bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of innovativeness on different levels of technology adoption
Authors: van Rijnsoever Frank J. , Donders A. Rogier T.
Published: February 2009

In this article, we look at the personality characteristic “global innovativeness” as a predictor for the adoption of consumer electronics; the latter being termed “actualized innovativeness.” Global innovativeness is tested as a predictor for three levels of actualized innovativeness: at the domain‐specific, cluster‐specific, and product‐specific levels. Our theoretical propositions are tested using two different surveys, one consisting of adolescent bachelor students (n= 138) and the second consisting of a heterogeneous broad sample (n= 450). The results of these studies show that the higher the level of abstraction of actualized innovativeness, the stronger the effects of global innovativeness. The implications of these findings are discussed.
Study of Diffusion of Organic Dyes in a Triblock Copolymer Micelle and Gel by Fluorescence Correlation Spectroscopy
Authors: Ghosh Subhadip , Mandal Ujjwal , Adhikari Aniruddha , Bhattacharyya Kankan
Published: February 2009

Dye‐ing to get out: Fluorescence correlation spectroscopy was used to show that diffusion coefficients depend on the location of the dye molecules in a single medium. In a micelle, hydrophobic dyes remain within the micelle, whereas a hydrophilic probe occasionally diffuses out of the micelle into bulk water. In a gel, diffusion of the micelle is completely arrested and the autocorrelation arises from diffusion of the dye.

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Fluorescence correlation spectroscopy (FCS) has been used to study translational diffusion of three fluorescent dyes in a micelle and a gel. It was demonstrated that a highly hydrophobic dye, DCM, remains confined to a particular micelle during the passage of the micellar aggregation through the confocal volume. As a result, DCM exhibits slow diffusion of the large micellar aggregate with a diffusion coefficient (Dt) approximately 25 times slower compared with that of water. In contrast, a hydrophilic probe (C343 or C480) occasionally diffuses out of the micelle into bulk water and displays a large Dt (twofold smaller in F127 and approximately six times smaller in the P123 micelle compared with that in bulk water). In a gel, diffusion of the individual micelles is completely arrested and hence, the autocorrelation in FCS arises solely from the diffusion of the dye in the gel. In this case, all the three dyes exhibit extremely slow diffusion (300, 45, and 20 times slower than that in water for DCM, C480, and C343 in F127 gel, respectively). In a P123 and F127 gel, diffusion of DCM is respectively, seven and 29 times slower compared with that of the ionic probe C343. The relatively small value of red‐edge excitation shift (REES) of the emission maximum, suggests that DCM is confined within the core of the triblock copolymer micelles and gels. The hydrophilic probes (C343 or C480) exhibit fast diffusion in the micelles and gels. However, their REES is very different. The large REES of C480 suggests that it is distributed over a large region of the micelle, whereas the low REES of C343 indicates that it is located primarily in the peripheral corona region.
Bayesian Finite Markov Mixture Model for Temporal Multi‐Tissue Polygenic Patterns
Authors: Liang Yulan , Kelemen Arpad
Published: February 2009

Finite mixture models can provide the insights about behavioral patterns as a source of heterogeneity of the various dynamics of time course gene expression data by reducing the high dimensionality and making clear the major components of the underlying structure of the data in terms of the unobservable latent variables. The latent structure of the dynamic transition process of gene expression changes over time can be represented by Markov processes. This paper addresses key problems in the analysis of large gene expression data sets that describe systemic temporal response cascades and dynamic changes to therapeutic doses in multiple tissues, such as liver, skeletal muscle, and kidney from the same animals. Bayesian Finite Markov Mixture Model with a Dirichlet Prior is developed for the identifications of differentially expressed time related genes and dynamic clusters. Deviance information criterion is applied to determine the number of components for model comparisons and selections. The proposed Bayesian models are applied to multiple tissue polygenetic temporal gene expression data and compared to a Bayesian model‐based clustering method, named CAGED. Results show that our proposed Bayesian Finite Markov Mixture model can well capture the dynamic changes and patterns for irregular complex temporal data (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Robust Joint Modeling of Longitudinal Measurements and Competing Risks Failure Time Data
Authors: Li Ning , Elashoff Robert M. , Li Gang
Published: February 2009

