bluuebunny/crossref_metadata_2025 huggingface dataset:
Interactions of Genes and Sodium Intake on the Development of Hypertension: A Cohort-Based Case-Control Study
Authors: Chen Mei-Ling , Huang Tzu-Pi , Chen Tai-Wei , Chan Hsin-Hua , Hwang Bing-Fang
Published: May 2018

There have been few studies investigating interactions of G-protein beta3 subunit (GNB3) C825T (rs5443) and dietary sodium intake on the risk of hypertension, i.e., BP salt sensitivity. The study aims to evaluate joint effects of GNB3 polymorphisms and sodium consumption on the development of hypertension. A cohort-based case-control study was conducted in 2014. There are 233 participants with newly diagnosed hypertension in the case group and 699 participants in the gender-matched control group. The primary outcome is the development of hypertension over a 10-year period. The determinants of hypertension were three genotypes of SNP in GNB3 (TT; CT; and CC) and two dietary salt categories on the basis of the level of sodium consumption representing high (>4800 mg/day) and low-sodium (<2400 mg/day) diets. The development of hypertension increased with participants carrying TT genotype and high-sodium diets comparing with those carrying TC or CC genotype with low-sodium diets (adjusted OR 3.23, 95% CI 1.52–6.83) (Rothman synergy index = 3.79). The study suggests that GNB3 C825T polymorphism may influence the response of the renin-angiotensin system to high-sodium diet. It implies that GNB3 can be served as an easy, inexpensive, and early genetic marker of salt sensitivity to blood pressure. Salt-sensitive individuals should pay more attention to salt intake to reduce cardiovascular morbidity or mortality.
A Simple Line Clustering Method for Spatial Analysis with Origin-Destination Data and Its Application to Bike-Sharing Movement Data
Authors: He Biao , Zhang Yan , Chen Yu , Gu Zhihui
Published: May 2018

Clustering methods are popular tools for pattern recognition in spatial databases. Existing clustering methods have mainly focused on the matching and clustering of complex trajectories. Few studies have paid attention to clustering origin-destination (OD) trips and discovering strong spatial linkages via OD lines, which is useful in many areas such as transportation, urban planning, and migration studies. In this paper, we present a new Simple Line Clustering Method (SLCM) that was designed to discover the strongest spatial linkage by searching for neighboring lines for every OD trip within a certain radius. This method adopts entropy theory and the probability distribution function for parameter selection to ensure significant clustering results. We demonstrate this method using bike-sharing location data in a metropolitan city. Results show that (1) the SLCM was significantly effective in discovering clusters at different scales, (2) results with the SLCM analysis confirmed known structures and discovered unknown structures, and (3) this approach can also be applied to other OD data to facilitate pattern extraction and structure understanding.
UDP-Glucose 4-Epimerase and β-1,4-Galactosyltransferase from the Oyster Magallana gigas as Valuable Biocatalysts for the Production of Galactosylated Products
Authors: Song Hui-Bo , He Meng , Cai Zhi-Peng , Huang Kun , Flitsch Sabine L. , Liu Li , Voglmeir Josef
Published: May 2018

Uridine diphosphate galactose (UDP-galactose) is a valuable building block in the enzymatic synthesis of galactose-containing glycoconjugates. UDP-glucose 4-epimerase (UGE) is an enzyme which catalyzes the reversible conversion of abundantly available UDP-glucose to UDP-galactose. Herein, we described the cloning, expression, purification, and biochemical characterization of an unstudied UGE from the oyster Magallana gigas (MgUGE). Activity tests of recombinantly expressed MgUGE, using HPLC (high-performance liquid chromatography), mass spectrometry, and photometric assays, showed an optimal temperature of 16 °C, and reasonable thermal stability up to 37 °C. No metal ions were required for enzymatic activity. The simple nickel-affinity-purification procedure makes MgUGE a valuable biocatalyst for the synthesis of UDP-galactose from UDP-glucose. The biosynthetic potential of MgUGE was further exemplified in a coupled enzymatic reaction with an oyster-derived β-1,4-galactosyltransferase (MgGalT7), allowing the galactosylation of the model substrate para-nitrophenol xylose (pNP-xylose) using UDP-glucose as the starting material.
In Vitro Antifungal Activity of New and Known Geranylated Phenols against Phytophthora cinnamomi Rands
Authors: Chavez María I. , Soto Mauricio , Cimino Franco A. , Olea Andrés F. , Espinoza Luis , Díaz Katy , Taborga Lautaro
Published: May 2018

A series of new and known geranylated phenol/methoxyphenol derivatives has been tested in vitro as inhibitor agents of mycelial growth of Phytophthora cinnamomi. The activity of tested compounds is correlated with the nature, number, and position of the substituent group on the aromatic ring. Results indicate that the most active geranylated derivatives are those having two hydroxyl groups (or one –OH and one –OCH3) attached to the aromatic ring. Interestingly, these derivatives are as active as Metalaxil®, a commonly used commercial fungicide. Thus, our results suggest that some of these compounds might be of agricultural interest due to their potential use as fungicides against P. cinnamomi. The effect of structure on fungicide activity is discussed in terms of electronic distribution on both the aromatic ring and side geranyl chain. All tested compounds have been synthesized by direct coupling of geraniol and the respective phenol. Interestingly, new digeranylated derivatives were obtained by increasing the reaction time.
Quinolones Modulate Ghrelin Receptor Signaling: Potential for a Novel Small Molecule Scaffold in the Treatment of Cachexia
Authors: Torres-Fuentes Cristina , Pastor-Cavada Elena , Cano Rafael , Kandil Dalia , Shanahan Rachel , Juan Rocio , Shaban Hamdy , McGlacken Gerard , Schellekens Harriët
Published: May 2018

Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive pulmonary disease, and kidney disease and significantly impedes treatment outcome and therapy tolerance, reducing physical function and increasing mortality. Current cachexia treatments are limited and new pharmacological strategies are needed. Agonists for the growth hormone secretagogue (GHS-R1a), or ghrelin receptor, prospectively regulate the central regulation of appetite and growth hormone secretion, and therefore have tremendous potential as cachexia therapeutics. Non-peptide GHS-R1a agonists are of particular interest, especially given the high gastrointestinal degradation of peptide-based structures, including that of the endogenous ligand, ghrelin, which has a half-life of only 30 min. However, few compounds have been reported in the literature as non-peptide GHS-R1a agonists. In this paper, we investigate the in vitro potential of quinolone compounds to modulate the GHS-R1a in both transfected human cells and mouse hypothalamic cells. These chemically synthesized compounds demonstrate a promising potential as GHS-R1a agonists, shown by an increased intracellular calcium influx. Further studies are now warranted to substantiate and exploit the potential of these novel quinolone-based compounds as orexigenic therapeutics in conditions of cachexia and other metabolic and eating disorders.
The Role of Endoplasmic Reticulum Stress-Glycogen Synthase Kinase-3 Signaling in Atherogenesis
Authors: Huang Aric , Patel Sarvatit , McAlpine Cameron S. , Werstuck Geoff H.
Published: May 2018

Cardiovascular disease (CVD) is the number one cause of global mortality and atherosclerosis is the underlying cause of most CVD. However, the molecular mechanisms by which cardiovascular risk factors promote the development of atherosclerosis are not well understood. The development of new efficient therapies to directly block or slow disease progression will require a better understanding of these mechanisms. Accumulating evidence supports a role for endoplasmic reticulum (ER) stress in all stages of the developing atherosclerotic lesion however, it was not clear how ER stress may contribute to disease progression. Recent findings have shown that ER stress signaling through glycogen synthase kinase (GSK)-3α may significantly contribute to macrophage lipid accumulation, inflammatory cytokine production and M1macrophage polarization. In this review we summarize our knowledge of the potential role of ER stress-GSK3 signaling in the development and progression of atherosclerosis as well as the possible therapeutic implications of this pathway.
Molecular Engineering of High Energy Barrier in Single-Molecule Magnets Based on [MoIII(CN)7]4− and V(II) Complexes
Authors: Mironov Vladimir S.
Published: May 2018

Molecular engineering of high energy barrier Ueff in single-molecule magnets (SMMs) of general composition MoIIIkVIIm based on orbitally-degenerate pentagonal-bipyramidal [MoIII(CN)7]4− complexes with unquenched orbital momentum and high-spin V(II) complexes is discussed. In these SMMs, the barrier originates exclusively from anisotropic Ising-type exchange interactions −Jxy(SixSjx + SiySjy) − JzSizSjz in the apical cyano-bridged pairs MoIII–CN–VII, which produce a double-well energy profile with a doubly degenerate ground spin state ±MS. It is shown that the spin-reversal barrier Ueff is controlled by anisotropic exchange parameters Jz, Jxy, and the number n of apical MoIII–CN–VII groups in a SMM cluster, Ueff ~ 0.5|Jz − Jxy|n; it can reach a value of many hundreds of wavenumbers (up to 741 cm−1). This finding provides a very efficient straightforward strategy for further scaling Ueff to high values (>1000 cm−1) by means of enhancing exchange parameters Jz, Jxy, and increasing the number of [MoIII(CN)7]4− complexes in a SMM molecule.
Vibration Technologies for Friction Reduction to Overcome Weight Transfer Challenge in Horizontal Wells Using a Multiscale Friction Model
Authors: Wang Xing-Ming , Yao Xing-Miao
Published: May 2018

Drag reduction technologies mainly include the mechanical method and the chemical method. Mechanical drag reduction technologies are widespread in the drilling field due to their environmental friendliness and ease of use. Vibration technologies are among some of the most-used mechanical drag reduction technologies. However, various types of vibration tools have the negative effect of obstructing the promotion and application of mechanical drag reduction technologies. This paper widely investigated the types and applications of vibration tools. A drilling agitator system and slider drilling technology were included. The structure and mechanism of the vibration tool were studied. A multiscale friction model was proposed based on the Dahl model according to the drilling environment. The model was verified using experimental data. The multiscale friction model was used to analyze the drag reduction mechanism and the effect of different kinds of vibration technologies. Simulations demonstrated that vibration technologies can effectively reduce the axial friction of the drill string. Longitudinal vibration can reduce the axial friction such that the dependence of the reduced coefficient of friction on the reduced velocity does not change significantly after the reduced oscillation amplitude exceeds the critical value of one. Axial friction decreased with the increasing amplitude of the radial vibration. However, the reduction effect has no relationship with the rate of penetration (ROP). Torsional vibration and rocking motion can reduce the axial friction force. When the oscillation amplitude increases, the axial friction decreases. The reduction effect of slider drilling technology is better than torsional vibration and two other technologies in terms of friction reduction.
A Friction-Inertial-Based Rotary Motor: Design, Modelling and Experiments
Authors: Zhang Bo , Chen Fangxin , Li Haiyang , Du Zhijiang , Sun Lining , Dong Wei
Published: May 2018

