bluuebunny/crossref_metadata_2025 huggingface dataset:
Mania Associated with Clonazepam
Authors: Dorevitch Abraham
Published: June 2017

Clonazepam is a potent, long-acting benzodiazepine approved for use in myoclonic and petit mal seizures. Initial reports have demonstrated encouraging results with clonazepam in the treatment of acute mania as well as a favorable side-effect profile. A trial of adjunctive clonazepam was initiated in a 41-year-old patient with chronic schizophrenia. Two weeks later, while on an 8-mg dosage, he became manic, developing pressured speech, euphoria, inflated esteem, agitation, and insomnia. Initiation of electroconvulsive therapy with gradual tapering and discontinuation of the clonazepam resulted in amelioration of the manic episode and a return to his previous clinical status. Clinicians should be alerted to the potential of clonazepam to cause manic-like behavior in susceptible patients.
Urinary Retention Associated with Ipratropium Bromide
Authors: Pras Elon , Stienlauf Shmuel , Pinkhas Jack , Sidi Yechezkel
Published: June 2017

A 69-year-old man was hospitalized for exacerbation of chronic obstructive lung disease. Treatment with nebulized ipratropium bromide resulted in urinary retention that resolved once the drug was discontinued. Urinary retention is a rare complication of ipratropium bromide. Because all of the cases described in the literature occur in elderly men with prostate hypertrophy, the drug should be used cautiously in this group of patients.
Amantadine Neurotoxicity in a Pediatric Patient with Renal Insufficiency
Authors: Strong Dawn K. , Eisenstat David D. , Bryson Scott M. , Sitar Daniel S. , Arbus Gerald S.
Published: June 2017

Amantadine hydrochloride, a dopamine agonist with antiviral and antiparkinsonism properties, is used for the prevention and treatment of influenza A respiratory infections in high-risk populations. The occurrence of amantadine-induced hallucinations and tremors is described in a young, renal transplant patient with declining renal function. Following discontinuation of amantadine, plasma amantadine concentrations were correlated with central nervous system toxicity. In view of the usage of amantadine in renal transplant recipients and the elderly, clinicians must be alert to the possibility of amantadine-induced neurotoxicity in patients with changing renal function.
Hypotension and Bradycardia Possibly Associated with Intraocular Injection of Acetylcholine
Authors: Erickson Steven R. , Yousuf Mohammad J.
Published: June 2017

Topically applied drugs are an important part of the pharmacologic management of cataract extraction and lens implant surgery. Acetylcholine facilitates this procedure via its miotic effect on the ciliary body of the eye. Systemic effects can occur with topically administered ophthalmic medications. Acetylcholine has been implicated in several cases of systemic cholinergic effects, such as hypotension, bradycardia, and bronchospasm, following intraocular administration. The patients we present experienced profound hypotension and bradycardia occurring up to 45 minutes after intraocular injection of acetylcholine. Both patients were over 90 years of age and had a history of first-degree atrioventricular block. As cataract surgery and lens implantation become more prevalent in the older ambulatory segment of the geriatric population, healthcare professionals should be aware that these patients may be more sensitive to the pharmacologic effects of medication used during surgery. Monitoring for adverse effects must be performed intraoperatively and several hours postoperatively. Additionally, patients with known conduction abnormalities prior to surgery should be monitored closely and proper emergency equipment and personnel should be available. Pharmacists who investigate adverse drug reactions should consider ophthalmic medications as potential causes for unexplained or suspected adverse drug reactions.
Ofloxacin during the Second Trimester of Pregnancy
Authors: Peled Yoav , Friedman Shmuel , Hod Moshe , Merlob Paul
Published: June 2017

Ofloxacin can cause retarded ossification and arthropathy in young animals, but there is no published information about its teratogenicity in humans. A 36-year-old woman was treated with ofloxacin 200 mg bid for 6 days during the 19th week of gestation. Ultrasound follow-up of the measurements and structure of the fetal long bones revealed no abnormalities. The neonate's physical examination and X-rays of the chest and long bones were normal. Although no teratogenic or toxic effects were observed in this patient, the use of ofloxacin in human pregnancy should only be a clinical consideration until sufficient evidence regarding its safety in the human fetus has been published.
Naproxen-Induced Recurrent Aseptic Meningitis
Authors: Weksler Babette B. , Lehany Anne Marie
Published: June 2017

Aseptic meningitis has been linked to treatment with several nonsteroidal antiinflammatory drugs (e.g., ibuprofen, tolmetin, sulindac), particularly in patients with disturbed immunity. Naproxen, however, has only once been reported to cause meningitis. We report a case of recurrent aseptic meningitis related to prolonged naproxen usage in a 38-year-old woman with longstanding, minimally symptomatic systemic lupus erythematosus (SLE). Two years after starting naproxen, she experienced three separate episodes of meningitis within a period of 10 months; each episode was preceded by resumption of naproxen administration or an increase in drug dosage. There was no clinical or serologic evidence for the flare-ups of her SLE. Discontinuation of naproxen was followed by prompt recovery once the relationship of the drug to her symptoms was realized. Off the drug, the patient has remained free of meningeal symptoms for more than 18 months. Nonsteroidal antiinflammatory agents should be considered as possible causal agents in evaluating meningitis of obscure etiology.
The Safety, Efficacy, and Tolerability of Cefuroxime Axetil Suspension in Infants and Children Receiving Previous Intravenous Antibiotic Therapy
Authors: Reed Michael D. , Powell Dwight A. , Nahata Milap C. , Powell Nancy E. , Ossi Michael J.
Published: June 2017

