bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of GastrointestinalEndoparasites in Native Chickens (Gallus domesticus)in PattongkoVillage, Sinjai Tengah District, Sinjai Regency
Authors: Evi Erviani Andi , Hasyim Zohra , Musawwir Saeful
Published: January 2025

One of the livestock commodities in South Sulawesi is local chicken or native chicken (Gallus domesticus). Although this type of chicken has a high adaptability ability, native chickens can also experience illness and population reduction on farms that can be caused by worm-type endoparasites. This study was conducted from July to August 2023 in Pattongko Village, Central Sinjai District, Sinjai Regency with the aim of finding out what types of endoparasites are found in the gastrointestinal of native chickens in Pattongko Village. Sampling was carried out by random sampling method using 20 native chickens whose feces were taken as much as 5 grams per head. Sample preparation was carried out at the Zoology Laboratory FMIPA Hasanuddin University and sample examination and identification were carried out at the Parasitology Laboratory of the Maros Veterinary Center, which conducts 3 types of sample testing, namely the native method, the flotation method and the sedimentation method. The results of the study found 5 species of gastrointestinal endoparasites belonging to 2 classes, namely the nematode and cestode classes. Parasitic worms belonging to the nematode class are Heterakis spp., Ascaridia spp., Syngamus spp. and Capillaria spp. While parasitic worms belonging to the cestode class are Hymenolepis spp.
Analisa Kelayakan Instalasi Listrik Bangunan Yang Berusia Diatas 15 Tahun Di Kabupaten Aceh Besar
Authors: Khudzari Ahmad , Lastya Hari Anna , Mursyidin Mursyidin
Published: January 2025

Sistem instalasi merupakan suatu hal yang sangat penting bagi sebuah bangunan. Semua instalasi listrik, termasuk keselamatan, perlindungan, dan peralatan, harus selalu diperbarui terutama pada bangunan yang berusia lebih tua. Penelitian bertujuan untuk mengetahui standar kelayakan yang ada pada bangunan tua di wilayah kabupaten Aceh Besar. Metode penelitian yang digunakan pada penulisan ini adalah penelitian kualitatif. Penelitian ini berfokus pada 5 bangunan tua yang berada di wilayah Kabupaten Aceh Besar, khususnya Kecamatan Kuta Malaka dan Kecamatan Indrapuri. Adapun hasil uji kelayakan instalasi listrik pada bangunan tua di Kabupaten Aceh Besar, dapat diketahui bahwasannya kelima bangunan yang sudah diteliti memiliki kondisi instalasi listrik yang masih layak pakai. Beberapa parameter seperti tegangan, bergainser, kabel, stop kontak dan saklar pada instalasi bangunan tua ini sesuai dengan Standar PUIL. Terdapat beberapa bangunan yang parameternya tidak sesuai dengan nilai ukur grounding. Ada 3 bangunan dengan grounding tidak sesuai dengan nilai standar PUIL, yaitu meunasah Bughu, Masjid Tuha dan rumah Pak Iswandi. Nilai ukur yang dihasilkan dari grounding melebihi standar yang ditetapkan di dalam PUIL
Pemanfaatan Panas Sinar Matahari melalui Charging Spot Terintegrasi Tempat Sampah Non Organik
Authors: Purnomo Purnomo , Tuwoso Tuwoso , Edy Duwi Leksono , Dika Johan Wayan
Published: January 2025

Batu merupakan salah satu kota yang menjadi tujuan destinasi wisata terbaik di Jawa Timur. Sepanjang tahun 2023, jumlah wisatawan mampu melampaui jumlah pada tahun sebelumnya, sehingga diperlukan peningkatan fasilitas yang menunjang aktivitas wisatawan. Keberadaan spot yang mampu menyediakan kelistrikan menjadi prioritas yang harus direalisasikan. Dengan banyaknya jumlah destinasi yang bersifat outdoor, maka potensi renewable energy dapat dimanfaatkan secara optimal. Adapun sumber energi yang dapat dimanfaatkan adalah panas sinar matahari. Penelitian ini bertujuan untuk mengembangkan charging spot dengan memanfaatkan panas sinar matahari yang dapat dijadikan sebagai stasiun pengisi baterai listrik pada handphone. Hasil penelitian ini menunjukkan bahwa charging spot telah berhasil dikembangkan. Charging spot terdiri dari serangkaian beberapa komponen, meliputi solar cell berkapasitas 50 WP sekaligus dijadikan sebagai meja, dua kursi yang terdapat pada bagian samping kiri dan kanan meja, tempat sampah organik, aki kering motor, Solar Charger Controller (SCC), dan port USB yang terdapat pada sisi kanan dan kiri meja. Dengan rata-rata intensitas penerimaan panas sinar matahari selama 8 jam tiap harinya, solar cell dapat memiliki energi sebesar 400 Wh. Dengan energi tersebut, charging spot selama 1 x 24 jam dapat mencharge 36 handphone dengan kapasitas baterai sebesar 3000 mAh.
STRATEGI PENGELOLAAN KELAS DALAM MENINGKATKAN MOTIVASI BELAJAR SISWA SEKOLAH DASAR
Authors: Indriastutik Ninik , Malawi Ibadullah , Chasanatun Fida , Khoiriyatun Nurul
Published: January 2025

