bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis of 4,N‐Diaryl‐2,7,7‐trimethyl‐5‐oxo‐1,4,5,6,7,8‐hexahydro‐3‐quinolinecarbox amides.
Authors: Gein V. L. , Kazantseva M. I. , Kurbatova A. A.
Published: March 2012

The title compounds (IV) (11 examples) are obtained in an four‐component one‐pot reaction of dimedone, N‐aryl‐substituted acetoacetic acid amides, aryl aldehydes, and ammonium acetate.
ChemInform Abstract: A Method for the Reductive Scission of Heterocyclic Thioethers.
Authors: Graham Thomas H. , Liu Wensheng , Shen Dong‐Ming
Published: March 2012

A chemoselective and generally high‐yielding method for the reductive scission of heterocyclic thioethers (I) is described.
ChemInform Abstract: Synthesis of Libraries of Quinoxalines Through Eco‐Friendly Tandem Oxidation—Condensation or Condensation Reactions.
Authors: Paul Susmita , Basu Basudeb
Published: March 2012

Condensation of α‐dicarbonyl compounds, α‐hydroxy ketones, and α‐bromo ketones with 1,2‐diamines is efficiently promoted by KF on basic alumina to give quinoxalines and pyrazines in good yields.
ChemInform Abstract: BOP‐Mediated One‐Pot Synthesis of C5‐Symmetric Macrocyclic Pyridone Pentamers.
Authors: Du Zhiyun , Ren Changliang , Ye Ruijuan , Shen Jie , Maurizot Victor , Lu Yujin , Wang Jian , Zeng Huaqiang
Published: March 2012

A greener, more cost‐effective and time‐saving method for the synthesis of the title compounds (II) is developed.
ChemInform Abstract: Palladium‐Catalyzed Enantioselective Desymmetrization of Silacyclobutanes: Construction of Silacycles Possessing a Tetraorganosilicon Stereocenter.
Authors: Shintani Ryo , Moriya Kohei , Hayashi Tamio
Published: March 2012

A new method to prepare chiral organosilanes is reported.
ChemInform Abstract: Solvent‐Induced Selectivity Switching: Intermolecular Allylsilylation, Arylsilylation, and Silylation of Alkynes over Montmorillonite Catalyst.
Authors: Motokura Ken , Matsunaga Shigekazu , Miyaji Akimitsu , Yashima Tatsuaki , Baba Toshihide
Published: March 2012

Reactions of alkynes (I) with allylsilane (II), catalyzed by H+‐montmorillonite, are studied in various solvents.
ChemInform Abstract: Palladium‐Catalyzed Cross‐Coupling of PhSeSnBu3 with Aryl and Alkyl Halides in Ionic Liquids: A Practical Synthetic Method of Diorganyl Selenides.
Authors: Zhao Hong , Hao Wenyan , Xi Zhiwen , Cai Mingzhong
Published: March 2012

The Pd‐catalyzed reaction of phenylselenylstannane (II) with a wide variety of aromatic and aliphatic iodides and bromides proceeds smoothly in a room temperature ionic liquid to give the corresponding phenyl organyl selenides in good yields.
ChemInform Abstract: New Polyene Macrolide Family Produced by Submerged Culture of Streptomyces durmitorensis.
Authors: Flieger Miroslav , et al. et al.
Published: March 2012

A new polyene macrolide, closely related to the pentaene macrolide antibiotic roflamycoin, is isolated from both fermentation broth and biomass of Streptomyces durmitorensis wild‐type strain MS405.
ChemInform Abstract: Ionothermal Synthesis of Polyoxometalates
Authors: Ahmed Ejaz , Ruck Michael
Published: March 2012

Review: 20 refs.
ChemInform Abstract: Small Adsorbate‐Assisted Shape Control of Pd and Pt Nanocrystals
Authors: Chen Mei , Wu Binghui , Yang Jing , Zheng Nanfeng
Published: March 2012

Review: 120 refs.
ChemInform Abstract: Solvothermal Synthesis of Cerium Oxides
Authors: Walton Richard I.
Published: March 2012

Review: 101 refs.
ChemInform Abstract: An Improved Thermodynamic Modeling of the Fe—Cr System Down to Zero Kelvin Coupled with Key Experiments
Authors: Xiong Wei , Hedstroem Peter , Selleby Malin , Odqvist Joakim , Thuvander Mattias , Chen Qing
Published: March 2012

Review: 55 refs.
ChemInform Abstract: Recent Advances in Ring‐Forming Reactions of Donor—Acceptor Cyclopropanes
Authors: Mel'nikov Mikhail Ya. , Budynina Ekaterina M. , Ivanova Olga A. , Trushkov Igor V.
Published: March 2012

Review: 55 refs.
ChemInform Abstract: Recent Advances in the Chemical and Enzymatic Chondroitin Sulfate Synthesis
Authors: Vibert Aude , Jacquinet Jean‐Claude , Lopin‐Bon Chrystel
Published: March 2012

Review: 24 refs.
ChemInform Abstract: Mannuronic Acids: Reactivity and Selectivity
Authors: Codee Jeroen D. C. , Walvoort Marthe T. C. , de Jong Ana‐Rae , Lodder Gerrit , Overkleeft Herman S. , van der Marel Gijsbert A.
Published: March 2012

Review: 41 refs.
ChemInform Abstract: Benzimidazole: A Medicinally Important Heterocyclic Moiety
Authors: Narasimhan Balasubramanian , Sharma Deepika , Kumar Pradeep
Published: March 2012

Review: 50 refs.
ChemInform Abstract: Cyclic Electron Delocalization in Pericyclic Reactions
Authors: Arrieta Ana , de Cozar Abel , Cossio Fernando P.
Published: March 2012

Review: 129 refs.
ChemInform Abstract: The Physiological and Medicinal Potential Pyrimidines & Different Scheme to Synthesize Pyrimidine Heterocycles
Authors: Modi Vishal S. , Basuri Tara Shankar
Published: March 2012

Review: 50 refs.
ChemInform Abstract: Palladium Nanoparticles as Efficient Catalysts for Suzuki Cross‐Coupling Reactions
Authors: Perez‐Lorenzo Moises
Published: March 2012

Review: 30 refs.
ChemInform Abstract: Modelling the Effect of Solvents on Carbohydrates
Authors: Spiwok Vojtech , French Alfred D.
Published: March 2012

Review: 47 refs.
ChemInform Abstract: Oxidation of Chemical Compounds: Kinetics and Mechanistic Approach
Authors: Gour S. R. , Dhobal B. S. , Hussain Sayyed , Farooqui Mazahar
Published: March 2012

Review: 101 refs.
ChemInform Abstract: Self‐Assembling Peptide Scaffolds for Regenerative Medicine
Authors: Matson John B. , Stupp Samuel I.
Published: March 2012

Review: 93 refs.
ChemInform Abstract: Solid Acids as Electrolyte Materials for Proton Exchange Membrane (PEM) Electrolysis: Review
Authors: Goni‐Urtiaga Asier , Presvytes Dimitrios , Scott Keith
Published: March 2012

