bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review of Caregiver Coping Strategies in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Authors: Caga Jashelle , Kiernan Matthew C. , Piguet Olivier
Published: December 2021

Caregivers of patients diagnosed with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) often experience distressing symptoms related to their caregiving role. This review evaluates the existing literature on coping and their relationship to ALS and FTD caregiver psychological wellbeing. Published articles were identified via a systematic search of four databases (Cinahl Complete, Medline, Embase and PsycINFO). Overall, problem-focused coping strategies such as active coping and planning was used most often by ALS and FTD caregivers. Positive emotion-focused coping strategies such as acceptance were also frequently used by FTD caregivers. In contrast, dysfunctional coping strategies such as self-oriented reactions including self-blame, denial and self-preoccupation appeared to be the most salient coping strategy negatively impacting on caregiver psychological wellbeing. Six different coping measures were used and their psychometric properties were typically under-reported or satisfactory at best when reported. While coping is as an important aspect of caregivers’ experience, it remains unclear how the temporal dimensions of the coping process as well as stressor specificity influences psychological adaptation, and consequently, development of targeted caregiver intervention. The need for future studies to define the coping process more clearly in order to capture the unique stressors encountered by ALS and FTD caregivers throughout the different disease stages is emphasised.
Metaphorically Speaking: Living the Art of Nursing and Meaningful Insights
Authors: Carroll Karen
Published: December 2021

The importance of honoring and attending to human expressions, including metaphor, is more than an exercise in rhetorical flourish. Attending to metaphorical expressions is an inherent whole-in-motion connection of living the art of humanbecoming with the attention to honoring personal values and choices. The humanbecoming paradigm offers a person-centered approach and thus advances the trust of persons within the various communities receiving healthcare.
Best Available Evidence or Truth for the Moment: Bias in Research
Authors: Florczak Kristine L.
Published: December 2021

The subject of this column is the nature of bias in both quantitative and qualitative research. To that end, bias will be defined and then both the processes by which it enters into research will be entertained along with discussions on how to ameliorate this problem.
Feeling Listened To: A Parsesciencing Inquiry
Authors: Duarte-Quilao Teodora
Published: December 2021

Feeling listened to as a universal humanuniverse living experience was investigated with the Parsesciencing mode of inquiry. Historians were 10 English-speaking adults between 18 and 65 years old who had been hospitalized, willing to share their experiences of feeling listened to. The inquiry stance was “What is the discerning extant moment of the universal humanuniverse living experience of feeling listened to?” The major discovery of this investigation revealed the discerning extant moment as: Feeling listened to is uplifting recognition amid disconcerting rebuff, as treasured affiliations surfaces with joyful gratification.
A Foundation for the Future: Sowing the Seeds of Illimitable Possibilities in the Rock Garden of Nurse Education
Authors: Yancey Nan Russell
Published: December 2021

In this column, the author shares insights on teaching-learning uncovered in considering the experiences of growing up on a farm, illuminated by insights from a treasured childhood book as perceived through the nursing theoretical lens of humanbecoming. Suggestions for planning and planting for the future of nursing are offered and questions are asked as a guide for the nurse teacher.
Enhancing graduates’ employability through polytechnic–industry collaboration
Authors: Otache Innocent
Published: December 2021

The unemployability of many Nigerian graduates is somewhat attributable to the existing wide collaboration gap between Nigerian higher education institutions and industry. Against this backdrop, this study explores how Nigerian polytechnics and industry can collaborate to enhance graduates’ employability. Adopting a focus group discussion approach, three focus groups involving 20 people (eight polytechnic lecturers, six National Board for Technical Education officials and six industry executives) participated in the study. Content analysis of the focus group discussions revealed the need to involve industry experts in curriculum development and review to meet today’s job requirements in industry. The need to involve industry experts in teaching certain aspects of the curriculum was also highlighted. The findings further revealed the desirability of exposing students and lecturers to industrial work situations to equip them with workplace skills and experience. Additionally, the study found that a comprehensive collaboration policy framework, funding, commitment, mutual benefits and trust are required to achieve successful polytechnic–industry collaboration. This research demonstrates that effective collaboration between polytechnics and industry will help to improve the employability of graduates. The findings provide policy and practical implications for polytechnics, regulatory bodies, industry and government.
Copy the In-group: Group Membership Trumps Perceived Reliability, Warmth, and Competence in a Social-Learning Task
Authors: Montrey Marcel , Shultz Thomas R.
Published: December 2021

Surprisingly little is known about how social groups influence social learning. Although several studies have shown that people prefer to copy in-group members, these studies have failed to resolve whether group membership genuinely affects who is copied or whether group membership merely correlates with other known factors, such as similarity and familiarity. Using the minimal-group paradigm, we disentangled these effects in an online social-learning game. In a sample of 540 adults, we found a robust in-group-copying bias that (a) was bolstered by a preference for observing in-group members; (b) overrode perceived reliability, warmth, and competence; (c) grew stronger when social information was scarce; and (d) even caused cultural divergence between intermixed groups. These results suggest that people genuinely employ a copy-the-in-group social-learning strategy, which could help explain how inefficient behaviors spread through social learning and how humans maintain the cultural diversity needed for cumulative cultural evolution.
Blade shape optimization and internal-flow characteristics of the backward non-volute centrifugal fan
Authors: Zhang Hongjie , Wang Zhengdao , Yang Hui , Zhu Zuchao , Wei Yikun
Published: December 2021

