bluuebunny/crossref_metadata_2025 huggingface dataset:
Demographic Factors and Co Morbidities Associated with Post Covid-19 Recovery among Admitted Patients in Tertiary Care Hospitals of Khyber Pakhtunkhwa
Authors: Mabood Jawad , Khan Hamza , Uzair Syed , Ahmad Israr , Nouman Muhammad , Ullah Haider Ehsan , Shahi Alishba , Burki Gulalai
Published: January 2023

Objective: To study the relationship of demographic factors and co-morbidities with post-COVID-19 recovery in tertiary care hospitals of Peshawar. Methodology: This research was conducted in tertiary care hospitals of Khyber Pakhtunkhwa extending over a period of 6 months starting from 1st July 2020 to 31st December 2020. It was an analytical descriptive study (cross-sectional). Patients were selected through a non-probability consecutive sampling technique. Descriptive statistics were performed with SPSS software 22.0 in the form of the mean (sd) and percentages while univariate and multivariate logistic regression scrutiny was performed with STATA version 13.0. Results: A mean age (48.94±17.57) was observed up to the post-infection recovery or death. The mean age of post-infection recovered patients in the age series of 18-35 years and >55 years was significantly significant (P<0.05) Out of those who recovered, 110 (79.5%) were males and 49(20.5%) were females while those who died of the infection 15(36.6%) were females and 26(83.8%) were males. Univariate analysis showed that age, residence, hypertension, and ischemic heart disease were the covariates significantly associated (p.value <0.05) with post COVID recovery. In multivariate analysis with adjusted OR, “residence” was the only covariate associated with post-infection recovery. Adjusting for the effect of age, gender, hypertension, diabetes, ischemic heart disease, those who were living in urban areas were most likely to recover from COVID-19 infection as compared to the peri-urban residents (OR=0.067, CI: 0.013-0.333). In the full deduced model, adjusting for age, gender, diabetes, hypertension and ischemic heart disease, being an urban resident was 0.08 times more likely to survive or alive after getting COVID-19 infection as compared to dwellers living in city outskirts (OR=0.08, CI: 0.016-0.360). Conclusion Patients suffering from chronic hypertension and ischemic heart diseases were the most affected having higher post-infection mortalities compared to diabetic patients while, from a demographic point of view, being a resident of an urban area was a protective factor for post-infection recovery. Keywords: Demographic factors, co-morbidities, hypertension, ischemic heart disease, diabetes mellitus.
Risk Factors Involved in Recurrence of Pterygium Excision after Surgical Excision
Authors: Waseem Muhammad , Bhatti Shahid Anwar , Khan Muhammad Ayub , Babar Zaheer Uddin , Rafe Abdul , Saleem Haroon
Published: January 2023

Aim: To determine the effect of the type and size of growth, sex and patients age, and the application of mitomycin-C intraoperatively and its application duration effect on pterygium recurrence afterwards excision. Study Design: A retrospective and descriptive case series. Place and Duration: In Alshifa Trust Eye Hospital, Rawalpindi and the department of Ophthalmology CMH, Lahore for the duration from November 2022 to April 2022. Methods: Data files from 80 patients (80 eyes) who underwent bare sclera technique surgery with MMC at 0.2 mg / ml (0.02%) and application time ranging from 1 to 5 mints. The study included 60 males and 20 females with 46.4 years of mean age (16 to 60 years). Cases were classified according to sex, age, pterygium type and size and MMC application time. The main outcome measures were to compare the eye affected by the pterygium for any type of recurrence after at least 1-year of follow-up. Results: In our case series, the rate of pterygium recurrence was 10% in the mean follow-up of 1 year. The influencing factors like younger age at admission (<50 years), secondary pterygium (p = 0.330) was suggestively related with pterygium recurrence. There was a clear tendency of less rate of recurrence with smaller pterygium size, with MMC administration times greater than 3 minutes. However, it was not possible to obtain statistical significance due to the smaller sample size. Conclusions: This study results propose that younger age < 50-years, a history of multiple recurrences, increased size and a duration of MMC administration < 3 mints are risk factors for postoperative recurrence of pterygium
Association of Serum Leptin with Gestational Diabetes Mellitus
Authors: Memon Shaima Sultana , Ali Fizzah , , Haque Soha , Saad Saadia , Iqbal Zafar , Iftikhar Uzma
Published: January 2023

Background: It has been stated that leptin has a role in glucose regulation as it decreases the insulin resistance and regulates the insulin mediated glucose metabolism. As the body need more glucose, more secretion of insulin which stimulates adipose tissues to secrete more leptin which causes the release of cytokines which decreases insulin sensitivity and develop insulin resistance. The aim of the current study was to find out the association of serum leptin with gestational diabetes mellitus in current setting. Methods: A case control study was conducted at the Gynecology department of Abbasi Shaheed Hospital Karachi during April to September 2022. A self-designed proforma was used, consisting of 4 parts consisting of demographic variables, general physical examination and laboratory findings. Blood sample was collected during 24th to 28th week of gestation for testing fasting blood sugar, OGTT and then ELISA was done. Statistical Package for Social Science (SPSS) version-20 was used to analyze the data. p-value ≤0.05 was considered as significant. Results: The mean age of the study participants was 27.42 ± 0.39 and 24.96 ± 0.51 in cases and controls respectively. The basal metabolic index (BMI) was higher among the cases of gestational diabetes as compared to normal controls. Likewise, oral glucose tolerance test results showed higher levels of blood glucose than the normal controls during all steps of the test. The comparison of serum insulin and serum leptin during pregnancy and after delivery in cases of gestational diabetes showed a decrease in both serum insulin and serum leptin levels with significant p-value (p-value ≤0.05). Conclusion: Leptin is the contributory factor of insulin resistance and leads to gestational diabetes mellitus. Both serum insulin and serum leptin levels were having strong significant association with gestational diabetes mellitus. Keywords: Gestational diabetes mellitus, Serum Leptin, Hyperinsulinemia
Spontaneous Expulsion of Lower Ureteric Stones in Patients with Elevated Level of C-Reactive Protein
Authors: Hamid Haris , Ali Israr , Ullah Rafi , Ghani Akhtar , Klazir Zubaida Khanum , Ullah Sibghat , Khan Muhammad Ijaz
Published: January 2023

