bluuebunny/crossref_metadata_2025 huggingface dataset:
MODULATION OF OXIDATIVE STRESS BY ABHRAK BHASMA IN DROSOPHILA MELANOGASTER
Authors: Subedi Rambhadur P , Vartak Rekha R , Kale Purushottam G
Published: May 2018

Objective: Management of aging is one of the most actively researched areas in biology. Ayurvedic preparations such as Abhrak Bhasma (AB) have been used for improving longevity and regenerative therapy as well as in treating various ailments. Modes of action of such Ayurvedic preparations are poorly understood at molecular level. Current investigation tests the efficacy of AB in modulating various parameters linked to oxidative stress.Methods: Drosophila melanogaster was used as a model system to test the efficacy of AB in inducing antioxidant machinery. Drosophila flies were fed on diet supplemented with AB at larval and adult stages. Subsequently, various parameters, catalytic as well as non-catalytic, related to antioxidant machinery were analyzed.Results: AB has been found to modulate the activity of superoxide dismutase and catalase enzymes as well as the total reduced glutathione (GSH) content. Larvae and adults feeding on diet supplemented with AB exhibit significantly lower levels of total GSH content (decrease of about 40–70% for larvae, while 31–36% for adults) and without any conclusive effect on GSH:oxidized glutathione ratio, free radical scavenging capacity, and extent of lipid peroxidation. These larvae and adults fed on diet supplemented with AB also exhibited an increase in the level of transcription of cap “n” collar C, heat shock protein 70, and catalase genes (≥1.5 fold, except in few cases).Conclusion: Overall, AB alters various parameters linked to antioxidant machinery in D. melanogaster. The induced components may provide protection to the organism during stressful conditions.
CORRELATION OF OXIDATIVE STRESS MARKERS MALONDIALDEHYDE (MDA), ANTIOXIDANT VITAMINS A, E, AND C WITH GLYCATED HEMOGLOBIN (HBA1C) LEVELS IN TYPE 2 DIABETES MELLITUS
Authors: Altoum Abd Elgadir A. , Osman Ahmed L. , Babker Asaad Ma.
Published: May 2018

Objective: The purpose of this study was to understand the relationship between oxidative stress markers malondialdehyde (MDA), antioxidant Vitamins A, E, and C and the glycated hemoglobin levels with Type 2 diabetes mellitus. Methods: The current study is a cross-sectional study group, comprised no diabetic individuals (100 healthy) as control groups and diabetic patients (300) as cases groups, attending the Khartoum - Sudan for routine follow-up during 2013–2015. The data were collected with the help of structured questionnaire and direct interview to collect information. Blood specimens were collected from both groups, and plasma levels of MDA, serum zinc, antioxidant Vitamins (A, E, and C), and glycated hemoglobin (HbA1c) were determined. Odds ratio and the 95% confidence interval (95% CI) were calculated for the presence of mutation between cases and controls and analyzed by SPSS program, version 13. Results: The results of this study indicate a highly significant difference between the means of HbA1c% of the test group (n=300) and the control group (n=100). Mean ± SD: 7.5 ± 1.4 versus 4.9 ± 0.3, respectively (p=0.001). Significant positive correlation between HbA1c and MDA (p=0.003). Significant correlation between HbA1c% and plasma Vitamins A, E, and C of the test group, respectively (p=0.002), (p=0.0008), and (p=0.01). Conclusion: There was significant correlation between HbA1c% with Malondialdehyde (MDA) and antioxidant Vitamins (A, C, and E).
POLYMERS IN CARDIOVASCULAR SURGERY
Authors: Matarneh Rami , Sotnik Svitlana , Lyashenko Vyacheslav
Published: May 2018

Surgical intervention is still one of the most important treatment methods to investigate or treat a pathological condition, and the cardiovascular surgery is considered one of the most important types of surgical interventions at all. The uniqueness of a human body and the impossibility of its full procreation, enforces the use of various auxiliary materials such as polymers to carry out the most difficult surgery while ensuring further vital activity. In this paper, we explore the features of polymers which are used in cardiovascular surgery, discussing the existing variety of such polymers and the orientations of their use. Depending on the carried out analysis, the classification of main types of polymers had been offered which are the most suitable for cardiovascular surgery, besides generalized classification of polymeric products defects. The obtained results enable to immediately identify all significant factors that may lead to emergence defect for the purpose of its control and prevention to improve the quality of surgical intervention and stabilize the patient’s cardiovascular system.
SHORT TIME RESULT OF PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY ON ISCHEMIA DIABETIC FOOT ULCER
Authors: Irawan Hendry , Mooy Danny Zefanya , Yasa Ketut Putu
Published: May 2018

The frequent complication of diabetes mellitus is ischemic diabetic foot ulcers (DFUs). As compared to non-diabetic people, ischemic of foot prevalence is significantly higher in diabetic people. It is related with severe clinical manifestations and the risk of critical limb ischemia and limb loss is increasing. In this case, we performed percutaneous transluminal angioplasty (PTA) in patient with ischemic DFU. A male, 58-year old, complained severe rest pain and gangrene in the fourth toe of the left foot more than 2 months. He had a history of diabetes mellitus type 2 for 4 years ago with uncontrolled blood sugar. We perform PTA to decrease the rest pain and prevent expand of the gangrene. The result of PTA was shown instant effect to reduce rest pain, pulses are easily palpable, and there was no expansion of the gangrene.
INVESTIGATING EFFECT OF NURSING INTERVENTIONS, BASED ON WELLS SCORE RESULTS, ON THE INCIDENCE OF DEEP VEIN THROMBOSIS IN PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT
Authors: Habibi Moghadam Morteza , Asadizaker Marzieh , Jahani Simin , Maraghi Elham , Saadatifar Hakimeh , Naanaei Farhad
Published: May 2018

