bluuebunny/crossref_metadata_2025 huggingface dataset:
An equation-of-state-meter for CBM using PointNet
Authors: Kuttan Manjunath Omana , Zhou Kai , Steinheimer Jan , Redelbach Andreas , Stoecker Horst
Published: October 2021

Abstract

A novel method for identifying the nature of QCD transitions in heavy-ion collision experiments is introduced. PointNet based Deep Learning (DL) models are developed to classify the equation of state (EoS) that drives the hydrodynamic evolution of the system created in Au-Au collisions at 10 AGeV. The DL models were trained and evaluated in different hypothetical experimental situations. A decreased performance is observed when more realistic experimental effects (acceptance cuts and decreased resolutions) are taken into account. It is shown that the performance can be improved by combining multiple events to make predictions. The PointNet based models trained on the reconstructed tracks of charged particles from the CBM detector simulation discriminate a crossover transition from a first order phase transition with an accuracy of up to 99.8%. The models were subjected to several tests to evaluate the dependence of its performance on the centrality of the collisions and physical parameters of fluid dynamic simulations. The models are shown to work in a broad range of centralities (b=0–7 fm). However, the performance is found to improve for central collisions (b=0–3 fm). There is a drop in the performance when the model parameters lead to reduced duration of the fluid dynamic evolution or when less fraction of the medium undergoes the transition. These effects are due to the limitations of the underlying physics and the DL models are shown to be superior in its discrimination performance in comparison to conventional mean observables.
Exponential BPS Graphs and D Brane Counting on Toric Calabi-Yau Threefolds: Part I
Authors: Banerjee Sibasish , Longhi Pietro , Romo Mauricio
Published: October 2021

We study BPS spectra of D-branes on local Calabi-Yau threefolds $$\mathcal {O}(-p)\oplus \mathcal {O}(p-2)\rightarrow \mathbb {P}^1$$

O

(
-
p
)

⊕
O

(
p
-
2
)

→

P

1

with $$p=0,1$$

p
=
0
,
1

, corresponding to $$\mathbb {C}^3/\mathbb {Z}_{2}$$

C

3

/

Z
2

and the resolved conifold. Nonabelianization for exponential networks is applied to compute directly unframed BPS indices counting states with D2 and D0 brane charges. Known results on these BPS spectra are correctly reproduced by computing new types of BPS invariants of 3d-5d BPS states, encoded by nonabelianization, through their wall-crossing. We also develop the notion of exponential BPS graphs for the simplest toric examples, and show that they encode both the quiver and the potential associated to the Calabi-Yau via geometric engineering.
Bleeding pattern after medical management of early pregnancy loss with mifepristone–misoprostol and its prognostic value: a prospective observational cohort study
Authors: Enzelsberger Simon-Hermann , Wetzlmair Daniela , Hermann Philipp , Wagner Helga , Shebl Omar , Oppelt Peter , Trautner Philip Sebastian
Published: October 2021

Purpose

To improve counseling of women by reporting bleeding characteristics at home after medical management of an early pregnancy loss (EPL) with mifepristone and misoprostol, and to evaluate occurring bleeding patterns as a prognostic tool.

Methods

This prospective two-center observational cohort study enrolled 197 women who presented with an EPL (embryonic or anembryonic miscarriage) from December 2017 to April 2019 and chose a home-based medical management with 200 mg mifepristone and 800 mcg misoprostol. From the day of mifepristone intake, the strength of vaginal bleeding was recorded daily for 2 weeks by the patient herself using a diary sheet. Treatment success was defined as no histologically confirmed retained products of conception (RPOC) within 3 months. After considering all drop-out criteria, 154 women were included in the analysis.

Results

40.0% of patients (95% CI 30.4–49.6) already reported bleeding onset in the time period between the intake of mifepristone and misoprostol. The median duration of vaginal bleeding including spotting was 13 days. The chance of RPOC was about sixfold (OR 6.06, 95% CI 2.15–17.10) in the group of persistent bleeding after 2 weeks compared to the group with a terminated bleeding at that time. Exploratory regression analysis indicated association of higher serum levels of leukocytes at treatment start with RPOC (p = 0.013).

Conclusions

Terminated bleeding after 2 weeks is a useful indicator for successful medical induction of EPL. Women undergoing medical treatment with mifepristone must be informed about the high frequency of bleeding onset before misoprostol intake.

Clinical trial registration

DRKS—German Clinical Trials Register, ID: DRKS00013515, registration date 05.12.2017. http://www.drks.de/DRKS00013515.
Outcomes of a combination of augmented MicroPulse and limited Continuous Wave Cyclophotocoagulation in patients with refractory glaucoma
Authors: Gupta Sanchay , Chang Enchi Kristina , Chachanidze Marika , Hall Nathan , Neeson Cameron , Klug Emma , Chang Ta Chen , Solá-Del Valle David A.
Published: October 2021

Purpose

To assess the safety and effectiveness of augmented MicroPulse (MP-TSCPC) with limited Continuous Wave Transscleral Cyclophotocoagulation (CW-TSCPC) in patients with refractory glaucoma.

Methods

Thirty-eight eyes of 38 patients underwent combined MP-TSCPC and CW-TSCPC at Massachusetts Eye and Ear. Kaplan–Meier survival curves and Wilcoxon paired sign rank tests were performed to evaluate intraocular pressure (IOP), glaucoma medication burden, best corrected visual acuity (BCVA), and adverse events.

