bluuebunny/crossref_metadata_2025 huggingface dataset:
Design of a Model to Structure Longitudinal Data for Medical Education Based on the I-E-O Model
Authors: Jung Hanna , Lee I Re , Kim Hae Won , An Shinki
Published: March 2023

The purpose of this study was to establish a model for constructing longitudinal data for medical school, and to structure cohort and longitudinal data using data from Yonsei University College of Medicine (YUCM) according to the established input-environment-output (I-E-O) model. The study was conducted according to the following procedure. First, the data that YUCM has collected was reviewed through data analysis and interviews with the person in charge of each questionnaire. Second, the opinions of experts on the validity of the I-E-O model were collected through the first expert consultation, and as a result, a model was established for each stage of medical education based on the I-E-O model. Finally, in order to further materialize and refine the previously established model for each stage of medical education, secondary expert consultation was conducted. As a result, the survey areas and time period for collecting longitudinal data were organized according to the model for each stage of medical education, and an example of the YUCM cohort constructed according to the established model for each stage of medical education was presented. The results derived from this study constitute a basic step toward building data from universities in longitudinal form, and if longitudinal data are actually constructed through this method, they could be used as an important basis for determining major policies or reorganizing the curricula of universities. These research results have implications in terms of the management and utilization of existing survey data, the composition of cohorts, and longitudinal studies for many medical schools that are conducting surveys in various areas targeting students, such as lecture evaluation and satisfaction surveys.
Sistema de categorías para el estudio de la eficacia escolar v2
Authors: Ortiz-de-Villate Carla
Published: March 2023

Sistema de categorías para el estudio de la eficacia escolar. Se ha calculado su confiabilidad y concordancia entre investigadores en nuestra investigación con un alfa de Krippendorff alto (α=0.807).
The Syrian stratum of the Ukrainian toponymics (the Byzantine time)
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, TYSHCHENKO K.
Published: March 2023

The article highlights the important consequences of reliable identification of the group of place names Zhabye as replicas of the prototype Jābiya – the capital of the Ghassanid (Byzantine federates in the VI–VII century). Thanks to this, it became possible to systematize already studied Ukrainian replicas of the Byzantine age names-prototypes from Syria. Among the selected prototypes in the Middle East are: toponyms 'Asqalan, Callinicum / Raqqa, Dimashq Damascus, Fihl, Halab, ḤAWRĀN, Jābiya, Jarash, JIBAL, Quds = Bayt al-Maqdis Jerusalem, Laodicaea/ Ladhiq, Palmyra, PHOENICIA, Ruṣāfa/ Sergiopolis / Ῥάφες, Tiberias, Tripolis, Bilad al-SHAM / SURIYEH Syria, Yathrib/ Medina; anthroponyms Theodosius, Ya'qūbī Jacob Baradaeus. As of 2019, highly reliable replicas of these prototypes were discovered in Ukraine: Oskolonivka, Skalonivka, Kalynuvatka, Kalynivka (over 80 place names), Raky, Rachyntsi, Damasky, Demeshkivtsi, Fyholivka, Khalepya, Khaleptsi, Tverdokhliby (3), Havrontsi, Havronshchyna, Zhabelivka, group Zhabye (20), Yaroshi (4), Yaroshivka (4), Yaryshiv, Chepelivka, group Kutsivka, Mahdyn, Ladyzhyn (6), Pal'myrivka, Ponykva, Ponykovytsia, Rusava, Rosava (4), Rasavka, Rosokha, Rosokhovatka, Serhiyi, Tyvriv (2), Trypill'a (2), Shamy / Surzha, Surozh, Yastrub- (14), Pedosy, Khodosy, Yakubivka e. a. The first replicas of this vector (Tripol, Khalep, Korsun') were pointed out by V. Z. Zavytnevytch and A. I. Sobolevsky as similar to the Byzantine place names. The remaining synchoric names were identified with varying degrees of reliability by the method of toponymic contextualization in 2008–2019. Moreover, if each individual replica can be challenged, their mutual conditionality acquires a new scientific quality (V. I. Abaev). The current find of the initial territory with a concentration of synchoric and synchronous prototypes of this vector of toponyms-replicas in Ukraine radically improves scientific ideas about the whole picture of contacts between the steppe and forest-steppe population of the Dnieper region with Byzantium in the pre-chronicle time (IV–IX centuries).
The role of Andaluzian poetry in the formation and development of the lyrics of the Provencal troubadours
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, VELYCHKO M. , BRATEL O. ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: March 2023

In the review article the theories of the Arabic origin of West European chivalrous poetry were analyzed. The article deals with the problem of the direct interaction between Arabic and European literary traditions, in particular, the probability of the impact of the Arab-Spanish strophic poetry on Provencal troubadour's lyrics and the possibility of the influence of Andalusian poetry on Spanish and Provencal. So that it is established that al-Andalus was a multilingual society in which the Andalusi Romance dialects were spoken and written alongside Arabic. In Europe, and from scholars working in departments of modern national languages, this usually means the discussion of what it means to write in Middle English, or German, or French instead of Latin. The Andalusian poets could easily convey in Romance the motives and themes inherent in Arabic classical literature, and with the help of the Arabic language they expressed elements of Roman folk poetry. The analysis of various researches showed that the issue of the historical and geographical formation and development of Arab-Spanish poetry during the Middle Ages were studied by Arab and European sceintists of past centuries, as well as by the modern literary scientists. Modern studies of the Arab-Spanish medieval stanza do not deny the existence of an interaction between European and Arabic lyrics, but the role of this interaction on the scale of the history of world literature remains unclear. Lyrics of the troubadours of the 11th–14th centuries was a unique synthesis of many literary elements of church Latin poetry, folk poetry and Arab influences, and strongly influenced on the history of Italian, Spanish, English, Portuguese, German literature.
Types of poetry figures (shabdalankar) of Mira Bai's poetry
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, DOVBNYA K.
Published: March 2023

