bluuebunny/crossref_metadata_2025 huggingface dataset:
LOCAL HYPOXIA AND IMMUNODEFICIENCY. EFFECT OF OBESITY ON REDUCING THE EFFECTIVENESS OF TREATMENT FOR BACTERIAL VAGINOSIS
Authors: ЖУКЕМБАЕВА А.М. , АКИМЖАН М.К. , АБТЫХАЛИ Н.К. , АЛИМКУЛ И.О. , ДҮЙСЕНБАЙ А.Б. , САТЫБАЛДИЕВА А.К. , МУХАМЕДЖАН А.А. , ТАЛГАТКЫЗЫ Е.
Published: January 2022

Проведен анализ результатов обследования 143 больных бактериальным вагинозом с учетом наличия у них алиментарного ожирения. Все женщины, принимавшие участие в нашем исследовании, дали письменное информированное согласие на участие в нем. Исследование проводили до начала лечения бактериального вагиноза. В зависимости от наличия алиментарного ожирения больных разделили на 2 группы. В I группу вошли 97 с нормальным весом телом, без признаков алиментарного ожирения. Во II группе у 46 больных отмечалось увеличение массы тела, соответствующее алиментарному ожирению II степени. Критериями для анализа являлись результатами бактериоскопического исследования мазков из влагалища, окрашенных по Грамму и выявления в них количественных показателей «ключевых клеток» и показатели оксиметрии, определение интегративного коэффициента Кслиз%, отражающий содержание кислорода в слизистой оболочке, по отношению к показателям, зарегистрированным на II пальце кисти, позволяющего прогнозировать результативность лечения. Таким образом, на фоне алиментарного ожирения еще до начала лечения интенсивность патологического процесса при бактериальном вагинозе была более выражена, чем без него. При этом локальные гипоксия и иммунодефицит свидетельствовали о риске снижения эффективности лечения

The analysis of the results of examination of 143 patients with bacterial vaginosis, taking into account the presence of alimentary obesity, was carried out. All women who took part in our study gave written informed consent to participate in it. The study was carried out before starting treatment for bacterial vaginosis. Depending on the presence of alimentary obesity, the patients were divided into 2 groups. Group I included 97 people with normal body weight, without signs of alimentary obesity. In group II, 46 patients showed an increase in body weight corresponding to alimentary obesity of the II degree. The criteria for the analysis were the results of bacterioscopic examination of vaginal smears stained according to Gram and the identification of quantitative indicators of "key cells" in them and oximetry indicators, determination of the integrative coefficient Cmucous membrane% , reflecting the oxygen content in the mucous membrane, in relation to the indicators recorded on the second finger of the hand, which allows predicting the effectiveness of treatment. Thus, amid alimentary obesity, even before the start of treatment, the intensity of the pathological process with bacterial vaginosis was more pronounced than without it. At the same time, local hypoxia and immunodeficiency indicated the risk of a decrease in the effectiveness of treatment.
ANALYSIS OF PUBLIC AWARENESS OF GENERICS AND THEIR ATTITUDES TOWARD DOMESTIC PHARMACEUTICAL MANUFACTURERS AND REPRODUCED DRUGS/ GENERICS
Authors: ИЗДИБАЙ М.А. , КАНИБАЕВ А.А. , КАБДЫЛКАНОВА Э.Ж.
Published: January 2022

Цель исследования - определить уровень информированности среди населения как по вопросам генериков, так и о фармацевтической промышленности Казахстана. Анкета была разработана с применением системного подхода к её структуре и с соответствующими вопросами, проведён метод онлайн опроса и осуществлена обработка анкет представителей разных сфер деятельности, результаты анкетирования приведены в сравнительном аспекте с использованием диаграмм. При составлении вопросов особое внимание было уделено к вопросам касающихся предпочтений потребителей при выборе страны- производителя, а также их отношение к воспроизведенным препаратам. В публикации затрагивается тема пользы производства генериков по мнению потребителей, а также их личный опыт использования воспроизведенных препаратов. Вопросы были сгруппированы по трем блокам для более структурированного описания ответов: вводные вопросы; опыт применения; Отечественные производители. При формировании вопросов анкеты был соблюден принцип однозначности и краткости

The purpose of the study was to determine the level of awareness among the population on both generics and the pharmaceutical industry in Kazakhstan. The questionnaire was developed using a systematic approach to its structure and with appropriate questions, an online survey method was conducted and questionnaires were processed by representatives of different areas of activity, the results of the survey are given in a comparative aspect with the use of charts. During the preparation of the questions, special attention was paid to the questions concerning the consumers' preferences when choosing the country of manufacture, as well as their attitude towards reproductions. The publication addresses the topic of the benefits of generic production in the opinion of consumers, as well as their personal experience of using reproduced drugs. The questions were grouped into three blocks for a more structured description of the answers: introductory questions; experience of use; and Domestic manufacturers. The principle of unambiguity and brevity was respected in the formation of the questions of the questionnaire.
THE ACTIVITIES OF THE INTERNAL AFFAIRS DIRECTORATE IN EMERGENCIES AS A FACTOR IN THE FORMATION OF PUBLIC OPINION ABOUT THE POLICE
Authors: Тюнь Андрей Петрович
Published: January 2022

