bluuebunny/crossref_metadata_2025 huggingface dataset:
Sensory World at Your Fingertips
Authors: Savenko E.I.
Published: January 2023

The article presents a program, the development of which is due to the originality of the emotional-volitional sphere, character, sensory experience of visually impaired and blind students. The program is aimed at reducing psycho-emotional stress, teaching children the skills of psychological self-regulation in a sensory room. A sensory room for a visually impaired and blind child gives an opportunity for the student to mitigate or eliminate their internal problems. Periodic visits by students with visual impairments to the sensory room allows solving the problems of preventing difficulties in learning, upbringing and socialization, deviations in the development and behavior of students. The effectiveness of this program was monitored according to diagnostic data based on the developed criteria before and after the trainees completed the cycle of classes. The implementation of the program revealed a positive trend in personal and social results.
Multiplet analysis at Coso geothermal
Authors: Lees Jonathan M.
Published: January 2023

We have searched the Coso geothermal field (CGF) for microseismicity in seismic doublets, co-located hypocenters that appear to have nearly identical waveforms. Using 1085 high-quality events from 1993 to 1994, we identified numerous doublets, some occurring within minutes of each other. We subdivided hypocentral data into spatial clusters to reduce the computational burden and evaluated multiple cross-correlation pairs, assigning scores to each pair. As an example, one spatial cluster includes 183 events yielding 96 high-correlation (>0.6) paired events. To isolate potential multiplets, equivalence class analysis and cluster analysis routines were used. Among the 96 high-correlation pairs, 24 equivalence classes have been isolated. While most of these are doublets, 8 classes include 3 or more cluster members and one class includes 16 members. Relative locations were calculated using phase shifts between corresponding events. Detailed analysis of hypocenter relocations shows elongate, vertical structure with apparent random temporal variations. The multiplets do not appear to be true repeating events; rather, they are clusters of small, nearly identically oriented ruptures, perhaps representing swarms of fractures activated by fluid-pressure fluctuations. Using the small volumes encompassing each multiplet, we estimate fracture densities measure between 0.02 and 0.4 m−1 and are largest near injection wells.
Computation of differential seismograms for point and plane scatterers in layered media
Authors: Moinet F. , Dietrich M.
Published: January 2023

The first-order scattering effects of elastic waves generated by point sources in layered media are computed using two different geometries and formulations. We first consider point diffractors and demonstrate for elastic scattering Trorey's (1970) result of the equivalence between a specular reflection from a plane interface and a “Kirchhoff” summation of point diffractors in a planar array. We then propose a fast and convenient formulation to calculate the first-order scattering of an infinite slab within a layered elastic medium. Our study shows that the first-order scattering theory is remarkably accurate at angles of incidence not exceeding 35°, and that the formulation used allows us to model density or velocity perturbations of up to 10%. These conclusions are in close agreement with results previously obtained in the plane-wave domain. The methods and expressions presented have implications for Kirchhoff back-projection imaging methods and may be useful in assessing the sensitivity of the seismic response of depth-dependent elastic media to various combinations of elastic parameters. They are also directly applicable to linearized inversion algorithms of seismograms using gradient techniques.
The Main Issues of U.S. Foreign Policy During the 1990s. Importance of Central Europe
Authors: Wordliczek Rafał Grzegorz
Published: January 2023

W wyniku zakończenia zimnej wojny Stany Zjednoczone stały się hegemonem w międzynarodowych stosunkach politycznych. Niniejszy artykuł dotyczy głównych aspektów interesu narodowego USA w ostatniej dekadzie 20 wieku. Jest to analiza głównych założeń polityki zagranicznej USA podczas prezydentur George’a W.H. Busha i Billa Clintona. Deklaracje obu polityków pokazały, że Europa Środkowa i Bałkany są bardzo ważne dla interesów USA. Rzeczywistość polityczna i zaangażowanie USA zweryfikowała te stanowiska. Administracje prezydentów Busha i Clintona umiejscowiły priorytety polityki USA w innych regionach świata: np. w Panamie, Iraku. Dla prezydenta Clintona najważniejsze zadania związane były z rozwojem międzynarodowej współpracy gospodarczej np. z Japonią czy Unią Europejską. Wobec regionu Europy Środkowej i Bałkanów Stany Zjednoczone zaktywizowały się przy procesie rozszerzenia NATO oraz poprzez zaangażowanie dyplomatyczne i militarne w czasie konfliktu na Bałkanach.
The Migration Crisis and the Attitude of the Polish Authorities Towards Migrants in the Context of Opinions Formulated During the Meetings of the Visegrad Group (V4)
Authors: Szkurłat Jacek
Published: January 2023

W artykule poddano analizie stosunek władz polskich do obecnego kryzysu migracyjnego na granicy polsko-białoruskiej, w kontekście komunikatów formułowanych przez przedstawicieli rządu i parlamentu podczas szczytów Grupy Wyszehradzkiej (V4). Poglądy w nich zawarte wskazują na dwie kwestie. Po pierwsze, strona polska zamierza prowadzić działania uniemożlwiające przedostanie się na terytorium naszego kraju imigrantów, nawet jeśli oznacza to w praktyce łamanie prawa międzynarodowego. Po drugie zaś, problemy z przepływami ludności powinny być rozwiązywane przede wszystkim w krajach pochodzenia migrantów i w tych państwach, które leżą na głównych szlakach migracyjnych. Negatywnym tego aspektem jest niestety dehumanizacja imigrantów. Spotkania na forum V4 stają się zatem okazją do przekazywania haseł zarezerwowanych do tej pory głównie na potrzeby polityki wewnętrznej i zdobycia swoistej legitymacji do ich wygłaszania pokazując niejako, że mają one poparcie władz krajów, których wschodnie granice (oczywiście poza Czechami) są jednocześnie granicami Unii Europejskiej, a tym samym Polska nie jest odosobniona w swoich opiniach. W artykule zastosowano metodę monograficzną.
Comparison of Public Diplomacy and Nation Branding of Slovakia and Slovenia
Authors: Řádek Miroslav , Bušša Marián
Published: January 2023

