bluuebunny/crossref_metadata_2025 huggingface dataset:
A ARGUMENTAÇÃO A PARTIR DE QUESTÕES SOCIOCIENTÍFICAS NA FORMAÇÃO DE PROFESSORES DE BIOLOGIA
Authors: Braga Samuel Santos , Martins Liziane , Conrado Dália Melissa
Published: August 2019

Reconhecendo a importância da argumentação para o Ensino de Biologia, sobretudo ao facilitar a aprendizagem de/sobre ciências, o presente estudo objetivou avaliar conteúdos mobilizados nos argumentos de estudantes de biologia na resolução de questões sociocientíficas (QSC), a partir de uma educação contextualizada por História e Filosofia das Ciências (HFC) e Ciência, Tecnologia, Sociedade e Ambiente (CTSA). Para isso, realizamos uma oficina pedagógica utilizando QSC como casos e atividades de argumentação, envolvendo 22 estudantes do curso de licenciatura em biologia. Para a coleta de dados, utilizamos os argumentos produzidos pelos estudantes. A análise dos dados ocorreu inicialmente com a avaliação estrutural e de conteúdo desses argumentos, tendo como base, respectivamente, os modelos de Toulmin (2006) e Sá (2010). De um modo geral, percebemos que a oficina contribuiu para fomentar o discurso argumentativo, bem como requerer, por parte dos estudantes, a mobilização de vários aspectos do conteúdo. Contudo, notamos ainda argumentos de baixa complexidade e imprecisão nos conteúdos mobilizados. Nesse sentido, uma vez que o uso de QSC tem se mostrado promissor para o desenvolvimento de habilidades argumentativas e de mobilização de conteúdos científicos, em um ensino contextualizado e interdisciplinar, mas que ainda existem dificuldades para esse método efetivar-se na educação científica, ressaltamos a importância e a necessidade da realização de mais estudos sobre argumentação com QSC no ensino de ciências, bem como de maiores investimentos em discussões que abordem aspectos históricos e filosóficos da ciência e relações entre CTSA.
HABILIDADES COGNITIVAS EM PROCESSOS FORMATIVOS DE PROFESSORES DA EDUCAÇÃO BÁSICA NA APRENDIZAGEM BASEADA EM PROBLEMAS
Authors: Coelho Antonia Ediele de Freitas , Malheiro João Manoel da Silva
Published: August 2019

Esta investigação analisa os níveis de habilidades cognitivas desenvolvidos por uma equipe de seis docentes ao solucionarem um problema autêntico, proposto por eles, ao longo de um Curso de Férias desenvolvido na Universidade Federal do Pará. Caracterizamos a investigação de acordo com a abordagem qualitativa, apoiando-nos em suportes metodológicos como diários de campo e videogravações, com decorrente transcrição das falas dos sujeitos para a construção dos dados analisados. Apresentamos o conceito de cognição, bem como as etapas necessárias para que a mente humana alcance o que se pode considerar como habilidade cognitiva. Procuramos ainda analisar de que maneira os níveis de dificuldade, impostos nas perguntas dos monitores, influenciaram na manifestação dessas habilidades. Consideramos também a utilização da experimentação investigativa, como metodologia principal usada no Curso de Férias, destacando que essa envolve algumas etapas que são direcionadas a partir Aprendizagem Baseada em Problemas (ABP). Com base nessa pesquisa, é possível identificarmos que o emprego de atividades experimentais investigativas contribui, consideravelmente, para que as habilidades cognitivas se desenvolvam e manifestem em seus participantes, evidenciando que a metodologia utilizada nesse Curso se aproxima dos objetivos almejados na ABP.
CONCEPCIONES EPISTEMOLÓGICAS Y VISIONES PEDAGÓGICAS SOBRE LA ENSEÑANZA Y EL APRENDIZAJE DE LAS CIENCIAS: EL CASO DE PROFESORES DE BRASIL Y VENEZUELA
Authors: Camejo Aviles Ivana Elena , Galembeck Eduardo
Published: August 2019

En la actualidad, aún se discute sobre las posibles implicaciones que podrían tener las concepciones epistemológicas y pedagógicas de los profesores de ciencias, sobre la construcción del conocimiento científicos en la escuela. En este estudio se exploran, describen y tentativamente relacionan las concepciones epistemológicas sobre la NdC y las visiones pedagógicas sobre la enseñanza y el aprendizaje de un grupo heterogéneo de profesores, en el intuito de establecer sus posibles aplicaciones o implicaciones de acuerdo con los escenarios y consensos actuales de la alfabetización científica. Del análisis estadístico y de la triangulación metodológica, es posible asegurar que no se reunieron suficientes evidencias para establecer que dichas concepciones influyen en la constitución de visiones pedagógicas sobre enseñanza y aprendizaje.
O ENFOQUE CIÊNCIA, TECNOLOGIA E SOCIEDADE (CTS) NA RECONSTRUÇÃO DA IDENTIDADE PROFISSIONAL DOCENTE
Authors: Moreno Rodríguez Andrei Steveen , Del Pino José Claudio
Published: August 2019

