bluuebunny/crossref_metadata_2025 huggingface dataset:
ECONOMETRIC MODEL OF REGIONAL DEVELOPMENT BASED ON MEDICAL SAVINGS ACCOUNTS
Authors:   Bauman Moscow State Technical University, Moscow, Russia, Kostyrin Evgeny V. , HE Pingping ,   Bauman Moscow State Technical University, Moscow, Russia
Published: November 2021

An econometric model of the development of the regions of the Russian Federation based on medical savings accounts (MSA) has been developed. The presence of the phenomenon of multicollinearity in the model based on the correlation matrix is verified and its statistical significance is evaluated according to the Fisher criterion. The practical implementation of the developed econometric model is made on the example of the Southern Federal District and separately the Rostov region. It is shown that as a result of the practical application of the developed econometric model, the complex indicator of the level of investment attractiveness of the Rostov region increases from 1.872 to 2.084, i.e. by 11.3%, which moves it in the rating of investment attractiveness according to the evaluation methodology of the rating agency Expert-RA from ninth to sixth place. As a result of the practical application of the developed econometric model and the de-termination of the level of investment attractiveness based on the MSA, the Krasnodar region received the highest rating for the Southern Federal District, the level of its investment attractiveness according to the method of econometric modeling based on the MSA was 2.37, the Republic of Kalmykia received the lowest rating for this indicator, the investment attractiveness of this region, calculated according to the developed methodology, was 0.183. It is concluded that the highest ratings from the point of view of investment attrac-tiveness in modeling are obtained by regions that invest in the development of the MSA system, since factors that depend on the MSA have a positive impact on the assessment of the level of development of regions.
EXPERIENCE OF USING THE CLUSTER APPROACH IN ASSESSING THE SUSTAINABLE DEVELOPMENT OF THE MOUNTAINOUS TERRITORIES OF THE NORTH CAUCASUS
Authors:   North-Caucasian Mining and Metallurgical Institute, Vladikavkaz, Russia, Batyaeva Rita I. , Shelkunova Tat’yana G. ,   North-Caucasian Mining and Metallurgical Institute, Vladikavkaz, Russia, Khetagurova Irina Yu. ,   North-Caucasian Mining and Metallurgical Institute, Vladikavkaz, Russia, Khetagurova Tamara G. ,   North-Caucasian Mining and Metallurgical Institute, Vladikavkaz, Russia
Published: November 2021

The article provides an overview of the effects of the resonant impact of clusters on the ability of mountain areas to adapt to the modern realities of the technological level, as well as the ability to apply innovations, attract investment in the agro-industrial and tourist cluster. A panel of indicators is presented that provides correct comparability of achievements and reflects information for aggregation by various parameters of the economic and geographical indicators of the region: the national environmental rating of the subjects of the North Caucasus Federal District; indicators of sustainable development of the Russian Federation and the North Caucasus Federal District; investment risk of the republics of the North Caucasus Federal District; the main economic and social indicators of the RSO-Alania. It is established that the geoinformation study of the use of a multicomponent indicator of the state of mountain territories is the basis for determining the vector of their further socio-economic development and justifying appropriate management decisions to stabilize economic development. The peculiarity of the approach is the selection of criteria that will be used in the development of mechanisms for the sustainable development of mountain territories according to the target indicators, in accordance with the UN resolution "Transforming our world in the field of sustainable develop-ment for the period up to 2030".
INSTITUTIONAL DESIGN OF THE PROCESSES OF STRATEGIC DEVELOPMENT OF THE ARCTIC ZONE OF THE RUSSIAN FEDERATION
Authors:   Luzin Institute of Economic Problems of the Kola Scientific Center of the Russian Academy of Sciences, Murmansk, Russia, Shchegol'kova Asya A.
Published: November 2021

The article analyzes the formation of processes of institutional regulation of socio-economic activity in the Arctic Zone of the Russian Federation. An assessment of state support measures for the eco-nomic development of the Arctic space, business stimulation, increasing the investment and social attractive-ness of the Arctic Zone of the Russian Federation was given. It was revealed that the formation of the institu-tional space of the Arctic Zone of the Russian Federation would allow the Arctic regions of Russia to become the world's largest economic zone with a single set of administrative, tax and investment preferences, as well as a geopolitical tool for strengthening the regional presence of Russia in the Arctic.
ECONOMICS AND MANAGEMENT OF A MEDICAL ORGANIZATION DURING THE COVID-19 PANDEMIC
Authors:   Research Institute for Healthcare Organization and Medical Management of Moscow Healthcare Department, Moscow, Russia, Budarin Sergey S.
Published: November 2021

The article describes the economic and socio-medical indicators of the activities of medical organizations providing primary health care to the population during the spread of Covid-19 coronavirus in-fection. The differences in the values of indicators compared to the previous period are analyzed and the financial stability of medical organizations in the prevailing economic and social conditions is assessed.
TO ANALYZE THE STRUCTURE OF TAX REVENUES TO THE BUDGET OF THE REPUBLIC OF NORTH OSSETIA ALANIA BY TYPES OF ECONOMIC ACTIVITY
Authors:   North Ossetian State University after K. L. Khetagurov, Vladikavkaz, Russia, Morgoeva Alina K. , Salamova Alena E. ,   North Ossetian State University after K. L. Khetagurov, Vladikavkaz, Russia, Musaeva Kheda M. ,   Chechen State University, Grozny, Russia
Published: November 2021