Penelitian ini mendeskripsikan strategi guru untuk mengelola kelas meningkatkan motivasi siswa untuk belajar. Penelitian ini menggunakan pendekatan kualitatif fenomenologi dengan guru kelas V SDN Sukosari 02 Dagangan sebagai subjek penelitian. Data yang diperoleh dari penelitian ini berupa observasi dan wawancara terhadap guru kelas, yang dianalisis dengan cara mengklasifikasikan data, mereduksi data, serta menyajikan dan menarik kesimpulan. Hasil penelitian juga mengungkapkan bahwa strategi pengelolaan kelas yang dilakukan guru melalui rencana pengelolaan kelas melalui penyusunan perangkat pembelajaran yang disusun sesuai dengan kebutuhan siswa. Motivasi belajar yang diberikan guru kelas adalah membuat aktivitas pembelajaran yang menarik menggunakan media pembelajaran yang beragam yang mendorong siswa untuk belajar sesuai kemampuan. Penelitian memberikan kesimpulan bahwa motivasi belajar siswa dapat meningkat dengan adanya strategi guru dalam pengelolaan kelas.
 
This study describes the teacher's strategy to manage the class in increasing students' motivation to learn. This study uses a qualitative phenomenological approach with class V teachers of SDN Sukosari 02 Dagangan as the research subjects. The data obtained from this study were in the form of observations and interviews with class teachers, which were analyzed by classifying data, reducing data, and presenting and drawing conclusions. The results of the study also revealed that the class management strategy carried out by teachers through class management plans through the preparation of learning devices that are arranged according to student needs. The learning motivation given by class teachers is to create interesting learning activities using various learning media that encourage students to learn according to their abilities. The study concluded that student learning motivation can be increased by the teacher's strategy in class management.
IMPLEMENTASI NILAI-NILAI PANCASILA SEBAGAI PENDIDIKAN KARAKTER DI SDN SUKOSARI 2
Authors: Nur Aulia Safitri Nurrohmah Widiastuti , Malawi Ibadullah , Chasanatun Fida , Khoiriyatun Nurul
Published: January 2025

Permasalahan karakter seringkali muncul pada anak usia sekolah. Pancasila sebagai ideologi berperan penting dalam membangun karakter masyarakat Indonesia. Karena Pancasila sebagai ideologi yang memegang peranan penting dalam membangun karakter bangsa Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana penerapan nilai-nilai pancasila sebagai pendidikan karakter di sekolah dasar. Metode yang kami gunakan adalah penelitian kualitatif, penelitian ini tidak menggunakan alat statistik, menekankan pada pengamatan dan penelitian lebih lanjut terhadap fenomena. Penelitian kualitatif berfokus pada observasi dan pengumpulan data secara mendalam dengan memberikan penjelasan analitis tambahan. Metode pengumpulan data dalam penelitian ini adalah wawancara. Penelitian dilakukan di SDN Sukosari 2 Dagangan. Hasil penelitian menunjukkan terdapat kendala dalam penerapan nilai-nilai Pancasila di sekolah dasar, misalnya masih ada anak yang kesulitan, ada anak yang mempunyai kebiasaan buruk di luar sekolah dan terbawa ke sekolah. Oleh karena itu, sekolah harus mampu mengatasi kendala tersebut dengan terus melibatkan siswa, membimbing dan mengembangkan siswa, serta membangun kemitraan antara sekolah dan orang tua.
 
Character problems often arise in school-age children. Pancasila as an ideology plays an important role in building the character of the Indonesian people. Because Pancasila as an ideology plays an important role in building the character of the Indonesian nation. The purpose of this study is to determine how the application of Pancasila values ​​​​as character education in elementary schools. The method we use is qualitative research, this study does not use statistical tools, emphasizing observation and further research on phenomena. Qualitative research focuses on observation and in-depth data collection by providing additional analytical explanations. The data collection method in this study is interviews. The study was conducted at SDN Sukosari 2 Dagangan. The results of the study showed that there were obstacles in the application of Pancasila values ​​​​in elementary schools, for example there are still children who have difficulties, there are children who have bad habits outside of school and are carried over to school. Therefore, schools must be able to overcome these obstacles by continuing to involve students, guiding and developing students, and building partnerships between schools and parents.
Assessing the significance of the β-actin gene in tuberculosis diagnosis: an analytical study utilizing anal fistula specimens
Authors: Paliwal Arjun , Gupta Sanjay , Dhingra GK , Kotiyal Shalini , Singh Ankita
Published: January 2025

Fistula samples from suspected tuberculosis (TB) patients play a crucial role in diagnosing advanced extrapulmonary TB. This study examined 70 clinical specimens of anal fistulae suspected of Mycobacterium tuberculosis (MTB) infection using both conventional and molecular methods. The β-actin gene, a housekeeping gene, was assessed for TB detection while microbiological profiling identified acid-fast bacilli. Molecular profiling yielded positive results for both the IS6110 and β-actin genes in 14 samples, suggesting MTB infection. In 13 samples, only the β-actin gene was positive, indicating inflammation caused by other pathogens. Bayesian analysis was conducted to evaluate the diagnostic performance of both gene tests.

