bluuebunny/crossref_metadata_2025 huggingface dataset:
Case Based Interactive Class Teaching Mode for Graduate Students
Authors:   Southern Medical University, Guangzhou, China, Yang Yi , Yu Dekuang
Published: March 2022

Interactive teaching is helpful to cultivate the innovative and exploration spirit of postgraduates, because this teaching method has the characteristics of student-oriented, open and equal, facing challenges, learning care, and questioning encouraging. With consideration of the teaching characteristics of the courses, this paper introduces a case-based interactive class teaching mode between instructors and students, and expounds the specific methods of teacher-student interaction, focusing on the case analysis and interaction methods such as heuristic teaching, question and answer mode, and inquiry experience type. Activation of innovative thinking and exploration is the soul of interactive teaching. Teaching based on recessive knowledge often leads to "rich and full" class, which can promote the cultivation of innovative thinking, and promote the course teaching capability to a higher level.
The "Labyrinth" Archetype as Educational Sce-nario in Pre-School Age
Authors:   Department of Education Sciences and Psychology, University of Florence, Italy, Costantini Stefano
Published: March 2022

The labyrinth is a very ancient archetype, widely spread all over the world which has always signified an initiatory journey, a sort of trial. In particular, for preschoolers (5 years old), the labyrinth represents getting in touch with the dark and instinctive part of oneself while at the same time gaining a sense of trust which, thanks to the teacher’s collaboration, serves to be aware and in control of one's instinct. It represents a first experience of oneself in terms of recognition and regulation of emotions, self-efficacy and managing empowerment. During the play-motor activities carried out in this project, with the participation of 72 children attending the last year of nursery school in Florence, the Jungian archetype of the labyrinth was used as a "symbolic container" to bring out emotional experiences beginning with the use of the 5 senses, to encourage the exploration, discovery, identification and personalization of a space where it is possible to "feel good". As a symbolic path, the labyrinth views the child an active subject that explores his or her own limits and strengths through his or her own personal baggage before the transition to primary school.
Managing the COVID-19 Pandemic in a Fragmented Local Government Setting: a Study from Ogan Ilir Regency, Indonesia
Authors: Nomaini Faisal , Nisyak Hoirun , Santoso Anang Dwi
Published: February 2022

The COVID-19 pandemic marks the importance of coordination, cooperation, and collaboration to reduce the virus’ spread and its impacts. Although a lot of literature has explored how the government works during the COVID-19 pandemic, only a few studies have examined it at the local government level. Therefore, this study aims to fill this gap by exploring the local government’s workings and the agencies. This study used narrative qualitative research with the main data source from interviews with the Ogan Ilir Regency COVID-19 Task Force for the Acceleration of Response. This study found that government agencies have not accomplished at the action level despite having a common goal as a condition of coordination. The findings of this study reaffirmed that the silo mentality still exists in the bureaucracy of local government in Indonesia.
Language Anxiety in Online Japanese Speaking Learning: Study on Beginner Level of Japanese Language Students
Authors: Muliadi Muliadi , Danasasmita Wawan , Widianti Susi
Published: February 2022

Anxiety in the language classroom is an affective filter that interferes with input from being used for language acquisition (Krashen, 1982). Moreover, Ellis (2015) stated that anxiety could cause poor learning outcomes. This study aims to investigate 1) level of language anxiety in beginner level of Japanese language students in online learning situations; 2) relation between language anxiety and self-perception; 3) relation between language anxiety and speaking-based learning outcomes; 4) relation between self-perception and speaking-based learning outcomes, and 5) the sources of language anxiety. A survey was administered to 149 Japanese language students from two state universities in Sumatra. There were 67 students in their first year and 82 in the second year. About 20 students participated in the interview. This study adopted the Japanese language anxiety scale developed by Motoda (2000) to measure anxiety level and used the self-perception scale developed by Kitano (2001) to measure students’ perception of speaking ability. The study found that language anxiety in online learning situations was high. Correlation analyses showed a negative correlation between language anxiety and self-perception. If the level of anxiety rises, self-perception will decrease. Meanwhile, there was a positive correlation between self-perception and student speaking-based learning outcomes. Then, if self-perception increases, student outcomes will increase. There was no correlation between anxiety and speaking-based learning outcomes. The study identified that anxiety in online learning activities stems from personal and interpersonal anxiety, beliefs about teachers, classroom procedures, interaction activities, aspects of infrastructures, and aspects of the language test.
Unilateral absence of fibularis tertius: A clinically and evolutionary salient variation
Authors: Verma Poonam , Abrol Girish
Published: March 2022

: Fibularis tertius muscle has always cherished the distinction of being an entirely human structure and as such it has aided to separate man from the lower animals. The morphology of the fibularis tertius (FT) is extremely inconstant.

In the present case we report a rare case of unilateral absence of FT in right foot of a formalin embalmed male cadaver.

