bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Technology in Burn Disaster Response
Authors: Haller Herbert L. , Sander Frank , Ryan Colleen M. , Almeland Stian Kreken , Kamolz Lars Peter
Published: March 2024

Technological advancements in the Internet of Things (IoT), unmanned aerial vehicles (UAVs), and novel technological tools have transformed disaster management practices from localized approaches to a global framework. These innovations necessitate a unified understanding and application of diverse methodologies at an international level, ensuring they are accessible and operational across different sectors. This integration is crucial not only for technical personnel but also for medical teams, who play a pivotal role in disaster response and management. By fostering a comprehensive grasp of these methods, we can enhance coordination, efficiency, and effectiveness in addressing disasters on a global scale. The authors aimed to provide a comprehensive overview of emerging techniques that are driving shifts in strategic approaches and treatment technologies. Recognized as a domain of continuous research and development, this overview, by necessity, remains an incomplete snapshot of an evolving field. It highlights the dynamic nature of technological and strategic advancements, underscoring the importance of ongoing investigation and innovation to stay abreast of current trends and future directions. The article also highlights the importance of international collaboration beyond societal and national boundaries A single paragraph of about 200 words maximum. For research articles, abstracts should give a pertinent overview of the work. We strongly encourage authors to use the following style of structured abstracts, but without headings: (1) Background: Place the question addressed in a broad context and highlight the purpose of the study; (2) Methods: briefly describe the main methods or treatments applied; (3) Results: summarize the article’s main findings; (4) Conclusions: indicate the main conclusions or interpretations. The abstract should be an objective representation of the article and it must not contain results that are not presented and substantiated in the main text and should not exaggerate the main conclusions.
Agronomic and Economic Evaluation of Tree Species in Agroforestry Systems with Cocoa (Theobroma cacao L.) in Amazonas
Authors: Huaman Haro Nixon , Lopezhaya Mendoza Jerry Bryan , Medina Medina Angel James , Zabaleta Santisteban Jhon Antony , Tineo Flores Daniel , Juarez-Contreras Lily , Goñas Malluri , Oliva-Cruz Manuel
Published: March 2024

Agroforestry systems (AFS) are beneficial ecosystems that increase cocoa productivity by providing shade and controlling pests. Despite deforestation, there is a transition towards more sustainable practices that combine diverse species with cocoa, generating economic and environmental benefits. This study evaluates AFS with cocoa in the Amazon region. Of the 72 farms evaluated, species diversity was observed, highlighting Cordia alliadora and Calycophyllum spruceanum with an im-portance value index (IVI) of 18.58% and 17.66%, respectively. Fruit trees such as Citrus limetta, Cocos nucifera, Mangifera indica, and Persea americana are common. The designed AFSs proved more profitable, generating revenue from the fourth year, while the conventional ones took longer. Indicators such as Net Present Value (NPV) and Internal Rate of Return (IRR) supported the effi-ciency of the designed AFS. Six optimal species were identified with specific distances and planting systems, providing up to 45.83% total shade in flat topography and up to 2405 annual shade hours on a 7° slope. These results highlight the economic and agronomic viability of AFSs designed for regional cocoa production.
Analysis of Cell Immunity for Children Infected with COVID-19 and Those Vaccinated against COVID-19 Using T-SPOT®.COVID
Authors: Oishi Tomohiro , Yasui Yuto , Kato Atsushi , Ogita Satoko , Eitoku Takahiro , Enoki Hideo , Nakano Takashi
Published: March 2024

To elucidate the cellular immune response to coronavirus disease (COVID-19) among children, we assessed cellular immunity in 8 children post-vaccination for COVID-19 and 11 children after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, using the T-SPOT®.COVID assay for both the spike (S) and nucleocapsid (N) proteins. In the vaccinated group, the T-SPOT®.COVID assay for the S protein yielded positive results in all eight children. In contrast, in the post-infection group, the assay for the N protein was positive in 5 of 11 children, with 3 of these 5 children requiring hospital admission, including 2 who needed mechanical ventilation. Therefore, the T-SPOT®.COVID assay is valuable for assessing cellular immunity against COVID-19, and most children infected with COVID-19 may not develop such immunity unless the disease severity is significant.
Protocol for the Nutrition for Brain and Body Health Study: A Randomized Feasibility Trial
Authors: Silver Rachel , Gerber Suzannah , Das Sai Krupa , Greene Savana , dao Maria Carlota , Sunwoo John , Ceglia Lisa , Dix Sadie , Barger Kathryn , Franceschini Maria Angeline , Cohen Ronald , Roberts Susan
Published: March 2024

Older adults with obesity have an increased risk for cognitive decline and subsequent Alzheimer’s disease. Previous research has focused on the impact of individual nutrients and overall dietary patterns to improve cognitive function. The Brain and Body Health (BB-Health) study aims to demonstrate the feasibility of a multicomponent nutritional supplement (MCNS) and weight loss (WL) intervention for individuals with overweight and obesity who are not consuming a healthy diet. BB-Health is a parallel-group randomized placebo-controlled 2x2 factorial pilot trial comparing the MCNS, WL, and MCNS+WL with a Control group. Eligible participants are 55 to 85 years of age with a body mass index 27.0 to 39.9 kg/m2. Major exclusion criteria include type 2 diabetes, moderate or severe cognitive impairment, and self-reported healthy dietary pattern. The BB-Health feasibility trial is registered as NCT05542199 at clinicaltrials.gov. The BB-Health objectives are to report: 1) recruitment and enrollment, including pace and descriptive statistics of the study sample; 2) adherence to the administered interventions; 3) successful data collection and performance of outcome assessments, including evaluation of change in key outcomes over time that are powered for this pilot study; and 4) summary statistics on outcomes for use in planning a subsequent, larger trial. The outcomes of interest are age-sensitive cognitive assessments, cerebral hemodynamics, and related health parameters. All measurements are collected at baseline, 3-, 6-, and 12-month visits. If the BB-Health protocol demonstrates feasibility, the novel MCNS with and without a parallel WL intervention has potential to be administered in a confirmatory randomized trial to evaluate ability to prevent age-related cognitive decline and improve brain health. The BB-Health Feasibility Study could significantly contribute to our understanding of the influence of diet and weight management on cognitive health
Aging Mechanism of Mn-based Prussian Blue Cathode Material by Synchrotron 2D X-ray Fluorescence
Authors: Maisuradze Mariam , Li Min , Carlomagno Ilaria , Gaboardi Mattia , Aquilanti Giuliana , Plaisier Jasper Rikkert , Giorgetti Marco
Published: March 2024