Review: 140 refs.
ChemInform Abstract: Development and Evaluation of Porous Materials for Carbon Dioxide Separation and Capture
Authors: Bae Youn‐Sang , Snurr Randall Q.
Published: March 2012

Review: 92 refs.
ChemInform Abstract: Commemorating Two Centuries of Iodine Research: An Interdisciplinary Overview of Current Research
Authors: Kuepper Frithjof C. , et al. et al.
Published: March 2012

Review: 282 refs.
ChemInform Abstract: Fossil Fuel Decarbonization: In the Quest for Clean and Lasting Fossil Energy
Authors: Muradov Nazim Z.
Published: March 2012

Review: 195 refs.
ChemInform Abstract: The Light‐Emitting Electrochemical Cell: Utilizing Ions for Self‐Assembly and Improved Device Operation
Authors: Edman Ludvig
Published: March 2012

Review: 127 refs.
ChemInform Abstract: Mechanistic Issues in Fischer—Tropsch Catalysis
Authors: van Santen R. A. , Ciobica I. M. , van Steen E. , Ghouri M. M.
Published: March 2012

Review: 113 refs.
ChemInform Abstract: Dynamic Recovery in Silicate‐Apatite Structures under Irradiation and Implications for Long‐Term Immobilization of Actinides.
Authors: Weber William J. , Zhang Yanwen , Xiao Haiyan , Wang Lumin
Published: March 2012

Irradiation‐induced amorphization and recrystallization of Ca2La8(SiO4)6O2 and Sr2Nd8(SiO4)6O2 with the apatite structure are investigated to predict their long‐term behavior as host phases for immobilization of actinide elements from the nuclear fuel cycle.
ChemInform Abstract: UV Nonlinear Optical Crystal Ba2[B6O9(OH)4] Featuring Unique Chiral Layers with a New B18O42 Circle Based on BO3 and BO4 Units.
Authors: Wang Li , Pan Shilie , Chang Lixian , Hu Jianyang , Yu Hongwei
Published: March 2012

The new title compound is hydrothermally synthesized from a mixture of Ba(NO3)2, H3BO3, and LiOH in H2O (autoclave, 200 °C, 3 d, 85% yield).
ChemInform Abstract: Spectroscopic Studies of Sulfite‐Based Polyoxometalates at High Temperature and High Pressure.
Authors: Quesada Cabrera Raul , Firth Steven , Blackman Christopher S. , Long De‐Liang , Cronin Leroy , McMillan Paul F.
Published: March 2012

The eclipsed (α) and staggered (β) forms of (Pen4N)4 [Mo18O54(SO3)2]·MeCN (Pen: ‐(CH2)4‐Me) are characterized by a combination of IR, Raman, and visible spectroscopy at high temperature and high pressure.
ChemInform Abstract: The Structure and Luminescence Properties of Green Ca3Al2O6:Bi3+ Phosphors.
Authors: Ju Haidong , Deng Weiping , Wang Baoling , Liu Jie , Tao Xutang , Xu Shiqing
Published: March 2012

The title phosphors are prepared by solid state reaction of CaCO3, Al2O3, and Bi2O3 (air, 1300 °C, 6 h, alumina crucibles).
ChemInform Abstract: Crystal and Magnetic Structures and Magnetic Properties of Selenate Containing Natrochalcite, AIM2II(H3O2) (SeO4)2 Where A: Na or K and M: Mn, Co, or Ni.
Authors: Maalej Wassim , Vilminot Serge , Andre Gilles , Elaoud Zakaria , Mhiri Tahar , Kurmoo Mohamedally
Published: March 2012

Compounds (IIIb,c) and (Vb) crystallize with the natrochalcite‐type structure in the monoclinic space group C2/m with Z = 2 (single crystal XRD for the Ni‐ and powder XRD for the Mn‐compound).
ChemInform Abstract: Phase Stability and Oxygen Nonstoichiometry of Highly Oxygen‐Deficient Perovskite‐Type Oxides: A Case Study of (Ba,Sr)(Co,Fe)O3‐δ.
Authors: Mueller David N. , De Souza Roger A. , Yoo Han‐Ill , Martin Manfred
Published: March 2012

The phase stability and oxygen nonstoichiometry of Ba0.5Sr0.5Co0.8Fe0.2 O3‐δ (BSCF5582) is investigated using thermogravimetry (TG) and coulometric titration (CT).
ChemInform Abstract: Studies on the Chemistry of [Cd(NH3)4](MnO4)2. A Low Temperature Synthesis Route of the CdMn2O4+x Type NOx and CH3SH Sensor Precursors.
Authors: Kotai Laszlo , et al. et al.
Published: March 2012

[Cd(NH3)4](MnO4)2 (I) is synthesized from an aqueous solution of CdSO4, NH3, and NaMnO4 at 0 °C (86% yield).
ChemInform Abstract: Diastereoselective Synthesis of Enantiopure Homopropargylic N‐tert‐Butylsulfinylamines.
Authors: Cyklinsky Mathieu , Botuha Candice , Chemla Fabrice , Ferreira Franck , Perez‐Luna Alejandro
Published: March 2012

The propargylation of N‐tert‐butylsulfonylimines (I) and (IV) with allenylzinc reagent (II), generated in situ, proceeds with excellent regio‐ and diastereoselectivity to give alkynes (III) and (V), resp., as highly preferred products.
ChemInform Abstract: Cu(I)‐Catalyzed Tandem Benzyldiazoester Coupling with Terminal Alkyne—Allene Formation—Michael Reaction: Application to the Syntheses of Oxa and Azacycles.
Authors: Kumaraswamy Gullapalli , Jayaprakash Neerasa , Balakishan Guniganti
Published: March 2012

A diastereoselective, simple, and practical procedure for the title synthesis is presented.
ChemInform Abstract: Radical‐Mediated Intramolecular C—C Bond Formation and the Deoxygenation of Alcohols under Solvent‐Free Conditions with Tributyl Methyl Ammonium Hypophosphite.
Authors: Lee Eun Hwa , Cho Dae Hyan , Satyender Apuri , Jang Doo Ok
Published: March 2012

The use of AHP as hydrogen donor under radical conditions allows the cyclization of iodoacetals (I).
ChemInform Abstract: Facile Synthesis of Hierarchical Core—Shell Fe3O4@MgAl—LDH@Au as Magnetically Recyclable Catalysts for Catalytic Oxidation of Alcohols.
Authors: Mi Fei , Chen Xitao , Ma Yuewen , Yin Shuangtao , Yuan Fanglong , Zhang Hui
Published: March 2012

The title catalyst exhibits excellent activity for the oxidation of 1‐phenylethanol.
ChemInform Abstract: Graphene Oxide: An Efficient and Reusable Carbocatalyst for Aza‐Michael Addition of Amines to Activated Alkenes.
Authors: Verma Sanny , Mungse Harshal P. , Kumar Neeraj , Choudhary Shivani , Jain Suman L. , Sain Bir , Khatri Om P.
Published: March 2012

