bluuebunny/crossref_metadata_2025 huggingface dataset:
Особливості лікування хворих похилого віку: досвід застосування Олатропілу® для корекції когнітивної та вегетативної дисфункцій на фоні артеріальної гіпертензії
Authors: Kuzminova N. V. , Osovskaya N. Y. , Knyazkova I. I.
Published: April 2023

Вивчали клінічну ефективність та вплив комбінованої антигіпертензивної терапії з включенням церебропротектора Олатропілу® на рівень артеріального тиску (АТ), показники нейрокогнітивного тестування, вегетативний статус у хворих з артеріальною гіпертензією (АГ) похилого віку і когнітивними порушеннями (КП). Під спостереженням знаходилось 75 хворих з АГ похилого віку (67,4 року ± 3,1 року), 37 чоловіків і 38 жінок. Критерієм включення у дослідження була наявність у хворих з АГ і КП легкого та помірного ступеня. В основну групу ввійшло 39 хворих, які, крім комбінованої антигіпертензивної терапії (АГТ), отримували препарат Олатропіл® (0,25 г пірацетама та 0,125 г аміналону; виробництво OlainFarm, Латвія) по 1 капсулі 3 рази на день протягом 3 міс. Групу порівняння становили 36 хворих, які отримували тільки адекватну, індивідуально підібрану, аналогічну за складом АГТ, як і хворі основної групи, проте без включення Олатропілу®. Групи були порівнянні за віком, статтю, антропометричними параметрами, діагнозом, тривалістю АГ, проявами і ступенем КП. Всім пацієнтам, включеним в дослідження, проводили повне клініко-лабораторне та інструментальне дослідження із застосуванням методів нейрокогнітивного тестування й оцінки вегетативної дисфункції за сучасними вимогами до призначення лікування та через 12 тиж від його початку. Контрольну групу становили 26 клінічно здорових осіб відповідного віку та статі. Результати клінічної оцінки когнітивної функції, психоневрологічного стану та вегетативного статусу хворих з АГ та КП похилого віку в динаміці лікування свідчили про високу ефективність запропонованої комбінованої АГТ з включенням церебропротектора Олатропілу®. Крім нормалізації АТ і психоемоційного стану, визначено достовірне зменшення когнітивного дефіциту (покращання пам’яті, прискорення швидкості сенсомоторних реакцій, підвищення стійкості й концентрації уваги) та проявів вегетативної дисфункції при задовільному сприйнятті призначеного лікування і відсутності побічних реакцій. Отримані результати дозволяють рекомендувати включення церебропротектора Олатропілу® до комплексної терапії хворих похилого віку з АГ і КП для корекції когнітивної та вегетативної дисфункцій.
PERAN EMOTIONAL FREEDOM TEHNIQUE (EFT) DALAM MENGATASI KECEMASAN ORANG TUA DALAM PEMBELAJARAN BERBASIS ONLINE
Authors: Ni'mah Jumrotun , Insani Uswatun , Supriatun Evi
Published: April 2023

Pembelajaran online merupakan pembelajaran tanpa tatap muka secara langsung antar guru dan siswa. Dengan adanya pembelajaran online seringkali membuat orang tua menjadi cemas. Kecemasan merupakan keadaan gelisah, ketidaktentuan, atau rasa takut yang menjadi manifestasi respon psikologis atau fisiologi individu dari keadaan yang tidak menyenangkan atau mengancam. Pengabdian masyarakat ini bertujuan untuk meningkatan pengetahuan guru dan orang tua tentang cara mengatasi kecemasan  dengan terapi Emotional Freedom Tehnique (EFT). EFT merupakan teknik penyembuhan emosional yang juga  ternyata dapat menyembuhkan gejala-gejala penyakit  fisik.” Prinsip kerja EFT adalah menyelaraskan dan memperbaiki kembali sistem energi dalam tubuh yang terganggu, lewat stimulasi  pada titik-titik energi tubuh yang disebut meridian dengan menggunakan tapping (ketukan ringan). Orang tua siswa menyatakan adanya penurunan kecemasan setelah diberikan EFT dengan diekspresikan rasa bersyukur dan menerima dengan ikhlas keadaan yang dialami, khususnya pembelajaran online yang membutuhkan pendampingan ekstra  dari orang tua untuk membantu siswa dalam mencapai target kompetensi belajar.
СТРЕСОСТІЙКІСТЬ ЯК ПРОФЕСІЙНА ЯКІСТЬ ФАХІВЦЯ СОЦІАЛЬНОЇ РОБОТИ
Authors: НОВАК Микола
Published: April 2023

У статті розглянуто теоретичні аспекти особливостей розвитку стресостійкості як професійної якості фахівців соціальної сфери. Уточнено сутність понять «стрес», «стресостійкість», «копінг-стратегії», «професійний стрес»; охарактеризовано взаємозв’язок розвитку стресостійкості фахівців з їхніми індивідуальними психічними процесами і якостями; досліджено особливості професійної діяльності соціальних працівників та їх вплив на розвиток стресостійкості. Автором статті обґрунтовано необхідність застосування працівниками соціальної сфери методів саморегуляції психічних станів (аутогенне тренування, медитацію, психологічні тренінги) для зняття психічного напруження та допомоги у подоланні складних ситуацій, що супроводжують їхню професійну діяльність.
Diabetes disease prediction using firefly optimization-based cat-boost classifier in big data analytics
Authors: Geo Jenefer G. , Deepa A.J.
Published: April 2023

