bluuebunny/crossref_metadata_2025 huggingface dataset:
Dudjom Rinpoche's Vajrakīlaya Works: A Study in Authoring, Compiling, and Editing Texts in the Tibetan Revelatory Tradition
Authors: Cantwell Cathy
Published: February 2022

It is often assumed that a revelation must be new and innovative, and that the point of a new sacred text must be to revitalize the heritage. Yet, in the Tibetan Nyingma Treasure Revelatory tradition, the ongoing vitality of textual production often has more to do with the fresh blessings rather than altogether novel content. This book is the first to analyse precise continuities and changes in comparing the new and the old, considering examples of the creation and development of tantric revelations, including further reworkings in subsequent generations. In doing so, the focus enlarges to encompass materials from the broader religious heritage, as well as from specific lineages of related visionary lamas. By identifying such exact linkages and departures, it is possible to answer questions both of how and why developments may occur, not limiting the purview merely to the individual stories of the virtuoso lamas producing the books, but looking also to the tantric communities of which they are a part. The case studies in the book stem from the prolific writings of the famous twentieth-century scholar-lama Dudjom Jigdral Yeshe Dorje Rinpoche, who contributed to numerous revelatory traditions of the past, as well as producing his own revelations. They concern a single tantric deity, Vajrakīlaya, the most popular Nyingma deity, whose tantras and ritual practices stem from the earliest formulations of Tibetan tantric Buddhism, and who is closely connected with the culture heros and founding fathers of the Nyingmapa. This particular focus gives us the opportunity to discover patterns in the creation of new tantric texts which have significance beyond the specific examples.
What the Buddha Thought
Authors: Gombrich Richard
Published: February 2022

In What the Buddha Thought, Richard Gombrich argues that the Buddha was one of the most brilliant and original thinkers of all time. Intended to serve as an introduction to the Buddha’s thought, and hence even to Buddhism itself, the book also has larger aims: it argues that we can know far more about the Buddha than it is fashionable among scholars to admit, and that his thought has a greater coherence than is usually recognised. It contains much new material. Interpreters both ancient and modern have taken little account of the historical context of the Buddha’s teachings; but by relating them to early brahminical texts, and also to ancient Jainism, Gombrich gives a much richer picture of the Buddha’s meaning, especially when his satire and irony are appreciated. Incidentally, since many of the Buddha’s allusions can only be traced in the Pali versions of surviving texts, the book establishes the importance of the Pali Canon as evidence. The book contains much new material. The author stresses the Buddha’s capacity for abstraction: though he made extensive use of metaphor, he did not found his arguments upon it, as earlier thinkers had done. He ethicized and radically reinterpreted older ideas of karma (human action) and rebirth. Similarly, building on older texts, he argued for the fundamental importance of love and compassion, and analysed fire as a process which could stand as a model for every component of conscious experience. Morally, the Buddha’s theory of karma provided a principle of individuation and asserted each individual’s responsibility for his own destiny. To make the book completely accessible to the general reader, the author provides an introductory section of ‘Background Information,’ for easy reference.
Needs, parenting practices, and dissemination of information on social-emotional skills and development of infants
Authors: Costa Priscila , Andrade Paula Rosenberg de , Cintra Thatianne Ferreira Gomes , Cordeiro Samara Macedo , Pettengil Myriam Aparecida Mandetta , Veríssimo Maria De La Ó Ramallo
Published: February 2022

ABSTRACT Objectives: to describe the development of a technological innovation designed to identify needs, parental practices, and disseminate information on social-emotional skills and development of infants from the perspective of family members of infants on the social-emotional development of children. Methods: a report on the development of an innovation consisting of an educational group and a card game on social-emotional skills and development of infants. A spider-web concept map, content analysis and the Bioecological Theory of Human Development as a theoretical reference were used for data analysis. Results: the educational group and card game enabled the identification of information needs on child behavior and playing, and parenting practices focused on affectionate interactions, responsive caregiving, and socialization. Conversation with experienced parents, educational groups, apps, and health consultations were desirable dissemination strategies. Conclusions: the educational group and the card game represent an innovative, low-cost technology with potential for large-scale application in primary healthcare services.
Social entrepreneurship in the professional training in Nursing
Authors: Backes Dirce Stein , Colomé Juliana Silveira , Mello Giovana Batistella de , Gomes Regina Celia de Castro , Lomba Maria de Lurdes Lopes de Freitas , Ferreira Carla Lizandra de Lima
Published: February 2022

ABSTRACT Objectives: to assess the knowledge and practices that stimulate social entrepreneurship in the professional training of Nursing students. Methods: qualitative exploratory-descriptive study carried out with 44 Nursing students from a University in the South Region of Brazil. Data were collected between May and August 2021, through individual online interviews. The participants were students of nursing course in the 6th semester or above, who had previously participated in teaching, research, or university outreach activities on entrepreneurship. Results: the data was organized and analyzed according to the thematic analysis technique and resulted in three thematic categories: Meanings of social entrepreneurship, Factors that sparked social entrepreneurship, and Recognizing oneself as an entrepreneurial nurse. Final Considerations: the knowledge and practices that stimulate social entrepreneurship in the professional training of Nursing students are associated with teaching, research and university outreach activities that allow concrete experiences in the living and dynamic world of communities.
Prevalence of and risk factors for dynapenic abdominal obesity in community-dwelling older adults: a cross-sectional study
Authors: Araújo Fabrícia Coelho de , Silva Karoline Sampaio da , Ohara Daniela Gonçalves , Matos Areolino Pena , Pinto Ana Carolina Pereira Nunes , Pegorari Maycon Sousa
Published: February 2022

