bluuebunny/crossref_metadata_2025 huggingface dataset:
Ethical Issues in Advertising Weight Loss Drugs to Patients: A Synthetic Experiment Using LLMs (Large Language Models) to Suggest How Education Might Help People to Address the Issues
Authors:   Cognitive Behavioral Insights, LLC, Albany, NY, USA, Moskowitz Howard R
Published: May 2024

Using LLMs (large language models), the paper shows how to approach the ethical issues involved in the increasingly popular strategy of advertising prescriptiononly weight loss drugs directly to consumers. The paper shows the background, the issues, the benefits of creating “stories” to give the topic a deeper sense of reality. The paper finishes by using LLMs to synthesize and then prescribe ten different aspects of a course devoted to critical thinking about the topic.
Nanomembrane-Based Apheresis: A Simple and Safe Procedure for Preventing Cardiovascular Complications in Metabolic Syndrome
Authors:   Institute for Physical Medicine, Rehabilitation and Rheumatology “Dr Simo Milosevic” Igalo, Montenegro, Vjeroslava Slavic ,   Centre of Excellence for Biomedical Research
Published: May 2024

Introduction: Metabolic syndrome (MetS) encompasses various abnormalities, including obesity, arterial hypertension, and diabetes, posing significant cardiovascular risks. Novel interventions are needed to address these risks promptly. This study evaluates the efficacy and safety of Nanomembrane-based low-volume plasma exchange (LVPE) in reducing cardiovascular risk factors in MetS patients. Material and Methods: Forty-eight MetS patients (31.3% female, 68.7% male, mean age 50 years) underwent four cycles of LVPE using the Hemofenix device and nanotech membrane PFM 500. LVPE, performed every other day, removed 30% of circulating plasma, replaced with saline. Blood samples were collected pre- and post-treatment for biomarker assessment. Results: LVPE significantly reduced systolic and diastolic blood pressure (p<0.001), sedimentation rate (p<0.0001), glucose (p<0.001), cholesterol (p<0.001), triglycerides (p<0.011), high-density lipoprotein cholesterol (p<0.006), fibrinogen (p<0.001), C-reactive protein (CRP) (p<0.02), and high-sensitivity CRP (p<0.06). No significant changes occurred in the complete blood count. Conclusions: LVPE emerges as a promising, minimally invasive intervention for reducing cardiovascular risk factors in MetS patients. By targeting proinflammatory and proatherogenic factors, LVPE could revolutionize MetS management and prevent cardiovascular complications. Future studies should optimize LVPE protocols and assess long-term efficacy in larger cohorts.
Development of Tourism Industry and Prospects of Employment Generation in Bihar
Authors: Dr Kalpana Kumari
Published: May 2024

Bihar is a land of rich diverse culture, a variety of traditions, historical and cultural heritage and many religious and natural tourist spots. Tourism development not only attracts tourists provides them with recreation and generates revenue for the government it also creates employment opportunities around the tourist spots. It has the potential to generate employment for all kinds of people – the lower-income group, the middle-income group, or the higher-income group. Development of a tourist spot and footfall of tourists offers employment opportunities through roadways- buses, autorickshaws, railway platforms, and airways. It creates job opportunities for people involved in hotels and restaurants. A rise in visitors leads to an increased income for people around that area or city.  It leads to an increase in the demand for food, vegetables, fruits, garments, groceries, etc. Visitors spend on shopping for ethnic goods, handicrafts, artificial jewellery and other local products. Altogether a developed tourism industry offers employment opportunities to the people and increases their income. In the last two decades, there has been significant development in roadways and electricity facilities in the State. Tourism in Bihar is developing as an Industry but the pace is very slow, the State has to travel a long road in this area. The State has immense potential for tourism development which has not been explored optimally. This paper analyses the prospects of increasing employment opportunities in Bihar through a developing tourism industry in the State.
Poligami dalam Negara-Negara Islam
Authors: Ambarayadi Bian , Patodongi Andi Molawaliada
Published: May 2024

Polygamy is a problem faced by contemporary society that is considered discrimination against women. Since the beginning of the 20th century, there has been a phenomenon of family law reform in several countries where the majority of the population is Muslim. These countries have reformed Islamic law in family law, triggered by various factors, including political, socio-cultural, economic, and others. This renewal of Islamic law is a new interpretation, where some countries collaborate between Western legal rules and Islamic law. This research aims to study polygamy regulations in nine countries, namely Indonesia, Malaysia, Pakistan, Egypt, Morocco, Jordan, Syria, Turkey, and Tunisia. The method used in this research is a comparative approach to examine the rules of polygamy in the nine countries that are comparing regulations to see the differences and similarities in the rules of polygamy in each country so it can be described according to the group. The results of the discussion show that polygamy in Ulama's view is permissible, and polygamy in 9 Islamic countries can grouped into two, namely, countries that allow polygamy and countries that prohibit polygamy.
Comparing distinct soil test methods for available nitrogen, phosphorus and potassium for groundnut (Arachis hypogaea L.) and wheat (Triticum aestivum L.) grown in North Western India
Authors:   G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India, SHRIVASTAV AKSHAY
Published: May 2024