В статье рассматриваются основные принципы формирования и трансформации общественного мнения о полиции в гражданской среде, связанные с участием сотрудников правоохранительных органов в мероприятиях, направленных на предотвращение негативных последствий чрезвычайных ситуаций. Рассматриваются объективные риски, возникающие вследствие некорректной трактовки служебных действий сотрудников правоохранительных органов представителями гражданской сферы в условиях ограничения их возможностей с целью минимизации ущерба от чрезвычайной ситуации. Отмечается, что в условиях действия ограничительных мер на период объявления чрезвычайной ситуации усиливается негативное восприятие деятельности сотрудников органов внутренних дел. Оцениваются перспективы, связанные с улучшением социального восприятия полиции в результате освещения самоотверженности и высоких личных качеств сотрудников полиции, с риском для жизни и здоровья участвующих в борьбе с последствиями чрезвычайной ситуации и в спасении гражданского населения. Делается вывод о необходимости использования средств массовой информации как инструмента формирования общественного мнения в целях объективного отражения в общественном сознании россиян профессиональной деятельности работников правоохранительной системы.

The paper examines the principles of the formation and transformation of public opinion about the police in the civilian environment, associated with the participation of law enforcement officers in measures aimed at preventing the negative consequences of emergencies. The publication considers the risks associated with the incorrect interpretation of the official actions of law enforcement officials by representatives of the civilian sphere in the context of limiting their capabilities in order to minimize damage from an emergency. The author evaluates the prospects related to improving the social perception of the police through highlighting the disregard of self and high personal qualities of police officers at risk to life and health of those involved in combating the consequences of an emergency and rescuing the civilian population. It is concluded that the media should be used as an instrument for the formation of public opinion in order to objectively reflect the professional activities of law enforcement officials in the public consciousness of Russians.
SOCIAL STRUCTURE OF ANCIENT RUSSIA
Authors: Искрина Алена Владимировна
Published: January 2022

В статье рассматриваются особенности формирования социальной стратификации Древней Руси на раннем этапе развития, этапы появления различных страт в зависимости от социально-политических событий с X по XII вв. Предметом исследования является процесс образования социальных страт в древнерусском государстве. Цель статьи - рассмотреть социальное устройство Древней Руси, определить и описать стратификацию и взаимодействие страт между собой, историю изучения данного вопроса, политические события, влияющие на данные процессы. Основным вопросом исследования явились исторические события, оказавшие влияние на формирование социальных страт с X по XII вв., появление социальных страт в данный исторический период и формы их взаимодействия. Отвечая на данный вопрос, автор приходит к выводу, что разложение патриархально-общинного строя, формирование феодального вассалитета, принципа майората, княжеской дружины и другие внутриполитические события повлияли на формирование социальных страт государства. В связи с данными историческими событиями удается проследить этапы происхождения социальных слоев населения, их состав, социальные функции в обществе и государстве.

The paper examines the features of the social stratification of the Ancient system at an early stage of development, the stages of the emergence of various strata depending on political events from the 10th to the 12th centuries. The subject of this research is the process of the formation of social strata in the ancient European state. The purpose of the publication is to consider the social structure of Ancient Rus, to determine and describe the stratification and interaction of strata with each other, to study this issue, political events that affect these processes. The main research issue was the historical events that influenced the formation of social strata from the 10th to the 12th centuries, the emergence of social strata in a given historical period and the forms of their interaction. Answering this question, the author arrives at the conclusion that the disintegration of the patriarchal-communal system, the formation of a feudal vassalage, the principle of primacy, the princely squad and other internal political events influenced the formation of social strata of the state. In connection with these historical events, it is possible to trace the stages of the origin of social strata of the population, their composition, social functions in society and the state.
DESIGN AND DEVELOPMENT OF REGENERATIVE DAMPERS
Authors: Singh Aditya , Thakur Manish , shah Akshat , Bajaj Neerake , Taneja Hardik , M/s Promila
Published: January 2022

Each and every automobile in service or being developed in the industry is benchmarked on the basis of its efficiency in running real conditions. So in our project here we have tried to develop a complete new damper and spring setup which can be used in all sorts of suspension systems and in turn provides a feedback loop of voltage which can then be used charge the batteries and upscale the efficiency of bikes by (5-6)% & and for HUV or Sedans by (2-4)% (can even go higher) depending on the terrain. In this setup we harness the mechanical energy into electrical where earlier it was left as heat and vibrational losses. This setup is as cost effective as the earlier dampers where as providing an efficient output in minimal cost increase due to its novelty. The other Features include Electronic height adjustment & on demand suspension softness or stiffness. Keywords: Dampers, Automobile, Electromagnet, EV (Electric vehicle), Voltage, Magnetic flux, Suspension
Application of the E-Bussines Concept to a Double Bread Company (Case Study of FEBI UINSU Students)
Authors: Lbs Arbarija Hafiz , Manurung Erlangga Hakim , Nurbaiti Nurbaiti
Published: January 2022

With the large number of fans of Roti Ganda outside the Pematang Siantar area, therefore an E-business implementation system is needed in the company. The use of e-business technology facilitates company performance and improves company quality. The application of this technology can expand the company's market share, especially the cost for advertising which is cheap compared to advertising on the street and mass media. There needs to be socialization and in-depth  learning as well as careful preparation before implementing e-business applications. In the process of designing the application of E-Business at a web- based Double Bakery Shop with a CRM (Customer Relationship Management) approach, an explanation or theory is needed that can support and support success in making the information system and to explain to users how the functions and benefits of implementing E-Business are needed. on a web-based Double Bakery with a CRM approach.
Alfabetización digital universitaria en estudiantes de ingeniería en tiempos de pandemia
Authors: Palacios Garay Jessica Paola , Fuster Guillen Doris Elida , Rodríguez Barboza Jhonny Richard , Ávila Sánchez Geraldine Amelia , Fernández Díaz Carlos Mario
Published: January 2022