Globally, diabetes directly causes 1.5 million fatalities each year. It is necessary to predict such diseases at an earlier stage and cure them. Since modern healthcare data comprises huge amounts of information, it is tough to process such data in conventional databases. Previously, various machine learning (ML) algorithms were used to predict diabetics, and their performance was evaluated. But still, those existing algorithms result in poor accuracy and performance.This work proposes a FOCB (Firefly Optimization-based CatBoost) classifier for predicting diabetes. The PIMA Indian diabetic dataset has been taken as the input dataset. The proposed FOCB algorithm has been compared with various machine learning algorithms. From the results, we can see that the FOCB classifier gives the best accuracy of 96% with improved performance. The proposed system has been compared with other FO-based machine learning algorithms like NB, KNN, RF, AB, GB, XGB, CNN, DBN, and CB, and it has been proven that CB based on FO produces better accuracy with less hamming loss.
Developing and Evaluating the Marriage Education Program: The Example of the Turkish Cypriot Community
Authors: Salman Nihal
Published: April 2023

In this study, the marriage education needs of individuals living in Northern Cyprus were determined, a marriage education program (EEP) was developed in line with the identified needs, and the effectiveness of the program was evaluated. In the study, a single-group quasi-experimental design was used in the implementation and evaluation of the program. The developed program was implemented as in-service training for the employees of the Nicosia Turkish Municipality. Participants of the trainings are 20 volunteers. Qualitative and quantitative methods were used to evaluate the effectiveness of the EEP. Qualitative data were analyzed with the "Coding Comparison Query" method available in the NVivo R1 program. Independent sample t-test was used to determine the attitudes and beliefs of the participants about marriage before and after the EEP. The findings of the research are as follows; EEP significantly improved the marriage attitudes and beliefs of married individuals. The qualitative and quantitative data obtained from the subjects supported each other. It has been concluded that EEP is effective. Considering the findings obtained from this study, EEP in Northern Cyprus can be organized by the Ministry of National Education and Culture (MEKB) for parents in schools in the context of adult education. EEP within formal education can be given by MEKB in the form of courses in accordance with the development levels of the students. In addition, EEP can be given to citizens by municipalities and non-governmental organizations as public education.
Preliminary investigation on the occurrence of PCNS in ambient air of Ho Chi Minh City, Vietnam
Authors:   Faculty of Environmental Science, University of Science, District 05, Vietnam National University- Ho Chi Minh City, Viet Nam, Nguyen Minh Ngoc ,   Vietnam National University, Thu Duc City, Ho Chi Minh City, Vietnam, Nguyen Duy Dat ,   Faculty of Chemical and Food Technology, Ho Chi Minh City University of Technology and Education, Ho Chi Minh City, Vietnam, Ngo Thuan Thi ,   Vietnam National University, Thu Duc City, Ho Chi Minh City, Vietnam; Department of Environmental Engineering, International University, Thu Duc City, Ho Chi Minh City, Vietnam., To Hien Thi ,   Faculty of Environmental Science, University of Science, District 05, Vietnam National University- Ho Chi Minh City, Viet Nam; Vietnam National University, Thu Duc City, Ho Chi Minh City, Vietnam
Published: April 2023

Polychlorinated Naphthalenes (PCNs) were included as the new Persistent Organic Pollutants (POPs) under the Stockholm Convention and forced to terminate the production and use in any application due to their toxicity, bioaccumulation, persistence and adverse effects to the environment and humans. However, no study on the occurrence of PCNs in the environment in Vietnam has been conducted so far. Therefore, it is necessary to carry out an investigation on the presence of these pollutants in Vietnam. In this study, ambient air samples were collected at 5 different sites in the urban area of Ho Chi Minh City to investigate the occurrence of PCNs. Fourteen air samples (both gas and particulate phases) were collected using large volume samplers. Totally, 75 PCNs in gas and particulate phases were analyzed using HRGC/HRMS following isotope dilution method. Total concentrations of PCNs measured at five sites ranged from 60.4 pg/m3 to 264 pg/m3 (mean 134 pg/m3), which was significantly higher than those reported by similar studies around the world. The result also indicated that gaseous PCNs predominated in total atmospheric concentration (99.7 – 100%); while particulate PCNs only contributed minor faction. Based on the characteristics of the analyzed PCNs, the samples were divided into 2 groups, group 1 is characterized by TetraCN as the main contributor, while group 2 is dominated by low-chlorine homologues (1 to 3 chlorines). The results also revealed that the PCNs in the air samples in HCMC were mainly derived from evaporation of PCNs from products containing PCNs and combustion-related sources. However, evaporation of PCNs from products containing PCNs seemed to be the dominant source.
Investigating the effects of ingredient proportions on the texture of Vietnamese sausage using mixture experiment design
Authors:   Department of Food Technology, Faculty of Chemical Engineering, Ho Chi Minh University of Technology, VNU-HCM, Vietnam, Nguyen Hien Thi , Pham Thinh Huu ,   Department of Food Technology, Faculty of Chemical Engineering, Ho Chi Minh University of Technology, VNU-HCM, Vietnam, Nguyen Dzung Hoang ,   Department of Food Technology, Faculty of Chemical Engineering, Ho Chi Minh University of Technology, VNU-HCM, Vietnam
Published: April 2023

