bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of a modified biological flocculant in total nitrogen treatment of leather wastewater
Authors: Zhang Yizhuo , Yang Qinhuan , Gao Hongxia , Zhao Yang , Tang Xuan , Zhao Changqing , Fang Chunyu
Published: May 2021

Leather wastewater harms the ecological environment and human health. In this study, a modified bio-flocculant was prepared to facilitate treatment of leather wastewater. A bio-flocculant produced by Bacillus cereus was combined with amphoteric starch and modified using a cerium ammonium nitrate initiator. Single factor optimization and orthogonal optimization were used to determine the optimal preparation conditions as follows: amphoteric starch-to-flocculant ratio = 22:30; reaction temperature = 64 °C; initiator dosage = 2.00%; reaction time = 15 min; stirring speed = 600 rpm; and flocculation system pH = 8.0. At a dosage of 1 g/L added to simulated leather industry wastewater, the flocculation efficiency (98.17%) and the total nitrogen removal efficiency (100.00%) of modified bio-flocculant was superior to that achieved by 1 g/L of unmodified bio-flocculant (72.16% and 50.00%, respectively), amphoteric starch (8.50% and 0.00%) and polyacrylamide (95.55% and 75.00%). Analysis of natural and flocculated precipitates in the wastewater showed that the modified bio-flocculant significantly changed several characteristics of the flocculated particles; in addition, it promoted the removal of nitrogenous substances in the process of denitrification. These changes helped explain the material's flocculating ability. The results confirmed that the modified bio-flocculant was an effective additive for treating leather wastewater.
Microalgae cultivation in wastewater effluent from tilapia culture pond for enhanced bioethanol production
Authors: Bhuyar Prakash , Trejo Marlen , Dussadee Natthawud , Unpaprom Yuwalee , Ramaraj Rameshprabu , Whangchai Kanda
Published: May 2021

The large number of wastewaters are generated because of the various production processes. Vegetable and fish processing can be considered an important industry for wastewater generation. The essential method for completing this waste is to digest the organic matter using anaerobic digestion followed by aerobic wastewater treatment processes; however, wastewater from tilapia culture pond retains considerable quantities of inorganic substances, particularly nutrients like nitrogen and phosphorus. The optimal conditions for cultivating Chlorella vulgaris from wastewater treatment effluent from tilapia culture pond were investigated in this study. The appropriate conditions were found to be 10% initial stock suspension, 20 cm depth, and 12 days of culture conditions. C. vulgaris had an optical density of 0.649, a cell density of 17.68 × 105 cells/mL, and biomass of 0.376 ± 94.21 mg/L after cultivation. Discharged wastewater from the fishpond was utilized for the improved growth of microalgae and obtained biomass was used for bioethanol production. This study verified that fishpond wastewater is the best source of nutrients for algal mass production and biofuel applications.
Step economy in the Stereoselective Synthesis of Functionalized Oxindoles via Organocatalytic Domino/One-pot Reactions
Authors: Bortolami Martina , Leonelli Francesca , Feroci Marta , Vetica Fabrizio
Published: May 2021

:

Oxindoles are an important class of heterocyclic scaffolds widely present in natural products and bioactive compounds. For this reason, a plethora of methodologies for the stereoselective synthesis of enantioenriched oxindoles has been studied over the years. Among all the reported synthetic strategies, organocatalysis has proven to be a powerful tool for the asymmetric synthesis of this class of compounds being a step- and atom-economical, environmentally friendly, and non-toxic approach. This review will outline the application of asymmetric organocatalysis in the synthesis of chiral oxindole-based structures, relying on domino/one-pot reaction sequences in a step-economical fashion.
Differences Among Sexes in Blood Pressure: A Combinatorial Consequence
of the Differences between RAAS Components, Sex Hormones,
and Time Course
Authors: Yang Xiaomei , Liu Shien , Zhang Zhongming
Published: May 2021

:

For all lives regardless of sex, the longitudinal increase in blood pressure (BP) with age
is attributed to lifestyle, internal environments like systemic brain-derived neurotrophic factor (BDNF)
signaling, and external environments, allowing the individuals to better adapt to the developmental
and environmental changes. Basic levels of renin-angiotensin-aldosterone system (RAAS)
components in males and females define the fundamental sex difference in BP, which may be set
by prenatal programming and the profound influence of BP after birth. The innate sex difference in
BP is magnified during puberty growth and later on, affected and modified by menopause in women.
At the age of 70 and older, blood pressure has been found to be similar for men and women. Understanding
the prenatal setup and development of sexual dimorphism in BP may provide preventative
therapeutic strategies, including timing and choice of drugs, for individuals with abnormal BP.
Experimental Investigation of Shear Strength for Steel Fibre Reinforced Concrete Beams
Authors: Demakos Constantinos B. , Repapis Constantinos C. , Drivas Dimitros P.
Published: May 2021

Aims:

The aim of this paper is to investigate the influence of the volume fraction of fibres, the depth of the beam and the shear span-to-depth ratio on the shear strength of steel fibre reinforced concrete beams.

Background:

Concrete is a material widely used in structures, as it has high compressive strength and stiffness with low cost manufacturing. However, it presents low tensile strength and ductility. Therefore, through years various materials have been embedded inside it to improve its properties, one of which is steel fibres. Steel fibre reinforced concrete presents improved flexural, tensile, shear and torsional strength and post-cracking ductility.

Objective:

A better understanding of the shear performance of SFRC could lead to improved behaviour and higher safety of structures subject to high shear forces. Therefore, the influence of steel fibres on shear strength of reinforced concrete beams without transverse reinforcement is experimentally investigated.

Methods:

Eighteen concrete beams were constructed for this purpose and tested under monotonic four-point bending, six of which were made of plain concrete and twelve of SFRC. Two different aspect ratios of beams, steel fibres volume fractions and shear span-to-depth ratios were selected.

