bluuebunny/crossref_metadata_2025 huggingface dataset:
The Prognostic Significance of Body Mass Index and Metabolic Parameter Variabilities in Predialysis CKD: A Nationwide Observational Cohort Study
Authors: Park Sehoon , Cho Semin , Lee Soojin , Kim Yaerim , Park Sanghyun , Kim Yong Chul , Han Seung Seok , Lee Hajeong , Lee Jung Pyo , Joo Kwon Wook , Lim Chun Soo , Kim Yon Su , Han Kyungdo , Kim Dong Ki
Published: August 2021

Significance statement

The prognostic significance of variabilities in body mass index (BMI) or metabolic parameters in patients with CKD is uncertain. In this observational cohort study of 84,636 patients with predialysis CKD in South Korea, the authors analyzed the association between variability of BMI or various metabolic parameters and risks of all-cause mortality and incident myocardial infarction, stroke, and requirement for KRT. They found that elevated variability in BMI or certain metabolic parameters was associated with higher risks of adverse outcomes, independent of baseline metabolic status. These findings may encourage clinicians in the nephrology field to carefully assess not only baseline BMI or metabolic status in patients with CKD, but also the fluctuating status of metabolic parameters, due to their potential prognostic significance in such patients.

Background

The association between variabilities in body mass index (BMI) or metabolic parameters and prognosis of patients with CKD has rarely been studied.

Methods

In this retrospective observational study on the basis of South Korea’s national health screening database, we identified individuals who received ≥3 health screenings, including those with persistent predialysis CKD (eGFR <60 ml/min per 1.73 m2 or dipstick albuminuria ≥1). The study exposure was variability in BMI or metabolic parameters until baseline assessment, calculated as the variation independent of the mean and stratified into quartiles (with Q4 the highest quartile and Q1 the lowest). We used Cox regression adjusted for various clinical characteristics to analyze risks of all-cause mortality and incident myocardial infarction, stroke, and KRT.

Results

The study included 84,636 patients with predialysis CKD. Comparing Q4 versus Q1, higher BMI variability was significantly associated with higher risks of all-cause mortality (hazard ratio [HR], 1.66; 95% confidence interval [95% CI], 1.53 to 1.81), P [for trend] <0.001), KRT (HR, 1.20; 95% CI, 1.09 to 1.33; P<0.001), myocardial infarction (HR, 1.19; 95% CI, 1.05 to 1.36, P=0.003), and stroke (HR, 1.19; 95% CI, 1.07 to 1.33, P=0.01). The results were similar in the subgroups divided according to positive or negative trends in BMI during the exposure assessment period. Variabilities in certain metabolic syndrome components (e.g., fasting blood glucose) also were significantly associated with prognosis of patients with predialysis CKD. Those with a higher number of metabolic syndrome components with high variability had a worse prognosis.

Conclusions

Higher variabilities in BMI and certain metabolic syndrome components are significantly associated with a worse prognosis in patients with predialysis CKD.
Use of the Federal Reserve's repo operations and changes in dealer balance sheets
Authors: Carlson Mark , Saravay Zack , Tian Mary
Published: August 2021

Before the 2008 financial crisis, the Federal Reserve (Fed) regularly conducted repurchase agreements (repos) in a fairly modest size with primary dealers to adjust the supply of reserves in the banking system and to keep the federal funds rate at the target set by the FOMC. During the economic downturn that followed the financial crisis, the Fed engaged in large scale asset purchases in order to provide additional monetary accommodation, and those purchases significantly increased the supply of reserves and eliminated the need for the Fed to engage in repo operations to increase reserves in the system.
IMC STAINING FOR PARAFFIN SECTIONS v1
Authors: H. Kaestner Lab Klaus , Shapira Suzanne
Published: August 2021

Imaging mass cytometry (IMC) is a multiplexed imaging method that allows samples to be probed with up to forty antibodies at one time. This enables visualization of multiple cell types simultaneously in the native tissue microenvironment. For example, IMC can be applied to study the interactions between endocrine cells and the immune system in pancreata from donors diagnosed with type 1 diabetes. This protocol describes a technique for IMC staining of paraffin sections with a defined antibody panel to identify immune, islet, endocrine, and stromal cell types of the pancreas.
Protocol of the competitive audit for designing and developing the National Edition of Aldo Moro's works v2
Authors: Barzaghi Sebastian
Published: August 2021

This work aims to define a series of reference models that would serve as a guide to the design and development of the National Edition of Aldo Moro's works. These models have been defined through a benchmarking process that is organized as follows: content analysis on a sample of 30 digital editions, evaluated on the basis of certain criteria defined in Sahle 2014; processing of the data gathered as a result of the content analysis, so as to extract the relevant information, and visualize it; review of the data processing results and consideration of the models that can be used as reference. The digital editions that meet the quality criteria taken into consideration are equipped with the following characteristics: their audience is composed of both domain experts and generic users; their documentation is rich and accurate; their content is described by a complete set of metadata; they and their single parts are citable and uniquely identifiable; their data model is geared towards interoperability and interlinking between its contents and the relevant resources already existing on the Web; they use visualization and storytelling tools so as to convey information intuitively; their information architecture is well-structured and easily navigated; their data and contents can be downloaded in many different formats; they take advantage of Open Source software and tools; finally, their contents are open and accessible to anyone.
Protocol forsgRNA in vitro transcription and screening for effective SaCas9 RNP complex cleavage assay v1
Authors: Gomaa Fatma
Published: August 2021

