bluuebunny/crossref_metadata_2025 huggingface dataset:
ADHD and associated psychopathology in older adults in a German community sample
Authors: Müller Marcus , Turner Daniel , Barra Steffen , Rösler Michael , Retz Wolfgang
Published: January 2023

Attention deficit hyperactivity disorder (ADHD) is still a neglected disorder in older adults. The aim of the present study was to examine the prevalence and symptomatology of ADHD and associated psychopathology in adults aged 40–80 years in a German community sample. We examined 539 participants in two age groups: (1) 40–59 years old (n = 256) and (2) 60–80 years old (n = 283). To assess ADHD in both childhood and adulthood as well as current psychopathological impairments, we used self-report instruments and corresponding observer reports. We examined group differences between age groups and between ADHD and non-ADHD groups. The prevalence of ADHD in the total sample was 2.6% with no significant differences between the two age groups (40–59 years: 3.1% vs. 60–80 years: 2.1%). Although differences emerged in impulsivity/emotional lability and self-concept problems, overall ADHD symptom ratings did not differ between the age groups. The ADHD group showed more psychopathological peculiarities compared to individuals without ADHD with medium-to-large effect sizes. Self-reports and observer reports showed good concordance in the assessment of ADHD and comorbid psychopathological symptoms. Regarding current ADHD symptomatology, in 92.1%, self-report was corroborated by observer's information. Our findings underline that ADHD symptoms are relevant across the lifespan. Augmenting self-reports with observer reports could increase the assessment quality of ADHD. For successful treatment, clinicians should also focus on additional psychopathological impairments and comorbidities in older adults with ADHD.
Driving time drives the hospital choice: choice models for pelvic organ prolapse surgery in Italy
Authors: Ferrari Amerigo , Seghieri Chiara , Giannini Andrea , Mannella Paolo , Simoncini Tommaso , Vainieri Milena
Published: January 2023

Objective

The Italian healthcare jurisdiction promotes patient mobility, which is a major determinant of practice variation, thus being related to the equity of access to health services. We aimed to explore how travel times, waiting times, and other efficiency- and quality-related hospital attributes influenced the hospital choice of women needing pelvic organ prolapse (POP) surgery in Tuscany, Italy.

Methods

We obtained the study population from Hospital Discharge Records. We duplicated individual observations (n = 2533) for the number of Tuscan hospitals that provided more than 30 POP interventions from 2017 to 2019 (n = 22) and merged them with the hospitals’ list. We generated the dichotomous variable “hospital choice” assuming the value one when hospitals where patients underwent surgery coincided with one of the 22 hospitals. We performed mixed logit models to explore between-hospital patient choice, gradually adding the women’s features as interactions.

Results

Patient choice was influenced by travel more than waiting times. A general preference for hospitals delivering higher volumes of interventions emerged. Interaction analyses showed that poorly educated women were less likely to choose distant hospitals and hospitals providing greater volumes of interventions compared to their counterpart. Women with multiple comorbidities more frequently chose hospitals with shorter average length of stay.

Conclusion

Travel times were the main determinants of hospital choice. Other quality- and efficiency-related hospital attributes influenced hospital choice as well. However, the effect depended on the socioeconomic and clinical background of women. Managers and policymakers should consider these findings to understand how women behave in choosing providers and thus mitigate equity gaps.
Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models
Authors: Jafarinia Alireza , Melito Gian Marco , Müller Thomas Stephan , Rolf-Pissarczyk Malte , Holzapfel Gerhard A. , Brenn Günter , Ellermann Katrin , Hochrainer Thomas
Published: January 2023

Type B aortic dissection (TBAD) carries a high risk of complications, particularly with a partially thrombosed or patent false lumen (FL). Therefore, uncovering the risk factors leading to FL thrombosis is crucial to identify high-risk patients. Although studies have shown that morphological parameters of the dissected aorta are related to FL thrombosis, often conflicting results have been reported. We show that recent models of thrombus evolution in combination with sensitivity analysis methods can provide valuable insights into how combinations of morphological parameters affect the prospect of FL thrombosis. Based on clinical data, an idealized geometry of a TBAD is generated and parameterized. After implementing the thrombus model in computational fluid dynamics simulations, a global sensitivity analysis for selected morphological parameters is performed. We then introduce dimensionless morphological parameters to scale the results to individual patients. The sensitivity analysis demonstrates that the most sensitive parameters influencing FL thrombosis are the FL diameter and the size and location of intimal tears. A higher risk of partial thrombosis is observed when the FL diameter is larger than the true lumen diameter. Reducing the ratio of the distal to proximal tear size increases the risk of FL patency. In summary, these parameters play a dominant role in classifying morphologies into patent, partially thrombosed, and fully thrombosed FL. In this study, we point out the predictive role of morphological parameters for FL thrombosis in TBAD and show that the results are in good agreement with available clinical studies.
Twenty-first century political justice: Reflections on the blind spots of current debates on penality
Authors: Brandariz José A.
Published: January 2023