Existing methods for joint modeling of longitudinal measurements and survival data can be highly influenced by outliers in the longitudinal outcome. We propose a joint model for analysis of longitudinal measurements and competing risks failure time data which is robust in the presence of outlying longitudinal observations during follow‐up. Our model consists of a linear mixed effects sub‐model for the longitudinal outcome and a proportional cause‐specific hazards frailty sub‐model for the competing risks data, linked together by latent random effects. Instead of the usual normality assumption for measurement errors in the linear mixed effects sub‐model, we adopt a t ‐distribution which has a longer tail and thus is more robust to outliers. We derive an EM algorithm for the maximum likelihood estimates of the parameters and estimate their standard errors using a profile likelihood method. The proposed method is evaluated by simulation studies and is applied to a scleroderma lung study (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Global Tests for Linkage
Authors: Galta Rachid el , van Houwelingen Hans C. , Houwing‐Duistermaat Jeanine J.
Published: February 2009

To test for global linkage along a genome or in a chromosomal region, the maximum over the marker locations of mean alleles shared identical by descent of affected relative pairs, Zmax, can be used. Feingold et al. (1993) derived a Gaussian approximation to the distribution of the Zmax. As an alternative we propose to sum over the observed marker locations along the chromosomal region of interest. Two test statistics can be derived. (1) The likelihood ratio statistic (LR) and (2) the corresponding score statistic. The score statistic appears to be the average mean IBD over all available marker locations. The null distribution of the LR and score tests are asymptotically a 50: 50 mixture of chi‐square distributions of null and one degree of freedom and a normal distribution, respectively.

We compared empirically the type I error and power of these two new test statistics and Zmax along a chromosome and in a candidate region. Two models were considered, namely (1) one disease locus and (2) two disease loci. The new test statistics appeared to have reasonable type I error. Along the chromosome, for both models we concluded that for very small effect sizes, the score test has slightly more power than the other test statistics. For large effect sizes, the likelihood ratio statistic was comparable to and sometimes performed better than Zmax and both test statistics performed much better than the score test. For candidate regions of about 30 cM, all test statistics were comparable when only one disease‐locus existed and the score and likelihood ratio statistics had somewhat better power than Zmax when two disease loci existed (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Direct magnetic separation of immune cells from whole blood using bacterial magnetic particles displaying protein G
Authors: Takahashi Masayuki , Yoshino Tomoko , Takeyama Haruko , Matsunaga Tadashi
Published: February 2009

Direct separation of target cells from mixed population, such as peripheral blood, umbilical cord blood, and bone marrow, is an essential technique for various therapeutic or diagnosis applications. In this study, novel particles were fabricated, and direct magnetic separation of immune cells from whole blood using such particles was performed. The magnetotactic bacterium Magnetospirillum magneticum AMB‐1 synthesizes intracellular bacterial magnetic particles (BacMPs), and protein G was expressed on the surface of the BacMPs by gene fusion techniques with anchor proteins isolated from BacMP membrane. The BacMPs displaying protein G (protein G‐BacMPs) had high binding capabilities to a wide range of antibody types, and various versions of protein G‐BacMPs binding with different anti‐CD monoclonal antibodies were constructed. Consequently, direct magnetic separation of immune cells from whole blood using protein G‐BacMPs binding with anti‐CD monoclonal antibodies was demonstrated. B lymphocytes (CD19+ cells) or T lymphocytes (CD3+ cells), which represent less than 0.05% in whole blood cells, were successfully separated at a purity level of more than 96%. This level was superior to that from previous reports using other magnetic separation approaches. The results of this study demonstrate the utility of protein G‐BacMP and this particle may become a powerful tool for various therapeutic or diagnosis applications. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009
Scalable culture and cryopreservation of human embryonic stem cells on microcarriers
Authors: Nie Ying , Bergendahl Veit , Hei Derek J. , Jones Jeffrey M. , Palecek Sean P.
Published: February 2009