The IS6110 gene test showed a sensitivity of 95% and specificity of 98% with a positive predictive value (PPV) of 0.819 and a negative predictive value (NPV) of 0.993. The β-actin gene test demonstrated a sensitivity of 90%, specificity of 99%, PPV of 0.966 and NPV of 0.984. Bayesian calculations indicated a posterior probability of 0.791 for TB in specimens positive for both genes. The findings emphasize the β-actin gene as a potential marker for TB infection. Its detection in TB-negative samples suggests the presence of alternative pathogenic microorganisms. This discovery could be crucial for confirming diagnoses, particularly when radiol
Green Synthesis of zinc oxide nanoparticles using Ocimum basilicum seed extract: characterization and evaluation of antioxidant and antidiabetic activities
Authors: Rexcida Janthark Mary S. , Maneemegalai S.
Published: January 2025

The green synthesis of zinc nanoparticles using plant extract is utilized for its potential biological application and development of novel therapeutics. The biological method of nanoparticle synthesis has gained attention due to its therapeutic applications. This study aimed for the biosynthesis of zinc oxide nanoparticles using an ethanolic extract of Ocimum basilicum seeds and to characterize and to evaluate antioxidant and antidiabetic activity in in-vitro. The ZnO nanoparticles were characterized by UV-visible spectroscopy, X-ray diffraction, Infrared spectroscopy (FTIR) and SEM measurements. The synthesized ZnO NPs possess hexagonal and alkyl chloride compounds that exhibit cubically close-packed crystal structures.

Phytochemical analysis confirmed the presence of flavonoids, terpenoids, tannins, saponins, alkaloids and phenol. The percentage of inhibition for amylase and glucosidase was higher in O.basilicum ZnO NPs. It was found to be 76.10 ±0.83% in amylase and 70.68±0.83 % in the glucosidase inhibition assay. The present study results also showed that synthesized zinc nanoparticles possess antioxidant properties by scavenging the superoxide anion. It concluded that the ZnO nanoparticles synthesized using O.basilicum extract displayed remarkable antioxidant and antidiabetic activities and could be used for therapeutics.
Study of Arsenicum album Homeopathic Medicines: Insights from UV-Visible Spectroscopy
Authors: Sudhir P.K. , Satya Murty S.A.V. , Viswanath R.N. , Venkatesan H.
Published: January 2025

Recent advances in homeopathic medicines have revolutionized the diagnosis and treatment for various health care diseases including severe acute respiratory syndrome. In UV-Vis spectroscopy, the amount of light absorbed is related to the amount of absorbing species present and hence, qualitative information about the medicinal solute species present in Arsenicum album can be obtained. The purpose of this primary research is to elucidate “Whether the medicinal solute species exist at higher potencies where the therapeutic effect is potentially high”.

We have investigated different potencies of Arsenicum album procured from three manufacturers through measurements of optical absorption spectrum using a sophisticated computer controlled UV-Visible 2600 spectrometer. In order to interpret the results, a mother tincture Q sample was used to study the characteristic UV-Vis absorption behaviour of Arsenicum album at various concentrations. The results revealed that irrespective of the potencies, arsenic trioxide medicinal solute species present in the Arsenicum album medicines is in the form of quantum sized nanoclusters. The specific interaction between arsenic trioxide solute species in the Arsenicum album is expected to be reduced upon dilution. Hence, the study of the dilution series of Arsenicum album provides insights. The optical absorption results indicate that arsenic trioxide solutes dilute uniformly in the solvent medium and follow the laws of homeopathy. The study suggests that qualitative analysis of the Homeopathic medicines is possible by UV-Visible spectroscopy.
Antibacterial Activity, Phytochemical Analysis and GC-MS Investigation of Tephrosia purpurea linn Plant Extracts against clinical pathogens
Authors: Kanmani Kannan , Sathyabama Narayanan , Radhakrishanan Natarajan , Sankareswaran Muruganantham
Published: January 2025

The present study of Tephrosia purpurea linn belongs to the family Leguminosa (Fabaceae) screened for secondary metabolites to evaluate its antimicrobial activities using standard procedures. The whole extract with decreasing polarity (Methanol, Chloroform, Petroleum ether, Hexane) was tested on Gram-negative and Gram-positive bacteria like Staphylococcus aureus, proteus mirabilis, Escherichia coli, Salmonella typhi, Klebsiella pneumonae, Pseudomonas aeruginosa. The same extract was tested against Aspergillus niger and Candida albicans. The phytochemical analysis indicated the presence of alkaloids, tannins and saponins in the whole extract of T. purpurea Linn.

The result showed the whole extract of T. purpurea linn showing significant activity against bacterial test models on comparing with the standard antibacterial like amoxicillin and fluconazole. Antifungal activity was found even in different solvent systems with increasing concentration. The ethanolic extract of T. purpurea contained 30 components, according to the results of GC-MS analysis The results reported in the present work show evidence that the flower of T. purpurea Linn possesses antimicrobial activity.
Callistemon viminalis (Sol. ex Gaertn.) exhibiting anti-neuroblastoma activity via molecular interaction of ascorbic acid and 5-lipoxygenase: An in vitro and in silico study
Authors: Rai Nitish , Sinha Saurabh K. , Kumar Neeraj , Dey Sharmistha , Jain Vivek
Published: January 2025

Neuroblastoma is the extracranial of children characterized by diverse clinical manifestations. The present study aimed to investigate the anti-neuroblastoma activity of hydromethanolic extract of Callistemon viminalis (Sol. ex Gaertn.) flower. The anti-neuroblastoma activity of hydromethanolic extract of C. viminalis flower was analysed in SH-SY5Y cell line using MTT assay. The study also evaluated drug-likeness and pharmacokinetic properties of bioactive compounds of extract using SwissADME tool and conducted in silico analysis to determine the molecular interaction between ascorbic acid and 5-LO for explaining the anti-neuroblastoma effect. Significant cytotoxicity was observed in SH-SY5Y cells in a dose and time dependent manner. The ADMET properties of the analysed bioactive compounds of C. viminalis showed them as a suitable drug candidate with appropriate pharmacokinetic properties.

