bluuebunny/crossref_metadata_2025 huggingface dataset:
POLICY ENTREPRENEURS DAN JARINGAN KEBIJAKAN PENGENTASAN KEMISKINAN DI ERA DESENTRALISASI
Authors: Letor Ronald Philips
Published: January 2022

Salah satu indikator kemiskinan mainstream dalam kebijakan pengentasan kemiskinan di Indonesia adalah kondisi rumah yang ditempati oleh masyarakat. Indikator ini ditetapkan oleh Badan Pusat Statistik untuk menilai kelayakan rumah masyarakat dari bahan bangunan, syarat kesehatan dan kepemilikan. Hal tersebut menggerakan pemerintah pusat dan daerah untuk merumuskan kebijakan perbaikan dan pembangunan rumah layak huni bagi masyarakat berpenghasilan rendah. Alih-alih sebagai usaha pengentasan kemiskinan, policy entrepreneurs telah menegasikan isu arsitektur tradisional berbasis ramah lingkungan, ramah bencana dan hemat energi, sehingga program kemiskinan ini gagal terintegrasi sejak tahap agenda-setting. Penelitian ini menggunakan metode kualitatif dengan pendekatan analisis dokumen untuk mengelaborasi kondisi struktural dan jaringan kebijakan (policy network) yang menyebabkan kegagalan tersebut dan implikasinya melalui studi kasus program Perbaikan Rumah Tidak Layak Huni (Rutilahu) pada masa pemerintahan Gubernur Jawa Barat periode 2013-2018, Achmad Heriawan.
MEMBANGUN KREDIBILITAS PEMERINTAH MELALUI DIGITALISASI PEMERINTAHAN DI ERA POST-TRUTH (STUDI PENGEMBANGAN COMMAND CENTER PEMERINTAH PROVINSI SULAWESI UTARA)
Authors: POLII ANDREAS MIJNDI
Published: January 2022

Perkembangan teknologi dan informatika sekarang ini telah menyentuh seluruh lapisan baik pemerintah, swasta, dan masyarakat secara umum. Perubahan mendasar yang kemudian menjadi tantangan dalam penyelenggaraan pemerintahan adalah berhubungan dengan pemanfaatan teknologi informatika dan keterbukaan informasi publik. Dimana kedua hal tersebut turut mempengaruhi kredibilitas pemerintah di era digital ini. Sehingga penting bagi Pemerintah Provinsi Sulawesi Utara untuk membangun media yang terpercaya dan akuntabel yang menyediakan layanan informasi yang dapat diakses oleh masyarakat. Penelitian ini bertujuan untuk mengetahui bagaimana membangun kredibilitas pemerintah melalui digitalisasi pemerintahan di era post-truth dengan melakukan studi terhadap pengembangan command center Pemerintah Provinsi Sulawesi Utara berdasarkan dua dimensi kredibilitas dengan melakukan observasi, wawancara dan dokumentasi terhadap sumber data yang telah ditentukan. Hasil yang diperoleh menunjukkan bahwa Pemerintah Provinsi Sulawesi Utara sudah melakukan pengembangan command center untuk membangun kredibilitas pemerintah meskipun terdapat beberapa kekurangan seperti fungsi pengambilan keputusan pimpinan yang belum bisa dilakukan secara optimal melalui command center, terbatasnya informasi yang tersedia pada tampilan menu website, belum semua website perangkat daerah terintegrasi website Pemerintah Provinsi Sulawesi Utara, serta dukungan sumber daya manusia pengelola command center dari unsur ASN yang masih terbatas.
IMPLEMENTASI PROGRAM PEMENUHAN HAK KESEJAHTERAAN SOSIAL MELALUI REHABILITASI SOSIAL BAGI PENYANDANG DISABILITAS FISIK DI KABUPATEN KARAWANG
Authors: Aprillia Ananda , Sugiarti Cucu , Aryani Lina
Published: January 2022

Penelitian ini dilatarbelakangi oleh masih sulitnya penyandang disabilitas, khususnya penyandang disabilitas fisik di Kabupaten Karawang mendapatkan kesejahteraan sosial dalam kehidupannya, sebagai bukti bahwa masih kurangnya perhatian Pemerintah Daerah Kabupaten Karawang kepada penyandang disabilitas. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana implementasi program pemenuhan hak kesejahteraan sosial melalui rehabilitasi sosial bagi penyandang disabilitas fisik di Kabupaten Karawang. Penelitian menggunakan metode kualitatif dengan jenis penelitian studi kasus. Teknik pengumpulan data dalam penelitian adalah melalui observasi, hasil wawancara, serta dokumentasi. Hasil penelitian menunjukan bahwa implementasi program pemenuhan hak kesejahteraan sosial melalui rehabilitasi sosial bagi penyandang disabilitas fisik di Kabupaten Karawang sudah berjalan dengan baik namun belum dapat dikatakan optimal. Sebab masih terdapat beberapa permasalahan dalam pelaksanaan program rehabilitasi sosial yang perlu diperbaiki lagi. Hal tersebut harus segera diatasi agar implementasi program tersebut disetiap tahunnya dapat berjalan secara optimal, sehingga penyandang disabilitas fisik di Kabupaten Karawang mudah untuk memperoleh kesejahteraan sosial dalam kehidupannya
PERKEMBANGAN INDUSTRI PENERBANGAN DAN PERTUMBUHAN EKONOMI DI INDONESIA
Authors: Utama Bayu Dananjaya
Published: January 2022

