bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk factors and the occurrence of cerebral palsy in high risk infants
Authors: Handryastuti Setyo , Ismael Sofyan , Sastroasmoro Sudigdo , Aminulah Asril , Idris Ferial Hadipoetro , Saptogino Adji , Hapsara Sunartini
Published: May 2018

Background The incidence of cerebral palsy (CP) has increased due to better survival rates of high-risk babies. Early detection and time to the occurrence of CP in the first year of life is important in order to provide early intervention.Objectives To determine the proportion of CP in high-risk babies, the time to the occurrence of CP in the first year, and assess possible associations between risk factors of CP and time to the occurrence of CP.Methods A prospective cohort study was done on 150 high-risk babies up to the age of 12 months. We obtained history of motor ability and assessed primitive reflexes and postural reactions of subjects at the ages of 4 and 6 months. The diagnosis of CP was established at 6 and 12 months of age.Results The proportion of CP was 26% at 6 months and 24% at 12 months of age. Significant risk factors associated with CP at 6 and 12 months of age were cerebral ultrasound abnormalities, hypoxic-ischemic encephalopathy, and intracranial hemorrhage. In 88.7% of subjects with CP, CP was detected in the first 6 months. Mean age at the occurrence of CP was 9.99 months (95%CI 9.46 to 10.53). Risk factors that significantly affected the time to the occurrence of CP by survival analysis were ultrasound abnormalities and hypoxic-ischemic encephalopathy.Conclusions Cerebral palsy can be detected as early as the first 6 months of life. Cerebral ultrasound abnormalities and hypoxic ischemic encephalopathy are the risk factors associated with CP.
A revision of Sagriva (Hemiptera: Heteroptera: Dinidoridae)
Authors: Rédei Dávid
Published: May 2018

The Indomalayan genus Sagriva Spinola, 1850 (Hemiptera: Heteroptera: Dinidoridae: Dinidorinae) is revised. The identity of its single previously valid species, S. vittata Spinola, 1850, is clarified based on the relevant type material, the species is diagnosed, illustrated, and recorded for the first time from Thailand and Laos. A new species, Sagriva banna sp. nov., is described from Yunnan Province of China and Yen Bai Province of Vietnam.
Periscelis fugax sp. nov., an overlooked European species of Periscelididae (Diptera), with notes on the morphology and terminology of terminalia
Authors: Roháček Jindřich , Andrade Rui
Published: May 2018

Periscelis (Periscelis) fugax sp. nov. is described and illustrated based on series of specimens from Portugal and the Czech Republic. It is probably widespread in Europe but has not been previously recognized from the closely related and externally very similar P. (P.) winnertzii Egger, 1862. The new species differs from P. winnertzii not only in structures of the male and female terminalia (illustrated) but also in colour pattern of pedicel and mesonotum. Morphology of the male and female terminalia is studied in detail in both these species and terminology of their structures is discussed and redefined. A new modern key to Palaearctic species of Periscelis (s. str.) species is constructed.
Tinea altaica sp. nov. and new records of some small moths from the Russian Altai (Lepidoptera: Meessiidae, Tineidae, Douglasiidae, Epermeniidae, Glyphipterigidae: Acrolepiinae)
Authors: Gaedike Reinhard , Šumpich Jan
Published: May 2018

The paper summarizes the results of our study of selected Microlepidoptera families (Meessiidae, Tineidae, Douglasiidae, Epermeniidae, Glyphipterigidae: Acrolepiinae) collected in the Russian Altai. Tinea altaica sp. nov. is described from the vicinity of Tashanta on the Russian-Mongolian border and from Mongolia. The new species distantly resembles Tinea semifulvella Haworth, 1828 and T. semifulvelloides Petersen, 1973. The up to now unknown females of Klimeschia biarmatella Budashkin, 2003 and Monopis luteocostalis Gaedike, 2006 are described. Scardia boletella (Fabricius, 1794), Crassicornella crassicornella (Zeller, 1847), Trichophaga ziniella Zagulajev, 1960, Tineola bisselliella (Hummel, 1823), Monopis laevigella (Denis & Schiffermüller, 1775), M. pallidella Zagulajev, 1955, Epermenia ochreomaculella asiatica Gaedike, 1979, and Acrolepiopsis sapporensis (Matsumura, 1931) are recorded from the Altai Republic for the first time. Tinea hongorella Zagulajev, 1975 and Klimeschia biarmatella Budashkin, 2003, so far known only from the holotypes, are new species for Russia. Tinea hongorella is also a new species for Europe.
Histeridae of Socotra (Coleoptera: Histeroidea)
Authors: Lackner Tomáš , Vienna Pierpaolo
Published: May 2018

