bluuebunny/crossref_metadata_2025 huggingface dataset:
DENTAL HEALTH STATUS OF BETA THALASSEMIA PATIENTS
Authors:   Professor (J) Grade Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, King Georges Medical University, Lucknow, Uttar Pradesh, India., Shastri Dipti , Tandon Pradeep ,   Professor, Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Sciences, King Georges Medical University, Lucknow, Uttar Pradesh, India., Lal Brahm Bhatt Madan ,   Former Head, Department of Radiotherapy, King Georges Medical University, Lucknow, Uttar Pradesh, India., Nigam Nitu ,   Professor (J) Grade, Cytogenetics Unit, Department of CFAR, King Georges Medical University, Lucknow, India.
Published: January 2025

Background: Beta thalassemia is a genetic hematological disorder characterized by chronic anemia, frequent blood transfusions, and iron overload. The systemic complications of this condition significantly impact oral health, leading to craniofacial abnormalities, malocclusion, and an increased risk of dental diseases.

Objective: To evaluate and compare the dental health status of 50 beta thalassemia patients and 50 healthy controls, focusing on overjet, overbite, spacing, periodontitis, mucosal pallor, and DMFT (Decayed, Missing, and Filled Teeth) scores.

Methods: A cross-sectional study was conducted involving 100 participants, comprising 50 beta thalassemia patients and 50 age- and sex-matched healthy controls. Clinical examinations assessed dental parameters, including overjet, overbite, spacing, periodontal health (CPI score), mucosal pallor, and DMFT scores. Data were analyzed using descriptive statistics (mean, standard deviation) and inferential statistics (chi-square test and independent t-tests) with a significance threshold of p < 0.05.

Results:Overjet, Overbite and spacing in beta thalassemia patients exhibited significantly higher as to controls.Periodontitis: Higher CPI scores in beta thalassemia patients were seen compared to controls indicate increased periodontal disease prevalence. Mucosal Pallor: Mucosal pallor scores were significantly higherinpatientsreflecting anemia-related changes.DMFT Scores: Beta thalassemia patients demonstrated higher DMFT scores.

Conclusion: Beta thalassemia significantly affects dental health, manifesting as increased malocclusion, periodontal disease, mucosal pallor, and caries prevalence. These findings underscore the need for integrated dental care tailored to this patient population, including early orthodontic interventions, regular periodontal treatments, and preventive strategies to mitigate oral health challenges.
CHARACTERISTICS OF DIABETES MELLITUS DEVELOPED POST-COVID-19 INFECTION IN ADULTS
Authors:   LD, CDCES, University of Doha for Science and Technology, Doha, Qatar., Abdelaziz Ghada , Mac Nevin Shannan ,   Ph.D, University of Doha for Science and Technology, Doha, Qatar., Yasin Yasin ,   Ph.D, University of Doha for Science and Technology, Doha, Qatar.
Published: January 2025

Background: This integrative review aimed to identify the specific criteria researchers have used in their studies to classify and treat post-COVID-19 Diabetes Mellitus (DM) compared to other types of DM recognized by the International Diabetes Federation (IDF) and the World Health Organization(WHO).

Materials and Methods: In this study, an integrative review of the literature was used. The search strategy began with three electronic databases (CINAHL, Coronavirus Research, and MEDLINE/PubMed). Considering the inclusion criteria, published studies that examined the new onset or early onset of DM post-COVID-19 infection in adults were chosen. Data extraction and analysis were completed on all included studies. The final sample for this integrative review comprised 20 studies.

Results: The findings of this integrative review indicated the demographic and physiological variables associated with post-COVID-19 DM compared to the other types of DM (T1DM, LADA, and T2DM). These findings have been divided into three themes: Theme 1â€”the nomenclature of post-COVID-19 DM Theme 2â€”the individual risk factors for developing post-COVID-19 DM including the subthemes of demographic variables and physiological variables (lab tests) and Theme 3- Post-COVID-19 DM treatment.

Conclusion: In general, the findings of this integrative review highlighted that post-COVID-19 DM might be considered a novel form of DM with unique genetic features. This integrative review called attention to the need for further research on post-COVID-19 DM.
Hemodynamic sclerotherapy in comprehensive management of varicose disease of lower-limb veins in patients with morbid obesity
Authors: Khitaryan A. G. , Kirtanasova E. Ya. , Orekhov A. A. , Gusarev D. A. , Kislyakov V. N. , Veliev K. S. , Chumburidze I. P. , Shatov D. V.
Published: January 2025

Introduction. Endovenous laser ablation combined with sclerotherapy are effective treatment options for varicose veins of the lower limb. However, sclerotherapy is associated with an increased risk of side effects in patients with morbid obesity, which makes it challenging.

Aim. To improve efficiency of the varicose veins of the lower limb treatment in patients with morbid obesity by using the aspects of “hemodynamic sclerotherapy”.

Materials and methods. Prospective comparative study included 109 patients with C3–C5 classes of chronic venous diseases and morbid obesity was performed. All patients were treated with endovenous laser ablation combined with sclerotherapy. In the main group (n = 56) sclerotherapy was performed in the Trendelenburg position, in the control group (n = 53) – in the horizontal position.

Results. The diameter reduction of the great saphenous vein by 22.5% in the Trendelenburg position with 15° incline was statically significant (p < 0.001). The perforating veins reflux in the Trendelenburg position with 15° incline was not detected in 72.3% of patients (p < 0.001). The occlusion rates of the varicose tributaries not treated with sclerosant in the main group was 41% (p = 0.032). In the main group only 12.5% of patients were found to have phlebitis (p = 0.029), the Visual Analog Score (p = 0.036) and local temperature (p = 0.049) were also significantly lower. The incomplete occlusion rate of the varicose tributaries in the main group was only 5.3%; however, the difference was not statically significant.

