bluuebunny/crossref_metadata_2025 huggingface dataset:
Managing Visitor and Patient Flow During the COVID-19 Pandemic: ExpectingU App
Authors: Ehrler Frederic , Trompier Remy , Merle Guerric , Andre Sebastien , Müller Florian , Blondon Katherine
Published: May 2021

Access to hospitals has been dramatically restricted during the COVID 19 pandemic. Indeed, due to the high risk of contamination by patients and by visitors, only essential visits and medical appointments have been authorized. Restricting hospital access to authorized visitors was an important logistic challenge. To deal with this challenge, our institution developed the ExpectingU app to facilitate patient authorization for medical appointments and for visitors to enter the hospital. This article analyzes different trends regarding medical appointments, visitors’ invitations, support staff hired and COVID hospitalizations to demonstrate how the ExpectingU system has helped the hospital to maintain accessibility to the hospital. Results shows that our system has allowed us to maintain the hospital open for medical appointments and visits without creating bottlenecks.
Evaluating Suitability of SNOMED CT in Structured Searches for COVID-19 Studies
Authors: Vorisek Carina Nina , Klopfenstein Sophie Anne Ines , Sass Julian , Lehne Moritz , Schmidt Carsten Oliver , Thun Sylvia
Published: May 2021

Studies investigating the suitability of SNOMED CT in COVID-19 datasets are still scarce. The purpose of this study was to evaluate the suitability of SNOMED CT for structured searches of COVID-19 studies, using the German Corona Consensus Dataset (GECCO) as example. Suitability of the international standard SNOMED CT was measured with the scoring system ISO/TS 21564, and intercoder reliability of two independent mapping specialists was evaluated. The resulting analysis showed that the majority of data items had either a complete or partial equivalent in SNOMED CT (complete equivalent: 141 items; partial equivalent: 63 items; no equivalent: 1 item). Intercoder reliability was moderate, possibly due to non-establishment of mapping rules and high percentage (74%) of different but similar concepts among the 86 non-equal chosen concepts. The study shows that SNOMED CT can be utilized for COVID-19 cohort browsing. However, further studies investigating mapping rules and further international terminologies are necessary.
Interpretable and Continuous Prediction of Acute Kidney Injury in the Intensive Care
Authors: Vagliano Iacopo , Lvova Oleksandra , Schut Martijn C.
Published: May 2021

Acute kidney injury (AKI) is a common and potentially life-threatening condition, which often occurs in the intensive care unit. We propose a machine learning model based on recurrent neural networks to continuously predict AKI. We internally validated its predictive performance, both in terms of discrimination and calibration, and assessed its interpretability. Our model achieved good discrimination (AUC 0.80-0.94). Such a continuous model can support clinicians to promptly recognize and treat AKI patients and may improve their outcomes.
Analysis of Frequency Bands of Uterine Electromyography Signals for the Detection of Preterm Birth
Authors: Selvaraju Vinothini , Karthick P.A. , Swaminathan Ramakrishnan
Published: May 2021

In this work, an attempt has been made to analyze the influence of the frequencies bands in uterine electromyography (uEMG) signals on the detection of preterm birth. The signals recorded from the women’s abdomen during pregnancy are considered in this study. The signals are subjected to preprocessing using digital bandpass Butterworth filter and decomposed into different frequency bands namely, 0.3-1.0 Hz (F1), 1.0-2.0 Hz (F2) and 2.0-3.0Hz (F3). Spectral features namely, peak magnitude, peak frequency, mean frequency and median frequency are extracted from the power spectrum. Classification models namely, k-nearest neighbor, support vector machine and random forest are employed to distinguish the term and preterm conditions. The results show that the features extracted from these frequency bands are able to differentiate term and preterm condition. Particularly, the frequency band F3 performs better than other frequency bands. The features associated with these frequencies along with random forest classification model achieves a maximum accuracy of 75.2%. Thus, these measures could be used to accurately detect the preterm birth well in advance.
From OpenEHR to FHIR and OMOP Data Model for Microbiology Findings
Authors: Rinaldi Eugenia , Thun Sylvia
Published: May 2021

HiGHmed is a German Consortium where eight University Hospitals have agreed to the cross-institutional data exchange through novel medical informatics solutions. The HiGHmed Use Case Infection Control group has modelled a set of infection-related data in the openEHR format. In order to establish interoperability with the other German Consortia belonging to the same national initiative, we mapped the openEHR information to the Fast Healthcare Interoperability Resources (FHIR) format recommended within the initiative. FHIR enables fast exchange of data thanks to the discrete and independent data elements into which information is organized. Furthermore, to explore the possibility of maximizing analysis capabilities for our data set, we subsequently mapped the FHIR elements to the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM). The OMOP data model is designed to support the conduct of research to identify and evaluate associations between interventions and outcomes caused by these interventions. Mapping across standard allows to exploit their peculiarities while establishing and/or maintaining interoperability. This article provides an overview of our experience in mapping infection control related data across three different standards openEHR, FHIR and OMOP CDM.
Identifying Core Outcome Sets in COVID-19 Clinical Trials Using ClinicalTrials.gov
Authors: Parvanova Irena , Finkelstein Joseph
Published: May 2021

