bluuebunny/crossref_metadata_2025 huggingface dataset:
Nitric Oxide-cGMP Signaling in Hypertension
Authors: Ataei Ataabadi Ehsan , Golshiri Keivan , Jüttner Annika , Krenning Guido , Danser A.H. Jan , Roks Anton J.M.
Published: August 2020

For the treatment of systemic hypertension, pharmacological intervention in nitric oxide-cyclic guanosine monophosphate signaling is a well-explored but unexploited option. In this review, we present the identified drug targets, including oxidases, mitochondria, soluble guanylyl cyclase, phosphodiesterase 1 and 5, and protein kinase G, important compounds that modulate them, and the current status of (pre)clinical development. The mode of action of these compounds is discussed, and based upon this, the clinical opportunities. We conclude that drugs that directly target the enzymes of the nitric oxide-cyclic guanosine monophosphate cascade are currently the most promising compounds, but that none of these compounds is under investigation as a treatment option for systemic hypertension.
Observing the World as Dancers Do: Teaching Dance to Medical Students
Authors: Rogers Catherine , Leventhal David , Apple Leah , Kostro Katrina , Sudler Andrew , Charon Rita
Published: August 2020

On a sunny day in a studio overlooking the Hudson River, a Mark Morris dancer guides a group of medical students in choreographing their patients’ stories. This class in narrative medicine provides a safe laboratory where doctors-to-be learn to view their relationships with future patients as an improvisatory partnered dance in which the choreography adjusts moment to moment as new challenges, details, and possibilities for healing emerge.
Framing Black Labor: On Archives and Mine Dancing in South African Gold Mines, 1950–1970
Authors: Charlson Doria E.
Published: August 2020

Promoted as a tourist attraction to highlight the benevolent treatment of black migrant laborers at South African gold mines, mine dance performances by workers became a symbol of both “authentic” preindustrial African culture and, paradoxically, the progress made towards industrializing the nation. Excavating both state-sponsored, industrial archives and the photographs of black South African Ernest Cole enables a reframing of the ways dance was mobilized and extracted during apartheid.
Sensory Excess: The London Premiere of Confessions
Authors: Luck Neil
Published: August 2020

Spatial Opera Company’s original work Confessions is an internationally acclaimed collaborative performance work that surrounds a blindfolded audience, employing spatialized sound and music in a reverberant natural acoustic to stimulate a heightened, imaginative response.
LLAP Band Structure and Intense Lake-Effect Snowfall Downwind of Lake Ontario: Insights from the OWLeS 7–9 January 2014 Event
Authors: Bergmaier Philip T. , Geerts Bart
Published: August 2020

Modeling and observational studies stemming from the 2013–14 Ontario Winter Lake-Effect Systems (OWLeS) field campaign have yielded much insight into the structure and development of long-lake-axis-parallel (LLAP) lake-effect systems over Lake Ontario. This study uses airborne single- and dual-Doppler radar data obtained during two University of Wyoming King Air flights, as well as a high-resolution numerical model simulation, to examine and contrast two distinctly different LLAP band structures observed within a highly persistent lake-effect system on 7–9 January 2014. On 7 January, a very cold air mass accompanied by strong westerly winds and weak capping aloft resulted in a deep, intense LLAP band that produced heavy snowfall well inland. In contrast, weaker winds, weaker surface heat fluxes, and stronger capping aloft resulted in a weaker LLAP band on 9 January. This band was blocked along the downwind shore and produced only light snowfall closer to the shoreline. Although the two structures examined here represent opposite ends of a spectrum of LLAP bands, both cases reveal a well-organized mesoscale secondary circulation composed of two counterrotating horizontal vortices positioned on either side of a narrow updraft within the band. In both cases, this circulation traces back to a shallow, baroclinic land-breeze front originating along a bulge in the lake’s southern shoreline. As the band extends downstream and the low-level baroclinity weakens, buoyancy increases within the band—driven in part by cloud latent heating—leading to band intensification and a deeper, stronger, and more symmetric secondary circulation over the lake.
WRF Modeling of Deep Convection and Hail for Wind Power Applications
Authors: Letson F. , Shepherd T. J. , Barthelmie R. J. , Pryor S. C.
Published: August 2020

Deep convection and the related occurrence of hail, intense precipitation, and wind gusts represent a hazard to a range of energy infrastructure including wind turbine blades. Wind turbine blade leading-edge erosion (LEE) is caused by the impact of falling hydrometeors onto rotating wind turbine blades. It is a major source of wind turbine maintenance costs and energy losses from wind farms. In the U.S. southern Great Plains (SGP), where there is widespread wind energy development, deep convection and hail events are common, increasing the potential for precipitation-driven LEE. A 25-day Weather Research and Forecasting (WRF) Model simulation conducted at convection-permitting resolution and using a detailed microphysics scheme is carried out for the SGP to evaluate the effectiveness in modeling the wind and precipitation conditions relevant to LEE potential. WRF output for these properties is evaluated using radar observations of precipitation (including hail) and reflectivity, in situ wind speed measurements, and wind power generation. This research demonstrates some skill for the primary drivers of LEE. Wind speeds, rainfall rates, and precipitation totals show good agreement with observations. The occurrence of precipitation during power-producing wind speeds is also shown to exhibit fidelity. Hail events frequently occur during periods when wind turbines are rotating and are especially important to LEE in the SGP. The presence of hail is modeled with a mean proportion correct of 0.77 and an odds ratio of 4.55. Further research is needed to demonstrate sufficient model performance to be actionable for the wind energy industry, and there is evidence for positive model bias in cloud reflectivity.
Skillful All-Season S2S Prediction of U.S. Precipitation Using the MJO and QBO
Authors: Nardi Kyle M. , Baggett Cory F. , Barnes Elizabeth A. , Maloney Eric D. , Harnos Daniel S. , Ciasto Laura M.
Published: August 2020

