bluuebunny/crossref_metadata_2025 huggingface dataset:
pplications of Artificial Intelligence in Dentistry: A Narrative Review
Authors: Sikri Arpit , Sikri Jyotsana , Piplani Vritti , Thakur Yamika
Published: January 2024

Artificial intelligence, rooted in the information technology sector, stands as a transformative force driven by sophisticated software mechanisms that confer numerous benefits across a wide array of societal domains. Among these, its integration into the healthcare sector, including dentistry, has proven to be a source of considerable success. The impact is particularly noteworthy in the realm of preventive healthcare, where AI demonstrates substantial potential for advancing early diagnosis, ultimately resulting in elevated treatment efficacy. The exploration of diverse use cases reveals a promising landscape where AI not only facilitates precision in diagnostics but also plays a pivotal role in optimizing treatment outcomes. Through its analytical capabilities and pattern recognition, AI contributes to a more nuanced and accurate early detection of dental issues, thereby empowering dental professionals to intervene at the earliest stages. The implications extend beyond diagnostic accuracy, encompassing tangible improvements in the overall patient experience. By leveraging AI, treatment durations can be streamlined, leading to more efficient and effective interventions. This not only translates to enhanced patient comfort but also contributes to the professional satisfaction of dental practitioners who can deliver high-quality care with greater precision. Furthermore, the synthesis of AI into dental practices introduces a dynamic paradigm shift, fostering a synergy between technology and human expertise. As algorithms evolve and learn from vast datasets, they augment the diagnostic acumen of dental professionals, providing valuable insights that may have been challenging to discern through traditional means alone. This narrative review explores the diverse applications of artificial intelligence in dentistry, emphasizing its transformative potential. From early diagnosis to treatment optimization, the integration of AI not only enhances clinical outcomes but also fosters a more patient-centric and efficient approach to dental care. The evolving collaboration between AI and dental practitioners is set to redefine oral healthcare, paving the way for a future where precision and efficiency converge to elevate the standards of dental medicine.
Nanotechnology in Prosthodontics: A Review
Authors: Al-Jammali Zainab Mahmood , Al-Yasiry Anas , Alyassery Aoss Moez Abed –Alhussian
Published: January 2024

Background: Numerous biomaterials used in prosthodontics have demonstrated dramatically improved performances after having their scales decreased by nanotechnology from micron to nano size. Contrarily, numerous nanocomposites made of nanomaterials and conventional metals, ceramics, resins, or other matrix materials have been extensively used in prosthodontics because the addition of the nanomaterials significantly improved the materials' properties, including modulus elasticity, surface hardness, polymerization shrinkage, and filler loading. Aim of the Study: In this paper, the most recent advancements in research on the prosthodontic applications of nanometals, nanoceramics, nano resins, and other nanomaterials were reviewed. This review not only provides a detailed description of the most recent related investigations, but also, hopefully, serves as an important elicitation for future studies in this area. Conclusion: Nanomaterials have proven fundamental to the development of basic science and clinical technology in prosthodontics. It demonstrates how the prosthodontic materials' many properties, including modulus of elasticity, surface hardness, polymerization shrinkage, and filler loading, can be significantly improved after their scales were reduced from micron to nano size by nanotechnology.
Various of Chemical and Pharmacological Applications of 1,3,4-Thiadiazole and It’s Derivative
Authors: Shia Jaafar Sataar , Ibrahim Marwan S. , Al-Darraji Asmaa Safwan
Published: January 2024

1,3,4-Thiadiazole is a heterocyclic compound that has been widely studied for its diverse pharmacological activities. The compound is synthesized using different methods, including cyclization of linear organic derivative. The compound has been shown to exhibit various bioactivity, including its property as anticancer toward human cancers, antibacterial, diuretic, antitubercular, antifungal, and leishmanicidal agents, additionally, 1,3,4-thiadiazole derivatives have been shown to influence the central nervous system, displaying anti-inflammatory, anticonvulsant, analgesic, anxiolytic and antidepressant effects. 1,3,4-thiadiazole and its derivatives have been a subject of extensive research in the field of medicinal chemistry. These compounds exhibit a wide range of pharmacological activities, making them valuable candidates for drug development. The structural versatility of 1,3,4-thiadiazole derivatives allows for the fine-tuning of their pharmacological effects. The 1,3,4-thiadiazole moiety in a molecule enhances its bioactivity. Medicinal chemists have explored the SAR (Structure-Activity Relationship) of these derivatives to understand how different substitutions and modifications impact their pharmacological profiles. Synthesis and pharmacological activities of 1,3,4-thiadiazole and also its derivatives represent a vibrant area of research with promising implications for the progress of new therapeutic agents across various medical domains.
Evaluation of Phytochemical Screening, Antioxidant, and Thrombolytic Activity of Methanolic Extract of Phlogacanthus thyrsiflorus
Authors: Tamanna Afrin Jahan , Saha Avijit , Hoque Majedul , Md. Aktaruzzaman Md. Aktaruzzaman , Hasan Md. Nahid
Published: January 2024