In this study, the effect of different ingredient proportions on the textural and hedonic characteristics of Vietnamese sausage was investigated. Vietnamese sausage is a widely popular traditional food of Vietnam, yet its characteristics are rarely investigated, especially the texture and hedonic properties. Vietnamese sausage’s texture was heavily influenced by three main ingredients: lean meat, lard and starch. In order to study the interactive effects of these three ingredients on texture as well as liking, eight samples with different proportions of these three main ingredients were prepared based on the mixture design approach. The textural characteristics (including hardness, cohesiveness, springiness, chewiness and gumminess) were determined using the texture profile analysis method, while a consumer panel (N = 70) evaluated their texture liking score. Surprisingly, all the texture characteristics were statistically significant difference. However, cohesiveness had a small variance between samples, signalling that this attribute is not important in describing the texture of Vietnamese sausage. To model the effect of ingredients, response surface regression with mixture model was carried out. The results showed that Scheffe’s special cubic model had a good fit for hardness (R2 = 0.946), chewiness (R2 = 0.902) while Scheffe’s quadratic model had a good fit for liking score (R2 = 0.967). The lean meat was found to be the ingredient with the largest effect on increasing the textural charactertistics as well as the liking score. Interestingly, upon inspecting the correlation between texture and liking score, the PCA map of both showed a similar structure. Finally, optimal values of the main ingredients for Vietnamese sausage formulations based on hedonic (> 6.5 liking score) were 4% - 8% starch, 70% - 76% lean meat and 18% - 26% lard. The analysis of consumers’ liking scores suggested that springiness is the main driver of liking for Vietnamese sausage products.
Application of blade element theory on horizontal axis wind turbines to research a novel dual rotor wind turbine
Authors:   Ho Chi Minh City University of Technology, Vietnam National University Ho Chi Minh City, Lê Huy Đăng , Nguyen Bao The ,   Ho Chi Minh City University of Technology, Vietnam National University Ho Chi Minh City
Published: April 2023

This research paper applies the blade element momentum theory on a horizontal axis wind turbine to study a 2-stage wind turbine with an independent rotating shaft, a type of small-scale wind turbine that has never been studied. The article also includes the Prandtl loss in the theory of the blade element momentum method to calculate the wind turbine so that the calculated power and efficiency are close to the actual efficiency instead of the consideration of ideal conditions. These theories have been around for a long time, but their applicability is still very high besides the use of modern computational tools such as computational fluid dynamics. Calculation results in the study are achieved by applying basic theories, then comparing with simulation results from Qblade software, a software that is commonly used in studies to calculate small and large-scale horizontal axis wind turbines and gives an error of less than 10%. This method is to ensure the objectivity and authenticity of the article. The proposed method in this study can be used to calculate various blade profiles of wind turbines. The paper aims to use the CL/CD ratio corresponding to a certain angle of attack as a specific case to optimize the calculation process, giving the problem can be automated.
Conative, Personality-based, Cognitive and Competence Approaches in the Semantic Sphere of the Individual’s Creativity
Authors:   Hryhorii Skovoroda University in Pereiaslav, Nabochuk Alexander
Published: April 2023

the aim of our article is to show conative, personality­based, cognitive and competence approaches in the semantic sphere of the individual’s creativity, to determine their characteristics, valuable and unique qualities.methods of the research. The following theoretical methods of the research were used to solve the tasks formulated in the article: the categorical method, structural and functional methods, the methods of the analysis, systematization, modeling, generalization. the results of the research. We think that leading to the development of the person’s creative imagination is metaphorical imagination (personal ap-proach). The latter is able to create new images of objects, ideas, meanings and emotional­sensual experiences, appealing to the imagination of the respondent who perceives. Metaphorical imagination is manifested as a person’s ability to independent creative metaphors, creatively interpret complex metaphors, cre-atively and originally apply existing metaphorical expressions depending on the context of a certain situation. Realizing the connection between the sensual and the rational, the construction of a creative metaphorical image activates the subject’s sensory­perceptual and emotional imagination on a creative level, thereby contributing to a new and deeper understanding of their essence.conclusions. We showed that psychological researches in a great degree emphasized such creative personality traits as productive ones, creative think-ing, the implementation of creative characteristics, transformative human acti­vity, the need for self­affirmation, material well­being, the transformation of the surrounding natural and social world, the implementation of doping strategies in the context of life achievements of the individual (a conative approach); in-tellectual activity, psychological flexibility, creative motivation, multivariate vi-sion of the surrounding world, originality, divergence; personal achievements (integrative approach); mental structures, mental representations, mental ex-perience, intellectual abilities – speed, originality, sensitivity, metaphoricality, formulation and original solution of a problem, actualization of the concept of a creative act (a cognitive approach); motivation to carry out creative activities, motivation to achieve success, situational self­actualization (a motivational ap-proach); a high level of professionalism, professional and creative semantics, creative explication of the situation, professional and creative social perception, creative aspects of communication (competence approach)
O Uso do Google Trends para Análise de Interesse por Informações sobre o Câncer no Brasil: Aspectos Teórico-Metodológicos
Authors: Lima Fernando Lopes Tavares de
Published: April 2023

A Internet tem sido utilizada como uma importante fonte de informação pela população e o uso disseminado do buscador Google para tal finalidade tem gerado um enorme banco de dados sobre o interesse da população em qualquer tema, incluindo o câncer. O Google Trends é utilizado para analisar tais dados, o que possibilita o monitoramento permanente dos interesses e comportamentos da população, e, assim, o habilita como importante ferramenta de análise para decisões em saúde pública. O presente artigo visa a apresentar uma orientação teórico-metodológica sobre a utilização do Google Trends para análise de dados, além de suas indicações e limitações de uso no âmbito da prevenção e controle do câncer no Brasil.
Territori intermedi del Lazio e Contratti di Fiume. Interpretazioni e strumenti per territori né metropolitani né interni
Authors: De Leo Daniela , Altamore Sara
Published: April 2023

A partire dagli apprendimenti derivanti dal lavoro su un Contratto di Fiume Lago e Costa, il saggio punta ad arricchire l'interpretazione dei "territori intermedi" con riferimento al contesto laziale analizzando le potenzialità dei CdF per l'inter- vento in aree sotto descritte e interpretate, oltre che poco presidiate dalle politiche territoriali.
Le cromie della città storica. Prefigurazione di nuovi scenari per la valorizzazione del centro storico della città di Giaveno
Authors: Gron Silvia , Tosco Cristiano
Published: April 2023