Background: Around 4–15% of people worldwide have urolithiasis, and ureteric stones account for around 20% of this condition. One of the most frequent situations a urologist has to deal with is acute renal colic caused by urolithiasis. Objective: To determine the spontaneous expulsion of lower ureteric stones in patients with elevated level of c-reactive protein Methodology: This descriptive cross sectional study was performed at the urology department Khalifa Gul Nawaz Teaching Hospital, Bannu Medical College Bannu for a period of six months from January 2022 to June 2022. A total of 210 patients were included in the study using non probability consecutive sampling. All patients had lower ureteric stone and raised CRP. Patients were followed till spontaneous expulsion or stone clearance. Data was analyzed using IBM SPSS version 23. Results: A total of 210 patients were enrolled in this study. There were 112(53.33%) were female and 98(46.67%) were male. Patients included in the study had age range from 18- 60yr,mean age was 34.32±7.92 SD. Patients selected in the study had lower ureteric stones ranging from 5-9mm. mean stone size was 6.990 mm ±0.92 SD. Mean CRP was 3.36 mg/dl ±1.99 SD. 50 (31.25%) patients with CRP 0.5-4.9mg/dl passed stones spontaneously while 45 (90%) patients with CRP 5-9.9 mg/dl passed stone spontaneously. Conclusion: Serum CRP is a relatively newer marker now increasingly being used for the purpose of predicting spontaneous stone expulsion of small lower ureteric stones. However current evidence still does not support CRP levels alone to be recommended for this purpose. Clinical assessment of every individual patient is still the mainstay of decision for intervention. Keywords: Spontaneous expulsion; lower ureteric stones; c-reactive protein
Frequency of Neutropenia in HIV Patients in Tertiary Care Hospital
Authors: Syed Saliha , Khan Shahtaj , Rehman Ansa Kulsoom , Iftikhar Sundas , Bhadur Laila , Arooj Hira
Published: January 2023

Introduction: HIV is the systemic illness known as acquired immune deficiency syndrome (AIDS). According to the report of World Health Organization, 33.2 million people has infected by Human Immunodeficiency Virus. Objective: To determine the frequency of neutropenia in HIV patients in tertiary care hospital. Material and method: The current study was Descriptive, cross sectional study. It was carried out in Hematology department, Hayatabad Medical Complex, Peshawa from 30/10/2018 to 30/4/2019. The demographic and clinical data of all patients including age, gender, occupation, residence, neutrophil count and HIV status were recorded on predesigned proforma. The study data was analyzed using SPSS version 17. Results: In our study, totally 114 patients were included. There were 71(62%) male patients and 43(38%) female patients in our study. Based on neutropenia status 17(15%) patients were observed with neutropenia whereas 97(85%) patients were not observed with neutropenia Conclusion: Our study concludes that the frequency of neutropenia was 15% in HIV patients in tertiary care hospital. Keywords: neutropenia, HIV, AIDS, Prevalence
Frequency of Insulin Resistance and Their Association with BMI in Polycyclic Ovarian Syndrome
Authors: Obaid Seher , Khan Shair Zaman , Kakar Iftikhar Ali , Kakakhel Susan
Published: January 2023

Background: Polycystic Ovary Syndrome (PCOS) is among the most prevalent endocrine conditions that affects women of reproductive age. Genetics, obesity, birth weight and insulin resistance are some of the inherited and environmental variables that have been associated to the etiology of PCOS. Objective: To study the frequency of insulin resistance and their association with BMI in polycyclic ovarian syndrome Methods: This study was cross-sectional, carried out at the physiology department Northwest School of Medicine Peshawar. The study duration was six months from January 2022 to June 2022. After an overnight fast (12–14 hours), 2.5ml of venous blood was drawn into a sodium fluoride and EDTA tube. This blood was used to measure the fasting plasma glucose (FPG). Insulin levels were determined by concurrently drawing 2.5 ml of venous blood. A separate proforma was used to input all the data. On SPSS 23, all data were entered and examined. Results: In our study, totally 180 patients participated. The mean age with ±SD was 26±4.23 years. The overall frequency of insulin resistance observed in our study was 117 (65%). A statistical significant association was observed between BMI of ≥25 and insulin resistance (p=0.021). Conclusions: Our study concludes that the frequency of insulin resistance in polycyclic ovarian syndrome is high. A statistical significant association was observed between BMI of ≥25 and insulin resistance in our study. Keywords: Insulin resistance; BMI, polycyclic ovarian syndrome
Clinico-Pathological Features of Chronic Myelocytic Leukemia (CML) in Patients Presenting at A Tertiary Care Center
Authors: Arooj Hira , Qureshi Hamida , Roghani Asfandyar Shah , Khan Khalid , Malik Saira Nasr , Syed Saliha
Published: January 2023

