bluuebunny/crossref_metadata_2025 huggingface dataset:
Cosmic-Ray-driven Outflows from the Large Magellanic Cloud: Contributions to the LMC Filament
Authors: Bustard Chad , Zweibel Ellen G. , D’Onghia Elena , Gallagher III J. S. , Farber Ryan
Published: April 2020

In this paper, we build from previous work and present simulations of recent (within the past Gyr), magnetized, cosmic-ray driven outflows from the Large Magellanic Cloud (LMC), including our first attempts to explicitly use the derived star formation history of the LMC to seed outflow generation. We run a parameter set of simulations for different LMC gas masses and cosmic-ray transport treatments, and we make preliminary comparisons to published outflow flux estimates, neutral and ionized hydrogen observations, and Faraday rotation measure maps. We additionally report on the gas mass that becomes unbound from the LMC disk and swept by ram pressure into the Trailing Magellanic Stream. We find that, even for our largest outburst, the mass contribution to the Stream is still quite small, as much of the outflow-turned-halo gas is shielded on the LMCs far-side due to the LMCs primarily face-on infall through the Milky Way halo over the past Gyr. On the LMC’s near-side, past outflows have fought an uphill battle against ram pressure, with the near-side halo mass being at least a factor of a few smaller than that of the far-side. Absorption-line studies probing only the LMC foreground, then, may be severely underestimating the total mass of the LMC halo formed by outflows.
Estimation of the Physical Parameters of a CME at High Coronal Heights Using Low-frequency Radio Observations
Authors: Mondal Surajit , Oberoi Divya , Vourlidas Angelos
Published: April 2020

Measuring the physical parameters of coronal mass ejections (CMEs), particularly their entrained magnetic field, is crucial for understanding their physics and for assessing their geoeffectiveness. At the moment, only remote sensing techniques can probe these quantities in the corona, the region where CMEs form and acquire their defining characteristics. Radio observations offer the most direct means for estimating the magnetic field when gyrosynchrotron emission is detected. In this work we measure various CME plasma parameters, including its magnetic field, by modeling the gyrosynchrotron emission from a CME. The dense spectral coverage over a wide frequency range provided by the Murchison Widefield Array (MWA) affords a much better spectral sampling than possible before. The MWA images also provide a much higher imaging dynamic range, enabling us to image these weak emissions. Hence we are able to detect radio emission from a CME at larger distances (∼4.73 R
⊙) than have been reported before. The flux densities reported here are among the lowest measured in similar works. Our ability to make extensive measurements on a slow and otherwise unremarkable CME suggests that with the availability of data from the new-generation instruments like the MWA, it should now be possible to make routine, direct detections of radio counterparts of CMEs.
A new species of hagfish, Eptatretus wandoensis sp. nov. (Agnatha, Myxinidae), from the southwestern Sea of Korea
Authors: Song Young Sun , Kim Jin-Koo
Published: April 2020

Four specimens of the five-gilled white mid-dorsal line hagfish, Eptatretus wandoensissp. nov. were recently collected from the southwestern Sea of Korea (Wando). This new species has five pairs of gill apertures, 14–18 prebranchial slime pores, 4 branchial slime pores, a dark brown back with a white mid-dorsal line and a white belly. These hagfish are similar to Eptatretus burgeri and Eptatretus minor in having a white mid-dorsal line, but can be readily distinguished by the numbers of gill apertures (5 vs. 6–7), gill pouches (5 vs. 6), and prebranchial slime pores (14–18 vs. > 18), as well as the body color (dark brown back vs. gray or brown pale). In terms of genetic differences, Eptatretus wandoensis could be clearly distinguished from E. burgeri (0.9% in 16S rRNA and 8.5% in cytochrome c oxidase subunit I sequences) and E. minor (4.5% and 13.9%).
TLR2 2029C/T and TLR3 1377C/T and −7C/A Polymorphisms Are Associated with the Occurrence of Abdominal Aortic Aneurysm
Authors: Jabłońska Agnieszka , Zagrapan Branislav , Neumayer Christoph , Klinger Markus , Eilenberg Wolf , Nanobachvili Josif , Paradowska Edyta , Brostjan Christine , Huk Ihor
Published: April 2020

TLRs are a family of signaling sensors that play a crucial role in the host immune response and are involved in the modulation of inflammatory processes. To study their contribution to abdominal aortic aneurysm (AAA) formation and development, we determined the frequency of TLR2, TLR3, TLR4, and TLR9 single-nucleotide polymorphisms (SNPs) and investigated the association between polymorphisms and the risk of AAA incidence. A total of 104 patients with AAAs and 112 healthy, unrelated volunteers were screened for the presence of TLR2 (2029C/T and 2258G/A), TLR3 (1377C/T, 1234C/T, and −7C/A), TLR4 (896A/G, 1196C/T, and 3266G/A), and TLR9 (−1237T/C, −1486T/C, 1174G/A, and 2848C/T) SNPs by using PCR-RFLP analysis. The heterozygous genotype of the TLR2 2029C/T SNP was more common in patients with AAA than in healthy subjects (p < 0.0001) and was associated with at least an 8-fold increased risk of AAA incidence (p < 0.001). The wild-type genotype of the TLR3 −7C/A SNP was associated with a 3-fold increased risk of hypertension (p = 0.026). The heterozygous TLR3 genotype 1377C/T and −7C/A SNPs were less common in patients with AAA than in healthy subjects (p < 0.0001 and p = 0.0004, respectively) and were associated with a decreased risk of AAA occurrence (p < 0.001 and p = 0.0012, respectively). No relation to AAA risk was found for TLR4 SNPs. Heterozygous genotypes of the TLR2 2029C/T and TLR3 1377C/T and −7C/A SNPs may serve as genetic biomarkers of AAA incidence.
STING Sensing of Murine Cytomegalovirus Alters the Tumor Microenvironment to Promote Antitumor Immunity
Authors: Wilski Nicole A. , Stotesbury Colby , Del Casale Christina , Montoya Brian , Wong Eric , Sigal Luis J. , Snyder Christopher M.
Published: April 2020

