bluuebunny/crossref_metadata_2025 huggingface dataset:
Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies
Authors: Gandhi Gopalsamy Rajiv , Vasconcelos Alan Bruno Silva , Wu Ding-Tao , Li Hua-Bin , Antony Poovathumkal James , Li Hang , Geng Fang , Gurgel Ricardo Queiroz , Narain Narendra , Gan Ren-You
Published: September 2020

The consumption of plant-based food is important for health promotion, especially concerning the prevention and management of chronic diseases. Flavonoids are the main bioactive compounds in citrus fruits, with multiple beneficial effects, especially antidiabetic effects. We systematically review the potential antidiabetic action and molecular mechanisms of citrus flavonoids based on in vitro and in vivo studies. A search of the PubMed, EMBASE, Scopus, and Web of Science Core Collection databases for articles published since 2010 was carried out using the keywords citrus, flavonoid, and diabetes. All articles identified were analyzed, and data were extracted using a standardized form. The search identified 38 articles, which reported that 19 citrus flavonoids, including 8-prenylnaringenin, cosmosiin, didymin, diosmin, hesperetin, hesperidin, isosiennsetin, naringenin, naringin, neohesperidin, nobiletin, poncirin, quercetin, rhoifolin, rutin, sineesytin, sudachitin, tangeretin, and xanthohumol, have antidiabetic potential. These flavonoids regulated biomarkers of glycemic control, lipid profiles, renal function, hepatic enzymes, and antioxidant enzymes, and modulated signaling pathways related to glucose uptake and insulin sensitivity that are involved in the pathogenesis of diabetes and its related complications. Citrus flavonoids, therefore, are promising antidiabetic candidates, while their antidiabetic effects remain to be verified in forthcoming human studies.
Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials
Authors: Vlasschaert Caitlyn , Goss Chloe J. , Pilkey Nathan G. , McKeown Sandra , Holden Rachel M.
Published: September 2020

Matrix gla protein (MGP) is an important vitamin K-dependent inhibitor of vascular calcification. High levels of uncarboxylated, dephosphorylated MGP have been associated with vascular calcification and are responsive to vitamin K treatment. In this systematic review, we summarize the available evidence examining whether vitamin K supplementation improves surrogate measures of cardiovascular disease including artery and valve calcification, atherosclerosis and artery stiffening. Data from controlled trials of adults were obtained by searching Ovid MEDLINE, Embase, the Cochrane Central Register of Controlled Trials and the Web of Science Core Collection. We identified nine randomized controlled trials for review, including trials of vitamin K1 or vitamin K2 supplementation, that assessed a surrogate measure of cardiovascular disease including arterial calcification, atherosclerosis or arterial stiffening. For each trial, the risk of bias was assessed applying Cochrane Collaboration methodology. The findings indicate that vitamin K does not consistently prevent progression of calcification, atherosclerosis or arterial stiffness. There may be some benefit in people with calcification at study entry. Studies were heterogenous, with relatively short follow-up and outcome measures were varied. While vitamin K supplementation clearly improves the carboxylation of dephosphoylated MGP, its role in mitigating vascular calcification is uncertain, based on current evidence.
Effect of a Nutrient-Rich, Food-Based Supplement Given to Rural Vietnamese Mothers Prior to or during Pregnancy on the Trajectories of Nutrient Biomarkers
Authors: Goletzke Janina , Nga Hoang T. , Quyen Phi N. , Ngu Tu , King Janet C.
Published: September 2020

Nutrient interventions initiated after conception tend to have modest effects on maternal nutritional status and pregnancy outcomes. Thus, we compared the association between micronutrient intakes and the trajectories of their biomarkers before and during pregnancy. Data from a randomized trial of the effect of a nutrient-rich, food-based supplement given to 317 Vietnamese women prior to or during pregnancy on birth outcomes were used to assess nutrient intakes with biomarker trajectories of zinc, iron, folate, cobalamin, and vitamin A using linear mixed regression models. The circulating plasma or serum trajectories of all five micronutrients were associated to their baseline levels (p < 0.0001). Plasma zinc trajectories were also related to farm work (p = 0.024). Cobalamin and vitamin A trajectories were associated with gestational weight gain (p = 0.003 and p = −0.037, respectively). In this population of rural Vietnamese women, nutrient intakes during pregnancy did not affect biomarker trajectories. The primary determinant of each nutrient biomarker trajectory was its respective baseline level prior to conception.
Screening of Bacterial Quorum Sensing Inhibitors in a Vibrio fischeri LuxR-Based Synthetic Fluorescent E. coli Biosensor
Authors: Qin Xiaofei , Vila-Sanjurjo Celina , Singh Ratna , Philipp Bodo , Goycoolea Francisco M.
Published: September 2020

