bluuebunny/crossref_metadata_2025 huggingface dataset:
Implications for the Pathogenesis and Pathomechanisms of Infantile Idiopathic Scoliosis after Surgery
Authors: Pratt R.K.  , Webb J.K.  , Cummings S.L.  , Burwell R.G.
Published: February 2025

The causative mechanisms in the development of an idiopathic scoliosis are multifactorial and poorly understood. Surgery in progressive early onset idiopathic scoliosis has attempted to manipulate vertebral growth (Roaf 1963) or to control deformity allowing for growth (Luque 1977) or both (Webb). This paper presents a review of a longitudinal radiological study of 24 patients treated operatively for progressive idiopathic scoliosis. All had insertion of Luque trolley instrumentation and 20 had an additional anterior release and convex epiphysiodesis. At 2 years follow-up, 5 were resolving, 9 were maintaining their post-operative correction and 10 were progressing from their initial post-operative correction. At 5 years follow-up, the numbers were 16, 5 and 3 respectively. 6 out of the 7 deteriorating cases had outgrown their Luque trolleys. Factors which are predictive of good results in terms of Cobb angle at 5 years follow-up include a younger age at surgery (p<0.001) and a higher pre-operative apical concave rib-vertebra angle (p<0.005). The amount of spinal growth was not a factor. These results have important implications for the selection of patients for surgery and for the pathogenesis and pathomechanisms of infantile idiopathic scoliosis. The effects of early surgery may facilitate resolution of scoliosis through ‘imprinting’ of corrected spinal morphology on a sufficiently plastic central nervous system. Neuromuscular factors acting on concave ribs are implicated in progression.
Three Dimensional Visualization of Scoliotic Back Surfaces
Authors: Durdle N.G.  , Penner R.  , Raso V.J.  , Hill D.L.
Published: February 2025

A surfacing technique has been developed to provide clinicians with a realistic and accurate representation of the scoliotic trunk. A projection pattern, imposed upon a relatively featureless back, provides a random distribution of discrete three dimensional data points representing the trunk surface. Although measurements can be made from these points, a realistic model is necessary to assess the subjective extent of the deformity and to enhance usage by clinicians. A triangulation technique using connecting lines limited by the data density created a bounded surface mesh that could be quickly rendered and manipulated during analysis. Errors due to data acquisition were reduced by a local median filter. The maximum amount that a data point may be altered was restricted to the measurement error (2 mm), ensuring that the surfacing technique did not significantly alter the back shape. Subsequent Gouraud shading, ambient and diffuse lighting created a realistic surface. The algorithm is O(n), with the implication that doubling the number of data points will only double the processing time. The display, shading, lighting and rotation of a trunk surface with 2000 discrete points took 20 seconds on a 486-66 MHz PC and was three times faster on a IBM RISC 6000 workstation. This surface visualization package has enhanced the overall clinical assessment of the trunk deformity.
Idiopathic Scoliosis and Fluctuating Asymmetry (FA)
Authors: Dangerfield P.H.  , Scutt D.  , Ashton S.  , Manning J.T.  , Dorgan J.C.
Published: February 2025

Asymmetry is a well known physical feature of scoliosis, expressed as the linear asymmetry of the spinal curvature found in the vertebral column and in other skeletal structures such as the skull and limbs. Fluctuating asymmetry (FA) is a deviation from bilateral symmetry in normally bilaterally symmetrical morphological traits. FA gives a composite reflection estimate of the well-being of an individual in their environment. Developmental stability within a species may be measured in two ways, namely by fluctuating asymmetry where there is a small random deviation from normal and by phenodeviants, where there is a marked deviation from normal developmental traits. The marked deviation from normal development found in idiopathic scoliosis, particularly in growth, is an example of the latter. The present study has examined the relationship between scoliosis and FA in a sample of patients with idiopathic scoliosis. The results indicate that a positive relationship between the degree of spinal curvature and FA with severe curvature being associated with a high degree of FA. These findings indicate that a major phenodeviant (idiopathic scoliosis) is associated with general developmental instability.
Mechanical Modulation of Vertebral and Disc Growth Rate
Authors: Stokes I.A.F.  , Spence H.  , Aronsson D.D.  , Kilmer N.  , Gupta D.
Published: February 2025

The tails of growing rats were axially loaded in compression or distraction to investigate the hypothesis that vertebral and disc wedging during growth in spinal deformities is mechanically modulated. Twenty-eight 6-week-old Sprague-Dawley rats were assigned to one of three groups: compression loading, distraction loading, or sham (apparatus applied without loading). Two 0.7mm diameter stainless steel percutaneous pins were passed through two vertebrae and glued to 25mm diameter external ring fixators. Calibrated springs were installed on three threaded rods passing through the rings and compressed with nuts to apply compression or distraction forces between 25% and 75% of bodyweight. Radiographs made at weekly intervals for nine weeks were digitized to measure vertebral and disc growth rates. Loaded vertebrae grew at 68% of control rate for compressed vertebrae, and at 114% for distracted vertebrae (p<0.01 by ANOVA). Rate of change of disc thickness during the experiments was negative for all groups. However, comparison of radiographs before application of load with those made after sacrifice and removal of apparatus showed that compressed discs had reduced thickness averaging 0.49mm, distraction discs had average increased thickness of 0.13mm (p<0.05), and sham discs lost an average of 0.27mm of thickness. Results are compatible with the hypothesis that asymmetric loading of vertebrae and discs promotes scoliosis progression during growth.
Basic Technology of Simulation System for Laparoscopic Surgery in Virtual Environment with Force Display
Authors: Asano Takeo  , Yano Hiroaki  , Iwata Hiroo
Published: February 2025

