bluuebunny/crossref_metadata_2025 huggingface dataset:
A further study on ordered regular equivalence relations in ordered semihypergroups
Authors: Tang Jian , Feng Xinyang , Davvaz Bijan , Xie Xiang-Yun
Published: March 2018

In this paper, we study the ordered regular equivalence relations on ordered semihypergroups in detail. To begin with, we introduce the concept of weak pseudoorders on an ordered semihypergroup, and investigate several related properties. In particular, we construct an ordered regular equivalence relation on an ordered semihypergroup by a weak pseudoorder. As an application of the above result, we completely solve the open problem on ordered semihypergroups introduced in [B. Davvaz, P. Corsini and T. Changphas, Relationship between ordered semihypergroups and ordered semigroups by using pseuoorders, European J. Combinatorics 44 (2015), 208–217]. Furthermore, we establish the relationships between ordered regular equivalence relations and weak pseudoorders on an ordered semihypergroup, and give some homomorphism theorems of ordered semihypergroups, which are generalizations of similar results in ordered semigroups.
Stability problems and numerical integration on the Lie group SO(3) × R
3 × R
3
Authors: Pop Camelia , Ene Remus-Daniel
Published: March 2018

The paper is dealing with stability problems for a nonlinear system on the Lie group SO(3) × R
3 × R
3. The approximate analytic solutions of the considered system via Optimal Homotopy Asymptotic Method are presented, too.
Rank relations between a {0, 1}-matrix and its complement
Authors: Ma Chao , Zhong Jin
Published: March 2018

Let A be a {0, 1}-matrix and r(A) denotes its rank. The complement matrix of A is defined and denoted by Ac
= J − A, where J is the matrix with each entry being 1. In particular, when A is a square {0, 1}-matrix with each diagonal entry being 0, another kind of complement matrix of A is defined and denoted by
A
= J − I − A, where I is the identity matrix. We determine the possible values of r(A) ± r(Ac
) and r(A) ± r(
A
) in the general case and in the symmetric case. Our proof is constructive.
On some fixed point results for (s, p, α)-contractive mappings in b-metric-like spaces and applications to integral equations
Authors: Zoto Kastriot , Radenović Stojan , Ansari Arslan H.
Published: March 2018

In this work, we introduce the notions of (s, p, α)-quasi-contractions and (s, p)-weak contractions and deduce some fixed point results concerning such contractions, in the setting of b-metric-like spaces. Our results extend and generalize some recent known results in literature to more general metric spaces. Moreover, some examples and applications support the results.
Influence of natural dye adsorption on the structural, morphological and optical properties of TiO2based photoanode of dye-sensitized solar cell
Authors: Hossain M. Khalid , Pervez M. F. , Uddin M. Jalal , Tayyaba S. , Mia M. N. H. , Bashar M. S. , Jewel M. K. H. , Haque M. A. S. , Hakim M. A. , Khan Mubarak A.
Published: March 2018

Porous photoanodes of dye-sensitized solar cells (DSSCs) can adsorb specific type of natural or organic dyes. Adsorption of the dye results in a change of the structural, morphological and optical characteristics of the photoanode. In this work, we present a comparative study on the adsorption effect of natural dye (Curcuma Longa sp.) on the structural, morphological and optical properties of mesoporous titanium dioxide (TiO2) photoanode on indium tin oxide (ITO) coated glass. A number of investigations including XRD, UV-Vis spectroscopy, EDS, and SEM were carried out to observe the variations due to adsorbed dye on TiO2surface. XRD characterization revealed the effect of dye adsorption on specific surface area (SSA), crystallite size, and morphological index (MI). In this case, increasing SSA with decreasing particle size was found for both dye adsorbed and dye free DSSC photoanode samples. Also, the MI and SSA were found to be directly and inversely proportional to the crystallite size respectively. UV-Vis-NIR spectroscopy showed that dye adsorption changes the light absorption, transmittance, and optical bandgap of the photoanode. Average atomic mass percentage of titanium (Ti) and oxygen (O) obtained from EDS analysis proved the presence of TiO2in the mesoporous photoanode. In SEM images, significant morphological changes of mesoporous TiO2 surface appeared because of dye adsorption.
Electrical properties and Mott parameters of polycrystalline diamond films synthesized by HF CVD method from hydrogen/methanol gas mixture
Authors: Banaszak-Piechowska Agnieszka , Fabisiak Kazimierz , Staryga Elżbieta , Paprocki Kazimierz
Published: March 2018

The influence of diamond crystallinity and preferred orientation on electronic conductivity of synthetic diamond films grown by hot filament chemical vapor deposition (HFCVD) was investigated. The CVD diamond films of different morphologies and crystallite sizes varying from 36 nm to 67 nm, measured in h2 2 0i direction were considered. The charge transport mechanism in the diamond samples was studied using temperature dependent DC conductivity measurements. The obtained results showed that in the temperature range of 90 K to 300 K charge transport is realized via Variable Range Hopping (VRH, m = 1/4) mechanism. Using VRH model, the Mott parameters were evaluated i.e. density of states at Fermi level N(EF) (0.22 × 1015 eV-1·cm-3 to 1.7 × 1015 eV-1·cm-3), hopping energy W (43.5 meV to 142.3 meV) and average hopping distance R (1.49 × 10-5cm to 2.56 × 10-5cm). It was shown that above mentioned parameters strongly depend on diamond film preferential orientation.
Influence of doping with Co, Cu, Ce and Fe on structure and photocatalytic activity of TiO2nanoparticles
Authors: Wojcieszak Damian , Mazur Michal , Kaczmarek Danuta , Domaradzki Jaroslaw
Published: March 2018

