bluuebunny/crossref_metadata_2025 huggingface dataset:
The Musical Orchestra Leadership: An Imagery of Participative and Relational Societal Leadership Style
Authors: ODUNUGA Adeola Funmilayo , Yekini-Ajenifuja Isaac A.
Published: September 2022

The issue of leadership in society has been of major concern from times immemorial, this is because it is believed that the quality of leadership is one of the major determinants of societal development. The existing societal leadership style in Nigeria seems not to help the populace in meeting societal needs and satisfying human aspirations, hence there is a need for an improved leadership style that will help in the attainment of societal and individual goals. Using existing leadership theories, this paper explains the ideals of a good participative and relational leadership style using metaphoric inference of an orchestra and its conductor.  The study is an ethnographic study that used oral interviews and other qualitative techniques to obtain its information. The research discovered that with a competent leader (conductor) at the head of a team of members (the orchestra), society is capable of doing great as long as everyone does their specific roles.  Societies will fare well if the ideas of this imagery are adopted. The paper recommends that the younger generation should be encouraged to learn and adopt participative and relational leadership styles.
Expressions and Meanings: A Phenomenological Approach to Semantics
Authors: LIELE MADZOU Desmond Auffrey
Published: September 2022

This article aims to analyze the relationship between ''saying'' and the ''meaning of saying'' under the banner of phenomenology. It is a question of resolving the conflict between the enunciation as the communicative background of an axiom and the content of knowledge as the intention of a thing. This is the problem of language and of the ontological description of the expressed object. This research tends to put back on the table of philosophy the claim of formal logic to want, wrongly, to claim to define the fundamental meanings by semantics. This research aims to posit saying as an expression referring to something. It reveals the uniqueness that naturally exists between saying and meaning in the noema-noesis relationship. Aware that all of life is language, this article sets out to establish the distinction between modes of reasoning and forms of reasoning in order to account for meanings as the meaning of saying. By scrutinizing the notion of judgment, it follows that significations as expressed meaning are phenomena.
Basic Education Concerns Under the Double Alleviation Policy and Countermeasures: A Case Study of Taizhou City in China
Authors: Yu Yanyan
Published: September 2022

When the Double Alleviation policy was issued, the People’s Republic of China Law on Family Education Promotion was also released. The author identifies three significant problems in primary and secondary education using the questionnaire survey: the anxiety of students, parents and teachers; the unbalanced distribution of quality educational resources; and the lack of innovative power in school education management. In this regard, it proposes to build a new system of shared governance among stakeholders through multi-party efforts, develop a systematic plan to promote the balanced development of high-quality educational resources and improve the mechanism to broaden the channels for teacher professional development in primary and secondary education. At the same time, it proposes to integrate resources for increased instructions of comprehensive courses and integrate the social welfare services of universities with the primary and secondary education off-campus activity platforms.
Imperial Patchwork “Flickenteppiche” as a Historical Metaphor for Chaos, Federalism and Diversity
Authors: Wüst Wolfgang
Published: September 2022

With the recent research on the importance of the Estates, whose function often went far beyond questions of taxation, the Imperial Circles and the simultaneous deconstruction of European state formation as an absolutist top-down process the view of the “co-organizing intermediate levels” changed. This is how Johannes Burkhardt described these regional images in 2006 in “Gebhardt. Handbuch der Deutschen Geschichte.” The new view of the Old Empire has been well received by research in regional history, especially since differentiations on small-scale rule and organization in Bavaria, Baden-Württemberg, Hesse, Thuringia, Saxony and other federal states have traditionally been and still are part of the core business of this discipline. “Flickenteppiche” as colourfully woven objects of diversity are certainly still products in demand in the textile industry and consumer society, but they are just as unsuitable as an explanatory model for the coherence of the Empire and its Imperial Circles as they are for analyzing power and rule in the early modern period. In their figurative meaning of the word, patchwork carpets ignore communicative processes for decision-making just as much as they register cross-border action and design as a quantité négligeable.
En-garde: Source Evaluations in the Digital Age
Authors: Denton Courtney A. , Muis Krista R. , Dubé Adam K. , Armstrong Skylar
Published: September 2022

Students have difficulty assessing the quality of information. They often rely on content-focused criteria to make reliability assessments and, as a result, may accept inaccurate information. Despite the impact of poor source evaluation skills, educational researchers have not widely examined source evaluation behaviours in authentic environments or tasks. Students’ epistemic cognition, or their thinking about the epistemic properties of specific knowledge claims and sources, is one promising avenue to better understand their source evaluation behaviours. Two studies were conducted to explore students’ epistemic thinking. In Study 1, college students (n = 12) reported their reliability criteria in focus group interviews. Four of these participants (n = 4) also examined the reliability of an online news article. Grounded theory was used to infer students’ epistemic ideals and reliable epistemic processes. In Study 2, students (n = 43) rank-ordered two news articles and justified how they assigned each article’s rank in a written response. Most students were able to accurately rank-order the articles using relevant epistemic processes. Cluster analysis was used to characterize the evaluation criteria used. Surprisingly, more participants who justified their decisions using relevance criteria accurately rank-ordered the articles. The role of direct and indirect indicators of reliability are discussed through the lens of the Apt-AIR framework of epistemic thinking.
3D sensor network location spatial positioning technology based on machine learning
Authors: Lu Zhiyong , Tan Xiaodan
Published: September 2022