A basic simulation system for laparoscopic surgery was constructed. The system consists of force display in a virtual environment construction system. Recently, laparoscopic surgery has become popular around the world. However, this operation strategy requires very high dexterity, so that only some medical doctors can use it. Doctors can see the human organs in a three-dimensional environment in the case of ordinary operations. On the other hand, in the case of laparoscopic surgery, doctors can only see a narrow space in a two-dimensional environment on a CRT monitor and tactile information is decreased during operation procedures. We therefore developed a basic technology of surgical simulator for laparoscopic surgery. The focus of our research is the presentation of resistance from virtual organs.
Towards a Novel Augmented-Reality Tool to Visualize Dynamic 3-D Anatomy
Authors: Rolland J.P.  , Wright D.L.  , Kancherla A.R.
Published: February 2025

Using augmented reality (AR) to teach dynamic 3-D anatomy may impart better understanding of bone dynamics during body movement. We are currently developing an AR tool that will allow superimposition and registration of bone structures on real anatomical counterparts of a human subject. This article describes the application, the problems to be solved, and reports on preliminary developmental studies of a first prototype of the tool. Specifically, studies test approaches to simulating real-time dynamic anatomy, and the feasibility in achieving registration of 3-D anatomical bones on their real counterparts. Such a tool will offer several unique advantages over traditional teaching methods and overcome many of their current limitations.
C.A.S.M. and C.A.S.T. — Phase Two
Authors: Ellis Nicola T
Published: February 2025

This paper outlines the second phase of a research project currently being conducted at the University of Central Lancashire. The aim of this second phase is to construct a computer based toolset for clinical audit, based on the structured method (C.A.S.M.) developed during the first phase of the project. A discussion of the validation of the C.A.S.M. and an outline of the toolset is portrayed.
A cooperative methodology to build conceptual models in medicine
Authors: Galeazzi Elena  , Rossi Mori Angelo  , Consorti Fabrizio  , Errera Anna  , Merialdo Paolo
Published: February 2025

We designed a methodology to perform distribute activities on conceptual modelling among cooperating centers. Our methodology assigns responsibilities and tasks and regulates interactions preserving coherence; it passes through the construction of unambiguous paraphrases to make explicit the context within the original sources, and through their compositional representation in an intermediate language. The process is intrinsically iterative, with continuous feedbacks and refinements, alternating analytic view on details and synthetic view on regularities and structures. Our methodology is based on requirements and experience made in the first GALEN project, and was applied in the GALEN-IN-USE project to coordinate modelling activities of three teams of surgeons in Rome with activities of other partners, during the production of an extensive model of surgical procedures.
IDIS-KS: an Intelligent Drug Information System as a Knowledge Server
Authors: Vlahavas I.  , Pomportsis A.  , Sakellariou I.
Published: February 2025

Expert System technology in combination with other technologies such as Networks and Data Base systems can prove to be a valuable tool for medical experts, providing decision support and information services, and therefore facilitating and improving their everyday tasks. IDIS-KS described in this paper, is an consultation and information system dedicated to deliver drug information and suggestions about possible treatments to medical practicioners in the National area of Greece.
PRONET Services for Distance Learning in Mammographie Image Processing
Authors: Costaridou L.  , Panayiotakis G.  , Efstratiou C.  , Sakellaropoulos P.  , Cavouras D.  , Kalogeropoulou C.  , Varaki K.  , Giannakou L.  , Dimopoulos J.
Published: February 2025

The potential of telematics services is investigated with respect to learning needs of medical physicists and biomedical engineers. Telematics services are integrated into a system, the PRONET, which evolves around multimedia computer based courses and distance tutoring support. In addition, information database access and special interest group support are offered. System architecture is based on a component integration approach. The services are delivered in three modes: LAN, ISDN and Internet. Mammographie image processing is selected as an example content area.
A second generation of terminological systems is coming
Authors: Mori Angelo Rossi  , Consorti Fabrizio  , Galeazzi Elena  , Merialdo Paolo
Published: February 2025

Diverse achievements by recent computer-based terminological systems are outlining a new generation of systems (ie. a “second generation”). We collected the relevant features of various advanced terminological systems and we systematized these features into four components of a unique framework. We review a set of systems according to our framework, and we discuss how standardization activities can support the evolution of computer-based terminological systems towards a complete set of new performances.
A 3D ultrasound scanner : real time filtering and rendering algorithms
Authors: Cifarelli D.  , Ruggiero C.  , Brusacà M.  , Mazzarella M.
Published: February 2025

