bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of DNA methylation on thyroglobulin gene expression in thyroid pathology
Authors: Turakulov Y. Kh. , Kadyrov D. A. , Atakhanova B. A.
Published: October 2019

Effect of methylation of different DNA domains on gene expression can manifest at all regulatory levels involved in this process: at the level of transcription and posttranscription, translation and posttranslation. Study of the relationship between DNA methylation and thyroglobulin (TH) gene expression in some thyroid diseases is needed for understanding the mechanisms regulating genetic information in general.

The aim of this study was to investigate the effect of DNA methylation on TH gene expression in thyroid disease. We investigated the probability of contribution of DNA methylation to regulation of TH gene expression. TH gene methylation was studied in nodular euthyroid and diffuse toxic goiter and in thyroid cancer. The 5'-flanking domain of the gene, containing sequences recognized by Hpa 11 and MspI restrictases, was analyzed. The 5'-flanking domain of TH gene is hypermethylated in thyroid cancer. These data indicate an inverse correlation between TH gene expression and methylation.
Current methods for diagnosis of primary hyperparathyroidism (a lecture)
Authors: Kotova I. V. , Kalinin A. P.
Published: October 2019

The article is devoted to the current methods for diagnosis of primary hyperparathyroidism
Oxidative stress: clinical and metabolic parameters and a polymorphic marker of the catalase gene in the development of retinopathy in patients with type II diabetes
Authors: Bulatova O. S. , Kondratiev Y. Yu. , Milenkaya T. M. , Balabolkin M. I. , Mamaev G. G. , Chistyakov D. A. , Turakulov R. I. , Nosikov V. V. , Dedov I. I.
Published: October 2019

General clinical and ophthalmological parameters, serum lipids and lipid peroxides are studied in 43 patients with type 2 diabetes mellitus (non-insulin-dependent diabetes NIDDM). The activity of erythrocyte superoxide dismutase (SOD) and incidence of alleles of catalase (CA T) gene polymorphous marker, two key enzymes in antioxidant defense, are assessed. The patients were divided into 2 groups: with and without diabetic retinopathy (DR+ and DR-). The DR+ group was characterized by a longer duration of diabetes, a shift of the lipid spectrum towards a higher atherogenicity, and a disproportion between serum level of malonic di aldehyde and SOD activity. No notable differences in the distribution of 7 alleles of CA T gene were noted. Division of patients into groups with different duration of NIDDM (more or less than 10 years) showed more pronounced differences between the DR+ and DRgroups. Maximal and significant differences in the metabolic (blood lipid spectrum) and genetic parameters (prevalence of a CAT gene allele) were observed between the DR+ subgroup with NIDDM duration of less than 10 years and the DRsubgroup with NIDDM longer than 10 years. Hence, consideration for diabetes duration as a factor of DR risk and use of the case-control "polar" clinical phenotype confirmed the contribution of oxidative stress to development of angiopathy and demonstrated the potentialities of CA Tgene polymorphous marker in studies of the genetic liability or resistance to disease depending on the balance between free radicals and antioxidant defense.
Combination of hormone replacement therapy with natural metabolite preparations (glycine and limontar) in the treatment of menopausal syndrome
Authors: Dreval A. V. , Marchenkova L. A. , Tshienin R. S. , Minchenko B. I. , Onoprienko G. A. , Shumsky V. I. , Komissarova I. A. , Narcissov Ya. R.
Published: October 2019

Clinical efficacy of two drugs, natural metabolites glycine and limontar, alone and in combination with substitute hormone therapy (SHT), is studied in patients with menopausal disorders. The clinical efficacy was assessed from the time course of neurovegetative, psychoemotional, and urogenital menopausal symptoms and from changes in mineral compactness of bone tissue and biochemical parameters of calcium-phosphorus metabolism and osseous metabolism.

The results confirmed the efficacy of SHT in all types of climacteric disorders (neurovegetative, psychoemotional, urogenital, and in postmenopausal osteopenia).

Combination of SHT with glycine and limontar did not affect the time course of the neurovegetative syndrome in general, but facilitated the arrest of arterial pressure differences and giddiness by estrogens. Moreover, glycine and limontar effectively relieve headaches.

Combination of glycine with limontar is effective in asthenoneurotic syndrome in general and in individual psychoemotional symptoms: irritability, labile spirits, sleep disorders. In general asthenia and urogenital disorders glycine and limontar accelerated the clinical effect of SHT and in case of low spirits and decreased libido extend the spectrum of positive effects of SHT. The combination of glycine with limontar had no positive effect on the mineral compactness of bones. Combination of both drugs with SHT attenuated the process of bone formation, increased calcium excretion with the urine, and increased the hypocalcemic effect, and hence, they should not be prescribed in postmenopausal osteopenia or osteoporosis.
Problems and prospects of development of neuroimmunoendocrinology
Authors: Akmaev I. G.
Published: October 2019

The last two decades of the outgoing century were marked by the birth and rapid development of a new field of knowledge neuroimmunoendocrinology. Before talking about its problems and development prospects, we will consider the prerequisites for the formation of this branch of endocrinology in our center.
Developing A Virtual Reality Application of Pathok Negoro Mosque for Digital Conservation
Authors: Setyawati Endang , Asyifa Adwiyah , Putro Hendro Trieddiantoro , Ischak Mohammad
Published: October 2019

