bluuebunny/crossref_metadata_2025 huggingface dataset:
Bran from composite grain mixture as an object of deep processing. Part 1. Protein-proteinase complex
Authors: Vitol I. S. , Meleshkina E. P. , Pankratov G. N.
Published: January 2023

Deep processing of grain bran is an important, promising direction that allows the use of by-products (secondary products) of flour milling in order to obtain valuable food components for the creation of enriched food products, as well as specialized grain-based products. Polycomponent bran, obtained during the joint processing of cereals (wheat), legumes (lentils) and oilseeds (flax), in terms of its chemical composition and the state of the proteinproteinase complex, is a unique raw material that can be used for further processing. In particular, it is suitable for the use in producing hydrolysates and other structurally modified products using enzymatic biocatalytic methods. An assessment of the chemical composition and biochemical characteristics of new types of bran showed a high protein content, in which the proportion of the albumin-globulin fraction predominated (78.5-86%), while a significant part of the protein (7.6-10%) was strongly bonded to other biopolymers. The bran proteolytic enzymes acting in the neutral (pH 6.8) and acidic (pH 3.8) pH zones were isolated and studied. It was shown that lentil-flax bran was characterized by the highest proteolytic activity, while the activity of neutral proteinases exceeded the activity of acid proteinases in all three variants: 1.32, 1.37 and 1.56 times, respectively. It was established that protein inhibitors of trypsin and their own proteinases were present in all studied bran types. They inhibited the activity of acid proteinases to a greater extent than neutral ones (% inhibition): 37.5 versus 28.2 (option 1); 32.3 versus 24.5 (option 2); 48.6 versus 32.4 (option 3). The molecular weight, according to gel chromatography, was as follows: neutral proteinases 250,000 200,000 Da, acid proteinases 100,000 75,000 Da. Protein inhibitors isolated from multicomponent bran had a molecular weight of 25,000-20,000 Da. The data obtained will be used in experimental studies on targeted biocatalysis in order to obtain products of a given composition and properties.
Study of morphological features and growth parameters of psychrophilic microalgae and cyanobacteria
Authors: Dolganyuk V. F. , Kashirskikh E. V. , Budenkova E. A. , Andreeva A. P. , Sukhikh S. A.
Published: January 2023

Recently, a question of producing a complex of biologically active substances from microalgae has aroused widespread interest. It is known that microalgae are able to produce a significant amount of exopolysaccharides. The aim of this work was to study morphological features and growth parameters of psychrophilic microalgae and cyanobacteria for the subsequent production of exopolysaccharides. The morphology of microalgae was observed using a binocular microscope. Growth parameters were studied by spectrophotometry; parameters of the culture medium were determined using a pH-meter. Exponential dependency graphs that show the dynamics and expected growth rate of microalgae were built. A rate of growth and polysaccharide biosynthesis in microalgae was determined upon changing the light intensity from 50 to130 mmol/m2/s. The highest level of cell counts in the logarithmic growth phase was up to 0.8 for Scenedesmus obtusiusculus Chod IPPAS S-329. A level of cells also varied in the deceleration phase from 0.25 for Ankistrodesmus acicularis Korsch IPPAS А-218 to 1.8 for Scenedesmus obtusiusculus Chod IPPAS S-329. Microalgae showed a high level of biomass accumulation under alkalophylic conditions. Eukaryotic algae actively photosynthesized at a pH of more than 8.0 and a temperature of 30 °C.

The maximum activity at the level of pH 3.0/3.2 in the lag phase was 100% in C-1509 Nannochloris sp. Naumann. Microalga C-1509 Nannochloris sp. Naumann showed a high level of biomass accumulation under alkalophylic conditions; it photosynthesized at a pH of more than 8.0 and a temperature of 30 °C. It has been proved that neutrophiles can grow at pH lower than 3.0; this corresponds to the results of the experiments with the collection strains of microalgae with biomass productivity of 27.3%. At the alkaline pH values of 8.3-9.0, biomass productivity reduced from 46.0 to 37.2%. It is especially interesting that at the alkaline pH values of 7.5 and 8.0 biomass productivity of microalgae increased, which indicates the optimal growth conditions at this narrow pH range. An ability of microalgae to produce exopolysaccharides opens prospects of their use for practical purposes.
Neophobia: socio-ethical problems of innovative technologies of the food industry
Authors: Smykov I. T.
Published: January 2023

The purpose of this review work is to consider the impact of socio-ethical problems on the acceptance of new food products by potential consumers and the issues  of manufacturers of these products when introducing innovative technologies. The causes  of neophobia of innovative technologies in the food industry are considered on specific examples of the use of nanotechnology, genetic modification technologies, ionization and processing by electromagnetic fields, as well as 3D food printing. It is noted that the public is little aware of innovative food technologies, while its attitude depends on how these technologies are used  and promoted. Proper public  information is critical to the  long-term success of introducing and  developing innovative technologies in the  food industry. It is shown  that the  modern intensive development of information technologies, together with a synergistic set of innovative food technologies, allows  making  a gradual transition to the  production of personalized digital food systems that have functionality, good taste, and safety  with minimal negative impact on the environment.
The problem of grained salmonid roe falsification and ways for its solution
Authors: Abramova L. S. , Kozin A. V. , Guseva E. S.
Published: January 2023

