bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Literature Review on Security Challenges In A Hybrid Cloud Database
Authors: Aljehani Shahad , Farooqi Norah
Published: March 2023

Cloud computing paved the way to many technical facilities for companies to develop their business needs in more effective and efficient manner. Combining private and public cloud into so called Hybrid cloud has made a positive leap in business by allowing applications and data to be shared among enterprises. However, many challenges and issues have arisen when adopting the hybrid cloud to manage, store and process data. The most critical one of these challenges is the security of the adopted Hybrid cloud. This research presented a comprehensive study about the security challenges in the Hybrid cloud computing as well as the suggested solutions. The study used a Systematic Literature Review (SLR) process to collect, review and summarize published articles from IEEE and Springer Nature databases and between 2020 and 2021. As a result, there were 7 eligible articles selected according to the search criteria and fully reviewed. The findings have revealed that there are four main challenges which are Data Security, Access Control, Privacy, Data Leakage and Cy- ber Attacks. Future studies should be conducted using different databases to have further investigation regarding the security in Hybrid clouds.
Optimization of wear and cracks in roller contact under different coating and a range of loads and temperature with fixed speed using design expert (DOE) and finite element model
Authors: Nehme Gabi , Al Esber Monzer
Published: March 2023

Superior coating technology and roller materials such as M50 steels (0.8Câ€“4.2Crâ€“4.3Moâ€“1V wt. %) and (1.0Câ€“2.0Crâ€“0.5Moâ€“1.0Mnâ€“ 0.5Si wt. %) are well recognized in modern technology. The aim is to present all the external and internal parameters that affect the rolling system by taking into consideration the microstructure importance in identifying the service life of such rolling technique. The most dangerous defects are the cracks and wear under high loading contact and temperature formed during the rolling process.Finite elements method was used to simulate rolling and to calculate the extensive wear in order to use DOE to optimize several conditions from coating to load and temperature. The analysis involved here used the steel rollers with and without coatings, which include titanium nitride (TiN), zirconium nitride (ZrN), and tungsten carbide (WC) under different temperature and loading conditions. Results showed that cracks propagation were limited to extreme load when using coating technology. Design Expert optimization confirmed that TiN and WC coatings would enhance the lifetime of rollers and inhibit cracks initiations and extensive wear that could results in severe plastic deformation.
Analysis of SIW Crossover for 5G Beamforming Network Applications
Authors: Matar Mohammed A. I. , Cinar Gokhan , Ã‡Ä±nar Ã–zge
Published: March 2023

A Mode-Matching Technique (MMT) with Generalized Scattering Matrix Method (GSMM) are deployed to design and analyze H-plane SIW crossover operating at 26 GHz for 5G beamforming networks applications. The introduced crossover has an 0 dB transmission over more than 4 GHz bandwidth. During the MMT formulation, the crossover structure is divided into two symmetrical cascaded parts with each part having multi-port bifurcated sections. Due to the symmetrical structure, analyzing one half of the coupler with MMT has been sufficient for full analysis. The obtained S-parameter results from MMT are compared with full-wave CST simulator results.
Kinetics studies of phytomedicine mathesia - -butyrolactone interaction
Authors: H. Nkasa L. , C. Mulenga M. , J. Muzomwe M. , J. Kayembe S. , B.  Ilinga L. , Z. Kashongwe M. , P. Ngoy B. , M Taba K.
Published: March 2023

Kinetic studies of the interaction between Â Î³-Butyrolactone and one of the phytomedecines such as Mathesia used for Buruli ulcer treatment were investigated by conductimetry. Î³-Butyrolactone which is the simplest form of lactone was used as probe in order to fully understand how a cyclic ester, such as lactone, could behave in a basic environment. It was observed that for the Mathesia solution at pH 11 the minimal apparent rate constant was around 3.54636 compare to sodium hydroxyde solution at pH 12 where the minimal apparent rate constant was around 3.12295. The apparent rate constants of successive diluted solutions of Phytomedicine Mathesia show up the dilution factor 1: 4. A plot of apparent rate constant versus dilution factor gave a curve with a correlation coefficient of 0.99831.
Solar remote monitoring unit
Authors: Omar M. , Qaiser M. , Usman M. , Tajamal K. , Larkin S. , Raw B. , Khan S.
Published: March 2023

In this manuscript, a smart, IoT-enabled, solar-based datalogger, which can measure AC and DC voltage and current of solar panel accurately is presented. Combination of stand-alone current and voltage sensors are used to measure to develop the datalogger. The datalogger can measure the current non-invasively, without introducing disturbance to the circuit under test. The PCB is fabricated, and measurements have been made to evaluate the system's performance. The results demonstrate that sensed values give maximum accuracy compared to manually tested values. The main purpose of the study is to measure the electrical parameters of solar panels to achieve maximum accuracy, reducing the error rate, thus causing a reduction in electricity bills, and accessing the data remotely. The system can send data to the cloud so that a remote user can check the data through a web-application.
A conceptual framework to guide the development of a transition support programme to facilitate the competencies of newly qualified registered nurses at public hospitals in Namibia
Authors: Emvula Olivia , Pretorius Louise , Amakali-Nauiseb Taimi
Published: March 2023

