bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN CUSTOMER SATISFACTION INDEX (CSI) DAN ANALISIS GAP PADA KUALITAS PELAYANAN KEFARMASIAN DI APOTEK NAROGONG BULAN APRIL 2022
Authors: Widiyanto Rahmat , Umul Angga Brahmono  , Bayu Dwi Handono  , Azelya Yoshe Martin
Published: December 2023

Pengukuran tingkat kepuasan pelanggan merupakan salah satu indikator yang digunakan untuk mengevaluasi kualitas pelayanan di apotek. Kualitas pelayanan apotek sangat berpengaruh terhadap kepuasan pelanggan. Kepuasan pelanggan yang belum tercapai, akan menjadi fokus penting bagi manajemen apotek untuk mengambil kebijakan dalam rangka memperbaiki kualitas pelayanan di apotek. Kepuasan pelanggan merupakan perasaan yang dimiliki pelanggan dan timbul sebagai hasil dari kinerja pelayanan setelah pelanggan membandingkannya dengan apa yang diharapkan. Adanya keluhan pelanggan Apotek Narogong menjadi indicator perlunya mengevaluasi kepuasan pelanggan. Tujuan penelitian ini adalah untuk mengetahui kepuasan dan harapan pelanggan terhadap kinerja pelayanan Apotek Narogong. Metode yang digunakan dalam penelitian ini adalah metode Customer Satisfaction Index (CSI) dan Analisis Gap. Penelitian ini dilakukan dengan metode survei, yaitu dengan yaitu membagikan kuesioner kepada pelanggan apotek. Pengambilan sampel menggunakan teknik purposive sampling. Jumlah sampel penelitian yang diambil adalah 184 responden. Skala yang digunakan adalah skala Likert yang berdasarkan tingkat kepuasan dan kepentingan Hasil penelitian menunjukkan bahwa nilai Customer Satisfaction Index (CSI) terhadap tingkat kepuasan pelanggan adalah sebesar 91,50% termasuk dalam kriteria sangat puas. Nilai gap tertinggi adalah indicator petugas apotek selalu memberikan informasi cara penggunaan obat yang diminta pelanggan dan nilai gap terendah adalah petugas apotek selalu murah senyum dan ramah.
UJI AKTIVITAS KOMBINASI KRIM EKSTRAK KULIT PISANG KEPOK (Musa paradisiaca L.) DAN KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) SEBAGAI PENYEMBUHAN LUKA BAKAR DERAJAT II PADA TIKUS PUTIH (Rattus norvegicus)
Authors: Wahyu Udayani Ni Nyoman , Febryna Dharma Yanti Ni Luh Putu , Arman Anita Dewi Ni Luh Kade
Published: December 2023

Luka bakar merupakan kerusakan jaringan kulit yang disebabkan oleh adanya panas. Kulit adalah organ terbesar pada permukaan tubuh dan melindungi jaringan yang ada dibawahnya. Pengobatan dengan menggunakan bahan herbal masih terus dilakukan guna meminimalisir efek samping obat. Kulit pisang kepok dan kulit buah naga merah merupakan salah satu bagian tanaman yang dapat menyembuhkan luka bakar karena memiliki senyawa flavonoid. Penelitian ini bertujuan untuk mengetahui aktivitas kombinasi krim ekstrak kulit buah pisang kepok dan kulit buah naga merah sebagai penyembuhan luka bakar derajat II pada tikus putih.

Penelitian ini bersifat eksperimental laboratorium. Pengujian menggunakan 20 ekor tikus yang dibagi menjadi 5 kelompok, semua tikus dibuatkan luka bakar dan diberikan pengobatan sehari sekali. Pengukuran diameter luas luka bakar dilakukan setiap tiga hari sekali selama 14 hari.

Hasil data pengukuran diuji secara statistik, menunjukan bahwa kombinasi krim ekstrak kulit pisang kepok dan kulit buah naga merah dengan persentase perbandingan yang berbeda yaitu F1 adalah 10%:7,5%, F2 adalah 15%:10%, dan F3 adalah 30%:15% memiliki aktivitas penyembuhan luka bakar. Berdasarkan hasil penelitian yang telah dilakukan kombinasi krim ekstrak kulit pisang kepok dan kulit buah naga merah dengan perbandingan 10%:7,5% sudah efektif dalam menyembuhkan luka bakar derajat II.
Anesthesia Approach for Nephrectomy in Full-Term Neonate with Suspected Wilms Tumor and Patent Foramen Ovale: A Case Report
Authors: Katarina Ida , Otniel Adrians Labobar  , I Putu Kurniyanta
Published: December 2023

Background: Nephrectomy for Wilms tumor presents a considerable challenge in pediatric anesthesia. This study aimed to describe the anesthesia approach for nephrectomy in a full-term neonate with suspected Wilms tumor and patent foramen ovale.

Case presentation: A 25-day-old male neonate was referred with a longstanding intraabdominal mass present since birth. Echocardiography revealed a patent foramen ovale with a diameter of 2.7 mm and a left-to-right shunt. The patient also had a diagnosis of partial ileus obstruction, likely caused by the tumor's pressure on the left kidney. Preoperative fasting adhered to a "6-4-3-1" regimen. Normoglycemia was maintained throughout the perioperative period. The case was managed under general anesthesia without the use of the rapid sequence induction technique. Caudal analgesia was administered using 1.14 ml of 0.175% bupivacaine. Vigilant monitoring of blood loss, prevention of hypothermia, and effective pain management are vital aspects of the surgical procedure. For postoperative pain management, analgesia and morphine infusion were employed. The patient was then transferred to the neonatal intensive care unit (NICU) for observation for any signs of complications related to anesthesia and surgery.