This article addresses the issue of the types of poetic figures (shabdalankar) in the poetry of the famous poetess of the medieval socio-religious movement bhakti Mira Bai, namely, an important category of Hindi poetry – alankars, which help to express aesthetic emotion – racu. Therefore, their study is of great importance for characterizing the work of Mira Bai in general. Alankars are usually called rhetorical figures, and their close translation – "decorations" – corresponds to the most important European rhetorical category fully, which covers the concept of figures and paths ornatus. They adorn the sound and meaning of the word and help to show aesthetic emotion – racu. It was suggested to study the types of shabdalankar (form decorations) in the poetry of Mira Bai. It was reviewed such shabdalankars as anupras (alliteration), yamaka (lexical repetition – "consonance"), vacrocti and shlesha (some types of paronomasia – "combination"). It was found that in the verses of Mira Bai there are mainly two of them – anupras and vipsa. A feature of the formal side of Mira Bai's works is miserly use of poetry adornments, since the poetry's verses are a cry of the soul, they reflect the unbearable pain of separation from her beloved Krishna. In such a state of mind, Mira Bai was not up to artificial decoration and play on words. If individual alancars appear in her poetry, it happens completely at ease. Only one of several shabdalankar dominates in the verses of Mira Bai, namely: anuprasa, which helps the poetess through the melody of the verse to create the mood she needs and clearly show the aesthetic emotion of love – the shringar's racu.
Specificity of revolutionary poetry of Hasan Hoseini
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, LEVCHYN I.
Published: March 2023

The author of this overview article examines the specificity of themes in the revolutionary poetry of Iranian poet Hasan Hoseini (1956–2004) – a representative of the younger generation of poets in 80s of the twentieth century in Iran. The relevance of the chosen topic is due to the insufficient number of Ukrainian-language studies devoted to the poetry of certain figures of Iranian poets of that period and their idostyle, particularly Hasan Hoseini's poetry. His personality as one of the bright creators of revolutionary and post-revolutionary Persian poetry of the late twentieth century in Iran was discovered thanks to revealing the specifics of the thematic content and artistic images of his poetry, which differed in social, patriotic and religious directions. It was revealed that Hassan Hoseini's poetry is filled with the propagation of Shiite religious views, reflections on national justice, responsibility for the fate of the fatherland, and social stratification of people. In his poems, the poet sharply criticizes the negative qualities of man, exalts the leaders of the Islamic Revolution, expresses hope for a better future for the Iranian people, etc. The study of poetry from his collections "Consonant with Ishmael" and "Sparrow and Gabriel" made it possible to identify the main features of the Hasan Hoseini's works such as: the variety of genre forms, among which Masnavi with innovative views and rhymes occupies a special place; new storylines; the prevalence of poetry of sociopolitical nature with religious orientation; transferring images of she'r-e now into the "new ghazal"; an inner melody of words; a large number of artistic means; new complex images and metaphors; the fullness of Iran's rich and high Islamic culture. Having achieved the goal, which was to analyze Iranian Persian-language poetic works of the revolutionary and post-revolutionary periods of the twentieth century and the presentation of their authors to Ukrainian researchers and orientalists, it was possible to defend the value of the Iranian literary heritage of the outlined period with its new facets of Persian literature, its own artistic, aesthetic, ideological and thematic features.
GENOCIDE IN THE HISTORY OF INTERNATIONAL LAW: THE CRIME AND FORMATION OF THE CONCEPT OF THE CRIME
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Butkevych Olga
Published: March 2023

Although the Convention on the Prevention and Punishment of the Crime of Genocide was adopted in 1948, the acts of genocide were known to humankind long before that. Throughout the history, attitudes to mass killings of people in the theory of international law and legal consciousness have been changed. Although these crimes have been known for a long history of international law, the concept of punishment for them has not been shaped uniformly during different epochs. The 19th and early 20th centuries were the period of active development of the idea of genocide as an international crime, however it was finally formed with the adoption of the mentioned Convention.
LEGAL JUSTIFICATION OF FREE WILL AS AN ABSOLUTE RIGHT
Authors:   Karazin Kharkiv National University, Savchenko V.
Published: March 2023