The absence of FT may mislead the doctors in performing graft and transplant operations. Hence radiological imaging techniques must be executed to approve the presence of the FT before planning any manoeuvre on foot. Thus, presence or absence of the FT may have a clinical and evolutionary significance that is emphasized in our case reports.
Áreas de desarrollo para intervención en dislexia
Authors: Rodríguez-Cano Sonia , Delgado-Benito Vanesa , Ausín-Villaverde Vanesa
Published: March 2022

La investigación presentada se enmarca dentro del proyecto Europeo Erasmus+ FORDYSVAR, cuyo objetivo principal es contribuir a la inclusión educativa de los estudiantes con dislexia, en edades comprendidas entre los 10 y los 16 años, mediante el uso de la tecnología, concretamente la Realidad Virtual (RV) para mejorar el acceso, la participación y los logros de aprendizaje de los estudiantes con este trastorno de lectoescritura. Se trata de una investigación de corte cualitativo e interpretativo con un carácter descriptivo. Para determinar cuáles son las áreas de desarrollo para la intervención a través de RV, se realizaron entrevistas semiestructuras a grupos de interés (expertos en dislexia, familias y niños con dislexia). Los resultados obtenidos, derivados del análisis de contenido de las entrevistas realizadas y sometido a revisión por expertos, permiten determinar siete áreas de desarrollo a tener en cuenta en el diseño de las actividades incluidas en el software de Realidad Virtual desarrollado en el proyecto FORDYSVAR. El trabajo realizado puede contribuir al avance en la inclusión, tratamiento y rehabilitación de las personas con dislexia a través de la tecnología y concretamente mediante RV, posibilitando un entorno inmersivo y atractivo para desarrollar las habilidades visoespaciales de los estudiantes con dislexia.
Errores en la escritura de adolescentes con alto y bajo rendimiento académico. Un análisis neuropsicológico.
Authors: Bonilla-Sánchez Ma. del Rosario , Alvarado-Cortés Carolina , García-Flores Marco Antonio , Méndez-Balbuena Ignacio
Published: March 2022

El propósito del trabajo fue analizar, desde la neuropsicología Histórico-Cultural, los tipos de errores en la escritura en adolescentes de educación media básica con alto rendimiento académico (ARA) y bajo rendimiento académico (BRA). Con base en el análisis sindrómico propuesto por Luria, se identificó a los mecanismos de regulación y control y de análisis y síntesis espacial global, como mecanismos subyacentes a los tipos de errores presentados por los participantes. Método. Se aplicó un diseño transversal descriptivo. La muestra incluyó 8 adolescentes con ARA y 8 con BRA, de cada uno de los tres grados del nivel de educación secundaria, siendo una muestra total de 48 adolescentes mexicanos. Se aplicaron tareas para evaluar a los mecanismos neuropsicológicos y a la escritura. Los resultados mostraron los tipos de errores de escritura característicos a los mecanismos identificados como deficientes en su nivel funcional, los errores fueron más significativos en el grupo de BRA. Se resaltan la necesidad de corregir las dificultades en la escritura no desde la escritura misma, sino contemplar actividades que favorezcan el desarrollo funcional de los mecanismos deficientes, incluso desde el nivel de la educación básica inicial.
Relações compliance da missão institucional e a utilização de indicadores de desempenho não financeiros em empresas listadas na B3
Authors: Cunha Callado Antonio Andre , Dantas Siqueira Diengo
Published: March 2022

O presente estudo teve como objetivo investigar a associação entre o compliance da missão institucional das empresas brasileiras de capital aberto e a utilização de indicadores de desempenho não financeiros. Para atingir o objetivo proposto foi operacionalizada uma pesquisa descritiva e quantitativa, considerando empresas não financeiras listadas na B3. A missão institucional foi mensurada com base nas características propostas nos estudos de Pearce e David (1987) e David (1989). Já os indicadores de desempenho não financeiros foram mensurados com base na pesquisa Marquezan, Diehl e Alberton (2013), e Vargas Diehl, Ayres, & Monteiro (2016). Dados referentes a nove características associadas à missão, bem como a indicadores não financeiros pertencentes a oito distintos grupos foram coletados nos relatórios anuais e sites institucionais das empresas por meio da análise de conteúdo. A amostra probabilística consistiu em 115 empresas referentes ao exercício fiscal de 2018. A análise da significância das relações foi realizada usando a Prova Exata de Fisher. Os resultados encontrados mostraram evidências acerca da presença de relações entre o compliance da missão institucional e indicadores de desempenho não financeiros, indicando que as empresas analisadas fazem uso destes indicadores para acompanhar o compliance das declarações expressas na missão. Em termos práticos, este estudo contribui ao reforçar a relevância da missão institucional para o alcance dos objetivos e estratégias empresariais e demonstrar que os indicadores de desempenho não financeiros podem ser preferíveis para acompanhar se aquilo que foi declarado na missão está sendo alcançado. Uma nova perspectiva sobre a análise de indicadores não financeiros, foi inserida no contexto das pesquisas que analisam a relação entre missão e desempenho, trazendo contribuições teóricas e fornecendo novos insights para discussões relacionadas ao tema.
Prevalence of Anaplasma marginale in Water Buffaloes (Bubalus bubalis) in the State of Uttar Pradesh, North India
Authors: Bisen Savita , Aftab Andleeb , Jeeva K. , Chandra D. , Raina O.K.
Published: February 2022