El propósito de este estudio radica en contextualizar la alfabetización digital de los estudiantes universitarios dentro de la actual pandemia, tomando en cuenta el desarrollo de habilidades y retos de esta nueva era digital. Analizar, además, sus alcances y límites para el desarrollo de los estudiantes, quienes siguen con sus estudios profesionales a pesar del confinamiento. Fue un estudio cuantitativo-descriptivo, con variables sociodemográficas (edad, sexo, tiempo de conectividad); la muestra constó de estudiantes de ingeniería de una universidad pública: 213 hombres (64,5 %) y 117 mujeres (35,5 %) del quinto ciclo de carrera. Se utilizó el instrumento de Area (2014). La alfabetización digital y la formación de la ciudadanía del siglo XXI. Concluimos que la alfabetización digital seguirá ampliándose cada vez más, ya que la educación se basa en la virtualidad a causa de la pandemia de covid-19, de modo, que esta modalidad seguirá ampliándose para que los estudiantes continúen con sus estudios superiores con normalidad, desarrollando conocimientos tecnológicos.
Opportunities for development of elevated electric transport in a large city
Authors: Anfilofev Boris A. , Privalov Sergey A. , Kholopov Yury A.
Published: January 2022

Modern large cities include both historically developed central parts and rapidly developing peripheral neighborhoods. Today, transport flows are formed not only by traditional bus, trolleybus, and tram routes, but also by significant fleets of taxis and private vehicles. An increase in traffic load and a shortage of parking spaces significantly reduces the capacity of roads and negatively affects the environmental situation. Ensuring transport accessibility based on the development of underground urban transport, the metro, is accompanied by great labor intensity, time and financial costs. Residents of large cities try to use bicycles, electric scooters, monowheels for intra-city movements. However, in winter in Russia this type of ecological personal transport becomes less accessible. A promising option for the development of public transport for large cities with a significant length of the street network in the absence of the technical possibility of expanding the roadway, can be an elevated electric transport (monorail). Using the example of the city of Samara, where the level of automobilization in 2019 reached 344 cars per 1000 people, the possibilities of developing the transport system of a large city with the inclusion of a monorail transport section in such a system are considered. This innovative solution will improve transport accessibility and reduce the negative impact on the urban environment. The average payback period of the project will be 4.4 years.
Choosing a methodological base for forming and accounting for the construction costs of a gas well at the final stage of field development
Authors: Chejmatova Valery A. , Vaganov Yuriy V.
Published: January 2022

The article introduces the problems of choosing a methodological base for forming and accounting costs during well construction, taking into account the intensification of gas inflow at the final stage of field development. The main methods that allow taking into account the costs of drilling operations are outlined. The main costs that need to be taken into account when designing fields with hard-to-recover gas reserves are identified and characterized. The main stages of cost formation by construction phases of a gas-producing well are shown, as well as the factors influencing the level and structure of the cost price during the construction of a well are highlighted. The authors consider the classification of cost accounting methods in the context of the comparison criterion and present the possible results of the correct choice of the cost formation method during the construction of a gas well at the final stage of its development.
The "freight frame" model as a method of freight transport traffic urban organization
Authors: Haitbaev Valerii A. , Nikischenkov Sergey A.
Published: January 2022

The paper justifies the use of the "freight frame" as a method of organizing the movement of freight vehicle in large metropolitan areas on the example of Samara city district. The study presents the characteristics of the "freight frame" of major European cities, Kazan and Moscow. A comparative analysis of approaches to the organization of the movement of freight vehicle on the basis of the "freight frame" of Russian cities and cities of foreign countries is carried out. Based on the use of the Yandex.Traffic service, an analysis of the congestion of the main transport highways of the city was carried out, a map of the transport accessibility of the city of Samara was compiled with the calculation of the transport accessibility indices of its districts. To analyze the load of freight transport in the Samara region and the city of Samara, the intensity and composition of the traffic of freight transport on the major streets of the city were calculated using the NETVISION Traffic software and hardware complex, differentiated by months and day time. The result of the analysis allowed to identify the most significant problems of traffic management. On the basis of the used methods of freight traffic analysis, the necessity of implementing the "freight frame" model in the city of Samara was justified. A set of sequential measures is proposed to ensure the step-by-step formation of the freight frame model.
Reliability of construction of nuclear power facilities in the global energy market
Authors: Grabovy Pyotr Grigoryevich , Baronin Sergey Aleksandrovich , Berezka Vitaly Viktorovich
Published: January 2022

Purpose: development of conceptual provisions, methodical approaches and practical recommendations about modeling and integrated management at a pre-investment stage of nuclear power construction facilities in the international energy construction market. Materials and methods: a set of the interrelated methodological approaches based on the theory of complex systems life cycle, methods of abstraction, comparison, analysis, synthesis, opposition, modeling, forecasting, expert assessments, risk theory and others. The research is conducted with the use of open data resources of the International Energy Agency (IEA), International Atomic Energy Agency (IAEA), World Nuclear Association (WNA), Nuclear Energy Agency under OECD and ROSATOM State Corporation open statistical data. Results: Features of the modern global world market of nuclear power construction, as well as the role and place of Russia in it, are considered. A comprehensive review of the literature on the studied problems is accomplished. A methodology for modeling the organizational and economic reliability (OER) of complex systems is suggested. Modeling of the structural components of the life cycle (hereinafter LCi-j) of an investment project for the NPP construction on the international market in the conditions of high competition is proposed.
The use of logistics principles in the organization of local work
Authors: Romanova Polina B. , Bondarenko Oksana A. , Mukovnina Natalia A.
Published: January 2022