This paper aims to examine the contours of current manifestations of political justice, in a time in which liberal democracy arrangements are more widespread than ever before. For these purposes, it begins by exploring international indices unveiling varying degrees of illiberal penal practices in global north jurisdictions. Subsequently, it scrutinises the Spanish penal field, in which outmoded political justice practices are intriguingly enduring and have been apparently on the rise over the last decade. In analysing the political catalysts of these Spanish cases, the paper sheds light on certain factors nurturing twenty-first century forms of political justice and enemy penology. Finally, the paper concludes by outlining a research agenda for seriously considering these ‘abnormal justice’ phenomena in current academic conversations on penality.
Taking a closer look at the regionally clustered firms: How can ambidexterity explain the link between management, entrepreneurship, and innovation in a post-industrialized world?
Authors: Mendes Telma , Braga Vítor , Silva Carina , Ratten Vanessa
Published: January 2023

The extant literature shows that innovation emerges from an interorganizational process, where a division of labor (both exploitation and exploration related) occurs among the actors within the cluster. Clustered firms are ambidextrous when they balance innovative activities that exploit existing competencies and are open to new technological approaches through exploration. In this context, we are interested in the role of clusters as supportive structures creating an atmosphere that encourages the development of interorganizational relationships, which assume a key relevance in explaining the ambidexterity and innovation of firms within the cluster. The question is whether there is an ideal combination to compete today (exploitation) while preparing to compete tomorrow (exploration), and if the networks developed in an industrial cluster play a role on determining innovative performance. Therefore, this study contributes to deepen the knowledge about the role of ambidexterity and network clustering on innovation. Specifically, by presenting a framework that explores the influence of external stakeholders and other clustered agents in the response of ambidextrous organizations to the challenges raised by environmental changes, we extend our discussion to a higher level of abstraction showing how ambidexterity can be the “black box” that connects the entrepreneurship, management, and innovation fields. The analysis of 1467 Portuguese firms suggests that network clustering has a direct positive impact on innovative performance, but also an indirect, mediated effect through exploration. Additionally, we found that a combination of exploitation and exploration (i.e., combined ambidexterity), and the trade-off between the two dimensions (i.e., imbalanced ambidexterity), leads to better innovation in agglomeration contexts. Our results, therefore, provide evidence that ambidexterity is the key to manage innovation strategic entrepreneurship’s tensions but, the way in which they are managed, is contingent on the clustered firms’ ability or inability to simultaneously pursue both exploitation and exploration.
Adult Kerion Celsi Caused by Trichophyton tonsurans Secondary to Black Dot Tinea Capitis
Authors: Ye Qian-ru , Luo Yu-wu , Zhou Xin , Li Qing-qing , Liu Yu-mei
Published: January 2023

A 34-year-old female patient presented with hair loss due to black dot tinea capitis
caused by Trichophyton tonsurans for 6 months. Hair loss progressed to painful
swelling for 2 months due to kerion Celsi which may be associated with treatment like
topical minoxidil, antibiotic and corticosteroid previously. The patient was treated with
oral Itraconazole initially without success but cured by Terbinafine eventually. It’s very
interesting that the patient caught kerion celsi secondary to a four-month history of hair
loss due to black dot tinea capitis.
Partisanship on Social Media: In-Party Love Among American Politicians, Greater Engagement with Out-Party Hate Among Ordinary Users
Authors: Yu Xudong , Wojcieszak Magdalena , Casas Andreu
Published: January 2023

Americans view their in-party members positively and out-party members negatively. It remains unclear, however, whether in-party affinity (i.e., positive partisanship) or out-party animosity (i.e., negative partisanship) more strongly influences political attitudes and behaviors. Unlike past work, which relies on survey self-reports or experimental designs among ordinary citizens, this pre-registered project examines actual social media expressions of an exhaustive list of American politicians as well as citizens’ engagement with these posts. Relying on 1,195,844 tweets sent by 564 political elites (i.e., members of US House and Senate, Presidential and Vice-Presidential nominees from 2000 to 2020, and members of the Trump Cabinet) and machine learning to reliably classify the tone of the tweets, we show that elite expressions online are driven by positive partisanship more than negative partisanship. Although politicians post many tweets negative toward the out-party, they post more tweets positive toward their in-party. However, more ideologically extreme politicians and those in the opposition (i.e., the Democrats) are more negative toward the out-party than those ideologically moderate and whose party is in power. Furthermore, examining how Twitter users react to these posts, we find that negative partisanship plays a greater role in online engagement: users are more likely to like and share politicians’ tweets negative toward the out-party than tweets positive toward the in-party. This project has important theoretical and democratic implications, and extends the use of trace data and computational methods in political behavior.
First Dirichlet Eigenvalue and Exit Time Moment Spectra Comparisons
Authors: Palmer Vicente , Sarrión-Pedralva Erik
Published: January 2023

We prove explicit upper and lower bounds for the Poisson hierarchy, the averaged L1-moment spectra $\left \{\frac {\mathcal {A}_{k}\left ({B_{R}^{M}}\right )}{\text {vol}\left ({S_{R}^{M}}\right )}\right \}_{k=1}^{\infty }$