The paper  examines the  problem of falsification of edible  fish products, which concerns producers and consumers worldwide. Food products are most often falsified by imparting them some of the most typical features, for example appearance, upon  the overall  worsening or losing the other most  significant properties of nutritional value, including safety. Market analysis shows that there is a tendency of replacing natural roe with imitated roe by its selling  in metal and glass jars with indication of the address of the Far Eastern producer. It has been established that the protein  content is not higher than one percent upon  imitated roe production using  modern technologies. To establish product authenticity, a methodology for measuring the protein mass fraction in grained salmonid roe by the Kjeldahl method was developed. The metrological characteristic of the developed methodology in three concentration ranges is presented. The used values  can serve for identification of claimed properties with the  specified  indicators of accuracy, trueness, repeatability and reproducibility. In addition to the methodology, product organoleptic indicators are proposed, including assessment of appearance, consistency, taste, odor, as well as specific features of the cooking test  that can serve as distinctive features and are taken into consideration in identification of grained salmonid roe.
Urban agricultural activities, a food system resilience strategy during COVID-19 in Haiti
Authors: Paul B.
Published: January 2023

The COVID-19 crisis is impacting the reconfiguration of food systems at different scales. In poor countries where food insecurity had already been a major problem, the urban population under the lockdown often had to cope alone with shortages of food and access to it. In the poorest country in the Americas, the urban population adapted the food system by intensifying the practice of urban agricultural activities. In this exploratory research, using a sample including urban dwellers that were engaged in urban agriculture and those who were not, we investigated the following question: Did urban agriculture linked to COVID-19 represent an appropriate and innovative strategy for the urban food system resilience? Our results confirm that the Haitian urban population used urban agriculture as an innovative and appropriate food resilience strategy. They produced varieties chosen for their very rapid production character and were able to cope successfully with the crisis, and also have lessons to share with other actors and countries.
Influence of redox processes on the antioxidant activity of the symbiotic starter biomass
Authors: Donskaya G. A. , Krekker L. G.
Published: January 2023

The biological system of the  microbial antioxidant protection is a subject of a certain level of the  physiological oxidative process. To prevent oxidation, a regulator of intracellular metabolism, tripeptide glutathione, is accumulated in cells. Glutathione is very important for the  antioxidant response and maintenance of intracellular redox potential. Its role in several  metabolic adaptive symbiotic processes of yeasts  and lactic acid bacteria is not completely elucidated and is of scientific and practical interest. Glycine is a component of the polypeptide chain and substances that form the  primary structure of glutathione. The aim of this  study  was to determine an effect of the redox processes on the antioxidant activity through regulation of the level of the glutathione constituent, glycine, in a nutrient medium to obtain the microbial biomass of the multicomponent starter culture. As a result of the  performed investigations, a direct dependence between the  antioxidant activity calculated by the  coulometric method and  concentration of glycine  introduced into  the  nutrient medium was determined. It has  been established that addition of 0.2–0.8% of glycine leads to a decrease in the redox potential. The results reflected in this publication show that the process of the development of aerobic  microorganisms in the presence of reducing substances occurs  quite  actively. The number of yeasts  increased from 1.6· 104  to 3.6· 105  CFU/g during 24-hour incubation. An increase in glycine  from  0.5 to 0.8% enhanced the  development of both  anaerobic and  aerobic microorganisms. It has been  found  that an increase in the  glycine  concentration from  0.8% to 1.5% shifted the process toward  the oxidative metabolism; an amount of reduced glutathione in the culture liquid increased practically twofold, while the concentration of oxidized glutathione in the test  sample was in a range  of 0 to 5%. This allows regarding glutathione as a potential regulator of the  redox  processes and antioxidant activity of biomass of lactic acid bacteria and yeasts.
The practice of application and features of the control of oligosaccharides in the production of specialized food products. A review
Authors: Yurova E. A. , Ananyeva N. V.
Published: January 2023

Functional oligosaccharides include various  groups  of carbohydrates with  the  biological activity — an  ability  to modulate gut microbiota due to the  prebiotic, anti-adhesive and anti-inflammatory activities. The unique properties of oligosaccharides explain a wide spectrum of their use in the dairy industry: from food ingredients for imitation  of the  prebiotic activity of human milk oligosaccharides in infant dry milk mixtures to structuring additives, replacers of sugar and fat. When choosing oligosaccharides for inclusion into dairy products, their biological activity and technological properties that depend on a source  and method for extraction of these compounds are assessed. Fructooligosaccharides, galactooligosaccharides, xylooligosaccharides and pectic  oligosaccharides have been  most widely used. When developing recipes of products with stated biological effectiveness, it is necessary to remember that consumption of large  amounts of substances with prebiotic properties can lead to the  gastrointestinal disorder, which requires introducing into  practice the control of the oligosaccharide quantitative content in the product composition. The aim of this  review is analysis of possibilities of using  oligosaccharides in production of specialized  milk-based food products and  methods for controlling quality, safety  and  effectiveness of inclusion of such products into  a diet. The review considers the  existing methods for quantitative identification of oligosaccharides included in the composition of dairy products as functional ingredients. The emphasis is made on the limitations of the introduction of the developed analytical methods into  routine practice of the oligosaccharide control, which is linked with the complexity and multicomponent nature of the food matrix under study. The necessity of the further improvement of methods for quantitative identification of functional oligosaccharides in foods is shown.
Studying an effect of thermal treatment methods on physico-chemical properties of beef depending on aging technology
Authors: Gurinovich G. V. , Khrenov V. A. , Patrakova I. S. , Patshina M. V.
Published: January 2023

