bluuebunny/crossref_metadata_2025 huggingface dataset:
Public Communication Practices and Beliefs Among Conservation Scientists and Practitioners
Authors: Kohl Patrice A. , Warner Sarah E.
Published: November 2021

Public communication is increasingly recognized as a key component in successful natural resource management within government agencies responsible for conservation. However, communication practices and beliefs among government conservation scientists and practitioners are not well studied or understood. Herein, we present the results of a communication survey disseminated to U.S. Fish and Wildlife Service employees working for the agency's Ecological Services program, a program charged with endangered species recovery. We asked respondents about public communication practices and beliefs, and factors that may motivate or discourage participation in public communication activities. Study respondents reported the lowest levels of participation in media-related, one-way communication activities, including writing educational materials and answering media inquiries. Respondents reported most frequently engaging in one-on-one communication with stakeholders. Although our results suggest that respondents engage in frequent communication with stakeholders, our results also suggest that they mostly communicate with stakeholders remotely, and especially by email, rather than in person. Furthermore, only 36% reported that they go out of their way to visit people in communities. On the other hand, a majority agreed that they learn new things about species and landscapes (80%) from conversations with stakeholders and often use this knowledge to solve conservation problems (89%). With respect to factors that encourage and discourage participation, 93% of respondents indicated that a desire to produce better conservation outcomes motivates them to communicate with stakeholders and the public. Many agreed that a lack of time was an obstacle to participating in public communication (68%), but an even larger majority (86%) indicated that public unfamiliarity with the U.S. Fish and Wildlife Service presented a barrier to public communication. Similarly, a majority of employees agreed that public and stakeholder unfamiliarity with themselves and their work also presented a communication barrier (62%). Our findings suggest that agencies responsible for conservation may want to assess whether the agency and its employees adequately invest in communication activities that foster public familiarity.
Rationalisme communicationnel et rationalisme critique : la place de la philosophie habermassienne dans la pensée éducative contemporaine
Authors: Firode Alain
Published: November 2021

Pour penser le cadre philosophique de leur réflexion, les pédagogues contemporains s’appuient fréquemment sur la théorie du « rationalisme communicationnel » développée par Jürgen Habermas. Quoiqu’il y soit rarement fait référence dans la littérature pédagogique contemporaine, le « rationalisme critique » de Karl Popper constitue une autre tentative pour redonner sens, par-delà les critiques de l’universalisme des Lumières par les auteurs du XXe siècle, au rationalisme et à ses valeurs. De là l’objectif de cette étude, qui est de confronter, sous l’angle de leurs enjeux pédagogiques, ces deux modèles concurrents du « rationalisme ». L’objectif final étant, au travers de cette confrontation, de discuter quelques-uns des problèmes, concernant la formation du sujet rationnel, qui se posent à la réflexion contemporaine sur l’éducation.
Le rapport à l’élève idéal d’enseignants du premier degré : quelles répercussions sur la scolarisation des élèves à besoins éducatifs particuliers ?
Authors: Saunier Déborah
Published: November 2021

En posant les fondements de l’école inclusive, la loi de refondation de l’école du 8 juillet 2013 a bouleversé le quotidien des enseignants. Bien que très majoritairement favorables à la scolarisation des élèves à besoins éducatifs particuliers, les professionnels émettent réserves et ambivalences qui s’expliquent notamment par « le poids des modèles pédagogiques traditionnels qui postulent la conformité des élèves à un modèle d’élève idéal, réussissant et... en bonne santé ! » À partir de données issues d’une enquête quantitative et d’entretiens semi-directifs de groupes, cette recherche interroge l’influence des représentations de l’élève idéal sur les pratiques et l’identité professionnelles d’enseignants du premier degré dans le contexte de scolarisations inclusives. Nos résultats ont permis de dresser un portrait de l’élève idéal et de mettre en évidence des contradictions entre certaines de ses caractéristiques et des profils d’élèves à besoins éducatifs particuliers.
Victor Hugo poète en Italie : perspectives
Authors: Pellegrini Luciano
Published: November 2021

Ce texte précède une anthologie de sept poèmes de Victor Hugo traduits en italien. En Italie, la poésie de Hugo demeure peu lue, peu traduite, peu connue. Dans ce texte d’introduction, j’aborde les raisons de ce manque de fortune italienne du poète qui dure depuis environ un siècle. Je souligne ensuite certaines constantes observables dans les méthodes de traduction des textes de Hugo, pour étayer enfin l’ambition de ces sept traductions réalisées et commentées par des poètes italiens contemporains : celle de contribuer au retour, en Italie aussi, de Hugo poète parmi ceux à qui on ne cesse de redonner la parole.
Dernières formes journalistiques en poésie ?
Authors: Magno Luigi
Published: November 2021

À travers la lecture de quelques travaux publiés vers la fin du XXe siècle et qui s’inspirent directement de la presse des journaux papier (quotidiens, magazines…), cet article esquisse une brève réflexion autour de différentes formes journalistiques de la littérature, voire de la poésie. L’étude réfléchit en particulier à trois stratégies, qui vont du maintien de la forme poétique (Magrelli) à la fabrique de fausses maquettes de journal (Hanna), en passant par différentes démarches conceptuelles (Goldsmith, Cohen, Levé).
Formation interdisciplinaire à la pédagogie dans l’enseignement supérieur : de l’expérience individuelle à la dynamique collective pour impulser une transformation pédagogique
Authors: de la Fouchardière Catherine , Abiad Laure , Laanani Moussa , Lanteri Marine , Maridet Morgane , Tenenbaum Annabelle , Colombet Isabelle
Published: November 2021