The subject of the study is the analysis of the dynamics and structure of tax revenues to the consolidated budget of the Republic of North Ossetia – Alania (RSO – Alania), their impact on the economic policy of the subject under study. The relevance of the topic under study is explained by the fact that tax revenues are the most effective tool for regulating economic relations. They maintain the balance of the parties and are represented, on the one hand, by the interests of the state, and on the other – by the interests of citizens. At the level of economic activities, the indicator under study is an indicator of the turnover of industrial facilities that realize the investment and overall economic potential of the region. The components necessary to maintain or restore the most important elements of the economic policy of the region are identified. Special attention is paid to the tax analysis of economic activities in the Republic of Kazakhstan to identify the strengths and weaknesses of the economic, in particular tax, policy of the region.
EXPERT EVALUATION OF THE DRAFT FEDERAL BUDGET OF THE RUSSIAN FEDERAL BUDGET FOR 2022 AND FOR THE PLANNED PERIOD 2023–2024
Authors:   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia, Karavaeva Irina V. , Bukhvald Evgeny M. ,   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia, Kazantsev Sergey V. ,   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia, Kolomiets Andrey G. ,   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia, Lev Mikhail Yu. ,   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia, Kolpakova Irina A. ,   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia, Bykovskaya Yuliya V. ,   Institute of Economics of the Russian Academy of Sciences, Moscow, Russia; V. Ya. Kikot Moscow University of the Ministry of Internal Affairs of the Russian Federation, Moscow, Russia
Published: November 2021

Expert opinion on the Draft federal budget for 2022 and for the planning period 2023–2024 prepared taking into account the complementary provisions of the Forecast of the socio-economic develop-ment of the Russian Federation for 2022 and for the planning period 2023–2024, since both documents have a single conceptual position. A comprehensive analysis of those presented in the Explanatory Note to the Draft Federal Law “On the Federal Budget for 2022 and for the Planning Period 2023–2024” the main tasks and directions for the imple-mentation of state financial policy in the economic and social spheres. An assessment of the proposed meth-ods for solving demographic problems, the tasks of ensuring the acceleration of high-quality economic growth, the possibilities of countering challenges and threats to national security is given. The adaptability and suffi-ciency of sources of formation of federal budget revenues, directions and volumes of use of budgetary funds assessed. A detailed analysis carried out in terms of the formation of federal budget expenditures for the implemen-tation of socially oriented national programs. A forecast assessment of the effectiveness of the volumes and dynamics of financing incorporated in them during the planning period presented. Special attention in the expert opinion paid to the issues of financial support for regions and municipali-ties, the distribution of interbudgetary transfers. It pointed out that the planned financing does not correspond to the strategic priorities of spatial development. The general conclusion of the experts is that the draft federal budget aimed at ensuring financial stability and inflation targeting, but does not use financial mechanisms rationally to achieve the national objectives of Russia's socio-economic development in the areas of solving demographic problems, ensuring the accelera-tion of high-quality economic growth, improving the quality of life of the population.
THE ACTIVITIES OF THE USA AND CHINA IN THE REGIONS OF THE WORLD, AFFECTING THE REALIZATION OF RUSSIA'S INTERESTS. PART 2: ACTIVITIES OF THE UNITED STATES OF AMERICA IN THE REGIONS OF THE WORLD
Authors:   Russian Academy of National Economy and Public Service under the President of the Russian Federation, Moscow, Russia, Gordienko Dmitry V.
Published: November 2021

The strategic and doctrinal documents of the United States, China and the Russian Feder-ation set out the views of the military and political leadership of these countries on how each country presents its main priorities in the field of foreign policy and ensuring global and regional security. This will allow us to formulate the interests of Russia, the United States and China. The paper examines the interests of Russia, the United States and China in the regions of the world and identifies the priorities of Russia's activities in Europe, Central Asia and the Caucasus, the Asia-Pacific region, the Arctic, Africa, the Middle East and Latin America, a comparative assessment with the interests of the United States and China. The proposed ap-proach to assessing the impact of the possible consequences of the activities of the United States and China on the realization of Russia's interests makes it possible to identify the priorities of the policy of the Russian Federation in various regions of the world. The results of the study can be used to substantiate recommenda-tions to the military-political leadership of our country. It is concluded that the discrepancy between the inter-ests of the United States and China is important for the implementation of the current economic and military policy of the Russian Federation.
Biofilm Formation and blaOXA Genes Detection Among Acinetobacter baumannii from Clinical Isolates in a Tertiary Care Kirtipur Hospital, Nepal
Authors: Ghimire Upasana , Kandel Rupesh , Neupane Mary , Shrestha Sanjit , K C Sudeep , Khanal Santosh , Joshi Dev Raj
Published: November 2021

