bluuebunny/crossref_metadata_2025 huggingface dataset:
Algorithm to forecast entrepreneurship population using Fuzzy Time Series
Authors: Argote Milenka Linneth , Parra Leon Darío
Published: October 2022

The development of this article required researchers to run several simulations with an FTS model, to project the entrepreneurial population under different values of the parameter C belonging to the bell-shaped membership function. Taking "entrepreneurial population growth" as a linguistic variable, researchers analyzed the potential of the model to adjust to the dynamics of the phenomenon under study, and used an FTS time-invariant. Algorithms were developed in R to run the different stages of the projection model; and experiments using rates as a measure to eliminate sample bias were carried out. The sensitivity of the model to different values of C ranging from 0 to 1 was also analyzed. The results show that the model is robust to project the historical data of the entrepreneurial population in Colombia. The sample data are unstable, however, when projecting the rates, the results are consistent. The lowest error is 0.04142 for C=0.01. Researchers also performed a comparative analysis to evaluate the potential of the FTS-R method to project the entrepreneurial population.
The Experiences and Needs of Early Childhood Special Education Teachers on the Management of Hospital Dispatch Classes for Young Children with Severe and Multiple Disabilities
Authors:   Korean Journal Of Early Childhood Special Education, Lee Eunjeong , Noh Jina
Published: October 2022

The purpose of this study is to investigate the experiences and needs of early childhood special education teachers who have managed hospital dispatch classes for children with severe and multiple disabilities. For this purpose, individual interviews were conducted with 5 early childhood special education teachers who had experience working in a hospital dispatch class in city D. Data collected through individual interviews were analyzed into 3 themes, 7 subcategories, 20 semantic units through qualitative content analysis. The main findings were as follows. First, the participants felt confused when they encountered the unique form of a hospital dispatch class, but they communicated with each other and overcame difficulties, and were operating the class taking advantage of the characteristics of each hospital. Second, the participants felt difficulties in teaching children with severe and multiple disability, in terms of the characteristics of students, managing various curriculum due to students of a wide age range, communication with parents, and emotional aspects such as alienation and loneliness. Third, the participants needed professional manpower supply, guidance and training related to children with severe and multiple disabilities. Based on these results, it was discussed how to support early childhood special education teachers who run hospital-dispatched classes for children with severe and multiple disabilities.
Research Analysis Based on Quality Indicators of 2011-2021 Studies of Positive Behavior Supports for Young Children with Disabilities and at Risk
Authors:   Korean Journal Of Early Childhood Special Education, Kim Taeyoung
Published: October 2022

The purpose of this study was to review the current research studies’ quality indicators that implemented positive behavior support intervention for young children with a disability and at risk. A total of 42 studies including 28 single subject studies, 9 quasi-experimental studies, and 5 mixed studies from 2011 to 2021 were found as appropriately met the inclusive criteria. Single subject studies were reviewed based on quality indicators that were suggested by Horner et al.(2005) while quasi-experimental studies were reviewed based on them by Gersten et al.(2005). The findings of research synthesis presented that most of SSD studies met the criteria of the quality indicators except result of generalization. Quasi-experimental studies included information of participants, research settings, and intervention implementation while several studies did not include explanation of comparative group, and result measurement. Therefore, implications for future research are discussed to address generalization results for SSD studies and several important quality indicators for quasi-experimental studies in order to provide evidence-based research.
Market efficiency and global issues: A case of Indonesia
Authors: Swandari Budiarso Novi , Pontoh Winston
Published: October 2022

The efficient market hypothesis assumes that the stock prices fully reflect all relevant information. Under the weak form, the future prices are independent of current prices or in the other words, they follow the random walk hypothesis. Global issues tend to have an impact on capital markets around the world. Therefore, the objective of this study is to assess the effect of global issues on the movements of expected returns in the Indonesian capital market from January 1, 2022, to June 30, 2022. The sample of 755 listed firms is used to test whether the expected returns have a random pattern during the observation period. The results of runs tests and variance ratio test show that the expected return movements are not random. On those results, the weak form of the efficient market hypothesis is rejected, and it can be concluded that the capital market in Indonesia for this period is inefficient. The findings of this study imply that the information about global issues does not affect the market. The success of the Indonesian government’s strategy in dealing with global issues (including the Covid-19 pandemic) in the form of a vaccination program and also followed by excellent fiscal and monetary policies has led to more predictable returns in the capital market. Moreover, investors can set their portfolios to get extraordinary returns as the market is more predictable.
LITERATE THOUGHT: A COMMENTARY
Authors: V. Paul Peter
Published: October 2022

A number of d/Deaf and hard of hearing students, as well as other students in special education programs, have difficulty accessing academic content information that, traditionally, has been presented in written language in print and electronically (e.g., textbooks, other school materials, etc.). Because this information represents what students need to know, there will be a large gap in their knowledge base, and students will not have ample opportunities to develop a high level of literate thought. That is, students will not be able to represent and manipulate information, solve problems, or develop other higher-level critical thinking skills. This article presents a case for the reconceptualization of literacy—namely, a broadening of our traditional notion of literacy as being able to read and write a written language. This reconceptualization, emphasizing literate thought, requires a discussion of types of literacies and an understanding of constructs such as access and interpretation, illiteracy, and listening comprehension. Also discussed is the intertwinement of literate thought and Universal Design for Learning. The article concludes with questions for further exploration and dialogue.
A STUDY ON THE USE OF METACOGNITIVE READING STRATEGIES BY LEARNERS WITH PSYCHOSOMATIC CONDITION
Authors:   Department of English, School of Social Sciences and Languages, VIT University, Vellore, Tamil Nadu, India, Monika M. , Devi V. Anitha ,   Department of English, School of Social Sciences and Languages, VIT University, Vellore, Tamil Nadu, India
Published: October 2022

