bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Bull and Bear Index of Deep Learning to Improve the Indicator Model on Extremely
Short-term Futures Trading
Authors: Chou Hsien-Ming
Published: September 2023

Abstract

Day traders, who trade over time horizons of one day or less, account for around 30% of the total transaction volume at present. Most day traders’ trading strategies are based on their own experiences or news headlines. They may also rely on technical indicators, such as the Relative Strength Index (RSI), to predict short-term trading opportunities and stock index turning points for making selling and buying decisions with respect to stock index futures. This study determined exact RSI indicators, which enhanced the accuracy of short-term stock index prediction. We then tested the proposed model’s performance during an unprecedented crisis such as COVID-19. We used artificial intelligence techniques, such as the SMO algorithm, to evaluate the performance of the proposed model and apply empirical methods on short-term stock index futures datasets to explore the impact of different RSI indicators on the turning points of the stock index futures. The results show that RSI 20 based on regular and COVID-19 periods can enable day traders to achieve higher profits compared to the RSI 30 index.

Keywords: Day traders, Relative strength index, Short-term investment, Artificial intelligence, COVID-19.
Predictors of Nursing Staff Turnover Intentions - Evidence from Primary Care Organizations in Taiwan
Authors: Lee Shih-Nien
Published: September 2023

Abstract

The direct contact between nursing staff and patients during the COVID-19 epidemic increased their turnover tendency due to severe cases, mortality, disease uncertainty, and increased care giving stress during the outbreak, which had a significant impact not only on nursing staff but also on patients and hospitals. It is important for hospital administrators to examine the factors related to nursing staff and turnover tendency. In this study, we investigated the effects of personality traits, job satisfaction, organizational commitment, and turnover tendency by examining the correlation theory among frontline health care workers. The main findings showed that (1) personality traits had a significant positive relationship with organizational commitment; (2) job satisfaction had a significant positive relationship with organizational commitment; and (3) organizational commitment had a significant positive relationship with turnover tendency. The results of the study contribute to relevant literature and have guiding implications for the management of human resources in healthcare service organizations.

Keywords: Personality Traits, Organizational Commitment, Turnover Intention, Job Satisfaction.
Influência da glicose na regulação do metabolismo de xilose em Spathaspora passalidarum
Authors:   , Ribeiro Lílian Emídio
Published: September 2023

A levedura Spathaspora passalidarum possui grande potencial de converter glicose e xilose de materiais lignocelulósicos em bioetanol. No entanto, essa levedura utiliza esses açúcares de forma sequencial, sendo a glicose consumida preferencialmente em relação à xilose. O presente trabalho buscou identificar as principais formas que glicose interfere no metabolismo de xilose em S. passalidarum. Primeiramente foi avaliado a influência da glicose no consumo de xilose, produção de etanol, expressão de genes e atividade das enzimas chave para assimilação de xilose, em condições de aeração e de limitação de oxigênio. Os principais resultados obtidos mostram que a glicose inibe o consumo de xilose dessa levedura, independente da condição de oxigenação e da sua concentração extracelular. Os genes que codificam as enzimas xilose redutase (XR), xilose desidrogenase (XDH) e xiluloquinase (XK) foram menos expressos quando glicose estava presente no meio, indicando a ocorrência de repressão por glicose no metabolismo de xilose. Porém, testes de crescimento utilizando o análogo de glicose 2-deoxiglicose (2DG) revelaram a ausência de repressão catabólica, embora a 2DG atrase o consumo de xilose quando presente no meio. Assim, é possível que a interferência da glicose no metabolismo da xilose de S. passalidarum possa estar ocorrendo a nível de transporte. Para entender a influência da glicose no transporte de xilose primeiramente identificamos potenciais transportadores de glicose e xilose no genoma dessa levedura. O perfil de expressão dos genes que codificam os potenciais transportadores, sugere que essa levedura possui vias de detecção e regulação transcricional de transportadores de açúcares. Para caracterização funcional, quatro prováveis transportadores foram selecionados e expressos na linhagem de S. cerevisiae DGLK1. Essa linhagem possui a deleção dos principais transportadores de hexose (hxt1-hxt7 e gal2) e, portanto, somente será capaz de crescer em meio contendo glicose ou xilose como fonte de carbono, através da expressão de um transportador heterólogo. Apenas um dos transportadores testados foi capaz de restaurar o crescimento de S. cerevisiae DGLK1 em meio sólido com xilose ou glicose. A estrutura proteica deste alvo é característica de um transportador de açúcar e as análises de docking mostraram que a glicose tem maior afinidade de ligação a esse transportador, comparado à xilose e 2DG. Dessa forma, sugerimos que a glicose interfere no metabolismo de xilose através da inibição do transporte de xilose, por meio da competição pelo mesmo transportador. Além disso, a glicose controla, por mecanismos ainda desconhecidos, a expressão dos genes que codificam os transportadores de açúcares e os genes das principais enzimas do metabolismo da xilose. Assim, estes pontos de regulação precisam ser investigados e contornados para obter a máxima eficiência no consumo simultâneo destes açúcares por S. passalidarum. Palavras-chave: Spathaspora passalidarum. Cofermentação. Repressão por glicose
KORXONA MARKETING STRATEGIYASIDA RAQAMLI STRATEGIYADAN FOYDALANISH USULLARI VA AFZALLIKLARI
Authors: Axmedova Nazokat
Published: September 2023

