bluuebunny/crossref_metadata_2025 huggingface dataset:
Computed Tomography-Based Investigation on the Effects of Intravenous Bisphosphonate Administration on Tooth Growth in a Minipig Animal Model
Authors: Poxleitner Philipp , Voss Pit , Steybe David , Seibert Lisa-Marie , Zeiter Stephan , Stoddart Martin , Schmelzeisen Rainer , Otto Sven
Published: June 2022

Background and Objectives: The objective of this study was to evaluate the effects of bisphosphonate (BP) administration on tooth growth, using CT-data of a minipig animal model investigation. Materials and Methods: Tooth growth was evaluated in minipigs, with eight animals receiving weekly zoledronate (ZOL) and three animals serving as the control group. Tooth growth was evaluated at the right 2nd molar (M2) in the maxilla. A computed tomography-based measuring method was applied to evaluate tooth growth in the coronal-apical, buccal-oral and mesial-distal axis. Results: ZOL-administration was found to impact tooth growth in all evaluated measuring axes, with the highest effect observed in the coronal-apical axis. Conclusions: Detrimental effects of BP administration on growing teeth have been reported by a number of investigators. The results of this investigation demonstrate that intravenous ZOL affects the growth of the whole tooth within a short period of administration. With BPs being administered to a growing number of pediatric patients, further studies should be conducted to qualify and quantify the effects of BPs on developing teeth.
Oversight and Management of Women with Psoriasis in Childbearing Age
Authors: Bucur Ștefana , Savu Alexandra-Petruța , Stănescu Ana Maria Alexandra , Șerban Elena-Daniela , Nicolescu Alin-Codruț , Constantin Traian , Bobircă Anca , Constantin Maria-Magdalena
Published: June 2022

Psoriasis is a complex disease with many associated comorbidities, all of which have a negative impact on a patient’s personal, social, and sexual life. There are some unique considerations in the effects of this disease among women. The average age of diagnosis in women with psoriasis is 28 years, and this onset corresponds to the fertile life of women. There is conflicting information about the effects of psoriasis on female fertility. Some studies suggest that this condition’s associated comorbidities, personal behaviors, and reduced ovarian reserve, especially due to chronic inflammation, affect women’s fertility. Another possible reason women with psoriasis are less likely to become pregnant is that their sexual intercourse frequency decreases after the condition’s onset. The available information on the effects of pregnancy on women with psoriasis is limited. According to current evidence, most women will experience an improvement in their skin condition. Studies show that patients with moderate-to-severe psoriasis are more prone to experience pregnancy complications. The management of pregnant and lactating women with psoriasis is also difficult, as the safety profile of commonly used drugs in patients with psoriasis is not entirely known.
Anatomy, Biomechanics, and Reconstruction of the Anterolateral Ligament of the Knee Joint
Authors: Park Jun-Gu , Han Seung-Beom , Lee Chul-Soo , Jeon Ok Hee , Jang Ki-Mo
Published: June 2022

Despite remarkable advances in the clinical outcomes after anterior cruciate ligament reconstructions (ACLRs), residual rotational instability of the knee joint remains a major concern. Since the anterolateral ligament (ALL) on the knee joint has been “rediscovered”, the role of anterolateral structures, including ALL and deep iliotibial band, as secondary stabilizers of anterolateral rotatory instability has gained interest. This interest has led to the resurgence of anterolateral procedures combined with ACLRs to restore rotational stability in patients with anterior cruciate ligament (ACL) deficiencies. However, the difference in concepts between anterolateral ligament reconstructions (ALLRs) as anatomical reconstruction and lateral extra-articular tenodesis (LETs) as non-anatomical reinforcement has been conflicting in present literature. This study aimed to review the anatomy and biomechanics of anterolateral structures, surgical techniques, and the clinical outcomes of anterolateral procedures, including LET and ALLR, in patients with ACL deficiencies.
A Bibliometric Analysis (2010–2020) of the Dental Scientific Literature on Chemo-Mechanical Methods of Caries Removal Using Carisolv and BRIX3000
Authors: Bratu Dana Cristina , Nikolajevic-Stoican Nicoleta , Popa George , Pop Silvia Izabella , Dragoș Bianca , Luca Magda-Mihaela
Published: June 2022

Reports in the literature have proposed and analyzed several minimally invasive techniques for caries removal in recent decades. In light of recent events surrounding the ongoing epidemiological context, concerns have been raised regarding the generation of aerosols during dental procedures. The aim of our research was to provide an overview of the scientific literature on the topic of chemo-mechanical caries removal (CMCR) methods, focusing on two products (Carisolv, BRIX3000), commercially available in Europe. A bibliometric analysis was used to investigate the scientific articles included in Web of Science (WoS) Core Collection database, published from January 2010 to December 2020. We analyzed the co-occurrence of all keywords (Author Keywords and the KeyWords Plus section), co-authorship and co-citation, using the free software VOSviewer. Our bibliometric analysis revealed a worldwide interest in the subject of chemo-mechanical methods of caries removal, which has transcended the area of pediatric dentistry. The analyzed studies have been conducted mainly in high-income countries that have developed sanitary policies regarding prevention and early treatment of carious lesions as a health priority.
Impact of Sex on the Association between Flexibility and Arterial Stiffness in Older Adults
Authors: Yoo Tae-Kyung , Park Soo-Hyun , Park Sae-Jong , Lee Jong-Young
Published: June 2022

