bluuebunny/crossref_metadata_2025 huggingface dataset:
Necrotizing pneumonia in pediatric intensive care unit
Authors: Benakanal Shreeshail V. , Manoj G. M. , Vikas K. G. , Manjula B.
Published: March 2023

Necrotizing pneumonia (NP) is a rare and severe complication of bacterial community-acquired pneumonia associated with high morbidity and mortality rate. We present a case series admitted in the pediatric intensive care unit (PICU) of our tertiary care hospital for 6 months. Five cases (positive blood culture) were selected based on the features of pneumonia with moderate-to-severe respiratory distress at admission. All cases are treated with antibiotics (piperacillin/tazobactam and vancomycin) as per blood culture and sensitivity results and oxygen therapy by high-flow nasal cannula/mechanical ventilation based on the decision of the treating physicians. Intercostal drainage tube was inserted for all empyema/pneumothorax cases. Decortication was done in two cases. Out of five cases, three cases were recovered after prolonged treatment in PICU and two cases succumbed to death in the 2nd week of hospitalization. Treatment of necrotizing pneumonia should be initiated early with broad-spectrum antibiotics along with staphylococcal cover till culture reports are awaited.
Assessment of Quality of Life in Vitiligo Patients in terms of Clinical Severity and Psychological Burden in a Tertiary Care Hospital
Authors: Sajan Cyril , Shah Priyanshi R. , Mahajan Rashmi , Chandrakar Vikas , Baxi Disha , Patel Hiral
Published: March 2023

Background:

Vitiligo is characterized depigmented macules and patches over the skin. It has a major impact on the quality of life (QoL) of patients, many of whom feel distressed and stigmatized by their condition.

Aim:

To assess QoL in vitiligo patients in terms of clinical severity and psychological burden.

Materials and Methods:

An observational study on 60 patients with age ≥16 years was conducted at an outpatient department of a tertiary care hospital. Data were collected in a predesigned pro forma. The QoL of patients and family members was assessed using Dermatology Life Quality Index (DLQI) and Family DLQI (FDLQI), respectively. The clinical severity was measured using Vitiligo Area Severity Index (VASI) and psychological burden by Vitiligo Impact Score-22 (VIS-22) questionnaire.

Results:

Sixty patients were included in the study. The mean age was 35.27 ± 2.24. Male-to-female ratio was 1.1:1. About 51.7% of patients were married. Majority of patients were students (30%). The time of presentation after disease onset was 5 years. About 20% of subjects had positive family history. The common sites were face (75%), lower limb (71.67%), and upper limb (60%), with leukotrichia in 11.7% of patients. The mean VASI score at baseline and at 1-month of follow-up after starting treatment was 4.11 ± 0.38 and 3.59 ± 0.58, respectively. The mean DLQI, FDLQI and VIS-22 score were 11.73 ± 0.80, 10.58 ± 0.71, and 37.32 ± 1.53, respectively. VIS-22 and VASI score correlated with changes in DLQI (P < 0.059).

Conclusion:

Vitiligo largely impairs the QoL of patients. The more the clinical severity (high VASI score), the higher the psychological burden, impairing QoL of patients, and family members.
Cerebellar Liponeurocytoma
Authors: Singh Kritika , Kolhe Ashvini , Goel Naina
Published: March 2023

Cerebellar liponeurocytoma is a rare clinicopathological entity, included in the 2000 World Health Organization (WHO) classification of tumors of the central nervous system in the category of glioneuronal tumors. These are WHO Grade II, slow-growing tumors in adults with known recurrences. To date, about 70 cases of liponeurocytomas have been reported. This tumor needs to be differentiated from oligodendroglioma as well as medulloblastoma which are more common and aggressive, requiring postoperative chemoradiation. A high index of suspicion is thus advocated for the diagnosis. We present one such case of this rare entity reported in our institute. A 42-year-old female presented with a 4-month history of headache, neck pain, reduced vision, and cerebellar signs. Imaging showed a midline lesion involving the cerebellar vermis and left lobe suggestive of anaplastic ependymoma/hemangioblastoma. The final diagnosis of cerebellar liponeurocytoma was rendered on routine histopathological examination supported by immunohistochemical analysis.
Attitude of Parents Toward Child's Dental Health during the COVID-19 Pandemic among the Population of Visnagar, Gujarat
Authors: Bafna Yash , Mehta Ruchir , Fernandes Shoba , Patel Dharati , Mistry Harsh , Shah Kavya
Published: March 2023

Aims:

This questionnaire-based survey was designed to assess the acquaintance, apprehension, and perceptions of parents toward the COVID-19 pandemic and toward seeking dental care for their children in Visnagar, Gujarat, India.

Settings and Design:

This was a questionnaire-based cross-sectional study.

Subjects and Methods:

The online Google survey form included 6 units with 27 close-ended questions in twin languages (regional and English). Inquiries covered demographics, changes in daily acts, dietary traditions, and preparedness to seek child oral care during November 2020 to January 2021.

Results:

Out of 400 parents, 172 responded to the electronic survey form. Over half of the guardians affirmed that alveolar treatment could fan out COVID-19. Around 90% resorted to medication (self-medication – 39%, home remedies – 32.6%, and teledentistry – 17.4%) to evade personal dental visits for their children.

Conclusions:

The awareness about COVID-19 and precautions was significantly high. Though parents were unaware about safeguards practiced by dentists during Covid19. Measures were taken to correct misconceptions among parents about safe dental procedures.
The Community of Men Who Have Sex with Men in Ratlam City, Madhya Pradesh
Authors: Sajan Cyril , Jacob Elizabeth
Published: March 2023

Background: Not long ago, the National AIDS Control Organization awakened the matter of men who have sex with men (MSM) and incorporated it as the most important group population. Targeted interventions (TI), as projected in the NACP-III, have made dauntless efforts to launch about, that this group demands an urgent and intensive attention, indicating a significant amount of departure from its previous polices. All above-mentioned reasons prompted us to undertake this study on evaluating the risk of MSM for sexually transmitted infections.

