bluuebunny/crossref_metadata_2025 huggingface dataset:
Triptofán-származékok, mint lehetséges biomarkerek és terápiás célpontok egyes kardiovaszkuláris megbetegedésekben
Authors: Nógrádi-Halmi Dóra , Erdélyi-Furka Barbara , Gáspár Renáta , Csont Tamás
Published: November 2023

A gyulladásos folyamatok kiemelkedő szereppel bírnak a vezető halálokok közé sorolható koszorúér-betegségek patomechanizmusában és progressziójában. Ismert, hogy az ezen folyamatok során felszabaduló proinflammatorikus molekulák képesek elősegíteni a triptofán-aminosav kinurenin-útvonalon történő lebomlását. Ez számos immunmodulátor kinurenin-metabolit felszabadulását teszi lehetővé, amelyek között egyaránt szerepelnek jótékony, valamint káros hatással bíró vegyületek. Mai tudásunk szerint a különböző kinurenin-származékok előállításáért felelős metabolikus útvonalak egyensúlyának felborulása fontos szereppel bírhat bizonyos betegségek, köztük egyes kardiovaszkuláris megbetegedések kórlefolyásában. Több tanulmány is alátámasztja, hogy számos kinurenin-metabolit koncentrációjának változása kimutatható koszorúér-betegségben szenvedő páciensektől nyert vér- és/vagy vizeletmintákban. Egyes közlemények szerint bizonyos kinureninek szérumszintje korrelálhat a koronáriabetegségek progressziójával. Összefoglaló tanulmányunk célja annak áttekintése, hogy a kinureninek szereppel bírhatnak-e a jövőben egyes kardiovaszkuláris betegségek rizikóbecslésében, mint biomarkerek, illetve segíthetik-e új terápiás stratégiák kidolgozását.
Az új jelszó a csökkent ejekciós frakcióval járó szívelégtelenség bázisterápiájában: ASAP!
Authors: Kovács Árpád
Published: November 2023

A csökkent bal kamrai ejekciós frakcióval (≤40%) járó szívelégtelenség (HFrEF) gyógyszeres kezelése fordulóponthoz érkezett. Az irányelv ajánlása alapján a bázisterápia jelenleg renin-angiotenzin rendszer (RAS) gátló, nátrium-glükóz-kotranszporter-2- (SGLT2-) gátló, mineralokortikoid-receptor-antagonista (MRA) és béta-blokkoló (BB) kezelés. RAS-gátlóként primeren ugyan angiotenzinkonvertáló enzimgátló (ACEi) vagy intolerancia esetén angiotenzinreceptor-blokkoló (ARB) javasolt, de az evidenciák alapján a sacubitril/valsartan (ARNi) kombináció a mindinkább preferálandó választás. Mindazonáltal, az ACEi/ARB/ARNi-t, az SGLT2-gátlót, az MRA-t és a BB-t együtt adva érhető el a legnagyobb terápiás előny. Lényeges, hogy nincs hierarchia vagy preferencia ezen 4 gyógyszercsoport között. Fontos hangsúlyoznunk a kórházi kezelés során indított és beállított bázisterápia prognosztikai jelentőségét. Ebben a beteg klinikai profilja a mérvadó, de SGLT2-gátlóval gyakorlatilag minden fenotípus esetén ideális indítani. Kulcskérdés a terápia ütemezése is, ugyanis ARNi és SGLT2-gátló kezeléssel már 2-4 hét alatt szignifikáns klinikai előny érhető el. Nem elfogadható tehát hónapokig titrálni a négyes bázisterápiát. Az új jelszó az „ASAP”, azaz akcelerált stratégia a prognózisért, ami azt jelenti, hogy a lehető leghamarabb („as soon as possible”) állítsuk be az ACEi/ARB/ARNi, SGLT2-gátló, aldoszteronantagonista (azaz MRA) és pulzuscsökkentő (azaz BB) kezelés kombinációját (grafikus absztrakt).
Molybdenum(0) tricarbonyl complex supported by an azacalixpyridine ligand: Synthesis, characterization, surface deposition and conversion to a molybdenum(VI) trioxo complex with O2
Authors: Clausen Kai Uwe , Schlimm Alexander , Bedbur Katja , Näther Christian , Strunskus Thomas , Fu Ling , Gruber Manuel , Berndt Richard , Tuczek Felix
Published: November 2023

Adsorption of metal-organic complexes on metallic surfaces to produce well-defined single site catalysts is a novel approach combining the advantages of homogeneous and heterogeneous catalysis. To avoid the “surface trans-effect” a dome-shaped molybdenum(0) tricarbonyl complex supported by an tolylazacalix[3](2,6)pyridine ligand is synthesized. This vacuum-evaporable complex both activates CO and reacts with molecular oxygen (O2) to form a Mo(VI) trioxo complex which in turn is capable of catalytically mediating oxygen transfer. The molybdenum tricarbonyl- and trioxo complexes are investigated in the solid state, in homogeneous solution and on noble metal surfaces (Cu, Au) employing a range of spectroscopic and analytical methods.
Investigation of extraneous peak reveals ethylene oxide in food supplements
Authors: Siddiqui Abdulla , Al Shareef Ahmed Jaber , Jagadeesan Premanandh
Published: November 2023

The global food supplement market is growing rapidly and so as the concerns on their quality, safety, and product efficacy. Product monitoring is challenging due to lenient regulation across the globe when compared to pharmaceutical counterparts. As part of quality and safety compliance of food supplements, products are being tested randomly in the Emirate of Abu Dhabi, UAE. This study is the part of routine monitoring of supplements during which an extraneous peak was observed and characterized. Analysis was performed using a Gas chromatography coupled to mass spectrometry and headspace extraction sampler. The extraneous peak with signal to noise ratio (S/N) of 140 was identified as ethylene oxide. Since traces were observed in active product formulation, it is worthwhile to monitor the levels in a higher number of supplements to elucidate its significance.
Unlocking the Secrets of an Ideal Solid Fast Ion Conductor
Authors: Sau Kartik , Takagi Shigeyuki , Ikeshoji Tamio , Kisu Kazuaki , Sato Ryuhei , Santos Egon Campos dos , Li Hao , Mohtadi Rana , Orimo Shin-ichi
Published: November 2023