A friction–inertial-based rotary motor driven by shear piezoelectric actuators (SPAs) is proposed in this paper, which possesses many superior features, including high resolution, compact size, large load-capacity, and low cost. In order to eliminate the step loss and increase the step size when an external load is applied, the power-function-shape driving signal was used to actuate the rotary motor. According to the step characteristics under this driving signal, two motion modes were observed and defined, namely the stick-shoot motion mode and the stick-slip-shoot motion mode. The former motion mode can realize a large step size while the later one cannot due to the slipping during the rising phase. After analyzing the results from the numerical simulation and the experiment study, it was found that the motion performance of the motor is closely related to the preload and the base number of the driving signal rather than the size of SPAs, which means the motor can be further downsized according to its actual requirements.
Evaluation of Fine Aggregate Morphology by Image Method and Its Effect on Skid-Resistance of Micro-Surfacing
Authors: Xiao Yue , Wang Feng , Cui Peide , Lei Lei , Lin Juntao , Yi Mingwei
Published: May 2018

Micro-surfacing is a widely used pavement preventive maintenance technology used all over the world, due to its advantages of fast construction, low maintenance cost, good waterproofness, and skid-resistance performance. This study evaluated the fine aggregate morphology and surface texture of micro-surfacing by AIMS (aggregate image measurement system), and explored the effect of aggregate morphology on skid-resistance of single-grade micro-surfacing. Sand patch test and British pendulum test were also used to detect skid-resistance for comparison with the image-based method. Wet abrasion test was used to measure skid-resistance durability for feasibility verification of single-grade micro-surfacing. The results show that the effect of Form2D on the skid-resistance of micro-surfacing is much stronger than that of angularity. Combining the feasibility analysis of durability and skid-resistance, 1.18–2.36 grade micro-surfacing meets the requirements of durability and skid-resistance at the same time. This study also determined that, compared with British pendulum test, the texture result obtained by sand patch test fits better with results of image method.
Mechanical and Morphological Effect of Plant Based Antimicrobial Solutions on Maxillofacial Silicone Elastomer
Authors: Tetteh Sophia , Bibb Richard J. , Martin Simon J.
Published: May 2018

The objective of this study was to determine the effect of plant based antimicrobial solutions specifically tea tree and Manuka oil on facial silicone elastomers. The purpose of this in vitro study was to evaluate the effect of disinfection with plant extract solution on mechanical properties and morphology on the silicone elastomer. Test specimens were subjected to disinfection using tea tree oil, Manuka oil and the staphylococcus epidermidis bacteria. Furthermore, a procedure duration was used in the disinfection process to simulate up to one year of usage. Over 500 test specimens were fabricated for all tests performed namely hardness, elongation, tensile, tear strength tests, visual inspection and lastly surface characterization using SEM. A repeated measures ANOVA revealed that hardness and elongation at break varied significantly over the time period, whereas this was not observed in the tear and tensile strength parameters of the test samples.
Timing of Secondary Hydrothermal Alteration of the Luobusa Chromitites Constrained by Ar/Ar Dating of Chrome Chlorites
Authors: Guo Wei , He Huaiyu , Li Youjuan , Bai Xiujuan , Su Fei , Liu Yan , Zhu Rixiang
Published: May 2018

Chrome chlorites are usually found as secondary phases formed by hydrothermal alteration of chromite deposits and associated mafic/ultramafic rocks. Here, we report the 40Ar/39Ar age of chrome chlorites separated from the Luobusa massive chromitites which have undergone secondary alteration by CO2-rich hydrothermal fluids. The dating results reveal that the intermediate heating steps (from 4 to 10) of sample L7 generate an age plateau of 29.88 ± 0.42 Ma (MSWD = 0.12, plateau 39Ar = 74.6%), and the plateau data points define a concordant inverse isochron age of 30.15 ± 1.05 Ma (MSWD = 0.08, initial 40Ar/36Ar = 295.8 ± 9.7). The Ar release pattern shows no evidence of later degassing or inherited radiogenic component indicated by an atmospheric intercept, thus representing the age of the hydrothermal activity. Based on the agreement of this hydrothermal age with the ~30 Ma adakitic plutons exposed in nearby regions (the Zedong area, tens of kilometers west Luobusa) and the extensive late Oligocene plutonism distributed along the southeastern Gangdese magmatic belt, it is suggested that the hydrothermal fluids are likely related to the ~30 Ma magmatism. The hydrothermal fluid circulation could be launched either by remote plutons (such as the Sangri granodiorite, the nearest ~30 Ma pluton west Luobusa) or by a similar coeval pluton in the local Luobusa area (inferred, not found or reported so far). Our results provide important clues for when the listwanites in Luobusa were formed.
Microcrack Evolution and Associated Deformation and Strength Properties of Sandstone Samples Subjected to Various Strain Rates
Authors: Chen Chong-Feng , Xu Tao , Li Shao-Hua
Published: May 2018