The aging mechanism of 10% and 30% nickel substituted manganese hexacyanoferrate cathode material in aqueous zinc-ion batteries has been explored through the advanced synchrotron-based two-dimensional x-ray fluorescence technique. Thanks to the two-dimension modality, not only the metal concentration dynamics throughout the entire electrodes was followed during the aging process, but their spatial distribution was also revealed, suggesting the route of the material transformation. The dissolution of Mn and Ni, and the penetration of Zn inside the framework, alongside the Mn aggregations outside the hexacyanoferrate framework were detected. Additionally, the possibility of conducting x-ray absorption spectroscopy measurements on the regions of interest made it possible to explore the chemical state of each metal, and furthermore, synchrotron-based powder x-ray diffraction demonstrated the gradual structural modification in 30% Ni-containing sample series, in terms of the different phase formation.
Cibenzoline Succinate Poisoning and Cardiac Arrest Treated with Venoarterial Extracorporeal Membrane Oxygenation after Small Overdose: A Case Report
Authors: Nawa Hiroki , Yoshimura Yuya , Nodagashira Tatsuya
Published: March 2024

Introduction: Atrial fibrillation (AF) is a common cardiac arrhythmia whose prevalence rises with age and is linked to increased morbidity and mortality due to the risk of thromboembolism. Management typically involves anticoagulation and rhythm control, but the treatment of elderly patients with multiple comorbidities requires careful consideration of drug side effects and interactions. Cibenzoline, a Vaughan-Williams class IA antiarrhythmic, is effective against AF but has risks of toxicity, especially in older people and those with renal impairment, due to its renal excretion and prolonged half-life in these populations. Discussion: This paper presents a case of an 80-year-old woman with paroxysmal AF who suffered cardiac arrest due to cibenzoline toxicity despite receiving standard adjusted dosages. The patient's cibenzoline blood concentration was significantly higher than the therapeutic range, leading to cardiotoxicity, which was exacerbated by drug interactions with bisoprolol and edoxaban, both metabolized by the CYP3A4 enzyme. Venoarterial extracorporeal membrane oxygenation (V-A ECMO) and intra-aortic balloon pump (IABP) successfully managed the cardiac arrest. This case emphasizes the unpredictable pharmacokinetics of cibenzoline in elderly patients with renal impairment and the need for vigilant therapeutic drug monitoring to avoid adverse events. Conclusions: Cibenzoline can pose a significant risk of severe toxicity in elderly patients with renal impairment, and drug interactions may potentiate this risk. The paper underscores the importance of careful dose adjustment and monitoring of drug levels in this population. In cases of cibenzoline-induced cardiac arrest, V-A ECMO and IABP are effective treatment modalities. The case study serves as a critical reminder for clinicians to remain vigilant for drug-induced complications and to apply aggressive supportive treatments when necessary.
Mesothelioma Associated Fibroblasts Modulate the Response of Mesothelioma Patient Derived Organoids to Chemotherapy through Interleukin-6.
Authors: Cioce Mario , Gatti Veronica , Napolitano Fabiana , Giorgiano Noemi Maria , Marra Andrea , Portella Giuseppe , Fiorelli Alfonso , Pentimalli Francesca , Fazio Vito Michele
Published: March 2024

Background. Malignant pleural mesothelioma (MPM) is still a rather incurable disease. Many classes of compounds with various mechanisms of action have been tested in vivo and ex-vivo, with rather disappointing results. This is partly due to preclinical studies mostly performed in models that fail to recapitulate MPM complexity and do not retain the intra-tumor heterogeneity, a propelling force for tumor progression. Additionally, we and others have shown that, under stress-induced chemotherapy, profound rearrangements take place in MPM cultures to fuel the emergence of chemoresistant cell subpopulations. Thus, finding clinically actionable modulators of MPM resistance is still a very urgent need.
Methods. Setup and propagation of patient-derived organoid cultures from MPM pleural effusions; flow cytometry-based validation of organoid cultures, isola-tion and propagation of mesothelioma-associated fibroblasts; co-cultures, Lu-minex-based Cytokine array, ELISA assay to quantitate IL-6 in the conditioned media, qRT-PCR to assess mRNA expression of cancer stem cell markers and fibroblast markers.
Results. Organoid cultures were obtained from eight MPM patients by using specific growth media and conditions to propagate pleural effusion-derived cells. We proved that primary MPM specimens and serially passaged (mesothelio-ma-Patient-Derived-Organoids) mPDOs were cytologically similar, with the obtained mPDOs expressing mesothelial markers similarly to the originating specimen. As expected from a clinically relevant model, the size and number of mPDOs were altered, in a patient-specific way, when pharmacologically relevant doses of chemotherapy drugs were added. We derived Mesothelio-ma-Associated-Fibroblasts (MAFs) and the addition of MAFs, to various ratios, altered the response of the mPDOs to pemetrexed + cisplatin, toward a reduced sensitivity to the latter anticancer agents. Additionally, organoid formation and size were altered by MAF-conditioned media, and this correlated with increased expression of cancer stem cell markers. We showed increased levels of IL-6 in the media of the treated cocultures and showed that this latter was derived from the MAFs.
Conclusions. Increased secretion of IL-6 by mesothelioma-associated fibroblasts (MAFs) contributes to the resistance of the MPM to therapy.
Greeting Gesture Classification Using Machine Learning Based on Politeness Perspective in Japan
Authors: Wibowo Angga Wahyu , Kurnianingsih  , Saputra Azhar Aulia , Sato-Shimokawara Eri , Takama Yasufumi , Kubota Naoyuki
Published: March 2024