In the last decades, new technologies have been developed and used for digital conservation. Nowadays, virtual reality is becoming an instrument applicable to many areas of science and visual communication. Pathok Negoro Mosque is one of the Javanese Islamic mosque buildings that was built in the 1700s. The building of this mosque still exists. Pathok Negoro Mosque several times has changed the shape and architecture of the building. The mosque was established during the reign of Sultan Hamengku Buwana I, has an extraordinary concept and philosophy. This project was an archiving physical space so they can be digitally preserved. In this paper, we will present the process of the VR app making also describe the benefits and challenges associated with this approach. The method was by research and development by prototyping the building in 3D model, then providing virtual tours in different place and times. This paper will discuss the VR issue focusing on several hardware devices and software platforms for digital content management. This case study allowing a better understanding of masjid pathok negoro history and atmosphere. The analyzed of virtual experience proved to be advantageous in delivering tangible and intangible information.
Analisis Proximate Briket Tempurung Kelapa dan Ampas Tebu
Authors: Setiani Vivin , Setiawan Adhi , Dhani Mey Rohma , Maulidya Risya Dwi
Published: October 2019

Fossil fuels are a non-renewable energy source and their existence will be depleted. An alternative is needed that can reduce fossil fuels by using biomass. Biomass waste in the form of bagasse and coconut shell can be used as an alternative fuel in the form of biobriquette. This study aims to analyze the quality value of briquettes from the proximate test of the composition of bagasse and coconut shell produced with briquette quality standards that refer to SNI 01-6235-2000 about wood charcoal briquettes. The variables in this study consisted of five variables. The variables in this study were mass ratio coconut shells to bagasse were 90%: 10%, 80%: 20%, 70%; 30%, 60%: 40% and 50%: 50% respectively. The results of the test of water content, ash content, and volatile matter of the best quality briquettes of five variables were 90% coconut shell and 10% bagasse.
Evaluating growth and biochemistry of Westiellopsis prolifica in response to Malathion
Authors: Dutta Jyotishmita , Baruah P P
Published: October 2019

The present endeavour was aimed to investigate the chronic response of Westiellopsis prolifica to an organophosphate insecticide malathion at different concentrations 30, 60 and 90ppm. The influence of malathion on growth (biomass), pigments (chlorophyll-a, carotenoid), release of metabolites such as protein and carbohydrate was analysed for a period of 16 days under aseptic laboratory conditions. Results revealed enhancement in chlorophyll-a production at 30ppm on 4th day (p?0.05) and 8th day (p?0.05), from the day of inoculation. On the other hand, there was a significant decrease in the carotenoid, protein and carbohydrate content with increase in malathion concentration in a time and dose dependent manner. However, a little but insignificant increase in biomass was recorded on the 4th day at 30ppm concentration over the control. The study revealed that the reduction in biomass, protein and carbohydrate content with the increase of malathion concentrations was an indication of its toxicity to the test cyanobacterium which is one of the natural biofertilizers in the rice field ecosystem.
3D-tiskani oralni dozirni oblici punjeni disperzijom ulja i djelatne tvari
Authors: Milićević Andrea , Gretić Matija , Matijašić Gordana
Published: October 2019

U ovom radu ispitana je mogućnost izrade oralnih dozirnih oblika tehnologijom 3D-tiska. Printani oblici podvrgnuti su in vitro ispitivanju oslobađanja djelatne tvari a rezultati su obrađeni u dodatku za Microsoft Excel, DDSolver. Proizvedeno je šest različitih čvrstih pripravaka. Rezultati ispitivanja oslobađanja djelatne tvari pokazali su profile oslobađanja s početnom vremenskom zadrškom, funkcijski povezanom s debljinom stijenke oblika. Profili su dobro opisani Peppas-Sahlinovim modelom. Pokazano je da tehnologija 3D-tiska ima potencijal postati metodom za jednostavnu i brzu izradu personaliziranih dozirnih oblika s odgođenim oslobađanjem.
Fitoremedijacija – pregled stanja i perspektiva
Authors: Milčić Nevena , Findrik Blažević Zvjezdana , Vuković Domanovac Marija
Published: October 2019

Remedijacija tala onečišćenih kompleksnim mješavinama organskih tvari i teških metala jedan je od najvećih izazova obnavljanja okoliša. Fitoremedijacija je naziv za skup postupaka koji upotrebljavaju biljke, njihove enzime i prisutne mikroorganizme iz zone korijenja za izolaciju, transport, detoksikaciju i mineralizaciju ksenobiotika, čime se smanjuje njihova koncentracija, pokretljivost ili toksični učinci. Fitoekstrakcija, fitostabilizacija, fitovolatizacija, fitorazgradnja i rizorazgradnja imaju velik potencijal za nedestruktivnu remedijaciju tala, što pokazuju brojna istraživanja u laboratorijskom mjerilu. Kako bi fitoremedijacija postala pouzdana tehnologija za širok spektar primjena u većem mjerilu, potrebno je ulagati resurse u nova istraživanja s ciljem boljeg razumijevanja procesa u cjelini, posebice na genetičkoj i biokemijskoj razini.
Nanofluidi kao medij za prijenos topline
Authors: Blažic Roko , Faraguna Fabio , Vidović Elvira , Jukić Ante
Published: October 2019

