bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisa Pemanfaatan QR Code Terhadap Pengembangan Bahan Ajar Berbasis TPACK dan Moderasi Beragama
Authors: Himayatul Bariroh Shofia , Sabarudin
Published: July 2023

This study aims to analyze TPACK-based teaching materials by using the QR Code as a source of quotations in class. This study uses a type of quantitative research. The results of the study show that utilizing the QR Code as a source of quotations greatly influences students' understanding of the courses they take, especially in religious moderation courses. It can be seen from the calculations using SPSS that all components significantly affect the success of integrating TPACK. That is, the components of TPACK have a large impact on learning. The component that has a significant influence is TCK (0.529) and the one that has less significant influence is the CK component (0.152).
PENGARUH KOMPETENSI PROFESIONAL GURU DAN MOTIVASI BELAJAR TERHADAP HASIL BELAJAR SISWA PADA MATA PELAJARAN PAI DI SD NEDERI NO. 12 PULAU PAMALIKANG DESA SABARU KECAMATAN LIUKANG KALMAS KABUPATEN PANGKAJENE DAN KEPULAUAN
Authors: M Masmur
Published: July 2023

The objectives of this study were 1) To determine the effect of teacher professional competence on student learning outcomes in grade V at SD Negeri No. 12 Pamalikang Island Sabaru Village, Pangkajene Regency and Archipelago. 2) To determine the effect of student motivation on learning outcomes of class V students at SD Negeri No. 12 Pamalikang Island, Sabaru Village, Liukang Kalmas District, Pangkajene Regency and the Archipelago. 3) To determine the effect of teacher professional competence and student learning motivation together on the learning outcomes of fifth grade students at SD Negeri No. 12 Pamalikang Island Sabaru Village, Pangkajene Regency and Archipelago. The type of research used is correlational quantitative which aims to determine whether or not there is an influence between the two variables to be measured. Total population of 38 students consisted of class III to class V SD Negeri No.12 Pamalikang Island. The sampling technique used was saturated / census samples.Based on the results of the study showed that 1) the professional competence of teachers has a positive and significant effect on student learning outcomes in Islamic Education subjects at SD Negeri No. 12 Pamalikang Island, Sabaru Village, Liukang Kalmas District, Pangkajene Regency and the Archipelago. 2) Learning motivation has a positive and significant effect on student learning outcomes in Islamic Education subjects at SD Negeri No. 12 Pamalikang Island, Sabaru Village, Liukang Kalmas District, Pangkajene Regency and the Archipelago. 3) Teacher professional competence and learning motivation simultaneously have a positive and significant effect on student learning outcomes in Islamic Education subjects at SD Negeri No. 12 Pamalikang Island, Sabaru Village, Liukang Kalmas District, Pangkajene Regency and the Archipelago
PEMIKIRAN ANREGURUTTA HAJI DAUD ISMAIL TENTANG AKHLAK MANUSIA
Authors: Jannah Sitti Riadil
Published: July 2023

Anregurutta Haji Daud Ismail's thoughts about human morality can be understood that morality as a value system that characterizes human life is one of the vessels in building a transcendental relationship between al-Khalik and His creatures. In this context, it can be seen that there are two moral dimensions in the thinking of this Bugis-born charismatic cleric, namely the esoteric dimension on the one hand and the exoteric dimension on the other. Humans in their lives are very likely to commit various sins which basically they wrong themselves. Therefore, humans must continue to improve their morals by making istighfar or repenting to the God. In the thought of Anregurutta Haji Daud Ismail, human morals are divided into morals towards Allah SWT. and morals to fellow human beings with various forms of elaboration which are described in detail in his commentary, namely al-Munir.
A pandemia da Covid-19 e as mudanças no cenário educacional: os desafios docente e discente na formação médica
Authors: Silveira Jéssica Barreto da , Loureiro Paula Rodrigues Andrade da Cunha , Amorim Bianca Débora de Macêdo , Magalhães Dandara Victoria Rocha , Costa Juliana Leles , Dobrachinski Leandro
Published: July 2023

Objetivo: Analisar o impacto da pandemia da COVID-19 no cenário educacional, apresentando os principais desafios enfrentados pelos docentes e discentes na formação médica. Métodos: Trata-se de uma revisão de literatura do tipo integrativa, cuja coleta de dados foi realizada nas bases de dados National Library of Medicine (PubMed), Scientific Eletronic Library Online (SciELO), Biblioteca Virtual em Saúde (BVS), utilizando como critérios de inclusão e exclusão os seguintes descritores: “COVID-19”, “formação médica” e “docentes”, “discentes”, “ensino e aprendizagem” Resultados: Após análise, verificou-se que a pandemia da COVID-19 gerou diversos impactos, sendo o principal a suspensão das aulas presenciais, contudo, as barreiras na educação médica nesse período podem ainda ser divididas em quatro níveis: (1) barreiras das instituições e ensino; (2) infraestrutura e tecnologia; (3) barreiras estudantis e (4) barreiras vivenciadas pelos educadores. Considerações finais: Apesar dos desafios impostos pelo ensino a distância, a tecnologia abriu um caminho flexível ao modelo clássico das aulas presenciais por meio da adaptação baseada no ensino remoto, porém, a maior limitação diz respeito a qualidade das aulas práticas, corroborando que o ensino a distância ainda representa um grande desafio para adquirir habilidades clínicas adequadas.
Desafios e necessidades de pessoas com Transtorno do Espectro Autista no mercado de trabalho
Authors: Borba Maria Eduarda Cavalcanti de Melo , Melo Maria Clara Rodrigues de , Berto Maria Eduarda do Nascimento Paiva , Sabino Mariana Ramalho Braga , Sabino Ingrid Ramalho Braga , Lucena Laila Queiroga , Maia Alisson Fernandes Lobo , Lúcio Ana Silvia Suassuna Carneiro , Araújo Izabelle Cristine Faustino de , Fonsêca Rachel Cavalcanti
Published: July 2023