In this paper, structural and photocatalytic properties of TiO2nanopowders doped with 1 at.% of cerium, cobalt, cooper and iron have been compared. Nanoparticles were synthesized by sol-gel technique and characterized by SEM, EDS and XRD methods. Moreover, their photocatalytic activity was determined based on decomposition of methyl orange. Results were compared with undoped powder. The structural investigations have revealed that all prepared nanopowders were nanocrystalline and had TiO2-anatase structure. The average size of crystallites was ca. 4 nm to 5 nm. The distribution of the dopant was homogenous in case of all manufactured powders. Moreover, for TiO2doped with Co, Ce and Cu, aggregation effect was not as large as for TiO2:Fe. The results of photocatalytic decomposition showed that self-cleaning activity of all prepared nanopowders was higher as compared to undoped one. Due to the efficiency of these reactions (after 5 hours) nanopowders can be ordered as: TiO2:Co > TiO2:Ce > TiO2:Cu > TiO2:Fe > TiO2.
Schattenkapitel – NS-Unternehmensgeschichtsschreibung in der Bundesrepublik seit 1945 zwischen Öffentlichkeitsarbeit und Wissenschaft
Authors: Brünger Sebastian
Published: March 2018

The development of corporate history writing in the Federal Republic has been characterized by a striking relationship between company histories written or initialized by corporations and the slowly institutionalizing academic business history – in short: between public relations and science. Moreover, corporate history writing was closely related to the dispute over the Nazi past of major German companies. Relieving narrative patterns such as those of the «decent merchant» have determined the historical self-image of large companies for decades. By contrast, enterprise-funded contract research since the 1990s has been fundamentally different in its results from older commissioned hagiographies – the effect, however was the same: a promotional image gain for the companies. Thus, a constant remains to be recorded: From the Nuremberg economic trials (Flick, Krupp, IG Farben) and the trial Deutsche Bank vs. Czichon on the founding of the Gesellschaft für Unternehmensgeschichte to the boom of Nazi contract research – in the discourse on Nazi history of German companies, historical science has always taken an important legitimization function for the companies. By now, companies have learned that only proven independent research achieves the desired publicity effect of credibility and can counteract media scandalization dynamics.
After the Gold Rush. Ursprünge und Wirkungen der Forschungskonjunktur «Unternehmen im Nationalsozialismus»
Authors: Schanetzky Tim
Published: March 2018

After the Gold Rush. Origins and Outcomes of the Research Boom «Business in the Third Reich» This article starts with a preliminary statistical reconstruction of the research boom «Business in the Third Reich». Its beginnings during the mid-90s resembled a broader change of attitudes towards the history of the Third Reich and the Holocaust in particular. While this «universalization» of Holocaust memory and the accompanying shift in U.S. foreign policy is well known, the article adds a business historian's perspective and emphasizes the changes of the corporate world of the late 90s: German big business went global and were increasingly dependent on the American market, its financial institutions and the general public of the U.S. As the origins of the research boom were mainly non-academic, the article inquires how business historians reflected on scientific autonomy and conflict of interest in a field dominated by commissioned research. Strikingly, pragmatism prevailed and academics showed little interest in the current state of research on application-oriented science. In a last step, the article discusses the scientific repercussions of the massive surge in demand for commissioned histories. Subsequently, business history tended to address the ever-same set of research questions on corporate action during the 30s and 40s, while the acquisition of corporate funding also made for a distorted choice of objects.
Convergent Spinal Circuits Facilitating Human Wrist Flexors
Authors: Aguiar Stefane A. , Baker Stuart N.
Published: March 2018

Noninvasive assessment of spinal circuitry in humans is limited, especially for Ib pathways in the upper limb. We developed a protocol in which we evoke the H-reflex in flexor carpi radialis (FCR) by median nerve stimulation and condition it with electrical stimulation above motor threshold over the extensor carpi radialis (ECR) muscle belly. Eighteen healthy adults (8 male, 10 female) took part in the study. There was a clear reflex facilitation at a 30 ms interstimulus interval (ISI) and suppression at a 70 ms ISI, which was highly consistent across subjects. We investigated the following two hypotheses of the possible source of the facilitation: (1) ECR Ib afferents from Golgi tendon organs, activated by the twitch following ECR stimulation; and (2) FCR afferents, from spindles and/or Golgi tendon organs, activated by the wrist extension movement that follows ECR stimulation. Several human and monkey experiments indicated a role for both of these sets of afferents. Our results provide evidence for a spinal circuit in which flexor motoneurons receive convergent excitatory input from flexor afferents as well as from extensor Ib afferents; this circuit can be straightforwardly assessed noninvasively in humans.

