bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical significance of bone marrow edema in the late stages of osteoarthritis
Authors: Snigireva A. V. , Noskov S. M. , Maksimov M. L.
Published: January 2020

The use of magnetic resonance imaging (MRI) for osteoarthritis made it possible to simultaneously detail the state of cartilage, subchondral bone, menisci, ligaments, and synovial membrane. In some studies, a correlation was found between bone marrow edema (BME) and the intensity of the pain syndrome, the progression of OA and the risk of total knee replacement. In other studies, these data were not confirmed. It has been suggested that BME in OA, leading to debilitating pain, is not associated with trauma and is determined by an increase in extracellular fluid. Analysis of MRI images of 80 patients with 1-3 stages of knee osteoarthritis revealed a statistically significant relationship between the presence of bone marrow edema and the thickness of the cartilage of the femur and tibia, rupture and degradation of the medial menisci, the presence of Baker cysts and thickening of the synovial membrane. No reliable relationship was found with the presence and severity of synovitis. A review of data on the effect of various methods of conservative therapy on bone marrow edema in osteoarthritis is presented. The effect of anti-osteoporotic drugs, prostacyclin, Pentosan polysulfate sodium chondroitin sulfate is considered. Thus, OKM is of interest both in terms of the pathogenesis of OA and as an indicator of the effectiveness of the treatment of OA. Our data demonstrate a high incidence of OKM in the late stages of OA. The effect of pharmacological therapies on OKM requires further study.
Cardiac diabetic autonomic neuropathy
Authors: Akhmedzhanova L. T. , Belyakova T. A. , Podkovko Yu. A. , Shor Yu. M.
Published: January 2020

The prevalence of diabetes mellitus (DM) is steadily increasing and represents a significant public health problem. At the same time, the incidence of neurological complications of diabetes mellitus, especially diabetic polyneuropathy, is increasing. Cardiac autonomic neuropathy, a form of diabetic polyneuropathy, is the most serious complication of diabetes mellitus, as it is an independent risk factor for cardiovascular complications in patients with diabetes mellitus and is associated with increased mortality. Due to prolonged asymptomatic flow, cardiac autonomic neuropathy is often diagnosed at a late stage when treatment is not very effective. A targeted search for clinical symptoms of the disease and especially the conduct of cardiovascular tests, which make it possible to diagnose the pathology at an early stage, is essential. Clinical manifestations of cardiac autonomic neuropathy, methods of clinical and instrumental diagnostics, treatment of the disease are considered in detail in the article. The clinical case of a patient with type 2 diabetes mellitus and cardiac autonomic neuropathy, represented by orthostatic hypotension, which is the most disabling symptom, is considered. On the example of a clinical case the medicamentous and non-medicamentous approaches to treatment are discussed, as well as the role of antioxidant therapy, in particular, the preparation of alpha-lipoic acid («Berlithion») in the treatment of cardiac autonomic neuropathy.
Henri Fayol ve Yönetim Alanına Katkıları Üzerine Bir İnceleme
Authors: Karaboğa Tuğba , Zehir Cemal
Published: January 2020

Bu çalışmada Henri Fayol’un 20. yüzyılın başlarında yayımlamış olduğu “Genel ve Endüstriyel Yönetim” adlı kitabından hareketle Fayol’un hayatı, yönetim bilimine katkıları, ortaya çıkardığı Yönetim Süreci Yaklaşımının özellikleri, Taylor ve Mintzberg ile karşılaştırılması, yönetime deneysel yaklaşımı ve modern yönetim tekniklerinin oluşmasına katkılarına yer verilmiştir. Yönetim Süreci Yaklaşımının fikir babası olarak kabul edilen Fayol’un hayatı, yaşam tarzı, aldığı eğitimlerin ve yaşadığı dönemin kuşkusuz yönetim alanında çığır açan bulguları üzerinde önemli katkıları bulunmaktadır. Bu çalışmada Fayol’un yönetim alanına katkılarının yanı sıra yönetimle ilgili ortaya attığı fikirlerin ve ilkelerin modern yönetime katkıları da farklı bakış açılarından ele alınmıştır. Fayol’u herkes gibi önyargılarla ve genel kanılarla eleştirmek yerine modern teorisyenlerin yaklaşımlarıyla karşılaştırmalar yapılarak bu yaklaşımların ortaya çıkmasına öncülük eden fikirleri ve Fayol’un yaklaşımlarının çağdaş yönetimdeki karşılığı açığa çıkarılmaya çalışılmıştır. Dolayısıyla araştırmacılara ve uygulamacılara modern yönetim yaklaşımlarını Fayol’un önderliğinde daha zengin bir bakış açısıyla analiz etme fırsatı sunmak amaçlanmıştır. Bu bağlamda kapsamlı bir literatür taraması yapılarak çalışma sonucu bulunan bulgular makale içerisinde çeşitli başlıklarda sunulmuştur.
Web-based Tools for Drug Repurposing: Successful Examples of Collaborative Research
Authors: Vanhaelen Quentin
Published: January 2020

Computational approaches have been proven to be complementary tools of interest in identifying
potential candidates for drug repurposing. However, although the methods developed so far
offer interesting opportunities and could contribute to solving issues faced by the pharmaceutical
sector, they also come with their constraints. Indeed, specific challenges ranging from data access,
standardization and integration to the implementation of reliable and coherent validation methods
must be addressed to allow systematic use at a larger scale. In this mini-review, we cover computational
tools recently developed for addressing some of these challenges. This includes specific databases
providing accessibility to a large set of curated data with standardized annotations, web-based
tools integrating flexible user interfaces to perform fast computational repurposing experiments and
standardized datasets specifically annotated and balanced for validating new computational drug repurposing
methods. Interestingly, these new databases combined with the increasing number of information
about the outcomes of drug repurposing studies can be used to perform a meta-analysis to
identify key properties associated with successful drug repurposing cases. This information could
further be used to design estimation methods to compute a priori assessment of the repurposing possibilities.
Recent Development of 1,2,4-triazole-containing Compounds as Anticancer Agents
Authors: Wen Xiaoyue , Zhou Yongqin , Zeng Junhao , Liu Xinyue
Published: January 2020