All-solid-state battery (ASSB) is a possible alternative to the conventional Li-ion battery (LIB). ASSB, consisting of solid-fast-ion-conducting electrolytes and electrodes, can surpass LIB in terms of energy density, battery safety, specific power, and fast-charging capability. A highly conductive solid electrolyte is a prerequisite part of ASSB. Despite the last couple of decades of research dedicated to finding suitable materials, only a few have high ionic conductivity near room temperature (RT). To develop fast ion-conducting materials, both synthesis of novel high-conductivity materials near RT and a fundamental understanding of their ion transport mechanisms are essential for establishing suitable guidelines. However, it is a monumental task because of several challenges, such as enormous variations of the ionic conductivity, even within the same class of materials, indicating the strong influence of structural modifications on ion transport. In this review, a few selected material classes, namely layered oxides, polyhedral connections, and cluster anion types, are presented. Emphasis is placed on the inherent challenges in comprehending the intricate nature of these materials. Leveraging theoretical frameworks and insights from materials science, strategies to address these challenges are elucidated. Furthermore, this review covers the systematic trend from the previously reported results and presents a few new insights.
Clinical importance of evaluation of circulating miRNA expression and epicardial adipose tissue thickness as predictors of cardiovascular pathology in young patients with type 1 diabetes mellitus
Authors: Vengrzhinovskaya Oksana I. , Bondarenko Irina Z. , Shatskaya Olga A. , Tarbaeva Natalia V. , Korneluk Anastasya Y. , Kalashnikov Victor Y. , Shestakova Marina V. , Mokrysheva Natalia G.
Published: November 2023

Cardiovascular disease (CVD) in type 1 diabetes mellitus (T1DM) is preceded by asymptomatic changes in the geometry of the heart. The only symptoms of the beginning of cardiac remodeling and concomitant predictors of an unfavorable cardiovascular prognosis are: thickening of epicardial fat (EAT), secreting a number of adipokines, and cardiospecific miRNAs. To improve the effectiveness of prevention of CVD in young patients with DM1, a search was made for structural-functional and epigenetic markers.
Aim. To assess the state of the cardiovascular system according to MRI-heart with T1 mapping in T1DM without CVD. To reveal the relationship of epigenetic markers (circulating miR-126-5p, miR-21-5p) and adipokines with cardiovascular system in T1DM. Suggested personalized approach to patients with T1DM with initial manifestations of joint remodeling and/or exclusion of cardiospecific microRNA.
Materials and methods. The study included 40 patients: 30 with T1DM (age 26.2±7.4 years), 10 without T1DM (26.4±8.2). The patients underwent a general clinical examination, bioimpedancemetry, electrocardiography, MRI of the heart with T1 mapping, determination of adiponectin, resistin, visfatin, NT-proBNP, miR-126-5p, miR-21-5p.
Results. Patients with T1DM had lower levels of cardioprotective miR-126-5p (p=0.046). According to MRI of the heart in T1DM, signs of vascular remodeling were revealed – thickening of the interventricular septum (p=0.001), posterior wall (p=0.012) and relative size of the walls (p=0.048) of the left ventricle, an increase in EAT density (p=0.001). Diffuse vascular fibrosis was found in 16% of patients from the T1DM group. Also, in T1DM, the expression of visfatin is increased (p=0.036) and adiponectin is reduced (p=0.043).
Conclusion. Structural and functional changes in the cardiovascular system (including thickening of the EAT), shifts in miR-126-5p expression and adipokines profile are observed already at a young age in patients with T1DM. In T1DM, diffuse vascular fibrosis is detected in 16% of patients. The data obtained were used to identify the group increased risk of developing CVD in T1DM and served as the basis for determining the timing of the start of preventive therapy.
Simultaneous living donor pancreas-kidney transplantation in a patient with type 1 diabetes mellitus after program hemodialysis. Case report
Authors: Severina Anastasia S. , Tskaeva Alla A. , Yevloyeva Madina I. , Shamhalova Minara S. , Shestakova Marina V.
Published: November 2023

Simultaneous pancreas-kidney transplantation is an effective treatment option for end-stage renal disease with diabetes mellitus. Successful simultaneous pancreas-kidney transplantation allows achieving euglycemia, stabilizing existing microvascular complications and slowing their progression, improving the patient’s quality of life, lipid and calcium-phosphorus metabolism, reducing the risks of cardiovascular events. Therefore, in view of the patient’s severe general condition due to prolonged intoxication, hyperglycemia and other complications of chronic kidney disease, the earliest possible surgical treatment with minimization of the patient's stay on dialysis therapy is crucial to improve the outcome of transplantation.
Progressive radiation-induced rectal injury: is there an opportunity to get out of a vicious circle? A clinical case
Authors: Skvortsova Tatyana E. , Oganezova Inna A. , Medvedeva Olga I.
Published: November 2023

Radiation therapy is one of the main treatment option for prostate cancer used either independently or as a component of combined and complex treatment of the disease. Modern achievements make it possible to deliver doses of radiation that match the exact dimensions of the tumor for greater efficacy, with minimal exposure of the surrounding tissues, however, does not eliminate them. In most patients, clinical manifestations of chronic radiation proctitis occur during the first 2 years after radiation therapy. The article summarizes the current knowledge about pathophysiology, clinical manifestations, diagnostics and treatment options for this condition. In this paper, we present a case of complicated of chronic radiation proctitis.
Sex on the brain: Contradictions in the neuroscience of sex
Authors: Grimshaw Gina
Published: November 2023

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Changing the culture: A first-hand example
Authors: Simpson Cather
Published: November 2023

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What young graduates earn when they leave study
Authors: Park Zaneta , Mahoney Paul , Smart Warren , Smyth Roger
Published: November 2023

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What young graduates do when they leave study – New data on the destinations of young graduates
Authors: Park Zaneta
Published: November 2023

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Rutherford, the Life and Work, on DVD
Authors: Clare John
Published: November 2023

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The Constitutions of the Kingdom of Thailand: Elite-Constructed Constitutions (1932-1974)
Authors:   , Nachan Natdanai
Published: November 2023

Thai constitutional history is characterised by cyclic coups and multiple constitutional promulgations. In my thesis, I argue that the dominant conception of constitution-making, which posits that constitutions are constructed through the exercise of “the people’s” constituent power and must be adopted through democratic processes, is insufficient in explaining the history of Thai constitutional development. The thesis argues that Thai constitutional history needs to be explored through what I will call ‘the elite-constructed constitution approach’.