Objective: Venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common complaint in critically ill patients. Therefore, the present study was conducted to determine the effect of nursing interventions, based on the Wells results, on the incidence of DVT in intensive care unit (ICU) patients.Methods: The present clinical trial was conducted on 72 ICU patients without DVT and PE who met the inclusion criteria according to Wells score in Dr. Ganjavian Hospital, Dezful in 2012. The participants were investigated and randomly divided into intervention (n=36) and control groups (n=36). The intervention group received preventive nursing measures based on the risk level determined by the Wells score, and routine therapeutic interventions were performed for the control group. Then, patients were evaluated using Wells score, D-dimer testing, and Doppler sonography on the 1st, 5th, and 10th days. Data were finally coded and entered into SPSS version 23. Data analysis was performed using Chi-square, Fisher’s exact, and Mann–Whitney U tests.Results: The incidence of DVT in both groups showed that 2 patients of the control group who were identified to be at risk using the Wells score were diagnosed with DVT while none of the patients of the intervention group experienced DVT. The present study showed that 22.2% of the patients of the control group suffered from non-pitting edema, which was significantly different from the intervention group (p=0.005).Conclusion: The results of the present study showed that using the Wells score for early identification of the at-risk patients and nursing interventions based on this score’s results is helpful in the prevention of DVT. Appropriate nursing interventions were also effective in reducing the incidence of non-pitting edema in the lower extremities.
IN VITRO ANTI-INFLAMMATORY ACTIVITY OF BLUE-GREEN ALGAE-GEITLERINEMA SPLENDIDUM COLLECTED FROM WESTERN GHATS, SOUTH INDIA
Authors: J Krishnaveni , Mangai S Alarmal , Jency I Mary
Published: May 2018

Objective: Geitlerinema splendidum is non-edible blue-green algae available in freshwater systems. It belongs to the family Pseudanabaenacae genera. In exploring the medical properties of algae, our present work aimed to analyze the anti-inflammatory effect of the algae G. Splendidum.Methods: Anti-inflammatory activity was done by human red blood cell membrane stabilization assay for ethyl acetate and ethanol crude extracts of alga and found that the ethyl acetate extract has better inhibitory property than ethanol crude extract. Diclofenac was used as the standard drug.Results: The experimental results obtained are comparable to the reference drug and are found to be dose-dependent. Even at a minimum concentration of 12.5 μg/ml, the percentage inhibition was in the range of 56.6±0.12–58.5±0.03 %, which indicated that the alga G. splendidum has a satisfactory anti-inflammatory activity.Conclusion: Our present work is supposed to be the first report in exploring the anti-inflammatory effect of the algae G. splendidum.
DEVELOPMENT AND VALIDATION OF THE REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE ESTIMATION OF GUAIFENESIN IN METHOCARBAMOL API AND ITS PHARMACEUTICAL DOSAGE FORMS
Authors: Durga Babu Mannem , Surendrababu Kesana
Published: May 2018

Objective: The objective of the study was to develop and validate a novel, specific, precise, and simple reversed-phase high-performance liquid chromatography method for the estimation of guaifenesin present in methocarbamol API and its pharmaceutical dosage forms. Methods: The baseline separation for methocarbamol and guaifenesin was achieved by utilizing a Inertsil ODS C18 (250 mm × 4.6 mm) 5 μm column particle size and an isocratic elution method. The mobile phase contains a mixture of water and acetonitrile in the ratio of 70:30 v/v, respectively. The flow rate of the mobile phase was 1.0 mL/min with a column temperature of 25°C and detection wavelength at 272 nm. The method was validated for a limit of detection (LOD), limit of quantification (LOQ), linearity, accuracy, and reproducibility with the help of the exhibit and simulated samples. Results: The LOD for guaifenesin was 0.62 μg/mL. The LOQ for guaifenesin was 1.87 μg/mL. The correlation coefficient obtained for impurity was >0.99. The recovery was obtained for impurity was 106.56% at 50%, 95.20% at 100%, and 100.45% at 150%. In tablet analysis, we can found 0.26% (<0.5%). Conclusion: The developed method was validated as per the ICH guidelines with respect to specificity, precision, linearity, accuracy, LOD and quantification, ruggedness, robustness, and solution stability.
EFFECT OF ETHANOLIC FLOWER EXTRACT OF SPATHODEA CAMPANULATA ON STREPTOZOTOCIN INDUCED DIABETIC NEUROPATHY
Authors: Bachhav Rishikesh , Saudagar Ravindranath
Published: May 2018

Objective: To evaluate the effect of ethanolic extract of the flower of Spathodea camapanulata (EFESC) on streptozotocin-induced diabetic neuropathy.Methods: Non-insulin dependent diabetes mellitus (NIDDM) was induced in overnight fasted adult wistar strain albino male rats weighing 160-200g by a single intraperitoneal injection (i. p) of streptozotocin (STZ-65 mg/kg). The rats were randomized into six groups, with six animals each, namely normal control (NC) (Treated with 1% carboxymethyl cellulose solution), diabetic control (DC) (65 mg/kg., i. p. STZ), test group treated at various doses of EFESC250, EFESC500, and EFESC750, standard control-glibenclamide0.25 mg/kg b.w.(SCG) and the treatment has begun from the day of blood sugar level (BSL) detection after the STZ treatment. Body weight was checked daily and serum glucose levels were measured at 48 h, 15th and 28th d of study. Reaction time to thermal hyperalgesia and cold allodynia were measured after induction of diabetes. In vitro, aldose reductase inhibition assay was carried out.Results: The preliminary phytochemical screening revealed the steroids, terpenoids, coumarins, carbohydrates, tannins, glycosides, and flavonoids in EFESC. DC group showed decreased in reaction time (hyperalgesia) compared to NC while a significant increase in reaction time was observed at various doses EFESC250, EFESC500, EFESC750 and SCG0.25. EFESC at various doses showed the significant reduction in BSL and body weight on 15th and 28th d in STZ diabetic rat at various dose levels. In vitro, aldose reductase inhibition was observed with an IC50 at 131 μg/ml.Conclusion: EFESC showed reduced in BSL and prevents hyperalgesia in experimental diabetic neuropathy. It also reduced aldose-reductase level that may play an important role in reducing the complication of diabetic neuropathy.
ANTIMOTILITY AND ANTISECRETORY RELATED ANTIDIARRHOEAL ACTIVITY OF THE ABELMOSCHUS MOSCHATUS MEDIK IN EXPERIMENTAL ANIMAL MODELS
Authors: S. Babitha , Hg Akshay Deepu , Taj Nageena
Published: May 2018

