bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral health, early childhood and precariousness: an analysis of the barriers and levers to access to care through the experiences of families
Authors: Vabre Alice , Millot Isabelle
Published: August 2024

Oral health is a relevant issue in public health due to the frequency of oral diseases and their impacts on health, social and professional insertion. Most of these affections could be avoided with healthy behaviors and easier use of care. However, social inequalities in health and access to care are present from early childhood. Prevention actions and support in the care pathway adapted to vulnerable populations are necessary in order to improve partnership with families, prevention and access to care from early childhood. This study aims to explore the representations about oral health and oral care from parents of children aged from 1 to 6 years old identified as being in a precarious situation and living in Dijon and its conurbation.

La santé bucco-dentaire est un enjeu majeur de santé publique en raison de la fréquence des affections et de son impact sur la santé générale, la qualité de vie et l’insertion sociale. La plupart des affections seraient évitables par le biais de l’adoption de comportements favorables à la santé ainsi que par un recours aux soins facilité. Or des inégalités sociales en termes de santé bucco-dentaire et de recours aux soins sont présentes dès la petite enfance. Des actions de prévention et d’accompagnement dans le parcours de soins adaptées aux populations en situation de précarité sont donc nécessaires afin d’améliorer le partenariat avec les familles et la prévention et l’accès aux soins dès la petite enfance. Cette étude vise à explorer le rapport à la santé et aux soins bucco-dentaires de parents d’enfants de 1 à 6 ans identifiés en situation de précarité résidant dans l’agglomération dijonnaise.
The Effect of Roll Maintenance Costs on Kiln Machines on the Efficiency of Expenditure on PT. XYZ
Authors: Chaerudin Abdul Rauf
Published: August 2024

PT. XYZ is a company engaged in the ceramics industry. One way maintenance is carried out on production machines is to use the cost of maintenance expenditure which aims to streamline and expedite the production process of both quality and quantity. In this study the cost pemeliharaanyang done is on a production machine roller kiln kiln mainly because if not maintained can quickly roll the kiln was dirty and broken so that it can directly increase the cost of expenditures (the smaller the efficiency of expenditures) for the purchase of a new kiln roll to replace the roll kiln dirty and broken. The method used in this study to determine the effect of roller kiln maintenance costs on the efficiency of spending is a statistic that is a quantitative method with simple linear regression (two variables). From the research results obtained regression equation y = 0.379 +1.110 X diliat coefficients table from SPSS, Efficiency of expenditure will be worth 0.379 if the company no roll maintenance costs. Each one-time increase in the cost of engine maintenance roll kiln then the efficiency corporate spending rose by 1.110. The cost of engine maintenance roll kilns have strong relationships with significant spending efficiency by 97.9% results from SPSS can diliat model summary table, the efficiency of spending can be influenced by other factors is the use of EUT. Average roll kiln is unplugged as much as 105.73 in round roll 106 at a price of Rp 300,000 a roll when not using the average maintenance cost per month can pay for purchases of new roll of 106 x 300 000 = 31.8 million. If using the maintenance costs (usage Grinding stone) at a price of Grinding stones, Rp. 1.800.000 to clean up the dirty roll kiln as many as 100-150 stems roll is clearly more efficient in spending comparedWith no use of maintenance costs
Covid-19 Pandemic: Adaptability of Vocational School Strategic Planning
Authors: Munir Khoirul , Basrowi Basrowi , Suseno Bambang Dwi
Published: August 2024

This research aims to test the adaptability of vocational school strategic planning in the face of the Covid 19 Pandemic.  Along with important aspects of how to adjust in the era of Industry 4.0.  This preparation is in the form of a Strategic Plan guided by SWOT analysis and valuable to vocational schools. This study uses quantitative research methodology and then combined with a descriptive qualitative approach. Data collection is used non-probality sampling with Google Forms and questionnaire devices. A random sample of 30 people was selected as a sample. The school has 15 internal students and 15 external students. The overall index of vocational schools in Cikande District of Serang Regency produced the following findings. The strength is 8.42 points, the Weakness is 5.98 points, the Odds are 8.62 points, and the Threat is 6.70 points. When calculated, the coordinate point of internal analysis worth 2.26 (X) and the coordinate point of external analysis worth 1.92 (Y) are obtained (Y). It was determined that vocational schools in Cikande Sub district were in a position to be classified as Aggressive or Prima in quadrant 1
The Influence of Leadership Democracy, Work Discipline and Work Environment on Individual Employee Performance in PT. Indosino Agrochemical
Authors: Handayani Mega Putri , Nugroho Prayekti
Published: August 2024

This study aims to determine the effect of democratic leadership, work discipline, and work environment on individual employee performance. This type of research is quantitative. The population in this study were employees of PT. Indosino Agrochemical. Data collection is done by distributing online questionnaires to employees, data directly obtained from respondents. The results of this study indicate that (1) democratic leadership has a significant effect on individual employee performance, (2) work discipline has an effect on individual employee performance, (3) work environment has no significant effect on individual employee performance
Awakening Self Awareness to Strengthen Health Protocol Discipline
Authors: Subiyanto Didik , Prayekti Prayekti , Septyarini Epsilandri
Published: August 2024