The work proposed the double parameter optimization method of the non-volute centrifugal fan’s blade profile based on the steepest descent method. Total-pressure efficiency improvement at the high-flow area was taken as an optimization objective. A method of applying the steepest descent method to modify the blade profile of backward centrifugal fan is proposed in this paper. The gradient descent direction was analyzed to design the blade profile and obtain the optimal blade profile at a high-flow rate. Besides, numerical simulations were carried out to analyze the aerodynamic performance and the internal flow characteristics of the centrifugal fan by the computational fluid dynamics method. Numerical results showed that the blade profile along the gradient descent was optimized to effectively increase the total pressure and the total pressure efficiency of the original model at the high-flow rate. The steepest descent method for local optimization could improve the fan blade design.
Evaluation of the Clinical Efficacy of Stem Cell Transplantation in the Treatment of Spinal Cord Injury: A Systematic Review and Meta-analysis
Authors: Tang Qiao-Rui , Xue Hui , Zhang Qiao , Guo Ying , Xu Hao , Liu Ying , Liu Jia-Mei
Published: December 2021

Stem cell transplantation has been applied to treat spinal cord injury (SCI) in clinical trials for many years. However, the clinical efficacies of stem cell transplantation in SCI have been quite diverse. The purpose of our study was to systematically investigate the efficacy of stem cell transplantation in patients with SCI. The PubMed, Web of Science, Ovid-Medline, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang, and SinoMed databases were searched until October 27, 2020. Quantitative and qualitative data were analyzed by Review Manager 5.3 and R. Nine studies ( n = 328) were included, and the overall risk of bias was moderate. The ASIA Impairment Scale (AIS) grading improvement rate was analyzed in favor of stem cell transplantation group [odds ratio (OR) = 6.06, 95% confidence interval (CI): 3.16–11.62, P < 0.00001]. Urodynamic indices also showed improvement in bladder function. In subgroup analyses, the results indicated that in patients with complete (AIS A) SCI, with the application of cell numbers between n*(107–108), two cell types (i.e., bone marrow–derived mesenchymal stem cells and bone marrow mononuclears), and treatment time of more than 6 months, stem cell transplantation was more beneficial for sensorimotor function ( P < 0.05 for all groups). The risk of fever incidence in the stem cell transplantation group was 4.22 (95% CI: 1.7–10.22, P = 0.001), and principal component analysis (PCA) suggested it was more related to transplanted cell numbers. Thus, stem cell transplantation can promote functional recovery in SCI patients. Moreover, the type and quantity of transplanted stem cells and treatment time are important factors affecting the therapeutic effect of stem cell transplantation in SCI. Further studies are needed to evaluate the effects and elucidate the mechanisms of these factors on stem cell therapy in SCI.
Progressive turnover-based tax systems and EU state aid law: Case C-562/19 P Commission v. Poland and Case C-596/19 P Commission v. Hungary
Authors: Bouzoraa Yasmine L. , Lindeboom Justin
Published: December 2021

In Commission v. Poland (C-562/19) and Commission v. Hungary (C-596/19) the Court of Justice of the European Union ruled that progressive tax systems based on turnover do not by definition provide selective advantages to undertakings with lower turnovers in violation of EU state aid law. The European Commission had declared a Polish tax on retailers and a Hungarian tax on advertisement incompatible with Article 107(1) TFEU because the progressive, turnover-based taxes favoured undertakings with smaller turnovers over those with larger turnovers. The General Court annulled both Commission decisions because such advantages were inherent to the content and objectives of the general tax system, which was for Poland and Hungary to define. The Court of Justice dismissed the appeals by the Commission, affirming that Member States are free, in line with their fiscal autonomy, to opt for a progressive and/or turnover-based tax system. While turnover-based corporate taxation may have market-distortive effects, the Court was right to dismiss the Commission's appeals. The principles of fiscal autonomy and legal certainty require an assessment of selectivity in light of Member States’ own definition of the content and objectives of their tax systems.
Correlation Between the Fracture Line Plane and Perioperative Deep Vein Thrombosis in Patients with Tibial Fracture
Authors: Cai Xiao , Wang Zhan , Wang Xiao-long , Xue Han-zhong , Li Zi-jun , Jiang Wu-qiang , Nian Yue-wen , Zhu Yang-jun , Zhang Kun , Huang Wei
Published: December 2021

Objective

To explore the correlation between the fracture line inferior plane and perioperative deep venous thrombosis (DVT) in patients with tibial fractures.