Objective: The main objectives of the study are preliminary phytochemical screening, antioxidant activity and in vitro thrombolytic activity evaluation of extract Phlogacanthus thyrsiflorus. Methods: Preliminary phytochemical analysis was done by using standard methods. Human blood clot lysis was used to evaluate the thrombolytic activities. The antioxidant activity is evaluated by free radical scavenging activity of DPPH (1,1-diphenyl-2-picrylhydrazyl) method and total phenolic content. Results: Preliminary phytochemical screening revealed the presence of various bioactive components like Tannin, Saponins, Phenol and Flavonoids. In thrombolytic assay, a significant clot lysis was observed plant extract compared to the negative control. The plant could be beneficial in synthetic drug formulation by virtue of the presence of antioxidant activity. The crude extract of plant were found to have Antioxidant activity with the concentration of 20 µg/ml, 40 µg/ml, 60 µg/ml, 80 µg/ml, 100 µg/ml respectively compared to control and standard. In DPPH scavenging assay, IC50 values of extract and ascorbic acid were found to be 31.87 µg/ml and 52.04 µg/ml respectively. Total phenol content was 10.5 mg. Conclusion: In conclusion, with this study it could be concluded that the phytochemical, antioxidant assay and thrombolytic activity of methanol extract Phlogacanthus thyrsiflorus would give valuable information for further characterization and exploitation of this important medicinal plant.
In Vitro Study of the Antiparasitic Activity of Vitellaria paradoxa Gaertn (Sapotaceae) on the Parasite Onchocerca ochengi
Authors: Djetoloum Martinien Atakewang , Bessimbaye Nadlaou , Mbailao Mbaïnguinam
Published: January 2024

Onchocerciasis is a parasitic disease that affects millions of animals and people around the world. A recipe based on Vitellaria paradoxa is used in traditional medicine against this disease in Chad. The objective of this study was to evaluate the antiparasitic activities of extracts from the roots, fruits, leaves and bark of Vitellaria paradoxa on the parasitic nematode Onchocerca ochengi, a model similar to Onchocerca volvulus used in the research of control drugs. against onchocerciasis. The identification of parasites and the hydroethanolic extracts of the different planar organs were carried out at the Laboratory of Research, Diagnostics and Scientific Expertise (LaboReDES) of the Faculty of Human Sciences, University of N'Djamena using the methods of Ndjonka et al., 2012. The extracts of this plant were tested at different concentrations (0.1; 0.2; 0.3; 0.4 mg/mL) in the RPMI-1640 culture medium. The antiparasitic activity was noted according to the mortality rate after 72 hours of incubation of Onchocerca ochengi at 37°C. The LC50 values were then graphically determined at the end of this incubation. They were 0.05 mg/mL for the roots; 0.06 mg/mL for fruits; 0.05 mg/mL for the leaves and 0.06 mg/mL for the bark. These results confirm the effectiveness of Vitellaria paradoxa used in traditional medicine to treat parasitosis. This plant also has the same effects as ivermectin. The V. paradoxa root test on microfilariae shows an LC50 value of 0.05 mg/mL in 24 hours of incubation. This study showed that the hydroethanolic extracts of the bark of Vitellaria paradoxa had antiparasitic activities, allowing the development of a new molecule active against these parasitic infections and also the extracts of this plant could be used as alternatives to treat infections in case of parasite resistance to ivermectin.
Leveraging Artificial Intelligence and Machine Learning in Predicting and Managing Pandemics: Lessons Learnt and Future Implications in the Healthcare Sector
Authors: Mudenda Steward , Mohamed Shafiq
Published: January 2024

Artificial intelligence (AI) is a game changer in the healthcare, educational, and other sectors. The use of AI in the healthcare sector has shown that AI and machine learning should be promoted in the improvement of service provision, including in predicting and managing pandemics. This study assessed the roles of AI in predicting and managing pandemics with lessons learnt from the COVID-19 pandemic. A narrative review was conducted from December 2023 to January 2024 on the role of AI and machine learning in predicting and managing pandemics. A literature search was done using PubMed and Google Scholar. This study found that AI is useful in the healthcare sector and can be used to predict and manage pandemics. Additionally, AI can be used in disease modelling and improve public health service provision. There is a need to promote and strengthen the use of AI and machine learning in the healthcare sector.
Comparative Study to Assess the Safety and Effectiveness of Methotrexate and Tofacitinib in Patients Diagnosed with Rheumatoid Arthritis
Authors: Johnson Carol Ann , Kuriakose Ms. Sheethal
Published: January 2024

