bluuebunny/crossref_metadata_2025 huggingface dataset:
PROTECTIVE AND THERAPEUTIC EFFECTS OF PROPOLIS AGAINST MONOSODIUM GLUTAMATE (MSG) TOXICITY IN RAT BRAIN: HISTOPATHOLOGICAL STUDY
Authors: Gheth Ebtesam, M. M. , Eldurssi Ibrahim, S.
Published: February 2023

Monosodium glutamate (MSG) is the salt of nonessential glutamic acid. It has a property to enhance the perception that flavors are well blended and full-bodied. Propolis is a resinous substance collected by honeybees from the bud and bark of certain trees and plants. It has been used in folk medicine from ancient times in many countries. The present study aimed to investigate the protective and curative effect of propolis against MSG on the rat brain. Accordingly, fifty male albino rats were divided into five groups. The first group served as control, whereas the second group was administered propolis at an oral daily dose of 200 mg/kg b. w. for eight weeks. The third group received MSG 1 g/kg b. w. for eight weeks. The fourth group (protective group) was initialy administered with propolis alone for 4 weeks, and followed by MSG in association with propolis for 4 weeks. The fifth group (therapeutic group) was first given MSG alone for 4 weeks and secondly administered propolis in association with MSG for 4 weeks. At the end of four and eight weeks, brain tissues were collected for histopathological study purposes. Histopathological studies of MSG-treated rats displayed deleterious alterations in brain tissues as indicated by perivascular oedema and cuffing. Some blood vessels were congested and there was vacuolation of some neurons. The protective group showed gliosis in the cerebrum. There were still some odematous changes and perivascular cuffing which were still persistent. Propolis extract in the curative group caused active hyperaemia of the brain, blood vessels were congested and showed perivascular oedema and some neurons exhibited a marked vacuolation. It may be concluded that the results confirm the toxic effect of MSG on the brain and the protective effect of propolis, especially when administrated as a propolis alone.
ON USING NONPARAMETRIC REGRESSION METHODS TO ESTIMATE CATEGORICAL OUTCOMES MODELS WITH MIXED DATA TYPES
Authors: Mami Ahmed M. , Elberjo Ayman Ali
Published: February 2023

Many data analysis methods are sensitive to the type of data under study.  When we begin any statistical data analysis, it is very important to recognize the different types of data. Data can take a variety of values or belong to various categories, whichever numerical or nominal. However, there are two types of data, quantitative and qualitative (Categorical) data. The general and powerful methodological approaches for the analysis of quantitative data have been widely taught for several decades. While the analysis for qualitative data analysis have blossomed only in the past 25 years. The need for analysis of categorical data techniques has increased steadily in recent years, in economic, health, social science. However, analysis of categorical data models when the dependent variable binary or multinomial outcomes with mixed explanatory variables are complex. The main goal of this paper is to estimate a nonparametric regression model of the binary and multinomial outcomes models with mixed explanatory variables, it is based on nonparametric conditional CDF method and (PDF) method of bandwidth selection, presented by   Li and Racine (2008). Then we have compared it with one of the most common method of parametric regression (the logistic regression model). The comparisons will be based on two criteria depends on their classification ability through Correct Classification Ratio CCR as well as their log likelihood value LLK. We conducted several simulation studies using generated random data (categorical discrete and continues) in order to investigate the performance of both the parametric model and the nonparametric model for binary and multinomial outcomes. Interesting results have been achieved in this work. Application on real-data have also been applied when there exist mixed variables. We make use of dataset of the Household Expenditure Survey (HES).
PROTECTIVE EFFECTS OF Β-GLUCAN AND G-CSF ON THE PHYSIOLOGICAL ALTERATIONS INDUCED BY CYCLOPHOSPHAMIDE IN MICE
Authors: Mohamed Dr. Idriss H.
Published: February 2023

Cyclophosphamide (CTX) is a DNA alkylating chemotherapeutic agent, causing hepatocytes injury. Granulocyte colony stimulating factor (G-CSF) promotes granulocyte counts and antioxidants to increase. This study aimed to investigate the effect of certain natural products such as β- glucan from medicinal fungi as adjuvant systems to reduce toxicity of chemotherapy, enhance the effects of G-CSF to mobilize stem cells and improve the quality of hepatocytes functions. Naïve mice were injected with CTX, G-CSF and β-glucan for five days then physiological parameters were measured. The results showed that CTX administration decreased the parameters of red blood cell distribution width (RDW) counts and total white blood cells)WBC( count. Furthermore, CTX administration has hepatocyte oxidative stresseffectwhich is characterized by increasing prooxidants xanthine oxidase (OX), thiobarbituric acid-reactive substances (TBARS) and decreasing of antioxidants glutathione peroxidase (GPx).As a result, hepatocytes injury, characterized by elevating of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities occurred. The treatment of mice with G-CSF and β-glucansuccess fully normalized the physiological parameters by returning WBCs, RDW and lymphocytes counts to normal levels, hepatocytes oxidative stress characterized by decreasing Prooxidants OX,TBARS and increasing antioxidants GPx reflected by significant decrease in the serum activities of AST and ALT activities.
SIGNET-RING CELL CARCINOMA METASTASIZED INTO THE MENINGIOMA: A CASE REPORT
Authors: Goret Ceren Canbey , Erkan Murat , Dogan Meryem
Published: February 2023

Metastasis of extracranial malignant neoplasms to meningioma seen very rare (“tumor to tumor metastasis”). Metastasis to meningiomas are most frequently primary tumors of the breast and lung, while metastasis from the kidney tumors, thyroid, and uterus endometrium and even from melanomas have also been reported (1-5). According to our knowledge; this case, signet-ring cell adenocarcioma infiltration in a small focus within the intracranial meningothelial meningioma seems first in the literature.
CONTESTATION DE LA GOUVERNANCE DU PARC NATIONAL DE LA GARAMBA PAR LES ORGANISATIONS DE LA SOCIETE CIVILE : ANALYSE ET DEFIS.
Authors: Madrandele Peter Talaguma
Published: February 2023

Les Organisations de la société civile des territoires de Dungu et Faradje remettent à cause la gouvernance du Parc National de la Garamba à travers plusieurs mémorandums.

