bluuebunny/crossref_metadata_2025 huggingface dataset:
Epidermal Growth Factor and Adenosine Triphosphate Induce Natrium Iodide Symporter Expression in Breast Cancer Cell Lines
Authors: Elliyanti Aisyah , Putra Andani Eka , Sribudiani Yunia , Noormartany Noormartany , Masjhur Johan S. , Achmad Tri Hanggono , Dachriyanus Dachriyanus
Published: August 2019

AIM: This study aims to investigate the effect of ATP, EGF and combination of those two to the Natrium Iodide Symporter (NIS) expression in MCF7, SKBR3 and HaCaT cell lines.
METHODS: MCF7, SKBR3 and HaCaT cell lines were treated with ATP, EGF and combination of those two for 6, 12 and 24 hours. The expression of NIS mRNA was measured through quantitative-reverse transcription-polymerase chain reaction (qRT-PCR). The NIS protein expression was confirmed by immunocytofluorescence.
RESULTS: NIS mRNA was expressed in SKBR3 and HaCaT cell lines but not in MCF7. The levels of NIS mRNA expression, after treatment by epidermal growth factor (EGF), adenosine Tri-Phosphate (ATP) or the combination of both for 6 and 12 hours were not significantly different from those of untreated cells. However, the treatment by a combination of ATP and EGF for 24 hours increases the level of NIS mRNA expression by 1.6 fold higher than that of the untreated cells (1.6241 ± 0.3, p < 0.05) and protein NIS expression increase significantly by the treatment than untreated cells (P < 0.05).
CONCLUSION: The level of NIS expression varies among the different subtypes of breast cancer cell lines. MCF7 cell line is representing the luminal A subtype of breast cancer does not express NIS. Only SKBR3 cell line express NIS and this subtype might be suitable to receive radioiodine therapy as those cells expressing NIS. A combination treatment of EGF and ATP increases the expression of NIS mRNA and protein at the membrane in SKBR3 cells.
Exploring the convergence between international accreditation strategy and ethics, corporate social responsibility & sustainability commitment. A case study from a French business school
Authors: Bruna Maria Giuseppina , Smith Jamie , Ben Lahouel Béchir
Published: August 2019

Cet article se propose d’étudier les dynamiques de convergence entre les stratégies d’accréditation internationale des Business Schools (induites par les pressions institutionnelles), d’une part et les démarches engagées par les Grandes Ecoles en matière d’Ethique, de Responsabilité Sociétale et de Développement Durable (ERD), d’autre part. En mobilisant la théorie de la légitimité suchmanienne au moyen de ses trois dynamiques (i.e. morale, pragmatique et cognitive), cette recherche explore la manière dont les normes d’accréditation et les politiques ERD s’influencent mutuellement. Pour ce faire, elle adopte deux perspectives : téléologique et axiologique. Fondé sur un cas d’étude, le présent article propose, en outre, une illustration empirique du chevauchement, de l’enchâssement et de l’entrecroisement entre les stratégies d’accréditation et les politiques ERD d’une Grande Ecole française. Il présente, in fine, un agenda de recherche et propose un modèle théorique, enrichi par des tableaux de bord opérationnels, pour piloter, accompagner et évaluer le rôle de l’ERD dans les accréditations internationales des Ecoles de commerce.
Leadership existentialiste sartrien revisité : pour une approche originale
Authors: Cherré Benoît , Lemieux Nathalie
Published: August 2019

Le leadership au fil des années a adopté plusieurs formes et appellations. Autocratique, démocratique, charismatique, transformationnel et transactionnel en sont quelques exemples. Plus récemment, le leadership authentique a gagné en reconnaissance auprès des chercheurs, des consultants et des praticiens. En contrepartie, de nombreuses réflexions de la part de certains chercheurs remettent en question le sens profond du leadership authentique. Cet article s’inscrit dans ce débat qui met au défi l’hypothèse de base du vrai soi où les leaders sont invités à être authentiques, réels et vrais avec eux-mêmes. Dans cet article le concept d’authenticité en leadership est abordé à partir des théories existentialistes et plus particulièrement la perspective existentialiste sartrienne. L’intention est de donner une idée plus approfondie de la façon dont les idées et les principes existentialistes peuvent être utilisés pour revigorer et réorienter la recherche sur le leadership. Nous proposons ainsi une compréhension originale de la vision de Sartre sur les notions de liberté, d’authenticité et de bienveillance. Pour Sartre (1943), la réalité humaine prend la forme de prise de conscience de sa liberté et une manière d’être. Cette liberté est la manifestation d’une conscience qui se projette dans le futur. Ce projet d’existence a pour but de surmonter l’ambiguïté ou l’angoisse de notre état face à une situation. C’est en assumant notre liberté et ses responsabilités associées que nous nous pro-jettons dans un avenir qui fait du sens à notre existence et qui déterminera nos actions et nos décisions, et ce en fonction de nos valeurs (Sartre, 1943 et 1946). Nous transposons ces concepts sur la notion de leadership et proposons – à la suite d’autres travaux – une approche de leadership de type sartrien où éthique, projet, authenticité, liberté et bienveillance en sont les composantes. Un schéma intégrateur de notre conception du leadership existentialiste est alors proposé ; conception qui se bâtit également autour de l’interprétation de notre passé, mais surtout de notre interprétation de notre futur.
Entrepreneuriat inclusif et handicap : une exploration critique de la littérature internationale
Authors: Csanyi-Virag Veronique
Published: August 2019