This thesis elaborates on the elite-constructed constitution approach. It is supported by political science literature concerning political elites’ role in politics. Legal literature on the role of political elites in the constitution-making process is also used to structure an understanding of the constitution as a contract resulting from the negotiations of political elites in the constitution-making process. The contract’s primary purpose is to serve political elites’ interests. In order to assess the efficacy of the elite-constructed constitution approach to explain Thai constitutional history, I applied this framework to examine the constitution-making processes and resulting constitutions from 1932 to 1974. This period is significant as it marks the beginning of written constitutionalism in Thailand (1932), and the first instance in which ordinary citizens were able to genuinely influence a constitution-making process in 1974. The study’s findings suggest that most constitutions created during this period were elite-constructed in nature, meaning they were designed to serve political elites’ benefit and were dependent upon elites’ willingness to maintain them. Only the Constitution of 1974 that emerged from the process that did not fully conform to the specific criteria of an elite-constructed constitution. This constitution displayed characteristics that were a blend of the dominant conception of constitution-making and the elite-constructed constitution approach.

The study suggests that the elite-constructed constitution approach explains Thailand’s constitutional evolution from 1932 to 1974. However, further research is necessary to determine its applicability to the country’s entire constitutional development, including post-1974 constitutions. Additionally, it is essential to investigate whether this approach can elucidate the constitutional development of other nations beyond Thailand.
The Teutonic Order and monasteries in Gdańsk Pomerania in the first half of the 14th century
Authors: Kubicki Rafał
Published: November 2023

Przedmiotem opracowania jest próba charakterystyki polityki prowadzonej przez zakon krzyżacki (niemiecki) wobec klasztorów na Pomorzu Gdańskim w pierwszej połowie XIV w. W dotychczasowych ocenach tradycyjnie wskazywano na konsekwentnie stosowane ograniczenia odnośnie do fundacji klasztorów mniszych w Prusach i dążenie zakonu niemieckiego do poddania ścisłej kontroli wszystkich zgromadzeń posiadających swoje siedziby na Pomorzu Gdańskim. W artykule wskazano przede wszystkim na dwa czynniki mające wpływ na relacje zakonu niemieckiego z klasztorami na Pomorzu Gdańskim, to jest na proces implantacji klasztorów i terytorializacji urzędów zakonu niemieckiego na Pomorzu Gdańskim. Z przeprowadzonych analiz wynika, że relacje zakonu niemieckiego z klasztorami na Pomorzu Gdańskim były nie tyle następstwem konsekwentnie realizowanej przez niego polityki, ale raczej wypadkową wielu czynników, wynikających z sytuacji panującej w danym zgromadzeniu zakonnym (cystersi) i odnośnie do konkretnego klasztoru (przy kład dominikanów w Gdańsku). Przy czym zakon niemiecki występował zazwyczaj jako władca terytorialny, potwierdzający transakcje kupna–sprzedaży względnie nadania lub zamiany dóbr oraz jako arbiter w sporach z innymi instytucjami (z władzami miejskimi). Funkcję taką pełnili miejscowi komturzy lub sam wielki mistrz zakonu. Udział tego ostatniego był zazwyczaj związany z potrzebą ogólnej regulacji, jak w przypadku generalnej konfirmacji dla dóbr klasztoru w Oli wie i Żarnowcu dokonanej przez wielkiego mistrza Ludolfa Königa. Ogólnie, wzajemne relacje zakonu z klasztorami były poprawne, jeśli nie wręcz dobre. Trzeba też podkreślić, że stanowisko zakonu niemieckiego wobec klasztorów na Pomorzu Gdańskim było elementem szerszej polityki kościelnej prowadzonej na tym terenie także wobec biskupa włocławskiego i arcybiskupa gnieźnieńskiego.
Kilka uwag na temat obrazu „idealnego władcy” Teodoryka Wielkiego w świetle „Variae” Kasjodora Senatora (część pierwsza)
Authors: Wojcieszak Maciej
Published: November 2023

In this article, the author analyzes letters from the royal chancellery of Theodoric the Great in terms of creating an image of an “ideal” Christian ruler via the example of Theodoric. The article opens with an introduction in which the issues analyzed are outlined. Then the six main features are set out of the “ideal” Christian ruler emerging from the image created in the letters from the royal chancellery of Theodoric. Because of the abundance of source material, it has been necessary to divide the article into two parts. In the first part, we dis cuss the three most common features in the sources: fair and law-abiding, caring for his people, caring for the development of the state. The first part ends with a short summary. In the second part, we will discuss the next three features, which include: dealing with military affairs, skillfully conducting “foreign policy”, being distinguished by Christian virtues, and caring for the Church. In the second part, we will present a summary that contains conclusions about the image of an “ideal” Christian ruler presented via the example of Theodoric. Letters from the chancellery, presided over by Cassiodorus Senator, are a valuable source for early-medieval Italy under Ostrogoth rule. We can see in them the changes that took place in the society of that time after the collapse of the western structures of the Roman Empire.
Документ і влада на Галицькій Русі пізнього середньовіччя (У зв’язку з монографією Sven Jaros, Integrationen im Grenzraum. Akteure und Felder multikonfessioneller Herrschaftsaushandlung in Kronruthenien (1340–1434), Berlin–Boston 2021
Authors: Зазуляк Юрій
Published: November 2023