Results

With success defined as IOP reduction ≥ 30% and IOP between 5 and 18 mmHg, the cumulative probability of success at 1 year and 1.5 years were 0.81 (95% confidence interval (CI), 0.68–0.96) and 0.65 (95% CI, 0.50–0.86), respectively. With success defined as IOP reduction ≥ 50% and IOP between 5 and 18 mmHg, the success probability at 1 year and 1.5 years were 0.72 (95% CI, 0.57–0.89) and 0.56 (95% CI, 0.40–0.78), respectively. IOP and medication burden reductions were significant at all follow-up visits compared to baseline. Average IOP decreased from 27.9 mmHg at baseline to 11.4 mmHg at 1 year (p < 0.001) and 10.0 mmHg at 1.5 years (p < 0.001). Average medication burden decreased from 3.8 to 1.7 at 1.5 years (p = 0.001). No significant differences in visual acuity were observed at any time point. No long-term sight-threatening complications due to the combined procedure were observed, and most of the complications observed were mild and transient.

Conclusion

In patients with refractory glaucoma, the combination of augmented MP-TSCPC with limited CW-TSCPC provides a significant IOP-lowering effect and decrease in medication burden without increased risk of postoperative complications.
Laparoscopic iliopubic tract repair to treat recurrent pediatric inguinal hernia
Authors: Lee Sung Ryul
Published: October 2021

Background

Congenital defects, such as open processus vaginalis and the canal of Nuck, are common causes of primary pediatric inguinal hernia (PIH). However, in some patients, PIH occurs via acquired defects rather than congenital defects. The most representative cause of PIH is recurrent hernia. Recurrent PIH is treated with high ligation (HL), which is the same method that is used to treat primary PIH. However, the re-recurrence rate of recurrent PIH is high. This study aimed to compare laparoscopic iliopubic tract repair (IPTR) with laparoscopic HL for the treatment of recurrent PIH after primary PIH repair.

Methods

From June 2013 to March 2019, 126 patients (< 10 years old) with recurrent PIH were retrospectively enrolled. Patients were divided into two groups according to the operative technique: laparoscopic HL (58 patients) and laparoscopic IPTR (68 patients). With HL, the hernial sac was removed and the peritoneum closed. With IPTR, iliopubic tract and transversalis fascia sutures were applied.

Results

There were no cases of conversion to open surgery. Re-recurrence only occurred in the HL group; no patients in the IPTR group developed re-recurrence (8.6% [5/58] vs. 0.0% [0/68], respectively; p = 0.044). The mean duration from re-operation to re-recurrence in these five patients was 10.6 months. Other surgical outcomes and complications did not differ between the two groups.

Conclusions

Laparoscopic IPTR is an effective surgical treatment for reducing re-recurrence of recurrent PIH.
Lower help-seeking intentions mediate subsequent depressive symptoms among adolescents with high autistic traits: a population-based cohort study
Authors: Hosozawa Mariko , Yamasaki Syudo , Ando Shuntaro , Endo Kaori , Morimoto Yuko , Kanata Sho , Fujikawa Shinya , Cable Noriko , Iso Hiroyasu , Hiraiwa-Hasegawa Mariko , Kasai Kiyoto , Nishida Atsushi
Published: October 2021

Adolescents with high autistic traits are at increased risk of depression. Despite the importance of seeking help for early intervention, evidence on help-seeking intentions amongst this population is scarce. Using a population-based cohort in Japan, we examined adolescents’ help-seeking intentions and preferences by the level of autistic traits and tested its mediating role on the association between high autistic traits and depressive symptoms. At age 12, we measured parent-rated autistic traits using the short version of the Autism Spectrum Quotient and classified the adolescents into two groups (≥ 6 as AQhigh, < 6 as AQlow); help-seeking intentions and preferences were assessed through a depression vignette. At age 14, depressive symptoms were self-rated using the Short Mood and Feelings Questionnaire. Hypothesised associations between autistic traits and help-seeking intentions or depressive symptoms were tested applying multivariable regression modelling, while mediation was tested with structural equation modelling. Of the 2505 adolescent participants, 200 (8%) were classified as AQhigh. In both groups, the main source of help-seeking was their family; however, 40% of the AQhigh group reported having no help-seeking intentions compared to 27% in the AQlow. The AQhigh group was at increased risk of not having help-seeking intentions (OR 1.84, 95% CI 1.35–2.50) and higher depressive symptoms (b coefficient 1.06, 0.33–1.79). Help-seeking intentions mediated 18% of the association mentioned above. Interventions to promote help-seeking intentions among adolescents with high autistic traits could reduce their subsequent depressive symptoms. Ideally, such interventions should be provided prior to adolescence and with the involvement of their parents.
MechaTag: A Mechanical Fiducial Marker and the Detection Algorithm
Authors: Digiacomo Francesca , Bologna Francesco , Inglese Francesco , Stefanini Cesare , Milazzo Mario
Published: October 2021

Fiducial markers are fundamental components of many computer vision systems that help, through their unique features (e.g., shape, color), a fast localization of spatial objects in unstructured scenarios. They find applications in many scientific and industrial fields, such as augmented reality, human-robot interaction, and robot navigation. In order to overcome the limitations of traditional paper-printed fiducial markers (i.e. deformability of the paper surface, incompatibility with industrial and harsh environments, complexity of the shape to reproduce directly on the piece), we aim at exploiting existing, or additionally fabricated, structural features on rigid bodies (e.g., holes), developing a fiducial mechanical marker system called MechaTag. Our system, endowed with a dedicated algorithm, is able to minimize recognition errors and to improve repeatability also in case of ill boundary conditions (e.g., partial illumination). We assess MechaTag in a pilot study, achieving a robustness of fiducial marker recognition above 95% in different environment conditions and position configurations. The pilot study was conducted by guiding a robotic platform in different poses in order to experiment with a wide range of working conditions. Our results make MechaTag a reliable fiducial marker system for a wide range of robotic applications in harsh industrial environments without losing accuracy of recognition due to the shape and material.
A una flor nacida en una calavera: En torno al concepto de propagación contextual
Authors: Mañero Lozano David
Published: October 2021

