bluuebunny/crossref_metadata_2025 huggingface dataset:
In vivo evaluation of post-operative pain with different NiTi systems after root canal retreatment on single-rooted teeth
Authors:   Department of Conservative Dentistry and Endodontic, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh, India, Priya Swati , K.Varghese Rana , Singh Raunak , Sahu Minakshi , Jaiswal Shreeya , Agrawal Aditee ,   Department of Conservative Dentistry and Endodontic, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh, India
Published: February 2025

The impact of different NiTi systems, such as ProTaper Gold, NeoEndo Flex, Hyflex EDM, Reciproc Blue, and WaveOne Gold, on postoperative pain of single-rooted teeth following root canal retreatment is of interest to dentist. Additionally, the study aims to ascertain whether age, gender, and tooth localization adhering to retreatment with various rotary and reciprocating instruments significantly affect postoperative pain. Root canal re-treatment with 5 (five) distinct rotary or reciprocating NiTi systems did not significantly affect postoperative pain or painkiller consumption. Postoperative pain levels in this trial peaked on the first day and then dramatically declined each subsequent day.
In-vivo analysis of visible light cure calcium hydroxide, mineral trioxide aggregate and platelet-rich fibrin with and without laser therapy for direct pulp capping
Authors:   Department of Conservative Dentistry & Endodontics, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh - 495001, India, Agrawal Aditee , K. Varghese Rana , Gupta Naveen Kumar , Dubey Astha , Priya Swati ,   Department of Conservative Dentistry & Endodontics, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh - 495001, India, Choubey Nishant ,   Department of Oral and Maxillofacial Prosthodontics and Implantology, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh - 495001, India
Published: February 2025

The clinical and radiographic outcomes of direct pulp capping using visible light cure calcium hydroxide, Mineral Trioxide Aggregate, and Platelet-Rich Fibrin, with and without pre-treatment with a low-level diode laser is of interest to dentist. One hundred and twenty patients (18-48 years) with accidental minimal pulp exposures less than 1 mm2 were randomized into two primary groups: laser pre-treatment and no laser pre-treatment, each further divided into three sub-groups based on the capping material. Clinical and radiographic assessments were conducted at 7thday, 1st, 6thand 12th months. The combination of low-level diode laser and mineral trioxide aggregate with platelet-rich fibrin demonstrated superior clinical outcomes compared to other groups. Radiographic analysis showed significant differences in dentin bridge thickness among groups. While all tested materials exhibited promising results, further research is necessary to optimize treatment protocols and ensure long-term clinical success with a specific focus on dentin bridge formation and the potential influence of laser pre-treatment.
Up-cycling the dental waste materials: Going green in dentistry
Authors:   Department of Conservative Dentistry and Endodontics, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattsigarh, India, Khadse Kranti Rajesh , Priya Swati , K. Varghese Rana , Sisodia Malwika , Gupta Naveen Kumar , Chandrakar Anita ,   Department of Conservative Dentistry and Endodontics, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattsigarh, India
Published: February 2025

The depletion of natural resources due to the extensive use of various materials in dentistry is a growing concern. A significant contributor to this issue is the lack of recycling practices, leading to the continuous exploitation of these resources. This research aims to explore simple yet effective scientific techniques to up-cycle common dental materials while maintaining their properties. The focus of modern practices should align with the 3R's-Reduce, Reuse, and Recycle. In dental institutions and clinics, materials like dental plaster and dental stone, extensively used for pouring impressions, are completely discarded as waste. This study involves collecting these waste products and evaluating their properties for potential reuse. Additionally, endodontic materials such as stainless steel hand files and rotary Ni-Ti files, typically discarded, can be recycled in metallurgical departments and repurposed into custom-made cast posts and titanium posts, respectively. The wisdom tooth crush technique is explored for its application as autologous graft material in filling bone defects. Discarded alginate impressions, widely used in Prosthodontics, are heated and repurposed as a denture polishing agent and as a fertilizer in agriculture. Excess glass ionomer cement, a common restorative material, can be repurposed into polishing cones and powders, or used as a polishing agent with rubber cups and buffs. Modeling wax, predominantly used in occlusal rim fabrication, can be collected and purified, with 90% of it recoverable without compromising its properties. Finally, discarded dental burs can be repurposed to splint implant impression copings, aiding in the accurate transfer of orientation, a critical step in implant prosthodontics. This study advocates for the adoption of recycling practices in dental colleges and among practitioners to manage and reuse the waste generated in the field. By doing so, the treatment cost can be reduced by 30-40%, and natural resources can be conserved, contributing to the preservation of the Earth's resources.
Sealing ability of AH Plus endodontic sealer, seal apex, multi-walled carbon nanotube-incorporated AH plus and carbon nanotube-incorporated seal apex using dye penetration microleakage
Authors:   Pacific University of Health Sciences, Udaipur, Rajasthan, India, Saoji Hrishikesh A , Rao Dinesh ,   Department of Pediatric Dentistry, Pacific Dental College, Udaipur, Rajasthan, India, Metgud Sandeep ,   Department of Conservative Dentistry and Endodontics, Pacific Dental College, Udaipur, Rajasthan, India
Published: February 2025