Introduction of core outcome sets (COS) facilitates evidence synthesis, transparency in outcome reporting, and standardization in clinical research. However, development of COS may be a time consuming and expensive process. Publicly available repositories, such as ClinicalTrials.gov (CTG), provide access to a vast collection of clinical trial characteristics including primary and secondary outcomes, which can be analyzed using a comprehensive set of tools. With growing number of COVID-19 clinical trials, COS development may provide crucial means to standardize, aggregate, share, and analyze diverse research results in a harmonized way. This study was aimed at initial assessment of utility of CTG analytics for identifying COVID-19 COS. At the time of this study, January, 2021, we analyzed 120 ongoing NIH-funded COVID-19 clinical trials initiated in 2020 to inform COVID-19 COS development by evaluating and ranking clinical trial outcomes based on their structured representation in CTG. Using this approach, COS comprised of 25 major clinical outcomes has been identified with mortality, mental health status, and COVID-19 antibodies at the top of the list. We concluded that CTG analytics can be instrumental for COVID-19 COS development and that further analysis is warranted including broader number of international trials combined with more granular approach and ontology-driven pipelines for outcome extraction and curation.
Technically Representing Clinical Knowledge for Rehabilitation Care
Authors: Gand Kai , Böcking Lars , Kreiner Karl , Schlieter Hannes , Burwitz Martin , Gißke Carola , Philipp Patrick , Kropf Johannes
Published: May 2021

Providing a suitable rehabilitation after an acute episode or a chronic disease helps people to live independently and enhance their quality of life. However, the continuity of care is often interrupted in the transition from hospital to home. Virtual coaches (VCs) could help these patients to engage in personalized home rehabilitation programs. These coaching systems need also to be fed with procedural precepts in order to work as intended. This, in turn, relates both to properly represent the clinical knowledge (as the VC somehow replaces the formal caregivers that cannot be fully present) as well guide the patient correctly (in order to follow the medically desired procedures given the need for personalisation according to individual needs). Therefore, we outline our technical approach to deal with this. In particular, clinical pathways in terms of semi-formal procedure models in combination with machine learning components processing and powerful user interfaces providing these pathway information and feeding the VC are presented. The system is currently under testing in a participatory design phase called Living Lab. Thus, initial user feedback for further improvements is about to come.
Implementation of a Computerized Provider Order Entry System in a Pediatric Hospital in Canada
Authors: Liang Man Qing , Boudjellab Amélie , Kwon Hyukjin , Jouvet Philippe , Lebel Denis , Thibault Maxime , Motulsky Aude
Published: May 2021

The Centre Hospitalier Universitaire Sainte-Justine (Montreal, Canada) is a pediatric academic tertiary hospital that has begun the implementation of a commercial computerized provider order entry system (CPOE) in October 2019. The objectives of this paper are 1) to estimate the impact of the CPOE system on medication errors, and 2) to identify vulnerability issues related to the configuration of the CPOE system’s design. Using a pre-post implementation methodology measuring medication errors captured by clinical pharmacists revealed that the implementation of a CPOE has eliminated all prescription conformity (e.g., missing fields) and legibility errors. Pharmacists have continued to detect medication errors, especially inappropriate dosing instructions, and to intervene in similar clinical situations (medication reconciliation, deprescribing, adjusting orders). Additionally, the vulnerability analysis, based on typical clinical order test cases in an inpatient pediatric setting, highlighted the need to configure a clinical decision support system that can identify inappropriate dosing instructions for pediatric patients.
Renal Health: Providing Information and Technological Tools to Empower Patients to Live Better with Kidney Disease
Authors: da Silva Junior Geraldo Bezerra , de Oliveira Juliana Gomes Ramalho , de Araújo Erica Maria Rodrigues , Albuquerque Ana Carolina Rattacaso Marino de Mattos , Mota Fabio Augusto Xerex , de Freitas Filho Ronaldo Almeida , de Vasconcelos Filho José Eurico , Rodrigues Maria Andréia Formico
Published: May 2021

Chronic kidney disease (CKD) is a growing Public Health problem. Recent evidence points that low education and poor socio-economic conditions are associated with higher risk of developing CKD and progressing to dialysis or transplantation need. Hence patient empowerment through health education and qualification with technological tools that allows better treatment adherence may play an important role in the achievement of optimal clinical outcomes. The Renal Health is a multidisciplinary project created at the University of Fortaleza, northeast Brazil, in 2015, aiming to create novel educational material and technological tools for people with CKD, in different treatment modalities, including dialysis and transplant. The products developed so far in the project include an application for smartphones aiming to help patients in dialysis and transplant in their treatments, including schedule for medications, with alarms, water ingestion control, laboratory tests results, and medical appointments’ agenda, besides all information regarding CKD. The other tools include a medication box, an insole for weight control (both are in the prototype phase), connection with smartbands (for vital signs monitoring) and multimedia educational tools, including a profile in the Instagram and a channel in YouTube. Since the first release of the application in the virtual stores, there were more than 1,000 downloads, predominantly in Brazil, although the app is also available in English and Spanish. All these tools represent innovative ways of patient empowerment and may be increasingly present in daily life. Further studies are required to assess the impact of these tools in patients’ outcomes, including CKD progression and mortality.
Development of a Role Model for the Use of Smart Home Based Data in Medical Care
Authors: Richter Isabel , Mielke Corinna , Haux Reinhold
Published: May 2021

Smart home systems create new opportunities for patient care. In this paper, a role model is created for the different groups of people involved in the care process of an occupant. Based on a systematic literature review seven roles were identified. A second literature review deals with the topic Feedback of Smart Home Systems. Combining both reviews visualization proposals were created and are presented for two of the roles. The role model is adapted to German health system but could be transformed for different countries. To confirm the results an evaluation of role model and visualization proposal should be done in collaboration with possible users of smart homes.
Remote Interviews and Visual Timelines with Patients: Lessons Learned
Authors: Valkonen Paula , Karisalmi Nina , Kaipio Johanna , Kujala Sari
Published: May 2021

This article aims to support the design of remote user studies in the healthcare and well-being field. We introduce lessons learned from conducting remote interviews and using visual timelines as pretasks involving patients from two eHealth projects. Based on our experience, we conclude that remote interviews and visual timelines can provide rich data about user needs. However, careful planning is required. Building trust, rapport, confidentiality, and privacy requires extra effort from the researcher in studies involving sensitive topics. In this paper, we present a list of practical tips for planning qualitative health-related user studies.
Can the European EHR Exchange Format Support Shared Decision Making and Citizen-Driven Health Science?
Authors: Bonacina Stefano , Koch Sabine , Meneses Isabel , Chronaki Catherine
Published: May 2021