Introduction: Chronic myelocytic leukemia (CML) is a slow growing disorder marked by excessive proliferation of cells of myeloid origin which do not lose their capacity to differentiate. Because of unavailability and un-affordability of such markers in most of our tertiary care centers, it is important to have a better understanding of clinical and hematological insight of this disease. Objective: To determine the clinical and hematological features of chronic myelocytic leukemia on bone marrow examination and trephine biopsy Material and method: The current study was cross-sectional study carried out at the Department of Hematology, Hayatabad medical complex, Peshawar from 8/4/2021 to 8/10/2021. In this study a total 196 patients were observed. The findings of bone marrow aspirate for morphology and phase of the disease, along with the trephine biopsy for bone marrow fibrosis were noted. All data with the demographic information like name, age, gender, occupation for further analysis were recorded. Results: In the current study, totally 196 patients were included. There were 112(57%) male patients and 84(43%) patients were female in our study. Based on clinical features and hematological features of patients with chronic myelocytic leukemia, 153(78%) patients had splenomegaly, 102(52%) patients had fever, 192(98%) patients had leukocytosis, 94(48%) patients had anemia. Conclusion: Our study concludes that the frequency of clinical and hematological features i.e. splenomegaly was 78%, fever was 52%, leukocytosis was 98%, anemia was 48% in patients presenting with chronic myelocytic leukemia. Keywords: clinical and hematological features, chronic myeloid leukemia.
Celiac Disease Diagnosis Via Histopathological Correlation of Duodenal Biopsies in Children
Authors: Ullah Muhammad Sami , Angbeen Maira , Tanvir Amna , Zaman Muhammad Haidar , Hussain Sohail , Sarwar Urwa
Published: January 2023

Aim: The purpose of this study is to compare the diagnostic accuracy of duodenal bulb biopsies to distal duodenal biopsies in patients suspected of having celiac disease. Study Design: Cross-sectional study Place and Duration: This study was conducted at Department of Pathology, The children's hospital & The institute of child health, Multan during the period from April, 2022 to September, 2022. Methods: Total 86 children of celiac disease were presented in this study. Informed written consent provided by parents of children for the collection of detailed demographic data. Under general anaesthesia, a duodenal bulb sample and four distal duodenum samples were collected during an upper gastrointestinal endoscopy. Histological alterations indicative with CD were identified. Histological diagnosis and grading were performed using a modification of the Marsh-Oberhuber classification. The entire data set was analyzed by using SPSS 20.0. Results: Forty nine (56.97%) patients were females and 37 (43.03%) cases were males. Children’s mean age was 6.4±3.27 years with mean weight 15.9±6.19 kg. Mean height of the cases was 94.7±10.42 cm. There were 51 (59.3%) children had urban residency. According to marsh grading, 50 (58.1%) cases had grade IIIC. We found that frequency of crypt hyperplasia, influx of immune cells in lamina propria and enterocytes change in both duodenal bulb and distal part biopsies were equal while only frequency of villous atrophy and intraepithelial lymphocytes were different in both biopsies. 96.5% patients reported a high level of correlation, while only 3.5% reported no correlation. Conclusion: Both biopsy sites agree strongly. We may now suggest duodenal bulb biopsy alone. Since the endoscopic method of distal duodenum is laborious and requires more knowledge and time, obtaining biopsies from the proximal section is easier and requires less experience, therefore this strategy may be used even at facilities with junior paediatric gastroenterologists. Keywords: Celiac disease, Children, Histopathology, Duodenal bulb, Distal duodenum
Role of CRP in Evaluating Acute Abdominal Pain: An Observational Study
Authors: Azhar Raheel , Ramzan Raazia , Aslam Saad , Jabbar Jassim , Karim Madiha , Malik Ovais
Published: January 2023

Background:C-Reactive Protein (CRP) is an acute phase reactant that is routinely used in evaluation of cases with acute abdomen. We determined levels of CRP in patients with surgical causes that were either treated with operative or with non operative measures, and patients with non-specific abdominal pain. Objective: The aim of this study was to identify the use of C-reactive protein in differentiating between surgical causes of acute abdomen and non specific abdominal pain. Study Design:This is a prospective observational cohort study. Methodology: This study was conducted in General Surgery Department of Dow University Hospital, Ojha Campus, Karachi from January 2022 till October 2022. A total of 116 patients admitted with acute abdomen via Emergency were included in this study. Results: A total of 7 patients had non specific abdominal pain whereas the remaining 109 patients had surgical causes. 57 of those patients were managed conservatively while 52 underwent surgical interventions. Median value of CRP turned out to be 50, however CRP levels of the three groups had no significant impact on the evaluation of acute abdomen. Practical Implications: CRP levels are actively monitored in patients with acute abdomen. This study was conducted to find out if CRP levels can help assess the treatment of choice in such patients. The end result showed that CRP alone isn’t a helpful parameter to assess patients with acute abdomen. Conclusions: CRP is not a reliable marker in determining whether the patient has surgical abdominal pain or a non specific one. There is still room for further analysis to look for acute inflammatory markers that could help us evaluate the cause behind abdominal pain and guide us in devising a management strategy for the same. Keywords: CRP, C-reactive protein, Acute Abdomen, Non specific abdominal pain, operative intervention, non-operative intervention.
Study Finds Racism; Causes Black Americans and Asians Brain to Age Faster than of other Races, Increasing Dementia Risk
Authors: Yousuf Tanveer , Shahid Qurrat Ul Ain , Hamdan Tafheem Malik Muhammad , Kanwal Marium , Ahmed Areeba
Published: January 2023