This study evaluates the sealing ability of multi-walled carbon nanotube (MWCNT)-incorporated root canal sealers in the apical third of the root canal. Fifty extracted single-rooted human teeth were divided into five groups: control (no sealer), MWCNT-incorporated AH Plus, MWCNT-incorporated Seal Apex, AH Plus, and Seal Apex. The sealing ability was assessed through dye penetration microleakage. Results indicated that the MWCNT-incorporated sealers exhibited significantly less microleakage compared to traditional sealers, with MWCNT-incorporated AH Plus showing the least leakage. The control group exhibited the highest microleakage. MWCNTs enhanced the sealing efficacy by improving sealer adaptation to the canal walls. These findings highlight the potential of carbon nanotube-enhanced sealers to improve endodontic treatment outcomes. Further studies incorporating in vivo models and longer evaluation periods are recommended to confirm the clinical applicability of these advanced materials.
Effect of various root canal irrigants on bond strength with two obturating systems
Authors:   Department of Conservative Dentistry and Endodontics, Siddhpur Dental College and Hospital, Dethali, Siddhpur - 384151, Gujarat, India, Babulal Patel Hardik Kumar , Kalburge Vaishali Jitendra , Chaudhary Nimisha , Desai Ekta Chaudhari , V. Shah Priyal ,   Department of Conservative Dentistry and Endodontics, Siddhpur Dental College and Hospital, Dethali, Siddhpur - 384151, Gujarat, Indi, Patel Payal ,   Department of Conservative Dentistry and Endodontics, Private Practitioner, Anand Dental Care, Patan - 384265, Gujarat, India, Dash Sindhu Soumya ,   Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India
Published: February 2025

Three-dimensional obturation and careful chemo-mechanical preparation of the root canal system are essential for successful endodontic therapy. The marginal adaption and bond strength of root canal sealers to dentin are critical for the effectiveness of various endodontic operations. Hence, bond strength of Thermo-plasticized Gutta-Percha/ AH Plus sealer and ActiV GP root canal obturation system was compared following EDTA, MTAD, CHX, and Distilled Water used as a final irrigation rinse. The sample consisted of forty extracted teeth which were divided into four groups based on the final irrigation rinse (i.e.,) Group A 3% NaOCl followed by saline and 17% EDTA irrigation as a final rinse, Group B - 3% NaOCl solution followed by saline and MTAD irrigation as a final rinse, Group C - 3% NaOCl solution followed by saline and 2% CHX irrigation as a final rinse, Group D - 3% NaOCl solution followed by saline and distilled water irrigation as a final rinse. Each group was further subdivided based on the obturation system as; thermo-plasticized Gutta-Percha and AH Plus sealer (subgroup 1), and ActiV GP obturation system (subgroup 2). Middle and coronal thirds of every root was cut horizontally with two milli-metres thickness. After that, each slice was examined under a stereomicroscope to measure the diameter of each obturation site and snap photos of each slice's was taken at two sides using a digital camera. Later, an Instron Universal Testing Machine was used to analyze the bond strength of each specimen. CHX- Thermo-plasticized Gutta-Percha /AH Plus (3.654 + 0.056MPa) yielded the maximum average bond strength value. The minimal mean bond strength was noted for distilled water/ActiVGP (1.313 + 0.014 MPa). The other subgroups yielded intermediate bond strength values. Statistically considerable variation was found between subgroup A1 EDTA- Thermo-plasticized Gutta-Percha /AH Plus and subgroup B1 MTAD- Thermo-plasticized Gutta-Percha/AH Plus respectively. It can be found that use of 2% CHX as a final rinse considerably increases the bond strength of both Thermo-plasticized Gutta-Percha/AH Plus and ActiV GP obturation systems.
Finite element analysis of stress allocation for designing different root canal
Authors:   Department of Conservative Dentistry & Endodontics, SCB Dental College & Hospital, Cuttack, Odisha - 753007, India, Mohanty Saumyakanta , Das Abhaya Chandra ,   Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Khandagiri Square, Bhubaneswar - 751030, Odisha, India, Mallick Rashmi Rekha , Sarangi Priyanka ,   Department of Conservative Dentistry & Endodontics, SCB Dental College & Hospital, Cuttack, Odisha - 753007, India, Choudhury Pallabi ,   Lecturer, Government Dental College, Silchar, Srimanta Sankardeva University of Health Science's, Assam, India, Choudhury Purobi ,   Department of Dentistry, Silchar Medical College and Hospital, Attached faculty of Government Dental College, Silchar, Assam, Sahoo Nihar Ranjan ,   Department of Dentistry, MKCG Medical College Berhampur, Odisha - 760004, India, Minz Sneha Arpana ,   Intern, Kalinga Institute Dental Sciences, KIIT, Deemed to be University, Bhubaneswar, Odisha, India
Published: February 2025