Com o objetivo de compreender as contribuições do enfoque Ciência, Tecnologia e Sociedade (CTS) na reconstrução da identidade profissional docente, apresenta-se a análise de uma experiência de formação docente desenvolvida durante o primeiro semestre de 2016 dentro do marco do Programa Institucional de Bolsas de Iniciação à Docência – PIBID – no subprojeto Química da Universidade Federal do Rio Grande – FURG. Durante seu desenvolvimento foram realizados estudos teóricos e planejamento de atividades na perspectiva CTS. Registros obtidos desse processo (diário de pesquisa, portfolios e entrevistas) foram analisados por meio de Análise Textual Discursiva - ATD, da qual resultaram três categorias finais emergentes, apresentadas neste documento por meio de um metatexto: Repercussões Teórico Práticas do Enfoque CTS na Formação de Professores; Reconstrução da Identidade Profissional Docente; Contexto Sociopolítico e Condições de Trabalho dos Professores. O trabalho realizado, além de trazer aportes teóricos e práticos acerca da abordagem CTS em sala de aula, propiciou a identificação das caraterísticas e pressupostos do enfoque (contextualização, interdisciplinaridade, trabalho coletivo e pensamento crítico) que impulsam a reconstrução da identidade profissional docente e a melhoria dos processos educativos.
Volatile compounds of Macedonian fermented sausage as affected by ripening process using SPME/GC-MS
Authors: Sulejmani Erhan , Demiri Muhamet
Published: August 2019

The profiles of volatile compounds of Macedonian dry fermented sausage were determined by gas chromatography-mass spectrometry (GC?MS) using a solid- -phase microextraction (SPME). A total of 103 volatile compounds were identified and consisted of 12 acids, 16 ketones, 21 terpenes, 20 alcohols, 9 esters, 13 hydrocarbons and 12 miscellaneous. The analysis of the main volatile aromatic components proved that 62% of the compounds that were detected on the first days are terpenes and their content increased to 69 and 80% on days eight and fifteen, respectively. The 50% of the total concentration of volatile components results to be concentrated on the last day (15th) of ripening. They have the highest amounts of concentration of acids (57%), ketones (68%) and terpenes (56%) from the total concentration. There was a significant difference between the various periods of fermentation and there can be differences in the manufacture production stages. Macedonian dry sausages contain high levels of spicy terpenes, which could play an important role in the general flavour notes of this meat product.
Organization of Post-Stroke Rehabilitation Services: Changes between 2013 and 2018 in Services Provided by Health System in Mongolia
Authors: Shirmen Batchimeg , Oidov Batgerel , Tsegmid Narantsetseg , Bayartsogt Batzorig , Erkhembayar Ryenchindorj , Guntev Tsagaankhuu , Avirmed Baljinnyam
Published: August 2019

Objectives: Stroke related disabilities significantly decrease patients’ quality of life and post-stroke rehabilitation service is essential. Therefore, we studied post-stroke rehabilitation services and facilities provided in Mongolia between 2013 and 2018. Methods: A longitudinal study was performed in a total of 47 Mongolian hospitals that provide stroke rehabilitation services. A questionnaire regarding the organizational structure of rehabilitation units, equipment used, human resources, and adherence to recommended guidelines was developed and administered to specialists in these hospitals. Results: We recruited 47 (89%) out of 50 and 47 (94%) out of 53 hospitals delivering stroke rehabilitation service in 2013 and 2018 respectively. 25-34% of these hospitals provided post-stroke rehabilitation, with the majority being incapable of providing multidisciplinary team rehabilitation. The number of physiatrists and physical therapists increased significantly from 2013 to 2018 (p<.001) although the number of physical (p<.002) and occupational therapists (p<.001) was significantly lower in the rural areas. Utilization of Functional independence measures, namely, the Barthel index and modified Rankin scales were increased in 2018 compared to 2013. Conclusion: The majority of post-stroke rehabilitation services are not improved since 2013. Consistent national programs and policies are required to provide adherence to post-stroke rehabilitation guideline recommendations and implementation in clinical practice.
Evaluation of Quality of Life and Treatment Outcome among Stroke Patients with Dysphagia
Authors: Bai Shu Mandula , Gombodorj Ankhbold , Zorigtbaatar Bolortsetseg , Avirmed Baljinnyam , Sonomjamts Munkhbayarlakh
Published: August 2019

Objectives: Dysphagia occurs in 37-78% of stroke patients. We aimed to study the effect of three treatments on the quality of life of stroke patients with dysphagia. Methods: The study was a hospital-based, cross-sectional study. Participants were enrolled from the Affiliated Hospital of Inner Mongolian University for the Nationalities between July 2018 and March 2019. All patients were randomly divided into three treatment groups. One hundred forty-nine patients with post-stroke dysphagia were evaluated by Swallowing-Related Quality of Life (SWL-QOL) Scale before and after the treatment. Results: The mean age of the patients was 59.70 ± 9.55 years, with no difference between treatment groups. There was a statistically significant improvement in scores for all three treatments compared to pretreatment (p=.0001). The SWAL-QOL score was 39.25 ± 3.50 after sensory treatment combined with conventional swallowing therapy, 39.10 ± 3.54 following motor treatment combined with conventional therapy, and 42.12 ± 4.55 in neuromuscular stimulation combined with conventional therapy with latter’s scores significantly higher than the other treatments (p<.01). Conclusions: Conventional therapy combined with neuromuscular electrical simulation provided a better outcome than conventional therapy combined with nerve or muscular stimulation in stroke patients with dysphagia.
Prevalence of Overweight and Obese School-Going Adolescents in Ulaanbaatar and Its Lack of Associated Risk Factors
Authors: Ganbold Oyundari , Erdenebileg Nasantogtokh , Ganbat Mandukhai
Published: August 2019

