bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemodelan Struktur Bawah Permukaan Berdasarkan Data Mikrotremor di Kecamatan Kampung Melayu, Kota Bengkulu
Authors: Hutasoit Tegar Ashary , Refrizon Refrizon , Suhendra Suhendra
Published: February 2025

Kecamatan Kampung Melayu, Kota Bengkulu, mengalami pertumbuhan infrastruktur yang pesat, sehingga memerlukan mitigasi bencana sejak dini. Penelitian ini bertujuan untuk memodelkan struktur bawah permukaan menggunakan data microtremor guna melengkapi data mitigasi bencana gempa bumi. Data microtremor dianalisis menggunakan metode Horizontal to Vertical Spectral Ratio (HVSR) untuk menghasilkan kurva HVSR, yang kemudian diinversi untuk menentukan stratigrafi berdasarkan kecepatan gelombang geser (Vs30). Hasil penelitian menunjukkan nilai faktor amplifikasi (A0) berkisar antara 1–14,49 H/V, frekuensi natural (f0) antara 0,6–8,7 Hz, dan nilai Vs30 pada rentang 189–883,9 m/s. Parameter ini selanjutnya digunakan untuk membuat peta sebaran yang memberikan gambaran distribusi spasialnya. Berdasarkan distribusi parameter tersebut, Kecamatan Kampung Melayu dikategorikan sebagai zona risiko gempa bumi tingkat sedang. Informasi ini diharapkan dapat mendukung pengambilan keputusan yang lebih baik dalam perencanaan tata ruang, pembangunan infrastruktur, serta langkah mitigasi bencana di masa mendatang.
A Backpropagation Neural Network Algorithm in an Optical System for Detecting Borax and Formalin Contaminants in Food
Authors: Novianas Hafis , Wirman Shabri Putra , Fitrya Neneng
Published: February 2025

Bolin Detektor adalah alat pendeteksi boraks dan formalin yang mengidentifikasi kontaminasi berdasarkan perbedaan warna, namun masih memiliki kekurangan. Penelitian ini membangun jaringan saraf tiruan (JST) untuk meningkatkan performa Bolin Detektor. Arsitektur yang digunakan adalah backpropagation, dengan metode pelatihan traingdx, traincgb, traincgf, dan traincgp, serta variasi hidden layer dan neuron. Hasilnya, JST mampu mengenali 100% data pelatihan dan 97,83% data pengujian. Akurasi terbaik dicapai dengan metode traincgb, menggunakan 85 neuron pada hidden layer pertama dan 40 neuron pada hidden layer kedua..
Assessing the Chemistry and Negative Impacts of Alcoholic and Non-Alcoholic Beverage Consumption in Nigeria: A Public Health and Socioeconomic Perspective
Authors: Eberendu Kizito O. , Eze Victor C. , Nlemchukwu Blessing N. C. , Otuokere Ifeanyichukwu E.
Published: February 2025

This review explores the negative impacts of alcoholic and non-alcoholic beverage consumption in Nigeria, focusing on health, socioeconomic, and environmental dimensions. Alcoholic beverages, widely consumed in both urban and rural settings, are linked to significant health challenges such as liver diseases, cardiovascular issues, and mental health disorders, as well as social problems like domestic violence and road traffic accidents. Non-alcoholic drinks, particularly sugary soft drinks and energy drinks, contribute to rising rates of obesity, diabetes, and dental caries, exacerbating the nation's public health burden. Additionally, the unregulated production and distribution of some beverages pose risks of contamination and toxic exposure. Socioeconomic impacts include the strain on healthcare systems and reduced productivity due to alcohol-related absenteeism and illnesses. Furthermore, beverage production contributes to environmental degradation, including water pollution and excessive waste generation from packaging materials. This review highlights the urgent need for comprehensive public health strategies, stricter regulatory policies, and community-level interventions to mitigate the adverse effects of beverage consumption in Nigeria. Future research and policy recommendations should prioritize sustainable practices, consumer education, and improved healthcare responses to address this multifaceted issue.
A propósito de "¿me entendés?" en el español de la Argentina
Authors: H. Boretti Susana
Published: February 2025

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ANALISIS PENERAPAN PENGENDALIAN INTERNAL PERSEDIAAN DI PT TERNYAMAN
Authors: Ario Jayakrisna  , Paramitadewi Hyasshinta Dyah Sweztika Lukitaning
Published: February 2025

PT Ternyaman merupakan perusahaan yang menjual berbagai alat perlengkapan rumah tangga serta dekorasi untuk menghias rumah. Oleh karena itu, penilaian persediaan yang akurat penting dalam menjalankan kegiatan operasi bisnis dan menentukan kesehatan keuangan perusahaan. Karena jumlah persediaan yang sangat banyak dan tersebar di berbagai lokasi, tidak jarang terjadi selisih saat pergecekan fisik persediaan. Untuk itu, penelitian ini bertujuan untuk menganalisis penerapan pengendalian internal terkait persediaan yang telah diterapkan oleh perusahaan. Data yang digunakan adalah data primer yang langsung diperoleh dari perusahaan. Metode yang digunakan adalah metode penelitian lapangan dan kepustakaan.Pengumpulan data dilakukan dengan cara wawancara, observasi, dan analisis data stock opname (SO) selama enam bulan, dari Juli – Desember 2023. Beberapa kelemahan pengendalian internal yang dapat menjadi perhatian manajemen perusahaan antara lain tidak adanya SOP, peletakan CCTV yang kurang tepat, serta peningkatan selisih perhitungan fisik dari November–Desember yang memberikan peringatan akan kurangnya pengetatan dalam pengendalian internal.
EFISIENSI INVESTASI, TATA KELOLA, DAN NILAI PERUSAHAAN: STUDI PADA SEKTOR MANUFAKTUR
Authors: Tampenawas Jeremiah David Rianoto , Kusumadewi Ni Luh Gde Lydia
Published: February 2025