Discussion. The perforating veins reflux in the Trendelenburg position and the incomplete occlusion of the varicose tributaries were only in obese patients with body mass index more than 55 kg/m2 and C4b–C5 classes.

Conclusions. Sclerotherapy in the Trendelenburg position with the legs elevated at least 15° incline improves the efficiency of the varicose vein’s occlusion in patients with morbid obesity. Sclerotherapy in obese patients with body mass index more than 55 kg/m2 has less effect.
Sorumluluk Duygusu–Davranışına ve Sosyal-Duygusal Öğrenmeye Göre Ergenlerin Sosyal Medya Bağımlılığı ve Mutluluk Düzeylerinin İncelenmesi
Authors: Yuksel-şahin Fulya , Akdemir Altinsoy Melis
Published: January 2025

Sosyal medya kullanımı sosyalleşme sürecinde önemli bir yere sahip olduğundan, ergenler arasında kullanımı oldukça yoğundur. Mutluluk ise ruh sağlığının en önemli kriterlerinden birisidir. Araştırmada, ergenlerin sosyal medya bağımlılığı ve mutluluk düzeyleri sorumluluk duygusuna-davranışına ve sosyal-duygusal öğrenmesine göre incelenmiştir. Araştırmanın çalışma grubunu, İstanbul'daki özel ve devlet ortaokullarına devam eden 505 gönüllü ergenden oluşturmuştur. Araştırma verilerini toplamak için “Sorumluluk Duygusu ve Davranışı Ölçeği”, “Sosyal ve Duygusal Öğrenme Ölçeği”, “Ergenler İçin Sosyal Medya Bağımlılığı Ölçeği” ve “Mutluluk Ölçeği”, kullanılmıştır. Verilerin analizi MANOVA-Pillai’s Trace Testi ile yapılmıştır. Eta kare etki büyüklüğü değerleri de hesaplanmıştır. Çalışmada anlamlılık düzeyi olarak .05 alınmıştır. Araştırmanın sonucunda, sorumluluk duygusu-davranışı ile sosyal-duygusal öğrenme düzeyi düzeyi yüksek olan ergenlerin sosyal medya bağımlılığı düzeyi düşük; mutluluk düzeyleri ise yüksek bulunmuştur. Araştırma bulguları tartışılmış ve önerileri sunulmuştur.
Examining the Impact of Teachers’ Cognitive Load on Student Engagement and Learning Outcomes in Saudi Classrooms
Authors: Alruwaili Reshaa F. , Alasmari Abdullah Abdulrahman
Published: January 2025

Background

Examining the influence of cognitive load on teacher strategies, engagement of students, and the learning experience as a whole is essential in an age of educational reform and rapid technological evolution in instruction to become more effective pedagogues and positively impact student learning outcomes. This study explicates the experience of cognitive load on teachers and their ability to teach and engage students in the Saudi Arabian 21st-century classroom.

Methods

The study employed a qualitative research design to investigate the experiences of the 35 Saudi teachers through an essential initiative stratum of how they were selected in a randomized stratified process to ensure as much diversity as possible in the teaching community throughout Saudi Arabia. Data was collected through open-ended questionnaires and analyzed using thematic analysis to ascertain primary patterns and themes emerging from the data.

Results

The analysis found that (1) cognitive load significantly impacted teachers’ choice of instructional strategies. (2) Classroom performance was also impeded due to cognitive load as teachers struggled to engage and manage the learning of the students inside the classroom; (3) systemic and environmental forces devolving curriculum and integration of technology into instruction increased cognitive demand for the teachers, and (4) teachers employed various adaptive practices to manage their cognitive demands. They demonstrated tremendous resilience and adaptability in their practice.

Conclusion

The study findings have practical implications for educational policy and practice, primarily that educational policy and practice should focus on providing specific assistance and professional learning for teachers managing cognitive load. Finally, based on the findings, the study’s limitations and recommendations for further research are discussed.
The need for judicial protection of the violated rights of the human embryo and fetus as quasi-subjects of law
Authors:   Nikita R. Beshley Chelyabinsk State University, Chelyabinsk, Russian Federation, Arbitration Court of the Sverdlovsk Region, Beshley Nikita R.
Published: January 2025

В данной статье внимание уделяется существующей в рамках действующего законодательства пробельности относительно необходимости развития института судебной защиты в направлении ещё не родившихся детей. Основная цель данного исследования заключается в рассмотрении института судебной защиты с уклоном на необходимость защиты нарушенных прав квазисубъектов права (эмбриона и плода человека). Для достижения поставленной цели необходимо решить следующие задачи: определить признаки института судебной защиты; дать определения понятиям «эмбрион человека» и «плод человека»; рассмотреть судебную практику в целях определения существующих неточностей в действующем законодательстве; предложить пути решения имеющихся законодательных пробелов. Для проведения исследования по выбранной теме были использованы методы общенаучного познания, а также специальные методы: анализ и синтез. В рамках проведённого исследования удалось установить имеющиеся законодательные неточности, возникновение которых связано с быстрым развитием самих общественных отношений, в связи с чем не удаётся вплотную приблизиться к возникающим отношениям. Сделан вывод о необходимости законодательного реформирования, а также предложены рекомендательные пути решения существующих проблем, дабы поставить законодательное регулирование на рельсы с существующей действительностью.
Novelties of administrative and legal regulation of advertising activities in Russia
Authors:   Renat L. Miftakhov Kazan branch of the Russian State University of Justice, Miftakhov Renat L. , Rakhmatullina Renata M. ,   Renata M. Rakhmatullina Kazan branch of the Russian State University of Justice
Published: January 2025