Graphene oxide is found to be a highly efficient organocatalyst for the aza‐Michael addition of amines (I) to activated alkenes (II) and (IV).
ChemInform Abstract: A Manganese/Copper Bimetallic Catalyst for C—N Coupling Reactions under Mild Conditions in Water.
Authors: Teo Yong‐Chua , Yong Fui‐Fong , Lim Gina Shiyun
Published: March 2012

A low cost catalytic combination of MnF2, CuI and trans‐1,2‐diaminocyclohexane is developed to allow the regioselective N‐arylation of different N‐heterocycles.
ChemInform Abstract: Kumada Coupling of Aryl, Heteroaryl, and Vinyl Chlorides Catalyzed by Amido Pincer Nickel Complexes.
Authors: Liu Ning , Wang Zhong‐Xia
Published: March 2012

Both NPO and PON promote the cross‐coupling of aryl, heteroaryl, and vinyl chlorides with aromatic Grignard reagents.
ChemInform Abstract: InI3/Me3SiI‐Catalyzed Direct Alkylation of Enol Acetates Using Alkyl Acetates or Alkyl Ethers.
Authors: Onishi Yoshiharu , Nishimoto Yoshihiro , Yasuda Makoto , Baba Akio
Published: March 2012

An environmentally friendly catalytic system for the title alkylation is presented.
ChemInform Abstract: Cobalt Oxide Supported Gold Nanoparticles as a Stable and Readily‐Prepared Precursor for the in situ Generation of Cobalt Carbonyl Like Species.
Authors: Hamasaki Akiyuki , Muto Akiko , Haraguchi Shingo , Liu Xiaohao , Sakakibara Takanori , Yokoyama Takushi , Tokunaga Makoto
Published: March 2012

The Co species is an efficient catalyst for the alkoxycarbonylation of epoxides and alcohols and the intra‐ and intermolecular Pauson—Khand reaction.
ChemInform Abstract: An Efficient and Expeditious Fmoc Protection of Amines and Amino Acids in Aqueous Media.
Authors: Gawande Manoj B. , Branco Paula S.
Published: March 2012

The reaction is conducted under environmentally benign conditions.
ChemInform Abstract: Stereoselective γ‐Olefination of Substituted Cyclobutenediones by Organocatalysis.
Authors: Beesu Mallesh , Periasamy Mariappan
Published: March 2012

Alkyl‐substituted cyclobutenediones react with aromatic aldehydes in the presence of catalytic amounts of pyrrolidine to afford alkenyl‐substituted derivatives (III) and (V) stereoselectively.
ChemInform Abstract: Reactivity of Mixed Organozinc and Mixed Organocopper Reagents. Part 6. Nickel‐Catalyzed Coupling of Methylarylzincs with Primary Alkyl Halides: An Atom‐Economic Aryl—Alkyl Coupling.
Authors: Pekel Oezgen Oemuer , Erdik Ender
Published: March 2012

Under optimized conditions, the method gives the products (III) in moderate yields.
ChemInform Abstract: Homogeneous Silver(I) Salts and Heterogeneous Ag3PW12O40‐Catalyzed Intermolecular Allylation of Arenes with Allylic Alcohols.
Authors: Chen Guo‐Qiang , Xu Zhen‐Jiang , Chan Sharon Lai‐Fung , Zhou Cong‐Ying , Che Chi‐Ming
Published: March 2012

AgOTf is reported to be effective for the allylation of electron‐rich arenes with allylic alcohols.
ChemInform Abstract: Copper‐Mediated Chelation‐Assisted ortho‐Nitration of (Hetero)arenes.
Authors: Zhang Lin , Liu Zhenhua , Li Huiqin , Fang Guichun , Barry Badru‐Deen , Belay Tuemay Abadi , Bi Xihe , Liu Qun
Published: March 2012

Optimized conditions A) allow the preparation of various products bearing electron‐donating or electron‐withdrawing groups at the 2‐, 3‐ or 4‐positions of the phenyl ring, where 2‐pyridyl is the most effective directing group.
ChemInform Abstract: A Catalytic Asymmetric Borono Variant of Hosomi—Sakurai Reactions with N,O‐Aminals.
Authors: Huang Yi‐Yong , Chakrabarti Ananya , Morita Naohide , Schneider Uwe , Kobayashi Shu
Published: March 2012

Under mild Lewis acidic conditions, boronates are more reactive and selective than silicon‐based reagents.
ChemInform Abstract: TiCl4‐Promoted Mukaiyama Aldol Reaction of Fluorinated Silyl Enolates for the Construction of a Quaternary Carbon Center.
Authors: Wang Wengui , Chen Qing‐Yun , Guo Yong
Published: March 2012

The Mukaiyama aldol reaction of fluorinated silyl enolate (I) with various aldehydes affords α‐fluoro‐β‐hydroxyphenones with up to 86% d.e.
ChemInform Abstract: Palladium‐Catalyzed Benzylation of Unprotected Anthranilic Acids with Benzyl Alcohols in Water.
Authors: Hikawa Hidemasa , Yokoyama Yuusaku
Published: March 2012

The title process affords dibenzylated acids in good yields.
ChemInform Abstract: Isocyanide‐Based Multicomponent Reactions: Synthesis of Alkyl‐2‐(1‐(alkylcarbamoyl)‐2,2‐dicyanoethyl)benzoate and Isochromeno[3,4‐b]pyrrole Derivatives.
Authors: Soleimani Ebrahim , Zainali Mohsen
Published: March 2012

Base‐catalyzed treatment of 2‐formylbenzoic acids with malononitrile and isocyanides provides a new and efficient approach to isochromenopyrroles like (IV).
ChemInform Abstract: New Preparation of Benzylic Aluminum and Zinc Organometallics by Direct Insertion of Aluminum Powder.
Authors: Bluemke Tobias D. , Groll Klaus , Karaghiosoff Konstantin , Knochel Paul
Published: March 2012

A wide range of benzylic aluminum sesquichlorides is prepared under conditions A).
ChemInform Abstract: Synthesis of Azines in Solid State: Reactivity of Solid Hydrazine with Aldehydes and Ketones.
Authors: Lee Byeongno , Lee Kyu Hyung , Cho Jaeheung , Nam Wonwoo , Hur Nam Hwi
Published: March 2012

The reaction proceeds by solid state grinding of a hydrazine and aldehydes or ketones to afford the conjugated azines with < 97% yield.
ChemInform Abstract: Synthesis of 2‐Naphthols via Carbonylative Stille Coupling Reaction of 2‐Bromobenzyl Bromides with Tributylallylstannane Followed by the Heck Reaction.
Authors: Dai Yao , Feng Xiujuan , Liu Hesong , Jiang Hua , Bao Ming
Published: March 2012

The reaction with vinylstannane also yields 2‐naphthols.
ChemInform Abstract: A New Synthesis of trans‐2,3‐Diaryloxiranes and 2‐(1H‐Benzo[d][1,2,3]triazol‐1‐yl)‐1‐arylethanols via the Reactions of 1‐Benzyl‐3‐methylbenzotriazolium Ylide with Aryl Aldehydes.
Authors: Xiao Xiaohui , Lin Daqin , Tong Shuitian , Mo Hailan
Published: March 2012