Modern methods for aging and thermal treatment facilitate an improvement in beef sensory properties. The aim of the research was to study an effect of different types of thermal treatment on quality of steaks from dry-aged beef. Steaks were obtained from the rib cut from carcasses of grain-fed young bulls; aging duration was 35 days (temperature 0–1 ºС, air relative humidity 74–75%). Aging duration in the control sample was five days (temperature 0–4 ºС, air relative humidity 80–85%). The methods for thermal treatment were as follows: sous vide cooking at 58 ºС, grill heating at 250 ºС, sous vide cooking in combination with grill treatment. During processing, the following parameters were controlled: weight loss by the direct method, hydrophobicity of myofibrillar proteins by the reaction with bromophenol blue, soluble collagen by the method of acid hydrolysis with determination of oxyproline, mass fraction of moisture and fat by the method from one analytical unit, sensory properties by the reference method. According to the data obtained, minimal losses (6.8%) were noticed upon sous vide cooking of dry-aged beef steaks. In combined heating and dry heating on grill, they increased by 6.1% and 12%. More significant weight losses were observed in beef steaks with aging time of five days upon any tested treatment types. For dry-aged beef steaks treated by sous vide and combined heating, a higher content of soluble collagen compared to other samples was established. The results of measuring mass fraction of moisture and fat indicate an increase in the nutritional  value of dry-aged beef steaks. According to the total data obtained with consideration for the results of sensory evaluation, dry-aged beef steaks subjected to sous vide cooking with the following short-term dry heating on grill have higher quality.
INTELLIGENT DELIVERY OF ANTITUMOR DRUGS MEDIATED BY POLYMERIC NANOMICELLES: A REVIEW
Authors: Martins Raquel , Duarte Adriana , Cotinguiba Fernando
Published: January 2023

Cancer therapy represents a challenge, even with the current scientific developments. Over the years, several studies have shown that the application of antitumor drug nanocarriers is an efficient strategy; however, it requires further improvement. Several nanosystems have been developed, some of which are already in use, including liposomes. Polymer-based nanocarriers are still being adjusted to the peculiarities of the human body due to the biological barriers that were encountered by the first systems that were developed. Among them, the formation of corona proteins, clearance by the endothelial reticulum system and kidneys, activation of the immune system, lack of selectivity, and difficult release have been extensively studied and improved with the development of new devices. In this review, we explore the evolution of primary nanocarriers based on polymeric micelles and highlight the gaps that remain in this field to assist in the research of new systems with superior therapeutic indices.
Characterization of Eggshells Nanocatalyst: Synthesized by Bottom-Up Technology
Authors: Masime Jeremiah Odhek , Ogur Erich Okoth , Mbatia Betty N. , Aluoch Austin Ochieng' , Otieno Geoffrey
Published: January 2023

The sol-gel technique was used to prepare the nanocatalyst from waste egg shells for the production of yellow oleander biodiesel. In this study, the physicochemical and catalytic properties of the nanocatalysts were investigated using: X-ray fluorescence spectrometry (XRF), transmission electron microscopy (TEM), the Barrett-Joyner-Halenda (BJH) model to quantify the pore structure of the samples, and Brunauer-Emmett-Teller (BET) to calculate the exact surface area were the techniques used. The results of the EDX, and XRF analysis showed that the synthesized nanocatalyst was majorly CaO. At 90.46 ± 1.73%, this was higher than the control for incinerated eggshells. From TEM images the particles were spherical in shape with particle sizes ranging from ≈ 7 to 41 nm. BET analysis results indicated that the nanocatalyst was mesoporous with surface area, average pore diameter, and pore volume was; 5.54 ± 0.48 m2/g, 18.57 ± 2.16 nm, and ≈ 0.016 ± 0.0 – 0.017 ± 0.0 cm³/g, respectively. The surface area to volume ratios were 3.27 ± 108 m-1, 2.52 ± 108, and 1.95 ± 108 m-1, respectively. Incinerated eggshells highest followed the synthesized nanocatalyst and CaO, respectively. The synthesized eggshell nanocatalyst was found to be a potential nanocatalyst.
Public health risks caused by contamination of local food products
Authors:   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Fazlieva A.S. , Daukaev R.A. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Karimov D.O. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Afonkina S.R. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Allayarova G.R. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Aukhadieva E.A. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation
Published: January 2023

