bluuebunny/crossref_metadata_2025 huggingface dataset:
DEFERRED STENT IMPLANTATION IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND MASSIVE CORONARY THROMBOSIS
Authors: Alekseeva Ya. V. , Vyshlov E. V. , Markov V. A. , Demyanov S. V.
Published: July 2018

By researches it is proved that the phenomenon of no-reflow is an independent predictor of remodeling of the left ventricle at the moment. Particular importance in formation of this phenomenon is the fragmentation of a thrombus with distal embolization of small vessels, which often arise as a complication of the percutaneous coronary intervention during the destruction of a thrombus. Attempts to prevent the development of microvascular obstruction led to the creation of delayed stenting.

The Purpose:assessing the efficacy and safety of deferred stent implantation in patients with ST-segment elevation myocardial infarction and massive coronary thrombosis.

Material and Methods.12 patients with STEMI are included in a research. In the course of emergency coronary angiography was performed a massive thrombosis of the infarct-related coronary artery was observed with TIMI 2–3 blood flow. The emergency stenting wasn’t carried out to these patients, but continued anti-thrombotic therapy within 24 hours. After one day, repeated the coronary angiography was performed and, according to the indications, performed stenting of residual stenosis.

Results.Development of the phenomenon of no-reflow, deaths and coronary events due to reocclusion of the infarctrelated coronary artery at all patients wasn’t observed. Also, all patients had a positive angiographic result in the form of regurgitation of the thrombus as a result of repeated the coronary angiography.

Conclusion.Two-stage revascularization with delayed-on-day stenting with massive thrombosis of the infarct-related coronary artery in patients with acute myocardial infarction combined with aggressive antithrombotic therapy may be use in clinical practice to reduce the risk of developing the no-reflow phenomenon.
Argumentos religiosos y matrimonio igualitario: análisis de las discusiones en el Congreso de la República de Colombia, a la luz de la propuesta de Habermas sobre la religión en la esfera pública
Authors: Aguirre Román Javier Orlando , Pabón Mantilla Ana Patricia , Cáceres Rojas Paul Breinner
Published: July 2018

El presente texto analiza, a la luz de los postulados de la filosofía política de la religión de Habermas, las discusiones desarrolladas en el Congreso de la República de Colombia, en relación con los proyectos de ley que buscaban reglamentar el matrimonio igualitario. La investigación parte de una breve descripción de la propuesta de Habermas y luego aborda el análisis de los argumentos presentados en los debates en el Congreso sobre matrimonio igualitario. Una vez identificadas las fuentes documentales se hace un análisis crítico del discurso, el cual supone una metodología de tipo cualitativo sobre los argumentos presentados en los distintos niveles del debate. El resultado del análisis permitió identificar categorías de argumentos religiosos usados en la discusión política sobre el proyecto de ley analizado, su deficiencia y las dificultades de cumplir con el ideal habermasiano
Creencias de los jóvenes con formación universitaria en la ciudad de Manizales sobre campañas presidenciales entre los años 1998-2010
Authors: Ramírez Marín Juan David , Botero Rendón Maria Del Pilar
Published: July 2018

Esta investigación es de tipo comprensivo; interpreta las creencias de los jóvenes de Manizales con formación universitaria sobre campañas presidenciales entre los años 1998-2010. Dado que los jóvenes son importantes en la democracia de Colombia, se hace necesario conocer sus creencias respecto a las campañas presidenciales y su intención de voto. Esta investigación se desarrolló en cuatro momentos: (i) identificación del problema, (ii) acercamiento a la realidad para recolectar y procesar la información de doce informantes, (iii) representación de las creencias, antecedentes y teoría formal con elementos iconográficos y (iv) interpretación y generación de la propuesta. Los resultados de este estudio permitieron la construcción de una propuesta creativa.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI AUDIT DELAY DAN KETERLAMBATAN PUBLIKASI LAPORAN KEUANGAN PADA PERUSAHAAN CONSUMER GOODS YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: NOVITASARI MAYA
Published: July 2018

This study aims to analyze and find empirical evidence of factors that affect audit delay and delayed publication of financial statements on consumer goods companies listed on the stock exchange Indonesia in 2012-2015. Factors studied in this research are liquidity, profitability, the size of a public accounting firm and auditor opinion as independent variable while audit delay and delayed publication of financial statements as dependent variable. The sample consists of 21 companies listed in Indonesia Stock Exchange selected by using purposive sampling. The analytical tool used is multiple regression analysis to measure audit delay, logistic regression to measure the delay of publication of financial statements and spearman correlation to measure the relationship between audit delay and delayed publication of financial statements. Partial hypothesis test results show that liquidity, profitability, auditor opinion no significant effect on audit delay and publication delay while the size of a public accounting firm there is a significant influence on audit delay and the delay of publication. The correlation result indicates that audit delay has no significant effect on the delay of publication
PEMBELAJARAN AKUNTANSI BERBASIS SPIRITUALITAS, BUDAYA DAN KEARIFAN LOKAL
Authors: ANAS MUHAMAD
Published: July 2018

