bluuebunny/crossref_metadata_2025 huggingface dataset:
Constitutional justiciary (procedural) rights: towards identifying and understanding the phenomenon
Authors: Sokolov T. V.
Published: January 2025

Subject. The article is devoted to the study of the existence of an independent group of human rights – human rights in the sphere of justice, also called constitutional justiciary rights. These rights are enshrined in the constitutional acts of modern states and guaranteed at the international legal level in a number of universal instruments and regional conventions on the protection of human rights. The consolidation and implementation of these rights is intended to ensure, with the help of judicial procedures, the reality of the constitutionalism regime and social justice in specific cases considered by the courts.Purpose of the study. The article aims to prove the existence of constitutional judicial rights as a category of current law.Methodology. The article relies on the wide application of comparative legal, historical legal and formal dogmatic methods. The historical legal method made it possible to trace the consolidation of judicial rights in the constitutions of England, the USA, France, Italy and Germany in the 18th-19th centuries. Using the comparative legal method, the constitutions of the modern world were studied and a quantitative rating of the prevalence of these rights was compiled. The formal dogmatic method made it possible to define approaches to the theoretical study of this group of human rights.Conclusions. An independent group of human rights – justiciary rights – exists and is subject to allocation (recognition) as part of the general legal status of an individual. Such rights is defined as human rights realized in the field of justice.
On certain aspects of international and foreign economic relations of local self-government bodies
Authors: Dityatkovsky M. Yu.
Published: January 2025

The subject. This article has been prepared in order to analyze federal and regional legislation in the field of regulation of international and foreign economic relations of local governments, as well as to prepare proposals for its improvement. This article examines the main issues related to the definition of the concept of "international and foreign economic relations of local self-government bodies" and indicates its signs; analyzes the powers of bodies of three levels of public authority in the field of international and foreign economic relations of local self-government bodies and problematic issues related to their implementation; analyzes the normative legal acts necessary for adoption at the level of the subjects of the Russian Federation and municipalities in this area.Main results. International and foreign economic relations of local self-government bodies should be understood as the relations carried out by local self-government bodies in order to resolve issues of local importance and, in coordination with the state authorities of the subject of the Russian Federation, with representatives of state-territorial, administrativeterritorial and municipal formations of foreign states, with local self-government bodies of foreign states, including for the purpose of participation in activities international organizations in the field of inter-municipal cooperation.Conclusions. There are no provisions in federal legislation on the need for the Ministry of Economic Development of the Russian Federation to organize interaction with other federal executive authorities in order to effectively exercise powers in the field of international and foreign economic relations of local governments. In this regard, this gap needs additional legal regulation. There is a need to include new provisions in federal legislation defining the features of the legal status of "twin cities", as well as supplementing federal and regional organizations of inter-municipal cooperation among the subjects of international and foreign economic relations.
Causes, Management and Prevention of Orthodontic Discomfort
Authors: Alshahrani Khozam Mohammad , Alshehri Waleed Ali , Alawami Jenan Hassan , Alabbad Hawraa Mohammad , Almutairi Metib Theyab , Hawsawi Marwan Mohammed
Published: January 2025

Orthodontic discomfort is a significant concern for patients undergoing treatment, arising primarily from the application of mechanical forces that trigger an inflammatory response in the periodontal ligament and surrounding tissues. This discomfort, which often peaks within 24 to 48 hours after appliance activation, is influenced by various factors, including the magnitude of force applied, appliance design, and individual patient variability. Biomechanical forces initiate the release of inflammatory mediators, such as prostaglandins and cytokines, sensitizing nociceptors and leading to pain. Soft tissue irritation caused by brackets, wires, or aligners further exacerbates the experience of discomfort. Management strategies for orthodontic pain focus on pharmacological interventions, including nonsteroidal anti-inflammatory drugs, and alternative approaches like low-level laser therapy and vibratory devices. Behavioral interventions, such as patient education and relaxation techniques, complement these methods, addressing the psychological aspects of pain perception. Advances in orthodontic appliances, including self-ligating brackets and aligners, have improved patient comfort by minimizing friction and optimizing force distribution. Preventive approaches aim to reduce the onset of discomfort through careful treatment planning, improved appliance design, and enhanced oral hygiene protocols. Gradual force application, digital treatment planning, and customized aligners have contributed to a more patient-centered approach, reducing tissue trauma and optimizing outcomes. Emphasis on maintaining periodontal health through professional cleanings and tailored hygiene practices further mitigates secondary discomfort caused by inflammation. Understanding the multifactorial nature of orthodontic discomfort has driven innovations in treatment and prevention, enhancing the overall patient experience. The integration of advanced technologies, personalized care, and effective pain management strategies underscores the progress in reducing discomfort while achieving desired therapeutic results. Ongoing research continues to explore novel interventions to refine these approaches, ensuring a balance between clinical effectiveness and patient comfort.
Evaluation of Centrifugation Technique and the Effect of Centrifugation Condition on the Laboratory Samples
Authors: Fallatah Majed Hashem , Al Otaibi Aaied Falah , Aljohani Randa Rajallah , Ghabban Waad Jamal , Alshehri Alaa Ali
Published: January 2025

Centrifugation is a critical laboratory technique used to separate components within a mixture based on density differences. The efficiency and reliability of this process depend on the precise control of variables such as speed, time, temperature, and rotor design. Improper centrifugation settings can compromise sample integrity, leading to analytical inaccuracies. High-speed centrifugation, while effective for rapid separation, often imposes mechanical stress on samples, resulting in hemolysis or cellular damage. Time duration is equally significant, as insufficient centrifugation can cause incomplete separation, while prolonged exposure may induce thermal stress and biochemical degradation. Temperature control plays a pivotal role, particularly for temperature-sensitive biomolecules like enzymes, nucleic acids, and proteins. Unregulated temperatures during high-speed centrifugation can denature proteins and degrade nucleic acids, affecting their utility in downstream applications such as diagnostics and molecular biology. Automated centrifuges equipped with programmable cooling systems have proven effective in mitigating these risks. Centrifugation protocols require customization based on sample type. Blood, urine, and cellular samples exhibit distinct sensitivities to centrifugal force and duration, necessitating tailored approaches. Specialized techniques, such as density-gradient centrifugation, enhance separation precision for applications like exosome isolation. Recent innovations in centrifuge technology, including programmable speed ramps and advanced rotor designs, have significantly improved the reproducibility and reliability of centrifugation processes. Standardization of centrifugation protocols is essential to ensure consistency in laboratory results. Advances in centrifuge design and optimization strategies have enabled better preservation of sample integrity across diverse applications. These developments highlight the need for continuous refinement of protocols to accommodate emerging diagnostic and research requirements, ensuring high-quality outcomes in both clinical and experimental settings.
Building Effective Communication Skills for High-Stress Hospital Settings
Authors: Albaharna Aqeela Mohmmed , Aloqaili Aqeela Abdulrahman , Alshahrani Sara Saeed , Aldilbah Faten Abdullah , Aljohani Ohud Abdullah , Aljohani Khulud Abdullah
Published: January 2025