The purpose of this paper is to combine machine learning to locate the 3D sensor network space. Real life is mostly a three-dimensional environment. Whether it is a factory in manufacturing or a vegetation base in agriculture, it needs to be monitored and positioned. In this paper, the localization algorithm is discussed to a certain extent. This paper firstly introduces the relevant background and organizes related work. It also wrote related algorithms, such as ranging-based positioning algorithms in the free space of wireless sensors. It shows the positioning link by introducing the wireless sensor network structure system and node structure. And this paper summarizes the Bounding-box Method positioning principle, TDOA algorithm principle, and TDOA positioning principle. It then describes the gradient boosting tree classification algorithm based on machine learning, and focuses on the admiral boosting tree classification algorithm related to the experiment. This paper also describes the ranging technology combining RSSI algorithm and DV-Hop algorithm in three-dimensional space, and mentions two algorithms of RSSI and DV-Hop. In the fourth part, the machine learning coordinate prediction accuracy improvement experiment and the three-dimensional space positioning algorithm optimization experiment and result analysis are carried out. It is proved by experiments that the model evaluation effect of the gradient boosting tree classification algorithm in machine learning is the best. It can be applied to the calculation of relative position coordinates of label nodes. It then carried out the three-dimensional positioning effect test experiment of IDV-Hop algorithm. This shows that when the network density in the experimental environment reaches more than 12, the localization coverage of IDV-Hop algorithm and DV-Hop algorithm are both higher than 91%. Finally, the hybrid algorithm of RSSI and DV-Hop algorithm is used to compare the positioning accuracy, positioning coverage and bad node rate with these two algorithms. It draws the stability of the hybrid algorithm and its effects, and finally discusses and summarizes the experiments.
Causation and decision: On Dawid’s “Decision theoretic foundation of statistical causality”
Authors: Pearl Judea
Published: September 2022

In a recent issue of this journal, Philip Dawid (2021) proposes a framework for causal inference that is based on statistical decision theory and that is, in many aspects, compatible with the familiar framework of causal graphs (e.g., Directed Acyclic Graphs (DAGs)). This editorial compares the methodological features of the two frameworks as well as their epistemological basis.
Continuous glucose monitoring in an infant with panhypopituitarism having hypoglycemia on growth hormone therapy
Authors: Kiuchi Kaho , Sato Takeshi , Nakano Satsuki , Ishii Tomohiro , Hasegawa Tomonobu
Published: September 2022

Objectives

The usefulness of continuous glucose monitoring (CGM) in infants with panhypopituitarism (PH) having hypoglycemia is yet to be explored. The potential adverse effects of growth hormone (GH) replacement therapy, such as hyperglycemia, cannot be comprehensively evaluated using the conventional measurement.

Case presentation

A 2-month-old infant with PH, including severe GH deficiency, had hypoglycemia despite frequent feeding. Glucose levels were monitored using CGM before and after GH replacement therapy. The proportion of time for hypoglycemia decreased from 4.9 to 0% (p<0.017). Hyperglycemia did not increase. The CGM method did not contribute to any adverse events requiring intervention. Our patient only experienced minor bleeding and no episode of cellulitis.

Conclusions

CGM is useful in controlling glucose levels in infants with hypoglycemia and PH.
No pubertal growth spurt, rapid bone maturation, and menarche post GnRHa treatment in girls with precocious puberty
Authors: Briscoe Audrey , Chen Katherine , Klein Karen O.
Published: September 2022

Objectives

To study total growth, rate of bone maturation, and menarche after discontinuation of Gonadotropin releasing hormone agonist (GnRHa) treatment for central precocious puberty (CPP).

Methods

Twenty girls with CPP on treatment with GnRHa were followed from discontinuation of treatment to final height (FH). Height, height velocity (HV), and bone age were measured every 6 months. Age at menarche was collected.

Results

Once treatment is discontinued, rate of bone maturation (bone age [BA]/chronological [CA]) accelerated from 0.7 ± 0.3 at end of treatment to 1.2 ± 0.8 post treatment, similar to BA/CA prior to treatment. BA at treatment discontinuation ranged from 11–14 years. On average, treatment was stopped when CA was within 9 months of BA. All girls continued to grow from end of treatment to menarche averaging an increase of 4.7 ± 3.7 cm, with HV 3.2 ± 2.0 cm/year. Post-menarche they grew an additional 4.6 ± 2.1 cm, with HV 2.4 ± 1.9 cm/year. Acceleration of HV was not seen post treatment. The younger the BA at initiation or completion of treatment, the longer time to menarche. No one had menarche prior to a BA of 12.5 year.