A

k

B

R

M

vol

S

R

M

k
=
1

∞

, and the torsional rigidity $\mathcal {A}_{1}({B^{M}_{R}})$

A

1

(

B

R

M

)
of a geodesic ball ${B^{M}_{R}}$

B

R

M

in a Riemannian manifold Mn which satisfies that the mean curvatures of the geodesic spheres ${S^{M}_{r}}$

S

r

M

included in it, (up to the boundary ${S^{M}_{R}}$

S

R

M

), are controlled by the radial mean curvature of the geodesic spheres $S^{\omega }_{r}(o_{\omega })$

S

r

ω

(

o

ω

)
with same radius centered at the center oω of a rotationally symmetric model space $M^{n}_{\omega }$

M

ω

n

. As a consecuence, we prove a first Dirichlet eigenvalue $\lambda _{1}({B^{M}_{R}})$

λ

1

(

B

R

M

)
comparison theorem and show that equality with the bound $\lambda _{1}(B^{\omega }_{R}(o_{\omega }))$

λ

1

(

B

R

ω

(

o

ω

)
)
, (where $B^{\omega }_{r}(o_{\omega })$

B

r

ω

(

o

ω

)
is the geodesic r-ball in $M^{n}_{\omega }$

M

ω

n

), characterizes the L1-moment spectrum $\left \{\mathcal {A}_{k}({B^{M}_{R}})\right \}_{k=1}^{\infty }$

A

k

(

B

R

M

)

k
=
1

∞

as the sequence $\left \{\mathcal {A}_{k}(B^{\omega }_{R})\right \}_{k=1}^{\infty }$

A

k

(

B

R

ω

)

k
=
1

∞

and vice-versa.
Reference values of EORTC QLQ-C30, EORTC QLQ-BR23, and EQ-5D-5L for women with non-metastatic breast cancer at diagnosis and 2 years after
Authors: Miret Carme , Orive Miren , Sala Maria , García-Gutiérrez Susana , Sarasqueta Cristina , Legarreta Maria Jose , Redondo Maximino , Rivero Amado , Castells Xavier , Quintana José M. , Garin Olatz , Ferrer Montse ,   the REDISSEC-CaMISS Group, Comas Mercè , Domingo Laia , Macià Francesc , Roman Marta , Romero Anabel , Barata Teresa , Diez de la Lastra Isabel , de la Vega Mariola , Bare Marisa , Torà Núria , Ferrer Joana , Castanyer Francesc , Carmona Carmen , García Susana , Martín Maximina , Gonzalez Nerea , Valverde Maria Amparo , Saez Alberto , Barredo Inma , de Toro Manuel , Ferreiro Josefa , Pérez Jeanette , Valcárcel Cristina , Padilla María del Carmen , Téllez Teresa , Zarcos Irene , Churruca Cristina , Perales Amaia , Recio Javier , Ruiz Irune , Urraca Jose María , Michelena MªJesús , Moreno Julio , Mallabiabarrena Gaizka , Cobos Patricia , Otero Borja , Gorostiaga Javier , Troya Itsaso
Published: January 2023

Purpose

To obtain reference norms of EORTC QLQ-C30, EORTC QLQ-BR23, and EQ-5D-5L, based on a population of Spanish non-metastatic breast cancer patients at diagnosis and 2 years after, according to relevant demographic and clinical characteristics.

Methods

Multicentric prospective cohort study including consecutive women aged ≥ 18 years with a diagnosis of incident non-metastatic breast cancer from April 2013 to May 2015. Health-related quality of life (HRQoL) questionnaires were administered between diagnosis and beginning the therapy, and 2 years after. HRQoL differences according to age, comorbidity and stage were tested with ANOVA or Chi Square test and multivariate linear regression models.

Results

1276 patients were included, with a mean age of 58 years. Multivariate models of EORTC QLQ-C30 summary score and EQ-5D-5L index at diagnosis and at 2-year follow-up show the independent association of comorbidity and tumor stage with HRQoL. The standardized multivariate regression coefficient of EORTC QLQ-C30 summary score was lower (poorer HRQoL) for women with stage II and III than for those with stage 0 at diagnosis (− 0.11 and − 0.07, p < 0.05) and follow-up (− 0.15 and − 0.10, p < 0.01). The EQ-5D-5L index indicated poorer HRQoL for women with Charlson comorbidity index ≥ 2 than comorbidity 0 both at diagnosis (− 0.13, p < 0.001) and follow-up (− 0.18, p < 0.001). Therefore, we provided the reference norms at diagnosis and at the 2-year follow-up, stratified by age, comorbidity index, and tumor stage.