1,2,4-Triazole derivatives possess promising in vitro and in vivo anticancer activity, and many anticancer agents such as fluconazole, tebuconazole, triadimefon, and ribavirin bear a 1,2,4-triazole moiety, revealing their potential in the development of novel anticancer agents. This review emphasizes the recent advances in 1,2,4-triazole-containing compounds with anticancer potential, and the structureactivity relationships as well as mechanisms of action are also discussed.
Importance of Pharmacist in Oxaliplatin Hepatotoxicity Associated with Inadequate Nutritional Diet: Case Report
Authors: Cavalcanti Iago D.L. , Costa Diogo T. , de Aguiar Silva Andreza T. , Peres Adrya L. , de Oliveira Coimbra Cynthia G.
Published: January 2020

A 40 years old male with colorectal cancer, with an unbalanced hypercaloric diet, attempted, on his own initiative, to gain weight, without nutritional follow-up, during chemotherapy treatment with oxaliplatin protocols, without pharmaceutical guidance. When initiating the new protocol, with oxaliplatin/irinotecan combination therapy, he presented symptomatology suggestive of hepatic injury during the administration of oxaliplatin. When performing a Magnetic Resonance Imaging of the total abdomen, hepatic nodules were identified indicating lesions resulting from the chemotherapy treatment, and blood tests indicated Aspartate aminotransferase levels in 55 U/L and Alanine aminotransferase in 68 U/L. The patient underwent partial hepatectomy for the removal of the nodules and was currently in clinical care, presenting a frame stable but non-therapeutic possibility. This case highlights the importance of interaction among health professionals, reinforcing the need for multiprofessional approaches to better patient response to antineoplastic treatment.
The Effect of Prostate Cancer Radiotherapy on Testosterone Level: A Systematic Review and Meta-analysis
Authors: Mortezaee Keywan , Motallebzadeh Elham , Milajerdi Alireza , Farhood Bagher , Najafi Masoud , Sahebkar Amirhossein
Published: January 2020

Introduction:

In the current study, a systematic search and meta-analysis were performed to evaluate the effect of prostate cancer radiotherapy on testosterone levels of patients.

Methods:

To illuminate the effect of radiotherapy on the testosterone level of prostate cancer patients, a systematic search was conducted in accordance with the PRISMA guideline in electronic databases of Scopus, Embase, PubMed, Web of Science, and clinical trials up to December 2018 using relevant keywords. Based on a certain set of inclusion and exclusion criteria, 12 eligible studies that had data on the testosterone level following prostate cancer radiotherapy were included in the meta-analysis.

Results:

According to the various techniques of prostate cancer radiotherapy, the dose values scattered to the testicular tissues ranged from 0.31 to 10 Gy. Combining the findings from 12 studies, it was found that prostate cancer radiotherapy leads to a significant reduction in the testosterone level (Weighted Mean Difference [WMD]: -51.38 ng/dL, 95% CI: -75.86, -26.90, I2=0.0%, P<0.05). Furthermore, subgroup analysis by the patient number showed a significant reduction in the testosterone level at patient number < 50 (WMD: -80.32 ng/dL, 95% CI: -125.10, -35.55, I2= 0.0%) and 50 < patient number < 100 (WMD: -46.99 ng/dL, 95% CI: - 87.15, -6.82, I2= 0.0%). Subgroup analysis based on treatment technique type revealed a significant reduction in testosterone level after conventional radiotherapy (WMD: -56.67, 95% CI: -100.45,-12.88, I2= 34.3%) and IMRT/SBRT technique (WMD: -57.42, 95% CI: -99.39, -15.46, I2= 0.0%) in comparison with the proton therapy (WMD: 0.00, 95% CI: -80.24, 80.24).

Conclusion:

The findings showed a significant decrease in the testosterone level of prostate cancer patients after radiotherapy compared with pre-treatment levels.
Ocular Manifestations in Late Onset Behçet’s Disease
Authors: Saadouli Dorsaf , Mansour Khaoula Ben , Yahyaoui Salem , Afrit Naouel El , Lahmar Amel , Afrit Ali El
Published: January 2020

Background:

Behçet’s disease is frequent in Tunisia and potentially serious, which can
endanger both the vital and visual prognosis. Late occurrence of the disease is uncommon and less
frequently investigated.

Aims:

The aim of this study was to analyse the demographic characteristics and ocular manifestations
of patients with late-onset Behçet disease in Tunisia, North Africa.

Methods:

A retrospective study was performed on 38 eyes of 21 oculo-Behçet patients over a seven-
year period.

Results:

The mean age of our patients was 54.81 years. The sex ratio M/F was 2.5. The period between
the onset of the first symptom and diagnosis of Behçet’s disease varied from 3 days to 2
years. The primary complaint was a decrease in visual acuity, reported in 8 patients. Ocular involvement
revealed Behçet’s disease in 2 patients, bilateral in 17 patients, and active in 31 eyes.
The ocular manifestations in late-onset Behçet’s disease were dominated by uveal involvement (30
eyes). The most frequent form of uveitis was panuveitis noted in 13 eyes. Ocular complications
were dominated by macular involvement in 8 patients (14 eyes). Blindness was noted in 4 eyes of 4
patients (10.5%). Topical corticosteroids were used in 30 eyes. Three patients were treated only
with oral corticosteroid and 9 patients with a combination of oral corticosteroid and immunosuppressive
agents.

Conclusion:

Since the course of the ocular involvement in late-onset Behçet’s disease is regarded
to be relatively mild, it is noteworthy that our study revealed that blindness was noted in 10,5% and
posterior uveitis and panuveitis were the most common uveal lesion.
Exploitation of Outgoing and Incoming Telephone Calls in the Context of Circadian Rhythms of Social Activity Among Elderly People: Observational Descriptive Study
Authors: Aubourg Timothée , Demongeot Jacques , Provost Hervé , Vuillerme Nicolas
Published: January 2020

Background

In the elderly population, analysis of the circadian rhythms of social activity may help in supervising homebound disabled and chronically ill populations. Circadian rhythms are monitored over time to determine, for example, the stability of the organization of daily social activity rhythms and the occurrence of particular desynchronizations in the way older adults act and react socially during the day. Recently, analysis of telephone call detail records has led to the possibility of determining circadian rhythms of social activity in an objective unobtrusive way for young patients from their outgoing telephone calls. At this stage, however, the analysis of incoming call rhythms and the comparison of their organization with respect to outgoing calls remains to be performed in underinvestigated populations (in particular, older populations).

