bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of different predominant lesions in intracranial bifocal germ cell tumors to predict neuroendocrine outcomes
Authors: Liang Dan , Chen Han , Zhong Li-Yong
Published: June 2023

Purpose

Intracranial germ cell tumors frequently arise from the midline of the brain, occasionally presenting as bifocal diseases. The predominant lesion might affect clinical characteristics and neuroendocrine outcomes.

Method

A retrospective cohort study involving 38 patients with intracranial bifocal germ cell tumors was performed.

Result

Twenty-one patients were assigned to the sellar-predominant group, while the other 17 patients were assigned to the non-sellar-predominant group. Differences in gender ratio, age, manifestation, the incidence of metastasis, the incidence of elevated tumor markers, human chorionic gonadotropin levels in serum and in cerebrospinal fluid, diagnostic method, and tumor type were not significant between the sellar-predominant group and the non-sellar-predominant group. Before treatment, the sellar-predominant group had a higher incidence of adenohypophysis hormone deficiencies and central diabetes insipidus than those of the non-sellar-predominant group, without significant differences. After multidisciplinary therapy, the sellar-predominant group also had a higher incidence of adenohypophysis hormone deficiencies and central diabetes insipidus than those of the non-sellar-predominant group. The differences in the hypothalamic–pituitary–adrenal (HPA) axis impairment (P = 0.008), hypothalamic–pituitary–thyroid (HPT) axis impairment (P = 0.048), and hypothalamic–pituitary–gonad (HPG) axis impairment (P = 0.029) were significant between sellar-predominant group and non-sellar-predominant group, while the others were not. At median 6 (3, 43) months of follow-up visit, sellar-predominant group had a higher incidence of adenohypophysis hormone deficiencies than those of non-sellar-predominant group. The differences in the HPA impairment (P = 0.002), HPT impairment (P = 0.024), and HPG impairment (P < 0.000) were significant, while the others were not. Further comparison of the neuroendocrine function between different subtypes of sellar-predominant patients indicated that the differences in adenohypophysis hormone deficiencies and central diabetes insipidus were not significant between the two subtype groups.

Conclusion

Bifocal patients with different predominant lesions present similar manifestations and neuroendocrine disorders before treatment. Non-sellar-predominant patients would have better neuroendocrine outcomes after tumor treatment. The distinction of the predominant lesion in patients with bifocal intracranial germ cell tumor plays a valuable role in predicting neuroendocrine outcomes, as well as in optimizing long-term neuroendocrine management during survival time.
Walking on water: subchondral vascular physiology explains how joints work and why they become osteoarthritic
Authors: Beverly Michael , Murray David W
Published: June 2023

This review of bone perfusion introduces a new field of joint physiology, important in understanding osteoarthritis.

Intraosseous pressure (IOP) reflects conditions at the needle tip rather than being a constant for the whole bone. Measurements of IOP in vitro and in vivo, with and without proximal vascular occlusion confirm that cancellous bone is perfused at normal physiological pressures.

Alternate proximal vascular occlusion may be used to give a perfusion range or bandwidth at the needle tip more useful than a single IOP measure.

Bone fat is essentially liquid at body temperature. Subchondral tissues are relatively delicate but are micro-flexible. They tolerate huge pressures with loading.

Collectively, the subchondral tissues transmit load mainly by hydraulic pressure to the trabeculae and cortical shaft.

Normal MRI scans demonstrate subchondral vascular marks which are lost in early osteoarthritis.

Histological studies confirm the presence of those marks and possible subcortical choke valves which support hydraulic pressure load transmission.

Osteoarthritis appears to be at least partly a vasculo-mechanical disease. Understanding subchondral vascular physiology will be key to better MRI classification and prevention, control, prognosis and treatment of osteoarthritis and other bone diseases.
Retos en Seguridad y Salud en el Trabajo: enfermos de Síndrome de la Inmunodeficiencia Adquirida (SIDA) y portadores del Virus de Inmunodeficiencia Humana (VIH)
Authors: Acevedo Gómez Angélica Johanna
Published: June 2023

El presente artículo expone la protección especial que se ha brindado a las personas portadoras de VIH y enfermos de SIDA en la normativa vigente y de forma especial en el recorrido a lo largo de los años en la jurisprudencia de la Corte Constitucional, la cual, genera en los responsables del Sistema de Gestión de Seguridad y Salud en el Trabajo bastantes retos a superar para realizar una gestión preventiva adecuada sin vulnerar otros derechos fundamentales de estas personas. Así pues, para el desarrollo de esta temática se encontrarán los siguientes apartados, primero “Diferente tratamiento médico, igual tratamiento laboral” donde se expone someramente lo relacionado con la diferenciación en el tratamiento de una persona infectada con VIH y aquellas que son diagnosticados con SIDA, posteriormente, la “Evolución de la protección de los trabajadores infectados con VIH/Enfermos de SIDA en la jurisprudencia de la Corte Constitucional con su incidencia en la gestión preventiva en Seguridad y Salud en el Trabajo” con el fin de comprender el estado jurisprudencial para el tratamiento de las personas que se encuentren en dichas situación, se prosigue con la “Vigilancia de la salud” como obligación del empleador, aspecto que, da lugar al siguiente apartado “procesos de rehabilitación y reincorporación laboral” para así, finalmente exponer las obligaciones desde el “riesgo psicosocial y prevención del acoso laboral.
Las familias campesinas y los sistemas de producción de leche en el cañón de Anaime (Colombia)
Authors: Martínez Restrepo Gloria Lucía , Mora-Delgado Jairo , Menéndez Gámiz Carlos
Published: June 2023