Conclusion: Nephrectomy in neonates is one of the challenges of pediatric anesthesia. Pre-anesthesia preparation in relation to hypertension control, analgesia plan and postoperative care site, transfusion strategy, and management of intravascular extension.
The Active Compound Content of Jamblang (Syzygium cumini) as an Anti-Breast Cancer
Authors: Mindawati Erisa , Depita Nurapni  , Siti Solihat  , Himyatul Hidayah
Published: December 2023

Jamblang is rich in bioactive compounds such as anthocyanins, phenolics, and flavonoids. Anthocyanins, which give jamblang fruit its dark color, have been known for their antioxidant properties that can fight oxidative stress, which is linked to the development of cancer. Phenolics, with their anti-inflammatory and antioxidant properties, provide additional protection to body cells. Flavonoids, with a wide range of biological activities, including anti-cancer properties, could potentially be promising agents in cancer prevention and treatment efforts. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of the active compound Jamblang (Syzygium cumini) as anti-breast cancer. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. The jamblang plant has potential as an anti-breast cancer agent. Jamblang plants are rich in active compounds that have anticancer activity, namely anthocyanins, flavonoids, phenolic compounds and carotenoids. These compounds can inhibit cancer cell growth, trigger apoptosis, and inhibit metastasis.
Biologic drugs, a new therapeutic paradigm in moderate-severe atopic dermatitis
Authors: Vignoli Carlo Alberto , Borroni Riccardo G.
Published: December 2023

Atopic dermatitis (AD), also referred to eczema, is a common inflammatory skin disease that usually presents during infancy or childhood but affects patients of all ages. It is a pruritic, chronic/relapsing condition that may significantly impact the patients’ quality of life and can be associated with other atopic comorbidities including asthma and rhinoconjunctivitis. Inflammation in AD is mostly sustained by type 2 inflammation. Most patients are satisfactorily managed with a combination of emollients, avoidance of triggering factors, topical glucocorticoids, and/or topical calcineurin inhibitors. However, a proportion of patients with moderate or severe AD might require phototherapy or systemic immunosuppressants, which are limited in time due to possible safety concerns and progressive efficacy loss. In recent years, the availability of T helper 2 (Th2)-blocking agents dupilumab and tralokinumab has revolutionized the long-term treatment of moderate-to-severe AD. Here are discussed recent advances in the clinical development of biologic treatments for AD. The clinical implementation of these novel drugs has the potential not only to greatly improve the quality of life of patients with this chronic and disabling condition but also to clarify the biological processes underlying AD, in turn enabling further development of more effective, safer treatments. This research paper aims to provide an overview of biological therapies currently in use and under investigation in the setting of AD.
Analisis Kepuasan Pengguna Aplikasi DANA Menggunakan Metode TAM dan EUCS
Authors: Fitratul Aini  , Fitriani Muttakin  , Tengku Khairil Ahsyar  , Eki Saputra
Published: December 2023

The DANA application is a payment system service that can be used via a smartphone, which can be in the form of fund transfers, electronic wallets, electronic money and other supporting services. User satisfaction with the application is very important, because it can be used as an assessment material for improving the service quality of the application. By combining two methods, namely the Technology Acceptance Model (TAM) which contains the variables Perceived Usefulness, Perceived Ease of Use and Attitude Toward Using and End User Computing Satisfaction (EUCS) which contains the variables Content, Accuracy, Format, Ease of Use and Timeliness to measure application user satisfaction DANA is the aim of this research. The technique that will be used to collect data is by distributing questionnaires to DANA application users. Through lameshow calculations, there were 100 respondents in this study. Based on the results of the analysis carried out, there are 6 hypotheses that are accepted, namely Perceived Usefulness, Content, Accuracy, Format, Ease of Use and Attitude Toward Using and 2 hypotheses are rejected, namely Perceived Ease of Use and Timeliness. The results obtained through SEM analysis are classified as good with an R-Square correlation value of 75.2% for user satisfaction variables.
Frailty in end-stage liver disease: Understanding pathophysiology, tools for assessment, and strategies for management
Authors: Elsheikh Mazen , Sabagh Ahmed El , Mohamed Islam B , Bhongade Megha , Hassan Manal M , Jalal Prasun Kumar
Published: December 2023

Frailty and sarcopenia are frequently observed in patients with end-stage liver disease. Frailty is a complex condition that arises from deteriorations across various physiological systems, including the musculoskeletal, cardiovascular, and immune systems, resulting in a reduced ability of the body to withstand stressors. This condition is associated with declined resilience and increased vulnerability to negative outcomes, including disability, hospitalization, and mortality. In cirrhotic patients, frailty is influenced by multiple factors, such as hyperammonemia, hormonal imbalance, malnutrition, ascites, hepatic encephalopathy, and alcohol intake. Assessing frailty is crucial in predicting morbidity and mortality in cirrhotic patients. It can aid in making critical decisions regarding patients’ eligibility for critical care and transplantation. This, in turn, can guide the development of an individualized treatment plan for each patient with cirrhosis, with a focus on prioritizing exercise, proper nutrition, and appropriate treatment of hepatic complications as the primary lines of treatment. In this review, we aim to explore the topic of frailty in liver diseases, with a particular emphasis on pathophysiology, clinical assessment, and discuss strategies for preventing frailty through effective treatment of hepatic complications. Furthermore, we explore novel assessment and management strategies that have emerged in recent years, including the use of wearable technology and telemedicine.
Evaluasi Konstruktivisme Sosial Sebagai Pendekatan Pendidikan Karakter di Era Digital
Authors: Hafizi Zainul
Published: December 2023