Objective: This study was intended to evaluate the anti-diarrhoeal potential of Abelmoschus moschatus Medik (A. moschatus Medik) seeds and the possible mechanism therein involved by using different experimental models in albino Wistar rats.Methods: The hydroalcoholic seed extract of A. moschatus Medik. (HEAM) was orally administered at the doses of 150, 300 and 500 mg/kg respectively to the different groups in order to assess the effect of extract in castor oil induced diarrhea model in rats. In order to comprehend the mechanism involved in its anti-diarrhoeal potential, the extract was further investigated for its effect on gastrointestinal motility using charcoal meal test and antisecretory action by castor oil induced intestinal enter pooling where, atropine sulphate (5 mg/kg) and loperamide (2 mg/kg) were used as reference standards respectively.Results: The HEAM exhibited significant (p<0.05, p<0.001) and dose-dependent anti-diarrhoeal effect by decreasing the mean number of fecal droppings produced upon castor oil administration as compared to the normal control. The effect of the extract at 500 mg/kg was near to that of loperamide (2 mg/kg). The extract (300 mg/kg) showed antimotility action by significantly (p<0.05, p<0.001) attenuating the charcoal meal transit in the intestine as compared to negative control animals. Further, the extract showed significant (p<0.05, p<0.001) inhibition in the accumulation of intestinal fluid due to castor oil.Conclusion: The HEAM exhibited significant anti-diarrhoeal action that could be presumably related to its observed antimotility and antisecretory activities. This study justifies the usage of A. moschatus Medik. as an anti-diarrhoeal agent in traditional practices of medicine.
HPTLC METHOD FOR THE DETERMINATION OF LUPEOL FROM ANDROGRAPHIS ECHIOIDES LEAVES
Authors: Gurupriya S. , Cathrine L. , Pratheema P.
Published: May 2018

Objective: A new simple, precise, rapid and selective high‐performance thin‐layer chromatographic (HPTLC) method has been developed for the determination of lupeol in methanolic leaves extract of Andrographis echioides.Methods: As per International Conference on Harmonization (ICH) guidelines we have applied different concentrations of lupeol as standard on HPTLC plates for the quantification of lupeol from the Andrographis echioides leaves. The concentration of standard lupeol was 1 mg/ml.Results: The retention factor of lupeol was found to be 0.55. Linearity was obtained in the range of 5000 ng‐10000 ng for lupeol. The developed and validated HPTLC method was employed for lupeol in methanolic leaves extract of Andrographis echioides for standardization of the content of the marker. The linear regression data for the calibration plots showed a good linear relationship with r=0.99917 for lupeol. Satisfactory recoveries of 99.80 % were obtained for lupeol.Conclusion: The results obtained in validation assays indicate the accuracy and reliability of the developed HPTLC method for the quantification of lupeol in methanolic leaves extract of Andrographis echioides.
ASSESSMENT OF SECONDARY METABOLITES WITH RELATION TO THEIR ANTIOXIDANT ACTIVITY OF FUNGAL ENDOPHYTES ISOLATED FROM MEDICINAL PLANTS
Authors: Chowdhury Debjani Roy , Chatterjee Swapan Kumar , Roy Subhash Kanti
Published: May 2018

Objective: The detection of fungal endophytes and assessment of their antioxidant activity isolated from two medicinally important plants, Calotropis procera (L.) R. Br. and Catharanthus roseus (L.) G. Don. from parts of Burdwan district of West Bengal, India.Methods: Isolation of fungal endophytes was carried out following the standard methods in potato dextrose agar (PDA) media. Identification, determination of colonization frequency, fermentation and extraction was done as stated in the standard protocol. Qualitative assay of the bioactive compound has investigated by standard protocol specifically for them. Quantitative estimation of total phenol was done by spectrophotometric method using gallic acid as standard. The antioxidant activity of the cell-free extract was determined by phosphomolybdenum assay and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) scavenging method.Results: Three dominant endophytic fungi each from C. procera and C. roseus with high colonization frequency in Penicillium singorense 25% and Alternaria alternata 21.87 % respectively has isolated and identified. Qualitative detection of secondary metabolites revealed that Penicillium singorense isolated from both plants and Aspergillus neoflaviceps (from C. procera) were found to be able to produce all the functional metabolites so far tested. It is evident that highest phenol 27.65±1.2 mg/g and flavonoid 2.06±0.1 mg/g content was shown by Curvularia geniculata. Highest antioxidant activity was exhibited by C. geniculata in both phosphomolybdenum assay i.e., total antioxidant capacity 2.46±0.11 and % inhibition of DPPH radical 94.55±0.015%.Conclusion: Present study, therefore highlights the growing concept that the bioactive compounds produced by the endophytes not only established host endophyte relationship but also have an immense chance of an application in the field of medicine, agriculture and industry.
COMUNICACIÓN Y AMBIENTES DE APRENDIZAJE “UNA ESTRATEGIA PARA MEJORAR LOS DESEMPEÑOS EN EL AULA”
Authors: Cruz Claudia Yaneth , Reyes González Pedro , Barón Pereira Nancy
Published: May 2018