Un'esperienza di ricerca (2021) rivolta alla prefigurazione di scenari di valorizza- zione del centro storico di Giaveno (Torino), è l'occasione per valutare se, negli ultimi 30 anni, l'attività edilizia abbia garantito la sopravvivenza del genius loci. L'esposizione dei risultati riguarda il processo di trasformazione dell'aggregato storico e la descrizione evidenzia i principi e la metodologia adottata nel dichiara- re quali siano i contenuti che tengono saldo il rapporto fra storia e progetto.
Egidio Giannessi's contributions to cost accounting: The Kreislauf between Costs and Prices
Authors: Paolo Rigamonti Alessandro
Published: April 2023

Introduction: This study discusses the life and ideas of Egidio Giannessi, an im-portant Italian accounting theorist, and provides an in-depth critical analysis of The Kreislauf between Costs and Prices, a book that he wrote in 1958. Aim of the work: The research explores how the ideas in The Kreislauf are relevant for the discipline of cost accounting. The study also investigates the historical background and Giannessi's vision to identify the context in which The Kreislauf was developed. It aims to resume Giannessi's main statements by describing why the ideas are still valuable today. Methodological approach: The research is based on an interpretative approach. Main findings: The study provides a rationale to explain the absence from the in-ternational debate of Giannessi's ideas. The research investigates how The Kreis-lauf fits into the academic debate regarding its usefulness for practitioners of re-search in managerial accounting. Originality: The study proposes a link between the antitrust regulation on exces-sive pricing and the problem expressed in the book.
Tra trasformazioni normative e ricadute sociali. La figura del rider in Italia
Authors: Ferrigni Nicola , Rocchini Emilio
Published: April 2023

La recente proposta di direttiva dell'Unione europea che introduce una forma di presunzione di subordinazione del rapporto di lavoro di quanti svolgono la loro attività per il tramite di piatta-forme digitali ha riacceso i riflettori sul mondo dei rider e sulla necessità di regolamentare la diversificata platea dei lavoratori della gig economy. L'articolo presenta i risultati di una ricerca che combina l'approccio giuridico - attraverso l'analisi delle principali pronunce giurispruden-ziali e interventi legislativi - e l'approccio sociologico, che si traduce in una ricerca sul campo indirizzata ai rider delle principali piattaforme di food delivery. Dalla ricerca emerge come la resistenza degli intervistati rispetto all'idea di una subordinazione forzata sia motivata dalla non negozialità dei valori identitari alla base del proprio lavoro, che si traducono in una perfetta alchimia tra tempo e guadagno, e che chiamano in causa un necessario cambiamento, in primis culturale, funzionale a decretare il decisivo passaggio dal fear of changing al concern about changing.
Ccnl metalmeccanici 2021: il rinnovamento compiuto.. alla prova dell'applicazione
Authors: Alvino Ilario , Imberti Lucio , Maresca Arturo , Moia Sergio , Pero Luciano
Published: April 2023

Il saggio prende in esame i profili più rilevanti del rinnovo del contratto collettivo dei metal-meccanici del 2021, con particolare attenzione agli aspetti organizzativi e giuridici della riforma dell'inquadramento, nonché ai temi della formazione continua e dei diritti di partecipazione dei lavoratori. Uno specifico approfondimento viene, inoltre, dedicato - in virtù della possibilità di consultare la banca dati OCSEL (Osservatorio nazionale sulla Contrattazione di SEcondo Livello della Cisl) - alle tendenze della contrattazione aziendale nel periodo di ultrattività del ccnl 2016 e nel primo periodo di vigenza del ccnl 2021 attraverso un'analisi statistica e quantitativa degli accordi, nonché all'illustrazione di alcuni casi emblematici e di particolare rilievo. Il saggio si chiude con sintetiche riflessioni di carattere generale sulla portata del rinnovo contrattuale 2021 e, anche in ragione di tali riflessioni, pone problematicamente la questione della rile-vanza dei tempi e delle modalità di applicazione nelle singole realtà aziendali del ccnl medesi-mo.
The error role in risk perception
Authors: Corposanto Cleto , Molinari Beba
Published: April 2023

After some time since the onset of the Covid19 pandemic, we believe it is now possible to reflect on how the global response to the worldwide spread of the virus has been organized, and at the same time reflect on the emergency approach that has characterized the responses on the health front but also the public communication of the same pandemic. The hypothesis around which we work is that the term of emergency itself is not appropriate except to designate a sit-uation that is strictly related to a reductionist approach to understanding and explaining phenomena. An event becomes an emergency only if we reason in terms of a linear explanation, avoiding paying attention to the real complexity of the phenomena, with a comprehensive look at systemic interrelationships. In this perspective, Horton correctly proposed the term syndemic to characterize the set of events related to Covid19 (Horton, 2020). Because the unexpected, which is experienced and managed as an emergency, arises from an obvious interpretative error if the problem is not addressed with a systemic logic. And it can perhaps also be hypothe-sized that as such - that is, as unexpected and emerging - any phenomenon legitimizes proce-dural and communicative errors, thus exonerating in some way whoever is responsible for facing them.
The Pandemic and Sustainable Peace. A combination yet to be understood
Authors: Iannone Roberta , Gurashi Romina
Published: April 2023