The tolerability, safety, and efficacy of cefuroxime axetil suspension was studied in 36 children (aged 3 mo to 12 y) who had been hospitalized for respiratory tract or soft-tissue infections. After receiving parenteral antibiotics for a mean of 3.7 days, children were discharged home to receive cefuroxime axetil suspension at doses of 10, 15, or 20 mg/kg every 8 or 12 hours for a mean of 8.2 days. One child was lost to follow-up. Three of 35 evaluated patients were withdrawn from therapy because of adverse events, one of which was a drug-related hypersensitivity reaction. Of the 32 children who completed therapy, 9 developed mild reactions including oral thrush, diarrhea, or diaper dermatitis; none were withdrawn from therapy. Complete clinical cure occurred in 28 children (80 percent); 4 (11.4 percent) were clinically improved but still required an additional antibiotic within one week of completing therapy with cefuroxime axetil suspension. This favorable tolerability and safety of cefuroxime axetil suspension warrants further efficacy trials in pediatric patients.
Work Group Collectivism and the Centrality of Work A Multinational Investigation
Authors: Hattrup Keith , Ghorpade Jai , Lackritz James R.
Published: June 2017

This study examined relationships at the individual level of analysis between work group collectivism and work centrality and pride in work, and the moderating effects of nations on these relationships. Participants from Ecuador, Germany, India, Mexico, and the United States completed questionnaire measures of the constructs of interest. Multiple-groups confirmatory factor analyses were performed to evaluate and control for psychometric nonequivalence in the measurement of latent constructs, prior to multiple-groups structural equation modeling analyses of the relationships between work group collectivism and work centrality and pride in work. Results showed positive relationships between collectivism and work centrality and work pride in each country, and non-significant differences between countries in these relationships. Tests of mean differences at the nation level of analysis also showed somewhat higher work centrality and pride in work among countries that scored higher in work group collectivism.
Customs Associated with Premarital Sexual Freedom in 143 Societies
Authors: Barry Herbert
Published: June 2017

In a world sample of 143 diverse societies, partial correlations and a multiple regression demonstrated that seven customs each had an independently statistically significant association with a high degree of premarital sexual freedom. Three customs, which support independence of marital couples, are minimal government hierarchy, no payment at marriage, and pigs are the largest domesticated animals. Four customs, which support community cooperation, are ceremonial praying, matrilineal kinship, exogamous marriage, and a high degree of community integration. Within the past century, premarital sexual intercourse has become more permitted in many industrialized nations. This change may be partly attributable to more independence of marital couples and cooperation in more widespread communities.
Dinutuximab in the Treatment of High-Risk Neuroblastoma in Children
Authors: Gur Hazal , Ozen Fatih , Can Saylan Cemil , Atasever-Arslan Belkis
Published: June 2017

Neuroblastoma is the most common extracranial tumor derived from neural crest cells in childhood, and treatment of high-risk neuroblastoma is a difficulty in oncology field. The discovery of new treatment strategies to treat pediatric patients with high-risk neuroblastoma is important. Dinutuximab (ch14.18; Unituxin), a chimeric human-mouse monoclonal antibody, is approved by Food and Drug Administration in 2015 to be used specifically in the treatment of high-risk neuroblastoma. It binds the disialoganglioside (GD2) antigen on the surface of neuroblastoma cells and induces lysis of GD2-expressed neuroblastoma cells via antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity. To enhance its activity, it is used with a combination of granulocyte-macrophage colony-stimulating factor, interleukin 2, and 13- cis-retinoic acid. In this review, we discuss the use of dinutuximab in the treatment of high-risk neuroblastoma.
Current Treatments in the Management of Idiopathic Pulmonary Fibrosis: Pirfenidone and Nintedanib
Authors: Hayton Conal , Chaudhuri Nazia
Published: June 2017

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease associated with significant morbidity and mortality. Historically, IPF has been managed using combination immunosuppressive therapy; however, this has been shown to be associated with increased mortality. Over the past 5 years, 2 disease-modifying agents have been licensed for use in IPF. Pirfenidone is a novel therapy with antifibrotic and anti-inflammatory properties. Evidence from a number of randomised control trials has shown that pirfenidone slows the progression of decline in forced vital capacity in IPF. Nintedanib is a tyrosine kinase inhibitor with antifibrotic properties which has also been shown to significantly reduce disease progression. As head-to-head comparison data are lacking, treatment selection is based on patient and clinician preference and tolerability of side effects. In the future, combination therapy with pirfenidone and nintedanib or with additional therapies may further improve lung function preservation.
Advances in Chronic Obstructive Pulmonary Disease Therapy: A Vascular-Targeted Approach
Authors: Okpechi Samuel C , Ghonim Mohamed A , Lammi Matthew R
Published: June 2017