U posljednjih 20 godina nanofluidi su privukli pažnju znanstvene zajednice te se broj radova na temu nanofluida tijekom godina znatno povećao. Povećana toplinska vodljivost fluida uslijed dodatka nanočestica osnovno je svojstvo koje je potaknulo intenzivno istraživanje nanofluida. S obzirom na to da u industriji uvijek postoji težnja poboljšanju učinkovitosti proizvodnih procesa, pa tako i procesa hlađenja procesnih struja, povećana toplinska vodljivost rashladnih fluida otvara mogućnosti za postizanje navedenog cilja. U ovom radu dan je pregled metoda priprave nanofluida te opis parametara koji utječu na njihovu toplinsku vodljivost. Dan je i osvrt na modele kojima se opisuje toplinska vodljivost nanofluida te pregled mogućih mehanizama koji doprinose povećanju njihove toplinske vodljivosti.
PEDOPHILIA (DITINJAU DARI ASPEK PELAKU, KRIMINALITAS DAN PERLINDUNGAN ANAK)
Authors: Prasetyo Ratna Azis
Published: October 2019

Abstract. This article aims to explain the concept of pedophilia in terms of the perpetrators, criminality and child protection aspects. During this time children who are victims of pedophiliac suffer prolonged psychological injuries and even lead to death. Meanwhile, the legal settlement is not yet comparable to the injuries suffered by the victims and light punishment tends to make the sexual violence repeated. One of the light sentences for pedophiliacs is that the criminal law in this country has not specifically regulated criminal offenses and on the other hand, the concept of pedophilia is still considered as a mental disorder. Therefore, in handling it is not enough to rely on a legal approach, more than that the handling orientation needs to be directed at child protection. This is done by taking preventive measures such as fostering social sensitivity of the community, optimizing the role of social agents such as local social and institutional organizations and instilling early sex education in children.  Abstrak. Artikel ini bertujuan untuk menjelaskan konsep pedophilia ditinjau dari aspek pelaku, kriminalitas dan perlindungan anak. Selama ini anak-anak yang menjadi korban para pedophiliac mengalami luka psikologis berkepanjangan dan bahkan berujung kematian. Sementara itu, penyelesaian secara hukum dirasa belum sebanding dengan luka yang dialami korban dan hukuman yang ringan cenderung membuat tindakan kekerasan seksual tersebut terulang. Hukuman yang ringan bagi para pedophiliac ini salah satunya karena hukum pidana di negara ini belum mengatur secara khusus dalam delik pidana dan disisi lain, konsep pedophilia ini masih dianggap sebagai salah satu gangguan mental. Oleh sebab itu, dalam penanganannya tidak cukup dengan mengandalkan pendekatan hukum, lebih dari itu orientasi penanganan perlu diarahkan pada perlindungan anak. Caranya dengan melakukan upaya-upaya preventif seperti menumbuhkan kepekaan sosial masyarakat, mengoptimalkan peran agen-agen sosial seperti organisasi kemasyarakatan dan kelembagaan lokal dan menanamkan pendidikan seks usia dini pada anak-anak.
Landfill leachate sampling techniques
Authors: Cerne Olof , Junestedt Christian
Published: October 2019

A number of landfill Jeachates and related effluents has been characterised in researchprojects from 1996 till today. It has been important to carry out the sampling procedures witha minimum of contamination because many compounds are present at very lowconcentrations.
Laboratory tests of Estonian landfill leachate
Authors: Kängsepp Pille , Hogland William , Kriipsalu Mait , Timmusk Toomas
Published: October 2019

During the last decade, many laboratory, pilot and full-scale experiments have beenconducted to investigate the optimal low-tech purification methods for the treatment ofnumerous types of wastewaters. Constructed wetland is a low-tech treatment system, whichusually contains multiple treatment possibilities. Frequently, some kind of soil treatmentsystem is included as one treatment stage. Engineered wetland systems for purification ofwastewater and leachate are not yet widely spread in Estonia. The possibility to use peat asfilter media for treatment of leachate from Aardlapalu landfill (Tartu County, Estonia) hasbeen studied. The leachate was transported into the laboratory, aerated and percolated throughtwo different types of peat filters. The concentration of nitrogen compounds, COD and BODwas measured in the leachate before and after treatment. Hydrological consequences andchemical changes in the peat were investigated.
Dynamics Modeling of Nitrogen Compounds in Microalgae Cells. 2. Chemostat
Authors: Lelekov A.S. , Trenkenshu R.P.
Published: October 2019

The work focuses on dynamics modeling of nitrogen compounds in microalgae cells under chemostat conditions. The analysis of classical models (Michaelis-Menten, Monod, Droop),
which describe the kinetics of substrate-dependent growth of microalgae, was carried out. Classical models are shown to be applicable provided that the physicochemical parameters
of the medium such as temperature, cell irradiation, etc are constant. As an alternative approach, the possibility of using linear splines in kinetics modeling of nitrate absorption
by microalgae is shown. For the conditions of the chemostat, particular solutions for the generalized model of the dynamics of nitrogen compounds in the cells of microalgae
considered in the first part of the work were obtained, and boundary conditions for the culture growth at unlimited nitrogen were determined. For limited growth, the equation
for both the dependence of the specific growth rate on the intracellular nitrogen content, which coincides in form with the Droop model and the dependence of the specific
growth rate on the extracellular concentration of nitrogen, which coincides in form with the Monod model were obtained. The species-specific coefficients of the equations
such as the maximum specific rate of nitrogen absorption, the maximum specific rate of synthesis of structural components, the maximum content of reserve forms of nitrogen,
the minimum share of structural forms of nitrogen in the total cell content were determined.
Lateralization Profile in ASD Children with Different Speech Development Levels
Authors: Nemzer E. , Borodina L.G.
Published: October 2019