Methods

Data was collected from the medical records of 536 consecutive patients with tibial fractures at Xi’an Honghui Hospital. The patients were divided into distal, shaft, and proximal segment groups according to the fracture line inferior plane on radiographs. Multivariate logistic regression models were used to identify the role of the inferior plane of the fracture line in perioperative DVT.

Results

A total of 431 patients were included in the study and 226 patients had perioperative DVT in the lower extremities, including 11 proximal and 215 distal DVTs. Univariate regression analysis showed a significant correlation between the proximal segment and perioperative DVT; however, no correlation was found in the shaft segment group. Additionally, age, coronary heart disease, associated injuries, and time to operation ≥6 days were risk factors for perioperative DVT. However, fixation with intramedullary nails may be a protective factor for perioperative DVT compared with plates. After adjusting for potential confounding factors, the proximal segment group had an increased incidence of perioperative DVT compared to the distal segment group.

Conclusions

The proximal segment may be correlated with an increased incidence of perioperative DVT by 7.30-fold in patients with tibial fractures compared to that in the distal segment. In clinical practice, surgeons should be vigilant for DVT formation in these patients.
Physical, morphological and storage stability of clove oil nanoemulsion based delivery system
Authors: Singh Prastuty , Kaur Gurkirat , Singh Arashdeep
Published: December 2021

Clove oil based Nanoemulsions (NE) were prepared ultrasonically using Tween 80 and soy lecithin as synthetic and natural surfactants, respectively. The developed NEs were characterized for various parameters (particle size, polydispersity index, zeta potential, morphology, viscosity, colour, turbidity and pH) and the comparative effect of both the surfactants at variable levels (oil:tween 80-1:1, 1:2, 1:3 and 1:4 and oil: soy lecithin- 1:1, 1:1.5 and 1:2) was assessed. It was found that the type of surfactant and oil to surfactant ratio significantly affected particle size and stability of NEs. The NE prepared using tween 80 @1:3 had smallest average droplet diameter (40.9 nm). The formulated NEs were stored at 25 °C and 4 °C and analyzed for turbidity, pH and phase separation up to 90 days. Results revealed that the type and concentration of the surfactant significantly influenced the particle size and stability of NEs. NEs prepared using tween 80 were found to be more viscous than those prepared with soy lecithin. The prepared clove oil NEs have important implication to be used as a natural delivery system to increase the shelf life of food products.
Hospital-Based Modified Cogmed Working Memory Training for Youth With ADHD
Authors: (Sol) Sandberg Salek , McAuley Tara
Published: December 2021

Objective:

This study evaluated a modified working memory training program, Cogmed, for ADHD youth.

Method:

Forty youth were randomized to modified Cogmed training (MCT) or treatment as usual (CON). MCT was delivered in an outpatient mental health clinic in 3 weekly 35-minute sessions with a dedicated coach for 10 weeks. Participants completed assessments at baseline, after the intervention, and again 3 months later.

Results:

After controlling for baseline, groups were comparable on working memory, academics, and ADHD symptoms. The MCT group was rated by parents and teachers as having fewer executive function challenges and youth endorsed better self-concept compared with the CON group.

Conclusions:

MCT was associated with some improvement, which could not be attributed to increased working memory capacity and may reflect other facets of the program. Results question the usefulness of Cogmed but highlight considerations for optimizing adherence, engagement, and the therapeutic alliance in interventions for ADHD youth.
Potential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Corona Virus 2 Infection/COVID 19 Through RNA Sequencing and Bioinformatics Analysis
Authors: Prashanth G , Vastrad Basavaraj , Vastrad Chanabasayya , Kotrashetti Shivakumar
Published: December 2021

Introduction:

Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infections (COVID 19) is a progressive viral infection that has been investigated extensively. However, genetic features and molecular pathogenesis underlying remdesivir treatment for SARS-CoV-2 infection remain unclear. Here, we used bioinformatics to investigate the candidate genes associated in the molecular pathogenesis of remdesivir-treated SARS-CoV-2-infected patients.

Methods:

Expression profiling by high-throughput sequencing dataset (GSE149273) was downloaded from the Gene Expression Omnibus, and the differentially expressed genes (DEGs) in remdesivir-treated SARS-CoV-2 infection samples and nontreated SARS-CoV-2 infection samples with an adjusted P value of <.05 and a |log fold change| > 1.3 were first identified by limma in R software package. Next, pathway and gene ontology (GO) enrichment analysis of these DEGs was performed. Then, the hub genes were identified by the NetworkAnalyzer plugin and the other bioinformatics approaches including protein-protein interaction network analysis, module analysis, target gene—miRNA regulatory network, and target gene—TF regulatory network. Finally, a receiver-operating characteristic analysis was performed for diagnostic values associated with hub genes.

Results:

A total of 909 DEGs were identified, including 453 upregulated genes and 457 downregulated genes. As for the pathway and GO enrichment analysis, the upregulated genes were mainly linked with influenza A and defense response, whereas downregulated genes were mainly linked with drug metabolism—cytochrome P450 and reproductive process. In addition, 10 hub genes (VCAM1, IKBKE, STAT1, IL7R, ISG15, E2F1, ZBTB16, TFAP4, ATP6V1B1, and APBB1) were identified. Receiver-operating characteristic analysis showed that hub genes (CIITA, HSPA6, MYD88, SOCS3, TNFRSF10A, ADH1A, CACNA2D2, DUSP9, FMO5, and PDE1A) had good diagnostic values.