Developing transfection protocol for Bodo saltans, using SaCas9/sgRNA ribonucleoprotein (RNP) complex in conjunction with DNA repair template to disrupt the Paraflagellar rod 2 gene (BsPFR2) and increase the efficiency of targeted homologous recombination when a repair template DNA is provided. The exogenous repair template is double stranded DNA and it consists of eGFP fused with the drug selection gene nptII/neo and flanked by 500 bp of the untranslated regions (UTRs) upstream and downstream of the targeted BsPFR2 as homologous repair arms.
PSYCHOLOGICAL PECULIARITIES OF OLDER PRESCHOOL-AGE ORPHANS’ INTERPERSONAL RELATIONS
Authors: Baranauskiene I. , Kovalenko A. B.
Published: August 2021

The article presents the research on the characteristics of older preschool-age orphans’ interpersonal relationships. It reveals differences between the functioning of the sphere of orphans’ interpersonal relations and that of children brought up in families. Orphans show higher interest in adults, indicating that orphans’ need in adults’ attention is not satisfied. The main motives for communication with adults in families are mutual interactions and cognitive needs, while the dominant motive of orphan children is searching for attention and kindness.
Orphans show increased inclination to conflicts, cause for which are every-day issues and the struggle for adults’ attention and friendliness. The main cause of conflicts characteristic for family-raised children is their selfaffirmation in games.
Orphans are less and less likely to express their own emotions when communicating. They rarely turn to their partners for some advice, support, and sharing of experiences, unlike children in families. Orphaned children feel indifference in relationships with peers.
Differences were found between orphaned children and family-raised children as for well-being of relationships: orphans’ well-being is quite low, while family-raised children’s well-being is high.
Orphaned children, due to problems in interpersonal relationships with adults and peers, have some deviations in the most important psychological formations: distortion of self image, delayed formation of subjective attitude to oneself, as well as slow and abnormal development of activity, which may further negative affect their psychological well-being.
USING R FOR PSYCHOLOGICAL RESEARCH: A TUTORIAL OF BASIC METHODS
Authors: Vinogradov A. G.
Published: August 2021

The article belongs to a special modern genre of scholar publications, so-called tutorials – articles devoted to the application of the latest methods of design, modeling or analysis in an accessible format in order to disseminate best practices. The article acquaints Ukrainian psychologists with the basics of using the R programming language to the analysis of empirical research data. The article discusses the current state of world psychology in connection with the Crisis of Confidence, which arose due to the low reproducibility of empirical research. This problem is caused by poor quality of psychological measurement tools, insufficient attention to adequate sample planning, typical statistical hypothesis testing practices, and so-called “questionable research practices.” The tutorial demonstrates methods for determining the sample size depending on the expected magnitude of the effect size and desired statistical power, performing basic variable transformations and statistical analysis of psychological research data using language and environment R. The tutorial presents minimal system of R functions required to carry out: modern analysis of reliability of measurement scales, sample size calculation, point and interval estimation of effect size for four the most widespread in psychology designs for the analysis of two variables’ interdependence. These typical problems include finding the differences between the means and variances in two or more samples, correlations between continuous and categorical variables. Practical information on data preparation, import, basic transformations, and application of basic statistical methods in the cloud version of RStudio is provided.
FEATURES OF PERSONAL WELL-BEING OF MILITARIES WHO WERE IN THE ATO ZONE
Authors: Danylchenko T. V.
Published: August 2021

In Ukrainian military psychology, the emphasis is on mitigating the effects of post-traumatic stress on servicemen. Little attention is paid to the prevention and study of the positive functioning of combatants. In the study of personal well-being of servicemen, its psychological aspect is presented, social and emotional well-being was less studied. Personal well-being is seen as an integral personal formation that provides a person with the conditions for positive actions and experiencing a successful relationship. The results of an empirical study of the personal wellbeing of ATO participants are presented (N = 107). It is shown that all components of personal well-being: emotional, social and psychological well-being have a higher level in servicemen who were in the antiterrorist operation zone, compared to non-military men. Satisfaction with life of anti-terrorist operation participants is more related to their own assessment of achievements, personal characteristics and actions, while non-combatants’ satisfaction with life depends more on assessments of the social environment. Achieving individual goals is more important for non-military. The goals of servicemen are more socially oriented, they feel the social value of their activities, and therefore see more meaning in their lives. The criterion for assessing the personal success of the participants of the anti-terrorist operation is only their own feelings; they tend to pay less attention to social approval. The obtained data are relevant for the Chernihiv region.
Economic Losses of the Russian Budgetary System
Authors: Karaseva Marina V.
Published: August 2021

The article analyzes a new legal trend, the essence of which is to consider property relations as a single complex, whereby the boundaries of certain segments of property and legal regulation complement and replace each other. The analysis of jurisprudence and, above all, case law and justice gives examples of such phenomena.
The article analyzes the rulings of the Constitutional Court of the Russian Federation, which show a connection between tax and civil law. First of all, this resolution of the Russian Constitutional Court of December 08, 2017 No. 39-П, which was to some extent a turning point, because it introduced the possibility of the subsidy of state coercion and confirmed the new content of delita liability, provided for by Article 1064 of the Russian Civil Code. Delicate liability began to transform and became not only a means of reparations to the holder of absolute right, but also an expanded reimbursement of purely economic losses. The latter are defined as physical damage not resulting from physical injury to a person or property. From these positions, the article analyzes the Rulings of the Russian Constitutional Court of 05.03.2019 No. 14-П and from 02.07 2020 No. 32-П.
The two above-mentioned rulings are united by the fact that the possibility of recovering purely economic losses under Article 1064 of the Russian Civil Code in these decisions is assumed, i.e., it indirectly stems from the content of the decision. In the article the author concludes that the widespread use of tort liability situations involving public relations shows that, thanks to the expansion of its content, it tends to go beyond civil law and the article by the institution of inter-industry.
Conducting Psychological Examinations for Citizens in Possession of Weapons: Strengthening State Control Over Circulation of Weapons
Authors: Bokov Sergey N. , Zhdanov Maxim I.
Published: August 2021

