bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Shoulder and Elbow Range of Motion and Arm Muscle Strength in Humerus Fractured Patients Treated with Operative and Non-operative at Dr. Soebandi Hospital
Authors: Hariyono Dedy Chandra , Hasan Muhamad , Prasetyo Rony
Published: December 2017

Humerus fracture is a disruption of normal architecture in humerus bone . This study was conducted to identify The Range Of Motion (ROM), muscle strength of arm and analyze the comparison of the ROM and muscle strength on humerus fracture patients between operative and non-operative treatment. This research used non-experimental study with cross-sectional design. Observed variables were Range of Motion and muscle strength each measured by goniometer and muscle strength scale, respectively. Comparing to these circumstances, there were significant difference in shoulder abduction, shoulder flexion, shoulder extension, elbow extension and elbow flexion between operative treatment patients and non-operative treatment patients at dr. Soebandi Hospital Jember.

Keywords : humerus fracture, range of motion, muscle strength.
The Difference of the Knowledge, Stigma and Attitude between The First Year and Final Year Student of Medical Faculty of Jember University toward Mental Disorders
Authors: Teresha Dinda Ayu , Tyaswati Justina Evy , Widhiarta Kadek Dharma
Published: December 2017

Mental disorders is one of the health problems in developing countries and developed countries. One of the biggest problems faced by those with mental disorders is the presence of that and negative attitudes due to lack of public knowledge. Several previous studies have found that education increase knowledge and change the stigma and negative attitudes on medical students. The purpose of this study was to analyze the differences of knowledge, stigma and attitude between first year and final year student of the Medical Faculty of Jember University toward mental disorders. This research was a quantitative research with cross sectional approach. The samples were the students class of 2012 and 2014. The independent variable was the class of the students, while the dependent variable was knowledge, stigma, authoritarianism, benevolence, social restrictions, and istatistik of health community. The data was analyzed using chi-square test. Based on the test result, it was found that the variables with a significant difference is stigma (p= 0.001) and authoritarianism (p = 0.025). In conclusion there were significant differences on stigma and attitudes of authoritarianism between the first year and final year students to the mental disorders. Keywords: Stigma, Authoritarianism, Benevolence, Social Restrictiveness, Community Mental Health Istatistik
Hydroquinone Identification in Whitening Creams Sold at Minimarkets in Minomartini, Yogyakarta
Authors: Astuti Dian Wuri , Prasetya Hieronimus Rayi , Irsalina Dina
Published: December 2017

Whitening cream is a cosmetic which is contains chemicals and other materials that can etiolate black (brown) stain on the skin. Hydroquinone is a supplemental ingredient in whitening cream. Hydroquinone is the active ingredient that can control the production of uneven pigment, rather serves to reduce or inhibit the formation of melanin. The use of hydroquinone in cosmetics should not be more than 2%.The excessive use of hydroquinone can cause oochronosis,a rough, speckled bluish skin. The purpose of this study is to determine whether or not there are any hydroquinone in whitening cream sold at Minimarket in Minomartani, Yogyakarta. If found, further testing is done to determine the level of hydroquinone in it. This research describes the presence or absence of hydroquinone in the whitening creams and find out how much the percentage is. The method used is Thin Layer Chromatography (TLC) and serimetri titration. The qualitative study test results that 64% of the samples positively contain hydroquinone, whereas from the quantitative assay it is obtained that 89% of the samples are not suitably qualified according to Permenkes No.445/MENKES/PER/V/1998. There are 9 out of 14 whitening cream brands that contain hydroquinone and 8 of them contain levels of hydroquinone more than normal (> 2 %).Keywords: face whitening cream, hydroquinone, Thin Layer Chromatography, serimetri titration.
The Effect of Mirabilis jalapa Leaf Ethanolic Extract against Streptococcus pyogenes
Authors: Pambudi Bagus Satrio , Suswati Enny , Firdaus Jauhar
Published: December 2017

Streptococcus pyogenes is a Gram positive bacteria that commonly cause disease in human. If not treated immediately, this bacteria can cause serious complication such as reumatic fever that causing heart valve tissue damage. Penicilin, drug of choice to eradicate S. pyogenes, oftenly cause various side effects such as anaphylaxis. This study aimed to investigate the effect of Mirabilis jalapa leaf ethanolic extract against S. pyogenes growth using in vitro techniques. The study design was a quasi experimental design. S. pyogenes culture as the study subject were divided into positive control group (penicilin V 100 IU), negative control group (NaCMC 0,5%), and eight treatment groups that were given with M. jalapa leaf ethanolic extract as much as 0,1 mg/ml, 1 mg/ml, 5 mg/ml, 10 mg/ml, 20 mg/ml, 30 mg/ml, 40mg/ml, and 50 mg/ml. After 24 hours incubation periods, the inhibition zone were found in all treatment group except in concentration 0,1 mg/ml. This study showed that M. jalapa leaf ethanolic extract could inhibit the growth of S. pyogenes. There was significant correlation between the concentration of M. jalapa leaf ethanolic extract and the diameter of inhibition zone (p=0,00), the higher concentration of M. jalapa leaf extract, the larger diameter of inhibition zone of S. pyogenes. Keywords: Mirabilis jalapa, leaf extract, antimicrobial activity
Diagnosis Code Accuracy Analysis Of Acute Gastroenteritis Disease Based on Medical Record Document in Balung Hospital Jember
Authors: Karimah Rinda Nurul , Setiawan Dony , Nurmalia Puput Septining
Published: December 2017

