bluuebunny/crossref_metadata_2025 huggingface dataset:
The Current Problem of the US Government Debt in the Context of Socioeconomic Inequality Regulation
Authors:   Financial University under the Government of the Russian Federation (Moscow, Russian Federation), Dorofeev Mikhail L.
Published: December 2021

Global debt has risen dangerously since the early 2000s, but most governments and central banks are more supportive of investors, because they keep printing money and buying back financial assets to provide markets and economy with liquidity. In this regard, we can see increasing concern not only about the growing debt burden of the world economy, but also about the impact of this problem on the dynamics of economic inequality. The aim of the work is to analyse and clarify the relationships between public debt and economic inequality in the USA for the period of 1910–2018. This study concludes that the level of economic inequality is not directly related to the specific level of public debt and changes under the influence of other factors, such as taxes and government spending on combating poverty, financed by the new government debt. Modern financial policies lead to increased economic inequality in wealth, which is confirmed by the data for most countries. In many developed countries, there is a progressive taxation system that curbs the rising income inequality. However, in most of them, there are complex tax relief and deduction systems for long-term investors, the problem of offshore and tax avoidance remains unresolved, which creates great obstacles to solving the problem of the growing economic inequality. In the context of the galloping inflation of financial assets, the growth rate of labor income is guaranteed to be lower than the growth rate of investment income. In the recommendations, the author justifies the modern problem of the public debt growth. The main risk in addressing this problem in the context of economic inequality regulation is the risk of increasing intergenerational economic inequality. We see how the tax burden is being transferred to future generations, while modern taxpayers have better opportunities to improve their quality of life, accumulate adequate pension capital and generally live with a higher level of financing of public goods. All this may not be the case for future generations of taxpayers due to the likely exacerbation of the debt problem in the future, since they will either have to pay more taxes on their income, pay a high inflation tax, or go to reduce public spending and finance public goods to solve the “unsolvable debt problem”. In this regard, the main recommendations today are to make every possible effort to contain the growth of public debt to a rate no higher than the growth of the economy; to develop a system of fiscal regulation of investor wealth and investment income; to optimize inheritance taxes; and, of course, to continue solving the problem of tax avoidance and offshore.
The Property and Economic Relations Scientific School of Aleksandr Bychkov, the First Doctor of Economics in Tomsk
Authors:   Tomsk State University (Tomsk, Russian Federation), Lozhnikova Anna V. , Khloptsov Dmitriy M. ,   Tomsk State University (Tomsk, Russian Federation), Bychkov Aleksandr Yu. ,   KAMELOT-A, OOO (Tomsk, Russian Federation), Сhernyak Mikhail E. ,   Tomsk State University (Tomsk, Russian Federation), Andreeva Irina E. ,   Tomsk State University (Tomsk, Russian Federation)
Published: December 2021

The article continues the series of articles in memory of Aleksandr Petrovich Bychkov, honorary citizen of Tomsk, rector of Tomsk State University (TSU) (1967–1983) and head of the Department of Political Economy of TSU (1966–1991). The article focuses on the fundamental scientific works of Aleksandr Bychkov as the founder of the Property and Economic Relations scientific school at the TSU Department of Political Economy. During his life (1921–2009), Professor Bychkov undoubtedly managed to build a successful model for the organization and development of scientific knowledge, and a system of continuous professional development for political economy instructors. Holding the high post of the TSU rector for a long time, Professor Bychkov managed to gather his associates in the field of economic education around himself and raise a lot of students and followers, numerous candidates and doctors of economic sciences, faculty and heads of political economy departments of universities in Siberia and the Far East. Professor Bychkov formulated and implemented a highly controversial long-term research program in two sectors (collective farms and the state) and two forms of public ownership in agriculture (kolkhoz–cooperative and state), from which his scientific school developed. Professor Bychkov traced the evolution from the emergence of a collective form of ownership to collective farm forms of land management. The fact that this research program deserves the status of a major scientific problem in the USSR is proved by the scientific session of the USSR Academy of Sciences on the history of peasant and collective farm construction in the USSR, held in Moscow in the period between Bychkov’s defenses of his candidate of science (1955) and doctor of science (1966) dissertations. According to Professor Bychkov, property relations in their economic essence should be separated from their legal expression and should include the entire set of production relations of people in the production, distribution, exchange and consumption of material goods.
Uncertainty Impact on Companies’ Investment Activities: The Case of Saint Petersburg and Leningrad Oblast
Authors:   Higher School of Economics (Saint Petersburg, Russian Federation), Rozmainskiy Ivan V. , Zubova Anna A. ,   JTI Rossiya (Moscow, Russian Federation)
Published: December 2021