L’exclusion des communautés riveraines dans toutes les étapes de conception des projets, de leurs exécutions ainsi que de leurs évaluations constituent la raison principale qui envenime l’interaction conviviale entre les parties en présence. Plus ou moins quatre ou cinq mémorandums ou lettres de protestations ont été adressés aux gestionnaires du Parc dénonçant notamment l’absence d’un cadre permanent de concertation pouvant régir les rapports entre les communautés riveraines et les gestionnaires du Parc National de la Garamba.

La technique documentaire et les échanges avec certaines personnes ressources  à Nzopi, Miwara, Awago, Tadu, Zoro, Kpodho, Faradje-centre, Djabir, Kuruphata, Aba, Tekadje, Missa, Nagero, Gangala Na Bodio et Dungu-centre témoignent que l’absence de ce cadre permanent de concertation contribue à la persistance des conflits.

Il est plus que nécessaire voire urgent qu’il ait que l’effectivité de cadre de concertation tant attendu afin de permettre une gouvernance concertée entre les gestionnaires de cet espace dédié à la conservation et les communautés riveraines.
Asuhan Keperawatan Diare pada Anak dengan Gastroenteritis di Ruang Ar-Rahman
Authors: Nurjanah Putri Aulia , Murniati Murniati , Handayani Rahmaya Nova
Published: February 2023

Latar Belakang: Penyakit gastroenteritis didefinisikan sebagai radang selaput lendir saluran pencernaan yang ditandai dengan diare atau muntah. Penyakit gastroenteritis di Indonesia ini masih menjadi masalah besar, khususnya gastroenteritis yang  disebabkan  oleh  infeksidan  noninfeksi. Gastroenteritis sendiri didefinisikan seperti buang air besar (defekasi) dengan tinja berbentuk cairan atau setengah cair (setengah padat) kandungan air tinja lebih banyak dari biasanya lebih dari 200g atau 200ml/24jam.
Tujuan: Penelitian ini bertujuan untuk menganalisa asuhan keperawatan pada pasien diare dengan gastroenteritis
Metode: Penelitian ini menggunakan metode deskriptif kualitatif berbentuk studi kasus. Asuhan keperawatan diberikan kepada An. D selama 3 hari. Teknik pengumpulan data diperoleh dari hasil wawancara, observasi, dan pemeriksaan fisik.
Hasil: Berdasarkan data yang diperoleh dari analisa data yaitu BAB pasien cair >7x/hari, ampas sedikit, makan minum sedikit dan disertai riwayat demam 3 hari sebelum dibawa kerumah sakit. Pasien terlihat lemas, mukosa bibir kering, terpasang infus RL 80 tpm dengan tanda- tanda vital nadi: 84x/menit, respirasi: 24x/menit, suhu: 36,3 C, SPo2: 97%. Berdasarkan data-data yang diperoleh dari analisa data dapat disimpulkan untuk diagnosa keperawatan pada An. D yaitu diare berhubungan dengan proses infeksi.
Kesimpulan: Setelah melakukan tindakan keperawatan sesuai dengan rencana tindakan kemudian penulis melaksanakan evaluasi tindakan keperawatan pada An. D dan keluarga. Evaluasi tersebut berfungsi untuk menilai tingkat keberhasilan dan intervensi yang telah dilakukan. Hasil evaluasi dapat menyatakan bahwa masalah yang muncul pada An. D teratasi sebagian.
Analisis Faktor yang Mempengaruhi Kunjungan ANC pada Ibu Hamil di Lingkungan Sampora Cibinong Kabupaten Bogor Tahun 2021
Authors: Ginting Eka Rehna Ginta Cintami
Published: February 2023

Latar Belakang: Pemeriksaan ANC terbaru sesuai dengan standar pelayanan minimal 6 kali selama kehamilan. Adanya ibu hamil yang melakukan kunjungan ke dukun beranak di Lingkungan Sampora ini pada K1 (10%) dan K4 (106,7%) sedangkan yang melakukan kunjungan ke medis di K1 (101,6%) dan di K4 (74,7%).
Tujuan: Untuk menganalisis faktor yang mempengaruhi kunjungan ANC pada ibu hamil di lingkungan Sampora Cibinong Kabupaten Bogor.
Metode: Penelitian kualitatif eksploritatif. Informan pada penelitian ini terdiri dari 7 yaitu informan kunci X5-X6 bidan desa dan kader, sedangkan informan pendukung yaitu X1-X4 ibu hami, suami, dan dukun beranak dengan menggunakan pedoman wawancara, mengunakan alat perekam dan dokumentasi.
Hasil: Faktor yang mempengaruhi kunjungan ANC pada ibu hamil di lingkungan Sampora Cibinong Kabupaten Bogor  adalah Pengetahuan, ekonomi, dukungan dan tradisi atau budaya.
Kesimpulan: Pengetahuan dan dukungan kurang mempengaruhi kunjungan ANC pada ibu hamil di lingkungan Sampora Cibinong Kabupaten Bogor, sedangkan ekonomi dan tradisi/budaya sangat mempengaruhi kunjungan ANC pada ibu hamil ke medis dan non medis.
Hubungan Tingkat Adiksi Penggunaan Gadget dengan Kecerdasan Emosional pada Anak Usia Sekolah Dasar
Authors: Sari Seli Prastika , Handayani Yani , Herliana Irma
Published: February 2023