The research analyzes the effect of investment efficiency, independent board of commissioners, and audit committees on the firm value of manufacturing firms listed on the Indonesia Stock Exchange in 2020–2022. This research uses a purposive sampling method, choosing 23 manufacturing companies that published complete financial statements annually. We use Tobin's Q to measure firm value, ROA, and sales growth residuals to capture investment efficiency. In contrast, independent commissioners and audit committees are assessed based on the proportions and frequency of meetings. The results show that investment efficiency and independence commissioners positively affect firm value. The audit committee has a significant effect. These findings add to the corporate governance literature. They can facilitate investors during their decision-making by providing firm-level insights.
AN APPROACH TO FIND LINKAGE BETWEEN AGGRESSION PROFILES AND GENETIC VARIATIONS OF BDNF, HTR2A AND DRD4
Authors:   V.P. Serbsky National Medical Research Center for Psychiatry and Narcology, Moscow, Bairamova S.P.
Published: February 2025

In studies of genetic factors underlying aggressive behavior in humans, reproducing previously obtained results is often challenging due to the heterogeneous nature of aggression. As a result of this study, a method for the multidimensional analysis of psychometric and genetic data has been proposed. This method, based on machine learning techniques, enables the establishment of aggression profiles and the identification of associations with genetic polymorphisms.
DEVELOPMENT OF A MODEL FOR THE CLASSIFICATION OF PATHOLOGICAL CONDITIONS USING OPTICAL SENSORS
Authors:   Institute for Analytical Instrumentation RAS, Saint Petersburg, Glebov S.N. ,   S.M. Kirov Military Medical Academy, Saint Petersburg, Liamina J.V. , Mazing M.S. , Polyakov A.S. , Noskov Y.A. , Zaitseva A.Y.
Published: February 2025

Optical sensors represent a promising direction for the development of non-invasive diagnostic methods for pathological conditions. The information received from the sensors is presented as a multidimensional array of data. Its feature is the content of a large
amount of hidden information, as well as implicit relationships in the data, which can be identified using machine learning methods.
SOFTWARE FOR IDENTIFYING OF POTENTIAL TARGETS OF CRISPR-CAS GENE EDITING IN ANTIBIOTIC-RESISTANT BACTERIA
Authors:   University of Tyumen, Goglev A.V. , Pastuhova N.D. ,   Institute of Experimental Medicine, Saint Petersburg
Published: February 2025

The CRISPR-Cas gene editing method can be one of the possible ways to overcome bacterial antibiotic resistance. In this
study, we developed a software to identify the best gene editing targets based on RNA sequencing data from the Klebsiella pneumoniae
MGH66 strain.
IDENTIFICATION OF DROSOPHILA MELANOGASTER GENES THAT ARE DIFFERENTIALLY EXPRESSED WITH LOW CONFIDENCE BUT CONTRIBUTE MEANINGFULLY TO THE HEAT SHOCK RESPONSE
Authors:   Institute of Cytology and Genetics SB RAS, Novosibirsk, Deryuzhenko M.A. , Gruntenko M.G.
Published: February 2025

Information loss is one of the key problems of modern transcriptome data analysis. One of the reasons for its occurrence is data
cutoff by confidence threshold. Partially, this problem can be solved by increasing the sample size. However, it is a partial solution. In
this paper, a new approach to the study of genes at different confidence levels is demonstrated using a meta-analysis of the response
to heat shock in Drosophila melanogaster as an example.
EVALUATION OF THE SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS AND THE COMPOSITION OF SECONDARY METABOLISM GENE CLUSTERS IN A THERMOPHILIC STRAIN STREPTOMYCES
Authors:   Irkutsk State University, Dmitrieva M.E. , Dmitrieva V.N. , Potapova N.A. , Axenov-Gribanov D.V.
Published: February 2025

As part of the experiment, a screening of secondary metabolites and an assessment of the gene clusters composition of the thermophilic strain Streptomyces were conducted. The synthesis of compounds belonging to the nocardamine family was recorded. Five
secondary metabolism gene clusters responsible for the synthesis of compounds such as geosmin, ectoine, nocardamine, kuramycine,
and flaviolin were identified.
ANALYSIS OF THE GENETIC STRUCTURE OF THE HONEY BEE APIS MELLIFERA ON THE TERRITORY OF THE REPUBLIC OF BELARUS
Authors:   Institute of Genetics and Cytology NAS of Belarus, Minsk, Dobysh O.I. , Tsar A.I.
Published: February 2025

To accurately identify honey bees belonging to different evolutionary branches, a reference sample was created based on the
analysis of microsatellite markers and statistical data processing.
STUDY OF THE STRUCTURE OF THE PORPHYRIN RING WITHIN THE CYTOCHROME С-CARDIOLIPIN-ACTIVATED COUMARIN С525 CHEMILUMINESCENCE UNDER THE ACTION OF THE COMPLEX
Authors:   Pirogov Russian National Research Medical University, Moscow, Levchenko I.N. ,   Moscow Aviation Institute (National Research University),   Sechenov First Moscow State Medical University,   Perm National Research Polytechnic University,   Lomonosov Moscow State University, Pankratov V.S. , Vladimirov G.K. , Levchenko A.A. , Volodyaev I.V.
Published: February 2025