The article proposes and tests the hypothesis that agents who feel uncertainty reduce investment in their business. The theoretical basis for this hypothesis goes back to the ideas of J.M. Keynes and his followers. According to these ideas, uncertainty is not measurable, and investment is determined by “cheerfulness”. We hypothesize that a strong sense of uncertainty can narrow the planning horizon – giving rise to investor myopia – and reduce the “degree of cheerfulness”, thereby reducing investment. Unique data on perceptions of uncertainty and incentives to invest were obtained from surveys of more than 400 heads of enterprises in Saint Petersburg and Leningrad Oblast in March 2018. Econometric analysis shows that this hypothesis cannot be rejected.
Impact of the Nature of Employment on the Quality of Working Life
Authors:   Tomsk Polytechnic University, Babyshev Vyacheslav Yu. , Barysheva Galina A. ,   Tomsk Polytechnic University, Tran Thi Bich Ngoc ,   Hanoi University of Science and Technology, Binh Dao Thanh ,   Hanoi University of Science and Technology
Published: December 2021

Technological and demographic changes have actualized the question of the influence of the nature of employment and the parameters of the workplace on the quality of a person’s working life. A scientific review and analysis of the impact of current trends in employment modes on the quality of human life is presented. Based on the literature review, it has been concluded that if there is unanimity among scientists about the positive impact of the regime of protected and standard employment on the quality of life, there is active debate about the impact of the regime of vulnerable and precarious employment. Also, based on the analysis of the literature, it has been determined that people’s subjective satisfaction does not always coincide with a positive impact on the objective quality of life. The study is based on comparative and correlation analysis as a method for processing statistical data from the OECD, ILO and WB. The employment regimes were classified according to four enlarged groups: economic sectors, professions, status, and employment regime. The assessments of the quality of life were classified according to three indicators: the human development index, the quality of life index and the international happiness index. The most important factors in the development of the labor market, influencing the quality of working life, have been identified: parameters of the quality of the workplace (the level of wages, employment stability, qualifications of workers, the level of social and legal guarantees) and the general level of employment. The most reasoned point of view was revealed: the regime of standard protected employment (permanent full-time work under a formal contract) has a positive effect, and the regime of precarious work (various options for informal, temporary or part-time employment) has a negative impact on the quality of life. The protected employment regime (hired labor and selfemployment as an entrepreneur) has a positive effect, while the vulnerable employment regime (individual self-employment and intra-family employment) has a negative impact on the quality of life. The transition to a “new” economy and highly skilled jobs has a significant impact on the quality of working life. The opinion of experts about non-standard forms of employment as a single category is refuted. The positive influence of the mode of part-time employment on the quality of life is revealed, the contradictory influence of the mode of temporary employment on the quality of life is shown. Achievement of material well-being and sociopolitical stability to a large extent contradicts the subjective happiness of people and the protection of the environment.
The Sunset of the Era of the Market Economy
Authors:   Polzunov Altai State Technical University (Barnaul, Russian Federation), Shvetsov Yuri G.
Published: December 2021

The article substantiates the assertive flaw in the theoretical platform of the market economy, proves the inevitability of the historical degeneration of both itself and the consumer society created on its foundation. The author characterizes the insoluble contradictions of the market economy – between labor and capital, exchange and use value of the technosphere and the biosphere; reveals the essence of the fetishization of money and the mechanism of functioning of the banking system as the legal successor of usury; substantiates the state of the limit of capitalism as the final phase of its development. The author emphasizes that commodity-money relations create an objective impossibility of harmonizing the interests of all members of society and lead to the dominance of the plutocracy class, which has subordinated all its natural, financial and labor resources. The author shows the unsightly role of the state in the decorum: it concentrated all its efforts on supporting the wealthiest strata of the population and actually left its least socially protected part to the mercy of fate. Attention is drawn to the fact that the transformation of money into capital, which increases simultaneously with the growth of the size of commercial activity, led to a complete alienation from labor and doomed workers to poverty and misery. The author shows that, under the conditions of private ownership, the utilitarian purpose of the goods, which is expressed in use value, is replaced by the parameter of its prestige, reflecting mainly exchange value, which distorts the normal balance of supply and demand in society, and is a source of unproductive consumption. The article proves the inefficiency and social injustice of distribution relations in the field of environmental management, which leads to the concentration of rent payments in the hands of the oligarchy and the elimination of the institution of public consumption funds. The abrasion of the market economy is substantiated, within which the internal contradictions accumulated over time cannot be resolved and lead to a breakdown of the model of production relations.
Human Capital as an Interdisciplinary Category: A Structured Research Review
Authors:   Tomsk State University (Tomsk, Russian Federation), Minaev Nickolay N. , Zharova Ekaterina A. ,   Tomsk State University (Tomsk, Russian Federation)
Published: December 2021