Objetivo: Identificar quais os desafios e necessidades das pessoas autistas, adentrando nas possibilidades de intervenções de melhoria no mercado de trabalho. Métodos: Revisão integrativa, nos idiomas português e inglês sendo prevalente no inglês, pesquisado nas bases de dados eletrônicos biblioteca virtual de saúde (BVS), PUBMED e SciELO, elaborada no período de março a maio de 2023. Resultados: A análise foi feita diante de um total de 13 artigos selecionados, indicando que a observação da deficiência no mercado de trabalho como sendo a característica chave da pessoa com Transtorno do Espectro Autista (TEA) é o fator mais presente nos artigos. Considerações finais: A maioria os estudos contêm projetos e propostas para tornar a entrada e permanência das pessoas com TEA no mercado de trabalho algo mais igualitário e que ainda existem dificuldades como a falta de interesse por parte da equipe em se capacitar para acolher alguém diferente, as restrições que o autista tem em relação a convivência e a falha na capacitação dessa mão de obra diante de suas particularidades.
AXIOLOGICAL POTENTIAL OF ORTHODOX CULTURE
Authors: Гераськина О.А.
Published: July 2023

Рассматриваются ценностные установки православной культуры в аспекте понятийного ряда ценностей: «еловек и его жизнь», «семья», «Родина», «мир», «красота», «труд», «знание», «святыня». Приведенный анализ основывается на библейских текстах, святоотеческой литературе, трудах философов и педагогов.

The article examines the values of Orthodox culture in the aspect of the conceptual series of values: Man and his Life, Family, Motherland, Peace, Beauty, Labor, Knowledge, Holiness. The analysis is based on biblical texts, patristic literature, works of philosophers and educators.
МЕТОДЫ ОБРАБОТКИ БОЛЬШИХ ДАННЫХ В ЗАДАЧАХ ФИНАНСОВОГО КОНТРОЛЯ
Authors: Сушков В. М. , Леонов П. Ю.
Published: July 2023

С каждым годом увеличивается объем корпоративных данных, подлежащих анализу в рамках финансового контроля, вследствие чего актуальным является внедрение методов обработки больших данных в практику субъектов контроля. Целью исследования является разработка и апробация методов обработки больших данных в целях решения задач организаций государственного и частного сектора, проводящих мероприятия в области финансового контроля. В качестве методов исследования выбрано три наиболее перспективных и эффективных средств обработки больших данных, которые в то же время не требуют использования громоздкого математического аппарата или значительных компьютерных мощностей для их реализации, а именно статистический инструмент выявления искажений в финансовых данных закон Бенфорда, кластеризация методом К-средних и средства BI-системы Power BI. Результатом исследования является подтверждение результативности и эконо­мической эффективности рас­сматри­ваемых методов обработки больших данных, а также обоснование практической возможности их внедрения в качестве инструментов финансового контроля. Исследование проведено в студенческой Лаборатории финансовой разведки НИЯУ МИФИ.
STUDI DESKRIFTIP KARAKTER KEPEMIMPINAN PCM BUKATEJA DAN PCM KEJOBONG KABUPATEN PURBALINGGA
Authors: Harmianto Sri
Published: July 2023

The condition of the organizational activity of the Persyarikatan Muhammadiyah at the branch and sub branch level in Purbalingga Regency is very diverse, since there are Muhammadiyah Branches that are advanced but less active, Muhammadiyah branches that have many active Muhammadiyah Sub Branches, and there are also less active Muhammadiyah Branches with less active Muhammadiyah Sub Branches. Interestingly, there are Muhammadiyah Branches which are less active, but have many active Muhammadiyah Sub Branches. In this study, the leadership styles of the advanced Muhammadiyah Branches were investigated, namely the Muhammadiyah Branch Leaders (PCM) Bukateja and PCM Kejobong. Furthermore, the leadership style of the advanced Muhammadiyah Branch can be a guide for the relatively passive sub branches of Muhammadiyah. From the results of the study, it was found that the most dominant types of leadership were the Chairman of the Muhammadiyah Regional Leadership (PDM), the Head of the Branch and Sub Branch Development Institute (LPCR), and the Head of the Branch, namely the charismatic leadership type, then the democratic leadership type, the leadership type that likes development, and transformational leadership type. Thus, the recommendation is the type of leadership in the Persyarikatan Muhammadiyah Purbalingga Regency needs special attention because currently it is mostly held by the "old generation" who were chosen because they were charismatic. This makes regeneration difficult, unless leadership regeneration has been programmed from an early age.
Analisis Faktor Yang Mempengaruhi Keputusan Wisatawan Untuk Berpariwisata Kepantai Anyar
Authors: Razani Nurma Arafah
Published: July 2023

Tourism is a journey undertaken for the sake of entertainment either individually or in groups. Nature tourism includes objects and activities such as recreation and tourism by utilizing natural resources and their ecosystems, both in their natural forms and in combination with man-made ones. The purpose of nature tourism is none other than for recreation, learning the uniqueness of an area that is addressed through tourist attractions, getting peace of mind and can also be used for self-development. Banten is one of the areas with a variety of tourism places that are abundant and always crowded with visits during national holidays and regular holidays. Banten has many beach objects which are very suitable as places for tourism. The Banten area has great potential in tourism on beach objects, especially the New Beach, which is one of the best tourism objects in the Banten area. There are various reasons why tourists should visit Anyar Beach. The author will describe various good reasons for tourists to make Anyar Beach the best place for entertainment in their spare time, whether with family, friends or themselves.
Strategi Pemasaran Restoran Cepat Saji Domino’s Pizza Cabang Cilegon Dalam Meningkatkan Penjualan
Authors: Rajeba Halizsa Nadia
Published: July 2023

