bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel Smart Chitosan-Based Formulations as Potential siRNA Nanocarriers for Breast Cancer Theranostic
Authors: Kundapura Srujan , Braim Shwana
Published: November 2023

Cancer remains a major global health concern, particularly with breast cancer ranking among the topmost common forms. the development of effective and safe nanocarriers for siRNA delivery has gained significant attention in the field of cancer therapy. This study aims to develop an innovative smart drug formulation for precise siRNA delivery to breast cancer sites. The resulting formulation, encapsulating siRNA and exhibiting dual pH- and magnetic- responsive properties, present a potential solution. The integration of superparamagnetic iron oxide nanoparticles (SPIONs) within chitosan microspheres, as carriers in magnetically driven drug delivery systems, holds promise for advancing biotherapeutic delivery strategies. This approach enables rapid, site-specific delivery of biotherapeutics facilitated by an external magnetic field. The chitosan coating provided pH-sensitive drug release, while glutaraldehyde and TPP crosslinking ensured bead stability. Successful synthesis evaluated and confirmed via several characterizations including SEM, TEM, DLS, FTIR, and EDS confirmed the formulation's suitability, paving the way for further optimization. Results showed high siRNA encapsulation, loading, and release for specific formulations, highlighting the potential of medium molecular weight chitosan. Chitosan type and crosslinker significantly influenced drug release patterns, while diverse profiles across batches emphasized the importance of precise formulation. These findings suggest that these microspheres have the potential to revolutionize breast cancer treatment by reducing side effects and enhancing therapeutic efficacy.
The Strait of Malacca and Strait of Hormuz: A Brief Historical Review
Authors:   Department of History and Civilization, Abdul Hamid Abu Sulayman Kulliyyah of Islamic Revealed Knowledge and Human Sciences, International Islamic University Malaysia, P.O. Box 10, 50728 Kuala Lumpur, Malaysia, Mansor Majdin Mohamad Firdaus , Osman Rahmah Ahmad H. ,   Department of Arabic Language and Literature, Abdul Hamid Abu Sulayman Kulliyyah of Islamic Revealed Knowledge and Human Sciences, International Islamic University Malaysia, P.O. Box 10, 50728 Kuala Lumpur, Malaysia, Yaapar Md Salleh ,   Department of Literature, School of Humanities, Universiti Sains Malaysia, 11800 USM, Pulau Pinang, Malaysia
Published: November 2023

This study attempts to revisit two prominent trading networks between the Arab world and the Malay archipelago, namely the Strait of Malacca and the Strait of Hormuz, which historically linked the two worlds. This historical linkage is made possible via visitations by the Arab-Persian traders to the Malay world and the Malay traders’ visits to their destinations. Given the geopolitical environments they have experienced in the past and present, there is no denying the immense significance of these straits to Malaysia and the Kingdom of Oman, respectively. They had contributed abundantly in the past to Malaysia and the Kingdom of Oman, as well as to the countries bordering the two straits. Nonetheless, the study argues that given the current unstable world conditions, the safe navigation of both straits is increasingly vulnerable. It also highlights some socioeconomic and political dynamism, which reveal historical changes and continuities that have occurred in the past and present. The situation here seems critical since both straits have established themselves as major world shipping lanes from the west to the east and vice versa. In short, the study investigates the current issues and how small countries like Malaysia and the Kingdom of Oman handle conflict in the most strategic and effective way.
Indonesian Manuscripts at Staatsbibliothek zu Berlin: A Codicological Review
Authors:   Department of Literature, Faculty of Humanities, Universitas Indonesia, Indonesia, Pudjiastuti Titik
Published: November 2023

Old manuscripts are cultural products of the ancestors of modern Indonesians and contain highly valuable cultural information. As such, they were sought after by other nations, who have managed to acquire them in various ways, including by taking them, bartering them with other items or buying them. It is thus no wonder that a lot of Indonesian manuscripts are now housed in various institutions in other countries, including the Staatsbibliothek zu Berlin (STABI) in Germany. This article aims to describe the Indonesian manuscripts that are now housed in STABI and to trace how they ended up there, with a particular focus on the physical condition of the manuscripts using the codicological approach. As the research shows, the Indonesian manuscripts housed in STABI are from various regions, including Java, the Batak lands, Aceh, Bima, Lampung and Makassar, and in the Malay language used all over Southeast Asia. The manuscripts date from the 15th century onwards, and they were acquired as a result of purchase or as gifts from certain institutions or individuals.
Metafizik Melayu Menurut Filsuf Melayu Kerajaan Buddha, Hindu dan Islam
Authors:   Jabatan Pengajian Cina, Universiti Tunku Abdul Rahman (UTAR), Kampus Sungai Long, Selangor, Malaysia, Tee Boon Chuan
Published: November 2023