Chociaż dyplomacja publiczna i branding narodowy jako tematy badawcze nie stanowią obecnie istotnego przedmiotu profesjonalnych zainteresowań lub analiz, są nadal aktualne i mogą być stale oceniane, głównie w formie studiów przypadku. W niedalekiej przeszłości powstało kilka prac oceniających różne strategie brandingu narodowego, ale jak dotąd żadna nie dotyczyła brandingu narodowego tak (zewnętrznie) podobnych krajów, jak Słowacja i Słowenia. Część teoretyczna artykułu poświęcona jest zdefiniowaniu podstawowych pojęć oraz wprowadzeniu do stanu aktualnej wiedzy. Część badawcza dotyczy opisu początku i rozwoju niezależnych dyplomacji obu tych młodych krajów. Kolejno omawiane jest tworzenie i wdrażania obu programów brandingowych, a następnie, poprzez analizę treści najważniejszych światowych gazet codziennych, zostaje podjęta próba opisania medialnego wizerunku Słowacji i Słowenii z perspektywy międzynarodowej.
Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
Authors: Montoro J , Antolín-Amérigo D , Izquierdo-Domínguez A , Zapata JJ , González G , Valero A
Published: January 2023

Background: Pressurized metered-dose inhalers (pMDIs) exert an environmental impact resulting from CO2 emissions. Therapeutic alternatives with less environmental impact are widely used. Nevertheless, the choice of device and appropriate therapy should meet the clinical needs and the characteristics of the patient. Objective: The primary objective was to estimate the impact of pMDIs prescribed for any indication on annual CO2 emissions in Spain.The secondary objective was to evaluate the potential impact of switching pMDIs to dry-powder inhalers (DPIs) in patients with asthma. Methods: A systematic review of the evidence published during 2010-2021 was carried out. Average annual CO2 emissions of DPIs and pMDIs were calculated in 2 scenarios: the current situation and a hypothetical situation involving a switch from all pMDIs to DPIs. The impact of the switch on clinical outcomes was also evaluated. Results: The total value of CO2-eq/year due to DPIs and pMDIs accounted for 0.0056% and 0.0909%, respectively, of total emissions in Spain. In the event of switching pMDIs to DPIs, except those used for rescue medication, the percentages were 0.0076% and 0.0579%. The evaluation of efficacy, handling, satisfaction, safety, and use of health care resources was not conclusive. Conclusions: Current CO2 emissions by pMDIs account for a small percentage of the total CO2 footprint in Spain. Nevertheless, there is a need for research into new and more sustainable devices. Suitability and patient clinical criteria such as age and inspiratory flow should be prioritized when prescribing an inhaler.
KOMATIITE LAVAS FROM THE QUEBRA OSSO GROUP (RIO DAS VELHAS GREENSTONE BELT, SOUTHEAST BRAZIL): A FIELD GUIDE TO AN ARCHEAN FLOW FIELD
Authors: Ferreira Raianny Carolini Ramos , Pinheiro Marco Aurélio Piacentini , Magalhães Joana Reis , Novo Tiago Amâncio
Published: January 2023

The Quebra Osso Group encompasses one of the best preserved Archean komatiite flows in the Quadrilátero Ferrífero region, southern São Francisco craton (Brazil). It is commonly associated with the base of the Rio das Velhas greenstone belt within the Santa Bárbara tectonostratigraphic block. The Quebra Osso rocks are well exposed along the valley of the homonymous river, near the Catas Altas city (Minas Gerais state), and in inactive serpentine quarries. In this field guide, we provide the descriptions of the key outcrops in this area, including a variety of komatiite flows, sedimentary rocks and pyroclastic rocks. Despite the pervasive alteration of primary mineral assemblages due to greenschist to amphibolite facies metamorphism, the ultramafic rocks exhibit diverse igneous textures and structures. Volcanic textures are recognizable due to the morphology of the original igneous olivine and pyroxene, which underwent pseudomorphosis by hydrous minerals – serpentine and chlorite. These features include distinctive spinifex and cumulate textures that provide clues of the conditions operating during emplacement and crystallization of the ultrabasic liquids. The predominance of thick-packages of massive flows suggests channelized lava flows, with subordinate thin marginal layered (spinifex-textured), pillowed, brecciated and pyroclastic flows. Volcanic breccias, pillow lavas and chemical sedimentary rocks indicate that these rocks erupted underwater. These multiple volcanic products characterize a unique komatiite flow field and their remarkable preservation distinguishes the Quebra Osso Group from the other ultramafic associations within the São Francisco Craton.
Short and midterm functional and radiological outcomes of revision total hip arthroplasty with uncemented extensively porous coated monoblock cylindrical femoral stems
Authors: Zala Kashyap L.
Published: January 2023