Under optimized conditions the reaction of aryl chlorides with benzotriazolium ylide (I) allows the highly selective formation of trans‐2,3‐diaryloxiranes.
ChemInform Abstract: Organocatalytic Asymmetric Neber Reaction for the Synthesis of 2H‐Azirine Carboxylic Esters.
Authors: Sakamoto Shota , Inokuma Tsubasa , Takemoto Yoshiji
Published: March 2012

The reaction of β‐ketoxime sulfonates is catalyzed by a bifunctional thiourea catalyst to afford the enantioenriched target products with good yields and high enantioselectivities.
ChemInform Abstract: Selectivities in the Reaction of Vicinal Diimines and Acyl Chlorides.
Authors: Wang Zhixin , Chen Ning , Xu Jiaxi
Published: March 2012

A variety of mono‐cis‐β‐lactams is obtained in the title reactions.
ChemInform Abstract: Synthesis and Cytotoxic Evaluation of Novel Paraconic Acid Analogues.
Authors: Le Floch Camille , Le Gall Erwan , Leonel Eric , Martens Thierry , Cresteil Thierry
Published: March 2012

A rapid and efficient method for the synthesis of the title compounds (IV) and (VI) is presented.
ChemInform Abstract: Catalytic, Enantioselective Intramolecular Hydroamination of Primary Amines Tethered to Di‐ and Trisubstituted Alkenes.
Authors: Chapurina Yulia , Ibrahim Houssein , Guillot Regis , Kolodziej Emilie , Collin Jacqueline , Trifonov Alexander , Schulz Emmanuelle , Hannedouche Jerome
Published: March 2012

The new complexes generated form Li(thf)4[Y(CH2SiMe3)4] and the diamines (I) effectively promote the asymmetric cyclization of amine substrates.
ChemInform Abstract: Diastereoselective Synthesis of 1,3,5‐Trisubstituted 4‐Nitropyrrolidin‐2‐ones via a Nitro‐Mannich/Lactamization Cascade.
Authors: Pelletier Sophie M.‐C. , Ray Peter C. , Dixon Darren J.
Published: March 2012

A one‐pot reaction of amines, aldehydes and nitropropanoate esters leads to the target compounds with moderate to high diastereoselectivities.
ChemInform Abstract: Synthesis and Biological Evaluation of 2‐Indolinone Derivatives as Potential Antitumor Agents.
Authors: Zou Hongbin , Zhang Liang , Ouyang Jingfeng , Giulianotti Marc A. , Yu Yongping
Published: March 2012

A variety of 3‐substituted indolinones and azaindolinones is synthesized and evaluated for antiproliferative effects.
ChemInform Abstract: InCl3‐Catalyzed Four‐Component Reaction: A Novel Synthesis of N‐Carbazolyl Dihydropyridines.
Authors: Yamuna Ezhumalai , Zeller Matthias , Prasad Karnam Jayarampillai Rajendra
Published: March 2012

The efficient domino process renders possible the synthesis of various pharmaceutically important products in high yields within a short time.
ChemInform Abstract: Application of Silica Gel‐Supported Polyphosphoric Acid (PPA/SiO2) as a Reusable Solid Acid Catalyst to the Synthesis of 3‐Benzoylisoxazoles and Isoxazolines.
Authors: Itoh Ken‐ichi , Aoyama Tadashi , Satoh Hiroaki , Fujii Yuki , Sakamaki Hiroshi , Takido Toshio , Kodomari Mitsuo
Published: March 2012

1,3‐Dipolar cycloaddition of alkynes or alkenes with nitrile oxides results in regioselective formation of the title compounds.
ChemInform Abstract: Formation of Isoxazolidines by Enantioselective Copper‐Catalyzed Annulation of 2‐Nitrosopyridine with Allylstannanes.
Authors: Chatterjee Indranil , Froehlich Roland , Studer Armido
Published: March 2012

A Walphos‐type ligand is found to be highly efficient for the formal [3 + 2] cycloaddition to give isoazolidines (III), in most cases with excellent stereoselectivity.
ChemInform Abstract: Regioselective Synthesis and Slow‐Release Suzuki—Miyaura Cross‐Coupling of MIDA Boronate‐Functionalized Isoxazoles and Triazoles.
Authors: Grob Jonathan E. , Nunez Jill , Dechantsreiter Michael A. , Hamann Lawrence G.
Published: March 2012

Efficient methods to prepare various 5‐arylated isoxazoles and 4‐arylated triazoles are reported.
ChemInform Abstract: One‐Pot Synthesis and Biological Evaluation of 2‐Pyrrolidinyl‐4‐amino‐5‐(3′,4′,5′‐trimethoxybenzoyl)thiazole: A Unique, Highly Active Antimicrotubule Agent.
Authors: Romagnoli Romeo , et al. et al.
Published: March 2012

Novel thiazole derivatives (IV) and (VI) are synthesized in a facile one‐pot procedure.
ChemInform Abstract: Polycyclic N‐Heterocyclic Compounds. Part 67. Reaction of 6,7‐Substituted N‐(Quinazolin‐4‐yl)amidine Derivatives with Hydroxylamine Hydrochloride. Formation of in vitro Inhibitors of Pentosidine.
Authors: Okuda Kensuke , Muroyama Hideki , Hirota Takashi
Published: March 2012

The synthesis of a variety of oxadiazolylphenyl formamide oxime derivatives (V), (VI), (IX) proceeds via reaction of N‐(quinazolin‐4‐yl)amidine derivatives with hydroxylamine hydrochloride.
ChemInform Abstract: Selenium‐Catalyzed Regioselective Cyclization of Unsaturated Carboxylic Acids Using Hypervalent Iodine Oxidants.
Authors: Singh Fateh V. , Wirth Thomas
Published: March 2012

The procedure leads to six‐membered lactones in good yields.
ChemInform Abstract: Organocatalyzed Enantioselective Synthesis of 2‐Amino‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carboxylates.
Authors: Ramireddy Naresh , Abbaraju Santhi , Zhao Cong‐Gui
Published: March 2012

Condensation of cyclic 1,3‐diones with alkylidene cyanoacetates in the presence of the quinine‐based thiourea renders possible the preparation of various biologically interesting benzopyran structures.
ChemInform Abstract: Rhodium(III)‐Catalyzed Synthesis of Pyridines from α,β‐Unsaturated Ketoximes and Internal Alkynes.
Authors: Too Pei Chui , Noji Toshiharu , Lim Ying Jie , Li Xingwei , Chiba Shunsuke
Published: March 2012

Under optimized conditions, the reaction allows the synthesis of highly substituted products.
ChemInform Abstract: Ruthenium‐Catalyzed C—H/N—O Bond Functionalization: Green Isoquinolone Syntheses in Water.
Authors: Ackermann Lutz , Fenner Sabine
Published: March 2012

