bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Environmental Courts on Green Total Factor Productivity in Chinese Cities
Authors: Shao Shuai , Qiao Hongwu
Published: August 2024

As a judicial environmental regulation strategy designed to promote environmental protection, environmental courts have drawn substantial interest. However, whether they can effectively balance the economy and the environment requires further exploration. In this study, we utilized data from 282 Chinese cities from 2004 to 2019 to examine the relationship between environmental courts and green total factor productivity using a multi-period difference-in-differences model. The findings were as follows: (1) Environmental courts led to a notable increase in green total factor productivity. (2) The reduction in carbon intensity and the enhancement of administrative environmental regulation mediated the increase driven by environmental courts. (3) The financial institutions’ support and green technology innovation positively moderated the impact of environmental courts. (4) The role of environmental courts was more pronounced in the western region and in non-low-carbon pilot cities. We explored environmental courts’ effects on green economy development and the internal mechanisms of this, providing policy recommendations to achieve more effective judicial impacts.
Stability Analysis of the Solution for the Mixed Integral Equation with Symmetric Kernel in Position and Time with Its Applications
Authors: Alharbi Faizah M.
Published: August 2024

Under certain assumptions, the existence of a unique solution of mixed integral equation (MIE) of the second type with a symmetric kernel is discussed, in L2[Ω]×C0,T,T<1,Ω is the position domain of integration and T is the time. The convergence error and the stability error are considered. Then, after using the separation technique, the MIE transforms into a system of Hammerstein integral equations (SHIEs) with time-varying coefficients. The nonlinear algebraic system (NAS) is obtained after using the degenerate method. New and special cases are derived from this work. Moreover, numerical results are computed using MATLAB R2023a software.
SC-SA: Byte-Oriented Lightweight Stream Ciphers Based on S-Box Substitution
Authors: Ye Jun , Chen Yabing
Published: August 2024

With the rapid proliferation of the Internet of Things (IoT) in recent years, the number of IoT devices has surged exponentially. These devices collect and transmit vast amounts of data, including sensitive information. Encrypting data is a crucial means to prevent unauthorized access and potential misuse. However, the traditional cryptographic schemes offering robust security demand substantial device resources and are unsuitable for lightweight deployments, particularly in resource-constrained IoT devices. On the other hand, with the automotive industry making strides in autonomous driving, self-driving vehicles are beginning to integrate into people’s daily lives. Ensuring the security of autonomous driving systems, particularly in preventing hacker infiltrations, is a paramount challenge currently facing the industry. An emerging lightweight sequence cipher—aiming to strike a balance between security and resource efficiency—has been proposed in this paper based on S-box substitution and arithmetic addition. The designed security threshold is 280. It has been verified that with a slight performance disadvantage, it can reduce memory usage while ensuring the security threshold. The key stream generated by this structure exhibits excellent pseudo-randomness.
A Novel Design for Joint Collaborative NOMA Transmission with a Two–Hop Multi–Path UE Aggregation Mechanism
Authors: Zhao Xinqi , Chen Hua-Min , Lin Shaofu , Li Hui , Chen Tao
Published: August 2024

With the exponential growth of devices, particularly Internet of things (IoT) devices, connecting to wireless networks, existing networks face significant challenges. Spectral efficiency is crucial for uplink, which is the dominant form of asymmetrical network in today’s communication landscape, in large-scale connectivity scenarios. In this paper, an uplink transmission scenario is considered and user equipment (UE) aggregation is employed, wherein some users act as cooperative nodes (CNs), and help to forward received data from other users requiring coverage extension, reliability improvement, and data–rate enhancement. Non–orthogonal multiple access (NOMA) technology is introduced to improve spectral efficiency. To reduce the interference impact to guarantee the data rate, one UE can be assisted by multiple CNs, and these CNs and corresponding assisted UEs are clustered into joint transmission pairs (JTPs). Interference-free transmission can be achieved within each JTP by utilizing different successive interference cancellation (SIC) decoding orders. To explore SIC gains and maximize data rates in NOMA–based UE aggregation, we propose a primary user CN–based channel–sorting algorithm for JTP construction and apply a whale optimization algorithm for JTP power allocation. Additionally, a conflict graph is established among feasible JTPs, and a greedy strategy is employed to find the maximum weighted independent set (MWIS) of the conflict graph for subchannel allocation. Simulation results demonstrate that our joint collaborative NOMA (JC–NOMA) design with two–hop multi–path UE aggregation significantly improves spectral efficiency and capacity under limited spectral resources.
Structured Light from Classical to Quantum Perspectives
Authors: Bokić Bojana , de Coene Yovan , Ferrara Maria Antonietta , Verbiest Thierry , Caudano Yves , Kolaric Branko
Published: August 2024

Most optical phenomena result from the interaction of electromagnetic waves with matter. However, the light structure can be eminently more complex than plane waves, with many degrees of freedom and dimensions involved, yielding intricate configurations. Light transcends the conventional landscape of electromagnetism, offering the possibility to tailor light in three dimensions (intermixing all three electric field components), in four-dimensional spacetime (for fields manifesting both temporal and spatial patterns), and, beyond that, to make structured quantum light, tuning its characteristics at an unprecedented new level of control. This article addresses the physical foundations of structured light, its interactions with matter, including the nonlinear regime and probing chirality, its classical benefits with holography as a specific highlight, and quantum mechanical applications. It describes the various applications connecting structured light with material physics, quantum information, and technology. Notably, we discuss weak measurements with structured light acting as the meter with connections to probing structured-light beam shifts at interfaces. Ultimately, revealing the interplay between structured light and matter opens attractive avenues for different new technologies and applications, covering both the classical and the quantum realms.
An Assessment of Polycyclic Aromatic Hydrocarbons Using Estimation Programs
Authors: Femi-Oloye Oluwabunmi P. , Sutton Ryen T. , Gordon Heidi D. , Ain Das Ayush , Morenikeji Grace O. , Odorisio Melissa K. , Francestscu Ovidiu D. , Myers Ryan L. , Oloye Femi F.
Published: August 2024