The study examines the influence of metacognitive reading strategies in developing the reading comprehension skills among ESL (English as Second Language) learners with the psychosomatic condition. Qualitative and quantitative research was used in the present study and it was an experimental study. Reading comprehension skill is crucial to language learners for effective decoding of the information. Metacognitive reading strategies aid the learners to develop reading strategies for effective comprehension of the text. The metacognitive strategies like pragmatic and analytical strategies were used in this research to improve the intensive and evaluative reading comprehension skills. The participants of the study are a hundred and twelve (Male and Female) tertiary level ESL learners from the undergraduate engineering program. The experiment intends to improve the reading comprehension skills among the samples with psychosomatic conditions. The sampling method used in the study was purposive sampling. Data collection tools like questionnaires, pre-test, post-test, and post-feedback questionnaires were used in the study. An android-based application will be created with the activities and instructional materials and it was circulated to the learners. Metacognitive reading activities were given to the learners through the application and data was collected. Results were quantitatively analyzed using statistical tools from the data collected through the application. The results of the present study were indicative that there is a significant improvement in the learners’ reading comprehension skills due to the intervention of metacognitive reading strategies.
Analisis Pengaruh Kualitas Produk, Persepsi Harga, Distribusi, dan Citra Merek pada Kepuasan Pelanggan Air Minum Dalam Kemasan Quelle di Kota Cilegon
Authors:   Universitas Mercu Buana, Jl. Meruya Selatan No.1, Jakarta Barat, DKI Jakarta 11650, Indonesia, Nurul Annisa , Mulyowahyudi Alugoro ,   Universitas Mercu Buana, Jl. Meruya Selatan No.1, Jakarta Barat, DKI Jakarta 11650, Indonesia
Published: October 2022

Penelitian ini dilakukan untuk menganalisis pengaruh kualitas produk, persepsi harga, distribusi, dan citra merek terhadap kepuasan pelanggan Air Minum Dalam Kemasan (AMDK) Quelle. Penelitian ini menggunakan pendekatan kuantitatif melalui metode survei. Survei dilakukan dengan membagikan kuesioner kepada 105 pelanggan end user AMDK Quelle sebagai sampel responden. Ada lima variabel yang digunakan, yaitu kualitas produk, persepsi harga, distribusi, dan citra merek sebagai variabel bebas dan kepuasan pelanggan sebagai variabel terikat. Data yang terkumpul dianalisis dengan menggunakan regresi linier berganda menggunakan uji t pada α = 0,05. Hasil penelitian menunjukkan bahwa kualitas produk, persepsi harga, distribusi, dan citra merek secara simultan berpengaruh positif dan signifikan terhadap kepuasan pelanggan. Secara parsial, kualitas produk, persepsi harga, distribusi, dan citra merek juga berpengaruh positif dan signifikan terhadap kepuasan pelanggan. Variabel yang berpengaruh paling besar terhadap kepuasan pelanggan adalah persepsi harga, diikuti dengan kualitas produk, dan distribusi. Sementara citra merek memiliki pengaruh paling kecil terhadap kepuasan pelanggan.
Pendidikan Kewirausahaan, Disrupsi Inovasi, dan Peluang Kewirausahaan pada Mahasiswa Universitas DR. Soetomo Surabaya
Authors:   Universitas DR. Soetomo Surabaya Jl. Semolowaru No.84, Menur Pumpungan, Surabaya, Jawa Timur 60118, Indonesia, Harwiki Wiwiek
Published: October 2022

Penelitian ini bertujuan untuk mengidentifikasi karakteristik pendidikan kewirausahaan, disrupsi inovasi dan peluang kewirausahaan, serta menghasilkan model. Pendekatan kualitatif digunakan dalam penelitian ini, dengan teknik analisis deskriptif eksploratif untuk mengidentifikasi bagaimana pendidikan kewirausahaan, disrupsi inovasi bisa mendorong peluang kewirausahaan. Informan terdiri atas 8 mahasiswa semester 6, telah lulus menempuh mata kuliah Kewirausahaan dan Koperasi dari 8 Fakultas berbeda (Teknik, Sastra, Ilmu Administrasi, Hukum, Kependidikan, Ilmu Komunikasi, Pertanian dan Ekonomi&Bisnis), Universitas DR. Soetomo Surabaya. Hasil penelitian membuktikan bahwa karakteristik pendidikan kewirausahaan dicerminkan oleh adanya tujuan pendidikan, sarana dan prasarana, materi pengajaran dan metode pengajaran. Karakteristik disrupsi inovasi bisa diawali dengan usaha kecil, pada posisi rendah dan pasar baru. Sedangkan karakteristik peluang kewirausahaan meliputi situasi, keyakinan dan perilaku. Model yang dihasilkan membuktikan bahwa (1) pendidikan kewirausahaan dan (2) disrupsi inovasi mendorong ke arah peluang kewirausahaan yang lebih baik.
Kuliah kewirausahaan, berpengaruhkah pada minat Berwirausaha?
Authors:   Universitas Ahmad Dahlan, Jl. Kapas 9, Semaki, Umbulharjo, Yogyakarta 55166, Rintasari Nugraheni , Hidayat Effan ,   Universitas Ahmad Dahlan, Jl. Kapas 9, Semaki, Umbulharjo, Yogyakarta 55166
Published: October 2022