Background and Objectives: Flexibility is one of the most important physical fitness parameters in the geriatric population. Brachial–ankle pulse wave velocity (baPWV) is a measure of systemic arterial stiffness. However, data on the association between flexibility and arterial stiffness in the older adult population are limited. Therefore, we aim to investigate this association by using the sit-and-reach test (SRT) and measuring baPWV. Materials and Methods: We reviewed data from the 2014–2015 Korean Institute of Sports Science Fitness Standards Project. Individuals older than 65 years with SRT and baPWV data were included. A generalized linear regression analysis was conducted to assess the association between flexibility and arterial stiffness. Multiple relevant confounding factors were adjusted. Results: A total of 615 individuals were included in the analysis. The mean age of the male and female participants was 71.44 ± 4.42 and 70.64 ± 4.13 years, respectively. The mean SRT result was 6.58 ± 9.97 and 18.04 ± 7.48 cm, respectively. After multivariable adjustment among the male participants, the higher SRT result tertiles were inversely associated with baPWV (β (95% confidence interval): 3.11–11.00 cm, −74.45 (−140.93, −8.55); ≥11.01 cm, −108.17 (−177.65, −38.70)) in comparison with the lowest tertile. The female participants did not show any significant correlation between the SRT result and baPWV. Conclusions: Our results suggest an inverse association between trunk flexibility and systemic arterial stiffness, expressed as the SRT result and baPWV, respectively, in older Korean men but no association in older Korean women. Sex differences might influence the association between flexibility and arterial stiffness in the older adult population.
Membrane and Membrane Bioreactors Applied to Health and Life Sciences
Authors: Salerno Simona , Drioli Enrico , De Bartolo Loredana
Published: June 2022

The interest in membranes and membrane bioreactors for health and life sciences is rapidly growing thanks to their wide applications in advanced therapies and biotechnologies [...]
Reagent-Free Immobilization of Industrial Lipases to Develop Lipolytic Membranes with Self-Cleaning Surfaces
Authors: Schmidt Martin , Prager Andrea , Schönherr Nadja , Gläser Roger , Schulze Agnes
Published: June 2022

Biocatalytic membrane reactors combine the highly efficient biotransformation capability of enzymes with the selective filtration performance of membrane filters. Common strategies to immobilize enzymes on polymeric membranes are based on chemical coupling reactions. Still, they are associated with drawbacks such as long reaction times, high costs, and the use of potentially toxic or hazardous reagents. In this study, a reagent-free immobilization method based on electron beam irradiation was investigated, which allows much faster, cleaner, and cheaper fabrication of enzyme membrane reactors. Two industrial lipase enzymes were coupled onto a polyvinylidene fluoride (PVDF) flat sheet membrane to create self-cleaning surfaces. The response surface methodology (RSM) in the design-of-experiments approach was applied to investigate the effects of three numerical factors on enzyme activity, yielding a maximum activity of 823 ± 118 U m−2 (enzyme concentration: 8.4 g L−1, impregnation time: 5 min, irradiation dose: 80 kGy). The lipolytic membranes were used in fouling tests with olive oil (1 g L−1 in 2 mM sodium dodecyl sulfate), resulting in 100% regeneration of filtration performance after 3 h of self-cleaning in an aqueous buffer (pH 8, 37 °C). Reusability with three consecutive cycles demonstrates regeneration of 95%. Comprehensive membrane characterization was performed by determining enzyme kinetic parameters, permeance monitoring, X-ray photoelectron spectroscopy, FTIR spectroscopy, scanning electron microscopy, and zeta potential, as well as water contact angle measurements.
Negatively Charged MOF-Based Composite Anion Exchange Membrane with High Cation Selectivity and Permeability
Authors: Li Xiaohuan , Afsar Noor Ul , Chen Xiaopeng , Wu Yifeng , Chen Yu , Shao Feng , Song Jiaxian , Yao Shuai , Xia Ru , Qian Jiasheng , Wu Bin , Miao Jibin
Published: June 2022

Every metal and metallurgical industry is associated with the generation of wastewater, influencing the living and non-living environment, which is alarming to environmentalists. The strict regulations about the dismissal of acid and metal into the environment and the increasing emphasis on the recycling/reuse of these effluents after proper remedy have focused the research community’s curiosity in developing distinctive approaches for the recovery of acid and metals from industrial wastewaters. This study reports the synthesis of UiO-66-(COOH)2 using dual ligand in water as a green solvent. Then, the prepared MOF nanoparticles were introduced into the DMAM quaternized QPPO matrix through a straightforward blending approach. Four defect-free UiO-66-(COOH)2/QPPO MMMs were prepared with four different MOF structures. The BET characterization of UiO-66-(COOH)2 nanoparticles with a highly crystalline structure and sub-nanometer pore size (~7 Å) was confirmed by XRD. Because of the introduction of MOF nanoparticles with an electrostatic interaction and pore size screening effect, a separation coefficient (SHCl/FeCl2) of 565 and UHCl of 0.0089 m·h−1 for U-C(60)/QPPO were perceived when the loading dosage of the MOF content was 10 wt%. The obtained results showed that the prepared defect-free MOF membrane has broad prospects in acid recovery applications.
Plasma Membrane-Associated Proteins Identified in Arabidopsis Wild Type, lbr2-2 and bak1-4 Mutants Treated with LPSs from Pseudomonas syringae and Xanthomonas campestris
Authors: Offor Benedict C. , Mhlongo Msizi I. , Dubery Ian A. , Piater Lizelle A.
Published: June 2022