The article provides an overview of the recent book written by the German historian Sven Jaros which examines the history of the political process, local elites, and the documentary culture in Halych Rus’ (Red Ruthenia) during the period of the 1340s – 1430s. The book offers a new interpretation of the power relations and the formation of the local elites in the region with a focus on the detailed analysis of the charters issued by the rulers from the Piast, Anjou, and Jagiellon dynasties, as well as by their governors for the local noblemen, townsmen, and commoners. In his analysis Jaros discusses the composition of the groups of the recipients of charters according to their ethnic, social, and geographic origin. The analysis continues with an examination of the mobility of the rulers, governors, and recipients. It seeks to trace the connections between the geographies of the issue of a charter, the property granted, and the residence of the recipients. The book contains short excursions on the beginnings of the Latin Church and the state of the Orthodox Churches in Crown Rus’ under the rule of Casimir III, the Great, as well as on the practices of cura animarum in the region. Jaros concludes that the continuity and changes in the forms of local political communication and the political order, as reflected in the rulers’ charters for Crown Rus’, determined the political and institutional space for the formation of the local nobility as a supra-ethnic and supra-confessional community. The second part of the book consists of a register (repertorium) of all known charters and their deperdita issued for the region’s recipients by the rulers and their governors during the given period. The register is accompanied by observations on the main characteristics of the available corpus of diplomas and charters for the history of Galicia, which highlights the institutional means of their preservation, the correlation between the surviving originals and copies, the mentions of lost documents, etc. The review also offers alternative explanations of some problems raised in the book, such as how some local knightly clans were formed, or the nature of military service and property rights in the lands of Halych Rus’ and its relations to the written documents issued to confirm such rights.
KEPUASAN BELAJAR SISWA TERHADAP PEMBELAJARAN SENI BUDAYA DI MTsN 3 KABUPATEN 50 KOTA PADA MASA PANDEMI COVID-19
Authors: Mulyadi Hamda , Muchtar Amrizal , Saputra Nefri Anra
Published: November 2023

Penelitian yang berjudul “Kepuasan Belajar Siswa terhadap Pembelajaran Seni Budaya di MTsN 3 Kabupaten 50 Kota Selama Masa Pandemi Covid-19” ini bertujuan untuk menganalisis kepuasan belajar siswa dan mengklasifikasikan faktor-faktor yang mempengaruhi kepuasan belajar siswa terhadap pembelajaran seni budaya pada masa pandemi covid- 19 . Penelitian ini dilakukan di MTsN 3 Kabupaten 50 Kota yang beralamat di Jalan Tan Malaka km.12 Jorong Guguak VIII Koto, Kecamatan Guguk. Metode dan teknik pengumpulan data yang digunakan adalah metode kualitatif melalui wawancara. Teknik analisis yang digunakan berupa hasil studi kepustakaan, observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa terjadi perubahan dalam proses pembelajaran, siswa yang sebelumnya belajar di sekolah,sekarang siswa belajar di rumah mengakibatkan perubahan sikap dan perilaku siswa. Perubahan sikap dan perilaku siswa tersebut disebabkan tidak terpenuhinya kepuasan siswa dalam belajar seni budaya selama masa pandemi covid-19. Faktor penyebab tidak terpenuhinya kepuasan belajar siswa dalam pembelajaran seni budaya pada masa pandemi covid-19 adalah karena terpenuhinya kebutuhan belajar siswa dan tidak terpenuhinya harapan belajar siswa.                                    Kata Kunci : Belajar, Pandemi Covid-19, Pembelajaran Seni Budaya ABSTRAKPenelitian yang berjudul “Kepuasan Belajar Siswa terhadap Pembelajaran Seni Budaya di MTsN 3 Kabupaten 50 Kota Selama Masa Pandemi Covid-19” ini bertujuan untuk menganalisis kepuasan belajar siswa dan mengklasifikasikan faktor-faktor yang mempengaruhi kepuasan belajar siswa terhadap pembelajaran seni budaya pada masa pandemi covid- 19 . Penelitian ini dilakukan di MTsN 3 Kabupaten 50 Kota yang beralamat di Jalan Tan Malaka km.12 Jorong Guguak VIII Koto, Kecamatan Guguk. Metode dan teknik pengumpulan data yang digunakan adalah metode kualitatif melalui wawancara. Teknik analisis yang digunakan berupa hasil studi kepustakaan, observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa terjadi perubahan dalam proses pembelajaran, siswa yang sebelumnya belajar di sekolah,sekarang siswa belajar di rumah mengakibatkan perubahan sikap dan perilaku siswa. Perubahan sikap dan perilaku siswa tersebut disebabkan tidak terpenuhinya kepuasan siswa dalam belajar seni budaya selama masa pandemi covid-19. Faktor penyebab tidak terpenuhinya kepuasan belajar siswa dalam pembelajaran seni budaya pada masa pandemi covid-19 adalah karena terpenuhinya kebutuhan belajar siswa dan tidak terpenuhinya harapan belajar siswa. Kata kunci : tujuan belajar, pandemi covid-19, pembelajaran, seni budaya
Природа химической связи Pt-Os в наносплавах
Authors: Асанов И.П. , Зверева В.В. , Федоренко А.Д. , Асанова Т.И.
Published: November 2023

Методами рентгеновской фотоэлектронной спектроскопии и рентгеновской спектроскопии поглощения исследована электронная структура биметаллических наносплавов состава Os0.5Pt0.5. На основании экспериментальных данных определены электронная заселенность на атомах в сплавах. Показано, что при образовании сплава происходит перенос электронов с атомов Os на Pt, а знак и величина химического сдвига в значительной степени определяется потенциалом Маделунга. Анализ формы спектров РФЭС внутренних линий и валентной полосы показывает увеличение локальной плотности состояний на атомах Os вблизи уровня Ферми. На основании параметров валентной d-зоны обсуждаются перспективы использования наносплавов в каталитических реакциях.
A Novel Broadband Filtenna with using SRR and DGS for Wireless Communication Applications
Authors: ARICAN Galip Orkun , KARAHAN Mert
Published: November 2023

