bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Tuberculosis upon Patients' Quality of Life Who Undergo Directly Observed Treatment Short Course (DOTS) in AL-Amarah City
Authors: Nagi Arkan Bahlool , Shamkh Saad sabri
Published: April 2023

Objective: To find the impact of Tuberculosis disease upon quality of life of patients who undergo Directly Observed Treatment Short Course (DOTS). 
Methodology: A descriptive design is carried out at Respiratory and Chest Diseases out Patients' Clinic, of Nov 20th, 2012 to July 11th, 2013, in order to find out the impact of tuberculosis disease upon quality of life of patients who undergo Directly Observed Treatment Short Course (DOTS). A non-probability (Purposive) sample of (60) Tuberculosis patients. The data collection process has been performed in February 13th, 2012 to the April 6th, 2012. The data were described analyzed through the use of descriptive statistics such as (frequencies, percentage, mean of score and comparative significant) and inferential statistics such as (Chi-square, and T-test).
Results: The results of the study showed that Tuberculosis negatively influence upon patients quality of life domains.
Conclusion: The study concludes that the maximum effect of presented by the social domain, followed by the psychological, level of independency, then the physical domain. While the minimum impact, presented by spiritual domain, followed by the environmental domain.
Recommendation: The study recommended that necessary to do a health educational programs to increase health awareness among peoples who attendants the outpatient clinics and special health centers for tuberculosis disease, as well as the use of mass media by the health authorities.
The Effect of Monosodium Glutamate Ingestion on Spatial Memory and Cognitive Behaviour in Wistar Rats
Authors: Ajah Austin A. , Hart Victor Opuada
Published: April 2023

Monosodium glutamate (MSG), one of the most widely used food-additives in commercial foods gives a special aroma (umami) to processed foods. It’s vital to brain metabolism and function. Adverse effects of MSG have been widely reported. However, there is scarcity of literature on the action of MSG on spatial memory and cognition. Hence, there is need to assess the effect of MSG ingestion on spatial memory and cognitive behavior in Wistar rats. 25 Wistar rats were randomly selected into five groups and treated for three weeks thus: Group 1 (control), Group 2 (0.7 mL MSG), Group 3 (1 mL MSG), Group 4 (1.5 mL MSG) Group 5 (0.1 mL Epinephrine). Neurobehavioral (Barnes, navigation, and handgrip) activities exhibited by the various groups were recorded and analyzed using ANOVA. In the Barnes maze test, there was a significant decrease (p<0.05) in escape time in group 4 when compared to the control for weeks 1 and 3. In week 1 of the Navigation maze test, group 4 animals spent less time (p<0.05) to navigate the maze when compared to the control. In week 1 and 3 of the handgrip test, animals in groups 2, 3 and 5 had a significant decline (p<0.05) in grip strength when compared to the control group; However, in week 2, only the animals in group 5 had a decline in grip strength (p<0.05) when compared to control. MSG did not cause any form of neurotoxicity, cognitive or motor decline in rats.
A Study of Website Translation to Promote the Spread of Local Culture --Taking the Example of Baoding, China
Authors: Zheng Xinran , Zhang Yukui , Song Mengting , li Jiayao
Published: April 2023

Tourism plays a significant role in the development of a city, thus, tourism translation through websites plays an irreplaceable role in promoting local cultural publicity. This paper aims to study ways to promote the dissemination of local culture through three parts: literature review, Analysis of website construction and translations of Ancient City Culture. It analyzes the current construction situation of Baoding’s related websites, pointsing out their current shortcomings, while putting forward various suggestions. In addition, from the perspective of translation, the defects in the translation content of current websites has been pointed out from three perspectives: historical stories and ancient literature, proper nouns, natural scene, and providing corresponding revised translations and methods and suggestions for the translation of this type of text.
Prediction of pulmonary gas exchange disorders in patients with long-term COVID-19 using machine learning methods
Authors: Savushkina O. I. , Astanin P. A. , Kryukov E. V. , Zaicev A. A.
Published: April 2023

Introduction. Hospital discharge after COVID-19 does not mean a complete recovery.

Aim. To predict lung gas-exchange impairment in patients after COVID-19-associated pneumonia.

Materials and methods. An observational retrospective cross-sectional study was conducted. 316 patients (78% men) with long-term COVID-19 and postCOVID computed tomography (CT) changes, without lung diseases in history were enrolled. Spirometry, body plethysmography, diffusion test were performed.

Results. In whole group the medians of ventilation parameters were within the normal ranges. However, 78 (25%) patients had a restrictive type of ventilation disorders, 23 (7%) had airway obstruction, and 174 (55%) had a decrease in diffusion capacity of the lungs (DLCO). The general group was divided into two subgroups depending on the DLCO value: subgroup 1 – DLCO is within the normal range and subgroup 2 – DLCO is reduced. The DLCO analysis between the subgroups showed statistically significant differences in duration from the COVID19 onset (lower in subgroup 2) and in the computer tomography abnormalities in the acute period of COVID-19 (CTmax) (more in subgroup 2) whereas there were no differences in gender, age, body mass index (BMI). Analyzing the odds ratio showed that the chance of a decrease in DLCO after COVID-19 increased 6.5 times with CTmax of more than 45%, 4 times with a duration from the COVID-19 onset less than 225 days, 1.9 times if the age is younger than 63 years while male gender and BMI did not have an impact on DLCO in the post-COVID period. The logistic regression model with identified predictors demonstrated the accuracy, sensitivity and specificity of 81%, 82%, 80%, respectively.