Plants recognise bacterial microbe-associated molecular patterns (MAMPs) from the environment via plasma membrane (PM)-localised pattern recognition receptor(s) (PRRs). Lipopolysaccharides (LPSs) are known as MAMPs from gram-negative bacteria that are most likely recognised by PRRs and trigger defence responses in plants. The Arabidopsis PRR(s) and/or co-receptor(s) complex for LPS and the associated defence signalling remains elusive. As such, proteomic identification of LPS receptors and/or co-receptor complexes will help to elucidate the molecular mechanisms that underly LPS perception and defence signalling in plants. The Arabidopsis LPS-binding protein (LBP) and bactericidal/permeability-increasing protein (BPI)-related-2 (LBR2) have been shown to recognise LPS and trigger defence responses while brassinosteroid insensitive 1 (BRI1)-associated receptor kinase 1 (BAK1) acts as a co-receptor for several PRRs. In this study, Arabidopsis wild type (WT) and T-DNA knock out mutants (lbr2-2 and bak1-4) were treated with LPS chemotypes from Pseudomonas syringae pv. tomato DC3000 (Pst) and Xanthomonas campestris pv. campestris 8004 (Xcc) over a 24 h period. The PM-associated protein fractions were separated by liquid chromatography and analysed by tandem mass spectrometry (LC-MS/MS) followed by data analysis using ByonicTM software. Using Gene Ontology (GO) for molecular function and biological processes, significant LPS-responsive proteins were grouped according to defence and stress response, perception and signalling, membrane transport and trafficking, metabolic processes and others. Venn diagrams demarcated the MAMP-responsive proteins that were common and distinct to the WT and mutant lines following treatment with the two LPS chemotypes, suggesting contributions from differential LPS sub-structural moieties and involvement of LBR2 and BAK1 in the LPS-induced MAMP-triggered immunity (MTI). Moreover, the identification of RLKs and RLPs that participate in other bacterial and fungal MAMP signalling proposes the involvement of more than one receptor and/or co-receptor for LPS perception as well as signalling in Arabidopsis defence responses.
Enhancing Performance of Thin-Film Nanocomposite Membranes by Embedding in Situ Silica Nanoparticles
Authors: De Guzman Manuel Reyes , Ang Micah Belle Marie Yap , Hsu Kai-Ting , Chu Min-Yi , Millare Jeremiah C. , Huang Shu-Hsien , Tsai Hui-An , Lee Kueir-Rarn
Published: June 2022

In this work, silica nanoparticles were produced in situ, to be embedded eventually in the polyamide layer formed during interfacial polymerization for fabricating thin-film nanocomposite membranes with enhanced performance for dehydrating isopropanol solution. The nanoparticles were synthesized through a sol-gel reaction between 3-aminopropyltrimethoxysilane (APTMOS) and 1,3-cyclohexanediamine (CHDA). Two monomers—CHDA (with APTMOS) and trimesoyl chloride—were reacted on a hydrolyzed polyacrylonitrile (hPAN) support. To obtain optimum fabricating conditions, the ratio of APTMOS to CHDA and reaction time were varied. Field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) were used to illustrate the change in morphology as a result of embedding silica nanoparticles. The optimal conditions for preparing the nanocomposite membrane turned out to be 0.15 (g/g) APTMOS/CHDA and 60 min mixing of APTMOS and CHDA, leading to the following membrane performance: flux = 1071 ± 79 g∙m−2∙h−1, water concentration in permeate = 97.34 ± 0.61%, and separation factor = 85.39. A stable performance was shown by the membrane under different operating conditions, where the water concentration in permeate was more than 90 wt%. Therefore, the embedment of silica nanoparticles generated in situ enhanced the separation efficiency of the membrane.
Chemical Vapour Deposition Graphene–PMMA Nanolaminates for Flexible Gas Barrier
Authors: Baldanza Antonio , Pastore Carbone Maria Giovanna , Brondi Cosimo , Manikas Anastasios C. , Mensitieri Giuseppe , Pavlou Christos , Scherillo Giuseppe , Galiotis Costas
Published: June 2022

Successful ways of fully exploiting the excellent structural and multifunctional performance of graphene and related materials are of great scientific and technological interest. New opportunities are provided by the fabrication of a novel class of nanocomposites with a nanolaminate architecture. In this work, by using the iterative lift-off/float-on process combined with wet depositions, we incorporated cm-size graphene monolayers produced via Chemical Vapour Deposition into a poly (methyl methacrylate) (PMMA) matrix with a controlled, alternate-layered structure. The produced nanolaminate shows a significant improvement in mechanical properties, with enhanced stiffness, strength and toughness, with the addition of only 0.06 vol% of graphene. Furthermore, oxygen and carbon dioxide permeability measurements performed at different relative humidity levels, reveal that the addition of graphene leads to significant reduction of permeability, compared to neat PMMA. Overall, we demonstrate that the produced graphene–PMMA nanolaminate surpasses, in terms of gas barrier properties, the traditional discontinuous graphene–particle composites with a similar filler content. Moreover, we found that the gas permeability through the nanocomposites departs from a monotonic decrease as a function of relative humidity, which is instead evident in the case of the pure PMMA nanolaminate. This work suggests the possible use of Chemical Vapour Deposition graphene–polymer nanolaminates as a flexible gas barrier, thus enlarging the spectrum of applications for this novel material.
Evolution and Evaluation of Aesthetic Properties in Weathering Steel Accelerated Patinas: The Role of Lepidocrocite
Authors: Crespo Ana , Pérez Gloria , Jiménez José A. , Llorente Irene , Martínez-Ramírez Sagrario , Cano Emilio , Díaz Iván
Published: June 2022