A library of 23 pure compounds of varying structural and chemical characteristics was screened for their quorum sensing (QS) inhibition activity using a synthetic fluorescent Escherichia coli biosensor that incorporates a modified version of lux regulon of Vibrio fischeri. Four such compounds exhibited QS inhibition activity without compromising bacterial growth, namely, phenazine carboxylic acid (PCA), 2-heptyl-3-hydroxy-4-quinolone (PQS), 1H-2-methyl-4-quinolone (MOQ) and genipin. When applied at 50 µM, these compounds reduced the QS response of the biosensor to 33.7% ± 2.6%, 43.1% ± 2.7%, 62.2% ± 6.3% and 43.3% ± 1.2%, respectively. A series of compounds only showed activity when tested at higher concentrations. This was the case of caffeine, which, when applied at 1 mM, reduced the QS to 47% ± 4.2%. In turn, capsaicin, caffeic acid phenethyl ester (CAPE), furanone and polygodial exhibited antibacterial activity when applied at 1mM, and reduced the bacterial growth by 12.8% ± 10.1%, 24.4% ± 7.0%, 91.4% ± 7.4% and 97.5% ± 3.8%, respectively. Similarly, we confirmed that trans-cinnamaldehyde and vanillin, when tested at 1 mM, reduced the QS response to 68.3% ± 4.9% and 27.1% ± 7.4%, respectively, though at the expense of concomitantly reducing cell growth by 18.6% ± 2.5% and 16% ± 2.2%, respectively. Two QS natural compounds of Pseudomonas aeruginosa, namely PQS and PCA, and the related, synthetic compounds MOQ, 1H-3-hydroxyl-4-quinolone (HOQ) and 1H-2-methyl-3-hydroxyl-4-quinolone (MHOQ) were used in molecular docking studies with the binding domain of the QS receptor TraR as a target. We offer here a general interpretation of structure-function relationships in this class of compounds that underpins their potential application as alternatives to antibiotics in controlling bacterial virulence.
The Mediatization of Camino De Santiago: Between the Pilgrimage Narrative and Media Circulation of the Narrative
Authors: de Sousa Marco Túlio , da Rosa Ana Paula
Published: September 2020

In this article, we seek to analyze the mediatization of pilgrims’ narratives on Camino de Santiago. Centuries ago, pilgrims were deprived of contact with their homes for extended periods. The narrative of the experience was only shared with their loved ones once they had arrived home. In the 20th century, landline telephones, computers connected to the Internet, and smartphones gradually reduced the time necessary to share these stories with the outside world. Upon analyzing pilgrimage narratives published on the Internet (Facebook, blogs), we observe that the intimate experience of pilgrims has become a media product that, when circulated, interferes in both the storytelling and the actual pilgrimage experience.
Ecological Risk Assessment Based on Land Cover Changes: A Case of Zanzibar (Tanzania)
Authors: Omar Hassan , Cabral Pedro
Published: September 2020

Land use and land cover (LULC) under improper land management is a major challenge in sub-Saharan Africa and has drastically affected ecological security. Addressing environmental impacts related to this challenge requires efficient planning strategies based on the measured information of land use patterns. This study assessed the ecological risk index (ERI) of Zanzibar based on LULC. A random forest classifier was used to classify three Landsat images of Zanzibar for the years 2003, 2009, and 2018. Then, a land change model was employed to simulate the LULC changes for 2027 under a business-as-usual (BAU), conservation, and extreme scenarios. Results showed that the built-up areas and farmland of Zanzibar Island have increased constantly, while the natural grassland and forest cover have decreased. The forest, agricultural, and grassland were highly fragmented into several small patches. The ERI of Zanzibar Island increased at a constant rate and, if the current trend continues, this index will increase by up to 8.9% in 2027 under an extreme scenario. If a conservation scenario is adopted, the ERI will increase by 4.6% whereas if a BAU policy is followed, this value will increase by 6.2%. This study provides authorities with useful information to understand better the ecological processes and LULC dynamics and prevent unmanaged growth and haphazard development of informal housing and infrastructure.
A Novel Coarse-to-Fine Method of Ship Detection in Optical Remote Sensing Images Based on a Deep Residual Dense Network
Authors: Chen Liqiong , Shi Wenxuan , Fan Cien , Zou Lian , Deng Dexiang
Published: September 2020

Automatic ship detection in optical remote sensing images is of great significance due to its broad applications in maritime security and fishery control. Most ship detection algorithms utilize a single-band image to design low-level and hand-crafted features, which are easily influenced by interference like clouds and strong waves and not robust for large-scale variation of ships. In this paper, we propose a novel coarse-to-fine ship detection method based on discrete wavelet transform (DWT) and a deep residual dense network (DRDN) to address these problems. First, multi-spectral images are adopted for sea-land segmentation, and an enhanced DWT is employed to quickly extract ship candidate regions with missing alarms as low as possible. Second, panchromatic images with clear spatial details are used for ship classification. Specifically, we propose the local residual dense block (LRDB) to fully extract semantic feature via local residual connection and densely connected convolutional layers. DRDN mainly consists of four LRDBs and is designed to further remove false alarms. Furthermore, we exploit the multiclass classification strategy, which can overcome the large intra-class difference of targets and identify ships of different sizes. Extensive experiments demonstrate that the proposed method has high robustness in complex image backgrounds and achieves higher detection accuracy than other state-of-the-art methods.
MRFF-YOLO: A Multi-Receptive Fields Fusion Network for Remote Sensing Target Detection
Authors: Xu Danqing , Wu Yiquan
Published: September 2020