It is known that vertical root fractures are influenced by the canal diameter. Therefore, it is of interest to evaluate the stress distribution in three distinct root canal taper designs using finite element analysis. We used a Hyflex Nickel Titanium (NiTi) rotary file to clean and shape a few lower incisor teeth with single canals. Three designs were developed, including a 4% tapered canal preparation, a 6% tapered canal preparation, and an 8% tapered canal preparation. Every tooth sample underwent cone beam computed tomography (CBCT) scans, and any stresses were found using finite element analysis. The collected data was statistically analysed. In all three designs, the coronal area had the most stress, followed by the middle and the apical area with the least. Enamel had a higher stress value than dentin (MPa). In enamel and dentin with either oblique or vertical stress loading, design 3 (8% taper) had the highest stress value, followed by design 2 (6% taper) and design 1 (4% taper). The difference was statistically significant. Enamel had the highest Young modulus value followed by dentin and mandibular alveolar bone, while periodontal ligament (PDL) had the lowest value. In comparison to the apical and middle part, all canal preparations showed greatest enamel stress at the coronal load locations. As canal tapering rises, so does the stress.
Comparison of orthodontic clear aligners and fixed appliances for anterior teeth retraction using finite element analysis
Authors:   MDS, Orthodontist, Private Practitioner, #1085, 2nd Main road, Vivekanada nagar, Mysore-23, Karnataka, India, Thimmaiah Chethan , Tomer Geetika ,   Department of Orthodontics and Dentofacial Orthopedics, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India, Devanna Raghu ,   Reader, Department of Orthodontics, KIMS Dental College and Hospital, KIMS Research Foundation, Amalapuram-533201, East Godavari District, Andra Pradesh, India, Sharma Aseem ,   Department of Orthodontics and Dentofacial Orthopedics, HIDS, Paonta Sahib, Himachal Pradesh, India, Sharma Tanushree ,   Department of Dentistry, Shri Mata Vaishno Devi Institute of Medical Excellence (Medical College & Associated Hospital, SMVDNSH), Kakryal, Jammu and Kashmir, India, Majumdar Antara ,   Intern, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneswar, Odisha, India, Das Abhaya Chandra ,   Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Khandagiri Square, Bhubaneswar - 751030 Odisha, India
Published: February 2025

Orthodontic clear aligners are utilised in order to correct mal-positioned teeth. The comparative effectiveness of transparent aligners and fixed appliance therapy using finite analysis has not been thoroughly studied. Therefore, it is of interest to evaluate the superiority of clear aligners over fixed orthodontic therapy in anterior tooth retraction using finite element analysis (FEA). A maxillary dentition lacking 1stpremolars and with periodontal ligaments was represented by 3D digital models. A transparent aligner, brackets and archwire were produced in a 3D printed lingual retractor. Five distinct models of clear aligners for maxillary anterior internal retraction were designed and created as part of the study: Model M0-Control, Model M1-Posterior Micro-implant, Model M2-Anterior Micro-implant, Model M3-Palatal Plate, Model M4-Enhanced structure, and Model A0- Fixed Appliance. The study result has shown that the crown-root of the central incisor's sagittal displacement varied least in the improved clear aligner Model M 3. Nonetheless, noticeable differences in the patterns of tooth movement were noted between the fixed appliance model and the clear aligner models. The teeth's movement pattern stayed the same in the clear aligner models. Compared to transparent aligner types, the fixed appliance shown greater anterior torque control and improved safety for the posterior anchorage teeth. It has been demonstrated that clear aligners are non-invasive, aesthetically acceptable and effective treatment modality.
Effect of Cocos nucifera oil on tensile strength of two different tissue conditioners at different time intervals
Authors:   Department of Prosthodontics and Crown & Bridge, Hitkarini Dental College and Hospital, Jabalpur, M.P, India, Gupta Pushkar , Pathak Abhishek , Mantri Sneha S ,   Department of Prosthodontics and Crown & Bridge, Hitkarini Dental College and Hospital, Jabalpur, M.P, India, Chansoria Harsh , Solanki Swati ,   Department of Prosthodontics and Crown & Bridge, Government College of Dentistry, Indore, M.P, India, Chansoria Shivakshi ,   Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, M.P, India
Published: February 2025

Tissue conditioners are a short-term soft liner that is frequently used in dentistry to improve the condition of abused denture-bearing tissues, particularly in patients with denture stomatitis. Topical application of antifungal agent has multiple disadvantages which can be negated by incorporation of an herbal agent like Cocos nucifera oil into the tissue conditioner, which can enhance its mechanical properties like tensile strength, while aiding in reduction of C.albicans count in the oral cavity. Therefore, it is of interest to evaluate the tensile strength of Visco-gel and GC soft liner with and without 10% w/w Cocos nucifera oil on different time intervals. 32 dumb-belled shaped samples of each Visco-gel and GC soft liner were divided into two groups of 16 each (with and without 10% w/w Cocos nucifera oil). All the samples were stored in sterile glass jars with distilled water at 37°C. 4 samples from each group were tested for tensile strength on day 1, day 3, day 7 and day 14. Tensile strength test was performed on a Universal testing machine with computer control, data acquisition and data analysis software. Incorporation of 10% w/w Cocos nucifera oil statistically increases the tensile strength of Visco-gel and GC soft liner, from day 1 to day 14, after immersion in distilled water.
Effect of early clinical exposure to GRIT among Indian undergraduate dental students
Authors:   Department of Public Health Dentistry Government Dental College and Hospital, Nagpur, India, Kokane Noopur , Datarkar Abhay ,   Department of Oral Maxillofacial surgery Government Dental College and Hospital Nagpur, India, Khatri Sachin ,   Department of Public Health Dentistry Government Dental College and Hospital, Nagpur, India, Manchanda Jyoti ,   Department of Orthodontics Government Dental College and Hospital, Nagpur, India, Warhekar Shilpa , Dhote Aniket ,   Department of Public Health Dentistry Government Dental College and Hospital, Nagpur, India
Published: February 2025