The target products can be obtained from N‐methoxybenzamide or hydroxamic acids.
ChemInform Abstract: The Synthesis of 2‐Nitroaryl‐1,2,3,4‐tetrahydroisoquinolines, Nitro‐Substituted 5,6‐Dihydrobenzimidazo[2,1‐a]isoquinoline N‐Oxides and Related Heterocycles as Potential Bioreducible Substrates for the Enzymes NAD(P)H: Quinone Oxidoreductase 1 and E. coli Nitroreductase.
Authors: Burke Philip J. , Wong Lai Chun , Jenkins Terence C. , Knox Richard J. , Stanforth Stephen P.
Published: March 2012

A series of title compounds is prepared and evaluated as potential bioreducible substrates for the enzymes NAD(P)H: quinone oxireductase 1 (NQO1) and Escherichia coli nitroreductase (NR).
ChemInform Abstract: Tandem One‐Pot Synthesis of Polysubstituted Pyridines Using the Blaise Reaction Intermediate and 1,3‐Enynes.
Authors: Chun Yu Sung , Lee Jun Hee , Kim Ju Hyun , Ko Young Ok , Lee Sang‐gi
Published: March 2012

Sequential reaction of nitriles, Reformatsky reagents and 1,3‐enynes proceeds with complete regio‐ and chemoselectivity to provide the polysubstituted pyridines.
ChemInform Abstract: Solvent‐Free Sonochemical One‐Pot Three‐Component Synthesis of 2H‐Indazolo[2,1‐b]phthalazine‐1,6,11‐triones and 1H‐Pyrazolo[1,2‐b]phthalazine‐5,10‐diones.
Authors: Shukla Gaurav , Verma Rajiv K. , Verma Girijesh K. , Singh Maya Shankar
Published: March 2012

The reaction under conventional heating or ultrasound gives the title compounds in comparable yields and reaction times.
ChemInform Abstract: New Imidazo[2,1‐b]thiazole Derivatives: Synthesis, in vitro Anticancer Evaluation, and in silico Studies.
Authors: Park Jin‐Hun , El‐Gamal Mohammed I. , Lee Yong Sup , Oh Chang‐Hyun
Published: March 2012

Compounds (IIIb), (IIIf), (IVb), and (IVd)—(IVg) exhibit higher activity against A375P human melanoma cell line than the reference compound sorafenib.
ChemInform Abstract: Design, Synthesis and Biological Study of Novel Pyrido[2,3‐d]pyrimidine as Antiproliferative CDK2 Inhibitors.
Authors: Ibrahim Diaa A. , Ismail Nasser S. M.
Published: March 2012

Design and synthesis of a small library of 4‐aminopyrido[2,3‐d]pyrimidine derivatives are reported.
ChemInform Abstract: Synthesis and in vitro EGFR (ErbB1) Tyrosine Kinase Inhibitory Activity of 4‐N‐Substituted 6‐Aryl‐7H‐pyrrolo[2,3‐d]pyrimidine‐4‐amines.
Authors: Kaspersen Svein Jacob , Soerum Christopher , Willassen Veronica , Fuglseth Erik , Kjoebli Eli , Bjoerkoey Geir , Sundby Eirik , Hoff Baard Helge
Published: March 2012

Title compounds like (VIII) are synthesized and tested for their in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity.
ChemInform Abstract: Facile Syntheses of 7,9‐Dimethoxypyrrolo[3,2,1‐ij]quinolin‐6‐ones.
Authors: Rajput Santosh , Leu Chao‐wei , Wood Kasey , Black David StC , Kumar Naresh
Published: March 2012

Two approaches starting from indoles (I) or quinolinone (VIII) are presented for the synthesis of title compounds (V) and (XI), respectively.
ChemInform Abstract: Phosphorus Pentachloride‐Induced Transformation of (1,2,3‐Thiadiazol‐5‐yl)hydrazones of Acetophenone.
Authors: Kalinina T. A. , Prokhorova P. E. , Glukhareva T. V. , Morzherin Yu. Yu.
Published: March 2012

The transformation of the 1,2,3‐thiadiazole moiety of title compounds (I), induced by phosphorus pentachloride, involves 4 atoms of the side chain and leads to triazolothiadiazine‐3‐carbonyl chlorides (II).
ChemInform Abstract: Polyethylene Glycol (PEG‐400) as an Efficient and Recyclable Reaction Medium for the One‐Pot Synthesis of N‐Substituted Azepines under Catalyst‐Free Conditions.
Authors: Mallepalli Raghu , Yeramanchi Lingappa , Bantu Rajashaker , Nagarapu Lingaiah
Published: March 2012

A facile synthesis of N‐substituted azepine 2,3‐diesters is achieved through three‐component condensation in PEG 400 without the need for any catalyst.
ChemInform Abstract: The N‐Aryl Aminocarbonyl ortho‐Substituent Effect in Cu‐Catalyzed Aryl Amination and Its Application in the Synthesis of 5‐Substituted 11‐Oxo‐dibenzodiazepines.
Authors: Diao Xiaoqiong , Xu Lanting , Zhu Wei , Jiang Yongwen , Wang Haoyang , Guo Yinlong , Ma Dawei
Published: March 2012

A variety of biologically important 11‐oxodibenzodiazepines is prepared tolerating a wide range of functional groups in the amine partner and substitution at both aromatic rings.
ChemInform Abstract: Radical Addition of Silanes to Alkenes Followed by Oxidation.
Authors: Palframan Matthew J. , Parsons Andrew F. , Johnson Paul
Published: March 2012

Phenyldimethylsilane and trichlorosilane add efficiently to terminal alkynes in the presence of triethylborane as radical initiator.
ChemInform Abstract: Radical‐Mediated anti‐Markovnikov Hydrophosphonation of Olefins.
Authors: Daeffler Christopher S. , Grubbs Robert H.
Published: March 2012

The reaction can be performed using radical initiator ACN or under photochemical conditions.
ChemInform Abstract: Synthesis and in vitro Anticancer Activity of 6,7‐Methylenedioxy (or 5‐Hydroxy‐6‐methoxy)‐2‐(substituted selenophenyl)quinolin‐4‐one Analogues.
Authors: Kuo Sheng‐Chu , et al. et al.
Published: March 2012

A modified Camps approach is used for the synthesis of quinoline derivatives (IV).
ChemInform Abstract: Synthesis and Testing of Trifluoromethyl‐Containing Phosphonate—Peptide Conjugates as Inhibitors of Serine Hydrolases.
Authors: Sokolova Nadezhda V. , Nenajdenko Valentine G. , Sokolov Vladimir B. , Serebryakova Olga G. , Makhaeva Galina F.
Published: March 2012

The compounds (II) and (III) are screened for their inhibitory activity towards acetylcholinesterase (AChE), butylcholinesterase (BChE), and carboxylesterase (CaE).
ChemInform Abstract: (R)‐[(2‐Oxo‐4‐thiazolidinyl)methyl]triphenylphosphonium Iodide: A Wittig Reagent for the Synthesis of Cystein‐Derived Alkenes.
Authors: Shaffer Christina J. , Fan RuLin , Lewis Michael D. , Kowalczyk James J.
Published: March 2012