CMV has been proposed to play a role in cancer progression and invasiveness. However, CMV has been increasingly studied as a cancer vaccine vector, and multiple groups, including ours, have reported that the virus can drive antitumor immunity in certain models. Our previous work revealed that intratumoral injections of wild-type murine CMV (MCMV) into B16-F0 melanomas caused tumor growth delay in part by using a viral chemokine to recruit macrophages that were subsequently infected. We now show that MCMV acts as a STING agonist in the tumor. MCMV infection of tumors in STING-deficient mice resulted in normal recruitment of macrophages to the tumor, but poor recruitment of CD8+ T cells, reduced production of inflammatory cytokines and chemokines, and no delay in tumor growth. In vitro, expression of type I IFN was dependent on both STING and the type I IFNR. Moreover, type I IFN alone was sufficient to induce cytokine and chemokine production by macrophages and B16 tumor cells, suggesting that the major role for STING activation was to produce type I IFN. Critically, viral infection of wild-type macrophages alone was sufficient to restore tumor growth delay in STING-deficient animals. Overall, these data show that MCMV infection and sensing in tumor-associated macrophages through STING signaling is sufficient to promote antitumor immune responses in the B16-F0 melanoma model.
NKG2Cpos NK Cells Regulate the Expansion of Cytomegalovirus-Specific CD8 T Cells
Authors: Grutza Ralf , Moskorz Wiebke , Senff Tina , Bäcker Eugen , Lindemann Monika , Zimmermann Albert , Uhrberg Markus , Lang Philipp A. , Timm Jörg , Cosmovici Christine
Published: April 2020

Infection with the human CMV associates with phenotypic alterations in lymphocyte subsets. A highly reproducible finding in CMV-seropositive individuals is an expansion of NKG2Cpos NK cells. In this study, we analyzed if the altered NK cell compartment in CMV-seropositive human donors may affect CMV-specific CD8 T cells. Resting CMV-specific CD8 T cells were terminally differentiated and expressed high levels of the NKG2C ligand HLA-E. Activation of CMV-specific CD8 T cells with the cognate Ag further increased HLA-E expression. In line with a negative regulatory effect of NKG2Cpos NK cells on HLA-Ehigh CD8 T cells, depletion of NKG2Cpos NK cells enhanced Ag-specific expansion of CMV-specific CD8 T cells in vitro. In turn, the activation of NK cells in coculture with CMV-specific CD8 T cells promoted a selective loss of HLA-Ehigh CD8 T cells. To test if NKG2Cpos NK cells can target HLA-Ehigh CD8 T cells, Jurkat T cells with and without stabilized HLA-E on the surface were used. NKG2Cpos NK cells stimulated with HLA-Ehigh Jurkat cells released higher levels of Granzyme B compared with NKG2Cneg NK cells and NKG2Cpos NK cells stimulated with HLA-Elow Jurkat cells. Moreover, intracellular levels of caspase 3/7 were increased in HLA-Ehigh Jurkat cells compared with HLA-Elow Jurkat cells, consistent with higher rates of apoptosis in HLA-Ehigh T cells in the presence of NKG2Cpos NK cells. Our data show that NKG2Cpos NK cells interact with HLA-Ehigh CD8 T cells, which may negatively regulate the expansion of CMV-specific CD8 T cells upon activation.
Simulation-based education program on postpartum hemorrhage for nursing students
Authors: Kim Miok , Ha Juyoung
Published: April 2020

Purpose: This study was conducted to develop a simulation-based postpartum care education program for women with postpartum hemorrhage and to verify the effects of the program on postpartum care. Methods: This program was developed according to the ADDIE model of instructional system design, which consists of analysis, design, development, implementation, and evaluation phases. This quasi-experimental study used a non-equivalent control group pre- and post-test design, and data were collected from April 23 to May 4, 2015. To verify the effects of the program, 33 nursing students in the experimental group participated in a simulation program, whereas 31 students in the control group were given a case study. Results: The experimental group had statistically significantly higher scores for clinical performance (t=–4.80, p<.001), clinical judgment (t=–4.14, p<.001), and learning satisfaction (t=–10.45, p<.001) than the control group. Conclusion: The results of this study indicate that the simulation-based postpartum care education program for women with postpartum hemorrhage was effective for developing students’ competency, implying that this program should be integrated into the clinical training component of the maternal nursing curriculum.
Factors influencing infertility-related quality of life in infertile women
Authors: Kim Yun Mi , Nho Ju-Hee
Published: April 2020

