bluuebunny/crossref_metadata_2025 huggingface dataset:
Paving the way for new and challenging matrix reference materials—particle suspensions at the core of material processing providing RMs for method development and method validation
Authors: Emteborg Håkan , Seghers John , García-Ruiz Silvia , Elordui-Zapatarietxe Saioa , Breidbach Andreas , Labibes Kamel , Charoud-Got Jean , Koeber Robert
Published: November 2023

Sufficient homogeneity of the certified parameter(s) over the whole fill series of a matrix reference material (RM) is a fundamental quality criterion. In practice, the heterogeneity of the target parameter is evaluated, whereby a relative value can be calculated of how much the target parameter is varying over the RM-batch. A high degree of homogeneity (low heterogeneity) is an inherent quality mark of a good RM. Here, we report how challenging matrix RMs were produced by using particle suspensions at the core of the material processing step. The examples of matrix RMs produced span from whole water reference materials for persistent organic pollutants, PM2.5-like atmospheric dust certified for specific ions to microplastic RMs. Most of these RMs were subsequently used in different phases of analytical method development or for method validation. Common to all these matrices is that they cannot be easily mixed, handled, or dosed to prepare larger sample batches. In all cases, a continuously stirred suspension of particles was used during material processing. In general, relative between-bottle heterogeneities from 1.6 to 6% were achieved for the target parameters in these matrix presentations. Concerning developments of new CRMs in emerging fields, the co-dependence between the availability of validated analytical methods with good repeatability and testing materials with a known and high homogeneity of the target parameter(s) becomes particularly challenging. This situation is an RM/Method causality dilemma. To overcome that hurdle, strategies are proposed for stepwise processes where RM producers and a network of analytical method developers could work hand in hand. In addition, development of a portfolio of inexpensive and well-homogenised common samples coupled with a reporting interface is suggested. This would benefit method developers and RM producers alike. As more and more data is compiled for a specific matrix, it paves the way for new and challenging RMs that can later be used by a wider community.
National digital pathology projects in Switzerland: A 2023 update
Authors: Grobholz Rainer , Janowczyk Andrew , Frei Ana Leni , Kreutzfeldt Mario , Koelzer Viktor H. , Zlobec Inti
Published: November 2023

The Swiss Digital Pathology Consortium (SDiPath) was founded in 2018 as a working group of the Swiss Society for Pathology with the aim of networking, training, and promoting digital pathology (DP) at a national level. Since then, two national surveys have been carried out on the level of knowledge, dissemination, use, and needs in DP, which have resulted in clear fields of action. In addition to organizing symposia and workshops, national guidelines were drawn up and an initiative for a national DP platform actively codesigned. With the growing use of digital image processing and artificial intelligence tools, continuous monitoring, evaluation, and exchange of experiences will be pursued, along with best practices.
Association of central blood pressure with an exaggerated blood pressure response to exercise among elite athletes
Authors: Most Astrid , Kraushaar Lutz , Dörr Oliver , Keranov Stanislav , Hoelscher Sophie , Weber Rebecca , Akdogan Ebru , Groesser Vincent , Husain-Syed Faeq , Nef Holger , Hamm Christian W. , Bauer Pascal
Published: November 2023

Purpose

The systolic blood pressure/workload (SBP/MET) slope was recently reported to be a reliable parameter to identify an exaggerated blood pressure response (eBPR) in the normal population and in athletes. However, it is unclear whether an eBPR correlates with central blood pressure (CBP) and vascular function in elite athletes.

Methods

We examined 618 healthy male elite athletes (age 25.8 ± 5.1 years) of mixed sports with a standardized maximum exercise test. CBP and vascular function were measured non-invasively with a validated oscillometric device. The SBP/MET slope was calculated and the threshold for an eBPR was set at > 6.2 mmHg/MET. Two groups were defined according to ≤ 6.2 and > 6.2 mmHg/MET, and associations of CBP and vascular function with the SBP/MET slope were compared for each group.

Results

Athletes with an eBPR (n = 180, 29%) displayed a significantly higher systolic CBP (102.9 ± 7.5 vs. 100 ± 7.7 mmHg, p = 0.001) but a lower absolute (295 ± 58 vs. 384 ± 68 W, p < 0.001) and relative workload (3.14 ± 0.54 vs. 4.27 ± 1.1 W/kg, p < 0.001) compared with athletes with a normal SBP/MET slope (n = 438, 71%). Systolic CBP was positively associated with the SBP/MET slope (r = 0.243, p < 0.001). In multiple logistic regression analyses, systolic CBP (odds ratio [OR] 1.099, 95% confidence interval [CI] 1.045–1.155, p < 0.001) and left atrial volume index (LAVI) (OR 1.282, CI 1.095–1.501, p = 0.002) were independent predictors of an eBPR.