Persaingan bisnis layanan jasa transportasi udara pada saat ini mengalami perkembangan yang sangat pesat. Penelitian ini melihat pengaruh pertumbuhan ekonomi, kepadatan penduduk, dan jumlah transportasi darat provinsi di Indonesia terhadap jumlah penumpang dan jumlah cargo. Studi ini menggunakan data statistik transportasi udara yang dirilis Badan Pusat Statistik (BPS). Metode Regresi yang digunakan menggunakan Fixed Effect. Hasil penelitian ini menunjukkan bahwa Produk Domestik Bruto (PDB) per kapita dan kebijakan pemerintah mengenai tarif batas atas maupun bawah berhubungan positif dan signifikan terhadap jumlah penumpang. Selanjutnya  variabel transportasi darat yang diwakili truk memiliki hubungan yang positif dan signifikan terhadap cargo. Studi ini juga menemukan kebijakan penerapan batas tarif dapat menganggu keseimbangan pasar. Ketika penerapan tarif batas atas dibawah harga keseimbangan dapat menimbulkan excess demand.
KEBIJAKAN PEMERINTAH BAGI PELINDUNGAN DAN KESELAMATAN MASYARAKAT DARI PENULARAN COVID 19 DI INDONESIA
Authors: Elsye Rosmeri
Published: January 2022

Abstrak

Tulisan ini bertujuan untuk mendapatkan gambaran secara jelas sebeberapa jauh, kebijakan Pemerintah bagi perlindungan dan keselamatan masyarakat terhadap dampak covid 19, karena angka penularan sampai bulan februari 2021, terkonfirmasi diatas angka 1 juta positif Masyarakat yang tertular, dan meninggal diatas angka 30.000. lebih warga Masyarakat meninggal akibat covid 19. Sedangkan yang sembuh terkonfirmasi sebanyak 900 jiwa. Akibat semakin banyaknya yang terkonfirmasi positif, dampaknya kepada ketersediaan ruang-ruang isolasi, dan pengobatan sudah mendekati ambang batas yang diperkenan sesuai standar dari WHO, banyaknya orang yang meninggal dunia, berdampak semakin sangat terbatasnya lahan untuk pemakaman. Penulisan ini menggunakan metode deskriptif kualitatif, dengan sumberdata diperoleh dari media cetak, media elektronik dan berbagai literature  lain yang terkait dengan penanganan covid 19. Simpulan Pemerintah telah melakukan berbagai upaya yang ditempuh, dintaranya dengan melakukan recofusing dan relokasi anggaran APBN dan APBD berdasarkan Perpu 1 tahun 2020, tentang Kebijakan Keuangan Negara dan Stabilitasi Sistem Keuangan Negara, terkait penanganan Covid 19 di Indonesia, kebijakan ini ditempuh agar dalam mengatasi dan memberikan bantuan kepada Masyarakat yang terdampak, serta bantuan kepada UMKM dan pemberian insentif perpajakan, khususnya PPh pasal 21 bagi pengusaha terdampak, dan beberapa bantuan lainnya seperti pemberian sembako, Masyarakat yang bergaji dibawah 5 juta setiap bulannya, sehingga dalam pelaksanaannya memiliki dasar hukum yang jelas.

 

Kata Kunci : Kebijakan, Perlindungan, Keselamatan Masyarakat, Pandemi covid 19.
IMPLEMENTASI PERATURAN KEPALA DESA TENTANG BANTUAN LANGSUNG TUNAI (BLT) DANA DESA AKIBAT DAMPAK PANDEMI DI KABUPATEN GARUT PROVINSI JAWA BARAT
Authors: Ginting Arwanto Harimas , Bintang Wira Abdillah
Published: January 2022

This research aims to review the implementation of the Village Cash Direct Assistance policy through village head regulations in poverty reduction since the Covid-19 pandemic in Keresek Village of Cibatu Subdistrict, Garut Regency. The Village Cash Direct Assistance (BLT DD) is one of the government's initiatives in providing subsidies to Indonesians in need. Assistance is offered to address the problems caused by the prolonged Covid-19 pandemic in Indonesia and worldwide. The Covid-19 pandemic does not only interfere with health that results in death. Pandemics force various activities to be stopped so that the impact is widespread, increasing the number of unemployment, hunger, poverty, etc. For this reason, the government provides funds to the community to suppress the increasing problem.  Implementation of village-level policies using village head regulations is still rare. This research used  qualitative methods using Edward III's policy theory of communication, resources, disposition, and bureaucratic structure. Data sources were obtained through interviews and documentation—data analysis by presenting data, reducing data, and withdrawing conclusions. The research result shows that the implementation of Village Cash Direct Assistance in Keresek Village based on Edward III's theory has been implemented judging from the absence of complaints ranging from the data collection process to distribution to recipients under Operational Standard Procedure (OSP).  This research will inform the implementation of policies at the village level made by the village government.

 

Keywords: Village Fund, Policy, Policy Implementation.
THE MILLENNIUM DEVELOPMENT GOALS (MDGS) AND GLOBAL POVERTY: HAVE WE REALLY FAILED?
Authors: Baidhowah Adfin Rochmad
Published: January 2022

MDGs was implemented over the period 2000-2015 by the United Nations along with 189 members states to tackle several crucial issues, namely ‘extreme poverty and hunger, universal primary education, gender equality and woman empowerment, child mortality, maternal health, HIV/AIDS, malaria and other diseases, environmental sustainability and globally developmental partnership’ (United Nations 2014). After 2015, the MDGs which was adopted by 189 members states was evaluated by comparing between the MDGs’ targets and its results. By using archival research data, this paper argues that the MDGs have not really failed in fighting against global poverty, because the MDGs showed a global willingness to alleviate numbers of poverty and the MDGs have achieved prominent improvement.
PENDEKATAN TECHNOLOGY ACCEPTANCE MODEL (TAM) DALAM MENGANALISIS MINAT PERILAKU PENGGUNAAN E-MONEY PADA MAHASISWA UIN SUNAN GUNUNG DJATI BANDUNG
Authors: Ikhsan M
Published: January 2022

Meningkatnya mobilitas masyarakat mengakibatkan munculnya keinginan untuk melakukan kegiatan transaksi menjadi lebih mudah, efektif dan efisien namun tetap aman. Salah satu hasil dari perkembangan FinTech yang bisa dirasakan saat ini oleh masyarakat yaitu adanya perubahan bentuk uang, baik uang kertas maupun uang logam yang mulai digantikan oleh electronic money atau e-money. Tujuan dari penelitian ini adalah untuk menganalisis faktor-faktor yang mempengaruhi minat untuk menggunakan e-money di kalangan mahasiswa UIN SGD Bandung. Dalam penelitian ini teori penerimaan yang digunakan yaitu modifikasi dan pengembangan dari teori Technology Acceptance Model yang berfokus pada tiga faktor yaitu faktor persepsi manfaat, persepsi kemudahan penggunaan, serta persepsi risiko. Metode dalam penelitian ini adalah kuantitatif dengan teknik analisis data menggunakan teknik analisis deksriptif dan menggunakan analisis regresi linier berganda. Penelitian ini menggunakan 380 responden dengan hasil persepsi manfaat, persepsi kemudahan penggunaan, dan persepsi risiko baik secara parsial maupun simultan berpengaruh positif dan signifikan terhadap minat penggunaan e-money.