Conclusions

A pubertal growth spurt does not usually occur after treatment with GnRHa in girls with CPP. Rate of bone maturation accelerates post treatment. These factors are important in assessing optimal height outcome and decisions regarding cessation of treatment. This study will help clinicians give patients and families better estimates of growth and onset of menarche post treatment.
TGF-β1 upregulates Sar1a expression and induces procollagen-I secretion in hypertrophic scarring fibroblasts
Authors: Ahn Keun Jae , Kim Jun-Sub
Published: September 2022

Hypertrophic scarring (HTS) is a common fibroproliferative disorder that typically follows thermal and other injuries involving the deep dermis. The underlying pathogenic mechanisms are regulated by transforming growth factor-β (TGF-β); however, the exact mechanisms in HTS have not been elucidated. We conducted this study to explore the cellular signaling mechanisms for expression of Sar1a, a coat protein complex II-associated small GTPase, in HTS fibroblasts (HTSF). We found that Sar1a was upregulated in HTSF as compared to that in normal fibroblasts. Furthermore, stimulation of TGF-β1 increased the expression of Sar1a in HTSF, and small interfering RNA for Sar1a suppressed procollagen-I (PC-I) secretion. Next we investigated the signaling mechanism from TGF-β1 to Sar1a expression and its association with PC-I secretion. In the presence of TGF-β-activated kinase 1 (TAK1), c-Jun N-terminal kinase, or p38 inhibitors, the effect of TGF-β1 on Sar1a expression and PC-I secretion significantly decreased; however, it had no effect on collagen-1A (Col-1A) expression. Further, the inhibitors of Smad3 or extracellular signal-regulated kinases inhibited TGF-β1-induced Col-1A expression but had no effect on PC-I secretion and Sar1a expression. Taken together, our results suggested that TGF-β1 induces Sar1a expression through TAK1 signaling and this signaling event regulates PC-I secretion in HTSF.
Entropy production simulation of second-grade magnetic nanomaterials flowing across an expanding surface with viscidness dissipative flux
Authors: Jamshed Wasim , Gowda Ramanahalli Jayadevamurthy Punith , Kumar Rangaswamy Naveen , Prasannakumara Ballajja Chandrappa , Nisar Kottakkaran Sooppy , Mahmoud Omar , Rehman Aysha , Pasha Amjad Ali
Published: September 2022

The principal focal point of the current review is the second-grade nanofluid (SGNF) stream with slanted magnetohydrodynamics and viscous disintegration impacts across a moving level flat surface with entropy investigation. Here, we have done a comparative study on copper–methanol and iron–methanol second-grade nanoliquids. The governing conditions of the SGNF model are changed into ordinary differential equations (ODEs) by using supportive changes. To tackle the non-straight ODEs, the Runge-Kutta Fehlberg-45 procedure is utilized. The result reveals that the velocity gradient of copper–methanol second-grade nanoliquid is strongly affected by suction, magnetic, and second-grade fluid parameters and declines faster when compared to iron–methanol second-grade nanoliquid. Copper–methanol SGNF shows improved heat transfer than iron–methanol SGNF for improved values of Eckert and Biot numbers.
“‘Peewit,’ said a peewit, very remote.” – Notes on quotatives in literary translation
Authors: Vișan Nadina
Published: September 2022

The present article focuses on strategies of translating fiction quotatives from English into Romanian. Starting from the definition of quotatives as structures that in their simplest form consist of a subject and a quoting verb and accompany a quotation, I have selected two samples of literary text and their respective multiple versions so as to investigate patterns in which these structures are translated. Because, as pointed out in the literature, fiction quotatives describe narrative-advancing events and contribute to the development of characters, the investigation of how fiction quotatives are translated (in particular how say, the most frequently used verb in quotatives, is treated in translation) might prove to offer valuable insight for literary translation studies, correlating tendencies that seem to be cross-linguistic. For instance, it has been demonstrated that in Spanish there is a tendency of replacing the generic quoting verb say with other manner of speaking verbs. This may be seen as a form of “enrichment” as a translation strategy. The article advances the hypothesis that a similar phenomenon can be attributed to Romanian and links this phenomenon to parametric variation in English and Romance.
Modeling, simulation and mixing time calculation of stirred tank for nanofluids using partially-averaged Navier–Stokes (PANS) k

u
− ϵ

u
turbulence model
Authors: Maji Srimanta , Sahu Akshaya K.
Published: September 2022

The present study deals with the numerical simulation of stirred tank in the presence of nanofluids to see the effect of different volume fraction (ϕ) of nanoparticles on the behaviour of flow characteristics and for the calculation of mixing time in the entire tank. The flow is assumed to be steady, axisymmetric, two dimensional and incompressible. For the simulation of flow inside the vessel, partially-averaged Navier–Stokes (PANS) k

u
 − ϵ

u
turbulence model is used. Control volume method has been taken to descretize the governing equation along with power-law schemes. Further, semi-implicit method for pressure-linked equations revised (SIMPLER) algorithm and line-by-line tri-diagonal matrix algorithm (TDMA) have been taken to obtain the solution. The objective is to investigate the influence of ϕ on the characteristic flow variables and to calculate mixing time for different ϕ of nanofluids and for different values of f

k
, PANS model parameter. It is noted that with the increase in ϕ, mixing time has also been increased and it increases very fast for PANS k

u
 − ϵ

u
model with the increase in filter width f

k
.
Malic acid: fermentative production and applications
Authors: Yadav Mukesh , Sehrawat Nirmala , Kumar Sunil , Sharma Anil Kumar , Singh Manoj , Kumar Amit
Published: September 2022