La caracterización de sistemas de fincas y hogares en la cuenca del río Anaime en el municipio de Cajamarca – Tolima fue el objetivo de este estudio. Se aplicaron 53 encuestas al azar. La encuesta abarcó aspectos humanos, sociales, físicos, financieros y naturales. La tipificación evidenció tres grupos de fincas: el grupo 1 poseía una baja proporción de tierra con una importante actividad económica dedicada los cultivos (51.5%), el grupo 2 con actividad económica equitativa entre componente pecuario y agrícola (50%) y el grupo 3 con una gran cantidad de tierra dedicada a la actividad ganadera (60%). El grupo 2 y 3 al tener pocas hectáreas de tierra tiene poco terreno dedicado a la conservación, por el contrario el grupo 3 tiene una alta significancia en este uso del suelo. La producción láctea genera un importante ingreso monetario a las familias además de servir como producto proteico base de la alimentación de las mismas.
Certain Relevant Issues of Interviewing Minors and Victims in the Practice of Law Enforcement Institutions During Criminal Proceedings
Authors: Pranka Darius
Published: June 2023

Over a decade ago, an audit was conducted in Lithuania to assess the protection of children’s rights during criminal proceedings. The audit identified various shortcomings and issues related to child interviews. These problems were addressed in 2017 with the implementation of amendments to the Law on Criminal Procedure of the Republic of Lithuania, which have been in effect for over five years. This article aims to analyze the current practices, particularly in recent years, of law enforcement institutions when conducting interviews with minor witnesses and victims during criminal proceedings. Through analysis and empirical research, it was found that minors are frequently questioned outside of designated child interview rooms for unjustifiable reasons. Furthermore, their rights, particularly the right not to testify against their relatives or family members, are not always adequately explained to them. The legal significance of such procedural violations is discussed. Additionally, it is highlighted that employees of the Child Rights Protection and Adoption Service often lack proper preparation for conducting interviews with children. The article concludes by summarizing other findings from the empirical research.
Defining Heart Failure Based on Imaging the Heart and Beyond
Authors: Graham Fraser J , Iaconelli Antonio , Sonecki Piotr , Campbell Ross T , Hunter David , Cleland John GF , Pellicori Pierpaolo
Published: June 2023

Water and salt retention, in other words congestion, are fundamental to the pathophysiology of heart failure and are important therapeutic targets. Echocardiography is the key tool with which to assess cardiac structure and function in the initial diagnostic workup of patients with suspected heart failure and is essential for guiding treatment and stratifying risk. Ultrasound can also be used to identify and quantify congestion in the great veins, kidneys and lungs. More advanced imaging methods might further clarify the aetiology of heart failure and its consequences for the heart and periphery, thereby improving the efficiency and quality of care tailored with greater precision to individual patient need.
Fatores associados ao risco de câncer de próstata
Authors: Oliveira Rubia Fonseca Santos , Rosa Randson Souza , Bezerra Cristian Lucas dos Santos , Macedo Darlyane Antunes , Boery Rita Narriman Silva de Oliveira , Bomfim Eliane dos Santos , De Oliveira Bruno Gonçalves , Guimarães Frank Evilácio de Oliveira
Published: June 2023

Objetivo Analisar os fatores associados ao risco de câncer de próstata.
Métodos O estudo consiste em uma revisão integrativa, compreendendo os anos de 2008 a 2018, em artigos que tenham como tema principal o câncer de próstata e os fatores de riscos, realizada no banco de dados do portal da Biblioteca Virtual em Saúde (BVS), e nas bases da Literatura Latino-Americana e do Caribe (LILACS), Banco de Dados em Enfermagem (BDENF).
Resultados Após pré-leitura e leitura seletiva, selecionaram-se 11artigos.
Conclusão A abordagem dos homens na consulta de enfermagem é de fundamental importância na identificação dos fatores de riscos, sinais e sintomas de possíveis alterações, com o objetivo de rastrear e diagnosticar precocemente as neoplasias prostáticas, a fim de reduzir a mortalidade de uma população que historicamente não possui o habito de procurar os serviços de saúde, aumentando assim a incidência de doenças e agravos.
Experiencias en la implementación de servicios para la protección de la lactancia materna en Bogotá
Authors: Ballesteros-Bolívar Edith Villalobos , Camargo Sánchez Andrés , Vargas Rafael
Published: June 2023

Objetivo Explorar la experiencia de profesionales de la salud y su rol en la implementación de servicios para la protección de la lactancia materna dentro del sistema obligatorio de garantía a la calidad en salud (SOGS).
Método Se realizó una investigación fenomenológica cualitativa desde la perspectiva Heideggeriana. La recolección de datos se realizó por medio de entrevistas semiestructuradas individuales a 7 profesionales de la salud. Se les preguntó sobre el rol que han desempeñado en la implementación de la sala amiga de la familia lactante.
Conclusiones El profesional de salud es fundamental para implementar servicios delactancia materna, ya que, según las experiencias compartidas, se evidenció que desempeña labores definidas dentro del proceso administrativo que van desde la planeación hasta el control de los procesos asistenciales, pero, además de esto, el profesional es competente para orientar y educar a las mujeres en los periodos de gestación y lactancia.
Suicides risk and crises suffered in the context of COVID-19, mediated by interpersonal family communication
Authors: Garcés Prettel Miguel , Geney Castro Elías , Gutiérrez Ruiz Karol , SantoyaMontes Yanin
Published: June 2023