Chronic obstructive pulmonary disease (COPD), a common, preventable, and treatable disease characterized by persistent respiratory symptoms and airflow limitation, is rapidly becoming a global healthcare challenge. Chronic obstructive pulmonary disease is the third leading cause of death in the United States and has been ranked fourth worldwide. Its current therapies improve symptom relief but do not alter the natural history of the disease. Therefore, as COPD is a progressive condition, novel treatment strategies, and alternative therapies are desperately needed. There are now multiple lines of evidence suggesting that changes to the pulmonary vasculature are important to the development and progression of COPD, independent of pulmonary hypertension. Hence, we hypothesize that a vascular-targeted therapy can be a potent and reliable way of monitoring and possibly changing the course of COPD progression. This review focuses on the potency and promise, as well as challenges, of developing vascular-targeted therapy in alleviating the early onset of COPD signs and symptoms.
A country-of-origin analysis of tourist expenditure: the case of Turkey
Authors: Baum Tom , Mudambi Ram
Published: June 2017

While there is large literature on tourist flows and expenditure shares among several destinations, the quantitative analysis of tourist expenditure in a single country is less well-developed. The first objective of this paper is to isolate characteristics which explain the levels of overall tourist expenditure based on the different originating countries. The second objective is to develop a quantitative method of optimizing the use of a government tourism promotional budget using outlier analysis. Using a comprehensive dataset obtained from the Tourism Board of the Government of Turkey, we find that the most consistently significant determinant of expenditure is the percentage of business travellers. The strongest positive outlier appears to be Switzerland, followed by Japan, Spain and Saudi Arabia. This should provide some indication of the most promising target markets for the Turkish Tourist Board.
Databank: The Middle East
Authors: Fletcher John , Latham John
Published: June 2017

Tourism activity and economic performance, particularly in the major tourism generating and receiving countries, are closely linked. The purpose of this section is to provide those indicators which are regarded as most relevant to international movements and spend. In Volume 1, Number 1, information relating to the global and regional pictures of tourism were presented, together with some specific details regarding tourism activity with respect to the most significant nations. Further issues have concentrated on specific world regions. Here, economic indicators relating to tourism in the Middle East are provided.
Customer Satisfaction in Banking Industry: A Gap Analysis Approach
Authors: Kaur Mandeep , Sharma Nitasha , Kapoor Samriti
Published: June 2017

The financial reforms initiated in the year 1991 posed a lot of challenges before the Indian banking sector; one of the major challenges faced by retail banking deals with the customer satisfaction and loyalty. Today’s banking customers have become more aware and rational in their approach than ever. Customer satisfaction and formulation of marketing strategies to attract more and more customers towards the banks are now becoming a key issue in order to survive in the competitive banking industry for every bank. The current study is an attempt to find out the gap between the expected and the perceived satisfaction levels of bank customers. For the purpose of the study, data were collected through primary sources by framing a questionnaire on the basis of SERVQUAL scale and review of literature. To analyse the collected data, Gap Analysis and t-test have been employed. The results of the study bring out the major differences in customers’ expectations and perceptions from banking services, thus showing dissatisfaction among bank customers.
Study on Salespersons’ Task-related Performance Benefits Perceptions and Satisfaction with Sales Force Automation
Authors: Mittal Sanjiv , Gera Rajat , Singhvi S.R.
Published: June 2017

The study empirically extracts the dimensions of perceived sales performance benefits of sales force automation (SFA) tools as perceived by sales professionals in India and empirically tests the antecedent relationship of salespersons’ perceptions with their overall satisfaction with SFA tools. Benefits of SFA tools as perceived by sales professionals were found to be a three-dimensional construct consisting of the factors (dimensions) of ‘selling effectiveness’, ‘cost of selling’ and ‘customer relationships’. All the three factors were found to be significant antecedents of overall satisfaction of sales professionals with SFA tools. The study was conducted with sales professionals of two large companies in India engaged in B2B selling. The study measures empirically determine the effect of sales professionals’ perceptions of benefits of SFA tools with their overall satisfaction and provide partial empirical support for the theoretical framework of cognitive evaluations leading to emotional appraisal, which is an attitudinal construct in the context of SFA tools adoption.
Cloud Computing for Business Sustainability
Authors: Kumar Vikas , Vidhyalakshmi P.
Published: June 2017