Abstract This article aims to identify the prevalence of and factors associated with dynapenic abdominal obesity (DAO) in older adults in a city in the northern region of Brazil. A cross-sectional study was conducted with 382 community-dwelling older adults in Macapa, Amapa, Brazil. Socioeconomic, clinical, and health information were collected using a structured form. DAO was defined as a combination of dynapenia (handgrip strength of < 26 kgf for men and < 16 kgf for women) and abdominal obesity (abdominal circumference > 102 cm for men and > 88 cm for women). Descriptive and inferential analyses were performed using chi-squared tests, Student’s t-tests, and a Poisson regression. The prevalence of DAO was 10.73%. In the preliminary bivariate analysis, the variables of age range, marital status, number of diseases, functional disability for basic and instrumental activities of daily living, gait speed, and level of physical activity met the established criterion. The final model indicated that only gait speed was a predictor of DAO in older adults. DAO affects nearly 11% of community-dwelling older adults from northern Brazil; gait speed was a predictor of DAO and could be a useful tool for managing and monitoring this population’s health.
Desigualdades sociais e alimentação complementar na América Latina e no Caribe
Authors: Cavalcanti Allyevison Ulisses Alves , Boccolini Cristiano Siqueira
Published: February 2022

Resumo Este artigo tem como objetivo avaliar o papel das desigualdades sociais nos padrões de alimentação complementar nos países da América Latina e do Caribe. Trata-se de um estudo ecológico que utilizou dados agregados de inquéritos de base populacional. A unidade de análise da pesquisa foram 16 países da América Latina e do Caribe com informações disponíveis. Foram selecionados como desfechos a prevalência dos seguintes indicadores de alimentação complementar: introdução alimentar de alimentos sólidos, semissólidos e pastosos” (IASSP), “diversidade alimentar mínima” (DAM), “frequência alimentar mínima” (FAM) e “alimentação mínima aceitável” (AMA). As diferenças da prevalência dos indicadores entre os quintis de riqueza mais ricos e mais pobres foram calculadas de forma absoluta e relativa. Comparando os quatro indicadores de alimentação complementar, o IASSP teve o melhor desempenho, com 10 países, entre os 11 avaliados, apresentando prevalência acima de 80%. O indicador com pior desempenho foi o AMA, com apenas um país, entre os oito avaliados, com prevalências acima de 60%. Na quase totalidade dos países, a população mais pobre possuía prevalências de indicadores de alimentação complementar menores que os mais ricos.
Desrespeitos e abusos, maus tratos e violência obstétrica: um desafio para a epidemiologia e a saúde pública no Brasil
Authors: Leite Tatiana Henriques , Marques Emanuele Souza , Esteves-Pereira Ana Paula , Nucci Marina Fisher , Portella Yammê , Leal Maria do Carmo
Published: February 2022

Resumo Estudos sobre desrespeitos e abusos/maus tratos/violência obstétrica durante gestação, parto e puerpério têm aumentado nas últimas décadas. Entretanto, os pesquisadores interessados na temática se deparam com muitas dificuldades teóricas e metodológicas. Nesse sentido, o objetivo do presente estudo consiste em discutir e refletir sobre como questões relacionadas a definição e terminologia, mensuração e políticas públicas no Brasil têm dificultado a pesquisa da temática, assim como a mitigação desses atos. O primeiro problema abordado foi a falta de consenso em relação a terminologia e definição desse construto. Essa situação provoca um efeito em cascata, com a utilização de instrumentos de aferição não validados que implicam falta de precisão e comparabilidade entre os estudos. Outra questão mencionada é a falta de estudos explorando as consequências desses atos na saúde da mulher e do recém-nascido, configurando uma das principais lacunas sobre o tema atualmente. A ausência de estudos causais impacta a tomada de decisão em saúde, prejudicando a elaboração de políticas públicas específicas.
Prevalence of common mental disorders among Brazilian workers: systematic review and meta-analysis
Authors: Coledam Diogo Henrique Constantino , Alves Taciane Aurora , Arruda Gustavo Aires de , Ferraiol Philippe Fanelli
Published: February 2022

Abstract The aim of the present study was to summarize the prevalence of common mental disorders (CMD) among Brazilian workers through a systematic review and meta-analysis. Searches were conducted in SciELO, LILACS, PubMed, Scopus, and Web of Science. Articles were included if they had; an observational design, a sample of Brazilian workers, used a validated instrument and cut-off to assess CMD, and provided the prevalence value. A random-effect meta-analysis using professional categories as subgroups and a meta-regression were conducted. In total, 89 studies were included, with a total of 56,278 workers from 26 professional categories. The overall pooled prevalence of CMD was 0.30 (95%CI: 0.27-0.34), varying from 0.07 to 0.58. Professional categories that presented higher prevalences of CMD were: Prostitutes 0.58 (95%CI: 0.51-0.65), Social Educators 0.54 (95%CI: 0.50-0.59), Banking Workers 0.45 (95%CI: 0.44-0.47), Ragpickers 0.45 (95%CI: 0.40-0.49), and Teachers 0.40 (95%CI: 0.32-0.48). No other variable in addition to profession was associated with prevalence of CMD in the meta-regression analysis. Workers from the most affected professional categories should be monitored to prevent social, occupational, and health impairment from CMD.
Monitoring pond water quality to improve the production of Labeo rohita (Hamilton, 1822) in Bannu Fish Hatchery of Bannu district, Khyber Pakhtunkhwa province; An Implications for artificial fish culture
Authors: Masood Z. , Hasan Z. , Gul H. , Zahid H. , Hassan H. U. , Sultan R. , Khan W. , Safia  , Titus K. , Ullah A.
Published: February 2022

