bluuebunny/crossref_metadata_2025 huggingface dataset:
Біотехнологічний напрямок вирощування пшениці озимої залежно від сівозмінного фактору в умовах Степу України
Authors: Мащенко Ю.В. , Соколовська І.М. , Кулик Г.А.
Published: July 2024

Сучасні умови розвитку аграрного сектору вимагають постійне збільшення обсягів виробництва якісної сільськогосподарської продукції. Особливої актуальності ці питання набувають через глобальні зміни клімату, науково-обґрунтовані підходів до структури посівних площ та систем удобрення, біологізацію землеробства. Тому подальше зростання виробництва пшениці озимої, підвищення її продуктивності та покращення якості зерна потребують постійного вдосконалення та оптимізації технології вирощування на основі новітніх наукових розробок. Метою наших досліджень було встановити залежність рівня врожайності та економічної ефективності вирощування пшениці озимої в сівозмінах короткої ротації з використанням біопрепарату в умовах Північного Степу країни. Польові дослідження проводили протягом 2021-2023 рр. в лабораторії землеробства Інституту сільського господарства Степу НААН. Пшеницю озиму сорту Оранта одеська вирощували в трьох короткоротаційних сівозмінах з насиченням соєю 20%, 40 % та 60 %. Насіння пшениці озимої обробляли біопрепаратом Мікофренд. Обробка насіння препаратом Микофренд сприяла отриманню вищих показників врожайності пшениці озимої по сівозмінах з різним насиченням сої: 60 % – 5,58 т/га, 40 % – 5,98 т/га, 20 % – 6,63 т/га, але достовірну прибавку врожаю за рахунок дії біопрепарату було отримано в сівозмінах, концентрація посівів сої в яких складала 60 % та 40 %. Більш ефективно на урожайність пшениці озимої в умовах Північного Степу України впливав сівозмінний фактор. Найвища економічна ефективність вирощування пшениці озимої була у зерно-паро-просапній сівозміні з насиченням соєю до 20 % з використанням біологічно активного препарату за рентабельності 132,9 %. Більший вплив на отримання додаткового умовно-чистого прибутку мав фактор сівозміни. Максимальна прибавка, 6878 грн/га, була у зерно-паро-просапній сівозміні з насиченням соєю до 20 %. Фактор біопрепарат забезпечував прибавку від 2101 грн/га у зерно-паро-просапній сівозміні з насиченням соєю на 20 % до 3466 грн/га у зерно-просапній сівозміні з насиченням соєю на 60 %.
El estudio analítico del lenguaje
Authors: Alcaraz Romero Víctor Manuel ,   Instituto de Neurociencias, Universidad de Guadalajara
Published: July 2024

El estudio científico del lenguaje requiere un enfoque analítico dirigido a descubrir sus diferentes componentes. Con dicho análisis podremos establecer la función de cada componente y así tener una visión más completa del lenguaje. En esa tarea hemos encontrado las siguientes funciones principales de algunos de los componentes: a) Servir de signos de la realidad. b) Constituir guías de la conducta de hablantes y oyentes. c) Funcionar como estímulos para establecer unidades más complejas del tipo de las oraciones. d) Ayudar al control de la conducta no verbal.
Variáveis que Afetam a Formaçâo de Classes de Estímulos: Estudos sobre Efeitos do Arranjo de Treíno
Authors: de Rose Júlio C. ,   La Universidade Federal de São Carlos, Kato Olivia M. , Thé Ana Paula G. , Kledaras Joanne B. ,   Universidade Federal do Pará,   La Universidade Federal de São Carlos,   The Learning Center, Waltham, Massachusetts
Published: July 2024

O presente ensaio descreve esrudos analisando efeitos de arranjos de treino com um único nódulo e com múltiplos nódulos sobre a formaçâo de classes de equivalencia e transferencia de funçôes discriminativas. Esta análise sugere que o arranjo de treino e o número de nódulos nâo tem um efeito isolado, mas interage de modo complexo com outros parâmetros do procedimento. Alguns estudos mostram maior eficácia de arranjos com um único nódulo em relaçâo a arranjos com múltiplos nódulos. No entanto, mudanças no procedimento de treino de discriminacôes condicionáis e na topografia de respostas de escolha podem tomar os arranjos coro múltiplos nódulos tâo eficazes quanto os arranjos com um único nódulo. Sugere-se que estas variaçôes estâo relacionadas com a topografía de controle de estímulo induzida pelas diferentes variantes de procedimento na linha de base de 'discnminaçâo condicional.
Naturaleza de las propiedades empleadas en el entrenamiento en inclusión y su efecto sobre la solución de silogismos
Authors: Mares C. Guadalupe ,   Universidad Nacional Autónoma de México-Campus Iztacala, Galicia M. Iris Xóchitl , Sánchez V. Alejandra , Pavón F. Susana , González S. Ma. de Jesús ,   Universidad Nacional Autónoma de México-Campus Iztacala,   Universidad Nacional Autónoma de México-Campus Iztacala,   Universidad Nacional Autónoma de México-Campus Iztacala,   Universidad Nacional Autónoma de México-Campus Iztacala
Published: July 2024