 

Kata Kunci: Technology Acceptance Model (TAM), Perceived Usefulness, Perceived Ease of Use, Behavioral Intention dan E-Money
IMPLEMENTASI WEBSITE DESA DALAM PEMBERIAN PELAYANAN INFORMASI PEMBANGUNAN
Authors: Akbar Muhammad Fikri , Jaya Fery Hendi , Putubasai Erwin
Published: January 2022

Teknologi Informasi Komunikasi (TIK) untuk perubahan kehidupan dan pertumbuhan ekonomi di daerah pedesaan. Berdasarkan hal tersebut website desa sebagai media Pelayanan informasi pembangunan, yang merupakan salah satu jenis layanan dari sistem e-Government. Hal tersebut menjadi penting, karena semakin seriusnya pihak pemerintah dalam mengembangkan sistem e-Government di Indonesia, semakin tingginya persentasi pengguna internet di Indonesia. Penelitian ini bertujuan untuk melihat implementasi website desa dalam upaya pemberian pelayanan informasi pembangunan pada masyarakat desa. Electronic Governmnet merupakan suatu proses sistempemerintahan dengan memanfaatkan Information Communication AndTechnology (ICT) sebagai alat untuk memberikan kemudahan proses komunikasidan transaksi kepada warga masyarakat, organisasi bisnis dan antara lembaga pemerintah serta stafnya, sehingga dapat dicapai efisiensi, efektivitas, transparansi dan pertanggungjawaban pemerintah kepada masyarakatnya (Hartono & Mulyanto, 2010). Penelitian ini menggunakan pendekatan kualitatif yang diharapkan mampu menghasilkan suatu uraian mendalam tentang  ucapan, tulisan, dan tingkah laku yang dapat diamati dari suatu individu, kelompok, masyarakat, dan organisasi tertentu dalam konteks setting tertentu yang dikaji dari sudut pandang yang utuh, komprehensif, dan holistik (Bogdan dan Taylor, 1992). Website hanura.desa.id cukup efektif sebagai media penyebaran informasi pembangunan desa, baik efek dalam kajian komunikasi massa (kognitif, afektif, dan konatif) maupun komunikasi interpersonal (keterbukaan, empati, dan sikap mendukung).

 

Keywords: e-Government, website desa, informasi, pembangunan
Pengaruh Keadilan, Jenjang Karir Terhadap Disiplin Kerja sebagai Variabel Intervening pada Aparatur Sipil Negara di Kabupaten Pasaman
Authors: Isnaini Muhammad
Published: January 2022

Penelitian ini bertujuan untuk menganalisis semangat kerja pada Aparatur Sipil Negara Sekretariat Daerah Kabupaten Pasaman dengan melihat pengaruh variabel keadilan terhadap semangat kerja dan pengaruh variabel jenjang karir terhadap semangat kerja dengan menggunakan variabel disiplin kerja sebagai variabel intervening. Jenis penelitian ini adalah penelitian kausal komparatif. Populasi dalam penelitian ini adalah seluruh pegawai Aparatur Sipil Negara Sekretariat Daerah Kabupaten Pasaman dari semua sub bagian instansi yang berjumlah 100 orang. Dalam penelitian ini digunakan metode sensus yaitu dengan memberikan kuesioner pada seluruh populasi yang berjumlah 100 orang yang terdiri dari semua pegawai sub bagian instansi. Teknik analisis data dalam penelitian ini menggunakananalisis SEM (Structural Equation Modelling) yang dioperasikan berbasis Partial Least Square (PLS) dengan alat bantu SmartPLS 3.0. Hasil dari penelitian menunjukkan bahwa variabel keadilan berpengaruh positif dan tidak signifikan terhadap semangat kerja secara tidak langsung, jenjang karir berpengaruh positif dan signifikan terhadap semangat kerja dengan disiplin kerja sebagai variabel mediasi, dengan keadilan yang merata dan adanya peningkatan jenjang karir bagi pegawai dapat membuat semangat kerja pegawai menjadi lebih baik pada Sekretariat Daerah Kabupaten Pasaman.
Analisis Dimensi Kinerja Organisasi Publik pada Dinas Pendidikan dan Kebudayaan Kota Dumai
Authors: Erlianti Dila , Fajrin Irma Novita
Published: January 2022

Dalam pencapaian kinerja, masih ditemukan gejala masalah yaitu,masih terdapat beberapa program dan kegiatan yang tidak tercapai sesuai dengan target kerja yang ditetapkan pada Dinas Pendidikan dan Kebudayaan Kota Dumai dan Masih terdapat sarana dan prasarana pada Dinas Pendidikan dan Kebudayaan Kota Dumai yang dalam kondisi tidak baik dan tidak dapat difungsikan. Rumusan masalah penelitian ini yaitu: Bagaimana Dimensi Kinerja Organisasi Publik Pada Dinas Pendidikan dan Kebudayaan Kota Dumai. Tujuan penelitian ini adalah untuk mengetahui Dimensi Kinerja Organisasi Publik pada Dinas Pendidikan dan Kebudayaan Kota Dumai dan untuk mengetahui faktor pendukung dan faktor penghambat yang mempengaruhi dimensi kinerja pada Dinas Pendidikan dan Kebudayaan Kota Dumai. Hasil penelitian tentang Analisis Dimensi Kinerja Organisasi Publik Pada Dinas Pendidikan dan Kebudayaan Kota Dumai dikategorikan Cukup Baik. Adapun faktor pendukung Dimensi Kinerja Organisasi. Publik Pada Dinas Pendidikan dan Kebudayaan Kota Dumai yaitu: Responbilitas dan Akuntabilitas. Sedangkan faktor penghambat adalah masih kurangnya Produktivitas dan masih kurangnya Responsivitas pegawai pada Dinas Pendidikan dan Kebudayaan Kota Dumai.
Evaluasi Implementasi Pelimpahan Kewenangan Bupati kepada Camat Berdasarkan Peraturan Bupati Nomor 42 Tahun 2004 di Kecamatan Sukasari
Authors: Alfandi Alfandi
Published: January 2022