Conclusion:

This study provided insights into the molecular mechanism of remdesivir-treated SARS-CoV-2 infection that might be useful in further investigations.
Occupational Related Upper and Low Back Pain Among the Working Population of Ethiopia: Systematic Review and Meta-Analysis
Authors: Mengistu Dechasa Adare , Mulugeta Demmu Yohannes , Alemu Addisu
Published: December 2021

Background:

Back pain, such as upper and low back pain are among the most common musculoskeletal conditions that can cause major public health and socioeconomic problems. Back pain is one of the leading causes of disability that reduces worker performance and well-being and increases absence from work, which can cause an enormous economic burden. In developing countries, particularly in Ethiopia, there is no adequate evidence on the overall prevalence of occupational-related upper and low back pain, and they remain less prioritized and empirically unrepresented. Therefore, this study aimed to determine the prevalence of occupational-related upper and low back pain among the working population of Ethiopia.

Methods:

This systematic review and meta-analysis considered studies conducted in Ethiopia, written in English, and published from 2017 to 2020. Articles were searched from 9 electronic databases (Web of Science, SCOPUS, PubMed, Google Scholar, CINAHL, Cochrane Library, African Index Medicus, African Journals Online database, and Science Direct) using a combination of Boolean logic operators, Medical Subject Headings, and main keywords. The quality assessment of the articles was performed using the Joanna Briggs Institute Critical Appraisal tools to determine the relevance of the articles to the study. A random effects model was used to estimate the pooled prevalence, the 95% confidence interval, and the degree of heterogeneity among the included studies. Sensitivity analyses were performed to identify the influence of outliers and to identify sources of heterogeneity.

Results:

Of the 1114 studies identified from the included databases, 20 studies were included in the systematic review and meta-analysis. The pooled prevalence of occupational-related upper and low back pain in the previous year was (27.1% [95% CI: 18.4, 37.9]) and (54.2% [95% CI: 48.2, 60.0]), respectively. Based on a subgroup analysis by publication year, study population, and regions where the studies were conducted, the prevalence of upper back pain was (43.8% [95% CI: 39.3, 47.7]), (34.7% [95% CI: 33.1, 36.2]), and (36.2% [95% CI: 33.6, 39.0]), respectively, while the prevalence of low back pain was (61.8% [95% CI: 58.9, 64.6], (52.8% [95% CI: 51.3, 54.3]), and (55.2% [95% CI: 51.4, 59.0]), respectively.

Conclusions:

This systematic review and meta-analysis found that 54.2% of the included study participants experienced low back pain in the previous year, while 27.1% experienced upper back pain. The highest prevalence was reported among pedestrian back-loading women.
Evaluating the impact of culturally specific patient-centric behavioral intervention package versus usual care for tobacco cessation among patients attending noncommunicable disease clinics in North India: A single-blind trial pilot study protocol
Authors: Bhatt Garima , Goel Sonu , Gupta Rakesh , Grover Sandeep , Medhi Bikash
Published: December 2021

Background

In a low and middle-income country (LMIC) like India, non—communicable diseases (NCDs) contribute a major proportion (61.8%) of all causes of death. Out of this, 48% of cardiovascular diseases , 23% of Chronic Respiratory Diseases , and 10% of Cancer deaths are attributable to tobacco use. Tobacco use is a major risk factor for NCDs and thus, the tobacco cessation approach is a high priority intervention to combat complications and death among NCD patients. While several interventions are available for tobacco cessation, in resource constraint countries like India, the effectiveness of low-cost, culturally specific patient-centric tobacco cessation behavioral intervention holds a potential that needs to be evaluated. A newly developed evidence-based tobacco cessation intervention package will be compared with the existing/usual care provided under the National Programme for Prevention and Control of Cancers, Diabetes, Cardiovascular Diseases, and Stroke (NPCDCS) at NCD clinics.

Methods and design

2 arm, parallel-group randomized controlled trial.

Participants

Patients aged ≥30 years suffering from NCD, currently using tobacco, and attending NCD clinics in 2 districts of Punjab, India.

Sample size

A total of 200 participants meeting the selection criteria will be recruited. They will be allocated either to the intervention arm or control (usual care) arm (100 each) using block randomization.

Intervention

For the participants, there will be 4 face-to-face disease-specific cessation counseling sessions, disease-specific pamphlets, short text messages in vernacular language, that is, Punjabi. Follow-ups will be done at the third, sixth, ninth, and 12th months.

Primary outcome

Seven-day abstinence, biochemically verified by plasma cotinine levels.

Secondary outcome

Quit attempts, number of sticks/number of times of smokeless tobacco usage in a day, and stage of behavior change in tobacco users.