La comunicación y los ambientes de aprendizaje se constituyen como pilares fundamentales para la construcción del conocimiento de los estudiantes. Bajo este precepto, el artículo da cuenta de un trabajo de intervención que tuvo como finalidad fortalecer las prácticas pedagógicas a través de la construcción de ambientes de aprendizaje, donde la comunicación entre los estudiantes, docentes y padres de familia se convierte en el reactor del desarrollo de los procesos pedagógicos. Metodológicamente, el proceso siguió los principios de la Investigación Acción, basada en la teoría de Elliott (2005). Las técnicas e instrumentos para el diagnóstico, recolección y análisis de los datos fueron: encuesta semiestructurada, talleres y el diario de campo. Las categorías de análisis teóricas, de acuerdo con la naturaleza del proceso de intervención educativa (comunicación, educación en la escuela rural, ambientes pedagógicos), se abordan desde los postulados de autores como Sarramona (1988), Freire (1973), Skliar (2009) y Mejía (2011), concluyendo que la comunicación es un factor fundamental en el desarrollo del ser humano y que obtiene el carácter de determinante en los procesos de enseñanza y aprendizaje.
How can the efficiency of corporate governance in Serbian state-owned enterprises be increased?
Authors: Aleksic-Miric Ana , Todorovic Miroslav , Janicijevic Nebojsa
Published: May 2018

This paper focuses on the practical coexistence of agency and stewardship
theories. By analysing the three dimensions of government structures,
compensation schemes, and monitoring activities, we show that this
coexistence is possible due to several situational factors. Using field
research data, we examine the causes of this coexistence and the effects it
has on the efficiency and effectiveness of corporate governance, and
question the practical sustainability of this dualism. We conclude that
coexistence is possible but is unsustainable, and it would be wrong to
support such a situation for a long period of time. We discuss paths of
potential action and their implications for key stakeholders.
Different understanding of state power as a key notion within the realist theoretical approach
Authors: Lipovac Milan
Published: May 2018

The concept of power is not a new phenomenon, so the intellectual origin of
this concept can also be found among the ancient philosophers. However, the
reconsideration of this concept within the International relations and
Security studies started 60-70 years ago. The representatives of the
realistic theoretical approach were mostly those who dealt with the concept
of power of the state, as well as representatives of other theoretical
approaches (e.g. liberalism, social constructivism, critical theories,
feminist approaches, etc.). But, despite the great interest in this concept,
consensus exists only on two key issues related to power of the state. First,
in the terms of importance everyone agrees that the power of the state is one
of the key concepts, and second, in the terms of complexity. Therefore, no
one should be surprised by the pluralism of viewpoints regarding the concept.
Those viewpoints could be reduced on three prevailing comprehensions of power
of the state: power as control over resources, power as control over actors
and power as control over events and outcomes. All these prevailing
comprehensions have its own advantages and disadvantages. The aim of this
paper was to present the views of relevant scholars (through the theoretical
discussion not only by the realists), and to offer an adequate overview of
the advantages and disadvantages of each of these comprehensions. Such a
review of literature could certainly be useful for researchers in the case of
selecting an adequate comprehension of power of the state for their
particular specific research. The researcher should make this kind of
decision based on a particular school of thought that he/she prefers, his/her
personal affinities, but primarily based on the object and purpose of his/her
research. The conclusion of the paper could be reduced to the notion that the
concept of power of the state is far beyond the scope of realistic
theoretical approach, and that it represents a key concept (and according to
some scholars it is the most important concept in the IR), as well as that
each of these prevailing comprehensions of power of the state has its own
place in the theoretical conceptual apparatus of International relations and
Security studies.
Páginas preliminares
Authors: Preliminares Páginas
Published: May 2018

Páginas preliminares, Revista EIA
Editorial
Authors: Colares Anselmo Alencar , Colares Maria Lília Imbiriba Sousa
Published: May 2018

Nesta edição da Revista Exitus, as contribuições nacionais são oriundas de pesquisas desenvolvidas nos Estados do Pará, São Paulo, Tocantins, Rondônia, Maranhão, Rio Grande do Sul, Bahia, Goiás, Mato Grosso e Alagoas. A experiência internacional está contemplada no artigo PERCEÇÃO, EXPRESSÃO E VALORIZAÇÃO DAS EMOÇÕES DAS CRIANÇAS NA EDUCAÇÃO PRÉ-ESCOLAR de uma pesquisadora da Universidade de Cádis, Espanha.    O número inicia com uma conferência sobre o Projeto Escola Sem Partido. Um assunto polêmico e muito pertinente na atual conjuntura. Os dois textos seguintes tratam sobre a temática na área de políticas educacionais. Sete artigos focalizam as concepções e práticas docentes, e os últimos cinco artigos estão relacionados a outros temas em educação. A edição finaliza com uma resenha apresentando a discussão sobre a Exclusão ou inclusão, problematizando essas terminologias. Na sequência, o leitor terá acesso a uma visão panorâmica do conteúdo integrante deste número, cujo objetivo é o de apresentar algumas possibilidades de trilhas a serem percorridas por todos os que desejam desfrutar de reflexões atuais e significativas para a compreensão do fenômeno educacional. Percurso este acompanhado de estudiosos que estão imersos nos temas e objetos selecionados para suas pesquisas no campo educacional.
Escola sem partido: projeto sem sustância
Authors: Assis Ana Elisa Spaolonzi Queiroz
Published: May 2018