This study deals with the way in which the literary motif of the flower born in a skull was transmitted. In particular, it is analyzed the textual formulation that emerged in baroque poetry and how it was projected later in several cultural contexts. In addition, this analysis tries to illustrate the concept of contextual propagation, which refers to a process of literary transmission that explains the survival and evolution of certain texts through new channels of expression involving a change in literary genre and even expressive medium.
Follow-up Psychiatric Care and Risk of Readmission in Patients with Serious Mental Illness in State Funded or Operated Facilities
Authors: Hermer Linda , Nephew Thomas , Southwell Kenona
Published: October 2021

Receipt of outpatient treatment within 30 days of discharge from psychiatric hospitalization is an established quality indicator; however, there is scant, mixed evidence as to whether it reduces the risk of readmission. We evaluated this question in patients hospitalized for schizophrenic, bipolar or depressive disorders using the Mental Health Treatment Episode Data Set (MH-TEDS), comprising patients in state-funded or -operated facilities and programs. We performed a 6-month, retrospective longitudinal cohort study including 44,761 patients with schizophrenic disorders, 45,413 patients with bipolar disorders, and 74,995 patients with depressive disorders with an index hospitalization between 2014 and 2018, stratified by whether they had at least one outpatient treatment admission in the first 30 days post-discharge. We used multivariable logistic regression to assess risk of readmission during days 31–180. We found that less than 10 percent of patients in the three cohorts received the recommended follow-up outpatient care. Furthermore, we found that schizophrenic and bipolar patients who did receive such care were no less likely to be readmitted than those not receiving such care (AOR = 0.96, 95% CI 0.87–1.06; AOR 1.06, 955 CI 0.98–1.14), and patients with depressive disorders receiving such care were more likely to be readmitted (AOR = 1.14, 95% CI 1.07–1.22). Thus, few patients received follow-up outpatient care within 30 days of discharge. When it occurred, such outpatient care was either not linked to reduced readmissions or was associated with increased readmissions. These findings suggest the need for more effective care processes in state-funded or -operated facilities.
The Influence of Covid-19 on Perceived Health Effects of Wetland Parks in China
Authors: Zhai Xuezhu , Lange Eckart
Published: October 2021

Wetland parks are designed to support urban ecological protection, flood control and human well-being. Existing research mainly focuses on their influence on ecology and economy. However, their influence on human well-being and health is rarely studied. In China, during the peak of the COVID-19 pandemic (Peak), people were very concerned about health, while at the same time wetland parks which are generally considered beneficial to health were closed. Thus, this study explores the public’s perception of the health effects of visiting wetland parks and the impact of the pandemic on the perception. From March 5th to 8th, 2020, before the Peak in China was over, 1,400 respondents participated in a nationwide online survey. It was found that the perceived benefits from visiting wetland parks were higher in terms of mental health than in physical health. Also, the perceived health benefits of wetland parks after the Peak were slightly higher than before the pandemic. The results highlight that wildlife habitat services were considered to be the most important ecosystem services that promote the perceived health benefits. Interestingly, the perceived health benefits of wetland parks by health experts appear to be lower than in other groups, indicating that the health benefits of visiting wetland parks may be overestimated by lay-people or underestimated by health experts. The results provide empirical evidence for managing ecosystem services as delivered by these urban wetlands, in the context of COVID-19 or potential future pandemics, for promoting public health.
Ethical reflections on the COVID-19 pandemic in the global seafood industry: navigating diverse scales and contexts of marine values and identities
Authors: Lam Mimi E.
Published: October 2021

The global crisis instantiated by the COVID-19 pandemic opens a unique governance window to transform the sustainability, resilience, and ethics of the global seafood industry. Simultaneously crippling public health, civil liberties, and national economies, the global pandemic has exposed the diverse values and identities of actors upon which global food systems pivot, as well as their interconnectivity with other economic sectors and spheres of human activity. In the wake of COVID-19, ethics offers a timely conceptual reframing and methodological approach to navigate these diverse values and identities and to reconcile their ensuing policy trade-offs and conflicts. Values and identities denote complex concepts and realities, characterized by plurality, fluidity and dynamics, ambiguity, and implicitness, which often hamper responsive policy-setting and effective governance. Rather than adopt a static characterization of specific value or identity types, I introduce a novel hierarchical conceptualization of values and identities made salient by scale and context. I illustrate how salient values and identities emerge at multiple scales through three seafood COVID-19 contextual examples in India, Canada, and New Zealand, where diverse seafood actors interact within local, domestic (regional/national), and global seafood value chains, respectively. These examples highlight the differential values and identities, and hence differential vulnerabilities, resilience, and impacts on seafood actors with the COVID-19 pandemic, which necessitate differentiated policy interventions if they are to be responsive to those affected. An ethical governance framework that integrates diverse marine values and identities, buttressed by concrete deliberation and decision-support protocols and tools, can transform the modus operandi of global seafood systems toward both sustainable and ethical development.
A Nonlinear Formulation of Radiation Stress and Applications to Cnoidal Shoaling
Authors: Paulsen Martin O. , Kalisch Henrik
Published: October 2021