Our results could become the basis for the creation of new drugs. Which are elements of the cell and have a therapeutic effect.
Modulation and mathematical modeling of the porphyrin ring in as part of a heterogeneous catalyst of cytochrome C complex with cardiolipin, surrounded by a fluorescent probe of a physical activator of the natural dye coumarin С525 showed that the chemiluminescence
of luminol is 3–4 orders of magnitude higher than that of the excited ketones, with cardiolipin itself being a “double” glycerophospholipid that is is considered a proton trap and has immune properties.
ACUTE BLOOD LOSS INDUCES INCREASED EXPRESSION OF THE PAMP GENE CLEC5A IN MURINE BONE MARROW ERYTHROID CELLS
Authors:   Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Nazarov K.V. , Shevchenko Y.A. , Perik-Zavodskii R.Y. , Perik-Zavodskaia O.Y. , Alrhmoun S. , Volynets M.O. , Sennikov S.V.
Published: February 2025

Hemorrhage, a condition that accompanies most physical trauma cases, affects all bone marrow lineages, including erythroid
nucleated cells. In this study, we studied the immune response genes transcriptome of murine erythroid cells to acute blood loss using
NanoString immune transcriptome profiling. We observed that acute blood loss up-regulate pathogen-associated molecular pattern
sensing gene Clec5a in post-acute blood loss murine bone marrow erythroid cells. We believe that the up-regulation of the Clec5a gene
in bone marrow erythroid cells could help bone marrow erythroid cells detect and eliminate pathogens with the help of reactive oxygen
species and antimicrobial proteins calprotectin and cathelicidin, the genes of which (S100a8, S100a9, and Camp) dominate the expression in bone marrow erythroid cells of mice.
TRANSCRIPTOMIC ANALYSIS OF CELL LINES WITH NORMAL AND DEFECTIVE MITOPHAGY
Authors:   Institute of General Pathology and Pathophysiology, Moscow, Pleshko E.M. , Borodko D.D. , Orekhov N.A. , Omelchenko A.V.
Published: February 2025

The search for genes involved in the regulation of mitophagy is a promising direction in anti-inflammatory therapy. We performed a transcriptomic analysis of cell lines with normal and defective mitophagy and identified 7 differentially expressed genes. They
control a number of important processes, including cellular communication, and can be regulators of mitophagy.
COMPARATIVE ANALYSIS OF BIOINFORMATIC ALGORITHMS FOR SEARCHING FOR PROFAGES IN THE BACTERIAL GENOME
Authors:   Ural Federal University named after the First President of Russia B.N. Yeltsin, Yekaterinburg, Rezaykin A.V. ,   Ural State Medical University, Yekaterinburg,   Moscow Institute of Physics and Technology,   NPO Biosintez Ltd, Moscow, Mikushin P.V. , Nizovtseva I.G. , Chigireva A.A. , Dubova V.I. , Glebova A.E.
Published: February 2025

This study presents a comparative analysis of four prophage prediction tools: PHASTEST, Phigaro, VIBRANT, and PhiSpy.
The complete genomes of three Methylococcus capsulatus strains were analyzed using these tools, which employ distinct algorithms
based on homology searches, machine learning, or a combination of both approaches. The results revealed significant discrepancies in prophage boundary prediction, gene content, and functional assessment. This analysis highlights that utilizing multiple tools
with complementary algorithms enhances the accuracy of prophage identification and minimizes both false-positive and false-negative
predictions.
IDENTIFICATION OF INTROGRESSIVE HYBRIDIZATION SEGMENTS IN THE WHEAT GENOME USING GBS
Authors:   All-Russia Research Institute of Agricultural Biotechnology, Moscow, Syedina N.M. ,   All-Russia Research Institute of Radiology and Agroecology, National Research Centre “Kurchatov Institute”,   National Research Centre “Kurchatov Institute”, Moscow, Ermolaev A.S. , Ulyanov D.S. , Voronezhskaya V.S. , Vasiliev A.V. , Toshchakov S.V. , Divashuk M.G.
Published: February 2025

This study presents an approach for quantitative assessment of the content of parental genomic material in the offspring genome based on GBS sequencing data. In addition, the method allows for assessing the distribution of parental material in the offspring
genome and identifying recombination points and chromosomal rearrangements. Quantitative assessment allows drawing a conclusion
about the contribution of each parent to the offspring genome, which is important for the breeding process in backcrossing and introgression selection to minimize the amount of genetic material of one parent in the offspring.
Transtornos psiquiátricos na gestação
Authors: Andrade Yasmin Nunes , Bellemo Ana Isabel Sobral
Published: February 2025