Abstract The water quality parameters of a fish pond are essential to be managing properly under control for successful operations of fish culture. Improper management of pond water quality during the juvenile stages can create stressful conditions to produce various harmful diseases, which may decrease the fish quality and results in low profits. The present study was aimed to monitored important water quality parameters of nursery ponds of Labeo rohita culturing in Bannu fish hatchery. The study duration was 75 days extends from 10th June to 24th August 2019 for the successful culture of this specie which can play a significant role in breeding season. Furthermore, the concentration of some heavy metals like copper (Cu), nickel (Ni), manganese (Mn), iron (Fe), cadmium (Cd), and zinc (Zn) in pond water and fry stages of this species was also determined. The data obtained from all water quality parameters were analyzed expressed as range, mean and standard deviation using MS Excel 2013. The obtained results of 75 days study revealed that the water pH & temperature, electric conductivity, total dissolved solids (TDS), and total dissolved oxygen (DO) of pond water samples were found within a tolerable limit except salinity and dissolved ammonia concentration were not permissible for fish growth. The average concentration of heavy metals in pond water exhibited descending order Fe>Ni>Mn>Zn>Cd>Ni, which was found in acceptable ranges. Whereas, the average values of heavy metals in fry stages were in the order of Zn>Fe>Ni>Cu>Cd>Mn, and found within the recommended values of WHO/FAO. Thus, it was concluded from this study that good water quality is a precondition, maintaining balanced levels of water quality parameters is fundamental for both the health and growth of fish culture which is quite necessary for assuring increased fish productivity. It is recommended to monitor and assess water quality parameters on a routine basis for promoting healthy fish culture.
A equivalência entre o Princípio de Maximização de Entropia e o Princípio de Minimização de Energia
Authors: Lima Nathan Willig , Duarte Sergio
Published: February 2022

Neste trabalho, apresentamos a discussão original de Gibbs sobre a equivalência entre as condições de equilíbrio, a dizer, a condição de máxima entropia para uma energia determinada e a condição de mínima energia par uma entropia determinada – as quais são apresentadas como teoremas pelo autor. Na sequência, mostramos como tal discussão aparece em livros didáticos contemporâneos que apresentamos a Termodinâmica a partir de suas leis (lei zero mais as três leis). Comparamos tal apresentação com a discussão feita por Callen, em sua abordagem postulacional da Termodinâmica. Mostramos que parte da discussão de Gibbs foi perdida mesmo nos livros que abordam as leis. Ademais, discutimos que a abordagem de Callen não enfatiza o fato de que apesar de os princípios serem equivalentes, termalizar um sistema composto por processos distintos (um com energia constante e outro com entropia constante) conduz a diferentes valores de temperatura. Além de resolver o problema analiticamente, apresentamos uma análise gráfica do problema. Ao final, discutimos implicações para o ensino de termodinâmica.
Tempo utilizando computador como discriminador de obesidade, sedentarismo e fatores de risco cardiovascular em universitários
Authors: Guerra Heloísa Silva , Brugnoli Adriana Vieira Macedo , Melo Raiana Rodrigues Costa , Moriguchi Emílio Hideyuki , Pattussi Marcos Pascoal , Costa Juvenal Soares Dias da
Published: February 2022

Resumo: Introdução: Os universitários apresentam maior risco de adotar o comportamento sedentário em virtude da própria rotina, a qual requer muito tempo dedicado às aulas e a utilização frequente do computador para os estudos. Essa situação tem se tornado preocupante porque o comportamento sedentário tem sido associado a desfechos adversos em saúde, como mortalidade e doenças crônicas não transmissíveis. Objetivo: Este estudo teve como objetivo analisar o tempo despendido com o uso do computador como discriminador da obesidade, do sedentarismo e de fatores de risco cardiovascular em universitários. Método: Trata-se de estudo transversal realizado com 2.275 acadêmicos de cursos da área da saúde de uma fundação pública do estado de Goiás. Os dados foram obtidos por meio da aplicação de um questionário composto por variáveis sociodemográficas, relativas ao curso e a aspectos comportamentais e de saúde. A variável de desfecho foi o tempo utilizando o computador (TC). Identificaram-se o poder discriminatório e os pontos de corte do TC para os desfechos de interesse por meio das curvas Receiver Operating Characteristic (ROC) com IC95%. Resultado: O tempo médio usando o computador para estudos, trabalho ou lazer foi de 3,90 horas/dia para mulheres e 3,82 horas/dia para homens. A área sob a curva ROC entre o TC e o sedentarismo foi de 0,54 (IC95% 0,51-0,58) para mulheres e 0,56 (IC95% 0,50-0,63) para homens. Já para a hipertensão arterial sistêmica (HAS), foi de 0,57 (IC95% 0,50-0,64) para mulheres. Os melhores pontos de corte relacionados a essas condições foram 3,5 e 4,5 horas, respectivamente. Conclusão: O TC apresentou boa capacidade preditiva para discriminar o sedentarismo e a HAS entre universitários. Sugere-se que a diminuição do TC e sua substituição por atividades ativas possam contribuir para a melhoria do perfil de saúde e a qualidade de vida dos acadêmicos.
Qualidade de vida em voz e sintomas emocionais pré e pós-tireoidectomia
Authors: Oliveira Gustavo Batista de , Oliveira Thais Jejesky de , Santos Marco Homero de Sá , Rocha Ricardo Mai , Guimarães Michelle Ferreira , Azevedo Elma Heitmann Mares
Published: February 2022