High-altitude remote sensing target detection has problems related to its low precision and low detection rate. In order to enhance the performance of detecting remote sensing targets, a new YOLO (You Only Look Once)-V3-based algorithm was proposed. In our improved YOLO-V3, we introduced the concept of multi-receptive fields to enhance the performance of feature extraction. Therefore, the proposed model was termed Multi-Receptive Fields Fusion YOLO (MRFF-YOLO). In addition, to address the flaws of YOLO-V3 in detecting small targets, we increased the detection layers from three to four. Moreover, in order to avoid gradient fading, the structure of improved DenseNet was chosen in the detection layers. We compared our approach (MRFF-YOLO) with YOLO-V3 and other state-of-the-art target detection algorithms on an Remote Sensing Object Detection (RSOD) dataset and a dataset of Object Detection in Aerial Images (UCS-AOD). With a series of improvements, the mAP (mean average precision) of MRFF-YOLO increased from 77.10% to 88.33% in the RSOD dataset and increased from 75.67% to 90.76% in the UCS-AOD dataset. The leaking detection rates are also greatly reduced, especially for small targets. The experimental results showed that our approach achieved better performance than traditional YOLO-V3 and other state-of-the-art models for remote sensing target detection.
Overt Infection with Chronic Bee Paralysis Virus (CBPV) in Two Honey Bee Colonies
Authors: Dittes Julia , Schäfer Marc O. , Aupperle-Lellbach Heike , Mülling Christoph K. W. , Emmerich Ilka U.
Published: September 2020

Chronic Bee Paralysis Virus (CBPV), a widespread honey bee RNA virus, causes massive worker bee losses, mostly in strong colonies. Two different syndromes, with paralysis, ataxia and flight incapacity on one hand and black hairless individuals with shortened abdomens on the other, can affect a colony simultaneously. This case report presents two Apis mellifera carnica colonies with symptoms of paralysis and hairless black syndrome in 2019. Via RT-PCR, a highly positive result for CBPV was detected in both samples. Further problems, such as a Nosema infection and Varroa infestation, were present in these colonies. Therapy methods were applied to colony 1 comprising queen replacement, shook swarm method and Varroa control, whereas colony 2 was asphyxiated after queen loss and colony weakening. After therapy, colony 1 was wintered without symptoms. Beekeeping and sanitary measures can save a CBPV-infected colony, while further complications result in total colony loss.
The Curse of Ham: Biblical Justification for Racial Inequality?
Authors: Isbell Charles David
Published: September 2020

The story of the drunkenness of Noah that caused him to remove his clothing and thus provided the opportunity for his son, Ham, to “see” him (Genesis 9:20‒27), has never received an interpretation that has been unanimously adopted by interpreters over the centuries. By examining the concept of “nakedness” as it functions in biblical legislation, this article argues that the most plausible understanding of the passage is that Ham committed incest with the wife of his father, Noah. Concomitantly, it becomes clear that the literalist idea of “race” used to undergird either slavery or any comparable form of white supremacy cannot be derived exegetically from the passage.
Fidelity of the delivery of NHS Health Checks in general practice: an observational study
Authors: Paxton Ben , Mills Katie , Usher-Smith Juliet A
Published: September 2020

Background

The NHS Health Check programme aims to reduce the risk of common preventable diseases by providing risk information and behaviour change advice. Failure to deliver the consultation appropriately could undermine its efficacy. To date, to the authors’ knowledge, there are no published data on the fidelity of delivery of NHS Health Checks.

Aim

To assess the fidelity of delivery of NHS Health Checks in general practice.

Design & setting

Fidelity assessment of video and audio recordings of NHS Health Check consultations conducted in four GP practices across the East of England.

Method

A secondary analysis of 38 NHS Health Check consultations, which were video or audio recorded as part of a pilot study of introducing discussions of cancer risk into NHS Health Checks. Using a checklist based on the NHS Health Check Best Practice Guidance, fidelity of delivery was assessed as the proportion of key elements completed during the consultations.

Results

The mean number of elements of the NHS Health Check completed across all consultations was 14.5/18 (80.6%), with a range of 10 to 17 (55.6% to 94.4%). The mean fidelity for risk assessment, risk communication, and risk management sections was 8.7/10 (87.0%), 4.1/5 (82.0%), and 1.7/3 (56.7%), respectively. Clinically appropriate lifestyle advice was given in 34/38 consultations. Elements with the lowest fidelity were ethnicity assessment (n = 12/38; 31.6%), family history of cardiovascular disease (CVD) assessment (n = 25/38; 65.8%), AUDIT-C communication (n = 13/38; 34.2%), and dementia risk management (n = 6/38; 15.8%).

Conclusion

Although fidelity of delivery was high overall, important elements of the NHS Health Check were being regularly omitted. Opportunities for behaviour change, particularly relating to alcohol consumption and dementia risk management, may be being missed.
Emblematic Literature as a Form of Biblical Hermeneutics
Authors: Levchenko Nataliia , Liamprekht Olena , Zosimova Oksana , Varenikoba Olena , Boiko Svitlana
Published: September 2020