Makalah ini bertujuan untuk mengupas konsep falsafah atau metafizik Melayu secara khusus dari kurun ke-7 sehingga kurun ke-17 yang menjangkau kerajaan Sriwijaya, Malayu-Singapura dan Aceh dengan karya-karya filsuf Sakyakirti, Dharmakirti, Kuja Ali (melalui narator Hikayat Seri Rama) dan Hamzah Fansuri. Falsafah daripada kerajaankerajaan pelbagai zaman merujuk kepada ilmu tertinggi yang sama iaitu metafizik yang berasaskan konsep sebab dan akibat (causality). Para filsuf bersetuju bahawa alam semesta adalah kesan yang dicipta daripada sebab muktamad, namun ahli falsafah Sriwijaya seperti Sakyakirti dan Dharmakirti dari sekolah Buddha Yogacara mengaitkan perkara ini dengan cita, manakala Kuja Ali dan Hikayat Seri Rama dari tradisi Hindu Samkhya pada zaman Melayu-Singapura menganggap hal ini sebagai purusa, dan Hamzah Fansuri dari tasawuf Islam pada zaman kerajaan Aceh pula merujuknya sebagai Allah SWT. Di sebalik perbezaan itu, pendekatan pengetahuan kendiri yang sama telah diambil oleh semua filsuf kerana mereka mempercayai bahawa “wujud diri” (akibat) adalah tidak berbeza dengan wujud sebab, iaitu dengan menyedari wujud diri, seseorang akan mengenali “wujud hakiki”. Persamaan dan kesinambungan daripada konsep dan pendekatan ini di seluruh kerajaan Sriwijaya sehingga ke Aceh mungkin merupakan tradisi atau jati diri falsafah Melayu yang belum diterokai dan disedari oleh masyarakat falsafah.
Financial development and non-resource economic growth: Empirical evidence from Azerbaijan
Authors: Seyfullayev İlgar
Published: November 2023

Most research on financial development and non-resource economic growth presents a wide range and, in some cases, even conflicting results. Evidence from emerging and resource-rich countries may enrich the scientific discourse with new empirical evidence. Therefore, the study aims to assess the mutual impact of financial development and non-resource economic growth in Azerbaijan. The growth rate of real non-oil gross domestic product (GDP), the share of loans in non-oil GDP, and the share of the broad money in GDP were taken as variables for the model. Monthly variable data from 2005–2022 were processed using the unrestricted vector autoregression model. The study’s results did not provide evidence for long-run causality between the finance sector and non-oil growth. But there are short-run and unidirectional causal relationships – from loans to non-oil growth and from broad money to loans. The results also showed that the increase in loans does not support broad money growth. Policymakers are encouraged to increase incentives for lending to the non-oil sector. Supporting money supply growth through increased deposits and non-cash money could also positively impact non-oil growth through loan channels. The development of the securities market could also open up additional financing opportunities for entrepreneurs in the non-oil sector.
AcknowledgmentsAcknowledgments are expressed to all the scientists whose works have become a theoretical and methodological foundation for the study. It is also necessary to note the Central Bank of the Republic of Azerbaijan, which provides open access to the use of an extensive information base.
Comparison of Perception Differences among Nurses based on Harm Assessment Education in the Patient Safety Classification System
Authors: Lee Kwangmi , Shin Eunhee
Published: November 2023

Background:

Accurate harm assessment is critical in the patient safety event management system, but few studies have been published to support the need for training in harm assessment of patient safety events for nurses.

Objective:

The purpose of this study was to see if there was a difference in the degree of agreement between before and after nurses received training on a patient safety event harm assessment guideline.

Methods:

After participating in online harm assessment education, 65 subjects completed the self-report questionnaire. Data for the general characteristics of the study subjects and the frequency of respondents for each scenario were analyzed using descriptive statistics. Fleiss' kappa was calculated by estimating the inter-rater agreement among respondents for each scenario.

Results:

The agreement value of subjects by Fleiss' Kappa value improved from k = 0.23 before education to k = 0.31 after education, according to the harm assessment. There was no change at k = 0.30 before and after education for the harm period.

Implication for Nursing & Conclusion:

This study’s findings suggest that harm assessment agreement among nurses could be increased through harm assessment education. As a result, case-based education on harm assessment must be expanded, as well as related programs for practical education via patient safety event casebooks.
Risk Factors of Acute Coronary Syndrome: The Experience from Iran
Authors: Raesi Rasoul , Saleki Sajad , Heydari Sina , Behzadi Ghazaleh , Mehralizade Akbar , Daneshi Salman
Published: November 2023

Aims:

This study was conducted with the aim of identifying the risk factors of coronary artery disease in patients referred to Imam Khomeini Hospital in Jiroft.

Background:

Acute coronary syndrome (ACS) is a spectrum of symptoms compatible with acute myocardial ischemia. Understanding these factors can have an effective impact on the prevention, diagnosis, and management of ACS.

Methods:

This is a descriptive study. Participants in this study were all patients diagnosed with acute coronary syndrome and acute myocardial infarction in 2020. Data collection was done by reviewing patients' clinical records. Data analysis was performed by SPSS version 21.

