bluuebunny/crossref_metadata_2025 huggingface dataset:
Virulence Traits and Azole Resistance in Korean Candida auris Isolates
Authors: Byun Seung A. , Kwon Yong Jun , Lee Ga Yeong , Choi Min Ji , Jeong Seok Hoon , Kim Dokyun , Choi Min Hyuk , Kee Seung-Jung , Kim Soo Hyun , Shin Myung Geun , Won Eun Jeong , Shin Jong Hee
Published: September 2023

We analyzed the virulence traits and azole resistance mechanisms of 104 Candida auris isolates collected from 13 Korean hospitals from 1996 to 2022. Of these 104 isolates, 96 (5 blood and 91 ear isolates) belonged to clade II, and 8 (6 blood and 2 other isolates) belonged to clade I. Fluconazole resistance (minimum inhibitory concentration ≥32 mg/L) was observed in 68.8% of clade II and 25.0% of clade I isolates. All 104 isolates were susceptible to amphotericin B and three echinocandins. In 2022, six clade I isolates indicated the first nosocomial C. auris cluster in Korea. Clade II C. auris isolates exhibited reduced thermotolerance at 42 °C, with diminished in vitro competitive growth and lower virulence in the Galleria mellonella model compared to non-clade II isolates. Of the 66 fluconazole-resistant clade II isolates, several amino acid substitutions were identified: Erg11p in 14 (21.2%), Tac1Ap in 2 (3.0%), Tac1Bp in 62 (93.9%), and Tac1Bp F214S in 33 (50.0%). Although there were a limited number of non-clade II isolates studied, our results suggest that clade II C. auris isolates from Korean hospitals might display lower virulence traits than non-clade II isolates, and their primary fluconazole resistance mechanism is linked to Tac1Bp mutations.
Optimizing Soil Moisture Retrieval: Utilizing Compact Polarimetric Features with Advanced Machine Learning Techniques
Authors: Dabboor Mohammed , Atteia Ghada , Alnashwan Rana
Published: September 2023

Soil moisture plays a crucial role in various environmental processes and is essential for agricultural management, hydrological modeling, and climate studies. Synthetic Aperture Radar (SAR) remote sensing presents significant potential for estimating soil moisture due to its ability to operate in all weather conditions and provide day-and-night imaging capabilities. Among the SAR configurations, the Compact Polarimetric (CP) mode has gained increasing interest as it relaxes system constraints, improves coverage, and enhances target information compared to conventional dual polarimetric SAR systems. This paper introduces a novel approach for soil moisture retrieval utilizing machine learning algorithms and CP SAR features. The CP SAR features are derived from a series of RADARSAT Constellation Mission (RCM) CP SAR imagery acquired over Canadian experimental sites equipped with Real-Time In Situ Soil Monitoring for Agriculture (RISMA) stations. This study employs a diverse dataset of compact polarimetric SAR features and corresponding ground truth soil moisture measurements for training and validation purposes. The results of our study achieved a Root Mean Square Error (RMSE) of 6.88% with a coefficient of determination R2 equal to 0.60, which corresponds to a correlation R between true and predicted soil moisture values of 0.75, using optimized Ensemble Learning Regression (ELR) with a decision-tree-based model. These results improved, yielding an RMSE of 5.67% and an R2 equal to 0.73 (R = 0.85), using an optimized Gaussian Process Regression (GPR) model.
Evaluation of the Smart City and Analysis of Its Spatial–Temporal Characteristics in China: A Case Study of 26 Cities in the Yangtze River Delta Urban Agglomeration
Authors: Gu Tiantian , Liu Shuyu , Liu Xuefan , Shan Yujia , Hao Enyang , Niu Miaomiao
Published: September 2023

The smart city is recognized as a potent instrument for creating efficient urban environments and improving the quality of life of urban residents. However, there is an absence of research establishing a comprehensive evaluation model for the smart cities (SCs) and focusing on their spatiotemporal analysis. Thus, a comprehensive evaluation framework was developed and applied to 26 cities in the Yangtze River Delta Urban Agglomeration (YRDUA) in China from 2017 to 2020 to assess the smart city level (SCL) in China and analyze these cities’ spatial–temporal characteristics. The results indicated the following: (1) The overall SCL in the YRDUA has exhibited sustainable improvement, and the gap between cities is gradually narrowing. (2) The SCL of the YRDUA exhibits a higher SCL in the east and a lower SCL in the west of the YRDUA. The global spatial correlation of the SCL was random. Nantong, Hefei, Jiaxing, Zhoushan, Chizhou, Tongling, and Wuhu showed significant local spatial correlation. (3) The comprehensive evaluation framework is applicable for analyzing the SCs in China, and this framework can also be extended to other countries. Pertinent recommendations are put forth to enhance the SCL through the formulation of policies and fostering intercity collaboration. This research not only enriches the theoretical research on smart city evaluation but also clarifies the spatial–temporal characteristics of the SCs in China, thereby providing valuable insights that can foster sustainable smart city development.
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
Authors: Ozturk Alpaslan , Agbektas Tugba , Huseynzada Alakbar , Guliyev Ruslan , Ganbarova Rana , Hasanova Ulviyya , Tas Ayca , Erkan Sultan , Zontul Cemile , Inandiklioglu Nihal , Silig Yavuz
Published: September 2023