(1) Background: Acinetobacter baumannii has emerged as a leading cause of nosocomial infections as they are capable of evolving resistance to various classes of antibiotics. The ability of A. baumannii to form biofilm might also be associated with increased antibiotic resistance and hence treatment failure. This study was carried to associate the biofilm formation with the drug resistance pattern of A. baumannii and to detect blaOXA-23, blaOXA-24, and blaOXA-51 from carbapenem resistance isolates. (2) Methods: Among different clinical samples, a total of 19 Acinetobacter spp. were identified with conventional microbiological procedures. The biofilm production was determined by a quantitative adherence assay. The antimicrobial susceptibility test was carried out by the Kirby-Bauer disc diffusion method, carbapenemase production detection was confirmed by Modified Hodge Test. And target resistant genes were detected by polymerase chain reaction. (3) Results: Out of 90 clinical specimens, 64.44% (58/90) showed bacterial growth. Whereas, 32.75% (19/58) isolates were identified as A. baumannii. Among all A. baumannii isolates, 84.21% (16/19) were multidrug-resistance and 63.16% (12/19) carbapenem resistance phenotypically. blaOXA-51 was detected in all the isolates and blaOXA-23 was detected only in 63.16% (12/19) isolates. However, blaOXA-24 was not detected in any of the isolates. Among A. baumannii, 89.47% (17/19) isolates produced biofilm with 47.37% (9/19) strong biofilm producers. (4) Conclusions: In the majority of MDR A. baumannii, blaOXA-51 and blaOXA-23 were detected as the determinant factor for carbapenem resistance having a direct relation with biofilm formation. This study provided a valuable clue for the management of A. baumannii infections in clinical settings.
COVID-19: An Updated Situation from Singapore
Authors: Loo Ke-Yan , Thye Angel Yun-Kuan , Law Lydia Ngiik-Shiew , Law Jodi Woan Fei
Published: November 2021

Since the first reports of COVID-19 in 2019, the viral respiratory disease has spread across nations, sending the world into a global pandemic. The pandemic has heavily impacted the public health of the global community. Over 237 million confirmed cases have been reported, and more than 4.8 million lives have been lost due to the novel coronavirus. In Singapore, the government quickly took action in the early stages of the pandemic to limit the spread of the virus to protect the local communities from the disease. Singapore has been able to keep their confirmed COVID-19 cases and deaths at low numbers by implementing movement restrictions, raising public awareness, mask mandates, social distancing, providing free vaccinations for the public, and utilizing advancements in technology for contact tracing. The public has also upheld their social responsibility in cooperating with the Singaporean government to control the disease spread. COVID-19 is now moving into an endemic phase in Singapore as the vaccination rates are at an all-time high resulting in lower death rates, and the confirmed cases are primarily mild to asymptomatic. Singapore has set a precedent for how pandemics can be handled in the future to minimize mortality rates and protect public health.
Analisa Dosis AB Mix Terhadap Nilai TDS Dan Pertumbuhan Pakcoy Secara Hidroponik
Authors: Sulistyowati Lilik , Nurhasanah Nurhasanah
Published: November 2021

Budidaya hidroponik menggunakan larutan AB Mix masih belum banyak digunakan. Budidaya dengan sistem ini menggunakan tanaman pakcoy membutuhkan konsentrasi tertentu agar tanaman dapat tumbuh dengan baik. Penelitian ini bertujuan untuk: 1) menganalisis nilai TDS dalam larutan AB Mix sebelum diencerkan, 2) menganalisis nilai TDS dalam larutan nutrisi, dan 3) menganalisis tinggi tanaman pakcoy yang ditumbuhkan secara hidroponik menggunakan larutan AB Mix. pada dosis yang berbeda. Rancangan percobaan yang digunakan dalam penelitian ini adalah RAL 1 faktor dengan dosis AB Mix 0 ppm, 5 ppm, 10 ppm dan 15 ppm yang berbeda. Variabel yang diamati adalah nilai TDS pada larutan AB Mix sebelum dan sesudah diencerkan serta tinggi tanaman yang ditumbuhkan menggunakan larutan nutrisi dari AB Mix pada 4 dosis yang berbeda. Perlakukan diulang 3 kali. Hasil penelitian menunjukkan larutan AB Mix sebelum diencerkan memiliki nilai TDS sebesar 6763,67 ppm. Larutan nutrisi dari AB Mix dengan dosis 15 ppm memiliki nilai tertinggi sebesar 1092,67 ppm dan nilai TDS terendah terdapat pada larutan nutrisi dari AB Mix dengan dosis 5 ppm yaitu 503,67 ppm. Sedangkan nilai TDS air yang digunakan sebagai pelarut bahan AB Mix hanya 70 ppm. Tinggi tanaman yang diberi larutan AB Mix menunjukkan pola, semakin tinggi dosis AB Mix dari 0 sampai 15 ppm maka tinggi tanaman semakin tinggi.
Perancangan Prototype Sistem Keamanan Parkir Otomatis Berbasis Radio Frequency Identification (RFID)
Authors: Rosmiati  , Pratama Hidayatullah , Arif Nuraeni
Published: November 2021

Terjadinya kasus kehilangan kendaraan di wilayah kampus khususnya kendaraan roda dua dikarenakan oleh sistem pengawasan keluar masuk kendaraan yang masih menggunakan cara manual. Hal ini dapat mengganggu proses pembelajaran yang berjalan di kampus. Untuk meminimalisir terjadinya pencurian kendaraan dibutuhkan teknologi sistem keamanan parkir  yang bekerja secara otomatis.

Prototype sistem keamanan parkir yang dirancang dalam penelitian ini menggunakan teknologi Radio Frequency Identifacation (RFID) yang terhubung dengan website. RFID ini berfungsi untuk mengidentifikasi pengunjung kampus. Metode identifikasi pada RFID ini menggunakan gelombang radio yang dapat mengirimkan data identitas objek secara nirkabel atau tanpa bantuan manusia.  Prototype ini menggunakan RFID card, RFID reader, Sensor Ultrasonik HRC04, NodeMCU ESP32, Buzzer, Motor Servo, PHP, dan MYSQL.