Background: The high transmission of COVID-19 in Indonesia requires serious handling. The public is also required to be involved in preventing the transmission of Covid-19, through discipline in carrying out health protocols. From the beginning of 2020 until the middle of 2021, the COVID-19 outbreak has claimed many lives and severely hampered human activities in many sectors. The economic and education sectors have felt the negative impact of the COVID-19 outbreak, so it is necessary to conduct research related to strategic prevention efforts.
Objective: The purpose of this study was to determine the factors that can improve the discipline of health protocols, through efforts to increase the self-awareness of the younger generation, especially among students.
Methods: Samples were taken from the student population of the Faculty of Economics, Universitas Sarjanawiyata Tamansiswa (UST) as many as 148 samples. Meanwhile, to get the data we used a questionnaire distributed online. Furthermore, Structural Equation Modeling (SEM) was used to analyze the proposed hypothesis.
Results: Social Capital and Perception of Information Disclosure positively affect Self-Awareness. Self-Awareness has a positive effect on the Health Protocol Discipline. Meanwhile, Social Capital and Perception of Information Disclosure do not directly affect the Health Protocol Discipline.
Level of Readiness: In particular, research results become strategic inputs related to government policies to create protocol discipline, especially among students. Meanwhile, in general, our research tries to provide a research model in the form of the Empirical Research Model (ERM), which is a strategic mindset in finding the right policy footing, in critical situations
The Role of Motivation and Work Discipline in Improving Employee Performance at the Cikande District Office, Serang Regency
Authors: Saleh Muhammad , Hidayat Ardi
Published: August 2024

This study aims to determine the effect of motivation and work discipline on employee performance at the Cikande District Office, Serang Regency. The population and sample of this study were employees at the Cikande sub-district office totaling 31 people. Data Collection Techniques Used In This Research In The Form Of Questionnaire Consisting Of Five Choices With Likert Scale, Documentation Study And Interview (Interview). While the data analysis technique in this study uses the classical assumption test, multiple linear regression, t test, F test, and the coefficient of determination. The results of the study show that the variables of motivation and work discipline have a positive and significant effect on employee performance at the Cikande District Office, Serang Regency. Based on the partial test, it is known that motivation has a positive and significant effect on employee performance, while work discipline has no effect and is not significant on employee performance
The Role of Physical Activities in Enhancing Physical Fitness Among the Community
Authors: Saefullah Rifki , Hidayana Rizki Apriva , Cahyandari Rini
Published: August 2024

This paper delves into the significance of engaging in sports and physical activities to improve the physical fitness of the community. The study explores the impact of physical activities on overall health and presents various strategies to promote and encourage participation in sports and exercise. The research methodology includes a comprehensive review of literature and case studies to highlight the benefits and challenges of implementing physical activities in enhancing the well-being of society. The findings emphasize the importance of early education, accessible facilities, and technological advancements in fostering a healthier and more active lifestyle. In conclusion, promoting physical activities emerges as a pivotal solution to counter the prevailing sedentary lifestyle and boost the physical fitness of the community.
Creative Innovation: Modernizing the Traditional Game Teng-Teng
Authors: Suhaimi Nurnisaa , Amal Moh Alfi , Azis Chusnul Chatimah
Published: August 2024

Amid the rapid advancement of technology, today’s younger generation increasingly spends their time on smartphones and video games as sources of entertainment and recreation. Unfortunately, many modern games lack the physical interaction and direct communication that are the hallmarks of traditional games. One traditional game that remains known to this day is Ketingting. This game is not only enjoyable but also beneficial for the mental and physical development of its players. Therefore, an innovative adaptation called Ketingting Think has been developed to make this game more unique and creative. With its appealing design and vibrant colors, Ketingting Think is expected to attract the interest of today’s youth. Based on preliminary research conducted in Malaysia, 25% of respondents agreed that this innovation is appealing. Additionally, 35% of respondents felt that this game requires strategy and creativity due to its unique gameplay. Furthermore, 40% of respondents stated that when played in groups, this game can foster teamwork and communication skills, as each team member must communicate and collaborate to win. This innovation aims not only to modernize a traditional game in Malaysia but also to introduce it to Indonesia, so that this cultural heritage can be appreciated by a wider audience.
The Effect of Stevia Leaves as a Sugar Substitute in Reducing the Risk of Kidney Failure: A Literature Study
Authors: Andrian Ibrahim Riza , Lianingsih Nestia , Cahyandari Rini
Published: August 2024

Excessive sugar consumption has been linked to an increased risk of kidney failure, prompting research into alternative sweeteners. This literature study investigates the potential of Stevia leaves (Stevia rebaudiana) as a sugar substitute in reducing the risk of kidney failure. A comprehensive review of studies published between 2013 and 2023 was conducted using databases such as PubMed, ScienceDirect, and Google Scholar. The analysis revealed that high sugar intake, particularly from sweetened beverages, is associated with a higher risk of chronic kidney disease (CKD). Stevia, a zero-calorie sweetener, demonstrated promising results in weight management and glycemic control, both crucial factors in kidney health. Several studies reported improvements in kidney function markers, including serum creatinine and microalbumin levels, in CKD patients supplemented with Stevia. Additionally, Stevia's antioxidant properties may protect kidney tissues from oxidative stress. While the findings suggest Stevia's potential as a beneficial sugar substitute for kidney health, limitations in current research, including short study durations and unclear mechanisms of action, highlight the need for more comprehensive, long-term studies. This review concludes that Stevia shows promise as a tool in the prevention and management of kidney diseases, but further research is needed to fully understand its role and optimize its use in dietary interventions for kidney health.
PROSTHETIC JOINT INFECTION
Authors: Usman Muhammad Andry
Published: August 2024