Objective: This review aimed to find the racism and its effect on occurrence of dementia and treatment of dementia patients. It was observed that Asian and black American brain ages faster than the other races. Recent findings: The incidence of dementia or the ageing of brain was compared in different studies it was found that the black Americans and non-Hispanic white population had more cases of dementia as compared to white Americans. 2000 US consensus was taken as a standard and age adjusted incidence rate was calculated in different studies. In the general population the prevalence of dementia is higher among African American but lower among the Japanese American. The most recent studies of racial and ethnic difference in dementia incidence were limited to specific geographical areas. The well-known dementia is Traumatic brain injury (TBI), including mild TBI. The females veterans over 55 are particularly rise sharply in coming years. The ageing and dementia research community has identified different risk factors. The medical, lifestyle factors and genetic factors affect the dementia risk. The study discovered that blacks were 65 percent more likely than white Americans to develop dementia. The demographic factors like medical comorbidities, and psychiatric conditions are also have impact on dementia incidence. Summary: The study showed that the ageing of brain takes place early in case of non-white population as compared to white. The cases of dementia and the mortality rate of the patients are higher in case of non-white/black American. There is need to identify the factors that lead to this geographical distribution of disease. Keywords: dementia and Asian American adults.
Unit Xgamma Distribution: Its Properties, Estimation and Application
Authors: Hashmi Sharqa , Ahsan-ul-Haq Muhammad , Zafar Javeria , Khaleel Mundher Abdullah
Published: January 2023

A new one-parameter model for unit-interval datasets is introduced. The proposed distribution is termed “Unit Xgamma distribution.” Some mathematical properties of the new distribution are derived. We also characterize it using truncated moments and a hazard function. Maximum likelihood, least-squares, weighted least-squares, Anderson- Darling, Cramer-von Mises, and maximum product spacing are among the five estimation methods used to estimate the parameter. A Monte Carlo simulation was used to test the efficacy of these developed estimators. The flexibility of the proposed distribution was assessed using water capacity data. The proposed unit Xgamma distribution can be used for bounded datasets as an alternative to the well-known competitive distributions available in the literature.
Higher Order Modeling of Reactor Regulating System and Nonlinear Neural Model Predictive Controller Design for a Nuclear Power Generating Station
Authors: Malik Arshad H. , Memon Aftab A. , Arshad Feroza
Published: January 2023

In the existing instrumentation and control system of an operating Pressurized Heavy Water Reactor (PHWR) based nuclear power plant, conventional controllers are used to control the reactor power. A new idea of Nonlinear Neural Model Predictive Controller (NNMPC) is introduced in this research work. The new 17th order nonlinear higher order model of Reactor Regulating System (RRS) is developed under different plant operating modes and various parametric conditions in Single Input Multi Output (SIMO) configuration with special emphasis on Helium Control Valve Dynamics (HCVD) and Coupled Nonlinear Iodine and Xenon Dynamics (CNIXD). The SIMO RRS model is developed based on first principle. The 17th order model is reduced to 9th order lower dynamic model using Balanced Truncation Method (BTM). The Reduced Order SIMO RRS (RO-SIMO-RRS) model is programmed, simulated and validated in SIMULINK environment. The plant Neural SIMO RRS (N-SIMO-RRS) model is developed using innovative data generated from RO-SIMO-RRS simulations. The plant neural N-SIMO-RRS model is optimized using Levenberg-Marquardt Algorithm (LMA). Using the identified N-SIMO-RRS model, the Nonlinear Neural Model Predictive Controller (NNMPC) is designed, trained, verified, validated, and finally optimized using the backtracking technique in the SIMULINK environment. The optimized results are obtained from designed closed loop RRS and found within the acceptable design limits. The performance of the proposed closed loop RRS is also tested in reference tracking mode with excellent fast tractability near the optimal target demanded power level.
Economical Synthesis of Nitrophenols under Controlled Physical Parameters
Authors: Hussain Shabbir , Ahmad Muhammad Ameen , Ahmad Muhammad , Nisar Asma , Asghar Amina , Suleman Muhammad , Barkaat Samra , Riaz Muhammad , Nasir Muhammad
Published: January 2023

Current studies were performed to find an economical path for the synthesis of nitrophenols which are plant growth regulators (PGR) and are applied to crops for better agricultural production. The study discourages the involvement of costly surfactants such as CTAB, TBAB, H-β and γ-alumina catalysts in commercial production of nitrophenols. This synthesis requires the lower number of chemicals, less time and does not involve the advance instruments. Phenol and its derivatives were selectively nitrated into o/p nitrophenols economically by controlling only the physical parameters, i.e., dilution of nitric acid, reaction time and reaction temperature. The synthesised products were characterised by RP-HPLC and gas chromatography. The reaction between 98% phenol and 32.5% nitric acid at a temperature of 20°C (±2°C) required only 1 hour for optimum yield (91%) of nitrophenols with 77% ortho and 14% para selectivity and was found to have the most suitable route for economical production. The investigated synthetic path is relatively clean and environmentally friendly as it does not involve catalysts and solvents, like the conventional processes. This process may be adopted for commercialisation and industrial level production of nitrophenols for agricultural purposes.
Evaluation of Electric Field for a Dielectric Cylinder Placed in Fractional Space
Authors: Akbar M. , Shahzad M. Imran , Ahmed Saeed
Published: January 2023

The problem related to the dielectric cylinder placed in non-integer dimensional space (FD space) isthoroughly investigated in this paper. The FD space describes complex phenomena of physics and electromagnetism. We have solved Laplacian equation in FD space to obtain the solution of a dielectric cylinder in low frequency. The problem is solved by the method of separation of variables analytically. The classical solution of the problem can be easily recovered from the derived solution in non-integer dimensional space.
Bibliometric Analysis of Proceedings of the Paksitan Academy of Sciences: Part B from 2016 to 2021
Authors: Hassan Waseem
Published: January 2023