This essay aims to verify the existing combination of low levels of sustainable peace and the SARS-CoV-2 pandemic. The hypothesis we want to support is that the aforementioned panemic wouldn't have become a world crisis had there been greater investments in social and environmental issues, which are the sources of sustainable peace. The applied methodology is preceded by a brief description of the different meanings of and the interdependencies between sustainable development and peace, a reflection on the main reports, both national (Italian Min-istry of Health, Italian National Statistical Institute) and international (UN, UNPD, IMF, WHO, IEP) and a quantitative supplementary analysis of their guidelines insofar as pandemic-related sustainability and sustainable peace are concerned. Our goal is to prove how much needed and no longer deferrable is a reading able to reconcile factors that are different from each other when it comes to their nature and content. Such factors are environmental pollution, climate change, cultural and structural violence, inequalities within individual States and be-tween States.
Minimizing extinction risk through genetic rescue
Authors:   Ohio State Univ., Columbus, Ohio, USA, Waite T. A. , Vucetich J. A. ,   Michigan Technological Univ., Houghton, Michigan, USA, Saurer T. ,   Ohio State Univ., Columbus, Ohio, USA, Kroninger M. ,   Ohio State Univ., Columbus, Ohio, USA, Vaughn E. ,   Ohio State Univ., Columbus, Ohio, USA, Field K. ,   Ohio State Univ., Columbus, Ohio, USA, Ibargüen S. ,   Ohio State Univ., Columbus, Ohio, USA
Published: April 2023

According to the genetic rescue hypothesis, immigrants can improve population persistence through their genetic contribution alone. We investigate the potential for such rescue using small, inbred laboratory populations of the bean beetle (Callosobruchus maculatus). We ask how many migrants per generation (MPG) are needed to minimize the genetic component of extinction risk. During Phase 1, population size was made to fluctuate between 6 and 60 (for 10 generations). During this phase, we manipulated the number of MPG, replacing 0, 1, 3, or 5 females every generation with immigrant females. During Phase 2, we simply set an upper limit on population size (.10). Compared with the 0-MPG treatment, the other treatments were equivalently effective at improving reproductive success and reducing extinction risk. A single MPG was sufficient for genetic rescue, apparently because effective migration rate was inflated dramatically during generations when population size was small. An analysis of quasi-extinction suggests that replicate populations in the 1-MPG treatment benefited from initial purging of inbreeding depression. Populations in this treatment performed so well apparently because they received the dual benefit of purging followed by genetic infusion. Our results suggest the need for further evaluation of alternative schemes for genetic rescue.
Land snail diversity in a threatened limestone district near Istanbul, Turkey
Authors:   Carnegie Museum of Natural History, Pittsburgh, PA, USA, Örstan A. , Pearce T. A. ,   Carnegie Museum of Natural History, Pittsburgh, PA, USA, Welter-Schultes F. ,   Zoologisches Inst., Goettingen, Germany
Published: April 2023

The limestone meadows located to the north­-northwest of Istanbul, Turkey, are in danger of being overrun by the rapidly expanding city. Past surveys showed that these habitats harbor rare plant species, including endemics to Turkey. To further evaluate the conservation value of these habitats, especially in terms of the often neglected invertebrates, one limestone area to the north of Küçükçekmece Lake and surrounding Sazlidere Dam was surveyed for land snails. Our findings strengthen the case for the protection of these unique habitats. Twenty­-four species of land snails were identified in the survey area. Of these, 21 are native to Turkey, including three whose type location is Istanbul. In addition, two species that are at or near the limits of their ranges are considered to represent peripheral populations that may be especially worth conserving. Although the area surrounding Sazlidere Dam is under protection, the other limestone habitats are severely threatened by ongoing development.
Improved Detection and Analysis of Wheat Spikes U sing Multi-Stage Convolutional Neural Network
Authors: Batin M A , Islam Muhaiminul , Hasan Md Mehedi , Miklavcic Stanley J
Published: April 2023

High throughput plant phenotyping is the advanced scientific approach for rapid phenotyping of plant traits, especially high consumable grains or crops, which is designed to process a high volume of data in a short time for plant breeders and cultivars to utilize. Detection and counting of crop traits such as plants, fruits, wheat or rice spikes, sorghum head, and plant diseases is more advanced research in this field, where real-world data are collected using aerial and land-based imaging platforms equipped with a variety of geospatial sensors, and their statistical analysis is conducted using Artificial Intelligence (AI) and Deep Learning-based solutions. In this paper, we contributed to solving such a challenge of phenotyping by detecting and counting wheat spikes from land-based imaging by applying a Region-based Convolutional Neural Network (CNN) model. Our method employs the use of CNN to extract features from the imaging platform and the learning model is trained to detect and count wheat spikes in field images based on these extracted features. Using the publicly available SPIKE dataset to train and test our model, our proposed method achieved 98% average precision and 91% average F1 score on the test set. Our results show a significant improvement of 2.9% and 11.2% in detection accuracy as well as 1% and 3% in average precision metric over state-of-the-art Faster Regionbased Convolutional Neural Network (Faster-RCNN), and RetinaNet, respectively, and have the potential to significantly benefit plant breeders by facilitating the selection of wheat varieties with high yields.
DUJASE Vol. 7 (2) 21-30, 2022 (July)
DAMPAK PROFITABILITAS DAN LIKUIDITAS TERHADAP HARGA SAHAM PADA PERUSAHAAN MAKANAN DAN MINUMAN DI INDONESIA
Authors: Idris Ahmad
Published: April 2023