Introduction: Rheumatoid Arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints resulting in pain and disability. The prevalence of RA is estimated to be 1% to 2% globally and does not have any ethnic or racial differences. Elevated C-Reactive Protein (CRP) levels in the blood indicate the presence of inflammation and can be used to detect and monitor the disease. Patients with RA tend to have a significant load in association with pain, disability and activity limitation which in turn affects the Health-Related Quality of Life. With a growing rate of RA globally there is a need to assess the safety and effectiveness of drugs and provide a suitable treatment to improve the quality of life of the patients. OBJECTIVES: The goal of the study was to compare the safety and effectiveness of Tofacitinib and Methotrexate in patients diagnosed with Rheumatoid Arthritis. The study also aimed to assess the Health-Related Quality of Life (HRQOL) of patients. Methodology: This was an observational study conducted in selected Orthopaedic clinics in T. Dasarahalli Bengaluru. All the subjects (n=40) meeting the inclusion and exclusion criteria were briefed about the purpose of the study and the informed consent was obtained. The subject’s demographic details and responses were collected. Standard questionnaires, 36-Item Short Form survey (SF-36) to assess the HRQOL and Health Assessment Questionnaire-Disease Index (HAQ-DI) to assess the effectiveness of the drugs were used in all patients. The collected data were entered in Microsoft Excel and appropriate descriptive and statistical analysis was performed. Results: A total of 40 samples were enrolled in the study based on Inclusion and Exclusion criteria. Out of which 50% of the participants were on Methotrexate (MTX) and the other 50% were on Tofacitinib. Majority of the subjects in the study were women (90%) and men (10%) with mean age 51 and 54 respectively. On comparing the effectiveness of both
Correlation of Early Cognitive Impairment in Intracerebral Haemorrhage from Tertiary Care Hospital of North Karnataka
Authors: M Dhananjaya , Hukkeri Kiran , Sharankumar Sharankumar , Manoj Manoj
Published: January 2024

Objectives: To identify the correlation of early cognitive impairment following intracerebral haemorrhage. Methods: A total of 30 adult patients (>15 years) with intracerebral hemorrhage were enrolled in the study. Demographic profile, clinical and radiological profile of the patients was noted. Cognitive status at discharge was assessed using Montreal Cognitive Assessment (MoCA). Results: Mean age was 63.53±12.11 years. Majority were males (56.7%). All the patients had cognitive impairment - majority (76.7%) had moderate cognitive impairment followed by severe impairment (16.7%) and mild impairment (6.7%) respectively at time of discharge. History of tobacco use showed a significant association with severe cognitive impairment. Conclusions: Mild to moderate cognitive impairment is quite frequent among intracerebral hemorrhage patients at time of discharge irrespective of the clinical, demographic and radiological profile.
Endoscopic Extraction of an Unusual Foreign Body at the Somine Dolo Hospital in Mopti
Authors: A Kondé , L Sidibé , D Katilé , A Diarra , N Dembélé , Y Fofana , I Koné , M Bah , D Samake , A Maïga , O Mallé , M Dicko , M Diarra , A Konaté , MY Maïga
Published: January 2024

The esophagus is the most common site of impaction of an ingested foreign body. The main initial symptom is acute dysphagia; Patients with complete esophageal obstruction produce excessive amounts of saliva and are unable to swallow oral secretions. Complete obstruction can cause pressure necrosis and increases the risk of perforation if present for more than approximately 24 hours. Emergency endoscopy is necessary for sharp objects, disc or button batteries, and any obstruction causing symptoms that suggest complete obstruction. We report through this observation the extraction of an unusual esophageal foreign body at the Sominé Dolo hospital in Mopti. This was a 60-year-old patient, a farmer, with no known medical or surgical history to date, and no particular psychiatric disorder. The accidentally ingested foreign body was a cap from a recycled vinegar bottle. An attempt at extraction in the ENT department was made without success, then subsequently sent to the Hepato-gastroenterology unit. The endoscopic extraction of the foreign body was carried out without incident and the evolution was favorable after the endoscopy procedure.
Exploration and Utilization of Curriculum Ideological and Political Education in Human Geography Teaching
Authors: Xueling Wu , Yan Cao
Published: January 2024

Curriculum ideological and political education is an effective way to cultivate talents for socialist construction in the new era. Human geography urgently needs the integration of curriculum ideology and politics. Under the background of new requirements in the new era, the ideological and political construction of curriculum is explored. By excavating the ideological and political elements of human geography curriculum, starting from the concept of national conditions, life values, sustainable development concept, and human-land coordination concept, this paper explores the corresponding integration points of ideological and political elements in each chapter, and integrates the ideological and political contents such as world outlook, political outlook, moral outlook, outlook on life, and rule of law into the human geography classroom, so as to cultivate students' cognitive ability and practical ability, improve their social responsibility and ability to identify right and wrong, and realize the educational effect of “moistening things silently”.
An Analysis of Prodigal Plays in the English Renaissance
Authors: Zhao Yonggang
Published: January 2024

The fable of the prodigal son was widely dramatized during the English Renaissance, and the prodigal pattern permeated the entire theater of the that time. This article provides an overview of the prodigal plays, exploring the reasons for the popularity of prodigal plays during the Renaissance and the characteristics of its development at different stages during that period.
Narrative Reading Therapy: Application Practice and Exploration of Psychological Intervention for College Students in the New Era
Authors: Yin Siying , Tu Yulong
Published: January 2024

