bluuebunny/crossref_metadata_2025 huggingface dataset:
Social collective organizing: a dynamic capability for the social resilience of a territory
Authors: D’Antone Simona , Crespin-Mazet Florence , Goglio Karine , Fuschillo Gregorio
Published: February 2025

Purpose

This research aims to explore how emergent social collectives contribute to the social resilience of their territory by enacting dynamic capabilities (DCs) to face persistent social adversities untapped by local governments.

Design/methodology/approach

We comparatively analyze two social collectives which emerged to tackle food poverty in Italy (Spesasospesa.org) and cardiac arrest in France (30 min to save lives). Through an abductive research approach, we search DCs allowing social collectives and their founders to mobilize territorial capabilities and self-organize.

Findings

The DCs enabling social collective organizing for the social resilience of territories are: (1) interpreting an external trigger as an opportunity to address persistent social adversities (sensing); (2) mobilizing various territorial capabilities to ideate and implement a solution (seizing); (3) reconfiguring DCs to further deploy and adapt the solution to new domains and geographical areas; and (4) enacting overarching individual and organizational boundary spanning capabilities.

Originality/value

This research outlines social resilience as a DC in social mission-driven organizations rather than within firms, focuses on emergent and heterogeneous social groups and on long-term adversities affecting a territory. Its main contributions highlight: (1) how triggering events impact social collectives’ emergence and resilience capabilities mobilization; (2) how social collective self-organizing and DCs contribute to the social resilience of a territory; (3) how the pair of founders sense an opportunity and activate collective capabilities for social resilience; (4) the crucial role of boundary spanning capabilities; and (5) how territorial characteristics influence the resilient capabilities mobilized.
Digital entrepreneurial enterprises: the evolution of organizational structure
Authors: Cai Ting , Yang Bin , He Jiandu
Published: February 2025

Purpose

On the premise of verifying whether the platformization organization of DEEs is born, this work aims to explore the evolutionary process of the organizational structure of digital entrepreneurial enterprises (DEEs) and to further reveal the drivers of organizational structure evolution from the perspective of data resources.

Design/methodology/approach

The authors use a longitudinal two-case approach to analyze rich archival and interview data from two DEEs in China.

Findings

The findings reveal that the organizational structure of DEEs evolves from hierarchy, network and flatlization to platformization, that the drivers of evolution include building data flow channels, removing barriers of data flow and forming data rules. Meanwhile, the coordination devices in this process have gradually evolved from hierarchy to standard operating procedures, shared culture, norms, etc. to achieve a balance between commercial and creative success.

Originality/value

This work develops a framework for the evolution of organizational structure of DEEs from organization design theory lens and provide some management insights into the development of DEEs.
Overview of mouthfeel from the perspective of sensory scientists in industry
Authors: Ditschun Tanya L. , Riddell Erin , Qin Wei , Graves Karen , Jegede Oyelayo , Sharafbafi Negin , Pendergast Teresa , Chidichimo Darci , Wilson Suzanne F.
Published: February 2025

Mouthfeel is vital in consumer acceptance of foods and beverages. Despite the critical role mouthfeel plays in product development, the concept is often poorly understood and subject to various interpretations. Within this review, five topics of interest are discussed to provide a better understanding of the mouthfeel attribute—the definition, the perception, the importance, the influencing factors, and the methods of measurement of mouthfeel. Mouthfeel encompasses multiple attributes. Although mouthfeel attributes perceived through physical and chemical perceptions, such as cooling and heating, are understood as mouthfeel, attributes perceived through mechanoreceptors, such as creaminess and thickness, are more challenging due to varying opinions on texture and mouthfeel. Other factors, like food composition and temperature, are also vital in understanding the overall effect of mouthfeel in food and beverages. Including all perceived attributes and factors is important for consumer acceptance of products and for developing consistent evaluation of products. Other topics to consider include the dynamic aspects of oral processing and cultural backgrounds as these topics create additional intricacies in defining and understanding mouthfeel perception. Despite the lack of instrumental methodology available to measure mouthfeel attributes, trained panelists can be used to predict facets of mouthfeel in the eating experience. When designing sensory testing for trained panelists, experimental conditions and a product‐specific lexicon are important factors to consider. Overall, understanding of the mouthfeel attributes and their role in consumer preference for different types of food and beverages continues to evolve.
Iron‐Deficiency Anemia Elevates Risk of Diabetic Kidney Disease in Type 2 Diabetes Mellitus
Authors: Huang Bin , Wen Wenjie , Ye Shandong
Published: February 2025

Objective

This study aims to explore the link between iron deficiency anemia (IDA) and diabetic kidney disease (DKD) and assess the safety of iron supplementation. It also investigates key mechanisms and molecules involved in iron deficiency's role in disease development.

Methods

A retrospective analysis was conducted on 1,398 T2DM patients using propensity score matching to identify risk factors for DKD. Mendelian randomization (MR) was used to explore causal relationships between IDA, iron supplementation, liver iron content, and DKD. The GSE27999 dataset was analyzed to examine how an iron‐deficient diet affects kidney‐related gene expression. Key pathways and molecules were identified through GSEA, GO/KEGG, and PPI analysis.