Objetivo: reunir informações e conhecimento sobre Transtornos Psiquiátricos na gestação no intuito de difundir o tema ajudando os profissionais de saúde a adequar estratégias de cuidado para minimizar ou evitar tais transtornos, proporcionando que a gestante tenha um período gravídico saudável. Métodos: Trata-se de uma revisão integrativa feita na Biblioteca Virtual de Saúde (BVS), com o descritor Transtornos Psiquiátricos na gestação dentro dos últimos 5 anos, seguido de filtros e critérios de exclusão determinados. Resultados: Foram selecionados 11 artigos. A gestação traz alterações em relação a necessidade de adaptação para a nova vida gerada além da reestruturação na vida da mulher, contribuindo para o aumento da instabilidade emocional, ansiedade e sintomas depressivos. Fatores como estrutura familiar disfuncional, abuso de substâncias e rede de apoio frágil ou nula podem agravar esse sofrimento. É fundamental a identificação e intervenção precoce e promotoras de bem-estar materno, considerando o que repercute negativamente para a mãe e feto. O encaminhamento e acompanhamento no pré-natal pode minimizar tais agravos durante a gestação. Considerações Finais:  Ações básicas de humanização, acolhimento e escuta qualificada na Assistência Pré-Natal, são primordiais no atendimento da equipe a essas gestantes. A melhora nesse olhar profissional pode minimizar danos para mãe e filho.
A efetividade da imunoterapia em diferentes tipos de câncer: um estudo ciênciometrico
Authors: Frota Ana Karolinne Ferreira , Jobim Kelly-Ann Rayol Frederico , Silva Fábio Casagrande Jobim da , Martins Lígia Sabrina Monteiro , Lima Laila Sofia , Martins João Luís Ribeiro , Freitas Karla Vieira da Costa , Almeida Nathalie Xavier de
Published: February 2025

Objetivo: Avaliar a efetividade da imunoterapia em uma ampla gama de neoplasias. Métodos: Estudo cienciométrico utilizando as bases de dados PubMed, Scientific Electronic Library Online (Scielo) e Science Direct. Seguiu critérios de inclusão que abrangem artigos publicados nacional e internacionalmente, sem restrição de período de publicação e em estudos clínicos e pesquisas de análise disponíveis gratuitamente. Para o tratamento dos dados foram empregados programas como VosViewer, Mendeley e Excel. Resultados: Foram incluídos 32 artigos. A publicação dos artigos varia de 1969 a 2024, oferecendo uma visão abrangente da evolução da pesquisa em imunoterapia ao longo de mais de meio século. Isso permite aos pesquisadores traçar o progresso e identificar áreas de crescimento e interesse contínuo. Observou-se um aumento notável na quantidade de pesquisas publicadas nos anos mais recentes, refletindo um interesse cada vez maior e um maior investimento na área de imunoterapia contra o câncer. Conclusão: Estudos sobre a temática está em uma trajetória promissora, com avanços significativos e um futuro repleto de potencial. A medicina de precisão, a tecnologia de ponta e a colaboração internacional estão impulsionando essa área, tornando-a uma parte essencial da oncologia moderna.
Association between high-risk human papillomavirus and cervico-vaginal infections in tribal women screened for cervical precancers and cancers in Maharashtra, India: A cross-sectional study
Authors: Munne Kiran , Birje Shantanu , Patil Anushree , Akula Anamika , Mayekar Anjali , Bhekare Ganga , Kumari Sayantika , Babu Sonu , Tendulkar Leena , Kerkar Shilpa , Patil Prerana , Tandon Deepti , Pathuthara Saleem , Deodhar Kedar , Biswas Sanjay , Begum Shahina , Pramanik Jayanti Mania , Pimple Sharmila , Joshi Beena , Salvi Neha , Chauhan Sanjay
Published: February 2025

Background

The vaginal microenvironment is thought to impact infection and persistence of the human papillomavirus which is a necessity for cervical carcinogenesis. Tribal women are at risk for human papillomavirus and cervicovaginal infections due to polygamy, poor hygiene, and illiteracy.

Aims

We evaluated the association of common cervico-vaginal infections with human papillomavirus infection and cervical precancers among the tribal women of Dahanu taluka, Maharashtra, India.

Methods

For this cross-sectional study, tribal women from Dahanu taluka were recruited. Cervical brushing samples were collected from them and tested for human papillomavirus by the Hybrid Capture 2 method and polymerase chain reaction for Chlamydia trachomatis. Vaginal samples were collected for gram staining and examined for candidiasis and bacterial vaginosis, followed by visual inspection of the cervix with acetic acid.

Results

A total of 501 sexually active tribal women were recruited, among whom the human papillomavirus infection rate was 6.5%. Evaluation of vaginal smears by Nugent’s scoring revealed bacterial vaginosis in 208 (41.5%), candidiasis in 30 (5.98%), and chlamydia in five (1%) participants. Bacterial vaginosis prevalence was higher in high-risk human papillomavirus-positive women. The presence of clue cells was associated with human papillomavirus positivity, suggesting an association between bacterial vaginosis and human papillomavirus infection and indicating an increased risk of human papillomavirus infection on co-infection with bacterial vaginosis.

Limitations

Only tribal women were screened, with no screening for other sexually transmitted infections. Since participants were recruited from healthcare centres instead of random sampling, this may have affected infection rate estimates. Due to regional differences in sexual behaviours and gynaecological morbidities, our findings cannot be generalised to tribal women from other regions.

Conclusion

Early detection and management of reproductive tract and sexually transmitted infections is paramount for preventing co-infections and reduces the risk of cervical carcinogenesis.
Unveiling the Role of Pain Catastrophising as a Predictor of Fear of Personal Death amongst Brain Tumour Patients
Authors: Mathreja Diksha , Mansuri Arefa
Published: February 2025

Objectives:

According to the National Health Portal, brain cancer is witnessing an upward curve in India. The reports by medical professionals suggest that brain tumours will become the second most common cancer by 2030. Any life-threatening illness not only impacts the physical well-being of the patient but also affects the mental well-being of the patient. As an interdisciplinary field, psychology aims to understand the psychosocial components of an illness that goes beyond the realm of medical treatments. Hence, the present study focused on two psychological constructs, namely Pain Catastrophising and Fear of Personal Death. The present research aims to evaluate the relationship between Pain Catastrophising and Fear of Personal Death as well as assess the predictive role of Pain Catastrophising for Fear of Personal Death.