In the new era, college students are in a critical period of shaping their personality and values and are vulnerable to the influence of the Internet and family environments. At the same time, the social-psychological assistance service is not yet perfect, which leads to their failure to receive timely adjustment when they have psychological abnormalities. To solve this problem, this article conducts a comparative study by integrating traditional psychological Therapy and currently popular psychological Therapy and proposes that the use of narrative therapy theory and reading therapy theory can effectively intervene in the psychological abnormalities of college students in the new era, and discusses the practice and application prospects of this method.
Relationship Between Smoking Behavior, Alcohol Consumption, Sexual and Reproductive Health with Adolescent Health Quality of Life in East Bolaang Mongondow Regency
Authors: Lijoed Marlina Dhamayanti , Manampiring Aaltje , Kes M. , Posangi Jimmy , Ratag Gustaaf , Rombot Dina
Published: January 2024

The adolescent period is often considered a healthy phase of life. Risky behaviors such as smoking, alcohol consumption, and casual sex pose significant challenges to their quality of life. Data and research indicate that these behaviors not only impact physical health but also worsen the overall quality of life. The objective of this research is to analyze the relationship between smoking behavior, alcohol consumption, sexual and reproductive health, and the health-related quality of life among adolescents in East Bolaang Mongondow Regency. This study is quantitative, utilizing an analytical observational method with a cross-sectional approach. The sample size consists of 428 respondents. Primary data was obtained through interviews using questionnaires, while secondary data includes information obtained from schools in East Bolaang Mongondow Regency, such as student data, geographical and demographic descriptions. Data analysis in this study includes descriptive, bivariate (Chi-square), and multivariate (logistic regression) analyses. The research findings reveal that there is a relationship between smoking behavior and the health-related quality of life among adolescents in East Bolaang Mongondow Regency in all domains (physical domain p=0.000, psychological p=0.001, social p=0.000, and environmental p=0.000). There is also a relationship between alcohol consumption and the health-related quality of life among adolescents in East Bolaang Mongondow Regency in all domains (physical domain p=0.000, psychological p=0.017, social p=0.060, and environmental p=0.047). However, there is no relationship between sexual and reproductive health and the health-related quality of life among adolescents in East Bolaang Mongondow Regency in all domains (physical p=0.733, psychological p=0.465, social p=0.098, and environmental p=0.966). In conclusion, smoking and alcohol consumption, except in the social domain, are related to the health-related quality of life among ......
Analyzing the Relationship Between Smoking Habit, Age, Gender, and Alcohol Consumption Regarding to the Health-Related Quality of Life in Junior and High School Students in the East of Bolaang Mongondow Regency
Authors: Kabaikan Alfianus Stevy , Ratag Gustaf A.E. , Kepel Billy J. , Manampiring Aaltje , Umboh Jootje
Published: January 2024

Adolescence is often characterized by high-risk factors that threaten their health. Risky behaviors such as smoking, alcohol consumption, and unprotected sexual relationships pose significant challenges to their quality of life, including adolescents in East Bolaang Mongondow Regency. Data and research indicate that these behaviors not only affect physical health but also deteriorate overall quality of life, emphasizing the importance of a deeper understanding and effective policy planning to enhance the health conditions and overall well-being of adolescents. The research aims to analyze the relationship between smoking habits, age, gender, and alcohol consumption concerning the health-related quality of life of junior high school and high school students in East Bolaang Mongondow Regency. The research type is quantitative, employing an observational analytical method with a cross-sectional approach. The sample comprises 435 respondents. Primary data is collected through interviews using questionnaires, while secondary data is obtained from schools in the East Bolaang Mongondow Regency. Data analysis for the research includes descriptive analysis, bivariate analysis (Chi-square), and multivariate analysis (logistic regression). The research findings indicate that there is a relationship between smoking behavior and the health-related quality of life of adolescents in East Bolaang Mongondow Regency in all domains (physical domain p=0.015, psychological domain p=0.004, social domain p=0.002, and environmental domain p=0.000). There is a relationship between alcohol consumption and the health-related quality of life of adolescents in East Bolaang Mongondow Regency in all domains (physical domain p=0.000, psychological domain p=0.000, social domain p=0.000, and environmental domain p=0.000). There is a relationship between age and the health-related quality of life of adolescents in East Bolaang Mongondow Regency in the domains (physical domain p=0.000, ........
Analysis of the Correlation between Physical Activity, Nutritional Status, and Learning Achievement with the Health Quality of Adolescents Life in East Bolaang Mongondow Regency
Authors: Sugeha Bonita , Ratag Gustaaf , Manampiring Aaltje , Posangi Jimmy , Fatimawali Fatimawali
Published: January 2024