SIGNIFICANCE STATEMENTHere we described a novel spinal circuit, which is easy to assess noninvasively in humans. Understanding this circuit in more detail could be beneficial for the design of clinical tests in neurological conditions.
Intralimb and Interlimb Cutaneous Reflexes during Locomotion in the Intact Cat
Authors: Hurteau Marie-France , Thibaudier Yann , Dambreville Charline , Danner Simon M. , Rybak Ilya A. , Frigon Alain
Published: March 2018

When the foot contacts an obstacle during locomotion, cutaneous inputs activate spinal circuits to ensure dynamic balance and forward progression. In quadrupeds, this requires coordinated reflex responses between the four limbs. Here, we investigated the patterns and phasic modulation of cutaneous reflexes in forelimb and hindlimb muscles evoked by inputs from all four limbs. Five female cats were implanted to record muscle activity and to stimulate the superficial peroneal and superficial radial nerves during locomotion. Stimulating these nerves evoked short-, mid-, and longer-latency excitatory and/or inhibitory responses in all four limbs that were phase-dependent. The largest responses were generally observed during the peak activity of the muscle. Cutaneous reflexes during mid-swing were consistent with flexion of the homonymous limb and accompanied by modification of the stance phases of the other three limbs, by coactivating flexors and extensors and/or by delaying push-off. Cutaneous reflexes during mid-stance were consistent with stabilizing the homonymous limb by delaying and then facilitating its push-off and modifying the support phases of the homolateral and diagonal limbs, characterized by coactivating flexors and extensors, reinforcing extensor activity and/or delaying push-off. The shortest latencies of homolateral and diagonal responses were consistent with fast-conducting disynaptic or trisynaptic pathways. Descending homolateral and diagonal pathways from the forelimbs to the hindlimbs had a higher probability of eliciting responses compared with ascending pathways from the hindlimbs to the forelimbs. Thus, in quadrupeds, intralimb and interlimb reflexes activated by cutaneous inputs ensure dynamic coordination of the four limbs, producing a whole-body response.

SIGNIFICANCE STATEMENTThe skin contains receptors that, when activated, send inputs to spinal circuits, signaling a perturbation. Rapid responses, or reflexes, in muscles of the contacted limb and opposite homologous limb help maintain balance and forward progression. Here, we investigated reflexes during quadrupedal locomotion in the cat by electrically stimulating cutaneous nerves in each of the four limbs. Functionally, responses appear to modify the trajectory or stabilize the movement of the stimulated limb while modifying the support phase of the other limbs. Reflexes between limbs are mediated by fast-conducting pathways that involve excitatory and inhibitory circuits controlling each limb. The comparatively stronger descending pathways from cervical to lumbar circuits controlling the forelimbs and hindlimbs, respectively, could serve a protective function.
FARKLI DONDURMA VE ÇÖZÜNDÜRME YÖNTEMLERİ İLE ÖN İŞLEM UYGULAMALARININ MANDALİNA VE ÇİLEKTE KALİTE ÖZELLİKLERİ ÜZERİNE ETKİLERİ
Authors: Koç Mehmet , Devseren Esra , Yılmaz Tuğçe , Petmez Berrak , Okut Dilara , Kaymak-Ertekin Figen
Published: March 2018

Bu çalışmada mandalina ve
çileğin, dondurulması ve çözündürülmesi aşamasında uygulanan ön işlemlerin,
dondurma ve çözündürme yöntemlerinin son ürün kalitesi üzerine etkisi
incelenmiştir. Ön işlem olarak sakkaroz ve sitrik asit çözeltilerine daldırma
işlemi uygulanırken, donma yöntemi olarak hızlı donma (IQF, -15ºC) ve
konvansiyonel statik yöntemler (-18ºC ve -24ºC) uygulanmıştır. Çözündürme
işlemi ise ev tipi buzdolabında (4ºC, 4 saat) ve mikrodalga fırında (2 dak)
gerçekleştirilmiştir. Dondurma işlemi öncesi sakkaroz çözeltisine daldırılmış
örneklerin renk ve dokusal özellikleri gelişirken, donma sonrası çözünme
kayıpları azalmıştır. Ön işlem olarak sitrik asit çözeltisine daldırılmış
örneklerin ise çözünme sonrası C vitaminini daha iyi koruduğu belirlenmiştir.
Hızlı donma, çözünme kaybını konvansiyonel yöntemlere göre oldukça azaltmıştır.
Mikrodalga çözündürme işlemi ise çözünme kaybı açısından buzdolabında
çözündürme işlemine göre daha avantajlıdır. Hızlı dondurma yöntemi zaman ve
kalite kayıplarını azaltmasıyla öne çıkmaktadır.
De novo HNF1 homeobox B mutation as a cause for chronic, treatment-resistant hypomagnesaemia
Authors: Stiles C E , Thuraisingham R , Bockenhauer D , Platts L , Kumar A V , Korbonits M
Published: March 2018

29-year-old female presenting with an 8-year history of unexplained hypomagnesaemia, which was severe enough to warrant intermittent inpatient admission for intravenous magnesium. Urinary magnesium was inappropriately normal in the context of hypomagnesaemia indicating magnesium wasting. Ultrasound imaging demonstrated unilateral renal cysts and computed tomography of kidneys, ureters and bladder showed a bicornuate uterus. Referral to genetic services and subsequent testing revealed ade novo HNF1Bdeletion.

Learning points:

HNF1Bloss-of-function mutations are one of the most common monogenic causes of congenital anomalies of the kidney and urinary tract.

