bluuebunny/crossref_metadata_2025 huggingface dataset:
Fortaleciendo Competencias Digitales: Recomendación de Estrategias Prácticas para Maestros que Usan Neo LMS En Latinoamérica
Authors:   CYPHER LEARING. Estado de México, Ixtapaluca. México, Herrera López Patricia
Published: August 2024

En la era digital actual, el dominio de las competencias digitales por parte de los docentes es fundamental para potenciar el aprendizaje de los estudiantes. En este estudio se aborda la necesidad a través del análisis de la implementación de estrategias pedagógicas con la plataforma NEO LMS en América Latina. En dicha investigación se evaluó cómo el uso efectivo de NEO LMS puede mejorar las habilidades digitales de los docentes y, a su vez, enriquecer la experiencia de aprendizaje de los estudiantes en modalidades en línea, virtual y presencial. A través de un enfoque cualitativo y un diseño no experimental transversal, el estudio recogió datos de 549 docentes en eventos educativos en países como México, Perú y Colombia. Las estrategias examinadas incluyeron gamificación, aprendizaje adaptativo, el aula invertida, aprendizaje basado en competencias y microlearning, impartidas en masterclasses diseñadas para ofrecer una capacitación práctica y aplicable. Los hallazgos revelan que la mayoría de los participantes valoraron altamente la relevancia y aplicabilidad de las estrategias pedagógicas presentadas, reportando un impacto positivo en la práctica docente y el aprendizaje de los estudiantes. Específicamente, se observó que el aprendizaje sobre estas estrategias y su implementación adecuada contribuyó a un uso más efectivo de las herramientas de NEO LMS, lo que a su vez favoreció una experiencia educativa de mayor calidad. A pesar de los resultados positivos, el estudio identifica la necesidad de una capacitación y evaluación continuas para los docentes. La adopción y efectividad de nuevas herramientas y enfoques pedagógicos requieren de un compromiso constante y un esfuerzo sostenido para garantizar resultados óptimos a largo plazo. La investigación subraya la importancia de estrategias pedagógicas bien diseñadas y la capacitación docente como elementos clave para mejorar la enseñanza y el aprendizaje en entornos digitales, enfatizando la relevancia de estas prácticas en la mejora continua de la educación virtual. Este estudio contribuye a la comprensión de cómo la capacitación enfocada y la implementación de estrategias pedagógicas específicas pueden mejorar significativamente las competencias digitales de los docentes en América Latina, ofreciendo insights valiosos para futuras investigaciones y prácticas educativas en la región.
Dos páginas resguardadas en el estudio de Rubén Salazar Mallén
Authors:   Universidad Autónoma de Chiapas, Tuxtla Gutiérrez, Chiapas, México, Martínez Torres José , Durán Ruiz Antonio ,   Universidad Autónoma de Chiapas, Tuxtla Gutiérrez, Chiapas, México
Published: August 2024

La siguiente colaboración presenta dos breves fragmentos que se resguardaban en el estudio de Rubén Salazar Mallén, uno es un volante que se repartía en la calle con el título de LA MASCULINIDAD. / MÁS VALE PREVENIR QUE LAMENTAR. / MANIFIESTO DEL 31 DE OCTUBRE DE 1934. Las primeras décadas del siglo XX dan muestra de una ponderación de valores ––éticos, morales–– exacerbados por la Revolución mexicana y que hoy parecen decididamente obsoletos, lo mismo que la breve escena que por autocensura eliminó el propio autor de la novela La iniciación en sus dos primeras ediciones.
THE RELEVANCE OF THE TEACHING OF PSYCHOLOGICAL AND PEDAGOGICAL DISCIPLINES IN THE INSTITUTIONS OF HIGHER EDUCATION
Authors:   Ivan Ziaziun Institute of Pedagogical Education and Adult Education of the NAPS of Ukraine, PETRENKO Larysa
Published: August 2024

Introduction. Pedagogy and psychology as human sciences, mastery of his or her formation and development as an individual, a family man, a profes-sional and a citizen occupy a prominent place among socio-humanitarian disciplines. Psychological and peda-gogical knowledge, skills and a set of life competencies are relevant today for the modern family and the upbring-ing of children within it, the personal and professional development of each person throughout life, the construc-tion of a civil society and the influence of which on the formation of the value system of modern youth is uncondi-tional. Purpose. To justify the relevance of teaching psycho-logical and pedagogical disciplines in the institutions of higher education. Methods. Analysis of normative and legal documents in the field of education, strategies of human development and higher education, vocabulary, scientific-pedagogical and scientific-psychological literature, experience of teach-ing psychological and pedagogical disciplines in the insti-tutions of higher education. Results. Factors influencing the formation of a person were singled out. The role of pedagogy and psychology in the formation of the personality of future specialists of various specialties was defined, attention was focused on the formation of their ability to learn throughout life and psychological and pedagogical competences, which are in demand in the market of educational services for the performance of various roles: teacher of a higher educa-tion institution, business trainer, mentor , tutor, coach, facilitator. Scientific novelty of the results. The actualities of teaching psychological and pedagogical disciplines in the institutions of higher education, the solution of which will contribute to the spiritual and cultural development of the individual, the formation of a civic position and readiness for taking the responsible decisions were highlighted and positioned. Conclusions and specific suggestions of the author. The actualities of teaching socio-humanitarian disciplines are positioned, the improvement of teaching of which will contribute to the formation of an individual, a profession-al, a family member and a citizen, which will ensure the further development of civil society during the post-war period. The further study of the problem of improving the system of teaching psychological and pedagogical disci-plines in the institutions of higher education, was pro-posed.
Lightweight Concretes on Hollow and Porous Aggregates
Authors: INOZEMTCEV A.S. , KOROLEV E.V.
Published: August 2024