Although useful at short and medium ranges, current dynamical models provide little additional skill for precipitation forecasts beyond week 2 (14 days). However, recent studies have demonstrated that downstream forcing by the Madden–Julian oscillation (MJO) and quasi-biennial oscillation (QBO) influences subseasonal variability, and predictability, of sensible weather across North America. Building on prior studies evaluating the influence of the MJO and QBO on the subseasonal prediction of North American weather, we apply an empirical model that uses the MJO and QBO as predictors to forecast anomalous (i.e., categorical above- or below-normal) pentadal precipitation at weeks 3–6 (15–42 days). A novel aspect of our study is the application and evaluation of the model for subseasonal prediction of precipitation across the entire contiguous United States and Alaska during all seasons. In almost all regions and seasons, the model provides “skillful forecasts of opportunity” for 20%–50% of all forecasts valid weeks 3–6. We also find that this model skill is correlated with historical responses of precipitation, and related synoptic quantities, to the MJO and QBO. Finally, we show that the inclusion of the QBO as a predictor increases the frequency of skillful forecasts of opportunity over most of the contiguous United States and Alaska during all seasons. These findings will provide guidance to forecasters regarding the utility of the MJO and QBO for subseasonal precipitation outlooks.
Modulation and mechanism of spatial structure for multi-layer cyanate ester resin composites to achieve remarkably increased energy storage density and decreased dielectric loss
Authors: Zhang Xiaobao , Yuan Li , Liang Guozheng , Gu Aijuan
Published: August 2020

Overcoming sticky problems of large dielectric loss and poor breakdown strength ( Eb) is prerequisite of actual applications for high dielectric constant polymer composites. Herein, three kinds of multi-layer structure composites with different spatial structures (2MP-CE/CNT, CE/CNT-2MP-CE/CNT, MP-CE/CNT-MP) were prepared based on carbon nanotubes (CNTs), cyanate ester (CE) resin and mica paper (MP). Compared with traditional single-layer CE/CNT composite, multi-layer CE/CNT-2MP-CE/CNT composites, of which the middle layer is two pieces of MPs with a thickness of 60 µm, while both bottom and top layers are CE/CNT composite, simultaneously achieve 105 reduction in dielectric loss and 18.1 times increase in energy storage density ( Ue). Through modulating two sheets of MPs and CE/CNT as top and bottom layer, respectively, 2MP-CE/CNT composite with 60 μm MPs has the largest breakdown strength ( Eb), its Eb and Ue are severally about 7.1 and 19.5 times of those of CE/CNT composite. The relationship and mechanism between spatial structure and integrated performance such as dielectric properties, Eb and Ue of composites were systematically investigated. The attractive integrated performances of CE/CNT-2MP-CE/CNT and 2MP-CE/CNT composites are attributed to their unique composition and spatial structures, which bring special micro-capacitance and interfacial polarization, and thus leading to outstanding performances. Therefore, this investigation provides a strategy for getting desirable performances through building composites with specific spatial structure.
Perception of Medical Assistance in Dying Among Asian Buddhists Living in Montreal, Canada
Authors: Dorji Nidup , Lapierre Sylvie , Dransart Dolores Angela Castelli
Published: August 2020

In the Western world including Canada, grievous and irredeemable health conditions, which cause unbearable suffering, has given support to the legalization of medical aid in dying (MAiD). It is unknown how Asian Buddhists who are in contact with the Western culture perceive MAiD. In this qualitative study, 16 Asian Buddhists living in Montreal took part in a semi-structured interview. Contrary to general findings in the literature, religious affiliation do not always determine moral stances and practical decisions when it comes to MAiD. Some participants were willing to take some freedom with the doctrine and based their approval of MAiD on the right to self-determination. Those who disapproved the use of MAiD perceived it as causing unnatural death, creating bad karma, and interfering with a conscious death. End-of-life (EoL) care providers have to remain sensitive to each patient’s spiritual principles and beliefs to understand their needs and choices for EoL care.
Effects of porosity and area density on upward flame spread characteristics over thin flax fabric
Authors: Gao Yunji , Zhu Hui , Zhang Yuchun , Zhu Guoqing , Chai Guoqiang
Published: August 2020