Results:

Out of a total of 228 patients, 149 (65%) were male and 79 (35%) were female. 88% of patients complained of heart pain upon arrival, 43% had a history of drug abuse, 98.2% had retrosternal pain, 48.1% had an average length of hospitalization of four days, 32% were under ischemic treatment, and 68% were under ischemic treatment. They were on thrombolytic therapy. The majority of patients (65.1%) had an EF greater than 40%. 13.9% mortality, 18.9% discharge with survival and recovery, 62.7% recovery and referral to a higher center to complete treatment and angiography, and 4.5% leaving the hospital with It was personal satisfaction.

Conclusion:

The main risk factors related to chest pains in the Jiroft region and the reason for more patients going to the hospital include hypertension, high blood sugar on arrival, low WMR, high BMI, drug abuse, leukocytosis, and non-compliance with post-treatment recommendations.
Clinical Efficacy of Nutritional Supplements in Atopic Dermatitis: Systematic Review
Authors: Weber Isaac , Woolhiser Emily , Keime Noah , Wasvary Margaret , Adelman Madeline J , Sivesind Torunn E , Dellavalle Robert P
Published: November 2023

Background

Atopic dermatitis (AD), also known as eczema, is a chronic inflammatory skin condition that presents with symptoms of intense pruritus, dryness, and erythema. Dissatisfaction with first-line therapies for AD, the desire to avoid steroids, and the extreme cost of effective biologics have created a demand for alternative treatment options such as oral vitamins and nutritional supplements.

Objective

The purpose of this review was to assess the effectiveness of oral nutritional supplements, pre- and probiotics, and vitamin deficiencies and supplements on AD symptomology and clinical course.

Methods

We searched Scopus, PubMed, and MEDLINE (Ovid interface) for English-language articles published between 1993 and 2023. The final search was conducted on June 22, 2023. The search terms comprised the following: “(Atopic Dermatitis or Atopic Eczema) AND (supplement OR vitamin OR mineral OR micronutrients OR Fish Oil OR Omega Fatty Acid OR Probiotics OR Prebiotics OR apple cider vinegar OR collagen OR herbal OR fiber).”

Results

A total of 18 studies—3 (17%) evaluating vitamins, 4 (22%) evaluating herbal medicine compounds, 2 (11%) evaluating single-ingredient nutritional supplements, and 9 (50%) evaluating pre- and probiotics—involving 881 patients were included in this review.

Conclusions

Overall, there is weak evidence to support any one nutritional supplement intervention for the alleviation of AD symptoms. Multiple trials (4/18, 22%) showed promise for supplements such as Zemaphyte, kefir, and freeze-dried whey with Cuscuta campestris Yuncker extract. The most evidence was found on the effectiveness of probiotics on the clinical course of AD. Lactiplantibacillus plantarum, Ligilactobacillus salivarius, and Lactobacillus acidophilus specifically showed evidence of efficacy and safety across multiple studies (6/18, 33%). However, larger, more extensive randomized controlled trials are needed to determine the true effectiveness of these supplements on the broader population.

Trial Registration

PROSPERO CRD42023470596; https://tinyurl.com/4a9477u7
Behavioral Activation–Based Digital Smoking Cessation Intervention for Individuals With Depressive Symptoms: Randomized Clinical Trial (Preprint)
Authors: Dahne Jennifer , Wahlquist Amy E , Kustanowitz Jacob , Natale Noelle , Fahey Margaret , Graboyes Evan M , Diaz Vanessa A , Carpenter Matthew J
Published: November 2023

BACKGROUND

Depression is common among adults who smoke cigarettes. Existing depression-specific cessation interventions have limited reach and are unlikely to improve smoking prevalence rates among this large subgroup of smokers.

OBJECTIVE

This study aimed to determine whether a mobile app–based intervention tailored for depression paired with a mailed sample of nicotine replacement therapy (NRT) is efficacious for treating depression and promoting smoking cessation.

METHODS

A 2-arm nationwide remote randomized clinical trial was conducted in the United States. Adults (N=150) with elevated depressive symptoms (Patient Health Questionnaire-8≥10) who smoked were enrolled. The mobile app (“Goal2Quit”) provided behavioral strategies for treating depression and quitting smoking based on Behavioral Activation Treatment for Depression. Goal2Quit participants also received a 2-week sample of combination NRT. Treatment as usual participants received a self-help booklet for quitting smoking that was not tailored for depression. Primary end points included Goal2Quit usability, change in depression (Beck Depression Inventory-II) across 12 weeks, and smoking cessation including reduction in cigarettes per day, incidence of 24-hour quit attempts, floating abstinence, and 7-day point prevalence abstinence (PPA).

RESULTS

In total, 150 participants were enrolled between June 25, 2020, and February 23, 2022, of which 80 were female (53.3%) and the mean age was 38.4 (SD 10.3) years. At baseline, participants on average reported moderate depressive symptoms and smoked a mean of 14.7 (SD 7.5) cigarettes per day. Goal2Quit usability was strong with a mean usability rating on the System Usability Scale of 78.5 (SD 16.9), with 70% scoring above the ≥68 cutoff for above-average usability. Retention data for app use were generally strong immediately following trial enrollment and declined in subsequent weeks. Those who received Goal2Quit and the NRT sample reported lower mean depressive symptoms over the trial duration as compared to treatment as usual (difference of mean 3.72, SE 1.37 points less; P=.01). Across time points, all cessation outcomes favored Goal2Quit. Regarding abstinence, Goal2Quit participants reported significantly higher rates of 7-day PPA at weeks 4 (11% vs 0%; P=.02), 8 (7-day PPA: 12% vs 0%; P=.02), and 12 (16% vs 2%; P=.02).

