bluuebunny/crossref_metadata_2025 huggingface dataset:
Interaction studies of chiral non-steroidal anti-inflammatory drugs with HSA protein using capillary electrophoresis frontal analysis and electrokinetic chromatography
Authors:   , Khulu Sinegugu
Published: August 2021

Human Serum Albumin (HSA) predominantly found in the blood plasma proteins, acts as a carrier for many drugs. In the present work binding interactions of eight arylpropionate non-steroidal anti-inflammatory drugs (NSAIDs) were studied with Human Serum Albumin HSA using Capillary Electrophoresis (CE) under physiological conditions. The concentration of HSA was kept constant (525 μM) whereas the drug concentrations were varied between 50-300 μM in each case. The Frontal analysis (FA) and Capillary Zone Electrophoresis (CZE) modes of CE were applied together with a mathematical modelling of the experimental results with a view to obtaining pharmacokinetic properties of each drug. The binding order of the drugs to HSA were established with the three methods together with the mathematical approach. Our studies revealed the presence of more than one binding sites for some of the available drugs. Additionally, molecular docking studies were conducted to establish the binding conformations of drugs in the binding pocket of the HSA. A very good correlation between the computed binding energies (docking) and the experimental binding constants were observed throughout this study. The logK values for all eight drugs were ranging from 3.37 - 4.56 for FA, 3.16 – 4.39 for CZE, and 3.48 – 5.30 for computational studies.
Ester. Ópera bíblica en tres actos. Partitura general
Authors:   Facultad de Artes y Humanidades, Universidad de los Andes, Ponce de León José María , Torres Rondy
Published: August 2021

Durante la segunda mitad del siglo XIX, diferentes compañías viajeras europeas presentaron óperas y zarzuelas en Bogotá. José María Ponce de León (1845-1882), compositor bogotano, escribió tres grandes obras líricas: dos óperas sobre libretos del poeta Rafael Pombo, Ester (1874) y Florinda (1880), y la zarzuela El castillo misterioso (1876). Considerada como la primera ópera escrita por un compositor colombiano, Ester, ópera bíblica en tres actos fue estrenada en 1874 en el Coliseo Maldonado de Bogotá por una compañía italiana. Desde entonces, y pese a la revisión de la obra por parte del compositor, la ópera nunca volvió a ser representada y cayó en el olvido. La presente edición crítica, basada en los manuscritos autógrafos conservados en diferentes archivos en Bogotá, es la primera edición integral de esta ópera colombiana. Esta publicación se hace junto con la reducción para canto y piano.
Smart Home IoT Sensors: Principles and Applications A Review of Low-Cost and Low-Power Solutions
Authors: Gazis Alexandros , Katsiri Eleftheria
Published: August 2021

Computer scientists and researchers have focused their efforts on advancing from traditional computing techniques to the use of “Industry 4.0”. Specifically, this term includes breakthroughs in numerous fields, including manufacturing, Artificial Intelligence, machine learning and data science. Additionally, emphasis is placed on the so-called “Internet of Things”, i.e. the development of interconnected devices capable of communicating and processing information, mainly from sensory networks. This article presents electronic devices used for home automation. Specifically, it presents different types of residential sensors which can transform a traditional house to a “smart home”. Furthermore, it reviews their possible uses, such as for ventilation, security and temperature monitoring. Lastly, for each of the sensors, the article recommends low-cost sensory devices to set up affordable home automation projects, such as an Arduino and a Raspberry Pi.
AI-Based Virtual Teacher Assistants
Authors: Бесшапошников Н.О. , Дьяченко М.С. , Леонов А.Г. , Мащенко К.А.
Published: August 2021

Современное образование находится на рубеже цифровой эпохи в преподавании, когда повсеместно внедряются новые методы обучения с использованием передовых информационно-коммуникационных технологий для дистанционных форм общения между педагогом и слушателями, автоматизации образовательного процесса с применением нейронных сетей и машинного обучения. Разрабатываемые цифровые образовательные среды и платформы не только позволяют учителю готовить и предоставлять школьникам и студентам учебный материал в удобной цифровой форме, которые доступны им в любом месте земного шара через сеть Интернет, но и существенно увеличивают нагрузку на преподавателя ростом объема необходимого для подготовки занятий образовательного контента. При этом преподаватель на дистанционной форме обучения фактически вынужден находиться круглые сутки на связи со своими слушателями. Использование цифровых образовательных сред с автоматизированной проверкой заданий позволяет освободить педагога от части рутинной работы. Другая возможность состоит в использовании в курсах виртуальных ассистентов преподавателя чат-ботов, обученных с помощью нейросетевых технологий отвечать на широкий круг вопросов студентов, без участия педагога. В статье излагаются результаты исследования и разработки подобных виртуальных помощников педагога. Одновременно указывается, что собранный материал диалогов бота со студентами позволяет использовать результаты для косвенного анализа успеваемости студента и формирования персональных образовательных траекторий.