The lateralization profile and its link to speech development in 10 children with autism spectrum disorders and 20 neurotypical controls aged 6-7 were studied. Neuropsychological methods for the dominant arm, dominant ear, and dominant eye determination were used as well as for expressive and impressive speech assessment. Ambilateral results were found more often in autism spectrum disorders children compared to neurotypical controls. autism spectrum disorders children with ambilateral rates prevalence have shown higher results in speech development. There were more left ear dominance cases among autism spectrum disorders children compared with controls.
Syntax Transformations in Speech Therapy Work on the Development of Phrasal Speech in Students with ASD
Authors: Andreeva S.V.
Published: October 2019

The development of phrase speech is the most difficult area in speech therapy work with “speechless” schoolchildren with autism. The article describes speech therapy techniques for the development of syntax operations in schoolchildren with autism spectrum disorders and mild intellectual disabilities. Presented author’s speech therapy program for the development of arbitrary phrase speech in children with autism spectrum disorders combined with mild intellectual disability, based on the teachings of Noam Chomsky on grammatical transformations. The approbation of the speech therapy program was carried out by the author on the platform of the Federal Resource Center for the Organization of Comprehensive Support for Children with Autism Spectrum Disorders in the period from 2016 to the present.
Cognitive Process Development in Primary School age Children with Different Types of Ontogenesis.
Authors: Maksimenko M.Y. , Shal L.
Published: October 2019

As a result of the correctional work held, there is a need in evaluation of the dynamic state of various components of mental activity, namely: programming and control functions corresponding to the states of individual higher mental functions (motor, perceptions, spatial processes, speech, etc.), the pace of individual types of activity and volume sustainable performance, as well as features of communication skills. It is preferable to use types of tasks similar to those worked out in the system of the correctional-developing approach for objectification of dynamic changes results. The performance indicators of the correctional course are qualitative and quantitative changes identified in the proposed control tasks. Tasks, selected as control, reflect the level of development or deficiency of mechanisms, ensuring functioning of individual higher mental functions. The priority is given to the qualitative indicators of completed tasks in relation to specific indicators, whereas the quantitative – pace indicators provide information on the degree of stability, the automation of the requisite types of activities with age taking into account. Maximum attention should be paid to the dynamics of the "weak" links of higher mental functions.
Course of Correction. Part 4. Ending
Continuity of Inclusive Education and Psychological and Pedagogical Support for Persons with Special Educational Needs
Authors: Rubtsov V.V. , Alekhina S.V. , Khaustov A.V.
Published: October 2019

In the article the authors set a goal setting for the current consideration of the prerequisites of lifelong education and psychological and pedagogical support for people with special educational needs, the content of the concept of continuing education is determined. Presented are data from studies examining the attendance of educational institutions for children with disabilities, as well as information reflecting the intentions of parents to continue their education for children under 15 years of age, information about people with disabilities studying in vocational educational programs that emphasize the relevance of the continuing education of persons with disabilities, reflect a low the degree of readiness of parents to continue their education with children with disabilities, the need to build a system of continuous support I have children, adolescents and adults with disabilities in all regions of Russia, forming the basis for the continuity of personal educational path, the importance of developing a scientific approach to its study. Specific conditions for building a tracking model are defined. The experience of research and organization of continuous support of individuals with autism spectrum disorders is considered. It is concluded that it is necessary to discuss the topics of psychological and pedagogical support at the stage of obtaining a profession and employment. The value of unique practices in building an individual educational trajectory is noted.
AVALIAÇÃO DA ARBORIZAÇÃO DE ACOMPANHAMENTO VIÁRIO NA REGIÃO CENTRAL DE MARINGÁ (PR)
Authors: Albertin Ricardo Massulo , Silva Frederico Fonseca , Angeoletto Fábio Henrique Soares , Vieira Juliane Vier , De Angelis Bruno Luiz Domingos
Published: October 2019

A arborização de acompanhamento viário faz parte da infraestrutura urbana e deve ser planejada e gerida em conjunto com os demais componentes urbanos, como forma de garantir níveis satisfatórios de qualidade de vida para a população. Neste contexto, o presente trabalho teve por objetivo avaliar a arborização de acompanhamento viário na Zona de Comércio Central (ZCC) da cidade de Maringá, Paraná, Brasil. Para isso, realizou-se levantamento censo quali-quantitativo no qual se identificou as árvores por meio da metodologia usual taxonômica e consulta bibliográfica, e avaliou-se as características do local de plantio, sistema radicular, copa e poda. Os resultados indicaram a presença de 1.758 exemplares arbóreos de 57 espécies, com predominância de sibipirunas (36,6%) tipuanas (20,4%) e alecrim de Campinas (15,8%). Em relação ao local de plantio, 33,2% das árvores estão plantadas no meio do lote. A avaliação do sistema radicular demonstrou que 30,0% das árvores provocam rachaduras nas calçadas. Verificou-se que 20,0% das copas estão interferindo de forma negativa nas edificações. Os dados referentes às podas demonstraram que 19,0% são de árvores em que não há indícios de poda. Conclui-se que a riqueza de espécies vegetais na área de estudo é correntemente alta, porém mal distribuída. Nota-se que em zonas comerciais há uma maior ocorrência de impactos negativos das copas sobre as edificações.
UM ESTUDO SOBRE A RACIONALIDADE NAS ORGANIZAÇÕES DE EXTENSÃO RURAL: O CASO DA EMATER
Authors: Rossés Gustavo Fontinelli , Souza Renato Santos de
Published: October 2019