Understanding traditional culture is important. Various methods are used to achieve better cross-cultural understanding, and certain researchers have studied human behavior. However, behavior does not always represent a culture. Therefore, our study aims to understand Japanese greeting culture by classifying it through machine learning. Following are our study contributions. (1) The first study to analyze cultural differences in greeting gestures based on the politeness level of Japanese people by classifying them. (2) Classify Japanese greeting gestures eshaku, keirei, saikeirei, and waving hand. (3) Analyze the performance results of machine and deep learning. Our study noted that bowing and waving were the behaviors that could symbolize the culture in Japan. In conclusion, first, this is the first study to analyze the eshaku, keirei, saikeirei, and waving hand greeting gestures. Second, this study complements several human activity recognition studies that have been conducted but do not focus on behavior representing a culture. Third, according to our analysis, by using a small dataset, SVM and CNN methods provide better results than k-nearest neighbors (k-NN) with Euclidean distance, k-NN with DTW, logistic regression and LightGBM in classifying greeting gestures eshaku, keirei, saikeirei, and waving hand. In the future, we will investigate other behaviors from different perspectives using another method to understand cultural differences.
Gaze-Data-Based Probability Inference for Menu Item Position Effect on Information Search
Authors: Matsushita Yutaka
Published: March 2024

This study examines the effect of menu items placed around a slideshow at the center of a webpage on an information search. Specifically, the study analyzes eye movements of users whose search time is long or short on a mixed-type landing page and considers the cause in relation to “directed search” (which triggers a certain type of mental workload). To this end, a Bayesian network model is developed to elucidate the relation between eye movement measures and search time. This model allows the implementation degree of directed search to be gauged from the levels of the measures that characterize a long or short search time. The model incorporates probabilistic dependencies and interactions among eye movement measures, and hence it enables the association of various combinations of these measure levels with different browsing patterns, helping judge whether directed search is implemented or not. When viewers move their eyes in the direction opposite (identical) to the side on which the target information is located, the search time increases (decreases); this movement is a result of the menu items around the slideshow capturing viewers’ attention. However, viewers’ browsing patterns are not related to the initial eye movement directions, which may be classified into either a series of orderly scans (directed search) to reach the target or long-distance eye movements derived from the desire to promptly reach the target (undirected search). These findings suggest that the menu items of a website should not be basically placed around a slideshow, except in cases where they are intentionally placed in only one direction (e.g., left, right, or below).
Estimation of Object Handover Position Using Human-Robot Proxemics and Unsupervised Pattern Recognition
Authors: Rahmah Syadza Atika , Kubota Naoyuki
Published: March 2024

The increasing elderly population presents significant challenges in terms of the meeting of their daily care needs. Cognitive decline and reduced arm reflexes following balance loss impede the elderly’s execution of activities of daily living. To address these challenges, robots have emerged as valuable assistants for elderly individuals in their daily activities, including object manipulation, and have the potential to significantly improve the quality of life for the aging population. However, no research has been undertaken to enhance the selection of object handover locations in human-robot interactions by merging topology mapping with both parties’ range of motion, based on personal space. Based on the idea of personal space within human-robot proxemics, this research presents an alternative approach that makes use of topological mapping while taking into account the range of motion of both humans and robots. This research aims to minimize the expenses related to human-robot proximity and to determine the best locations for item handovers in order to discover which locations are optimal. In order to improve object handover locations, this work is a groundbreaking attempt to combine growing neural gas and human proxemics inside a robotic framework. Furthermore, it implies the creation of robot behaviors that resemble human proximity by estimating personal distances and incorporating rule-based requirements for item handover locations by taking into account the mobility ranges of both humans and robots. The simulation findings reported in this work show the ability of the suggested methodology and offer interesting information and prospects for further developments in the area of object handovers by robots.
Frank Sibley'de Estetik Kavramlar ve Beğeni Duyusu Üzerine Bir İnceleme
Authors: POLAT Alper Elvan
Published: March 2024

Estetik, 18. yüzyılda ilk defa Baumgarten tarafından felsefi bir terim olarak ele alındıktan sonra estetik alanının temel problemlerinden biri de güzellik kavramı ve beğeni duyusunun neliğini belirlemek olarak karşımıza çıkmıştır. Bu doğrultuda bu problemin kökleri Platon'a kadar dayandırılabilirken 20. yüzyıl, sanat akımlarının ve sanatsal faaliyetlerin çeşitlendiği bir dönem olması yönüyle estetik alanındaki çalışmalar açısından pek çok farklı fikrin de öne çıktığı bir dönem olmuştur. Bu yüzyılda Frank Noel Sibley, “Estetik Kavramlar (Aesthetic Concepts)” adı altında birleştirdiği çalışmalarıyla felsefe çevrelerinde yeni bir tartışma başlatmış ve estetiğin sınırlarının belirlenmesi için estetik kavramlar ile estetik-dışı kavramlar ayrımı yapmış; bu ayrımın temeline de her insanda doğuştan bir potansiyel olarak bulunduğunu iddia ettiği beğeni duyusu kavramını yerleştirmiştir. Bu çalışmada Sibley'in adı geçen eseri temele alınarak estetik tartışmalarında sıkça atıfta bulunulan ve Sibley tarafından özgün bir biçimde ele alınan “estetik kavramlar” ve “beğeni duyusu” kavramları incelenerek serimlenmeye çalışılmıştır.
Els reptes per a l’emancipació dels joves a les comarques de Lleida
Authors: Enciso Rodríguez Joan Pere , Allepuz i Capdevila Rafael , Mateos José Tomás , Pardes Fuses Isarn , Pardes Fuses Otger
Published: March 2024