We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were synthesized by a condensation reaction and received compounds were characterized by 1H and 13C NMR spectroscopy methods. Furthermore, they were applied to the AGS cell line at eight different concentrations (0.1–50 µg/mL). Anticancer activities were determined using the MTT method. Expression levels of ATR, ERCC1, TOP2A, and ABCB1 genes were determined by the RT-PCR method. Biochemical parameters were also examined. The interaction of proteins with other proteins was investigated with the String v11 program. The IC50 values of compounds 1, 2, and 3 obtained after 72 h were 23.10, 8.93, and 1.58 µg/mL, respectively. The results demonstrate that the cytotoxic activity of compound 3 on AGS cancer cells is higher in comparison with other molecules. It was determined that the expression levels of ATR, TOP2A, and ABCB1 genes in compounds 1, 2, and 3 were decreased compared to the control group. In addition, it was determined that ERCC1 gene expression increased in compound 3, decreased in compound 2, and remained unchanged in compound 1 (p < 0.001). In AGS gastric cancer cells, a 64% decrease was detected for GST levels in compound 1, while a 38% decrease in GSH levels in compound 2. In addition, compounds 1–3 were examined at the molecular level with computational techniques and the docking studies revealed 4LN0 as a target protein.
Unraveling the Power of Topical Inhaled Steroids in Treating Laryngeal Granulomas: A Systematic Review
Authors: Alarfaj Abdullah A.
Published: September 2023

The efficacy of inhaled steroids in the treatment of airway laryngeal granuloma is an important topic of research, given the increasing prevalence of this condition. In this systematic review, we aimed to evaluate the existing evidence on the effectiveness of inhaled steroids in treating airway granuloma. The search was performed in several electronic databases including PubMed, Embase, and the Cochrane Library. We included all relevant studies that were published in the English language between 2005 and 2021. A total of nine studies were eligible for inclusion in our systematic review, including one randomized controlled trial, one case-control study, and seven retrospective studies. The results of our review suggest that inhaled steroids may be effective in treating airway granuloma, but more research is needed to confirm these findings. The limitations of the included studies, such as small sample sizes, inconsistent study designs, and a lack of long-term follow-up, suggest that additional research is needed to confirm the effectiveness of inhaled steroids in treating airway granuloma. Overall, this systematic review highlights the need for further studies to confirm the effectiveness of inhaled steroids in treating airway granuloma.
Challenges and Solutions in the Management of Hepatocellular Carcinoma Associated with Non-Alcoholic Fatty Liver Disease
Authors: Cadar Ramona , Lupascu Ursulescu Corina , Vasilescu Alin Mihai , Trofin Ana Maria , Zabara Mihai , Rusu-Andriesi Delia , Ciuntu Bogdan , Muzica Cristina , Lupascu Cristian Dumitru
Published: September 2023

Non-alcoholic fatty liver disease (NAFLD) has gained attention in the last few years due to its increasing prevalence worldwide becoming a global epidemic. The increasing incidence of NAFLD and the concurrent increase in the number of hepatocellular carcinoma (HCC) cases at a global level is a matter of concern. HCC has several risk factors, of which NAFLD and its associated metabolic disturbances—type 2 diabetes mellitus, obesity, and dyslipidemia—are of great interest due to their accelerating rise in incidence worldwide. There is a high amount of data derived from basic and clinical studies that reveal the molecular pathways that drive NAFLD-associated HCC. Based on these findings, new prevention, surveillance, and treatment strategies are emerging. However, current data on treatment modalities in NAFLD-associated HCC are still scarce, though the results from non-NAFLD HCC studies are promising and could provide a basis for a future research agenda to address NAFLD/NASH patients. Clinicians should carefully assess all the clinical and radiological parameters and establish a prognosis based on the Barcelona Clinic Liver Cancer classification and discuss in a multidisciplinary team the treatment strategy. The specific factors associated with NAFLD-associated HCC which can have a negative impact on survival even in patients with early HCC, such as cardiovascular disease, type 2 diabetes, and obesity, should be taken into consideration. This review aims to discuss the latest recommendations regarding the diagnosis and treatment of NAFLD-associated HCC and the remaining challenges.
Photonic Crystal Flip-Flops: Recent Developments in All Optical Memory Components
Authors: Pugachov Yonatan , Gulitski Moria , Malka Dror
Published: September 2023

This paper reviews recent advancements in all-optical memory components, particularly focusing on various types of all-optical flip-flops (FFs) based on photonic crystal (PC) structures proposed in recent years. PCs, with their unique optical properties and engineered structures, including photonic bandgap control, enhanced light–matter interaction, and compact size, make them especially suitable for optical FFs. The study explores three key materials, silicon, chalcogenide glass, and gallium arsenide, known for their high refractive index contrast, compact size, hybrid integration capability, and easy fabrication processes. Furthermore, these materials exhibit excellent compatibility with different technologies like CMOS and fiber optics, enhancing their versatility in various applications. The structures proposed in the research leverage mechanisms such as waveguides, ring resonators, scattering rods, coupling rods, edge rods, switches, resonant cavities, and multi-mode interference. The paper delves into crucial properties and parameters of all-optical FFs, including response time, contrast ratio, and operating wavelength. Optical FFs possess significant advantages, such as high speed, low power consumption, and potential for integration, making them a promising technology for advancing optical computing and optical memory systems.
Equivalent Noise Analysis and Modeling for a Magnetic Tunnel Junction Magnetometer with In Situ Magnetic Feedback
Authors: Dou Aiyu , Bai Ru , Sun Yucheng , Tu Jiakun , Kou Chuanjia , Xie Xin , Qian Zhenghong
Published: September 2023