El estudio tuvo dos propósitos: 1) promover de manera directa en niños de segundo grado de primaria de escuelas públicas el razonamiento lógico y 2) evaluar el efecto de las propiedades (aparentes vs. no aparentes) involucradas en las tareas de inclusión sobre la ejecución en silogismos abstractos. En la primera fase, se seleccione a 21 niños de segundo grado que resolvieron correctamente tres silogismos o menos de un total de 12. En la segunda fase, los niños se dividieron al azar en tres grupos. Los sujetos del grupo 1 recibieron entrenamiento en tareas de inclusión basadas en propiedades aparentes (color, forma. tamaño, etc.). Los sujetos del grupo 2 recibieron entrenamiento en inclusión basado en propiedades no aparentes. El grupo 3 que funcionó como control, participó en juegos de mesa En la tercera fase, se aplicó nuevamente a todos los niños una prueba de 12 silogismos divididos en: concretos familiares, concretos no familiares y abstractos. Los niños del grupo 1 incrementaron el número de respuestas correctas en los silogismos familiares y no familiares pero no en los abstractos; los niños del grupo 2 incrementaron el número de respuestas correctas en los silogismos familiares, no familiares y en los abstractos; finalmente los niños del grupo control no incrementaron en ningún tipo de silogismos. Además de discutir los resultados en términos de los propósitos explícitamente señalados, se analizan sus implicaciones en el contexto de la discusión sobre las bases organísmicas o ambientales del desarrollo y naturaleza de la relación lenguaje-pensamiento.
Teoría de la conducta: extensiones sobre el desarrollo del comportamiento inteligente
Authors: Varela Julio ,   Universidad de Guadalajara
Published: July 2024

Con base en la formulación que Ribes y López (1985) hacen en relación al comportamiento y los trabajos de Ribes (1981. 1990) sobre el comportamiento inteligente, se describen las categorías del discurso didáctico que favorecen su desarrollo y que consisten en: a) un ejercicio variado y retroalimentado por el agente enseñante; b) describir el desempeño y las condiciones funcionalmente pertinentes; e) describir descripciones de desempeños variados, eficaces y pertinentes: d) describir condiciones en las que se puede aplicar esa regla de desempeño y: e) transmitir el conocimiento a otros. En cada caso, se hace hincapié en las ventajas que tiene un discurso de este tipo para superar la calidad de la educación.
ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ GÃY KÍN THÂN HAI XƯƠNG CẲNG TAY Ở TRẺ EM BẰNG ĐINH NỘI TỦY ĐÀN HỒI
Authors: Đoàn Nguyễn Nhật Tín , Nguyễn Tấn Bảo Ân , Võ Quang Đình Nam , Phan Đức Minh Mẫn , Nguyễn Dương Phi
Published: July 2024

Đặt vấn đề: Gãy thân hai xương cẳng tay là một trong những chấn thương thường gặp ở trẻ em, chiếm tỷ lệ 1-2% trong tổng số các trường hợp gãy xương. Việc điều trị gãy thân hai xương cẳng tay trẻ em đòi hỏi phải lựa chọn phương pháp phù hợp để đảm bảo khả năng liền xương tốt, phục hồi chức năng nhanh chóng và giảm thiểu biến chứng, đặc biệt trẻ em thường đáp ứng tốt với các phẫu thuật ít xâm lấn. Phương pháp đinh nội tủy đàn hồi được giới thiệu lần đầu bởi các phẫu thuật viên tại bệnh viện Nancy, Pháp vào thập niên 1980 đã trở thành một lựa chọn điều trị hiệu quả cho các trường hợp gãy xương dài ở trẻ em.

Đối tượng và Phương pháp nghiên cứu: Nghiên cứu này được thực hiện nhằm đánh giá hiệu quả của phương pháp đóng kín đinh nội tủy đàn hồi trong điều trị gãy thân hai xương cẳng tay ở trẻ em tại bệnh viện Chấn thương Chỉnh hình Thành phố Hồ Chí Minh. Nghiên cứu được thiết kế dưới dạng tiến cứu với cỡ mẫu là 32 bệnh nhi từ 10 đến 15 tuổi với chẩn đoán gãy kín thân hai xương cẳng tay. Các chỉ số lâm sàng và X-quang được ghi nhận trước và sau phẫu thuật. Bệnh nhân được tái khám và đánh giá tình trạng liền xương, biên độ vận động cẳng tay và khuỷu, cùng các biến chứng sau mổ nắn kín.

Kết quả: Thời gian nằm viện trung bình là 3 ngày và thời gian phẫu thuật trung bình là 45 phút. Kết quả nghiên cứu cho thấy tỷ lệ liền xương đạt 100% với thời gian liền xương trung bình là 6 tuần. Biến chứng nhiễm trùng nhẹ (theo phân loại của SSI) xảy ra ở 1 trường hợp (3,1%) và không có trường hợp nào bị di lệch thứ phát. Biên độ vận động cẳng tay và khuỷu tốt đạt 87,5%, trong khi 12,5% còn lại có biên độ vận động trung bình theo tiêu chuẩn Price và Anderson.