Accuracy analysis of replenishment diagnosis codes on the document medical records is very important because if the diagnosis code is not right or not in accordance with the ICD-10, it can cause a decline in the quality of care in hospitals as well as the influence of data, information reporting, and accuracy rates of INA-CBG's that are currently used as a method of payment for patient care. The purpose of this study was to analyze the accuracy of diagnosis codes acute gastroenteritis disease in hospitalized patients by medical record documents in the first quarter of 2015 in the Balung Hospital Jember. This research used qualitative data. Acquisition of data from this study through interviews and observations. Results obtained from the observation of medical record documents at the inpatient unit in the first quarter 2015 in Balung Hospital Jember, there are some numbers determining the accuracy of disease diagnosis codes as many as 17 medical record documents with acute gastroenteritis illness and the determination of improper diagnosis codes as many as 63 medical records document acute gastroenteritis illness. After analyzing, the cause of the problem is the accuracy of the diagnosis that affects the accuracy of writing code, beside it has never been disseminated to physicians and medical records personnel related to the management of medical records. Therefore, it is necessary to carry out activities that can improve the accuracy of disease diagnosis code and quality of human resources, among others, include doctors and medical records personnel in training and socialization related to the management of medical records. Key Words : Diagnosis codes , medical record, acute gastroenteritis
The Spermicide Effect from Methanol Extract of Kalangkala Seed (Litsea angulata) to Spermatozoa Mice (Mus musculus)
Authors: Akmal Rommy , Kuswanto Kuswanto , Fahrunnisa Syarifah , Rahmi Ridha Aulia , Bayanil Nur Ema Putri , Nurliani Anni
Published: December 2017

Men involvement in family planning needs to be increased by providing natural spermicide from natural source which is safer. One of them is kalangkala seed which is endemic plant in South Kalimantan. The spermicide effect from methanol extract of kalangkala seed to mice spermatozoa was studied in this research by in vitro method. Spermatozoa suspension was taken from epididymis cauda of twenty five male Balb/c mice. This research used a complete randomized design with five treatments i.e control which without any addition; spermatozoa suspension + NaCMC 0.5%; spermatozoa suspension + methanol extract of kalangkala seed 0.1%; spermatozoa suspension + methanol extract of kalangkala seed 0.3%; and spermatozoa suspension + methanol extract of kalangkala seed 0.5% with five repetitions for each treatment. The result of this study showed that methanol extract of kalangkala seed caused decrease of motility and movement velocity mice spermatozoa until achieve zero value in 0.5% concentration. Key words: kalangkala seed, mice, spermatozoa, natural spermicide
Overview of Depression in The Elderly of UPT Pelayanan Sosial
Authors: Mulyadi Relang Rizky , Mardijana Alif , Nurdian Yudha
Published: December 2017

Depression is a prolonged sadness and a feeling or abnormal. Can be used to demonstrate a variety of phenomena, such as signs, symptoms, syndrome, emotional, reaction. Depression is more common in older people than depression in the general population with a prevalence rate of 25-50%. Elderly according to article 1, paragraph (2), (3), (4) of Law No. 13 of 1998 on the health of the elderly is said that a person who has reached the age of 60 years. The purpose of this study to determine the incidence and the general picture of depression that occurs at the level of the elderly who live in UPT Pelayanan Sosial Lanjut Usia Kabupaten Jember. This study is observational analytic cross sectional design. The variables observed in this study is the age and level of depression. Respondent has been investigated by using the GDS (Geriatric Depression Scale). Population in this study was all elderly that live in UPT Pelayanan Sosial Lanjut Usia Jember as much as 43 respondents. Spearman Rho analysis showed significance level 2.57 which shows 2.57> 0.05 p. This means that there is no significant relationship between age of elderly with depression levels among respondents in UPT Pelayanan Sosial Lanjut Usia Kabupaten Jember. Key words: Depression, Elderly.
The Activity of Ethanolic Extract of Cyclea barbata Miers as Inhibitor of Bacterial Biofilm Formation of Salmonella typhi
Authors: Permanasari Dimes Atika , Sakinah Elly Nurus , Santosa Ali
Published: December 2017

Biofilm is a matrix consist of extracelullar polysaccharides from the replication of microbial cells that are irreversibly attached on the cell surface. Biofilm in bacteria S.typhi strain DT104 contains food substance for protection. Biofilm can be attached to the clutery, causing food contaminaton. Cyclea barbata Miers is a plant has flavonoid that can inhibited bacteria biofilm formation. Flavonoid is phenolic compounds that has function as antibacterial by forming complex compounds disturbing the integrity of cell membranes and inhibiting biofilm. This study aims to determine the activity of the Cyclea barbata Miers as inhibitor of S.typhi DT 104 biofilm formation. This study used Quasy Experimental design with completely randomized design This study used 28 samples consist of 5 doses groups (0.29 mg/ ml, 0.33 mg / ml, 0.40 mg / ml, 0.50 mg / ml, 0.67 mg / ml), positive group (a bacterial suspension with H2O2) and negative group (a bacterial suspension with H2O) The result showed that the increasing doseof extract will decrease the biofilm formation revealed by decreasing of Optical Density and showed One Way Anova test resulted p = 0.004. In conclusion, the ethanolic extract of Cyclea barbata Miers was able to inhibit S.typhi DT 104 biofilm formation and there was a correlation between the concentration of ethanoic extract of Cyclea barbata Miers and inhibition of S.typhi biofilm formation. Key words: biofilm, Cyclea barbata Miers, S.typhi
The Effectivenes of Red Rice to Decrease Total Cholesterol in Type 2 DM Patients
Authors: Pradini Wydi Ulfa , Marchianti Ancah Caesarina Novi , Riyanti Rini
Published: December 2017