Objective

This study investigated the persistence and synchronization of circadian rhythms in telephone communication by older adults.

Methods

The study used a longitudinal 12-month data set combining call detail records and questionnaire data from 26 volunteers aged 70 years or more to determine the existence of persistent and synchronized circadian rhythms in their telephone communications. The study worked with the following four specific telecommunication parameters: (1) recipient of the telephone call (alter), (2) time at which the call began, (3) duration of the call, and (4) direction of the call. We focused on the following two issues: (1) the existence of persistent circadian rhythms of outgoing and incoming telephone calls in the older population and (2) synchronization with circadian rhythms in the way the older population places and responds to telephone calls.

Results

The results showed that older adults have their own specific circadian rhythms for placing telephone calls and receiving telephone calls. These rhythms are partly structured by the way in which older adults allocate their communication time over the day. In addition, despite minor differences between circadian rhythms for outgoing and incoming calls, our analysis suggests the two rhythms could be synchronized.

Conclusions

These results suggest the existence of potential persistent and synchronized circadian rhythms in the outgoing and incoming telephone activities of older adults.
Feasibility of the Internet Attachment–Based Compassion Therapy in the General Population: Protocol for an Open-Label Uncontrolled Pilot Trial
Authors: Campos Daniel , Navarro-Gil Mayte , Herrera-Mercadal Paola , Martínez-García Laura , Cebolla Ausiàs , Borao Luis , López-Del-Hoyo Yolanda , Castilla Diana , del Río Eva , García-Campayo Javier , Quero Soledad
Published: January 2020

Background

Compassion-based interventions delivered over the internet are showing promising results for the promotion of psychological health and well-being. Several studies have highlighted their feasibility, acceptance, and preliminary efficacy. However, this is an incipient field of research, and to the best of our knowledge, there are no data available from Spanish-speaking countries.

Objective

The aim of this study is to investigate the feasibility, acceptance, and preliminary efficacy of the Internet Attachment–Based Compassion Therapy (iABCT), a web-based version of the Attachment-Based Compassion Therapy, in Spanish speakers from the general population.

Methods

This feasibility study features a single-arm, uncontrolled, within-group design with an embedded qualitative and quantitative process evaluation at baseline, immediately after the intervention and at the 3-month follow-up. A minimum of 35 participants from the general population will be allocated to iABCT. Feasibility measures will include attrition rate, patterns of use of the web-based system, and participants’ acceptability, usability, and opinion. The primary outcome was measured using the Pemberton Happiness Index. Secondary outcomes were measured using the Compassion Scale, Self-Compassion Scale, Forms of Self-Criticizing/Attacking and Self-Reassuring Scale-Short form, Five Facets of Mindfulness Questionnaire, Relationships Questionnaire, General Health Questionnaire, Non-Attachment Scale, International Positive and Negative Affect Schedule Short Form, Purpose-In-Life Test, and difficulties regarding the practice of compassion (Compassion Practice Quality Questionnaire). Mixed models will be used to evaluate primary and secondary outcome measures. A qualitative content analysis of the participants’ qualitative responses will also be performed.

Results

Enrollment started in February 2020 and will be finished in April 2020. Data analysis will start in October 2020.

Conclusions

To our knowledge, this study will, for the first time, show data on the feasibility, acceptability, and preliminary efficacy of web-based compassion (and self-compassion) training—that is, the adapted iABCT—in Spanish speakers from the general population. Further aspects of their implementation (ie, facilitators, barriers, and unwanted effects) and mechanisms of change will be investigated. This study will allow the revision and fine-tuning of the developed intervention, study design, and planning procedures, as well as the initiation of a future randomized controlled trial.

Trial Registration

Clinicaltrials.gov: NCT03918746. Registered on April 17, 2019. Protocol version 1, 6 March 2019.

International Registered Report Identifier (IRRID)

PRR1-10.2196/16717
Pengukuran Frekuensi Bunyi Saron Demung Laras Pelog Gamelan Jawa Menggunakan Perangkat Lunak Visual Analyser (Halaman 73 s.d. 76)
Authors: - Mitrayana , Cytasari V.J.
Published: January 2020

Penelitian ’PENGUKURAN FREKUENSI BUNYI SARON DEMUNG LARAS PELOG GAMELAN JAWA MENGGUNAKAN PERANGKAT LUNAK VISUAL ANALYSER‘ ditujukan untuk mengkaji karakteristik frekuensi bunyi pada Gamelan khususnya Saron Demung Laras Pelog. Saron Demung Laras Pelog merupakan alat musik tradisional yang  belum mempunyai standar nada seperti alat musik lainnya. Penyelarasan gamelan dewasa ini biasanya dilakukan oleh para ahli, yaitu hanya dengan menggunakan rasa jiwa berdasarkan pengalamanya. Tiap gamelan yang dihasilkan memiliki perbedaan pada setiap penyelarasnya. Sehingga diharapkan hasil dari penelitian ini dapat digunakan untuk penentuan standarisasi pada alat musik gamelan khususnya Saron Demung Laras Pelog. Penelitian dilakukan dengan menggunakan mikrofon yang dihubungkan langsung ke komputer jinjing. Komputer jinjing ini telah dilengkapi dengan perangkat lunak Visual Analyser yang langsung dapat menampilkan spektrum dan nilai frekuensi dari bunyi gamelan yang diamati. Dengan melakukan penabuhan yang konstan pada setiap wilahannya maka dapat diperoleh nilai frekuensi resonansi dari Saron Demung Laras Pelog baik langsung pada kolom frequency meter maupun dengan menggeser kursor pada puncak amplitudo maksimumnya. Frekuensi resonansi rata-rata (f0) dan nilai ketidakpastian ralatnya (∆f0) yang diperoleh dari penelitian untuk Saron Demung Laras Pelog berturut-turut dari wilahan 1 sampai 7 yaitu (289 ± 6)  Hz, (319 ± 7) Hz, (336 ± 7) Hz, (392 ± 8)  Hz, (429 ± 8) Hz, (455 ± 8) Hz, dan (505 ± 9) Hz.
Kajian Sistem Pendukung Pengambilan Keputusan (DIFURAD) Pada Sistem Kedaruratan Nuklir Kawasan Mediterranean (Halaman 90 s.d. 93)
Authors: Khusyairi Akhmad
Published: January 2020