RESUMO Objetivo Correlacionar a qualidade de vida em voz e sintomas de ansiedade e depressão pré e pós-tireoidectomia. Método Estudo observacional, longitudinal, prospectivo e quantitativo. Participaram 20 pacientes, com média de idade de 54 anos, submetidos à tireoidectomia, ao exame visual laríngeo e aos questionários Qualidade de Vida em Voz e Escala Hospitalar de Ansiedade e Depressão nos momentos: pré-operatório, 1 semana e 3 meses pós-tireoidectomia, com maior prevalência do sexo feminino (85%; n=17) e de tireoidectomia parcial (70%; n=14). Resultados Não houve diferença estatística quanto à qualidade de vida em voz entre os momentos, porém observaram-se menores escores no pré-operatório, com destaque para o domínio físico. Houve traço leve de ansiedade no pré-operatório com redução após 1 semana e aumento pós três meses. Houve correlação negativa moderada entre o domínio físico do QVV e a subescala de ansiedade e o escore total da HADS pós 1 semana e entre o domínio total do QVV com o escore total da HADS pós 1 semana, correlação negativa fraca entre o domínio total do QVV e a subescala de ansiedade da HADS pós 1 semana e o escore total da HADS pós 3 meses. Conclusão Os pacientes avaliados neste estudo autopercebem sua qualidade de vida relacionada à voz como positiva. Traços leves de ansiedade foram identificados, com redução no pós-operatório uma semana e aumento pós três meses. A autopercepção de melhor qualidade de vida em voz no pós-operatório relaciona-se, de forma fraca, com a redução dos níveis de ansiedade.
Ação e formação da terapia ocupacional social com os jovens na escola pública
Authors: Pan Lívia Celegati , Lopes Roseli Esquerdo
Published: February 2022

Resumo Tomando o pioneirismo do METUIA/UFSCar no cenário brasileiro quanto a proposições terapêutico-ocupacionais para a escola pública e às demandas advindas da questão social, esta pesquisa buscou compreender o que foi produzido pelo grupo em termos de ação e formação em terapia ocupacional social em escolas públicas, com foco na juventude popular urbana, num período compreendido entre 1998 e 2017. Para tanto, foram realizadas entrevistas com 10 terapeutas ocupacionais que atuaram pelo METUIA/UFSCar, um encontro coletivo com essas profissionais para discutir a temática, a aplicação de questionários com ex-estudantes de graduação que passaram por estágio profissionalizante junto ao METUIA/UFSCar e entrevista individual com setes deles. As análises dos resultados indicam uma proposta de formação que, de um lado, vem sensibilizando terapeutas ocupacionais para o trabalho com a juventude pobre, apreendendo a centralidade da escola pública para ela e, de outro, produzindo ações que buscam a ressignificação da escola e do seu espaço, com produção de sentido e pertencimento, que possam contribuir para o desejo de permanência e/ou retorno aos estudos desses jovens. Pontua-se a incorporação de seus referenciais teóricos e metodológicos nas experiências de trabalho daqueles que passaram pelo grupo, terapeutas ocupacionais e alunos egressos, assim como a inspiração para produções semelhantes em outras universidades do país. Conclui-se pela relevância do que vem sendo feito pelo METUIA/UFSCar, especialmente naquilo que é a formação de terapeutas ocupacionais e práticas que se voltem para demandas relacionadas à desigualdade social, que ainda é uma marca da Educação Básica no Brasil.
Autopercepção do paciente com doença pulmonar obstrutiva crônica sobre seu desempenho ocupacional em tempo de pandemia de COVID-19
Authors: Vasconcelos Roberta Fontenele de , Frota Marília Ximenes Freitas , Albuquerque Valéria Barroso de , Munguba Marilene Calderaro da Silva
Published: February 2022

Resumo Introdução A Doença Pulmonar Obstrutiva Crônica (DPOC) é caracterizada pela limitação progressiva do fluxo aéreo. Os pacientes também desenvolvem manifestações sistêmicas que determinam o declínio progressivo da capacidade funcional. Objetivo Conhecer a autopercepção do paciente com DPOC sobre seu desempenho ocupacional destacando a influência da pandemia de COVID-19 no seu cotidiano. Método Pesquisa de natureza descritiva e abordagem qualitativa, tendo como técnica a análise de conteúdo na modalidade temática. A amostra foi constituída de nove pacientes com DPOC atendidos no programa de manutenção pós-reabilitação pulmonar em hospital de referência de saúde em cardiopneumologia. A coleta dos dados ocorreu de junho a agosto de 2020, mediante roteiro de entrevista semiestruturada, por meio de chamadas telefônicas. As entrevistas gravadas foram transcritas e submetidas à análise do conteúdo, por meio da análise temática. Resultados As ocupações cotidianas percebidas com dificuldade de serem realizadas em decorrência da DPOC foram sono, trabalho, participação social, lazer, além de Atividades de Vida Diária (AVD) – mobilidade funcional, banho, higiene pessoal, vestir e atividade sexual – e Atividades Instrumentais da Vida Diária (AIVD) – gerenciamento do lar e fazer compras. As ocupações limitadas pela DPOC foram ainda mais impactadas pelas medidas restritivas causadas pela COVID-19. Conclusão Com base na compreensão das dificuldades do paciente com DPOC em realizar suas ocupações, foi possível conhecer o quanto a DPOC repercute no desempenho ocupacional e interfere nas mais diversas ocupações que trazem significado e propósito à vida. A pandemia de COVID-19 limitou ainda mais o envolvimento do paciente com DPOC nas suas ocupações significativas.
Sistemas de saúde, mecanismos de governança e porosidade governamental em perspectiva comparada
Authors: Ribeiro José Mendes , Vaitsman Jeni , Motta José Inácio Jardim
Published: February 2022