Latar Belakang: Penggunaan gadget yang berlebihan pada anak dapat menimbulkan kecanduan (Adiksi). Dampak negatif dari adiksi gadget yaitu dapat menghambat perkembangan emosi.
Tujuan: Untuk mengetahui hubungan tingkat adiksi penggunaan gadget dengan kecerdasan emosional anak usia sekolah dasar.
Metode: Desain pada penelitian ini menggunakan deskriptif korelasi dengan pendekatan cross-sectional. Dalam penelitian ini teknik pengambilan sampel yang digunakan yaitu nonprobability sampling dengan teknik purposive sampling sehingga jumlah sampel pada penelitian ini adalah sejumlah 52 responden. Instrumen yang digunakan adalah smartphone addiction scale-short version (SAS-SV) dari Kwon et al (2013) dan Trait Emotional Intelligence Questionnaire-Short Form (TEIQueSF) dari Petrides (2006).
Hasil: Dari hasil pengujian uji univariat didapatkan distribusi adiksi gadget kategori tinggi (63,5%) dan kecerdasan emosional rendah (57,7%). Dari hasil uji bivariat didapatkan hasil adanya hubungan tingkat adiksi penggunaan gadget dengan kecerdasan emosional anak usia sekolah dasar dengan p-value 0,000.
Kesimpulan: Semakin tinggi tingkat adiksi gadget maka semakin rendah kecerdasan emosional yang dimiliki pada anak usia sekolah dasar.
IMPLEMENTASI NILAI SUFISTIK DALAM MODEL MANAJEMEN KEPEMIMPINAN KEPALA SEKOLAH MA NU PUTRA BUNTET PESANTREN CIREBON
Authors: Alfayyadl Ahmad Fasya , Lessy Zulkipli
Published: February 2023

According to Roger, there are three elements for an institution or organization to achieve success, namely good leadership, good management, and good teamwork. In this case, schools need to have good leaders or principals in carrying out their duties so that the needs of the school can run well. A good principal can be seen from his or her leadership model. The purpose of this study is to provide an understanding of good and correct leadership models in order to achieve the expected goals. The research method used is a qualitative method with a descriptive approach. Therefore, the researcher used triangulation technique. The result is that there are Sufistic values ​​that are implemented by the principal of the MA NU Putra Buntet Pesantren Cirebon. The Sufistic values ​​are patience, humility, sincerity, istiqamah, wara', responsibility, and pleasure. The conclusion is that if there is a good and right leadership model, it will produce something good and right, as happened at MA NU Putra Buntet Pesantren Cirebon.
Menurut Roger terdapat tiga elemen agar lembaga atau organisasi mencapai kesuksesan, yakni kepemimpinan yang baik, manajemen yang baik, serta kerjasama tim yang baik. Dalam hal ini, sekolah perlu memiliki pemimpin atau kepala sekolah yang baik dalam menjalankan tugasnya agar kebutuhan dan keperluan dalam sekolah dapat berjalan dengan baik. Kepala sekolah yang baik dapat dilihat dari model kepemimpinannya. Tujuan penelitian ini ialah memberikan pemahaman terkait model kepemimpinan yang baik dan benar agar tercapainya tujuan yang diharapkan. Metode penelitian yang digunakan yakni metode kualitatif dengan pendekatan deskriptif. Oleh karena itu, peneliti menggunakan teknik triangulasi. Hasilnya yaitu adanya nilai sufistik yang diimplementasikan oleh kepala sekolah MA NU Putra Buntet Pesantren Cirebon. Nilai sufistiknya yakni sabar, tawadhu, ikhlas, istiqamah, wara’, tanggung jawab, dan rida. Kesimpulannya adalah dengan adanya model kepemimpinan yang baik dan benar maka akan menghasilkan sesuatu yang baik dan benar pula, seperti halnya yang terjadi di MA NU Putra Buntet Pesantren Cirebon.
KEBEBASAN BERAGAMA MENURUT TAFSIR AL-MISBAH AL-QURAN SURAT AL-BAQARAH AYAT 256
Authors: Kuswantoro Kuswantoro , Alfi Imam
Published: February 2023

Freedom of religion is often misinterpreted as freedom not to have a religion or freedom to change religions. This is a miss-interpretation of religious freedom. In Surat Al-Baqarah 256 it states that there is freedom of religion, but the scholars say there is no absolute freedom to change religions, this refers to the Al-Quran mufasir Quraish Shihab. This research method uses library research methods to collect data by means of documentation. The results of the research based on the interpretation of Al Baqarah 256 are that freedom of religion exists in Islam, namely freedom in belief or in religion, people who embrace Islam or other religions may not be on the basis of coercion, but the commentators do not explain freedom to change religions.
Kekebasan beragama sering disalah artikan kebebasan untuk tidak bergama atau kebebasan untuk berpindah-pindah agama. Hal tersebut merupakan kesalahan penafsiran dari kebebasan beragama. Pada Surat Al-baqarah 256 memang menyatakan adanya kebebasan beragama, namun para ulama mengatakan tidak ada kebebasan mutlak untuk berpindah agama hal ini merujuk pada Al-Quran mufasir Quraish Shihab. Metode penelitian ini menggunakan metode penelitian kepustakaan (library research) pengumpulan data dengan cara dokumentasi. Hasil penelitian berdasarkan tafsiran surat Al Baqarah 256 adalah kekebasan beragama ada dalam Islam yaitu kebebasan dalam keyakinan atau dalam agama, orang memeluk agama Islam atau agama lain tidak boleh atas dasar paksaan, akan tetapi ulama tafsir tidak menjelaskan kebebasan berganti agama.
Parametric Stability Analysis of a Thin Shell Structure Under Own Weight
Authors:   Lecturer, Department of Structural Engineering, Haramaya Institute of Technology, Haramaya University, Ethiopia, Kebede Tamirat
Published: February 2023