An experiment was conducted during 2020-21 and 2021-22 in the tarai region of Uttarakhand in order to find simple, economical, effective, and plant uptake correlated soil test methods for determining the available nitrogen, phosphorous, and potassium. Before sowing of groundnut and wheat, soil samples were collected to evaluate available nitrogen, phosphorus, and potassium soil test methods. Wet oxidation was used for organic carbon, alkaline potassium permanganate (KMnO4) was used for mineralizable nitrogen, Olsen's-P, ammonium bicarbonate-diethylene triamine penta acetic acid (AB-DTPA), Mehlich-1 and Morgan-P were used to extract phosphorus (P), and ammonium acetate (NH4OAc), ammonium bicarbonate-diethylene triamine penta acetic acid (AB-DTPA), Mehlich-1 and Morgan-K were used to extract potassium (K). The suitability of these methods for various soil nutrients was assessed by comparing R2 values (coefficients of determination) derived through regression analysis. The results showed that the R2 values of the derived equations by using different combinations of soil test methods to determine available N, P, and K in soil were highly significant in both crops. Superior R2 value for groundnut (0.853**) was observed with the combination of alkaline KMnO4, Olsen’s P, Mehlich-K and for wheat (0.515**) the combination of alkaline KMnO4, Mehlich-P, NH4OAc–K. It found that these combinations are more superior to other methods and more promising.
Assessing the physico-chemical and biological properties of soil under different land use types in southern transect of Bengaluru, Karnataka-India
Authors:   Department of Soil Science and Agricultural Chemistry UAS, GKVK Bengaluru- 65 Karnataka, KUNTOJI ALTAF
Published: May 2024

Soil is key resources upon which the functioning of all biological land use depends, and the most important component of sustainable agriculture with this view the study was conducted to assess physicochemical and biological properties of soil under different land use types in southern transect of Bengaluru. Fifty soil samples were collected from each land use system viz agriculture, horticulture, mulberry and plantation land use. The soil was examined for various physico-chemical and biological properties including sand, silt, clay, soil pH, organic carbon (OC), electrical conductivity (EC), available nitrogen (N), phosphorus (P) and potassium (K), exchangeable calcium (Ca) and magnesium (Mg), sulphur (S), micronutrients (Zn, Fe, Mn, Cu and B) and heavy metals (Cd, Cr, Ni and Pb) and dehydrogenase activity (DHA). The results of the experiment reveled that soil pH varies from strongly acidic (4.23) to strongly alkaline (8.56), low (0.39 dS m-1) to high (0.88 dS m-1 ) EC content. Whereas OC content under different land use systems was in the medium range. The significantly higher soil OC, available N, P2O5 and K2O recorded in agriculture land use. The exchangeable Ca (10.71 c mol (p+) kg-1) and Mg (7.96 c mol (p+) kg-1) recorded significantly higher in agriculture land use. Plantation land use marked significantly higher Fe (12.99 ppm) and Mn (8.51 ppm) contents followed by mulberry (12.16 ppm and 8.23 ppm), Whereas Zn and B were found high in agriculture land use system (0.80 ppm and 0.85 ppm) compare to other land use systems. Heavy metals (Cr, Pb and Ni) were found nonsignificant. Whereas Cd was found significantly different among the land-use system and found high in horticulture land use system (0.049 ppm). Conclusively, land use change affects soil physico-chemical and biological properties.
Electricity Demand, Forecasting the Peaks: Development and Implementation of C-EVA Method
Authors: Theodorou Petros , Christopoulos Demetris Theodoros
Published: May 2024

Price spikes in electricity markets are very frequent, posing tremendous burden on household income and on manufacturing cost. Electricity demand (load) can be divided in two parts, energy (MWh) and peak (MW) and most of time peak is responsible for the price spikes. Literature review while devoting most of the discussion to energy, lags in the investigation of peak. In this research, a model for peak demand analysis and forecasting is developed. The model is based on a portfolio of cluster and extreme value analysis (C-EVA) methods using unit invariant knee,  extremum distance estimator, and weighted scale load innovations for the optimal determination of clusters and the daily peaks divulgence. The C-EVA method consists of the Clustering part for optimal number of clusters determination and classification of day and month of peak, and the part of Extreme Value Analysis for computation of the statistical confidence interval for the load maxima. C-EVA after using all the currently available load maxima, estimates statistically the expected worst-case scenario for peaks of loads. Load peaks will be determined by EVA based on an estimated bimodal distribution while a signaling method will prompt the probability of extremes. The added value of the proposed method is that does not reject the extreme values as most methodologies do. Extreme Value Analysis for maxima and minima provide estimators for highest and lowest expected hourly load, while giving the confidence interval of the return level using an optimization method for the selection of a rolling time window, as the return period. It was found that distributed generation of renewables create a camel effect on the load peaks which increases sharpness. The proposed methodology solved this issue while opening the ground for future research for the role of storage, batteries as well as for virtual power plants as an integrated portfolio of renewables generation.
 
Received: 18 December 2023 | Revised: 18 February 2024 | Accepted: 19 May 2024
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
The database that supports the findings of this study will be made available by the authors upon request only in a specific Excel format.
 