The histerid beetles (Coleoptera: Histeridae) of Socotra Island (Yemen) are reviewed based on the material collected during the Czech expeditions undertaken between 2000 and 2012. A total of 20 species are recorded, three of which are described herein: Pachycraerus socotrensis sp. nov., Liopygus occidentalis sp. nov., and Teretrius (Neoteretrius) dispar sp. nov. Hypocaccus virescens Thérond, 1963 is transferred from the subgenus Baeckmanniolus Reichardt, 1926 to Hypocaccus s. str. Thomson, 1867 based on external morphology. Most taxa, albeit determined only up to their (sub)generic rank, are recorded from Socotra for the first time. Due to poor understanding of their taxonomy, or lack of determination keys to the following (sub)genera: Tribalus Erichson, 1834, Plegaderus (Plegaderus) Erichson, 1834, Acritus (Acritus) LeConte, 1853, and Teretrius (Teretrius) Erichson, 1834, their representatives from Socotra are left without identification pending revisions. The Socotran histerid fauna has been found to consist mainly of widely distributed African, Arabian/Near Eastern taxa, as well as local endemics. The occurrence of the (predominantly Holarctic) genus Plegaderus and the exclusively southeast Asian genus Liopygus Lewis, 1891 in Socotra is highly interesting.
Used Furan Sand Reclamation in REGMAS Vibratory Unit
Authors: Dańko J. , Dańko R. , Skrzyński M.
Published: May 2018

The paper, especially dealt with problems of reclamation of used furan sand, carried out in new, vibratory sand reclamation unit REGMAS developed by researches from AGH-University of Science and Technology, Faculty of Foundry Engineering in Cracow (Poland). Functional characteristics of reclamation unit as well as the results of reclamation of used sand with furfuryl resin are discussed in the paper. The quality of reclaim was tested by means of the LOI and pH value, dust content in the reclaim and at least by the the quality of the castings produced in moulds prepared with the use of reclaimed matrix.
Properties of AlSi9Mg Alloy Matrix Composite Reinforced with Short Carbon Fibre after Remelting
Authors: Łągiewka M. , Konopka Z.
Published: May 2018

The presented work describes the results of examination of the mechanical properties of castings made either of AlSi9Mg alloy matrix composite reinforced with short carbon fibre or of the pure AlSi9Mg alloy. The tensile strength, the yield strength, Young’s modulus, and the unit elongation were examined both for initial castings and for castings made of the remelted composite or AlSi9Mg alloy. After preparing metallographic specimens, the structure of the remelted materials was assessed. A few non-metallic inclusions were observed in the structure of the remelted composite, not occurring in the initial castings. Mechanical testing revealed that all the examined properties of the initial composite material exceed those of the non-reinforced matrix. A decrease in mechanical properties was stated both for the metal matrix and for the composite after the remelting process, but this decrease was so slight that it either does not preclude them from further use or does not restrict the range of their application.
A Survey on Differential Geometry of Riemannian Maps Between
Authors: Şahin Bayram
Published: May 2018

The main aim of this paper is to state recent results in Riemannian geometry obtained by the existence of a Riemannian map between Riemannian manifolds and to introduce certain geometric objects along such maps which allow one to use the techniques of submanifolds or Riemannian submersions for Riemannian maps. The paper also contains several open problems related to the research area.
Generalized Sasaki Metrics on Tangent Bundles
Authors: Vaisman Izu
Published: May 2018

We define a class of metrics that extend the Sasaki metric of the tangent manifold of a Riemannian manifold. The new metrics are obtained by the transfer of the generalized (pseudo-)Riemannian metrics of the pullback bundle π−1(TM⊕T*M), where π : T M → M is the natural projection. We obtain the expression of the transferred metric and define a canonical metric connection with torsion. We calculate the torsion, curvature and Ricci curvature of this connection and give a few applications of the results. We also discuss the transfer of generalized complex and generalized Kähler structures from the pullback bundle to the tangent manifold.
Approximation Properties of Bivariate Generalization of Meyer-König And Zeller Type Operators
Authors: İnce H. Gül , Özkan Esma Yildiz
Published: May 2018

In this paper, a bivariate generalization of a general sequence of Meyer-König and Zeller (MKZ) operators based on q-integers is constructed. Approximation properties of these operators are obtained by using either Korovkin-type statistical approximation theorem or Heping-type convergence theorem for bivariate functions. Rates of statistical convergence by means of modulus of continuity and the elements of Lipschitz class functionals are also established.
On Some Sufficient Conditions for L1-Convergence of Double Sine Series
Authors: Krasniqi Xhevat Z.
Published: May 2018

In this paper we introduce some numerical classes of double sequences. Such classes are used to show some sufficient conditions for L1 −convergence of double sine series. This study partially extends very recent results of Leindler, and particularly those of Zhou, from single to two-dimensional sine series.
ABPP Motion Simulator Based on 3D ENC
Authors: Naus Krzysztof , Zwolan Piotr
Published: May 2018

A research focused on development of numerical model of a sea area destined for a motion simulator of an Autonomous Biomimetic Underwater Vehicle (ABPP) is presented in the paper. There are purpose, construction and functionality of the ABPP motion simulator generally characterized in the introduction. The first part contains description of a method of creating the sea area model based on the data included in the Electronic Navigational Chart (ENC). A method of displaying the sea area model in the ABPP motion simulator, with a use of the Open GL graphic library, is described in the second part. Finally, there are conclusions drawn from the executed research given at the end.
Current State of Deep Ocean Bathymetric Exploration
Authors: Zwolak Karolina , Felski Andrzej
Published: May 2018