The European Commission published in 2019 the Recommendation on the European Electronic Health Record exchange format (EHRxF) to support citizens and healthcare providers in securely accessing and sharing EHRs. The European EHRxF is expected to contribute to the digital transformation of health and care in the digital single market empowering citizens and building a healthier society. This paper presents areas of work that need to be resolved for the European EHRxF to advance shared decision-making for patients and citizen-centered science.
Evaluation Methods Used to Assess mHealth Applications for Cardiovascular Disease: First Results of a Scoping Review
Authors: Holl Felix , Kircher Jennifer , Swoboda Walter
Published: May 2021

Potential benefits of mHealth applications are large for chronic diseases. To get an overview of how these applications are being evaluated, a scoping review is being conducted. First results show that single factors are most commonly assessed. The results of clinical outcome measures are the most common. Economic factors are the least common. A uniform framework that specifies different factors and metrics for the evaluation is not apparent.
Visualising Patterns Associated with Adverse Drug Reactions in French Forums
Authors: Allam Nour , Audeh Bissan , Jaulent Marie-Christine , Bousquet Cedric
Published: May 2021

As social media are an interesting source of information for pharmacovigilance, we implemented a novel visualisation method for pharmacovigilance specialists applied to French discussion forums. A word embedding model was trained on posts to facilitate the identification of patterns associated with adverse drug reactions.
Brimonidine as an additional treatment for moderate glaucoma
Authors:   N.P. Bekhtereva Institute of the Human Brain, Saint Petersburg, Russian Federation, Gazizova I.R. , Korelina V.E. ,   LLC “American Medical Clinic”, Saint Petersburg, Russian Federation,   I.I. Mechnikov North-Western State Medical University, Saint Petersburg, Russian Federation
Published: May 2021

Aim: to assess the utility of brimonidine 0.2% as an additional IOP-lowering treatment for moderate glaucoma. Patients and Methods: 99 patients (121 eyes) aged 62–73 years with moderate glaucoma were enrolled. All patients were divided into four groups based on IOP-lowering medications. In group 1, prostaglandin analogues (latanoprost) and beta blockers (timolol) were prescribed. In group 2, carbonic anhydrase inhibitors (dorzolamide) and beta blockers (timolol) were prescribed. In group 3, brimonidine 0.2% was added to prostaglandin analogues and beta blockers. In group 4, brimonidine 0.2% was added to carbonic anhydrase inhibitors and beta blockers. All patients underwent IOP measurements and static automated perimetry (SAP) at baseline and after 6 and 12 months. Results: additional treatment (brimonidine) gradually reduced IOP levels in groups 3 and 4, while in groups 1 and 2 IOP levels were stable. In group 1, mean deviation (MD) increased from -10.7±4.5dB to -10.8±3.8 dB after 6 months but reduced to -10.5±3.4 dB after 12 months. In group 2, MD increased from -11.7±5.1 dB to -12.0±3.2 dB after 6 months and -12.5±2.9 dB after 12 months. In group 3, MD reduced from -13.5±4.1 dB to -12.9±3.6 dB after 6 months and -12.7±3.0 dB after 12 months. In group 4, MD reduced from -13.9±4.6 dB to -13.0±4.1 dB after 6 months and increased to -13.1±3.5 dB after 12 months. Pattern standard deviation (PSD) was stable in all four groups. Conclusion: brimonidine as an additional treatment for moderate and advanced glaucoma results in stable IOP reduction. Combined therapy which includes brimonidine preserves visual functions even in moderate-to-advanced glaucoma. The neuroprotective effect of brimonidine is illustrated by SAP. This medication is well tolerated. Keywords: glaucoma, IOP, visual field, perimetry, tonometry, neuroprotection. For citation: Gazizova I.R., Korelina V.E. Brimonidine as an additional treatment for moderate glaucoma. Russian Journal of Clinical Ophthalmology. 2021;21(2):69–71. DOI: 10.32364/2311-7729-2021-21-2-69-71.
Viagens ao Sudoeste do Rio Grande do Sul
Authors: Rambo Balduíno
Published: May 2021

Os textos oferecidos em primeira mão compõem um retrato de parte significativa do Sudoeste do Rio Grande do Sul de há mais de sete décadas.
Effects of Campaign-Based Soil and Water Conservation Practice on Soil Properties: The Case of Workamba Watershed, Debark District, North Ethiopia
Authors:   Department of Natural Resource Management, Debark University, College of Agriculture and Environmental Science (DKU CAES), P.O Box 90, Debark, Ethiopia, Bogale Muluneh , Wondie Getnet ,   1Department of Natural Resource Management, Debark University, College of Agriculture and Environmental Science (DKU CAES), P.O Box 90, Debark, Ethiopia, Shafi Abdrahman ,   Department of Natural Resource Management, Wolkite University, College of Agriculture and Natural Resource Management, P.O Box 70, Wolkite, Ethiopia
Published: May 2021

Land degradation is a serious environmental problem in Ethiopia. To address the problem, soil and water conservation practices were implemented through campaign. This study was conducted at Workamba watershed Debark district, North Ethiopia to assess the effect of campaign soil and water conservation (SWC) practice on selected soil properties. Composite soil samples from 1.5 meters above the soil bunds, at the center and 1.5 meters below the soil bunds between the two consecutive structures were collected. The soil samples were analyzed following standard laboratory procedures. Results showed bulk density (BD), electrical conductivity (EC), calcium (Ca2+), and sodium (Na+) were not significantly affected by slope gradient and terrace position and their interaction. But pH was significantly influenced by the interaction effect. Cation exchange capacity (CEC), exchangeable potassium (K+), and clay content were significantly changed with both slope gradient and terrace position. Whereas, total nitrogen (TN), available phosphorus (Av-P), and magnesium (Mg2+), and soil organic carbon (SOC) were significantly affected with terrace position and slope gradient, respectively. Because of the conservation barrier, most soil properties were better at the bottom terrace position and gentle slope gradient.
Az al-Káida céljai, szervezete és működése, módszerei és eljárásai a Nyugat ellen 1989 és 2015 között
Authors: Kovács Márk Károly
Published: May 2021