Kajian Sistem Pendukung Pengambilan Keputusan (DIFURAD) Pada Sistem Managemen Kedaruratan Nuklir Kawasan Mediterranean. Sebagian besar Negara-negara Eropa memenuhi kebutuhan energi mereka dengan memanfaatkan energi nuklir. Dalam hal kedaruratan nuklir yang terjadi pada PLTN di Negara-negara Eropa akan memberikan dampak radiologi yang cukup serius di kawasan Mediterranean. Saat ini ENEA telah mengembangkan system pendukung pengambilan keputusan dalam system manajemen kedaruratan nuklir, DIFURAD.  Hingga 2013, ENEA telah mengembangkan 2 skenario kecelakaan nuklir yang terjadi lintas perbatasan dan dispersi zat radioaktif ke laut Mediteranian melalui sungai. Kedua skenario yang telah dibangun dapat mensimulasikan kemungkinan dampak radiologi lingkungan dan yang mungkin terjadi pada masyarakat kawasan Mediterranian serta memberikan informasi yang diperlukan dalam manajemen kedaruratan nuklir. Beberapa negara ASEAN saat ini telah memutuskan untuk memanfaatkan teknologi nuklir untuk memenuhi kebutuhan energy listrik mereka, DIFURAD merupakan salah satu model yang dapat digunakan sebagai acuan dalam membangun sistem kedaruratan nuklir regional.  Kajian ini dilakukan dengan menggunakanan metode studi literatur.
Pengaruh Model Pembelajaran Anchored Instruction terhadap Penguasaan Konsep dan Kemampuan Pemecahan Masalah Fisika Siswa Kelas X (Halaman 8 s.d. 12)
Authors: Hafizah Ellyna , Hidayat Arif , - Muhardjito
Published: January 2020

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran anchored instruction terhadap penguasaan konsep dan kemampuan pemecahan masalah Fisika. Penelitian ini merupakan penelitian kuasi eksperimen menggunakan dua kelas yaitu kelas eksperimen dan kelas kontrol. Populasi penelitian ini adalah seluruh kelas X MAN 2 Martapura semester genap tahun ajaran 2013/2014. Sampel terdiri atas kelas eksperimen dan kelas kontrol yang dipilih secara acak. Kelas eksperimen belajar menggunakan anchored instruction dan kelas kontrol belajar menggunakan inkuiri terbimbing. Pembelajaran dilakukan pada materi suhu dan kalor. Data yang didapatkan dianalisis menggunakan multivariate of anova. Pengaruh pembelajaran diuji dengan uji Tukey. Hasil analisis menunjukkan penguasaan konsep dan kemampuan pemecahan masalah Fisika kelas eksperimen lebih baik daripada kelas kontrol.
Dinamika Model Spin XY 2 Dimensi
Authors: Chistivina Mega , Anugraha Rinto
Published: January 2020

Simulasi model spin XY 2 dimensi telah berhasil dilakukan menggunakan metode Monte Carlo dalam bahasa pemrograman C. Dalam simulasi ini, selain diperoleh gambaran tentang perilaku spin dalam suhu tertentu secara visual, diperoleh pula hasil kuantitatif berupa nilai besaran-besaran energi Hamiltonian, kapasitas panas khusus, magnetisasi, suseptibilitas magnetik dan kuantitas vortex yang terbentuk dalam sistem dengan suhu dibawah dan diatas suhu kritis. Lebih lanjut, diperoleh suhu kritis yang berbeda untuk kedua ukuran sistem yang diuji, yaitu Tc sebesar 1.1 untuk sistem dengan ukuran 16 x 16 dan Tc sebesar 1.0 untuk ukuran 256 x 26, membuktikan bahwa suhu kritis dalam sistem ukuran terbatas akan mengalami pergeseran. Nilai Tc yang diperoleh dari kedua sistem berukuran terbatas ini cukup mendekati nilai suhu kritis ideal pada transisi Kosterlitz-Thouless yaitu TKT = 0.892.kata kunci: model spin; 2D XY; simulasi Monte Carlo; transisi Kosterlitz-Thouless transition
Pembelajaran IPA pada Konsep Kalor yang Berorientasi Doing Science
Authors: Hartanto Theo Jhoni
Published: January 2020

Tujuan dari penelitian ini adalah untuk mengimplementasikan pembelajaran IPA aktif berorientasi doing science dalam pembelajaran konsep kalor.  Penelitian ini merupakan penelitian pra eksperimen dengan sampel penelitian 15 siswa kelas VII di salah satu SMP di, Kalimantan Tengah. Data kuantitatif diperoleh melalui tes kinerja dan tes kognitif yang kemudian dianalisis secara deskriptif. Hasil analisis menunjukkan bahwa  80% siswa memiliki keterampilan proses sains dengan kategori baik. Nilai rata-rata yang diperoleh berdasarkan analisis tes kognitif pada konsep kalor adalah 72,20 dan 73% siswa memperoleh nilai di atas 70. Masih ditemukan beberapa pemahaman konsep siswa yang salah terhadap konsep kalor. Berdasarkan temuan itu, dapat disimpulkan bahwa sebagian besar siswa kelas VII di sekolah sasaran penelitian ini memiliki keterampilan proses sains yang baik setelah pembelajaran yang berorientasi doing science. Namun demikian, masih ada beberapa pemahaman yang salah ditemukan pada konsep kalor.
ANALISIS LOG TOC PASSEY DAN PENYEBARAN SERPIH PINIYA MENGGUNAKAN METODE SEISMIK INVERSI, CEKUNGAN AKIMEUGAH
Authors: Anggraeni Winda Putri , Setyowiyoto Jarot , Anggara Ferian
Published: January 2020