The paper presents current state of bathymetric survey concerning deep ocean rather than shallow areas, which are better surveyed due to safety of navigation concerns. Rules and requirements of the new challenge, called the Shell Ocean Discovery XPRIZE, became a starting point for a discussion about the possibilities of mapping large areas of the ocean using up-to-date and new technology. The amount of bathymetric data available nowadays and the current state of ocean map compilations are also discussed in the paper as a motivation to inspire the new initiatives in the deep ocean.
Experimental investigation of single-phase microjet cooling of microelectronics
Authors: Rusowicz Artur , Leszczyński Maciej , Grzebielec Andrzej , Laskowski Rafał
Published: May 2018

Development of electronics, which aims to improve the functionality of electronic devices, aims at increasing the packing of transistors in a chip and boosting clock speed (the number of elementary operations per second). While pursuing this objective, one encounters the growing problem of thermal nature. Each switching of the logic state at the elementary level of an integrated circuit is associated with the generation of heat. Due to a large number of transistors and high clock speeds, higher heat flux is emitted by the microprocessor to a level where the component needs to be intensively cooled, or otherwise it will become overheated. This paper presents the cooling of microelectronic components using microjets.
Comparison Of Energy Sources Grown On Agricultural Land
Authors: Jureková Zuzana , Húska Dušan , Kotrla Marián , Prčík Martin , Hauptvogl Martin
Published: May 2018

The aim of the paper is to compare biomass production of energy plants and selected crops grown on arable land in the south-western Slovakia in 2007–2014, its energy value and the influence of decisive climatic factors on the size of the production. The data on yields of dominant crops grown in the agricultural farm were obtained from the statistical data of the farm. Aboveground biomass of willows and poplars was harvested at the end of the harvest cycle. Aboveground biomass of Miscanthus sinensis was harvested in 2010–2014, always in early spring period of the following year. Winter wheat, spring barley and maize grown for silage during the period 2007–2014 provided the lowest yields in 2010 and the highest in 2011 and 2014. The highest energy value was obtained from maize in 2014 (400.66 GJ ha−1). The short rotation coppice poplars of Italian provenance yielded biomass with energy value of 951.68 GJ ha−1 year−1 at the end of the first three-year harvest cycle in 2012. The analysis of variance confirmed that there are highly significant statistical differences in the poplar biomass yield among the varieties and individual experimental years. The fast growing willows of Swedish provenance provided aboveground biomass energy value of 868.88 GJ ha−1 year−1 at the end of the first four-year harvest cycle in 2011. The biomass production of the perennial grass Miscanthus sinensis, depending on the growing period, can be expressed by a polynomial trend function. The highest biomass production was obtained in the third growing period (2012). At the end of the fifth growing period (2014), the yield amounted to 28.60 t ha−1 of the dry aboveground biomass. The energy value of the aboveground biomass of Miscanthus reached 486.20 GJ ha−1 in 2014. Differences in the biomass yield of the Miscanthus genotypes are statistically highly significant in each of the monitored growing periods. The growth and production process of the selected energy species reflect the specificities of soil and climatic conditions of the individual growing periods, as well as the ability of individual species and varieties to provide biomass production in the given conditions. Regression analysis of the produced aboveground biomass of the crops grown in the Kolíňany cadastre has not confirmed a statistical dependence in selected climatic parameterss.
Electrocutions – Therapeutic Management - Results
Authors: Ivanov B. , Iordache I.V. , Bratu I.C. , Bordeianu I. , Caraban B.M.
Published: May 2018

The authors present a retrospective study over a period of 18 years on electrocutions that were included electrocutions through direct contact (as the clinical presentation) or that were produced by high voltage or low voltage, which aims at extracting conclusions prognostic and therapeutic nature and especially the final therapeutic results, the study concluded that even electrocutions is decreases incidence, mortality of electrocutions with high voltage remains strong.
Welfare Implication of Paddy Price Support Withdrawal from Malaysian Rice Sector: Partial Equilibrium Method Approach
Authors: Umar Haruna Suleiman , Abdullah Amin Mahir , Shamsudin Mad Nasir , Mohamed Zainal Abidin
Published: May 2018

The study was designed to analyze societal welfare implication of paddy price support withdrawal, as an alternative policy, from rice sector in Malaysia. Time series data (1980-2012) were collected and analyzed through different stages of analyses. The first stage of analysis involved time series econometric model namely, Auto Regressive Distributed Lag (ARDL), which was used in coefficients estimation. Estimated coefficients were subjected to, and passed the relevant diagnostic tests. The estimated elasticities were then used for the second stage of analysis- scenario simulation. Finally, the generated simulation results were further used in estimating the societal welfare changed through appropriate estimation technique. Results show producer welfare loss of about RM189 million, and RM198 million was saved as revenue. The net gain or societal welfare improvement was about RM9 million. Simulated results show up to 10% reduction in paddy producer price or farm income; this could serve as disincentive to rice producers. Since the country is concerned about achieving rice self-sufficiency and rice food security, necessary precautionary measures have to be instituted to prevent farmers exit from paddy farming, by putting a concerted effort towards channeling the trickle-down benefit of societal welfare improvement, resulting from policy option, to rice producers particularly the dominant smallholder group.
Shoot Induction from Axillary Bud of β-Carotene Enriched Manihot esculenta Crantz and Molecular Stability of Regenerants
Authors: Opabode Jelili Titilola , Ajibola Olufemi Victor , Akinyemiju Oluyemisi Amos
Published: May 2018