Background: This retrospective cohort study examines clinical and radiological outcomes of revision total hip arthroplasty (THA) using uncemented extensively porous coated mono block femoral stems.
Methods: Patients who were operated for revision THA at medical college Baroda, between January 2008 to December 2018, and who had at least 36 months follow up were included in the study. Details were retrieved from hospital records. Harris hip score (HHS) was used for functional outcome and Paprosky classification was used for femoral bone defects.
Results: Mean age of patients was 60.1 year (range 35-86 years), mean follow up was 84 months (range 40-126 months), Paprosky type 1 defect was found in 4 hips, type 2 was found in 20 hips and type 3a defect was found in 21 hips. Mean HHS improved from pre-operative 30 to post-operative 78 (p=0.0104). Expected survival at 5 and 10 years was more than 95%. No stem was loose at the end of follow up. Thigh pain and proximal osteolysis were most common complications.
Conclusions: Extensively porous coated cylindrical stems give good functional and radiological outcomes at short and midterm follow up.
Effect of Bi2O3 on Physical and Luminescence Properties of Unconventional Bi/Er Co-Doped Sb2O3-WO3-Li2O Glasses
Authors: Bedra Abdelhakim , Soltani Mohamed Toufik
Published: January 2023

New glasses in the system (80-x) Sb2O3-10WO3-10Li2O co-doped with Bi3+/Er3+ were synthesized using the melt quenching method. The Er3+ concentration was kept constant at 0.25 (mol. %) and the Bi2O3 content takes the values 0.5, 1, 1.5 and 2 (mol. %) in order to elucidate the effect of the Bi2O3 concentration on the measured physical and optical properties of the glasses studied. The pulse echo method of the propagation of ultrasound in these glasses has been used to determine the elastic modules (E, G, K and L) and Poisson ratio. The introduction of Bi2O3 in these glasses increases the thermal stability factor of the glass from 152 to 183°C with an increase in Tg from 275 to 285°C. The UV-Vis cutoff of these glasses redshifts from 408 to 413 nm with a reduction of the indirect band gap from 2.72 to 2.62 ev and a small Urbach energy close to 0.125 nm resulting in small electronic defects in these glasses. The refraction index was found high with small variations in the range [1.965-1.975]. The emission spectra of Er3+ ions in these glasses gave an intense green laser line at 544 nm for an excitation at 488 nm. Moreover, the addition of more Bi2O3, considerably improves this laser line. However, the OH content in these glasses increases with the increase in Bismuth content related probably to the introduction of atmosphere moisture during the synthesis of these glasses. Therefore, the addition of Bi2O3 improves the various physical properties of these glasses making them good candidates for optical applications.
Addition Effects of MgO‏ on Structure and Physical Properties in Bi-2212 Ceramics
Authors: Kalkoul Nadira , Boussouf Nora , Mahjoub Saadia , Sahraoui Hadda , Mosbah Mohamed Fayçal , Altintas Sevgi Polat , Koc Nevin Soylu
Published: January 2023

The effect of magnesium on the microstructural and superconducting characteristics of bulk Bi2Sr2CaCu2MgxOy superconductors with x=0 to 0.05 by solid reaction has been examined in this study. Bi2Sr2CaCu2O8+d is formed as the primary phase, and Bi2Sr2CuO6+d (Bi-2201) is present as the parasitic phase, according to XRD data. In doped samples, the c lattice parameter decreases, indicating that Mg has entered the Bi2Sr2CaCu2O8+d crystallographic unit cell. The grain morphology of the samples containing magnesium has changed significantly, and the lamellar structure typical of high temperature superconductors can be seen in the SEM micrographs. The critical temperatures, Tcoff and Tconset, are raised by the addition of Mg, delimiting the superconductive transition. Tconset's maximum value corresponds to x = 0.05.
Fabrication and Mechanical Behaviour Investigation on Aluminium 7075 Boron Carbide and Inconel Alloy 625 Metal Matrix Composite Using Ultra Sonic Stir Casting Method
Authors: Thayumanavan M. , Kumar K.R Vijaya
Published: January 2023

Aluminium metal matrix composites produced using the ultrasonic stir casting method offer important benefits in aerospace and automotive applications. Aluminium composite material utility has recently increased in all engineering sectors due to its high strength, good wear and corrosive resistance. This study was designed to disperse boron carbide and Inconel Alloy 625 reinforced with aluminium 7075. By varying the weight percentages of boron carbide (2wt percent,4wt percent,6wt percent, and 8wt percent) and Inconel alloy 625 (2wt percent,4wt percent,6wt percent, and 8wt percent) for aerospace applications. The scanning electron microscope was used to examine the morphology and distribution of reinforced particles in a synthetic aluminium composite material. It virtually depicts the uniform distribution of reinforcement particles in the base material matrix (Aluminium 7075). To determine the hardness of the hybrid composite material, a Brinell hardness test was performed. It has been discovered that increasing the reinforcement percentage increases the hardness of the synthesised hybrid composites when compared to the aluminium 7075 base matrix material. Mechanical property testing on fabricated composites specimens of various compositions has been carried out.
Ultra-Fine Treated and Untreated Walnut Shell Ash Incorporated Cement Mortar: Properties and Environmental Impact Assessments
Authors: Aadi Ayad S. , Mohammed Ahmed Ali , Mohammed Ali Taghreed Khaleefa , Hilal Nahla N.
Published: January 2023