Results

Retrospective data showed a correlation between hemoglobin levels and DKD risk. Logistic regression confirmed that IDA increased DKD risk independently of other factors. MR revealed a causal link between IDA and DKD, with no significant effect from iron supplementation. GSE27999 analysis identified 580 differentially expressed genes, enriched in pathways like cytokine signaling, oxidative biology, and small molecule transport. PPI analysis highlighted 10 key hub genes, including Cyp2d26 and Fgf4.

Conclusion

IDA increases susceptibility to DKD, possibly through oxidative stress and altered small molecule transport. However, iron supplementation does not appear to increase the risk of DKD.
Exploring the Clinical Value of Perioperative ctDNA‐Based Detection of Molecular Residual Disease in Patients With Esophageal Squamous Cell Carcinoma
Authors: Li Jimin , Wu Congcong , Song Yongming , Fan Yuhui , Li Chao , Li Haibo , Zhang Shuangping
Published: February 2025

Objective

To explore the clinical value of molecular residual disease detection based on circulating tumor DNA (ctDNA‐MRD) in the perioperative period of esophageal squamous cell carcinoma (ESCC) and to analyze the tumor escape mechanisms in MRD‐positive cases.

Methods

A total of 35 ESCC patients were prospectively enrolled. Preoperative and postoperative (1 month after surgery) blood and surgical tissue samples were analyzed. ctDNA variants were tracked in plasma to assess ctDNA‐MRD, and whole‐transcriptome sequencing was performed on MRD‐positive and MRD‐negative tissue samples.

Results

Preoperative blood ctDNA was positive in 54.3% of patients, with a 31.6% positive predictive value for recurrence. One month postsurgery, the positive rate of ctDNA was 17.1%, with an 83.3% predictive value for recurrence. Both preoperative and postoperative ctDNA positivity were significant prognostic indicators (HR = 2.78, p < 0.05; HR = 4.42, p < 0.001). Multivariate analysis confirmed ctDNA as an independent prognostic factor (HR = 303.75, p < 0.001). Transcriptomic analysis revealed increased macrophage (W = 15 848; p < 0.01) and follicular helper T (Tfh) cell (W = 10 935; p < 0.01) levels in MRD‐positive patients, suggesting a potential link to immune escape in tumors.

Conclusions

Plasma ctDNA measured 1 month postoperatively in ESCC patients can effectively detect MRD, and ctDNA‐MRD serves as an independent risk factor for postoperative recurrence. The mechanism underlying MRD positivity may involve the polarization of Tfh cells and macrophages, aiding tumor cells in immune escape through the bloodstream.
Sequential Hypothermic and Normothermic Machine Perfusion of Extended Criteria Donors in Liver Transplantation: A Single‐Center Preliminary Experience
Authors: Magistri Paolo , Zamboni Silvia , Catellani Barbara , Guidetti Cristiano , Esposito Giuseppe , Caracciolo Daniela , Odorizzi Roberta , Assirati Giacomo , Olivieri Tiziana , Frassoni Samuele , Bagnardi Vincenzo , Guerrini Gian Piero , Di Sandro Stefano , Di Benedetto Fabrizio
Published: February 2025

Introduction

Liver transplantation (LT) is the sole curative option for liver failure and other primary liver conditions. However, the limited number of suitable donors compared with the growing number of patients requiring LT remains a leading cause of mortality among those on the waiting list. This has resulted in the expansion of criteria for donor eligibility. The sequential combination of ex situ reperfusion, dHOPE, and NMP helps reduce the occurrence of ischemia–reperfusion injury and assess organ viability prior to transplantation.

Methods

This is a retrospective, single‐arm, single‐center study including all cases of liver grafts that underwent sequential perfusion between October 2021 and July 2024. Eligibility criteria for sequential perfusion were extended criteria DBD with macrosteatosis > 35%, use of high‐dose vasopressors during donor ICU stay or episodes of cardiac arrest, hemodynamic instability during procurement, prolonged ischemia time for logistic reasons, as well as DCD showing prolonged fWIT, flow alteration during normothermic regional perfusion (NRP), and DCDs in Maastricht 2 class. Viability was assessed following the Groeningen group criteria.

Results

Thirty‐three cases were included and 16 met the viability criteria at the end of the sequential perfusion and were transplanted. One patient developed an early allograft failure (EAF) and another a primary nonfunction (PNF). All the other patients had a regular postoperative course, with no retransplantation, 56% of the cohort showing no postoperative complication and all currently in good standing, median follow‐up 19 months (range 4–39).

Conclusions

Sequential dHOPE and NMP is a strategy that can help assessing both viability and functionality of liver grafts from high‐risk donors, expanding the donor pool and increasing the opportunities for patients on the waiting list to get a transplant.
Real‐World Utilization of Medications With Pharmacogenetic Recommendations in Older Adults: A Scoping Review
Authors: Ianni Bella D. , Yiu Chin Hang , Tan Edwin C. K. , Lu Christine Y.
Published: February 2025