Weathering steels are widely used in civil engineering, architecture and contemporary art due to their mechanical properties, their enhanced resistance to atmospheric corrosion as well as their aesthetic properties. Artists and blacksmiths often apply chemical treatments to obtain the appealing colors of a patina in a shorter period of time. However, the development of an accelerated patina may have an effect on the final appearance and color of the surface. With the aim of evaluating differences in color and studying the evolution of the surface, eight accelerated patinas were made and exposed to the atmosphere for periods of time of up to 24 months and were compared to a natural patina. The characterization studies showed the presence of lepidocrocite on the surface. A close inspection of the X-ray diffraction patterns showed the displacement of the (020) lepidocrocite reflection and asymmetric broadening of selective lines of this phase that were associated to stacking and twins faults, respectively. These faults decrease with the exposure time and are related to a maximum at 630 nm in the reflectance spectrum and the stabilization of the b* coordinate (yellow color). The colors of the accelerated patinas differ from the natural patina at short exposure times. However, they tend to converge at longer exposure times.
Numerical Study on Asymmetrical Rolled Aluminum Alloy Sheets Using the Visco-Plastic Self-Consistent (VPSC) Method
Authors: Graça Ana , Vincze Gabriela , Wen Wei , Butuc Marilena C. , Lopes Augusto B.
Published: June 2022

Asymmetric rolling is a forming process that has raised interest among researchers due to the significant improvements it introduces to the mechanical response of metals. The main objective of the present work is to perform a numerical study on asymmetrical rolled aluminum alloy sheets to identify and correlate the effect of the additional shear strain component on the material formability, tensile strength, and texture orientations development during multi-pass metal forming. Conventional (CR), asymmetric continuous (ASR-C), and asymmetric rolling-reverse (ASR-R) simulations were carried out using the visco-plastic self-consistent (VPSC) code. For the ASR process, two different shear strain values were prescribed. Moreover, two hardening models were considered: a Voce-type law and a dislocation-based model that accounts for strain path changes during metal forming. Results showed that the ASR process is able to improve the plastic strain ratio and tensile strength. The ASR-C revealed better results, although the expected shear orientations are only evident in the ASR-R process.
Experimental Determination of the Conversion Rate of Molten White Metal by Supplying Individual Air Bubbles
Authors: Roa-Jofré Maximiliano F. , Parra-Sánchez Víctor R. , Reyes-Alcántara Gonzalo A. , Araneda-Hernández Eugenia A. , Balladares-Varela Eduardo R. , Parra-Figueroa Roberto A. , Mora-Vilches Camila V.
Published: June 2022

The conversion of copper sulfide mattes lacks fundamental kinetic information for understanding the process. This work presents the results of the experimental measurement of the rate of oxidation of molten white metal by supplying individual air bubbles. The bubbles were characterized from information collected during the experiments and through theoretical and empirical correlations. Conversion tests were carried out at different temperature conditions and injection dynamics of the oxidizing gas. The results indicate that the conversion is controlled by the transport of oxygen into the bubble. A dependency between the characteristics of the injector and the shape, size and surface of the bubbles was identified. The oxidation rate of the white metal depended on the characteristics of the bubbles and the oxygen available for conversion. The results of this research provide relevant information to improve the operation of industrial conversion furnaces by controlling gas injection through the tuyeres. The criterion for improving conversion systems is the balance between the retention of the bubbles in the molten white metal and their size, such that the availability of oxygen for the conversion is guaranteed.
Effect of Grain Orientation on Hydrogen Embrittlement Behavior of Interstitial-Free Steel
Authors: Wang Wei , Fu Hao , Zhang Hailong , Yan Yu , Li Jinxu
Published: June 2022

In interstitial-free (IF) steel with a certain microtexture, the micro-orientation of grains is essential to understand the occurrence of hydrogen-induced cracking in body-centered cubic (BCC) structural steels. In this study, the hydrogen embrittlement (HE) susceptibility of IF steels was determined by slow strain rate tensile (SSRT) tests and hydrogen microprinting (HMT) experiments from the perspective of crystal orientation. The strength of the specimen with hydrogen was slightly higher than that without hydrogen, while the ductility and toughness were drastically reduced by hydrogen charging during the SSRT test. The HE susceptibility was characterized by the loss of elongation (Iδ) and toughness (Iψ), with losses of 46.3% and 70%, respectively. The microstructural observations indicate that cracks initiated along grains oriented in the {100} || normal direction (ND), and grain boundaries (GBs) around {100}||ND were prone to be enriched in hydrogen atoms; that is, {100} || ND showed poor resistance to intergranular cracking and susceptible to hydrogen segregation. HMT was used to confirm the above viewpoints. Meanwhile, the statistical results showed those high-angle misorientations of 50–60° deviation are the locations most vulnerable to fracture.
Effect of Two-Step High Temperature Treatment on Phase Transformation and Microstructure of V-Bearing Bainitic Steel
Authors: Lv Bo , Yin Dongxin , Sun Dongyun , Yang Zhinan , Long Xiaoyan , Liu Zeliang
Published: June 2022