Magnetic tunnel junction (MTJ) sensors have been one of the excellent candidates for magnetic field detection due to their high sensitivity and compact size. In this paper, we design a magnetometer with in situ magnetic feedback consisting of an MTJ sensor. To analyze and evaluate the detectivity of the MTJ magnetometer, a noise model of the MTJ sensor in the magnetometer without magnetic feedback is first developed. Then, the noise model of the MTJ magnetometer with in situ magnetic feedback is also established, including the noises of the MTJ sensor and the signal conditioning circuit, as well as the feedback circuit. The equivalent noise model of the MTJ magnetometer with in situ magnetic feedback is evaluated through nonlinear fitting for the noise voltage spectrum. Although the noise generated by the MTJ sensor is much greater than that of the signal conditioning circuit, the noise introduced by the feedback coils into the MTJ sensor is slightly more than twice that generated by the MTJ sensor itself. The measurement results show that the detectivity of the MTJ magnetometer with in situ magnetic feedback reaches 526 pT/Hz1/2 at 10 Hz. The equivalent noise analysis method presented in this paper is suitable for the detectivity analysis of magnetometers with magnetic feedback.
Optimal Topology of Vision Transformer for Real-Time Video Action Recognition in an End-To-End Cloud Solution
Authors: Sarraf Saman , Kabia Milton
Published: September 2023

This study introduces an optimal topology of vision transformers for real-time video action recognition in a cloud-based solution. Although model performance is a key criterion for real-time video analysis use cases, inference latency plays a more crucial role in adopting such technology in real-world scenarios. Our objective is to reduce the inference latency of the solution while admissibly maintaining the vision transformer’s performance. Thus, we employed the optimal cloud components as the foundation of our machine learning pipeline and optimized the topology of vision transformers. We utilized UCF101, including more than one million action recognition video clips. The modeling pipeline consists of a preprocessing module to extract frames from video clips, training two-dimensional (2D) vision transformer models, and deep learning baselines. The pipeline also includes a postprocessing step to aggregate the frame-level predictions to generate the video-level predictions at inference. The results demonstrate that our optimal vision transformer model with an input dimension of 56 × 56 × 3 with eight attention heads produces an F1 score of 91.497% for the testing set. The optimized vision transformer reduces the inference latency by 40.70%, measured through a batch-processing approach, with a 55.63% faster training time than the baseline. Lastly, we developed an enhanced skip-frame approach to improve the inference latency by finding an optimal ratio of frames for prediction at inference, where we could further reduce the inference latency by 57.15%. This study reveals that the vision transformer model is highly optimizable for inference latency while maintaining the model performance.
Sonographic Phrenic Nerve Changes in Amyotrophic Lateral Sclerosis
Authors: Laucius Ovidijus , Drūteika Justinas , Balnytė Renata , Petrikonis Kęstutis , Ališauskienė Miglė , Vaitkus Antanas
Published: September 2023

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects both the upper and lower motor neurons in the nervous system, causing muscle weakness and severe disability. The progressive course of the disease reduces the functional capacity of the affected patients, limits daily activities, and leads to complete dependence on caregivers, ultimately resulting in a fatal outcome. Respiratory dysfunction mostly occurs later in the disease and is associated with a worse prognosis. Forty-six participants were included in our study, with 23 patients in the ALS group and 23 individuals in the control group. The ultrasound examination of the phrenic nerve (PN) was performed by two authors using a high-resolution “Philips EPIQ 7” ultrasound machine with a linear 4–18 MHz transducer. Our study revealed that the phrenic nerve is significantly smaller on both sides in ALS patients compared to the control group (p < 0.001). Only one significant study on PN ultrasound in ALS, conducted in Japan, also showed significant results (p < 0.00001). These small studies are particularly promising, as they suggest that ultrasound findings could serve as an additional diagnostic tool for ALS.
Effectiveness of Intranasal Analgesia in the Emergency Department
Authors: Zanza Christian , Saglietti Francesco , Giamello Jacopo Davide , Savioli Gabriele , Biancone Davide Maria , Balzanelli Mario Giosuè , Giordano Benedetta , Trompeo Anna Chiara , Longhitano Yaroslava
Published: September 2023

In the Emergency Department (ED), pain is one of the symptoms that are most frequently reported, making it one of the most significant issues for the emergency physician, but it is frequently under-treated. Intravenous (IV), oral (PO), and intramuscular (IM) delivery are the standard methods for administering acute pain relief. Firstly, we compared the safety and efficacy of IN analgesia to other conventional routes of analgesia to assess if IN analgesia may be an alternative for the management of acute pain in ED. Secondly, we analyzed the incidence and severity of adverse events (AEs) and rescue analgesia required. We performed a narrative review-based keywords in Pubmed/Medline, Scopus, EMBASE, the Cochrane Library, and Controlled Trials Register, finding only twenty randomized Clinical trials eligible in the timeline 1992–2022. A total of 2098 patients were analyzed and compared to intravenous analgesia, showing no statistical difference in adverse effects. In addition, intranasal analgesia also has a rapid onset and quick absorption. Fentanyl and ketamine are two intranasal drugs that appear promising and may be taken simply and safely while providing effective pain relief. Intravenous is simple to administer, non-invasive, rapid onset, and quick absorption; it might be a viable choice in a variety of situations to reduce patient suffering or delays in pain management.
Relation of Jump and Change of Direction Inter-Limb Asymmetries with Fitness in Youth Male Soccer Players
Authors: Michailidis Yiannis
Published: September 2023