Ushbu maqolada, raqamli strategiya korxonalar uchun marketing strategiyasining muhimligi va uning roli tahlil qilinadi. Maqolada, raqamli strategiya korxonalarining marketingda raqamli analitika, ma'lumotlar analitikasi, ma'lumotlar tahlili, ma'lumotlar vizualizatsiyasi va ma'lumotlar ustida asoslangan qarorlar qabul qilishning ahamiyati ko‘rsatiladi. Shuningdek, maqolada raqamli strategiya korxonalar uchun marketing strategiyasini amalga oshirishning muhim ustuvorliklari, muvaffaqiyat faktorlari va qiyinchiliklari ham ko‘rsatiladi.
ILMIY MUAMMOLARNI HAL ETISHDA BAHS-MUNOZARALARNING TUTGAN O‘RNI
Authors: Тurabova Sevara
Published: September 2023

Mazkur maqolada ilmiy bahs-munozaraning ilmiy bilish jarayoni va amaliy faoliyat sohasida vujudga keladigan muammolar yechimini topish borasida maqbul usul sifatidagi funksional jihatlari tahlil qilingan. Shuningdek, argumentlash nazariyasining falsafiy muammolari orasida bahsning kommunikatsiya vositasi sifatida ilm-fan va ijtimoiy-siyosiy hayot tizimidagi integratsiyasini o‘rganishning dolzarbligi yoritilgan
O‘ZBEK XALQ QO‘SHIQLARIDA YUZ SOMATIZMINING BADIIY TALQINI
Authors: Hamroyeva Dilfuza
Published: September 2023

Ushbu maqolada o‘zbek xalq qo‘shiqlarida yuz somatizmining  badiiy talqini, poetik obrazlar bilan ifodalanishi, totemistik tushunchalar, kultlar bilan bog’liq jihatlari ochib berilgan.
ПОНЯТИЕ И ОСОБЕННОСТИ ЭКОЛОГИЧЕСКОЙ ПОЛИТИКИ РЕСПУБЛИКИ УЗБЕКИСТАН В КОНТЕКСТЕ УСТОЙЧИВОГО РАЗВИТИЯ
Authors: Файзиев Шухрат
Published: September 2023

В статье анализирована роль правового обеспечения экологической политики Республики Узбекистан в контексте устойчивого развития. На основе научно-правовых суждений обосновывается основные направления экологической политики государства в сфере охраны окружающей среды. Автор уделяет особое внимание на определение таких понятий как: «экологическая политика государства» и «правовое обеспечение экологической политики государства».
KURASH BILAN SHUG‘ULLANUVCHI TALABA SPORTCHILARDA TAYYORGARLIK BOSQICHLARINI KUN VA HAFTALIK MIKROTSIKLLARDA MASHG‘ULOT YUKLAMALARINI OPTIMAL ME’YORLASH
Authors: Masharipov Ravqat
Published: September 2023

Kurashda tezkor rejalashtirishda yuklamalarni meʼyorlashni, tajribaning keyingi bosqich mashg‘ulot vazifalarida yuklamalar hajmi boʼyicha uning quyidagi tavsiflari yo‘nalishi va ixtisoslashganligini hisobga olgan holda me‘yorlashni ishlab chiqishdan iborat bo‘ldi. Tajribalar natijalariga ko‘ra,  talaba-kurashchilar uchun tayyorgarlik jarayonidagi mashg‘ulot yuklamalarining umumiy hajm rejasi ishlab chiqildi va tajriba guruhi amaliyotida qo‘llanildi.
XORAZM XALQ O‘YINLARI
Authors: Niyozmatov Anvar
Published: September 2023

Bu maqolada Xorazm xalq o‘yinlarining o‘quvchilarni  ma’naviy tarbiyalashdagi pedagogik-psixolog o‘rni yoritilgan. Shu bilan birga, xalq o‘yinlarining insonni dastlabki hayotga tayyorlash jarayonida tarbiyaning muhim omili ekanligi ko‘rsatilgan. Xalq o‘yinlari oʻquvchilarning xalqimizning bir necha yillik madaniy boyliklari haqidagi tasavvurlarini ma’lum darajada kengaytirib kelajak hayotda oʻz oʻrnini topishga yordam berishi ochib berilgan.
The Legal Regime of Anti-Crisis Regulation in the Healthcare
Authors: Tsomartova Fatima V.
Published: September 2023

Introduction. The understanding of crisis situations in many of their varieties, including those affecting the health of the population, is shifting from temporary and exceptional one-time events to long-term processes that pose serious challenges to the rule of law and require an adequate legal response. Under such circumstances, the usual health regulators, designed for the normal state of social relations, turn out to be non-functional. In this regard, the problem of scientific development of a special legal mechanism for anti-crisis management aimed at preventing, ensuring preparedness, effective response and liquidation of the consequences of crisis situations in the healthcare sector is being actualized.
Materials and methods. The methodological basу of the study included general scientific (dialectical, logical, systemic, historical, sociological, statistical), and private scientific methods of legal science (formal legal, historical legal and comparative legal). The empirical base of the study was domestic and foreign legal acts, law enforcement practice, and legal doctrine.
Results. There were identified and characterized,main features of the legal mechanism of anti-crisis management in the healthcare sector including the interdependence of risks in the healthcare sector and the need for a comprehensive regulatory impact on them, the normalization of anti-crisis regulation of the health of citizens, some dejuridization of the industry, a change in the ratio of individual and public interests, acceleration digitalization and intensification of legal experiments in healthcare.
Limitations. Due to the objective novelty of the problem under consideration the study is somewhat limited in terms of reviewing the reports on the relevant topic.
Conclusion. In modern conditions of permanent instability, there is a tendency to form the so-called anti-crisis standard for protecting the health of citizens as a special comprehensive intersectoral perpetual legal regime adapted to exceptional threats to the life and health of citizens.
Tools for medical manipulation: the evolution of use, treatment and disinfection (literature review)
Authors: Milushkina Olga Yu. , Timerzyanov Marat I. , Vasiliev Denis E.
Published: September 2023