Conclusion. According to our model CTmax of more than 45%, the duration from the COVID-19 onset less than 225 days, age younger than 63 years are important predictors for reducing DLCO after COVID-19.
Characteristics of changes in the coronary arteries in patients with acute coronary syndrome on the background of chronic obstructive pulmonary disease
Authors: Menshikova I. G. , Magalyas E. V. , Sklyar I. V.
Published: April 2023

Aim. Study of the nature and characteristics of changes in the coronary bed in patients with acute coronary syndrome (ACS) and chronic obstructive pulmonary disease (COPD).

Materials and methods. The study included 85 patients with ACS: group 1 included 47 patients with ACS and COPD, group 2 included 38 patients with ACS. All patients underwent a comprehensive clinical, instrumental and laboratory examination.

Results. In the majority of patients of group 1 (76.6%), two- and three-vessel lesions of the coronary bed were revealed, and arterial stenoses were multiple, located mainly in the middle and distal parts of the arteries. In (76.3%) patients of the 2nd group, one- and two-vessel lesions of the coronary bed with localization of stenoses mainly in the proximal and middle segment of the coronary arteries (CA) were revealed. The total number of stenosis and hemodynamically significant stenosis was higher in group 1 compared to group 2 (p=0.01). Extended stenoses were more common in group 1 patients (p=0.04). Damage to the CA of the 2nd order was also higher in the 1st group of patients (p=0.01). The 1st group was divided into two subgroups: 1A (26 people) − patients with COPD of moderate severity and 1B (21 people) − patients with severe COPD. In patients of subgroup 1B, a more significant lesion of the coronary bed was noted due to an increase in the total number of stenoses (p=0.02), hemodynamically significant stenoses (p=0.01), localized in the proximal (p=0.04) and distal (p=0.02) segments of the coronary artery, in the branches of the 2nd order (p=0.02), as well as occlusions and critical stenoses of the coronary artery (p=0.02).

Conclusion. The severity of COPD in patients with ACS significantly affects the number of hemodynamically significant proximal and distal stenoses, as well as branches of the second order coronary arteries, which reduces the effectiveness of surgical treatment and worsens the prognosis of patients with comorbidities.
Impact of correction of homocisteinemia on clinical outcomes of lung damage associated with COVID-19 coronavirus infection
Authors: Tseimakh I. Ya. , Bogachev D. E. , Kostuchenko G. I. , Mamaev A. N. , Kornilova T. A. , Shemyakina I. S. , Tseimakh A. E. , Shoikhet Ya. N.
Published: April 2023

Aim. To assess the effect of serum homocysteine levels on treatment outcomes in patients with COVID19-associated lung damage, depending on the use of folic acid in complex treatment.

Materials and methods. An open, prospective comparative study included 71 hospitalized adult patients with COVID-19-associated lung disease who did not require mechanical ventilation. The main group included 51 patients who received folic acid 15 mg per day in a complex treatment in a fixed combination with pyridoxine hydrochloride and cyanocobalamin. The comparison group included 20 patients in whose therapy folic acid was not used.

Results. The use of folic acid was accompanied by a decrease in serum homocysteine concentration by 2.120 (-0.230; 3.680) µmol/L (p=0.004). When constructing a logistic regression model, the effect of a decrease in serum homocysteine (OR 1.289; 95% CI 1.026‒1.620; p=0.029), methylenetetrahydrofolate reductase MTHFR C677T genotype (OR 10.897; 95% CI 1.240‒95.772; p=0.031) on the achievement of 7th day of hospitalization, the cessation of isolation of SARS-CoV-2 virus RNA from the respiratory tract. Multiple linear regression analysis showed an association between the duration of hypoxemic respiratory failure, determined with SaO2≤93%, with the degree of change in serum homocysteine concentration after treatment, single nucleotide polymorphisms of methylenetetrahydrofolate reductase MTHFR C677T, methionine synthase MTR A2756G and methionine synthase reductase MTRR A66G, initial volume of lung damage ≥50% according to CT data, indicators of D-dimers, C-reactive protein, hemoglobin, platelets, concomitant hypertension, diabetes mellitus (R=0.699; R2=0.489; p=0.005).

Conclusion. The dynamics of the decrease in serum homocysteine after treatment is an important predictor of the cessation of isolation from the respiratory tract of the SARS-CoV-2 virus RNA on the 7th day of treatment, reducing the duration of hypoxemic respiratory failure in patients with lung damage associated with COVID-19 infection.
Peculiarities of phospholipiid changes in erythrocyte membranes in parturient women with COVID-19-associated community-acquired pneumonia
Authors: Ishutina N. A. , Аndrievskaya I. A. , Sinyakin I. A.
Published: April 2023

Aim. To evaluate the phospholipid composition of erythrocyte membranes in parturient women who had COVID-19-associated community-acquired pneumonia (CAP) in the third trimester.

Materials and methods. The material for the study was erythrocytes of peripheral blood of 65 parturient women diagnosed with COVID-19, moderate/severe course, CAP of viral etiology (main group). Patients of the main group, depending on the severity of CAP, were divided into two subgroups: subgroup 1 – moderate course of pneumonia (n=33), subgroup 2 – severe course of pneumonia (n=32). The control group consisted of 35 healthy parturient women. The quantitative composition of phospholipids was studied by two-dimensional thin-layer chromatography according to Kirchner.

Results. In subgroup 1, the concentration of phosphatidylethanolamine and phosphatidylcholine in erythrocyte membranes was below the standard values by 38% and 29%, respectively (p<0.001), in subgroup 2, these indicators decreased by 32% and 48%, respectively (p<0.001). At the same time, a significant increase in the concentration of lysophosphatidylcholine was found in patients of subgroup 1 by 92% (p<0.001) and in patients of subgroup 2 by 110% (p<0.001), compared with the group of healthy individuals. In addition, structural changes in the lipid bilayer of erythrocyte membranes under conditions of COVID-19associated CAP were characterized by a pronounced increase in the concentration of minor fractions of phospholipids: phosphatidylserine and phosphatidylinositol in subgroup 1 by 63% and 53%, respectively (p<0.001), in subgroup 2 by 79% and 68%, respectively (p<0.001), compared with similar indicators in the control group.

