bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH UKURAN PERUSAHAAN, PROFITABILITAS, OPINI AUDIT TAHUN SEBELUMNYA, DAN LIKUIDITAS TERHADAP OPINI AUDIT GOING CONCERN PADA PERUSAHAAN TAMBANG DAN AGRICULTURE YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2014-2018
Authors: Yulianto Yulianto , Tutuko Bambang , Larasati Meita
Published: October 2020

ABSTRACTThis study aims to determine how the influence of company size, profitability, previous year's audit opinion, and liquidity on going concern audit opinions in mining and agriculture sector companies that have been listed on the Indonesia Stock Exchange (BEI) for the 2014-2018 period.The population of this research is mining and agriculture sector companies that have been listed on the Indonesia Stock Exchange (IDX). The sample selection technique used was purposive sampling and obtained 7 (seven) companies. The data collection technique used in this study is secondary data, namely tracing the financial statements of mining and agriculture sector companies for 2014-2018 through the IDX website (www.idx.co.id).The results showed that partially company size had no effect on going concern audit opinion with a significance level of 0.457> 0.05. Profitability variable partially affects going-concern audit opinion with a significance level of 0.031> 0.05. The audit opinion variable in the previous year partially influences going-concern audit opinion with a significance level of 0.010> 0.05. The liquidity variable partially has no effect on going concern audit opinion with a significance level of 0.722> 0.05. The effect of company size, profitability, previous year's audit opinion, and liquidity simultaneously affects going-concern audit opinion with a significance level of 0.000 <0.05.
Three new to Russia species of Collema (Collemataceae) from South of Far East
Authors: Makryi T. V. , Skirina I. F.
Published: October 2020

The descriptions and localities of three new for Russia lichen species, Collema callibotrys Tuck. var. callibotrys, C. conglomeratum var. crassiusculum (Malme) Degel., and C. shiroumanum Räsänen var. shiroumanum are provided.
Addition to lichen flora of islands and coast of Peter the Great Bay (the Sea of Japan, Primorie Territory)
Authors: Skirina I. F.
Published: October 2020

Data on 245 lichen species growing on islands and coast of Peter the Great Bay are provided. 87 lichen species are new for the studied territory. Additional information concerning distribution and substrate data is given for 158 lichen species. Vegetation types, distribution and substrate data are recorded for every species.
New and rare liverworts for Republic Sakha (Yakutia)
Authors: Sofronova E. V.
Published: October 2020

Four new and rare liverworts for flora of Yakutia are listed. Data on their localities, substrates, habitats and reproduction are provided.
شِقْشِقَةٌ كورونيَّةٌ مع اللغة العربيَّة
Authors: م.د. أنور شناوي ذياب
Published: October 2020

يركز البحث على أهمية اللغة وأثرها في التغيرات الاجتماعية والسياسية والاقتصادية وبيان قدرتها على خلق الأزمات والصراعات بين الحكومات, وفي الوقت نفسه بيان قدرتها على حلّ هذه المشكلات أو التقليل من أثرها السلبي بين الشعوب.  سيحاول البحث فكّ التعارض بين الضغوط الثقافيَّة التي تواجهها اللغة من جهة , وبين ماتحويه في متنها من كلمات التي وصفها البعض بأنَّها عاجزةٌ عن مسايرة العلم والمعرفة الجديدين. للكشف عن قدرة اللغة العربيَّة على استيعاب الجديد ,وإيجاد البديل المناسب بحسب نواميسها,آخذين بنظر الاعتبار جِدَّة الموضوع وحداثته , وقلة المصادر التي سنحيل عليها , فضلاً عن اعتمادنا على مواقع الصحافة العالميَّة على شبكة الإنترنت , وما تصدره منظمة الصحة العالميَّة من توجيهات وإرشادات وملاحظات على موقعها الرسميّ باللغة العربيَّة , يُضاف إلى ذلك ما يجيء من تصريحات في مؤتمرات صحافيَّة وإعلاميَّة , ومقالات باللغة الانكليزية.
العقوبات فِي إيران الْقَدِيمَة إبّانّ الْعَصْر الأخميني (559- 330ق.م)
Authors: عبَّود سمَّار سعد , مهدي محمد زهراء
Published: October 2020

تهدف هذه الدراسة الموسوم ﺑـ ( العقوبات فِي إيران الْقَدِيمَة إبّانّ الْعَصْر الأخميني (559-330ق.م) إلى تسليط الضوء على العقوبات وانواعها. وتتمثل بالعقوبات الجسدية، والعقوبات التي تُقيد حرية الأشخاص وتسلبها، وعقوبات مالية، وعقوبات نفسية، وتتطرق إلى السلطات التي تفرض هذه العقوبات، وكيفية تنفيذها.
الأبعاد العالمية والإقليمية للتداعيات الاقتصادية لجائحة كوفيد 19 ( فيروس كورونا المستجد)
Authors: نجاة وسيلة بلغنامي , ادوارد نشأت نشأت
Published: October 2020

في ظل ازمة كوفيد19  الذي أثارها الوباء و الذي تسبب في إحداث شلل عالمي ،ألقى بأضراره على كل الدول في مختلف القطاعات الاستراتيجية لاسيما الصحية ، الاجتماعية و الاقتصادية نتيجة التدابير الاحترازية التي فرضتها إجراءات الحجر الصحي ، في هذا الصدد نحاول من خلال هذه الورقة البحثية ابراز واقع تأثير انتشار الفيروس على الاقتصاد العالمي و الاقليمي للدول في ظل تراجع القيم السوقية لأسهم الشركات و أسعار النفظ التي انخفضت الى اقل من 20 دولار أمريكي . ثم تسليط الضوء على اتجاه موازين القوى والعلاقات الدولية بعد تحول بؤرة الفيروس من الصين التي تعد محركاً فعالاً في خطوط التوريد والإمداد العالمي من مصدرا للفيروس الى الوم أ .