Results:

During the experimental tests, the ultimate loading, deformation at the mid-span, propagation of cracks and failure mode were detected. From the tests, it was shown that SFRC beams with high volume fractions of fibres exhibited an increased shear capacity.

Conclusion:

The addition of steel fibres resulted in a slight increase of the compressive strength and a significant increase in the tensile strength of concrete and shear resistance capacity of the beam. Moreover, these beams exhibit a more ductile behaviour. Empirical relations predicting the shear strength capacity of fibre reinforced concrete beams were revised and applied successfully to verify the experimental results obtained in this study.
Combating Modern Slavery: The Strategy of Indonesian Government to Protect Migrant Workers
Authors:   Universitas Airlangga, Puspitasari Irfa
Published: May 2021

Economic migration create opportunities as well as humanitarian challenge. People travel across national boundary looking for work in the country destination. They would benefit their hosted as well as sending high amount of remittance for home. However, those dream were not applicable to all economic migrant when some of them fall victim into human trafficking. This research would investigate the strategy as well as challenges by Indonesia government and NGOs to promote protection of Indonesian migrant worker. It is imperative to evaluate state policies, state diplomacy, transnational advocacy network, and the nature of companies as agent of service provider. It would show how current practices and law has loopholes that create challenges for public private partnership to provide adequate support for Indonesian migrant worker. Investigation is conducted through interview, observation and literature review. The struggle to end modern slavery shall be one among priority in protecting civilian abroad, if the government is serious to minimize economic inequality and to change itself into welfare nation.
Exploring Youth Political Participation: K-Pop Fan Activism in Indonesia and Thailand
Authors:   Universitas Brawijaya, Andini Amalia Nur , Akhni Ghaziah Nurika ,   Ritsumeikan University
Published: May 2021

This paper explores K-pop fans political participation by looking at recent fan activism that happened in Indonesia and Thailand. Since the US fans participation in BLM campaign and ‘sabotaging’ of Trump’s Tulsa campaign rally, the K-pop fans community has made headlines on mainstream media as part of contemporary political discourse. Similar situation is also encountered in Southeast Asia where Korean popular culture has been consumed for decades and has large following. K-pop fans in Indonesia and Thailand have participated in various forms of activism supporting humanitarian causes through donations, criticizing new laws, or protesting against the government. Focusing on four key areas of analysis: the intersection between cultural and civic/political participation, the tension between participation and resistance, affect and collective identity, and impacts; this paper aims to explain how fandom may act as a powerful force that bridges cultural consumption and political participation amongst youths in the era of media convergence.
Analisis Pengaruh P-Delta Effect Terhadap Perbedaan Ketinggian Struktur Gedung Tahan Gempa (Studi Kasus : Non-Highrise Building)
Authors:   Institut Teknologi Adhi Tama Surabaya, Istiono Heri , Ramadhan Azhar Yusuf ,   Institut Teknologi Adhi Tama Surabaya
Published: May 2021

The need for earthquake resistant buildings in Indonesia is something that needs to be considered. Considering that Indonesia is an earthquake prone area. A building structure must be designed to be able to withstand lateral loads such as earthquakes within the limits set by the code/standards. For conservative reasons analysis of the P-Delta Effect needs to be considered because the building development ratio will always increase every time. according to SNI 1726-2019 the P-Delta effect is only required for the design of tall buildings. In this case, the P-Delta effect will be calculated in the modeling of non-high-rise buildings and get the results that P-Delta Effect increased story forces: moment of the building under 10%.
Ideas of Muslim History Rethinking in the Works by Arab Intellectuals of the Late 20th – Early 21st Centuries
Authors:   St. Petersburg State University, Oleg Aleksandrovich Sokolov
Published: May 2021

In the 21st century, Muslim reformist thought is going through a period of rapid devel-opment, during which the ideas of the renovators of the 19th – 20th centuries are being trans-formed and developed. In the late 20th – early 21st centuries, major Arab intellectuals put for-ward various ideas for rethinking the Muslim reformist paradigm by changing approaches to the study and understanding of the history of the Muslim Ummah and overcoming the non-historicity of discourse. Within the framework of this article, for the first time, an attempt was made to classify the approaches of the largest Arab representatives of the Muslim reformist movement to the study of the history of Muslim civilization from the point of view of changing the paradigms of modern humanitarian knowledge. Muhammad al-Ashmawi, within the frame-work of the positivist concept, advocated a reinterpretation of the era of the “righteous caliphs”. Faraj Fuda, who stuck to a post-positivist position, put forward the idea of an inductive rethink-ing of Muslim history. Muhammad al-Jabri, being a representative of structuralism, proposed to build a clear referential framework for the periodization of the history of Muslim civilization. Finally, Muhammad Arkun, analyzing the ways of solving the indicated problem, relied on the post-structuralist ideas of “applied Islamology” based on the progressive-regressive historical method. The presented classification clearly demonstrates the diversity of modern Muslim re-formist thought and the multi-stage nature of its development. The proposed division of ap-proaches to the study and understanding of the history of the Muslim Ummah by Arab authors can be further correlated with the typology of the development of reformist ideas in other re-gions of the Muslim world.
Life and Activities of Garifullah Ishan Gainullin (1894–1984)
Authors:   Kazan Federal University, Rashid Ilyazovich Malikov
Published: May 2021