Purpose: The rate of infertility in South Korea is steadily increasing. Infertile women experience various physical, psychological, and relational problems that affect their infertility–related quality of life (QoL). This study investigated infertile women’s infertility-related QoL with the goal of identifying how it is influenced by fatigue, depression, and marital intimacy.Methods: A sample of 140 infertile women was surveyed in a cross-sectional study. Data were collected from February to April 2018 using self-report structured questionnaires at three infertility clinics located in Jeonju, Korea. Data were analyzed using the independent t-test, analysis of variance, Pearson correlation coefficients, and stepwise multiple regression analysis in SPSS for Windows version 25.0. The subjects agreed to complete a face-to-face interview, including administration of the Fatigue Severity Scale, Depression Anxiety Stress Scale-21, Marital Intimacy Scale, and the Fertility Quality of Life tool.Results: The mean age of the participants was 35.6±4.3 years. Infertility-related QoL was negatively correlated with fatigue (r=–.42, p<.001) and depression (r=–.56, p<.001), and positively correlated with marital intimacy (r=.30, p<.001). Multiple regression analysis showed that depression (β=–0.44, p<.001), fatigue (β=–0.27, p<.001), and husband’s attitude (β=–0.19, p=.007) had significant effects on the QoL of infertile women, accounting for 40.5% of the variance in infertility-related QoL. Conclusion: The study provides insights into how infertile women’s infertility-related QoL was influenced by depression, fatigue, and their husbands’ attitudes regarding infertility treatment. To improve infertile women’s infertility-related QoL, healthcare providers should consider developing strategies to decrease depression and fatigue in infertile women and to address their husbands’ attitudes.
Effects of stress, depression, and spousal and familial support on maternal identity in pregnant women
Authors: Seo Hye-Jung , Song Ju-Eun , Lee Youngjin , Ahn Jeong-Ah
Published: April 2020

Purpose: The objective of this study was to identify the factors influencing maternal identity in pregnant women. Methods: Using a descriptive research design, a cross-sectional survey was conducted. In total, 127 pregnant women were recruited from a tertiary hospital in Korea from January to April 2019. Measurements included maternal identity, stress, depression, spousal and familial support, and demographic and obstetric characteristics. Data were analyzed by descriptive statistics, the independent t-test, one-way ANOVA, Pearson correlation coefficients, and stepwise multiple regression using SPSS version 25.0. Results: The mean score for maternal identity was 131.15 out of 160, and the mean scores for stress, depression, and spousal and familial support were 14.59 (out of 40), 6.82 (out of 30), and 109.04 (out of 132), respectively. Stress (r=–.38, p<.001), depression (r=–.37, p<.001), and spousal and familial support (r=.37, p<.001) were significantly correlated with maternal identity. In multiple regression analysis, stress (β=–0.27, p=.005) and spousal and familial support (β=0.23, p=.014) were found to be significant factors influencing maternal identity in pregnant women (F=14.17, p<.001). Conclusion: It is necessary to develop effective strategies to mitigate stress and to encourage spousal and familial support in pregnant women. Such strategies could further enable pregnant women to enhance their maternal identity.
Unmet healthcare needs and related factors according to gender differences in single-person households
Authors: Chae Hyun Ju , Kim Mijong
Published: April 2020

Purpose: This study was conducted to identify unmet healthcare needs among male and female one-person households and to explore related factors by gender. Methods: Data were drawn from the 2017 Korea National Health and Nutrition Examination Survey. The final sample consisted of 820 one-person households. The statistical analysis, conducted in SPSS version 20.1, included complex sampling analysis; descriptive statistics, the chi-square test, and logistic regression. Results: The demographic and socioeconomic characteristics of women in one-person households were significantly different from those of men in one-person households. Women in single-person households were mainly in their 70s or older and married, and they tended to have a low education level, low income, and no formal occupation. Unmet healthcare needs were experienced by 17.3% of women in one-person households and 13.5% of men in one-person households, which was not a statistically significant difference (χ2=2.17, p=.139). Factors related to unmet healthcare needs were subjective health status and unmet dental care needs in single-person-household men. By contrast, having experienced impairment within the past year, stress, and unmet dental care needs were factors related to unmet healthcare needs in single-person-household women. Conclusion: As one-person households become increasingly common, more attention needs to be paid to them and our understanding of them needs to be improved. Women in one-person households, in particular, are especially vulnerable, as they experience more unmet healthcare needs.
Systematic drug repurposing to enable precision medicine: A case study in breast cancer
Authors: Taylor Krystyna , Das Sayoni , Pearson Matthew , Kozubek James , Strivens Mark , Gardner Steve
Published: April 2020

Background and Objectives:

Precision medicine and drug repurposing provide an opportunity to ameliorate the challenges of declining pharmaceutical R&D productivity, rising costs of new drugs, and poor patient response rates to existing medications. Multifactorial “disease signatures” provide unique insights into the architecture of complex disease populations that can be used to better stratify patient groups, aiding the delivery of precision medicine.

Methods:

Analysis of a complex disease (breast cancer) population was undertaken to identify the combinations of single-nucleotide polymorphisms that are associated with different disease subgroups. Target genes associated with the disease risk of these subgroups were examined, followed by identification and evaluation of existing active chemical leads as drug repurposing candidates.

Results:

One hundred and seventy-five disease-associated gene targets relevant to different subpopulations of breast cancer patients were identified. Twenty-three of these genes were prioritized as both promising novel drug targets and repurposing candidates. Two targets, P4HA2 and TGM2, have high repurposing potential and a strong mechanistic link to breast cancer.