In this article, we provide formulations of energy flux and radiation stress consistent with the scaling regime of the Korteweg–de Vries (KdV) equation. These quantities can be used to describe the shoaling of cnoidal waves approaching a gently sloping beach. The transformation of these waves along the slope can be described using the shoaling equations, a set of three nonlinear equations in three unknowns: the wave heightH, the set-down$${\bar{\eta }}$$η¯and the elliptic parameterm. We define a numerical algorithm for the efficient solution of the shoaling equations, and we verify our shoaling formulation by comparing with experimental data from two sets of experiments as well as shoaling curves obtained in previous works.
Spatiotemporal dynamics of glacial lakes (1990–2018) in the Kashmir Himalayas, India using Remote Sensing and GIS
Authors: Ahmed Rayees , Wani Gowhar Farooq , Ahmad Syed Towseef , Mir Riyaz Ahmad , Almazroui Mansour , Jain Sanjay K. , Ahmed Pervez
Published: October 2021

This study is perhaps the first attempt to use satellite data (1990–2018) to analyze spatiotemporal changes in glacial lakes over the Kashmir Himalayas supplemented by field studies. Landsat images were used to delineate the spatial extent of glacial lakes at four-time points, i.e., 1990, 2000, 2010 and 2018. The total count of lakes as well as their spatial extent showed a discernible increase. The number increased from 253 in 1990 to 324 in 2018, with a growth rate of 21.4%. The area has increased from 18.84 ± 0.1 km2 in 1990 to 22.13 ± 0.12 km2 in 2018 with a growth rate of 14.7%. The newly formed glacial lakes, including supraglacial lakes, were greater in number than the lakes that disappeared over the study period. All glacial lakes are situated at elevations of 2700 m asl and 4500 m asl. More than 78% of lake expansion in the study region is largely due to the growth of existing glacial lakes. Through area change analysis, our findings reveal that certain lakes show rapid expansion needing immediate monitoring and observation. The analysis of the meteorological variables reveals that minimum and maximum temperatures in the Jhelum basin have shown an increasing trend. Tmax showed an increase of 1.25 °C, whereas Tmin increased to 0.7 °C from 1980 to 2020. On the other hand, precipitation has shown a decreasing trend, which can be attributed to one of the major causes of glacier recession and the expansion of glacial lakes in the Upper Jhelum basin. Consequently, this study could play a significant role in devising a comprehensive risk assessment plan for potential Glacial Lake Outburst Floods (GLOFs) and developing a mechanism for continuous monitoring and management of lakes in the study region.
Effective equidistribution for generalized higher-step nilflows
Authors: KIM MINSUNG
Published: October 2021

In this paper we prove bounds for ergodic averages for nilflows on general higher-step nilmanifolds. Under Diophantine condition on the frequency of a toral projection of the flow, we prove that almost all orbits become equidistributed at polynomial speed. We analyze the rate of decay which is determined by the number of steps and structure of general nilpotent Lie algebras. Our main result follows from the technique of controlling scaling operators in irreducible representations and measure estimation on close return orbits on general nilmanifolds.
Effect of a parent agreement on return rates of Vanderbilt assessments and treatment adherence in pediatric attention-deficit/hyperactivity disorder patients
Authors: Torres Matthew , Miller Leslie , Payment Elizabeth , Patel Khushbu , Pawlowski Callie , Cortright Lindsay , Moore Jennifer , Tumin Dmitry , Higginson Amanda
Published: October 2021

Objective

We implemented a parent–teacher Vanderbilt agreement program to increase return rates of Vanderbilt assessment scales for children in our primary care practice, and compared the assessment return rate before and after agreement signature.

Methods

We retrospectively reviewed children diagnosed with attention-deficit/hyperactivity disorder (ADHD) who had a signed Vanderbilt agreement and were under continuous care at our clinic. Return rates were compared 1 year before and 1 year after the agreement date.

Results

Among 195 children, prior to the agreement, 71% returned teacher assessments, and 59% returned parent forms; after the intervention, assessment rates were not significantly different (76%,p = .255; and 65%,p = .185, respectively). The median number of returned assessments increased after the agreement.

Conclusions

Lack of documented parent and teacher Vanderbilt assessments remain a barrier to appropriate management of ADHD. Improving the rate of assessments returned is an important outcome for treating ADHD in the primary care setting.
Statistics of local Reynolds number in box turbulence: ratio of inertial to viscous forces
Authors: Kaneda Yukio , Ishihara Takashi , Morishita Koji , Yokokawa Mitsuo , Uno Atsuya
Published: October 2021

In high-Reynolds-number turbulence the spatial distribution of velocity fluctuation at small scales is strongly non-uniform. In accordance with the non-uniformity, the distributions of the inertial and viscous forces are also non-uniform. According to direct numerical simulation (DNS) of forced turbulence of an incompressible fluid obeying the Navier–Stokes equation in a periodic box at the Taylor microscale Reynolds number

$R_\lambda \approx 1100$

, the average

$\langle R_{loc}\rangle$

over the space of the ‘local Reynolds number’

$R_ {loc}$

, which is defined as the ratio of inertial to viscous forces at each point in the flow, is much smaller than the conventional ‘Reynolds number’ given by

$Re \equiv UL/\nu$

, where

$U$

and

$L$

are the characteristic velocity and length of the energy-containing eddies, and

$\nu$

is the kinematic viscosity. While both conditional averages of the inertial and viscous forces for a given squared vorticity

$\omega ^{2}$

increase with

$\omega ^{2}$

at large

$\omega ^{2}$

, the conditional average of

$R_ {loc}$

is almost independent of

$\omega ^{2}$

. A comparison of the DNS field with a random structureless velocity field suggests that the increase in the conditional average of