In silico results revealed that ascorbic acid binds into the catalytic domain and interacted with Ser447, Tyr470 and Arg457 of 5-LO with a binding energy of -5.11 Kcal/mol. The total phenol and ascorbate content were found to be 18.71 mg CAE/gm and 16.8 mg/100gm of extract, respectively. Hydromethanolic extract of C. viminalis flower induced cytotoxic effect in human neuroblastoma SH-SY5Y cells via interaction of its constituent ascorbic acid with the 5-LO, one of the important mediators of Neuroblastoma.
In silico prediction of the intrinsic disorder and ligand binding sites of human 3β-hydroxysteroid dehydrogenase type 2 enzyme
Authors: Goswami Achintya Mohan
Published: January 2025

In human, the 3β-hydroxysteroid dehydrogenase (HSD3B)/Δ4,5-isomerase is an important enzyme in steroid hormone biosynthesis. It catalyzed the conversion of Δ5-steroid precursors to respective Δ4-ketosteroids. There were two HSD3B isoenzymes designated as type 1(HSD3B1) and type 2 (HSD3B2), encoded by two different genes located in chromosome 1p13.1. The mutations in HSD3B2 gene could lead to congenital adrenal hyperplasia and impaired steroidogenesis in both the adrenals and gonads leading to varieties of phenotypes. It was known that many proteins had intrinsically disordered regions (IDRs) and sometimes the entire protein lacked a stable tertiary structure, known as intrinsically disordered proteins (IDPs). These IDRs were attractive target for potential drug discovery.

The HSD3B2 was found to possess several IDRs and the regions of IDRs varied according to the algorithm or server used to predict them. The HSD3B2 was predicted to contain two ligand binding sites for NAD and ATP and a single cavity. Some amino acid residues involved in formation of cavity and ligand binding sites were within the intrinsically disordered regions.
HPTLC-A simple and sensitive method to characterize thirty chemotypes and total alkaloid content in Ashwagandha (W. Somnifera)
Authors: Khatak S. , Kumar R.
Published: January 2025

Withania somnifera is not just a name of a herb, it is a multipurpose medicine ranging from a curative agent for cardiovascular disease, cancer, reproductive health care etc. Dried roots and leaves from 30 genotypes collected from nearby States of Madhya Pradesh, Haryana and Rajasthan were extracted using HPTLC for generating chromatograms. Chromatograms were developed using solvent system consisting of chloroform: methanol (90:10) for methanolic extracts while a mobile phase consisted of toluene: ethyl acetate: formic acid (75:18:7) on precoated TLC aluminum plates Si60F254 for all the thirty genotypes. The HPTLC profile of leaves phytochemicals resulted in grouping of various genotypes in five clusters and four clusters using roots.

The genotypes collected did not reveal distinct cluster based on their collection sites, instead were interspersed with each other similar to earlier reports and our previous investigation using TLC. The present research revealed presence of different components in different genotypes. Still the steroidal lactones withaferin-A and withanolide- A reported by earlier researchers were found in maximum genotypes irrespective of their locations.
Fourier Transform of Transfer Matrices of Plane Ising Models
Authors: Khrapov P.V.
Published: January 2025

This work demonstrates the Fourier transform of the elementary transfer matrix of the generalized twodimensional Ising model with special boundary conditions with a shift (screw type) with the form of a Hamiltonian covering the classical Ising model with an external field, as well as models equivalent to models on a triangular lattice with a chessboard type Hamiltonian (the author plans to consider the general form of interaction in the following publication). Its limit representation is obtained in the form of a sum of integral operators with the size of the system tending to infinity. This allows the actual problem of finding the maximum eigenvalue of the limiting elementary transfer matrix (its Napierian logarithm is equal to the free energy of the system) to be brought to finding the maximum eigenvalue of the sum of integral operators of a fairly simple form. This approach can help solve the problems associated with the large size of the transfer matrices.

В работе сделано преобразование Фурье элементарной трансферматрицы обобщенной двумерной модели Изинга со специальными граничными условиями со сдвигом (типа винтовых)с видом гамильтониана, охватывающем классическую модель Изинга с внешним полем, а также модели, эквивалентные моделям на треугольной решетке с гамильтонианом шахматного типа (общий вид взаимодействия автор планирует рассмотреть в следующей публикации). Получено ее предельное представление в виде суммы интегральных операторовпри размерах системы, стремящихся к бесконечности. Это позволяет актуальную задачу нахождения максимального собственного значения предельной элементарной трансферматрицы (ее натуральный логарифм равен свободной энергии системы) свести к нахождению максимального собственного значения суммы интегральных операторов достаточно простого вида. Такой подход может помочь снять проблемы, связанные с большим размером трансферматриц.
The 15-year risk of colorectal cancer: prognostic significance of risk factors of chronic non-communicable diseases with aging
Authors:   Research Institute of Internal and Preventive Medicine  – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Nikitenko T.M. , Shcherbakova L.V. ,   Research Institute of Internal and Preventive Medicine  – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Rymar O.D. ,   Research Institute of Internal and Preventive Medicine  – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Fursov S.A. ,   MD, Professor, Chief oncologist of the Novosibirsk region, Chief physician of the Novosibirsk regional clinic. oncological dispensary, Malyutina S.K. ,   Research Institute of Internal and Preventive Medicine  – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Published: January 2025