The effects of VC precipitation on phase transformation, microstructure, and mechanical properties were studied by controlling two-step isothermal treatment, i.e., austenization followed by intercritical transformation. The results show that the bainite transformation time of 950 °C–860 °C treatment and 950 °C–848 °C treatment is shorter than that of 950 °C single-step treatment. This is related to the isothermal ferrite transformation in the intercritical transformation range. The formation of ferrite nuclei increases the density of medium temperature bainite nucleation sites and decrease the bainite nucleation activation energy. At the same time, a large number of VC particles are precipitated. The additional VC particles provide numbers of preferential nucleation sites. The toughness of the specimen treated at 950~870 °C is improved, which is related to the large proportion of high angle grain boundaries. High angle grain boundaries can hinder crack propagation or change the direction of crack propagation. The specimen treated at 950 °C–848 °C exhibits large proportion of low angle grain boundaries, which is beneficial for the strength improvement.
Reinforcement of Tooling Using Residual Stresses Generated by Cladding by Arc Welding
Authors: Israr Rameez , Buhl Johannes , Härtel Sebastian , Bambach Markus
Published: June 2022

Cladding is typically used to protect components from wear and corrosion while also improving the aesthetic value and reliability of the substrate. The cladding process induces significant residual stresses due to the temperature difference between the substrate and the clad layer. However, these residual stresses could be effectively utilized by modifying processes and geometrical parameters. This paper introduces a novel methodology for using the weld-cladding process as a cost-effective alternative to various existing reinforcement techniques. The numerical analyses are performed to maximize the reinforcement of a cylindrical tool. The investigation of how the weld cladding develops compressive stresses on the specimen in response to a change in the weld beads and the welding sequence is presented. For the benchmark shape, experimental verification of the numerical model is performed. The influence of the distance between the weld beads and the effect of the tool diameter is numerically investigated. Furthermore, the variation in compressive stresses due to temperature fluctuations during the extrusion process has been evaluated. The results showed that adequate compressive stresses are generated on the welded parts through the cladding process after cooling. More compressive stresses are induced in the tool as the cross-section of the weld bead is increased. Furthermore, keeping a gap between the adjacent beads improves tool reinforcement. Hence, the targeted reinforcement of the substrate can be achieved by optimizing the welding sequence and process parameters.
The Benefit of the Process Combination of Wire Arc Additive Manufacturing (WAAM) and Forming—A Numerical and Experimental Study
Authors: Sydow Benjamin , Jhanji Avantika , Hälsig André , Buhl Johannes , Härtel Sebastian
Published: June 2022

Wire arc additive manufacturing (WAAM) involves the deposition of weld beads layer by layer using an electric arc energy source. However, during this procedure, the properties of each layer may differ because of unequal thermal distribution, resulting in a difference in microstructure and, therefore, mechanical properties in between the layers. This negative effect can be compensated for by combining WAAM with a subsequent forming process to introduce dynamic recrystallization, which allows a more homogeneous microstructure distribution within the material. This paper investigates numerically and experimentally the hybrid process of combined WAAM and forming of fine-grained mild steel (FGMS) SG3/G4Si (1.5130) to achieve a high degree of recrystallization in all layers of the WAAM-deposited material. Three different possible combinations of WAAM and forming are considered regarding the sequence and setup of the processes to show their influences on the recrystallization behavior. It was found that combining welding and forming allows recrystallization of up to two layers; however, the top layer is not recrystallized. Preliminary simulation results show that this can be resolved by adding a top roller to induce plastic strain after welding, leading to recrystallization in the top layer. The found results promise a certain controllability of the recrystallization behavior.
Influence of Tungsten Nanoparticles on Microstructure and Mechanical Properties of an Al-5%Mg Alloy Produced by Casting
Authors: Khrustalyov Anton , Kakhidze Nikolay , Platov Vladimir , Zhukov Ilya , Vorozhtsov Alexander
Published: June 2022

This paper investigates the impact of tungsten nanoparticles on the microstructure and mechanical properties of the Al-5Mg alloy. Tungsten concentrations of up to 0.5 wt.% led to a slight modification of the Al-5Mg alloy microstructure, and grain refinement occurred due to the inhibition of crystal growth along the boundaries. Dispersion hardening with tungsten nanoparticles made it possible to increase the ultimate strength by the Orowan mechanism with a simultaneous increase in the plasticity of the Al-5Mg alloy. An increase in the tungsten content to 0.8 wt.% made it possible to modify the microstructure of the Al-5Mg alloy, due to the formation of the Al12W phase and an increase in crystallisation centres. The modification of the microstructure, as well as dispersion strengthening by nanoparticles, led to a simultaneous increase in the yield strength, ultimate tensile strength, and ductility of the Al-5Mg alloy.
Synthesizing of Metallized Acrylic Containing Both Gadolinium and Lead as a Transparent Radiation Shielding Material and Its Physical Properties
Authors: Zhang Bo , Wang Fang , Liu Yanke , Yu Haoyu , Zeng Yuansong , Lang Lihui
Published: June 2022