Sustainable business approaches help in generating profits by improving business practices, without any negative impact on the global or local environment. Global enterprises always encounter issues, challenges and opportunities to endure in the long run. Most of the organisations use Information and Communication Technology (ICT) tools such as Management Information System (MIS), Decision Support System (DSS), Business Intelligence (BI), Knowledge Management (KM) and web collaboration to achieve the agility in business. This may also drastically increase the energy consumption, causing a big environmental concern. In the process of achieving business agility, sustainability takes a back seat and this can have a long-term impact on the business environment. The optimal and cost-effective solution for this problem can be achieved by Cloud Computing, which gives agility to business and provides a platform for sustainable business with increased profits, better environment and human resource management. Many organisations still have inhibitions in migrating to Cloud due to its high dependency on Internet. In the present work, the role of Cloud Computing paradigm has been discussed to achieve the business agility and sustainability. The effects of Cloud Computing on people, planet and profits, as three important factors of sustainability, have been presented. Industrial case studies have been presented as the Cloud Computing success stories.
Book Review: Research Methodology: Concepts and Cases
Authors: Jacob Wallace
Published: June 2017

Deepak Chawla and Neena Sondhi, Research Methodology: Concepts and Cases, 2011, New Delhi: Vikas Publishing House Pvt. Ltd, pp. xxiv + 670, ₹425, ISBN: 9788125952053.
Does the Dividend Announcement Matter in the Indian Stock Market?
Authors: Kumar Santosh , G. Raju
Published: June 2017

Over the past few years, many firms have announced dividends which give conclusive but indirect signal to the investors. The Dividend is declared to show sufficient profitability to finance future expansion in the firms. Dividend declarations have become an important area in financial research considering its strong implications for corporate policy. The article investigates the signalling effect of the dividend announcements and also the significance of cumulative abnormal return of dividend announcements before and after the event day. Further it also tests the evidence of average abnormal return around the announcement date. The analysis uses data of 42 firms in the BSE 500 index, which have announced dividends during the period 2007–2009. An examination of share price behaviour around dividend announcements proves the signalling effect of these announcements. These results strongly support that the share prices drift positively in the case of dividend announcements and the market particularly reacts more favourably to dividend announcements.
Authentic Leadership: The Role of Self-Awareness in Promoting Coaching Effectiveness
Authors: Gatling Anthony R. , Castelli Patricia A. , Cole Matthew L.
Published: June 2017

Authentic leadership encompasses four dimensions crucial for the success of leadership: self-awareness, relational transparency, balanced processing and internalised moral perspective. In the context of Business Coaching, authentic leadership is a crucial factor in the coach–client relationship in which the leader demonstrates to others a genuine and honest desire to understand their leadership in order to serve others more effectively. The current study investigated the relationship between leadership style and coaching effectiveness among 96 business coaches from the Professional Business Coaches Alliance (PBCA). Study results indicate authentic leadership and its constitutive factor self-awareness were significantly related to coaching effectiveness. Coaching organisations, franchises and alliances, may benefit from this research if they wish to leverage higher levels of authentic leadership and self-awareness when developing selection, assessment, training and measurement systems.
Effect of Social Media Outreach Engagement in Institutions of Higher Learning in India
Authors: Swaminathan T.N. , Harish Amar , Cherian Binoy
Published: June 2017

Word of mouth has for long been the holy grail of marketing. Word of mouth now is word of mouse. Peer reviews, opinions and comments are now the number one influencer prior to choosing an institution of higher learning amongst students considering their relatively high exposure to social media. In this research a study was made on 160 respondents who embraced the online community on social sites like Facebook, Orkut and PaGalGuy as aspirants in five B Schools across India. The participants’ patterns and their level of participation were observed. The survey measured the defined variables to verify the hypotheses on the flow of information and perceptions using a 7-point Likert scale. The conceptualisation of social identity consisted of three dimensions: evaluative social identity, cognitive social identity and affective social identity, each of which contained three items. The study indicated that the prospective students of B Schools participate in social media discussions not necessarily on account of social identity created but on account of behaviour identity of the individual; Information relevance is not as significant as information value; Information value drives usage frequency and Usage frequency is a significant driver for the post participative behaviour. The findings will be useful for the B Schools by tracking the usage, involve those active in the group prior to joining in Brand (School) Building activities at a later phase (as alumni).
Managing Knowledge Transfer—A Communication-appropriation Perspective
Authors: Law Kuok Kei
Published: June 2017

This article presents a communication-appropriation perspective for examining knowledge transfer behaviours of workers. The proposed theoretical perspective is stemmed from the knowledge-as-power phenomenon and the knowledge transfer dilemma of workers, which argue that knowledge transfer may not represent the best option of workers due to the worries of losing knowledge appropriability and organisational power. Based on such psychological tension of workers, the communication-appropriation perspective advocates that workers may manipulate the mode of communication (codification and personalisation) in the knowledge transfer process as a responsive strategy to their appropriation threats so as to result in an incomplete transfer of knowledge. The present work differs from past research in its emphasis on the workers’ perspective of knowledge transfer management which has been relatively under-researched as compared to the organisation’s. The developed theoretical perspective is able to enhance our understanding of the influences of power struggles and appropriation concerns on the knowledge transfer behaviours and strategies of workers.
Supply Chain Management Components, Competitiveness and Organisational Performance: Causal Study of Manufacturing Firms
Authors: Ganeshkumar C. , Nambirajan T.
Published: June 2017