Conclusion

Systolic CBP and LAVI were independent predictors of an eBPR. An eBPR was further associated with a lower performance level, highlighting the influence of vascular function on the BPR and performance of male elite athletes.
Extracellular nitric oxide sustains root surface redox activity and growth under sudden flooding-induced hypoxic conditions in barley root tips
Authors: Zelinová Veronika , Demecsová Loriana , Liptáková Ľubica , Valentovičová Katarína , Tamás Ladislav
Published: November 2023

Main conclusion

Nitric oxide sustains root tip surface redox activity and restricts lipid peroxidation-triggered cell death in the root tips.

In order to gain more insight into the involvement of nitric oxide (NO) in plant response to sudden flooding-induced hypoxic stress, we studied the effect of two NO donors, sodium nitroprusside and S-nitroso-L-glutathione, on short-term partial submergence-induced root growth inhibition, alteration in root surface redox activity, lipid peroxidation and cell death in two barley cultivars (cv.) at their early seedling stage. The short-term hypoxic stress induces root growth arrest in cv. Karmel, accompanied by increased lipid peroxidation and cell death. By contrast, in cv. Slaven, short-term hypoxic conditions cause only reduced root growth rate, associated with elevated extracellular NO level in the root tips. The root tip surface redox activity decreases with the increasing timespan of hypoxic conditions in both cultivars; however, this decrease in redox activity started earlier and was greater in the cv. Karmel in comparison with cv. Slaven. Application of NO donors during hypoxic stress sustains the root redox activity and eliminates the hypoxia-induced lipid peroxidation, accompanied by a partial restoration of root growth after short-term hypoxic stress. These results suggest that extracellular NO plays a key role in maintaining the root tip surface redox activity and in the restriction of lipid peroxidation and cell death under short-term hypoxic stress in the root tips of barley seedlings.
Influence of confining pressure on permeability and structural properties of selected sedimentary, igneous, and metamorphic rocks
Authors: Kudasik Mateusz , Anioł Łukasz , Gajda Aleksandra , Pajdak Anna
Published: November 2023

As part of the work, studies of the rock’s permeability to gases were carried out using the original measuring apparatus, which makes it possible to study gas seepage through a porous medium under confining pressure conditions corresponding to in situ. Samples of selected sandstone, sapropelic coal, marble, granite, limestone, and spongiolite rocks were used for permeability studies. The permeability of these rocks was determined in relation to helium (He) and carbon dioxide (CO2) in various values of the confining pressure: 1, 5, 10, 15, and 30 MPa. The obtained variability ranges of permeability coefficients allowed to assign the tested samples to particular classes, from poor and tight permeable rocks, where k∞ < 1 mD and k∞ < 0.1 mD (granite, marble), through good permeable rocks with a value of 10 < k∞ < 100 mD (limestone, spongiolite, sandstone), to very good permeable rocks with coefficient k∞ > 100 mD (coal). The Klinkenberg slippage effect was twice as large for He compared to CO2, and as permeability increased, the slippage effect disappeared. The Walsh model was used to analyze the obtained results, based on which it was found that the highest impact of effective stress was observed for a granite sample, the smallest for sapropelic coal, where an increase in effective stress by about 30 MPa reduced the permeability of coal to He by 50% and to CO2 by 30%. Changes in the structural properties of rocks as a result of subjecting them to gas seepage processes under confining pressure conditions were also examined. Open porosity, specific surface area, pore size distribution, and mean pore diameter in the samples were determined. In most of the studied rocks, a decrease in porosity and a reduction in the pore space of the rocks were observed after permeability tests under confining pressure conditions.
An Amundsen Sea source of decadal temperature changes on the Antarctic continental shelf
Authors: Drijfhout Sybren S. , Bull Christopher Y. S. , Hewitt Helene , Holland Paul R. , Jenkins Adrian , Mathiot Pierre , Garabato Alberto Naveira
Published: November 2023

Mass loss from the Antarctic Ice Sheet is dominated by basal melting–induced warm ocean water. Ice-sheet mass loss and thinning of buttressing ice shelves occur primarily in the Amundsen and Bellingshausen Seas. Here, we show that in a global ocean simulation using the 0.25° Nucleus for European Modeling of Ocean (NEMO) model driven by the JRA55 reanalysis from 1982 to 2017, the Amundsen sector of the Antarctic continental shelf acts as a gateway, regulating the on-shelf access of warm Circumpolar Deep Water (CDW) from the deep ocean and its westward transfer to other sectors up to ca. 90° E, particularly the Ross Sea. As a result, anomalies in Antarctic-shelf-averaged temperature mainly originate in the Amundsen sector. These changes are primarily governed by shifts in the Amundsen Sea Low associated with tropical climate variability, modulating the on-shelf transport of CDW via wind-driven perturbations to ocean currents. The ensuing temperature anomalies progress westward from the Amundsen Sea via three distinct routes: a slow, convoluted westward pathway on the shelf via the Antarctic Coastal Current; a faster westward pathway along the shelf break via the Antarctic Slope Current and then onto the shelf along topographic troughs; and a third, eastward route toward the Bellingshausen sector, whereby temperature anomalies are transported into a region of local wind-generated changes farther north. These results emphasize the importance of the Amundsen sector for climate variability over the Antarctic shelves.
On adsorption azeotropy and a classification based on the dual site Langmuir isotherm
Authors: Brandani Stefano
Published: November 2023