В статье проанализированы результаты новелл административно-правового регулирования рекламной деятельности в России, внесенных Федеральным законом от 2 июля 2021 г. № 347-ФЗ. Раскрыты цели и задачи внесения изменений, исследованы основные нововведения и дана оценка их влияния на эффективность рекламного рынка. Рекламная деятельность играет значительную роль в экономике и общественной жизни, оказывая существенное влияние на формирование спроса на товары и услуги, развитие конкуренции и ин-формирование потребителей. Однако для предотвращения негативных последствий от рекламной деятельности требуется эффективное государственное регулирование, обеспечивающее защиту прав и интересов граждан, общества и предпринимателей. В работе используются методы сравнительного правового анализа, системного и исторического подходов, позволяющие всесторонне изучить новеллы в контексте действующего законодательства и практического применения. В статье проанализированы результаты внесения новелл в административно-правовое регулирование рекламной деятельности в России: усиление контроля за рекламным рынком со стороны ФАС России; повышение качества и достоверности рекламной информации, поступающей к потребителям; снижение рисков для потребителей от недобросовестной рекламы и др. Внесенные новеллы вносят существенные изменения в административно-правовое регулирование рекламной деятельности в России, направленные на повышение эффективности государственного контроля, защиты прав потребителей и совершенствование рекламного рынка. Применение новых норм позволит минимизировать негативные последствия от недобросовестной рекламы и улучшить условия для развития добросовестной конкуренции.
Westerlauwerskfrysk etymologysk griemmank (VII)
Authors: Hoekstra Jarich
Published: January 2025

In this article new or revised etymologies are proposed for Modern West Frisian eart(e) ‘leftover food; leave over food’, rite ‘short period; mood’, ealtsjes ‘slightly, gently’, tsjitte ‘to twitter; to quarrel’, tsiere ‘to quarrel’ and -spa(de), -spar(re), spaai(ke) ‘spade’ as well as for Old West Frisian binnen split ‘having a cut in the inner webbing of the foot (swan mark)’.
Effectiveness of the Facility for Elderly Surveillance System (FESSy) in Two Public Health Center Jurisdictions in Japan: Prospective Observational Study
Authors: Kurita Junko , Hori Motomi , Yamaguchi Sumiyo , Ogiwara Aiko , Saito Yurina , Sugiyama Minako , Sunadori Asami , Hayashi Tomoko , Hara Akane , Kawana Yukari , Itoi Youichi , Sugawara Tamie , Sugishita Yoshiyuki , Irie Fujiko , Sakurai Naomi
Published: January 2025

Background

Residents of facilities for older people are vulnerable to COVID-19 outbreaks. Nevertheless, timely recognition of outbreaks at facilities for older people at public health centers has been impossible in Japan since May 8, 2023, when the Japanese government discontinued aggressive countermeasures against COVID-19 because of the waning severity of the dominant Omicron strain. The Facility for Elderly Surveillance System (FESSy) has been developed to improve information collection.

Objective

This study examined FESSy experiences and effectiveness in two public health center jurisdictions in Japan.

Methods

This study assessed the use by public health centers of the detection mode of an automated AI detection system (ie, FESSy AI), as well as manual detection by the public health centers’ staff (ie, FESSy staff) and direct reporting by facilities to the public health centers. We considered the following aspects: (1) diagnoses or symptoms, (2) numbers of patients as of their detection date, and (3) ultimate numbers of patients involved in incidents. Subsequently, effectiveness was assessed and compared based on detection modes. The study lasted from June 1, 2023, through January 2024.

Results

In both areas, this study examined 31 facilities at which 87 incidents were detected. FESSy (AI or staff) detected significantly fewer patients than non-FESSy methods, that is, direct reporting to the public health center of the detection date and ultimate number of patients.

Conclusions

FESSy was superior to direct reporting from facilities for the number of patients as of the detection date and for the ultimate outbreak size.
Mental Health Changes in US Transgender Adults Beginning Hormone Therapy Via Telehealth: Longitudinal Cohort Study
Authors: Corman Jae Downing , Hughto Jaclyn M W , Shireman Theresa I , Baker Kellan , Steinle Kate , Forcier Michelle
Published: January 2025

Background

Gender-affirming hormone therapy (GAHT) has shown potential for improving mental health outcomes among transgender and gender-diverse adults. How clinical outcomes change among adults receiving GAHT via telehealth across the United States is not well known.

Objective

This study evaluated the relationship between initiating GAHT via a telehealth clinic and changes in depression, anxiety, and suicide ideation over a 3-month period.

Methods

This cohort study evaluated the relationship between initiating GAHT via a telehealth clinic and changes in mental health over a 3-month period. Data were collected at baseline and 3 months later among adults who had their first GAHT visit between August and November 2023. The study included adults aged 18 years and older initiating GAHT for the first time, with a final sample of 342 adults across 43 states (192 initiated estrogen and 150 initiated testosterone therapy). The primary outcomes were depression symptoms using the Patient Health Questionnaire-9 (PHQ-9), anxiety symptoms using the General Anxiety Disorder-7 (GAD-7), and suicide ideation in the past 2 weeks.