CONCLUSIONS

A mobile app intervention tailored for depression paired with a sample of NRT was effective for depression treatment and smoking cessation. Findings support the utility of this intervention approach for addressing the currently unmet public health treatment need for tailored, scalable depression-specific cessation treatments.

CLINICALTRIAL

ClinicalTrials.gov NCT03837379; https://clinicaltrials.gov/ct2/show/NCT03837379
Japanese Perception of Brain Death and Implications for New Medical Technologies: Quantitative and Qualitative Social Media Analysis (Preprint)
Authors: Vargas Meza Xanat , Oikawa Masanori
Published: November 2023

BACKGROUND

Brain death has been used to decide whether to keep sustained care and treatment. It can facilitate tissue, organ, and body donation for several purposes, such as transplantation and medical education and research. In Japan, brain death has strict diagnostic criteria and family consent is crucial, but it has been a challenging concept for the public since its introduction, including knowledge and communication issues.

OBJECTIVE

We analyzed data across YouTube and Twitter in Japan to uncover actors and assess the quality of brain death communication, providing recommendations to communicate new medical technologies.

METHODS

Using the keyword “脳死” (brain death), we collected recent data from YouTube and Twitter, classifying the data into 5 dimensions: time, individuality (type of users), place, activity, and relations (hyperlinks). We employed a scale to evaluate brain death information quality. We divided YouTube videos into 3 groups and assessed their differences through statistical analysis. We also provided a text-based analysis of brain death–related narratives.

RESULTS

Most videos (20/61, 33%) were uploaded in 2019, while 10,892 tweets peaked between July 3 and 9, 2023, and June 12 and 18, 2023. Videos about brain death were mostly uploaded by citizens (18/61, 27%), followed by media (13/61, 20%) and unknown actors (10/61, 15%). On the other hand, most identified users in a random sample of 100 tweets were citizens (73/100, 73%), and the top 10 retweeted and liked tweets were also mostly authored by citizens (75/100, 75%). No specific information on location was uncovered. Information videos contained guides for accreditation of the National Nursing Exam and religious points of view, while misinformation videos mostly contained promotions by spirituality actors and webtoon artists. Some tweets involved heart transplantation and patient narratives. Most hyperlinks pointed to YouTube and Twitter.

CONCLUSIONS

Brain death has become a common topic in everyday life, with some actors disseminating high-quality information, others disseminating no medical information, and others disseminating misinformation. Recommendations include partnering with interested actors, discussing medical information in detail, and teaching people to recognize pseudoscience.
Analysis of the perceptions, competencies, and educational needs for global health among medical students in South Korea: Cross-sectional study using the Borich needs assessment and the Locus for Focus model (Preprint)
Authors: Kim Songrim , Kyung Sun Young , Park Ie Byung , Yune So Jung , Park Kwi Hwa
Published: November 2023

BACKGROUND

Global health, which pursues health equity for all across country boundaries, is essential in medical education to cultivate future doctors. Global health education (GHE) is still in its early stages in Korean medical education; thus, it is necessary to identify the level of awareness and needs assessment of medical students in relation to GHE.

OBJECTIVE

The purpose of this study was to examine perceptions of GHE among medical students and their involvement in global health activities and identify priorities of educational needs for developing GHE programs.

METHODS

This study was cross-sectional and conducted through an online survey for medical students. The participants were students attending medical schools nationwide, and the final analysis target was 678 of the respondents. The survey developed questionnaires necessary for research purposes regarding global health-related experiences and perceptions, level of awareness of global health competencies (GHC), and needs assessments. The frequency analysis, chi-squared test, and independent t-test were used to explore global health-related participation and awareness. Educational priorities for GHE were also analyzed using the Borich Needs Assessment Model and the Locus for Focus Model.

RESULTS

In total, 60.6% (411/678) of Korean medical students agreed on the need for GHE, whereas 12.1% (82/678) agreed on the appropriateness of GHE in the current medical school curriculum, indicating a perception gap between the necessity and the status. At the current level of awareness of global health and GHC, we identified statistically significant differences according to gender, participation in global health activities, and GHE. In the analysis of the educational needs of GHC, all items of GHC had statistically significant differences between the importance level and the current level, and priorities were derived.