Conclusion. With COVID19-associated CAP in maternity women, structural disorganization of the phospholipid components of erythrocyte membranes is determined, manifested by a decrease in the concentration of phosphatidylethanolamine and phosphatidylcholine with a simultaneous increase in the level of lysophosphatidylcholine, phosphatidylserine and phosphatidylinositol. These disorders increase with increasing severity of pulmonary inflammation. The revealed changes in the lipid spectrum of peripheral blood and the composition of erythrocyte membrane phospholipids in COVID-19-associated CAP indicate the need to develop methods for their correction.
ТИТРОВАНИЕ СИЛЬНОЙ КИСЛОТЫ И СИЛЬНОГО ОСНОВАНИЯ. ВЫЧИСЛЕНИЕ рН РАСТВОРА В ПРОЦЕССЕ ТИТРОВАНИЯ
Authors: Сириева Я.Н. , Сириева Т.А.
Published: April 2023

Получены расчетные точки титрования от нулевой точки до получения значения после достижения эвтектического результата сильным основанием и сильной кислотой. Использованы для расчета рН формулы, проведен детальный анализ проведения каждой точки. Приведены формулы различных индикаторов. Интервал перехода окраски выбранного индикатора совпадает со скачком рН или рТ, наблюдаемым в данной системе, а его значение с рН в точке эквивалентности.
ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ СТУДЕНТОК ПО СЕЗОНАМ ГОДА
Authors: Анзоров В.А. , Батиева Э.С. , Индербаева А.Ш.
Published: April 2023

Статья посвящена изучению влияния сезона года на функциональное состояние сердечно-сосудистой системы девушек. Анализ результатов проведенных нами исследований показал, что уровень ПД, АДсрдин, МОК, ОПСС, КЭК и КВ подвергается значительным изменениям по сезонам года. Уровни ЧСС, систолического и диастолического давлений крови, постепенно увеличиваясь, с величин летнего сезона – 76,6 ударов в минуту, 111,4 и 72,8 мм рт. ст. достигли пика – 80,6 ударов в минуту, 125,0 и 79,9 мм рт. ст. соответственно зимой. Наибольший уровень пульсового давления крови – 45,1 мм рт. ст., артериального давления средне динамического – 98,8 мм рт. ст. и КЭК – 3646 у девушек выявлен в зимний период года, а минимальный в летний сезон года – 38,6 мм рт. ст., 89,0 мм рт. ст. и 2967 соответственно. Самая низкая величина СОК – 63,8 мл выявлена у девушек зимой, а высокая – 67,0 – весной. Наибольшая величина МОК – 5,24 л/мин определена у студенток зимой, а наименьшая – 4,98 летом. Среднее значение ОПСС подвергалось постепенному увеличению с весеннего сезона – 1357 по зимний сезон – 1475. Величина коэффициента выносливости – 17,9 была определена у девушек весной и зимой, а 19,8 – в летний период года.
ПОЛОВОЗРАСТНЫЕ ИЗМЕНЕНИЯ УРОВНЯ ГЛЮКОЗЫ В КРОВИ ЖИТЕЛЕЙ ЧЕЧЕНСКОЙ РЕСПУБЛИКИ
Authors: Джамбетова М.О. , Солтаева Х.Х. , Магомедова З.А.
Published: April 2023

В работе выполнено экспериментальное исследование концентрации глюкозы в капиллярной крови у лиц мужского и женского пола разного возраста. К исследованию были привлечены жители Чеченской Республики. Испытуемые были разделены на несколько групп: по полу и возрасту. Исследовали возрастные и половые различия уровня сахара в крови. Исследование глюкозы проводили с помощью портативного глюкометра, строго натощак, в утренние часы. Было выявлено, что уровень глюкозы в возрастном интервале от 11 до 60 лет имеет статистически значимые различия. В то же время в различных возрастных группах (подростковый период, юношеский, зрелый возраст) половые различия по уровню сахара отсутствовали.
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ БАКТЕРИЙ ESCHERICHIA COLI, ВЫДЕЛЕННЫХ У БОЛЬНЫХ В РКБ ИМЕНИ Ш.Ш. ЭПЕНДИЕВА
Authors: Батаев Х.М. , Авдуев И.С.
Published: April 2023

В статье приведены данные об антибиотикорезистентности бактерий вида Escherichia coli, выделенных у 54 больных с предварительными диагнозами «Острый цистит» и «Хронический цистит» к 15 антибактериальным препаратам. В ходе проведенного исследования бактерии Escherichia coli проявили различную чувствительность к разным антибиотикам.
The Gift of Sanctions: An Analysis of Assessments of the Russian Economy, 2022 – 2023
Authors:   James K. Galbraith holds the Lloyd M. Bentsen, jr. Chair in Government/Business Relations at the Lyndon B. Johnson School of Public Affairs, The University of Texas at Austin. A former Executive Director of the Joint Economic Committee of the US Congress with a PhD in Economics from Yale, he is an elected member of the Accademia Nazionale dei Lincei, the Lisbon Academy of Sciences, and the Russian Academy of Sciences, and of the Free Economic Society of the Russian Federation., Galbraith James K.
Published: April 2023