Background: Bovine anaplasmosis caused by Anaplasma marginale is highly endemic in tropical and sub-tropical regions of the world where it accounts for huge economic losses to the livestock sector. Approximately 30% of water buffalo (Bubalus bubalis) herds in India are located in Uttar Pradesh (U.P). However in India, most of the research studies on Anaplasma are focused on cattle whereas studies on this pathogen in water buffaloes have been neglected. Therefore, present investigation was undertaken for determining the prevalence of A. marginale infection in water buffaloes in U.P, North India. Methods: In the current investigation during 2017-2019, the prevalence of A. marginale infection in 228 water buffaloes in three districts of North-West U.P was studied by microscopy and by nested-PCR amplification of major surface protein 5 (msp5) gene. Result: Microscopic examination of blood smears of 228 water buffaloes revealed 7.89% animals positive for A. marginale. Conventional PCR of full length major surface protein 5 (msp5) gene detected 29.39% and nested-PCR amplification of this gene detected 64.0% of these animals as positive for A. marginale infection. A high incidence of the infection detected in this study area suggests that water buffaloes may serve as reservoir hosts of A. marginale and play a vital role in the spread of infection to other susceptible animals. However further studies are required on larger buffalo populations for determining the epidemiological status of anaplasmosis in these animals in India.
Financial Stress Relationship with Work Life and Financial Well-Being
Authors: Ozyuksel Suna
Published: March 2022

In the survey, which examines employees’ status with respect to and the sources of stress as well as its effects on the workforce, a version of the “Financial Well-Being Scale” validated to Turkish has been used and stress levels, generalized anxiety, work performance and psychological resilience levels were measured. We have seen that as the age and education levels of the participants increase, their financial well-being levels improve and their financial stress levels decrease. It is understood that when the financial wellbeing improves/financial stress decreases, this leads to decrease in anxiety level, increase in psychological resilience and im-provement in job performance. We also found that even though participants had high income levels, sav-ings/investments, and no debt; they felt high / the highest levels of financial stress mainly due to high inflation, macroeconomic instability, not knowing how to make the right investments to protect their savings against macroeconomic instability and high level of expenses. We have concluded that financial stress causes them to be depressed at work, unable to concentrate on their work and decreases their perfor-mance.
Caractéristiques de production et de sécurité sanitaire du pain - Une revue
Authors: Bossou Théodoric K.
Published: March 2022

Le pain est un élément essentiel dans l’alimentation des hommes depuis des milliers d’années, et certainement plus ; de nos jours ; où les aliments transportables, prêts à consommer, sont omniprésents dans nos habitudes alimentaires. Il est fait essentiellement de farine de blé, de sel, de sucre, d’arômes et d’autres intrants optionnels comme les améliorants. Certains commerçants véreux utiliseraient des produits peu recommandables à la consommation pour accroitre leur gain. Le bromate de potassium est souvent cité parmi ces améliorants indésirables. La présente étude avait pour objectif principal de comprendre le processus de production des pains à base de farine de blé, notamment les risques les avantages qu’ils comportent et à quel niveau. C’est une étude qualitative descriptive basée sur l’exploitation de documents existant sur le pain, et qui a abouti au fait que ce produit alimentaire de base a traversé les époques sans jamais vraiment changer de recette : farine, eau, sel et levure. La matière première de base, la farine de blé, importée par de nombreux pays comme le Bénin ; se distingue par son niveau de polissage, et donc sa teneur en cendres. Ces farines de blé sont riches en matières minérales mais pauvres en matières organiques. Le pain est le résultat de la cuisson de la pâte pétrie et fermentée Le processus de panification est structuré en une succession d’opérations unitaires que sont le pétrissage, le pointage, le pétrissage, le formage, l’apprêt, entrecoupées de phases "passives" que sont la fermentation et enfin la cuisson. La cuisson consiste à fixer la structure de la pâte, préalablement établie au cours du pétrissage et la fermentation, par son exposition à une haute température (généralement 250°C). Au cours de l’étape de la cuisson, une série de transformations physiques, chimiques et biochimiques se produisent simultanément aboutissant au pain. Mais, les procédés de fabrication peuvent engendrer des défauts touchant l’aspect extérieur, le volume, l'aspect de la mie, l’odeur et la saveur. Par rapport à la qualité sanitaire, l’étude a montré que le pain peut contenir des micro-organismes divers et des substances chimiques qui le rendraient nocif au consommateur. Les circuits de transport et de manipulation qui caractérisent la chaîne de vente sont moins rassurants. En somme, le choix du pain devient de plus en plus difficile en raison des craintes de risques sanitaires pour les consommateurs que suscitent les pratiques de malfaçon dans les boulangeries et la qualité de la chaine de distribution et ce, malgré les règlementations qui régissent le secteur.
Prawne kształtowanie się samorządu narodowościowego na Węgrzech na przełomie XX i XXI wieku
Authors: Dobkowski Jarosław
Published: March 2022