Methods:

A cross sectional descriptive study was conducted and all the acquired data were entered using epi info version 3.5 software and along with proper statistical procedures. Results: In the current study, 156 participants were involved, of which 90% of respondents were male and the remaining were transgender. Majority of the participants in the present study were involved in MSM activity with both regular and nonregular partners (RP)/casual partners. In the present study, 85.3% of the study participants were involved in MSM activity with a regular partner in the last 6 months, which is similar to nonregular partners reflecting high-risk activity.

Conclusion:

This study offers compelling evidence that MSM is more vulnerable to HIV due to a variety of variables. According to the current studies, about 37% of MSM were married. This brings up additional issues, such as the fact that women often contract HIV, because they are partners of men who are members of the population groups that are most at risk for HIV infection, such as MSM, rather than due to their own sexual behavior.
Medication Adherence and Adverse Drug Reactions of Isoniazid Preventive Therapy for Tuberculosis in People Living with HIV (PLHIV) in a Tertiary Care Teaching Hospital, Kakinada
Authors: Kruthika M. Mani , Devi Kandavalli Sri , Prasad K. V. Siva , Devi Pilla S. Surya Durga
Published: March 2023

Introduction:

Human immunodeficiency virus (HIV) and tuberculosis (TB) have a synergistic effect. Suppression of the immune system by HIV increases the risk for TB infection in people living with HIV (PLHIV). It is known for many years that isoniazid 300 mg for a period of 6 months is given for the prevention of TB.

Aim:

The present study is a prospective study to assess adverse drug reaction (ADR) and patient adherence to isoniazid in HIV patients on antiretroviral therapy (ART).

Subjects and Methods:

A prospective observational study was carried out for a period of 2 months, i.e., January 2021 and February 2021, in the department of ART at a tertiary care teaching hospital, Kakinada. This study was approved by the institutional ethics committee. The adherence to Isoniazid Preventive Therapy (IPT) was assessed using Morisky Medication Adherence Scale, and all the ADRs reported were assessed for clinical pattern, causality, severity, and preventability.

Results:

Out of 122 reports, a total of 37 reactions occurred in 24 people. Rash and itching are the majorly reported ADRs, followed by headache and giddiness. According to the WHO causality assessment scale, 21 (87.5%) of the reported cases were probable and 3 (12.5%) were possibly related to suspected medication. Major ADRs were mild (91.6%) according to the severity assessment done by Modified Hartwig and Siegel Scale.

Conclusions:

Medication adherence is good (61.4%) in the majority of the population (PLHIV), in spite of mild ADRs. The majority of ADRs are mild in nature and the necessity for dechallenge did not arise. Most of the ADRs come under probable, and the majority of them are preventable by proper periodic assessment.
Rational Prescribing and Deprescribing of Antihypertensive Medications in Older People, Part 2
Authors: Russell Patrick , Thompson Campbell , Mangoni Arduino A.
Published: March 2023

The evidence is strong in favor of blood pressure (BP) control in robust older people as a way to reduce morbidity and mortality in the same way that treatment improves the lives of middle-aged people. Expert editorials have been written over the last five decades persuasively arguing
for or against more intensive treatment of older people with hypertension, supported by the specificity of (then) contemporaneous randomized controlled trials (RCTs) or the generalizability of observational studies. But there are limitations.First, there has always been such a thing as
too low. Early epidemiological studies showed an upward inflection in mortality curves that resemble a slanted letter J. Second, certain complex older people encountered routinely in a clinic, pharmacy, or nursing facility were often excluded from the RCTs showing benefit from intensive
BP control. Cohort studies of these complex people showed a different truth, that the point of “too low” might move up and that BP targets for adults might be too low for select older people. Not all older people are the same. Some are burdened by frailty superimposed on cardiovascular
disease and a limited life-expectancy. It is one thing not to start BP-lowering medications for this patient; it is an entirely different matter to stop.
Strajk w Stoczni Szczecińskiej im. Adolfa Warskiego po 13 grudnia 1981 roku
Authors: Siedziako Michał
Published: March 2023

Po wprowadzeniu stanu wojennego na terenie całej Polski wybuchły strajki. Kluczowym ośrodkiem oporu na Pomorzu Zachodnim i jednym z istotnych w skali kraju była kolebka szczecińskiej Solidarności – Stocznia im. Adolfa Warskiego. Na jej terenie po 13 grudnia 1981 roku ukonstytuował się Międzyzakładowy Komitet Strajkowy, któremu przewodzili Mieczysław Ustasiak i Andrzej Milczanowski. Władzom zależało na jak najszybszym stłumieniu protestów. W nocy z 14 na 15 grudnia do zakładu wkroczyły oddziały wojska i milicji; kilkadziesiąt osób zostało aresztowanych. Członkowie kierownictwa strajkowego zostali następnie postawieni przed sądem wojskowym w Bydgoszczy. W pokazowym procesie część z nich w marcu 1982 roku skazano na kary pozbawienia wolności (najwyższy wyrok opiewał na pięć lat) i praw publicznych. Strajk w stoczni, choć pozbawiony przywództwa, był kontynuowany w formie zmianowej do 18 grudnia, kiedy władze, nie mogąc poradzić sobie z rozwojem sytuacji, zawiesiły działalność zakładu oraz przystąpiły do zwolnień i weryfikacji załogi.