Adsorption azeotropy is a phenomenon that has been known for nearly a century, yet few properties have been formally proven. Here four general properties of adsorption azeotropy in porous materials are discussed and shown to apply irrespective of the isotherm, including the fact that there is always a lower bound on the pressure at which an azeotrope may be present. As molecules of different size will favour the occurrence of an azeotrope, this study considers in detail the thermodynamically consistent dual site Langmuir model, where azeotropy is solely the result of the adsorbent heterogeneity. Six categories of adsorption azeotropes, which can be grouped into three pairs of mirror cases, are formally identified for this model. Dimensionless ratios allow to determine formally each category and the analysis also includes a discussion of the crossing of the pure component isotherms. The heterogeneity of the adsorbent is shown to lead to azeotropes that can include an upper bound on pressure; that can occur even if the pure component isotherms do not cross; and can be present below the pressure at which the pure component isotherms cross. Finally, the analysis allows to identify also the ranges of parameters for which the pure component isotherms cross but an azeotrope is not present.
Effect of a microbial phytase on the growth performance, digestibility and retention in a high plant meal inclusion diet for Atlantic salmon (Salmo salar)
Authors: Terrey David Edward , Braidi Daniel Arana , Serwata Robert
Published: November 2023

The effect of supplementation of a novel phytase (OptiPhos®; Huvepharma; 750 OTU) to high plant meal inclusion diets for Atlantic salmon (Salmo salar) was assessed. Diets were prepared without phytase, with phytase and with supplemental inorganic phosphorus (MCP). After 61 days significant increases in growth, FCR and protein efficiency were seen in diets supplemented with phytase and with MCP over the negative control (P < 0.05). Addition of phytase significantly increased digestibility of phytate and phosphorus (P) as well as retention over other diets (P < 0.05). Phytase addition significantly decreased faecal P losses while increasing metabolic loss over the negative control (P < 0.05). Addition of MCP showed significant increases in metabolic P loss (P < 0.05). In conclusion, the addition of phytase (OptiPhos®; Huvepharma) resulted in performance improvements comparable to inorganic P dosing, while significantly improving the reduction of effluent wastes from plant meal-based diets.
Seismic risk assessment of residential buildings by the Heuristic vulnerability model: influence of fragility curve models and inventory scale
Authors: Colajanni Piero , D’Anna Jennifer
Published: November 2023

Typological-observational methods still constitute one of the most commonly applied tools for evaluation of the seismic risk and vulnerability of the existing building stock. Their efficiency is mainly related to the effectiveness of the procedure for deriving fragility curves, and the reliability and completeness of the database that describes the building stock. This paper presents a comparison between the vulnerability and damage distribution assessment provided by fragility curves used in the Macroseismic and Heuristic methods, and a comparison of exposure evaluation methodologies according to two different approaches, namely a compartment- and a building-scale survey. An application to the case study of the residential building stock in the historic center of Alcamo, a town of 45,000 inhabitants in Western Sicily (Italy), shows the major reduction in fragility provided by recalibration of the masonry buildings’ ductility values that characterize the Heuristic method. Moreover, the efficiency of the compartment scale survey approach, based on the CARTIS typological-structural characterization method of ordinary buildings in urban areas, is underlined.
Fast satellite DNA evolution in Nothobranchius annual killifishes
Authors: Voleníková Anna , Lukšíková Karolína , Mora Pablo , Pavlica Tomáš , Altmanová Marie , Štundlová Jana , Pelikánová Šárka , Simanovsky Sergey A. , Jankásek Marek , Reichard Martin , Nguyen Petr , Sember Alexandr
Published: November 2023

Satellite DNA (satDNA) is a rapidly evolving class of tandem repeats, with some monomers being involved in centromere organization and function. To identify repeats associated with (peri)centromeric regions, we investigated satDNA across Southern and Coastal clades of African annual killifishes of the genus Nothobranchius. Molecular cytogenetic and bioinformatic analyses revealed that two previously identified satellites, designated here as NkadSat01-77 and NfurSat01-348, are associated with (peri)centromeres only in one lineage of the Southern clade. NfurSat01-348 was, however, additionally detected outside centromeres in three members of the Coastal clade. We also identified a novel satDNA, NrubSat01-48, associated with (peri)centromeres in N. foerschi, N. guentheri, and N. rubripinnis. Our findings revealed fast turnover of satDNA associated with (peri)centromeres and different trends in their evolution in two clades of the genus Nothobranchius.
Investing in Your Alumni: Endowments’ Investment Choices in Private Equity
Authors: Füss Roland , Morkoetter Stefan , Oliveira Maria
Published: November 2023