In this study, the internal forces, parametric stability and free vibration of elliptic parabolic shell analysis are performed by theoretical and finite element methods. Geometrical and material linearity is considered in modeling and analysis of the structure. Theoretical analysis is done by shallow shell theory and the finite element analysis is carried out by using DLUBAL RFEM 5.3.1. Theoretical formulas in this study are coded by the MATLAB program. The parameter considered thickness, dimension, radius of curvature, modulus of elasticity and side height of the shell for determining the critical buckling load and thickness for free vibration. The internal forces, displacement, critical buckling load and free vibration analysis of result in the study presented graphically and discussed in detail. The result of the finite element analysis is then compared with the theoretical analysis results.
Comparative Study of Building Response on Adoption of NBC105: 2020 and IS 1893 (Part 1): 2016
Authors:   B.E. Student, Oxford College of Engineering and Management, Gaindakot, Nepal., Adhikari Basanta , Poudel Ashish ,   Assistant Professor, Faculty of Civil Engineering, Oxford College of Engineering and Management, Gaindakot, Nepal
Published: February 2023

Nepal suffered a massive loss of life and property from Gorkha Earthquake in 2015AD. Many building structures were either partially or fully damaged and most affected were classic buildings and monuments which were constructed without any design consideration and didn't pose any resistance during the earthquake. After, a broad study and hazard analysis of earthquakes, the Nepal government concluded that the construction methods needed to be revised. The first building regulation in 1994AD known as NBC: 105: 1994 was drafted after the earthquake in 1988 in the eastern part of Nepal. Moreover IS 1893 (Part 1) and IS 13920 codes are still used widely for earthquake resistance design and detailing. But now the Department of Urban Development and Building Construction (DUDBC) has introduced an updated building code of practice NBC 105: 2020 for earthquake-resistant design. In this paper, an effort is done to analyse and compare the effects on buildings of 2-Storey and 3-Storey under the application of IS and NBC code. Equivalent static analysis was carried out with the help of ETABS v19.1.0 and the parameters like base shear, storey displacement and storey drift under both codes are compared. The analysis result shows that the response of building subjected to NBC: 105: 2020 exhibits higher storey responses compared to IS 1893: 2016. Also, the NBC code demands a higher percentage of reinforcement requirements compared to IS code.
Reabsorción radicular externa inflamatoria resultado no deseado en la reimplantación tardía de una avulsión dental. Reporte de un caso
Authors: Mariño Gina , Fernández Diana
Published: February 2023

La avulsión es el desplazamiento completo de la unidad dentaria (UD) fuera del alveolo, ocasionado por un traumatismo, sobre una estructura de soporte de alta resiliencia, provocando el desgarro de las fibras del ligamento periodontal (LPD), la cual debe ser reimplantada de inmediato, lamentablemente, esto no sucede en la mayoría de los casos. Los factores como; el medio de conservación y transporte, el tiempo transcurrido entre el momento de la avulsión y la reimplantación, el grado de maduración de la raíz, el tratamiento de la superficie radicular, la ferulización, la respuesta inmunológica del paciente y la destreza del operador influyen en el éxito de la reimplantación. Este reporte de caso analiza el manejo del incisivo central superior derecho en un paciente de 8 años de edad que sufrió la avulsión de la UD 11, conservado en agua y reimplantado tardíamente (42 horas). Se presentó una reabsorción radicular externa inflamatoria (RREI) como complicación, debido a mal pronóstico y condiciones previas. Sin embargo, el objetivo es restaurar, al menos temporalmente, la estética y la función manteniendo el contorno, el ancho y la altura del hueso alveolar. El diente se podrá extraer, si es necesario, tras una pronta evaluación interdisciplinaria.
Reviewer Acknowledgements for International Journal of Higher Education, Vol. 12, No. 1, 2023
Authors: Sun Susan
Published: February 2023

Reviewer Acknowledgements for International Journal of Higher Education, Vol. 12, No. 1, 2023
Inventing an Academic Translingual/Transcultural Safe Space for International Graduate Students: Our Personal Journey
Authors: Kwon DaYeon , Schwarzer David
Published: February 2023

This article provides a description and reflection of the development of the foundational course for international graduate students in a public university in the Northeast USA. The course was developed in an attempt to provide support and guidance for practitioners and researchers who work closely with international graduate students through transcultural/translingual and whole-person approaches. Our proposed foundation course better prepares international graduate students for academic success in their first term. Recommendations for creating the first-term foundation course for international graduate students are posed at the end of this article.
Sylvia Plath's The Bell Jar: A Feministic Reading
Authors: Alrasheedi Naeemah
Published: February 2023