La démarche inclusive préconise de nouvelles approches et postures tant au niveau sociétal qu’organisationnel pour permettre un meilleur management de la diversité. Une littérature française et anglo-saxonne a commencé à définir les contours du paradigme de l’inclusion et du management inclusif mais peu de travaux ont tenté à ce jour de réunir la notion d’entrepreneuriat et d’inclusion. En effet, comme nous avons pu le constater dans les articles anglo-saxons notamment, l’inclusion a été étudiée sous l’angle des pratiques au sein des organisations et non sous l’angle de l’entrepreneurship, du dirigeant entrepreneur développant des actions entrepreneuriales inclusives. L’inclusion représente un véritable défi organisationnel dans la continuité de la mise en œuvre des politiques de diversité. Les recherches consacrées au management de la diversité et à l’inclusion posent les difficultés liées aux pratiques et à l’opérationnalisation dans l’entreprise révélant ainsi les enjeux organisationnels et sociétaux sous-jacents. Notre recherche vise à démontrer, à partir du contexte spécifique du handicap, en quoi il devient indispensable de réinterroger et de repenser les pratiques courantes de l’entrepreneuriat. Nous poserons ce questionnement à travers une revue de la littérature francophone et anglo-saxonne. Pour cela, nous préciserons la genèse du concept d’inclusion dans le monde du handicap et ses liens étroits avec le management de la diversité avant d’appréhender le nouveau paradigme de l’entrepreneuriat inclusif proposé en matière de déterminants entrepreneuriaux : nouveaux comportements et pratiques entrepreneuriales.
L’art du patrimoine comme pont entre le centre pénitentiaire et l’école rurale : un regard interculturel
Authors: Pino-Alonso David , Sandoval Rodolfo , Cortés Natalia , Roca Ramón
Published: August 2019

Cet article porte sur les implications éducatives d’un projet de mise en valeur du patrimoine artistique dont l’objectif est de relever les principales expressions artistiques du patrimoine de la région du Maule au Chili. Celles-ci sont cultivées par des détenus et des anciens détenus d’un centre pénitentiaire de la même localité. Depuis une approche interculturelle, il est possible de comprendre ces expressions comme un mécanisme efficace de réinsertion sociale et comme un moyen de communication entre la réalité de centres pénitentiaires et des écoles placées en zones rurales : deux espaces caricaturés comme étant marginaux et, généralement, peu visibles dans des centres régionaux d’information et de culture. De cette façon, on cherche également à explorer les idées (pré) conçues des élèves autour de l’espace social pénitentiaire et le niveau de mise en valeur de leur propre patrimoine tangible à partir du regard d’un autre, situé en dehors de son espace de proximité.
La identidad lectora del docente que enseña a leer: hacia la consideración de las historias de lectura como insumos didácticos para la enseñanza
Authors: Gaete Moscoso Rosa
Published: August 2019

Cet article décrit une étude des pratiques de lecture des enseignants qui apprennent à lire, dans laquelle on a incorporé, dans le plan analytique, leurs pratiques réelles (passées et présentes) pour démontrer comment l’autoimage de l’enseignant affecte sa manière d’enseigner. Le manque de reconnaissance de ses pratiques réelles (passées et actuelles) est dû à la position de l’enseignant entre une culture légitimée (mobilisée par l’école) et la sienne (qui n’est pas nécessairement du même statut). La proposition est d’étudier la relation entre les histoires de lecture des enseignants et l’approche qu’ils ont vis-à-vis de l’enseignement de la lecture tout en pointant l’importance de reconnaître les pratiques réelles des acteurs pour enrichir et promouvoir les changements culturels dès les premières étapes de l’enseignement-apprentissage de cette compétence culturelle.
Uso de un software matemático y su incidencia en el proceso de enseñanza-aprendizaje del algebra elemental
Authors: Pizarro Rendic Luis Esteban
Published: August 2019

Cet article portant sur l’usage d’un logiciel mathématique et son incident sur le processus d’enseignement et d’apprentissage de l’algèbre élémentaire a pour but de connaître la relation entre le logiciel éducatif mathématique et l’augmentation significative de l’apprentissage, pour des élèves de première année en cursus d’ingénierie. Par ailleurs, ce travail permettra d’établir les avantages et les désavantages de son application dans l’apprentissage des étudiants dans leurs formations personnelles et intellectuelles ainsi que sa cohabitation avec l’actuelle technologie. D’un autre côté, l’intérêt constituera un facteur prépondérant afin de fournir à l’institution des laboratoires informatiques avec des logiciels éducatifs respectifs, en plus de promouvoir des actions et des moyens au service de la quotidienneté des tâches éducatives de l’enseignant.
Low Temperature Graphene Growth Effort on Corning Glass Substrate by Using VHF-IP HWC-PECVD
Authors: Yusuf Momang A. , Rosikhin Ahmad , Malago Jasruddin D. , Noor Fatimah A. , Winata Toto
Published: August 2019

One promising method for growing carbon-based materials, especially for electronics and optoelectronics application, is PECVD (Plasma Enhanced Chemical Vapor Deposition). In addition to the large-area thin film obtained, this method also requires relatively lower growth temperature. By modifying the PECVD reactor through the application of Hot-Wire Cell (HWC) placed between two electrodes (called In Plasma, IP), and plasma generator frequency of 70 MHz which is categorized as Very High Frequency (VHF), graphene flakes have been successfully grown by using methane (CH4) gas as precursor at pressure 300 mTorr and substrate temperature of 275°C on corning glass substrate. This result indicates that this method is potentially to grow graphene at lower temperature by adjusting several growth parameters, especially temperature of hot wire cell that plays important role in the deposition process. It should be noted that important factor that greatly determined the successful of graphene flakes growth was the use of metal catalyst in the form of very thin film. In this research, silver was used as metal catalyst which was prepared by evaporation method and then annealed at 600°C for 30-60 minutes.
Relationship between the Structure and Electrical Conductivity of 12-Mer Single-Stranded Polyadenine Studied by Scanning Tunnelling Microscope
Authors: Rozak Harison , Zaharim Wan Nurfadhilah , Miyazaki Issei , Ismail Nur Eliana , Abu Bakar Siti Nuramira , Kernain Daruliza , Samian Razip , Ichimura Koichi , Mohamed-Ibrahim Mohamed Ismail , Shukri Sulaiman , Watanabe Isao
Published: August 2019