Results

Before GAHT initiation, 40% (136/342) of participants reported depression (PHQ-9 ≥10), 36% (120/342) reported anxiety (GAD-7 ≥8), and 25% (91/342) reported suicidal ideation. By follow-up, significant reductions were observed in PHQ-9 (−2.4, 95% CI −3.0 to −1.8) and GAD-7 scores (−1.5, 95% CI −2.0 to −1.0). Among those with elevated symptoms, 40% (48/120) to 42% (56/133) achieved a clinically meaningful response (≥50% reduction in baseline scores), and 27% (36/133) to 28% (33/120) achieved remission (PHQ-9 or GAD-7 score <5). Of those with suicide ideation at baseline, 60% (50/83) had none at follow-up.

Conclusions

This study highlights the important relationship between telehealth-delivered GAHT and mental health, emphasizing the importance of accessible and timely care.
Digital Isolation and Dementia Risk in Older Adults: Longitudinal Cohort Study
Authors: Deng Cheng , Shen Na , Li Guangzhou , Zhang Ke , Yang Shijun
Published: January 2025

Background

Dementia poses a significant global health challenge, characterized by progressive cognitive decline and functional impairment. With the aging global population, dementia prevalence is projected to surge, reaching an estimated 153 million cases by 2050. While the impact of traditional social isolation on dementia risk has been extensively studied, the influence of digital isolation, a phenomenon unique to the digital age, remains underexplored.

Objective

This study aimed to investigate the association between digital isolation and dementia risk among older adults, hypothesizing that higher levels of digital isolation significantly increase the risk of developing dementia.

Methods

We conducted a longitudinal cohort study using data from the National Health and Aging Trends Study (NHATS), analyzing 8189 participants aged 65 years and older from the 3rd (2013) to the 12th wave (2022). Digital isolation was quantified using a composite digital isolation index, derived from participants’ usage of digital devices, electronic communication, internet access, and engagement in online activities. Participants were stratified into low isolation and moderate to high isolation groups. Dementia incidence was assessed using cognitive tests and proxy reports. Cox proportional hazards models were used to estimate the association between digital isolation and dementia risk, adjusting for potential confounders including sociodemographic factors, baseline health conditions, and lifestyle variables.

Results

The moderate to high isolation group demonstrated a significantly elevated risk of dementia compared with the low isolation group. In the discovery cohort, the adjusted hazard ratio (HR) was 1.22 (95% CI 1.01-1.47, P=.04), while the validation cohort showed an HR of 1.62 (95% CI 1.27-2.08, P<.001). The pooled analysis across both cohorts revealed an adjusted HR of 1.36 (95% CI 1.16-1.59, P<.001). Kaplan-Meier curves corroborated a higher incidence of dementia in the moderate to high isolation group.

Conclusions

Our findings indicate that digital isolation is a significant risk factor for dementia among older adults. This study underscores the importance of digital engagement in mitigating dementia risk and suggests that promoting digital literacy and access to digital resources should be integral components of public health strategies aimed at dementia prevention.
Identification of Use Cases, Target Groups, and Motivations Around Adopting Smart Speakers for Health Care and Social Care Settings: Scoping Review (Preprint)
Authors: Merkel Sebastian , Schorr Sabrina
Published: January 2025

BACKGROUND

Conversational agents (CAs) are finding increasing application in health and social care, not least due to their growing use in the home. Recent developments in artificial intelligence, machine learning, and natural language processing have enabled a variety of new uses for CAs. One type of CA that has received increasing attention recently is smart speakers.

OBJECTIVE

The aim of our study was to identify the use cases, user groups, and settings of smart speakers in health and social care. We also wanted to identify the key motivations for developers and designers to use this particular type of technology.

METHODS

We conducted a scoping review to provide an overview of the literature on smart speakers in health and social care. The literature search was conducted between February 2023 and March 2023 and included 3 databases (PubMed, Scopus, and Sociological Abstracts), supplemented by Google Scholar. Several keywords were used, including technology (eg, voice assistant), product name (eg, Amazon Alexa), and setting (health care or social care). Publications were included if they met the predefined inclusion criteria: (1) published after 2015 and (2) used a smart speaker in a health care or social care setting. Publications were excluded if they met one of the following criteria: (1) did not report on the specific devices used, (2) did not focus specifically on smart speakers, (3) were systematic reviews and other forms of literature-based publications, and (4) were not published in English. Two reviewers collected, reviewed, abstracted, and analyzed the data using qualitative content analysis.

RESULTS

A total of 27 articles were included in the final review. These articles covered a wide range of use cases in different settings, such as private homes, hospitals, long-term care facilities, and outpatient services. The main target group was patients, especially older users, followed by doctors and other medical staff members.

CONCLUSIONS

The results show that smart speakers have diverse applications in health and social care, addressing different contexts and audiences. Their affordability and easy-to-use interfaces make them attractive to various stakeholders. It seems likely that, due to technical advances in artificial intelligence and the market power of the companies behind the devices, there will be more use cases for smart speakers in the near future.
Development and Validation of a Generative Artificial Intelligence-Based Pipeline for Automated Clinical Data Extraction from Electronic Health Records: Technical Implementation Study (Preprint)
Authors: Carlisle Marvin N. , Pace William A. , Liu Andrew W. , Krumm Robert , Cowan Janet E. , Carroll Peter R. , Cooperberg Matthew R. , Odisho Anobel Y.
Published: January 2025

UNSTRUCTURED

Background

Manual abstraction of unstructured clinical data is often necessary for granular clinical outcomes research, but is time consuming and can be of variable quality. Large language models (LLMs) show promise in medical data extraction, yet integrating them into research workflows remains challenging and poorly described. We developed and integrated an LLM-based system for automated data extraction from unstructured electronic health record (EHR) text reports within an established clinical outcomes database.

