bluuebunny/crossref_metadata_2025 huggingface dataset:
GAMBARAN PENGETAHUAN MASYARAKAT TENTANG BAHAYA VIRUS CORONA DIDESA KALI UPA KECAMATAN LOLODA UTARA
Authors: Sri Sero Leni , Asih Blandina Olivia , Nur Fitria Pipit
Published: May 2022

Background: The corona virus is a disease that causes the respiratory tract ranging from the common cold, difficulty breathing and even death.

Purpose: of this study was to identify a description of public knowledge about the dangers of covid-19 in Kailupa Village, North Loloda District.

Method: the study uses a quantitative method with a descriptive approach. This research will be carried out in Kailupa Village, North Loloda District in July-August 2020. The samples taken in the study are the people of Kailupa Village, North Loloda District who are 14-59 years old. The sampling technique uses Probility sampling technique with simple random sampling technique, sampling using the Slovin formula in order to get 100 respondents. The data obtained in this study were collected using a questionnaire distributed to the people of Kailupa Village, Loloda Utara District.

Results:analysis in this study used univariate data analysis. Based on the data from the questionnaire, the researcher found that the knowledge of the people of Kailupa Village was quite good and not good about the dangers of the corona virus.

Conclusion: Public knowledge about the dangers of the corona virus in Kailupa Village, North Loloda Subdistrict has sufficient and inadequate knowledge.
PERSEPSI MASYARAKAT TERHADAP PEMBANGUNAN JEMBATAN SEI BINGEI
Authors: Sitepu Heny Sri Dewi , Kusmanto Heri , Amin Muryanto
Published: May 2022

Facilities and infrastructure as an important instrument in the effort to do development on multi aspects of life. This study aims to see the public perception of the construction of the bridge Sei Bingei Village Berngam District Binjai Binjai Towns. Data collection techniques used in this study are in-depth interviews, observation, literature study and documentation. The result of the research shows that the construction of the sei bingei bridge is not followed by the improvement of the completeness of the public transportation infrastructure so that the existence of the Sei Bingei Bridge can not be utilized optimally for the mobilization rate of social life and the economy of the community.
DESKRIPSI POTENSI DAN STRATEGI PENGEMBANGAN PARIWISATA DI KOTA BERASTAGI KABUPATEN KARO
Authors: Erianto Edy
Published: May 2022

Karo regency has alot of tourism potential consist of marine tourism, religious tourism, culture tourism, ecotourism and others. The tourist destination have it’s own appeal for domestic or foreign tourists. The tourist visits increased every year.

This study aims to determine the potential and strategy for developing tourism in Karo District. This type of research is qualitative research with a descriptive approach. Research informants were determined purposively. The technique of collecting data was done by observation, interviews and documentation. Analysis data is was with data reduction, presentation of data, conclusion and data triangulation. The data are presented and analyzed in descriptively. The results shows that department of tourism Karo regency have strategy to develop the tourism. Development strategy used such as; Man, for maximize human resources quantity of department of tourism Karo regency, then departmen of tourism has cooperate with stakeholder such as community, agent, blogger, and establish tourism promotion agency for support the tourism marketing.
IMPLEMENTASI KEBIJAKAN KURIKULUM 2013 (STUDI PADA SEKOLAH MENENGAH PERTAMA NEGERI 7 PEMATANGSIANTAR)
Authors: Sinaga Jeremia Pratama , Sihombing Marlon
Published: May 2022

Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif dan objek penelitiannya adalah melibatkan unsur-unsur sekolah seperti Kepala Sekolah, Wakil Kepala Sekolah bidang Kurikulum dan guru-guru di SMPN 7 Pematangsiantar. Fokus penelitian ini untuk mengetahui dan menganalisa pelaksanaan Kebijakan Kurikulum 2013 di SMPN 7 Pematangsianar dengan menggunakan model yang digagas oleh George C. Edward III berupa komunikasi, sumber daya, disposisi dan struktur birokrasi yang berperan dalam pelaksanaan kebijakan. Data yang digunakan merupakan data verbal dari informasi responden tentang implementasi kebijakan kurikulum 2013 di SMPN 7 Pematangsiantar. Teknik pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Analisa data dalam penelitian ini meliputi tahap reduksi data, penyajian data dan verifikasi data atau penarikan kesimpulan. Hasil penelitian menunjukkan bahwa implementasi kebijakan kurikulum 2013 di SMPN 7 Pematangsiantar secara umum berjalan dengan baik namun belum optimal. Hingga berjalan di tahun ke tiga, dengan evaluasi-evaluasi yang dibuat tiap tahun membuat pelaksanaan kebijakan ini lebih optimal.
IMPOLITEESS STRATEGIES USED ON ONLINE COMMENTS IN THE LIPUTAN6.COM OF POLITICAL NEWS
Authors: Meidipa Lisa Fitri , Lubis Khairunnisah
Published: May 2022

This study investigates the impoliteness strategies in online comments in Liputan6.com. The objectives of this study are: 1) to investigate the types of impoliteness strategies used on online comments in website Liputan6.com, 2) to find out the dominant type of impoliteness strategies used on online comments in website Liputan6.com. This study was conducted by using   qualitative content analysis method. The data were taken from comments of internet users in five topics of political news in Idntimes.com. The finding showed that four of five types of impoliteness strategies are used on online comments in website Liputan6.com. They are: Bald on Record, Positive impoliteness, Negative Impoliteness, and Sarcasm or Mock politeness. The dominant types is negative impoliteness by used scorn or ridicules comments and invade the other's space with that comments and explicitly associate the other with a negative aspect.
ANALISIS FAKTOR PENYEBAB TINGGINYA TINGKAT GOLPUT MASYARAKAT PADA PEMILUKADA KABUPATEN BUNGO TAHUN 2011 DI KECAMATAN PASAR MUARA BUNGO
Authors: Harpinsyah Harpinsyah , Kusuma Halim Perdana
Published: May 2022