Conclusions:

This study showed that detailed analysis of combinatorial genomic (and other) features can be used to accurately stratify patient populations and identify highly plausible drug repurposing candidates systematically across all disease-associated targets.
Gelfand Pairs Involving the Wreath Product of Finite Abelian Groups with Symmetric Groups
Authors: Tout Omar
Published: April 2020

It is well known that the pair $(\mathcal {S}_n,\mathcal {S}_{n-1})$ is a Gelfand pair where $\mathcal {S}_n$ is the symmetric group on n elements. In this paper, we prove that if G is a finite group then $(G\wr \mathcal {S}_n, G\wr \mathcal {S}_{n-1}),$ where $G\wr \mathcal {S}_n$ is the wreath product of G by $\mathcal {S}_n,$ is a Gelfand pair if and only if G is abelian.
Avaliação extrínseca mediante a interconsistência nos catálogos das bibliotecas universitárias da amazônia brasileira: UFPA, UFOPA, IFPA E UFRA
Authors: Sousa Letícia Lima de , Barros Thiago Henrique Bragato , Redigolo Franciele Marques , Fujita Mariângela Spotti Lopes
Published: April 2020

Objetivo: Analisar a consistência da indexação em catálogos online das BUs da Universidade do Estado do Pará (UEPA), Universidade Federal do Oeste do Pará (UFOPA), Universidade Federal do Pará (UFPA), Universidade Federal do Sul e Sudeste do Pará (UNIFESSPA), Instituto Federal do Pará (IFPA) e Universidade Federal Rural da Amazônia (UFRA).Metodologia: Mensurar o grau de consistência entre os registros utilizando a avaliação extrínseca mediante a interconsistência em catálogos online. Calculou-se o índice de consistência rígido e relaxado entre os registros por meio da equação de consistência adaptada por Gil Leiva (2008), a partir da fórmula de Hooper (1965), e readaptada no presente estudo para abranger uma amostra de 10 ensaios obtidos nos catálogos das 6 BUs analisadas.Resultado: O índice de consistência rígido é baixo em relação ao índice de consistência relaxado que apresentou valores maiores, pois o índice de consistência rígido apresenta um intervalo que varia 5,83 a 3,33. Já o índice de consistência relaxado apresentou maior variação com um intervalo de 33,5 a 19,5. Verifica-se que o índice de consistência rígido apresenta média de 24,8 e o índice de consistência relaxado tem média de 24,05%.Conclusões: A catalogação de assuntos apresenta em alguns momentos termos concordantes e divergentes nos catálogos online das BUs. A variação na atribuição dos termos entre os indexadores se deve a inexistência de política de indexação formalizada. Constata-se a validade da avaliação extrínseca mediante a interconsistência para verificação do grau de consistência dos registros.
Enriquecimento semântico para a disponibilização de dados abertos: teoria e prática
Authors: Torino Emanuelle , Trevisan Gustavo Lunardelli , Coneglian Caio Saraiva , Botega Leonardo Castro , Santarem Segundo José Eduardo , Vidotti Silvana Aparecida Borsetti Gregorio
Published: April 2020

Objetivo: Apresentar o processo de formalização necessário à disponibilização de dados abertos no contexto do linked open data, utilizando-se, neste caso, dados que estão no contexto da pesquisa científica.  Método: Para a elaboração do estudo, foram selecionados três datasets, dois disponíveis no portal Dados Abertos CAPES e o terceiro, consiste dos dados do Open Researcher and Contributor ID (ORCID). Como procedimentos metodológicos foram utilizados a pesquisa bibliográfica para embasamento teórico-conceitual do estudo e a pesquisa descritiva para explorar e fornecer informações quanto ao processo de enriquecimento de dados abertos.Resultado: Apresenta como resultado a descrição do processo necessário à disponibilização de um conjunto de dados enriquecido, a partir da modelagem e estruturação, pronto para a conversão ferramental e recuperação.Conclusões: A partir desse estudo, é possível visualizar como ocorre o processo de enriquecimento semântico de dados no contexto do linked open data, abarcando a seleção, análise, processamento e preparação visando a disponibilização, o uso e o reuso.
Análise de políticas esportivas: compartilhando uma proposta teórico-metodológica
Authors: Athayde Pedro Fernando Avalone , Carneiro Fernando Henrique Silva , Matias Wagner Barbosa , Mascarenhas Fernando
Published: April 2020

Este artigo de revisão apresenta uma proposta teórico-metodológico vinculada ao materialismo dialético para análise de políticas esportivas. Após revisão sistemática sobre a produção de conhecimento no tema da política pública na Educação Física, os autores apresentam os pressupostos teóricos que fundamentam sua proposta. Posteriormente, realizam descrição dos aspectos e indicadores do modelo de análise aplicados ao contexto da política esportiva. Por fim, destaca-se a impossibilidade de emprego universal e homogêneo do modelo, apontando para a necessidade de coteja-lo com o contexto histórico e social da realidade concreta observada, além das múltiplas determinações do objeto investigado.
Estudos acadêmicos sobre o remo: a Educação Física como campo de produção de conhecimento histórico
Authors: Farias Mário Machado , Ribeiro Sara Fantin , Silva Carolina Fernandes da
Published: April 2020

Este artigo tem como objetivo compreender como está configurada a produção do conhecimento sobre o remo no campo da Educação Física. Através da técnica Estado da Arte, realizou-se um levantamento das produções acadêmicas sobre o remo no período de 2000 a 2018, utilizando como palavras-chave remo e rowing. Foram encontrados 37 estudos. Para a análise, determinou-se as seguintes categorias: quantidade de estudos por ano, perspectiva (geral ou histórico-cultural), região, área de conhecimento e idioma. A área da Educação Física, dentre tantas outras áreas que poderiam fomentar e desenvolver estudos sobre o remo e sobre esporte em geral, concentra a maioria das produções. Ou seja, o remo, sobretudo no que diz respeito a sua compreensão, tornou-se um tema da tradição e da cultura dessa área de conhecimento chamada Educação Física. Tais dados indicam que os estudos históricos representam um produtivo subcampo de conhecimento da Educação Física.
Ginástica rítmica: experiência baseada nos esportes unificados da Special Olympics
Authors: Leite Elisete De Andrade , Rodrigues José Luiz , Leitão Maria Teresa , Lopes Keyla Ferrari , Carvalho Camila Lopes de
Published: April 2020