Discussion

This multicomponent culturally specific-patient-centric behavioral intervention package for tobacco cessation at NCD clinic settings focusing on the individual, family, and social environment could increase the outreach of cessation services using existing resources, thereby strengthening health systems and enhancing the quality of life of NCD patients.

Trial registration

The protocol for the study has been registered with the Clinical Trials Registry in India under the registration number CTRI/2018/01/011643.
The impact of environmental management on firm performance in the U.S. lodging REITs: The moderating role of outside board of directors
Authors: Yeon Jihwan , Lee Seoki , Jolly Phillip M , Mattila Anna S
Published: December 2021

Recently, many firms that have caused direct pollution to the environment have begun to think about the necessity of environmental management. As buildings have played an important role in environmental issues, the real estate industry can no longer ignore demands for environmental management. Research on environmental management has mainly focused on its financial implications. However, there has been no consensus in the literature about the relationship between environmental management and firm performance. By comparing portfolios of environmentally certified properties of 19 lodging Real Estate Investment Trusts, this study explores the relationship between environmental management and firm performance, while taking into account the moderating role of outside board of directors. The relationship between environmental management and firm performance appeared to have mixed results, but this study found a positive moderating effect of outside board of directors. This study provides new insights into the hospitality and the real estate literature from a corporate governance perspective.
The importance of the calculation of angle factors to determine the mean radiant temperature in temperate climate zone: A university office building case
Authors: Özbey Mehmet Furkan , Turhan Cihan
Published: December 2021

Thermal comfort depends on four environmental (air velocity, relative humidity, air temperature, mean radiant temperature) and two personal (clothing insulation and metabolic rate) parameters. Among all parameters, the mean radiant temperature (tr) is the most problematic variable in thermal comfort studies due to its complexity. Measurement methods, calculation methods and assumptions are mostly used to obtain the tr. Researchers mainly prefer to obtain the tr via measurement methods or assumptions due to their easiness compared to the calculation methods. Besides, some researchers use constant values of angle factors in calculation methods. However, using constant values is not proper for every indoor environment, and it causes wrong estimations in the tr and thus the thermal comfort. This paper gives the importance of calculation of angle factors, with an example of a university office building in temperate climate zone, according to the ISO 7726. The angle factors of the room were calculated for a seated occupant from the centre of gravity in three different locations and compared with the constant angle factors. The results indicate that a significant difference (MAPE of 1.02) was found in the tr values, which were obtained by calculation of constant values of angle factors.
Perpetrator witnessing: Testing the norms and forms of witnessing through livestreaming terror attacks
Authors: Mortensen Mette
Published: December 2021

This article studies perpetrator livestreams as an emerging witnessing genre in today’s digital media circuit. Perpetrator livestreams challenge the norms of witnessing by undermining the ethos traditionally associated with testimonies. They also challenge the forms of witnessing by being integral to the attacks and disseminated across media. Combining scholarship on witnessing and liveness, this article proposes a conceptual framework for understanding perpetrator livestreaming as a witnessing genre, which falls into the three phases pre-mediation, mediation, and re-mediation. Moreover, a prominent example of perpetrator witnessing is analyzed: the livestreaming of the terror attack on two mosques in Christchurch, New Zealand, in 2019.
Using guanxi to conduct elite interviews in China
Authors: Li Hongqin , Harvey William S , Beaverstock Jonathan V
Published: December 2021

Drawing on two research projects in China, this article provides three contributions to the literature on elite interviews. First, we demonstrate how guanxi (informal, particularistic and personal connections) can help gain access and build trust with elite Chinese interviewees in a dynamic rather than a static manner. Second, we show the relational and ongoing process of elite interviewing, combining the sensemaking and sensegiving efforts of the interviewer and interviewee. We introduce the concept of sense-becoming to describe how researchers can develop a sense of strategy for future interviews. Third, we highlight the value of guanxi and co-positionality for the interviewer and interviewee to enhance interaction during interviews. We conclude by providing a heuristic for conceptualising the salience of guanxi and sensemaking for elite interviews in China.
Existentialising existence theory and expanding the sociology of existential milestones
Authors: Inglis David
Published: December 2021

This paper responds to the ‘existence theory’ proposed by Baert, Morgan and Ushiyama. It considers their proposals in light of two main thematics: the general account of human existence, and the more empirical sociology of existential milestones. Both elements are appraised in light of existentialist philosophy and earlier attempts at ‘existentialist sociology’. It is suggested that the authors engage with generational theory, and also give an account of the commodification of significant life-stages by the milestones culture industry.
Vulnerability and existence theory in catastrophic times
Authors: Turner Bryan S.
Published: December 2021