A partir de uma análise histórica, tem-se observado grande preocupação com questões que envolvem a assistência técnica e a extensão rural e sua importância enquanto agente promotor do acesso às novas tecnologias e ao conhecimento. Nesse cenário, emergem os serviços de assistência técnica e extensão rural, que inicialmente contavam com ações prioritariamente governamentais. Inúmeras discussões e postulações emergiram no sentido de dar maior significado e compreensão da racionalidade organizacional e suas implicações para a ação extensionista. Diante disso, este estudo tem como objetivo analisar a racionalidade empregada em organizações de extensão rural, bem como os efeitos sobre a ação extensionista. Em termos metodológicos esse estudo foi caracterizado como sendo qualitativo. Fundamentado em um estudo de caso, realizado na EMATER, esse trabalho valeu-se da coleta de dados por meio de 09 entrevistas, análise documental e observação direta, sendo delineados a partir de um conjunto detalhado de categorias de análise. Em termos de análise dos resultados adotaram-se as técnicas de classificação, categorização e, essencialmente, a análise de conteúdo. Os resultados permitiram concluir que a EMATER opera, prioritariamente, com base nos pressupostos de uma racionalidade formal. Também foi possível concluir que as políticas públicas de assistência técnica e extensão rural têm influenciado consideravelmente o comportamento da EMATER, tanto do ponto de vista de sua concepção, como de sua implementação.
ANÁLISE DA ESTABILIDADE DE CIANETO LIVRE EM MANIPUEIRA PARA UTILIZAÇÃO EM MANEJOS FITOSSANITÁRIOS DE PRAGAS E DOENÇAS
Authors: Camara Guilherme de Resende , Alves Fábio Ramos , Moraes Willian Bucker
Published: October 2019

A manipueira, resíduo líquido extraído da mandioca (Manihot esculenta L.) durante o processo de fabricação de farinha e (ou) amido, apresenta um glicosídeo tóxico denominado linamarina, do qual se origina o ácido cianídrico (HCN). As características químicas e orgânicas da manipueira possibilitam a sua utilização no manejo fitossanitário de plantas agrícolas, objetivando reduzir as populações de patógenos a níveis inferiores aqueles capazes de causar perdas. No entanto, apesar do avanço nas pesquisas, pouco se conhece a respeito da estabilidade do ácido cianídrico na manipueira após sua extração. Objetivou-se com o presente estudo avaliar a estabilidade e permanência do ácido cianídrico (HCN) na composição da manipueira, visando auxiliar pesquisadores e produtores no uso mais eficiente e racional deste resíduo. Conclui-se que a manipueira apresenta variável estabilidade e contínua permanência do ácido cianídrico (HCN) em sua composição, dentro do período avaliado, independente da forma de armazenamento.
A CULTURA DA CANA-DE-AÇÚCAR (Saccharum officinarum) E O MANEJO DA IRRIGAÇÃO
Authors: Lopes Sobrinho Oswaldo Palma , Silva Gerlange Soares da , Pereira Álvaro Itaúna Schalcher , Sousa Aline Bezerra de , Castro Júnior Wady Lima , Santos Leonardo Nazário Silva dos
Published: October 2019

Tendo em vista a grande competição pelo uso da água, nos próximos anos possivelmente haverá uma mudança no paradigma do manejo da irrigação, visando uma maior eficiência econômica do que a exigência de água pelas plantas. Desta forma, considerando a importância econômica que a cultura de cana-de-açúcar tem no Brasil e no mundo, associada à produção de açúcar, energia e álcool, a presente revisão busca apresentar um estudo sobre as técnicas de otimização no manejo da irrigação para a cana-de-açúcar por ser uma cultura em que o déficit hídrico é um dos fatores que afeta a produtividade. O foco principal proposto foi analisar os resultados científicos sobre a resposta da cana-de-açúcar ao déficit hídrico e a eficiência de uso da água, com as perspectivas socioeconômicas do setor canavieiro. Por meio de análise de dados secundários disponíveis na literatura relacionados ao tema, tanto o rendimento quanto a produção de açúcar e de etanol da cana-de-açúcar irrigada são dependentes da quantidade de água que é aplicada, do manejo da irrigação em combinação com a quantidade correta de adubação, da variedade, da idade do corte, do tipo de solo e do clima. Portanto, o sistema de irrigação para a cultura da cana-de-açúcar mais recomendado é o gotejamento, pois aumenta a produtividade, reduz os tratos culturais e eleva a longevidade dos canaviais.
Knowledge, attitude and practice of parents regarding antibiotic use in children
Authors: Shamshu Rasheena , Sudhir Shyam , Nuwera Haleema
Published: October 2019