Purpose: Newly qualified registered nurses often lack the competence to efficiently execute their professional roles and responsibilities. They might fail to execute their nursing functions and make clinical judgement because of lack of confidence. The aim of the study is to develop a conceptual framework as basis for the development of a transition support programme to facilitate the competencies of newly qualified registered nurses (NQRNs) at public hospitals in Namibia.
Methods: The Programme Logic Model (Knowlton & Phillips, 2013 was adapted as it allowed the researcher to present the conceptual framework in a systematic and visual way, while presenting and sharing the ideas and understanding of the relationships among the resources needed to develop the transition support programme, the planning of programme activities, and the changes or results you hope to achieve.
Results: The results of the development of the conceptual framework served as basis for the transition support programme to facilitate the competencies of newly qualified registered nurses.
Conclusion: The conceptual framework could serve an effective tool in guiding the development of the transition support programme to facilitate the competencies of newly qualified registered nurses.
Coronavirus disease 2019 in an elderly patient who became severely ill despite antibody cocktail therapy but improved with lung-protective management: A case report
Authors: Mitsutome Eriko , Une Kazunobu , Nakanuno Ryuichi
Published: March 2023

Casilivimab/imdevimab, called antibody cocktail therapy, is a treatment for mildly and moderately ill COVID-19 patients. In our care facility, we encountered an elderly patient treated with an antibody cocktail after being diagnosed with a moderate disease at the initial presentation that became severe. An 80-year-old man with a history of diabetes, hypertension, and cerebral infarction presented with a 5-day history of fever and was diagnosed with coronavirus disease 2019. He was diagnosed with moderate disease and immediately ad-ministered the antibody cocktail therapy. However, his respiratory status deteriorated rapidly, and mechanical ventilation was initiated. We performed lung-protective ventilation, centered on low tidal volume and prone position therapy, with good outcomes. Throughout the pandemic, his case, as well as others, highlighted that immediate intervention for mild and moderate cases and intensive treatment, such as lung-protective ventilation and prone position, for severe cases improved patient outcomes.Â Â Â
Plasmon energy and microhardness of BxAl1-xSb alloys: semi-empirical prediction
Authors: Mezouar Rabie , Logzit Nacer
Published: March 2023

Based on the reflective index reported in the literature, the present work aims to investigate the plasmon energy, the microhardness and the homopolar band gap energy of BxAl1-xSb ternary semiconducting alloys as a function of boron concentration x in the range 0 –1. We found that both the plasmon energy and the microhardness of BxAl1-xSb alloys change gradually but not monotonically with increasing of boron concentration x from 0 to 1, while the homopolar band gap energy increases monotonically with enhancing of x.
We emphasize that a boron concentration x dependent plasmon energy and microhardness between 0 and 1 is extremely unusual behavior for BxAl1-xSb alloys. Normally, both plasmon energy and the microhardness monotonically increase with increasing boron concentration x as it was mentioned in the literature. The plasmon energy of AlSb and BSb was found to be 16.14 and 15.58 eV, respectively. Our value (16.14 eV) of the plasmon energy for AlSb compound is higher than the result (13.8 eV) reported by Böer and Pohl. The minimum of the plasmon energy was found to be 14.4 eV for both B0.5Al0.5Sb and B0.625Al0.375Sb alloys.
The microhardness of AlSb was found at around 7.56 GPa, while that of BSb was found to be 6.51 GPa. Similar to the plasmon energy, the minimum value of the microhardness was found to be 4.45 GPa for both B0.5Al0.5Sb and B0.625Al0.375Sb alloys.
New novel physical constants metric and fine structure constant models demonstrate the intrinsic nature of vacuum space as a quantum medium
Authors: Markoulakis Emmanouil , Wolf Christian
Published: March 2023

We hereby display two independent research-wise blind folded calculations of the fine structure constant using different angles in attacking the problem by two different novel models that however produced the same result which leads to the inescapable conclusion that 'empty' vacuum space must be intrinsically a quantized medium in nature.
Evaluating the protective impact of pumpkin seeds oil against ciprofloxacin induced hepatorenal toxicity in the male albino rats
Authors: Sabry Abd El-Shafi Ahmed Hanan , A. A.Elkomy Ashraf , A.H. Farag Enas
Published: March 2023

