bluuebunny/crossref_metadata_2025 huggingface dataset:
Remote olfactory assessment using the NIH Toolbox Odor Identification test and the brain health registry
Authors: Jaén Cristina , Maute Christopher , Mackin Scott , Camacho Monica R. , Truran Diana , Nosheny Rachel , Weiner Michael W. , Dalton Pamela
Published: April 2024

Background

Early identification of deficits in our ability to perceive odors is important as many normal (i.e., aging) and pathological (i.e., sinusitis, viral, neurodegeneration) processes can result in diminished olfactory function. To realistically enable population-level measurements of olfaction, validated olfaction tests must be capable of being administered outside the research laboratory and clinical setting.

Aim

The purpose of this study was to determine the feasibility of remotely testing olfactory performance using a test that was developed with funding from the National Institutes of Health as part of a ready-to-use, non-proprietary set of measurements useful for epidemiologic studies (NIH Toolbox Odor ID Test).

Materials and methods

Eligible participants older than 39 years and active (within 6 months) in the Brain Health Registry (BHR), an online cognitive assessment platform which connects participants with researchers, were recruited for this study. Interested participants were mailed the NIH Toolbox Odor ID Test along with instructions on accessing a website to record their responses. Data obtained from subjects who performed the test at home was compared to the normative data collected when the NIH Toolbox Odor ID Test was administered by a tester in a research setting and validated against the Smell Identification Test. The age-range and composition of the population ensured we had the ability to observe both age-related decline and gender-related deficits in olfactory ability, as shown in the experimental setting.

Results

We observed that age-associated olfactory decline and gender-associated performance was comparable to performance on the administered test. Self-administration of this test showed the age-related loss in olfactory acuity, F(4, 1156)=14.564, p<.0001 as well as higher accuracy for women compared to men after controlling for participants’ age, F(1, 1160) = 22.953, p <.0001. The effect size calculated as Hedge’s g, was 0.41.

Conclusion

These results indicate that the NIH Toolbox Odor ID Test is an appropriate instrument for self-administered assessment of olfactory performance. The ability to self-administer an inexpensive olfactory test increases its utility for inclusion in longitudinal epidemiological studies and when in-person testing is not feasible.
Comparative stability analysis of Indonesian banks: Markov Switching—Dynamic Regression for Islamic and conventional sectors
Authors: Mawardi Imron , Al Mustofa Muhammad Ubaidillah , Widiastuti Tika , Fanani Sunan , Bakri Mohammed Hariri , Hanafi Zainal , Robani Anidah
Published: April 2024

The banking industry necessitates implementing an early warning system to effectively identify the factors that impact bank managers and enable them to make informed decisions, thereby mitigating systemic risk. Identifying factors that influence banks in times of stability and crisis is crucial, as it ultimately contributes to developing an improved early warning system. This study undertakes a comparative analysis of the stability of Indonesian Islamic and conventional banking across distinct economic regimes—crisis and stability. We analyze monthly banking data from December 2007 to November 2022 using the Markov Switching Dynamic Regression technique. The study focuses on conducting a comparative analysis between Islamic banks, represented by Islamic Commercial Bank (ICB) and Islamic Rural Bank (IRB), and conventional banks, represented by the Conventional Commercial Bank (CCB) and Conventional Rural Bank (CRB). The findings reveal that both Islamic and conventional banks exhibit a higher probability of being in a stable regime than a crisis regime. Notably, Islamic banks demonstrate a greater propensity to remain in a stable regime than their conventional counterparts. However, in a crisis regime, the likelihood of recovery for Sharia-compliant institutions is lower than for conventional banks. Furthermore, our analysis indicates that larger banks exhibit higher stability than their smaller counterparts regarding assets and size. This study pioneers a comprehensive comparison of the Z-score, employed as a proxy for stability, between two distinct classifications of Indonesian banks: Sharia (ICB and IRB) and conventional (CCB and CRB). The result is expected to improve our awareness of the elements that affect the stability of Islamic and conventional banking in Indonesia, leading to a deeper comprehension of their dynamics.
Development of a long term, ex vivo, patient-derived explant model of endometrial cancer
Authors: van der Woude Hannah , Phan Khoi , Kenwright Diane N. , Goossens Louise , Hally Kathryn Elizabeth , Currie Margaret Jane , Kokkinos John , Sharbeen George , Phillips Phoebe A. , Henry Claire Elizabeth
Published: April 2024

Incidence of endometrial cancer (EC) is rising in the developed world. The current standard of care, hysterectomy, is often infeasible for younger patients and those with high body mass index. There are limited non-surgical treatment options and a lack of biologically relevant research models to investigate novel alternatives to surgery for EC. The aim of the present study was to develop a long-term, patient-derived explant (PDE) model of early-stage EC and demonstrate its use for investigating predictive biomarkers for a current non-surgical treatment option, the levonorgestrel intra-uterine system (LNG-IUS). Fresh tumour specimens were obtained from patients with early-stage endometrioid EC. Tumours were cut into explants, cultured on media-soaked gelatin sponges for up to 21 days and treated with LNG. Formalin-fixed, paraffin embedded (FFPE) blocks were generated for each explant after 21 days in culture. Tumour architecture and integrity were assessed by haematoxylin and eosin (H&E) and immunohistochemistry (IHC). IHC was additionally performed for the expression of five candidate biomarkers of LNG resistance. The developed ex vivo PDE model is capable of culturing explants from early-stage EC tumours long-term (21 Days). This model can complement existing models and may serve as a tool to validate results obtained in higher-throughput in vitro studies. Our study provides the foundation to validate the extent to which EC PDEs reflect patient response in future research.
How attitudes of state and community leaders regarding health equity and social determinants of health are associated with behavioral intentions to improve population health
Authors: Williams Nyna , Newton-Hoe Emily , Kovac Martha
Published: April 2024