Effective communication in critical care settings is paramount for ensuring patient safety and facilitating team collaboration during high-stakes situations. However, numerous barriers impede clear and effective communication, including hierarchical dynamics, cultural and linguistic differences, fatigue, and the complexities of integrating technology. Hierarchies within healthcare systems often discourage open dialogue, particularly among junior staff who may hesitate to voice concerns. This dynamic can delay critical interventions or result in errors. Similarly, cultural diversity within multidisciplinary teams can lead to misunderstandings stemming from differences in communication styles and norms, further complicating interactions in high-pressure environments. Structured communication frameworks such as Situation, Background, Assessment, Recommendation (SBAR) standardize information exchange, ensuring clarity and reducing cognitive load during emergencies. Additionally, cultural competence training programs equip healthcare professionals with the skills to navigate linguistic and cultural challenges effectively, fostering greater cohesion within diverse teams. While technology enhances communication by enabling rapid information sharing, its misuse or failure can disrupt workflows, emphasizing the need for proper training and contingency planning. Psychological safety within teams has proven instrumental in enabling open and transparent communication. Interprofessional education and collaborative exercises promote mutual understanding and align goals across diverse professional roles. Addressing physical and environmental distractions, such as noise and interruptions in critical care units, further enhances communication effectiveness. Combining these strategies mitigates barriers, ensuring better teamwork, improved decision-making, and optimal patient outcomes in critical care settings.
Development and Validation of HPLC Method for Simultaneous Estimation of Metformin HCl with Ertugliflozin L-Pyroglutamic Acid in Tailored Formulation
Authors: Muhammad Ashraf Muhammad Ashraf , Shaista Zafar Shaista Zafar , Rustem Zairov Rustem Zairov , Sana Shaikh Sana Shaikh , Syed Moazzam Haider Syed Moazzam Haider , Nida Ali Nida Ali , Kamran Shaikh and Mohsin Ali Kamran Shaikh and Mohsin Ali
Published: January 2025

The present study introduced an innovative and quick RP-HPLC approach for simultaneous determination of Metformin HCl (MET) and Ertugliflozin L-pyroglutamamic acid (ERT). This new method is simple, accurate, precise and highly sensitive. The separation of both drugs was optimized at 40and#176;C using HPLC column (C8, 4.6 x 150mm 5 microns) and mobile phase comprising of triethylamine in sodium octane sulfonate (pH 4) : MeOH: ACN in a ratio of 45:45:10 respectively, with a flow rate of 1.0 ml /min. The specificity of method showed that there was no interference from placebo or diluent during the drugand#39;s retention period. Accuracy and linearity studies conducted at different concentrations displayed good precision and the calibration curves exhibited high correlation i.e. R2= 0.9982 and 0.9996 for ERT and MET, respectively. Precision was assessed for repeatability and intermediate precision, both delivering satisfactory results. Robustness was evaluated under different conditions, including wavelength and flow rate variations, showing acceptable results. Limits of detection (LOD) and quantification (LOQ) demonstrated good sensitivity. The accuracy and reliability of the suggested approach for the simultaneous measurement of MET and ERT are guaranteed by the analytical method validation. Comparative analysis of the bespoke new formulationand#39;s complete dissolution profile (CDP), Ertozin-M (7.5/500mg) with innovator tablet and Segluromet (7.5/500mg) was also observed at three different pH mediums (0.1 N HCl and buffer solutions of pH 4.5 and pH 6.8). This study was conducted according to International Council for Harmonization (ICH) guideline Q2(R2) on validation of analytical procedures and Q4B annex 7(R2) for Dissolution Test. The developed HPLC method was found highly suitable for combined estimation of Metformin HCl and Ertugliflozin L-pyroglutamic acid in quality control routine analysis for development of customized pharmaceutical formulations.
Xây dựng văn hóa nhà trường ở các trường mầm non huyện Long Phú, tỉnh Sóc Trăng
Authors: Hồ Thu Hằng
Published: January 2025

Việc xây dựng văn hóa trường mầm non là quá trình xây dựng các hoạt động chăm sóc, giảng dạy và giáo dục nhân cách cho trẻ một cách phù hợp, hiệu quả, đồng thời hình thành những chuẩn mực ứng xử văn minh lịch sử và thân thiện. Thông qua phương pháp khảo sát điều tra bằng phiếu hỏi gửi đến 30 cán bộ quản lý và 100 giáo viên ở các trường mầm non trên địa bàn huyện Long Phú, tỉnh Sóc Trăng, chúng tôi tiến hành phân tích và đánh giá công tác xây dựng văn hóa nhà trường tại các trường mầm non huyện Long Phú, kết quả cho thấy công tác này đã đạt được những kết quả đáng kể, với nhiều chuyển biến tích cực, góp phần quan trọng nâng cao chất lượng giáo dục ở địa phương. Tuy nhiên trong quá trình thực hiện các trường mầm non ở huyện Long Phú vẫn còn gặp phải một số hạn chế chưa được khắc phục kịp thời. Dựa trên kết quả nghiên cứu thực tiễn này, chúng tôi đề xuất các biện pháp nhằm xây dựng văn hóa nhà trường tại các trường mầm non huyện Long Phú tỉnh Sóc Trăng trong bối cảnh hiện nay góp phần nâng cao chất lượng giáo dục nói chung và chất lượng giáo dục xây dựng văn hóa nhà trường ở các trường mầm non nói riêng.
A complication of obesity: Chronic lymphedema leading to a vulval mass
Authors:   Department of Obstetrics and Gynaecology, Liverpool Hospital, Liverpool, New South Wales, Australia., Chang Cynthia
Published: January 2025