Background and Objectives: Asymmetries between the lower limbs were evaluated by both researchers and practitioners as they seem to be related to the occurrence of injuries and the effect on performance. The purposes of this study were to (a) detect asymmetries of the lower limbs using a unilateral jump (single-leg countermovement jump (SLCMJ)) and 505 agility test, and (b) examine asymmetry effects on fitness (acceleration, speed, squat jump, Illinois agility test), in U16 youth male soccer players. Materials and Methods: Twenty U16 soccer players performed an SLCMJ and a 505 test to calculate the asymmetry index. They also performed the above fitness tests. The difference between the lower limbs was tested using the paired samples t-test (dominant vs. non-dominant). The correlations between the asymmetries of the lower extremities with the performance indicators were tested using the Pearson’s correlation test. The level of significance was set at p < 0.05. Results: The lower limbs differed significantly in the SLCMJ and 505 tests (p < 0.05). The only correlation was between the asymmetry in SLCMJ and performance in SJ (r = −0.641, p = 0.002). Asymmetries did not affect performance on most fitness tests. Conclusions: The two asymmetry tests identified asymmetries in different limbs. This indicates the variability in asymmetries and the need for specialized tests depending on the kinematic chain. The asymmetries observed should be eliminated using individualized training programs so that athletes are protected from injuries and from the possible negative impact on performance. Also, the detection of asymmetries in developmental age offers a greater time period for their elimination before the athlete enters professional sports.
Changes in the Lipid Metabolism of the Longissimus thoracis Muscle in Bulls When Using Different Feeding Strategies during the Growing and Finishing Phases
Authors: Torrecilhas Juliana Akamine , Pereira Guilherme Luis , Vito Elias San , Fiorentini Giovani , Ramirez-Zamudio Germán Darío , Fonseca Larissa Simielli , Torres Rodrigo de Nazaré Santos , Simioni Tiago Adriano , Duarte Juliana Messana , Machado Neto Otavio Rodrigues , Curi Rogério Abdallah , Chardulo Luis Artur Loyola , Baldassini Welder Angelo , Berchielli Telma Teresinha
Published: September 2023

The objective was to evaluate the supplementation strategy’s effect on beef cattle during the growing phase and two systems during the finishing phase. One hundred and twenty young bulls were randomly divided in a 2 × 2 factorial design to receive either mineral (ad libitum) or protein + energy (3 g/kg body weight (BW)/day) during the growing phase and pasture plus concentrate supplementation (20 g/kg BW/day) or feedlot (25:75% corn silage:concentrate) during the finishing phase. Feedlot-fed bulls had meat (Longissimus thoracis—LT) with a higher content of lipids and saturated and monounsaturated fatty acids and a greater upregulation of stearoyl-CoA desaturase and sterol regulatory element-binding protein-1c than animals that fed on pasture (p < 0.05). On the other hand, pasture-fed bulls had meat with a higher content of α-linoleic acid, linolenic acid, and n6 and a greater n6:n3 ratio compared to the feedlot-fed group (p < 0.05). In addition, meat from pasture-fed bulls during the finishing phase had 17.6% more isocitrate dehydrogenase enzyme concentration than the feedlot group (p = 0.02). Mineral-fed and pasture-finished bulls showed down-regulation of peroxisome proliferator-activated receptor gamma (p < 0.05), while the bulls fed protein + energy and finished in the feedlot had higher carnitine palmitoyltransferase 2 expression (p ≤ 0.013). In conclusion, mineral or protein + energy supplementation in the growing does not affect the fatty acid composition of intramuscular fat of LT muscle. In the finishing phase, feeding bulls in the feedlot upregulates the lipogenic genes and consequently improves the intramuscular fat content in the meat.
Location of Carbonate Ions in Metal-Doped Carbonated Hydroxylapatites
Authors: Yoder Claude H. , Goodman Julia T.
Published: September 2023

The environment model for the description of the location of carbonate ions in apatites predicts that approximately half of the carbonate occupies the apatite channel. This model relies on the influence of entities surrounding the carbonate on its IR spectrum and can be used to determine how various substituents affect the location and structure of that ion. Careful deconvolution (peak-fitting) of the asymmetric carbonate IR region was used to determine the percentage of A-type (channel) ions, A′-type (channel with either a Ca2+ vacancy or substitution of Na+ for Ca2+) ions, and B-type (substitution for phosphate) ions. In our previous applications of this model, we have looked at the effect of alkali metal ions, such as sodium, lithium, and potassium, the ammonium ion, and the rare earth europium ion. In the present work, we explore the incorporation of the first-row transition metal ions and find that they have little effect on the location of the carbonate ion. Like the un-substituted carbonated apatite, these apatites contain about half of the carbonate in the channel, at least in derivatives that contain up to half a mole of the metal ion per mole of apatite. Attempts to incorporate greater amounts of metal ions by aqueous ion-combination reactions generally lead to lower-resolution XRD patterns and IR spectra that produce greater uncertainties in the peak-fitting modeling.
Photobiomodulation and Growth Factors in Dentistry: A Systematic Review
Authors: Dipalma Gianna , Inchingolo Angelo Michele , Patano Assunta , Palumbo Irene , Guglielmo Mariafrancesca , Trilli Irma , Netti Anna , Ferrara Irene , Viapiano Fabio , Inchingolo Alessio Danilo , Favia Gianfranco , Dongiovanni Leonardo , Palermo Andrea , Inchingolo Francesco , Limongelli Luisa
Published: September 2023

Photobiomodulation, or Low-Level Laser Therapy, is a therapeutic technique that can be applied in tissue regenerative surgery. By stimulating the cellular compartment, photobiomodulation promotes cell proliferation, enabling tissue restoration after dental extractions, periodontal surgical treatments, or the management of traumatic oral injuries. On the other hand, Platelet-Rich Plasma (PRP) or Platelet-Rich Fibrin (PRF) therapy is particularly effective in providing a source of growth factors that enhance tissue healing. Authors carried out a Systematic Review following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines by searching PubMed, Web of Science (WoS), Scopus, and Cochrane Library databases, using the combination of the following keywords: (“low laser therapy”) AND (“growth factors”) AND (dent* OR oral) and (“photobiomodulation”) AND (“growth factors”) AND (dent* OR oral). A total of 10 publications were deemed eligible for qualitative analysis. The evidence analyzed confirms that the use of photobiomodulation and PRP/PRF (alone or in combination) can stimulate tissue regeneration, allowing for a reduction in postoperative inflammation, wound healing, and new tissue formation. Moreover, these effects are strictly dependent on the intrinsic characteristics of the individual patient, the needs, and the clinical assessment of the practitioner who will appropriately direct the treatment. Furthermore, it is necessary to investigate with evidence-based methodologies (Evidence-based Medicine, EBM) which types of patients and/or lesions are more susceptible to treatment with these tools, as well as to understand the best ways of using (alone or in combination) these important and cutting-edge therapeutic options.
An Approach for Plant Leaf Image Segmentation Based on YOLOV8 and the Improved DEEPLABV3+
Authors: Yang Tingting , Zhou Suyin , Xu Aijun , Ye Junhua , Yin Jianxin
Published: September 2023

