bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of FGF23 Levels and Development of Anemia in Patients with Non Dialysis Chronic Kidney Disease
Authors: Alam Professor Dr. Md. Babrul , Prodhan Dr. Md. Jahangir Alam , Hossain Dr. Md. Shahadat , Ahmed Dr. SK Faisal
Published: September 2024

Background: Anemia is one of the common complication of Chronic Kidney Disease that intensifies in grade and severity as eGFR decline which also increases the risks for cardiovascular mortality. The development of anemia and elevated fibroblast growth factor 23 levels are the earliest changes observed in chronic kidney disease. Objective: This study aims to understand the association of FGF23 levels development of anemia in chronic kidney disease patients prior to renal replacement therapy. Methods: This is an analytical type of cross sectional study carried out among 95 respondent'1ged between 18 and 75 years with CKD stage 1-5 before dialysis, divided into two groups- Group I­ comprised of 68 patients and Group 11- included 27 age and sex matched respondents not having CKD, enrolled from two te1tiary-care hospitals, namely- Sir Salimullah Medical College & Mitford Hospital and National Institute of Kidney Diseases & Urology (NIKDU). Socio-demographic status, disease profile and laboratory findings including serum iron, iron binding capacity, ferritin, transferrin saturation, calcium, phosphorus, intact parathormone, vitamin D, eGFR and FGF-23 levels were studied. Result: Mean age of the respondents was 50.1±10.74 (SD) years, mean estimated glomerular filtration rate was 35.92± 22.61 in group I and 91.66± 14.2 in group II. The mean FGF23 level in group I and II were 85.76± 207.54, 21.99± 12.12 pg/mL respectively, serum iron level was 81.61± 39.24 mcg/dL and 95.0± 32.38 mcg/dL in group I and II respectively, serum ferritin level was 225.59± 2 I 2.5 ng/mL and 157.85± 220.89 ng/ml. TIBC was 312.65± 95.83 mcg/dL and 418.85± 118.25 mcg/dL in group I and II respectively. In Group I and II, iron deficiency was found in 23% and 25%respectively when stratified according to serum ferritin level and 26.5% and 22.22% respectively, when stratified according to serum transferrin saturation level. This difference was significant among the group. Serum iron, ferritin, TIBC and TSAT were significantly associated with serum FGF23 levels. Conclusion: Disrupted iron metabolism and high FGF23 levels is commonly found in chronic kidney disease. Clinical laboratory findings have revealed the relation between FGF23 and anemia in no dialysis chronic kidney disease patients.
Prescribing Patterns of Intravenous Artesunate for Severe Malaria and Compliance with National Malaria Treatment Protocol, Gezira State, Sudan
Authors: Ali Arwa Ali Salih Alhaj , Malik Elfatih Mohamed , Hussein Mohammed Taha , Abdelrahman Anwar Mohamemed , Ibrahim Suha Gafar Mohamedkhair
Published: September 2024

Background: Malaria is a major public health problem in Sudan. Severe malaria, due in majority of cases to P. falciparum, poses a real burden on hospitals. This study aims to describe the prescribing pattern of intravenous artesunate (IV-AS) for severe malaria and compliance with national malaria treatment protocol in Gezira State, Sudan. Methods: The study enrolled severe malaria patients who were admitted to the Wad Madani Teaching Hospital during June – August 2022. Patients were verbally consented and followed at hospital level till discharge. Data was recorded on data collection sheet and analyzed using SPSS version 20. Results: Over three months period, 500 patients were diagnosed as having severe malaria based on clinical criteria and the results of thick blood film. The majority were from rural areas and most of them were male. IV-AS was administered for all patients and 71% of patients discharged after administering three doses of artesunate with no serious adverse effects. In 96.4% of patients, the prescription followed the right dosage schedule. The source of the drug was health insurance fund and private sector in 78.4% and 21.6% respectively. The study investigates the prescribing patterns of intravenous artesunate (IV-AS) for severe malaria and compliance with the national malaria treatment protocol in Gezira State, Sudan. A Chi-Square Test of Independence was used to explore associations between gender and the number of IV-AS doses received, as well as between residence (rural vs. urban) and compliance with the dosage schedule. The results showed no significant association between gender and the number of IV-AS doses received (p = 0.915), and no significant association between residence and compliance with the dosage schedule (p = 0.925). These findings suggest that the prescribing patterns and compliance with the treatment protocol are consistent across different genders and between rural and urban patients. Conclusion: Severe malaria patients were treated with IV-AS according to national malaria treatment guidelines with few exceptions. Most patients discharged after administering three doses of artesunate with no serious adverse side effects. Efforts to establish quality assured microscopy and to maintain the current prescription pattern is highly needed.
Disparidades no Aleitamento Materno no Brasil: Um Estudo Ecológico sobre o Aleitamento Exclusivo e seus Determinantes
Authors: Campanharo Luisa , Adelis Sales da Silveira Artur , Bonadio Gonçalves Fabio , Miranda Kaminice Thaís
Published: September 2024