In the environment, the class of chemicals known as polycyclic aromatic hydrocarbons (PAHs) behave somewhat differently. This review covers situations where PAHs can be ‘labile’ and where they can be persistent. The in-silico prediction of toxicity and the properties of selected 29 PAHs were estimated using programs developed by the U.S. Environmental Protection Agency (EPA), such as the Estimation Programs Interface (E.P.I.) and the Toxicity Estimation Software Tool (version 5.1.2) (TEST), with online software such as SwissADME and SwissDock. TEST was used to estimate the LC50 of the fathead minnow (with a range of 14.53 mg/L for 1-indanone and 2.14 × 10−2 mg/L for cyclopenta[c,d]pyrene), the LC50 of Daphnia magna (with a range of 14.95 mg/L for 1-indanone and 7.53 × 10−2 mg/L for coronene), the IGC50 of Tetrahymena pyriformis (with a range of 66.14 mg/L for 1-indanone and 0.36 mg/L for coronene), the bioconcentration factor (8.36 for 1,2-acenaphthylenedione and 910.1 for coronene), the developmental toxicity (0.30 (−) for 1,2-acenaphthylenedione and 0.82 (+) for 4-hydroxy-9-fluorenone), and the mutagenicity (0.25 (−) for 2-methyl-9-fluorenone and 1.09 (+) for coronene). The carbon chain and molecular weight have a significant effect on the properties of PAHs. Overall, it was found that PAHs with a lower molecular weight (LMW) have a higher water solubility and LC50 value and a smaller LogKow value, whereas the opposite is true for heavier PAHs, with TEST predicting that PAHs with an MW of over 168.2 g/mol, with a few exceptions, are mutagenic. Hence, LMW PAHs have a higher potential to be in the environment but are less toxic.
Rattlesnake Crotalphine Analgesic Active on Tetrodotoxin-Sensitive Na+ Current in Mouse Dorsal Root Ganglion Neurons
Authors: Antunes Aurélie , Robin Philippe , Mourier Gilles , Béroud Rémy , De Waard Michel , Servent Denis , Benoit Evelyne
Published: August 2024

Crotalphine is an analgesic peptide identified from the venom of the South American rattlesnake Crotalus durissus terrificus. Although its antinociceptive effect is well documented, its direct mechanisms of action are still unclear. The aim of the present work was to study the action of the crotalid peptide on the NaV1.7 channel subtype, a genetically validated pain target. To this purpose, the effects of crotalphine were evaluated on the NaV1.7 component of the tetrodotoxin-sensitive Na+ current in the dorsal root ganglion neurons of adult mice, using the whole-cell patch-clamp configuration, and on cell viability, using propidium iodide fluorescence and trypan blue assays. The results show that 18.7 µM of peptide inhibited 50% of the Na+ current. The blocking effect occurred without any marked change in the current activation and inactivation kinetics, but it was more important as the membrane potential was more positive. In addition, crotalphine induced an increase in the leakage current amplitude of approximately 150% and led to a maximal 31% decrease in cell viability at a high 50 µM concentration. Taken together, these results point out, for the first time, the effectiveness of crotalphine in acting on the NaV1.7 channel subtype, which may be an additional target contributing to the peptide analgesic properties and, also, although less efficiently, on a second cell plasma membrane component, leading to cell loss.
Continuous and Intermittent Exposure to the Toxigenic Cyanobacterium Microcystis aeruginosa Differentially Affects the Survival and Reproduction of Daphnia curvirostris
Authors: Martínez-Jerónimo Fernando , Gonzalez-Trujillo Lizabeth , Hernández-Zamora Miriam
Published: August 2024

Anthropic eutrophication leads to water quality degradation because it may cause the development of harmful cyanobacterial blooms, affecting aquatic biota and threatening human health. Because in the natural environment zooplankters are exposed continuously or intermittently to cyanotoxins in the water or through cyanobacterial consumption, this study aimed to assess the effects of the toxigenic Microcystis aeruginosa VU-5 by different ways of exposure in Daphnia curvirostris. The acute toxicity produced by the cells, the aqueous crude extract of cells (ACE), and the cell-free culture medium (CFM) were determined. The effect on the survival and reproduction of D. curvirostris under continuous and intermittent exposure was determined during 26 d. The LC50 was 407,000 cells mL−1; exposure to the ACE and CFM produced mortality lower than 20%. Daphnia survivorship and reproduction were significantly reduced. Continuous exposure to Microcystis cells caused 100% mortality on the fourth day. Exposure during 4 and 24 h in 48 h cycles produced adult mortality, and reproduction decreased as the exposure time and the Microcystis concentrations increased. The higher toxicity of cells than the ACE could mean that the toxin’s absorption is higher in the digestive tract. The temporary exposure to Microcystis cells produced irreversible damage despite the recovery periods with microalgae as food. The form and the continuity in exposure to Microcystis produced adverse effects, warning about threats to the zooplankton during HCBs.
Convolutional Neural Network Processing of Radio Emission for Nuclear Composition Classification of Ultra-High-Energy Cosmic Rays
Authors: Calafeteanu Tudor Alexandru , Isar Paula Gina , Sluşanschi Emil Ioan
Published: August 2024