Abstract: In order to investigate the structure and electrical conductivity of (DNA), Scanning Tunnelling Microscopy (STM) studies were carried out on a model of DNA which was composed of a 12-mer single-stranded polyadenine connected via sugar-phosphate backbone. The 12-mer single-stranded polyadenine molecules were found to be aligned in parallel to each other at a separation 25±7.5 Å. This alignment formed a one-dimensional chain structure, which indicated that the side-by-side coupling among the molecules was strong. The STM measurements with constant current mode and fixed bias voltage, demonstrate that, the electrical conductivity of DNA bases could be deduced by monitoring the size of the structure of 12-mer single-stranded polyadenine.
Quality Improvement of Biomaterial of Lemna Sp
Authors: Andriani Yuli , Iskandar Iskandar , Zidni Irfan , Risdiana Risdiana
Published: August 2019

The quality of biomaterial of Lemna sp. as functional material for fish feed has been improved by solid substrate fermentation method. The fermentation was performed by using 5% commercial probiotic. The content of nutrition, size and diameter particle, and functional group of Lemna sp before and after fermentation have been investigated. After fermentation, it is found that the crude protein increased from 13.22% to 18.64% and crude fiber content decreased from 20.08% to 12.45%. The average size particle and distance between particles of fermented Lemna sp meal were 193.534 μm and 573.955 μm, respectively. While the functional group did not change after fermentation, the present result indicated that fermentation process can improve the quality of biomaterial of Lemna sp as functional material for fish feed.
The Morphology of Si-K-HAs Composite Prepared by Spray Drying
Authors: Muljani Srie , Setyawan Heru , Sumada Ketut
Published: August 2019

The silica potassium humic substance (Si-K-HAs) composite have been produce by spray drying successfully. In the previous study the preparation of Si-K-HAs gel by precipitation method required the addition of acid so that Si-K-HAs gel product contains acid salts. This study was develope spray drying method in order to eliminate the use of acid. The mixture of potassium silicate, cellulose and humic potassium solution was mixed with varying volume ratios and flowed into a spray dryer to produce Si-K-HAs powder. The used of cellulose (CMC) in this study acts as a homogeneous agent so that silica and humic substance can be completely mixed at controlled viscosity. Si-K-HAs products were characterized by Scanning electron microscopy (SEM), X-ray fluorescence (XRF), X-ray diffraction (XRD), Fourier transform infrared spectrometry (FTIR), and Surface area analytical (SAA). The result showed that the Si-K-HAs composite prepared by spray dryers have spherical particles, SiO2 in the range of 48-50%, K2O in the range of 49-50%. The present of cellulose caused the increasing of Si-K-HAs particle size e.g 17.30 μm prepared without CMC to 41.11 μm prepared with addition of 100g of CMC. The presence of cellulose can also increase the surface area of the spray-dried Si-K-HAs particles from 111.92 m2g-1; 163.241 m2g-1.
Synthesis of Precipitate Calcium Carbonate with Variation Morphology from Limestone by Using Solution Mixing Method
Authors: Arifin Zaenal , Triwikantoro Triwikantoro , Subagyo Bintoro Anang , Zainuri Mochammad , Darminto Darminto
Published: August 2019

Abstract. In this study, the CaCO3 powder has been successfully synthesized by mixing CaCl2 from natural limestone and Na2CO3 in the same molar ratio. The mixing process of solutions was carried out by employing the molar contents of 0.125, 0.25, 0.375 and 0.5M at varying temperatures of 30, 40, 60 and 80ᴼC. The produced CaCO3 microparticles were characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The highest content of aragonite phase with morphology rod-like of the samples is around 29 wt%, resulting from the process using solution of 0.125 M at 80 ᴼC. While at 30 ᴼC and 40 ᴼC produced 100 wt% calcite phase.
Solvent Effect on Bond Dissociation Enthalpy (BDE) of Tetrahydrocurcumin: A Theoretical Study
Authors: Boli Lusia Silfia Pulo , Aisyah Nufida Dwi , Khoirunisa Vera , Rachmawati Heni , Dipojono Hermawan Kresno , Rusydi Febdian
Published: August 2019

Solvent effect on bond dissociation enthalpy (BDE) of different functional groups of tetrahydrocurcumin is investigated. This is to evaluate how the polarity of a medium affect BDE and to clarify which functional groups hold the key role in its antioxidant activity through hydrogen transfer. We occupy density functional theory to calculate BDE through geometrical optimization and frequency calculation at six sites of tetrahydrocurcumin in water, methanol and chloroform solvents. The solvents represent polar and non-polar medium. Our result shows that BDE is lower in non-polar medium and hydrogen transfer is favored in this medium. A phenolic group is responsible for the antioxidant activity of tetrahydrocurcumin.
Predicting Notable Radical Scavenging Sites of Gnetin C Using Density Functional Theory
Authors: Khoirunisa Vera , Boli Lusia Silfia Pulo , Nur Fadilla Rizka , Saputro Adhitya Gandaryus , Rachmawati Heni , Dipojono Hermawan Kresno , Rusydi Febdian
Published: August 2019