In the context of growing competition between rail transport and other transport types, there is a need to improve the transportation process. In modern conditions, railway transport is the main link in the logistics chain of moving goods from the shipper to the receiver. The efficiency of the railway transport complex can be improved by using logistics principles in the organization of local work on the network sections. In this study, we suggest ways to solve the problem of improving the quality of service for freight owners and the efficiency of organizing local work, which is relevant for railways. To make decisions aimed at improving the efficiency of the organization of local work, a procedure for determining the costs of organizing and promoting local trains was developed, taking into account the costs on maintaining the railway infrastructure. Not only the operational activity of the railways, but also the quality of transport customers service, compliance with the regulatory deadlines for cargo delivery, depends on the choice of the optimal option for organizing local car traffic into trains and their promotion along the section. The option is selected by comparing the costs for each of the possible options for organizing local car traffic into trains and moving them along the section.
Fuzzy logic methods in assessing the transport and warehouse complexes functioning quality
Authors: Fokeev Anatoly B. , Kononov Ivan I. , Denisov Vladimir V.
Published: January 2022

In most sectors of the national economy, technical facilities are represented by unloading devices that extract bulk cargo from the freight rolling stock, store it for a certain time, and ship it to a similar or other type of transport. Objects intended for the implementation of the stages of loading, unloading, and various storage periods, including bulk cargos, are commonly referred to by the broad scientific community as transport and warehouse complexes (TWC). Most operations performed in the TWC are the movement of goods (internal movements, receiving or sending goods by various modes of transport. The authors clarified the concept of "transport and warehouse complex" - it is an element of the transport network of the region, providing communication of external transport systems of the regions and performing the functions of converting the cargo flow of the region into the cargo flow sent by the region. On the one hand, they perform functions of transshipment points in relation to deep (economic) warehouses, and on the other – the functions of storage facilities. Their primary purpose is determined and depends on a large number of factors, including: the size of the direct service area, the ratio of the design capacity of the warehouse to the volumes of deliveries and the use of bulk cargo, as well as the condition of roads in the serviced area, the uniformity of the receipt of bulk cargo and the availability of vehicles for their delivery to the consumer.
Dados abertos dos Institutos Federais de Educação: análise de temas sugeridos pela Controladoria-Geral da União
Authors: Marques Yuri Bento , Bax Marcello Peixoto , Lopes Júnior Geraldo , Souza Gustavo Henrique Silva de , Melo Eduardo Cardoso
Published: January 2022

Introdução: A abertura das bases de dados governamentais pode contribuir positivamente com a democracia, transparência e controle social, pois oportuniza ao cidadão o acesso, reutilização, modificação e redistribuição livre das informações não sigilosas dos órgãos públicos. Porém, nem todos os dados de interesse da sociedade se encontram publicados em formatos abertos no presente momento. Esse estudo verifica se os dados referentes aos Institutos Federais de Educação, Ciência e Tecnologia, que são comumente solicitados à Controladoria-Geral da União pela sociedade civil, estão sendo catalogados no Portal Brasileiro de Dados Abertos. Método: Foi conduzida uma pesquisa quantitativa no Portal Brasileiro de Dados Abertos com suporte da técnica de pesquisa documental, o que permitiu analisar os conjuntos de dados publicados pelos Institutos Federais. Criou-se um índice para analisar cada um dos 14 temas coletados, o qual originou um indicador quantitativo utilizado na comparação dos resultados de cada Instituto Federal envolvido na pesquisa. Resultados: Identificou-se que 73,70% dos Institutos Federais catalogaram pelo menos um conjunto de dados no Portal Brasileiro de Dados Abertos. No entanto, verificaram-se contundentemente diversas lacunas na disponibilização de dados abertos por parte dessas instituições, além da baixa aderência à abertura de dados em conformidade às recomendações da Controladoria-Geral da União. Conclusão: Estudos como o realizado neste artigo contribuem para que a Administração Pública, especialmente considerando o contexto dos Institutos Federais, tenham subsídios que indiquem possíveis pontos de melhorias no que tange às demandas da sociedade sobre transparência e governança.
OPTIMIZATION OF ULTRASONIC ASSISTED EXTRACTION OF ANTIOXIDANTS FROM MORINGA OLEIFERA LAM. LEAVES USING RESPONSE SURFACE METHODOLOGY
Authors: Sholapur H. N , Dasankoppa F. S , Abbas Z. , Swamy N.G.N. ,   Department of Pharmaceutics, KLE College of Pharmacy, Vidyanagar, Hubballi - 580 031 Karnataka,India
Published: January 2022