This study aims to evaluate the effectiveness of social constructivism approach in shaping student character in the digital era. In the context of the development of information and communication technology, the challenges faced in character education are increasingly complex. Therefore, this study uses the literature review method to analyze related theories, evaluate the impact of the digital era on character formation, and develop a social constructivism model that is suitable for character education in the digital era. The results showed that social constructivism, which emphasizes the role of social interaction, collaboration, and shared learning, has great potential in shaping students' positive character. The social constructivism approach model developed in this study integrates technology as an aid in character learning. Teaching strategies that focus on collaboration, social interaction, and project-based learning encourage students to develop social skills, empathy, and emotional intelligence. Evaluation of the implementation of this model shows improvement in the development of student character. They are able to collaborate better, have a deeper understanding of character values, and can live social interactions positively in the challenging digital age. Recommendations include teacher training in integrating technology in character education, development of appropriate digital learning resources, and parental involvement in supporting character education at home. Support from schools and relevant stakeholders is also considered important in creating an educational environment that supports student character development in the digital era. This research provides an in-depth look at the role of social constructivism and technology in shaping student character in the ever-evolving digital age.
Determinants of gini ratio: a case study of low gini ratio in Madura
Authors: Mahdi Imam , Sulistyono Setyo Wahyu
Published: December 2023

One of the regencies on Madura Island, namely Sumenep, will be the regency with the lowest gini ratio in East Java Province in 2022. This research was conducted to analyze: 1) the effects of health, education, open unemployment rate, and poverty rate partially on the Gini ratio; 2) the effects of health, education, open unemployment rate, and poverty rate simultaneously on the Gini ratio in Madura Island. The research method was carried out using panel data regression. The results obtained using the CEM: 1) health, education, and poverty levels have a negative and not significant effect; 2) the open unemployment rate influences positively and significantly; 3) all independent variables simultaneously have a significant positive effect. The government can issue policies to reduce income inequality in the form of providing free health services, education and compulsory education scholarships, periodic job fairs, skills training for workers, and distribution of social assistance that is right on target.
Pengaruh invesment opportunity set (IOS), kepemilikan manajerial, dan kepemilikan institusional terhadap kualitas laba
Authors: Tinenti Rasy Vania Jurike , Nugrahanti Yeterina Widi
Published: December 2023

Tujuan penelitian adalah menguji pengaruh investment opportunity set, kepemilikan manajerial dan kepemilikan institusional pada kualitas laba. Perusahaan LQ45 yang listing di Bursa Efek Indonesia periode 2019 – 2021 menjadi populasi dalam penelitian ini. Sampel ditentukan menggunakan teknik purposive sampling, sehingga diperoleh 25 perusahaan selama periode penelitian. Jenis penelitian ini adalah kuantitatif dengan sumber data sekunder. Teknik analisis yang digunakan adalah analisis regresi data panel. Data diolah pada program eviews versi 12. Hasil penelitian menunjukkan bahwa IOS berpengaruh positif signifikan terhadap kualitas laba pada perusahaan LQ45. Kepemilikan manajerial dan kepemilikan institusional tidak berpengaruh secara signifikan terhadap kualitas laba pada perusahaan LQ45. Variabel kontrol return on assets (ROA) berpengaruh positif signifikan terhadap kualitas laba pada perusahaan LQ45. Variabel kontrol ukuran perusahaan berpengaruh negatif signifikan terhadap kualitas laba pada perusahaan LQ45.
Dinamika harga dan volume perdagangan saham bank digital Indonesia: sebuah pendekatan VECM
Authors: Ary William Wendy
Published: December 2023

Perkembangan teknologi telah memengaruhi transformasi bisnis digital dan hal ini ditandai dengan kemunculan beberapa perbankan digital dan perusahaan fintech. Selanjutnya, beberapa literatur berkaitan dengan perbankan digital telah menelaah peranan transformasi digital terhadap inovasi dalam perbankan dan sedikit sekali yang meneliti mengenai dinamika harga dan volume perdagangan saham perbankan digital. Penelitian ini menggunakan VECM untuk mengeksplorasi dinamika tujuh saham perbankan Indonesia dan 495 data harga dan volume perdagangan digunakan dan beberapa pengujian awal dilakukan untuk memastikan validitas pengukuran data. Hasil penelitian menunjukkan bahwa harga saham perbankan digital dipengaruhi oleh harga saham perbankan digital itu sendiri dan hal itu juga telihat pada volume perdagangan saham. Selanjutnya, hasil penelitian juha menunjukkan bahwa ARTO, BABP, dan BBHI mempengaruhi harga dan volume perdagangan saham perbangan digital Indonesia. Akhirnya, beberapa rekomendasi terkait penelitian selanjutnya disajikan dalam penelitian ini.
Contusion Spinе Injury in the Thoracolumbar Junction Region
Authors: Nekhlopochyn O.S. , Verbov V.V. , Tsymbaliuk Ia. V. , Cheshuk Ie. V. , Vorodi M.V.
Published: December 2023

Summary – Contusion spine injuries resulting from direct traumatic mechanisms that lead to spinal cord lesion are relatively rare during peacetime. The specific characteristics of such injuries are not extensively covered in contemporary literature. The need to optimize treatment methods for military personnel engaged in active combat operations on the territory of Ukraine necessitates an examination of this specific type of injury.