We have been investigating the scavenging activity of gnetin C theoretically in the molecular level. In this work, we perform density functional based calculations to predict the possible site of gnetin C for free radical scavenging activity. The water solvent effect is considered as polarizable continuum model. All possible scavenging sites have been evaluated by obtaining the bond dissociation enthalpy (BDE) for one hydrogen atom abstraction. The results demonstrate that O-H bonds generally have lower BDE relative to C-H bonds of gnetin C. We also find that C-H bonds in 5-membered heterocyclic ring have exceptionally lower BDE. This could be additional possible sites for gnetin C to scavenge more free radicals in addition to hydroxyl groups.
Synthesis and Characterization of Magnetic Rubidium Superoxide, RbO2
Authors: Astuti Fahmi , Miyajima Mizuki , Fukuda Takahito , Kodani Masashi , Nakano Takehito , Kambe Takashi , Watanabe Isao
Published: August 2019

Polycrystalline rubidium superoxide (RbO2) has been synthesized by using solution method followed by the reaction process under the cooling condition of-40 °C. X-ray Powder Diffraction (XRD) spectra showed that RbO2 was successfully synthesized by this method. The magnetic susceptibility and pulsed muon spin relaxation (μSR) measurements were carried out in order to study the magnetic properties of RbO2.
Magnetic Properties of Hole-Doped Pyrochlore Iridate (Y1-x-yCuxCay)2Ir2O7
Authors: Angel Julia , Asih Retno , Nomura Hironori , Taniguchi Tomoya , Matsuhira Kazuyuki , Ramadhan Muhammad Redo , Ramli Irwan , Wakeshima Makoto , Hinatsu Yukio , Mohamed-Ibrahim Mohamed Ismail , Shukri Sulaiman , Watanabe Isao
Published: August 2019

We report the results of studies on the electronic state of the hole-doped Y-based pyrochlore iridate, (Y1-x-yCuxCay)2Ir2O7. We carried out the resistivity, Muon Spin Relaxation (μSR), X-ray Photoemission Spectroscopy (XPS) measurements and Density Functional Theory (DFT) calculations on the non-doped (x=y=0) and doped (x=0.05, y=0.15) systems. We found in the non-doped system that the magnetic ordering of Ir spins which was accompanied by the metal-insulator transition (MIT) occurred at around 157 K and disappeared in the doped system in which MIT seems to disappear or smeared out. We suggest from the current study that a quantum critical point which shows a change in the electronic ground state from insulating to metallic to exist between those two systems.
Preparation of Local Raw Material for α-Fe2O3 Nanoparticles Powder from Mineral Extraction of Iron Sand
Authors: Izaak Maya Puspitasari , Sitompul Henni , Wisnu Ari Adi , Gunanto Yohanes Edi
Published: August 2019

Synthesis and characterization of α-Fe2O3 nanoparticles were obtained from extraction of ilmenite iron sand with coprecipitation method and to obtain α-Fe2O3 nanoparticles, high energy milling (HEM) was used. Surface morphology and identification of the elements contained in the sample were analyzed using scanning electron microscope (SEM) and energy dispersive spectroscopy (EDS). For phase analysis and crystal structure, X-ray diffractometer (XRD) was used. Moreover a vibrating magnetometer sample (VSM) was used to characterize its magnetic properties, while tunneling electron microscopy (TEM) was used for particle size characterization. Ilmenite-type iron sand has a diverse particle shape with a size of more than 100 μm with ilmenite (FeTiO3) mineral content of about 64.7%. The results of extraction using coprecipitation method with sintering 750 °C, obtained hematite α-Fe2O3 material which has not been saturated to an external magnetic field of 1 tesla, the magnetic remanent value (Mr) is about 0.8 emu/g and the coercivity field value is Hc around 773 Oe. The average size of hematite α-Fe2O3 particles after being milled 50 hours is between 15-30 nm with a cube-like shape.
Crystal Structure and Magnetic Properties of Non-Stoichiometric Co2MnGa Heusler Alloy
Authors: Pandu Akbar Mochammad Yan , Sihombing Rombang Rizki , Sakai Akito , Nugroho Agustinus Agung , Nakatsuji Satoru
Published: August 2019

Crystal structure and magnetic properties of Heusler-alloy Co2MnGa were examined systematically using non-stoichiometric compositions of Co and Mn element from the Czochralski as-grown single crystal samples. The crystalline structure of each sample was characterized by means of X-ray powder diffraction technique. Each sample was treated with and without heat treatment at 923 K for 10 hours. The effects of Co and Mn excess were observed in the lattice constants for both treatments. The L21-type crystal structure was observed only for the heat-treated samples. The changes in lattice constants are attributed to the substitution of atomic sites. The excess of Co tends to decrease the crystal volume, in opposite to the excess of Mn. In order to investigate the Slater-Pauling rule in the non-stoichiometric samples, the saturation magnetic moments were measured from the field-dependent magnetization measurement for the as-grown samples at 2 K. The deviation from the Slater-Pauling rule was found in the lower concentration of valence electron which associated to the lower total fraction of both Co and Mn. This indicates that the magnetic interactions of these materials cannot only be contributed to the number of valence electron.
Analysis of Defects and Surface Roughness on the Hydrogenated Amorphous Silicon (a-Si:H) Intrinsic Thin Film for Solar Cells
Authors: Cahyono Yoyok , Dwi Purnamasari Novita , Zainuri Mochammad , Pratapa Suminar , Darminto Darminto
Published: August 2019