The utilization of walnut shell (WS) as partial replacement of aggregates and cement is getting more attention in modern research on construction material. Though WS provides lightweight concrete, but less compressive strength and porous structure of concrete is still problematic for its utilization. Thus, this study is using untreated walnut shell powder (UWSP) and ultra-fine treated walnut shell ash (UFTWSA) as a substitute for cement. Different weight fractions of UWSP and UFTWSA (5, 10, 15 and 20%) were used to investigate the influence on fresh and hardened properties of cement mortar. Further, the durability of all mixes was evaluated by immersing them in different concentrations of MgSO4 (5, 10 and 20%). The experimental results revealed that the inclusion of UWSP and UFTWSA reduces the fresh and hardened properties of cement mortar. Moreover, UWSP addition has more negative impact on fresh and hardened properties of cement mortar as compared to UFTWSA. The hardened properties of mortar specimens remarkably decreased by immersing in MgSO4 solution. However, all mixes contained UWSP and UFTWSA and not exposed to acid attack achieved more than 30 MPa and can be classified as good type mortar depending on obtained ultra-sonic plus velocity values (UPV).
Comparative Analysis of Deep Learning Models on Brain Tumor Segmentation Datasets: BraTS 2015-2020 Datasets
Authors: Aggarwal Mukul , Tiwari Amod Kumar , Sarathi M. Partha
Published: January 2023

Deep Learning neural networks have shown applicability in segmentation of brain tumor images.This research have been carried for comprehensive review of several deep learning neural networks. The datasets included in this study are standard datasets Multimodal Brain Tumor Segmentation (BraTS). This paper has summarized the performance of various deep learning neural network algorithms on BraTS datasets. Algorithms have been compared and summarized against the baseline models with specific attributes like dice score, PPV and sensitivity. It has been found that out of the different models applied on the BraTS 2015 dataset GAN in the year 2020 algorithm is showing better results on this data set. GAN architecture termed RescueNet gave the best segmentation results in terms of 0.94 dice score and 0.88 Sensitivity. This has been also observed that models used cascaded deep learning models had independent deep learning models at each stage which had no correlation among the stages which can cause class imbalance. Further it have found that the Attention models tried to solve problem of class imbalance in the brain tumor segmentation task. This work also found that existing CNN’s is having overfitting issues. For this ResNet models can add a rapid connect bounce relationship parallel to the layers of CNN to accomplish better outcomes for the brain tumor segmentation task.
Multi Label Automatic Image Annotation Neural Network to Handle Multi Media Image Retrieval
Authors: Kunisetti Subramanyam , Ravichandran Suban
Published: January 2023

The present-day business online web indexes have embraced electronic picture search to further develop precision in picture information recovery. However Re-positioning is expectedly considered as a successful cycle for deciding the situation with electronic picture web search tools, yet it experiences a lack of a couple of. Consequently, some grouping methods, particularly (Novel Image Re-positioning System) NIRS have to be proposed to carry out inquiry picture re-positioning with semantic marks in electronic picture information recovery, which naturally recovers results in view of visual semantic highlights for various question or catchphrase extensions. To get to productive picture with the annotation is an aggressive concept in present. So that in the present paper, we are going to propose the Unsupervised Multi Labeled Image Annotate Learning Approach (UMLIALA) to decrease complexity in indexing of image with mining of web related convex optimization and classify required image data from large image data sets. And also use group based approximation calculation to improve accuracy in retrieval of images from different image data sources. Experiments of proposed approach give better and efficient results when compare to traditional approaches in terms of different image exploration parameters studies on different large image data sets.
Women, Peace, and Security Norms as seen by Norwegian Male Officers
Authors: Bæk Sindre , Skjelsbæk Inger
Published: January 2023

This article explores how male officers in the Norwegian Armed Forces (NAF) understand the relevance of the global Women, Peace, and Security (WPS) norms in their conceptualizations of security work. The study is based on in-depth interviews with 13 Norwegian male officers, draws on a discourse theoretical framework, and feeds into scholarly discussions on security, gender, and diversity. The findings indicate that the WPS norms are seen primarily as tools for improving military overseas operations, and further, that gender equality is seen as a ‘natural’ part of Norwegian identity, including the professional identities of military personnel in the NAF. WPS norms are therefore perceived as less relevant at home than abroad. We argue that this is because the attitudes toward gender issues that the officers regard as ‘natural’ interact with other gender roles and cultures in overseas operations, and therefore pertain to distant ‘others’ more than to the ‘self ’.
“SELF-IMAGE” OF TRAFFIC POLICE OFFICERS: THE CONCEPT AND SOME ASPECTS OF ITS FORMATION
Authors: Lozhkina Natalia
Published: January 2023

psychological experiment and observation, questionnaire and testing, interview and survey, expert evaluation, methods of processing and statistical analysis of experimental data (methods of computer data processing, graphical and tabular interpretation of results, methods of mathematical statistics, correlation and factor analysis), which confirmed the positive dynamics of the formation and development of the “Self-image” of a traffic police officers.

Results. The article analyzes the process of forming the “Self-image” of traffic police officers, which significantly affects the quality of professional training and official behavior. In the context of this process, the problem of the negative influence of public opinion and ways to neutralize it through the formation of a positive “Self-image” of traffic police officers is being considered.