At the time when Sylvia Plath was at her most productive artistically, sea changes were underway in America and the entire western world. Following the changed socio-economic dispensation in the aftermath of the intense activity of the Second World War, there was a revival in women’s demands for a better social status and this came to be known as the Second Feministic Movement. As a symptom and result of this, women’s authorship flowered and struggled at the same time, the aim being to present the world view of women for women, a departure from the so-far prevailing world view of men for women. However, to limit the former as ‘feministic’ would perhaps not be a just act. This study, accordingly, undertakes deep textual and sub-textual analysis of Sylvia Plath’s The Bell Jar, long seen as a feminist writer’s artistic expression, to establish how far the feministic thought is intertwined in the narrative.
Validation of the PhenoGlad model and determination of planting dates of the gladiolo for the state of Paraná
Authors: Becker Dislaine , Paulus Dalva , Bosco Leosane Cristina , Hojo Ellen Toews Doll , Sato Alessandro Jefferson , Yamamoto Lilian Yukari , Ritter Giovana , Nava Gilmar Antônio
Published: February 2023

Mathematical models that simulate crop development are important tools to help growers plan management practices and harvest time for cut flowers such as gladiolus. The objective of this work was to validate the PhenoGlad model for the State of Paraná, determining the planting date for marketing flowers for the Day of the Dead, and the quality of the floral stems. The validation of the PhenoGlad model was carried out through field tests in five towns in the State of Paraná, namely: Cascavel, Dois Vizinhos, Marechal Cândido Rondon, Palotina, and Santa Helena. The experiments were carried out during the year 2019. The PhenoGlad model was run for each location and year of meteorological data for the early, The PhenoGlad model was simulated for each location and period of meteorological data available at each weather station in these towns, and for the early, intermediate II, and late development cycles. The planting date was determined through the average of the dates (Julian days) for each simulated year. The variables analyzed were the stages of development according to the phenological scale of the culture, the number of leaves, the average number of florets, and the classification of floral stems according to the quality standards of Veilling Holambra. The PhenoGlad model showed accuracy in simulating the stages of development of gladiolus culture in the state of Paraná and is also suitable for predicting the damage caused by extreme temperatures in floral stems, which was confirmed by the damage caused to sepals and petals of gladiolus in field experiments in the towns of Cascavel, Dois Vizinhos, Palotina, and Santa Helena. The best model performance was observed when simulating the vegetative period of the crop, presenting a low error of 0.54 leaf. In the state of Paraná, for the production of floral stems for the Day of the Dead, the PhenoGlad model simulated the planting dates in the different towns studied from August 1 to August 23. The towns of Cascavel and Marechal Cândido Rondon presented a higher number of florets and higher quality of floral stems than the other towns evaluated.
Complications and Outcomes of Septicemia in Urinary Tract Infection
Authors: Tariq Akram , Asif Hina , Khalid Sidra , Tanvir Imrana
Published: February 2023

Urinary tract infection (UTI) is a common bacterial infection that can progress to septicemia, a serious and potentially life-threatening condition. Septicemia occurs when bacteria from an infection in one part of the body spread to the bloodstream and cause a systemic inflammatory response. Early recognition and treatment of septicemia in UTI is crucial to prevent serious complications and improve outcomes. Objective: To explore the complications and outcomes of septicemia in UTI. Methods: The cross-sectional, descriptive, and observational. 101 patients with septicemia due to UTI were enrolled from the medical wards and Accident and Emergency Department of Mayo Hospital Lahore. Liver function tests, renal function tests, and full blood counts were performed on each patient. Data were entered into a Performa created for this study, and the latest SPSS version was used for data analysis. Results: Majority of males and females had normal bilirubin and Na+ and K+ levels. WBCs were high in 13/16 males and14/16 females. Platelets were low in 9/16 males but normal in 9/16 females. Hemoglobin. Conclusions: Septicemia in UTI is a serious and potentially life-threatening complication. Early recognition and treatment of septicemia is crucial to prevent serious complications and improve outcomes
Phenotypic and molecular characterization of vibrio species isolated from cultured marine Dicentrarchus labrax
Authors: Mamdouh Nelly , Khalil Samy , Naggar Mahmoud , A Fadel
Published: February 2023

Vibrio species are the most common and serious pathogens in fish and shellfish marine aquaculture worldwide with high mortalities and morbidity, lead to great economic loss. Among all V. species infecting V.parahaemolyticus and V. alginolyticus taken the first place.The present study aimed to determine the prevalence of Vibrio species in seabass in addition detection of certain virulence genes. A total of 220 seabass seabass (Dicentrarchus labrax) had haemorrhage, erosion and ulcers in the skin ,gills,fin base and tail and were purchased from fish markets at from Alexandria, Behaira, lake Qarun and subjected to phenotypic bacteriological examination. revealed that the prevalence of 4 vibrio isolates was 1.8% (4/220) including two isolates of V. alginolyticus (one from liver and other from spleen) and two isolates of V. parahaemolyticus (one from liver and other from kidney). Molecular identification based on use of 16srRNA gene sequence confirmed 4 strains as vibrio species. Proving its pathogenicity through using primers for the virulence genes (trh, tlh, recA and categorized 2 isolates belong to vibrio alginolyticus (one with trh) and 2 isolates belong to vibrio parahaemolyticus (one with recA and tlh, the other with trh). The 4 strains of V. parahaemolyticus and V. alginolyticus were multi drug resistant (MDR),resist more than 3classes of antibiotics, which pose potential health hazards to consumers
Diseases problems in cluttered sea bass Dicentrarchus Labrax reared in cages from Fingerlings until marketing size in Mariout Valley at King Mariout in Alexandria province
Authors: Roshdy Mahmoud , khalil Ryad , latif Hani , Saad Talaat , Tanekhy Mahmoud
Published: February 2023