Those withHNF1Bmutations may have some of a constellation of features (renal and hepatic cysts, deranged liver function tests, maturity onset diabetes of the young type 5 (MODY5), bicornuate uterus, hyperparathyroidism, hyperuricaemic gout, but presenting features are highly heterogeneous amongst patients and no genotype/phenotype correlation exists.

HNF1Bmutations are inherited in an autosomal dominant pattern but up to 50% of cases arede novo.

HNF1Bmutations can be part of the Chr17q12 deletion syndrome, a contiguous gene deletion syndrome.

Inorganic oral magnesium replacements are generally poorly tolerated with side effects of diarrhoea. Organic magnesium compounds, such as magnesium aspartate, are better absorbed oral replacement therapies.
Low carbohydrate diet and improved glycaemic control in a patient with type one diabetes
Authors: Eiswirth Mirjam , Clark Ewan , Diamond Michael
Published: March 2018

We present the case of an adult female with type 1 diabetes, whose HbA1c was trending at 58 mmol/mol (7.5%) for the past 3 years. In August 2016, she reduced her total daily carbohydrate intake to 30–50 g and adjusted her other macronutrients to compensate for the calorific deficit. Her HbA1c fell to 34 mmol/mol (5.3%) by January 2017 and average daily blood glucose readings decreased significantly from 10.4 to 6.1 mmol/L. Moreover, she observed a marked reduction of average daily glucose variability. Notably, there were no significant episodes of hypo- or hyperglycaemia and her lipid profile remained static. Subjectively, she described an improvement in her quality of life and the dietary transition was extremely well tolerated. We discuss these findings in detail and the potential clinical benefits for patients with type 1 diabetes that can be gained by following a low carbohydrate diet.

Learning points:

A low carbohydrate diet was found to substantially reduce HbA1c values and blood glucose (BG) variability, as well as causing a significant reduction in average daily glucose values in a patient with T1DM.

Although further research is warranted, low carbohydrate diets in patients with T1DM have the potential to positively impact long-term morbidity and mortality through reduction of BG variability and average daily BG values.

The diet was well tolerated and not associated with any adverse effects within this study.
Nivolumab-induced fulminant diabetic ketoacidosis followed by thyroiditis
Authors: Tzoulis Ploutarchos , Corbett Richard W , Ponnampalam Swarupini , Baker Elly , Heaton Daniel , Doulgeraki Triada , Stebbing Justin
Published: March 2018

Five days following the 3rd cycle of nivolumab, a monoclonal antibody, which acts as immune checkpoint inhibitor against the programmed cell death protein-1, for metastatic lung adenocarcinoma, a 56-year-old woman presented at the hospital critically ill. On admission, she had severe diabetic ketoacidosis (DKA), as evidenced by venous glucose of 47 mmol/L, blood ketones of 7.5 mmol/L, pH of 6.95 and bicarbonate of 6.6 mmol/L. She has had no personal or family history of diabetes mellitus (DM), while random venous glucose, measured 1 week prior to hospitalisation, was 6.1 mmol/L. On admission, her HbA1c was 8.2% and anti-GAD antibodies were 12 kIU/L (0–5 kU/L), while islet cell antibodies and serum C-peptide were undetectable. Nivolumab was recommenced without the development of other immune-mediated phenomena until 6 months later, when she developed hypothyroidism with TSH 18 U/L and low free T4. She remains insulin dependent and has required levothyroxine replacement, while she has maintained good radiological and clinical response to immunotherapy. This case is notable for the rapidity of onset and profound nature of DKA at presentation, which occurred two months following commencement of immunotherapy. Despite the association of nivolumab with immune-mediated endocrinopathies, only a very small number of patients developing type 1 DM has been reported to date. Patients should be closely monitored for hyperglycaemia and thyroid dysfunction prior to and periodically during immunotherapy.

Learning points:

Nivolumab can induce fulminant type 1 diabetes, resulting in DKA.

Nivolumab is frequently associated with thyroid dysfunction, mostly hypothyroidism.

Nivolumab-treated patients should be monitored regularly for hyperglycaemia and thyroid dysfunction.

Clinicians should be aware and warn patients of potential signs and symptoms of severe hyperglycaemia.
Muscarinic M2 receptor promotes vasopressin synthesis in mice supraoptic nuclei
Authors: Nagano Hiroshi , Sobue Yuki , Matsuyama Hayato , Saito Shoichiro , Sakai Hiroki , Alom Firoj , Tanahashi Yasuyuki , Ishii Toshiaki , Unno Toshihiro
Published: March 2018

Muscarinic acetylcholine receptors have been suggested to be implicated in arginine–vasopressin secretion because intracerebroventricular muscarinic agonist administration induces arginine–vasopressin release into the circulation. Although which subtype is involved in the regulation of arginine–vasopressin secretion is unclear, M2 receptors have been reported to be highly expressed in the hypothalamus. In the present study, M2 receptor-knockout mice were used to elucidate whether M2 receptor regulates arginine–vasopressin synthesis in the paraventricular nuclei and supraoptic nuclei of the hypothalamus. The number of arginine–vasopressin-immunoreactive neurons in M2 receptor-knockout mice was significantly decreased in the supraoptic nuclei, but not in the paraventricular nuclei compared with wild-type mice. Plasma arginine–vasopressin level in M2 receptor-knockout mice was also significantly lower than in the wild-type mice. Urinary volume and frequency as well as water intake in M2 receptor-knockout mice were significantly higher than those in wild-type mice. The V2 vasopressin receptor expression in kidneys of M2 receptor-knockout mice was comparable with that of wild-type mice, and increased urination in M2 receptor-knockout mice was significantly decreased by administration of desmopressin, a specific V2 receptor agonist, suggesting that V2 receptors in the kidneys of M2 receptor-knockout mice are intact. These results suggest that M2 receptors promote arginine–vasopressin synthesis in the supraoptic nuclei and play a role in the regulation and maintenance of body fluid.
Cold Shock as a Screen for Genes Involved in Cold Acclimatization in Neurospora crassa
Authors: Watters Michael K , Manzanilla Victor , Howell Holly , Mehreteab Alexander , Rose Erik , Walters Nicole , Seitz Nicholas , Nava Jacob , Kekelik Sienna , Knuth Laura , Scivinsky Brianna
Published: March 2018