This paper presents a novel broadband filtenna design for 5G applications. The filtenna structure comprise of a bow tie slot loaded path antenna with a four-pole lowpass filter structure on the feed-line. In addition, the defected ground structure method was applied to miniaturize the size and widen the operating frequency bandwidth. The proposed filtenna was designed and optimized with utilizing Keysight’s PathWave EM Design (EMPro) software. In addition, the filtenna design was analysed with utilizing four different substrates, which are Rogers RT5880, RO3003, RO4003 and RT6006, and the electromagnetic simulation results were presented. Moreover, the design was manufactured with utilizing Rogers RT5880 and the design was validated with the measurements. The developed filtenna operates at a centre frequency of 3.9 GHz and the operating frequency bandwidth of 2.86 to 4.89 GHz which yields a fractional bandwidth of 52%. Furthermore, the filtenna has a reflection coefficient better than -10 dB and the measured maximum antenna gain was 3.26 dBi. The filtenna has a compact size of 0.463λ_0×0.506λ_0 where λ_0 is the wavelength at the center frequency. The proposed filtenna can be utilized for 5G applications with its compact-size, low-cost and high-performance characteristics.
Aşındırıcı Su Jeti Sisteminde Farklı Parametrelerle Kesilmiş Lif Levhanın Pürüzlülük Özelliklerinin İncelenmesi
Authors: PELİT Hüseyin , YAMAN Özkan
Published: November 2023

Bu çalışmada, aşındırıcı su jeti (ASJ) sisteminde farklı işleme parametreleri ile kesilen orta yoğunluklu lif levha (MDF) örneklerin kenar pürüzlülük özelliklerinin belirlenmesi amaçlanmıştır. 18, 36 ve 54 mm kalınlıklarında hazırlanmış olan lif levhalar, ASJ sistemi ile 50, 100 ve 200 mm/dk ilerleme hızı; 200, 300 ve 450 gr/dk aşındırıcı kütle akış oranı; 300 ve 380 MPa kesici sıvı basıncı uygulanarak kesilmiştir. Örneklerde kesim yüzeyi özellikleri Ra, Rq ve Rz pürüzlülük değerleri analiz edilerek belirlenmiştir. Çalışma sonuçlarına göre, lif levha kalınlığı ve ASJ ilerleme hızı artışına bağlı olarak pürüzlülük özellikleri de artmıştır. Diğer taraftan, aşındırıcı miktarı ve kesici sıvı basıncındaki artış ile pürüzlülük değerleri genel olarak azalma eğilimi göstermiştir. Ancak, örneklerin pürüzlülük özelliklerinde levha kalınlığı ve ASJ ilerleme hızı parametreleri birinci derecede öneme sahipken, aşındırıcı akış oranı ve kesici sıvı basıncı parametrelerinin daha az bir öneme sahip olduğu belirlenmiştir.
Successful treatment of Caparinia tripilis infestation with ivermectin in an African pygmy hedgehog
Authors: Budiono Novericko Ginger , Wen Nicole Ting Qian , Rajendran Punithe Raj A/L
Published: November 2023

Acariasis is a prevalent disease in Atelerix albiventris or African pygmy hedgehogs, with Caparinia tripilis being the main aetiologic agent. This case report describes a single instance of C. tripilis mange in a 16-month-old African pygmy hedgehog detected through clinical and microscopic skin scraping investigations. The owner brought the hedgehog to the IPB University Veterinary Teaching Hospital, complaining about inappetence, intense pruritus, diarrhoea, and crusts in the patient. Faecal native and flotation showed no helminthic or protozoan parasites. The treatment comprised subcutaneous ivermectin application at a dose of 0.4 mg/kg body weight. The control was made 14 and 28 days after the first hospital visit, with ivermectin applications at the same dose (three doses in total and two weeks apart from each dose). Microscopic examination of the skin scrapings was performed on days 14 and 28, and C. tripilis was not observed in these examinations. Complete clinical improvement was observed during the two control examinations. This is the first report to describe the use of a three-dose (two weeks apart) of ivermectin to treat capariniasis in an African pygmy hedgehog in Indonesia.
PELATIHAN TANGGUH BENCANA DESA WISATA KUTA, LOMBOK TENGAH: MITIGASI BENCANA GEMPA UNTUK MASYARAKAT
Authors: S. Agustawijaya Didi , Murtiadi Suryawan , Mahendra Made , Muhajirah Muhajirah , Suteja I Wayan , Sulistiyowati Tri
Published: November 2023

Desa Kuta merupakan kawasan wisata di Kecamatan Pujut, Lombok Tengah, bagian dari KEK Mandalika. Kawasan ini terletak di bagian selatan Pulau Lombok yang mempunyai tinggkat kerentanan tinggi terhadap bahaya gempa. Masyarakt di Desa Kuta belum memahami risiko kegempaan yang mereka hadapi. Walaupun di desa tersebut telah terbentuk Taruna Tanggap bencna (TAGANA) dan Desa Kuta telah mendapatkan sertifikat UNESCO untuk desa tangguh bencana. Untuk itu perlu dilakukan sosialisasi tentang risiko bencana gempa, begitu juga peningkatan pemahaman tentang pengelolaan risiko gempa terhadap pelaku TAGANA. Sosiaisasi dilaksanakan dengan melibatkan mahasiswa KKN tematik Desa tangguh bencana; dan pelatihan terhadap pelaku TAGANA. Hasil yang terlihat dari kegiatan sosialisasi ini adalah antusia para pelaku TAGANA terutama dalam menambah wawasan tentang risiko bencana gempa untuk Desa Kuta. Hasil ini diharapkan dapat diterapkan oleh pelaku TAGANA dalam mengurangi risiko bencana baik dalam mitigasi maupun penangan bencana.
ANALISIS METODE PENYELESAIAN SENGKETA KEWARISAN ISLAM DI INDONESIA
Authors: Fatahullah Fatahullah , Salat Musakir , Haerun Haeratun , Jamaludin Jamaludin
Published: November 2023