This study aims to examine the effect of entrepreneurship courses, income expectations, and entrepreneurial characteristics on entrepreneurial interest. The object of the research was student participants in the Ahmad Dahlan University Accountant concentration class who had taken six courses related to Entrepreneurship. The number of respondents was 53.The results showed that entrepreneurship courses, income expectations, and the characteristics of entrepreneurship explained 37.2% of the factors affecting entrepreneurial interest. Hypothesis testing using the regression test shows the results that college entrepreneurship and income expectations influence the interest in entrepreneurship and the characteristics of entrepreneurship have no effect. This shows that universities have the opportunity to cultivate curriculum related to entrepreneurship. Because there are indications that the interest in entrepreneurship can be grown through entrepreneurship courses
Analisis Norma Subjektif, Sikap, dan Intensi Penduduk Jabodetabek dalam Membeli Beras Organik
Authors:   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya JL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430, Indonesia, Amanda V.T Bella , Bawapratama Choky Rais ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya JL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430, Indonesia, Naomi Krisan Felicia ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya JL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430, Indonesia, Pratiwi Nadya ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya JL. RA. Kartini (TB Simatupang), Cilandak Barat Jakarta Selatan, Jakarta 12430, Indonesia
Published: October 2022

Penelitian ini bertujuan untuk menguji perluasan Teori Perilaku Terencana (TPT) dalam konteks pembelian beras organik, yaitu hubungan antara norma subjektif, sikap, dan intensi dalam hal membeli beras organik oleh konsumen di Jabodetabek. Kuesioner dengan metode kuantitatif diadopsi dan diadaptasi dari studi sebelumnya. Kuesioner diberikan kepada pelanggan di kota Jakarta, Bogor, Depok, Tangerang, dan Bekasi. Sebanyak 220 kuesioner yang terkumpul dianalisis dengan menggunakan analisis regresi berganda dan sederhana. Norma subjektif dan kesadaran akan kesehatan terbukti berpengaruh terhadap sikap membeli beras organik di Jabodetabek. Sikap, persepsi ketersediaan beras, dan pentingnya harga juga terbukti secara positif berpengaruh dan signifikan terhadap intensi membeli beras organik di Jabodetabek. Intensi tersebut secara positif berpengaruh dan signifikan terhadap frekuensi pembelian beras organik di Jabodetabek.
Faktor-Faktor yang Mempengaruhi Penggunaan Pembayaran Seluler di Jabodetabek
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Hawari Abdullah , Adriansyah Adriansyah ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Brian Brian ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Grace Simanjuntak Destrina ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Susanto Rinaldo ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya
Published: October 2022

Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang mempengaruhi niat penggunaan (intention to use) pembayaran seluler di Jabodetabek. Metode pengumpulan data dilakukan menggunakan kuisioner kuantitatif. Analisis data secara statistik yang dilakukan meliputi analisis deskriptif, uji validitas dan reliabilitas, ANOVA, serta regresi linier. Hasil penelitian mengindikasikan trust of safe to use dan usefulness secara langsung mempengaruhi intentiontouse dari pembayaran seluler di Jabodetabek. Sedangkan easetouse, convenienceofmobility, compatibility dan mobile payment knowledge tidak secara langsung mempengaruhi intention to use. Hasil penelitian ini bermanfaat bagi pemangku kepentingan pembayaran seluler, terutama bagi manajemen untuk meningkatkan pangsa pasar dalam persaingan industri yang ketat dengan kompetitor.
Pembentukan E-Loyalty dengan Framework Kepercayaan - Multidimensi pada E-Commerce di Indonesia
Authors:   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Yasin Arby Y. , Yoga Wirawan Henry ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi,Universitas Prasetiya Mulya, Fahima Hanifa Muhammad ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi,Universitas Prasetiya Mulya, Bernadeta Novi ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi,Universitas Prasetiya Mulya, Burman Srimiaty ,   Program Magister Manajemen, Sekolah Bisnis dan Ekonomi,Universitas Prasetiya Mulya
Published: October 2022