The article provides a legal justification for the absoluteness of free will. The understanding of free will has changed from imagining it as "fatum" in determinism to defining its limitations through international and national legal norms. Suppose the ancient philosophers wrote that God influences a person's will today. In that case, it is considered relevant to understand the limits of free will through the prism of regulatory and legal regulation. This thesis raises the pressing question of whether free will is absolute. The purpose of this article is the legal justification that free will is absolute. To substantiate this thesis, the author proposes to investigate two statements: 1. freedom of will is absolute, and legal norms specify it; 2. freedom of will is not absolute because regulations define its limits. The author examines absolute rights through the prism of their control in international treaties. In particular, an analysis of the normative consolidation and limitation of absolute rights in the International Covenant on Civil and Political Rights, the Convention on the Protection of Human Rights and Fundamental Freedoms, and the Canadian Charter of Rights and Freedoms was carried out. The author analyses the legal grounds for limiting absolute rights. The scientist concludes that the definition of a specific right as absolute is more connected not with the prohibition to limit it but with its significant meaning. It instead characterises absolute rights as natural and inalienable, although not all absolute rights are. The author claims that free will can be considered an absolute right from which other rights arise. The researcher cites an analogy when the absolute right to life gives rise to the right to health care, which gives rise to a whole series of patient rights. As a result, the author emphasises the possibility of assuming that free will is one of the absolute rights from which all others derive. At the same time, it is noted that the possibility of defining freedom of will as a personal non-property right or a principle of law requires a separate study.
Evaluation of In-vitro Anticandidal Activity of 99 Different Commercial Plant Extract, Fixed and Essential Oils against Vaginal Candida albicans Isolates
Authors: ÖZCAN ATEŞ Gülçin , KANBUR Savaş
Published: March 2023

Plant extracts (PE), fixed oils (FO) and essential oils (EO) are used in traditional medicine to treat various diseases. This study evaluated the anticandidal activity of 100 different commercially available PEs, FOs, and EOs against 19 Candida albicans vaginal isolates and C. albicans ATCC 10231. It was determined that 20 EOs and FOs had anticandidal activity. Piper nigrum FO, pine turpentine EO, pine tar EO, and Eugenia caryophyllata EO showed the highest anticandidal activity. The minimum inhibitory concentrations (MIC) and minimum fungicidal concentrations (MFC) values of these FO and EOs were between 0.125 and 2 µL mL-1. The volatile components of these FOs and EOs were determined by GC-MS analysis. There were six components in E. caryophyllata EO, 38 in Pine turpentine EO, 39 in P. nigrum FO, and 119 in Pine tar EO. In conclusion, this FOs and EOs can be used to treat vulvovaginal candidiasis.
La formalización neoliberal en minería. Ruta de precarización de los pequeños mineros en Colombia
Authors: Muñoz-Duque Luz Adriana , Arango-Tobón Mauricio Alexander , Bedoya-Hernández Mauricio Hernando
Published: March 2023

This paper presents the results of a study that aimed to understand the mining formalization process in Colombia as a government strategy; thus, it is based on the reading of policies on this subject as a regime instituted to govern this area of the productive sector in a specific way. This research is qualitative. The methodology was based on symbolic interactions through semi-structured interviews with miners located in two Colombian municipalities in the departments of Antioquia and Caldas. Based on the participants’ statements and some theoretical references, we concluded that the current formalization process has a marked neoliberal component. It has some impacts that spread to the labor sphere and makes the lifestyles of miners, communities, and their families more precarious.
Geological Field Guide of Montes Claros Karst, Minas Gerais
Authors: Cavalcanti José Adilson Dias , Sarmento Ronaldo Lucrécio , Nunes Fredson Reis
Published: March 2023

The Montes Claros Karst is located on the eastern margin of the Bambuí Basin, one of the covers of the São Francisco Craton affected by the Brasiliano Event, which deformed the limestones of the Lagoa do Jacaré Formation, creating a westward folding system and a pair of fractures F1 (NNE-SSW) and F2 (WNW-ESE). These structures control the circulation of water in the limestone massifs, leading to the development of the Montes Claros karst. The main features of the karst landscape are caves, valleys, dolines and limestone massifs. The caves are the best place to observe the main sedimentary facies of the limestones of the Lagoa do Jacaré Formation, as well as sedimentary and deformational structures. The main controls of the cave conduits are the F1 and F2 fractures. These are the same directions described on a regional and local scale, which shows us that the structural control of the exocarst is the same as that of the endocarst. This geological field guide shows in a didactic way the main facies and sedimentary structures of the limestone of the Lagoa do Jacaré Formation, the deformational structures that favoured the karst formation and the typical karst morphologies in limestone rocks.
The Utilization of Memrise in Arabic Language Learning with Blended Learning Method
Authors: Subita Aulia , Ahsanuddin Mohammad
Published: March 2023

Rapid development of technology influences learning process where online learning has replaced the traditional learning. However, because of the numerous problems posed by this transition, the learning process has changed to use blended learning by utilizing technological media. This research aims to describe the utilization of Memrise in Arabic language learning with blended learning method and to describe the obstacles in utilizing Memrise in learning process. This study employs a descriptive qualitative methodology with Miles-Huberman’s data analysis techniques. This study revealed that the process of utilizing Memrise in Arabic language learning using the blended learning method is conducted through several stages, which are preparing the media, face-to-face learning, and online learning. The obstacles in utilizing Memrise in learning process faced by the teacher and students, including inadequate facilities, extra payment for more features and less flexible quizzes.
POLÍTICAS PATRIMONIAIS EM CONFLITO E A MISSÃO DE SÃO MIGUEL ARCANJO (RIO GRANDE DO SUL)
Authors: Dias Adriana Schmidt
Published: March 2023