A synthesis of enantiopure cysteine‐derived phosphonium reagent (IV), amenable to the kg scale, is developed and its utilization in Wittig reactions is demonstrated.
ChemInform Abstract: C‐Quaternary Vinylglycinols by Metal‐Catalyzed Cyclization of Allylic Bistrichloroacetimidates.
Authors: Klimovica Kristine , Grigorjeva Liene , Maleckis Ansis , Popelis Juris , Jirgensons Aigars
Published: March 2012

Bistrichloroacetimidates (III) undergo highly regioselective cyclization in the presence of Pd or Lewis acid catalysts to give vinyloxazolines.
ChemInform Abstract: Total Synthesis and Bioactivity of the Marine Alkaloid Pityriacitrin and Some of Its Derivatives.
Authors: Zhang Puyong , Sun Xiaofei , Xu Bin , Bijian Krikor , Wan Shengbiao , Li Guigen , Alaoui‐Jamali Moulay , Jiang Tao
Published: March 2012

A novel access to pityriacitrin (IIIa) and several of its analogues via modified Pictet—Spengler reaction is described.
ChemInform Abstract: One‐Pot Synthesis of 2‐Nitrooxyalkoxylated Inosine Analogues Using Cyclic Ether and Isoamyl Nitrite.
Authors: Sakakibara Norikazu , Komatsu Masahiro , Maruyama Tokumi
Published: March 2012

First examples of 2‐nitrooxyalkoxylated nucleosides are obtained by using cyclic ethers and isoamyl nitride.
ChemInform Abstract: Two New Flavones from Uvaria macrophylla Roxb. var. microcarpa and Their Cytotoxic Activities.
Authors: Chen Zhong , Liu Xue‐Run , Liu Yan‐Li , Xu Qiong‐Ming , Yang Shi‐Lin
Published: March 2012

Macrophyllain A (I) and B (II) are tested against A 549, SK‐MES‐1, and NCI‐446 lung carcinoma cells.
ChemInform Abstract: Adventures in Crystal Growth: Synthesis and Characterization of Single Crystals of Complex Intermetallic Compounds
Authors: Phelan W. Adam , Menard Melissa C. , Kangas Michael J. , McCandless Gregory T. , Drake Brenton L. , Chan Julia Y.
Published: March 2012

Review: 162 refs.
ChemInform Abstract: Collective Phenomena in the LiHoxY1‐xF4 Quantum Ising Magnet: Recent Progress and Open Questions
Authors: Gingras Michel J. P. , Henelius Patrik
Published: March 2012

Review: 83 refs.
ChemInform Abstract: Chemistry and Electronic Structure of Iron‐Based Superconductors
Authors: Sefat Athena S. , Singh David J.
Published: March 2012

Review: 96 refs.
ChemInform Abstract: Gold Catalysis: Effect of Particle Size on Reactivity Towards Various Substrates
Authors: Guczi Laszlo , Beck Andrea , Paszti Zoltan
Published: March 2012

Review: 42 refs.
ChemInform Abstract: Supported Nanoparticles and Selective Catalysis
Authors: Zhang Wangqing , Wang Da , Yan Rui
Published: March 2012

Review: 224 refs.
ChemInform Abstract: Modeling of Heterogeneous‐Catalytic Reactions in Porous Media
Authors: Keil Frerich J.
Published: March 2012

Review: 227 refs.
ChemInform Abstract: Morphology and Pore Control in Carbon Materials via Templating.
Authors: Inagaki M. , Orikasa H. , Morishita T.
Published: March 2012

Review: 246 refs.
ChemInform Abstract: Quinquevalent Phosphorus Acids
Authors: Balczewski Piotr , Skalik Joanna
Published: March 2012

Review: 214 refs.
ChemInform Abstract: Firtz Haber: Flawed Greatness of Person and Country
Authors: Stern Fritz
Published: March 2012

Review: 7 refs.
ChemInform Abstract: Enzymatic Recognition of 2′‐Modified Ribonucleoside 5′‐Triphosphates: Towards the Evolution of Versatile Aptamers
Authors: Lauridsen Lasse H. , Rothnagel Joseph A. , Veedu Rakesh N.
Published: March 2012

Review: 70 refs.
ChemInform Abstract: Miscellaneous Applications of Ferrocene‐Based Peptides/Amides.
Authors: Lal Bhajan , Badshah Amin , Altaf Ataf Ali , Khan Nasir , Ullah Shafiq
Published: March 2012

Review: 87 refs.
ChemInform Abstract: Recent Progress in the Preparation of Organoboron Reagents via Direct Borylations
Authors: Nishida Mayumi , Tagata Tsuyoshi
Published: March 2012

Review: ca. 50 refs.
ChemInform Abstract: Development of New Phosphine Ligands (BRIDPs) for Efficient Palladium‐Catalyzed Coupling Reactions and Their Application to Industrial Processes
Authors: Suzuki Ken , Hori Yoji , Nakayama Yuji , Kobayashi Tohru
Published: March 2012

Review: about 50 refs.
ChemInform Abstract: Usage of the Carboxylate Leaving Group in Transition‐Metal‐Catalyzed Cross‐Coupling and Related Reactions
Authors: Kuwano Ryoichi
Published: March 2012

Review: ca. 80 refs.
ChemInform Abstract: Transition Metal Catalyzed Alkylation at sp3‐, sp2‐, and sp‐Carbons
Authors: Kambe Nobuaki , Terao Jun , Iwasaki Takanori
Published: March 2012

Review: about 60 refs.
ChemInform Abstract: Designing Molecular Catalysts with Enhanced Lewis Acidity
Authors: Mandal Swadhin K. , Roesky Herbert W.
Published: March 2012

Review: ca. 100 refs.
ChemInform Abstract: Modern Strategies in Supramolecular Catalysis
Authors: Ballester Pablo , Vidal‐Ferran Anton , van Leeuwen Piet W. N. M.
Published: March 2012

Review: 143 refs.
ChemInform Abstract: Synthetic Efforts Towards the Synthesis of Fluorinated C‐Glycosidic Analogues of α‐Galactosylceramides
Authors: Leclerc Eric , Pannecoucke Xavier
Published: March 2012

Review: 86 refs.
ChemInform Abstract: Application of Silicon‐Based Methodologies for the Synthesis of Functionalized Mono‐ and Bisphosphonic Acids
Authors: Romanenko Vadim D. , Shevchuk Michael V. , Kukhar Valery P.
Published: March 2012

Review: 213 refs.
ChemInform Abstract: Si—C Coupling Reaction of Hydrosilane with Activated Organic Compounds: A Facile Synthetic Route to Organosilicon Compounds
Authors: Yoo Bok Ryul , Han Joon Soo
Published: March 2012

Review: 95 refs.
ChemInform Abstract: Organocatalytic Enantioselective Methodologies Using Morita—Baylis—Hillman Carbonates and Acetates
Authors: Rios Ramon
Published: March 2012

Review: 40 refs.
ChemInform Abstract: Nature‐Like Synthetic Alkyl Branched Chain Glycolipids: Chemical Structure and Self‐Assembly Properties
Authors: Hashim Rauzah , Sugimura Akihiko , Minamikawa Hiroyuki , Heidelberg Thorsten
Published: March 2012