O artigo apresenta uma análise comparada de 10 países selecionados sobre as relações entre governança participativa, perfis socioeconômicos e sistemas de saúde com resultados sanitários e de Indicadores de Governança Global. As fontes principais foram bases de dados produzidas e/ou compiladas pelo Banco Mundial. O modelo analítico se apoia em enfoque institucionalista para tratar de proteção social e governança participativa. Governança participativa, como utilizada, recobre as noções de participação social, porosidade governamental e regulação responsiva. Os resultados mostram uma sólida convergência entre perfis socioeconômicos mais distributivos, sistemas sanitários com maior financiamento público e universalismo e melhores indicadores de governança. Esta análise reforça os argumentos sobre trajetórias institucionais socialmente virtuosas e sujeitas a reforços positivos capazes de produzir melhores resultados sociais e políticos ao longo do tempo.
A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice
Authors: Song Cheng J. , Li Zhang , Ahmed Ummey Khalecha Bintha , Bland Sarah J. , Yashchenko Alex , Liu Shanrun , Aloria Ernald J. , Lever Jeremie M. , Gonzalez Nancy M. , Bickel Marisa A. , Giles Cory B. , Georgescu Constantin , Wren Jonathan D. , Lang Mark L. , Benveniste Etty N. , Harrington Laurie E. , Tsiokas Leo , George James F. , Jones Kenneth L. , Crossman David K. , Agarwal Anupam , Mrug Michal , Yoder Bradley K. , Hopp Katharina , Zimmerman Kurt A.
Published: February 2022

Significance Statement

It is widely accepted that injuries to cilia mutant mice accelerate the rate of cystic kidney disease. However, cellular factors that accelerate cystic disease are unknown. By performing single-cell RNA sequencing of all CD45+immune cells, we found that the subtypes and gene expression profiles of adaptive immune cells are significantly altered among non-injured, aged cystic mice; injury-accelerated cystic mice; and noncystic controls. Surprisingly, deletion of all adaptive immune cells reduced cystic disease in the injury-accelerated model but had no effect on cystic disease in the non-injured model. This differential rescue may be due to unique adaptive immune cell subtypes and ligands that are only present in the injury-accelerated model of cystic disease.

Background

Inducible disruption of cilia-related genes in adult mice results in slowly progressive cystic disease, which can be greatly accelerated by renal injury.

Methods

To identify in an unbiased manner modifier cells that may be influencing the differential rate of cyst growth in injured versus non-injured cilia mutant kidneys at a time of similar cyst severity, we generated a single-cell atlas of cystic kidney disease. We conducted RNA-seq on 79,355 cells from control mice and adult-induced conditionalIft88mice (hereafter referred to as cilia mutant mice) that were harvested approximately 7 months post-induction or 8 weeks post 30-minute unilateral ischemia reperfusion injury.

Results

Analyses of single-cell RNA-seq data of CD45+immune cells revealed that adaptive immune cells differed more in cluster composition, cell proportion, and gene expression than cells of myeloid origin when comparing cystic models with one another and with non-cystic controls. Surprisingly, genetic deletion of adaptive immune cells significantly reduced injury-accelerated cystic disease but had no effect on cyst growth in non-injured cilia mutant mice, independent of the rate of cyst growth or underlying genetic mutation. Using NicheNet, we identified a list of candidate cell types and ligands that were enriched in injured cilia mutant mice compared with aged cilia mutant mice and non-cystic controls that may be responsible for the observed dependence on adaptive immune cells during injury-accelerated cystic disease.

Conclusions

Collectively, these data highlight the diversity of immune cell involvement in cystic kidney disease.
Enforcamento Homicida Mascarado como Suicídio: Revisão Integrativa
Authors: Lessa de Souza Maia Gabriel , Do Nascimento Silva Pedro Henrique , Gonçalves Bezerra Daniele
Published: February 2022

Estima-se que um a cada mil casos de enforcamento seja de natureza homicida, contudo avalia-se que esse dado é subestimado pelo mascaramento de homicídios como suicídio. Esta revisão objetiva analisar os achados necroscópicos em enforcamentos de etiologia homicida e identificar seus sinais de alerta de interesse médico-legal. Esta pesquisa trata-se de uma revisão bibliográfica integrativa de relatos de caso, dos quais foram selecionados 6 artigos que reportaram um total de 8 casos de enforcamentos homicidas. O resultado da revisão demonstrou que os enforcamentos de etiologia homicida comumente exigem que o assassino tenha vantagem física sobre a vítima, para minimizar ou evitar reação desta. Houve fratura das estruturas do pescoço na metade dos casos analisados, sendo mais comum a fratura do osso hioide, da cartilagem tireoide e da cartilagem cricoide. Os principais sinais de alerta de importância à necrópsia envolvem o sulco de enforcamento, as reações vitais da vítima e lesões que não se relacionam com o mecanismo de morte do enforcamento.
Supervivencia de 12 especies de árboles nativos en plantaciones de restauración en la selva estacionalmente seca
Authors: Marquez Torres Jose Flavio , Martínez-Garza Cristina
Published: February 2022