The article defines the basic principles of the influence of biblical hermeneutics on the poetics of Ukrainian Baroque emblematic literature, which were determined by its general development trends. The four-sense biblical hermeneutics, founded by the Greek and Roman Church Fathers, played an important role in the formation of Ukrainian Baroque literature that mainly developed within the theological framework. The principles of biblical hermeneutics eventually began to go beyond the theological literature. Thus, the medieval interest in symbol and allegory led to the appearance of “empresas” – symbolic drawings that became fashionable at the royal courts of Europe in the 15th century. The Renaissance misunderstanding about the nature of Egyptian hieroglyphs, their perception as ideographic writing through which Egyptian priests expressed their wisdom, led to the appearance of emblems, allegorical prints with long explanatory verses, aimed at giving some moral lessons. It was believed that the emblem could communicate truth to the mind more directly than with the help of words. It was reflected in the mind, while the person’s gaze wandered through the symbolic details of the emblem. The research provides evidence that a large number of literary works of the 17th century showed the influence of the emblem on the formation of symbolic representation, arranged to reveal the truth implicitly or explicitly through the sequential placement of the elements. Many poetic images of the 17th century come from well-known emblems, which were means of perceiving, interpreting, and opening the world of the Bible to the Baroque reader.
Atomistic Surface Passivation of CH
3
NH
3
PbI
3
Perovskite Single Crystals for Highly Sensitive Coplanar-Structure X-Ray Detectors
Authors: Song Yilong , Li Liqi , Bi Weihui , Hao Mingwei , Kang Yifei , Wang Anran , Wang Zisheng , Li Hanming , Li Xiaohui , Fang Yanjun , Yang Deren , Dong Qingfeng
Published: September 2020

Organic-inorganic halide perovskites (OIHPs) are recognized as the promising next-generation X-ray detection materials. However, the device performance is largely limited by the ion migration issue of OIHPs. Here, we reported a simple atomistic surface passivation strategy with methylammonium iodide (MAI) to remarkably increase the ion migration activation energy of CH
3
NH
3
PbI
3
single crystals. The amount of MAI deposited on the crystal surface is finely regulated by a self-assemble process to effectively suppress the metallic lead defects, while not introducing extra mobile ions, which results in significantly improved dark current stability of the coplanar-structure devices under a large electric field of 100 V mm
-1
. The X-ray detectors hence exhibit a record-high sensitivity above 700,000 
μ
C 

Gy

air

‐
1

 cm
‐2
under continuum X-ray irradiation with energy up to 50 keV, which enables an ultralow X-ray detection limit down to 1.5 nGy
air
 s
-1
. Our findings will allow for the dramatically reduced X-ray exposure of human bodies in medical imaging applications.
Peri-Infusional Adverse Reactions to Rituximab in Mexican Patients with Rheumatoid Arthritis
Authors: Arredondo-Garza Teresa , Majluf-Cruz Abraham , Irazoque-Palazuelos Fedra , Rivas-Jiménez María de la Luz , Martínez Alejandro , Reyes-Patatuchi Roberto , Mariscal-Ramírez Ignacio , López-Villanueva Ricardo Francisco , Gordillo-Huerta Vanesa , Loaiza-Cárdenas Carlos , Terán-Estrada Leobardo
Published: September 2020

Background. The treatment of rheumatoid arthritis (RA) has significantly improved since the introduction of biologics like rituximab. Rituximab achieves selective B lymphocyte depletion and, thereby, reduce inflammation. It has adverse reactions related to the immunogenic response. Objective. The aim of this study was to evaluate the frequency and severity of rituximab adverse reactions in Mexican patients with RA. Methods. A prospective, observational, descriptive, open-labeled, multicenter cohort study of intensive pharmacovigilance was conducted during 17 months in 10 hospitals. We included 335 adult patients with RA, 26 male an 309 female. They received two doses of rituximab (1000 mg) on days 1 and 15 in combination with methotrexate. Adverse reactions were graded according to the National Cancer Institute (NCI) scale and causality was established with the Naranjo algorithm. Infusions were classified as fast (0 to 180 minutes) and slow (> 181 minutes). The first and second infusions were compared. Results. The total number of infusion episodes recorded was 631 and 36 adverse reactions were informed in 24 patients (7.1 %). There were no differences between the variances of the first and second infusions. All the adverse reactions were considered mild to moderate (NCI Scale). According to Naranjo algorithm, the adverse reactions to rituximab were possible or probable. The infusion speed did not have an influence on the adverse reactions; whereas the incident rate was lower than that reported by other authors. Conclusions. Rituximab has a favorable safety profile in Mexican patients.
Current Pharmacological Therapy against COVID-19: A Latin American Perspective
Authors: Nicolalde Bryan , Añazco Diego , Mushtaq Mariam , Aguilar Ana , Terán Enrique
Published: September 2020

Introduction. SARS-CoV-2 infection is a public health emergency and several treatments against COVID-19 are in place while investigated simultaneously. Objective. To update on current pharmacological therapies against COVID-19, and its implications in Latin American countries. Material and Methods. Publications on PubMed and in open access journals regarding pharmacological interventions against SARS-CoV-2 infection were reviewed, followed by analysis of the protocols already in place in Latin American countries. Results. Recent clinical data showed that lopinavir/ritonavir therapy was not effective against severe SARS-CoV-2 infection; however, further trials are underway and will help define the role of this therapy. Remdesivir showed significant efficacy in vitro, and clinical improvement in a report of compassionate-use, but data from controlled trials is not available currently. Tocilizumab plays an important role during cytokine storm, and studies revealed promising results. Chloroquine and hydroxychloroquine showed efficacy in vitro but clinical data are controversial, then further trials are needed to assess their role. Convalescent plasma, tocilizumab, lopinavir/ritonavir, chloroquine, and hydroxychloroquine have been approved by the Infectious Diseases Society of America (IDSA) and the Food and Drug Administration (FDA) in the context of clinical research. Various Latin American countries have already implemented antimicrobial therapy within their local protocols. Conclusions. Promising agents, due to the emergency, are currently in some of the Latin American treatment protocols, although restricted to patients with non-favourable clinical course. Results from controlled clinical trials will be required to define the role of these drugs. Misuse and abuse of drugs can cause drug shortages if supply is not secured, and serious adverse effects might occur.
Investigation into the Protective Effects of Escin on Blood Cells and Cyclophosphamide-Induced Bone Marrow Toxicity in Rats
Authors: CENGİZ Mustafa , AYHANCI Adnan , KUTLU Hatice Mehtap
Published: September 2020