Food safety is a major concern around the world due to toxic metal contamination in food and associated health risks. Vegetables, cereals and baked goods make up a large part of a healthy human diet as vital sources of nutrients, minerals and fiber. Long-term intake of metals with food facilitates their accumulation in the human body. The study aimed to assess health risks for adults and children caused by alimentary intake of chemical elements with local food products. The study was conducted in the Republic of Bashkortostan, which is a territory with a developed agricultural and industrial complex. A total of 524 plant samples were selected and analyzed to identify levels of lead, cadmium, copper, zinc, iron, nickel and aluminum in them by using atomic absorption analysis. Samples included bakery and cereal products sold in the republic and vegetable products from private farms. The article describes the results of hygienic assessment with its focus on contents of essential and toxic elements in locally produced foods. Intake of contaminants with local food products was established based on the data on average food consumption per capita. We determined contributions made by two groups of traditional mass-consumption products to the total exposure that influences health of people living in different districts across the republic. The study established the total hazard quotient of non-carcinogenic effects to be higher than its threshold vale and to equal 3.43 for children and 1.54 for adults. The greatest contributions to the total hazard quotients were made by copper (45 %) and cadmium (30 %). Our as-sessment of carcinogenic risks caused by intake of contaminants with foods revealed that the total health risk as per the median value corresponded to its permissible level
On sufficient substantiation for maximum permissible level of zilpaterol in meat products
Authors: Zelenkin S.E. , Shur P.Z. , Kiryanov D.A. , Chigvintsev V.M. , Ustinova O.Yu. , Fokin V.A. , Suvorov D.V. , Fedorenko E.V.
Published: January 2023

The Joint FAO/WHO Expert Committee recommends the maximum permissible level of zilpaterol in meat to be fixed at 0.5 µg/kg. This level is substantiated by results of analysis described in several research works. Nevertheless, substantiation provided for this recommended standard requires a detailed discussion. In this study, we aimed to analyze substantiation of FAO/WHO suggestions on the maximum permissible level (MPL) of zilpaterol in meat as per health risks for consumers. Our analysis of research results revealed that the no observed adverse effect level (NOAEL) and the lowest observed adverse effect level (LOAEL) were established allowing for negative effects on various organs and systems in the body. The lowest observed adverse effect level (LOAEL) under acute exposure was taken as a baseline for establishing MPL. This level produces negative effects on the nervous system (developing tremor). However, modifying factors used in MPL development have not been supported with solid argument. We also established that the LOAEL identified for the nervous system under acute exposure was much lower than NOAELs for other organs and systems under chronic exposure. Therefore, the aforementioned research results seem rather controversial. It is necessary to consider another additional factor, which is wide prevalence of cardiovascular diseases among adult population and risk factors that cause their development. Therefore, potential adverse effects on the cardiovascular system are no less important and we should note that they have been reliably detected both in acute and chronic experiments. In this study, we modeled a health risk caused by adverse effects of consuming meat products with residual zilpaterol levels; the risk was modeled in dynamics. The modeling experiment established that an impermissible health risk of adverse health outcomes in the cardiovascular system occurred even under exposure to zilpaterol in levels close to the lowest limit of sensitivity. Consequently, it seems rather premature to accept the maximum permissible level for zilpaterol in meat that is being suggested at present. It is recommended to cut its level down to the lowest limit of detection.
К оценке индекса накопления цитогенетических нарушений при воздействии ком-плекса неблагоприятных производственных факторов на организм металлургов
Authors:   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Vlasova N.V. , Masyagutova L.M. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation,   Bashkir State Medical University, 3 Lenina Str., Ufa, 450008, Russian Federation, Abdrakhmanova E.R. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation,   Bashkir State Medical University, 3 Lenina Str., Ufa, 450008, Russian Federation, Rafikova L.A. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation, Chudnovets G.M. ,   Ufa Research Institute of Occupational Health and Human Ecology, 94 Stepana Kuvykina Str., Ufa, 450106, Russian Federation
Published: January 2023