Proceedings of the Pakistan Academy of Sciences: Part B (Life and Environmental Sciences) is the official flagship journal of the Pakistan Academy of Sciences. It publishes in the fields of agricultural, biological, environmental and health sciences. Scopus database is directly covering it since 2016 and till 19th April 2022, it has published 210 research documents majorly comprising of articles (n=141), book chapters (n=36), conference papers (n=26), reviews (n=6) and one (n=1) note. It also received 232 total citations. We extracted the publication data from Scopus in BibTeX format and analyzed it on R-Studio. In all publications, 313 authors from 278 institutes or universities from 14 Asian, 6 European, 2 Middle East, 1 Oceanic (Australia), 2 North American, 1 South American (Brazil) and 3 African countries have contributed. The country co-authorship network (constructed on Vosviewer) is presented in Supplemnetaty data (Figure 1). The lists of all authors (with total publications (TP), total citations (TC), publications years, h-index, g-index and m-index), all universities (with TP) and countries (with TP) are provided in supplementary data (Table 1, 2 & 3). It has achieved considerable CiteScore (0.6), SJR (0.143) and SNIP (0.347) calculated on 05th May 2022 by Scopus for the year 2021. The success could be attributed to the editorial board (which has experts from Pakistan, Australia, Canada, China, USA, Turkey, Oman, Malaysia, and Indonesia), reviewers, authors, and editorial management. The number of publications, citations and its foothold in different countries confirm that the journal’s reputation is significantly improving
Genetic Analysis of Restriction Fragment Length Polymorphism of TLL1 Gene (rs17047200) in Patients of Hepatocellular Carcinoma
Authors: Saima Sharif  , Sadia Ashraf  , Shagufta Naz  , Sher Zaman Saf  , Muhammad Saqib
Published: January 2023

To find out the association of polymorphism of the TLL1 gene in hepatocellular carcinoma. A cross-sectional study was conducted from January 2020 to September 2020. Subjects were enrolled from Mayo Hospital, Lahore, Jinnah Hospital Lahore and the Liver Transplant Unit of Sheikh Zayed Hospital, Lahore. A total of 200 individuals were registered and segregated into the Control group (n=100) and hepatocellular carcinoma (HCC) group (n=100). DNA was extracted from obtained blood samples and Restriction Fragments Length Polymorphism (RFLP) was carried out at the laboratories of LCWU by using specific primers and restriction endonuclease enzymes. The data were analyzed statistically. The high proportion of smoking, hepatitis B, hepatitis C, cirrhosis and Body Mass Index (BMI) were established risk factors in the HCC group. Subjects with hepatocellular carcinoma had low socioeconomic status. Heterozygous bands in the HCC group were observed after RFLP. TLL1 genotype was AA (72 %) and AT/TT (28 %). The patient’s clinical aspects were similar across TLL1 genotypes. It was concluded that RFLP on the exon region by using their specific enzymes HpyCH4III showed heterozygous bands in the HCC group that indicated a mutation in the TLL1 gene though this mutation does have a significant association with HCC.
Response of Rangeland Vegetation to Recent Trends in Seasonal Climate in Mansehra, Pakistan
Authors: Fatima Naheed , Kausar Rukhsana , Ashraf Arshad , Iqbal Muhammad Bilal , Nawaz Qurat-ul-Nain
Published: January 2023

The deterioration of rangeland resources as a result of environmental changes is a serious concern in the Himalayan mountainous region of Pakistan. The present study is aimed to evaluate the response of vegetation cover of rangeland to recent trends in climate parameters, such as the seasonal temperature and rainfall in the Mansehra district of Khyber Pakhtunkhwa province, Pakistan. Correlation analysis was performed between the MODIS data products, i.e., NDVI (Normalized difference vegetation index) and LST (Land surface temperature), and TRMM rainfall datasets of the 2000-2018 period. NDVI indicated a negative correlation with LST of winter (R= -0.56), spring (R= -0.7), summer (R= -0.24), and autumn (R= -0.23) significant (p<0.05) for winter and spring seasons only. In contrast, the correlation of NDVI was observed positive with seasonal rainfall exhibiting coefficient of correlation values of 0.41, 0.79, 0.64, 0.7 for winter, spring, summer, and autumn significant (p<0.05) for the last two seasons only. The low correlation observed between NDVI and LST of summer and autumn seasons is likely because of the prevailing stress condition of chlorophyll contents of the vegetation cover under warming conditions. However, this situation appears to be compensated by the rainfall as indicative of the moderate to strong correlation between the NDVI and rainfall of these two seasons. The least NDVI values observed during the winter season indicate limited vegetation cover for grazing opportunities in the lower valleys. However, an in-depth investigation of production patterns would further facilitate analyzing the grazing potential to support decision-making for long-term grazing management.
How to Lose a Musical Compass in a Few Hundred Lines? (And How to Find it again?)
Authors: Bodnár Gábor
Published: January 2023

This paper attempts to explain the collective incomprehensibility of The Waste Land. Of course, this attempt does not only apply to the music of Anthony Burgess, since, for one, it is inseparable from the poetry of T. S. Eliot, and it also multiplies the number of quotations and associations in the literary work, be it obvious or more or less hid- den. Therefore, this paper will embark on a special task: through the compositional methods of a nineteenth-century composer, Robert Schumann, it will try to demon- strate the real and metaphorical ambiguity of the tonality resulting from fragmenta- tion, creative and playful musical gestures, and the various personae—this method may help to find an individual way to experience the effect of Burgess’s music.
Imperfect Man
Authors: Burgess Anthony
Published: January 2023

The AnaChronisT would like to express the editors’ sincerest gratitude to the International Anthony Burgess Foundation in Manchester and director Prof. Andrew Biswell for giving us permission to publish this most valuable essay for the first time. The only changes made by the editors were some very minor corrections concerning a few obvious typographical errors and the standardisation of certain recurring expressions.
Lilies that Fester
Authors: Farkas Ákos , Laverycheva Evgeniya
Published: January 2023