Background: Ciprofloxacin increased the production of reactive oxygen species, As a result of its intracellular accumulation, which leads to extracellular membrane damage, resulting in the release of apoptotic components into the bloodstream, a condition known as apoptosis.Objective: The goal of this study is to investigate the protective effect of pumpkin seeds oil (PSO), a well-known natural antioxidant against Ciprofloxacin-induced liver and kidney impairment (CPFX[i]).Material and methods: Forty-Four male albino rats weighing approximately 180â€“200 gm were formed. (n = 10): (1) control saline, (2) PSO [ii] (4ml/kg/day orally for 4 weeks), (3) CPFX (80mg/kg/day orally for 2 weeks), and (4) PSO (4ml/kg/day orally for 4 weeks) + CPFX (80mg/kg/day orally for 2 weeks), starting on the first day of the third week. Finally, Serum and tissue specimens are collected at the conclusion of the experiment for biochemical and histopathological examination. Results: It ended up being found in the CPFX-treated group. ALT [iii], AST [iv], and TNFÎ±[v] levels were all significantly elevated in the serum. While this medication reduced the hepatocellular content of GSH [vi], it increased the tissue content of MDA [vii], which clearly shows oxidative stress Reduced BCL2[viii] levels also indicate the presence of apoptosis. CPFX causes an increase in kidney-specific markers such as creatinine and urea, indicating kidney disease. When PSO was combined with CPFX BAX [ix], MDA, AST, ALT, and TNFÎ± levels were considerably reduced, while GSH and BCL2 levels increased, indicating that PSO has antioxidant action and reduces apoptosis. Additionally, the renal function parameters improved, as seen by lower serum creatinine and urea levels.Conclusion: In rats, employing PSO as a concurrent prophylactic therapy while administering CPFX effectively reduced CPFX-induced oxidative stress and apoptotic damage. PSO could be used as a preventive medication to prevent CPFX-induced cellular damage to the kidneys and liver.Â Â Â
Software engineering's role in visualizing large data as medical datasets
Authors: Abdel Amir Sebti Hind , A. Najim Safa
Published: March 2023

Although both 'information visualization' and â€˜software engineering visualization' are data collection operations, their motivations are clearly distinct. The visualization of software engineering integrates the original design modules and identifies the connections between the main components. The purpose of software engineering is to develop high-quality programs and create appropriate work. The goal of visualization is to get insight into many components of a process we are interested in, such as a scientific simulation or a real-world process, using interactive graphs. Medical imaging techniques are used to detect and comprehend illness progression in the human body. To be able to make a diagnosis concerning it. In health centers and hospitals, managing vast collections of medical pictures is a challenge. Because the image database has grown in size over the last year, meaningful information is needed to assist the specialist in assessing the patient's condition. In this review, we will highlight some of the techniques that we use in data analysis.Â Â Â
Peranan Taurin pada Pertumbuhan dan Kelangsungan Hidup Larva Ikan Kerapu Bebek Cromileptes altivelis (Valenciennes, 1828)
Authors: Melianawati Regina , Astuti Ni Wayan Widya , Tridjoko Tridjoko
Published: March 2023

Taurine is an important amino acid for the growth of marine fish larvae The humpback grouper (Cromileptes altivelis) is a highly valuable marine fish that has been farmed in hactheries. The increasing of larval growth and survival rate of humpback grouper was carried out by taurine addition as enrichment ingredient to zooplankton as live feed for larvae. The purpose of this study was to find out the role of taurine on larval growth and survival rate. Two treatments tested were taurine addition by bioencapsulated through zooplankton rotifers Brachionus rotundiformis (A) and without taurine addition in rotifers (B). The observed parameters were larval growth and survival rate. Larval samples were taken on day 1 and 5, then continued every 5 days until the end of the study, by using10 larval samples at each time. The results showed that mostly all  larvae have already metamorphosed and become juveniles at 35 days old. At that time, larvae with taurine addition (A) have bigger in size, faster growth and also higher survival rate compared than larvae without taurine addition(B). Therefore, the result of this study indicated that the addition of taurine could improve larval growth and the survival rate of humpback grouper.   Taurin merupakan asam amino penting untuk pertumbuhan larva ikan laut. Ikan kerapu bebek (Cromileptes altivelis) adalah salah satu jenis ikan laut bernilai ekonomis tinggi yang sudah dapat dibudidayakan. Peningkatan pertumbuhan dan kelangsungan hidup larva ikan kerapu bebek dilakukan dengan penambahan taurin sebagai bahan pengkaya ke dalam zooplankton sebagai pakan alami larva. Tujuan penelitian ini adalah mengetahui peranan taurin pada pertumbuhan dan kelangsungan hidup larva. Dua perlakuan yang diujikan adalah penambahan taurin melalui bioenkapsulasi pada zooplankton rotifer Brachionus rotundiformis (A) dan tanpa penambahan taurin pada rotifer (B). Parameter yang diamati adalah pertumbuhan dan kelangsungan hidup larva. Sampel larva diambil pada umur 1 dan 5 hari,  selanjutnya setiap 5 hari sekali hingga akhir penelitian, dengan menggunakan 10 ekor larva setiap waktu pengambilan sampel.  Hasil penelitian menunjukkan bahwa sebagian besar populasi larva telah bermetamorfosis menjadi juvenil pada umur 35 hari. Pada umur tersebut, larva yang diberi penambahan taurin (A) memiliki ukuran yang lebih besar, pertumbuhan yang lebih cepat dan tingkat kelangsungan hidup yang lebih tinggi dibandingkan dengan larva yang tidak diberi penambahan taurin (B). Oleh karenanya, hasil penelitian ini menunjukkan bahwa penambahan taurin pada rotifer dapat meningkatkan pertumbuhan dan kelangsungan hidup larva ikan kerapu bebek.
Impact of Migration on Language: The Case of Curaçao
Authors: Goede Miguel
Published: March 2023