When subjected to rapid drops of temperature (cold shock), Neurospora responds with a temporary shift in its morphology. This report is the first to examine this response genetically. We report here the results of a screen of selected mutants from the Neurospora knockout library for alterations in their morphological response to cold shock. Three groups of knockouts were selected to be subject to this screen: genes previously suspected to be involved in hyphal development as well as knockouts resulting in morphological changes; transcription factors; and genes homologous to E. coli genes known to alter their expression in response to cold shock. A total of 344 knockout strains were subjected to cold shock. Of those, 118 strains were identified with altered responses. We report here the cold shock morphologies and GO categorizations of strains subjected to this screen. Of strains with knockouts in genes associated with hyphal growth or morphology, 33 of 131 tested (25%) showed an altered response to cold shock. Of strains with knockouts in transcription factor genes, 30 of 145 (20%) showed an altered response to cold shock. Of strains with knockouts in genes homologous to E. coli genes which display altered levels of transcription in response to cold shock, a total of 55 of 68 tested (81%) showed an altered cold shock response. This suggests that the response to cold shock in these two organisms is largely shared in common.
Impulsive Choice in Mice Lacking Paternal Expression ofGrb10Suggests Intragenomic Conflict in Behavior
Authors: Dent Claire L , Humby Trevor , Lewis Katie , Ward Andrew , Fischer-Colbrie Reiner , Wilkinson Lawrence S , Wilkins Jon F , Isles Anthony R
Published: March 2018

The imprinted gene Grb10 is expressed in the brain from the paternal copy only. Here, Dent et al. show that paternal Grb10 regulates impulsive choices, i.e. whether an animal chooses a smaller food reward...

Imprinted genes are expressed from one parental allele only as a consequence of epigenetic events that take place in the mammalian germ line and are thought to have evolved through intragenomic conflict between parental alleles. We demonstrate, for the first time, oppositional effects of imprinted genes on brain and behavior. Specifically, we show that mice lacking paternal Grb10 make fewer impulsive choices, with no dissociable effects on a separate measure of impulsive action. Taken together with previous work showing that mice lacking maternal Nesp55 make more impulsive choices, this suggests that impulsive choice behavior is a substrate for the action of genomic imprinting. Moreover, the contrasting effect of these two genes suggests that impulsive choices are subject to intragenomic conflict and that maternal and paternal interests pull this behavior in opposite directions. Finally, these data may also indicate that an imbalance in expression of imprinted genes contributes to pathological conditions such as gambling and drug addiction, where impulsive behavior becomes maladaptive.
Detection of coronary artery disease by reduced features and extreme learning machine
Authors: Singh Ram Sewak , Saini Barjinder Singh , Sunkaria Ramesh Kumar
Published: March 2018

Objective. Cardiovascular diseases generate the highest mortality in the globe population, mainly due to coronary artery disease (CAD) like arrhythmia, myocardial infarction and heart failure. Therefore, an early identification of CAD and diagnosis is essential. For this, we have proposed a new approach to detect the CAD patients using heart rate variability (HRV) signals. This approach is based on subspaces decomposition of HRV signals using multiscale wavelet packet (MSWP) transform and entropy features extracted from decomposed HRV signals. The detection performance was analyzed using Fisher ranking method, generalized discriminant analysis (GDA) and binary classifier as extreme learning machine (ELM). The ranking strategies designate rank to the available features extracted by entropy methods from decomposed heart rate variability (HRV) signals and organize them according to their clinical importance. The GDA diminishes the dimension of ranked features. In addition, it can enhance the classification accuracy by picking the best discerning of ranked features. The main advantage of ELM is that the hidden layer does not require tuning and it also has a fast rate of detection.Methodology. For the detection of CAD patients, the HRV data of healthy normal sinus rhythm (NSR) and CAD patients were obtained from  a standard database. Self recorded data as normal sinus rhythm (Self_NSR) of healthy subjects were also used in this work. Initially, the HRV time-series was decomposed to 4 levels using MSWP transform. Sixty two features were extracted from decomposed HRV signals by non-linear methods for HRV analysis, fuzzy entropy (FZE) and Kraskov nearest neighbour entropy (K-NNE). Out of sixty-two features, 31 entropy features were extracted by FZE and 31 entropy features were extracted by K-NNE method. These features were selected since every feature has a different physical premise and in this manner concentrates and uses HRV signals information in an assorted technique. Out of 62 features, top ten features were selected, ranked by a ranking method called as Fisher score. The top ten features were applied to the proposed model, GDA with Gaussian or RBF kernal + ELM having hidden node as sigmoid or multiquadric. The GDA method transforms top ten features to only one feature and ELM has been used for classification.Results. Numerical experimentations were performed on the combination of datasets as NSR-CAD and Self_NSR- CAD subjects. The proposed approach has shown better performance using top ten ranked entropy features. The GDA with RBF kernel + ELM having hidden node as multiquadric method and GDA with Gaussian kernel + ELM having hidden node as sigmoid or multiquadric method achieved an approximate detection accuracy of 100% compared to ELM and linear discriminant analysis (LDA)+ELM for both datasets. The subspaces level-4 and level-3 decomposition of HRV signals by MSWP transform can be used for detection and analysis of CAD patients.
OBTAINING ADEQUATE SURGICAL MARGIN STATUS IN BREAST-CONSERVATION THERAPY: INTRAOPERATIVE ULTRASOUND-GUIDED RESECTION VERSUS SPECIMEN MAMMOGRAPHY
Authors: Pop Maria Mihaela , Cristian Silviu , Hanko-Bauer Orsolya , Ghiga Dana Valentina , Georgescu Rares
Published: March 2018