The present study was embarked upon for the optimization of conditions aimed at ultrasonic assisted extraction (UAE) of antioxidant chemicals from Moringa oleifera leaves by applying response surface methodology (RSM) based on face centered central composite design (CCD). Evaluation was done at three levels (20 experimental designs) with three process variables: extraction temperature (20, 30, 40oC), extraction time (20, 30, 40 min) and liquid-solid ratio (20:1, 30:1, 40:1) using probe sonicator. The extraction process optimization based on RSM was focused on the capacity of antioxidants present in the extracts to scavenge the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) free radicals. To envisage the optimization process, multiple regression analysis was carried out using RSM tool to obtain a quadratic polynomial equation. Stastical analysis of the factors and their interactions were tested using analysis of variance (ANOVA). Extraction of antioxidants was mainly influenced by liquid-solid ratio and temperature. The ideal combination of variables designed by RSM for maximum radical-scavenging activity was optimized with extracting temperature of 39.80 °C, extracting time of 39.95 min and liquidsolid ratio of 24.00 mL/g to obtain a predicted value of 85.528% of DPPH radical-scavenging activity, which was very close to the experimentally value of 86.49 % with an error of 1.12%, indicating suitability of the model.
CELEBRATING LITHIUM
Authors:   Associate Editor, Indian Drugs, Rao Nagaraj N.
Published: January 2022

Dear Reader, The deluge of information which confronts us daily, coming from traditional sources such as the print media, internet, radio and television and, more recently from various enticing social media, causes us often to miss out important developments or happenings. All of us have to devise an individual strategy to prevent this from occuring too frequently and have to be able to retrieve information fast. The National Institution for Transforming India, better known as NITI Aayog, is currently giving final touches to the medical devices bill, called as the Medical Devices (Safety, Effectiveness and Innovation) Bill, 2019, that will bring a new law to regulate medical devices. Expectedly, consultations with manufacturers, regulators, advocacy groups and associations are contributing significantly to evolving a mature draft Bill.
Aquele que passeia ao teu lado: o fascínio de duplos em Mário de Sá-Carneiro e Richard Weiner
Authors: Špánková Silvie
Published: January 2022

The aim of the present article, based on the comparative method, is to analyse the topic of the double in the work of two authors belonging to literatures that, at first sight, seem to have little in common. The first is Mário de Sá-Carneiro (1890-1916), Portuguese writer and poet, and the second is Richard Weiner (1884-1937), Czech writer, poet and dramatist. The two authors lived in the same period of modernism, in Paris, being influenced by the same artistic and literary sources. In fact, there are some identical, typical modernist proceedings and issues in the work of the two authors (especially, the subjectivism and the identity/alterity problem). In this essay, the common double theme is analysed in the short-stories «Eu-próprio o Outro» (1915) by Sá-Carneiro and «Dvojníci (1916) by Weiner.
Jorge de Sena e o exílio literário espanhol
Authors: Espada Vieira Inês
Published: January 2022

Starting from the concept of exile, in this essay we explore Jorge de Sena as an hispanist. Critic and translator, he had a deep knowledge of Spanish authors and Spanish culture, maintaining regular contact with members of the Spanish intelligentsia in particular in the USA, both at personal level and via letter exchanges.
“Insegne” femminili tra Etruria e Roma
Authors: Bagnasco Gianni Giovanna
Published: January 2022

A partire dalla radice mun-, il contributo ne esplora le differenti traiettorie semantiche in latino e in etrusco che potrebbero portare ad approfondirne il risvolto concreto nelle due culture nel campo delle “insegne” concepite per le donne nelle loro rispettive società. Da un lato le “insegne” morali destinate alle donne latine, tra cui la munditia, e dall’altro quelle concrete etrusche, come gli specchi in funzione catoptromantica. Su uno di questi compare infatti munθuχ, una figura femminile i cui compiti ricadono nella dimensione dell’ordine fisico, naturale e soprannaturale, mantenendosi così il significato più completo della radice mun-.
Short term prediction of atmospheric temperature using neural networks
Authors: PAL S. , DAS J. , SENGUPTA P. , BANERJEE S. K.
Published: January 2022

In this paper, a neural network based forecasting model for the maximum and the minimum temperature for the ground level is proposed. A backpropagation method of gradient-decent learning in multi-layer perceptron (MLP) type of neural network with only one hidden layer is considered. This network consists of 25 input nodes and two output nodes. The network is trained with a varying number of nodes in the hidden layer using a set of training sample and each of them is tested with a set of test sample. It accepts previous two consecutive days information (such as pressures, temperatures, relative humidities, etc.) as inputs for the estimation of the maximum and the minimum temperature as output. The network with 20 or less neurons in the hidden layer is found to be "optimum" and it produces an error within ±2° C for 80% of test cases.
Pengaruh Firm Size, Leverage, Profitabilitas dan Kebijkan Deviden terhadap Manajemen Laba:Studi Kasus Perusahaan Manufaktur yang Terdaftar di BEI Tahun 2016-2019
Authors: Kamalita Dani Irfan
Published: January 2022

Praktik manajemen pendapatan di Indonesia dinilai tinggi karena perlindungan investor yang buruk. Pengelolaan hasil dilakukan oleh para eksekutif dan tim penyus-un neraca karena mereka mengharapkan keuntungan. Tujuan dari penelitian ini adalah untuk secara bersama-sama menganalisis pengaruh ukuran perusahaan, hutang, profitabilitas dan kebijakan dividen. terhadap manajemen laba pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia periode  2016 – 2019. Pengambilan sampel menggunakan teknik unknown sampling yaitu intensional sampling dengan  sampel sebanyak 23 perusahaan dengan masa investigasi 4 tahun Pengujian hipotesis  regresi linier berganda menggunakan metode Program IBM SPSS Statistics versi 23.Hasil penelitian ini menunjukkan bahwa ukuran perusahaan dengan nilai t 0,336 dan tingkat signifikansi 0,038 (<0> 0,05) memiliki pengaruh yang signifikan terhadap manajemen laba. Dengan nilai t-hitung sebesar 0,587, profitabilitas tidak berpengaruh terhadap manajemen laba dan memiliki tingkat signifikansi 0,560 (> 0 0,05). Dengan hitung 0,065 dan  tingkat signifikansi 0,048 (ylt; 0,05), kebijakan dividen berpengaruh signifikan terhadap manajemen laba. Ukuran perusahaan, leverage, profitabilitas dan kebijakan dividen secara keseluruhan berpengaruh signifikan terhadap manajemen laba dengan nilai  signifikansi  0,024 (ylt; 0,05).
Morphometric analysis of middle and posterior cranial fossae foramina in 3D reconstructions of CT images: A midline asymmetry evaluation
Authors: VERIMLI Ural , BUGDAYCI Onur , YILDIZ Sercan Dogukan , OZKILIC Emrah , BEKIROGLU Nural , OZDOGMUS Omer
Published: January 2022