A jelen tanulmány az al-Káida rövid kialakulását és Oszáma bin Láden által felállított célok elérésére tett kísérleteket  mutatja be. A szervezet létrejötte óta számos strukturális változáson ment keresztül, amiből egy globális mozgalom is kialakult. A mozgalommal párhuzamosan az al-Káida  magszervezete is folytatta működését, bár hatékonysága jelentősen csökkent az Amerikai Egyesült Államok és  szövetségeseinek terrorizmus elleni harca miatt. Az al-Káida-tagok által használt vagy az általa inspirált személyek a Nyugat elleni műveleteik során főként a robbantást és  öngyilkos merényleteket mint módszert alkalmazták. Fegyveres támadásokat is végrehajtottak, alkalmaztak, de  csak sérelmek megtorlására és nem általánosságban, véletlen kiválasztott célpontok ellen – ezért nem voltak jellemzők a szervezetre.
Intergenerational Education to Enhance Sustainable Community Development
Authors: Ličen Nives , Šindić Aleksandra , Lepičnik Vodopivec Jurka , Kožar Rosulnik Klara
Published: May 2021

The article outlines the emergent cooperation between generations in the local environment. The aim of the research was to identify the key characteristics of learning ecologies that may be used to promote new practices. The theoretical framework was constructed through the concepts of learning ecology, community education, and postformal education. A qualitative research approach was used. Data was collected by means of 10 individual and one focus group interviews. The research revealed that the networks of different actors in the local community are effective approaches for developing intergenerational practices. It is important to connect different types of knowledge (intangible cultural heritage, local knowledge and scientific knowledge, social and emotional knowledge), skills and values, as well as different groups and organizations in the local environment to act and learn together.
Respon Pertumbuhan dan Produksi Tanaman Jagung Manis (Zea mays saccharata Sturt) Akibat Pemberian Bio Urine dan Pengaturan Jarak Tanam
Authors: Ramli Nursayuti
Published: May 2021

Respon Pertumbuhan dan Produksi Tanaman Jagung Manis  (Zea mays saccharata Sturt) Akibat Pemberian Bio Urine dan Pengaturan Jarak Tanam

 

Nursayuti1

Dosen Fakultas Pertanian Program studi Agroteknologi Universitas Almuslim Matang glumpang Dua Bireuen

Email: nursayuti1979@gmail.com

 

Abstrak

 

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian Bio Urine dan jarak tanam  terhadap pertumbuhan dan produksi tanaman jagung manis. Penelitian  ini  dilaksanakan  di  Desa Meunasah Cut Kecamatan Peudada Kabupaten Bireuen yang dimulai dari bulan Mei sampai dengan bulan Agustus 2019. Rancangan yang dilakukan dalam penelitian ini adalah Rancangan Acak Kelompok (RAK) faktorial dengan dua faktor perlakuan yang diteliti. Faktor I : Bio Urine (B) terdiri dari 3 taraf perlakuan yaitu : B0 = Tanpa pemberian (kontrol), B1 = Bio urine 60 ml/ L air, B2 = Bio urine 100 ml/ L air. Faktor II : Jarak Tanam (J) terdiri dari 3 taraf perlakuan yaitu : J0 = 70 cm x 30 cm (kontrol), J1 = 50 cm x 50 cm dan J2 = 50 cm x 40 cm. Pengamatan yang diamati dalam penelitian ini meliputi tinggi tanaman, diameter batang, jumlah daun, berat tongkol berkelobot, berat tongkol tanpa kelobot, panjang tongkol dan berat 1000 butir. 

Hasil penelitian menunjukkan bahwa pemberian Bio Urine berpengaruh sangat nyata terhadap tinggi tanaman umur 15 dan 45 HST, diameter batang umur 15 dan 30 HST, jumlah daun 30 dan 45 HST, berat tongkol berkelobot, berat tongkol tanpa kelobot, panjang tongkol dan jumlah baris per tongkol tanaman jagung manis. Perlakuan terbaik dijumpai pada konsentrasi Bio Urine 60 dan 100 ml/l air (B1 dan B2). Pelakuan jarak tanam berpengaruh sangat nyata terhadap pertumbuhan tinggi tanaman umur 15 HST, diameter batang umur 45 HST, jumlah daun 15, 30 dan 45 HST dan berat tongkol berkelobot tanaman jagung manis. Perlakuan terbaik dijumpai pada jarak tanam  50 cm x 40 cm (J2). Kombinasi perlakuan Bio Urine dan jarak tanam berpengaruh yang sangat nyata terhadap pertumbuhan tinggi tanaman umur 15 HST, diameter batang 15 HST, jumlah daun 15, 30 dan 45 HST, panjang tongkol, jumlah baris per tongkol dan berat 1000 butir tanaman jagung manis, akan tetapi tidak berpengaruh  yata terhadap berat tongkol berkelobot dan berat tongkol tanpa kelobot. Perlakuan terbaik dijumpai pada kombinasi perlakuan Bio Urine konsentrasi 100 ml/l air dan jarak tanam  50 cm x 40 cm (B2 J2)

 