Few investigations have systematically addressed the porosity effects of upward flame spread over fabric fuels, although the porosity is a special property for fabric fuels. The present paper studies the porosity and area density effects on upward flame spreading using 160.0 cm tall and 8.0 cm wide flax fabric samples with various porosities and area densities. The flame shape, flame length, flame spread rate, ignition time, standoff distance and surface temperature distribution are obtained and analyzed. The major findings are summarized as follows: as the porosity increases and corresponding area density declines, the flame spread rate and flame length increase, whereas the ignition time decreases, which is because the oxygen can reach the fuel surface in the pyrolysis region more easily and, subsequently, the heat flux received by the virgin fuels increases. The two parameters of flame standoff distance and surface temperature in the preheating region can be applied to characterize the heat flux received by the virgin fuels. Generally, when the porosity increases and the corresponding area density decreases, the flame standoff distance and the surface temperature at the same distance from pyrolysis front increase, which reveals that the heat flux received by the virgin surface increases.
Trajectories of Depression and Their Predictors in a Population-Based Study of Korean Older Adults
Authors: Lim Hyun Ja , Cheng Yanzhao , Kabir Rasel , Thorpe Lilian
Published: August 2020

The aim of this study was to determine trajectories of depression in older adults and to identify predictors of membership in the different trajectory groups. A total of 3983 individuals aged 65 or older were included. Latent class growth models were used to identify trajectory groups. Of 3983 individuals, 2269 (57%) were females, with a mean baseline age of 72.4 years ( SD = 6 years). Four depression trajectories were identified across 8 years of follow-up: “low-flat” ( n = 3636; 86.6%), “low-to-middle” ( n = 214; 9.2%), “low-to-high” ( n = 31; 1.3%), and “high-stable” ( n = 102; 2.9%). Compared to the low-flat depression group, high-stable depression group members were more likely to be female, have three or more chronic diseases, and were more likely not to own a home. Our findings will assist health policy decision-makers in planning intervention programs targeting those most likely to experience persistent depression in order to improve psychological well-being in the elderly.
Location Matters: Disparities in the Likelihood of Receiving Services in Late Life
Authors: Weaver Raven H. , Roberto Karen A.
Published: August 2020

Moving beyond typical dichotomous rural–urban categorizations, this study examines older adults’ likelihood of receiving home- and community-based services. Data from 1608 individuals aged 60+ who requested assistance from Area Agencies on Aging in Virginia in 2014–2015 were analyzed; 88% of individuals received at least one service. Receiving services was associated with geographic-based factors. Individuals living in completely rural areas were significantly less likely to receive any service compared to individuals in mostly rural (OR = 2.46, p = .003) and mostly urban (OR = 1.97, p = .024) areas. There were subtle but significant geographic-based differences in the likelihood of receiving specific services including food/meal, fresh food, information and referral, in-home care, utilities support, and transportation. Findings provide nuanced insights about geographic-based disparities in the receipt of services and suggest the need for new and modified service delivery strategies that maximize older adults’ ability to live.
So What Exactly Is a “Coalition” Within an Organization? A Review and Organizing Framework
Authors: Mithani Murad A. , O’Brien Jonathan P.
Published: August 2020

An organizational coalition consists of individuals who, despite their persistent differences, work together to pursue a mutually beneficial goal. While central to the political view of the firm, the research on organizational coalitions has evoked diverse characterizations of its members, their relationship with the rest of the organization, and how coalitions balance conflicts and compromise. The result is a fragmented literature that has limited the theoretical clarity necessary to appreciate one of the most important forms of collective political influence in organizations. Drawing on six decades of research, we offer a systematic review of organizational coalitions. We anchor our review on the actors who are party to a coalition, the structures that characterize the boundaries of a coalition, and the processes that lead to a coalition’s influence. This synthesis reveals significant overlaps with regard to the definition of actors, their structural positions, and the perpetual nature of conflict and negotiations. Yet we also note significant divergence in the interactions between actors, how the structure of a coalition maps onto that of an organization, and the processes that affect a coalition’s bargaining position and outcomes. These divergences reveal six distinct streams of research. Using our actor-structure-process model, we organize these research streams into a framework that identifies the diverse conceptualizations as contextual and reconcilable manifestations of a common underlying construct, thus yielding a dynamic model of organizational coalitions. Building on this framework, we propose an agenda for future research.
Intimate Partner Violence Forgiveness Dynamics in the Context of Men’s Positions as Victims and Perpetrators: A Dyadic Perspective
Authors: Zrihan Weitzman A. , Buchbinder E.
Published: August 2020

Recent years have seen increased awareness of the need to understand forgiveness in the context of intimate partner violence (IPV). The present qualitative study focused on how male batterers and female victims perceived and interacted with forgiveness. The study was based on in-depth semi-structured interviews with 15 spouses who had been married for between 4 and 30 years. The study findings show that the male batterers perceived forgiveness confusingly out of their dual self-perception as both perpetrator and victim. However, whether as perpetrator or victim, they clung to the position of forgiver. This dual perception blurred the spouses’ perpetrator and victim roles as well as the gap between seeking and granting forgiveness. Both spouses tended to be trapped in their own self-perception as forgiver and hence, the issue of forgiveness preserved the status quo in the relationship and the preservation of power experience.
Mirror therapy simultaneously combined with electrical stimulation for upper limb motor function recovery after stroke: a systematic review and meta-analysis of randomized controlled trials
Authors: Saavedra-García Alberto , Moral-Munoz Jose A , Lucena-Anton David
Published: August 2020

Objective:

To evaluate the current evidence on the effectiveness of simultaneous combination of mirror therapy and electrical stimulation in the recovery of upper limb motor function after stroke, compared with conventional therapy, mirror therapy or electrical stimulation isolated.