Strike at the Szczecin Adolf Warski Shipyard after 13 December 1981

After martial law was imposed, strikes broke out all over Poland. The cradle of Solidarity in Szczecin—the Adolf Warski Shipyard, was the key centre of resistance in Western Pomerania and one of significance in all of Poland. After 13 December 1981, the Inter- -Enterprise Strike Committee was established there, spearheaded by Mieczysław Ustasiak and Andrzej Milczanowski. The authorities wanted to suppress the protests as quickly as possible. On the night of 14–15 December, army troops and police (MO) units entered the plant; several dozen people were arrested. The members of the strike leadership were subsequently brought before a military court in Bydgoszcz. In a show trial in March 1982, some of them were sentenced to imprisonment (the highest sentence was five years) and loss of civil rights. Although deprived of leadership, the strike at the Shipyard continued in shifts until 18 December, when the authorities, unable to cope with how the situation unfolded, suspended the plant’s operations and began to lay off and vet the workforce.
Internowani działacze NSZZ „Solidarność” z województwa pilskiego w ośrodkach odosobnienia we Wronkach, Gębarzewie, Kwidzynie i Wierzchowie Pomorskim
Authors: Wąsowicz Jarosław
Published: March 2023

Artykuł omawia losy działaczy Solidarności z województwa pilskiego internowanych w stanie wojennym. Ogółem w okresie od 13 grudnia 1981 do 1 września 1982 roku na tym terenie internowano 50 działaczy Solidarności, których przetrzymywano we Wronkach, Gębarzewie, Kwidzynie i Wierzchowie Pomorskim. W tym gronie znalazły się również dwie kobiety: Elżbieta Kaczmarek z Chodzieży oraz Barbara Oroń z Wałcza. Wśród internowanych było 25 działaczy z Piły, siedmioro z Chodzieży, sześcioro z Wałcza, po czterech z Trzcianki i Czarnkowa, po jednym ze Złotowa, Szamocina, Walkowic i Wągrowca. Przynależeli oni do trzech regionów związkowych: Województwa Pilskiego, Pomorza Zachodniego (Wałcz) i Wielopolski (Wągrowiec).

Interned NSZZ “Solidarność” Activists from Piła Voivodeship in the Internment Centres in Wronki, Gębarzów, Kwidzyn, Wierzchowo Pomorskie

The article discusses the fate of “Solidarność” activists from Piła voivodeship interned during the martial law. In the period from 96 Wolność i Solidarność | nr 13 JAROSŁAW WĄSOWICZ 13 Dec 1981 to 1 Nov 1982 on the area of this voivodeship, 50 “Solidarność” activists were interned, who were kept in Wronki, Gębarzów, Kwidzyn and Wierzchowo Pomorskie. In this group there were also two women: Elżbieta Kaczmarek from Chodzież and Barbara Oroń from Wałcz. Among the internees there were 25 activists from Piła, 7 from Chodzież, 6 from Wałcz, 4 from Trzcianka, 1 from Złotów, 1 from Szamocin, 1 from Walkowice, 1 from Wągrowiec. They were a part of three regions within the Union: Piła Voivodeship, West Pomerania (Wałcz), Greater Poland (Wągrowiec).
Władza liter. Polskie procesy modernizacyjne a awangarda
Authors: Rakoczy Marta
Published: March 2023

Nauka pisania i czytania miała stanowić w II RP narzędzie z jednej strony modernizacji i emancypacji klas niewykształconych, z drugiej ‒ tworzenia zestandaryzowanej językowo kultury narodowej. W wielu ówczesnych dyskursach analfabetyzm utożsamiany był z „ciemnotą” i zagrożeniem dla życia społecznego, słowo pisane zaś ‒ z cywilizacją i partycypacją w życiu publicznym. W książce Władza liter zastanawiam się, jak przekonania te były przetwarzane i parodiowane przez polską awangardę, zwłaszcza warszawskich futurystów. Czym na tle ówczesnych dyskursów psychologicznych i grafologicznych były awangardowe eksperymenty z pisaniem automatycznym? Dlaczego ortograficzne wybryki futurystów budziły w II RP ogromną panikę moralną i w ramach jakich dyskusji dotyczących polityki językowej były oceniane? Dlaczego projekty eugeniczne II RP poruszały problem analfabetyzmu i co oznaczało to dla sztuki? I dlaczego młodość, postęp oraz demokratyzacja kultury mogły się awangardzie kojarzyć z niszczeniem słowa drukowanego? Polska awangarda była formacją intelektualną, która zrozumiała konsekwencje kulturowe starych i nowych mediów i zaczęła systematycznie pytać o to, w jaki sposób przemiana praktyk komunikacyjnych może powodować przemianę społeczeństwa. Podjęta przez awangardę krytyka kultury wiodła przez krytykę języka, ta natomiast przez krytykę mediów. W swej książce chciałam pokazać, w jak złożonym polu kulturowym działy się jej eksperymenty i w jak trudnym kontekście dyskursywnym przyszło jej funkcjonować. Nie jest to zatem publikacja ściśle o awangardzie. To publikacja usiłująca przedstawić, jak złożoną, wymagającą i kuszącą nowymi nadziejami epoką było polskie międzywojnie.
Europa i jej profile znaczeniowe w chorwackich i serbskich dyskursach medialnych (2007–2017)
Authors: Mirocha Piotr
Published: March 2023

„Książka Piotra Mirochy jest monografią interdyscyplinarną, metodologicznie nawiązującą do językoznawstwa (zwłaszcza socjolingwistyki), kulturoznawstwa, historii, antropologii kulturowej, politologii i filozofii. Podstawę materiałową stanowi prawie 20 000 artykułów z dzienników chorwackich („Novi list”, „Večernji list”) i serbskich („Politika”, „Danas”). Stosując metodologię korpusową, Autor na podstawie tego materiału przeanalizował profile znaczeniowe Europy w chorwackich i serbskich dyskursach medialnych. […] Monografia powinna zainteresować przedstawicieli różnych nauk humanistycznych”. prof. em. dr hab. Tadeusz Lewaszkiewicz Instytut Filologii Polskiej UAM
Các mô hình hồi quy cơ bản trong quản trị kinh doanh
Authors: Ngàn Ma Thế
Published: March 2023