Materials and Methods:

A correlational design was adopted for the present study. The sample consisted of 180 patients who were diagnosed with a brain tumour and were scheduled for surgery for the removal of the tumour. A purposive sampling technique was used for the selection of the sample. Data were collected on two psychological measures, namely the Pain Catastrophising Scale and the Fear of Personal Death Scale. Pearson’s product-moment method and regression analysis were employed for statistical analysis.

Results:

The findings highlight that there exists a positive association between the two components of Pain Catastrophising, namely Magnification (r = 0.644, P < 0.01) and Helplessness (r = 0.456, P < 0.01) with the Fear of Personal death. Rumination (0.026, P > 0.05) component exhibited no association with Fear of Personal Death. Linear regression analysis reveals that magnification (R = 0.644, R2 = 0.414, F = 125.861, P < 0.01) and helplessness (R = 0.456, R2 = 0.208, F = 46.857, P < 0.01) are significant predictors of Fear of Personal Death for the selected sample.

Conclusion:

Pain Catastrophising tendencies and feelings of Fear of Personal Death are prevalent amongst the selected cohort. Pain-catastrophising components are significantly associated with fear of personal death (FPD) and are also significant predictors of FPD amongst brain tumour patients.
Lived Experiences of Pancreatic Cancer Patients Undergone Whipple Procedure: A Qualitative Study
Authors: Chauhan Priyanka , Kaur Sukhpal , Singh Neena Vir , Kaur Maninderdeep , Gupta Rajesh
Published: February 2025

Objectives:

Pancreatic cancer is a devastating illness with significant impacts on patients’ health-related quality of life (HRQoL). The Whipple procedure, a common surgical intervention for pancreatic cancer, presents numerous challenges for recovery and adaptation. This study aims to provide a comprehensive understanding of the lived experiences of patients’ post-Whipple surgery. The objective of the study is to explore the lived experiences of patients having cancer of the pancreas undergone Whipple’s procedures.

Materials and Methods:

A qualitative phenomenological approach was employed to delve into the experiences of patients who underwent the Whipple procedure. Twenty-seven patients attending the surgical gastroenterology outpatient department of a tertiary care institution for follow-up were enrolled in the study. The patients were enrolled consecutively till the saturation of data. An interview guide was used to collect the data. The data were analysed using Colaizzi’s method to identify the key themes.

Results:

The participants, with a mean age of 51.61 ± 10.89 years, were predominantly male (61.7%) and Hindu (70%) by religion. Most participants had tumours of the head of the pancreas and were hospitalised for 16–30 days at the time of surgery. Thematic analysis revealed eleven themes, i.e. post-diagnosis reaction, burden of the disease, physical problems, socioeconomic burden, psychological issues, impact on social life, financial support, disturbed body image, spirituality, communication with healthcare professionals and hospital experiences.

Conclusion:

This study underscores the multifaceted challenges faced by pancreatic cancer patients post-Whipple procedure, highlighting the importance of addressing physical, emotional and socioeconomic aspects to improve their HRQoL. The findings can inform healthcare professionals in developing holistic care strategies tailored to these patients’ unique needs.
Inter-modality correlation across invasive and noninvasive angiography in the three-dimensional assessment of cerebral aneurysms
Authors: Johnson Mark D. , Street Seth , Prestigiacomo Charles J.
Published: February 2025

Background:

Non-invasive and invasive methods of cerebral angiography, including computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA), are commonly used to characterize and follow cerebral aneurysms. Prior work has validated two-dimensional size measurements across these modalities. Our study aims to compare the reliability of three-dimensional (3D) shape measurements across CTA, MRA, and DSA.

Methods:

A subset of cerebral aneurysms in which more than one form of angiography was performed was selected. Aneurysms were included if they did not change in size or shape between angiographic studies. Aneurysm domes were segmented, and morphometric features were measured consistent with prior reports. Intraclass correlation coefficients (ICCs) for each morphometric measure were calculated using a two-way mixed effect model.

Results:

A total of 65 individual aneurysms from 55 patients were included in the study. The majority of aneurysms were imaged with DSA and CTA (43%) or MRA and CTA (40%), with 14% having DSA, MRA, and CTA available for review. The majority of aneurysms were located in the anterior circulation (77%), with an average size was 5 (4–8) mm. ICC ranged from 0.66 to 0.99 for 3D morphometric features, corresponding to “moderate” to “excellent” correlation. Sphericity and non-sphericity index showed the lowest ICC values. With the exception of these two variables, 3D morphometrics showed “good” or “excellent” reliability. No significant difference in mean absolute difference was noted across imaging modalities for each morphometric feature.

Conclusion:

The majority of 3D morphometric measures show “good” to “excellent” reliability across CTA, MRA, and DSA, allowing for comparison across imaging modalities.
Cost outcomes of pituitary adenoma resection: The use of a hybrid microscopic/endoscopic surgery
Authors: Cole Kyril L. , Rennert Robert C. , Rawanduzy Cameron A. , Brandel Michael G. , Findlay Matthew C. , Azab Mohammed A. , Karsy Michael , Couldwell William T.
Published: February 2025

Background:

The pathogenesis, surgical techniques, and outcomes of pituitary adenomas (PAs) remain variable. We compared our surgical techniques and perioperative/long-term PA outcomes to highlight the hybrid microscopic/endoscopic technique used to optimize efficiency, cost savings, and outcomes in PA surgery.