Effect of defect - through observation of energy absorption Urbach, on deposition rate, energy band gap, and surface roughness of intrinsic thin film are investigated using Radio Frequency Plasma Enhance Chemical Vapor Deposition (RF-PECVD). Films are grown on ITO (Indium Tin Oxide) glass substrate. Analysis of energy band gap is conducted to determine changes in the structure of a thin film of a-Si:H. Energy band gap is important to determine the portion of the spectrum of sunlight that is absorbed solar cells. From the characterization using UV-Vis spectrometer and the Tauc’s plot method, the width of the resulting energy band gap is greater if the hydrogen dilution is increased. It can be shown that the increase of the hydrogen dilution, will increase the energy band gap, and the surface roughness of thin layers. Instead, the improvement of the hydrogen dilution decrease the rate of deposition and Urbach energy. It is estimated that with greater hydrogen dilution, an intrinsic thin film of a-Si:H is more conductive for more reduction in residual of band tail defects or dangling bond defects.
Geopolimer Concrete for Radiation Shielding Application
Authors: Nurhasmi Nurhasmi , Tahir Dahlang , Abdullah Bualkar , Ansar Asnaeni , Ilyas Sultan , Mutmainna Inayatul , Madda Wawan Indrawan
Published: August 2019

Abstract. Ashield of gamma radiation with a basic material of fly ash (FA) type C have been made by additional graphite (G) and Fe2O3 (F) using Retsch MM 400 for 30 minutes at the frequency 10 Hz. GF is added to the FA matrix with mass variations of 0%, 1%, 2%, and 3%. Samples were activated with alkali solution at 70°C. Density obtained by calculation of each sample FA_GF0, FA_GF1, FA_GF2, and FA_GF3 are 2.09 g/cm-3, 2.111 g/cm-3, 2.113 g/cm- 3, and 2.115 g/cm-3, respectively. For sample FA_GF3 the density is high but the attenuation coefficient is small. This is influenced by the presence of graphite content in the sample. Graphite also plays a role in forming pores caused the radiation more transmitting through the samples. It can be concluded that the very good composition of the additional of GF is 2% with half value layer (HVL) is 3.980 cm and mean free path (MFP) is 5.743 cm.
Synthesis and Characterization of Supercapacitor Electrode from Fiber of Borassus flabelifer L by Activation Method
Authors: Prasetya Fandi Angga , Anggarini Ufafa , Zakaria Yudha , Putri Rosa Dwi Sasqia
Published: August 2019

Supercapacitor require electrode which has high surface area so that it able to store large amounts of charge. In this study, electrode was synthesized from carbon of Borassus Flabellifer L fiber which was carried out through activation and carbonization processes. Raw material was calcined at 400°C for 4 hours followed by activation with NaOH 1 M. The carbonization was then conducted in Nitrogen gas flowing by temperature variations; 650°C, 750°C, and 850°C with a constant heating rate of 20 °C/min. Based on XRD data, it was shown that the material has formed Reduced graphene Oxide (RGO) which has main peaks at (2θ) 240 and 440 with higher purity in higher temperature. SEM results clarified more pores formation at higher temperature which is mesoporous. Cyclic Voltammetry (CV) test was done to determine the capacitance value. By RGO forming with high porosity, it is suitable for supercapacitor electrode application and CV test has examined that heating of Borassus Flabelifer L fiber at 850°C with 5 mV/s scan rate has the highest specific capacitance by 8.25 F/gram with Energy density is 4.125 watt/gram.
An Approach to the Intermediate State of the Distributed Internal Fields on Muon Site
Authors: Umar Muhamad Darwis , Watanabe Isao
Published: August 2019

We show a new approach to provide anaysis functions of the muon-spin depolarization in order to describe the intermediate state between Gaussian and Lorentzian behavior. The Kubo Golden Rule (KGR) formula was used to mix the Gaussian and Lorentzian probability density functions. The result confirmed that the KGR formula can analytically explain the intermediate states. The current study suggests a new approach to investigate the so-called pseudogap state of high-Tc superconducting oxides.
Crystal Structure and Electrical Properties of (1-x) (Ba0.85Sr0.15)TiO3 - x(K0.5Na0.5)NbO3 System
Authors: Nuraini Umi , Kaukaba Yhuanita Nurul , Mashuri Mashuri , Suasmoro Suasmoro
Published: August 2019

The composition of (1-x) (Ba0.85Sr0.15)TiO3 – x (K0.5Na0.5)NbO3 (BST-KNN) for x=0.1 and x=0.2 were successfully prepared by two separate synthesis namely oxalate co-precipitation (for BST) and solid-state reaction (for KNN). Sintered pellet at 1200 °C for 2h exhibits a single phase except x= 0.2 showing a secondary phase and was identified as Ba2TiO4. KNN doped BST system show tetragonal symmetry in which higher dopant expand its tetragonality (c/a). The density of sintered samples deduced by Archimedes method are slightly higher than 90%. Permittivity measurements as function of temperature show almost similar Tc= 90 °C at frequency 1.273 kHz and shift to higher temperature as frequency increases indicating a typical relaxor characteristics. At room temperature the relative permittivity showing Debye relaxation characteristic with ωr=12560 (x=0.1) and ωr =20096 (x-0.2). Furthermore, as function of temperature the activation energy deduced from relaxation time was obtained Ea=0,564 eV for x=0.1 and 0,58 eV for x=0.2.
Therapeutic effects of iNOS inhibition against vitiligo in an animal model
Authors: Mansourpour Hamid , Ziari Katayoun , Kalantar Motamedi Sahar , Hassan Poor Amin
Published: August 2019