Introdução: O aleitamento materno exclusivo é reconhecido por proporcionar benefícios significativos à saúde da criança e da mãe, como fortalecimento do sistema imunológico, redução da mortalidade infantil, e estreitamento do vínculo mãe-filho. Apesar das recomendações globais para amamentação exclusiva durante os primeiros seis meses de vida, o Brasil enfrenta grandes disparidades regionais nas taxas de aleitamento materno.Objetivo: Este estudo visa analisar as variações regionais na prevalência do aleitamento materno exclusivo em crianças menores de seis meses no Brasil, identificando os fatores que influenciam estas disparidades.Metodologia: Utilizamos uma abordagem de análise descritiva baseada em dados secundários coletados em 2023 pela Secretaria de Atenção Primária à Saúde. A população do estudo incluiu crianças acompanhadas nos serviços de saúde de todo o território nacional, com os dados organizados por região geográfica.Resultados: Os resultados apontaram que a prevalência de aleitamento materno exclusivo foi mais alta no Norte (63%) e mais baixa no Nordeste (51%), com o Centro-Oeste, Sudeste e Sul apresentando prevalências de 60%, 56% e 55%, respectivamente. No total, 56% das crianças brasileiras foram amamentadas exclusivamente.Discussão: A discussão enfoca como as variações regionais podem ser atribuídas a diferenças culturais, socioeconômicas, e na eficácia de implementação de políticas públicas de saúde. Enquanto algumas regiões, como o Norte, demonstram uma adesão maior devido à preservação de práticas culturais e programas locais de incentivo, outras, como o Nordeste, enfrentam barreiras como pobreza e falta de acesso adequado a serviços de saúde, impactando negativamente as taxas de aleitamento.Conclusão: Este estudo destaca a necessidade de políticas de saúde mais personalizadas e sensíveis às especificidades regionais para promover o aleitamento materno exclusivo. A adaptação local dos programas de incentivo e a educação sobre os benefícios da amamentação são essenciais para reduzir as disparidades regionais e melhorar os desfechos de saúde infantil em todo o país.
Study of structure and properties of titanium alloy manufactured by selective electron beam melting using "thin walls" mode
Authors: Filatova A.A. , Tarasova T.V. , Peretyagin P.Yu. , Metel' A.S.
Published: September 2024

The results of research on the powder from the titanium alloy Ti—6Al—4V, used for selective electron beam melting, are presented. The study reveals the structure and mechanical properties of standard thin samples made from the titanium alloy Ti—6Al—4V using the developed ‘thin walls’ mode. It has been established that the alloy structure obtained through the "thin walls" mode exhibits a Widmansttten structure with low dispersion of α-phase plates. The manufactured samples demonstrate higher strength compared to samples produced using traditional technology.
Improving Machine Reliability with Recurrent Neural Networks
Authors: Tito Ayyalasomayajula Madan Mohan , Ayyalasomayajula Sailaja
Published: September 2024

This study explores the application of recurrent neural networks (RNNs) to enhance machine reliability in industrial settings, specifically in predictive maintenance systems. Predictive maintenance uses previous sensor data to identify abnormalities and forecast machine breakdowns before they occur, lowering downtime and maintenance costs. RNNs are ideal with their unique capacity to handle sequential input while capturing temporal relationships. RNN-based models may reliably foresee machine breakdowns and detect early malfunction indicators, allowing for appropriate interventions. The paper investigates key RNN architectures, such as Long Short-Term Memory (LSTM) and Gated Recurrent Units (GRU), that have proven effective in addressing the limitations of traditional machine learning models, particularly in dealing with long-term dependencies and avoiding the vanishing gradient issue. LSTMs and GRUs are noted for their excellent performance in predictive maintenance, which requires precise failure predictions. However, obstacles persist, notably regarding data quality—sensor data is often noisy, missing, or inconsistent—and model interpretability since RNNs' "black-box" nature makes comprehending predictions challenging. Addressing these difficulties is critical for effective adoption in industrial settings. Future directions include integrating domain knowledge to improve model accuracy and creating hybrid models that combine RNNs with machine learning techniques, such as convolutional neural networks (CNNs) or support vector machines (SVMs), to improve predictive maintenance systems' robustness and scalability. These developments might considerably impact equipment dependability and operational efficiency in production.
Empowering India's Micro-Entrepreneurs: An Analytical Overview of the Highlights of the MUDRA Scheme
Authors: Kumar Sunil
Published: September 2024

MUDRA scheme was launched in 2015 under Pradhan Mantri MUDRA Yojana with the objectives of supporting micro unit entrepreneurship and financial inclusion in the micro units by providing collateral free loans to non-corporate / non-individual entities. This paper delves into the impact of the established scheme in relation to employment, financing, and business development with a special focus on women and vulnerable persons. However, the scheme has been effective in the goal of credit access and addendum comes with challenges like the increasing NPAs and the sustainability of employment generation. This research analyzes loan disbursements, non-performing assets and the financial sustainability of the program through quantitative and qualitative research methods. It provides policy recommendations to improve the effectiveness of the scheme. Greater emphasis on risk management, financial awareness, and the enhanced application of technology is necessary for the continued success and effectiveness of the MUDRA scheme as a model for the further development of the financial inclusion of the population in India. Some possibilities for further research are: focusing on particular industries and presenting the implementation differences at the regional level.
A IMPORTÂNCIA DA MICROBIOTA INTESTINAL E DO ALEITAMENTO MATERNO NO DESENVOLVIMENTO INFANTIL: UMA REVISÃO DE LITERATURA
Authors: Andrade de Osti Fernanda , Moroti Roncari Maria Eduarda , Bettoni Ana Letícia , Zieri Carminati Júlia , Zanqueta Maria Caroline , Silvério Gabriela , Drachewski Scofoni de Sousa Tayná , Farah Lauria Mantovani Beatriz
Published: September 2024

