Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Authors: Wyckoff Myra H. , Wyllie Jonathan , Aziz Khalid , de Almeida Maria Fernanda , Fabres Jorge , Fawke Joe , Guinsburg Ruth , Hosono Shigeharu , Isayama Tetsuya , Kapadia Vishal S. , Kim Han-Suk , Liley Helen G. , McKinlay Christopher J.D. , Mildenhall Lindsay , Perlman Jeffrey M. , Rabi Yacov , Roehr Charles C. , Schmölzer Georg M. , Szyld Edgardo , Trevisanuto Daniele , Velaphi Sithembiso , Weiner Gary M. , Davis Peter G. , Dawson Jennifer , Ersdal Hege , Foglia Elizabeth E. , Kawakami Mandira , Lee Henry C. , Rüdiger Mario , Sawyer Taylor , Soraisham Amuchou , Strand Marya , Udaeta Enrique , Urlesberger Berndt , Yamada Nicole K. , Madar John , Escobedo Marilyn B. , Ganguly Abhrajit , Gately Callum , Kamath-Rayne Beena , Mausling Richard , Domingo-Bates Jocelyn , Nakwa Firdose , Ramachandran Shalini , Ring Jenny , Shah Birju , Stave Christopher , Tamura Masanori , te Pas Arjan , Cheng Catherine , El-Naggar Walid , Finan Emer , Fuerch Janene , Halamek Lou , Kamlin Omar , Lakshminrusimha Satyan , McGowan Jane , Niermeyer Susan , Quek Bin Huey , Singhal Nalini , Testoni Daniela 
Published: October 2020

This
2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
(CoSTR) for neonatal life support includes evidence from 7 systematic reviews, 3 scoping reviews, and 12 evidence updates. The Neonatal Life Support Task Force generally determined by consensus the type of evidence evaluation to perform; the topics for the evidence updates followed consultation with International Liaison Committee on Resuscitation member resuscitation councils. The 2020 CoSTRs for neonatal life support are published either as new statements or, if appropriate, reiterations of existing statements when the task force found they remained valid.

Evidence review topics of particular interest include the use of suction in the presence of both clear and meconium-stained amniotic fluid, sustained inflations for initiation of positive-pressure ventilation, initial oxygen concentrations for initiation of resuscitation in both preterm and term infants, use of epinephrine (adrenaline) when ventilation and compressions fail to stabilize the newborn infant, appropriate routes of drug delivery during resuscitation, and consideration of when it is appropriate to redirect resuscitation efforts after significant efforts have failed.

All sections of the Neonatal Resuscitation Algorithm are addressed, from preparation through to postresuscitation care. This document now forms the basis for ongoing evidence evaluation and reevaluation, which will be triggered as further evidence is published.

Over 140 million babies are born annually worldwide (
https://ourworldindata.org/grapher/births-and-deaths-projected-to-2100
). If up to 5% receive positive-pressure ventilation, this evidence evaluation is relevant to more than 7 million newborn infants every year. However, in terms of early care of the newborn infant, some of the topics addressed are relevant to every single baby born.