Penelitian ini bertujuan untuk menganalisis unsur-unsur spiritualitas, budaya dan kearifan lokal dalam rangka membangun sintesis dalam pembelajaran akuntansi. Budaya dan kearifan lokal dalam penelitian ini dibatasi hanya mengacu kepada unsur-unsur budaya dan kearifan lokal dalam budaya Jawa dimana penulis berada dalam lingkungan social dan berintaraksi di dalamnya. Dalam penelitian ini digunakan studi literature dengan pendekatan etnografi, yaitu menemukan unsur-unsur dalam budaya jawa yang merupakan nilai dan diparktikan dalam kehidupan sehari-hari oleh masyarakat Jawa untuk kemudian dijadikan sebagai suatu sintesis dalam pembelajaran akuntansi. Dengan memasukkan unsur-unsur budaya Jawa, yang merupakan kearifan lokal dalam pembelajaran akuntansi, diharapkan peserta didik (baik siswa maupun mahasiswa) memiliki pengetahuan dan wawasan luas serta tidak terlalu kaku dalam memandang akuntansi sebagai disiplin yang multiparadigma, disamping juga pembelajaran akuntansi menjadi menarik dan tidak kering.
AUDIT MANAJEMEN TERHADAP FUNGSI PEMAKAIAN BAHAN BAKU PADA CV. MAJU MAPAN DI TULUNGAGUNG
Authors: Marlena Marlena , Purnomo Ahmad Anton
Published: July 2018

Maju Mapan merupakan perusahaan yang bergerak dibidang produksi perlengkapan peralatan TNI. Penelitian ini bertujuan untuk mengetahui efektifitas terhadap fungsi pemakaian bahan baku. Dan yang menjadi objek penelitian ini adalah bagian pemakaian bahan baku pada CV. Maju Mapan di Tulungagung.

Metode yang digunakan dalam penelitian ini adalah pengujian deskriptif yang merupakan penelitian masalah berupa fakta dari objek penelitian dengan tujuan memberikan gambaran terhadap masalah yang dihadapi, atau mengetahui cara pemecahan masalah.

Teknik analisis data yang digunakan adalah metode kualitatif dan kuantitatif. Dari hasil analisis yang diperoleh menunjukkan selisih perencanaan dan realisasi pada tahun 2016 selisih efektifitas pemakaian bahan baku kain polyester 0.74%, kain puring 0.73%, webbing polyester 0.72%. Tentunya selisih tersebut dapat mengganggu proses produksi sehingga perlu untuk melakukan perbaikan ulang terhadap produk rusak. Maka CV. Maju Mapan perlu melakukan upaya untuk menekan selisih pemakaian bahan baku hingga mendekati 0% sehingga dapat mencapai efektifitas maksimal.

 

Kata Kunci : Audit manajemen, pemakaian bahan baku, efektifitas
Estimates of Noncorporate Private Saving in Pakistan:
1949-1962
Authors: Lewis, Jr. Stephen R. , Khan Mohammad Irshad
Published: July 2018

This paper presents some partial and preliminary estimates of
saving of the noncorporate private sector of the Pakistan economy. It is
a part of a joint effort to make some more detailed estimates of saving
for the entire economy, in which the Institute of Development Economics
has been cooperating. It is hoped that more complete estimates for the
whole economy will be available in the near future, but due to the
importance of saving in the economic develop¬ment policy and planning,
we feel it is worthwhile to present the data and analysis for this
sector. There are estimates of saving in Pakistan for the period 1955/56
to the present, but these have been calculated in a very indirect
manner, and they present no breakdown as to the sources of saving by
sector. The procedure followed in the Planning-Commission estimates in
the Mid-Plan Review1 was to estimate gross investment and to deduct from
gross investment all "deve¬lopment imports" financed from abroad. As has
been pointed out by John H. Power in his evaluation of the Mid-Plan
Review, this method of estimating domestic saving is incorrect2, and he
has presented some adjusted figures for the first two years of the
Second Plan. The Planning-Commission estimation pro¬cedure, even if the
proper definitions are used, is likely to result in serious errors in
the volume of gross saving, and it does not give any information on the
sources of domestic saving.
Import Licensing in Pakistan
Authors: Naqvi Syed Nawab Haider
Published: July 2018

Pakistan's import trade in the private sector is regulated by
an elaborate licensing system. It is complex in its structure and
detailed in its operation. The structural complexity of the system
arises from the simultaneous operation of different types of licences
which seek to regulate the import sector in microscopic detail. It
regulates the volume of imports, the composition of imports, and, in
certain cases, even the sources of imports. This elaborate system is
administered by the Chief Controller of Imports and Exports (CCI&E),
in the Ministry of Commerce, who is the principal licensing authority in
the country. His task is to assess import needs and then to allocate
scarce foreign-exchange resources earmarked for the private sector. In
arriving at his decisions he is guided, on the one hand, by the latest
market intelligence reports regarding the price trends of imported
commodities as the indicators of what the market actually needs, and on
the other hand, by official views of what the market should need, and in
what proportion, to conform to the broader scheme of ensuring an optimal
allocation of domestic resources. The formulation of the semi-annual
Import Policy, which is the sum-total of all these varied and complex
decisions, is, therefore, a momentous undertaking, and occupies a
central position in the broader strategy of economic planning.
Estimation of Nuptiality and its Analysis from the Census Data of
Pakistan
Authors: M. Sadiq Nasim
Published: July 2018

The Muslim Family Laws Ordinance promulgated by the Pakistan
Government in March 1961 requires the registration of all Muslim
marriages with the nominated persons. Such registration is made
practicable by the introduction of the "Basic Democracy" system of
government on the local level. Before the introduction of this system,
there was no all-embracing civil organization for such registration,
though Muslim marriages were generally recorded by the eligious
registrars such as Qazis, Mosque Imams, etc. No private or government
organization ever tried to collect information on marriages from which
age at marriage could be estimated. Data under the new provision are not
yet available; even if available, one cannot immediately measure their
reliability.
Reis e Heróis
Authors: Moura Soares Clara , Neto Maria João
Published: July 2018

O ano de 2016 concentrou a celebração de três efemérides em torno da Igreja de Santa Engrácia - Panteão Nacional: os 180 anos da instituição Panteão Nacional, em 1836; os 100 anos da consagração da inacabada igreja de Santa Engrácia como Panteão Nacional, em 1916; e os 50 anos da conclusão desta igreja e inauguração do Panteão de Heróis Nacionais, em 1966.