Pharmacogenetic testing provides patient genotype information which could influence medication selection and dosing for optimal patient care. Insurance coverage for pharmacogenetic testing varies widely. A better understanding of the commonly used medications with clinically important pharmacogenetic recommendations can inform which medications and/or genes should be prioritized for coverage and reimbursement in the context of finite healthcare resources. The aim of this scoping review was to collate previous studies that investigated the utilization rate of medications that could be guided by pharmacogenetic testing. Included studies utilized electronic medical records or claims data to assess pharmacogenetic medication prescription rates for older adults (≥ 65 years old). Identified pharmacogenetic medications were classified according to therapeutic class and assessed for actionability based on the Clinical Pharmacogenetics Implementation Consortium guidelines. Across the 31 included studies, analgesic (n = 29), psychotropic (n = 29), and cardiovascular (n = 27) therapeutic classes were most commonly investigated. Study populations were primarily generalized (48%); however, some studies focused on specific populations, such as, cancer (n = 6), mental health (n = 1), and nursing home (n = 2) cohorts. A total of 215 unique pharmacogenetic medications were reported, of which, 82 were associated with actionable pharmacogenetic recommendations. The most frequent genes implicated in potential drug–gene interactions with these actionable pharmacogenetic drugs were CYP2D6 (25.6%), CYP2C19 (18.3%), and CYP2C9 (11%). Medications most frequently prescribed included pantoprazole (range 0%–49.6%), simvastatin (range 0%–54.9%), and ondansetron (range 0.1%–62.6%). Overall, the frequently prescribed medications and associated genes identified in this review could guide pharmacogenetic testing implementation into clinical practice, including insurer subsidization.
Extremely Low‐Frequency and Low‐Intensity Electromagnetic Field Technology (ELF‐EMF) Sculpts Microtubules
Authors: Lobyntseva Alexandra , Ganaiem Maram , Ivashko‐Pachima Yanina , Barnstable Colin J. , Weisinger Batsheva , Parabucki Ana , Segal Yaron , Shohami Esther , Gozes Illana
Published: February 2025

Aberrant microtubule dynamics coupled with a reduction in Tau‐microtubule interaction are at the core of neuronal injuries resulting in microtubule disruption and aggregates of abnormally phosphorylated Tau. These pathological Tau aggregates define tauopathies such as Alzheimer's disease (AD), as well as the pathological sequelae following traumatic brain injury (TBI), stroke and spinal cord injury (SCI). We hypothesized that differential applications of extremely low‐frequency and low‐intensity electromagnetic field (ELF‐EMF) will change microtubule function. To examine our hypothesis, we pre‐applied ELF‐EMF to a neuroblastoma neuronal cell line later exposed to 4 h of zinc intoxication, modelling Tau‐microtubule dissociation. ELF‐EMF (40 Hz and 1 G; multiple exposure schedules) enhanced microtubule dynamics and increased Tau‐microtubule interaction in the face of zinc toxicity. Complementing these preconditioning neuroprotective effects, concomitant 1 h treatment protocols comparing 3.9 or 40 Hz and 1 G exposure, indicated effects on Tau phosphorylation accentuated with 40 Hz and reduction in beta tubulin isotypes, depending on electromagnetic frequencies, most pronounced at 3.9 Hz. Our results discovered ELF‐EMF modulation on the microtubule cytoskeleton essential for brain health.
Partner strain and support associations with affective reactions to daily stressors
Authors: Witzel Dakota D. , Chandler Kelly D. , Geldhof John G. , Hooker Karen , Stawski Robert S.
Published: February 2025

Objective

We aimed to understand how marital quality and gender influence affective responses to daily stressors (i.e., affective reactivity and residue).

Background

Affective reactions are putative mechanisms through which daily stressors impact long‐term health and well‐being. Understanding which resilience or vulnerability factors (e.g., marital quality, gender) are associated with affective reactions is therefore crucial to promote healthy lives and aging.

Method

Data came from a subsample of married adults (N = 1,335) who participated in both the Midlife in the United States (MIDUS) Study and the associated National Study of Daily Experiences (NSDE). Participants rated their levels of strain and support with their partners in the MIDUS survey. As part of the NDSE, participants subsequently reported their affect and experience of daily stressors over 8 consecutive days.

Results

Partner strain significantly exacerbated associations between previous‐day stressors and negative affect (i.e., affective residue), but not same‐day stressor–affect associations (i.e., affective reactivity).

Conclusion

Findings from this study highlight the importance of marital quality for shaping daily stress and affective well‐being.

Implications

Cultivating couple relationship skills—including decreasing partner strain—in adulthood may provide a means to decrease affective reactions to daily stress and promote short‐ and long‐term health and well‐being.
Pemafibrate improves liver biochemistry and GLOBE scores in patients with primary biliary cholangitis: Nationwide, multicenter study by the Japanese Red Cross Liver Study Group
Authors: Tsuji Keiji , Tamaki Nobuharu , Kurosaki Masayuki , Mori Nami , Takaki Shintaro , Ohya Kazuki , Mashiba Toshie , Ochi Hironori , Kobashi Haruhiko , Ogawa Chikara , Nonogi Michiko , Yoshida Hideo , Akahane Takehiro , Kondo Masahiko , Kasai Toyotaka , Fujii Hideki , Uchida Yasushi , Arai Hirotaka , Tsuchiya Kaoru , Izumi Namiki
Published: February 2025

Aim

We aimed to evaluate the effect of pemafibrate, a selective peroxisome proliferator‐activated receptor‐α modulator, on patients with primary biliary cholangitis (PBC) complicated by dyslipidemia.

Methods

In total, 61 patients with PBC (Add‐on group: 33 patients on ursodeoxycholic acid [UDCA] + pemafibrate combination therapy; Switch group: 28 patients who switched from UDCA + other fibrates to UDCA + pemafibrate combination therapy) were included in the study. Changes in aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma‐glutamyl transferase (GGT), alkaline phosphatase (ALP), and GLOBE scores were retrospectively analyzed from 6 months before to 12 months after treatment. The POISE criteria were also used to evaluate the treatment efficacy after 12 months.