في الأخير نعرج على الانعكاسات المالية و المساعدات الدولية المقدمة للتخفيف من وطأة الكارثة

خاصة على الدول الإفريقية .
المنفعة الحدية لحاملات الدلالة في انتاج المعنى للعرض المسرحي العراقي ( مسرحية الظلمة أنموذجاً )
Authors: كاظم علوان الشمري زهير
Published: October 2020

لعل من أهم العلوم التي عاصرت الانسان منذ نشأته الى اليوم هو علم المسرح وعلوم الاقتصاد وذلك لما لهما من علائق وجوبية وحتمية بوجود الانسان وعلاقاته بالبيئة التي ينتمي اليها ومع ان لعلم المسرح وشائج مع الكثير من العلوم الأخرى مثل علم اللغة والفيزياء والسيمياء ، ألا أن علاقته بعلم الاقتصاد مازالت في اطار محدود لذا رأى الباحث ضرورة ايجاد مقتربات بين نظرية المنفعة الحدية الاقتصادية وحاملات الدلالة في انتاجها للمعنى  فتمثلت مشكلة البحث بالسؤال الآتي:

 ما هي المنفعة الحدية لتوظيف حاملات الدلالة لإنتاج المعنى في العرض المسرحي؟

ثم تم تحديد الهدف في محاولة ايجاد مقاربة بين المنفعة الحدية للإنتاج الاقتصادي وحاملات الدلالة باعتبارها وحدات منتجة للمعنى في العرض المسرحي وبعد بيان اهمية البحث وتحديد الحدود ، تناول البحث في اطاره النظري – المبحث الأول مفهوم المنفعة الحدية في علم الاقتصاد وعلاقتها بعناصر العر ض المسرحي كونها وحدات لإنتاج المعني . ثم تناول الباحث في المبحث الثاني مفهوم حاملات الدلالة وتقسيماتها وفق النظريات السيميائية واعتمد تقسيم ( بيرس ) الثلاثي في تحليل العينة . وخرج من الاطار النظري بجملة مؤشرات كانت له معياراً لقياس النتائج ولعل من أهمها أن الاحالة العلاماتية أكثر عملية في انتاج المعنى من المباشرة في الطرح .

وفي الاجراءات اختار الباحث مسرحية الظلمة انموذجاً للبحث وقام بتحليلها وفق المنهج الوصفي التحليلي وبرر اختيارها كونها تتفق واهداف البحث ومشاهدته لها وحصوله على تسجيل لها على قرص مدمج ، ثم توصل الباحث الى جملة نتائج لعل اهمها ، ان المعنى يكون اكثر ثراءً حين تتساوى قيمة الاشباع مع قيمة المنفعة الحدية وبعد ذلك تم تثبيت الاستنتاجات  وبعض المقترحات والتوصيات ، وتثبيت قائمة المصادر والمراجع .
أثر استخدام استراتيجية التعلم العنقودي المطورة في تدريس الرياضيات بالفصول ذات الكثافة العددية على التحصيل الدراسي والميول الرياضية لدى طلاب المرحلة المتوسطة
Authors: بن سعيد آل كحلان ثابت , بن محمد موسى محزري إبراهيم
Published: October 2020

هدف البحث إلى تعّرف أثر استخدام استراتيجية التعلم العنقودي المطورة في تدريس الرياضيات بالفصول ذات الكثافة العددية على التحصيل الدراسي والميول الرياضية لدى طلاب المرحلة المتوسطة، وقد استخدم الباحثان المنهج شبه التجريبي، حيث قام الباحثان باختيار عينة عشوائية لفصول ذو المجموعتين المتكافئتين من الفصول ذات الكثافة العددية أحدهما  مجموعة تجريبية وعددهم (40) طالباً يدرسون وحدة "الجبر: الدوال الخطية" وفقا لاستراتيجية التعلم العنقودي المطورة، والأخرى مجموعة ضابطة وعددهم (40) طالباً يدرسون نفس الوحدة بالطريقة المعتادة، وكانت أداتي البحث عبارة عن اختبار تحصيلي، ومقياس الميول.

وقد أظهرت نتائج البحث وجود فروق دالة احصائياً بين متوسطات درجات المجموعتين التجريبية والضابطة في التطبيق البعدي للاختبار التحصيلي والميول الرياضية، لصالح المجموعة التجريبية، كما أظهرت نتائج البحث الأثر الإيجابي الكبير لاستخدام استراتيجية التعلم العنقودي المطورة على التحصيل الدراسي والميول الرياضية، حيث بلغت قيم مربع إيتا على التوالي: (0.53) و(0.30).
The Ancient City of Babylon
Authors: S. Mahan Mohammed , Muslim Hamza Ghassan
Published: October 2020

Babylon during Nebuchadnezzar II (604-562 BC) was a great city. It had been a large city since Old Babylonian times, but Nebuchadnezzar’s expansion of the city and large-scale rebuilding of important buildings with good baked brick instead of the traditional unbaked mudbrick created something exceptional. Babylon now was larger than Nineveh had been and larger than any of the cities in the known world. The political and economic base for this development was of course that it was the centre of the Neo-Babylonian empire created by Nebuchadnezzar’s father Nabopolassar (625–605 BC) and succeeding the Neo Assyrian empire as the main political entity in the Middle East.

        An attempt for the first time to bring together the main results of the German excavations in Babylon with the main results from the Iraqi excavations there and thereby make use of the available cuneiform documentation and a selected use of the best of the classical tradition. With the help of a GIS software (QGIS) and a BIM program (ArchiCAD) the use of satellite images and aerial photos combined with inspection on the site, the historical development of the site has been studied and a digital research model of Babylon for different periods of the city’s history has been created.