Bisnis startup merupakan model bisnis yang sudah tidak asing di masyarakat Indonesia. Dengan persaingan ketat di pasar e-commerce, Aplikasi/Website ZXC dengan program Flash Sale “Shake shake” di tahun 2018 mendapatkan antusiasme di masyarakat. Antusiasme ini menunjukan loyalitas pelanggan dalam memilih e-commerce. Penelitian ini bertujuan untuk melihat kualitas informasi dan perlindungan keamanan sebagai faktor utama hubungan antara tingkat kepercayaan dengan loyalitas konsumen terhadap e-commerce yang digunakan, serta melihat hubungan antara berbagai macam dimensi kepercayaan. Metode yang digunakan dalam penelitian ini adalah pengumpulan data dan sampling, dengan 330 orang responden, dengan menanyakan beberapa aspek dan memberikan penilaian skala 1-7 yang akan dianalisis menggunakan multiple regression analysis. Hasil penelitian menunjukkan tingkat dimensi kepercayaan dalam mempengaruhi loyalitas pelanggan terhadap e-commerce, dimana reputasi toko merupakan faktor yang paling berpengaruh terhadap loyalitas pelanggan dalam memilih e-commerce sebagai tempat bertransaksi online.
Analisa Kebutuhan Pengembangan SDM Volunteer Tourist dengan Program Pemberdayaan Masyarakat Daerah
Authors:   Fakultas Ekonomi dan Bisnis, Universitas Airlangga, Jalan Airlangga 4-6, Surabaya Indonesia 60285, Masulah Rizka Susanti , Agustina Tri Siwi ,   Fakultas Ekonomi dan Bisnis, Universitas Airlangga, Jalan Airlangga 4-6, Surabaya Indonesia 60285
Published: October 2022

Sejak kemunculan volunteer tourist, fenomena ini banyak mendapatkan kritik dan keraguan akan efek atau dampak yang diberikan pada masyarakat lokal program yang menjadi objek pemberdayaan masyarakat. Kritik ini disebabkan dengan melihat pada kualifikasi relawan yang berpartisipasi lebih banyak tidak memiliki pengetahuan, pengalaman dan skill (keahlian) pemberdayaan masyarakat sama sekali. Dengan pendekatan Training Need Analysis (TNA) Penelitian ini bertujuan untuk dapat menganalisa dan mengetahui kebutuhan pengembangan SDM yang dibutuhkan oleh relawan sebelum melakukan pekerjaan pemberdayaan masyarakat pada daerah 3T (Terdepan, Terluar Tertinggal). Penelitian dilakukan dengan menggunakan metode kualitatif untuk bisa mendapatkan eksplorasi yang mendalam terhadap kebutuhan pengembangan pengembangan SDM. Data dikumpulkan dengan wawancara mendalam terhadap sebelas relawan yang berpartisipasi pada salah satu NGO penyelenggara volunteer tourist pada salah satu daerah 3T di Indonesia. Data menunjukkan variasi kemampuan dan pengetahuan SDM dalam melakukan pekerjaan pemberdayaan masyarakat. Variasi berdampak pada adanya perbedaan kebutuhan pengembangan SDM berdasarkan pengetahuan dan keahlian yang dimiliki. Pada SDM relawan yang belum memiliki pengetahuan, pengalaman dan keahlian di bidang pemberdayaan perlu mendapatkan pengembangan mengenai dasar – dasar, prinsip dan teknis pekerjaan pemberdayaan masyarakat. Pengembangan Analisa yang mendalam dan terintegrasi dibutuhkan organisasi untuk dapat menemukan kebutuhan pelatihan yang dibutuhkan oleh SDM relawan
Pengaruh Influencer Type dan Disclosure of Sponsorship pada Konten Bersponsor di Instagram
Authors:   Fakultas Ekonomi dan Bisnis, Universitas Airlangga, Jalan Airlangga 4-6, Surabaya Indonesia 60285, Destyana Nadhira Pratiwi , Premananto Gancar Candra ,   Fakultas Ekonomi dan Bisnis, Universitas Airlangga, Jalan Airlangga 4-6, Surabaya Indonesia 60285
Published: October 2022

opulernya penggunaan pemasaran influencer menjadikan influencer media sosial dan keefektifannya ketika melakukan endorse produk penting untuk dipertimbangkan oleh pemasar. Terlebih di beberapa negara peraturan kebijakan baru-baru ini mewajibkan influencer media sosial untuk mengungkapkan konten bersponsor saat menggunakan bentuk nativeadvertising. Penelitian ini menguji pengaruh influencertype (micro- vs. macro-influencer) dan disclosureof sponsorship (disclosure vs. non-disclosure) pada unggahan bersponsor mereka di media sosial Instagram terhadap product attractiveness dan purchaseintention menggunakan uji MANOVA. Penelitian ini menggunakan desain faktorial 2x2 pada 120 partisipan perempuan Generasi Millenial. Dalam penelitian ini, berdasarkan uji interaction effect, micro-influencer yang mengungkapkan unggahan bersponsor secara disclosure menghasilkan purchaseintention yang tinggi dibandingkan influencertype dan disclosureof sponsorship lainnya. Berdasarkan uji main effect, disclosureof sponsorship secara disclosure oleh influencer menghasilkan product attractiveness dan purchaseintention yang tinggi dibandingkan secara non-disclosure, sedangkan influencertype yang menghasilkan purchaseintention yang lebih tinggi adalah micro-influencer
Behavioral Factors Analysis in Investment Decision-Making
Authors:   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Dumohar Anggiat , Aryotejo Dimas ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Djohan Nielson ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Tirto Peter ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Mulia Rizki ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430
Published: October 2022