Author Contribution Statement
Petros Theodorou and Demetris Theodoros Christopoulos: Conceptualization, Methodology, Software, Validation, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Supervision, Project administration.
LACTATE EFFECTS ON MUSCLE REGENERATION IN VIVO AND IN VITRO MODELS: A SYSTEMATIC REVIEW
Authors:   Federal University of Paraná, Ferreira Matos Thiago , Casagrande Carli Maria Eduarda ,   Federal University of Paraná, de Moraes Junior Frederico Bento ,   Federal University of Paraná, Abreu de Lima Valderi ,   Federal University of Paraná, Mota Jorge ,   University of Porto, Faculty of Sport, Research Centre in Physical Activity, Leite Neiva ,   Federal University of Paraná,   University of Porto, Faculty of Sport, Research Centre in Physical Activity, Health and Leisure
Published: May 2024

Introduction: Lactate is a substance that, over the years, has been responsible for numerous effects, mainly linked to muscle fatigue, being recently highlighted in systemic processes and muscle regeneration, which still has many points to be clarified, one of them being the participation of lactate in this process. Objective: Verify the effect of lactate on muscle recovery in in vivo and in vitro models. Methods: The search was conducted in five databases (16 June 2022) (PROPERO nº CRD42020209324), using the search words in English and Portuguese: ‘lactate’, ‘lactic acid’, ‘muscle regeneration’, ‘MyoD protein’, and ‘myogenin’. We included experimental and in vitro studies that investigated the use of lactate in relation to muscle (all species and both sexes – males and females). The methodological quality was assessed by a specific questionnaire for in vitro and in vivo studies. Results: Eight articles were selected, of which three studies were found exclusively in vitro, one exclusively in animal models, and four studies with in-vitro models and animal models. Three studies scored overall methodological quality above 90%, another three between 80-90% and two between 70-75%. Both types of studies showed results that may point to the mechanism by which lactate acts in the proliferation and differentiation of myoblasts, either by the action of myogenic regulatory factors (MRFs) or by the actions in the metabolism of these cells. Conclusion: The lactate presence in myoblasts strongly suggests a correlation with the expression of regulatory molecules during muscle regeneration. Future studies must investigate this correlation to advance our understanding of the regulatory mechanisms involved in this process
PLATAFORMAS DIGITAIS DE EXERCÍCIO, ATIVIDADE FÍSICA E COMPORTAMENTO SEDENTÁRIO NA PANDEMIA DE COVID-19
Authors:   Universidade de Santo Amaro, Pereira Lima Renata , Melo Neves Lucas ,   Universidade de Santo Amaro,   Universidade de São Paulo, Faculdade de Medicina, FMUSP,   Grupo de Pesquisa e Laboratório de Atividade Física e Saúde Mental-  LAFISAM, Bonfim do Nascimento Rafael ,   Universidade de Santo Amaro, Programa de Pós-Graduação em Ciências da Saúde,   Grupo de Pesquisa e Laboratório de Atividade Física e Saúde Mental-  LAFISAM,, Gil Saulo ,   Universidade de Santo Amaro, Programa de Pós-Graduação em Ciências da Saúde,   Universidade de São Paulo, Faculdade de Medicina, FMUSP, de Oliveira Pinheiro Bruno ,   Universidade de Santo Amaro
Published: May 2024

Introdução: A pandemia de Covid-19 promoveu o isolamento social e a consequente redução da atividade física moderada e vigorosa (AFMV) e aumento do comportamento sedentário (CS). Como estratégia para alterar tais alterações na AFMV e CS, as plataformas digitais para exercícios (PDE) tornaram-se mais populares durante a pandemia da COVID-19. Objetivo: Verificar se houve diferenças na atividade física (tempo de caminhada e AFMV) e CS (dias de semana, de final de semana e toda semana) entre mulheres que usaram PDE ou que não usaram (Sem PDE) durante a pandemia. Métodos: Esta pesquisa foi um estudo transversal. Mulheres maiores de 18 anos de todas as regiões do Brasil e todas as unidades federativas foram convidadas a participar deste estudo por meio de link enviado via e-mail e redes sociais. A participação ocorreu por meio do preenchimento dos questionários online [Características Demográficas, atividade física e CS (Questionário Internacional de Atividade Física - IPAQ)]. O IPAQ é uma ferramenta amplamente utilizada e validada para a população brasileira e apresenta altas correlações com medidas diretas de atividade física. Resultados: Responderam ao questionário 2.385 mulheres (predominância de mulheres solteiras, ensino superior incompleto e renda mensal <US$450). Nosso principal achado foi que o grupo PDE durante a pandemia de COVID-19 teve mais (p<0,0001) tempo de caminhada (minutos por semana) [PDE: 90 (30-180) vs. sem PDE: 40 (0-120), e AFMV [PDE: 180 (60-420) vs. sem PDE: 100 (0-320). Além disso, diferenças (p<0,0001) no CS durante a semana (horas por dia) [PDE: 5 (2-7) vs. sem PDE: 6 (3-8)], CS no final de semana [PDE: 5 (2 -8) vs. sem PDE: 6 (3-9)] e CS toda a semana [PDE: 5 (3-7) vs. sem PDE: 6 (4-9)]. Conclusões: Nossos resultados indicam que as mulheres que utilizam PDE apresentam maiores níveis de atividade física e menores CS do que aquelas que não o fazem.
EFFECTS OF RECREATIONAL FUTSAL PROGRAM ON THE QUALITY OF LIFE OF OBESE CHILDREN
Authors:   Universidade Federal do Rio Grande do Sul, Escola de Educação Física, Fisioterapia e Dança, Dertzbocher Feil Pinho Carolina , Donida Chedid Lisboa Salime ,   Universidade Federal do Rio Grande do Sul, Escola de Educação Física, Fisioterapia e Dança, Boufleur Farinha Juliano ,   Hospital Escola da Universidade Federal de Pelotas, Empresa Brasileira de Serviços Hospitalares, Barreto Schuch Felipe ,   Departamento de Métodos e Técnicas Desportivas, Universidade Federal de Santa Maria,   Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro,   Faculty of Health Sciences, Universidad Autónoma de Chile, dos Santos Cunha Giovani ,   Universidade Federal do Rio Grande do Sul, Escola de Educação Física, Fisioterapia e Dança
Published: May 2024