Results

After 12 months of UDCA + pemafibrate combination therapy, AST significantly decreased from 45 ± 3 to 28 ± 3 U/L (p < 0.05), ALT from 49 ± 5 to 32 ± 5 U/L (p < 0.005), GGT from 155 ± 223 to 91 ± 182 U/L (p < 0.005), and ALP from 1.4 ± 0.9 to 0.9 ± 0.8 × upper limit of normal (p < 0.0005) in all patients. ALT, GGT, and ALP levels were significantly lower after 12 months of UDCA + pemafibrate combination therapy in both the Add‐on and Switch groups. After 12 months of combination therapy, the mean GLOBE score of all patients significantly decreased from 0.37 to 0.01 (p < 0.05) and the percentage of patients with a GLOBE score of 0.3 or higher decreased.

Conclusions

In patients with PBC who showed an inadequate response to prior therapy, pemafibrate add‐on or switch therapy improved liver biochemistry and GLOBE scores. Pemafibrate may be useful as a second‐line drug when UDCA alone is inadequate, or as an alternative after combination therapy with other fibrates.
Prediction of early‐onset bipolar using electronic health records
Authors: Wang Bo , Sheu Yi‐Han , Lee Hyunjoon , Mealer Robert G. , Castro Victor M. , Smoller Jordan W.
Published: February 2025

Background

Early identification of bipolar disorder (BD) provides an important opportunity for timely intervention. In this study, we aimed to develop machine learning models using large‐scale electronic health record (EHR) data including clinical notes for predicting early‐onset BD.

Methods

Structured and unstructured data were extracted from the longitudinal EHR of the Mass General Brigham health system. We defined three cohorts aged 10–25 years: (1) the full youth cohort (N = 300,398); (2) a subcohort defined by having a mental health visit (N = 105,461); and (3) a subcohort defined by having a diagnosis of mood disorder or ADHD (N = 35,213). By adopting a prospective landmark modeling approach that aligns with clinical practice, we developed and validated a range of machine learning models, across different cohorts and prediction windows.

Results

We found the two tree‐based models, random forests (RF) and light gradient‐boosting machine (LGBM), achieving good discriminative performance across different clinical settings (area under the receiver operating characteristic curve 0.76–0.88 for RF and 0.74–0.89 for LGBM). In addition, we showed comparable performance can be achieved with a greatly reduced set of features, demonstrating computational efficiency can be attained without significant compromise of model accuracy.

Conclusions

Good discriminative performance for models predicting early‐onset BD can be achieved utilizing large‐scale EHR data. Our study offers a scalable and accurate method for identifying youth at risk for BD that could help inform clinical decision‐making and facilitate early intervention. Future work includes evaluating the portability of our approach to other healthcare systems and exploring considerations regarding possible implementation.
Social media component effects: a commentary on Maheux et al. (2024)
Authors: Jensen Michaeline
Published: February 2025

Maheux et al.s' annual review (2024) summarizes a rapidly evolving literature on the specific components (including content, features and functions) of social media that can help or hinder healthy adolescent development, highlighting how proposed effects of social media components appear to matter more for some adolescents than others. This commentary explores how conclusions of Maheux et al. (2024) can help shape future translational research on what components of social media may facilitate or undermine healthy adolescent development and who is most susceptible to these social media component effects. Future research must also address when and where social media components matter most, situating our understanding within temporal and physical context. Finally, the promise of future research is highlighted on why youth engage with social media components (motivations) and how specific components of social media exert their effects (mechanisms).
Efficacy of Microneedle Fractional Radiofrequency Combined With Topical Insulin for the Treatment of Facial Atrophic Acne Scars: A Split‐Face, Double‐Blinded, Randomized, Placebo‐Controlled Trial
Authors: Rattananukrom Teerapong , Tejapira Kasama , Pomsoong Cherrin , Ratanapokasatit Yanisa , Vachiramon Vasanop
Published: February 2025

Introduction

Topical insulin (TI) has been shown to enhance wound healing by promoting re‐epithelialization and collagen synthesis. However, there have been limited studies addressing its potential use in treating acne scars.

Objectives

To assess the efficacy of combining TI with microneedle fractional radiofrequency (MFR) in the treatment of atrophic acne scars.

Materials and Method

A split‐face, double‐blinded, placebo‐controlled trial involved 30 participants with atrophic acne scars. Each side of the participants' face was randomly treated with a combination of MFR and TI or a placebo every 4 weeks for four consecutive sessions.

Results

Significant improvements in scar volume were observed, with statistical significance at week 12 for MFR combined with TI sides (baseline 18.22 ± 9.86 vs. 16.20 ± 8.58 mm3, p = 0.017) and at week 16 for MFR combined with placebo sides (baseline 18.02 ± 9.24 vs. 15.28 ± 8.21 mm3, p = 0.001). The TI sides exhibited a reduction of 46.77% ± 21.33% in Echelle d’ évaluation clinique des cicatrices d’ acne (ECCA) (p ≤ 0.001), while the placebo sides showed a reduction of 46.39% ± 20.14% in ECCA (p ≤ 0.001). There were no significant differences in melanin, and hemoglobin index between the two groups. No hypoglycemic symptoms were reported.