Background: Antibiotic resistance has become an emerging issue worldwide due to the rampant and excessive use of antibiotics for any and every condition. At present, antibiotics are the most commonly sold drugs in the developing countries which have been the cause for escalation of antibiotic resistance. Lack of knowledge, awareness and practice among parents regarding antibiotics use is the most important cause for antibiotic misuse.Methods: Cross sectional hospital based questionnaire study conducted among 200 parents of children attending the outpatient or inpatient department at Yenepoya Medical College Hospital, Mangalore; using personal interview method. Parents were asked to answer the statements on a 5-point Likert scale (“strongly agree”, “agree”, “uncertain”, “disagree”, “strongly disagree” or “never”, “sometimes”, “often”, “most of the time”, “always”). Statistical Package of social science (SPSS) software was used for analysis of data.Results: Out of the 200 parent’s majority of the respondents (69%) were mothers. There was very little difference in percentage of respondents that disagreed with notion that antibiotics must be administered in any case of fever (43.3%). 42.3% mentioned that antibiotics were always necessary in ARI. Most common symptoms to visit pediatrician included cough (23.4%), followed by ear pain (18.1%) and nasal discharge (12.9%). 17.5% of parents never questioned the pediatricians if antibiotic administration was necessary and more than 2/3rd of the parents declared that pediatricians provided sufficient information regarding diagnosis and therapy.Conclusions: Majority of parents admitted to self-administration of antibiotics. There is a need of intervention to increase awareness regarding judicious use of antibiotics and to check un-prescribed dispensing of antibiotics. Strategies for effective communication with patients and prudent prescription of antibiotics should be included in physician education to ensure patients’ adherence to advice and consequently to reduce self-medication with antibiotics.
A cross sectional study to find incidence of clinically detectable congenital malformations and factors affecting it in tertiary care hospital
Authors: Yaragatti Vikram V. , . Shivanagouda
Published: October 2019

Background: Congenital malformations are emerging as an important perinatal problem, contributing sizably to the perinatal mortality with considerable repercussions on the mothers and the families. Patients with multiple congenital anomalies present a relatively infrequent but tremendously difficult challenge to the pediatrician. Authors objective was to study the incidence of clinically detectable congenital malformations among consecutive births in hospital deliveries examined during hospital stay.Methods: A prospective cross sectional study was conducted in Department of Pediatrics at Dr R N Cooper Municipal General Hospital, Mumbai from June 2016 to June 2017. All live births from June 2016 to June 2017 were considered in the studyResults: The total number of deliveries in our hospital were 3120(100%) and the total number of babies with congenital anomaly were 43(1.4%), So the incidence of congenital anomalies amongst study population was 1.4%. The involvement of various systems was seen in our study. The involvement of CNS (9.3%), Eye (7%), ENT (28%), GIT (20.9%), Urinary Tract (2.3%), Musculoskeletal System (35%), Gentialia (7%), CVS (7%).Conclusions: Congenital malformation, one of the important causes of infant mortality and morbidity can be reduced by proper preconception care and level two anomaly scan. Congenital anomalies must be identified, as early diagnosis and surgical correction of malformed babies offer the best chance for survival.
Prevalence of impaired fasting glucose in different grades of obesity
Authors: Rai Jitendra Kumar , Wadhwani J. L. , Sharma Manuj , Dubey T. N.
Published: October 2019

Background: Impaired fasting glucose (IFG) is a pre-stage to type 2 diabetes mellitus (T2DM) in adults and generally in obese population. In different studies this occurrence varied significantly, but the true prevalence is unknown due to lack of larger representative cohort studies. Authors objectives was to study the prevalence of IFG in different grades of obesity.Methods: One hundred obese subjects of obesity Grade1 (BMI >25 kg/m2 but <30) and Grade 2 (BMI >30 kg/m2) were studied at Gandhi Medical College, Bhopal from April 2019 to June 2019. Physical examination, blood investigations including fasting blood glucose and oral glucose tolerance test (OGTT) was carried out for all the patients.Results: Out of 100 subjects, 18(9%) males and 18(9%) females had IFG. Among male subjects highest IFG was recorded in the age group of 60+ years and in the weight rage of 71 to 80 kg. In female subjects, highest prevalence was in the age group 51 to 60 years and in weight range of 51-60 kg. Out of 24 males and 34 female of with Grade 1 obesity, 7% and 10.4% had IFG similarly, out of 25 males and 17 females with grade 2 obesity, 11% and 7.6% had IFG.Conclusions: IFG is highly prevalent in different grades of obesity. Obesity is the risk factor for the development of diabetes.
Study of electronystagmography in the diagnosis and efficacy of follow-up after treatment, in patients with vertigo of peripheral origin
Authors: . Zorengpuii , Khiangte Lalnuntluangi , P. Naveen
Published: October 2019

Background: Vertigo is a symptom of multisystemic disorders of various etiological factors with different clinical manifestations. The disorders causing the symptom may be of peripheral or central origin, and accurate diagnosis of the underlying pathology is warranted for effective treatment. Balance is a complex sensorimotor task involving accurate and redundant sensory input from the visual, vestibular and proprioceptive systems, central nervous system integration of the sensory signals and the generation of the appropriate motor commands and adequate musculoskeletal capabilities to perform the motor tasks involved in occulomotor and posture control.

Methods: The study was conducted in the Department of Otorhinolaryngology, Regional Institute of Medical Sciences, Imphal, Manipur. 50 cases presenting with symptoms of vertigo were studied irrespective of age, sex and duration of illness in order to find out the cause of peripheral vertigo by using different diagnostic parameters with main emphasis on electronystagmography. All patients underwent pure tone audiometry for audiology assessment. The cases were treated and followed-up to a minimum period of 3 months, electronystagmography repeated during each visit to evaluate the efficacy and response to treatment.  

Results: Vertigo of peripheral origin comprised of 64%. Meniere’s disease was the largest group (28%) amongst the causes of peripheral vertigo. Subjective improvement of vertigo and electronystagmography was observed in all patients after treatment.