Strategy is an action that is incremental (always increasing) and continuous and is carried out from the point of view of what customers expect in the future. In this study, focused on "how domino's pizza marketing strategy can increase product sales". This study suggests a problem formulation, namely how the domino's pizza marketing strategy is to increase product sales. This type of research is qualitative descriptive, using informants to conduct interviews and observations using a case study approach. The data source used is primary data, namely information that comes from direct observation of the research location after making observations and interviews. Meanwhile, secondary sources are data obtained from documentation or literature study to complement primary data.
The results of this study are Domino's Pizza is a restaurant that implements two marketing systems, both online and offline, to increase domino's pizza enthusiasts to hold promos and discounts without any big days and generate profits for the company, domino's pizza also always pays attention. the quality of its products, the existence of a complete payment system can make it easier for consumers to transact and domino's staff also serve friendly customers in order to create a good and positive experience.
Komunikasi Pemasaran Melalui Pemanfaatan Media Sosial Instagram Sebagai Media Informasi
Authors: Pitasari Dwi Nurina
Published: July 2023

Pulau Dua Nature Reserve and Sangiang Island Natural Park are islands that have a wealth of natural resources that are very beautiful. BKSDA Region 1 Serang disseminates information and activities on the island by utilizing Instagram @rkw2_serangjabar according to marketing communication purposes. This study uses a qualitative approach. The data sources used are primary and secondary data. The informant shopping technique is using a purposive sampling technique. Data collection techniques in research are through in-depth interviews, observation, and documentation. The results showed that the use of Instagram was supported by information motives, social interaction motives, entertainment motives. The conclusion of this study is that information about Pulau Dua Nature Reserve and Sangiang Island TWA is spread through verbal cues, namely content made on Instagram @rkw2_serangjabar so that information exchange occurs. and build an interesting impression that can be accepted by the public or followers.
Pengelolaan Objek Wisata Pemandian Air Panas Cipanas Pandeglang Banten Menurut UU No 10 Tahun 2009 Tentang Kepariwisataan Dalam Mewujudkan Kesejahteraan Masyarakat
Authors: Chandra Indriarti
Published: July 2023

Indonesia is one of the countries where almost every region has a complete tourist attraction, namely natural beauty, flora, fauna and historical heritage. One of the tourism destinations in Indonesia which has its own potential and attractiveness is Pandeglang Regency, Banten. This study aims to determine the Management of Cipanas Hot Spring Tourism Objects in Developing Tourism Objects According to Law Number 10 of 2009 concerning Tourism and the Impact of Tourism Object Development on the Welfare of the Surrounding Community. In conducting research, the authors use qualitative methods that collect data from observations, interviews, literature studies. The results of research on the Management of Cipanas Pandeglang Banten Hot Spring Tourism Objects According to the Perspective of Islamic Law and Law no. 10 of 2009 concerning Tourism in Realizing Community Welfare, namely: Management at the Cipanas tourist attraction itself in terms of nature conservation applies a zoning system in terms of land management.
HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells
Authors: Zhang Yanan , Huang Junjun , Yan Lingyan , Jia Rong , Guo Jihua
Published: July 2023

Background: RUNX2 (Runt-related transcription factor 2) acts as a key regulator in the odontogenic differentiation of human dental pulp stem cells (hDPSCs). Moreover, the inclusion of exon 5 is important for RUNX2 function. Our previous study showed that Y-Box Binding Protein 1 (YBX1) promoted RUNX2 exon 5 inclusion and mineralization of hDPSCs. However, the regulatory mechanism of RUNX2 exon 5 alternative splicing needed further exploration. Methods: The expression level of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) during the odontogenic differentiation of hDPSCs was analyzed by RT-PCR and Western blot. The roles of hnRNP A1 in the alternative splicing of RUNX2 exon 5 and the odontogenic differentiation of dental mesenchymal cells were analyzed by gain- and loss-of-function experiments. Results: Surprisingly, we found an alternative splicing factor, hnRNP A1, which had an opposite role to YBX1 in regulating RUNX2 exon 5 inclusion and odontogenic differentiation of hDPSCs. Through gain- and loss-of-function assay, we found that hnRNP A1 suppressed the inclusion of RUNX2 exon 5, resulting in the inhibition of odontoblastic differentiation. The overexpression of hnRNP A1 can inhibit the expression of ALP (alkaline phosphatase) and OCN (osteocalcin), and the formation of mineralized nodules during the odontogenic differentiation of both hDPSCs and mouse dental papilla cells (mDPCs), whereas the opposite results were obtained with an hnRNP A1 knockdown preparation. Conclusions: The present study indicated that hnRNP A1 suppressed RUNX2 exon 5 inclusion and reduced the odontogenic differentiation ability of hDPSCs and mDPCs.
Power and Precision in the Public Health Economy
Authors: Williams Christopher
Published: July 2023