As a result of their pluripotency and potential for unlimited self‐renewal, human embryonic stem cells (hESCs) hold tremendous promise in regenerative medicine. An essential prerequisite for the widespread application of hESCs is the establishment of effective and efficient protocols for large‐scale cell culture, storage, and distribution. At laboratory scales hESCs are cultured adherent to tissue culture plates; these culture techniques are labor‐intensive and do not scale to high cell numbers. In an effort to facilitate larger scale hESC cultivation, we investigated the feasibility of culturing hESCs adherent to microcarriers. We modified the surface of Cytodex 3 microcarriers with either Matrigel or mouse embryonic fibroblasts (MEFs). hESC colonies were effectively expanded in a pluripotent, undifferentiated state on both Matrigel‐coated microcarriers and microcarriers seeded with a MEF monolayer. While the hESC expansion rate on MEF‐microcarriers was less than that on MEF‐plates, the doubling time of hESCs on Matrigel‐microcarriers was indistinguishable from that of hESCs expanded on Matrigel‐coated tissue culture plates. Standard hESC cryopreservation methodologies are plagued by poor viability and high differentiation rates upon thawing. Here, we demonstrate that cryopreservation of hESCs adherent to microcarriers in cryovials provides a higher recovery of undifferentiated cells than cryopreservation of cells in suspension. Together, these results suggest that microcarrier‐based stabilization and culture may facilitate hESC expansion and storage for research and therapeutic applications. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009
C. botulinum inactivation kinetics implemented in a computational model of a high‐pressure sterilization process
Authors: Juliano Pablo , Knoerzer Kai , Fryer Peter J. , Versteeg Cornelis
Published: February 2009

High‐pressure, high‐temperature (HPHT) processing is effective for microbial spore inactivation using mild preheating, followed by rapid volumetric compression heating and cooling on pressure release, enabling much shorter processing times than conventional thermal processing for many food products. A computational thermal fluid dynamic (CTFD) model has been developed to model all processing steps, including the vertical pressure vessel, an internal polymeric carrier, and food packages in an axis‐symmetric geometry. Heat transfer and fluid dynamic equations were coupled to four selected kinetic models for the inactivation of C. botulinum; the traditional first‐order kinetic model, the Weibull model, an nth‐order model, and a combined discrete log‐linear nth‐order model. The models were solved to compare the resulting microbial inactivation distributions. The initial temperature of the system was set to 90°C and pressure was selected at 600 MPa, holding for 220 s, with a target temperature of 121°C. A representation of the extent of microbial inactivation throughout all processing steps was obtained for each microbial model. Comparison of the models showed that the conventional thermal processing kinetics (not accounting for pressure) required shorter holding times to achieve a 12D reduction of C. botulinum spores than the other models. The temperature distribution inside the vessel resulted in a more uniform inactivation distribution when using a Weibull or an nth‐order kinetics model than when using log‐linear kinetics. The CTFD platform could illustrate the inactivation extent and uniformity provided by the microbial models. The platform is expected to be useful to evaluate models fitted into new C. botulinum inactivation data at varying conditions of pressure and temperature, as an aid for regulatory filing of the technology as well as in process and equipment design. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009
The meaning of style? Style reflexivity among Danish high school youths
Authors: Kjeldgaard Dannie
Published: February 2009

In much of the cultural theory literature on youth, style has been said to have started as an expression of subcultural class and transformed into individualized identity projects in neo‐tribal sociality. This article discusses young, Danish consumers' discourses on style and style practice. The key characteristic of their style practice is the reflexivity they bring to bear on their negotiation of global style expression in local identity projects. This style reflexivity manifests itself in two themes: style switching and style code reflexivity. The article shows that consumers' reflexivity of style consumption constitutes not only a ‘folk theory’ of consumption that reflects the academic and popular vernacular of style, but also postmodern consumer research scholarship's mode of expression about style. How individual consumers handle style in a reflexive manner through folk theories of the market is unexplored in previous research on the consumption of style.