Objective: To describe the clinical presentation and explore possible therapeutic approaches for closed contusion spinal cord injuries in the thoracolumbar junction.

Materials and Methods: We conducted an analysis of patient data from those admitted for inpatient treatment at the Romodanov Neurosurgery Neurosurgery of National Academy of Medical Sciences of Ukraine, as well as patients referred to other healthcare institutions in Kyiv, from February 2022 to May 2023.

Results: We analyzed the treatment outcomes of 5 patients, aged 27 to 53 years (mean age: 37.6 years), presenting with initial neurological deficits classified as ASIA A. Surgery was performed in 3 patients. All cases underwent wide laminectomy with facetectomy at the level of injury. Large arachnoid cysts were drained, and in one case, a subdural hematoma was removed. Posterior spinal fusion using an 8-screw transpedicular system was performed in all patients, utilizing a minimally invasive percutaneous approach. At the 2-month follow- up positive dynamics were observed in all patients. Neurological status improved to ASIA B in 2 cases and ASIA C in 1. Recovery of proprioceptive sensitivity was noted, as well as an increase in the intensity of neuropathic pain (up to 5-7 points at 2 months). In 2 patients undergoing conservative therapy, the neurological impairment level remained ASIA A, with pain intensity not exceeding 2 points.

Conclusions: The findings emphasize the need for more comprehensive instrumental assessment in patients with suspected contusion spinal cord injuries. Active use of surgical treatment methods in this type of injury contributes to achieving better clinical outcomes.
Bearing Fault Diagnosis Based on Graph Formulation and Graph Convolutional Network
Authors: Wang Xin , Zhou Wenjin , Li Xiaodong
Published: December 2023

Bearing fault diagnosis stands as a critical component in the maintenance of rotating machinery. Many prevalent deep learning techniques are tailored to Euclidean datasets such as audio, image, and video. However, these methods falter when confronting non-Euclidean datasets, notably graph representations. In response, here we introduce an innovative approach harnessing the Graph Convolutional Network (GCN) to analyze graph data derived from vibration signals related to bearing faults. This enhances the precision and reliability of fault diagnosis. Our methodology initiates by deriving a periodogram from the unprocessed vibration signals. Subsequently, this periodogram is mapped into a graph format, upon which the GCN is engaged for classification purposes. We substantiate the efficacy of our approach through rigorous experimental assessments conducted on a collection of ten bearing sets. Within these experiments, an accelerometer chronicles vibration signals across varying load conditions. We probe into the diagnostic accuracy rates across diverse loads and Signal-to-Noise Ratios (SNRs). Furthermore, a comparative evaluation of our method against several established algorithms delineated in this study is undertaken. Empirical observations confirm that our GCN-based strategy registers an elevated diagnostic accuracy quotient.
Gender Equality or Inequality in Learning Institutions in South Africa: A Case of the Professional Advancement of Women
Authors: Khosa Dee
Published: December 2023

This study unveils the role of gender issues in the professional advancement of women in learning institutions. The study investigated the status of women’s professional advancement in South African learning institutions and identified the obstacles encountered by women in advancing professionally in these institutions. The study examined the work environment in learning institutions when women are in leadership positions and discussed male employees’ perceptions of female colleagues and superiors. The research used a primary data-gathering technique and a qualitative data-collection tool in a descriptive research strategy under the interpretivist research philosophy. The study’s target population included both women and men in learning institutions in South Africa. The participants were chosen for interviews using the purposive sampling technique. Following the thematic analysis approach, the findings revealed that there are several opportunities for women to progress in their careers at South African educational institutions, as well as several leadership roles. They are also given increased trust and responsibility. Some participants believed that there are no barriers that prevent women from advancing professionally in educational institutions whereas others believed that existing barriers are primarily caused by individual issues, a lack of support, cultural issues, and concerns about sexual misconduct. When women are in positions of leadership, the perception of the workplace atmosphere is equivocal. While certain participants felt that jealousy made the workplace hostile, others believed that the environment was inviting and provided opportunities for female employees to advance. Finally, it was indicated that the paradigm for empowering women in South Africa must emphasise seizing chances, providing a guiding structure, recognising efforts and successes, and eliminating patriarchy. This study contributes to the existing discourse on the role of gender in the career advancement of women.

Keywords: Gender Equality, Inequality, Learning Institutions, Women’s Professional Advancement, Gender Roles
Study of the Blazhko Type RRc stars in the Stripe 82 Region Using SDSS and ZTF
Authors: Varma Vaidehi , Benkő József M. , Ngeow Chow-Choong
Published: December 2023

RR Lyrae stars (RRLs) are pulsating stars, many of which also show a long-term variation called the Blazhko effect which is a modulation of amplitude and phase of the lightcurve. In this work, we searched for the incidence rate of the Blazhko effect in the first-overtone pulsating RR Lyrae (RRc) stars of the Galactic halo. The focus was on the Stripe 82 region in the Galactic halo which was studied by Sesar et al. using the Sloan Digital Sky Survey (SDSS) data. In their work, 104 RRLs were classified as RRc type. We combined their SDSS light curves with Zwicky Transient Facility (ZTF) data, and used them to document the Blazhko properties of these RRc stars. Our analysis showed that among the 104 RRc stars, eight were rather RRd stars, and were excluded from the study. Out of the remaining 96, 34 were Blazhko type, 62 were non-Blazhko type, giving the incidence rate of 35.42% for Blazhko RRc stars. The shortest Blazhko period found was 12.808 ± 0.001 days for SDSS 747380, while the longest was 3088 ± 126 days for SDSS 3585856. Combining SDSS and ZTF data sets increased the probability of detecting the small variations due to the Blazhko effect, and thus provided a unique opportunity to find longer Blazhko periods. We found that 85% of RRc stars had the Blazhko period longer than 200 days.
The First Y Dwarf Data from JWST Show that Dynamic and Diabatic Processes Regulate Cold Brown Dwarf Atmospheres
Authors: Leggett S. K. , Tremblin Pascal
Published: December 2023