Introdução: A microbiota intestinal exerce uma grande mudança no processo de saúde infantil, destacando o leite materno como grande influência na microbiota. Assim, esse contém micróbios, metabólitos, imunoglobulinas e substâncias probiótica, prebiótico e pós-bióticas que são essenciais para o desenvolvimento saudável do sistema digestivo infantil, podendo impactar o desenvolvimento e acarretar consequências par ao indivíduo. Objetivo: O estudo visa correlacionar o aleitamento materno com a microbiota intestinal, destacando sua importância e impacto no desenvolvimento do bebê. Metodologia: Para essa revisão bibliográfica, foram utilizadas as bases de dados PubMed, Scielo e BVS, com as palavras-chave: “Leite humano”, “Microbiota intestinal”, “Gut Microbiota” e “Milk, Human”, tanto individualmente quanto em combinações baseado em artigos originais e de revisão nas línguas inglesa e portuguesa. No total, foram revisadas 35 publicações, das quais 16, datadas de 2015 a 2024, foram selecionadas para este estudo. Resultados: Os estudos analisados ressaltam a importância da microbiota intestinal e do aleitamento materno para o desenvolvimento infantil e a saúde a longo prazo. Entre os 16 artigos revisados, 4 destacaram a relação direta entre aleitamento materno e microbiota intestinal, enquanto 12 focaram importância da microbiota intestinal. Conclusão: A amamentação não apenas promove a saúde infantil a longo prazo, mas também contribui significativamente para a manutenção do bem-estar e qualidade de vida, através de sua oferta de prebióticos, probióticos e pós-bióticos essenciais para a microbiota intestinal.
EFFECTIVE PEDAGOGICAL STRATEGIES FOR DIGITAL LEARNERS
Authors: Junard P. Duterte
Published: September 2024

This study investigated the effectiveness of various pedagogical strategies in digital learning environments, focusing on blended learning, gamification, adaptive learning technologies, interactive multimedia content, and frequent feedback. Employing a mixed-methods approach, the research combined quantitative surveys and qualitative interviews with students and educators to assess the impact of these strategies on engagement, motivation, and academic performance. The results revealed that blended learning enhances flexibility and personalization, gamification increases motivation through interactive elements, and adaptive technologies tailor content to individual needs. Interactive multimedia content improves retention and understanding of complex concepts, while frequent feedback supports continuous learner development. The findings emphasized integrating diverse pedagogical strategies to optimize digital education and address varying learner needs. Future research should explore the long-term impacts of these strategies, emerging technologies, and their effectiveness across different educational contexts to ensure equitable and compelling learning experiences.
KEYWORDS: blended learning, gamification, adaptive learning technologies, multimedia content, frequent feedback, digital learning, educational technology
Indonesian Islamic Theology: Understanding Exclusivism, Inclusivism, and Pluralism in the Context of Religious Plurality
Authors: Rustriningsih Rustriningsih , Saad Mukhlisin
Published: September 2024

In Indonesia, religious issues have emerged as a subject of intense debate and polemic. Conflicting religious claims often incite debates and hostilities purportedly in the name of faith. In certain instances, the emergence of inter-religious conflicts in Indonesia is exacerbated by exclusionary perspectives on religion. This study aims to critically examine the concept of Islamic theology within the context of Indonesia’s pluralistic society, characterized by its rich religious diversity. Employing a qualitative research methodology with a descriptive-analytical approach, this research utilizes library research to gather a variety of thematic literature. The findings indicate that Indonesia is a nation marked by significant religious plurality. In this context, Islam, as an inherently open faith, embraces inclusivism and pluralism, which serve as essential frameworks for mitigating interfaith conflicts arising from competing religious truth claims. Consequently, the promotion of inclusivist and pluralist perspectives in religion fosters a culture of tolerance, thereby facilitating a harmonious coexistence among adherents of diverse faiths.
Pengaruh Profitabilitas, Likuiditas, Dan Ukuran Perusahaan Terhadap Manajemen Laba Pada Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia
Authors: Rachmalia Athira Mitha , Nursiam Nursiam
Published: September 2024

Menganalisis pengaruh profitabilitas, likuiditas, dan ukuran perusahaan terhadap manajemen laba adalah tujuan dari penelitian ini. Populasi yang digunakan dalam penelitian ini adalah Perusahaan Manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) selama periode 2020-2022. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Total keseluruhan sampel adalah 237 selama periode 2020-2022. Sampel yang diujikan tidak lolos sehingga harus dioutlier sebanyak 35 sampel, sehingga data penelitian yang diolah sebanyak 202 sampel. Pada penelitian ini menggunakan metode analisis regresi linier berganda dengan menggunakan SPSS versi 25. Hasil penelitian menunjukkan profitabilitas dan likuiditas berpengaruh terhadap manajemen laba, sedangkan ukuran perusahaan tidak berpengaruh terhadap manajemen laba pada perusahaan manufaktur yang terdaftar di bursa efek Indonesia 2020-2022.
Pengaruh Store Layout, Kualitas Pelayanan Dan Motivasi Rasional Terhadap Keputusan Pembelian Pada Toko Zam Zam Kota Bima
Authors: Gafiqi Abdul , Ismunandar Ismunandar , Mulyadin Mulyadin
Published: September 2024

Penelitian ini bertujuan untuk mengetahui pengaruh store layout, kualitas pelayanan dan motivasi rasional terhadap keputusan pembelian pada toko Zam-Zam Kota Bima.  Penelitian ini dilakukan di toko Zam-Zam Jl. Sultan Muhamad Salahuddin, Dara, Kec. Rasanae Barat Kota Bima. Dalam penelitian ini digunakan jenis penelitian asosiatif dengan menggunakan instrument penelitian kuesioner skala likert. Populasi dalam penelitian adalah semua masyarakat yang pernah membeli pada toko Zam-Zam kota Bima yang jumlahnya tidak diketahui pasti jumlahnya. Dikarenakan populasinya tidak diketahui secara pasti maka sampel penelitian sebanyak 96 orang dengan teknik penentuan sampel yaitu purposive sampling. Teknik pengumpulan data menggunakan observasi, kuesioner dan studi pustaka. Data yang telah dikumpulkan kemudian dianalisis dengan teknik uji validitas, uji reliabilitas, uji asumsi klasik, regresi linear berganda, koefisien korelasi berganda, uji determinasi, uji t dan uji f. Hasil penelitian menunjukan bahwa store layout berpengaruh terhadap keputusan pembelian pada toko Zam-Zam Kota Bima, sedangkan kualitas pelayanan dan motivasi rasional tidak berpengaruh terhadap keputusan pembelian pada toko Zam-Zam Kota Bima
Pengaruh Budaya, Sosial, Pribadi dan Psikologis Terhadap Keputusan Menabung di Perbankan Syariah ( Studi Pada Mahasiswa Prodi Ekonomi Syariah UIN STS Jambi)
Authors: Alfarisi M. Salman , Rafidah Rafidah , Budianto Achyat
Published: September 2024