Diabetes mellitus (DM) is a group of metabolic diseases with hyperglycemia characteristic that happens because anomaly of insulin secretion or insulin activity. Insulin deficiency in type 2 DM caused dislipidemia. Red rice are contain fiber, essential fatty acid and Gamma Amino Butiric Acid (GABA). This research intended to know the effectiveness of red rice to decrease total cholesterol levels of patient with type 2 DM. Clinical test with quasi experimental and research design non randomized control-group pretest-postest design was used for the research method. Total samples of this research are 36 samples. The treated group was given the red rice during 6 days on breakfast and dinner, while the control group did not have any intervention. The research showed that average cholesterol levels in the beginning and finale of treated group was 235,69 mg/dL and 198,56 mg/dL, while average cholesterol levels in the beginning and finale of control group was 235,72 mg/dL and 256,50 mg/dL. From this research, red rice has effective to decrease total cholesterol levels of patients with type 2 DM.Keywords: Diabetes mellitus, Red Rice, Cholesterol total levels
The Effect of Hyaluronic Acid on MMP-9 Expression in Trabecular Meshwork Cell Culture of Patient with Primary Open Angle Glaucoma
Authors: Komariah Cicih , Effendi Ma’sum , Sujuti Hidayat
Published: December 2017

In primary open angle glaucoma, decrease of hyaluronic acid level is related to extracellular matrix deposition of trabecular meshwork. Extracellular matrix deposition will increase humor aqueous outflow resistance which in turn increase the intraocular pressure. MMP-9 as one of matrix metalloproteinase (MMP) family, has a high potency to degrade the extracellular matrix. The expression of MMP-9 can be activated by hyaluronic acid through its binding with CD44 as hyaluronic main receptor. The aim of this research is to determine the effect of hyaluronic acid on MMP-9 expression in trabecular meshwork cell culture of patient with primary open angle glaucoma by immunocytochemical method. Trabecular meshwork cell culture were exposed to hyaluronic acid at four different concentration (0mg/ml, 1 mg/mL, 3 mg/mL, 6 mg/mL). After 24 hours incubated, we find a significant difference of MMP-9 expression between control group and group with hyaluronic acid. There was significant correlation between hyaluronic acid and MMP-9 expression. Hyaluronic acid exposure will increase MMP-9 expression in trabecular meshwork cell culture. This finding suggest that hyaluronic acid can influence the resistance of humor aqueous outflow in trabecular meshwork by up-regulating MMP-9 expression, and therefore will increase extracellular matrix degradation.Key words : hyaluronic acid, primary open angle glaucoma, MMP-9
Antihiperlipidemi and Atheroprotective activity of Kepuh (Sterculia foetida) Leaves Ethanolic Extract on High-Fat-Diet Rat Models
Authors: Sutejo Ika Rahmawati , Rasyada Imama , Yuniar Annafira
Published: December 2017

Cardiovascular disease causes the highest mortality rate in the world. Atherosclerotic plaque is the most common etiology of cardiovascular disease. High levels of cholesterol in circulation is the pathophysiology of atherosclerosis formation. Atherosclerosis risk can be lowered to 20-40% with statins. Statins are effective in lowering total and LDL cholesterol, but these drugs have been reported to cause side effects. Therefore, it needed an alternative medicine to prevent the process of atherosclerosis using kepuh leaves (Sterculia foetida). Flavonoids contained in Kepuh leaves improve lipid profiles. The aims of this study is to prove the effectiveness of Sterculia foetida in lowering cholesterol, triglyceride and reduce the amount of foam cells on high-fat-diet induced rats. The research design is quasi-experimental with post test only design. Animals are grouped into normal group, negative control group and three treatment groups that were given kepuh leaves extract at the dose of 200 mg/kgBB, 400 mg/kgBB, and 800 mg/ kgBB. Rats were given high-fat diet of initial intravenous adrenaline injection 0.006 mg/200 gBB and duck egg yolks 5 g/kgBB for 21 days. Cholesterol and triglycerides were measured by enzymatic methods and aortic tissue stained with HE. ESf reduce cholesterol significantly and reduce the amount of foam cells on aorta.Keywords: cholesterol, triglyceride, kepuh leaves, foam cell, high-fat-diet
Slow Release Metformin Effect in Weight Loss and Total Calorie Intake in Obese Volunteers
Authors: Abrori Cholis , Tiya Lucky , Rosalina Deti
Published: December 2017

Obesity can cause serious problems that will lead to poor quality of life, increased morbidity and mortality rate. Slow-release metformin will work longer in the body with a single dose everyday be an alternative drug for weight loss. The purpose of this study was to compare the effectiveness of slow-release metformin compared to metformin regular to body weight and calorie intake in volunteers with obesity. The study was conducted on 16 volunteers who were divided into two groups in pairs. Volunteers will be measured weight and calorie intake with a 24-hour food recall method, data was taken at the time before the intervention, the end of week 1st, 2nd, 3rd, and 4th. The result obtained weight loss better in the group receiving slow-release metformin by 5.08% compared to the group receiving regular metformin by 2,60%, but there was no significant difference between the groups in terms of calorie intake during the study. The conclusion of this study is a slow-release metformin is greater in weight loss than regular metformin, but does not affect the amount of calorie intake.Keywords: Metformin, slow-release, weight loss, calorie intake, obesity
The Difference in Lemuru Fish Oil Duration of Administration on Connective Tissue Fibroblast Cell Count in Rheumatoid Arthritis Rat Model
Authors: Fillah Asyirah Mujahidah , Normasari Rena , Rachmawati Dwita Aryadina
Published: December 2017