Today the education is on the verge of the digital age as new learning approaches with advanced information and communication distant learning technologies, and academic process digitalization with neural networks and machine learning. The new digital learning environments and platforms help the teacher to develop and deliver digital learning content for high school and university students making it available globally over the Internet. However, the teacher efforts are multiplied, as more and more content is to be developed. Even more, an elearning teacher is expected to be available 24/7. Digital learning environments with a computerassisted assessment feature remove some of the burdens from the educator. Another option is using virtual teacher assistants or chatbots based on trained neural networks. they can answer a wide range of student questions without the teacher’s intervention. We studied the development of such virtual teacher assistants. The recorded student/chatbot scripts can be used to indirectly estimate the student’s academic performance, and to offer a customized learning path.
A Video Tracking System for the Registration of Upper Extremity Motions
Authors: Бурыкин Ю.Г.
Published: August 2021

Автором рассмотрены основные способы регистрации движений верхней конечности человека с помощью различных технических средств, описаны недостатки системы видеоанализа и предложены альтернативные варианты решения ряда задач, направленных на уменьшение потери информации при видеорегистрации. Регистрация пальцевого тремора и движений пальцев осуществлялась посредством видеокамеры на основе системы распознавания образов, путем идентификации 5 меток (маркеров), сгенерированных с помощью свободной библиотеки ArUco. В результате оптимизации параметров маркеров, а также настройки углов обзора и фокусного расстояния удалось снизить ошибки при распознавании образов и повысить надежность регистрации движений фаланг пальцев с помощью видеокамеры. Использование калибровочных фотографий, полученных с экрана монитора, расположенного в различных плоскостях, позволило повысить точность регистрации движений. Информация о параметрах двигательной активности человека актуальна для объективной оценки его психофизиологического состояния и координационных способностей, а также медицинской диагностики.

We considered the key methods for registering human upper extremity motions with various SW/HW tools, presented the drawbacks of video analysis systems, and proposed alternative solutions intended for reducing video information losses. We registered finger tremor/movement with a video camera and a pattern recognition system by identifying 5 markers generated with the AtUco open source library. By optimizing the marker properties, the view angles and the focal length we managed to reduce pattern recognition errors and improve phalanx movement video registration quality. Using reference photos taken from the monitor positioned at various angles also improved the motion registration quality. The human motion information is relevant to objectively assess the person’s psychophysiological status and physical coordination. It is also used for medical diagnostics.
Simulation of Dynamic Processes in Deformable Medium with the Grid-Characteristic Approach
Authors: Петров И.Б.
Published: August 2021

Существует значительное количество прикладных задач, для решения которых применяется математическое моделирование динамических процессов в деформируемых средах. К таким задачам относят моделирование распространения упругих волн в геологических средах, в том числе с учетом ледовых образований, их рассеяния на зонах трещиноватости. Актуальность этих постановок обусловлена важностью решения обратных задач сейсмической разведки, обработки данных сейсмической разведки с целью уточнения запасов углеводородов и определения расположения углеводородов и других полезных ископаемых. Поэтому приобретает важность разработка высокоточных численных методов, позволяющих моделировать упругие волны в деформируемых средах. Одним из этих методов является сеточно-характеристический численный метод, примененный в данной работе. Этот численный метод применяется для решения прямых задач, то есть для расчета распространения упругих волн при известных параметрах рассматриваемой среды. А для решения обратной задачи по восстановлению параметров геологической среды по данным сейсмической разведки можно применять нейронные сети, для обучения которых можно использовать многократное решение прямых задач сеточно-характеристическим методом. В данной работе приведены примеры решения разнообразных прямых задач по распространению упругих волн в неоднородных геологических средах, в том числе в зоне Арктики, а также представлена постановка задачи по обучению нейронных сетей и графики, показывающие эффективность их обучения с использованием двух различных подходов.

Many problems can be solved with the simulation of dynamic processes in deformable media. They are the simulation of elastic wave propagation in rocks including ice formations, and wave scattering on rock-fracture zones. Such studies are important for solving inverse problems of seismic exploration and seismic data processing to get a better estimation of hydrocarbon reserves, locate hydrocarbons and other minerals. Therefore, it is necessary to develop high-precision numerical methods used to simulate elastic waves in deformable media. One of such methods is the grid-characteristic approach used in this work. It is suitable for solving direct problems, i.e., to analyze the propagation of elastic waves in a medium with known properties. Neural networks can be applied to solve the inverse problem: reconstructing the geology from seismic survey data. Multiple solving of direct problems by the gridcharacteristic approach is used for network training. This paper contains some examples of solving a range of direct problems on the elastic wave propagation in heterogeneous rocks, also in the Arctic zone, and the problem statement for training neural networks and graphs is proposed to demonstrate the efficiency of training with two approaches.
Elastic Properties of Porous Media Containing Gas Hydrates
Authors: Губайдуллин А.А. , Болдырева О.Ю. , Дудко Д.Н.
Published: August 2021

Проведен анализ современного состояния экспериментальных и теоретических исследований упругих свойств гидратосодержащих пористых сред. Сделан вывод о том, что во всех экспериментах установлена связь скоростей упругих волн с содержанием гидрата в поровом пространстве, а именно, наблюдается рост скоростей с увеличением гидратонасыщенности. В области теоретических исследований созданы математические модели упругих модулей гидратосодержащих пористых сред, позволяющие качественно и количественно описать результаты лабораторных опытов.