Quality of life is one of the criteria currently used to evaluate healthcare interventions. The aim of this study is to assess the relationship between physical activity, nutritional status, and academic performance with the health-related quality of life of adolescents in East Bolaang Mongondow Regency. This research is a correlational study with a cross-sectional approach conducted in junior high schools and high schools in East Bolaang Mongondow Regency in October 2023, with a total sample size of 430. The instrument used in this study is a questionnaire, and the data were analyzed using univariate and bivariate analysis with the Chi-Square test. The results of the study showed that the variable of physical activity had a p-value < 0.05 in the domains of physical health (p=0.000), psychological health (p=0.000), and environment (p=0.000). However, for the social relationships domain, the p-value was > 0.05 (p=0.100). The variable of nutritional status had a p-value < 0.05 in the domains of physical health (p=0.000), psychological health (p=0.002), social relationships (p=0.000), and environment (p=0.000). The academic performance variable had a p-value > 0.05 for all domains. The conclusion of this study is that physical activity is associated with the quality of life in the domains of physical health, psychological health, and environment. Nutritional status is associated with all domains of quality of life, while academic performance is not associated with the quality of life in any domain.
Functional Outcome of Tibialis Posterior Tendon Transfer to Tibialis Anterior & Peroneus Longus among Foot Drop Patients- a Prospective Study
Authors: Monir Mohammad Moniruzzaman , Das Krishna Priya , Hoque Shah Md. Samsul , Ahmed Md. Bulbul
Published: January 2024

Introduction: Foot drop is described as the loss of active ankle dorsiflexion due to neurologic, systemic, or traumatic causes. The purpose of this study was to assess the functional outcome of tibialis posterior tendon transfer to tibialis anterior and peroneus longus in patients with foot drop. Aim of the study: The aim of this study was to evaluate the functional outcome of tibialis posterior tendon transfer to tibialis anterior and peroneus longus in patients with foot drop. Methods: This study was a randomized clinical trial that evaluate the results of tibialis posterior tendon transfer surgeries for patients with foot drop. The patients met certain inclusion and exclusion criteria, and gave written consent before the surgeries. The patients were followed up for six months after the surgery, and evaluated using the Stanmore assessment questionnaire and other measures. Result: The study enrolled 30 patients (26 males and 4 females) with mean age being 35.40 years. We evaluate tibialis posterior tendon transfer to tibialis anterior and peroneus longus for foot drop in the patients. After 24 weeks, all patient improved in foot dorsiflexion, eversion, function, posture, and satisfaction. 26 (86.70%) patients did not need orthosis and 28 (93.30%) had balanced foot posture with no deformity. Conclusion: The results showed all patient had significant improvement after the surgery. Therefore, this study concluded that tibialis posterior tendon transfer can be used effectively and safely for the management of foot drop.
Incidence and Outcome of Iatrogenic Gallbladder Perforation during Laparoscopic Cholecystectomy in a Tertiary Care Hospital
Authors: Ahmed Sheikh Sabbir , Jahan Mst Wazira Shefat , Hossain Shakhawat
Published: January 2024

Introduction: in developing countries, patients getting admitted into hospital is influenced by gallbladder stone. In this study, the incidence and outcome of iatrogenic gallbladder perforation during laparoscopic cholecystectomy was observed and studied for further development in this sector in a tertiary care hospital. Aim of the study: The aim of this study was to find out the incidence and outcome of iatrogenic gallbladder perforation during laparoscopic cholecystectomy. Methods: This prospective observational study was conducted in Department of Surgery, Combined Military Hospital (CMH) Dhaka, Bangladesh during the period from June 2018 to November 2018. This study had institutional review board approval and informed consent for 100 patients age range 31-70 years (mean 50.3±10.6) in gallbladder perforation group and in no perforation group the range was 25 to 62 years (mean 47.9±12.3). The patients went through laparoscopic cholecystectomy through four port and gallbladder was removed through hepigastric port. The ultrasonographic report of all patients were collected. Result: In the present study, majority 86 patients were found normal body weight (BMI 18.5-24.9 kg/m2) but female patients were high in number of affected list, 14(73.7%) in gallbladder perforation group and 56(69.1%) in no perforation group. A single stone is mainly found in no perforation group which is 32(39.5%). Multiple stone is found less in both of the groups respectively. Staying in the hospital was also higher in gallbladder group in comparison with no perforation group. Conclusion: According to the study, perforation in gallbladder due to laparoscopic cholecystectomy is not deniable (19%). This can result in peroperative pain and more stay in hospital.
Asymptomatic Malaria during Blood Transfusion in N’Djamena, Chad: Associated Risk Factors among Blood Donors
Authors: Djimadoum Mbanga , Nadlaou Bessimbaye , Magloire Maoundié
Published: January 2024