Objective: The cranial base harbours numerous foramina, and the anatomical properties of the foramina are crucial in clinical interventions. The purpose of the current study is to evaluate possible asymmetries regarding the middle and posterior cranial fossae foramina using 3D reconstructions of high-resolution computed tomography (CT) images.
Patients and Methods: High-resolution cranial CT images of 253 female and 287 male adult patients were used in the study. The patients were 18 to 40 years of age without any apparent cranial pathology. The distances from the foramen rotundum, foramen ovale, foramen spinosum, internal acoustic meatus, hypoglossal canal to the midline were measured bilaterally to compare both sides.
Results: The foramen spinosum and the mid-clival line measurements demonstrated statistically significant results favoring the right side (p=0.03, right mean 3.052 ± 0.253 cm, left mean 2.982 ± 0.193 cm). In males, the right foramen spinosum to mid-clival line measurements were significantly longer than the left side (p=0.027, right mean 3.150 ± 0.250 cm, left mean 3.070 ± 0.180 cm).
Conclusion: As predicted, the male measurements were significantly longer than the female measurements regardless of sides in all measurements. The measurements of cranial asymmetries may help describe anomalies and may contribute to the clinical approaches.
Práticas docentes e a inclusão do aluno com paralisia cerebral no contexto escolar
Authors: Adriane Aparecida de Souza Mahl Mangaroti  , Lúcimar dos Santos Alves  , Davino Aquila Florentino  , Rosemeri Theresinha
Published: January 2022

A pesquisa teve como objetivo estudar algumas estratégias específicas de aprendizagem do aluno com paralisia cerebral, com destaque no papel da escola, professor e relação família escola. Foi desenvolvida através de pesquisa bibliográfica mediante leituras, análise e fichamento de livros, periódicos, banco de dados relacionados ao assunto em questão. Verificou-se que os agentes sociais são de suma importância na vida do educando tanto na formação intelectual quanto social. Ressalta-se que, na educação do aluno com PC, não se pode perder de vista a necessidade de garantir o desenvolvimento máximo de suas capacidades, para que ele possa alcançar boa relação com seus pares, bem como o máximo aproveitamento de seu tempo de lazer, de estudo, de forma adaptada e feliz. A criança com PC, como todas as crianças, tem o direito de ter independência, integração e vida social. Sabendo das dificuldades existentes em torno da aprendizagem da pessoa com PC, é importante que o professor esteja apto a buscar a ajuda adequada, zelando pelas particularidades de cada aluno.

 

This research aimed to study some specific learning strategies for students with cerebral palsy, with emphasis on the role of the school, the teacher, and the family-school relationship. It was developed through bibliographic research by reading, analyzing, and annotating books, periodicals, and databases related to the subject in question. It was verified that the social agents are of utmost importance in the life of the student both in the intellectual and social formation. It is noteworthy that, in the education of students with CP, one cannot lose sight of the need to ensure the maximum development of their capabilities, so that they can achieve a good relationship with their peers, as well as the maximum use of their leisure time and study time, in an adapted and happy way. The child with CP, like all children, has the right to independence, integration, and a social life. Knowing the difficulties surrounding the learning of a person with CP, it is important that the teacher be able to seek appropriate help, taking care of each student's particularities.
”Den här kroppen som lämnat mig i sticket”
Authors: Mohlin Åsa , Bernhardsson Katarina
Published: January 2022

”This body that has forsaken me.” Breast cancer, bodies, and recovery in Kristina Sandberg’s "En ensam plats" and Yvonne Hirdman’s "Behandlingen"
This article studies autobiographical accounts of breast cancer, so called pathographies, analysing how the body and the illness are portrayed. The article has a special focus on the experiences of the lived body, relating it to the psychological concept resilience as well as to the sense of estrangement of the body in illness and the socially situated body. The focus of the study is two autobiographical Swedish accounts of breast cancer: Kristina Sandbergs’ En ensam plats (‘A lonely place’, 2021) and Yvonne Hirdman’s Behandlingen. 205 dagar i kräftrike (‘The treatment. 205 days in the kingdom of cancer’, 2019). The article is located in the field of medical humanities and the authors aim to bring out aspects relevant to both the literary understanding of pathographies and the medical understanding of individual experiences of illness.
Virtual Reality Applications in Nursing
Authors: Arslan Gizem , Tokem Yasemin , Isler Yalcin
Published: January 2022