 

       Only main buildings and constructions have been considered and placed in the appropriate historical and archaeological context. Part 1 includes some information about the historical development of buildings and nature in Babylon, the rivers and groundwater in Baybylon, as well as basics about the building materials used in Babylon. Part 2 discuss the city walls and city gates, introductory matters about the history, excavation and other documentations of the walls and gates. The chapter also includes presentation of the walls and gates during Nabopolassar followed by a detailed discussion of the walls and gates during Nebuchadnezzar. The Ištar gate and the area around it with the different levels and the upper level glazed decoration have been treated separately. Detailed interpretations about the palaces, development of the main traditional South Palace and the new constructed North are discussed in part 3. Reasonable suggestions for the Hanging Gardens in the North Palace have be provided.

 

       The temples are discussed in part 4 detailing the Marduk temple and the zikkurrat. The historical development of the four temples reconstructed on the site in Babylon on their old foundations, i.e. Nabû, Ištar, Ašratum, and Ninmaḫ temples, is discussed with indication which levels have been used for the reconstructions. The historical development of the other excavated temples, i.e. the Ninurta and Išḫara temples, are discussed in a similar way. Attention will be paid to the remains of wall decorations in the temples.
MEMFASILITASI ANAK-ANAK UNTUK BELAJAR DALAM MENGHADAPI COVID-19 DI DESA BONTOMATENE KEC. TURATEA
Authors: Risnawati
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh masyarakat dalam waktu tertentu. oleh karena, sifatnya intraku rikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (SI) harus mengikuti KKLP.
MEMFASISLITASI MASYARAKAT MELAWAN REVOLUSI 4.0 DI DESA BONTOMATENE KEC. TURATEA
Authors: karmila
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh masyarakat dalam waktu tertentu. oleh karena, sifatnya intraku rikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (SI) harus mengikuti KKLP.
Jurnal Harian/Mingguan
Authors: YULIANA
Published: October 2020

kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh mahasiswa dalam jangka waktu tertentu. oleh karena, sifatnya intrakurikuler sehingga setiap mahasiswa yang akan menyelesaikan studi perguruan tinggi pada suatu program strata (S1) harus mengikuti KKLP.
MEMFASILITASI ANAK-ANAK UNTUK BELAJAR DALAM MENGHADAPI COVID-19 DI DESA BONTOMATENE KEC. TURATEA
Authors: Surianti
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh masyarakat dalam waktu tertentu. oleh karena, sifatnya intraku rikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (SI) harus mengikuti KKLP.
Conformal action and fisher metric
Authors: Kuyukov Vitaly
Published: October 2020

Conformal action and conformal fisher metric
Van Tongeren (2020) - Face to Face with Death: The Role of Religion in Coping with Suffering
Authors: Van Tongeren Daryl R.
Published: October 2020

Human suffering is a focal point of religion, yet it also poses a problem for many religions: how could a loving God or sacred deity allow evil into the world and pain to torment humanity? Suffering is an existential concern that often erodes meaning, results in cracks in people’s fundamental assumptions about the world, and leaves people prone to existential anxiety. Moreover, suffering also makes threats of death unavoidable or undeniable—they must be directly confronted. In this chapter, I review the existential function of religion, discuss how the nature and content of religious beliefs play a role in how people manage the threats of death created by suffering, and consider how religious responses to death include fighting, freezing, fleeing, and flourishing. I conclude by discussing future areas of research to advance the scientific study of religion through the perspective of existential psychology.
Radicalization and Deradicalization: A qualitative analysis of parallels in relevant risk factors and trigger factors
Authors: Reiter Julia , Doosje Bertjan , Feddes Allard
Published: October 2020

We analysed five narrative interviews with individuals who disengaged from Islamist extremist and Salafist ideologies in an early stage of radicalization (Study 1) and seven semi-structured expert interviews with employees of German deradicalization-programmes (Study 2) to explore which root factors are common to both radicaliza-tion and deradicalization and how they manifest. Employing a coding-reliability ap-proach to Thematic Analyses, we constructed five themes central in radicalization and deradicalization, respectively. Parallels between radicalization and deradicaliza-tion (themes: social surroundings, exclusion vs. acceptance, social status, self-definition, structure / sense of purpose) as well as the specifics of our particular sample – female explorers of religious extremism – and implications for future re-search are discussed.
LET'S SPEND THE NIGHT TOGETHER: A Challenge for Medically Optimal Coronavirus Social Distancing Policies
Authors: Kelley Jonathan , Evans MDR , Kelley Sarah
Published: October 2020

Public health efforts aiming to slow the COVID-19 epidemic and protect the vulnerable by reducing interpersonal contact and increasing interpersonal physical distance have achieved considerable success. About three-quarters of Americans report following all the recommended practices. But there is an elephant in the room: Overnighting – staying overnight at someone else’s home or having them stay overnight at your place -- is rarely mentioned publicly. But we find that overnighting is widespread throughout the epidemic thus far. In the past month, over half American adults had at least one overnight guest and about the same number (but not always the same people) spent at least one night at somebody else's home. The consequences are striking: People who overnight are more than twice as likely to report having had COVID-19. Who overnights? Overnighting is much more common among young adults (over 60% for those 25-34) than among their seniors (dipping below 40% for those age 65 and over). Moreover, risk seekers overnight much more than otherwise-similar risk-averse peers. Data: International Social Science Survey, Round 21, Cohorts 1-7, collected April –September 2020, N=9,474. Methods: Descriptive statistics and OLS.
Re-performing Design
Authors: Meron Yaron
Published: October 2020