Metallurgy is a major economic branch in Russia with more than 4000 enterprises operating in it and seventy percent of them being city-forming ones. This study focuses on cytological assessment of the oral mucosa and secretion from the middle meatus mucosa in workers employed in metallurgy. The aim of this study was to investigate cytological laboratory indicators in workers employed in metallurgy under exposure to adverse occupational factors. A clinical and diagnostic examination of workers employed at a metallurgical plant in Bashkortostan was performed in 2019–2020; it involved cytological studies of the oral mucosa (buccal epithelium) and the middle meatus mucosa (rhinocytogram). In this study, we applied the Index of cytogenetic disorders accumulation (Iac) that allows for cellular kinetics indicators. The overall hygienic assessment of working conditions for workers employed at the analyzed metallurgic plant corresponds to the hazard category 3.2–3.3 in accordance with the criteria outlined in the Guide R (harmful, class 2 or 3). The research results revealed cytogenetic disorders of buccal epithelial cells in the workers who had contacts with adverse occupational factors. Low likelihood of cytogenetic disorders was established for 66.67 % of the workers; moderate, 9.2 %; high, 23.81 %. We assessed rhinocytograms of the workers exposed to adverse occupational factors and revealed some signs of allergic inflammation characterized with high eosinophil count. The research results confirm high significance of diagnostic procedures for developing an algorithm for screening examinations of working population as well as indicators of health disorders under exposure to adverse occupational factors (noise, heating microclimate, industrial dust, gaseous chemicals).
A conceptual scheme of a predictive-analytical model for describing incidence of west nile fever based on weather and climate estimation (exemplified by the Volgograd region)
Authors:   Volgograd Scientific Research Anti-Plague Institute, 7 Golubinskaya Str., Volgograd, 400131, Russian Federation, Zhukov K.V. , Nikitin D.N. ,   Volgograd Scientific Research Anti-Plague Institute, 7 Golubinskaya Str., Volgograd, 400131, Russian Federation, Kovrizhnykh D.V. ,   Volgograd State Medical University, 1 Pavshikh Bortsov Sq., Volgograd, 400131, Russian Federation, Viktorov D.V. ,   Volgograd Scientific Research Anti-Plague Institute, 7 Golubinskaya Str., Volgograd, 400131, Russian Federation, Toporkov А.V. ,   Volgograd Scientific Research Anti-Plague Institute, 7 Golubinskaya Str., Volgograd, 400131, Russian Federation
Published: January 2023

The present study focuses on weather and climatic factors influencing the incidence of West Nile fever (WNF) in the Vol-gograd region. We aimed to describe a relationship between these factors and the WNF incidence and to create a conceptual scheme of a predictive-analytical model for making forecasts how an epidemiological situation would develop in future. According to this aim, we selected an approach that involved identifying a statistical correlation between the analyzed factors and the WNF incidence in the Volgograd region and estimating the power of this correlation. The study primarily relied on using correlation analysis that was followed by assessing authenticity of the study results. The obtained data made it possible to establish that air temperature was a leading potentiating factor in the Volgograd region. It produced certain effects that varied in their intensity on a whole set of abiotic and biotic factors (water level and temperature, numbers and activity of carriers, how fast the virus amplifies in carriers, etc.). The study established that use of comprehensive statistical data (average monthly indicators) allowed more precise esti-mation of correlations. We also considered and confirmed a hypothesis about a delayed effect produced by air temperature on population incidence and numbers of West Nile virus carriers in the Volgograd region; it was the most apparent in years with the maximum numbers of infected people (1999, 2010, and 2012). We revealed a statistical correlation between air temperature and average annual water level and the WNF incidence among population and the number of West Nile virus carriers. There was a strong correlation between the number of carriers and the WNF incidence. A conceptual scheme of a predictive model for determining rate of the WHF incidence in Volgograd region was created based on the statistical analysis results.
As viagens de Caliban na América Latina: um estudo comparado entre Oswald de Andrade e Aimé Césaire
Authors: Rafael Marino
Published: January 2023

a peça A tempestade, de Willian Shakespeare, teve ressonâncias profundas e diversas de seu contexto de origem. Prova disso é que ela e seus personagens foram utilizados sistematicamente, e num espaço temporal alargado, para se pensar metáforas sobre a América – suas condições de colonização, disputas geopolíticas, construção de identidades e cristalização de imagens a respeito do continente. O caso que aqui temos em tela é um recorte deste quadro geral: pretendemos, aqui, estudar o chamado momento caliban do pensamento latino-americano. De forma mais precisa, intentamos fazer um estudo comparado das experiências intelectuais de Oswald de Andrade e Aimé Césaire. O nosso objetivo com este estudo comparativo é oferecer uma leitura sobre a constituição, potencialidades e limitações do calibanismo – que foi e é essencial para conformações de imagens e ideias sobre a América Latina.
O Feminismo Decolonial de María Lugones
Authors: Carvalho Guilherme
Published: January 2023

O estudo aborda as concepções de María Lugones sobre colonialidade de gênero e interseccionalidade, enfatizando sua perspectiva feminista decolonial. Na análise do sistema colonial/moderno de gênero a partir da perspectiva da colonialidade, María Lugones desenvolve a concepção de “colonialidade de gênero”. Em sua teoria crítica do sistema de gênero colonial/moderno enfatiza-se a intersecção de raça, classe, gênero e sexualidade, considerando a “colonialidade de gênero” como característica estrutural das sociedades colonizadas. Assim, na teoria da interseccionalidade, múltiplas formas de opressão constituem relações complexas de poder. Essa perspectiva teórica estabelece uma relação entre as categorias conceituais de gênero, raça, classe e sexualidade. A epistemologia do Feminismo Negro é uma referência para a concepção de interseccionalidade. Na perspectiva decolonial de María Lugones, a compreensão da colonialidade, a noção de gênero e as relações de poder constituem a base da ideia de múltiplas opressões interseccionadas. A teoria interseccional de Lugones mostra as resistências às relações de poder, associadas a experiências e práticas de coalizão.
Considerações sociolinguísticas sobre o uso do ‘vos’ no oriente boliviano
Authors: Maranhão de Castedo Tatiana , Gomes da Silva Carolina , Marques de Lucena Rubens
Published: January 2023