This study focuses in investigating behavioral factors that affect individual investment decision who actively trading in Indonesia stocks exchange. The paper emphasizes in less developed financial markets (Indonesia) to occupy literature gap. Seven (7) human financial behavior which categorized as heuristic biases are measured by numerous questions under online questionnaire, to examine the relationship between trait anxiety, overconfidence, trait anger, self-monitoring, herding factor, anchoring/adjustment, and availability bias with investment decision. To test the hypothesis, sample of 168 Indonesian Stocks Exchange investors are analyzed using statistical methods of regression and correlation analysis. Relationship of financial behavior biases and investment decision is analyzed on the research. The result indicates that overconfidence and self-monitoring are related with investment decision while trait anger, trait anxiety, herding effect and availability bias, and anchoring and adjustment are not related.
Covid-19’s Impact on Financial Planning in Short-Term and Long-Term Perspectives
Authors:   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Simanungkalit Imelda , Pangestu Fabiola Widi Dwi ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Simbolon Kevin ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Astikawati Rina ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Zulfikar Zulfikar ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430, Rijanto Arief ,   Universitas Prasetiya Mulya, Cilandak Campus, Jl. RA. Kartini (TB Simatupang), Cilandak Barat, Jakarta Selatan 12430
Published: October 2022

This research investigates psychological factors including underconfidence bias, analytical/intuitive decision-making approach, self/significant other orientation, and time orientation that influence people's financial planning in short and long-term perspectives under the Covid-19 pandemic situation. The data were collected from the online survey by using a convenience sampling technique. A total of 331 valid responses were scaled on 7 Likert-type questions. Multiple regression analyses were performed in analyzing the hypotheses. This study provides empirical insight into the relationship between psychological factors and financial planning in the short and long-term perspectives. The results indicate both financial planning in short and long-term perspectives is positively associated with analytical decision-making style, time orientation, self, and other orientation. Underconfidence bias is negatively associated only with long-term financial planning but, in contrast, is not supported by evidence to a short-term perspective. Finally, intuitive-decision making is not correlated with financial planning in short-term perspective. This study helps individuals to design better personal financial planning and financial institution to develop more relevant financial services for targeted clients. This study uses consumer behavior's perspective and figures out the gap in consumer behavior literature, especially investigating the underconfidence bias effect on Indonesian's financial planning.
Design and Pharmacology of Dual Angiotensin-Converting Enzyme and Neutral Endopeptidase Inhibitors
Authors: De Lombaert Stephane , Chatelain Ricardo E. , Fink Cynthia A. , Trapani Angelo J.
Published: October 2022

Angiotensin converting enzyme (ACE) inhibitors are important therapeutic agents for the management of hypertension and congestive heart failure (CHF). Although the therapeutic effects of neutral endopeptidase (NEP) inhibitors (i.e. blood pressure lowering, natriuresis, diuresis) in patients have been unimpressive, experimental and clinical evidence suggests that concomitant blockade of the renin-angiotensin­ aldosterone system (RAAS) would be beneficial. Therefore, with the expectation that combined inhibition of ACE and NEP could provide therapeutic advantages over selective inhibitors of either enzyme in the treatment of hypertension and CHF, a substantial research effort has been devoted to the design of single molecules that display dual ACE/NEP inhibitory activities. Such endeavor benefited from the opportunity that both enzymes belong to the same zinc metalloprotease superfamily. This review outlines various recent successful approaches in the design of dual inhibitors, summarizes the pharmacological properties of selected compounds, and provides an outlook on the therapeutic potential of these new agents for the treatment of human cardiovascular diseases.
Organic Nitrates: New Concepts for Old Drugs
Authors: Bertolini Giorgio , Sala Alberto
Published: October 2022

Organic nitrates have been in therapeutic use for the treatment of angina pectoris for over a century. Recently it was reported that the release of nitric oxide (NO), mediated by a cascade of biochemical events, is responsible for the pharmacological activity of these compounds. The organic nitrates most commonly used, (glyceryl trinitrate (GTN), isosorbide dinitrate (ISDN), isosorbide-5-mononitrate (IS-5-MN) and nicorandil), are useful for the treatment of stable, unstable and Prinzmetal's angina pectoris, for congestive heart failure and myocardial infarction. Nowadays new applications for these compounds, such as ocular hypotension and the protection of gastric mucosa, are emerging.

However, the classical organic nitrates are characterized by undesirable side-effects, such as nitrate tolerance, strong_hypotension, reflex tachycardia and headaches. During the last decade, the search for new organic nitrates with reduced side effects and improved oral bioavailability has greatly intensified. The structural modifications studied in order to solve these problems and the structure-activity relationships for each new class of organic nitrates are reported in this review.
Use of Terpenoids to Control Helminths in Small Ruminants
Authors: Mesquita-Sousa Dauana , Miro Victoria , Silva Carolina R. , Pereira Juliana R. F. , Costa-Júnior Livio M. , Virkel Guillermo , Lifschitz Adrian
Published: October 2022