Rheumatoid arthritis is a joint chronic inflammation process leadingto progressive distruction.Cytokinessecreted from chronic inflammation increases fibroblast cell number that synthesize matrix metalloproteinase. Non steroidal anti inflammation drugs administrated to lighten inflammation symptoms had several side effects that increase the urge to discover an alternative antiinflammation with lower side effect like lemuru fish oil. This true experimental study with randomized post test only control group design aimed to investigate the difference in lemuru fish oil duration of administration on connective tissue fibroblast cell count in rheumatoid arthritis rat model. The One Way Anovatestrevealed that there are at least two group means that are statistically significant different from each other with a p value of 0,004. Post Hoc LSD analysis result indicate a significant difference after21 days duration of administrationcompared to 7 days administration with significance value of 0,038.It can be concluded that there is a significant difference in lemuru fish oil administration after21 days duration.
Effects of Herbal Forte Rice as Replacement of Carbohydrate to Insulin Resistance in Patients with Type 2 Diabetes in Sumbersari Health Center Jember
Authors: Rahmah Dina Faizatur , Marchianti Ancah Caesarina Novi , Riyanti Rini
Published: December 2017

The population of type 2 diabetes mellitus sufferer continuously increases due to the increase of insulin resistance characterised by the rise of the secretion insulin. Insulin resistance is affected by several factors such as the lack of physical activity, obesity, and unhealthy diet. One of the characteristics of the unhealthy diet is the high consumption of carbohydrates.Whereas Indonesian prefers to have carbohydrate sources from food which has high glycemic index such as rice so thatit makes the glucose in the blood increased rapidly. This condition causes more and faster insulin secretion and can affect insulin resistance. The purpose of this study is to know the effectiveness of herbal forte rice as a substitute of the main carbohydrate in the state of hyperinsulinemia suffered by 15 patients of type 2 diabetes mellitus in Puskesmas (community health center) Sumbersari Jember. This study is a clinical trial with a quasi experimental method and crossover design. In this study, the sample is interviewed by characteristics (age, gender) and the early consumption patterns using 24-hour food recall three times at different times. Samples acted as a control group once the experimental group. The control group did not receive any treatment, while the experimental group received the herbal forte rice as much as 100 grams for 7 consecutive days in the morning (at 06.30 am). After washing out period for 9 days, experimental group switched into control group. At the end of the period (7 days), data of fasting blood glucose and fasting insulin were collected then counted by HOMA-IR formula. The result of the study based on the paired t test p=0.001 in comparison to the state of the control and experimental group. The conclusion of this study is there is a changing state of insulin resistance with the replacement of food based on glycemic index.
The Effect of Purple Sweet Potato Extract on The Circulating Endothelial Cell (CEC) levels in Rat Model of Diabetes
Authors: Sari Emilia Puspita , Junaidi Edi , Fatmawati Heni
Published: December 2017

Diabetes mellitus is a metabolic disease with impaired metabolism of carbohydrates, fats and proteins are characterized by hiperglycemia caused by insufficiency of insulin secretion and insulin resistance. Diabetes mellitus is the leading cause of death in Indonesia, especially in developing countries. Most (90%) classified as type 2 diabetes mellitus and 10% of type 1 diabetes mellitus. In DM, increased oxidative stres. DM oxidative stres due to the increase of free radicals in the body. Oxidative stres can lead to irreversible endothelial injury that would lead to the loss of endothelial cells characterized by the expression of CD 146. Ipomoea batatas L. anthocyanin-containing compound is an antioxidant that can reduce free radicals and reduce oxidative cell damage caused by free radicals. From the analysis of the data obtained Ipomoea batatas L. mempuyai influence on the content of the CEC of 42.5%.
Humoral Response to Anopheles maculatus and Anopheles sundaicus Salivary Gland Proteins
Authors: Armiyanti Yunita , Widodo Widodo , Fitri Loeki Enggar , Sardjono Teguh Wahju
Published: December 2017

The salivary gland of female Anopheles mosquito has important role in malaria transmission by salivary proteins that enhancing Plasmodium transmission. The mosquito saliva contains vasomodulatory and immunomodulatory components that inhibit the physiological response of the host. Therefore, the pathogen infects the host without any resistance. The salivary proteins also induce the production of antibody IgG in the host after exposed by the Anopheles mosquito bites repeatedly. This study aims to measured the antibody response of inhabitants living in malaria endemic areas (Kalirejo viilages, Kokap, Kulonprogo) to salivary gland proteins of An. maculatus and An.sundaicus. The level of antibody response was measured by ELISA and analyzed with T test or Anova test for normal distribution of data and Mann Whitney test or Kruskal Wallis test for the data were not normally distributed. The result showed that the level of anti-salivary gland homogenate IgG from sera of people living in malaria endemic area was significantly higher than people living in non-malaria endemic area and negative control (p<0.05). Sera from inhabitants living in Kalirejo village showed that the level of antibody response to both salivary gland homogenate of An.sundaicus and An.maculatus were not significantly different (p<0.05). It was concluded that exposure to An.maculatus and An.sundaicus bites repeatedly could trigger the production of anti-salivary gland proteins IgG antibodies that recognized antigenic proteins from the salivary glands.
Administration of Oral Therapy For Gonorrheal Urethritis Patients With Local Complications In Men: Case Reports
Authors: Harningtyas Citra Dwi
Published: December 2017