Introduction: Childhood obesity is considered the most prevalent chronic disease in the child population, impacting the early onset of associated diseases. These subjects are more susceptible to psychological problems and reduced quality of life, increasing depression rates both in childhood and in adult life. Objective: To verify the effect of recreational futsal programs on the quality of life of overweight and obese children. Methodology: Thirteen overweight and obese boys aged 8-12 years participated in a 12-week recreational futsal program composed of ~80-minute sessions two times a week at an intensity greater than 80% of the maximum heart rate. Quality of life was assessed using the PedsQL 4.0 questionnaire, which assesses physical, emotional, social, and school issues. Results: No significant differences were found for anthropometric variables (P>0.05). The intervention improved the emotional dimension (68.7 ± 15.9 vs. 79.1 ± 18; P=0.03) in overweight and obese boys. Regarding the social dimension (64.4 ± 13.7 vs. 63.7 ± 23.5; P>0.05), physical (68.3 ± 24.6 vs. 75.5 ± 18.7, P>0.05), and school (71.1 ± 22.8 vs.: 72.2 ± 24.2, P>0.05) dimensions, not statistically differences were found (P>0.05). Conclusion: The recreational futsal program was effective in improving the quality of life in the emotional dimension of overweight and obese children.
EFEITOS DO PROGRAMA RECREATIVO DE FUTSAL NA QUALIDADE DE VIDA DE CRIANÇAS OBESAS
Authors:   Universidade Federal do Rio Grande do Sul, Escola de Educação Física, Fisioterapia e Dança, Dertzbocher Feil Pinho Carolina , Donida Chedid Lisboa Salime ,   Universidade Federal do Rio Grande do Sul, Escola de Educação Física, Fisioterapia e Dança, Boufleur Farinha Juliano ,   Hospital Escola da Universidade Federal de Pelotas, Empresa Brasileira de Serviços Hospitalares, Barreto Schuch Felipe ,   Departamento de Métodos e Técnicas Desportivas, Universidade Federal de Santa Maria,   Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro,   Faculty of Health Sciences, Universidad Autónoma de Chile,   Universidade Federal do Rio Grande do Sul, dos Santos Cunha Giovani ,   Universidade Federal do Rio Grande do Sul, Escola de Educação Física, Fisioterapia e Dança
Published: May 2024

Introdução: A obesidade infantil é considerada a doença crônica mais prevalente na população infantil, impactando no aparecimento precoce de doenças associadas. Esses sujeitos estão mais suscetíveis a problemas psicológicos e redução da qualidade de vida, aumentando os índices de depressão tanto na infância quanto na vida adulta. Objetivo: Verificar o efeito de um programa recreativo de futsal na qualidade de vida de crianças com sobrepeso e obesidade. Metodologia: Treze meninos com sobrepeso e obesidade com idade entre 8 e 12 anos participaram de um programa recreativo de futsal durante 12 semanas, composto por, aproximadamente, 80 minutos por sessão e frequência semanal de duas vezes por semana. A intensidade foi superior a 80% da frequência cardíaca máxima. A qualidade de vida foi avaliada por meio do questionário PedsQL 4.0, que avalia questões nas dimensões física, emocional, social e escolar. Resultados: Não foram encontradas diferenças significativas para as variáveis antropométricas (P>0,05). A intervenção melhorou a dimensão emocional (68,7 ± 15,9 vs. 79,1 ± 18; P=0,03) em meninos com sobrepeso e obesidade. Quanto à dimensão social (64,4 ± 13,7 vs. 63,7 ± 23,5; P>0,05), física (68,3 ± 24,6 vs. 75,5 ± 18,7, P>0,05) e escolar (71,1 ± 22,8 vs.: 72,2 ± 24,2, P> 0,05), não foram encontradas diferenças estatísticas (P>0,05). Conclusão: O programa recreativo de futsal foi eficaz para melhorar a qualidade de vida na dimensão emocional de crianças com sobrepeso e obesidade.
The ‘place’ and the ‘otherness’ through the eyes of a restaurantscape
Authors: Fusté-forné Francesc
Published: May 2024

Within a growing relevance of food in shaping cities’ profiles, this paper discusses the glocalized food landscape from the perspective of the city of Inverness, Scotland. Based on the analysis of the restaurantscape in the city center, the research discusses the (dis)connection between place and food and how this informs culinary cosmopolitanism as a driver for urban food tourism management and marketing.
Особенности проведения государственных закупок медицинских продуктов
Authors: Amirova M.A.
Published: May 2024

The pharmaceutical market in Kazakhstan is one of the most developing and at the same time difficult to regulate, since it solves not only the problem of providing state organizations with goods, but also performs the social functions of providing citizens with the state. The article presents an analysis of the market of medicines in the market of Kazakhstan from the standpoint of the formation of relationships within the framework of public procurement. At the same time, the problem of the formation of the drug market was revealed - the predominance of imported drugs, the ratio of domestic and imported drugs in 2020 was 26.3% and 73.7%, respectively. At the same time, the question of the quality of imported goods arises. On the basis of the analysis, the main problems and ways of their solution within the framework of the new legislation have been formed.

