bluuebunny/crossref_metadata_2025 huggingface dataset:
Intergenerational Influence of Gender and the DM1 Phenotype of the Transmitting Parent in Korean Myotonic Dystrophy Type 1
Authors: Han Ji Yoon , Jang Woori , Park Joonhong
Published: August 2022

Myotonic dystrophy type 1 (DM1) is the most common autosomal-dominant disorder caused by the CTG repeat expansion of the DMPK, and it has been categorized into three phenotypes: mild, classic, and congenital DM1. Here, we reviewed the intergenerational influence of gender and phenotype of the transmitting parent on the occurrence of Korean DM1. A total of 44 parent–child pairs matched for the gender of the transmitting parent and the affected child and 29 parent–child pairs matched for the gender and DM1 phenotype of the transmitting parent were reviewed. The CTG repeat size of the DMPK in the affected child was found to be significantly greater when transmitted by a female parent to a female child (DM1-FF) (median, 1309 repeats; range, 400–2083) than when transmitted by a male parent to a male child (650; 160–1030; p = 0.038 and 0.048 using the Tukey HSD and the Bonferroni test) or by a male parent to a female child (480; 94–1140; p = 0.003). The difference in the CTG repeat size of the DMPK between the transmitting parent and the affected child was also lower when transmitted from a male parent with classic DM1 (−235; −280 to 0) compared to when it was transmitted from a female parent with mild DM1 (866; 612–905; p = 0.015 and 0.019) or from a female parent with classic DM1 (DM1-FC) (605; 10–1393; p = 0.005). This study highlights that gender and the DM1 phenotype of the transmitting parent had an impact on the CTG repeat size of the DMPK in the affected child, with greater increases being inherited from the DM1-FF or DM1-FC situations in Korean DM1.
Evolution of the Noncoding Features of Sea Snake Mitochondrial Genomes within Elapidae
Authors: Xiaokaiti Xiakena , Hashiguchi Yasuyuki , Ota Hidetoshi , Kumazawa Yoshinori
Published: August 2022

Mitochondrial genomes of four elapid snakes (three marine species [Emydocephalus ijimae, Hydrophis ornatus, and Hydrophis melanocephalus], and one terrestrial species [Sinomicrurus japonicus]) were completely sequenced by a combination of Sanger sequencing, next-generation sequencing and Nanopore sequencing. Nanopore sequencing was especially effective in accurately reading through long tandem repeats in these genomes. This led us to show that major noncoding regions in the mitochondrial genomes of those three sea snakes contain considerably long tandem duplications, unlike the mitochondrial genomes previously reported for same and other sea snake species. We also found a transposition of the light-strand replication origin within a tRNA gene cluster for the three sea snakes. This change can be explained by the Tandem Duplication—Random Loss model, which was further supported by remnant intervening sequences between tRNA genes. Mitochondrial genomes of true snakes (Alethinophidia) have been shown to contain duplicate major noncoding regions, each of which includes the control region necessary for regulating the heavy-strand replication and transcription from both strands. However, the control region completely disappeared from one of the two major noncoding regions for two Hydrophis sea snakes, posing evolutionary questions on the roles of duplicate control regions in snake mitochondrial genomes. The timing and molecular mechanisms for these changes are discussed based on the elapid phylogeny.
Epigenetic Alterations in Sports-Related Injuries
Authors: Tarnowski Maciej , Tomasiak Patrycja , Tkacz Marta , Zgutka Katarzyna , Piotrowska Katarzyna
Published: August 2022

It is a well-known fact that physical activity benefits people of all age groups. However, highly intensive training, maladaptation, improper equipment, and lack of sufficient rest lead to contusions and sports-related injuries. From the perspectives of sports professionals and those performing regular–amateur sports activities, it is important to maintain proper levels of training, without encountering frequent injuries. The bodily responses to physical stress and intensive physical activity are detected on many levels. Epigenetic modifications, including DNA methylation, histone protein methylation, acetylation, and miRNA expression occur in response to environmental changes and play fundamental roles in the regulation of cellular activities. In the current review, we summarise the available knowledge on epigenetic alterations present in tissues and organs (e.g., muscles, the brain, tendons, and bones) as a consequence of sports-related injuries. Epigenetic mechanism observations have the potential to become useful tools in sports medicine, as predictors of approaching pathophysiological alterations and injury biomarkers that have already taken place.
Quitting Smoking before and after Pregnancy: Study Methods and Baseline Data from a Prospective Cohort Study
Authors: Cruvinel Erica , Richter Kimber P. , Pollak Kathryn I. , Ellerbeck Edward , Nollen Nicole L. , Gajewski Byron , Sullivan-Blum Zoe , Zhang Chuanwu , Shergina Elena , Scheuermann Taneisha S.
Published: August 2022