No ano de 2017 tive a oportunidade de discutir o Projeto Escola Sem Partido em cinco ocasiões. A primeira foi durante a Semana da Ação Mundial (SAM), organizada pela “Campanha Nacional pelo Direito à Educação” com apoio da Faculdade de Educação da Universidade Estadual de Campinas (FE/UNICAMP) e do Grupo de Estudos e Pesquisas em Política Educacional (GREPPE) coordenado pela Profª. Drª. Theresa Adrião. Reunidos os Profs. Drs. Daniel Cara (Coordenador da Campanha Nacional pelo Direito à Educação), Wencesláo Machado de Oliveira Júnior (professor da FE/UNICAMP e membro, à época, do Conselho Municipal de Educação de Campinas) e eu em mesa intitulada “Direito Humano à Educação e Respeito à Diversidade: Sobre a Mordaça na e da Escola”, parti do pressuposto de que, no Brasil, a SAM não pode discutir rumos ao desenvolvimento sustentável, vinculado à efetivação plena do direito a educação, sem priorizar a democracia como valor imprescindível destes espaços de atuação e formação.
Estudantes cotistas negros e ações afirmativas no ensino superior
Authors: Eugenio Benedito Gonçalves , Algarra Julia
Published: May 2018

Neste trabalho, analisamos o percurso de escolarização de estudantes negros dos meios populares que ingressaram no ensino superior por meio da política de ações afirmativas. Foram entrevistados 4 estudantes cotistas negros do curso de Direito da Universidade Estadual do Sudoeste da Bahia-UESB. A pesquisa é qualitativa, do tipo exploratória. O estudo realizado nos permitiu compreender como constituiu-se o processo de educação de estudantes negros até a chegada ao Ensino Superior, bem como sua percepção acerca da escolarização e da vivência do racismo. Palavras-chave: Acesso e Permanência. Estudantes Negros. Ensino Superior.
Marx e a politecnia, ou: do princípio educativo ao princípio pedagógico
Authors: Maciel Antônio Carlos
Published: May 2018

Este artigo tem por objetivo expor a trajetória epistemológica da definição do conceito de politecnia como princípio pedagógico e explicar porque é o fundamento determinante da educação integral politécnica. Analisa a concepção marxiana de educação comparando as versões em língua francesa, inglesa, portuguesa e brasileira (MARX, 1976, 1982, 1983, 1996), bem como algumas das mais importantes obras brasileiras sobre o tema (SAVIANI, 1989, 2003, 2007; KUENZER, 1989, 2005; FRIGOTTO, 2002, 2012; SOARES, 2000, 2004; LOMBARDI, 2008; SANFELICE, 1991; NOGUEIRA, 1990; NOSELLA, 2004, 2007, 2009), passando por Manacorda (2010) para demonstrar a importância, mas, ao mesmo tempo, os limites do conceito de trabalho como princípio educativo. O resultado do estudo aponta para a necessidade de: a) atualizar a concepção marxiana de educação; b) complementar o trabalho como princípio educativo com a politecnia como princípio pedagógico; c) operacionalizar a prática pedagógica pela formulação da politecnia como princípio pedagógico; d) demonstrar a educação integral politécnica, da educação infantil à universidade, como alternativa às propostas pedagógicas de educação escolar estatal. Palavras-chave: Politecnia. Princípio Educativo. Princípio Pedagógico.
O protagonismo do coordenador pedagógico na formação docente: experiência na Educação Infantil em Ji-Paraná-RO
Authors: Da Silva Helen Maciel , Machado Ednéia Maria Azevedo , Pacífico Juracy Machado
Published: May 2018

O estudo é resultado de observações feitas ao longo da execução do projeto de extensão da Universidade Federal de Rondônia em parceria com o município de Ji-Paraná/RO, no período de 2015 a 2017. Apresenta uma reflexão sobre o processo e o impacto dos resultados da formação continuada realizada com coordenadores pedagógicos e professores que atuam na Educação Infantil no Município de Ji-Paraná-RO. A metodologia utilizada foi análise dos registros dos encontros de formação, a avaliação final, bem como a observação da participação e dos relatos feitos pelas coordenadoras no espaço de formação. Os sujeitos da pesquisa foram quatorze coordenadoras pedagógicas que atuam na rede municipal. Utilizou-se como referencial teórico as contribuições de Alarcão (2001), Scarpa (1998), Hoffmann (2012), entre outros. Destaca a importância da implementação de um projeto de formação específico para os profissionais da Educação Infantil, bem como discute os caminhos percorridos neste processo no município de Ji-Paraná/RO. Os resultados apontam que a formação continuada para o coordenador pedagógico é de extrema importância, pois ele é o profissional responsável pela formação continuada dos professores no espaço escolar, bem como aquele que possibilita a qualidade das atividades pedagógicas. Palavras-chave: Coordenador Pedagógico. Formação. Educação Infantil.
Experiência pedagógica de professores Karaywa na aldeia indígena Mapuera, Oriximiná-PA
Authors: Coelho Ana Cely de Sousa , Da Silva Messias Furtado
Published: May 2018