This research was conducted at Pasar Muara Bungo District. The location was chosen on purpose or "purposive". The location was chosen because it was included in 3 (three) Districts that had a high level of golput (white group) compared to other Districts in Bungo Regency, namely 4.817 voters or 10,5%. This study aims to analyze the factors that influence the high level of abstention from the community in the 2011 Pemilukada Bungo Regency in Pasar Muara Bungo District. The method in this research is quantitative with data taken from the Permanent Voters List (DPT) of the Bungo Regency Pemilukada in 2011. The results show that among the factors that cause low levels of community participation in post-conflict local elections are socio-economic factors, passive community participation and psychological and rational factors
KEGIATAN HUMAS MELALUI WEBSITE TERHADAP PEMBENTUKAN CITRA PEMERINTAH KABUPATEN ACEH BARAT
Authors: Elitear Julian , Humaizi Humaizi , Dayana Dayana
Published: May 2022

This study aims to analyze the information architecture, content,governance, website design, analyzing the image of West Aceh District Government,and to analyze how much the relationship of public relations activities through the website(website information architecture, website content, website governance, website design)towards the image formation of West Aceh District Government. Populationresearch is a website visitor acehbaratkab.go.id. Populationamounted to 261,943 people and by using Taro Yamane formula obtainedsample of 100 people. The technique of determining the sample using the methodpurposive sampling, and accidental sampling. Data collection of this studyusing questionnaires. The data collected is processed by usingcorrelation analysis to see the relationship of Public Relations Activities Through Websitewith the image of West Aceh District Government. The results foundthat the PR activities through the website of West Aceh which consists of architecturewebsite information shows good results, website content shows resultsthe less good, the website governance shows less good results, designthe website shows good results. The findings relate to the image of the Government of West Aceh of personality, reputation, value, corporate identity show average resultsnice.
IMPLEMENTASI KEBIJAKAN TENTANG SYARAT DAN TATA CARA PELAKSANAAN HAK WARGA BINAAN PEMASYARAKATAN PADA LEMBAGA PEMASYARAKATAN
Authors: Harpinsyah Harpinsyah , Arpani Arpani
Published: May 2022

The location of the research was carried out in the Class II B prison of Muara Bungo . This research took place for 1 month, from March 01 to March 30, 2021. The aim of the study was to determine the implementation of Government Regulation Number 32 of 1999 concerning the Terms and Procedures for the Implementation of the Rights of Correctional Inmates at the Class II B Correctional Institution Muara Bungo, to determine the factors obstacles in implementing Government Regulation Number 32 of 1999 concerning Terms and Procedures for the Implementation of the Rights of Correctional Inmates at the Class II B Correctional Institution Muara Bungo and To find out the efforts made in implementing Government Regulation Number 32 of 1999 concerning Terms and Procedures for the Implementation of Citizens' Rights Correctional Assistance at the Class II B Correctional Institution Muara Bungo. This study uses a qualitative method. The results showed that the implementation of Government Regulation Number 32 of 1999 concerning the Terms and Procedures for the Implementation of the Rights of Correctional Inmates, namely Education and coaching at the Class B Muara Bungo Prison includes: Religious Awareness Education, Physical and Spiritual Health Education, National Awareness Education, State and Awareness Law, Art Education. Educational and coaching activities carried out by the Class II B prison of Muara Bungo have been in accordance with Government regulation No. 32 of 1999 but in the implementation there are still some obstacles. Inhibiting factors in the implementation of Government Regulation No. 32 of 1999 Every form of education and development carried out almost certainly has obstacles, be it large or small scale. Obstacles that exist during the effort to fulfill the right to education and development of inmates in Lapas Class II B Muara Bungo are: The time and form of coaching for inmates is relatively short, Lack of Human Resources (HR), lack of facilities and infrastructure and lack of budget Education and coaching as well as the Fostered Citizens Factor itself. Efforts made in overcoming barriers to fostering inmates are using the Approach Method, the approach method used in overcoming the obstacles that exist in correctional institutions, increasing the interest of inmates, conducting training, expanding product marketing and tightening security surveillance.
IDEOLOGI NUBUWWAH DALAM PEMBANGUNAN WILAYAH MELALUI KEBIJAKAN DAN PERSPEKTIF POLITIK IBNU SINA
Authors: Nazri M , Mukti Abdul , Dahlan Zaini
Published: May 2022

A politics does not have some rich people who have the power to achieve authority.  Understanding Politics will be narrow if it is interpreted as a power conflict to gain position and authority.  Politics is the style of humans interacting to form social relations in order to give birth to an equitable and prosperous country, therefore politics belongs together.  The state will not be realized as a respectable country if there is no good interaction from the leader and his people.  Both of them practice what has been agreed upon together.  This article focuses on Ibn Sina's political thought as a social and political analysis found today, especially in Indonesia.  Ibn Sina's political ideas lead to nubuwwah as well as foreign political thoughts.  Thus, the State Leaders actually practice the values ​​of the Prophetic heritage in their souls.  Similarly, what is carried out by the community is to comply with the existing regulations in their territory, so that the realization of a country with noble character is realized.
First study of Genetic diversity in watermelon (Citrullus lanatus) germplasm collected from Southern Tunisia using RAPD markers
Authors: Elbekkay Mokhtar , Hamza Hammadi , Bekri Tozer , Haddad Mansour , Ferchichi Ali
Published: May 2022