In the present study, the authors attempt to systematically consider the amount of accumulated scientific knowledge about human capital. A critical analysis of the array of research works allows seeing the full coverage of various aspects of human capital, eliciting problem areas, and defining possible trajectories for the development of the theory of human capital. The above explains the aim of the study, which is to analyze the works of domestic and foreign researchers on key aspects of the theory of human capital and to form a critical view of the degree of knowledge of these aspects. To reach the aim, the authors selected a representative sample of works by domestic and foreign authors, analyzed the content of the selected works, and made a review reflecting the key aspects of the theory of human capital and the degree of their study. The research methodology the authors used includes a systematic approach and analysis, and a tabular method. The results obtained indicate that by now the key aspects of the theory of human capital have sufficient research coverage. On the other hand, the diversity of researchers’ views, approaches and methods has led to a lack of a single opinion on a number of significant issues in the academic community. As a result, it hinders the further development of the theory of human capital and its successful application. Thus, at present, there is no generally accepted and well-established definition of human capital and a unified understanding of its socioeconomic essential nature. Changes in the essential nature of human capital under the influence of transformational processes occurring in modern society are not revealed. There are no relevant works of the past two to three years covering the role of human capital in regional development, while this topic is significant for Russia. There is no generally accepted methodological framework for assessing the value of human capital at the regional level, which hinders the analysis of accumulated human capital and trends in this process. In the field of analysis of factors of human capital accumulation, there are no works that highlight factors that affect the implementation of existing human capital. There are no works that reflect methodological approaches to managing the accumulation and distribution of human capital. Thus, the authors come to the conclusion that one of the most relevant directions in the further development of the theory of human capital can be the development of an inter-territorial (interregional) balance of human capital. This strand of research should cover a wide range of issues, including the development of methodological tools for assessing the accumulated value of human capital, identifying trends and factors that affect its distribution and final use, and developing approaches to managing the accumulation and rational distribution of human capital.
Identification and Assessment of Social Risks of the State in the Far East Territories with a Special Economic Status
Authors:   Far Eastern Federal University (Vladivostok, Russian Federation), Kadermyatova Anastasia E. , Sinenko Olga A. ,   Far Eastern Federal University (Vladivostok, Russian Federation)
Published: December 2021

The article presents a study of the social risks of the state in special economic, legal, and organizational regimes using the example of territories with a special economic status in the Russian Far East. An important condition for the creation of special territories for the state is the compensation for the provided preferences in full with benefits in the future. The article contains a content analysis of foreign and domestic literature, based on which the social risks of the state are identified taking into account the specificity of the special territories of the Far East. The authors compile a map of social risks based on the main goals of the creation and development of special territories, and highlight a separate classification feature of the state’s social risks – the non-fulfillment of guarantees for the population. The authors also reveal the problems of justifying indicators for assessing risks. Based on the grouping, analysis and comparison of the official statistical information of Rosstat and the RF Ministry of Economic Development, the authors assess the identified social risks of the state in the Russian Far East territories with a special economic status. The article defines the probability and hazard category of each risk.
GESTURE IN THE UDMURTS SONG CULTURE: FUNCTIONS AND SEMANTICS
Authors:   Udmurt Institute of History, Language and Literature, Udmurt Federal Research Center of the Ural Branch of Russian Academy of Sciences (Izhevsk, Russian Federation), Nurieva Irina M.
Published: December 2021

The problems of non-verbal behavior remain in the shadow of the modern ethnomusicology so far. Meanwhile, spatial behavior of singers, the poses and gestures used by them during the singing are language of culture, not less informative, than musical and verbal language, but at the same time more emotional, expressive and available. Gesture as body language is usually associated with the movement of the arm, palm, head, shoulders, legs. In the present study, we operate with the broader meaning of the word “gesture” as a behavior (from Lat. Gestura). The spatial behavior of performers during the ceremony, the generally accepted postures and gestures as non-verbal language of culture are discussed in the article on the material of the Udmurt ritual song tradition. The forest landscape influences the behavioral, as well as linguistic, religious, sound picture of the world of the Finno-Ugrians. The connection between the natural geographic environment and the “mental warehouse” of the Udmurts was observed by ethnographers as early as the end of the 19th century; they noted restraint in expressing impressions, silence, extraordinary shyness and the boundless ability of Udmurts to endure. The same is noted by modern scientists. In speech communication, for example, there is an unspoken rule not to express loudly and openly your emotions; it is not customary to actively gesticulate, to speak loudly. The findings of scientists suggest that the Udmurt communicative culture belongs to the low-kinesic. The stereotypes about the modesty and timidity of the Udmurts collapse when analyzing the Udmurt rituals, in which the idea of producing magic dominates to extend the genus or future harvest. Many behavioral prohibitions are not only lifted; moreover, obscene gestures, indecent behavior are becoming a necessary condition for rituals. Singers can stomp their feet heavily, beat the rhythm with loud beats of iron objects, sing while standing on chairs. In other local traditions, the magic of production can be embodied in the body language of singers in slow rocking, round dances. The key moment of the spatial behavior of the singing participants of these rites is a side-to-side movement as a symbol of the growth of cereal crops. Ritual gestures of a handshake, bowing of the knees as communicative gestures are considered in the article. Other gestures of singers (alternating between the left and right foot subhemps, putting the palm to the mouth while singing) are designed to enhance the expressiveness of the musical rhythm or create a special sound effect. It is concluded that the song ritual communication of the Udmurts, in contrast to everyday verbal communication, is characterized by a higher level of emotionality, which is reflected in body language.
QUEST AS A FORM OF WORK WITH READERS (ON THE EXAMPLE OF TOMSK LIBRARIES)
Authors:   Tomsk State University (Tomsk, Russian Federation), Kuzoro Kristina A. , Zhukova Maria M. ,   Khakass Institute for the Development of Education and Advanced Training (Abakan, Russian Federation)
Published: December 2021