Accurate plant leaf image segmentation provides an effective basis for automatic leaf area estimation, species identification, and plant disease and pest monitoring. In this paper, based on our previous publicly available leaf dataset, an approach that fuses YOLOv8 and improved DeepLabv3+ is proposed for precise image segmentation of individual leaves. First, the leaf object detection algorithm-based YOLOv8 was introduced to reduce the interference of backgrounds on the second stage leaf segmentation task. Then, an improved DeepLabv3+ leaf segmentation method was proposed to more efficiently capture bar leaves and slender petioles. Densely connected atrous spatial pyramid pooling (DenseASPP) was used to replace the ASPP module, and the strip pooling (SP) strategy was simultaneously inserted, which enabled the backbone network to effectively capture long distance dependencies. The experimental results show that our proposed method, which combines YOLOv8 and the improved DeepLabv3+, achieves a 90.8% mean intersection over the union (mIoU) value for leaf segmentation on our public leaf dataset. When compared with the fully convolutional neural network (FCN), lite-reduced atrous spatial pyramid pooling (LR-ASPP), pyramid scene parsing network (PSPnet), U-Net, DeepLabv3, and DeepLabv3+, the proposed method improves the mIoU of leaves by 8.2, 8.4, 3.7, 4.6, 4.4, and 2.5 percentage points, respectively. Experimental results show that the performance of our method is significantly improved compared with the classical segmentation methods. The proposed method can thus effectively support the development of smart agroforestry.
Recent Progress of the Vat Photopolymerization Technique in Tissue Engineering: A Brief Review of Mechanisms, Methods, Materials, and Applications
Authors: Li Ying , Zhang Xueqin , Zhang Xin , Zhang Yuxuan , Hou Dan
Published: September 2023

Vat photopolymerization (VP), including stereolithography (SLA), digital light processing (DLP), and volumetric printing, employs UV or visible light to solidify cell-laden photoactive bioresin contained within a vat in a point-by-point, layer-by-layer, or volumetric manner. VP-based bioprinting has garnered substantial attention in both academia and industry due to its unprecedented control over printing resolution and accuracy, as well as its rapid printing speed. It holds tremendous potential for the fabrication of tissue- and organ-like structures in the field of regenerative medicine. This review summarizes the recent progress of VP in the fields of tissue engineering and regenerative medicine. First, it introduces the mechanism of photopolymerization, followed by an explanation of the printing technique and commonly used biomaterials. Furthermore, the application of VP-based bioprinting in tissue engineering was discussed. Finally, the challenges facing VP-based bioprinting are discussed, and the future trends in VP-based bioprinting are projected.
User Re-Identification via Confusion of the Contrastive Distillation Network and Attention Mechanism
Authors: Zhang Mingming , Wang Bin , Zhu Sulei , Zhou Xiaoping , Yang Tao , Zhai Xi
Published: September 2023

With the rise of social networks, more and more users share their location on social networks. This gives us a new perspective on the study of user movement patterns. In this paper, we solve the trajectory re-identification task by identifying human movement patterns and then linking unknown trajectories to the user who generated them. Existing solutions generally focus on the location point and the location point information, or a single trajectory, and few studies pay attention to the information between the trajectory and the trajectory. For this reason, in this paper, we propose a new model based on a contrastive distillation network, which uses a contrastive distillation model and attention mechanisms to capture latent semantic information for trajectory sequences and focuses on common key information between pairs of trajectories. Combined with the trajectory library composed of historical trajectories, it not only reduces the number of candidate trajectories but also improves the accuracy of trajectory re-identification. Our extensive experiments on three real-world location-based social network (LBSN) datasets show that our method outperforms existing methods.
Biases in Stakeholder Elicitation as a Precursor to the Systems Architecting Process
Authors: Yeazitzis Taylor , Weger Kristin , Mesmer Bryan , Clerkin Joseph , Van Bossuyt Douglas
Published: September 2023

Many systems engineering projects begin with the involvement of stakeholders to aid in decision-making processes. As an application of systems engineering, systems architecture involves the documentation of stakeholder needs gathered via elicitation and the transformation of these needs into requirements for a system. Within human–machine teaming, systems architecture allows for the creation of a system with desired characteristics elicited from stakeholders involved with the project or system. Though stakeholders can be excellent sources for expert opinion, vested interests in a project may potentially bias stakeholders and impact decision-making processes. These biases may influence the design of the system architecture, potentially resulting in a system that is developed with unbalanced and misrepresented stakeholder preferences. This paper presents an activity analysis of the Stakeholder Needs and Requirements Process as described in the Systems Engineering Body of Knowledge (SEBoK) to identify potential biases associated with this elicitation process. As part of the research presented in this paper, a workshop was conducted where currently practicing systems architects provided feedback regarding perceptions of biases encountered during the elicitation process. The findings of this research will aid systems architects, developers, and users in understanding how biases may impact stakeholder elicitation within the architecting process.
DETERMINAN HIPERTENSI MASYARAKAT PESISIR DI KABUPATEN JEMBER
Authors: Mustofa Yuliana Amelia Reza , Bumi Candra
Published: September 2023