Urethritis gonorrhea is the most prevalent venereal disease today and can be found all over the world. Timeliness of treatment, correct selection of drugs with adequate doses can eliminate infections that affect the individual, prevent the development of complications, prevent further transmission and avoid germ resistance. This article reports, 24-year-old male patient with a diagnosis of gonore urethritis who came to polyclinic Skin and Veneral at Hospital Syaiful Anwar Malang. Patients come with complaints of pus out of the genitals without itching. Patients also complain of pain during urination, as well as urinating in small volume and often. On examination of external urethra urifisium area obtained ectropion, purulent discharge, and hyperemia macula. There is a lump and duh at the tip of the genitalia caused by inflammation of the paraurethral glands. From the investigation found diplococcus bacteria Gram negative intrasellular PMN. The causative therapy given is a single oral dose of Oral 400mg. Evaluation was done 3 days after treatment and improvement was obtained.

Keywords: gonorrhea urethritis; oral urethritis therapy; uretritis gonorrhea complications
Comparative Effectiveness of Corn Oil (Zea mays) with Pure Coconut Oil (Cocos nucifera L.) to Reduced Glucose Blood Levels of Alloxane Injected Wistar Rats
Authors: Firdausi Khadijah Nur Al , Sugiyanta Sugiyanta , Wulandari Pipiet
Published: December 2017

Epidemiological studies show an increased incidence of diabetes mellitus. The initial therapy of diabetes mellitus is a diet treatment. The recommended intake of fat is a Saturated Fatty Acids (SFA) <7% and a Polyunsatturated Fatty Acid (PUFA) <10% of calories. The corn oil contains PUFA and the virgin coconut oil contains SFA as the main component. Aims of this study was to compare the effectivity of corn oil (Zea mays) and virgin coconut oil (Cocos nucifera L.) in decreasing blood glucose level in alloxane-ijnected wistar rats. This was a laboratory experiment research, used the posttest-only control design. The negative control group was wistar rats injected by aquabidest and standard feed diet (K-); the positive control group was alloxane-injected rats with standard feed diet (K+); alloxane-injected rats with standard food diet and 0.54 mL of corn oil/day for 28 days were P1 group; alloxane-injected rats with standard diet food and 0.54 mL of virgin coconut oil/day for 28 days were P2 group. Statistical analysis using the one way ANOVA test showed that the corn oil and virgin coconut oil decrease blood glucose level, but there was no significantly difference in decresing of blood glucose level between P1 and P2. This study concluded that the corn oil and the virgin coconut oil have the same effectiveness in decreasing blood glucose level in wistar rats injected with alloxane.Keywords: Corn oil, virgin coconut oil, blood glucose level, alloxane
Green synthesis of 2-aryl-4-phenyl-quınazolıne derıvatives promoted by lactıc acıd
Authors: Adrom Belgheis , Hazeri Nourallah , Maghsoodlou Malek Taher , Lashkari Mojtaba , Fatahpour Maryam
Published: December 2017

An environmentally benign three-component synthetic method is described for the construction of 2-aryl-4-phenylquinazoline derivatives from the reaction between aldehydes, ammonium acetate, and 2-aminobenzophenone in the presence of lactic acid in a solvent-less media. The benefits of the reaction were good yields, a simple procedure, simple starting materials short reaction time, easy work-up, and cleaner reaction profiles.
A computational study on a series of phenanthrene and phenanthroline based potential organic photovoltaics
Authors: Gümüş Selçuk , Gümüş Ayşegül
Published: December 2017

A series of phenanthrene and phenanthroline derivatives were considered computationally by the application of Density Functional Theory at the B3LYP/6-31++G(d,p) level to investigate their potential usage as organic solar cell components, thermally activated delayed fluorescence and nonlinear optic compounds. The structures were constructed as a D-π-A motif in order to increase the ability to achieve intramolecular charge transfer enabling them to act as organic semiconductors. The inter-frontier energy gap of all compounds was found to be in the range of semiconductors. The thermally activated delayed fluorescence (TADF) properties of the compounds were also discussed in relation to the results obtained by TD-DFT calculations. Some of them possessed very narrow triplet-singlet transition energy leading to future TADF applications. Moreover, the nonlinear optic characteristics of all compounds were investigated through calculations of the total molecular dipole moment (μtot), linear polarizability (αtot) and hyperpolarizability (βtot). The results indicate the potential nonlinear optic property of all of the systems.
Investigating the presence of misconceptions of 8th grade students through multiple-choice questions at national chemistry competition test
Authors: Stojanovska Marina , Petruševski Vladimir M.
Published: December 2017

A study was conducted to test the level of conceptual understanding of certain chemistry concepts defined in the national curriculum in Macedonia among 8th grade students who participated in the National chemistry competition in the 2016/17 school year. The students were tested on the following topics: state of matter, metals and non-metals, elementary substances, compounds and mixtures, chemical reactions and introduction to organic chemistry. An analysis of the multiple-choice questions was performed in order to categorize students’ achievements in four areas of conceptual understanding (satisfactory conceptual understanding, roughly adequate performance, inadequate performance, and quite inadequate performance) according to the percentage of students who correctly answered the test items. Furthermore, the findings revealed three misconceptions and several vague and erroneous notions present in students’ minds.
Asupan Energi dan Protein Berhubungan dengan Gizi Kurang pada Anak Usia 6-24 Bulan
Authors: Jati Dewi Kencono , Nindya Triska Susila
Published: December 2017