Research implications. The article describes the empirical data obtained, revealing the socio-psychological mechanisms of the influence of public opinion on the formation of the “Self-image” of traffic police officers, and the essential signs and features of its formation.
Renal artery stenosis: a single center experience
Authors: AYAR Yavuz , DÖNER Barış , AKGÜR Suat , İŞLEYEN Mustafa , OCAKOĞLU Gökhan
Published: January 2023

Objectives: Renal artery stenosis (RAS) is among the most common causes of secondary hypertension. Prevalence of RAS are seen in end-stage renal disease (ESRD) patients with hypertension between 1-10%. In our study, we evaluated the data of patients with RAS who were followed up with medical treatment and stenting.
Methods: In our study, patients who were thought to have renal artery stenosis (RAS) with renal artery doppler ultrasonography were scanned with contrast-enhanced Magnetic Resonance Angiography (MRA). Fifty-three patients (10 received medical therapy, 43 applied invasive procedure) who diagnosed with RAS evaluated.
Results: Follow-up times were 15 (12-84) months in patients who received medical therapy, and 12 (10-96) months in patients who treated with invasive therapy (p = 0.583). Median ages were 56 (19-74) years in medical treatment group, and 60 (15-77) years in invasive therapy group (p = 0.955). Compared with the beginning of treatment, diastolic hypertension was decreased of 12.5% in invasive treatment group opposite medical therapy group (p = 0.040), so eGFR was increased of 5.94% in invasive treatment group.
Conclusions: In recent years, several studies about survival in patients with RAS was observed that there was no significant difference between the medical and invasive treatment. Clinical, laboratory, and individual characteristics should be considered in treatment choice.
Biochemical and molecular genetic markers of kidney damage in hypertension
Authors: Spiridonov A. N. , Khudiakova A. D. , Striukova E. V.
Published: January 2023

This review presents the results of research in the field of studying associations of biochemical and molecular genetic markers of kidney damage in arterial hypertension. Information on the topic from publications of PubMed, Google Scholar databases was used.
The role of the rs2297518 of NOS 2 gene as a genetic biomarker of arterial hypertension and “arterial hypertension and tension-type headache” phenotype (the pilot study in East Siberia)
Authors: Alyabyeva P. V. , Reznichenko P. A. , Shnayder N. A. , Kaskaeva D. S. , Petrova M. M.
Published: January 2023

Nitric oxide (NO) plays an important pathogenetic role in vascular relaxation and is a candidate molecule of a common pathogenetic link in the development of arterial hypertension (AH) and tension-type headache (TTH).

Objective of the study was to study the association of the single nucleotide variant (SNV) rs2297518 of the NOS 2 gene with the risk of developing AH and clinical “AH + TTH” phenotype in adults living in a large industrial city of Eastern Siberia.

Design and methods. All participants (N = 91) were divided into two groups: group 1 (patients with AH) — 60 people, including the main subgroup (patients with AH without headache) — 30 people and a comparable subgroup (patients with clinical phenotype “AH + TTH”) — 30 people; group 2 (control — healthy volunteers) — 31 people. Carriage of the SNV rs2297518 gene NOS 2 (locus 17q11.2) was determined using real-time polymerase chain reaction.

Results. The minor allele A rs2297518 of the NOS 2 gene was statistically significantly associated with a high risk of developing AH (odds ratio (OR) = 8,43 [95 % confidence interval (CI): 2,33–30,46], p = 0,000223) and phenotype “AH + TTH” (OR = 5,44 [95 % CI: 1,46–20,21], p = 0,006) compared with the control group. The heterozygous genotype GA rs2297518 of the NOS 2 gene also was statistically significantly associated with a high risk of developing AH (OR = 8,17 [95 % CI: 2,03–32,79], p = 0,001).

Conclusions. The study demonstrated that the minor allele A of the SNV rs2297518 (26096597 G > A) of the NOS 2 gene, which encodes the inducible NO-synthase (iNOS), can be considered as a clinically significant genetic biomarker, first of all, of AH in the Caucasian population of Eastern Siberia. At the same time, future studies may clarify the role of this SNV as a genetic biomarker of the “AH + TTH” phenotype.
Influence of a new stimulator of soluble guanylate cyclase on platelet aggregation and vascular endothelial function in experimental ischemic stroke against the background of arterial hypertension
Authors: Bykov V. V. , Bykova A. V. , Aliev O. I. , Stankevich S. A. , Khazanov V. A. , Vengerovsky A. I. , Udut V. V.
Published: January 2023

Background. Correction of endothelial dysfunction during arterial hypertension (AH) is an important measure in preventing cerebrovascular stroke. Drugs activating soluble guanylate cyclase (sGC) and 3’,5’-guanosine monophosphate (cGMP) production independently of nitric oxide (NO) were shown to be therapeutically useful in reducing the risk of stroke. The present work aims to study the antiaggregant and endothelium-protective activity of a new sGC stimulator, an indolinone derivative (2-[2-[(5RS)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidine-2- yliden]-2-cyanoethylidene]-1H-indole-3(2H)-one (codename — GRS) in a model of ischemic stroke with AH. Prior studies have shown that GRS compound inhibits platelet aggregation, lowers blood pressure (BP) in spontaneouslyhypertensive SHR rats, prevents vascular occlusion in models of arterial and venous thrombosis. Antiplatelet drug clopidogrel, a P2Y12 receptor inhibitor, included in the standard of care for secondary prevention of ischemic stroke, was used as the reference drug.

Objective. To assess the antiaggregant and endothelium-protective activity of a new indolinone derivative GRS, an sGC stimulator, compared to clopidogrel in a model of ischemic stroke concomitant with high arterial BP in spontaneously-hypertensive SHR rats.

Design and methods. Focal brain ischemia/reperfusion was modelled in spontaneously-hypertensive SHR rats (n = 78). GRS in 10 mg/kg dose and clopidogrel in 10 mg/kg dose were administered orally once daily 3 days before modelling ischemia/reperfusion and for 5 days afterwards. Platelet aggregation and functioning of vascular endothelium were monitored.