Ultra-high-energy cosmic rays (UHECRs) are extremely rare energetic particles of ordinary matter in the Universe, traveling astronomical distances before reaching the Earth’s atmosphere. When primary cosmic rays interact with atmospheric nuclei, cascading extensive air showers (EASs) of secondary elementary particles are developed. Radio detectors have proven to be a reliable method for reconstructing the properties of EASs, such as the shower’s axis, its energy, and its maximum (Xmax). This aids in understanding fundamental astrophysical phenomena, like active galactic nuclei and gamma-ray bursts. Concurrently, data science has become indispensable in UHECR research. By applying statistical, computational, and deep learning methods to both real-world and simulated radio data, researchers can extract insights and make predictions. We introduce a convolutional neural network (CNN) architecture designed to classify simulated air shower events as either being generated by protons or by iron nuclei. The classification achieved a stable test error of 10%, with Accuracy and F1 scores of 0.9 and an MCC of 0.8. These metrics indicate strong prediction capability for UHECR’s nuclear composition, based on data that can be gathered by detectors at the world’s largest cosmic rays experiment on Earth, the Pierre Auger Observatory, which includes radio antennas, water Cherenkov detectors, and fluorescence telescopes.
From the Janis–Newman–Winicour Naked Singularities to the Einstein–Maxwell Phantom Wormholes
Authors: Gao Changjun , Qiu Jianhui
Published: August 2024

The Janis–Newman–Winicour spacetime corresponds to a static spherically symmetric solution of Einstein equations with the energy momentum tensor of a massless quintessence field. It is understood that the spacetime describes a naked singularity. The solution has two parameters, b and s. To our knowledge, the exact physical meaning of the two parameters is still unclear. In this paper, starting from the Janis–Newman–Winicour naked singularity solution, we first obtain a wormhole solution by a complex transformation. Then, letting the parameter s approach infinity, we obtain the well-known exponential wormhole solution. After that, we embed both the Janis–Newman–Winicour naked singularity and its wormhole counterpart in the background of a de Sitter or anti-de Sitter universe with the energy momentum tensor of massive quintessence and massive phantom fields, respectively. To our surprise, the resulting quintessence potential is actually the dilaton potential found by one of us. It indicates that, by modulating the parameters in the charged dilaton black hole solutions, we can obtain the Janis–Newman–Winicour solution. Furthermore, a charged wormhole solution is obtained by performing a complex transformation on the charged dilaton black hole solutions in the background of a de Sitter or anti-de Sitter universe. We eventually find that s is actually related to the coupling constant of the dilaton field to the Maxwell field and b is related to a negative mass for the dilaton black holes. A negative black hole mass is physically forbidden. Therefore, we conclude that the Janis–Newman–Winicour naked singularity solution is not physically allowed.
Re-Emergence of DENV-3 in French Guiana: Retrospective Analysis of Cases That Circulated in the French Territories of the Americas from the 2000s to the 2023–2024 Outbreak
Authors: Lagrave Alisé , Enfissi Antoine , Tirera Sourakhata , Demar Magalie Pierre , Jaonasoa Jean , Carod Jean-François , Ramavoson Tsiriniaina , Succo Tiphanie , Carvalho Luisiane , Devos Sophie , Dorleans Frédérique , Leon Lucie , Berlioz-Arthaud Alain , Musso Didier , Lavergne Anne , Rousset Dominique
Published: August 2024

French Guiana experienced an unprecedented dengue epidemic during 2023–2024. Prior to the 2023–2024 outbreak in French Guiana, DENV-3 had not circulated in an epidemic manner since 2005. We therefore studied retrospectively the strains circulating in the French Territories of the Americas (FTA)—French Guiana, Guadeloupe, and Martinique—from the 2000s to the current epidemic. To this end, DENV-3 samples from the collection of the National Reference Center for Arboviruses in French Guiana (NRCA-FG) were selected and sequenced using next-generation sequencing (NGS) based on Oxford Nanopore Technologies, ONT. Phylogenetic analysis showed that (i) the 97 FTA sequences obtained all belonged to genotype III (GIII); (ii) between the 2000s and 2013, the regional circulation of the GIII American-I lineage was the source of the FTA cases through local extinctions and re-introductions; (iii) multiple introductions of lineages of Asian origin appear to be the source of the 2019–2021 epidemic in Martinique and the 2023–2024 epidemic in French Guiana. Genomic surveillance is a key factor in identifying circulating DENV genotypes, monitoring strain evolution, and identifying import events.
Whole-Genome Analysis of the Influenza A(H1N1)pdm09 Viruses Isolated from Influenza-like Illness Outpatients in Myanmar and Community-Acquired Oseltamivir-Resistant Strains Present from 2015 to 2019
Authors: Chon Irina , Win Su Mon Kyaw , Phyu Wint Wint , Saito Reiko , Kyaw Yadanar , Win Nay Chi , Lasham Di Ja , Tin Htay Htay , Tamura Tsutomu , Otoguro Teruhime , Wagatsuma Keita , Sun Yuyang , Li Jiaming , Watanabe Hisami
Published: August 2024