Cyclophosphamide (CPM) is an extensively used antineoplastic drug that induces toxicity in the health cell because of its metabolites. The main disadvantage of this drug is myelosuppression. Escin (ES) is a natural mixture of triterpenoid saponins that has biological properties such as antioxidant, anti-inflammation, and anti-edematous. The present study aims to investigate the possible effects of ES upon the toxic effects of CPM on blood cells and bone marrow. Spraque Dawley male rats were chosen and categorized into 4 different groups, including the control group, 200 mg/kg CPM, 10 mg/kg ES and ES+CPM. Rats in all groups were discontinued 1 day after injections. After the animals were cut under anesthesia, bone marrow and blood samples were collected. A fall in the number of erythrocyte, hemoglobin, hematocrit, leukocyte (97%), platelets (45%), and bone marrow cells (93.6%) was seen in the CPM group. Conversely, blood cells (erythrocyte, hemoglobin, hematocrit, leukocyte, and platelets), as well as bone marrow cells in ES + CPM had increased by comparison with CPM. Our results show that treating rats with a selected dose range of ES may help decrease the toxic effects of CPM upon blood cells and bone marrow.
COVID-19 PANDEMİSİ VE İNTİHAR
Authors: Emiral Emrah , Arslan Zehra , Gülümser Şuayip
Published: September 2020

COVID-19 enfeksiyonu bireyleri ve toplumları yalnızca fiziksel olarak etkilemekle kalmamış, tarihte yaşanan diğer viral enfeksiyonlar gibi ruhsal olarak da etkilemiştir. Ruhsal etkilenmenin kötü sonuçlarından biri olan, nedenleri ve sonuçları itibariyle bir halk sağlığı problemi olarak ele alınması gereken intihar vakaları bu gibi dönemlerde artmaktadır. Birçok çalışma ile pandemi sürecinde intihar düşünce ve davranışına zemin oluşturan faktörler tespit edilmeye çalışılmıştır. Bu çalışmamızda intihar düşünce ve davranışlarının pandemi sürecinde hangi faktörlerden ne şekilde etkilendiğini, hangi yöntemlerin bu dönemde arttığını ve engellenmesi için alınabilecek önlemlerin neler olduğunun incelenmesi amaçlanmıştır.
COVID-19’UN TOPLUMDA YAYILIMINI ÖNLEMEYE YÖNELİK İLAÇ DIŞI HALK SAĞLIĞI ÖNLEMLERİ
Authors: Erkal Emin , Ses Ayşe , Aydın Saliha , Çalışkan Deniz
Published: September 2020

COVID-19'u tedavi etmek veya önlemek için etkili spesifik ilaç veya aşı olmadığı için halk sağlığı önlemleri salgına yanıt vermenin tek yoludur. Hastalığın yayılmasını kontrol etmek ve kontrol önlemlerinin sürekli uygulanmasını sağlamak için etkili şekilde sürveyansın yapılması kritik önem taşımaktadır. Halk sağlığı önlemlerinden özellikle el ve solunum hijyeni, sosyal mesafenin uygulanması, izolasyon, karantina; solunum hastalıklarının yavaş bulaşması ve sağlık kuruluşlarının bu hastalıklarla daha iyi başa çıkabilmesi için önemlidir. Sosyal mesafe, özellikle toplum yayılımının gerçekleştiği, ancak vakalar arasındaki bağlantıların belirsiz olduğu durumlarda yararlıdır. Mesafe uzadıkça bulaşın azaldığı, maske kullanımının hem sağlık çalışanları için hem de toplumda etkene maruz kalan insanlar için koruyucu olduğu gösterilmiştir. Yapılan çalışmalarda ikinci bir dalgadan korunmak için toplum bağışıklığının henüz yetersiz olması nedeniyle alınan halk sağlığı önlemlerinin devam etmesi gerektiğinin göstergesidir. Sürecin uzaması bireylerde önlemlere uyumda azalmaya ve uyum yorgunluğuna da neden olabilir. Salgının kontrol alınmasıyla politika yapıcılar sağlık sistemi kapasitesinin aşılmadan, halk sağlığı önlemleri ile kontrollü sosyal yaşamı benimsemektedir.
Sonuç olarak; COVID-19 salgını kontrolü için en önemli basamak olan halk sağlığı önlemlerin sürekliliği toplumun sosyokültürel yapısı göz önüne alınarak sağlanmalıdır. Önlemlerin uygulanabilir olması, bireysel uyum için ekonomik altyapının sağlanması, salgın başından itibaren her ülkenin sürveyans kapasitesini önemli düzeyde artırması gereklidir.
YÜKSEK TİRAJ YAPAN YERLİ VE YABANCI İNTERNET GAZETELERİNİN KORONAVİRÜS HASTALIĞI İLE İLGİLİ HABER İÇERİKLERİNİN İNCELENMESİ
Authors: Sungur Sevda , Yücel Ezgi , Metintas Selma , Önsüz Muhammed Fatih
Published: September 2020