Methods:

Consecutive PA cases performed from January 2017 through February 2020 were evaluated retrospectively. A cost analysis by surgical approach was performed combining this primarily microscopic series, with endoscopic visual assist, and a separate cohort of consecutive intra-institutional endoscopic-only PA resections.

Results:

Among 160 patients included in the main cohort analysis (mean age 51.5 ± 16.2; 89 females [55.6%]), a microscope was used in 81.9% of cases, with endoscopic assistance (hybrid) or the endoscope alone used in the remaining cases. Surgical complications occurred in 5 cases (3.1%): postoperative diabetes insipidus in 3 (1.9%), electrolyte imbalances requiring additional drug treatment in 3 (1.9%), and syndrome of inappropriate anti-diuretic hormone release in 2 (1.2%). Thirty-three additional patients were included in the cost analysis (193 total). Patients treated with a microscopic-only approach had the lowest operating time (mean normalized operating room costs 1.00 [95% confidence interval (CI) 0.95, 1.04], P < 0.001; mean normalized total direct costs 5.00 [95%CI 4.69, 5.31], P = 0.008), with hybrid and endoscopic-only approaches having higher comparable operating times and costs.

Conclusion:

PA surgery using a primarily microscopic approach (with endoscopic assistance for complex cases) remains a safe, efficient, and cost-effective strategy and results in shorter anesthesia time to reduce patient complications while maintaining excellent endocrinologic outcomes.

Keywords:

Endoscope, Hybrid approach, Microscope, Pituitary adenoma, Transnasal surgery, Transsphenoidal surgery
Dry needling for mechanical neck pain: A systematic review and meta-analysis of randomized controlled trials
Authors: Aleid Abdulsalam M. , Aljabr Abdulmajeed Abdulaziz , Aldanyowi Saud Nayef , AlAidarous Hasan Ali , Aleid Zainab Mohammed , Alharthi Abdulaziz S. , Alsubaie Mutlaq Naheitan , AlOraini Lama Ibrahim , Almoslem Abdulrahman Rashed , Al Mutair Abbas
Published: February 2025

Background:

Dry needling (DN) has emerged as a potential treatment for mechanical neck pain, but the evidence remains inconclusive. This study aimed to assess the efficacy of DN in improving pain and functionality in patients with chronic mechanical neck pain.

Methods:

A systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted following the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Databases, including PubMed, Cochrane Library, Scopus, and Google Scholar, were searched from December 2013 to January 2024. Studies involving adult participants with chronic mechanical neck pain treated with DN were included in the study. The primary outcomes were pain pressure threshold (PPT), Neck Disability Index (NDI), and cervical range of motion. Statistical analysis used a random-effect model.

Results:

Nine RCTs with a total of 540 participants were included in the study. DN significantly improved the PPT with an MD of 0.52 (95% confidence interval [CI], 0.39–0.65; P < 0.001). NDI also showed a significant improvement, with an MD of −0.68 (95% CI, −1.32–−0.05; P = 0.04). In terms of cervical range of motion, DN improved flexion (MD 4.07, 95% CI, 0.39–7.75; P = 0.03) and right rotation (MD 8.20, 95% CI, 3.05–13.35; P = 0.002), but no significant differences were observed in extension, left rotation, or lateral flexions (P > 0.05).

Conclusion:

DN appears effective in short-term pain relief and functional outcomes for patients with mechanical neck pain but shows limited impact on the cervical range of motion.
Измерение и реконструкция диаграммы направленности антенны при направленном облучении с близкого расстояния
Authors: Абухадма Л.К. , Чони Ю.И.
Published: February 2025

Обсуждается на первый взгляд неожиданный эффект, который проявляется в том, что с увеличением апертуры вспомогательной антенны, облучающей испытуемую антенну с относительно узкой диаграммой направленности (ДН), угловая зависимость принимаемого сигнала (кажущаяся ДН) сужается вместо того, чтобы расширяться из-за снижения интенсивности облучающего поля на краях антенны. Результаты моделирования показывают, что это вызвано тем, что фазовый фронт облучающего поля спрямляется , и таким образом, уменьшение фазовых искажений оказывается фактором более существенным, чем снижение амплитуды поля на краях испытуемой антенны. При этом результат реконструкции ДН практически не зависит от амплитудной неравномерности облучающего поля, что вполне объяснимо использованием его предварительным зондированием.

Introduction. Currently, measuring devices called vector analyzers of circuits and signals have become available and allow to carry out automatic measurements of amplitudes and phases. It forces the interest in the practical application of methods that allow retrieving the true radiation pattern by irradiating the tested antenna at a close distance. This is topical for measurements performed in compact anechoic chambers. The use of directed radiation in this case, on the one hand, reduces reflections from the chamber walls, and on the other hand, increases the inhomogeneity of the irradiating field. The aim of the research was to elucidate the influence of the directional property of the auxiliary antenna, that produces the irradiating field, on the measurement process and the accuracy of the radiation pattern retrieval, under the framework of the methodology of a converging cluster of plane waves. To achieve the goal, simulating of measurement and data processing processes was carried out when the size of the auxiliary antenna varied. The simulation findings proved that the retrieval accuracy does not depend on the nature of the irradiating field. This can be explained by the fact that at first the sounding of the irradiating field is performed and the converging cluster of plane waves corresponding to the characteristics of the irradiating field is synthesized. As for the initial measurements of the antenna radiation pattern, calculations showed that even with the moderate lengthening the auxiliary antenna, the measured radiation pattern approaches the true radiation pattern, despite the fact that the inhomogeneity of the amplitude relief of the irradiating field increases. It was found that this tendency is caused by the effect of straightening the phase front of the irradiating field. Conclusions. The simulation findings proved the efficiency of the retrieval of the radiation pattern within the framework of the methodology of a converging cluster of plane waves, in a practically significant case when measurements are performed in compact chambers with the use of a directional auxiliary antenna.
ОЦЕНКА ЁМКОСТИ ПЛОСКОГО КОНДЕНСАТОРА С УЧЁТОМ ШЕРОХОВАТОСТИ ПОВЕРХНОСТИ ЭЛЕКТРОДОВ
Authors: Евдокимов Ю.К. , Фадеева Л.Ю. , Сагдиев Р.К. , Валеев Б.М.
Published: February 2025