The James Webb Space Telescope (JWST) is now observing Y dwarfs, the coldest known brown dwarfs, with effective temperatures T
eff ≲ 475 K. The first published observations provide important information: not only is the atmospheric chemistry out of equilibrium, as previously known, but the pressure–temperature profile is not in the standard adiabatic form. The rapid rotation of these Jupiter-size, isolated, brown dwarfs dominates the atmospheric dynamics, and thermal and compositional changes disrupt convection. These processes produce a colder lower atmosphere, and a warmer upper atmosphere, compared to a standard adiabatic profile. Leggett et al. presented empirical models where the pressure–temperature profile was adjusted so that synthetic spectra reproduced the 1 ≲ λ (μm) ≲ 20 spectral energy distributions of brown dwarfs with 260 ≤ T
eff (K) ≤ 540. We show that spectra generated by these models fit the first JWST Y dwarf spectrum better than standard-adiabat models. Unexpectedly, there is no 4.3 μm PH3 feature in the JWST spectrum and atmospheres without phosphorus better reproduce the 4 μm flux peak. Our analysis of new JWST photometry indicates that the recently discovered faint secondary of the WISE J033605.05-014350AB system has T
eff ≈ 295 K, making it the first dwarf in the significant luminosity gap between the 260 K WISE J085510.83-071442.5, and all other known Y dwarfs. The adiabat-adjusted disequilibrium-chemistry models are recommended for analyses of all brown dwarfs cooler than 600 K, and a grid is publicly available. Photometric color transformations are provided in an appendix.
Little Ado about Everything: ηCDM, a Cosmological Model with Fluctuation-driven Acceleration at Late Times
Authors: Lapi Andrea , Boco Lumen , Cueli Marcos M. , Haridasu Balakrishna S. , Ronconi Tommaso , Baccigalupi Carlo , Danese Luigi
Published: December 2023

We propose a model of the Universe (dubbed ηCDM) featuring a controlled stochastic evolution of the cosmological quantities that is meant to render the effects of small deviations from homogeneity/isotropy on scales of 30–50 h
−1 Mpc at late cosmic times associated with the emergence of the cosmic web. Specifically, we prescribe that the behavior of the matter/radiation energy densities in different patches of the Universe with such a size can be effectively described by a stochastic version of the mass–energy evolution equation. The latter includes, besides the usual dilution due to cosmic expansion, an appropriate noise term that statistically accounts for local fluctuations due to inhomogeneities, anisotropic stresses, and matter flows induced by complex gravitational processes. The evolution of the different patches as a function of cosmic time is rendered via the diverse realizations of the noise term; meanwhile, at any given cosmic time, sampling the ensemble of patches will create a nontrivial spatial distribution of the various cosmological quantities. Finally, the overall behavior of the Universe will be obtained by averaging over the patch ensemble. We assume a simple and physically reasonable parameterization of the noise term, gauging it against a wealth of cosmological data sets in the local and high-redshift Universe. We find that, with respect to standard ΛCDM, the ensemble-averaged cosmic dynamics in the ηCDM model is substantially altered by the stochasticity in three main respects: (i) an accelerated expansion is enforced at late cosmic times without the need for any additional exotic component (e.g., dark energy), (ii) the spatial curvature can stay small even in a low-density Universe constituted solely by matter and radiation, (iii) matter can acquire an effective negative pressure at late times. The ηCDM model is Hubble tension–free, meaning that the estimates of the Hubble constant from early- and late-time measurements do not show marked disagreement as in ΛCDM. We also provide specific predictions for the variance of the cosmological quantities among the different patches of the Universe at late cosmic times. Finally, the fate of the Universe in the ηCDM model is investigated to show that the cosmic coincidence problem is relieved without invoking the anthropic principle.
ALMA Millimeter/Submillimeter Sources among Spitzer SMUVS Galaxies at z > 2 in the COSMOS Field
Authors: Suzuki Tomoko L. , van Mierlo Sophie E. , Caputi Karina I.
Published: December 2023