IntroductionSteven Lukes’ second edition of Power: A Radical View appears to have little import for public health theory and practice. Its academic discussion is well-cited and well-written, but dense and conceptual. lts practice-based reasoning is wanting. Lukes admitted as such, “And yet, among those who have reflected on the matter, there is no agreement about to how to define it, how to conceive it, how to study it and, if it can be measured, how to measure it. There are endless debates about such questions, which show no sign of imminent resolution, and there is not even agreement about whether all this disagreement matters.”1On the other hand, Public Health Liberation seeks transdisciplinary synthesis to elucidate and affect the Public Health Economy. It is imperative to sift through the concepts and theories in Lukes’ Power to fulfill the mission of our transdiscipline. As such, here are five critiques of this discourse to build upon the disciplinary foundation of Public Health Liberation. This discussion is meant to bridge the core tenets of PHL, as discussed in our inaugural manuscript. First, we discuss power in the context of Steven Lukes’ Power: A Radical View, then provide five takeaways for thinking about the Public Health Economy.
MENINGKATKAN HASIL BELAJAR PKN DENGAN METODE DISCOVERY LEARNING
Authors: Kustiyono Kustiyono
Published: July 2023

“discovery learning adalah suatu cara mengajar yang melibatkan peserta didik dalam proses kegiatan mental dimana peserta didik dibimbing untuk berusaha mensintesis, menemukan, atau menyimpulkan prinsip dasar dari materi yang sedang dipelajari”. Discovery merupakan suatu rangkaian kegiatan pembelajaran melibatkan secara maksimal seluruh kemampuan peserta didik untuk mencarai dan menyelidiki secara sistematis, kritis, dan logis, sehingga mereka dapat menemukan sendiri pengetahuan, sikap dan ketrampilan sebagai wujud adanya perubahan perilaku. Dapat peneliti simpulkan bahwa metode discovery learning adalah metode yang merangsang peserta didik untuk menemukan sendiri jawaban dari bahan pelajaran yang diberikan oleh guru,dan penggunaan metode alat peraga yaitu sapu lidi untuk menarik minat peserta didik dalam pembelajaran yang bertujuan untuk membangkitkan semangat belajar peserta didik terhadap mata pelajaran PKN dan terwujudnya nilai KKM yang memuaskan. Pembelajaran ini melibatkan peserta didik secara aktif untuk menemukan sendiri informasi atau jawaban dengan melibatkan guru sebagai pembimbing. Dengan menggunakan metode ini peserta didik diharapkan mampu sebagai seorang penemu tapi juga sebagai pencipta, dimana peserta didik dituntut untuk memiliki pemahaman terhadap suatu informasi dan kemudian dapat menyajikan secara utuh.Peserta didik sebagai peran utama harus berperan aktif dalam pembelajaran discovery learning, karena tanpa adanya antusias dan keaktifan peserta didik maka pembelajaran yang diharapkan tidak akan tercapai. Model pembelajaran discovery learning memilki karakteristik yang menjadi ciri khas dari pada model pembelajaran yang lainnya. Hal ini yang memebuat model discovery learning banyak diterapkan di tingkat sekolah dasar dengan pertimbangan kesesuaian dengan tujuan pemebelajaran.
Evaluating the performance of personality-based profiling in predicting physical activity as an external outcome
Authors: Katahira Kentaro , Takano Keisuke , Oba Takeyuki , Kimura Kenta
Published: July 2023

Classifying individuals based on personality and other characteristics is a common statistical approach used in marketing, medicine, and social sciences. This approach has several advantages: it improves the simplicity of data, helps data-driven decision-making, and guides intervention strategies such as personalized care. On the other hand, continuous variables are often used to classify individuals, meaning that dimensional information is reduced to several discrete classes (of individuals) and thus much information is lost through this process. Although the loss of information may be practically or pragmatically acceptable, how much information is lost and what influence this decision has on predicting external outcomes has not been systematically investigated. Therefore, in this study, we examined the predictive performance of the classification approach compared with the dimensional approach by analyzing survey data obtained from approximately 20,000 individuals concerning physical activity and psychological traits, including the Big Five personality traits. First, we classified individuals based on the dimensional data of their psychological traits and obtained several different cluster solutions. Second, these clusters were used to predict the levels of physical activity (i.e., the classification approach), which were then compared with the predictions made by the raw dimensional scales of psychological traits (i.e., the dimensional approach). The results showed that the four-cluster solution, which was supported by the standard criterion for determining the number of clusters, achieved no more than 60% explanatory power of the dimensional approach. To achieve a comparable prediction accuracy, the number of clusters must be increased to at least 20. These findings imply that the cluster solution suggested by the conventional statistical criteria may not be optimal when clusters are used to predict external outcomes.
Comparative Analysis of the Implementation of HR Accounting on Financial Performance at PT. Bank Syariah Indonesia Tbk
Authors: Junaidi Listya Devi , Mulyani Sri
Published: July 2023

Human resource accounting has emerged as a result of accounting standards' failure to give management and investors pertinent information. This study aims to compare PT. Bank Syariah Indonesia Tbk's financial performance ratio (profitability ratio) before and after the adoption of human resource accounting. The research method used is descriptive experimental research method. The data used is the company's annual report data for 2020 and 2021. Furthermore, the data is calculated using historical cost data analysis techniques and profitability ratios. The findings from this study indicate an increase in total assets and total equity in the statement of financial position after simulating the application of human resource accounting. This is due to the total value of the net human resource investment that occurs in each year of the existing implementation simulation statement of financial position, so that a new human resource asset account appears in the asset position and retained earnings adjustment in the equity position. While the results of a comparative analysis of financial ratios using return on assets, return on equity, asset utilization, equity multiplier and profit margin show a decline in 2021 but the numbers are relatively small.  In future research it is expected to add years of research and add other financial ratios so that the results obtained are even better.
URGENSI PENERBITAN PERPPU KPK TERHADAP KOMITMEN PEMBERANTASAN KORUPSI DI INDONESIA
Authors: Daulay Anis Putri Miranda
Published: July 2023