In the article, in connection with the introduction of amendments to the federal legislation, specific issues regarding the conducting of a psychological survey of citizens gun owners and candidates for gun ownership are considered. A battery of psychodiagnostic techniques that can be used in the course of a psychological examination (progressive matrices of J. Raven, a questionnaire of the Level of subjective control, and a method for diagnosing frustration tolerance from Rosenzweig, Minnesota Multidisciplinary Personality Questionnaire) is proposed and justified, as is an algorithm for conducting psychodiagnostic research. Furthermore, a proposal to include in the psychological examination, a psychological analysis of social networks (provided that the subject is a member of their group) has been made. The possible participation in the psychological survey gun owners and candidates for gun ownership psychologists of Rosgvardiya are justified and the specific form of their participation in the survey is indicated.
Esophageal inlet patch: Demographic and endoscopic characteristics of patients and review of the literature
Authors: KÖKER İbrahim , ŞAHİN Nurhan
Published: August 2021

Background and Aims: An esophageal inlet patch is crucial in swallowing difficulty, laryngopharyngeal reflux symptoms, and rarely in the etiology of proximal esophagus adenocarcinoma. We aimed to evaluate the endoscopic and demographic features of patients with esophageal inlet patch during endoscopic evaluation and compare them with those of the literature. Material and Method: Between January 2017 and January 2021, we evaluated the age, gender ratio, inlet patch size, and number along with the other endoscopic findings in patients with proximal esophageal inlet patch. Results: Overall, 53 patients (women, 36 (68%); mean age, 46.3 ± 15.8 years; range, 19–83 years) were included the study. Only 13 patients (24.5%) had specific symptoms of esophageal inlet patch. The median esophageal inlet patch size was 7.0 mm in women (range, 4–30), while it was 8 mm (range, 5–20) in men. The median inlet patch number was 1 in both sexes (range, 1–3 in women, 1–2 in men). Forceps biopsy was possible in 30 (56.6%) patients. We found no additional esophageal pathology in 45 (84.9%) patients, normal lower esophageal sphincter in 39 (73.5%), incompetent lower esophageal sphincter in 14 (26.4%), hiatal diaphragmatic hernia in 1 (1.8%), and endoscopic antral gastritis in 29 (55.7%) patients. Twelve (54.5%) of 22 endoscopic biopsies were positive for Helicobacter pylori. We detected esophageal inlet patch in the distal esophagus in 2 (3.7%) patients. Conclusion: Esophageal inlet patch was more common in women, unrelated to gastroesophageal reflux disease, and most patients were asymptomatic, with a median size of 8 mm (range, 4–30), with no gender difference. Moreover, inlet patch size was not associated with presence of symptoms. Evidence of malignancy in the biopsied inlet patches was not observed.
PENGEMBANGAN E-MODUL MODEL EKSPERIENTAL JELAJAH ALAM SEKITAR (EJAS) PADA MATERI PLANTAE
Authors: Basaroh Anisah Suroya , Al Muhdhar Mimien Henie Irawati , Prasetyo Triastono Imam , Sumberartha I Wayan , Mardiyanti Lely , Fanani Zainal
Published: August 2021

Abstrak. Penelitian pengembangan ini bertujuan untuk menguji kevalidan dan kepraktisan E-modul model Eksperiental Jelajah Alam Sekitar (EJAS) pada materi plantae. Produk yang dikembangkan menggunakan model pengembangan ADDIE. Model pembelajaran yang digunakan yaitu Model Eksperiental Jelajah Alam Sekitar (EJAS). Subjek penelitian adalah 30 siswa kelas X IPA B SMAN 01 Singosari. Hasil implementasi berupa data hasil validasi validator ahli dan data angket respon siswa sebagai pengguna E-modul. Hasil validasi e-modul oleh ahli media sebesar 99 persen, hasil validasi oleh ahli materi berupa hasil validasi komponen materi e-modul sebesar 100 persen. Hasil validasi oleh ahli perangkat pembelajaran dan praktisi lapangan berturut-turut menunjukkan persentase sebesar 98 persen dan 97 persen. Data kepraktisan setelah implementasi e-modul yakni sebesar 88 persen. Hasil analisis dari masing-masing uji menunjukkan bahwa produk pengembangan telah dinyatakan sangat valid dan sangat praktis. E-modul model Eksperiental Jelajah Alam Sekitar (EJAS) materi plantae yang dikembangkan telah memenuhi syarat kevalidan dan kepraktisan untuk digunakan dalam pembelajaran matei plantae.Abstract. The development research aims to test the validity and practicality of the E-module model of Experiential Exploration of Natural Exploration (EJAS) on plantae material. Products developed using the ADDIE development model. The learning model used is the Experimental Model of Natural Exploration (EJAS). The research subjects were 30 students of class X IPA B SMAN 01 Singosari. Implementation result showed from the validation results of expert validators and questionnaire data on student responses as E-module users. The results of the validation of e-module by media experts are 99 percent, the results of validation by material experts are in the form of validation results of the e-module material components by 100 percent. The results of the validation by instructional equipment experts and field practitioners showed a percentage of 98 percentand 97% percent, respectively. Practicality data after the implementation of e-module is 88 percent. The results of the analysis of each test indicate that the development product has been declared very valid and very practical. The E-module model of Experiential Exploration of Natural Exploration (EJAS) on plantae has met the validity and practicality requirements for use in learning plantae material.
ANALISIS SELF EFFICACY SEBAGAI DASAR PENGEMBANGAN SUMBER BELAJAR MANDIRI UNTUK PRAKTIKUM JARAK JAUH DI LPTK
Authors: Rizki Muhammad , Suryawati Evi , Zulfarina Zulfarina , Rahmi Fitri Olivia
Published: August 2021