Penelitian ini bertujuan untuk mengevaluasi dari implementasi kebijakan pelimpahan sebagian kewenangan dari Bupati Sumedang di Kecamatan Sukasari yang didasarkan Peraturan Bupati Nomor 42 Tahun 2004. Implementasinya menggunakan aktivitas pengorganisasian, interpretasi dan aplikasi. Sedangkan evaluasinya menggunakan kriteria efektivitas, efesiensi, kecukupan, perataan, responsivitas dan ketepatan. Metode yang digunakan adalah penelitian deskritif kualitatif dengan pendekatan studi kasus. Teknik mengumpulkan data dan informasi dengan memakai teknik wawancara  dan studi dokumentasi. Data dan informasi diperoleh melalui sumber data yang relevan,  dimana dalam penelitian ditetapkan informan sebanyak 16 orang. Teknik analisa data yang digunakan dalam penelitian ini adalah menyeleksi data, mengklasifikasi data dan interpretasi data. Berdasarkan analisis diperoleh hasil bahwa penerapan pola yang seragam di Kecamatan Sukasari dimana tidak semua kewenangan terlaksana dengan baik. Kualitas dari pegawai kecamatan masih kurang. Koordinasi antara pihak kecamatan dengan UPTD/ Dinas Daerah Kabupaten  belum berjalan maksimal. Sosialisasi kebijakan pelimpahan kewenangan kepada masyarakat belum berjalan maksimal. Kurangnya dukungan sarana dan prasarana serta anggaran dalam implementasi kebijakan pelimpahan sebagian kewenangan.
The Existence of One-Way Functions
Authors: Vega Frank
Published: January 2022

Under the assumption that there exist one-way functions, then we obtain a contradiction following a solid argumentation and therefore, one-way functions do not exist by contraposition. Hence, function problems such as the integer factorization of two large primes can be solved efficiently. In this way, we prove that is not safe many of the encryption and authentication methods such as the public-key cryptography. It could be the case that $P = NP$ or $P \neq NP$, even though there are no one-way functions. However, this result proves that $P = UP$.
PENGARUH PESAN NONVERBAL BUZZER DI MEDIA SOSIAL TERHADAP MINAT BELI
Authors: Naning Salman , Haloho Heppy New Year , Agustia Emi
Published: January 2022

Kehadiran teknologi menuntut terjadinya perubahan dalam penyampaian pesan dan melahirkan perkembangan media baru, seperti kehadiran media social. Media sosial memungkinkan siapapun dapat memproduksi pesan. Pesan-pesan yang disajikan beraneka ragam seperti pesan teks, gambar, video, suara. Apapun dapat dilakukan oleh entitas menjadi pesan dan akan dibagikan di media sosial. Penelitian ini ingin mengetahui seberapa besar pengaruh pesan nonverba buzzer di media sosial terhadap minat beli. Dengan menggunakan paradigma positivistik, pendekatan kuantitatif. Dengan menggunakan teori sistem non verbal. Peneliti mengungkap  pengaruh kode-kode nonverbal dapat mempengaruhi minat beli konsumen  sejumlah  48,6 persen.Sedangkan sisanya sebanyak 51,4 persen pengaruh dari faktor lainnya.
ANALIS MANAJEMEN HUMAS DALAM PENANGANAN COVID-19
Authors: Kede Adrian , Sultan Muh. Iqbal , Karnay Sudirman
Published: January 2022

Humas merupakan salah satu elemen yang menentukan kampanye kebijakan pemerintah dalam penanganan Covid-19, namun faktanya masih ada sebagian masyarakat yang tidak mengetahui kebijakan penanganan Covid-19. Penelitian ini bertujuan untuk menganalisis bagaimana Humas dalam mengkampanyekan kebijakan penanganan Covid-19. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan pendekatan studi kasus. Hasil penelitian menunjukkan Manajemen Humas Pemerintah daerah Kabupaten Banggai dalam merespon penanganan Covid-19 melalui empat tahapan utama, yaitu: 1) Identifikasi masalah; 2) perencanaan dan program; 3) melaksanakan dan mengkomunikasikan; 4) evaluasi program. Selanjutnya media yang digunakan dalam mengkampanyekan kebijakan berupa media cetak (koran), media elektronik (radio), media sosial (Facebook, Instagram, dan Whatsapp), spanduk dan pola komunikasi konvensional (melalui rumah ibadah, balai pertemuan umum).
REPRESENTASI MAKNA HARDINESS DALAM IKLAN BISKUAT VERSI MY BUDDY
Authors: Sadeli Helda Handayani , Abidin Zainal , Nayiroh Luluatu
Published: January 2022