Penelitian ini bertujuan untuk mengungkap pengaruh faktor budaya, sosial, pribadi dan psikologis terhadap keputusan menabung di perbankan syariah studi pada mahasiswa prodi ekonomi syariah UIN STS Jambi. Hasil penelitian menunjukkan bahwa faktor budaya (X1) memiliki pengaruh terhadap keputusan menabung di perbankan syariah pada mahasiswa prodi ekonomi syariah UIN STS Jambi secara parsial, hal ini dikarenakan dengan menabung di perbankan syariah mahasiswa menjalankan aturan sesuai dengan ajaran Islam, faktor sosial (X2) memiliki pengaruh terhadap keputusan menabung di perbankan syariah pada mahasiswa prodi ekonomi syariah UIN STS Jambi secara parsial, hal ini dikarenakan saja direkomendasikan dengan teman saya di lingkungan kampus, faktor pribadi (X3) memiliki pengaruh terhadap keputusan menabung di perbankan syariah pada mahasiswa prodi ekonomi syariah UIN STS Jambi secara parsial. Dikarenakan nilai F hitung (92.531) > F tabel (3,951) dan nilai signifikan (0.000) < a (0.05), disimpulkan Ho ditolak dan Ha diterima, artinya bahwa budaya, sosial, pribadi dan psikologis secara bersama-sama atau simultan berpengaruh terhadap keputusan menabung di perbankan syariah pada mahasiswa prodi ekonomi syariah UIN STS Jambi.
Pengaruh Audit Tenure dan Ukuran Perusahaan terhadap Audit Delay
Authors: Christofer Christofer , Haryono Haryono , Heniwati Elok
Published: September 2024

Tujuan penelitian ini adalah untuk menguji dan menganalisis pengaruh audit tenure dan ukuran perusahaan terhadap audit delay. Objek penelitian ini adalah perusahaan subsektor energi yang terdaftar di BEI periode 2020-2022. Teknik pengambilan sampel adalah purposive sampling, diperoleh 42 sampel. Metode penelitian adalah kuantitatif dengan teknik analisis regresi berganda menggunakan software Eviews 12. Variabel penelitian ini terdiri dari audit tenure, ukuran perusahaan, dan audit delay. Hasil penelitian ini menunjukkan bahwa audit tenure tidak berpengaruh terhadap audit delay, sedangkan ukuran perusahaan berpengaruh terhadap audit delay. Hasil penelitian ini menyiratkan bahwa semakin besar ukuran perusahaan, maka pelaporan keuangan menjadi lebih tepat waktu. Hal ini karena perusahaan besar biasanya memiliki sistem pengendalian manajemen yang lebih ketat, sehingga laporan keuangan harus diserahkan tepat waktu. Oleh karena itu, perusahaan kecil sebaiknya dikelola dengan sistem pengendalian manajemen yang baik untuk mencegah audit delay.
Kajian Harmonisasi dan Inovasi Kerja Dosen: Studi Kasus di Perguruan Tinggi Swasta di Kota Medan
Authors: Simamora Rusdiana Br , Irwadi Irwadi , Leonid Michelyn
Published: September 2024

Penelitian ini bertujuan untuk menganalisis peran harmonisasi dedikasi dalam memediasi pengaruh servant leadership, lack of management support, dan work overload terhadap inovasi kerja dosen di perguruan tinggi swasta di Kota Medan. Metode penelitian yang digunakan adalah pendekatan kuantitatif dengan model Structural Equation Model (SEM). Adapun target populasi dan sampel dalam penelitian ini yaitu 103 dosen di Sekolah Tinggi Ilmu Ekonomi (STIE) di Kota Medan, yang mencakup STIE IBMI, STIE Eka Prasetya, STIE Profesional Indonesia, STIE Pangeran Antasari, STMB Multi Smart, dan STIE Graha Kirana. Selanjutnya data dikumpulkan melalui kuesioner yang dirancang berdasarkan dimensi atau indikator dari setiap variabel penelitian. Hasil penelitian menunjukkan bahwa servant leadership secara langsung berpengaruh positif dan signifikan terhadap harmonisasi dedikasi. Lack of management support juga menunjukkan pengaruh positif dan signifikan terhadap harmonisasi dedikasi. Sebaliknya, work overload tidak berpengaruh signifikan terhadap harmonisasi dedikasi. Harmonisasi dedikasi terbukti berpengaruh positif dan signifikan terhadap inovasi kerja dosen. Selain itu, harmonisasi dedikasi memediasi pengaruh servant leadership  dan lack of management support terhadap inovasi kerja dosen. Namun, harmonisasi dedikasi tidak memediasi pengaruh work overload terhadap inovasi kerja dosen. Temuan ini mengindikasikan bahwa peningkatan servant leadership dan dukungan manajemen yang memadai berpotensi memperbaiki inovasi kerja dosen melalui harmonisasi dedikasi, sementara beban kerja yang berlebihan tidak berpengaruh signifikan pada inovasi kerja, dan harmonisasi dedikasi tidak berfungsi sebagai mediator dalam konteks ini. Penelitian ini memberikan wawasan penting bagi pengelola perguruan tinggi swasta dalam merancang strategi untuk meningkatkan inovasi kerja dosen melalui pengembangan kepemimpinan dan dukungan manajerial yang efektif
Pengaruh Kinerja Individu, Kualitas Pelayanan, dan Nilai Pelanggan Terhadap Manfaat Sistem Informasi Akuntansi Implikasi Supply Chain (Survey Pada Karyawan PT. Trans Musi Palembang Jaya)
Authors: Nurmaimuna Anggini , Romli Harsi , Tripermata Lukita
Published: September 2024