Inadequacy of planting materials is limiting the distribution of three high-β-carotene (pro-vitamin A) cassava varieties released in Nigeria to increase public vitamin A intake. However, studies have established the suitability of in vitro shoot culture for mass propagation of elite crop varieties for quick distribution to farmers. We investigated multiple shoot induction from axillary bud of three β-carotene enriched cassava varieties using BAP and assessed the genetic stability of the regenerated plants to establish mass propagation system. Multiple shoots were induced from BAP-enlarged axillary bud on basal medium supplemented with 10 mg/l BAP. Shootbuds were elongated on basal medium supplemented with 1.0 mg/l BAP and 10.0 IBA mg/l. Genetic stability of regenerated plants was assessed byeight RAPD markers. There were significant (P < 0.05) differences in survival of isolated axillary bud, shootbud formation, survival of shootbud, regenerated shoots, root formation and survived regenerated plants among cassava varieties. The order of shootbud formation among the cassava varieties was UMUCASS 37 > UMUCASS 36 >TMS 30555 > UMUCASS 38. The best (83.4%) shoot regeneration was recorded in TMS 30572 and lowest (47.8%) in UMUCASS 37, however, UMUCASS 36 recorded the best (98.5%) survival of regenerated shoot after hardening. Eight RAPD primers produced 56 bands, ranging from 200 to 3000 bp in size. RAPD analysis showed a uniform profile among regenerants and between mother plant and regenerants. The study concluded that multiple shoot formation could be induced in pro-vitamin A cassava varieties using BAP from axillary bud with no genetic infidelity of the regenerants.
Analysis of Vapour Liquid Equilibria in Unconventional Rich Liquid Gas Condensate Reservoirs
Authors: Kuczyński Szymon
Published: May 2018

At the beginning of 21st century, natural gas from conventional and unconventional reservoirs has become important fossil energy resource and its role as energy fuel has increased. The exploration of unconventional gas reservoirs has been discussed recently in many conferences and journals. The paper presents considerations which will be used to build the thermodynamic model that will describe the phenomenon of vapour - liquid equilibrium (VLE) in the retrograde condensation in rocks of ultra-low permeability and in the nanopores. The research will be limited to "tight gas" reservoirs (TGR) and "shale gas" reservoirs (SGR). Constructed models will take into account the phenomenon of capillary condensation and adsorption. These studies will be the base for modifications of existing compositional simulators
Experimental Study of Vibrations in Face Milling Cutting
Authors: Oniţă Gabriel Vasile
Published: May 2018

The present paper consists in a comparison of vibrations measured during face milling cutting with two constructive variants of milling cutters (one with classic insert clamping and other with a quick insert adjustment mechanism). The goal of the study is to determine if the new clamping mechanism of the inserts has a similar behaviour with the classic one and can withstand milling conditions without introducing additional vibrations in the system
Distributive and Dual Distributive Elements in Hyperlattices
Authors: Ameri Reza , Amiri-Bideshki M. , Hoskova-Mayerova Sarka , Saeid A. B.
Published: May 2018

In this paper we introduce and study distributive elements, dual distributive elements in hyperlattices, and prove that these elements forms ∧-semi lattice and ∨-semi hyperlattice, respectively. We use the properties of prime ideals and prime filters in hyperlattices. We will proceed to introduce the notion of dual distributive hyperlattices, I-filters and filters generated by dual distributive elements. Finally, the relationship between good homomorphisms and istributive (resp. dual distributive)elements in hyperlattices are investigated.
Para-mixed linear spaces
Authors: Crasmareanu Mircea
Published: May 2018

We consider the paracomplex version of the notion of mixed linear spaces introduced by M. Jurchescu in [4] by replacing the complex unit i with the paracomplex unit j, j2 = 1. The linear algebra of these spaces is studied with a special view towards their morphisms.
Synanthropization of dendroflora near main roads in Białystok (NE Poland)
Authors: Łaska Grażyna
Published: May 2018

The aim of the study was to analyze the species composition of the dendroflora near four main roads in the city of Białystok, taking into regard their geographical and historical origin. The wildlife inventory was conducted in the vegetation season of 2011. The inventory revealed presence of a total of 837 trees and bushes representing 36 species and 18 families. The most abundant trees were those from the family Aceraceae (63.8%), while the most abundant bushes were those representing Rosaceae (48.9%). The contribution of native species (65.7%) was found to be about twice as high as that of alien ones (34.3%). The dominant species among the native trees was Acer platanoides L., while the principal bush species was Crataegus monogyna Jacq. The alien tree species were most commonly represented by Acer negundo L., and bushes - by Ligustrum vulgare L. Spontaneously settled trees and bushes were clearly dominant (59.9%) over those originating from plantations (40.1%). Among the native species of local origin, the prevailing species were synanthropic spontaneophytes (52%), including Acer platanoides and Tilia cordata Mill. Anthropophytes were more abundantly represented by diaphytes (22.7%), followed by kenophytes (10.4%). The most abundant species among diaphytes was Ligustrum vulgare, and among kenophytes - Acer negundo.
A Study on Geographic Information Services Ontology and Its Applications
Authors: Guan Peichao , Zhu Guobin , Yan Bing
Published: May 2018