Many factors contributed to the improvement of the quality and safety of medical services, including the development of medical instruments and methods of their treatment and disinfection. This article summarizes a brief history of instruments for medical manipulation and the development of methods of their processing over the world and Russia.
The purpose of the study is to review and generalize the development of surgical instruments used for medical manipulations, including autopsy, their treatment, and disinfection. A comprehensive literature search was conducted for references on the topic of the article and subsequent analysis of publications. Systematic search of scientific papers was carried out using several search engines: PubMed, RSCI, Google Scholar, CyberLeninka.
The progress of forensic medical examination is largely related to the result of the development of medical instruments, methods, and modes of their processing. Surgical instruments existed at the dawn of mankind, and their evolution corresponds to the degree of development of medical science and practice. The use of disinfectants for the treatment of medical instruments dates back hundreds of years. Disinfection of sectional instruments is of paramount importance to ensure infection safety. We have accumulated some experience in using disinfectants. Success depends solely on the use of effective methods and disinfection, in recent years, the treatment and disinfection of instruments has been supplemented with modern methods. Prospects for further improvement of the results of forensic medical examination are necessarily associated with the development of tools for medical manipulation and their processing.
Optimized machine learning based predictive diagnosis approach for diabetes mellitus
Authors: AKKUR Erkan , TÜRK Fuat
Published: September 2023

Aims: Diabetes mellitus is a metabolic disease caused by elevated blood sugar. If this disease is not diagnosed on time, it has the potential to pose a risk to other organs and tissues. Machine learning algorithms have started to preferred day by day in the detection of this disease, as in many other diseases. This study suggests a diabetes prediction approach incorporating optimized machine learning (ML) algorithms.

Methods: The framework presented in this study starts with the application of different data pre-processing processes. Random forest (RF), support vector machine (SVM), K-nearest neighbor (K-NN) and decision tree (DT) algorithms are used for classification. Grid search is utilized for hyperparameter optimization of algorithms. Different performance evaluation measures are used to find the algorithm that best predicts diabetes. PIMA Indian dataset (PID) is chosen for testing the experiments. In addition, it is investigated to what extent the attributes in the data set affect the result using Shapley additive explanations (SHAP) analysis.

Results: As a result of the experiments, the RF algorithm achieved the highest success rate with 89.06%, 84.33%, 84.33%, 84.33% and 0.88% accuracy, precision, sensitivity, F1-score and AUC scores. As a result of the SHAP analysis, it is found that the “Insulin”, “Age” and “Glucose” attributes contributed the most to the prediction model in identifying patients with diabetes.

Conclusion: The hyperparameter optimized RF approach proposed in the framework of the study provided a good result in the prediction and diagnosis of diabetes mellitus when compared with similar studies in the literature. As a result, an expert system can be designed to detect diabetes early in real time using the proposed method.
Evaluation of the association of anti-thyroid peroxidase with antinuclear antibodies and different antinuclear antibodies patterns
Authors: TOGAY Alper , BASOK Banu Isbilen , ÇOLAK Ayfer , YILMAZ Nisel
Published: September 2023

Aims: To investigate the relationship between anti-thyroid peroxidase (TPO), a marker for Hashimoto’s thyroiditis, and antinuclear antibodies (ANA) and ANA patterns, biomarkers for systemic autoimmune diseases.

Methods: In this study, ANA and anti-TPO test results, obtained in our hospital laboratory between 2019 and 2022, were retrospectively evaluated. ANA was detected by the indirect immunofluorescence antibody method using commercial HEp-20-10 cell substrates and anti-TPO was determined by the sandwich immunoassay method using a commercial immunoassay analyzer.

Results: A total of 1750 patients’ results were analyzed. ANA was positive in 28.7% of anti-TPO-positive patients and 19% of anti-TPO-negative patients. While 6.4% (112/1750) of patients were positive for both ANA and anti-TPO, both test results were negative in 62.85% of patients (p
The importance of serum estrone level in cases of chronic venous insufficiency in the lower extremity
Authors: BENDER Rukiye Ada , ŞİMŞEK Baran
Published: September 2023

Aims: Chronic venous insufficiency (CVI) is a condition characterized by abnormal venous flow dynamics in the lower limbs and is associated with various risk factors such as pregnancy, age, obesity, and high estrogen states. One of these estrogens, estrone, is known to have cardioprotective effects. The study aimed to evaluate the relationship between estrone levels in women with CVI and healthy women.

Methods: Clinical and laboratory data from 39 women with CVI and 31 healthy women without CVI were collected. All participants underwent spectral Doppler examinations and combined B-mode imaging to assess the severity of CVI.

Results: The results showed a statistically significant increase in the diameter of the vena saphenous magna in the CVI group compared to the healthy control group (p
Long-term outcomes of percutaneous release technique or open for trigger finger in diabetic patients
Authors: DÜNDAR Abdulrahim , KAYA Şehmuz , İPEK Deniz
Published: September 2023

Aims: Trigger finger is seen more often in diabetic patients and can lead to more serious postoperative complications compared to non-diabetic patients. The aim of this study was to compare the outcomes of open and percutaneous release techniques in diabetic patients.