Dental education is acknowledged for its inherent stressors, demanding a multifaceted skill set from students. Early Clinical Exposure (ECE) has emerged as a potential tool to enhance students' interest and perseverance in the face of challenges. Therefore, it is of interest to explore the influence of ECE on GRIT levels among first-year dental students. GRIT is the combination of passion and perseverance for long-term goals. It reflects an individual's ability to stay committed to their objectives despite challenges or setbacks. Grit is considered a key predictor of success, especially in demanding fields like education, where sustained effort is crucial. A modified 12-item Grit survey was electronically administered to first-year dental students, measuring their perseverance and passion for long-term goals. The study also investigated potential confounding factors such as age, gender and whether dentistry was the first choice for undergraduate studies. The GRIT scale's internal consistency was found to be high (Cronbach's α = 0.88) and test-retest reliability was established (Intra class Correlation Coefficient = 0.98). Data shows a statistically significant positive correlation between early clinical exposure and GRIT levels in first-year dental students. The majority of respondents demonstrated a substantial degree of grit, with 47.5% categorized as "Very Much Gritty." Interestingly, no individuals were classified as "Not Gritty at all." Additional analyses explored the influence of age, gender and dentistry as the first choice on GRIT levels. While no significant impact was observed based on these factors, female students exhibited slightly higher GRIT levels than their male counterparts. This study's findings contribute valuable insights to dental education, emphasizing the potential benefits of integrating ECE into curricula. Dental schools and educators are encouraged to recognize the motivational impact of early clinical exposure, fostering GRIT development among students.
Prevalence of dental caries and oral hygiene among specially-abled children
Authors:   General Dentist, Damascus, Syria, Misrabi Aya , Sharma Dinesh , Sharma Monika ,   Department of Dentistry, Ananta Institute of Medical Sciences and Research Institute, Udaipur, India, Uppal Shaun ,   MpH-D Ontario, Canada, Sadal Mrinalini ,   Private Practitioner, Visakhapatnam, Andhra Pradesh, India
Published: February 2025

Dental caries (tooth decay) is a common oral health problem among children, significantly impacting their overall well-being and quality of life. Therefore, it is of interest to find the prevalence of dental caries and oral hygiene status in specially-abled children. This cross-sectional study was conducted to assess the prevalence of dental caries and oral hygiene status in 225 specially-abled children. The participants, aged <18 years, were included in the study. The study included children with physical, intellectual, and developmental disabilities, ensuring a diverse representation of conditions that may impact oral health. A total of 225 especially abled children participated in the study, with a mean age of 12.5ą 3.4 years. The participants included 130 males (57.8%) and 95 females (42.2%). Children with intellectual disabilities exhibited the highest mean DMFT score (4.2 ą 2.3), with 75% of them affected by dental caries. In comparison, children with physical disabilities had a mean DMFT score of 3.6 ą 1.9 and a caries prevalence of 62%.This study concludes that the prevalence of dental caries and poor oral hygiene status is notably high among specially-abled children, particularly those with intellectual disabilities.
Ultra-sonographic and clinical evaluation of ectopic pregnancy among Indian women
Authors:   Department of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India - 415110, Khan Afroj A. , Patil Supriya , Patange Rajkumar P. ,   Department of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India - 415110
Published: February 2025

The prevalence of ectopic pregnancy, the risk of mortality from ectopic pregnancy has decreased by 90%. Therefore, it is of interest to evaluate role of U/S & clincal aspect in diagnosing ET-PG. 93 patients were assessed by U/S and clinical with various aspect respectively. We found that, for U/S majority patients showed Hemoperitoneum with 73 cases (78.5%) while for clinical aspect majority showed abdominal tenderness with 80 cases (86.0%) respectively. Thus, despite the effective surgical interventions, a few patients experienced post-surgical complications like infection.
Evaluation of long-term stability and relapse rates in open apex teeth following surgical de-rotation and splinting
Authors:   Department of Orthodontics & Dentofacial Orthopaedics, North Bengal Dental College & Hospital, Sushruta Nagar, West Bengal, India, Das Avijit , Pal Kuldeep ,   Oral & Maxillofacial Surgery, Consultant Maxillofacial Surgeon at Pal Hospital, Sagar, Madhya Pradesh, India, Saxena Poorvi ,   Department of Conservative Dentistry and Endodontics, Geetanjali Dental and Research Institute, Udaipur, Rajasthan, India, Parveen SK Naja ,   Department of Paediatric and Preventive Dentistry, Dental College Azamgarh, Ghazipur, Azamgarh, Uttar Pradesh, India, Jaiswal Sachin Kumar ,   Department of Orthodontics & Dentofacial Orthopaedics, Dental College Azamgarh, Ghazipur, Azamgarh, Uttar Pradesh, India, Singh Shalini ,   Department of Pedodontics and Preventive Dentistry, School of Dental Science, Sharda University, Greater Noida, Uttar Pradesh, India
Published: February 2025