CONCLUSIONS

Discussions on fostering prospective doctors with GHC in medical education have been ongoing, but further studies are needed due to insufficient research on GHE in Korean medical education. Therefore, we expect the findings of this study to be used in Korean medical education as fundamental data to prepare a hereafter research foundation for GHE and discuss systematic GHE based on GHC. In addition, the Korean case of this study will be able to provide practical information on GHE in medical education in Asian countries.
Costo en el cuidado de enfermería a personas con úlcera vascular venosa
Authors: Ambrosio-Ramírez Cristian Camilo , Medina-Garzón Mauricio
Published: November 2023

Introducción: El cuidado de las úlceras vasculares venosas se ha considerado un problema de salud pública por su alta incidencia e impacto social y económico que genera. Objetivo: Determinar los costos directos del cuidado de enfermería en personas con úlcera vascular venosa atendidas por un prestador de servicios de salud en la ciudad de Bogotá. Materiales y métodos: Estudio observacional, descriptivo, retrospectivo, realizado entre el 1 enero de 2019 y el 31 de enero de 2020; el cual se basó, en la revisión de historias clínicas de personas con úlcera vascular venosa. La muestra estuvo conformada por 52 historias clínicas, seleccionadas mediante un instrumento de valoración de enfermería. Las variables que se analizaron fueron la edad y el sexo, utilizando estadística descriptiva y el análisis del costo. Resultados: El sexo predominante fue el femenino (69,24%) y la edad promedio de 64 años. El costo directo fue de 70.109.504.76 COP y la estimación promedio 1.348.259 COP, valor que incluyó el costo de apósitos, elastocompresión, limpieza y consulta. Conclusión: Los costos en el cuidado de las úlceras vasculares venosas están inmersos en los paquetes de atención, que incluyen los costos de curación y consulta; sin embargo, no son explícitos para enfermería.
Random mating in a hybrid zone between two putative climate-adapted bird lineages with predicted mitonuclear incompatibilities
Authors: Austin Lana , Amos J. Nevil , Robledo-Ruiz Diana , Zhou Jessica , Clarke Rohan , Pavlova Alexandra , Sunnucks Paul
Published: November 2023

Mitonuclear interactions have been proposed as evolutionary drivers of
sexual reproduction, sexual selection, adaptation, and speciation. We
investigated the role of pre-mating isolation in maintaining functional
mitonuclear interactions in a wild population with divergent sets of
proposed co-adapted mitonuclear genotypes. Two lineages have been
identified in the eastern yellow robin Eopsaltria australis - putatively
climate-adapted to ‘inland’ and ‘coastal’ climates. The lineages differ
by ~7% of mitochondrial DNA positions, whereas nuclear
genome differences are concentrated into a sex-linked region enriched
with mitochondrial genes. This pattern can be explained by female-linked
selection accompanied by male-mediated gene flow across the narrow
hybrid zone in which the two lineages coexist. It remains unknown
whether lineage divergence is driven by intrinsic incompatibilities
(particularly in females, under Haldane’s rule), extrinsic
incompatibilities, or both. We tested whether non-random mating with
respect to partners’ mitolineages or Z-linked variation could facilitate
lineage divergence. We used field data, Z-linked and mitolineage genetic
markers from two locations where the lineages hybridize, to test whether
females choose to mate with (1) males of their own mitolineage and/or
bearing similar Z-linked variation, as might be expected if hybrids
experience intrinsic incompatibilities, or (2) putatively
locally-adapted males, as expected under environmental selection.
Comparisons of field observations and simulations present no evidence of
non-random mating: the observed reduced female gene flow likely operates
via post-mating isolation. Future studies testing for female-biased
mortality at different life stages and female habitat selection should
clarify the mechanisms of selection.
Benchmarking Diabetes Technology Use Among 21 U.S. Pediatric Diabetes Centers
Authors: Prahalad Priya , Hardison Holly , Odugbesan Ori , Lyons Sarah , Alwazeer Mohammed , Neyman Anna , Miyazaki Brian , Cossen Kristina , Hsieh Susan , Eng Donna , Roberts Alissa , A. Clements Mark , Ebekozien Osagie , T1D Exchange Quality Improvement Collaborative the
Published: November 2023

The American Diabetes Association’s Standards of Care in Diabetes recommends the use of diabetes technology such as continuous glucose monitoring systems and insulin pumps for people living with type 1 diabetes. Unfortunately, there are multiple barriers to uptake of these devices, including local diabetes center practices. This study aimed to examine overall change and center-to-center variation in uptake of diabetes technology across 21 pediatric centers in the T1D Exchange Quality Improvement Collaborative. It found an overall increase in diabetes technology use for most centers from 2021 to 2022 with significant variation.
Burnished and Luminous-Hyalinising Clear Cell Carcinoma
Authors: Bajajj Anubha
Published: November 2023

Hyalinising clear cell carcinoma is a unique, exceptionally encountered, malignant neoplasm of salivary glands commonly incriminating minor salivary glands, especially intraoral glands. Typically, tumefaction exhibits genomic fusion EWSR1: ATF1. Besides, various fusion oncogenes or concurrent, variant genetic fusions are encountered.
Challenges of Veiled Woman in Society
Authors: Sabrina Rifdah , Najmah Lailan , Afrina Meti
Published: November 2023