Revisi Undang-Undang Nomor 30 Tahun 2002 tentang Komisi Pemberantasan Korupsi (KPK) menimbulkan polemik dan desakan dari masyarakat kepada Presiden agar membentuk Perpu KPK sebagai tindak lanjut dari dibentuknya UU Nomor 19 tahun 2019. Penelitian ini merupakan penelitian hukum normatif dengan pendekatan perundang-undangan, data primer dan sekunder bersumber dari studi kepustakaan, adapuntujuan penelitian ini adalah melihat urgensi dibentuknya perppu oleh Presiden, dan hasil penelitian menunjukkan bahwa Perppu tidak dapat dibentuk sebab tidak memenuhi beberapa kriteria yang ditetapkan melalui Putusan Mahkamah Konstitusi No/138/PUU-VII/2009.
PENGARUH MARKETING MIX DAN KUALITAS PELAYANAN TERHADAP KEPUASAN KONSUMEN MUJIGAE RESTO, BEKASI
Authors: Satria Budi , Untari Dhian Tyas , Khasanah Fata Nidaul
Published: July 2023

Penelitian ini bertujuan untuk mengetahui apakah marketing mix berpengaruh pada kepuasan konsumen mujigae resto, apakah kualitas pelayanan berpengaruh pada kepuasan konsumen mujigae resto, dan apakah keduanya berpengaruh pada kepuasan konsumen mujigae resto. Hasil yang didapat penulis dalam penelitian ini yaitu untuk variabel marketing mix karena nilai t hitung lebih besar dari t tabel (4,54 > 1,6648) dan nilai signifikansi lebih kecil dari 0.05 (0.000 < 0.05), dapat ditarik kesimpulan bahwa marketing mix pengaruh yang signifikan terhadap kepuasan pelanggan, untuk variabel kualitas pelayanan karena nilai t hitung lebih besar dari t tabel (5,99 > 1,6648) dan nilai signifikansi lebih kecil dari 0.05 (0.000 < 0.05), dapat ditarik kesimpulan bahwa kualitas pelayanan pengaruh yang signifikan terhadap kepuasan pelanggan, dan untuk pengaruh keduanya karena nilai F hitung lebih besar dari F tabel (73,193 > 3,11), dan nilai signifikansi 0.000 < 0.05 dapat ditarik kesimpulan bahwa marketing mix dan kualitas pelayanan berpengaruh positif dan simultan terhadap kepuasan pelanggan.
Analisis Cluster K-Means dengan Metode Elbow untuk Menentukan Pola Penjualan Produk Traffic Room Summarecon Mal Bekasi
Authors: Prasetya Ajie , Salkiawati Ratna , D. Alexander Allan
Published: July 2023

Ajie Prasetya. 201910225132. Analisis cluster k-means dengan metode siku untuk menentukan pola penjualan produk traffic room summarecon mal bekasi. Bekasi: Fakultas Ilmu Komputer. Universitas Bhayangkara Jakarta Raya. 2023

                                           

Strategi penjualan yang efektif dalam bisnis ritel fashion sangatlah penting untuk menentukan keberhasilan perusahaan atau toko. Seperti toko Traffic Room yaitu toko ritel fashion vintage yang menjual berbagai macam produk. Walaupun banyaknya produk yang di jual, toko ini belum memanfaatkan data penjualan untuk menentukan pola penjualan produk sehingga menimbulkan dampak negatif seperti masih banyak produk yang kekurangan persediaan dan produk tidak terjual dengan target yang sudah ditentukan. Maka tujuan dari penelitian ini untuk mengetahui pola penjualan produk agar bisa memperbaiki persediaan produk. Untuk mengatasi permasalahan ini, analisis yang digunakan yaitu algoritma K-Means untuk mencari pola penjualan produk dibantu dengan metodesiku dalam menentukan cluster yang optimal. Serta yang menjadi alur dalam proses penelitian ini yaitu metode CRISP-DM dengan langkah-langkahnya yaitu pemahaman bisnis, pemahaman data, persiapan data, pemodelan, evaluasi dan penyebaran . Hasil dari penelitian ini mendapatkan 4 cluster yaitu cluster 2 atau sangat laris ada 2 produk, cluster 3 atau laris ada 5 produk, cluster 1 atau cukup laris ada 5 produk dan cluster 4 atau kurang laris ada 3 produk. Hasil evaluasi mendapatkan nilai Sum of Square Error (SSE) optimal yaitu 594.366,733 atau 65,5%. Dari hasil evaluasi artinya kinerja algoritma K-Meansyang digunakan sudah baik.

 

Kata Kunci : Pola Penjualan Produk, Algoritma K-Means , Metode Elbow , CRISP-DM, Sum of Square Error (SSE)
Hemodynamic Effects of Oxytocin when Given as Bolus or Slow Intravenous Infusion During Cesarean Section
Authors: Begum Nasima , Khanum Tahamina , Khatun Rahima , Rahman Nelufa Tahera
Published: July 2023