Artykuł dotyczy genezy i ewolucji legislacyjnej podstaw prawnych funkcjonowania samorządu narodowościowego na Węgrzech w okresie transformacji ustrojowej. Zagadnienie jest istotne dlatego, że Węgry to jedno z nielicznych państw, w których występuje model tak zwanej autonomii personalnej, a zatem związki mniejszości narodowych mają charakter publicznoprawny. Podobne założenia przyświecały także rozwiązaniom organizacyjnoprawnym występującym w Polsce w okresie dwudziestolecia międzywojennego, co zostało również przedstawione. Jest to tylko jeden z wariantów pozycji prawnoustrojowej mniejszości narodowych w państwie, których ogólna charakterystyka także stanowi przedmiot opracowania. Węgry są też jedynym państwem, w którym występuje wieloszczeblowy polski samorząd narodowościowy.
Samoregulacja działalności gospodarczej i zawodowej. Organizacje samoregulacyjne w prawie rosyjskim
Authors: Małecki Witold
Published: March 2022

Samoregulacja działalności gospodarczej i zawodowej polega na tworzeniu i kontrolowaniu przestrzegania norm kształtujących sposób wykonywania danej działalności przez podmioty prowadzące tę działalność. W prawie rosyjskim samoregulacja realizowana jest przede wszystkim w ramach funkcjonowania organizacji samoregulacyjnych zrzeszających podmioty określonej działalności gospodarczej lub zawodowej. Organizacje samoregulacyjne funkcjonują jako organizacje o dobrowolnym członkostwie oraz organizacje o obowiązkowym członkostwie. W określonych dziedzinach działalności gospodarczej i zawodowej uzyskanie członkostwa w organizacji samoregulacyjnej, uwarunkowane spełnieniem pewnych przesłanek, stanowi prawny wymóg podjęcia danej działalności. Z tej przyczyny organizacje samoregulacyjne o obowiązkowym członkostwie należy uznać za korporacje prawa publicznego. Publicznoprawne znamię tych organizacji odznacza się charakterem transcendentnym, z uwagi na oddolny sposób ich tworzenia.
The Integrated Probiotic Database: a genomic compendium of bifidobacterial health-promoting strains
Authors: Tarracchini Chiara , Viglioli Martina , Lugli Gabriele Andrea , Mancabelli Leonardo , Fontana Federico , Alessandri Giulia , Turroni Francesca , Ventura Marco , Milani Christian
Published: March 2022

Background: The World Health Organization defines probiotics as “live microorganisms, which when administered in adequate amounts confer a health benefit on the host”. In this framework, probiotic strains should be regarded as safe for human and animal consumption, i.e., they should possess the GRAS (generally recognized as safe) status, notified by the local authorities. Consistently, strains of selected Bifidobacterium species are extensively used as probiotic agents to prevent and ameliorate a broad spectrum of human and/or animal gastrointestinal disorders. Even though probiotic properties are often genus- or species-associated, strain-level differences in the genetic features conferring individual probiotic properties to commercialized bifidobacterial strains have not been investigated in detail. Methods: In this study, we built a genomic database named Integrated Probiotic DataBase (IPDB), whose first iteration consists of common bifidobacterial strains used in probiotic products for which public genome sequences were available, such as members of B. longum subsp. longum, B. longum subsp. infantis, B. bifidum, B. breve, and B. animalis subsp. lactis taxa. Furthermore, the IPDB was exploited to perform comparative genome analyses focused on genetic factors conferring structural, functional, and chemical features predicted to be involved in microbe-host and microbe-microbe interactions. Results and conclusion: Our analyses revealed strain-level genetic differences, underlining the importance of inspecting the strain-specific and outcome-specific efficacy of probiotics. In this context, IPDB represents a valuable resource for obtaining genetic information of well-established bifidobacterial probiotic strains.
Views of the taught and the teachers on medical ethics teaching in two universities in Kenya
Authors: Bukusi Elizabeth Anne
Published: February 2022

Medical or clinical ethics provides guidance for health practitioners and has, hopefully, been taught to medical students during training. The teaching of clinical/medical ethics is more important in the current times because of advances in medical science and the different cultural and socioeconomic circumstances in which medicine is practised. This study sought to determine if and how clinical/medical ethics was taught at two Kenyan medical schools by conducting focus group discussions with undergraduate students and key informant interviews with lecturers teaching ethics and academic administrators. While medical/clinical ethics is a part of the medical curriculum approved by the Kenya Medical and Dental Practitioners Council (Board) and is taught during the training, we identified a gap between the theory and application of ethics education. Undergraduates, medical school administrators and lecturers from both institutions acknowledged a lack of role models and mentors, and a need for further training in communication skills since medical ethics has not been made an examinable subject and there has been no formal requirement for training of lecturers teaching ethics. For the short-term, these gaps can be addressed by training lecturers in medical/clinical ethics, and identifying and utilising suitable reference materials, while long-term measures include developing context-appropriate materials for teaching, in addition to nurturing mentorship skills among lecturers for ethical role modeling.
Activities of SB RAS scientific libraries for heritage preservation of Siberian scientists (to the 120th anniversary of T. T. Deulya birth)
Authors: Kustova E. M. , Barash S. M.
Published: March 2022