Kết luận: Phương pháp điều trị gãy kín thân hai xương cẳng tay ở trẻ em bằng đinh nội tủy đàn hồi đã được chứng minh là hiệu quả và an toàn. Nghiên cứu này cung cấp thêm bằng chứng hỗ trợ cho việc sử dụng rộng rãi phương pháp này trong thực hành lâm sàng.
SOSIALISASI PENTINGNYA LOKASI UMKM PADA GOOGLE MAPS SEBAGAI BENTUK DIGITAL MARKETING
Authors: Yusuf Muhammad , Rahman Zia Urr , Helfenta Helfenta
Published: July 2024

MSMEs are one of the economic activities that support the economic growth of the community in Nagari Tanah Bakali Inderapura. The limited knowledge of MSME owner about the use of technology in running a business that causes the business to be run is still limited in scope. This activity was carried out to inform MSME owners about Google Maps and its benefits, as well as provide assistance in business registration on the feature. This community service activity is carried out in two stages, namely preparation and implementation. Preparations were made to find out the problems faced by MSME owners and prepare pamphlets about the stages of registering on Google Maps. At the implementation stage, socialization was carried out about Google Maps and its uses, as well as accompanying business registration on the feature. The results of the activity show that activities can change the views of MSME owners in utilizing technology, especially Google Maps.
SOSIALISASI KEWIRAUSAHAAN DALAM UPAYA PENINGKATAN UMKM DI NAGARI MUARA INDERAPURA UNTUK MENINGKATKAN PEREKONOMIAN
Authors: Putra Eka , Bustami Yuserizal , Mahabbati Suci , Azhar Azhar , Afrilia Annisa
Published: July 2024

Along with the times, the world of technology is growing, so MSMEs in an economic society must keep up with technological developments to maintain their existence in business and business management, as micro, small, and medium enterprises (MSMEs) play a key role in growth. Indonesian economy. MSMEs account for 85% of the employment rate. In a business, it is necessary to study the business's survival. However, in reality, the community only focuses on the status of working as an employee in a company to earn income. Therefore, cultivating a community with a socialization approach imbued with entrepreneurship is done to help motivate people to run independent businesses. Empowerment refers to the ability of individuals, especially disadvantaged groups, to find productive resources that help them increase their income and participate in development and decision-making processes. The results of this study indicate that the people of Muara Inderapura Village have great potential for village economic development through MSME. Factors supporting community development in the economic field include abundant natural and human resources and strong community participation. While the inhibiting factors are capital, facilities.
Assisted colonisation for ecosystem function: a thought experiment for the British Isles
Authors: Gardner Charlie , Bullock James
Published: July 2024

Climate change is driving the rapid reorganisation of the world’s biota as species shift their ranges to track suitable conditions, however habitat fragmentation and other barriers hinder this adaptive response for species with limited dispersal ability. The translocation of species into newly suitable areas to which they are unable to disperse naturally has been suggested to conserve species threatened by climate change, but has not been widely adopted because the deliberate introduction of non-native species poses invasion risks and runs counter to traditional conservation approaches and philosophies. Using the future of forest ecosystems in the British Isles as a thought experiment, we argue that mass-scale assisted colonisation will be required not to conserve threatened species, but for the maintenance of functional ecosystems themselves. As climate changes, existing forest plant and animal communities of northern Europe will increasingly die out. On the mainland they will be somewhat replaced by analogous species from further south, but in Great Britain this replacement will be limited to a subset of mobile species due to the ocean barrier. As a result, forests there will lack many important component species unless these are actively translocated, will have reduced resilience and adaptive capacity, and will eventually collapse. Given the need for functional ecosystems in a hotter and highly fragmented world, conservationists must shift from trying to prevent change to trying to shape the biotic changes that are now inevitable. We must shift from reactive to proactive approaches in order to facilitate the emergence of robust novel ecosystems.
Scanning the skies for migrants: Conservation-focused opportunities for a pan-European automated telemetry network
Authors: Mitchell Lucy , Brust Vera , Karwinkel Thiemo , Åkesson Susanne , Kishkinev Dmitry , Norevik Gabriel , Szep Tibor , Hedenström Anders , Lagerveld Sander , Helm Barbara , Schmaljohann Heiko
Published: July 2024

Accelerated biodiversity loss during the Anthropocene has destabilised functional links within and between ecosystems. Migratory species that cross different ecosystems on their repeated journeys between breeding and non-breeding sites are particularly sensitive to global change because they are exposed to various, often ecosystem-specific threats. As these bring both lethal and non-lethal population impacts, many migratory species are declining, making this group especially vulnerable to global change. To mitigate their decline, research at a continental and flyway scale is required to adequately monitor changes in the demographic processes of populations and understand the needs of migratory species, during all parts of the annual cycle. The Motus Wildlife Tracking System (Motus) could provide a solution to data gaps that exist particularly for small and migratory species. Motus is an automated telemetry system for animal tracking, which originated in North America. It provides a collaborative network by using the same VHF radio frequency for all tracked individuals, in combination with an individual tag identifier. Motus can provide information on movements made by individuals of the smallest bird and bat, and even larger insect species, thus aiding our understanding of aspects of their migration that could impact demographic parameters. Here we emphasise conservation-focused research opportunities, with a particular lense on European migrant taxa. We highlight examples from the existing network, and identify geographical gaps in the network which need to be filled to track continent-wide movements. We conclude that Motus is a useful tool to produce individual-level migration information for a variety of small-bodied taxa, and that a drive to expand the network will improve its ability to conservation plans for such species.
Precision Pathway Engineering in Plants: Enhancing Crop Resilience and Productivity for Sustainable Agriculture
Authors: Fan Katie
Published: July 2024