Iklan Biskuat versi My Buddy merupakan iklan yang menampilkan sisi Hardiness atau kepribadian tangguh dalam tokoh pemeran utama yaitu anak tunarungu. Iklan Biskuat versi My Buddy berbeda dari iklan-iklan sebelumnya, sosok anak tunarungu yang memperlihatkan kekuatan hati dan menahan diri ketika mengalami bullying di sekolah pada tingkat Sekolah Dasar (SD). Saat ini marak terjadinya kasus pembulyan di indonesia terutama pada anak sekolah. Dengan adanya iklan Biskuat ini mengajarkan bagaimana kita untuk bersikap dan melawan pembulyan dengan kepribadian yang tangguh. Berdasarkan pernyataan di atas peneliti tertarik untuk melakukan peneleitian iklan ini dengan judul Representasi Makna Hardiness dalam Iklan Biskuat versi My Buddy. Tujuan dari penelitian ini untuk mengetahui makna denotasi, konotasi, dan mitos mengenai Hardiness yang dipresentasikan oleh iklan Biskuat versi My Buddy. Metode penelitian ini menggunakan metode kualitatif dengan analisis semiotika Roland Barthes. Hasil penelitian yang diperoleh dalam penelitian ini bahwa Hardiness adalah kepribadian tangguh yang mampu menahan setiap tekanan dalam diri setiap individu, selain itu orang yang mengalami difabel tidak berarti lemah, terlihat kuat dan berani tidak mesti menyakiti orang lain dan peran orang tua dalam tumbuh kembang pada anak sangat dibutuhkan
Occupational Stress: Associated Factors, Related Symptoms, and Coping Strategies Among Secondary School-heads
Authors: Suleman Qaiser , Zeb Khattak Alam , Hussain Ishtiaq
Published: January 2022

This study examined occupational stress, its related symptoms, associated factors, and coping strategies among heads of secondary schools in Kohat Division, Pakistan. A sample of 101 secondary school-heads was taken using a multistage sampling technique. Occupational Stress Index (Shrivastava & Singh, 1981) followed by four open-ended questions was used to investigate the study variables. Findings revealed that heads of secondary schools were occupationally stressed in their workplace. The most associated factors causing occupational stress were poor compensation, work overload, lack of effective advancement and promotion policy, poor implementation of education policy, lack of basic facilities, political interference, and under-participation. Several symptoms such as headaches, alterations in blood pressure, and digestive problems, were found to be associated with an increased risk of occupational stress. Furthermore, various related perceived physiological, psychological, and behavioral consequences were found to be caused by stress at work. Findings suggest that a comprehensive strategy promoted by the education department should be recommended for reducing stress among secondary school-heads and improving their wellbeing and other health-related conditions at the workplace.
APLIKASI PEMERIKSAAN KESEHATAN KONSUMEN HERBALIFE BERBASIS ANDROID
Authors: Rusdiana Lili , Ghani Putra Fathir Anugrah , Faiqotul Himmah Elok
Published: January 2022

Health services are one type of public service that is the spearhead of public health development. People who care about health have started to establish health communities such as healthy homes or nutrition houses such as the Herbalife healthy home. Herbalife's healthy home uses a special scale, the tanita scale, as an indicator of consumer fitness and health. With technological developments, an application is needed that can help carry out consumer health checks. The methodology used in making this application is the prototype model. The programming language used is Kotlin. Meanwhile, the tools and editors used are Android Studio. The method used in data collection in this study is the method of literature, observation, and interviews. With this built application, it can help in determining the health of consumers from several parameters used in this study, including body fat, belly fat, cell age, and health. The output of these parameters is then used as input for the application being built.

 

Layanan kesehatan menjadi salah satu jenis layanan publik yang merupakan ujung tombak dalam pembangunan kesehatan masyarakat. Komunitas masyarakat yang peduli kesehatan mulai mendirikan komunitas kesehatan seperti rumah sehat atau pun rumah nutrisi seperti rumah sehat Herbalife. Rumah sehat Herbalife menggunakan timbangan khusus yakni timbangan tanita sebagai alat indikator kebugaran dan kesehatan konsumen. Dengan perkembangan teknologi, maka dibutuhkan aplikasi yang bisa membantu melakukan pemeriksaan kesehatan konsumen. Metodologi yang digunakan dalam pembuatan aplikasi ini yakni model prototype. Bahasa pemrograman yang digunakan yaitu Kotlin. Sedangkan tools dan editor yang digunakan yakni Android Studio. Metode yang digunakan dalam pengumpulan data dalam penelitian ini yakni metode kepustakaan, observasi, dan wawancara. Dengan adanya pengembangan aplikasi ini, maka dapat membantu dalam menentukan kesehatan konsumen dari beberapa parameter yang digunakan antara lain yakni lemak tubuh, lemak perut, usia sel, dan kadar air. Output dari beberapa parameter tersebut kemudian dijadikan sebagai input untuk aplikasi yang dibangun.
Enhanced Spontaneous Antibacterial Activity of δ-MnO2 by Alkali Metals Doping
Authors: Yan Yali , Jiang Ning , Liu Xin , Pan Jie , Li Mai , Wang Chunrui , Camargo Pedro H. C. , Wang Jiale
Published: January 2022

Recently, the widespread use of antibiotics is becoming a serious worldwide public health challenge, which causes antimicrobial resistance and the occurrence of superbugs. In this context, MnO2 has been proposed as an alternative approach to achieve target antibacterial properties on Streptococcus mutans (S. mutans). This requires a further understanding on how to control and optimize antibacterial properties in these systems. We address this challenge by synthesizing δ-MnO2 nanoflowers doped by magnesium (Mg), sodium (Na), and potassium (K) ions, thus displaying different bandgaps, to evaluate the effect of doping on the bacterial viability of S. mutans. All these samples demonstrated antibacterial activity from the spontaneous generation of reactive oxygen species (ROS) without external illumination, where doped MnO2 can provide free electrons to induce the production of ROS, resulting in the antibacterial activity. Furthermore, it was observed that δ-MnO2 with narrower bandgap displayed a superior ability to inhibit bacteria. The enhancement is mainly attributed to the higher doping levels, which provided more free electrons to generate ROS for antibacterial effects. Moreover, we found that δ-MnO2 was attractive for in vivo applications, because it could nearly be degraded into Mn ions completely following the gradual addition of vitamin C. We believe that our results may provide meaningful insights for the design of inorganic antibacterial nanomaterials.
Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves’ Disease
Authors: Zhou Fangyu , Wang Xin , Wang Lingjun , Sun Xin , Tan Guiqin , Wei Wenwen , Zheng Guangbing , Ma Xiaomin , Tian Dan , Yu Hongsong
Published: January 2022