In this study, a series of optically transparent metallized acrylics containing Gd and Pb were synthesized by the bulk polymerization of Gd(MAA)3, Pb(MAA)2 and AM according to different polymerization procedures. The variation of their optic transmittance and mechanical performance with Gd contents was investigated. Then, quasi-static uniaxial tensile tests under different strain rates and temperatures were performed to study the influence of strain rate and temperature on the mechanical properties of radiation-shielding metallized acrylic containing both Gd and Pb. The tensile responses of this material distinctly exhibit nonlinear characteristics and strongly depend on both temperature and strain rate. Based on the experimental results, a modified Zhu–Wang–Tang (ZWT) constitutive model, in which the standard elastic component was replaced by the Mooney–Rivlin hyperelastic model, was implemented to characterize the observed both hyperelastic and viscoelastic behaviors. The constitutive parameters were expressed as functions of temperature and determined by experimental data. The model fitting results indicate that the selected constitutive model can accurately describe the nonlinear tensile stress–strain responses of metallized acrylic containing Gd and Pb. Furthermore, the great difference in constitutive parameters implies that the viscoelastic behavior of the as-prepared metallized acrylic affects the response to quasi-static tensile loading the most.
Study on the Effect of A/B Site Co-Doping on the Oxygen Evolution Reaction Performance of Strontium Cobaltite
Authors: Song Shihao , Mu Xiaoming , Ren Yanwei , Guo Jia , Wei Haifei , Liu Heyan , Lu Zunming
Published: June 2022

The perovskite oxide SrCoO3−x is a promising oxygen electrocatalyst for renewable energy storage and conversion technologies. Here, A, B-site Co-doped perovskite Sr0.5Ba0.5Co0.95Mn0.05O3−x nanoparticles were rationally designed and synthesized by the sol-gel method with an average size of 30–40 nm. It has a remarkable intrinsical activity and stability in 1 M KOH solution. Compared with other A-site (SraA1−aCoO3−x A=Ba, Ca) and B-site doped perovskite (SrCobR1−bO3−x R=Mn, Fe, Ni, B) catalysts, Sr0.5Ba0.5Co0.95Mn0.05O3−x exhibits superior oxygen evolution reaction (OER) performance, smaller Tafel slope, and lower overpotential. The high electrochemical performance of Sr0.5Ba0.5Co0.95Mn0.05O3−x is attributed to its optimized crystal structure and the increase in the content of Co3+. This study demonstrates that highly symmetrical cubic perovskite structure catalytic displays better OER performance.
Global Droplet Heat Transfer in Oxygen Steelmaking Process
Authors: Madhavan Nirmal , Brooks Geoffrey A. , Rhamdhani M. Akbar , Rout Bapin K. , Overbosch Aart
Published: June 2022

Generated droplets in a basic oxygen furnace (BOF) process create an interfacial area between metal and slag/emulsion that helps in heat transfer during different stages of the blowing period. Previous studies have developed extensive models to understand bloating behavior and overall refining kinetics contributed by the droplets in a BOF process. Except for the recent study on single droplet heat transfer by the current authors, no studies in the open literature have addressed the heat transfer contributed by droplets in a BOF. The present work is an extension of single droplet heat transfer, wherein a global droplet heat transfer model is developed by integrating kinetic and dynamic aspects of generated droplets during the blowing period. The model was developed based on previous chemical kinetic studies and input values from plant trials. The results from the global droplet heat transfer model are integrated into the overall zone heat balance calculations to predict the temperature evolution profile of hot spot, slag, and hot metal zones during the blowing period. The results highlight that the hot spot temperature ranges from 1900 °C to 2090 °C, with a peak value of around 2300 °C observed during the middle of the blow. Furthermore, computing the overall droplet heat transfer efficiency, it was observed that the droplets transfer 90% of the heat to the slag up to the first 10 min of the blow, and then the heat transfer efficiency drops towards the end of the blow.
The Effect of Temperature and Phase Shift on the Thermomechanical Fatigue of Nickel-Based Superalloy
Authors: Šulák Ivo , Hrbáček Karel , Obrtlík Karel
Published: June 2022

In this paper, the minimum temperature and phase shift effects on the thermo–mechanical fatigue (TMF) behavior of Inconel 713LC are investigated. TMF tests were performed under 0° (in-phase-IP) and +180° (out-of-phase-OP) phase shifts between mechanical strain and temperature. Cylindrical specimens were cycled at constant mechanical strain amplitude with a strain ratio of Rε = −1. Tests were performed with temperature ranges of 300–900 °C and 500–900 °C. The heating and cooling rate was 5 °C/s. Fatigue hardening/softening curves and fatigue life data were assessed. Results show that out-of-phase loading was less damaging than in-phase loading. Scanning electron microscopy (SEM) examination of metallographic sections indicated that the life-reducing damage mechanism was intergranular cavitation under in-phase loading. Transmission electron microscopy (TEM) revealed honeycomb structures for IP loading. The plastic strain localization into persistent slip bands was typical for OP loading. For out-of-phase loading, fatigue damage appeared to be dominant. The increase in the temperature range led to a significant decrease in fatigue life. The reduction of fatigue life was far more pronounced for out-of-phase loading. This can be ascribed to the accelerated crack propagation at high tensile stress under out-of-phase loading as well as the amount of accommodated plastic strain deformation. Based on the SEM scrutiny of metallographic sections and TEM observations of dislocation arrangement, the prevailing damage mechanisms were documented and the lifetime behavior was accordingly discussed.
Comparison of the Internal Fatigue Crack Initiation and Propagation Behavior of a Quenched and Tempered Steel with and without a Thermomechanical Treatment
Authors: Khayatzadeh Amin , Guth Stefan , Heilmaier Martin
Published: June 2022