The genetic diversity in local Tunisian watermelon (Citrullus lanatus) was studied using RAPD markers. Eight watermelon cultivars originating from south of Tunisia and belong to four populations were analysed and compared to two commercial varieties (Giza and Sugar-baby) widely produced in this area. Five of nine RAPD primers generated a total of 86 reproducible bands, 85 of which were polymorphic (98.4%). Cluster analysis of the accessions considered in this study employing RAPD data indicated that commercial varieties are significantly different of all the local cultivars. The relationships among the local cultivars (four populations) showed that Medenine population and the most genotypes of Benguerdane population were grouped together and significantly different from Kebili population. The AMOVA showed significant differentiation between populations (27%). In addition, the data showed clusters according to some fruit characteristics such as fruit shape and fruit weight. This proved that RAPD markers are useful for germplasm discrimination as well as for investigation of patterns of variation in watermelon.
Biotic potential of an exotic date palm pest specie: Oryctes agamemnon (Coleoptera: Scarabaeidae)
Authors: Ehsine M’hammed , Belkadhi Mohamed Sadok , Chaieb Mohamed
Published: May 2022

In Tunisia, particularly in southern regions, the culture of date palms plays an important role, both at socioeconomic and ecological levels. In spite of its importance, this agro-system is still threatened by many species of insects and diseases. Among these phytosanitary problems figure the exotic pest Oryctes agamemnon. This insect causes severe damage on palm tree mainly on the collar and the root system. The aim of this work is to study some parameters of the biotic potential of the insect.  A number of ten couples were used in this survey. Follow-up of the experiment under the following conditions (Relative humidity = 40 +/- 6%, Temperature = 28 ° C +/- 2 ° C and a photoperiod: 16/8) allowed to study the reproductive potential, the larval survival rate and the adult lifetime.  The follow-up of the experiment shows that the average pre-oviposition period and the average post-oviposition period are 25.3 ± 9.85 and 7.3 ± 5.39 days, respectively. The developmental cycle comprises, the egg, 3 larval stages L1, L2 and L3, prenymph and nymph respectively lasted 13,742 ± 2,011 days, 26,591 ± 3,142 days, 43,361 ± 3,237 days, 137,047 ± 6,132 days, 7,487 ± 0,909 days and 21,390 ± 2,655 days. Survival rates for the various stages ranged from 83.631 to 93.886%. Adults lived on average 55.18 days for males and 60 days for females. The average number of eggs laid per female was 28.7 ± 17.13 with an average fertility rate of 81.184%.
Mineral fruit composition variation alongside Phoenix dactylifera L. cultivars dependently on geographical origin and agronomic traits.
Authors: Hamza Hammadi , Jarray Naceur , Yahya Leila , Ferchichi Ali
Published: May 2022

Date palm gives fruits that make a significant human dietetic through great amounts of different sugars supplement and of minerals. Water, ash and six minerals contents were investigated in dates of 131 individual trees. The geographical effect in mineral content was carried out on tow cultivars, Deglet nour and Alig. New oases of Jerid region, compared to other origins, gave date of Deglet nour with the highest levels of the studied parameters except for the ash and the Calcium contents which were stable between oases. However, old oasis of Jerid region had fruit Alig with the upper levels in phosphorus (0.1 g/100g), sodium (54.76 ppm), magnesium (0.05 g/100g) and iron (0.77 mg/100g); but the lowest in total mineral content (1.75 g/100g) and manganese (0.14 mg/100g). The effect of agronomic traits (maturity period and fruit consistency) was studied basing on 38 different cultivars. Concerning the maturity period, fruits of early ripening cultivars exhibited an elevated concentration in iron (0.87 mg/100g) and calcium (0.024 g/100g) in comparison with those of later maturity cultivars which had the highest ash percent (1.59 g/100g). For the fruit consistency, soft fruits showed the greater Iron content (0.84 mg/100g) but the dry ones exhibited the highest potassium content (0.57 g/100g). These results proposed to consumers that they have to consider the provenance, the fruit consistency and the maturity period which looks as a good indicator for mineral content.
Åtråvärda samer: om reseberättelser som affektiv resurs i tidig ursprungsturism
Authors: Westberg Gustav , Idevall Hagren Karin
Published: May 2022

Sedan massturismens födelse har åtrån efter autentiska upplevelser projicerats på samisk kultur. Med ett fokus på hur den tidiga ursprungs-turismens sakprosagenrer etablerar det samiska som något åtråvärt att uppleva för turister, blottlägger denna artikel hur turister positioneras känslomässigt i reseberättelser från Sápmi, publicerade i Svenska Turistföreningens årsskrift 1886–1914. Artikeln ramas in som en affektiv diskursanalys och undersöker hur reseberättelserna skildrar mötet mellan turister och samer i termer av aktantroller, och hur den narrativa strukturen positionerar läsaren känslomässigt. Resultatet visar hur den föreställda turistens åtrå efter samer utgör en blandning av lust, attraktion, äckel och välbefinnande. Artikeln argumenterar att dessa affektiva positioner har sin klangbotten i koloniala och rasbiologiska ideal. Avslutningsvis uppmanar artikeln till fortsatta affektiva diskursanalyser av ursprungsturismens sakprosatexter, med ett särskilt fokus på hur turister och samer positioneras genom ambivalenta och motstridiga känslor.
Wunderwaffe Interdisziplinarität
Authors: Meissner Jens O. , Doerk Michael
Published: May 2022