The number of cases handled by PJI is projected to rise in the coming years. The diagnosis of PJI relies on evaluating microbiology, inflammatory response, and pathology. However, the accuracy of the diagnosis is compromised by previous exposure to antimicrobial agents, the possibility of contamination, and the lack of specificity of inflammatory markers. Although new testing methods, such as molecular techniques, hold the potential for a swift diagnosis, they are constrained by the risk of contamination and the absence of susceptibility results. Interestingly, emerging synovial fluid markers exhibit promise as an additional tool in diagnosing PJI. The management of each PJI case, both in terms of surgery and antimicrobial treatment, requires an individualized assessment. It is imperative to conduct high-quality studies that aim to determine the most effective route and duration of antimicrobial treatment for each surgical approach.  This review provides an overview of the diagnostic tests and treatment options for prosthetic joint infection, offering a practical approach to managing this complex clinical condition.
Infracciones de conducción: la contribución conjunta de la personalidad, la ira y la pasión
Authors: Cardoso Carla , Castro Josefina , Machado Mariana , Da Agra Cândido
Published: August 2024

Este estudio tiene como objetivo explorar la contribución conjunta de la personalidad, la ira al conducir y la pasión en la predicción de las infracciones de tráfico. Además, se caracterizó un perfil de conductores más propensos a cometer infracciones de tráfico. Para lograr estos objetivos, 569 conductores completaron un cuestionario de autoinforme. Se encontró que el psicoticismo, la impulsividad, la búsqueda de sensaciones, la ira al conducir y la pasión obsesiva predecían las infracciones de tráfico. Además, los resultados demostraron que la ira al conducir y la impulsividad mediaban el efecto del neuroticismo en las infracciones de tráfico. Finalmente, se observó que los conductores con más infracciones de tráfico eran hombres, más jóvenes, tenían menos experiencia al volante, habían tenido más accidentes de tráfico y eran responsables de más de ellos.
(A)Quilombar é viver
Authors: De Matos Suelen Karini Almeida
Published: August 2024

Resenha do livro:
NASCIMENTO. Abdias. O Quilombismo: documentos de uma militância pan-africanista. Editora Perspectiva. Rio de Janeiro. 2019.
DESIGN OF A NICKEL BASED MIXED-LIGAND COORDINATION COMPOUND FOR REMOVAL OF CONGO RED DYE FROM WATER
Authors: Adimula V. O. , Aminata S. , Adeniyi E. O. , Obafemi A. D. , Elaigwu S. E. , Owalude S. O. , Tella A. C.
Published: August 2024

Adsorptive uptake of congo red (CR) dye from water by a Ni(II) coordination compound containing carboxylate and N-donor ligands, formulated as [Ni(TDPH)(BPY)] 1, is herein reported (4,4-bipyridine= BPY; 3,3-thiodipropionate= TDPH). Characterization of the compound was done by Scanning Electron microscopy (SEM), Thermogravimetric analysis (TGA), Infrared spectroscopy (FTIR), and X-ray diffraction (XRD) analysis. Experimental data were subjected to isotherm and kinetics studies, an R2 value of 0.9953 was obtained for the Langmuir isotherm while the pseudo-second-order model was observed to be best fit for the experimental data with a correlation coefficient value of 0.9918.
PENGARUH PENERAPAN SISTEM E-FILING, SOSIALISASI PERPAJAKAN, DAN TINGKAT KEPERCAYAAN PADA PEMERINTAH TERHADAP KEPATUHAN WAJIB PAJAK ORANG PRIBADI DI KPP PRATAMA JAKARTA SETIABUDI DUA
Authors: Atito Muhammad , Masripah Masripah
Published: August 2024

This study aims to determine whether there is influence from the implementation of the e-filing system, tax socialization, and the level of trust in the government on individual taxpayer compliance at KPP Pratama Jakarta Setiabudi Dua. The research employs a quantitative approach, focusing on individual taxpayers registered and actively engaged with KPP Pratama Jakarta Setiabudi Dua. Employing probability sampling, 150 respondents constitute the sample. The gathered data undergoes analysis via the SEM-PLS method.The results of this study indicate that the implementation of the e-filing system and the level of trust in the government have a positive effect on individual taxpayer compliance at KPP Pratama Jakarta Setiabudi Dua. Meanwhile, tax socialization has no effect on individual taxpayer compliance at KPP Pratama Jakarta Setiabudi Dua.
Wetenschapsmethodologie in perspectief
Authors: Akkermans Jitte , Van Esbroeck Dieter
Published: August 2024