A partir da década de 1980, a inclusão das ruínas das Missões Guarani na lista Mundial do Patrimônio da UNESCO localizou seu sentido patrimonial em um discurso global. Entre 2004 e 2014, o projeto de registro de São Miguel Arcanjo como Lugar de Referência dos Mbyá-guarani agregou os ‘recém-chegados das margens’ às práticas patrimoniais do IPHAN. Neste processo, porém, o discurso civilizatório não desapareceu, colocando em questão disputas entre distintos regimes de historicidade. O estudo de caso aqui apresentado, levanta a seguinte questão: o que se pode esperar das políticas patrimoniais, além de pensar o passado indígena como experiência do exótico e do fantasmagórico, relacionada ao fetichismo moderno pelas ruínas?
Descenso en la esperanza de vida debido a los homicidios múltiples en México: homicidios de mujeres adyacentes al homicidio de uno o más hombres
Authors: Jasso Vargas Rosalba
Published: March 2023

El objetivo es analizar el efecto de los homicidios múltiples sobre la esperanza de vida para la población masculina y femenina y ofrecer algunas evidencias empíricas sobre la correspondencia temporal y espacial entre las tasas de homicidio de hombres y mujeres, según grupo de edad, durante el periodo 2002-2020. A partir de datos del Instituto Nacional de Estadística y Geografía (INEGI) y de las proyecciones de población del Consejo Nacional de Población (CONAPO), se estimaron las tasas de mortalidad por homicidios en hombres y mujeres entre 2002 y 2020, se analizó la adyacencia de homicidios de hombres y mujeres, la relación espacial entre homicidios múltiples de hombres y mujeres y los cambios en la esperanza de vida debida a homicidios. Los homicidios unipersonales han provocado la mayor pérdida de esperanza de vida de hombres y mujeres. El efecto negativo sobre la esperanza de vida femenina y masculina debida a homicidios múltiples comienza a ser visible a partir de 2008. La exploración de los homicidios de mujeres adyacentes al homicidio de uno o más hombres plantea la inquietud de si estos crímenes son un resultado preponderante de la violencia delincuencial y en menor medida por razones de género.
Ensino da escrita na cultura digital em aulas de Língua Portuguesa durante a Covid-19.
Authors: Signato de Melo Rafael
Published: March 2023

O projeto de pesquisa tem por objetivo geral apresentar as percepções dos professores acerca do ensino da escrita nas aulas de língua portuguesa durante a pandemia visando apresentar algumas reflexões em torno de como os professores precisaram adaptar as atividades para o contexto do ensino remoto em consonância com as habilidades estabelecidas pela Base Nacional Comum Curricular (BNCC). A pesquisa será desenvolvida numa escola pública em Uberaba – MG. Partimos, inicialmente, da seguinte pergunta: como se deu a atividade de produção escrita de textos no período pandêmico e em ensino remoto para o desenvolvimento de atividades em sala de aula? Quais recursos foram utilizados pelos professores para as práticas de escrita? Como os professores analisam esse momento em sua formação enquanto educadores?
trabalho de coordenação pedagógica em instituições públicas de Educação Infantil
Authors: Bezerra Machado Laeda , LOPES FRANÇA ELAINE
Published: March 2023

Este artigo procura caracterizar a atuação da coordenação pedagógica em instituições de  educação infantil, enfatizando seu papel junto à equipe gestora, professores, alunos e famílias dessas instituições. Tratamos conceitualmente coordenação pedagógica, seus aspectos legais e produção cientifica sobre o tema. Desenvolvemos uma pesquisa de abordagem qualitativa, delineada como estudo de campo, com oito coordenadoras que atuam em instituições municipais de educação infantil, situadas no Recife-PE. Os resultados sugerem uma relação de mediação e parceria entre coordenação pedagógica, equipe gestora, docentes, crianças e famílias. No âmbito da coordenação pedagógica detectamos dificuldades para a atuação dessas profissionais em processos de formação continuada de professores dessas instituições.
Análise discursiva de produções de alunos do ensino fundamental
Authors: Procopio Dias Santana Iris
Published: March 2023

O objetivo deste artigo é realizar a análise discursiva das produções de alunos do ensino fundamental para compreender como interpretam os textos que lhes são dados a ler, buscar se há ou não práticas de leitura e escrita regulares em suas produções e finalizar com uma reflexão sobre como os alunos compreendem as práticas de leitura e escrita na escola. As produções aqui analisadas compõem os resultados de minha pesquisa de mestrado para o Profletras da UFTM, foram coletadas durante uma proposta de leitura associada à exploração de múltiplas linguagens que pretendia promover a leitura e a movimentação dos alunos para a escrita. A base teórica para a escrita deste artigo está composta por Possenti (2002), Bakhtin (2003), Geraldi (1997) e Foucault (1988). Após a conclusão das análises foi possível concluir que houve diálogo e movimento dos alunos que leram, interpretaram, posicionaram e deixaram indícios sobre sua constituição subjetiva com indícios autorais.
objetos de aprendizagem no ensino da Matemática
Authors: Ribeiro Resende Marilene , Limírio Brigagão Esder
Published: March 2023