O estudo agora apresentado resulta da pesquisa realizada por ocasião da exposição "Reis e Heróis – Os Panteões em Portugal", comemorativa das efemérides referidas, a qual esteve patente ao público no Panteão Nacional, entre 13 de dezembro de 2016 e 7 de maio de 2017. A presente publicação aglutina ainda anteriores trabalhos que as autoras têm vindo a dedicar aos temas dos panteões régios e dos "templos da fama", destinados a homenagear os heróis da Pátria, agora revistos, aumentados e integrados.
Statistika Hospitalitas edisi revisi
Authors: Santosa
Published: July 2018

Puji syukur kehadirat Tuhan Yang Maha Kuasa Allah SWT. Buku Statistika Hospitalitas pada edisi sebelumnya dimanfatkan oleh para pembaca sebagai literatur maupun sebagai referensi untuk kepentingan penyusunan karya ilmiah. Atas dorongan pribadi dan masukan dari para pembaca untuk diterbitkan edisi revisi dengan berbagai perbaikan dan kelengkapan materi maupun redaksi. Pada edisi revisi ini materi buku dilengkapi baik secara toeritis maupun praktis dalam contoh perhitungan baik secara manual maupun melalui program SPSS. Namun demikian penyusun masih sangat mengharapkan masukan dari para pembaca untuk perbaikan berupa kritik, saran atau masukan yang bisa disampaikan melalui alamat e-mail penyusun:santosa_59@yahoo.com.Sesuai dengan judulnya, buku ini memberikan contoh-contoh soal dan kajian tentang statistik yang berorientasi pada masalah-masalah pariwisata, baik bidang perhotelan, destinasi wisata maupun bidang manajemen perjalanan wisata. Untuk kepentingan penyusunan tugas akhir pada program S1, maka buku ini memuat tentang bagian-bagian yang berhubungan dengan metode penelitian yaitu berkaitan dengan uji deskriptif, komparatif, asosiatif maupun prediktif, yang sekaligus diaplikasikan melalui program SPSS untuk memudahkan para pengguna buku ini dalam mengaplikasikan pengujian statistik. Ucapan terimakasih penyusun sampaikan kepada segenap civitas akademika Sekolah Tinggi Pariwisata AMPTA (STP AMPTA) baik secara institusi maupun perorangan yang telah memfasilitasi dan memberikan dorongan sehingga buku ini bisa terwujud. Tak lupa ucapan terimakasih juga penyusun sampaikan kepada istri dan anak-anak tercinta, Uswatun Hasanah S.Pd, M. Arya Wresniwira S.Pd, M.Imawan Badranaya, Ninggih Annisa Daniswara dan Utari Annisa Daniswari atas segala dorongan doa dan moril memberikan kesempatan penyusun untuk berkarya.
GRAPH ISOMORPHISM AND CIRCUIT ISOMORPHISM
Authors: Nguyen Thinh D.
Published: July 2018

In this note, we show that graph isomorphism and some of its variant are both reducible to circuit isomorphism problem, in polynomial time.
Cytochrome allelic variants and clopidogrel metabolismin cardiovascular diseases therapy
Authors: Jarrar Mohammed H
Published: July 2018

Clopidogrel and aspirin are among the most prescribed dual antiplatelet therapies used to treat the acute coronary syndrome (ACS) and heart attacks. However, their potential clinical impacts are a subject of intense debates. The therapeutic efficiency of clopidogrel is controlled by the actions of hepatic cytochrome P450 (CYPs) enzymes and impacted by individual genetic variations. Inter-individual polymorphisms in CYPs enzymes affect the metabolism of clopidogrel into its active metabolites and, therefore, modify its turnover and clinical outcome. So far, clinical trials fail to confirm higher or lower adverse cardiovascular effects in patients treated with combinations of clopidogrel and proton pump inhibitors, compared with clopidogrel alone. Such inconclusive findings may be due to genetic variations in the cytochromes CYP2C19 and CYP3A4/5. To investigate potential interactions/effects of these cytochromes and their allele variants on the treatment of acute coronary syndrome with clopidogrel alone or in combination with proton pump inhibitors, we analyze recent literature and discuss the potential impact of the cytochrome allelic variants on cardiovascular events and stent thrombosis treated with clopidogrel. The diversity of CYP2C19 polymorphisms and prevalence span within various ethnic groups, subpopulations and demographic areas are also debated.
Hubungan praktik hidup psikososial - spritual dengan kebutuhan psikososial spritual pasien sakit terminal, di RSUD Prof Dr. W.Z Johanes Kupang
Authors: Dr.Sabina Gero SKp
Published: July 2018