Quest is an increasingly popular form of holding events in modern libraries. The quest allows readers to develop general cultural and professional competencies, teamwork skills, creative interaction, and quick decision-making. This form of work is used to acquaint readers with the library, its structure and resources; to help students in mastering academic disciplines; to present information on any topic in an attractive and innovative format. Quests help to develop interest in reading, creativity of local authors, local history research, environmental protection. During the game, participants solve logical problems, search for the necessary information, learn to work with information resources. The quest allows you to master new material in an easy and interesting way, to master any new skill. In addition, the form of the quest corresponds to the way of thinking of the modern young generation. The use of quests in educational activities is due to the fact that this technology provides for a quick switch of attention, efficiency, change of tasks. The purpose of the conducted research: systematization and analysis of the practice of using quests in the libraries of Tomsk, identification of positive experience, determination of the prospects for using this form of work with readers. The experience of the Scientific Library of Tomsk State University, Tomsk Regional Universal Scientific Library named after A.S. Pushkin, Tomsk Regional Children's and Youth Library, Municipal Information Library System of Tomsk was analyzed. The source base was analytical reports of libraries and news information posted on their websites.
LIBRARY AND INFORMATION PEDAGOGY IN THE STRUCTURE OF MODERN LIBRARY AND INFORMATION EDUCATION
Authors:   Tyumen State Institute of Culture (Tyumen, Russian Federation), Maslakova Maria V. , Tolstoukhova Irina V. ,   Tyumen State Institute of Culture (Tyumen, Russian Federation)
Published: December 2021

Increasing information and condensing the speed of information technologies constantly transforms the functionality of libraries (as information, cultural, educational organizations) to solve acute problems, for example, informational, cultural, educational and educational education and development of readers in the new information space. Modern society sets itself each time new tasks and methods for the development of pedagogical sciences, most often they are associated with an informational approach to learning, education and cognition. The impact of information processes on the education and training and retraining of new library and information professionals is acutely affected. Allocation of information pedagogy allows us to explore new information processes and pedagogical phenomena to develop the sectoral aspect of pedagogical science. Library pedagogy is aimed at training competent specialists in the field of library information and pedagogical activity, functionally oriented to the training, education, and development of library readers. Library and information activities accumulate in themselves different types of labor processes, representing the library as the center of cultural, social, informational and pedagogical beginnings. The authors of the work propose the formulation of scientific knowledge – «library and information pedagogy», as the most appropriate to the name of the «Library and information activity» training area within the framework of the current federal state educational standards 51.03.06 and 51.04.06 «Library and information activities». Library-information pedagogy is a comprehensive knowledge of library pedagogy, pedagogy in general, as well as information pedagogy, including: the pedagogical basis of library science, the information basis of information, library and educational processes, the information worldview, pedagogical competencies that will allow the use of new information and communication technologies in the theory and practice of library and information activities. The structure of library and information pedagogy is conditionally composed of three main components: the base, core and effect. Considering the fact that at present there is no such scientific discipline as library and information pedagogy, then for the modern generation of students, in the context of the implementation of professional standards, the transition to FSES 3 ++, the emergence of a new position «teacher-librarian», it could be very useful. So, the use of the library-information approach in pedagogy makes it possible to replace the traditional plane of the problematic of pedagogical research of the educational and educational processes with the problematics of library-information activity in the implementation of these processes.
ATYPICAL CORPOREALITY AS A SOCIAL CONSTRUCT AND THE INCLUSION PROBLEM IN THE RUSSIAN EDUCATION SYSTEM
Authors:   National Research Tomsk Polytechnic University (Tomsk, Russian Federation), Lukianova Natalia A. ,   National Research Tomsk State University (Tomsk, Russian Federation),   Yaroslav-the-Wise Novgorod State University (Veliky Novgorod, Russian Federation), Shavlohova Anna A. ,   National Research Tomsk Polytechnic University (Tomsk, Russian Federation)., Fell Elena V. ,   National Research Tomsk Polytechnic University (Tomsk, Russian Federation)
Published: December 2021