This study aimed to determine and identify the common bacterial infection in different stages of cultured sea bass during the different season. In addition Eexperimentally infected the sea bass with the Vibrio alginolyticus and Vibrio parahemolyticus. The aquarium trial was carried out with European seabass (Dicentrarchus labrax) in private fish farm at Borg El-Arab, Alexandria governorate Egypt. At total 50 of seabass was used during the study. The study lasted 10 weeks, starting with 50 ± 5 gram /fish. Prior to the start of the trial, the fish were fed with a commercial diet (45 percent CP, crude protein). Water quality parameters were monitored during fish acclimatization and throughout the trial. Water temperature, pH and dissolved oxygen remained within acceptable ranges for marine production during the trial. Our study concluded that, Vibrio alginolyticus and Vibrio parahemolyticus causes a great losses in cluttered sea bass Dicentrarchus Labrax reared in cages The presence of histopathological lesions in the internal organs clearly explained the septicemic nature of Vibrio infection. Altogether, the full confirmation of Vibrio infection ought to incorporate, examination of fishes for the visible clinical signs, postmortem examination, isolation of the causative agent using specific media and biochemical tests, and histopathological examination of the internal organs as a proof of septicemic nature of the Vibrio infection. The sensitivity test revealed sensitive to ciprofloxacin (Cipro 5μg), novobiocine (NV 30 μg), intermediate sensitivity was found to Oxytetracycline (OT 30 μg) while, the resistance was observed to amoxicillin (Aml 10 μg) and colisitine sulphate (CT 10 μg)
Phenotypic and Genotypic Characterization of Klebsiella pneumoniae isolated from Clinical Mastitis in Buffaloes
Authors: Mousa Walid , Abdelkhalek Hanaa , Nagib Hanan , Elias Randa , Mansour Saad
Published: February 2023

Mastitis is the most common serious and economical disease affecting the dairy industry. The current study aimed to determine the molecular characterization of K. pneumoniae isolated from buffaloes with clinical mastitis as well as determine the antimicrobial pattern and virulence associated genes. Out of examination one hundred and fifty dairy buffaloes at Beheria governorate, 57 (38%) showed clinical mastitis signs. All samples are submitted to bacteriological examination and confirmed by biochemical tests. The result showed that K.pneumoniae was identified in only five (8.7%). Regarding to the antibiogram profile, K. pneumoniae isolates exhibited high resistance pattern against Carbenicillin, Cefotaxime, Flumequine, Gentamicin, Kanamycin (100%) followed by Neomycin, Nitrofurantoin, Penicillin (80%) and Oxytetracycline, Sulfamethoxazole / trimethoprim (60%). Meanwhile, higher susceptibility to Ampicillin (100%), followed by Chloramphenicol, Colistin Sulphate, Erythromycin, and Streptomycin (80%). Molecular identification using the mPCR approach applied efficiently to detect the K. pneumoniae virulence genes (mrkA, mrkD, iutA) at 475, 226, 300bp respectively. In addition, the successfully detection of blaTEM and blaSHV for β lactams resistance genes at 516 and 392 bp. In conclusion, the phenotypic and genotypic resistance pattern of K. pneumoniae isolates indicates the portability of transmission of resistance genes through milk and food chain with public health concern.
Evaluation of patients applying for disability determination procedures in terms of spine injury
Authors: Dalgic Sertac , Cetin Selcuk
Published: February 2023

Vertebral are not easily injured due to both the strength of the bone structure and the anatomical protection of the soft tissues. Traumas that cause damage to the vertebral column are often high-energy traumas such as traffic accidents. In our study, vertebral fractures seen in patients who applied for a report for disability determination; were aimed to evaluate the fracture site in terms of its sequelae and its provisions in the disability determination charts. In our study, the reports of the cases that were examined by us after applying for disability assessment in Tokat Gaziosmanpaşa University Faculty of Medicine, Department of Forensic Medicine between the years 2019-2021 were examined. Cases with vertebral injuries were included in the study and were examined in terms of age, gender, spine region, additional traumatic findings, sequelae, treatment method, how many points they got from which disability scale, and duration of incapacity. As a result of joint range of motion examinations, in cervical vertebral fractures, limitation of cervical extension movement, in thoracic vertebral fractures, limitation of thoracic flexion movement, in lumbar vertebral fractures, it was determined that the limitation of lumbar extension movement was observed mostly. In our study, vertebral injuries were seen in 17% of the patients who applied for disability detection procedures after a traffic accident. In addition, vertebral injuries are important injuries in terms of public health and health expenditures, as well as important causes of disability and incapacity to work. Vertebral injuries resulting from traffic accidents can cause significant limitations and adversely affect people's lives.
Evaluation of the findings affecting the treatment decision in cases of adhesive intestinal obstruction
Authors: Isler Ali , Bozan Mehmet , Sanli Ahmet , Yasar Fatih
Published: February 2023