As tecnologias e os ambientes virtuais fazem parte do dia a dia dos nossos alunos e há um esforço para que sejam incorporadas às práticas pedagógicas. No contexto das inovações tecnológicas, surgem, desde o início do século XXI, os chamados Objetos de Aprendizagem (OA), recursos digitais dinâmicos, interativos e reutilizáveis desenvolvidos para fins educacionais. Nesse contexto, este artigo, fruto de pesquisa do tipo “Estado do Conhecimento”, tem o objetivo de mapear trabalhos acadêmicos que tratam o processo ensino-aprendizagem da Matemática com o uso de Objetos de Aprendizagem, no período de 2013 a 2018, na educação básica. Dentre os resultados, pode-se afirmar que esses trabalhos estão sendo realizados, em sua maioria, em mestrados profissionais, com o objetivo de criar e/ou aplicar Objetos de Aprendizagem, ligados a temas de álgebra e geometria, mais voltados para o ensino médio do que para o ensino fundamental. Os OA, segundo os trabalhos selecionados, contribuíram para uma prática pedagógica mais dinâmica, que valoriza os conhecimentos prévios dos alunos, o trabalho coletivo e, principalmente, a investigação. Entretanto, ainda há marcas de visões otimistas, deterministas e instrumentais dos OA, que não se sustentam, sem a consideração das condições objetivas em que as práticas pedagógicas são exercidas.
Formação e trabalho profissional
Authors: Mendes Rita de Cássia Lopes de Oliveira , Malachias Ana Laura
Published: March 2023

A presente pesquisa teve como propósito estudar e conhecer a formação e o trabalho profissional dos egressos do Curso de Graduação em Serviço Social da Universidade Federal do Triângulo Mineiro (UFTM), visando inteirar-se do trabalho dos/as assistentes sociais após sua formação, bem como suas expectativas e percepções, nível de satisfação profissional, empregabilidade. A coleta destas informações permitiu traçar o perfil dos ex-estudantes do curso de Serviço Social da UFTM. A partir de levantamento bibliográfico, pesquisa documental e pesquisa de campo online, com ex-estudantes do curso de Serviço Social, no período de 2013 a 2019, o trabalho traz depoimentos importantes acerca das categorias: vida profissional do/a egresso, formação profissional e formação continuada. A pesquisa poderá subsidiar futuras análises da formação profissional, contribuindo para revisões de Projetos Políticos Pedagógicos do Curso de Serviço Social, bem como devolver à comunidade acadêmica o resultado/visão dos entrevistados na pesquisa sobre sua formação e exercício profissional. Vale ressaltar que a pesquisa é qualitativa e quantitativa e, não tem a pretensão de generalização das respostas.
Management v športu: Izbrana poglavja
Authors: Šprajc Polona
Published: March 2023

Znanstvena monografija Management v športu - izbrana poglavja pokriva področja, ki se prvenstveno nanašajo na področje športa v povezavi z različnimi elementi managementa in upravljanja ter širšimi vidiki družbe. Vsebina monografije je predvsem v koraku s časom in sledi potrebam povezovanja znanstvenih vsebin z aplikativnimi učinki. Poglavja, ki so del znanstvene monografije in obsegajo ustrezno stopnjo interdisciplinarnosti, naj bodo odskočna deska za proučevanje in nadgradnjo znanj študentov, akademske javnosti in širše družbe.
Method for creating a recombinant strain of enterococcus L3-SARS based on biologically active strain Enterococcus faecium L3
Authors: Bormotova E. A. , Gupalova T. V. , Suvorov A. N.
Published: March 2023

The current pandemic caused by the SARS-Cov-2 virus has significantly influenced the emergence of new injectable vaccines that provide a predominantly specific IgG response. However, it is generally accepted that protection against pathogens at the mucosal surface, which is the first barrier to viral entry, is predominantly dependent on the IgA response. It is now widely accepted that the use of genetically modified microorganisms, including probiotics, allows the oral or nasal mucosal delivery of therapeutic molecules, inducing an immune response in the mucous membranes. Probiotic strains are well studied for safety for the organism and are able to remain viable after passing through the gastric barrier, improve intraepithelial connections, and can generate a number of surface expressed molecules that enhance the effectiveness of vaccination.

Recombinant probiotic microorganisms capable of producing vaccine antigens by inserting specific DNA fragments into their genome are one of the potential platforms that can be used to develop an appropriate vaccine containing a specific antigen for rapid response to viral mutations. Here, we demonstrate the construction of a novel SARS-Cov-2 vaccine candidate employing the gene fragment of S1 SARS-Cov-2 gene. According to the available data on new variants of SARS-Cov-2 mutations, three amino acid substitutions were made in the chosen sequence. This DNA fragment was inserted in frame into major pili protein gene within d2 domain of enterococcal operon encoding for pili.
Volatomics in healthcare: technical basis and clinical application
Authors: Silantyev A. S. , Tuter D. S. , Bykova A. A. , Kardonsky D. A. , Betelin V. B. , Chomakhidze P. Sh. , Kopylov P. Yu.
Published: March 2023

Volatilome is a collection of all volatile compounds, both organic and inorganic, the source of which is the object under study. Unlike the metabolome, which includes only compounds of endogenous origin, the concept of volatilome includes substances of both endogenous and exogenous origin. Exhaled air volatilome contains thousands of metabolites and volatile organic compounds (VOCs), which are formed both in the respiratory tract and in the systems of internal organs and tissues. The study of the chemical composition of human exhalation can provide clinically useful information about the state of human health, while the studies are non-invasive and safe for the patient. The instrumental methods used in the study of human volatilome make it possible to online examine large numbers of patients. All this contributes to a high interest on the part of the medical community in the study of human exhaled air volatilome and suggests that the methods of these research methods have a high potential for implementation in clinical practice.
Use of autoprobiotics in the complex therapy of axial spondyloarthritis
Authors: Artemev I. A. , Ermolenko E. I. , Kotyleva M. P. , Gladysheva N. P. , Tsapieva A. N. , Gaydukova I. Z. , Chudinov A. L. , Suvorov A. N. , Maslyansky A. L.
Published: March 2023

Spondyloarthritis (SpA) is a group of chronic inflammatory diseases of the musculoskeletal system involving of the axial skeleton and extra-articular manifestations such as inflammatory bowel diseases. Some violations of the intestinal microbiome often occur during the course of spondyloarthritis. Also, intestinal dysbiosis can be enhanced by ongoing therapy. The aim of the study was to evaluate the effectiveness of combined therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) and autoprobiotics supplementation.