Review: 103 refs.
ChemInform Abstract: Heterocyclization of Allenes Catalyzed by Late Transition Metals: Mechanisms and Regioselectivity
Authors: Alcaide Benito , Almendros Pedro , del Campo Teresa Martinez , Soriano Elena , Marco‐Contelles Jose
Published: March 2012

Review: 87 refs.
ChemInform Abstract: Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6‐O‐Benzylidene‐Protected Mannopuranosyl Donors and Related Species
Authors: Aubry Sylvain , Sasaki Kaname , Sharma Indrajeet , Crich David
Published: March 2012

Review: 151 refs.
ChemInform Abstract: The Pyrolytic Behavior of Cellulose in Lignocellulosic Biomass: A Review
Authors: Shen Dekui , Xiao Rui , Gu Sai , Luo Kaihong
Published: March 2012

Review: 115 refs.
ChemInform Abstract: Capsules and Cavitands: Synthetic Catalysts of Nanometric Dimension, Supermolecular Catalysis
Authors: Borsato Giuseppe , Rebek Julius Jr. , Scarso Alessandro
Published: March 2012

Review: 132 refs.
ChemInform Abstract: Progress in the Chemistry of Second Generation Hypericin‐Based Photosensitizers
Authors: Waser Mario , Falk Heinz
Published: March 2012

Review: 110 refs.
ChemInform Abstract: Imidazolium‐Based Liquid Crystals: A Modular Platform for Versatile New Materials with Finely Tuneable Properties and Behavior
Authors: Douce Laurent , Suisse Jean‐Moise , Guillon Daniel , Taubert Andreas
Published: March 2012

Review: 56 refs.
ChemInform Abstract: Substituent Effects on Non‐Covalent Interactions with Aromatic Rings: Insights from Computational Chemistry
Authors: Raju Rajesh K. , Bloom Jacob W. G. , An Yi , Wheeler Steven E.
Published: March 2012

Review: 212 refs.
Synthesis and Characterization of Dendrimer‐Encapsulated Bimetallic Core‐Shell PdPt Nanoparticles
Authors: Li Guoping , Lu Wenting , Luo Yunjun , Xia Min , Chai Chunpeng , Wang Xiaoqing
Published: March 2012

Using a successive method, PAMAM dendrimer‐encapsulated bimetallic PdPt nanoparticles have been successfully prepared with core‐shell structures (Pd@Pt DENs). Evidenced by UV‐vis spectra, high resolution transmission electron microscopy, and X‐ray energy dispersive spectroscopy (EDS), the obtained Pd@Pt DENs are monodispersed and located inside the cavity of dendrimers, and they show a different structure from monometallic Pt or Pd and alloy PdPt DENs. The core‐shell structure of Pd@Pt DENs is further confirmed by infrared measurements with carbon monoxide (IR‐CO) probe. In order to prepare Pd@Pt DENs, a required Pd/Pt ratio of 1:2 is determined for the Pt shell to cover the Pd core completely. Finally, a mechanism for the formation of Pd@Pt DENs is proposed.
Synthesis, Spectral, Thermal and Biological Studies of Mn(II), Co(II), Ni(II) and Cu(II) Complexes with 1‐(((5‐Mercapto‐1H‐1,2,4‐triazol‐3‐yl)imino)‐methyl)naphthalene‐2‐ol
Authors: Issa Raafat Mostafa , Gaber Mohammed , Al‐Wakiel Nadia Abd‐Elhamed , Fathalla Shaimaa Kamal
Published: March 2012

Mn(II), Co(II), Ni(II) and Cu(II) complexes of 5‐mercapto‐1,2,4‐triazol‐3‐imine‐2′‐hydroxynaphthaline have been synthesized and characterized by elemental analysis, IR, 1H NMR, EI‐mass, UV‐Vis, and ESR (electron spin resonance) spectra, molar conductance, magnetic moment measurements, DC conductivity and thermogravimetric analysis. IR spectra confirm that the ligand molecule existed in both thione and thiole forms. The molar conductance values indicate the complexes are nonelectrolyte. The magnetic moment values of the complexes display paramagnetic behavior. All studies confirm the formation of an octahedral geometry for complex 1 and the other complexes have tetrahedral geometrical structures. The structures of the complexes have also been theoretically studied by using the molecular mechanic calculations by the hyperchem. 8.03 molecular modeling program which confirm the proposed structures. The Schiff‐base ligand and its metal complexes have also been screened for their antimicrobial activities.
Enhanced Electrochemical Capacitive Properties of Nickel‐Cobalt Oxide Nano‐flakes Materials
Authors: Kong Lingbin , Deng Li , Lang Junwei , Ji Xu , Luo Yongchun , Kang Long
Published: March 2012

Nickel‐cobalt oxide nano‐flakes materials are successfully synthesized by a facile chemical co‐precipitation method followed by a simple calcination process. The studies show that the as‐prepared nickel‐cobalt oxides with different Ni/Co ratio are composed of NiO and Co3O4 compounds. The Co0.56Ni0.44 oxide material, which exhibits a mesoporous structure with a narrow distribution of pore size from 2 to 7 nm, possesses markedly enhanced charge‐discharge properties at high current density compared with the pure NiO and pure Co3O4. The Co0.56Ni0.44 oxide electrode shows a specific capacitance value of 1227 F/g at 5 mA/cm2, which is nearly three times greater than that of the pure NiO electrode at the same current density.
Synthesis of Some New 1,4‐Dihydropyridine Derivatives through a Facile One‐pot Hantzsch Condensation Catalyzed by Triethylamine
Authors: Ghalem Wassima , Boulcina Raouf , Debache Abdelmadjid
Published: March 2012

A facile and efficient synthesis of new 1,4‐dihydropyridine derivatives was reported via Hantzsch three‐component condensation reaction of aldehydes or formylphenylboronic acids, ethyl acetoacetate, and ammonium acetate in the presence of a catalytic amount of triethylamine under solvent‐free conditions. The method described here offers several advantages including high yields, short reaction times, and simple work‐up procedure.
A Supermolecule Assembled by Sodium Cation, Crown Ether and α‐Dawson Heteropolyanion
Authors: Zhu Linli , Lu Xiaoming
Published: March 2012

The supermolecular based on sodium molybdate(VI) and sulfate, dibenzo‐18‐crown‐6 was synthesized in acetonitrile and characterized by elemental analysis, IR, 1H NMR, single crystal X‐ray diffraction, indicating that it contains [S2Mo18O62]4+ and [Na(DB18C6)(H2O)]+, where each sodium ion is deviated from the plane defined by the oxygen atoms in the corresponding crown ether. The compound crystallizes in the monoclinic space group C2/c with a=3.29332(10) nm, b=1.90917(6) nm, c=2.63132(7) nm, β=121.6630(10)°, V=14081.8(7) nm3, Z=8, T=293(2) K, and R1 (wR2)=0.0177 (0.1525). The compound exhibits a novel organic‐inorganic structure, in which the crown ether‐sodium complexes are coordinated to the terminal oxygen atoms of Mo18O54 and the oxygen atoms of water molecule.
Syntheses, Structures, and Properties of Two Coordination Compounds of Pb(II) and Cd(II) with Quinoline‐8‐oxy‐acetate Acid
Authors: Liang Jiehui , Wei Qing , Qiao Chengfang , Xia Zhengqiang , Ye Gang , Chen Sanping
Published: March 2012