A critical driver of population health, well-being, and equity is making health a shared value, or the belief that health is a priority for oneself and one’s community. For people in positions of influence, attitudes regarding their organization’s perspective may result in decisions that advance health equity or reinforce inequities. Yet despite the potential role of leaders in influencing health and well-being, little is known about their attitudes regarding their organization’s perspective on what shapes health, or how their attitudes translate into actions that improve population health. The objectives of this study are twofold: (1) to understand leaders’ attitudes with regard to their organization’s perspective on population health and (2) to identify the attitudes associated with leaders’ perspectives regarding their organization’s intention to engage in behaviors that advance population health. We designed a survey instrument grounded in the Theory of Planned Behavior and fielded the survey to 18,367 state and community leaders across all 50 U.S. states, 325 U.S. cities, and nine sectors from fall 2020 until spring 2022. We received surveys from 5,450 leaders, yielding a 32 percent response rate. Survey respondents viewed social determinants of health and health equity as important factors influencing population health. Additionally, two attitudes were most associated with leaders’ intentions to promote population health—“self-efficacy” (a leader’s confidence in taking action to promote health for all) and “behaviors valued by important others” (how much certain groups want the organization to take action that promotes health for all). Efforts to improve population health through leaders should focus on supporting leaders’ self-efficacy and on increasing leaders’ perceptions regarding behaviors valued by important others. Governmental entities and funders can use these data to support leaders’ efforts in improving population health, well-being, and equity.
Temporal analysis of genetic diversity and gene flow in the threatened catfish Pseudoplatystoma magdaleniatum from a dammed neotropical river
Authors: García-Castro Kevin León , Márquez Edna Judith
Published: April 2024

The striped catfish Pseudoplatystoma magdaleniatum is a large-sized migratory species from the north Andes region, endemic to Magdalena basin and one of the major fishery resources. Despite the estimated reduction of over 80% of the fisheries production of this species throughout the basin in recent decades, its population in the lower Magdalena-Cauca basin showed healthy genetics after molecular analyses. However, the current conservation status of this species and several habitat disturbances demand the re-evaluation of its population genetics to infer evolutionary risks and assess potential changes. This work analyzed a total of 164 samples from the Cauca River collected downstream the Ituango Dam between 2019–2021 using species-specific microsatellite markers to compare the genetic diversity and structure in samples collected between 2010–2014 from the lower Magdalena-Cauca basin, previously analyzed. Our results showed a relatively stable panmictic population over time (4 to 10 years), with high genetic diversity and evidence of recent bottleneck. Promoting habitat connectivity to conserve gene flow, characterizing diversity and genetic structure over the entire basin, and integrating the results with future monitoring are important aspects for the management planning for P. magdaleniatum in the Magdalena-Cauca basin.
Enteroaggregative Escherichia coli in mid-Norway: A prospective, case control study
Authors: Haugan Ingvild , Husby Marit Gudrun , Skjøtskift Bjørg , Aamnes Mostue Dorothea , Brun Andreas , Olsen Lene Christin , Simpson Melanie Rae , Lange Heidi , Afset Jan Egil
Published: April 2024

Background

The use of molecular methods has led to increased detection of Enteroaggregative Escherichia coli (EAEC) in faecal samples. Studies have yielded conflicting results regarding the clinical relevance of this finding. The objective of this study was to investigate the prevalence of EAEC in faecal samples from patients with diarrhoea and healthy controls and describe characteristics of EAEC positive persons.

Methods

From March 1st, 2017 to February 28th, 2019, we investigated all consecutive faecal samples from patients with diarrhoea received at the laboratory and collected faecal samples from randomly invited healthy controls from mid-Norway. Real-time multiplex PCR was used for detection of bacterial, viral, and parasitic pathogens. We registered sex, age, urban versus non-urban residency, and travel history for all participants. Statistical analyses were performed with Pearson chi-squared test, Kruskal-Wallis test, and Mann-Whitney U test.

Results

We identified EAEC in 440 of 9487 (4.6%) patients with diarrhoea and 8 of 375 (2.2%) healthy controls. The EAEC prevalence was 19.1% among those with diarrhoea and recent foreign travel and 2.2% in those without travel history independent of diarrhoea. Concomitant pathogens were detected in 64.3% of EAEC-positive patients with diarrhoea. The median age was 28.5 in those with EAEC-positive diarrhoea and 38 in those with EAEC-negative diarrhoea (p <0.01). In patients with diarrhoea, travel was reported in 72% of those with EAEC and concomitant pathogens, and 54% and 12% in those with only EAEC and no EAEC, respectively (p <0.01).

