gurrampally Sadguna
Published: November 2024

Background: Surgical site infection (SSI) is one of the most common complications following a cesarean section and has an incidence of 0.63 to 9.85%. It places physical, emotional and financial burden on the mother herself and on the health care system.
Aims and Objectives: The study aimed to identify and analyze the risk factors associated with SSIs in women undergoing both elective and emergency cesarean sections and to assess the risk factors and propose modifications to preoperative, intraoperative and postoperative practices to reduce the incidence of SSI. Optimization of maternal comorbidities, appropriate antibiotic prophylaxis, and evidence-based surgical techniques are some of the practices proven to be effective in reducing the incidence of SSI.
Theory of Space Quantization and the Quantum Level Understanding of the True Logics of the Principles of Thermodynamics and Heat Engines
Authors: Bhattacharya C
Published: November 2024

The recently discovered Topological Theory of Quantum Gravity (TTQG) is basically a Theory of Space Quantization (TSQ) and in this article first of all it has been substantiated that though the laws of thermodynamics, the well-known thermodynamic principles, the operations of heat engines are very much intuitive but they, in their conventional representations, miserably lack the harmony to the quantized ‘space -time’ of the universe. The well-known thermodynamic parameters, e.g., pressure (P), volume (V), heat content (H), internal energy (U), entropy (S), Gibbs free energy (G),....etc. and the related physical variables like ‘time’ (t)and ‘mass’ (m) do exist in the form of ‘quantum’ or ‘packets’(referred as Gravitons in TTQG) and those are continuously being exchanged between the so called ‘thermodynamic systems’ and the ‘space-time’. It has been shown in this article that a ‘thermodynamic system’ and the above said ‘space quantums’ are very much complimentary and ‘part and parcel’ to each other and a quantum level ‘space-time’ rich understanding has been made through the TSQ of the true logic behind the standing of the thermodynamic laws and the operations of the heat engines.
ЭФФЕКТИВНОСТЬ РАЗЛИЧНЫХ ТЕХНОЛОГИЙ ХРАНЕНИЯ ПЛОДОВ ГОЛУБИКИ
Authors: В.А. Гудковский , Л.В. Кожина , Ю.Б. Назаров , А.В. Сутормина
Published: November 2024

Технологии хранения в разной степени ингибируют созревание и развитие серой гнили плодов голубики, обеспечивают разные сроки эффективного хранения продукции. В условиях ОА они не превышают 10–14 суток, в условиях МА — 30 суток, в РА — 60 суток и более. Условия РА (t=0,5–1о С, СО2=10–12 %, О2=4–5 %) обеспечивают максимально высокий уровень сохранения качества (сохранение гармоничного вкуса продукции за счет сбалансированного содержания сухих растворимых веществ и титруемых кислот, сохранение структуры плодов, устойчивости к гнили).

Storage technologies differently inhibit the ripening and development of gray mold of blueberries and provide different periods of effective storage of production. Effective storage period does not exceed 10–14 days in RA conditions, 30 days — in MA conditions, 60 days or more — in CA conditions. Storage conditions of CA (t=0.5–1°С, CO2=10–12 %, O2=4–5 %) ensure the highest level of quality preservation (preservation of the harmonious taste of production due to the balanced content of dry soluble substances and titratable acids, preservation of the fruit structure, resistance to mold).