Aquest estudi pretén comprendre la situació en què es troben les persones joves i les dificultats i limitacions que afronten a l’hora de construir-se un projecte de vida. També vol detectar possibles diferències significatives en el procés d’emancipació entre una persona jove d’una zona rural i una d’una zona urbana. El marc territorial utilitzat són les diferents comarques circumscrites a la província de Lleida. El text es divideix en dos grans blocs: el primer, més conceptual i de contextualització, i el segon, en què es descriuen els diferents reptes per emancipar-se que tenen les persones joves de les comarques de Lleida.
Pelatihan Digital Marketing untuk Strategi Branding bagi Koperasi, UKM, dan Kelompok Strategis
Authors: Istiqomah Nur Hidayatul , Zakariya A. Fahmi , Rustyawati Dian
Published: March 2024

Efek dari pandemi dan aturan pembatasan aktivitas masyarakat telah mengakibatkan penurunan omset penjualan. Oleh karena itu, Koperasi, UKM, dan Kelompok Strategis perlu menjadi lebih kreatif dan inovatif dalam menjalankan aktivitas pemasaran. Pemasaran digital atau pemasaran online adalah solusi yang tepat untuk mengatasi masalah ini. Namun, masih ada banyak pelaku Koperasi, UKM, dan Kelompok Strategis yang belum memahami pemasaran digital. Oleh karena itu, diperlukan pelatihan dan bantuan pemasaran digital agar mereka dapat bersaing dan inovatif dalam meningkatkan omset penjualan di era pandemi. Tujuan dari pelatihan dan bantuan pemasaran digital ini adalah memberikan pengetahuan dan keterampilan kepada pelaku Koperasi, UKM, dan Kelompok Strategis untuk meningkatkan penjualan melalui pemasaran digital. Metode Pelatihan Digital Marketing untuk Strategi Branding bagi Koperasi, UKM, dan Kelompok Strategis adalah dengan melakukan tahap persiapan dan tahap pelaksanaan. Hasil Pelatihan Digital Marketing untuk Strategi Branding bagi Koperasi, UKM, dan Kelompok Strategis menunukkan bahwaMelalui social entrepreneurship, masyarakat dapat lebih terlibat dalam mencari solusi atas masalah sosial dan lingkungan di sekitarnya.
Changes Da’wah of Kyai Hasyim in the Naqsabandiyah Order in Jember, 1982-2013
Authors: Yaqin A. Ainul , Fawaidi Badrun , Aliyar M Satheem
Published: March 2024

This article examines the Naqsabandiyah Mujaddadiyah Khalidiyah Order in Jember during the leadership period of KH. Abdul Wahid Hasyim Nawawi in 1982-2013. The historical approach was used in this study with a descriptive qualitative model which was analyzed through Anthony Giddens' structuration theory regarding the influence of the kyai obtained due to the structure of the surrounding community. The author considers this study important to write because the Naqsabandiyah Mujaddadiyah Khalidiyah (TNMK) Order in Jember has not been well documented by the community. Thus, TNMK is basically seen as exclusive by the community which then raises negative prejudice from the community. The results in this study the role of Kyai Hasyim through: routine studies, strengthening sharia issues, increasing patience, building emotional relationships and living tolerance can have an impact on social change in the Jember community, both in educational institutions and social life. Among the several roles played by Kyai Hasyim in dealing with a multicultural society, it is very possible if the structure concept used in the Naqsabandiyah Mujaddadiyah Khalidiyah Tarekat uses the "contemporary Sufism" model, so that it is easier for people to understand the tarekat and become a new paradigm in the development of the tarekat in the next leadership.
Penafsiran Paradigma Wahdah Al-Wujud Dalam Pemikiran Islam: Studi Komparasi Gagasan Kesatuan Wujud Ibrahim Al-Kurani Dan Mulla Sadra
Authors: Rahman Fadhlu , Muzammil Shofiyullah
Published: March 2024

Wahdah al-Wujud as one of the important concepts of Islamic studies has different ontological interpretations between philosophers and Islamic theologians and Sufis. These different interpretations result in ontologically significant differences in understanding implications. This study seeks to answer the problem of differences in the interpretation of the concept of wahdah al-wujūd from two major figures who indirectly have the same spirit, namely to harmonize various approaches and scholarship in Islam but have different positions and tendencies in interpreting the concept of wahdah based on each socio-cultural background. This research was conducted using the onto-epistemological analysis method which is part of the branch of philosophy. This research concludes that the ontological status constructed by al-Kurani has implications for theological wahdah al-wujūd which explicitly avoids the equality of creatures with God (tanzih and tasbih), while sadra still sees one entity but in different gradations. In addition, al-Kurani still assumes absolute nothingness, while Sadra assumes relative nothingness as the basis for the creation of a reality other than God. Finally, al-Kurani tends to adopt the theological doctrine of al-Kasb as the basis for the relevance of the interpretation of wahdah al-Wujud, while Sadra adheres to the principle of philosophical non-contradiction
To Die Before Death: Intersubjectivity of Bay‘at Ritual in Tarekat Naqsyabandiyah Kadirun Yahya (TNKY)
Authors: Sandika Firman Aulia , Adenan Adenan
Published: March 2024

Bay‘at ritual is one of the important activities in the tarekat. Bay‘at as the initial process of a prospective student, confirms a steadfast commitment to the doctrines and rituals taught in the tarekat. In practice, each tarekat has a different method and technique. To understand bay‘at ritual practiced at the Tarekat Naqsyabandiyah Kadirun Yahya (TNKY), a research question was asked about the process and experiences of prospective students who participated in bay‘at ritual. To answer the research questions used, qualitative methods with a phenomenological approach. The data source comes from the intersubjectivity of researchers and is equipped with other supporting data. Observation, interviews, and documentation were carried out in data collection, and data analysis was carried out by simplification, grouping, and interpretation stages. The findings of this study explain that before the initiation process is carried out, three orientations will be carried out to provide knowledge and ensure the readiness of prospective students to join TNKY. The process of bay‘at is carried out with the stages of bathing, repentance, praying sunnah, sleeping on its side like a corpse, and being covered with a shroud. The intersubjectivity of physical experience following bay‘at feels cold, hot, sore, sleepless, and uncomfortable. The inner experience gives rise to feelings of being tormented, constrained, afraid, and others. Still, the process of “torture” that is going through raises the awareness that only Allah is the place to ask for help and always strive to be connected to Him through remembrance.
Between Sufism and Marxism: Social Religious Movements in Twentieth Century Minangkabau
Authors: Hasan In'amul , Nurwahidin Nurwahidin
Published: March 2024