Penelitian ini bertujuan untuk menganalisis pengaruh kinerja individu dalam memahami dan menggunakan sistem informasi akuntansi terhadap kualitas pelayanan dan nilai yang dirasakan oleh pelanggan dan karyawan di PT. Trans Musi Palembang Jaya. Penelitian ini menggunakan teknik sample dengan cara sampling jenuh. Pengumpulan data menggunakan kuesioner. Berdasarkan hasil penelitian menunjukkan bahwa variabel kinerja individu tidak berpengaruh signifikan terhadap sistem informasi akuntansi dengan nilai 0,200 < 2,011 dengan signifikan 842 > 0,05. Kualitas pelayanan berpengaruh signifikan terhadap sistem informasi akuntansi dengan nilai 3,698 > 2,011 dengan signifikan 0,01 > 0,05 dan nilai pelanggan berpengaruh signifikan terhadap sistem informasi akuntansi dengan nilai 3,515 > 2,011 dengan signifikan 0,01, dan sistem informasi akuntansi berpengaruh signifikan terhadap supply chain dengan nilai 4,811 > 2,011 dengan signifikan 0,00 < 0,05. Berdasarkan hasil uji koefisien regresi berganda didapat persamaan 1 Y1= 10,902 + 0,046 X1+ 0,458 X2 + 0,623 X3 + e dan persamaan 2 Y2= 21,142 + 0,480 Y1. Berdasarkan temuan ini, PT. Trans Musi Palembang Jaya disarankan untuk meningkatkan program pelatihan dan pengembangan karyawan, terus meningkatkan kualitas pelayanan, mengoptimalkan penggunaan sistem informasi akuntansi, mengembangkan strategi pemasaran yang efektif, dan menjalin kemitraan dengan pihak ketiga untuk meningkatkan kualitas layanan dan infrastruktur. Dengan demikian, perusahaan dapat memberikan nilai yang lebih tinggi kepada pelanggan dan meningkatkan daya saing di industri transportasi
Pelatihan Membanyakan Herbisida Sendiri Untuk Pengurangan Biaya Produksi Petani
Authors: Girsang Warlinson , Girsang Rosmaria , Nainggolan Olivia J , Manihuruk Deana , Turnip Amsal Randy , Girsang Jondarta , Saragih Basriadi
Published: September 2024

Herbicides are needed by farmers to control weeds in their farming land. Although the price of herbicides is expensive, farmers always try to buy them. The need for working capital to buy herbicides is one of the factors that drives the increase in farm production costs. The initial survey of potential partner farmers illustrates that farmers are familiar with and have used various types of herbicides. However, all farmers in Dusun Bah Bulawan do not know how to make or reproduce herbicides. All farmers depend on buying commercial herbicides from agricultural kiosks, which are relatively expensive and tend to increase from year to year. Based on the situation analysis of partner farmers, a concept was formulated, namely how to make farmers' knowledge change from not knowing to knowing in terms of multiplying herbicides. The strategy of the activities carried out is to organize training. Farmers are equipped with technological knowledge to reproduce their own herbicides. With the skills of being able to reproduce their own herbicides, it is hoped that farmers can save production costs. Because the cost of buying herbicides can be reduced by a significant amount. The general objective of training activities is to help farmers overcome their problems and reduce farm production costs. Meanwhile, the specific objective is to increase the welfare of farmers through savings in farm production costs. Benefits of the activity: the knowledge and skills of farmers will increase, especially the technology for increasing herbicides. While the impact of activities: (a). Farmers gain additional knowledge of technology transfer from universities and create synergistic cooperation between universities and the community. (b). Farmers know more about the use of herbicides as weed control. (c). Farmers' knowledge changed from not knowing to knowledgeable in terms of multiplying herbicides. (d). Farmers are able to multiply their own herbicides to reduce farm production costs. (e). The level of income and welfare of farmers is expected to increase, because production costs for controlling weeds can be saved
Sosialisasi Pemahaman Tentang Sengketa Hak Milik Atas Tanah Kepada Masyarakat Di Kelurahan Sukamakmur Pematangsiantar
Authors: Christian Daniel Hermes  , Nainggolan Rosita , Sitinjak Humala , Sitinjak Imman Yusuf
Published: September 2024

Fenomena sengketa hak milik sangat besar di masyarakat khususnya di Kelurahan Sukamakmur Kecamatan Siantar Marihat Kota Pematangsiantar. Peran Dosen Fakultas Hukum sangat di perlukan untuk  memberikan pengetahuan hukum terkait dengan sengketa hak milik atas tanah. Metode yang dilakukan dalam pengabdian ini adalah metode diskusi serta pendampingan hukum bagian keperdataan dengan masyarakat langsung. Hasil yang dicapai dalam program PKM ini adalah peningkatan kesadaran masyarakat Kelurahan Sukamakmur dalam memahami sengketa hak milik atas tanah melalui peran Lembaga Bantuan Hukum Universitas Simalungun dengan cara penyuluhan  hukum dengan  mekanisme ceramah, diskusi. Meteri ceramah dan diskusi. Disamping itu kegiatan ini dilakukan agar masyarakat memahami dan mengetahui pentingnya kesadaran hukum. Metode yang digunakan dalam pencapaian tujuan tersebut adalah pemberdayaan masyarakat melalui sosialisasi. Metode ini  digunakan dalam melakukan pemberdayaan kelompok sasaran seperti kelompok masyarakat, pemuda, dan pemerintah Kelurahan
Pendampingan Pengelolaan Desa Wisata Nagori Tigaras
Authors: Munthe Risma N , Napitu Resna , Purba Desmi , Simbolon Pirma , Simatupang Pandapotan , Sinaga Mahaitin H
Published: September 2024