The progress in technological and scientific fields in the 20th century has transformed and shaped the lives of people remarkably. In healthcare, technology can be described as the application of the methods, systems, medicines, devices, vaccines and organized information to improve the quality of life by providing solutions for the needs of both professionals and patients. Besides its potential of reducing fragmentation and costs while increasing the safety, utilization of technology can be considered as the key to achieving a safe, sustainable, and person-centered healthcare environment. Virtual Reality (VR) is a computer-generated three-dimensional interactive environment that stimulates multiple sensory methods. Considering the fact that VR is one of the crucial technological trends of this century, it has the potential of affecting the health industry until 2025 extremely. It is a real-time graphic simulation that includes visual, auditory, and tactile experiences. In the field of health, VR is used for multiple purposes as training of medical students for critical surgeries, education of nursing candidates, and treatment of some diseases. As essential members of the healthcare team, nurses should be a strict follower of the rapidly evolving technology to provide efficient and quality care. The utilization of VR in nursing education has the advantage of decreasing faulty interventions, which enhances patient safety as well as the quality of the healthcare services in the future.
АВІАЦІЙНА ТЕХНІКА ЧЕТВЕРТОГО І П’ЯТОГО ПОКОЛІНЬ: ІСТОРІЯ ТА НАПРЯМИ ПОДАЛЬШОГО РОЗВИТКУ
Authors: Рєзнік Володимир , Постольник Микола , Мосолов Василь , Сторожук Сергій
Published: January 2022

У статті розглядаються процеси виникнення і розвитку бойової авіаційної техніки тактичної авіації четвертого і п’ятого поколінь. Висвітлюються причини, що спонукали її виникнення, характерні риси та відмінності. Розглядаються сильні і слабкі сторони тактичних винищувачів різних поколінь, проводиться їх порівняльний аналіз. Автори зробили висновок про те, що на сьогодні представлені у світі багатофункціональні винищувачі п’ятого покоління не повністю задовольняють потреби військово-повітряних сил як через неповну відповідність тактичним вимогам, так і з економічних міркувань. Визначаються напрями подальшого розвитку авіаційної технічки четвертого покоління, що не вичерпала свій модернізаційний потенціал та спроможна у середньостроковій перспективі відповідати вимогам сучасності. Наприкінці статті висуваються пропозиції щодо можливих напрямів оновлення літакового парку тактичної авіації Повітряних Сил Збройних Сил України.
ОБҐРУНТУВАННЯ УМОВ, ПОТРЕБИ (ДОЦІЛЬНОСТІ) ТА МОЖЛИВОСТІ ЗБІЛЬШЕННЯ (ПРОДОВЖЕННЯ ЗА ТЕХНІЧНИМ СТАНОМ) ВСТАНОВЛЕНОГО РЕСУРСУ ЧУТЛИВИХ ЕЛЕМЕНТІВ АВІАЦІЙНОГО ДВИГУНА АЛ-31Ф
Authors: Бондар Андрій , Шумілін Геннадій , Агамова Раїса
Published: January 2022

У статті наведено аналіз роботи чутливих елементів АЧЭ-240, АЧЭ-202М, АЧМЭС-7, ТЖ-5, АЧЭ-99 авіаційних двигунів типу АЛ-31Ф. Експлуатація та ремонт авіаційних двигунів такого типу та їх вузлів в Україні відбувається за відсутності авторської підтримки з боку розробників і виробників. В процесі ремонту двигунів типу АЛ-31Ф необхідно замінити агрегати з вичерпаним терміном служби на нові. Проведений авторами аналіз роботи чутливих елементів надає можливість збільшення встановленого ресурсу чутливих елементів АЧЭ-240, АЧЭ-202М, АЧМЭС-7, ТЖ-5, АЧЭ-99 при виконанні ремонту на авіаційному ремонтному підприємстві та прийняття обґрунтованого рішення для подальшого застосування їх на авіаційних двигунах типу АЛ-31Ф.
Faktor Penyebab Keterlambatan Pengembalian Dokumen Rekam Medis Rawat Inap
Authors: Sri Sugiarsi  , Rizqy Zumrotus Sholikhah  , Eka Novitayanti
Published: January 2022

Keterlambatan pengembalian dokumen rekam medis rata – rata terjadi pada bagian unit rawat inap. Tujuan penelitian yaitu untuk mengetahui penyebab keterlambatan pengembalian dokumen rekam medis, mengetahui kedisiplinan dokter dan perawat dalam mengisi dan mengembalikan dokumen rekam medis, serta untuk mengetahui dampak yang ditimbulkan dari keterlambatan pengembalian dokumen rekam medis rawat inap. Pertanyaan penelitian ini menggunakan Framewok SPIDER, dan penelitian ini menggunakan desain Literature Review dengan menggunakan database Google Scholar. Hasil penelitian menunjukkan bahwa dokter dan perawat menjadi penyebab utama keterlambatan pengembalian dokumen rekam medis serta kedisiplinan dokter dalam mengisi diagnose penyakit pasien serta tanda tangan pada dokumen rekam medis masih kurang serta kedisiplinan perawat dalam mengembalikan dokumen rekam medis dengan tepat waktu masih kurang, hal tersebut berdampak pada mutu pelayanan rumah sakit terhadap pasien menjadi buruk serta terhambatnya pelaporan mortalitas dan morbiditas rumah sakit. Untuk menghindari keterlambatan pengembalian dokumen rekam medis maka disarankan untuk selalu menekankan SOP (Standart Operating Procedure) tentang batasan waktu pengembalian dokumen rekam medis dengan cara melakukan sosialisasi tertulis maupun lisan kepada seluruh tenaga medis serta mengadakan pelatihan terkait pelayanan yang profesional kepada para petugas medis
Computer-assisted resection of mandibular cancer and repair with fibula free flap. Case report
Authors:   Department of Oral and Maxillofacial Surgery, 424 General Military Hospital of Thessaloniki (Head: Dr. Christos Magopoulos), CHATZISTEFANOU Ioannis , Tilaveridis Ioannis , Banikas Vasileios , Deligiannidis Dimitris , Saramantos Antonios , Dimakou Mariam , Kouridakis Petros , Michailidis Apostolos , Gkouvas Georgios , Magopoulos Christos
Published: January 2022