Conclusion

These HRQoL reference norms can be useful to interpret the scores of women with non-metastatic breast cancer, comparing them with country-specific reference values for this population.
Does geography matter? Implications for future tourism research in light of COVID-19
Authors: Sulyok Judit , Fehérvölgyi Beáta , Csizmadia Tibor , Katona Attila I. , Kosztyán Zsolt T.
Published: January 2023

Due to the 2019 new coronavirus disease (COVID-19) pandemic, tourism is undergoing fundamental changes that are affecting tourism research. This situation calls for in-depth analyses of tourism research. Scholars have already published review studies on COVID-19-related research within the tourism field; however, these studies do not connect findings, such as the research focus, research methodology and target group, to form a research profile, and the geographical patterns of the findings are not identified. study, COVID-19-related tourism studies were collected and analyzed in depth following the Preferred Reporting Items for systematic reviews and meta-analyses (PRISMA) method. In addition, data-driven methods, such as spatial multilayer networks, frequent patterns and content-based analyses, were applied to identify research profiles and their geographic patterns. This study pointed out the role of geographic patterns in tourism research, going beyond the research of the authors. Moreover, topics, focus destinations, applied methodologies and employed data sources have relevant geographic patterns. Four dominant research profiles that show that a shift can be observed in tourism research toward data sources and research methods were identified. Due to COVID-19, the strengthening of the application of quantitative methods and employment of secondary data sources are needed.
Renouncing the attempt versus perpetration distinction
Authors: Skoczeń Izabela
Published: January 2023

Legal and moral luck goes against the basic principle of criminal law that responsibility ascriptions are based on the mental state of the perpetrator, rather than merely the outcome of her action. If outcome should not play a decisive role in responsibility ascriptions, the attempt versus perpetration distinction becomes more difficult to justify. One potential justification is that we never know whether the attempter would not have resigned from pursuing her criminal intent even at the last moment. However, this paper argues that resigning from criminal intent and trying to stop the criminal outcome, which is called the renunciation defense, can be just as subject to outcome luck as the attempt versus perpetration distinction. And yet the availability of the renunciation defense in court is outcome dependent. I show with a series of experiments (N = 479) that outcome dependence for the renunciation defense is perceived as unjust and discuss the implications for the renunciation defense as well as attempt versus perpetration distinction.
Nudging for changing selves
Authors: Pettigrew Richard
Published: January 2023

When is it legitimate for a government to ‘nudge’ its citizens, in the sense described by Thaler and Sunstein (2008)? In their original work on the topic, Thaler and Sunstein developed the ‘as judged by themselves’ (or AJBT) test to answer this question (Thaler and Sunstein 2008, p. 5). In a recent paper, Paul and Sunstein (2019) raised a concern about this test: it often seems to give the wrong answer in cases in which we are nudged to make a decision that leads to what Paul calls a personally transformative experience, that is, one that results in our values changing (Paul 2014). In those cases, the nudgee will judge the nudge to be legitimate after it has taken place, but only because their values have changed as a result of the nudge. In this paper, I take up the challenge of finding an alternative test. I draw on my aggregate utility account of how to choose in the face of what Ullmann-Margalit (2006) calls big decisions, that is, decisions that lead to these personally transformative experiences (Pettigrew 2019, Chapters 6 and 7).
The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration
Authors: Cook Stuart A.
Published: January 2023

Recent studies have shown IL11 to be pro-fibrotic, pro-inflammatory and anti-regenerative in heart, liver, lung and kidney disease in mice and humans. However, data also show that IL11 is specifically required for appendage regeneration following trauma in some species. In fish, tadpoles and axolotl, IL11 is uniquely upregulated in the regenerative organ, the blastema, following loss of fin, tail or limb. In this short essay I suggest that the pathobiology of IL11 in mammals is rooted in its deep evolutionary role for epimorphic appendage regeneration. In both blastema formation and mammalian disease there is robust IL11-driven fibroblast activation, extracellular matrix production, inflammation and epithelial cell dedifferentiation. While these cellular processes are critical for regeneration in lower species they cause organ failure in mammals. This hypothesis, if correct, may explain the apparent redundancy of IL11 for human health and suggest IL11 as a therapeutic target.

Graphical Abstract
From text to ties: Extraction of corruption network data from deferred prosecution agreements
Authors: Diviák Tomáš , Lord Nicholas
Published: January 2023

Deferred prosecution agreements (DPAs) are a legal tool for the nontrial resolution of cases of corruption. Each DPA is accompanied by a Statement of Facts that provides detailed and publicly available textual records of the given cases, including summarized evidence of who was involved, what they committed, and with whom. These statements can be translated into networks amenable to social network analysis allowing an analysis of the structure and dynamics of each case. In this study, we show how to extract information about which actors were involved in a given case, the relations and interactions among these actors (e.g., communication or payments), and their relevant individual attributes (gender, affiliation, and sector) from five Statements of Fact. We code the extracted information manually with two independent coders and subsequently, we assess the inter-coder reliability. For assessing the coding reliability of nodes and attributes, we use a matching coefficient, whereas for assessing the coding reliability of ties, we construct a network from the coding of each coder and subsequently calculate the graph correlations of the two resulting networks. The coding of nodes and ties in the five extracted networks turns out to be highly reliable with only slightly lower coding reliability in the case of the largest network. The coding of attributes is highly reliable as well, although it is prone to missing data on actors’ gender. We conclude by discussing the flexibility of our data collection framework and its extension by including network dynamics and nonhuman actors (such as companies) in the network representation.
THE ILLEGALITY OF FISHING VESSELS ‘GOING DARK’ AND METHODS OF DETERRENCE
Authors: Bunwaree Priyal
Published: January 2023