Background: Malaria is a parasitic disease transmitted to humans through the bite of a female mosquito (Anopheles). however, blood transfusion, which is a life-saving medical procedure in many settings, represents a potential route of Plasmodium transmission. The objective of this study was to determine the plasmodial parasitemia in blood donors with a view to assessing the quality of the erythrocyte concentrates produced at the National Blood Transfusion Center (CNTS) of Chad. Methods: This was a cross-sectional analytical study involving 271 subjects who came to donate blood at the CNTS in N'Djamena over a period from March 1 to June 1, 2023. After obtaining the tacit and/or informed consent of potential donors, a questionnaire was administered to them to collect sociodemographic data, knowledge and practical attitudes towards malaria. A blood sample was taken from each individual. The following biological analyzes were carried out: Malaria Rapid Diagnostic Test, thick smear, blood smear. Data were entered and analyzed using SPSS software version 26.0, and the Chi square test was used to compare proportions and a logistic regression model to look for risk factors associated with malaria infection. Results: This study reveals that: the most represented age group was that of 18-28 years (68.6%), with a sex ratio of 4.1 in favor of the male sex, family type donors were more represented (73.4%). The prevalence of plasmodial infection was 12.2% with a parasitemia of between 100 and 600 parasites/µL of blood. The species in question was Plasmodium falciparum. A statistically significant association was established between sex, non-use of insecticide-treated mosquito nets, lack of knowledge about malaria and malaria infection. Conclusion: This work showed that the residual transfusion risk of malaria is real at the CNTS. It would therefore be necessary to ultimately adopt an innovative safety strategy including systematic screening of donations for Plasmodium falciparum.
Thyroid Localization of Breast Cancer: About a Case and Literature Review
Authors: Benyahia Radia , Abada Fathi , Imene Imene , Bendib Salah Eddine
Published: January 2024

Introduction: Thyroid localization of breast cancer is rare and has a poor prognosis. Common metastatic sites of mammary carcinoma are pulmonary, hepatic and bone. Clinical diagnosis of thyroid metastasis from malignancy is difficult. We report a case of thyroid metastasis of mammary origin. We then discuss the diagnostic methods and their peculiarities in the identification of such lesions. Observation: This was a 47-year-old patient who underwent a left mastectomy with ipsilateral axillary lymph node dissection in 2014 and was presented 9 years later following the onset of a thyroid mass and right spinal lymphadenopathy. Cervical imaging revealed cervical lymphadenopathy of spinal site and nodular goiter classified as EU-TIRADS 4. A cytopuncture of the cervical lymphadenopathy and thyroid nodule is performed. Cytology revealed thyroid metastasis from mammary carcinoma and metastatic cervical lymphadenopathy. The patient underwent surgery (total thyroidectomy) confirming the diagnosis. Conclusion: The diagnosis of thyroid metastasis should be suspected in patients with a history of neoplasia prior to nodular goiter. The treatment for these metastases is that of primary cancer.
Hubungan Ankle Brachial Index Dengan Lama Penyembuhan Osteomielitis Ekstremitas Bawah di RSUD Waled
Authors: Athira Fathin Syadzwana , Indrakusuma Mohammad Erwin , Putro Widiyatmiko Arifin
Published: January 2024

Osteomielitis adalah suatu peradangan pada tulang yang disebabkan oleh infeksi. Insiden osteomielitis di Indonesia adalah sekitar 0,5-2,4 kasus per 100.000 orang. Salah satu pemeriksaan yang digunakan sebagai indikator kapasitas fungsional pembuluh darah pada tungkai bawah dapat dilakukan dengan pemeriksaan Ankle Brachial Index. American Heart Association (AHA) mendefinisikan ABI sebagai perbandingan tekanan darah sistolik yang diukur pada arteri di pergelangan kaki dan arteri brachial. Tujuan penelitian ini untuk menganalisis hubungan Ankle Brachial Index dengan lama penyembuhan osteomyelitis ekstremitas bawah di RSUD Waled. Metode penelitian ini metode observasional menggunakan desain cross sectional. Data responden pasien osteomielitis diambil sebanyak 19 sampel di RSUD Waled pada bulan Juli tahun 2023. Penelitian ini dianalisis dengan uji univariat dan bivariat menggunakan uji Spearman untuk menganalisis hubungan Ankle Brachial Index dengan lama penyembuhan osteomielitis ekstremitas bawah di RSUD Waled. Data responden pasien osteomielitis dengan ABI <0,90 sebanyak 6 orang (31,6%) dan responden dengan nilai ABI 0,90-1,40 sebanyak 13 orang (68,4%). Analisis hubungan dengan uji spearman diperoleh nilai koefisien korelasi sebesar -0,527 dengan nilai p value sebesar 0,010 (p< 0,05) yang memiliki makna terdapat hubungan antara Ankle Brachial Index dengan lama penyembuhan osteomielitis ekstremitas bawah. Kesimpulan penelitian ini terdapat hubungan antara Ankle Brachial Index dengan lama penyembuhan osteomielitis ekstremitas bawah di RSUD Waled.
FISHERIES ECONOMICS-A LITERATURE REVIEW
Authors: Reshma  , Dr. Shripathi Kalluraya
Published: January 2024