The state-of-the-art experimental and theoretical studies of the elastic properties of porous media containing gas hydrate was analyzed. It is concluded that all the experiments identified a relationship between the elastic wave velocities and the hydrate content in the porous space: the velocities increase with higher hydrate saturation. The theoretical research produced simulation models for estimating the modulus of elasticity of hydrate-containing porous media to qualitatively and quantitatively describe the results of laboratory experiments.
Collaborative Development of Complex Software and Hardware Systems for High Data Rate Processing
Authors: Лаврентьев М.М. , Шадрин М.Ю. , Таранцев И.Г.
Published: August 2021

В работе рассматриваются вопросы построения простых и надежных решений для обработки непрерывных потоков данных на обычных операционных системах, которые не являются системами реального времени. Результаты получены в ходе плодотворного сотрудничества между Институтом автоматики и электрометрии СО РАН и ООО «СофтЛаб-НСК». Предлагаются необходимые и достаточные программно-аппаратные решения, объясняются принципиальные требования к функциональности программных и аппаратных компонент предлагаемых решений. Также в статье предлагается метод разделения программных компонент, обеспечивающий высокую надежность результирующей системы.

This study covers the development of simple and robust solutions for processing continuous data flows on conventional (not real-time) operating systems. It is collaborative research by the Institute of Automation and Electrometry and SoflLab-NSK. The necessary and sufficient software and hardware solutions are proposed, the basic requirements for the functionality of the software and hardware components of the proposed solutions are explained. This paper also proposes a software components separation method that ensures the high reliability of the resulting system.
Relative Importance of High-Latitude Local and Long-Range Transported Dust to Arctic Ice Nucleating Particles and Impacts on Arctic Mixed-Phase Clouds
Authors: Shi Yang , Liu Xiaohong , Wu Mingxuan , Ke Ziming , Brown Hunter
Published: August 2021

Abstract. Dust particles, serving as ice nucleating particles (INPs), may impact the Arctic surface energy budget and regional climate by modulating the mixed-phase cloud properties and lifetime. In addition to long-range transport from low latitude deserts, dust particles in the Arctic can originate from local sources. However, the importance of high latitude dust (HLD) as a source of Arctic INPs (compared to low latitude dust (LLD)) and its effects on Arctic mixed-phase clouds are overlooked. In this study, we evaluate the contribution to Arctic dust loading and INP population from HLD and six LLD source regions by implementing a source-tagging technique for dust aerosols in version 1 of the US Department of Energy’s Energy Exascale Earth System Model (E3SMv1). Our results show that HLD is responsible for 30.7 % of the total dust burden in the Arctic, whereas LLD from Asia and North Africa contribute 44.2 % and 24.2 %, respectively. Due to its limited vertical transport as a result of stable boundary layers, HLD contributes more in the lower troposphere, especially in boreal summer and autumn when the HLD emissions are stronger. LLD from North Africa and East Asia dominates the dust loading in the upper troposphere with peak contributions in boreal spring and winter. The modeled INP concentrations show a better agreement with both ground and aircraft INP measurements in the Arctic when including HLD INPs. The HLD INPs are found to induce a net cooling effect (−0.24 W m−2 above 60° N) on the Arctic surface downwelling radiative flux by changing the cloud phase of the Arctic mixed-phase clouds. The magnitude of this cooling is larger than those induced by North African and East Asian dust (0.08 and −0.06 W m−2, respectively), mainly due to different seasonalities of HLD and LLD. Uncertainties of this study are discussed, which highlights the importance of further constraining the HLD emissions.
Swiss halocarbon emissions for 2019 to 2020 assessed from regional atmospheric observations
Authors: Rust Dominique , Katharopoulos Ioannis , Vollmer Martin K. , Henne Stephan , O'Doherty Simon , Say Daniel , Emmenegger Lukas , Zenobi Renato , Reimann Stefan
Published: August 2021

Abstract. Halocarbons are emitted by various anthropogenic activities to the atmosphere, where they contribute to global warming and stratospheric ozone-depletion. To determine national halocarbon emissions, the so-called "top-down" approach relies on atmospheric observations, at sites that reflect emissions on a country level, and com-bines these observations with inverse modelling methods. In this study, we present 12 months (September 2019 to September 2020) of continuous atmospheric observations of 28 halocarbons from a measurement campaign at the Beromünster tall tower in Switzerland. The site is sensitive to the most densely populated area of Switzer-land, the Swiss Plateau, thus the measurements were well suited to derive Swiss halocarbon emissions. Emissions were calculated by two different top-down methods, a tracer-ratio method (TRM) with carbon monoxide (CO) as the independent tracer, and a Bayesian inversion (BI), based on atmospheric transport simulations using FLEXPART–COSMO. The results were compared to previously reported top-down emission estimates, based on measurements at the high-Alpine site Jungfraujoch, and to the "bottom-up" Swiss national greenhouse gas (GHG) inventory, as annually reported to the United Nations Framework Convention on Climate Change (UN-FCCC). We observed ongoing outgassing from existing foams and refrigerators for the ozone-depleting, banned chlorofluorocarbons (CFCs) and the regulated hydrochlorofluorocarbons (HCFCs), confirming their large historical use. For the major hydrofluorocarbons (HFCs) HFC-125 (CHF2CF3) and HFC-32 (CH2F2), our calcu-lated emissions of 99 ± 29 Mg yr−1 and 46 ± 13 Mg yr−1 were in good agreement with the national Swiss inventory values, whereas for HFC 134a (CH2FCF3) our result of 300 ± 85 Mg yr−1 was about 30 % lower than the UNFCCC reported value. For the other investigated HFCs, perfluorocarbons (PFCs), SF6 and NF3, emissions were small and in agreement with the inventory. Finally, we report the first country-based emission estimates of a total of 50 Mg yr−1 for three recently phased-in, unregulated hydrofluoroolefins (HFOs), HFO 1234yf (CF3CF=CH2), HFO-1234ze(E) ((E)-CF3CH=CHF) and HCFO-1233zd(E) ((E) CF3CH=CHCl).
Influence of the representation of convection on the mid-Holocene West African Monsoon
Authors: Jungandreas Leonore , Hohenegger Cathy , Claussen Martin
Published: August 2021