Based on the relevant studies and successful applications of Geographic information ontology and Web services ontology in the last decade, this paper discusses the utility and research trend of the Geographic information services Ontology in the prospective of Geographic information ontology and the Semantization of the Geographic information services. It proposes the concept of Geographic information services ontology and clarifies the purpose of such construction. It further summarizes the procedures and frameworks of the construction in a Geographic information system.
Visualization Emergency Research Based on Mobile Mapping Technology
Authors: Ming Liao , Fang Pan Yuan
Published: May 2018

Considering the prevention and management of the major emergencies in China and the increasingly severe environmental security situations, a visualization emergency solution, based on a mobile mapping system is proposed. This paper studies the key technologies of a mobile mapping system in emergency management. It considers the design of a total factor and full-texture real map, which is measurable and can be marked through the mobile mapping technology. It also proposes the application of a real map in emergency cases, which has large practical significance.
Study of Rheological Properties of Bituminous Binders in Middle and High Temperatures
Authors: Remišová Eva , Zatkaliková Viera , Schlosser František
Published: May 2018

The bitumen binders in road pavements are exposed traffic loading effect at different climatic conditions. A resistance to these stresses depends on bitumen properties as well. The paper presents rheological properties (G*, δ, ν*) determined and compared for four bituminous binders (unmodified and polymer modified bitumen) at temperature 46 – 60 (80) °C and dynamic viscosity at temperature 130 – 190 °C (Brookfield viscometer). On the basis of viscosity results it is possible to set optimal production and compaction temperatures. Elastic and viscous behavior of binder in the middle temperature is determined in rheometers. The higher value of complex modulus, the stiffer bitumen binder is able to resist deformation. The greater content of elastic components (e.g. polymer in bitumen) varies mainly elastic-viscous properties of primary bitumen.
Parametric Analyses of Dynamic Characteristic of the Cable-Stayed Pedestrian Bridge
Authors: Pańtak Marek , Jarek Bogusław
Published: May 2018

The paper presents characteristics of the structural system and results of dynamic field tests and numerical parametric analyses of three-span, two-pylon, cable-stayed pedestrian bridge with steel-concrete composite deck and spans of 25.5 + 60.0 + 25.5 m. The footbridge is characterized by increased dynamic susceptibility of the elements of the suspension system observed during the everyday operation of the structure. The analyses have shown that the high amplitude vibrations of the pylon back-stay cables change the parameters of the structural system and consequently change the value of the natural vibration frequencies of the structure. In the paper, the selection methodology of parameters of the computational model which allows to correctly determine the natural vibration frequencies of the footbridge has been presented.
2D density model of the Chinese continental lithosphere along a NW-SE transect
Authors: Šimonová Barbora , Bielik Miroslav , Dérerová Jana
Published: May 2018

This paper presents a 2D density model along a transect from NW to SE China. The model was first constructed by the transformation of seismic velocity to density, revealed by previous deep seismic soundings (DSS) investigations in China. Then, the 2D density model was updated using the GM-SYS software by fitting the computed to the observed gravity data. Based on the density distribution of anomalous layers we divided the Chinese continental crust along the transect into three regions: north-western, central and south-eastern. The first one includes the Junggar Basin, Tianshan and Tarim Basin. The second part consists of the Qilian Orogen, the Qaidam Basin and the Songpan Ganzi Basin. The third region is represented by the Yangtze and the Cathaysia blocks. The low velocity body (vp =5.2 – 6.2 km/s) at the junction of the North-western and Central parts at a depth between 21 – 31 km, which was discovered out by DSS, was also confirmed by our 2D density modelling.
The case of historical breeding of Black-Bellied Plover (Pluvialis squatarola) in Central Europe
Authors: Hudeček Jiří J.
Published: May 2018

Black-Bellied Plover (Pluvialis squatarola), is a species breeding in the arctic tundra; in Europe only in Siberian peninsulas on the Russian territory. There is not enough evidence about its historical breeding in Central Europe. Jan Pícha discovered the breeding of Black-Bellied Plover somewhere in Budějovice basin in south Bohemia, possible in the years 1906-1926, possible on the ponds Dvořiště or Volešek. He wrote about in to M. Záleský (visited) and J. Jirsík (in correspondence), and this report has been totally forgotten. Quite approved is Píchaʼs record of Spotted Redshankʼs (Tringa erythropus) breeding; Píchaʼs personality and reliability ensure the correctness of his report. Mating behaviour of Black-Bellied Plover, recorded in South Bohemia also in 1993.
Haplo-Identical Bone Marrow Transplant Protocol using Reduced Intensity Conditioning for Fundeni Clinical Institute
Authors: Zsofia Varady , Daniel Coriu , Gabriel Ghiaur , Jones Richard J.
Published: May 2018

Purpose:

Even if the romanian population is ethnically compact caucasian-type population, many of the patients referred for bone marrow transplantation lack a suitable donor. In order to expand the donor pool and the accesibility to transplant for those who have indications it is necessary to perform haplo-identical bone marrow transplant procedure in Fundeni Clinical Institute. Since 2009 Romania established a National Volunteer Stem Cell Donor Registry (RNDVCSH), the goal was to enlarge the possibility to find HLA-matched unrelated donors (MUD) for patients. This approach offered transplant for only up to 60%patients referred for transplantation in 2014, even we chose one HLA-mismatch donors.