Graves’ disease (GD) is a well-known organ-specific autoimmune disease characterized by hyperthyroidism, goiter, and exophthalmos. The incidence of GD is approximately 2.0–3.0% in China and 0.5–2.0% in Western countries. Due to the complex pathogenesis and etiology of GD, current treatment methods have great side effects that seriously endanger human health. Therefore, it is particularly important to understand the pathogenesis of GD. Various studies have shown that genetics, epigenetics, cellular immunology, and gut microbiota are all involved in the development of GD. Genetically, CD25 gene and VDR gene polymorphisms are involved in the development of GD by increasing the ratio of Th17/Treg cells. Epigenetically, miR-23a-3p and lncRNA-MEG3 lead to Th17/Treg imbalance and participate in the progression of GD. Moreover, commensal microbe deletion can disrupt Th17/Treg balance and participate in the occurrence of GD. The imbalance of Th17/Treg cells induced by genetics, epigenetics, and gut microbiota plays a vital role in the pathogenesis of GD. Therefore, this article reviews the role of genetics, epigenetics, cellular immunology, and gut microbiota in the pathogenic mechanism of GD. This may lead to the development of novel therapeutic strategies and providing promising therapeutic targets.
Challenges, Inquiry, and Recommendations: Effective COVID-19 Vaccine Management in the Face of Public Mistrust and Concern
Authors: Caron Rosemary M. , Dorsey M. Girard
Published: January 2022

By examining concerns about safety, compliance, and distribution through an interdisciplinary approach of public health and history, we argue that historical and contemporary mistrust of immunizations serves to challenge the successful management of a COVID-19 vaccine program in the U.S. Unique circumstances surrounding the development of a COVID-19 vaccine, including pressure for rapid production, unclear communication from public health officials, and existing resistance to behavioral protective public health policy measures (e.g., mask-wearing) complicate widespread vaccine adoption. Currently, the demand for first and second COVID-19 vaccine doses, as well as the COVID-19 booster, continues to fluctuate in the U.S. population as COVID-19 variants continue to emerge. This hesitancy has resulted in a stalled vaccination program and the absence of herd immunity. To support the successful management of a vaccine program, we recommend public health education and communication measures that can be tailored to local community needs while preparing realistic public expectations surrounding the efficacy of a COVID-19 vaccine. A tailored approach may reduce vaccine hesitancy in American society. The perspectives offered herein present a pathway that is applicable to the current COVID-19 vaccine management program in the U.S., other global locations, and future pandemics.
The Association Between COVID-19 and Thyroxine Levels: A Meta-Analysis
Authors: Chen Yiru , Li Xiuneng , Dai Yu , Zhang Jingjing
Published: January 2022

Objectives

Recently, a number of reports have described the potential relationship between COVID-19 and thyroid hormones, but the results were conflicting. We performed a meta-analysis to evaluate the effect of the severity of COVID-19 on thyroid-related hormones and the effect of thyroid-related hormones on the outcome of COVID-19 in order to try to confirm the association between the serum levels of free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) and the severity or mortality of coronavirus-19 patients.

Methods

The methodology was already registered in the International Prospective Register of Systematic Reviews (PROSPERO) database, and the protocol number is CRD42021269246. Systematic searches were carried out on the Cochrane Library, Embase, PubMed and Web of Science databases on November 15, 2021. We set up the literature search strategy based on the following keywords: [(T3 OR FT3 OR triiodothyronine) or (T4 OR FT4 OR thyroxine) or (TSH or thyrotropin)] and (COVID-19 OR SARS-CoV-2), without time restrictions.

Results

Twenty studies satisfied the inclusion/exclusion criteria and were included in the meta-analysis. A total of 3609 patients were enrolled in the study. From the analysis of the included studies, the incidence of thyroid-related hormone abnormalities was higher in patients with severe COVID-19, and the serum levels of FT3 and TSH were lower than those of patients with nonsevere COVID-19. However, the difference in the FT4 levels was not significant. Similar characteristics were shown between survivors and nonsurvivors. In addition, the outcomes of the meta-analysis showed that patients with abnormal thyroid-related hormones had greater mortality.

Conclusions

Low FT3 serum levels, low FT4 serum levels and low TSH serum levels may increase the mortality of COVID-19 patients during admission. On the other hand, the higher the severity level of COVID-19, the higher the probability of decreases in the FT3, FT4, TSH levels.
Transmission of Antibiotic-Resistant Escherichia coli from Chicken Litter to Agricultural Soil
Authors: Fatoba Dorcas Oladayo , Amoako Daniel Gyamfi , Abia Akebe Luther King , Essack Sabiha Yusuf
Published: January 2022

A growing concern regarding the use of animal manure as fertilizer is the contamination of soil, plants, and the environment with a variety of antibiotic-resistant and pathogenic bacteria. This study quantified and characterized the antibiotic resistance profiles of Escherichia coli in soil before and after chicken litter application to determine the impact of manure on the soil resistome. Litter and soil samples were collected from a sugarcane field before and after litter application. E. coli was isolated and quantified using the Colilert®-18/Quanti-tray® 2000 and 10 randomly selected isolates from the positive wells of each Quanti-tray were putatively identified on eosin methylene blue agar. Real-time PCR was used to confirm the isolates by targeting the uidA gene. Antibiotic susceptibility test against 18 antibiotics was conducted using the disk diffusion method, and the multiple antibiotic resistance index was calculated. Soil amendment with chicken litter significantly increased the number of antibiotic-resistant E. coli in the soil. Among the 126 E. coli isolates purified from all the samples, 76% showed resistance to at least one antibiotic, of which 54.2% were multidrug-resistant (MDR). The highest percentage resistance was to tetracycline (78.1%), with the least percentage resistance (3.1%) to imipenem, tigecycline, and gentamicin. The isolates also showed resistance to chloramphenicol (63.5%), ampicillin (58.3%), trimethoprim-sulfamethoxazole (39.6%), cefotaxime (30.2%), ceftriaxone (26.0%), cephalexin (20.8%), cefepime (11.5%), amoxicillin-clavulanic acid (11.5%), cefoxitin (10.4%), Nalidixic acid (9.4%), amikacin (6.3%), and ciprofloxacin (4.2%). Of the 54.2% (52/96) MDR, the highest number was isolated from the litter-amended soil (61.5%) and the least isolates from soil samples collected before litter application (1.9%). The relatively higher mean MAR index of the litter-amended soil (0.14), compared to the soil before the amendment (0.04), suggests soil pollution with antibiotic-resistant E. coli from sources of high antibiotic use. E. coli could only be detected in the soil up to 42 days following manure application, making it a suitable short-term indicator of antibiotic resistance contamination. Notwithstanding its relatively short detectability/survival, the application of chicken litter appeared to transfer antibiotic-resistant E. coli to the soil, enhancing the soil resistome and highlighting the consequences of such agricultural practices on public health.
Carbon Emission Trading Scheme, Carbon Emissions Reduction and Spatial Spillover Effects: Quasi-Experimental Evidence From China
Authors: Yang Zhaofu , Yuan Yongna , Zhang Qingzhi
Published: January 2022