Nitric oxide (NO) is involved in several biological processes, but its role in human melanogenesis and vitiligo need further studies. Previous studies revealed that exposure to UVA and UVB were capable of the inducing nitric oxide production in keratinocytes and melanocytes through the activation of constitutive nitric oxide synthase, whereas inducible nitric oxide synthase overexpression has been reported to play an important role in hyperpigmentary disorders. The aim of this study was to evaluate iNOS inhibitor aminoguanidine (AG) as a therapeutic agent in our mouse model of vitiligo. In this study, male C57BL/6J Ler-vit/vit mice were purchased to evaluate the effect of iNOS inhibitor (aminoguanidine) (50 and 100 mg/kg) and L-arginine (100 mg/kg) in a mouse model of vitiligo induced by monobenzone 40%. Moreover, we used phototherapy device to treat the mice with NBUVB as a gold standard.The findings revealed that monobenzone was capable of inducing depigmentation after 6 weeks. However, aminoguanidine in combination with monobenzone was decrease the effect of monobenzone, while L-arginine play a key role in promoting the effect of monobenzone (P<0.001). Based on the phototherapy, the efficacy of phototherapy significantly increased by adding L-arginine (P<0.05). Taken together, we suggest that iNOS inhibitor can be a novel treatment for the prevention and treatment of vitiligo by combination of NBUVB therapy, furthermore; NO agents like L-arginine could also increase the effectiveness of phototherapy. Taken together, this pilot study showed significant repigmentation of vitiligous lesions treated with iNOS inhibitor plus NBUVB therapy, where other aspect including expression of an inducible iNOS, NO and TNF levels remained to be evaluated in mice model.
Shrinking risk profiles after deworming of children in Port Elizabeth, South Africa, with special reference to Ascaris lumbricoides and Trichuris trichiura
Authors: Müller Ivan , Gall Stefanie , Beyleveld Lindsey , Gerber Markus , Pühse Uwe , Du Randt Rosa , Steinmann Peter , Zondie Leyli , Walter Cheryl , Utzinger Jürg
Published: August 2019

Risk maps facilitate discussion among different stakeholders and provide a tool for spatial targeting of health interventions. We present maps documenting shrinking risk profiles after deworming with respect to soil-transmitted helminthiasis among schoolchildren from disadvantaged neighbourhoods in Port Elizabeth, South Africa. Children were examined for soil-transmitted helminth infections using duplicate Kato-Katz thick smears in March 2015, October 2015 and May 2016, and subsequently treated with albendazole after each survey. The mean infection intensities for Ascaris lumbricoides were 9,554 eggs per gram of stool (EPG) in March 2015, 4,317 EPG in October 2015 and 1,684 EPG in March 2016. The corresponding figures for Trichuris trichiura were 664 EPG, 331 EPG and 87 EPG. Repeated deworming shrank the risk of soil-transmitted helminthiasis, but should be complemented by other public health measures.
Core-Muscle Training and Neuromuscular Control of the Lower Limb and Trunk
Authors: Sasaki Shizuka , Tsuda Eiichi , Yamamoto Yuji , Maeda Shugo , Kimura Yuka , Fujita Yuki , Ishibashi Yasuyuki
Published: August 2019

Context

Comprehensive injury-prevention training (plyometric, agility, balance, and core-stability exercises) has been shown to decrease sport-related injury. The relationship between trunk control and sport-related injury has been emphasized; however, the isolated effects of core-muscle training are unclear.

Objective

To investigate the effect of a simple 8-week core-muscle–training program on the neuromuscular control of the lower limb and trunk during jump landing and single-legged squatting.

Design

Controlled laboratory study.

Setting

Laboratory.

Patients or Other Participants

Seventeen female collegiate basketball players were randomly divided into training (n = 9; age = 19.7 ± 0.9 years) and control (n = 8; age = 20.3 ± 2.5 years) groups.

Intervention(s)

The training group completed the core-muscle–training program in addition to daily practice, and the control group performed only daily practice. Kinematic and kinetic data during a drop-jump test and single-legged squat were acquired using a 3-dimensional motion-analysis system.

Main Outcome Measure(s)

Three-dimensional hip, knee, and trunk kinematics; knee kinetics; and isokinetic muscle strength were measured at the pretraining and posttraining phases.

Results

For the drop-jump test, the maximal trunk-flexion angle increased (P = .008), and peak knee-valgus moment (P = .008) decreased in the training group. For the single-legged squat, the peak trunk-flexion angle increased (P = .04), and the total amount of trunk lateral-inclination angle (P = .02) and peak knee-valgus moment (P = .008) decreased in the training group. We observed no changes in the control group.

Conclusions

A consecutive 8-week core-muscle–training program improved lower limb and trunk biomechanics. These altered biomechanical patterns could be favorable to preventing sport-related injuries.
Devising a development test of auditory perception: Problems and prospects
Authors: Abramovitz Arnold
Published: August 2019