Conclusions

EAEC was a common detection, particularly in patients with diarrhoea and recent international travel, and was found together with other intestinal pathogens in the majority of cases. Our results suggest that domestically acquired EAEC is not associated with diarrhoea. Patients with EAEC-positive diarrhoea and concomitant pathogens were young and often reported recent travel history compared to other patients with diarrhoea.
Development and validation of the Multidimensional Gender Inequality Perception Scale (MuGIPS)
Authors: Schwartz-Salazar Sofía , García-Sánchez Efraín , Martínez Rocío , Rodríguez-Bailón Rosa
Published: April 2024

Perceptions of gender inequality may motivate people to take action against inequality given its negative impact on various domains of people’s everyday lives. Thus, it is crucial to develop reliable measures that consider the multidimensional nature of gender inequalities. In this research, we propose and assess the psychometric properties of the Multidimensional Gender Inequality Perception Scale (MuGIPS). This is a self-reported measure of perceived gender inequality in four domains: health, violence, household work and caregiving, and public sphere and power. Exploratory and confirmatory factor analyses were conducted to test the validity and reliability of the MuGIPS with Spanish participants in three samples (N = 1733). The analyses revealed that the MuGIPS had a good internal consistency and showed four factors associated with gender inequality in the four specified domains. Moreover, scores in all the dimensions positively correlated with feminist identity and feminist ideology, as much as with some attitudinal variables. In contrast, results showed a negative correlation with system-justifying ideologies. The MuGIPS shows adequate reliability and validity for measuring the perception of gender inequality in the health, violence, household work and caregiving, and public sphere and power domains among Spanish university and general population samples.
The relationship between family socioeconomic status and the young children’s number sense development: The mediating role of parent-child activities
Authors: Jiang Ying , Wang Xiaofen
Published: April 2024

This study examines the relationship between family socioeconomic status, parent-child activities, and young children’s digital development. Using the Family SES questionnaire, the parent-child activities questionnaire, and the 5 to 6 year old children’s number sense development scale as research instruments, 314 young children (M = 70.42, SD = 3.47). The results show that: (1) Family Socioeconomic Status can significantly positively predict the young children’s number sense development; (2) Parent-child activities play a partial mediating role in the relationship between family socioeconomic status and the young children’s number sense development. This study provides specific guidelines and recommendations for improving the young children’s number sense development.
Relationship between health literacy and health-related quality of life in Korean adults with chronic diseases
Authors: Song Inmyung
Published: April 2024

Inadequate health literacy is a risk factor for poor health outcomes and health-related quality of life (HRQoL). So far, the impact of health literacy on HRQoL has been examined for only a few chronic conditions. In this contribution, the relationship between health literacy and HRQoL in Korean adults with chronic conditions is examined using data of the cross-sectional Korea Health Panel Survey from 2021. Health literacy was measured with the 16-item European Health Literacy Survey Questionnaire (HLS-EU-Q16) and HRQoL with the European Quality of Life-5 Dimensions (EQ-5D). Multiple linear regression model was run for the EQ-5D index as the dependent variable. Multiple logistic regression models were implemented for responses to the individual EQ-5D items. 30.8%, 24.6%, and 44.6% of participants had inadequate, marginal, and adequate levels of health literacy, respectively. The EQ-5D index increases with marginal (B = 0.018, p<0.001) and adequate literacy (B = 0.017, p<0.001) compared to inadequate literacy. People with adequate or marginal literacy were more likely to report no problem with mobility (odds ration [OR] = 1.5; p<0.001), self-care (OR = 1.6; p<0.05), and usual activities (OR = 1.6 for adequate; OR = 1.4 for marginal; p<0.01) than those with inadequate literacy. Adequate health literacy was associated with an increased likelihood of having no problem with anxiety and depression (OR = 1.4; p<0.05). In conclusion, inadequate health literacy is prevalent among Korean adults with chronic diseases. Adequate health literacy is associated with better HRQoL and a protective factor for four dimensions of EQ-5D (mobility, self-care, usual activities, and anxiety/depression).
Resilience analysis and improvement strategy of microgrid system considering new energy connection
Authors: Zhou Yongrong , Zhao Yan , Ma Zhaoxing
Published: April 2024

With the increasing demand for electricity, microgrid systems are facing issues such as insufficient backup capacity, frequent load switching, and frequent malfunctions, making research on microgrid resilience crucial, especially to improve system power supply reliability. This paper proposes a method for analyzing the resilience metric of new energy grid-connected microgrid system, and proposes optimization strategies to improve resilience. Firstly, a measurement method for the resilience of the microgrid system is established based on the operating characteristics of the system components. Secondly, the sensitivity relationship between system resilience and parameters is established, and an optimization model for resilience improvement strategies of microgrid systems based on parameter sensitivity is constructed. Finally, simulation verification is conducted based on the IEEE 37-node microgrid system. The results show that the proposed measurement method can scientifically and reasonably measure the resilience of the microgrid system, and the resilience improvement strategy significantly improves the operational resilience, verifying the effectiveness and robustness of the proposed analysis method.
An integrated model for rice supplier selection strategies and a comparative analysis of fuzzy multicriteria decision-making approaches based on the fuzzy entropy weight method for evaluating rice suppliers
Authors: Magableh Ghazi M.
Published: April 2024