Objectives: The high prevalence of overweight and obese adolescents has severe consequences for economic and social development in Mongolia. This study aims to describe the prevalence of obesity and its associated factors among adolescents. Methods: Using the published results of the 2013 Global School-based Student Health Survey (GSHS), we determined the prevalence of overweight and obese youth as well as some aspects of their physical activity, alcohol consumption, tobacco usage, and dietary behavior. A total of 5393 students from grade 7-12 students who were normal weight, overweight or obese were studied. Results: Approximately 15% of adolescents were overweight or obese with significant differences in BMI when comparing students in grades 7 to 9 to students in grades 10 to 12 (p= .004). More of the students from grades 7 - 9 were overweight than obese (13.3% vs. 10.7%), while more in grades 10 - 12 were obese (2.1% vs. 1.1%). None of the risk factors available in the GSHS data set were related to being overweight or obese. Conclusion: Using the potential risk factors available in the GSHS data set, none were associated with being overweight or obese. There is a need for better understanding of the social, economic, and physical determinants of the high prevalence of overweight and obese adolescents in Mongolia.
PEMBERDAYAAN MAHASISWA FAKULTAS KESEHATAN MASYARAKAT UNIVERSITAS NUSA CENDANA UNTUK PENGHAPUSAN STIGMA PADA ORANG DENGAN HIV DAN AIDS
Authors: Manurung Imelda F.E.
Published: August 2019

Stigma pada orang dengan Human Immunodeficiency Virus (HIV) dan Acquired Immuno Deficiency Syndrom (AIDS) adalah salah satu faktor penghambat dalam pengendalian penularan penyakit ini. Mahasiswa adalah kaum intelektual yang diharapkan dapat menjadi agen peubah yang potensial dalam kampus dan masyarakat. Namun masih banyak mahasiswa FKM yang masih memberikan stigma pada penyakit HIV dan AIDS. Oleh karena itu kegiatan ini bertujuan untuk memberdayakan mahasiswa FKM untuk terlibat dalam penghapusan stigma pada orang dengan HIV dan AIDS (ODHA). Metode pelaksanaan yaitu dengan pelatihan, kunjungan ODHA dan praktek dikampus. Hasil dari pengabdian terbentuk 2 kelompok mahasiswa yang memiliki kemampuan untuk melakukan kampanye penghampusan stigma terhadap ODHA. Selain itu mahasiswa juga mampu menyusun materi dan melakukan kampanye pengahapusan stigma pada ODHA di kampus. Dari pengabdian ini dapat disimpulkan bahwa mahasiswa FKM dapat diberdayakan untuk kegiatan kampanye HIV dan AIDS. Mahasiswa adalah individu yang potensial sebagai agen peubah bagi remaja milenial dalam pencegahan HIV dan AIDS. Kata kunci: Pemberdayaan, Stigma, HIV dan AIDS.AbstractStigma in people with HIV (Human Immunodeficiency Virus) and Acquired Immuno Deficiency Syndrom (AIDS) is one of the inhibiting factors in controlling the transmission of this disease. Students are intellectuals who are expected to be potential agents of change within the campus and society. However, there are still many FKM students who still stigmatize HIV and AIDS. Therefore this activity aims to empower FKM students to be involved in eliminating the stigma on people living with HIV and AIDS (PLWHA). The method of implementation is by training, visiting PLWHA and practicing in the campus. The results of the service were formed by two groups of students who had the ability to campaign for the elimination of stigma against PLWHA. In addition, students are also able to compile material and conduct campaigns to eliminate stigma on PLWHA on campus. From this service it can be concluded that FKM students can be empowered for HIV and AIDS campaign activities. Students are potential individuals as agents of change for millennial teenagers in the prevention of HIV and AIDS.Keywords:Empowerment, Stigma, HIV and AIDS.
PEMAHAMAN DAN PENYULUHAN MANAJEMEN WAKTU PADA PENGOLAHAN BAHAN PANGAN SEBAGAI RINTISAN AWAL WIRAUSAHA MAKANAN MUDAH SAJI SEHAT HALAL PADA KELOMPOK PENGAJIAN IBU-IBU
Authors: Badriyah Nurul
Published: August 2019

Pelatihan dan pendampingan ini bertujuan untuk meningkatkan pengetahuan perempuan/Ibu-ibu anggota pengajian dalam berwirausaha, meningkatkan ketrampilan perempuan khususnya di dunia kuliner dan packaging produk siap masak dan saji dan membentuk bisnis produk makanan siap masak dan saji skala rumah tangga kecil. Dengan metode kegiatan yang dirancang dalam bentuk pemahaman, pelatihan dan dilanjutkan dengan pendampingan, dan kegiatan ini akan berdampak pada upaya menumbuhkan jiwa wirausaha ibu-ibu rumah tangga, utamanya yang bersumber ide-ide kreatif. Pelatihan ini dilaksanakan pada kelompok pengajian Majlis Taufiqur Rohman, Oro-Oro Dowo yang secara struktural berada di bawah ketakmiran Musholla Taufiqur Rohman dan lingkup kelompok Nahdhatul Ulama Ranting Oro-Oro Dowo Kota Malang, sebagai wilayah yang dituju pada kegiatan pengabdian kepada masyarakat ini. Pendampingan merupakan langkah akhir dari pengabdian masyarakat ini. Tujuan dari adanya pendampingan kegiatan adalah untuk memonitor anggota kelompok pengajian ibu–ibu dalam melaksanakan kegiatan ini agar tetap berlangsung dan apabila terdapat kendala selama kegiatan maka dapat didiskusikan lebih lanjut oleh tim pengabdi untuk menemukan solusi dan memperbaiki progam yang telah berjalan ini. Kata kunci: Wirausaha, Manajemen Waktu, Pemberdayaan Perempuan. Abstract This training and mentoring aim to increase the knowledge of women and/or female members of recitation group in entrepreneurship, improving their skills especially in matters of culinary and cooking ready to eat food product and establishing a smallscale homemade food business. With methods of activities that was designed in the form of comprehension, training, and also mentoring and this activity will have an impact on the effort to foster entrepreneurship spirit of housewives, primarily those that came from creative ideas.This training will be carried out on recitation group of MajlisTaufiqur Rohman, Oro Oro Dowo which is structurally under the administrator of mushola Taufiqur Rohman and within the scope of Nadhatul Ulama branch group of Oro-Oro Dowo of Malang City, as the intended region for this community service, Mentoring is the last step of this community service. The purpose of having a mentoring session is to observe the women member of the recitation group in undertaking this activity without any problems and if there are indeed problems during the duration of the activity, they will be discussed further by the team to find a suitable solution and ensuring the success of the program.  Keywords: Entrepreneur, Time Management, Women Empowerment.
EDUKASI GERAKAN LITERASI SEKOLAH DAN PENANAMAN SIKAP CINTA TANAH AIR DALAM MENGHADAPI ERA DISRUPSI 4.0 PADA ANGGOTA YAYASAN BINA UTAMA MELATI
Authors: Megawati Erna , Megawanti Priarti
Published: August 2019