The Sufi movement in Minangkabau in the 20th century was influenced by Marxism. In some Muslim scholars' views, Marxism could not possibly be in line with Islam. On the ground, Islam and Marxism were able to act in dialectic as a weapon against colonialism that hit the entire Muslim society at the time. In Minangkabau, which has an Islamic view of life, the ideology of Marxism spread rapidly and captured the attention of the public, including the Sufis. To analyze this study uses the theory of social action by Max Weber, which is divided into four types, traditional action, affective action, instrumental rationality, and value rationality. Based on the traditional type, the Sufi tried to follow their teachers, as well as the tradition of the Padri, who went against colonialism. Through affective actions, the Sufis demonstrated a strong emotional bond to the system that exists in the Sufi tradition. Using instrumental rationality, they were consciously able to carry out the resistance rationally after seeing the available resources. In terms of rationality of value, the Sufis want to receive the reward for their jihad (mujahada), as had been done by the other Sufis before them
Women, Piety, and Religious Behavior (Case Study of the Muslimah Ummahat Sholehah Community in Sukodono Tahunan Jepara)
Authors: Saefudin Ahmad , Arif Mahmud , Karwadi Karwadi , Rahmawati Affiyah , Paduka Wanamean , Andriyani Santi
Published: March 2024

This study aims to describe the manifestation of piety constructed by women who are members of the Muslimah Ummahat Sholihah Community. Also, to analyze the level of their religious behavior. This research is a qualitative descriptive study that emphasizes field research. Researchers used observation techniques, interviews, questionnaires, and documentation to collect data. It turns out that the manifestation of women's piety is manifested by being obedient to the commands of Allah and His Messenger through the intermediary of teachers, covering their genitals and wearing the hijab, obeying their husbands, balancing ritual worship with social activities, and participating in religious activities. Meanwhile, the level of religious behavior of members of the Muslimah Ummahat Sholihah Community based on the results of the distribution of the questionnaire is categorized as high. Thus, the symbol of piety that they carry has absolutely nothing to do with conservatism, even radicalism, as some observers have alleged.
Wacana Dinamis Nahdlatul Ulama: Analisis Kritis terhadap Perubahan Sosial
Authors: Haeba Ilham Dwitama , Thoha Anis Malik , Ahim Rasinah
Published: March 2024

This research presents critical study of Nahdlatul Ulama’s dynamic discourse on social change. The background of this study is rooted in the significant role of NU in the history of Indonesia, particularly in the realm of cultural and religious ideologies. The research methodology employed encompasses a combination of qualitative approaches and document analysis to attain a comprehensive and profound comprehension, to understand how the NU tradition is integrated into moderate thinking and the extent to which the transformation of such thinking can act as a catalyst for societal progress. The theoretical framework of this research encompasses a profound understanding of the traditional values of NU, the concept of moderation as the cornerstone of thinking, and how thinking evolves in the face of contemporary challenges. The results of the analysis indicate that NU traditions not only persist in everyday life but are also effectively assimilated into the modern context. Moderation, as a pivotal aspect of NU thought, emerges as a crucial component in promoting interreligious dialogue and contributing to political stability. The transformation of NU's thinking is evident in its response to advancements in technology and science. Although NU thinking encounters challenges, particularly in preserving cultural heritage, this study underscores the opportunities for the development of NU thinking in the future. The conclusions of this study offer a critical evaluation of NU's impact on societal change and emphasize the significance of comprehending and permeating traditional values while remaining relevant in the face of evolving times. The implications of this research hold valuable insights for academics, practitioners, and policymakers in supporting the positive development of a society founded on the moderate values of NU.
Effect of ZnO NPs on Ovarian Histological Structure and Function in Adult Female Rats
Authors: Luaibi Noori M. , Lazim Faisal G. , Muhammed Haidar J.
Published: March 2024

تعد تقنية النانو واحدة من أهم التقنيات المستخدمة على نطاق واسع في العديد من المجالات من خلال تغيير خصائص المواد الفيزيائية والكيميائية لتكوين مواد جديدة تسمى الجسيمات النانوية لجعلها أكثر فعالية. تعتبرجسيمات أوكسيد الزنك النانوية هي واحدة من هذه الجزيئات التي تستخدم في تطبيقات متعددة ، خاصة في مستحضرات التجميل ومنتجات الوقاية من اشعة الشمس. ولهذا فإن استخدام هذه الجسيمات بكميات كبيرة يجعلها بتماس دائم مع الجسم والتي من الممكن أن تدخل الدورة الدموية بطرق مختلفة. كان الهدف من هذه الدراسة هو التحري عن تأثير جسيمات أوكسيد الزنك النانوي على التركيب النسجي والوظيفي للمبايض وكذلك تقييم مستوى هرمونات الغدد التناسلية (FSH و LH). ولاجل ذلك تم استخدام 54 من إناث الجرذان البالغة وقسمت بشكل عشوائي إلى ثلاث مجاميع رئيسية وفقًا الى فترات التجريع (1 ، 2 ، 4) أسابيع ، بعدها قسمت كل مجموعة رئيسية إلى ثلاث مجاميع فرعية ، كل مجموعة منها تتكون من 6 جرذان ، احدى هذه المجاميع تم استخدامها كمجموعة سيطرة وحقنت بـ  1 مل  من الماء المقطر ، بينما المجموعتين الأخرى استخدمت كمجاميع معالجة وحقنت بـ  1 مل  من محلول اوكسيد الزنك النانوي (ZnO NPs) بتركيزين مختلفين منخفض وعالي (50 و 200) مغم / كغم على التوالي ، بمعدل ثلاث جرعات في الأسبوع عن طريق الحقن داخل الصفاق. أظهرت النتائج تغيرات نسجية مختلفة في مقاطع أنسجة المبايض لدى الجرذان المجرعة بتراكيز وفترات زمنية مختلفة ، وكذلك أظهرت النتائج ايضا" انخفاض معنوي (p≤ 0.01)  في مستويات هرمون الاستروجين والبروجسترون و LH و FSH ، لدى الحيوانات المعالجة بتراكيز وفترات زمنية مختلفة. وقد تم الأستنتاج بأن لجزيئات دقائق الزنك النانوية القدرة على إتلاف أنسجة المبيض ، وتعطيل وظائفه الخلوية مما أدى الى خلل في مستويات الهرمونات التناسلية (P و E2 و LH و FSH).
Synthesis, characterization, industrial and biological studies of azo dye ligand and their some metallic ions
Authors: Hussein Abaas Obaid , Abbas Rana Abdulilah , Al-Zinkee Jinan M. M. , Jarad AmerJ.
Published: March 2024