The haploidentical transplant protocol proposed for our institution is based on Sidney Kimmel Comprehensive Cancer Center protocol from Johns Hopkins University School of Medicine. The major milestones of this protocol include: patient eligibility, donor selection criterias, evaluation of the haplo donor, the conditioning regimen plan and additional supportive care, the bone marrow harvest, prophylaxis of graft versus host disease, assessment during and after the transplant.

Donor must be HLA-haploidentical first-degree relatives of the patient with signed consent.

The patient, parents and children are typed at the allelic level for HLA-A, -B,-C,-DRB1 and -DQB1. They will perform also de HLA-antibody search using cross-match test in complement-dependent cytotoxicity.

The conditioning regimen is composed by Fludarabine 30 mg/m2/day (from day -6 to day -2) combined with Cyclophosphamide 14,5 mg/kgIBW/day (from day -6 to day-5) and TBI at 2 Gyîn day -1. In case of lacking TBI procedure at 2 Gy dose in day -1, it could be replaced by two dose of Busulfan iv in day -3 and day-2 (dose=3,2 mg/kgIBW/day) for those with acute and chronic leukemias.

The donor will have general anesthesia,the target yield of marrow is 4 x 10^8 total nucleated cells/kg recipient using his IBW.

The GVHD prophylaxis consisted of post-transplant Cyclophosphamide (PTCy) of 50mg/kgIBW/day in IV administration in day +3 and +4, followed by tacrolimus and mycophenolatemofetil (MMF) beginning day +5. The MMF will be stopped at day+35, the tacrolimus will continue till 6 months after the transplantation.

Conclusion:

One of the most important factors affecting transplantation outcome is proper timing.Therefore, donor availability is an crucial issue. Haploidentical related donors are available for almost all patients, so the use of those donors is a viable alternative.
Quercetin, Menadione, Doxorubicin combination as a potential alternative to Doxorubicin monotherapy of acute lymphoblastic leukemia
Authors: Irimia Ruxandra , Tofolean Ioana Teodora , Sandu Roxana Gabriela , Băran Oana Elena , Ceauşescu Maria Cătălina , Coşoreanu Vlad , Ilie Maria Teodora , Babeş Ramona , Ganea Constanţa , Băran Irina
Published: May 2018

Doxorubicin is a widely used chemotherapeutic drug, effective on patients with acute lymphoblastic leukemia but associated with significant long term cardio-toxicity. Menadione (vitamine K3) and the flavonoid quercetin are known as strong apoptogens in human leukemia Jurkat T cells.

We explored the potential synergic cytotoxic effects of doxorubicin in association with quercetin and Menadione in this cellular model for acute lymphoblastic leukemia.

Cellular viability, apoptosis, necrosis oxidative stress and cellular cycle were determined by flow cytometry utilizing Jurkat lymphoblasts labeled with Annexin V-FITC/7-AAD, CM-H2DCFDA/7-AAD and propidium iodide respectively.

Results indicate a dose-dependent oxidative-stress generation, cell cycle arrest and apoptosis induction by doxorubicin alone, correlated with a decrease of the required doses when the anticancer drug was associated with quercetin and menadione, hence supporting the theory of an additive cytotoxic effect on leukemia cells.

Introducing QC-MD combinations in leukemia doxorubicin-based treatment could significantly increase the treatment’s efficacy. The main mechanism responsible for this effect appears to be the increase in DOX affinity for DNA, which enables lowering of the therapeutic dose.
The Effect of Calcium Chloride and Calcium Lactate on the Yielding of Agaricus bisporus (Lange) Imbach
Authors: Kałużewicz Alina , Górski Romuald , Sobieralski Krzysztof , Siwulski Marek , Sas-Golak Iwona
Published: May 2018

The aim of the research was to assess the influence of calcium chloride and calcium lactate irrigation on the yield volume and dry matter content in two champignon strains, ie Amycel 2200 and Italspawn F59. When both strains were irrigated with calcium lactate, there was a significant decrease observed in the yield when the concentration of the solution was 0.6%. On the other hand, when calcium chloride was applied to the Italspawn F59 strain, there was a significant decrease in the yield when the concentration was as low as 0.4%, whereas the yield of the Amycel 2200 strain dropped when the concentration of calcium chloride was 0.6%. The irrigation with calcium chloride and calcium lactate had influence on the content of dry matter in the champignon carpophores. When the solutions under investigation were applied at concentrations of 0.4 and 0.6%, there was a significant increase observed in the content of dry matter in both strains.
Mixing of Biomass and Coal in a Static Mixer as an Example of Technological Solutions Involving Implementation of Renewable Energy Sources
Authors: Królczyk Jolanta B. , Rezwiakow Andrzej , Tukiendorf Marek
Published: May 2018

The purpose of this article is to demonstrate possibilities of mixing coal with biomass using static mixers. The paper present simple and inexpensive methods for producing fuel mixes for heat-generating plants equipped with stoker-fired boilers of power ranging from 3 up to 50 MW. Static mixer proposed in this article may constitute an alternative for currently used solutions in production facility. Based on statistical analysis, the article demonstrates that five mixing elements of the mixer is optimal number to ensure best biomass (chips and pellets) concentration distribution in a mixture with fine hard coal.
Commercial Diplomacy In Serbia: Characteristics And Areas For Improvement
Authors: Penev Slavica , Udovič Boštjan , Đukić Mihajlo
Published: May 2018