Copyright © 2009 John Wiley & Sons, Ltd.
Sortase‐Mediated Ligation: A Gift from Gram‐Positive Bacteria to Protein Engineering
Authors: Tsukiji Shinya , Nagamune Teruyuki
Published: February 2009

A new enzymatic protein ligation tool, sortase, has recently emerged from Gram‐positive bacteria. This article outlines the technique, sortase‐mediated ligation, and its applications in protein engineering, which include the introduction of unnatural molecules into proteins, protein immobilization, protein–protein conjugation, protein cyclization, as a self‐cleavable tag for protein expression, protein–PNA hybrids, neoglycoconjugates, and cell‐surface protein labeling, etc.

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Batchwise and Continuous Organophilic Nanofiltration of Grubbs‐Type Olefin Metathesis Catalysts
Authors: Schoeps Dirk , Buhr Kristian , Dijkstra Marga , Ebert Katrin , Plenio Herbert
Published: February 2009

Retained: An N‐heterocyclic carbene with eight cyclohexyl groups (see figure) provides increased electron density for a highly active olefin metathesis catalyst as well as sufficient steric bulk to allow the efficient separation of such a complex from the organic products in the solvent‐resistant nanofiltration.

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A mass‐tagged N‐mesityl imidazolinium salt with four additional ‐CH2NCy2 substituents was synthesized, leading to a molecular mass of nearly 1100 g mol−1 in the corresponding carbene ligand. This mass‐tagged ligand was used to generate the respective Grubbs II and Grubbs–Hoveyda type complexes. The catalytic activity of the latter complex was tested in several olefin metathesis reactions and found to be slightly superior to that of the related N‐mesityl based complex. In batchwise solvent resistant nanofiltration experiments the ruthenium complex dissolved in toluene and following a metathesis reactions was efficiently retained (>99.8 %) by a single nanofiltration; the permeate contained less than 4 ppm of Ru. Equally efficient catalyst retention was observed in a membrane reactor utilized for the continuous synthesis of a RCM product.
ChemInform Abstract: Polar Domains and Charge‐Density Waves in the Acentric Cerium(III) Iron(II) Sulfide Ce22Fe21S54.
Authors: Mills Allison M. , Ruck Michael
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chromium‐Based Clinopyroxene‐Type Germanates NaCrGe2O6 and LiCrGe2O6 at 298 K.
Authors: Redhammer Guenther J. , Roth Georg , Amthauer Georg
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Crystal Structures of NiPdTe and Ni2PdSe2.
Authors: Bichler Daniel , Pocha Regina , Loehnert Catrin , Johrendt Dirk
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Characterization, and Sorption Properties of Amorphous Titanium Phosphate and Silica‐Modified Titanium Phosphates.
Authors: Maslova Marina V. , Rusanova Daniela , Naydenov Valeri , Antzutkin Oleg N. , Gerasimova Lidia G.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Crystal Structure, Infrared and Raman Spectra of Sr4Cu3(AsO4)2 (AsO3OH)4×3H2O and Ba2Cu4(AsO4)2 (AsO3OH)3.
Authors: Dordevic Tamara , Karanovic Ljiljana
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Separation of Diastereoisomeric 1‐Aryl‐3‐piperidino(morpholino)‐2‐phenylpropan‐1‐ols and Their Hydrochlorides.
Authors: Gevorgyan G. A. , Gasparyan N. K. , Agababyan A. G. , Panosyan G. A.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Functionalized Dialkyl Cyclobutane‐1,1‐dicarboxylates and Alkyl 5,6‐Dihydro‐4H‐pyran‐3‐carboxylates via Michael‐Induced Ring Closure of δ‐Chloro‐α,β‐Unsaturated Diesters and Ketoesters.
Authors: Mangelinckx Sven , Vermaut Bruno , Verhe Roland , De Kimpe Norbert
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Oxidation of Cyclic Sulfides Catalyzed by an Aluminum(salalen) Complex as the Catalyst.