Objective To analyze the relationship between suicidal ideation and the concerns or affectations perceived at the family, economic and health levels during the first year of the COVID-19 pandemic in Colombia and the mediating role of family communication. Method Participants were obtained through cluster sampling and quotas, resulting in 660 Colombians (Z=1,96; variance =,25; error =3,9%), who answered a questionnaire consisting of three reliable scales between November 1 and 30, 2020, after providing informed consent. Binary logistic regression was used to evaluate the concerns or affectations that most influenced suicidal ideation during this period. Results Thirty-five percent of the Colombian participants presented a high level of suicidal ideation. The concerns or affectations that most strongly explain this level come from the realm of health and intrafamily relationships. The effect of health concerns or affectations on suicidal ideation decreases by up to 32,4% when family communication is open. Likewise, when this type of positive communication is present, the effect of the concerns or affectations perceived in the family, such as breakdowns, distancing and crisis of coexistence, on suicidal ideation decrease between 29,1 and 70,1%. Conclusion Open family communication is a protective factor for mental health in crisis contexts because it can contribute to preventing suicide and alleviate to the concerns or affectations generated by COVID-19. Therefore, it is necessary to strengthen mental health programs through a communicative approach aimed at promoting assertive family dialog to achieve greater attention and openness to talk about concerns and affectations suffered.
La religión del aborto terapéutico en Costa Rica
Authors: Rodríguez Sequeira Claudia
Published: June 2023

Actualmente, América Latina se encuentra sumida en un alto nivel de polarización, entre visiones progresistas y conservadoras, Costa Rica no ha sido la excepción. Esto resulta en que en el debate por el aborto terapéutico han primado los argumentos religiosos sobre los argumentos técnicos, permeando así el campo de acción del Derecho: desde la creación de la norma hasta la aplicación de ésta y sus consecuencias. Es necesario reflexionar sobre la posición del Derecho en los conflictos sociales, evidenciando así los factores políticos, religiosos e ideológicos que convergen y que, sobre todo, se esconden en él. El aborto terapéutico encuentra dificultades para su aplicación y así como existen esfuerzos por reducir su ámbito de acción, hay esfuerzos por regular ese ámbito, pero se deben tomar en cuenta sus implicaciones bioéticas.

Palabras claves: Aborto terapéutico, bioética, religión, política criminal
Límites y Alcances del Concepto de Corrupción de conformidad con las Convenciones Internacionales.
Authors: Arroyo Guitiérrez José Manuel
Published: June 2023

Llamar las cosas por su nombre  en el lenguaje ordinario y cotidiano es de gran importancia para una buena comunicación entre las personas. Conservar este principio cuando se desarrolla un tema especializado, por ejemplo en el ámbito técnico-jurídico, resulta esencial no sólo por la obligada claridad que debe imponerse en la transmisión de conocimientos, sino por la imperiosa necesidad de fijar los límites conceptuales dentro de los cuales se desarrolla esa transmisión, a partir de los presupuestos que cualquier argumentación debe cimentar a la hora de un intercambio o debate teórico-práctico.
La Odisea de la Doble Conformidad en Costa Rica.
Authors: Harbottle Quirós Frank
Published: June 2023

En el presente artículo, en un primer apartado, se expone sobre el origen y la conceptualización de la doble conformidad en el proceso penal costarricense. Se parte de la premisa de que las resoluciones N° 2014-013820 y N° 2014-17411 de la Sala Constitucional y los posteriores fallos que emitió dicho Tribunal, incluso hasta fecha reciente, contribuyeron a la disparidad de criterios jurisprudenciales en Costa Rica en relación con la aplicación del     artículo 466 bis del Código Procesal Penal. Ello queda en evidencia al haberse estudiado múltiples resoluciones de los Tribunales de Apelación de Sentencia Penal y de la Sala de Casación Penal de la Corte Suprema de Justicia en el período 2014-2020. Por último, partiendo del modelo actual de impugnación en el proceso penal, y debido a la gran cantidad de posiciones en la jurisprudencia, se plantean una serie de interrogantes -a modo de una guía orientadora- con el objetivo de que este tema pueda visualizarse con mayor claridad con miras a reformas legislativas que generen mayor seguridad jurídica.
El efecto “Sísifo” de fallidas reformas judiciales en CR: Bases para la transformación de una justicia penal lenta y burocrática
Authors: Chinchilla Calderón Rosaura
Published: June 2023

Con este texto me propongo mostrar el fracaso de las últimas reformas procesales en Costa Rica (en las que, obviamente, no intervino don Daniel) en virtud de las cuales se crearon los tribunales de flagrancia y la apelación de sentencia penal y señalar una posible ruta (sujeta a discusión) sobre los cambios que son necesarios para retomar la senda de una justicia pronta, pero con respeto a las garantías de todas las personas.