We describe the case of a 54-year-old female presenting with a large pedunculated mass arising from the labia minora. Initially suspected to be a papilloma, histopathology confirmed the mass to be benign in nature secondary to chronic lymphedema
Incidental vestibular schwannoma, personality change and LGI-1 antibody related autoimmune encephalitis - A coincidence which delayed diagnosis
Authors:   Department of Neurology, Pt BDS, PGIMS, Rohtak, India., Kumar Naveen
Published: January 2025

Autoimmune Encephalitis (AE) is an emerging autoimmune inflammatory neurological disorder in which antibodies are directed against intracellular or cell surface neuronal antigens in Central Nervous System (CNS). Autoimmune Encephalitis (AE)
A case of granulomatosis with polyangiitis misdiagnosed as severe asthma: The key role of spirometry
Authors:   Department of Translational Medical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy., Calabrese Cecilia
Published: January 2025

Granulomatosis with Polyangiitis (GPA) is a granulomatous, necrotizing small-vessel vasculitis associated with the presence of Antineutrophil Cytoplasmic Antibodies (ANCA). In more than eighty percent of GPA patients ANCA have a Cytoplasmatic Pattern
Laryngeal fracture after sneezing
Authors:   Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Giger Roland
Published: January 2025

A healthy 61-year-old man sought emergency care after experiencing neck swelling (Figure 1), throat discomfort, and hoarseness, which developed gradually over two days following a forceful and blocked sneeze. He reported a painful sensation of rupture in his anterior neck. Neck palpation
Drooling toddler
Authors:   Boonshoft School of Medicine, Wright State University, Dayton, OH 45324, USA., Hurst Haley
Published: January 2025

A 2-year-old female was brought to the emergency department due to decreased oral intake and drooling that began earlier the same day.
Kaposis Sarcoma in a patient with rheumatoid arthritis treated with tofacitinib
Authors:   Department of Rheumatology, Hospital Universitario Infanta Sofia, Universidad Europea de Madrid, Madrid, Spain., S Munoz- Fernandez
Published: January 2025

Kaposis Sarcoma (KS) is a multicentric antiproliferative tumor of mesenchymal origin with 4 variants, namely, classic, African, AIDS-associated, and iatrogenic. The iatrogenic variant has been associated with immunosuppressive treatment [1].
Vascular access complications in a preterm infant: Umbilical venous catheter fracture and cardiac tamponade
Authors:   Department of Pediatrics and Neonatology, Mongi Slim Hospital, La Marsa, Tunis, Tunisia., Marmech Emna
Published: January 2025

Vascular access in preterm infants is a critical yet challenging aspect of neonatal care, often fraught with complications. We report the case of a 30-week gestational age female infant who experienced two consecutive and life-threatening vascular access complications:
Early dysfunction of mitral bioprostheses: A challenge in identifying the underlying mechanisms
Authors:   Department of Internal Medicine, School of Medicine of the Federal University of Minas Gerais, Av, Professor Alfredo Balena, 190, Santa Efigenia, 30130 100 - Belo Horizonte, MG, Brazil., MC Pereira Nunes
Published: January 2025

Bioprosthetic Valve Dysfunction (BVD) and Bioprosthetic Valve Failure (BVF) can be divided into structural valve deterioration, non-structural valve dysfunction, thrombus and endocarditis. BVF is a clinical consequence of BVD, leading to both morphological and hemodynamic deterioration, often requiring reintervention.
THE EFFICIENCY OF IRRIGATION IN CORN CULTIVATION UNDER THE IMPACT OF CLIMATE CHANGE IN SOUTHEASTERN ROMANIA: ADAPTATION AND OPTIMIZATION. A REVIEW
Authors: NIȚU Oana Alina , IVAN Elena Ştefania , JERCA Ionuț Ovidiu
Published: January 2025

Climate change significantly affects corn cultivation in Romania, leading to an increase in the frequency of droughts and heatwaves, as well as changes in precipitation patterns. In this context, irrigation becomes a crucial solution for maintaining production stability and reducing the risk of agricultural losses.This study analyzes the impact of irrigation systems on corn cultivation, highlighting effective methods of water management under water stress conditions. Different irrigation techniques, such as drip and sprinkler irrigation, were evaluated to optimize water application during the critical stages of plant development.Additionally, the research addresses the genetic adaptation of corn to new climate conditions through the use of drought- and heat-resistant hybrids, which can sustain productivity even during periods of extreme stress.Through climate and agricultural models, we estimated the long-term impact of climate change on corn yields, proposing adaptation scenarios based on sustainable practices, crop rotation, and technological innovations. The results show that optimized irrigation and the selection of climate-adapted hybrids can significantly reduce production losses and support Romanian agriculture in the face of challenges generated by climate change. Our study emphasizes the importance of implementing long-term strategies to maintain sustainable corn production and presents viable solutions for Romanian farmers in the context of current and future climate changes.
Đánh giá kết quả soi buồng tử cung cắt polyp ở bệnh nhân vô sinh tại Bệnh viện Phụ sản Trung ương
Authors: Du Vũ Văn , Tuấn Hoàng Nghĩa , Hương Lê Thị Ngọc , Tốt Đặng Văn , Hằng Nguyễn Thị
Published: January 2025