The article deals with the issue of stereotyping disability in Russia and the Russian education system. As educators make attempts to ensure that people with disabilities begin to access quality education in Russia, results often disappoint. Aiming to uncover the fundamental reasons that underpin failures in the implementation of inclusive practices, the authors suggest that the perception of disability understood as the social construction of atypical corporealityconditions the implicit understanding of what inclusive education is.The purpose of this article, therefore, is to identify the specific features of the social construction of atypical corporeality and explore ways in which these features are manifested in educational practices. Accordingly, the complexity of the object of study determined the need to refer to a wide range of methodological frameworks of cultural, semiotic and constructionist schools, which allowed the authors to determine the coding methods involved in the social construction of an atypical body. The theoretical investigation allowed the authors to conclude that the construction of atypical corporeality is the outcome of an underlying social agreement regarding the implementation of a particular model of disability (in particular, the article compares the social and medical models). Furthermore, a comparative analysis of educational practices used in the systems of inclusive education in conjunction with the problems of the body in society reveals the inconsistency of their implementation in Russia. Consequently, the authors conclude the article by outlining the key conditions for the social construction of atypical corporeality. Moreover, they identify the following controversy as the main obstacle preventing the implementation of effective inclusion practices into the Russian education system: while declaring the adherence of the “social model” of disability, the Russian education system continues to rely on the medical understanding of the body persistently implementing the medical model.
Exploring early childhood centre managers’ perceptions of their roles in promoting developmentally-appropriate physical environments in South Africa
Authors: MODİSE Matshediso Rebecca
Published: December 2021

The aim of this research was to explore the roles of Early Childhood Centre managers in promoting developmentally appropriate physical environments from birth to four-year-old children in South Africa, and then draw implications on the quality of leadership in the centres. While significant studies have been conducted on the phenomenon globally, little has been published on how centre managers understand their roles in promoting developmentally appropriate physical environments for infants and toddlers in the country. The researcher had a conviction that the quality of a physical environment in early childhood centres has a form of influence on the development of a child. This research was based on Merton (1957)’s Role Theory which frames an understanding of the behaviour of a group or individual(s) within a, particularly educational setting. This was further paired with a structural-functionalism paradigm, where every individual’s place and corresponding role in a social or organisational structure is appreciated. Five South African centre managers within rural communities of Gauteng North District were purposively sampled for this empirical investigation. A qualitative approach with case study design using semi-structured interviews, spot observations and taking good quality photographs in collecting data was employed. The study established that some manager-participants were cognisant of their leadership role in constructing developmentally appropriate physical environments, whilst others were unaware or oblivious of their role and influence. In addition, results also allude to potential gaps in how centre managers understand and interpret policy and curricula to fashion and sustain developmentally appropriate physical environments amid contextual challenges. The researcher, therefore, recommended that the Education Department in the country develop a strategic plan to develop leadership skills in centre managers.
Obtaining and research of pharmaceutical properties of antiemetics in a form of powder for inhalation
Authors: Ivanov Igor M. , Pechurina Tatiana B. , Vengerovich Nikolai G. , Yudin Mikhail A. , Nikiforov Aleksandr S. , Raguzin Evgenii V. , Kuzmich Vladimir G. , Proshina Yulia A.
Published: December 2021

Samples of antiemetic drugs (ondansetronum, palonosetronum, metoclopramidum) in the form of powder for inhalation have been developed by the method of spray drying. The granulometric composition, hygroscopicity and aerodynamic distribution of aerosol particles of the drugs have been investigated. The dosage form of the powder for inhalation of antiemetics (ondansetronum and palonosetronum) in terms of its particle size distribution, hygroscopicity and content of the agent corresponds to those for inhalation using dry powder inhalers. In the study of the phase-dispersed composition of aerosol, ondansetronum and palonosetronum in the dosage form of powder for inhalation as part of the HandiHaler inhaler (at a flow rate of 60 l/min) showed high rates of the released dose up to 7276%, respirable particle fraction (up to 5 m) up to 5456% and a mass median particle size of about 3 microns. Obtaining the inhaled form of metoclopramide requires optimization of the production method for receiving the product with acceptable pharmaceutical properties.
Investigation of the properties and activity of DfCas9 and DsCas9 nucleases in eucaryotic cells
Authors: Vlasova Yelizaveta V. , Madera Dmitry A. , Gershovich Pavel M.
Published: December 2021

This study is focused on the two novel nucleases of the CRISPR/Cas9 family, which were found in bacterial genomes of DfCas9 (Defluviimonas sp) и DsCas9 (Demequina sediminicola). Discovery of these nucleases was part of the results of a joint study conducted by BIOCAD together with Skoltech Institute of Science and Technology and Saint-Petersburg Polytechnical University (SPPU) under a grant agreement with the Department of Science and Education of Russian Federation (Agreement number 14.606.21.0006 from September, 26th 2017). Under the agreement the nucleases DfCas9 and DsCas9 were characterized in vitro by Skoltech and SPPU.