Libraries of institutions of the Russian Academy of Sciences (RAS) conduct elucidative activities, promoting popularization of knowledge, advancemtnt of the ideas of scientists, propagation of the achievements of regional science through the creation of information resources of their own generation. The Central Scientific Library of the Irkutsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences (CSL INTS SB RAS) maintains the electronic catalog of scientific publications held in its collections, as well as the Consolidated electronic catalog of publications from the collections of libraries of academic research institutes and institutions of Irkutsk and the Irkutsk region. The Central Scientific Library plans to create electronic memorial libraries dedicated to outstanding Siberian scientists.The article presents the results of biobibliographic studies, which made it possible to identify new materials about one of the initiators of the creation of the Branch of the USSR Academy of Sciences in Irkutsk, Taras Timofeevich Deulya (1901–1974), Candidate of Geological and Mineralogical Sciences, Associate Professor of Irkutsk State University (ISU), scientist, teacher and public activist. In particular, the exact date of birth was established, the list of his unpublished works was discovered. Based on the collected material, the website will be created dedicated to the life and work of T. T. Deulya.
Design, Modelling and Tests of a Barycenter Offset Locomotion Mechanism for Cylindrical Robots
Authors: Patiny Océane
Published: March 2022

Various designs of spherical robots using barycenter offset mechanisms were previously reported. This kind of robots offers advantages such as turning in placeor moving in any direction at any time. Yet, the approaches resulting in a balanced robot, which could roll with reduced energy costs once accelerated, are scarce. We introduce anovel robot of this type. The feasibility of the approach is verified on a cylindrical robot. This paper presents an open-source, remotely controlled, robotic cylinder. The robot uses a specifically designed mechanism to displace a mass in its center, which causes the cylinder to roll forwards or backwards. The movement characteristics of the cylinder, as well as the mathematical and physical limitations of the mechanism were studied. An intuitive user interface allows the robot to be controlled through WiFi. This robot was manufactured only with readily available and inexpensive materials, which would make it a suitable platform for education, typically in the fields of physics and engineering.
Models That Link and Suggest Data about Elementary Particles, Dark Matter, and the Cosmos
Authors: Buckholtz Thomas J.
Published: March 2022

We suggest progress regarding the following six physics opportunities. List all elementary particles. Describe dark matter. Explain ratios of dark matter to ordinary matter. Explain eras in the history of the universe. Link properties of objects. Interrelate physics models. We use models based on Diophantine equations.
Advanced Machine Learning Methods for Learning from Sparse Data in High-Dimensional Spaces: A Perspective on Uses in The Upstream of Development of Novel Energy Technologies
Authors: Ihara Manabu , Manzhos Sergei
Published: March 2022

Machine learning (ML) has found increasing use in research on energy conversion and storage technologies, in particular, so-called sustainable technologies. While often ML is used to directly optimize the parameters or phenomena of interest in the space of features, in this perspective, we focus on using ML to construct objects and methods that help in or enable the modeling of the underlying phenomena. We highlight the need for machine learning from very sparse and unevenly distributed numeric data in multidimensional spaces in these applications. After a brief introduction of some common regression-type machine learning techniques, we will focus on more advanced ML techniques which use these known methods as building blocks of more complex schemes and thereby allow working with extremely sparse data and also allow generating insight. Specifically, we will highlight the utility of using representations with sub-dimensional functions by combining the high-dimensional model representation ansatz with machine learning methods like neural networks or Gaussian process regressions in applications ranging from heterogeneous catalysis to nuclear energy.
Clinical and pharmacological analysis of antiseptics used in practical medicine
Authors:   Peoples' Friendship University of Russia (RUDN), Moscow, Russian Federation, Zyryanov S.K. ,   City Clinical Hospital No 24, Moscow Healthcare Department, Moscow, Russian Federation, Baybulatova E.A. ,   Peoples' Friendship University of Russia (RUDN), Moscow, Russian Federation
Published: March 2022

This review is devoted to benzyldimethyl [3-(myristoylamino) propyl] ammonium (Miramistin®), a universal antiseptic developed in the early 1980s by pharmacologists of the Soviet Union within the framework of ‘Space Biotechnology’ programs, and then registered in the Russian Federation in 2007 as a local antiseptic agent. We provide detailed analysis of the results of multiple studies (both in vitro and clinical studies) proving its high antifungal, antibacterial, and antiviral activity. We also describe the main mechanisms of its action, process of its synthesis, degradation, and the impact on the microbiota and environment (biodegradability of Miramistin® reaches 88–93%; the products of its degradation have no genotoxic effects). Miramistin® meets all the requirements in terms of its efficacy and safety; patients tolerate it well. Such a combination of properties enables its successful use for the treatment and prevention of various infectious and inflammatory diseases caused by different pathogens and affecting different anatomical regions not only in adults, but also in children. Key words: antimicrobial, antiseptic, antifungal and antiviral activity, solution for topical application
Hemophagocytic lymphohistiocytosis: mechanisms of development, clinical manifestations, and treatments
Authors: I.A.Kriulin I.A.Kriulin , Kriulin I.A. ,   National Medical Research Center for Children's Health, Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Alexeeva E.I. ,   National Medical Research Center for Children's Health, Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   Russian Association of Pediatric Rheumatologists, Moscow, Russian Federation, Dvoryakovskaya T.M. ,   National Medical Research Center for Children's Health, Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   Russian Association of Pediatric Rheumatologists, Moscow, Russian Federation, Tepaev R.F. ,   National Medical Research Center for Children's Health, Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
Published: March 2022