Recent advancements in metabolic engineering have opened new avenues for addressing critical challenges in agriculture, nutrition, and sustainability. This study explores innovative strategies for manipulating plant metabolic pathways to enhance crop yield, nutritional value, stress tolerance, and the production of high-value compounds. We present novel findings on improving photosynthetic efficiency, nutrient utilization, and abiotic stress resistance through targeted metabolic interventions. Our research leverages cutting-edge approaches in synthetic biology and multi-gene trait stacking, demonstrating their potential to revolutionize crop improvement. By integrating various omics technologies with advanced computational modeling, we have developed highly precise metabolic engineering designs. We showcase the application of CRISPR/Cas9 and other gene editing techniques in fine-tuning plant metabolism and explore the potential of plants as biofactories for pharmaceutical and industrial compounds. Our work also addresses the regulatory and biosafety considerations of genetically modified crops, providing a balanced perspective on their role in future agricultural systems. This research highlights the transformative impact of metabolic engineering in tackling food security, climate change adaptation, and sustainable production of valuable compounds, while also identifying key challenges and future directions in this rapidly evolving field.
الضمانات المستحدثة لحماية المستهلك في التجارة الإلكترونية
Authors: Mhana Ibraheem Hammood , AL- Mekhlafi Abdullah Mohammed , Zakaria Zalina
Published: July 2024

The growing volume of electronic commerce and the increase in the number of internet users worldwide promotes policymakers in many countries to provide legal guarantees to consumers in e- commerce. This is due to the inability of current general rules to provide this type of protection for them .The purpose of this paper is to examine the right to withdraw from a contract as a legal guarantee to the consumer, to indicate the necessity to adopt this right within the consumer protection legislation and e-commerce legislation in Iraq. The choice to view the product’s provisions are examined too in this paper regarding to the Islamic jurisprudence and Iraqi civil law to indicate the extent of protection that ‘the choice to view’ to the consumer in e-commerce. The paper executes the descriptive analytical and comparative approaches in this research. The findings reveal that consumer in electronic commerce can benefit from the protection that ‘the choice to view’ in Islamic Fiqh (jurisprudence) and Iraqi civil law can achieve. Thus, the consumer has the right to withdraw from a contract after seeing the goods and send it back to the seller. In conclusion, they can be reimbursed according to certain conditions. Iraqi legislator can adopt the right to withdraw from the contract in addition to the choice to view to ensure more protection for the consumer.
Accounting for Beekeeping Products: Current State and Ways of Improvement
Authors: Shulhan Mariia ,   Vinnytsia National Agrarian University, Vinnytsia, Ukraine
Published: July 2024

Today, thanks to the active development of beekeeping on an industrial scale, Ukraine has become one of the largest exporters of honey to the market of EU countries. In this regard, the government is working on introducing EU requirements in the field of beekeeping into Ukrainian legislation to support this positive trend in the development of the industry. However, the main component of information and analytical support for managing beekeeping products production – accounting needs to be updated. The article aims to study the method of accounting for beekeeping products, determine the features of this process, and develop proposals for improving synthetic and analytical accounting at enterprises engaged in beekeeping. It was found that Methodical recommendations on accounting of biological assets and National Accounting Standard 30 "Biological assets" do not allow clear identification of accounting objects by types of beekeeping products, complicating the process of organizing accounting at an agricultural enterprise. To solve this problem, the article defines a list of beekeeping's main, related and by-products and proposes a structure of analytical accounts for their accounting. The production specifics are considered, particularly the stages of work at the apiary in each season. Correctly adjusted synthetic and analytical accounting in beekeeping will allow the accountant to collect the necessary data for making management decisions and compiling various forms of reporting of agricultural enterprises. The structure of analytical accounts by the type of beekeeping products proposed by the author will allow timely monitoring of its presence and movement and contribute to improving apiary management. In addition, the research results can be used to develop methodical recommendations on accounting for beekeeping products.
ОСВІТА ДІТЕЙ З ПОРУШЕННЯМ СЛУХУ В УМОВАХ ВІЙНИ (З ДОСВІДУ ХМЕЛЬНИЦЬКОЇ СПЕЦІАЛЬНОЇ ЗАГАЛЬНООСВІТНЬОЇ ШКОЛИ №33)
Authors: Воробель Галина
Published: July 2024

Педагогічні колективи спеціальних закладів освіти в умовах викликів воєнного часу знаходить рішення, щоб навчати та підтримувати учнів, утілювати актуальні зміни в організації шкільного простору, швидкого реагувати на зміни ситуації, потреби громади тощо. В умовах війни роль спеціальних закладів в освіті дітей з порушеннями слуху, зважаючи на кадровий та матеріальний потенціал, безумовно підвищується. Розвиваються нові напрями роботи, упроваджуються актуальні методики, що зумовлює високу затребуваність таких закладів. Метою статті є висвітлення нагальних проблем організації роботи спеціальних закладів освіти для дітей з порушеннями слуху в умовах воєнного стану в Україні, презентація досвіду роботи Хмельницької спеціальної загальноосвітньої школи №33 в умовах війни. Методи дослідження: аналіз психологічної, педагогічної літератури з проблеми дослідження; аналіз нормативно-правових документів; метод вивчення та узагальнення практичного досвіду роботи спеціальних закладів освіти для дітей з порушеннями слуху; презентація досвіду роботи Хмельницької спеціальної загальноосвітньої школи №33 в умовах війни. Окреслено важливі питання навчання дітей з порушеннями слуху в Україні, виклики, що постали через війну, що потрібно враховувати при організації навчання в умовах воєнного стану (облаштування безпечного середовища в школі, обладнання укриття, організація очного навчання, психосоціальна підтримка учнів та батьків тощо), та які переваги спеціальних закладів освіти для учнів з порушеннями слуху. Представлено питання удосконалення нормативного забезпечення освіти дітей з порушеннями слуху, міждисциплінарної співпраці фахівців, залучення батьків.
НАВЧАННЯ ЧЕРЕЗ ДОСЛІДЖЕННЯ ЯК ОСНОВА ПІДГОТОВКИ ВЧИТЕЛЯ-ЛОГОПЕДА: НА ПРИКЛАДІ ДОСВІДУ НАВЧАННЯ ЗДОБУВАЧІВ В ХАРКІВСЬКОМУ НАЦІОНАЛЬНОМУ ПЕДАГОГІЧНОМУ УНІВЕРСИТЕТІ ІМЕНІ Г. С. СКОВОРОДИ
Authors: Друганова Олена , Коваленко Вікторія , Сінопальнікова Наталія
Published: July 2024