SpA patients treated with NSAID were divided into two groups: group A which took autoprobiotic based on indigenous culture of Enterococcus faecium, and group S which took only Supra medium, which is the basis used for making of autoprobiotic. Reducing of pain intensity, dyspeptic phenomena were observed to a greater extent in group A compared to group S. PCRRT testing revealed no significant changes in intestinal microbiocenosis in patients with SpA, except of a decrease in the Lactobacillus population, which was restored only in group A. A feature of the changes in group S was a decrease in the total bacterial mass, amounts of Bacteroides, Faecalibacterium, Enterobacter and expansion of Methanobrevibacter population. The tendency to restore the quantitative content of Lactobacillus, correlating with a decrease of IL-10 concentration, was found only in group A.

In our study the effectiveness of enterococcal auprobiotic supplementation as an element of complex therapy of patient suffering from SpA has been proven. The use of an autoprobiotic leads to a decrease in the severity of the symptoms of the disease, the leveling of dyspeptic symptoms and microbiota disorders.
Agustín Moreno, “Los estereotipos étnicos en Ab urbe condita: un estado de la cuestión”, Nova Tellus, Vol. 40, núm. 1 (2022), pp. 109-135. DOI: https://doi.org/10.19130/iifl.nt.2022.40.1.432575
Authors:   Universidad Nacional Autónoma de México - Instituto de Investigaciones Filológicas, Mexico, Cervantes Soria Aarón
Published: March 2023

Este artículo de Moreno es un documento muy útil en cuanto que nos brinda un panorama del estado que guardan los estudios sobre la problematización de la noción de "estereotipo étnico" en Ab urbe condita de Tito Livio y la metodología en la que se basó el autor para mostrarlo. Asimismo, no sólo nos da una lista de autores recientes que en sus obras han tratado el tema o han tematizado el concepto del otro y cómo representarlo, sino que también es crítico de la manera en que se ha ido desarrollando y, además de esto, señala áreas de estudio que a su parecer han sido dejadas de lado o poco consideradas y bien podrían explorarse más para mantener vivo el debate sobre cómo se narra, cómo se entiende, cómo se forja y se estereotipa a los pueblos que en apariencia están "en los márgenes" de las culturas hegemónicas, en este caso la de Roma.
Institutionalisation of social risks of digitalisation of the educational space of universities in the provincial cities of Russia
Authors: Babintsev Valentin , Serkina Yana
Published: March 2023

The article analyses the problem of institutionalisation of social risks of digitalisation of the educational space of universities in the Russian provinces. The risk- generating nature of digitalisation is emphasised, the conclusion about risk as digitalisation systemic element, that includes not only threats, but also significant opportunities for development, is substantiated. The task of managing risk genesis is formulated, the neces sary condition of which is the institutionalisation of risks. The institutionalisation of social risks of digitalisation of the educational space of universities in the provincial cit ies of Russia is interpreted as a system of actions of actors in the educational space taken to prevent undesirable consequences of the risks of digitisation and digitalisation and to use their creative potential, including the establishment of corporate norms and behavioural standards, the definition of structures that ensure their implementation in risk situations. Three main tasks of institutionalisation are considered: definition of norms and rules of risk management; formation of institutions implementing it; development and implementation of corporate standards of behaviour in risk situations.
Indemnitet i jego granice
Authors: Kropiwnicki Robert
Published: March 2023

Artykuł ma na celu zwrócenie uwagi na zagadnienie indemnitetu poprzez przedstawienie współczesnego rozumienia pojęcia immunitetu parlamentarnego, określenie granic jego działania i wskazanie jego cech (trwałość, bezwzględność, absolutność i częstotliwość). Autor skupia uwagę przede wszystkim na analizie regulacji dotyczących przedmiotowego problemu oraz poszerza ją o przywołanie licznych poglądów doktryny.
Personal library as a historical source. On the problem of studying, analyzing, and cultural value of pre-revolutionary book collections
Authors: Zhitin Ruslan M. , Topilsky Aleksey G.
Published: March 2023

The features of noble estate libraries as a historical source about the era of their existence, from the 18th to the beginning of the 20th century, are considered. The issues of mutual influence of a personal library and a bibliophile, changes in the structure of readers’ interests during the study period are analyzed. The value and functional significance of the book heritage of noble estate library collections is determined. The influence of gift inscriptions and inscriptions on the specifics of relationships in the noble environment is characterized. This approach makes it possible to reconstruct the lifestyle and culture of the bibliophile’s everyday life, to understand the motives for acquiring new publications, to compare them with the peculiarities of the time and the specifics of the local cultural environment. It is noted that even in special second-hand literature devoted to certain issues of the history of personal libraries, the authors limited themselves to stating the existence of a book collection and cited only individual facts from the history of their contents without a detailed study of the history of the appearance of a particular book, the qualitative characteristics of the repertoire of significance for the owner. The most important issues in the history of the formation and development of information culture are highlighted, the role of literature in society is determined, conclusions are drawn about the specifics of the transfer and reception of book information.
Save the revolution. Transition to a New Economic Policy as a crisis of Russian revolutionism. 1920–1921
Authors: Nikulin Viktor V.
Published: March 2023