Tujuan penelitian ini untuk mengetahui pengaruh profitabilitas dan likuiditas terhadap harga saham. Profitabilitas menggunakan Return on Asset (ROA), dan likuiditas menggunakan Current Ratio (CR) sedangkan harga saham menggunakan harga penutupan. Populasi adalah perusahaan makanan dan minuman terdaftar di Bursa Efek Indonesia sebanyak 10 perusahaan. Teknik pengambilan sampel menggunakan purposive sampling diperlukan sebanyak 60 laporan keuangan tahun 2014-2019. Analisis menggunakan analisis regresi data panel. Hasil penelitian menjelaskan Return on Asset berpengaruh positif terhadap harga saham, dan Current Ratio tidak berpengaruh signifikan terhadap harga saham. Secara simultan diperoleh Return on Assets, dan Current Asset berpengaruh terhadap harga saham perusahaan makanan dan minuman di Indonesia. Kata kunci: current ratio, harga saham, return on asset The purpose of this study was to determine the effect of profitability and liquidity on stock prices. Profitability uses Return on Assets (ROA), and liquidity uses Current Ratio (CR) while stock prices use closing prices. The population is 10 food and beverage companies listed on the Indonesia Stock Exchange. The sampling technique used purposive sampling is 60 financial reports for the years 2014-2019. Analysis using panel data regression analysis. The results of the study explain that Return on Assets has a positive effect on stock prices, and the Current Ratio has no significant effect on stock prices. Simultaneously, Return on Assets is obtained, and Current Asset has an effect on stock prices of food and beverage companies in Indonesia.Keywords: current ratio, return on asset, stock prices
Penerapan model pembelajaran untuk mengembangkan berpikir kritis siswa bagi guru sekolah dasar
Authors: Ni'mah Nurun , Bulkani  , Estimurti Endang Sri , Setyawan Dedy , Riadin Agung
Published: April 2023

Peningkatan kualitas mengajar guru adalah hal terpenting dalam dunia Pendidikan mengingat guru adalah ujung tombak pelaksanaan pendidikan di sekolah. Selain itu pemerataan kualitas Pendidikan juga menjadi perhatian tersendiri pada kabupaten berkembang seperti di Kabupaten Barito Utara. Sejalan dengan hal tersebut, salah satu sekolah dasar swasta di Barito Utara yaitu SD Muhammadiyah memiliki komitmen dalam peningkatan kualitas mengajar guru agar guru di sekolah tersebut dapat mengembangkan kemampuan berpikir kritis siswa di daerahnya. Tujuan kegiatan ini adalah untuk mengembangkan kompetensi guru-guru daerah dalam hal pengajaran. Adapun metode yang digunakan adalah Participatory Action Research (PAR) dalam bentuk pelatihan dengan tahapan yaitu: identifikasi, Pretest, pelaksanaan pelatihan dan Posttest. Dampak positif dirasakan dari pelatihan ini. Hal ini karena kegiatan ini dapat membantu kesulitan serta memenuhi kebutuhan peserta dalam hal penerapan model pembelajaran untuk mengembangkan kemampuan berpikir kritis siswa. Selanjutnya, kegiatan sosialisasi dan pelatihan ini juga mencapai target yang sudah disusun sebelumnya yaitu para guru mampu meningkatkan dan memperkaya pengetahuan mereka model pembelajaran, kemampuan berpikir kritis siswa serta cara pengembangan instrument berpikir kritis siswa.
Transparansi arus kas rumah tangga keluarga menggunakan aplikasi expense track
Authors: Putra Hery Astika , Halpiah Halpiah , Rosita Rosita
Published: April 2023

Kegiatan PKM dilatarbelakangi permasalahan mitra belum bisa mengelola keuangan rumah tangga baik secara akuntansi maupun manajemen keuangan. Hal ini sering menjadi pemicu kecurigaan pasangan dalam penggunaan uang. Tujuan PKM agar mitra meningkatkan literasinya dalam pengelolaan keuangan berlandaskan pengetahuan akuntansi dan manajemen keuangan dengan membuat pencatatan pengeluaran harian secara manual atau menggunakan aplikasi expense track agar uang yang keluar bisa ditelusuri hingga tercapai transparansi dalam pengelolaan keuangan. Pelaksanaan PKM menggunakan 4 fase yaitu fase analisis masalah dengan metode observasi dan wawancara dilanjutkan fase perancangan kegiatan dengan metode FGD kemudian fase pelaksanaan dengan metode ceramah, tanya jawab, eksperimen dan fase evaluasi transformasi serta evaluasi out put. Dalam kegiatan diketahui sebanyak 43% memahami pengelolaan keuangan, 9%  mengerti tentang arus kas rumah tangga,  100% merespon dan mengikuti kegiatan, sedangkan dari evaluasi output dapat disimpulkan bahwa peserta dapat  membuat jurnal arus kas rumah tangga secara manual sebanyak  52%, mampu membuat jurnal arus kas rumah tangga menggunakan aplikasi expense track sebanyak 35%, minat dalam membuat jurnal arus kas rumah tangga baik secara manual maupun  menggunakan aplikasi expense track sebanyak 87% . Bentuk tindak lanjutnya memonitoring peserta melalui ketua pengajian agar dapat di bimbing secara berkelanjutan hingga memiliki kesadaran mau mengelola uangnya dengan bijak sekecil apapun nominalnya.
Bagaimana panti asuhan bertahan pada masa pandemi COVID-19?
Authors: Irwani Muhammad Fakhriza , Fadhilah Hasna Azmi
Published: April 2023