One of the directions of development of concrete science is the combination of positive qualities of heavy and lightweight concretes. The problem of optimizing the structural properties of heavy concrete and the thermal properties of lightweight concrete is solved in a large number of scientific papers. In Russia, the most popular structural lightweight concretes are those based on expanded clay aggregate. Recently, there has been experience in reconstructing bridges made of lightweight concrete on hollow microspheres. Over the past 10 years, the possibilities for producing lightweight concrete with increased strength have improved significantly. The paper presents models demonstrating the features of the formation of the structure of lightweight concrete on hollow and porous aggregates. The advantages and limitations are described for each of the aggregates for obtaining lightweight concrete with a given average density and strength. The described models show that it is advisable to use porous filler to obtain high-strength lightweight concrete with an average density of more than 1600 kg/m3, and hollow filler at ρlb<1600 kg/m3. The thickness of the filler shell becomes the determining factor in achieving the required specific strength of lightweight concrete
Analysis of the Properties of Asphalt Granulate as Raw Materials for Obtaining Organomineral Composites
Authors: STEPANENKO M.A. , MARKOVA I.Yu. , LUKYANENKO N.O. , STROKOVA V.V. , BOATSMAIN L.N.
Published: August 2024

Increasing and maintaining the pace of construction and repair work associated with the development of the highway network, as well as improving the quality of communication between subjects and transport hubs, requires a huge amount of resource consumption, and, accordingly, creates a significant burden on the country’s economy. One of the rational solutions in the road construction industry, which allows reducing the cost of raw materials, is the reuse of materials from existing highway structures. The most common options in both domestic and foreign practice is the use of regeneration technologies for the quantitatively predominant asphalt concrete road surfaces. However, when reusing asphalt concrete, in order to establish the recipe and technological features of the designed composites, it is necessary to evaluate the properties of asphalt concrete after wear and the possible mutual influence of the components used in its composition on the formation of the final properties of new composites. In this regard, the presented work is devoted to the analysis of a complex of properties of asphalt granulate samples and the establishment of patterns of their changes depending on the composition and service life. Based on the studies conducted, it was established that the composition of the mineral part of asphalt granulate and the amount of organic binder are within the standardized ranges. Noteworthy is the decrease in the physical and mechanical characteristics of the mineral part with an increase in the service life of asphalt concrete for more than five years, as well as a change in the composition of the organic binder, leading to a decrease in its relaxing ability. Depending on the composition and properties of asphalt granulate, options for its further use are proposed.
Estudio controlado sobre la adherencia a la dieta mediterránea en adolescentes con primer episodio psicótico
Authors: Padilla M. , Puig O. , De la Serna E. , Labad J. , Camprodon-Boadas P. , Baeza I.
Published: August 2024

Introducción: la Adherencia a la Dieta Mediterránea (ADM) se asocia a la prevención de riesgos de enfermedades cardiovasculares, inflamatorias y neurodegenerativas. Además, algunos estudios sugieren una reducción en los problemas de salud mental. El estatus socioeconómico y la sobrecarga del cuidador podrían influir en la ADM. Objetivo: evaluar ADM, estatus socioeconómico y sobrecarga del cuidador en adolescentes con primer episodio psicótico (PEP) y compararla con controles. Metodología: estudio transversal en el que se incluyeron 27 pacientes con un PEP y 38 controles. Todos los participantes completaron el cuestionario KIDMED, que mide ADM, el test de Hollingshead que evalúa el estatus socioeconómico y la escala Caregiver Burden Inventory que valora el riesgo de sobrecarga del cuidador. Resultados: no se observaron diferencias significativas en las medias del cuestionario KIDMED entre pacientes (6,2±2,7) y controles (6,78±2,74). La ADM no se correlacionó con el riesgo de sobrecarga del cuidador (R=-0,165 p=0,442). Existió una correlación negativa con el estatus socioeconómico en el grupo de pacientes (R= -0,390 p=0,04). En los ítems de KIDMED, los pacientes mostraron diferencias significativas en el ítem 6, uso de comida fast food (X2=0,006 p=0,010) y el ítem 12, no desayuna (x2=0,017, p=0,027) presentando los pacientes un patrón desfavorable de alimentación. Conclusiones: no se han observado diferencias en la ADM entre adolescentes con un primer episodio psicótico y controles, aunque existen aspectos concretos en los que los pacientes se alejan de la dieta mediterránea y podrían tener un impacto en su salud.
Impacto de la Covid en urgencias de psiquiatría infantil en el Hospital Clínico de Zaragoza
Authors: Goñi Navarro A. , Ruiz Lázaro P. M. , Pírez Mora G. J. , Calvo Sárnago A. I. , Yárnoz Goñi N.
Published: August 2024