Methods

We implemented a generative AI pipeline (UODBLLM) utilizing a flexible language model interface that supports various LLM implementations, including HIPAA-compliant cloud services and local open-source models. We used XML-structured prompts and integrated using an open database connectivity interface to generate structured data from clinical documentation in the EHR. We evaluated UODBLLM's performance on completion rate, processing time, and extraction capabilities across multiple clinical data elements, including quantitative measurements, categorical assessments, and anatomical descriptions. System reliability was tested across multiple batches to assess scalability and consistency.

Results

Piloted against MRI reports, UODBLLM processed 1,800 clinical documents with a 100% completion rate and an average processing time of 8.90 seconds per report. Token utilization averaged 2,692 tokens per report, with an input-to-output ratio of approximately 6.5:1, resulting in a processing cost of $0.009 per report. UODBLLM had consistent performance across 18 batches of 100 reports each and completed all processing in 4.45 hours. From each report, UODBLLM extracted 16 structured clinical elements, including prostate volume, PSA values, PI-RADS scores, clinical staging, and anatomical assessments. All extracted data was automatically validated against predefined schemas and stored in standardized JSON format.

Conclusion

We demonstrated successful integration of an LLM-based extraction system within an existing clinical outcomes database, achieving rapid, comprehensive data extraction at minimal cost. UODBLLM provides a scalable, efficient solution for automating clinical data extraction while maintaining PHI security. This approach could significantly accelerate research timelines and expand feasible clinical studies, particularly for large-scale database projects.
From Data to Decisions: Predicting Patient Health Outcomes and Risk Using Machine Learning (Preprint)
Authors: Nahin Kazi Sabbir Ahmad
Published: January 2025

UNSTRUCTURED

Predicting health outcomes and classifying patient risks are critical for improving healthcare decision-making. Using a dataset of 30 clinical and lifestyle variables, this study employs a hybrid approach integrating statistical and machine learning models to analyze patient health metrics. Linear regression with interaction terms achieved an adjusted R2 of 0.84 for predicting net health score change (Y1), and deviations from normality prompted exploration of machine learning models, with Random Forest emerging as the most robust alternative. For risk classification (Y2), logistic regression outperformed decision trees, achieving 94.25% accuracy and an AUC of 0.9847, identifying heart rate and blood pressure changes as key predictors. This study demonstrates the power of tailored feature selection and predictive modeling in deriving actionable insights for personalized healthcare.
Karakteristik Pemeliharaan Kuda Andong di Pantai Parangtritis dan Malioboro
Authors: Pranaja Mohammad Rakha Surya , Amperawati Yashinta , Faiza Aliyya Nur , Aliyyah Nabila Shafa Nur , Wenni Asyam Hafidz , Savitri Azalea Perwita , Najwa Nabila Febriyana , Agatha Nur Lailya , Annisa Syifa , Budiariati Vista
Published: January 2025

Kuda andong merupakan salah satu ikon khas Yogyakarta dan memiliki peran besar dalam menarik perhatian wisatawan. Beberapa tempat wisata di Yogyakarta yang menyediakan kuda andong adalah Pantai Parangtritis dan Malioboro. Performa kuda, khususnya pada kuda pekerja dipengaruhi oleh beberapa manajemen pemeliharaan yang saling berkaitan. Manajemen pemeliharaan yang buruk dapat mengakibatkan kuda mudah terinfeksi suatu penyakit, malnutrisi, dan produktivitas rendah. Tujuan dari penelitian ini untuk mengetahui karakteristik pemeliharaan kuda andong di Pantai Parangtritis dan Malioboro guna mengidentifikasi masalah pemeliharaan kuda andong yang ada pada wilayah tersebut beserta solusinya. Pengumpulan data dilakukan dengan pengisian kuesioner oleh 51 kusir andong di Pantai Parangtritis dan Malioboro. Kuesioner terdiri dari 27 pertanyaan terkait manajemen pemeliharaan kuda andong. Selain itu, juga dilakukan pengambilan sampel feses kuda andong untuk pemeriksaan dengan metode sentrifus dan McMaster.
Kajian Potensi Tanaman Herbal Antitrematodosis Berbasis Etnoveteriner Pada Ruminansia
Authors: . Kurnia Solehah , Pratiwi Raras Aprilia , . Husnul Ma'rifah , Pratama Iman Surya
Published: January 2025