Conclusions: Vertigo was most common in fourth decade of life and males have a slight predominance. Medical management was the mainstay of treatment. Patients with peripheral vertigo responded well to symptomatic and supportive treatment. Electronystagmography facilitates diagnosis of vertigo.
Lobular capillary hemangioma of the nasal cavity treated by radiofrequency excision: a retrospective study
Authors: Garag Santosh , Jalisatgi Roshan R. , Jinka Satyanarayan Arunkumar , Naik Ashok S. , Shetty Sushan
Published: October 2019

Background: The objective of the study was to assess the clinical presentation, radiological features and treatment by radiofrequency excision of lobular capillary hemangioma of the nasal cavity in a tertiary care hospital.

Methods: A retrospective descriptive study of capillary hemangioma of the nasal cavity on patients attending a tertiary care hospital from January 2015 to January 2019 was conducted. Case records were analysed and results were tabulated.  

Results: There were 14 patients of capillary hemangioma of the nasal cavity of which 11 were males and 3 females with age ranging from 15 to 68 years. Epistaxis was the most common symptom followed by nasal obstruction. Anterior nasal septum was the most commonly affected area followed by posterior nasal septum, nasal vestibule and inferior turbinate. CT scans showed enhancing lesion with no bony erosion. Patients underwent endoscopic and classical excision by radiofrequency. No patient had any recurrence over 6 to 24 months follow-up.

Conclusions: Lobular capillary hemangiomas of the nasal cavity present with epistaxis as the common symptom and occur most commonly over anterior part of nasal septum. Excision by radiofrequency results in minimal complications without any recurrence.

 
Прогнозирование объемов инвестиций населения в жилищное строительство в республике Беларусь
Authors: Еременко Марина Михайловна
Published: October 2019

Статья посвящена актуальной проблеме регионального развития – разработке методического инструментария, с помощью которого можно прогнозировать объемы инвестиций населения в строительство жилых домов. Методика была построена на основе логико-аналитических методов, а также многофакторного корреляционно-регрессионного анализа. Разработка указанной методики включила три основных блока. Первый блок предполагает составление максимально широкого перечня экономических факторов, определяющих величину результирующего признака. Во втором блоке осуществлен отбор факторов из имеющегося перечня и построена экономико-математическая модель. В третьем блоке проведена оценка точности модели. Апробация методического инструментария проведена на примере Республики Беларусь, для которой была разработана модель и составлен прогноз. В модель были отобраны такие факторы как доступность строительства жилья в виде отношения номинальной начисленной среднемесячной заработной платы к стоимости строительства 1 кв.м. жилья и денежные доходы в расчете на душу населения. Прогнозный показатель по полученной модели был посчитан по трем различным сценариям: на основе показателей социально-экономического развития Республики Беларусь, определенных согласно программным правительственным документам Республики Беларусь на текущую пятилетку, по трендам на три периода вперед, а также в соответствии с пессимистическим прогнозом на указанный период. Полученная модель позволила рассчитать, что увеличение денежных доходов в расчете на душу населения на 1 руб. ведет к увеличению объемов инвестиций населения в основной капитал на строительство жилых домов на 5 млн. руб. Прогноз объемов инвестиций населения в основной капитал на строительство жилых домов может быть полезен застройщикам жилых домов, производителям строительных материалов, республиканским органам государственного управления, иным заинтересованным организациям и гражданам.
К вопросу воспроизводства жилищной недвижимости на основе рециклинга отходов строительной отрасли
Authors: Крыгина Алевтина Михайловна , Крыгина Наталья Михайловна
Published: October 2019

В статье приведены результаты исследования использования стратегий инновационного развития энерго-, ресурсоэффективной жилищной недвижимости на основе технологий рециклинга отходов стройиндустрии. Проанализированы основные проблемные аспекты воспроизводства жилищной недвижимости, широкий спектр проблемных вопросов, обусловленных россом объемов отходов промышленности, в том числе по виду деятельности «Строительство». Предложена модель устойчивости системы «объект-среда обитания» на основе синергетической инновационной стратегии развития энергоэффективных объектов эко-недвижимости с использованием рециклинга отходов строительной промышленности. Статья имеет практическое значение для исследователей в области устойчивого развития жилищной недвижимости, аспирантов, магистров.
Опыт Швеции по экологизации системы городского центрального теплоснабжения на примере ТЭЦ «Вяртаверкет»
Authors: Зимаков Андрей Владимирович
Published: October 2019

Статья посвящена исследованию положительного опыта Швеции по развертыванию и экологизации системы центрального теплоснабжения на примере Стокгольма и ТЭЦ «Вяртаверкет». Последовательный перевод системы теплоснабжения на использование возобновляемых источников энергии привел к значительному улучшению городских экологических показателей. Существенную роль сыграло использование тепловых насосов, применяемых не только для нужд теплоснабжения, но и охлаждения. В статье анализируется опыт развертывания системы централизованного охлаждения, а также интеграции систем охлаждения и теплоснабжения в единый производственный комплекс. Особое внимание уделено опыту интеграции распределенных независимых поставщиков тепла в систему центрального теплоснабжения города, что позволяет утилизировать энергию сбросного низкопотенциального тепла. Данный опыт может быть использован государственными и муниципальными органами при разработке стратегии развития и экологизации системы городского теплоснабжения, а также перспективных инвестиционных проектов, направленных на повышение качества коммунальных услуг.
Основные факторы, определяющие стоимость земельного участка под индивидуальное жилищное строительство (на примере г. Казань)
Authors: Боровских Ольга Николаевна
Published: October 2019