حضر4-((2-هيدروكسي-3،5- ثنائي نيترو) دايازنيل) 1،5-ثنائي مثيل- 2-فنيل-1بايرازول-3-((2H-اون من مفاعلة ملح الدايازونيوم للمركب 4-امينو انتي بايرين مع 2،4- ثنائي نيتروفينول. تم تشخيص الليكاند بوساطة طيف الأشعة فوق البنفسجية- المرئية والأشعة تحت الحمراء وطيف الرنين النووي المغناطيسي للبروتون والكاربون وطيف الكتلة ، فضلا عن قياس التحليل الدقيق للعناصر(C.H.N.O) . حضرت معقدات الكوبلت (II) والنيكل (II)والنحاس(II) والخارصين(II) وشخصت بوساطة تقنية الامتصاص الذري اللهبي واطياف الأشعة فوق البنفسجية- المرئية والأشعة تحت الحمراء والتحليل الدقيق للعناصر(C.H.N.O)، فضلا عن قياسات التوصيلية المولارية والحساسية المغناطيسية. درست تراكيب المعقدات باستخدام طريقتي النسب المولية والمتغيرات المستمرة، وخضعت محاليل هذه المعقدات لقانون لامبرت – بير ضمن مدى التراكيز  - 3×10-4 M ) 10×1)، اشارة النتائج التحليلية ان نسبة فلز: ليكاند هي (1:2). ومن خلال النتائج التحليلية تم اقتراح الشكل ثماني السطوح للمركبات المحضرة ، كما تم اختبار المركبات المحضرة للدراسات الصناعية والبايولوجية.
Amoxicillin and Favipiravir Bio-Degradation by Aspergillus Flavus Fungus
Authors: Al-Shammari Rana Hadi Hameed , Ali Shaimaa Satae M. , Al-Mamoori Ayad M.J.
Published: March 2024

الهدف من هذه الدراسة هو عزل وتوصيف الفطريات القادرة على التحليل الحيوي للأموكسيسيلين و  الفافيرافير وكذلك تحديد خصائصها ومسار التحلل. تم عزل الفطر الاسبرجلس من عينات المياه العادمة الملوثة باستخدام أجار البطاطا ووسط  الجابك.   تم دراسة المعالجة الحيوية في الوسط السابق باستخدام  Amoxicillin و Favipiravir  كمصدر وحيد للكربون. تم التحري عن المواد الناتجة من التحلل بواسطة كروماتوجرافيا سائلة عالية الأداء (HPLC) واستخدمت لاستنتاج مسار تحلل المضادات الحيوية بواسطة الفطر اسبرجلس. تم فحص الخيوط الفطرية عن طريق المجهر الإلكتروني  الماسح قبل وبعد 7 أيام من العلاج لاكتشاف تراكم المضادات الحيوية والتغيرات الشكلية في الخيوط الفطرية. اذ يمكن للفطريات اعتماد المضادات الحيوية كمصدر وحيد للكربون.اذ لوحظ اقصى قدر من التحلل الحيوي هو  91٪  عند اقل تركيز من اموكسيللين. وفقًا لنتائج HPLC  كان زمن الاحتجاز للأموكسيسيلين القياسي 8.12 دقيقة بعد التحلل الحيوي إلى مركبات أخرى مع زمن احتجاز 3.75 دقيقة بنسبة 73.25٪ ، وفي 5.81 دقيقة بنسبة 16.44٪ وفي 8.5 دقيقة بنسبة 8.59 ، وفقًا لمعيار احتباس فافيبيرافير. ظهر الوقت في 3.97 دقيقة ولكن بعد العلاج ظهرت مادتان في 2.20 دقيقة. حسب المنطقة: 62.58٪ وفي 6.16 دقيقة. حسب المنطقة: 20.15٪. لاوحظ تراكم جزيئات  Favipiravir على الخيوط الفطرية    A. flavus . تعطي هذه النتائج رؤى في تحسين طريقة المعالجة الحيوية لإزالة المضادات الحيوية من مياه الصرف الصحي قبل تصريفها في الأنهار .
Parallel lightweight Block Cipher algorithm for Multicore CPUs
Authors: Hamiza Hawraa  J. , Fanfakh Ahmed
Published: March 2024