Hemophagocytic lymphohistiocytosis (HLH), also known as cytokine storm, hemophagocytic lymphohistiocytosis, and macrophage activation syndrome, is a life-threatening disorder caused by a congenital or acquired defect in the cytolytic activity of cytotoxic T-lymphocytes (CD8+) and natural killers, as well as hyperproduction of interleukins-1, -6, -18, and interferon-γ. HLH develops in children with systemic juvenile idiopathic arthritis (sJIA), often resulting in multiple organ failure, and is characterized by a high risk of death. This article discusses the mechanisms underlying the development of primary and secondary HLH and sJIA, as well as clinical and laboratory manifestations of HLH. It summarizes the information on diagnostic criteria and analyzes therapeutic approaches used for HLH. Key words: hemophagocytic lymphohistiocytosis, systemic juvenile idiopathic arthritis, biologicals, rheumatology, children
Antiseptic Irrigation Solutions Used in Total Joint Arthroplasty
Authors: Christopher Zachary K. , Deckey David G. , Pollock Jordan R. , Spangehl Mark J.
Published: March 2022

» There are limited data that directly compare the efficacy of antiseptic irrigation solutions used for the prevention and treatment of periprosthetic joint infections in orthopaedic procedures; there is a notable lack of prospective data.

» For prevention of periprosthetic joint infections, the strongest evidence supports the use of low-pressure povidone-iodine.

» For the treatment of periprosthetic joint infections, delivering multiple solutions sequentially may be beneficial.
Classroom Interaction in Communicative Language Teaching of Public Secondary Schools in Nepal
Authors: Tiwari Trilok Datt
Published: March 2022

Recently there has been a growing number of interests in classroom research primarily focusing on interaction and language learning as these two issues are considered to be essential components in communicative language teaching which is widely practiced today. This current study was aimed to find out the classroom interaction situation and factors affecting it in public Secondary schools of Kanchanpur district, Nepal. The participants of this study were three English language teachers teaching in the secondary level. The researcher used semi-structured interview and observation of video recordings of classes for collecting the data. In analyzing this study, the researcher used types of interaction proposed by Kumaravadivelu (2006) that include: interaction as textual activity, interaction as an interpersonal activity, and interaction as an ideational activity. The findings showed that all types of interaction activities proposed by him were present in the class. The study also revealed that the teacher often dominated, controlled and initiated the interaction. It further showed that there were several affective factors that prevented the teachers from having classroom interaction. The implication of the study is that the teachers should include all three types of interaction activities in the class and maximize group/pair work for effective teaching and learning of language.
Genre Analysis of the Introduction Sections of Newsfile, a Ghanaian TV Talk Show
Authors: Agbaglo Ebenezer , Ayaawan Alimsiwen Elijah , Owusu Evelyn
Published: March 2022

In recent times, the language of mediatized genres has attracted much scholarly attention all over the world. However, little is known about the rhetorical structure and linguistic realisation of television talk shows in Ghana. This study, therefore, examined the Introduction sections of Newsfile, a popular television talk show telecast on JoyNews, a Ghanaian television station, to determine its schematic structure and linguistic realisations. Data for the study comprised five Introduction sections of the Newsfile aired after the 2016 general elections. The data were transcribed and analyzed based on the English for Specific Purposes (ESP) approach to genre analysis.  The findings revealed that the Introduction section of the talk show was characterized by ten moves (Greetings, Naming of Programme, The Seller, Naming the Host, Invitation of Viewers, Introduction of Subject, Signalling Commercial Break, Host’s Address, Introduction of Guests, and Introduction of Sponsors), with the Host’s Address and Introduction of Guests realized by steps. The study also revealed that while some of these moves were obligatory, others were optional. Additionally, it was revealed that there were recursions of some moves. Further analysis revealed the linguistic resources used in each of the moves. This study has implications for scholarship on talk shows especially in sub-Saharan Africa, genre studies, pedagogy, and further research.
EFL Students in English-Medium and EAP Courses in Turkey
Authors: Baturay Meltem Huri , Yastibaş Ahmet Erdost
Published: March 2022