The paper analyses the challenges of modern commercial diplomacy (CD), which became more relevant than it was in the pre crisis period. In this context, the authors analyzed the chronology of implementation of CD in Serbia, scope and efficiency of its activities, and the areas for improvement. Some of their findings, related to the efficiency and challenges in CDs activities, are based on the questionnaire conducted among 25 Serbian CDs. The paper concludes that in order to increase the efficiency of commercial diplomacy, coordination of the activities of the responsible institutions should be improved, to avoid overlapping in their work and to rationalize use of limited resources. However, the authors emphasised that the space for contribution of commercial diplomacy to the increase of export and FDI is insufficient, due to limited export potential and poor investment climate in Serbia. The authors conclude that in order to increase the efficiency of commercial diplomacy in export promotion area, it is important to implement the necessary reforms, which will result in the restructuring of Serbian economy, make it more competitive and export oriented. To increase the inflow of FDI to Serbia, it is necessary to create a business friendly investment climate.
Accouting and marketing dimensions of innovations
Authors: Dyhdalewicz Anna , Widelska Urszula
Published: May 2018

Innovations are an important, although imprecise conceptual category. They are perceived differently depending on the accepted scientific perspective. The article verifies the concept of innovation in terms of marketing and accounting. The main aim of the paper is to identify problems and formulate preliminary research hypotheses connected to the integration of the accounting and marketing functions of an enterprise within the context of the assessment of innovative activities conducted by the entity. Additionally, it is the authors’ intention to draw attention to similarities and differences that occur between the regulations of the national accounting law and the approach of marketing within this domain. For the purposes of the research it has been hypothesized that the integration of the accounting and marketing functions of en enterprise concerning innovation is limited because of different perceptions of sources and results of innovation within these two fields. Assessments of the innovativeness of the same enterprise from the perspective of marketing and from the perspective of accounting are different. This aim has been realized through the use of scientific description based on the analysis of literature concerned mainly with marketing innovation. The perspective of accounting innovation was also analyzed through a literature study and using a comparison study of chosen accounting regulations contained in the Polish Accounting Act and the International Accounting Standard 38 „Intangible Assets”. In conclusion it should be stated that accounting has not defined the concept of „innovation” nor, for the purposes of financial reporting, has not isolated innovation as an asset. In accounting, assets associated with the concept of innovation include intangible assets and tangible resources in fixed assets. Considering the presented approaches to innovation a distinct relationship on the type of incurred expenditures can be noticed: whether the expenses had been incurred for internally generated assets or for their acquisition. Only acquired resources and costs of completed development and development work in progress are a common part for these concepts. The presented initial stage of research also confirmed that from the perspective of accounting and marketing the assessment of the innovation level of an enterprise is not identical. It is assumed that the integration of the accounting and marketing functions within a company may have a positive effect on the process of information management.
Influence of resting and pine sawdust application on chemical changes in post-agricultural soil and the ectomycorrhizal community of growing Scots pine saplings
Authors: Małecka Monika , Hilszczańska Dorota
Published: May 2018

Changes in chemical compounds and in ectomycorrhizal structure were determined for Scots pine growing on post agricultural soil lying fallow for 3, 6 and 15 years, after amendment with pine sawdust. Soil without any amendments was used as the control treatment. Comparing the ectomycorrhizal structure 15 years after the application of pine sawdust revealed no significant differences in abundance or species richness between soil with and without organic enrichment. The results showed that the ectomycorrhizal status depends on soil conditions (soil pH, nitrogen content), which remain unaffected by saw dust application. In all treatments, the most frequently occurring ectomycorrhizae genera were Dermocybe, Hebeloma, Suillus, Tomentella and Tricholoma. Two species (Paxillus involutus, Amanita muscaria) were specific to the control plots that lay fallow for 15 years.
Variability of morphological features, bud burst and flowering of Norway spruce (Picea abies [L.] Karst.) in the seed orchard of the Bielsk Forest District
Authors: Mioduszewski Sławomir , Rzońca Marek
Published: May 2018

The main aim of this paper was to characterize Norway spruce clones in terms of bud burst, flowering and morphological features. Observation and measurements were carried out in the Norway spruce seed orchard of the Bielsk Forest District in the north-eastern part of Poland. The seed orchard was established in 1989 and consists of 428 grafts of over 37 trees from the Białowieża Primeval Forest. An assessment of bud burst, stem forking, stem form, crown width, branch thickness, vitality, flowering and fructification as well as diameter measurements was done in 2013 and 2014. The results showed variability of morphological features among different clones as well as within individual clones. Differences among clones in spring bud development, stem form and branch thickness were statistically significant. Additionally, a positive correlation between male and female flowering was observed. The research also confirmed an influence of the healthiness of the grafts on seed production with trees in a weakened state producing more seeds.
Development of the foreign direct investments in the transitive economies: Example of Central-European Countries (CEC)
Authors: Hlaváček Petr
Published: May 2018