The article is the result of extensive research and generalization of available sources and literature that reflect the life and spiritual activities of Garifulla Ishan Gainullin – one of the most authoritative religious figures of the Middle Volga region of the Soviet period. He was the last Tatar Sheikh of the Naqshbandi tariqah, who was related to Dagestani Sheikh Bayazid Ishan Khairullin through Zainulla Ishan Rasulev. In his youth, he received a good theological educa-tion in a pre-revolutionary madrasah, passed many trials and overcame hardships of his time on his life's path. Despite the difficult situation in the country, he managed to gain additional reli-gious knowledge, spiritually improved himself and became an authoritative spiritual mentor (Ishan) in the Middle Volga region. Published for the first time are personal photos and docu-ments of Ishan, with some of them used in his biography. In Russian historiography, the person-ality of Garifulla Ishan Gainullin has not been studied in detail and many of its aspects are little known to general readers.
Efecto tributario de las donaciones en el impuesto sobre la renta y complementarios
Authors:   Corporación Universitaria Americana, Hernández-Belaides Hernán José
Published: May 2021

Esta investigación tiene como objetivo dilucidar las incidencias tributarias y el efecto que tienen las donaciones en el impuesto sobre la renta y complementarios de los contribuyentes que hacen la donación. Es común en-contrar una serie de opiniones al respecto que riñen con las normas tributarias o que simplemente no tienen un real asidero legal, lo cual se manifiesta en la desinformación de aquellas personas altruistas que buscan por este medio contribuir con causas nobles y de interés, generalmente, de poblaciones vulnerables. Se analizan las leyes y normas relacionadas y dentro de un contexto legal y práctico, se harán las precisiones tendientes al cumplimiento de los objetivos.
Economía Naranja: ¿cuánto se puede exprimir?
Authors:   Universidad del Atlántico, Coronel Montaguht Yessy Lorena , Pablo Dolcey Juan ,   Universidad del Atlántico, Morales González Kenkin ,   Universidad del Atlántico
Published: May 2021

El presente artículo constituye el resultado del ejercicio de reflexión de la participación e importancia económica que viene desarrollando el sector denominado Economía Naranja. El análisis abordó un enfoque histórico, uno desde su aporte a la innovación, y uno desde la creciente inclusión de bienes y servicios de este sector en la canasta de consumo del país. Por último, ante la preocupación por el grado de saturación que algunos servicios de este sector en-frentan, se propone medir un factor de desgaste cuyos resultados aporten a las decisiones de políticas y de inversión en la materia
Incidencia de la dinámica organización al en la gestión de nuevo conocimiento en las universidades
Authors:   Universidad Libre Seccional Barranquilla, Ariza Yuleida , Monsalve Peláez Magda Andrea ,   Universidad Simón Bolívar, Gamboa Caicedo Nery ,   Universidad Simón Bolívar
Published: May 2021

En momentos actuales y ante el surgimiento de nuevas tecnologías con innovadoras tendencias en las que el conocimiento es eje fundamental para promover desarrollo en las sociedades, se hace necesario comprender las formas de transferirlo convirtiéndolo en valor agregado para las empresas; es por ello que el presente escrito se propone estudiar la relación entre las dinámicas organizacionales que inciden en el desarrollo de nuevo conocimiento en las universidades, como fuente interna para generar ventaja competitiva. En su elaboración se utilizó el método descriptivo, apoyado en la revisión documental, con enfoque cualitativo, el cual aporta profundidad al estudio, necesario por tratarse de un fenómeno con escasos antecedentes y alto impacto social, justificando su pertinencia y validando su acometido de responsabilidad social. Como hallazgos se destaca que las capacidades organizacionales representan un factor predominante en el desarrollo de nuevo conocimiento, por cuanto repensarlas implica procesos de investigación permanente. Se concluyó que dentro de los factores que inciden en la dinámica organizacional para la creación de nuevo conocimiento, se encuentra la planeación transformacional, capaz de generar acciones que respondan al enfoque sistémico de la sociedad, cuyos conocimientos innovadores aportan variadas miradas de solución a problemáticas complejas
Teorías de desarrollo económico y desarrollo económico regional: un enfoque conceptual
Authors:   Universidad del Atlántico, De la Cruz Almanza Sadan
Published: May 2021

El objetivo principal de este trabajo es discutir las principales teorías del desarrollo económico y desarrollo económico regional, con una perspectiva histórica en la evolución de los conceptos y la articulación de los mismo con la teoría económica. Metodológicamente, se aplicó una revisión bibliográfica, permitiendo realizar una minuciosa presentación de los conceptos y las teorías siguiendo una línea de tiempo. Las principales conclusiones, tratan sobre la importancia de estas teorías en el orbe de la economía moderna, y la contribución de las diferentes escuelas de pensamiento económico y los autores de cada época.
How to deal with conflict without using violence? Analysis of the colombian state and the law of victims, taking away arguments to illegal armed groups
Authors:   University of Kent, Cano Holguín Nelson
Published: May 2021

The Colombian conflict has been one of the longest running disputes in the Western world. Although the signing of the peace treaty in 2016 gave hope back to the territory, this process did not happen overnight, so it was necessary to go through a historical journey to get the results today, where one of its fundamental milestones was the law of victims and the framework for peace. Through a review of the literature, this article seeks to analyze the impact on the Colombian conflict and the dynamics of the actors involved from the perspective of the law of victims. Among the most significant findings is that the Victims’ Law should not be seen as a panacea to solve all the country’s problems. Few recognize that it is a first step in the right direction, and the government’s courage to take it must be stressed. In that sense, the authorities must show good intentions, imagination and political will to allow the military response on the one hand, and generate and implement initiatives and policies with facts on the other hand.
Análisis sobre cApAcidAdes dinámicAs
Authors:   Corporación Politécnico Costa Atlántica, Porto Solano Roberto , Eljaiek Olier Rachid ,   Universidad Autónoma del Caribe, Rodríguez Lafaurie Prissila ,   Universidad autónoma del caribe, Díaz Osorio Julianys ,   Universidad Autónoma del Caribe
Published: May 2021