Hướng nghiên cứu định lượng trong quản trị kinh doanh tại Việt Nam do đang còn trong những bước đầu tiên hội nhập quốc tế nên vẫn còn thiếu sự hệ thống về phương pháp, tạo ra rào cản đáng kể cho các nhà nghiên cứu. Nhằm lấp vào khoảng trống nghiên cứu này, bài báo giới thiệu tới các đồng nghiệp và bạn đọc trong nước một số mô hình phân tích hồi quy cơ bản. Trong bài viết, tác giả áp dụng phương pháp tổng quan với tài liệu được chọn lọc chủ yếu từ nguồn Web of Science và một số sách báo đáng tin cậy khác. Kết quả nghiên cứu chỉ ra ba mô hình hồi quy cơ bản, gồm: tác động trực tiếp, tác động trung gian và tác động điều tiết. Mỗi mô hình được giới thiệu bao gồm khái niệm, phương trình hồi quy, các kỹ thuật kiểm định và ví dụ minh họa. Bài viết đóng góp vào những bước đầu tiên trong việc hệ thống hóa phương pháp nghiên cứu định lượng tại Việt Nam.
Các yếu tố ảnh hưởng đến tăng trưởng kinh tế tại vùng kinh tế trọng điểm phía Nam
Authors: Quyên Nguyễn Lê Hoàng Thụy Tố , Hường Ngô Thị Cẩm
Published: March 2023

Nghiên cứu này hướng đến việc tìm hiểu các yếu tố tác động đến tăng trưởng kinh tế của vùng kinh tế trọng điểm phía Nam. Dựa trên bộ dữ liệu của 08 tỉnh, thành phố thuộc vùng trong giai đoạn 2005 - 2019, thông qua các phương pháp ước lượng dữ liệu bảng như hồi quy gộp OLS, tác động cố định (FEM), tác động ngẫu nhiên (REM) và Feasible Generalized Least Square (FGLS). Sau khi tiến hành kiểm định và so sánh các mô hình này, FGLS được đánh giá là tối ưu nhất. Kết quả nghiên cứu cung cấp bằng chứng về vai trò của xuất khẩu, tỷ lệ dân số đô thị, giáo dục, khả năng phát triển công nghệ thông tin đối với tăng trưởng kinh tế của vùng. Phát hiện này là cơ sở cho các tỉnh, thành thuộc vùng kinh tế trọng điểm tập trung cải thiện các chính sách liên quan đến thương mại quốc tế và thu hút đầu tư trực tiếp nước ngoài; đẩy nhanh việc phát triển công nghệ thông tin; nâng cao chất lượng lao động và thúc đẩy quá trình đô thị hóa.
Reduction of Kummer surfaces modulo 2 in the non-supersingular case
Authors: Lazda Christopher , Skorobogatov Alexei
Published: March 2023

We obtain necessary and sufficient conditions for the good reduction of Kummer surfaces attached to abelian surfaces with non-supersingular reduction when the residue field is perfect of characteristic 2. In this case, good reduction with an algebraic space model is equivalent to good reduction with a scheme model, which we explicitly construct.

Comment: 31 pages, comments welcome!
Este é um mundo terrível, mas quero ver cada segundo dele
Authors: Andrade Pereira Aline
Published: March 2023

O trabalho tem por objetivo investigar o papel da distopia no imaginário contemporâneo, com foco na minissérie Years and Years. De forma específica, pretendemos pensar de que maneira a obra materializa o imaginário político atual. A hipótese é que este tipo de distopia se tornou um traço distintivo forte na narrativa audiovisual. A metodologia a ser utilizada é a análise de conteúdo qualitativa (BARDIN, 2000), aliada a uma adaptação da análise fílmica de conteúdo proposta por Penafria (2009). Tomamos “imaginário” a partir de Maffesoli (2001) e, para compreensão do imaginário político, utilizaremos as “constelações mitológicas” propostas por Girardet (1987), a saber: A Conspiração; O Salvador; A Idade de Ouro e A Unidade. A partir daí, estabelecemos categorias mais específicas que definem esse imaginário político que denominamos: Os Presidentes Eternos, A Idade das Trevas e Os Estrangeiros, que dialogam com as categorias de Girardet, mas também vão além.
Imaginários e LGBTQIAP+fobia em textualidades midiáticas
Authors: Oliveira Abouid Philippe , De Carvalho Carlos Alberto
Published: March 2023

Este artigo apresenta a mobilização dos imaginários como ferramenta metodológica para a apreensão da LGBTQIAP+fobia em textualidades midiáticas. Como corpus de análise, selecionamos dois vídeos publicados no YouTube do Canal das Bee durante o período eleitoral para a presidência brasileira que tratavam sobre a Ideologia de gênero e o Kit gay, duas polêmicas que tiveram a LGBTQIAP+fobia como chave operatória. Consideramos que os imaginários historicamente construídos sobre as homossexualidades contribuíram para provocar um sentimento de ameaça em relação às práticas não normativas de gênero, sexo e sexualidade que são acionadas por essas polêmicas. Como gesto de análise, as textualidades midiáticas podem contribuir para fazer emergir imaginários LGBTQIAP+fóbicos que atravessam os jogos de poder e as disputas de sentido que constituem a sociedade brasileira na segunda metade do século XXI.
Creating GUIs in Python for Digital Humanities Projects
Authors: Goodwin Christopher
Published: March 2023

In this lesson, you will use Qt Designer and Python to design and implement a simple graphical user interface and application to merge PDF files. This lesson also demonstrates how to package the application for distribution to other personal computers.
Результаты существования для функционально возмущенных дифференциальных уравнений дробного порядка с запаздыванием в банаховых пространствах
Authors: Helal M.
Published: March 2023

In this paper, we provide sufficient conditions for the existence of solutions of initial value problem, for perturbed partial functional hyperbolic differential equations of fractional order involving Caputo fractional derivative with state-dependent delay by reducing the research to the~search of the existence and the uniqueness of fixed points of appropriate operators. Our main result for this problem is based on a nonlinear alternative fixed point theorem for the~sum of a completely continuous operator and a contraction one in Banach spaces due to Burton and Kirk and a fractional version of Gronwall's inequality. We should observe the structure of the space and the properties of the~operators to obtain existence results. To our knowledge, there are very few papers devoted to fractional differential equations with finite and/or infinite constant delay on bounded domains. Many other questions and issues can be investigated regarding the existence in the space of weighted continuous functions, the uniqueness, the structure of the~solutions set and also whether or not the condition satisfied by the operators are optimal. This paper can be considered as a contribution in this setting case. Examples are given to illustrate this work.
On the Best Polynomials Approximation of Segment Functions
Authors: Трынин А.Ю.
Published: March 2023