Graphic design, as a specific research discipline, has been largely underrepresented in academia, with the literature suggesting this is partially due to difficulties in researching its professional practitioners. Acknowledging such hurdles, this article discusses an experimental study that used dramaturgy as a defamiliarising method for uncovering professional graphic designers’ perceptions of stakeholders. The study collected graphic designer narratives from online forums as well as dramaturgically informed interviews with professional practitioners. The graphic designers’ narratives were converted into a script and used to motivate a troupe of trained actors, who re-performed the narratives during a series of performance workshops. The article argues that this use of trained actors as ‘proxy designers’ created a refractive form of defamiliarisation, allowing previously obfuscated narratives about graphic designers’ perceptions of stakeholders to emerge. Presenting the study as a prototype to inform future research into graphic design and other elusive creative practices, the article also cautions that the amount of defamiliarisation used must be evaluated against the desired outcomes.
GAME DEPENDENCE - CAUSES AND POSSIBLE EFFECTS
Authors:   Sochi State University, Vostryakova P. , Mikhal'kova O. ,   Sochi State University, Graf Ya. ,   Sochi State University
Published: October 2020

The article presents the problem of gambling addiction – its causes and possible consequences. We consider the signs of gambling addiction, its prevention and treatment.
PILOT GEOLOGICAL-GEOPHYSCHEMICAL SCHOOL COURSE "BOWELS OF THE EARTH": PROBLEMS AND ACHIEVEMENTS
Authors:   National Science and Natural History Museum of National Academy of Sciences of Ukraine, Reshetnyk M. , Starokadomsky D. ,   Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine
Published: October 2020

In this paper, the results of the experimental 5-years experimental course "Bowels of the earth" for students in schools in Kiev are presented. Classification of students according to the degree of teaching effectiveness was carried out. The problems in the conduct of the educational process are described.The statistics of students' success and their familiarity with geology as a function of training time are analyzed. A direct correlation was established between the duration of the course and the success of students, and the number of applicants to higher educational geological institutions
Relationship between international law and religion
Authors:   Baku State University Law, Mammadov H. , Mammadova Zh. ,   Baku State University Law
Published: October 2020

This article is devoted to the problems of mutual influence and interaction of international law and religion. In particular, it examines the development of international law and the sources of religion. In addition, which areas of international law are most developed under the influence of religious provisions. The history of international law knows various theories under which international law has improved. The article provides a detailed analysis of these theories and views, noting the institutions of international law that arose directly under the influence of religion. For example, it is noted that under the influence of Relia, the UN Charter codifies the basic principles of international law, etc. In addition, it shows the challenges of religion to international law and relations in the era of globalization in the twenty-first century, which led even to the undermining of modern international relations and traditional religious concepts caused by the " return of religion” in international relations; secondly, it presents and discusses the research path of religion and international relations. Finally, a brief analysis of the 2 impact of the global revival of religion and the ”return of religion" in international law and international relations has been carried out
COMPARATIVE ANALYSIS OF PERFORMANCE TECHNIQUE ELEMENT EXTENSION LIFT FOR GYMNASTS AND GYMNASTS AT DIFFERENT STAGES OF LEARNING
Authors:   Russian State University of Physical Education, Sport, Youth, and Tourism, Parakhin V. , Sobitova M. ,   Russian State University of Physical Education, Sport, Youth, and Tourism
Published: October 2020

The article describes a comparative analysis of the technique of performing the gymnastic element with extension in gymnasts and gymnasts of different qualifications
Corporate Sustainability
Authors: Joy Varghese
Published: October 2020

This is a review of the concept corporate sustainability. Being the most widely discussed and deliberated topic in the management and corporate literature, this concept has been defined by many academic scholars with their own specific approach. This article makes an attempt to review these approaches and will examine them in the context of the principles of the social quality approach (SQA). The progress and relevance of the United Nation's 2030 sustainable development is also reviewed. The conceptual and methodological redefinition given by SQA scholars and the reasons for their rejection of the tripartite approach to defining sustainability provided in the UN Brundtland Report is also discussed in order to provide a basis for further research into the issue of sustainability and how it relates to the SQA.
ЭФФЕКТИВНОСТЬ ОПРЕДЕЛЕНИЯ 5-МЕТИЛЦИТОЗИНА В ДНК КЛЕТОК ESCHERICHIA COLI, НЕСУЩИХ ГЕНЫ БАКТЕРИАЛЬНЫХ ДНК- МЕТИЛТРАНСФЕРАЗ, С ПОМОЩЬЮ УСТАНОВКИ OXFORD NANOPORE
Authors:   Институт общей генетики им. Н.И. Вавилова РАН, Ильинский И.В. ,   ООО «Генотек», Козлова Е.М. ,   Институт общей генетики им. Н.И. Вавилова РАН,   Московский физико-технический институт, Дегтярев С.Х. ,   НПО «СибЭнзим», Янковский Н.К. ,   Институт общей генетики им. Н.И. Вавилова РАН,   Московский государственный университет имени М.В. Ломоносова, Макеев В.Ю. ,   Институт общей генетики им. Н.И. Вавилова РАН,   Московский физико-технический институт,   Институт молекулярной биологии РАН им. В.А. Энгельгардта,   НИЦ «Курчатовский институт» - ГосНИИгенетика
Published: October 2020