The management of open apex teeth requiring surgical intervention poses a significant challenge in dental practice, particularly concerning the long-term stability and potential relapse following treatment. Surgical de-rotation and splinting are common procedures used to correct misalignment in such teeth. This study aims to evaluate the long-term stability and relapse rates in open apex teeth following surgical de-rotation and splinting over a two-year follow-up period. A prospective cohort study was conducted involving 30 patients aged 10-15 years with open apex teeth requiring surgical de-rotation. Each patient underwent surgical de-rotation followed by splinting for a period of six weeks. The patients were monitored at 6 months, 12 months, and 24 months post-treatment. Clinical parameters such as tooth alignment, periodontal health, and any signs of relapse were assessed using radiographic and clinical examination techniques. Data were analyzed using descriptive statistics and the chi-square test to evaluate relapse rates. Out of the 30 patients treated, 28 (93.3%) showed satisfactory alignment and periodontal health at the 6-month follow-up. At 12 months, 26 patients (86.7%) maintained stability, while 4 (13.3%) exhibited minor relapse. By the 24-month follow-up, 22 patients (73.3%) demonstrated long-term stability, while 8 patients (26.7%) experienced relapse. The chi-square test indicated a statistically significant increase in relapse rates over time (p < 0.05). No significant differences were observed in periodontal health between stable and relapsed cases. Surgical de-rotation and splinting of open apex teeth demonstrate a high initial success rate, but relapse rates increase significantly over time. Continuous monitoring and potential adjunctive therapies may be necessary to maintain long-term stability. These findings highlight the importance of patient-specific treatment planning and long-term follow-up in managing open apex teeth.
Awareness, attitudes and cost among patients for dental implants in teeth replacement
Authors:   Adesh Institute of Dental Sciences and Research Centre, General Dentist, Hoshiarpur, Punjab, India, Kaur Maninderjit , Chamakuri Kirithana ,   Government Dental College, General Dentist, Vijayawada, Andhra Pradesh, India, Parashar Pranav ,   Department of Dentistry, N.S.C.B Medical College and Hospital, Jabalpur, M.P, Shah Charmee Hiten ,   AMC Dental College and Hospital, Ahmedabad, Gujarat India, Singh Pargat ,   JCD dental college, General Dentist, Malikpur, Safidon, Jind, Haryana, India, Touchan Layal ,   Aleppo University, Aleppo, Syria
Published: February 2025

Dental implants are increasingly viewed as a preferred treatment option for tooth replacement, yet gaps remain in patient knowledge, attitudes, and cost perceptions. This cross-sectional, in vitro study surveyed 150 adults aged 20-60 to assess their awareness, attitudes, and perceived costs of dental implants. Results show that while 70% of patients are aware of implants, only 30% understand the procedure. Though 60% expressed interest in implants, 45% perceived them as too expensive. Positive attitudes correlated with greater awareness, highlighting the need for enhanced education on the benefits and financial options associated with implants.
Anti-microbial and micro-leakage properties of orthodontic cement
Authors:   Department of Orthodontics and Dentofacial Orthopaedics, School of Dental Sciences, Krishan Vishwa Vidyapeeth (Deemed to be University), Karad, Satara, Maharashtra, India, Wahab Afreen , Ganiger Chanamallappa , Pawar Renuka , Phaphe Sandesh , Ronad Yusuf ,   Department of Orthodontics and Dentofacial Orthopaedics, School of Dental Sciences, Krishan Vishwa Vidyapeeth (Deemed to be University), Karad, Satara, Maharashtra, India
Published: February 2025

Glass Ionomer Cement (GIC) is used for cementing orthodontic bands because of its anti-cariogenic property, which is attributed to the release of fluoride. Therefore, it is of interest to assess the antimicrobial property (AM-P) and micro-leakage (ML) of GIC incorporated with different concentration of N-acetylcysteine (N-AC) & copper nanoparticle (Cu-NP). Our study composed of 5 groups i.e. group I is control with different concentration of N-AC & Cu-NP involving each group with 8 samples. We found that, group V showed the highest ZOI, while the ML was seen highest for group I with a score of 2.2 ą 1.09 and the least score was recorded for Group III (0.8ą 0.37), thus addition of 2% Cu-NP and 15% N-AC resulted in minimal ML. We conclude that increase in concentration of N-AC & CU-NP AM-P efficiency also increases; on the other hand, increase in the concentration of N-AC & Cu-NP did not decrease the ML.
Assessment of symptomatically deviated nasal septum among Indian patients
Authors:   Department of ENT, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India, Patil Harshvardhan Anil , Havle Abhay D. ,   Department of otorhinolaryngology, Krishna Institute of Medical Sciences, Karad - 415 539, Maharashtra, India
Published: February 2025

Nasal Inspiratory Peak Flow (NIPF) is an easy, reliable, inexpensive, and easy-to-measure objective test with a good specificity to measure changes in nasal obstruction on the other hand, sinonasal outcome test-22 (SNOT-22) is questionnaire designed for general health and rhinologic issues. Henceforth, the aim was to evaluate the link between NIPF and SNOT-22 scores before and after surgery. 34 patients underwent clinical & radiological examination followed by questionnaire study before and after the surgery. We found that, no significant change between NIPF & SNOT-22 scores for both age and gender aspect. Thus, pre-op SNOT-22 evaluation can be made a routine exercise as it is equally reliable and highly cost effective as compared to NIPF.
Prediction of pre-eclampsia and eclampsia complications using PIERS
Authors:   Department of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India, Paliwal Esha Jugalkishor , Kshirsagar Nitin S. , Patange Rajkumar P. ,   Department of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India
Published: February 2025

Previous research indicates that Preeclampsia (P-EP) and eclampsia (EP) result in 50,000 maternal deaths annually. The objective was to assess P-EP and EP complications using P-EP integrated estimate of risk score (PIERS). We categorized 60 patients into two groups: group 1, which included 14 patients with Adverse Maternal outcome (AMO), and group 2, which included 46 patients without AMO. They were evaluated using different laboratory investigations and PIERS for adverse feto-maternal outcomes (AFMO). We discovered a significant influence of maternal health conditions on fetal outcomes, with a considerable percentage of newborns needing intensive care and displaying indications of distress immediately after delivery. Consequently, we assert that the results support the incorporation of the PIERS score into standard obstetric care for patients with P-EP and associated conditions.
Effect of oral alpha lipoic acid in treatment of OSMF
Authors:   Department of ENT, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India, Khan AK Shafeem , Kulkarni Vikas ,   Department of ENT, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India, Havle Abhay D. ,   Department of Otorhinolaryngology, Krishna Institute of Medical Sciences, Karad - 415 539, Maharashtra, India
Published: February 2025