It is certain that many children whose auditory perception is queried by audiologists, speech therapists, educationists and psychologists elude the diagnostic screens presently available in each of these disciplines. The need for a qualitative and quantitative psychological assessment of the child's auditory abilities and disabilities led to the development of a test which was intended to evaluate the following functions:(a) Recognition of environmental sounds, (b) Auditory figure-ground discrimination, (c) Speech-sound discrimination (phonemic and intonational) and (d) Tonal pattern discrimination (pitch, loudness, duration and interval). It was not intended to investigate threshold phenomena as such but rather to supplement and complement pure-tone and speech audiometry. The test was applied to 205 children, aged five to ten years, drawn from a normal school population, and 232 children with difficulties and handicaps varying both in degree and kind. Only the first two sub-tests were found to be clinically and experimentally viable, and data for the curtailed test are presented. The following results are noteworthy: (1) The test measures functions which are positively related to both age and intelligence. (2) Brain-injured, retarded and emotionally disturbed children generally test low on auditory figure-ground discrimination; this vulnerability is most likely due to perseveration. (3) Previously unsuspected peripheral hearing losses may sometimes be detected by the use of the test. On the other hand, some children said to have high degrees of hearing loss test at or above their age-level. (4) Many deaf and hard-of-hearing children test higher without their hearing-aids; this is probably due to amplification being achieved at the cost of distortion. (5) Children of average intelligence with reading and/or spelling difficulties often test low on auditory figure-ground discrimination. (6) Blind children who have received auditory training are equal to sighted children in recognition of environmental sounds, but superior in auditory figure-ground discrimination. This does not, however, necessarily signify superior auditory perception as such on the part of the blind. In general it is concluded that the development of tests of auditory perception could add significantly to the psycho-educational assessment of both "normal" and handicapped children.
Operation of the auditory feedback monitoring loop in children with articulatory defects
Authors: Ossip Sandra
Published: August 2019

This study constitutes a preliminary evaluation of the utilization of auditory feedback for the acquisition of normal speech in normal speaking children and children having functional articulatory errors. The degree to which this is utilized for the organization and control of motor activity was inferred by delaying auditory feedback in time and quantitating the resulting disturbances in the speech behaviour. Evidence was found to support the following hypotheses: I. There is a breakdown of speech under DAF. 2: Children with multiple articulatory disorders exhibit less severe breakdown effects under DAF than their normal peers. 3. There appears to be a strong relationship between increasing age and articulatory ability. 4. There tends to be a relationship between increasing age and the breakdown of speech under DAF. 5. Monitoring of speech is a highly skilled control system which tends to develop with age and experience, and is not operating as strongly in the child with articulation-defects. From the results of the study, it seems that the auditory feedback monitoring loop for speech is not operating as successfully in the child with multiple articulatory errors as it operates in the normal child, and that the development of a closed loop system appears to be retarded in some way.
Die gebruik van die akoestiese refleks vir bepaling van die gehoorapparaat winsinstelling
Authors: Basson Marina
Published: August 2019

Spraakdiskriminasieinstellings is van twaalf gehoorapparaatdraers met sensories-neurale gehoorverliese verkry. Die toetsstimuli was Afrikaanse eenlettergrepige woorde wat in die teenwoordigheid van agtergrondsgeraas van aaneenlopende spraak met 'n sein-tot-ruis verhouding van +10dB aangebied is. Spraakdiskriminasieinstellings  is by vier winsinstellings vir elke proefpersoon gemaak, naamlik: 'n winsinstelling wat die akoestiese refleksdrempel vir spraakgeraas ontlok in die oor kontralateraal tot die oor met die gehoorapparaat; twee winsinstellings by +/- 10dB relatief tot die refleks drempel winsinstelling; en 'n winsinstelling waar aaneenlopende spraak teen 50dB gehoorpeil vir die pasiënt mees gemaklik klink. Die hoogste gemiddelde spraakdiskriminasietelling is by die refleksdrempel winsinstelling verkry.
'n Ondersoek na die vokaalduur van die esofagale Afrikaanssprekende
Authors: Botha Mariette
Published: August 2019

In hierdie studie is daar 'n ondersoek gedoen na die ooreenkoms wat daar bestaan tussen die vokaalduur van die normaalsprekendes en die vokaalduur van die esofagale sprekers. Daar is gepoog om die verband tussen spraakvaardigheid en vokaalduur van die esofagale sprekers te bepaal. Bykomend is die verband tussend die vokaal- plus postvokaalduur en die spraakvaardigheid en vokaalduur van die esofagale sprekers te bepaal. Die invloed van die stemhebbenheid/stemloosheid van die konsonantomgewing op die vokaalduur is ook vasgestel.Dit blyk uit die resultate dat die lengte ten opsigte van die vokaalduur by die groep esofagale sprekers wisselend was, maar in gevalle het dit ook oreengestem met die normaalsprekende. Ondersoeke kon nie 'n beduidenaantoonbare verband tussen vokaalduur en spraakvaardigheid vasstel nie, hoewel daar 'n meer aantoonbare verband tussen vokaal plus postvokaalduur en spraakvaardigheid is. Die duur van die vokale in die stemhebbend-stemlose konsonantomgewings by die esofagale sprekers was hoofsaaklik langer as die duur van hierdie vokale in die stemloos-stemlose konsonantomgewings, soos by die normaalsprekendes.
Associations of visceral fat thickness and anthropometric measurements with non-alcoholic fatty liver disease development in male patients mono-infected with human immunodeficiency virus
Authors: Vujanović Miloš , Brkić-Jovanović Nina , Ilić Dalibor , Drvendžija Zorka , Srdić-Galić Biljana , Turkulov Vesna , Brkić Snežana , Marić Daniela
Published: August 2019