Cet article est le fruit d'une collaboration réflexive de cinq enseignants de champs disciplinaires et de structures universitaires différents, avec l’aide de deux conseillères pédagogiques. Il s'agit d'un retour d'expérience à la suite de la participation de ces enseignants à un parcours de formation à la pédagogie universitaire intitulé CertifiENS. Notre propos est surtout de témoigner de cette expérience originale et interdisciplinaire, en décrivant les caractéristiques de notre groupe d’enseignants, le parcours CertifiENS que nous avons suivi puis les transformations pédagogiques que nous avons opérées dans nos enseignements. Nous avons sollicité a posteriori deux de nos conseillères pédagogiques (formatrices dans le cadre du parcours CertifiENS et enseignantes-chercheuses en sociologie et sciences de l’éducation) pour un entretien de groupe (focus group) visant à expliciter nos intentions et motivations initiales et mettre en lumière l'émergence d'une dynamique collective. Cet entretien de groupe nous a permis de porter une analyse réflexive individuelle puis collective sur le processus de transformation individuelle et sur la transition pédagogique effectuée et toujours en devenir.Cette analyse a montré que l’interdisciplinarité a été un atout majeur et une source de synergies, permettant de nous focaliser sur le commun : la pédagogie. Le groupe a été porteur d’une transformation durable des pratiques enseignantes, chacun sur son terrain respectif a souhaité continuer à porter ce changement de paradigme, tout en réfléchissant à la construction d’une communauté de pratiques.
Force Controlled Low Cycle Fatigue (LCF) Life Evaluation Methodology Based on Unstabilized Material Properties
Authors: Men Ilya
Published: November 2021

Low Cycle Fatigue (LCF) is a prominent failure mechanism in many design components; therefore, an evaluation of cycles to failure in this regime is of high importance. Most international standards recommend a closed loop strain-controlled mode specimen testing in this regime. However, the ꜪN data obtained from this test is not suitable for life evaluation of parts enduring force-controlled history during actual service without correction for control mode. Many existing procedures, which accounts for cyclic strain stabilization during force-controlled loading may significantly complicate the finite elements analysis (FEA) at solving or post processing stages and are often an inherent source of uncertainty. A heuristic, cost effective and sufficiently accurate approach for LCF life estimation is advocated. The method involves only two force loading FEA simulations, one of the actual parts and the other of the test specimen, using initial unstabilized stress strain curve, followed by a limited number of force-controlled specimens testing. Actual part and specimen life correlation performed using first loading unstabilized equivalent plastic strain value Ꜫp1 under locality and similitude assumptions. Unstabilized strain vs. number of cycles to failure curve Ꜫp1N is constructed and discussion regarding specimen geometry considerations for providing sufficient accuracy is included. Method validation and crack propagation study are provided.
Simulation and analysis of a Single Mode Indium Gallium Arsenide Phosphide Vertical Cavity Surface Emitting Laser for Optical Communication
Authors: Moatlhodi Ogomoditse Oduetse , Samikannu Ravi , Ditshego Nonofo M.J.
Published: November 2021

This present work is about simulating and analysing a Vertical Cavity Surface Emitting Laser (VCSEL) structure used in optical fibre communication systems. In this paper a VCSEL structure made of seven Quantum Wells of Indium Gallium Arsenide Phosphide (InGaAsP) emitting at 1550 nm is simulated. The device is analysed looking at the following characteristics: Direct current current and voltage (IV) characteristics, light power against electrical bias, optical gain against electrical bias, light distribution over the structure, output power and threshold current. Specification of material characteristics, ordinary physical models settings, initial VCSEL biasing, mesh declarations, declaration of laser physical models, their optical and electrical parameters were defined using Atlas syntax. Mirror ratings and quantum wells are the two main parameters that were studied and analysed to come up with structure trends. By determining important device parameters such as proper selection of the emission wavelength and choice of material; a VCSEL with an output power of 9.5 mW was simulated and compared with other structures.
Management of bone deficiency by metal augmentation in total knee arthroplasty
Authors: Abdeldayem Sherif M. , Zakaria Zeiad M. , Metwaly Radwan G.
Published: November 2021

Background

Inadequate bone stock is frequently encountered in total knee arthroplasty and may be found in primary and revision procedures. Different techniques and devices for their management include additional bone resection, shifting of the components, filling the defect with cement with or without reinforcing screws or mesh, bone grafting, modular metal augmentation, or custom components. The modular augmentations are particularly useful in restoring the proper anteroposterior dimension as well as distal positioning of the joint line. In this study, the authors evaluate the use of metal augmentation for the management of deficient bone stock in total knee arthroplasty.

Patients and methods

A prospective study was done through the period between June 2014 and June 2017 on 30 knee arthroplasties, both primary and revision cases in 28 patients with bone deficiency consistent with Anderson Orthopedic Research Institute type II, treated by metal augmentation using different types of tibial and femoral augments applied to a posterior-stabilized prosthesis. The mean follow-up was 19 months. Eighteen cases (60%) were primary knee arthroplasties, and 12 cases (40%) were revision knee arthroplasties. Assessment at follow-up included clinical assessment through the knee society clinical rating system and radiographic assessment through the knee society roentgengraphic evaluation system.