Рынок лекарственных средств в Казахстане является одним из наиболее развивающихся и в то же время сложно регулируемым, поскольку решает не просто задачи обеспечения государственных организаций товарами, но и выполняет социальные функции обеспечения государством граждан. В статье представлен анализ рынка лекарственных средств на рынке Казахстана с позиций формирования взаимоотношений в рамках государственных закупок. При этом выявлена проблема формирования рынка лекарственных средств- преобладание лекарств импортного производства, соотношение отечественных и импортных лекарств составило в 2020 году 26,3% и 73,7% соответственно. При этом остро встает вопрос о качестве товаров импортного производства. На основе анализа сформированы основные проблемы и пути их решения в рамках нового законодательства.

Қазақстандағы фармацевтикалық нарық - бұл дамып келе жатқан және сонымен бірге оны реттеу қиын, өйткені ол мемлекеттік ұйымдарды тауарлармен қамтамасыз ету мәселесін шешіп қана қоймайды, сонымен қатар азаматтарды мемлекетпен қамтамасыз етудің әлеуметтік функцияларын орындайды. Мақалада Қазақстан нарығындағы дәрі-дәрмектер нарығына мемлекеттік сатып алу шеңберінде қатынастарды қалыптастыру тұрғысынан талдау жасалған. Бұл ретте дәрі -дәрмек нарығының қалыптасу проблемасы ашылды - импорттық дәрілердің басымдығы, отандық және импорттық дәрілік заттардың қатынасы 2020 жылы сәйкесінше 26,3% және 73,7% құрады. Бұл ретте импорттық тауарлардың сапасы туралы мәселе туындайды. Талдау негізінде негізгі мәселелер мен оларды жаңа заңнама шеңберінде шешу жолдары қалыптасты.
Horeca секторы: интернет-дүкендер тарату логистикасы арнасы ретінде
Authors: Муханбетова А.А.
Published: May 2024

В данной статье рассматриваются характеристики сектора Horeca, включающая в себя сегмент сферы услуг гостеприимства и общепита. Как и во всем мире, сектор Horeca является важной отраслью для Казахстана. Приведенные статистические данные Комитета статистики при Министерстве национальной экономики подтверждают это. Данная отрасль должна получить свое дальнейшее развитие, и в этом случае Интернет-магазины рассматриваются как инструмент для дальнейшего роста продаж в секторе В2В, они выступают эффективным каналом распределительной логистики, позволяющие довести готовый товар до потребителей. Успех интернет-магазинов России не только у себя на родине, но и на территории Казахстана, заставляет задуматься о необходимости выхода интернет торговли Казахстана на новый уровень.

Бұл мақалада Horeca секторының мәселелері қарастырылады, оның ішінде қонақжайлылық және тамақтану қызметтері сегменті бар. Бүкіл әлемдегідей, Horeca секторы да Қазақстан үшін маңызды сала болып табылады. Ұлттық экономика министрлігі жанындағы Статистика комитеті ұсынған статистикалық мәліметтер осыны растайды. Бұл сала өзінің одан әрі дамуын алуы керек, және бұл жағдайда интернет-дүкендер B2B секторындағы сатылымның одан әрі өсу құралы ретінде қарастырылады, олар тұтынушыларға дайын өнімді жеткізуге мүмкіндік беретін тарату логистикасының тиімді арнасы ретінде әрекет етеді. Ресейдегі ғана емес, сонымен қатар Қазақстандағы ресейлік интернет-дүкендердің жетістігі адамды онлайн-сауданың жаңа деңгейге көтерілу қажеттілігі туралы ойлауға мәжбүр етеді.

This article examines the issues of the Horeca sector, which includes the segment of the hospitality and catering services sector. As in the rest of the world, the Horeca sector is an important industry for Kazakhstan. The statistical data presented by the Statistics Committee under the Ministry of National Economy confirm this. This industry should receive its further development, and in this case, online stores are seen as a tool for further growth in sales in the B2B sector, they act as an effective distribution logistics channel that allows you to bring the finished product to consumers. The success of Russian online stores, not only in Russia, but also in Kazakhstan, makes one think about the need for Kazakhstan's online commerce to reach a new level.
Pengintegrasian Sistem BLU-E Dan Aplikasi Ferizy Sebagai Mitigasi Kendaraan Over Dimension Over Load (ODOL) Di Pelabuhan Penyebrangan Merak
Authors: Ahmad Baehaki  , Johannes Valentino Sinaga  , Ghufrillah Arma Danti  , Putri Ainiyyah Hafizha
Published: May 2024

This study proposes integration between the BLU-e (Electronic Test Pass Proof) system and the Ferizy application to mitigate Over Dimension Over Load (ODOL) vehicles at the Merak Crossing Port. ODOL can endanger the safety of passengers and drivers. The merger of the two systems aims to identify vehicles that violate the dimensions and permitted cargo and prevent them from entering ships at the port. This study explains the concept of ODOL, dimensional and payload limitations, and the importance of vehicle weighing. The proposed method involves inputting class and vehicle class data into the Ferizy app during ticket purchase, then cross-checking with BLU-e data and physical inspection by officers. ODOL vehicles will be detected and prohibited from using crossing services while being warned. This integration is expected to improve security and compliance with ODOL regulations at the Merak Crossing Port.
Anatomy of an AI-powered malicious social botnet
Authors: Yang Kaicheng , Menczer Filippo
Published: May 2024