Rice, being a staple food in many countries, necessitates the identification of reliable suppliers to ensure a steady supply. Consequently, it is vital to establish trustworthy vendors for various types of this essential grain who can meet stringent product quality standards. This study aims to identify, analyze, rank, and select primary rice suppliers. The study emphasizes the importance of selecting and managing suitable providers to meet customer demands, proposes a ranking model for rice suppliers, and introduces developed fuzzy MCDM techniques. It proposes an integrated model for selecting rice suppliers, considering factors related to the processes before, during, and after selecting providers within a defined framework. The outcomes shows that rice supplier selection strategy can efficiently identify reliable rice suppliers, improve buyer value, reduce procurement risk, enhance efficiency, and establish strong supply chain relationships in complex decision-making processes. To assess suppliers, the study introduces two advanced integrated approaches and compares them. The fuzzy entropy weight method (EWM) was used to determine the criteria weights. The ranking of rice suppliers was achieved using a fuzzy multi-objective optimization based on ratio analysis (MOORA), fuzzy complex proportional assessment (COPRAS), and combinations of these two methods in different approaches. The methodology supports decision-makers in a rapidly evolving global environment by assisting importers, traders, suppliers, procurement, and logistics management, particularly for non-rice-cultivating countries in rice importation and supplier selection. The numerical analysis is grounded in a real-world case study of selecting rice suppliers in Jordan. The findings reveal that the various strategies yield both similar and different results. Furthermore, the integrated method is considered the most accurate for evaluating rice imports and suppliers, aligning closely with the reality of the current situation.
Effect of maternal age on ATP content and distribution of mitochondria in bovine oocytes
Authors: Dadarwal Dinesh , Pfeifer Luiz , Cervantes Miriam , Adams Gregg P. , Singh Jaswant
Published: April 2024

Our objective was to understand how maternal age influences the mitochondrial population and ATP content of in vivo matured bovine oocytes. We hypothesized that in vivo matured oocytes from older cows would have altered mitochondrial number and distribution patterns and lower cytoplasmic ATP content compared to the oocytes obtained from younger cows. Follicles ≥5mm were ablated in old cows (13 to 22 yrs, Old Group, n = 7) and their younger daughters (4 to 10 years old, Young Group; n = 7) to induce the emergence of a new follicular wave. Cows were treated twice daily with eight doses of FSH starting 24 hr after ablation (Day 0, day of wave emergence). Prostaglandin F2alpha (PGF) was given on Days 3 and 3.5, LH on Day 4.5, and cumulus-oocyte-complexes were collected 18–20 hours post-LH by ultrasound-guided follicular aspiration. Oocytes were either processed for staining with MitoTracker Deep Red FM or for ATP assay. Stained oocytes were imaged with a Zeiss LSM 710 confocal microscope, and mitochondria were segmented in the oocyte volume sets using Imaris Pro 7.4. In vivo matured oocytes obtained from old cows were similar in morphological grades to those from young cows. However, the oocytes of COC from older cows had 23% less intracellular ATP (27.4±1.9 vs 35.7±2.2 pmol per oocyte, P = 0.01) than those of young cows. Furthermore, the average volume of individual mitochondria, indicated by the number of image voxels, was greater (P<0.05) in oocytes from older cows than in those from younger cows. Oocytes from older cows also tended to have a greater number of mitochondrial clusters (P = 0.06) and an increased number of clusters in the central region of the oocytes (P = 0.04) compared to those from younger cows. In conclusion, our study demonstrated that maternal age was associated with a decrease in the cytoplasmic ATP content of in vivo mature oocytes and an altered distribution of mitochondrial structures. These findings suggest that maternal age may negatively influence the developmental competence of oocytes from older cows.
Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody
Authors: Phan Tin , Zitzmann Carolin , Chew Kara W. , Smith Davey M. , Daar Eric S. , Wohl David A. , Eron Joseph J. , Currier Judith S. , Hughes Michael D. , Choudhary Manish C. , Deo Rinki , Li Jonathan Z. , Ribeiro Ruy M. , Ke Ruian , Perelson Alan S. ,   for the ACTIV-2/A5401 Study Team
Published: April 2024

To mitigate the loss of lives during the COVID-19 pandemic, emergency use authorization was given to several anti-SARS-CoV-2 monoclonal antibody (mAb) therapies for the treatment of mild-to-moderate COVID-19 in patients with a high risk of progressing to severe disease. Monoclonal antibodies used to treat SARS-CoV-2 target the spike protein of the virus and block its ability to enter and infect target cells. Monoclonal antibody therapy can thus accelerate the decline in viral load and lower hospitalization rates among high-risk patients with variants susceptible to mAb therapy. However, viral resistance has been observed, in some cases leading to a transient viral rebound that can be as large as 3–4 orders of magnitude. As mAbs represent a proven treatment choice for SARS-CoV-2 and other viral infections, evaluation of treatment-emergent mAb resistance can help uncover underlying pathobiology of SARS-CoV-2 infection and may also help in the development of the next generation of mAb therapies. Although resistance can be expected, the large rebounds observed are much more difficult to explain. We hypothesize replenishment of target cells is necessary to generate the high transient viral rebound. Thus, we formulated two models with different mechanisms for target cell replenishment (homeostatic proliferation and return from an innate immune response antiviral state) and fit them to data from persons with SARS-CoV-2 treated with a mAb. We showed that both models can explain the emergence of resistant virus associated with high transient viral rebounds. We found that variations in the target cell supply rate and adaptive immunity parameters have a strong impact on the magnitude or observability of the viral rebound associated with the emergence of resistant virus. Both variations in target cell supply rate and adaptive immunity parameters may explain why only some individuals develop observable transient resistant viral rebound. Our study highlights the conditions that can lead to resistance and subsequent viral rebound in mAb treatments during acute infection.
Disfigment Bankrupsea
Authors: Bale Robin
Published: April 2024