Nghiên cứu nhằm mô tả đặc điểm lâm sàng và cận lâm sàng của polyp niêm mạc buồng tử cung ở bệnh nhân vô sinh và nhận xét kết quả xử trí polyp niêm mạc buồng tử cung bằng phẫu thuật nội soi ở nhóm bệnh nhân này tại Bệnh viện Phụ sản Trung ương từ tháng 8/2022 đến tháng 7/2023. Cỡ mẫu gồm 194 bệnh nhân với độ tuổi trung bình 31,6 ± 5,8 tuổi, phần lớn bệnh nhân chưa có con. Triệu chứng lâm sàng chủ yếu là rong kinh rong huyết. Kích thước của polyp niêm mạc tử cung trên siêu âm trung bình là 10,8 ± 5,3mm, đa số dưới 20mm. Nhóm bệnh nhân có kích thước polyp từ ≥ 10mm có tỷ lệ ra máu âm đạo bất thường cao gấp 2,32 lần so với nhóm có kích thước polyp < 10mm (OR = 2,32; KTC 95%: 1,11 – 4,92; p < 0,05). Đa số phương xử trí polyp niêm mạc BTC trong nghiên cứu là cắt bằng dụng cụ nội soi, chiếm tỷ lệ 96,9%. Có 178 bệnh nhân vô sinh được kết hợp nội soi ổ bụng chẩn đoán mà không có xử trí khác (91,8%). Sau phẫu thuật 1 năm, có 55 trường có thai tự nhiên, chiếm tỷ lệ 28,4%. Có 64 trường hợp có thai nhờ hỗ trợ sinh sản, chiếm tỷ lệ 34,0%.
Vai trò của PET-CT trong chẩn đoán giai đoạn bệnh ung thư vòm mũi họng tại Bệnh viện K
Authors: Đăng Nguyễn Văn , Thắng Phạm Văn
Published: January 2025

Ung thư vòm mũi họng là bệnh lý ác tính thường gặp vùng đầu cổ. Nghiên cứu cắt ngang trên 73 người bệnh ung thư biểu mô vòm mũi họng (týp 3 - WHO 2017) từ tháng 06/2023 đến tháng 06/2024 tại Bệnh viện K nhằm đánh giá vai trò của PET-CT trong chẩn đoán giai đoạn bệnh của nhóm nghiên cứu. Kết quả: Giá trị hấp thu chuẩn (SUV max) trung bình tại u nguyên phát là 16,6, tại hạch cổ là 13,1. Giá trị SUV max trung bình tại u nguyên phát và hạch cổ tăng dần theo giai đoạn T, N, sự khác biệt có ý nghĩa thống kê (p < 0,05). So với các phương tiện chẩn đoán hình ảnh khác (MRI, CLVT, xạ hình xương, siêu âm), PET-CT làm thay đổi giai đoạn T ở 24,7% bệnh nhân, giai đoạn N ở 17,8% bệnh nhân và phát hiện ra 6,8% bệnh nhân có di căn xa mà không được phát hiện bởi các phương tiện chẩn đoán hình ảnh (CĐHA) khác. PET-CT làm thay đổi giai đoạn chung ở 26% bệnh nhân nghiên cứu.
MicroRNA-21 và sẹo teo sau mụn trứng cá: Nghiên cứu cắt ngang trên 70 bệnh nhân
Authors: Nguyên Nguyễn Trần Thảo , Trai Nguyễn Ngọc , My Vũ Diễm , Phương Huỳnh Anh , Trở Châu Văn
Published: January 2025

Sẹo teo là một di chứng phổ biến sau mụn trứng cá, ảnh hưởng lớn đến thẩm mỹ và chất lượng cuộc sống của người mắc. Cơ chế chính xác hình thành sẹo vẫn chưa sáng tỏ. Gần đây, trong bối cảnh sinh học phân tử phát triển, microRNA-21 được nhận diện là một yếu tố tiềm năng có liên quan mật thiết đến quá trình hình thành sẹo teo. Nhằm đánh giá mức độ biểu hiện microRNA-21 trong huyết tương và so sánh giữa nhóm bệnh nhân có và không có sẹo teo, chúng tôi tiến hành nghiên cứu mô tả cắt ngang trên 70 bệnh nhân mụn trứng cá tại Bệnh viện Da liễu Thành phố Hồ Chí Minh từ tháng 04/2024 đến tháng 09/2024. Nhóm nghiên cứu gồm 35 bệnh nhân có sẹo teo (nhóm A) và 35 bệnh nhân không có sẹo (nhóm B). Kết quả cho thấy mức độ biểu hiện microRNA-21 trung bình ở bệnh nhân mụn là 2,758 ± 5,01. Đặc biệt, nhóm A có mức biểu hiện cao hơn đáng kể (3,773 ± 6,733) so với nhóm B (1,742 ± 1,864), sự khác biệt có ý nghĩa thống kê (p = 0,01). Mức độ biểu hiện microRNA-21 không phụ thuộc vào độ nặng của mụn nhưng lại liên quan đến mức độ sẹo, nhóm bệnh nhân có sẹo nhẹ có mức độ biểu hiện cao nhất (p = 0,045).
Kết quả áp dụng chiến lược 2X trong hoạt động phát hiện chủ động bệnh lao tại cộng đồng tỉnh Thái Nguyên giai đoạn 2020 - 2023
Authors: Ngân Dương Thị Kim , Xuân Lê Thị Thanh , Quân Phạm Thị
Published: January 2025

Nghiên cứu mô tả cắt ngang với đánh giá kết quả áp dụng chiến lược 2X trong hoạt động phát hiện chủ động bệnh lao tại cộng đồng tỉnh Thái Nguyên giai đoạn 2020 - 2023. Số liệu được thu thập từ 43.139 người dân tham gia khám sàng lọc phát hiện bệnh lao bằng chiến lược 2X từ 2020 - 2023 tại các địa phương được lựa chọn thực hiện chương trình. Kết quả cho thấy tỷ lệ người dân được khám sàng lọc chủ động bệnh lao theo chiến lược 2X chiếm 0,8% dân số, cao nhất là năm 2020 (chiếm tỉ lệ 1,5% dân số) và thấp nhất là năm 2023 (chiếm tỉ lệ 0,3% dân số). Tỷ lệ người dân tham gia khám sàng lọc chủ động bệnh lao bằng chiến lược 2X được chỉ định làm xét nghiệm Xpert MTB/RIF là 1,6%. Tỷ lệ số người chẩn đoán mắc lao trong tổng số những người khám sàng lọc là 0,6%. Kết quả của chiến lược 2X góp phần vào việc tăng cường phát hiện bệnh nhân lao, đưa người bệnh vào điều trị sớm, cắt đứt nguồn lây trong cộng đồng. Chương trình chống lao tỉnh Thái Nguyên cần đẩy mạnh tổ chức các chiến dịch sàng lọc định kỳ hơn nữa để tăng tỷ lệ hiện chủ động bệnh lao trong cộng đồng.
Sự hài lòng của phụ huynh có con từ 4 - 8 tuổi được điều trị phục hồi thân răng cối sữa bằng chụp Bioflx tại Bệnh viện Răng Hàm Mặt Thành phố Hồ Chí Minh
Authors: Tín Bùi Trung , Quân Trần Duy , Phương Nguyễn Thị Mai , Ngọc Võ Trương Như
Published: January 2025