Berbagai kendala dalam pengobatan trematodosis pada ruminansia menggunakan agen farmakologi sintetik mendorong penggunaan tanaman herbal berbasis etnoveteriner sebagai alternatif, termasuk di Nusa Tenggara Barat. Jumlah penelitian terkait potensi tanaman herbal sebagai antitrematodosis terus berkembang, namun kajian pustaka masih terbatas. Telaah literatur ini bertujuan untuk mengeksplorasi gambaran penelitian terkait potensi tanaman herbal antitrematodosis berbasis etnoveteriner pada ruminansia, khususnya pada limbah kulit nanas di Nusa Tenggara Barat. Telaah literatur terhadap sumber primer, review dan non riset menunjukkan 7 tanaman herbal yang berpotensi sebagai antifasciolosis dan antiparamphistomiasis (6 studi in vitro dan 1 in vivo). Limbah kulit nanas prospeltif untuk dikembangkan menjadi sedian antitrematodosis seperti granul dan tablet berdasarkan kajian pendahuluan pada aspek  farmakologis dan farmasetik. Berdasarkan temuan dapat disimpulkan bahwa tanaman herbal berpotensi sebagai antitrematodosis berbasis etnoveteriner pada ruminansia, khususnya pada limbah kulit nanas di Nusa Tenggara Barat.
Uji Fitokimia Terhadap Ekstrak Etanol 70% Dan Ekstrak Air Bunga Kecubung (Datura metel L.) Yang Berpotensi Sebagai Bahan Anestesi
Authors: Sudira I Wayan , Samsuri Samsuri Samsuri , Sudisma I Gusti Ngurah , Diana Kadek Leni Martha
Published: January 2025

Anestesi umum dapat didefinisikan sebagai suatu depresi dari sistem saraf pusat (SSP) yang menyeluruh akan tetapi bersifat reversible, yang mengakibatkan hilangnya respon dan persepsi terhadap semua rangsang dari luar. Salah satu agen baru yang berpotensi sebagai bahan anestesi adalah tumbuhan kecubung (Datura metel L.). Penelitian ini bertujuan untuk mengetahui kandungan senyawa kimia yang terkandung dalam ekstrak etanol 70% dan ekstrak air bunga kecubung (Datura metel L.) melalui uji fitokimia dan mengetahui kandungan senyawa kimia yang berpotensi sebagai bahan anestesi. Sampel penelitian berupa bunga kecubung didapat dari daerah Danau Tamblingan, Munduk, Kabupaten Buleleng, Bali yang diekstraksi menggunakan pelarut etanol 70% dan pelarut air dengan menggunakan metode maserasi. Hasil penelitian menunjukkan ekstrak etanol 70% dan ekstrak air bunga kecubung (Datura metel L.) dengan uji fitokimia positif mengandung senyawa alkaloid, saponin, tanin, fenolat, dan flavonoid namun negatif mengandung triterpenoid/steroid serta mengandung senyawa kimia yang berpotensi sebagai bahan anestesi yaitu alkaloid, saponin, tanin, fenolat, dan flavonoid
Populasi Mikroba Pada Saluran Cerna Ayam Pedaging yang diberi Probiotik dan Fitogenik sebagai Feed Additive dalam Ransum
Authors: Daud Muhammad , Yaman Muhammad Aman , Fuadi Zahrul , Mulyadi Mulyadi
Published: January 2025

The aim of this study was to evaluate the population of lactic acid bacteria and pathogenic bacteria (Escherichia coli) in the gastrointestinal tract (duodenum, jejunum, ileum and cecum) of broiler chickens aged 2, 4 and 6 weeks given probiotics and phytogenics in the diet. The study used 96 day old chicks (DOC) which were reared up to the age of six weeks. The study was conducted using an experimental method, using a Completely Randomized Design (CRD) consisting of four ration treatments and four replications. The ration treatments consisted of: R1 (basal ration/control), R2 (basal ration + probiotic), R3 (basal ration + phytogenic), and R4 (basal ration + probiotic + phytogenic). The variables observed were the population of lactic acid bacteria and pathogenic bacteria (Escherichia coli) in the gastrointestinal tract/intestine of broiler chickens (doudenum, jejunum, ileum and cecum) aged 2, 4 and 6 weeks. Data analysis was carried out with one-way variance and continued with Duncan's Multiple Range Test. The results showed that the use of probiotics and phytogenics as feed additives in the diet significantly (P<0.05) increased the of lactic acid bacteria population and decreased the Escherichia coli population in the gastrointestinal tract of broiler chickens aged 2, 4 and 6 weeks of the study. It was concluded that the use of probiotics and phytogenics as feed additives in the ration could have a positive effect on the gastrointestinal tract of broilers.
Prevalensi dan Tingkat Resistansi Silang Golongan Kuinolon Pada Escherichia coli Asal Usap Kloaka Ayam Layer
Authors: Hidayah Nur Nur , Palupi Maria Fatima , Ariyani Novida Ariyani , Indryana Indryana Indryana , Jannah Anna Miftahul , Komariyah Siti Komariyah , Sari Rosana Anita , Ambarwati Ambarwati Ambarwati , Rusmiati Emi Rusmiati , Idrishanty Nafisah Idrishanty , Fanani Fika Asti
Published: January 2025