Hasil dari penelitian ini berupa Prototype sistem keamanan parkir dengan menggunakan teknologi Radio Frequency Identification yang diharapkan dapat membantu petugas keamanan dalam mengawasi keamanan parkir di wilayah kampus.
Spatial suppression due to statistical regularities in a visual detection task
Authors: van Moorselaar Dirk , Theeuwes Jan
Published: November 2021

Increasing evidence demonstrates that observers can learn the likely location of salient singleton distractors during visual search. To date, the reduced attentional capture at high-probability distractor locations has typically been examined using so called compound search, in which by design a target is always present. Here, we explored whether statistical distractor learning can also be observed in a visual detection task, in which participants respond target present if the singleton target is present and respond target absent when the singleton target is absent. If so, this allows us to examine suppression of the location that is likely to contain a distractor both in the presence, but critically also in the absence, of a priority signal generated by the target singleton. In an online variant of the additional singleton paradigm, observers had to indicate whether a unique shape was present or absent, while ignoring a colored singleton, which appeared with a higher probability in one specific location. We show that attentional capture was reduced, but not absent, at high-probability distractor locations, irrespective of whether the display contained a target or not. By contrast, target processing at the high-probability distractor location was selectively impaired on distractor-present displays. Moreover, all suppressive effects were characterized by a gradient such that suppression scaled with the distance to the high-probability distractor location. We conclude that statistical distractor learning can be examined in visual detection tasks, and discuss the implications for attentional suppression due to statistical learning.
Parmenides and the problem of knowing
Authors: Zaitseva Olga
Published: November 2021

This article is based on same-named course work and appears as first part of upcoming research of Ancient Greek Philosophy. The research aim to be a reactivator of social ideas by the way of adopt antique mode of thinking. New method of working at material, trying to represent well-known text in an unusual perspective shows an urgency of this article. Metaphysical poem of Parmenides is taken as a material, so the author prevalently uses a text from the poem and looks at the structure, keywords such as The Truth, necessity, The Fate and Alethea, and a use of them. In the article a correlation between The Truth and necessity, Alethea and The Truth in Parmenides philosophy is explained for the first time. The author pays great attention to Parmenides, so the research has a primary focus on understanding the poem as a Parmenides’ creature. The article has a short biographical background of Parmenides. In this article, the author tries to motivate readers to reflect on it instead of obtruding any defined answers
Analysis of High-precision TESS Photometry of the Black Hole X-Ray Binary Cygnus X-1: Evidence of Intrinsic Variability of the Luminous Blue Supergiant Component
Authors: Petretti Catherine , Guinan Edward
Published: November 2021

We report on Transiting Exoplanet Survey Satellite (TESS) high-precision photometry of the iconic non-eclipsing 5.60 days (O9.7Iab+black hole) binary Cygnus X-1. Previous ground-based photometry reveals low-amplitude (∼0.04 mag) ellipsoidal light-variations that arise from the tidal (and rotational) distortion of the O9.7Iab companion. Additional small light-variations have also been reported by many observers. Short-cadence TESS photometry was conducted over ∼27 days during 2019 July–August. The photometry shows the expected ∼5.60 days binary ellipsoidal variations, but in addition ∼0.01–0.03 mag complex quasi-periodic brightness variations. The observations were analyzed to investigate the underlying extra-binary variability. We also determined a new time of minimum light and calculated an updated period and light elements. The quasi-periodic, (non-binary) light-variations likely arise from the complex pulsations of the blue supergiant.
A new genus from Madagascar with strongly enlarged labium (Ephemeroptera, Baetidae)
Authors: Kaltenbach Thomas , Gattolliat Jean-Luc
Published: November 2021

A new genus of Baetidae, Megalabiopsgen. nov., and a new species, M. madagasikarasp. nov., are described from Madagascar based on nymphs. The new genus is characterized by having a strongly enlarged mentum; pedicelli with many long, stout, pointed setae; a brush of dense, short setae between prostheca and mola of both mandibles; an apically pointed maxillary palp with a stout seta at the tip; and a labium with many long, simple setae ventrally on glossae. The patellotibial suture is absent on the fore tibia and present on middle and hind tibiae. The claw is strongly elongated with two rows of denticles. The imago remains unknown and the relationships with other African genera of Baetidae are tentative. Despite being easily identifiable, only two nymphs were found in two highly sampled localities in Madagascar.
Characterization and analysis of the antidiabetic activities of sulphated polysaccharide extract from Caulerpa lentillifera
Authors: Fajriah Sofa , Rizki Ilmi Fadhilah , Sinurat Ellya
Published: November 2021

Caulerpa lentillifera is a type of green seaweed that is cultivated in tropical and subtropical areas. The objectives of this study were to determine the characteristics of the sulfated polysaccharides from C. lentillifera and evaluate its antidiabetic activity. In the initial process of this study, samples were macerated with ethanol (1:10). Then, the maceration residue was extracted with an accumulator at 75 °C for three hours. The crude extract yield was 4.16% based on weight seaweed. Ion chromatography purification with DEAE-Sepharose resin provided a yield of 14.8% of crude extract. The monomer analysis of C. lentillifera from the crude extract and purified extract revealed that galactose monomers were dominant and glucose was a minor component. The total carbohydrate and sulfate contents of purified C. lentillifera were higher than those of crude C. lentillifera. Bioactivity tests revealed that purified polysaccharides had higher antidiabetic activity against α-glucosidase enzyme than crude ones with IC50 values of 134.81± 2.0 µg/mL. Purified sulfated polysaccharides of C. lentillifera could potentially be used as an antidiabetic medication.
Macular Edema and Serous Macular Detachment after a Standard Dose of Intracameral Cefuroxime
Authors: Davila Jose R. , Mishra Kapil , Leung Loh-Shan
Published: November 2021