Las capacidades dinámicas son el potencial de la empresa para resolver metódicamente los obstáculos constituidos por las ocasiones y apercibimientos para tomar juicios oportunos, orientados al mercado para cambiar los cimientos de sus recursos. Se puede tratar con una amplia variedad de campos y variaciones o renovaciones de las capacidades dinámicas aplicadas a nivel empresarial. Este artículo se centra en una revisión sobre varias capacidades dinámicas que se utilizan frecuentemente en el ámbito empresarial y la posibilidad de generar otras a partir de las existentes. Existen una gran varie-dad de DC (Dynamic Capabilities) o capacidades dinámicas que pueden usarse como la de absorción, de explotación del conocimiento, de innovación, de aprendizaje, de combinación del conocimiento, de generación del conocimiento y la de creación de nuevas capacidades, etc. Este trabajo también trata con un estudio sobre algunas de estas técnicas de uso común que se están utilizando de manera generalizada
El terrorismo internacional como detonante de políticas securitizadoras
Authors:   Universidad del Norte, Fontalvo Grueso Tatiana , Fuentes María Paula ,   Universidad del Norte
Published: May 2021

Este artículo busca estudiar el fenómeno de la securitización que se ha venido presentando en Bélgica, Estados Unidos, Francia y Reino Unido, entre otros países tras los atentados a las torres gemelas de la ciudad de Nueva York en 2001 y que se ha intensificado con el nacimiento del grupo terrorista Estado Islámico y sus ataques internacionales. De esta manera, a través de cinco factores identificados duran-te la investigación, se pretende analizar las razones que utilizan los Estados para legitimar la ejecución de normas, leyes y ordenamientos que securitizan el país en busca de la prevalencia de su seguridad nacional.
Lean Management y su implementación en el sector industrial: fortalezas, debilidades y retos por abordar en el contexto de producción colombiano: una revisión
Authors:   Universidad Autónoma de Sinaloa, Ovalles Toledo Luiz Vicente
Published: May 2021

La metodología de gerenciamiento ágil (Lean Management) ha ganado especial relevancia en el sector industrial de Colombia, considerada su aplicación en los procesos de producción nacionales y el de-sarrollo de estrategias de mejoramiento continuo operacional en miras de dos objetivos principales: minimización de pérdidas de tiempo y costos de operaciones no productivas; y maximización de lucro, mediante el análisis, evaluación y seguimiento de los procesos de producción. La presente investiga-ción trabaja metodológicamente un abordaje bibliográfico, analítico y crítico de los cinco principales sectores con gran participación porcentual del Producto Interno Bruto colombiano y gerenciamiento ágil para cada contexto: el sector alimenticio (Lean Management Food industry), educación y mejora-miento (Lean Management Improve Education), salud (Lean Management in Healthcare), manufactu-ra (Lean Manufacturing) y construcción civil (Lean Construction). A partir de lo anterior, fue elaborada una investigación descriptiva de las principales fortalezas, debilidades y retos en el contexto de pro-ducción colombiano y casos de éxito para dichos sectores de la industria. Los resultados obtenidos permiten evidenciar diferentes perspectivas de implementación de la metodología Lean Management y su impacto potencial en aumento del sector industrial en el desarrollo de competencias de productividad, rentabilidad y participación industrial nacional
Alternativas ante la dependencia del petróleo en las exportaciones. Un estudio al caso colombiano
Authors:   Universidad Autónoma de Sinaloa, Flórez Vizcarra Martina , Venecia Fontalvo José Manuel ,   Corporación Universitaria Empresarial de Salamanca, Morales Espinosa Roberto Antonio ,   Corporación Universitaria de la Costa (CUC)
Published: May 2021

Esta investigación se realiza con el fin de identificar otras oportunidades económicas en la balanza comercial de Colombia; según estudios realizados por Campetrol el país solo tendría reservas petroleras durante los próximos seis años, lo que demuestra la fuerte dependencia del crudo en los ingresos de la nación y en sus exportaciones. La investigación se centró en analizar la importancia del petróleo para Colombia, se estudiaron los distintos recursos con los que se puede transformar la economía del país siguiendo los modelos económicos implementados en otras naciones que han crecido económicamente sin necesidad de la explotación de hidrocarburos.
Experience of Peer Bloggers Using a Social Media Website for Adolescents With Depression or Anxiety: Proof-of-Concept Study
Authors: Karim Sana , Hsiung Kimberly , Symonds Maria , Radovic Ana
Published: May 2021

Background

Supporting Our Valued Adolescents (SOVA) is a moderated and anonymous social media website intervention. SOVA ambassadors are adolescents and young adults (AYA) asked to write monthly blog posts and comments on others’ posts on topics surrounding mental health.

Objective

This study aims to understand the feasibility and acceptability of peer blogging for a moderated mental health intervention website and explore whether bloggers—AYA who self-report symptoms of depression and anxiety—experience potential benefits.

Methods

AYA aged 14 to 26 years with a self-reported history of depression or anxiety were recruited to the SOVA Peer Ambassador Program. Participants were asked to write one blog post a month and comment at least four times a month on other blog posts, for which they were compensated for up to US $15 monthly. Outcome variables measured at baseline and 3 months after intervention included website usability and feasibility, depressive symptoms, anxiety symptoms, mental health treatment history, cybercoping, personal blogging style, self-esteem, loneliness, mental health stigma, social support, and positive youth development characteristics. Open-ended questions were asked about their blogging acceptability and usability.

Results

Of 66 AYA showing interest and completing onboarding, 71% (47/66) wrote at least one blog post, with an average of 3 posts per person. A sample of 51% (34/66) of participants completed a 3-month survey for the full analysis. Almost all 34 participants were satisfied with the experience of blogging (32/34, 94%) and rated the website usability as good (80.1, SD 14.9). At 3 months, self-esteem scores increased by 2.1, with a small-medium effect size (P=.01; Cohen d=0.45), and youth competence and confidence increased by 0.7 (P=.002) and 1.3 (P=.002), with medium effect sizes (Cohen d=0.62 and 0.60), respectively.