Kata Kunci : Bio Urine, Jarak Tanam, Jagung Manis
EFEKTIFITAS PEMBERIAN BAHAN ORGANIK DAN PUPUK KANDANG TERHADAP PERTUMBUHAN DAN PRODUKSI JAGUNG MANIS (Zea mays saccharataSturt.) PADA TANAH INCEPTISOL
Authors: Iqbal Iqbal
Published: May 2021

Penelitian ini bertujuan untuk mengetahui efektifitas pemberian bahan organik dan  pupuk kandang terhadap pertumbuhan jagung manis (Zea mays saccarat Sturt)  pada tanah Inceptisol. Penelitian ini dilakasanakan di Desa Meurandeh Dayah, Kecamatan Langsa Lama, Kota Langsa, pada bulan Juli sampai September 2020. Penelitian ini menggunakan Rancang Acak Lengkap (RAK) pola fakorial yang terdiri dari 2 faktor, yaitu: faktor jenis bahan organik (B) yang terdiri dari  3 taraf.  B0= (Kontrol) B1= Ampas Jerami Padi dan B2= (AmpasTebu) dan faktor pupuk kandang (K) yang terdiri darii taraf  K0= (Kontrol),  K1= (Pupuk Kandang Sapi) K2= (Pupuk Kandang Kambing) dan K3= (Pupuk Kandang Ayam). Parameter yang diamati antara lain: tinggi tanaman dan diameter batang umur 15, 30 dan 45 HST, panjang tongkol, berat tongkol berklobot dan tanpa klobot pertanaman dan produksi perhektar. Hasil terbaik diperoleh pada perlakuan pemberian bahan organik ampas tebu (B2). Hasil pengamatan  terbaik diperoleh pada interaksi perlakuan pemberian bahan organik ampas tebu (B2) dan kandang ayam (K3).
Türkiye su ürünleri sektöründe mevcut durum, sorunlar ve çözüm önerileri
Authors: ŞAKIMA İsmail , ÇEVRİMLİ Mustafa Bahadır
Published: May 2021

Dünya nüfusundaki hızlı artış, yükselen yaşam standartları ve tüketim alışkanlıklarındaki değişiklikler, balık ve diğer balıkçılık ve su ürünleri yetiştiriciliği ürünlerine olan talebi her geçen gün artırmaktadır. Türkiye ve dünyadaki balıkçılık ve su ürünleri sektörü, hayvancılık sektörünün sürekli gelişen, ülkelere ihracat geliri ve gıda güvenliğine katkı sağlayan önemli bir alt üretim dalıdır. Bu çalışmada su alanı bakımından zengin coğrafi yapıya sahip olan Türkiye’nin balıkçılık ve su ürünleri sektörünün mevcut durumu değerlendirilmiş ve dünyadaki mevcut durumla karşılaştırılmıştır. Türkiye'nin balıkçılık ve su ürünleri yetiştiriciliği sektöründe yükselen ivmeyi sürdürerek dış ticarette rekabet gücünün artırılması gerekmektedir, Bunun için üretim planlaması, katma değerli ürünlerin üretilmesi, balık stoklarının sürdürülebilir olarak yönetilmesi ve verimlilik artışı hedeflenmelidir. Türkiye, araştırma ve geliştirme faaliyetlerini destekleyerek, dışa bağımlılığın en önemli unsuru olan denizaşırı balık yemi kaynaklarına olan bağımlılığı azaltacaktır. Sektör gelişimi açısından gündemde tutulması gereken diğer konular arasında uluslararası standartları karşılayan yeni işleme tesislerinin kurulması ve mevcut tesislerde maksimum verim sağlanması yer almaktadır.
The Effect of Facebook Addiction on the Identity Crisis of the University Student
Authors: Boumediene Senouci , Djellouli Zineb  , M. Yoserizal Saragih
Published: May 2021

The study aimed to reveal the impact of Facebook addiction on the identity crisis of the university student, and to know the relationship between internet addiction and identity crisis in its various dimensions (concept of self, self-esteem, direction towards the other, school and professional tendencies) of the university student. The study sample consists of (91) university students, and to achieve the objectives of the study two research tools have been used: the first is internet addiction scale developed by 'Ahmed' (2007), and the second is the identity crisis scale developed by the following researchers: 'Shand, Mohammed Samira and Shaheen, Iman Fawzi and Private, Hadi Hassan Raafat' (2015). To reveal the identity crisis and after collecting and processing information statistically using  the Statistical Package for Social Sciences (SPSS) and R program, the researchers reached the following conclusions:

The coefficient of correlation between the concept of self and Facebook addiction is statistically significant.

The coefficient of self-esteem and internet addiction is statistically non-significant.

The correlation coefficient between the other direction and internet addiction is statistically non- significant.

The correlation coefficient between school and occupational tendencies and Internet addiction is statistically significant.

Internet addiction affects the concept of self.

Internet addiction does not affect self-esteem.

Internet addiction does not affect the trend towards the other.

Internet addiction does not affect school and professional tendencies.
The Social Pedagogical Discourse of Modernity. The Politics of Human Rights and International Social Work
Authors: Wevelsiep Christian
Published: May 2021

The basic thesis of this paper is that the helping professions have an indispensable task: to reflect the constitution of society in the context of the perception of the other. This discourse of social pedagogy addresses the conditions under which we encounter each other and under which we recognize each other. It is to be asked to what extent this discourse of social pedagogy could contribute to open the horizons of the common, which have been closed by all conceivable forms of violence. The background of the discourse, mentioned here, is close to the social philosophical discourse of modernity. It reflects the form of modernity in all its moral, social and political dimensions. The social-philosophical reference to the present is accompanied by the indispensable critique of power. It designates stages of reflection of that critique that make possible a theory of society. It thus forms, which is to be shown as aa result, the categorical framework of an analysis that enables a view of the structures of existing power relations. It thematizes the essential approaches to the practical overcoming of these phenomena. For this purpose, it will be reflected by way of introduction which theoretical reference the mentioned discourse has and how it is to be understood in comparison to other discourses - thus, it is first about the connections from social philosophy to social pedagogy (2). Within this framework, it will then be shown that the helping professions have an internal reference to the world, which is of eminent importance for the self-description of the discourse (3). How the language of human rights can be translated into transcultural perspectives of action is a complex question that is answered here from a fundamental anthropological perspective (4).
The Same of Beauty of Vision: The Common Research of Photography and Painting
Authors: Hu Xiaobing , Fang Tong
Published: May 2021