Kegiatan pengabdian kepada masyarakat ini dilakukan dalam rangka memberikan edukasi dalam mengenai konsep dan contoh penerapan gerakan literasi sekolah dan sikap cinta tanah air bagi anggota Yayasan Bina Utama Melati. Melalui kegiatan ini diharapkan bisa memberikan pemahaman secara teoretis dan aplikatif terhadap gerakan literasi sekolah dan sikap cinta tanah air di lingkungan Yayasan Bina Utama Melati sebagai satu antisipasi menghadapi era disrupsi 4.0 yang tidak dapat dihindari. Model pelaksanaan yang akan dilakukan dalam kegiatan ini berupa ceramah dan diskusi yang menitikberatkan pada konsep dan penerapannya.  Kata kunci: Gerakan Literasi Sekolah, Cinta Tanah Air, Era Disrupsi 4.0 AbstractThis public service activity was conducted in order to give education concerning concept and applications of school literacy movement and nationalism among the members of Yayasan Bina Utama Melati. Through this activity it is expected to give a comprehensive understanding of school literacy movement and nationalism as an anticipation in facing era disruption 4.0 which cannot be avoided. Model of realization this activity was lecturing and discussion which emphasized on concept and its application. Keywords: School Literacy Movement,  Nationalism, Era Disruption 4.0.
PEMBINAAN TATA BAHASA DAN TATA BENTUK SURAT-MENYURAT INDONESIA PADA KELOMPOK BIDANG EKSTRAKURIKULER SMA MUHAMMADIYAH KEDAWUNG KABUPATEN CIREBON
Authors: Pujiatna Tri
Published: August 2019

Kegiatan surat-menyurat memiliki peran penting dalam menyampaikan sebuah informasi. Agar komunikasi berjalan dengan baik, maka isi surat harus jelas kepada pihak penerima surat. Untuk mencapai tujuan itu, maka dibutuhkan tata kelola penulisan surat untuk memudahkan timbal balik surat dalam pembuatan. Surat akan terasa baik apabila bahasa yang digunakan menggunakan bahasa Indonesia yang baik dan benar sesuai dengan pedoman ejaan. Bahasa yang digunakan di dalam kegiatan surat-menyurat harus efektif, wajar, logis, hemat, cermat, sopan, dan menarik. Hal tersebut harus diperhatikan mengingat ruang tulis dalam surat terbatas. Tata bentuk surat tidak kalah pentingnya. Dalam kegiatan surat-menyurat Indonesia mengenal beberapa bentuk surat berdasarkan tata bentuknya, di antaranya: bentuk lurus penuh, bentuk lurus, bentuk setengah lurus, bentuk bertakuk, bentuk Indonesia lama, bentuk Indonesia baru, bentuk menggantung.  Oleh karena itu, perlu adanya pembinaan terhadap tata kelola surat-menyurat Indonesia. Melalui teknik pendampingan,tanya jawab serta latihan,  pengabdian ini menghasilkan suatu pemahaman pada proses penyusunan serta penulisan surat yang sesuai dengan  kaidah  bentuk  dan tata bahasa surat-menyurat pada kelompok bidang ekstrakurikuler SMA Muhammadiyah Kedawung Kabupaten Cirebon. Kata Kunci: Surat Bahasa Indonesia; Surat-menyurat Indonesia; Tata Bahasa Surat Indonesia; Tata Bentuk Surat Indonesia. Abstract Mailing activities have an important role in conveying information. In order for communication to run well, the contents of the letter must be clear to the recipient of the letter. To achieve this goal, the management of permits is needed to facilitate reciprocity of letters in the making. The letter will feel good translated using good and correct Indonesian in accordance with spelling instructions. The language used in correspondence activities must be effective, reasonable, logical, thrifty, careful, polite, and interesting. This must be noted in the limited space for writing space. The form of letters is no less important. In Indonesian correspondence activities recognize several forms of letters according to their form, here: full straight forms, straight forms, straight forms, curved forms, old Indonesian forms, new Indonesian forms, Indonesian forms. Therefore, there is a need for guidance on Indonesian correspondence governance. Through mentoring, question and answer and practice techniques, this service produces an understanding of the manufacturing process as well as renewing letters in accordance with the rules of letter-form and grammar in the extracurricular field group of Muhammadiyah Kedawung High School, Districts Cirebon. Keywords: Indonesian Letter; Indonesian correspondence; Indonesian Letters of Grammar; Forms of Indonesian Letters
The Figurative Aspect of Rock Hero’s Loneliness
Authors: Doronin Vladimir Viktorovich ,   Tyumen State University
Published: August 2019