Hypertension is abnormal blood pressure. High blood pressure is often called the silent killer because this disease shows no warning. There are 2 factors cause increased morbidity and mortality rates due to hypertension, namely, factors that can be modified, such as obesity, sodium consumption, smoking, alcohol consumption, education, and employment. Factors that cannot be changed include age, gender, and family history. This study aimed to identify the determinants of hypertension in coastal communities in the working area of ​​the Cakru Community Health Center, Jember Regency. This type of research is analytic, using a cross-sectional research design. The number of samples in this study reached 111 respondents. The results of statistical analysis research using the Chi-square test showed statistical significance, namely the gender variable p-value0.032, POR= 2.478, 95%CI (1.151 – 5.336) family history p-value0.001, POR= 4.248, 95%CI (1.898 – 9.509) work p-value0.040, POR= 2.393, 95%CI (1.109 – 5.162) obesity p-value0.000, POR= 5.614, 95%CI (2.440 – 12.916) and sodium p-value0.000 POR= 10.500 95%CI (4.342 – 25,389) associated with hypertension. The results of the logistic regression analysis show that the variable that has the most influence on coastal communities in the working area of ​​the Cakru Community Health Center, Jember Regency, is sodium, which has a sig value of 0.000. The conclusion showed, there was a relationship with the variables of gender, family history, occupation, obesity, and sodium to the incidence of hypertension, and the variable that most influences the incidence of hypertension in this study is sodium.
YABANCI CİSİMLER VE DENTAL MATERYALLERİN GÖRÜNTÜ ÖZELLİKLERİNİN FARKLI GÖRÜNTÜLEME TEKNİKLERİ İLE DEĞERLENDİRİLMESİ
Authors: ERSU Nihal , KAYGISIZ YİĞİT Meryem , TANYERİ Fatma Zehra , YALVAÇ Beyza , CANGER Emin Murat
Published: September 2023

Bu çalışmanın amacı, çene yüz bölgesine penetre olabilen opak veya opak olmayan dental materyaller ve yabancı cisimlerin görüntü karakterlerinin farklı görüntüleme teknikleri ile belirlenmesi ve bu cisimlerin saptanmasında konvansiyonel radyografi ve ultrasonografi tekniklerinin kullanımının karşılaştırılmasıdır. Çalışmaya farklı opasite özellikleri gösteren, dental materyaller ve yabancı cisimlerden oluşan 15 obje dahil edildi. Objeler, bir cm ve üç cm olmak üzere iki ayrı derinlikte sığır jelatinine gömüldü. Objeler, konvansiyonel radyografi ve ultrasonografi ile görüntülendi ve görüntü özellikleri tablo halinde kaydedildi. Konvansiyonel radyografi ile objelerin opasitesi değerlendirilirken, ultrasonografi ile görünürlükleri ve posterior akustik davranışları incelendi. Konvansiyonel radyografi görüntülerinde objelerden 9 tanesi opak, 2 tanesi yarı opak, 4 tanesi non-opak görünümdeydi. Ultrasonografi ile değerlendirmede konvansiyonel radyografide görüntü elde edilemeyen objeler de dahil olmak üzere tüm objelerden görüntü elde edilebildi. Bunlardan 13 tanesi hiperekoik görünümde izlenirken; 2 tanesi izoekoik görünümde idi. Objelerin akustik davranışları incelendiğinde ise, 9 tanesinde posterior akustik gölgelenme, 1 tanesinde comet tail artefaktı ve bir tanesinde reverberasyon artefaktı gözlenirken 4 tanesinde herhangi bir artefakt bulgusu izlenmedi. Ultrasonografi, yumuşak dokuya penetre olabilen, düşük radyodensite özelliği gösteren veya konvansiyonel radyografide görüntü oluşturmayan yabancı cisimlerin saptanmasında efektif şekilde kullanılabilir.
SOLUNUM TİPİ İLE YUMUŞAK DAMAK ŞEKLİ ARASINDAKİ İLİŞKİNİN İNCELENMESİ
Authors: ÖZTÜRK Taner , MAMMADOV Elshan , SOYLU Sertan
Published: September 2023

Bu çalışmada erişkinlerdeki solunum tipi (burun veya ağız solunumu) ile yumuşak damak şekli arasındaki ilişkinin incelenmesi amaçlanmıştır. Çalışmanın materyalini Erciyes Üniversitesi Diş Hekimliği Fakültesi Ortodonti Kliniğine tedavi amacıyla başvuran ağız solunumu teşhisi konulan ortalama yaşı 22.27±2.58 yıl olan 65 birey (33 erkek, 32 kadın) ve burun (normal) solunumu yapan ortalama yaşı 21.98±3.10 yıl olan 65 bireye (30 erkek, 35 kadın) ait lateral sefalometrik radyografiler oluşturmuştur. Yumuşak damak şekli yaprak tipi, sıçan kuyruğu tipi, geniş yaprak tipi, düz çizgi, S şeklinde ve eğrilmiş tip olarak 6 kategoride sınıflandırılmıştır. İstatistiksel analizlerde Shapiro-Wilk, Mann-Whitney U, Pearson Chi-Saure ve Fisher’s Exact testleri kullanılmıştır. İstatistiksel anlamlılık değeri p<0.05 olarak kabul edilmiştir. Yumuşak damak şekli ile cinsiyet arasında anlamlı bir ilişki kurulamamıştır (p>0.05). Erkeklerde yaprak şeklindeki yumuşak damak şekli daha yüksek oranda (%30.2) bulunurken kadınlarda ise sıçan kuyruğu tipi daha yüksek oranda (%32.8) bulunmaktadır. Solunum tipi ile yumuşak damak şekli arasında anlamlı bir ilişki yoktur (p>0.05). Ağız solunumu yapanlarda sıçan kuyruğu tipi yumuşak damak şekli (%33.8) daha yüksek oranda bulunurken burun solunumu yapanlarda ise yaprak (%26.2) şeklinde yumuşak damak şeklinin yüksek oranda bulunduğu belirlenmiştir. Sonuç olarak, yumuşak damağın şekil varyasyonları ile cinsiyet ve bireyin solunum tipi (ağız veya burun) bir ilişki yoktur. Solunum tipi yumuşak damak şeklini etkilememektedir.
Satisfação dos pacientes em relação ao atendimento do sistema único de saúde no município de Juiz de Fora – MG
Authors: Carvalho Caio Alvine , Fiorillo Giovanni Oliveira , Do Carmo Mário Sérgio Simão , Vinhosa Pedro Cunha , Magalhães Rafael Murad , Dias Anna Marcella Neves , Mendes Nathália Barbosa do Espírito Santo , Laizo Artur
Published: September 2023