This essay analyzes a few prominent Western assessments, both official and private, of the effect of sanctions on the Russian economy and war effort. It seeks to understand the main goals of sanctions, alongside bases of fact and causal inference that underpin the consensus view that sanctions have been highly effective so far. Such understanding may then help to clarify the relationship between claims made by economist-observers outside Russia and those emerging from sources inside Russia – notably from economists associated with the Russian Academy of Sciences (RAS) – which draw sharply different inferences from the same facts. We conclude that when applied to a large, resource-rich, technically proficient economy, after a period of shock and adjustments, sanctions are isomorphic to a strict policy of trade protection, industrial policy, and capital controls. These are policies that the Russian government could not plausibly have implemented, even in 2022, on its own initiative.
PERCEPTION OF INFORMATION BY THE ART-MARKET AUDIENCE
Authors:   Environmental Safety Development Fund, Moscow, Russia, Ozerskaya Olga P.
Published: April 2023

The article deals with the informational characteristics of art objects and the patterns of their perception by the audience. The logic of the article is based on the paradigm according to which the art market is informational in nature and the consumer properties of art objects largely depend on the nature of the audience’s mastering the information at its disposal. Based on the content analysis of specialized literature and trends in the development of the art market, the article outlines approaches to the structuring of the category “culture of information perception”; a classified set of various aspects of the perception of art objects by the audience is given. The concept of “culture of information perception” is interpreted as an immanent characteristic of the audience of institutions, characterizing the rationality and optimality of the process of mastering information. It is emphasized that the multidimensionality and multifactorial nature of the developed concept predetermine the fundamental openness of this category for further discussion and definition of its essential characteristics.
MAIN MECHANISMS FOR INVOLVING INTELLECTUAL PROPERTY IN COMMERCIAL TURNOVER
Authors:   All-Russian Research Institute of Experimental Physics, Zhigalov Vladimir I.
Published: April 2023

The modern economy, when creating new technologies, innovative solutions, requires effective implementation in the real sector, ensuring the development and formation of the country’s gross domestic product (GDP). The created intellectual property should not settle as a dead weight in formal registries. In this paper, the problems of commercialization of intellectual property in Russia are analyzed and effective options for implementing this process are proposed. Trends in the creation of intellectual property, its reflection as intangible assets and its inclusion in commercial circulation are analyzed.
IMPACT OF THE INNOVATIVE PROJECT ON THE FINANCIAL STATE OF THE ENTERPRISE
Authors:   Saint Petersburg State University of Aerospace Instrumentation, Loseva Olga S. , Molchanova Regina V. ,   Saint Petersburg State University of Aerospace Instrumentation
Published: April 2023

The impact of innovative technologies on the transformation of general and particular indicators consists in an integrated approach of factors and causes that negatively affect the efficiency of the analyzed object. The purpose of the study is to substantiate the impact of the implementation of innovative projects on the financial condition of the enterprise in conjunction with the change in the general and particular indicators of the company’s activities. Making a decision on the feasibility of an innovative project to identify the relationship between the performance indicators of financial and innovative activities provides for the compliance of the level of development of project solutions with the requirements of institutional investors and the identification of reserves for increasing the economic efficiency of an enterprise by determining the degree of impact of innovations on changing the main performance indicators. The presented technique makes it possible to control the effectiveness of the use of material, financial, labor resources when making a managerial decision by conducting a comprehensive assessment using deterministic factor models. As a discussion on the article, it can be stated that the effective management of factors that have a significant impact on generalizing and particular indicators makes it possible to systematize theoretical issues and integrate them into the general system of indicators of companies. Determination of the integral indicator of the effectiveness of innovative activities in the implementation of an innovative project can be used to determine the relevance of managerial decisions and a qualitative assessment of the enterprise’s activities.
SMART MANUFACTURING AND RELATED COMPLEXITIES AND RISKS
Authors:   Saint Petersburg State University of Aerospace Instrumentation, Trofimova Nataliya N.
Published: April 2023

This article discusses issues related to the key risks of smart manufacturing. In this context, such aspects as standardization, information security, availability of IT infrastructure and fast Internet are analyzed. The key factors that can cause organizational and financial risks at the stage of transition to smart production are considered.
PENDIDIKAN SEKS BAGI ANAK USIA DINI DI DESA SATAR LENDA, KECAMATAN SATAR MESE BARAT, KABUPATEN MANGGARAI
Authors: Gervasius Adam
Published: April 2023

Pendidikan Seks bagi Anak Usia Dini di Desa Satar Lenda, Kecamatan Satar Mese Barat, Kabupaten Manggarai. Pengaruh kemajuan teknologi informatika di Indonesia pada satu sisi menjadi suatu kebanggaan, namun di sisi lain menjadi ancaman bagi perkembangan psikologis dan sosial anak. Pada kenyatannya, anak-anak dapat dengan mudah mengakses berbagai informasi tentang hal-hal yang berkaitan dengan seksualitas, juga informasi tentang hubungan seks. Hal itu sungguh memprihatinkan. Keprihatinan lainnya adalah kurangnya pengetahuan dan lemahnya pendampingan orangtua terhadap perkembangan seksual anak-anak. Masyarakat desa Satar Lenda, kecamatan Satar Mese Barat, Manggarai, pada umumnya belum memiliki pemahaman dan kesadaran tentang pendidikan seksualitas pada anak sejak dini. Bagi sebagian orang tua, seksualitas merupakan hal tabu. Pendidikan seksualitas malah dianggap dapat mendorong remaja untuk berhubungan seks. Masyarakat masih memandang pendidikan seks seolah sebagai suatu hal yang vulgar. Bila dikaji secara lebih mendalam mengapa masyarakat enggan membicarakan seks, hal itu disebabkan adanya pandangan sempit bahwa seks berarti ‘hubungan seks’; ada kekuatiran besar terhadap terkait hubungan seks di kalangan anak atau remaja. Anak-anak dilarang keras untuk menyebut salah satu orangan tubuh yang dianggap sangat berharga. Meskipun demikian, hal itu tidak dibarengi dengan penjelasan yang ‘mendidik’ sehingga anak-anak memahami organ-organ reproduksi. Melalui PkM ini, anak usia dini dan para orang tua di desa Satar Lenda, kecamatan Satar Mese Barat, Manggarai, diedukasi terkait dengan pendidikan seksualitas.
Application of Blockchain in Supply Chain Management
Authors: - Sandip Kumar Singh Modak
Published: April 2023