Purpose: The purpose of this article is to analyze the influence of migration on the Papiamento language in Curaçao. Methodology: The paper draws from published articles and reports on migration, data from the Bureau of Statistics, and interviews with key informants. Findings: Although the position of Papiamento has changed, the magnitude of this change and the reasons behind it are difficult to determine due to the lack of official data. Originality: The article is part of a larger body of work addressing this phenomenon. The evidence provided in Small States & Territories offers a valuable perspective on the impact of migration on language. Conclusions: Although the position of Papiamento language has experienced fluctuations in the past, it remains very strong and is value to Curaçao community is expected to remain stable. Paper type: Inventory study
The “Arbitral Immunity” Dilemma – What is the Balance?
Authors: Fulena Viraj , Chittoo Hemant B.
Published: March 2023

As recipients of bad news are inclined to blame the messenger, a losing party in arbitration will tend to blame the arbitrator. Arbitrators will usually respond by asserting the doctrine of arbitral immunity. The main objective of this paper is to investigate how arbitrators and the parties who appointed them are protected from certain liabilities imposed on them. Since arbitrators carry out some judicial or quasi-judicial functions that render them comparable to judges, is it fair to compare them to court judges? Do they possess the same powers as court judges? It is often said that arbitrators should be treated as mere professionals hired to provide their services and they should not be protected by the shield of immunity. Some scholars would argue that if immunity is not granted to them, they will work under constant fear of reprisals from unsatisfied parties. Emphasis, in this paper, is laid on the similarities and differences between arbitrators and judges and also in how different legal and arbitral rules approach the concept of arbitral immunity under different jurisdictions. Also, a comprehensive analysis is made on how arbitrators and aggrieved parties to the arbitration are duly protected. A close examination is also undertaken on how to improve the system and move towards a more unified model. After having critically analyzed the basis of arbitral immunity, it is firmly believed that some degree of immunity is important in order to maintain the independence and impartiality of the arbitration process. It can be postulated that arbitral immunity should be qualified and not absolute. By qualified immunity it is understood that when an arbitrator has committed gross negligence, has had a willful conduct or has acted in bad faith, he should not be shielded by the blanket of immunity.
Pain assessment 3 × 3: a clinical reasoning framework for healthcare professionals
Authors: Bäckryd Emmanuel
Published: March 2023

Objectives

To give an overview of central aspects of pain medicine-specific clinical reasoning when assessing a pain patient. Clinical reasoning is the thinking and decision-making processes associated with clinical practice.

Methods

Three core pain assessment areas that are crucial for clinical reasoning in the field of pain medicine are discussed, each of them consisting of three points.

Results

First, it is important to distinguish acute, chronic non-cancer, and cancer-related pain conditions. This classical and very simple trichotomy still has important implications treatment-wise, e.g., concerning the use of opioids. Second, the pain mechanism needs to be assessed. Is the pain nociceptive, neuropathic, or nociplastic? Simply put, nociceptive pain has to do with injury of non-neural tissue, neuropathic pain is caused by a disease or lesion of the somatosensory nervous system, and nociplastic pain is believed to be related to a sensitized nervous system (c.f. the concept of “central sensitization”). This also has implications concerning treatment. Some chronic pain conditions are nowadays viewed more as diseases rather than the pain being merely a symptom. In the new ICD-11 pain classification, this is conceptualized by the characterization of some chronic pains as “primary”. Third, in addition to a conventional biomedical evaluation, psychosocial and behavioral aspects must also be assessed, the pain patient being viewed as an active agent and not merely as the passive recipient of an intervention. Hence, the importance of a dynamic bio-psycho-social perspective. The dynamic interplay of biological, psychological, and social aspects must be taken into account, putative behavioral “vicious circles” thereby being identified. Some core psycho-social concepts in pain medicine are mentioned.

Conclusions

The clinical applicability and clinical reasoning power of the 3 × 3 framework is illustrated by three short (albeit fictional) case descriptions.
Features of competitive activity in different types of martial arts
Authors:   Dnepropetrovsk professional college of sports, Pyroh Y.
Published: March 2023