Intracameral cefuroxime has been associated with postoperative macular edema and sub-retinal fluid. To date, nearly all published cases are attributed to errors in antibiotic dilution, leading to administration of supratherapeutic doses. We report three cases of postoperative macular edema and subretinal fluid following a standard dose of 1 mg/0.1 mL of cefuroxime at the end of cataract surgery. Distinguishing features of these cases were intraoperative zonular instability and history of vitrectomy. We hypothesize that certain factors may increase the risk of cefuroxime-associated retinal toxicity, including history of vitrectomy, zonular compromise, posterior capsular break, surgery for a secondary intraocular lens, and unicameral state.

[
Ophthalmic Surg Lasers Imaging Retina
. 2021;52:615–618.]
Optimal product release time for a new high-tech startup firm under technical uncertainty
Authors: Wang Ming-hui , Huang Nan-jing , O'Regan Donal
Published: November 2021

Decision makers of new high-tech startup firms always want to choose an optimal time to launch their products which are under research and development (R&D) to obtain the maximum net income of these firms. However, existing models fail to consider the optimal release time of products for these new high-tech startup firms. In this paper, the optimal time to launch the product of the R&D project is assumed to be the first time when the product of the R&D project is released to the market. Based on this assumption, we develop a continuous-time model to find the optimal time at which the startup firm launches its product of the R&D project by considering the price of the similar product. Employing the methods of dynamic programming and variational inequalities, we also provide a closed form solution to our model. We also find that these high-tech startup firms prefer to delay their product release time when the price of the similar product is at a phase of rapid growth or the price has considerable uncertainty. Moreover, some numerical examples are provided to investigate the properties of our model.
A characterization of $ b- $generalized derivations on prime rings with involution
Authors: Raza Mohd Arif ,   Department of Mathematics, College of Science and Arts-Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia, Khan Abdul Nadim , Alhazmi Husain ,   Department of Mathematics, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
Published: November 2021

In this note, we characterize $ b- $generalized derivations which are strong commutative preserving (SCP) on $ \mathscr{R} $. Moreover, we also discuss and characterize $ b- $generalized derivations involving certain $ \ast- $differential/functional identities on rings possessing involution.
Threshold dynamics of a general delayed HIV model with double transmission modes and latent viral infection
Authors: Jiang Xin ,   College of Science, North China University of Technology, Beijing 100144, China
Published: November 2021

In this paper, a general HIV model incorporating intracellular time delay is investigated. Taking the latent virus infection, both virus-to-cell and cell-to-cell transmissions into consideration, the model exhibits threshold dynamics with respect to the basic reproduction number $ \mathfrak{R}_0 $. If $ \mathfrak{R}_0 < 1 $, then there exists a unique infection-free equilibrium $ E_0 $, which is globally asymptotically stable. If $ \mathfrak{R}_0 > 1 $, then there exists $ E_0 $ and a globally asymptotically stable infected equilibrium $ E^* $. When $ \mathfrak{R}_0 = 1 $, $ E_0 $ is linearly neutrally stable and a forward bifurcation takes place without time delay around $ \mathfrak{R}_0 = 1 $. The theoretical results and corresponding numerical simulations show that the existence of latently infected cells and the intracellular time delay have vital effect on the global dynamics of the general virus model.
Los vínculos del ingeniero Pablo Yver Ballester con la industria del gas británica (1902-1944)
Authors: Moyano Jiménez Florentino
Published: November 2021

A principios del siglo XX, el Reino Unido continuaba siendo un referente para la industria del gas europea. Era el país más adecuado para obtener formación, tecnología y equipos. Pablo Yvern sería un ejemplo de estas afirmaciones.
Entre 1902 y 1907, Pablo Yvern Ballester trabajó en la industria británica para completar su formación. Mientras ejerció de ingeniero en la industria del gas española (1907-1944), sus relaciones con la industria británica fueron intensas ya que allí adquirió los equipos más avanzados que necesitaba para sus obras.
La principal aportación tecnológica a la industria del gas española de Pablo Yvern fue la patente que registró en 1911, denominada ‘Perfeccionamiento en los recuperadores de calor para hornos calentados por gas’. Sobre esta patente, fundamentó gran parte de su labor como ingeniero. En ella, hay indicios de la influencia de los conocimientos adquiridos durante su actividad en las empresas británicas Gibbons Juniors y Gibbons Bros Ltd. Su obra como ingeniero significó la mayor reforma y modernización de los elementos de producción, en especial los hornos, realizada en España en el primer tercio del siglo XX.
Un nombre en la torre de marfil. Psicoanálisis y psicología profunda a través de La historia interminable de M. Ende (1979)
Authors: Huertas Maestro Miguel
Published: November 2021