Photography is the use of view frames to leave a moment of beauty; art is to show the beauty of things on the canvas. Both reflect beauty, bearing the artistic beauty of things, they have a very close relationship. Photography and painting need to be carefully observed from the object of expression, and then from the composition, color, lighting and other aspects to express the main body. This is not only a skill, but also requires the author to have his own unique ideas, thinking and unique vision, so as to use the author's "window of the mind" to find something special to resonate with the viewer.
INOVASI SISTEM INFORMASI APLIKASI MOBILE PAJAK DAERAH (SAMPADE) DALAM MENINGKATKAN PELAYANAN PUBLIK
Authors: Larasati Dewi Citra
Published: May 2021

Sistem Informasi Aplikasi Mobile Pajak Daerah (SAMPADE) Kota Malang merupakan sebuah inovasi yang dilakukan oleh Badan Pelayanan Pajak Daerah (BP2D) Kota Malang berupa aplikasi berbasis teknologi informasi yang diharapkan memudahkan masyarakat atau wajib pajak dalam memenuhi pelayanan perpajakannya. Metode penelitian ini menggunakan metode penelitian kualitatif. Berdasarkan hasil penelitian terhadap pelaksanaan Inovasi Badan Pelayanan Pajak Daerah (BP2D) Kota Malang Melalui Sistem Informasi Aplikasi Mobile Pajak Daerah (SAMPADE) Dalam Meningkatkan Pelayanan Publik terdapat 5 indikator jenis inovasi yaitu inovasi proses, inovasi, metode, inovasi struktur organisasi, inovasi dalam hubungan, dan inovasi produk. Faktor pendukung dalam pelaksanaan dalam inovasi Sistem Informasi Aplikasi Mobile Pajak Daerah (SAMPADE) adalah disambut dengan baik oleh sebagian wajib pajak dan kerja sama dengan pihak luar yaitu CV. Sinergi. Serta dilengkapi dengan sarana dan prasana yang membantu dalam pelaksanaan sosialisasi kepada wajib pajak yaitu berupa 2 (dua) buah mobil khusus. Sedangkan untuk faktor penghambat dalam pelaksanaannya adalah inovasi Sistem Informasi Aplikasi Mobile Pajak Daerah (SAMPADE) ini terkadang terkena hacking dan server nya yang terkadang down dan masih rumit dalam penggunaannya. Serta masih ada beberapa wajib pajak yang belum mengerti menggunakan aplikasi ini dan beberapa wajib pajak juga belum mengerti IT dan lebih suka melakukan pelayanan perpajakan nya secara manual dengan pergi ke kantor Badan Pelayanan Pajak Daerah (BP2D) Kota Malang.
PARTISIPASI MASYARAKAT DALAM MENDUKUNG STRATEGI PELAYANAN DINAS PERPUSTAKAAN DAN KEARSIPAN KOTA BATU UNTUK MENINGKATKAN BUDAYA LITERASI PADA MASYARAKAT
Authors: Larasati Dewi Citra , Nahak Yovita Bano
Published: May 2021

Abstract. This study aims to determine how community participation in supporting the service strategy of the library and archival services in Batu City. Therefore, this study uses data obtained through words, written sources, photos through a qualitative method approach. Triangulation techniques are used as data collection techniques as well as data validity. The results of this study indicate that the community plays an active role in implementing the service strategy of the Batu City Library and Archives Service through mobile libraries, providing services at Taman Bacaan and cooperating with several communities in the Batu City community. Meanwhile, the supporting factors for the service strategy participation were shown enthusiastically from the employees and adequate service infrastructure. Meanwhile, the inhibiting factors faced are lack of human resources, delays in services and lack of awareness of the community itself about the importance of reading.Keyword : community participation, strategy, library servece managementAbstrak. Penelitian ini bertujuan untuk mengetahui bagaimana partisipasi masyarakat dalam mendukung strategi pelayanan dinas perpustakaan dan kearsipan Kota Batu. Oleh karena itu, penelitian ini menggunakan data yang diperoleh melalui kata-kata, sumber tertulis, foto melalui pendekatan metode kualitatif.  Triangulasi teknik digunakan sebagai teknik pengumpulan data serta keabsahan data. Hasil penelitian ini menunjukkan bahwa masyarakat berperan aktif dalam melaksanakan strategi pelayanan Dinas Perpustakaan dan Kearsipan Kota Batu melalui perpustakaan keliling, mengadakan layanan di Taman Bacaan dan bekerja sama dengan beberapa komunitas yang ada di masyarakat Kota Batu. Sedangkan untuk faktor pendukung partisipasi strategi pelayanan terlihat  dengan antusias dari pegawai dan sarana prasarana pelayanan yang memadai. Sedangkan untuk faktor yang menghambat yang dihadapi adalah kurangnya sumber daya manusia, keterlambatan pelayanan dan kurangnya kesadaran dari masyarakat itu sendiri akan pentingnya membaca.Kata Kunci: partisipasi masyarakat, strategi, manajemen pelayanan perpustakaan
The Spanish Translation of Hugh Blair's Lectures: An Early Anglo-Hispanic Canon
Authors: Arronte María Eugenia Perojo
Published: May 2021