Purpose: on the basis of the analysis of scientific and methodical information and Internet networks, generalization of the best practical experience to establish the features of competitive activity in different types of martial arts. Material and methods. The following research methods were used to establish the features of competitive activity in various types of martial arts: analysis of scientific and methodological information and the Internet, generalization of best practices. Results: the analysis of scientific and methodical information, Internet sources and generalization of the best practical experience allowed us to determine that the problem of studying competitive activity in martial arts is one of the most urgent. In modern martial arts, the competitive struggle is becoming more and more intense, the political, social and economic significance of sports achievements is growing, the issues of scientific substantiation and improvement of the management of athletes' training are becoming increasingly important. Successful and effective management of sports training is impossible without a sound analysis of modern competitive activity. It is established that for the training of high-class martial artists it is important to timely inform athletes and coaches about the promising directions of the development of the sport. At the same time, the analysis of the competitive activity of the leading martial artists of our time and national teams is relevant. Conclusions. The results of the research showed that the analysis of competitive activity was carried out: in order to determine the features of modern competitive activity; to establish various parameters and basic technical and tactical actions that are most often used; to assess the strengths and weaknesses of the preparedness of athletes; to modulate the skills of the strongest martial artists in the world; forecasting future sports results in competitions, etc. The conducted research makes it possible to assert that the analysis of modern competitive activity should be used to improve the training process of athletes in martial arts.
The effectiveness of the use of rhythmic stimulation to improve the speed of reaction and technical and tactical preparedness of qualified boxer
Authors:   National Technical University «Kharkiv Polytechnic Institute», Fedoryna T. , Dolhareva M. ,   National Technical University «Kharkiv Polytechnic Institute», Yefremenko A. ,   Kharkiv State Academy of Physical Culture, Krainyk Y. ,   Kharkiv State Academy of Physical Culture
Published: March 2023

Purpose: to investigate the influence of the application of the rhythm stimulation program on the dynamics of reaction rate indicators and technical and tactical preparedness of qualified boxers. Material and methods. Objects: 20 boxers aged 16,45±0,55 years with 7,30±1,55 years of training experience. The objects were divided into two equal groups (1 and 2) according to the results of the preliminary testing and did not differ significantly in terms of measured indicators (p>0,05). Methods: pedagogical observation, testing and experiment; reaction measurement; video shooting and video analysis. Results: аn analysis of input and output control indicators obtained as a result of testing was carried out. It was established that during the period of the study there were significant changes in all indicators of speed in athletes of groups 1 and 2 (р<0,05). An intergroup comparison of the test results at the end of the study revealed significantly higher values of the indicators of the speed of execution of striking combinations in the boxers of group 1. Modern sports training requires finding ways to increase the effectiveness of training with the use of natural stimulants. It was assumed that the use of rhythmic audio stimulation as a component of training tools for boxers will contribute to increasing the speed of execution of technical and tactical elements of boxing. The impact of the use of rhythmic stimulation in the training of boxers was established in terms of improving the speed of execution of technical and tactical elements, but not the speed of reaction. Thus, the use of rhythm stimulation in the training of experienced boxers in the preparatory period is justified and allows comprehensive and concentrated improvement of speed abilities in the annual macrocycle of training. Therefore, this approach is a promising way to overcome stagnation in the process of improving the speed of technical and tactical elements, which is observed in boxers of this age group and older. Conclusions. The obtained data contribute to the deepening of understanding regarding the improvement of the manifestation of various components of the speed abilities of experienced boxers. The use of rhythmic stimulation in the training of boxers will contribute to the improvement of the training process without changing the structure of the training process in the preparatory period, but as a qualitative addition to it. Further research will concern the use of rhythm stimulation in work with young boxers.
Goldenhar Syndrome
Authors: Chauhan Anubhav , Chauhan Shveta
Published: March 2023

Goldenhar syndrome is a hereditary condition which is characterized by preauricular appendages, epibulbar dermoids, along with anomalies of the heart, kidney, and vertebral, central nervous and gastrointestinal system. We report a case of Goldenhar syndrome in a 7-years-old male patient who presented with limbal dermoid, pre auricular tag, microtia and mandibular hypoplasia. We AIM to report this case, given the rarity of this syndrome, and classical signs seen in our patient.
Ibn al-Haytham, the Arab who brought Greek optics into focus for Latin Europe
Authors: McQuaid Robert
Published: March 2023

Ibn al-Haytham remains an unknown figure in the development of optics from the ancient Greeks to Latin Europe. He put to rest the idea of visual rays being emitted from the eye, demonstrating vision occurs by intromission of light rays to the eye. Through observational experimentation he characterized the behavior of light and described many visual phenomena that are now considered visual perception. Ibn al-Haytham’s most significant work, Kitab al-Manazir was written in the eleventh century and was translated to Latin, as De aspectibus during the middle of the thirteenth century. Its introduction to Latin Europe stimulated the study of optics within the nascent universities of Europe and provided a model to conduct experiments and influenced natural philosophers for centuries.
Effects of an arm cycloergometer session on morbid obese women (acute exercise effect on morbid obese women)
Authors: Monnerat Marino Rosa Felipe , Carlos Quaresma Jose , Regis Joao , Carneiro Ivar , Bender Braulio Valeria , Andre Castilha Fabio , Pires de Carvalho Denise , Fernandes Filho Jose , Vidal Linhares Renato
Published: March 2023