In the rapidly evolving environment of the international supply chain, the traditional network of manufacturers and suppliers has grown into a vast ecosystem made of various products that move through multiple parties and require cooperation among stakeholders. Additionally, the demand for improved product visibility and source-to-store traceability has never been higher. However, traditional data sharing procedures in today’s supply chain are inefficient, costly, and unadaptable as compared to new and innovative technology. Blockchain technology has shown promising results for improving supply chain networks in recent applications and has already impacted our society and lifestyle by reshaping many business and industry processes. In an effort to understand the integration of blockchain technology in the supply chain, the proposed work consists of novel approach to improve the traceability in supply chain through the blockchain technology.
Identificação e Mapeamento de Áreas Infestadas por Capim-annoni (Eraglostis plana) Através do Uso de Índice de Vegetação no Município de Dom Pedrito/RS
Authors: Farinha Cristhiane Madruga , Hanke Daniel , Nascimento Shirley Grazieli da Silva , Ávila Mariana R. de , Deble Leonardo Paz
Published: April 2023

O Eraglostis plana Ness, popularmente conhecido como Capim-annoni, é considerada hoje uma espécie invasora de difícil erradicação dos campos sulinos. O objetivo deste trabalho é avaliar a possibilidade de uso das técnicas aerofotogramétricas como forma de identificação dadistribuição do Capim-annoni, de maneira a contribuir no monitoramento da referida planta. Para este trabalho foram realizadas a coleta de informações relativa à presença ou não de Capim-annoni a campo, a análise de Índice de Vegetação, a altura de planta e a condutividade elétrica do solo. Os resultados apresentados mostram que o Índice é uma ferramenta promissora na identificação de Capim-annoni por sensoriamento remoto.
Jatamansi (nardostachys jatamansi): insight of its morphological, Ethno-pharmacological and therapeutical aspect
Authors: Mohammad Ehsan , Kushwaha Ashwini Kumar
Published: April 2023

Plants have been use for the treatment, mitigation and cure of the disease since time immemorial. The natural recourses are considered as safe for human use. Ayurveda advocates the Jatamansi in various human ailments. In the present review article we tried to establish the morphological, ehno-pharmacological and therapeutic aspect of the Jatamansi. The various search engines like, Google scholar, EMBASE, pub med, pub med central are used to search the literary information and published article. We tried to put the facts that are demand of this article and explore the proficiency of the Jatamansi as panacea for various ailments.
The Relationship between Dickkopf-Related Protein-1 (DKK-1) Plasma Levels and Impaired Cognitive Function in HIV Patients
Authors: Trisna Yulia , Yuliarni Syafrita  , Restu Susanti
Published: April 2023

Background: Dickkopf-related protein – 1 (DKK-1) is an antagonist protein to the Wingless (Wnt)-β catenin signal. Dysregulation of Wnt-β catenin signaling by DKK-1 causes disruption of neuronal synapses, which can result in impaired cognitive function. Impaired cognitive function in people with HIV or HIV-associated neurocognitive disorder (HAND) is a spectrum of cognitive disorders related to HIV neuroinvasion and neuroinflammation, which significantly results in impaired cognitive function and daily activity. This study aimed to assess the relationship between plasma DKK-1 levels and impaired cognitive function in HIV patients.

Methods: This study used a cross-sectional design, consisting of 84 HIV sufferers who went to the voluntary counseling and testing (VCT) polyclinic at Dr. M. Djamil General Hospital, Padang, Indonesia, in the period December 2022 - March 2023, who met the inclusion and exclusion criteria. Cognitive function was assessed using the Montreal Cognitive Assessment Indonesian version (MoCa-Ina), and daily activity function using the instrumental activity of daily living (IADL) examination. Plasma DKK-1 levels were measured using the enzyme-linked immunosorbent assay (ELISA) method.

Results: The mean plasma DKK-1 level of HIV sufferers was 358.4 (+ 157.6) pg/mL. ANI type disorder was found in 78.6%, MND in 21.4%, and no HAD type. There was a significant relationship between plasma DKK-1 levels and impaired cognitive function in HIV patients (OR = 2.82, CI95% = 1.128-7.043, p = 0.025), but there was no significant difference in plasma DKK-1 levels between types of cognitive impairment ANI and MND (p = 0.858).