The work described here has been carried out within a collaborative project between DIST and ESAOTE BIOMEDICA aiming to set up a new ultrasonic scanner performing 3D reconstruction . A system is being set up to process and display 3D ultrasonic data in a fast , economical and user friendly way to help the physician during diagnosis. A comparison is presented among several algorithms for digital filtering , data segmentation and rendering for real time , PC based , three-dimensional reconstruction from B-mode ultrasonic biomedical images .Several algorithms for digital filtering have been compared as relates to processing time and to final image quality . Three-dimensional data segmentation techniques and rendering has been carried out with special reference to user friendly features for foreseeable applications and reconstruction speed.
Studies of Responsiveness in the R-EGFR and Rcerb-B2 Oncogenes Spaces: a Customized Application for Thyroid Lesions
Authors: Šiška Arijan  , Babić Ankica  , Pavešić Nikola
Published: February 2025

Among verity of diagnostic approaches suitable for clinical analysis of thyroid lesions, the two oncogenes (R-EGFR and Rcerb-B2) are believed to be of discriminative power. In a retrospectively collected patient material we have defined different lesion types (normal tissue, benign and malignant tumours). Those were taken as class definitions in analysis performed to assign discriminating performance. Standard multivariate statistics has not performed satisfactory partly due to the data distribution and partly due to presence of the noise. Therefore we have developed a method for the classification purpose, which was based on principle of minimising generalised classification error. Results of the separation between carcinoma and normal tissue reached accuracy 70%, other classification attempts ended up in poor results. In general, misclassifications could be explained with the data quality (noise) and, when it came to benign lesions, with responsiveness of the oncogenes to tumour tissues.
The Use of an Expert System of Composite Risk Factors in Breast Cancer Screening
Authors: Tsouskas LI  , Liaros A  , Tzitzikas J  , Pantelis P  , Capizzello A  , Papadopoulos LS
Published: February 2025

Mass Screening seems to be the only promising way to discover breast cancer patients at an early and more curable stage and a positive method improving the cost-effectiveness and compliance of mass screening is the use of prognostic factors, to identify the high-risk group, who alone then would be screened. In a 200 women sample, who had undergone screening for breast cancer with clinical examination and bilateral mammography, we calculated the Composite Risk Factors of six Characteristics (C6RF), which are family history for breast cancer, pregnancy history, menstual history, history of cystic breast disease, history of regular breast clinical or self-examination and presence or not of breast lump, using an expert system in IBM-compatible personal computer. In these cases the average C6RF was 0.18 (SD±0.19) in low-risk group and 2.61 (SD±4.76) in high-risk group and all cases with C6RF values higher than 0.56 were put in the high-risk group. Under these conditions, the sensitivity of the C6RF method, in discovering breast cancer, was 90% and the specificity 81.5% and the C6RF method was proved to be clinically valuable in identifing the high-risk group and controling breast cancer.
Implementing Data Privacy and Security (The Slovenian Experience)
Authors: Markota Mladen  , Raič Gorazd
Published: February 2025

Data protection is carried out in two steps. The legislation covers data privacy in general as well as its projection in health care. Its purpose was to leave no personal data undefined within the national health care system. The regulations deal with procedures and anticipated corrective actions, rendering a so-called “organisational prescription”. Its purpose was to assure data security through an appropriate information system.
Human Factors Consideration in Clinical Applications of Virtual Reality
Authors: Lewis Christopher H.  , Griffin Michael J.
Published: February 2025

Virtual reality environments have many potential applications in medicine, including surgical training, tele-operated robotic surgery, assessment and rehabilitation of behavioural and neurological disorders and diagnosis, therapy and rehabilitation of physical disabilities.
Synapses in the Context of Healthcare Information Systems
Authors: Grimson William  , Sottile Pier-Angelo
Published: February 2025

The Electronic Healthcare Record will increasingly lie at the heart of the Healthcare Information Systems of the future, and the ability to share safely and meaningfully patient records between Hospital Information Systems depends crucially on an agreed architecture for EHCR. This paper describes the approach to providing access to Federated Healthcare Records as proposed by Synapses, a pan-European project funded under the EU Health Telematics Programme, through the use of a record server. The positioning of this server within the Healthcare Information Systems Architecture is discussed together with some suitable candidate technologies for implementation.
A Knowledge-Based Decision Support System for Prevention and Treatment of Pressure Ulcers
Authors: Zielstorff R.D.  , Barnett G.O.  , Estey G.  , Hamilton G.  , Vickery A.  , Welebob E.  , Fitzmaurice J.B.  , Shahzad C.
Published: February 2025