We investigate the role of alumni ties in university endowments’ decision to invest into private equity funds. Based on a sample of 1,590 commitments made by 189 U.S. endowments into 613 funds during the period of 1995 to 2017, we show that endowments are more likely to invest into funds that are managed by the alumni of their own alma mater. This finding is more pronounced for less prestigious and less private equity experienced university endowments. Thus, our results are not only dominated by institutions with a larger proportion of active alumni in the private equity industry. Furthermore, we observe that alumni ties are not associated with better performance compared to other endowment investments where such a tie does not exist.
Combined effects of water salinity and ammonia exposure on the antioxidative status, serum biochemistry, and immunity of Nile tilapia (Oreochromis niloticus)
Authors: Dawood Mahmoud A. O. , Gewaily Mahmoud , Sewilam Hani
Published: November 2023

Growing Nile tilapia in brackish water showed promising results, but the possibility of ammonia exposure can interrupt health status and productivity. Herein, the study tested the combined effects of water salinity and ammonia exposure on the antioxidative status, serum biochemistry, and immunity of Nile tilapia. Fish were assigned to eight groups where fish were reared in saline water (5, 10, and 15 ppt) with continuous or intermittent (every 3 days) total ammonia (TAN) exposure (5 mg TAN/L) (2 × 4 factorial design). After 30 days, the water salinity, TAN, and their interaction were markedly (P < 0.05), affecting the growth performance (final weight, weight gain, and specific growth rate) and survival rate of Nile tilapia. The growth performance and survival rate were markedly lower in tilapia grown in 15 ppt with continuous TAN exposure than in the remaining groups. The results showed that fish exposed to higher salinity levels (10 and 15 ppt) and continuous TAN exposure had a more robust antioxidative response, as evidenced by higher superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) activities and lower malondialdehyde (MDA) levels in the homogenates of the gills, intestines, and livers. The gills were notably affected, with congestion of primary filaments blood vessels and degeneration or shedding of secondary filaments epithelium, especially at salinity levels of 10 and 15 ppt. Additionally, the intestines displayed hyperplasia and inflammatory cell infiltration of intestinal mucosa at 5–10 ppt salinity, degeneration and sloughing of the intestinal epithelium at 15 ppt saline water, and increased goblet cell number at salinity of 10 ppt. The study found that continuous TAN exposure had a more significant impact on the fish, especially at higher salinity levels. Water salinity, TAN, and their interaction significantly affected all measured blood bio-indicators (total, albumin, globulin, ALT, AST, creatinine, urea, glucose, and cortisol levels). The phagocytic activity and index were markedly lowered in fish reared in 15 ppt with continuous TAN exposure, while the lysozyme activity was decreased in fish grown in 5, 10, and 15 ppt with continuous TAN exposure. In conclusion, Nile tilapia showed the possibility of growth with normal health status in brackish water (5–10 ppt); however, continuous TAN exposure can impair the productivity of tilapia, especially with high salinity (15 ppt).
COVID-19 in the neighbourhood: the socio-spatial selectivity of severe COVID-19 cases in Sweden, March 2020–June 2021
Authors: Kawalerowicz Juta , Cederström Agneta , Andersson Eva , Malmberg Bo
Published: November 2023

In this paper we analyse spatial and temporal variation in the risk of intensive care unit (ICU) admission for COVID-19 in Sweden. The analysis is based on geocoded and time-stamped data from the Swedish Intensive Care Registry (SIR). We merge this data with a classification of Swedish neighbourhood cluster types constructed from multi-scalar measures of socio-economic and country of birth segregation (Kawalerowicz and Malmberg in Multiscalar typology of residential areas in Sweden, 2021 available from https://doi.org/10.17045/sthlmuni.14753826.v1). We examine 1) if residence in more socio-economically deprived or diverse neighbourhood cluster types was associated with a higher risk of ICU admission for COVID-19, 2) if residence in more affluent neighbourhoods was associated with a lower risk of ICU admission for COVID-19, and 3) how these patterns changed over time during the three first waves of the pandemic. While the highest overall risk was associated with residence in urban disadvantage coupled with diversity, models where neighbourhood cluster types were interacted with waves reveal that the highest risk was associated with living in a neighbourhood cluster type characterised by rural town disadvantage coupled with diversity under the 3rd wave (February 2021–June 2021). Residence in such a neighbourhood cluster type was associated with a four times higher risk of ICU admission, compared to the reference category of living in a homogeneous rural neighbourhood cluster type with average levels of deprivation under wave 1. Looking at disparities within each wave we found that residence in most affluent urban areas was at first associated with a slightly higher risk of ICU admission for COVID-19 as compared with the reference category of living in a homogeneous rural neighbourhood cluster type, but under waves 2 and 3 this risk was no longer statistically significant. The largest inequalities between different neighbourhood cluster types could be seen during the 1st wave. Over time, the risks converged between different neighbourhood cluster types.
Argan Oil Trade and Access to Benefit Sharing: A Matter of Economic Survival for Rural Women of the Souss Massa, Morocco
Authors: Montanari Bernadette , Handaine Mohamed , Id Bourrous Jamila
Published: November 2023