The phenomena and events of Russian history from 1918 to the beginning of 1921, during which the Bolsheviks tried to implement the concept of a direct transition to a socialist mode of production, are analyzed. It is emphasized that the entire logic of the actions of the Bolsheviks in the economic and political spheres during this period was dictated precisely by the consistent implementation of the left-radical version of the development of the revolution, which interpreted the transition to socialism as the fastest and most complete materialization of the main provisions of the Marxist theory of socialism. It is Approved that this logic was violated at the beginning of 1921, when, under the influence of a total economic and political crisis, there was a direct threat to the gains of the revolution and the loss of socialist identity, it was decided to switch to the New Economic Policy. The transition to the New Economic Policy is interpreted as an obvious crisis of Russian revolutionism in the Bolshevik variation, expressed in the collapse of hopes for a quick and direct transition from capitalism to socialism.
Chatbots in teaching a foreign language: advantages and controversial issues
Authors: Sysoyev Pavel V. , Filatov Evgeny M.
Published: March 2023

The current stage of technological development of the world community is characterized by the dynamic introduction of artificial intelligence technologies into various spheres of human life. Informatization of education contributed to the integration of new innovative technologies in the teaching of certain subjects, including a foreign language. Chatbots are one of the modern programs that operate on the basis of natural language processing and machine learning technologies, which can be used in the development of students’ foreign language speech skills. By chatbots from the standpoint of the methodology of teaching foreign languages, we propose to understand a dialog training program capable of developing foreign-language oral and written speech skills of a student based on the algorithms of human speech behavior embedded in it by maintaining a dialogue with him and imitating human speech. In this work, based on the analysis of methodological research, we highlight the advantages of chatbots in teaching a foreign language and the controversial issues of using this program in the educational process. The advantages include the following: 1) increasing students' motivation to learn a foreign language based on innovative artificial intelligence technology; 2) the opportunity for students to improve foreign language speech skills; 3) the availability of chatbots for the development of students' speech skills, regardless of their location and time; 4) reducing the level of anxiety of students when interacting with the machine. The controversial issues include: 1) students are not always ready to replace the teacher with a chatbot; 2) most of the conversational chatbots are aimed at students with a level of foreign language proficiency A2-B1; 3) stereotyped and limited set of phrases used by the chatbot.
Feature Selection in the Context of Prognostic Health Management
Authors: Wardhana Indrawata
Published: March 2023

In the chemical processing industries, sensors for pumps are among the most commonly used machinery. Condition-based maintenance (CBM) and prognosis health management (PHM) determine the most cost-effective time to overhaul pumps. In order to determine the status of the pump, a signal-emitting accelerometer is employed. Stationarity-based feature extraction from amplitude signals is used to process the signal. Utilizing the time-domain function, multiple statistical results were produced. Eight fault codes were classified using support vector machine method. The enormous amount of data points necessitated the use of feature selection. In terms of accuracy, precision, recall, and F1 score, the Chi-square feature selection method exceeds other approaches.
Thermal Conductivity of Carbides and Nitrides of Zr, Th and U: Numerical Approach
Authors: Kizka Valeriy
Published: March 2023

Using number theory, a formula is obtained that describes the thermal conductivities of ZrC, UC, UN, ThN, ZrN and ThxU1-xN at x = 0.2 and 0.5 with temperature change. This formula contains the atomic numbers of the elements, the thermal conductivities of the individual elements of the substance, and the structural parameter. There is no direct dependence on temperature in the formula, since it is hidden in the thermal conductivities of each element and in the structure parameter. In some temperature ranges, the structural parameter is constant; therefore, the thermal conductivity of some carbides and nitrides is expressed through summing the thermal conductivities of individual elements.
Türkiye’deki Cari Açık Sorunu: Yapısal Nedenleri ve Çözüm Önerileri
Authors: IRMAK Esma
Published: March 2023

Cari işlemler dengesinin, ekonominin en önemli hesap grubu olduğu konusunda genel kabul vardır. Cari işlemler açığı, özelikle gelişmekte olan ülkeler için istikrarlı bir ekonomik yapıya ulaşma hedefine engel olmaktadır. Bir ülkenin cari işlemler hesabı açık verdiğinde; dışarıdan gelen paradan daha fazlasını göndermiş demektir. Ayrıca yaşanan ekonomik krizlerin en önemli tetikleyicilerinden biri olması, konunun güncelliğini ve önemini korumaktadır. 1980’den sonra Türkiye ekonomisinin en önemli sıkıntısı olarak yıllar itibariyle sürekli hale gelmiştir. Türkiye’de özelikle 2001 krizi ile artan cari açık, 2011 sonrasında azalma eğilimine girmişse de ciddi oranda kalıcı hale gelmiştir. Türkiye’nin cari açık sorunu konusunda ortak görüşler bulunmaktadır. Enerji ihtiyacında dışarıya olan aşırı bağımlılık, yatırım-tasarruf oranı, dış ticaret dengesi ve cari açığın finansman yapısı en önemli faktörler olarak belirtilmektedir. Bu çalışmanın amacı, Türkiye’nin 2000-2021 yılları arasında sahip olduğu cari işlemler dengesini incelemektir. Bu hesap grubuna ait belirleyiciler ile açıkların nasıl finanse edildiği ve açıklara neden olan yapısal nedenlere karşı çözüm önerileri sunmaktır.
ARTDECO
Authors:   , Castellares Cerna Katharine Andrea , Florida Huayhuas Dante Brandy , Mendoza Collantes Airam Pierina , Zuñiga Paguada Erick Peter
Published: March 2023