Data sources:

Articles published in PubMed, Web of Science, Scopus, Physiotherapy Evidence Database (PEDro), Cochrane Central register of controlled trials and ScienceDirect up to July 2020.

Review methods:

The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed. Methodological quality was assessed using the PEDro tool. The RevMan 5.4 statistical software was used to obtain the meta-analysis, through the standardized mean difference and 95% confidence intervals (CI), and to evaluate the risk of bias. The GRADE approach was employed to assess the certainty of evidence.

Results:

Eight articles were included in this systematic review, seven were included in the meta-analysis. A total of 314 participants were analyzed. The overall quality of the articles included in this review was good. There was no overall significant mean difference on upper limb motor function after stroke using the Upper-Extremity Fugl-Meyer Assessment by 1.56 (95% CI = –2.08, 5.20; P = 0.40; moderate-certainty evidence) and the Box and Block Test results by 1.39 (95% CI = –2.14, 4.92; P = 0.44; high-certainty evidence). There was overall significant difference in the Action Research Arm Test by 3.54 (95% CI = 0.18, 6.90; P = 0.04; high-certainty evidence).

Conclusion:

Direct scientific evidence about the effectiveness of the combined therapy of mirror therapy and electrical stimulation simultaneously for the improvement of the upper limb motor function after stroke is lacking. Further high-quality and well-designed research is needed.
Mixed adenoneuroendocrine carcinoma (MANEC) of the ampulla of Vater in a Chinese patient: A case report
Authors: Li Xu , Li Dezhao , Sun Xiaodong , Lv Guoyue
Published: August 2020

Mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumour of the gastrointestinal tract with both epithelial and neuroendocrine components. We describe a case of a 57-year-old man who presented with yellow sclera and dark urine. Contrast-enhanced computed tomography (CT) showed enlargement of the intra and extrahepatic bile ducts and a neoplastic lesion at the end of the common bile duct which was indistinguishable from the adjacent head of the pancreas and duodenum. A pancreaticoduodenectomy was performed and histopathological examination of resected samples showed that tumour was a complex lesion with adenocarcinoma and neuroendocrine components positive for neuroendocrine markers (chromogranin A and synaptophysin) with a Ki-67 labelling index of 40%. The patient was diagnosed with MANEC in the ampulla of Vater with a neuroendocrine carcinoma component of approximately 70%. Ampullary MANECs are highly aggressive tumours with a high risk for distant metastases and a poor prognosis. Therefore, establishing a standard therapeutic strategy is crucial.
A new case of myelodysplastic syndrome associated with t(3;3)(q21;q26) and inv(11)(p15q22)
Authors: Monti Valentina , Bagnoli Filippo , Bolli Niccolo’ , Vittoria Laura , Stioui Sabine , Moiraghi Maria Luisa , Pruneri Giancarlo , Testi Maria Adele
Published: August 2020

Introduction:

Myeloid malignancies are associated with a number of recurrent and sporadic rearrangements that may be oncogenic by ensuring growth advantage and/or increased survival. t(3;3)(q21;q26) has been recognized as a recurrent abnormality in myelodysplastic syndromes (MDS) with poor prognostic significance. Inversion of chr(11) engendering NUP98-DDX10 chimeric product is sporadic and usually associated with diseases with poor prognosis (therapy-related myeloid neoplasm). To date, these cytogenetic abnormalities have been described as isolated events.

Case description:

We report the first case of an 80-year-old man with high-risk MDS harboring a translocation t(3,3)(q21q26) jointly with an inv(11)(p15q22) detected by fluorescent in situ hybridization analysis and conventional cytogenetic techniques.

Conclusion:

A similar pattern of acquisition was never described before in MDS. The coexistence of two independent, high-risk oncogenic, rare events in the same clone suggests that there may be a functional constraint for synergy between the two events, leading to a proliferative advantage and suggests the utility of extended genotyping in myeloid malignancies.
Effect of Visit Frequency of Pharmacist-Led Diabetes Medication Management Program
Authors: Frederick Amy , Juan Joyce , Ivy Delaney , Maldonado Yolanda Munoz
Published: August 2020

Background:

Pharmacists have a positive effect on clinical outcomes in chronic disease state management, however, few studies have evaluated the effect that frequency of visits may have on diabetes biomarkers such as hemoglobin A1c and blood pressure readings.

Methods:

Under the medication management program (MMP), patients with diabetes were seen monthly by pharmacists until early 2015, when time between visits was increased to every 3 months. A retrospective chart review was conducted to evaluate the primary outcome of the percent change in hemoglobin A1c and blood pressure after the change in visit frequency.