Conclusions

A blogging intervention for AYA with a history of depression or anxiety was feasible with regular and active engagement and shows evidence in a one-sample design for positive changes in strength-based assets—self-esteem, competence, and confidence—which map onto resilience.
Studi Docking Molekuler Senyawa Dalam Minyak Atsiri Pala (Myristica fragrans H.) Dan Senyawa Turunan Miristisin Terhadap Target Terapi Kanker Kulit
Authors: Pratama Alfian Bagas , Herowati Rina , Ansory Hery Muhamad
Published: May 2021

Kanker kulit adalah penyakit di mana kulit kehilangan kemampuannya untuk regenerasi dan tumbuh secara normal. Penyebab umum terjadinya kanker kulit adalah intesitas paparan sinar UVB. Penelitian terdahulu telah membuktikan kandungan senyawa di dalam minyak atsiri pala (Myristica fragrans H.) khususnya miri stsin memiliki khasiat sebagai antioksidan dan efek cytotoxic. Telah dilakukan skrining target molekuler dari kandungan kimia minyak atsiri pala beserta turunan miristisin-nya terhadap target molekuler antikanker kulit antara lain Heat Shock Protein 90 (HSP90A), Prostaglandin Synthase 2 (PTGS2) dan Dihydroorotate Dehidrogenase (DHODH), dan memprediksi interaksi senyawa dari ke 61 ligan uji dengan target molekuler tersebut, kemudian dilakukan docking molekuler menggunakan perangkat lunak PyRx 0.8. Hasil penelitian menunjukkan bahwa senyawa dalam minyak atsiri pala yaitu Guanicin memiliki nilai ΔGbind yang baik pada  HSP90A dengan nilai -8,2 kkal/mol. Hasil docking antara protein PTGS2 dan DHODH dengan ligan baik dari senyawa dalam minyak atsiri pala maupun senyawa turunan miristisin menunjukkan bahwa hampir semua ligan dapat berinteraksi dengan kedua target dengan ligan yang nilai ΔGbind paling kecil dan memiliki model interaksi terbaik dari senyawa minyak atisi pala adalah asam dihidroguaiaretik, dengan nilai ΔGbind secara berurut-urut sebesar  -8,1 kkal/mol dan -9,3 kkal/mol.
Rasionalitas Pendosisan Ketorolak pada Pasien Geriatri Dengan Penurunan Fungsi Ginjal Rawat Inap di RSUD Benyamin Guluh Kabupaten Kolaka Sulawesi Tenggara
Authors: Saputro Syaifullah , Wahyono Djoko , Yasin Nanang Munif
Published: May 2021

Ketorolak merupakan NSAID yang utamanya dieliminasi melalui ginjal yang membutuhkan penyesuaian dosis pada pasien  geriatri dengan penurunan fungsi ginjal. Penelitian ini bertujuan untuk mengetahui profil rasionalitas pendosisan ketorolak, menganalisis hubungan antara rasionalitas pendosisan dengan efektivitas terapi serta kejadian efek samping pada pasien geriatri rawat inap dengan penurunan fungsi ginjal. Penelitian dilakukan dengan rancangan cross-sectional. Pengambilan data secara retrospektif  melalui penelusuran rekam medis pasien geriatri rawat inap RSUD Benyamin Guluh periode 2015-2020. Data yang diamati berupa regimen pengobatan, serum kreatinin, efektivitas terapi dan efek samping. Rasionalitas pendosisan dinilai berdasarkan kesesuaian dosis dengan referensi/formula Guisti Hayton. Efektivitas terapi tercapai jika penurunan VAS <50% dan kejadian efek samping dapat diamati pada catatan perkembangan pasien pada rekam medis. Uji statistik Chi Square dilakukan untuk mengetahui hubungan antara rasionalitas pendosisan dengan efektivitas terapi dan efek samping.  Dari 100 kasus sebanyak 35 kasus mendapatkan pendosisan yang rasional dan 65 kasus pengobatan yang tidak rasional. Pendosisan rasional dengan efektivitas tercapai sebesar 85.7%  dan tidak tercapai 14.3%, pendosisan tidak rasional dengan efektivitas tercapai sebesar 83.1% dan tidak tercapai sebesar 16.9%.  Sedangkan efek samping tidak ditemukan pada kelompok rasional ataupun tidak rasional. Tidak terdapat hubungan yang signifikan antara rasionalitas dosis dengan efektivitas (p>0,05) maupun kejadian efek samping.
Pengaruh Konsentrasi Karagenan pada Sifat Fisika dan Kimia Sediaan Gummy Jamu Kunyit Asam
Authors: Rochmawati Nurul , Ermawati Dian Eka
Published: May 2021