‘Existence theory’ is a bold and imaginative contribution to social theory. Baert, Morgan and Ushiyama (hereafter ‘the authors’) draw on a broad range of existing approaches from Heidegger to Schutz to build a social theory that draws attention to time, the stages of life and the unavoidably precarious nature of human existence. At the same time, they pay careful attention to the social context in which time and existential precariousness combine to form what they call ‘the existential ladder’. Our lives are to some degree measured by the ‘existential milestones’ that we confront over time. These are not invariable stages, but they traditionally included entry into the work force, courtship and marriage, parenthood and maturity, and old age and death. There are in addition norms that attend these transitions. For example, procreation and parenthood are not for the elderly. Old fathers with young children are regarded as foolish if not reprehensible. Failure to pass through the milestones at the appropriate time may result in disappointments, stress and unhappiness.
The Nurse Practitioner Workforce in Western Canada: A Cross-Sectional Practice Analysis Comparison
Authors: Duff E , Golonka Richard , O’ Rourke Tammy , Alraja Abeer A.
Published: December 2021

Regular examination of health workforce data is essential given the pace of health system and legislative changes. Health workforce studies pertaining to nurse practitioner (NP) practice are needed to examine the gaps between work activities, policy, human resource supply, or for population needs. Jurisdictional comparison studies can provide essential information about NP practice for governments to respond to health workforce deficiencies or engage in service planning. In Canada, there is limited provincial-territorial jurisdictional NP workforce data to support health planning or policy change. This descriptive cross-sectional study was to examine the similarities and differences in practice patterns of Canadian NPs. In 2016 and 2017, an electronic survey was sent to all 852 registered NPs in three Canadian provinces, yielding a large convenience sample of 375 NP respondents. The results of this study underscore the value of NPs’ extensive registered nurse expertize as well as their ability to serve diverse patient populations, work in varied healthcare settings, and provide care to medically complex patients. The study findings also show that NPs in all three jurisdictions work to their full scope of practice, in both rural and urban settings. This study is the first to compare NP workforce data across multiple Canadian jurisdictions simultaneously. Studies of this type are valuable tools for understanding the demographics, education, integration, and employment activities of NPs and can aid governments in addressing workforce planning.
Importance of Patient Education for At-home Yoga Practice in Women With Hormonal Therapy-induced Pain During Adjuvant Breast Cancer Treatment: A Feasibility Study
Authors: Faravel Kerstin , Huteau Marie-Eve , Jarlier Marta , de Forges Hélène , Meignant Laetitia , Senesse Pierre , Norton Joanna , Jacot William , Stoebner Anne
Published: December 2021

Background

Osteo-articular pain (OAP) is experienced by approximately 50% of women under hormonal therapy (HT) for breast cancer (BC), which increases the risk for therapy discontinuation. This study was aimed to assess benefits of yoga practice combined with patient education (PE) for at-home practice by evaluating feasibility among BC patients under HT and measuring OAP, flexibility and satisfaction.

Methods

Feasibility was evaluated by patient adherence as accomplishment of at least 4 out of 6 supervised yoga-PE sessions along with 70% or more at-home yoga sessions. Intervention (12 weeks) included two 6-weeks periods: P1 comprising one 90-minutes supervised yoga-PE session/week and 15-minutes daily at-home yoga and P2, daily autonomous at-home yoga sessions. Evaluations (at inclusion and by the end of each period) consisted in assessment of OAP on Visual Analog Scale (VAS), forward flexibility (cm) and patient satisfaction on Likert (0-10 points) scale.

Results

Between September 2018 and May 2019 we included 24 patients of median 53 years (range 36-72). Feasibility was validated by 83% successful adherence rate. Pain was significantly reduced from median VAS of 6 [range 4-10] to 4 [range 0-7] at the end of both P1 and P2 ( p < 0.01), albeit with no difference between P1 and P2. Forward flexibility improved by a median gain of 8 cm (end of P2) and median satisfaction score of 10/10 [range 8-10].

Conclusion

Combined physiotherapy-yoga-PE intervention is a feasible strategy to increase at-home yoga practice with potential benefit on pain, flexibility, and satisfaction, thus prompting further evaluations in larger randomized multicenter trials.

ClinicalTrials.gov

NCT04001751
Paternal Feelings and Child’s Anxiety: The Mediating Role of Father–Child Insecure Attachment and Child’s Emotional Regulation
Authors: Shenaar-Golan Vered , Yatzkar Uri , Yaffe Yosi
Published: December 2021

The study introduces a path model that links between paternal feelings and child’s anxiety symptoms, aiming to test the mediational role of father–child insecure attachment and the child’s difficulties in emotional regulation in the occurrence of anxiety disorders among a sample of 148 fathers and their children (65 boys and 83 girls aged 8–18) attending the child psychiatric center of a public hospital. Participants completed a battery of diagnostical and research questionnaires, including the Parental Feelings Inventory (PFI), the Difficulties in Emotion Regulation Scale (DERS), the Screen for Child Anxiety–Related Emotional Disorders (SCARED), and the Experiences in Close Relationships Scale–Revised Child version (ECR-RC). Using structural equation modeling, we found father’s anger to be associated with father–child anxiety attachment, while the latter simultaneously mediated the link to the child’s anxiety both directly and indirectly (through emotion regulation [ER]). Consistent with previous evidence, we found insecure attachment and emotional regulation to be uniquely associated with the child’s anxiety. The current findings are among the first to demonstrate the interrelations between these variables in the context of father–child relations, suggesting that the child’s exposure to paternal anger might contribute to developing difficulties in ER and elevated anxiety due to a father–child insecure-anxious attachment relationship. The theoretical and practical implications of the findings are discussed in light of parental gender.
Research on sensory comfort of tight-fitting sportswear based on intelligent models
Authors: Cheng Pengpeng , Wang Jianping , Zeng Xianyi , Bruniaux Pascal , Tao Xuyuan , Chen Daoling
Published: December 2021