Smoking during pregnancy and postpartum remains an important public health problem. No known prior study has prospectively examined mutual changes in risk factors and women’s smoking trajectory across pregnancy and postpartum. The objective of this study was to report methods used to implement a prospective cohort (Msgs4Moms), present participant baseline characteristics, and compare our sample characteristics to pregnant women from national birth record data. The cohort study was designed to investigate smoking patterns, variables related to tobacco use and abstinence, and tobacco treatment quality across pregnancy through 1-year postpartum. Current smokers or recent quitters were recruited from obstetrics clinics. Analyses included Chi-square and independent sample t-tests using Cohen’s d. A total of 62 participants (41 smokers and 21 quitters) were enrolled. Participants were Black (45.2%), White (35.5%), and multiracial (19.3%); 46.8% had post-secondary education; and most were Medicaid-insured (64.5%). Compared with quitters, fewer smokers were employed (65.9 vs 90.5%, Cohen’s d = 0.88) and more reported financial strain (61.1% vs 28.6%; Cohen’s d = 0.75). Women who continue to smoke during pregnancy cope with multiple social determinants of health. Longitudinal data from this cohort provide intensive data to identify treatment gaps, critical time points, and potential psychosocial variables warranting intervention.
Changes in Canadian Adolescent Well-Being since the COVID-19 Pandemic: The Role of Prior Child Maltreatment
Authors: Dion Jacinthe , Hamel Catherine , Clermont Camille , Blackburn Marie-Ève , Hébert Martine , Paquette Linda , Lalande Daniel , Bergeron Sophie
Published: August 2022

Adolescents may be particularly vulnerable to the negative impact of the coronavirus disease 2019 (COVID-19) pandemic, given their increased socialization needs during this developmental period. This prospective study examined the potential changes in adolescents’ well-being from before to during the pandemic, and the moderating role of a history of child maltreatment (CM), COVID-19-related distress, and gender among 1,802 adolescents (55.5% participants identified as boy, 42.2% as girl, and 1.5% as nonbinary; Mage 14.74 years). Another aim was to determine whether COVID-19-related distress mediated the relationship between CM and well-being. Results revealed that COVID-19-related distress was associated with lower well-being (i.e., higher levels of internalized and externalized behaviors, and lower levels of self-esteem and life satisfaction). Boys experienced a greater decrease in life satisfaction and self-esteem than girls. A history of CM had a moderation effect, with the pandemic having a lesser impact on the outcomes of adolescents with such a history. However, it was also associated with more COVID-19-related distress, which in turn was associated with lower levels of internalized and externalized behaviors, self-esteem, and life satisfaction. These unexpected results with regard to CM might indicate that the social restrictions during the pandemic could have had a relieving effect on adolescents with particular challenges associated with CM.
The Spanish Version of the State Self-Compassion Scale–Long Form (SSCS–L): A Study of Its Validity and Reliability in a Sample of Nursing Students
Authors: Galiana Laura , Guillén Mireia , Pades Antonia , Flowers Sarah L. , Vidal-Blanco Gabriel , Sansó Noemí
Published: August 2022

Background: In nurses, self-compassion mitigates the effects of stress, burnout and compassion fatigue, and enhances empathy, compassion and well-being and quality of life. The Self-Compassion Scale is the most-used instrument. The aim of this study is to validate the Spanish version of the new developed State Self-Compassion Scale–Long (SSCS–L). Methods: Students of the first year of the Nursing Degree were surveyed online. Together with the SSCS–L, their levels of positive and negative affect was reported. Analyses included descriptive statistics, competitive confirmatory factor analysis, evidence on criterion-related validity and estimates of reliability. Results: The best fitting model for the SSCS–L was the one hypothesizing six-correlated factors of self-compassion: self-kindness, common humanity, mindfulness, self-judgement, isolation, and over-identification. Positive relations between the positive dimensions of self-compassion and positive affect were found, whereas there were negative relations between the positive poles of self-compassion and negative affect. Estimates of reliability were adequate, except for the dimension of over-identification. Conclusions: Self-compassion has become a key competency for nurses. The SSCS–L is an appropriate tool to allow an adequate assessment of self-compassion in experimental contexts.
Knowledge, Behaviour and Attitudes Related to Sun Exposure in Sportspeople: A Systematic Review
Authors: Fernandez-Ruiz Jonatan , Montero-Vilchez Trinidad , Buendia-Eisman Agustin , Arias-Santiago Salvador
Published: August 2022

People who practice outdoor sports have an increased risk of skin cancer as they are exposed to high doses of ultraviolet (UV) radiation. Recent studies have shown that in many athletes, sun protection behaviours are inadequate, with the risk that this entails. The aim of this review is to collect the information published to date about the knowledge, attitudes and habits of athletes in relation to sun exposure and its risks. A systematic review was conducted using PubMed and Embase with the search algorithm “(skin cancer OR melanoma) AND (exercise OR sport OR athletes)”. All studies analysing the knowledge, attitudes and habits of photoprotection in athletes were included. A total of 2,365 publications were found, of which 23 were selected, including a total of 10,445 sportspeople. The majority of participants declared their voluntary intention to tan and stated that the sun made them feel better, although they also showed concern about possible damage associated with UV radiation. In most studies, less than half of the participants made adequate use of photoprotective measures. In general, most athletes had a high level of knowledge regarding the risk of skin cancer associated with sun exposure. In conclusion, most athletes are aware of the risks associated with UV radiation but do not make adequate use of photoprotective cream. New training programs on photoprotection could help improve athletes’ photoprotective behaviour, reducing the incidence of skin cancer and precancerous lesions in this population.
The Mediating Role of Loneliness and the Moderating Role of Gender between Peer Phubbing and Adolescent Mobile Social Media Addiction
Authors: Xu Xiao-Pan , Liu Qing-Qi , Li Zhen-Hua , Yang Wen-Xian
Published: August 2022