$R_ {loc}$

with

$\omega ^{2}$

at large

$\omega ^{2}$

is suppressed by the Navier–Stokes dynamics. Something similar is also true for the conditional averages for a given local energy dissipation rate per unit mass. Certain features of intermittency effects such as that on the

$Re$

dependence of

$\langle R_{loc}\rangle$

are explained by a multi-fractal model by Dubrulle (J. Fluid Mech., vol. 867, 2019, P1).
Presence of Parasite Remains in Historical Contexts in the City of Córdoba, Argentina, in the Nineteenth Century
Authors: Ramirez Darío Alejandro , Lindskoug Henrik Bernhard , Nores Rodrigo
Published: October 2021

We conducted a paleoparasitological study on sediment samples from two trash pits and a cesspool, collected during an archaeological assessment of a building located in the historic downtown of the city of Córdoba, Argentina. People have used these premises for residential and commercial purposes since the beginning of the seventeenth century, although the samples analyzed correspond to nineteenth-century contexts. Light microscopy examination revealed the presence of parasite eggs of whipworm (Trichuris sp.), possibly roundworm (Ascaris lumbricoides), and tapeworm (taeniid). The presence of these fecal-oral and food-borne transmitted helminths supports other lines of evidence that indicate poor sanitation and hygiene habits and inadequate food processing, which may have contributed to the high incidence and mortality of gastrointestinal diseases recorded at that time. The paleoparasitological data agree with the historical information on the health status of the populations that inhabited the city of Córdoba in the past, especially in relation to their habits and diet.
Political shocks and asset prices
Authors: Carnahan Daniel , Saiegh Sebastian
Published: October 2021

We estimate how asset prices respond to a range of political shocks, including changes in a country's economic stewardship, national elections, coup d'états, wars, and terrorist attacks. Using an event study approach and daily prices from the Buenos Aires exchange (Argentina) between 1967 and 2020, we find that stock-market volatility increases in the days immediately following major policy-shifting events. These results hold irrespective of whether returns are measured in nominal terms, in local consumption units, or in US dollars. The most significant increase in post-event risk is associated with irregular government turnovers. Volatility also increases in the days immediately following a defeat in an international war, national elections, and changes in the country's economic stewardship. No changes in stock-market volatility occur, however, after terrorist attacks or when the date of a new administration's inauguration is publicly known and determined sufficiently far in advance.
Street Dance Activism Global Dance Meditation for Black Liberation Radical Embodied Dialogue August 19, 2020 Recorded over Zoom
Authors: McIntyre Dianne , Yearby Marlies , jun grace shinhae , Bell Shamell , Park MiRi
Published: October 2021

Global Dance Meditation for Black Liberation began with Dr. Shamell Bell's dream, a clear vision of people around the world heeding a call, at the same time, to the same rhythm, in a collective resonance. It has grown into a conversation, a community, a journey, and a call to action. This Radical Embodied Dialogue was created to honor Black dance artists and their legacies. As part of the Street Dance Activism Global Dance Meditation for Black Liberation twenty-eight-day collective healing project, we invited Marlies Yearby and Dianne McIntyre to share their stories and their shared histories. The pandemic, coupled with use of technology, opened up and provided alternative methods to host a gathering and listen to their experiences that have too often been excluded from dance history texts. This resulting documentation of some of the work of these artists restores the significance of their work to American dance history.
Social Determinants and Health Behaviours among Older Adults Experiencing Multimorbidity Using the Canadian Longitudinal Study on Aging
Authors: Wister Andrew
Published: October 2021

This study examines associations between lifestyle behavioural factors and appraisals of “healthy aging” among older adults experiencing multimorbidity. A Social Determinants and Health Behaviour Model (SDHBM) is used to frame the analyses. Using baseline data from the Canadian Longitudinal Study on Aging (CLSA), we studied 12,272 Canadians 65 years of age or older who reported 2 or more of 27 chronic conditions. Additional analyses were conducted using three multimorbidity clusters: cardiovascular/metabolic, musculoskeletal, and mental health. Using hierarchical logistic regression, it was found that, for multmorbidity and the three illness clusters, healthy aging is consistently associated with not smoking (except for the mental health cluster), an absence of obesity (except for the cardiovascular and metabolic cluster), better sleep, and a better appetite. It is not associated with inactivity. Several socio-demographic, environmental, and illness covariates were also supported. The findings are examined using the SDHBM coupled with a resilience lens in order to elucidate how modifiable health behaviours can act as resources to mitigate multimorbidity adversities. This has implications for healthy aging for persons with multimorbidity, especially during the COVID-19 pandemic.
Extending the Tutte and Bollobás–Riordan polynomials to rank 3 weakly coloured stranded graphs
Authors: Avohou Remi C. , Ben Geloun Joseph , Hounkonnou Mahouton N.
Published: October 2021

The Bollobás–Riordan (BR) polynomial [(2002), Math. Ann.323 81] is a universal polynomial invariant for ribbon graphs. We find an extension of this polynomial for a particular family of combinatorial objects, called rank 3 weakly coloured stranded graphs. Stranded graphs arise in the study of tensor models for quantum gravity in physics, and generalize graphs and ribbon graphs. We present a seven-variable polynomial invariant of these graphs, which obeys a contraction/deletion recursion relation similar to that of the Tutte and BR polynamials. However, it is defined on a much broader class of objects, and furthermore captures properties that are not encoded by the Tutte or BR polynomials.
Revisiting the playground: Charles Wicksteed, play equipment and public spaces for children in early twentieth-century Britain
Authors: Winder Jon
Published: October 2021