The MinION system (Oxford Nanopore Technologies Limited) was used for direct sequencing of genomic DNA of two recombinant E. coli strains. In one case, the cells contained a plasmid with the M.HpaII gene of DNA methyltransferase, which methylates the second cytosine in CCGG site; in the second case, the E. coli strain contained M.HspAI DNA methyltransferase, which modifies the central cytosine in the GCGC sequence. In both cases, DNA methyltransferases methylate cytosine to 5-methylcytosine. It has been shown that when DNA is sequenced at high coverage, the presence of 5-methylcytosine in DNA can be detected with high accuracy. In particular, in E. coli DNA containing the cloned gene of DNA methyltransferase M.HspAI, at 1300coverage, 98.9% of the GCGC sites are identified as methylated at the first cytosine. At the same time, only 0.09% of the remaining tetranucleotides, which have the CpG dinucleotide in the middle, give a false positive result being identified as methylated at the central cytosine...
ЭЛЕКТРОСТАТИЧЕСКОЕ ВЗАИМОДЕЙСТВИЕ ГЛОБИНОВ С ФОСФОЛИПИДНЫМИ МЕМБРАНАМИ
Authors:   Институт биофизики клетки РАН - обособленное подразделение ФИЦ «Пущинский научный центр биологических исследований РАН», Постникова Г.Б. , Шеховцова Е.А. ,   Институт биофизики клетки РАН - обособленное подразделение ФИЦ «Пущинский научный центр биологических исследований РАН», Сивожелезов В.С. ,   Институт биофизики клетки РАН - обособленное подразделение ФИЦ «Пущинский научный центр биологических исследований РАН»
Published: October 2020

The present study aimed to analyze the role of electrostatic interactions contributing to the stability of the native conformations of the heme group in the structure of sperm whale myoglobin (SWMb), horse heart myoglobin (HHMb), hemoglobin I (HbI) from the botfly Gasterophilus intestinalis (giHbI) and monomeric and dimeric hemoglobins HbI and HbII from the mollusk Lucina pectinata (lpHbI and lpHbII) as well as investigate a possible reason of destabilization due to interaction with negatively charged phospholipid membranes. It was shown that the native conformation of the heme cavity in these globins, both in its proximal and distal sides, is sustained by a system of hydrogen bonds involving the proximal and distal protein residues, both heme propionic acid groups and the nearby polar amino acids on the protein surface (His, Arg, Lys). The hydrogen bond network in the proximal part of the heme pocket controls the position of the Fe atom outside or in the protoporphyrin plane, affecting the efficiency of ligand binding, while in the distal part of the heme cavity the hydrogen bond network formed with the participation of the distal protein residue (HisE7 in swMb, hhMb and giHbI, and GlnE7 in lpHbII) should, apparently, stabilize conformation where the protein is able to donate hydrogen to O2 ligand...
ЦИТОТОКСИЧЕСКОЕ ДЕЙСТВИЕ ПОЛИАКРИЛАТА ЗОЛОТА (АУРУМАКРИЛ) НА ФИБРОБЛАСТЫ КОЖИ ЧЕЛОВЕКА
Authors:   Институт биохимической физики им. Н.М. Эмануэля РАН, Корман Д.Б. , Некрасова Е.И. ,   Институт биохимической физики им. Н.М. Эмануэля РАН, Островская Л.А. ,   Институт биохимической физики им. Н.М. Эмануэля РАН, Рябая О.О. ,   Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина Минздрава России, Блюхтерова Н.В. ,   Институт биохимической физики им. Н.М. Эмануэля РАН, Абзаева К.А. ,   Иркутский институт химии им. А.Е. Фаворского Сибирского отделения РАН
Published: October 2020

The cytotoxic effect of the potential antitumor drug aurumacryl (aurum polyacrylate) on the hFB-hTERT6 human skin fibroblast cell line has been studied in vitro. It has been established that aurumacril exhibits substantial cytotoxicity to human skin fibroblasts. The maximum of cytotoxic effect (75% cell death) was observed when the concentration of aurumacryl was 0.125 mg/ml. The inhibitory concentration of aurumacryl causing 50% human skin fibroblast death (IC50) was 0.09 mg/ml.
ОСОБЕННОСТИ БИОФИЗИЧЕСКИХ СВОЙСТВ ФОРМЕННЫХ ЭЛЕМЕНТОВ КРОВИ ЛЮДЕЙ ПОЖИЛОГО ВОЗРАСТА В УСЛОВИЯХ МЕХАНИЧЕСКОГО СТРЕССА IN VITRO
Authors:   Белгородский национальный исследовательский университет, Сладкова Е.А. , Скоркина М.Ю. ,   Белгородский национальный исследовательский университет
Published: October 2020

This study explores the peculiarities of biophysical properties in blood cells of the elderly under mechanical stress, applied in vitro, which, according to the literature data, triggers the signaling pathways engaged by purinergic receptor activation. Along with it, we detected a decrease in the stiffness of the cell surface of red blood cells, granulocytes, lymphocytes and platelets and the surface potential became more positive. Our findings could increase knowledge about the effect of mechanical deformation on leukocytes and platelets, which are the main regulators of homeostatic processes in the microvasculature, and on red blood cells involved in the regulation of vascular tone of arterioles and tissue oxygenation in the elderly.
ОСОБЕННОСТИ ОТВЕТНОЙ РЕАКЦИИ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ НА ГЕОМАГНИТНУЮ ВОЗМУЩЕННОСТЬ НА РАЗЛИЧНЫХ ШИРОТАХ
Authors:   Саратовский государственный медицинский университет им. В.И. Разумовского, Паршина С.С. , Самсонов С.Н. ,   Институт космофизических исследований и аэрономии им. Ю.Г. Шафера Якутского научного центра СО РАН, Афанасьева Т.Н. ,   Саратовский государственный медицинский университет им. В.И. Разумовского, Петрова П.Г. ,   Медицинский институт Северо-Восточного федерального университета им. М.К. Аммосова, Стрекаловская А.А. ,   Медицинский институт Северо-Восточного федерального университета им. М.К. Аммосова, Петрова В.Д. ,   Саратовский государственный медицинский университет им. В.И. Разумовского, Кодочигова А.И. ,   Саратовский государственный медицинский университет им. В.И. Разумовского, Комзин К.В. ,   Медицинский институт Северо-Восточного федерального университета им. М.К. Аммосова, Токаева Л.К. ,   Саратовский государственный медицинский университет им. В.И. Разумовского
Published: October 2020