Abstract. Global climate models experience difficulties in simulating the northward extension of the monsoonal precipitation over north Africa during the mid-Holocene as
revealed by proxy data. A common feature of these models is that they usually
operate on grids that are too coarse to explicitly resolve convection, but convection
is the most essential mechanism leading to precipitation in the West African
Monsoon region. Here, we investigate how the representation of tropical deep
convection in the ICOsahedral Nonhydrostatic (ICON) climate model affects the meridional distribution of
monsoonal precipitation during the mid-Holocene by comparing regional
simulations of the summer monsoon season (July to September; JAS) with
parameterized and explicitly resolved convection. In the explicitly resolved convection simulation, the more localized nature of precipitation
and the absence of permanent light precipitation as compared to the
parameterized convection simulation is closer to expectations. However, in the JAS mean,
the parameterized convection simulation produces more precipitation and extends further
north than the explicitly resolved convection simulation, especially between 12 and
17∘ N. The higher precipitation rates in the parameterized convection
simulation are consistent with a stronger monsoonal circulation over
land. Furthermore, the atmosphere in the parameterized convection simulation is less
stably stratified and notably moister. The differences in atmospheric water
vapor are the result of substantial differences in the probability
distribution function of precipitation and its resulting interactions with the
land surface. The parametrization of convection produces light and large-scale
precipitation, keeping the soils moist and supporting the development of
convection. In contrast, less frequent but locally intense precipitation
events lead to high amounts of runoff in the explicitly resolved convection
simulations. The stronger runoff inhibits the moistening of the soil during
the monsoon season and limits the amount of water available to evaporation in
the explicitly resolved convection simulation.
The blue suns of 1831: was the eruption of Ferdinandea, near Sicily, one of the largest volcanic climate forcing events of the nineteenth century?
Authors: Garrison Christopher , Kilburn Christopher , Smart David , Edwards Stephen
Published: August 2021

Abstract. One of the largest climate forcing eruptions of the nineteenth century was, until recently, believed to have taken place at Babuyan Claro volcano, in the Philippines, in 1831. However, a recent investigation found no reliable evidence of such an eruption, suggesting that the 1831 eruption must have taken place elsewhere. A newly compiled dataset of reported observations of a blue, purple and green sun in August 1831 is here used to reconstruct the transport of a stratospheric aerosol plume from that eruption. The source of the aerosol plume is identified as the eruption of Ferdinandea, which took place about 50 km off the south-west coast of Sicily (lat. 37.1° N., long. 12.7° E.), in July and August 1831. The modest magnitude of this eruption, assigned a Volcanic Explosivity Index (VEI) of 3, has commonly caused it to be discounted or overlooked when identifying the likely source of the stratospheric sulphate aerosol in 1831. It is proposed, however, that convective instability in the troposphere contributed to aerosol reaching the stratosphere and that the aerosol load was enhanced by addition of a sedimentary sulphur component to the volcanic plume. One of the largest climate forcing volcanic eruptions of the nineteenth century would thus effectively have been hiding in plain sight, arguably ‘lowering the bar’ for the types of eruptions capable of having a substantial climate forcing impact. Prior estimates of the mass of stratospheric sulphate aerosol responsible for the 1831 Greenland ice-core sulphate deposition peaks which have assumed a source eruption at a low-latitude site will therefore have been overstated. The example presented in this paper serves as a useful reminder that VEI values were not intended to be reliably correlated with eruption sulphur yields unless supplemented with compositional analyses. It also underlines that eye-witness accounts of historical geophysical events should not be neglected as a source of valuable scientific data.
The Geophysical Observatory in Sodankylä, Finland – past and present
Authors: Bösinger Tilmann
Published: August 2021

Abstract. After a preface, we will first try to depict the history of the Geophysical
Observatory in Sodankylä (SGO) by referring to the personalities who have run and have shaped the observatory. Thereafter, we describe the history from a technical point of view, i.e., what the measurements were, and which instruments were primarily used at the observatory. We will also refer to present operational forms and techniques. We start with the very first systematic meteorological and geophysical
observations made in Finland and end by referring to the involvement in
ongoing international scientific programs.
Kişilik Özellikleri ve Sosyo-demografik Faktörler ile Yöneticilerde İş Doyumu ve İş Performansının Yordanması
Authors: TATAR Arkun , ÇELİKBAŞ Behmen
Published: August 2021