Large language models (LLMs) exhibit impressive capabilities in generating realistic text across diverse subjects. Concerns have been raised that they could be utilized to produce fake content with a deceptive intention, although evidence thus far remains anecdotal. This paper presents a case study about a Twitter botnet that appears to employ ChatGPT to generate human-like content. Through heuristics, we identify 1,140 accounts and validate them via manual annotation. These accounts form a dense cluster of fake personas that exhibit similar behaviors, including posting machine-generated content and stolen images, and engage with each other through replies and retweets. ChatGPT-generated content promotes suspicious websites and spreads harmful comments. While the accounts in the AI botnet can be detected through their coordination patterns, current state-of-the-art LLM content classifiers fail to discriminate between them and human accounts in the wild. These findings highlight the threats posed by AI-enabled social bots.
Cristaux liquides
Authors: Pieranski Pawel , Godinho Maria Helena
Published: May 2024

L’ouvrage Cristaux liquides : nouvelles perspectives porte principalement sur les phases nématiques et cholestériques. Il traite d’abord de l’interaction entre lumière et défauts topologiques, puis examine différents effets électrocinétiques non linéaires permettant de déplacer des particules sous champ électrique alternatif ainsi que la dynamique anisotrope de bactéries flagellées, des phénomènes rendus possibles par la présence de l’ordre orientationnel.Il analyse également les effets thermomécaniques et thermohydrodynamiques d’Akopyan et Zel’dovich, lesquels ne sont pas directement responsables de la rotation Lehmann des gouttes cholestériques comme on l’a cru pendant longtemps.Il expose enfin les propriétés remarquables de cunéitropisme, rhéotropisme et électrotropisme de la texture furcelle nématique avant d’introduire le concept d’émergence de chiralité spontanée dans les phases nématiques composées de molécules achirales.
Simultaneous organic aerosol source apportionment at two Antarctic sites reveals large-scale and ecoregion-specific components
Authors: Paglione Marco , Beddows David C. S. , Jones Anna , Lachlan-Cope Thomas , Rinaldi Matteo , Decesari Stefano , Manarini Francesco , Russo Mara , Mansour Karam , Harrison Roy M. , Mazzanti Andrea , Tagliavini Emilio , Dall'Osto Manuel
Published: May 2024

Abstract. Antarctica and the Southern Ocean (SO) are the most pristine areas of the globe and represent ideal places to investigate aerosol–climate interactions in an unperturbed atmosphere. In this study, we present submicrometer aerosol (PM1) source apportionment for two sample sets collected in parallel at the British Antarctic Survey stations of Signy and Halley during the austral summer of 2018–2019. Water-soluble organic matter (WSOM) is a major aerosol component at both sites (37 % and 29 % of water-soluble PM1, on average, at Signy and Halley, respectively). Remarkable differences between pelagic (open-ocean) and sympagic (influenced by sea ice) air mass histories and related aerosol sources are found. The application of factor analysis techniques to series of spectra obtained by means of proton-nuclear magnetic resonance (H-NMR) spectroscopy on the samples allows the identification of five organic aerosol (OA) sources: two primary organic aerosol (POA) types, characterized by sugars, polyols, and degradation products of lipids and associated with open-ocean and sympagic/coastal waters, respectively; two secondary organic aerosol (SOA) types, one enriched in methanesulfonic acid (MSA) and dimethylamine (DMA) and associated with pelagic waters and the other characterized by trimethylamine (TMA) and linked to sympagic environments; and a fifth component of unclear origin, possibly associated with the atmospheric aging of primary emissions. Overall, our results strongly indicate that the emissions from sympagic and pelagic ecosystems affect the variability in the submicrometer aerosol composition in the study area, with atmospheric circulation establishing marked latitudinal gradients only for some of the aerosol components (e.g., the sympagic components) while distributing the others (e.g., pelagic and/or aged components) both in maritime and inner Antarctic regions.
Phosphomonoesterase and phosphodiesterase activities in the eastern Mediterranean in two contrasting seasonal situations
Authors: Van Wambeke France , Conan Pascal , Pujo-Pay Mireille , Taillandier Vincent , Crispi Olivier , Pavlidou Alexandra , Nunige Sandra , Didry Morgane , Salmeron Christophe , Pulido-Villena Elvira
Published: May 2024

Abstract. Hydrolysis of dissolved organic phosphorus by marine planktonic microorganisms is a key process in the P cycle, particularly in P-depleted, oligotrophic environments. The present study assessed spatiotemporal variations in phosphomonoesterase (PME) and phosphodiesterase (PDE) activities using concentration kinetics in the eastern Mediterranean Sea in two contrasting situations: the end of winter (including a small bloom period) and autumn. The distribution and regulation of the maximum hydrolysis rate (Vm) and half-saturation constant (Km) of both ectoenzymes were assessed in relation to the vertical structure of the epipelagic layers. PME reached its maximum activities (Vm) after the addition of 1 µM MUF-P (4-methylumbelliferyl phosphate), whereas, for PDE, it was necessary to add up to 50 µM bis(4-methylumbelliferyl)phosphate (bis-MUF-P) to reach saturation state. On average, the Km of PDE was 33 ± 25 times higher than that of PME. The Vm of PME and Vm of PDE were linearly correlated. Conversely to the Km values, Vm values were on the same order of magnitude for both ectoenzymes, with their ratio (Vm PME : Vm PDE) ranging between 0.2 and 6.3. Dissolved organic phosphorus (DOP) and the phosphomonoesterase hydrolysable fraction of DOP explained most of the lack of variability in Vm PME and Vm PDE. On the contrary, Vm of both phosphohydrolase enzymes was inversely correlated to the concentration of dissolved inorganic phosphorus. The particular characteristics of concentration kinetics obtained for PDE (saturation at 50 µM, high Km, high turnover times) are discussed with respect to the possible unequal distribution of PDE and PME among the size continuum of organic material and accessibility of phosphodiesters.
GNNWR: An Open-Source Package of Spatiotemporal Intelligent Regression Methods for Modeling Spatial and Temporal Non-Stationarity
Authors: Yin Ziyu , Ding Jiale , Liu Yi , Wang Ruoxu , Wang Yige , Chen Yijun , Qi Jin , Wu Sensen , Du Zhenhong
Published: May 2024