Merujuk data Kementerian Sosial RI, tercatat sekitar 30 ribu anak menjadi yatim piatu akibat COVID-19. Sebagian dari mereka akhirnya ditempatkan di panti asuhan. Namun, dalam memenuhi keperluan penghuni, panti menghadapi banyak kendala, salah satunya berkaitan dengan anggaran yang terbatas dan penghuni panti yang masih kesulitan dalam mengembangkan potensi diri karena tidak maksimalnya pembelajaran daring saat pandemi. Sehingga, yayasan perlu memutar otak untuk mengakomodasi kebutuhan finansial sekaligus kesehatan mental, termasuk pemenuhan akademik bagi para penghuninya. Melihat permasalahan yang ada, penulis kemudian mencoba membantu Panti Asuhan bertahan dengan menyelenggarakan pelatihan dan kursus intensif bagi anak-anak di sana dan membantu pemberdayaan unit usaha yang dikelola oleh panti. Metode pelaksanaan kegiatan yang dilaksanakan dibagi menjadi 3 tahapan yakni: tahap koordinasi, tahap persiapan, dan tahap pelaksanaan. Tahap pelaksanaan difokuskan pada penggalian potensi anak dan pendampingan psikologis. Sedangkan untuk optimalisasi unit usaha, diberikan pemahaman mengenai pemaksimalan promosi dan penjualan. Artikel ini menggambarkan bagaimana penulis mendampingi panti asuhan untuk bertahan saat pandemi dengan jangka waktu dari minggu terakhir Bulan Februari serta minggu pertama dan kedua di Bulan Maret 2021 dengan pelaksanaan bertempat di Panti Asuhan Sentosa Kota Banjarmasin. Dari pendampingan yatim piatu yang telah dilakukan, anak-anak menjadi lebih stabil emosionalnya, dan mampu mengenali potensi diri lebih baik. Sedangkan unit usaha panti asuhan dapat memaksimalkan promosi dan tingkat penjualan mereka.
Pendampingan self-management diabetes dan hipertensi bagi lansia melalui edukasi dan games
Authors: Pahriyani Ani , Sulistaningsih Endang , Siregar Mirawati
Published: April 2023

Kegiatan Program Kemitraan Masyarakat ini bertemakan Penguatan Self-Management Diabetes dan Hipertensi melalui edukasi dan Games di Muhammadiyah Senior Care Rumah Sakit Islam Jakarta Sukapura dengan sasaran lansia tergabung dalam Muhammadiyah Senior Care (MSC) RS Islam Jakarta Sukapura Jakarta Utara. Tema ini dipilih karena salah satu cara yang efektif dalam penguatan self-management untuk penyakit menahun yang banyak diderita oleh para lansia adalah pengobatan secara paliatif yang diharapkan dapat meningkatkan kualitas hidup pasien. Metode penyuluhan ini menggunakan metode Asset Based Communities Development (ABCD) melalui edukasi dan permainan yang dapat merangsang otak dan meningkatkan semangat para lansia serta menambah pengetahuan pasien. Materi edukasi disampaikan langsung oleh dosen farmasi dalam tim pengabdian ini dan kompetensi baik dari sisi keilmuan maupun dasar-dasar penyuluhan yang disampaikan oleh dosen yang sekaligus praktisi kesehatan di Rumah Sakit. Hasil dari pelaksanaan kegiatan ini dapat dilihat dengan antusiasme peserta dalam kegiatan ini serta didukung dari hasil penyebaran kuesioner pengetahuan self-management diabetes dan hipertensi setelah kegiatan berlangsung diperoleh 52% peserta pengetahuannya dengan kategori baik, 32% kategori cukup dan 16% kategori kurang. Simpulan dari kegiatan ini bahwa penguatan self-management diabetes dan hipertensi memiliki kemanfaatan bagi masyarakat warga Muhammadiyah Senior Care RSIJ Sukapura.
Novel suspension retroviral packaging cells generated by transposition using transposase encoding mRNA advance vector yields and enable production in bioreactors
Authors: van Heuvel Yasemin , Schatz Stefanie , Hein Marc , Dogra Tanya , Kazenmaier Daniel , Tschorn Natalie , Genzel Yvonne , Stitz Jörn
Published: April 2023

To date, the establishment of high-titer stable viral packaging cells (VPCs) at large scale for gene therapeutic applications is very time- and cost-intensive. Here we report the establishment of three human suspension 293-F-derived ecotropic MLV-based VPCs. The classic stable transfection of an EGFP-expressing transfer vector resulted in a polyclonal VPC pool that facilitated cultivation in shake flasks of 100 mL volumes and yielded high functional titers of more than 1 × 106 transducing units/mL (TU/mL). When the transfer vector was flanked by transposon terminal inverted repeats (TIRs) and upon co-transfection of a plasmid encoding for the transposase, productivities could be slightly elevated to more than 3 × 106 TU/mL. In contrast and using mRNA encoding for the transposase, as a proof of concept, productivities were drastically improved by more than ten-fold exceeding 5 × 107 TU/mL. In addition, these VPC pools were generated within only 3 weeks. The production volume was successfully scaled up to 500 mL employing a stirred-tank bioreactor (STR). We anticipate that the stable transposition of transfer vectors employing transposase transcripts will be of utility for the future establishment of high-yield VPCs producing pseudotype vector particles with a broader host tropism on a large scale.
Preparation, modification, and clinical application of porous tantalum scaffolds
Authors: Wang Xinyi , Zhou Ke , Li Yada , Xie Hui , Wang Benjie
Published: April 2023

Porous tantalum (Ta) implants have been developed and clinically applied as high-quality implant biomaterials in the orthopedics field because of their excellent corrosion resistance, biocompatibility, osteointegration, and bone conductivity. Porous Ta allows fine bone ingrowth and new bone formation through the inner space because of its high porosity and interconnected pore structure. It contributes to rapid bone integration and long-term stability of osseointegrated implants. Porous Ta has excellent wetting properties and high surface energy, which facilitate the adhesion, proliferation, and mineralization of osteoblasts. Moreover, porous Ta is superior to classical metallic materials in avoiding the stress shielding effect, minimizing the loss of marginal bone, and improving primary stability because of its low elastic modulus and high friction coefficient. Accordingly, the excellent biological and mechanical properties of porous Ta are primarily responsible for its rising clinical translation trend. Over the past 2 decades, advanced fabrication strategies such as emerging manufacturing technologies, surface modification techniques, and patient-oriented designs have remarkably influenced the microstructural characteristic, bioactive performance, and clinical indications of porous Ta scaffolds. The present review offers an overview of the fabrication methods, modification techniques, and orthopedic applications of porous Ta implants.
Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition
Authors: Li Yueheng , Yang Zhengyan , Cai Ting , Jiang Dan , Luo Jun , Zhou Zhi
Published: April 2023

Objective

To compare the differences in salivary metabolites between caries-active and caries-free children in the mixed dentition, and explore their correlation with caries status.