In this study, we describe the genetic characteristics of influenza A(H1N1)pdm09 strains detected in Myanmar from 2015 to 2019. Whole genomes from 60 A(H1N1)pdm09 virus isolates were amplified using real-time polymerase chain reaction and successfully sequenced using the Illumina iSeq100 platforms. Eight individual phylogenetic trees were retrieved for each segment along with those of the World Health Organization (WHO)-recommended Southern Hemisphere vaccine strains for the respective years. A(H1N1)pdm09 viruses from 2015 were found to belong to clade 6B, those from 2016 to 6B.1, 2017 to 6B.1A, and 2019 to 6B.1A.5a, and were genetically distinct from the Southern Hemisphere vaccine strains for the respective seasons, A/California/7/2009 and A/Michigan/45/2015. We observed one virus with intra-subtype reassortment, collected in the 2015 season. Importantly, three viruses possessed the H275Y substitution in the neuraminidase protein, appearing to be community-acquired without the prior administration of neuraminidase inhibitors. These viruses exhibited highly reduced susceptibility to oseltamivir and peramivir. This study demonstrates the importance of monitoring genetic variations in influenza viruses that will contribute to the selection of global influenza vaccines.
Booster Vaccination with BNT162b2 Improves Cellular and Humoral Immune Response in the Pediatric Population Immunized with CoronaVac
Authors: Díaz-Dinamarca Diego A. , Cárdenas-Cáceres Simone , Muena Nicolás A. , Díaz Pablo , Barra Gisselle , Puentes Rodrigo , Escobar Daniel F. , Díaz-Samirin Michal , Santis-Alay Natalia T. , Canales Cecilia , Díaz Janepsy , García-Escorza Heriberto E. , Grifoni Alba , Sette Alessandro , Tischler Nicole D. , Vasquez Abel E.
Published: August 2024

The SARS-CoV-2 Omicron variant and its sublineages continue to cause COVID-19-associated pediatric hospitalizations, severe disease, and death globally. BNT162b2 and CoronaVac are the main vaccines used in Chile. Much less is known about the Wuhan-Hu-1 strain-based vaccines in the pediatric population compared to adults. Given the worldwide need for booster vaccinations to stimulate the immune response against new Omicron variants of SARS-CoV-2, we characterized the humoral and cellular immune response against Omicron variant BA.1 in a pediatric cohort aged 10 to 16 years who received heterologous vaccination based on two doses of CoronaVac, two doses of CoronaVac (2x) plus one booster dose of BNT162b2 [CoronaVac(2x) + BNT162b2 (1x)], two doses of CoronaVac plus two booster doses of BNT162b2 [CoronaVac(2x) + BNT162b2 (2x)], and three doses of BNT162b2. We observed that the [CoronaVac(2x) + BNT162b2 (2x)] vaccination showed higher anti-S1 and neutralizing antibody titers and CD4 and CD8 T cell immunity specific to the Omicron variant compared to immunization with two doses of CoronaVac alone. Furthermore, from all groups tested, immunity against Omicron was highest in individuals who received three doses of BNT162b2. We conclude that booster vaccination with BNT162b2, compared to two doses of CoronaVac alone, induces a greater protective immunity.
Understanding Two Decades of Turbidity Dynamics in a Coral Triangle Hotspot: The Berau Coastal Shelf
Authors: Khadami Faruq , Tarya Ayi , Radjawane Ivonne Milichristi , Suprijo Totok , Sujatmiko Karina Aprilia , Anwar Iwan Pramesti , Hidayatullah Muhamad Faqih , Erlangga Muhamad Fauzan Rizky Adisty
Published: August 2024

Turbidity serves as a crucial indicator of coastal water health and productivity. Twenty years of remote sensing data (2003–2022) from the Aqua Moderate Resolution Imaging Spectroradiometer (MODIS) satellite were used to analyze the spatial and temporal variations in turbidity, as measured by total suspended matter (TSM), in the Berau Coastal Shelf (BCS), East Kalimantan, Indonesia. The BCS encompasses the estuary of the Berau River and is an integral part of the Coral Triangle, renowned for its rich marine and coastal habitats, including coral reefs, mangroves, and seagrasses. The aim of this research is to comprehend the seasonal and interannual patterns of turbidity and their associations with met-ocean parameters, such as wind, rainfall, and climate variations like the El Niño–Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD). The research findings indicate that the seasonal spatial pattern of turbidity is strongly influenced by monsoon winds, while its temporal patterns are closely related to river discharge and rainfall. The ENSO and IOD climate cycles exert an influence on the interannual turbidity variations, with turbidity values decreasing during La Niña and negative IOD events and conversely increasing during El Niño and positive IOD events. Furthermore, the elevated turbidity during negative IOD and La Niña coincides with rising temperatures, potentially acting as a compound stressor on marine habitats. These findings significantly enhance our understanding of turbidity dynamics in the BCS, thereby supporting the management of marine and coastal ecosystems in the face of changing climatic and environmental conditions.
The Development of Natural and Cultural Tourism in Buku Limau Island Based on Social Networking
Authors: Saputra Putra Pratama , Bahtera Novyandra Ilham , Hayati Laila
Published: August 2024

The local authorities are promoting Buku Limau Island as an emerging tourist site. The island's distinguishing features include stunning coral reefs, picturesque white sandy beaches, and its role as a hub for the production of salted and fresh seafood. The objective of this study is to identify and describe the natural and cultural attractions on Buku Limau Island, particularly in the Manggar Subdistrict of East Belitung Regency. Additionally, the study seeks to examine social networks in order to facilitate the development and expansion of natural and cultural tourism destinations in the area. This research employs a mixed-method approach, utilizing data gathering approaches such as observation, focus group discussions (FGD), and surveys administered through questionnaires. UCINET program was used to conduct descriptive qualitative analysis and social network analysis to identify and reveal tourist characteristics. This is followed by the breakdown and study of social networks among stakeholders and interest groups. The findings of this study indicate that Buku Limau Island exhibits attributes of both natural and cultural tourism, with the predominant population of fishermen being of Bugis ethnicity. The identification and study of social networks demonstrate that stakeholders have formed networks to actively support and cultivate tourism attractions, encompassing both natural and cultural aspects. Nevertheless, there are still certain stakeholders who have not been engaged in the network throughout the process of developing and improving the tourism destination.  The research limits are deliberately established to enhance the study's focus and depth. The information and data acquired are directly relevant to the fundamental issue of this investigation. The scope of this study is limited to the creation of natural and cultural tourism centered around social networks on Buku Limau Island. Theoretical implications shed light on the ideas of local government assistance, social networks, and tourist attractions. Meanwhile, the practical consequences surely affect the government, tourism stakeholders, and the community in their efforts to promote the growth of natural and cultural tourism through social networks on Buku Limau Island.
Âşık Şenlik’in Şiirlerinde Varoluşsal İzler
Authors: Aslan Erkan
Published: August 2024