Background: Children under two years of age are susceptible to nutritional problems. Nutrient intake are needed for optimal growth and mental development. Inadequate energy intake in the long run can lead to protein energy malnutrition.Objectives: The purpose of this study was to analyze the association energy and protein intake with nutritional status of children aged 6 to 24 months. Methods: This research used cross sectional design aprroach.  The subjects of this study were 62 children under two years (aged 6-24 months). Selection of sample was using simple random sampling Data was collected through interviews using a structured questionnaire, nutrient intake using 2x24hours recall, and weight measurement. Data was analyzed using Chi-square test. Results: The results showed that majority of the children had inadequate energy intake, adequate protein intake, 24.2% were underweight. There was a correlation between energy intake (p=0.044) and protein intake (p=0.038) with nutritional status WAZ. Conclusion: The conclusion of this study is  energy and protein intake contribute to underweight incidences among children aged 6-24 months. Therefore, it could be advised to increase high energy and protein intake for optimum growth.ABSTRAK Latar belakang: Anak dengan usia di bawah dua tahun rentan mengalami masalah gizi. Asupan gizi dibutuhkan untuk pertumbuhan dan perkembangan fisik dan mental. Asupan energi yang tidak mencukupi dalam waktu jangka panjang dapat menyebabkan gizi kurang yang berdampak pada kekurangan energi-protein. Tujuan: Tujuan dari penelitian ini adalah untuk menganalisis hubungan asupan energi dan protein dengan status gizi berdasarkan BB/U pada anak usia 6-24 bulan di wilayah kerja Puskesmas Klampis Ngasem, Surabaya.Metode: Penelitian ini menggunakan desain cross sectional. Subyek dari penelitian ini adalah 62 bayi di bawah dua tahun (baduta) berusia 6-24 bulan yang didapatkan dari metode simple random sampling. Pengumpulan data dilakukan dengan menggunakan kuesioner terstruktur, asupan gizi dengan recall 2x24hrs, dan pengukuran berat badan. Teknik analisis data dilakukan dengan uji statistik Chi-square. Hasil: Hasil penelitian menunjukkan bahwa sebagian besar baduta memiliki asupan energi tidak adekuat, asupan protein adekuat, dan 24,2% mengalami underweight. Terdapat hubungan asupan energi (p=0,044) dan asupan protein (p=0,038) dengan status gizi BB/U.Kesimpulan: Energi dan protein berkontribusi terhadap kejadian underweight pada baduta. Oleh karena itu, disarankan selalu melakukan peningkatan konsumsi pangan dengan memberikan asupan makanan yang mengandung energi dan protein untuk pertumbuhan yang optimal.
Pengaruh Penambahan Tepung Kacang Tanah (Arachis hypogaea L.) terhadap Daya Terima, Kadar Air, dan Kadar Protein Nugget Edamame (Glycin max (L) Merril)
Authors: Santi Nevi Ruliyana , Ningtyas Farida Wahyu , Sulistiyani Sulistiyani
Published: December 2017

Background: Edamame is one of local food in Jember Regency which overflow followed, cheap, but its cultivation and utilization is deficient, especially in the form as a side dishes. Objectives: This research aimed to analyze the effect of peanut flour addition to the acceptance, water level, and protein level of edamame nugget.Methods: This research is Quacy Experimental with posttest only control group design with 4 treatments: X0, X1, X2, and X3 (edamame nugget without addition, with 10% addition, 20%, and 30%) and 16 units experiment. The acceptance will be analyzed with form Hedonic Scale Test, water level with destilation test, and protein level with Semi Mikro Kjeldahl test in Food Analysis Laboratory of Polytechnic Jember.Results: The results from this research showed the addition of peanut flour can increase accpetance (flavor, color, and texture), water level, and protein level of edamame nugget. X3 is most preferred from taste aspect, X0 is most preferred from color and aroma aspect, and X1 most preferred from texture aspect. The treatment with high water level and protein level is X3.Conclusion: there are significant addition of peanut flour againts the acceptance, water level, and protein level of edamame nugget.ABSTRAK Latar Belakang: Kedelai edamame merupakan jenis kedelai di Kabupaten Jember yang jumlahnya melimpah, harganya murah, tetapi pengolahan dan pemanfaatannya masih kurang terutama dalam bentuk lauk.Tujuan: Penelitian ini bertujuan untuk menganalisis pengaruh penambahan tepung kacang tanah terhadap daya terima, kadar air, dan kadar protein nugget edamame.Metode: Jenis penelitian termasuk quasi eksperimental menggunakan posttest only control group design dengan 4 taraf perlakuan: X0, X1, X2, dan X3 (nugget edamame tanpa penambahan tepung kacang tanah (kontrol), dengan penambahan 10%, 20%, dan 30%) dan 16 unit percobaan. Semua taraf perlakuan akan dianalisis daya terima dengan form Hedonic Scale Test di Sekolah Menengah Pertama Islam Terpadu (SMPIT) Al Ghozali Jember, kadar air dengan metode destilasi dan kadar protein dengan uji Semi Mikro Kjeldahl di Laboratorium Analisis Pangan Politeknik Negeri Jember.Hasil: Hasil penelitian menunjukkan penambahan tepung kacang tanah dapat meningkatkan daya terima (rasa, warna, dan tekstur), kadar air, dan kadar protein nugget edamame. Perlakuan yang paling disukai panelis dari aspek rasa adalah nugget edamame dengan penambahan tepung kacang tanah sebanyak 30 gram, dari aspek warna dan aroma adalah nugget edamame tanpa penambahan tepung kacang tanah, dan dari aspek tekstur adalah nugget edamame dengan penambahan 10 gram kacang tanah. Perlakuan dengan kadar air dan kadar protein tertinggi adalah nugget edamame dengan penambahan tepung kacang tanah sebanyak 30 gram.Kesimpulan: Terdapat pengaruh penambahan tepung kacang tanah terhadap daya terima (rasa, warna, dan tekstur), kadar air, dan kadar protein nugget edamame.
Hubungan Pengeluaran Rumah Tangga, Asupan Protein, Dan Asupan Zat Besi Dengan Kadar Hemoglobin Pada Pekerja Tambang Pasir Tradisional
Authors: Widyaji Syahid Kinayung , Mahmudiono Trias
Published: December 2017