Gastrointestinal nematodes affect the animal's health and cause economic
losses in meat, milk, and wool production. Essential oils and their terpenoids have been
shown to effectively control gastrointestinal nematodes and may be an alternative to
control gastrointestinal nematodes. The great advantage of terpenoids is the possibility
of acting on the parasite in a multidirectional way on the neuromuscular system and
body structures of nematodes. The current chapter describes the pharmacological basis
of the combination of terpenes and synthetic anthelmintics as an alternative for
increasing antiparasitic efficacy. It is necessary to evaluate if these combinations show
antagonist, additive or synergic effects at the pharmacokinetic and pharmacodynamic
levels. The physicochemical properties, pharmacokinetic features and potential drug drug interactions at the metabolism or transport level of monoterpenes may be relevant
for obtaining effective concentrations against different nematodes. In this context, the
prediction of absorption, distribution, metabolism and excretion (ADME) is essential to
optimize the anthelmintic action of these compounds. The rapid absorption and
elimination of monoterpenes after their oral administration may directly influence the
drug concentration level attained at the target parasites and the resultant
pharmacological effect. Therefore, investigations on the dose schedule, administration
route and type of pharmaceutical formulation are necessary. The integration of in vitro
assays, in silico analysis, and in vivo pharmaco-parasitological studies are relevant to
corroborate the kinetic/metabolic interactions and the efficacy of bioactive natural
products combined with synthetic anthelmintics
Fuzzy Systems and Applications from an Engineer’s Perspective (Fuzzy Textual Data Classification - Case Study)
Authors: Wajeed Mohammed Abdul
Published: October 2022

Soft computing has arisen as a standard presuming perspective; fuzzy ideashave advanced as imperative in the field of processing. The present chapter wouldexpect to motivate and support the reader by giving all the necessary flavorsempowering him to seek after and exude creative thoughts in the field of the fuzzyframework. The chapter presents the fundamental fuzzy ideas, including the operationsperformed on uncertainty sets. Fuzzy ideas and operations are contrasted with crispysets for the better cognizance of the pursuers, specifically the naive. How theprobabilistic and fuzzy frameworks (level of truthness) vary would be underscored withsufficient situations. Uncertainty, vagueness in the data, and historical crispy data whenutilized later, would connect some vulnerability with it; an embodiment of suchvulnerability and its need to consider in the processing is managed in detail. Differentfuzzy membership functions commonly used are explored here. The underlyingterminology (core, support and boundary) and its significance in the membershipfunctions are explored. In the last segment of the section, text categorization (TC)application utilizing the fuzzy ideas in processing is investigated. The features in TCare transformed into fuzzy collections (soft, hard and blended) as feature reduction.Gaussian function is employed in the process of obtaining the fuzzy collections.Itemized steps during the time spent treating word-based data classification are talkedabout.
Increasing Performance of Boolean Retrieval Model by Data Parallelism Technique
Authors: Rawat Mukesh , Pratap Preksha , Gupta Manan , Sharma Hardik
Published: October 2022

Information retrieval (IR) is to identify documents of non-uniform behaviorthat fulfill information requirements from the huge repository (maintained in computersystems). Different models have been defined to retrieve/fetch information. Forexample, the Boolean model, the Statistical model, which focuses on the vector spaceand probabilistic retrieval, and the Linguistic and Knowledge-based retrieval models.The Boolean model is defined as the “perfect match” model. If the queries are notaccurate, they retrieve/fetch some irrelevant documents. This is called the precision (p)rate, which is the proportion of the relevant retrieved documents. The Boolean methodprovides good techniques to elaborate or concise a query. The Boolean method workswell for the search process because of the clarity between the concepts. The Booleanretrieval model processes the queries in which terms of the queries are in the form ofBoolean expressions, that is, in which terms of the user query combined with AND(&),OR(||), and NOT(!) operators. The model views documents in the form of invertedindexes. The key concept of an inverted index is to maintain a dictionary of terms. Forevery term, there is a collection of documents in which the term occurs. Posting is acollection of documents in which a term occurs. The list is known as the postings list(or inverted list), and all the postings lists are collectively called postings. But as the number of documents is increased, the postings of documents are alsoincreased, and processing these documents becomes time-consuming; so to resolve thisproblem, a multithreaded model is proposed in which the postings list is broken downinto different chunks and processes, due to which Boolean operation between postingsin accordance with Boolean query becomes faster. Using this data parallelismtechnique, the performance of the Boolean Retrieval Model is increased.
Malignant Mesothelioma
Authors: Takinishi Yasutaka , Tanji Mika , Yang Haining , Carbone Michele
Published: October 2022