Mobile social media addiction has been a pressing issue in adolescents. The present study examined the mediation of loneliness between peer phubbing and mobile social media addiction among Chinese adolescents and tested whether gender could moderate the direct and indirect effects of peer phubbing. A total of 830 adolescents between 11 and 18 years of age (Mage = 14.480, SDage = 1.789) completed an anonymous self-report survey. The results showed that peer phubbing was positively associated with mobile social media addiction. Loneliness partially mediated peer phubbing and adolescent mobile social media addiction. There were significant gender differences in the direct and indirect effects of peer phubbing on mobile social media addiction. The direct effect of peer phubbing and the indirect effect through loneliness were relatively higher in girls than in boys. The results highlight the critical role of loneliness in linking peer phubbing to adolescent mobile social media addiction and the vital role of gender in moderating the direct and indirect impacts of peer phubbing. The findings promote a better understanding of how peer phubbing is associated with adolescent mobile phone addiction and for whom the effect of peer phubbing is potent.
The Effectiveness of Interventions to Reduce Sedentary Time in Different Target Groups and Settings in Germany: Systematic Review, Meta-Analysis and Recommendations on Interventions
Authors: Mugler Nida , Baurecht Hansjörg , Lam Kevin , Leitzmann Michael , Jochem Carmen
Published: August 2022

Background: Sedentary behavior is an important risk factor for several chronic diseases and is associated with an increased risk of mortality. We assessed the effectiveness of interventions to reduce sedentary time in Germany and provide recommendations on interventions to reduce sedentary time in children and adults. Methods: We comprehensively searched PubMed, Web of Science and the German Clinical Trials Register up to April 2022 for intervention studies targeting sedentary behavior in Germany. We performed a systematic review and qualitative synthesis of the interventions and a meta-analysis in children. Results: We included 15 studies comprising data from 4588 participants. The results of included primary studies in adults and children showed inconsistent evidence regarding change in sedentary time, with a majority of studies reporting non-significant intervention effects. The meta-analysis in children showed an increase in sedentary time for children in the control and intervention groups. Conclusion: We found inconsistent evidence regarding the effectiveness of interventions to reduce time spent sedentary and our meta-analysis showed an increase in sedentary time in children. For children, we recommend physical and social environment interventions with an active involvement of families. For adults, we recommend physical environment interventions, such as height-adjustable desks at work.
Development of Narratives and Belief in a Just World in Victims of Bullying Due to Sexual and Gender Diversity Issues
Authors: Sibony Adrián , Jacott Liliana
Published: August 2022

Students belonging to a sexual and gender minority go through experiences of injustice in their educational centers and are victims of school bullying. This research analyzes the relationship between these experiences and their influence on the development of the Belief in a Just World, as well as the impact of their experiences on the development of their narratives. Participants are students who have suffered from bullying due to sexual and gender diversity issues during their primary and secondary education stages (ages 15–40 years). Starting from a constructivist qualitative methodological approach, a semi-structured interview was developed as an instrument for collecting data on these aspects. The information extracted was contrasted with the results of the Personal and General Belief in a Just Word Scales. The results of the first interviews provide us with prior information on current identities and narratives and their representations of justice.
A Study on the Path to the Sustainable Development of Sports-Consuming Cities—A Qualitative Comparative Analysis of Fuzzy Sets Based on Data from 35 Cities in China
Authors: Li Xinze , Yu Ronghui , Yan Chenjie , Xie Hongwei
Published: August 2022

The prospects of China’s sports sector hinge on how sports cities can thrive sustainably in the context of the new global pandemic, unlocking consumer potential and boosting domestic demand. In this study, 35 Chinese cities were chosen as research samples, and research methods such as literature, logical analysis, and fuzzy-set qualitative comparative analysis were used to select conditional variables such as government policy promotion and assistance, expert human resources, sports competitions and events, stadiums and facilities, and sponsorship by sports enterprises to examine how Chinese sports-consuming cities can develop sustainably. The research discovered that sports contests and events, as well as stadiums and facilities, are the essential prerequisites for the sustainable growth of sports-consuming cities, and that diverse combinations of the two may play a vital role in different circumstances. For the sustainable development of sports-consuming cities, there are four clusters and three models, which correspond to the “Venue + Event” model (Clusters 1 and 2), the “Event-led” model (Cluster 3), and the “Venue-led” model (Cluster 4). To encourage the high-quality growth of China’s sports business, each city may establish its development strategy based on its unique qualities. The goal is to supply Chinese expertise for the long-term growth of Western sports cities.
Nutrition and Food Literacy in the MENA Region: A Review to Inform Nutrition Research and Policy Makers
Authors: Mohsen Hala , Sacre Yonna , Hanna-Wakim Lara , Hoteit Maha
Published: August 2022