Results

At the last follow-up, the average clinical knee society score was 80.4 (range from 16 to 93) compared with the average preoperative knee society score of 32 (range from 6 to 51). Only tibial radiolucent lines appeared in zones 1, 2 (nine cases), zones 3, 4 (four cases), and zone 5 in one case. All were nonprogressive radiolucent lines, except for two cases that progressed to aseptic loosening, and only one of them to a varus subsidence of the tibial implant.

Conclusion

Modular metal augmentation is a successful way for reconstruction of bone defects encountered in total knee arthroplasty through preservation of joint line and bone stock.
The Diagnostic Value of Congenital and Nevoid Cutaneous Lesions Associated with Autism Spectrum Disorders in Indian Children- A Case-Control Study
Authors: Varala Sirisha , George Renu , Mathew Lydia , Russell Paul , Koshy Beena , Oommen Samuel P. , Thomas Maya , Muthusamy Karthik , Yoganathan Sangeetha , Jeyaseelan L , Muliyil Jayaprakash
Published: November 2021

Background and Aims:

Cutaneous lesions are the defining features of several neurocutaneous syndromes like neurofibromatosis1(NF1), tuberous sclerosis complex (TSC), and Sturge Weber syndrome to name a few. With this background, we explored the possibility of identifying congenital and nevoid cutaneous markers that may help in the early recognition of autism spectrum disorders (ASD) in Indian children. The objective of this study was to measure the strength of association between congenital and nevoid cutaneous lesions and ASD among Indian children.

Methods:

A case-control study was conducted from January 2018 to June 2018. 132 children (18 months-16 years of age) with ASD and equal number of age and sex-matched children without autism were studied. Diagnosis of ASD was based on DSM-5 criteria. All the children were examined for cutaneous lesions with special attention to nevoid and congenital conditions. The strength of association was measured using the diagnostic odds ratio (OR).

Results:

The prevalence of congenital and nevoid lesions were higher in ASD group (OR = 3.12, P = 0.0001). Among them, pigmentary mosaicism of hyperpigmented type (OR = 2.76, P = 0.02) and café-au-lait macules (CALMs) (OR = 2.40, P = 0.001) were the most prevalent with hyperpigmented pigmentary mosaicism showing a higher association with autism. Atypical CALMs (OR = 2, P = 0.09) were also more prevalent in the ASD group though not statistically significant.

Conclusion:

The presence of hyperpigmented pigmentary mosaicism and CALMs warrant closer surveillance by the caregivers and physicians for evolving features of autism. Larger multicentric studies are required to validate these findings.
Current Use of Ivermectin in Dermatology, Tropical Medicine, and COVID-19
Authors: Mathachan Sinu Rose , Sardana Kabir , Khurana Ananta
Published: November 2021

Ivermectin is a broad-spectrum antiparasitic drug with anti-inflammatory, anti-viral, anti-bacterial, and anti-tumor effects. In this review, we discuss the history, pharmacology, multimodal actions, indications in dermatology and tropical medicine, therapeutic and prophylactic use of ivermectin in COVID-19, safety, adverse effects, special considerations, and drug interactions of ivermectin.
Dermato-Pathologic Clues To Diagnosis Of Adult Onset Still Disease
Authors: Santosh Tummidi , Patra Suman , Goel Garima , Rupla Richa
Published: November 2021

Adult-onset Still's disease (AOSD) is a rare systemic inflammatory condition classically consists of high spikes of fever, morbilliform evanescent skin rash, arthritis, neutrophilic leukocytosis, and multiple organ involvement. However, atypical form of skin rashes has been described with few specific clinical and histopathological patterns that can help in making the diagnosis. A 25-year-old female presented with high spikes of fever, severe debilitating arthritis of peripheral joints, and dusky erythematous flagellate rashes over trunk and proximal limbs. Skin punch biopsy from the cutaneous lesion revealed dyskeratotic keratinocytes in upper epidermis and stratum corneum along with acute inflammatory infiltrate in the dermis: a finding that recently has been found to be constantly associated with this specific pattern of rash of AOSD. The presence of necrotic keratinocytes in upper epidermis and a dermal infiltrate of neutrophils along with characteristic clinical scenario may facilitate earlier diagnosis of AOSD.
Assessment of Patients with Periorbital Melanosis for Hyperinsulinemia and Insulin Resistance
Authors: Thappa Devinder M. , Chandrashekar Laxmisha , Rajappa Medha , Usha R. , Muthupandi K. , Mohanraj Palani S. , Munisamy Malathi , Singh Nidhi
Published: November 2021

Background:

Periorbital melanosis (PM) is one of the most common dermatological condition seen in routine practice. Several cutaneous markers such as acanthosis nigricans have been associated with insulin resistance (IR). However, the association of PM with IR needs to be substantiated.

Objective:

The objective of the study is to evaluate the association of circulating adipokines and IR with PM.

Materials and Methods:

In this cross-sectional study, we recruited 100 patients with PM and 100 age- and gender-matched healthy controls. The serum levels of leptin, adiponectin, fasting glucose, fasting insulin, insulin-like growth factor-1 (IGF-1), homeostatic model assessment of insulin resistance (HOMA-IR), and leptin: adiponectin ratio (L/A ratio) were assayed.

Results:

The serum levels of leptin, fasting glucose, fasting insulin, HOMA-IR, L/A ratio were significantly higher in patients with PM as compared to controls. The serum levels of adiponectin were significantly lower in cases as compared to controls. On multivariate regression analysis, leptin, adiponectin, and HOMA-IR were found to be significant, even after adjusting for BMI, blood pressure and LDL and HDL cholesterol.