Background and aim. The purpose of breast-conserving surgery (BCS) for women with cancer is to perform an oncological radical procedure with disease-free margins at the final histological assessment and with the best aesthetic result possible. Intraoperative resected specimen ultrasound and intraoperative resected specimen mammography may reduce the rates of positive margins and reexcision among patients undergoing conserving therapy. Our objective is to compare the two methods with the histopathological  results for a preset cut off and asses which parameters can influence the positive margin status.Method. A prospective study was performed on 83 patients who underwent breast conservation surgery for early breast cancer (pT1-3a pN0-1 M0) between 2014 and 2016. After excision the specimen was oriented in the operating room by the surgeon. Metallic clips and threads were placed on margins: one clip and the long thread at 12 o'clock, two clips and the short threads at 9 o'clock. The next step was intraoperative ultrasound assessment of the specimen. For the margins under 2 mm we performed selective margin shaving, followed by mammography to identify and document the lesion and finally histopathological examination of the specimen with reporting the gross and microscopic margins. The positive margins required re-excision or boost of radiation at the posterior or anterior margins, depending on the case.Results. We set a cut-off at 2 mm. The sensitivity and specificity of the intraoperative margin assessment via the ultrasound method were 90.91% (95% CI 70.84-98.88%) and 67.21% (95% CI 54-78.69%) respectively. The sensitivity and specificity of the intraoperative margin assessment via the mammographic procedure were 45.45% (95% CI 24.39-67.79%) and 85.25% (95% CI 73.83-93.02%) respectively. There was positive correlation between the histopathological and intraoperative ultrasound exam (p=0.018) and negative correlation between the histopathological exam and the post-operative mammographic exam (p=0.68). We found a positive correlation between the positive margin status and age (<40), preoperative chemotherapy, intraductal carcinoma, inflammatory process around the tumor, and the immunohistochemical triple negative profile.Conclusions. According to our results, the intraoperative ultrasound of the breast specimen for a cutt-off at 2 mm can decrease the rates of margin positivity compared to the mammographic procedure and has the potential to diminish the number of subsequent undesired re-excisions.
Imaging modalities for temporomandibular joint disorders: an update
Authors: Talmaceanu Daniel , Lenghel Lavinia Manuela , Bolog Nicolae , Hedesiu Mihaela , Buduru Smaranda , Rotar Horatiu , Baciut Mihaela , Baciut Grigore
Published: March 2018

The diagnosis and management of temporomandibular disorders (TMD) require both clinical and imaging examinations of the temporomandibular joint (TMJ). A variety of modalities can be used to image the TMJ, including magnetic resonance imaging (MRI), computed tomography (CT), cone beam CT, ultrasonography, conventional radiography. The present review outlines the indications of the most frequently used imaging techniques in TMD diagnosis.Because of the anatomic complexity of the TMJ, imaging can be difficult. Choosing the proper imaging technique is essential. Conventional radiography, nowadays, is of limited interest. The use of flat plane films for TMJ pathology is not sufficient, because this joint requires three dimensional imaging views. Osseous changes are better visualized with CT and cone beam CT. Cone beam CT provides high-resolution multiplanar reconstruction of the TMJ, with a low radiation dose, without superimposition of the bony structures. MRI is a noninvasive technique, considered to be the gold standard in imaging the soft tissue components of the TMJ. MRI is used to evaluate the articular disc in terms of location and morphology. Moreover, the early signs of TMD and the presence of joint effusion can be determined. High-resolution ultrasonography is a noninvasive, dynamic, inexpensive imaging technique, which can be useful in diagnosing TMJ disc displacements. The diagnostic value of high-resolution ultrasonography is strictly dependent on the examiner’s skills and on the equipment used.
Producción de carbón en Colombia e inversión extranjera directa
Authors: Moreno Andrés
Published: March 2018

A partir de una revisión de cifras y datos sobre la producción de carbón en Colombia se identifican los retos que el Estado y la sociedad deben asumir si se espera un real aprovechamiento de este recurso natural no renovable.
El Vivir bien, una crítica cultural del capitalismo
Authors: Gómez Muller Alfredo
Published: March 2018