Bu çalışmada yönetici konumunda çalışan kişilerin, kişilik özelliklerinin iş performansı ve iş doyumu üzerindeki etkisinin incelenmesi amaçlanmıştır. Çalışma beklentisi iş performansı ve iş doyumu gruplarının yordanmasında farklı kişilik ölçümlerinin olacağıdır. Belirlenecek farklı kişilik özelliklerinin ise psikolojik ve örgütsel işleyiş açısından farklılık göstereceği düşünülmektedir. Çalışmaya, en az 10 astı bulunan ve en az üç yıl süreyle bir kuruluşta çalışan 269 yönetici alınmıştır. İş performansı ve iş doyumu gruplarının yordanması çok değişkenli lojistik regresyon analiziyle yapılmıştır. İş performansı gruplarının yordanması için kurulan iki modelde Canlılık, Kendine Güvensizlik, Duyarlılık, Dışadönüklük, cinsiyet ve gelir durumu yer almıştır. İş doyumu gruplarının yordanması için kurulan iki modelde ise Canlılık, Kendine Güvensizlik, Duyarlılık, Hoşgörü, cinsiyet ve gelir durumu yer almıştır. Her ikinin olgunun da büyük oranda aynı kişilik özellikleri tarafından yordandığı görülmüştür. Elde edilen sonuçlar ilgili literatür doğrultusunda tartışılmıştır.
Relationship between Religiosity and Life Satisfaction in Undergraduate Students at Kohat University of Science & Technology KPK Pakistan
Authors: Zahoor Nayab , Khattak Alam Zeb , Amjad Muhammad , Shaukat Sukaina , Khanum Uzma , Raziq Urooj
Published: August 2021

The present study was conducted to investigate the relationship between closeness to religion and satisfaction in life in undergraduate students at Kohat University of Science & Technology (KUST), KPK, Pakistan. A total sample of 100 undergraduate students was selected through a convenience sampling technique comprising 50 male and 50 female undergraduate students. The questionnaires were uploaded as Google forms to collect data virtually from the participants due to the current COVID-19 pandemic in Pakistan. The undergraduate students having age range 20-22 years were included in the study. Two different standardized tools, Satisfaction with Life Scale developed by Diener et al. (1985) and Daily Spiritual Experience Scale developed by Underwood and Teresi (2002) were used. The data was analyzed by mean, standard deviation, and Pearson’s product-moment correlation. The results showed significant positive correlations between religiosity, religious well-being, and life satisfaction. It is suggested for researchers to explore more variables related to religiosity and life satisfaction.
Pedagogia do oprimido, de Paulo Freire: suscitando diálogos e reflexões a partir de experiências em/com Educação
Authors: Busquet Líbia da Silva Soares , Oliveira Carlos César de , Oliveira Elaine Ferreira Rezende de , Morais Jacqueline de Fatima dos Santos
Published: August 2021

ste artigo, construído a partir do encontro dos autores com a obra Pedagogia do oprimido, de Paulo Freire, configura três momentos: o vínculo da obra com o contexto da Educação Popular, com base em Streck e Esteban (2013), Streck (2009) e Carrillo (2013); a interface com o Teatro do oprimido, alicerçado em Boal (1991, 2009); e, por fim, a inspiração freiriana em práticas de alfabetização com crianças, conforme a Secretaria de Educação do Ceará (198-). Fundamentado em Bourdieu (2006), trata-se de um estudo que tem como referência as trajetórias sociais dos pesquisadores que, mediante diálogos e reflexões suscitados pela obra, expressam seus percursos pessoais, profissionais e suas práticas docentes. Constituído a partir de uma revisão de literatura, o estudo espera tecer alguns diálogos e contribuir com a produção e as pesquisas inspiradas na obra de Paulo Freire e na sua Pedagogia do oprimido, com vistas a fornecer uma fonte de atualização para os leitores.
Economic Strategy in Kuwait and Currency Stability Factors
Authors:   MSc Development Economics, Department of Economics, SOAS University of London, United Kingdom, Almutairi Mariam
Published: August 2021

Recently there has been an increase in interest in using a strategy for developing a strategy on which the economy is based in countries, and it has become one of the most important indicators of the development of society, and development in society is not achieved without its presence, as the world is going through our time with economic problems and crises that did not exist before. It was affordable in front of developing and backward societies that did not develop a deliberate economic strategy, but it was better with countries that are aware of this development and the importance of planning to achieve economic development in the country. Therefore, the study aimed to try to identify the economic strategy followed in the State of Kuwait, and what are the factors affecting the exchange rate and how The stability of the currency in the country, and the plans developed by the State of Kuwait by studying economic indicators and benefiting from previous studies of economic planning. The descriptive approach was used to determine the weariness of the strategy followed to raise the economic development in the country.
“fusión de horizontes” de Gadamer para la historia de las mujeres y de género con base en la noción de la historia de John Gaddis
Authors: Neves Camila
Published: August 2021

Este artículo aborda la “fusión de horizontes” de Hans-Georg Gadamer, en complemento con la noción de la historia de John Gaddis, vista desde su proyección sobre la historia de las mujeres y de género. La conjunción entre las nociones de Gaddis y Gadamer permite comprender la cercanía entre el historiador y el pasado, lo cual contribuye al carácter ético-político de la historia. Con base en la comparación entre dichas nociones, se infiere que la historia de las mujeres y de género, a través del carácter simétrico del encuentro entre dos horizontes, libera al pretérito y, en virtud de ello, otorga voz al movimiento feminista a partir de la transmisión de las experiencias de mujeres al inacabado debate político sobre problemáticas de mujeres y género.
THE FEDERAL RESERVE’S MONETARY POLICY AND ITS EFFECTS (2008-2020): AN AUSTRIAN PERSPECTIVE
Authors: Marques André
Published: August 2021