The carbon emission trading scheme (ETS) is an essential policy tool for accomplishing Chinese carbon targets. Based on the Chinese provincial panel data from 2003 to 2019, an empirical study is conducted to measure the effects of carbon emission reduction and spatial spillover effect by adopting the difference-in-differences (DID) model and spatial difference-in-differences (SDID) model. The research findings show that: 1) The ETS effectively reduced the total carbon emissions as well as emissions from coal consumption; 2) such effects come mainly from the reduction of coal consumption and the optimization of energy structure, rather than from technological innovation and optimization of industrial structure in the pilot regions; and 3) the ETS pilot regions have a positive spatial spillover effect on non-pilot regions, indicating the acceleration effect for carbon emission reduction. Geographic proximity makes the spillover effect decrease due to carbon leakage.
INHBA is a Prognostic Biomarker and Correlated With Immune Cell Infiltration in Cervical Cancer
Authors: Zhao Kaidi , Yi Yuexiong , Ma Zhou , Zhang Wei
Published: January 2022

Background: Inhibin A (INHBA), a member of the TGF-β superfamily, has been shown to be differentially expressed in various cancer types and is associated with prognosis. However, its role in cervical cancer remains unclear.

Methods: We aimed to demonstrate the relationship between INHBA expression and pan-cancer using The Cancer Genome Atlas (TCGA) database. Next, we validated INHBA expression in cervical cancer using the Gene Expression Omnibus (GEO) database, including GSE7803, GSE63514, and GSE9750 datasets. Enrichment analysis of INHBA was performed using the R package “clusterProfiler.” We analyzed the association between immune infiltration level and INHBA expression in cervical cancer using the single-sample gene set enrichment analysis (ssGSEA) method by the R package GSVA. We explored the association between INHBA expression and prognosis using the R package “survival”.

Results: Pan-cancer data analysis showed that INHBA expression was elevated in 19 tumor types, including cervical cancer. We further confirmed that INHBA expression was higher in cervical cancer samples from GEO database and cervical cancer cell lines than in normal cervical cells. Survival prognosis analysis indicated that higher INHBA expression was significantly associated with reduced Overall Survival (p = 0.001), disease Specific Survival (p = 0.006), and Progression Free Interval (p = 0.001) in cervical cancer and poorer prognosis in other tumors. GSEA and infiltration analysis showed that INHBA expression was significantly associated with tumor progression and some types of immune infiltrating cells.

Conclusion:INHBA was highly expressed in cervical cancer and was significantly associated with poor prognosis. Meanwhile, it was correlated with immune cell infiltration and could be used as a promising prognostic target for cervical cancer.
Predictive Value of Triglyceride-Glucose Index for In-hospital Mortality in Patients With Severe Fever With Thrombocytopenia Syndrome: A Multi-Center Observational Study
Authors: Zhang Tingyu , Liu Yuanni , Ge Ziruo , Tian Di , Lin Ling , Zhao Zhenghua , Shen Yi , Yu Xiaoli , Feng Yang , Qiang Chunqian , Duan Jianping , Ma Yanli , Fan Tianli , Zhao Yongxiang , Chen Zhihai
Published: January 2022

Background: Triglyceride-glucose (TyG) index has been proposed as a reliable indicator for insulin resistance and proved to be closely associated with the severity and mortality risk of infectious diseases. It remains indistinct whether TyG index performs an important role in predicting in-hospital mortality in patients with severe fever with thrombocytopenia syndrome (SFTS).

Methods: The current study retrospectively recruited patients who were admitted for SFTS from January to December 2019 at five medical centers. TyG index was calculated in accordance with the description of previous study: Ln [fasting triglyceride (TG) (mg/dl) × fasting blood glucose (FBG) (mg/dl)/2]. The observational endpoint of the present study was defined as the in-hospital death.

Results: In total, 79 patients (64.9 ± 10.5 years, 39.2% female) who met the enrollment criteria were enrolled in the current study. During the hospitalization period, 17 (21.5%) patients died in the hospital. TyG index remained a significant and independent predictor for in-hospital death despite being fully adjusted for confounders, either being taken as a nominal [hazard ratio (HR) 5.923, 95% CI 1.208–29.036, P = 0.028] or continuous (HR 7.309, 95% CI 1.854–28.818, P = 0.004) variate. TyG index exhibited a moderate-to-high strength in predicting in-hospital death, with an area under the receiver operating characteristic curve (AUC) of 0.821 (95% CI 0.712–0.929, P < 0.001). The addition of TyG index displayed significant enhancement on the predictive value for in-hospital death beyond a baseline model, manifested as increased AUC (baseline model: 0.788, 95% CI 0.676–0.901 vs. + TyG index 0.866, 95% CI 0.783–0.950, P for comparison = 0.041), increased Harrell's C-index (baseline model: 0.762, 95% CI 0.645–0.880 vs. + TyG index 0.813, 95% CI 0.724–0.903, P for comparison = 0.035), significant continuous net reclassification improvement (NRI) (0.310, 95% CI 0.092–0.714, P = 0.013), and significant integrated discrimination improvement (0.111, 95% CI 0.008–0.254, P = 0.040).