Poverty eradication, environmental conservation, and the United Nations Sustainable Development Goals cannot be achieved without the input and participation of disadvantaged communities in developing mitigation strategies. Over the last few decades, the markets for natural resources as niche products have grown exponentially. Morocco’s production and international sales of argan oil are set to exceed current figures within the decade. We interviewed presidents of cooperatives in several villages in the Souss Massa region of Morocco to assess the current status of the argan oil trade, in particular women’s roles in production, their economic status, and whether they have access to benefit sharing (ABS). Our results reveal that control over the argan oil trade has shifted into intermediaries that supply larger corporations, and that the survival of cooperatives and women’s access to vital income are increasingly threatened. We argue thatthe implementation of ABS is essential to preserve women’s access to income and their traditional knowledge associated with oil extraction processes and to ensure the conservation of argan ecosystems as prescribed by the Nagoya Protocol.
Optimum Optical Designs for Diffraction-Limited Terahertz Spectroscopy and Imaging Systems Using Off-Axis Parabolic Mirrors
Authors: Chopra Nishtha , Lloyd-Hughes James
Published: November 2023

Off-axis parabolic mirrors (OAPMs) are widely used in the THz and mm-wave communities for spectroscopy and imaging applications, as a result of their broadband, low-loss operation and high numerical apertures. However, the aspherical shape of an OAPM creates significant geometric aberrations: these make achieving diffraction-limited performance a challenge, and lower the peak electric field strength in the focal plane. Here, we quantify the impact of geometric aberrations on the performance of the most widely used spectrometer designs, by using ray tracing and physical optics calculations to investigate whether diffraction-limited performance can be achieved in both the sample and the detector plane. We identify simple rules, based on marginal ray propagation, that allow spectrometers to be designed that are more robust to misalignment errors, and which have minimal aberrations for THz beams. For a given source, this allows the design of optical paths that give the smallest THz beam focal spot, with the highest THz electric field strength possible. This is desirable for improved THz imaging, for better signal-to-noise ratios in linear THz spectroscopy and optical-pump THz-probe spectroscopy, and to achieve higher electric field strengths in non-linear THz spectroscopy.
A Review of Task Allocation Methods for UAVs
Authors: Skaltsis George Marios , Shin Hyo-Sang , Tsourdos Antonios
Published: November 2023

Unmanned aerial vehicles, can offer solutions to a lot of problems, making it crucial to research more and improve the task allocation methods used. In this survey, the main approaches used for task allocation in applications involving UAVs are presented as well as the most common applications of UAVs that require the application of task allocation methods. They are followed by the categories of the task allocation algorithms used, with the main focus being on more recent works. Our analysis of these methods focuses primarily on their complexity, optimality, and scalability. Additionally, the communication schemes commonly utilized are presented, as well as the impact of uncertainty on task allocation of UAVs. Finally, these methods are compared based on the aforementioned criteria, suggesting the most promising approaches.
Tighter Bounds on Transient Moments of Stochastic Chemical Systems
Authors: Holtorf Flemming , Barton Paul I.
Published: November 2023

The use of approximate solution techniques for the Chemical Master Equation is a common practice for the analysis of stochastic chemical systems. Despite their widespread use, however, many such techniques rely on unverifiable assumptions and only a few provide mechanisms to control the approximation error quantitatively. Addressing this gap, Dowdy and Barton (J Chem Phys 149(7):074103, 2018) proposed an optimization-based technique for the computation of guaranteed bounds on the moment trajectories associated with stochastic chemical systems, thereby providing a general framework for rigorous uncertainty quantification. Here, we present an extension of this method. The key contribution is a new hierarchy of convex necessary moment conditions that build upon partitioning of the time domain. These conditions reflect the temporal causality that is inherent to the moment trajectories associated with stochastic processes described by the Chemical Master Equation and can be strengthened by simple refinement of the time domain partition. Analogous to the original method, these conditions generate a hierarchy of semidefinite programs that furnishes monotonically improving bounds on the trajectories of the moments and related statistics of stochastic chemical systems. Compared to its predecessor, the presented hierarchy produces bounds that are at least as tight and features new bound tightening mechanisms such as refinement of the time domain partition which often enable the computation of dramatically tighter bounds with lower computational cost. We analyze the properties of the presented hierarchy, discuss some aspects of its practical implementation and demonstrate its merits with several examples.
Inter-industry and intra-industry switching as sources of productivity growth: structural change of Finland’s ICT industries
Authors: Kuosmanen Natalia , Kuosmanen Timo
Published: November 2023

Structural change is an important driver of productivity growth at the aggregate level. While previous productivity decompositions account for the contributions of market entry and exit, they overlook continuing firms that switch from one industry to another. We develop an improved productivity decomposition that accounts for both intra-industry and inter-industry switching, is applicable to both static and inter-temporal settings, and ensures consistent aggregation of firm-level productivity to the industry level. The proposed decomposition is applied to Finland’s information and communication technology (ICT) industry in the first two decades of the 21st century. This industry experienced major structural changes due to the rapid downfall of Nokia, the world’s largest mobile phone manufacturer at the beginning of our study period. Our results reveal that the sharp decline of labor productivity was associated with structural changes, whereas the surviving firms that continued in the same industry managed to improve their productivity. Our results indicate that industry switching can dampen or enhance the productivity impacts of structural change, especially during times of crisis and recession.
“But Everything Else, I Learned Online”: School-Based and Internet-Based Sexual Learning Experiences of Heterosexual and LGBQ + Youth
Authors: Gamson Joshua , Hertz Rosanna
Published: November 2023