Fisheries economics refers to the study of economic activities related to the management, production, and distribution of fishery resources. It involves analysing the economic aspects of fishing, aquaculture, and the overall seafood industry. This field explores topics such as resource allocation, market dynamics, policy implications, and sustainability within the context of fisheries and aquatic ecosystems. Fisheries economics refers to the branch of economics that focuses on the economic aspects of the fishing industry. It involves the study of the production, distribution, and consumption of fish and seafood, considering factors such as market dynamics, resource management, trade, and policy implications. The goal is to understand and analyse the economic behaviour and decision-making within the fisheries sector to promote sustainable practices and efficient resource utilization. Fisheries economics is a field of study that focuses on the economic aspects of fisheries and aquaculture. It involves analysing the allocation of resources, production, distribution, and consumption of fishery-related goods and services. This discipline examines the economic behaviour of individuals, businesses, and governments within the context of fisheries management, sustainability, and the impact of policies on the fishing industry.
CLASSIFICATION OF TYPES OF ONLINE STORES AND ANALYSIS OF THE FEATURES OF THEIR DEVELOPMENT TECHNOLOGIES
Authors:   Yaroslavl State Technical University, Voevodina Elena I. , Burykin Alexey D. ,   Yaroslavl State Technical University; Academy of Labor and Social Relations
Published: January 2024

The article is a comprehensive analysis of the relevance and applicability of online stores as a key sales channel for companies. The article presents a classification of various types of online stores, highlighting the features of each type and emphasizing their compliance with the needs of various business models. The technical aspects of creating online stores are covered, including issues of choosing platforms and programming languages. The article includes a comparative analysis of various technological solutions, providing information about the advantages and disadvantages of choosing specific platforms and programming languages for creating online stores. This approach allows businesses to make informed decisions when developing and implementing their online trading platforms, as well as effectively using them to optimize business processes and maximize profits in the modern digital market.
Comparative characteristics of quantitative methods for the determination of flavophospholipol in medicinal preparations by the agar diffusion method
Authors:   All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russia, Muravyeva Victoria B. , Soboleva Natalya I. ,   All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russia, Zavyalov Artem V. ,   All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russia, Makhlis Oleg A. ,   All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russia, Likhikh Tatyana N. ,   All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russia, Kis Irina V. ,   All-Russian State Center for Quality and Standardization of Medicines for Animals and Feed, Moscow, Russia
Published: January 2024

Flavophospholipol is a phosphoglycolipid antibiotic that inhibits the development of gram-positive microorganisms in the gastrointestinal tract, slows down the growth of gram-negative bacteria Salmonella spp. and E.coli, without having a negative effect on lactobacilli and bifidobacteria, helps to reduce the extrachromosomal resistance of microorganisms to antibacterial agents, increasing their effectiveness. Preparations based on flavophospholipol are used for piglets and pigs, cattle and calves, rabbits and fur-bearing animals, poultry for prophylactic purposes in case of bacterial diseases, the pathogens of which are sensitive to flavofoslipol. In recent years, drugs based on flavophospholipol have been used in veterinary practice. In this regard, it is relevant to develop a methodology for the quantitative determination of flavophospholipol in medicinal preparations for veterinary use using the microbiological method (agar diffusion method). The authors established test strains capable of exhibiting growth inhibition under the action of flavophospholipol and its seed dose. By selecting various combinations, a nutrient substrate and its component composition were selected, depending on the needs of the microorganism, the incubation conditions and the concentration of the standard of the tested antibiotic were determined. The optimal experimental conditions for determining the quantitative determination of flavophospholipol in antimicrobial preparations by the agar diffusion method were established.
Determination of chronic toxicity of a complex preparation for rabbits based on protein hydrolyzate
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Deltsov Alexander A. , Bachinskaya Valentina M. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Rodkina Olga R. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: January 2024

This paper presents the results of a study of the chronic toxicity parameters of a new complex drug containing organic iodine, as well as a number of other microelements and vitamins, with repeated intragastric administration to laboratory rats at a dose of 28 and 20 ml per head for 50 days. The studied complex iodine-containing drug, when administered repeatedly orally to laboratory animals, does not have a negative effect on blood and urine parameters, does not affect the results of scatological examination, and does not cause the death of animals. Therefore, the study drug does not have chronic toxicity.
Complex diagnosis of acute pancreatitis in dogs
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Kruglova Yulia S. , Muradyan Zhora Yu. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Nazimkina Svetlana F. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: January 2024

This article presents typical results obtained from a general clinical blood test in dogs with signs of pancreatic pathology: leukocytosis with a shift to the left, thrombocytopenia, anemia, increased ESR. In the diagnosis of acute pancreatitis, an increase in a-amylase and lipase in the blood serum is considered important indicators. It is believed that the a-amylase activity indicator immediately indicates lesions of the pancreas, however, studies have been conducted that indicated that when the a-amylase level was normal, but the lipase level was elevated, the diagnosis of pancreatitis was confirmed. Therefore, an increase in the lipase enzyme is more specific for the diagnosis of pancreatitis. It is important to determine both enzymes to diagnose pancreatic lesions. The best diagnostic indicator of acute pancreatitis is an increase in lipase, a-amylase and creatinine, which gives up to 98 % accuracy in making a diagnosis. With pathologies of the pancreas, patients often experience disturbances in carbohydrate metabolism. As a rule, this is manifested by signs of diabetes mellitus, i.e. increase in serum glucose. The disorders are explained by damage to the cells of the islet apparatus of the pancreas. Research has shown that the canine pancreatic lipase test (SNAP®cPL) is better than other methods for diagnosing acute pancreatitis in dogs. To better test for pancreatitis in animal examinations, the SNAP®cPL Test also measures cPL concentrations using ELISA technology. Thus, the test for pancreatic lipase gave a 100 % result, which confirms its high sensitivity.
Morphological characteristics of pectoral muscles of broiler chickens of the «Smena-9» cross with different feeding diets
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Stepanishin Viktor V. , Borkhunova Elena N. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Kondratov Gleb V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Kuznetsova Maria A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Zharikov Aleksey M. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: January 2024