Abstrak. Penelitian dilaksanakan dalam dua tahap 1) Analisis kebutuhan dengan melibatkan 159 orang mahasiswa yang melaksanakan praktikum biologi. 2) Merancang sumber belajar berupa Virtual Laboratorium pada topik kultur jaringan tumbuhan, dalam tahapan ini design virtual yang dilakukan masih dalam masa pengembangan. Data self efficacy dengan 5 indikator yang terdiri dari (keyakinan menyelesaikan tugas, motivasi diri, kerja keras, mengatasi hambatan, dan menyelesaikan tugas dalam perspektif luas atau sempit) dikumpulkan dengan menggunakan kuisioner. Rancangan story board virtual lab didesign menggunakan software photoshop. Hasil penelitian menunjukkan rata-rata skor self efficacy terkait keyakinan menyelesaikan tugas (80), memotivasi diri (87), kerja Keras (87), mengatasi hambatan (80) dan self efficacy dalam menyelesaikan tugas dalam perspektif luas atau sempit (73). Hasil ini menunjukkan perlu adanya upaya untuk peningkatan self efficacy dengan mengembangkan su mber belajar untuk pelaksanaan praktikum berbasis teknologi informasi, salah satunya pengembangan virtual laboratorium yang dapat memfasilitasi mahasiswa dalam menyelesaikan tugas secara mandiri.Abstract. The research was carried out in two stages: 1) Needs analysis involving 159 students who carried out biology practicum. 2) Designing learning resources in the form of Virtual Laboratories on the topic of plant tissue culture, at this stage the virtual design is still under development. Self-efficacy data with 5 indicators consisting of (belief in completing tasks, self-motivation, hard work, overcoming obstacles, and completing tasks in a broad or narrow perspective) were collected using a questionnaire. The virtual lab storyboard design is designed using Photoshop software. The results showed that the average self-efficacy scores related to belief in completing tasks (80), self-motivation (87), hard work (87), overcoming obstacles (80) and self-efficacy in completing tasks in a broad or narrow perspective (73). These results indicate the need for efforts to increase self-efficacy by developing learning resources for the implementation of information technology-based practicums, one of which is the development of virtual laboratories that can facilitate students in completing assignments independently.
MEDIA DOMINASI (DOMINO SISTEM KOORDINASI) UNTUK SISWA KELAS XI SMA/MA
Authors: Sodiq Muhammad Yusuf Fajar , Sholihah Mar'atus , Anggraini Dian Puspita
Published: August 2021

Abstrak. Penelitian ini bertujuan untuk mengembangkan media domino sebagai media pembelajaran Biologi pada materi sistem koordinasi untuk siswa kelas XI SMA/MA. Data penelitian berupa data kelayakan media yang diambil dari hasil validasi ahli media, materi, bahasa, respon guru dan respon siswa. Pengambilan data pada penelitian ini menggunakan instrumen berupa angket validasi ahli media, materi, bahasa, respon guru serta respon siswa. Analisis data dilakukan secara deskriptif. Hasil validasi menunjukkan penilaian ahli materi memperoleh persentase sebesar 75 persen dengan kriteria layak, ahli bahasa sebesar 82,2 persen dengan kriteria sangat layak, ahli media sebesar 78 persen dengan kriteria layak, respon guru biologi 76,4 persen dengan kriteria layak, dan respon siswa sebesar 83,5 persen dengan kriteria sangat layak. Hasil yang diperoleh menunjukkan bahwa media dominasi layak digunakan sebagai media pembelajaran biologi khususnya materi sistem koordinasi untuk kelas XI SMA/MA.Abstract.This study aims to develop domino media as a learning media for biology in the coordination system material for class XI SMA / MA students. The research data is in the form of media feasibility data taken from the validation results of media experts, material, language, teacher responses and student responses. Retrieval of data in this study using instruments in the form of validation questionnaires for media experts, materials, language, teacher responses and student responses. Data analysis was carried out descriptively. The validation results showed that the material expert's assessment obtained a percentage of 75 percent with proper criteria, 82.2 percent of language experts with very feasible criteria, 78 percent of media experts with proper criteria, 76.4 percent of biology teacher responses with proper criteria, and student responses amounted to 83.5 percent with very feasible criteria. The results obtained indicate that the media of dominance is suitable for use as a media for learning biology, especially the material for the coordination system for class XI SMA / MA.
Evaluation of S-100 immunostaining in the demonstration of nerve changes in tuberculoid and borderline tuberculoid leprosy - A descriptive, prospective and retrospective analytical study
Authors: Manjunath Sowmya S , Manjunath G V , Basavaraj Vijaya
Published: August 2021

S-100 immunohistochemical staining may detect nerve involvement in early stages of tuberculoid spectrum of leprosy. This study investigated the use of S-100 in early diagnosis of the tuberculoid and borderline tuberculoid leprosy and compared its sensitivity with hematoxylin and eosin (HE) stains in discerning the nerve involvement.