Introdução: O Sistema Único de Saúde (SUS) é a entidade responsável pela promoção da saúde. Este sistema apresenta algumas dificuldades por conta da amplitude no atendimento. Todavia, não se pode dizer que é ruim. Para mensurar o nível de satisfação do usuário do SUS, deve-se compreender que o aspecto “satisfação” envolve muito mais do que um simples atendimento, mas, também, como principal ponto relevante, a percepção dos usuários frente aos serviços oferecidos, infraestrutura local, acesso ao local de atendimento em questão e a qualidade dos serviços prestados, além da relevância da relação médico-paciente. Objetivo: Avaliar o nível de satisfação dos usuários do SUS no município de Juiz de Fora-MG. Métodos: Foi realizado um estudo observacional de tipo transversal a respeito da satisfação dos usuários do SUS, no município de Juiz de Fora, Minas Gerais utilizando um questionário criado especialmente para o presente estudo. Resultados: A maioria dos entrevistados (70%) avaliou o atendimento médico de forma positiva. Também foi pesquisada a satisfação dos pacientes em relação ao atendimento na recepção, em que 60% avaliaram o serviço como bom ou ótimo, 22% avaliaram como regular e 17% como ruim ou péssimo. Além disso, 77% dos entrevistados aprovaram o atendimento como um todo, desde a recepção até ao final da consulta médica. Ademais, foi constatado que 95% dos usuários do SUS relataram não haver dificuldades para chegar ao local da consulta médica, indicando que as UBS’s estão bem sinalizadas. Conclusão: Os resultados mostraram que a maioria dos usuários do SUS estava satisfeita. A satisfação do usuário do SUS envolvia não somente um atendimento corriqueiro, mas também à humanização por parte dos profissionais envolvidos no serviço.
ḫaššumaš BAYRAMI VE İKRAMLAR
Authors: BAŞ Nazan
Published: September 2023

CTH 633 katalog numaralı ḫaššumaš bayram metni A. IBoT 1.29, B. KBo 45.52(+)KUB 51.57, C. KBo 51.135, D. KBo 45.51 ve E. CHDS 5.2 nüshalarından oluşur. ḫaššumaš bayramı bazı özellikleri ile diğer Hitit bayram törenlerinden ayrılmaktadır. Dört gün süren bu bayramda, prens ve ona eşlik eden çeşitli görevlilerin katıldığı ziyafet sahneleri betimlenmektedir. Hitit bayram törenlerine kraliyet ailesinden katılanlar genellikle kral ve kraliçeler olmuştur. Prensler ise bayramlarda kral ve kraliçeye eşlik etmişler veya nadiren tek başlarına bayramları icra etmişlerdir. Ancak ḫaššumaš bayramında kraliçe adına hiç rastlamamakla beraber kral sözcüğü bir defa geçmektedir. Prensin bu bayramda baş karakter olduğu açıktır. Diğer taraftan birçok tanrıya kurbanların sunulması ve burada tüketilen yiyecek çeşitliliği ḫaššumaš bayramının dikkat çekici özelliklerindendir. Yine prensin farklı mekanlara gidip mutfaktan yemek istemesi sonrasında sürekli hazırlanan sofralar bir çeşit ziyafet yapıldığının göstergesidir. ḫaššumaš bayramına ait metnin elimizde olan nüshalarından bayramın hangi amaçla yapıldığını tam olarak bilmiyor olsak da yorumlamalara burada yer verilecektir. Çalışmamızın amacı ḫaššumaš bayram metninin transliterasyon ve Türkçe çevirisini yapıp metinde adı geçen sunuları filolojik yönden değerlendirmektir.
Does Gamifying in the Marketplace Help in Building Consumer Engagement and Intention to Buy Online?
Authors: Rizano Shantira Ayusha , Salehudin Imam
Published: September 2023

E-commerce is gaining consumer acceptance due to increased internet penetration and advancements in Indonesia. To engage tech-savvy consumers and meet their evolving needs, e-commerce players use gamification by offering personalized shopping experiences, social functionalities, and easy product access. This study examines how Shopee, an e-commerce retailer, can optimize its gamification strategies and intrinsic motivations to encourage customer engagement and impulsive buying behaviour. The study employs purposive sampling to survey 204 respondents and found that gamification and intrinsic motivations positively influence customer shopping engagement. The data was analyzed using Partial Least Squares (PLS) with the SmartPLS software. The findings show that gamification and intrinsic motivations hold a positive influence on shopping engagement. Furthermore, socialness and shopping enjoyment lead to increased impulsive buying behavior. Notably, shopping engagement emerges as a critical factor positively shaping users' intention to continue using online shopping applications.
The Mediating Effect of Religious Attitude on the Relationship Between Mindfulness and Covid-19 Fear
Authors: GÜLDAŞ Fatümetül Zehra
Published: September 2023