Este paper tem como objetivo descrever, segundo a Escola Austríaca de Economia, como as políticas monetárias adotadas pelo Federal Reserve a partir de 2008 (Quantitative Easing – QE, Qualitative Easing – QL e Zero Percent Interest Rate Policy – ZIRP) prolongaram os desajustes na alocação de recursos, enfraqueceram a economia americana (indivíduos e empresas tornaram-se mais dependentes de juros artificialmente baixos) e aumentaram os riscos e a alavancagem presentes no mercado financeiro. Argumenta-se que, após a adoção destas políticas, o Fed não seria capaz de normalizar a política monetária, o que se confirmou em 2019, quando Fed voltou a diminuir o FFR e a realizar QE, e, sobretudo, em 2020, quando retornou ao ZIRP e aumentou o QE. Conclui-se, portanto, que o Fed enfraquece a economia e aumenta a alavancagem do mercado financeiro. A economia real é prejudicada em detrimento do mercado financeiro (grandes empresas de capital aberto e instituições financeiras) e do governo (que aumenta seus gastos e endividamento).
Palavras-Chave: Escola Austríaca de Economia, Estados Unidos, Bancos Centrais, Federal Reserve, Política Monetária, Ciclos Económicos.
Classificação JEL: E14, E32, E43, E44, E52, E58, E62, H60.
Setting up the braking force measurement system of the tractor semi-trailer
Authors: Tung Nguyen Thanh
Published: August 2021

The braking force of the tractor semi-trailer depends on many random factors and road parameters. Therefore, determining the braking force based on theoretical calculation or simulation is not accurate. This paper presents the method of setting up the braking force measurement system of the tractor semi-trailer on the road and constructing the braking dynamics model of the tractor semi-trailer to investigate the braking force using Matlab-Simulink software. The study results show that the average error between the simulation and experimental results of the tractor semi-trailer braking force is 9,81%.
Development and implementation of an algorithm for preventive machine maintenance
Authors: Nardo Mario Di , Converso Giuseppe , Castagna Francesco , Murino Teresa
Published: August 2021

This paper aims to develop a maintenance optimization model to maintain a high level of efficiency and reliability of the machinery. The methodological approach is based on preventive maintenance through the partial or total replacement of critical components. Although an intermediate intervention control, the focus is on a particular machine that has stopped several times, reducing its operational availability and resulting in a high cost of non-production. This study uses a Weibull model to analyze and optimize the correct maintenance process of the machinery considered. The failure data are then analyzed and scheduled. The final purpose is to standardize the operators' intervention procedures to reduce the time for the same interventions.
DEMOGRAPHIC CHARACTERISTICS OF THE SEROPREVALENCE OF HUMAN TOXOCARIASIS AMONG THE POPULATION OF NORTH-EASTERN BULGARIA
Authors:   Department of Infectious Diseases, Parasitology and Dermatovenereology, Faculty of Medicine, Medical University - Varna, Bulgaria., Cvetkova Tatyana , Stoyanova Kalina ,   Department of Infectious Diseases, Parasitology and Dermatovenereology, Faculty of Medicine, Medical University - Varna, Bulgaria., Paunov Tsonko ,   Department of Hygiene and Epidemiology, Faculty of Public Health, Medical University - Varna, Bulgaria., Pavlov Stoyan ,   Department of Anatomy and Cell Biology, Faculty of Medicine, Medical University - Varna, Bulgaria.
Published: August 2021

Toxocariasis is a tissue zoonosis caused by Toxocara spp. and the exposure to these geohelminths varies in different parts of the population in a particular region. The purpose of the study is to reveal the seroprevalence of toxocariasis in North-eastern Bulgaria and to establish its demographic structure. Material/Methods: Within the scope of a broad seroepidemiological study, 701 individuals from North-eastern Bulgaria were tested for anti-Toxocara antibodies (ELISA) between 2017 and 2020. The results were stratified and analysed by age, gender, and place of residence. Results: The overall seroprevalence of human toxocariasis in North-eastern Bulgaria is 18.54%. Children (18.85%) and adults (18.30%) show similar levels of infection, but the stratified analysis by age in 5-years intervals revealed notable discrepancies. In younger children, the seroprevalence is higher than the observed for the entire population (0-4 years - 22.22%; 5-9 years - 22.22%), while in adolescents and adults is lower than average. In the elderly, the seroprevalence rises to its highest levels (60-64 years - 30.56% and over 65 years -31.67%). Although there are variations between males and females, gender is not a significant factor for the distribution of toxocariasis. Higher seroprevalence levels in residents of the smaller settlements of the region (children - 28.18%; adults -29.10%) correspond to a 2.5-fold increase in the odds of contracting toxocariasis in comparison to the ones living in Varna city. Conclusion: The overall seroprevalence of toxocariasis in North-eastern Bulgaria is alarmingly higher than the levels reported from other parts of the country, placing this unknown infection in a leading position among the parasitic zoonoses. The place of residence is the most significant factor driving the uneven distribution of the disease.
STUDYING THE OPINION OF THE POPULATION ON THE ORGANIZATION AND QUALITY OF DENTAL CARE
Authors: Алиакбар Е. , Бейсбекова А.К. , Нурбакыт А.Н. , Маханбеткулова Д.Н.
Published: August 2021