Предложен алгоритм поиска многочлена наилучшего приближения для непрерывной многозначной сегментной функции, заданной на совокупности не пересекающихся отрезков $X=\big(\bigcup_{j_{1}=0}^{n_1}[a_{j_1},b_{j_1}]\big) \cup\big(\bigcup_{k=0}^n x_k\big)$ таких, что $\big(\bigcup_{j_{1}=0}^{n_1}[a_{j_1},b_{j_1}]\big) \cap\big(\bigcup_{k=0}^n x_k\big)=\varnothing$, где не пересекающиеся отрезки $[a_{j_1},b_{j_1}]$ и точки $x_k$ принадлежат ограниченному отрезку $[A,B]\subset \mathbb{R}$. Считаем, что функции $f_{1}$ и $f_{2}$ непрерывны на множестве $X$, и всюду на $X$ значение функции $f_{1}(x)$ не превосходит значение функции $ f_{2}(x)$. Оператор, ставящий в соответствие каждому $x\in X$ отрезок $[(x,f_{1}(x)),(x,f_{2}(x))]$, будем называть сегментной функцией ${\cal F} (x)$, заданной на $X$. В силу непрерывности функций $f_{1}$ и $f_{2}$ сегментная функция ${\cal F}$ является $h$-полунеперывным отображением сверху. Многочлен $P_{m}=\sum_{i=0}^{m}a_{i}x^{i}$ наилучшего приближения в метрике Хаусдорфа на множестве $X$ сегментной функции ${\cal F}$ с вектором коэффициентов $\vec{a}=(a_0,a_1,\dots,a_m)\in {\mathbb{R}^{m+1}}$ есть решение экстремальной задачи $\min_{\vec{a}\in {\mathbb{R}^{m+1}}}\max_{x\in X}\max(P_{m}(x)-f_{1}(x),f_{2}(x)-P_{m}(x)).$ Методами конструктивной теории функций показано, что для любых непрерывных на $X$ функций $f_{1}(x)\le f_{2}(x)$ существует многочлен наилучшего приближения в xаусдорфовой метрике $h$-полунепрерывной сверху на множестве $X$ сегментной функции ${\cal F} (x)$. Предложен алгоритм описания множества $Е$ коэффициентов~$\vec{a}$ многочленов наилучшего приближения сегментной функции. Получены необходимые и достаточные условия единственности многочлена наилучшего приближения сегментной функции. Приведены результаты численных экспериментов, реализованных с помощью предложенного алгоритма.
Убывание решения задачи коши при неограниченном возрастании времени дважды вырожденных параболических уравнений с демпфированием
Authors: Tedeev Al. F. , Tedeev An. F.
Published: March 2023

In this paper we study the large time behaviour of the solution and compactification of support to the Cauchy problem for doubly degenerate parabolic equations with strong gradient damping. Under the suitable assumptions on the structure of the equation and data of the problem we establish new sharp bound of solutions for a large time. Moreover, when the support of initial datum is compact we prove that the support of the solution contains in~the~ball with radius which is independent in~time variable. In the critical case of the behaviour of the damping term the support of the solution depends on time variable logarithmically for a sufficiently large time. The main tool of the proof is based on nontrivial use of cylindrical Gagliardo--Nirenberg type embeddings and recursive inequalities. The sup-norm estimates of the solution is carried out by modified version of the classical method of De-Giorgi--Ladyzhenskaya--Uraltseva--DiBenedetto. The approach of the paper is flexible enough and can be used when studying the Cauchy--Dirichlet or Cauchy--Neumann problems in domains with non compact boundaries.
EDITORIAL: HEALTH SCIENCES: UNLEASHING POTENTIALS, SHAPING THE FUTURE
Authors: MOHD FAHMI TENG NUR ISLAMI
Published: March 2023

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DEVELOPMENT OF AGRO-BASED NANOFILTERS TO CAPTURE SUSPENDED TITANIUM IN AIR
Authors:   National Institute of Occupational Safety and Health, JAMEN SHAHRULNIZAM , SHAMSUL HARUMAIN ZAKUAN AZIZI ,   International Islamic University Malaysia, ZAHABA MARYAM ,   International Islamic University Malaysia, DANIAL WAN HAZMAN ,   International Islamic University Malaysia, MOHD ARIS MOHD SHUKRI ,   Universiti Teknologi MARA, MOHD ZURAIDI SITI NURNAFISAH ,   International Islamic University Malaysia, IDRIS MOHD SYAHMI ,   International Islamic University Malaysia, WAN ZAIN WAN LUTFIL HADI ,   International Islamic University Malaysia, ABDUL HADI HAZRIN ,   International Islamic University Malaysia
Published: March 2023

Nanosilica and nanozeolite synthesised from rice husk (RH) were investigated for their potential to develop a low-cost nanofilter membrane as an alternative to replace nylon membrane used in the Nanoparticle Respiratory Deposition (NRD) sampler for capturing titanium dioxide (TiO2) nanoparticles suspended in the air. Due to its exceptional adsorption capacity to many inorganic materials, graphene oxide was also investigated for its potential to capture the TiO2 nanoparticles to compare its performance with the newly developed agro-based nanofilters. All nanofillers were developed by depositing the synthesised nanomaterials on a polyvinylidene fluoride (PVDF) membrane using the layer deposition method and characterised by Field Emission Scanning Microscopy/Energy Dispersive X-ray (FESEM-EDX) analysis. Each nanofilters developed were exposed to TiO2 nanoparticles for 15 minutes with an average airflow of 2.5 L/minutes and were compared with the conventional nylon membrane used in NRD. Among all nanofilters developed, nanozeolite filter (0.1% w/v) showed the highest concentration of Ti captured (81.7 μg/g) compared to nanosilica (56.7 μg/g) and graphene oxide (8.2 μg/g) filters. Interestingly, all developed nanofilters did not show any presence of Ti in their background levels, further suggesting its purity in capturing Ti nanoparticles in the air.
STUDY ON THE EXTRACTION OF BLACK SOLDIER FLY (HERMETIA ILLUCENS) LARVAE OIL BY USING MECHANICAL PRESS METHOD
Authors:   Universiti Teknologi MARA, ROZALI NURUL SAFFAREEN , MOHD ZAINUDDIN NUR AIN ,   Universiti Teknologi MARA, MOHD YATIM SITI ROHANA ,   Universiti Teknologi MARA, WAN RASDI WAN NURUL NADIAH ,   Universiti Malaysia Terengganu
Published: March 2023