Строительство или покупка индивидуального жилого дома за городом, характеризующегося более современным, комфортным и желанным уровнем жизни, является целью для многих семей. В соответствии с этим, вокруг крупных городов появляются большие и маленькие коттеджные поселки, которые предлагают современную инфраструктуру, охраняемую территорию и прочие удобства. В рамках исследования было проанализировано порядка 50 коттеджных поселков эконом и бизнес-класса вокруг города Казани, что позволило составить наиболее полную картину событий, сложившуюся в данном сегменте жилой недвижимости. Коттеджные поселки анализировались по таким характеристикам как местоположение, статус земли, количество, размер и стоимость земельных участков, наличие инженерных коммуникаций и социальной инфраструктуры, качество дорожного покрытия внутри поселка, качество обеспечения безопасности, экологические условия, этап реализации и застройщик (инвестор) проекта. В результате исследования было выявлено, что по-прежнему большинство коттеджных поселков реализуют земельные участки без подряда. Их доля составляет 85% от общего числа, что является отражением снижения покупательской способности населения на фоне кризисных явлений в экономике. Материалы статьи могут иметь практическую значимость для девелоперских компаний, а также для потенциальных покупателей земельных участков в коттеджных поселках Республики Татарстан.
Факторы и тренды развития российского рынка многоквартирного жилья по итогам 2017 года
Authors: Стерник Геннадий Моисеевич , Стерник Сергей Геннадьевич
Published: October 2019

В статье представлен анализ и прогноз развития российского рынка многоквартирного городского жилья по итогам 2017 года на основе разработанной авторами комплексной методологии, учитывающей макро- и микроэкономические, финансовые, институциональные и правовые факторы влияния. Указанная методология полностью изложена в монографии авторов, выпущенной в мае 2018 года, и основана на научных результатах, накопленных за 25 лет (с 1991 по 2016 г. включительно) мониторинга рынка и исследования закономерностей становления и развития рынка недвижимости в условиях перехода экономики России от плановой к рыночной, с учетом специфических особенностей законодательной среды, состава и структуры объекта исследования, институциональных особенностей регулирования и управления, изменения ожиданий и поведения субъектов рынка и населения.
В данной статье, помимо изложения основных положений указанной методологии, особое внимание уделено признакам, причинам и механизмам смены во многих российских городах и регионах состояния рынка от депрессии к оживлению, начиная с 2016 года, и даже с тенденцией к росту в 2017 году. Вместе с тем, рассмотрено и действие факторов, которые могут серьезно помешать указанному росту в горизонте 3-5 лет. В исследованную выборку входят 27 городов и один регион (Московская область, по которой приводятся усредненные по городам данные), в том числе 21 город, являющийся центрами субъектов РФ, с совокупной численностью населения более 43 млн чел.
Ten Years of Strategic Collaboration of Libraries in Digital Preservation
Authors: Zarnitz Monika , Bähr Thomas , Arning Ursula
Published: October 2019

The German National Specialist Libraries cooperate closely in the field of digital preservation. One of the partners hosts the preservation system, while each library creates its own workflows and is free to ingest its digital material into this system. This paper delineates the factors for success of this collaboration. It describes the different aspects of collaboration in digital preservation and describes the benefits and costs of cooperation in this field as a case study.

Digital preservation is resource intensive and the required technology is complex. Therefore the libraries benefit from synergy effects: Reduced cost by sharing the preservation system, usage of similar workflows and formats of digital objects, work sharing in networking activities and staff training. The paper also stresses the advantages and difficulties while applying for certificates in a consortium. Their collaboration extends to intensive national and international networking activities, which yield more contacts than a single library could maintain if it acted on its own. The libraries’ staffs are active in working groups of nestor – the German network for digital preservation – and in working groups of the Open Preservation Foundation.
Assessment of the core functions of hepatitis B surveillance system in the southeastern Iran: a qualitative study
Authors: Mahmoodi Mozhgan , Yazdanpanah Abbas , Ghavam Abbas , Sheikhzadeh Khodadad
Published: October 2019

Introduction: Viral hepatitis has been declared as one of the major health problems by World Health Organization. Hepatitis B surveillance system is one of the most important tools for managing the disease and achieving the targets of disease elimination. Despite its high efficiency, hepatitis B surveillance system has always been faced with many challenges. Therefore, the present study aimed to investigate the core functions of the hepatitis B surveillance system in southeastern region of Iran.
Method: Semi-structured in-depth interviews were conducted with 14 hepatitis B surveillance experts in five counties of Sistan and Baluchestan Province, southeast Iran. The data were analyzed using content analysis method, based on the structure of the disease surveillance system. Purposeful sampling method was carried out and continued until saturation of the themes was achieved.
Results: The main studied themes were case finding, case reporting, case registration, case confirmation, data analysis, sending feedback, and implementing interventions. The results of this study showed that all of the core functions of the hepatitis B surveillance system were running in the studied counties, although they did not meet the relevant standards in some cases.
Conclusion: It seemed that, despite the numerous efforts and activities, it was still far from reaching the targets of the program. Considering the goal of World Health Organization to eliminate hepatitis B by 2030, it is essential to address these challenges and make attempt to overcome them.