The evolution of micro-cracks in rocks under different strain rates is of great importance for a better understanding of the mechanical properties of rocks under complex stress states. In the present study, a series of tests were carried out under various strain rates, ranging from creep tests to intermediate strain rate tests, so as to observe the evolution of micro-cracks in rock and to investigate the influence of the strain rate on the deformation and strength properties of rocks. Thin sections from rock samples at pre- and post-failure were compared and analyzed at the microscale using an optical microscope. The results demonstrate that the main crack propagation in the rock is intergranular at a creep strain rate and transgranular at a higher strain rate. However, intergranular cracks appear mainly around the quartz and most of the punctured grains are quartz. Furthermore, the intergranular and transgranular cracks exhibit large differences in the different loading directions. In addition, uniaxial compressive tests were conducted on the unbroken rock samples in the creep tests. A comparison of the stress–strain curves of the creep tests and the intermediate strain rate tests indicate that Young’s modulus and the peak strength increase with the strain rate. In addition, more deformation energy is released by the generation of the transgranular cracks than the generation of the intergranular cracks. This study illustrates that the conspicuous crack evolution under different strain rates helps to understand the crack development on a microscale, and explains the relationship between the micro- and macro-behaviors of rock before the collapse under different strain rates.
Geophysical Investigation of the Pb–Zn Deposit of Lontzen–Poppelsberg, Belgium
Authors: Evrard Maxime , Dumont Gaël , Hermans Thomas , Chouteau Michel , Francis Olivier , Pirard Eric , Nguyen Frédéric
Published: May 2018

The drillhole information from the Lontzen–Poppelsberg site has demonstrated three orebodies and has allowed the estimation of the extension of the lodes, their dip, and the location at the ground surface. The localisation of the lodes makes them excellent targets for further exploration with geophysics. This deposit is classified as a Mississippi Valley Type (MVT) deposit. It consists mainly of Pb–Zn–Fe sulphides that display contrasting values in resistivity, chargeability, density, and magnetic susceptibility, with regards to the sedimentary host rocks. The dipole–dipole direct current (DC) resistivity and induce polarization (IP) profiles have been collected and inverted to successfully delineate the Pb–Zn mineralization and the geological structures. Short-spacing EM34 electromagnetic conductivity data were collected mainly on the top of Poppelsberg East lode and have revealed a conductive body matching with the geologically modelled mineralization. Gravity profiles have been carried out perpendicularly to the lode orientation; they show a strong structural anomaly. High resolution ground magnetic data were collected over the study area, but they showed no anomaly over the ore deposits. The geophysical inversion results are complementary to the model based on drill information, and allow us to refine the delineation of the mineralization. The identification of the geophysical signatures of this deposit permits targeting new possible mineralization in the area.
Review of Fabrication Methods, Physical Properties, and Applications of Nanostructured Copper Oxides Formed via Electrochemical Oxidation
Authors: Stepniowski Wojciech J. , Misiolek Wojciech Z.
Published: May 2018

Typically, anodic oxidation of metals results in the formation of hexagonally arranged nanoporous or nanotubular oxide, with a specific oxidation state of the transition metal. Recently, the majority of transition metals have been anodized; however, the formation of copper oxides by electrochemical oxidation is yet unexplored and offers numerous, unique properties and applications. Nanowires formed by copper electrochemical oxidation are crystalline and composed of cuprous (CuO) or cupric oxide (Cu2O), bringing varied physical and chemical properties to the nanostructured morphology and different band gaps: 1.44 and 2.22 eV, respectively. According to its Pourbaix (potential-pH) diagram, the passivity of copper occurs at ambient and alkaline pH. In order to grow oxide nanostructures on copper, alkaline electrolytes like NaOH and KOH are used. To date, no systemic study has yet been reported on the influence of the operating conditions, such as the type of electrolyte, its temperature, and applied potential, on the morphology of the grown nanostructures. However, the numerous reports gathered in this paper will provide a certain view on the matter. After passivation, the formed nanostructures can be also post-treated. Post-treatments employ calcinations or chemical reactions, including the chemical reduction of the grown oxides. Nanostructures made of CuO or Cu2O have a broad range of potential applications. On one hand, with the use of surface morphology, the wetting contact angle is tuned. On the other hand, the chemical composition (pure Cu2O) and high surface area make such materials attractive for renewable energy harvesting, including water splitting. While compared to other fabrication techniques, self-organized anodization is a facile, easy to scale-up, time-efficient approach, providing high-aspect ratio one-dimensional (1D) nanostructures. Despite these advantages, there are still numerous challenges that have to be faced, including the strict control of the chemical composition and morphology of the grown nanostructures, their uniformity, and understanding the mechanism of their growth.
Milk Fermented by Specific Lactobacillus Strains Regulates the Serum Levels of IL-6, TNF-α and IL-10 Cytokines in a LPS-Stimulated Murine Model
Authors: Reyes-Díaz Aline , Mata-Haro Verónica , Hernández Jesús , González-Córdova Aarón F. , Hernández-Mendoza Adrián , Reyes-Díaz Ricardo , Torres-Llanez María J. , Beltrán-Barrientos Lilia M. , Vallejo-Cordoba Belinda
Published: May 2018