Escherichia colimerupakan bakteri komensal yang digunakan sebagai parameter monitoring resistansi pada hewan maupun manusia. Selain bersifat komensal, terdapat juga E. coli patogen yang dapatmenginfeksi pada hewan dan manusia. Resistansi E. coli terhadap golongan antibiotik kuinolon berpotensi semakin meningkat. Namun demikian, belum banyak diketahui mengenai tingkat resistansi silang golongan kuinolon pada E. coli patogen khususnya pada ayam layer. Tujuan studi ini adalah untuk mengetahui prevalensi resistansi E. coli pada beberapa jenis kuinolon dan tingkat resistansi silang antar golongan kuinolon dari E. coli asal ayam layer. Sebanyak 360 isolat E. coli asal usap kloaka ayam layer arsip Balai Besar Pengujian Mutu dan Sertifikasi Obat Hewan (BBPMSOH) tahun 2022 dari delapan provinsi diuji kepekaan terhadap siprofloksasin, norfloksasin, enrofloksasin, flumekuin, serta marbofloksasin, dan diuji patogenesitasnya. Uji kepekaan dilakukan dengan menggunakan metode dilusi agar. Prevalensi E. coli resistan terhadap siprofloksasin adalah 45,00% (CI 95%; CI 39,94% - 50,16%), norfloksasin 38,33% (CI 95%; CL 33,46% - 43,45%), enrofloksasin 44,72% (CI 95%; CL 39,67% - 49,89%), flumekuin 42,22%(CI 95%; CL 37,23% - 47,38%), dan marbofloksasin 42,22% (CI 95%; CL 37,23% - 47,38%). Sebanyak 160 (44,44%) merupakan isolat E. coli multiresistan. Tingkatresistansi silang kuinolon dievaluasi dengan statistik kappa (k) berdasarkan resistansi siprofloksasin terhadap norfloksasin, enrofloksasin, flumekuin, dan marbofloksasin. Nilai (k) resistansi silang siprofloksasin terhadap empat kuinolon yang lain adalah 0,86-0,99. Hal ini menunjukkan  tingginya resistansi silang dalam golongan kuinolon. Adanya prevalensi resistansi dan silang kuinolon yang tinggi menunjukkan ancaman yang serius bagi tingkat efikasi antibiotik kuinolon.
Isolation, Identification, and Resistance Test of Escherichia coli to Antibiotics in Ujung Berung Broiler Poultry
Authors: Afifa Kantamaryana Fatia Nasyna , Balia Roostita L , Putranto Wendry Setiyadi
Published: January 2025

Escherichia coli is commensal bacteria in the intestinal of broiler chickens with low virulence. However, mostly pathogenic and cause colibacillosis illness. Inappropriate use of antibiotics in broiler chickens has been widely reported. This research aims to determine the presence of E. coli contamination in the poultry environment and determine the levels of antibiotics resistance of erythromycin, doxycycline, oxytetracycline and neomycin. The research was carried out through isolation and identification of E. coli using EMB media, Gram staining, and biochemical tests. Then, an antibiotic resistance test was carried out using by Kirby-Bauer method. From a total of 10 samples (3 coops), 7 (70%) were positive for E. coli. The positive of 7 which for E. coli, 43% of the isolates came from fresh feces obtained from coops 1, 2, and 3; 43% of the isolates came from litter from coops 1, 2, and 3; and 14% of isolates from soil outside the coop 3. The antibiotic resistance results by Kirby-Bauer method showed that E. coli was 100% resistant to erythromycin, 100% to neomycin, 66.7% to doxycycline, and 66.7% to oxytetracycline throughout isolates from feces and litter. Other results showed that isolates from soil outside coop 3 showed resistance to all antibiotics. Taken together, we concluded the E. coli has been contamination which is proven by antibiotic resistance.
Escherichia coli O157:H7 Bacteria Antibiotic Resistant Isolated from Flies at Food Courts in IPB Dramaga Campus
Authors: Aminudin Muhammad Rizki , Lukman Denny Widaya , Sudarwanto Mirnawati Bachrum , Pisestyani Herwin
Published: January 2025

Several human and animal pathogens transmit into the food chain through houseflies as mechanical vectors, one of which is E. coli O157:H7. E. coli O157:H7 can express Shiga toxin (Stx) which can cause diarrhea, hemorrhagic colitis, and potentially fatal hemolytic-uremic syndrome (HUS) in humans. Some pathogen strains show resistance against various antibiotics, causing complex health problems. This study aims to analyze the presence of antibiotic-resistant E. coli O157:H7 bacteria carried by houseflies (M. domestica) in the food court IPB Dramaga campus area. Detection of E. coli O157:H7 on fly legs using qPCR method based on MU 7.2.3.32-8. E. coli O157:H7 isolates were tested for sensitivity to the antibiotic’s ciprofloxacin, ampicillin, tetracycline, trimethoprim-sulfamethoxazole, cefepime, chloramphenicol, ceftazidime, cefotaxime, and ceftriaxone using the Kirby Bauer disc diffusion method. This study isolated 5 E. coli isolates (5/40; 12.5%), and 2 of them were confirmed as E. coli O157:H7. One isolate of E. coli O157:H7 was resistant against ampicillin and tetracycline, and one isolate was resistant against ampicillin, tetracycline, trimethoprim-sulfamethoxazole, and ceftazidime. The multi-drug resistance was identified only in 1 isolate of E. coli O157:H7.Houseflies collected from the food court have the potential to transmit antibiotic-resistant E. coli O157:H7 around the IPB campus.
Employer's Perception on the Performance of NEUST Tourism Management Graduates: Basis for Career Development Plan
Authors: Duplon Emmanuel J.
Published: January 2025

This study examines how employers perceive tourism graduates, focusing on their workforce readiness, identifying gaps in knowledge and skills, and assessing the alignment between their education and industry requirements. It also explores employer expectations concerning leadership capabilities, sustainable practices, and overall performance in both local and global tourism contexts. The research utilized self-assessment surveys, based on a five-point Likert scale, involving 10 NEUST Tourism Management graduates. Using a descriptive survey method, the study collected data on the graduates’ personal backgrounds, professional performance, and job evaluations provided by their supervisors. Findings consistently revealed high levels of performance and employer satisfaction in areas such as research, teamwork, resource management, critical thinking, cultural awareness, and sustainable practices (SOP 2). Employers also expressed satisfaction with the graduates' time management, resource accessibility, and ability to handle stress related to workloads, conflicts, and workplace transitions (SOP 3).
Sistema judicial y lengua vasca en España: una glotofobia persistente
Authors: Urteaga Eguzki
Published: January 2025