Methods

The study involved 20 children (aged 8–9 years) in the mixed dentition, including 10 caries-active (aged 8.6 ± 0.49years) and 10 caries-free children(aged 8.5 ± 0.5years), with a male/female ratio of 1:1. The saliva samples were collected from all children. Metabolite extraction, LC-MS/MS-based untargeted metabolomics, qualitative and semi-quantitative analysis and bioinformatics analysis were performed to identify differential metabolites between the two sample groups. The differential metabolites identified were further analyzed in an attempt to find their correlations with caries status.

Results

In the positive ion mode, a total of 1606 molecular features were detected in the samples of the two groups, 189 of which were differential metabolites when comparing the caries-active group with the caries-free group, including 104 up-regulated and 85 down-regulated metabolites. In the negative ion mode, a total of 532 molecular features were detected in the samples of two groups, 70 of which were differential metabolites when comparing the caries-active group with the caries-free group, including 37 up-regulated and 33 down-regulated metabolites. In the positive ion mode, two of the top 5 up-regulated differential metabolites were found in and annotated to specific metabolic pathways, whereas in the negative ion mode, only one of the top 5 up-regulated differential metabolites was found in and annotated to specific metabolic pathways. In both the positive and negative ion modes, the top 5 down-regulated differential metabolites were both annotated to the metabolic pathways. KEGG pathway enrichment analysis of differential metabolites showed that histamine and arachidonic acid identified in the positive ion mode, as well as succinate and L-histidine identified in the negative ion mode were enriched in the top 3 significantly altered pathways.

Conclusion

The enriched differential metabolites including histamine, L-histidine and succinate were correlated with the presence of dental caries, but their role in the caries process needs to be further investigated.
Microbiome and metabolome associated with white spot lesions in patients treated with clear aligners
Authors: Song Zhixin , Fang Shishu , Guo Tao , Wen Yi , Liu Qian , Jin Zuolin
Published: April 2023

White spot lesions (WSLs) have long been a noteworthy complication during orthodontic treatment. Recently, an increasing number of orthodontists have found that adolescents undergoing orthodontic treatment with clear aligners are at a higher risk of developing WSLs. The oral microbiota and metabolites are considered the etiologic and regulatory factors of WSLs, but the specific impact of clear aligners on the oral microbiota and metabolites is unknown. This study investigated the differences in the salivary microbiome and metabolome between adolescents with and without WSLs treated with clear aligners. Fifty-five adolescents (aged 11-18) with Invisalign appliances, 27 with and 28 without WSLs, were included. Saliva samples were analyzed using 16S rRNA gene sequencing and ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS); the data were further integrated for Spearman correlation analysis. The relative abundances of 14 taxa, including Actinobacteria, Actinomycetales, Rothia, Micrococcaceae, Subdoligranulum, Capnocytophaga, Azospira, Olsenella, Lachnoanaerobaculum, and Abiotrophia, were significantly higher in the WSL group than in the control group. Metabolomic analysis identified 27 potential biomarkers, and most were amino acids, including proline and glycine. The metabolites were implicated in 6 metabolic pathways, including alanine, aspartate and glutamate metabolism; glycine, serine and threonine metabolism; and aminoacyl-tRNA biosynthesis. There was a correlation between the salivary microbial and metabolomic datasets, reflecting the impact of clear aligners on the metabolic activity of the oral flora. A concordant increase in the levels of Lachnoanaerobaculum, Rothia, Subdoligranulum and some amino acids had predictive value for WSL development. In summary, when adolescents undergo long-term clear aligner therapy with poor oral hygiene habits, clear aligners can disrupt the balance of the oral microecosystem and lead to oral microbiota dysbiosis, thereby increasing the risk of developing WSLs. Our findings might contribute to the understanding of the pathogenesis of WSLs and provide candidate biomarkers for the diagnosis and treatment of WSLs associated with clear aligners.
Emotional complexity of fan-controlled comments: Affective labor of fans of high-popularity Chinese stars
Authors: Wei Yuruo
Published: April 2023

In China, fan participation in media production is becoming more mainstream and diverse, and fan groups themselves are developing perceptible emotional attributes; thus, studies on affective labor involving fans are gradually increasing in number. Fan-controlled comments are a feature of fan culture that has received much attention due to their rapid growth and influence. This study uses sentiment analysis and keyword analysis to examine the main types of “emotions” felt by today's fans of highly popular stars and classifies them into four categories: idols, fan communities, the self, and the outside world. Both positive and negative emotions coexist. The study found that fans engage in this kind of obligatory affective labor, creating second-hand exchanges for personal spiritual enrichment, and focusing more on building and expressing emotions. In addition, as affective laborers, they gain a sense of belonging to a fan community and form group symbols because of their shared emotions and concerns. Throughout the process of controlling comments, the time and energy of the fan groups are consumed, their emotions are controlled, and their behavior is restrained; however, the immediate purpose they want to achieve is not achieved. What seems to be an active choice is a trap of alienated labor, bound, and controlled by forces.