Background: Anemia is one of the nutritional problem in society with low socioeconomic status. Low socioeconomic associated with lower nutritional intake do to limited access to a variety of foods.Objective: the aim of this study was to analyze the relationship netween household expenditure and intake protein with hemoglobin level among sand miner.Method: this was a cross sectional study with 51 sample sand miner was selected by simple random sampling. The data were collected through interview using questionnaire, 2x24 hours food recall, and hemoglobin level measured by Easy Touch GCHb. Data were analyzed using Pearson correlation.Result: The result showed that there were associations between household expenditure (p = 0.016) and intake protein (p = 0.037) to hemoglobin level. Conversely, there was no association between intakes of iron to hemoglobin level.Conclusion: Household expenditure and intake protein related to the hemoglobin level among sand miner.Conclusion : Patient satisfaction of food by outsourcing system was no difference from the patient satisfaction of food by self operated system.ABSTRAK Latar Belakang: Anemia merupakan salah satu masalah gizi pada masyarakat dengan status sosial ekonomi yang rendah. Pada sosial ekonomi yang rendah cenderung asupan zat gizinya rendah karena terbatasnya akses ke pangan yang beragam.Tujuan: Untuk menganalisis hubungan antara pengeluaran rumah tangga, asupan protein, dan asupan zat besi dengan kadar hemoglobin pada pekerja tambang pasir tradisional.Metode: Penelitian ini menggunakan desain cross sectional dengan besar sampel 58 pekerja tambang pasir tradisional yang dipilih menggunakan simple random sampling. Pengumpulan data dilakukan dengan wawancara menggunakan kuesioner, 2x24 hours food recall, dan kadar hemoglobin diukur dengan alat Easy Touch GCHb. Uji statistik yang digunakan adalah korelasi pearson.Hasil: Hasil penelitian menunjukkan terdapat hubungan pengeluaran rumah tangga (p = 0,016) dan asupan protein (p = 0,037) dengan kadar hemoglobin. Sebaliknya tidak terdapat hubungan  asupan zat besi (p = 0,258) dengan kadar hemoglobin.Kesimpulan: Pengeluaran rumah tangga dan asupan protein berhubungan dengan kadar hemoglobin pada pekerja tambang pasir tradisional.
Hubungan Tingkat Kecukupan Zat Besi Dan Seng Dengan Kejadian Stunting Pada Balita 6-23 Bulan
Authors: Dewi Enggar Kartika , Nindya Triska Susila
Published: December 2017

Background: Stunting is a cronic malnutrition that affects linear growth. The main cause of malnutrition is the adequacy of micronutrients in the process of linear growth. Micronutrients that relate to stunting are iron and zinc, because both of that micronutrient have necessary role in linear growth of toddlers age 6 -23 months. Objectives: The purpose of this study was to analyze correlation between iron and zinc adequacy level with stunting incidence in toddlers age 6 -23 months. Methods:  This study was an analytical study with cross sectional design. The sample size were 55 children spread over 25 Posyandu in Suci Village. The data collected using of food recall 3x24 hours, height measurement with microtoice for stunting status, and the questionnaire characteristics of children and mothers. The data were analyzed by using Fisher's Exact test. Result: The results showed 14.5% of toddlers age 6 – 23 months were stunted. 33.3% of children were given inadequate iron intake and 35.7% of children were given inadequate zinc intake. The analysis test showed there was a significant correlation between levels of iron and zinc adequacy with the incidence of stunting with p=0.02 and p=0.018. Conclusion: The proportion of stunting will increase if the toddler were given inadequate of iron and zinc. Education about the adequacy levels of iron and zinc for toddler age 6-23 months were adjusted to reduce and avoid stunting.ABSTRAK Latar Belakang: Stunting merupakan masalah gizi akibat kekurangan gizi jangka panjang yang berdampak pada pertumbuhan linier. Salah satu zat gizi mikro yang erat kaitannya dengan stunting adalah zat besi dan seng, sebab kedua zat mikro tersebut memiliki peran penting dalam pertumbuhan linier balita 6-23 bulan.Tujuan: Tujuan dari penelitian ini adalah untuk menganalisis hubungan tingkat asupan zat besi dan seng dengan kejadian stunting pada balita 6-23 Bulan.Metode: Penelitian ini merupakan jenis penelitian observasional analitik dengan desain penelitian cross sectional. Sampel terdiri dari 55 anak yang tersebar di 25 Posyandu di Desa Suci. Pengumpulan data menggunakan food recall 3x24 jam, pengukuran tinggi badan dengan mikrotoa untuk mengetahui status stunting, dan kuesioner karakteristik anak dan ibu. Data dianalisis menggunakan uji Fisher’s Exact.Hasil: Hasil penelitian menunjukkan 14,5% balita usia 6-23 bulan mengalami stunting, 33,3% anak memilliki tingkat kecukupan zat besi yang kurang dan 35,7% anak memiliki tingkat kecukupan seng yang kurang. Uji statistik menunjukkan terdapat hubungan yang signifikan antara tingkat kecukupan zat besi dan seng dengan kejadian stunting dengan p=0,02 dan p=0,018.Kesimpulan: Proporsi stunting akan meningkat jika tingkat kecukupan zat besi dan seng inadekuat. Sebaiknya dilakukan peningkatan edukasi tentang tingkat kecukupan zat besi dan seng untuk balita usia 6-23 bulan yang bertujuan untuk mengurangi dan mencegah stunting.
C-REACTIVE PROTEIN (CRP) AS A SUPPORTING MARKER OF ANTIBIOTIC EFFECTIVENESS ON CENTRAL NERVOUS SYSTEM (CNS) INFECTIONS
Authors: Olevianingrum Melawati , Yulistiani Yulistiani , Saharso Darto , Zairina Nun
Published: December 2017