This article treats the temporality of writing as a place or event – which is to say somewhere which must be arrived at on time or otherwise. This arrival is vulnerable to the vicissitudes that all physical bodies/places can undergo: alteration in one’s absence, disappearance or loss. This contribution re-presents a piece of work that I produced about a place and then mislaid before it could be presented in the form that I hoped it would take. The place that it was a response to has also been lost. Both the writer of the place/event and their reader thus experience a form of belatedness. What made the place live in my mind so intensely was a series of texts scrawled on its wall, interspersed with images. I was late arriving for that. I address the reader as a latecomer in turn.
Impact of Body Composition on Esophagogastric Junction Opening Measures: Discordant FLIP and Manometric Findings Are More Common With Increased Body Mass Index
Authors: Flanagan Ryan , Muftah Mayssan , Hiramoto Brent , Cai Jennifer X. , Chan Walter W.
Published: April 2024

INTRODUCTION:

Increased intra-abdominal pressure in patients with elevated body mass index (BMI) may affect measurements of esophagogastric junction (EGJ) opening.

METHODS:

Findings from adult patients who underwent both impedance planimetry with functional luminal imaging probe (FLIP) and high-resolution manometry (HRM) were compared by BMI.

RESULTS:

Among patients with no EGJ outflow obstruction on HRM, abnormal EGJ classifications on FLIP were more common among those with elevated than normal BMI (61.1% vs 31.6%, P = 0.037).

DISCUSSION:

Discordant results between FLIP and HRM on EGJ opening are more common in patients with elevated BMI. Body composition may impact EGJ function and measures on current testing modalities.
Reabilitação de dentes anteriores com restaurações de resina composta direta: três anos de acompanhamento
Authors: Gerard Lucas Neitzel , Cocco Alexandra Rubin , Lund Rafael Guerra , Baldissera Rudimar Antônio , Martos Josué
Published: April 2024

RESUMO: Introdução: fraturas em dentes anteriores são consideradas, frequentemente, como emergência na prática odontológica. A reabilitação estética e funcional é o principal objetivo do tratamento. Fraturas de coroa não consideradas complicadas envolvem esmalte e dentina e podem receber diferentes níveis de tratamento, tais como colagem do elemento dentário ou restauração com materiais compósitos. Objetivo: relatar uma abordagem terapêutica breve de três casos de pacientes que sofreram diferentes graus de fraturas de coroas não complicadas em incisivos centrais superiores permanentes que foram tratados com restaurações com resina composta direta. Resultados: o tratamento estético e funcional com restaurações de resina composta foi realizado nos três casos. Conclusão: três anos de acompanhamento com exames clínicos e radiográficos revelaram uma reabilitação bem-sucedida dos dentes fraturados.
Resistência de união entre cerâmica dissilicato de lítio processada por diferentes métodos e cimento resinoso sob diferentes tratamentos de superfície da cerâmica
Authors: Ferraz Anália Gabriella Borges , Spohr Ana Maria , Bellan Mariá Cortina , Miranzi Benito André Silveira , Borges Luis Henrique , Calabrez Filho Saturnino , Borges Gilberto Antônio
Published: April 2024

RESUMO: Objetivo: avaliar o efeito de diferentes tratamentos de superfície e o processamento de uma cerâmica à base de dissilicato de lítio sobre a resistência de união e características interfaciais com um cimento resinoso fotoativado. Material e Métodos: foram confeccionados 20 blocos prensados (IPS e.max Press) e 20 na técnica CAD/CAM (IPS e.max CAD) (10 mm de diâmetro x 1 mm de espessura). Cada tipo de processamento foi dividido em quatro grupos (n = 5), de acordo com o tipo de tratamento de superfície, totalizando oito grupos experimentais: NT = sem tratamento de superfície; HFS = 10% de ácido fluorídrico (HF) e aplicação de silano; HFU = HF 10% e adesivo universal; e EP = aplicação de primer. Após o preparo, as amostras foram armazenadas em água destilada por 24h a 37 °C e submetidas ao teste de resistência de união. Os valores de resistência de união, em MPa, foram analisados pelos testes t de Student, Kruskal-Wallis e Student-Newman-Keuls (p > 0,05), imagens em microscopia eletrônica de varredura (MEV) foram realizadas para análise qualitativa do padrão de fratura, após o teste de resistência de união, e espécimes foram fabricados para análise da interface cimento/cerâmica. Resultados e Conclusão: os tratamentos HFU (16,8 ± 3,51 MPa) e EP (12,9 ± 3,05 MPa) apresentaram os melhores valores de resistência de união para cerâmicas prensadas, sendo estatisticamente melhores do que HFU e EP de cerâmicas CAD/CAM. Entre as cerâmicas CAD/CAM, os melhores valores foram apresentados pelo tratamento HFS (8,17 ± 4,8 MPa), que é estatisticamente similar ao HFS prensado (5,92 ± 3,51 MPa). Apenas os grupos NT apresentaram falhas/gaps na interface cerâmica/cimento e padrão de fratura adesiva em MEV. Os demais grupos apresentaram um padrão de fratura mista, sem significativas falhas/gaps na interface cerâmica/cimento. Os tratamentos HFU e EP mostraram-se os melhores para as cerâmicas prensadas; e os HFS e HFU, para as cerâmicas CAD/CAM. Imagens SEM não mostraram diferenças significativas entre os tipos de tratamento de superfície, exceto NTs.
POR QUE devemos entender a OCLUSÃO?
Authors: Palmieri João
Published: April 2024