Authors: Matsumoto Kazuhiro , Yamaguchi Tetsufumi , Katsuki Tsutomu
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Stereospecific Palladium‐Catalyzed Route to Monoalkyl Diazenes for Mild Allylic Reduction.
Authors: Movassaghi Mohammad , Ahmad Omar K.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Synthesis of 2,3,5‐Trichloro‐4,4‐dimethoxy‐ (IV) and 2,5‐Dichloro‐3,4,4‐trimethoxycyclopent‐2‐en‐1‐ones (III) from Hexachlorocyclopentadiene and Some Aspects of Their Reactivity.
Authors: Ivanova N. A. , Kislitsina K. S. , Miftakhov M. S.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Pot Synthesis of Fused Tricyclic Heterocycles with Quaternary Carbon Stereocenter by Sequential Pauson—Khand Reaction and Formal [3 + 3] Cycloaddition.
Authors: Fan Liyan , Zhao Wanxiang , Jiang Weihua , Zhang Junliang
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐Phospha[3]ferrocenophanes with Planar Chirality: Synthesis and Use in Enantioselective Organocatalytic [3 + 2] Cyclizations.
Authors: Voituriez Arnaud , Panossian Armen , Fleury‐Bregeot Nicolas , Retailleau Pascal , Marinetti Angela
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Reagent for Aldehyde to Alkyne Homologation.
Authors: Taber Douglass F. , Bai Sha , Guo Peng‐fei
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A General and Environmentally Benign Catalytic Reduction of Nitriles to Primary Amines.
Authors: Enthaler Stephan , Addis Daniele , Junge Kathrin , Erre Giulia , Beller Matthias
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium Hydride Catalyzed Addition of Aldehydes to Dienes Leading to β,γ‐Unsaturated Ketones.
Authors: Omura Sohei , Fukuyama Takahide , Horiguchi Jiro , Murakami Yuji , Ryu Ilhyong
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Synthesis of the Docetaxel (Taxotere) Side Chain: Organocatalytic Highly Enantioselective Synthesis of Esterification‐Ready α‐Hydroxy‐β‐amino Acids.
Authors: Dziedzic Pawel , Vesely Jan , Cordova Armando
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cobalt‐Catalyzed Regioselective Synthesis of Indenamine from o‐Iodobenzaldimine and Alkyne: Intriguing Difference to the Nickel‐Catalyzed Reaction.
Authors: Liu Chuan‐Che , Korivi Rajendra Prasad , Cheng Chien‐Hong
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural Aspects of Iodine‐Promoted One‐Pot Cyclization of σ‐Bis(methylthio)stilbenes to Thieno[3,2‐b]thiophene Derivatives: Synthetic Trials of Tetrathienoacenes from 1,2‐Bis(3‐methylthiothiophen‐2‐yl)ethenes.
Authors: Yamamoto Tatsuya , Miyazaki Eigo , Takimiya Kazuo
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regioselectivity in the Reactions of N‐(Polychloroethylidene)sulfonamides with 1H‐Pyrrole and 1‐Methyl‐1H‐pyrrole.
Authors: Rozentsveig I. B. , Shainyan B. A. , Kondrashov E. V. , Rudyakova E. V. , Rozentsveig G. N. , Chernyshev K. A. , Levkovskaya G. G.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Enantioselective Friedel—Crafts Reaction of 4,7‐Dihydroindoles with β,γ‐Unsaturated α‐Keto Esters by Chiral Broensted Acids.
Authors: Zeng Mi , Kang Qiang , He Qing‐Li , You Shu‐Li
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Aminophenols. Part 11. Synthesis of 3‐Arylideneindolin‐2‐ones from 2‐Aminophenols by Ugi Four‐Component Reaction and Heck Carbocyclization.
Authors: Dai Wei‐Min , Shi Jianyu , Wu Jinlong
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Studies on Antidepressant and Anticonvulsant Activities of Some 3‐(2‐Thienyl)pyrazoline Derivatives
Authors: Ozdemir Zuhal , Kandilci H. Burak , Gumusel Bulent , Calis Unsal , Bilgin A. Altan
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a New Class of 2‐Oxazolines and 2‐Thiazolines
Authors: Padmaja A. , Payani T. , Mahesh K.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐Nitrosobenzothiazoles: Useful Synthons for New Azobenzothiazole Dyes.
Authors: Faustino Helio , El‐Shishtawy Reda M. , Reis Lucinda V. , Santos Paulo F. , Almeida Paulo