Oral cancer is a disease, in the treatment of which the surgical resection of the lesion plays a lead- ing role. Oncological resections in the maxillofacial area create large deficits that affect the functionality and aesthetics of the patient to a large extent, while many times make oncological resection impossible due to their inability to restore. The mandibular deficits are particularly difficult, with the free osteocutaneous fibular flap being the gold standard in repairing large mandibular deficits. In recent years, technology has offered significant as- sistance in the successful restoration of functional and aesthetic disorders through the virtual planning of the operation. In this paper we present a case of oral cancer whose resection and reconstruction with fibula free flap were done after digital design and under the guidance of special cutting guides. To our knowledge, this case of computer-guided reconstruction with FFF represents the first description of such a technique for mandibular reconstruction in the available greek medico-dental literature.
Expect the unexpected – A rare case of Orthokeratinized Odontogenic Cyst and its surgical management
Authors:   MSM hospitals, No.25B/70 Thilagar Street, Adirampattinam-614701, Thanjavur District, Tamilnadu, India, Sameerudeen M.M. Sheik , Mugundan R.N. , Shwetha S , Fahmidha A.
Published: January 2022

Orthokeratinized Odontogenic Cyst (OOC) is a rare, developmental odontogenic cyst of the dental lamina. It was initially defined as the uncommon orthokeratinized variant of the Odontogenic Keratocyst (OKC), until the World Health Organization’s (WHO’s) classification in 2005 and 2017, where it was separated from the Keratocystic Odontogenic Tumor (KCOT) and has been included as a separate entity from the category of developmental odontogenic cysts respectively. It presents as a unilocular radiolucent lesion involving the posterior mandible and is frequently related to impacted teeth, often similar to other odontogenic cysts. Due to low local aggressiveness and less proliferative activity, it has to be differentiated from the other cysts in terms of surgical management. Here we report a rare case of OOC involving the maxilla along with an impacted canine and discuss the surgical management and why a secondary surgical intervention is unnecessary.
Pengaruh Ukuran Perusahaan, Profitabilitas, Leverage, Dan Kualitas Audit Terhadap Penghindaran Pajak Pada Perusahaan Manufaktur Periode 2016-2018
Authors: Tagor Darius Sidauruk  , Siti Nur Fadilah
Published: January 2022

Perusahaan berusaha menekan biaya pajaknya demi mendapatkan laba yang lebih tinggi. Terdapat beberapa faktor yang mempengaruhi penghindaran pajak dalam suatu perusahaan. Penelitian ini bertujuan untuk mengetahui apakah ukuran perusahaan, profitabilitas, leverage, dan kualitas audit berpengaruh terhadap penghindaran pajak.

Populasi penelitian ini adalah perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) pada tahun 2016-2018 yaitu sebanyak 153 perusahaan. Sampel penelitian berjumlah 72 perusahaan atau 216 data observasi yang dipilih dengan metode purposive sampling. Data yang dipergunakan adalah data sekunder yang diperoleh dari Bursa Efek Indonesia (BEI).  Metode analisis data dalam penelitian ini yaitu Analisis Statistik Deskriptif, analisis Regresi Logistik.

Hasil penelitian menunjukkan bahwa ukuran perusahaan, leverage, dan kualitas audit tidak berpengaruh terhadap penghindaran pajak. Sedangkan profitabilitas berpengaruh positif terhadap penghindaran pajak.
Pengaruh Fee Audit, Ukuran Perusahaan, Audit Tenure Terhadap Kualitas Audit (Studi Empiris Pada Perusahaan Manufaktur Yang Terdapat Di Bursa Efek Indonesia Periode Tahun 2014-2018)
Authors: Galih Chandra Kirana  , M. Arif Assafiq
Published: January 2022

Penelitian ini menguji pengaruh biaya audit, ukuran perusahaan, dan masa kerja audit terhadap Quallitas audit. Populasi dalam penelitian ini adalah perusahaan manufaktur yang terdaftar di BEI tahun 2014-2018 yang diakses melalui website resmi BEI yaitu www.idx.co.id. Metode pengambilan sampel yang digunakan dalam penelitian ini adalah purposive sampling, dimana sampel diambil dari populasi sebanyak 166 dan selanjutnya menghasilkan sampel sebanyak 310 pengamatan. Sedangkan metode analisis yang digunakan dalam pengujian hipotesis ini adalah analisis regresi logistik, dengan menggunakan aplikasi SPSS versi 2.6.

Hasil penelitian secara parsial membuktikan bahwa audit fee dan audit tenur berpengaruh signifikan terhadap kualitas audit, sedangkan untuk ukuran perusahaan sendiri tidak berpengaruh signifikan terhadap kualitas audit. Hubungan yang signifikan ini bernilai positif yang artinya jika variabel bebas meningkat maka variabel terikat juga meningkat begitu juga sebaliknya.