Onderzoeksbevindingen uit de humane wetenschappen worden te pas en te onpas ingeroepen in het publieke debat. Dit boek verduidelijkt de methoden waarmee die wetenschappers tot hun conclusies komen. Dat helpt hun onderzoek beter naar waarde te schatten. Het boek legt voor verschillende wetenschapsdisciplines uit wat deze bestuderen, hoe ze te werk gaan en wat de verdiensten en beperkingen van hun werkwijze zijn. Het bevat hoofdstukken over zowel literatuurstudies (geschiedenis, theologie, rechten en filosofie) als empirische studies (kwalitatief onderzoek, kwantitatief onderzoek, psychologie en economie), evenals inleidende hoofdstukken over multidisciplinariteit en positivisme. De hoofdstukken kunnen afzonderlijk gelezen worden en veronderstellen geen voorkennis van de verschillende wetenschapsdisciplines. “De samenstellers en auteurs van deze bundel hebben de bewonderenswaardige én uitdagende ambitie om, aan de ene kant, de wetenschappen die aan bod komen in hun eigenheid te laten en, aan de andere kant, hun verwantschappen, gelijkenissen en verschillen duidelijk te maken.” Voorwoord Jean Paul Van Bendegem
Aplikasi Penyembunyian Pesan Pada File-File Dokumen Berekstenti .Xls/Xlsx Dengan Metode Modulus Function
Authors: Zai Indarmawati
Published: August 2024

Securing messages is a very important thing, because it avoids theft of important files from unauthorized parties. Steganography is a way of hiding messages or inserting messages into other media, so that other people do not know the authenticity of the information.
A method is needed so that the data is not lost or is intact until it reaches its destination. In terms of data storage, security is needed so that the stored data cannot be opened, read or even taken by someone who does not have the right to try to open it. To be able to hide messages but not change the container that contains them, a steganography method is needed that can do this. The Modulus Function (MF) method is a message insertion technique that is carried out by modifying the residual value of the quotient (remainder). This method uses quantization of the gray value difference to determine the number of bits to be inserted at a certain value difference. The advantage of this modulus function method is that it is able to reduce changes in coefficient values ​​(coefficient adjustment) so that it is able to maintain the quality of the storage container. So it is in the testing stage with Binary viewer software. Can help in hiding messages in document files
Pengembangan Media Informasi SMK Negeri 1 Plampang Berbasis Android
Authors: Widiya Lis Susana  , Shinta Esabella  , Atmawan Oktavia Siska
Published: August 2024

In the era of globalization and rapid technological development, schools as educational institutions must be able to adapt to these changes. One way to facilitate access to information about schools is by building a school Website that can be accessed by students, teachers, parents, and the general public. SMK Negeri 1 Plampang is one of the vocational high schools in Indonesia located in Sumbawa Regency, West Nusa Tenggara. The school has various programs such as Electrical Engineering, Welding Engineering, Ruminant Livestock Agribusiness, and others. As a school committed to providing the best education for its students, SMK Negeri 1 Plampang has built a school Website as one of the media to provide information about school activities, school profile, class schedules, student achievements, and others. However, school Websites that can only be accessed through a browser on a computer or laptop are sometimes less effective in providing access to information for students, teachers, and parents. Sometimes students or parents do not have access to a computer or laptop when needed, so the necessary information cannot be easily obtained. Therefore, the development of SMK Negeri 1 Plampang's Website into an android-based platform is a solution that is right to facilitate access to information for students, teachers, and parents. By developing SMK Negeri 1 Plampang's Website into an android-based platform, students, teachers, and parents can easily access school information through their smartphones. This android-based application will provide easy access to information, such as class schedules, assignments and exams, school profile, student achievements, and others. In addition, application users can obtain notifications about the latest information from the school, so they will not miss important information. In order to improve the effectiveness and efficiency of school information services, the development of SMK Negeri 1 Plampang's Website into an android-based platform is an appropriate alternative. With the android-based application, it is hoped that students, teachers, and parents can more easily obtain information about school activities, as well as have a better learning experience.
Deep brain stimulation in Parkinson’s disease: Looking back, looking forward
Authors: Lim Erle CH , Quek Amy ML , Seet Raymond CS
Published: August 2024

Patients with Parkinson’s disease (PD) may present with prodromal (e.g. hyposmia, sleep disorders, constipation), motor (e.g. tremors, rigidity, bradykinesia, postural dysfunction) and non-motor (e.g. cognitive dysfunction, depression) symptoms.1 Treatment is symptomatic, targeting motor and non-motor manifestations, but there is presently no effective disease modifying treatment.1 Although PD therapies have primarily been focused on supplementing dopamine, which has improved survival and quality of life of PD patients,1-3 other neurotransmitter systems (e.g. serotonergic, cholinergic and noradrenergic) are also dysfunctional, especially for the non-motor symptoms.1,4,5 By the time patients reach the later stages of PD, many of them would have developed significant gait and balance difficulties, dysarthria, dysphagia and motor fluctuations like wearing off and levodopa-induced dyskinesias (LID), as well as non-motor symptoms such as orthostasis, depression, dementia and psychosis.1,2,6,7
Repetitive transcranial magnetic stimulation for major depression and obsessive-compulsive disorders in Singapore
Authors: Ye Si Jia , Lu LinShan , Tan Xiao Wei , Tor Phern Chern
Published: August 2024