Das Arbeiten über Grenzen hinweg gilt als Quelle der Kreativität. Doch sind viele Unternehmen hervorragend darin, Interdisziplinarität zu zerstören. Auf fünf Killerkriterien gilt es besonders zu achten.
Pesticides and Sunflower Breeding
Authors: Hristova-Cherbadzhi Miroslava
Published: May 2022

The amount and quality of yields depend on the successful protection of crops from diseases, pests, weeds, and abiotic factors. The sunflower is a plant in which most diseases and pests are overcome genetically. The chemical method is also used in the production of sunflower, but it is important to say that there are still no genetically modified (GM) sunflowers on the market. By applying the classical breeding methods, new sunflower elite inbreed B lines that are resistant to two classes of herbicides (imidazolinones and sulfonylureas) were received. The aim of this study is to summarize the knowledge of pesticides and their use, as well as the breeding methods and resistance to herbicides in the sunflower.
The Effect of Learning Conditions on Collocation Gains: A Case Study of Task-based Dictionary Use Instruction
Authors: Chen Yuzhen
Published: May 2022

To examine the effect of learning conditions on collocation gains, 88 Chinese EFL students were assigned randomly to one of three different learning conditions, i.e. dictionary use with prior instruction, dictionary use without training, or explicit collocation teaching. They were asked to fill in the missing verb in ten V + N target collocations embedded in sentences. A screen recorder was used to keep track of the students' lookup behaviour in the two conditions involving dictionary use such as every input of the searched word, every move and click of the mouse, every step of collocation search and the time length of dictionary consultation. After completion of the assignment all the students were given corrective feedback to the collocation task and marked their corrections on the test paper. Two weeks later, an unexpected retention test was administered. The study showed that dictionary use following a five-step training session reaped significantly more collocation gains than dictionary use without prior instruction and explicit collocation teaching. Compared with those who used the dictionary without prior training, the students with prior dictionary instruction employed more effective strategies concerning the selection of lookup words and the location and identification of collocation information. They took a more conscientious approach to dictionary use and retrieved more correct target verbs. Apart from lending new support to the continuous appeal for a position of dictionary use instruction in the EFL pedagogy, the study also provides a detailed demonstration of task-based dictionary training applicable to classroom practice.
Genetic Cassettes Profiling of Class I Integron and Antimicrobial Susceptibility Profiles Among Pseudomonas aeruginosa Isolates Collected from Patients in North of Iran
Authors: Ebrahimi-Shahabi Reyhane , Ferdosi-Shahandashti Elaheh , Sabbagh Parisa
Published: May 2022

Background: Pseudomonas aeruginosa is an opportunistic nosocomial bacterium, especially in infection wards and among patients with burns. The present study addressed the molecular investigation of the gene cassettes of Class I integrin (intI) and its relationship with multiple drug resistance in clinical samples of P. aeruginosa isolated from Babol hospitals in north of Iran. Objectives: This study aimed to detect the frequency of intI and gene cassettes in the clinical isolates of P. aeruginosa. Methods: In this study, from 75 clinical samples, 30 strains were identified using specific biochemical methods. After determining antibiotic susceptibility using disk diffusion and agar dilution, the frequency of the intI gene and its gene cassettes were determined using the polymerase chain reaction (PCR) method. Results: The highest resistance rate was observed for cefotaxime, ampicillin, and nitrofurantoin using disk diffusion and agar dilution methods. The molecular analyses revealed that 60% of the isolates had the intI genes. The frequency of the aadB, dfrA1, and bla-OXA30 genes were 61, 66, and 33%, respectively. Conclusions: The high resistance of Pseudomonas isolates is due to the presence of intI and its gene cassettes. Considering their high resistance to cefotaxime, gentamicin, ampicillin, and imipenem in hospitals, selecting appropriate drugs or generally changing the treatment course for patients is possible to prevent the spread of resistance inducing genes and the development of nosocomial infections.
Margarita M. Balmaceda: Russian Energy Chains: The Remaking of Technopolitics from Siberia to Ukraine to the European Union
Authors: Jirušek Martin
Published: May 2022

Margarita M. Balmaceda: RUSSIAN ENERGY CHAINS: THE REMAKING OF TECHNOPOLITICS FROM SIBERIA TO UKRAINE TO THE EUROPEAN UNION. New York: Columbia University Press. 2021. 421 pages.
Analysis of Methods to Reduce Jogging Injuries from the Perspective of Risk Cognition
Authors: Hu Degang , Zhang Linteng , Zhang Wulong
Published: May 2022

Objectives: Injuries are common events that impair the function of joggers; it is important to take effective measures to reduce the incidence of jogging injuries to maximize its benefits. Methods: We collected questionnaires from 3468 Chinese exercisers using a stratified
random sampling method. We analyzed these data using AMOS 22.0 (IBM) and SPSS 26.0 (IBM). Results: We constructed a relationship model of jogging risk cognition, jogging risk behaviors, and jogging injury incidence, and the indicators fit well. The path coefficient between jogging risk
cognition and jogging risk behaviors of joggers was -0.64; the path coefficient between jogging risk behaviors and jogging injuries incidence was 0.44; and the path coefficient between jogging risk cognition and jogging injuries incidence was -0.23. Conclusions: The higher the level
of jogging risk cognition of joggers, the lower their jogging risk behaviors, leading to a lower incidence of jogging injuries. Based on the generally low level of jogging risk cognition of joggers, the construction of a jogging risk cognitive education system that can be integrated into universities,
middle schools and primary schools, as well as family, school and society, is conducive to comprehensively improve the level of jogging risk cognition of joggers.
The World Set Free
Authors: Wells H. G.
Published: May 2022

In a novel written on the eve of World War I, H. G. Wells imagines a war “to end all wars” that begins in atomic apocalypse but ends in an enlightened utopia.