This research aims to analyze the challenges faced by women who wear the veil in society. This research uses a qualitative method with a phenomenological approach, research data was taken through direct interviews with ten informants. All interview data was then analyzed thematically using Miles and Huberman qualitative data analysis. Research findings show that there are four challenging factors faced by women who wear the niqab, namely i) maintaining consistency in wearing the niqab, ii) difficulty in carrying out activities, iii) not getting permission from parents, iv) getting ridiculed by society. The results of this research can be used as initial data for subsequent researchers in studying different issues related to this problem as well as various other issues that are relevant to this context.
Companion Skills for Local Food Tourism Village Facilitators to Improve the Family Economy of Ngemplak Dusun, Sumber Suko Village, Wagir District, Malang
Authors: Purwito Lasi , Zulkarnain Zulkarnain , Miroso Raharjo Kukuh , Avrilianda Decky
Published: November 2023

Ngemplak Hamlet is one of the hamlets in Sumbersuko village in Wagir District, especially located on the slopes of Mount Kawi. Wagir District is located between the slopes of Mount Kawi. This hamlet is one of the hamlets in Sumbersuko village that has physical potential in terms of abundant natural resources, especially in the food sector. The people of Ngemplak Hamlet are able to make various food preparations that come from local food ingredients. Nowadays, tourists are starting to like tourist attractions that not only provide natural beauty but also community interaction. The local food village tourism facilitator has the role of providing information to tourists about the local culinary specialties that exist and the typical dishes of the people in Sumbersuko Village that are served to tourists. The concept of local food tourism villages will indirectly require the community, especially village youth, to act as facilitators of local food. However, the lack of information regarding the potential of villages in Ngemplak hamlet by the community, especially teenagers, especially regarding local food, is one of the obstacles when tourists come to their area. There is a need for assistance to prepare teenagers in Ngemplak Hamlet to be trained to increase their knowledge and skills as local food facilitators, which can be an added value for visiting tourists. The objectives of community service are as follows: (1) Empowering teenagers as facilitators of local food tourism villages in increasing their knowledge and skills in processing local food in Ngempalk Village Hamlet; (2) Provide assistance to the management and members of the local food tourism village in Ngemplak Hamlet, Sumbersuko Village in introducing the tourism village through social media; (3) Provide assistance to local food education tourism village administrators in managing the tourism village so that it can run and survive as one of the tourist village destinations in Malang Regency.
Genotyping of Sumatera local variety of citrus using random amplified polymorphism DNA (RAPD) technique
Authors: Sari Rinti Mutiara , Achyar Afifatul A , Ahda Yuni , Hilda Putri Dwi
Published: November 2023

Indonesia has local varieties of citrus that are no less than imported citrus, especially in terms of fruit freshness. However, people are more interested in the color of citrus peel so people prefer imported citrus to local citrus, especially in Sumatera. Therefore, it is necessary to carry out efforts to conserve and improve the characteristics of these citrus to improve their quality through plant breeding. This study aims to optimize DNA isolation methods for citrus fruit samples with Chelex-TE and to determine the genetic profile of local Sumatera citrus and imported citrus using the genotyping RAPD. The samples used were several local citrus in Sumatera (Citrus Siam Mountain Omeh, Citrus Madu, Citrus Keprok Maga, Citrus Keprok Brastepu and Citrus Pasaman) and imported Citrus (Citrus Sunkist, Citrus Clemengold, Citrus Murkot and Citrus Wokam). DNA was isolated using the 10% Chelex-TE method which was optimized for several parameters such as grain size, fruit skin and leaves. RAPD was performed using 10 RAPD primers. The results showed that the optimum 10% Chelex Chelex-TE isolation method was a sample size of 1 grain. The amplification of local Sumatran citrus and imported citrus using 10 single primers produced polymorphic bands. The value of jaccard's similarity indicates that the five samples of Sumatera local variety of citrus and imported citrus have high genetic variation. Indonesia has local varieties of citrus that are no less than imported citrus, especially in terms of fruit freshness. However, people are more interested in the color of citrus peel so people prefer imported citrus to local citrus, especially in Sumatera. Therefore, it is necessary to carry out efforts to conserve and improve the characteristics of these citrus to improve their quality through plant breeding. This study aims to optimize DNA isolation methods for citrus fruit samples with Chelex-TE and to determine the genetic profile of local Sumatera citrus and imported citrus using the genotyping RAPD. The samples used were several local citrus in Sumatera (Citrus Siam Mountain Omeh, Citrus Madu, Citrus Keprok Maga, Citrus Keprok Brastepu and Citrus Pasaman) and imported Citrus (Citrus Sunkist, Citrus Clemengold, Citrus Murkot and Citrus Wokam). DNA was isolated using the 10% Chelex-TE method which was optimized for several parameters such as grain size, fruit skin and leaves. RAPD was performed using 10 RAPD primers. The results showed that the optimum 10% Chelex Chelex-TE isolation method was a sample size of 1 grain. The amplification of local Sumatran citrus and imported citrus using 10 single primers produced polymorphic bands. The value of jaccard's similarity indicates that the five samples of Sumatera local variety of citrus and imported citrus have high genetic variation.
Performance measures in Alberta's labour programming
Authors: Barnetson Bob
Published: November 2023