Building upon scholarship on sex education, our research aims to understand how youth with a range of sexual identities have experienced school-based sex education, how they have explored sexual content online, and how they see the two in relation to each other. We thus ask: (1) How do youth with varied sexual identities recall experiencing formal school-based sex education from elementary through high school offerings? (2) How do heterosexual and LGBQ + youth utilize the Internet and social media sites for sexual learning? Through in-depth interviews with college students, we find that heterosexual and LGBQ + youth report that formal sex education was both limited and heteronormative; LGBQ + youth felt particularly unprepared for sexual experiences and health hygiene, and sometimes found ways to translate the information provided for their own needs. Despite some overall similarities in online sexual explorations, experiences of online sexual learning proved quite divergent for youth of different sexual identities. Heterosexual youth were likely to search for information on sexual pleasure and entertainment; in contrast, LGBQ + youth sought information to fill in knowledge gaps about non-conforming sexualities, and often used the digital space for identity discovery, confirmation, and affirmation. For both groups, online explorations interacted with offline ones through a back-and-forth in which youth tested out in one arena what they had learned in the other. These findings highlight the dynamic interaction between formal school curriculum, informal online sexual learning, and sexual scripts, identities and practices.
Bootstrapping multiple systems estimates to account for model selection
Authors: Silverman Bernard W. , Chan Lax , Vincent Kyle
Published: November 2023

Multiple systems estimation using a Poisson loglinear model is a standard approach to quantifying hidden populations where data sources are based on lists of known cases. Information criteria are often used for selecting between the large number of possible models. Confidence intervals are often reported conditional on the model selected, providing an over-optimistic impression of estimation accuracy. A bootstrap approach is a natural way to account for the model selection. However, because the model selection step has to be carried out for every bootstrap replication, there may be a high or even prohibitive computational burden. We explore the merit of modifying the model selection procedure in the bootstrap to look only among a subset of models, chosen on the basis of their information criterion score on the original data. This provides large computational gains with little apparent effect on inference. We also incorporate rigorous and economical ways of approaching issues of the existence of estimators when applying the method to sparse data tables.
Tubeless PCNL versus standard PCNL for the treatment of upper urinary tract stones: a propensity score matching analysis
Authors: Hao Yunwu , Shen Xudong , Han Dongbing , Hao Zongyao , Chen Degang
Published: November 2023

Purpose

In this study, the feasibility of tubeless percutaneous nephrolithotomy (PCNL) for the treatment of upper urinary tract stones was investigated.

Methods

From January 2021 to December 2022, the clinical data of 273 patients who received tubeless PCNL (Group A) were studied. The control group includes clinical data from 302 patients (from January 2019 to October 2022) who received standard PCNL (Group B). The baseline characteristics were consistent between the two groups after using the propensity score matching (PSM) method. Compare the preoperative clinical characteristics, postoperative complications, residual stones, catheterization time, and hospital stay between the two groups.

Results

146 pairs of patients were successfully paired through PSM. There was no statistically significant difference in operative time, blood leukocyte counts, haemoglobin decrease, fever, urinary extravasation, sepsis, bleeding, blood transfusion rates, embolism, and residual stones after surgery between the two groups; Postoperative day 1 and discharge day, the VAS pain score in Group A was significantly lower than that in Group B. The catheterization time and hospitalization time of patients in Group A were significantly lower than those in Group B.

Conclusion

According to the inclusion and exclusion criteria, selecting suitable patients for tubeless PCNL is safe and effective, while significantly alleviating pain and reducing catheterization time and hospital stay.
Temporomandibular trauma and reflections on personal evaluation
Authors: Corte-Real Ana , Abreu João , Figueiredo José Pedro , Nunes Tiago
Published: November 2023

The International Consortium Network/Orofacial Pain Special Interest Group focuses on temporomandibular disease diagnosis procedure guidelines as a reference iQAn this scope. Concerning this reference, the aim of this study was to comprehensively analyze injury and sequela frames within European and American approaches to personal damage. A quasiexperimental pilot study of Portuguese orofacial trauma cases in a medico-legal evaluation database was performed with an interrupted time series design. The clinical data were recorded following five criteria of TMJ diagnosis (jaw opening, pain, anatomical deficit, functional deficit, clinical sounds, and occlusal deficit) under three degrees of severity. The injury frame evaluation was recorded in the first-degree stage in all criteria. Pain, as a sequela, was the criterion present in 45% of the sample as spontaneous (20%) or stimulated (25%). Temporomandibular trauma damage evaluation emphasizes the accurate injury diagnosis and sequela framework. Orofacial trauma analysis should focus on the inclusion or exclusion of a TMD diagnosis. This study suggests revising the reference tables on personal damage, considering the inclusion of TMD and its categorization and impact.
A method for estimating physical and economic food access at high spatial resolution
Authors: Campomanes Florencio , Marshall Michael , Nelson Andrew
Published: November 2023