Repetitive transcranial magnetic stimulation (rTMS) is a novel and noninvasive neuromodulation therapy used for treatment-resistant major depressive disorder (MDD)1 and obsessive-compulsive disorder (OCD).2 OCD and depression are disabling psychiatric disorders, which have a detrimental impact on individuals, their families and society.3,4 The lifetime prevalence of depression is high at 5.8% and OCD affects 1 in 28 Singaporeans.5 Depression contributes substantially to the global burden of disease and disability.6 However, despite effective pharmacological and psychological interventions, approximately 40% to 50% of patients have not responded satisfactorily to standard treatment.7
Mengukur Dampak Ekonomi Pengelolaan Wisata Terhadap Perekonomian Masyarakat Desa Molotabu: Studi Empiris dan Rekomendasi
Authors: Solihin Dwi Indah Yuliyani , Wahab Podungge Abdul , Madjid Podungge Abdul
Published: August 2024

This article aims to bridge the existing empirical gap by presenting an in-depth and comprehensive analysis of the management of Molotabu Beach and its impact on the economy of the Molotabu Village community using a holistic, participatory, and innovative approach so that this study is expected to formulate policy recommendations and practical strategies that support the development of sustainable tourism in Bone Bolango Regency.The research method was carried out by analyzing empirical study data, namely: 1) a holistic ecological and environmental approach, namely the health of coastal ecosystems related to biodiversity, water quality, and biodiversity; 2) a participatory approach Community involvement in planning and decision-making, and environmental education and awareness programs for the community. Partnerships and collaborations between government, community and private sector; 3) an innovative approach to the use of environmentally friendly technology in beach management. Innovation in waste management, ecotourism and conservation.The results of the study indicate that: 1) The holistic approach shows that although there has been much progress, there are several shortcomings that need to be fixed. Ecological aspects, including waste management and environmental protection, still face challenges. In addition, awareness and support from the village government in management need to be improved to ensure long-term sustainability and effectiveness; 2) Participatory approach in managing tourism objects in Molotabu Village has shown positive results. Active community involvement in planning and decision-making has strengthened the sense of ownership and responsibility for tourism management; 3) The application of an innovative approach in monitoring and evaluation has shown the potential to improve the management of tourism objects in Molotabu Beach
Conversão termoquímica da biomassa lignocelulósica para produção de bioprodutos
Authors:   , Tuler Grazieli Viana
Published: August 2024

O uso de biomassa como fonte de energia, em substituição aos combustíveis fósseis, é mais sustentável. A biomassa é renovável, de baixo custo e quando produzida de forma adequada pode ter um ciclo de carbono netruo. Esse fator tem impulsionado pesquisas em diversas áreas, como a produção de biocombustíveis e processos de pirólise para produzir bio-óleo. Com isso, é criado alternativas sustentáveis e renováveis aos derivados do petróleo. A pirólise é uma técnica promissora na conversão de biomassa lignocelulósica em produtos líquidos, sólidos e gasosos. O bio-óleo tem despertado crescente interesse devido à sua versatilidade. No entanto, sua alta oxigenação, baixa densidade energética e instabilidade química são algumas das limitações que podem afetar sua eficiência e aplicabilidade. A pirólise catalítica é um método promissor que melhora a qualidade do bio-óleo produzido a partir da biomassa. O objetivo deste trabalho foi avaliar o efeito da pirólise de três biomassas, utilizando quatro temperaturas e dois catalizadores, na produção de bio-óleo. As biomassas utilizadas foram palha de Coffea canephora, conhecido popularmente como Conilon e resíduos de copa e da casca de uma floresta clonal de Eucalyptus grandis x Eucalyptus urophylla. Utilizou-se as temperatutas de 300, 400, 500 e 600ºC e, óxido de cobre (CuO) e dióxido de titânio (TiO2) foram os catalisadores. Com auxilio de um pirolisador acoplado à cromatografia gasosa/massa espectrometria (Py-GC/MS) foram obtidos os rendimentos e a qualidade dos produtos. As biomassas foram caracterizadas quanto a composição química e física. Os principais bio- produtos identificados após a pirólise foram o ácido acético, furfural e levoglucosana, confirmando a importância do processo para obtenção de produtos químicos de alto valor agregado. Na palha de café foram obtidos os melhores rendimentos de ácido acético sem catalisador e furfural com o catalisador óxido de cobre (CuO). Nos resíduos de copa foi obtido o melhor rendimento de levoglucosana com catalisador óxido de cobre (CuO). Nos resíduos de casca não foram obtidas quantidades significativas para produção de compostos químicos. A presença do catalisador de dióxido de titânio (TiO2) não influenciou no rendimento dos resultados. Palavras-chave: Resíduos; Pirólise; Bio-óleo; Química verde.
Via metabólica dos flavonóis em genótipos de soja resistentes ao ataque de insetos pragas
Authors:   , Pinheiro Valquíria Joana Medina
Published: August 2024