The worldwide Covid-19 pandemic, which has significantly affected the entire globe for the past three years, has also influenced daily life and mental well-being in various ways. Many studies have emphasized that the use of religion as a coping mechanism can be an effective factor in improving mental health. Therefore, this study examines the cross-sectional relationship between religious attitude, mindfulness, and Covid-19 fear besides the Covid-19 anxiety levels that individuals are exposed to and evaluates the mediating role of religiosity in this relationship. A survey of 440 participants with most were female (80.2%) and single (68.2%) were obtained online by random sampling. The demographic results indicated that women exhibited a higher level of Covid-19 fear compared to men, showing a significant difference. In religious attitude and mindfulness scores, there was no significant difference observed by gender. The correlational analysis demonstrated that a higher fear of Covid-19 was significantly linked to lower levels of mindfulness and religious attitude, but it did not show any significant association with religious coping. The mediational analysis indicated that religious attitude acts as a partial mediator in the association between trait mindfulness and fear of Covid-19, implying that the impact of mindfulness on fear of Covid-19 was explained by the influence of religious attitude. While limitations of the study design exist, the findings suggest that belief-based behaviors may play an active role in mental health management during crises, and strategies that promote religious attitudes and mindfulness during times of life crises requires further investigations.
Zu den Knotenpunkten der borromäischen Ringe Exklusion : Inklusion : Apersion. Praxeologische Lesarten als Analytik und Reflexion von Tiefenstrukturen sonderpädagogischer Konstellationen
Authors: Link Pierre-Carl
Published: September 2023

Die Praxeologie soll als hilfreiche Blickrichtung in der Allgemeinen Sonderpädagogik in diesem Beitrag kritisch reflektiert werden. Dabei wird der Frage nachgegangen, ob ein stärker praxeologischer Zugang zur disziplinären Selbstvergewisserung und Professionalisierung der Sonderpädagogik als Disziplin, Profession und Praxis verhilft. (DIPF/Orig.)
Jak wychowywać do wartości w przestrzeni przedszkolnej w społeczeństwie transkulturowym?
Authors: Lisowska Kinga , Leszczyńska-Rejchert Anna
Published: September 2023

W dobie dynamicznie zmieniającej się rzeczywistości należy przyjrzeć się wartościom przekazywanym najmłodszym pokoleniom oraz zrewidować dotychczasowe podstawy teoretyczne procesu edukacji już na etapie wychowania przedszkolnego. Problematyka ta jest niezwykle ważna z punktu widzenia pedagogicznego, gdyż dotyczy istoty wychowania. Celem podjętej analizy naukowej była próba nakreślenia sposobu wychowywania do wartości dzieci w państwowych placówkach przedszkolnych z uwzględnieniem perspektywy przygodności struktur kulturowych i ich hybrydyzacji. Podstawę analiz stanowiły dwie jakościowe metody zbierania danych, tj. analiza danych zastanych (podstawy programowej wychowania przedszkolnego) oraz wywiady indywidualne, częściowo kierowane, skoncentrowane na problemie z 50 rodzicami dzieci uczęszczających do przedszkoli państwowych na terenie Olsztyna. Badania zrealizowano w okresie kwiecień–czerwiec 2022 r. W artykule przedstawiono problematykę wartości fundamentalnych oraz wychowania do wartości w przestrzeni przedszkolnej. Skupiono się także na zagadnieniu transkulturowości w rozumieniu pedagogicznym. Analiza danych zastanych ujawniła potrzebę zmian w kierunku łączenia edukacji regionalnej i międzykulturowej w przestrzeni teoretycznej i praktycznej pracy przedszkoli – stanowią one podstawę transkulturowego procesu wychowywania do wartości. Wypowiedzi rodziców natomiast wskazują na potrzebę wprowadzania w życiu młodego człowieka wartości fundamentalnych, umożliwiających przejście do wartości rodzinnych, a następnie do wartości związanych z szacunkiem i tolerancją, ale także zdążających ku współistnieniu oraz swobodnemu korzystaniu z różnych elementów kulturowych.
Pluralizm w edukacji językowej – konceptualizacje, implikacje dydaktyczne
Authors: Krasuska-Betiuk Marta
Published: September 2023

Artykuł ma charakter metajęzykowej refleksji na temat potencjału dydaktycznego  plurilingwalizmu a jego celem jest prezentacja założeń koncepcyjnych wybranych pluralistycznych koncepcji edukacji językowej, które lingwiści określają mianem plurilingual pedagogies. To grupa podejść metodologiczno-teoretycznych i praktycznych, uznawanych nie tylko za innowacyjne, wartościowe i skuteczne ale też konieczne do zastosowania we współczesnej edukacji. I chociaż różnojęzyczność funkcjonuje w polskim systemie w placówkach dwujęzycznych i międzynarodowych, w formie koncepcji dydaktycznych, programów lub  rozwiązań metodycznych, autorka dostrzega potrzebę jej szerszego wykorzystania, implementację do codziennej praktyki szkolnej, w obecnych czasach , gdy każde dziecko jest w procesie dochodzenia do określonego poziomu dwujęzyczności a każdy nauczyciel jest nauczycielem języka. W artykule przedstawiono najważniejsze podejścia: prulilingualism, translanguanging i language awareness, które są stosowane w codziennej praktyce językowej rodzin i społeczności wielojęzycznych oraz mają zastosowanie w różnojęzycznych grupach, klasach, w pracy z  dziećmi z doświadczeniem migracji.