Physical and economic access to food vary spatially. Methods to map that variability at high levels of spatial detail over large areas are scarce, even though suitable datasets and methods exist. Using open-access data for Ethiopia, we developed a method to map the disparities in physical and economic food access at 1-km resolution. We selected 25 access-related variables for 486 geo-located communities from the 2018 Ethiopian Living Standards Measurement Study to create a food access index (FAI). The index was based on a weighted summation of the 25 variables from a principal component analysis (PCA). We then extrapolated the FAI to the rest of Ethiopia using a generalized additive model (GAM) to produce a 1-km resolution FAI map and used that to describe the spatial variability of food access. Economic access had a heavier weight than physical access in the FAI reflecting the fact that proximity to food markets alone is insufficient if one cannot afford food. The GAM had an R2 of 0.57 and a normalized root mean square error of 22.2% which are comparable to measures of model performance in studies that provided micro-level estimates of relative wealth. Peri-urban areas, representing 67% of the population, had relatively low food access, suggesting that these areas should be a priority for infrastructure or economic intervention. The scarcity of detailed spatial information on food access may limit the effectiveness of targeted policymaking to improve food security. The methodology developed in this study uses widely available and carefully selected datasets and can contribute to more spatially detailed estimates of food access in other countries.
The impact of obesity on thyroidectomy outcomes: a case-matched study
Authors: Rossi Leonardo , Becucci Chiara , Iachini Mattia , Ambrosini Carlo Enrico , Renieri Federica , Morganti Riccardo , Pignatelli Francesco , Materazzi Gabriele
Published: November 2023

Obesity is a well-known public health concern in Western World. Accordingly, an elevated number of obese patients undergo thyroidectomy every year. We aim to assess the impact of obesity on intraoperative and postoperative outcomes of patients who undergo thyroidectomy. 1228 patients underwent thyroidectomy at our department between January 2021 and September 2021. We divided patients into two groups according to body mass index (BMI): non-obese (BMI < 30 kg/m2) and obese (BMI ≥ 30 kg/m2). A propensity score approach was performed to create 1:1 matched pairs (matching according to age, gender, diagnosis, nodule size and type of operation). After matching, the final population included 522 patients, equally divided between each group: non-obese group (Group A; n = 261) and obese group (Group B; n = 261). The primary endpoint of the study was the overall rate of postoperative complications; secondary endpoints of the study were operative time, use of energy device and length of hospital stay. The duration of hospital stay resulted longer in Group B (p = 0.002). No statistically significant differences were documented in terms of operative time (p = 0.206), use of energy devices (p = 0.855) and surgical complications (p = 0.429). Moreover, no statistically significant differences were documented considering each specific complication: transient and permanent hypocalcemia (p = 0.336; p = 0.813, respectively), transient and permanent recurrent laryngeal nerve palsy (p = 0.483; p = 0.523, respectively), hematoma (p = 0.779), bleeding (p = 0.178), wound infection (p = 0.313) and cheloid formation (p = 0.412). Thyroidectomy can safely be performed in obese patients. Outcomes resulted comparable; nonetheless, obesity correlates to longer hospital stay.
Capturing student interest in software engineering through gamification: a systematic literature review
Authors: Ngandu Matipa Ricky , Risinamhodzi David , Dzvapatsva Godwin Pedzisai , Matobobo Courage
Published: November 2023

ICT tools in education are widely used to support the aim of achieving learning outcomes by improving critical areas such as student engagement, participation, and motivation. In this study, we examine literature to explore how game elements are used in capturing students’ interest, which the study suggests is fundamental to the teaching and learning of Software Engineering in higher education. Given the potential of alternative ICT tools such as flipped classrooms to increase interest in learning activities, there is a gap in similar literature on capturing interest in gamified environments, which has the potential to improve the achievement of learning outcomes. We applied flow theory to provide a guiding frame for our study. Following a systematic literature review for our data, we analysed 15 papers from the initial 342 articles, which were extracted from IEEE Xplore and Science Direct databases. The main finding in the reviewed papers underscores the positive impact of gamified learning environments on capturing student interest when teaching and learning Software Engineering. While the reviewed papers were not conclusive in identifying the best game elements for capturing students’ interest, we found, that game elements such as points and leaderboards were the most common mechanisms used to advance students' interest when studying Software Engineering courses. The findings also suggest that different game elements are used in gamified environments to increase participation and engagement. The paper adds voice to the practical implications of gamification for teaching and learning. Although our study requires empirical evidence to validate our claims, we believe it sets the stage for further discussion. In the future, comparative studies of game elements in similar environments will be beneficial for identifying the ones that are more engaging and assessing their long-term impacts.
Platform work, exploitation, and migrant worker resistance: Evidence from Berlin and London
Authors: Alyanak Oğuz , Cant Callum , López Ayala Tatiana , Badger Adam , Graham Mark
Published: November 2023