Introduction: The number of morbidly obese individuals has risen in percentages in comparison with different obesity levels and there are very few studies exploring the possibilities of physical exercise for such population. Objectives: Verify the possibility of morbid obese to perform a 30-minute session of mild to moderate continuous aerobic exercise, analyzing the Excess Post-exercise Oxygen Consumption (EPOC) 30 minutes after exercise in addition to the acute cardiovascular effects. Materials and methods: A clinical study was developed with 14 obese, morbidly sedentary pre-bariatric surgery women, aged between 28 and 51 years old. The patients took part in a clinical analysis, which consisted of body composition, maximal stress test and a 30 minutes-exercise session in an arm cycle ergometer, preceded by 3 minutes of warm up before any physical examination. A mild to moderate intensity was used at a reserve heart rate (HR) between 55 and 69% of maximal heart rate at moderate intensity. Energy exercise expenditure, EPOC, and the acute responses of the HR, blood pressure (BP) and oxygen saturation were checked and analyzed. Results: Out the 15 patients evaluated, 14 were able to complete the prescribed exercise session within an average expenditure of 131.5 kcal in the exercise and 37.2 in EPOC. The only patient who could not complete the task was due to pain in her shoulder. No patient demonstrated desaturation or abnormalities for HR and BP. Conclusions: These findings indicate that physical exercise in an arm cycle ergometer may be an alternative at improving health levels of morbidly obese patients, as it does not promote oxygen desaturation and shows expected standard responses for heart rate and blood pressure.
Recombinant lectins as pioneering anti-viral agents against COVID-19
Authors: Abdullah Saad Dr. Ashraf
Published: March 2023

The primary target for vaccine design and anti-viral therapeutics for the deadly severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) is the coronavirus surface spike (S) glycoprotein. Like other enveloped viruses, S glycoproteins are masked by a dense sugar “coat” of host-derived glycans that mediate immune evasion by molecular mimicry through shielding the immunogenic surface proteins from host immune responses. Paradoxically, this same protective glycan shield can make these sugar-coated viruses vulnerable to immune attack by soluble lectins of the innate immune system that are still able to recognise these glycans as pathogen-associated molecular patterns (PAMPs) leading to complement activation. In reality, recombinant lectins that target virus-associated glycans have the potential to be used as anti-viral agents; and therefore, binding of recombinant lectins to viruses could represent a paradigm shift for viral infection therapy. Likewise, SARS-CoV-2- associated glycans can offer novel targets for recombinant lectins as innovative anti-SARSCoV-2 agents. Unfortunately, pharmacological hurdles currently constrain the entry of recombinant lectins into clinical trials but more vigorous research into potentially useful modifications of these agents can truly develop a new landscape of anti-viral lectin-based therapeutics.
Implementation of six sigma in clinical laboratory a new Persuation
Authors: Kapil Menka , Gupta GN , Sareen Rateesh
Published: March 2023

Quality is simply defined as doing right things for the right people, at the right time and doing them right Quality is simply for the first time. It is a process which involves patient centered care, safety, effectiveness and efficacy. Achievement and maintainance of quality needs stringent control in clinical laboratory. Lack of quality is a burden to the society that can be measured in lost lives and wasted resources. So the quality measures are urgent attention. For improvement in quality six sigma principle has to be applied in clinical laboratory. Although the cost increases a little bit but the money spent on implementation of six sigma are eventually realized by eliminating rework, reducing errors and increasing patient volume.
Distribution patterns and habitat preferences of medium and large mammals of the order Rodentia in the Carcarañá river basin, Southern Santa Fe province, Argentina
Authors: Rimoldi Pablo Guillermo
Published: March 2023

This contribution analyzes the distribution patterns and habitat preferences of wildlife in highly anthropized environments. Considering that the pampas grasslands are one of the most modified natural ecosystems in the world and that both the capybara (Hydrochoerus hydrochaeris Linnaeus, 1766) and the coypu (Myocastor coypus Molina, 1782) have historically been some of the most characteristic mammals of this ecosystem, it is from these two species that the environmental variables that best explain their distribution and affectation will be analyzed.
CT evaluation of aortic dissection and other acute aortic syndromes: An update
Authors: Awa Sandeep Singh , Prasad Niharika , Biswas Som
Published: March 2023

Acute aortic syndromes consist of aortic dissection, intramural hematoma, penetrating aortic ulcer, and ruptured aortic aneurysm. Acute aortic syndromes are considered a clinical emergency with patients presenting with severe chest pain. MDCT is considered as the investigation of choice to evaluate and classify acute aortic syndromes. Correct diagnosis and prompt management of acute aortic syndromes are imperative to reduce mortality and morbidity. Hence, imaging departments must have a basic understanding of their pathophysiology, imaging characteristics, and possible complications, this article reviews the updates in CT imaging of these syndromes and their pitfalls.
Artificial intelligence in radiology education
Authors: Biswas Som
Published: March 2023

Objectives: Artificial intelligence can learn without explicit instructions and has multiple applications in radiology. Whereas many publications have focused on teaching radiologists about artificial intelligence, our goal in this study is to focus on how artificial intelligence can teach radiology trainees better. Key Findings: Although the idea of using artificial intelligence to improve education is not new, the application of artificial intelligence to radiology education remains limited. Based on the limited research that has been published on its current status we highlight some of the developments that have occurred in this field. Conclusion: Artificial Intelligence can be used to enhance radiology education. Implication for practice: Radiologists and radiographers should know the latest trends in Artificial Intelligence to utilize in departmental education.
Policies and practices-Concrete opportunities in response to the Covid19 pandemic in the eastern mediterranean region: systematic scoping review
Authors: Hussain Hamid Yahay , Rebai Wafa Kammoun , Bouguerra Hind
Published: March 2023