Одним із пріоритетних завдань сучасної логопедії є підготовка компетентних, висококваліфікованих учителів-логопедів для роботи з дітьми з функціональними мовленнєвими освітніми труднощами у міждисциплінарному контексті. У статті розглядаються питання підготовки майбутніх учителів-логопедів до професійної діяльності із застосуванням технології навчання через дослідження в Харківському національному педагогічному університеті імені Г. С. Сковороди.
Мета дослідження – проаналізувати й узагальнити досвід реалізації навчання через дослідження у процесі підготовки майбутніх учителів-логопедів у Харківському національному педагогічному університеті імені Г. С. Сковороди.
Навчання через дослідження сприяє не лише поглибленню теоретичних знань, а й розвитку критичного мислення, практичних навичок, творчої самостійності та професійної компетентності. Одним із шляхів реалізації обраного наукового підходу є технологія «прямого впливу», що передбачає залучення здобувачів до науково-дослідної діяльності в межах студентських наукових гуртків, конференцій, Сковорода-Хабу, олімпіад, тижнів науки, проведення виїзних занять на базі університетських кафедр, впровадження програм внутрішньої та міжнародної академічної мобільності тощо. Технологія «опосередкованого впливу» передбачає осучаснення психодидактичного компонента університетського освітнього середовища, зміну структури вивчення навчальних дисциплін, посилення медико-біологічної складової підготовки, широке застосування інтерактивних методів навчання, впровадження індивідуальних проєктів, оновлення змістового наповнення освітніх компонентів, залучення до освітнього процесу професіоналів-практиків та провідних науковців з інших закладів вищої освіти у формі гостьових лекцій, круглих столів. Важливо забезпечити інтеграцію наукових досліджень в освітній процес, розвиток дослідницьких навичок здобувачів, використання сучасних технологій та дотримання етичних стандартів.
When to interfere with dark matter? The impact of wave dynamics on statistics
Authors: Gough Alex , Uhlemann Cora
Published: July 2024

Ultralight candidates for dark matter can present wavelike features on astrophysical scales. Full wave based simulations of such candidates are currently limited to box sizes of 1–10 Mpc/ h on a side, limiting our understanding of the impact of wave dynamics on the scale of the cosmic web. We present a statistical analysis of density fields produced by perturbative forward models in boxes of 128 Mpc/ h side length. Our wave-based perturbation theory maintains interference on all scales, and is compared to fluid dynamics of Lagrangian perturbation theory. The impact of suppressed power in the initial conditions and interference effects caused by wave dynamics can then be disentangled. We find that changing the initial conditions captures most of the change in one-point statistics such as the skewness of the density field. However, different environments of the cosmic web, quantified by critical points of the smoothed density, appear to be more sensitive to interference effects sourced by the quantum potential. This suggests that certain large-scale summary statistics may need additional care when studying cosmologies with wavelike dark matter.
Reference interval of free light chains ratio in patients with end-stage renal disease on chronic hemodialysis
Authors: Peña Camila , Valjalo Ricardo , Pérez Ramón , Álvarez Marco , Bustamante Pablo , Forray Esteban , Balboa Viviana , Bondi Alexis
Published: July 2024

Not available.
Co-transfection of murine NXPE2 and murine glycophorin A confers reactivity with Ter-119
Authors: Keele Gregory R. , Hay Ariel M. , Holness Nadia K. , Jash Arijita , Ewald Sarah E. , O’Connor Callan , Vincent Matthew , Dzieciatkowska Monika , D’Alessandro Angelo , Churchill Gary A. , Zimring James C.
Published: July 2024

Not available.
Rapid anti-suicidal effect of intravenous ketamine in resistant schizophrenia: a case report
Authors: Ahsan Mohammad Shamsul , Siddique Abul Bashar Md , Kar Ananya , Mubassara Leuza
Published: July 2024

Suicide in schizophrenia is a major risk of premature death. Ketamine has been frequently shown to have immediate antidepressant effect and has a significant role to prevent suicidal attempt and plan in unipolar and bipolar depression. Though use of ketamine in severe depression with psychosis has been proven but the use in psychotic diseases has been generally ignored due to the risk of exacerbating dissociative or psychotic symptoms. We provided a case of a 43-years-old female patient suffering from schizophrenia with significant suicidal ideation and showed that ketamine infusions intravenously at a subanesthetic dose of 0.5mg/kg with a syringe pump infusion had a strong anti-suicidal impact. Importantly, no relevant psychotic or dissociative symptoms occurred during the duration of the augmentation treatment, resulting in prolonged remission of suicidality. This intervention with ketamine was safe and showed significant alleviation of suicidality which might inspire future studies.
Bang J Psychiatry 2023;37(2): 46-48
Examining the behavioral intention toward using smartphone among the university students in Bangladesh
Authors: Ahsan Syed Mohammad Hasib
Published: July 2024