Рассмотрено влияние шероховатости электродов на величину ёмкости плоского конденсатора. Роль шероховатости существенно возрастает с уменьшением межэлектродного расстояния, соизмеримого с масштабом неоднородностей поверхности. Предложено соотношение для количественной оценки ёмкости с учётом шероховатости. Приведены результаты экспериментальных измерений ёмкости конденсатора с шероховатыми пластинами при различных уровнях чистоты обработки поверхности.

Introduction. The rapid development of micro- and nano-technologies poses the topical problems of roughness of various surfaces, heterogeneities of surface edges and their influence on the electrophysical and electrical characteristics of radio electronics elements and various sensors. State-of-the-art technologies and processing methods allow to obtain fairly accurate and smooth bounds and surfaces of elements. However, for submicron and nanoscale devices, the scale of the length, width, height of the elements and the distances between the elements become comparable with the scale of heterogeneities and the level of processing. Additionally, this results in the occurence of new electrical, electrophysical, and physicochemical properties of such structures obtained both artificially and naturally (for example, crystalline and various ordered systems, etc.). Furthermore, there is posed a problem of quantitative description of the dependence of electrical and other properties on the heterogeneity and roughness of the elements and materials. The aim of the research was to theoretically estimate capacitance of a flat capacitor with rough surface electrodes and its experimental validation. Method and findings. In the experiment, we proposed a method for evaluating the validity of the equation describing a fractal model of a capacitor. The principle of the method is to measure the electric capacitance by a high-precision device for electrodes identical in geometry but with different roughness and at different interelectrode distances. Conclusions. Research finding showed that the proposed improved equation for calculating the capacitance, considering the fractal dimension of the roughness and heterogeneity of the electrode surface, significantly corrects the classically calculated capacitance. The surface roughness results in an increase in the surface area S of the capacitor plates. The derived equation also allows to predict the electrical properties of such electrode systems, linking them with the quality and technology of the surface treatment.
МЕТОДИКА АУДИТА ИНФОРМАЦИОННОЙ БЕЗОПАСНОСТИ ПРЕДПРИЯТИЯ С ИСПОЛЬЗОВАНИЕМ ПРИЧИННО-СЛЕДСТВЕННОЙ ДИАГРАММЫ
Authors: Чекулаева Е.Н. , Кубашева Е.С.
Published: February 2025

Представлена методика проведения внутренней аудиторской проверки, основанная на анализе причинно-следственных связей в системе информационной безопасности предприятия. Рассмотрена структура проведения аудита информационной безопасности предприятия и предложены основные направления деятельности в области аудита безопасности информации.

Introduction. A significant part of the audit provides a detailed pattern of data security and company security, that allows to identify the problem and ensure the correct reliable audit structure. On time audit of information security (IS) allows to quickly and reliably estimate the current state of the company data and take the right decision to ensure information security. One of the reasons for these criteria lies in the lack of real tools and tasks to plan, evaluate and control the management of the results of the company. The aim of the research is to increase the efficiency of estimating the characteristics of a company information security audit by using the cause-and-effect diagrams of threats and vulnerabilities to information security. Paper presents a methodology for analyzing the characteristics of a company information security audit by using a cause-and-effect diagram. A piece of the life cycle of an IS audit gives an estimate of the company security in order to determine which resources and from which threats should be protected, and also how different resources should be protected. The structure of the IS audit provides a qualitative and quantitative verification of the entire audit process in the company. The approach to carrying out an internal audit and self-assessment of information security is based on the method of analysis of cause-and-effect diagram of threats and vulnerabilities in the company information security system. It will optimize the process of obtaining qualitative and quantitative estimates of the current state of the company information security, reveal current threats, and block if necessary leakage of confidential information. Conclusion. The developed methodology for carrying out an internal audit developed by the authors, based on the method of estimating cause-and-effect diagram allows to identify the most vulnerable parts in the company information security system. Being universal, the method can be employed at the any company, allowing one to draw up own unique schemes (cause-and-effect diagrams) adapted to the specific conditions of the company. Based on the diagrams one can produce reports of internal audits and make changes to the information and data security system.
СИСТЕМА КОНТРОЛЯ СКОРОСТИ СНАРЯДА НА ВЫХОДЕ СТВОЛА С ИСПОЛЬЗОВАНИЕМ МНОГОАДРЕСНЫХВОЛОКОННЫХ БРЭГГОВСКИХ РЕШЁТОК
Authors: Сахабутдинов А.Ж. , Мисбахов Р.Ш. , Куликов Е.В. , Морозов Г.А. , Колесников В.Ю. , Липатников К.А. , Сарварова Л.М.
Published: February 2025