Malignant mesothelioma often develops because of exposure to asbestos. The global incidence and mortality of mesothelioma remain unclear because many developing countries do not report it or the data they report are unreliable. Asbestos usage increased over centuries and reached its peak in 1970s. By the 90s the use of asbestos had been banned or tight regulated in many western countries, including the U.S. Asbestos usage continues to increase exponentially in developing countries. In addition to occupational asbestos exposure, environmental exposure to asbestos and other mineral fibers can cause mesothelioma. Asbestos carcinogenesis is largely caused by the chronic inflammatory process driven by the extracellular release of HMGB1 by mesothelial cells and macrophages. In addition, germline mutations of the BRCAassociated protein 1(BAP1) gene and less frequently of other tumor suppressor genes and DNA repair genes can cause or predispose to mesothelioma. Germline BAP1 mutant carriers develop additional malignancies during their lifetime. Fortunately, several of these malignancies, including mesothelioma, are less aggressive than their sporadic counterparts. BAP1 is also the gene most frequently mutated somatically in sporadic mesothelioma underscoring the critical role of this gene in suppressing mesothelioma growth. The preventive measure aimed at reducing occupational exposure to asbestos and environmental exposure to various carcinogenic fiber effectively reduces the incidence of mesothelioma. Carriers of germline BAP1 mutations benefit from close follow-up for early cancer detection. Because they may be susceptible to asbestos carcinogenesis, they should avoid trades or living in areas where carcinogenic fibers may be present.
The Role of IARC in Causation of Occupational Diseases: Case Study of the Carcinogenic Evaluation of Crystalline Silica
Authors: Goldsmith David F.
Published: October 2022

The importance of causation of occupational diseases and the role of the
International Agency for Research on Cancer (IARC) are discussed in this chapter. As
a case study, the process by which silica dust was judged a known human carcinogen
by IARC is reviewed. Silicosis is a chronic occupational lung disease known to be
caused by inhaling crystalline silica, and the pulmonary cancer risk after the diagnosis
of silicosis is a part of the IARC review of evidence. Laboratory animal evidence and
mechanistic findings supporting IARC evaluation are also described. There remains a
need to explore the association between silica exposure and other nonlung tumors,
especially gastrointestinal cancers. The Occupational Safety and Health Administration
(OSHA) developed a new regulatory standard that lowered the permissible exposure to
50ug/m3 in 2016. OSHA labeled silica as a known human carcinogen because of the
IARC assessment. Occupational medicine leaders need to address several current silica
dust problems such as silicosis/coal workers pneumoconiosis among coal miners, acute
silicosis and auto-immune diseases among countertop workers, and intervention
programs to lower silico-tuberculosis among South African miners. Future research
studies need good silica dust monitoring estimates and high-quality industrial hygiene
samples to evaluate the associations between silica exposure and many diverse
diseases.
Biodiesel Production from Algae Oil
Authors: Yaşar Fevzi
Published: October 2022

In this study, biodiesel production was investigated by the transesterificationreaction from algae oil. For biodiesel production, the oil obtained from Chlorellaprotothecoides type algae grown in freshwater with 5% thermal water was added tofully automated closed-loop system high-tech pyramid photobioreactors and adaptedfor oil production, which had a low acid value (0.23 mg KOH/g). Because of this, basecatalyst transesterification was applied. For the transesterification reaction, 99.7%purity of methyl alcohol as alcohol and 99.9% purity of potassium hydroxide (KOH)was used as a catalyst. In order to determine the most suitable conditions for theproduction of biodiesel from algae oil, a series of laboratory-scale preliminaryexperiments have been carried out. As a result of the optimization studies, the 6:1methyl alcohol/oil molar ratio, the use of KOH up to 0.75% of the oil by mass, thereaction temperature of 60 °C, and the reaction time of 60 minutes were determined asthe most suitable conditions for biodiesel production. Under these conditions, 96.4%methyl ester yield was obtained, and kinematic viscosity and density values of the finalbiodiesel product were measured as 4.493 mm2/s and 882 kg/m3. As a result of thephysical and chemical analysis of the produced biodiesel, it has been determined that ithas an ester content of over 96% and that the free and total glycerol content withmethanol, mono-, di- and tri-glyceride is well below the maximum values specified inthe EN 14214 and ASTM 6751 biodiesel standards. However, properties such asviscosity, density, flash point, cetane number, acid value, sulfur and water content werefound to be compatible with the specified standards. In addition, besides having thestandard fuel properties of the produced biodiesel, its high cetane number (57) andgood cold filter clogging point (-11 oC), makes it an important alternative diesel enginefuel.
Use of Microbial Fuel Cells (MFCs) in Food Industry Wastewater Treatment
Authors: Yılmazoğlu Mesut
Published: October 2022

Since MFC degrades simple carbohydrates i.e. glucose, acetate, andbutyrate, and countless organic substances such as pig wastewater, domesticwastewater, and manure sludge waste, the biochemical energy generated by thecatalytic reactions of microorganisms and converts the waste produced into energy. Itpromises a sustainable wastewater treatment to balance the operating cost. This chapteris a review of the advantages of microbial fuel cell treatment of food industrywastewater, which creates high organic pollution in the industrial field.
Development of Algae Oil Production With Ecological Engineering
Authors: Koyunoğlu Cemil , Karaca Hüseyin
Published: October 2022

It is well known that the use of algae-based fuels is not widespread as theydo not meet the necessary fuel standards. The amount of oil products obtained fromtraditional biomass sources exceeds that obtained from algae. However, ecology canprovide more assistance in increasing the current efficiency of oil production fromalgae. Depending on the species, effective results can be obtained through theproduction of fatty acids and biofuels. The amount of fuel produced by a single speciesshould be weighted against the amount of oil produced by a combination of species.The presence of genetic diversity, particularly in two types of algae mixtures, isunavoidable in order to improve the quality of fuel produced. The lipid obtained undergenetically diverse population is highlighted in this study.
Microalgae Culture
Authors: Işık Oya , Uslu Leyla
Published: October 2022