El objetivo del artículo es abordar la relación entre psicoanálisis y arte -en este caso, literatura- entendiendo que este último arrastra intuiciones que posterior o paralelamente hipotetizadas por las disciplinas psi. Para ello, se parte del concepto de “arte visionario” de Carl Gustav Jung y de la noción de que el “artista precede” de Jacques Lacan para explorar la manera en la que una obra como La Historia Interminable (M. Ende) permite arrojar luz sobre los desarrollos teóricos de estos dos autores. En el caso de J. Lacan, los registros de lo simbólico, lo imaginario y lo real. En el caso de C. G. Jung, el viaje interior que supone el proceso de individuación y el contacto con arquetipos del inconsciente colectivo.
Entre la persecución y la instrucción: las comadronas y parteras diplomadas porteñas de inicios del siglo XX
Authors: Paula Lois Ianina
Published: November 2021

El artículo se propone identificar, describir y analizar los discursos y regulaciones en torno a las tareas de las comadronas y parteras impulsados y desarrollados por parte de los médicos de la Ciudad de Buenos Aires de Argentina entre los años que van desde el inicio del siglo XX hasta la década del veinte. En el texto, se da cuenta del proceso de configuración del rol y la profesión de partera desde el punto de vista de los grupos médicos. Se describen las regulaciones y reglamentaciones, y también se hace referencia a los mecanismos de persecución y control de las parteras, en contrapunto con la institucionalización de esta función y su correlato en la creación de espacios de formación. A su vez se describe, desde el discurso médico, la forma en que son presentadas las pretendidas condiciones morales de las parteras de cara a su rol en la educación de las madres.
De las tertulias a la conspiración: la disputa por la belleza y las amistades peligrosas de Alejandro Malaspina en Madrid
Authors: Sánchez Arteaga Juan Manuel
Published: November 2021

Este artículo revisa el periodo transcurrido por Malaspina en Madrid tras su “viaje alrededor del mundo”, hasta su detención en noviembre de 1795. A la luz de fuentes hasta ahora ignoradas por la historiografía malaspiniana, se analiza la participación de Malaspina en una disputa literaria en el Diario de Madrid, donde llegó a publicar bajo seudónimo cuatro cartas filosóficas sobre la belleza que constituyen un antecedente directo de su Meditación filosófica, su obra más personal, escrita en presidio tras su arresto. Por último, se analiza la relación de Malaspina con su vecina madrileña Fernanda O’Connock, marquesa de Matallana, mujer vinculada a la oposición política a Godoy y destacada agente conspiradora contra el primer ministro en dicho periodo, quien muy posiblemente tuvo un papel mucho más activo de lo que hasta ahora se le había reconocido en la conspiración Malaspina.
The Marangoni Convection Effect on Melt Pool Formation during Selective Laser Melting Process
Authors: Aggoune Samia , Hamadi Farida , Kheloufi Karim , Tamsaout Toufik , Amara El-Hachemi , Boughrara Kada , Abid Cherifa
Published: November 2021

In order to predict the effect of the Marangoni convection and the morphology of melted stainless steel powder, during the selective laser melting (SLM) process, a transient three-dimensional numerical model is developed at the mesoscale. The evolution of the temperature and velocity fields’ is then studied. The initial powder bed distribution is obtained by the discrete element method (DEM) calculation, and the temperature distribution and the molten pool shape deformation are calculated and analyzed by the Ansys-Fluent commercial code. The molten pool shape is obtained by considering the influence of Marangoni convection on the internal flow behavior. The recoil force was not considered in our calculation. As main results, a slight deviation between the position of the maximum temperature of the molten pool and the center of the laser spot is observed. The direction of the heat diffusion is more likely to be horizontal and the flow centrifugal, which causes the melt track to be wide. Finally, the Marangoni convection is the main driver of the flow.
Mathematical Modelling of Electrophysical Water Treatment
Authors: Kudryashova Tatiana A. , Polyakov Sergey V. , Tarasov Nikita I.
Published: November 2021

The problem of mathematical modeling the processes of water treatment from charged particles by electric field is considered. The problem is relevant due to the mass use of cleaning technologies in industry, medicine or the national economy. At the present stage, a significant improvement of purification system quality and the introduction of the technologies for the regeneration of their filtration components are required. Mathematical simulation using computer and supercomputer calculations helps to accelerate the development of new devices and cleaning technologies. On the basis of the chosen purification technology, it is important to create a numerical simulation apparatus with a controlled high accuracy of the calculations. For this purpose, we use a quasi-hydrodynamic (QHD) model of a viscous incompressible fluid flow, a system of convection-diffusion equations taking into account the action of the Lorentz force to describe the propagation of harmful impurities in aqueous medium, and an equation for the electric field potential [1, 2]. The numerical algorithm is based on the finite volume method. It is applied in the case of irregular unstructured meshes. This is important for problems of real two-dimensional (2D) and three-dimensional (3D) geometry. Time integration is performed according to an explicit scheme, which simplifies the procedure for parallelizing the algorithm. The proposed approach was tested on the examples of 2D and 3D geometry with various locations of the electrodes and various values of the potentials. The obtained results of the concentration of the ionic impurities show the possibility of this method to purify water from 10 to 40 percent. A design of a water purifier based on electrophysical purification technology can be developed on the base of this study.
Elaboration and Characterization of Cu Based Nanocomposites for Electromagnetic Interferences Shielding
Authors: Kara Farid , Otmane Fadhéla , Bellal Samir , Guerfi Amira Djenet , Triaa S.
Published: November 2021