Based on the aforementioned results, in this study we characterized the genome-modifying nuclease activity of these enzymes in a mammalian cell line HEK293. Specifically, we created genetic constructs designed to express the nucleases DsCas9 and DfCas9 together with the necessary guide RNA molecules (sequences of the guide RNAs were described previously) [1]. We demonstrated expression of the nucleases on a protein level, as well as activity of DfCas9 at the VEGF2 locus in HEK293 cells. The theoretical study was conducted by analyzing international and national literature. The experimental part was performed with a restriction-ligation cloning method, transient transfections, Western blot protein detection method, and a T7 nuclease-based method of detection of heteroduplex double-stranded DNA.
A Social Network Structure Analysis of Former Smokers in Emerging Markets Using China’s Twitter
Authors: Xiaobo Tao , Ziniu Jin
Published: December 2021

Objectives: Social networks are widely used for proping the process of tobacco control in emerging markets, but their formation and effects are not well understood. Using the micro blogging platform Sina (Sina Weibo, China’s Twitter) as an example, this article conducts a multi-agent
simulation analysis of the Netlogo platform to analyze the micro-level behavioral characteristics of former smokers and macro-evolutionary law in the formation of social networks in emerging markets. The results show that the tobacco control in use of social networks have two characteristics:
limitations on the size of the network and the in-degree and out-degree of its nodes as well as heterogeneous attributes of the nodes. This kind of network is better at simulating a real social network than small-world and scale-free networks.
Curative Effect of Tumor Resection under Microscope for Brain Glioma based on Humanized Nursing Model
Authors: Huang Lifeng , Xiang Haiyan , Qian Weiming
Published: December 2021

Previous studies have shown that microsurgery has two main roles in glioma resection, that is, the nerve function is well protected and the degree of tumor resection is improved. On the basis of this experiment, the curative effect of tumor resection under microscope for glioma was
studied based on humanized nursing model. By randomly dividing 64 patients into two steps and comparing them in many aspects, the study mainly obtained two inspirations: microglioma resection has good effect, and humanized nursing mode has good effect on postoperative recovery. Finally, some
Suggestions and principles for microglioma resection were put forward: the principle of timely operation after diagnosis, the principle of complete resection for nonfunctional areas, the principle of protection for important functional areas, and the principle of recovery plan confirmed by
disease examination after surgery. In addition, in terms of the influence of humanized nursing mode on the treatment of glioma under the microscope, the data statistics and SPSS tests show that humanized nursing mode can effectively improve the satisfaction of patients and their families.
Relieve anxiety and depression and help patients recover; Lower scores in pain rating statistics, etc. In addition, this experiment has a good basis for development, and all the 64 patients successfully completed the operation without serious complications, which further verified the above
conclusions, namely, the maturity and reliability of the technique of microscopic tumor resection for glioma. The technique of tumor resection under microscope can be used in combination with humanized nursing mode, which has good promotion value.
Analysis of the Effect of Psychological Nursing Intervention on Perioperative Mood and NK Cell Activity in Breast Cancer Patients
Authors: Yuan Jihong , Yuan Linghong , Hu Yi , Gong Jingjing , Tong Yang , Jin Yongmei
Published: December 2021

Breast cancer (Breast Cancer, BC) is one of the most common malignant tumors in women in the world. It is the first malignant tumor that causes the death of women in developing countries. It seriously threatens the lives and health of women and causes damage to the family, economy
and society. Through psychological nursing intervention, it has a positive effect on the perioperative mood and NK cell activity of breast cancer patients. The purpose of this article is to explore the effects of psychological intervention on the perioperative mood and NK cell activity of
breast cancer patients. This article is based on the concept and theory of psychological nursing intervention for female breast cancer patients, and establishes personalized intervention measures in conjunction with clinical practice to intervene the emotions of breast cancer patients during
the perioperative period. This article analyzes the nature, intensity, and causes of negative psychology of the subject through in-depth understanding of the subject’s psychological emotions, coping ability, personality characteristics, past emotional experience, and social support,
and discovers the different emotional characteristics of the patient, and formulates the personality psychological intervention measures to stimulate positive and optimistic attitudes and ease the degree of negative psychology. This article analyzes the psychological characteristics of several
breast cancer patients. Take corresponding psychological intervention measures. Cope with a series of bad psychology caused by image damage caused by total mastectomy. The results and data in this article show that the incidence of anxiety and depression in the control group is higher than
that of the psychological intervention group at 7 days after the operation, with P values of 0.0059 and 0. 0215.Psychological intervention reduces the incidence of negative emotions and reduces the negativeness of patients. The intensity of emotion has played a good clinical effect.
Correlation between Vitamin A Deficiency and the Severity of Mycoplasma Pneumoniae Pneumonia in Children
Authors: Wang Teng , Zheng Ping , Jiang Qian , Sun Qianqian
Published: December 2021