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New 1‐Substituted 4‐Perfluoroalkyl Tetrazol‐5‐ones
Authors: Mekni Nejib , Baklouti Ahmed
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐Alkylidene‐1,3‐dithiane Monoxides as Activated Alkenes in Rhodium‐Catalyzed Addition Reaction of Arylboronic Acids.
Authors: Yoshida Suguru , Yorimitsu Hideki , Oshima Koichiro
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Preparation and Cope Rearrangement of 2‐CF3‐cis‐2,3‐Bis(alkenyl)oxiranes: A Facile Route to 2‐CF3‐Substituted Oxacycles.
Authors: Shimizu Masaki , Fujimoto Takuya , Liu Xinyu , Takeda Youhei , Hiyama Tamejiro
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Mercurophilic Properties of Dithiocrown Ethers Having an Azulene Pendant.
Authors: Kubo Kanji , Mori Akira , Nishimura Tatsuya , Kato Nobuo
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tellurium‐Containing Heterocycles. Part 26. A New One‐Pot Synthetic Method for Selenium‐Containing Medium‐Sized α,β‐Unsaturated Cyclic Ketones.
Authors: Sashida Haruki , Nakayama Akemi , Kaname Mamoru
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (+)‐Cassaine via Transannular Diels—Alder Reaction.
Authors: Phoenix Serge , Reddy Maddi Sridhar , Deslongchamps Pierre
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Second Generation Formal Synthesis of (‐)‐Cephalotaxine.
Authors: Hameed Abdul , Blake Alexander J. , Hayes Christopher J.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: First Total Synthesis of (.+‐.)‐Powelline.
Authors: Anwar Hany F. , Hansen Trond Vidar
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Benzaldehyde Derivatives from Eurotium rubrum, an Endophytic Fungus Derived from the Mangrove Plant Hibiscus tiliaceus.
Authors: Li Dong‐Li , Li Xiao‐Ming , Li Tie‐Gang , Dang Hong‐Yue , Proksch Peter , Wang Bin‐Gui
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Coumarins from the Chinese Drug Qianhu. Part 27. Structure of a New Simple Coumarin Glycoside from Bai‐Hua Qianhu, Peucedanum praeruptorum.
Authors: Ishii Hirotaka , Okada Yoshihito , Baba Masaki , Okuyama Toru
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 8′‐Hydroxyzearalanone (I) and 2′‐Hydroxyzearalanol (II): Resorcyclic Acid Lactone Derivatives from the Marine‐Derived Fungus Penicillium sp.
Authors: Yang Xiudong , Khong Trung Thang , Chen Li , Choi Hong Dae , Kang Jung Sook , Son Byeng Wha
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Synthesis of Bisubstrate Inhibitors of Type 1 17β‐Hydroxysteroid Dehydrogenase: Overview and Perspectives
Authors: Fournier D. , Poirier D. , Mazumdar M. , Lin S.‐X.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N‐Alk‐1‐enylhydroxylamines
Authors: Collier S. J.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbon Monoxide as a Reagent — The Role of N‐Heterocyclic Carbene (NHC) Ligands in Metal‐Catalyzed Carbonylation Reactions
Authors: Veige Adam S.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Propargylic Substitution of the Hydroxyl Group in Propargylic Alcohols
Authors: Kabalka George W. , Yao Min‐Liang
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Green Oxidation of Alcohols Using Biomimetic Cu Complexes and Cu Enzymes as Catalysts
Authors: Arends Isabel W. C. E. , Gamez Patrick , Sheldon Roger A.
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nucleotides and Nucleic Acids: Oligo‐ and Polynucleotides
Authors: Loakes David
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemoselective Neoglycosylation
Authors: Nicotra Francesco , Cipolla Laura , Peri Francesco , La Ferla Barbara , Redaelli Cristina
Published: February 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Intravenous verapamil therapy in imminent myocardial infarction
Authors: Hasin Y. , Freiman I. , Schwarz T. , Weiss A. T. , Gotsman M. S.
Published: February 2009