Background: Oxytocin is a uterotonic drug with profound haemodynamic effects. The effects of oxytocin on women undergoing cesarean section include tachycardia, hypotension and decreased cardiac output. These can be sufficient to cause significant compromise in high risk patients.
Objective: This study aims to find out a simple way to decrease these risks without compromising the therapeutic benefits such as decreasing bleeding after delivery and uterine contraction.
Materials and Methods: We recruited 60 women undergoing cesarean section. The subjects were randomly divided into two groups, 30 subjects per group, randomly selected by blind envelope method. Group A: parturient received 5 IU bolus (approximately over 2 seconds). Group B: parturient received 5 IU oxytocin IV slow infusion (diluted with 10 mL distilled water) over 2 minutes.
Results: A significant increase in heart rate and fall in blood pressure in the group where oxytocin was given IV bolus compared to the slow IV infusion group. There were no differences in the estimated blood loss and uterine contraction between the two groups.
Conclusion: The haemodynamic changes are more marked in the IV bolus than the slow IV infusion of oxytocin. Slower injection of oxytocin can effectively minimize the cardiovascular side effects without compromising the therapeutic benefits.
J Enam Med Col 2021; 11(2): 92-98
Application of a PM2.5 dispersion model in the Bangkok central business district for air quality management
Authors: Ratanavalachai Thammaluck , Trivitayanurak Win
Published: July 2023

Model simulations are conducted for fine particles diameter less than 2.5 microns (PM2.5) in the Chulalongkorn University area in the central business district of Bangkok, Thailand, where PM2.5 originating from road traffic is a recurring problem. For input to the American Meteorological Society/U.S. Environmental Protection Agency Regulatory Model (AERMOD), an hourly continuous vehicle type classified emissions inventory is developed based on local traffic observations and published emissions factors. The simulation accounts for advected-in PM2.5 by hourly measurements from upwind stations. The result reveals a hotspot location near a nearby expressway with PM2.5 concentration peaking at 1-h and 24-h averages of 344 and 130 μg m−3, respectively. Source contribution analysis of the annual average PM2.5 at this hotspot suggests that the expressway contributes approximately 32% of the total PM2.5. Meanwhile, at receptor points farther from the expressway, ground-level urban roads contribute only 17.5% roadside PM2.5 concentrations, the remainder coming from outside the modeled area. A different source contribution breakdown by vehicle type suggests that heavy-duty vehicles contribute up to 21% of annual average PM2.5 at a location near the expressway. At a roadside receptor point farther from the expressway, the top contributors are light-duty (9%) and heavy-duty vehicles (6%). Advected-in PM2.5 dominates the overall PM2.5 concentrations, accounting for 64%–99% depending on the receptor point. The model performance for 24-h average prediction is acceptable. A scenario study is also performed to compare the potential effectiveness of two PM2.5 abatement measures.
The deformation of marine snow enables its disaggregation in simulated oceanic shear
Authors: Song Yixuan , Burd Adrian B. , Rau Matthew J.
Published: July 2023

Understanding the effect of hydrodynamics on aggregate size and structure is key to predicting mass transport in the aquatic environment. Aggregation theory of particles is well established but our knowledge of deformation processes, biological bonding forces, and their effects on fragmentation of aquatic aggregates is still limited. To better comprehend fragmentation processes and adhesion forces we implemented breakup experiments with diatom and microplastic aggregates made in the laboratory. We captured a substantial number of events showing deformation and subsequent fragmentation of these aggregates in an oscillatory shear flow. Polystyrene and polyethylene aggregates showed distinct fragmentation strengths and provided comparative upper and lower limits to the biological bonding strength of the diatom aggregates. Additionally, we employed a force balance model to evaluate attractive interactions within clusters of particles using the Lagrangian stress history and morphology. We found that the fractal structures of aggregates led to a power law of breakup strength with size and that time-integrated stress governed the overall fragmentation process. We also found that the weakening of the aggregates through deformation with shear exposure enabled their disaggregation at very low shear rates typical of the ocean environment.
A (t, n) threshold protocol of semi-quantum secret sharing based on single particles
Authors: Zhou Ziyi , Wang Yifei , Dou Zhao , Li Jian , Chen Xiubo , Li Lixiang
Published: July 2023

Semi-quantum secret sharing is an important research issue in quantum cryptography. In this paper, we propose a (t, n) threshold semi-quantum secret sharing protocol, which combines the practicality of semi-quantum secret sharing protocols and the flexibility of (t, n) threshold quantum secret sharing protocols. Participants prepare and transmit single particles in a circular way, and then any t out of n participants can recover the secret according to Shamir’s secret sharing scheme. As quantum resources, single particles are easy to prepare. Furthermore, classical participants only need to possess the capability to prepare and insert particles. The security analysis shows our protocol has security against most attacks. Except decoy particles, all particles are useful to carry the secret message, so the efficiency of the proposed protocol can achieve 100%.
Magnesium supply alleviates iron toxicity-induced leaf bronzing in rice through exclusion and tissue-tolerance mechanisms
Authors: Rajonandraina Toavintsoa , Ueda Yoshiaki , Wissuwa Matthias , Kirk Guy J. D. , Rakotoson Tovohery , Manwaring Hanna , Andriamananjara Andry , Razafimbelo Tantely
Published: July 2023

Introduction

Iron (Fe) toxicity is a widespread nutritional disorder in lowland rice causing growth retardation and leaf symptoms referred to as leaf bronzing. It is partly caused by an imbalance of nutrients other than Fe and supply of these is known to mitigate the toxicity. But the physiological and molecular mechanisms involved are unknown.

Methods

We investigated the effect of magnesium (Mg) on Fe toxicity tolerance in a field study in the Central Highlands of Madagascar and in hydroponic experiments with excess Fe (300 mg Fe L-1). An RNA-seq analysis was conducted in a hydroponic experiment to elucidate possible mechanisms underlying Mg effects.