This article endeavours to examine Burgess’s mid-career novel, The Clockwork Testament, to establish whether the third instalment of the “Enderby Quartet” can, or indeed should, be reclassified as a piece of academic fiction. What is at stake here is not only a matter of generic taxonomy but also the question of how such a possible reclassification could impact our understanding of Burgess’s thematic and stylistic preoccupations and how, in a broader sense, this particular novel of his fits into an important segment of twentieth-century English-language fiction highlighted by the names of Kingsley Amis, David Lodge, or Philip Roth. Informed by theoretical insights gained from the works of Michel Foucault, Elaine Showalter, and others, this piece could also make a notable contribution to what is known as the poetics of place on the one hand and our knowledge concerning the writer-environment nexus on the other. Taking a close look at the biographical and historical context in which The Clockwork Testament was written is meant to suggest the ethnic, cultural, and sociological tensions that beset the refurbishing of higher education in America at the time. All in all, the authors offer their answer to the question whether The Clockwork Testament is a campus novel in any meaningful sense of the word and, if so, what that tells us about Burgess and his fictional excursion into academia.
Beyond Nadsat
Authors: Clarke Jim
Published: January 2023

Anthony Burgess is best-known for his 1962 novella, A Clockwork Orange, which is famously written in Nadsat, the invented language of the protagonist Alex and his gang of droogs. Burgess’s invention of Nadsat has gone on to inspire the proliferation of invented languages in fiction, especially in Science Fiction. Just as Burgess’s other fictions are less well-known, however, so too are his other forays into invented literary languages. Burgess spent almost the entirety of his career exploring the parameters of invented language in his fiction, and this article aims to describe and taxonomise these many linguistic inventions.
Characteristics of Patients Administrated Thrombolytics in the Emergency Department
Authors: ERASLAN Ahmet Tolga , SELVİ Fatih , BEDEL Cihan , BALTACIOĞLU Muhammed , YILDIZ Günay
Published: January 2023

Objective: Arterial and venous thromboembolism is one of the most prevalent diseases and related to ischemic stroke, pulmonary embolism, and myocardial infarction leading to mortality or morbidity. Fibrinolytic therapy is the most profound lifesaving therapy in these diseases. We aimed to evaluate the demographic features and post- tissue plasminogen activator (tPA) period of patients administered fibrinolytic in the emergency department (ED). Materials and Methods: This retrospective study was conducted with patients instituted fibrinolytic therapy in the ED between January 2018 and July 2021. Age and gender of the patients, vital signs, laboratory tests, comorbidities, drugs used, lifesaving therapies secondary to the present pathology, tPA complications, mortality and similar presentations within the six months period were recorded to the study form. Results: A total of 277 patients were included into the study. Ischemic stroke was the most prevalent disease entailing the institution of tPA (n=252; 91%). The study patients mostly used antihypertensives (n=155, 56%), followed by anti-aggregants (n=101, 36.5%). Intracranial hemorrhage (11.9%) was the most frequent complication secondary to tPA and the study patients had mostly undergone thrombectomy as a lifesaving therapy (n=34, 12.4%). The univariate analysis revealed that antiaggregant usage (n=21, 53.8% vs n=80, 33.6%; p=0.01), systolic blood pressure (160 mmHg, IQR: 138-190 vs 150 mmHg 130-169; p=0.02) and diastolic blood pressure (90 mmHg, IQR: 75-100 vs 83 mmHg, IQR: 72-94; p=0.03) differ between the patients with and without a post-tPA hemorrhage. Conclusion: According to the results of this study, ischemic stroke is the main pathology related to tPA administration in ED. Hypertension was the most seen comorbidity in study patients, mostly using anti-hypertensive and anti-aggregants. Intracranial hemorrhage was the most prevalent complication owing to tPA use, and systolic and diastolic blood pressures and anti-aggregant use pertain to post-tPA hemorrhages.
A importância da farinha de mandioca para a agricultura familiar e para o desenvolvimento regional local
Authors: Aracaty e Silva Michele Lins , Soares Marlene de Almeida
Published: January 2023

este trabalho tem como objeto de análise a farinha do Uarini, oriunda de um município do interior do Estado do Amazonas com o mesmo nome. Dada a cultura regional bem como o peso da atividade para a região, em 2019 houve o recebimento da Certificação de Origem e Indicação Geográfica (IG), expedido pelo INPI. Para tanto, temos como proposta a análise da importância socioeconômica da farinha do Uarini para a agricultura familiar e para o desenvolvimento regional e local. Para tanto, fez-se uso de pesquisa qualitativa, descritiva e exploratória com dados secundários, de origem bibliográfica e documental para fins de análise de conteúdo. A atividade produtiva oriunda do município do Uarini-AM é fomentadora de desenvolvimento regional e local, contribui para a geração de emprego e renda, fortalece a economia dos municípios adjacentes impulsionando toda a cadeia produtiva, ao mesmo tempo em que contribui para o fomento da agricultura familiar, para a permanência do homem no campo fortalecendo os seus laços com a terra.
Análise comparativa das complicações entre hernioplastia inguinal aberta e laparoscópica
Authors: Silva Octávio Luis Alves da , Magalhães Júnior Antônio de Pádua Freire , Fernandes Afonso Nonato Goes , Lima Neto Heron Kairo Sabóia Sant’Anna , Alves Luísa Lucas , Nobre Lara Poti
Published: January 2023