Background: Improving food and nutrition literacy is fundamental to tackling the Middle East and North Africa (MENA) region’s enormous challenges, including malnutrition and food insecurity. To direct initiatives, it is crucial to assess the region’s food and nutrition literacy. Thus, we aimed to review studies on food/nutrition literacy status in the MENA countries and illuminate the region’s research gaps in these areas, in terms of assessment, policy, and program implementation. Methods: PubMed and Google Scholar databases were searched between 18 December and 8 May 2022, to identify relevant articles published up to 2022 in the MENA region. Results: Twelve studies were included in this review. Lebanon, Palestine, and Iran are the only three MENA countries where nutrition and/or food literacy were assessed. People in these countries mostly had inadequate food and/or nutrition literacy levels, especially in the skills rather than the cognitive domain. Food and/or nutrition literacy showed associations with food habits, food-label use, food-consumption patterns, school performance, food security, dietary diversity, and nutrient adequacy. The MENA countries developed no policies or programs to address food and nutrition literacy. Conclusion: This review is a wake-up call for researchers and policymakers to develop a robust approach to combat food and nutrition literacy concerns in the MENA region.
Effects of Simulated Laughter Therapy Using a Breathing Exercise: A Study on Hospitalized Pulmonary Tuberculosis Patients
Authors: Jang Kwang-Sim , Oh Jeong-Eun , Jeon Gyeong-Suk
Published: August 2022

This study evaluated the effects of simulated laughter therapy on physical symptoms, pulmonary function, depression, and health-related quality of life (HRQOL) among pulmonary tuberculosis patients. This quasi-experimental study assigned tuberculosis patients of hospital A to a laughter group (n = 26) and those of hospital B to a control group (n = 26). The eight-week laughter therapy, held twice a week in a 60-min group session, included laughter, entertainment, music-related chorusing, breathing exercises, and meditation. The values of physical symptoms, pulmonary function, depression, and HRQOL from before and after the therapy were analyzed using the paired t-test and the Mann–Whitney U-test. To verify group differences between the experiment and control group, the Wilcoxon signed-rank test and the analysis of covariance (ANCOVA) were employed. Unlike the control group, laughter therapy decreased physical symptoms (t = 7.30, p < 0.01) and increased pulmonary function (t = −3.77, p < 0.01). Psychological health also improved, including depression (t = 10.46, p < 0.01) and HRQOL (t = −9.31, p < 0.01) in the experimental group but not in the control group. Group differences of changes in physical symptoms, pulmonary function, depression, and HRQOL were also significant. Simulated laughter therapy can help moderate depression and physical symptoms and enhance pulmonary function among tuberculosis patients.
The Effect of Binaural Beat Audio on Operative Pain and Anxiety in Cataract Surgery under Topical Anaesthesia: A Randomized Controlled Trial
Authors: Loong Ling Jiunn , Ling Koh Koon , Tai Evelyn Li Min , Kueh Yee Cheng , Kuan Garry , Hussein Adil
Published: August 2022

Background: The aim of this paper was to examine the analgesic and anxiolytic effects of binaural beat audio in patients undergoing cataract surgery under topical anaesthesia. Methods: This was a prospective, randomized controlled trial of 61 patients undergoing cataract surgery under topical anaesthesia. They were divided into two research conditions; the binaural beat audio group, and a sham-control group (ear phones with no music). Patients completed the State-Trait Anxiety Inventory questionnaire (STAI), and their blood pressure (BP) and heart rate (HR) were measured pre- and post-intervention. Intraoperative pain levels were ascertained using a visual analog scale (VAS) completed immediately after the surgery. Results: The binaural beat group had significantly lower pain scores (p < 0.001), HR (p < 0.001), diastolic BP (p = 0.003), mean arterial pressure (p = 0.007) and anxiety (p = 0.009) than the control group. Within the binaural beat group, subjects experienced a statistically significant reduction in HR (p = 0.004) and anxiety (p < 0.001) levels compared to baseline values, while all parameters, except anxiety, increased significantly in the control group. Conclusions: Binaural beat audio decreases operative pain and anxiety in cataract surgery under topical anaesthesia. It may have additional benefits in modulating the tachycardic response to stress.
The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
Authors: Carriedo-Diez Bárbara , Tosoratto-Venturi Javier Lucas , Cantón-Manzano Carmen , Wanden-Berghe Carmina , Sanz-Valero Javier
Published: August 2022

(1) Background: To know the medical documentation related to exogenous melatonin in sleep disorders caused by shift work in health personnel; (2) Methods: Systematic and critical review. Data were obtained by looking up the bibliographic data base: MEDLINE (via Pubmed), Embase, Cochrane Library, Scopus, Web of Science, Latin American and Caribbean literature in Health Sciences (LILACS) and Medicine in Spanish (MEDES). The used terms, as descriptors and text in the title and abstract record fields, were “Health Personnel”, “Melatonin” and “Sleep Disorders”, Circadian Rhythm, by using the following filters: “Humans”, “Adult: 19+ years” and “Clinical Trial”. The search update was in December 2021. The documentary quality of the articles was assessed using the CONSORT questionnaire. (3) Results: Having applied the inclusion and exclusion criteria, 10 clinical essays were selected out of 98 retrieved references. CONSORT scores ranged from a minimum of 6.0 to a maximum of 13. 7 with a median of 10.2. According to the SIGN criteria, this review presented “1-“evidence with a grade of recommendation B. The intervention dose via administration of exogenous melatonin ranged between 1 and 10 mg. It was not mentioned whether the route of administration was by fast or slow absorption. The outcomes showed decreased daytime sleepiness, lessened sleep onset latency, diminished night-time awakenings, increased total sleep period and improved daytime attention in the melatonin-treated group; (4) Conclusions: Exogenously administered melatonin is effective in shift worker health personnel that are suffering from sleep disorders, and given its low adverse effects and tolerability, it might be recommended. A great disparity was evidenced in terms of dose, follow-up periods and type of melatonin, small participant population, same age ranges and young age. Therefore, new trials would be needed to amend these observations in order to have full evidence that is able to ensure the efficacy of exogenous melatonin in the studied population.
Evaluation and Obstacle Analysis of Emergency Response Capability in China
Authors: Wang Huiquan , Ye Hong , Liu Lu , Li Jixia
Published: August 2022