El presente plan de negocio, examina, observa e identifica la viabilidad del proyecto empresarial “Art Deco S.A.C”. Empresa enfocada a realizar y comercializar relojes personalizados elaborados a base de discos de vinilo. El proyecto surge debido a que los discos de vinilo en la actualidad son obsoletos, puesto que nos encontramos en la era tecnológica, nosotros observamos una oportunidad de generar a estos discos un valor adicional, el cual es presentarlo como base para la formación de un reloj de pared, el cual adicionalmente va a tener diseños personalizados al gusto y preferencia de cada cliente. Los factores que Art Deco, perciben como claves para el éxito son que actualmente en el mercado no se presenta mucha competencia directa con este tipo de productos, lo cual se presenta como una gran oportunidad para poder ingresar, mantenerse y ser líderes en este rubro.
Clima organizacional y satisfacción laboral en la empresa Praxis Ecology SAC, Ate Vitarte, Lima - 2020
Authors:   , Ortiz Valero Johana Delsi , Ortiz Silvera Edwin Ramiro , Chahuaylacc Soto Johan Bryan , Chumbimune Cajahuaringa Andrés
Published: March 2023

En los últimos años se ha venido dando una gran importancia al lugar que ocupan los colaboradores en las organizaciones. El foco de atención ha recaído, entre otros temas, en el clima laboral de las organizaciones. En esta investigación se estableció como objetivo principal, el describir la relación en el clima organizacional y la satisfacción laboral en la empresa Praxis Ecology SAC, Ate Vitarte, Lima – 2020. Para alcanzar dicho objetivo se planteó la investigación desde un enfoque cuantitativo, con un diseño no experimental, transversal. Se tomó como población 50 trabajadores de la empresa objeto de estudio. Una vez realizado el estudio se dedujo que la relación entre clima organización y la satisfacción laboral, es una relación significativa. Éste último mejora si también lo hace el clima organizacional. En esta mejora juega un papel importante la comunicación, tanto vertical como horizontal, el modelo de liderazgo y la motivación a los colaboradores.
Empatía y felicidad en estudiantes de la carrera de Psicología de una Universidad Privada de Lima Metropolitana en tiempos de la COVID-19
Authors:   , Marmolejo Loza Omar Lizandro , Rea Añanca Rosaluz Steffany , Ucedo Quispe Roxana
Published: March 2023

El objetivo de la presente investigación es determinar la relación entre empatía y felicidad en los estudiantes de la carrera de Psicología de una Universidad Privada de Lima Metropolitana en tiempos de la COVID-19. La muestra está compuesta por 98 estudiantes universitarios; quienes se encuentran dentro del rango de edad de entre 18 y 27 años aproximadamente. La investigación es de enfoque cuantitativo, tipo descriptivo correlacional, diseño no experimental y corte transversal. Se hizo uso de los instrumentos Test de empatía cognitiva y afectiva (TECA) y la Escala de la felicidad de Lima. Los resultados obtenidos determinaron que no existe relación entre las variables de empatía y felicidad, sin embargo, se encontró relación entre el factor 4: alegría de vivir y la variable empatía.
Presencia de Escherichia coli multidrogo-resistente en urocultivos asociado al ambiente ambulatorio y hospitalario del Instituto Nacional Materno Perinatal de Lima en el 2018
Authors:   , Blas Fernández Wendy Victoria , Gerónimo Flores Ida Brenda
Published: March 2023

Introducción: En los últimos años, se ha incrementado el nivel de resistencia antibiótica en cepas de Escherichia coli asociadas a infecciones urinarias dificultando el tratamiento empírico. Objetivo: Determinar la frecuencia de E. coli Multidrogo Resistente (MDR) y productoras de Beta-lactamasas de espectro extendido (βLEE) aislado en urocultivos en ambientes ambulatorios y áreas hospitalarias en mujeres en edad fértil del Instituto Nacional Materno Perinatal (INMP) de Lima - Perú en el 2018. Materiales y métodos: El presente estudio es de tipo observacional analítico de corte transversal. Durante el periodo de 6 meses, se analizaron un total de 291 pacientes con urocultivos positivos para E.coli, el 18.21% (53/291) de áreas hospitalarias y el 81.79% (238/291) de ambulatorios. Los niveles de sensibilidad se evaluaron mediante disco-difusión en agar e interpretados con la guía CLSI. Resultados. Un 53.61% fueron MDR y 28.9% productoras de βLEE, ambos más frecuentes en el ambiente hospitalario con 69.8% MDR (p<0.01) y 47.2% βLEE (p<0.001). Se encontró alta resistencia a las quinolonas, como ciprofloxacino 90.5%. La resistencia a cefalosporinas y aztreonam, fue significativamente más alta en ambientes hospitalarios (p<0.05). Se identificaron una gran diversidad de perfiles de resistencia en ambos ambientes. Conclusiones. La presencia de cepas MDR y βLEE se asoció con encontrarse en ambientes hospitalarios, lo cual debería ser considerado para iniciar un tratamiento empírico. A la vez se debe implementar un mejor control sobre el uso de antimicrobianos.