Methods: This retrospective study included 62 patients who met the study criteria. Of these patients, 32 underwent open release surgery and 30 underwent percutaneous release with an 18-gauge needle. The patients were evaluated retrospectively in respect of the data on first presentation preoperatively and at postoperative follow-up examinations at 3 weeks, 6 months and 1 year. A retrospective examination was made of the demographic data, Visual Analog Scale (VAS) scores preoperatively, at 6 and 12 months postoperatively, recurrence rates at the end of 6 months and 1 year, the Quinnell grading scale at the end of 1 year, wound site infection, tendon damage and neurovascular complications. VAS scores and the Quinnell grading scale were used for clinical evaluation.

Results: The data of a total of 62 patients were statistically analyzed in the study, with 32 (51.6%) in the Open group and 30 (48.4%) in the Percutaneous group. The mean age of the patients was 58.97±7.51 (min-max: 45-72) years. The distributions of trigger finger and Quinnell grading system scores were statistically similar between the groups (P=0.974, P=0.279, respectively). The recurrent triggering rate at the 6th and 12th month was significantly higher in the Percutaneous group (P=0.049, P=0.049, respectively). The average return to work duration in the Percutaneous group (1.70±0.75) was significantly shorter than that in the Open group (3.88±1.21) (P
The effect of occupational therapy on upper extremity function and activities of daily living in hemiplegic patients
Authors: DOĞAN Ayşe Gülşen
Published: September 2023

Aims: We aimed to investigate the effectiveness of occupational therapy (OT) added to traditional rehabilitation treatments on activities of daily living and upper extremity functions in hemiplegic patients in this study.

Methods: This study was carried out within eighty hemiplegic patients. In the evaluation of the patients before the therapy, age, gender, body mass index (BMI), occupation, education, duration of stroke, stroke etiology, symptomatic side, the presence of systemic diseases and dominant hand data were recorded. The patients were randomized into two groups according to the sealed envelope method. While standard rehabilitation (ST) (50 minutes five days a week for 6 weeks) was applied to the first group, ST (50 minutes five days a week for 6 weeks) and OT (40 minutes three days a week for 6 weeks) were applied to the second group. Functional Independence Scale (FIM), Fugl-Meyer Upper Extremity Assessment of Motor Recovery Scale (FMA) and Action Research Arm Test (ARAT) were evaluated before the treatment and on the 45th day after the end of the treatment.

Results: Our study included 35 male and 45 female patients. There was no significant difference between the two groups in terms of age, gender, symptom duration and stroke etiology. FIM, ARAT and FMA values were found to be increased in both groups compared to pre-treatment (ST; FIM p=0.003, ARAT p=0.011, FMA p= 0.002 OT; FIM p=0.023, ARAT p=0.024, FMA p= 0.012 ). While there was no significant difference in terms of FIM, ARAT and FMA values before treatment in comparisons between groups, all parameters were found to be significantly increased in the OT group compared to ST on the 45th day of treatment (FIM p=0.017, ARAT p=0.021, FMA p= 0. 004).

Conclusion: In this study, OT was applied three times a week for 40 extremity dexterity. While the increase in FIM, FMA and ARAT was significant after treatment in both groups, the increase in the OT group was higher when compared to ST. The results of our study show that both ST and OT are effective in stroke rehabilitation. In addition, it has been clearly proven that more effective results are obtained in upper extremity functions with OT added to ST.
A noteworthy prognostic marker in extensive small cell lung cancer: lymphocyte/C-reactive protein ratio
Authors: ÖZTÜRK ERGÜR Figen , ÖZTÜRK Ayperi , UZEL ŞENER Melahat , SAYMAZ Zeynep Tilbe , MUTLU Nihal
Published: September 2023

Aims: We aimed to investigate the pre-treatment prognostic significance of lymphocyte/C-Reactive protein ratio (LCR), one of the inflammatory factors, in patients with extensive-stage small cell lung cancer (SCLC).

Methods: Medical records of 514 patients who were diagnosed with extensive-stage SCLC between 2010 and 2020 were examined retrospectively. LCR was calculated using the blood test results prior to chemotherapy.

Results: The mean survival time for extensive-stage SCLC is 6 months (5.3-6.7). A statistically significant difference exists between limited and extensive stages in terms of median overall survival (OS) (p
Investigation of the synovial fluid pro-inflammatory cytokines and clinical findings in disc displacements of TMJ
Authors: YILMAZ ASAN Canay , BAYINDIR Şeyma , DEMİRBAŞ Ahmet Emin , BARLAK KETİ Didem , KÜTÜK Nükhet
Published: September 2023

Aims: Temporomandibular disorders (TMD) are common musculoskeletal disease that affects the soft tissues and bone structures of the temporomandibular joint (TMJ). Inflammatory mediators play a critical role in the etiology of TMD by affecting various molecular mechanisms. This study aims to investigate the effect of pro-inflammatory cytokines on TMJ internal derangements and evaluate the relationship between clinical features.

Methods: Patients who underwent arthrocentesis because of TMD were included in this study. Patients were divided into 2 groups according to anterior disc displacement with reduction (Group 1) and without reduction ( Group 2). Clinical findings before and after the arthrocentesis were evaluated retrospectively. Synovial fluid TNF-α, IL-1β, and IL-6 levels were analyzed with the ELISA method.