Infection of the central nervous system in pediatric patients have a high mortality as well as acute and chronic neurological sequelae. Signs of the disease are unclear, so cerebrospinal fluid (CSF) test is used as a gold standard for diagnosis, but the investigation has faced many obtacles. Empiric antibiotic therapy is the key factor in reducing morbidity and mortality. Microbiological culture result is obtained within 5-7 days. The effectiveness of empirical antibiotic use is questionable. Therefore, other investigations are conducted to determine the effectiveness of antibiotics by using one marker, the CRP. This study was to analyze CRP level in supporting antibiotic therapy effectiveness in pediatric patients with central nervous system (CNS) infections. A prospective cohort study was conducted to determine the relationship of CRP with other parameters, including clinical, microbiological and laboratory, in pediatric patients with central nervous system infections. Patients meeting blood samples criteria were taken before (H0), the third day (H3) and the fifth day (H5) after antibiotics administration. This study involved 10 patients with central nervous system infections (meningoencephalitis, encephalitis and encephalitis with cerebral edema). Six patients were male, with ages less than a year. Antibiotic treatment effectiveness was associated with improved condition of the patients' CRP level. It was 3.558 ±3.196 before (H0), 3.878±2.813 on the third day (H3) and 3.891±2.204 on the fifth day (H5) after antibiotic administration. Leukocyte levels were 13.680±1.660 before (H0), 17.832±7.213 on the third day (H5), and 10.546±3.671 on the fifth day (H5) after antibiotic administration. Pearson's correlation test analysis performed on CRP and WBC parameters showed H0 p=0.981, CRP and WBC H3 p=0.621, while CRP and WBC H5 obtained significance p=0.644. There was no significant correlation observed between CRP and WBC parameters before and after antibiotic administration. In conclusion, there was no correlation of CRP levels with clinical, laboratory and micobiological parameters in patients with central nervous system infections.
DLBS1033 REDUCES BLOOD PRESSURE OF HYPERTENSIVE WISTAR-STRAIN RATS
Authors: Suryono Suryono
Published: December 2017

The purpose of this study was to determine the effects of DLBS1033 on blood pressure reduction in hypertension--induced wistar strain rats. Design used in this study was true experimental design. The study was conducted at Biomedical Laboratory, Physiology, Faculty of Dentistry, Jember University, and Clinical and Community Pharmacy Laboratory, Pharmacy Faculty, Jember University. Subjects were taken from male Wistar rats aged 2-3 months, weighing 150-200 grams, as many as 22 rats. Intervention samples were induced into hypertension by giving prednisone in a dose of 1.5 mg/kg/day orally and 2% NaCl followed DLBS1033 of 0.5 grams/kgbw/day orally in the treatment group. T test results on systolic blood pressure (p = 0.00), which was <0.05, showing significant differences in systolic blood pressure in treatment groups. It can be concluded that DLBS1033 can lower systolic blood pressure in wistar rats with induced hypertension using prednisone 1.5 mg/kgbw/day and NaCl 2%.
ANTIBODY ANTI-DENGUE PROFILE IN DENGUE HEMORRHAGIC FEVER PATIENTS AT DR. SOETOMO HOSPITAL, SURABAYA
Authors: Waskito Langgeng A , Notopuro Paulus B , Endraswari Pepy Dwi
Published: December 2017

Dengue hemorrhagic fever is one infectious diseases that have high case fatality rate in Indonesia. The aim of this study was to descibe the antibody anti-dengue profile in dengue hemorrhagic fever patients at Dr. Soetomo Hospital Surabaya. This study was epidemiological descriptive study to aims prevalence primary and secondary infection of dengue hemorrhagic fever and its clinical appearances. This study used 85 samples by taking medical record data of IgM and IgG anti-dengue serologic test from Internal Medicine Department, Dr. Soetomo Hospital, Surabaya, between January to December 2010. The data were collected and analyzed in diagrams and tables. Result of this study showed 25 (29,4%) patients had positive IgM serologic test, 14 (16,4%) patients had positive IgG serologic test and 46 (54,2%) patients had positive IgM and IgG serologic test. In primary infections, the history of fever was 3.8±1.2 days; platelet counts 58,6±21,4/ml and bleeding sign 37% of 25 patients. In secondary infections, the history of fever was 4.28±1.15 days; platelet count was 44,17±24,2/ml and bleeding sign 52% of 60 patients. In conclusion, patients with secondary infection have higher prevalence than primary infection. Then in secondary infection had more severe clinical appearance than primary infection.