أصبحت حماية البيانات واحدة من أهم القضايا على الرغم من التقدم الكبير في الاتصالات والتكنولوجيا. لكي ترسل التكنولوجيا المستندة إلى الويب البيانات بسرعة وأمان ، يجب تشفير البيانات. التشفير هو عملية تحويل النص العادي إلى نص مشفر ، لا يستطيع الأشرار قراءته أو تغييره. تتطلب كل من إجراءات تحليل التشفير وفك التشفير قدرًا كبيرًا من الوقت من أجل الحفاظ على المستوى المطلوب من الأمان. ومع ذلك ، طور عدد من الباحثين نهج التشفير بالتوازي من أجل تقليل مقدار الوقت اللازم لإنهاء إجراءات التشفير وفك التشفير. أنتج التحقيق في هذه القضية عددًا من الحلول القابلة للتطبيق. تمكن الباحثون من تحقيق مستويات أداء محسّنة في تقنية التشفير باستخدام التوازي لزيادة الإنتاجية وتعزيز كفاءة طرق التشفير. لتحقيق أداء عالٍ ، تم تقديم خوارزميات تشفير البقعة خفيفة الوزن وتنفيذها على منصات وحدة المعالجة المركزية مع تحسينات مختلفة. وبالتالي ، في هذا العمل ، تم اقتراح مخطط تشفير خفيف الوزن يستخدم جولة واحدة فقط من تقنية تشفير الكتلة التي يتم تطبيقها بالتوازي على معالج متعدد النواة. تستخدم خوارزمية تشفير الرسائل المقترحة كتلتين فرعيتين من 128 بت من الرسائل العادية ومربع الاستبدال و splitmix64 PRNG لتشفير الرسالة العادية والحصول على كتلتين فرعيتين مشفرتين ، مما يجعلها تقنية سريعة لتشفير وفك تشفير كتل الرسائل. بالمقارنة مع الطريقة الحالية. وفقًا لنتائج الأداء ، فإنه قادر على الوصول إلى إنتاجية عالية للبيانات مقارنة ببعض الأساليب خفيفة الوزن الموجودة بالفعل ، مع معدل نقل أعلى من 25 كيكابت في الثانية على وحدة المعالجة المركزية Intel Core i7. تتفوق طريقة التشفير المقترحة على طريقة البقع المتوازية بمعدل 14.10 مرة أسرع عند تنفيذها على وحدة معالجة مركزية متعددة النواة. متوسط التسريع مقارنة بالنسخة التسلسلية للخوارزمية المقترحة والتنفيذ المتوازي لها هو 4.70. أيضًا ، توفر طريقة التشفير المقترحة قدرًا كبيرًا من العشوائية وتجتاز الاختبارات الإحصائية لـ PractRand. وبالتالي ، فإن الطريقة المقترحة هي منافس قوي للتنفيذ عالي الأمان على المعالجات متعددة النواة.
Research on the Effects of an Electrode Drill Bit during the Rock Drilling Process by High-Voltage Electric Pulse
Authors: Duan Longchen , Liu Xianao , Li Changping , Kang Jifeng , Zhang Di , Yuan Zhong
Published: March 2024

High-voltage electric pulse rock-breaking (HVEPB) has proved to be a novel and inexpensive method of breaking rock regardless of rock composition, but the design of the electrode drill bit lacks a theoretical basis. In this paper, we first establish a plasma channel model for electric breakdown and a numerical rock-breaking model for HVEPB, which can simulate the rock electrical breakdown plasma channel and the effect of different electrode drill bits on HVEPB. Second, we analyze the effects of different electrode arrangement structures and high-voltage electrode angles on plasma channels and the effects of internal cracks and rock-breaking processes through numerical simulation. Finally, we describe HVEPB experiments conducted using electrode drill bits with different electrode arrangement structures and high-voltage electrode angles, and with the boreholes reconstructed in three dimensions to analyze the effects of different electrode arrangement structures and high-voltage electrode angles on HVEPB drilling. The results show that the effects of the electrode drill bits on HVEPB are reflected mainly in the difference between the plasma channel and shock wave. Different electrode arrangement structures and high-voltage electrode angles result in different electric fields and energy utilization efficiencies within the rock, resulting in different shock waves and differences in the depth, shapes, and penetration of the plasma channels. The simulations and experimental studies in this paper can guide and optimize the design of the discharge tool to upgrade the drilling efficiency of HVEPB.
Seventh Report of the New Mexico Bird Records Committee
Authors: Williams Sartor O. , Baumann Matthew J.
Published: March 2024

During the period November 2010 through December 2022, the New Mexico Bird Records Committee reached final decisions on 1188 records involving 154 species plus three species groups, accepting 1051 records. Twenty species were added to the New Mexico state list, including one new to North America north of Mexico, the Rufous-necked Wood-Rail (Aramides axillaris), bringing the state list of species confirmed by specimen, photograph, or audio recording to 552 through 31 December 2022.
Metabolic rewiring underpins human trophoblast induction
Authors: Żylicz Jan , Nerum Karlien van , Wenzel Anne , Muntadas Lidia Argemi , Kafkia Eleni , Lavro Viktoria , Roelofsen Annina , Drews Anta , Arnal Sandra Bages , Zhao Cheng , Sanzo Simone di , Volker-Albert Moritz , Petropoulos Sophie , Moritz Thomas
Published: March 2024

Development is driven by a sequence of molecularly interconnected transcriptional, epigenetic, and metabolic changes. Specific metabolites, like α-ketoglutarate (αKG), function as signalling molecules affecting the activity of chromatin modifying enzymes. It remains unclear, how such non-canonical function of metabolism coordinates specific cell-state changes especially in early development. Here we uncover that when naive human embryonic stem cells (nESC) are induced towards human trophoblast stem cells (hiTSC) a significant metabolic rewiring occurs, characterised by the accumulation of αKG. In vivo transcriptomic data further confirmed that metabolic rewiring likely takes place in the nascent trophectoderm (TE). We show that the intracellular αKG level is an important regulator of TE fate acquisition. Indeed, a dimethyl-αKG (dm-αKG) treatment of nESC increases their competence towards TE-like cells during hiTSC induction. Moreover, dm-αKG also increased the robustness of blastoid polarisation, marking the first step of TE induction. Surprisingly, dm-αKG treatment does not affect global histone methylation levels in nESC, but rather leads to decreased H3K27ac and weakening of the pluripotency network. Further functional assays confirmed that both reduced histone acetyltransferase activity and increased αKG level promote nESC competence towards TE-lineage but not extraembryonic mesoderm. We propose that an increased αKG level regulates pluripotency through deacetylation, thus creating a positive feedback loop promoting the induction of TE fate.
Morphology-based Machine-Learning for Predicting Lymph Node Status in Oral Tongue Squamous Cell Carcinoma
Authors: Zhu Yunjing , Ren Jiliang , Song Yang , Tao Xiaofeng , Yuan Ying
Published: March 2024