Results: A total of 28 patients were included, with 15 patients in Group 1 and 13 patients in Group 2. All patients were female with an average age of 30.75±14.9. The average pre-operative pain score was 6.6±1.95 in all patients. After the arthrocentesis, the average pain score was 2.0 ( 1.0 - 2.5) and the difference was significant (p
Which factors are predicting the mortality in patients with COVID-19 in the intensive care unit?
Authors: PARPUCU Ümit Murat , TURAN Sema , CANKAR DAL Hayriye , TOSUN Damla , YALNIZ Kudret Yasemin , AYDEMİR Semih , ÖZTÜRK KAZANCI Dilek
Published: September 2023

Aims: COVID-19 infection is a global health problem; clinical and laboratory parameters have been developed to predict this disease-related mortality/morbidity. Some of these parameters are clinical parameters, while some are laboratory parameters. This study aims to determine whether Acute Physiology and Chronic Health Evaluation (APACHE) II, Glasgow Coma Scale (GCS), age, presence of comorbidity, and absolute lymphocyte count effectively predict mortality in patients admitted to intensive care unit (ICU) due to COVID-19.

Methods: We have included 108 PCR-positive COVID-19 patients admitted to the ICU between 1 October and 31 November 2020 in our research. Demographic characteristics of all patients, APACHE II values within the first 24 hours of admission to ICU, the GCS, the presence of comorbidity, lymphocyte count during ICU admission, duration of ICU stay, and the mortality rates were recorded.

Results: The average age of 108 individuals evaluated in the study was 67±13.61 years, and 56.5% of the patient group consisted of the geriatric age range. Seventy (64.8%) of the patients were female, eighty-nine (82.4%) patients had at least one comorbidity. In the multivariate analysis, it was determined that lymphocyte value, APACHE II score, and the presence of any comorbidity are independent prognostic factors for mortality when accepted to ICU.

Conclusion: In our study, we have determined that age, APACHE II value, presence of comorbidity, and baseline lymphocyte counts are independent predictors of mortality.
The role of the TAPSE/PASP ratio in the prediction of paroxysmal atrial fibrillation in patients with acute ischemic stroke
Authors: ÇAKMAK Tolga , ŞAFAK Özgen
Published: September 2023

Aims: Atrial fibrillation (AF) remains the most prevalent cause of cardioembolic stroke. Paroxysmal AF (PAF) is often difficult to be diagnosed and is sometimes first detected during embolic stroke. Yet, TAPSE and PASP can be easily revealed in routine transthoracic echocardiography (TTE). Then, the TAPSE/PASP ratio is often shown to have prognostic significance in many cardiac disorders. Nevertheless, the insufficient scholarly knowledge of the relationship between this ratio and the development of PAF became the primary motive of the present study.

Methods: We carried out this study with 114 patients experiencing acute ischemic stroke without a previous diagnosis of AF. We noted down the patients’ blood parameters and prescribed drugs and calculated TAPSE/PASP ratio relying on their TTE findings. We also recorded the 24-hour heart rhythm findings of each patient through Holter monitoring. After categorizing PAF attacks (i.e.,PAF attack was (not) observed), we explored any statistical relationship between the TAPSE/PASP ratio and the presence of PAF.

Results: The findings revealed a significant difference between the TAPSE/PASP ratios between the groups with PAF (0.62±0.07) and without PAF (0.77±0.08). Moreover, the receiver operating characteristic (ROC) curve analysis yielded the TAPSE/PASP ratio to demonstrate a diagnostic value in predicting PAF (area under the ROC curve [AUC]=0.89;82.7%; p
ANALISIS KEBERADAAN AIR TANAH MENGGUNAKAN METODE GEOLISTRIK DALAM SKALA LABORATORIUM
Authors: Zannah Hildatul , Ahadah Salfa Zahroh , Syahdilla Muhammad Ivan , Ulfah Ana Zuyyina , Anggraeni Firdha Kusuma Ayu
Published: September 2023

Air tanah memiliki peranan yang penting bagi manusia dalam kehidupan sehari-hari karena dapat dimanfaatkan dalam setiap hal. Keberadaan air tanah yang melimpah terletak pada lapisan-lapisan bawah permukaan bumi diperlukan suatu metode untuk memudahkan manusia mengetahui keberadaan air tanah tersebut. Penerapan geolistrik resistivitas dalam menentukan keberadaan air tanah di bawah permukaan bumi dapat dilakukan dengan menggunakan konfigurasi schlumberger. Metode yang digunakan pada penelitian ini yaitu dengan menggunakan metode eksperimen skala laboratorium dengan menerapkan metode geolistrik resistivitas. Studi literatur dilakukan pada tahap awal dalam melakukan penelitian ini. Setelah itu, dilakukan pengambilan data penelitian. Hasil dari data penelitian tersebut kemudian diolah dengan menggunakan software IPI2WIN. Hasil yang diperoleh setelah dilakukan pengolahan data dengan menggunakan software IPI2WIN dapat diketahui bahwa pada alat geolistrik skala laboratorium didominasi oleh lapisan batuan dengan nilai resistivitas sebesar 1000Ωm. Melalui hasil penelitian yang didapatkan, maka dapat diketahui bahwa alat geolistrik skala laboratorium dapat digunakan untuk menganalisis keberadaan air tanah.
İleri Glikasyon Son Ürünleri (AGE) ve Polikistik Over Sendromu İlişkisi
Authors: AŞIK Büşra Nur , EDE ÇİNTESUN Elif
Published: September 2023