Jamu kunyit asam merupakan minuman herbal khas Indonesia yang terbuat dari kunyit dan asam jawa. Industri jamu rumah tangga di Sleman Yogyakarta memproduksi jamu kunyit asam segar, namun belum dilakukan penetapan kadar zat aktif kurkuminoid. Konsumen jamu kunyit asam terbatas untuk wanita dan dewasa. Anak-anak jarang yang mau mengkonsumsi jamu, padahal kandungan kurkumin dalam kunyit juga dapat meningkatkan nafsu makan utamanya anak usia sekolah. Perlu inovasi untuk mengolah jamu segar menjadi produk yang lebih diminati, tahan lama namun tetap berkhasiat, salah satunya adalah sediaan gummy. Gummy dibuat dengan penambahan bahan pembentuk gel sehingga teksturnya kenyal. Karagenan merupakan gelling agent yang terbuat dari rumput laut dan aman untuk produk pangan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi karagenan terhadap sifat fisika dan kimia, serta untuk mengetahui konsentrasi optimum karagenan pada formulasi gummy jamu kunyit asam sesuai Standar Nasional Indonesia tentang kembang gula lunak. Penelitian ini merupakan penelitian eksperimental laboratorium dengan variasi konsentrasi karagenan (7.5%; 8.0%; 8.5%) serta jamu kunyit asam segar sebagai bahan utama. Pengujian sediaan meliputi organoleptik, pH, keseragaman bobot, kandungan air, waktu hancur dan uji penerimaan responden. Penetapan kadar kurkuminoid menggunakan metode spektrofotometri UV-VIS dan analisa statistik one way ANOVA. Hasil menunjukkan bahwa konsentrasi karagenan berpengaruh terhadap organoleptik, keseragaman bobot, kadar air, dan waktu hancur, namun tidak berpengaruh terhadap pH. Kadar kurkuminoid jamu segar 1.47% dan pada gummy 0.03% (b/b). Formula karagenan 8.0% merupakan formula optimum karena memenuhi syarat mutu sediaan gummy dan paling disukai oleh responden.
Molecular Bird Sexing of Tanimbar Cockatoos (Cacatua goffiniana) by Using Polymerase Chain Reaction Method
Authors: Hidayat Ratu Fresa Khoirotunnisa , Savitri Diana , Putri Irhamna , Nugrahani Warih Pulung , Haryanto Aris
Published: May 2021

This study aimed to determine the sex of Tanimbar Cockatoo (Cacatua goffiniana) birds by amplifying Chromodomain Helicase DNA-binding-1 (CHD-1) gene on Z and W sex chromosomes as well as to compare the quality of DNA extraction and PCR amplification products from samples derived from peripheral blood and plucked feathers. This work used five C. goffiniana birds which were collected from the Wildlife Rescue Center (WRC) in Pengasih, Kulon Progo, Yogyakarta. From each C. goffiniana, feather samples were collected by plucking feathers on the ventral wing and peripheral blood samples were taken by cutting their nails and collecting the blood into microhematocrit tubes containing heparin. The next stage was DNA extraction and DNA amplification on the CHD-1 gene using the PCR method by NP, P2, and MP primer pairs. Then, products of DNA extraction and PCR amplification were electrophoresed on 1.5% agarose gel and visualized under a UV light transilluminator with a wavelength of 260 nm. The visualization showed that samples from peripheral blood generated clearer DNA fragments compared to plucked feathers. Two of the five samples were male C. goffiniana and the other three samples were females. In the male Tanimbar Cockatoo was amplified a single DNA fragment of the Z sex chromosome in size of 300 bp, whereas in the female C. goffiniana was amplified double DNA fragments of Z and W sex chromosomes in size of 300 bp and 400 bp respectively. The DNA quality showed that the DNA quality from peripheral blood samples were better in quality than the DNA collected from plucked feather samples.
Dimensiones de la (in)gobernanza territorial en conflictos socioambientales. Un análisis desde la minería en México
Authors: Martínez Salvador Laura Elena , Martínez Salvador Carolina
Published: May 2021

Objetivo: analizar los conflictos socioambientales derivados de las actividades mineras en México para identificar los elementos de (in)gobernanza territorial que inciden en su ocurrencia, con la finalidad de contribuir a un mejor entendimiento de los factores que detonan dichos conflictos. Metodología: se llevó a cabo un análisis sistemático y exploratorio de las narrativas públicas de los conflictos a partir de cuatro dimensiones: asimetrías en la información; desarticulación y gestión de la estructura normativo-institucional; insostenibilidad del uso de los recursos territoriales; y desacuerdos en el acceso a los beneficios por el uso de los recursos). Resultados: las dimensiones más comunes de la (in)gobernanza son la insostenibilidad del uso de recursos y las desarticulaciones institucionales. Limitaciones: la generalización de los fenómenos sociales complejos (esto es, conflictos socioambientales) puede desdibujar los elementos particulares de un fenómeno social. Valor: esta sistematización propone un nuevo esquema analítico que integra la gobernanza como elemento definitorio en la génesis de conflictos socioambientales. Conclusiones: existe correlación entre ciertos momentos históricos que tienen una mayor incidencia de conflicto; la ruptura de cualquiera de las dimensiones más comunes parece elemento suficiente para detonar un conflicto social, aunque la mayoría de los conflictos presenta rupturas a lo largo de sus cuatro dimensiones.
Internacionalización de las plataformas públicas de streaming de América del Norte
Authors: Muñoz Larroa Argelia Erandi
Published: May 2021

El siguiente artículo estudia la internacionalización de las plataformas públicas de streaming de América del Norte como una oportunidad para contribuir a la diversidad cultural a nivel mundial. La expansión geográfica de las plataformas públicas depende de sus objetivos, costes operativos y de las condiciones legales del contenido. Este artículo identifica cinco modalidades de internacionalización de las plataformas de la región: 1) monetización, 2) conexión con la diáspora/migrantes, 3) difusión internacional, 4) internacionalización involuntaria y 5) el bloqueo de contenidos en el extranjero. Se encontró que: i) los mayores obstáculos a la internacionalización son el manejo de derechos y los costos de la infraestructura de distribución y promoción; ii) que las limitantes anteriores y las barreras idiomáticas hacen escasa la disponibilidad de las plataformas públicas de streaming entre los países de América del Norte; y iii) que la modalidad de difusión internacional, que deliberadamente busca dar a conocer la cultura propia a los extranjeros, es incipiente y queda al margen de políticas estatales.
Act of Phytochemical-Based Antioxidants in Neurodegenerative Disorders Utilizing Indian Medicinal Plants
Authors: MP Navya Raj , Singh Pooja G , BV Sushma
Published: May 2021