Mycoplasma pneumoniae pneumonia is a problem that has attracted the attention of children’s respiratory department in recent years. The relationship between vitamin A deficiency (VA) and the severity of Mycoplasma disease (MPP) in children was studied. In this paper, the hospitalized
children with Mycoplasma pneumoniae pneumonia (MPP) in our hospital were selected as the research objects, and they were divided into common type and refractory type (RMPP) for comparative experiment. The VA and immunoglobulin levels of the two groups were compared. Attention should be paid
to the normal ratio of VA deficiency (CVAD) and sub deficiency (svad) in the two groups. In this paper, the relationship between infection, immunoglobulin level and VA level was analyzed. The results showed that CVAD was 27.27% in MPP group and 63.75% in RMPP group. Comparison of immunoglobulin
levels between the two groups: the levels of IgM, IgA and IgG in the normal MPP group were significantly lower than those in the RMPP group. On the other hand, the detection rate of CVAD was 81.48% in RMPP with infection and 54.72% in RMPP without infection. The detection rate of CVAD in patients
with infection was significantly higher than that in patients without infection. There was a correlation between VA Deficiency and MPP classification.
Relationship between Ag-NORs and T Lymphocyte Subsets in Children with Epilepsy
Authors: Zhong Hongping , Cheng Xiaoning , Yan Peiqiang
Published: December 2021

With the acceleration of the pace of life, the number of children with epilepsy is increasing. This study was to investigate the relationship between Ag-NORs and T lymphocyte subsets in children with epilepsy. In the morning, 3ml of elbow vein blood was collected from epileptic children
on an empty stomach. After standing at room temperature for 0.3-1 hour, the serum was centrifuged (2000 rpm, 4 minutes). 3 ml of mixed venous blood was collected in EDTA-K2 vacuum container. The sample was taken out within 5 hours after staining. 30 n I of Itcite reagentand 30 n I of anticoagulant
were put into TruCount tube and mixed evenly. Then flow cytometry was used for detection, and facscomp software was used for automatic inspection and calibration. In the same way, the automatic analysis software muitiset was used to obtain 20000 white blood cells, count 8000-10000 lymphocytes
automatically, and calculate CD4 + T lymphocytes, CD8 + T lymphocytes and CD4 + / CD8 + ratio. Ag-NORs detection: under aseptic conditions, 0.5ml anticoagulant blood was added into the medium flask containing rpm-1640 and incubated in the incubator at 37°C for 72 hours. After mixing the
cell suspension at room temperature, put it into a 10ml glass tube, heat it and dry it. Wait until the temperature of the water solution tank rises to 80-90 °C, and then put aluminum plate on it. The staining was placed under the microscope on the stage, and the image was adjusted to make
the image analysis program effective. The ratio of nuclear area to nuclear silver staining area of 30 lymphocytes was counted. This ratio reflects the content of Ag-NORs in the nucleolar forming region of T lymphocytes. The ratio of Ag-NORs area to nuclear area was 0.32 ± 0.03, 0.38
± 0.03 and 0.46 ± 0.03, respectively. This study is helpful to provide guidance for the treatment of epilepsy in children.
Predictive Values of Serum Progesterone, Human Chorionic Gonadotropin and CA-125 for Pregnancy Outcomes of Threatened Abortion and Subchorionic Hematoma
Authors: Li Ran , Wang Yan , Zhu Xiaohe
Published: December 2021

Objective: We aimed to study the predictive values of serum progesterone (P), human chorionic gonadotropin (HCG) and CA-125 for the pregnancy outcomes of threatened abortion complicated with subchorionic hematoma (SCH).

Materials and methods: Sixty women with threatened
abortion and SCH in 6-1 Oth gestational week, 60 with threatened abortion only and 60 healthy pregnant women were selected as groups A-C respectively. Levels of β-HCG, P, estradiol (E2) and CA-125 in peripheral venous blood were measured by chemiluminescence assay. Serum levels of INF-γ,
TNF-α, IL-2, IL-4 and IL-10 were detected by ELISA.

Results: Serum β-HCG, P, CA-125 and E2 levels of group A were significantly lower than those in group C (P<0.05). Groups A and B had significantly higher INF-y, TNF-a and IL-2 levels but lower IL-4 and IL-10 ones than
those of group C (P<0.05).The hospitalization and vaginal bleeding times of group A were significantly longer than those of groups B and C (P<0.05). The success rate of fetal protection, neonatal body weight and gestational age of groups A and B were significantly lower than those of
group C (P<0.05). Serum P, E2 and HCG levels were low in women with threatened abortion and SCH in early pregnancy, but CA-125 level was high, accompanied by increased INF-γ, TNF-α and IL-2 together with decreased IL-4 and IL-10.