Conclusion: Plasma DKK-1 levels are significantly associated with impaired cognitive function in HIV patients.
Determinants of Control over Usage of Women’s Cash Earnings in the Households of Rural Areas: A Case of Wanging’ombe District Council in Tanzania
Authors: Chengula Miriam , Mkelenga Amani Joseph , Mpeta Innocent Fabiano
Published: April 2023

The study was conducted in the Wanging’ombe district council in the Njombe region, Southern highlands of Tanzania. The objective of the study was to assess the determinants of women’s control over their earnings. The study employed a cross-section research design. Data were collected from 150 women who engaged in various economic activities. The structured interview method was used to collect data using a structured questionnaire. Data were processed and analysed using IBM SPSS statistics version 20 and Stata version 11. The analysis involved descriptive analysis in exploring the characteristics of women in the study area, a chi-square test for association, and a binary logistic regression to explore the predictors. The results revealed that more than half (54.7%) of women reported that their husbands/partners decide for them on the use of money earned. Three factors, namely ownership of the house, kind of earning activity (source of income), and amounts of money earned per month are predictors of the control over women’s cash earnings in the household. The study concluded that, although husbands have less chance to decide on income earned by women who engage in economic activities other than farming and those who earn a higher income, household resources including women’s earnings are controlled by husbands to a large extent. The local government authorities in Wanging’ombe and non-government organisations interested in women’s empowerment should intensify efforts to address violence against women, especially economic abuse. This will enable women to engage in different economic activities and be employed in informal and formal sectors
Pengaruh lama waktu inkubasi, konsentrasi starter terhadap pH, viskositas dan sifat organoleptik yoghurt susu sapi
Authors: Adiputra Rachmat , Ramadiyanti Mita , Ulfah Triana , Maesaroh Dini Islah
Published: April 2023

This research was conducted to determine the effect of incubation time and starter concentration on pH, viscosity, and organoleptic properties of cow's milk yogurt. This research was conducted from 16 to 23 June 2019 located at FIYO Yoghurt owned by Mr. Engkos Zakaria which is located in Pameungpeuk Village RT 03 RW 12 Pasirhalang Village, Cisarua District, West Bandung Regency. This study used a completely randomized design (CRD) factorial design consisting of two factors and three replications. The first factor is the length of incubation time (W) consisting of three levels, namely w1 = 3 hours incubation time, w2 = 6 hours of incubation time and w3 = 9 hours of incubation time. The second factor is the starter concentration (S) consisting of 3 levels, namely s1 = 2% starter concentration, s2 = 4% starter concentration and s3 = 6% starter concentration. From the research results it can be concluded that there has been an interaction between the length of incubation time and the concentration of the starter on the viscosity of cow's milk yogurt. The best interaction occurred at 9 hours of incubation time and 6% starter concentration. 9 hours incubation time and 6% starter concentration had a good effect on pH and viscosity. While the incubation time of 6 hours and 6% starter concentration produced organleptic properties which were quite liked by the panelists
Mesleki Öğrenme Topluluğu ile Okul Yöneticisinin Ders Denetimi Arasındaki İlişkinin İncelenmesi
Authors: EFE Muhammet Zübeyir , ÇOBAN Ömür , GÜN Feyza
Published: April 2023

Bu araştırmanın amacı, okul yöneticilerinin ders denetimi ve sunduğu dönütlerin etkililiği ile mesleki öğrenme topluluğu arasındaki ilişkiyi incelemektir. Araştırma, ilişkisel tarama modelinde betimsel bir çalışmadır. Araştırmanın evrenini, 2020-2021 eğitim öğretim yılında Karaman ilinde görev yapmakta olan 2747öğretmen oluşturmaktadır. Araştırmada okul türü bazında tabakalı örneklem yöntemi kullanılarak 331öğretmen örneklem olarak belirlenmiştir. Veri toplama sürecinde 347 öğretmene ulaşılmıştır. Veri toplama aracı olarak Okul Yöneticisinin Ders Denetimi ve Sunduğu Dönütlerin Etkililiği Ölçeği (OYDD) ve Mesleki Öğrenme Topluluğu Ölçeği (MÖTÖ) kullanılmıştır. Ayrıca öğretmenlerin demografik bilgilerine ulaşmak amacıyla kişisel bilgiler formu hazırlanmıştır. Araştırmanın sonucunda öğretmenlerin okul yöneticilerinin ders denetimi ve sunduğu dönütlerin etkililiği ve okullarının mesleki öğrenme topluluğu olmasına yönelik algı düzeylerinin yüksek olduğu belirlenmiştir. Okul yöneticilerinin ders denetimi ve sunduğu dönütlerin etkililiği ile mesleki öğrenme topluluğu arasında pozitif yönde ve orta düzeyde anlamlı bir ilişki olduğu saptanmıştır. Mesleki öğrenme topluluğunun alt boyutlarından paylaşımcı ve destekleyici liderlik boyutu ile okul yöneticilerinin ders denetiminin etkililiği arasındaki ilişkinin diğer boyutlara göre daha yüksek düzeyde olduğu görülmüştür. Okul yöneticilerinin ders denetimi ve sunduğu dönütlerin etkililiği, mesleki öğrenme topluluğunun tüm alt boyutlarının anlamlı bir yordayıcısı olarak belirlenmiştir. Elde edilen sonuçlardan hareketle okul yöneticilerine paylaşımcı ve destekleyici liderlik davranışları kapsamında işbirlikçi çalışmalarla diyalog ortamı oluşturmaları, eğitim öğretim faaliyetleri ile ilgili dönütler vermeleri ve okulda ortak kararların alınmasını teşvik etmeleri önerilmiştir. Böylece okullarda ders denetimi süreçlerinin daha etkili olacağı düşünülmektedir.
Denetim Uygulamalarının Mesleki ve Etik İlkelere Uygunluğunun İncelenmesi
Authors: DEMİR Serkan , KALE Mustafa
Published: April 2023