Conclusion

Combining topical insulin with MFR is safe and could accelerate the early acne scar improvement.
30% Supramolecular Salicylic Acid Improved Symptoms and Skin Barrier in Papulopustular Rosacea
Authors: Wang Zihan , Wu Yutong , Varkani Fatemeh Nozzari , Su Xian , Yang Ziping , Gao Xinghua , Zhang Li
Published: February 2025

Background

Rosacea is a chronic skin condition that affects millions of people worldwide, and its management continues to pose a significant challenge in dermatology.

Aim

In this study, we investigated the efficacy and safety of 30% supramolecular salicylic acid (SSA) as a treatment for papulopustular rosacea, with a particular focus on improving skin lesions, reducing persistent erythema, and enhancing skin barrier function.

Methods

Thirty‐four patients diagnosed with papulopustular rosacea were randomly divided into an experimental group treated with 30% SSA and a control group receiving a placebo. Clinical outcomes were evaluated based on lesion reduction rates, investigator severity assessment (ISA) scores, VISIA red area scores, and skin barrier, including trans‐epidermal water loss (TEWL), sebum levels, stratum corneum hydration, and pH values.

Results

A total of 34 patients were collected for both the experimental and control groups, with no statistical differences in age or disease severity between the groups (p > 0.05). The effective rate was 68.75% in the experimental group (p < 0.01). After treatment, the ISA score was 1.75 ± 0.68 in the experimental group and 2.40 ± 0.83 in the control group, indicating significant improvement (p < 0.05). The improvement rate of the VISIA redness score was 25.1% in the experimental group (p < 0.01). Among the 17 patients who underwent skin barrier function testing. Skin hydration significantly improved on left cheek (p < 0.05), right cheek (p < 0.01), and nose (p < 0.05) after 30% SSA treatment in experimental group. Sebum levels were significantly reduced on both cheeks and forehead (p < 0.05). No statistical differences were observed in other locations. Skin TEWL and pH value showed no changes.

Conclusion

30% SSA reduced papules and pustules in rosacea, improved persistent erythema, and enhanced stratum corneum hydration in the 30% SSA‐treated group compared to the placebo group. No significant differences were observed in TEWL and skin pH values between the two groups. Our findings suggest that 30% SSA is an effective and safe option for managing papulopustular rosacea, offering a well‐tolerated alternative to traditional treatments.
Antimicrobial Administration Practices in Hospitalized Periparturient Goats: A Multicenter Study
Authors: Luethy Daniela , Cabrera Catalina , Coll‐Roman Lisette M. , VanderBroek Ashley R. , Depenbrock Sarah M. , Bauck Anje G. , Kelleman Audrey A. , Stockler Jenna W. , Scully Clare , Wiley Caitlin , Mackay Evelyn E. , Abraham Michelle , Leduc Laurence , Noll Charlene V. , Fecteau Marie‐Eve , Redding Laurel E.
Published: February 2025

Background

Understanding antimicrobial use practices in goats is essential to ensuring appropriate antimicrobial stewardship.

Objective

To describe antimicrobial prescriptions in periparturient does admitted to veterinary teaching hospitals and to determine if any factors were associated with the administration of antimicrobials in general or ceftiofur in particular.

Animals

One hundred ninety‐eight periparturient does presented to nine university veterinary hospitals from October 2021 to June 2022.

Methods

A multicenter cross‐sectional study in a prospective design. Data were collected from questionnaire completed by admitting clinician.

Results

Out of 198 periparturient does included in the study, 153 (77%) received antimicrobials during hospitalization. Commonly administered antimicrobials included oxytetracycline (n = 44, 29%), ceftiofur sodium (n = 43, 28%), ceftiofur crystalline free acid (CCFA; n = 27, 18%), potassium penicillin G (n = 15, 10%), procaine penicillin G (n = 14, 9%), florfenicol (n = 14, 9%), tulathromycin (n = 9, 6%), ampicillin trihydrate (n = 4, 3%), and ampicillin sodium (n = 1, 1%). Cesarean section was associated with antimicrobial administration in general (OR = 5.89; 95% CI = 2.49–13.98, p < 0.01) and with ceftiofur administration (OR = 2.54, 95% CI = 1.25–5.17; p = 0.008). Significant variability in ceftiofur administration by hospital was observed (p < 0.001).

Conclusions and Clinical Importance

Marked heterogeneity was observed in the antimicrobial administration practices in periparturient goats between nine US veterinary teaching hospitals.
Boswellia hesperia sp. nov. (Burseraceae) from Socotra
Authors: Thulin Mats , Weber Michael , Mubarak Sami Ali Mohammed , Rzepecky Alain
Published: February 2025

The new species Boswellia hesperia Thulin, M.H.Weber and Rzepecky is described, illustrated and mapped. It is a dwarf tree, restricted to westernmost Socotra (Yemen), growing on limestone rocks, in which the usually prostrate stems tend to fill out holes and crevices. It differs from B. nana Hepper, another dwarf tree endemic to Socotra but restricted to the easternmost parts of the island, by having leaves densely pubescent with whitish hairs beneath and by its smaller flowers and fruits.
Modified carbon dot‐mediated transient transformation for genomic and epigenomic studies in wheat
Authors: She Linwei , Cheng Xuejiao , Jiang Peng , Shen Simin , Dai Fangxiu , Run Yonghang , Zhu Mengting , Tavakoli Mahmoud , Yang Xueming , Wang Xiu‐e , Xiao Jin , Chen Caiyan , Kang Zhenhui , Huang Jian , Zhang Wenli
Published: February 2025