Abstract. Spatiotemporal regression is a crucial method in geography for discerning spatiotemporal non-stationarity in geographical relationships, which has found widespread application across diverse research domains. This study implements two innovative spatiotemporal intelligent regression models, namely geographically neural network weighted regression (GNNWR) and geographically and temporally neural network weighted regression (GTNNWR), integrating the spatiotemporal weighted framework and neural networks. Demonstrating superior accuracy and generalization capabilities in large-scale data environments compared to traditional methods, these models have emerged as prominent tools. To facilitate the seamless application of GNNWR and GTNNWR in addressing spatiotemporal non-stationary processes, a Python-based package, GNNWR, has been developed. This article details the implementation of these models and introduces the GNNWR package, enabling users to efficiently apply these cutting-edge techniques. Validation of the package is conducted through two case studies. The first case involves the verification of GNNWR using air quality data from China, while the second employs offshore dissolved silicate concentration data from Zhejiang Province to validate GTNNWR. The results of the case studies underscore the effectiveness of the GNNWR package, yielding outcomes of notable accuracy. This contribution anticipates a significant role for the developed package in supporting future research that leverages big data and spatiotemporal regression techniques.
Non-invasive imaging techniques for diagnosis of pelvic deep endometriosis and endometriosis classification systems: an International Consensus Statement
Authors: Condous G , Gerges B , Thomassin-Naggara I , Becker C , Tomassetti C , Krentel H , van Herendael B.J. , Malzoni M , Abrao M.S. , Saridogan E , Keckstein J , Hudelist G ,   Intersociety Consensus Group
Published: May 2024

The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) and International Deep Endometriosis Analysis (IDEA) group, the European Endometriosis League (EEL), the European Society for Gynaecological Endoscopy (ESGE), the European Society of Human Reproduction and Embryology (ESHRE), the International Society for Gynecologic Endoscopy (ISGE), the American Association of Gynecologic Laparoscopists (AAGL) and the European Society of Urogenital Radiology (ESUR) elected an international, multidisciplinary panel of gynecological surgeons, sonographers and radiologists, including a steering committee, which searched the literature for relevant articles in order to review the literature and provide evidence-based and clinically relevant statements on the use of imaging techniques for non-invasive diagnosis and classification of pelvic deep endometriosis. Preliminary statements were drafted based on a review of the relevant literature. Following two rounds of revisions and voting orchestrated by chairs of the participating societies, consensus statements were finalized. A final version of the document was then resubmitted to the society chairs for approval.

Twenty statements were drafted, of which 14 reached strong and three moderate agreement after the first voting round. The remaining three statements were discussed by all members of the steering committee and society chairs and rephrased, followed by an additional round of voting. At the conclusion of the process, 14 statements had strong and five statements moderate agreement, with one statement left in equipoise. This consensus work aims to guide clinicians involved in treating women with suspected endometriosis during patient assessment, counselling and planning of surgical treatment strategies.
Edad, envejecimiento y edadismo en Julieta (2016) de Pedro Almodóvar
Authors: Gómez Gómez Agustín
Published: May 2024

Analizamos Julieta (Pedro Almodóvar, 2016) desde su temática etaria. Hay tres personajes mayores: un hombre que se suicida, una ama de llaves y el padre de la protagonista. En paralelo asistimos al envejecimiento de tres personajes, dos que se jubilan y un tercero, la protagonista, que pasa de una juventud extrovertida y alegre a una mujer madura y psicológicamente abatida por la pérdida de su marido y la huida de su hija, hechos de los que se culpabilizará. Con estos presupuestos, Almodóvar establece una serie de contrastes con las edades, rompe algún estereotipo edadista y mantiene algunas de las características de sus personajes. Tenemos en cuenta que se trata de una libre adaptación de tres relatos de Alice Munro.
Narrativas sobre la Agenda 2030 en la Asamblea de Madrid
Authors: López Frías Claudia
Published: May 2024

La Asamblea de Madrid, como foro público, tiene el deber y obligación, por un lado de reflejar el sentir de la ciudadanía y, por otro de trabajar por el bien común para mejorar la vida de los ciudadanos madrileños. El presente trabajo recoge cuál es el criterio de nuestros políticos regionales respecto a la Agenda 2030, y los Objetivos de Desarrollo Sostenible con el objetivo de saber si existe un entendimiento sobre la envergadura de la emergencia climática y la necesidad de comunicar e implementar dichos objetivos.
Presence and framing of climate change in the digital press of Uruguay
Authors: Gari Juan Manuel , Gómez Victoria , Pérez Álvarez Álvaro
Published: May 2024