Supply Chain Management (SCM) is a complex subject, which is an important determinant of success or failure of any manufacturing enterprise. It is absolutely essential for executives of manufacturing enterprises to be thoroughly aware about all the essential components of supply chain management and understand the impact that it might exert on the overall efficiency of the organisation. This knowledge will enable them to focus on those variables which add value to organisations and considering the significance of SCM, especially in Indian context, the researcher has made a sincere attempt to find a solution to the research question of ‘What is the impact of important components of SCM on the performance of the supply chain per se and also on the organisational performance in Indian context?’ Based on the review of literature relating to supply chain management components, competitiveness and organisational performance of manufacturing enterprises, a conceptual model was framed and the resulting hypotheses were empirically tested. Data was collected from the executives of these manufacturing enterprises by administering a well structured questionnaire, using personal interview method and tested the proposed research hypotheses. The findings from the structural equation model results support all the 10 formulated hypotheses that there is a significant positive relationship with the supply chain management and organisational performance.
Does Portfolio Mix Influence the Mutual Fund Performance?
Authors: Walia Nidhi , Kumar Ravinder
Published: June 2017

Mutual funds put forward a way out to investors to approach maximum securities and get well-diversified portfolio, as investors with small savings neither have sufficient expertise nor have the means for diversification. Fund managers have responsibility to satisfy investors by offering them maximum return at calculated risk. In the anticipation of earning maximum return on investment, fund managers start working on the philosophy of ‘higher the risk, higher the return’ and accordingly focus mainly on equity stock in the portfolio. Whereas in reality the portfolio returns are influenced by many other funds that include market conditions, timings of investment and investment skills of managers. The results highlighted in this article are based on study of absolute returns and risk measures of four mutual funds studied for a period of 36 months. The findings of our analysis provide that fund managers cannot maximise their RoI by investing heavily in the risky securities. Instead the fund managers’ abilities to select quality stock and the appropriate timing determine the risk return trade-off attached with the funds. The article presents the investment styles of various fund managers that they apply to design varied portfolio mix by picking up different securities and the results highlighted provide that fund managers’ superior strategies to select stock alongwith the fund composition enhances the returns and reduces the impact of market volatility.
Benchmarking Sustainability: Study of Initiatives towards Triple Bottom Line by Indian Public Sector Enterprises
Authors: Oberoi Roopinder
Published: June 2017

The triple bottom line (TBL) has become one of the main rallying cries for businesses trying to address sustainability. There is a paradigm shift happening with corporate responsibility and sustainable development (SD) by the corporates slipping away from ‘zone of voluntariness’ and ‘getting gripped by debate on accountability and benchmarking’. The new environmental and social standards developed locally and globally have turned sustainability into a ‘cost of entry’ for businesses. Implementing sustainability in a top-down fashion leads to a central focus on government in managing and regulating for corporate sustainability. Reich ( 1998 ) argues that the government should act as arbiter of business responsibility in society. Governments that lead as exemplar will be in a stronger position to set the agenda and establish advanced positions for their industries and their citizens. This article focuses on the role of governments in endorsing corporate sustainability, while making a note of the impact of promoting sustainability in the Indian central public sector. It asks very straight questions—How far is it working in practice? Are their tangible changes happening with corporates leading towards TBL? Are corporate serious of developing sustainability metrics and appreciating the need for standardised approaches?

The article in the first section explores some of the conceptual issues in the TBL to deal with sustainability. Then, it looks at the recently promulgated Sustainable Development Guidelines for Central Public Sector Enterprises in India (2013) and the ways in which these actions can be tracked to demonstrate and reveal the contribution and commitment of the business entities in shaping a sustainable growth path for the nation. The case of two prominent central public sector enterprises (CPSEs) was undertaken to study their coverage and application towards the implementation of government guidelines on sustainable development (SD). Both these companies fall under the categorisation of extractive industries. The extractive industries face a special need for such trust, given the massive long-term investments that they undertake in countries. The study indicates that these two companies have engaged in serious efforts to embed sustainability in their corporate strategy and are equally transparent in their reporting patterns. Their reports on triple bottom line parameters are comprehensive and externally assured. The institutionalisation of sustainability benchmarking within the DNA of government enterprises will go a long way in mandating sustainability practices for other businesses. Data for the article was collected through secondary sources, via government websites, policy document by Ministry of Corporate Affairs, corporate websites, newspapers and scholarly papers. From these sources, specific examples of achieved outcomes were identified and considered.
Quasi-Monte Carlo Approach to Asian Options Pricing
Authors: Kubendran N. , Rachiraju Laxmi Sowmya , Mishra Aswini Kumar , Bommareddy Aruna
Published: June 2017