В условиях социального медицинского страхования удовлетворенность пациентов полученной медицинской помощью является одним из основных критериев оценки её качества. Цель исследования. Оценить уровень удовлетворенности пациентов, получающих лечение в стоматологическом кабинете. Материал и методы. Был проведен социологический опрос 83 пациентов, получающих лечение в стоматологическом кабинете. Выводы. На основании проведенного нами опроса и полученных результатов выявлено, что в целом респонденты отмечают удовлетворенность стоматологической услугой. Также отмечают высокое качество оказываемых услуг.

In the context of social health insurance, the satisfaction of patients with the received medical care is one of the main criteria for assessing its quality. Purpose of the study. Assess the level of satisfaction of patients receiving treatment in the dental office. Material and methods. A sociological survey was conducted of 83 patients receiving treatment in the dental office. Conclusions. Based on our survey and the results obtained, it was revealed that, in general, the respondents note satisfaction with the dental service. They also note the high quality of the services provided.
MODERN MEDICAL AND SOCIAL ASPECTS OF MORBIDITY AND MORTALITY RATES IN THE WORKING AGE POPULATION
Authors: Булешов М.А. , Алипбекова С.Н. , Туктибаева С.А.
Published: August 2021

В статье проведен анализ проблем современных аспектов показателей здоровья населения трудоспособного возраста, в частности показателей заболеваемости и смертности, путем обзора отечественной и зарубежной литературы

The article analyzes the problems of modern aspects of health indicators of the working-age population, in particular, indicators of morbidity and mortality, by reviewing domestic and foreign literature.
EFFECT OF AMBIENT TEMPERATURE ON MORTALITY IN ACUTELY ILL HOSPITALIZED OLDER PATIENTS
Authors: Garcez Flávia Barreto , Jacob-Filho Wilson , Avelino-Silva Thiago Junqueira
Published: August 2021

OBJECTIVE: To investigate the association between extremes of temperature and increased hospital mortality in acutely ill older patients. METHODS: A prospective cohort study of acutely ill patients aged 60 years or older, admitted to the geriatric ward of Hospital das Clinicas at the University of Sao Paulo Medical School, from 2009 to 2015. Meteorological data were obtained through the System of Information on Air Quality of the state of Sao Paulo. The average daily temperatures were categorized according to percentiles (p). Temperatures at p95 and p90 were defined as extreme heat and those below p10 and p5 as extreme cold. We collected sociodemographic, clinical, functional, and laboratory data on admission using a standardized comprehensive geriatric assessment. The primary outcome was hospital mortality. We performed multivariate analyses using Cox proportional hazards model adjusted for confounders. RESULTS: We included 1403 patients, with a mean age of 80 years; 61% were women. The overall mortality was 19%. Temperature cutoffs by percentile were 15, 16, 25, and 26°C. The adjusted hazard ratio for all-cause mortality in the ≥ 26°C temperature group compared to the 16.1–25.0°C group was 1.89 (27 vs 18%; 95%CI 1.14–3.12; p = 0.013). There was no significant association between the other temperature groups and mortality. CONCLUSIONS: A daily temperature > 26°C was independently associated with increased hospital mortality. Health administrators and clinicians should be aware of the potential negative effects of high ambient temperatures on hospitalized older patients.
FRAILTY AND MORTALITY RISK IN PATIENTS WITH SEVERE COVID-19: PROGNOSIS BEYOND THE AGE CRITERION
Authors: Aliberti Márlon Juliano Romero , Szlejf Claudia , Suemoto Claudia Kimie , Dias Murilo Bacchini , Jacob-Filho Wilson , Avelino-Silva Thiago Junqueira
Published: August 2021

OBJECTIVE: To investigate the association between frailty and death in hospitalized patients with COVID-19. METHODOLOGY: Prospective cohort study with patients ≥ 50 years hospitalized with COVID-19. Frailty was assessed using the Clinical Frailty Scale and the frailty index. Patients with a Clinical Frailty Scale score ≥ 5 were considered frail. The primary endpoints were mortality at 30 and 100 days after hospital admission. We used Cox proportional hazard models to investigate the association between frailty and mortality. We also explored whether frailty predicted different mortality levels among patients within strata of similar age and acute disease severity (Sequential Organ Failure Assessment score). RESULTS: A total of 1,830 patients were included (mean age 66 years; 58% men; 27% frail according to Clinical Frailty Scale score). The mortality risk at 30 days (adjusted hazard ratio = 1.7; 95% CI 1.4 - 2.1; p <0.001) and 100 days (adjusted hazard ratio = 1.7; 95% CI 1.4 - 2.1; p <0.001) was almost double for frail patients. The Clinical Frailty Scale also predicted different mortality levels among patients within strata of similar age and acute disease severity. Frailty intensified the effect of acute disease severity on the risk of death (p for interaction = 0.01). Of note, the Clinical Frailty Scale achieved outstanding accuracy to identify frailty according to the frailty index (area under the ROC curve = 0.94; 95% CI 0.93 - 0.95). CONCLUSIONS: Our results encourage the use of the Clinical Frailty Scale in association with measures of acute disease severity to determine prognosis and promote adequate resource allocation in hospitalized patients with COVID-19.
Inefficient Mapping
Authors: Knight Linda
Published: August 2021

Working from a speculative, more-than-human ontological position, Inefficient Mapping: A Protocol for Attuning to Phenomena presents a new, experimental cartographic practice and non-representational methodological protocol that attunes to the subaltern genealogies of sites and places, proposing a wayfaring practice for traversing the land founded on an ethics of care. As a methodological protocol, inefficient mapping inscribes the histories and politics of a place by gesturally marking affective and relational imprints of colonisation, industrialisation, appropriation, histories, futures, exclusions, privileges, neglect, survival, and persistence.