The present study aimed to determine university students’ perceptions regarding EM and EAP courses and how they studied EM and EAP courses and their exams. It was designed as a qualitative study. Eight students participated in the study. The data were collected through semi-structured interviews and analysed by content analysis method. The findings of the study indicated that the students who perform well in EM and EAP courses and who perform well in EM courses but have difficulty in EAP courses are motivated to receive EM courses and have positive attitudes toward EM courses. Yet, the students who perform well in EM and EAP courses are more motivated to receive EAP courses and have more positive attitudes toward EAP courses. The findings also indicated that the ways the students study EM and EAP courses and for their exams have both similarities and differences. The findings were discussed. The pedagogical implications and limitations of the study were explained, and suggestions for further research were made.
EFL Teachers’ Problems and Solutions in Teaching English to Students with Intellectual and Developmental Disability
Authors: Utami Revita Putri , Suharyadi Suharyadi , Astuti Utari Praba
Published: March 2022

Sekolah Luar Biasa (SLB) is a school specialized for students with special needs, particularly students with Intellectual and Developmental Disability (IDD). In Indonesia, the government guarantees that they have the same right to study formally and informally; and to get the best teachers in the teaching and learning process. In English language teaching, however, even qualified teachers have problems while teaching English to students with IDD. Despite the urgency to solve the problems faced by teachers who teach English or a foreign language to special needs students, especially IDD, there are only a few articles covering this topic. This study, which uses a descriptive qualitative method, aims at uncovering the problems and solutions of five English teachers in teaching students with IDD in SLB Pembina Tingkat Nasional Bagian C Malang. In order to obtain the needed data, an observation checklist, a field note, and an interview guide were utilized. The findings revealed that problems faced by the teachers were related to teachers’ English proficiency, methods and media used in teaching, and students’ ability in learning. The teachers used different solutions to overcome the problems, but the most common solution was using repetition in teaching and practicing. This solution was used as the students had difficulties in understanding and remembering the lesson. The other solutions used during the teaching and learning process include YouTube videos, English learning application, posters, and BSE.
Standardization of Mechanical Specific Energy Equations and Nomenclature
Authors: Dupriest Fred , Pastusek Paul , Lai Stephen , Best Bob , Behounek Michael , Cook Bryan , Basarath Wendell , Cutts Chris , Collins Jared , Kamyab Mohammadreza , Moore Dennis , Pulpan Eric , Jeske Austin , Wilson JJ , Sheets Jamie
Published: March 2022

This paper recommends standardized names and equations for the two most common uses of Mechanical Specific Energy (MSE) concepts: "Total MSE" and "Downhole MSE". These names and their equations should be used uniformly in all applications, including electronic drilling recorder (EDR) pick lists, rig site surveillance, engineering surveillance, data analytics, research, and technical publications.

Mechanical Specific Energy, used as a metric for drilling efficiency, is a mathematical calculation of the energy used per volume of rock drilled. The Downhole MSE equation calculates the efficiency of the bit alone, while the Total MSE equation includes both the bit and drill string. Those who use MSE in surveillance or analytics know the negative effects created by the lack of standardization over the years; it is certainly not a new problem.

The lack of standardized nomenclature has resulted in the use of the same name for different equations, or different names are given two equations that are identical. This affects the ability of drill teams to engage vendors in redesign of performance limitations or to communicate new operational practices between teams or rigs. In addition, this standard corrects a mathematical error that is common in calculating the Total MSE.

The concen with the inconsistencies has increased as MSE has become a key element in many automated optimization schemes. Inconsistencies or uncertainties in the basis of MSE values calculated in real time or shared in large data sets will affect the industry's ablity to develop useful analytics or to automate rig control platforms and data-driven decisions.

This paper also includes a discussion of the MSE measurement errors and their effect on calculated values, which is of particular interest to controls engineers and those involved in data analytics. Examples are provided to illustrate how the two different MSE values are used in field operations. Also, a substantial reference list of current and potential future uses of MSE is included to encourage better MSE-based practices to potentially lead to the development of new uses in the future, including automation.

This ad hoc MSE Standardization Committee is a volunteer group with representation from operators, rig contractors, service companies, and data acquisition vendors. The guidance given reflects there shared experienec in utilizing MSE in surveillance and analytics, and the recommended equations are technically correct.
Adsorption and photocatalytic degradation of an industrial azo dye using colloidal semiconductor nanocrystals
Authors: Mohamed Naim Bel Haj , Ouni Sabri , Bouzid Mohamed , Bouzidi Mohamed , Bonilla-Petriciolet Adrian , Haouari Mohamed
Published: March 2022

In this study, mercaptosuccinic acid capped CdSe nanocrystals was successfully synthesized by in-situ medium colloid and used as photocatalyst for the effective photodegradation of methylene blue from aqueous solution under visible light and sunlight irradiations. The particle size and the crystal structure of these nanocrystals were analyzed by different analytical techniques. Dye adsorption prior to photocatalysis using these nanomaterials was studied via the experimental quantification of kinetics and isotherms. These experimental data were modeled including the application of statistical physics theory to analyze the corresponding adsorption mechanism. A maximum adsorption capacity of 27.1 mg/g (80% of dye removal) was observed in 10 min using an initial concentration of 30 mg/L. Statistical physics calculations indicated that the adsorption energy was lower than 40 kJ/mol. It was also established that the dye adsorption was associated to the electrostatic interactions and hydrogen bonding. Overall, the dye removal was a spontaneous, feasible and exothermic process. Adsorption properties of CdSe-MSA nanocrystals improved the dye photodegradation efficiency under visible light thus achieving up to 80% degradation in 60 min. The synergic effect of adsorption and photocatalytic degradation performance was mainly due to the surface area, small size (3.7 nm) and structural defects (selenium vacancies Se, interstitial of cadmium ICd) of nanocrystals, which enhanced the response of these nanomaterials inside the visible range for the photocatalytic activity. In summary, these nanocrystals are promising materials to be used in wastewater treatment under sunlight for the removal of organic compounds like dyes.
Giant Occipital Encephalocele: A Case Report
Authors: Barzegar Hamide , Davoodi Marzieh , Pourarian Shahnaz
Published: March 2022