In order to study the influence of human body parts on the overall comfort under different sports conditions, this paper designed a series of actions such as standing, squatting, running, walking, and so on, and obtained the key parts that affected the overall comfort at every experimental stage (i.e. every motion state) through subjective evaluation. That is, to study and analyze the comfort evaluation of every part and the whole body under different motions conditions, as well as the main parts that affect the overall comfort. In this paper, Analytic Hierarchy Process-Entropy weight, Fuzzy-Rough Set Theory, Analytic Hierarchy Process-Structural Equation Model, and Particle Swarm Optimization-Cuckoo Search were used to optimize the position index. At last, the prediction model of overall comfort was established by Adaptive Network-based Fuzzy Influence System. The input parameters are body part indexes screened by Analytic Hierarchy Process-Entropy weight, Fuzzy-Rough Set Theory, Analytic Hierarchy Process-Structural Equation Model and Particle Swarm Optimization-Cuckoo Search, respectively. And the output is the overall comfort evaluation value. Compared with the real value of overall comfort in every experimental stage, the effectiveness of Analytic Hierarchy Process-Entropy weight, Fuzzy-Rough Set Theory, Analytic Hierarchy Process-Structural Equation Model, and Particle Swarm Optimization-Cuckoo Search optimizing indexes is verified. The results show that: (1) About index optimization models, Particle Swarm Optimization-Cuckoo Search and Analytic Hierarchy Process-Entropy weight are better than Fuzzy-Rough Set Theory, so both Particle Swarm Optimization-Cuckoo Search and Analytic Hierarchy Process-Entropy weight could optimize index predicting overall comfort. (2) Different movements have great differences in the parts that affect the overall comfort.
Level of Sagittal Plane Fit of Plates on the Radial Shaft: A Cadaveric Study Comparing Precontoured and Straight Titanium Plates
Authors: Jones Christopher M. , Stolle Jordan , Ilyas Asif , Siegler Sorin
Published: December 2021

Background:

During radial shaft fracture fixation, it is important to contour the plate appropriately to restore the radial bow in order to maintain normal forearm mechanics and motion. The aim of this study was to investigate the fit of precontoured radial shaft plates versus surgeon-contoured plates.

Methods:

Six 10-hole Acumed® precontoured volar and dorsolateral radius plates and twelve 10-hole Synthes straight titanium 3.5 mm LC-DCP plates were drilled with arrays of 1.5 mm diameter holes to permit measurement of the plate distance off bone. Plates were applied to 6 cadaver radii and secured with a screw on each end. Three plate conditions were tested: precontoured plates, precontoured plates with further surgeon contouring, and straight plates with surgeon contouring. Surgeon contouring time for each plate was recorded. Each plate was divided into 3 equal regions, and the average distance gaps for each region and the entire plate were calculated.

Results:

For the volar side, precontoured plates had a larger total gap compared to that plate with additional surgeon contouring (1.4 mm difference) and the straight surgeon-contoured plates (1.2 mm difference). On the dorsal side, there was no difference in fit between the 3 plate conditions at any location. No differences were found in plate contouring times.

Conclusions:

The precontoured dorsal plate fit was as good as the surgeon-contoured plates indicating this plate could potentially be used in fracture surgery without further bending. The precontoured volar plate was under-contoured, on average, and would likely require further bending to restore the radial bow.
Multilevel analysis of factors associated with HIV among women of reproductive age (15–49 years old) in Ethiopia: Bayesian approach
Authors: Negesse Yilkal , Mankelkl Gosa , Setegn Melsew , Fetene Gossa
Published: December 2021

Background:

Human immunodeficiency virus remains the leading cause of morbidity and mortality throughout the world. Sub-Saharan Africa regions are the most affected regions and accounted for 67% of HIV infections worldwide, and 72% of the world’s AIDS-related deaths.

Objective:

To estimate the prevalence of HIV and identify factors associated with it among women of reproductive age in Ethiopia.

Methods:

This study was conducted based on the 2016 Ethiopian Demographic and Health Surveys data. The data were weighted using sampling weight for probability sampling and non-response to restore the representativeness of the data and get valid statistical estimates. Then, a total of 14,161 weighted sample women were used to investigate the study. Finally, a multilevel analysis was done based on the Bayesian approach to identify factors associated with HIV among women of reproductive age in Ethiopia.