Objective: to investigate the prognostic significance of risk factors for chronic non-communicable diseases in the development of colorectal cancer (CRC) in an ageing population cohort (Novosibirsk).
Materials and methods: The study was performed on a representative population sample (Novosibirsk) examined in the HAPIEE project (2003-2005). The analysis included 6061subjects, 152 of whom (73 men, 79 women) had an incident CRC diagnosed during the 15-year follow-up (2003-2015). Cases were identified by linking cancer registry with the cohort database, ICD-10 was used. We used Cox regression models to analyze the association between risk factors and CRC.
Results: The multivariable-adjusted 15-year risk of CRC in men was higher compared to women (HR=1.76; 95% CI:1.12-2.77). The risk of CRC was positively associated with age in both men (HR per year 1.11; 95% CI:1.07-1.15) and women (HR per year 1.09; 95% CI:1.05-1.14). In men with a positive family history of malignant neoplasms (MN) of any location, the risk of CRC was increased (HR=1.90; 95% CI:1.14-3.17). The presence of type 2 diabetes mellitus was associated with the risk of CRC in women (HR=1.97; 95% CI:1.10-3.53).
Conclusions: In studied population cohort aged 45-69, the risk of CRC is positively associated with male gender. Positive associations were also identified between CRC and age in both sexes, the family history of MN of any location in men, and the presence of type 2 diabetes in women.
Keywords: colorectal cancer, smoking, alcohol consumption, blood lipids, type 2 diabetes, body mass index.
nterventional methods for treating chronic pain syndrome in oncological practice: a systematic review
Authors:   PhD, Associate Professor of the Medical Institute of the M.K. Ammosov North-Eastern Federal University, Department of Surgery and Dentistry, Okoneshinkova A.K. , Kalinin A.A. ,   PhD, Associate Professor at the Irkutsk State Medical University, Department of Neurosurgery, Byvaltsev V.A. ,   MD, Professor, Head of the Department of Neurosurgery of the Irkutsk State Medical University; Professor of the Department of Traumatology, Orthopedics and Neurosurgery, Irkutsk State Medical Academy of Postgraduate Education
Published: January 2025

Currently, chronic pain syndrome (CPS) is considered an independent pathology holding significant importance in cancer patients. It has been established that at the early stage of malignant neoplasms (MN), patients experience chronic pain in 35-47% of cases, during full manifestations the number goes up to 78%, and in 98% of patients with generalized forms of malignant neoplasms, chronic pain is the dominant symptom. Despite numerous studies devoted to CPS in oncology, this problem remains relevant.
Purpose of the Study: conducting a systematic review of the literature based on the results of using interventional methods for treating CPS in oncological practice.
Materials and Methods: the authors carried out a systematic search on the subject for articles in English and Russian published between January 1970 and December 2023 using the following databases: Medline, Cochrane Library, and eLibrary.
Results: the systematic review included 15 studies that used interventional treatments for cancer-related CPS. We have established that the use of the analyzed methods in most cases has provided a sufficient level of pain relief in patients with CPS.
Conclusion. Based on the results of the systematic review, we see that there is a need to develop specialized criteria for choosing an interventional method and creating an algorithm for treating drug-resistant CPS in oncology patients.
Keywords: chronic pain syndrome, cancer pain, neurolysis of the celiac plexus, neurodestruction , neuromodulation , palliative care, malignant neoplasm
Features of 24- blood pressure monitoring in internet-dependent adolescents
Authors:   Federal State Budgetary Scientific Institution Scientific Research Institute of medical problems of the North», Krasnoyarsk, Krasnoyarsk territory (Krai), Russia, Shubina M.V. , Tereshchenko S.Y. ,   Federal State Budgetary Scientific Institution Scientific Research Institute of medical problems of the North», Krasnoyarsk, Krasnoyarsk territory (Krai), Russia, Moskalenko O.L. ,   Federal State Budgetary Scientific Institution Scientific Research Institute of medical problems of the North», Krasnoyarsk, Krasnoyarsk territory (Krai), Russia
Published: January 2025

The ever-increasing problem of Internet addiction (IA) in adolescents dictates the need to study its impact on the body, which is intensively developing in this age period, as the most susceptible to various adverse factors. At the same time, the relationship of Internet addiction with the pathology of the cardiovascular system has not yet been sufficiently investigated.
Purpose: In this regard, the purpose of our work was: to identify the main changes in the indicators of SMAD and their relationship with psycho-emotional state in children with Internet addiction.
Materials and methods: 69 children aged 11-18 years were examined with the help of 24-hour ambulatory blood pressure monitoring (ABPM) (TIR-NS-02s "Voskhod") on the basis of the Pediatric Department of the hospital in Krasnoyarsk. Internet addiction was identified by questionnaire using the Chen questionnaire (CIAS). The presence of psychological problems was determined by R. Goodman's questionnaire "Strengths and difficulties".
Results: As a result, children with unadapted Internet use have a tendency to increased variability in blood pressure indicators with an increase in hypotension indicators during the day and hypertension at night, which is a risk factor for the development of arterial hypertension (AH). At the same time, children with deviations in ABPM indicators were more likely than in the control group to have problems with behavior, hyperactivity and problems communicating with peers, as well as higher rates of personal anxiety with low levels of situational anxiety.
Conclusion: Thus, children with ID should be recommended to undergo ABPM in order to early identify established risk factors for the development of hypertension and its prevention with the mandatory use of psychotherapeutic techniques.
Keywords: daily blood pressure monitoring; adolescents; Internet addiction; blood pressure variability; R. Goodman questionnaire "Strengths and difficulties"
Assessment of the resistance of the body of Yakut athletes to hypoxia
Authors:   Yakut Science Centre of Complex Medical Problems (YSC CMP), Yakutsk, Ru, Konstantinova L.I. , Okhlopkova E.D. ,   Yakut Science Centre of Complex Medical Problems (YSC CMP), Yakutsk, Ru, Olesova L.D. ,   Yakut Science Centre of Complex Medical Problems (YSC CMP), Yakutsk, Ru
Published: January 2025