Kapsam ve sınırlılıklarının yanı sıra tanım ve niteliği konusunda da ortak bir noktada buluşmanın zor olduğu varoluş düşüncesi, var olma olgusunu genel olarak karamsar bir tarzda ele alan, felsefe tarihi açısından önemli düşünce akımıdır. Birçok farklı tema etrafında şekillenen varoluş düşüncesini, edebî ve sanatsal akımların yanı sıra bir kültür ekolü olan âşıklık geleneği içerisinde de görmek mümkündür. Çoğu âşık, yaşadığı varoluşsal kaygılara şiirlerinde yer vererek âdeta varoluş düşüncesinin toplumsal niteliğine de ışık tutmaktadır. Bu çalışmada da Kars âşık ekolünün kurucu âşığı Şenlik’in şiirlerinde yer alan varoluşçu temalar, toplumsal ve psikolojik boyutlarıyla incelemeye tabi tutulmuştur. İnceleme; “yalnızlık ve yabancılaşma”, başkaldırı”, “ölüm”, “hiçlik”, “kaygı-acı çekme” temaları ışığında ele alınmış ve Âşık Şenlik’te varoluş düşüncesinin geniş bir şekilde yer bulduğu tespit edilmiştir. Şenlik’te görülen gurbet kaynaklı yalnızlık, içsel sıkıntılar, sosyal hayata karşı yapılan eleştiriler ve nihayet bir kurtuluş parolası olarak ölüm gibi varoluşsal izler, yaşadığı toplumun bilinçdışının yansıması olarak ortaya çıkmakta ve toplumsal bir boyuta dönüşmektedir. Şenlik’te yer alan varoluşsal kaygıların yaşadığı toplumun düşüncelerine de uygun bir şekilde ateist değil teist bir yapıda olduğu görülmektedir. Yine Âşık Şenlik üzerinden, varoluş düşüncesinin toplumsal ve psikolojik boyutunun incelendiği bu çalışmadaki sonuçların, âşık edebiyatına mensup birçok âşık için söylenebilir olduğu sonucuna ulaşılmıştır.
Âşık Veysel’in Hayatı ve Şiirlerinden Hareketle Toplumsal Eşit(siz)lik ve Tabakalaşma
Authors: Öztürk Aykaç Nilüfer
Published: August 2024

Bu çalışmada son dönem Türk halk ozanlarından Âşık Veysel’in hayatı ve şiirleri, toplumsal eşit(siz)lik ve tabakalaşma temaları açısından ele alınmıştır. Bu bağlamda nitel araştırma yöntemlerinden tematik analiz ve içerik analizi teknikleri kullanılmış; ayrıca edebiyat sosyolojisinin “yazar” ve “eser” unsurları özelinde inceleme derinleştirilmiştir. Çalışmanın odağında, toplumsal tabakalaşma ve eşit(siz)lik temalarına ilişkin tematik bir inceleme bulunmaktadır. Analiz birimi olarak bu temalarla ilgili Âşık Veysel’in biyografisinde yer alan anılar ve bu temaların yer aldığı şiirler incelemeye tabi tutulmuştur. Toplumsal eşitsizlik ve tabakalaşmaya ilişkin örnekler, ilk olarak “maddi sebepler kaynaklı eşitsizlikler” ve “ırk, etnik köken ve mezhepsel kimlik kaynaklı eşitsizlikler” olmak üzere iki ayrı grupta sınıflandırılmıştır. Bu kategorilerde yer alan unsurların insanlar arasında ayrımcılık oluşturması, Veysel tarafından eleştirilmektedir. Üçüncü bir kategori olarak özellikle meslekler ve karakterlere göre toplumsal farklılıklar ele alınmış, Veysel’in bunlara “farklılık” temelindeki yaklaşımı yorumlanmıştır. İncelemelerde Marksist eleştiri, alan teorisi, sembolik etkileşimcilik gibi teorik yaklaşımlardan da faydalanılmıştır. Bu makale aracılığıyla Âşık Veysel’in bir ozan olarak toplumsal duyarlılığı yorumlanmış, bundan hareketle edebiyatın toplumsal meseleleri ele alışı örneklendirilmiş ve tartışılmıştır.
Impacto do exercício físico no ventrículo esquerdo em indivíduos com Diabetes Mellitus tipo 2: uma revisão de literatura
Authors: Braga Luisa Reis , Salles Arthur Leitão , Ricardo Arthur Souza Diniz , Batista Camily de Aguiar , Gomes Clara Maia , Ávila Giovana Costa Machado de , Barbosa Maria Alice Borges , Barroso Raquel Cristina Villar
Published: August 2024