Submillimeter observations reveal the star formation activity obscured by dust in the young Universe. It still remains unclear how galaxies detected at submillimeter wavelengths are related to ultraviolet/optical-selected galaxies in terms of their observed quantities, physical properties, and evolutionary stages. Deep near- and mid-infrared observational data are crucial to characterize the stellar properties of galaxies detected with submillimeter emission. In this study, we make use of a galaxy catalog from the Spitzer Matching survey of the UltraVISTA ultra-deep Stripes. By crossmatching with a submillimeter source catalog constructed with archival data of the Atacama Large Millimeter/submillimeter Array (ALMA), we search for galaxies at z > 2 with a submillimeter detection in our galaxy catalog. We find that the ALMA-detected galaxies at z > 2 are systematically massive and have redder K

s
–[4.5] colors than the nondetected galaxies. The redder colors are consistent with the larger dust reddening values of the ALMA-detected galaxies obtained from spectral energy distribution (SED) fitting. We also find that the ALMA-detected galaxies tend to have brighter 4.5 μm magnitudes. This may suggest that they tend to have smaller mass-to-light ratios and thus to be younger than star-forming galaxies fainter at submillimeter wavelengths with similar stellar masses. We identify starburst galaxies with high specific star formation rates among both ALMA-detected and nondetected SMUVS sources. Irrespective of their brightness at submillimeter wavelengths, these populations have similar dust reddening values, which may suggest a variety of dust SED shapes among the starburst galaxies at z > 2.
Nonthermal Atmospheric Escape on the Kepler-11 “Super-Earths” Driven by Stellar Wind Sputtering
Authors: Gu Hao , Wu Xiaoshu , Huang Xu , Guo Jianheng , Cui Jun
Published: December 2023

Jeans escape or hydrodynamic escape is believed to dominate atmospheric loss for hot Jupiters. However, nonthermal mechanisms likely contribute substantially on hydrogen-rich “super-Earths” with relatively cold and extended atmospheres. This study is devoted to investigating the role of stellar wind sputtering on Kepler-11b–f, with the aid of Monte Carlo test particle calculations. Such a mechanism is widely known to be important on many solar system bodies, but its impact has never been evaluated rigorously on any exoplanet. Our calculations reveal complicated variations of the H sputtering yield with the stellar wind inclination angle and neutral heating efficiency at different Kepler-11 planets. Further calculations suggest the H loss rates on Kepler-11b–f to be 2.8 × 106–1.5 × 108 g s−1, driven by stellar wind sputtering. The H loss rate obtained here is compared to those driven by other mechanisms, indicating that the importance of stellar wind sputtering is highly variable and this mechanism could induce a large atmospheric loss rate comparable to the blow-off rate driven by stellar far-ultraviolet radiation, in particular for planets with relatively low gravities.
Ochrobactrum intermedium septicemia
Authors: Subramanian Pramodhini , Bhosale Namrata K , Easow Joshy M , Chandramouli Chandni , Chenthil K S
Published: December 2023

Ochrobactrum species are emerging Gram-negative, non-fermenting bacteria with low virulence. Infection with the Ochrobactrum species is commonly nosocomial and has been reported in patients with indwelling medical devices and implants. Among the species of Ochrobactrum infecting humans, Ochrobactrum anthropic and Ochrobactrum intermedium are the commonest ones. We present a case of septicemia caused by Ochrobactrum intermedium in a 75-year-old patient with lower limb cellulitis. This report describes the epidemiology, clinical manifestations, laboratory diagnosis, antibiotic susceptibility pattern, and treatment of Ochrobactrum infections.
Clinical and pathological factors associated with Ehrlichia canis in companion dogs
Authors: Espino-Solís Gerardo Pavel , Flores-Lira Erika Astrid , Barreras-Serrano Alberto , García-Reynoso Issa Carolina , De la Mora Covarrubias Antonio , Jiménez Vega Florinda , Escárcega-Ávila Angélica
Published: December 2023

Introduction: Canine monocytic ehrlichiosis (CME) is a disease caused by the Gram-negative bacteria Ehrlichia canis, a bacterium that affects domestic dogs but can also infect humans. The diagnosis implies a challenge due to its diversity in clinical manifestations.
Methodology: The frequency of E. canis infection, risk factors, and clinical-pathological parameters associated with seropositivity were calculated with the PROC FREQ TABLES and PROC LOGISTIC procedures of the SAS statistical software.
Results: The study showed a seroprevalence of 26.62% (156/586). Association between seropositivity and risk factors was found. The age and the presence of ticks including clinical signs such as anorexia, seizures, cough, petechiae, epistaxis, and hematochezia, as well as multiple blood and biochemical alterations were analyzed. The logistic regression analysis showed a high predictive power (c = 0.98) for CME for thrombocytopenia, leukopenia, and anemia.
Conclusions: The high prevalence of E. canis in endemic areas makes its diagnosis difficult. Thus, clinical signs must be considered, along with blood and biochemical alterations, as a possible predictor of the disease.
A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient
Authors: Tomanovic Marija , Reljic Vesna , Peric Jelena , Zivanovic Dubravka
Published: December 2023

Introduction: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris.
Case presentation: The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins.
Conclusions: Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place.
New data on trophic associations of dung beetles (Coleoptera, Scarabaeidae, Scarabaeinae) and lemurs (Primates, Lemuroidea) in Madagascar
Authors: Frolov Andrey , Vishnevskaya Maria , Viljanen Heidi , Montreuil Olivier , Akhmetova Lilia
Published: December 2023

Resource use and diet specialization of Madagascan dung beetles has been little studied especially concerning the possible associations between specific dung beetle and lemur species. Pilot studies have demonstrated that amplicon metagenomics is a promising tool for the lemur inventories. In the present contribution, we report new results of the gut content analysis of three endemic Madagascan dung beetles species: Helictopleurus clouei (Harold), Epilissus apotolamproides (Lebis) and Nanos dubitatus (Lebis). Amplicon metagenomics revealed trophic associations of these species with Eulemur sanfordi (Archbold), Eu. fulvus (É.Geoffroy Saint-Hilaire), and Cheirogaleus crossleyi (Grandidier), respectively. The reads of other mammal species, revealed by the analysis, including putative contaminations, are discussed.
Research collaboration between global North and global South assessed in terms of published output: a case study of Australia and Vietnam
Authors: Pham Hiep-Hung , Phan Thanh Thao , Do Minh-Trang , Luong Dinh-Hai
Published: December 2023

Background: Vietnam and Australia have a long-standing history of collaboration in various fields, notably education, science, and technology. However, the results of this partnership remain indeterminate.