Microbial metabolites have gained lot of industrial interest. These are currently employed in various industries including pharmaceuticals, chemical, textiles, food etc. Organic acids are among the important microbial products. Production of microbial organic acids present numerous advantages like agro-industrial waste may be utilized as substrate, low production cost, natural in origin and production is environment friendly. Malic acid is an organic acid (C4 dicarboxylic acid) that can be produced by microbes. It is also useful in industrial sectors as food, chemicals, and pharmaceuticals etc. Production/extraction of malic acid has been reported from fruits, egg shells, microbes, via chemical synthesis, bio-transformation and from renewable sources. Microbial production of malic acid seems very promising due to various advantages and the approach is environment-friendly. In recent years, researchers have focused on fermentative microbial production of malic acid and possibility of using agro-industrial waste as raw substrates. In current article, malic acid production along with applications has been discussed with recent advances in the area.
Properties of fresh and hardened self-compacting concrete incorporating rice husk ash: A review
Authors: Zhang Peng , Wei Shiyao , Cui Guo , Zhu Youcai , Wang Juan
Published: September 2022

Rice husk is considered as a waste product of farming. However, rice husk ash (RHA) has a good pozzolanic activity, which can be used in cement-based materials as a supplementary cementitious material (SCM), and it is also suitable for self-compacting concrete (SCC). This study reviews the physical and chemical properties of RHA and the properties of RHA–SCC mixtures such as fresh properties (crucial factors and evaluation methods of workability for fresh SCC), mechanical properties (compressive strength, splitting tensile strength, flexural strength, and modulus of elasticity), and durability (water absorption and sorptivity, acid resistance, chloride penetration resistance, electrical resistivity, and alkali silica reaction). It was observed that the workability of SCC decreases with an increase in the incorporation rate of RHA. An incorporation rate of RHA in the range of approximately 15–20% enhances the mechanical properties and durability of SCC. The incorporation of RHA into SCC can reduce the environmental burden of rice husk treatment, and promote sustainable development of cement industries and reduce the cost of SCC.
Hippocampal-Prefrontal θ Coupling Develops as Mice Become Proficient in Associative Odorant Discrimination Learning
Authors: Ramirez-Gordillo Daniel , Bayer K. Ulrich , Restrepo Diego
Published: September 2022

Learning and memory requires coordinated activity between different regions of the brain. Here, we studied the interaction between infralimbic medial prefrontal cortex (mPFC) and hippocampal dorsal CA1 during associative odorant discrimination learning in the mouse. We found that as the animal learns to discriminate odorants in a go-no go task, the coupling of high-frequency neural oscillations to the phase of θ oscillations (θ-referenced phase-amplitude coupling or tPAC) changes in a manner that results in divergence between rewarded and unrewarded odorant-elicited changes in the θ phase-referenced power (tPRP) for β and γ oscillations. In addition, in the proficient animal there was a decrease in the coordinated oscillatory activity between CA1 and mPFC in the presence of the unrewarded odorant. Furthermore, the changes in tPAC resulted in a marked increase in the accuracy for decoding contextual odorant identity from tPRP when the animal became proficient. Finally, we studied the role of Ca2+/calmodulin-dependent protein kinase IIα (CaMKIIα), a protein involved in learning and memory, in oscillatory neural processing in this task. We find that the accuracy for decoding the contextual odorant identity from tPRP decreases in CaMKIIα knock-out mice and that this accuracy correlates with behavioral performance. These results implicate a role for tPAC and CaMKIIα in olfactory go-no go associative learning in the hippocampal-prefrontal circuit.
Systematic Literature Review terhadap Pemanfaatan Internet of Things (IoT) dalam Bidang Kesehatan
Authors: Adauwiyah Hofifah Isma , Kamaluddin Muhammad Ridho , Al Kautsar Ryo Figo , Fitroh Fitroh
Published: September 2022

Saat ini Internet of Things (IoT) semakin berkembang pesat. Dengan teknologinya yang canggih, IoT mampu memberikan berbagai dampak positif, seperti efisiensi, efektivitas dan kecepatan dalam melakukan tugas tertentu, terutama dalam bidang kesehatan. Keberadaan IoT dalam bidang kesehatan ini sangat penting dalam memantau kondisi pasien secara cepat dan praktis. Banyaknya penelitian tentang pemanfaatan IoT di bidang kesehatan dapat membantu peneliti atau pihak terkait dalam melakukan pengembangan IoT di dunia medis. Oleh karena itu, diperlukan literature review terkait pemanfaatan IoT di bidang kesehatan agar informasi dapat diklasifikasikan secara sistematis. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis penelitian-penelitian terbaru terkait pemanfaatan IoT di bidang kesehatan dari tahun 2020 sampai 2021 menggunakan metode Systematic Literature Review (SLR) dengan bantuan tools Publish or Perish, Mendeley, Zotero, dan Microsoft Excel. Hasil penelitian menunjukkan bahwa dari 129 artikel IoT pada Quartile 1 tahun 2020-2021, terdapat 10 artikel terkait IoT di bidang kesehatan yang terbagi menjadi 4 topik, di mana topik yang paling banyak diteliti adalah dampak langsung IoT di bidang kesehatan, yaitu dengan persentase sebesar 50%, lalu diikuti topik efisiensi pengiriman data terkait penggunaan IoT di bidang kesehatan sebesar 20%, masalah keamanan terhadap IoT di bidang kesehatan sebesar 20%, serta penggunaan atau pemakaian energi pada IoT di bidang kesehatan sebesar 10%.
Evaluating Social Technology Utilization on Employee Performance Using Positivism Paradigm
Authors: Huda Muhammad Qomarul , Irawan Romi , Kumaladewi Nia , Koondhar M. Yaqoob
Published: September 2022