Kegiatan pengabdian pada masyarakat ini adalah Pendampingan Pengelolaan Desa Wisata Nagori Tigaras. Pengabdian ini bertujuan untuk mendampingi masyarakat Nagori Tigaras dalam menjalankan bisnis Desa Wisata. Khalayak sasaran dalam kegiatan ini adalah masyarakat Nagori Tigaras berjumlah 15 orang. Pendampingan kegiatan ini dilakukan  dengan cara ceramah bervariasi dan evaluasi. Metode ceramah digunakan untuk menjelaskan konsep bisnis, macam media, kelebihan dan kekurangan penggunaan media dalam bisnis wisata, keramahtamahan 3S (Senyum, Salam, Sapa), pemberdayaan masyarakat setempat untuk bisnis Homestay dan langkah-langkah pengelolaan bisnis usaha Desa Wisata. Pelaksanaan kegiatan ini didukung oleh antusias peserta, pangulu dan dana kegiatan. Adapun kendala yang dihadapi adalah para peserta adalah berfikir bahwa bisnis yang sedang dijalankan sudah baik/ berda pada zona nyaman; Tidak mau pusing; Bingung cara memulai mengembangkan usahanya; Tidak melihat adanya potensi lain yang dapat dikelola dan dikembangkan; Tidak memiliki dukungan; Tidak ada mentor dalam bisnis. Manfaat yang dapat diperoleh peserta dari kegiatan pengabdian ini antara lain dapat meningkatkan jumlah pengunjung wisatawan
COMPARATIVE ANALYSIS OF ANTI-CORRUPTION LEGISLATION OF UKRAINE AND EU COUNTRIES: IMPLEMENTATION AND ADAPTATION OF BEST PRACTICES
Authors:   Institute of Law and Public Relations, Open International University of Human Development ", Komarov Maksym ,   Ukraine",   , Kyiv, Ukraine
Published: September 2024

The article provides a comparative analysis of the anti-corruption legislation of Ukraine and thecountries of the European Union in order to determine the best practices and the possibilities of their implementation in the Ukrainian legal system. The main anti-corruption mechanisms, including legislation, institutional structure and practical measures appliedin Poland, Romania and Germany, are considered. The main provisions of the Ukrainian anti-corruption legislation are analyzed, in particular the role and functions of the National Anti-Corruption Bureau of Ukraine (NABU), the National Agency for the Prevention of Corruption (NACP) and the Supreme Anti-Corruption Court (SAC). The main achievements and problems in the functioning of anti-corruption bodies in Ukraine have been identified. Special attention is paid to the comparison of the institutional structure, transparency and accountability of anti-corruption mechanisms, as well as the legislative framework of Ukraine and EU countries. The key challenges and prospects for the implementation of European practices in Ukraine are identified, including issues of political will, institutional capacity, and public support. Based on the analysis, recommendations were developed for improving Ukrainian anti-corruption legislation, strengthening the independence of anti-corruption bodies, and involving civil society in the fight against corruption. The article also contains suggestions for further research in this area.
THE DEVELOPMENT OF PUBLIC-PRIVATE PARTNERSHIP FOR UKRAINE BASED ON GLOBAL PRACTICE EXPERIENCE
Authors:   Institute of Law and Public Relations, Open International University of Human Development ", Dabizha Vira ,   Ukraine",   , Kyiv, Ukraine, Samkov Oleksandr ,   Institute of Law and Public Relations, Open International University of Human Development "Ukraine", Kyiv, Ukraine
Published: September 2024

Public-Private Partnership (PPP) is a strategic collaboration between the public and private sectors aimed at jointly addressing socio-economic challenges and achieving specific goals. This type of partnership is becoming increasingly relevant in today's world, where complex social, economic, and environmental challenges require a comprehensive approach to their resolution.PPP can encompass a wide range of areas, including infrastructure, healthcare, education, energy, technology, and many others. It is based on principles of mutual assistance, trust, risk sharing, and responsibility between government and private entities. At the international level, PPP plays a key role in jointly addressing global issues such as climate change, population growth, military conflicts, and poverty. International PPPs serve as a mechanism for leveraging resources and expertise from different countries and international organizations.Such partnerships facilitate more efficient use of resources, exchange of best practices and technologies, and contribute to strengthening international cooperation and understanding among nations. In practice, the partnership between the government and the private sector is focused on attracting investments for financing. Mutual economic interest arises when their strategic goals and tasks intersect. Government structures, along with businesses, aim to achieve global objectives through the application of commercial opportunities and focusing on enterprises to implement economic and social approaches, expand the economic sphere, and develop cooperation in the field of progressive solutions. Private enterprises, through joint cooperation with government authorities, aim to achieve their goals for development and protection of their interests. Ukraine is also actively developing PPP as a tool to improve management efficiency, attract investments, and implement strategic projects. Public-private partnership opens up new opportunities for infrastructure development, enhancing the competitiveness of the economy, and ensuring sustainable socio-economic growth.
Pemanfaatan Limbah Padat Penyulingan Daun Cengkeh Menjadi Biobriket Di Desa Kalipucang
Authors:   UniversitasPembangunan Nasional Veteran Jawa Timur, Af'ida Layyinatul , Sani Sani ,   UniversitasPembangunan Nasional Veteran Jawa Timur, Siswati Nana Dyah ,   UniversitasPembangunan Nasional Veteran Jawa Timur
Published: September 2024