Neurodegenerative diseases are multifactorial nervous system deteriorating conditions that concern over 30 million aging populations worldwide. The effect of protein malfunction or defective trafficking is neurodegenerative disease, such as Alzheimer disease [AD], Parkinson’s disease [PD], Huntington's and Amyotrophic lateral sclerosis disorders. Furthermore, mitochondrial dysfunction, oxidative stress / age-linked environmental factors have also been involved. Prolonged use of synthetic medications could lead to adverse side effects for these illnesses. Henceforth herbal therapy attracts much attention rather than a pharmaceutical therapy is favoured. Indeed, several research studies have identified use of medicinal plants and their components for drug production, and recently more than 100 new medicines are now being established clinically. Accumulative data shows that nutraceuticals property is critical for cognition optimisation and risk mitigation. The study explores the role of phytochemical based antioxidants in cognitive and adverse signal transduction events, with a special focus on the Mediterranean diet [MeDi] comprising bioactive compounds like - xanthophyll carotenoids and omega-3 fatty acids. These phytochemical compounds are capable of improving cognition, considering their selective brain involvement and their specifically oxidative damage and inflammation. The objective of this study is to detail the molecular mechanisms of some Ayurvedic plants signal transduction and locations of operation. It is hoped that this review further helps to examine a new therapeutic recommendations and further research in clinical trials on the use of poly-herbal Ayurvedic medicine for the treatment and prevention of dementia. It is expected to increase the ease in the usage of Ayurveda-based knowledge base combined with combined scientific and high-performance screening strategies in the drug research and development campaign, while offering new practical guidelines for neurosurgical diseases linked to age.
[Ensaio] “Bom dia camaradas” e um retrato de uma (infância em) Angola
Authors: Franco Roberta Guimarães
Published: May 2021

Ensaio sobre Bom dia camaradas, de Ondjaki.
“Todos os nomes”, de José Saramago: um texto entre dobras
Authors: Paranhos Maria Cecília Rogers
Published: May 2021

Este texto se propõe desenvolver uma análise sobre a presença de traços do barroco no romance Todos os Nomes, de José Saramago. Para isso, serão utilizadas, sobretudo, reflexões de Gilles Deleuze, em sua obra A Dobra: Leibniz e o Barroco, em que, além da questão da dobra infinita e de seus respectivos desdobramentos, aborda-se a questão do movimento do indivíduo e da liberdade do ato voluntário, que conduzem ao ato acabado, bem como a questão do homem inacabado e da imutabilidade dos conceitos impostos pelo poder, características presentes no século do Barroco e também perceptíveis em nossa sociedade contemporânea. Por outro lado, o trabalho busca evidenciar a técnica narrativa do romance, relacionando-a ao tema da aventura cotidiana e do anti-herói moderno, como também à carnavalização da literatura, utilizando-se de alguns conceitos desenvolvidos por Mikhail Bakhtin.
Da musicalidade barroca em o “Manual dos inquisidores”
Authors: Andrade Mariana Neto Silva
Published: May 2021

O objetivo do presente trabalho é propor uma relação entre elementos de uma musicalidade própria do período barroco e sua aplicação em um texto literário contemporâneo; no caso, o romance O manual dos inquisidores, do escritor português António Lobo Antunes, publicado no ano de 1998. Explicitarei certos procedimentos artísticos manifestos na obra, tais como a repetição de palavras e frases, a organização textual e a presença da polifonia, enquanto traços marcantes de um legado cultural herdado do barroco, esse aqui entendido não como um movimento preso a um instante histórico, mas como um estado de espírito que pode ocorrer em outras épocas, a exemplo da contemporaneidade.
“... Dar esse salto do vivido para o escrito, isso é a poesia...”
Authors: Miguelote Carla
Published: May 2021

Entrevista a Gastão Cruz.
Os primeiros cultores da maneira italiana em Portugal
Authors: Franco Marcia Arruda
Published: May 2021

O presente artigo pretende examinar a relação entre poesia, sociedade e poder no século XVI, enfocando o patronato e a introdução do código poético italiano na poesia portuguesa, por meio dos sonetos dedicados ao príncipe Dom João por Sá de Miranda e do diálogo poético entre este e Dom Manuel de Portugal, os primeiros cultores da maneira italiana em Portugal.
Flashes de estética comparada: lendo imagens cabo-verdianas
Authors: Gomes Simone Caputo
Published: May 2021

O ensaio apresenta, na linha teórica da Estética Comparada, uma galeria de textos e telas cabo-verdianos a serem lidos na relação entre literatura e pintura, de modo a dar a ver como as óticas masculina e feminina recortam imagens de mulher e seus cotidianos. Os escritores Fátima Bettencourt, Manuel Lopes, Maria Margarida Mascarenhas, Oswaldo Osório, Vasco Martins, Vera Duarte dialogarão entre si e com os pintores Armando do Rosário, Kiki Lima, Misá, Sandro Brito, Tchalê Figueira e Tony Barbosa, a partir de visões diversificadas da situação social das mulheres em contexto cabo-verdiano, sob a inspiração ou contestação da Vênus canônica de Botticelli.
Uma ética da existência em “Arte de Música”, de Jorge de Sena
Authors: Macedo Sebastião Edson
Published: May 2021

Uma leitura da intervenção musical no discurso lírico de Jorge de Sena a partir do livro Arte de Música, apontando para o modo como uma ética seniana da existência é posta em discussão por conta das problemáticas desencadeadas pela incongruência entre o sistema de representação da música e da poesia.
[Excerto] Da última ficção de Teolinda Gersão, A cidade de Ulisses, 2011
Authors: Gersão Teolinda
Published: May 2021

Excerto de A cidade de Ulisses, de Teolinda Gersão.
"A nova poesia portuguesa", de Manuel de Freitas
Authors: Braga Duarte Drumond
Published: May 2021