Представлена волоконно-оптическая система на основе трёх пар многоадресных волоконных брэгговских структур (МАВБС) отражательного типа (3l-ВБР), записанных в одном оптическом волокне. Система предназначена для контроля скорости снаряда на выходе ствола (ССВС) в реальном времени. Основной функцией системы является контроль ССВС через измерение в процессе выстрела времени прохождения волной кольцевой деформации ствола каждой из пар датчиков, закреплённых на поверхности ствола с различным базовым расстоянием. Волокно при этом установлено так, что каждая пара датчиков расположена вдоль своей направляющей ствола, угол между которыми с его осью составляет 120°, и подключена через циркулятор к зондирующему лазеру и интеррогатору. В отличие от других данная волоконно-оптическая система является радиофотонной, не требует использования сложных и дорогих вибрационно-неустойчивых оптико-электронных интеррогаторов для опроса датчиков и позволяет дополнительно контролировать параметры волны деформации ствола в шести точках на его выходе. Измеренная ССВС может быть использована для повышения точности прицеливания, индикации характеристик живучести ствола и установки сроков его эксплуатации по фактическому состоянию износа.

Introduction. Currently, a wide range of systems and devices has been developed for monitoring the projectile velocity at the barrel exit (PVBE) under the full-scale and laboratory conditions. The most common systems of monitoring PVBE are built on the basis of various types of sensors, mounted near the barrel exit at a certain base distance between them, and a unit for measuring projectile velocity. During the shot, a wave of ring strain, caused by the movement of the projectile, propagates along the barrel and induces a pulse-type response in the sensors at different time moments, depending on the PVBE. The PVBE measuring unit determines the velocity of the projectile in the barrel as a value directly proportional to the base distance and inversely proportional to the time difference between the responses of the two sensors.
ИСКАЖЕНИЯ ШИРОКОПОЛОСНЫХ ЛЧМ-ИМПУЛЬСОВ В СЛУЧАЕ НОРМАЛЬНОЙ И АНОМАЛЬНОЙ ДИСПЕРСИИ КВ-КАНАЛА
Authors: Рябова М.И.
Published: February 2025

Представлена методика синтеза ионограмм наклонного зондирования с применением многослойной квазипараболической сегментации. Проведены вычислительные эксперименты по исследованию дисперсионных характеристик преобладающих мод для радиолиний протяжённостью от 1 000 до 7 000 км. Установлены характеристики нормальной и аномальной дисперсии. Проведены оценки скорости чирпирования импульсной характеристики в широкополосных ионосферных КВ-каналах в зависимости от протяжённости трассы, времени суток и относительной частоты канала. Получены данные о дисперсионных искажениях огибающей импульсной характеристики канала с полосой пропускания 1 МГц и различной средней частотой, отражающие влияние чирпирования.

Introduction. It is acknowledged that in radar and wireless communication systems signals, typically, are wave packets consisting of harmonic oscillations and are finite in both the time and frequency domains. Due to the dispersion of the medium, the phase relations of the components of such packets are broken and they are distorted. In cases when a packet can be characterized by an envelope and a carrier, the concepts of phase velocity and group velocity are introduced. In dispersive media, the phase and group velocities are not equal, and therefore, in the coordinate system associated with the envelope, the carrier will move relative to it. Media with normal and anomalous dispersion are different. For inhomogeneous media, the problem of the type of dispersion is still poorly studied.
DOI: https://doi.org/10.25686/2306-2819.2021.2.38 ПРОГНОЗИРОВАНИЕ ЭКСПЛУАТАЦИОННЫХ ПОКАЗАТЕЛЕЙ ТЕЛЕКОММУНИКАЦИОННЫХ СИСТЕМ
Authors: Шерстнева А.А.
Published: February 2025

Разработаны математические модели функционирования телекоммуникационного объекта. Параметрами моделей являются эксплуатационные показатели и показатели надёжности системы контроля и диагностики. Приведены аналитические выражения для их вычисления. На основе методов теории фильтрации и модели авторегрессионного процесса предложен вариант решения задач прогнозирования статистических данных и вероятностей отдельных событий.

Introduction. Estimation of the quality of performance of telecommunication systems depends on the reliability of partial technical devices and their components. Reliability estimation is based on the calculation of operational and design reliability indicators. The performance values are calculated according to the statistical data of the monitoring and control system. To derive analytical expressions for determining the calculated indicators, there were developed mathematical models which reflect the technological process of functioning. The mathematical models are presented in the form of a diagram of states that a technical object keeps during operation. The diagram also includes states under the condition of imperfect reliability of the monitoring and diagnosing system. Its imperfect is caused by the presence of control errors of the first, the second and the third kind. The aim of the study is to identify mathematical models by solving empirical equations and forecasting the performance indicators of the reliability of a telecommunication system, as well as a monitoring and diagnosing system. There were used two types of mathematical models. The first model is based on theoretical assumptions. The second one includes only the states observed during system operation. Findings.There were derived analytical expressions for calculating reliability indicators. By comparing and analyzing the outcomes, there were derived equation systems that allows to calculate the availability ratio, the average limitation time for traffic transmission and the probability of control errors. On the basis of the set-theoretic analysis of the outcomes, there is proposed a solution for the problems of forecasting statistical data and the probabilities of particular events. The solution is based on the use of filtration theory methods and an autoregressive process model. Estimated values of parameters of autoregressive models were obtained by three different methods.