Background: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease in mono-infected (without concomitant hepatitis B and/or C virus infection) people living with human immunodeficiency virus (HIV). The proper and on time identification of at-risk HIV-positive individuals would be relevant in order to reduce the rate of progression from NAFLD into non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma.Objectives: The aim of this study was to explore visceral fat thickness (VFT) and anthropometric measurements associated with the development of NAFLD in patients mono-infected with HIV and on long-standing combination antiretroviral therapy (cART).Method: Eighty-eight (n = 88) HIV-positive male patients, average age 39.94 ± 9.91 years, and stable on cART, were included in this prospective study. VFT was measured using ultrasonography. Anthropometric measurements included body mass index (BMI), waist-to-hip ratio (W/H), waist-to-height ratio (WHtR), waist and hip circumference (WC, HC). Differences between variables were determined using the chi-square test. The receiver operating characteristic (ROC) curve and the Youden index were used to determine optimal cut-off values of VFT and hepatic steatosis. The area under the curve (AUC), 95% confidence intervals, sensitivity and specificity are reported for the complete sample. Significance was set at p < 0.05.Results: Patients with steatosis had significantly higher values of BMI, HC, WC, W/H and WHtR. The VFT was higher in patients with steatosis (p < 0.001). Specifically, VFT values above 31.98 mm and age > 38.5 years correlated with steatosis in HIV-positive patients, namely sensitivity 89%, specificity 72%, AUC 0.84 (95% CI, 0.76–0.93, p < 0.001), with the highest Youden index = 0.61. The sensitivity of the age determinant above this cut-off point was 84%, specificity 73% and AUC 0.83 (95% CI, 0.75–0.92, p < 0.001), with the highest Youden index of 0.57.Conclusion: In the absence of more advanced radiographic and histological tools, simple anthropometric measurements and VFT could assist in the early identification of persons at risk of hepatic steatosis in low- and middle-income regions.
The accuracy of extended-spectrum beta-lactamase detection in Escherichia coli and Klebsiella pneumoniae in South African laboratories using the Vitek 2 Gram-negative susceptibility card AST-N255
Authors: Young Andrea L. , Nicol Mark P. , Moodley Clinton , Bamford Colleen M.
Published: August 2019

Background: Phenotypic detection of extended-spectrum beta-lactamases (ESBLs) is based on the inhibition of ESBL enzymes by β-lactamase inhibitors and on the comparison of cephalosporin activity with or without a β-lactamase inhibitor. Many South African diagnostic laboratories rely on the Vitek 2 for automated susceptibility testing and for ESBL detection. However, the Gram-negative susceptibility card currently used locally (AST-N255) has been modified and its accuracy for ESBL detection is not known.Methods: We randomly selected 50 isolates of Klebsiella pneumoniae and Escherichia coli from a collection of clinical bloodstream isolates from Groote Schuur Hospital from 2015 to 2016, including ESBL-producing and non-ESBL-producing strains. We used standardised phenotypic (disc diffusion and broth microdilution) and genotypic (conventional polymerase chain reaction (PCR) for blaCTX-M, blaSHV and blaTEM) methods for detection of ESBLs. We compared ESBL detection by Vitek 2 to a composite reference standard comprising ESBL detection either by both phenotypic methods or by one phenotypic method together with genotypic detection.Results: The sensitivity of Vitek 2 system for detection of ESBLs was 33/36 or 92% (78% – 97%) for E. coli, and 40/40 or 100% (91% – 100%) for K. pneumoniae, whilst specificity was 10/10 or 100% (72% – 100%) and 9/10 or 90% (60% – 98%), respectively. This is comparable with previous studies.Conclusion: Using a composite reference standard of the phenotypic and genotypic methods employed in this study, no Vitek-categorised ESBL E. coli or K. pneumoniae was found to be a non-ESBL with the exception of possible misinterpretation with K. pneumoniae SHV-hyper-producing isolates.
Radiological management of skeletal metastases, multiple myeloma and lymphoma
Authors: Reiser Maximilian F.
Published: August 2019

No abstract available.
Lung cancer screening using low-dose CT
Authors: Greniér Philippe
Published: August 2019

No abstract available.
Tips for the Radiologist: Catheter-induced arterial spasm and standing waves
Authors: Duncan Ian C.
Published: August 2019

No abstract available.
Is routine abdominal radiography of any value prior to an abdominal ultrasound investigation?
Authors: Nel B. , Scher A. T.
Published: August 2019

It is common practice to do a routine abdominal X-ray prior to doing an abdominal ultrasound investigation. This study questioned the value of the abdominal film to determine whether it should be mandatory. In this prospective, descriptive clinical study at Tygerberg Hospital, a tertiary referral hospital, we included 100 consecutive patients referred to the Ultrasound Department for an abdominal ultrasound, for a variety of indications.An ultrasound of the abdomen was performed and the abdominal film evaluated for each patient. The examinations were performed within 24 hours of each other. The abnormalities were observed and the ultrasound and X-ray diagnoses recorded. The abdominal film played a vital role in ultrasound diagnosis in only 2% of patients, while in 8% it played a positive role.
Pituitary prolactinoma with amyloid deposits: Surgery or dopamine agonists? Review of previous reports and new recommendations for management
Authors: Prabhu Santosh , Prabhu Sujata
Published: August 2019

Background: Pituitary adenomas, macro and micro, are a common occurrence in most neurosurgical centers. Prolactinomas are the most common pituitary tumors and are often treated nowadays with dopamine agonists such as cabergoline, with good results. Aims and Objectives: To suggest new therapeutic guidelines for treating Prolactinomas with Amyloid deposits on preoperative detection of Amyloid deposition in Pituitary tumors, based on MRI characteristics. Materials and Methods: We report a case of a pituitary prolactinoma with amyloid deposits in a 45-year-old male who underwent a transsphenoidal excision of the adenoma. Although on magnetic resonance imaging scans, no amyloid was reported, at histopathology, spherical amyloid within the pituitary tumor was found in abundance. The patient underwent surgery without any trial of cabergoline due to rapid deterioration of vision. Conclusion: Prolactinomas with amyloid deposits are known not to respond to dopamine agonists (cabergoline) by a reduction in size and may ,in fact increase in volume. Therefore, we recommend that in prolactinomas not responding to medical therapy, deposition of amyloid has to be considered as a cause for failure of medical therapy and surgery and then has to be offered pronto.