No obstante, antes es preciso efectuar una breve reseña de la evolución que ha tenido el sistema penal costarricense para, ubicados en tal contexto, tener una mejor perspectiva de lo que significaron aquellas variaciones.
LA CONSTRUCCIÓN DE LA POLÍTICA CRIMINAL MEDIÁTICA COSTARRICENSE POR MEDIO DEL DIARIO EXTRA
Authors: Trejos Robert Sergio
Published: June 2023

Estudiar el tratamiento del fenómeno delictual por parte de los medios de comunicación de masas es uno de los nuevos desafíos de la criminología. Estas empresas con fin de lucro transmiten una imagen distorsionada de la criminalidad y del sistema penal. Por medio del estudio de todos los títulos de la portada del Diario Extra publicados durante el año 2017 se estudiará -empíricamente- la imagen del delito que transmite ese medio de comunicación de masas.
¿SE CUMPLE EN COSTA RICA EL DERECHO HUMANO A LA DURACIÓN RAZONABLE DEL PLAZO EN EL PROCESO PENAL?
Authors: Polanco Méndez Natalia
Published: June 2023

Después de haber interpuesto un proceso penal, ¿cuánto tiempo tiene que pasar para que pueda alegarse que se está afectando el derecho de acceso a la justicia? Una excesiva duración del proceso penal conlleva implicaciones para todas las partes del proceso, en relación con el acceso a la justicia; la extinción o lesión de las situaciones jurídicas invocadas, debido al paso del tiempo; afectación al principio de libertad, a la presunción de inocencia y aquellos casos específicos relacionados con la prisión preventiva, en los cuales se dicte esta medida cautelar; y para la sociedad en general conlleva implicaciones tanto económicas como políticas, las cuales este artículo científico tiene por objeto analizar.
“MÁS ALLÁ DE MI LIBERTAD PARA DECIDIR… NO FUI YO, FUERON MIS CIRCUNSTANCIAS” ¿QUÉ HAY EN EL CEREBRO DE UN PSICÓPATA Y UN SUJETO VIOLENTO?
Authors: Argüello Quesada Carmen
Published: June 2023

La presente investigación, plantea una reflexión crítica que pretende despertar en el lector, una nueva noción de la culpabilidad a partir de la neurociencia y sus aportes a la ciencia jurídica. Se somete a un análisis, el abordaje jurídico internacional, el criterio de libre albedrío, sus alcances y las tendencias en otros países, que han ratificado sentencias en torno a la evidencia científica y la extensión de su uso en la jurisprudencia del derecho comparado. Seguidamente, se analiza el cerebro de los psicópatas y personas violentas, para intentar presentar los ejes transversales, en torno a las anomalías de estos sujetos y con ellas, los alcances de la neurociencia y cómo este saber representa un punto de inflexión que propicia un debate, sobre una nueva forma de reproche, con una mirada más humana y comprensiva del entorno de los imputados. Se desarrolló una metodología cualitativa, para mostrar casos que han presentado evidencias acerca de la condición de psicopatía y violencia en casos penales, para fundamentar el criterio de culpabilidad. El análisis de la información sustentada en el diagnóstico médico, ha repercutido en el veredicto judicial, en cuanto a la responsabilidad legal y su uso para futuros planteamientos en el derecho local. Analizamos la explicación biológica de la psicopatía y la violencia en comparación con la evidencia neurológica. El dilema entre la culpabilidad, el libre albedrío y el conocimiento novedoso de la neurociencia, proponen la posibilidad de reducir el plazo de la sentencia o el efecto de mitigación, con base en la evidencia de la neurociencia.
Efficiency enhancing of the local capture hood due to air barriers
Authors: Voznyak Orest , Kaplun Victor , Spodyniuk Nadiia , Dudkiewicz Edyta , Dovbush Oleksandr , Sukholova Iryna , Kasynets Mariana
Published: June 2023

This article is related to investigations of the capture hoods of the local exhaust ventilation. The purpose of the research: to increase the zone of action of local exhaust hoods and reduce the amount of air removed. It is equipped with two barriers for air: ring and cylindrical. The empirical dependences for air velocity determination near the suction zone are obtained. Graphs, chart and three-dimensional image visualizations of removed air jet velocity near capture hood with barriers for air are designed. The reduction of production energy consumption, material, and ventilation system maintenance costs due to the correction of the design of the capture hood are the main benefits of the new solution.
NVSR 72-8: Fetal Mortality: United States, 2021
Authors: Gregory Elizabeth , Valenzuela Claudia , Hoyert Donna
Published: June 2023

This report presents 2021 fetal mortality data by maternal race and Hispanic origin, age, tobacco use during pregnancy, and state of residence, as well as by plurality, sex, gestational age, birthweight, and selected causes of death.
ENERGY EFFICIENCY POLICY IN CIVIL ENGINEERING: OPPORTUNITIES AND PROSPECTS FOR APPLICATION
Authors: ARUTIUNIAN I. A. , ZHAMILOV O. D. , VEREMIY H. E.
Published: June 2023