This study investigates the optimisation of Black Soldier Fly oil extraction from different feeding sources. The larvae are fed a mixture of pasta-tobacco waste (MPT) and fish-ball sludge (FS). The mechanical press method is used to extract the oil. The results showed that the MPT-fed larvae had a higher weight at 0.088 ±0.001 g compared to 0.062 ± 0.002 g for larvae fed with FS. The feeding rates revealed that the higher the dose of the feed, the more weight the larvae gained. Meanwhile, GC-MS results show that the MPT substrate has a higher number of characterised fatty acids than the FS substrate, with three predominant fatty acids being lauric acid (43.69%), palmitic acid (16.15%) and linoleic acid (12.35%). Fourier-Transform Infrared spectroscopy (FTIR) analysis for both substrates reveals a similar high absorbance but High-Performance Liquid Chromatography (HPLC) analysis shows glutamic acid to be the most abundant amino acid in both substrates. Additionally, the regression analysis shows that moisture content and feeding rate is the most important parameter. Response Surface Methodology (RSM) determined that moisture content and feeding rates were the best parameters for oil yield.
Estimación del consumo de combustible en un vehículo Ford Explorer aplicando la técnica Ecodriving en la ciudad de Guayaquil
Authors: Vinicio Noroña Merchán Marco , Alexandra Jerez Mayorga Daniela , Mero Cindy Melissa Loor , Barrezueta Manuel Fernando Gómez
Published: March 2023

En la actualidad el incremento en el costo del combustible, el cambio climático, los problemas de salud por contaminación atmosférica y los problemas de carácter socioeconómico; que éstos acarrean han sido los principales motivantes para el desarrollo de alternativas para el ahorro energético. La gama de automóviles propulsado por gasolina son uno de los cuales tiene una mayor oportunidad de mejora en cuanto a eficiencia energética se refiere. Una estrategia de eficiencia es modificar el estilo de los conductores a un modo conocido como Ecodriving, que se puede aplicar a vehículos alimentados por gasóleo. El objetivo de este estudio es comparar el consumo de combustible en un motor de combustión interna por chispa, aplicando un modo de conducción normal y uno de conducción eficiente, en un vehículo Ford Explorer con un motor 2.3L I-4 TiVCT Turbo Ecoboost. Para ello se utiliza el método de investigación cuantitativo ya que, por medio de fijar una ruta de una distancia de 24 km de recorrido de ida y 26 km de recorrido de vuelta, que tiene una ruta de alto tráfico, cuenta con un gran número de semáforos a lo largo del trayecto y esta ruta se encuentra una variación de límites de velocidad en todo el trazado delimitado. Mediante el dispositivo OBII Azuga se obtiene varios parámetros que se registraran al aplicar un estilo de conducción normal y un estilo de conducción ecológica.  Los resultados obtenidos revelan que al aplicar un modo de conducción ecológica se reduce el consumo instantáneo de combustible obteniendo beneficios de ahorro de combustible en la ciudad de Guayaquil y mayor rendimiento por galón.
THE ROLE AND IMPORTANCE OF AUDIO-VISUAL AIDS IN TEACHING
Authors: BARSEGHYAN Liana
Published: March 2023

The given paper is an attempt to explore the role and importance of audio-visual aids in teaching. The choice of the topic is dictated by the rapid development of new technologies and their interference into educational process. The aim of the paper is to identify the most widespread types of audio-visual aids used in classroom. The practical purpose of the study is to help teachers to integrate efficiently some new classroom technology in teaching.
A CRITICAL ANALYSIS OF SPEECHES BY PRESIDENT VLADIMIR PUTIN AND PRESIDENT BARACK OBAMA CONCERNING THE CRIMEAN EVENTS
Authors: TCHAPARIAN Vicky
Published: March 2023

The present paper is an attempt to study the Ethos, Pathos, and Logos in President of Russian Federation Vladimir Putin’s speech on March 18, 2014 announcing the reunion of the Crimea with the Russian Federation, and President of the USA Barack Obama’s reaction to the issue two days later on March 20, 2014. The research focuses on how much these speeches have been expressive-emotive-evaluative and persuasive for their audiences, proceeding from statements put forward in Aristotle’s rhetorical theory, and taking into consideration the positive and negative impacts these speeches might have made on the listeners.
ՀԱՄԱՌՈՏ ԱՆԴՐԱԴԱՐՁ 20-ՐԴ ԴԱՐԻ ՀԱՅԵՐԵՆ-ԱՆԳԼԵՐԵՆ ԲԱՌԱՐԱՆԱԳՐՈՒԹՅԱՆԸ
Authors: ՍԱՐՈՒԽԱՆՅԱՆ Բելլա
Published: March 2023

Տվյալ հոդվածում ներկայացվում են անցած դարում սփյուռքում լույս տեսած և սփյուռքահայության մեջ հայերենի պահպանմանն ուղղված լավագույն բառարանները: Ուշադրության է արժանանում այն հանգամանքը, որ ժամանակի գործոնը մեծ դեր է խաղում բառարանագրության մեջ, քանզի նոր տեխնոլոգիաների և գիտությունների զարգացումն ու ստեղծումն ի հայտ են բերում նոր եզրույթներ` անհրաժեշտություն առաջացնելով ընթերցողին ևս իրազեկել նորարարությունների հայերեն համարժեքներին:
К ВОПРОСУ О СТАТУСЕ МЕСТОИМЕНИЙ КАК САМОСТОЯТЕЛЬНОЙ ЧАСТИ РЕЧИ
Authors: ЕРЗИНКЯН Елена
Published: March 2023