This study endeavors to explore the factors affecting the behavioral intention toward using smartphone by university students in Bangladesh. In this study, “Technology Acceptance Model” (TAM) and “Theory of reasoned action” (TRA) have been integrated to examine the factors that influence attitude as well as an intention toward using smartphone. Factors used in the basic “Technology Acceptance Model” (TAM) include “Perceived Ease of Use” and “Perceived Usefulness”. “Subjective Norm”, deriving from “Theory of Reasoned Action” (TRA), is integrated with the theoretical framework. In this study, a survey is conducted on 428 students of 10 different universities in Bangladesh. Based on a theoretical framework of the study, a questionnaire is adopted from TAM using a seven point Likert’s scale. Statistical techniques such as multicollinearity test, reliability test, construct and discriminant validity, path analysis, and hypothesis testing are used to analyze the primary data. Findings reveal that “Perceived Ease of Use”, “Perceived Usefulness” along with “Subjective Norm” have significant influence on “Attitude toward using smartphone” that directly impact “Behavioral Intention”.
IIUC Business Review, Vol.-11, Issue-1, Dec. 2022, pp. 35-51
Exponential Functions and their Derivatives in the light of Conceptual Image and Conceptual Definition
Authors: Oliveira Saulo Macedo de , Lopes Rieuse
Published: July 2024

This article is an excerpt from a dissertation carried out with students studying Differential and Integral Calculus in the first term of the Information Systems course at the State University of Montes Claros and is based on the theoretical constructs of symbolic interactionism and advanced mathematical thinking, specifically the conceptual image and the conceptual definition of exponential functions. It aimed to understand how and in what way mathematical definitions are used in discussions held in interactions between students and professors during the students’ presentation of a seminar. From the analysis of the data, it was possible to observe divergences between the images and the conceptual definitions of exponential functions and their derivatives. We concluded that the students had made progress in understanding the formal definitions from the advanced mathematical thinking perspective.
A két világháború közötti magyar szépirodalmi utópiák, disztópiák
Authors: Gombos Péter
Published: July 2024

A tanulmány két műfaj, az utópia és a disztópia két világháború közötti megjelenését mutatja be Magyarországon. Mindenekelőtt röviden tisztázom a műfajok egymáshoz való viszonyát, indokolva azt is, miért nem tekinthetők azonosnak. A következő részben a történelmi hátteret mutatom be. Ez már csak azért is indokolt, mert jól látható az összefüggés az ország állapota és az érintett műfajú regényeinek stílusa, eszköztára s általában az alacsony száma között. „A nemzet élő és legnagyobb fájdalma inspirálja ugyan a történettudományokat és a publicisztikát, de nem talál méltó kifejeződésre a szépirodalomban.” – írta Szerb Antal (1991) erről. Írásom fő részében Karinthy Frigyes Capillaria (1921), Kürthy György Mars (1926), Sebes Árpád Doktor Gulliver a sarkvidéken (1930) és Babits Mihály Elza pilóta vagy a tökéletes társadalom (1933) című regényét tárgyalom. Karinthy és Babits művét valamelyest részletesebben elemzem – erre okot ad színességük, kidolgozottságuk és jelentőségük is. A két nagyszerű író remekműve mellett kevésbé tűnnek eredetinek, szellemesnek Kürthy és Sebes történetei. S közben Babits és Karinthy disztópiái is alig hasonlíthatók össze, hiszen az egyikben a humor, az irónia határozza meg az atmoszférát, míg a másikban a reménytelenség.
When are Junctures Critical? The Legacies and Non-Legacies of the Suppression of Local Self-Government
Authors: Gingerich Daniel W. , Vogler Jan P.
Published: July 2024

The suppression of local self-government is a common feature of imperial rule and centralized authoritarianism. Extant scholarship considers such interventions to be potentially legacy-producing. But under which circumstances do these denials of political autonomy lead to sustained changes in political behavior? We develop a novel framework that elucidates when suppression of local self-rule will or will not produce political legacies. Two factors are crucial: the duration of an intervention and the scope of repression. Enduring interventions characterized by encompassing repression are the most likely to generate persistent changes. Contrariwise, transient episodes characterized by limited repressiveness are unlikely to produce legacies. Given our theory's broad character, we conduct empirical analyses in two markedly different settings: Poland, which was split between three major empires, and Brazil, where a military regime installed appointed mayors in certain cities. Our results demonstrate that the suppression of local self-government has varying potential to create legacies.
A novel non-invasive electromagnetic extendable intercalary endoprosthesis: a proof-of-concept study
Authors: Huang Siyi , Yang Jiake , Li Xinyu , Tang Xiaodong , Ji Tao
Published: July 2024

Introduction: Femur and tibia are the most commonly affected sites for primary malignant bone tumors in children. The wide resection of the tumor frequently requires the physis to be resected. The normal growth of the unaffected limb will result in a significant limb length discrepancy at skeletal maturity. To compensate for this resulting LLD, different generations of extendible endoprostheses have been developed. Non-invasive extendable prostheses eliminate the need for surgical procedures and general anesthesia, enabling gradual and painless lengthening. Currently available non-invasive extendable prostheses focus on joint reconstruction, and no case series analysis of intercalary non-invasive extendable prosthesis has been reported. Therefore, we have designed a novel non-invasive electromagnetic extendable intercalary endoprosthesis.

Methods:In vitro mechanical experiments and in vivo animal experiments were conducted.