Bu araştırmanın genel amacı öğretmen ve okul yöneticilerinin görüşlerine göre denetim uygulamalarının mesleki ve etik ilkelere uygunluğunun incelenmesidir. Araştırma tarama modellerinden durum çalışması (örnek olay tarama modeli) ile gerçekleştirilmiştir. Araştırmada çalışma grubu, Ankara-Çubuk ilçesinde bulunan resmi okullarda görevli ve araştırmaya gönüllü katılan 18 yönetici ve 48 öğretmen olmak üzere 66 kişiden oluşmaktadır. Araştırmada veriler, araştırmacılar tarafından geliştirilen yarı yapılandırılmış görüşme formu ile toplanmıştır. Toplanan veriler içerik analizi yöntemi ile analiz edilmiştir. Görüşme sorularına verilen cevaplardan tema ve kodlar oluşturulmuş, frekans dağılımları belirlenmiştir. Araştırma sonucunda, yönetici ve öğretmenlerin çoğunluğunun görüşüne göre; denetim görevlilerinin “tarafsızlık ve nesnellik, eşitlik, dürüstlük, gizlilik, yetkinlik ve meslekî özen” ilkelerine uygun hareket ettiği tespit edilmiştir. Fakat “çıkar çatışmasından kaçınma, nezaket ve saygı” ilkelerine uygun davranışlar sergilemediği bulunmuştur. Denetim görevlilerinin özellikle onur kırıcı, küçük düşürücü, baskıcı, hakaret ve tehdit edici tavırlarda bulunmamaları, etkili rehberlik hizmetlerine katkı sunacaktır. Ayrıca denetim görevlilerine “etkili iletişim” konusunda eğitimler verilebilir. Denetim görevlilerinin etik dışı davranışlarda bulunmalarını engellemek amacıyla “Denetim Görevlilerinin Uyacakları Meslekî Etik Davranış İlkeleri Hakkında Yönetmelik” kapsamında daha hassas davranmaları ve ilgi yönetmelik maddelerini göz önünde bulundurarak denetim sürecini gerçekleştirmeleri önerilmektedir.
Improving Procurement Selection Criteria for Managing Construction Tender-Price Volatility on Public Projects
Authors: Tembo Moffat , Mwanaumo Erastus Misheng’u , Kahanji Charles
Published: April 2023

This paper investigates current knowledge concerning adopted procurement strategies for managing construction-price in the public sector. The article reveals that studies mainly address four main areas: procurement decision support systems, transparency, ethical considerations in procurement, identification of procurement criteria, and overcoming inconsistencies in the procurement process. The paper provides a new perspective on the selection of procurement strategy. Therefore, selecting a suitable procurement strategy is essential for managing project pricing. The review has revealed that the lowest bid is the main criterion of contractor selection in the public sector. There is a need to combine some, if not all, procurement strategies within a significantly flexible approach that can have multiple potential advantages in the construction field by serving as a robust decision-making tool. There is a need to develop a public procurement strategy for managing construction price variability and inflation by modeling for fundamental principles such as value for money, benchmarking price performance, and reducing tendering documentation errors, that collude and conspire to impact price inflation, client perception and infrastructure push, and public accountability. The study, thus, deduces two principal factors that serve as critical indicators of a procurement selection criterion focused on managing construction tender-price variability and inflation. These include benchmarking price performance and eliminating errors in the tender documentation.
Porter’s Five Forces and Competitive Advantage of Telecommunications Firms in Nigeria
Authors: Umoh Victor A. , Umana Esitime S. , Udoh Martin A.
Published: April 2023

This study was conducted to investigate Porter’s Five Forces and Competitive Advantage of Telecommunications Firms in Nigeria. The survey research design was adopted in the study. The study had a population of 181 and was treated as census study. The primary instrument used in data collection was questionnaire. Two firms, Airtel and MTN were involved in the study. The study made use of the survey research design and achieved 61.38% response rate. Data analysis was done with multiple regression. The study revealed an adjusted R2 of 0.723 which implies that about 72.3% of the variables of Porter’s Five Forces studied when combined will account for about 72.3% changes in competitive advantage in telecommunications firms in Nigeria. Specifically, Buyers’ Bargaining Power (Beta = 2.981, t= 4.785, P< 0.05); Current Rivalry (Beta = 1.003, t= 2.145, P< 0.05); Threat of Substitute (Beta = 1.064, t= 2.011, P< 0.05) and Threat of New Entrant (Beta = 3.138, t= 3.017, P< 0.05) were all significant in influencing competitive advantage among telecommunication firms in Nigeria. However, Suppliers Bargaining power (Beta = 1.372, t= 1.847, P> 0.05). had no significant influence. It was concluded that Buyers’ Bargaining Power, Current Rivalry, Threat of Substitute and Threat of New Entrant were the key forces that influence competitive advantage among telecommunication firms in Nigeria, while Suppliers Bargaining power was weak and therefore, not capable of influencing competitive advantage among telecommunications firms in Nigeria. It was recommended that telecommunications companies in Nigeria should pay close attention to Buyers’ Bargaining Power and strategize on satisfying customers, meeting their needs and retaining their patronage; continuously monitor their competitors, launch aggressive campaigns, provide loyalty programmes and provide appropriate strategic response, strategize on retaining their customers and making difficult for new telecommunications firms to birth in the country; should ensure that their actions and policies do not cause their customers to switch to other brands but influence customer loyalty, in order improve their competitive position.
The Meta-analysis of efficacy and safety of acupuncture in the treatment of stage Ⅱ-Ⅳ pressure ulcers
Authors:   The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Xu ke , Cai Guofeng , Cui Yanan , Gao Ziyin , Sun Manchao
Published: April 2023

Review question / Objective: The subjects were patients who met the diagnostic criteria for stage II - IV pressure ulcers.Interventional factors include various acupuncture treatments, including ordinary acupuncture, peripheral acupuncture, electroacupuncture or fire acupuncture. The course of treatment is more than 10 days.The control group was treated with conventional western medicine for more than 1 days.The main results included the time of complete healing, the time of granulation growth, and percentage of ulcer healed (PUHTP) in the trial period.The main results included the complete healing time, granulation growth time and percentage of ulcer healing (PUHTP), and the total effective rate and average healing time were calculated.The type of study was a randomized controlled trial.
The Hot Main Kuiper Belt Size Distribution from OSSOS
Authors: Petit Jean-Marc , Gladman Brett , Kavelaars J. J. , Bannister Michele T. , Alexandersen Mike , Volk Kathryn , Chen Ying-Tung
Published: April 2023