В статье рассматривается вопрос о месте местоимений в общей классификации частей речи. Исходя из морфологической и функциональной неоднородности входящих в этот класс слов, а также отсутствия некоторого единого общекатегориального значения, в статье поднят вопрос о нецелесообразности выделения местоимений как отдельной самостоятельной части речи.
Socio-Cultural Determinants of Parental Refusal for Childhood Vaccination: A Semantic and Latent Thematic Analysis
Authors: Zafar Maria , Khursheed Bushra , Zafar Saad , Riaz Muhammad Usman
Published: March 2023

Incomplete vaccination coverage is hazardous for the upcoming generations of a country. Child immunization against various vaccine-preventable diseases is a focus all over the world. The vaccination schedule information is a vital component of vaccination coverage, and its failure leads to incomplete immunization among newborns. Education, employment, and urban facilities are also essential for the complete immunization of a child. There is a significant difference in vaccination coverage due to all these factors. The main objective of this study was to explore the reasons for incomplete vaccination coverage due to the factors mentioned earlier, like why the information gap is there and what makes uneducated parents vulnerable to incomplete immunization, and why the urban-rural disparity exists regarding complete vaccination coverage in Punjab, Pakistan. The researchers conducted in-depth interviews of the mothers having at least one child from 1-2 years of age to explore factors responsible for incomplete vaccination coverage. Insufficient vaccination coverage was related to perceived adverse effects, cultural settings, information gap, lifestyle, parental employment and occupation, the risk to the immune system, risk perception about the disease, perception of efficacy, and misconception about vaccination. In-depth interviews proved vital for exploring underlying reasons for incomplete vaccination coverage. The current study explicates the profound views of respondents on why they refuse vaccination for their children. There should be a rigorous focus on increasing awareness of vaccination.
Clinical significance of anti-DFS70 in immunoinflammatory rheumatic diseases (review)
Authors: Panafidina T. A. , Verizhnikova Zh. G. , Avdeeva A. S. , Popkova T. V. , Nasonov E. L.
Published: March 2023

The relevance of the problem of immunoinflammatory rheumatic diseases (IIRD) for modern medicine is determined by their high prevalence in the population, the difficulty of early diagnosis, the rapid development of disability and poor life prognosis. Recent data on the significance of anti-DFS70 have opened up new possibilities for optimizing the step-by-step diagnosis of IIRD. The detection of these antibodies can help in the interpretation of a positive result for antinuclear antibodies (ANA) by indirect immunofluorescence assay on HEp-2 cells (IIFA-HEp-2) in the absence of autoantibodies specific for IIRD. Detection of anti-DFS70 in antinuclear factor (ANF) seropositive patients without clinical and/or serological markers characteristic of a certain disease from the IIRD group can be considered as a potential marker that excludes this group of diseases.
Damage to extracranial arteries in giant cell arteritis according to PET/CT
Authors: Filatova E. E. , Bulanov N. M. , Meshkov A. D. , Borodin O. O. , Smitienko I. O. , Chachilo E. V. , Novikov P. I. , Moiseev S. V.
Published: March 2023

The aim of the study was to assess the incidence of arterial lesions of various localizations in patients with giant cell arteritis (GCA) according to positron emission and computed tomography (PET/CT) with 18F-fluorodeoxyglucose (18F-FDG).Methods. Patients over 50 years of age diagnosed with GCA (with or without polymyalgia rheumatica) were included in a retrospective study. Damage to extracranial arteries was assessed based on the accumulation of 18F-FDG in the walls of large vessels according to PET/CT data.Results. The study included 47 patients, 14 (30%) men and 33 (70%) women, with a median age of 65 [57; 68] years. In 32 (68%) patients, 18F-FDG-PET/CT was performed before the start of therapy with glucocorticosteroids (GCS), in 15 (32%) after the start of treatment. In 40 (91%) patients, signs of damage to extracranial vessels of various localization were revealed, most often in the thoracic and abdominal aorta (72% and 64%, respectively).Conclusions. According to 18F-FDG-PET/CT data, in most patients with GCA, not only the arteries of the head and neck, but also vessels of other localization are involved in the pathological process.
Variants of impingement syndrome of the shoulder joint
Authors: Nesterenko V. A. , Karateev A. E. , Arkhipov S. V. , Makarov M. A. , Makarov S. A. , Bialik E. I. , Stadnik V. I. , Bimbaeva A. D. , Bialik V. E. , Zelenov V. A. , Roskidailo A. A. , Naryshkin E. A. , Khramov A. E.
Published: March 2023

Pain in the shoulder joint is one of the most common reasons for seeking medical help associated with the pathology of the musculoskeletal system. The most common disease in this area that causes chronic pain is impeachment syndrome (IS) of the rotator muscles of the shoulder. The domestic literature describes in sufficient detail surgical and conservative approaches for lesions of the shoulder joint, but there are only a few publications on the types of IS. This review is devoted to the description of all occurring types of compression of the tendons of the muscles of the rotator cuff of the shoulder joint within the framework of IS.
Chronic and opportunistic infections in patients with immuno-inflammatory rheumatic diseases: screening and prevention issues (based on the materials of the EULAR recommendations)
Authors: Belov B. S. , Gridneva G. I. , Aronova E. S. , Nasonov E. L.
Published: March 2023