Las nuevas Constituciones políticas de Ecuador y Bolivia introducen, por primera vez en la historia de América Latina, términos provenientes de lenguas nativas: sumak kawsay, en lengua kichwa de Ecuador y suma qamaña, en lengua aymara de Bolivia. Traducidos al castellano por Buen vivir y Vivir bien, ambas nociones tienen un significado ético, axiológico y crítico de un estado de la cultura hoy en día hegemónico que conlleva un modelo percibido como insostenible ecológicamente y como insoportable socialmente. En sus diversas variantes culturalista e interculturalista, las políticas de (re)construcción del Vivir Bien, que surgen de las movilizaciones indígenas y plebeyas en Ecuador y en Bolivia desde la década 1980, exigen un “cambio civilizatorio” que en su dimensión crítica reviste la forma de una crítica cultural del capitalismo, basada en una concepción de la espiritualidad que se juega en la calidad de las relaciones interhumanas y de la relación humana con el mundo llamado natural.
Roa, T., Roa, M., Toloza, J. y Navas, L. (Coords.). (2017). Como el agua y el aceite. Conflictos socioambientales por la extracción petrolera. Bogotá D.C.: Centro Nacional Salud, Ambiente y Trabajo, CENSAT Agua Viva, 287 pp.
Authors: Gomez Lisa
Published: March 2018

Como el agua y el aceite. Conflictos socioambientales por la extracción petrolera, es un documento coordinado por Tatiana Roa Avendaño, María Roa García, Jessica Toloza Chaparro y Luisa Navas Camacho, recoge 16 relatos de mujeres acerca de los conflictos socioambientales en cuatro zonas del país: el Piedemonte amazónico-orinocense, la cordillera Oriental, la zona Caribe y la cuenca del Magdalena.
A szobafestő szerződése Fabricius Jakab Ignác Edelényben (1780), Johann Binnerth és Joseph Lerch Márkusfalván (1788, 1792)
Authors: Jávor Anna
Published: March 2018

A growing number of 18th century ornamental wall paintings have been explored and published in country houses and burgher’s dwellings. They are never signed, the painters are usually anonymous. A few archival documents, contracts that may be associated with such assignments are presented now.

Jakab Ignác Fabricius of Miskolc signed a contract with Countess Ludmilla Forgách to decorate a room and correct the decoration of another in Edelény in 1780. Since the contiguous figural decoration of the walls of six rooms of this mansion has been attributed to Ferenc Lieb (on the basis of a contract of 1769 and other works of his), the purely ornamental decor of the seventh room in the western wing of the mansion might have been the work of Fabricius, who was the son-in-law of Lieb, by the way. Other painters and gilders were at work in Edelény, too: the Latin contract of János Voronieski dated 1765 also covers the ornamental decoration of a room, the presence of István Nits, painter from Eger in 1768 suggests a similar assignment, which were later painted over by Lieb’s murals of rococo figural scenes in 1769–1771.

The rococo reconstruction, extension and decoration of the Máriássy mansion complex at Márkusfalva (Markušovce) took place under the guidance of Farkas Máriássy from the 1770s. The surviving 73 contracts of the work are known from earlier publications, including the contract of 1788 with Johannes Binnerth, a painter from Igló (Spíšská Nová Ves), for the free-handed painting of flowers after sketches. The five smaller and two bigger rooms at issue were in the lateral building to the right (now in ruins). Binnerth’s achievements as a painter and drawing teacher, and his son’s similar ambitions were praised in the press as later as in 1813, too. The Catholic painter who died at the age of 64 in 1814 is documented in the Spíš town from 1783, but his works are not known.

Slovakian research literature has explored the oeuvre of Joseph Lerch (1751–after 1828), Lőcse (Levoča)-based painter born at Szepesszombat (Spíšská Sobotá). His neoclassical late baroque frescoes were signed in the country house at Dobó (Dubavica) and the parish church of Liptóújvár (Liptovský Hrádek); altarpieces and portraits are known by him, in 1804 he was contracted to paint a picture on the curtain of Kassa (Košice) theatre. The widow of Ferenc Máriássy commissioned him in 1792 to decorate five rooms, but in view of the price and Lerch’s known works, this work might have been figural. The decoration was completed, but it has no trace at Márkusfalva; the fresco of the roadside chapel of St John Nepomucene was earlier attributed to him, while the higher quality mythological scenes painted on the walls of the garden pavilion of the mansion („Dardanelles”) still await attribution.
A lőcsei Baumerth festő-fivérekről
Authors: Boda Zsuzsanna
Published: March 2018

The names and the few known works by Johann and Christian Baumerth slightly run into one another in the Hungarian art historical literature. On the basis of the data in registers of birth of the evangelical church in Lőcse (Levoča) became clear that we could talk about two painters who were brothers. Johann Baumerth (11 March, 1788–5 March, 1833) worked as a teacher of drawing in the evangelical secondary school for girls in Lőcse (Levoča). His younger brother Christian (8 May, 1792–18 July, 1824) was the pupil of the painter József Czauczik and wanted to develop his knowledge in the Academy of Arts Vienna. His early work is a memorial leaf of Anna Mária Horváth Stansith, wife of Ferenc Máriássy at her death in 1810. We know a few more works of Johann Baumerth. The engravings of the cities of Rozsnyó (Rožňava) and Igló (Spišská Nová Ves) probably were made after his own drawings around 1820. Two gouache paintings (1810) by him recently appeared in art dealer’s gallery, a romantic style landscape and a biblical genre, which remind us to the early romantic landscape painting of Károly Kisfaludy (1788–1830). One of these pictures, the Shipwreck on stormy sea, was made after the composition by Claude Joseph Vernet.
„Sola scriptura” az aszódi Podmaniczky-kastély dísztermének kifestése és ikonográfiai programja az evangélikus erénytanok összefüggésében
Authors: Serfőző Szabolcs
Published: March 2018