Genotype restriction poses a significant bottleneck to stable transformation in the vast majority of plant species, thereby severely impeding advancement in plant bioengineering, particularly for crops. Nanoparticles (NPs) can serve as effective carriers for the transient delivery of nucleic acids, facilitating gene overexpression or silencing in plants in a genotype‐independent manner. However, the applications of NP‐mediated transient systems in comprehensive genomic studies remained underexplored in plants, especially in crops that face challenges in genetic transformation. Consequently, there is an urgent need for efficient NP‐mediated delivery systems capable of generating whole plants or seedlings with uniformly transformed nucleic acids. We have developed a straightforward and efficient modified carbon dot (MCD)‐mediated transient transformation system for delivering DNA plasmids into the seeds of wheat, which is also applicable to other plant species. This system facilitates the generation of whole seedlings that contain the transferred DNA plasmids. Furthermore, our study demonstrates that this system serves as an excellent platform for conducting functional genomic studies in wheat, including the validation of gene functions, protein interactions and regulation, omics studies, and genome editing. This advancement significantly enhances functional genomic research for any plants or crops that face challenges in stable transformation. Thus, our study provides for the first time evidence of new applications for MCDs in functional genomics and epigenomic studies, and bioengineering potentially leading to the improvement of desirable agronomic traits in crops.
Oxidative post‐translational modifications of plant antioxidant systems under environmental stress
Authors: Jiménez Ana , Martí María Carmen , Sevilla Francisca
Published: February 2025

Plants are often subject to environmental challenges posed by abiotic and biotic stresses, which are increasing under the current climate change conditions, provoking a loss in crop yield worldwide. Plants must cope with adverse situations such as increasing temperatures, air pollution or loss of agricultural land due to salinity, drought, contamination, and pathogen attacks, among others. Plants under stress conditions increase the production of reactive oxygen‐, nitrogen‐, and sulphur species (ROS/RNS/RSS), whose concentrations must be tightly regulated. The enzymatic antioxidant system and metabolites are in charge of their control to avoid their deleterious effects on cellular components, allowing their participation in signalling events. As signalling molecules, reactive species are involved in plant responses to the environment through post‐translational modifications (PTMs) of proteins, which, in turn, may regulate the structure, function, and location of the antioxidant proteins by oxidative/nitrosative/persulfure modifications of different amino acid residues. In this review, we examine the different effects of these post‐translational modifications, which are emerging as a fine‐tuned point of control of the antioxidant systems involved in plant responses to climate change, a growing threat to crop production.
“Suicide prevention … I hate that word.” Women’s experiences of carceral logics whilst supporting loved ones with suicidal distress in rural Australia
Authors: Finlayson Charlotte
Published: February 2025

INTRODUCTION: Modern neoliberal states discipline subjects through diffuse operations of state power by making individuals both the object of and subject of disciplinary gaze. Constructions of activities like caring, which are overwhelmingly performed by women, are devalued and marginalised.
METHODS: Semi-structured interviews were conducted with carers and workers and volunteers in the welfare and community sector from a rural part of Eastern Australia.
FINDINGS: Women’s experiences of the mainstream mental health system are characterised by carceral logics which limit women’s choice and their relationships with their loved ones, yet some women resist through enacting a form of relational feminist justice.
IMPLICATIONS FOR PRACTICE: This study contributes to broader literature on women’s embodied experiences of legislation and critical mental health scholarship on the harms of coercion in the mental health system in many modern neoliberal states. I encourage social workers practising in neoliberal settings to critically reflect on the impact of carceral logics on women who support loved ones with suicidal distress, and I discuss ways social work practice can promote social justice through centring mutuality in relationships.
“Not social workers, but social fighters”: Navigating the search for macro social work identity in the Aotearoa New Zealand Social Work Journal
Authors: LaMontagne Olivia , Crichton-Hill Yvonne , Maidment Jane
Published: February 2025

Introduction: Given the social work profession’s roots in social justice and recognising the social determinants of wellbeing, macro social work is an essential part of the professional identity.  However, macro work is often a marginalised part of the profession because of an increasing focus on clinical work due to the rise of neoliberalism and practical barriers. 
Methods: To better understand macro social work’s place in the profession, this research sought to assess the historical and current discourses surrounding macro social work in Aotearoa New Zealand. To do this, a qualitative interpretive meta-synthesis was conducted on publications of the Aotearoa New Zealand Social Work Journal since it began in 1965 to 2020. This meta-synthesis was one part of a broader study on macro social work for a PhD thesis.
Findings: The analysis focused on finding journal articles that relate to macro social work to generate themes around how social workers think and feel about the place of macro social work in the profession. Themes around historical trends, scope of practice and the status of the profession were discussed in the context of macro social work and social change. The themes illuminated key tensions between micro and macro social work in the professional identity.
Conclusions: This article makes a case for bridging the divide between micro and macro work and increasing the discussion of macro social work in the professional discourse in the Journal and beyond.
'You Know What, It Is the Money’: Sex Work and Anti-reproductivist Critique
Authors: Bond Peyton
Published: February 2025