To study the different histopathological patterns of nerve involvement in tuberculoid and borderline tuberculoid leprosy on S-100 immunostaining and also to compare the sensitivity of HE stain with S-100 immunostain in discerning the nerve involvement in these cases.

This was a descriptive, prospective and retrospective analytical study, which included patients with tuberculoid spectrum of leprosy. Histopathological examination (HPE) and immunohistochemical (IHC) analysis were performed on all skin biopsies using HE stain and S-100 immunostain, respectively. Then the sensitivities of both the stains in discerning the nerve involvement were calculated and the data was analyzed using SPSS software version 22 by applying chi-square test.

The study included a total of 58 patients [tuberculoid (n=28), borderline tuberculoid (n=30)]. The mean age was 43 yrs. The most common clinical manifestation was hypopigmented patches (n=40, 70%) with loss of sensation (n=39, 68.3%). HPE revealed 36 cases with well-defined granulomas, 22 cases with ill-defined granulomas and 41 cases with nerve destruction. IHC analysis showed four different patterns of nerve damage (fragmented, n=32; infiltrated and fragmented, n=14; infiltrated, n=10; intact, infiltrated and fragmented; n=1). The sensitivity and positive predictive value (PPV) of HE staining in delineating the nerve involvement were 68.96% and 100%, respectively. Whereas, the sensitivity and PPV of S-100 IHC were 100% each.

Less number of cases.

Use of S-100 IHC along with HPE aids in early, accurate and confirmatory diagnosis.
Hydatid cyst of spleen: A rare presentation
Authors: Thapa Garima , Aruna  , Shah Bikram
Published: August 2021

: Hydatid cyst is a parasitic infestation caused by Echinococcus granulosus. The spleen being rarely involved by the parasite, commonly involved organs are liver followed by lungs. It constitutes only 4% of abdominal hydatid diseases. Its worldwide incidence is 0.5 to 4%. In this case report, we present a case of young boy with concomitant splenic and liver hydatid cysts.

A 8-year-old boy, resident of Chamba district was presented with abdominal pain, fever and left upper quadrant swelling. The swelling had started enlarging over past 4 months. After necessary investigations it was diagnosed as hydatid cyst of spleen concomitant with liver and was confirmed by histopathological examination of the cyst membrane. All routine investigations other than anemia of 9.4 mg/dl and raised Ecchinococcus IGG serum levels, all other tests were within normal range.

Splenic hydatid is a rare entity and among abdominal presentations of hydatid diseases its incidence is very low, being 4% only. Diagnosis can be made on CECT abdomen along with the Echinococcus IGG serum levels, cytology of aspirated cystic fluid and then can be confirmed on histopathological examination of the cyst membrane sent for the histopathological examination.

This case report emphasizes the need of considering hydatid cyst as a differential with uncommon presentation of the disease even in non- endemic area, as in this case patient presented with splenomegaly and abdominal pain.
Granular cell tumour of cecum mimicking a neuroendocrine tumor
Authors: Pol Jaydeep N , Kadkol Girish A , Phadke Madhura D , Magdum Swpana S
Published: August 2021

Granular cell tumor (GCT) is a benign soft tissue neoplasm generally believed to be of nerve sheath origin. It is most frequently seen in skin, subcutaneous tissue and oral cavity. GCTs are uncommon in gastrointestinal tract (GIT), in which the majority are located in the esophagus. In this article, we report a case of GCT involving cecum in a 22 years lady. She had a sessile polyp in the cecum which was thought to be NET. Typical histomorphology and expression of S-100 on immunohistochemistry confirmed the diagnosis.

We have reviewed, the GCTs of cecum reported previously with emphasis on the differential diagnosis. To best of our knowledge, this is only the 3 case of GCT of cecum reported in the Indian literature.

Colonic GCTs are extremely uncommon. This is just the third case of GCT of colon in Indian literature. GCTs pose a diagnostic challenge due to lack of symptoms or nonspecific symptoms. Awareness of this entity helps in preventing misdiagnosis as happened in this case and avoiding further unnecessary treatment.
Cutaneous Malakoplakia of perianal skin: Report of a rare lesion at an unusual site
Authors: Magdum Swapna Somnath , Phadke Madhura D , Pol Jaydeep N , Kadkol Girish A
Published: August 2021

Malakoplakia is a rare chronic granulomatous inflammatory condition, commonly presenting in immunocompromised patients. It most commonly occurs in urinary tract. The cutaneous form is less frequent. Here, we report a case of cutaneous malakoplakia involving perianal skin in an immunocompetent 61-year old female diagnosed on histopathology utilizing special stains. To the best of authors’ knowledge, this is the 8case report of cutaneaous malakoplakia of perianal skin in the English literature and 3in the Indian literature.
US-UK “special relationship” and current challenges
Authors: Prikhodko Oleg
Published: August 2021