Kebutuahan psikososial - spritual pasien yang dirawat, kurang disentuh perawat. Hal ini dapat disebabkan karena kedua aspek diri manusia (aspek psikososial dan spritual) tidak berbentuk seperti aspek fisik manusia. Aspek psikososial dan spritual seseorang, terintegrasi dalam seluruh diri manusia dan bentuk dalam tubuhnya (fisik). Dalam kehidupan sehari - hari, aspek psikososial - spritual sering dikesampingkan. Kita lebih memperhatikan tubuh fisik seseorang. Demikian juga pada pasien yang dirawat, perawat cenderung menganggap aspek psikososial - spritual sebagai sesuatu yang pribadi sifatnya, sesuatu area yang tidak bebas disentuh perawat. Ada kesenjangan antar teori keperawatan yang melihat pasien sebagai manusia yang holistik (bio-psiko-sosial dan spritual), dengan praktek keperawatan. Tujuan penelitan ini menganalisis hubungan praktik hidup psikososial-spritual pasien sakit terminal. Metode penelitian yang dipakai dalam penelitian ini cross sectional. Responden adalah pasien dewasa yang dirawat dengan sakit terminal. Sampel diambil dengan teknik accidental, dalam rentan waktu 1 (satu) bulan. Kesimpulan, perawat penting memberikan asuhan keperawatan spritual pada pasien saki terminal. hal ini disebabkan karena sakit kebutuhan spritual pasien terminal meningkat 4 (empat) kali dibandingkan saat sehat. Keyword : Kebutuhan Psikososial, Kebutuhan Spiritual, Sakit Terminal
Keterlibatan Keluarga Dalam Proses Rehabilitasi Anggota Dengan Gangguan Jiwa Di Klinik Rawat Inap Renceng Mose, Ruteng, Kabupaten Manggarai Tahun 2017
Authors: Dr.Sabina Gero SKp
Published: July 2018

Kesehatan jiwa di indonesia belum mendapat penanganan serius (Surya Karya.com,2006), lebih dari 50% penderita gangguan jiwa di negara negara berkembang, termasuk indonesia, belum mendapat pelayanan kesehatan. Data Riskesdas 2013 menunjukan angka rata rata gangguan jiwa berat (ODGJ=Orang Dengan Gangguan Jiwa) sebesar 0,17 % atau sekitar 400.000 orang. Hasil Riskedas 2013, prevalansi gangguan jiwa berat di NTT 1,5/1000 jiwa, masih berada dibawah angka nasional 1,7/1000 jiwa. Orang dengan gangguan jiwa yang pernah dipasung, menurut tempat tinggal di Indonesia, paling tinggi (18,2 %) tinggal di desa, dibandingkan dengan di kota (10,7%), sedangkan angka nasional 14,3%. Pemasungan di NTT besarnya 24,4% yang berarti lebih tinggi dari angka nasional. Rumah sakit khusus (jiwa) di NTT belum beroperasi sampai saat ini. Data dari ruang empati (ruang rawat pasien sakit jiwa) RSUD Prof Dr. W.Z Johanes Kupang, yang ditulis dalam harian Pos Kupang, 20 Juni 2016 menunjukan adanya peningkatan jumlah pasien yang dirawat sejak 2006 - 2015. Pusat Rehabilitasi Penderita Sakit Jiwa Renceng Mose berada di kota Ruteng, Kabupaten Manggarai beridiri sejak tahun 2012, dengan kapasitas 30 tempat tidur. Pusat Rehabilitasi di Renceng Mose menjalani terapi rekreasi, olah raga, spritual (doa, meditasi, ibadat), terapi kerja, aktivitas, komunikasi, refleksi, sharing pengalaman, belajar, imagery, terapy music, sentuhan, warna seni dan humor, terapi belajar dan terapi sentuhan. Berdasarkan hasil penelitian Keterlibatan Keluarga dalam proses Rehabilitasi Anggota dengan Gangguan Jiwa di klinik Rawat Inap Renceng Mose, diperoleh hasil sebagai berikut : terdapat hubungan antara pola komunikasi keluarga dengan kekambuhan dalam proses rehabilitasi anggota keluarga ODGJ di klinik rawat inap Renceng Mose, Ruteng Kabupaten Manggarai pada tahun 2017. Terdapat hubungan antara upaya komunikasi, informasi, edukasi ODGJ kekambuhan dalam proses rehabilitasi anggota keluarga ODGJ di klinik rawat inap Renceng Mose, Ruteng Kabupaten Manggari tahun 2017. Terdapat hubungan antara perkembangan masyarakat dengan kekambuhan dalam proses rehabilitasi anggota keluarga ODGJ di klinik rawat inap Renceng Mose, Ruteng Kabupaten Manggari tahun 2017. Kata kunci : Gangguan Jiwa, Proses Rehabilitasi anggota keluarga ODGJ, Klinik Renceng Mose
Chilamnestocoris mixtus gen. et spec. nov., the first burrower bug (Hemiptera: Pentatomoidea: Cydnidae) in Upper Cretaceous Burmese amber
Authors: Lis Jerzy
Published: July 2018

A new genus and species of burrower bug, Chilamnestocoris mixtus gen. et sp. nov. (Hemiptera: Cydnidae), is described from Upper Cretaceous Myanmar amber. The new genus is characterized by a very long claval commissure and, therefore, is classified within the extant subfamily Amnestinae. It presents a mixture of generic characters relevant to the genus Chilocoris Mayr (Cydninae) and the genus Amnestus Dallas (Amnestinae), but also has its own autapomorphies, i.e., each cephalic marginal setigerous puncture arises from its own well-developed tubercle, and the middle and posterior tibiae are strongly compressed and flattened.
A practical guide to effective behavior change: how to identify what to change in the first place
Authors: Peters Gjalt - Jorn Ygram
Published: July 2018

In this brief accessible introduction, an overview is provided of how to determine which aspects of the target populations' psychology to target in a behavior change intervention. It is the first part of a two-piece introduction to effective behavior change, the second part of which is called "A practical guide to effective behavior change: How to apply theory- and evidence-based behavior change methods in an intervention".
Virtual reality and the new psychophysics
Authors: de Gelder Beatrice , Kätsyri Jari , de Borst Aline W.
Published: July 2018