Conclusion:

Our findings suggest that patients with PM have hyperinsulinemia, IR, and elevated L/A ratio. PM as a marker of IR in adults may help in identifying patients early and thus aid in the early prevention and management of the disease.
Entodermoscopy Update
Authors: Sonthalia Sidharth , Agrawal Mahima , Bhatia Jushya , Zeeshan Md , Elsamanoudy Solwan , Tiwary Pankaj , Bhat Yasmeen Jabeen , Jha Abhijeet , Bosseila Manal
Published: November 2021

Infectious cutaneous diseases are very common, especially in certain geographic and tropical regions. Sometimes they may simulate other dermatoses, ordering verification of diagnosis with particular investigations. Dermoscopy is among one of the most important tools readily available in the outpatient setting for the dermatologist to confirm the diagnosis. In this up-to date review, literature concerning the various dermoscopic features of parasitic, viral, dermatophytic and bacterial cutaneous infections is composed. In addition artefacts as well as practical issues in dermoscopy usage are discussed; with the aim to empower dermatologists to promptly and non-invasively diagnose and manage cutaneous infections and infestations.
Progressive Osseous Heteroplasia is not an Autosomal Dominant Trait but Reflects Superimposed Mosaicism in Different GNAS Inactivation Disorders
Authors: Happle Rudolf
Published: November 2021

Progressive osseous heteroplasia (POH) is a rarely occurring genetic condition characterized by severe segmental ossification involving the skin and deep connective tissues including the muscles. So far, the disorder is generally described as an autosomal dominant trait. By contrast, the following arguments are in favor of the alternative concept that POH should rather be taken as a non-specific segmental manifestation of different GNAS inactivation disorders such as Albright hereditary osteodystrophy (AHO) with hormone resistance, AHO without hormone resistance, and osteomatosis cutis. Presently, POH has got its own OMIM number 166350 but this is obviously wrong because the disorder does not reflect heterozygosity for a GNAS mutation. Conversely, the disorder is most likely due to an early event of postzygotic loss of heterozygosity with loss of the corresponding wild-type allele. This alternative concept, as proposed in 2016, offers a plausible explanation for the following features of POH. Familial occurrence is usually absent. POH is usually observed in families with one of the three GNAS inactivation disorders as mentioned above. Mosaicism is suggested by the pronounced segmental manifestation of POH and by its lateralization. Some patients have, in addition to POH, bilaterally disseminated features of osteomatosis cutis or AHO, and other patients have family members with one of these nonsegmental disorders. Remarkably, POH tends to appear much earlier than the nonsegmental GNAS inactivation disorders. – Molecular support of the concept was documented in a superficial variant of POH called 'plate-like osteoma cutis'. In several other autosomal dominant skin disorders, molecular corroboration of the theory of superimposed mosaicism has been provided. – For all of these reasons, it is unlikely that POH can further be taken as a distinct autosomal dominant trait. Generation of more molecular data in multiple cases of POH occurring in GNAS inactivation disorders will be crucial to corroborate the proposed concept.
Paraneoplastic Autoimmune Multiorgan Syndrome
Authors: Sathishkumar Dharshini , Agrawal Poonam , Baitule Amey Madhav , Thomas Meera , Eapen Anu , Kumar Sathish , George Renu
Published: November 2021

Background:

Paraneoplastic autoimmune multiorgan syndrome (PAMS), first described as paraneoplastic pemphigus (PNP) is a heterogeneous autoimmune syndrome with a diverse spectrum of clinical and immunopathological features associated with an internal neoplasm.

Materials and Methods:

The details of the patients diagnosed with PAMS/PNP from an Indian tertiary center between January 2010 to December 2019 were retrieved from the hospital database. The clinical manifestations, histopathological features, immunofluorescence findings, and other relevant clinical details were obtained.

Results:

There were eight patients (4 males, 4 females) with PAMS, age ranging from 8 to 46 years (mean 31 years), of whom two were 8-year-old children. The mucocutaneous manifestations were polymorphic and all had recalcitrant oral mucosal involvement. The most common mucosal presentation was pemphigus-like (5/8), and the cutaneous presentation was lichen planus-like (5/8). Castleman's disease (5/8) was the commonest neoplasm followed by thymoma (2/8). Interface dermatitis was seen in all biopsies and three different patterns of direct immunofluorescence were seen, which were intercellular “fish-net” fluorescence in the epidermis (2/8), granular/linear deposition along the basement membrane (4/8) and a combination of both patterns (1/8). Indirect immunofluorescence done on rat bladder in 3 patients showed intercellular “fish-net” fluorescence. Desmoglein levels were not elevated in any of our patients. The follow-up period ranged from 1 to 112.5 months (mean, 23.6 months) with a mortality rate of 12.5%.