To establish a standard approach in patient management by determining the parameters that affect the decision of surgical or conservative treatment in adhesive small bowel obstructions. 94 patients who were admitted to the emergency department with symptoms of ileus and were diagnosed with adhesive intestinal obstruction according to clinical, examination and imaging findings were grouped as patients who were followed up with conservative methods (Group 1) and patients who underwent surgery (Group 2). All patients' laboratory values (hemoglobin, white blood cell (WBC), C- reactive protein (CRP), Blodd urea nitrogen (BUN)/creatinin, sodium, potassium, Lactate dehydrogenase (LDH), lactate and amylase) and imaging findings (air-fluid level in direct abdominal X-ray, increase in small intestine diameter (≥3.95 cm) in computerized tomography), wall thickness increase (>3mm), transition zone, fecal sign, and presence of contrast in the colon) were evaluated, and criteria for early surgery and non-operative follow-up-treatment criteria were determined. 72% (n:68) of the patients were classified as Group 1 and 28% (n:26) as Group 2, and no significant difference was found between the groups according to age and gender. Surgical treatment with increased lactate (r:0.326, p=0.001), diameter increase in the small intestine (r:0.299, p=0.003) and wall thickness increase (r:0.540, p<0.001), change in air-fluid levels on direct X-ray ( A significant correlation was found between r:-0.291, p=0.004) and contrast transfer to the colon on tomography (r:-0.668, p<0.001) and the decision for conservative treatment. Although adhesive intestinal obstruction is a condition that can mostly be managed non-operatively, the early surgical decision significantly reduces mortality and morbidity in cases with an operation indication. It was concluded that the standard approach protocol based on laboratory and imaging findings determined in the non-operative or operative treatment management helps in the differential diagnosis and early surgical decision and reduces the length of stay of the patient.
A study of A2B subgroup frequency among AB blood group in our tertiary care center
Authors: Mori Neelaba , Algotar Chandrika , Ghelani Siddharth , Patel Maitri
Published: February 2023

Background: The ABO blood group system invented by Karl Landstiner is popular blood grouping system and considered as the most vitalin blood transfusion safety. Approximately, 20% of individuals having A2 subgroup and 80% have A1 subgroup.

Aims and Objectives: The objective of the present study is to find the prevalence of A1B and A2B subgroups in samples of patients in blood center of our tertiary care center.

Materials and Methods: This observational study was carried out at blood center of tertiary care hospital. Blood group is separated into A, B, AB, and O-positive/negative. Based on serological reactivity, blood group was classified into A2B positive/A2B negative.

Results: ABO blood grouping was analyzed for 5435 samples. Of these, 430 (7.91%) belonged to Group AB. Out of 430 AB group, 13 (3.1%) were having A2B-positive blood group and 417 (96.9%) were having A1B-positive blood group.

Conclusion: Among AB blood group, frequency of A1B subgroup is higher than A2B. The study of this subgrouping can make blood transfusion more safe and can improve overall practice of transfusion.
Bacteriological profile and antibiotic susceptibility of blood culture from neonates in GMERS Medical College, Gandhinagar
Authors: Chauhan Hardik , Khokhar Neeta , Patel Parul , Shrimali Gaurishanker , Makwana Neha
Published: February 2023

Background: Neonatal sepsis refers to an infection involving bloodstream in newborn infants <28 days old. Neonatal sepsis contributes substantially to neonatal morbidity and mortality and is an ongoing major global public health challenge.

Aim and Objectives: The objectives of this study were to study bacteriological profile and antibiotic susceptibility of blood culture from neonates in GMERS Medical College, Gandhinagar.

Materials and Methods: For culture and antimicrobial susceptibility test, blood samples were taken from the suspected cases admitted in NICU. Total 271 blood culture positive NICU admitted patient with septicemia were taken in this study.

Results: Total 271 septicemic neonates having blood culture positive septicemia, neonatal septicemia was predominantly caused by Gram-negative organism Klebsiella pneumonia (40.60%). Among the all Gram-negative organisms, Piperacillin/Tazobactam was most sensitive drug followed by Meropenem. Moreover, for the all Gram-positive organism, vancomycin and linezolid were the most sensitive drugs.

Conclusion: Neonatal septicemia is major cause of morbidity and mortality in India. Multiple antibiotic resistance among the isolates worsen the condition more. A high level of suspicions is needed on clinical ground for diagnosis. Judicious use of antibiotics should be promoted.
Detection and correlation of antimicrobial resistance pattern in Enterobacteriaceae from UTI patients in GMERS Medical College, Gujarat
Authors: Jadeja Bindu , Khokhar Neeta , Patel Parul , Shrimali Gaurishanker , Makwana Neha
Published: February 2023

Background: Bacterial resistance to antibiotics is a growing public health threat worldwide. The increasing rate of antimicrobial resistance among bacterial pathogens causing both hospital- and community-acquired infections is a serious threat to public health world-wide. This inappropriate and non-judicious usage of antibiotics has resulted in the development of worldwide antibiotic resistance in bacteria, leading to the emergence of multi-resistant strains of bacterial pathogens. This study focuses on the prevalence of antibiotic resistance in the Enterobacteriaceae group of organisms in urine samples and also detects various methods of antibiotic resistance. Antibiotic resistance detection may be useful for epidemiological and research purposes, as well as for preventing the spread of drug-resistant organisms within hospitals through good infection control practices.

Aims and Objectives: The aim of the study was to detect occurrence of β-lactamases, extended-spectrum beta-lactamases (ESBL) and Carbapenemase by phenotypic methods in Enterobacteriaceae from urine samples along with pattern of antibiotic resistance for various antibiotics in them.

Materials and Methods: A descriptive study was conducted at a tertiary-care hospital. Testing of ESBL and carbapenemase production detection done according to CLSI (M100) guideline by the Kirby-Bauer disk diffusion method, combination disc diffusion test, and modified Carbapenem inactivation method.

Results: A total of 220 Enterobacteriaceae organisms were isolated from processed urine samples of tertiary care Hospitals. Rate of cephalosporin resistance in ESBL and carbapenem-resistant Enterobacteriaceae (CRE) is more than 90% while in non-ESBL more than 70% and in non-CRE 75–80%. Carbapenem resistance in ESBL and non-ESBL is the same. Resistance to fluoroquinolone group, Aminoglycoside group, and Cotrimoxazole and Tetracycline group of antibiotics were more noticed in ESBL and carbapenemase producing organisms. In our study, fosfomycin and Nitrofurantoin are effective treatment in case of ESBL and CRE producing organism.