Fenomena perubahan sikap/perilaku masyarakat dalam hal pembagian warisan yang tidak mengindahkan kultul atau budaya dan adat istiadat dalam masyarakat dapat merubah tatanan sosial yang selama ini diyakini oleh masyarakat. Salah satu sengketa yang sering muncul dimasyarakat adalah sengketa terhadap harta warisan. Penyelesaian sengketa tersebut dapat dilakukan melalui litigasi dan melalui non litigasi. Peran kepala desa menjadi sangat penting dalam upaya pertama untuk menghindari konflik terhadap harta warisan. Adapun tujuan dari pelaksanaan pengabdian ini adalah sebagai wujud pelaksanaan tri darma dalam bentuk memberikan pemahaman dalam penyelesaian sengketa kewarisan. Sedangkan manfaatkan atas pelaksanaan pengabdian ini adalah Masyarakat akan mengetahui prosedur, manfaat dan akibat hukum terhadap setiap pilihan dalam penyelesaian sengketa warisan. Metode kegiatannya adalah ceramah interaktif dan diskusi peserta. Dalam pelaksanaan pengabdian diketahui bahwa masih banyak Masyarakat yang masih bingung dengan system hukum kewarisan perdata, adat dan agama. Sehingga mencampuradukan ketiga system tersebut dan yang terpenting para ahli waris mendapatkan haknya walaupun dengan nilai yang berbeda-beda. Masyarakat memahami kewarisan adat berdasarkan pada kebiasaan turun-temurun. Sedangkan kewarisan agama khususnya Islam dipahami dari tokoh agama atau Tuan Guru yang ada di desa. Secara umum Masyarakat memahami bagian-bagian dalam hukum kewarisan agama. Akan tetapi dalam pelaksanaannya mereka mencampurkannya dengan hukum waris adat, misalnya dengan system hibah wasiat. Kalaupun ada masalah warisan, itu terjadi setelah pewaris meninggal dunia dan diselesaikan dengan system kekeluargaan oleh pemangku Masyarakat baik ditingkat dusun maupun oleh kepala desa. Tetapi ada juga yang tidak puas dan menyelesaikannya melalui Lembaga peradilan, sekaligus bertujuan untuk lebih memberikan kepastian hukumnya.
A FIBRILAÇÃO ATRIAL ASSOCIADA A INFECÇÃO DO COVID-19: INCIDÊNCIA, PREVALÊNCIA, FISIOPATOLOGIA E PROGNÓSTICO - UMA REVISÃO BIBLIOGRÁFICA
Authors: Castanho Maria Fernanda Fontes de Paula , Beatto Gabriell Henrique Riedi , Filha Regina Keiko Sato Mizuno , Farias Lucas da Cruz , Gonçalves Iasmim Luisa Batista , Castanho Ronaldo Fontes De Paula , Cury Anny Sibelly Dias , Silva Dyeslen Keise Alves Da , Neves Filho Edwilson Francisco , Gonçalves Rafael Dos Santos , Pereira Junior Renato Aparecido , Brandão Miriam De Andrade , Paciencia Gabriel de Paula
Published: November 2023

Introdução: O coronavírus (SARS-CoV-2), causador da doença sistêmica COVID-19 provoca sintomas respiratórias de aspecto clínico amplo, porem, doenças cardiovasculares e complicações frequentemente aco
ENDOMETRIOSE E INFERTILIDADE: ESTRATÉGIAS DE APOIO À FERTILIDADE
Authors: Corezzolla Aline Cristina , Araújo Gabriele Teixeira , Souza Gustavo Cordeiro Candote de , Lobato Werllison Mateus Silva , Rios Antonia Dyeylly Ramos Torres , Tôrres Raul Ricardo Rios , Dettmer Jacqueline Alves Borba de Oliveira , Costa Kelvia Borges Dos Santos , Rosa Lourivania Gonçalves , Paiva Jocilene da Silva
Published: November 2023

A endometriose é uma condição ginecológica crônica caracterizada pela presença de tecido
endometrial fora do útero, afeta aproximadamente 10% das mulheres em idade reprodutiva. Além
dos sintomas dolorosos e incapacitantes que a endometriose pode causar, muitas mulheres também
enfrentam desafios relacionados à infertilidade. A relação entre endometriose e infertilidade tem
sido amplamente estudada, e várias estratégias de apoio à fertilidade têm sido desenvolvidas para
auxiliar as mulheres afetadas (GIUDICE, 2010).
Neste contexto, uma das principais preocupações é entender como a doença afeta a reserva
ovariana e a qualidade dos óvulos. Estudos demonstraram que mulheres com endometriose podem
apresentar uma diminuição da reserva ovariana e uma maior proporção de óvulos de baixa
qualidade (JOHNSON; HUMMELSHOJ, 2013). Esses achados ressaltam a importância de
estratégias de apoio à fertilidade que visem melhorar a qualidade e a quantidade de óvulos
disponíveis para a fertilização.
Herança de Ilusões
Authors: Vieira Aparecida M
Published: November 2023