Antecedentes: La selva estacionalmente seca se puede recuperar usando plantaciones de restauración. La selección de especies para las plantaciones depende de su desempeño exitoso en las condiciones adversas de los sitios degradados.
Hipótesis: Las especies leguminosas de estados sucesionales tempranos muestran mayor sobrevivencia en sitios degradados.
Especies de estudio: Doce especies de árboles nativos de la selva estacional.
Sitio y años de estudio: Pastizales excluidos de la ganadería en Quilamula, Tlaquiltenango, Morelos, México durante 28 meses de julio del 2017 a octubre del 2019.
Métodos: Plantaciones experimentales para las 12 especies (N = 1,080 plantas). Se registró la supervivencia en octubre del 2017, junio y octubre del 2018 y en octubre del 2019
Resultados: Las especies sucesionales tempranas mostraron mayor supervivencia (27 %) que las tardías (20 %). Las leguminosas mostraron mayor supervivencia (25 %) que las no-leguminosas (22 %). Las especies tempranas no-leguminosas y las tardías leguminosas presentaron una supervivencia similar y esta fue mayor (> 30 %) que la de las especies leguminosas tempranas (< 18 %).
Conclusiones: Para asegurar el éxito de plantaciones de restauración y acelerar la velocidad de recuperación se sugiere sembrar mezclas de especies sucesionales tempranas ( i.e ., Dodonaea viscosa Jacq. y Leucaena leucocephala (Lam.) De Wit) y la mayor cantidad posible de especies sucesionales tardías, leguminosas y no-leguminosas.
EFFECTS OF INITIAL SHEAR STRESS AND VIBRATION FREQUENCY ON THE DYNAMIC STRENGTH CHARACTERISTICS OF SATURATED CLAY
Authors: Zhang Jian , Sun Yangguang , Cao Jiuting , Shi Baocun
Published: February 2022

Initial shear stress is inevitable in actual engineering slopes, subgrades and foundations. The soils exhibit different dynamic characteristics under an initial shear stress. The dynamic strength characteristics of saturated clay under cyclic loading were studied through a dynamic triaxial test of remoulded clay in the Wenchuan area. The effects of the failure criterion, initial shear stress and vibration frequency on the dynamic strength characteristics of saturated clay were also analysed. The results showed that the strain failure criterion with a strain value of 2.5 % or the transitional strain εtp can reflect the soil damage realistically and evaluate the dynamic strength of the soil objectively. εp = 2.5 % can be used to replace εp = εtp when the dynamic strength parameter of the saturated clay was calculated under seismic loading equivalent failure vibration times. The dynamic strength parameters of the saturated clay under different earthquake magnitudes were calculated by introducing the equivalent failure vibration times of the soil under seismic loading, thereby providing data support for the stability analysis of the clay foundation under seismic loading. The initial shear stress and vibration frequency have a considerable effect on the dynamic strength of saturated clay. Under the same vibration frequency, the larger the initial shear stress is, the smaller the required dynamic stress is for the soil to break, and the smaller the dynamic strength parameter is. The existence of the initial shear stress reduces the dynamic strength of the soil. Under the same vibration times, the higher the vibration frequency is, the greater the required dynamic stress is for the soil to break, the larger the dynamic strength parameter is, and the greater the dynamic strength of the soil is.
Geri kazanılmış agregalı betonun betonarme binaların deprem performansına etkisinin incelenmesi
Authors: FIRAT ALEMDAR Zeynep , KURT Yavuz
Published: February 2022

Geri kazanılmış agrega kullanılarak üretilen betonun (sürdürülebilir beton) yeni inşa edilecek betonarme çerçeve veya perde + çerçeve olarak projelendirilmiş binalarda dikkate alınmasını inceleyen bu çalışmada, geleneksel beton ve sürdürülebilir betondan elde edilen binaların şekildeğiştirme temeline dayalı performans değerlendirmesi yapılmıştır. Çalışma kapsamında %30 oranında geri kazanılmış agrega içeren sürdürülebilir beton ve C30/37 dayanım sınıfına sahip geleneksel beton kullanılarak üretildiği kabul edilen 8 katlı ve 5 açıklıklı yapılar Türkiye Bina Deprem Yönetmeliği’ne (TBDY 2018) göre doğrusal olmayan statik itme analizi yöntemi ile analiz edilmiştir. Yapılan analizler sonucunda taşıyıcı sistem elemanlarında kat seviyelerinde oluşan kesme kuvvetleri ve katlar arası göreli ötelenme değerleri belirlenmiştir. Sürdürülebilir betondan elde edilen yapıların geleneksel betonlu yapılar gibi deprem etkilerine karşı gereken performansı sağladığı görülmüştür. Ayrıca sürdürülebilir betonun geleneksel betona göre daha elastik bir davranışa sahip olması nedeni ile Türkiye Bina Deprem Yönetmeliğinde yapıların üretildiği beton malzeme farklılığının dikkate alınarak, yapının özellikle geri dönüşümlü beton kullanılarak inşa edildiği durumlarda, daha elastik olarak tasarlanması gerektiği önerilmektedir.
Kırınım teorisindeki bir takım iki boyutlu problemlerin çözümlenebilmesi için efektif bir metot
Authors: DUR Osman
Published: February 2022

İki boyutlu integral denklemler günümüzde pek çok farklı mühendislik ve bilimsel çalışmada sıklıkla kullanılmaktadır. Bu denklemlerin nümerik ve analitik yöntemler kullanılarak geniş frekans spektrumları boyunca çözülmesinde; cisimlerin elektriksel boyutları ve geometrik yapılarının karmaşıklığı göz önüne alınır.