İleri glikasyon son ürünleri (AGE), arginin ve lizin gibi serbest amino asit grupları ile indirgen şekerlerin serbest karbonil grubu arasındaki enzimatik olmayan Maillard reaksiyonu yoluyla oluşan heterojen ve karmaşık bileşikler grubudur. Fizyolojik koşullarda tüm dokularda ve vücut sıvılarında AGE’ler oluşabilmektedir. Ekzojen olarak vücuda beslenme yoluyla da alınabilmektedir. Normal metabolizmanın bir parçası olarak vücutta oluşan AGE’ler dolaşımda yüksek düzeylere ulaştığında sağlık üzerinde olumsuz etkiler gösterebilmektedir. Bu olumsuz etkilerini; vücut proteinleri ile çapraz bağ yaparak veya hücre yüzey reseptörlerine bağlanarak göstermektedir. Bunun sonucu olarak; AGE’ler, oksidatif stres ve inflamasyonun gelişiminde rol oynayabilmektedir. AGE’ler; diyabet, insülin direnci, obezite, kardiyovasküler hastalıklar, nörodejeneratif hastalıklar, böbrek hastalıkları, infertilite ve polikistik over sendromu (PKOS) ile ilişkilendirilmiştir. PKOS’lu kadınlar; obezite, insülin direnci ve yumurtalık disfonksiyonuna sebep olan yüksek serum AGE düzeylerine sahiptir. AGE’lerin, vücutta hormonları inhibe etmesi, hormonları taklit etmesi, hormonların aşırı salınımına yol açması, oksidatif stres ve inflamasyona sebep olması ile PKOS’la ilişkili olabileceği düşünülmektedir. Güncel çalışmalar, diyet kaynaklı AGE’lerin (dAGE), PKOS’lu kadınlarda metabolik bozukluklara yol açabileceğini göstermektedir. PKOS semptomlarını yönetmek ve PKOS’la ilişkili hastalıkları önlemek amacıyla; diyet AGE içeriğinin azaltılmasının yeni bir tedavi yaklaşımı olabileceği öne sürülmektedir. Bu derlemede; AGE ve PKOS ilişkisinin güncel veriler eşliğinde değerlendirilmesi amaçlanmıştır.
Gender Differences in the Use of GeoGebra and Grapes in Teaching Mathematics in Secondary Schools in Kenya.
Authors: Kipngetich Langat Richard , Wekesa Mukwa Chris , Kiprop Too Jackson
Published: September 2023

This study was carried out to examine the gender differences in academic achievement in mathematics by use of Grapes and GeoGebra graphing softwares. The objective of the study was to establish whether the use of GeoGebra and Grapes can improve the performance in mathematics for both boys and girls. This study was guided by Technology Acceptance Model (Davis, 1989). Technology Acceptance Model (TAM) explains computer-usage behavior that relates to reasons why some people use computers and their attitudes towards them. This study adopted Solomon four group experimental research design. The respondents were selected using both stratified and simple random sampling. Data was collected through the use of students’ questionnaires, pre-test and post-test. Analysis of data was done using both descriptive and inferential statistics. For descriptive statistics, frequency tables and means were used. Anova and t-test were employed for the inferential statistics. The study found out that boys and girls had the same academic achievement when taught using Grapes and GeoGebra. It is recommended that the teaching and learning of mathematics should involve a lot of practical activities which engage both sexes of the learners equally throughout the lesson .This will make the learners to develop a lot of problem solving skills and critical thinking skills which required in mathematics.
Vaksin SARS-CoV-2: Tinjauan Kepustakaan
Authors: Dominicus Husada
Published: September 2023

Pandemi virus Systemic Acute Respiratory Syndrome–coronavirus-2 (SARS-CoV-2) belum dapat dihentikan hingga pertengahan Juni 2020. Kesulitan menemukan obat mujarab untuk penyakit ini membuat kehadiran vaksin menjadi sangat berharga. Pada saat ini ada lebih dari 100 kandidat vaksin di seluruh dunia, dengan sedikitnya 10 di antaranya telah mulai menjalani uji klinik pada manusia. Vaksin pada tahap terjauh adalah dari University of Oxford yang telah memasuki fase 3. Pendekatan yang digunakan dalam pembuatan vaksin berlainan, dan beberapa cara belum pernah digunakan sebelumnya. Sebagian vaksin dalam penelitian adalah vaksi yang awalnya ditrujukan untuk SARS-CoV yang lama maupun Middle East Respiratory Syndrome-coronavirus (MERS-CoV). Target utama pada umumnya adalah protein spike S. Beberapa kendala perlu diperhatikan dalam upaya penelitian vaksin ini, seperti belum pernah adanya vaksin untuk virus corona, fenomena antibody-dependent enhancement (ADE), serta kemungkinan imunopotensiasi. Di Indonesia ada 4 lembaga yang juga meneliti vaksin, ditambah 3 lembaga lain yang bekerja sama dengan institusi di luar negeri untuk langsung masuk dalam fase uji klinik. Setelah vaksin ditemukan perlu adanya jaminan kesetaraan dalam memperoleh akses antar berbagai negara.
Theoretical foundations creation of an ekranolet with a special geometry of the wing and fuselage adapted on the flyover
Authors:   Independent researcher, Zakuraev A. F.
Published: September 2023

The article briefly outlines foundations of the theory of creating an ekranolet with a special geometry of the wing and fuselage on an elliptical flyover. The issues of stability and controllability in the lateral perturbed motion of the ekranolet are considered, the determination of the conditions and the influence of aerodynamic characteristics under which the oscillatory stability of the ekranolet is ensured at all ranges of flight modes.
The play «Andemirkan» in North Caucasian dramaturgy: problems of attribution and dating
Authors:   Kabardino-Balkarian State University named after H. M. Berbekov, Abazov A. Ch.
Published: September 2023