O Brasil é o maior produtor mundial de soja e a cultura é uma das contribuintes mais importantes para a economia. As plantações de soja frequentemente sofrem danos causados por pragas de insetos, como a Anticarsia gemmatalis, que também ataca outras culturas. Os genótipos de soja têm sido usados para decifrar os mecanismos de resistência, avaliando a atividade de compostos de defesa como inibidores de proteases (PIs) e flavonóis. No entanto, os determinantes genéticos da resistência ainda não foram investigados minuciosamente. Este estudo utilizou a resposta de genótipos resistentes e suscetíveis de soja para avaliar genes e proteínas responsivos ao ataque de lagartas e envolvidos na biossíntese de flavonóis metilados e glicosilados. Rutina e isorramnetina rutinosídeo foram produzidas constitutivamente nos genótipos resistentes IAC 17 e IAC 100. Após o ataque de insetos, genes que codificam a sintase de flavonóis e metiltransferases foram altamente regulados em IAC 17. Algumas respostas de defesa contra herbivoria parecem ser constitutivas, enquanto outras foram induzidas ou independentes de JA, como verificado nos níveis de flavonóis. Os níveis de ácido salicílico foram mais altos em IAC 17 e IAC 100. Proteínas ainda não caracterizadas por seu envolvimento em interações planta-inseto, como receptores transmembrana e fatores de transcrição, foram reguladas positivamente no genótipo resistente IAC 17. Parece que a biossíntese constitutiva de flavonóis em ambos IAC 17 e IAC 100 foi herdada do genitor PI229358, tornando os dois genótipos boas fontes genéticas para estudar a biossíntese de flavonóis e sua relação com a resistência a insetos. Palavras-chave: Pragas de insetos. Resistência. Análise proteômica. Análise metabolômica.
Chronic cough in a patient with nonerosive reflux disease: a clinical case
Authors:   Smolensk State Medical University, Smolensk, Russia, Dekhnich N.N. , Kovalenko T.N. ,   Smolensk State Medical University, Smolensk, Russia, Shadrina N.E. ,   Smolensk State Medical University, Smolensk, Russia; Clinical hospital No 1, Smolensk, Russia
Published: August 2024

Chronic cough associated with reflux is one of the extraesophageal manifestations of gastroesophageal reflux disease (GERD), and in some cases may be the leading or only manifestation of GERD. This article presents a clinical case of a patient with chronic cough, who, during the examination, was diagnosed with GERD, extraesophageal manifestations, reflux-associated cough. The use of the Reflux Symptom Index (RSI) questionnaire has helped in the diagnosis of laryngopharyngeal reflux. The absence of convincing evidence of GERD according to esophagogastroduodenoscopy was an indication for 24-hour pH impedance measurements, which made it possible to confirm the diagnosis. Lifestyle modification and combination therapy with rabeprazole and rebamipide are an effective approach in the treatment of extraesophageal manifestations of non-erosive reflux disease in the form of reflux-associated cough.
Complicated magnetic foreign objects of the gastrointestinal tract: two clinical cases
Authors:   Feodosian Medical Center, Feodosia, Russia, Shchegolev Dmitrii V. , Chalbash Dilyaver A. ,   Feodosian Medical Center, Feodosia, Russia, Umerov Memet Yu. ,   Feodosian Medical Center, Feodosia, Russia
Published: August 2024

Among the foreign bodies (FB) of the digestive tract, magnets account for approximately 1.97%. The presence of magnetic FB in the gastrointestinal tract is characterized by nonspecific symptoms, difficulties in collecting anamnesis due to the age of patients and low alertness of parents and medical professionals. Currently, multiple magnets are the most dangerous FB of the gastrointestinal tract. Being in different parts of the digestive tract, they are attracted to each other and cause a number of complications: ischemia and bedsores of the wall of the hollow organ, volvulus, intestinal obstruction, perforation of the wall and surrounding anatomical structures, intestinal fistulas, bleeding, intussusception. 2 clinical examples of the presence, developed complications and surgical removal of multiple magnetic FB and postoperative management of patients are described. The peculiarities of the cases are the formation of an interintestinal fistula passing through the mesentery of the small intestine, as a result of the attraction of magnets located in different parts of the small intestine, and the formation of 4 perforations located in different parts of the intestine, as a result of the attraction of 3 magnets. Magnetic FB themselves in the gastrointestinal tract, as a rule, do not have clinical manifestations; symptoms correspond to developed complications. Not all children report ingesting magnetic FB. To exclude magnetic FB left during surgery in the gastrointestinal tract, intraoperative radiography is necessary.
Renal hemodynamic changes and kidney function in the first day after percutaneous nephrolithotripsy
Authors:   Ulyanovsk State University, Ulyanovsk, Russia, Belyi Lev E. , Klochkov Artem V. ,   Ulyanovsk State University, Ulyanovsk, Russia; Ulyanovsk Regional Clinical Center for Specialized types of Medical Care named after Honored Doctor of Russia E.M. Chuchkalov, Ulyanovsk, Russia, Klochkov Vladimir V. ,   Ulyanovsk State University, Ulyanovsk, Russia, Shmyrin Alexander G. ,   Ulyanovsk Regional Clinical Center for Specialized types of Medical Care named after Honored Doctor of Russia E.M. Chuchkalov, Ulyanovsk, Russia
Published: August 2024