Asian options is a contract which gives right to the holder to buy/sell the underlying asset for its average price over prescribed period and it has a lower unpredictability, hence exposing cheaper relative to their European counterparts. Asian options are commonly traded on currencies and commodity products which have low trade volumes. Therefore, the pricing of such options become one of the most interesting fields. Much research work has been done on the European and American options using various techniques like Black-Scholes, binomial tree, finite difference, Monte Carlo and Quasi-Monte Carlo model. But none of the studies compares and identified the best model for options pricing, particularly for Asian options pricing. This article aims to evaluate the effectiveness of existing models on Asian options pricing and to suggest a suitable model for forecasting Asian options prices. Findings of the study indicate that the Quasi-Monte Carlo technique is more superior to any other techniques due to its results with high precision and low standard deviation.
Green Marketing: Development of Construct and Its Evolution
Authors: Laheri Vishal Kumar , Dangi Hamendra , Vohra Anupama
Published: June 2017

Marketing as a discipline has evolved over a period of time where the traditional concept imparts that goods were produced to be sold to the customers and the modern marketing states that goods are produced according to the needs and demand of the customers. The current marketing management emphasises on satisfying the needs of the customers without any environmental degradation. This green concept is building over the last decade because of consumer concern, government regulations, environmental lobbies’ pressure and social responsibilities of the corporates towards environment. Also green marketing is offering a new competitive advantage to the companies who wish to target their green consumers. The current study aims to sketch out the concept of green marketing by discussing and analysing the existing knowledge of the definitions, themes, dimensions and their components so as to frame chronologically development of the same.
Heteroscedasticity in Diffusion of Promotional Strategies Adopted by Companies: The Consumer Review Analysis
Authors: Grover Saurabh , Hundal B.S.
Published: June 2017

The present study focuses on consumer behaviour towards cars. The rural consumer is in a buoyant mood and has an optimistic outlook. This is a positive sign and an indicator for the car industry, but nothing is available in a platter and tapping the rural market is real hard work but nevertheless, the future no doubt, lies in the rural markets, since the size of rural market in quantitative and qualitative terms, is growing at a great pace. In case of rural consumers, it is somewhat difficult to understand their views while making choices among different products. Perception towards promotional strategies among car buyers has been studied and data of both urban and rural buyers is taken to fulfil the present objective. Factor analysis and discriminant analysis have been applied on the data of 477 respondents from urban and rural Punjab (India). It is recommended that marketer have to provide monetary incentives to rural people in order to attract them but these promotional techniques play negligible role in urban areas.
A Comparative Study of Perceived Satisfaction of Employees Regarding Performance Management System in Context of IT Organisations
Authors: Mishra Geeta
Published: June 2017

Performance Management System (PMS) has always been a key concern in HR process and has attracted significant attention from both academicians and practitioners. The study was conducted in IT organisations in India as the growth in the service sector in India has been led by the IT–ITES sector, contributing substantially to increase in GDP, employment and exports. The study aims at comparing the perceived satisfaction of employees across IT organisations and exploring the mechanism of PMS in the selected organisations under study. Findings of the study present interesting and significant insights into the mechanism of PMS in IT organisations and in understanding the differences in perceived satisfaction of employees across organisations.
Editorial: The secrets of secretion
Authors: Catz Sergio D
Published: June 2017

Discussion on neutrophil exocytosis and priming.
Waveform-based source location method using a source parameter isolation strategy
Authors: Huang Chao , Dong Liang-Guo , Liu Yu-Zhu , Yang Ji-Zhong
Published: June 2017

We have developed a novel acoustic-wave-equation-based full-waveform source location method to locate microseismic events. With the acoustic-wave equation and source signature independent inversion strategy, source location parameters (hypocenter locations) can be isolated from others and can then be retrieved independently and accurately, even when the origin time and source signature are not correct. Based on the acoustic-wave equation, new Fréchet derivatives of seismic waveforms with respect to the location parameters are derived to better accelerate the inversion process. To ease the cycle-skipping problem, a correlation is applied to select the best starting source positions. Some 2D and 3D numerical examples are presented to demonstrate the validity of our method. Compared with the waveform-based grid-search method, our method is effective in isolating the hypocenter locations from the source signature and origin time. The computational cost is nearly negligible compared with the waveform-based grid-search method. The robustness of our method is also tested for cases with inaccurate velocity models or using microseismic data with a signal-to-noise ratio of ≥[Formula: see text]. Finally, field data are used to indicate the practical applicability of our method.
Cautious Citizenship: The Deterring Effect of Immigration Issue Salience on Health Care Use and Bureaucratic Interactions among Latino US Citizens
Authors: Pedraza Franciso I. , Nichols Vanessa Cruz , LeBrón Alana M. W.
Published: June 2017

Research shows that health care use among Latino immigrants is adversely affected by restrictive immigration policy. A core concern is that immigrants shy away from sharing personal information in response to policies that expand bureaucratic monitoring of citizenship status across service-providing organizations. This investigation addresses the concern that immigration politics also negatively influences health care utilization among Latino US citizens. One implication is that health insurance expansions may not reduce health care inequities among Latinos due to concern about exposure to immigration law enforcement authorities. Using data from the 2015 Latino National Health and Immigration Survey, we examine the extent to which the politics of immigration deters individuals from going to health care providers and service-providing institutions. Results indicate that Latino US citizens are less likely to make an appointment to see a health care provider when the issue of immigration is mentioned. Additionally, Latino US citizens who know someone who has been deported are more inclined to perceive that information shared with health care providers is not secure. We discuss how cautious citizenship, or risk-avoidance behaviors toward public institutions in order to avoid scrutiny of citizenship status, informs debates about reducing health care inequities.
Re-examining the role of Cdc14 phosphatase in reversal of Cdk phosphorylation during mitotic exit
Authors: Powers Brendan L. , Hall Mark C.
Published: June 2017