As part of a research project intended to provide problem-based knowledge to clinicians at the point of care, we have developed a system that supports the nurse's development of patient-specific, guideline-based treatment plans for patients who have pressure ulcers or are at risk for developing them. The system captures coded data about assessment, diagnosis and interventions using a point-and-click interface. Knowledge is accessible to the user via: 1) hypertext links from the data entry screens; 2) explicit entry into an indexed version of the guideline; 3) imbedded knowledge-based rules that critique the diagnosis and offer guidance for treatment; and 4) explicit entry into interactive algorithms. The system has been implemented experimentally on one care unit at our hospital, where its impact will be assessed in comparison with a control unit. Data on 113 patients were entered during the 21-week experimental period. The system is being evaluated for its instructional adequacy, its impact on clinicians' decision-making and knowledge, and on processes of care. Users' perceptions of the system are also being evaluated. Dissemination issues in the context of today's health care environment are addressed.
Using Nursing Resources on the Internet
Authors: Silva M.A.  , Lopes M.H.
Published: February 2025

We have been developing the Nursing Resources of the Nursing Department of the Brazilian Virtual Hospital using HTML language and navigational tools. Our objective has been to create connections with a wide range of nursing information which is available on the Internet. There will be constant updating of the program in order to meet the objectives of this project
Developing Informatics as a Discipline
Authors: Turley J.P.
Published: February 2025

Informatics is developing in all of the disciplines related to healthcare. There are many aspects to informatics development which frequently appear to be unrelated and to lack cohesion. This paper builds on the development of a model for nursing informatics and proposes how the components of that model can interact to provide an outline for the development of informatics as a discipline. A understanding of the disciple allows us to organize the existing research and more importantly to understand the areas where research is lacking as the discipline is evolving.
An electronic data card for pregnancy and delivery
Authors: Sicurello F.  , Cencini F.  , Zucchi C.  , Acaia B.  , Rossi G.  , Bestetti P.
Published: February 2025

This work concerns itself with the development of automatic procedures which are able to manage a medical record of pregnant women and to improve the data exchange using smart card technology, in order to make the health services offered by clinical settings, specialists, general practitioners, family specialists in the obstetricgynaecological area, more efficient.
Health smart cards - Security Server and Healthcare Information System
Authors: Nisand G.  , Brunetta V.  , Brézillon R.  , Stackler A.  , Boux O.  , Zimmerlé G.  , Roeslin N.
Published: February 2025

The integration of Professional Health Smart Card Hospital Information System will allow the structuring of computer systems in the medical field, and support of healthcare networks by improving and standardizing security in data exchanges in the health domain. It is the way choose by the French government. The PHSC experiment in our establishment will take place in April 1997. The option of acquiring an industrial security server will facilitate the integration of other HIS. It will also allow a security standardisation and will promote the interoperation between systems.
Project “MACHA” - health card pilot apppplication in the Czech Republic Progress and development
Authors: Neuwirt K.  , Damborsky P.  , Ochozka J.  , Trpisovsky T.
Published: February 2025

Since 1995 there are intensive activities in the health cards area in the Czech Republic. An experimental application is running since 1996 in one district of the CR. With support of the EC Phare Programme a plan was created for extension and continuation of the project. This experiment is one road to the Information Society in the health sector in this country.
Virtual Medical Trainer
Authors: Kizakevich Paul N.  , McCartney Michael L.  , Nissman Daniel B.  , Starko Ken  , Smith N Ty
Published: February 2025

The Virtual Medical Trainer (VMET) combines multimedia sound and graphics with physiological engines, medical-procedures databases, and 3-D patients to produce an interactive environment that can mimic the cognitive pre-hospital assessment and care demands of a real emergency. VMET uses a reconfigurable component software and training framework that allows a uniform user interface, ease of increasing training complexity, and expansion of the software components. VMET provides an opportunity to experience a range of trauma scenarios prior to the challenge of an actual trauma situation.
VIDEOCONFERENCING AS A MEDICAL EDUCATIONAL TOOL: FIRST EXPERIENCE IN ARGENTINEAN PUBLIC HOSPITAL
Authors: Altrudi Rodolfo  , Eurnekian Alberto  , Gandsas Alex  , Silva Yvan  , Silvestri Victoria
Published: February 2025

Authors present their experience with first medical videoconferencing program developed in a public Argentinean hospital. Both modalities –room and desktop videoconferencing– were used. The program was exclusively used for educational purposes.
FORMATIVE DESIGN OF A VIRTUAL LEARNING ENVIRONMENT
Authors: Dev Parvati  , Pichumani Ramani  , Walker Decker  , Heinrichs W.LeRoy  , Karadi Chandu  , Lorie William
Published: February 2025

Current technology for 3D visualization, modeling and interaction allows the construction of attractive virtual environments for study of anatomy, surgery and other biomedical fields. The formative methodology for designing such environments is uncharted, but necessary before committing to large scale development. We present one such methodology undertaken during the design of a learning environment for biology for high school and middle school students. We expect to extend this design methodology to the development of environments for the teaching of medical subjects.
INTERNATIONAL SURGICAL TELEMENTORING: OUR INITIAL EXPERIENCE
Authors: Lee Benjamin R.  , Caddedu Jeffrey A.  , Janetschek Gunter  , Schulam Peter  , Docimo Steven G.  , Moore Robert G.  , Partin Alan W.  , Kavoussi Louis R.
Published: February 2025