Studies report that metabolites, such as peptides, present in fermented milk with specific lactic acid bacteria, may regulate cytokine production and exert an anti-inflammatory effect. Hence, the cytokine regulatory effect of fermented milk by specific Lactobacillus strains was evaluated in a lipopolysaccharide (LPS)-stimulated murine model. From twelve strains, three (J20, J23 and J28) were selected for their high proteolytic and acidifying capacities in milk and used for the in vivo study. Three treatments (fermented milk, FM; pasteurized fermented milk, PFM; and its <10 kDa fractions, PFM10) were administrated daily for four weeks. After treatments, animals were induced to a systemic inflammation with LPS, and blood samples were collected 6 h post-LPS injection for cytokine analyses. Results showed that FM or PFM significantly (p > 0.05) reduced pro-inflammatory cytokine (IL-6 and TNF-α) concentrations and significantly increased anti-inflammatory (IL-10) cytokine concentrations in comparison to the control; also, pro-inflammatory cytokines were reduced for animals treated with PFM10 (p < 0.05). RP-HPLC-MS/MS analysis showed that water-soluble extracts (<10 kDa) from PFM with J28 presented 15 new peptides, which may be the metabolites involved in the cytokine regulatory effect of fermented milk.
Biological and Psychosocial Processes in the Development of Children’s Appetitive Traits: Insights from Developmental Theory and Research
Authors: Russell Catherine G. , Russell Alan
Published: May 2018

There has been increasing concern expressed about children’s food intakes and dietary patterns. These are closely linked to children’s appetitive traits (such as disinhibited eating and food fussiness/neophobia). Research has examined both biological and psychosocial correlates or predictors of these traits. There has been less focus on possible processes or mechanisms associated with children’s development of these traits and research that links biological and psychosocial factors. There is an absence of research that links biological and psychosocial factors. In the present article, we outline a model intended to facilitate theory and research on the development of appetitive traits. It is based on scholarship from developmental theory and research and incorporates biological factors such as genetic predispositions and temperament as well as psychosocial factors in terms of parent cognitions, feeding styles and feeding practices. Particular attention is directed to aspects such as emotional eating and feeding, self-regulation of energy intake, and non-shared family environments. We highlight the opportunity for longitudinal research that examines bidirectional, transactional and cascade processes and uses a developmental framework. The model provides a basis for connecting the biological foundations of appetitive traits to system-level analysis in the family. Knowledge generated through the application of the model should lead to more effective prevention and intervention initiatives.
Postprandial Glycaemic Responses of Dried Fruit-Containing Meals in Healthy Adults: Results from a Randomised Trial
Authors: Zhu Ruixin , Fan Zhihong , Dong Yang , Liu Manman , Wang Linlin , Pan Haikun
Published: May 2018

The aim of this study was to explore the glycaemic response (GR) patterns of four dried fruits (DF) and the mixed meals containing dried fruits, rice and almonds. Dried apples (DApp), dried jujubes (DJ), raisins (Ra) and dried apricots (DApr) were tested in eleven healthy subjects in random order. Test meals included the following 3 groups: (1) dried fruits containing 50 g available carbohydrates; (2) mixed meals consisting of DF and rice (DF + R), each contributing 25 g available carbohydrates; (3) Group (2) supplemented with 30 g almonds (DF + R + A). The postprandial GR and other characteristics in 240 min were investigated. The GI values of 4 DFs were 43 for DApp, 55 for DJ, 56 for both Ra and DApr. The DApp displayed the smallest amplitude of glycaemic excursion within 240 min (MAGE0–240). Compared with rice, the DApp + R meal elicited a significantly reduced GR and a smaller MAGE0–240 (GI 81 vs. 65). With the addition of almonds, the GIs and MAGE0–240 decreased significantly in all DF + A + R combinations except DApp + R + A. The ratio of total fructose/glucose contents of test meals were negatively correlated to GIs. Dried fruits and nuts may have the potential to mitigate the postprandial GR when jointly introduced into glycaemic management diets.
Modeling Photosynthetically Active Radiation from Satellite-Derived Estimations over Mainland Spain
Authors: Vindel Jose , Valenzuela Rita , Navarro Ana , Zarzalejo Luis , Paz-Gallardo Abel , Souto José , Méndez-Gómez Ramón , Cartelle David , Casares Juan
Published: May 2018

A model based on the known high correlation between photosynthetically active radiation (PAR) and global horizontal irradiance (GHI) was implemented to estimate PAR from GHI measurements in this present study. The model has been developed using satellite-derived GHI and PAR estimations. Both variables can be estimated using Kato bands, provided by Satellite Application Facility on Climate Monitoring (CM-SAF), and its ratio may be used as the variable of interest in order to obtain the model. The study area, which was located in mainland Spain, has been split by cluster analysis into regions with similar behavior, according to this ratio. In each of these regions, a regression model estimating PAR from GHI has been developed. According to the analysis, two regions are distinguished in the study area. These regions belong to the two climates dominating the territory: an Oceanic climate on the northern edge; and a Mediterranean climate with hot summer in the rest of the study area. The models obtained for each region have been checked against the ground measurements, providing correlograms with determination coefficients higher than 0.99.
Supervoxels-Based Histon as a New Alzheimer’s Disease Imaging Biomarker
Authors: Toro César , Gonzalo-Martín Consuelo , García-Pedrero Angel , Menasalvas Ruiz Ernestina
Published: May 2018