The article is devoted to the problem of study and inclusion in the scientific turnover of previously unknown information related to The article deals with the problem of studying the previously unknown information related to the history of creation of unfinished and unannotated fiction text «Andemirkan» in North Caucasian dramaturgy. The article touches upon the issues of determining the author (attribution) of the investigated written source. The study of this topic through the inclusion of new sources related to the history of novice The study of this topic will help to fill the gap in the reconstruction of the most complex period in the development of the North Pole. The study of this subject will help fill the gap in reconstructing the development of North Caucasian literature in the second half of the 1930s. At the same time. At the same time, a profound analysis of the text itself, taking into account the new sources identified for its attribution and The authors of the play have also found new sources for attributing and dating the text. The analysis and study of dramaturgical works – texts about Andemirkan – have multifaceted significance, are carried out with the aim of solving both practical and theoretical problems. We are currently working on We are currently working on the preparation and inclusion of this material into the modern research context. This article also provides biobibliographical information about the authors of works that, to one degree or another, have addressed the This article also provides bibliographic information about the authors of works that to a greater or lesser degree have touched upon the topic in question. The text has been analyzed from the point of view of idea, composition structure, artistic and stylistic features, the manner of speech of the characters, genre and species features and other noteworthy features. Establishing the time, place, and other circumstances of the creation of the written testimonies will contribute to a more full identification of collegiate and friendly and creative ties not only between the repressed Kabardian writer Abdul Pshenokov and Ossetian playwright Agubekir Bolayev (Kubatiev), but also the creative collaboration of А. Bolaev with young Kabardian playwrights...
Maykop toponymy with regional chrono- and ethno- color
Authors:   Maykop State Technological University, Khuako F. N.
Published: September 2023

The present article discusses the semantic and chronicle specificity of such a lexical category as the names of city streets on the example of the capital of the Republic of Adygea, the city of Maykop in the Russian Federation. The subject that is part of the country, with its toponymy, often and in most cases reflects state historical events, perpetuates federal (sometimes, national) heroes, or fulfills the corresponding metropolitan naming instructions. The final conclusion here is the author's conclusion about both the informative and emotionally pathetic functional role of the toponymic material considered in the article.
Super-Intelligent Machines - Analysis of Developmental Challenges and Predicted Negative Consequences
Authors: Aithal P. S.
Published: September 2023

Purpose: There is a large hue and cry on achieving Super-Intelligence Machines (SIMs) using artificial intelligence technology and its adverse effect on society initially started both academia and industries which is now percolating to society and governance of many countries. It is interesting to study the possibility of the development of Super-Intelligent Machines (SIMs), their predicted abilities to surpass human intelligence in any general or particular area, and also the predicted negative consequences on human life or dangers of using such machines in the sustainability of human life on earth. Methodology: Used exploratory research method to analyse the issue of Achieving & Consequences of Super-Intelligent Machines by collecting relevant & published information using Google search engine, Google Scholar search engine, and Various Artificial Intelligence generating engines like ChatGPT & Bard, etc. The information is analysed using SWOC and ABCD analysis frameworks from various stakeholders’ points of view. Findings: As artificial intelligence continues to advance rapidly, the prospect of creating super-intelligent machines that surpass human cognitive abilities raises crucial questions and concerns. This comprehensive study aimed to analyse the developmental challenges involved in achieving super-intelligence machine, examining the ethical and societal implications, as well as predicting potential negative consequences that might arise from the widespread deployment of such machines. The development roadmap and consequences of such development of SIMs in society are analysed by means of their strengths, weaknesses, opportunities, and challenges. The advantages, benefits, constraints, and disadvantages of realizing SIMs are also analysed. Finally, certain Suggestions for precautions on consequences on human life are included as percussion for the use of such high-tech systems. Originality/Value: By exploring the risks and benefits associated with super-intelligent machines, this research paper seeks to foster a deeper understanding of the transformative role they might play in shaping our future and to offer insights that can guide policymakers, researchers, and industry leaders in making informed decisions to harness this technology responsibly. Type of Paper: Exploratory Research.
Research Progress of Hemostatic Materials based on Tannic Acid
Authors:   School of Materials Science and Engineering, Dalian University of Technology, Pan XU , Xufeng DONG ,   School of Materials Science and Engineering, Dalian University of Technology, Min QI ,   School of Materials Science and Engineering, Dalian University of Technology
Published: September 2023

Tannic acid is a class of plant polyphenols, which widely exists in natural herbs such as Chinese gallnut and tea. It has the functions of hemostasis, anti-inflammatory, antibacterial, and antioxidant. Its structure is rich in catechol groups and exhibits extremely high reactivity, which can not only interact with blood cells and plasma proteins to promote vasoconstriction and blood coagulation, but also combine with biological macromolecules, metal ions and synthetic polymers to prepare hydrogels, sponges, coatings, particles, or other forms; it can also solve many problems related to bleeding, infection, and oxidation during wound healing, and has the potential to prepare high-performance hemostatic materials. Recently, researchers have reported various tannic acid hemostatic materials that are simple to prepare and have excellent properties, attracting widespread attention from scholars at home and abroad. Therefore, this paper focuses on the hemostatic properties of tannic acid, and summarizes the hemostatic mechanism of tannic acid and the design ideas of related hemostatic materials; summarizes the common tannin hemostatic materials were summarized based on material types and product characteristics; finally, discusses the possible limitations and future development directions, to provide a reliable basis for in-depth research on tannic acid hemostatic materials.
A Cross Sectional Descriptive Study for Estimation of Stature from Foot Length in South Indian Population
Authors: Kumar S V , Shruthi K , Anand P B , Tejas J
Published: September 2023