Emergency response capability evaluation is an essential means to strengthen emergency response capacity-building and improve the level of government administration. Based on the whole life cycle of emergency management, the emergency capability evaluation index system is constructed from four aspects: prevention and emergency preparedness, monitoring and early warning, emergency response and rescue, and recovery and reconstruction. Firstly, the entropy method is applied to measure the emergency response capability level of 31 Chinese provinces from 2011 to 2020. Second, the Theil index and ESDA (Exploratory Spatial Data Analysis) are applied in exploring the regional differences and spatial-temporal distribution characteristics of China’s emergency response capacity. Finally, the obstacle degree model is used to explore the obstacle factors and obstacle degrees that affect the emergency response capability. The results show that: (1) The average value of China’s emergency response capacity is 0.277, with a steady growth trend and a gradient distribution of “high in the east, low in the west, and average in center and northeast” in the four major regions. (2) From the perspective of spatial distribution characteristics, the unbalanced regional development leads to the obvious aggregation effect of “high-efficiency aggregation and low-efficiency aggregation”, and the interaction of the “centripetal effect” and “centrifugal effect” finally forms the spatial clustering result of emergency response capability level in China. (3) Examining the source of regional differences, inter-regional differences are the decisive factor affecting the overall differences in emergency response capability, and the inter-regional differences show a reciprocating fluctuation of narrowing–widening–narrowing from 2011 to 2020. (4) Main obstacles restricting the improvement of China’s emergency response capabilities are “the business volume of postal and telecommunication services per capita”, “the daily disposal capacity of city sewage” and “the general public budget revenue by region”. The extent of the obstacles’ impacts in 2020 are 12.19%, 7.48%, and 7.08%, respectively. Based on the evaluation results, the following countermeasures are proposed: to realize the balance of each stage of emergency management during the holistic process; to strengthen emergency coordination and balanced regional development; and to implement precise measures to make up for the shortcomings of emergency response capabilities.
Prevalence and Factors Associated with Metabolic Syndrome in Patients at a Psychosocial Care Center: A Cross-Sectional Study
Authors: Reis da Silva Dandara Almeida , de Almeida Ludmila Santana , Correa Livia Lugarinho , Pimentel Rodrigo Fernandes Weyll , Gomes Antonio Marcos Tosoli , Travassos Ana Gabriela , Viana Adriana Mattos , Cerqueira Monique Magnavita Borba da Fonseca , de Souza Marcio Costa , de Sousa Anderson Reis , Barbosa Paulo José Bastos , Coelho Julita Maria Freitas , Magalhães Lucelia Batista Neves Cunha , D’Oliveira Júnior Argemiro , Cavalcante Neto Jorge Lopes , Santos Charles Souza , França Luiz Carlos Moraes , Brandão Juliana de Lima , dos Santos Livia Fajin de Mello , Gomes Helena Ferraz , Peres Ellen Marcia , Rossi Thais Regis Aranha , Damasceno Kairo Silvestre Meneses , das Mercês Millena Conceição , Fernandes Sandra Lúcia , Soriano Eline de Almeida , Maduro Isolda Prado de Negreiros Nogueira , Brandão Tatiana Santos , Menezes Amanda Cardoso , Santana Amália Ivine Costa , das Merces Magno Conceição
Published: August 2022

Background: Metabolic syndrome (MS) is associated with greater risk of morbimortality and it has high prevalence in people with mental illness. Objective: Estimate the prevalence of Metabolic Syndrome (MS) and its associated factors in the patients of a Psychosocial Care Center (CAPS in Brazilian Portuguese) in the city of Salvador, state of Bahia, Brazil. Method: Cross-sectional study set at CAPS in the city of Salvador-Bahia between August 2019 and February 2020. MS was evaluated according to the National Cholesterol Education Program’s Adult Treatment Panel III. In addition to descriptive statistics, gross and adjusted prevalence ratios were described. Results: MS was found in 100 (35.2%) individuals, 116 (40.9%) were obese and 165 (58.1%) had increased waist circumference. Polypharmacy was identified in 63 (22.3%) patients and 243 (85.9%) used antipsychotics. Under gross evaluation, women (PR = 1.88; 95%CI: 1.35–2.63) and those who used antidepressants (PR = 1.41; 95%CI: 1.05–1.88) showed an association with MS. After logistic regression, depression (PR = 1.86; 95%CI: 1.38–2.51), acanthosis (PR = 1.50; 95%CI: 1.18–1.90), use of antipsychotics (PR = 1.88; 95%CI: 1.13–2.75), and hypertriglyceridemic waist (PR = 3.33; 95%CI: 2.48–4.46) were associated with MS. Conclusion: The prevalence of MS signals multimorbidity among individuals with mental disorders and suggests a need for clinical screening.
The Spatial and Temporal Evolution of the Coordination Degree in Regard to Farmland Transfer and Cultivated Land Green Utilization Efficiency in China
Authors: Zhou Min , Kuang Bing , Zhou Min , Ke Nan
Published: August 2022