Employees who are performing are assets in an organization to improve effectiveness and efficiency of work. The use of Social Technology has experienced a significant increase in the context of the company to help employee performance. This study proposes a model of employee performance measurement in terms of the use of Social Technology. The method used is a quantitative method with an extended Social Technology model. This model has seven variables: collaboration, communication, frequency of access, resource sharing, usefulness as independent, employee performance as dependent and social technology use which is the mediator. In its testing using PLS-SEM data analysis technique with SmartPLS 3.0. The test results show that there are six hypotheses tested, with five hypotheses accepted or influential and one hypothesis not accepted. Five accepted hypotheses prove that collaboration, communication, resource sharing, and usefulness have a significant effect on the use of Social Technology use and the use of Social Technology use which has a significant relationship to employee performance.
Analisis Tingkat Kerawanan Longsor di Sub Daerah Aliran Sungai Cisangkuy, Citarum Hulu Kabupaten Bandung Menggunakan Metode Skoring
Authors: Julaeha Siti , Kendarto Dwi Rustam , Solihin Muhammad Amir
Published: September 2022

Sub DAS Cisangkuy memiliki bentuk lahan berupa perbukitan hingga pegunungan, didominasi oleh kemiringan lereng agak curam dan curam. Karakteristik wilayah tersebut menyebabkan Sub DAS Cisangkuy termasuk daerah yang rawan terjadi bencana longsor. Penelitian ini bertujuan untuk mengetahui karakteristik wilayah melalui parameter kerawanan longsor dan memetakan sebaran tingkat kerawanan longsor di Sub DAS Cisangkuy memanfaatkan Sistem Informasi Geografis (SIG). Penelitian ini menggunakan metode analisis spasial berupa tumpang susun atau overlay, skoring dan pembobotan. Model yang digunakan merujuk pada pendugaan Puslittanak tahun 2004 dengan parameter berupa curah hujan, kemiringan lereng, jenis tanah, jenis batuan penyusun (geologi), dan penggunaan lahan. Hasil penelitian menunjukkan bahwa Sub DAS Cisangkuy didominasi oleh macam tanah andosol eutrik, jenis batuan vulkanik, kemiringan lereng 16-25%, penggunaan lahan hutan, dan intensitas curah hujan rata-rata tahunan 2001-2500 mm/tahun. Terdapat 3 tingkat kerawanan longsor di Sub DAS Cisangkuy diantaranya tingkat kerawanan rendah seluas 1293,91 ha (4,54%), kerawanan sedang seluas 6698,59 ha (23,48%), dan kerawanan tinggi seluas 20537,5 ha (71,99%).
Performance of Multi-Criteria Recommender System Using Cosine-Based Similarity for Selecting Halal Tourism
Authors: Nadhifah Rizqi Aulia , Arif Yunifa Miftachul , Nurhayati Hani , Angreani Linda Salma
Published: September 2022

Tourism is an activity where people or groups travel voluntarily for relaxation, seeking entertainment, or enjoy cultural diversity both within the city, outside the city, or even abroad. For traveling, information about halal tourism is essential that tourists must know. Tourists can contact a tour guide to find information and recommendations for halal tourism. However, it will cost quite a bit and need for a recommendation system to obtain recommendations and make it easier for tourists to determine which halal tourism to visit. This study aims to obtain the Multi-Criteria Recommender System's (MCRS) performance using cosine-based similarity to select halal tourism in Batu City. MCRS extends the traditional approach by using more than one scoring criteria to generate recommendations. The implementation of MCRS using cosine-based similarity succeeded in producing the five highest recommendations for halal tourist attractions, which were implemented in a game-based system. Through recommendation accuracy testing on two items, three items, four items, and five tourist attractions items, we obtained an average accuracy is 77,95%.
Özgeci Değerin Sürdürülebilir Tüketici Tutum ve Davranışlarına Etkisi
Authors: ÇAYIRAĞASI Filiz
Published: September 2022

Sürdürülemez tüketim kalıplarından artan bilincin doğrudan davranışa yansıdığı sürdürülebilir tüketim şekillerine giden süreçte değer, tutum, davranış arasındaki ilişkilerin derinleştirilmesi daha da kritik bir hal almaktadır. Bu araştırmanın amacı, tüketicilerin özgeci değer düzeylerinin, sürdürülebilir tüketici tutumuna ve sürdürülebilir tüketici davranışına etkisini incelemektir. Bu bağlamda kolayda yöntemi ile örnekleme yöntemi ile çevrimiçi anket aracılığı ile 520 katılımcıdan veri toplanılmıştır. Araştırmada kapsamında toplanan bu veriler, istatistiksel programlar aracılığıyla öncelikle normallik testine daha sonra da korelasyon, faktör ve regresyon analizine tabi tutulmuştur. Analiz bulgularına göre özgeci değer ile sürdürülebilir tüketici tutumu arasında yüksek düzeyde ve pozitif yönlü bir ilişki olduğu ve özgeci değer ile sürdürülebilir tüketici davranışı arasında orta düzeyde ve pozitif yönlü bir ilişkili olduğu bulgusuna ulaşılmıştır. Bunun yanında özgeci değer sürdürülebilir tüketici tutumunu ve sürdürülebilir tüketici davranışını pozitif olarak etkilediği ve bunun yanında özgeci değerin sürdürülebilir tüketici tutumunu ve sürdürülebilir tüketici davranışını arttırdığı sonucu da elde edilmiştir. Ayrıca analiz bulguları ışığında, tüketicilerin özgecil değer ile tutum arasındaki ilişki düzeyi yüksekken, özgecil değer ile sürdürülebilir davranış arasındaki ilişki düzeyinin orta düzeyde olduğu gözlemlenmiştir. Sonuçlarımız alan yazında addedilen “yeşil boşluğun” kapatılması adına değer, tutum, davranış şeklindeki üçlü yapı ve bağıntıları temelinde sürdürülebilir tüketici davranışları anlamak, engelleri öngörmek ve yorumlamak için kritik bir anlayış sunmaktadır.
CUT&RUN with Drosophila tissues v1
Authors: Ahmad Kami
Published: September 2022