Previous studies have shown that a thermomechanical treatment (TMT) consisting of cyclic plastic deformation in the temperature range of dynamic strain aging can increase the fatigue limit of quenched and tempered steels by strengthening the microstructure around non-metallic inclusions. This study considers the influence of a TMT on the shape, size and position of crack-initiating inclusions as well as on the internal crack propagation behavior. For this, high cycle fatigue tests on specimens with and without TMT were performed at room temperature at a constant stress amplitude. The TMT increased the average lifetime by about 40%, while there was no effect of the TMT on the form or size of critical inclusions. Surprisingly, no correlation between inclusion size and lifetime could be found for both specimen types. There is also no correlation between inclusion depth and lifetime, which means that the crack propagation stage covers only a small portion of the overall lifetime. The average depth of critical inclusions is considerably higher for TMT specimens indicating that the strengthening effect of the TMT is more pronounced for near-surface inclusions. Fisheye fracture surfaces around the critical inclusions could be found on all tested specimens. With increasing fisheye size, a transition from a smooth to a rather rough and wavy fracture surface could be observed for both specimen types.
Effect of Batch Dissimilarity on Permeability of Stacked Ceramic Foam Filters and Incompressible Fluid Flow: Experimental and Numerical Investigation
Authors: Akbarnejad Shahin , Tilliander Anders , Sheng Dong-Yuan , Jönsson Pär Göran
Published: June 2022

Ceramic foam filters (CFFs) are used to remove inclusions and/or solid particles from molten metal. In general, the molten metal poured on the top of a CFF should reach a certain height to form the pressure (metal head) required to prime the filter. For estimating the required metal head and obtaining the permeability coefficients of the CFFs, permeability experiments are essential. Recently, electromagnetic priming and filtration of molten aluminum with low and high grades of CFF, i.e., 30, 50 and 80 pore per inch (PPI) CFFs, have been introduced. Since then, there has been interest in exploring the possibility of obtaining further inclusion entrapment and aluminum refinement by using electromagnetic force to prime and filter with stacked CFFs. The successful execution of such trials requires a profound understanding concerning the permeability parameters of the stacked filters. Such data were deemed not to exist prior to this study. As a result, this study presents experimental findings of permeability measurements for stacks of three 30, three 50 and three 80 PPI commercial alumina CFFs from different industrial batches and compares the findings to numerically modelled data as well as previous research works. Both experimental and numerical findings showed a good agreement with previous results. The deviation between the experimentally and numerically obtained data lies in the range of 0.4 to 6.3%.
Biofilm Development on Carbon Steel by Iron Reducing Bacterium Shewanella putrefaciens and Their Role in Corrosion
Authors: Welikala Sachie , Al-Saadi Saad , Gates Will P. , Panter Christopher , Raman R. K. Singh
Published: June 2022

Microscopic, electrochemical and surface characterization techniques were used to investigate the effects of iron reducing bacteria (IRB) biofilm on carbon steel corrosion for 72 and 168 h under batch conditions. The organic nutrient availability for the bacteria was varied to evaluate biofilms formed under nutritionally rich, as compared to nutritionally deficient, conditions. Focused ion beam-scanning electron microscopy (FIB-SEM) was used to investigate the effect of subsurface biofilm structures on the corrosion characteristics of carbon steel. Hydrated biofilms produced by IRB were observed under environmental scanning electron microscope (ESEM) with minimal surface preparation, and the elemental composition of the biofilms was investigated using energy dispersive spectroscopy (EDX). Attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) was used to provide information on the organic and inorganic chemical makeup of the biofilms. Electrochemical techniques employed for assessing corrosion, by open circuit potential, linear polarization and potentiodynamic polarization tests indicated no significant difference in the corrosion resistance for carbon steel in IRB-inoculated, compared to the abiotic solutions of common Postgate C after 72 and 168 h. However, the steel was found to be more susceptible to corrosion when the yeast extract was removed from the biotic environment for the 168 h test. In the absence of yeast nutrient, it is postulated that IRB received energy by transforming the protective film of Fe3+ into more soluble Fe2+ products.
An Improved Method to Quantify Short-Chain Fatty Acids in Biological Samples Using Gas Chromatography–Mass Spectrometry
Authors: Kim Kyeong-Seog , Lee Yujin , Chae Woori , Cho Joo-Youn
Published: June 2022

Gut microbial metabolites, short-chain fatty acids (SCFAs), are found at multiple locations in the host body and are identified as important metabolites in gut microbiome-associated diseases. Quantifying SCFAs in diverse biological samples is important to understand their roles in host health. This study developed an accurate SCFA quantification method by performing gas chromatography–mass spectrometry (GC/MS) in human plasma, serum, feces, and mouse cecum tissue. The samples were acidified with hydrochloric acid, and the SCFAs were extracted using methyl tert-butyl ether. In this method, distilled water was selected as a surrogate matrix for the quantification of SCFAs in target biological samples. The method was validated in terms of linearity, parallelism, precision, recovery, and matrix effect. The developed method was further applied in target biological samples. In conclusion, this optimized method can be used as a simultaneous SCFA quantification method in diverse biological samples.
Alterations in Blood Plasma Metabolome of Patients with Lesniowski-Crohn’s Disease Shortly after Surgical Treatment—Pilot Study
Authors: Idkowiak Jakub , Kubiak-Tomaszewska Grażyna , Gątarek Paulina , Marczak Łukasz , Kałużna-Czaplińska Joanna , Tarnowski Wiesław , Uryszek Mariusz , Bobrowska-Korczak Barbara
Published: June 2022