This article offers the first detailed history of the children's playground in Britain in the early twentieth century. Despite being a common feature of towns and cities, the playground has rarely been examined by historians. In response, the article charts how changing conceptions of childhood, alternative visions of the city, technological innovation and shifting ideas about health and exercise shaped both the imagined function and material form of the playground ideal. Making visible the historical assumptions hidden in playground swings and slides helps to contextualize both existing scholarship on the mid-twentieth-century adventure playground and present-day efforts to create more equitable urban environments.
Visual stimulus features that elicit activity in object-vector cells
Authors: Andersson Sebastian O. , Moser Edvard I. , Moser May-Britt
Published: October 2021

Object-vector (OV) cells are cells in the medial entorhinal cortex (MEC) that track an animal’s distance and direction to objects in the environment. Their firing fields are defined by vectorial relationships to free-standing 3-dimensional (3D) objects of a variety of identities and shapes. However, the natural world contains a panorama of objects, ranging from discrete 3D items to flat two-dimensional (2D) surfaces, and it remains unclear what are the most fundamental features of objects that drive vectorial responses. Here we address this question by systematically changing features of experimental objects. Using an algorithm that robustly identifies OV firing fields, we show that the cells respond to a variety of 2D surfaces, with visual contrast as the most basic visual feature to elicit neural responses. The findings suggest that OV cells use plain visual features as vectorial anchoring points, allowing vector-guided navigation to proceed in environments with few free-standing landmarks.
Intravital imaging strategy FlyVAB reveals the dependence of Drosophila enteroblast differentiation on the local physiology
Authors: Tang Ruizhi , Qin Peizhong , Liu Xiqiu , Wu Song , Yao Ruining , Cai Guangjun , Gao Junjun , Wu You , Guo Zheng
Published: October 2021

Aging or injury inDrosophilaintestine promotes intestinal stem cell (ISC) proliferation and enteroblast (EB) differentiation. However, the manner the local physiology couples with dynamic EB differentiation assessed by traditional lineage tracing method is still vague. Therefore, we developed a 3D-printed platform “FlyVAB” for intravital imaging strategy that enables the visualization of theDrosophilaposterior midgut at a single cell level across the ventral abdomen cuticle. Using ISCs in young and healthy midgut and enteroendocrine cells in age-associated hyperplastic midgut as reference coordinates, we traced ISC-EB-enterocyte lineages with Notch signaling reporter for multiple days. Our results reveal a “differentiation-poised” EB status correlated with slow ISC divisions and a “differentiation-activated” EB status correlated with ISC hyperplasia and rapid EB to enterocyte differentiation. Our FlyVAB imaging strategy opens the door to long-time intravital imaging of intestinal epithelium.
An aluminum lining to the dark cloud of silver resistance: harnessing the power of potent antimicrobial activity of γ-alumina nanoparticles
Authors: Dassanayake Thiloka M. , Dassanayake Arosha C. , Abeydeera Nalin , Pant Bishnu D. , Jaroniec Mietek , Kim Min-Ho , Huang Songping D.
Published: October 2021

PEG-coated γ-Al2O3 NPs obtained by the top-down sonication technique exhibit potent antibacterial activity and can overcome Ag resistance in the AgNP-treated bacterial mutants.
Designing amphiphilic Janus nanoparticles with tunable lipid raft affinity via molecular dynamics simulation
Authors: Lin Xiaoqian , Lin Xubo
Published: October 2021

The raft affinity and membrane insertion depth of a Janus nanoparticle can be jointly modulated by the hydrophobicity and hydrophilicity of its surface ligands.
Biocompatible MOF-808 as an iodophor antimicrobial agent with controlled and sustained release of iodine
Authors: Nakhaei Mojdeh , Akhbari Kamran , Davoodi Alireza
Published: October 2021

I2@MOF-808 was prepared to investigate the amount of I2 adsorbed on MOF-808. By antibacterial tests, it was also confirmed that it could be considered as a biocide without the problem of microbial resistance and instability of iodine.
Creating supramolecular semiregular Archimedean tilings via gas-mediated deprotonation of a terminal alkyne derivative
Authors: Hu Wenqi , Zhang Hexu , Cheng Peng , Chen Lan , Chen Zhi , Klyatskaya Svetlana , Ruben Mario , Barth Johannes V. , Wu Kehui , Zhang Yi-Qi
Published: October 2021

Combining surface-confined reactions with supramolecular self-assembly allows the chemical transformation of simple molecular precursors into higher-level tectons to generate complex tessellations with unique structural and functional properties.
A red-light-chargeable near infrared MgGeO3:Mn2+,Yb3+ persistent phosphor for bioimaging and optical information storage applications
Authors: Wang Weili , Yan Shao , Liang Yanjie , Chen Dongxun , Wang Fang , Liu Jingwei , Zhang Yi , Sun Kangning , Tang Dongqi
Published: October 2021

An NIR-emitting MgGeO3:Mn2+,Yb3+ persistent phosphor chargeable with red light has been developed. The features of red-light charging and NIR persistent luminescence make this phosphor hold great potential for biomedical imaging and optical data storage.
NIR absorbing aromatic (antiaromatic) vinylogous carbasapphyrins (3.3.1.0.1) with built-in fused dipolar aromatic hydrocarbon: synthesis and characterization
Authors: Sahoo Sumit , Velmurugan Gunasekaran , Chakraborty Buddhadeb , Comba Peter , Rath Harapriya
Published: October 2021