Backgrounds: The response Covid19 pandemic by different EMR national and regional health systems reflected tangible fragility and clear weakness pandemic in management at the policy and practice level in the face of rapid epidemic spread and steadily accelerating mortality and morbidity. Many lessons can be learned from the exuberance of the existing pandemic, as pandemic control measures were not guided by strong local evidence and were not tailored to national contexts. In this review, we sought to assess the gaps and challenges of COVID-19 control measures in Eastern Mediterranean Region during the early months of the pandemic
Dynamics of physico -chemical properties of soil in response to hilly aspects in community forest, Rampur Palpa
Authors: Bhattrai Janak , Asheshwar Mandal Ram , Bhakta Mathema Ajay , Jnwali Nirmal
Published: March 2023

This research was objectively conducted to assess physico-chemical properties of soil among aspects. Total 64 soil samples were collected from 0 to 10 and 10-20 cm depths from North East, South East, North West and South West aspects. The physical and chemical properties of soil were analyzed in the lab. Average moisture content was found highest at North East aspect (39.46±1.11%) at 0-10 cm depth and 37.52±0.96 % at the depth of 10-20 cm. Nitrogen content was the highest 0.378±0.03% at 0-10 cm depth and 0.362±0.04 % at 10-20 cm depth in North East aspect. The amount of Potassium in the forest was found highest at North East aspect with the mean ±SE value of 523.76±75 kg/ha at 0-10 cm depth and 418.92±28.09 kg/ha at 10-20 cm depth. Phosphorus content was found to be highest again at North East aspect which has the mean±SE value of 28.202±2.22 kg/ha at 0-10 cm depth and 25.89±2.51 kg/ha at 10-20 cm depth, Similarly, organic carbon content was found highest again at North East aspect with mean±SE value of 2.18±0.06 % at 0-10 cm depth and 2.031±0.05 % at 10-20 cm depth. Elucidating pH content, the highest value was found at North West aspect with mean value of 6.32±0.19 at 0-10 cm depth and 6.02±0.21 at 10-20 cm depth respectively. Value of C:N at North Eastern aspect was recorded 5.80 at 0-10 cm depth and 5.55 at 10-20 cm depth. The study will be useful for researcher for the further work in soil science.
Industrial heritage of a lumber company in Santa Catarina state, Brazil: considerations about industrial archaeology and the history of material culture
Authors: Teixeira Lino Jaisson
Published: March 2023

The current article introduces industrial landscape formation in Brazil’s southern backcountry early in the 20th century, and the implementation of a large log extraction and processing complex – the extracted lumber was well preserved in midwestern Santa Catarina State up to that time. The operation of large lumber processing facilities (including the construction of company-town), which was boosted by substantial changes in destruction of the natural environment was little affected by such ventures, at that time. A population of squatters composed of Portuguese-Brazilians and indigenous peoples lived in this area before enterprise was implemented. Subsistence in this region was based on systems that were little systems that had little impact on the environment. The present study focuses on industrial archaeology of the lumber company; thus, we herein present the basic background of both cultural heritage and archaeology studies that have been slowly developed in this area.
The role of spike protein entry inhibitors in the treatment of mild-to-moderate covid-19 in nonhospitalized patients
Authors: Syabbalo  Nightingale 
Published: March 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a deadly pneumonia caused by an enveloped, single-stranded positive-sense RNA (+ssRNA), 29.881 kb betacoronavirus, belonging to the coronaviridae 2B lineage.1 Clinically, about 80% of the patients with Covid-19 develop asymptomatic or mild illness, usually within 12 days, whereas 15-30% progress to severe disease with acute respiratory distress syndrome (ARDS), hypoxaemic respiratory failure, multi-organ failure (MOF), and death.2 Patients with mild or moderate SARD-CoV-2 are individuals who have respiratory symptoms but are not in respiratory distress, and have no multiorgan dysfunction, or other complications of Covid-19 that require hospitalization.3 These patients can easily be treated as outpatients under quarantine. However, these individuals can progress to severe SARS-CoV-2 requiring hospitalization, mechanical ventilation, or extracorporeal membrane oxygenation (ECMO) if they are not treated. SARS-CoV-2 gain entry into host cells via its spike protein (S) which attaches to its cognitive receptor angiotensin-converting enzyme 2 (ACE2). Spike protein entry inhibitors (SPIs), such as bamlanivimab-etesevimab, casirivimab plus imdevimab, sotrovimab, and bebtelovimab have the potential to inhibit endocytosis, and replication of SARS-CoV-2 in host cells. However, the evolving mutations of SARS-CoV-2 has led to the emergency of new variants, such as Delta Plus, and Omicron BA.1, BA.1617, and BA.2 which are resistant to bamlanivimab-etesevimab, and casirivimab plus imdevimab. Henceforth, these doublet biologics are no longer used in many countries, including the USA. Sotrovimab and bebtelovimab are potent to most variants of concern, and BA.1, they are recommended for the treatment of non-hospitalized patients with Covid-19 in countries with high prevalence of Omicron BA. 1. However, sotrovimab has lost activity against BA.2, therefore, it is no longer recommended in all the states and territories in the USA. Currently, only bebtelovimab is the recommend SPI for the treatment of non-hospitalized patients in the USA.
Unilateral epididymal tuberculosis with scrotal fistula: a case report
Authors: Kodithuwakku Lakshani Wasana Hakmana
Published: March 2023