Writing in 1913, on the eve of World War I's mass slaughter and long before World War II's mushroom cloud finale, H. G. Wells imagined a war that begins in atomic apocalypse but ends in a utopia of enlightened world government. Set in the 1950s, Wells's neglected novel The World Set Free describes a conflict so horrific that it actually is the war that ends war.

Wells—the first to imagine a “uranium-based bomb”—offers a prescient description of atomic warfare that renders cities unlivable for years: “Whole blocks of buildings were alight and burning fiercely, the trembling, ragged flames looking pale and ghastly and attenuated in comparison with the full-bodied crimson glare beyond.” Drawing on discoveries by physicists and chemists of the time, Wells foresees both a world powered by clean, plentiful atomic energy—and the destructive force of the neutron chain reaction.

With a cast of characters including Marcus Karenin, the moral center of the narrative; Firmin, a proto-Brexiteer; and Egbert, the visionary young British monarch, Wells dramatizes a world struggling for sanity. Wells's supposedly happy ending—a planetary government presided over by European men—may not appeal to contemporary readers, but his anguish at the world's self-destructive tendencies will strike a chord.

Sarah Cole is the author of Inventing Tomorrow: H.G. Wells and The Twentieth Century (2019). The Parr Professor of English and Comparative Literature and Dean of Humanities at Columbia University, she is the cofounder of the NYNJ Modernism Seminar and founder of the Humanities War and Peace Initiative at Columbia. She is also the author of Modernism, Male Friendship, and the First World War (2003) and At the Violet Hour: Modernism and Violence in England and Ireland (2012).

Joshua Glenn, who was the first to describe the years 1900–1935 as science fiction's “Radium Age,” has helped popularize stories from the era for over a decade now. A former Boston Globe staffer and publisher of the indie intellectual journal Hermenaut, he is coauthor of The Idler's Glossary (2008), Significant Objects (2012), and the family activities guide UNBORED (2012). He is also cofounder of the brand consultancy Semiovox; and he publishes the blog HiLobrow.
The Secrets of Words
Authors: Chomsky Noam , Moro Andrea
Published: May 2022

Two distinguished linguists on language, the history of science, misplaced euphoria, surprising facts, and potentially permanent mysteries.

In The Secrets of Words, influential linguist Noam Chomsky and his longtime colleague Andrea Moro have a wide-ranging conversation, touching on such topics as language and linguistics, the history of science, and the relation between language and the brain. Moro draws Chomsky out on today's misplaced euphoria about artificial intelligence (Chomsky sees “lots of hype and propaganda” coming from Silicon Valley), the study of the brain (Chomsky points out that findings from brain studies in the 1950s never made it into that era's psychology), and language acquisition by children. Chomsky in turn invites Moro to describe his own experiments, which proved that there exist impossible languages for the brain, languages that show surprising properties and reveal unexpected secrets of the human mind.

Chomsky once said, “It is important to learn to be surprised by simple facts”—“an expression of yours that has represented a fundamental turning point in my own personal life,” says Moro—and this is something of a theme in their conversation. Another theme is that not everything can be known; there may be permanent mysteries, about language and other matters. Not all words will give up their secrets.
METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis
Authors: Li Enjie , Xia Mingyue , Du Yu , Long Kaili , Ji Feng , Pan Feiyan , He Lingfeng , Hu Zhigang , Guo Zhigang
Published: May 2022

Methyltransferase-like 3 (METTL3) and N6-methyladenosine (m6A) are involved in many types of biological and pathological processes, including DNA repair. However, the function and mechanism of METTL3 in DNA repair and chemotherapeutic response remain largely unknown. In present study, we identified that METTL3 participates in the regulation of homologous recombination repair (HR), which further influences chemotherapeutic response in both MCF-7 and MDA-MB-231 breast cancer (BC) cells. Knockdown of METTL3 sensitized these BC cells to Adriamycin (ADR; also named as doxorubicin) treatment and increased accumulation of DNA damage. Mechanically, we demonstrated that inhibition of METTL3 impaired HR efficiency and increased ADR-induced DNA damage by regulating m6A modification of EGF/RAD51 axis. METTL3 promoted EGF expression through m6A modification, which further upregulated RAD51 expression, resulting in enhanced HR activity. We further demonstrated that the m6A ‘reader,’ YTHDC1, bound to the m6A modified EGF transcript and promoted EGF synthesis, which enhanced HR and cell survival during ADR treatment in BC. Our findings reveal a pivotal mechanism of METTL3-mediated HR and chemotherapeutic drug response, which may contribute to cancer therapy.
Welcome to the lab
Authors: Andreev Andrey , Komatsu Valerie , Almiron Paula , Rose Kasey , Hughes Alexandria , Lee Maurice Y
Published: May 2022