The Anglo-American “special relationship” has characteristics that make it distinct from other alliances led by the United States. The article covers a set of issues ranging from the bilateral nuclear cooperation to a broad web of military links between the US and the UK. It examines the phenomenon of the “special relationship”, its substance and manifestations in security and defense domains, including recent developments. The victory of Joe Biden in the United States 2020 Presidential election, that reversed ‘America First’ policy of D. Trump, makes the future relationship between the United States and the United Kingdom much more predictable. However, the British departure from the European Union is a milestone event with explicit and implicit implications for the policies of the US and the UK. Although it is premature to predict a resulting outcome of Brexit for their relationship, the prevailing view of American and British analysts is that the UK could lose a substantial part of its value for the United States in European matters. Nevertheless, the cooperation between Washington and London in security and defense issues will be no less intense. Moreover, a concept of ‘global Britain’ that is central to Boris Johnson’s foreign and security policies may prove more helpful to the U.S. strategy, especially beyond Europe. At least, an Indo-Pacific commitment on the part of post-Brexit Britain is a striking feature that lies fully in line with the U.S. strategic interests in the region.
Cultural Diplomacy in Canadian Foreign Policy
Authors: Shchukina Tatiana
Published: August 2021

In furthering its foreign policy, Canada, as other countries, uses its reputation, advantage and assets to enhance its national interest, and to strengthen its state-to-state, regional and international relations. Comprising a range of instruments, a country's culture and arts stand out as having the unique potential to enrich its foreign policy. Culture and arts have long played a role in Canada's international relations. Government of Canada should develop and implement a comprehensive cultural diplomacy strategy that establish its objectives within the context of Canada's foreign policy, articulate roles and responsibilities, and identify the budgetary resources necessary for the strategy's realization.
Rusycystyka w Izraelu. Od kulturowej separacji do demarginalizacji kultury rosyjsko-żydowskiej
Authors: Lenart Agnieszka
Published: August 2021

Celem badań jest omówienie kondycji izraelskiej rusycystyki. W tekście wskazuje się uwarunkowania społeczno-polityczne, które wpłynęły na wzrost rangi języka rosyjskiego, omawia się dynamikę spadku jego atrakcyjności, a także perspektywy zainteresowania kulturą rosyjską w Izraelu. Autorka artykułu wymienia nazwiska izraelskich rusycystów i slawistów, omawia ich preferencje badawcze i osiągnięcia w zakresie światowych badań slawistycznych. Badania izraelskich rusycystów dotyczą przede wszystkim literatury pierwszej fali emigracji rosyjskiej. W ostatnim czasie coraz częściej podejmowane są prace nad literaturą rosyjską w kontekście żydowskim i izraelskim. Z przeprowadzonej analizy wynika, że rusycystyka w Izraelu najbardziej intensywnie rozwijała się w latach 90. W XXI wieku zainteresowanie rusycystyką w Izraelu spada ze względu na słabszą znajomość języka i kultury rosyjskiej wśród młodszego pokolenia repatriantów. Wpływ na ten stan rzeczy mają także tendencje światowe i procesy globalizacyjne.
«Вечный муж» и традиция мениппеи
Authors: Segal-Rudnik Nina
Published: August 2021

The article examines the motif structure of the main characters in Dostoevsky’s The Eternal Husband against the background of menippea and its various genres. The parodic transformations of the images and motifs of Dostoevsky's previous texts, especially the novel The Idiot, modify the traditional love triangle of the short story. The relationship between the protagonist and the antagonist reflects the ambivalence of the archetypal scheme “king vs jester” and the way it appears in Hugo’s romantic drama Le Roi s’amuse and Verdi’s opera Rigoletto. The plot of revenge and vindication of trampled dignity dates back to the genre of medieval mock mystery (R. Jakobson) and its narrative of the Easter resurrection, posing the problem of Christianity and its values in the Russian society of the time.
Konceptualizacja śmiechu w językowym obrazie świata Nadieżdy Teffi (na materiale prozy wspomnieniowej)
Authors: Ndiaye Iwona Anna
Published: August 2021

W centrum uwagi badawczej Autorki pozostaje koncept смех w rosyjskiej literaturze emigracyjnej. Celem artykułu jest analiza danego konceptu w prozie wspomnieniowej Nadieżdy Teffi, pisarki pierwszej fali emigracji rosyjskiej. Przedmiot niniejszej analizy stanowi leksyka wyekscerpowana z tomów Wspomnienia (1933) oraz Moja kronika (2015). Analiza została ukierunkowana na wyodrębnienie semantycznej struktury konceptu oraz sposobów jego lingwistycznego wyrażenia w tekście literackim.

W procesie analizy odwołaliśmy się do metodologii zaproponowanej przez Josifa Sternina, co pozwoliło wyróżnić w strukturze konceptów różnorodne jednostki mentalne autorskiego obrazu świata, werbalizowane w tekstach literackich (sensy i wyobrażenia obiektywne oraz indywidualno-autorskie).

Ponadto w badaniu wykorzystano metodę opisową oraz analizę funkcjonalno-stylistyczną.