What if the inability to refuse care work is baked into the very category of care?’ asks Heather Berg. This article draws from Berg’s ‘reproductivism’ to argue that people who labour on the margins of capitalist society articulate crucial critiques of and resistance to the system of work. Berg’s arguments are brought together with 2020 interviews with indoor sex workers in Aotearoa New Zealand, where sex work was decriminalised in 2003. This article argues that those who reject straight work in favour of work that mightbroadly be better compensated and more flexible, yet remains stigmatised and marginalised, produce a critical standpoint from which to resist and eventually refuse work within a capitalist society, particularly the work of social reproduction.
Futurism without a Future
Authors: Vallelly Neil
Published: February 2025

An interview with the renowned Italian autonomist Marxist philosopher, Franco ‘Bifo’ Berardi. The discussion charts Berardi’s entry into, and expulsion from, the Italian Communist Party in his teenage years and his introduction to the operaismo movement through Mario Tronti’s classic text Workers and Capital (1966). As one of the founders of the pirate station ‘Radio Alice’ and the avant-garde magazine A/traverso, Berardi was heavily involved in the 1977 protests in Bologna, one of the major struggles of the Italian operaismo movement. Berardi also discusses his close friendship with Félix Guattari (including his role in getting Berardi out of prison in Paris) and the influence of Jean Baudrillard on his philosophical practice. Alongside these intellectual and political genealogies, we chat about the war in Ukraine, Israel’s siege on Gaza, and the role psychoanalytic theory might play in understanding politics today. To finish, Berardi outlines his new book Quit Everything (2024) and how its central ideas speak to younger people who now think of themselves as ‘the last generation’.
Selling Out in the High Country
Authors: Lawn Jennifer
Published: February 2025

Eleanor Catton, Birnam Wood, Wellington: Te Herenga Waka University Press, 2023, 423 pp
Among the many pleasures of reading Eleanor Catton’s idiosyncratic fiction is her sheer inventiveness, the sense that she likes to set herself difficult or even improbable writing challenges. Her works hover on the boundaries of established genres—coming of age in her first novel The Rehearsal (2008), crime fiction in The Luminaries (2013)—while refusing to abide by genre conventions. The Rehearsal could be seen as an anti-creative work: set in a performing arts school, the novel presents a caustic take on training in creative arts as ego-eviscerating initiation. The Luminaries arbitrarily (for many readers) fuses the extrinsic numerical patterns of Western astrology with a character-based historical murder mystery cum neo-Victorian sensation novel. Catton’s most recent novel, Birnam Wood, offers another kind of formal conundrum.
Transforming the E-waste Management System
Authors: Ibrahim Sarah
Published: February 2025

The aim of this research is to inform the transformation of the e-waste management in Dunedin by shifting the focus from recycling to activities higher in the waste hierarchy (for example, redesigning, reducing and refurbishing). Previous research has identified the  importance and potential solutions of creating a circular economy for e-waste, but few have addressed the context of Dunedin's social and environmental economy. To gain insight into how Dunedin’s climate influences the e-waste management system, semi-structured interviews were conducted with 12 stakeholders involved in the production, processing and diversion of e-waste. The interviews focused on understanding current e-waste management practices, identified barriers and explored opportunities for collaboration with other stakeholders. A review of global 'good practice' e-waste management provided a benchmark for evaluating and potentially replicating effective e-waste management strategies in New Zealand. This article documents Dunedin’s current e-waste management practices and provides recommendations to guide stakeholders in the e-waste sector. These recommendations particularly focus on supporting product stewardship schemes, prioritising public awareness and education, and encouraging joint solutions. The findings from this article could serve as a model for other regions in New Zealand, promoting sustainable consumption and production patterns.
Quantifying Waste Diversion in Secondhand Stores
Authors: Wilton Grace
Published: February 2025

Secondhand shops are overlooked waste diverters in the sustainability sector, to measure their impact, my research seeks to understand their processes so that quantification strategies can be identified. The Green Island Rummage store is looking for data-gathering strategies so that the carbon emission reductions from their waste diversion efforts can be calculated. This is a difficult issue to tackle because of the pressures faced by secondhand shops due to limited resources. I interviewed local secondhand stores to identify barriers and strategies for waste diversion quantification and then surveyed Rummage employees to determine the applicability of potential measures. This research highlights the pressures faced by secondhand stores and their significance in our move to a circular economy.
Assessment of predatory mite Proprioseiopsis mexicanus as a biocontrol agent against multiple sap-suckling pests
Authors: Yuan Xun , Xie Yonghui , Zhang Bo , Xu Xuenong , Liu Zhengling , Wang Endong , Wei Guo-Shu
Published: February 2025