Results. Focal brain ischemia/reperfusion in SHR rats resulted in increased platelet aggregation and the development of endothelial dysfunction and disruption of vasodilatory function of endothelium. GRS compound and clopidogrel in repeated administration have prevented an increase in platelet aggregation (p < 0,05), GRS compound also alleviated endothelial dysfunction (p < 0,05).

Conclusions. The indolinone derivative GRS, an sGC stimulator, inhibits increased platelet aggregation and prevents endothelial dysfunction in rats after focal brain ischemia/ reperfusion; the endothelium-protective effects of GRS aren’t related to its antiaggregant activity.
Laying Bare: Agamben, Chandler, and The Responsibility to Protect
Authors: Quigley Gabriel
Published: January 2023

This paper demonstrates the hidden similarities between Raymond Chandler’s prototypical noir The Big Sleep, and the United Nations Responsibility to Protect (R2P) document. By taking up the work of philosopher Giorgio Agamben, this paper shows that the bare life produces the form of protection embodied by Philip Marlowe in Chandler’s novel and by the United Nations Security Council in R2P. Agamben’s theorizing of the extra-legal status of the sovereign pertains to both texts, in which the protector exists outside of the law. Philip Marlowe, tasked with preventing the distribution of pornographic images, commits breaking-and-entering, withholding evidence, and murder. Analogously, R2P advocates for the Security Council’s ability to trespass laws that safeguard national sovereignty in order to prevent “bare” atrocities against human life. As Agamben demonstrates, the extra-legal position of the protector is made possible by “stripping bare” human life. This paper also gestures towards limitations of Agamben’s thought by indicating, through a comparison of these two texts, that bare life produces states of exception as the object of protection rather than punishment.
“Reread me backwards”: Deciphering the Past in Elizabeth Bowen’s The Heat of the Day
Authors: Johnson Stephanie
Published: January 2023

Set during the midst of the London Blitz, Elizabeth Bowen’s The Heat of the Day revolves around a narrative of espionage, but unlike many novels from the spy genre, it refuses to disclose all of its secrets. Instead, the novel’s dense and complex language, which so effectively expresses the dislocating effects of a city under attack, resists an easy or uncomplicated reading. This article examines the motif of reading within the novel, which manifests when its protagonist, Stella Rodney, learns her lover Robert is a Nazi spy. In her efforts to locate proof of his defection, Stella becomes caught in a recurrent but indeterminable task of rereading past events, a movement which attempts to remember the past but also foregrounds a fundamental inability to ever wholly resolve its enigmas. When Stella fails to read her past for lost clues, she is prevented from viewing the events of her life as a coherent and meaningful narrative. The novel’s difficult language reflects this lack of resolution, refusing to assimilate the events it depicts into a straightforward account. With its wartime setting as a disorienting backdrop, The Heat of the Day undermines the purpose of reading as the discovery of sense and meaning, producing instead only more questions and mysteries.
Sample application on dramatization in education
Authors: Yurtay Yuksel , Yurtay Nilüfer , Yuksel Arda , Armay Ayca
Published: January 2023

Developments on the technology have a big effect to change our lifestyle and education methods. It is obvious that effects of games based computer technology is increased on peopleâ€™s life. Dramatization in Education is the one of the latest studies that is used education materials and dramatization methodologies. The idea of converting the education materials to game, is invented with changing human profiles and their interestsIn these study, it is intended that teaching the Gini Algorithm that is used with dramatization tools which is the one of the most significant usage area in data mining. The dramatization of theorical steps of Gini Algortihm is executed and it is developed with practiced on a group of student. It is measured the effects on students of classical education and dramatization on education with this application.After the measurement, results are discussed, evuluated and shared. The application is designed for mobile devices and it is coded to be used with Android Operating System. Besides, this applicaton is developed computer engineer students based. Instead of to memorize the theroical informations and formulas, the application focused on how people understand the logic.This information becomes permanent information in young minds. Application consists two stages. First one is the preparing of dataset and second stage is the operating the algorithm with the help of prepared datasets and formulas. In the last part of the application, whole main nodes provide to users as decision tree table. Keywords: Education, dramatization, data mining, gini algorithm.
Estimating of student success with artificial neural networks
Authors: Demiralay Raziye , Akdenizli Ibrahim , Boztoprak Halime
Published: January 2023

Purpose of the study is classifying studentsâ€™ success of Information and Communication Technology-ICT courses by using Artificial-Neural-Networks-ANNs models. To classify success of 161 students, a three-layer-feed-forward-ANNs model is used. 3 parameters which contain demographic data and 27 parameters which contain ICT-Usage data captured by a questionnaire chosen as input layer parameters. Hidden nodes are determined experimentally. Logic-0 and Logic-1 are the output level values which define success of the students in ICT courses. The Back-Propagation algorithm is used for training of ANN. The mean squares of the errors are used as a performance (error) function with its goal set to zero. In conclusion, the application done with success ratio of 96%. If same variables are used, realistic estimations will be reached. It is recommended that a research with same parameters would be better results with higher participation. Keywords: Artificial Neural network, backpropagation, student success, classification, ICT.
Designing blended learning environments organized within the basis of web-assisted modeling in science teaching
Authors: Cetinkaya Murat
Published: January 2023