We have modified the Cleavage Under Targets and Release Using Nuclease (CUT&RUN) method for epigenomic profiling of histone modifications and chromatin proteins to use dissected Drosophila tissues. In CUT&RUN, cells or tissues are permeabilized and incubated under conditions where a factor-specific antibody can bind at sites of a chromatin protein. This antibody is then used to tether a protein A-micrococcal nuclease fusion protein, which upon activation releases specific protein-DNA complexes into the supernatant for paired-end DNA sequencing, and leaving the vast majority of DNA behind in the cellular pellet. CUT&RUN outperforms the most widely used Chromatin Immunoprecipitation (ChIP) protocols in resolution, signal-to-noise, and depth of sequencing required. Previous versions of CUT&RUN have used isolated nuclei, mammalian cultured cells, or yeast spheroplasts. Here we have modified the CUT&RUN protocol to manipulate imaginal discs and tissues dissected from larvae with magnetic beads without isolation of cells or nuclei. About 10 imaginal discs provides high-quality data for a histone modification or for a chromatin factor. A simple spike-in strategy is used for accurate quantitation of experiment yields and library preparation. From larvae to purified DNA, CUT&RUN requires 1-2 days with minimal handling after dissection.
Desquamative gingivitis as a sole presentation in mucous membrane pemphigoid: A rare case report with a brief review of literature
Authors: Hasan Shamimul
Published: September 2022

Desquamative gingivitis refers to an erythematous, ulcerated, or atrophic appearance of the gingiva. This clinical appearance is common to a number of pathologies, most frequently accounting for mucocutaneous autoimmune entities (Oral lichen planus and Mucous membrane pemphigoid). The oral physician must be well versed with its varied clinical presentations, and a prompt diagnosis is essential for early remission from this debilitating state.
Assessment of fear factors and practice related modifications in response to COVID-19 pandemic outbreak among dental practitioners in Thiruvananthapuram District, Kerala
Authors: Mohamed Shahana C , Ambika Suchitra , Pereira Shibu Godfrey
Published: September 2022

Dentists are more vulnerable to the SARS-CoV-2 virus infection as they work close to the patient and viral transmission by saliva has proven to be the commonest source of disease transmission. In this scenario, it is natural for dental practitioners to be afraid of getting infected with COVID-19. As a strategy to continue dental practice in the pandemic, it is also pertinent to assess the dentist’s knowledge of practice modifications in the dental setting.

A cross-sectional study was conducted among dental practitioners registered with the Indian Dental Association local branch to assess the fear, anxiety, and knowledge regarding practice modifications. Data collection was done through google forms and commenced after obtaining informed consent from the study participants. Eight factors each corresponding to fear and knowledge on practice modifications pretested and validated were administered to the dental practitioners. Anxiety was assessed using the Coronavirus Anxiety Scale (CAS).

: Nearly 46 percent of dental practitioners presented with moderate fear. Fear related to transmitting the infection to family (84.4%), treating patients with symptoms (76.6%), and getting infected from patients or co-workers (53.1%) were the common fear factors reported by the dental practitioners. Increased fear was significantly associated with females, specialist dentists, and those working in the government sector. CAS score >9 was reported only by 1.3% of dental practitioners, indicative of probable dysfunctional corona-related anxiety. Good knowledge of practice-related modifications in COVID times was reported by 47.4% of dental practitioners.

The study highlighted a considerable amount of fear among dental practitioners. Psychological support mechanisms to facilitate the mental health of dental practitioners such as regular counseling sessions till the wane of the pandemic, followed by a few years post-pandemic, and implementing periodic mental health screening need to be implemented by the Government and concerned health authorities.
Impact of COVID-19 pandemic on the utilization of OPD services of a tertiary dental care centre in New Delhi, India
Authors: Chawla Kirti , Sawai Madhuri Alankar , Jafri Zeba , Sultan Nishat , Bhardwaj Ashu , Singh Sanjay , Kaur Mandeep
Published: September 2022

In March 2020, there was COVID-19 pandemic outbreak in India with the second wave entering in April 2021. This hampered the day to day life of most of the people. Patients visiting the Dental OPDs were reduced. This retrospective analysis assessed the effect of COVID-19 on the demographics and complaints of patients visiting the dental OPD.

To assess how the current COVID-19 pandemic has influenced the utilization of OPD services by patients in a tertiary care centre in New Delhi.

This was a retrospective study. The data (August 2020 to February 2021) of patients visiting the Dental OPD of Faculty of Dentistry, Jamia Millia Islamia was retrieved and analyzed. 4909 patients visited the OPD with various complaints. Their demographic characteristics, reasons for visiting and treatment rendered were analyzed.

