The use of hydrolyzed formulas as a method of correction of feeding and clinical rehabilitation of infants with atopy signs
Authors: Bezruk Volodymyr Volodymyrovych ,   Department of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine,   * Corresponding Author: Volodymyr Volodymyrovych Bezruk, Department of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine. E-mail: vvladimyrbezruk@gmail.com, Godovanets Oleksii Serhiiovych ,   Department of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine, Buriak Oleksandr Hryhorovych ,   Department of Pediatrics, Neonatology and Perinatology Medicine, Bukovinian State Medical University, Chernivtsi, Ukraine, Voytkevich Nina Ivanivna ,   Department of Foreign Languages, Bukovinian State Medical University, Chernivtsi, Ukraine, Makarova Olena Victorivna ,   Department of Patient Care and Higher Nursing Education, Bukovinian State Medical University, Chernivtsi, Ukraine, Yurkiv Oksana Ivanivna ,   Department of Patient Care and Higher Nursing Education, Bukovinian State Medical University, Chernivtsi, Ukraine, Sheremet Michael Ivanovych ,   Department of Surgery No.1, Bukovinian State Medical University, Chernivtsi, Ukraine, Bilookyi Oleksandr Vyacheslavovych ,   Department of Surgery No.1, Bukovinian State Medical University, Chernivtsi, Ukraine, Hresko Mykhailo Mykhailovich ,   Department of Surgery No.1, Bukovinian State Medical University, Chernivtsi, Ukraine, Velia Mariya Ivanivna ,   Department of Pharmacy, Bukovinian State Medical University, Chernivtsi, Ukraine, Yurniuk Svyatoslava Vasylivna ,   Department of Pharmacy, Bukovinian State Medical University, Chernivtsi, Ukraine, Hresko Maryna Dmytrivna ,   Department of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine, Bulyk Tetiana Sergiivna ,   Department of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine, Rynzhuk Larysa Vasylyvna ,   Department of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine, Maksymiv Oleh Olehovich ,   Department of Prosthetic Dentistry, Bukovinian State Medical University, Chernivtsi, Ukraine, Shkrobanets Igor Dmytrovych ,   Department of Medical and Organizational Management, National Academy of Medical Sciences of Ukraine, Kiev, Ukraine
Published: May 2023

Our study showed that in formula-fed babies, the use of mixture X (containing 2'-FL (2'-fucosyllactose) – a type of milk oligosaccharide, as well as carefully studied Bifidobacterium lactis, DHA, ARA, and nucleotides) as the main product for feeding could ensure children's body with all the necessary nutrients. Furthermore, it can minimize the progression of clinical signs of atopic dermatitis and reduce the use of drugs. In addition, there was an improvement in height and weight parameters, proportional development of the child (p<0.05), an increase in the number of erythrocytes (erythrocytes), hemoglobin (Hb), mean cell volume (MCV) (p<0.05), a decrease in the number of leukocytes (WBC) (p<0.05), and leveling of skin signs of atopic dermatitis (AD) (according to SCORAD a decrease from 32.8±5.5 to 16.1±2.2, p<0.05). Based on these results, it is possible to recommend using mixture (X) with a preventive and rational purpose as a product of artificial feeding of children with a hereditary predisposition to allergies.