Günümüzde çok önemli bilgi platformu haline gelen internetin, COVID-19 pandemisinde kitlelerin bilgilendirilmesinde kullanılması hedeflenmektedir. Çalışmada, yerli ve yabancı internet gazetelerinde COVID-19 ile ilgili yer alan haberlerin kategorileri ve sağlık haberlerinin konularına göre dağılımlarının nicelik ve nitelik yönünden incelenmesi amaçlandı. Çalışmada 17.01.2020 ile 10.03.2020 tarihleri arasında en çok tıklanan üç yerli ve üç yabancı internet gazetesinde yer alan 12.829 haber içerik analizi yöntemi ile incelendi. Tüm haberler içerisinde dördüncü sırada olan sağlık kategorisinde yer alan haberler (n=768; %5,50) içerik açısından analiz edilip, ele aldığı konulara göre kategorilendirildi. Günlük ortalama haber sayısının yerli gazetelerde 6’ncı haftada, yabancı gazetelerde 6 ve 7’nci haftalarda istatiksel olarak anlamlı artış gösterdiği saptandı. Sağlık kategorisindeki haberlerde ise yerli gazetelerde 7’nci ve yabancı gazetelerde 6’ncı haftada anlamlı artış görüldü. Tüm haberlerin dağılımı incelendiğinde ilk sırada ‘’dünya’’ (n=5628; %43,9) ve 4. sırada ise ‘’sağlık‘’ (n=818; %6,40) kategorisindeki haberler yer almaktaydı. Sağlık haberlerinin konusuna göre dağılımında ise en çok sayıda haberin ‘’koruyucu önlem’’ (n=115; %59), en az sayıda haberin ‘’tedavi’’ kategorisinde (n=152; %19,8) olduğu tespit edildi. Sonuç olarak internet gazeteleri sağlık otoriteleri ile eşgüdümle çalıştıklarında pandemi kontrolünde önemli görevler üstlenebilirler.
Cubo Didáctico como complemento a terapias de desconcentración intelectual
Authors: Del Angel-López Hulda Zulema , Oros-Mendez Lya Adlih
Published: September 2020

Didactic Cube as a complement to intellectual deconcentration therapies. Children's therapies to increase concentration are methods that help to improve the performance of patients suffering from ADHD (Attention Deficit Hyperactivity Disorder), where different teaching tools can be used to support family members and therapists to carry out activities recommended to improve attention in children mainly. There are several materials that therapists can support to focus on the realization of a program that develops the ability to concentrate in preschool children. Objectives, Methodology. Contribute to the equipment of the Center for Rehabilitation and Special Education of San Luis Potosí (CREE), supporting therapies for children mainly with problems of attention deficit and slow learning, through didactic means that stimulate their training and intellectual development. Firstly, the needs of patients with attention deficit diagnosed for rehabilitation are identified, then the needs of the CREE are identified with respect to a didactic toy that subserve and complements the rehabilitation and stimulation in therapies focused on attention deficit and finally a cube is made, with the purpose that it is a didactic toy, which can support people with some intellectual disability in therapies. Contribution. The results focus on the consecutive use of a didactic cube to be able to perform the corresponding measurements in order to evaluate the effectiveness of its use in therapies with children who are deficient in the level of care and / or concentration.
Educación a distancia y aprendizaje personalizado adaptativo
Authors: Gutiérrez-Tornés Agustín Francisco , Canales-Cruz Alejandro , Zambrano-Dávila Juana Inés
Published: September 2020

The present work is situated in the field of virtual distance education and more specifically in one of the technologies, whose use has increased exponentially. They are the recommendation systems, which are now used in education as a complementary support in the platforms designed to provide learning resources in a more personalized way. The way in which students perceive, codify, remember, understand and solve problems is different between each one. This task has proved a real challenge, both logistic and theoretical, and the arrival of new information technologies is emerging as the most promising option to project and carry it out. The investigations that have been carried out specifically in the subject show a very marked methodological problem. The way in which its effect has been evaluated, especially in relation to the learning process, has not been from any point of view, rigorous or exhaustive. In general, they only resort to obtaining opinions from students about how they perceive that the use of such systems benefited this process. It seems important to know in greater depth and precision the way in which learning is enhanced with this specific form of technology.
Satisfacción del clima organizacional del bachillerato en profesores de educación física
Authors: Morquecho-Sánchez Raquel , De León-Alcerreca María Fernanda , Rodríguez-Castro Mónica Cecilia , Berruecos-Licona Patricia
Published: September 2020