Một nghiên cứu cắt ngang được tiến hành trên 17 phụ huynh có con từ 4 - 8 tuổi được điều trị phục hồi thân răng cối sữa bằng chụp Bioflx tại Bệnh viện Răng Hàm Mặt Thành phố Hồ Chí Minh từ tháng 10/2023 đến tháng 6/2024. Tuổi trung bình của người tham gia nghiên cứu là 33,2 ± 4,8 tuổi và giới tính đa số là nữ (chiếm 70,6%). Đo lường sự hài lòng của phụ huynh với quá trình điều trị cho con của họ thông qua bộ câu hỏi đánh giá hài lòng nha khoa DSQ phiên bản tiếng Việt với 4 khía cạnh bao gồm “sự thuận tiện của quá trình điều trị”, “chất lượng điều trị”, “kiểm soát đau cho trẻ” và “chi phí điều trị”. Kết quả cho thấy 100% phụ huynh đã hài lòng với quá trình điều trị phục hồi bằng chụp Bioflx với tổng điểm ghi nhận được là 108,9 ± 5,6 điểm. Phục hồi thân răng cối sữa bằng chụp Bioflx là một giải pháp mới, mang lại sự hài lòng rất cao từ phía phụ huynh của trẻ tại thời điểm 3 tháng sau điều trị.
Báo cáo hàng loạt ca: Đặc điểm những trường hợp thai ngoài tử cung vỡ mất máu ≥ 300ml
Authors: Tuấn Nguyễn Quốc , Thịnh Lê Hồng , Hoàng Nguyễn Thái , Thảo Lê Trần Thanh , Mỹ Nguyễn Xuân
Published: January 2025

Nghiên cứu đặc điểm và mô tả kết quả điều trị của những trường hợp thai ngoài tử cung vỡ có lượng máu mất ≥ 300ml. Đối tượng nghiên cứu là những trường hợp bị thai ngoài tử cung vỡ có lượng máu mất ≥ 300ml. Kết quả đa số trong độ tuổi sinh sản tốt nhất là từ 20 - 35 tuổi (40 trường hợp, chiếm tỷ lệ 74,1%). Có 5 bệnh nhân ≥ 40 tuổi (chiếm tỉ lệ 9,3%); tỷ lệ bệnh nhân làm nghề tự do bị thai ngoài tử cung vỡ cao gấp 3 lần bệnh nhân làm theo giờ hành chánh (79,6% so với 20,4%); tỷ lệ bệnh nhân bị thai ngoài tử cung vỡ tham gia mạng xã hội nhiều gấp 3 lần nhóm bệnh nhân không tham gia mạng xã hội (75,9% so với 24,1%); Tỷ lệ phẫu thuật nội soi cao hơn mở bụng (74,1% so với 25,9%); có 9 trường hợp cần phải truyền máu (16,8 %), lượng máu truyền lớn nhất là 3 đơn vị.
Chi phí trực tiếp cho y tế của người bệnh phổi tắc nghẽn mạn tính mức độ trung bình đến rất nặng: Phân tích dữ liệu lớn từ Bảo hiểm Y tế Việt Nam năm 2020
Authors: Kiệt Phạm Huy Tuấn , Nhiên Nguyễn Phan Thùy
Published: January 2025

Nghiên cứu phân tích chi phí điều trị trực tiếp cho y tế của bệnh phổi tắc nghẽn mạn tính (BPTNMT) ở mức độ trung bình đến rất nặng theo phân loại GOLD 2023 (Global Initiative for Chronic Obstructive Lung Disease). Đây là nghiên cứu mô tả cắt ngang, hồi cứu tất cả các lượt khám chữa bệnh của người bệnh BPTNMT từ cơ sở dữ liệu Bảo hiểm Y tế trong năm 2020 để xác định chi phí trực tiếp cho y tế của người bệnh phân loại theo GOLD. Phân tích cho thấy tổng cộng có 328.634 người mắc BPTNMT trong năm 2020, trong đó tỷ lệ người bệnh từ mức độ trung bình đến rất nặng (GOLD 2-4) chiếm tỷ lệ 78,12% - trong đó các mức độ GOLD 2, 3 và 4 lần lượt là 59,0%; 37,4% và 3,6%. Chi phí trung bình/ người/ năm theo phân loại GOLD 2, 3 và 4 được BHYT chi trả sau khi quy đổi theo CPI về 2023 lần lượt là 2,2; 6,3; và 6,6 triệu đồng. Như vậy, phần lớn người bệnh BPTNMT có mức độ trung bình đến rất nặng theo GOLD và chi phí điều trị tăng theo mức độ. Việc kiểm soát tốt BPTNMT ở các giai đoạn sớm tránh dẫn đến bệnh tiến triển sang giai đoạn muộn có ý nghĩa quan trọng trong việc giảm gánh nặng bệnh tật do BPTNMT gây ra tại Việt Nam.
Sốc nhiễm khuẩn tại Bệnh viện Hoàn Mỹ Cửu Long: Kết quả điều trị và một số yếu tố tiên lượng
Authors: Luân Nguyễn Thành , Trang Nguyễn Việt Thu
Published: January 2025