An electromagnetic interferences (EMI) shielding is a material that attenuates radiated electromagnetic energy. Polymer nanocomposites is a class of materials that combine electrical, thermal, dielectric, magnetic and/ or mechanical properties, which are useful for the suppression of electromagnetic interferences. In this work, we looked over the effectiveness of the electromagnetic interferences shielding of polymer-based nanocomposites. These are thin samples of epoxy resin strengthened with nanostructured Cu powders. Nanostructured Cu powders were obtained by mechanical milling using the high-energy RETSCH PM400 ball mill (200 rpm). A powder sampling was conducted after 3h, 6h, 12h, 24h, 33h, 46h and 58h milling for characterization requirements. XRD analysis via the Williamson-Hall method shows that the mean crystallites size decreases from 151.6 nm (pure Cu phase) to 13.8 nm (58 h milling). Simultaneously, the lattice strain increases from 0.1% (pure Cu phase) to 0.59% (58 h milling). The elaboration of thin samples was performed by mixing a vol./3 fractions of nanostructured Cu powder, epoxy resin and hardener. Thin slabs of 1 mm thickness were moulded for use in a rectangular wave-guide. The EMI shielding experimental involved a two ports S parameters cell measurement made of R120 metallic wave-guides of rectangular section (19.05x9.525 mm2) and operational over the frequency band of 9.84 to 15 GHz associated to a network analyser. Obtained results show moderate EMI shielding effectiveness for the milled Cu-based slabs.
Evaluation of the Environmental Fatigue at a Long Radius Elbow of a Piping System under Transient Thermo Mechanical Stresses
Authors: Ramos-Cantú Lenin , Hernández-Gómez Luis Héctor , García-Illescas Rafael , Arreola-Valles Tanya Nerina , Moctezuma-Reyes José Javier , Carbajal-Figueroa Laura Guadalupe , Armenta-Molina Alejandra , Beltrán-Fernández Juan Alfonso
Published: November 2021

Thermal fatigue widely takes place in light water reactor (LWR) piping systems. It is an important aging mechanism of a nuclear reactor. Thermal transient effects occur at the startup and shutdown of a nuclear power plant. During the thermal transients, local and global cyclic stresses are induced in the piping systems. They are exacerbated by local geometric imperfections and environmental factors, which may lead to crack initiation. The elbows of such piping systems are subject to various combinations of loads (internal pressure, bending, and torsion, as well as thermal fluctuations) during their service life. As can be seen, high-stress concentrations are developed in these piping elements. Therefore, it is important to make a failure evaluation. In this paper, a 12” pipe system segment, which was made with SA 106 Gr C steel, has been considered. It was composed by two straight sections joined by a long radius elbow. Typical start-up and shutdown transient effects of a BWR-5 were considered. A computer-aided thermo-mechanical analysis was carried out using the finite element method. The linearization of the stresses was considered, based on the ASME B & PVC Code Section III, subsection NB. Under these conditions, environmental fatigue was analyzed after 40-and 60-years operation.
Application of the Complex Variable Step Method and the Boundary Element Method for Sensitivity Analysis of Steady Heat Conduction Problems
Authors: Dziatkiewicz Grzegorz , Majchrzak Ewa , Mochnacki Bohdan
Published: November 2021

The paper concerns the problems related to applying the complex variable step method for the sensitivity analysis of the steady temperature field in the solid body domain due to the perturbations of the geometrical and physical parameters. The optimization problem using the approach proposed is also discussed. At the stage of numerical modelling, the boundary element method is used. The first part of the paper is devoted to the shape sensitivity. The results obtained are compared with the solution resulting from the implicit approach of sensitivity analysis.
In the second part, the practical problem concerning optimizing the geometry of continuous casting mould cross-section is considered. The project variable vector contains the cooling pipes' radius and the volume flow rate of the cooling water. The numerical results and the conclusions are presented in the final part of the paper.
CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles
Authors: Phan Hong-Dien , Longjohn Modeline N , Gormley Delania J B , Smith Reilly H , Dang-Lawson May , Matsuuchi Linda , Gold Michael R , Christian Sherri L
Published: November 2021

Extracellular vesicles (EVs) are membrane-encapsulated nanoparticles that carry bioactive cargo, including proteins, lipids, and nucleic acids. Once taken up by target cells, EVs can modify the physiology of the recipient cells. In past studies, we reported that engagement of the glycophosphatidylinositol-anchored receptor CD24 on B lymphocytes (B cells) causes the release of EVs. However, a potential function for these EVs was not clear. Thus, we investigated whether EVs derived from CD24 or IgM-stimulated donor WEHI-231 murine B cells can transfer functional cargo to recipient cells. We employed a model system where donor cells expressing palmitoylated GFP (WEHI-231-GFP) were cocultured, after stimulation, with recipient cells lacking either IgM (WEHI-303 murine B cells) or CD24 (CD24 knockout mouse bone marrow B cells). Uptake of lipid-associated GFP, IgM, or CD24 by labeled recipient cells was analyzed by flow cytometry. We found that stimulation of either CD24 or IgM on the donor cells caused the transfer of lipids, CD24, and IgM to recipient cells. Importantly, we found that the transferred receptors are functional in recipient cells, thus endowing recipient cells with a second BCR or sensitivity to anti-CD24–induced apoptosis. In the case of the BCR, we found that EVs were conclusively involved in this transfer, whereas in the case in the CD24 the involvement of EVs is suggested. Overall, these data show that extracellular signals received by one cell can change the sensitivity of neighboring cells to the same or different stimuli, which may impact B cell development or activation.
Prostate Health Index (phi) and its derivatives predict Gleason score upgrading after radical prostatectomy among patients with low-risk prostate cancer
Authors: Yan Jia-Qi , Huang Da , Huang Jing-Yi , Ruan Xiao-Hao , Lin Xiao-Ling , Fang Zu-Jun , Gao Yi , Jiang Hao-Wen , Wu Yi-Shuo , Na Rong , Xu Dan-Feng
Published: November 2021