Cekungan Akimeugah memiliki potensi hidrokarbon dengan adanya beberapa rembesan minyak dan gas bumi disekitar daerah penelitian. Hal ini mengindikasikan adanya sistem minyak dan gas bumi yang bekerja pada daerah tersebut. Serpih Piniya merupakan salah satu formasi yang berpotensi menjadi batuan induk sekaligus batuan reservoar yang baik. Batuan induk yang mengandung hidrokarbon ditentukan oleh kuantitas material organik (Total Organic Carbon). Untuk itu, perlu diketahui kuantitas material organik (TOC) serta penyebaran dari Serpih Piniya.Serpih Piniya disusun oleh litologi dominan serpih dengan sisipan batulanau dan batupasir. Formasi ini diendapkan pada lingkungan laut dangkal (shallow marine) dengan asosiasi fasies offshore transition hingga offshore. Jumlah kuantitas material organik (TOC) dari data sampel sebesar 0.552 wt% termasuk ke dalam kategori batuan induk yang bersifat cukup (fair). Tipe kerogen Serpih Piniya adalah tipe II – III yang dapat menghasilkan hidrokarbon minyak dan gas. Litofasies serpih yang dapat menghasilkan hidrokarbon adalah organic shale. Interval organic shale terdapat pada sumur AK-6 sebanyak 46 zona dan sumur AK-9 sebanyak 34 zona. Perhitungan TOC Passey menghasilkan nilai TOC rata-rata sebesar 0.527 wt% menandakan Serpih Piniya berada pada kategori batuan induk yang bersifat cukup.Penyebaran nilai TOC menggunakan seismik inversi untuk mengetahui model geologi bawah permukaan. Penyebaran nilai TOC tinggi ditandai dengan nilai impedansi akustik yang rendah, area tersebut terletak pada bagian rendahan daerah penelitian. Area sweet spot secara umum berada disekitar sumur AK-2, area tersebut memiliki nilai TOC berkisar 0.552 wt% dengan ketebalan Serpih Piniya kurang lebih sebesar 1200 m.
Pengaruh Penambahan (MoO3-SiO2) pada Coating AlNiCrCu yang difabrikasikan dengan Metode Paduan Mekanik
Authors: Hariyati Hariyati
Published: January 2020

Telah dilakukan penelitian tentang sintesa lapisan komposit AlNiCrCu-(MoO3-SiO2) pada pelat baja karbon rendah. Material  coating AlNiCrCu-(MoO3-SiO2) dicampur dan dimiling untuk menjadi serbuk halus dengan menggunakan metode paduan mechanical alloying (MA). Hasil penampang lintang (cross-section) dapat memperlihatkan bahwa coating AlNiCrCu-(MoO3-SiO2) telah berhasil terdeposisi dengan baik pada substrat baja karbon rendah dengan menggunakan metode paduan mechanical alloying (MA) dan memiliki nilai rata-rata ketebalan lapisan permukaan sebesar 38,162 µm-52,662 µm. Hasil analisa surface morfology permukaan dengan penambahan (MoO3-SiO2) pada penambahan konsentrasi (MoO3-SiO2) sebesar 42% memiliki paduan morfologi  yang paling baik daripada sampel yang lain karena memiliki poros yang lebih sedikit. Hasil uji oksidasi cyclic pada suhu 800°C selama 10 siklus selama 200 jam (perhari 20 jam) dengan menggunakan muffle furnace menunjukkan bahwa semakin meningkat pertambahan massa maka difusi oksigen yang masuk pada permukaan semakin cepat.
Asas Kebiasaan Pemberian Uang Panjar dalam Transaksi Jual Beli Era Pasar Bebas
Authors: Holijah Holijah
Published: January 2020

AbstractRecently, the activities of economic and as well as various model of transaction has always been developed. However the transaction with this system (voorschot) always happened in the society. This research is aiming to give a concept and practice by consequences of law from a custom giving a voorschot  in transaction. This research is using a documentary and library research. The result of this study showed that with a concept and practice of giving voorschot who is recognized by positive law as well as customary law, civil law and islamic law. Then in the development of the practice this transaction of buying a product with this system is approved as a sign of agreement and can be allowed to held it. IntisariPemberian uang panjar dalam transaksi jual beli suatu produk barang adalah merupakan kebiasaan yang terjadi di masyarakat Indonesia. Transaksi jual beli produk barang sebagai upaya dalam memenuhi kebutuhan dan cara mendistribusikan kebutuhan, yang mana konsep dan praktiknya melandaskan pada filosofi yang berbeda-beda. Pemberian uang panjar sebagai konsep perjanjian, adalah selaras dengan asas kebiasaan dalam perjanjian, sehingga uang panjar sebagai uang tanda jadi dan uang muka dalam transaksi jual beli produk barang juga dalam praktik tergantung kesepakatan akan di kembalikan atau tidak, termasuk bagian harga jual ataupun tidak. Sementara itu, mengenai pemberian uang panjar sebagai uang muka jika terjadi pembatalan, maka uang panjar sebagai uang muka dikembalikan.
THE TRADE GOVERNANCE FRAMEWORK PROVIDED BY TRIPS AND CLAIM OF ‘PRO­-DEVELOPMENT’ AGENDA
Authors: Putri Karina Dwi Nugrahanti
Published: January 2020

Having encountered objection from developing countries during previous negotiations, the WTO has tried to soften the framework of trade liberalisation in subsequent negotiations, held in Doha in 2001. In this round, the WTO gave rise to the ‘pro-development framework’ to attract fuller participation by developing countries. However, the development agenda had been assumed as a strategy in maintaining the superiority of advanced industrialised countries in applying ‘organised imbalance. This essay will discuss the implementation of special and differential treatment (SDT) for developing countries within TRIPS provisions. The promise of help through SDT for developing countries (as the majority of importer country of patented rights) is merely used as the medium with which to prioritise MNCs from developed countries which operate in developing countries.
JOB SATISFACTION OF ACADEMIC STAFF IN THE HIGHER EDUCATION SYSTEM OF SERBIA: A PILOT STUDY
Authors: Slavić Agneš , Avakumović Julija , Berber Nemanja
Published: January 2020