Objectives: The aim of this study was to examine the current state of research coop-eration between Australia and Vietnam with reference to the following aspects: (1) increase in the number of research publications over time; (2) proportion of open access (OA) publications in total publications; (3) collaboration involving countries other than Australia and Vietnam; (4) funding sources; (5) top institutions; (6) subject areas; and (7) research topics.

Methods: Scopus data set was analysed to identify those papers with two or more authors, with at least one author from Australia and at least one from Vietnam.

Results: Most (nearly 84%) of research papers arising out of such collaborative research were published between 2014 and 2022 (7020 of the total of 8460 documents), and almost half (49.6%) of those are OA. Besides Australia and Vietnam, the authors of those papers were from other countries as well nor were the agencies that funded the research reported in those papers limited to Australia or Vietnam. Among the countries involved in terms of co-authorship or funding, the United States was the most influential. The institutional collaborations formed three distinct clusters, each with a varying number of members and a different university at the core (Australian in two clusters and Vietnamese in the third). Medicine was the most frequent field of collaborative research, and the most frequent topics were Vietnam, coronavirus disease 2019, and climate change.

Conclusions: The findings offer useful insights to policymakers as well as to senior management of academic institutes in Vietnam and Australia. The study also extends our understanding of collaborative research between the Global North and the Global South.
Cough in Severe Asthma
Authors: Lee Hwa Young , Lee Young Jae , Song Woo-Jung
Published: December 2023

Asthma is a heterogeneous clinical syndrome that presents with variable symptoms, including cough, breathlessness, chest discomfort, and wheezing. Cough, a primary symptom of asthma, has distinct regulatory mechanisms and was associated with asthma severity, poor asthma control, diminished quality of life, and an increased risk of frequent future exacerbations. However, current tools for measuring asthma control do not include separate items for cough or other specific symptoms, and the true impact and clinical relevance of cough in asthma remains poorly understood. Consequently, current stepwise treatment algorithms based on asthma control may be overly simplistic and might not adequately address the heterogeneity of asthma or the mechanisms underlying its symptoms. Furthermore, this approach carries the risk of overestimating asthma severity and subsequent overtreatment. The concept of treatable traits is fundamental to precision medicine, wherein each symptom, especially cough, may serve as a treatable trait in its own right. In this paper, we aim to present evidence supporting the concept of cough as a treatable trait in asthma, addressing its three major components, which are clinical relevance, measurability, and treatability.
Les « petites phrases » : un objet pour l’analyse des discours politiques et médiatiques
Authors: Krieg-Planque Alice
Published: December 2023

Résumé Ce texte s’emploie à caractériser les « petites phrases » en tant qu’objet pour l’analyse des discours politiques et médiatiques, dans le cadre plus large d’une étude des faits de communication dans leur dimension discursive. Les « petites phrases » sont appréhendées sous plusieurs aspects, dont les termes sont explicités : caractéristiques de l’expression « petite phrase » elle-même ; dimension énonciative du phénomène ; déterminants génériques et sémiotiques façonnés par les médias ; intégration des contraintes par les politiques et les communicants ; caractéristiques qui favorisent la reprise et la circulation des énoncés ; appréciation par les acteurs sociaux eux-mêmes du phénomène des « petites phrases ».
Sport et presse quotidienne régionale : un journalisme sous influence ?
Authors: Parrot Benjamin , Patrin-Leclère Valérie
Published: December 2023

Résumé Cet article permet de bien cerner et de mieux comprendre les tâtonnements qui caractérisent les pratiques des journalistes, alors que la profession apparaît souvent comme une corporation guidée par des règles et des lignes éditoriales précises. Il est écrit par un journaliste sportif qui témoigne de sa vie professionnelle, dans un club puis dans un titre de presse locale. Il est mis en perspective par une chercheuse qui travaille sur les transformations des médias et du journalisme. Avec recul et sincérité, l’auteur raconte ce à quoi nul observateur extérieur n’a d’ordinaire accès : la pratique ordinaire du journalisme.
Le djihad sahélien à l’épreuve de l’Histoire
Authors: Pérouse de Montclos Marc-Antoine
Published: December 2023

Le djihadisme au Sahel est-il simplement un « produit d’importation », étranger à l’islam africain ? L’histoire de la région invite à nuancer cette représentation. Le développement d’États laïcs après l’Indépendance a tendu à occulter l’existence de forces religieuses actives dans le champ politique.
Jusqu’où assister médicalement la procréation ?
Authors: Saintôt Bruno
Published: December 2023

Jusqu’où assister médicalement la procréation ? Deux avis du Comité consultatif national d’éthique (CCNE) ont cherché à répondre à cette question dans des contextes différents, en 2005 et en 2017. Ils sont en contradiction sur des points essentiels. De plus, le dernier avis présente bien des paradoxes et des tensions non résolues. Il importe donc de les mettre au jour, afin de poursuivre les débats.
Un burn-out propre aux chrétiens
Authors: Gueullette Jean-Marie
Published: December 2023