Having a formal onboarding procedure for new lab members can lead to a happier and more productive working environment.
Reassessment of Faxinalipterus minimus, a purported Triassic pterosaur from southern Brazil with the description of a new taxon
Authors: Kellner Alexander W.A. , Holgado Borja , Grillo Orlando , Pretto Flávio Augusto , Kerber Leonardo , Pinheiro Felipe Lima , Soares Marina Bento , Schultz Cesar Leandro , Lopes Ricardo Tadeu , Araújo Olga , Müller Rodrigo Temp
Published: May 2022

Faxinalipterus minimus was originally described as a purported pterosaur from the Late Triassic (early Norian) Caturrita Formation of southern Brazil. Its holotype comprises fragmentary postcranial elements, whereas a partial maxilla was referred to the species. The assignment of Faxinalipterus minimus to Pterosauria has been questioned by some studies, but the specimen has never been accessed in detail after its original description. Here we provide a reassessment of Faxinalipterus minimus after additional mechanical preparation of the holotype. Our interpretations on the identity of several bones differ from those of the original description, and we found no support favoring pterosaur affinities for the taxon. The maxilla previously referred to Faxinalipterus minimus is disassociated from this taxon and referred to a new putative pterosauromorph described here from a partial skull and fragmentary postcranial elements. Maehary bonapartei gen. et sp. nov. comes from the same fossiliferous site that yielded Faxinalipterus minimus, but the lack of overlapping bones hampers comparisons between the two taxa. Our phylogenetic analysis places Faxinalipterus minimus within Lagerpetidae and Maehary bonapartei gen. et sp. nov. as the earliest-diverging member of Pterosauromorpha. Furthermore, the peculiar morphology of the new taxon reveals a new dental morphotype for archosaurs, characterized by conical, unserrated crowns, with a pair of apicobasally oriented grooves. These two enigmatic archosaurs expand our knowledge on the Caturrita Formation fauna and reinforce the importance of its beds on the understanding of Late Triassic ecosystems.
Integrated lipidomics and RNA sequencing analysis reveal novel changes during 3T3-L1 cell adipogenesis
Authors: Pei Yangli , Song Yuxin , Wang Bingyuan , Lin Chenghong , Yang Ying , Li Hua , Feng Zheng
Published: May 2022

After adipogenic differentiation, key regulators of adipogenesis are stimulated and cells begin to accumulate lipids. To identify specific changes in lipid composition and gene expression patterns during 3T3-L1 cell adipogenesis, we carried out lipidomics and RNA sequencing analysis of undifferentiated and differentiated 3T3-L1 cells. The analysis revealed significant changes in lipid content and gene expression patterns during adipogenesis. Slc2a4 was up-regulated, which may enhance glucose transport; Gpat3, Agpat2, Lipin1 and Dgat were also up-regulated, potentially to enrich intracellular triacylglycerol (TG). Increased expression levels of Pnpla2, Lipe, Acsl1 and Lpl likely increase intracellular free fatty acids, which can then be used for subsequent synthesis of other lipids, such as sphingomyelin (SM) and ceramide (Cer). Enriched intracellular diacylglycerol (DG) can also provide more raw materials for the synthesis of phosphatidylinositol (PI), phosphatidylcholine (PC), phosphatidylethanolamine (PE), ether-PE, and ether-PC, whereas high expression of Pla3 may enhance the formation of lysophophatidylcholine (LPC) and lysophosphatidylethanolamine (LPE). Therefore, in the process of adipogenesis of 3T3-L1 cells, a series of genes are activated, resulting in large changes in the contents of various lipid metabolites in the cells, especially TG, DG, SM, Cer, PI, PC, PE, etherPE, etherPC, LPC and LPE. These findings provide a theoretical basis for our understanding the pathophysiology of obesity.
Analysis of Thermal Characteristics and Electrical Signal Using a Damaged Multi-outlet
Authors: Oh Buyeol , Park Jongyoung , Lee JaeHun , Jeon Kyunam , Choi Donmook
Published: May 2022

Recently, the use of multi-outlets has been increasing owing to the increased use of electrical appliances in households. The majority of users do not replace multi-outlets for several months or even years after purchase. Moreover, with the intention to save energy and prevent fire, users frequently unplug electrical appliances from multi-outlets, which may cause structural defects. Owing to a poor connection between the multi-outlet and plug, there is a risk of generating local heat, which may lead to fire. Therefore, in this study, a damaged multi-outlet with structural defects owing to long-term use is secured through repeated tests, and the risk of fire is determined based on its thermal characteristics and electrical current generated during use. It was confirmed that the temperature of the main switch was higher than that of the plug connection, and the damaged multi-outlet temperature was up to 2.4-fold higher than normal.
A Study on the Compositional Change of Steel Sheet According to Heating Temperature Using Portable XRF
Authors: Park Sang-Min , Kim Si-Kuk
Published: May 2022

This paper is a study on the compositional change of steel sheet according to the heating temperature using portable XRF. Color coating galvanized iron (CCGI), galvanized iron (GI), galvalume steel (GL), and electrolytic galvanized iron (EGI) often used in prefabricated buildings and interior design are selected as test samples, and the steel sheet is heated using a sand burner for 1800 s. According to the method, the compositional change of the steel sheet was measured and analyzed. As a result of the experiment, in the case of samples oxidized for 1 day after non-watering, the components with low melting points such as Zn and Al decreased according to the heating temperature of the steel sheet, and therefore the components of Fe with relatively high melting points increased high. In the case of the sample oxidized for 7 days after watering, the steel sheet damaged by the heating temperature reacted with water and the Fe component was measured to be higher. The possibility of predicting the heating temperature of the steel sheet through the change of the composition ratio of constituent elements was confirmed when portable XRF was used for fire investigation.
La irrupción en la ciudad prohibida de la historiografía
Authors: Urrutia Leiva Marie Juliette
Published: May 2022