Aproximadamente 300 mil procedimentos cirúrgicos são realizados no Brasil anualmente para correção de hérnia inguinal. Diversas formas terapêuticas foram desenvolvidas no decorrer da história, sendo a comparação entre as hernioplastias convencionaise as videolaparoscópicas as técnicas mais discutidas. O presente artigo buscou comparar a experiência com o tratamento laparoscópico e convencional na abordagem das hérnias inguinais em um hospital secundário da rede pública de Fortaleza-CE. Realizou-se estudo descritivo, observacional e retrospectivo, através da coleta de dados de prontuário de 46 pacientes do Hospital e Maternidade José Martiniano de Alencar. Destes, 23 foram submetidos à hernioplastia aberta e 23 à hernioplastia laparoscópica. Os dados coletados foram estudados com o auxílio do programa SPSS da IBM versão 22. Os resultados obtidos com o nosso estudo corroboram com a literatura atual em relação à diminuição de dias de internamento no pós-operatório e de complicações na abordagem laparoscópica em comparação com a aberta.
Hemofilia em paciente com fístula arteriobiliar após ferimento por arma de fogo: relato de caso
Authors: Rolim Neto Ramiro , Siebra Bárbara de Oliveira Brito , Ferraz Lucyano Rocha da Silva , Nobre Caroline Celestino Girão , Aragão Raphael Felipe Bezerra de , Rocha Francisco Eduardo Siqueira da
Published: January 2023

A hemofilia é uma causa rara de hemorragia digestiva e complicação incomum no trauma hepático. Nosso objetivo é relatar o caso de um paciente vítima de trauma toracoabdominal, com ferimento por arma de fogo, apresentando lesão hepática tunelizante do lobo direito ao lobo esquerdo, sendo realizado packing hepático para interromper o sangramento, e reoperado após 48 horas para retirada das compressas. No 22º dia pós-operatório, o paciente apresentou hematêmese, icterícia e dor no quadrante superior direito do abdome. A tomografia computadorizada do abdome revelou pseudoaneurisma de um ramo da artéria hepática direita, associado a uma fístula arteriobiliar. Foi feito o diagnóstico de hemobilia e a fístula foi embolizada por arteriografia hepática.
Ressecção videolaparoscópica de endometrioma de parede abdominal com reconstrução com tela
Authors: Gomes José Walter Feitosa , Chaves Francisco Nogueira , Nogueira Lucas Ribeiro , Cunha Carlos Magno Queiroz da , Dantas Anna Beatriz Viana Cardoso , Araújo Victor Andrade de
Published: January 2023

A endometriose de parede abdominal é uma afecção rara e tem incidência de 0,03% a 4%. Sua ocorrência é geralmente associada a manipulações uterinas em cirurgias abdominais, como cesáreas e histerectomias. Apresentamos aqui caso de endometriose de parede abdominal onde sua exérese, bem como a reconstrução da parede, foi realizado via laparoscópica. Desse modo, propiciando menor trauma cirúrgico, melhor visualização de outras possíveis lesões endometrióticas na cavidade abdominal e melhor resultado estético.
Numerical convergence of a Telegraph Predator-Prey system
Authors: Luiz Kariston Stevan , Organista Juniormar , Cirilo Eliandro Rodrigues , Romeiro Neyva Maria Lopes , Natti Paulo Laerte
Published: January 2023

Numerical convergence of a Telegraph Predator-Prey system is studied. This partial differential equation (PDE) system can describe various biological systems with reactive, diffusive, and delay effects. Initially, the PDE system was discretized by the Finite Differences method. Then, a system of equations in a time-explicit form and in a space-implicit form was obtained. The consistency of the Telegraph Predator-Prey system discretization was verified. Von Neumann stability conditions were calculated for a Predator-Prey system with reactive terms and for a Delayed Telegraph system. On the other hand, for our Telegraph Predator-Prey system, it was not possible to obtain the von Neumann conditions analytically. In this context, numerical experiments were carried out and it was verified that the mesh refinement and the model parameters, reactive constants, diffusion coefficients and delay constants, determine the stability/instability conditions of the discretized equations. The results of numerical experiments were presented.
Carbonation of concretes containing LC³ cements with different supplementary materials
Authors: Balestra Carlos Eduardo Tino , Savaris Gustavo , Nakano Alberto Yoshihiro , Schneider Ricardo
Published: January 2023

Due to the clinkerization process during the Portland cement production, large amounts of CO2 are emitted, increasing the effects related to climate change (approximately 5-10% of global CO2 emissions come from cement production), consequently, the seek for alternatives to mitigate these high emissions are necessary. The use of supplementary cementitious materials (SCM) to partial replace of Portand clinker/cement has been the subject of different research, including the use of LC3 cements (Limestone Calcined Clay Cements), where up to 50% of Portland clinker can be replaced, however, cement industry has already used othersupplementary cementitious materials with pozzolanic activities in commercial cements. In this sense, this work evaluates the performance of concretes containing LC3 mixtures with the presence of different SCM (silica fume, fly ash, sugarcane bagasse ash and açaí stone ash) regarding durability issues by carbonation. The results showed that all concretes with LC3 presented higher carbonation fronts in relation to the reference concrete, with Portland cement, due to the lower availability of calcium to react with the CO2 that penetrates into the concrete pores, so the adoption of curing procedures and coatings are recommended.
İslami Bankacılık Gelişimi ile Gelir Dağılımı İlişkisi, Malezya Örneği
Authors: İŞLEMEZ İbrahim , ASLAN Hakan
Published: January 2023