Background. Over the past decade, percutaneous nephrolithotripsy (PNL) has become one of the most popular treatments for urolithiasis. The reason is the high efficiency of the method in combination with a low incidence of complications and a shorter period of hospitalization. However, the effect of PNL on renal function has not been sufficiently studied. The aim of this study was to evaluate changes in renal hemodynamics and kidney function in the early postoperative period after PNL. Patients and Methods. The clinical data of 18 patients who underwent PNL were analyzed. Serum creatinine levels were determined in all patients before and after PNL, glomerular filtration rate was calculated, and ultrasound examination of the kidneys with dopplerography of renal blood flow was performed. The size, density of the stone and its localization in the kidney were determined using computed tomography. Results. The average size of the stones was 224.4±38.5 mm2, the average density was 1152±76 HU. The duration of surgical intervention is 96.1±9.2 minutes. In 7 patients after PNL, creatinine levels decreased compared to preoperative, while in the remaining 11 patients, creatinine levels increased in the early postoperative period (p<0.001). Acute kidney injury developed in three patients (16.7%): there was an increase in creatinine concentration by 40.7±11.7 mcmol/l compared with the baseline level. In patients with both improved renal function on the first day after surgery and with deterioration of function, the same type of changes were revealed. There was an increase in vascular resistivity. This does not allow the use of dopplerography of renal blood flow as prognostic predictors of impaired renal function. Unlike the duration of the intervention, the size of the stone remains the main predictor of the risk of acute kidney injury after PNL.
Clinical observation of a complete clinical, radiological and pathomorphological response in a patient with locally advanced gastric adenocarcinoma after neoadjuvant therapy
Authors:   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia, Mironova Diana Yu. , Skoropad Vitaliy Yu. ,   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia, Silanteva Natalya K. ,   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia, Agababyan Tatev A. ,   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia, Zhavoronkova Ekaterina S. ,   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia, Ivanov Sergey A. ,   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia; Patrice Lumumba People’s Friendship University of Russia (RUDN University), Moscow, Russia, Kaprin Andrey D. ,   National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow, Russia; Patrice Lumumba People’s Friendship University of Russia (RUDN University), Moscow, Russia;
Published: August 2024

Stomach cancer is an aggressive disease and represents a global health problem. Currently, more than 50% of patients with a newly diagnosed stomach cancer have a locally advanced process that requires a combined approach – a combination of surgical treatment and neoadjuvant/perioperative therapy. In a number of patients, after neoadjuvant therapy, there is a marked or even complete regression of the tumor; the prognosis of the disease, as well as the need for adjuvant therapy in this category of patients is the subject of discussion. This paper demonstrates the clinical observation of a complete clinical, radiological and morphological response after neoadjuvant therapy (2 cycles of chemotherapy FLOT + chemoradiotherapy), as well as long-term relapse-free survival in a patient with locally advanced gastric cancer.
Borderline ovarian tumors in women of childbearing age: diagnosis, treatment
Authors:   Patrice Lumumba Peoples' Friendship University of Russia, Moscow, Russia, Orazov Mekan R. , Kiseleva Marina V. ,   Tsyb Medical Radiological Research Centre – branch of the National Medical Research Center of Radiology, Obninsk, Russia, Pernay Vladlena M. ,   Patrice Lumumba Peoples' Friendship University of Russia, Moscow, Russia
Published: August 2024

Borderline ovarian tumors were first infected about 100 years ago. They are detected at an early stage and have a favorable outcome. But, as is known, relapse can begin within 20 years after therapy. Most often they occur in young women who are still interested in reproductive function, which influences the choice of further treatment tactics. Borderline ovarian tumors can indeed be challenging to diagnose based solely on clinical and ultrasound data. Accurate diagnosis often requires surgical intervention and histological examination of the tissue obtained. The review you mentioned likely covers various methods of diagnosis and treatment for borderline ovarian tumors, given the complexity of their diagnosis and management. Many discussions on this topic often address the challenges of accurate diagnosis and available treatment options.
Analysis of techno-dependence in Peruvian university students
Authors: Miauri Aza Dery Saida , Alfaro Zuniga Eleana Fernandina , Najar Soto Marcela Milagros
Published: August 2024

Techno-dependence is the repetitive and compulsive habit about the use of technological resources, over and above their normal use for daily life. This dependence compromises the health and social life of individuals, affecting their general well-being. The purpose of the study was to analyze this habit in university students and compare the results with demographic variables. A cross-sectional and retrospective design with a quantitative approach was used. 450 university students participated, intentionally selected. The results showed a high techno-dependence (84.7%) and high scores in aspects such as life on social networks, mute generation, compulsive cell phone use and phubbing. This confirms the presence of a technological dependence that affects academic performance and other life activities.
Composition of Bioactive Compounds from Potato Peel Waste Extracts by Decoction and Indirect Ultra-Sound Assisted Extraction Methods
Authors: Hagenimana Theoneste , Anyango Joseph Ochieng , Muliro Patrick Simiyu , Bitwayiki Clement
Published: August 2024