In the turbulent business environment of today, the competitiveness of all organizations is primarily based on intangible resources. Due to global competition, the permanent actualization of employee competencies is imperative for the long-term survival of organizations. The higher education system bears a special responsibility in this process, as it provides an upgrade for the development of the previously obtained competencies of future employees. Higher education is the system focused on dual core functions of knowledge creation and knowledge transmission through the processes of research and teaching (Houston et al, 2006, 17). To ensure high-level competences in future employees, it is crucial for the higher education system (teaching staff) to provide students with the latest knowledge in their field. The job satisfaction of academic staff is reflected in the quality of teaching and communicating with students (Runhaar, 2017, 646-647). The aim of this paper is to determine the level of general and partial satisfaction of teaching staff at the institutions of higher education in the Republic of Serbia. The method implemented for determining the level of satisfaction, was Spector’s Job Satisfaction Survey – JSS (Spector, 1985), in the form of an on-line questionnaire. The pilot research was conducted in December 2018 and January 2019. The sample consists of 58 respondents - teachers from higher educational institutions in the Republic of Serbia. The results of general job satisfaction survey indicate that teachers are generally ambivalently satisfied with their job, they are neither satisfied, nor dissatisfied. The results of partial satisfaction show that teaching staff is most satisfied with the nature of their job.
„SERBIAN SOKO“ IN CLEVELAND, OHIO
Authors: Pantelić-Babić Kristina , Pavlović Petar , Živanović Nenad
Published: January 2020

The beginnings of Sokolism bind to the second half of the 19th century, namely to the Czech Miroslav Tyrš and its system of physical exercise. After the founding in the Czech Republic, Sokol movement began to spread in all Slavic countries as well as in those where Slavic nations lived. In this way, Sokolism arrived among Serbs who lived in America (USA), and they began to accept the idea of Sokolism in the mid-1907. In early 1909 began to appear the first initiatives for the establishment of Serbian Soko Societies. During 1909 two societies were founded, the in the next year five more, in 1911 three societies and in 1912 more than ten. In the second half of 1911 was established the union of Serbian Soko societies in America called Serbian Soko Parish in America (SSPA). Serbian Soko Society in Cleveland, Ohio, which is also the main subject of this research, was founded in the first half of 1912. The aim of the authors is to explore and present the exact date of the founding of this Society, the main initiators and founders, members and activities of the Society during its work. In this study authors used the historical method.
PREVALENCE OF SCOLIOSIS IN ELEMENTARY SCHOOL STUDENTS AGED 8-11 YEARS
Authors: Haryono Ignatio Rika , Prastowo Nawanto Agung
Published: January 2020

Adolescent idiopathic scoliosis (AIS) is a spinal abnormality commonly found in children and adolescents with a prevalence rate of 0.5-5.2%. Data on scoliosis in Indonesia is yet to be available. Our study was aimed at screening and comparing school children with normal posture and with suspected scoliosis (SS). 1059 elementary school students (477 boys, 582 girls) from grade 3 to grade 6 in Jakarta participated in this study. Body mass and height were measured according to the standard technique. Axial rotation of the spine was measured using a scoliometer. Results were classified into two groups: normal if the axial rotation angle was <5° and scoliosis was suspected if the angle was ≥5°. An independent t-test was used to analyze anthropometric differences between the normal and SS group. Statistical significance was set at p<0.05. 74 (7%) of the 1059 students were SS, consisting of 24 (5 %) boys and 50 (8.6 %) girls (OR 1.98, P=0.004). Students at the age of 10 had the highest incidence of scoliosis (27 or 10.1%). Girls with SS were significantly taller and with lower BMI values (138.6 cm vs 134.6 cm, p=0.014; 16.95 kg/m2 vs 18.50 kg/m2, p=0.028). The scoliosis rate in elementary students in Jakarta was about 7 % with higher prevalence in girls.
DECISION MAKING TO VISIT KOPI LUWAK AGROTOURISM (Case Study of Kopi Luwak Cikole in Cikole Village, Babakan Village, Lembang District)
Authors: Fadhila Elma Dian , Deliana Yosini
Published: January 2020

The agricultural sector in tourism is often called agrotourism. Kopi Luwak (Civet Coffee) Cikole, located in Kampung Babakan, produces Luwak coffee that applies animal welfare, so that agrotourism is awarded as Animal Wellfare-based agro-tourism. Kopi Luwak Cikole offers educational tours for its visitors. Visitorsto agrotourism are thought to have a specific purpose. Various people who visit Agro Tourism are seen from the characteristics of visitors and visiting decision making. The purpose of this study is to identify the characteristics and consumer decision-making processes of Kopi Luwak Cikole. Data analysis was carried out with descriptive analysis techniques. The results of this study indicate that the characteristics of Kopi Luwak Cikole respondents are mostly resident of Malaysia, male, 36-45 years old, their last education is Bachelor, have occupation as a Private or Government Employee with monthly income ≥ Rp. 5,000,001. The visiting decision at the need recognition stage is the motivation to visit agro tourism. This is  because attractive facilities with benefits sought during a visit are adding to the knowledge of cultivation and process of civet coffee. Evaluation phase, consideration for visiting is because of civet coffee education. Furthermore, the decision to visit is carried out in a planned manner which on average is carried out during holidays. The level of satisfaction after post-visit, shows visitors feel satisfied with the facilities in agrotourism.
PENGGUNAAN LEM SEPATU DAN GANGGUAN KESEHATAN PEKERJA INDUSTRI SEPATU DI CIOMAS, BOGOR
Authors: Laelasari Eva , Kristanti Dewi , Rahmat Basuki
Published: January 2020

ABSTRACT 

The use of glue in shoe manufactures may cause health impacts among workers due to hazardous chemical exposure in glue such as benzene and toluene. The government has issued policies to prevent the workers from occupational illness by reducing the hazardous chemical exposure in the workplace. This study was conducted to find out health impacts due to benzenae and toluene exposure from the use of glue in the workplace of shoe manufactures in Ciomas, Bogor in 2017. Design of the study was cross sectional with variables of benzene and toluene content in indoor workspace, consentration of urinary S-PMA, and perceived health symptoms of workers. Samples of 34 respondents were obtained from 5 selected workshop. Analysis of the data was carried out descriptively. It was found that the content of benzene and toluene in glue are 0.1% and 55% respectively, indoor benzene vapor was below detection limit of the instrument (undetected), and concentration of urinary S-PMA was 0.24 µg/g creatinine. There was no benzene exposure to the workers in this study. High percentage of worker risk behavior were smoking, the use of PPE, and hand washing. Perceived symptoms of workers (more than 60%) were fatigue, headache, tingling. It is necessary to improve workplace with healthier and more conducive environment, and educate workers to use the PPE.