The Spanish translation of Hugh Blair's Lectures on Rhetoric and Belles Lettres (1783) at the turn of the nineteenth century was one of the most remarkable literary events of the period in Spain. It appeared at a crucial time of shifting cultural paradigms and provoked an intense debate on some literary issues that were key in the transition to a new Romantic aesthetics, by introducing a view of the creative process based on pre-Romantic versions of the concepts of genius, the imagination and the sublime. But in its adaptation to the Spanish context Blair's work underwent a singular nationalization process. It also helped disseminate an Anglo-Hispanic canon that advanced the shift from French cultural dominance to an increasing Anglophilia that became noticeable in many Spanish authors and critics in subsequent decades. Thanks to the official adoption of the Lecciones as a rhetorical and literary handbook in schools and universities in the first half of the nineteenth century, the pre-Romantic canon established through Blair's work may have even contributed to the consolidation of literary eclecticism in Spain.
Transcarotid Access Versus Transfemoral Access for Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis
Authors: Lu Henri , Monney Pierre , Hullin Roger , Fournier Stephane , Roguelov Christian , Eeckhout Eric , Rubimbura Vladimir , Faroux Laurent , Barrier Adelin , Muller Olivier , Kirsch Matthias
Published: May 2021

Background: The transfemoral (TF) route is the gold-standard access for transcatheter aortic valve replacement (TAVR). In 10–15% of patients, alternative accesses are needed, such as the transcarotid (TC) access. We performed a meta-analysis to compare 30-day mortality and complications between TC-TAVR and TF-TAVR.

Methods: We searched PubMed/MEDLINE and EMBASE from inception to January 2021 to identify articles comparing TC-TAVR and TF-TAVR. Patients' baseline characteristics, procedural outcomes, and clinical 30-day outcomes were extracted.

Results: We identified 9 studies, among which 2 used propensity-score matching, including 1,374 TC patients and 3,706 TF patients. TC-TAVR was associated with significantly higher EuroSCORE II and Logistic EuroSCORE values (respectively 8.0 ± 6.7 vs. 6.3 ± 5.4, p = 0.002 and 20.8 ± 14.2% vs. 20.0 ± 13.4%, p = 0.04), a higher prevalence of peripheral artery disease (52.6 vs. 32.8%, p = 0.001), previous cardiac surgery (26.3 vs. 22.4%, p = 0.008) and coronary artery disease (64.6 vs. 60.5%, p = 0.020). The pooled results found TC-TAVR to be associated with a significantly higher 30-day mortality risk (RR, 1.41, 95% CI, 1.02–1.96, p = 0.040), and a lower rate of 30-day major vascular complications (RR, 0.48, 95% CI, 0.25–0.92, p = 0.030). No significant difference was found regarding permanent pacemaker implantation, major bleeding and acute kidney injury. A subgroup analysis of the two propensity-score matched studies found a statistically increased risk of 30-day neurovascular complications (RR, 1.61, 95% CI, 1.02–2.55, p = 0.040).

Conclusion: Compared with TF-TAVR, TC-TAVR was associated with an increased risk of 30-day mortality, likely related to a higher surgical risk and comorbidity burden, and with an increased risk of 30-day neurovascular complications. Careful preprocedural patient selection and close periprocedural neurological monitoring are paramount.
Pyrethroids Toxicity to Male Reproductive System and Offspring as a Function of Oxidative Stress Induction: Rodent Studies
Authors: Zhang Xu , Zhang Tongtong , Ren Xiaohan , Chen Xinglin , Wang ShangQian , Qin Chao
Published: May 2021

Pyrethroids may be related to male reproductive system damage. However, the results of many previous studies are contradictory and uncertain. Therefore, a systematic review and a meta-analysis were performed to assess the relationship between pyrethroid exposure and male reproductive system damage. A total of 72 articles were identified, among which 57 were selected for meta-analysis, and 15 were selected for qualitative analysis. Pyrethroid exposure affected sperm count (SMD= -2.0424; 95% CI, -2.4699 to -1.6149), sperm motility (SMD=-3.606; 95% CI, -4.5172 to -2.6948), sperm morphology (SMD=2.686; 95% CI, 1.9744 to 3.3976), testis weight (SMD=-1.1591; 95% CI, -1.6145 to -0.7038), epididymal weight (SMD=-1.1576; 95% CI, -1.7455 to -0.5697), and serum testosterone level (SMD=-1.9194; 95% CI, -2.4589 to -1.3798) in the studies of rats. We found that gestational and lactational exposure to pyrethroids can reduce sperm count (SMD=1.8469; 95% CI, -2.9010 to -0.7927), sperm motility (SMD=-2.7151; 95% CI, -3.9574 to -1.4728), testis weight (SMD=-1.4361; 95% CI, -1.8873 to -0.9848), and epididymal weight (SMD=-0.6639; 95% CI, -0.9544 to -0.3733) of F1 offspring. Exposure to pyrethroids can increase malondialdehyde (SMD=3.3451; 95% CI 1.9914 to 4.6988) oxide in testes and can reduce the activities of glutathione (SMD=-2.075; 95% CI -3.0651 to -1.0848), superoxide dismutase (SMD=-2.4856; 95% CI -3.9612 to -1.0100), and catalase (SMD=-2.7564; 95% CI -3.9788 to -1.5340). Pyrethroid exposure and oxidative stress could damage male sperm quality. Gestational and lactational pyrethroid exposure affects the reproductive system of F1 offspring.
The Insulin Response to Oral Glucose in GIP and GLP-1 Receptor Knockout Mice: Review of the Literature and Stepwise Glucose Dose Response Studies in Female Mice
Authors: Ahrén Bo , Yamada Yuichiro , Seino Yutaka
Published: May 2021