Introduction: Telesurgical laparoscopic telementoring has successfully been implemented between the Johns Hopkins Bayview Medical Center and the Johns Hopkins Hospital in 27 prior operations. In this previously reported series, telerobotic mentoring was achieved between two institutions 3.5 miles away. We report our experience in performing two international surgical telementoring operations.
Good Practice in Multimedia Courseware Development
Authors: Schulz Carl
Published: February 2025

The main goal of the European TALENT/ESPRIT project is to create a generic environment for developing multimedia courseware. The first phase of the project concerns itself with developing conversion tools for converting text based course material into multimedia format. The second phase of the project adds network support to the courseware in the form of the network tutoring and networked supply chain support.
Nursing Informatics Education for Advanced Nursing Practice
Authors: Goossen William TF  , Kroesen Jan  , Niehuis Marian
Published: February 2025

This paper describes how nursing informatics content will be integrated into the education of Advanced Nursing Practitioners at Masters level. Changes in health care, especially the need to deliver evidence based nursing care and the growing amount of health data, information and knowledge, require well educated Advanced Nurse Practitioners to lead the nursing profession. The nursing informatics content for this level of nursing education is described and compared with national and international curriculum guidelines, including Nightingale work.
The Electronic Patient Record as a Guarantor of Personalised Mental Health Care
Authors: Mooney Monica  , Barry Siobhan  , Draper Ronald
Published: February 2025

A provider of mental health services on multiple sites experienced major problems of availability with traditional paper records and commenced development of an electronic patient record (EPR) and clinical information system in order to provide integrated, real time patient based information. The development process, including clinical and technical considerata is described in order to draw conclusions about the ways in which EPR’s can be a vehicle for change from traditional practice to the multidisciplinary, community based practise developments of recent years. The system can generate information for continuous quality improvement, service planning, and philosophies of care. The key requirements of good record systems are established and the inability of paper records to meet them. In contrast the electronic record has demonstrated ability to guarantee personalised, quality, mental health care.
Transporting an Electronic Patient Record System Across International Boundaries-The Lessons Learnt.
Authors: Hannan Terry J
Published: February 2025

This paper will outline the tasks involved, completed and not achieved over an eight year period involving the implementation of the Johns Hopkins Oncology Center Information System (OCIS) in an oncology department of a secondary / tertiary care hospital in Australia.
Telematics In The Neonatal ICU And Beyond: Improving Care, Communication and Information Sharing.
Authors: Gray James  , Jones Peter C.  , Phillips Michele  , Veroff David  , Safran Charles
Published: February 2025

In October of 1998, the Beth Israel-Deaconess was awarded one of 19 contracts from the National Library of Medicine (NLM) to develop, implement and test a telemedicine application to support the care of Very Low Birth Weight Infants. This project is the only one to focus on the care of newborns. We believe that this project will provide a new national approach to managing the care of high-risk newborns by leveraging evolving communication technology.
Medical Counseling through Computer Communication Networks
Authors: Yoo Sun-Mi  , Lee Haeng  , Kim Soo-Young
Published: February 2025

Medical counseling on the computer communication network will be used increasingly with wide-ranging concern of people about health and strengthening the role of medical care as social service. This study was designed to explore main problems/issues of network counseling and to suggest future prosperity of medical counseling. We analyzed questions and answers in the Association of Family Medicine in the KETEL since 1991, Medical counseling corner which is in the UNITEL since 1996, and Online counseling in VIRTUAL HOSPITAL since 1996, and classified the reason for encounter, systematic classification of counseling by ICPC, and answer content. Inquiry about symptoms was the most common reason for encounter, followed by treatment and prevention strategies, detailed information about diseases, and inquiry about laboratory tests. Systematic classification by ICPC showed common problems of skin, digestive, musculoskeletal and general & unspecified, which was a different look compared with common problems in primary care. The answer content presented a different look among three groups. Common answers were mainly to offer medical information, to recommend visiting a doctor, and to provide self-care remedies.
Simple Models for Estimating Dementia Severity Using Machine Learning
Authors: Shankle W.R.  , Mania Subramani  , Dick Malcolm B.  , Pazzani Michael J.
Published: February 2025

Estimating dementia severity using the Clinical Dementia Rating (CDR) Scale is a two-stage process that currently is costly and impractical in community settings, and at best has an interrater reliability of 80%. Because staging of dementia severity is economically and clinically important, we used Machine Learning (ML) algorithms with an Electronic Medical Record (EMR) to identify simpler models for estimating total CDR scores. Compared to a gold standard, which required 34 attributes to derive total CDR scores, ML algorithms identified models with as few as seven attributes. The classification accuracy varied with the algorithm used with naive Bayes giving the highest. (76%) The mildly demented severity class was the only one with significantly reduced accuracy (59%). If one groups the severity classes into normal, very mild-to-mildly demented, and moderate-to-severely demented, then classification accuracies are clinically acceptable (85%). These simple models can be used in community settings where it is currently not possible to estimate dementia severity due to time and cost constraints.
A Hypermedia-based Medical Records Management System
Authors: Laforest Frédérique  , Frénot Stéphane  , Flory André
Published: February 2025