Human resources is a key point for organizations, the correlation of job satisfaction and organizational climate are important indicators. There are numerous studies that evaluate student satisfaction by referring to physical education; However, few studies focus on the satisfaction of the physical climate of the physical education teacher, which is a factor that impacts educational quality. For this reason, the objective of this study is to evaluate the satisfaction of the organizational climate of physical education teachers in the upper middle level. A descriptive-correlational study, of transversal type, is presented. The "Questionnaire for the analysis of the perception of the satisfaction of the working environment in organizations" was used for data collection. The study participants were 43 professors who teach the subject of physical culture and health of the upper middle level of the UANL. Among the most significant results, there is a high satisfaction (70%) determined by the physical conditions of the job; in relation to the sports equipment available for carrying out activities, the satisfaction was of acceptable level (55%) but not high as expected; When making a correlation with the organizational climate, we observe that the indicators of teamwork, communication and distribution of workloads are at a medium level (46%), influenced by the low participation of workers in cultural and recreational activities. In conclusion, sports managers must have as an important factor the satisfaction of the organizational climate. Our results agree that managers must promote synergy among workers of all levels that encourages greater satisfaction of the organizational climate.
Estudio comparativo de opinión de adolescentes sobre Educación Sexual en instituciones públicas y privadas
Authors: Pacheco-Arenas Noelia , Mercado-Mojica Alin Jannet , Hernández- Maqueda Martha Soledad
Published: September 2020

In Mexico, adolescents receive sexual education from basic education, however, not all adolescents understand the knowledge they need to know to make decisions in relation to their sexual life, so the rate of unwanted pregnancies and sexually transmitted infections (STIs) ) continues to rise. Given this scenario, Social Workers, like other professionals, must assume the commitment to implement sexual education actions for the prevention of pregnancy at an early age, sexual and reproductive health and the promotion of sexual rights, so that the interest of carrying out a comparative study on the opinion of adolescents from two public and two private educational institutions in the City of Poza Rica, Veracruz, about their sexual education. The study presents results obtained through the application of an instrument consisting of 29 questions focused on knowing the opinion of adolescents about their sexual education, contraceptive methods and teenage pregnancy. The objective of the research is to know the perspective of the students of two private and two public educational institutions on sexual education and teenage pregnancy, to establish proposals on a comprehensive Sexual Education.
Brindar soluciones tecnológicas personales y empresariales como una necesidad para incrementar la Cultura de Seguridad Informática
Authors: Barroso-Barajas Alfonso José , Villagran-Vizcarra Dafnis Cain , Ramírez-Ochoa Dynhora Danheyda , Córdova-Villegas Perla Cristina
Published: September 2020

Currently, the number of cyber-attacks is increasing because of the lack of culture of computer security. This is the main cause of this problem. Apart from this, there is a difficulty of finding centralized, clear and practical information for the staff, thus it generates the risk of access controls and vulnerabilities so personal data and company’s information is exposed. That is why it is important to have a place where support is provided, the information is concentrated and offers answers to increase computer security, using a format that is clear enough for all people who access to such information. This is also a business tool that detects vulnerabilities and threats, offering proposals for technological solutions. Objectives: To reduce the risks of insecurity through a Culture of Information Security to guarantee the confidentiality, integrity, speed and availability of information. To analyze security vulnerabilities that may exist in the management of information and systems that affect personally or professionally. To establish awareness mechanisms for staff on IT security issues. To centralize information on the topic of computer security through a website that serves to disseminate attack prevention techniques and possible solutions to computer security vulnerabilities. To streamline the application of surveys through an app that serves to provide technological solutions to the institutions that are surveyed. Methodology: The project is based on comprehensive research, since it explains the vulnerabilities and threats that may occur, predicting the risk and impact that it might generate as well as proposing a solution to increase the degree of computer security. Carrying out a hypothetical-deductive research describing the processes performed and those that are planned in the objective of study, it is pretended to demonstrate that a computer culture can reduce the risks of security in a company and in the society. The type of research techniques used are questionnaires, for this reason series of questions are designed to determine the computer security at the user level. Contribution: A mobile application is developed to carry out the surveys showing statistics in graphs in order to provide technological solutions for the companies. Therefore, the statistical data is reflected on one of the sections of the website developed, where also shows tips, techniques and methodologies to increase security in homes and businesses.
Desarrollo y programación de señales de conmutación para inversor trifásico basadas en técnicas SPWM e implantadas en una FPGA
Authors: Chavarría-Domínguez Benjamín , Chavarría-Domínguez Fernando , Jimenez-Silva Isidro , Alvarez-Martinez Luis
Published: September 2020

The inverters allow us to convert direct current into alternating current with a sine waveform. This work uses the Matlab-Simulink program to develop from a graphic and block environment a SPWM (Sinusoidal Pulse Width Modulation) modulation technique that allows generating the switching pulses of a three-phase inverter based on bridges H, a simulation of the pulses applied to the inverter is also performed to record the voltage at the output of the inverter. Finally, a programming method based on the Icestudio environment is shown to integrate and be able to physically generate the pulses from an FPGA (Field-programmable gate array). The value of this work lies in the detailed description of the procedures necessary to develop the programming of the SPWM modulation that generates the switching pulses and their integration into the FPGA.
Propuesta didáctica para el estudio de la derivada y la integral mediante la resolución de problemas contextualizados y la integración de las Tecnologías de la Información y las Comunicaciones
Authors: Abreu-Toribio Luis Alberto , Carrillo-Córdova José Francisco , Peralta Jiménez José Ramón , Valenzuela-Córdova Florelis
Published: September 2020