Energy is becoming one of the most expensive production inputs nowadays.Energy reserves are starting to run out and their polluting effects have been seenaround the world. Therefore, there is an urgent need for renewable energy sourcesinstead of fossil fuels. One of these energy sources is algae biomass, which is seen aspromising for biofuel production.
Different Species of Algae
Authors: Koyunoğlu Cemil , Karaca Hüseyin
Published: October 2022

The oil yield of many microalgae species varies. Therefore, the selection ofalgae species is important. Features that are effective in selecting the appropriatespecies for algae production are growth and productivity, minimum contamination, andeasy harvesting. However, the percentages of carbohydrate, fat, and protein in thestructure of algae provide preliminary information about the oil yield to be obtainedfrom that algae species.
Introduction to Localized Controlled Drug Delivery Systems (LCDDSs)
Authors: Hoseinpour Samin , Zarshad Shadi
Published: October 2022

Localized controlled drug delivery systems (LCDDS) that can control drug
release profiles to ensure high therapeutic efficacy and reduced side effects are highly
desired in the pharmaceutical and biomedical fields. Biodegradable drug delivery
depots have been investigated over the last several decades as the means to improve
tumor targeting and severe systemic morbidities associated with intravenous
chemotherapy treatments. These localized therapies exist in a variety of factors
designed to facilitate the controlled drug delivery, directly to the disease site, sparing
off-target tissue toxicities. Many of these depots are biodegradable and designed to
maintain therapeutic concentrations of drugs at the tumor site for a prolonged period of
time. The depots are placed inside the body through a single implantation procedure,
sometimes simultaneously with the tumor excision surgery, following the complete
release of the loaded active agent. Even though localized depot delivery systems have
been widely investigated, only a small subset have demonstrated curative preclinical
results for cancer applications, from which just a few have reached commercialization.
Nanoparticles-mediated Localized Controlled Drug Delivery Systems (LCDDSs)
Authors: Naghib Seyed Morteza , Hoseinpour Samin , Zarshad Shadi
Published: October 2022

Nanoparticles (NPs) and nanostructures can facilitate multianalyte detection,
imaging and selective targeting of therapeutic molecules to cancer cells. This method
increases the drug dose and maximizes at the anticipated location, and the healthy
cells/tissues and their environments are protected simultaneously. To develop the
targeting potential of therapeutic molecules, the surface and size characteristics of NPs
should be improved, thereby enhancing their targeting effectiveness and circulation
time. Here, we have highlighted recent advances and progress in smart stimuli-sensitive
nanocarriers synthesized to improve the efficiency and localization of drugs compared
to unmodified drugs. Multifunctional NPs could enhance the controlled release and
targeting ability of drugs/therapeutic agents/biomolecules. The smart multifunctionality
establishes versatile NPs, moreover, localized controlled drug delivery systems
(LCDDSs) are promising and considerably increase the efficiency of therapy and
diagnosis (theranosis) in pharmaceutical and biomedical science/engineering.
Genome-Wide Association Studies (GWAS)
Authors: Noor Ul Ayan Hafiza , Tariq Muhammad
Published: October 2022

Genome-wide association studies (GWAS) are designed to find associations
between genomic variants and a phenotype, usually a complex multifactorial disease.
The idea for association studies in a large cohort was floated after linkage analysis,
which proved extremely successful in the identification of causative genes for rare
disorders, but it did not come up to expectations in the case of common complex
disorders where causative alleles are less frequently aggregated in families. Ever since
their advent in 2005, GWAS have transformed gene identification ventures in complex
disease genetics over the past fifteen years, giving rise to several powerful associations
for complex traits and disorders. Association studies are based on the “common disease
common variant” hypothesis which assumes that genomic variation with low
penetrance and high population frequency are involved in the causation of common
complex disorders. Although GWAS, complemented with the downstream functional
assessment of the variants, have been successful in identifying novel disease-causing
genes and biological mechanisms, the field has also received intense criticism over the
years, especially its failure in tracing the so-called ‘missing heritability’. Therefore,
further functional studies are mandatory to precisely establish a link between risk
alleles and a phenotype. This chapter broadly covers an introduction of GWAS, their
successes and limitations, and various important factors affecting the design and
results, followed by challenges in the post-GWAS era.
Regenerative Medicine
Authors: Qayyum Hajra , Bakhtiar Syeda Marriam
Published: October 2022

Regenerative medicine (RM) is defined as a replacement and revival of
human cells, tissues, or organs to reinstate or reconstruct their normal physiology. RM
is regarded as a solution to provide healthy substitutes for a malfunctioning/failed
organ or a tissue. It is emerging as the suitable substitute for organ transplantation.
Transplantation seems impractical due to the limited availability of donors as
significant disparities lie between the number of patients that require transplantation
and the availability of organs from the donor, so there was a gap created. Therefore, to
comply with these needs, RM has emerged as a new science to create biological
replacements and exploit the body's ability of regeneration to recover and sustain
normal function in diseased and damaged tissues. This chapter overviews RM in terms
of adopted strategies, its clinical applications in organ engineering along with inherited
challenges and their plausible solutions.