Este artigo tem como objeto de estudo o uso do ‘vos’ no Oriente boliviano, mais especificamente em Santa Cruz de la Sierra. A partir de um corpus composto por gravações de áudio de conversas de whatsapp entre pais e filhos, nosso objetivo é verificar se a forma de tratamento utilizada é compatível com a variação situacional esperada. Para a análise, baseamo-nos na Teoria da Variação Linguística (LABOV, 1966, 1972). Os resultados demonstraram que o pronome ‘vos’ tem uso corrente no Oriente boliviano, expressando não apenas familiaridade, mas também carinho e confiança.
Edição digital com propósitos pedagógicos
Authors: Almeida Elizabeth Mota Nazareth de , Barreiros Patrício Nunes
Published: January 2023

O presente artigo objetiva discutir a respeito da elaboração de plataformas digitais de acervos literários voltadas para propósitos pedagógicos. Para isso, tomou-se por parâmetro os critérios estabelecidos por Shillingsburg (1993; 1996) e Sahle (2016). Além disso, à guisa de ilustração, apresenta-se o protótipo de uma plataforma digital (em desenvolvimento) para leitura de textos literários em salas de aula de Língua Portuguesa, elaborada no âmbito do curso de doutorado do Programa de Pós-Graduação em Estudos Linguísticos da Universidade **** (****). Como corpus da pesquisa, utilizou-se os textos literários do escritor baiano Eulálio Motta, escritos na década de 1930, a saber, os causos sertanejos presentes em seu caderno de manuscritos, intitulado pelo próprio autor como Bahia Humorística e editado por Barreiros (2012; 2016). O protótipo da plataforma digital apresentada neste artigo tem como objetivo problematizar a leitura do texto literário em aulas de Língua Portuguesa, com vistas ao desenvolvimento de práticas didático-pedagógicas e elaboração de recursos didáticos impressos e digitais voltados para professores e alunos da Educação Básica. Ademais, busca-se mobilizar conhecimentos filológicos, especialmente, da crítica textual, e literários, além de abordar questões linguísticas, voltadas para a variação do português popular, e identitárias. Como resultados esperados, tenciona-se contribuir para práticas de multiletramentos, formação leitora e para o desenvolvimento de competências filológicas de professores e alunos da Educação Básica.
O Conselheiro Aires e o problema do livro em Machado de Assis: um projecto de humanidades digitais
Authors: Nunes Ariadne
Published: January 2023

O projecto "O Conselheiro Aires e o problema do livro em Machado de Assis" consiste, por um lado, na realização e disponibilização de quatro edições em formato electrónico, as edições genéticas e críticas dos dois últimos romances de que Machado de Assis é autor, Esaú e Jacó e Memorial de Aires. Por outro lado, a par destas edições, serão apresentados vários estudos que pretendem articular os dados materiais que resultam do estudo dos testemunhos com questões de poética, solicitadas pela obra de Machado. Neste texto, far-se-á uma apresentação do estado actual do projecto, mostrando como nele se tenta responder às questões colocadas pela desmaterialização destas edições, colocadas pelo meio em que o projecto se desenvolve.
Computational Analysis, in silico Functional Annotation and Expression of Recombinant mycobacterium, PE_PGRS Protein Biomarkers
Authors: Moodley-Reddy Avanthi , Chiliza Thamsanqa Emmanuel , Pooe Ofentse Jacob
Published: January 2023

Background

Over the years, there have been many advances made within the treatment and diagnosis of Mycobacterium Tuberculosis (Mtb). In recent times, the rise of drug resistance has led to higher mortality rates specifically in poorer countries. There is an urgent need for novel treatment regimens to work against Mtb. A gene family, found in Mtb, PE_PGRS proteins shows potential as a drug target in its life cycle; to prevent the activation of latent Mtb to active Mtb. In silico functional annotations of these proteins are cost-effective and avoid wasting effort on a protein with no potential.

Method

Previous studies indicated that the PE_PGRS showed potential for further research. The protein biomarkers which showed the most promise was identified as PE_PGRS17, PE_PGRS31, PE_PGRS50 and PEPGRS54. The sequences of these proteins were searched on the Mycobrowser software. Results were designed by entering these sequences into various computational algorithms. PE_PGRS17 showed characteristics of a potential vaccine candidate. Considering this result, expression profiling and purification was conducted on the recombinant PE_PGRS17 Mtb protein biomarker.

Results and Discussion

The results were calculated using various online software algorithms. Many characterizations and other aspects were predicted to understand the stability, localization, and function of these proteins. All the proteins are estimated to produce an immune response or be involved in the process of immunity. The expression condition of the recombinant PE_PGRS17 was optimised, and purification strategy achieved using E.coli as a host cell. These findings make these proteins, specifically PE_PGRS17, popular for further scientific study.