O programa de Esporte Unificado, da Special Olympics, possibilita práticas esportivas para pessoas com e sem deficiência intelectual conjuntamente, visando a promoção da inclusão social. Fundamentado neste programa, foi realizada uma pesquisa-ação objetivando analisar a relação entre atletas com e sem deficiência intelectual em aulas de ginástica rítmica fundamentadas no Esporte Unificado. Para isso, 18 meninas, 12 com deficiência intelectual e 6 sem essa condição, realizaram aulas de ginástica rítmica, conjuntamente, por 12 semanas, com 2 sessões semanais de 2 horas cada, em uma quadra de esportes de Guaratinguetá, São Paulo, Brasil. Ao final  do programa, foi empregada uma entrevista semiestruturada com as meninas sem deficiência, apreciando os dados por análise de conteúdo. Os resultados apontaram que a interação entre atletas com e sem deficiência promoveu melhoras na performance das atletas e possibilitou a construção de conhecimento sobre as diversidades, alcançando atitudes de aceitação e respeito pelas diferenças.
Independência catalã, identidade e globalização no Fútbol Club Barcelona
Authors: Oliveira Jonathan Rocha de , Capraro André Mendes
Published: April 2020

A Catalunha enfrenta uma histórica crise política e econômica, acentuada nos últimos anos. O futebol local tangenciou esses desdobramentos que afetaram a dinâmica estrutural e a identidade dos clubes na região, especialmente, o FC Barcelona. Tencionando as abordagens históricas, políticas e o dualismo entre o global e o local, este estudo visou analisar o impacto da identidade catalã, independentismo catalão e a globalização no FC Barcelona. Para tanto, utilizou-se referencial bibliográfico, fontes históricas documentais, reportagens. Concluiu-se que a identidade do Clube é reconstruída continuamente, de acordo com as ações e posições de seus distintos grupos diretivos em relação à situação política e econômica local. Todavia, as questões esportivas e financeiras são o fio condutor nas tomadas de decisão do clube atualmente, em detrimento de sua representatividade social na região.
Data Control and Surveillance in the Global TB Response: A Human Rights Analysis
Authors: Albrecht Kat , Citro Brian
Published: April 2020

The global response to the tuberculosis (TB) epidemic is generating copious amounts of personal health data. The emerging emphasis on the use of active case finding and digital adherence technologies in the TB response will increase the amount and expand the kind of data produced and used by public and private health officials. The production of personal data in high TB burden countries, in particular, must be considered in light of their colonial histories. In doing so, we argue that interventions to eliminate TB at global and national levels are ushering in a new era of data colonisation and surveillance in the name of public health. This, in turn, raises critical concerns for the human rights of people affected by TB, many of whom belong to vulnerable or marginalised groups. We examine the normative and legal content for a set of international human rights critical to the TB response, highlighting how each right implicates the production and use of personal health data. We also demonstrate that these rights are, by and large, enshrined in the constitutions of each high TB burden country. Finally, we use these rights to analyse active case finding and digital adherence technologies to pinpoint their unique data risks and the threats they pose to the human rights of people affected by TB.
Implicaciones didácticas del concepto biotecnología
Authors: Roa Acosta Robinson , González-Galli Leonardo , Valbuena Ussa Édgar Orlay
Published: April 2020

Este artículo hace una aproximación a la naturaleza, definiciones, circunstancias y significados del concepto biotecnología, y a sus implicaciones para la enseñanza. La aproximación al surgimiento de este concepto indica la pluralidad de significados y de disciplinas que abarca, así como su complejidad. Las conclusiones hacen evidente la importancia de su investigación en la didáctica de las ciencias y la relevancia de incluir en la formación inicial de profesores de ciencias naturales aspectos filosóficos, históricos y epistemológicos de la biotecnología.
Desarrollo de competencias para la orientación educativa en la formación inicial de profesores
Authors: Sunza-Chan Sandra Paola
Published: April 2020

Una de las áreas disciplinares y de práctica que configura el quehacer del educador es la orientación educativa. El objetivo de este trabajo es describir las condiciones metodológicas más relevantes para el desarrollo de competencias para la orientación educativa durante la formación inicial docente. Para tal efecto, se desarrolló una investigación cualitativa, de alcance descriptivo, con estudiantes y profesores de la Licenciatura en Educación de la Universidad Autónoma de Yucatán, México. El método es fenomenológico hermenéutico. Los resultados muestran la relevancia de los proyectos de práctica y el servicio social como ejes fundamentales del desarrollo de las competencias en orientación educativa.
Líneas teóricas fundamentales para una educación emocional
Authors: Barrios-Tao Hernando , Peña Rodríguez Lina Johanna
Published: April 2020