Objective. To analyze the problems of implementation of modern energy efficient systems in Ukraine. The advantages of modern technologies over outdated ones are presented. The results of the study should form the basis for the development of recommendations for improving energy efficiency in civil engineering. Problems. Today in Ukraine, solving the problem of energy saving in civil engineering remains a constant priority. Overcoming this obstacle largely determines Ukraine’s recovery from the economic crisis. According to estimates, energy consumption for heating budgetary institutions in Ukraine is 2 … 3 times higher than in the EU countries for the same needs. This is based on the obsolescence of Ukraine’s building stock from the time of intensive construction in the 1960s and 1980s. Analysis. Many countries are already successfully implementing new technologies, materials, and designs that help improve the energy efficiency of buildings. Examples include: a construction concept based on the idea of creating a building that does not require active heating and cooling – a «passive house», the use of SIP panels made from recycled materials, the use of double-glazed windows with «warm edge» technology, the creation of energy-efficient envelope structures such as the construction projects «The Edge», «ZEB Pilot House», «BedZed». Scientific novelty. Analysis of current problems of energy efficiency policy implementation in Ukraine in terms of various aspects, such as legal, economic, technical, social, etc. Cases of successful implementation of energy efficient measures and technologies in civil engineering in European countries are considered. Practical significance. The analysis of the real energy status of the country’s building stock is the basis for the development and support of energy efficiency policy. The considered cases of energy efficient technologies implementation can become an important source of information for Ukrainian construction specialists, which will significantly improve the energy efficiency of new buildings, reduce energy dependence on critical infrastructure, save money for civilians and improve the comfort of living conditions.
CRITICAL REVIEW OF THE METHODS OF CALCULATING THE STABILITY OF SLOPES
Authors: TIUTKIN O. L. , DUBINCHYK O. I. , KILDIEIEV V. R.
Published: June 2023

Purpose. In many cases, during engineering calculations and design, it is necessary to assess the stability of the built-up area, especially located near slopes. To carry out a critical review of methods for calculating the stability of landslide-prone slopes. Methodology. Variants of methods for calculating the stability of slopes by different authors have been considered. There are many methods for calculating the stability of slopes, all of them are reduced to three basic classes of methods: limit equilibrium methods; finite element method; combined methods. During stability testing, the most common engineering methods are based on force diagrams of the balance of soil massifs. One of the most important issues in the calculation of stability is the correct choice of the surface on which the displacement of the soil is possible. Findings. The choice of certain methods is primarily determined by the type of shearing process and the mechanism of possible displacement of shearing masses. Each original method of calculation is characterized by its original system, obtained in this method using one or another assumption, the necessity of which is related to the static uncertainty of the task. Originality. Formulas for determining the factor of slope resistance are given for practical use. The analysis of the stability of the landslide slope with the involvement of calculation methods is performed as a component of a comprehensive engineering and geological assessment and forecast of the stability of the landslide slope in natural conditions and considering its intended use. Practical value. In project practice, engineering methods for calculating slope stability are used, which contain various simplifying assumptions. The most common of them is the method of round-cylindrical sliding surfaces, which belongs to the planar problem scheme. Determination of the stability factor is a necessary condition for concluding that the slopes can be used for construction.
MEMORIES OF PROFESSOR R. S. LIPOVSKY
Authors: Lipovsky R. S.
Published: June 2023

Воспоминания доцента Р. С. Липовского
WEAR AND SERVICE LIFE OF RAILS AND WHEELS OF THE ROLLING STOCK
Authors: Karpushenko M. I. , Kotova I. O.
Published: June 2023

The major factors determining the intensity of deterioration of rails and wheels of a rolling stock are determined in the article. The measurements of lateral rails deterioration in curve sites of a way, the factors influencing intensity of deterioration are revealed as a result of the analysis.
TECHNICAL AND ECONOMIC COMPARISON OF MODERN INTERMEDIATE BONDS
Authors: Karpushenko M. I. , Antonov M. I. , Velychko D. V.
Published: June 2023

The comparison of technical and economic parameters of modern intermediate fastenings is made and the prospect of their further development is analysed in this article.
STABILITY OF CONTINUOUS WELDED RAIL UNDER A MOVING TRAIN
Authors: Novakovych V. I.
Published: June 2023

In article the new principle of calculation of a railway track without joints at stability is stated in view of the factor of time and influence of trains.
OPTIONS FOR MAINTENANCE OF THE CURRENT SYSTEMS OF TRACK WITH MECHANIZED COMPLEXES
Authors: Blazhko L. S.
Published: June 2023

The alternative choice questions are considered for the track maintenance by the machine complexes under the transition the track keeping of MPS RF to new management and control systems providing the maintenance expences reduction. The transition takes place in accordance with the general administration and management reorganization of railway transport.
CRITERIA FOR DETERMINING THE PERMISSIBLE SPEED IN CURVES
Authors: Kurhan M. B.
Published: June 2023

The existing criteria of admitted speed definition of movement in curves are analysed, directions of development are specified by consideration of high-speed movement.
INFLUENCE OF SOIL PARAMETERS ON THE VALUE OF THE MODULUS OF THE VERTICAL TRACK ELASTICITY
Authors: Danovych V. D. , Rybkin V. V. , Patlasov O. M. , Bondarenko I. O.
Published: June 2023

The necessity of updating of values of the vertical module of a track elasticity is proved, by taking info account of a sort of the subarade soil its state both thickness of a ballast layer and its state. The numerical rating of parameters influencing the module of the track elasticity is given.
A Design of Obstacle Avoiding Robot
Authors: Bandyopadhyay Asmit , Kundu Akash , Parua Dip , Barik Arijit , Pa Anusmita
Published: June 2023