Conclusion:

In our study, Castleman's disease was the most common associated malignancy, and the mucocutaneous and histopathological findings were heterogeneous. Timely diagnosis and early intervention improved the outcome in our patients.
Dermatology 2.0- How the Internet is Changing us, our Patients and our Practice
Authors: Mehta-Ambalal Sujata R. , Nisarta Mayuri
Published: November 2021

The internet, in a short span of time relative to the history of modern medicine, has changed us doctors, our patients and our practice. This article reviews these changes and how they have occurred. The write- up was conceptualized after the authors started noticing subtle and overt differences in the consultation and treatment paths of patients who were internet savvy vs. those who were internet naïve. A survey was conducted in the clinic to understand the behavioral changes brought about by the internet among patients of clinical as well as aesthetic dermatology. It must be remembered that these changes are completely new to the practice of dermatology; even small numbers of positive replies are noteworthy. The Covid 19 pandemic has made teledermatology a requisite of the time, rather than an option. Our dependence on technology has never before been so profound. As modern-day dermatologists, we need to be updated about the interactions of dermatology and technology. We must constantly try to optimize the benefits of the internet and minimize its pitfalls. Needless to say, most of the facts mentioned here have been gleaned from the internet itself, from a wide range of sources including but not limited to medical journals, books, news reports, commercial websites and magazines.
Clinicopathological Profile of Childhood Onset Cutaneous Mastocytosis from a Tertiary Care Center in South India
Authors: Sathishkumar Dharshini , Balasundaram Abyramy , Mathew Surya Mary , Mathew Lydia , Thomas Meera , Balasubramanian Poonkuzhali , George Renu
Published: November 2021

Background:

Mastocytosis is characterized by clonal proliferation of mast cells in various organs and can have isolated cutaneous or systemic involvement. Childhood-onset mastocytosis (COM) is usually cutaneous and regresses spontaneously, while adult-onset mastocytosis (AOM) is often persistent with systemic involvement. There is limited data on COM from India.

Objective:

To elucidate the clinicopathological profile of COM.

Methods:

We conducted a retrospective chart review of all the patients with histologically proven COM (≤16 years), presenting over 11 years (January 2009 to December 2019) to the Dermatology Department. We compiled the demographic data, clinical characteristics (morphology, extent, distribution), laboratory investigations, histopathology findings, imaging (ultrasound abdomen), c-KIT mutation results, where available, and other associated abnormalities, and grouped them according to the WHO classification for mastocytosis.

Results:

Among the 66 patients with COM (M: F–1.6:1), 89.4% had onset before 2 years of age. The subtypes were: maculopapular cutaneous mastocytosis (MPCM: 44, 66.7%); mastocytoma of the skin (MOS: 19, 28.8%); diffuse cutaneous mastocytosis (DCM: 2, 3%) and indolent systemic mastocytosis (ISM: 1, 1.5%). Blistering was observed in 29 (43.9%) and Darier sign was elicited in 47 (71.2%) patients. Serum tryptase was elevated in 9/21 (42.9%) patients, but none had systemic mastocytosis. Three patients had c-KIT mutations (two in exon 8 and one in exon 17). Most patients were managed symptomatically and the patient with ISM improved with imatinib.

Conclusion:

MPCM is the most common variant of COM and most patients had a disease onset before 2 years. Overall, COM had a good prognosis with rare systemic involvement, mitigating the need for extensive evaluation routinely in children.
Clinical Photography in Dermatology
Authors: Janagond Ajit B. , Inamadar Arun C.
Published: November 2021

Background and Aims:

Clinical photography is a vital component of patient care in dermatology. Casual sharing of images over social media is a common practice among the clinicians. We performed this study to assess the perception and behavior of dermatologists toward clinical photography.

Materials and Methods:

A questionnaire having 10 questions was prepared using an online survey platform and the link to it was shared in a dermatologists group using the WhatsApp application. Among questions, nine were multiple choice type while the tenth was open ended. Some of the questions allowed multiple responses and answering all the questions was not mandatory. Resultant data was analyzed using Chi-square test for categorical variables and unpaired t-test to compare quantitative variables.

Results:

A total of 119 dermatologists participated in the study. Most respondents used personal smartphone (72.9%, 86/118) for imaging followed by digital camera (27.9%, 33/118). Monitoring the disease process (83.9%, 99/118) and research publications (51.6%, 61/118) were the commonest reasons for photography. Except one all participants had shared images and most commonly in professional WhatsApp groups (86.3%, 101/117) and to personal WhatsApp number (31.6%, 37/117). Patient consent for photography was duly recorded by very few (14.4%, 17/118). More than half (52.3%, 56/107) responded monitoring of the disease as the single most important application of clinical photography in dermatology.

Conclusion:

Adequate awareness regarding appropriate usage and safekeeping of gadget meant for imaging and necessity of obtaining written consent for taking as well as sharing the images and secure storage of the images was found to be lacking.
Prolonged breastfeeding and protective effects against the development of allergic rhinitis: a systematic review and meta-analysis
Authors: Hoang M.P. , Samuthpongtorn J. , Seresirikachorn K. , Snidvongs K.
Published: November 2021

Background: There is insufficient evidence to confirm the protective effects of prolonged breastfeeding against the development of allergic rhinitis (AR). Methodology: A systematic review and meta-analysis was performed to assess the associations between prolonged breastfeeding and AR symptoms later in life. Comparisons were conducted between breastfeeding durations less than 6 months and 6 months or more and between less than 12 months and 12 months or more. Exclusive breastfeeding and nonexclusive breastfeeding were analysed separately. Outcomes were risks of AR development later in life. Results: Twenty-three observational studies (161,611 children, age 2-18 years, 51.50% male) were included. Two studies (9%) were with high quality. Both exclusive and nonexclusive prolonged breastfeeding (6 months or more) decreased the risk of AR. The long-term (12 months or more) nonexclusive breastfeeding lowered the likelihood of AR compared to the 12 months or fewer. The long-term exclusive breastfeeding did not show the same protective effect; however, this result was restricted to only one study. Conclusions: Exclusive breastfeeding and nonexclusive breastfeeding for 6 months or more may have protective effects against the development of AR up to 18 years of age. The findings should be interpreted with caution given the limitation of low-quality observational studies.
Nutritional changes induced by fungi on cowpea (Vigna unguiculata L. Walp) seeds
Authors: Iyanyi Nkechi Gloria , Ataga Anthony Eromosele
Published: November 2021