Educação escolar indígena consubstanciada em diálogo intercultural que respeite o jeito de ser e viver de cada povo, apesar de garantida nos marcos legais, ainda é uma realidade a ser construído por muitas maõs. Neste artigo, apresentamos resultado de pesquisa sobre a experiência pedagógica de professores não-indígenas na educação escolar do povo indígena Wai-Wai da aldeia Mapuera, município de Oriximiná/PA, com o objetivo de analisar as relações, diálogos e dificuldades enfrentadas por estes na efetivação da educação intercultural em aldeia indígena. A constituição dos dados ocorreu por meio de entrevista semiestruturada com professores que atuam no ensino fundamental da Escola Indígena Mapuera. Os resultados mostram desafios, entraves, dificuldades e potencialidades em efetivar a educação intercultural, instrumento de luta dos povos indígenas pela preservação da cultura e tradições indígenas. Palavras-chave: Educação Escolar Indígena. Interculturalidade. Prática Pedagógica.
Sexo e sexualidade: tabu, polêmica ou conceitos polissêmicos? Reflexões sobre/para a formação de educadores
Authors: Martines Elizabeth Antônia Leonel de Moraes , Rossarolla Juliana Negrello
Published: May 2018

Este trabalho tem como objetivo realizar uma “reflexão sobre a ação e sobre a reflexão-na-ação” a partir de dois encontros de uma pesquisa-ação colaborativa (IBIAPINA, 2008) sobre e para a formação de educadores sexuais para atuarem na Educação Básica, a qual aliou a formação-investigação de uma mestranda com o processo de formação inicial em uma Licenciatura em Ciências Biológicas de um Instituto Federal amazônico. Os encontros desta pesquisadora com os estudantes (colaboradores) consistiram em ações diagnósticas, estudos de textos e diálogos sobre a questão “O que é sexo e sexualidade? Você se sente preparado para atuar em educação sexual?”. O registro dos dados foi realizado em planejamentos dos encontros, videogravação da interação e registro ampliado realizado nas vinte e quatro horas subsequentes. Os vídeos foram analisados novamente alguns meses depois para reflexão mais aprofundada com a análise do discurso, de acordo com referencial de Schön (1992) e Foucault (1999). Constatou-se que a temática é complexa, não aparece no Projeto Pedagógico do Curso, mas os alunos vivenciaram várias atividades na prática formativa, especialmente no PIBID, por iniciativa de alguns professores-formadores, mas as mesmas foram consideradas insuficientes. Concluiu-se com a convicção de que os professores necessitam de uma formação permanente e de trabalho coletivo na escola (especialmente através da pesquisa-ação colaborativa) para exercerem com responsabilidade e compromisso social a tarefa de educadores sexuais. Palavras-chave: Educação Sexual. Formação de Professores. Pesquisa-ação Colaborativa.
E-mobility according to VDL Bus and Coach
Authors: Rusak Zbigniew
Published: May 2018

In the recent years electromobility is an important factor of achieving goals of European transport policy for the first half of the 21st century. Using electric buses in the public transport allows to reduce the use of petroleum-derived fuels and emission of exhaust and greenhouse gases. Bus manufacturers are introducing changes to products strategies by offering electric buses, adapted to local needs. This article presents technical and operating solutions used in VDL buses.
Labor law in transport services carried out in the European Union
Authors: Hartleb Agnieszka
Published: May 2018

Transport operations in various Member States conduct research on the posted worker, work with many burdens, and the practical difficulties involved in fulfilling the responsibilities in the duties law. A multitude of rules and regulations excluding struggling carriers with over-burdened costs, depending on competitiveness and departure to the European market.
Bi-Bazilevič functions of complex order involving Ruscheweyh type q-difference operator
Authors: Murugusundaramoorthy Gangadharan , Bulut Serap
Published: May 2018

In this paper, we define a new subclass of bi-univalent functions involving q-difference operator in the open unit disk. For functions belonging to this class, we obtain estimates on the first two Taylor-Maclaurin coefficients |a2| and |a3|.
Estimate for initial MacLaurin coefficients of certain subclasses of bi-univalent functions of complex order associated with the Hohlov operator
Authors: Murugusundaramoorthy Gangadharan , Bulboacă Teodor
Published: May 2018

In this paper, we define a new subclass of bi-univalent functions involving a Hohlov operator in the open unit disk. For functions belonging to this class, we obtain estimates on the first two Taylor-Maclaurin coefficients |a
2
| and |a
3
|.
Mutations in SURF1 are important genetic causes of Leigh syndrome in Slovak patients
Authors: Danis Daniel , Brennerova Katarina , Skopkova Martina , Kurdiova Timea , Ukropec Jozef , Stanik Juraj , Kolnikova Miriam , Gasperikova Daniela
Published: May 2018

Objectives. Leigh syndrome is a progressive early onset neurodegenerative disease typically presenting with psychomotor regression, signs of brainstem and/or basal ganglia disease, lactic acidosis, and characteristic magnetic resonance imaging findings. At molecular level, deficiency of respiratory complexes and/or pyruvate dehydrogenase complex is usually observed. Nuclear gene SURF1 encodes an assembly factor for cytochrome c-oxidase complex of the respiratory chain and autosomal recessive mutations in SURF1 are one of the most frequent causes of cytochrome c-oxidase-related Leigh syndrome cases. Here, we aimed to elucidate the genetic basis of Leigh syndrome in three Slovak families.

Methods and results. Three probands presenting with Leigh syndrome were selected for DNA analysis. The first proband, presenting with atypical LS onset without abnormal basal ganglia magnetic resonance imaging findings, was analyzed with whole exome sequencing. In the two remaining probands, SURF1 was screened by Sanger sequencing. Four different heterozygous mutations were identified in SURF1: c.312_321delinsAT:p.(Pro104Profs*1), c.588+1G>A, c.823_833+7del:p. (?) and c.845_846del:p.(Ser282Cysfs*9). All the mutations are predicted to have a loss-of-function effect.