Out of 4909 patients visiting the dental OPD almost equal males (49.9%) and females (50.1%) visited. The mean age of the patients was 32.84±16.12 years. Caries and pain were the main chief complaints. 31% had caries and 22% had pain. 33.7% had endodontic problems and 24.8% had periodontal problems. Only 5% pediatric patients visited the OPD. 45% patients were medicated and 26.6% were referred to a higher centre.

Within the constraints of this study, we found that most of the patients visited the dental OPD only if they had endodontic problems like pain and caries.
Comparative evaluation of management of oral lichen planus using three different modalities: A clinical study
Authors: Prasanth T , Manandhar Sumita , Gupta Nitin , Kumar Pramod
Published: September 2022

: Oral lichen planus (OLP), a chronic inflammatory mucocutaneous disorder varying in appearance, affects the mucus membrane of the oral cavity and is potentially premalignant. Various therapeutic regimens have been developed for the management of OLP highlighting steroids as a first-line therapeutic procedure. Recently, modalities like lasers, photodynamic therapy (PDT), photobiomodulation (PBM) has also been mentioned in the literature to be equally effective with minimal intervention.

: A total of 15 known cases of OLP were randomly allocated into three groups; topical corticosteroid applications, diode laser ablation (980 nm), and photodynamic therapy. Patients were evaluated for RAE score, Oral health-related quality of life (OHRQoL) using the VAS score following the intervention.

: Applications of PDT and diode laser ablation proved effective in the resolution of symptoms in RAE scoring and OHQOL and has proved that these have a bright future to evolve as a future trend.

: Modalities like lasers ablation and PDT open new dimensions in the management of OLP providing safe and effective alternative techniques compared to the conventional method.
Periodontal management of compromised abutment for rehabilitation of aesthetic zone: A case report
Authors: Bahri Rahul , Rath S.K. , Prakash Poonam
Published: September 2022

Fixed Dental Prosthesis is a treatment modality to replace the missing tooth by utilizing the adjacent teeth as abutments. The health, periodontal surface area, crown root ratio and other parameters govern the condition of abutment. The examination of these teeth by clinical and radiographic parameters determine its usage as abutments to support and retain the prosthesis. Adjunctive therapy like crown lengthening, foundation restorations and others can be used to improve the condition of abutments keeping in mind the basic periodontal and prosthodontic principles. This case report highlights the importance of Perio-Prostho relationship in successful rehabilitation of a questionable abutment in esthetic region.
Simultaneous gingival depigmentation and crown lengthening in esthetic periodontal prosthodontic rehabilitation
Authors: Mubarak Ramy , Moussa Sarah Gamal , Amer Sherif Abdelrahman
Published: September 2022

Evolution in esthetic dentistry have reshaped the demand for having a perfect smile into a need. Enormous advancements in armamentarium, surgical techniques and material sciences have raised the aspiration of patients for having the desired esthetic outcomes in minimum dental visits. Ample cases are reported in the literature having excessive gingival display and hyper pigmentation treated with simultaneous gingivectomy and depigmentation. However, evidence for simultaneous depigmentation and crown lengthening with osseous resection are scarce. The patient in this paper had gingival hyper pigmentation and excessive gingival display with high osseous crest levels. Simultaneous depigmentation and crown lengthening with osseous recontouring was performed in a single visit. Prosthetic rehabilitation proceeded following healing to replace functionally and esthetically unpleasing anterior crowns, restore hard tissue wasting disease, as well as replace missing posterior teeth.
Multifaceted presentation of peripheral ossifying fibroma: Case series spanning three age groups
Authors: Gopalakrishnan Ambili , Madhavanpillai Baiju Radhamoni , Kannappillil Binitta Paul , Balan Jithin
Published: September 2022

A benign focal non-reactive lesion that has been reported in the literature under a variety of names, Calcifying Fibroblastic Granuloma or Peripheral Ossifying Fibroma (POF) can occur usually in a younger age group with a female predilection. POF can be perplexing to a clinician as the clinical similarity with pyogenic granuloma or fibroma is astounding. It can cause erosion of bone and underlying structures with a recurrence rate ranging from 16% - 20%. So, the lesion must be identified by histological investigation. In this paper, we describe about three individuals in their 2, 5, and 9 decades of life who were all diagnosed with POF.

POF can be perplexing to a clinician as the clinical similarity with pyogenic granuloma or fibroma is astounding. The lesion has a predilection for females of younger age group. Only 0.5% cases of POF have been reported in the third decade of life which makes the third case a unique one. The three cases presented here were managed using three different surgical approaches.
Gum health: A short communication
Authors: Bharadwaj Pooja , Patel Roopali
Published: September 2022

Human being is creature that is blessed with a knowledge and curiosity. The human being is recognized by a human body that varies genotypically but is somewhat similar phenotypically. The knowledge gaining

of the human being is reflected in the form of speaking ,and this speaking is mainly a function of tongue and teeth. Gums are a structure that surrounds the teeth and in the dental terminology, the gums are called as the gingiva. These gums are of utmost importance both from oral health point of view and from systemic health point of view. In this short communication the importance of gum health and their correlation with oral health and systemic health is emphasized.
Antioxidants in oral medicine: A review
Authors: Joshi Sidharth Shrikant , Pandharbale Atul Ashok , Pandharbale Dipti Atul
Published: September 2022