Obstacle detection and avoidance can be considered as the central issue in designing mobile robots. This technology provides the robots with senses which it con use to troverse in unfamiliar environments without do morging itself. In this paper on Obstacle Avoiding Robot is designed
which can detect obstacles in its path and maneuver around them without marking any collision. It is a robot vehicle that works on Arduino Microcontroller and employs ultrasonic distance censor to detect obstacles. The Arduino board was selected as the microcontroller platform and its Software
counterpart, Arduino software, was used to carry out the programming. Being a fully autonomous robot, it successfully maneuvered in unknown environ- ments without any collision. The hardware used in this project is widely available and inexpensive which makes the robot easily replicable.
Poseidon: Surface Water Garbage Collector
Authors: De Arkaprabha , Dutta Samya , Panda Tanistha , Gupta Kunj , Das Subhraneel , Mukhopadhyay Prakriti , Sarkar Riddhiman Dey , Sinha Upalabdha , Das Shirsadip , Chattopadhyay Swastik
Published: June 2023

Increased water pollution has had a negative impact on marine flora and fauna, as evidenced by the extensive coral reef damage, declining aquatic life populations, and extinction of several species. Concerned authorities have taken action to control the problem and stop it from growing
worse, although widespread application has not yet been carried out. This is a little gesture on our part to support the cleaning campaign. This boat will be specifically made to remove all surface water waste from water bodies. The boat will successfully clean the water body by collecting
any trash in its course and storing it in its cavity, which will then be emptied manually on the land. Through the use of the custom-made Poseidon software, the boat will be able to change directions. Thus, the primary goal of this remote-control boat is to maintain the cleanliness of the
water bodies around. This is a little effort on our part towards a healthy and pollution-free environment.
Application of Holography: 3D Hologram Projector
Authors: Sharma Sunny , Kimar Nikhil , Singh Rahul , Yadav Rohit , Pal Souvik , Karmakar Sriyansh , Gosh Arpan , Bishi Agnik , Mondal Souvik
Published: June 2023

An electrical tool used to project images is called a projector. They may be able to educate more effectively and make better use of class time as a result. This research focuses on building a DIY small projector. Despite being quite expensive, the projector is very useful for teachers.
Instead of tossing away items which deem to be of no value at all, we thought about creating a projector inexpensively. On the basis of the various experiments we've conducted, we're attempting to recycle those materials to create a small projector. We constructed the projector out of cardboard,
and to check the clarity of the image, we used a magnifying lens and several forms of lighting. and to be aware of the outcomes of our experiments. We used the projector to give small children a little narrative and it was tested during that time. As a consequence, we saw that the kids pay
close attention and seem to like the narrative. We demonstrated that teachers may utilise a DIY tiny projector effectively and affordably, especially when instructing young students.
Down-Regulation of CPEB4 Alleviates Preeclampsia through the Inhibition of Ferroptosis by PFKFB3
Authors: Song Jiao , Yang Hailan
Published: June 2023

Gestational diabetes mellitus (GDM) complicated with preeclampsia can lead to polyhydramnios, ketosis. Herein, we explored that CPEB4 in cancer progression of preeclampsia and its underlying mechanism. All the serum samples were collected from patients with preeclampsia. These was the induction of CPEB4 in patients with preeclampsia. The serum of CPEB4 mRNA expression was positive correlation with Proteinuria, systolic blood pressure and diastolic blood pressure in patients. The serum of CPEB4 mRNA expression was also negative correlation with body weight of infant in patients. The serum of CPEB4 mRNA expression also was negative correlation with GPX4 level and GSH activity level in patients. The serum of CPEB4 mRNA expression was positive correlation with iron content in patients. CPEB4 gene inhibited trophoblast cell proliferation. CPEB4 gene promoted trophoblast cell ferroptosis by mitochondrial damage. CPEB4 gene induced PFKFB3 expression by the inhibition of PFKFB3 Ubiquitination. PFKFB3 inhibitor reduced the effects of CPEB4 on cell proliferation and ferroptosis of trophoblast cell. Taken together, the CPEB4 promoted trophoblast cell ferroptosis through mitochondrial damage by the induction of PFKFB3 expression, CPEB4 as an represents a potential therapeutic strategy for the treatment of preeclampsia or various types of GDM.
AN OPERATIONAL MATRIX APPROACH TO SOLVE A 2D VARIABLE-ORDER REACTION ADVECTION DIFFUSION EQUATION WITH VIETA–FIBONACCI POLYNOMIALS
Authors: Sharma Rashmi , Rajeev
Published: June 2023

A reaction-advection-diffusion equation describes many physical phenomena, such as the transportation of particles,
groundwater pollution, viscoelasticity, and many others. In this study, a well-known fractional operator of variable
order is used to present the space-time variable-order reaction-advection-diffusion equation. The operational matrix of the variable order derivative is developed with the aid of shifted Vieta-Fibonacci polynomials. This operational matrix is used in the approximation of derivatives of variable order to construct residual associated with the considered problem,
and then it is collocated at some points in the domain, which generates a system of non-linear algebraic equations.
Newton's method is applied to solve the obtained system of non-algebraic equations. To validate the precision of the
proposed scheme, some problems are solved by the proposed scheme, and its comparisons are made with the existing
analytical solution, which clearly indicates the improved accuracy of the proposed method. The convergence of the
scheme and error analysis are also discussed in this paper.
Evolution and trends in Polish-Swiss political, economic, cultural and scientific relations after 1989, including participation in international organizations
Authors: Czichos Aleksander
Published: June 2023