Virtual reality (VR) promises methodological rigour with the extra benefit of allowing us to study the context-dependent behaviour of individuals in their natural environment. Pan and Hamilton (2018, Br. J. Psychol.) provide a useful overview of methodological recommendations for using VR. Here, we highlight some other aspects of the use of VR. Our first argument is that VR can be useful by virtue of its differences from the normal perceptual environment. That is, by virtue of its relative non-realism and poverty of its perceptual elements, it can actually offer increased clarity with respect to the features of interest for the researcher. Our second argument is that VR exerts its measurable influence more by eliciting an acceptance of the virtual world (i.e., ‘suspension of disbelief’) rather than by eliciting a true belief of the realism of the VR environment. We conclude by providing a novel suggestion for combining neuroimaging methods with embodied VR that relies on the suspension of disbelief.
Development of inhibitory control during childhood and its relations to early temperament and later social anxiety: Unique insights provided by latent growth modeling and signal detection theory
Authors: Troller-Renfree Sonya V. , Buzzell George , Bowers Maureen E. , Salo Virginia , Forman-Alberti Alissa , Smith Elizabeth , Papp Leanna J. , McDermott Jennifer Martin , Pine Daniel , Henderson Heather , Fox Nathan
Published: July 2018

Background: Children with Behavioral Inhibition (BI) temperament face increased social anxiety risk. However, not all children with BI develop anxiety symptoms. Inhibitory control (IC) has been suggested as a moderator of the pathway between BI and social anxiety. The current study uses longitudinal data to characterize development of IC and tests the hypothesis that IC moderates associations between early BI and later social anxiety symptoms. Methods: Children completed a Go/Nogo task at ages 5, 7, and 9 years as part of a longitudinal study of BI (measured at 2-3 years) and social anxiety symptoms (measured at 12 years). To assess IC development, response strategy (criterion) and inhibitory performance (d’) were characterized using signal detection theory. Latent growth models were used to characterize the development of IC and examine relations among BI, IC parameters, and social anxiety symptoms. Results: IC response strategy did not change between 5 and 9 years of age, whereas IC performance improved over time. BI scores in toddlerhood predicted neither initial levels (intercept) nor changes (slope) in IC response strategy or IC performance. However, between ages 5 and 9, rate of change in IC performance, but not response strategy, moderated relations between BI and later parent-reported social anxiety symptoms. Specifically, greater age-related improvements in IC performance predicted higher levels of social anxiety in high BI children.Conclusions: IC development in childhood occurs independent of BI levels. However, rapid IC development moderates risk for social anxiety symptoms in children with BI. Implications for theory and practice are discussed.
The relationship between depressive symptoms, hypomanic symptoms, mood, and category learning.
Authors: Nielsen Emily , Minda John Paul
Published: July 2018

Participants completed several self-assessments that measured depressive symptoms, hypomania, and mood. They were then asked to learn either a set of rule-based categories or a set of non-rule-based categories. Correlational analyses suggested that participants with high levels of self-reported depression were impaired on complex rule learning. In contrast, performance on a rule-based learning task was found to be improved by high levels of current positive mood. Multiple linear regression analyses further revealed that, when the variance due to other constructs was removed, the relationship between depressive symptoms and rule-based performance disappeared while the relationship between positive mood and rule-based performance remained significant. These findings suggest that positive mood is related to enhanced rule learning abilities. Neither level of depression nor positive mood were found to be related to performance on categories that could be learned via associative processes. This dissociation provides evidence for a dual systems approach to categorization. These findings also suggest that executive functioning impairments observed among individuals with depression may be specifically related to a lack of positive mood rather than overall depressive symptoms, per se.
An investigation of the crash performance of magnesium, aluminum and advanced high strength steels and different cross-sections for vehicle thin-walled energy absorbers
Authors: Demirci Emre , Yıldız Ali Rıza
Published: July 2018

In this paper, the effect of conventional steel, new generation DP-TRIP steels, AA7108 – AA7003 aluminum alloys, AM60 – AZ31 magnesium alloys and crash-box cross-sections on crash performance of thin-walled energy absorbers are investigated numerically for the lightweight design of vehicle structures. According to finite element analysis results, crash performance parameters such as total energy absorption, specific energy absorption, reaction forces and crush force efficiencies are compared for the above-mentioned materials. The energy absorption capability of steel energy absorbers is better than that of aluminum and magnesium absorbers. On the other hand, the energy absorption capacity per unit mass of energy absorbers made from lightweight materials is higher than that of steel energy absorbers. This advantage of lightweight alloys encourages automobile manufacturers to use them in designing structural vehicle components.
Model-based correlation between change of electrical resistance and change of dislocation density of fatigued-loaded ICE R7 wheel steel specimens
Authors: Starke Peter , Walther Frank , Eifler Dietmar
Published: July 2018

Weight-optimized component design as well as a reliable estimation of the lifetime of metallic materials and components require a comprehensive understanding of fatigue processes and a systematic investigation of the underlying fatigue behavior. This becomes even more important when designing highly loaded components such as wheels of high-speed passenger railway systems. Typically, mechanical stress-strain hysteresis measurements and increasingly different types of temperature and electrical resistance measurements are used to characterize the fatigue behavior and fatigue processes. Here, electrical resistance measurements provide significant information as they allow the detection of microstructural changes, e. g., through changes in dislocation density and structure. In addition, electrical resistance measurements can be considered in load increase and constant amplitude tests with inserted load-free sequences and in service load tests to characterize damage progress. In this paper, characteristic values of the change in electrical resistance were determined for ICE R7 wheel steel specimens and correlated with dislocation density, which was load- and cycle-dependent and determined through transmission electron microscopy.
Microstructural evolution, phase selection and properties of CoCrCuFeMn
x
Ni high-entropy alloys
Authors: Du Wendong , Liu Ning , Zhou Pengjie , Wang Xiaojing , Wang Bin , Peng Zhen
Published: July 2018