The paper focuses on the foreign direct investments (FDI) in the Central Europe and on the development changes among the individual countries. The paper follows from the work (Gauselmann et al. 2011) dealing with the development of the transient economies with focus on the role of the FDI. The objective of the paper is identification of the impact of the FDI on the economic growth and economic performance during the post-transformation era where differences among the countries at the beginning of the monitored period in 2000 and at the end of 2011 are evaluated based on data of United Nations Conference for Trade and Development. The development of FDI following 2000 was positively influenced by new system of the investment incentives for the foreign investors, accession of the countries to the European Union, it increased their credibility for foreign investors. High inflow of foreign direct investment ended with beginning of the economic crisis in 2008. Current trend in FDI is below its level before the economic crisis, and their amount increase only by few percent per year.
Investigation of copper and gold prospects using index overlay integration method and multifractal modeling in Saveh 1:100,000 sheet, Central Iran
Authors: Rezaei Somayeh , Lotfi Mohammad , Afzal Peyman , Jafari Mohammad Reza , Meigoony Mojtaba Shamseddin , Khalajmasoumi Masoumeh
Published: May 2018

This study aims at prospecting copper and gold promising areas in Saveh 1:100,000 sheet, situated in Urumieh-Dokhtar magmatic belt (Central Iran). Geographic information system (GIS) is effective in recognition of probable mineral resources by collecting, processing, exploration layer weighting and integrating thematic maps. As there is no certainty in different geological phenomena, modeling and integrating information layers are used to obtain suitable results for determining potential areas. In this study, index overlay method, which is a combination of software processing and expertise knowledge, was used. The survey layers consist of the lithologic units, geophysical data, mineralization, faults and structures and alteration. For more exact survey, concentration-area (C-A) fractal modeling was applied to the map of results obtained from integration. Applying fractal model to this map, the results of the original map were prioritized and became more limited. In the end for assessing the validity of determined promising areas, the results were compared with geochemical anomaly maps of stream sediments and also field observation was performed. Areas with high exploration priority with limited extend exist in center, west and some parts of NW, conformed to granodiorite intrusives and also next priority exists in center, west, NE and NW conformed to granite, diorite, and also subvolcanic rocks respectively. These prioroties are related to fault systems. In order to perform X-ray Diffraction (XRD), Inductively Coupled Plasma – Mass Sepctrometry (ICP-MS) analyses and microscopic studies, lithogeochemical samplings were done. All investigations indicate the possibility of pyrite, chalcopyrite and galena epithermal mineralizations resulted from post magmatic fluids, and also secondary products like hematite, goethite, and malachite as a result of oxidation processes in these areas.
CO2 Utilization For Mechanochemical Carbonation Of Celestine
Authors: Turianicova Erika
Published: May 2018

Natural celestine (SrSO4) has been succesfully transformed into strontianite (SrCO3) via fast one-step mechanochemical carbonation utilizing gaseous CO2. The process was realized in the environment enriched with LiOH or NaOH additives. The mixtures were milled in a high-energy planetary ball mill for 40 min. The phases formed during the milling were characterized by different characterization techniques, such as X-ray diffraction (XRD) and infrared spectroscopy (FT-IR). The presence or absence of carbon or sulphur in the products was confirmed by a CHNS analysis.
Influence of Intercept Valves on Control of Multiple Stages Steam Turbines During the Switching into the Island Operation
Authors: Laštovka Ladislav , Hejtmánková Pavla
Published: May 2018

This paper presents control of a multiple stages steam turbine which is switched into the island operation. The frequency in an electrical grid is stated on nominal value which is in UCTE grid 50 Hz. When deviation of frequency is higher then 0.2 Hz, the switching of particular steam units into the island operation is only the chance how to maintain the supply of, at least, some small grids. The other possibility how to keep power units in operation, to be prepared for the next synchronization to the grid, is to switch them to operation status in which they supply only their self-consumption. This change of the operating state is the most dynamic load change for the control system of the unit. The multiple stages turbines are equipped with high pressure hydraulic valves for steam turbine governing. Influence of the intercept valve on steam turbine control during the switching process into the island operation is examined in Matlab Simuling software.
Predictors of Gaming Behavior among Military Peacekeepers – Exploring the Role of Boredom and Loneliness in Relation to Gaming Problems
Authors: Myrseth Helga , Kjellevold Olsen Olav , Kristian Borud Einar , Åge Strand Leif
Published: May 2018

The aim of the current study was to explore gaming problems in post-deployment veterans and to investigate whether boredom and loneliness can predict levels of gaming problems. The general well-being of veterans post their deployments to war zones is linked to an array of negative health consequences, and veterans may be at risk for developing gaming problems after homecomings. Problems that may be related to engagement in gaming include coping with negative emotions, such as boredom and loneliness, which are often faced by homecoming veterans as well. The sample in this study comprised Afghanistan veterans (N = 246), with a mean age of 37.5 years (standard deviation = 9.6 years), and 8.8% of the veterans showed symptoms indicative of problem gaming. This is not higher than that found in the general adult population in Norway. Logistic regression analyses showed that boredom proneness (lack of internal stimulation) and enhancement motivation were independent significant predictors of gaming problems, after controlling for age, gender, coping motivation, social motivation, anxiety, depression, loneliness, lack of external stimulation, hazardous drinking, and combat exposure. These factors accounted for as much as 65.8% of the variance in gaming problem status. We conclude that veterans who are highly motivated by enhancement motives and score low on lack of internal stimulation may be prone to developing gaming problems.