Las últimas sentencias judiciales que han tenido lugar en España, lo más a menudo contrarias al uso preferente de la lengua vasca en la administración pública, han puesto de manifiesto la vascofobia persistente del sistema judicial tanto autonómico como estatal. Efectivamente, los jueces y magistrados han heredado una cultura profesional de la época franquista poco tolerante a las lenguas minoritarias, su nombramiento no está exento de consideraciones políticas y su escaso conocimiento del euskera es palpable. Empero, tanto la Constitución española y los Estatutos de Autonomía como las leyes relativas a la lengua vasca no solo confieren un estatus de cooficialidad a dicha lengua en el conjunto del territorio o en la parte vascohablante, sino que, además, reconocen un conjunto de derechos lingüísticos a quienes hablan la lengua vasca, especialmente en sus relaciones con las administraciones públicas. Todo ello no ha impedido la serie de decisiones judiciales contrarias a estos derechos.
Translenguaje multimodal
Authors: Porteiro Fresco Minia , Báez Montero Inmaculada Concepción
Published: January 2025

Esta nota revisa las metodologías relacionadas con el aprendizaje de lenguas como experiencia lingüística multimodal, en concreto, el uso paralelo de la lengua de signos y la lengua oral para aumentar la competencia comunicativa tanto de personas sordas como de oyentes. Actualmente, se produce una revisión del papel que ejerce la lengua materna en el aprendizaje de otras lenguas mediante conceptos de reciente aparición, como el de translenguaje, que propone que en los hablantes solo existe un sistema lingüístico cuyas características están totalmente integradas en lugar de estar asociadas a una sola lengua. Esta revisión, sumada al contexto actual de fomento del plurilingüismo y el respeto a la diversidad que las administraciones educativas difunden en las escuelas de toda Europa, resulta un marco excepcional para contribuir a la normalización de las lenguas de signos en la sociedad y a incorporar una visión multimodal de la comunicación en el estudio del desarrollo del lenguaje.
Impacto del nearshoring en la actividad económica de México (2020-2023)
Authors: Ramírez Sierra Gabriel Darío , González Martínez Alayn Alejandro , Villegas Rojas Felipe Francisco , Monroy Cruz Miguel Angel
Published: January 2025

Entre los años 2020 y 2023 se evaluó el impacto del nearshoring en México en la industria manufacturera, el empleo y la Inversión Extranjera Directa (IED). El nearshoring se atribuye a factores como el conflicto comercial entre Estados Unidos y China (2017), la disrupción en cadenas de suministro por la contingencia sanitaria por Covid-19 (2020) y la entrada en vigor del Tratado entre México, Estados Unidos y Canadá (T-MEC) (2020). Considerando este último evento como el inicio del nearshoring y utilizando la metodología de Controles Sintéticos Generalizados (CSG) se analizará su impacto.
Large Families: Aspects of Interpersonal Communication between Spouses and Strategies for Dealing with Marriage Conflicts
Authors: Sakharova Tatiana N. , Tsvetkova Natalia A.
Published: January 2025

The article presents the results of a study of the characteristics of marital communication among spouses with many children in comparison with those with one child. It was found that in large families, the level of mutual understanding in communication is higher than that of spouses in single-parent families. Conflict competence, understood as the predominant choice of adaptive strategies in marital conflict, is higher in spouses with many children. They have better developed behaviors than one-child spouses aimed at analyzing difficulties, increa­sing self-esteem and self-control, maintaining or quickly restoring emotional intimacy. It is shown that the most common cause of marital conflicts in single-child families are finances, and in large families – child rearing and household arrangements. The three main causes of marital conflicts in both single-parent and large families include "husband/wife attention deficit", which indicates the high importance of the "psychotherapeutic" function of the family, providing emotional support by spouses to each other.
Evaluating Image Processing Capabilities in the Cloud: A Comparative Study of Microsoft Azure and Google Cloud
Authors: Syeda Zeba Kauser
Published: January 2025

Cloud computing is a transformative paradigm that enables the distribution of processing power, application
execution, and storage across networks of remote computer systems. This model allows for the flexible allocation and release of
IT resources over the internet, offering an affordable solution for both businesses and individuals. Through cloud services, users
can access a variety of offerings, such as Infrastructure as a Service (IaaS), Platform as a Service (PaaS), Software as a Service
(SaaS), and Desktop as a Service (DaaS), with pricing based on actual usage.
In an increasingly competitive market with diverse service options, selecting a long-term cloud provider can be challenging.
Dominant providers like Microsoft Azure and Google Cloud lead this market. This paper provides an in-depth evaluation of the
image processing services offered by these providers, focusing on Azure Custom Vision, Azure Computer Vision, Azure Cognitive
Services, Google Cloud Vision API, and AutoML Vision. The analysis explores the performance and capabilities of these
services, emphasizing their strengths and leadership in cloud technology.
The primary goal of this study is to offer a comparative analysis of Azure and Google Cloud, helping organizations and users
make informed decisions that align with their long-term objectives. In addition, the paper examines the security measures
implemented for Integration Platform as a Service (iPaaS) on both platforms, providing a detailed review of their security
features and protective mechanisms. The study also highlights key parameters such as performance, scalability, usability, cost,
and security to assist organizations in choosing the most appropriate platform for their specific requirements. Case studies and
emerging trends in cloud-based image processing are also covered