This paper describes the principles of multi-latitude monitoring “Heliomed-2” conducted for obtaining new data on the impact of space weather on human health. The paper presents results of synchronous monitoring oriented to the assessment of the response of the cardiovascular system and psycho-emotional state of healthy volunteers to changes in the geomagnetic disturbance at high (Tixie settlement and the city of Yakutsk) and middle (city of Saratov) latitudes. In all the volunteers, the effects of synchronization of ventricular myocardial repolarization processes (according to the data on the symmetry coefficient of the T wave of the electrocardiogram) and geomagnetic disturbance as well as synchronization of reactive anxiety and geomagnetic disturbance were observed. It has been established that regardless of latitude, cardiac sensitivity and psychological sensitivity to geomagnetic disturbances in volunteers from the same group were similar.
О КАЛИБРОВКЕ АВТОНОМНОЙ МОДЕЛИ ТУНДРОВОЙ БИОЛОГИЧЕСКОЙ ПОПУЛЯЦИИ ЛЕММИНГОВ
Authors:   Вычислительный центр им. А.А. Дородницына Федерального исследовательского центра «Информатика и управление» РАН, Каменев Г.К. , Саранча Д.А. ,   Вычислительный центр им. А.А. Дородницына Федерального исследовательского центра «Информатика и управление» РАН, Поляновский В.О. ,   Институт молекулярной биологии им. В.А. Энгельгардта РАН
Published: October 2020

The paper presents an autonomous model of the biological population of lemmings of a phenomenological type, designed in complex studies of tundra communities. In the model, the dynamics of a population is described through a difference equation relating the population in two neighboring years that depends on three parameters of the biological and ecological genesis. The combination of parameter values included in the equation under consideration determines a class of one-dimensional unimodal mappings of a dynamical system in which the bifurcation properties, asymptotics, and stability of trajectories were analytically and numerically studied. In this paper the main focus is made on model identification criterion. The method of identification sets is proposed to be used for calibration of the model. The identification sets method is based on the approximation and visualization of small-dimensional projections of a multidimensional graph of the error function given in the space of three environmental and two population parameters. This paper describes a case study of model identification using data on the tundra lemming population on the Taimyr Peninsula. It is shown that in this case two biological and ecological parameters allow for stable location distribution.
ВЛИЯНИЕ ОБЕДНЕННОГО ДЕЙТЕРИЕМ ПИТЬЕВОГО РАЦИОНА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЦЕНТРАЛЬНОЙ НЕРВНОЙ СИСТЕМЫ ЖИВОТНЫХ В УСЛОВИИ ГИПОКСИИ
Authors:   Кубанский государственный университет, Козин С.В. ,   Южный научный центр РАН, Кравцов А.А. ,   Южный научный центр РАН, Злищева Э.И. ,   Кубанский государственный университет, Шурыгина Л.В. ,   Кубанский государственный университет, Малышко В.В. ,   Южный научный центр РАН,   Кубанский государственный медицинский университет Минздрава России, Моисеев А.В. ,   Кубанский государственный аграрный университет, Елкина А.А. ,   Кубанский государственный университет,   Южный научный центр РАН, Барышев М.Г. ,   Южный научный центр РАН
Published: October 2020

The effects of prolonged (42 days) addition of deuterium-depleted water into rat’s diet on the functional state of the central nervous system in normal conditions and under conditions of normobaric hypoxia with hypercapnia were studied. It was also established that the use of deuterium-depleted water both in normal conditions and after exposure to oxidative stress contributes to a significant reduction in the emotional anxiety of animals. Prolonged use of deuterium-depleted water before hypoxic exposure (amnestic effect) helps to maintain learning and memory at the control level, i.e. it has a pronounced protective antiamnestic effect. In normal conditions, deuterium-depleted water does not affect the learning ability of animals.
Determination of the magnetic moments of 6Li and 7Li nuclei using an NMR spectrometer that records signals from two nuclei simultaneously
Authors: Neronov Yu. I.
Published: October 2020

The ratio of NMR frequencies of lithium isotopes was determined: with an error of 4,9·10–10. We used a spectrometer mode with simultaneous recording of signals from two cores, which allows us to reduce random and systematic errors by an order of magnitude. The ratio of the resonant frequencies of water protons and 7Li ions was determined: with an error of 3,5·10–9 for solutions with an extremely low concentration of LiOH*H2O salt in water and at a temperature of 25 °C. Based on the data obtained, the magnetic moments of lithium nuclei were calculated. The known data on the magnetic moment of the proton and data on the electronic shielding of these nuclei were used. The comparison of experimental data on µ(6Li) and µ(7Li) with data from theoretical calculations is discussed.
Heat conductivity of pyrolytic graphite of mark UPV-1 at temperatures 1900–2950 K
Authors: Kostanovskiy А. V. , Kostanovskaya M. E. , Zeodinov M. G. , Pronkin A. A.
Published: October 2020

The urgency of the work is caused by that at research of heat conductivity in anisotropic materials is necessary to consider infringement of parallelism between vectors of heat flux and a gradient of temperature. In the previous works at studying heat conductivity of pyrolytic graphites techniques which were applied to isotropic graphites were used. Results of measurement of heat conductivity of pyrolytic graphite of mark UPV-1 in a direction in parallel to a plane of sedimentation are presented. The experimental samples which are heated up by an electric current, represented hollow cylinders at which the plane of sedimentation of pyrolytic graphite has been located along radius. It is offered also heat flux which defined on energy of radiation from an external surface of the sample, and a gradient of temperature to measure along radius, that is strictly in parallel each other. The comparative analysis of experimental data of heat conductivity (in parallel a plane of sedimentation), measured in the given work and resulted in literature sources is brought. The range of the investigated temperatures makes 1900–2950 K and is expanded in area of higher values on 450 K.
High-temperature spectral thermometry in conditions of intense microwave electromagnetic fields
Authors: Lapshinov B. A. , Mamontov A. V.
Published: October 2020