Seeds are usually infected by microorganisms and pests during storage, causing deterioration and reduction in the nutritive and market value of these seeds. In this study, the proximate composition of Vigna unguiculata seeds inoculated with different fungal organisms was determined to ascertain the level of deterioration caused by fungi on the seeds. The fungi used in the study were Botryodiplodia theobromae, Fusarium oxysporum, Rhizopus stolonifer and Aspergillus niger. There was a significant increase (p<0.05, 0.008) in the protein content of seeds inoculated with fungi. Fusarium oxysporum (29.45%) caused the highest increase in protein followed by Aspergillus niger (28.14%), Botryodiplodia theobromae (27.85%) and Rhizopus stolonifer (27.50%). The increase could be attributed to the proteineous content of the fungal mycelia. There was a significant increase (p<0.05, 0.005/0.014) in moisture and ash content of inoculated seeds respectively. Fusarium oxysporum caused the highest increase in ash (7.93) while Rhizopus stolonifer (5.4) caused the lowest increase. The increase in ash content is due to the presence of minerals like potassium and phosphorus in the mycelia of the fungi. There was a significant decrease (p<0.05, 0.019) in the carbohydrate, lipid, fibre and dry matter content of fungi-inoculated seeds when compared with the control. Fusarium oxysporum (36.6) caused the highest decrease while Rhizopus stolonifer (43.2) caused the lowest decrease in dry matter of inoculated seeds. Decrease in dry matter may be as a result of production of enzymes by these fungi.
Use of nailfold video capillaroscopy in polycythemia vera
Authors: Duygu Ersozlu Emine , Bakirci Sibel , Sunu Cenk , Ertürk Zeynep , Bilal Açıkgöz Seyyid , Tamer Ali
Published: November 2021

Objectives: In this study, we aimed to investigate capillary vessel diameters and structural changes of capillaries by using nailfold video capillaroscopy (NVC) in patients with polycythemia vera (PV).

Patients and Methods: This cross-sectional study included a total of 24 patients (19 males, 5 females; mean age: 59.8±12.9 years; range, 50.2 to 68 years) who were diagnosed with PV and 15 healthy controls (11 males, 4 females; mean age: 40.7±5.1 years; range, 36 to 44 years) between June 2016 and February 2017. Nailfold video capillaroscopy was performed by an experienced rheumatologist who was blinded to clinical data. The apical, arterial, and venous limb diameters of capillaries were measured and microvascular changes of capillaries were scored.

Results: When capillaries were evaluated in terms of morphological structures, giant capillary was detected in 67% of the patients with PV and 0% in the control group (p<0.05). The arterial, venous, and apical diameters of the capillaries were significantly higher in the patients with PV compared to the control group (p<0.001).

Conclusion: The presence of giant capillaries and the marked increase of arterial, venous, and apical diameters of capillaries seem to be related to PV. As it additionally plays an important role in diagnosis, prognosis, and treatment monitoring of certain diseases, capillaroscopy can be considered to be a promising microcirculation biomarker.
Inimigo encoberto e mortalidade: A gestão do COVID-19 em Atotonilco, México
Authors: Montalvo Vargas Ramos
Published: November 2021

O objetivo do trabalho é proporcionar uma aproximação sobre a gestão das informações oficiais do COVID-19, a respeito da realidade que vive a população de Atotonilco, pertencente ao município de Tlaxco que adquiriu a insígnia de cidade mágica em 2015 outorgada pela Secretaria de Turismo do Governo Federal do México. O método utilizado foi misto, foram utilizados dados públicos e relatórios de jornais do comportamento epidemiológico, foram realizadas entrevistas com sete pessoas da localidade com a variável da mortalidade; e, com a utilização de Sistemas de Informações Geográficas (SIG), foi mapeada a distribuição espacial dos óbitos. Dentre os principais resultados, constatou-se que nos níveis mundial, nacional, estadual e municipal, o número médio de óbitos por 1000 habitantes é de 0,08; 0,32; 0,43 e 0,25 respectivamente; enquanto em Atotonilco é 7,45 o que é explicado pela grande mobilidade para a Central de Abasto na Cidade do México. Diante desse infodêmico negativo que alimenta o medo, a desinformação, a manipulação e o manuseio duvidoso de dados, sugere-se um modelo de painéis de segurança comunitários para o local; entretanto é preciso responder, será que além do vírus, estamos diante de outro inimigo oculto?
Ornamental potential of the coastal plant Lapiedra martinezii Lag. (Amaryllidaceae): the role of its revalorization in xero-gardening and ex-situ conservation
Authors: Juan Vicedo Jorge , Laguna Emilio , Ríos Segundo , Casas José
Published: November 2021