Conclusion

The predicted structures, protein-protein interaction and antigenic properties of the proteins estimate whether the protein can be used for further studies specifically as drug/vaccine targets. Ultimately PE_PGRS17 is seen as the most stable according to its structure and it holds more promise as a key factor to tuberculosis studies.
Borderline Personality Disorder In Pandemic Situation In Indonesia
Authors: Wibhowo Christin , Sanjaya Ridwan
Published: January 2023

Background

Individuals with borderline personality disorder (BPD) feel more stressed than others during the pandemic. Several researchers conducted from the West have concluded that the factors causing BPD consist of neurobiology, childhood trauma, attachment coping and social support. These results were different from the research conducted in Indonesia. Therefore, it’s necessary to re-examine the factors causing BPD as knowing the causative factors of BPD is very important for prevention.

Objectives

This research had two stages: (1) Mapping the factors causing BPD (2) Knowing the proactive coping used by participants

Method

Data collection in Study 1 used four scales: BPD scale, Childhood Adversity, Proactive Coping, and Social Support. There were 180 participants in this study. Hypothetical analysis was performed with Structural Equation Modeling (SEM) .

Online interviews were conducted in Study 2 with six participants who were previously known to have BPD based on the results of the BPD scale

Result

Study 1: Childhood adversity, social support, and proactive coping play a role in BPD. However, not all factors play a direct role in BPD. Proactive coping (PC) had a direct role in BPD. Study 2: The participants do not use proactive coping but use defense mechanisms, such as repression, regression and denial. They tend to be more depressed so they don’t use proactive coping as usual.

Conclusion

Childhood adversity, social support, and proactive coping play a role in BPD. However, only PC had a direct role. The better the PC owned, the fewer BPD criteria individuals have. The coping strategies participants carried out before the pandemic were different from those applied during the pandemic.
The quality of Indonesian teachers in the digital era: A meta-analysis
Authors: Prihono Eko Wahyunanto , Retnawati Heri , Lapele Fitria , Waluyo Wisnu Budi
Published: January 2023

The objective of the study is to determine the influence of determinant factors on teacher quality in Indonesia in the digital era in kindergarten, elementary, junior high, and high school units. It was a quantitative research with a correlation meta-analysis approach. The data was secondary data collected from various research results in Indonesia on the scholar.google.com page. The results of the study were published from 2012 to 2022. Data analysis used JASP software to estimate aggregates, draw plot Forrest, and publication bias. The aggregates were estimated through correlation scores with fixed effect models. The results showed that the funnel plot 104 study had a sample size that varied with the asymmetric distribution. Therefore, the results of the study were free from potential publication bias. It was reinforced by the forest plot display using the Trim and Fill method as well as the summary effect display results. Thus, the level of information validity based on the fixed-effect model of factors that affect the quality of teachers in the digital era in Indonesia was valid.
Evaluating the Effects of the Supportive Parenting App on Infant Developmental Outcomes: Longitudinal Study
Authors: Shorey Shefaly , Chong Yap Seng , Shi Luming , Chua Jing Shi ,   Thilagamangai, Mathews Jancy , Lim Siew Hoon , Du Ruochen , Chan Yiong Huak , Tan Thiam Chye , Chee Cornelia , Law Evelyn
Published: January 2023

Background

Previous studies have investigated the various effects of parenting on infant developmental outcomes. In particular, parental stress and social support have been found to significantly affect the growth of the newborn. Although many parents today use mobile apps to obtain more support in parenting and perinatal care, few studies have examined how these apps could affect infant development.

Objective

This study aimed to examine the effectiveness of the Supportive Parenting App (SPA) in improving infant developmental outcomes during the perinatal period.

Methods

This study adopted a 2-group parallel prospective longitudinal design and recruited 200 infants and their parents (N=400 mothers and fathers). The parents were recruited at 24 weeks of gestation for a randomized controlled trial conducted from February 2020 to July 2022. They were randomly allocated to either the intervention or control group. The infant outcome measures included cognition, language, motor skills, and social-emotional development. Data were collected from the infants when they were aged 2, 4, 6, 9, and 12 months. Linear and modified Poisson regressions were used to analyze the data to examine between- and within-group changes.

Results

At 9 and 12 months post partum, the infants in the intervention group were found to have better communication and language skills than those in the control group. An analysis of motor development revealed that a larger proportion of the infants in the control group fell under the at-risk category, where they scored approximately 2 SDs below the normative scores. The control group infants scored higher on the problem solving domain at 6 months post partum. However, at 12 months postpartum, the infants in the intervention group performed better on cognitive tasks than those in the control group. Despite not being statistically significant, the intervention group infants were found to have consistently scored better on the social components of the questionnaires than the control group infants.

Conclusions

Overall, the infants whose parents had received the SPA intervention tended to fare better in most developmental outcome measures than those whose parents had received standard care only. The findings of this study suggest that the SPA intervention exerted positive effects on the communication, cognition, motor, and socioemotional development of the infants. Further research is needed to improve the content and support provided by the intervention to maximize the benefits gained by infants and their parents.