Giant encephalocele is a rare condition in which the central nervous system structures in any combination protrude through a defect in the skull and the size of the head is smaller than that of the deformity. A few cases are reported globally. We report the case of a 13-days old neonate suffering giant encephalocele, he underwent a successful surgical intervention in a limited-resource setting.
The Influence of Message Framing on Experiential and Material Purchase: The Mediating Role of Perceived Value
Authors: Li Bin , Lei Li , Zhang Kaidi , Wei Haiying , Li Aimei
Published: March 2022

Experiential advantage literature suggests that experiential purchase could make consumer happier and made a recommendation of experience than material purchase. However, most research has focused on the effect of these two types of purchases on their consequences, which ignore the antecedent factors that affect consumers’ consumption decision making. This study discusses when and why would consumers prefer to experiential purchase or material purchase. We test if message framing (such as promotion and prevention) would affect differential types of purchases’ consumption intention or not. In Study 1, participants in prevention condition perceived higher value of material purchase than experiential purchase, then caused they chose material purchase in preference to experiential purchase. In Study 2, participants in the promotion condition perceived higher value of experiential purchase than material purchase, then caused they chose experiential purchase in preference to material purchase. Results suggest that message framing would affect differential types of purchases’ consumption intention through their perceived value.
Conditioned medium from human cord blood mesenchymal stem cells attenuates age-related immune dysfunctions
Authors: Sun Bo , Meng Xianhui , Li Yanlong , Xiao Zhongdang
Published: March 2022

Aging is accompanied with progressive deterioration of immune responses and tissues function. Using 12-month old mice as model, we showed that conditioned medium of human cord blood mesenchymal stem cells (CBMSC-CM) significantly reduced the population percentage of CD3-CD335 + NK and CD4 + CD25 + regulatory T cells in peripheral blood. The CBMSC-CM administration also increased naïve T cells number and restored the ratio of naïve to memory T cells in CD4 + T cells population. These results indicated that CBMSC-CM improved the immune response efficiency of aged mice. Moreover, we also found CBMSC-CM treatment significantly reduced the number of senescent cells in kidney tissues. Finally, we demonstrated that CBMSC-CM remarkably attenuated hydrogen peroxide triggered T cell response and ameliorated oxidative stress induced cellular senescence. All of these data suggest a prominent anti-aging effect of secretome of CBMSCs.
Evaluation of screening tests for autoimmune gastritis in histopathologically confirmed Japanese patients, and re-evaluation of histopathological classification
Authors: Wada Yasuhiro , Nakajima Shigemi , Mori Naoko , Takemura Shizuki , Chatani Rena , Ohara Mariko , Fujii Makoto , Hasegawa Hiroshi , Hayafuji Kiyoyuki , Kushima Ryoji , Murakami Kazunari
Published: March 2022

Background: The aims of the present study are to evaluate non-invasive screening tests for autoimmune gastritis (AIG) and re-evaluate histopathological classification.Methods: We screened candidates of AIG in JCHO Shiga Hospital between May 2012 and January 2020. The screening criteria were as follows: endoscopic O-p atrophy with Updated Kimura-Takemoto classification, 3+ pepsinogen (PG) test, low serum vitamin B12 or elevated serum gastrin with positive anti-parietal cell (PC) or intrinsic factor antibodies. We evaluated the screening criteria in the patients who were histopathologically confirmed as AIG, and re-evaluated histopathological staging in clinical aspects. Results: Twenty-two of 28 (78.6%) patients who met the screening criteria were histopathologically confirmed as AIG. Common clinical findings in the AIG patients were 10x or greater anti-PC antibody, elevated serum gastrin greater than 172 pg/mL and endoscopic atrophy O-1 or greater. The areas under the curve of PG I, PG II and PG I/II ratio were 0.81, 0.29 and 0.98, respectively. Among histopathologically confirmed AIG patients, 4 and 18 patients were histopathologically classified into florid and end stages, respectively, while no patients into early stage. We could not find a significant difference between florid and end stages in the screening items studied. Conclusions: Florid and end stages in histopathological classification are both advanced-stage AIG in clinical aspects. Our screening criteria without biopsy are applicable to screen clinically-advanced AIG with 78.6% positive predictive value. PG I and PG I/II ratio may be useful to screen AIG. However, we may need other criteria to screen early stage of AIG.