Using the absolute detection calibration and abundant detections of the Outer Solar System Origins Survey project, we provide population measurements for the main Kuiper Belt. For absolute magnitude H

r
< 8.3, there are 30,000 nonresonant main-belt objects, with twice as many hot-component objects than cold, and with total mass of 0.014 M
⊕, only one-seventh of which is in the cold belt (assuming a cold-object albedo about half that of hot-component objects). We show that trans-Neptunian objects with 5.5 < H

r
< 8.3 (rough diameters 400–100 km) have indistinguishable absolute magnitude (size) distributions, regardless of being in the cold classical Kuiper Belt (thought to be primordial) or the “hot” population (believed to be implanted after having been formed elsewhere). We discuss how this result was not apparent in previous examinations of the size distribution due to the complications of fitting assumed power-law functional forms to the detections at differing depths. This shared size distribution is surprising in light of the common paradigm that the hot-population planetesimals formed in a higher density environment much closer to the Sun, in an environment that also (probably later) formed larger (dwarf planet and bigger) objects. If this paradigm is correct, our result implies that planetesimal formation was relatively insensitive to the local disk conditions and that the subsequent planet-building process in the hot population did not modify the shape of the planetesimal size distribution in this 50–300 km range.
The Empirical Limits of Gyrochronology
Authors: Bouma Luke G. , Palumbo Elsa K. , Hillenbrand Lynne A.
Published: April 2023

The promise of gyrochronology is that, given a star’s rotation period and mass, its age can be inferred. The reality of gyrochronology is complicated by effects other than ordinary magnetized braking that alter stellar rotation periods. In this work, we present an interpolation-based gyrochronology framework that reproduces the time- and mass-dependent spin-down rates implied by the latest open cluster data, while also matching the rate at which the dispersion in initial stellar rotation periods decreases as stars age. We validate our technique for stars with temperatures of 3800–6200 K and ages of 0.08–2.6 gigayears (Gyr), and use it to reexamine the empirical limits of gyrochronology. In line with previous work, we find that the uncertainty floor varies strongly with both stellar mass and age. For Sun-like stars (≈5800 K), the statistical age uncertainties improve monotonically from ±38% at 0.2 Gyr to ±12% at 2 Gyr, and are caused by the empirical scatter of the cluster rotation sequences combined with the rate of stellar spin-down. For low-mass K dwarfs (≈4200 K), the posteriors are highly asymmetric due to stalled spin-down, and ±1σ age uncertainties vary non-monotonically between 10% and 50% over the first few gigayears. High-mass K dwarfs (5000 K) older than ≈1.5 Gyr yield the most precise ages, with limiting uncertainties currently set by possible changes in the spin-down rate (12% systematic), the calibration of the absolute age scale (8% systematic), and the width of the slow sequence (4% statistical). An open-source implementation, gyro-interp, is available online at github.com/lgbouma/gyro-interp.
A new synonym of a species of Stachyotropha Stål, 1871, a genus of Asian Stenopodainae (Hemiptera, Heteroptera, Reduviidae)
Authors: Okuda Kyosuke , Chen Zhuo
Published: April 2023

Stachyotropha Stål, 1871 (Reduviidae, Stenopodainae) currently includes only two species: S. punctifera Stål, 1871 and S. miyamotoi Hidaka & Miller, 1959 only recorded from East Asia.

This study reviews the genus Stachyotropha Stål, 1871 and its two described species. Based on the examination of the type specimens and the original descriptions, S. miyamotoi Hidaka & Miller, 1959 is regarded as a junior synonym of S. punctifera. Further, we briefly discuss the distribution and biology of S. punctifera.
Is it open access if registration is required to obtain scientific content?
Authors: Yamada Yuki , Nishikawa-Pacher Andreas , Teixeira da Silva Jaime A.
Published: April 2023

Some journals require users to register before accessing a scientific paper, despite labelling that content as open access (OA) and free-of-charge. We refer to such cases as members-only OA (MOOA), which we contend is not ‘free’ since users are forced to ‘pay’ with personal data. Scholarly content may be accessible via MOOA to either the in-browser text (HTML) or to the archival-friendly version (PDF), or both. We suggest a four-tier typology to capture the degree of openness based on this observation. We believe that technical guidelines of OA implementation should not permit MOOA.
PEST analysis of the future Chinese vertical farming market: Environmental sustainability and energy savings
Authors: Ning Shuang , Xydis George
Published: April 2023

To provide people with an insight into market development in the Chinese vertical farming (VF) industry, this work has conducted a PEST analysis to identify the external market environment from political, economic, social and technological perspectives. VF is developing at a rapid speed with great market potential and opportunities. Environmental pollution and consumersx increased awareness of a healthy lifestyle drive Chinese people to seek "safety, healthier and clean" food more than anyone else in the world. The increasing gross domestic product enables more and more people to afford VF-produced products. The great market opportunities have attracted many domestic and international investors to join the market. Until 2020, there were more than 200 plant factories operating in China, and the number is increasing. Nevertheless, the development of vertical farms is in the initial stage in China, which can be summarized as follows: 1) the high investment and operational costs are the main barriers to profitability; 2) technology development still lags behind other VF-advanced countries, such as in the development of intelligent crop management equipment; 3) insufficient government support, as promoting a vertical farm market requires more efficient political and financial support from the Chinese government; and 4) consumer public awareness of VF is too low.