Results and discussion

Addition of Mg consistently decreased leaf bronzing under both field and hydroponic conditions, whereas potassium (K) addition caused minor effects. Plants treated with Mg tended to have smaller shoot Fe concentrations in the field, suggesting enhanced exclusion at the whole-plant level. However, analysis of multiple genotypes showed that Fe toxicity symptoms were also mitigated without a concomitant decrease of Fe concentration, suggesting that increased Mg supply confers tolerance at the tissue level. The hydroponic experiments also suggested that Mg mitigated leaf bronzing without significantly decreasing Fe concentration or oxidative stress as assessed by the content of malondialdehyde, a biomarker for oxidative stress. An RNA-seq analysis revealed that Mg induced more changes in leaves than roots. Subsequent cis-element analysis suggested that NAC transcription factor binding sites were enriched in genes induced by Fe toxicity in leaves. Addition of Mg caused non-significant enrichment of the same binding sites, suggesting that NAC family proteins may mediate the effect of Mg. This study provides clues for mitigating Fe toxicity-induced leaf bronzing in rice.
Urban health inequality in shifting environment: systematic review on the impact of gentrification on residents' health
Authors: Delong Sun
Published: July 2023

The impacts of changing neighborhoods, and the influence of neighborhood stability on residents' health have not received enough attention in the literature; one of the most important aspects is gentrification. Research on the impact of gentrification on residents' health has gradually increased in recent years, mainly from North America. Based on the guidelines of PRISMA 2020 and SCIE, 66 papers were included for analysis, six aspects of selected studies are discussed: the research design, theoretical framework, methods of analysis, definition and measurement of gentrification effects, and impact pathways. In general, most of the literature in this field can be seen as using an ecological research design, of which cross-sectional research accounts for a large proportion. The identified effects vary in their direction as well as strength due to difference in population, temporal, and geographical characteristics. Gentrification could affect health outcomes through the combination of economic, social, and physical environment factors. Existing research could be improved in the following aspects: (1) The definition and measurement of gentrification should be both generic and site-specific; Various measurement methods should be compared to enhance the robustness of the results. Furthermore, more consideration should be given to the impact of spatial issues; (2) As for health outcomes, it is suggested to expand the scope of the discussion of health outcomes and strengthen the biological explanation of the influencing mechanisms. It is also necessary to determine the research time points according to the characteristics of the incubation period of different diseases; (3) As for research design, applying longitudinal research design is more likely to improve the reliability; (4) Theoretical frameworks should be addressed to link the definition and measurement of gentrification, patterns of health outcomes, methodology and pathways.
Trajectory Optimization for Multi-Sensor Multi-Target Search and Tracking with Bearing-Only Measurements
Authors: Yang Xiwen , Yin Hang , He Shaoming , Xie Ye , Shin Hyo-Sang
Published: July 2023

This paper proposes a trajectory optimization approach for multi-sensor multi-target search and tracking using bearing-only sensors. Based on the framework of the joint integrated probabilistic data association (JIPDA) filter, the intensity of potential unknown targets is updated according to the trajectories of the UAVs. The performance indices for target search and tracking are constructed based on, respectively, the intensity of unknown targets in the search area and the tracking error covariance. A dimensionless criterion, evaluating the search and tracking performance, is formulated and leveraged as the objective function of the UAV trajectory optimization problem. Simulations were carried out in different search and tracking scenarios to demonstrate the effectiveness of the proposed approach.
Effect of Escin Alone or in Combination with Antifungal Agents on Resistant Candida glabrata Biofilms: Mechanisms of Action
Authors: Maione Angela , Imparato Marianna , Galdiero Marilena , Alteriis Elisabetta de , Feola Antonia , Galdiero Emilia , Guida Marco
Published: July 2023

Nowadays, the increase in antimicrobial-resistant fungi (AMR) is certainly a major health concern, and the development of alternative therapeutic strategies has become crucial. Natural products have been used to treat various infections, and their chemical properties contribute to the performance of their biological activities, such as antifungal action. The various virulence factors and mechanisms of resistance to antifungals contribute to making Candida glabrata one of the most frequent agents of candidiasis. Here we investigate the in vitro and in vivo activity of β-escin against Candida glabrata. The β-escin MICs were determined for a reference strain and two clinical isolates of C. glabrata. Furthermore, growth kinetics assays and biofilm inhibition/eradication assays (crystal violet) were performed. The differences in the expression of some anti-biofilm-associated genes were analyzed during biofilm inhibition treatment so that reactive oxygen species could be detected. The efficacy of β-escin was evaluated in combination with fluconazole, ketoconazole, and itraconazole. In addition, a Galleria mellonella infection model was used for in vivo treatment assays. Results have shown that β-escin had no toxicity in vitro or in vivo and was able to inhibit or destroy biofilm formation by downregulating some important genes, inducing ROS activity and affecting the membrane integrity of C. glabrata cells. Furthermore, our study suggests that the combination with azoles can have synergistic effects against C. glabrata biofilm. In summary, the discovery of new antifungal drugs against these resistant fungi is crucial and could potentially lead to the development of future treatment strategies.
A2AR Expression and Immunosuppressive Environment Independent of KRAS and GNAS Mutations in Pseudomyxoma Peritonei
Authors: Kusamura Shigeki , Busico Adele , Conca Elena , Capone Iolanda , Agnelli Luca , Lorenzini Daniele , Brich Silvia , Angelini Marta , Volpi Chiara Costanza , Trupia Desirè Viola , Lagano Vincenzo , Torelli Tommaso , Gloghini Annunziata , Baratti Dario , Guaglio Marcello , Milione Massimo , Deraco Marcello , Perrone Federica
Published: July 2023