Results:

In the 303 patients enrolled, no statistical difference existed between the pre and post average A1c (p-value = 0.10). The intermediate average A1c was statistically lower from the preintervention mean A1c (p-value = 0.001) but not from the postintervention mean A1c (p-value = 0.30). No statistical differences were seen between systolic blood pressure and diastolic blood pressure.

Conclusion:

Patients who have been seen by a clinical pharmacist more frequently (every month or every other month) for several years may be able to maintain their reduction in A1c with less-frequent visits (every 3 to 6 months).
Synergy between topology optimization and additive manufacturing in the automotive field
Authors: Mantovani S , Barbieri SG , Giacopini M , Croce A , Sola A , Bassoli E
Published: August 2020

This article purposes on developing and on re-interpreting the numerical results of a topology optimization for a structural component built via additive manufacturing. A critical appraisal of the optimization results is presented by modeling the feasible component with a holistic approach that merges structural and manufacturing requirements. The procedure is expected to provide a design guideline for similar applications of practical relevance, toward an increase of the right-first-time parts that is required to bring additive manufacturing to its full competitiveness. Topology optimization of a steering upright for a Formula SAE racing car was performed by targeting weight minimization while complying with severe structural constraints, like global and local stiffness performance. Cornering, bumping and braking vehicle conditions were considered. The optimization constraints were evaluated via finite element analysis on a reference component, where the loading conditions were retrieved from telemetry data. The reference part was manufactured by computer numerical control machining from a solid aluminum block. Spurred by the interpretation of the topology optimization predictions, a new upright geometry was designed and validated by calculating its stress field and the possible occurrence of Euler buckling. The new upright was 9% lighter than the reference component. The new geometry was analyzed according to Design for Additive Manufacturing principles to choose the orientation on the build platform and the supports’ location and geometry. The part was successfully manufactured and proved consistent with the application.
Avocado oil mixed with an antiwear additive as a potential lubricant – Measurement of antiwear and extreme pressure properties
Authors: Shafi Wani Khalid , Charoo M.S
Published: August 2020

The paper aims to study the antiwear (AW) and extreme pressure (EP) properties of avocado oil mixed with zinc dialkyl dithiophosphate (ZDDP) in concentrations of 1% to 3% by weight for lubrication purposes. The AW and EP tests are conducted as per ASTM-4172 and ASTM-2783 standards respectively. Further, the rheological behavior of avocado oil mixed with ZDDP is determined for varying shear rates of 50 – 2000 s−1. The maximum improvement in the wear properties for avocado oil is equal to 39.8% at 1 wt.%. The load wear index of pure avocado oil increases from 32.6 to 80.3 at 3 wt.% ZDDP whereas, the weld point increases to 252 kgf at 3 wt.% ZDDP. The improvement in the antiwear and extreme pressure properties are attributed to the protective film formation on the tribopairs as characterized by SEM and EDX analysis. Also, the addition of ZDDP increases the viscosity of the oil at all concentrations and maintains the Newtonian behavior of oil.
Machining performance of titanium alloy in short electric arc milling
Authors: Li XZ , Zhou JP , Wu TB , Xu Y , Wang KD
Published: August 2020

In order to solve the high-efficiency removal of difficult-to-cut materials such as titanium alloys, this paper conducts a in-depth research on the process characteristics of short electric arc milling machining (SEAM). The effects of processing conditions on material removal rate (MRR), tool wear ratio (TWR) and surface roughness (Ra) are studied. DeWesoft high-speed acquisition system, scanning electron microscope (SEM) and energy spectrometer (EDS) are used to characterize the machining performance of Ti-6Al-4V in SEAM. The results show that the surface of the machined Ti-6Al-4V has an obvious central depressions, surrounded by edge bumps and wrinkles caused by the melt. The effective number of short electric arc discharge is high, and the discharge rate can be maintained at a high level, increasing utilization rate of electric energy. The peak current of normal discharge reaches more than 900 A, which can generate a higher MRR. In addition, the surface morphology, re-solidified layer, and particle morphology of Ti-6Al-4V used for SEAM are also studied. These results lay a theoretical and technical foundation for the industrial application of SEAM.
Role of Physiotherapy in Hospice Care of Patients with Advanced Cancer: A Systematic Review
Authors: Vira Prina , Samuel Stephen Rajan , Amaravadi Sampath Kumar , Saxena PU Prakash , Rai PV Santosh , Kurian Jestina Rachel , Gururaj Rachita
Published: August 2020

Objective:

To review the role of physiotherapy and its effects in hospice care of patients with advanced cancer.

Methods:

A comprehensive literature search was performed in PubMed, Scopus, Web of Science, CINAHL and PEDro. The search strategy was devised, articles were screened, and 2 independent reviewers conducted data extraction. Eligible studies were methodologically assessed for quality rating using modified Downs and Black’s checklist. The extracted data was summarized according to site/stage of cancer, details of intervention, outcome measures and the results.