Introducción: en marzo de 2020, la Organización Mundial de la Salud declaraba que la Covid-19 se elevaba a categoría de pandemia mundial, causando un elevado impacto bio-psico-social en la población menor de edad. Algunos posibles factores que han podido influir fueron el cierre de escuelas, el aislamiento social y la interrupción de rutinas diarias, entre otros. Material y métodos: se realizó un estudio descriptivo observacional retrospectivo sobre el número y tipo de urgencias atendidas mediante el estudio de características demográficas como sexo, edad, además de, motivo de consulta y destino tras la valoración en el Servicio de Urgencias. Resultados: los datos muestran un aumento del 20% de asistencia en relación con datos previos recogidos en la misma franja de meses correspondientes al año 2017. La edad media de consulta fue de 14,9 años. En cuanto al sexo, existe un predominio femenino con un 65% de las consultas realizadas. El diagnóstico más frecuente fue el de trastorno de ansiedad, seguido del de trastorno del estado de ánimo. Conclusiones: los niños y adolescentes suponen una población vulnerable en términos de salud mental. Destaca un incremento del 20% en la demanda de asistencia en urgencias psiquiátricas de infanto-juvenil en los meses posteriores al confinamiento, respecto a años previos. Es por ello que creemos necesario el trabajo de equipos interdisciplinares, haciendo hincapié en la detección precoz, dando respuesta a las necesidades de los menores y sus familias.
Mucoadhesive Microspheres: An Insight Review
Authors: Ganju Eisha , Prajapati Shubham , Gupta Bhaskar Kumar
Published: August 2024

Mucoadhesive microspheres are an advanced drug delivery system designed to enhance the bioavailability and therapeutic efficacy of drugs by adhering to mucosal surfaces. These microspheres offer prolonged residence time, controlled drug release, and targeted delivery to specific mucosal sites, making them ideal for oral, nasal, ocular, and vaginal applications. This review aims to provide a comprehensive overview of the formulation strategies, characterization techniques, and therapeutic applications of mucoadhesive microspheres. A thorough literature search was conducted using databases such as PubMed, Scopus, and Web of Science. Articles focusing on the development, evaluation, and clinical applications of mucoadhesive microspheres were included. The review covers the selection of polymers, methods of preparation, and characterization techniques for assessing mucoadhesive properties, particle size, drug encapsulation efficiency, and in vitro/in vivo drug release profiles. The review identified various natural and synthetic polymers, including chitosan, alginate, and carbopol, as effective mucoadhesive agents. Preparation techniques such as emulsification, spray drying, and solvent evaporation were discussed, highlighting their impact on the physical and chemical properties of the microspheres. Characterization methods such as scanning electron microscopy (SEM), differential scanning calorimetry (DSC), and mucoadhesion testing were examined. Studies demonstrated that mucoadhesive microspheres significantly enhance drug absorption and bioavailability by adhering to mucosal tissues and providing controlled drug release. Therapeutic applications span across multiple fields, including gastroenterology, pulmonology, and ophthalmology, with promising results in improving patient compliance and treatment outcomes. Mucoadhesive microspheres represent a promising drug delivery system with the potential to revolutionize the administration of pharmaceuticals. Their ability to adhere to mucosal surfaces, provide controlled and sustained drug release, and enhance bioavailability makes them suitable for various therapeutic applications. Future research should focus on optimizing formulation parameters, exploring novel mucoadhesive polymers, and conducting clinical trials to establish their efficacy and safety. The advancements in mucoadhesive microspheres hold significant promise for improving drug delivery and therapeutic outcomes across different medical fields.
Формирование покрытий SiO₂@NPs (NPs = Ag, Au, CdS) из декановых органогелей на предметных стеклах в присутствии AOT
Authors: Подлипская Т. Ю. , Шапаренко Н. О. , Булавченко A. И.
Published: August 2024

В работе продемонстрирована возможность выделения гелей из органозолей диоксида кремния высокоскоростным центрифугированием. В качестве окрашивающих добавок использовали органозоли наночастиц (NPs) Ag, Au и CdS, синтезированные в обратных эмульсиях АОТ. Пористые шероховатые покрытия из гелей формировали методом Doctor Blade с последующей сушкой и термолизом при 500°С. Полученные покрытия перспективны для медико-биологического, фотовольтаического и фотокаталитического применений.
Исследование каталитических свойств и коррозионной стойкости никелевой пены на медной подложке в процессе низкотемпературного окисления этанола в сильнощелочной среде
Authors: Таранцева К. Р. , Таранцев К. В. , Полянскова Е. A.
Published: August 2024