Daun cengkeh kering dari hasil penyulingan minyak atsiri daun cengkeh seringkali dipandang sebagai limbah industri yang pemanfaatannya masih kurang. Limbah daun cengkeh ini biasanya hanya digunakan sebagai bahan bakar tambahan untuk proses penyulingan di Desa Kalipucang. Sehingga limbah tersebut dapat dimanfaatkan untuk diolah menjadi biobriket dengan campuran arang sekam padi. Biobriket adalah sumber energi alternatif yang terbuat dari campuran biomassa dengan proses karbonisasi bersuhu tinggi. Tujuan dari pemanfaatan limbah daun cengkeh yaitu untuk mengurangi limbah yang terbuang dan menjadikannya produk yang memiliki nilai jual bagi masyarakat Desa Kalipucang. Metode pelaksanaan yang dilakukan yaitu pembuatan biobriket daun cengkeh dan penyuluhan kepada masyarakat. Hasil capaian kegiatan ini adalah briket daun cengkeh yang ramah lingkungan. Pembuatan biobriket daun cengkeh ini diharapkan mampu menjadi solusi alternatif terhadap limbah penyulingan daun cengkeh di Desa Kalipucang.
Strategi Promosi atau Membangun Brand Image pada Media Digital/Online pada UMKM Fashion @Highlaff.id2
Authors:   Universitas Internasional Batam, Astuty Dessy , Yuswardi Yuswardi ,   Universitas Internasional Batam
Published: September 2024

Laporan ini membahas peran dan strategi pemasaran online shop dengan fokus pada Highlaff.id, sebuah platform penjualan daring. Dengan masyarakat semakin tertarik pada online shop, faktor-faktor seperti harga ekonomis, pengiriman gratis, dan pengalaman berbelanja yang nyaman menjadi pendorong utama. Media sosial seperti Instagram dan TikTok menjadi sarana utama bagi pelaku bisnis daring untuk melakukan promosi dan penjualan secara efisien.Penelitian ini menerapkan Teori Integrated Marketing Communication (IMC) dalam strategi penjualan online shop, menggabungkan elemen periklanan, promosi penjualan, hubungan masyarakat, pemasaran langsung dan digital, serta identitas merek. Dalam era digital, IMC menjadi landasan esensial, memanfaatkan data dan analitik untuk membangun keterlibatan konsumen dan citra merek positif melalui interaksi langsung dengan konsumen di platform sosial media. Selanjutnya, laporan ini menyoroti tantangan yang dihadapi oleh online shop Highlaff.id2, terutama terkait omset pendapatan yang kurang stabil dan ketidakmengenalannya di kalangan masyarakat. Dalam rangka membantu pemilik usaha mengatasi masalah ini, penelitian ini memaparkan implementasi strategi digital marketing, terutama melalui video promotion dan advertising di TikTok dan Instagram. Pengumpulan data dilakukan melalui wawancara dengan pemilik usaha, pelanggan, dan manajemen operasional Highlaff.id2.Hasil implementasi menunjukkan adanya peningkatan respons positif dan pengikut di media sosial, memberikan dorongan positif terhadap penjualan online shop Highlaff.id2. Penelitian ini berusaha memberikan gambaran komprehensif tentang bagaimana penerapan IMC dan strategi digital marketing dapat meningkatkan kinerja dan keberhasilan online shop, dengan fokus pada studi kasus Highlaff.id2 di tengah persaingan yang ketat di pasar e-commerce.
A Prospective Study on the Assessment of Complications in Pregnancy at an Indian Super Specialty Hospital
Authors: S Ramachandran , Sripada Ramam , Azra Shams Hussaini Azra , Raj Sali Swarna , Maiga Haoua , K Aruna Kumari , Magharla Dasaratha Dhanaraju
Published: September 2024

The main of this study is to estimate the prevalence of complications in pregnancy at an Indian superspeciality hospital. We considered all age groups of pregnant with more than 12 weeks of gestational age as inclusion criteria whereas the pregnant with other co-morbid conditions were considered as exclusion criteria with a prospective way of approach. Among the 325 pregnant, 74 (22.7%) were observed with complications during their pregnancy. Most of the pregnant women with complications were observed in the 26-30 years age group (43.2%) and the majority were observed with the complication hypothyroidism (71.6%) followed by gestational diabetes (13.5%). Most of the pregnant women were observed with complications in the first trimester (78.4%) followed by the second trimester (20.3%). Clinical pharmacists along with obstetricians should create awareness regarding the complications during pregnancy in order to prevent them in the early stage. Counselling sessions during the different trimesters will definitely show a positive impact in maintaining the overall health of pregnant women.
Stability-Indicating HPLC Method for Quantifying Process-Related Impurities in Fedratinib and Identification of Its Forced Degradation Products Using LC-MS/MS
Authors: Panchadi Gowtham , Uppu Naga Babu , Tatavarti Bhagya Kumar , V.B.V.N. Prasad , Anna Venkateswara Rao
Published: September 2024

Background: Pharmaceutical industry is characterized by rigorous quality standards to ensure the safety and efficacy of drugs. Despite stringent manufacturing processes, the presence of impurities or generation of degradation products (DPs) in pharmaceutical products remains a concern. This necessitates a comprehensive and systematic approach to analysis impurities and DPs.
Objectives: This study deals with the optimization of the stable HPLC method for quantification of fedratinib impurities and its DPs characterization through LC-MS/MS. 
Method: Method optimization studies were conducted by analyzing standard solutions in various method parameters. The results noticed in every varied method condition were tabulated for finalizing the appropriate conditions for analyzing fedratinib. The mass spectral response of DPs was interpreted carefully for structural conformation of DPs. 
Results: The method is optimized as HIQSIL C18 (250mm×4.6mm;5µ) column employing 1.0 mL/min flow of phosphate buffer (pH 5.2) and acetonitrile in 45:65 (v/v) and 257 nm. This method elutes 5.4, 2.6, 9.2 and 3.5 min for fedratinib, impurity 1, 2 and 3 respectively. Method sensitivity was verified to be very sensitive that can evaluate up to 0.003, 0.015 and 0.004 µg/mL for impurity 1, 2 and 3 respectively. Well correlated calibration curve achieved in 50-200 µg/mL for fedratinib and 0.05-0.20 µg/mL for impurities. Various stress studies produce four stress DPs and were identified using LC-MS/MS. The molecular mass (g/mol) and formula of DPs were identified as 426 and C21H25N5O3S, 312 and C17H22N5O, 354 and C17H14N4O3S, 215 and C11H11N4O respectively for DP 1 to 4. 
Conclusion: The method proposed can successfully be helpful for quantifying the pharmaceutical impurities and DPs of fedratinib in bulk batch samples and formulations.
Evaluation of Beta-cell Regeneration Property of Methanolic Extract of Momordica Dioica in Wistar Rat Model
Authors: Neve Vrushali Neve , Tonape Ashwini , Bhalchim Vrushali , Karwa Pawan , Panbhare Kartik
Published: September 2024