Lesniowski-Crohn’s disease (CD) is a type of chronic inflammatory bowel disease (IBD) of uncertain etiology. Initially, pharmacological management is undertaken; however, surgical intervention is necessary to improve life quality and relieve symptoms in most cases. Here changes are reported in blood metabolome that occurred three days after the ileo-colic region resection in the case of seven patients. Alterations are observed in levels of metabolites associated with multiple mitochondrial pathways, based on the Metabolite Set Enrichment Analysis, reflecting a high energy demand in the post-operative period. As most of these metabolites are also essential nutrients supplied from foods, we believe that our results might contribute to the discussion on perioperative nutrition’s role in enhanced recovery.
Sea Bass Essence from Lates calcarifer Improves Exercise Performance and Anti-Fatigue in Mice
Authors: Tai Hong-Jun , Lee Mon-Chien , Hsu Yi-Ju , Kuo Chun-Yen , Huang Chi-Chang , Wang Ming-Fu
Published: June 2022

Sea bass (Lates calcarifer) is rich in protein, amino acids, and long-chain omega 3 (omega-3), which have many health benefits. In East Asian food culture, soup is often eaten as a nutritional supplement. The purpose of this study was to investigate the benefits of Hi-Q sea bass essence (SBE) supplementation for improved exercise performance and anti-fatigue. Fifty male Institute of Cancer Research (ICR) mice were divided to five groups (10 mice/group) and administered different doses of SBE (EC): (1) vehicle (water); (2) isocaloric (0.94 g casein/kg/mice/day); (3) SBE-1X (1.04 g/kg/mice/day); (4) SBE-2X (2.08 g/kg/mice/day); and (5) SBE-4X (4.16 g/kg/mice/day). We found that SBE supplementation significantly improved more than 1.96-fold endurance exercise performance (p < 0.05) and more than 1.13-fold glycogen storage in the liver and muscles (p < 0.05), and had dose-dependent by SBE dose (p < 0.05). In addition, supplementation with SBE at different doses had significant effects on the fatigue-related biochemical markers, i.e., lactate, ammonia, and blood urea nitrogen (BUN) levels were reduced significantly (p < 0.05), and were also dose-dependent. In conclusion, supplementation with SBE for 4 weeks was able to effectively improve exercise performance and had an anti-fatigue effect. In addition, it did not cause any physiological or histopathological damage.
Urine and Fecal 1H-NMR Metabolomes Differ Significantly between Pre-Term and Full-Term Born Physically Fit Healthy Adult Males
Authors: Deutsch Leon , Debevec Tadej , Millet Gregoire P. , Osredkar Damjan , Opara Simona , Šket Robert , Murovec Boštjan , Mramor Minca , Plavec Janez , Stres Blaz
Published: June 2022

Preterm birth (before 37 weeks gestation) accounts for ~10% of births worldwide and remains one of the leading causes of death in children under 5 years of age. Preterm born adults have been consistently shown to be at an increased risk for chronic disorders including cardiovascular, endocrine/metabolic, respiratory, renal, neurologic, and psychiatric disorders that result in increased death risk. Oxidative stress was shown to be an important risk factor for hypertension, metabolic syndrome and lung disease (reduced pulmonary function, long-term obstructive pulmonary disease, respiratory infections, and sleep disturbances). The aim of this study was to explore the differences between preterm and full-term male participants’ levels of urine and fecal proton nuclear magnetic resonance (1H-NMR) metabolomes, during rest and exercise in normoxia and hypoxia and to assess general differences in human gut-microbiomes through metagenomics at the level of taxonomy, diversity, functional genes, enzymatic reactions, metabolic pathways and predicted gut metabolites. Significant differences existed between the two groups based on the analysis of 1H-NMR urine and fecal metabolomes and their respective metabolic pathways, enabling the elucidation of a complex set of microbiome related metabolic biomarkers, supporting the idea of distinct host-microbiome interactions between the two groups and enabling the efficient classification of samples; however, this could not be directed to specific taxonomic characteristics.
Controllable Shrinking Fabrication of Solid-State Nanopores
Authors: Lei Xin , Zhang Jiayan , Hong Hao , Yuan Zhishan , Liu Zewen
Published: June 2022

Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy. Despite the most use of naturally biological nanopores before, solid-state nanopores are widely developed with strong robustness, controllable sizes and geometries, a wide range of materials available, as well as flexible manufacturing. Therefore, various techniques typically based on focused ion beam or electron beam have been explored to drill nanopores directly on free-standing nanofilms. To further reduce and sculpt the pore size and shape for nano or sub-nano space-time sensing precision, various controllable shrinking technologies have been employed. Correspondingly, high-energy-beam-induced contraction with direct visual feedback represents the most widely used. The ability to change the pore diameter was attributed to surface tension induced original material migration into the nanopore center or new material deposition on the nanopore surface. This paper reviews typical solid-state nanopore shrinkage technologies, based on the careful summary of their principles and characteristics in particularly size and morphology changes. Furthermore, the advantages and disadvantages of different methods have also been compared completely. Finally, this review concludes with an optimistic outlook on the future of solid-state nanopores.