Qual seria a justificativa para uma coluna tratando da oclusão dentária em uma renomada revista de Odontologia Estética? Poderia ser dito que, devido à popularização dos tratamentos cosméticos, o surgimento de fracassos inexplicáveis apontou para a necessidade de entendermos melhor como funciona o sistema mastigatório. E mais: que a expectativa é que entendendo como funciona a oclusão, os fracassos dos tratamentos estéticos poderiam ser evitados. O uso do futuro do pretérito indica que atribuir toda a responsabilidade pelo sucesso ou fracasso de nossos tratamentos à oclusão pode não ser muito prudente.
Influência do aparelho fotoativador sobre o grau de conversão de resinas bulk-fill
Authors: Schneider Luis Felipe Jochims , Carmello Ana Carolina , Pereira Leonardo Duarte Eiras , Couto Neto Mário Pereira , Modena Rodrigo Antonio , Cavalcante Larissa Maria
Published: April 2024

RESUMO: Objetivos: a) determinar a influência do aparelho fotoativador ("monowave" e "polywave") sobre o grau de conversão (GC) em razão da profundidade, quando testadas diferentes formulações de resinas bulk-fill; b) determinar qual parâmetro de avaliação de luz é capaz de predizer a capacidade de fotoativação em razão da profundidade de compósitos bulk-fill e c) verificar se esses parâmetros estão relacionados ao custo da fonte de luz. Métodos: foram usadas quatro fontes do tipo LED (Poly Wireless/Kavo Kerr; Radii-Cal/SDI; Bluephase G2/Ivoclar Vivadent; Valo Cordless/Ultradent) e três compósitos do tipo bulk-fill (Aura BF/SDI, consistência regular e iniciador convencional; Tetric N-Ceram BF/Ivoclar Vivadent, consistência regular e iniciador alternativo; Surefill SDR/Dentsply Sirona, fluida). Para cada material, o tempo de ativação foi aquele indicado pelo fabricante e o GC (%) foi determinado por espectroscopia FTIR (n=5) na subsuperfície (0,1 mm) e a 4 mm de profundidade. Análises de correlação foram realizadas: a) entre os dados de irradiância das fontes de luz e os de conversão das resinas compostas; e b) entre os valores de irradiância nas diferentes formas de análise e o custo das fontes de luz. Os resultados foram submetidos à análise de variância e ao teste de Tukey (95%). Resultados: para Aura BF, a fonte de luz não influenciou o GC na subsuperfície, mas o uso da fonte RadiCall reduziu o GC em 4 mm. Para Tetric N-Ceram BF, os aparelhos de pico duplo (polywave) Bluephase G2 e Valo Cordless produziram valores superiores àqueles de pico único (monowave) Poly Wireless e Radii-Cal. Para a resina Surefill SDR, a conversão foi uniforme em toda a profundidade, independentemente do aparelho utilizado. Houve correlação positiva entre os valores de irradiância e a capacidade de ativação quando considerados os dados obtidos com a ponta do aparelho fotopolimerizador distanciada do sensor de análise. Houve correlação positiva entre o custo do aparelho e sua capacidade de colimação. Conclusões: a fonte de luz empregada pouco influenciou o GC na subsuperfície. Por outro lado, o GC na profundidade de 4mm foi dependente da fonte empregada quando utilizadas as resinas bulk-fill de consistência regular. O comportamento da resina Surefill SDR foi homogêneo em toda profundidade e não dependente da fonte de luz empregada. Foi observada correlação positiva entre capacidade de ativação e colimação da fonte de luz (a) e capacidade de colimação e custo da fonte de luz (b).
Buscando novos rumos para o ensino da Dentística no Brasil.
Authors: Gonçalves Silvia Alencar
Published: April 2024

Em junho, realizamos o 23º encontro do Grupo Brasileiro de Professores de Dentística, no Hotel Prodigy Santos Dumont, no Rio de Janeiro. Nosso objetivo era um congresso que privilegiasse tanto a clínica quanto a pesquisa e, principalmente, o ensino da Dentística. Não era tarefa fácil; foram muitas reuniões, discussões e dúvidas. Muita ansiedade e medo de realizar um evento dessa importância aqui no Rio, num momento tão delicado que o estado vive.
Good Governance in International Relations: Integrity Management and Locality in Nasrafa Painting Fabric
Authors: Susiatiningsih Rr. Hermini Susiatiningsih , Faizal Alfian Muhammad
Published: April 2024