Conclusion: The onset and progression
of SCH may be related to imbalance between T lymphocyte factors towards Th1 direction.
Responding Strategies for The Covid-19 In Digestive system Diseases Center in Wuhan and Haikou City
Authors: Bian Lidan , Li Hua , Wang Xuanxuan , Chen Jiao , Cheng Hongping , Wu Xiaowei , Gong Xun
Published: December 2021

Since first being recorded late last year in China, Coronavirus Disease 2019(Covid-19), which is highly contagious and can trigger severe respiratory symptoms1, has spread around the world and been declared a pandemic by the World Health Organization.

As the
largest hemodialysis center in wuhan city, which was the outbreak’s epicenter,there was more than 600 patients undergoing hemodialysis therapy in our setting.The crowds with high mobility made it more difficult to prevent and control of COVID-19 cases than that in general population.Along
with the end of lockdown in wuhan city,some patients recovered and returned from COVID-19 designated dialysis settings,we took messuares accordingly.Now we share our experience of prevention and control for COVID-19 in a large non-designated dialysis center of WuHan city.
Ivermectin Derivatives: A Pivotal Anti COVID-19 Drug Molecules Blocking the Manifestation of Coronavirus
Authors: Wang Shiya , Zou Cao , Liu Xiofeng , Yan Yonjin , Gu Shunzhong , Li Xun
Published: December 2021

In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. Notably, on January 30, 2020, the World Health Organization declared the outbreak
as a pandemic and is of International Concern. Perceived risk of acquiring disease has led many governments to issue control measures. Recently, numerous studies demonstrated the drug molecules controlling the COVID-19 are ongoing and some have reached to the clinical trial phase III. However,
none of them are worthy in controlling the corona virus. We hypothesized that derivatives of FDA approved drugs Ivermectin may block the manifestation of Coronavirus. Here, we used MTT assay to check damage levels in the lung’s cells affected with coronavirus. In conclusion, we showed
that derivatives of Ivermectin, an FDA approved drugs possess a powerful efficacy as an anti-COVID-19 drugs.
Analysis of Cigarette Rolling Brand Marketing Strategy Under the New Normal of Tobacco Economy
Authors: Enze Fan
Published: December 2021

Objectives: In order to study the communication channels and modes of tobacco brands, cigarette rolling brand marketing strategy under the new normal of tobacco economy is researched in this paper. Methods: T city is selected as the research sample of cigarette brand construction
and marketing. Through the analysis of the current situation of T City, this paper puts forward the guiding ideology of cigarette cultivation, and puts forward the basic strategy system of brand marketing. Results: Brand building is a scientific process. The tobacco industry must avoid brand
building speculation, because the opportunity cost of brand reconstruction is huge, and there is a risk of completely losing market dominance. The foundation of brand building is to convert the buying point with zero cost selected by target customers into the selling point of products to obtain
pricing power. Conclusion: The advantages of tobacco brand’s own products should be transmitted to target customers through planning from three aspects: the first is to clarify the competitive advantages of its own products; the second is to refine the core value of the brand; the third
is the dissemination of brand positioning.
The Principle of Administrative Law and Judicial Application Based on E-commerce Model
Authors: Sun Haitao
Published: December 2021

Objectives: As a principle that controls the rational exercise of administrative power, the principle of proportionality is adopted by other legal systems because of its reasonable structure and effective control of administrative power. Methods: In this paper, in the information
technology environment of mobile internet and based on the e-commerce model, the proportional principle of administrative law and its judicial application were studied. Results: Mainly the principle of proportionality in administrative law was introduced into the e-commerce negotiation system.
A specific example in the context of e-commerce was selected to simulate the entire automatic negotiation process. Conclusion: The simulation experiment results were analyzed and summarized, which shows the advantages of the automatic negotiation mechanism proposed in this paper.
Analysis of the Influencing Factors of Team Creativity to Organizational Innovation Based on QCA Analysis
Authors: Ye Changyou , Song Xiaowei , Fang Zhen , Gao Ke
Published: December 2021

Objectives: Psychological capital is the core element that represents individual initiative, which lays an important foundation for individual to gain competitive advantage. In the team organization, the employee’s active psychological resource is the main source of the organizational
innovation power. Therefore, the factors that influence the organization innovation based on the team creativity of QCA analysis are analyzed in this paper. Methods: Based on the analysis of the basic principle of psychological capital and the atmosphere, motivation and performance of team
innovation, the mechanism of interaction between mental capital and team innovation, it is found out that innovation is the embodiment of employee psychological capital are explored in this paper. Results: And a model of innovation power based on psychological capital is proposed. The validity
and reliability of the model are validated by QCA analysis. Conclusion: The simulation results show that the research has found out the mechanism of team creativity on organizational innovation, and it has a good reference meaning and application value to improve the creative power of team
innovation.