Polish-Swiss contacts have a centuries-old tradition of trade, science, culture and diplomacy. The beginning of diplomatic contacts was Poland’s regaining independence in 1918, which resulted in the establishment of official bilateral contacts, which was connected with the development of economic, scientific and cultural cooperation. Contacts between the states continued throughout the interwar period and the period of World War II, but were limited during the Cold War. Mutual contacts were revived after 1989. There were many official and working mutual visits of heads of state, representatives of governments and parliamentary groups. During the meetings, both bilateral and international issues were discussed. In the initial period, the cooperation between Poland and Switzerland was based on bilateral agreements, which – with Poland’s accession to the EU – were replaced by Switzerland-EU agreements. Bilateral cooperation is maintained in the interstate area as well as within international and military organizations.
Financial management control model to improve the profit of micro and small companies in the footwear sector
Authors: Gómez Walter , Rodríguez Ángela
Published: June 2023

The general objective of this research was to determine the relationship between financial management and the profitability of MYPES in the footwear sector, whose type of study was non-experimental, with a correlational and cross-sectional design. We worked with a population of 201 MSEs, obtaining a random sample of 132; reliable and validated questionnaires were used, as well as an interview guide, processing the data through SPSS. Spearman's correlation coefficient was used to assess the relationship between the variables of interest with a significance of 5%. It was identified that 64% of the MSEs know in detail the balance sheet, 26% have an investment plan, 71% know clearly the profitability generated by their enterprise, 39% have a projected cash flow. Finally, a correlation of 0.786 (p-sig= 0.039) was found between financial management control and profitability, concluding that there is a strong positive relationship.
Адаптация среднего класса к изменяющимся социально-­экономическим условиям в период кризиса
Authors: Пишняк Алина , Халина Наталья , Рогачева Александра
Published: June 2023

Ограничения, вызванные распространением вируса COVID‑19, затронули положение широких слоев населения, при этом говоря о группах риска в самом начале пандемии, эксперты особое внимание уделяли именно среднему классу, предрекая его представителям серьезное обеднение в сложившихся условиях. Данная работа посвящена оценке влияния коронавируса и связанных с ним мер социальной политики на доходы и потребление среднего класса, а также анализу механизмов адаптации представителей среднего класса к кризисным условиям, сопровождающимся снижением доходов. В настоящем исследовании использованы два источника информации. На данных Выборочного наблюдения доходов населения и участия в социальных программах (2017) с использованием методов микромоделирования произведены оценки последствий локдауна для занятых, относящихся к среднему классу. В качестве второго источника использованы данные опроса «Изменения в объеме потребления платных образовательных услуг представителями среднего класса и их готовность инвестировать в развитие человеческого капитала», проведенного в 2018 г. Опрос затрагивает тему потребительского поведения представителей среднего класса в условиях кризиса, что в свою очередь позволяет оценить, как средний класс реагирует на падение доходов и какие действия готов предпринимать в такой ситуации. Данные опросов показали, что в результате первой волны пандемии в группе занятых среднего класса не произошло массового перехода в бедность, доходы этой страты в относительном выражении сократились меньше, чем в остальных группах населения. Существенная доля среднего класса в случае падения доходов сокращает расходы на досуг и отдых, однако доступ к этим благам в 2020 г. оказался ограничен, и расходы естественным образом снизились у всех слоев. Более серьезной проблемой является вынужденная экономия на повседневных тратах, а также отсутствие возможности оплатить услуги, связанные с образованием и здоровьем. Попытка оценить позиции среднего класса после начала пандемии, и особенно в условиях ограничительных мер, указывает на то, что внутри страты есть группы повышенного риска, которые не попали в фокус внимания социальной политики, и, в случае ухудшения ситуации в результате пандемии, средний класс может существенно потерять в уровне доходов и качестве жизни.
Ожирение как моральная паника: тематический анализ теоретических и эмпирических публикации в темпоральной перспективе
Authors: Михайлова Оксана
Published: June 2023

Ожирение рассматривается как одна из актуальных социальных проблем. Но не все исследователи придерживаются данной позиции и считают, что избыточный, с медицинской точки зрения, вес в современном обществе является угрозой для здоровья и благополучия отдельных индивидов и социума в целом (критические исследования веса – 'critical weight studies'). В статье проводится тематический анализ публикаций, представляющих одну из оптик социальной проблемы ожирения в темпоральной перспективе. Изучаются исследования ожирения как «моральной паники» на основе англоязычных источников базы научного цитирования Scopus. Делается вывод, что, несмотря на развитие этой теоретико-­методологической традиции в последнее десятилетие, нерешенными остаются вопросы ее культурной универсальности и измерения динамики морализации ожирения.
Study of eban local garlic yield potential using sustainable cultivation technology in the North Central Timor District
Authors: Asep Ikhsan Gumelar , Nikolas Nik , Eduardus Yosef Neonbeni , Marsianus Falo , Paulus Klau Tahuk , Anna Tefa , Jefrianus Nino , Yakobus Pes Agu , Deseriana Bria
Published: June 2023