Results:In vitro experiments have confirmed that the prosthetics can extend at a constant rate, increasing by 4.4 mm every 10 min. The average maximum extension force during prosthetic elongation can reach 1306N. In animal in vivo experiments, the extension process is smooth and non-invasive, and the sheep is in a comfortable state.

Discussion: The in vitro and in vivo animal studies provide evidence to support the extension reliability, laying the foundation for future large-scale validation experiments.
Microbiome-host interactions in the pathogenesis of acute exacerbation of chronic obstructive pulmonary disease
Authors: Li Yao , Mao Xiaoyan , Shi Pengfei , Wan Zongren , Yang Dan , Ma Ting , Wang Baolan , Wang Jipeng , Wang Jingjing , Zhu Rong
Published: July 2024

Objective

To explore the underlying mechanisms the airway microbiome contributes to Acute Exacerbation of Chronic Obstructive Pulmonary Disease(AECOPD).

Methods

We enrolled 31 AECOPD patients and 26 stable COPD patients, their sputum samples were collected for metagenomic and RNA sequencing, and then subjected to bioinformatic analyses. The expression of host genes was validated by Quantitative Real-time PCR(qPCR) using the same batch of specimens.

Results

Our results indicated a higher expression of Rothia mucilaginosa(p=0.015) in the AECOPD group and Haemophilus influenzae(p=0.005) in the COPD group. The Different expressed genes(DEGs) detected were significantly enriched in "type I interferon signaling pathway"(p<0.001, q=0.001) in gene function annotation, and "Cytosolic DNA-sensing pathway"(p=0.002, q=0.024), "Toll-like receptor signaling pathway"(p=0.006, q=0.045), and "TNF signaling pathway"(p=0.006, q=0.045) in KEGG enrichment analysis. qPCR amplification experiment verified that the expression of OASL and IL6 increased significantly in the AECOPD group.

Conclusion

Pulmonary bacteria dysbiosis may regulate the pathogenesis of AECOPD through innate immune system pathways like type I interferon signaling pathway and Toll-like receptor signaling pathway.
A matter of annotation: an empirical study on in situ and self-recall activity annotations from wearable sensors
Authors: Hoelzemann Alexander , Van Laerhoven Kristof
Published: July 2024

Research into the detection of human activities from wearable sensors is a highly active field, benefiting numerous applications, from ambulatory monitoring of healthcare patients via fitness coaching to streamlining manual work processes. We present an empirical study that evaluates and contrasts four commonly employed annotation methods in user studies focused on in-the-wild data collection. For both the user-driven,in situannotations, where participants annotate their activities during the actual recording process, and the recall methods, where participants retrospectively annotate their data at the end of each day, the participants had the flexibility to select their own set of activity classes and corresponding labels. Our study illustrates that different labeling methodologies directly impact the annotations' quality, as well as the capabilities of a deep learning classifier trained with the data. We noticed thatin situmethods produce less but more precise labels than recall methods. Furthermore, we combined an activity diary with a visualization tool that enables the participant to inspect and label their activity data. Due to the introduction of such a tool were able to decrease missing annotations and increase the annotation consistency, and therefore the F1-Score of the deep learning model by up to 8% (ranging between 82.1 and 90.4% F1-Score). Furthermore, we discuss the advantages and disadvantages of the methods compared in our study, the biases they could introduce, and the consequences of their usage on human activity recognition studies as well as possible solutions.
How do students deal with the uncertainty of sustainability challenges? Metacognitive learning in a transdisciplinary course
Authors: Bohm Nina L. , Klaassen Renate G. , van Bueren Ellen , den Brok Perry
Published: July 2024

While tackling sustainability challenges, engineering students confront various uncertainties, including the unpredictability of real-world scenarios, unfamiliar aspects of problems, and conflicting viewpoints among stakeholders. Despite previous research indicating the likelihood of encountering such uncertainties in sustainability projects, it is unclear if students are aware of uncertainty and what specific regulatory behaviors they develop to address them. This study seeks to deepen our understanding of the awareness and regulation of uncertainty by students while they work on real-life sustainability challenges. To achieve this, we observed nine MSc students enrolled in a transdisciplinary course on urban sustainability at a Dutch university of technology. Through interviews, we explored the uncertainties they faced and how they navigated them. Our analysis, conducted through open, consensus-based coding by two researchers, revealed that students primarily encountered the uncertainty of multiplicity, characterized by divergent stakeholder perspectives. Additionally, students increasingly recognized the inherent unpredictability of the challenges over the course. To address uncertainty, students developed three kinds of behaviors to deal with uncertainty: seeking social support from commissioners, coaches, and peers; employing small coping mechanisms to overcome obstacles; and developing attitudes such as empathy, flexibility, and relativism. This study offers detailed insights into how students navigate uncertainty. Moving forward, efforts in uncertainty education should prioritize how educators can positively influence the development of metacognition in uncertainty.
Examining the relationship between attitudes toward science and socioeconomic status among middle-class, midwestern middle school students
Authors: Porter-Stransky Kirsten A. , Yang Wenxin , Vollbrecht Peter J.
Published: July 2024

Background

Previous research has uncovered disparities in children’s attitudes toward science based on gender, income, parenting, geographical location, and school resources, among other factors. However, less is known about socioeconomic influences on science attitudes within the evolving rural middle class. The present study investigated the relationship between indicators of socioeconomic status on middle schoolers’ attitudes toward science in a predominantly middle class, white, rural sample within the midwestern United States of America.