El objetivo del artículo es trazar líneas teóricas que puedan fundamentar procesos de educación emocional. El método se inscribe en la revisión narrativa, caracterizada por investigar un tópico de forma más o menos exhaustiva, y se ubica en el espectro amplio de la relación entre emociones y educación. Los resultados, presentados en forma narrativa, inician con la comprensión de la complejidad y multidimensionalidad de las experiencias emocionales, con base en la relación entre neurociencias, emociones y procesos educativos. La conclusión fundamental es la necesidad de una educación emocional que transite de la inteligencia y las competencias socioemocionales hacia una visión ampliada al desarrollo de las experiencias emocionales, con una visión de la educación extendida a lo largo de toda la vida y a la vida misma.
The Anglo-Saxon New Negro: Sutton E. Griggs’s Anglo-Saxonism and the Quest for Cultural Paternity in Imperium in Imperio (1899)
Authors: Tamplin William
Published: April 2020

Sutton Elbert Griggs (1872–1933) wrote the first major African-American political novel, Imperium in Imperio (1899). Imperium is a utopian novel and the first novel to represent the New Negro. This article argues that the novel’s protagonist, Belton Piedmont, is Griggs’s unflawed utopian exemplar of the New Negro, that Griggs draws on nineteenth-century Anglo-Saxonist discourse to construct his characters Belton and Bernard, and that Griggs employs a system of binaries that demands that the New Negro choose which kind of Anglo-Saxon to become. In Imperium Griggs shows that the Anglo-Saxon is the Negro’s cultural father and that by imitating the best qualities of the Anglo-Saxon, the Negro could be lifted up. Such imitation should not detract from Griggs’s black nationalist credentials. Griggs was a committed intellectual who attempted to use the master’s tools (Anglo-Saxonism) to restructure the master’s house (white supremacy) and build an annex (the Anglo-Saxon New Negro).
Segurança do paciente em serviços de saúde: uma análise na cidade de Salvador, Bahia
Authors: Magalhães Costa Eliana Auxiliadora , Lobão William Mendes , Ribas Camila Lapa Matos , Passos Nathália Muraiviechi
Published: April 2020

Objetivo: Avaliar a política nacional de segurança do paciente em hospitais de grande porte de Salvador. Método: Estudo de casos múltiplos em hospitais terciários. A coleta de dados ocorreu entre outubro de 2017 e outubro de 2018, com profissionais dos núcleos de segurança do paciente (NSP). Foram analisadas quatro variáveis independentes: constituição dos NSP; ações de planejamento do controle dos eventos adversos (EA); atividades técnico- -operacionais desenvolvidas pelos NSP; e ações de monitoramento dos EA no hospital. Resultados: Dos 20 NSP existentes, estudaram-se 12 (60%). Todos os hospitais possuem NSP constituídos, 91,7% têm plano de segurança do paciente, e 50% contam com profissional com dedicação exclusiva. Das instituições, 58,3% implementam todos os protocolos obrigatórios, sendo identificação do paciente (83,3%) e higienização das mãos (83,3%) os mais frequentes. Os percentuais de EA identificados foram: lesão por pressão (88,9%), queda do leito (77,8%) e erros de medicamentos (75,0%). Conclusão: Os EA aqui referidos sinalizam a necessidade de adequações em prol da segurança do paciente. Os NSP não atendem totalmente às políticas regulatórias vigentes no país, carecendo, portanto, de adequações e de controle sanitário efetivo.
Manual Drawing in Transformation: A Brief Assessment of “Design-by-Drawing” and Potentials of a Body Technique in Times of Digitalization
Authors: Hasenhütl Gert
Published: April 2020

This paper analyzes the transformation of manual drawing in the context of design and art. The historical paradigm shift from “unselfconscious form-making processes” to “design-by-drawing” is closely associated with the current transformation of manual drawing into “digital” or “spatial sketching.” It is argued that design-by-drawing has changed our view of manual drawing as a body technique, for example, from hand–eye coordination more toward an aesthetic perspective by coupling certain forms of attention to this technique. Design-by-drawing is transforming manual drawing into diagramming, coding, or modeling within the paradigm of system design. It becomes obvious that the paradigm shift is not based on disruptive but on incremental innovations since the 1960s. An important focus is on the disparity between a deskilling of classical manual abilities and a reskilling of “body techniques” by the use of innovative man–machine interfaces. By reviewing the pros and cons of manual drawings from the fields of engineering design, graphic design, and art education, future prospects of the use of manual drawings are shown. Examining historical changes in manual drawing can help in understanding current transformations. The arguments presented can contribute to the development of a new framework for the use of this classic technique in design.
Do Preconditions of Inflation Targeting Framework Matter?
Authors: Ali Meerza Syed Imran
Published: April 2020

The main feature of inflation targeting (IT) framework is the public announcement by the central bank that it will keep inflation at a numerical inflation target. A large literature addresses preconditions that a country should satisfy before adopting IT. However, there is much debate about whether satisfying these preconditions are essential. This study addresses this debate. Empirical results indicate that the fulfillment of preconditions before IT adoption ensures effective implementation of IT in the short-run. However, countries that met all preconditions before IT adoption do not have an advantage over countries that didn’t meet all preconditions before IT adoption in the long-run.
European Industries’ Energy Efficiency under Different Technological Regimes: The Role of CO2 Emissions, Climate, Path Dependence and Energy Mix
Authors: Stergiou Eirini , Kounetas Kostas
Published: April 2020