Na podstawie przeprowadzonej analizy lingwistycznej możemy wnioskować, że koncept смех jest szeroko reprezentowany w prozie wspomnieniowej Teffi. Indywidualno-autorskie znaczenia reprezentujące peryferie analizowanego konceptu mają różną konotację. Uczucia i emocje wyrażane za pomocą śmiechu w świecie przedstawionym są zarówno pozytywne, negatywne, jak i neutralne. Częstotliwości użycia jednostek leksykalnych oraz różnorodność ich aktualizacji świadczą o tym, że koncept СМЕХ zajmuje ważne miejsce w językowym obrazie świata Teffi.
Исследования Pоссии/СССР и стран Восточной Европы после холодной войны: новое лицо дисциплины
Authors: Bolshakova Olga
Published: August 2021

The paper deals with the new developments in the field of Russian and East European studies (REES) after the end of the Cold war, with the focus on the U.S. and Great Britain. Along with organizational and structural changes in the field special attention is devoted to new subjects and trends in the study of the region, with Belarus as a case study. Research in this field began in the 90s and has been booming since the 2000s. Researchers are primarily interested in the history of the country, political science, anthropology, and literary studies. The formation of an international community of researchers allows us to conclude that previously “Western” discipline of REES is gaining a global character.
Сэр Бернард Пэрс и Школа славянских исследований в Лондоне
Authors: Nekrasov Andrei
Published: August 2021

This article covers the diverse activities of the renowned British historian Sir Bernard Pares on the development of Russian and Slavic studies in the first half of the 20th century. He was the author of several books and a fair number of articles on Russia, edited the journals The Russian Review and The Slavonic Review. Pares also founded the first School of Russian Studies at the University of Liverpool (1907) and served for twenty years as Director of the School of Slavonic and East European Studies at the University of London (1919-1939). Due to his interest in Russian politics, history and culture, frequent and lengthy visits to Russia from 1906 to 1919 and close friendship with many Russian liberals, his appointment as an official observer to the Russian army in 1915 and as a British representative to Kolchak’s army during the Civil War, Pares became one of the most authoritative British experts on Russia and rightfully assumed the position of Director of the School of Slavonic Studies. This article pays close attention to various financial and administrative problems that Pares had to cope with as the Director of the School. The author concludes that Bernard Pares’ role as a promoter of all things Russian, a translator of Russian poetry and prose, a researcher into Russian history and an organiser of Russian and Slavonic studies in Britain was indispensable.
The Role of Domenico De Vivo in Developing Russian and Italian Language Studies in the Second Half of 19th Century
Authors: Cifariello Alessandro
Published: August 2021

Very little is known about Domenico De Vivo (1839-1897). He was a disciple of the Italian linguist Giacomo Lignana and worked as a professor of Russian and English language at the Asiatic College in Naples from 1868 to 1870, and then as an Italian language lecturer at the universities of Dorpat and Odessa in the Russian Empire from 1879 until his death in 1897. De Vivo championed his ideas on language teaching and learning in his books Grammatica della lingua russa [Russian Grammar for Italians] (Dorpat, 1882) and Prakticheskoe rukovodstvo dlya izucheniya ital’yanskogo yazyka [A Practical Guide to Learning Italian] (Odessa, 1886; Odessa, 1890), and in his Dizionario Italiano-Russo. Slovar’ ital’yansko-russkiy [Italian-Russian Dictionary] (Odessa 1894). The purpose of this article is to examine De Vivo’s life and works, which represent the first recorded attempt – in De Vivo’s own words – “to promote Russian language learning in Italy and Italian language learning in Russia.”
Особенности восприятия цвета в подростковом и взрослом возрасте
Authors: Белашина Т.В. , Тормышова А.С.
Published: August 2021

Статья посвящена проблеме исследования особенностей цветового восприятия в подростковом и взрослом возрасте. Представлены результаты эмпирического исследования на выборке, которую составили 67 человек, дифференцированных на две эмпирические группы: ЭГ-1 (подростки) и ЭГ-2 (взрослые). Показано, что для подросткового возраста более характерно затруднение в прохождении теста на световосприятие, т.е. проявление признаков недостаточно сформированного цветоощущения.
Психологическая работа с психоэмоциональным состоянием сотрудников ОВД, заступающих на службу с применением огнестрельного оружия
Authors: Коноплева Е.А. , Гришина Л.В. , Патрушев А.В.
Published: August 2021

Статья посвящена описанию частной методики, направленной на работу с психоэмоциональным состоянием сотрудников, заступающих на службу с применением огнестрельного оружия для решения оперативных задач, с использованием мобильного центра психологической подготовки сотрудников полиции.
Использование онлайн-переводчиков как средство обучения иностранному языку: преимущества и недостатки
Authors: Вельдина Ю.В.
Published: August 2021

В статье рассматривается проблема целесообразности и эффективности использования онлайн-переводчиков при изучения иностранного языка. Актуальность выбранной темы обусловлена тем, что в настоящее время наблюдается растущая активность интереса к переводу иностранных текстов через онлайн-переводчики, так как они бесплатны, удобны и не требуют установки. В данной статье автором рассматриваются особенности перевода иностранных текстов при помощи онлайнпереводчиков, приводятся примеры наиболее часто используемых онлайнпереводчиков и выделяются их преимущества и недостатки.
«Воспитание» мышления – как условие формирования гармоничной личности
Authors: Ильина Ю.А.
Published: August 2021

В статье предлагается философское осмысление воспитательной деятельности применительно к реалиям современности. Особое внимание уделено анализу специфики диалогичности мышления как основополагающего компонента гносеологического аспекта феномена воспитания.
Объектная и социокультурная обусловленность научного познания и его динамики
Authors: Мироненко В.В. , Гулякин Д.В.
Published: August 2021

Рассмотрена социокультурная обусловленность научного познания, его динамика, основные свойства. Рассмотрен метод научного познания в плане детерминации, а также значимость научного познания.
Использование математических заданий творческого характера с целью развития вариативности мышления младших школьников
Authors: Смирнова С.И.
Published: August 2021