Purpose: The aim of this study was to obtain potato peel extracts by a conventional, “decoction (DT)” and novel, “indirect ultra-sound assisted extraction (DuAE)” methods, and determine the composition of potato peel extracts in bioactive compounds.
Materials and Methods: To obtain peels extracts, both DT and DuAE extraction methods were used to extract bioactive compounds from peel wastes of five potato cultivars i.e. Kinigi, Kuruseke, Kirundo, Peco, and T58, locally grown in Rwanda. Four types of bioactive compounds, i.e. glycolakaloids (TGC), total phenolics (TPC), total flavonoids (TFC), and total anthocyanins (TAC) were determined in each potato peel extract. Data in concentration of bioactive compounds was subjected to a two factor ANOVA (p ≤ 0.05) to determine the effect of potato cultivars and extraction methods on the content of bioactive compounds.
Findings: Results showed that the composition ranges of bioactive compounds were 0.47- 11.83 mg SE/100g, 60.12 -1170.01 mg GAE/100g, 50.39- 873.26 mg QE/100g, and 0.71- 8.73 mg CGE/100 g per dry weight for TGC, TPC, TFC, and TAC, respectively. The composition of bioactive compounds in potato peel extracts was significantly (p<0.001) affected by both potato cultivar and extraction method. Generally, potato peel extracts from Kirundo and Kuruseke cultivars had the lowest and the highest amount of bioactive compounds, respectively; whereas the DuAE method performed better than DT method.
Implications to Theory, Practice and Policy: Results from this study revealed the significant role of extraction methods used for bioactive compounds. An investigation on the optimization and improvement of extraction processes used in this study was recommended.
Bioabsorption of Maize Cob and its Derivative in the Elimination of Heavy Metals from Waste Water in Some Local Government Areas of Kaduna State, Nigeria
Authors: DIKWA Karderam Bukar UCHE Ikechukwu , HARUNA Ali Ahmed VICTORIA Moltong Yilwa , Okpaga UME Austine
Published: August 2024

Industrial waste water is a significant cause of water pollution. Many health challenges can be linked to high intake of heavy metals directly or indirectly into the body system beyond which is required to function adequately. This study evaluated the bioabsorption potentials of Maize Cob (MC), Maize Cob Charcoal (MCC), and Ethylenediamine-disuccinate treated Maize Cob (ETMC) in the elimination of heavy metals from industrial waste water in Kaduna South and Chikun Local Government Areas. Industrial waste water samples were collected from Defence Industries Corporation of Nigeria (DICON), Bam Paint Industry (BAM-PAINT), Chellco Industry (CHELLCO) and Nigerian Breweries plc (NBC). Heavy metals were analyzed using Atomic Absorption Spectrophotometry (AAS). MC, MCC and ETMC were used to treat the industrial waste water through Batch sorption experiment at 0.42mm particle size. Zinc (Zn2+), Copper (Cu2+), Cadmium (Cd2+), Nickel (Ni2+) and Lead (Pb2+) were the detected at different concentrations across the samples. The results showed that concentration of Zn2+ ion present in the study areas ranged from 0.442 ± 0.005 to 3.943 ± 0.031mg/g. Cu2+ ion ranged from 0.226 ± 0.003 to 9.730 ± 0.001 mg/g, Cd2+ (-0.040± 0.005 to 0.624 ± 0.003 mg/g), Ni2+ (0.184 ± 0.004 to 12.096 ± 0.003 mg/g) and Pb2+ (-0.142± 0.003 to 1.128 ± 0.002 mg/g). Heavy metal absorption efficiencies by MC differ significantly (p < 0.05). MC had the highest adsorption rate (92%) for Zn2+ ion in DICON Company waste water. Cu2+ was reduced by 40% in waste water from BAM-PAINT Company, 94% for Cd2+ ion in NBC waste water, 72% for Ni2+ and 98% of Pb2+ in NBC waste water. Heavy metal removal efficiency after using MCC showed significant difference (p < 0.05) in the heavy metals adsorption rate. There was 85% reduction in the concentration of Zn2+ and 40% of Ni2+ in industrial waste water from DICON Company. The absorbent was most effective in reducing the concentration of Cu2+ ion present in NBC by 187% and 154% of Cd2+ ion in sample from BAM-PAINT Company, while, Ni2+ and Pb2+ had reduction rate of 60% and 95% at DICON and NBC respectively. ETMC drastically reduced the concentration of Zn2+ ions from to -604.533 ± 2.512 mg/g in CHELLCO industry and Cu2+ions to -9.567 ± 0.351 mg/g in BAM-PAINT waste water. Therefore, it can be concluded that Maize Cob, Maize Cob Charcoal and Ethylene diamine disuccinic treated maize cob are effective absorbent for eliminating lead, zinc, cadmium, nickel and copper from waste water.
An Investigation of Primary School-Based Governance in a Decentralised Education System
Authors: Chitanda Mercy , Nyirongo Richard , Semphere Nertha Kate
Published: August 2024

Countries that adopt decentralisation policy expect that implementation of the policy will lead to achievement of the policy objectives. Malawi adopted the policy with the aim of promoting good governance which entails transparency, accountability and participation among other objectives. This article presents findings of the study that aimed to assess primary schools-based governance in primary schools in Lilongwe district. The study took the form of mixed methods approach in which both qualitative and quantitative methods were employed. The respondents included primary school stakeholders who were sampled purposively. Data from the two methods were collected and analysed sequentially and the findings were integrated during interpretation phase. Results revealed that there were indicators of good governance in both primary schools. All stakeholders were involved in decision making and actively participated in school-related activities. However, learners were usually involved in the implementation phase only due to the long-standing belief that children cannot speak for themselves. Despite low learners’ involvement in decision making, the results provided evidence to conclude that transferring powers from the central government to the local governments promotes good governance.