Inefficient Mapping details a research experiment and is designed to be taken out on mapping expeditions to be referred to, consulted with, and experimented with by those who are familiar or new to mapping. The inefficient mapping protocol described in this book is informed by feminist speculative and immanent theories, including posthuman theories, critical-cultural theories, Indigenous and critical place inquiry, as well as the works of Karen Barad, Erin Manning, Jane Bennett, Maria Puig de la Bellacassa, Elizabeth Povinelli, and Eve Tuck and Marcia McKenzie, which frame how inefficient mapping attunes to the matter, tenses, and ontologies of phenomena and how the interweaving agglomerations of theory, critique, and practice can remain embedded in experimental methodologies.
The Perception towards Ketogenic Diet among General Population in Rawalpindi
Authors: . Ubaidullah , Tahir Huma , Khan Zarak , Tahir Muhammad
Published: August 2021

Objective: The aim of study is to determine the knowledge and perception towards ketogenic diet among general population, as a weight lowering technique for a shorter period of time. Study Design: Cross sectional study Place and Duration: The study was conducted on general public of Rawalpindi and the duration of study was of six months i.e from 15thJan 2020 to 14thJuly 2020. Methods: Data was collected through questionnaires and each question measured with the help of five Likert Scale (Strongly disagree, Disagree, Neutral, Agree, strongly agree). More than 10 questions were asked from the general public in Rawalpindi of all age groups and analyzed through Microsoft Excel. The questionnaire was distributed via internet-based google form. The respondents actively and willingly participated in the survey. Keeping in mind the current pandemic situation, it was difficult to reach out the people in person, so we used simple convenient sampling technique. Some of the data was collected by using snowball sampling technique.The respondents from Rawalpindi region were included in the study whereas all from other cities were excluded. Results: There were68 (81%) females and 16 (19%) males in this study. Most of the patients 36 (42.9%) were from <25 years of age, 29 (34.5%) patients were between age group 26-35, 18 (21.4%) were between 36-45 years of age and the rest were >46 years of age. Findings show that ketogenic diet is the most popular weight losing technique these days. While 47% of the people believe that the diet shall be followed under the supervision of a physician keeping in mind the risks associated with it. Conclusion: Ketogenic diet is a popular weight loss diet these days. The general population somehow have the knowledge about the pros and cons of the diet. But still there is a dire need of health promotion and education regarding intake of ketogenic diet. The results are insignificant due to limited time and pandemic situation, so we are unable to gather significant amount of sample to know the actual reason behind younger population’s inclination towards ketogenic diet. Key Words: Keto-diet, Ketogenic, Perception and Knowledge
Should judges be neutral?
Authors: Hogan Gerard
Published: August 2021

This is a slightly revised version of the MacDermott Lecture delivered (virtually) at Queen’s University, Belfast, on 27 May 2021.
PROSPECTS FOR THE USE OF JUNGAR MULLEIN (VERBASCUM SONGARICUM SCHRENK) AS A MEDICINAL RAW MATERIAL
Authors: Гафурова К.Г. , Кожанова К.К. , Махатова Б.Г. , Момбеков С.Е.
Published: August 2021

В этой статье представлена общая информация о химических и лечебных свойствах коровяка джунгарского (Verbascum songaricum Schrenk). Написано о перспективности и актуальности изучения коровяка джунгарского (Verbascum songaricum Schrenk) как лекарственного растительного сырья

This article provides general information on the chemical and medicinal properties of the Djungarian mullein (Verbascum songaricum Schrenk). It is written about the prospects and relevance of the study of the Djungarian mullein (Verbascum songaricum Schrenk) as a medicinal plant material
THEORETICAL FOUNDATIONS OF STUDENTS ADAPTATION TO LEARNING LOADS BY MEANS OF HYPOXIC TRAINING
Authors: НУРГАЛИЕВА А. , ЕРЛАН А.Е. , БАБАШЕВ А.М. , АСАН Г.
Published: August 2021

В данной статье указан литературный обзор о перспективном влиянии интервальной гипобарической гипоксии с нормоксии на учащихся высших учебных заведений. После длительного влияние сеансов наблюдалось корректировка их функционального состояние, повышение неспецифической резистентности к стрессу, снижения уровня холестерина, улучшение состояние сердечно-сосудистой системы.

This article provides a literary review of the promising effect of interval hypobaric hypoxia with normoxia on students of higher educational institutions. After a longterm effect of the sessions, there was an adjustment in their functional state, an increase in nonspecific resistance to stress, a decrease in cholesterol levels, and an improvement in the state of the cardiovascular system.