Методами циклической вольтамперометрии и электрохимического импеданса исследована каталитическая активность никелевой пены на медной подложке в процессе окисления этанола в сильнощелочных средах, предложенных для безмембранных топливных элементов. Исследования подтвердили, высокую активность катализатора NiFoam/Cu в процессах окисления этанола в данных средах. Выявлено, что окисление этанола на никелевой пене проходит согласно механизму окисления этанола в сильнощелочных средах. Этанол начинает окисляться при потенциалах с –350 мВ, на Ni(OH)2, далее продолжает окисляться, после образования оксигидроксида Ni(OOH), когда степень окисления никеля изменяется от +2 до +3. Исследования показали высокую химическую стойкость катализатора, его набухания и отслаивания от подложки не наблюдалось. Показано, что данный катализатор может быть взят за основу для последующего нанесения на него слоев оксидов кобальта, железа и других компонентов с целью улучшения его каталитических характеристик в процессах низкотемпературного окисления этанола.
Synthesis and Transformations of Hydrazine-Substituted Pyrano[3″,4″:5′,6′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine
Authors: Dabaeva V. V. , Paronikyan E. G. , Barkhudaryants I. M. , Dashyan Sh. Sh. , Baghdasaryana M. R.
Published: August 2024

A method was developed for the synthesis of 11-(2-furyl)-4-hydrazino-8,8-dimethyl-7,10-dihydro-8H-pyrano[3″,4″:5′,6′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine on the basis of which new heterocyclic systems were synthesized. The conditions for the azido/tetrazole transformation of the resulting condensed tetrazolo[1,5-c]pyrimidine were studied. Isomeric triazolo[4,3-c]- and -[1,5-c]pyrimidines were synthesized and the conditions for the transformation of the first isomer into the second in accordance with the Dimroth rearrangement were established.
Alkylation of Adenyne with (Halomethyl)trimethylsilanes
Authors: Lazareva N. F. , Albanov A. I. , Gostevsky B. A. , Lazarev I. M.
Published: August 2024

The reaction of adenine with (halomethyl)trimethylsilanes HlgCH₂SiMe3 (Hlg = Cl, I) in the presence of a strong base and under neutral conditions was studied. The structure of the reaction products was proven by NMR spectroscopy. For the first time, NMR spectroscopy methods have proven that the interaction of adenine with 1,8-diazabicycloundecene leads to the formation of an adenine anion.
Properties of Hydrolyzed Polyalumotris(acetylacetonato)ethylsiloxane
Authors: Shapkin N. P. , Pervakov K. A. , Fedorets A. N. , Lembikov A. O. , Dran’kov A. N. , Savchenko V. G.
Published: August 2024

The work is devoted to the study of the structural and sorption properties of metal exchangers obtained under conditions of extraction by hydrochloric acid (1:2) of the product of interaction of tris(3-chlorosulfenyl)-2,4-aluminum pentanedionate with vinyl trichlorosilane. The reaction was considered using two organic solvents – chloroform and toluene. A comparison of diffractometric parameters, elemental analysis, NMR spectra, thermogravimetric curves, as well as surfaces (SEM) and internal structure of isolated substances was presented. The capacity of the products with respect to Fe³⁺ is on the order of 7.1 mg·eq/g.
Synthesis of Copper-Nickel Bimetallic Nanoparticles by Caprylate Reduction in Benzyl Alcohol
Authors: Titkov A. I. , Gerasimov E. Yu. , Vorobyov A. M. , Malbakhova I. A. , Borisenko T. A. , Logutenkо O. A.
Published: August 2024

Based on the process of joint reduction of copper and nickel caprylates in benzyl alcohol at 185°C, a simple method for the synthesis of bimetallic copper and nickel nanoparticles was developed. The prepared bimetallic nanoparticles may be of interest for creating new compositions of electrically conductive inks and pastes for 2D and 3D printing. The resulting nanoparticles were characterized by X-ray phase analysis, scanning and transmission electron microscopy in combination with energy-dispersive X-ray spectroscopy. The prepared copper and nickel nanoparticles are single- or two-phase bimetallic solid solutions of various compositions. The effect of the phase composition of bimetallic powders on their resistance to oxidation was studied. It was shown that an increase in the nickel content in the composition leads to a decrease in the degree of nanoparticles oxidation. The proposed method is one-step, does not require the use of additional stabilizers and reducing agents, the synthesis is carried out in one-pot and is easily scalable. The method can also be used to obtain other bi- and polymetallic nanoparticles.
RELATIONSHIP OF CYTOTOXIC AND ANTIMICROBIAL EFFECTS OF TRIPHENYLPHOSPHONIUM CONJUGATES WITH VARIOUS QUINONE DERIVATIVES
Authors: Nazarov P. A , Zinovkina L. A , Brezgunova A. A , Lyamzaev K. G , Golovin A. V , Karakozova M. V , Kotova E. A , Plotnikov E. Yu , Zinovkin R. A , Skulachev M. V , Antonenko Yu. N
Published: August 2024