We studied 16 patients with small myocardial infarction who had further episodes of chest pain with ST‐segment elevation, a sign of transmural myocardial ischemia and imminent infarction extension. Coronary angiography in 14 showed a critical lesion in 13. Intravenous verapamil abolished chest pain and ST‐segment elevation. It caused a fall in right atrial and left ventricular end‐diastolic pressures (LVEDP) and cardiac output, reflex systemic vasoconstriction, and a rise in systemic vascular resistance. There was no reflex tachycardia. Volume expansion raised LVEDP and restored a normal cardiac output. Accelerated junctional rhythm with isorhythmic A‐V dissociation occurred in 5 patients. Two patients sustained a transmural infarction, 10 underwent coronary artery bypass grafting, and 4 are symptom‐free with oral treatment. Intravenous treatment was an effective method of treating acute episodes of transmural myocardial ischemia and preventing their recurrence in patients with critical coronary artery narrowing. Continuous verapamil infusion stabilized the patients' condition and enabled smooth coronary angiography and induction of anesthesia for surgery.
Transseptal left heart catheterization: A review of 278 studies
Authors: B‐Lundqvist C. , Olsson S. B. , Varnauskas E.
Published: February 2009

In our laboratory, we performed 278 transseptal left heart catheterizations in adult patients over a period of 13 years. The left atrium was entered in 91.4% of the intended left heart catheterizations. Of 252 attempts, the left ventricle was entered in 96.1 %. Major complications were aortic puncture (0.7%), pericardial puncture/suspected tamponade (3.2%), systemic arterial embolism (1.1%), and suspected perforation of the inferior vena cava (0.4%). There were no deaths. Although less frequently performed during the last decade, the transseptal catheterization technique has a complication rate of the same magnitude as during periods when this method was more commonly applied.
Coronary artery perforation during coronary angioplasty
Authors: Grollier G. , Bories H. , Commeau P. , Foucault J. P. , Potier J. C.
Published: February 2009

In one patient percutaneous transluminal coronary angioplasty was complicated by coronary artery perforation of the left anterior descending coronary artery with light pericardial effusion. The outcome was favorable without either pericardiocentesis or emergency surgery.
Sinoatrial block induced by oral diltiazem
Authors: Imamura T. , Koiwaya Y. , Nakamura M.
Published: February 2009

A 58‐year‐old man with variant angina who had no history suggestive of sinus node dysfunction experienced palpitation with pulse deficit after 8 days of diltiazem treatment, 240 mg per day. Electrocardiogram (ECG) revealed frequent occurrence of sinoatrial block. After discontinuation of diltiazem, an ambulatory ECG demonstrated gradual reduction of the occurrence of sinoatrial block, and no recurrence 8 hours after the last dose of the drug. One should note that diltiazem induces not only sinus node suppression and atrioventricular conduction disturbance, but also sinoatrial block.
Noninvasive assessment of indomethacin therapy in patent ductus arteriosus in preterm infants
Authors: Kashani I. A. , Nulton G. D. , Sahn D. J.
Published: February 2009

We performed 138 serial two‐dimensional (2‐D), M‐mode, and Doppler echocardiographic studies to assess the efficacy of intravenous indomethacin (INDO) therapy for patent ductus arteriosus (PDA) in 41 preterm infants. Nine infants expired without sufficient echo data to warrant inclusion in the study. Of the remaining 32 infants, 12 (Group 1) required ligation despite INDO therapy, 18 (Group 2) responded to INDO or spontaneously closed their PDAs, and 2 were transferred to other hospitals with their PDAs still open and were lost to followup. The presence of PDA was verified by 2‐D echo vizualization of the ductus (high parasternal short‐axis views) and Doppler demonstration of high velocity ductal flow toward the main pulmonary artery. The ratio of PDA lumen to aortic root inner diameter (Ao) was measured as well. Indication for surgical ligation was failure of the PDA to close after 3 or more courses of INDO. In Group 1, the PDA/Ao ratio was 0.45±0.10 standard error of the mean (SEM) pre‐INDO, and 0.40±0.12 SEM post‐INDO (immediately before ligation). In Group 2, the PDA/Ao ratio was 0.42±0.11 SEM pre‐INDO, and 0.19±0.14 SEM at the end of INDO course (p<0.001), with 12 infants showing no ductal flow by Doppler. Follow‐up six months after INDO therapy has shown no residual murmurs or other evidence of PDA in any INDO‐closed infant. Five of the 18 infants have undergone repeated echocardiographic studies, all of which were negative for PDA patency or flow. It is concluded that the combination of 2‐D echo and Doppler studies and to some extent, PDA/Ao ratio are a fairly reliable means for assessing the efficacy of therapy and patency of ductus arteriosus.
Radionuclide left ventricular function curve during atrial pacing in normal subjects and in patients with coronary artery disease
Authors: Rozenman Y. , Weiss A. T. , Gotsman M. S.
Published: February 2009