In this paper, a practical application variant of the high-temperature spectral thermometry method for controlling the temperature of a dielectric object heated in a high-intensity microwave electromagnetic field is proposed. The advantages of using the spectral pyrometry method over the methods of color and brightness pyrometry when registering high temperatures (from 500 °C and above) are described. The optical fiber cable used in this method, which receives thermal radiation from an object heated in the microwave field, is subject to the negative influence of the electromagnetic field, which leads to its unacceptable heating and failure. To eliminate this phenomenon, a non-standard use of an cutoff waveguide placed not outside, but inside the microwave heating chamber is proposed. It is shown that this solution completely eliminates the negative influence of the electromagnetic field on the fiber optic cable and allows placing the receiving end of the cable in close proximity to the object being heated. The calculation of geometric parameters of the cutoff waveguide for the operating frequency of the electromagnetic field of 2450 MHz is given.
The influence of external conditions on sound pressure in the pistonphone at the infrasound frequency range
Authors: Konkov A. V. , Golovin D. V.
Published: October 2020

The influence of environmental conditions on a sound pressure reproduced by the primary method in the measuring chambers of the Pistonphone in the frequency range from 1 mHz to 250 Hz is estimated. Numerical estimations of influence of environmental conditions on sound pressure in pistonphone measuring chambers are given and special requirements to system of maintenance of required external conditions are specified.
Nonlinear parameter estimation by the point-mass method taking into account correlation of partial estimates
Authors: Sholokhov A. V. , Berkovich S. B. , Kotov N. I. , Belonozhko M. G.
Published: October 2020

A new solution to the problem of nonlinear parameter estimation is considered. The peculiarity of this problem is that the arguments of a nonlinear function are not only the measurement data and the required parameters, but also supplementary parameters. Supplementary parameters are a priori unknown, but they are necessary only to find optimal estimates of the required parameters. The estimate of the desired parameters is formed according to the point-mass method as a weighted sum of partial estimates obtained for the specified values of supplementary parameters. This solution allows us to eliminate a priori probabilities for supplementary parameters by taking into account additional covariance of weight coefficients and (or) specified partial estimates. The considered approach is effective in solving specified nonlinear estimation problems characterized by low accuracy of available measurement data and (or) their few number.
Nominative Specificity of English Marketing Terminology
Authors: Rubert I. B. , Rosyanova T. S. , Kiselieva S. V.
Published: October 2020

Introduction. The paper deals with the concepts of a term and terminology as they considered both in classical general theory of terminology and cognitive linguistics. The field of English economic terminology provides extensive material for the terminologists to develop and clarify theoretical guidelines helping to understand the nature of scientific and professional nominations that constitute the aim of presented reseach. The processes of term formation viewed through the cognitive approach are considered in connection with conceptualization and categorization and help to reveal the creative nominative models of marketers as it is seen vital within an antropocentric focus of linguistic studies.

Methodology and sources. A general theory of terminology is based upon the approach in which the nature of concepts, conceptual relations, the relationships between terms and concepts and assigning terms to concepts are of prime importance. But in fact, terminology is closely linked to an activity carried out within the field of knowledge and thus it is inseparable from its social context and its obvious applications. Methods of cognitive analysis applied for the study of terminilogies are supposed to overcome contradictions of the previous century of terminology studies. English marketing terms under consideration were extracted from the professional dictionaries and handbooks. The thematic group chosen as the illustrative example is consumer terminological group.

Results and discussion. Nominative originality of marketing terminology has been revealed within the idea of continually changing specific autonomous and self-sufficient consumer models reflected in micro-systems of terms nominating and verbalizing holistic concepts of the authors. Nomination of the typical individuals (customers) by the terms discussed in the presented paper reflects deep and various psychological characteristics of individuals. As it seems, all these parameters form the foundation of the professional domain of modern markets in accordance with the existing conceptual knowledge, verbalized by terms.

Conclusion. The study is relevant since the research of conceptualization and categorization in the professional fields of knowledge seems to be an understudied area. The more interdisciplinary is the area of professional knowledge, the more integrated are specific features of terminological nomination, and the more sophisticated is the termformation used by the experts.
Professional Identity of Journalist in Hybrid Media System
Authors: Kolianov A. Yu.
Published: October 2020

Introduction. This paper analyzes how the journalists’ professional identity is changing in the reality of hybrid media system. Understanding of journalists’ professional identity is based upon the conclusion that information environment is building the journalists’ characters today. The mixing of media and digital technologies leads to the hybridization of media in its basis. Journalist’s activities within the present media system lead to contradictory and sometimes odd effects.

Methodology and sources. The comparison and generalization of expert interviews, public opinion polls and official documents and media texts were applied. Content analyses of journalist’s papers and discourse analysis of theoretical studies were also used to study the professional identity of journalists.

Results and discussion. In this paper we try to answer how does the global digital environment affect the conditions, goals and effects of journalist’s professional activities? How the journalist’s professional activity changes? What characteristics of journalist should be included in the professional identity that appears in the hybrid media system? We consider such factors affecting political journalists’ self-identification as recruiting organization and its founders’ proximity to the power structures, pool of experts, party allegiance and journalist’s skills including the level of technological equipment and understanding the modern network principles of the life of information.