In the era of globalization, product internationalization is crucial for a company to reach the global market. The success of local businesses in reaching international markets needs to be supported by the involvement and collaboration of various actors. This research offers a unique insight into painted fabrics, an innovation of batik cloth as an original identity and cultural heritage of Solo (Central Java), which is a relatively new commodity that potentially penetrates international market. This study aims to examine and analyze the efforts of Nasrafais painting in Jebres Solo to penetrate the global market by exercising good governance and fostering collaborative relationships among various actors in multitrack diplomacy.  As one of the producers of painting fabric, Nasrafa has implemented local values and, as a result, earns prestigious national awards and grows foreign buyers. This research used the qualitative method, collecting primary data through interviews and discussing the collaborative effort between government, local business, and society in international relations, especially in the application of Good Governance. The results showed that the success of the export business was driven by massive, structured support from the government, corporations, and local citizens. An optimal, collaborative system can help establish the right conditions for industries to build domestic and international cooperation. This system is reflected in the production of Nasrafa painting fabric, indicating that the implementation of good governance can support multi-track diplomacy to accelerate the development and cooperation among actors in developing countries.
The Paradox of Public Service Innovation amid Regional Autonomy in Indonesia
Authors: Santoso R. Slamet , Warsono Hardi , Sunu Astuti Retno , Hayu Dwimawanti Ida
Published: April 2024

Law No. 23/2014 on the Local Government aims at fostering local governments in the country to nurture a culture of innovation to improve the quality of public services. This research attempts to discover paradoxes in the Surakarta City Government related to regulations governing local governments in Indonesia in developing public service innovation. This study uses a qualitative methodology with descriptive analysis related to the paradoxical evidence of public service innovation capacity in the Surakarta City government. Data were collected through in-depth interviews, observations, and literature studies of reputable journals. Furthermore, interviews were conducted with resource persons, from top management leaders to innovation actors, with a total of ten people. We utilised the analysis framework of Public Sector Innovation Capacity Management by Kim and Lee to analyse the results. We used SWOT analysis to devise a public service innovation capacity management strategy in Surakarta City. The results prove that the Surakarta City government has different characteristics in developing public service innovation. However, there is a paradox, which is a contradiction in the course of the local government in general. This paradox is evident in two main phenomena. First, there were no particular government regulations. Second, regional apparatus organisations (OPD) practice less collaborative mechanisms. By contrast, we found that entrenched innovation DNA and an external driver of innovation support the creation of public service innovations in the Surakarta City Government.
Bibliometric Analysis of Sociological Research on Artificial Intelligence
Authors: Purnomo Agustina Multi
Published: April 2024

This research aims to identify potential areas for future sociological research related to artificial intelligence (AI). The study used bibliometric analysis methods and the VosViewer pro- gram to process data. The data analyzed included 31 articles related to "sociology" and "artificial intelligence," and 1,277 articles pertinent to "social" and "artificial intelligence," all published on ScienceDirect between 2003 and 2023. Network visualization, overlay, and density analysis were used to process the data. This revealed that current sociological re- search on AI only covers five topics - artificial intelligence, sociology, technology, affects, and artificial intelligence. However, social research on AI has identified 100 topics across five datasets, with almost all research being conducted within the past decade. It is noteworthy that "sociology" is not among these 100 topics. However, these 100 topics have the potential to become sociological research subjects by applying sociological principles. The research findings suggest that sociologists can publish their scientific documents in 3,800 journals and books published by Elsevier, indicating a high probability of acceptance. Furthermore, the topics can be framed from a sociological perspective, thus providing greater insight on the subjects and potentially opening up the door to more publications by the sociologists.
La construction identitaire et le principe d’altérité. La Pologne comme l’Autre dans le discours de la presse écrite quotidienne en France
Authors: Biardzka Elżbieta , Paskart Patrycja
Published: April 2024

This study aims to show how the principle of otherness emerges in the discourse of the national written press in France. We  consider that in the media, the Other is Poland, whose social meaning, stored in    the collective memory, embraces the extremely negative traits of difference and threat. The judgment    of otherness relates to four components of this meaning. Firstly, Poland is perceived as an object whose location is indefinite and undecided. Secondly, it is strange due to its excessive, aggressive and dangerous Catholicism. Thirdly, it harms France and the common European project. Finally, it constitutes an eco- nomic threat.
Charlotte Appel, Nina Christensen och M.O. Grenby (red.), Transnational Books for Children 1750–1900
Authors: Svahn Elin
Published: April 2024

Review/Recension
Pia Maria Ahlbäck, Jouni Teittinen och Maria Lassén-Seger (red.), Nordic Utopias and Dystopias: From Aniara to Allatta!
Authors: Brudin Borg Camilla
Published: April 2024

Review/Recension
Stimulating thyrotropin receptor antibodies in early pregnancy
Authors: Uldall-Torp Nanna Maria , Andersen Lærke , Kim Hannah Jaekyung , Bruun Niels Henrik , Karmisholt Jesper , Andersen Stig , Andersen Stine Linding
Published: April 2024

Objectives

Thyrotropin-receptor antibodies (TRAb) are used to diagnose Graves’ hyperthyroidism in pregnant women. Bioassays provide a measure of thyrotropin-receptor stimulatory antibodies (TSI) specifically. The objective was to measure TSI in pregnant women for establishment of a pregnancy-specific cut-off and comparison with immunoassay measurements of TRAb.

Methods

The retrospective Danish study was performed within the North Denmark Region Pregnancy Cohort (2011–2015) that includes stored biobank samples from early pregnancy (median week 10) with immunoassay measurements of thyroid function parameters and TRAb. TSI were measured in the same samples using the Turbo TSI bioassay (Quidel/Ortho-Clinical Diagnostics) with a recommended cut-off of 0.0241 IU/L in non-pregnant adults. A pregnancy-specific TSI cut-off (95-percentile) was established using Regression on Order Statistics.