Given recent data regarding fishing vessels switching off their Automatic Identification Systems (AIS) in the Western Indian Ocean, this article assesses the potential illegality of the practice by analysing national and international legislation. It shows that the enforcement of AIS laws is generally poor, and although these are becoming increasingly robust in some jurisdictions, the sanctions are not severe enough to act as deterrents. Furthermore, this article suggests that the insurance industry enables the practice of switching off AIS through weak due diligence practices. Insurers have a role to play in curbing such illegal behaviour, and it is not discretionary.
Returning to work: a qualitative study of the experiences of head and neck cancer survivors
Authors: Miller A , Wilson E , Diver C
Published: January 2023

Background

UK head and neck cancer incidence and prevalence in working-age people are increasing. Work is important for individuals and society. Head and neck cancer survivors return to work less than other cancer survivors. Treatment affects physical and psychological functioning long-term. Evidence is limited, with no UK qualitative studies.

Methods

A qualitative study was conducted, underpinned by a critical realism approach, involving semi-structured interviews with working head and neck cancer survivors. Interviews were conducted using the Microsoft Teams communication platform and interpreted using reflexive thematic analysis.

Results

Thirteen head and neck cancer survivors participated. Three themes were drawn from the data: changed meaning of work and identity, return-to-work experiences, and the impact of healthcare professionals on returning to work. Physical, speech and psychosocial changes affected workplace interactions, including stigmatising responses by work colleagues.

Conclusion

Participants were challenged by returning to work. Work interactions and context influenced return-to-work success. Head and neck cancer survivors want return-to-work conversations within healthcare consultations, but perceived these as absent.
Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore
Authors: Wang Yi , Low Fan-Zhe , Low Yin-Yi , Lai Hwa-Sen , Lim Jeong-Hoon , Yeow Chen-Hua , Teerawattananon Yot
Published: January 2023

Objectives

Based on a real-world collaboration with innovators in applying early health economic modeling, we aimed to offer practical steps that health technology assessment (HTA) researchers and innovators can follow and promote the usage of early HTA among research and development (R&D) communities.

Methods

The HTA researcher was approached by the innovator to carry out an early HTA ahead of the first clinical trial of the technology, a soft robotic sock for poststroke patients. Early health economic modeling was selected to understand the potential value of the technology and to help uncover the information gap. Threshold analysis was used to identify the target product profiles. Value-of-information analysis was conducted to understand the uncertainties and the need for further research.

Results

Based on the expected price and clinical effectiveness by the innovator, the new technology was found to be cost-saving compared to the current practice. Risk reduction in deep vein thrombosis and ankle contracture, the incidence rate of ankle contracture, the compliance rate of the new technology, and utility scores were found to have high impacts on the value-for-money of the new technology. The value of information was low if the new technology can achieve the expected clinical effectiveness. A list of parameters was recommended for data collection in the impending clinical trial.

Conclusions

This work, based on a real-world collaboration, has illustrated that early health economic modeling can inform medical innovation development. We provided practical steps in order to achieve more efficient R&D investment in medical innovation moving forward.
Breeding and animal welfare: practical and theoretical advantages of multi-trait selection
Authors: Lawrence AB , Conington J , Simm G
Published: January 2023

The traditional concerns about farm animal welfare have centred around the impact of intensive environments and management practices on the animal. This emphasis on the physical environment is changing, however, with greater consideration being given to animal factors and in particular to the selective breeding of farm animals. In this paper we use examples from our own research on dairy cattle and sheep breeding that have made positive and practical contributions towards reducing welfare problems by creating more balanced breeding programmes. In both examples, inclusion of health and fitness traits into breeding indexes can be shown to be more profitable than selecting on production traits alone. In addition, we propose that in principle animal breeding combined with economics research can make a more general contribution towards resolving animal welfare issues, by providing a framework for the quantitative evaluation of the costs and benefits of an animal production system. The advantage of the approaches currently used in multi-trait selection is that they transform all traits (production-based or welfare-based) to a common currency allowing direct comparisons of costs and benefits. Currently the weights applied to traits reflect their economic value to the producer. This approach is likely to underestimate non-economic welfare aspects such as the pain or discomfort associated with lameness, and new approaches are needed to more fully account for these non-economic welfare costs. We therefore propose that consideration is given to the use of approaches such as contingent valuation, which has been widely used in economics to derive values for non-economic activities. The question of who would pay for the addition of these welfare costs to a breeding index remains open, but it would seem most reasonable to treat these as a public good and pay for them as such through appropriate mechanisms.
What factors should determine cage sizes for primates in the laboratory?
Authors: Buchanan-Smith HM , Prescott MJ , Cross NJ
Published: January 2023