In pseudomyxoma peritonei (PMP), KRAS and GNAS mutations are frequent. We hypothesized that these mutations may contribute to the suppression of antitumor immunity: KRAS may induce GMCSF expression, while GNAS may enhance the expression of cyclic adenosine monophosphate and A2AR signaling. This study aimed to explore possible mechanisms facilitated by KRAS and GNAS mutations for escaping immune surveillance. Additionally, we looked for new potential therapeutic and prognostic targets in this rare disease which is poorly characterized at the molecular level. GM-CSF, A2AR, CD73, CD39, and PD-L1 expression was investigated by immunohistochemistry in 40 PMPs characterized for GNAS and KRAS mutational status. Immune cell populations were studied by immunohistochemistry and nanostring nCounter®. Following the criteria of a prognostic nomogram reported for PMP, we stratified the patients into two different risk groups, with 28 “low-risk” and 12 “high-risk” patients. We observed the expression of GM-CSF (74%); CD39 (37%); CD73 (53%); A2AR (74%); and PD-L1 (16%) which was unrelated to GNAS or KRAS status. The tumor microenvironment showed the presence of CD4+ T cells (86%); CD8+ T cells (27%); CD20+ B (67%); CD15+ cells (86%); and CD163+ M2 macrophages (67%), while CD56+ NK cells were absent. CD163 expression (27%) in PMP tumor cells was associated with poor prognosis. GNAS mutation and A2AR expression were not associated with a specific immune transcriptional signature. However, the expression assay revealed 21 genes associated with prognosis. The “high-risk” patients exhibited worse progression-free survival (HR = 2.3, CI 95%: 1.1–5.1, p = 0.034) and significant downregulation of MET, IL8, PPARG, DTX4, HMGA1, ZIC2, WNT5B, and CCRL2. In conclusion, we documented the presence of immunosuppressive factors such as GM-CSF, A2AR, and PD-L1 in PMP. These factors were not associated with GNAS and KRAS status and could be explored as therapeutic molecular targets. Additionally, a set of potential prognostic biomarkers, including CD163 expression in tumor cells, deserve further investigation.
Effect of 10-Day Treatment with 50 mg Prednisolone Once-Daily on Haemostasis in Healthy Men—A Randomised Placebo-Controlled Trial
Authors: Kamstrup Peter , Rastoder Ema , Hellmann Pernille Høgh , Sivapalan Pradeesh , Larsen Emil List , Vestbo Jørgen , Ulrik Charlotte Suppli , Goetze Jens P. , Knop Filip Krag , Jensen Jens Ulrik Stæhr
Published: July 2023

Synthetic corticosteroids are widely used due to their anti-inflammatory and immunosuppressant effects. Their use has been associated with venous thromboembolism, but it is unknown whether thromboembolism has a causal relationship with corticosteroid treatment. In a randomised, double-blind, placebo-controlled trial in normal to overweight healthy men, the effect of the corticosteroid prednisolone on haemostasis using either 50 mg prednisolone or matching placebo once daily for ten days was investigated. The primary outcome was a change from baseline in the viscoelastic measurement maximal amplitude of clot in kaolin-activated thromboelastography (TEG). Changes from baseline in other TEG measurements, D-dimer, von Willebrand factor (VWF) antigen, and ristocetin cofactor activity (RCo), antithrombin, protein C, prothrombin, fibrinogen, INR, APTT, and platelet count were secondary outcomes. Thirty-four men participated in this study. Compared to placebo, prednisolone treatment did not affect maximal amplitude of clot (difference −0.77 (95% confidence interval (CI) −2.48, 0.94) mm, p = 0.37, missing: n = 2), but it altered VWF antigen (28%, p = 0.0004), VWF:RCo (19%, p = 0.0006), prothrombin (5%, p = 0.05), protein C (31%, p < 0.0001), antithrombin (5%, p = 0.013), and fibrinogen (−15%, p = 0.004). Thus, prednisolone treatment did not alter TEG-assessed maximal amplitude of clot, despite that it affected prothrombotic markers (increased prothrombin, VWF antigen, VWF:RCo, prothrombin, and decreased fibrinogen) and increased antithrombotic markers (protein C and antithrombin).
A Postmortem MRI Study of Cerebrovascular Disease and Iron Content at End-Stage of Fragile X-Associated Tremor/Ataxia Syndrome
Authors: Wang Jun Yi , Sonico Gerard J. , Salcedo-Arellano Maria Jimena , Hagerman Randi J. , Martinez-Cerdeno Veronica
Published: July 2023

Brain changes at the end-stage of fragile X-associated tremor/ataxia syndrome (FXTAS) are largely unknown due to mobility impairment. We conducted a postmortem MRI study of FXTAS to quantify cerebrovascular disease, brain atrophy and iron content, and examined their relationships using principal component analysis (PCA). Intracranial hemorrhage (ICH) was observed in 4/17 FXTAS cases, among which one was confirmed by histologic staining. Compared with seven control brains, FXTAS cases showed higher ratings of T2-hyperintensities (indicating cerebral small vessel disease) in the cerebellum, globus pallidus and frontoparietal white matter, and significant atrophy in the cerebellar white matter, red nucleus and dentate nucleus. PCA of FXTAS cases revealed negative associations of T2-hyperintensity ratings with anatomic volumes and iron content in the white matter, hippocampus and amygdala, that were independent from a highly correlated number of regions with ICH and iron content in subcortical nuclei. Post-hoc analysis confirmed PCA findings and further revealed increased iron content in the white matter, hippocampus and amygdala in FXTAS cases compared to controls, after adjusting for T2-hyperintensity ratings. These findings indicate that both ischemic and hemorrhagic brain damage may occur in FXTAS, with the former being marked by demyelination/iron depletion and atrophy, and the latter by ICH and iron accumulation in basal ganglia.