Quinoline‐8‐oxy‐acetate acid (8‐qoacH) reacts with M(II) (M=Pb and Cd) to give rise to two coordination complexes [Pb(8‐qoac)2] (1) and [Cd(8‐qoac)(bdc)0.5(H2O)2] (2) under hydrothermal conditions. They are characterized by single‐crystal X‐ray diffraction, IR, elemental, thermal analyses and luminescent analysis. The Pb metal centers connect the 8‐qoac anions to form a 1D linear chain in 1. In 2, two symmetrical [Cd(8‐qoac)(H2O)2] are bridged by a 1,4‐bdc2− to generate a coordination unit [Cd(8‐qoac)(bdc)0.5(H2O)2], and all the units are further connected to a 2D supramolecular layer‐like structure via hydrogen bonds. TG analyses indicate that 1 exhibits higher thermostability than 2. Fluorescence spectrum of compound 2 in solid state shows strong fluorescence property.
Promotion on Nucleation and Aggregation of Calcium Oxalate Crystals by Injured African Green Monkey Renal Epithelial Cells
Authors: Zhang Shen , Peng Hua , Yao Xiuqiong , Su Zexuan , Ouyang Jianming
Published: March 2012

The purpose of this work was to detect the properties of African green monkey renal epithelial cells (Vero) after oxidative injury and to study the mediation of the injured Vero on aggregation and formation of calcium oxalate crystals. This injury model was induced by 0.15 mmol/L H2O2 according to the pretest evaluation. The results suggested that H2O2 could injure Vero significantly and decrease cell viability in a time‐dependent manner for exposure time of 0.5–2 h. After cell injury, the indexes connected with oxidative injury changed. The malondialdehyde (MDA) content and osteopontin (OPN) expression increased, while superoxide dismutase (SOD) level decreased. It resulted in the increase of both the amount of CaOxa crystals and the degree of crystal aggregation on the injured cells. This work indicated that injured cells promoted the formation of calcium oxalate monohydrate (COM) crystals, thus increased the risk of formation of urinary stone.
Optimized Palladium(0)‐catalyzed Suzuki Cross‐coupling Reaction of Polystyrene‐supported Selenenyl Flavanones: A Convenient Preparation of Biaryl‐chromen‐4‐one
Authors: Tang E , Li Wen , Gao Zhangyong , Zhang Lianpeng , Ma Qiushi
Published: March 2012

Application of the Suzuki cross‐coupling reaction for efficient synthesis of diverse substituted biaryl‐chromen‐4‐ones using an optimized palladium(0) catalyst system is reported. The coupling of arylboronic acids with the resin‐bound bromoflavanones which were prepared by organoselenium‐induced regioselective intramolecular cyclization of bromo‐2‐hydroxylchalcones proceeded smoothly. Biaryl‐chromen‐4‐ones were synthesized by subsequent selenoxide syn‐elimination in good total yields.
Eine „bärchenstarke“ Reduktion
Authors: Herriger Cornelia , Schmitz Wolfgang , Zajonc Stefan , Ducci Matthias
Published: March 2012

Ausgehend von faszinierenden Experimenten mit Gummibärchen wird im vorliegenden Beitrag ein Konzept vorgestellt, mit dem der Themenkreis „Reduktion von Azofarbstoffen“ anhand zahlreicher Experimente von Schülerinnen und Schülern im Rahmen eines angeleiteten forschenden Unterrichts erschlossen werden kann.
Frischer Wind beim Experimentieren
Authors: Hadenfeldt Jan Christoph , Neumann Knut
Published: March 2012

Experimentierkästen sollen Schülerinnen und Schülern die Möglichkeit bieten, ohne fachkundige Aufsicht naturwissenschaftliche Fragestellungen zu bearbeiten. Die beiliegenden Experimentieranleitungen sollen sie dabei begleiten – im Idealfall ohne rezeptartig durch die Experimente zu leiten. Im Rahmen des im vorliegenden Beitrag vorgestellten Projekts haben Schülerinnen und Schüler der Oberstufe handelsübliche Experimentierkästen und Experimentieranleitungen daraufhin untersucht, inwieweit dieser Spagat gelingt.
Total Synthesis of Isoprostanes Derived from Adrenic Acid and EPA
Authors: Oger Camille , Bultel‐Poncé Valérie , Guy Alexandre , Durand Thierry , Galano Jean‐Marie
Published: March 2012

Enantiomerically enriched F2‐dihomo‐isoprostanes and F3‐isoprostanes have been synthesized. Such compounds are derived from the action of reactive oxygen species on the phospholipid‐bound polyunsaturated fatty acids (PUFA), adrenic acid and eicosapentaenoic acid, respectively. Of special interest are the F2‐dihomo‐isoprostanes because they could represent potential biomarkers for myelin damage as its main PUFA constituent is adrenic acid. Our strategy, based on a pivotal enantiomerically enriched intermediate, has allowed access to F2‐dihomo‐IsoP and both C5 epimers of 5‐F3t‐IsoP for the first time.
Determination of Blasticidin S in Spiked Rice Using SW Voltammetry with a Renewable Silver Amalgam Film Electrode
Authors: Skrzypek Slawomira , Smarzewska Sylwia , Ciesielski Witold
Published: March 2012

Blasticidin S (BS) was determined in spiked rice samples by square wave voltammetry (SWV) and square wave stripping voltammetry (SWSV) using a cyclic renewable silver amalgam film electrode (Hg(Ag)FE). It was found that the compound can act as an electrocatalyst. In BrittonRobinson buffer at pH 7.0 a signal connected with the hydrogen evolution reaction was detected at −1.2 V versus Ag/AgCl. Validation of the method was carried out. The detection and quantification limits were found to be 2.13×10−8 mol L−1; 7.10×10−8 mol L−1 for SWV and 2.65×10−9 mol L−1; 8.85×10−9 mol L−1 for SWSV, respectively.
Oxidation of DNA Bases Influenced by the Presence of Other Bases
Authors: Shuhua Goh Madeline , Pumera Martin
Published: March 2012

Electrochemical detection of DNA is a highly important topic. Here we show that the electrochemical responses of one DNA base (guanine, adenine, cytosine or thymine), in terms of oxidation potential, current intensity, peak width and resolution can be highly influenced by the presence of other DNA bases at electrochemically reduced graphene oxide (ER‐GO) as well as standard glassy carbon electrode. We have observed that the effects were more significant for adenine base on ER‐GO and cytosine base on glassy carbon (GC) electrode. Differences in responses were generally low in a mixture of four different DNA bases but interestingly, deviations become significantly larger when only one or two other bases were present. Our findings are of paramount importance for future developments in DNA detection and analysis since individual DNA bases are not present in isolation in nature or in typical biosensing systems.