Alzheimer’s disease (AD) represents the prevalent type of dementia in the elderly, and is characterized by the presence of neurofibrillary tangles and amyloid plaques that eventually leads to the loss of neurons, resulting in atrophy in specific brain areas. Although the process of degeneration can be visualized through various modalities of medical imaging and has proved to be a valuable biomarker, the accurate diagnosis of Alzheimer’s disease remains a challenge, especially in its early stages. In this paper, we propose a novel classification method for Alzheimer’s disease/cognitive normal discrimination in structural magnetic resonance images (MRI), based on the extension of the concept of histons to volumetric images. The proposed method exploits the relationship between grey matter, white matter and cerebrospinal fluid degeneration by means of a segmentation using supervoxels. The calculated histons are then processed for a reduction in dimensionality using principal components analysis (PCA) and the resulting vector is used to train an support vector machine (SVM) classifier. Experimental results using the OASIS-1 database have proven to be a significant improvement compared to a baseline classification made using the pipeline provided by Clinica software.
Accurate Fall Detection in a Top View Privacy Preserving Configuration
Authors: Ricciuti Manola , Spinsante Susanna , Gambi Ennio
Published: May 2018

Fall detection is one of the most investigated themes in the research on assistive solutions for aged people. In particular, a false-alarm-free discrimination between falls and non-falls is indispensable, especially to assist elderly people living alone. Current technological solutions designed to monitor several types of activities in indoor environments can guarantee absolute privacy to the people that decide to rely on them. Devices integrating RGB and depth cameras, such as the Microsoft Kinect, can ensure privacy and anonymity, since the depth information is considered to extract only meaningful information from video streams. In this paper, we propose an accurate fall detection method investigating the depth frames of the human body using a single device in a top-view configuration, with the subjects located under the device inside a room. Features extracted from depth frames train a classifier based on a binary support vector machine learning algorithm. The dataset includes 32 falls and 8 activities considered for comparison, for a total of 800 sequences performed by 20 adults. The system showed an accuracy of 98.6% and only one false positive.
Phenol-Formaldehyde Resin for Optical-Chemical Temperature Sensing
Authors: Claucherty Steven , Sakaue Hirotaka
Published: May 2018

The application of phenol-formaldehyde (PF) resin as an optical temperature sensor is investigated. Recent developments in optical luminescent sensors allow for global measurements to be made over the surface of a test article, extending beyond conventional point measurements. Global temperature distributions are particularly helpful when validating computational models or when mapping temperature over complex geometries, and can be used to calculate surface heat flux values. Temperature-sensitive paint (TSP) is a novel chemical approach to obtaining these global temperature measurements, but there are still challenges to overcome to make it a reliable tool. A sensor with a wide range of temperature sensitivity is desired to provide the maximum amount of utility, especially for tests spanning large temperature gradients. Naturally luminescent materials such as PF resin provide an attractive alternative to chemical sensor coatings, and PF resin is studied for this reason. Static tests of different PF resin samples are conducted using two binder materials to strengthen the material: cloth and paper. The material shows temperature sensitivities up to −0.8%/K, demonstrating the usefulness of PF resin as a temperature sensor.
Do Factory Audits Improve International Labor Standards? An Examination of Voluntary Corporate Labor Regulations in Global Production Networks
Authors: Sanders Scott R. , Cope Michael R. , Pulsipher Elizabeth R.
Published: May 2018

This research examined the effects of voluntary factory audits on labor conditions. Sometimes referred to as corporate social responsibility (CSR) codes of conduct, corporations impose voluntary labor standards coupled with regular auditing to help ensure the protection of workers throughout their global production networks (GPNs). While some believe that auditing factories ensures that CSR codes of conduct are followed and helps private corporations promote higher labor standards, others argue that factory audits have little effect on labor standards at the factory level. Using unique panel data of internal factory audit reports of factories in four Southeast Asian countries between 2003 and 2010, this paper sought to understand whether voluntary GPN audits improve labor standards at the factory level. The results showed that a factory’s number of audits between 2003 and 2010 did not improve factory working conditions significantly and that the local neighborhood in which a factory is located has a greater effect on changes in factory audit scores. These findings suggest that CSR codes of conduct and auditing alone are not sufficient to improve labor standards in GPNs. Rather, joint private-public collaboration is needed to improve labor conditions for workers in the global south.
Knee Angle and Stride Length in Association with Ball Speed in Youth Baseball Pitchers
Authors: Van Trigt Bart , Schallig Wouter , Van der Graaff Erik , Hoozemans Marco J. M. , Veeger Dirkjan
Published: May 2018