For migrant workers who do not have access to other means of income, the platform economy offers a viable yet exploitative alternative to the conventional labour market. Migrant workers are used as a source of cheap labour by platforms – and yet, they are not disempowered. They are at the heart of a growing platform worker movement. Across different international contexts, migrants have played a key role in leading strikes and other forms of collective action. This article traces the struggles of migrant platform workers in Berlin and London to explore how working conditions, work experiences, and strategies for collective action are shaped at the intersection of multiple precarities along lines of employment and migration status. Combining data collected through research by the Fairwork project with participant observation and ethnography, the article argues that migrant workers are more than an exploitable resource: they are harbingers of change.
The Failed Idea of Judicial Restraint: A Brief Intellectual History
Authors: Carle Susan D.
Published: November 2023

This essay examines the intellectual history of the idea of judicial restraint, starting with the early debates among the US Constitution’s founding generation. In the late nineteenth century, law professor James Bradley Thayer championed the concept and passed it on to his students and others, including Oliver Wendell Holmes Jr., Learned Hand, Louis Brandeis, and Felix Frankfurter, who modified and applied it based on the jurisprudential preoccupations of a different era. In a masterful account, Brad Snyder examines Justice Frankfurter’s attempt to put the idea into practice. Although Frankfurter arguably made a mess of it, he passed the idea of judicial restraint on to Alexander Bickel and others. Today it remains a topic of much academic debate, while Supreme Court Justices occasionally give the idea lip service when it advances outcomes they desire.

I propose that the intellectual history of judicial restraint reflects the all-too-human inability to refrain from exercising power. The founders, focused on the need to mitigate the flaws of human nature in designing the executive and legislative branches, failed to sufficiently foresee how the same flaws would affect members of the judiciary. The failed idea of judicial restraint stands as the legacy of the founders’ mistake.
Unreported Realities: The Political Economy of Media-Sourced Data
Authors: PARKINSON SARAH E.
Published: November 2023

What is the gap between scholars’ expectations of media-sourced data and the realities those data actually represent? This letter elucidates the data generation process (DGP) that undergirds media-sourced data: journalistic reporting. It uses semi-structured interviews with 15 journalists to analyze how media actors decide what and how to report—in other words, the “why” of reporting specific events to the exclusion of others—as well as how the larger professional, economic, and political contexts in which journalists operate shape the material scholars treat as data. The letter thus centers “unreported realities”: the fact that media-derived data reflect reporters’ locations, identities, capacities, and outlet priorities, rather than providing a representative sample of ongoing events. In doing so, it reveals variations in the consistency and constancy of reporting that produce unacknowledged, difficult-to-identify biases in media-sourced data that are not directionally predictable.
Nonlinear interaction of Alfvénic instabilities and turbulence via the modification of the equilibrium profiles
Authors: Biancalani A. , Bottino A. , Del Sarto D. , Falessi M.V. , Hayward-Schneider T. , Lauber P. , Mishchenko A. , Rettino B. , Sama J.N. , Vannini F. , Villard L. , Wang X. , Zonca F. ,   the ASDEX Upgrade team
Published: November 2023

Nonlinear simulations of Alfvén modes (AMs) driven by energetic particles (EPs) in the presence of turbulence are performed with the gyrokinetic particle-in-cell code ORB5. The AMs carry a heat flux, and consequently they nonlinearly modify the plasma temperature profiles. The isolated effect of this modification on the dynamics of turbulence is studied by means of electrostatic simulations. We find that turbulence is reduced when the profiles relaxed by the AM are used, with respect to the simulation where the unperturbed profiles are used. This is an example of indirect interaction of EPs and turbulence. First, an analytic magnetic equilibrium with circular concentric flux surfaces is considered as a simplified example for this study. Then, an application to an experimentally relevant case of ASDEX Upgrade is discussed.
First mesophotic Ecklonia radiata (Laminariales) records within the iSimangaliso Wetland Park marine-protected area, east coast, South Africa
Authors: Qwabe Welly , Samaai Toufiek , Harris Jean M. , Palmer Ryan M. , Kerwath Sven E.
Published: November 2023

A dense Ecklonia radiata (Laminariales) kelp forest extending at least 35 km has been found between 45 and 60 m depth range within the mesophotic zone inside the iSimangaliso marine-protected area (MPA) at the iSimangaliso Wetland park World Heritage Site on the east coast of South Africa. This is the first visual confirmation of the occurrence of E. radiata beds in subtropical South Africa, in an area situated between the tropical and subtropical bioregions, in an area that spans the Natal and Delagoa bioregions of the south-western Indian Ocean, more than 350 km north of its previously documented South African range. The kelp was found to be present across the length of the MPA, but dense beds were present only in the southern Natal bioregion, with sparse occurrences observed elsewhere on soft-coral and sponge-dominated reefs in the upper mesophotic zone. The footage was collected in November 2020, May 2021 and November 2022 during remotely operated vehicle and drop camera surveys of the mesophotic zone inside the MPA. This discovery adds to the body of knowledge on the global distribution of Laminariales populations in deep tropical and subtropical settings and the diversity of habitats within South Africa's largest coastal MPA.