The lifestyle deviations in recent past years and stress-related work regularly instigate lots of complications, like emotional and mental trauma to our body. Abusive habits like pan, gutka, supari, cigarettes add insult to it. Consequences in the release of free radicles triggering oxidative damage to cells. Leading to various diseases and disorders. Antioxidants are regularly found in many food products like leafy vegetables and fruits. Antioxidants are capable of stabilizing or deactivating, free radicals beforehand they attack cells. Antioxidants are critical for preserving optimal cellular and systemic health and well-being. High intakes of antioxidant nutrients from food sources appear to offer some health advantages. It is valuable to eat a wide variety of cereals, fruits, and vegetables rather than taking only these supplements.
Evaluation of anthropometric indices in patients with maxillomandibular fractures undergoing intermaxillary fixation
Authors: Simon Deepti , Badarunneesa .M  , Ajithkumar. K  , Manoj. S
Published: September 2022

Intermaxillary fixation affects the anthropometric measurements like body mass index (BMI) and skin fold thickness with possible changes in lipid and total protein profile while promoting loss of water, protein and fat. This study aims to determine the effect of IMF on BMI and skinfold thickness. Changes in the physiological levels of total protein, albumin, lipid profile factors and calcium were also assessed. It was a cross sectional study in patients with maxillomandibular fractures conducted at the Department of Oral and Maxillofacial Surgery, Government Dental College, Thiruvananthapuram, Kerala, India. BMI and skinfold thickness was recorded before and after the 4-week IMF period in 45 patients. SPSS software version 20.0 was used. Categorical and quantitative variables were expressed as frequency and mean +/- SD respectively. Paired t test was used on certain quantitative parameters. p < 0.05 was considered significant. This study showed that treatment with IMF can lead to changes in anthropometric indices namely BMI and skin fold thickness and possible change in total protein and albumin.
Toluidine blue: As an adjuvant screening tool
Authors: Sheikh Rayees Ahmad , Chalkoo Altaf Hussain , Wani Bashir Ahmad
Published: September 2022

Early detection and preventing the progression of potentially malignant disorders (PMDs) help in decreasing the incidence and improving the survival of those who develop oral cancer. The content of DNA and RNA is more in dysplasia and in situ carcinoma than the normal surrounding oral epithelium, the use of in vivo staining, by means of toluidine blue dye, is based on the fact that it is an acidophilic dye that selectively stains acidic tissue components such as DNA and RNA. Toluidine blue staining is considered to be sensitive in identifying early oral and oropharyngeal premalignant and malignant lesions. The results of the clinical evaluation, the toluidine blue test and histology, were compared in order to calculate the sensitivity (true-positivity) and specificity (true-negatives). According to the clinical examination, sensitivity was 53% while for toluidine blue staining, it reached 88.4% (p = 0.0007). Specificity was 76% for the clinical examination and 73.6% for toluidine blue staining (p = 0.79). The positive predictive value for clinical examination was 78.9% and 82% for toluidine blue staining (p = 0.85). The negative predictive value for clinical examination was 50% and 82.3% for toluidine blue staining (p = 0.0073). Our observations suggest that toluidine blue can act as a helpful adjuvant for biopsy in clinically suspicious lesions. So that toluidine blue negative lesions need not to be subjected to biopsies thus saving time and resourses. We conclude, toluidine blue stain could be a useful aid for clinically suspicious lesions in order to establish whether the lesions are at high risk of progression to malignancy and to contribute to an early diagnosis of oral and oropharyngeal cancer. Further studies with larger sample sizes have to be done to make the use of toluidine blue more widespread.
Estimation of blood loss in maxillofacial surgery
Authors: Dhanush C V  , Azeez Mohammed Idris , Menon Suresh , Sham Etiah , Vishwas M  Karthik , Kumar Veerendra
Published: September 2022

The maintenance of the fluid balance of surgical patients is one of the most important responsibilities of the modern surgical team and the proper replacement of blood is perhaps one of the most important phases of this maintenance Although most surgeons and anaesthesiologists well appreciate this fact, they are often faced with the problem of accurately estimating blood loss in order to avoid under-replacement or over-replacement, both of which can have adverse effects in compromised patients.

A total number of 50 subjects, both males and females in the age group of 15-50 years who reported to our centre for major surgical procedures under maxillofacial surgery were included in the study. The study was conducted between September 2012 to November 2014.

: The intraoperative blood loss in various oral and maxillofacial surgeries ranged from 63.6 – 1343 ml. 15 had 101-200 ml, 5 patients had 301-500 ml and 12 had >500 ml of blood loss. The average intraoperative blood loss in various oral and maxillofacial surgeries was 343.3 ± 256.3 ml.

: The necessity of replacement of blood depends on the amount of blood loss peri-operatively. In order to have optimal effects, the blood must be administered as it is being lost and in proper amounts. In this study Gravimetric method was used for estimation of blood loss. The gravimetric method offers the surgical team a simple and practical means of estimating the amount of blood loss during the surgery. It will also help in having an analytical idea about the average blood loss and mean reduction in haemoglobin percentage in the various oral and maxillofacial surgeries which will be helpful in evaluating the postoperative necessity of blood transfusion.

Therefore there are very few instances where blood replacement is warranted in majority of the cases of that were operated.