Oral submucous fibrosis (OSMF) is a potentially cancerous disorder that affects the oral mucosa and causes a range of symptoms and limitations in function. Assessing the function of oral alpha lipoic acid (AL-A) as a therapy for OSMF is, therefore, intriguing. Fifty patients with OSMF symptoms were evaluated both before and after treatment. They were split into two groups: group A, which served as the control, received 1 ml SI of thioacetamide (TAA) and 1500 IU of hyaluronidase (HYAL) weekly along with the oral antioxidant α-lipoic acid for three months. Group B, which served as the case study, also received 3 months of SI of TAA and HYAL. Patients in group B were recalled for a clinical examination using a vernier caliper (VC), and visual analog scale (VAS) and fibrous bands (FB) were assessed at the 1st, 3rd, and 6th month. We discovered that controls had a comparable distribution pattern across visits when compared to the case. Treatment with AL-A in conjunction with IL-I of TAA and HYAL significantly reduced the severity of symptoms, especially Burning Sensation (BS) and mouth opening (MO), in the case group over time, as previously determined.
Factors affecting failed induction of labour among Indian women
Authors:   Department of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India, Raghoji Vaishnavi S , Patange Rajkumar P , Patil Supriya ,   Department of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Karad - 415110, Maharashtra, India
Published: February 2025

Medical personnel are typically worried when an induction of labour fails. Therefore, it is of interest to evaluate the factors leading to forced internal labor (FIOL). 92 patients were divided into 2 groups namely, group A - filed induction (FI) and group B - successful induction (SI) to collect information with the help of questionnaire, clinical assessment and laboratory findings. We found that, the presence of Oligohydramnios (OGD) does not significantly impact the success of labor induction between the 2 groups. (P = 0.459) Thus, data highlights the importance of considering age, parity, gestational age (GA), Bishop Score and BMI for optimizing labor induction (LI).
Geno-toxic risk assessment of locally produced bovine pericardium (LYOLEMB) for guided tissue regeneration
Authors:   Department of Preventive Dental Science, Faculty of Dentistry, Najran University, Najran, Saudi Arabia, Mohammed Abdulrazzaq Abdo Mohammed , Alanazi Sultan ,   Department of Preventive Dental Science, Faculty of Dentistry, Najran University, Najran, Saudi Arabia, Alyami Ali M. , Alshehri Abdullah Awad , Al Mansour Turki Fahad , AL-Ghwaynim Yazeed Saleh ,   Faculty of Dentistry, Najran University, Najran, Saudi Arabia
Published: February 2025

This study evaluated the genotoxic risk of locally produced bovine pericardium (LYOLEMB) as a guided tissue regeneration (GTR) material for advanced periodontal disease using the Ames test with metabolic activation (a sodium phosphate buffer). Mutagenic effects on Salmonella typhimurium strains TA 98, TA 1537, TA 100, and TA 1535 at concentrations ranging from 0.3125 mg/plate to 5 mg/plate showed no significant genotoxicity, with revertant counts remaining below twice that of the control. Statistical significance was observed near p ≤ 0.05 at certain concentrations, confirming LYOLEMB's non-mutagenic, biocompatible and safe use in periodontal therapy.
An in vitro assessment of push-out bond strength for four types of root canal sealers
Authors:   Department of Conservative Dentistry and Endodontics, Siddhpur Dental College and Hospital, Dethali, Siddhpur-384151, Gujarat, India, Babulal Patel Hardik Kumar , Chaudhary Shaila ,   Department of Pediatrics and Preventive Dentistry, Siddhpur Dental College and Hospital, Dethali, Siddhpur-384151, Gujarat, India, Patel Payal ,   Department of Conservative Dentistry and Endodontics, Private Practitioner, Anand Dental Care, Patan-384265, Gujarat, India, Kubavat Radhika ,   Department of Dentistry and Endodontics, GMERS, Junagadh, India, Kumbhar Sagar ,   epartment of Public Health Dentistry, Government Dental College and Hospital, Chhatrapati Sambhajinagar, Maharashtra, India, Vinod Roshini ,   Department of Oral Pathology and Microbiology, Pandit Deendayal Upadhyay Dental College, Solapur, Maharashtra, India, Jha Stuti ,   Intern, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India
Published: February 2025

A fluid-resistant seal must be created for a root canal (RC) treatment to be successful, and this is typically accomplished by combining gutta-percha with an RC sealer. The push-out bond strength test is used to evaluate the root canal sealer's effectiveness. Therefore, it is of interest to estimate the push out bond strength of dissimilar root canal sealers.40 human premolar teeth were chosen, and after root canal preparation, 10 samples of each of the following sealant materials were used during obturation using gutta-percha cones: Group I: BIO-C ION + sealer; Group II: AH Plus; Group III: Bioceramic sealer (Sure Seal Root); and Group IV: -MTA-Fillapex. After that, the samples were sectioned into coronal, middle, and apical parts by transverse sectioning. A universal testing machine was used to evaluate the push out bond strength (UTM). ANOVA was used to do statistical analysis on the collected data. Compared to the three other sealers, BIO-C ION PLUS sealer's push out bond strength (POBS) was noticeably stronger. The results of this investigation might help clinicians to choose an appropriate endodontic sealer.
Molecular docking and simulation analysis of c-KIT and PDGFRα with phytochemicals as dual inhibitors for GIST
Authors:   Medical Biotechnology Laboratory, Rabat Medical and Pharmacy School, Mohammed V University in Rabat, Rabat, Morocco, El Khattabi Kaoutar
Published: February 2025