Bu makale bir takım integral denklemlerinin çözülebilmesi için efektif bir çözüm önerisi sunar. Kusursuz elektrik iletken metal plakalar tarafından gerçekleşen kırınım teorisinin çeşitli problemleri bu integral denklemlerine indirgenmiştir. Böylece, frekans parametrelerinin isteğe bağlı değerlerinin ve ekran boyutlarının anlaşılabilmesi için integral denklemlerinin çözümüne dair bir metot önerilmektedir.
Zaman serileri analizi için optimize ARIMA-YSA melez modeli
Authors: ERTURAN Mahmut Burak , MERDİVENCİ Fahriye
Published: February 2022

Zaman serileri analizi alanında son yıllarda birden çok modelin bir arada kullanıldığı melez modeller ortaya konulmaktadır. Literatürde yer alan en önemli melez model sınıflarından biri ARIMA-Yapay Sinir Ağları (YSA) melez model sınıfıdır. Gerçek hayatta karşılaşılan zaman serilerinin genellikle doğrusal ve doğrusal olmayan özellikleri bir arada taşıması, ARIMA-YSA melez modellerin tahmin performanslarının yüksek olmasını sağlamaktadır. Bu çalışmada optimizasyon tabanlı özgün bir ARIMA-YSA melez model ortaya konulmaktadır. İleri sürülen melez model, zaman serisini doğrusal ve doğrusal olmayan iki serinin toplamı olarak kabul etmektedir. İki aşamalı modelin ilk aşamasında, doğrusal ve doğrusal olmayan bileşenlerin elde edilmesi amacıyla ARIMA ve YSA modelleri ile gerçek seri bir en küçük kareler optimizasyonu sürecinden geçmektedir. İkinci aşamada ise doğrusal bileşenin hataları doğrusal olmayan bileşene aktarılarak doğrusal olmayan bileşen revize edilmekte ve YSA ile tekrar modellenmektedir. Tahmin performansının tespiti için Optimize ARIMA-YSA (OptAA) melez modeli, ARIMA, YSA, literatürdeki başlıca melez ARIMA-YSA modelleri ve rassal yürüyüş modeli ile karşılaştırılmaktadır. Uygulama aşaması için literatürde sıklıkla kullanılan üç farklı zaman serisi seçilmiştir. Elde edilen sonuçlar OptAA melez modelin özellikle görece kısa dönem tahmin performansının diğer modellere göre oldukça yüksek olduğunu ve zaman serisi analizi alanında oldukça güçlü bir yöntem olduğunu göstermektedir.
Aprendizaje percibido de estudiantes universitarios en cursos en modalidad presencial y mixta: un estudio comparativo
Authors: Sotelo-Castillo Mirsha Alicia , Barrera-Hernández Laura Fernanda , Echeverria-Castro Sonia Beatriz , Ramos-Estrada Dora Yolanda
Published: February 2022

The research findings regarding the level of learning in face-to-face and b-learning courses have indicated opposite results. Due to this, the present study was carried out with the aim of comparing the level of learning perceived by university students who attended courses in face-to-face and b-learning modalities (blended learning). Two hundred and nineteen students (134 women and 85 men) from different educational programs participated, 45% of the students who took courses in face-to-face mode and 54% in mixed mode (b-learning), who responded to an online instrument that measured: perception of learning acquired on the subject taken, level of development of technological skills and development of communication skills and collaborative work after completing the subject. In the results, it was found a statistically significant difference in the level of self-reported learning by students who took the class on a mixed and face-to-face modality, where the students of the face-to-face courses perceived higher learning about the subject than those who took the class in a b-learning mode. In addition, it was found that the modality described in 24% perceived learning by the students in the subjects studied.
Competencia Digital Docente en el País Vasco durante la pandemia del COVID-19
Authors: Portillo-Berasaluce Javier , Romero Ainara , Tejada Eneko
Published: February 2022

The objective of this research is to measure the perception that teachers had about their own performance when they were forced to carry out an Emergency Remote Teaching due to the COVID-19 pandemic. A questionnaire was provided to teachers of every educational stage in the Basque Country (Child, Primary and Secondary Education, Professional Training and Higher Education) obtaining a total of 4,586 responses. The statistical analysis of the data shows that the greatest difficulties reported by educators are shortcomings in the training of teachers in digital skills, as well as a lack of resilience of the system and / or lack of a 'plan B' in extraordinary situations. The existing digital divide between teachers based on their gender, age and type of school should be highlighted. Another worrying result is the lower technological competence in lower educational levels, which are the most vulnerable in remote teaching. These results invite us to reflect on the measures to be taken to improve equity, social justice and resilience of the educational system.
Las TIC como vía de comunicación familia-escuela en la educación compensatoria
Authors: Rodríguez-Caballero Cristina de las Nieves , Fernández-Olaskoaga Lorea
Published: February 2022