Methods

Parents were asked for demographic information and consent for their child participating in the study. Middle school children were invited to complete a short survey quantifying their attitudes toward science.

Results

Science attitudes did not vary based on gender. However, students with at least one parent that earned at least a bachelor’s degree or from a household income exceeding $90,000 had more positive attitudes toward science than those whose parents did not obtain a college degree or whose household income was less than $90,000, respectively. Regression revealed that household income and parent’s assessment of their child’s interest in a scientific career significantly predicted a child’s attitudes toward science, but gender and highest degree earned by a parent did not.

Conclusion

This study found differences in children’s science attitudes within a rural, predominantly middle-class population. This finding contributes to the literature by revealing differences in science attitudes relating to higher levels of parental education (bachelor’s degree) and income ($90,000) than previously identified. This highlights additional opportunities to support children’s science growth and promote equitable science opportunities for everyone.
Perinatal complications and neonatal outcomes in in vitro fertilization/intracytoplasmic sperm injection: a propensity score matching cohort study
Authors: Chen Ying , Zhang Mengjie , Gao Yumei , Li Mingming , Zheng Wenjun , Guo Xueyan , Li Fei
Published: July 2024

Background

The utilization of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) has witnessed a significant increase in recent years. However, the comparative perinatal and neonatal outcomes compared to natural pregnancies are unclear. This study aims to compare the outcomes of pregnancies from IVF and ICSI with natural pregnancies.

Methods

This retrospective, propensity score-matched cohort study was conducted at the First People’s Hospital of Shangqiu and The First Affiliated Hospital of Xinjiang Medical University, involving 5,628 patients from February 2019 to December 2022. It compared pregnancies achieved through IVF/ICSI with those conceived naturally. The primary outcomes assessed were perinatal complications and neonatal health parameters. Propensity score matching and multivariate logistic regression analysis were employed to adjust for potential confounders and identify independent associations.

Results

After propensity score matching, the IVF/ICSI group demonstrated significantly higher rates of placental adherence (12.1% vs. 7.4%, p < 0.001) and postpartum hemorrhage (11.1% vs. 7.6%, p = 0.002) compared to the NP group. Neonates in the IVF/ICSI group had a lower gestational age (38.21 ± 2.12 weeks vs. 38.63 ± 2.29 weeks, p < 0.001), reduced birth weight (3159.42 ± 722.75 g vs. 3211.31 ± 624.42 g, p = 0.032), and an increased preterm delivery rate (11.2% vs. 8.9%, p = 0.017). Multivariate analysis further confirmed these findings, highlighting the independent associations between IVF/ICSI and these adverse outcomes.

Conclusion

This study suggests a potential correlation between the use of IVF/ICSI and unfavorable perinatal and neonatal outcomes. These findings underscore the critical need for ongoing monitoring and research efforts to enhance the safety and effectiveness of these reproductive technologies.
Evidence of innate training in bovine γδ T cells following subcutaneous BCG administration
Authors: Samuel Beulah Esther Rani , Diaz Fabian E. , Maina Teresia W. , Corbett Ryan J. , Tuggle Christopher K. , McGill Jodi L.
Published: July 2024

The Bacillus Calmette Guerin (BCG) vaccine has been shown to induce non-specific protection against diseases other than tuberculosis in vaccinated individuals, attributed to the induction of trained immunity. We have previously demonstrated that BCG administration induces innate immune training in mixed peripheral blood mononuclear cells and monocytes in calves. Gamma Delta (γδ) T cells are non-conventional T cells that exhibit innate and adaptive immune system features. They are in higher proportion in the peripheral blood of cattle than humans or rodents and play an essential role in bovine immune response to pathogens. In the current study, we determined if BCG administration induced innate immune training in bovine γδ T cells. A group of 16 pre-weaned Holstein calves (2-4 d age) were enrolled in the study and randomly assigned to vaccine and control groups (n=8/group). The vaccine group received two doses of 106 colony forming units (CFU) BCG Danish strain subcutaneously, separated by 2 weeks. The control group remained unvaccinated. Gamma delta T cells were purified from peripheral blood using magnetic cell sorting three weeks after receiving the 1st BCG dose. We observed functional changes in the γδ T cells from BCG-treated calves shown by increased IL-6 and TNF-α cytokine production in response to in vitro stimulation with Escherichia coli LPS and PAM3CSK4. ATAC-Seq analysis of 78,278 regions of open chromatin (peaks) revealed that γδ T cells from BCG-treated calves had an altered epigenetic status compared to cells from the control calves. Differentially accessible peaks (DAP) found near the promoters of innate immunity-related genes like Siglec14, Irf4, Ifna2, Lrrfip1, and Tnfrsf10d were 1 to 4-fold more accessible in cells from BCG-treated calves. MOTIF enrichment analysis of the sequences within DAPs, which explores transcription factor binding motifs (TFBM) upstream of regulatory elements, revealed TFBM for Eomes and IRF-5 were among the most enriched transcription factors. GO enrichment analysis of genes proximal to the DAPs showed enrichment of pathways such as regulation of IL-2 production, T-cell receptor signaling pathway, and other immune regulatory pathways. In conclusion, our study shows that subcutaneous BCG administration in pre-weaned calves can induce innate immune memory in the form of trained immunity in γδ T cells. This memory is associated with increased chromatin accessibility of innate immune response-related genes, thereby inducing a functional trained immune response evidenced by increased IL-6 and TNF-α cytokine production.