This article presents a new way to manage computerized medical records, based on a totally-hypermedia system. As a matter of fact, the classical use of a database limits the necessary variability of the medical record, in function of both the patient profile and the care practitioner habits. The system we propose is based on a hospital Intranet, and on the XML language. This language allows the definition of semantic tags in hyperdocuments, and thus information retrieval is ensured through semantic tags indexation.
A Concept Model for the Automatic Maintenance of Controlled Medical Vocabularies
Authors: Rodriguez Juan  , Maojo Victor  , Crespo Jose  , Fernandez Isabel
Published: February 2025

A controlled medical vocabulary is a fundamental requirement in a range of medical informatics applications. Large vocabularies development and maintenance is labor intensive and costly. Maintainers of medical vocabularies need appropriate tools to do their work correctly. In this paper, we describe our concept model for a controlled medical vocabulary. We present how this model can check vocabulary consistency. We propose a set of tools in a distributed environment, which permits edition, visualization and maintenance of medical terminologies.
Use of Project Ontologies and Terminology Servers to Support Software Engineering
Authors: Bång Magnus  , Eriksson Henrik  , Timpka Toomas
Published: February 2025

Complex medical software imposes new requirements on the methods and tools used for maintenance. Appropriate maintenance tools can increase software reliability and quality by providing means to trace dependencies among software artifacts for reducing unexpected impacts in software caused by software changes. We have used the GRAIL concept-representation language for medical terminologies to build a project ontology that models relationships among software artifacts. Our approach involves modeling of the terminology used in software projects, which enables us to describe, classify and relate individual software artifacts. A networked repository accessible to the entire software development staff stores the conceptual model, source code and associated documents. We present an architecture for a maintenance tool, and show how developers can use GRAIL to build a project ontology.
VM-in-Protégé: A Study of Software Reuse
Authors: Park John Y.  , Musen Mark A.
Published: February 2025

Protégé is a system that encompasses a suite of graphical tools and a methodology for applying them to the task of creating and maintaining knowledge-based systems. One of our key goals for Protégé is to facilitate reuse on new problems of components of previously developed solutions. We investigated this reusability by applying preexisting library components in the Protégé system to a reconstruction of VM, a well-known rule-based system for ventilator management. The formal steps of the Protege methodology—ontology creation, problem-solving method selection, knowledge engineering, and mapping-relation instantiation—were followed, and a working system with much of the reasoning capability of the original VM was created. The work illuminated important lessons regarding aspects of component reusability.
Automated Acquisition of Rules from Clinical Databases and its Evaluation
Authors: Tsumoto Shusaku  , Tanaka Hiroshi
Published: February 2025

This paper presents an approach to induction of rules from databases using rough set model. The system was evaluated on three clinical databases, and induced results were compared with other conventional rule induction methods and medical experts' rules. The results show that the introduced results outperforms other methods, but that the description length of induced rules is a little short, compared with that of experts' rules, which suggests that experts' rules are combination of different kinds of reasoning, rather than simple classification.
The Economic Implications of Users Willingness to Increase Knowledge Capital in Health Informatics
Authors: Vimarlund Vivian  , Timpka Toomas  , Hallberg NikIas
Published: February 2025

Objective: To develop an economic model ofhealth care professionals 'demand for knowledge capital in health informatics.
Investigating a Concept-Based Tool to Enhance the Process of Curriculum Development: An Example for Healthcare Education
Authors: Alpay Laurence  , Giffen Randy
Published: February 2025

This paper reports on a first exploration carried out in the CoMET (COncept Modelling Environment for Teachers) project to investigate the educational potential of a concept-based toolkit developed in the GALEN project. In particular, on whether such tools can offer a basis to support and enhance healthcare curriculum development. We first adapted part of the toolkit by developing a front-end user friendly interface to access the conceptual knowledge. We then collected data from an empirical study. Preliminary results suggest that the concept-based approach of the CoMET tools is viable and has several potential benefits for educational activities. Directions for further work in the use ofthe concept-based tool for teaching as well as learning are also discussed.
Continuous Quality Improvement through use of Perinatal Clinical Record and Agustina Database
Authors: Manetti Graciela  , Rodas Eduardo  , Morici Pablo  , Fernandez Roberto Gallino  , Tonietto Angel  , Oliveri Nora
Published: February 2025

This paper reviews the development of the field of medical informatics in Latin America. It also describes the results of a computer-based data management system, named AGUSTINA, which is comprised of maternal and infant data on 7570 deliveries that occurred between June, 1990 and December, 1996 in a hospital in the surroundings of Buenos Aires, Argentina. These data were fundamental for the instrumentation of preventive community-oriented activities in the area. Finally, this paper describes recommendations for future actions in the area of medical informatics in Latin America.
Happy Birthday DIOGENE: a Hospital Information System Born 20 years ago
Authors: Borst F.  , Lovis Ch.  , Thurler G.  , Maricot P.  , Rossier Ph.  , Revillard Cl.  , Scherrer J.R.
Published: February 2025