The coexistence of social diversity in Spain has led to a situation of socio-economic inequality. This situation prompted the first Compensatory Educational Centers to originate from the Spanish educational system in the 1960s, whose purpose is to support the socio-educational insclusion of students. The main aim of this research is related to the possible association between socio-economic differences and a higher rate of school failure, taking into account the difficulties arising from the Covid-19 situation as ICTs have been established as the main means of communication. The objective of this study is to bring to light the use of ICT resources as a means of communication in the educational field made by the families of the Andalusian Compensatory Educational Centers, and to contrast them with the use by normative families. The sample comprises students and families from the already mentioned schools of the 2nd cycle of Early Childhood Education. To do this, the access to digital devices, the frequency with which they use the educational platforms iPasen / iSéneca, Classroom, or other alternative routes, and their purposes are analyzed. The information is compiled through questionnaires elaborated ad hoc for the research, where the main results point out specific differences between both populations regarding the access and use of the several digital resources. Finally, it can be concluded that the socio-economic level can be considered a determining factor in the communication between the family and the school.
Tuber Yield and Economics of Potato as Affected by Application of Vermicompost, Mineral Nitrogen and Phosphorus in Southwestern Ethiopia
Authors: Zewide Isreal , Singh Sanjay , Kassa Henok
Published: February 2022

Multi-nutrients deficiency of soil in southwest Ethiopia is among the primary constraints for the very low productivity of potatoes (Solanum tuberosum L.). The combined use of organic and inorganic fertilizers is vital for resolving the common productivity issue. Thus, experiments were performed on potato variety “Belte” in Masha district, southwestern Ethiopia, in both Belg (February to May) as well as Meher (June to October) seasons of 2019 to evaluate the potato response to the vermicompost, mineral phosphorus, and nitrogen’s integrated applications. The experiment had three vermicompost rates with the factorial combination (2.5, 5, 7.5 t/ha) and three recommended rates inorganic NP’s 25%, 50% and 75% (124 kg N/ha and 103 kg P2O5/ha) fertilizer. Results have discovered that 75% inorganic NP and 7.5 t/ha vermicompost’s combined application significantly increase total tuber yield, marketable tuber yield, and individual tuber weight, giving the maximum net benefits and marginal return rate. Thus, it has been discovered from this work that for potato production at Masha area, 7.5 t/ha vermicompost with inorganic NP’s 75% recommended dose’s combined applications are best-integrated nutrient management options.
Pathogenicity of Sclerotium rolfsii Isolates Causing Stem and Root Rot Disease of Cowpea Vigna unguiculata (L.) Walp and Management Using Trichoderma Species
Authors: Dania Victor Ohileobo , Henry Enwongu Uso
Published: February 2022

Sclerotium rolfsii is a soil-borne pathogen causing stem and root rot disease with concomitant reduction in growth and yield of cowpea. Therefore, this study evaluated pathogenicity of S. rolfsii isolates and the management of root and stem rot disease using Trichoderma species. The isolates were obtained from cowpea rhizosphere and pathogenicity was determined using a susceptible cowpea genotype ITI0K–815-5 in an experiment arranged in a completely randomized design with four replications. In vitro and in vivo trials of Trichoderma spp. against a selected virulent isolate Sclerotium rolfsii (SR06) were conducted in the laboratory and screenhouse, respectively. All nine S. rolfsii isolates were pathogenic to the cowpea genotype, while isolate SR 06 was the most virulent with 85.56% infectivity rate. Treatments with T. virens and T. atroviride application reduced the disease incidences to 22.2% and 25.3%, respectively, compared to synthetic funguforce fungicide. Plants that were inoculated and treated with T. atroviride had significantly higher yield of 435 kg/ha than other treatments (p<0.037). Findings from this research encourages the incorporation of Trichoderma species in the integrated management of S. rolfsii pathogen and the incidence of stem and root rot disease in cowpea.
In vitro GCase activity assay (total cell lysate) v1
Authors: Bertoli Federico
Published: February 2022

Glucocerebrosidase is a lysosomal enzyme that catalyzes the hydrolysis of glucosylceramide (GlcCer), a membrane glyco-sphingolipid, to ceramide and glucose. This assay detects GBA activity by using a fluorogenic substrate that reacts with cell lysates previously treated with or without CBE (GBA1 inhibitor).
[RETRACTED] Keoni CBD Gummies Reviews Benefits Does it Really Work Scam or Legit Update 2021 v1
Authors: not provided https://megasupplementsmart.com/goKeoniCBDGummies
Published: February 2022

[RETRACTED]

Keoni CBD Gummies will be the perfect way for you to tackle various health concerns naturally with the functioning mechanism of natural and plant-based substances if you are looking for any natural solution to heal your body and are unable to locate any effective product. These gummies will provide instant relief from a variety of bodily aches and pains, including depression, tension, anxiety, immobility, inflexibility, poor focus, poor concentration, and so on.
THE ENHANCEMENT OF ISLAMIC MORAL VALUES THROUGH SEX EDUCATION FOR EARLY CHILDREN IN THE FAMILY ENVIRONMENT
Authors: Kurdi Muqarramah Sulaiman , Afif Yusmicha Ulya
Published: February 2022

The fast-moving conditions and development of the times, the easy access to mass media at every level requires that parents provide their children with an education. The education aimed at is sex education for children of an early age. The increasing problem of sexual deviancy behavior in the country of Indonesia is that one is the result of a lack of understanding about sexual education. Sex education should certainly be applied at an early age in order to have good morals and not be susceptible to promiscuity. Premature age is a golden phase for children, treatment of them can affect their life into adulthood. The purpose of research is to learn the importance of sexual education in an early-age child morals based on islamic religious views. A research approach uses a qualitative approach for case study methods. Studies reveal sexual education should be given concurrently with a religious basis. Child sexual education needs to be applied by family members as a protection for their child.