The study discusses the figure of a rock hero as a subject of rock culture. This figure is complex and multi-valued and synthesizes various qualities and properties. To realize his potential, the rock hero must overcome both external physical and internal existential obstacles and challenges. One such challenge is loneliness. In view of the special value system, worldview, and behavior of the rock hero, loneliness appears in different contexts. The study considers its figurative aspect, i.e. the main markers and manifestations of loneliness in rock culture. From the standpoint of philosophy, namely aesthet-ic anthropology, it has become a problem to overcome loneliness through the aesthetic power of creativity rooted in rock culture and embodied by the rock hero despite its peculiar form.
The Evolution of Chinese Greeting Etiquette before the Xinhai Revolution
Authors: Wang Dan ,   Far Eastern Federal University
Published: August 2019

The culture of rituals and customs is an integral part of traditional Chinese culture. The ritual acts as a standardized norm and helps formalize everyday communication of people in China. The study fo-cuses on the evolution of Chinese greeting etiquette before the Xinhai Revolution during the domination of Confucianism. Different forms of etiquette have been studied, depending on their emergence in China. The author conducts a comparative analysis of various Chinese greetings such as kneel-ing and hand gestures. The research elaborates on nine forms of kneeling. Kneeling played a big role in strengthening the feudal hierarchy; therefore, Chi-nese society paid much attention to it com-pared to hand greetings. However, when the Repub-lic of China was founded in 1912, the ritual of kneeling greeting was replaced by standing. Greeting people by folded hands (standing) is still relevant today. It is a widespread everyday practice in Chinese society and an important part of Chinese traditional culture.
Cultural Heritage Paradigms and Ethnographic Collections of V.K. Arsenyev: Museum Practices
Authors:   Arsenyev State United Museum of Primorsky Region, Kavetskaya Vera Vyacheslavovna
Published: August 2019

Cultural heritage has become a key concept in the field of culture and a resource for territories’ devel-opment. A series of cultural turns experienced by mankind have mostly led to changes in attitudes towards it. In the 20th century, there were three main paradigms related to heritage conservation activi-ties: attitude to heritage as a monument, as a re-source and product, and as a factor determining the quality of life of human and society. The rapid evolution of the concept of heritage has resulted in a broad reflection of the inheritance process. It is of particular importance to the ethnocultural heritage of the indigenous peoples of the Far East since their traditional culture lacks systems and needs the heritage preserved by muse-ums. The ethnographic museum collections acquired by foreign cultural researchers in the late 19th – early 20th centuries serve as an important transmitter of cultural traditions and should be rein-terpreted. The activities of V.K. Arsenyev are regard-ed as an institutional creation of the ethnocultural heritage of several Far Eastern regions. He was a traveler and writer who made an invaluable con-tribution to the preservation of the one-of-the-kind culture of the Udege people. The study describes the museum practice of updating and dealing with the ethnographic heritage of V.K. Arsenyev.
Penandaan Alfa-Mangostin dengan Radionuklida Teknesium-99m sebagai Senyawa Deteksi Kanker
Authors: Setyawati Luthfi Utami , Islamiaty Risda Rahmi , Reinard Lie Kevin , Wijaya Cindy Aprillianie , Muchtaridi Muchtaridi
Published: August 2019

α-mangostin merupakan turunan xanthon yang banyak terdapat pada kulit dan buah manggis.     α-mangostin memiliki kemampuan menekan pembentukan senyawa karsinogen yang merupakan salah satu penyebab terjadinya kanker. α-mangostin dapat membentuk kompleks khelat dengan logam seperti teknesium-99m (99mTc), sehingga dapat membentuk sediaan radiofarmaka yang dapat digunakan sebagai diagnosis kanker. Penelitian ini bertujuan untuk mendapatkan sediaan radiofarmasi 99mTc-Alfamangostin dengan metode langsung dengan melakukan optimalisasi terhadap beberapa parameter seperti jumlah reduktor, kondisi pH, jumlah ligan, dan waktu inkubasi. Penentuan kemurnian radiokimia dilakukan dengan kromatografi lapis tipis dengan pengembang  campuran amonia : etanol : air dengan perbandingan 1 : 2 : 5 untuk memisahkan pengotor radiokimia berupa TcO2 dan NaCl 0,9% untuk  memisahkan pengotor radiokimia berupa TcO4. Kondisi optimum penandaan diperoleh pada pH 9, dengan jumlah reduktor 50 μl, jumlah ligan α-mangostin 1000 μg dengan waktu penandaan pada menit ke 0 pada suhu kamar (250C) dengan kemurnian radiokimia 86.5 ± 1,31 %. Kata kunci : Kanker, α-mangostin, Teknesium-99m, Radiofarmaka
Religious Disagreement, Religious Experience, and the Evil God Hypothesis
Authors: Lougheed Kirk
Published: August 2019

Conciliationism is the view that says when an agent who believes P becomes aware of an epistemic peer who believes not-P, that she encounters a (partial) defeater for her belief that P. Strong versions of conciliationism pose a sceptical threat to many, if not most, religious beliefs since religion is rife with peer disagreement. Elsewhere (Removed) I argue that one way for a religious believer to avoid sceptical challenges posed by strong conciliationism is by appealing to the evidential import of religious experience. Not only can religious experience be used to establish a relevant evidential asymmetry between disagreeing parties, but reliable reports of such experiences also start to put pressure on the religious sceptic to conciliate toward her religious opponent. Recently, however, Asha Lancaster-Thomas poses a highly innovative challenge to the evidential import of religious experience. Namely, she argues that an evil God is just as likely to explain negative religious experiences as a good God is able to explain positive religious experiences. In light of this, religious believers need to explain why a good God exists instead of an evil God. I respond to Lancaster-Thomas by suggesting that, at least within the context of religious experience, (i) that the evil God hypothesis is only a challenge to certain versions of theism; and (ii) that the existence of an evil God and good God are compossible.
Increased expression of pentraxin 3 in placental tissues from patients with unexplained recurrent pregnancy loss
Authors: Zeybek S , Tepeli E , Cetin GO , Caner V , Senol H , Yildirim B , Bagci G
Published: August 2019