At the present stage of development of rheumatology, much attention is paid to the problem of comorbid infections, which have a significant impact on mortality and mortality, especially in immuno-inflammatory rheumatic diseases (IIRD). The active introduction into clinical practice of innovative drugs, the action of which is aimed at specific components of the pathogenesis of IIRD, has led to an increase in the risk of developing infections of various nature and localization, including chronic and opportunistic (COI). This article analyzes the recommendations for screening and prevention of COI in adult patients with acute respiratory infections, proposed in November 2022 by experts of the European Alliance of Rheumatology Associations (EULAR). It is noted that these recommendations should be considered through the prism of national guidelines that take into account regional risk factors, features of the course, diagnosis, therapy and prevention of СOI. At the same time, it seems absolutely justified to periodically review screening and preventive procedures as new scientific data accumulate. Despite the importance of a multidisciplinary approach and the need for close cooperation with doctors of other specialties, the EULAR working group emphasizes the central role of a rheumatologist in the management of patients with HOI that occur against the background of IIRD and are associated with the received anti-rheumatic therapy.
To the 95th anniversary of the Russian rheumatological service
Authors: Balabanova R. M. , Dubinina T. V. , Nasonov E. L.
Published: March 2023

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Clinical and immunological variants of ANCA-associated systemic vasculitis: a look at the pulmonary fibrosis in microscopic polyangiitis with anti-myeloperoxidase antibodies and rheumatoid factor. Literature review and own observation
Authors: Beketova T. V. , Golovina O. A. , Avdeeva A. S.
Published: March 2023

Depending on the epitope specificity of antineutrophil cytoplasmic antibodies (ANCA) and the presence or absence of a granulomatous inflammation. Patients with ANCA-associated vasculitis (AAV) show variability in clinical manifestations and prognosis depending on the epitope specificity of ANCA and the presence or absence of granulomatous inflammation. In this regard, it is important to identify the clinical and immunological phenotypes of AAV and a personalized approach to treatment. Microscopic polyangiitis (MPA) with antibodies to myeloperoxidase (aMPO) has a relatively high incidence of lung involvement and pulmonary fibrosis. We present our own clinical case of pulmonary fibrosis in MPA with aMPO and rheumatoid factor. Literature data are discussed. In cases of early arthritis and interstitial pneumonia, the possibility of AAV should be considered, a detailed examination is necessary to identify pathognomonic signs of AAV, including asymptomatic ones. Before prescribing immunosuppressants, the epitope specificity of ANCA should be determined. Treatment with rituximab, mycophenolate mofetil and nintedanib is discussed.
Molecular mechanisms of the development of the phenomena of peripheral and central sensitization in rheumatoid arthritis
Authors: Potapova A. S.
Published: March 2023

Modern tactics for the treatment of rheumatoid arthritis is aimed at achieving remission or low activity of the disease, the maximum elimination of the manifestations of the disease and the restoration of physical and social activity of patients. At the same time, despite the wide range of the most modern pathogenetic agents, a good therapeutic response can’t be obtained in all cases. A difficult problem is the so-called rheumatoid arthritis RA (difficult to treat), in which two or more sequentially prescribed genetically engineered biological drugs or JAK inhibitors are ineffective. One of the important factors negatively affecting the outcome of RA treatment are functional disorders of the nociceptive system, such as peripheral and central sensitization. These phenomena, associated with persistent activation of nociceptive neurons and the development of nociplastic changes, are caused by systemic autoimmune inflammation and the influence of various cytokines and chemokines on the neuronal membrane. This review considers the molecular biological aspects of the formation of peripheral and central sensitization in RA, with a separate analysis of the pathogenetic role of individual interleukins.
The effectiveness of the use of various methods of shock wave therapy in the complex treatment of athletes with lateral epicondylitis
Authors: Ivanov M. V. , Samoylov A. S. , Pustovoyt V. I.
Published: March 2023

The purpose of the study: to evaluate the effectiveness of various methods of shock wave therapy in the complex treatment of athletes with lateral epicondylitis.

Materials and methods: the study involved 122 people. with a diagnosis of Lateral epicondylitis, aged 20 to 45 years, of which 55 (45.1 %) women and 67 (54.9 %) men. All patients were divided into 4 groups: a control group, which included 28 people who underwent standard treatment, and 3 groups, a total of 94 people, who underwent shock wave procedures using various methods against the background of standard treatment. The examination included the collection of complaints, anamnesis, physical examination, assessment of the function of the upper limb using the QuickDASH questionnaire, assessment of tennis elbow using the PRTEE questionnaire, carpal dynamometry was performed on a MEGEON-34090 dynamometer, and statistical methods. All studies were conducted before, after treatment, as well as after 3 weeks and 1 month. after treatment.

Results: shockwave therapy applied to tendons, flexors of the hand, and triceps brachii outperformed shockwaves to tendons or tendons and flexors of the hand in terms of Upper Limb Functional Activity (DASH) (p < 0,05) and score tennis elbow (PRTEE) (p < 0,05) after 3 weeks and after 1 month after treatment.

Conclusion: reducing the severity of pain syndrome and functional disorders of the upper limb when performing various types of activities, when conducting shock wave therapy on the area of the tendons, flexor muscles of the hand and the triceps muscle of the shoulder indicates a faster recovery of the functions of the upper limb, which is especially important for athletes.
Blood fluidity during physical exertion of various types
Authors: Grigorjeva M. E. , Sorokoletov S. M. , Korobovsky A. V. , Lyapina L. A.
Published: March 2023

This paper presents data from the literature and own results on the study of blood fluidity (or rheological properties) when performing physical exercises. It is shown that the rheology of blood depends on the functional state of the haemostasis system. It has been established that in the physiological state of the organism, physical exertion of any strength can lead to changes in the reactions of primary and plasma haemostasis and, accordingly, the rheological properties of blood. The review describes the study of factors related to blood flow in humans and animals before and after physical exercise (running, swimming, etc.) in the normal physiological state of the organism, with overstrain and with certain types of pathology (cardiovascular and metabolic diseases). Data on blood flow in conditions of physical activity restriction are presented. Special attention is paid to the corrective role of physical exercises on the rheology (fluidity) of blood in violation of homeostasis of the organism. Possible mechanisms of action of physical exertion on blood flow are considered.