"Herança de Ilusões" é um eletrizante romance de suspense que mergulha nas profundezas da traição e do engano na era digital. A história gira em torno de Júlia, uma advogada astuta e determinada, que se encontra em meio a um dos casos mais desafiadores de sua carreira. O livro traz uma trama envolvente, onde crimes e manipulações são orquestrados através do WhatsApp, revelando o lado sombrio da tecnologia que permeia nossa vida cotidiana.
No cerne deste mistério está o intrigante caso de Francisco e Gisely, envoltos em uma teia de mentiras tecida habilmente por Amanda Rodrigues, uma personagem aparentemente confiável. A cada mensagem trocada no WhatsApp, um novo véu de mistério é revelado, mostrando como a tecnologia pode ser usada para manipular e enganar. Júlia, enfrentando reviravoltas dignas de um thriller, luta não apenas para desvendar a verdade, mas também para manter intacta sua ética profissional.
A narrativa, repleta de suspense, convida o leitor a mergulhar nesse universo onde nada é o que parece. As mensagens trocadas entre os personagens se entrelaçam em uma dança perigosa de segredos e ilusões, conduzindo a um clímax surpreendente. "Herança de Ilusões" é mais do que um livro; é um espelho da nossa realidade, onde a verdade e a ficção se confundem nas telas dos nossos smartphones.
Prepare-se para ser cativado por esta história envolvente, onde cada página virada aumenta o suspense, deixando o leitor ávido por desvendar os segredos ocultos nas mensagens de WhatsApp e nas sombras da natureza humana. "Herança de Ilusões" não é apenas uma leitura; é uma experiência que te desafia a questionar até onde você conhece as pessoas ao seu redor e a própria tecnologia que utiliza.
Execução em litígios estruturais
Authors: Gomes Brenda Karla Evangelista
Published: November 2023

A execução estrutural é compreendida como a reordenação de uma instituição pela jurisdição, apresentando desafios na implementação de medidas estruturantes. A flexibilização procedimental e a participação das partes são sugeridas como estratégias para superar esses desafios. O artigo aborda as definições de processo estrutural, problema ou litígio estrutural, fazendo análise das suas características em função da necessidade de efetividade das decisões em litígios estruturais. Nesse sentido, busca contribuir para a compreensão dos processos estruturais, desde sua origem até a execução, explorando suas características e enfatizando a necessidade de soluções negociadas e participação democrática para uma execução efetiva.
O falseamento de ideias como defesa do próprio pensamento e da ciência
Authors: Segundo Hugo de Brito Machado , Machado Raquel Cavalcanti Ramos
Published: November 2023

Durante o século XX, a Ciência enfrentou uma série de críticas e ataques, muitos deles originados por pesquisadores dedicados que levantaram questionamentos sobre a metodologia empregada e suas limitações. No cenário jurídico brasileiro, a fragilidade das pesquisas é ainda mais pronunciada em razão do aumento do número de cursos de graduação, mestrado e doutorado, nos quais a elaboração de trabalhos científicos é requisito para a obtenção de títulos. Diante da importância histórica da pesquisa científica e de seu notável potencial transformador, apresenta-se fundamental sua condução com base em uma metodologia rigorosa. Estabelece-se, assim, uma comparação entre a abordagem de pesquisa nas Ciências Naturais e nas Ciências Sociais Aplicadas, destacando a essencialidade de questionar e superar adversidades. Destaca-se também a relevância de compartilhar os resultados da pesquisa de maneira clara e objetiva, demonstrando respeito pelo compromisso temporal e intelectual do pesquisador. A dialética destaca-se como uma ferramenta essencial, demandando que o pesquisador considere e enfrente os argumentos contrários a fim de fortalecer a sua própria hipótese. Esta abordagem é especialmente crucial no âmbito jurídico, no qual questões de controvérsia precisam ser tratadas com sinceridade e abertura. É relevante sublinhar que se patrocina a ideia de que a promoção do pensamento científico exige diálogo e tolerância, sendo imperativo reconhecer que a diversidade de perspectivas contribui significativamente para o avanço tanto da Ciência quanto da sociedade em si. Em conclusão, o trabalho enfatiza a importância inegável de conduzir pesquisas de maneira responsável, comprometida com a busca pela verdade científica no contexto do campo jurídico.
Demandas estruturais do direito à saúde no contexto da pandemia da Covid-19 e o Estado de Coisas Inconstitucional
Authors: Lucena Victor Felipe Fernandes de
Published: November 2023

Investigam-se as demandas estruturais do direito fundamental à saúde no contexto da pandemia da Covid-19, considerando o direito sanitário como mínimo existencial e integrante da dignidade da pessoa humana em face da teoria da reserva do possível, alegada não raras vezes pelo Estado em sua tese defensiva, constituindo-se em entrave para a sua efetivação. Nessa perspectiva, a busca pela realização desse direito tem ensejado inúmeras ações judiciais a fim de compelir o Poder Público à sua prestação, inclusive com manifestações do STF sobre o tema. No entanto, a solução para o problema estrutural da seara sanitária não reside apenas na ação do Poder Judiciário compelindo os demais órgãos a garantir o acesso dos cidadãos aos seus direitos, mas em uma macrossolução em um processo estrutural, com a possível declaração do estado de coisas inconstitucional favorecendo a realização de um diálogo institucional, uma ação conjunta e integrada de todos os poderes da República no cumprimento de um plano estratégico comum sob permanente jurisdição, objetivando solucionar, por vez, o caos estrutural em que se encontra o serviço público de saúde no Brasil. Para a formulação das conclusões apresentadas, utiliza-se como metodologia a pesquisa bibliográfica doutrinária e jurisprudencial e o método hipotético-dedutivo e exploratório.
Perfis da decisão judicial ante a automação do Poder Judiciário
Authors: Praciano Lanna Beatriz Sampaio
Published: November 2023

Objetiva-se, por meio da presente pesquisa, estudar os critérios que fazem parte do processo decisório no âmbito do Poder Judiciário, levando em consideração, para tanto, a contraposição entre subjetividade e racionalidade. Ademais, apresentadas as perspectivas da decisão judicial, pretende-se analisar os impactos que a automatização da seara jurídica pode ocasionar para a sociedade, estudando como a ciência do direito se comporta diante dessa nova realidade. O estudo aborda, portanto, a partir do levantamento bibliográfico e de pesquisas qualitativas e documentais, com fins exploratórios e descritivos, uma investigação em torno da relação entre a decisão judicial, os seus respectivos critérios e a automatização do Poder Judiciário. A partir do desenvolvimento desta pesquisa será possível compreender quais os impactos gerados pela utilização, cada vez mais frequente de métodos tecnológicos no âmbito jurídico, bem como será possível tecer considerações em torno do modo como o ordenamento jurídico brasileiro apresenta soluções para a problemática elencada e as perspectivas para o futuro.
Aspectos dos resíduos sólidos ante o direito ao meio ambiente ecologicamente equilibrado
Authors: Gomes Brenda Karla Evangelista
Published: November 2023