Conclusions. We identified disease-causing mutations in all three probands, which points to the important role of SURF1 gene in etiology of Leigh syndrome in Slovakia. Our data showed that patients with atypical Leigh syndrome phenotype without lesions in basal ganglia may benefit from the whole exome sequencing method. In the case of probands presenting the typical phenotype, Sanger sequencing of the SURF1 gene seems to be an effective method of DNA analysis.
Training Tips for the Transformer Model
Authors: Popel Martin , Bojar Ondřej
Published: May 2018

This article describes our experiments in neural machine translation using the recent Tensor2Tensor framework and the Transformer sequence-to-sequence model (Vaswani et al., 2017). We examine some of the critical parameters that affect the final translation quality, memory usage, training stability and training time, concluding each experiment with a set of recommendations for fellow researchers. In addition to confirming the general mantra “more data and larger models”, we address scaling to multiple GPUs and provide practical tips for improved training regarding batch size, learning rate, warmup steps, maximum sentence length and checkpoint averaging. We hope that our observations will allow others to get better results given their particular hardware and data constraints.
Improving Topic Coherence Using Entity Extraction Denoising
Authors: Cardenas Ronald , Bello Kevin , Coronado Alberto , Villota Elizabeth
Published: May 2018

Managing large collections of documents is an important problem for many areas of science, industry, and culture. Probabilistic topic modeling offers a promising solution. Topic modeling is an unsupervised machine learning method and the evaluation of this model is an interesting problem on its own. Topic interpretability measures have been developed in recent years as a more natural option for topic quality evaluation, emulating human perception of coherence with word sets correlation scores. In this paper, we show experimental evidence of the improvement of topic coherence score by restricting the training corpus to that of relevant information in the document obtained by Entity Recognition. We experiment with job advertisement data and find that with this approach topic models improve interpretability in about 40 percentage points on average. Our analysis reveals as well that using the extracted text chunks, some redundant topics are joined while others are split into moreskill-specifictopics. Fine-grained topics observed in models using the whole text are preserved.
An evaluation of the ICON® mask fixation: curing characteristics of the thermoplastic fixation and implications for patient workflow
Authors: Prasad Samendra , Podgorsak Matthew , Plunkett Robert , Prasad Dheerendra
Published: May 2018

Background

Thermoplastic mask immobilization is used to perform hypo-fractionated treatments with the Gamma Knife ICON®.

Materials and methods

We evaluated the curing characteristics of the ICON® Nanor mask using force sensing resistors coupled with a data logging tool designed by us.

Results

For patients being treated with masks made the same day as the treatment, often in the same sitting with no removal and replacement of the patient from the treatment cradle, based on the curves 80% of the force of fixation is reached at 30 minutes.

Conclusions

Allowing for curing over 10-15 minutes and the subsequent localizing and delivery Cone beam CT (CBCT)s as well as the plan evaluation this is a reasonable time to start of therapy. For more exacting targets that are still requiring hypo-fractionation a cure period of 15 hours or greater will ensure that maximum rigidity of fixation is achieved.
Shakespearean Drama in Miloš Pietor›S Work: Between Prologue and Epilogue
Authors: Sládeček Ján
Published: May 2018

William Shakespeare’s work has a very specific place in Miloš Pietor’s professional biography: it starts at the beginning of the artist’s creative period and then again at the end of his professional life. The study is devoted to this part of the director’s work. It analyzes the plays Merry Wives of Windsor (P. Jilemnický Theatre, 1963), Hamlet (Nová scéna Theatre 1974), comedy Love’s Labour’s Lost) (Nová scéna Theatre 1976) and presents the directorial and dramaturgical concept of Pietor’s first production after November 1989, The Merchant of Venice (1991). His planned premiere at the Slovak National Theatre (Slovenské národné divadlo) did not take place; the work was cancelled due to the director’s tragic death.
Three Slovak Art Films and Their Attempt to Reach Cinematic Audiences
Authors: Križková Eva
Published: May 2018

The text analyzes the distribution of three Slovak films created in 2017 (Piata loď (Little Harbour), Špina (Filthy), Nina to Slovak cinemas. This year new Slovak films reached 1,414,132 cinemagoers, which is a 21.13% share of total cinema admissions. This is the highest annual number recorded since the establishment of the Slovak Republic (1993). The study looks for an answer to the question, Why do some Slovak films achieve higher admissions then others? It also seeks to point out the variability of the criteria to measure the success of a film with the audience.
Astonishing XVI. Annual Europe Theatre Prize Set in Ancient But Modern Rome
Authors: Knopová Elena
Published: May 2018

The text briefly illustrates the history of the Europe Theatre Prize (ETP) and its current form. The author offers insights into the work of theatrical performers who received prizes in the categories of Special Prize and Europe Prize Theatrical Realities. While also briefly apprises the productions seen during the 16th ETP. In 2017, the Special Prize category was won by: Wole Soyinka, Fadhel Jaïbi, Dimitris Papaioannou, the Europe Prize Theatrical Realities was won by: Susanne Kennedy, Yael Ronen, Theatre NO99, Alessandro Sciarroni, Jernej Lorenci. The main prizes were won by actors Jeremy Irons and Isabelle Huppert. Productions also presented in this week included the works of directors Petr Stein, Robert Wilson and Giorgio Barberio Corsetti former recipients of the Europe Theatre Prize.
Simulation of Congestion Phenomena and Strategic Passenger Behaviour on Transit Networks
Authors: Bresciani Miristice Lory Michelle , Menichetti Dario , Gentile Guido
Published: May 2018