Mutations in the c-KIT or PDGFRα genes primarily drive gastrointestinal stromal tumors (GISTs). While tyrosine kinase inhibitors (TKIs) such as Imatinib have improved outcomes, resistance due to secondary mutations remains a significant challenge. This study used computational methods to identify phytochemicals from Moroccan plants as dual inhibitors of c-KIT and PDGFRα. Screening 545 phytochemicals, 6-Hydroxygenistein (6-OHG), a derivative of Genistein, showed high binding affinities (-10.3 kcal/mol for PDGFRα and -10.5 kcal/mol for c-KIT), comparable to Imatinib. 6-OHG demonstrated competitive binding affinities, favorable ADMET properties, good solubility, and oral bioavailability. Its antioxidant properties suggest a potentially lower toxicity profile. Interaction analysis revealed significant hydrogen bonds and hydrophobic interactions with key residues in both targets. Molecular dynamics simulations over 30 ns indicated stable complexes with consistent RMSD values, radius of gyration, solvent-accessible surface area, and hydrogen bonding patterns. Free binding energy calculations using the MM-PBSA method highlighted strong binding efficacy, with total binding energies of -278.0kcal/mol for PDGFRα and -202.1kcal/mol for c-KIT, surpassing Imatinib. These findings suggest that 6-OHG is a promising dual inhibitor for GIST therapy, potentially overcoming resistance mechanisms associated with current TKIs. However, further experimental validation is necessary to fully understand it’s potential.
An anatomico-morphometric analysis of proximal femur
Authors:   Department of Anatomy, Sri Ramachandra Medical College and Research Institute, SRIHER (DU), Porur, Chennai 600 116, Tamil Nadu, India, Bhimsaria Gaurangi , Nagaeswari T. , Srimathi T. , Ramachandran Kalpana ,   Department of Anatomy, Sri Ramachandra Medical College and Research Institute, SRIHER (DU), Porur, Chennai 600 116, Tamil Nadu, India
Published: February 2025

The proximal femur is an important area of interest as it is involved in the articulation of the hip joint and it contributes to the mechanics of locomotion and the weight bearing capacity of the femur. Pathologies like osteoporosis and fractures are common in this site, and surgical interventions like hip arthroplasty and internal fixtures with implants rely on knowledge about the anatomy of the proximal femur to ensure effective treatment. Hence, a greater understanding of these variations will be helpful in constructing better fitted prosthesis. In this study, six morphometric parameters of the proximal femur were studied and measured in 100 dry adult femur bones - head diameter, transverse diameter of fovea, longitudinal diameter of fovea, diameter of neck, intertrochanteric line length, neck shaft angle and correlations were noted. The data obtained is specific for the southern Indian population and hopes to aid in production of better fitted hip prostheses for patients.
Fluoride enigma in end stage renal disease
Authors:   Department of Biochemistry, Sri Devaraj Urs Medical College, Kolar, Tamaka, Karnataka, India, Sharon Rose Paramaturi , Shashidhar Kurpad Nagaraj , Munilakshmi Uppalamethi , Meghanath Muthyala ,   Department of Biochemistry, Sri Devaraj Urs Medical College, Kolar, Tamaka, Karnataka, India
Published: February 2025

Fluoride is an essential micro-mineral. Chronic exposure to fluoride affects collagen biosynthesis, insulin resistance, diabetes mellitus and kidney damage. Present prospective study, include 142 subjects categorised into group I and II. Serum samples was separated and stored appropriately. Statistical significant values were observed in urea, creatinine, calcium, magnesium, fluoride and IL6 in DN. Serum fluoride, total proteins, and calcium showed a positive correlation in group I versus group II. Fluoride is one of the key adjunct and surrogate molecule in causation of micro-vascular complications of diabetes.
El uso de diarios mediáticos como propuesta para promover la alfabetización mediática: caso de estudio sobre el análisis de los hábitos de consumo digital de estudiantes universitarios en España
Authors: Establés María-José , Ruiz-Poveda Cristina
Published: February 2025

Este estudio exploratorio analiza el uso de diarios mediáticos como herramienta para promover la alfabetización mediática entre estudiantes universitarios en España. La investigación se realizó con 134 estudiantes de primer curso del grado en Relaciones Internacionales en una universidad española, empleando el diario mediático como instrumento para examinar sus hábitos de consumo digital y analógico. A lo largo de tres cursos académicos (2019-2020, 2020-2021, 2021-2022), y desde una perspectiva metodológica cualitativa, los estudiantes documentaron su uso mediático durante siete días consecutivos y posteriormente realizaron una reflexión crítica sobre sus patrones de consumo.
El estudio destaca diferencias significativas en las prácticas mediáticas entre los cursos académicos, influenciadas principalmente por las restricciones asociadas a la pandemia de la COVID-19, especialmente en el segundo curso académico, así como por cuestiones de género del estudiantado. Los resultados muestran un predominio del uso de redes sociales y plataformas digitales para fines de entretenimiento, aunque también se evidencia un interés por el consumo informativo en estas redes.
Finalmente, el artículo reflexiona sobre cómo este enfoque metodológico pone de manifiesto la utilidad de los diarios mediáticos en los grados universitarios para promover la educomunicación y fomentar una conciencia más crítica y responsable en el uso de los medios, en un contexto marcado por profundos cambios políticos y tecnológicos.
Conflicto social, liderazgo femenino y comunicación de crisis en Perú: análisis de los discursos presidenciales de Dina Boluarte (2022-2023).
Authors: Moreno Espinosa Dra. Pastora , López-Parra Silvia , Figuereo-Benítez Juan C. , Cartes-Barroso Dr. Manuel J. Cartes-Barroso
Published: February 2025