Trial Registration

ClinicalTrials.gov NCT04706442; https://clinicaltrials.gov/ct2/show/NCT04706442
Validity and reliability study of Diabetes Fatalism Scale inTurkish patients with type 2 diabetes
Authors: Kavuran E. , Edege L.E. , Yildiz E.
Published: January 2023

Background. Turkey is one of the countries with the highest prevalence of diabetes in Europe, with about one in every seven adults diagnosed with diabetes mellitus. By 2035, Turkey will have the highest number of people with type 2 diabetes in Europe, at almost 12 million. Mortality rates have increased with the increasing prevalence of type 2 diabetes, especially in the younger population, such that half of the deaths come from those under sixty. The beliefs and mental state of patients with chronic illnesses like diabetes can affect disease outcomes and the patients’ self-management. Self-care and diabetes medications are important components in improving the disease outcome, though many studies have shown that these activities can be negatively related to fatalism about the disease state. The aim of this study was to investigate the reliability and validity of the Turkish version of the Diabetes Fatalism Scale (DFS), which was developed by Dr. Leonard Egede. Materials and methods. This was a methodological study. The scales were administered to a total of 139 patients with type 2 diabetes. The content and construct validity of the scale were assessed. The construct validity was evaluated using confirmatory factor analysis, and the reliability was assessed in terms of internal consistency. Results. In terms of the population tested, 54.7% of the participants were men, 73.4% were married, 54% had one additional disease other than diabetes, 18% were high school graduates, the mean age was 50.20±16.82 years, the average duration of diabetes was 19.31±14.25 years, and mean glycated hemoglobin level was 7.06±0.65%. It was found that the Kaiser-Meyer-Olkin (KMO) measure of sampling-size adequacy was 0.770, indicating an adequate size, and the chi-square value was 1078.402. When the fifth item was excluded from the study and the analysis was repeated, the KMO coefficient was 0.802 and the chi-square value was 1020.244, p=0.000. The Cronbach’s alpha value reached 0.806, indicating a good internal consistency. The Cronbach’s alpha values of the other subscales also seemed to be at a very good level. Conclusions. Our study showed that the DFS is a valid and reliable scale for the Turkish society. DFS-T is a suitable scale for health professionals to use to assess diabetes fatalism in adults with diabetes in Turkey.
NONWOVEN DEVELOPMENT AND CHARACTERIZATION PRODUCED FROM CIGARETTE BUTTS
Authors: Vielmo Ana Silvia de Lima , Rodrigues Ailton Borges , Tomassoni Fabiola , Hassemer Maria Eliza Nagel
Published: January 2023

Abstract
The aim of this study was to develop and evaluate the performance of a nonwoven (NT) with cellulosic material from cigarette butts. The NT used as a filtering medium had a diameter of 7 cm, height of 24 cm, a surface area of 528 cm2 and a total volume of 692 cm3. The NT was applied for the filtration of water from a pond. To evaluate NT performance, NT characterization, grammage, absorption capacity and permeability analyzes were performed. The results showed that NT was characterized as a microporous material and presented a good absorption performance (values in the order of 4.01 g g-1 to 4.99 g g-1), weight of 115 g m-2, permeability between 3.787 L m-² h-1 and 3.422 L m-² h-1. The NT developed showed potential for use as a filtering medium for the surface water pre-treatment. In addition to helping to reduce the negative environmental impacts caused by the residues of cigarette butts present in the environment.
MINIMIZAÇÃO DOS IMPACTOS AMBIENTAIS CAUSADOS POR PEÇAS DO VESTUÁRIO DESCARTADAS PÓS FABRICAÇÃO: UMA PROPOSTA DE MODELO DE NEGÓCIO PARA O POLO CONFECCIONISTA
Authors: Andrade Lucília Lemos de , Oliveira Luciana Rezende Alves de
Published: January 2023

A produção acelerada de peças do vestuário tornou-se um problema constante no mundo atual, principalmente pela geração de resíduos sólidos provenientes tanto do processo produtivo, como também, pelo descarte inadequado dessas peças pós-produção. No município de Divinópolis, reconhecido pela Lei Estadual 22.895/18, como o principal polo confeccionista do estado de Minas Gerais, essa situação não é diferente. Neste sentido, um dos objetivos deste estudo foi analisar a quantidade de peças produzidas e não vendidas pelas confecções do vestuário deste município. Para cumprir com o objetivo proposto foi utilizado um questionário para coleta de dados. Os resultados indicaram uma estimativa de 100 milhões de peças do vestuário em saldos ao ano. Dessa maneira, propõe-se a minimização dos impactos ambientais causados pelo descarte precoce de tais peças por meio de um modelo de negócio: a implantação de uma loja outlet multimarcas para comercializar, exclusivamente, produtos em saldos de empresas do polo confeccionista. Em busca de proporcionar uma vida secundária aos artigos de moda, além de conservar os recursos naturais contidos nos produtos e proporcionar uma destinação adequada conforme a Lei nº 12.305/10 (PNRS), espera-se com este estudo, contribuir com o desenvolvimento econômico das indústrias de confecção do vestuário e com a minimização dos impactos ambientais causados pelo excesso de artigos do vestuário enviados diretamente para aterros sanitários.