This study examined the validity of performance indicators used to monitor labour relations programming in the Canadian province of Alberta. Specifically, the study examined whether the indicators were meaningfully related to the government’s overarching goal of “fair, safe and healthy workplaces” and whether the assumptions embedded in each measure were true. Overall, the indicators were found to have definitional and causal defects. These defects suggested the indicators are not meaningfully related to the government’s overarching goal. Further analysis of the indicators suggested that, in some cases, they create perverse incentives for field staff and obscure important outcomes that bear upon government goals.
The 2007 Provincial Election in Quebec
Authors: Bélanger Éric
Published: November 2023

The 2007 provincial election in Quebec may be considered a milestone in recent Quebec politics. For the first time since 1878, voters elected a minority government in the province (Jean Charest’s Liberals), a third party (ADQ) replaced the Parti Québécois (PQ) as Official Opposition, and the PQ had its worst showing in 37 years. The pre-campaign was marked by the “reasonable accommodations” debate, which gave the ADQ the boost it needed to rival the two main parties. The incumbent Charest government suffered from its low popularity, due to what was largely perceived as a disappointing record. The PQ’s loss of support was mostly attributable to its new leader André Boisclair’s lack of appeal and to the party’s insistence on holding another referendum on Quebec sovereignty. Quebec’s new three-party system may last for some time, due to each party having strong and relatively well-defined regional support bases.
The Antecedents to Cascadia as a Cross Border Region
Authors: McDougall A K , Phillips Lisa
Published: November 2023

For the short period from 1834 to 1863, the Pacific Northwest, centered in Cascadia, was an entity in the global economy. The region became a coherent economic unit under the management of the Columbia District of the Hudson’s Bay Company, which developed an economic hinterland, a coherent economic and trade strategy, an aggressive marketing agenda and control of marketable resources in the region. It strategically built a resource base to meet market needs and played an extensive entrepreneurial function, for example selling Finish boots in California in 1840 and Puget Sound grain in western Siberia by 1843. This paper traces the broad outline of the rise and fall of this economic empire and draws attention to the role of state power, manifested at the levels of identity and legal construction, in ending the coherence of that regional entity. In a time when the logic of Cascadia on environmental and regional grounds is apparent to many, this paper highlights how the border and the attendant identities of political actors divided and ended its coherence. Its demise may offer insight into the forces which bolster the border which divides it today.
Beyond Sex and Saxophones: Interviewing Practices and Political Substance on Televised Talk Shows
Authors: Bastien Frederick
Published: November 2023

The goal of this paper is to assess the contribution of infotainment and entertainment television talk shows by comparing political interviews on these TV shows with current affairs programs. Few political scientists have examined political interviews, in general, and political interviews on entertainment outlets, in particular. Moreover, these studies are often focused on the sorts of topic participants talk about in such programs. On the basis of literature developed by scholars in sociolinguistics and journalism, we expand the scope of our study to the assessment of questions asked by the interviewers and answers provided by the politicians. We perform a quantitative content analysis of political interviews to compare the behavior of these speakers on infotainment and entertainment programs with those on current affairs programs. Our results show that hosts on infotainment programs are no less rigorous than their counterparts on information programs, especially when the interview is centered on policy issues. We conclude that scholars interested in these questions should turn to studies in sociolinguistics and journalism to build a relevant analytical frame.
Reframing Campaigning: Communications, the Media and Elections in Canada
Authors: Nesbitt-Larking Paul
Published: November 2023

This article is a critical assessment of Canadian perspectives on the role of the media in electoral behaviour, notably on the roles media play in setting or responding to the agenda in the heat of election campaigns. Research into the role of the media in election campaigns has been conducted within the broadly behaviouralist tradition of political scientific research. The article begins with a brief contextualization of the behaviouralist research tradition in Canada. Within the specific context of Canadian history and its social structure, the introduction explains how the very questions that Canadians have posed regarding media/campaign interactions have been undertaken in a range of research traditions that problematize fields of causality with greater complexity than is possible in the largely positivist behaviouralist paradigm. Three such research traditions are those of “Culture, Ideology, and Discourse,” “Political Economy/Technology,” and “Legal-Institutional Analyses.” The second section of the article highlights important Canadian methodological and empirical contributions to behaviouralism. The general importance of campaign effects, the impact of leader-centred media priming, the methodological innovation of the rolling cross-section sample design, and advances in agenda setting research are identified in this section. The third section of the article, on Culture, Ideology, and Discourse, illustrates general patterns of contrast between the Canadian and American political cultures through an exploration of the comparative role of negative and attack advertisements in election campaigns. This section illustrates instances of how the limits established in the Canadian political culture influence media decisions and how the discourses of media coverage reflect cultural realities. The fourth section of the article illustrates how facets of the Political Economy of Canada exert an impact on media/ campaign interactions. This section explores the media/campaign interaction from both sides. First, the changing impact of campaign financing/campaign spending on media reportage is assessed, and then the implications of shifting patterns of media ownership on campaign coverage is considered. Do either set of changing relations affect the shaping of the media agenda? Finally, the political economy of the new Information and Communications Technologies is investigated in the context of the Toronto School of Communication. The fifth and final section of the article undertakes the task of situating media/campaign interactions within the Legal-Institutional regulatory context of the Canadian state. The impact of the Canada Elections Act and other legislation is undertaken around matters such as freedom of expression, access to information, advertising, spending, and public support for political parties and candidates.
The Internet and Electronic Democracy in Canada: Reaching the Limits of E-Government and the False Promise of Digital Democracy?
Authors: Lacharite J.R.
Published: November 2023