The article reflects the assessment of the body resistance of students of the «North-Eastern Federal University named after M.K. Ammosov», living in the Far North, to hypoxic conditions. 146 people took part in the study – 119 boys and 27 girls. Of these, the study group consisted of 74 student – athletes (59 boys, 15 girls), the control group consisted of 72 students engaged in physical education according to the general program of the University (60 boys, 12 girls). The average age of the surveyed was 21± 2,5 years. To identify the assessment of the body's resistance to hypoxia in Yakutia athletes, the following functional tests were conducted: the Stange test (breath holding on inhalation) and the Genchi test (breath holding on exhalation). The obtained results of the study allowed us to see the prevailing excellent criterion (assessment "excellent") in athletes and the average criterion (assessment "good") in the control group, the results with an unsatisfactory criterion (assessment "unsatisfactory") were less. The conducted assessment shows a positive level of non-specific adaptive capabilities of the respiratory system in the studied students. The functional resistance of the respiratory system to hypoxia in young men was significantly higher than in girls.
Keywords: athletes of Yakutia, students, hypoxia, Stange's test, Genchi test
Provision of specialized medical care in the Republic of Sakha (Yakutia) to patients with cognitive disorders
Authors:   Yakut Science Centre of Complex Medical Problems (YSC CMP), Yakutsk, Ru, Davydova T.K. , Romanova A.N. ,   Yakut Science Centre of Complex Medical Problems (YSC CMP), Yakutsk, Ru, Tatarinova O.V. ,   MD, senior researcher; chief physician of the Republican Clinical Hospital No 3, Nikolaeva T.Ya. ,   MD, head of the Department of Medical Sciences of M.K. Ammosov North Eastern Federal University
Published: January 2025

The article presents an analysis of statistical data on dementia from official sources of state statistics, medical and scientific organizations, as well as the provision of specialized medical care in the Republic of Sakha (Yakutia) to patients with cognitive disorders.
Keywords: neurodegenerative diseases, healthcare organization, specialized medical care, Alzheimer's disease, dementia, cognitive disorder.
Medical and statistical analysis of the prevalence of abortions in Sakhalin Oblast
Authors:   postgraduate student at the Far Eastern State Medical University of the Ministry of Health of the Russian Federation, Khabarovsk, Khe Mi Ran
Published: January 2025

The article analyzes the structure and dynamics of abortions in the Sakhalin region for the period 2013-2022 based on statistical data from the Sakhalin region and the State Federal Statistical Observation No. 13 ‘Information on pregnancy with an abortive outcome’. Despite a significant decrease in the absolute number of abortions in the Sakhalin Region, which is partly due to a decrease in the number of women of fertile age, a high level of abortions per 1,000 women aged 15-49 years remains, almost twice as high as the same indicator in the Russian Federation. There is an increase in the proportion of spontaneous abortions, as well as abortive outcomes associated with other abnormal products of conception, which may indicate problems of women's reproductive health and a decrease in reproductive potential. These changes are also related to the adoption of new statistical forms of registration of abortions in Russia in 2015-2016. In the structure of the terms of termination of pregnancy, the main part during the study period is abortions up to 12 weeks, but there is a tendency to increase the proportion of abortions at a later date of 12-21 weeks - by 44.8%. In turn, not a single case of abortion for social reasons was noted during the study period, but the share of criminal abortion increased, so in 2021 there were seven cases of illegal termination of pregnancy up to 12 weeks and five cases in 2022. There has also been an increase in medical (legal) abortions in non-governmental medical organizations, which indicates the need to develop measures aimed at interaction between state and non-state medical institutions providing abortion services. In addition, there is no data on abortions among first-time pregnancies in non-governmental medical organizations, which leads to an underestimation of this indicator in the overall structure of abortions. According to the data of the State Federal Statistical Observation No. 13, there has been a steady increase in the share of abortions among first-time pregnancies in the structure of all abortions, including in the share of medical (legal) abortions by 31.9% over the period from 2016-2022. This indicates the need to develop preventive measures aimed at increasing the availability of contraception and medical literacy in the field of reproductive health and the formation of responsible reproductive behavior among the population of the Sakhalin region.
Keywords: abortion, fertility, reproductive choice, Sakhalin region
Medical and social portrait of pregnant women with COVID-19 of varying severity
Authors:   PhD in Medical Sciences, Associate Professor, Associate Professor of the Department of obstetrics and gynecology of South Ural State Medical University of the Ministry of Health of the Russian Federation, obstetrician-gynecologist Regional Clinical Hospital No. 2, Ishchenko L.S. , Voropaeva E.E. ,   Grand PhD in Medical Sciences, Professor, Professor of the Department of pathological anatomy and forensic medicine of South Ural State Medical University of the Ministry of Health RF, Deputy Chief Physician for Obstetrics and Gynecology, Regional Clinical Hospital No. 2, Kazachkova E.A. ,   Grand PhD in Medical Sciences, Professor, Professor of the Department of Obstetrics and Gynecology of the South Ural State Medical University of the Ministry of Health RF, Kazachkov E.L. ,   Grand PhD in Medical Sciences, Professor, Head of the Department of Pathological Anatomy and Forensic Medicine of the Federal State Budgetary Educational Institution of the South Ural State Medical University of the Ministry of Health RF, Shamaeva T.N. ,   PhD in Pedagogical Sciences, Associate Professor, Associate Professor of the Department of Mathematics, Medical Informatics, Computer Science and Statistics, Physics of South Ural State Medical University of the Ministry of Health RF, Ishchenko Y.S. ,   4rd year student, Faculty of Pediatrics, South Ural State Medical University of the Ministry of Health RF
Published: January 2025