Variants of vinylogous core modified carbasapphyrins with a built-in fused dipolar aromatic hydrocarbon moiety paving the way to a strong diatropicity/paratropicity with vis-NIR absorption.
High throughput screening of novel tribromide perovskite materials for high-photovoltage solar cells
Authors: Chen Shi , Zhang Lihua , Liu Yanliang , Zhang Zhuoqiong , Li Yang , Cai Weizheng , Lv Haiyan , Qin Yanchun , Liao Qianlong , Zhou Bin , Yan Ting , Ren Jie , Chen Shuming , Xiang Xiaodong , Dai Songyuan , So Shu Kong , Wang Xingzhu , Yang Shihe , Xu Baomin
Published: October 2021

A highly efficient composition screening protocol based on high throughput inkjet printing of perovskite films is developed to accelerate the discovery of novel tribromide perovskites for high-photovoltage solar cells.
Recent development in graphdiyne and its derivative materials for novel biomedical applications
Authors: Khan Karim , Tareen Ayesha Khan , Iqbal Muhammad , Mahmood Asif , Mahmood Nasir , Shi Zhe , Yin Jinde , Qing Duan , Ma Chunyang , Zhang Han
Published: October 2021

Graphdiyne (GDY), which possess sp- and sp2-hybridized carbon and Dirac cones, offers unique physical and chemical properties, including an adjustable intrinsic bandgap, excellent charge carrier transfer efficiency, and superior conductivity compared to other carbon allotropes.
Contributions of photochemistry to bio-based antibacterial polymer materials
Authors: Versace Davy-Louis , Breloy Louise , Palierse Estelle , Coradin Thibaud
Published: October 2021

Contribution of photochemistry for the synthesis of bio-based antibacterial polymer materials.
Synergetic enhancement of room-temperature phosphorescenceviawater molecules as a hydrogen bonding bridge
Authors: Gao Hao , Ding Bingbing , Wang Chao , Ma Xiang
Published: October 2021

To improve the water and oxygen resistance of room-temperature phosphorescence based on copolymerization strategy, a facile secondary processing strategy using water as the hydrogen bridge was proposed, which extended the lifetime and quantum yield.
Improving the device performance of organic solar cells with immiscible solid additives
Authors: Chen Shuaishuai , He Chengliang , Li Yaokai , Chen Tianyi , Xia Xinxin , Fu Weifei , Shi Minmin , Lu Xinhui , Zuo Lijian , Chen Hongzheng
Published: October 2021

We developed a solid additive (uv-9) showing immiscibility with active layers for morphology control, a PCE of 17.18% was achieved, which is much higher than those of devices without any additives. Moreover, the generality of uv-9 has been verified.
An ultrasensitive PVDF-based molecularly imprinted fluorescent test strip for the rapid and off-line detection of 4-NP with improved anti-coffee ring effect
Authors: Xu Yeqing , Huang Ting , Hu Bo , Meng Minjia , Yan Yongsheng
Published: October 2021

A PVDF-based test strip was prepared for offline visual detection of 4-NP. The test strip was optimized by paper materials and visual effects. F-PDA was used as a fluorescent functional monomer to improve the response time of test strip to 4-NP.
More Than Just a Weed: An Exploration of the Antimicrobial Activity of Rumex crispus using a Multivariate Data Analysis Approach
Authors: Pelzer Chantal V. , Houriet Joëlle , Crandall William J. , Todd Daniel A. , Cech Nadja B. , Jones Derick D.
Published: October 2021

Plants have a long history of use for their medicinal properties. The complexity of botanical extracts presents unique challenges and necessitates the application of innovative approaches to correctly identify and quantify bioactive compounds. For this study, we used untargeted metabolomics to explore the antimicrobial activity of Rumex crispus (yellow dock), a member of the Polygonaceae family used as an herbal remedy for bacterial infections. Ultra-performance liquid chromatography coupled with high resolution mass-spectrometry (UPLC-MS) was used to identify and quantify the known antimicrobial compound emodin. In addition, we used biochemometric approaches to integrate data measuring antimicrobial activity from R. crispus root starting material and fractions against methicillin-resistant Staphylococcus aureus (MRSA) with UPLC-MS data. Our results support the hypothesis that multiple constituents, including the anthraquinone emodin, contribute to
the antimicrobial activity of R. crispus against MRSA.
Site-Selective C(sp3)–H Functionalizations Mediated by Hydrogen Atom Transfer Reactions via α-Amino/α-Amido Radicals
Authors: Barham Joshua P. , Kaur Jaspreet
Published: October 2021

Amines and amides, as N-containing compounds, are ubiquitous in pharmaceutically-active scaffolds, natural products, agrochemicals, and peptides. Amides in nature bear a key responsibility for imparting three-dimensional structure, such as in proteins. Structural modifications to amines and amides, especially at their positions α to N, bring about profound changes in biological activity oftentimes leading to more desirable pharmacological profiles of small drug molecules. A number of recent developments in synthetic methodology for the functionalizations of amines and amides omit the need of their directing groups or pre-functionalizations, achieving direct activation of the otherwise relatively benign C(sp3)–H bonds α to N. Among these, hydrogen atom transfer (HAT) has proven a very powerful platform for the selective activation of amines and amides to their α-amino and α-amido radicals, which can then be employed to furnish C–C and C–X (X = heteroatom) bonds. The abilities to both form these radicals and control their reactivity in a site-selective manner is of utmost importance for such chemistries to witness applications in late-stage functionalization. Therefore, this review captures contemporary HAT strategies to realize chemo- and regioselective amine and amide α-C(sp3)–H functionalization, based on bond strengths, bond polarities, reversible HAT equilibria, traceless electrostatic-directing auxiliaries, and steric effects of in situ-generated HAT agents.