Lapiedra martinezii Lag. (Amaryllidaceae) is an autumn-flowering geophyte that grows in coastal and sublittoral environments. The interests on this species has come out during the last decades due to its content in bioactive alkaloids and its conservational status. The aim of this work was to review the available information on L. martinezii and to assess whether it could be introduced as ornamental plant in xero-gardening. Therefore, the aesthetic traits were analyzed and compared to other cultivated and wild plants. Also, information on its ecological and propagation requirements were checked to discern whether it could be adapted under different production systems and culture conditions. In addition, other aspects were also analyzed to identify strengths and limitations of this species for its further revalorization as ornamental plant. The results obtained suggest that L. martinezii could be a good choice as foliage plant to grow it on gardens as an alpine bulb or pot plant. Moreover, it might be quite well adapted under different production and culture conditions in dry and semi-arid regions. The horticultural traits related to its germination and in vitro multiplication are interesting strengths to bear in mind for its industrial propagation and early domestication. Finally considered, the introduction in xero-gardening could also help in its ex-situ conservation. However, a more-in-depth research would be needed to finally introduce it in the ornamental plants’ market.
DRP1 Mediated Fission Has an Important Role in Alzheimer’s and Parkinson’s Diseases
Authors: Prieto Ruiz Jesús Ángel , Gómez - Reino López Jorge , Antón Canales Oscar , Ventura González Ignacio
Published: November 2021

Objectives - Our objectives are to perform a bibliometric analysis with which to highlight the relevance of Drp1 in the pathogenesis of AD and PD as a fundamental regulator of mitochondrial fusion and fission homeostasis, in addition to highlighting Drp1 as a possible therapeutic target in AD and PD.

Methods - We have carried out a bibliometric study based on a search in the PubMed database, the selected articles that are in the period from 01/01/2008 to 12/31/2019. Through an analysis of the data and a representation in graphs we show the relationship between Drp1 with AD and PD.

Results - The analyzed data show a slow but stable growth interest in the relationship of Drp1 with AD and PD. First, we analyze the number of publications per year that both the AD and PD remain stable over time, followed by the number of publications we are interested in observing the quantitative validity of these data, expressed in the average JCR per year and the number of citations of the articles, which show an interest in the role of Drp1 in AD and PD.

Conclusions - Our bibliometric analysis shows that the relationship of Drp1 with AD and PD is relevant, that it is currently interested and that they are applying Drp1 as a key protein in the pathogenesis of both diseases and, therefore, as a possible therapeutic target for treatment. of both pathologies.
Efecto de la actividad de agua y la temperatura sobre el crecimiento y la esporulación de Aspergillus niger P.E.L. van Tieghem
Authors: Sempere-Ferre Francisca , Santamarina M. P.
Published: November 2021

El efecto de la actividad de agua (0.85, 0.90, 0.95, 0.98, 0.995) sobre el crecimiento y la esporulación de Aspergillus niger fue estudiado a distintas temperaturas (15 y 25ºC). La máxima ratio de crecimiento de la especie se registró a una actividad de agua de 0.98, observándose desarrollo en todo el intervalo ensayado salvo a 0.85 y 15ºC. Además, se investigaron sus características morfológicas y culturales en las distintas condiciones de experimentación. A. niger esporuló en casi todas las actividades de agua y temperatura. Ambos factores y su interacción tuvieron un efecto significativo sobre el desarrollo de la especie.
Efecto del precultivo con sacarosa en la criopreservación por vitrificación de plántulas de Sideritis leucantha Cav. subsp. leucantha producidas in vitro
Authors: Juan Vicedo Jorge , Ramírez-Luna Jorge Eliseo , Piqueras Abel , Casas José Luis
Published: November 2021

Sideritis leucantha Cav. subsp. leucantha es un endemismo valenciano con uso medicinal que tiene diversos problemas de conservación. Por tanto, el objetivo principal de este trabajo fue probar el efecto de un tratamiento de precultivo para la posterior criopreservación de brotes apicales de esta especie. Los resultados mostraron que el precultivo con sacarosa 0.3 M durante 24 horas result en una mayor supervivencia de los explantes y regeneración in vitro después de tres tratamientos de vitrificación ensayados. Estos resultados sugieren que el acondicionamiento de los explantes puede mejorar la supervivencia de los explantes de S. leucantha subps. leucantha cultivados in vitro tras la criopreservación
PRODUCTIVIDAD Y ANÁLISIS QUÍMICO PROXIMAL DE Pleurotus spp. CRECIDOS SOBRE BAGAZO DE Agave salmiana COMO SUSTRATO ALTERNATIVO
Authors: España Rodríguez Montserrat , Hernández Domínguez Edna María , Velázquez De Lucio Brianda Susana , Villa García Matilde , Álvarez Cervantes Jorge
Published: November 2021