Since its birth in 1978, DIOGENE, the Hospital Information System of Geneva University Hospital has been constantly evolving, with a major change in 1995, when migrating from a centralized to an open distributed architecture.Since a few years, the hospital had to face health policy revolution with both economical constraints and opening of the healthcare network. The Hospital Information System DIOGENE plays a significant role by integrating four axes of knowledge
Annex III: List of New Terms
Authors: Ferrer-Roca O.  , Sosa-Iudicissa M.
Published: February 2025

The following list of terminology include terms not appearing in the book or new terms that might be of use in some Telemedicine aspects. It is not a complete glossary and only try to help with the numerous abbreviations and new names appearing in the market.
The Handbook of Medical Informatics and its Web Site
Authors: van Bemmel Jan H.
Published: February 2025

Since the new Handbook of Medical Informatics was published in 1997, a p-version of a web site (“MI WEB”) has been opened that supports the teaching of the Handbook. MI Web refers to the text of the full Handbook, using an extensive Glossary that is shared by both the paper Handbook and the web site. New material for teaching will continuously be added to the MI Web, realizing that the field of health informatics is progressing exponentially, that the teaching of medical informatics is of great importance for students in medicine and health care, and that these students will be the health professionals of the future. Training in medical informatics is also of value for practicing clinicians who are overwhelmed by the avalanche of systems that are available on the market.
Simulation Model for Educating the General Public for the AIDS Epidemic
Authors: Verginis Ilias  , Diomidous Marianna  , Mantas John
Published: February 2025

In the Health field, there is an increasing need to give the Health professional the opportunity to experiment on real situations without necessarily having to be in contact with the patient. In order for this to be achieved, there must be a virtual reality representation via a safe and user friendly system, such as a computer. This means that by using Simulation and modelling techniques new models have to be constructed which will portray the reality. The scope of this paper is to present a Simulation Model and Practical for Educating the General Public for the AIDS Epidemic. The model and the practical were developed by using the tools and applications created under the COAST project.
Simulation of CD Surgery on a Personalized Finite Element Model: Preliminary results
Authors: Le Borgne P.  , Skalli W.  , Lecire C  , Dubousset J.  , Zeller R.  , Lavaste F.
Published: February 2025

The aim of this study is to simulate correction of scoliosis using a finite element model in order to predict 3D correction with CD technique. The geometry of the 3D finite element model is personalized as well as the mechanical behavior. Hence each step of CD surgery is simulated : patient on the traction table, fixation of screws and hooks, linkage between rod and hooks and at last the rotation maneuver. Principles of validation is presented using per-operative measurements. Feasibility of the method is demonstrated on one given patient. First results are promising and would allow the surgeons to objectively analyze various strategies or techniques.
3D Correction of Trunk Deformity in Patients with Idiopathic Scoliosis Using Cheneau Brace
Authors: Rigo M
Published: February 2025

In this retrospective series, 49 patients who had progressive idiopathic scoliosis, were studied to determine the effect of Cheneau brace treatment on back shape by means of the Formetric system. Lateral deviation (rms) and Rotation (rms) decreased significantly. In 37 patients, lateral shape of the spine was improved or preserved. This study demonstrate that the Cheneau brace, combined with physiotherapy, seems to produce a maintained 3D correction effect on back shape.
Cardiac Control and Cardiorespiratory Coordination during Sleep and Wakefulness
Authors: Unbehaun Axel  , Patzak Andreas  , Mrowka Ralf  , Persson Pontus B.
Published: February 2025

Since chaotic phenomena of heart rate have been observed, investigations by time series analysis have been focused on the non-linear dynamics of the cardiac control system. Without the necessity to understand the functional structures of the complex regulatory network that controls heart rate, non-linear methods are a useful approach to characterize the processes inside this black box. We applied established linear and non-linear methods to obtain comprehensive information regarding heart rate control and its relation to the respiratory system. To study normal regulation under various conditions, 42 healthy children were investigated during different vigilance stages. The parameters of heart rate power spectra were estimated, the linear intensity of cardiorespiratory coupling was concluded from the coherence spectra. As to non-linear properties of heart rate, the largest Lyapunov exponents as well as the correlation dimension were determined. Similarly, the correlation dimension of the respiratory signals was evaluated. The total power of the heart rate spectrum was found to be greatest during REM, it decreased during wakefulness and was low in nonREM-sleep. These variations are mainly accounted for by low frequency power. The “complexity” of heart rate, as indicated by the correlation dimension, is diminished during sleep phases, whereas the Lyapunov exponents are less affected. The cardiorespiratory coherence is strongly modulated by vigilance with an increase during nonREM and lowest values during REM. The complexity of respiration was also affected by vigilance. A different behavior of heart rate complexity was found during REM-phases. Concluded from spectral analysis, we suggest a specific setting of autonomic heart rate regulation for each vigilance stage. A low dimensional deterministic chaos is present in heart rate time series. More independent control loops were found to be active during wakefulness. Revealed by parameters of the non-linear dynamics, different stages of vigilance determine different operating points in the cardiorespiratory coordination.
Consensus Building out of many German Translations
Authors: Tackenberg Peter
Published: February 2025