Livro resenhado:FREITAS, Manuel de. A Nova Poesia Portuguesa. Lisboa: Poesia In­completa, 2010.
Representações da Mãe-África nas poesias moçambicana e afro-brasileira
Authors: Santos Donizeth
Published: May 2021

Através da análise dos poemas “Sangue negro”, da poeta moçambicana Noémia de Sousa, “Regressão” e “Elo”, do poeta afro-brasileiro Oliveira Silveira, o artigo mostra que a Mãe-África é representada na poesia moçambicana como a mãe negra biológica, a nação, e o continente africano, enquanto que na afro-brasileira, além de ser a progenitora da raça negra, o continente africano é também a terra prometida, o paraíso perdido.
"Candid camera?" (Da presença e usos do fotográfico em alguma poesia portuguesa contemporânea)
Authors: Pereira Paulo Alexandre
Published: May 2021

No presente artigo, examina-se a presença e funcionalidade do paradigma fotográfico em alguma poesia portuguesa contemporânea, procurando-se ilustrar a diversidade das suas incidências ideotemáticas e das estratégias de composição poética que com ele se conexionam.
Revisitações poéticas e pictóricas da Ilha de Moçambique
Authors: Secco Carmen Lucia Tindó
Published: May 2021

A reescrita de Moçambique com a pena da poesia e as tintas dos afetos. Paisagens: poesia, pintura e história. O entrecruzamento de povos, culturas e saberes no chão moçambicano de heranças múltiplas.
No corpo, na casa e na cidade: as moradas da ficção
Authors: Cruz Eduardo da
Published: May 2021

Livro resenhado:FIGUEIREDO, Monica. No corpo, na casa e na cidade: as moradas da ficção. Rio de Janeiro: Língua Geral, 2011.
Cyber Crime dalam Bentuk Phising Berdasarkan Undang-Undang Informasi dan Transaksi Elektronik
Authors: Gulo Ardi Saputra , Lasmadi Sahuri , Nawawi Khabib
Published: May 2021

ABSTRAK
Artikel ini membahas cyber crime dalam bentuk phising berdasarkan Undang-Undang tentang Informasi dan Transaksi Elektronik. Penelitian yang digunakan yakni penelitian hukum normatif. Hasil penelitian yang telah dilakukan menunjukan: 1) Pengaturan hukum terhadap cyber crime dalam bentuk phising berdasarkan Undang-Undang tentang Informasi dan Transaksi Elektronik tidak dapat dikenakan Pasal 35 jo Pasal 51 Ayat (1) dan Pasal 28 Ayat (1) jo Pasal 45A Ayat (1). 2) Kebijakan hukum terhadap cyber crime dalam bentuk phising berdasarkan Undang-Undang tentang Informasi dan Transaksi Elektronik adalah dilakukannya perubahan terhadap Undang-Undang tentang ITE dengan merumuskan konsep phising dan merubah isi Pasal 35.
ABSTRACT
This article discusses cyber crime in the form of phishing based on the Law on Electronic Information and Transactions. The research used is normative legal research. The results of the research that have been conducted demonstrated that: 1) Legal regulations on cyber crime in the form of phishing based on the Law on Electronic Information and Transactions cannot be subject to Article 35 in conjunction with Article 51 Paragraph (1) and Article 28 Paragraph (1) in conjunction with Article 45A Paragraph ( 1). 2) the criminal law policy against cyber crime in the form of phishing based on the Law on Electronic Information and Transactions is the amendment of the Law on ITE by formulating the concept of phishing and amending the contents of Article 35.
Penahanan Terhadap Anak Pelaku Tindak Pidana
Authors: Sitompul Ardiko , Haryadi Haryadi , Munandar Tri Imam
Published: May 2021

ABSTRAK
Penelitian ini bertujuan untuk memahami dan mengetahui faktor penahanan terhadap anak yang melakukan tindak pidana yang diancam pidana di bawah 7 (tujuh) tahun di Polres Tanjung Jabung Timur. Untuk memahami dan mengetahui kendala apa saja yang dihadapi dalam penahanan terhadap anak yang melakukan tindak pidana di bawah ancaman 7 (tujuh) tahun oleh Unit PPA Polres Tanjung Jabung Timur. Hasil Penelitian yang diperoleh dalam penelitian ini bahwa faktor yang menyebabkan penahanan terhadap pelaku anak yang dilakukan oleh Unit PPA Polres Tanjung Jabung adalah memberikan perlindungan terhadap ancaman serangan balasan dari korban, menghindari penghilangan barang bukti serta takut akan melarikan diri. Adapun kendala kendala yang dihadapi adalah terbatasnya sarana dan prasarana di Kabupaten Tanjung Jabung Timur sehingga tempat penahanan anak dilakukan di suatu ruangan khusus di Polres Tanjung Jabung Timur. Kurangnya dukungan dan kerjasama lembaga serta pelaksanaan ganti rugi yang tidak terlaksana sesuai kesepakatan.
ABSTRACT
This study aims to understand and determine the factors of detention of children who commit criminal acts which are punishable by under 7 (seven) years at the Tanjung Jabung Timur Police. To understand and find out what obstacles are faced in detention of children who commit criminal acts under the threat of 7 (seven) years by the PPA Unit of the Tanjung Jabung Timur Police. The results obtained in this study indicate that the factors that led to the detention of child perpetrators by the PPA Unit of the Tanjung Jabung Police were providing protection against the threat of retaliatory attacks from the victim, avoiding the loss of evidence and fear of running away. The obstacles faced are the limited facilities and infrastructure in East Tanjung Jabung Regency so that the place for detention of children is carried out in a special room at the Tanjung Jabung Timur Police. Lack of institutional support and cooperation and implementation of compensation that was not implemented according to the agreement.