Results

The established TSI cut-off was 0.0418 IU/L (95 % CI: 0.0417–0.0419). Among women with early pregnancy hyperthyroidism (n=438), 43 women (9.8 %) were TSI positive using the established cut-off, and these women had lower TSH (median 0.008 mIU/L) compared to women with TSI levels below 0.0241 (median TSH 0.040 mIU/L) or in the range from 0.0241 to 0.0418 (median TSH 0.033 mIU/L). Among the 438 women with early pregnancy hyperthyroidism, 22 women were positive for TSI and TRAb, 388 were negative for both, and 28 women were positive for either TSI or TRAb.

Conclusions

This is the first study on TSI measurements in a large cohort of early pregnant women. A pregnancy-specific cut-off for TSI was established and agreement in the classification with immunoassay measurements of TRAb was seen in 94 % of cases.
Synthesis and characterization of ethylenediamine-modified F-44 phenolic epoxy fiber
Authors: Wu Juan , Jiao Mingli , Wang Hao , Li Keke , Yang Muen , Li Pengyu , Yang Kai
Published: April 2024

F-44 phenolic epoxy fibers were produced through high-temperature dry spinning utilizing F-44 phenolic epoxy resin as the base material, combined with n-butanol and ethylenediamine (EDA) as the curing agent. The fibers were subsequently analyzed for their structural, thermal stability, microstructural, and mechanical properties using techniques such as Fourier transform infrared spectroscopy, micro-infrared imaging, thermogravimetric analysis, nuclear magnetic resonance, scanning electron microscopy, and fiber strength testing. The limitations of phenolic resins, including high brittleness, poor toughness, and low elongation at break, restrict their potential applications, necessitating modifications to broaden their utility. Research findings indicate that modifying EDA induces a ring-opening reaction of epoxy groups, thereby enhancing the resin’s structure and improving the thermal stability and mechanical properties of fibers. The thermal stability and mechanical strength of the fibers were optimized at an EDA concentration of 2.0 wt% and curing time of 30 min, resulting in a tensile strength of 105 MPa and an elongation at break of 27.6 %.
The effect of osteopathic manipulative treatment on quality of life in patients with cardiac implantable electronic devices
Authors: Nikakis Jacqueline , Tale Ermin , Malkov Denis , Arora Uddampreet S. , Keys Jordan , Li To Shan , Yao Sheldon C. , Cohen Todd J.
Published: April 2024

Context

Osteopathic manipulative treatment (OMT) has been demonstrated to have an effect on the autonomic nervous system, which may have antiarrhythmic effects. The effects of OMT in patients with cardiac implantable electronic devices (CIEDs) have not previously been reported. This study investigated the impact of OMT on quality of life (QOL) in this patient population.

Objectives

The purpose of this study is to investigate the effects of OMT on QOL in CIED patients.

Methods

Subjects with CIEDs were recruited into a double-blind randomized controlled institutional review board (IRB)-approved clinical trial (ClinicalTrials.gov ID: NCT04004741) and randomized to OMT or light touch (control) groups. Subjects received a one-time intervention, performed by board-certified neuromusculoskeletal medicine (NMM) and osteopathic manipulative medicine (OMM) physicians. The OMT protocol utilized techniques including myofascial release, rib raising, facilitated positional release (FPR), and osteopathic cranial manipulative medicine. Subjects’ QOL was assessed immediately preceding intervention and one-month postintervention utilizing the Research ANd Development (RAND) 36-Item Short Form Health Survey (SF-36, eight parameters). Groups were compared utilizing unpaired t tests; α=0.05.

Results

Forty-two subjects were enrolled, with four lost to follow-up, which resulted in 19 OMT and 19 control subjects for analysis. Of the eight QOL parameters, two showed significant improvement with OMT: role limitations due to physical health (p=0.001) and pain (p=0.003).

Conclusions

This study demonstrates the potential for QOL improvement in CIED patients. Specifically, subjects in the OMT group reported an improvement in activities of daily living as well as a decrease in overall pain, including pain interfering with work. Additional research is necessary to further understand the physiologic effects of OMT, including its effects on arrhythmias, in CIED patients.
Leaving one’s mark: self-authorized commemorative practices in a rural semiotic landscape
Authors: Reershemius Gertrud K.
Published: April 2024

This study introduces the concept of “self-authorized commemorative practices” to the analysis of semiotic landscapes. It aims to draw attention to commemorative practices by which individuals assert their presence within the semiotic landscape, beyond the influence of powerful authorities that typically determine the visible commemorative aspects of public space. The multimodal practices employed include the use of language, images and artefacts, and their emplacement in the semiotic landscapes. The study is based on two complete photographic inventories of all signage in public space in a rural community in northwest Germany, taken over a ten-year period, in addition to more than twenty years of participant observation. The findings reveal layers of self-authorized commemorative practices, often concealed in plain sight but discernible to the trained eye, interwoven with the local narratives associated with the semiotic landscape. Individuals, through their own means, leave lasting marks that commemorate their existence, achievements, deceased loved ones, or social traditions. These self-authorized practices contribute to the rich tapestry of the semiotic landscape, challenging and expanding our understanding of commemoration beyond the influence of traditional authorities.