It is imperative to provide adequate quantity and quality of space for all captive animals. Yet practically all guidelines on the housing of primates in the laboratory specify minimum cage sizes based solely on body weight. We argue that no single factor, such as body weight, is sufficient to determine cage size. Instead a suite of characteristics should be used that include morphometric, physiological, ecological, locomotor, social, reproductive and behavioural characteristics. Ideally, the primate's age, sex and individual history should also be taken into account. In this paper we compare this suite of characteristics for some commonly used primates whose weights overlap, to illustrate important differences amongst them. For good animal welfare and good quality science it is necessary to be sensitive to such species differences when determining suitable cage sizes.
Indicators of Physiological Stress in Broiler Chickens During Road Transportation
Authors: Mitchell M A , Kettlewell P J , Maxwell M H
Published: January 2023

Differential leucocyte counts and plasma activities of the muscle enzyme, creatine kinase, have been determined in blood samples obtained from broiler chickens, immediately prior to and following road transportation from farm to processing plant for slaughter. These parameters are proposed as indicators of physiological stress based on previous findings.

Heterophil:lymphocyte ratios and plasma creatine kinase activities increased and eosinophil counts were decreased during the journey in birds tranported in both July and October when the curtain sides of the vehicles were open or closed respectively.

These findings are consistent with the presence of physiological stress during road transportation. The thermal microenvironments to which birds are exposed in transit are thought to represent one of the sources of this ‘transportation stress’.
The Behaviour of Dogs in a Rescue Shelter
Authors: Wells D , Hepper P G
Published: January 2023

Every year sees an increase in the number of dogs admitted to rescue shelters. However well these dogs are cared for in the shelter it cannot be ignored that being in such a situation is stressful, and the time spent in the shelter may change the dogs’ behaviour which may in turn influence their chances of being bought from the shelter. This research examined the behaviour of stray and unwanted dogs on their first, third and fifth days in an Ulster Society for the Prevention of Cruelty to Animals (USPCA) shelter. A questionnaire was also distributed to members of the public to determine how popular the USPCA was as a place from where to purchase a dog, and what factors about a dog's physical characteristics, behaviour and environment influenced potential buyers. Results revealed no significant difference between the behaviour of stray and unwanted dogs although the public viewed stray dogs as much less desirable than unwanted dogs. Time in the shelter had no adverse effects on the dogs’ behaviour. Indeed those changes which did occur during captivity, dogs being more relaxed in the presence of people and eating food more quickly, may be considered as positive changes. The USPCA was viewed as a popular place from which to buy a dog. Of factors influencing the public's choice, the dog's environment and behaviour appeared more important than its physical characteristics. The presence of a toy in the dog's cage greatly increased the public's preference for the dog, although the toy was ignored by the dog. The welfare implications of sheltering dogs are discussed.
The Development of Stereotyped Body Rocking in Chimpanzees(Pan Troglodytes)Reared in a Variety Of Nursery Settings
Authors: Pazol K A , Bloomsmith M A
Published: January 2023

This study measured the amount of time 17 chimpanzee infants devoted to stereotyped body rocking in a variety of nursery settings. Nine females and eight males ranging in age from three weeks to four years were included in the study. Some infants were placed in a peer group at a very early age and were given minimal human contact, while others were provided with more frequent human interaction and were placed in peer groups at varying ages. During the course of the study, infants were housed with varying numbers of chimpanzee companions and some were also provided with a canine companion. Four hundred and thirty-three hours of data were collected. Infants showed a decline in rocking over age and rocked less in the presence of a canine companion. Infant gender, the amount of human contact received at an early age, the age placed with at least one peer companion, and the current number of chimpanzee companions did not affect the time devoted to body rocking. These findings demonstrate that animal managers should look beyond conspecific stimulation for improving the social environment and overall welfare of chimpanzees. These results are further discussed in a framework of identifying possible strategies for minimizing rocking and promoting future behavioural competence in nursery-reared infants.
Group Formation and Behavioural Changes with Release to Free-Ranging in Red Ruffed Lemurs,Varecia Variegata Rubra
Authors: Garrison L K , White F J
Published: January 2023

The social behaviour, ranging, and stereotypic behaviours of four red ruffed lemurs (one female, three males) was observed during group formation and release into a 2.25ha natural habitat enclosure at the Duke University Primate Center (DUPC). The female was immediately dominant to all males and there was no female-male affiliation during the initial stages of group formation. The group became identifiable as a unit after release to free-ranging when affiliation and group vocalizations began. Affiliation and vocalizations continued during subsequent recagings. Male dominance rank reflected relative age, but was subject to reversals. The stresses involved in release and group formation, however, can temporarily produce new aberrant behaviours which are soon replaced by normal behaviours. Once released into the large enclosure, stereotypic behaviours became infrequent but did not disappear. Other novel behaviours such as catatonic huddle and all male huddles were observed during release. Natural habitat enclosures can be important tools in the psychological well-being of captive primates.
The Effects Upon Badgers (Meles Meles) of the Activities of a Single, Persistent Poacher
Authors: Griffiths H I
Published: January 2023