A temática dos resíduos sólidos é um tema central no que diz respeito à tutela do meio ambiente. A geração desenfreada de resíduos está atrelada a múltiplos fatores e exigem da humanidade uma resposta urgente. Trata-se de um problema complexo, multidimensional e com as mais diversas consequências para a vida do homem, bem como para o equilíbrio das formas de vida existentes no planeta. O artigo analisa os aspectos dos resíduos sólidos em face do direito ao meio ambiente ecologicamente equilibrado, evidenciando a necessidade de caminhos para sua efetivação que envolva a participação dos diversos atores envolvidos na geração e gestão de resíduos. Como metodologia, utiliza-se de pesquisa do tipo bibliográfica, por meio da análise de livros, artigos jurídicos, documentos internacionais, da legislação e da jurisprudência. A pesquisa é pura e de natureza qualitativa, com finalidade descritiva e exploratória.
Estrategia de gestión educativa para el fortalecimiento del desarrollo socioafectivo de los estudiantes a través de un AVA en el Centro Educativo Retoñitos de Aguachica, Cesar
Authors:   , Villanueva Gascón Aghanisandris
Published: November 2023

El desarrollo socioafectivo es un proceso evolutivo que se forma desde la niñez y permite que el individuo a medida que crezca se adapte social, moral, afectivo y sexualmente en el contexto próximo a él. La presente investigación tiene como finalidad fortalecer la gestión educativa del Centro Educativo Retoñitos en la ciudad de Aguachica, Cesar, contribuyendo al desarrollo socioafectivo de los estudiantes por medio de la creación de un AVA. La metodología responde a un enfoque cualitativo bajo la modalidad de investigación proyectiva. Para tal finalidad se realizaron dos entrevistas semiestructuradas, una a las docentes y otra a los padres de familia de la institución con el objetivo de diagnosticar y caracterizar las estrategias utilizadas por estos durante las clases virtuales por la pandemia de Covid-19. Los resultados indican que dos de las dimensiones socioafectivas: la dimensión social y afectiva no tuvieron un desarrollo óptimo durante el tiempo de clases virtuales; esto debido a la falta de contacto físico por parte de los estudiantes con sus maestras y compañeros, además del tiempo de los encuentros que era muy cortó. Para el proceso de creación del AVA se tuvieron en cuenta dos factores: la conexión a una red inalámbrica que permitiera la navegación por internet y los elementos necesarios (computador y celular) para el acceso al AVA. Como recomendaciones se propone la implementación de las TIC y la formación en otras áreas de estudio. De igual forma, se deja abierta la posibilidad de incorporar en el currículo académico una asignatura que incluya aspectos relacionados con educación socioafectiva y emocional.
La comunicación bilingüe para la comprensión de contenidos de aprendizaje en estudiantes de CECIBs Shuar
Authors: Kajekai Juwa Tuntuam Klever
Published: November 2023

El estudio realizado se centra en la comunicación bilingüe para la comprensión de contenidos de aprendizaje en estudiantes de CECIBs Shuar. Se exploran conceptos sobre la lengua Shuar, su empleo en diversos contextos y se presenta el alfabeto. La investigación evalúa los beneficios educativos del Shuar Chicham en estudiantes de centros educativos bilingües en Ecuador. Se destaca la importancia del apoyo de docentes, estudiantes y padres en la preservación cultural. El trabajo revela desafíos, como la insuficiente preparación bilingüe de docentes y la influencia de factores externos en la pérdida de la lengua materna.
Problematika Penerapan Accrual Accounting Pada Lembaga Keuangan Syariah
Authors: Rosmanidar Elyanti , Prayogo Youdhi
Published: November 2023

Today, there is much debate about the basic assumptions that should be used in the financial statements of Islamic entities, namely the accrual basis and cash basis. This study will reveal that the accrual basis which is widely applied in the preparation of financial statements turns out to have many gaps to manipulate data, so that it will cause earnings management to arise. The unpopular cash basis applied in the preparation of financial reports is more able to reveal real conditions, income and expenses. This study also discusses the reasons for using the accrual basis in the framework for preparing and presenting Islamic financial statements based on PSAK 101 whereby Islamic entities must prepare financial statements on an accrual basis. This research will also show the many problems that arise in the application of accrual accounting in Islamic financial institutions today.
NUMERAL TO NUMERAL OF BALMIKI AND KUPIA: A MORPHOLOGICAL COMPARISON
Authors: Dash Biswanandan , Pattanayak Subrat Kalyan
Published: November 2023

Numeral systems are the major counting methods found across languages. They are characterised by unique morphosyntactic structures to show numericity. The efficiency of communicating numbers is related to the morphological construction of numerals. These are also valuable sources for genetic classification. Besides, they play a vital role in establishing the antiquity of a cognate language. Peculiarly, the numeral systems of languages are the most vulnerable to elimination due to major or dominant languages. The quest in this article is to analyse the numeral morphology of Balmiki, a lesser-known language spoken in Odisha, and compare it with that of Kupia, a language spoken in Andhra Pradesh by the B/Valmiki community, to determine if their numeral structures are concealed or influenced by their encroaching languages. This study further contests a louder outbreak created during 2016-18 to ‘discover the Walmiki language’ by analysing a few unreliable numeral examples. In a series, this is the second study that compares and propounds conclusively to the fact that how these duo languages shed light on shared characteristics of numerals inherited or descended in other Indo-Aryan traditions from an etymological ancestor.