A great number of studies on â€œMatter and Heatâ€ unit have reported that many students have conceptual errors. Studies have shown the necessity of designing and using effective teaching methods in solving such problems. ASSURE teaching design model, which aims to increase the efficiency of material choice and use with systematic prior planning of teaching, was used in creating the materials which were prepared based on web-assisted modeling. In designing blended learning environment, web-assisted activities were used which included mental models as well as analogical and simulation models based on the outcomes of the 6th grade â€œMatter and Heatâ€ unit. The purpose of this study is to design blended learning environments which are designed based on web-assisted modeling for â€œMatter and Heatâ€ unit. Keywords: Science education, web supported teaching, matter and heat, achievement.
Program "Cultural Heritage" - innovation of archeology, history and art in the context of the development of education in the Republic of Kazakhsta
Authors: Kariyev Yeldos Maksatovich
Published: January 2023

The research paper deals with innovations brought about in educational programs bythe national strategic program "Cultural Heritage" (2004-2011), developed for studying, restoring and keeping the historical and cultural heritage of the country; reviving historical and cultural traditions; propaganda of material and spiritual heritage of the Republic of Kazakhstan abroad. The programâ€™s contribution to the development of secondary and higher education in the country is estimated on the basis of comprehensive analysis of the results of various studies which have contributed to the formation of innovation in educational processes of Kazakhstan in the context of Eurasia. All this is made through identification of common trends in various scientific studies on humanitarian grounds, review of similar research in the world. The main chronological range of historical processes reconstructed for implementation into educational programs, is determined from the Paleolithic era to the ethnographic present. Keywords: Humanities, innovations in education, archeology, culture and art, ancient and medieval history of Eurasia, national program "Cultural Heritage".
The effect of teaching supported by interactive whiteboard on studentsâ€™ mathematical achievements in lower secondary education
Authors: Tunaboylu Ceren , Demir Ergul
Published: January 2023

There are some researches about using interactive whiteboard in teaching-learning process, which has become the reflection of technology in the classes. These researches indicate that using interactive whiteboard has many positive impacts on studentsâ€™ affective characteristics such as motivation, attitude and self- efficacy. On the other hand, there are fewer and limited studies about its effects on the success. In this context, the aim of this study is to investigate the effect of using interactive whiteboard in mathematics teaching process on the 7thgradestudentsâ€™ achievement. The study was conducted as experimental design. Experimental and control groups were composed of 58 7thgrade students from one school in the 2015-2016 educational year in Ankara. As a measurement tool, an achievement test developed by the researchers was used as the pre-test and post-test. An education program which included the activities with interactive whiteboard was developed by researchers. And, this program was implemented to the experimental group 12 hours over 3 weeks. On the other hand, activities for the control group were limited to the blackboard usage. In the analysis of the data, â€œanalysis of covariance (ANCOVA)â€was used by defining the pre-test scores as 'covariate' variable. According to the findings, it was observed that there was significant difference between experimental and control groups pre-test average scores [F(1, 55)=12.886, p=0.001<0.05]. When the difference of pre-test scores under control, it was observed the significant difference between the average post-test scores in favour of experimental group [F(1, 55)=9.69, p=0.003<0.05]. These findings show that using interactive whiteboard in mathematics teaching process has positive effects on the studentsâ€™ mathematical achievement. These results are supported by some other researchesâ€™ findings, Archeology, Culture and Art, Ancient and Medieval History Of Eurasia, National Program "Cultural Heritage". Keywords: Education technology, interactive whiteboard, mathematical achievement.
The evalaution of the EBA Portal in terms of learning objects
Authors: Yalcin Nursel , Kilic Berker
Published: January 2023

The Ministry of Education has performed projects named â€œ Connecting all schools to the Internetâ€ and â€œ Setting an Information Technologies Classroom for each schoolâ€ regarding transition of constructivist education curriculum. Within the scope of a number of Project activities named â€œThe Movement of Increasing Opportunities, Improving the Technologyâ€ known for its acronym â€œFATÄ°Hâ€, the ministry have been conducting the operations of using smart boards in classrooms instead of using classical blackboards and delivering the tablet PCs to the students instead of using coursebooks nowadays. In the context level of these operations which are mainly on hardware, the setting of context portal named EBA takes place.In this operation the necessity for the identification of computer aided educational materials broadcasting via EBA portal as the learning objects and associated with the curriculum has been presented. Answers for the questions of whether the educational materials can be associated with the acquisitions taking place in the curriculum during or after the loading process, and whether the metadata of a learning object can be identified are sought in this study. Keywords: Learning object, education portal, material developing, curriculum.
Do trainers pay enough attention to posture adjustment when athletes perform strength exercises in a leg press machine?
Authors: Castaner Marta , Novatchkov Hristo , Orejon Ruben , Vilas Desiree
Published: January 2023

The aim of this study was to analyse trainersâ€™ appraisal of body posture adjustment -specifically joint alignment and flexion/extension of the legs- in athletes performing a leg press exercise. Ten strength trainers observed 15 video records of 15 athletes with no musculoskeletal problems. Kinematic analysis was based on motion capture data from athletes, combined with data from the semantic differential that trainers used to appraise joint alignment and flexion/extension. Multiple analysis of the two kinds of data showed that trainersâ€™ appraisals did not always coincide with what the kinematic parameters indicated regarding the athletesâ€™ posture adjustment while performing the leg press exercise. Keywords: Leg press; posture adjustment appraisal; flexion parameters; flexion adjustment appraisal.
Haematic Potentials of Rhynchospore Corymbosa and Olax Subscorpioïdea Extract in Phenylhydrazine – induced Anaemic Rats
Authors: Soro M’béfèhê , Akakpo-Akue Joël , Ackah Jacques Auguste Alfred Bognan , Sibri Jean-François , Yapi Yayé Guillaume , Kple Tatiana Kangah Mireille , Sanko Sihi Ephrem Léangeovers Getheme
Published: January 2023