As a result of a comparative analysis, a number of statistically significant features of the medical and social portrait of pregnant women with COVID-19 of varying severity were identified. An increase in the median age, an increase in the frequency of somatic pathology (chronic arterial hypertension, varicose veins of the lower extremities, overweight, obesity, systemic lupus erythematosus) and polypathies are characteristic as the severity of COVID-19 in pregnant women increases. Mild infection is more common in primigravid women, moderate and severe in pregnant women with a history of childbirth and medical abortion, and extremely severe in multiparous women.
Keywords: new coronavirus infection, COVID-19, pregnancy, social portrait, somatic pathology, gynecological and obstetric history.
Международные территории опережающего развития: новый правовой режим для привлечения зарубежных инвесторов в высокотехнологичные проекты в условиях санкций
Authors: Ступин И.В.
Published: January 2025

Предметом исследования в настоящей статье является предложенный законодательный механизм привлечения и регулирования иностранных инвестиций на территории Дальневосточного федерального округа в части применения специальных мер для защиты прав и интересов хозяйствующих субъектов в условиях санкций со стороны недружественных государств. Объектом исследования выступают проекты нормативных документов, действующая нормативная база и иные документы, регламентирующие вопросы взаимодействия с инвесторами, в том числе зарубежными, на Дальнем Востоке. Автором сделан вывод о том, что нормативная база, регулирующая инвестиционную политику и международную кооперацию на Дальнем Востоке, трансформируется от установления режима благоприятствования для иностранных инвестиций в целом в сторону точечной настройки, в том числе в пользу высокотехнологичных отраслей и с учетом интересов российских отраслевых игроков.

The subject of the study in this article is the proposed legislative mechanism for attracting and regulating foreign investment in the Far Eastern Federal District in terms of applying special measures to protect the rights and interests of business entities in the face of sanctions from unfriendly states. The object of the study are draft regulatory documents, the current regulatory framework and other documents regulating issues of interaction with investors, including foreign ones, in the Far East. The author concludes that the regulatory framework governing investment policy and international cooperation in the Far East is being transformed from the establishment of a favorable regime for foreign investment in general - towards point adjustment, including in favor of high-tech industries and taking into account the interests of Russian industry companies.
К вопросу о промышленной собственности и деприватизации стратегических предприятий в период проведения СВО
Authors: Павликов С.Г.
Published: January 2025

В статье аргументируется суждение о том, что процесс «полной» национализации, за которую так ратуют многие исследователи, вряд ли возможен. Однако деприватизация и переход в собственность государства объектов гражданского оборота, по мнению автора статьи, может иметь место при совокупности двух условий: а) объект приобретен по явно заниженной стоимости, что установлено судебным решением и б) не используется в интересах обороны и безопасности государства, хотя может и должен таким образом использоваться. Обосновано на конкретном примере, что в зависимости от определенных обстоятельств дела такая деприватизация может носить временный характер (в приведенном примере — до окончания СВО).

The article argues that the process of "full" nationalization, so advocated by many researchers, is unlikely to be possible. However, according to the author of the article, deprivatization and transfer of civil turnover objects to state ownership may take place under two conditions: a) the object was acquired at a clearly undervalued price, as established by a court decision, and b) it is not used in the interests of defense and security of the state, although it can and should be used in this way. It is substantiated on a specific example that, depending on certain circumstances of the case, such deprivatization may be temporary (in the given example - until the end of the SVO).
THE FORMATION OF THE MODERN RUSSIAN SCHOOL OF MOSAIC ART: FROM THE CREATION TO THE RESTORATION OF THE MOSAIC “JESUS BLESSING THE CHILDREN” ON THE FACADE OF THE SAINT PETERSBURG STATE INSTITUTE OF CINEMA AND TELEVISION ON PRAVDA STREET
Authors: NESVETAILO IVAN V.
Published: January 2025

The article is devoted to the study of the history of the Russian mosaic school, preceding the creation of the mosaic “Jesus Blessing the Children” on the facade of the Saint Petersburg State Institute of Cinema and Television. The author establishes a close connection between one of the school’s directions and the principles of teaching this technique at the Department of Monumental and Decorative Painting of the Saint Petersburg Stieglitz State Academy of Art and Design, whose graduates carried out the restoration of the work.
YSTEM-STRUCTURAL ANALYSIS OF CONTEMPORARY INTERACTIVE SCULPTURE
Authors: PODOLSKAYA KSENYA S.
Published: January 2025

The article is devoted to the features of the application of system-structural analysis in works of modern interactive sculpture. Changes in approaches to the creation of sculptural objects in the second half of the 20th century and early 21st century, the use of new materials, the development of methods of communication of the work with the surrounding space and the recipient led to the actualisation of the issues of the methodology of studying works of modern art. The article reveals the advantages of system-structural analysis in the study of interactive sculpture. It is noted that the use of this method contributes to a more detailed study of modern artistic forms that have interactivity qualities.
THE PIANO OPUS 33 BY FELIX MENDELSSOHN: A PIANIST’S CURRENT VIEW
Authors: LIANG LANYU
Published: January 2025