In many parts of the world, the shortage of cultivated land and the food crisis are worsening on a continued basis. Hence, the central and local governments of the PRC have successively issued various related policies to encourage the practice of farmland transfer, promote the eco-friendly utilization of cultivated land, and ameliorate the efficiency of cultivated land utilization. Under the context of large-scale farmland transfer and rural revitalization strategy in China, it is significant to ensure agricultural sustainability through the coordination of farmland transfer and the amelioration of cultivated land green utilization efficiency (CLGUE). In the present study, 30 Chinese provinces were taken as the research object, with the super-efficient SBM model, the coupling coordination degree model and the spatial analysis model applied in combination. Based on the measurement of CLGUE, a thorough analysis was conducted to explore the evolution of coordination degree in regard to farmland transfer and CLGUE in China from both spatial and temporal perspectives. The conclusions drawn from this study are as follows. Firstly, the overall CLGUE exhibited an upward tendency in the PRC, from 0.440 in 2005 to 0.913 in 2019, with a yearly growth rate of 5.47% on average. However, there were significant spatial disparities in CLGUE between different regions and provinces. Secondly, there was a steady increasing trend shown by the level of coordination degree regarding farmland transfer and CLGUE across China. Further, due to the variation in natural and economic conditions, there were significant spatial–temporal disparities in the coordination degree among these 30 provinces. Lastly, there were obvious spatial aggregation patterns at the provincial level regarding the coordination degree in farmland transfer and CLGUE across China. However, there was a declining trend in the level of spatial aggregation patterns for coordination degree.
Cohen’s Kappa Coefficient as a Measure to Assess Classification Improvement following the Addition of a New Marker to a Regression Model
Authors: Więckowska Barbara , Kubiak Katarzyna B. , Jóźwiak Paulina , Moryson Wacław , Stawińska-Witoszyńska Barbara
Published: August 2022

The need to search for new measures describing the classification of a logistic regression model stems from the difficulty in searching for previously unknown factors that predict the occurrence of a disease. A classification quality assessment can be performed by testing the change in the area under the receiver operating characteristic curve (AUC). Another approach is to use the Net Reclassification Improvement (NRI), which is based on a comparison between the predicted risk, determined on the basis of the basic model, and the predicted risk that comes from the model enriched with an additional factor. In this paper, we draw attention to Cohen’s Kappa coefficient, which examines the actual agreement in the correction of a random agreement. We proposed to extend this coefficient so that it may be used to detect the quality of a logistic regression model reclassification. The results provided by Kappa‘s reclassification were compared with the results obtained using NRI. The random variables’ distribution attached to the model on the classification change, measured by NRI, Kappa, and AUC, was presented. A simulation study was conducted on the basis of a cohort containing 3971 Poles obtained during the implementation of a lower limb atherosclerosis prevention program.
Adherence to eHealth-Delivered Exercise in Adults with no Specific Health Conditions: A Scoping Review on a Conceptual Challenge
Authors: Fuente-Vidal Andrea , Guerra-Balic Myriam , Roda-Noguera Oriol , Jerez-Roig Javier , Montane Joel
Published: August 2022

Adherence has emerged as a focal point and critical determinant of success for physical activity interventions. The term is used for both traditional and digital interventions, and for prescribed and nonprescribed activities. Many other terms for adherence are being used interchangeably, as there is no consensus on its precise conceptualization. This scoping review aimed to advance the definition of adherence to eHealth programs, specifically for the adult population with no specific health conditions. A total of 2983 papers, published between 1 January 2016 and 13 March 2022, were retrieved from different databases (including grey literature). Of those, 13 studies met the eligibility criteria and were included for review. The selected studies used a wide array of technologies and consisted mainly of exercise interventions. Most of the reviewed publications contemplated exercise adherence as a percentage of expected dose. Most (8 out of 13) studies neither assessed nor specified an expected use of the involved technology. Results suggest a need for homogeneity in the conceptualization of adherence to physical activity and exercise, including those interventions delivered digitally.
The Influence of Family Caregiver Knowledge and Behavior on Elderly Diabetic Patients’ Quality of Life in Northern Thailand
Authors: Thongduang Kitbordin , Boonchieng Waraporn , Chautrakarn Sineenart , Ong-Artborirak Parichat
Published: August 2022