Proprioseiopsis mexicanus (Garman), a generalist predatory mite, is a highly effective biological control agent applied for pest management worldwide. It performs particularly well against sap-suckling pests, such as Tetranychus urticae, Frankliniella occidentalis, and Bemisia tabaci, which often occur simultaneously in agricultural ecosystems, posing a greater threat to crop production. In this study, we explored the biological control potential of P. mexicanus by investigating the life history parameters, predation, and prey preference of P. mexicanus on T. urticae, F. occidentalis, and B. tabaci, as well as an alternative prey Carpoglyphus lactis. Our results reveal that P. mexicanus feeding on the four prey species could successfully complete development and reproduction. However, P. mexicanus feeding on B. tabaci had a significantly longer developmental time but significantly lower daily eggs laid and lifetime fecundity than on other prey. Conversely, P. mexicanus feeding on F. occidentalis had a similar developmental time as those feeding on T. urticae and C. lactis, but females had a significantly higher lifetime fecundity (i.e., 36.6 eggs). In both non-choice and choice experiments, P. mexicanus consumed significantly more eggs and larvae over other life stages regardless the prey species. When supplied with larvae of different prey species, P. mexicanus significantly preferred T. urticae and C. lactis over F. occidentalis and B. tabaci for feeding. Our results suggest that C. lactis may be utilized as an alternative host prey for laboratory mass rearing of P. mexicanus, and field augmentative release of P. mexicanus in early growing seasons may efficiently suppress the egg and larva populations of T. urticae, as well as larva populations of F. occidentalis if lack of food in the natural environment. These assumptions need to be confirmed in future experiments.
Metallic molybdenum obtained by atomic layer deposition from Mo(CO)6
Authors: van der Zouw Kees , van der Wel Bernhard Y. , Sturm Jacobus M. , Aarnink Antonius A. I. , Wolters Rob A. M. , Gravesteijn Dirk J. , Kovalgin Alexey Y.
Published: February 2025

A feasibility study was conducted into the atomic layer deposition (ALD) of metallic molybdenum from the molybdenum hexacarbonyl [Mo(CO)6] precursor. Without the use of a coreactant, Mo(CO)6 decarbonylates in a nonself-limiting fashion to form molybdenum oxycarbide (MoCxOy) films in the low-temperature regime between 100 and 250 °C. Introducing (atomic) hydrogen as a coreactant, in an attempt to drive self-limiting growth and provide metallic molybdenum films, caused hardly a difference in both film composition and growth kinetics. With ozone as a coreactant, an ALD process was developed to grow molybdenum oxide (MoO3) films without carbon contamination. The MoO3 ALD cycle times were optimized and the existence of an ALD window was investigated. The MoO3 films were subsequently reduced by atomic hydrogen to form metallic molybdenum at temperatures between 150 and 450 °C. The degree of reduction was shown to increase with the reduction temperature, with the limitation that the film exhibited multiple cracks after reduction at 450 °C. Spectroscopic ellipsometry, x-ray photoelectron spectroscopy, and scanning and transmission electron microscopy were employed for thin-film characterization.
Postannealing-induced intermetallic phase formation in NiPt thin films deposited via direct current and high-power impulse magnetron sputtering
Authors: Kühne Alexander , Diyatmika Wahyu , Unutulmazsoy Yeliz , Rudolph Martin , Finzel Annemarie , Gerlach Jürgen W. , Lotnyk Andriy , Abel Bernd , Anders André
Published: February 2025

Intermetallic phases are preferred to reduce the amount of platinum used for catalytic applications as compared to solid solution alloys, due to their stability at elevated temperatures while preserving or even enhancing the catalytic properties. Here, we show a two-step process to form an intermetallic NiPt L10 phase. In this work, NiPt solid solution thin films were fabricated by direct current and high-power impulse magnetron sputtering processes, which allow for precise thickness and chemical composition control. Following deposition, an additional annealing step is used to form the desired intermetallic phase. We show that the required annealing time for intermetallic phase formation is considerably reduced for NiPt thin films with a thickness of 240 nm, as compared to its bulk counterpart.
Electrically tunable nonadiabatic quantum spin pumping in zigzag/bearded graphene nanoribbons
Authors: Zhang Yingran , Yu Jiaming , Ren Chongdan , Tian Hongyu , Xue Liang , Hu Jingguo , Wang Sake
Published: February 2025

We theoretically investigate nonadiabatic quantum spin pumping in zigzag/bearded graphene nanoribbons, in which two bearded graphene nanoribbon regions are deposited by local ferromagnetic insulators to induce spin splitting. We show that spin-polarized currents, spin separation, and even pure spin pumping can be achieved by tuning the driving frequency and the magnetization orientations of the two ferromagnetic insulators. Meanwhile, for the two ferromagnetic insulators with antiparallel/parallel magnetization orientation, the left and right electrodes can simultaneously generate an equal amount of pumped currents with opposite/same spin polarization. Moreover, in the two-parameter spin pumping regime, the flowing directions of the pumped currents can be tuned by the phase difference. This suggests a useful method for manipulating and separating spin in graphene nanoribbons, which is important for spintronic applications.
From Locker Room to Limelight: Exploring College Athlete Heightened Visibility, Branding Challenges, and Safety in the Age of Name, Image, and Likeness
Authors: Brown Katie M. , Esho Adebowale , Sanderson Jimmy
Published: February 2025

The name, image, and likeness (NIL) era in college sports has opened doors for athletes to monetize their popularity through endorsement deals, resulting in a transformation of their status into influencers and celebrities. This paper examines the multifaceted implications of the NIL deals, spotlighting how some college athletes manage their brands and navigate their newfound celebrity status. This analysis delves into the challenges athletes face, such as in-person safety concerns from both peers and strangers, and the responsibilities universities might have to ensure athlete well-being. Moreover, it explores whether institutions have a duty to protect athletes, provide education on brand management and financial literacy, or whether athletes are left to navigate these aspects on their own. By scrutinizing existing guidelines, ethical frameworks, and real-world cases, this paper aims to contribute to the practitioner’s understanding of the complex landscape surrounding college athletes’ heightened visibility and increased popularity, brand management, and safety.