Keywords: Shoe glue, benzene, toluene, exposure,  small scale shoe manufacture

 

ABSTRAK 

Penggunaan lem pada industri sepatu kemungkinan memberikan dampak kesehatan terhadap pekerja karena lem biasanya mengandung bahan berbahaya, seperti benzena dan toluena. Pemerintah sudah berupaya membuat kebijakan untuk mengendalikan penyakit akibat kerja, salah satunya adalah mengurangi pajanan bahan kimia berbahaya.  Penelitian ini bertujuan untuk  mengetahui dampak kesehatan akibat pajanan benzena dan toluena yang berasal dari penggunaan lem di tempat kerja di sentra industri sepatu Ciomas, Bogor pada tahun 2017. Desain penelitian adalah potong lintang dengan variabel kandungan benzena dan toluena di udara ruang kerja, kandungan S-PMA dalam urin, dan gangguan kesehatan yang dialami oleh pekerja. Jumlah sampel pekerja sebanyak 34 orang yang berasal dari 5 bengkel kerja. Analisis data dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa kadar benzena dan toluena dalam lem masing-masing adalah 0,1% dan 55%, kadar uap benzena di udara ruang kerja berada di bawah limit deteksi alat (tidak terdeteksi), dan rerata kandungan S-PMA dalam urin adalah 0,24 µg/g kreatinin. Tidak terjadi pajanan benzena  terhadap pekerja industri sepatu di lokasi penelitian. Perilaku berisiko pekerja dengan persentase cukup tinggi adalah merokok, penggunaan APD, dan cuci tangan. Keluhan/gangguan kesehatan yang dirasakan (lebih dari 60%) adalah cepat lelah, sakit kepala, kesemutan. Perlu perbaikan lingkungan kerja yang lebih sehat dan nyaman, dan mengedukasi pekerja untuk menggunakan APD.

Kata kunci: Lem sepatu, benzena, toluena, pajanan, industri sepatu rumahan
PELAYANAN PEMERIKSAAN KEHAMILAN BERKUALITAS YANG DIMANFAATKAN IBU HAMIL UNTUK PERSIAPAN PERSALINAN DI INDONESIA
Authors: Dharmayanti Ika , Azhar Khadijah , Tjandrarini Dwi Hapsari , Hidayangsih Puti Sari
Published: January 2020

ABSTRACT

Antenatal care (ANC) is a prevention healthcare for maternal health and their babies. In order to fulfill the needs of them, an accessible health facility that provides ANC with qualified services for the community is needed. This study aims to determine the utilization of maternal health services as preparation for safe delivery. Analysis of this study used the data from National Health Indicator Survey (Sirkesnas) 2016 and Village Potential Census (Podes) 2014. The analysis technique was multivariable logistic regression. The results showed that the use of qualified ANC tended to be used by mothers who were examined by midwives in health centers, highly educated mothers, those who were living in moderate and good neighborhoods, not living in slums (social environment) and residing in Java-Bali region.  It can be concluded that midwives and location of ANC provided important role to improve the utilization of ANC services as an ideal preparation for safe delivery.

Keywords: Quality of ANC, maternal health, living environment, social environment

 

ABSTRAK

Pemeriksaan kehamilan atau antenatal care (ANC) merupakan upaya untuk menjaga kesehatan ibu hamil dan bayinya. Dalam  memenuhi kebutuhan tersebut, diperlukan fasilitas kesehatan yang mudah diakses oleh masyarakat serta pelayanan pemeriksaan ANC yang berkualitas. Penelitian ini bertujuan untuk mengetahui pemanfaatan pelayanan kesehatan ibu hamil sebagai persiapan persalinan yang aman.  Analisis menggunakan data Survei Indikator Kesehatan Nasional (Sirkesnas) tahun  2016 dan Potensi Desa (Podes) tahun 2014. Teknik analisis yang digunakan adalah regresi logistik multivariabel. Hasil uji regresi logistik multivariabel menunjukkan bahwa pemanfaatan ANC berkualitas cenderung digunakan oleh ibu yang diperiksa bidan di puskesmas, ibu berpendidikan tinggi, tinggal di lingkungan permukiman sedang dan baik, tidak tinggal di wilayah kumuh (lingkungan sosial) serta bertempat tinggal di Regional Jawa-Bali. Dapat disimpulkan bahwa bidan dan tempat ANC mempunyai peran sangat penting untuk meningkatkan pemanfaatan pelayanan ANC ideal sebagai persiapan persalinan yang aman.

Kata kunci: Pelayanan kehamilan  berkualitas, kesehatan ibu hamil, lingkungan permukiman, lingkungan sosial
Potensi Ekstrak Daun Marigold (Tagetes erecta L.) sebagai Larvasida terhadap Larva Aedes aegypti di Laboratorium
Authors: Marini Marini , Mahdalena Vivin , Ni'mah Tanwirotun
Published: January 2020

Abstract

Control of mosquito vectors by using natural ingredients is being developed intensively. Marigold (Tagetes erecta) was widely used as a mosquito repellent plant. The results of research before had found that marigold leaf extract has a repulsive effect on Aedes aegypti mosquitoes. This study aimed to identify the potential of marigold leaf extract as larvacide against Ae. aegypti larvae in the laboratory. The material used in this research was extracts of marigold leaves. Larvacide test was carried out by dissolving of extract in water at the concentration of 2,000 ppm, 4,000 ppm, 6,000 ppm, 8,000 ppm, and 10,000 ppm. The larvae used was Ae. aegypti larvae as many as 25 larvae each five treatment of replications. Probit analysis was conducted on larval mortality after 24 hours of exposure. The results of the probit analysis showed that the estimated concentration of extracts that could result in larval mortality up to 95% (LC95) was 7,456 ppm. From the result we can conclude that ethanol extract of marigold leaves (T. erecta L. ) has the biolarvacidal activity against larvae.