Mục tiêu khảo sát kết quả điều trị và một số yếu tố tiên lượng tử vong trong sốc nhiễm khuẩn tại Bệnh viện Hoàn Mỹ Cửu Long. Nghiên cứu mô tả loạt ca bệnh tiến cứu với 82 bệnh nhân sốc nhiễm khuẩn nhập khoa Hồi sức tích cực, từ 5/2023 đến 5/2024, độ tuổi trung bình 68,6 ± 11,6). Thời điểm chẩn đoán, trung vị lactate 4,64 (KTPV: 2,86 - 7,37) mmol/L, trung vị SOFA 8,0 (KTPV: 6,0 - 11,0) điểm. Tỷ lệ tử vong nội viện là 24,4%. Nồng độ lactate máu và điểm SOFA giảm dần theo thời gian điều trị ở nhóm sống, nhưng ít biến đổi ở nhóm tử vong. Phân tích đa biến cho thấy tuổi (OR = 1,09; KTC 95%: 1,02 - 1,17; p = 0,017), điểm SOFA thời điểm chẩn đoán (OR = 1,46; KTC 95%: 1,09 - 1,96; p = 0,012), thanh thải lactate máu thời điểm 24 giờ (OR = 0,98; KTC 95%: 0,97 - 1,00; p = 0,030) là những yếu tố liên quan đến tử vong nội viện. Tỷ lệ tử vong của bệnh nhân sốc nhiễm khuẩn tại Bệnh viện Hoàn Mỹ Cửu Long năm 2023 - 2024 tương đối thấp với các chỉ số mức độ nặng (SOFA, lactate máu) không cao. Tuổi, điểm SOFA thời điểm chẩn đoán, độ thanh thải lactate máu 24 giờ là một số yếu tố tiên lượng tử vong sốc nhiễm khuẩn trong phân tích đa biến.
Tác dụng của siêu âm điều trị kết hợp kinh cân liệu pháp trên bệnh nhân hội chứng cổ vai cánh tay
Authors: Hải Phan Thanh , Ngọc Nguyễn Kim , Hà Nguyễn Thị Thu , Nghĩa Dương Trọng
Published: January 2025

Nghiên cứu được tiến hành nhằm đánh giá tác dụng giảm đau và cải thiện chức năng sinh hoạt hàng ngày của siêu âm điều trị kết hợp điện châm và xoa bóp bấm huyệt theo kinh cân liệu pháp trên bệnh nhân hội chứng cổ vai cánh tay do thoái hóa cột sống cổ. Phương pháp nghiên cứu can thiệp lâm sàng, so sánh trước và sau điều trị, có đối chứng. 60 bệnh nhân được chia 2 nhóm, nhóm nghiên cứu được điều trị bằng siêu âm điều trị kết hợp kinh cân liệu pháp, nhóm chứng được điều trị bằng kinh cân liệu pháp đơn thuần. Kết quả sau 21 ngày điều trị, nhóm nghiên cứu có điểm đau VAS trung bình giảm từ 4,57 ± 1,19 (điểm) xuống 1,03 ± 0,85 (điểm), thấp hơn nhóm chứng có ý nghĩa thống kê (p < 0,05); nhóm nghiên cứu cải thiện chức năng sinh hoạt hàng ngày theo thang điểm NDI nhiều hơn nhóm chứng với p < 0,05. Như vậy, siêu âm điều trị kết hợp điện châm và xoa bóp bấm huyệt theo kinh cân liệu pháp có tác dụng giảm đau và cải thiện chức năng sinh hoạt hàng ngày trên bệnh nhân có hội chứng cổ vai cánh tay do thoái hóa cột sống cổ.
A REVIEW ON UTILIZATION & MARKET APPROACH FOR COMPOST
Authors: Chhatre Monika , Lakhani Chandani , S.Y. Bodkhe
Published: January 2025

The effective management of solid wastes is vital for safeguarding public health and maintaining environmental quality. In developing countries, the majority of solid waste is disposed of in open dumps indiscriminately, causing significant environmental risks. Composting provides a practical and cost-effective solution for the management and treatment of organic wastes. This review paper provides an in-depth analysis of markets for compost and the various limitations associated with its use. Different gas emissions are generated as well during the composting of organic leftovers. the recording of gaseous emissions throughout the characterization process. The report addresses as well capacity processes. In the study, a few technical variables that are helpful when designing the compost unit are additionally discussed. The paper provides a thorough analysis of the costs associated with various composting technologies. In addition, this paper presents data on energy consumption in composting processes. Furthermore, it also provides details on composting principles, processes, energy consumption, and the various factors that influence composting.
Influence of Different Soil Amendments on the Growth Performance of Lipote (Syzygium polycephaloides (C.B. Rob.) Merr) Seedlings
Authors: P. Bautista Jan Orville , D. Buhong Novelyn
Published: January 2025

Native fruit trees are valuable because they provide local communities with food, nourishment, and source of livelihood but only few are being utilized. Syzygium polycephaloides locally known as lipote in the Philippines is a native tree species from the family Myrtaceae. Hence, this study was conducted to determine the percent survival and growth response of this species treated with different soil amendments. There were four treatments namely: control or garden soil alone (Treatment 1), mixture of garden soil and cow dung (Treatment 2), mixture of garden soil and chicken manure (Treatment 3), and mixture of garden soil and sawdust (Treatment 4). Results revealed that height gained, leaf count, root collar diameter, and root length were significantly different among treatments. S.polycephaloides seedlings had 100% percent survival except for seedlings applied with chicken manure. Meanwhile, seedlings treated with cow dung gave significant growth response compared to other treatments. As a result, it can be suggested as a soil amendment for lipote seedlings in the nursery given the same set of condition employed in this investigation.
Effect of Different Salinity on Survival and Growth of Amur Carp, Cyprinus Carpio Haematopterus (Linnaeus, 1758)
Authors: Nikki  , Ahalavat Shikha , Singh Paramveer , Mehta Pragya
Published: January 2025