Although the hunters known as ‘terrier men ‘are known to play a significant role in the illicit and cruel persecution of the badger in Britain, very little information is available upon their activities. In this study, detailed records of the hunting practices of a single terrier man, covering a period of seven years, are analysed This provides the first insight into the activities of illegal badger-digging groups, and also emphasizes the extreme stress that may be caused to quarry species during the practice of this illegal sport.
Some Factors Affecting Resting Behaviour of Sheep in Slaughterhouse Lairages After Transport from Farms
Authors: Jarvis A M , Cockram M S
Published: January 2023

The resting behaviour of 64 groups of sheep was observed in the lairages of two slaughterhouses after transport for about four hours in a commercial livestock transporter. The sheep were scanned at five minute intervals for the initial three hours in the lairage pen. The median percentage of time spent lying per group was 17 per cent (range 1 to 63). The percentage of time spent lying was not significantly related to the duration of transport, time of arrival or slaughterhouse. There was a significant positive relationship between space allowance (range 0.22 to 0.98 m2 per sheep) and percentage of time spent lying per group (P < 0.001). Increased space allowance also tended to be associated with a decrease in the occurrence of all interactions between the sheep (P = 0.05). Groups penned with two unfamiliar groups tended to spend less time lying than those penned on their own or with one other group (P = 0.07). There was no significant difference in the total percentage of time spent lying by groups penned on slats and those penned on straw. The results indicated that the ability of sheep to rest in the lairage may be compromised by providing low space allowances.
The Importance of Age/Sex Class Relationships for Captive-Breeding - A Review of Macropodoidea (Kangaroos, Wallabies and Rat-Kangaroos) as a Case Study
Authors: Gansloßer U
Published: January 2023

In this paper social relationships (as defined by Hinde) between age/sex classes of kangaroos, wallabies and rat-kangaroos are reviewed and characterized by frequencies, direction and, where possible, intensity of behavioural interactions, by their patterning in sequences and by distance regulation. Male social organization in the wild for larger non-solitary species is organized in an age/size-related hierarchy. Frequent interactions among equal-sized males stabilize this hierarchy and large males by their simple presence deter younger ones from courting.

Depending on social organization in the wild, the presence of one or more males, sometimes males from different age classes, is desirable from the animal welfare standpoint.

The structure of breeding groups can be greatly improved in terms of welfare and breeding optimization, when a diversity of social relationships are as close to natural conditions as possible.
A Questionnaire Survey of the Correction Methods for Vaginal Prolapse in Ewes
Authors: Scott P R , Sargison N D , Penny C D , Strachan W D
Published: January 2023

A questionnaire on methods of replacement and retention of pre-parturient vaginal prolapse, performed by the shepherd or veterinary surgeon, was completed by 108 veterinary undergraduate students after their farm experience as lambing assistants. The retention methods routinely employed included various suture patterns (72 replies; 66.7%), a plastic intravaginal retaining device (17.6%) and a truss (15.7%). In the sutured group, Buhner perivulval sutures, purse string perivulval sutures and horizontal mattress sutures had been used in 13 per cent, 46.4 per cent and 40.6 per cent of replies respectively. While 5mm nylon tape had been used for 52 of 72 (72.2%) procedures, autoclaved suture material had been used in only 29.6 per cent of replies. No analgesia was employed prior to placing the sutures in 40 (55.6%) replies. Frequent or pronounced abdominal straining by the ewe during replacement of the vaginal prolapse was observed by 69 of 108 respondents (63.9%). On a subjective basis 20 students (18.5%) considered that the welfare consequences of the procedure were a matter of concern and a further 40 students (37.0%) judged that the welfare consequences of the procedure were poor.
Stereotypic Behaviour in Wild Caught and Laboratory Bred Bank Voles (Clethrionymus Glareolus)
Authors: Cooper J J , Nicol C J
Published: January 2023

Stereotypic behaviour is generally associated with animals maintained in restrictive environments, and has rarely been described in wild or free-ranging animals. The difference between captive and wild populations may be due to their genetic predisposition or to experience of environmental factors. To investigate genetic and environmental factors, we compared the behaviour of 12 wild caught voles and their 9 pups with that of 12 laboratory reared voles and 14 laboratory bred pups. All voles were observed twice. Adults were observed after 10 days housing in a cage, containing food, water, sawdust and hay, and again after 60 days. Pups were observed in the same cages 10 and 60 days after weaning. For each observation, the voles’ behaviour was recorded both undisturbed in this cage, and following introduction to an unfamiliar cage. Locomotor stereotypies were observed in laboratory adults, but not in wild caught voles, which spent less time on all locomotor activities and more time under cover than laboratory voles. There was no difference in mortality or fecundity of laboratory and wild caught voles, so there appeared to be no selective advantage to stereotyping. There was no difference in the behaviour of wild and laboratory pups, so early environmental experience of the cage environment, rather than parental background, was an important factor in the development of locomotor stereotypies in this species. Pups that developed stereotypies by 60 days spent less time under cover and more time walking and climbing after 10 days than voles that did not develop stereotypic behaviour. Stereotypic behaviour may therefore have been derived from persistence of locomotor behaviour. Wild caught voles may have failed to develop locomotor stereotypies, either because they did not perform a locomotor response to captivity or because older voles are less prone to develop novel responses to external cues. It would, therefore, be dangerous to use the absence of stereotypic behaviour as a reliable indicator of welfare without taking into account the animal's prior experience.
Effects of Lighting on the Welfare of Domestic Poultry: A Review
Authors: Manser C E
Published: January 2023