Abstrak

Pengendalian vektor nyamuk dengan memanfaatkan bahan alam makin banyak dikembangkan. Marigold (T. erecta) merupakan tumbuhan yang banyak dimanfaatkan  sebagai tanaman pengusir nyamuk. Hasil penelitian sebelumnya menemukan bahwa ekstrak daun memiliki daya tolak terhadap nyamuk Ae. aegypti. Penelitian ini bertujuan untuk melihat potensi ekstrak daun marigold sebagai larvasida terhadap larva Ae. aegypti instar III di laboratorium. Bahan yang digunakan pada penelitian ini adalah ekstrak etanol daun marigold hasil ekstraksi dari penelitian sebelumnya. Uji larvasida dilakukan dengan melarutkan ekstrak dalam air pada konsentrasi 2.000 ppm, 4.000 ppm, 6.000 ppm, 8.000 ppm, dan 10.000 ppm. Larva yang digunakan yaitu larva Ae. aegypti sebanyak 25 larva tiap perlakuan dengan lima ulangan. Dilakukan analisis probit terhadap kematian larva setelah 24 jam paparan. Hasil analisa probit menunjukkan perkiraan konsentrasi ekstrak yang mampu mengakibatkan kematian larva hingga 95% (LC95 ) adalah 7.456 ppm. Ekstrak etanol daun marigold (T.erecta L.) memiliki potensi sebagai biolarvasida terhadap larva Ae. aegypti.
Comportamiento político en la tensión libre comercio-proteccionismo: Caso de dumping LAICA-La Maquila S.A.
Authors: Julia Paola Barrantes Aguilar
Published: January 2020

El objetivo es analizar el comportamiento político del sector azucarero costarricense en la tensión libre comercio-proteccionismo, en el caso de dumping entre LAICA y La Maquila Lama S. A., mediante entrevistas semiestructuradas y monitoreo de medios de comunicación; se realiza un análisis de coyuntura del caso contemplando las categorías de análisis: acontecimientos, actores, escenarios, tácticas y estrategias. Se identifica que la discusión entre el libre comercio y el proteccionismo es imaginaria, en el tanto estos dos modelos son, en principio, modelos teóricos de economía. En la práctica, no existe ninguna economía de mercado completamente desregulada ni tampoco ninguna completamente protegida. Por ello, una conclusión para este estudio es que ambos modelos coexisten dentro del sistema económico y en diferentes niveles dentro de las economías de los países.
MANAJEMEN LEMBAGA TAMAN KANAK – KANAK BERPRESTASI DALAM RANGKA MECETAK ANAK USIA DINI YANG UNGGUL DAN BERKARAKTER (Studi Kasus di TK Islam Waladun Solih Desa Jayagiri Kecamatan Lembang Kabupaten Bandung Barat )
Authors: Patimah Rina Siti , Nurhayati Sri
Published: January 2020

Tujuan dari penelitian ini adalah untuk mendeskripsikan : perencanaan, pelaksanaan, hasil pelaksanaan, evaluasi dan kendala yang dihadapi lembaga sehingga bisa menjadi lembaga yang berprestasi di TK Islam waladun Sholih desa Jayagiri Lembang. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif dengan subjek penelitian yaitu satu orang pengelola dan tiga orang guru. Tehnik pengumpulan data yang digunakan adalah wawancara, observasi dan dokumentasi.Hasil penelitian ini adalah : (1) Perencanaan yang dilakukan pengelola TK yaitu Kepala sekolah diantaranya membuat penyusunan program tahunan, pembagian tugas guru, dan persiapan pengadaan sarana dan prasarana, (2) Pelaksanaan program pendidikan yang dilakukan dengan baik, keterlibatan Kepala Sekolah dan semua guru dalam setiap kegiatan yang diselenggarakan, (3) Hasil pelaksanaan program yang dilakukan melalui evaluasi, dan monitoring dari Kepala sekolah dalam semua aspek manajemen lembaga sekolah, (4) beberapa kesulitan yang dihadapi yaitu keterbatasan sarana dan prasarana, kurangnya peran serta orang tua dan kurangnya  tenaga pendidiki (5) Upaya- upaya yang dilakukan dalam pelaksanaan program pendidikan di Lembaga TK dengan cara menambah sarana dan prasarana, mengadakan kegiatan parenting dan mengikuti seminar dan pelatihan yang dilaksanakan untuk meningkatkan kompetensi guru, (6) Adanya bantuan dan prioritas dari pemerintah setelah menjadi lembaga berprestasi. Rekomendasi penelitian mencakup pengoptimalan pelaksanaan program – program pendidikan, meningkatkan pengelolaan sarana dan prasarana sesuai delapan standar pendidikan, menambah tenaga pendidik, meningkatkan kompetensi guru dan mempertahankan semua prestasi lembaga yang telah didapat.
LITERASI INFORMASI DALAM KERANGKA PENGEMBANGAN PENDIDIKAN MASYARAKAT
Authors: Mulyono Dinno , Ansori Ansori
Published: January 2020

Pemanfaatan teknologi dan informasi di tengah masyarakat membutuhkan sebuah kerangka yang menyeluruh, terkait dengan pendidikan dan implementasinya di tengah kelembagaan satuan pendidikan masyarakat, terutama berhubungan dengan berbagai pendekatan dalam proses pengelolaan informasi untuk peningkatan kualitas kehidupan masyarakat, tidak hanya berkaitan dengan pengembangan kompetensi membaca, menulis dan berhitung, tapi berhubungan dengan manajemen informasi itu sendiri agar dapat memberikan makna dan manfaat bagi kualitas kehidupan masyarakat. Dengan pendekatan pendidikan masyarakat, maka dapat dikembangkan sebuah model pembelajaran dengan memanfaatkan aksesibilitas dan kualitas teknologi informasi untuk menunjang program pemberdayaan yang ada. Termasuk memberdayakan satuan pendidikan masyarakat untuk memberikan dukungan atas pemanfaatan informasi dalam peningkatan kapasitas masyarakat itu sendiri.