A key factor for the insulin response to oral glucose is the pro-glucagon derived incretin hormone glucagon-like peptide-1 (GLP-1), together with the companion incretin hormone, glucose-dependent insulinotropic polypeptide (GIP). Studies in GIP and GLP-1 receptor knockout (KO) mice have been undertaken in several studies to examine this role of the incretin hormones. In the present study, we reviewed the literature on glucose and insulin responses to oral glucose in these mice. We found six publications with such studies reporting results of thirteen separate study arms. The results were not straightforward, since glucose intolerance in GIP or GLP-1 receptor KO mice were reported only in eight of the arms, whereas normal glucose tolerance was reported in five arms. A general potential weakness of the published study is that each of them have examined effects of only one single dose of glucose. In a previous study in mice with genetic deletion of both GLP-1 and GIP receptors we showed that these mice have impaired insulin response to oral glucose after large but not small glucose loads, suggesting that the relevance of the incretin hormones may be dependent on the glucose load. To further test this hypothesis, we have now performed a stepwise glucose administration through a gastric tube (from zero to 125mg) in model experiments in anesthetized female wildtype, GLP-1 receptor KO and GIP receptor KO mice. We show that GIP receptor KO mice exhibit glucose intolerance in the presence of impaired insulin response after 100 and 125 mg glucose, but not after lower doses of glucose. In contrast, GLP-1 receptor KO mice have normal glucose tolerance after all glucose loads, in the presence of a compensatory increase in the insulin response. Therefore, based on these results and the literature survey, we suggest that GIP and GLP-1 receptor KO mice retain normal glucose tolerance after oral glucose, except after large glucose loads in GIP receptor KO mice, and we also show an adaptive mechanism in GLP-1 receptor KO mice, which needs to be further examined.
MET and FASN as Prognostic Biomarkers of Triple Negative Breast Cancer: A Systematic Evidence Landscape of Clinical Study
Authors: Jiang Weihua , Xing Xiao-Liang , Zhang Chenguang , Yi Lina , Xu Wenting , Ou Jianghua , Zhu Ning
Published: May 2021

Background

To know the expression of Mesenchymal–Epithelial Transition factor (MET) and Fatty Acid Synthase (FASN) in Triple Negative Breast Cancer (TNBC) patients, as well as its relationship with clinical pathological characteristic and prognosis.

Methods

we used immunohistochemistry staining to detect the expression of MET and FASN for those 218 TNBC patients, and analyze their relationship with the clinical pathological characteristic and prognosis.

Results

130 and 65 out of 218 TNBC patients were positive for MET in the cancer and adjacent tissues respectively. 142 and 30 out of 218 TNBC patients were positive for FASN in the cancer and adjacent tissues respectively. Positive expression of MET and FASN were significantly correlated with lymph node metastasis, pathological TNM, and pathological Stage. In addition, the positive expression of MET and FASN were correlated with recurrence and metastasis. The combined use of MET and FASN can better predict the survival condition.

Conclusions

Our results indicated that MET and FASN showed good predictive ability for TNBC. Combined use of MET and FASN were recommended in order to make a more accurate prognosis for TNBC.
Planting Systems for Modern Olive Growing: Strengths and Weaknesses
Authors: Lo Bianco Riccardo , Proietti Primo , Regni Luca , Caruso Tiziano
Published: May 2021

The objective of fully mechanizing olive harvesting has been pursued since the 1970s to cope with labor shortages and increasing production costs. Only in the last twenty years, after adopting super-intensive planting systems and developing appropriate straddle machines, a solution seems to have been found. The spread of super-intensive plantings, however, raises serious environmental and social concerns, mainly because of the small number of cultivars that are currently used (basically 2), compared to over 100 cultivars today cultivated on a large scale across the world. Olive growing, indeed, insists on over 11 million hectares. Despite its being located mostly in the Mediterranean countries, the numerous olive growing districts are characterized by deep differences in climate and soil and in the frequency and nature of environmental stress. To date, the olive has coped with biotic and abiotic stress thanks to the great cultivar diversity. Pending that new technologies supporting plant breeding will provide a wider number of cultivars suitable for super-intensive systems, in the short term, new growing models must be developed. New olive orchards will need to exploit cultivars currently present in various olive-growing areas and favor increasing productions that are environmentally, socially, and economically sustainable. As in fruit growing, we should focus on “pedestrian olive orchards”, based on trees with small canopies and whose top can be easily reached by people from the ground and by machines (from the side of the top) that can carry out, in a targeted way, pesticide treatments, pruning and harvesting.
Genetic Structure and Molecular Variability of Grapevine Fanleaf Virus in Sicily
Authors: Panno Stefano , Caruso Andrea Giovanni , Bertacca Sofia , Pisciotta Antonino , Lorenzo Rosario Di , Marchione Serafino , Matić Slavica , Davino Salvatore
Published: May 2021

Grapevine fanleaf virus (GFLV) is one of the main causes of grapevine fanleaf degeneration disease (GFDD) and is present in almost all areas where grapevine is cultivated. In this work, we ascertained the presence and spread of GFLV in different commercial vineyards in four Sicilian provinces (Italy), and its genetic structure and molecular variability were studied. In detail, a total of 617 grapevine samples of 11 autochthonous grapevine cultivars were collected in 20 commercial vineyards. Preliminary screening by serological (DAS-ELISA) and molecular (RT-PCR) analyses for ArMV (arabis mosaic virus) and GFLV detection were conducted. Results obtained showed the absence of ArMV in all the samples analyzed, while 48 out of 617 samples gave positive results to GFLV, for a total of 9 out of 11 cultivars analyzed. Phylogenetic analyses carried out on the GFLV-CP gene of 18 Sicilian GFLV sequences selected in this study showed a certain degree of variability among the Sicilian isolates, suggesting a different origin, probably as a consequence of the continuous interchange of GFLV-infected propagating material with other Italian regions or viticultural areas located in other countries.