Four aspects of lighting which may influence the behaviour and physiology of housed poultry are light intensity, photoperiod, light source and wavelength. These factors are frequently manipulated in an attempt to improve productivity and to facilitate management practices. This review examines the effects of such manipulation upon the welfare of the birds. The majority of papers on lighting in poultry houses deal with their effects upon performance, rather than on factors associated with behaviour and health which may impinge upon welfare. Data about the preferences of birds for different lighting conditions are almost entirely lacking, but the practice of housing birds in relatively low light intensity is considered likely to lead to sensory deprivation in species where vision is important. Tentative recommendations are given pending the results of future research as to appropriate light intensity, photoperiod and light sources for domestic poultry.
Preferences for Nest Boxes as Environmental Enrichment for Laboratory Mice
Authors: Van de Weerd H A , Van Loo P L P , Van Zutphen LFM , Koolhaas J M , Baumans V
Published: January 2023

In nature, mice live in burrows with nest chambers where they breed and may hide from predators. In the laboratory, a shelter or refuge is an easily applicable form of enrichment which may enhance the welfare of laboratory mice by giving them more control over their environment. Six nest boxes made of different materials were evaluated in a preference test with male and female mice of two strains (C57BL/6J and BALB/c). In general, mice showed a preference for cages with a nest box made of grid metal as compared to clear or white perspex nest boxes, or no nest box. They also showed a preference for a cage with a nest box of perforated metal as compared to nest boxes made of grey PVC or sheet metal, or no nest box. When offered a nest box with one open side or a nest box with two open sides, most mice preferred the nest box with one open side and were observed to lie in it with their heads directed towards the opening.

The results of this study show that nest boxes may be used for enrichment purposes in caged mice, although it is not yet entirely clear what are the main features influencing the animals’ preferences. When providing nest boxes as shelters, the structure and design of this type of enrichment should be taken into account, because these may have an effect on the social structure of groups of mice.
Housing and Welfare in Laboratory Rats: The Welfare Implications of Social Isolation and Social Contact Among Females
Authors: Hurst J L , Barnard C J , Nevison C M , West C D
Published: January 2023

Female laboratory rats (Rattus norvegicus; Wistar, Alderley Park) were housed as singletons or groups of three in units of two cages. Units were divided by different types of barrier which allowed varying degrees of social contact across the barrier. Singletons were established either with another singleton on the other side of the barrier or with a group of three as neighbours. Single-housing among females had markedly less effect on time budgeting and pathophysiological measures than among males in a similar, earlier study. In particular, singletons showed a less marked increase in self-directed behaviours, particularly tail chasing, and a smaller reduction in undirected movement around the cage. The smaller reduction in mobility may reflect a greater tendency for singly housed females to attempt escape. Females generally showed much higher levels of escape-oriented behaviours than males and up to a threefold increase in such behaviours when housed singly. Differences in time budgeting and in the apparent significance of social separation between the sexes can be interpreted in terms of differences in socio-sexual strategy and potential mating opportunity, with singleton males responding to their cage as a territory, but singleton females seeking to re-establish social contact. Such an interpretation is consistent with the effects of barrier type on behaviour in singleton females, in which time spent in escape-oriented behaviours reflected the extent to which the barrier facilitated, or frustrated, contact with neighbours.
Perching Behaviour and Preferences for Different Perch Designs Among Laying Hens
Authors: Lambe N R , Scott G B
Published: January 2023

Non-cage systems for housing laying hens often incorporate a framework of perches, allowing birds to move in three dimensions. Wood is predominantly used for perch construction, because it is relatively cheap and easy to work with. However, wooden perches are difficult to clean and disinfect, which could lead to disease and discomfort for the birds using them. The objectives of this study were to identify which characteristics of perch design are preferred by laying hens; and to test whether birds would use perches of alternative materials for a comparable amount of time as they use wooden perches. Six laying hens were housed individually in litter-floored pens and were offered a choice of three pairs of contrasting perch types (experiments 1-3): a rectangular, wooden perch (‘control’) versus two, thin, parallel, rectangular wooden perches; ‘control’ versus a similar perch covered with foam and fabric; and ‘control’ versus a round, wooden perch. Birds were given each pair of perches twice, controlling for perch position in the pen. Time spent on each perch in a 48h period was determined from video records. Preferences were then tested in consecutive trials (experiments 4-5) between perches of the following materials: wood versus plastic versus steel; and wood versus textured aluminium. There were no significant differences in time spent on different perches, suggesting that birds had no preferences between perch types. The implications of these results could be important for the design of alternative systems for laying hens. Birds may be content to perch on artificial materials which could be more hygienic than wood and easier to maintain in a commercial system.