Manganese was added to face-centered-cubic (fcc) high-entropy CoCrCuFeNi alloy to investigate the effects of Mn content on the microstructures, phase selection, and properties of CoCrCuFeMn
x
Ni. CoCrCuFeMn
x
Ni showed typical dendrite and interdendritic structures, and nanoprecipitates including Cu-rich cubic and Cr-rich acicular ones, were obtained in the interdendritic region. Calculated phase-selection-related parameters indicated that the formation of fcc phase was favored. Although two fcc structures were detected by X-ray diffraction, the interdendritic region showed body-centered-cubic, Cr-rich nanoprecipitates when x < 0.5. It is worth noting that the CoCrCuFeMn2.0Ni interdendrites showed an amorphous phase. CoCrCuFeMn
x
Ni showed considerable ductility and increasing compressive strengths with increasing Mn content.
Co3O4/carbon nano-onions composite as supercapacitor electrode and its excellent electrochemical performance
Authors: Wang Chen , Zhu Fuliang , Wang Gongrui , Xiao Mingjun , Meng Yanshuang , Zhang Yue
Published: July 2018

An ionic liquid derived Co3O4/carbon nano-onions composite has been prepared by carbothermal reduction followed by oxidation. The introduction of carbon nano-onions improves the conductivity and structural stability of Co3O4 electrode material. Electrochemical measurements indicate that the redox reversibility is significantly improved. The Co3O4/carbon nano-onions composite shows a large specific capacitance of 402.35 F g–1 at a current density of 0.5 A g–1. After 9000 cycles, the specific capacitance retention remained 76% at 1 A g–1. The as-prepared Co3O4/carbon nano-onions composite delivers superior capacitive performance with good rate capability, large specific capacitance, and excellent cyclic performance, showing great application potential for high-performance electrochemical supercapacitors.
The Purpose of the State: Ancient, Liberal, Marxist and Feminist Standpoints
Authors: Waseem Khan , Sana Hussan , Bushra Qureshi
Published: July 2018

Every political ideology has a distinct conception of various aspects of human life such as reason, purpose of life, free-will, liberty, freedom, autonomy, democracy, sovereignty and moral rights and obligations of the citizen. But the fundamental purpose of a political ideology is to define the purpose of the state and its role in providing a political system to its citizen in which individuals can live their social and political life according to the moral values and ethical principles of that political ideology. This paper only elucidates the purpose of the state according to ancient, Liberal, Marxist and Feminist standpoints. To understand the viewpoint of each political ideology, it is necessary to understand the political thought of its founders. It is pertinent to mention that all political thinkers have one ultimate aim in describing the purpose of the state which is the "ultimate good" of the citizen though they may differ with each other. The viewpoint of one ideology about the purpose of the state may be at odds with another ideology. For example, liberals demand freedom and equality while accepting the capitalist state but Marxist reject the capitalist state in totality, however they also demand freedom and equality of man. Hence, all these political ideologies of these great political thinkers have developed into political movements and later into the formation of political parties which resulted in the modern day civic political system.
Effect of Environmental Enrichment and Herbal Compounds-Supplemented Diet on Pig Carcass, Meat Quality Traits, and Consumers’ Acceptability and Preference
Authors: Casal Nicolau , Font-i-Furnols Maria , Gispert Marina , Manteca Xavier , Fàbrega Emma
Published: July 2018

Animal welfare can be considered an ethical attribute of product quality, but consumers should appreciate its added value. The aim of this study was to evaluate consumer’s acceptability, preference, and the meat and carcass quality of pigs reared with two stress-reducing strategies: supplementation of an herbal compound (HC) containing Valeriana officinalis and Passiflora incarnata, and environmental enrichment (EE) by the provision of hemp ropes, sawdust, and rubber balls. A total of 56 pigs were divided in four treatments in two pens of seven pigs per treatment (2 × 2 factorial design). Meat and carcass quality were evaluated. Consumer’s acceptability and preference were analysed with a sensory test and a conjoint analysis in 110 consumers. Before slaughter, control pigs (no EE and no HC) presented lower live weight compared with other treatments (p = 0.0009). Although acceptance was the same for all of the treatments, consumers preferred systems aiming to increase pig welfare. The most important factor was production system, with a preference for those improving welfare, followed by feeding system, with a preference for those with natural herbs supplementation. Although price was the least important factor, a segment of consumers showed a clear preference for lower prices. These results suggest that welfare improvements could be appreciated by particular consumer segments.
Fatigue Behavior of Prestressed Concrete Beam for Straddle-Type Monorail Tracks
Authors: Pu Qianhui , Wang Hanyu , Gou Hongye , Bao Yi , Yan Meng
Published: July 2018

Monorail transportation systems are widely built in medium and small cities, as well as hilly cities, because of their excellent performance. A prestressed concrete track beam is a key load-carrying structural component and guideway subjected to repeated traffic load. The fatigue behavior of the prestressed concrete beam is critical for the safety of the transportation system. This paper presents the results of an experimental study on the fatigue behavior of a prestressed concrete beam in terms of stiffness degradation and strain change. The displacement and rotation of the beam of concrete and reinforcement were examined, respectively. A three-dimensional finite element model was established to help understand the development of the mechanical behavior. No crack was observed throughout the test. Both concrete and bars behaved in their linear-elastic stage throughout the test, and the bond between them performed well.
Optimization Analysis of the Energy Management Strategy of the New Energy Hybrid 100% Low-Floor Tramcar Using a Genetic Algorithm
Authors: Li Minggao , Li Ming , Han Guopeng , Liu Nan , Zhang Qiumin , Wang Yiou
Published: July 2018