Conclusion: Triglyceride-glucose index, a novel indicator simply calculated from fasting TG and FBG, is strongly and independently associated with the risk of in-hospital death in patients with SFTS.
Electroacupuncture for the Prevention of Postoperative Cognitive Dysfunction Among Older Adults Undergoing Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Ou Liang , Shen Zhen , Zhang Tiantian , Chen Zehua , Zhang Lin , Xu Daoqing , Kong Dezhong , Qi Qi , Huang Yanchang , Huang Weichen , Meng Yingfu
Published: January 2022

Background: Postoperative cognitive dysfunction (POCD) is a common surgical complication in elderly patients undergoing hip and knee replacement. Electroacupuncture (EA) may have a protective effect on postoperative cognitive function, but relevant evidence remains uncertain.

Objective: To systematically evaluate the evidence of EA for the prevention of POCD after total joint arthroplasty.

Methods: PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), China National Knowledge Infrastructure (CNKI), Wanfang Data, VIP, and Chinese Biomedical Literature Database (CBM) databases were searched until May 1, 2021. Randomized controlled trials (RCTs) in which patients undergoing hip and knee replacement pretreated with EA for preventing POCD were included. The risk of bias was assessed by the Cochrane Collaboration tool. Meta-analysis was performed using Review Manager version 5.4.

Results: A total of 11 RCTs with 949 patients were identified. Meta-analysis showed that compared with controls, EA pretreatment significantly reduced the incidence of POCD at 1, 3, and 7 days and 3 and 6 months after the operation. EA was also superior in improving the Mini-Mental State Examination (MMSE) scores on the third postoperative day, but not on the first postoperative day. Neuron-specific enolase (NSE) and interleukin-1β (IL-1β) in the EA group were significantly lower than that in the control group. There was no difference in S100β between the EA group and the control group. Compared to the control group, tumor necrosis factor-α (TNF-α) levels were not significantly lower in the EA group at postoperative hour 0, while significantly decreased at postoperative hours 24 and 48.

Conclusion: Our results suggest that EA pretreatment is an effective adjunctive therapy for reducing the incidence of POCD for patients receiving total joint replacement surgery. Its effect was embodied in improving the MMSE scores and NSE, IL-1β, and TNF-α levels, whereas it had no significant effect on S100β levels. Meanwhile, the benefits of EA for improving POCD need further strengthening and support from more large-scale, high-quality, and good-homogeneity RCTs.

Systematic Review Registration:https://osf.io/xb3e8.
Single-Photon Emission Computed Tomography/Computed Tomography Image-Based Radiomics for Discriminating Vertebral Bone Metastases From Benign Bone Lesions in Patients With Tumors
Authors: Jin Zhicheng , Zhang Fang , Wang Yizhen , Tian Aijuan , Zhang Jianan , Chen Meiyan , Yu Jing
Published: January 2022

Purpose: The purpose of this study was to investigate the feasibility of Single-Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) image-based radiomics in differentiating bone metastases from benign bone lesions in patients with tumors.

Methods: A total of 192 lesions from 132 patients (134 in the training group, 58 in the validation group) diagnosed with vertebral bone metastases or benign bone lesions were enrolled. All images were evaluated and diagnosed independently by two physicians with more than 20 years of diagnostic experience for qualitative classification, the images were imported into MaZda software in Bitmap (BMP) format for feature extraction. All radiomics features were selected by least absolute shrinkage and selection operator (LASSO) regression and 10-fold cross-validation algorithms after the process of normalization and correlation analysis. Based on these selected features, two models were established: The CT model and SPECT model (radiomics features were derived from CT and SPECT images, respectively). In addition, a combination model (ComModel) combined CT and SPECT features was developed in order to better evaluate the predictive performance of radiomics models. Subsequently, the diagnostic performance between each model was separately evaluated by a confusion matrix.

Results: There were 12, 13, and 18 features contained within the CT, SPECT, and ComModel, respectively. The constructed radiomics models based on SPECT/CT images to discriminate between bone metastases and benign bone lesions not only had high diagnostic efficacy in the training group (AUC of 0.894, 0.914, 0.951 for CT model, SPECT model, and ComModel, respectively), but also performed well in the validation group (AUC; 0.844, 0.871, 0.926). The AUC value of the human experts was 0.849 and 0.839 in the training and validation groups, respectively. Furthermore, both SPECT model and ComModel show higher classification performance than human experts in the training group (P = 0.021 and P = 0.001, respectively) and the validation group (P = 0.037 and P = 0.007, respectively). All models showed better diagnostic accuracy than human experts in the training group and the validation group.

Conclusion: Radiomics derived from SPECT/CT images could effectively discriminate between bone metastases and benign bone lesions. This technique may be a new non-invasive way to help prevent unnecessary delays in diagnosis and a potential contribution in disease staging and treatment planning.
Insightful Advancement and Opportunities for Microbial Bioplastic Production
Authors: Samadhiya Kanchan , Sangtani Rimjhim , Nogueira Regina , Bala Kiran
Published: January 2022

Impetuous urbanization and population growth are driving increased demand for plastics to formulate impeccable industrial and biomedical commodities. The everlasting nature and excruciating waste management of petroleum-based plastics have catered to numerous challenges for the environment. However, just implementing various end-of-life management techniques for assimilation and recycling plastics is not a comprehensive remedy; instead, the extensive reliance on finite resources needs to be reduced for sustainable production and plastic product utilization. Microorganisms, such as bacteria and algae, are explored substantially for their bioplastic production repertoire, thus replacing fossil-based plastics sooner or later. Nevertheless, the utilization of pure microbial cultures has led to various operational and economical complications, opening the ventures for the usage of mixed microbial cultures (MMCs) consisting of bacteria and algae for sustainable production of bioplastic. The current review is primarily focuses on elaborating the bioplastic production capabilities of different bacterial and algal strains, followed by discussing the quintessence of MMCs. The present state-of-the-art of bioplastic, different types of bacterial bioplastic, microalgal biocomposites, operational factors influencing the quality and quantity of bioplastic precursors, embracing the potential of bacteria-algae consortia, and the current global status quo of bioplastic production has been summarized extensively.