Introdução: Diabetes Mellitus (DM) é uma doença causada pela produção insuficiente ou má absorção de insulina. A insuficiência de atividade física em indivíduos com Diabetes Mellitus Tipo 2 (DM2) frequentemente resulta em insuficiência cardíaca, uma complicação cardiovascular. Objetivo: descrever, conforme a literatura, os efeitos da atividade física no ventrículo esquerdo (VE) de pessoas com DM2, relacionando o exercício a uma ação cardioprotetora eficaz. Metodologia: Foi realizada uma revisão integrativa utilizando artigos das bases de dados PubMed, Cochrane e Scielo, com as palavras-chave "Exercício físico", "Diabetes tipo 2" e "Ventrículo esquerdo". 16 artigos publicados entre 2002 e 2023 foram incluídos. Resultados: Evidências de melhorias em torção máxima, deformação longitudinal global, taxa de deformação global, tempo até a taxa de distorção máxima, taxa de enchimento diastólico precoce, taxa de deformação diastólica precoce máxima e um aumento na fração de ejeção do ventrículo esquerdo foram encontradas em adultos com DM2 que praticavam regularmente exercícios físicos. O treinamento de resistência e os exercícios aeróbicos foram as principais atividades associadas ao aprimoramento desses parâmetros. Os benefícios foram relacionados tanto à prática constante de curto prazo quanto de longo prazo, especialmente envolvendo atividades de intensidade moderada e alta. Conclusão: A literatura atual relaciona a prática regular de diferentes tipos de exercícios físicos a várias melhorias estruturais e fisiológicas relacionadas ao ventrículo esquerdo de pessoas com DM2, estabelecendo a atividade física como um efeito cardioprotetor no ventrículo esquerdo. No entanto, estudos existentes analisam diferentes variáveis, dificultando a comparação de resultados.
Psicose de difícil controle em paciente com bipolaridade e apnéia do sono após COVID-19: um relato de caso
Authors: Costa Gisele Vasconcelos Calheiros de Oliveira , Costa Alessa Moísa Barros , Medeiros Alba Letícia Peixoto , Costa George Vasconcelos Calheiros de Oliveira , Peixoto Audenis Lima de Aguiar
Published: August 2024

O quadro de transtorno afetivo bipolar (TAB) tem como definição clássica a alternância entre o estado de mania ou hipomania e episódios depressivos. Além disso, é comum que pacientes com bipolaridade apresentem distúrbios do sono, como a Síndrome da Apneia Obstrutiva do Sono (SAOS). Em 2019, os distúrbios psiquiátricos ganharam destaque, sob uma nova visão, devido à correlação com a infecção com o SARS-Cov-2. O objetivo deste trabalho é relatar um caso de TAB com psicose que foi agravado pela SAOS e COVID-19. Nesse cenário, foi observado que a SAOS é considerada um fator de risco para COVID-19 e a associação de ambas patologias pode gerar risco para descompensação psiquiátrica.
Diabetes insipidus central secundária a histiocitose maligna: um relato de caso
Authors: Prado Eduardo Henrique Meneses , Gonçalves Ana Luiza Faria , Tarabal Dafne Gonçalves Nogueira , Rezende Neto Geraldo Morais
Published: August 2024

Introdução: A histiocitose de células de Langerhans (HCL) é um distúrbio raro do sistema fagocitário mononuclear, caracterizado pela proliferação excessiva de células dendríticas. Uma das manifestações frequentes é o diabetes insipidus central (DIC), resultante da destruição dos neurônios hipotalâmicos produtores de arginina vasopressina (AVP), que se manifesta com poliúria. Relato de caso: paciente feminina, 58 anos com diabetes mellitus tipo 2 e histórico de histiocitose maligna, admitida com quadro de hiperglicemia grave e poliúria intensa. Após tratamento inicial para controlar os níveis glicêmicos e hidratação, persistiu desorientada e hipernatrêmica, sendo diagnosticada com DIC. Exames anteriores revelaram ressecção parcial da histiocitose e tratamento quimioterápico, destacando a correlação entre DIC e histiocitose. Discussão: o diagnóstico de DIC secundária à histiocitose envolve anamnese detalhada, exame físico e exames complementares. O manejo inclui terapia com desmopressina para controlar os sintomas, uma vez que a reversão completa do DIC é rara. A complexidade diagnóstica e as potenciais complicações graves sublinham a importância de considerar a histiocitose como um diagnóstico diferencial em pacientes com DIC, facilitando intervenções precoces e adequadas.  Conclusão: o DIC é uma doença rara e de difícil diagnóstico. Esse relato demonstra a importância de uma história clínica bem detalhada e reforça a importância da análise dos diagnósticos diferenciais possíveis.
Avaliação do conhecimento anatômico humano após a conclusão da disciplina de anatomia entre os estudantes de medicina de uma instituição de ensino superior
Authors: Annuzzo Miguel de Sousa e , Ribeiro Guilherme Augusto Turbino , Silva Adriana Torres da
Published: August 2024