Purpose
To develop machine-learning models based on morphological features extracted from preoperative magnetic resonance imaging (MRI) to predict lymph node status in oral tongue squamous cell carcinoma (OTSCC).
Method
This study retrospectively enrolled 90 OTSCC patients, of whom 45 and 13 patients, respectively, had confirmed lymph node metastasis (LNM) and extranodal extension (ENE). Fourteen morphological features and two customized metrics were derived from T2-weighted (T2W) images. Tumor maximum diameter and MRI-derived depth of invasion (DOI) were measured on contrast-enhanced T1-weighted (ceT1W) images. Information gain algorithm was applied to select the top five attributes. Models were created using six machine-learning methods, including neural network (NN), random forest (RF), logistic regression (LR), support vector machine (SVM), naïve bayes (NB), and AdaBoost. An internal stratified 10-fold cross-validation was performed to assess their performance.
Results
For predicting LNM, the NN classifier, which included Situation, Elongation, Top Bottom Area, Least Axis Length, and Minor Axis Length, yielded the best model, with an AUC of 0.746 and accuracy of 72.2%. The performance of the NN model was slightly superior to that of MRI-derived DOI (0.746 vs. 0.655), although the difference was not significant (P = 0.122). For predicting ENE, the SVM classifier, which included situation, Elongation, Top Bottom Area, Least Axis Length, and Minor Axis Length, performed the best, with an AUC of 0.750 and accuracy of 85.6%.
Conclusions
Machine-learning models using MRI morphological features have potential in preoperative evaluation of cervical lymph node status in OTSCC.
Multi-Phenotyping and Genotyping of Spanish Groundnuts from Diverse Crosses to Identify Stable donors for Fresh Seed Dormancy and Selection of High-Yielding Stable Genotypes in the genetic background of dormant lines-BLUP, YREM, and AMMI model based stability
Authors: Rani Kirti , K Gangadhara , BC Ajay , Kona Praveen , Kumar Narendra , Bera Sandip
Published: March 2024

Breeding high yielding groundnut cultivars with 2–3 weeks of fresh seed dormancy, particularly in Spanish-type cultivars, enhances the sustainability of agriculture in groundnuts. In this context, we conducted a comprehensive phenotypic and genotypic evaluation of advanced breeding lines developed in the genetic background of Spanish types. By employing multi-phenotyping and marker data, we identified PBS 15044, 16004, 16013, 16015, 16016, 16017, 16020, 16021, 16026, 16031, 16035, 16037, 16038, 16039, 16041, and 16042 with 2–3 weeks dormancy (> 90%). AMMI1 biplots, ASI, BLUP and WAASB estimates identified the stable fresh dormant genotypes with one more superior economic trait. PBS 16021, 15044, 16038, and 16039 identified with high HPW were also reported having high intensity of dormancy (> 90% for up to 3 weeks); PBS 15044, 16016, PBS 16038 and PBS 16039 with high HKW also reported with up to 3 weeks fresh seed dormancy; and PBS 16013, 16031, and 16038 with up to 3 weeks fresh seed dormancy had high SP. They can be used to develop lines with the desired level of dormancy, and high yields, by designing appropriate breeding strategies.
Understanding the Diversity of Human Gut Microbes in Indigenous Populations Across the World
Authors: Mollick Sahid Afrid , Maji Suvendu
Published: March 2024

The microbial population of the human gut plays an important role in maintaining host homeostasis. The human digestive Microbiota is a diverse domain that lies behind the colorful fabric of indigenous civilizations. High-throughput 16S targeted amplicon sequencing has delineated the structural configuration of the gut metagenome in world indigenous populations. The gut microbiota of the indigenous populations holds a wide diversity due to their strategic geopolitical habitat, environment dependent lifestyles, adaptive strategies and unique cultural practices. People's dietary choices and preferences, as well as cultural norms and regulations of the society, shape the overall composition of their gut microbiota. . In this study we employed 16S sequencing data of the gut microbiota samples from 464 individuals of 21 indigenous populations with different socio-demographic background across diverse geographic locations. The study overall display the significant role of geography over the diet and lifestyle of a community. Moreover hunter-gatherers and pastoralists of different geographical location have unique gut microbial composition, suggesting the influence of environment over their subsistence economy. Specific bacterial groups like Prevotellaand Bacteroides are key players in shaping these gut landscapes, identifying the complex interplay between man-environment relationships.
Financial Inclusion among Indian States:An Analysis through the Financial Inclusion Index (FII)
Authors: Kasturi Alivelu , Annemalla Ramesh
Published: March 2024

This study aims to estimate the level of financial inclusion (FI) among the states of India for a two decades. To know this study constructed a FI index then a two-stage PCA method was used. Secondary data from the Reserve Bank of India (RBI) and Economic and Political Weekly Research Foundation (EPWRF) reports for 2000–2020 is used. The study has determined an overall FI index using the dimensions of availability, Penetration, and Usage. The results show that Goa, Kerala and Tamil Nadu states topped with high FI, while Mizoram, Nagaland, Manipur, and Meghalaya states ranked with low FI in the entire study period. The close coordination between the RBI, Government, NABARD, and the other implementing agencies will result in the achievement of financial inclusion in a short period.
JEL Classification: G21, G22, G28, C43, B26