To analyze the performance of the Prostate Health Index (phi) and its derivatives for predicting Gleason score (GS) upgrading between prostate biopsy and radical prostatectomy (RP) in the Chinese population, an observational, prospective RP cohort consisting of 351 patients from two medical centers was established from January 2017 to September 2020. Pathological reclassification was determined by the Gleason Grade Group (GG). The area under the receiver operating characteristic curve (AUC) and logistic regression (LR) models were used to evaluate the predictive performance of predictors. In clinically low-risk patients with biopsy GG ≤ 2,phi(odds ratio [OR] = 1.80, 95% confidence interval [95% CI]: 1.14–2.82,P= 0.01) and its derivativephidensity (PHID; OR = 2.34, 95% CI: 1.30–4.20,P= 0.005) were significantly associated with upgrading to GG ≥3 after RP, and the results were confirmed by multivariable analysis. Similar results were observed in patients with biopsy GG of 1 for the prediction of upgrading to RP GG ≥2. Compared to the base model (AUC = 0.59), addition of thephior PHID could provide additional predictive value for GS upgrading in low-risk patients (AUC = 0.69 and 0.71, respectively, bothP< 0.05). In conclusion,phiand PHID could predict GS upgrading after RP in clinically low-risk patients.
An Unusual Complication of Foley Catheterization in a Child
Authors: Kart Yeliz , Bilaloglu Emine , Duman Levent
Published: November 2021

Iatrogenic urethral foreign bodies are rare conditions in clinical practice, and the relevant data are limited to adult cases in the literature. In this paper, we presented a pediatric case in which a fragment of Foley catheter balloon remained in the posterior urethra.
What’s new in molecular genetic pathology 2021: solid tumors and NGS panel selection
Authors: Chen Guoli , Tsang Patricia C.
Published: November 2021

The linchpin of precision medicine is molecular genetic and genomic testing. Molecular biomarkers are important for establishing precise diagnoses and for predicting therapeutic responses that enable cancer patients to receive personalized and targeted treatment. Below are highlights of the current considerations in next generation sequencing (NGS) panel selection, and in molecular testing of solid tumors of the lung, digestive system, thyroid and soft tissue.
Optimizing Network Anomaly Detection Based on Network Traffic
Authors:   Information Assurance dept. FPT University, Hanoi, Vietnam, Son Vu Ngoc
Published: November 2021

Cyber-attack is a very hot topic today. Nowadays, systems must always be connected to the internet, and network infrastructure keeps growing in both scale and complexity. Therefore, the problem of detecting and warning cyber-attacks is now very urgent. To improve the effectiveness of detecting cyber-attacks, many methods and techniques were applied. In this paper, we propose to apply two methods of optimizing cyber-attack detection based on the IDS 2018 dataset using Principal Component Analysis (PCA) and machine learning algorithms. In the experimental section, we compare and evaluate the efficiency of the algorithm through 2 parameters: detection and processing time, and the accuracy of the algorithm. The experimental results show that the model using optimized features has brought an apparent and better effect than models that have not reduced the feature dimension. Keywords— PCA; Network traffic; Anomaly; Cyberattack detection.
Developing a Framework for Detecting Phishing URLs using Machine Learning
Authors:   Information Assurance dept. FPT University, Hanoi, Vietnam, Lam Nguyen Tung
Published: November 2021

The attack technique targeting end-users through phishing URLs is very dangerous nowadays. With this technique, attackers could steal user data or take control of the system, etc. Therefore, early detecting phishing URLs is essential. In this paper, we propose a method to detect phishing URLs based on supervised learning algorithms and abnormal behaviors from URLs. Finally, based on the research results, we build a framework for detecting phishing URLs through endusers. The novelty and advantage of our proposed method are that abnormal behaviors are extracted based on URLs which are monitored and collected directly from attack campaigns instead of using inefficient old datasets. Keywords— phishing URLs; detecting phishing URLs; abnormal behaviors of phishing URLs; Machine learning
Linear Feedback Shift Register and its Applications in Digital System Design
Authors:   Hutech Institute of Engineering, Ho Chi Minh City University of Technology (HUTECH), Vietnam., Nguyen Hai T. , Pham Giao N. , Bui Anh N. , Nguyen Binh A. , Le Ngoc T. , Pham Hanh T.
Published: November 2021

In digital system design, the Linear Feedback Shift Register (LFSR) is the queen of logic functions, and the design engineers can use LFSR in both hardware (HW) or software (SW) implementation. In this paper, LFSR will be discussed in its HW implementation via Hardware description language. In addition, the application of LFSR in of pseudorandom number generator (PRNG), direct sequence spread spectrum (DSSS), cyclic redundancy check (CRC) is also given. Keywords-- Digital system design, System on chip, ASIC digital design, Linear feedback shift register