Inactivation of cyclin-dependent kinase (Cdk) and reversal of Cdk phosphorylation are universally required for mitotic exit. In budding yeast (Saccharomyces cerevisiae), Cdc14 is essential for both and thought to be the major Cdk-counteracting phosphatase. However, Cdc14 is not required for mitotic exit in many eukaryotes, despite highly conserved biochemical properties. The question of how similar enzymes could have such disparate influences on mitotic exit prompted us to re-examine the contribution of budding yeast Cdc14. By using an auxin-inducible degron, we show that severe Cdc14 depletion has no effect on the kinetics of mitotic exit and bulk Cdk substrate dephosphorylation, but causes a cell separation defect and is ultimately lethal. Phosphoproteomic analysis revealed that Cdc14 is highly selective for distinct Cdk sites in vivo and does not catalyze widespread Cdk substrate dephosphorylation. We conclude that additional phosphatases likely contribute substantially to Cdk substrate dephosphorylation and coordination of mitotic exit in budding yeast, similar to in other eukaryotes, and the critical mitotic exit functions of Cdc14 require trace amounts of enzyme. We propose that Cdc14 plays very specific, and often different, roles in counteracting Cdk phosphorylation in all species.
Direito à saúde: medicamentos mais solicitados por demandas administrativas e judiciais por uma secretaria estadual de saúde no biênio de 2013 a 2014
Authors: Botelho Pauline de Ataíde , Pessoa Nívia Tavares , Lima Alisson Menezes Araujo
Published: June 2017

Introdução: O uso da via judicial para o fornecimento de medicamentos presentes nas listas oficiais públicas é uma forma legítima de garantir o pleno exercício do direito à assistência individual terapêutica, que integra o direito à saúde na lei brasileira. Objetivo: Descrever o perfil dos processos administrativos e judiciais de solicitação de medicamentos à Secretaria de Saúde do Estado do Ceará, analisando a origem dessa demanda, os 10 princípios ativos mais solicitados em cada ano e suas principais indicações terapêuticas. Métodos: Estudo documental descritivo e retrospectivo de abordagem quantitativa. Foram analisadas as solicitações via processo administrativo e judicial ingressadas na Secretaria de Saúde do Estado do Ceará de janeiro de 2013 a dezembro de 2014. Nesse estudo as variáveis utilizadas foram adaptadas do Manual de Indicadores de Avaliação e Monitoramento das Ações Judiciais de Medicamentos. Para a análise dos dados, utilizou-se o SPSS® versão 15.0. A análise foi descritiva utilizando freqüência simples, média e porcentagem. Resultados: A Secretaria de Saúde do Estado do Ceará, através do CEIMED (Centro de Estudos e Informações Sobre Medicamentos) recebeu em 2013 um total de 1156 processos no total com um aumento de 33,91% no ano de 2014, totalizando 1548 processos. Os princípios ativos mais relevantes de 2013 foram: rituximabe (câncer) e teriparatida (osteoporose); em 2014 rituximabe (câncer) e insulinas (diabetes). Conclusão: O crescente processo de judicialização da saúde tem implicado grandes desafios às esferas municipal, estadual e federal por impactar diretamente nos orçamentos. Nota-se que a assistência ao paciente com medicamentos já padronizados ainda necessita de eficácia prática, seja em não faltar nos locais de dispensação, seja em não gerar demanda processual desnecessária. O tratamento para diversos tipos de câncer, osteoporose e diabetes insulino-dependente necessitam de atenção especial quanto ao custo-beneficio imposto ao tratamento desses pacientes.
Atenção farmacêutica e os potenciais riscos da polifarmácia em idosos usuários de uma farmácia-escola de Minas Gerais: aspectos socioeconômicos, clínico e terapêutico
Authors: Da Silva Patrick Leonardo Nogueira , Xavier Arley Gomes , De Souza Denival Alves , Vaz Maria Dolores Tiago
Published: June 2017