The quality of life (QoL) of elderly diabetic patients may be affected by caregiver factors, but this has received little empirical support. The objective of this cross-sectional study is to determine the influence of family caregivers’ diabetes knowledge and behavior on the QoL among elderly patients with diabetes mellitus (DM). The participants included 354 elderly patients with Type 2 DM and their family caregivers, who were recruited through multistage sampling from five districts in Chiang Mai, Thailand. Face-to-face interviews with DM patients were conducted using the Thai Simplified Diabetes Knowledge Scale (T-SDKS), the Thai version of the Diabetes Self-Management Questionnaire (DSMQ) for self-care behaviors, and the Thai version of the World Health Organization Quality of Life for Older People (WHOQOL-OLD) scale. For caregivers, their diabetes knowledge was measured by T-SDKS and patient-care or supportive behaviors were developed based on DSMQ. The results showed a moderate level of QoL among elderly diabetic patients. According to simple linear regression analysis, the QoL score among elderly DM patients was positively associated with their diabetes knowledge (B = 1.25), self-care behaviors (B = 3.00), caregivers’ knowledge (B = 0.97), and supportive behavior from caregivers (B = 2.92) at a significance level of p < 0.01. In the multivariable model, patients’ self-care behaviors (B = 1.58, p = 0.001), caregivers’ knowledge (B = 0.58, p = 0.001), and patient-care behaviors (B = 1.38, p = 0.004) were significantly associated with QoL among DM patients when controlling for patient factors, including age, body mass index (BMI), education, and living arrangements, which accounted for 27.0% of the variance. This indicates that caregivers’ adequate diabetes knowledge and appropriate supportive behaviors may impact the QoL of elderly diabetic patients. Health care providers should prioritize motivating and empowering family caregivers to pay more attention to the patient for the success goal.
The Effects of Standing Working Posture on Operation Force and Upper Limb Muscle Activation When Using Different Pointing Devices
Authors: Choi Jeewon , Lin Yu , Loh Ping Yeap
Published: August 2022

This study investigated how sitting and standing working postures affected operation force, upper limb muscle activation, and task performance using different pointing devices. Fifteen male participants completed cursor aiming and dragging tasks using a conventional mouse, a vertical mouse, and a trackball at sitting and standing workstations. A custom-made force plate was used to measure operation forces applied to the pointing devices. Surface electromyography (EMG) was used to capture the activation of the biceps brachii, triceps brachii, deltoid, and trapezius. Task performance was measured by task success rates, and subjective ratings were obtained for the force required for operation, smoothness of operation, accuracy, and local fatigue in the upper limb. We quantified the following significant outcomes: (1) greater operation forces were found when standing; (2) standing reduced EMG amplitudes of the triceps and trapezius muscles for all tasks; (3) during the aiming task, the vertical mouse had greater operation forces; (4) during the dragging task, both the vertical mouse and trackball had greater operation forces; and (5) task success rates differed for pointing devices only when sitting. This study revealed the distinct biomechanical properties of standing working posture and suggested limited beneficial effects of alternative pointing devices in terms of task performance and subjective ratings.
Humic Acids Affect the Detection of Metal Ions by Cyanobacteria Carbon Quantum Dots Differently
Authors: Liu Simin , Shi Yishen , Li Xiaona , Wang Zhenyu
Published: August 2022

A “top-down” synthesis of carbon quantum dots (CQDs), novel fluorescent C materials from waste biomass, is both cost-effective and environmentally friendly. N-rich cyanobacteria are promising precursors to produce CQDs with high fluorescence (FL) intensity for the detection of metal ions. Herein, we synthesized cyanobacteria-based CQDs using a hydrothermal process and evidenced their high FL intensity and stability. The cyanobacteria-based CQDs showed powerful sensitivity for the specific detection of Fe3+ and Cr6+, which could be ascribed to (i) static FL quenching as a result of the interaction between –OH, –NH2, and –COOH groups with the metal ions, (ii) internal filtering effects between the CQDs and Fe3+ or Cr6+, and (iii) fluorescence resonance energy transfer between CQDs and Cr6+. Humic acids (HAs) coexisting led to an underestimation of Fe3+ but an overestimation of Cr6+ by the CQDs due to the different FL quenching mechanisms of the CQDs. HAs sorbed Fe3+ and wrapped the CQDs to form a barrier between them, inhibiting FL quenching of CQDs by Fe3+. As for Cr6+, HAs reduced Cr6+ and also led to FL quenching; the sorbed HAs on the CQDs acted as a carrier of electrons between Cr6+ and the CQDs, enhancing FL quenching of the CQDs. This study is the first work to evidence the interference of HAs in the detection of metal ions by CQDs derived from cyanobacteria, which would enlighten the application of CQDs in a natural aqueous environment.
Revealing Impacts of Human Activities and Natural Factors on Dynamic Changes of Relationships among Ecosystem Services: A Case Study in the Huang-Huai-Hai Plain, China
Authors: Deng Longyun , Li Yi , Cao Zhi , Hao Ruifang , Wang Zheye , Zou Junxiao , Wu Quanyuan , Qiao Jianmin
Published: August 2022

Understanding the dynamic changes of relationships between ecosystem services (ESs) and their dominant factors can effectively adjust human activities to adapt proactively to global climate change. In this study, the Huang-Huai-Hai Plain (HHHP) was selected to assess the dynamics of four key ESs (NPP, net primary productivity; WY, water yield; SC, soil conservation; FP, food production) from 2000 to 2020. The constraint lines of interactions among ESs were extracted based on a segmented quantile regression model. On this basis, the effects of both human activities and natural factors on the key features of the interactions between ESs were quantified with the help of automatic linear model. The results indicated that two types of constraint relationships, including exponential and humped-shaped, existed among the six pairs of ESs. In the past two decades, small changes in NPP thresholds would lead to large variations in other ESs thresholds. Precipitation and normalized difference vegetation index were the key factors to determine the constraint strength of ESs in the HHHP. The potential maximum value of WY in the HHHP could be increased by adjusting landscape shape to make it more complicated. This study helps to improve the potential of target ESs and provides a decision-making basis for promoting regional sustainable development.
How Can Apartment-Complex Landscaping Space Improve Residents’ Psychological Well-Being?: The Case of the Capital Region in South Korea
Authors: Tae Jongwook , Jeong Daeyoung , Chon Jinhyung
Published: August 2022