The purpose of this study was to determine whether stride length and knee angle of the leading leg at foot contact, at the instant of maximal external rotation of the shoulder, and at ball release are associated with ball speed in elite youth baseball pitchers. In this study, fifty-two elite youth baseball pitchers (mean age 15.2 SD (standard deviation) 1.7 years) pitched ten fastballs. Data were collected with three high-speed video cameras at a frequency of 240 Hz. Stride length and knee angle of the leading leg were calculated at foot contact, maximal external rotation, and ball release. The associations between these kinematic variables and ball speed were separately determined using generalized estimating equations. Stride length as percentage of body height and knee angle at foot contact were not significantly associated with ball speed. However, knee angles at maximal external rotation and ball release were significantly associated with ball speed. Ball speed increased by 0.45 m/s (1 mph) with an increase in knee extension of 18 degrees at maximal external rotation and 19.5 degrees at ball release. In conclusion, more knee extension of the leading leg at maximal external rotation and ball release is associated with higher ball speeds in elite youth baseball pitchers.
The Sustainability of Agricultural Development in China: The Agriculture–Environment Nexus
Authors: Yu Jialing , Wu Jian
Published: May 2018

The article aims to provide an overview of China’s agricultural development and itssustainability by focusing on the agriculture–environmental nexus. We first review literatureregarding trends in agricultural development and driving forces. China has made impressiveprogress at providing food for 22% of the world’s population. At the same time, severe environmentalimpacts have been incurred which not only affect future food security but also have impacts on othersocio-economic aspects. The agricultural policies that have been put into practice have direct orindirect impacts on such environmental outcomes. We review the impacts of agricultural policiesas well as conservation policies, their effectiveness, some unintended consequences and conflicts.The article concludes that technology and institutional innovation in China should emphasize moreintegrated sustainable development considering the agriculture–environment nexus, instead ofsetting incoherent and sometimes incompatible policy goals for each separate side.
Finding CreativeVoice: Applying Arts-Based Research in the Context of Biodiversity Conservation
Authors: Rivera Lopez Flor , Wickson Fern , Hausner Vera Helene
Published: May 2018

The integration of creative arts–based methods into scientific research offers a host of advantages, including the ability to capture the complex texture of lived experience, explore interconnections between nature and culture, support nonhierarchical relations, and communicate insights in engaging and empowering new ways. In this article, we describe a new method—CreativeVoice—integrating the creative arts and qualitative research, which we developed and applied in a context of pursuing community-based conservation of agricultural biodiversity. We developed CreativeVoice as an integrative method to help us understand the local contexts, cultures, and perspectives from community members of different ages and genders, in two contrasting farming communities in Oaxaca, Mexico. CreativeVoice effectively adapts and extends the Photovoice method so as to retain its benefits but address some of its limitations. This includes allowing participants to choose a genre of artistic expression connected to their own specific individual or cultural contexts and providing the capacity to move beyond capturing present-day realities to directly bring in connections to the past and visions for the future. This article describes both the CreativeVoice approach and the significant value of integrating arts-based methods into research for advancing sustainability.
What Makes an Old Market Sustainable? An Empirical Analysis on the Economic and Leisure Performances of Traditional Retail Markets in Seoul
Authors: Yi Yun-Myong , Gim Tae-Hyoung
Published: May 2018

Traditional retail markets have long been the center for urban vitality, yet they have been under threat of advancing superstores run by corporate retailers. Studies have attempted to identify the competitiveness of the markets, but empirical evidence is not sufficient for presenting which factors contribute to the maintenance of a traditional market’s economic vitality. In South Korea, urban policies have been directed to revitalizing the markets, but their effectiveness has been questioned. This study aims to fill this void by examining traditional markets in Seoul with multiple regression on (1) the revenue and (2) the volume of customers and with negative binomial regression on (3) the popularity measured by the number of blog posts on the markets. Using a comprehensive set of variables, this paper finds that investments in physical infrastructure (p < 0.000) and organizational/operational capacities (p < 0.008 and p < 0.094) make a significant contribution to the economic vitality. Among product categories, the ratios of perishable food stores were found to be significant (p < 0.000) as well as those of food shops and vendors (p < 0.030). On the other hand, extending convenient facilities and anchor stores would reduce the revenue in the short term. In addition, traditional markets that are recognized as popular destinations may not necessarily be profitable. In this vein, attention should be paid to this mismatch when a strategy is deliberated to transform a market into a tourist attraction.
The Influence of Farmers’ Livelihood Strategies on Household Energy Consumption in the Eastern Qinghai–Tibet Plateau, China
Authors: Zhao Xueyan , Zhao Haili , Jiang Lu , Lu Chenyu , Xue Bing
Published: May 2018