Sobre: Canales, Pedro (2016). Zuamgenolu. Pueblo Mapuche en contexto de Estado nacional chileno, siglos XIX -XXI, Santiago de Chile, Editorial Universidad Santiago de Chile.Zuamgenolu. Pueblo Mapuche en contexto de Estado nacional chileno, siglos XIX -XXI es una compilación que reúne las reflexiones e investigaciones de cientistas sociales mapuche y no mapuche.
De madera y hormigón: hábitat residencial y habitar de migrantes latinoamericanos en la ciudad de Santiago
Authors: Palma Rojas Cristóbal Sebastián
Published: May 2022

En base a dos experiencias etnográficas, una en un campamento (asentamiento informal) ubicado en el extremo norte del Gran Santiago y otra, aún en curso, en zonas de verticalización residencial en el centro de la comuna de Santiago, el presente artículo discute sobre la influencia de las materialidades y espacialidades de la vivienda en la configuración del habitar de migrantes latinoamericanos en la Región Metropolitana. Se concluye que el hábitat en campamentos, cuya espacialidad y materialidad son de orden flexible y en permanente construcción, permite formas de apropiación espacial, de tipo simbólico y material, conforme se procede a la edificación y mejora de la vivienda, mientras que el hábitat en zonas de verticalización residencial cuya materialidad es rígida y se encuentra pre-definida, restringe de manera sustantiva las posibilidades de apropiación espacial a nivel material. Aun así, en la intimidad de la vivienda y a nivel simbólico y afectivo se producen formas de domesticación del espacio residencial que resultan modeladas por sus usuarios migrantes.
Precariedad, trabajo y reproducción: el trabajo de las mujeres en el sector exportador de uva en Chile y Brasil
Authors: Cerda Becker Claudia , Silva de Almeida Camilla , Cavalcanti Barbosa Josefa Salete
Published: May 2022

La expansión del agronegocio de exportación en Latinoamérica ha ido acompañado de una creciente femeinización de la fuerza de trabajo. No obstante, las mujeres han sido incorporadas en condiciones poco favorables, ocupando empleos de baja calificación, bajos ingresos y temporales. El presente artículo propone investigar la precariedad de las condiciones de trabajo y de vida de las mujeres que trabajan como asalariadas en el sector de exportación de uva en el Valle San Francisco (Brasil) y en el Valle de Elqui/Limarí (Chile), proponiendo un análisis que integra tanto la esfera de la producción como de la reproducción. Esto con la finalidad de identificar las interconexiones existentes entre ambos ámbitos así como los principales mecanismos de extracción de plusvalor y de externalización de los costos a los hogares, implementados por las empresas.
Raza y género en el marco de la diferencia ontológica colonial
Authors: Losada Cubillos Jhon Jairo
Published: May 2022

En los últimos años el pensamiento decolonial se ha constituido en un campo de reflexión teórica y de activismo político que busca, por un lado, visibilizar las formas en las que se sigue reproduciendo el poder colonial y, por otro lado, proveer herramientas para contribuir a fisurar las condiciones de dominación heredadas del hecho colonial. Este artículo tiene por objetivo situar las categorías de raza y género en el marco del pensamiento decolonial, como categorías fundamentales para problematizar y analizar la operacionalidad la dimensión ontológica de la colonialidad. En este sentido, recurre a autores y autoras de la tradición de pensamiento crítico afrocaribeño, así como del feminismo decolonial. Para esto, se discute con la categoría de diferencia ontológica colonial, como un aporte para continuar exteriorizando la naturaleza del orden colonial de poder y para ahondar en la comprensión en la forma cómo la colonialidad opera.
Un problema no es sólo un problema. Posiciones, hermenéuticas y políticas públicas relativas a la salud de las abejas
Authors: Folguera Guillermo
Published: May 2022

En diferentes lugares del mundo se discute acerca de la salud de las abejas y sus posibles causas. Argentina, uno de los principales productores de miel del mundo, inevitablemente ubica a esta problemática en un lugar central. En este trabajo indagaremos los modos de conceptualizar el problema y las hermenéuticas que le subyacen a diferentes agentes respecto a la salud de las abejas en Argentina. Con este fin, se realizará un análisis del vínculo entre posiciones y hermenéuticas de apicultores, Bayer, científicos de las áreas de la Toxicología y Biología del Comportamiento y funcionarios de diferentes áreas de SENASA, órgano de control del Estado argentino. Entre las conclusiones principales se reconoce: i) el acercamiento de las posiciones y hermenéuticas del Estado argentino y Bayer propio de un escenario neoliberal, ii) el modo en el que la Toxicología (área de mayor injerencia en la problemática) minimiza los riesgos ambientales respecto a la Biología del Comportamiento y iii) los numerosos procesos de simplificación que se reconocen en la toma de decisiones de la política pública en Argentina en los últimos años.
Las paradojas del trabajo actoral en teatro independiente. Un estudio comparativo de las representaciones sociales sobre teatro independiente de actores y actrices de La Plata entre los orígenes y la actualidad
Authors: Diaz Juliana
Published: May 2022