The assessment of industrial-level energy efficiency’s (EE) development is a critical research topic that has entrenched in the global battle against climate change. Under the Energy Efficiency Directives 2012/27/EU and 2018/2002/EU, European Commission sets specific industrial energy efficiency targets, rules and obligations for the 2020-2030 period aiming, among others, at specific energy intensity reduction and energy efficiency improvements. In this paper we use a balanced panel of fourteen European industries from twenty-seven countries for the period 1995-2011 under a metatechnology framework. The aim of this study is to evaluate, at a first stage, the industrial total factor energy efficiency (TFEE) at a national and European level by incorporating technological heterogeneity through a nonparametric approach. Reflecting the divergent views on the importance of desirable and undesirable outcomes in the pursuit of TFEE, we additionally estimate industrial performance by prioritizing either economic or environmental aspects. At the second stage of our analysis, econometric models are applied to investigate the main factors of industrial TFEE using sector specific and country characteristics while we further proceed with a ft and ^-convergence analysis for our TFEE measures. The results of this study reveal that small-scale economies exhibit persistent high TFEE scores. At the same time, TFEE determinants suggest that path dependence phenomena have a strong presence, climatic characteristics occur while energy mix displays both linear and non-linear relationship. Either considering one desirable output or consolidating the undesirable output in the production function our results indicate a strong evidence of conditional and unconditional convergence in TFEE scores.
Locational (In)Efficiency of Renewable Energy Feed-In Into the Electricity Grid: A Spatial Regression Analysis
Authors: Hofer Tim , Madlener Reinhard
Published: April 2020

This paper presents an econometric analysis of curtailment costs of renewable energy sources (RES) in Germany. The study aims at explaining and quantifying the regional variability of RES curtailment, which is a measure to relieve grid overstress by temporarily disconnecting RES from the electricity grid. We apply a Heckit sample selection model, which corrects bias from non-randomly selected samples. The selection equation estimates the probability of occurrence of RES curtailment in a region. The outcome equation corrects for cross-sectional dependence and quantifies the effect of RES on curtailment costs. The results show that wind energy systems connected to the distribution grid increase RES curtailment costs by 0.7% per MW (or 0.2% per GWh) in subregions that have experienced RES curtailment over the period 2015-2017. The implication of this finding is that policymakers should set price signals for renewables that consider the regional grid overstress, in order to mitigate the cost burden on consumers due to excess generation from RES.
Rapid Detection of Cytomegalovirus and Listeria monocytogenes Infection in Symptomatic Newborns by Fluorescence End-Point Detection PCR (FEP PCR)
Authors: Shahrokhi Nader , Seid Shakeri Talayeh , Shirvani Fariba , Seifi Kimia
Published: April 2020

Background: Congenital CMV infection is the most prevalent congenital infection in the world, and perinatal Listeria infection is an important cause of neonatal sepsis. The identification of these two infections is hard. The PCR technique is a sensitive method, which is not simply available in Iran. Objectives: This study investigated the prevalence of CMV and Listeria in 100 urine samples from under 21-day-old neonates with positive risk factors by PCR electrophoresis and fluorescent end-point detection (FEP) PCR in Tehran referral hospitals. Methods: We used 100 urine samples from neonates admitted to 11 medical centers in Tehran with positive selected clinical symptoms compatible with these infections. Electrophoresis and FEP PCR for CMV and Listeria were performed on all urine samples. For the data analysis, SPSS version 21 software was used, and p values of less than 0.05 were considered significant. Results: We collected 100 urine samples from 100 under 21-day-old neonates, referring to Tehran hospitals. Seven cases were positive for Listeria, and 58 cases were positive for CMV by electrophoresis and FEP PCR. Respiratory distress was the most common clinical finding in both groups. The Mc-Nemar test revealed a statistical agreement between calcification and CMV and meningitis and Listeria (P = 0.18 and 0.07, respectively). There was a positive relationship between the neonates’ age and CMV-positive condition (P = 0.001). This result was not significant among Listeria-positive cases. Conclusions: Screening for CMV and Listeria infections in neonates with clinical features compatible with these intrauterine infections may give important information for their treatment and follow-up.
Comparison of the Imaging and Pathological Features of Telangiectatic Osteosarcoma and Aneurysmal Bone Cyst of Long Tubular Bones
Authors: Shi Yun-Heng , Han Shu-Man , Sun Tao , Yu Bao-Hai , Wu Hui-Zhao , Wu Wen-Juan , Gao Bu-Lang
Published: April 2020

Background: The clinical, imaging and pathological features of telangiectatic osteosarcoma (TOS) in long bones are helpful for differentiation from aneurysmal bone cysts (ABC). Objectives: To investigate the clinical, imaging and pathological features of TOS in comparison with ABC in long bones. Patients and Methods: Seventeen patients with TOS and 17 patients with ABC in our hospital were analyzed in the clinical, imaging and pathological features for proper diagnosis. Results: For plain radiographs in 17 TOS cases, a soft tissue mass was detected in 14 cases, lytic bone destruction in 13, ill-defined border in 12, periosteal reaction in eight, formation of the Codman triangle in five, pathological fracture in three, and calcification in one. In 17 cases with ABC, an ill-defined border was found in fifteen cases, lytic and expansile destruction in eleven, thinned sclerotic rim in twelve, eccentrically location in ten, coarse septations in eight, a soft tissue mass in three, pathological fracture in three, periosteal reaction in two, and ill-defined border in two cases. In CT imaging of TOS, multiple cysts were in twelve cases, and fluid-fluid levels in three. In ABC, multiple cysts were in eleven cases while fluid-fluid levels in four. In MRI presentations of TOS, low and medium signal was present in the T1-weighted imaging (T1WI), whereas mixed (9/12) or high signal (3/12) was presented in the T2 WI with inhomogeneous signal. Four cases had multiple cysts and fluid-fluid levels in the bone destruction and soft tissues. The cysts had long T1 and long T2 signal with isointense signal in the septations (5/12). Fat inhibition sequence showed clear cystic changes. In ABC, low complete or incomplete signal was demonstrated in all lesions with a higher incidence of fluid-fluid levels (8/11). The lesion was of low and medium inhomogeneous signal in the T1 WI but mixed signal in T2 WI (6/11) including hyperintense signal in the upper part but mixed signal in the lower part in four cases or hyperintense signal (1/11) in T2 WI. The histopathological features of TOS were bleeding inside the lesion, highly atypia tumor cells of malignancy in the septa and tumorous bone tissue. The septa of ABC were composed of proliferative fibroblasts with dispersed polykaryocytes, reactive woven bone but no atypical cells. Conclusion: The clinical, imaging and pathological characteristics should be combined to make a correct differential diagnosis between telangiectatic osteosarcoma and aneurysmal bone cyst.
La información alimentaria en la Unión Europea en relación con aspectos éticos
Authors: Balaguer Pérez Amalia
Published: April 2020