Pentraxin 3 (PTX3), a prototypical member of the long pentraxin subfamily, is a evolutionarily conserved multimeric pattern recognition receptor involved in the humoral component of the innate immune system. Pentraxin 3 is released when tissue is stressed or damaged, and interacts with many different ligands. Pentraxin 3 exerts a pivotal role both as a regulator and as an indicator of inflammatory response in the pathogenesis of many diseases such as sepsis, vasculitis and preeclampsia. Uncontrolled inflammatory response is considered a major cause of unexplained recurrent pregnancy loss (URPL). We determined the PTX3 messenger ribonucleic acid (mRNA) and protein expression levels in placentai tissues from 50 women with URPL, and made comparison with those in 50 age-matched control subjects. In quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry analyses, PTX3 mRNA and protein levels, respectively, were significantly increased in URPL patients compared with their respective controls (p = 0.0001). Although no significant correlations were identified between PTX3 expression levels and clinical parameters such as maternal age, numbers of previous pregnancy losses, and gestational age at miscarriage, PTX3 mRNA expression was significantly higher in patients with no live births than in women with previous live births (p = 0.0001). Our study suggests that tissue-specific expression of PTX3 is associated with URPL. Further larger studies are required to determine whether PTX3 expression can be used as a biomarker to manage URPL in routine clinical practice.
Prenatal diagnosis of organic acidemias at a tertiary center
Authors: Tanacan A , Gurbuz BB , Aydin E , Erden M , Coskun T , Beksac MS
Published: August 2019

The aim of this study was to share our experience in the prenatal diagnosis (PND) of organic acidemias (OAs) in our clinic. This study consisted of 10 cases in whom an invasive prenatal diagnostic test (IPNDT) was performed by a single physician for the PND of OAs. Median maternal age, parity, gestational week of IPNDT, prenatal test indications, OA types, method of IPNDT, IPNDT results and gestational outcomes were evaluated. Targeted mutation analysis was performed in fetal DNA for the specific mutations by using polymerase chain reaction (PCR) and direct Sanger sequencing. The diagnosis was confirmed by genetic targeted mutation analysis after birth. Median maternal age, parity and gestational week of IPNDT values were 30 (range 21-35), one (range 0-4) and 11.5 (range 11-17), respectively. Indications for IPNDT were mother being a carrier of the disease for one case (10.0%) and at least one child with OA in the family for nine cases (90.0%). Organic acidemia types investigated were maple syrup urine disease (MSUD), methylmalonic acidemia (MMA) and isovaleric acidemia (IVA) in five (50.0%), three (30.0%) and two (20.0%) patients, respectively. Chorion villus sampling (CVS) was done in seven (70.0%) patients and amniocentesis was performed in three (30.0%) patients. Eight fetuses (80.0%) were found to be healthy and two fetuses (20.0%) were found to be affected (one case with IVA and one case with MMA). The two pregnancies (20.0%) with affected fetuses were terminated. Prenatal diagnosis of OAs is critical. Appropriate prenatal counseling should be given to families with known risk factors.
Novel patterns of the Epstein-Barr nuclear antigen (EBNA-1) V-Val subtype in EBV-associated nasopharyngeal carcinoma from Vietnam
Authors: Thuan LD , Kha ND , Minh NT , Thuy LHA
Published: August 2019

The Epstein-Barr nuclear antigen 1 (EBNA-1) gene, plays a key role in viral infection, immortalization, viral genome replication, transcription and maintenance, and is the frequently detected gene, protein in both latent and lytic stage of Epstein-Barr virus (EBV). Based on the amino acid at position 487, EBNA-1 was classified into five subtypes, including P-Ala, P-Thr, V-Val, V-Pro and V-Leu. In Vietnam, an Asian country with a high incidence, mortality rates of nasopharyngeal carcinoma (NPC), had limited research on the EBNA-1 variation. Therefore, the aim of the current study was to identify the pattern of the EBNA-1 V-Val subtype in Vietnamese NPC patients, for its value further applied in NPC patients. Fifty-eight NPC biopsy samples were collected from local patients, analyzed by nested-polymerase chain reaction (nested-PCR), sequencing and compared to a previous B95-8 prototype sequence. Four EBNA-1 subtypes, including V-Val (35/44, 79.55%), P-Ala (2/44, 4.55%), P-Thr (5/44, 11.36%), and V-Leu (2/44, 4.55%), were observed in 44/58 samples. The sequences of the V-Val subtype were compared to the B95-8 prototype, resulting in five patterns, contained seven consensus changes, including five amino acid changes at positions 487, 499, 502, 524, 594, and two silent changes at residues 520 and 553. Of these, four of five, patterns were identified as novel patterns of the V-Val subtype, showing the different changes of amino acids at positions 492, 528, 529, 553, 585 and 588, by comparison with previous studies of V-Val EBNA-1. Those data suggested the profile of variation patterns of the EBNA-1 gene, related to geographic distribution, in Vietnamese NPC patients.
A systematic clinical review of prenatally diagnosed tetrasomy 9p
Authors: Vinkšel M , Volk M , Peterlin B , Lovrecic L
Published: August 2019