Objetivo: investigar a atenção farmacêutica dos potenciais riscos da polifarmácia em idosos usuários de uma farmácia-escola de Minas Gerais quanto aos aspectos socioeconômicos, clínicos e terapêuticos. Método: trata-se de um estudo descritivo, exploratório, retrospectivo, com abordagem quantitativa, realizado com 30 idosos usuários de uma Farmácia-Escola. Utilizou-se uma entrevista semiestruturada como instrumento de coleta de dados, os quais foram analisados por meio de epidemiologia descritiva simples, não probabilística. Resultados: predominou o gênero feminino, com idade entre 60-70 anos, ensino fundamental completo cujas pessoas utilizavam corretamente o medicamento, não se esqueciam de utilizá-lo, não conheciam sobre a terapia não farmacológica e os riscos da polifarmácia, não tinham acompanhamento de profissional de saúde habilitado. A Losartana 50mg apresentou maior prevalência de uso, com bom índice de aceitabilidade, quando comparada aos demais fármacos relatados. Constatou-se que a hipertensão arterial sistêmica prevaleceu entre as patologias relatadas pelos idosos. Conclusão: o uso da polifarmácia é predominante em mulheres idosas, de baixo nível socioeconômico, predispostas ao surgimento e complicações de doenças crônicas não transmissíveis, com prevalência da hipertensão arterial sistêmica, em decorrência da falta de conhecimento quanto à terapia não farmacológica e dependência medicamentosa.
ОРГАНИЗАЦИЯ ИНТЕРАКТИВНОГО ОБУЧЕНИЯ С ПОМОЩЬЮ MS EXCEL В КАЧЕСТВЕ ИНСТРУМЕНТА КОМПЬЮТЕРНОЙ СИМУЛЯЦИИ
Authors: Manyukova Natalya Vladislavovna , Nikonova Elena Zakharovna
Published: June 2017

Цель. Статья посвящена актуальным в условиях ФГОС ВО 3-го поколения требованиям использования интерактивных форм обучения. Предметом анализа являются способы активизации познавательной деятельности обучающихся. Авторы ставят перед собой цель подбора оптимальных форм и средств организации учебного процесса в вузе.Метод или методология проведения работы. Основу исследования образуют анализ литературы, моделирование, наблюдение и эксперимент.Результаты. Результаты работы заключаются в том, что авторы выявляют особенности и компоненты метода компьютерной симуляции. На основе анализа практического применения данного метода были сформулированы необходимые этапы его реализации на учебном занятии. В качестве одного из инструментов реализации метода компьютерной симуляции авторы рассматривают программу MS Excel. В статье приводятся конкретные примеры применения электронных таблиц для компьютерного моделирования.Область применения результатов. Результаты исследования могут быть использованы в преподавании различных дисциплин.
PROPERTIES OF Ni-Ti-X SHAPE MEMORY ALLOYS PRODUCED BY ARC RE-MELTING
Authors: Salvetr Pavel , Školáková Andrea , Kopeček Jaromír , Novák Pavel
Published: June 2017

This paper deals with Ni-Ti46 and Ni-Ti-X wt. % alloys prepared by arc re-melting under argon protective atmosphere. The melting was repeated three times to obtain a homogenous chemical composition of samples. Niobium, vanadium and silicon were chosen as alloying elements and they were added into the alloy in an amount of 5 wt. %. Microstructure, phase composition, hardness and transformation behaviour were investigated parameters. Properties of cast alloys are compared with alloys of the same chemical composition prepared by powder metallurgy method – self-propagating high-temperature synthesis (SHS). Arc re-melting produced a more homogeneous microstructure with a lower content of the Ti2Ni phase than powder metallurgy methods in case of Ni-Ti-X alloys. Quite a high amount of the secondary phase (a mixture of the Ni2Ti, NiTi and Ti2Ni phases) was created in the microstructure of Ni-Ti46 wt. % alloy. The addition of silicon caused an increase of transformation temperatures and hardness.
MECHANICAL, CORROSION AND WEAR BEHAVIOUR OF STEEL CHIPS AND GRAPHITE REINFORCED Zn-27Al ALLOY BASED COMPOSITES
Authors: Alaneme Kenneth Kanayo , Ajibuwa Oluwadamilola Abigail , Kolawole Ifedolapo Elizabeth , Fajemisin Adetomilola Victoria
Published: June 2017

The prospect of enhancing mechanical, corrosion and wear properties of Zn27Al alloy based composites reinforced with steel machining chips by graphite addition was the focus of this investigation. Double stir casting was used to produce Zn27Al alloy based composites with 7 wt.% reinforcement but with varied compositions containing 1, 2, and 3 wt.% graphite, steel chips making up the balance. Microstructural analysis, mechanical, corrosion and wear tests were used to characterise the composites. The results show that the hardness of the composites decreases slightly with an increase in graphite content in the reinforced composites. The tensile strength and fracture toughness of the composite only showed improvement with the addition of 3 wt.% graphite in the hybrid mix (steel chips and graphite) compared with the use of lower graphite content in the mix and steel chips only. The percent elongation did not show dependency on the composition of the reinforcement phase and was basically within the range 6.0 - 6.8 %. The fracture surfaces of all the composites were essentially rough, a preponderant feature of ductile fracture mode. The wear index of the composites was generally low indicating good wear resistance. However, despite the seeming self-lubricating advantage of graphite, the wear resistance of the composite reinforced with only steel chips was relatively better than that of the hybrid graphite, and steel chips reinforced composite compositions. Finally, the steel chips and graphite reinforced Zn-27Al alloy based composites were generally more corrosion resistant in 3.5% NaCl solution compared with the unreinforced Zn-27Al alloy.