Tuberculosis (TB) affects millions of people globally every year. Although TB is predominantly a lung infection, it can affect almost any organ system in the body. Therefore, the presentation can be highly variable. Extrapulmonary TB accounts for up to 25% of all reported TB cases, and lymphoreticular and genitourinary systems are the most frequently affected. However, male genital TB infection is a rare phenomenon. A clear majority of patients with male genital TB have a concurrent pulmonary infection. We report a male patient presenting with features suggestive of usual epididymo-orchitis who later developed a frank abscess perforation through a scrotal fistula despite repeated antibiotic courses. He was later diagnosed to have epididymal TB without lung involvement. Clinicians need to be vigilant of tuberculous infection when the accepted treatment of bacterial infections invokes poor responses, especially in areas with TB endemicity.
Anti LGI-1 positive encephalitis in an octogenarian: a curious case of recurrent hyponatremia in elderly- a case report
Authors: Nagpal Kadam , Prakash Swayam , Jain RS
Published: March 2023

LGI-1 is mainly expressed in the limbic areas involving temporal cortices and hippocampus. Anti -LGI-1 encephalitis is an autoimmune encephalitis which manifests with cognitive impairment, seizures which are mostly faciobrachial dystonic type and recurrent hyponatremia. We present an 82 year old octogenarian with similar such presentation with recurrent episodes of hyponatremia and cognitive decline having an excellent response to immunotherapy. There has been no mention of a similar presentation in this age group in literature, to the best of our knowledge.
Infective endocarditis in children-pattern, diagnosis, management and short term outcome in Sudan
Authors: Hafiz Elshazali Osama , Elnaeem Mohammed Zahia
Published: March 2023

Introduction: Infective Endocarditis (IE) in children is relatively rare but causes significant morbidity and mortality when it occurs. The incidence of IE in children is increasing worldwide. Objective: To identify pattern, management and short outcome of IE in Sudanese children. Methods: Retrospective notes review of all the children from birth to 16 years old, diagnosed with IE at Ahmed Gasim Children’s hospital, Khartoum North, Sudan. During the 12 month period starting from January 2017. All children who fulfilled Dukes criteria for Definite or Possible IE were included in the study. Results: During the study period 6260 children were admitted to Ahmed Gasim Children’s hospital, 47 patients fulfilled Dukes criteria for IE; Three patients were labelled as Definite and 44 as Possible, The majority of the patients were overfive years old. Of the 47 patients enrolled in the study,34% had normal hearts and 66.0% were known to have structural cardiac disease; out of them, 17 patients (54.8%) were known to have Rheumatic heart disease (RHD) and 14 patients (45.2%) were known to have Congenital Heart Disease (CHD).The hospital mortality was 21.3%. Conclusion and Recommendation: IE in Sudanese children is not rare and is associated with high hospital mortality,the health professionals should have a high index of suspicion to diagnose IE echocardiography and blood culture should be done whenever the possibility of endocarditis is entertained. The children, parents and caregivers of children with structural heart disease should be educated about IE’spresentation and prevention.
Effectiveness of platelet-rich plasma in the treatment of conditions foot orthotics
Authors: Martínez Estupiñan Lázaro Martín , Arce González Manuel Antonio , Aparicio Lázaro Martínez , Moya Roberto Jimenez , Aparicio Leonardo Martínez
Published: March 2023

Introduction: In orthopedics, the use of rich plasma is still controversial, there is no consensus regarding its indications, and use, although its therapeutic usefulness for various conditions is proven, much remains to be studied on this promising topic. Purpose: With our study we intend to assess the clinical effectiveness and efficacy of the treatment imposed according to study groups. Method. A prospective pre-experimental study was carried out in adults with a diagnosis of orthopedic foot injuries, treated at the Orthopedics and Traumatology Service of the General University Hospital "Mártires del 9 de Abril", from January 2018 to December 2022, where the utility of the PRP is used and valued. Results Orthopedic foot injuries are more common in women between 41 and 60 years of age, 15.9% of the sample was treated with infiltration of platelet-rich plasma, pain decreased in all study groups, without However, the group where PRP infiltration is used represents the one with the best evolution of the patients seen in the clinic. Conclusions The results obtained in this study show that the treatment protocol applied is positive in each of the therapeutic options used from the point of view of pain improvement according to the visual analogue scale, highlighting the option of using PRP.