Quinone derivatives of triphenylphosphonium have proven themselves to be effective geroprotectors and antioxidants that prevent the oxidation of cell components with the participation of active free radicals – peroxide (RO2•), alkoxy (RO•), alkyl (R•), as well as reactive oxygen species (superoxide anion, singlet oxygen). The most studied representatives are derivatives of plastoquinone (SkQ1) and ubiquinone (MitoQ), which in addition to antioxidant properties also had a strong antibacterial effect. Other quinone derivatives based on decyltriphenylphosphonium (SkQ3, SkQT, and SkQThy) have been less studied and their antibacterial activity remains undiscovered. In this work, we investigated the antibacterial properties of quinone derivatives based on decyltriphenylphosphonium. We have shown that, as in the case of SkQ1, they are effective against various gram-positive bacteria, while they are not so effective against gram-negative bacteria. This is associated with their recognition by the main multidrug resistance pump of gram-negative bacteria AcrAB-TolC. Moreover, in the case of SkQ1 itself, there is a dependence of its action on the number of bacterial cells and the molar amount of the antibiotic itself, which distinguishes it from conventional antibiotics. At the same time, the cytotoxic effect on mammalian cells is observed in higher concentrations, which suggests the presence of a protective effect caused by the separation of the process of energy generation and transport on the cell membrane. Another possible explanation could be the different composition of multidrug-resistant (MDR) pumps. The difference in cytotoxic effects on mammalian cells may be due to different expression profiles of MDR pumps in different cell types.
MITOCENTRICITY
Authors: Zorov D. B , Abramicheva P. A , Andrianova N. V , Babenko V. A , Zorova L. D , Zorov S. D , Pevzner I. B , Popkov V. A , Semenovich D. S , Yakupova E. I , Silachev D. N , Plotnikov E. Y , Sukhikh G. T
Published: August 2024

Worldwide, interest in mitochondria is constantly growing, as evidenced by scientific statistics, and studies of the functioning of these organelles are becoming more prevalent than studies of other cellular structures. In this analytical review, mitochondria are conditionally placed in a certain cellular center, which is responsible for both energy production and other non-energetic functions, without which the existence of not only the eukaryotic cell itself, but also the entire organism is impossible. Taking into account the high multifunctionality of mitochondria, such a fundamentally new scheme of cell functioning organization, including mitochondrial management of processes that determine cell survival and death, may be justified. Considering that this issue is dedicated to the memory of V. P. Skulachev, who can be called mitocentric, due to the history of his scientific activity almost entirely aimed at studying mitochondria, this work examines those aspects of mitochondrial functioning that were directly or indirectly the focus of attention of this outstanding scientist. We list all possible known mitochondrial functions, including membrane potential generation, synthesis of Fe–S clusters, steroid hormones, heme, fatty acids, and CO2. Special attention is paid to the participation of mitochondria in the formation and transport of water, as a powerful biochemical cellular and mitochondrial regulator. The history of research on reactive oxygen species that generate mitochondria is subject to significant analysis. In the section “Mitochondria in the Center of Death”, special emphasis is placed on the analysis of what role and how mitochondria can play and determine the program of death of an organism (phenoptosis) and the contribution made to these studies by V. P. Skulachev.
FRAMEWORK ELEMENTS OR FREE INTERCELLULAR GEL-LIKE MATRIX AS A NECESSARY CONDITION FOR BUILDING OF ORGAN STRUCTURES DURING REGENERATION
Authors: Manskikh V. N
Published: August 2024

Over the past decades, an unimaginably large number of attempts have been made to restore the structure of mammalian organs after damage by introducing stem cells into them. However, this procedure does not lead to a full recovery. At the same time, it is known that complete regeneration (restitution without fibrosis) is possible in organs with proliferating parenchymal cells. An analysis of such models allows us to conclude that the most important condition for the repair of the histological structures of an organ (in the presence of a stem cells) is the preservation of collagen frame structures in it, which serve as “guide rails” for proliferating and differentiating cells. An alternative condition for the complete reconstruction of organ structures is the presence of a free “morphogenetic space” consisting of a gel-like matrix of the embryonic-type connective tissue, which takes place in embryonal development of organs in mammalians or during complete regeneration in amphibians. Approaches aimed at preserving scaffold structures or creating a “morphogenetic space” could radically improve the results of organ regeneration using both local and exogenous stem cells.
EVOLUTION OF LONGEVITY IN TETRAPODA: SAFETY IS MORE IMPORTANT THAN METABOLISM LEVEL
Authors: Shilovsky G. A , Putyatina T. S , Markov A. V
Published: August 2024

Various environmental morphological and behavioral factors may be decisive in the longevity of representatives of various taxa. Long-lived species develop systems aimed at increasing the body’s stability and defense, and ultimately increasing life expectancy. In addition, long-living species are characterized by different levels of manifestation of factors favorable to longevity (gerontological success): body size, slow metabolism, level of activity of the body’s repair systems and antioxidant defense systems, resistance to toxic substances and tumor formation, and the presence of neotenic characteristics. Continuing the work on mammals, in this work we studied the characteristics that distinguish long-lived ectotherms (crocodiles and turtles) and compared them with those of other representatives of ectotherms (squamates and amphibians) and endotherms (birds and mammals). The article also discusses mathematical indicators used to assess the predisposition to longevity in different species. These indicators include both standard ones (mortality rate, maximum lifespan, coefficient of variation of lifespan) and derivatives from them. evolutionary patterns of aging are further explained by protective phenotypes and life history strategies. The work assessed the relationship between lifespan and various studied factors, including body size and temperature, encephalization, protection of occupied econiches, the presence of protective structures (for example, shell and osteoderms), environmental temperature, etc.), and their influence on the distribution of lifespan as a statistical quantities. The hypothesis about the level of metabolism and temperature as the most determining factors of longevity was not confirmed. It turned out that animals protected by shells (turtles with their exceptional longevity) live longer than species that have poison or lack protective devices. The improvement of methods of defense against external threats in long-lived ectotherms is consistent with the characteristics of long-lived endotherms (for example, naked mole rats that live in tunnels underground, or bats and birds, whose ability to fly is also one of the best methods of defense).
EXPLORING PATTERNS OF HUMAN MORTALITY AND AGING: A RELIABILITY THEORY VIEWPOINT
Authors: Gavrilov L. A , Gavrilova N. S
Published: August 2024