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Institutionalized Inhibition: Examining Constraints on Climate Change Policy Capacity in the Transport Departments of Ontario and British Columbia, Canada
Authors: Perl Anthony , Newman Joshua
Published: November 2023

This paper examines the interaction between

transportation policy and climate change policy in two Canadian

provinces, British Columbia and Ontario. The concept

of policy capacity is used to qualitatively measure the

effectiveness of instruments in advancing goals in an area

where established policy paradigms may not be congruent

with new initiatives. A review of official policy documents

and budgetary information on policy-related spending, as

well as primary interviews with policy managers in relevant

provincial ministries, reveals that overlapping policy goals

and instruments may have created a situation of institutionalized

policy inhibition, in which conflicting layers of policy

goals and instruments constrain the available policy capacity.
The Importance of Context: The Effect of the Market on the Framing of Elections at the Subnational Level in Canada
Authors: Sampert Shannon , Petit-Vouriot Adelina
Published: November 2023

In Canadian media studies, very little research has been done on how elections at the subnational level are covered by newspapers. This paper analyzes the way major newspapers in six Canadian capitals covered provincial elections between 2011 and 2012. The findings were interesting in that they underscored the importance of context in news coverage. Rather than a formulaic game frame focus, with an adherence to who’s winning and who’s losing, our study determined that each newspaper had a distinct voice and focus in their news coverage. This adds a new and interesting dimension to the study of election coverage in Canada.
Problems of power transmission accident rate (on example of JSC "Omskenergosbyt" )
Authors: Naumov I. V.
Published: November 2023

A study and analysis of electric power transmission through the JSC Omskenergosbyt electric networks over the period 2014 – 2022 have been carried out. The structural and balance features of the company are analyzed, the characteristics of the key elements of the studied electrical networks are given, with a number of shortcomings in the disclosure of information noted. Based on public information on the accident rate in the company's electrical networks, an estimate has been made of the number of emergency situations that occurred during the period under study, as well as the magnitude of electrical power under-supply caused by these interruptions. The classification of emergency damages according to the amount of electrical power under-supply as a result of these failures has been made. The percentages of such failures are determined. Various methods for predictive assessment of power supply reliability level in the company's networks are analyzed, and a conclusion is made about the applicability of predictive models of statistical methods. Autoregressive equations have been obtained, the analysis of which allowed to have numerical predictive values of the number of possible emergency failures broken down by months of 2023. The influence of the seasonal component on the number of emergencies during the period under study has beenis considered.General scientific methods, numerical methods of analysis, statistical and cybernetic methods of making predictive models were used in the study. Excel spreadsheet technologies, MATLAB software environment, as well as the Oracle software were used as computational tools. The results obtained may be of interest to chief executives of power grid companies , as well as researchers and engineers engaged in research in the field of power supply reliability.
Risk assessment in case of process disturbances at oil and gas complex enterprises
Authors: Babanova I. S.
Published: November 2023

In the conditions of oil and gas complex enterprises, the main issues in the discussion of development strategies are reliable and high-quality power supply to the most critical consumers in a market economy. This is facilitated by the constant challenges that individual companies encounter when they face issues of improving the energy efficiency of specific production processes, developing and implementing measures aimed at reducing costs while maintaining the volume of products, reducing the downtime of individual equipment, finding and eliminating the root causes of process disturbances. At this stage, the specialists responsible for reliability need to have not only modern competencies, but also the ability to justify and make decisions in a limited time. Thus, the analysis and monitoring of the occurrence of process disturbances at enterprises of the oil and gas complex with subsequent risk assessment becomes particularly important and relevant, and the role of specialists with such competencies increases many times, as problems arise with the hierarchy and classification of risks corresponding to real operating conditions. This article provides an overview of methods for investigating process disturbances, provides the main results of assessing the risks of process disturbances for power grids of different voltage levels, provides a quantitative assessment of risks depending on the identified root causes. Recommendations are given on the identified problems, including the analysis of individual indicators of reliability of power supply to industrial enterprises. The proposed solutions for the application of a matrix approach to assessing the risks of process disturbances in the power supply system of oil and gas complex enterprises will reduce the existing accident rate by analyzing the main causes of process disturbances and, as a result, increase the energy intensity of the manufactured product. Additionally, the adaptation of this method within the framework of the operation of such enterprises will allow managing the reliability of power supply systems.