The work deals with the study of the derivative and the integral based on the introduction of contextualized problems and the integration of ICT. The objective is to present a didactic proposal focused on the resolution of contextualized problems and the integration of mathematical assistants for the improvement of the teaching-learning process of Differential and Integral Calculation. The novelty presented by this didactic proposal is based on the work with contextualized problems and the integration of ICTs into the teaching-learning process, creatively applied in the study of the derivative and the integral for the training of engineers. The practical significance is manifested in the didactic proposal, since through its application the teaching-learning process was developed in a way that allowed the students to appropriate the contents taking advantage of the resolution of contextualized problems, and the integration of mathematical assistants what promoted a participatory, reflective and contextualized process improving student results.
Diagnóstico de TI en las MPyMES de la región Huasteca Hidalguense
Authors: Felipe-Redondo Ana María , Mendoza-San Juan Luis Alberto
Published: September 2020

The objective of this study is to identify the areas of opportunity for micro, small and medium enterprises (MPyMES) in the Huasteca region of Hidalgo, which can be optimized through the use of IT. An exploratory and descriptive investigation was carried out, with a quantitative approach through the Malhotra methodology,Three ways were raised with respect to the use of ITs, the MPyMES. Why don't they use IT? If they use IT, in what processes do they use them? What other processes through IT can be strengthened ?, the research results reveal that some of the MPyMES do not incorporate IT, because they consider that its implementation is expensive, additionally there is no experience to implement it.This study intends on the one hand, identifies all areas of opportunity in the area of ITs presented by MPyMES and on the other hand serves this information as an element of entry to the CATI Academic Body, for the management of their movements that have those aspects that impact on microenterprises, thus fulfilling the social commitment that as a group of researchers has with society.
Diseño de un sitio web dinámico para institución educativa
Authors: Vázquez-De Los Santos Laura Cristina , Cortes-Morales Griselda , Valdez-Menchaca Alicia Guadalupe , Martínez-Perales Diego Arnulfo
Published: September 2020

The objective of this article is to design a website for an educational institution with a dynamic data model that allows you to easily add, edit and update information. In the methodology, systems engineering concepts will be used during the system development process, documenting each stage. Carrying out the stages of requirements analysis and data model design, considering the parties involved. The Entity Relationship model was designed with the purpose of confirming the logical needs of the information. In addition, the relational model was created, where the attributes of each entity are detailed. MySQL was used as the database management system. Part of the design of the data model includes the way in which it interacts with it, for this the CRUD system is used. With the design of the data models: logical and database models, the script for the creation of the dynamic database was created, which will be used to store all the information relevant to the educational institution. As a result, the correct functionality of the database was guaranteed on the website.
El concepto de la resiliencia a través de la historia
Authors: Gómez-Esquivel Dulce Areli , Moreno-Aguirre Alma Janeth , Cruz-Abarca Laura , Ortiz-Rodríguez María Araceli
Published: September 2020

This research aims to illustrate the importance of resilience throughout history and how it has been taken into account by different authors in the most unfavorable social scenarios, as well as offering a theoretical contribution from it, by different authors. At present, resilience has been proposed as a topic that is attractive in the eyes of researchers, however, it is pertinent to know where this word comes from, which now stands as a capacity developed by human beings who manage to get out. Forward after multiple adversities, their notions are varied, but usually fall in the same direction "people who manage to get ahead after adversity”.
Región y patrimonio biocultural de los ch’oles de Tacotalpa, Tabasco
Authors: Morales-Valenzuela Guadalupe , Villegas-Ramírez María Isabel , Carrillo-Contreras Jaime , Jiménez-Arano Carlos Martín
Published: September 2020

The objective of this work was to define and characterize the region occupied by the Ch’oles de Tacotalpa, Tabasco, as well as identify their biocultural heritage. To delimit the region, the criterion of localities with more than 40% of speakers of the CH’ol language and the ejido nuclei occupied by these localities was considered. The characterization of the region was carried out by review of secondary sources and interview, and identification of the biocultural heritage through interviews and observation. The region is made up of 31 localities in 22 ejido cores with an area of 22,414,791 hectares. 79.43% of the inhabitants of the towns that make up this biocultural region speak the CH’ol language and maintain customs and traditions related to Catholicism and ancestral practices. The environmental situation in this region is related to natural resources and culture. The economy of this region is focused on agricultural activities, basically in the production of the cornfield and the growth of cattle and monocultures (palm oil and teak). The biocultural heritage of the region is represented by traditional agriculture, traditional medicine, use of natural resources and dances and rituals.
Patrimonio biocultural de Tabasco: elaboración de platillos tradicionales en comunidades indígenas
Authors: Carrillo-Contreras Jaime , May-Arias Elsi Margarita , Mazón-Pérez Silvia Gertrudis
Published: September 2020

The objective about this research was to identify the traditional dishes in the municipality from Centla and Tacotalpa that belongs to the territory of Tabasco for recognizing the biocultural heritage at indigenous areas. This survey was developed since 2016 to 2018 and the way of study and methodology was cualitative through the open interviews to people who cooks traditional dishes in order to have a selection of chefs were in charge the plates. This selection was performed with persons related to the students of turistic development career in this case families, relatives and acquaintancies. The interviews were recorded in a mobile divice and transcribed to a Word processor in order to add this information in a data base. The final results show that were 69 dishes distributed in the following way: The municipality of centla obtain 40 rescued recipes and the municipality of Tacotalpa obtain 29 recipes and two of them were identifying in indigenous language as Zoque. The interaction between nature resources and the biocultural heritage for the municipality of centla they were mainly with the wildlife as crustaceans, chelonians, reptiles and fishes so for the mountain area Tacotalpa can be found plants, mammals, gasteropods and fishes.