As an essential factor for sustainable development, energy plays a very important role in sustaining a modern lifestyle, particularly in poor rural areas. Considering that farmers’ livelihood in such areas is enormously dependent on services provided by environmental resources, it makes sense to investigate the relationships and interactions between farming households’ livelihood strategies and their energy consumption. The findings and outcomes would be expected to contribute to the body of knowledge and benefit local policy-making toward sustainable transformation in the long run. Taking Gannan as an example, this study employed a participatory rural appraisal approach, with first-hand data mainly from field surveys, using a stratified random sampling method to illustrate the influence of farmers’ livelihood strategies for household energy consumption in the eastern Qinghai–Tibet Plateau, China. Seven townships in Gannan were covered, three of them in pure pastoral areas, two in farming-pastoral areas, and two in farming areas. From these, 230 households were selected as study samples, with a valid return of 217 questionnaires, among which 78 came from pure pastoral areas, 60 from farming-pastoral areas, and 79 from farming areas. The results show that livelihood has a significant impact on farmers’ household energy consumption patterns, and increasing family income level and education level and improving the availability of commodity energy resources will help farmers reduce the proportion of biomass energy consumption and increase the proportion of commodity energy consumption. Furthermore, measures such as developing nonagricultural industries, improving the energy infrastructure, and enhancing farmers’ energy-saving awareness should be seriously considered to optimize farmers’ living energy consumption patterns in these poverty-stricken and eco-frangible regions.
The Development and Use of Sustainability Criteria in SuRF-UK’s Sustainable Remediation Framework
Authors: Bardos R. , Thomas Hayley , Smith Jonathan , Harries Nicola , Evans Frank , Boyle Richard , Howard Trevor , Lewis Richard , Thomas Alan , Haslam Angela
Published: May 2018

Sustainability considerations have become widely recognised in contaminated land management and are now accepted as an important component of remediation planning and implementation around the world. The Sustainable Remediation Forum for the UK (SuRF-UK) published guidance on sustainability criteria for consideration in drawing up (or framing) assessments, organised across 15 “headline” categories, five for the environment element of sustainability, five for the social, and five for the economic. This paper describes how the SuRF-UK indicator guidance was developed, and the rationale behind its structure and approach. It describes its use in remediation option appraisal in the UK, and reviews the international papers that have applied or reviewed it. It then reviews the lessons learned from its initial use and the opinions and findings of international commentators, and concludes with recommendations on how the indicator categories might be further refined in the future. The key findings of this review are that the SuRF-UK framework and indicator guidance is well adopted into practice in the UK. It is widely recognised as the most appropriate mechanism to support sustainability-based decision making in contaminated land decision making. It has influenced the development of other national and international guidance and standards on sustainable remediation. However, there is room for some fine tuning of approach based on the lessons learned during its application.
Leading El-Niño SST Oscillations around the Southern South American Continent
Authors: Hsu Yu-Chen , Lee Chung-Pan , Wang You-Lin , Wu Chau-Ron , Lui Hon-Kit
Published: May 2018

The inter-annual variations in the sea surface temperatures (SSTs) of the tropical and subtropical Pacific Ocean have been widely investigated, largely due to their importance in achieving the sustainable development of marine ecosystems under a changing climate. The El Niño-Southern Oscillation (ENSO) is a widely recognized variability. In the subpolar region in the southern hemisphere, the Antarctic Circumpolar Current (ACC) is one of the main sources of the Peru Current. A change in the SST in the Southern Ocean may change the physical properties of the seawater in the tropical and subtropical Pacific Ocean. However, the variations in the SST in the Southern Ocean have rarely been addressed. This study uses a 147-year (1870–2016) dataset from the Met Office Hadley Centre to show that the SST anomalies (SSTAs) in the oceans west and east of South America and the Antarctic Peninsula have strong positive (R = 0.56) and negative (R = −0.67) correlations with the Niño 3.4 SSTA, respectively. Such correlations are likely related to the changes in circulations of the ACC. We further show that, statistically, the temporal variations in the SSTAs of the ACC lead the Niño 3.4 SSTA by four to six months. Such findings imply that change in the strength of ENSO or circulation under the changing climate could change the climate in regions at higher latitudes as well.
An Assessment of the Drivers and Barriers for the Deployment of Urban Phosphorus Recovery Technologies: A Case Study of The Netherlands
Authors: De Boer Marissa A. , Romeo-Hall Anjelika G. , Rooimans Tomas M. , Slootweg J. Chris
Published: May 2018

Phosphorus (P), being one of the building blocks of life, is essential for a multitude of applications, primarily for fertilizer usage. Sustainable management of phosphorus is becoming increasingly important in light of adverse environmental effects, ambiguous reserves, increasing global demand and unilateral dependence. Recovery of phosphorus from the biggest loss stream, communal wastewater, has the potential to tackle each of these problems. The implementation of phosphorus recovery technologies at wastewater treatment plants is not widespread, despite prolonged efforts primarily done by researchers over the past decade. This study aimed to assess the drivers and barriers of a phosphorus recovery transition. Several key stakeholders involved in this transition in The Netherlands were interviewed. The Netherlands was taken as a case study, since it serves as a frontrunner in the implementation of phosphorus recovery technologies. This study shows that the main barriers from the point of view of fertilizer companies are the different and unclear characteristics of the phosphorus recovery product struvite compared to common fertilizers. Moreover, the end-of-waste status of struvite is mentioned as a prominent barrier for a phosphorus transition, since it hinders free market trade. Many water boards indicate that the main barrier is the high investment cost with an uncertain return on investment for onsite struvite recovery processes. The specified main driver for water boards for onsite struvite phosphorus recovery technology is the reduction of maintenance costs, and for phosphorus recovery from sewage sludge ash, the low organic pollutant in the P recovery product.