Conclusion: The ESBL and Carbapenemase producing isolates were multi-drug resistant making therapeutic choices limited. Fosfomycin and Nitrofurantoin are effective treatment in multidrug resistance urinary tract infection.
Echocardiographic diagnosis of aorto-left ventricular tunnel with supravalvular pulmonic stenosis in a Shih-tzu dog
Authors: Noh Daji , Shin Hyunguk , Choi Sooyoung , Choi Hojung , Lee Youngwon , Lee Kija
Published: February 2023

Background: The aorto-left ventricular tunnel (ALVT) is a congenital extracardiac channel that connects the ascending aorta to the left ventricle.
Case Description: A 2-year-old Shih-tzu dog presented with mild exercise intolerance. Echocardiography revealed an abnormal slit-like tunnel structure connecting the ascending aorta to the left ventricle, with diastolic blood flow from the aorta to the left ventricle. Echogenic membranous stenosis was observed in the main pulmonary artery. Based on these findings, the dog was diagnosed with ALVT and type I supravalvular pulmonic stenosis.
Conclusion: This is the first case report of ALVT in veterinary medicine that describes diagnostic imaging findings. ALVT should be considered in dogs with an aortic regurgitation murmur and can be detected by echocardiography.
TROMBOSE VENOSA CEREBRAL SECUNDÁRIA A MUTAÇÃO DO FATOR V DE LEIDEN: UM RELATO DE CASO
Authors: Veiga Ana Carolina Coutinho , Bicalho Rafaela Leite , Da Cunha Isabela Miranda , De Souza Antonnielle Ronney Fernandes , Leal Bárbara Pereira Pires
Published: February 2023

A trombose venosa cerebral, condição rara muitas vezes subdiagnosticada, se apresenta com um amplo espectro de sinais e com alta variabilidade do modo de início. Sua ocorrência é três vezes maior no sexo feminino. Os autores têm como objetivo relatar um caso de uma paciente com diagnóstico de trombose venosa cerebral. Este diagnóstico, por vezes, é muito difícil devido ao amplo espectro de sintomas e às múltiplas etiologias, e pode ser confirmado por exames de neuroimagem. Os principais fatores de risco para TVC em adultos são as condições pró-trombóticas, genéticas ou adquiridas e o uso de contraceptivos orais. Mutações genéticas têm sido associadas a trombose de seio, sendo a principal delas a mutação do Fator V de Leiden. Durante a investigação, além do uso de anticoncepcional pela paciente, o teste genético revelou heterozigose do Fator V de Leiden. O tratamento é baseado na combinação de heparina intravenosa, seguida por anticoagulação oral por toda vida devido ao risco de trombose recorrente.
Comparison of Physical Activity, Depression and Quality of Life in Geriatric Population Living in Old Age Home and Community
Authors:   Krupanidhi College of Physiotherapy, Bangalore, Karnataka, India, Mehulbhai Bhatt Pranali , Sandeep Sheth Megha
Published: February 2023

To find the comparison between physical activity, depression and quality of life in elderly living in old age homes and communities. A cross-sectional survey study of 300 participants fulfilling the inclusion and exclusion criteria by convenience sampling was conducted in geriatric population from age 65-85 years. Comparison of physical activity, depression and quality of life was done in geriatric population. Inclusion Criteria: -Males and Females, 65-85 years of age. Exclusion Criteria: -Subjects having any neurological conditions, severe orthopedic conditions, vision hearing loss, severe respiratory disorders and suffering from terminal disease and dementia. Mean GDS score for Group A was 5.68±3.6 and Group B was 2.88±1.41. Difference in mean GDS between the groups was 4.28±3.63 (U=5.982, p<0.001). Mean IPAQE score for Group A was 1905±2604 MET and Group B was 2552±2145 MET. Difference in mean IPAQE between the groups was 2229±2459 MET (U=8.724, p<0.001). Mean OPQOL for Group A was 126.6±15.5 and Group B was 142.9±13.4. Difference in mean OPQOL between the groups was 16.3±2.1 (U=5.322, p<0.001). The present study concluded that geriatric population living in old age homes is more depressed and has low level of physical activity than elderly living in community. This shows that elderly living in community have better quality of life than elderly living in old age homes Keywords Geriatric population, Physical Activity, Depression and Quality of life
Classifications of developing a strategy for the development of a higher education institution
Authors: Temirov Ortiq
Published: February 2023

The article examines existing approaches to the classification of development strategies of higher education institutions, analyzes the possibilities, conditions and limitations of their application to higher education organizations. Also, internal (characteristics of the higher education institution) and external (characteristics of the environment in which the higher education institution operates) factors are described in choosing the strategy of the higher education institution.
Foreign experience of personal income tax forecasting
Authors: Khudoykulov Sadirdin , Babaev Shavkat
Published: February 2023

This article reflects the problems of foreign experience in forecasting tax revenues from personal income tax and a methodological approach to further improvement of this process.
Forecasting macroeconomic indicators at the stage of transition to inflation targeting policy in Uzbekistan
Authors: Bahriddinov Vigorjon
Published: February 2023

In this paper, forecasted the main macroeconomic indicators, such as inflation, economic growth, nominal wages, money supply and exchange rate in the context of the transition to inflation targeting policy in Uzbekistan. The medium-term forecasting covers the periods from Q1 2022 to Q4 2024 using AR, VAR, ARIMA and DF models. Also, the accuracy of the forecasting model results checked by MSE, MAE and MAPE methods. Furthermore, developed conclusions and suggestions based on forecast results.