This article focuses on the simulation of transit networks, including passengers’ congestion phenomena and strategic behaviour, as a tool for planning and operation. Specifically, it describes a model of user equilibrium on large-scale transit networks considering on-board overcrowding, queuing at stops and dwelling delay, and representing in addition the effects of random events, such as the availability of seats and the waiting of vehicles, through hyperarcs. The assignment algorithm computes a strategy-based user equilibrium with implicit hyperpath enumeration by solving a fixed-point formulation, through a gradient projection method, which highly improves convergence performance. The model was implemented in .net as a dll that uses the software PTV Visum as I/O source. This article will focus on the model formulation and its capability of reproducing the target phenomena, while the results of model validation and testing will be described in a following paper.
Redescription and New Host Record of Diplostamenides Sciaenae (Monogenea, Microcotylidae) and Its Phylogenetic Status Using Molecular Markers
Authors: Verma A. K. , Verma J. , Agrawal N.
Published: May 2018

A new host and new locality is recorded for Diplostamenides sciaenae (Goto, 1894) Lebedev, Parukhin et Roitman, 1970 from Johnius belangerii at Versova dock landing centre, Mumbai, India. The morphometric comparison of D. sciaenae with previously published data, provided redescription complements results of molecular analysis. The partial 28S and 18S rRNA gene sequences of D. sciaenae were amplified, sequenced through PCR and deposited to GenBank database. The BLASTn searches revealed the significant closeness of D. sciaenae to other microcotylid parasites in large and small ribosomal subunits. Th e phylogenetic tree analyses with neighbor joining and minimum evolution methods also expressed belonging of D. sciaenae to Microcotylidae.
Finding of Pseudobacciger Harengulae (Digenea, Faustulidae) in the Mediterranean Horse Mackerel, Trachurus Mediterraneus (Actinopterygii, Carangidae), from The Gulf of Odessa, Black Sea, Ukraine
Authors: Hulak Bohdan , Kvach Yuriy
Published: May 2018

Pseudobacciger harengulae (Yamaguti, 1938) is a parasite of herrings (Actinopterygii, Clupeidae) in both Atlantic and Pacific oceans. We record this parasite from the gut of Trachurus mediterraneus (Steindachner, 1868) (Actinopterygii, Carangidae) from the Gulf of Odessa, Black Sea, Ukraine. A description and images of the specimens are provided. This is the first record of P. harengulae in a carangid fish, and the second record of accidental infestation of T. mediterraneus with faustulid flukes in the Black Sea.
Age and Growth Comparison of Diploid and Triploid Species of Crucian Carps (Cypriniformes, Cyprinidae) in the Water Bodies of the DNIPRO Basin
Authors: Kokodiy S. V.
Published: May 2018

The genetic structure of crucian carps colonies in Ukrainian water bodies was defined by gene marking. The sexual structure and ploidy were investigated, the duration of spawners maturation, life-span, rate of growth and the linear growth of independent species and biotypes were defined. The comparative biological analysis showed that virtually all the researched crucian carps had low linear growth index and early maturation terms. Th e hybrid individuals of C. auratus-C. carassius during the first years of life were characterized by the high rate of growth which was most likely determined by the “hybrid power” which is kept by this biotype only within the starting phase of existence, after which the active growth is significantly reduced. Th e individual biological peculiarities of peculiar species and biotypes of crucian carps do not depend on their genetic nature but in most cases are defined by the external living conditions.
New Records of Hoverflies (Diptera, Syrphidae) from Ukraine. II. Brachyopini and Merodontini
Authors: Prokhorov A. V. , Popov G. V. , Zaika M. I.
Published: May 2018

Seven hoverfly species of the tribes Brachyopini and Merodontini (subfamily Eristalinae): Brachyopa maculipennis Thompson, 1980, B. plena Collin, 1939, B. vittata (Zetterstedt, 1843), Myolepta obscura Becher, 1882, Orthonevra geniculata (Meigen, 1830), Merodon moenium (Wiedemann in Meigen, 1822) and Psilota atra (Fallén, 1817) are recorded from Ukraine for the first time. Distributions of these species are summarized and diagnoses of the species are provided.
SELF REGULATED LEARNING SEBAGAI UPAYA MENINGKATKAN HASIL BELAJAR KOSAKATA BAHASA ARAB BAGI MAHASISWA
Authors: Rusuly Usfiyatur
Published: May 2018

This research is designed as a research action performed to improve students' understanding of Arabic vocabularies by taking several actions aimed at improving (1) Students’ motivation in practicing self regulated learning, (2) Students’ readiness before entering class, and (3) Students’ involvement in teaching and  learning process. The subject of the research was the first semester female students of C-26 mubtadi' class in the Special Program of Arabic Language Learning. This research is conducted in a dynamic and complementary process consisting of four important cycles, for example: planning, action, observation, and reflection. From the analysis, it is revealed that there were some actions that positively affected the students' understanding of Arabic vocabularies.
Aplikasi Data Mining untuk Mencari Pola Asosiasi Tracer Study Menggunakan Algoritma FOLDARM
Authors: Zahrotun Lisna , Setiadi Tedy , Haryadi Taufik Mufti
Published: May 2018

A tracer study is an approach that allows higher education institutions to obtain information about possible deficiencies during educational process and learning process and activity planning for improvement. Institute of Student Affairs never do a tracer study data analysis, although tracking of graduate student has been periodically using web-based application but the previous data is still in old format. Tracer study process is only once time in order to completed   accreditation requirement for department. In this research we will focus in developing the application using FOLDARM method for student tracer study. Application is created using the CI Framework programming language with   Mysql as backend database. The test is done using lift ratio method. The result show, association of the patterns are counted by 3, 24% support and confident 45% and it that meet the criteria. By using lift ratio test, the pattern that has the strongest relationship is if the waiting period in finding a job is 3- 5,9 month and first salary is below Rp. 1,572,200,-  and IPK is between 2.75 - 3.50 and graduation age is between 15-24 years old.