Los alimentos, además de tener relación con la salud, tienen conexión con aspectos culturales, éticos y medioambientales. La importación y exportación de alimentos, las tecnologías, y el bienestar animal, entre otros, despiertan preocupaciones entre las personas consumidoras, que, para poder elegir con conocimiento, necesitan información al respecto.El presente artículo analiza aquellos aspectos que se han relacionado con preocupaciones éticas, regulados por la legislación de la Unión Europea referente a la información alimentaria, con el objetivo de alcanzar conclusiones sobre la regulación en este ámbito, sus limitaciones y las demandas existentes al respecto. En particular, se centra en el etiquetado, y analiza la normativa en varios ámbitos específicos: origen de los alimentos, alimentos vegetarianos y veganos, bienestar animal, alimentos ecológicos y alimentos modificados genéticamente. En relación con alguna de estas áreas se han realizado informes que demuestran el interés por esta información.Si bien la información en el ámbito que estudia este artículo es, en general, bastante completa, hay cuestiones sobre las que no está tan desarrollada. En otros casos, aunque sí hay un mayor desarrollo, se aprecian problemas relacionados principalmente con las excepciones y la complejidad de algunas de las menciones utilizadas.En algunos casos encontramos la obligatoriedad de proporcionar información en relación con ciertos aspectos, en otros casos existen requisitos concretos para el etiquetado voluntario, y, por último, para otros el etiquetado voluntario sólo tiene que cumplir condiciones generales. Se concluye que, aunque el etiquetado voluntario proporciona información, puede implicar una falta de homogeneidad debido a la existencia de varios tipos de etiquetado con criterios diferentes. Por otra parte, debido a su carácter voluntario, es posible que no se utilice mucho. El establecimiento de requisitos concretos para el etiquetado voluntario en función del tipo de información que proporcione, así como el etiquetado obligatorio, implicarían una mayor coherencia y homogeneidad.En conclusión, aunque se trata de un ámbito en el que se han regulado muchos aspectos, cabe destacar que todavía existen demandas respecto a estos tipos de información alimentaria. Sería deseable una normativa de carácter más sistemático y homogéneo que permitiera dar satisfacción a los derechos de las personas consumidoras y al mismo tiempo proporcionara una mayor seguridad jurídica a los operadores económicos implicados.
BIOSEMIÓTICA: HACIA UNA TEORÍA GENERAL DE LOS SIGNOS DE LA NATURALEZA HUMANA Y NO HUMANA
Authors: ROMERO Javier
Published: April 2020

Resumen: La biosemiótica es la síntesis de la biología y la semiótica,y su propósito principal es mostrar que la semiosis es un componentefundamental de la vida, es decir, que los signos y el significado de los signosexisten en todos los sistemas vivos. La biosemiótica está experimentandoun interés creciente en semiótica, con notables resultados epistemológicos.En este trabajo hacemos un breve análisis de la biosemiótica para resaltarla novedad de esta teoría a la hora de interpretar las señales de la naturalezahumana y no humana. Abstract: Biosemiotics is the synthesis of biology and semiotics, andits main purpose is to show that semiosis is a fundamental component oflife, i. e., that signs and meaning exist in all living systems. Biosemioticsis experiencing a growing interest in semiotics, with importantepistemological results. This paper makes a brief analysis of biosemioticsto highlight the novelty of this theory when interpreting the signs of humanand non-human nature.
EDUCACIÓN Y NUEVAS METODOLOGÍAS COMUNICATIVAS: FLIPPED CLASSROOM
Authors: POZUELO CEGARRA José María
Published: April 2020

Resumen: En los últimos años los docentes han visto cómo ha aumentadoconsiderablemente la dificultad para conseguir una comunicación efectivadentro del aula que conlleve a un proceso de enseñanza-aprendizaje eficaz.Los alumnos actuales, especialmente en Educación Primaria, han adquiridoinconscientemente unas habilidades con las nuevas tecnologías que lespermiten acceder a cualquier tipo de información en pocos minutos. Lasmetodologías actuales deben evolucionar para conseguir que los alumnosadquieran un aprendizaje más significativo. La metodología FlippedClassroom es una de ellas, la cual combina el uso de las TIC con unatransmisión de contenidos a través de vídeos. Abstract: In recent years, teachers have seen how the difficulty ofachieving effective communication into the classroom to get an efficientteaching-learning process has increased considerably. Current students,especially in Primary Education, have acquired skills in new technology inan unconscious way, which let them have access to any kind of informationin a few minutes. Current methodologies should be developed more so thatthat pupils can acquire a more significant learning. The Flipped Classroommethodology is one of them, which combines the use of ICTs with the useof videos to transmit the contents.