We used radionuclide angiography during right atrial pacing to assess left ventricular function in 7 normal subjects and 20 patients with coronary artery disease. A left ventricular function curve relating stroke volume to end‐diastolic volume was plotted for each patient. The normal pacing ventricular function curve was a straight line passing through the origin of axes. The pacing ventricular function curve was abnormal in 18 of the 20 patients with coronary artery disease, and three different shaped curves were obtained, reflecting decreased contractile force for the same end‐diastolic volume during ischemia. Cardiac output and blood pressure do not change during atrial pacing, thus the Frank‐Starling relationship is evaluated by this method during almost experimentally controlled conditions. Relating stroke volume to end‐diastolic volume, and not end‐diastolic pressure, distinguishes between overall left ventricular systolic function and left ventricular compliance.
Nonprogression of coronary artery atherosclerosis in homozygous familial hypercholesterolemia after 31 months of repetitive plasma exchange
Authors: Stein E. A. , Adolph R. , Rice V. , Glueck C. J. , Spitz H. B.
Published: February 2009

The effects of plasma exchange performed every two weeks for 31 months in combination with diet and drug therapy were studied in a patient with receptor‐defective homozygous familial hypercholesterolemia. Coronary angiography performed three years prior to commencing plasma exchange was compared to angiography 31 months after starting the program. Comparison of the angiograms taken six years apart showed no progression of coronary atheroma in the main left coronary artery in which a 30% narrowing was originally seen. An internal mammary artery‐coronary artery bypass remained widely patent and showed no development of atherosclerosis. Plasma cholesterol levels were reduced 46% by plasma exchange, diet and drug compared to diet and drug alone. Achilles tendon xanthoma diminished significantly. It appears that plasma exchange combined with diet and drug therapy, while not producing regression of existing atheromatous lesions, does retard or prevent further progression.
Progression of myocardial dysfunction in asymptomatic patients with severe aortic insufficiency
Authors: Scognamiglio R. , Fasoli G. , Dalla VOLTA S.
Published: February 2009

By serial echocardiographic examinations, we investigated the parameters predictive of left ventricular (LV) deterioration in 38 asymptomatic patients with severe aortic insufficiency (AI). Based on their first echocardiograms, patients were divided into two groups: Group 1 (n = 30) had normal fractional shortening (FS); Group 2 (n = 8) had abnormal FS. Similar values of LV end‐diastolic, end‐systolic dimension (EDD, ESD), FS, radius/thickness ratio, and mean wall stress characterized stable and unstable patients of Group 1; unstable patients, who developed abnormal values of FS during the follow‐up, showed significantly lower values of the contractility index (peak arterial pressure/end‐systolic volume ratio, PAP/ESV). The unstable patients, moreover, were distributed near the onset of the downslope and moved along the descending limb of the curvilinear pump performance‐myocardial contractility relation. No changes occurred in Group 2 patients during follow‐up. Three unstable Group 1 patients and the 8 patients of Group 2 underwent aortic valve replacement (AVR): postoperative EDD was less than 65 mm and the changes from before to after AVR were greater than 11 mm in all cases. We conclude that the pump performance‐myocardial contractility relation visualized the unstability of LV function in asymptomatic patients and that AVR can be delayed after the appearance of an abnormal FS for at least 36 months.