Conclusion. Due to the increasing amount of information social uncertainty is rising and it is becoming harder and harder to forecast media impact on the public consciousness. Studies among journalists in Russia, Europe and USA show that professional selfidentification is blurred within personal, professional and virtual roles and results in hybrid identity that sometimes consists of mutually exclusive values. It is possible to suggest that structure changes in professional identity structure will affect the components of professionalism in the future.
Estrategias de bilingüismo en escuelas primarias interculturales bilingües
Authors: Manresa Antonia
Published: October 2020

En septiembre del 2017, en Ecuador, el Ministerio de Educación apoyó un proyecto piloto para la formación de mentores desde la propuesta metodológica del programa Escuelas Lectoras de la Universidad Andina Simón Bolívar. Este proyecto, con una duración de dos años, tenía como objetivo formar aproximadamente 50 docentes preseleccionados para dar acompañamiento a docentes de aula en zonas rurales o urbanas periféricas para mejorar la enseñanza-aprendizaje de lectura y escritura en los primeros grados de Educación Básica. En el marco de este proyecto, se investigó cómo los y las mentores kichwa-hablantes hacen uso del bilingüismo y de qué forma esto favorece el proceso de enseñanza-aprendizaje de lectura y escritura en contextos de bilingüismo. El estudio presenta hallazgos con respecto a tres estrategias de uso del bilingüismo como parte del proceso de enseñanza-aprendizaje de la lectura y la escritura: la traducción literal, el bilingüismo comunicativo y la exclusividad lingüística.
Gerenciamento de farmácia hospitalar: Enfoque logístico na cadeia de suprimentos
Authors: Oliveira Rayanne Alves De , Lima Vinícius Mendes , França Lucielma Cavalcante De Jesus , Silva Lucrécia Pereira
Published: October 2020

O hospital é uma unidade crítica no processo de gestão de forma geral. Essa criticidade se torna mais acentuada quando se refere à logística de suprimentos. Na unidade hospitalar, convém destacar a farmácia hospitalar como um núcleo indispensável para um tratamento eficaz e seguro ao paciente. Objetivo: identificar e relatar as principais dificuldades e ineficiências no processo da gestão de suprimentos em farmácias hospitalares. Metodologia: Revisão literária de artigos indexados nas bases de dados Lilacs, SPELL, Scielo, Medline e Portal de Periódicos CAPES, no período de 2005 a 2019, sobre gestão de suprimentos em farmácias hospitalares. Resultados: foram selecionados 25 artigos, que abordaram a temática, os quais foram estudados criticamente, visando compreender o processo da cadeia de suprimentos nas farmácias hospitalares. Conclusão: a principal dificuldade encontrada foi o controle eficaz dos estoques. Em consequência disso, em dado momento, a falta de alguns materiais e medicamentos, trazendo, portanto, danos ou prejuízos aos pacientes.
Después de la pandemia, el Brexit seguía ahí
Authors: Anchuelo Álvaro , Feás Enrique
Published: October 2020

Este artículo analiza de forma sistemática las negociaciones entre la UE-27 y el Reino Unido para definir su relación futura tras el Brexit. En el ámbito comercial, los compromisos que garanticen una competencia leal y la pesca constituyen las principales dificultades. Los intercambios de servicios, en particular financieros, son otro tema crucial. Respecto a seguridad, defensa, relaciones exteriores y la gobernanza del acuerdo, el Reino Unido opta por marcar distancias.
Transición energética y gobernanza climática en tiempos de pandemia
Authors: Lázaro Touza Lara , Escribano Francés Gonzalo , Crespi de Valldaura Virginia
Published: October 2020

La pandemia del COVID-19 ha alterado las expectativas acerca de la transición energética, acentuando las tendencias subyacentes previas a la misma. La gobernanza climática también se ha visto afectada por el COVID-19 en un año clave para elevar la ambición. Aunque la prioridad de gobiernos y ciudadanos sea la lucha contra el virus, este cambio radical en el contexto a corto plazo no debe distraer de los retos que plantean la transición energética y la gobernanza climática a medio y largo plazo.
L'azione dell'Unione europea
Authors: Fragola Massimo
Published: October 2020

La competenza dell'Unione europea in materia di turismo è una competenza minima e residuale giacché gli Stati membri non hanno espresso, sinora, la volontà politica di trasferirla all'Unione. Per questo motivo può dirsi che l'Unione non abbia una politica comune del turismo. Questo approccio è stato rispettato anche durante la pandemia da coronavirus
L'incidenza della normativa COVID-19 nell'assetto delle competenze Stato-Regioni in materia di turismo
Authors: Nocerino Assunta
Published: October 2020

L'emergenza COVID-19 ha accentuato l'interventismo statale nel settore turistico, tramite un apparato normativo i cui effetti limitativi della competenza legislativa regionale sono destinati a protrarsi nel tempo.
I contratti relativi ad eventi, mostre e spettacoli: vicende e rimedi al tempo del COVID-19
Authors: Cocuccio Mariafrancesca
Published: October 2020

Il contributo approfondisce le problematiche dei contratti relativi ad eventi, mostre e spettacoli nella situazione emergenziale provocata dal COVID-19. Sono state preliminarmente individuate due tipologie di contratti, riferibili la prima (sub A) ai contratti stipulati per l'organizzazione degli eventi, la seconda (sub B) ai contratti stipulati dai fruitori. Si è quindi esaminata la disciplina codicistica, evidenziandone la rigidità e la poca attenzione a opzioni volte alla manutenzione del contratto, e le nuove regole della legislazione emergenziale, al fine di ricostruire il quadro normativo di riferimento, con specifica attenzione ai rimedi esperibili.
I rapporti di lavoro
Authors: Timellini Caterina
Published: October 2020

Lo scritto analizza le misure di emergenza introdotte dal Governo a sostegno del lavoro, quali gli speciali ammortizzatori sociali e la sospensione dei licenziamenti, soffermandosi sull'interpretazione e sui limiti di esse.