This study aims to determine the effect of the best types of mulch and organic fertilizer on the growth and yield of local Eban garlic. This research was conducted from May to October 2022 on the land of the Melati Women Farmer Group (WFG), Salu Village, West Miomaffo District, North Central Timor Regency, East Nusa Tenggara, and the Laboratory of the Faculty of Agriculture, University of Timor. The experimental design used was a spit-plot design with three replications. The treatment consists of two factors: The first factor is the use of mulch, which consists of three levels, namely: TO = without mulch; T1 = organic mulch (rice straw mulch); and T2 = inorganic mulch (plastic mulch). The second factor was the use of cow manure, consisting of four levels, namely: P0 = no fertilizer (without treatment), P1 = cow manure (20 t/ha) + rice husk biochar, P2 = cow manure (20 t/ha) + biochar compost, and P3 = cow manure (20 t/ha) + biochar compost tea. The treatment combinations were T0P0, T0P1, T0P2, T0P3, T1P0, T1P1, T1P2, T1P3, T2P0, T2P1, T2P2, and T2P3 with 3 replications, so that 36 units were obtained. The results of the study showed that the combination treatment of straw mulch and cow manure (20 t/ha) plus rice husk biochar gave the best results on the local garlic yield index parameter eban (9.92).
The predictors of occupationally related injury in employees of Pasteur Institute of Iran
Authors: Rouzbeh Bashar , Korosh Holakoyee Nayini , Ramin Mehrdad , Maryam Fazeli , Masoumeh Arab , Nazanin qShabansalmani
Published: June 2023

Background: Needlestick Injuries (NSI) are a critical occupational risk for healthcare workers. Therefore, the present study investigated the incidence and risk factors of NSI among employees of the Pasteur Institute of Iran, one of the largest and oldest biological research institutes in the country, who are at high risk of occupational exposure to biological agents. Methods: This cross-sectional study included all personnel (565 individuals) of the Pasteur Institute of Iran. Participants answered some questions related to demographic and occupational characteristics as well as occupational exposure to blood and biological products, and occupational protection. Findings: A total of 448 questionnaires were completed. The mean age (SD) and work experience of the participants were 35.62 (9.20) and 9.72 (1.30) years, respectively. A total of 150 individuals had a history of NSI. The mean (SD) ages of participants with and without a history of NSV were 37.40 ± 9.03 and 34.41 ± 8.80 years, respectively (p < 0.001). The occurrence of NSI was related to work experience of more than five years and drinking, eating, or smoking while working. In addition, changing gloves while using the telephone was significantly related to reporting the occurrence of NSI to the department manager. Conclusion: Our findings indicated the relatively high frequency of NSI among the respondents. Despite the importance of personnel training, we did not find the occurrence of NSI or reporting it to be related to attending training courses. Hence, designing efficient preventive and protective measures requires the assessment of the attitudes of the mentioned institute’s personnel toward NSI and its prevention and management.
A note on isomorphisms of quantum systems
Authors: Weigt Martin
Published: June 2023

We consider the question as to whether a quantum system is uniquely determined by all values of all its observables. For this, we consider linearly nuclear GB*-algebras over W*-algebras as models of quantum systems.
On Jordan ideals with left derivations in 3-prime near-rings
Authors: En-guady A. , Boua A.
Published: June 2023

We will extend in this paper some results about commutativity of Jordan ideals proved in [2] and [6]. However, we will consider left derivations instead of derivations, which is enough to get good results in relation to the structure of near-rings. We will also show that the conditions imposed in the paper cannot be removed.
Immunohistochemistry Protocol v1
Authors: Chu Hong-Yuan
Published: June 2023

This protocol describes immunohistochemistry.
iNDI Transcription Factor-NGN2 differentiation of human iPSC into cortical neurons Version 2 v1
Authors: Lara Flores Erika
Published: June 2023

Induced pluripotent stem cell (iPSC)-derived neurons are an important tool for studying diverse types of neurodegenerative disorders, including Alzheimer’s Disease, Parkinson’s disease, and related dementias. Understanding the molecular and cellular mechanisms associated with these diseases is an important step in developing new therapeutic targets. Here we describe a robust differentiation protocol in which we expressed the human neurogenin 2 (NGN2) transcription factor under a tetracycline-inducible promoter as previously described (Fernandopulle et al. 2018), with several modifications and using a PiggyBac system for delivery. This differentiation protocol yields high percentages of cortical neuron markers.
Isolation of bacteria and fungi from cheese rind microbiomes v1
Authors: C.P. Weiss Emily
Published: June 2023

This protocol describes how to harvest and stock bacterial and fungal isolates from cheese rind microbial community samples.
Can We Praxize Second Language Teacher Education? An Invitation to Join a Collective, Collaborative Challenge
Authors: Sharkey Judy
Published: June 2023

The purpose of this essay is to begin a conversation on how we might make praxis, or ''praxizing,'' i.e., fostering and sustaining an ongoing dialogical relationship between theory and practice, an integral part of second language teacher education. This project is firmly located in critical sociocultural theories of, and approaches to, language learning and teaching, and requires active, participatory and collaborative inquiries by teacher educators and teacher learners across the multiple levels and stages of teacher learning from entry level courses to teaching practica and beyond. Examples of praxis/praxizing are included as well as some of the challenges to doing this work.

Received: 14-01-09 / Accepted: 31-03-09

How to reference this article:

Sharkey, J. (2009). Can We Praxize Second Language Teacher Education? An Invitation to Join a Collective, Collaborative Challenge. Íkala. 14(2), pp.125-150