El objetivo del artículo es indagar las rupturas y continuidades de ladefinición de teatro independiente en sus orígenes (primeras décadas del siglo pasado) en Buenos Aires y particularmente en la ciudad de La Plata, respecto a las representaciones más recientes que formula el colectivo de actores y actrices de teatro independiente en la ciudad. En este artículo, comprendemos a las representaciones sociales como modos de significar las interpretaciones que los sujetos hacen de su entorno y a partir de las cuales logran comunicarse (Castorina et al., 2010). Este concepto se explica en vinculación con la estructura social y los habitus del campo incorporados (Bourdieu, 2007) y se caracterizan por ser sistemas indeterminados y abiertos (Longo, 2004). En relación con el mundo del trabajo, las representaciones sociales son “objeto de luchas tanto colectivas entre grupos sociales, como individuales entre atribuciones y apropiaciones de clasificaciones por parte del sujeto” (Longo, 2004, p. 5).Para ello, hemos llevado a cabo un análisis documental de distintos/as autores/as que han abordado los orígenes del teatro independiente en Buenos Aires como en La Plata. Además, realizamos veinte entrevistas en profundidad a actores y actrices residentes en la ciudad de La Plata, observaciones participantes en charlas, asambleas y reuniones que agrupan a distintos actores y actrices de teatro independiente y el proceso de ensayos y funciones de dos elencos del circuito independiente en La Plata. También, realizamos un total de ochenta y nueve encuestas de manera virtual dirigida a actores y actrices de la misma ciudad. Para su análisis, hemos puesto en diálogo los datos construidos desde una perspectiva cualitativa a partir de técnicas e instrumentos propios de la metodología cualitativa como cuantitativa. Para el procesamiento de datos, sehan utilizado los softwares Statistical Package for the Social Sciences (SPSS) y Atlas/ti.
Tácticas y estrategias de mujeres trabajadoras del sector servicios en Chile frente al conflicto: participación sindical, empleo y cuidados
Authors: Arteaga Catalina , Andrade de la Horra Valentina , Jiménez Vergara Ariel , Fuentes Landaeta Javiera Marina
Published: May 2022

El presente artículo aborda el conflicto de la participación sindical, empleo y trabajo de cuidados no remunerado, de trabajadoras de dos gremios del sector servicios en Chile. Dicho análisis se lleva a cabo en el contexto del aumento de la sindicalización femenina en el país, indagando en las complejidades y conflictos de la responsabilidad conjunta de actividades de cuidados no remunerados, empleo y participación sindical, así como en las estrategias quelas mujeres desarrollan para enfrentarlas. El trabajo aporta en una dirección distinta de las escasas investigaciones nacionales actuales acerca de la participación sindical femenina, que ponen el acento en su exclusión y marginación.Para ello se llevan a cabo entrevistas semiestructuradas y grupales, a mujeres sindicalistas de distintas edades de la Región Metropolitana. El trabajo muestra el desarrollo de tácticas y estrategias de resistencia para enfrentar el conflicto por parte de las mujeres en los tres ámbitos señalados, lo que incide en el posicionamiento en el ámbito sindical, acompañado de reordenamientos en el ámbito doméstico y un proceso de creciente empoderamiento.
Inserción laboral en actividades por cuenta propia. Migrantes wixaritari y mazahuas en Aguascalientes, México, 1960-2020
Authors: Rodríguez Herrera Jorge Alberto
Published: May 2022

Se trata de un estudio de corte cualitativo apoyado en la etnografía, en el que se contrastan dos maneras distintas de poner en circulación los recursos socioculturales que han permitido a indígenas migrantes insertarse en actividades comerciales por cuenta propia a partir de la década de 1960 en el estado de Aguascalientes, México. Se constata que dichas actividades han sido iniciadas, sostenidas y reproducidas por los wixaritari y mazahuas gracias a las relaciones de paisanaje, parentesco, amistad y compadrazgo, basadas en la confianza, los tratos flexibles y el mantenimiento de relaciones con sus comunidades de origen, así como un despliegue diferenciado de sus atributos identitarios.
Mecanismos de control de la plataforma Uber sobre sus conductores asociados en la Región Metropolitana de Chile
Authors: Vallejos Rivero Osvaldo
Published: May 2022

En el presente artículo se describen y analizan los principales mecanismos de control implementados por la plataforma Uber en el proceso de trabajo de sus conductores asociados en la Región Metropolitana de Chile. La información fue producida a través de 12 entrevistas realizadas a conductores de Uber residentes en la Región Metropolitana entre septiembre de 2019 y febrero de 2020, analizadas a través de un análisis cualitativo de contenido con el software Atlas ti7. El marco analítico utilizado fue tomado principalmente de la denominada teoría del proceso de trabajo, incorporando además ciertas discusiones actuales sobre nuevas formas de control elaboradas específicamente para el contexto del trabajo en plataformas digitales. Los principales resultados muestran una combinación entre elementos de control persistentes a lo largo del tiempo y elementos novedosos incorporados en los últimos años, específicamente a través de una introducción de mayor eficacia a métodos de control antiguos gracias a las nuevas tecnologías, haciendo que tanto las formas nuevas como antiguas de control sean más instantáneas, opacas y abarcadoras. Con todo, se observa una predominancia de aquellos mecanismos de control asociados al control algorítmico y a la estrategia de autonomía responsable.