Introdução: A Anatomia Humana é uma das disciplinas básicas da medicina. Seu conteúdo, geralmente, é descrito como complexo, devido à memorizações extensas. Contudo, atualmente defende-se a adoção de metodologias ativas e promotoras do aprendizado significativo, memorizado de forma compreensiva e com aplicabilidade funcional. Objetivo: Avaliar o conhecimento sobre a Anatomia Humana após a conclusão da diciplina entre estudantes de uma faculdade de Medicina de Minas Gerais. Métodos: Trata-se de um estudo transversal, que contou com um questionário aplicado a 268 alunos de ambos os sexos, matriculados do 3º ao 12º período do curso de medicina dessa faculdade. Resultados: Quando questionados sobre a frequência no laboratório de anatomia durante a disciplina, 38% dos alunos frequentavam apenas durante as aulas práticas; 8% durante as aulas práticas e em outros horários todas as semanas; 33% durante as aulas práticas e na véspera das provas e 20% durante as aulas práticas, em outros horários ao longo da semana e na véspera das provas. Com relação ao hábito de revisar os conteúdos prévios, 16% dos alunos reportaram revisar com frequência, 48% revisam pouco e 34% não revisam. Quando questionados sobre o desempenho ao cursar a disciplina e o conhecimento atual, observou-se redução. Ao correlacionar essa diminuição com o hábito de revisar os conteúdos, verificou-se relação significativa, diferentemente na correlação com a frequência no laboratório de anatomia durante o curso da disciplina. Conclusão: A revisão dos conteúdos se mostrou um aliado no aprendizado eficaz, diferentemente da frequência ao laboratório de anatomia ao longo da disciplina.
Clampeamento tardio de cordão umbilical em gestantes com diagnóstico de HIV
Authors: Bezerra Matheus Guilherme , Almeida Walerya Gonçalves de , Moreira Caio Oliveira , Almeida Yanca Rodrigues de , Machado Junior Benjamim Arnaldo Morais Nunes , Silva Carolina Muniz e , Reis Aline Silva , Santana Natália Oliveira , Han Izabella Kimel Pessato , Han Lucas Yunzhi Pessato , Liz Kleifer Francisco de , Brito Bruna Rojo
Published: August 2024

É apontado ainda que ao depender da forma como a notícia do diagnóstico foi passada o impacto se tornou maior, muitas relataram choque, acompanhado de medo e pânico, tristeza e desesperança, tendo em vista, que a maioria delas associaram o HIV a uma sentença de morte e logo passaram a apresentarem uma preocupação constante de contaminar as pessoas que amavam e afetar nesse processo também a criança e o risco de transmissão. O corte do cordão umbilical em gestantes com HIV deve ser realizado com cuidado para minimizar o risco de transmissão vertical do vírus para o bebê. Uso de Terapia Antirretroviral - TARV. Administração de AZT;  .Essas medidas são Se você tiver mais dúvidas ou precisar de informações específicas, é sempre bom consultar um profissional de saúde especializado.
Uso de AAS e cálcio na profilaxia da Pré – Eclâmpsia
Authors: Bezerra Mairiel Leila de Deus , Almeida Walerya Gonçalves de , Moreira Caio Oliveira , Machado Junior Benjamim Arnaldo Morais Nunes , Sousa Lorrane Brasil de Andrade , Silva Carolina Muniz e , Han Izabella Kimel Pessato , Han Lucas Yunzhi Pessato , Forin João Vitor de Queiroz , Liz Kleifer Francisco de , Brito Bruna Rojo
Published: August 2024

O presente estudo tem como objetivo estudar a associação doses de ácido acetilsalicílico ( AAS) e Cálcio ( 2g/ dia) na prevenção da pré-eclâmpsia (PE), em gestantes. Existem muitas variáveis que divergem entre os autores e que influenciam no benefício do tratamento, como: dose terapêutica, período de início, seleção de um grupo de gestantes ideal e horário da ingestão do medicamento Nossos resultados não permitem apoiar o uso de AAS, associada ao cálcio, em gestantes hipertensas crônicas selecionadas pela dopplervelocimetria das artérias uterinas, na prevenção da pré-eclâmpsia. Em relação aos aspectos medológicos, trata-se de revisão de literatura. Foi observada uma redução significante na freqüência de RCIU a favor da utilização das medicações associadas.
Repercussões da pandemia da COVID-19 na atenção primária à saúde de um município baiano
Authors: Costa Vitor Gabriel Dantas , Santana Maria Eduarda de Souza , Costa Iasmin Dantas , Fernandes Elionara Teixeira Boa Sorte
Published: August 2024

Objetivo: Analisar as repercussões da pandemia nos atendimentos da Atenção Primária à Saúde (APS) de um município do sudoeste baiano. Método: Estudo qualitativo, realizado em 2022 com vinte e dois profissionais da área da saúde de um município do sudoeste baiano. Os dados foram coletados por meio de entrevista semiestruturada e a análise dos dados foi fundamentada na análise de conteúdo de Bardin. Resultados: Os profissionais da saúde apontaram impactos da pandemia em relação à organização das unidades, adesão dos pacientes, complicações de doenças crônicas e um prejuízo significativo para os programas de cuidado continuado. Em relação às ações desenvolvidas, a criação de mecanismos para contato com a população mostrou-se positivo. Conclusão: A pandemia apresentou uma repercussão negativa na assistência à saúde nas APS representada pela redução da procura e aumento de comorbidades.
Pneumotoráx hipertensivo: da fisiopatologia à intervenção
Authors: Costa Igor Fernando , Carnelós Luísa Ribeiro , Pereira Priscilla Aparecida Tartari , Galves Taiana Cáira Barbosa
Published: August 2024

O pneumotórax hipertensivo é uma emergência médica caracterizada pela presença de ar no espaço pleural, com aumento da pressão torácica, podendo comprometer os sistemas cardiovascular e respiratório, causando sequelas graves e até mesmo óbito. O diagnóstico é baseado em achados clínicos e confirmado por meio de exames de imagem, que orientam o tratamento para alívio da pressão intratorácica e reestabelecimento da hemodinâmica. Apesar dos avanços no diagnóstico e tratamento, o conhecimento da fisiopatologia é fundamental na busca por estratégias que melhorem o manejo clínico, reduzindo as taxas de morbidade e mortalidade. Este trabalho propõe uma revisão crítica da literatura existente sobre o pneumotórax hipertensivo, destacando avanços no manejo e principais métodos de abordagem e diagnóstico, com estudos acerca do quadro clínico, etiologia e alternativas terapêuticas. Conclui-se ser essencial o conhecimento técnico e clínico sobre a fisiopatologia e alternativas de intervenção para o cuidado imediato e integral dos pacientes com pneumotórax hipertensivo.
Germinação e vigor na cultura do milho sob tratamento com bioestimulante para sementes
Authors: Costa Marianne Paula Santos da , Sousa Marília Caixeta , Brandão Fernando João Bispo , Ormond Antonio Tassio Santana , Silva Magnun Antonio Penariol da , Matos Victor Arlindo Taveira de
Published: August 2024