Result:

The total number of screened articles were 2102, out of which 9 were identified as suitable for the purposes of comprehensive review. The studies included exercise therapy, massage therapy, relaxation therapy, compression bandaging and use of TENS as the various physiotherapy interventions under consideration. Studies were generally of low to moderate quality. A broad range of outcomes were employed including physical symptoms like loss of function, pain, fatigue, edema, sleep disturbances and quality of life. The findings of the studies supported the benefits of the interventions.

Conclusion:

A structured exercise protocol, massage therapy, TENS and compression bandaging are useful in alleviating the symptoms experienced by patients with advanced cancer in hospice care. The reduced symptom burden has reflected as an improvement in their quality of life. However, there is a further need for high quality studies to strengthen the findings of this review.
“It Does Not Do to Dwell on Teaching Notes and Forget to Live”: Instructor Perspectives on Integrating and Adapting Existing Experiential Exercises in Large Classes
Authors: Agogué Marine , Robinson Melanie A.
Published: August 2020

The vast majority of articles describing new experiential exercises are presented from the perspective of the creator(s) of the activity. It is notable, however, that less research has focused on understanding the experiences of instructors who later adopt these exercises in their classrooms. We contribute to the literature on experiential learning in large classes by placing our focus squarely on the user—examining the perceptions, motivations, reflections, and experiences of instructors who integrate existing experiential exercises in large groups. Using a qualitative methodology, we interviewed 12 instructors of a large, multisection undergraduate course at a large Canadian university, in which a common experiential exercise is run across all sections. Two main themes emerged. The first captures the importance of making an exercise one’s own and reflects the variety of strategies that instructors use when preparing to adopt an existing exercise—including active strategies through which the instructors become codesigners of the activity itself. The second reflects different perceptions, ranging from enthusiasm to skepticism, with respect to the value of using experiential exercises. Both themes point to the importance of, as well as strategies designed to enhance, instructor perceptions of self-efficacy in relation to running existing experiential exercises in one’s courses.
Contemplative Pedagogy: Fostering Transformative Learning in a Critical Service Learning Course
Authors: Gardner Paula
Published: August 2020

Background: Research demonstrating the positive outcomes of service learning among university students is robust and some describe the impact as transformative. Purpose: To help me better understand how I can support transformative learning in my classroom, this study explored how an intergenerational critical service learning project fostered change among student participants. Methodology/Approach: Data consisted of reflection journals collected over 6 years from 228 students who participated in a course-based intergenerational service learning project and researcher field notes. Using a qualitative design and narrative methodology analysis took place over a 2-year period and consisted of a 3-stage process: deep reading, identifying stories, and re-storying to generate findings. Findings/Conclusions: Three mechanisms were found to foster transformation among students—writing as inquiry, embodied learning, and mindfulness. The two-pronged contemplative approach used in this course informs the way in which students experience the critical service learning project. Together, they provide a deep and transformative learning opportunity. Implications: Insights into course design and pedagogical approaches that support transformative learning.
Worth to Share? How Content Characteristics and Article Competitiveness Influence News Sharing on Social Network Sites
Authors: Karnowski Veronika , Leiner Dominik J. , Sophie Kümpel Anna , Leonhard Larissa
Published: August 2020

We investigated how sharing performance on Facebook and Twitter is influenced both by news articles’ content characteristics and the availability of additional news articles reporting on the same news topic. We conducted a multi-method study, integrating automated data collection and manual/automated content analyses of 1,764 German online news articles. Our findings show the influence of news factors and, more importantly, news outlets on sharing performance, while simultaneously highlighting differences between the logics of news sharing on Facebook and Twitter. We also find that the first article reporting on a news event is shared more often than subsequent articles.
Reconceptualizing Arab Media Research: Moving From Centrism Toward Inclusiveness and Balance
Authors: Kozman Claudia
Published: August 2020

This essay provides a brief overview of the dominant trends in Arab media research, paying particular attention to the most common methodologies they rely on. To understand the current state of Arab media scholarship, the article explores the various influences that have played a decisive role in determining the quality and quantity of research productivity. Factors such as the Arab countries’ historical roots, traditional societies, patterns in education, and current conflicts in the region are shown to have an impact on Arab scholars’ engagement with research. To aid the advancement of theory of Arab media research, this essay advocates for conducting collaborative research and proposes a hybrid approach that merges epistemologies in a culture-sensitive, empirical manner that is capable of making universal generalizations while staying true to the specificities of the region itself.
A Review of the Effects of the Violence Against Women Act on Law Enforcement
Authors: Jennings Wesley G. , Powers Ráchael A. , Perez Nicholas M.
Published: August 2020

One of the goals of the Violence Against Women Act (VAWA) was to improve law enforcement responses to sexual and domestic violence by providing funding to expand prevention, enhance investigations, and increase victim services. Since VAWA’s enactment, police responses to these crimes have evolved, including officer responses to victims and offenders, and various agency operations. This article highlights some noteworthy changes in law enforcement related to facilitating victim reporting, enhancing victim advocacy and services, crime reduction and investigative tools, supplementing personnel and training, and encouraging multiagency collaborations as a result of VAWA.
68-months progression-free survival with crizotinib treatment in a patient with metastatic ALK positive lung adenocarcinoma and sarcoidosis: A case report
Authors: Tanriverdi Ozgur , Tarimer Mehmet L , Pak Ceren D , Uylas Selcuk , Alkan Ali , Celik Ozgur Ilhan , Kilic Rabia M , Zeybek Arife
Published: August 2020

Introduction

Lung cancer still ranks first among the most common and most lethal cancers today. The most common subtype is non-small cell lung cancer, and in this group, adenocarcinoma has the worst prognosis. EGFR, ROS1 and ALK-EML4 gene fusion mutations are common in non-small cell lung cancer.