Gelir dağılımında adaletin sağlanabilmesi her devletin en öncelikli görevleri arasında yer almaktadır. Bugün gelir dağılımını etkileyen en önemli unsurlardan biri de finansal sistemin en önemli sac ayağı olan bankacılık sistemidir. Ekonomilerde geleneksel bankacılık sistemine alternatif olarak faizsizlik ilkesiyle faaliyet gösteren İslami bankaların gelişim ve derinliklerinin artmasıyla birlikte zamanla finansal piyasalardan daha fazla pay almaya başlamışlardır. Bu durum İslami bankacılık gelişiminin gelir dağılımına olan etkisinin incelenmesi gereksinimini ortaya çıkarmakla beraber literatürde bu tür çalışmaların az olması dikkat çekicidir. Bu çalışmada İslami bankacılık gelişiminin gelir dağılımı üzerindeki etkisi Malezya özelinde ARDL sınır testi yöntemi ile 2001-2019 dönemi için incelenmektedir. Çalışmanın ekonometrik bulgularına göre kişi başına düşen milli gelir ekonomik gelişmenin ilk dönemlerinde gelir dağılımı eşitsizliğini azaltırken ekonomik gelişmenin ilerleyen safhalarında gelir eşitsizliğini artırmaktadır. Bu çalışmanın esas motivasyon kaynağını oluşturan, İslami bankacılık gelişiminin gelir dağılımı ilişkisine bakıldığı zaman, İslami bankalar tarafından özel sektöre kullandırılan finansman hacminde meydana gelen ortalama %1’lik bir artışın gelir eşitsizliğini ortalama %0,036 oranında azalttığı tespit edilmiştir. Bu doğrultuda gelir dağılımındaki adaletin sağlanmasında olumlu katkı yapan İslami bankacılık sisteminin doğru tanıtılması, geliştirilmesi ve derinleştirilmesi tavsiye edilmektedir. Ayrıca kamu otoritelerinin İslami bankacılığın gelişmesinde ve derinleşmesinde etkin bir rol alındığı takdirde İslami finansın hızlı bir gelişim gösterebileceği ve bu durumun gelir eşitsizliğini azaltmada önemli bir rol oynayabileceği ifade edilmektedir.
Self-Healing Concrete by Microorganisms in the Altered Pozzolan of Madagascar with Calcium from Crab Wastes
Authors: Andriamanalina Toavina M , Andrianandrasana Martial Doret , Raharison Maxime , Andrianarison Edouard Ravalison
Published: January 2023

Concrete is at a high risk of cracking which threats its durability. Self-healing bacterial concrete has been developed in recent years to tackle this issue and its effectiveness has been massively studied. However, bacteria need carriers and expanded clay is the most used as such, but it reduces concrete strength. Moreover, bacterial culture and immobilization processes are highly expensive; calcium salts also contribute to the high cost of this type of concrete. This work therefore aims to overcome these limitations. Calcium salts were collected from the chitosan production process from crab waste. In addition, we noticed that Betafo pozzolan contains an abundant number of microorganisms, and for the first time, we discovered that those microorganisms have polyextremophilic characters, are resistant to various sterilization methods, and allow the self-healing concrete process. We concluded that calcium salts from the crab, with those microorganisms are able to heal crack up to 350 µm wide, reducing the expenses related to nutrients, and eliminating those related to the growth and the immobilization of bacteria on carrier. Moreover, we pointed out that pozzolan significantly increases compressive strength by 90.04%. However, the behavior of those microorganisms and the pozzolanic reactions need to be further investigated.
Kết quả tạo hình vú tức thì bằng túi độn điều trị ung thư vú giai đoạn sớm tại Bệnh viện K
Authors: Đỗ Đình Lộc , Vũ Quang Vinh
Published: January 2023

Mục tiêu: Đánh giá kết quả tạo hình vú tức thì bằng túi độn trong điều trị ung thư vú giai đoạn sớm.Đối tượng và phương pháp nghiên cứu: Mô tả hồi cứu trên 62 bệnh nhân ung thư vú được phẫu thuật cắt tuyến vú tiết kiệm da hoặc bảo tồn núm kết hợp đặt túi từ tháng 1/2015 đến tháng 12/2021 tại khoa Ngoại Vú, Bệnh viện K.Kết quả: Tỷ lệ biến chứng sau mổ thấp. Điểm thẩm mỹ ở mức đẹp và tốt ngay sau mổ, sau mổ 1 tháng, 1 năm, 2 năm, 4 năm lần lượt là 96,8%; 93,5%; 69,4% và 43,5%. Điểm thẩm mỹ sau mổ giảm theo thời gian. Nhóm xạ trị bổ trợ có điểm thẩm mỹ thấp hơn nhóm không xạ trị (p < 0,05). Hóa chất không ảnh hưởng đến kết quả thẩm mỹ của phẫu thuậtKết luận: Tái tạo tuyến vú một thì bằng túi độn cho kết quả thẩm mỹ tốt, an toàn, có sự suy giảm tính thẩm mỹ theo thời gian và nhóm điều trị xạ trị bổ trợ.
Đánh giá kết quả điều trị gãy lồi cầu xương hàm dưới gập góc tại Khoa Phẫu thuật hàm mặt - Tạo hình - Thẩm mỹ, Bệnh viện Hữu nghị Việt Đức
Authors: Đào Văn Giang , Nguyễn Thị Thanh , Trần Thị Thanh Huyền
Published: January 2023

Mục tiêu nghiên cứu: Đánh giá kết quả lâm sàng điều trị gãy lồi cầu xương hàm dưới gập góc tại Bệnh viện Hữu nghị Việt Đức.Đối tượng và phương pháp nghiên cứu: Những bệnh nhân gãy lồi xương hàm dưới gập góc từ tháng 6/2020-12/2021. Nghiên cứu mô tả cắt ngang, hồi cứu.Kết quả: Tuổi trung bình 32,0  14,1 tuổi; tỉ lệ nam/nữ: 18/7, nguyên nhân tai nạn giao thông chiếm 24/25 bệnh nhân (96%). Thời điểm 6 tháng sau phẫu thuật có 95% bệnh nhân (BN) khớp cắn đúng, mức độ há miệng tối đa trung bình là 4,125  0,42cm, có 1 bệnh nhân bị yếu nhẹ nhánh bờ hàm thần kinh VII.Kết luận: Điều trị nắn chỉnh kết hợp xương trong điều trị gãy lồi cầu gập góc (có thể hỗ trợ bằng nội soi) đã đem lại kết quả điều trị tốt cho bệnh nhân, tỉ lệ thành công cao, ít nguy cơ biến chứng.