The most important manifestation of aging is an increased risk of death with advancing age, a mortality pattern characterized by empirical regularities known as mortality laws. We highlight three significant ones: the Gompertz law, compensation effect of mortality (CEM), and late-life mortality deceleration and describe new developments in this area. It is predicted that CEM should result in declining relative variability of mortality at older ages. The quiescent phase hypothesis of negligible actuarial aging at younger adult ages is tested and refuted by analyzing mortality of the most recent birth cohorts. To comprehend the aging mechanisms, it is crucial to explain the observed empirical mortality patterns. As an illustrative example of data-directed modeling and the insights it provides, we briefly describe two different reliability models applied to human mortality patterns. The explanation of aging using a reliability theory approach aligns with evolutionary theories of aging, including idea of chronic phenoptosis. This alignment stems from their focus on elucidating the process of organismal deterioration itself, rather than addressing the reasons why organisms are not designed for perpetual existence. This article is a part of a special issue of the journal that commemorates the legacy of the eminent Russian scientist Vladimir Petrovich Skulachev (1935-2023) and his bold ideas about evolution of biological aging and phenoptosis.
ПРОБЛЕМИ ТА ПРІОРИТЕТНІ НАПРЯМКИ РОЗВИТКУ ЕКОНОМІЧНИХ ВІДНОСИН МІЖ УКРАЇНОЮ ТА КНР
Authors: БОНДАРЕНКО Валерій , ЛІ Цзехао
Published: August 2024

Trade cooperation between Ukraine and China is based on positive historical experience. The institutional, including legislative, regulatory, and legal framework for Ukraine-China trade relations covers political, defense, trade and economic, cultural, educational, scientific and technical, tourism, migration, investment, and transport and logistics components. Trade relations have been the most developed so far.
During 2001-2020, there was a stable trend towards an increase in foreign trade turnover. At the same time, for Ukraine, the commodity structure of trade with China is characterized by negative indicators, both in quantitative (negative trade balance in goods) and qualitative (predominance of raw material exports, low level of commodity diversification, dominance of high-tech goods in imports) dimensions.
The development of Ukrainian-Chinese cooperation is becoming more multidirectional. Both sides approach the establishment of more productive interaction primarily from the standpoint of ensuring national interests. The PRC takes into account Ukraine's real capabilities and prospects in the agricultural sector and developments in technical fields, such as aircraft construction, for example. For Ukraine, China is currently a market for promoting its products and a source of investment in the economy. The attractiveness of this direction of Ukraine's foreign policy is determined by many factors, not the least of which is the ever-growing political and economic weight of China in the world.
The study has identified the following factors that contribute to the growing interest of Chinese investors in Ukrainian markets: openness and economic freedom, increased market potential, successful investments in the past; signing of the Association Agreement with the EU and further strengthening of European integration processes in Ukraine.
For Ukraine, cooperation with China opens up new opportunities for international trade and economic development, as China is one of the most influential countries with high economic, scientific and technological development. Thus, the food market in China is not only one of the largest in the world, but is also characterized by the world's fastest growth rates and complex structure. A deep understanding of the detailed features of individual product segments and the Chinese food market as a whole is a key factor in unlocking its potential for Ukraine.
IMPROVING THE DIGITALPRENEUR POTENTIAL OF ECONOMIC EDUCATIONAL STUDENTS OF JENDERAL SOEDIRMAN UNIVERSITY
Authors: Perwita Dyah , Widuri Retno , Afif Nur Choirul , Hadi Prisilia
Published: August 2024

Higher education is the most appropriate level of formal education to prepare generations with an entrepreneurial spirit. The entrepreneurial potential contained in students must be maximized to create new businesses that are in line with current developments. This study aims to improve the potential of digital entrepreneurs (digipreneurs) in economic education students at Jenderal Soedirman University so that they can contribute to reducing the number of unemployed and increasing economic growth through the creation of new jobs, especially in the education sector. This study used a qualitative approach. Data collection techniques using interviews, observation, questionnaires, and documentation. The data source used uses primary data or data obtained directly from data sources without intermediaries. The results of the study illustrate that economics education students have increased potential to become digitalpreneurs in the education sector. Apart from that, this increase in potential reflects concepts and plans to be realized and developed in accordance with current developments. The increase in digitalpreneur business potential among economic education students can be measured using the indicator such as innovativeness, proactiveness, risk taking, competitive aggressiveness, and autonomy.
ANALISIS PENGEMBANGAN EKONOMI KREATIF BERBASIS KEARIFAN LOKAL KHAS SUKU DAYAK
Authors: Sinaga Hotmiana , Eriawaty Eriawaty , Putri Windy Utami
Published: August 2024