Background: Despite the existence of various medications for diabetes, many individuals still struggle with the condition due to the potential side effects associated with current treatments. Traditional healers have long relied on medicinal plants with potential antidiabetic properties. One such plant is Momordica dioica, although its traditional use lacks experimental studies to support its efficacy in managing diabetes. Among them, Momordica dioica is one however there are no experimental studies on beta-cell regeneration that support the current traditional uses. 
Objective: The main aim of the current research is to identify Momordica dioica's methanolic extract's capacity for beta cell regeneration.
Methods: Air-dried Fruit of Momordica Dioica was extracted using methanol, and acute oral toxicity studies were performed on methanolic extract in accordance with OECD guideline version 18. By using the HPTLC method, the Active Constituent in charge of the activity was verified. The HPTLC method was used to confirm active constituents that were responsible for the activity. The pancreatic beta cell regeneration as well as Fasting blood glucose level was used to evaluate the anti-diabetic effect. Single-dose STZ-induced type 2 diabetes mellitus was used to evaluate anti-antidiabetic activity.
Results: Momordica dioica’s methanolic extract with doses of 100mg/kg and rest combination with standard showed a significant (p < 0.0001) anti-diabetic effect.  Maximum anti-diabetic effects at doses as HE100mg/kg and all combinations were compared to standard and observed from Day 21 induction of diabetes by Streptozotocin; total tested doses of the extract inhibited the destruction of beta-cell significantly (p < 0.0001, p < 0.001). 
Conclusion: The existence of berberine, a quaternary ammonium salt of the alkaloid benzyl-iso-quinoline present in the extract, had a potential anti-diabetic effect and beta-cell regeneration property which supports the ancient beliefs.
Edukasi Pajak Pada Usaha Angkringan dan Warkop di Kecamatan Cikarang Pusat
Authors: Tikaromah Oom , Yuningsih Nining , Prasetyo Bayu , Sahirah Anisa Maulidatus , Ardiyan Ardiyan
Published: September 2024

Cikarang Pusat sub-district is one of the areas with economic growth driven by the presence of small and medium enterprises, including Angkringan and Warkop businesses. However, business actors' understanding of tax obligations is still shallow. This activity aims to provide tax education to partners to increase their tax awareness and compliance. The method used includes an initial survey to identify the level of understanding and educational needs, and implementation is carried out through direct assistance in the field. The results of the activity showed a significant increase in business owners' awareness and understanding of taxation knowledge after participating in the education programme. Before the programme, partners had an average knowledge of 45% regarding taxation, while after the programme, this figure increased to 85%. Continued education and support from the government and related organisations are needed to ensure the sustainability and positive impact of this programme.
Meningkatkan Penjualan UMKM sebagai Wujud Pemberdayaan Pada UMKM Bangun Jaya Di Desa Sukaraya
Authors: Ismamudi Ismamudi , Dharma Yuki Dwi
Published: September 2024

Abstract
The Micro, Small, and Medium Enterprises (MSME) sector plays a crucial role in shaping Indonesia's economic activity and serves as a fundamental pillar of the national economy. According to Law No. 20 of 2008, MSMEs refer to productive enterprises that are owned by people or corporate entities and fulfill certain conditions. The objective of this study is to investigate the Bangun Jaya banana bread micro, small, and medium enterprise (MSME) in Hamlet 1 Sukaraya Village, which is overseen by Pak Nedi. The study employs qualitative methodologies to comprehensively comprehend the operations of these micro, small, and medium enterprises (MSMEs). Comprehensive interviews, observation, and documentation acquired the data. The study findings indicate that Bangun Jaya's banana bread manufacturing system is commendable and sophisticated. However, there are still challenges in terms of marketing. The involvement of the Real Work Lecture team from Pelita Bangsa University enables the implementation of a more comprehensive marketing approach to boost sales of this product.
Nilai Spiritualitas dalam Seni Kaligrafi Ayat Kursi
Authors: Ady Khilmi , Mustofa Ahmad , Nadlir Muhammad Abu
Published: September 2024

The problem addressed in this study originates from the phenomenon of numerous calligraphers offering products featuring calligraphy of Qur'anic verses, with Ayat Kursi being the most popular among the public. This research area is known as Living Qur'an, which focuses more on the practical role of the Qur'an. In this case, the Qur'an is not only a guide but also used as home decoration in the form of calligraphy. This study employs a qualitative research method with Alfred Schutz's phenomenological approach, specifically in-order-to motive and because motive, to uncover the reasons and purposes behind the installation of Ayat Kursi calligraphy. The research data is collected from observations, interviews, and documentation. This study finds that the people of Magelang Regency have a strong preference for Ayat Kursi calligraphy because it is believed to bring blessings, reflect Islamic identity, and possess the power of prayer. The installation of Ayat Kursi calligraphy in homes serves not only as aesthetic decoration but also as a reminder of Allah's greatness, a source of spiritual protection, and a medium for creating a peaceful atmosphere.