1 Introduction

2 Functionalizations of Amines

3 Functionalizations of Carbamates

4 Functionalizations of Amides

5 Conclusion
Existe alguma associação entre gravidade de degeneração discal e dor lombar?
Authors: Foizer Guilherme Augusto , Paiva Vagner Cleyton de , Nascimento Rodrigo Domingues do , Gorios Carlos , Cliquet Júnior Alberto , Miranda João Batista de
Published: October 2021

Objetivo Avaliar a possibilidade de maiores graus de degeneração discal levarem a maiores dor e disfunção.

Métodos Exames de imagem por ressonância magnética (IRM) de 85 pacientes com lombalgia idiopática por mais de 12 semanas foram avaliados, sendo quantificado o grau de degeneração discal de acordo com a escala de Pfirrmann. O grau de Pfirrmann em cada espaço discal de L1-L2 a L5-S1, o grau máximo de Pfirrmann (Pfirrmann-max) entre os discos lombares, e a soma dos graus de Pfirrmann (Pfirrmann-soma) foram correlacionados (por meio do teste de Spearman) com o Índice de Incapacidade de Oswestry (IIO) e a escala visual analógica (EVA) de dor.

Resultados No total, 87% dos pacientes tinha degeneração discal moderada ou acentuada medida pelo Pfirrmann-max, sendo L4-L5 e L5-S1 os discos mais degenerados. Houve uma correlação de fraca a moderada entre o Pfirrmann-max (r = 0,330; p = 0.002) e a Pfirrmann-soma (r = 0,266; p = 0,037) e o IIO, e entre o grau de Pfirrmann em L1-L2 e o IIO e a EVA.

Conclusão A degeneração discal lombar moderada ou acentuada é frequente em indivíduos com lombalgia crônica idiopática, e tem um impacto negativo na qualidade de vida dos pacientes. Pequenos graus de degeneração discal em L1-L2 podem determinar maior grau de dor e maior incapacidade funcional.
Fixador externo tipo delta no manejo pós-operatório de retalhos microcirúrgicos no membro inferior: Experiência de um hospital terciário
Authors: Vasconcelos Bruno Moraes , Matiotti Neto Mario , Rezende Luis Guilherme Rosifini Alves , Cagnolati Amanda Favaro , Irusta Alex Eduardo Calderón , Mazzer Nilton
Published: October 2021

Objetivo Avaliar o uso de fixadores externos, na configuração kickstand do tipo delta, como método adjuvante no período pós-operatório de pacientes submetidos a retalhos livres nos membros inferiores.

Métodos Ao todo, 17 fixadores externos do tipo delta foram utilizados em pacientes submetidos a retalhos livres nos membros inferiores. A técnica cirúrgica foi realizada de forma padronizada, com o pino distal localizado 6 cm proximal à anastomose, e o pino proximal, 6cm distal à tuberosidade anterior da tíbia.

Resultados A idade média da amostra foi de 34,76 anos (variação: 15 a 66 anos). Foram selecionados 11 homens e 6 mulheres. Utilizou-se a artéria tibial posterior em 14 casos, e a tibial anterior, em 3 casos. O tempo médio de uso dos fixadores externos foi de 3,88 semanas. A taxa de reoperação foi de 17,64%; a de perda do retalho foi de 11,76%; a de sucesso foi de 88,23%; e a taxa de infecção foi de 5,9%.

Conclusão O uso de fixadores do tipo delta como método adjuvante no pós-operatório é confiável; porém, mais estudos são necessários para avaliar seu verdadeiro papel no pós-operatório.
Aspirina versus rivaroxabana na prevenção do tromboembolismo venoso após artroplastia total do joelho: Um ensaio clínico randomizado, controlado e duplo-cego
Authors: Hongnaparak Theerawit , Janejaturanon Jiranuwat , Iamthanaporn Khanin , Tanutit Pramot , Yuenyongviwat Varah
Published: October 2021

Objetivo A aspirina (ácido acetilsalicílico, AAS) e a rivaroxabana são anticoagulantes que vêm ganhando popularidade devido à facilidade de uso na prevenção do tromboembolismo venoso (TEV) após artroplastia total do joelho (ATJ). Este estudo teve como objetivo avaliar a eficácia do AAS em comparação com a da rivaroxabana na profilaxia de TEV em pacientes submetidos a ATJ.

Método Quarenta pacientes com osteoartrite primária do joelho, que seriam submetidos a ATJ, foram randomizados em dois grupos. No total, 20 pacientes do grupo AAS usaram aspirina oral, na dose de 300 mg/dia, para a profilaxia do TEV após ATJ; e 20 pacientes do grupo rivaroxabana receberam uma dose oral de 10 mg/dia. No 4° e 14° dias do pós-operatório, trombose venosa profunda (TVP) dos membros inferiores no lado da cirurgia foi detectada por meio de ultrassonografia duplex. Foram registradas outras complicações durante catorze dias.

Resultados Não foram detectados achados positivos de TVP com a ultrassonografia duplex nos grupos de pacientes, e não se observou a ocorrência de embolia pulmonar. No total, 4 pacientes apresentaram equimose subcutânea no 4° dia do pós-operatório (2 pacientes no grupo AAS e 2 pacientes no grupo rivaroxabana; p = 1,0), e outros 4 pacientes, no 14° dia do pós-operatório (1 paciente no grupo AAS e 3 pacientes no grupo rivaroxabana; p = 0,292). Nenhum paciente da amostra apresentou hematoma da ferida cirúrgica, sangramento de órgão importante, infecção da ferida, ou necessidade de nova cirurgia.

Conclusão A aspirina e a rivaroxabana apresentaram eficácia comparável na prevenção do TEV, sem aumentar a incidência de complicações da ferida e sangramento após ATJ.