Cerca del 80% de los uruguayos perciben una baja presencia del cambio climático (CC) en la prensa (PNUD Uruguay, 2021). Este artículo analiza cómo el periodismo digital de Uruguay informa y encuadra el CC e identifica oportunidades para mejorar la cobertura periodística del tema y de la Política Nacional de Cambio Climático. El análisis de contenido revela, entre otros hallazgos, falta de énfasis en explicaciones científicas y posibles soluciones tecnológicas a los problemas del CC, medidas políticas desatendidas por los medios y un uso casi inexistente de contenidos audiovisuales para informar. El artículo concluye con recomendaciones sobre cómo las autoridades políticas y los medios pueden comunicar sobre el CC para que los ciudadanos comprendan el fenómeno y su relación con él.
Trust, Value, Price Fairness: Boosting Loyalty in Eco Hair Care
Authors: Dinanti Altisya Putri , Suhud Usep , Krissanya Nofriska
Published: May 2024

The purpose of this research is to determine the influence of trust, perceived value, perceived price fairness, and customer satisfaction on customer loyalty to environmentally friendly hair care products. The research method uses a quantitative research design by distributing questionnaires. A total of 254 respondents were sampled using purposive sampling technique. The research objects in this study were respondents aged 18-60 years in DKI Jakarta and had purchased environmentally friendly hair care products at least three times in the last year. This research uses SPSS version 26 software and SEM (Structural Equation Model) from AMOS software to analyze and process research data. The research results show that: first, trust, perceived value, and perceived price fairness have a positive and significant effect on customer satisfaction. Second, trust, perceived value, and customer satisfaction have a positive and significant effect on customer loyalty. Third, perceived price fairness has no influence on customer loyalty.
MAGNETIC MODIFICATION OF ION EXCHANGE PROCESSES
Authors: Kovtun David , Dushkin Stanislav
Published: May 2024

The method of ion exchange is widely used in modern water supply systems. Ion exchange units are used to correct the mineral composition of water to the required standards; wastewater treatment; desalination and softening of natural waters. Today, there are technical solutions to improve the process of water purification, softening and demineralization. They include: improvement of physical and chemical conditions; intensification of the ion exchange process; use of new ion exchange materials; modification of ion exchange resins; combination with other water treatment methods; modernization of equipment and designs of ion exchange devices. The paper investigates the effect of magnetic modification on the intensification of ion exchange processes during the adjustment of the mineral composition of natural waters. The obtained results demonstrate the influence of the magnetic field on the ion exchange process.
Perspective taking in language: When bodily involvement impacts motion events’ descriptions Auteurs-es Aurelie Barnabé
Authors:   LRL, Université Blaise Pascal, Clermont-Ferrand, Barnabé Aurelie
Published: May 2024

Speakers’ linguistic apprehension of the world tends to be circumscribed by the language they use, a language that mirrors speech habits, structured by lexical and morphosyntactic patterns. To this respect, when structuring the domain of space through language, English verbs and satellites foreground the action and background the purpose (swim across a river), whereas French linguistic features foreground the aim and background the act (traverser la rivière à la nage); both linguistic patterns giving hence precisions on the relationship held between the speaker and his body according to what is preferentially highlighted in the language used. These linguistic patterns illustrate the Talmian typology which opposes satellite-framed languages like English, to verb-framed languages like French. To further investigate this typology, distinguishing phrases structured differently to refer to motion events (Talmy, 2000) according to the type of language used, an experiment soliciting English and French spoken corpora aims at demonstrating whether the affiliation of a language to a specific language type (e.g. English as a satellite-framed language) determines or not the embedding of the language examined to this specific affiliation, once the speech is actually implemented in discursive contexts.
Analysis of the SER/ESTAR opposition based on the origins and evolution of {st} saliencing : a submorphological and enactive approach
Authors:   Aix-Marseille Université, Pagès Stéphan
Published: May 2024

The theory of submorphemic saliencing has tried to show that the notion of « stability » is often expressed in Spanish through words that include the consonantal group {st}. However, this saliencing is the constitutive marker of the verb estar’s paradigm, generally associated with accidental or circumstantial existence with no essentialising projection, as opposed to the verb ser. Taking a diachronic and synchronic approach based on the signifier, this article aims to explain and understand this apparent contradiction, i.e. the systemic and semantic opposition between ser and estar (sedere/stare). The hypothesis defended in this study is that we are faced with a semantic opposition that can also be seen at the level of the signifiers, which are opposed in two different configurations offering an illustrative example of the motivation of the sign.
Multi-infarct stroke secondary to reactive thrombocytosis in a patient with iron deficiency anaemia: A case report
Authors:   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., Manoj Preethy , Derwin Rosemarie ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., Dolan Eamon ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., Moore Zena ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., Patton Declan ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., O Connor Tom ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., Nugent Linda ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland., George Sherly ,   School of Nursing and Midwifery, Royal College of Surgeons in Ireland, St Stephens Green, St Peters, Dublin 2, Ireland.
Published: May 2024

A 47-year-old woman who presented to the hospital with left sided weakness, left sided paraesthesia, ataxic gait, headache, nausea and vomiting was found to have multiple infarct strokes. Her past medical history was significant for iron deficiency anaemia secondary to menorrhagia. Her haemoglobin level on arrival at the hospital was 7.3 gm/dl. Her symptoms improved after blood transfusions and iron infusion. She had low cardiovascular risk factors and her stroke work up was negative. So, it was assumed that her stroke was likely related to reactive thrombocytosis secondary to iron deficiency anaemia.