El bagazo de Agave salmiana es un subproducto de la elaboración de bebidas alcohólicas (pulque, mezcal), extracción de inulina o de agua miel, el cual puede aprovecharse para el cultivo de hongos comestibles. Con la hipótesis de que la característica química del bagazo de agave permite el crecimiento de Pleurotus spp. sin afectar valor nutricional; el objetivo de esta investigación fue estimar eficiencia biológica, tasa de productividad y obtener el análisis químico proximal de Pleurotus sp. y Pleurotus ostreatus crecidos sobre bagazo de Agave salmiana como sustrato alternativo al comercial. Para el estudio Pleurotus sp. se recuperó de crecimiento natural sobre A. salmiana y P. ostreatus de una cepa comercial; para el cultivo se utilizó bagazo del agave y paja de cebada como control. De los cuerpos fructíferos obtenidos se determinó la composición química proximal, eficiencia biológica y tasa productiva de ambos hongos, así como el análisis proximal del bagazo de agave antes y después del cultivo. Los datos se analizaron con la prueba de Student con probabilidad de error en p≤0.05. El hongo aislado de A. salmiana presentó características morfológicas propias del género Pleurotus. El bagazo de maguey pulquero presentó 0.52% de nitrógeno total y 3.28% de proteína cruda y estos valores aumentaron (0.59, 3.72%) después del cultivo. En Pleurotus sp. la eficiencia biológica y tasa productiva fue mayor (p≤0.05) en fibra de maguey (52.30%, 0.87% d-1); mientras P. ostreatus resultó más productivo (59.69%, 0.99% d-1) sobre paja de cebada. El análisis químico proximal de los hongos mostró valores favorables respecto a los valores de referencia del género Pleurotus; el contenido de proteína cruda de P. ostreatus fue 18.19% y 24.04% en Pleurotus sp. El bagazo de maguey pulquero mostró que posee características químicas que satisfacen y permiten el desarrollo del género Pleurotus, y es apto para su uso como sustrato alternativo.
EVALUACIÓN DEL PROCESO DE SECADO POR LECHO FLUIDIZADO SOBRE LOS ATRIBUTOS DE CALIDAD EN HOJAS DE ESTEVIA (Stevia rebaudiana)RIBUTOS DE CALIDAD EN HOJAS DE ESTEVIA (Stevia rebaudiana)
Authors: Noyola Altamirano Beatriz , Méndez Lagunas Lilia Leticia , Aquino González Laura Victoria , Rodríguez Ramírez Juan , Sandoval Torres Sadoth , Barriada Bernal Luis Gerardo
Published: November 2021

Las hojas de estevia (Stevia rebaudiana) son fuente de compuestos bioactivos benéficos para la salud humana; entre ellos destacan los glucósidos de esteviol. El valor comercial de las hojas deshidratadas de estevia se relaciona con su apariencia física y con la concentración de glucósidos. La hipótesis del estudio fue que la calidad de las hojas de estevia, con base en contenido de compuestos bioactivos presentes en las hojas puede ser visible y modificado por el secado. Para probarla, el objetivo fue evaluar el efecto de la temperatura, la velocidad de aire y la densidad de carga de hojas de estevia en un secador de lecho fluidizado no empacado y empacado sobre las características de color, concentración de glucósidos de esteviol (esteviósido y rebaudiósido A), concentración de compuestos fenólicos totales, concentración de flavonoides, y capacidad antioxidante. Las variables fisicoquímicas se evaluaron por medio de coordenadas CIEL*a*b*, cromatografía de líquidos fase reversa, métodos colorimétricos de Folin-Cicolteau, cloruro de aluminio y ensayo de inhibición de radicales libres DPPH*. El efecto de las variables de proceso se evaluó con un diseño de factorial completo con 24 combinaciones de factores y tres repeticiones de muestreo. La configuración de lecho fluidizado afectó (p≤0.05) la concentración de glucósidos de esteviol en el material foliar seco. En las dos configuraciones el contenido de glucósidos de esteviol aumentó entre 230-290% comparado con el material foliar fresco. Para la configuración de lecho no empacado, el retrogusto amargo (relación rebaudiósido A/esteviósido) fue mayor que el original evaluado en el material fresco. Todas las variables de proceso tuvieron influencia significativa en la concentración de polifenoles. La configuración con lecho empacado incrementó la concentración de compuestos fenólicos (p≤0.05) hasta 248%. En tanto que, con lecho no empacado disminuyó hasta un 17% (p≤0.05) en relación con el material fresco. La disminución en los tiempos de secado y el incremento de compuestos bioactivos (glucósidos de esteviol y compuestos antioxidantes) en la hoja de estevia, hacen de este método de secado una herramienta útil para el manejo y la preservación de materiales vegetales que contengan metabolitos secundarios de importancia económica.
GENETIC VARIABILITY IN Sechium spp. (Cucurbitaceae) EVALUATED WITH AFLP MARKERS
Authors: Iñiguez Luna María Isabel , Cadena Iñiguez Jorge , Cortés Cruz† Moisés , Morales Flores Francisco Javier , N. Watanabe Kazuo , Machida Hirano Ryoko , Soto Hernández Ramón Marcos , Avendaño Arrazate Carlos H.
Published: November 2021

There are few studies in Mexico aimed at evaluating the genetic variability of Sechium spp. Despite certain biological variants are reported with very high potential to develop antineoplastic supplements to treat public health conditions. Using the Amplified Fragment Length Polymorphism (AFLP) technique, the genetic variability of a sample of 95 accessions of three species of Sechium (S. edule, S. chinantlense, S. compositum) was evaluated, with leaf DNA from the Banco Nacional de Germoplasma de Sechium edule en Mexico. Four combinations of AFPL were applied (EcoRI + ACC/MseI + CAC, EcoRI + ACC/MseI + CAT, EcoRI + ACC/MseI + CGC, and EcoRI + ACC/MseI + CGG). DNA samples were classified into three groups based on the flavour of the fruit (sweet, neutral, bitter). An average of 47.91% polymorphism, 0.16 heterozygosity, 32.83 number of polymorphic bands, and a zero Wright fixation index (Fst) was obtained. The evidence showed that the domesticated accessions (sweet, neutral) were separated from the bitter-taste genotypes. A monophyletic tree was generated with the genetic distance matrix and the neighbour-joining methodology. Analyses showed S. edule as the root taxon, deriving S. compositum and S. chinantlense as subgroups, and suggesting that there is not enough differentiation to treat them as separate species. The evaluated sample showed that there is no apparent reproductive barrier for genetic cross breeding. Genotypes behaved as a complex with evolutive dynamism; that genetic complexity would allow the design of new variants.