In inland saline water in an arid/semi-arid region of Haryana, India, a 60-day experiment was carried out to evaluate the growth and survival response of Amur carp, Cyprinus carpio haematopterus (Linnaeus, 1758). Following acclimatization, 300 fingerlings with an average weight of 8.38 0.04 g were evenly distributed into 5 treatment groups (salinities: control C 0 ppt; T1 3 ppt; T2 6 ppt; T3 9 ppt and T5 12 ppt) with 3 replicates in 500 L FRP tanks. Throughout the investigation, 9 ppt and 12 ppt were found to have changed behaviors such as swimming activity and appetite. While physio-chemical characteristics of the water, such as pH, temperature, and dissolved oxygen (DO), did not differ significantly over the course of the experiment, others, such as ammonia, nitrite, total dissolved solids (TDS), and conductivity, did. The highest survival rate was obtained in T1, whereas T2, T3, and T4 all showed a declining tendency as salinity increased. Fish growth (ADG, SGR, and TWG) considerably decreases (P0.05) from control to T4, although FCR significantly increases with salinity. According to the findings, Amur carp (Cyprinus carpio haematopterus) may be cultivated at a density of 6 ppt, and most likely as low as 5 ppt.
Impact of organic nutrient inputs on growth and yield attribute of brinjal (Solanum melongena L.) cv. “Pusa Shyamala”
Authors: Shivran Uttam , Lakhawat S.S. , Bairwa H.L. , Yadav K.K. , Saharan Vinod , B. Upadhyay  , Verma Arvind
Published: January 2025

The present study was conducted to examine the impact of organic nutrient inputs on the growth and yield attributes of brinjal at the Horticulture Farm, Rajasthan College of Agriculture, MPUAT, Udaipur during the rainy seasons of 2022-23 and 2023-24. Thirteen different treatments, consisting of various combinations of organic nutrient inputs, were tested in a randomized block design (RBD) with three replications. The recommended dose of nitrogen (RDN) used was 100 kg per hectare. The results indicated that among the thirteen treatments evaluated, the application of ½ RDN through FYM (Farm Yard Manure) combined with ½ RDN through poultry manure and supplemented with 10% Vermiwash (sprayed at 30 and 60 days after transplanting) resulted in the highest number of flowers, leaf area index, fruit weight, and yield per plot compared to the other treatments. The lowest values for these parameters were observed in the control treatment, where no manure was applied.
Study on the Effect of Some Biocontrol Agent in Grey Blight of Tea
Authors: Chanda Dhritiman , Khatun Mursida
Published: January 2025

Tea plantation is covered by 434,000 hectares of land, which is further divided into two distinct regions - the North Indian tea belt and the South Indian tea belt. North-East India produces 75% of the total Indian tea. Present study is carried out to understand the various agro-climatic conditions of Bramhaputra valley like temperature, humidity, rainfall etc which are responsible for occurrence of various diseases in tea plant. The bio control agents are eco-friendly to control the plant diseases with aim of developing a sustainable system in agriculture. It involves in the mechanism of interaction among the antagonists and pathogens, which aid in selection and manipulation to develop an effective control system. It provides protection to the plant throughout its cultivation period and proliferates rapidly in soil and leaves no residue. Tea plants are challenged by several root, stem and foliar diseases. Fungi possess a number of characteristics that make them potentially ideal bio control agents. They can germinate to grow and control the target population there by making continual re-inoculation with the bio control agent. The preliminary investigation reflects the growth of Pstalotiopsis theaeis controlled by the isolated bacteria which could be a great potential biocontrol agent for the control of various diseases of tea in this region.
Phytochemical Analysis and Antioxidant Assay of Pseuderanthemum crenulatum (Wall.Ex Lindl.) Radlk.
Authors: P.S. Preetha , Lekshmi A. Sree
Published: January 2025

India has a large diversity of plants. Plants have been used as a source of therapeutic processes. Pseuderanthemum crenulatum (Wallich Ex Lindley) Radlk belongs to Acanthaceae family. The objective of the study was Phytochemical analysis and antioxidant assay in methanolic extracts of Pseuderanthemum crenulatum (Wall.ex Lindl.) Radlk leaves. The antioxidant effect of methanolic extraction of plant leaves was studied by DPPH (1, 1diphenyl-2picryl hydrazyl) radical scavenging assay. The antioxidant studies done by DPPH assay revealed low antioxidant activity against ascorbic acid as reference standard. Absorbance was measured immediately at 515 nm by UV spectrophotometer. Lower absorbance of reaction mixture indicated higher free radical activity. As increasing concentration, the absorbance of sample was decreased. The methanolic extract of dried leaves of Pseuderanthemum crenulatum revealed the presence of secondary metabolites such as phenols, flavonoids and saponin. It indicates that the plant has a therapeutic activity.
Design and development of double head dehuller and its performance testing using selected minor millets
Authors: P. Hemasankari  , Rao B. Dayakar , Prasanna E. Sai , Tonapi Vilas. A. , R. Kailappan  , Sathyavathi C. Tara
Published: January 2025

A double head dehuller was designed and developed and its performance evaluation was done using selected minor millets of barnyard, brown top, kodo, proso and foxtail millet. The main components of the machine included hopper of 5kg capacity, a double grain crushing chamber, an outlet grain chute, blower for husk aspirator, a cyclone outlet for husk separation and a prime mover motor of 3hp power. The machine was operated both at no load and load condition for calibration and determination of capacity and efficiency. Under load condition, it was operated for 15 minutes and the husk and dehulled grain were collected separately. In double pass dehulling the hull removal is more compared to single pass dehulling, it is in the order of barnyard millet  brown top millet  kodo millet  proso millet  foxtail millet. In double pass, the minimum dehulling percentage is 18.2% and maximum hull removal is 22.9%. Approximately in double pass, 10% more of hull removal than in single pass dehulling. Total yield ranged between 77.1 % to 81.8%. With the foxtail millet the dehulling efficiency was 64.07%, head millet recovery was 95.21%, broken grain recovery was 4.79%, dehuller performance index was 61, capacity of the double head dehuller is 96.4kg/h and husk recovery is 31.12%. With the barn - yard millet, the dehulling efficiency was 38.27%, head grain recovery was 88.98%, broken grain recovery was 11.02%, dehuller performance index was 34.05%, capacity was 74kg/h and husk recovered is 51.35%. Three replications for both single pass and double pass dehulling were made separately and the average values were taken. Then the values were tested for its statistical significance using SPSS software and it was found to be significant at 5% level of significance (p0.05). The statistical analysis was done using SPSS 16.0 software.
ESG: Business Responsibility and Sustainability Reporting in India
Authors: Gaikwad Latika Dnyaneshwar
Published: January 2025