La survenue d’un syndrome d’épuisement professionnel est, de l’avis de tous les chercheurs, imputable à une pluralité de facteurs, les causes de ce burn-out pouvant être identifiées aussi bien chez le sujet que dans le fonctionnement de l’organisation. Le christianisme doit-il être regardé comme un facteur aggravant du burn-out ? Peut-on au contraire puiser dans cette tradition spirituelle des éléments de sens qui puissent servir de garde-fou contre l’écroulement ?
La mission chrétienne en modernité liquide
Authors: Join-Lambert Arnaud
Published: December 2023

Dans une société « liquide », l’annonce de l’Évangile prend des formes diverses. Les modèles récents (postconciliaires) ne sont pas nécessairement caducs. Le pape François semble proposer sa propre manière d’envisager la mission de l’Église. Ces différents modèles sont-ils incompatibles ? À quelles conditions pourraient-ils être complémentaires ?
L’édition du génome
Authors: Morange Michel
Published: December 2023

Une nouvelle technique de modification génétique, appelée « CRISPR-Cas9 », a beaucoup fait parler d’elle. Comment a-t-elle été découverte ? Quelles sont ses applications possibles ? Quelles questions éthiques cette technique soulève-t-elle ?
Simone Veil
Authors: Veil Aurélien , Sarthou-Lajus Nathalie
Published: December 2023

Au cours d’un entretien, Aurélien Veil revient sur quelques-uns des héritages laissés par sa grand-mère : la mémoire de la Shoah, son combat pour la liberté des femmes, ses convictions européennes... Peu à peu, il dresse le portrait d’une femme hors du commun, dont les engagements publics ont marqué notre destin national.
Léon Bloy
Authors: Godo Emmanuel
Published: December 2023

L’invention verbale, les audaces inouïes du style de Léon Bloy, son sens de la formule choc ne sauraient être réduits, comme le fait une culture littéraire parfois paresseuse, à un art de la saillie et du bon mot. Bloy prend au col les tiédeurs morales de son temps, et fait éprouver au lecteur les démissions spirituelles dont celui-ci se contente. L’éloquence du pauvre est tout sauf une pauvre éloquence : elle prend au pied de la lettre le Texte sacré et s’indigne de tout ce qui vient entraver l’avènement de la Promesse.
La France et les chrétiens d’Orient
Authors: Peaucelle Jean-Christophe
Published: December 2023

L’actualité récente a attiré l’attention sur la situation des communautés chrétiennes du Proche-Orient. Pour des raisons historiques, la France entretient une relation particulière avec ces communautés. Cela lui donne une responsabilité et l’invite à prendre des initiatives.
Le succès du télétravail
Authors: Ollivier Daniel
Published: December 2023

Depuis quelques années, le télétravail connaît en France un développement considérable et cette dynamique va se poursuivre, puisque la moitié des emplois seront « télétravaillables » à l’horizon de 2030. Daniel Ollivier explique les raisons d’un tel succès, les résultats obtenus mais aussi les questions que soulèvent les ordonnances de la nouvelle loi Travail.
Figure actuelle de l’agnostique
Authors: Riquier Camille
Published: December 2023

La figure de l’agnostique, jadis isolée, a fini par prendre la plus grande part, jusqu’à estomper quelque peu la frontière qui séparait les athées et les croyants. Après avoir esquissé une histoire de l’agnosticisme, l’auteur s’appuie sur deux exemples, le romancier Emmanuel Carrère, figure de l’agnostique athée, et le philosophe Gianni Vattimo, figure de l’agnostique chrétien.
Le fait religieux en entreprise, un fait social total
Authors: Gherardi Sophie
Published: December 2023

La diversité est vécue, voire célébrée, dans le monde de l’entreprise. Mais, dès qu’il s’agit de religion, les situations sont contrastées. Il n’est pas facile de faire fonctionner ensemble le refus de toute discrimination et le minimum de neutralité qui permet le bon fonctionnement de l’entreprise. Nous assistons aujourd’hui à l’extension du champ de la laïcité.
Dominique Rolin, toujours
Authors: Sollers Philippe , Boyer de Latour Patricia
Published: December 2023

Après une traversée de plus de « cinquante ans d’amour fou », le duo Sollers-Rolin est entré dans la légende littéraire. Ces deux amants sont d’abord et avant tout deux écrivains. Au fil de sa correspondance 1 avec cette femme de plus de vingt ans son aînée, qu’il ne cessera jamais d’aimer, Philippe Sollers 2 dévoile des facettes méconnues de sa vie qui l’ont entièrement façonné, corps et âme.
Les mots du numérique à l’école
Authors: Serrano Gemma
Published: December 2023

Les questions que pose le vocabulaire du numérique témoignent de la difficulté à saisir, de manière claire et univoque, les transformations qu’il produit. Cette interrogation est nécessaire pour comprendre comment l’école pourra former les jeunes à habiter dans ce nouvel environnement avec un esprit critique et de manière libre. Par ailleurs, l’entrée de l’école dans « l’âge numérique » interroge directement sa finalité : est-elle un sanctuaire, une agora, un marché ? À quelles exigences éducatives répond-elle ?
Une éducation cartésienne
Authors: Devillairs Laurence
Published: December 2023

Descartes est avant tout un réformateur. L’éducation à la liberté de penser qu’il propose commence par le doute. Mais il ne tourne pas simplement le dos aux traditions et aux maîtres, dans un geste d’émancipation. Il vise, dans une soif de vérité, à nous affranchir des préjugés et de notre tempérament de suiveur par le biais de la méditation. Descartes est l’inventeur de la méditation en philosophie.