Tetrasomy 9p was first described in 1973 and approximately 68 cases with a variable phenotype have been reported to date with 22 of them being detected prenatally. The objective of this study was to review prenatally-reported cases of tetrasomy 9p thus far and to identify ultrasound phenotypes that may be suggestive of this specific syndrome. A PubMed database search was done in February 2018 without any restriction of publication date orjournals, with the use of the following keywords: tetrasomy 9p, tetrasomy 9p prenatal, mosaic tetrasomy 9p, mosaic tetrasomy 9p prenatal, isochromosome 9p, duplication 9p prenatal, trisomy 9p prenatal. Reported cases were included if the clinical presentation and diagnostic approach of each case was clearly described. The most common characteristics of prenatally-detected tetrasomy 9p are intrauterine growth retardation (IUGR, 57.0%), central nervous system (CNS) abnormalities (59.0%), skeletal anomalies (29.0%), genitourinary and renal anomalies (29.0%) and cardiac defects (29.0%). The phenotypic spectrum of tetrasomy 9p is rather unspecific as these findings are commonly associated with other chromosome anomalies, as well as microdeletion/microduplication or monogenic syndromes. The combination of early fetal morphology and diagnostic genetic testing enables a definite tetrasomy 9p diagnosis and effective further pregnancy management.
Comparative expression analysis of human endogenous retrovirus elements in peripheral blood of children with specific language impairment
Authors: Minchev DS , Popov NT , Naimov SI , Minkov IN , Vachev TI
Published: August 2019

Specific language impairment (SLI) is a psychiatric condition with a complex etiology and a substantial genetic basis that affects children's verbal communication abilities. In this study, we examined the expression of five different human endogenous retrovirus elements (HERVs) in a cohort of 25 children with SLI and 25 healthy children in the control group. Human endogenous retrovirus elements, a diverse group of repetitive DNA sequences, can potentially cause considerable genetic heterogeneity. They had been integrated in the genome of our ancestors throughout evolution and now consist of about 8.0% of the human genome. Several HERV loci are transcribed in various cell types. Their expression in peripheral blood and in the brain is altered in many neurological and psychiatric diseases. To date, HERV expression profiles have never been studied in patients with SLI. This study aimed to elucidate differentially regulated human endogenous retroelements in peripheral blood of children with SLI, in comparison with healthy controls, through quantitative reverse tran-scription-polymerase chain reaction (qRT-PCR) methodology. Our results show that two genes: HERV-K (HLM-2) gag and HERV-P env were expressed at lower levels in the blood samples from SLI children in comparison with those in the control group.
Structural, morphological, optical and diode properties of chemical bath deposited nano-structured CdS thin films using EDTA as a complexing agent
Authors: Vidhya S.N. , Karunakaran R.T.
Published: August 2019

CdS thin films with (1 1 1) orientation were prepared by chemical bath deposition technique at 80±5 °C using the reaction between NH4OH, CdCl2 and CS(NH2)2. The influence of annealing temperature varying from 150 °C to 250 °C was studied. X-ray diffraction studies revealed that the films are polycrystalline in nature with cubic structure. Various parameters, such as dislocation density, stress and strain, were also evaluated. SEM analysis indicated uniformly distributed nano-structured spherically shaped grains and net like morphology. Optical transmittance study showed the wide transmittance band and absence of absorption in the entire visible region. I-V characterization of p-Si/n-CdS diode and photoluminescence studies were also carried out for the CdS films.
Rynek mangi w Polsce – oferta wydawnicza w latach 1996−2015
Authors: Maciakiewicz Katarzyna
Published: August 2019

The intention of the article is to discuss the evolution of Japanese comics in Poland since 1996, when it appears in the publishing offer, until 2015. It presents the beginning of the creation of the manga and briefly characterizes all its transformations. The article focuses on the characteristics of this comic, emphasizing its differences from similar texts. The basic consideration is the publishing offer available in Poland, which consists of the number of publishing houses specializing in publishing Japanese comic books and the number of titles published by them. The whole text shows the analysis of statistical data, indicating the interest in manga among Polish customers.
Typografia to uderzenie, forma, kształt, konstrukcja Szczuka, Strzemiński, Berlewi, Hiller, czyli polska awangarda artystyczna w projektowaniu graficznym druków pierwszej połowy XX wieku w Polsce
Authors: Ladurucki Jacek
Published: August 2019

The aim of the article is to analyse the selected examples of avant-garde books and to present the means of graphical expression in the design concepts of the most important creators of the Polish graphics art if the 20th century. It is also important to point out the element of the cultural interpretation of the phenomena from the borderline of arts, literature and artistic performance connected with the context of time, space and breaking the social barriers. The art of avant-garde has presented a book as an object of social use and anthropologically adapted to a man. Artists such as Mieczysław Szczuka, Teresa Żarnowerówna, Henryk Berlewi, Władysław Strzemiński, Karol Hiller had in an original way composed the space of artistic communicates, the internal space of literature and dynamized the canons of typography.
Twórczość Olgi Tokarczuk na serbskim i chorwackim rynku książki
Authors: Luković Dagmara
Published: August 2019

Olga Tokarczuk is currently the most known and most translated Polish writer in Serbia and Croatia. Despite the linguistic closeness of the two languages the book markets, including the foreign literature translations, are growing separately, although it cannot be said that without and mutual influence. The reception of the creative output of the author of “Flights” is facilitated by a hefty financial backing from Poland. Croatian translators are more eager to work on shorter literary forms (essays, short stories), while in Serbia the interest sways more to the side of novels, and essays and short stories are usually considered trailers for bigger publications (e.g. collections of essays). Media in Serbia is much more interested in presenting the creative output of Olga Tokarczuk than it is in Croatia. The forms of promotion and activity in this regard are also much more intense in Serbia than in Croatia, which is in part due to Milica Markić - a Serbian translator of Polish literature.
Planetary Grand Challenges: A Call for Interdisciplinary Partnerships
Authors: Gilbertson Marie L.J. , Craft Meggan E. , Potter Teddie M.
Published: August 2019