Performance and economic efficiency of the fuel cell (FC)/battery/super capacitor (SC) hybrid 100% low-floor tramcar is mainly determined by its energy management strategy. In this paper, a train traction model was built to calculate the power output and energy consumption properties of the hybrid tramcar. With the purpose of reducing hydrogen consumption, the genetic algorithm was adopted to optimize the original energy management strategy. The results before and after the optimization show that the power requirement of the tramcar can be satisfied in both situations with the fuel cell (FC) module non-stopped. The maximum output power of the FC is reduced from 170 kW to 101.21 kW. As for the SC, a two-parallel connection module is used instead of the three-parallel one, and the power range changes from −125~250 kW to −67~153 kW. Under the original energy management strategy, the battery cannot be used efficiently with less exporting and absorbent power. Its utilization ratio is improved greatly after optimization. In sum, the equivalent total hydrogen consumption is reduced from 3.3469 kg to 2.8354 kg, dropping by more than 15%.
Simulation of Real Defect Geometry and Its Detection Using Passive Magnetic Inspection (PMI) Method
Authors: Mosharafi Milad , Mahbaz SeyedBijan , Dusseault Maurice B.
Published: July 2018

Reinforced concrete is the most commonly used material in urban, road, and industrial structures. Quantifying the condition of the reinforcing steel can help manage the human and financial risks that arise from unexpected reinforced concrete structure functional failure. Also, a quantitative time history of reinforcing steel condition can be used to make decisions on rehabilitation, decommissioning, or replacement. The self-magnetic behavior of ferromagnetic materials is useful for quantitative condition assessment. In this study, a ferromagnetic rebar with artificial defects was scanned by a three-dimensional (3D) laser scanner. The obtained point cloud was imported as a real geometry to a finite element software platform; its self-magnetic behavior was then simulated under the influence of Earth’s magnetic field. The various passive magnetic parameters that can be measured were reviewed for different conditions. Statistical studies showed that 0.76% of the simulation-obtained data of the rebar surface was related to the defect locations. Additionally, acceptable coincidences were confirmed between the magnetic properties from numerical simulation and from experimental outputs, most noticeably at hole locations.
Consuming Production: Anime’s Layers of Transnationality and Dispersal of Agency as Seen in Shirobako and Sakuga-Fan Practices
Authors: Suan Stevie
Published: July 2018

As an alternative reading of anime’s global consumption, this paper will explore the multiple layers of transnationality in anime: how the dispersal of agency in anime production extends to transnational production, and how these elements of anime’s transnationality are engaged with in the transnational consumption of anime. This will be done through an analysis of Shirobako (an anime about making anime), revealing how the series depicts anime production as a constant process of negotiation involving a large number of actors, each having tangible effects on the final product: human actors (directors, animators, and production assistants), the media-mix (publishing houses and manga authors), and the anime media-form itself. Anime production thus operates as a network of actors whose agency is dispersed across a chain of hierarchies, and though unacknowledged by Shirobako, often occurs transnationally, making attribution of a single actor as the agent who addresses Japan (or the world) difficult to sustain. Lastly, I will examine how transnational sakuga-fans tend to focus on anime’s media-form as opposed to “Japaneseness”, practicing an alternative type of consumption that engages with a sense of dispersed agency and the labor involved in animation, even examining non-Japanese animators, and thus anime's multilayered transnationality.
A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance
Authors: Shen Linyuan , Gan Mailin , Tan Zhengdong , Jiang Dongmei , Jiang Yanzhi , Li Mingzhou , Wang Jinyong , Li Xuewei , Zhang Shunhua , Zhu Li
Published: July 2018

tRNA-derived fragments (tRFs) are a new class of non-coding RNA that play an important role in regulating cellular RNA processing and protein translation. However, there is currently no study reporting the influence of tRFs on myocardial hypertrophy. In this study, we used an isoproterenol (ISO)-induced myocardial hypertrophy rat model. Small RNA (<40 nts) transcriptome sequencing was used to select differentially expressed tRFs. We also compared the tRFs expression pattern in F0 sperm and the hearts of F1 offspring between the myocardial hypertrophy group (Hyp) and the control group (Con). Isoproterenol successfully induced a typical cardiac hypertrophy model in our study. Small RNA-seq revealed that tRFs were extremely enriched (84%) in the Hyp heart. Overexpression of tRFs1 and tRFs2 both enlarged the surface area of cardiac cells and increased expression of hypertrophic markers (ANF, BNP, and β-MHC). Luciferase reporter assay identified that tRFs1 directly target 3′UTR of Timp3. tRFs1, tRFs2, tRFs3, and tRFs4 were also highly expressed in Hyp F0 sperm and in Hyp F1 offspring hearts, but there was no differential expression of tRFs7, tRFs9, and tRFs10. Compared to Con F1 offspring, Hyp F1 offspring had elevated expression levels of β-MHC and ANP genes, and they had increased fibrosis and apoptosis in their hearts. These results demonstrated that tRFs are involved in regulating the response of myocardial hypertrophy. Besides, tRFs might serve as novel epigenetic factors that contribute to the intergenerational inheritance of cardiac hypertrophy.
Developments in Cell-Penetrating Peptides as Antiviral Agents and as Vehicles for Delivery of Peptide Nucleic Acid Targeting Hepadnaviral Replication Pathway
Authors: Ndeboko Bénédicte , Hantz Olivier , Lemamy Guy Joseph , Cova Lucyna
Published: July 2018