Este artículo examina las estrategias argumentativas en los discursos políticos de Dina Boluarte, la primera mujer en asumir la Presidencia de la República del Perú, durante su ascenso al poder tras la crisis gubernamental provocada por la destitución del anterior mandatario y en el contexto de las manifestaciones en su contra entre diciembre de 2022 y enero de 2023. Frente a un creciente rechazo popular hacia su gobierno, Boluarte logró mantener una presencia mediática calculada y efectiva, utilizando su liderazgo para consolidar su posición al frente del país. A partir de la Teoría de la Argumentación y el análisis del discurso, el estudio identifica como eje central de su retórica el ataque a las instituciones, incluyendo a la Policía Nacional, las Fuerzas Armadas y los manifestantes opositores, a quienes acusa de estar respaldados por narcotraficantes y terroristas. De esta manera, se puede concluir que Dina Boluarte construye un enemigo común como parte de una estrategia discursiva destinada a consolidar su poder y neutralizar las críticas hacia su liderazgo. Al identificar y etiquetar a ciertos grupos e individuos como amenazas, Boluarte no solo los aísla del debate político legítimo, sino que también busca deslegitimar sus demandas y preocupaciones.
De la radio escolar al podcast educativo
Authors: Revestido Juan Ignacio
Published: February 2025

Este artículo toma para su análisis las seis experiencias de radios escolares que hasta la fecha continúan emitiendo en pueblos de la provincia del Chubut (Argentina). Desde los aportes de la educomunicación, se pone en evidencia cómo la radio puede ser una estrategia didáctica y una mediadora cultural en los procesos de enseñanza y de aprendizaje. Al mismo tiempo, las tecnologías digitales y las nuevas prácticas de consumo entre adolescentes demandan la necesidad de una revisión de las propuestas áulicas y la incorporación de nuevos formatos como el podcast.
Esta investigación tuvo como objetivo caracterizar las estrategias didácticas y comunicacionales que incorporan a procesos educativos los contenidos radiofónicos generados por docentes y estudiantes. A su vez, comparar las características tecno-pedagógicas, sociocomunitarias y comunicacionales entre experiencias de radios escolares y de podcast educativos. La investigación se diseñó con los aportes de la metodología cualitativa a través del estudio de casos para las radios escolares y las técnicas del análisis de contenido de los antecedentes sobre experiencias de podcast educativos en Latinoamérica y España.
Entre los hallazgos, se destacaron las dificultades para la sostenibilidad de estas emisoras escolares y el hecho de que ninguna de ellas ha experimentado el formato podcast con fines educativos. Luego, desde una perspectiva pedagógica sobre los procesos de alfabetización mediática y digital, se evidencian las razones por las cuales es oportuno pasar de este tipo de propuestas de gran envergadura a opciones más accesibles en términos de producción, difusión y consumo a través del podcast educativo.
Alfabetización mediática para la Generación Z desde una perspectiva informativa local: formatos innovadores mediante comunicación inmersiva
Authors: Benitez-Aranda Nerea , Carbonell-Alcocer Alejandro , Gertrudix Manuel
Published: February 2025

La desinformación impacta negativamente en el desarrollo democrático y el progreso social, afectando especialmente a los jóvenes, expuestos principalmente a información local y de proximidad. En un contexto mediático cambiante resulta esencial desarrollar productos educomunicativos específicos que promuevan el pensamiento crítico. El objetivo de esta investigación es desarrollar un producto de comunicación inmersivo, basado en vídeo volumétrico, orientado a mejorar la alfabetización mediática e informacional de la Generación Z en estos entornos. La metodología, basada en un enfoque de Investigación Basada en el Diseño (IBD), explora, mediante el diseño, desarrollo y análisis de un prototipo inmersivo centrado en el sesgo de anclaje, las posibilidades de este tipo de producto para ayudar a los jóvenes a comprender cómo operan los sesgos cognitivos y aumentar su resiliencia frente a la desinformación. Los resultados proponen un plan de producción para el desarrollo ágil de productos inmersivos empleando la tecnología volumétrica, y un entorno virtual que capacite a los jóvenes en técnicas de pre-bunking, especialmente eficaces contra la desinformación de proximidad que circular en contextos locales. Se concluye que las tecnologías inmersivas fortalecen la alfabetización mediática e informacional y la resiliencia de los jóvenes frente a la desinformación.
La embajada española en Londres: Refugio de católicos ingleses. Anne Jay (1586-1661)
Authors: Cagigal Montalbán Ekain
Published: February 2025

La embajada hispánica en Londres ocupó durante el siglo XVII un papel determinante no solo en las relaciones diplomáticas con la monarquía inglesa, sino como foco de referencia y amparo para el catolicismo inglés. Así, fueron numerosos los católicos ingleses que encontraron refugio de mano de la institución española. Con la intención de ilustrar la influencia que los embajadores españoles ejercieron, se presenta en este estudio una semblanza de Anne Jay, como caso paradigmático en el que el destino de una católica inglesa se vio inexorablemente vinculado al desempeño de los embajadores y al propio devenir de la Embajada.