Case report

A 62-year-old non-smoker patient applied in February 2014 for purulent sputum and pain in the chest. Computed tomography revealed a 39x33 mm mass in the right hilum, multiple parenchymal nodules in the bilateral lung and mediastinal multiple enlarged lymph nodes. The patient was admitted to the lung adenocarcinoma as a result of a biopsy from the mass in the hilum, and sarcoidosis was diagnosed by mediastinal lymph node biopsy.

Management & outcome

After 4 cycles of carboplatin-pemetrexed for the first line treatment, progression was detected. The patient did not have EGFR and ROS1 mutations. The patient with positive ALK fusion mutation started crizotinib treatment in July 2014. The patient's last response assessment was in March 2020, with 68-progression-free disease with crizotinib. No toxicity was observed except for Grade 1 weakness. No dose changes were made. The patient is still being followed up without brain metastasis under the treatment of crizotinib.

Discussion

In this article, we wanted to share our experience of crizotinib in a 68-months progression-free survival in a 62-years old non-smoking female patient with metastatic lung adenocarcinoma who is also diagnosed with sarcoidosis.
Intrastromal corneal ring segment implantation in paracentral keratoconus with perpendicular topographic astigmatism and comatic axis
Authors: Fernández-Vega-Cueto Luis , Lisa Carlos , Alfonso-Bartolozzi Belén , Madrid-Costa David , Alfonso José F
Published: August 2020

Purpose:

To evaluate the outcomes of implanting intrastromal corneal ring segment (ICRS) using two different strategies in a specific paracentral keratoconus phenotype.

Methods:

Eighty-nine eyes with paracentral keratoconus with perpendicular topographic astigmatism and comatic axes were evaluated before and after implanting a 150° arc-length ICRS. Patients were divided into two groups according to the axis where the ICRS was implanted: Group I: comatic axis and Group II: flat topographic axis. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refractive errors, and root mean square (RMS) for coma-like aberration were recorded. The postoperative follow-up was 1 year.

Results:

Mean UDVA (logMAR) changed from 0.49 ± 0.37 preoperatively to 0.30 ± 0.32 6 months afterwards ( p < 0.001) in the group I and from 0.53 ± 0.34 to 0.37 ± 0.35 ( p < 0.001), in the group II. Mean CDVA in group I changed from 0.11 ± 0.18 preoperatively to 0.06 ± 0.14 6 months after surgery ( p < 0.001). In group II the improvement did not reach statistical significance (from 0.09 ± 0.10 to 0.07 ± 0.09; p = 0.06). No eyes lost lines of CDVA in group I. Eight eyes (15.7%) lost lines of CDVA in group II. The spherical equivalent decreased after surgery in both groups ( p < 0.001). The RMS for corneal coma-like aberration only decreased in the group I ( p < 0.001).

Conclusion:

Both strategies provided safe and effective visual and refractive outcomes in the specific keratoconus phenotype analyzed. The orthopedic strategy provided better visual outcomes than the refractive one.
Functional electrical stimulation for foot drop in people with multiple sclerosis: The relevance and importance of addressing quality of movement
Authors: Smith Angela Davies , Prokopiusova Terezie , Jones Rosemary , Burge Tania , Rasova Kamila
Published: August 2020

Impaired mobility is common in people with multiple sclerosis (MS). Changes in gait have different causes and require individualised gait rehabilitation. A common and often early cause of mobility impairment is footdrop, inability to lift the foot during the swing phase of gait, with increased risk of falls, effortful walking and fatigue. Using literature review, we have characterised published data on footdrop treatment in MS, specifically functional electrical stimulation (FES) to better understand the reported outcomes relevant to the user. We discuss the strengths and weaknesses of FES and how far it meets the needs of people with footdrop. Physiotherapy combined with FES may further enhance the benefits of FES. MS studies emphasise the value of maintaining activity levels in early MS but discussion on how to achieve this is lacking. We emphasise the value of qualitative measures to broaden our understanding and improve treatment and adherence and identify areas for further research. Supplementary video material illustrates key features of MS gait and its correction using FES and physiotherapy.
Associations of childhood trauma experiences with religious and spiritual struggles
Authors: Janů Anna , Malinakova Klara , Kosarkova Alice , Tavel Peter
Published: August 2020

Childhood trauma is associated with many interpersonal and psychosocial problems in adulthood. The aim of this study was to explore the associations with a spiritual area of personality, namely religious and spiritual struggles (R/S struggles). A nationally representative sample of 1,000 Czech respondents aged 15 years and older participated in the survey. All types of CT were associated with an increased level of all six types of R/S struggles, with the highest values for demonic struggles. Thus, the findings of this study might be important for clinical practice and pastoral care as well as a further research.
Transnational social work: Challenging and crossing borders and boundaries
Authors: Schrooten Mieke
Published: August 2020

Interest in transnationality and borders has expanded considerably within several academic disciplines over the last decades. This paper explores the way this transnational perspective has been developed within social work. It then identifies a number of gaps in current transnational social work research and proposes four avenues for additional inquiry that allow for an unbounding of how social work is theorised and the development of a perspective that recognises social work’s role beyond a bounded national state.