Alternative therapeutic approaches against chronic hepatitis B virus (HBV) infection need to be urgently developed because current therapies are only virostatic. In this context, cell penetration peptides (CPPs) and their Peptide Nucleic Acids (PNAs) cargoes appear as a promising novel class of biologically active compounds. In this review we summarize different in vitro and in vivo studies, exploring the potential of CPPs as vehicles for intracellular delivery of PNAs targeting hepadnaviral replication. Thus, studies conducted in the duck HBV (DHBV) infection model showed that conjugation of (D-Arg)8 CPP to PNA targeting viral epsilon (ε) were able to efficiently inhibit viral replication in vivo following intravenous administration to ducklings. Unexpectedly, some CPPs, (D-Arg)8 and Decanoyl-(D-Arg)8, alone displayed potent antiviral effect, altering late stages of DHBV and HBV morphogenesis. Such antiviral effects of CPPs may affect the sequence-specificity of CPP-PNA conjugates. By contrast, PNA conjugated to (D-Lys)4 inhibited hepadnaviral replication without compromising sequence specificity. Interestingly, Lactose-modified CPP mediated the delivery of anti-HBV PNA to human hepatoma cells HepaRG, thus improving its antiviral activity. In light of these promising data, we believe that future studies will open new perspectives for translation of CPPs and CPP-PNA based technology to therapy of chronic hepatitis B.
Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings: Clinical Presentation and Management Issues
Authors: Bonaccorso Stefania , Metastasio Antonio , Ricciardi Angelo , Stewart Neil , Jamal Leila , Rujully Naasir-Ud-Dinn , Theleritis Christos , Ferracuti Stefano , Ducci Giuseppe , Schifano Fabrizio
Published: July 2018

Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use. There is limited knowledge regarding the structured assessment and psychometric evaluation of clinical presentations, analytical toxicology and clinical management plans of patients presenting with psychosis and SCRAs misuse. Methods: We gathered information regarding the clinical presentations, toxicology and care plans of patients with psychosis and SCRAs misuse admitted to inpatients services. Clinical presentations were assessed using the PANSS scale. Vital signs data were collected using the National Early Warning Signs tool. Analytic chemistry data were collected using urine drug screening tests for traditional psychoactive substances and NPS. Results: We described the clinical presentation and management plan of four patients with psychosis and misuse of SCRAs. Conclusion: The formulation of an informed clinical management plan requires a structured assessment, identification of the index NPS, pharmacological interventions, increases in nursing observations, changes to leave status and monitoring of the vital signs. The objective from using these interventions is to maintain stable physical health whilst rapidly improving the altered mental state.
Morphomechanical Alterations Induced by Transforming Growth Factor-β1 in Epithelial Breast Cancer Cells
Authors: Cascione Mariafrancesca , De Matteis Valeria , Toma Chiara C. , Leporatti Stefano
Published: July 2018

The Epithelial to mesenchymal transition (EMT) is the process that drives epithelial tumor cells to acquire an invasive phenotype. The role of transforming growth factor-β1 (TGF-β1) in EMT is still debated. We used confocal laser scanning microscopy and scanning force spectroscopy to perform a morphomechanical analysis on epithelial breast cancer cells (MCF-7), comparing them before and after TGF-β1 exogenous stimulation (5 ng/mL for 48 h). After TGF-β1 treatment, loss of cell–cell adherence (mainly due to the reduction of E-cadherin expression of about 24%) and disaggregation of actin cortical fibers were observed in treated MCF-7. In addition, TGF-β1 induced an alteration of MCF-7 nuclei morphology as well as a decrease in the Young’s modulus, owing to a rearrangement that involved the cytoskeletal networks and the nuclear region. These relevant variations in morphological features and mechanical properties, elicited by TGF-β1, suggested an increased capacity of MCF-7 to migrate, which was confirmed by a wound healing assay. By means of our biophysical approach, we highlighted the malignant progression of breast cancer cells induced by TGF-β1 exposure. We are confirming TGF-β1’s role in EMT by means of morphomechanical evidence that could represent a turning point in understanding the molecular mechanisms involved in cancer progression.
PdO/ZnO@mSiO2 Hybrid Nanocatalyst for Reduction of Nitroarenes
Authors: Kim Jinwoo , Kim Aram , Muthuchamy Nallal , Park Kang
Published: July 2018

Development of a novel approach for synthesizing nanostructured catalysts and achieving further improvements in catalytic activity, effectiveness, and efficiency remains a major challenge. In this report, we describe the preparation of a nanostructured PdO/ZnO@mSiO2 hybrid nanocatalyst featuring well-dispersed PdO nanoparticles within hollow ZnO@mSiO2. The as-prepared PdO/ZnO@mSiO2 hybrid nanocatalyst exhibited good morphological features, derived from the controlled stepwise synthesis from Pd/PS@ZIF-8@mSiO2 (PS = polystyrene). The morphology, size, oxidation state, crystallinity, and thermal stability of the prepared PdO/ZnO@mSiO2 hybrid nanocatalyst were confirmed by a series of physicochemical techniques. The PdO/ZnO@mSiO2 hybrid nanocatalyst showed very high catalytic efficiency in the reduction of 4-nitrophenol and various nitroarenes under eco-friendly conditions. Therefore, the PdO/ZnO@mSiO2 hybrid nanocatalyst is a promising alternative catalyst for applications in environmental remediation.