Os tratamentos de sementes promovem um melhor desenvolvimento das plantas, visando maior vigor e produtividade, além de favorecer uma melhor expressão genética e hormonal. Esta pesquisa teve como objetivo analisar o efeito de diferentes doses de um fertilizante organomineral no tratamento de sementes, com foco na melhoria do desenvolvimento inicial das plântulas. Os tratamentos foram acompanhados diariamente por sete dias, com o objetivo de verificar o índice de velocidade de germinação, porcentagem de germinação, porcentagem de plântulas normais e anormais, comprimento de parte aérea, comprimento radicular, massa fresca e seca das plântulas e o volume de raiz. Para isso foram feitos cinco (5) tratamentos, com diferentes doses do fertilizante organomineral Emerge®, cada um com quatro (4) repetições: T1- Testemunha (0,0 mL/kg de semente); T2 – 2,0 mL/kg de semente; T3- 4,0 mL/kg de semente; T4- 6,0 mL/kg de semente; T5- 8,0 mL/kg de semente. Cada repetição consistiu em 50 sementes, totalizando 200 sementes por tratamento. Os testes foram realizados em papel germiteste, em laboratório, sob condições controladas. Os resultados indicam que o uso do fertilizante não comprometeu a capacidade germinativa nem o vigor das sementes de milho. O tratamento T5 destacou-se por proporcionar um comprimento da parte aérea significativamente maior em comparação aos tratamentos T1  e T2. O tratamento T2, por sua vez, apresentou as maiores massas fresca e seca de raiz em relação à testemunha. Além disso, os tratamentos T2, T4 e T5 resultaram em volumes de raiz significativamente superiores à testemunha, com incrementos de até 40%.
Tolerancia intrínseca de Bacillus subtilis a diferentes concentraciones de cipermetrina de uso doméstico
Authors: Díaz Laura Denisse Santander , Puerto Lourdes Carolina Cardozo del , Balbuena Alicia Belén Acuña , Barberán María Gabriela Figueredo , Fariña Domitila Villalba , Silva Shaun Patrick McGahan , Arrúa Silverio Andrés Quintana , Alvarenga Andrea Alejandra Arrúa , Rodas Gilberto Antonio Benítez
Published: August 2024

La utilización masiva de insecticidas como la cipermetrina, en entornos urbanos y agrícolas ha generado preocupaciones debido a su persistencia en el suelo y su potencial daño a organismos no-objetivos. A pesar de su toxicidad y durabilidad de estos productos, algunas bacterias, como Bacillus subtilis, han demostrado tener vías catabólicas capaces de utilizar la cipermetrina como fuente de carbono y energía. En este contexto, el presente estudio se centró en la evaluación general de la tolerancia de B. subtilis, una cepa aislada en Paraguay, a diferentes concentraciones de cipermetrina de uso doméstico y bajo condiciones controladas no reportadas aún en el país para tales propósitos. La investigación destacó cómo diferentes concentraciones de cipermetrina influyeron en la cinética de crecimiento de B. subtilis y cómo estas se correlacionaron entre sí. Los resultados indicaron una notable disminución en el crecimiento bacteriano a concentraciones más altas de cipermetrina, señalando una adaptación reducida de la bacteria a medida que la concentración del insecticida aumenta. Este hallazgo tiene implicaciones significativas, en la comprensión de la adaptabilidad de una cepa nativa y en la estandarización de métodos biotecnológicos con fines ecológicos aplicables para la gestión adecuada de residuos de cipermetrina.
Automated Interpretation Of The Tandem Mass Spectra Of Peptides Using Artificial Neural Networks
Authors:   ,   Cork Institute of Technology, Manning Timothy
Published: August 2024

"The manual interpretation of mass spectra is a complex and time consuming task. The problem of manually interpreting this data is further exacerbated by the large numbers of mass spectra which can potentially be produced in a single proteoniics experiment. This shows the need for high throughput approaches to the interpretation of mass spectra. Existing automated approaches are however error prone due to the complexity of the task. Accordingly, this thesis discusses and evaluates the application of neural networks to improving the sensitivity, specificity and robustness of current approaches to the automated interpretation of such mass spectral data. Several neural network approaches and architectures are evaluated in an attempt to define a neural network suited to the interpretation of the mass spectral data of peptides. The best performing networks are evaluated on their potential to offer a lift in performance to elements of the current non-neural network based approaches to the interpretation of the mass spectra of peptides. A novel automated peptide sequencing application is developed which relies heavily on the output produced by the neural network at all stages of its process. This application allows for an assessment of the capability of neural networks in the domain and the identification of tasks to which neural networks offer superior performance. The neural networks developed in this research attain high levels of performance and robustness. Good results were achieved in terms of both sensitivity and specificity on the task of mass spectral peak classification. Despite the overall good performance attained for the neural network, generally inferior performance was observed for the novel peptide sequencing application when benchmarked against classical (non-neural network based) automated approaches. The results attained are however promising with several instances observed of superior performance to the PepNovo sequencing application."