The article presents the results of studies of the structural features of the superficial pectoral muscle in broiler chickens of the Smena-9 cross with various feeding diets on the 35th day of ontogenesis, carried out within the framework of the thematic plan-tasks for the implementation of research works by state order of the Ministry of Agriculture of Russia on the topic: «Development of theoretical foundations and methodology for the practical use of morphological criteria in assessing the quality and safety of poultry products». It is shown that the studied muscle has a typical bundle structure and is differentiated into a muscular and connective tissue component (endomysium and perimysium). Along with this, signs of increased growth processes were revealed against the background of the use of feed additives, which is manifested by an increase in the thickness of muscle fibers and their bundles and an increase in the number of hemocapillaries compared with the control group. A looser packing of muscle bundles with a better development of perimysium and the formation of white adipose tissue in it in representatives of the experimental groups may indicate a potential improvement in the taste qualities of meat compared to the control. The obtained data can be used as morphological criteria for a comprehensive assessment of poultry meat products during commodity and veterinary-sanitary expertise, and are also important for further developments to improve domestic chicken meat crosses
Assessment of the first food of hydrobionts in the ecosystems of small rivers of Kabardino-Balkaria (on the example of the Nalchik river)
Authors:   Kabardino-Balkarian State Agrarian University named after V. M. Kokov, Nalchik, Russia, Pezheva Madina Kh. , Umarov Kazbek K. ,   Kabardino-Balkarian State Agrarian University named after V. M. Kokov, Nalchik, Russia, Yakimov Andrey V. ,   Nalchik State Experimental Hunting Farm, Nalchik, Russia, Redkin Sergey V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: January 2024

The article provides information about the drift of the natural food base of fish. The species composition of hydrobionts is given, the role of drift as the first food for river fish species is shown, their role in the diagnosis of the current ecological state of the small Nalchik river is determined.
"Exploring the Impact of Online Learning on Student Academic Performance in Higher Education"
Authors: Anam Nazneen Tara  , Asma Tariq  , Yan Zhang
Published: January 2024

This research investigates the impact of online learning on student engagement and academic performance in the higher education landscape. In a sample of 300 students from public sector universities in Punjab, Pakistan, the researcher examined online learning experiences, demographic factors, and academic performance. The descriptive statistics revealed moderately positive online learning experiences and moderately favorable academic performance on average, accompanied by significant variability within the sample. Correlation analysis, however, unveiled very weak and often statistically insignificant relationships between these variables, suggesting complex and non-linear dynamics at play. Consequently, we advocate for personalized support, adaptable pedagogical approaches, inclusivity, accessibility, and interdisciplinary collaboration as essential components to enhance online learning. Moreover, this study calls for continued research to unearth the intricate dynamics of online education's influence on student outcomes, driving the evolution of evidence-based practices in higher education. The study underlines the necessity for continued research into online education's complex dynamics and student outcomes. This includes studying new technology, learning analytics, and pedagogical methods to inform evidence-based practices in higher education.
Analysis of Airline Passenger Satisfaction Using Decision Tree and Naïve Bayes Algorithms
Authors: Suprapto Devita Sertivia , Oetama Raymond
Published: January 2024

In the dynamic landscape of airline services, comprehending the intricacies that mold customer satisfaction is paramount to elevating overall service quality. This study aspires to dissect these pivotal elements, contributing nuanced insights that can propel the enhancement of customer satisfaction within the industry. A multifaceted investigation encompasses analyzing demographic data, exploring underlying factors significantly shaping passenger satisfaction, and identifying the most adept model for forecasting imminent passenger satisfaction outcomes. A model was meticulously crafted by leveraging a decision tree algorithm to discern the substantial variables influencing passenger satisfaction. Simultaneously, the Naïve Bayes algorithm was harnessed to prognosticate forthcoming passenger satisfaction. The findings underscore the diverse facets of the flying experience impacting satisfaction, with both ctree and rpart decision tree algorithms spotlighting critical factors, such as online boarding, inflight entertainment, WiFi service, class, and travel type. The Naïve Bayes algorithm demonstrates around 87% accuracy in predicting passenger satisfaction, underscoring its efficacy in discerning patterns within this complex realm.