В статье рассматривается значимость формирования вариативности мышления младших школьников в контексте становления творческой деятельности. Приводятся требования к организации творческой деятельности, виды и примеры заданий творческого характера.
Psychological and pedagogical difficulties of parents raising children with disabilities in terms of inclusive practice
Authors: Chemerilova I.A.
Published: August 2021

The paper presents experimental survey of parents of children with disabilities. The aim of this study was to identify psychological and pedagogical difficulties of parents of children with disabilities in terms of inclusive practices. Implementation of research tasks was achieved on the basis of methods of psychological diagnostics. The study showed that parents raising children with disabilities face many psychological and pedagogical difficulties. These difficulties hinder the development of parental competencies that are necessary for full child’s involvement in an inclusive process.
Творчество Мустая Карима - достояние общечеловеческой культуры
Authors: Гареева Г.Н.
Published: August 2021

Славный сын башкирского народа Мустай Карим – Мустафа Сафич Каримов - великий гуманист, Народный поэт Республики Башкортостан, писатель, драматург, публицист, гражданин и воин-защитник Родины, выдающийся общественный деятель, человек большой души и доброго сердца - внес огромный вклад в сокровищницу мировой литературы, поднял на новый уровень традиции классической башкирской литературы, его творчество стало олицетворением Башкортостана. В данной статье ставится целью выявление многогранного таланта Мустая Карима как художника, ставшего целой эпохой башкирской, российской, мировой литературы, из-под пера которого вышли выдающиеся произведения.
Социолингвистический аспект изучения визуальных субтитров в корейских развлекательных телепрограммах
Authors: Потапова Д.Н.
Published: August 2021

Статья посвящена определению визуальных субтитров корейского телевидения как соответствующего объекта социолингвистического анализа. Рассматривается специфика использования визуальных субтитров в корейских развлекательных телепрограммах, которые сегодня являются одним из важнейших компонентов южнокорейского телевидения, расширив свою роль с течением времени и эволюции функций субтитрирования и изменения самих развлекательных программ. Таким образом, визуальные субтитры представляют собой пласт интересный для изучения с социолингвистической стороны, в которых определенно можно заметить влияние социальных факторов на систему языка, а также роли языка субтитров в функционировании и развитии общества, как и подобает социолингвистическому аспекту.
Американский и британский английский: сходства и различия
Authors: Ситникова О.А.
Published: August 2021

Будучи одним из самых популярных языков, английский имеет множество разновидностей. На английском говорят люди, населяющие США, Индию, Пакистан, Великобританию, Германию, Канаду, Австралию и Индию. Однако в первую очередь носители английского ассоциируются с Великобританией и Соединенными Штатами. Говоря о степени родства и различия между британским и американским английским, нельзя не вспомнить слова Джорджа Бернарда Шоу о том, что Соединѐнные Штаты и Великобритания — две страны, разделѐнные общим языком. Таким образом, наша статья посвящена разнице между британским и американским английским.
Способы перевода разговорной речи в переводе романа «Мальчики и мужчины» Тони Парсонса
Authors: Старостенко А.С. , Лущека А.Д. , Шургучинов Ц.С.
Published: August 2021

Разговорная лексика является неотъемлемой частью любого художественного произведения, так как позволяет передать характер и особенности персонажей, окружающую их среду, а также ввести читателя в культуру и внутренний мир произведения. Однако при переводе таких компонентов могут возникнуть трудности передачи разговорной единицы исходного языка на переводной, поскольку переводчику необходимо рассматривать элементы двух разных культур. В данной статье рассмотрены способы перевода разговорной речи на примере перевода романа «Мальчики и мужчины» Тони Парсонса.
Эффекты дезорганизации управления бизнесом
Authors: Несмеянова Е.И.
Published: August 2021

Важно понять природу проявления конфликта интересов/оппортунизма, фаворитизма/кронизма в условиях дезорганизации управления в бизнесе. На основе исследования сути возникающих явлений в основе конфликта интересов/оппортунизма, фаворитизма/кронизма, определить причину проявления негативных эффектов, возникающих во взаимодействии наѐмных директоров и персонала, возможность исключения влияния этих эффектов на интересы владельца бизнеса.
Исследование параметров процесса торможения пули, влияющих на качество проведения контрольного отстрела огнестрельного оружия
Authors: Алексенцева С.Е.
Published: August 2021

В статье изложены результаты исследования особенностей деформации пули в процессе торможения в рабочей тормозной среде при контрольном отстреле огнестрельного нарезного оружия, факторы обеспечения показателей качества.
Сущность социальных процессов
Authors: Петрова С.И.
Published: August 2021

Социальные процессы как специфические формы социальных преобразований, реализуются в зависимости от сопутствующих ему ситуаций, обусловленных как масштабом общественных изменений, так и тем, какой субъект является детерминантом социального процесса и конкретной социальной сферой, в которой он развивается. Показывается, что социальный процесс - это способ осуществления движения социального бытия из потенциального в реальное. Тот тип изменений, который заключается в преобразовании общественных форм характеризующихся определенной ступенью социального, экономического и культурного развития. Переход от одного порядка пространственно-временных отношений общества к другому, посредством структурирования нового социального бытия, опосредованного прошлой историей и опытом.
Опыт выращивания однолетних саженцев сосны крымской с применением рибава-экстра
Authors: Чукарина А.В.
Published: August 2021

Выращивание однолетних саженцев сосны крымской в условиях сухого бора с применением двукратной обработки регулятором роста рибав-экстра на перовом этапе испытаний показало незначительное влияние биохимического препарата на ростовую активность растений.