The Podmaniczky Mansion in Aszód was built in 1727– 1730 by János Podmaniczky (1691–1743). In 1767–1772 the building was extended by his sons, János (1716–1786) and Sándor (1723–1786), who resided with their families in the eastern and western wing of the mansion.

In 1776 Sándor Podmaniczky commissioned Johann Lucas Kracker and his assistant, Joseph Zach, specialised in trompe l’oeil architectural painting to fresco the ceremonial hall of the mansion, located at the southern end of the western wing. The ceiling painting features in the centre the allegorical female figure, a Justifying Faith (fides iustificans), holding the Holy Script with the inscription Sola scriptura. She is surrounded by allegories of different virtues, such as Divine Mercy (Caritas Dei), Humility, Generosity, Hospitality, Temperance, Self-restraint and Right Judgement. On the right of the ceiling the female figure of Wisdom is to be seen striking down the Vices. In the four corners of the ceiling further four virtue-allegories are located: Honesty, Fame, Diligence and the Love of Virtues.

The moralizing programme of the vivid ceiling painting is accompanied by grisaille, statue- and relief-like representations on the sidewalls. The illusionistic statues of Seneca and Alexander the Great represent two classical virtues: wisdom and heroic pugnacity. On the longer walls of the hall four illusionistic busts of four Classical deities (Jupiter, Neptune, Pluto and Ceres) represent the four elements. Above them relief-like mythological scenes are to be seen: two episodes from the youth of Bacchus, the story of Apollo and Daphne and finally the contest of Apollo and Pan.

The complex, moralizing iconographic programme conveyed by the wall and ceiling paintings can be interpreted in the context of the Lutheran ethics, as the com missioner himself was of Lutheran confession. Lutheran teachings on ethics have fundamentally differed from the scholastic doctrine on theological and cardinal virtues and have defined a different canon of virtues. This Lutheran virtue’s canon is reflected in the iconography of the ceiling painting to a large extent. The Olympic deities and mythological scenes featuring on the side walls symbolise the material world, as opposed with the spiritual sphere represented by the virtue-allegories on the ceiling. The overall message of the paintings is that living a pious, virtuous life, conducted by faith, avoiding vice and exercising self-restraint leads the soul to heaven, in harmony with the Lutheran doctrine of justification.
A nyírbátori stallum (1511)
Authors: Mikó Árpád
Published: March 2018

From the Calvinist church of Nyírbátor (dedicated to St George in the Middle Ages) the Hungarian National Museum purchased the monumental stalls of a total of 48 seats in 1933. The two parts – both defective – were set up along the northern and southern walls of the church. The dissembled elements of the first rows of the seats were stored in the sanctuary. From the two incomplete stall wings one complete set of choir-stalls was assembled by transferring the marquetry dorsal panels from the southern wing to the northern wing and the original two-row stalls was thus reconstructed. The northern choir-stalls are still part of the permanent historical exhibition of the National Museum, while the incomplete southern stalls are on display in the Báthory István Museum in Nyírbátor. Following the reconstruction work with attention in the Museum, Magda Oberschall Bárány wrote a monograph of the stalls (1938), describing their ideal state, without discussing the structural questions. Important points in the history of the stalls are still unknown. It is not known since when they had been in the Calvinist church, and a more puzzling question is what the function of such a monumental construction was in the parish church of a small country town. The first mention of the stalls dates from the early 18th century. They were repaired a few times over the 19th century at the end of which nascent art historiography also discovered them. The idea of transferring them to a museum was raised several times.

The inscription says the stalls were commission in 1511 by three Báthory brothers: István, György and András, all three actors in the political elite of the late medieval Hungarian kingdom. (Their father András I [†1497] was the brother of the voivode of Transylvania and lord chief justice István II [†1493] and of Miklós I, the humanist bishop of Vác [†1506].) Nearly all elements of the canopied stalls are covered with ornamental carvings, the dorsal panels of the back row being adorned with inlaid designs. The latter include ornamental compositions, allegorical scenes, and illusionistic depictions of half-open cabinets with books and ritual objects on the shelves. Among the marquetry designs are the panels with the Báthory coats of arms and the inscription about the origin of the stalls. On account of the all’antica motifs, the perspectivic trompe l’oeil compositions and the high quality of the whole work the choir-stalls of Nyírbátor are on a par with the finest Italian stalls of the period. They were probably made by Italian masters working in Buda. The – presumed – Hungarian specimens of the kind have perished; the only stalls whose stylistic elements are in kinship with the stalls at issue are the early 16th century stalls in Zagreb cathedral. There is written evidence that a set of the stalls in Zagreb cathedral (1507) was made by Johannes Nicze Florentinus, who also worked in Pest. Despite several attempts, so far no name can be associated with the stalls of Nyírbátor.