Tribe of   have their own habits in managing nature and the environment. These habits formed into a local wisdom. Local wisdom contains universal or comprehensive values seen in everyday life in society, so it's not surprising that a lot of local wisdom has the opportunity to develop into creative industries by adding creativity and innovation, so the purpose of this research is to find out the development of the creative economy based on local wisdom typical of the tribe of the Dayak in the Borneo Accessories City of Palangka Raya.This research uses a qualitative approach with case study methods. The informant of this study is the owner of Borneo Accessories City Palangka Raya business as distributor and supplier. The study was conducted from 1 February to April 25, 2024. The other informant as a supporter is the Mrs. Karlina Batik, as head of the deposit room Disbudpar Kalteng. Interviewing as a primary data collection technique, observation, and documentation as a supporting data collection tool. Results of the research found in this study are that the products produced in Borneo Accessories City Palangka Raya are very diverse ranging from customary clothes, properties to accessories. And for the production process still more to use traditional methods in line with the customs of the past. For its products especially customary clothing has undergone a lot of development in terms of materials and shapes. measures to develop a creative economy based on local wisdom by attending national events in Central Kalimantan and outside the province, conducting routine online and offline promotions, making product variations, ensuring availability of raw materials for processing and production of products, prioritizing product quality, and adjusting price to quality, distributing products, supplying products.
PENGARUH MODEL PEMBELAJARAN PROBLEM BASED LEARNING BERBANTUAN MEDIA MIND MAPPING MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS DAN MOTIVASI BELAJAR
Authors: Kurniawati Rindi , Rahman M Fathur , Sehabuddin Ahmad
Published: August 2024

The implementation of this research was carried out because of the low learning methods used, so that students felt bored in the learning process. The existence of research on the Problem Based Learning learning model with the help of Mind Mapping, namely by forming the experimental class into several small groups using Mind Mapping learning media which makes it easy to do Problem Based Learning learning. This study aims to improve critical thinking skills and learning motivation and conventional learning models. This research is quasi-experimental research with nonequivalent group pretest posttest design. The sample in this study were 72 students. The sampling method used purposive sampling method. Data collection was done by documentation, interviews, observation, and tests. Data analysis techniques by applying paired sample t test and N - Gain test. The results showed that the Problem Based Learning model assisted by Mind Mapping had an effect on improving critical thinking skills and learning motivation of students in class X SMA Negeri 13 Semarang. Based on these findings, the conclusions are: (1) influential to improve critical thinking skills of grade X students, (2) influential to increase student learning motivation Students must be able to play an active role in learning, (3) effectively used to improve critical thinking skills and learning motivation.
PENINGKATAN HASIL BELAJAR SISWA MENGGUNAKAN MEDIA PEMBELAJARAN BERBASIS KONTEKSTUAL DI SMP NUSANTARA INDAH SINTANG
Authors: Odin Yohanes Jefritianus , Relita Dessy Triana , Yulia Suriyanti Yulia
Published: August 2024

The problem in this research is that students are less active in learning, student learning outcomes are low, and students need help to answer questions asked by the teacher, which results in student scores not reaching the minimum completeness criteria (KKM). This research aims to clearly understand the improvement in student learning outcomes by using contextual-based learning media in social studies subjects for class VIII at SMP Nusantara Indah Sintang for the 2023/2024 academic year, with as many as 13 students. The method used in this research is a qualitative descriptive method in the form of PTK classroom action research. Data collection techniques and tools used in this research were observation, interviews, documentation, and tests. The research results showed that the classical value for cycle I was 46.16% and cycle II 92.30%, increasing by 46.14%, while the average value for cycle I was 67.69 and the average value for cycle II was 87.69, rising to 20.00. Thus, students' mastery of the material on advantages and limitations between spaces in demand and supply has increased from medium to high. This means that the use of contextual-based learning media in integrated social sciences learning activities has been proven. Besides that, students' interest in learning shows increased results through students' attention, discipline, activeness, and responsibility in participating in learning, and students can respect their friends well.
PENGARUH STRATEGI PEMASARAN TERHADAP KEPUTUSAN KUNJUNGAN WISATAWAN PADA KELING KUMANG AGROWISATA
Authors: Nanda Erli Lingga Eka Puspa , Astikawati Yunita
Published: August 2024