In the present era, major globally significant concerns are inclusive growth, adaptation to changes in climate and mitigation, and the shift to a sustainable economy. Environment, Social, and Governance (ESG) concerns, like changes in climate conditions and socioeconomic disparity, have become more prominent since the pandemic. Companies play major role in an economy. As it is essential to report on financial and operational performance of a company it is also now imperative to account and report for company’s performance in the terms of various aspects associated with sustainability. This study discusses about the ESG reporting framework in India. This paper also discusses in detail ESG-Business Responsibility and Sustainability Reporting framework in India.
Effect of Soil and Foliar Applied Zinc and Iron Fertilization on different Growth attributes of Bread Wheat (Triticum aestivum L.) Cropin Typic Haplustepts
Authors: Kumar Pawan , Meena S.C. , Meena R.H.
Published: January 2025

A two years investigation conducted at Instructional Farm, RCA, MPUAT, Udaipur during Rabi 2022-23 and 2023-24 to evaluate the impact of different methods of zinc and iron through soil and foliar application on growth attributes of bread wheat (Triticum aestivum L). The soil of experimental site was slightly alkaline in soil reaction (8.24 and 8.25) and clay loam in texture. The experiment was laid out under FRBD with three replications. The experiment comprised of 5 levels of soil applied Zn and Fe, S1 (10 kg ZnSO4 ha-1) S2 (20 kg ZnSO4 ha-1), S3 (25 kg FeSO4 ha-1), S4 (50 kg FeSO4 ha-1) S5 (10 kg ZnSO4 ha-1 + 25 kg FeSO4 ha-1) and three levels of foliar applied zinc and iron namely F1 (0.5% ZnSO4 ha-1), F2 (0.5% FeSO4 ha-1) F3 (0.5% ZnSO4 ha-1 + 0.5% FeSO4 ha-1) at two different growth stages (30 DAS and 45 DAS) along with one absolute control. The result showed that soil application and foliar application of zinc and iron increased the growth parameters of crop significantly. The result showed that among control verses rest treatments, combined soil applied zinc and iron @10 kg ZnSO4 ha-1 + 25 kg FeSO4 ha-1 (S5 ) recorded highest dry matter accumulation (g) at 90 DAS and at harvest, plant height (cm and number of total tillers (0.5 m2 ) at harvest in crop over control.
Productivity and Soil Nutrients in Skip Row Planting of Deshi Cotton with Various Intercrops under Rainfed Conditions
Authors: Sumitra Gugulothu
Published: January 2025

The study entitled “Productivity and soil nutrient dynamics in skip row planting of deshi cotton with various intercrops” was conducted at Post Graduate Research Farm, Agronomy Section, College of Agriculture, Dhule (Maharashtra) during kharif season of 2018-19. The results revealed that sole skip row planting of cotton registered the highest seed cotton yield (`1966.48 kg ha-1) than skip row planting of cotton + pearl millet (2:1) (`925.70 kg ha-1), however, it is on par with rest of the treatments. Similar trend was observed in respect of yield of stalk kg ha-1. There was a drastic reduction in seed cotton yield ha-1 due to pearl millet intercropping (52.9 %) as compared to sole skip row planting of cotton. The least yield reduction in cotton was observed with black gram (3.06%) and green gram (3.62%) as intercrops.The cost of cultivation of skip row planting of cotton + pearl millet (2:1) is higher (`40491ha-1) and minimum cost of cultivation (`37596 ha-1) was recorded in sole cotton and sole skip row planting of cotton. The highest gross monetary returns (`112960 ha-1), net monetary returns (`73546 ha-1) and B:C ratio (2.87) were obtained with the skip row planting of cotton + green gram (2:1). Skip row planting of cotton + pearl millet (2:1) recorded lowest gross returns (`69079ha-1), net returns (`28588 ha-1) and B:C ratio (1.71). The available soil nitrogen content was significantly higher in skip row planting of cotton+ green gram (2:1) at 178.75 kg ha-1. The available phosphorus content was higher in skip row planting of cotton + soybean (2:1) at 29.89 kg ha-1 and the available potassium content was higher in skip row planting of cotton and black gram (2:1) at 248.80 kg ha1 ). Minimum available nitrogen (144.25 kg ha-1), phosphorus (16.08 kg ha-1) and potassium (224.93 kg ha-1) content was observed in the skip row planting of cotton + pearl millet (2:1).
Stress and Burnout Management Among Teachers in Enugu State, Nigeria: Intervention of Cognitive Behavioural Therapy
Authors: Vivian Madu Chioma , Asuquo Effanga Offiong , A. Ezurike Chukwuemeka , Chidiebere Isilebo Nwamara , Ukpai Eke N. , V. Amoke Chijioke , Lawrencia Okolie Uchenna. , Amaeze Eze Fidelis , Faith Diara Chinwe
Published: January 2025

The study investigated intervention effects of cognitive behavioural therapy on stress and burnout management among teachers in Enugu State, Nigeria. The teachers’ stress was measured with Resenberg Occupational Stress Scale (ROSS) with an internal consistency reliability coefficient of 0.83. The ROSS has nine components of stress such as Student Behaviour, Administrators’ Relation, Teacher Relation, Parent/Teacher Relation, Time Management, Intrapersonal Relation, Physical Symptom of Stress, Emotional Symptom of Stress and Stress Management Technique with 4 items in each of the components. The Maslach Burnout Inventory (MBI) was used for data collection. The MBI has 25 items and was developed by Maslach and Jackson 1981. The internal consistency reliability of MBI was established through Cronbach alpha which gave coefficients of 0.87. The participants are 162 teachers identified with Stress and Burnout symptoms. The teachers were put in two groups- experimental and control groups. The experimental group that received CBT-treatment has 82 teachers while the control group has 80 teachers respectively. A therapist’s guide to brief cognitive behavioral therapy Developed by Clerk in 2006 (42) was used as intervention by the study as the treatment. The assistants adhered to the outlines of Clerk in the intervention process that lasted for four weeks. A placebo on conventional counselling was given to the control group. The study revealed that CBT significantly increased stress and burnout management among teachers in secondary schools in Enugu State, Nigeria. The school administrators should also avoid conflicting role assignment of responsibility to the teachers, involve the teachers in decision making, provide conducive teaching environment through the support of appropriate instructional materials and allow the teachers to enjoy their free periods without interferences.