In 1997 the DIHNR initiated a project to develop a complete translation of the ICNP into German language. This translation was based on three previous translations with an an emphasis on consensus building in analysed translation differences. The aim of the project was to promote and support the process of coming to an agreement about concepts and contexts of nursing phenomena and nursing interventions.
Explaining the ICNP by the Means of a Poster
Authors: König Peter  , Etzel Birgit  , Eiden Sr.Marie-Theres  , Pauen Anne  , Salrein-Hahn Gabriele  , Werbke Sebastian  , Wolf Margit
Published: February 2025

The Nursing Diagnosis Workgroup at the Tumor Biology Center works on an answer how to implement ICNP. Primary aim was to get to know ICNP and to teach nurses about it. Looking for a reasonable way to clarify the complex structures the idea of a poster with an overall view seemed promising. In this visual way it was relatively easy to explain the construction of ICNP to the nurses. Today, the poster is used for presentations and always incites intense discussions.
Telepathology in Neurosurgery
Authors: Abbasi H.R.  , Weigel R.  , Sommer C.  , Schmiedek P.  , Kiessling M.
Published: February 2025

In most tumor cases of neurosurgery, we need to have a rapid section diagnostic of the tumor during the course of surgery. When we have received the results that diagnose the exact dignity of the tumor, we devise the operation strategy for the continuing course of surgery. The tissue sample is sent by taxi to the pathological institute in Heidelberg. It takes approximately 45-60 min until we receive the results by telephone.
Dynamic Volume Texture Mapping and Model Deformation for Visually Realistic Surgical Simulation
Authors: Lin Wei-te  , Robb Richard A.
Published: February 2025

For computer assisted surgical simulation to be effective, objects in the simulated environment should respond to the user’s actions dynamically with correct visual information. This includes dragging and cutting that cause changes in geometry, topology and appearance. Geometric object representation can be manipulated intuitively in real-time but does not preserve interior information. Volumetric data representation, on the other hand, preserves volume content but direct manipulation is compute-intensive. 3-D texture mapping provides an alternative in representing volumetric information. We present a surgical simulation system based on geometric models that allows interactive deformation and incision of objects while displaying correct volumetric information corresponding to these changes. This is accomplished by dynamic 3-D texture mapping. This method can be applied to anatomical data and patient CT and MR images to facilitate data/patient specific surgical simulations.
DEVELOPMENT OF A ROBOTIC NAVIGATION SYSTEM FOR NEUROSURGERY
Authors: Tseng Ching-Shiow  , Chung Chi-Wei  , Chen Hung-Huei  , Wang Shih-Shing  , Tseng Han-Ming
Published: February 2025

This paper presents a robotic navigation system for image-guided neurosurgery, which can be applied to the treatment of Parkinson’s disease and biopsy of brain tumor. The system integrates a computer for real-time display of brain anatomy, a magnetic tracking device for measuring the positions and orientations of surgical instruments, and a robot manipulator for guiding surgical instruments to the preplanned positions and orientations. The computer display of brain anatomy offers a convenient tool for surgeons to diagnose brain disease and to plan safe surgical paths; while the tracking device assists the robot manipulator to automatically guide surgical instruments to the preplanned direction. The registrations among the tracking device, the image system, and the robot are completed on the base of coordination mappings of external markers. An experiment of using a skull model for simulating a robotic biopsy of brain tumor has been done to verify the performance of the navigation system. The result shows that the system can accomplish a positioning accuracy around 2 mm.
Towards a Methodology for Developing and Implementing Best Practices in Telehealth and Telemedicine
Authors: Picot Jocelyne
Published: February 2025

One objective of the growing telehealth and telemedicine literature base is to inform potential adopters and raise their awareness through pilot projects. However, pilot studies often fail to create sustainable solutions because certain conditions are needed for long term success:
Theory of Use behind Telehealth Applications
Authors: Lehoux Pascale  , Sicotte Claude  , Lacroix André
Published: February 2025

A variety of telehealth applications have been implemented throughout the industrialized world. Given that telehealth has yet to become routine in the practices of physicians, the impact of such applications on health care management remains difficult to identify. Only by becoming integrated into the ‘normal practice’ of clinicians can telehealth facilitate smooth communications in health care delivery processes.
Results of European Projects Enabling Secure Regional, National and International Health Care Networks
Authors: Blobel Bernd
Published: February 2025

Based on the work of the ISHTAR, the TRUSTHEALTH1, the EUROMED- ETS and the MEDSEC project funded by the European Commission, the synergetic results of these different projects in providing a security infrastructure for the test environment of an oncological network will be demonstrated.