Identification can be done by a myriad of methods and of them includes the measurement of stature by foot length The Study population includes the faculty and students of a tertiary medical care college and hospital and the residents of a district in South India between the ages group of 21-40 years. 200 members consisting of 100 male and 100 female were chosen by stratified random sampling. The height was measured by using standard height measuring instrument and foot length by a vernier calliper. A highly significant correlation was found between Stature and RFL(r=0.811) with the strength of association being more in males (r=0.677) than females (r=0.592). Ahighly significant correlation was also found between Stature and LFL (r=0.823) with the strength of association again being more in males (r=0.707) than in females (r=0.582). Between the two feet, the stature showed highly significant strong correlation with LFL (r=0.823) 2 when compared to RFL (r=0.811). By comparing the r and r values in different study groups it is seen that pooled sample shows better correlation than individual sex. Regression equations were developed for individual sex and also for the pooled data. Stature showed a highly significant positive correlation with both foot lengths with the RFL exhibiting a slightly stronger association. Regression equation for stature developed in this study with respect to the pooled data exhibited a better goodness of fit for the Left foot length
Diagnostic Efficacy of Troponin – I qualitative Rapid test in Sudden Cardiac Deaths
Authors: Kumar P P , Sabale P R , Amonkar G P
Published: September 2023

Everyone knows by conducting autopsy cause of sudden unexpected death can be established. However due to limitations of staff, budget and time it forces the autopsy surgeon to triage the cases. Out of which sudden cardiac deaths because of acute myocardial infarction constitute a significant percentage of caseload. When an autopsy is performed, there may be significant cardiovascular disease but there will be no gross or histological evidence of an acute myocardial infarct unless the patient survived for few hours. Troponin I (cTnI) done using peripheral blood was sampled percutaneously before conducting internal examination of each of 60 autopsies. The rapid assay result, histopathological results were tabulated and subsequently correlated. Out of 30 cases all showed positive result but in 30 controls 11 showed false positive results and 19 showed negative results. This result was statistically significant according to the chi-square test. The sensitivity of this assay in detecting cardiac-related death was 100%, with a specificity of 63.33%. In the appropriate setting, this rapid assay for cTnI can provide valuable data supportive of a cardiac-related death. This inexpensive test may best be used in triaging sudden deaths in persons and may optimize the use of the time and resources of the autopsy pathologist.
Pattern of Limb Injuries in Road Traffic Accident: A Cross-Sectional Study in a Tertiary Health Care Centre in North East India
Authors: Devi S E , Phanjoubam M , Angami A , Devi T M
Published: September 2023

According to World Health Organization, road traffic accident claims 1.2 million deaths annually and causes up to 50 million non-fatal injuries. Alimb injury is any injury to a limb, either a leg or arm, or to the toes and fingers. Limb injuries include broken bones (cracked or fractured bones, eg. a broken arm), dislocations (when a bone has been moved or dislodged, eg. a dislocated shoulder), sprains (injuries to ligaments, eg. a sprained ankle), strains (injuries to muscles, eg. a strained thigh), nail injuries (injuries to toenails and fingernails, eg., a stubbed toe), and bruises (colored marks caused by bleeding under the skin due to an impact). Across-sectional study was conducted in the mortuary of a tertiary health care centre in North-East India. The study was done from September 2019 to August 2021. All road traffic accident cases which were brought for medico legal autopsy were included. From the present study, it was found that maximum number of victims was due to two-wheeler accidents and most of the fatalities occurred after reaching hospital, mostly due to lack of prompt aid for the victim and less trauma center in the region. Injuries mostly seen are abrasion and a few cases of fracture. The cause of death is injury to major vessels involved in the fracture causing shock and hemorrhage. It is also observed that multiple limb injuries and limb injuries associated with fracture could be fatal which is significant (p< .001).
Pattern of Suicidal Deaths by Hanging at Tertiary Health Care Centre During COVID Pandemic
Authors: Kandade P S , Zanjad N P
Published: September 2023

COVID 19 pandemic continues to pose serious public health problems and also problems related to financial, social and psychological issues. Because of factors such as loneliness, stress, financial issues, many people committed suicide during pandemic. Hanging was the most common method adopted for committing suicide. The present study was conducted to highlight the current prevalence and pattern of suicidal deaths by hanging during COVID19 pandemic. We retrospectively reviewed suicidal deaths by hanging autopsied at tertiary medical care centre of Western Maharashtra st th during the period of 1 January 2021 to 30 June 2021. During the study period, 3780 medico-legal autopsies were performed, of which total 368 cases (9.73%) of death due to hanging were observed. Among 368 cases of death due to hanging, 366 (99.45%) were suicidal in nature while 02 cases (0.55%) were accidental in nature. Male outnumbered female with male: female ratio 3.46:1. The maximum number of cases (60.92%) was observed in age group of 21 to 40 years. The soft material was used in 190 cases (51.91%) while hard material was used in 176 cases (48.08%). The ligature material most commonly used for committing hanging was rope (46.17%) followed by saree (28.96%) and dupatta (17.75%). Most of victims 342 (93.44%) committed suicide by hanging in closed space like home and common close places.