The decoction of the whole plant of Rhynchospora corymbosa and Olax subscorpioïdea leaves are used by the Local traditional healers in the department of Korhogo (Northern Côte d’Ivoire) to treat patients with sickle cell disease. This study was designed to assess, the antianemic potential of these plants extract. Anemia was induced with phenylhydrazine hydrochloride in rats. Animals were divided in normal (N), control (C), test (T), and reference (R) groups. T group included ill-induced Animals treated with R. corymbosa and O. subscorpioidea extracts, and R group ill-induced animals treated with vitamin B9 for anemic animals. Dosing was made as 1-day single dose repeated dose. In anemic animals, the production rate of RBC was significantly (p < 0.001) higher in T group as compared to C group. R. corymbosa whole plant and O. subscorpioidea leaves extracts have a haematic potential. The anti-anaemic effect may partly explain their use in patients with sickle cell disease who are affected by a deficiency of erythrocytes and its components.
Effet des Substrats à Base de Déchets Sylvicoles et Gricoles sur la Croissance et le Développement des Semis de Terminalia Invorensis en Pépinière Forestière à Daloa (Centre Ouest de la Côte D’ivoire)
Authors: Raymond Kouame Adou Pangny , Noël Groga , Noel Vouhy Bi
Published: January 2023

Cet article présente les résultats d’un essai conduit au niveau de la ferme expérimentale de l’université jean Lorougnon guède de Daloa visant la production et l’évaluation des caractéristiques agronomiques du compost à base de déchets sylvicoles (sciure de bois) et agricoles (coque de café, coque de cacao, bouse de vache et fiente poulet) pour la production de plants de Terminalia ivorensis. A cet effet, après élaboration du compost, quatre substrats à base de compost et un témoin à base de terre local ont été confectionnés, caractérisés du point de vue physique et chimique et mis à l’essai en pépinière. Les plants étaient suivis à travers les mesure des paramètres de croissance végétale (la hauteur et le diamètre des tiges, le nombre de feuilles, la surface foliaire). Les résultats obtenus montrent que les déchets sylvicoles et agricole présente une bonne aptitude au compostage, son compost peut être facilement produit avec ou sans stimulateur. Le comportement des plants des cinq substrats montre par ailleurs, que des améliorations qualitatives significatives ont été enregistrées chez les plants élevés dans les substrats à base de compost par rapport aux plants du témoin. Les plants élevés dans le compost affichent des gains significatifs de croissance allant de 37,57 à 100 % en hauteur, de 16,8 à 100 % en diamètre. Il est donc possible d’améliorer la qualité des plants de Terminalia ivorensis grâce à l’utilisation de compost de déchets sylvicoles et agricoles comme substrat de culture en remplacement de substrat minéral (terre local).
Aspects Paracliniques et Étiologiques des Ascites au CHUSC de Bangui
Authors: Youssouf Oumarou , Mozane Roland Evrard Felema , Boua Natalie Akélélo , Police Serge Magloire Camengo , George Service , Siolo Barbara Épouse
Published: January 2023

Introduction : l’Ascite est un signe clinique très fréquent en en hospitalisation dans le service d’hépatogastroentérologie et de la médecine interne. Les étiologies sont nombreuses. Objectif : contribuer à une meilleure prise en charge de l’ascite à Bangui. Patients et méthodes : nous avions réalisé une étude transversale descriptive pendant 30 mois dans le service d’hépatogastroentérologie du CHUASC (Centre Hospitalo-universitaire de l’Amitié Sino-Centrafricaine de Bangui). Les patients de deux sexes hospitalisés pour ascite chez lesquels le diagnostic étiologique était connu. Résultats : Pendant la période d’étude, 1210 patients étaient hospitalisés dont 204 présentaient une ascite (16,85%), parmi lesquels 170 (14,9%) avaient répondu à nos critères d’inclusion. L’ascite était pauvre en protéine (˂ 25 g/l) dans 136 cas (80%) et riche en protéine (˃ 25 g/l) dans34 cas (20%).La moyenne des Globules Blancs dans le liquide d’ascite était de 76,94 éléments blancs/mm3 avec des extrêmes de 39 et 678/mm3. Le portage du VHB (virus de l’hépatite B) était plus fréquent dans 67 cas (39, 40%).Le foie remanié était plus fréquent dans 108 cas (63,5%). Les étiologies de l’ascite les plus fréquentes étaient la cirrhose décompensée dans 138 cas (81,17%), Les sujets de sexe masculin étaient plus exposés à la cirrhose décompensée sur le mode ascitique.la carcinose péritonéale dans 15 cas (8,8%) et la tuberculose péritonéale dans 12 cas (7,1%). La cause plus fréquente de la carcinose péritonéale était le Carcinome Hépatocellulaire dans 13 cas (7,65%). Les principaux facteurs de risque étaient le Virus de l’Hépatite B retrouvé dans 55 cas (32,5%) et la consommation d’alcool dans 130 cas (76,5%). Conclusion : les ascites sont d’étiologies cirrhotique associées au virus de l’hépatite B et les hommes sont plus concernée, une politique de vaccination universelle contre le VHB est nécessaire et prometteuse.