Results:

This study showed the prevalence of HIV among reproductive age group women was 0.85%. Being rural resident (adjusted odds ratio = 0.20; 95% CrI = 0.1–0.4), secondary education level (adjusted odds ratio = 0.20; 95% CrI = 0.1–0.4), rich wealth status (adjusted odds ratio = 4; 95% CrI = 3–6), married women but living separately (adjusted odds ratio = 2.3; 95% CrI = 1.2–4.5), long distance from the health facility (adjusted odds ratio = 0.4; 95% CrI = 0.3–0.5), and exposure to media (adjusted odds ratio = 2.9; 95% CrI = 1.8–4.7) were significantly associated with HIV.

Conclusion:

Being rural residents, women whose marital status is separated, wealthy, travel a long distance to get health facility, and are exposed to media are risky to be infected by HIV. Whereas being a rural resident and educated are preventive factors for HIV. Therefore, the government of Ethiopia and the ministry of health should consider those factors when they design HIV prevention and control strategies.
Supramolecular complexation between cucurbit[7]uril and folate and analytical applications
Authors: Chen Jue , Gao Tengmei , Chang Yinxia , Wei Yanming , Wang Yonghui
Published: December 2021

Folate (FA) plays a key role in the biosynthesis of amino acids, purines, and pyrimidines in the human body, and intracellular folate metabolism has become an attractive target of tumor chemotherapy. In this work, an inclusion interaction was found between FA and cucurbit[7]uril (CB[7]), and the formation of a CB[7]-FA 2:1 supramolecular inclusion complex was confirmed by fluorescence spectra, UV-Vis absorption spectroscopy, 1H NMR, and molecular modeling calculations. In addition, FA is generally determined through the indirect fluorescent method because it shows weak fluorescence in aqueous solution. Therefore, a simple, direct fluorescence probe method for rapidly measuring FA was investigated, and the linear equation of FA was ΔF = 14.691C + 37.366 within the concentration ranges of 0.82 ~ 18.31 µg mL–1. The proposed direct fluorescence method was applied to the determination of spiked plasma. We demonstrated that this method could provide an experimental basis for the targeted administration of the CB[7]-FA complex, and it could be extended as a promising fluorescence detection method for drugs in vivo.
Delivery outcomes as a result of snoring as determined by standard sleep surveys
Authors: Robertson A , Makris A , Johnson P , Middleton S , Norman M , Sullivan C , Hennessy A
Published: December 2021

Background

Sleep-disordered breathing (SDB), is an umbrella term that encompasses obstructive sleep apnea (OSA), central sleep apnea (CSA) and hypoventilation. is common but studies in the pregnant population are limited. Data suggests relationships between OSA and preeclampsia, but the relationship between snoring and pregnancy outcomes is unknown.

Methods

A prospective study of 2224 singleton pregnancies was undertaken. Women were questioned using the Berlin Questionnaire (BQ- 2 or more categories where the score is positive.) and the Epworth Sleepiness Scale (ESS >10/24), the results compared with pregnancy outcomes with regard to hypertension in pregnancy.

Results

Women having symptoms raising the possibility of OSA defined by the BQ with a score >7 was 45.5%, and using ESS with a score >10, was 36%. The birth and neonatal outcomes for self-reported snoring and increased daytime sleepiness showed increased adverse outcomes notably increased caesarean section rates and low APGAR scores but not birth before 37 weeks of gestation.

Conclusion

Using questionnaires designed for the general population, the prevalence of possible undiagnosed OSA is high in the pregnant population. The increased adverse delivery and neonatal outcomes for self-reported snoring and increased daytime sleepiness with these tools indicated the need for further investigation of the links between snoring SDB and pregnancy outcomes.
Innovations in clinical documentation integrity practice: Continual adaptation in a data-intensive healthcare organisation
Authors: Pine Kathleen H , Landon Lee Anne , Bossen Claus , VanGelder ME
Published: December 2021

Background

Numbers of clinical documentation integrity specialists (CDIS) and CDI programs have increased rapidly. CDIS review patient records concurrently with patient admissions and visits to ensure that information is accurate, complete and non-ambiguous, and query clinicians when they see opportunities for improving data. The occupation was initially focused on improving data for reimbursement, but rapid changes to clinical coding requirements, technologies and payment systems led to a quickly evolving role for CDI programs and changes in CDIS practice.

Objective

This case study seeks to uncover the ongoing innovation and adaptation occurring in a CDI program by tracing the evolution of a single CDI program over time.

Method

We present a case study of the CDI program at the HonorHealth hospital system in Arizona.

Results

The HonorHealth CDI program holds a unique hybrid expertise and role within the healthcare organisation that allows it to rapidly adapt to support emergent demands both internal and external to the organisation, such as supporting accurate data collection for the COVID-19 pandemic.

Conclusion

CDIS are a vital component in present data-intensive resourcing efforts. The hybrid expertise of CDIS and capacity for adaption and relationship building has enabled the HonorHealth CDI program to adapt rapidly to meet a growing array of clinical documentation integrity needs, including emergent needs during the COVID-19 pandemic.

Implications

The HonorHealth case study can guide other CDI programs in adaptation of the CDI role and practices in response to changing organisational needs.