Findings

Borders and cross-border processes and structures pose essential challenges to social work research and practice. State borders may be opening to certain cyber, social and economic functions, but are at the same time (re-)closing to other security and political functions. Moreover, more metaphorical and symbolic boundaries are also strengthening. A transnational turn in the educational, theoretical and practical field of social work requires a move away from the conventional local and sedentary conceptualisation of society and social life that is still omnipresent today, in order to develop a social work that recognises and explores, as well as challenges and crosses borders and boundaries.

Applications

Despite the increase of transnational lifestyles, social problems and social work practices, the body of knowledge in this domain is as yet rather limited and fragmented. The applications of this article concern a theoretical contribution to this body of knowledge, which can also be used in curricula for social work education. Moreover, it contributes to a move away from the ‘methodological nationalism’ at work in social work.
After Eat, Pray, Love: Tourism, Orientalism, and cartographies of salvation
Authors: Putcha Rumya Sree
Published: August 2020

This article examines certain kinds of travel and tourism as extensions of colonial and examples of neocolonial forms of Orientalist engagement between the global North and global South. Focusing on areas that border the Indian Ocean, and the South Asian context in particular, I interrogate the gendered, racial, and geopolitical attachments that have historically drawn and continue to draw travelers to the region for tourism. I refer to these attachments as cartographies of salvation. In connecting the history and representations of travel to the area to the forms of leisure and spiritual tourism popularized by the 2006 memoir, Eat, Pray, Love, I argue that the Indian Ocean region remains for many a paternalistic endeavor or an exotic playground, where one can project a sense of purpose or indulge in an escapist fantasy. This article combines critical tourism studies, feminist ethnography and theory, and critical race studies.
‘I’m a person who loves beautiful things’: Potassa de Lafayette as model and muse
Authors: Carmack Kara
Published: August 2020

In January 1977, Potassa de Lafayette visited Andy Warhol’s studio wearing a black velvet and taffeta evening gown. The Dominican model sat for sketches by visiting artist Jamie Wyeth and photographs taken by Warhol that together reveal the sequence in which Potassa raised her skirt and lowered her stockings to expose her penis. This contribution explores Potassa’s strategies of self-presentation amid the politics at play in the studio that day. The author reads Potassa as a self-possessed figure fully in control of her image because hers is an identity not predicated on a gendered or sexed body, but on a visual sensibility – as one who ‘loves beautiful things’. As an aesthete and as one of the first openly transgender models of color, Potassa, the author argues, negotiated difference through beauty and glamor in Warhol’s studio and across New York’s high art and fashion scenes.
Hospital care for opioid use disorder in pregnancy: Challenges and opportunities identified from a Minnesota survey
Authors: Dopp Alana , Zabel Thornton Morgan , Kozhimannil Katy , Jones Cresta W , Greenfield Brenna
Published: August 2020

Objectives:

The prevalence of opioid use disorder continues to rise in the United States, with a simultaneous increase in the diagnosis of both opioid use disorder during pregnancy and neonatal opioid withdrawal syndrome. Despite these increases in pregnancy-related care, little is known about hospital policy and policy implementation related to opioid use disorder in pregnancy. In addition, it is unknown whether policies might differ in rural or urban hospitals. To better examine these issues, Minnesota hospitals were surveyed regarding the existence and implementation of policies related to opioid use disorder in pregnancy and whether any policy implementation challenges had been identified.

Methods:

From August to December 2017, the research team contacted all Minnesota hospitals that offered obstetric services ( n = 82) to survey challenges to implementing policies for opioid use disorder during pregnancy, among other questions. Fifty-nine hospitals had respondents (primarily obstetric department supervisors) who provided information about policy implementation challenges for a 72% response rate. Qualitative responses were analyzed using qualitative description and according to hospital location: metropolitan (urban), micropolitan (rural), or non-core (rural).

Results:

Ninety-one percent of respondents said that they had pregnancies affected by opioid use disorder at their hospital within the last year. Four major challenges to policy implementation were identified in qualitative responses: (1) provider consensus, (2) patient response to policy, (3) lack of resources, and (4) low frequency of occurrence. All four challenges were more frequently identified by respondents at rural hospitals compared to urban hospitals.

Conclusion:

This study identified challenges in standardizing hospital care for pregnancies affected by opioid use disorder, and these challenges were identified more frequently in rural locations. These non-urban hospitals may require increased state and federal support and funding.