Tourism is an important sector in the Indonesian economy, especially agrotourism which combines agriculture with tourism. Keling Kumang Agrotourism is a tourist location which is the tourist destination most frequently visited by the people of Sintang. Therefore, this research the study was undertaken with the objective of. obtaining information on the influence of marketing strategies on tourist visits to Keling Kumang Agrotourism. The type of research carried out in this research is quantitative using a causal associative approach. The type of data used is primary data. The population for this research is tourists who have visited and are currently visiting Keling Kumang agrotourism. The sample was 30 tourists using an unintentional checking strategy. The information gathering the strategy was implemented via the execution of predetermined plans and tactics use of a survey using a Likert scale which was tried to investigate speculation. Information from this research was handled using SPSS 26.00. The results of the research show that marketing strategies can be categorized as good with an average classification value of 77. Visiting Decisions are categorized as fair with an average classification value of 73. There is a significant influence by marketing strategy on Visiting Decisions through an R square value of 60, 8, and significant 0.000 < 0.05. This means that there is 39.2 influenced by other factors.
PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF PILAR TAX BERBASIS WEBSITE MENGGUNAKAN SMART APPS CREATOR PADA ELEMEN PERPAJAKAN
Authors: Haliza Nur , Pratiwi Vivi
Published: August 2024

This research was carried out with the aim of describing the media development process, the suitability of the media and students' responses regarding the use of the learning media developed, namely interactive learning media based on website using SAC (Smart Apps Creator) on TAX elements for class XI. This interactive learning media is called PILAR TAX (Smart in Learning taxes). This research uses the ADDIE development model including analysis, design, development, Implementation, dan evaluation. Stesting objects and application of media-based learning website is a class XI student in Financial and Institutional Accounting.  The research results show that the development of interactive learning media is based on website on the tax element, the assessment from material experts was 91.8% in the "Very Appropriate" category, the media expert's assessment was 94% in the "Very Appropriate" category and the language expert's assessment was 96% in the "Very Appropriate" category. Meanwhile, the response of students after using learning media was 96% with the criteria "Very Good". This shows that the interactive learning media product PILAR TAX (Smart Learning Tax) is very suitable for use during the learning process.
PENGEMBANGAN E-BOOK INTERAKTIF BERBASIS APLIKASI BOOK CREATOR PADA MATA PELAJARAN PKK KELAS XI AKUNTANSI
Authors: Avanda Alviona Hewi Briliyant , Pratiwi Vivi
Published: August 2024

This study aims to describe the process of developing an interactive E-book based on the book creator application, analyse the feasibility of interactive E-book s, and students' responses to the use of interactive E-book s developed. This research uses the ADDIE development model which consists of Analysis, Design, Development, Implementation, Evaluation with a website-based interactive E-book output. The instruments used are expert review sheets, expert validation sheets, learner review sheets, and learner response sheets. The results showed that the interactive E-book had been developed in accordance with the ADDIE model. Then the feasibility results show that the validation of the content feasibility component is 87.5% with a very feasible category, the presentation feasibility component is 86.11% with a very feasible category, the language feasibility component is 94% with a very feasible category and the feasibility component is 91.67% with a very feasible category. While the response of students at SMK Negeri 4 Surabaya was 98.32% with a very good category. According to the results of the validation of experts and the response of students, it shows that the interactive E-book produced can be well received for learning activities.
GLOBAL MANAGEMENT AND GLOBAL CULTURE: A BIBLIOMETRIC REVIEW OF BUSINESS PRACTICES AND PERFORMANCE
Authors: Asmaraningtyas Lussy Widia , Sriyono Sriyono
Published: August 2024

This research discusses Global Management and Global Culture in the context of international business development. Through a bibliometric approach, this research evaluates related literature to understand the influence of global management and global culture on business practices and company performance. The main findings highlight publication trends that include digitalization, sustainability, diversity, and the concept of "globalization" as important elements in global management. The theoretical and practical implications of this research demonstrate the complexity of global management and its contribution to international management theory. Practical recommendations include the integration of cultural understanding in business strategy, the enhancement of intercultural competence, and the adoption of sustainable practices. Although this research provides an interesting perspective, there are limitations in the research design and methodology. Therefore, for future research, it is recommended to conduct more in-depth studies on the influence of specific cultures in business practices as well as explore unexplored areas in the literature to provide more comprehensive practical solutions in an increasingly complex global business environment.
PERAN MEDIA SOSIAL DALAM MENINGKATKAN PENJUALAN PUPUK DI PUSAT KOPERASI UNIT DESA RIAU
Authors: Swanda Fajri , Hudi Ilham
Published: August 2024

Currently, the development of the four-point o (4.0) era is the development of digitalization to create a system that is more efficient, flexible, and connected. The progress of internet usage around the world is increasing rapidly. One of the utilizations of technological advances in sales by using social media. The purpose of this research is through social media PUSKUD Riau can build expand networks with customers and business partners. Thus, it is expected to increase sales. This research uses qualitative methods through interviews and direct observation. The data used in this research is to use primary and secondary data. The location of this research was conducted at the Riau Village Unit Cooperative Center (PUSKUD Riau) on Jalan Jendral Sudirman. Where the object of research was conducted to Mr. Dedi Sahputra as Marketing Manager and Mrs. Mitra Rahayu as marketing. Research results show that social media is a promotional event in providing information to KUD-KUD. Utilization of social media can be an advantage for business people and businesses such as PUSKUD Riau so that they are able to sell their merchandise through online in an unlimited manner with the aim of increasing turnover or profit as well as the limitations of the knowledge of researchers who are still beginners so as to have an impact on the results of research that is less thorough and obtain limited information.