Urban green spaces have a positive impact on citizens’ mental health and have contributed to improving their quality of life during the COVID-19 pandemic. In South Korea, where more than 50% of all households live in apartments, apartment-complex landscaping space plays the role of urban green space. This study aimed to investigate the relationships among a perceived restorative environment, restorative experience, life satisfaction, and psychological well-being by conducting a survey between residents living in apartments with landscape space. More specifically, an online survey was conducted from 8 to 15 June 2021 among residents in apartment complexes (500 households or more) located in the capital region in South Korea. We applied partial least squares structural equation modelling (PLS-SEM) using 220 samples to test the causal relationship presented in the conceptual model of this study. The results revealed that residents’ perceptions of the restorative environment of landscape space, including fascination, being away, and coherence had positive effects on restorative attention. Among the restorative environmental factors, the higher the “being away”, the greater the effect on restorative attention. Second, the effects of fascination and coherence on life satisfaction were mediated by restorative attention. Third, restorative attention and life satisfaction significantly influenced psychological well-being. Additionally, life satisfaction acts as a mediator in the relationship between restorative attention and psychological well-being. In summary, this study has theoretical implications, in that it explores the effects of apartment complex landscaping space as urban green spaces on residents’ mental health.
What Cause Large Spatiotemporal Differences in Carbon Intensity of Energy-Intensive Industries in China? Evidence from Provincial Data during 2000–2019
Authors: Xu Xin , Shen Yuming , Liu Hanchu
Published: August 2022

China has been reported as the world’s largest carbon emitter, facing a tough challenge to meet its carbon peaking goal by 2030. Reducing the carbon intensity of energy-intensive industries (EIICI) is a significant starting point for China to achieve its emission reduction targets. To decompose the overall target into regions, understanding the spatiotemporal differences and drivers of carbon intensity is a solid basis for the scientific formulation of differentiated regional emission reduction policies. In this study, the spatiotemporal differences of EIICI are described using the panel data of 30 provinces in China from 2000 to 2019, and a spatial econometric model is further adopted to analyze its drivers. As indicated by the results: (1) from 2000 to 2019, China’s EIICI tended to be reduced continuously, and the spatial differences at the provincial and regional levels expanded continuously, thus revealing the coexistence of “high in the west and low in the east” and “high in the north and low in the south” spatial patterns. (2) There is a significant spatial autocorrelation in the EIICI, characterized by high and high agglomeration and low and low agglomeration types. Moreover, the spatial spillover effects are denoted by a 1% change in the local EIICI, and the adjacent areas will change by 0.484% in the same direction. (3) Technological innovation, energy structure, and industrial agglomeration have direct and indirect effects, thus affecting the local EIICI and the adjacent areas through spatial spillover effects. Economic levels and firm sizes only negatively affect the local EIICI. Environmental regulation merely has a positive effect on adjacent areas. However, the effect of urbanization level on EIICI has not been verified, and the effect of urbanization level on the EIICI has not been verified. The results presented in this study show a scientific insight into the reduction of EIICI in China. Furthermore, policymakers should formulate differentiated abatement policies based on dominant drivers, spatial effects, and regional differences, instead of implementing similar policies in all provinces.
Temperature Asymmetry Analysis between Left and Right Wrist with Sensory and Infrared Thermography
Authors: García Becerra Alejandra , Olguín Tiznado Jesús Everardo , García Alcaraz Jorge Luis , Camargo Wilson Claudia , López Barreras Juan Andrés , Cano Gutiérrez Julio Cesar , Garcia-Rivera Rosa Blanca
Published: August 2022

This article reports a thermal analysis of the wrists to analyze the behavior and recovery of skin temperature after 20 min when performing a highly repetitive movement, and two thermography methods (sensory and infrared) and research groups were compared. The tests were carried out with 44 participants who performed a repetitive task for 10 min and integrated into two groups, of which 22 were trained workers from a maquiladora company and were analyzed with sensory thermography, and the other 22 were in the laboratory with infrared thermography with undergraduate students. The study area is the left and right hand, specifically the wrists. The proposed hypothesis is that people with some musculoskeletal problems have a decrease in temperature when starting repetitive tasks and thermal asymmetries, which measurements were recorded at 0, 10, 15, and 20 min after the task was finished. Findings indicate that the temperatures in both wrists behave similarly. The workers reached higher temperatures, and the centigrade degrees of asymmetry difference were also higher. The variable with influence on the temperature was fractured in the arm. After thermally analyzing the temperature behavior between the wrists of both hands, it is concluded that there is an increase in temperature after finishing a repetitive task, and it does not stabilize after 20 min. Both thermography methods observed that the asymmetries are greater than 0.5 °C, detecting the possible pathology of carpal tunnel syndrome.