The proposed article is addressed, first of all, to modern performers, striving for an original and convincing dialogue with rarely heard musical works. Multifacetedly characterising three piano capriccios by F. Mendelssohn (op. 33), created almost 200 years ago, the author of the article actualises and expands the horizons of multi-vector movement for the pianist: from the origins of the genre to modern improvisation. A bizarre interweaving of traditional and unexpected associations involves the performer in a bright free game, while the “enigmas” of Mendelssohn’s style multiply many times the concert potential of the work presented here. The article is dedicated to the anniversary date: 2024 marks 215 years since the birth of Felix Mendelssohn.
SOCIAL DIFFERENTIATION OF THE SETTLERS OF UFA GOVERNORATE IN THE CONDITIONS OF THE POST-REFORM TRANSFORMATION OF THE 19TH CENTURY
Authors: SAMORODOV DMITRIY P. , ALESHIN PAVEL N.
Published: January 2025

Within the framework of this work, the authors highlight the regional features of the resettlement movement in the post-reform period. Attention is drawn to the social differentiation of migrants, the peculiarities of their adaptation to the culture of the host region, using the example of the peasants of Ufa Governorate, as well as to issues related to their communication in the administrative, economic and everyday contexts during the period of intensification of the movement of migrants. The migration of peasants in this period was a reaction to unfavourable conditions in the agrarian economy. The mass resettlement of a significant part of the population to the eastern territories of the country was inevitably associated with various difficulties arising in the specific environment of the host communities. This stage is also important for studying the factors and models that determine the formation of social and state identity.
GENRE ORIGINALITY OF SEMYON NYARUI’S SONGS
Authors: MNATSAKANYAN ELINA K.
Published: January 2025

The subject of this article is the song heritage of Semyon Nyarui, the first professional Nenets composer. In his work, the unique genres of traditional Nenets musical art transform their previous established appearance, acquiring new forms of existence. In addition, under the influence of European, Russian and Soviet music, the composer’s song creativity is enriched with new genres.
Эконометрический анализ экономической трансформации Китая и динамики глобальных цепочек поставок в рамках стратегии «двойного цикла»
Authors: Гао С.
Published: January 2025

В статье подробно анализируется взаимодействие между экономической трансформацией Китая и динамикой глобальных цепочек поставок в контексте реализации стратегии «двойного цикла». Эта стратегия представляет собой амбициозный подход к переосмыслению роли Китая в глобальной экономике, направленный на создание нового баланса между внутренними и международными макроциклами. В условиях нарастающей глобализации, усиления торговых войн и деглобализации, актуальность данной темы возрастает. Для глубинного изучения влияния стратегии на экономические преобразования была разработана многофакторная модель панельных данных, что позволяет получить более детализированные результаты касаемо изменений в различных секторах экономики. В исследовании применены современные методы анализа, включая регрессионный анализ, метод инструментальных переменных и метод сопоставления баллов склонности, что обеспечивает высокую уровень достоверности и надежности полученных результатов. Особенное внимание уделяется использованию модели двойного разрыва (DID), которая позволяет оценить влияние государственной политики на экономические изменения и динамику глобальных цепочек поставок до и после внедрения стратегии «двойного цикла». В результате, статья представляет собой комплексный анализ и может быть полезна как исследователям, так и политикам, стремящимся понять ключевые аспекты экономической трансформации Китая в условиях быстро изменяющегося мирового порядка. Это исследование также рассматривает возможные сценарии будущих изменений в глобальной экономике и их влияние на структуры поставок. Кроме того, анализируются последствия для различных участников рынка, что открывает новые горизонты для развития бизнес-стратегий в условиях нестабильности. Важность данного исследования также подчеркивается в свете актуальных вызовов, с которыми сталкивается китайская экономика на горизонте ближайших десятилетий.
How Hot Plasmonic Heating Can Be: Phase Transition and Melting of P25 TiO2 from Plasmonic Heating of Au Nanoparticles
Authors: Lu Weigang , Kayastha Rohil , Birmingham Blake , Zechmann Bernd , Zhang Zhenrong
Published: January 2025

Plasmonic heating has been utilized in many applications, including photocatalysis, photothermal therapy, and photocuring. However, the heat dissipation process of the plasmonic nanoparticles (NPs) and the surrounding matrix is complex. How high the temperature of the matrix that surrounds the plasmonic NPs, such as the catalyst and substrate, can be reached is unclear. Herein, we study the dissipation of plasmonic heat generated by resonantly excited gold (Au) NPs dispersed on P25 TiO2 NP porous film in air. Under resonant 532 nm continuous wave (CW) laser irradiation at the surface of the Au-TiO2, the surface evaporation and the aggregation of Au NPs were observed at moderate laser power (10 mW/µm2). This process is accompanied by the phase transition of TiO2. More importantly, the TiO2 nanoparticle film melted, forming melt pools and molten TiO2 matrix. This indicates that the temperature of the TiO2 reached as high as its melting point of 1830 °C. When Au/TiO2 was irradiated with an off-resonance laser at 638 nm, no phase transformation or melting of TiO2 was observed. The temperature calculation showed that the heating generated by Au NPs is not localized. The collective heating from an ensemble of Au NPs in the irradiated area produced a global temperature rise that melted TiO2. Our results suggest that the photothermal effect could be a significant mechanism in the plasmon-assisted photocatalytic reactions.