Universities have traditionally been places where individual scholars work on individual topics, in individual disciplines, with individual funding. Even though large research institutions include all the major disciplines, faculty and students remain in their schools or colleges, rarely crossing the campus to interact. Matters do not improve once knowledge is generated. Each discipline has its own journals, its own conferences, and its own professional organizations. The academy was designed to support unparalleled expertise in specialized knowledge. However, universities are beginning to realize that the greatest challenges we face are systems problems and can only be solved by systems thinking and systems solutions. Climate change, antibiotic resistance, water scarcity, and unsustainable population growth are just a few of the planetary health crises that require interdisciplinary partnerships to solve. Fortunately, we are beginning to see early signs of a shift toward, and even normalization of, interdisciplinary collaboration. In fact, some national grants require team members from different fields as a stipulation for funding. Interdisciplinary research permits cross-field benefits in which the synergy of two or more knowledge sets is greater than the sum of its parts. Innovation increases and previously elusive solutions become possible. The field of partnership studies closely aligns with the vision and mission of interdisciplinarity and offers a philosophical framework to guide teaching and research.
Where is the Care in Caring: A Polemic on Medicalisation of Health and Humanitarianism
Authors: Lindekens Jordan , Jayawickrama Janaka
Published: August 2019

Currently in the caring professions, the human condition of facing uncertainty and danger is often overlooked in the quest for measurable outcomes that prove efficiency, taking agency out of the hands of the individuals being cared for. Traits that make an ‘ideal’ practitioner include compassion, advocacy skills, and the ability to engage with people in vulnerable situations, and to establish trusting, respectful relationships. Within a system of models, quotas, and specialties, these traits are easily hindered within health care and humanitarianism. The critical examination in this article in no way rejects the valuable elements in the fields of humanitarianism and health care. Rather, it discusses how care can be re-introduced. Uncertainty and danger are part of the human experience, and caring interventions need to take that into account. This article highlights the benefits of a collaborative relationship between the person in crisis and the practitioner, instead of a paternalistic relationship in which the practitioner is viewed as the ‘expert.’ With a caring perspective, the individual who is experiencing the crisis will retain ownership of and responsibility for their life, and not rely solely on external sources of wellbeing and comfort.
INSTITUIÇÕES QUE INFLUENCIARAM NA PRODUÇÃO DE CAFÉ DE QUALIDADE NA COLÔMBIA: UMA ANÁLISE HISTÓRICO-COMPARADA
Authors: Ortega Lizeth Cristina Chatez , Brisola Marlon Vinícius
Published: August 2019

O estudo realiza uma análise histórico-comparada da evolução institucional das dimensões tecnológica, comercial e organizacional do Sistema Agroindustrial (SAG) do café na Colômbia no período compreendido entre 1990 e 2016. O período de tempo se refere àquele em que as condições do comércio internacional do café foram configuradas para uma nova estrutura de demanda e oferta, que gerou mudanças nas tradicionais práticas produtivas e comerciais. A evolução institucional é posta na forma de ‘casos’, em períodos com intervalos de três anos. O procedimento metodológico, pouco explorado em estudos acadêmicos na América Latina, utilizou uma tabela de análise comparativa fazendo uso de ferramentas próprias da técnica QCA (Qualitative Comparative Analisys). Os achados revelaram que as instituições correspondentes ao componente tecnológico tiveram sua maior importância nessa evolução e na competitividade do produto e que a construção institucional concebida a partir da coordenação do SAG, por meio da implantação de uma estratégia de diferenciação baseada na qualidade, gerou impacto de forma positiva na eficiência e competitividade deste SAG.
GERAÇÃO DE VALOR ECONÔMICO NA AGRICULTURA FAMILIAR: DIFERENTES RETRATOS DO PRODUTOR RURAL BRASILEIRO
Authors: Silva Rodrigo Peixoto da , Castro Nicole Rennó , Pereira Franciele de Oliveira
Published: August 2019

Existem diversos debates acerca da definição de agricultura familiar (AF) motivados pela amplitude dos perfis de estabelecimentos englobados pela lei. A questão ganha relevância uma vez que a definição foi criada para dar suporte à implementação de políticas para o desenvolvimento econômico de agricultores desfavorecidos e pelo fato de que, segundo Buainain et al. (2013), em nenhum outro momento da história os pequenos estabelecimentos estiveram tão próximos da marginalização. Esse trabalho buscou contribuir com a compreensão acerca da heterogeneidade na capacidade de geração de valor entre os estabelecimentos de AF, utilizando uma análise de clusters via Model-Based-Clusters. Entre os principais resultados tem-se que a maior parte dos clusters foi formada por municípios com rentabilidades de AF bastante baixas e que, ainda que exista um padrão geográfico na distribuição dos clusters, existem estabelecimentos em situações muito desfavoráveis em todo o território. Diante de tal heterogeneidade, evidencia-se a necessidade de maior detalhamento do conceito e definição legal da agricultura familiar no Brasil para otimizar a formulação e execução de políticas públicas voltadas ao segmento.
AVALIAÇÃO DA SITUAÇÃO NUTRICIONAL NO BRASIL: EFEITOS REGIONAIS E DA RENDA
Authors: Aguiar Danilo Rolim Dias de , Costa Gabriella Nunes da
Published: August 2019

Este artigo examina o acesso alimentar em cada uma das 26 capitais estduais do Brasil e no Distrito Federal por meio de dados de pesquisa de orçamentos familiares. Os resultados mostram que as dietas são bastante diferentes de acordo com a região e a renda e que a deficiência de calorias é muito mais comum do que a deficiência de proteína. A quantidade média de proteína disponível por pessoa está acima dos requerimentos em quase todas as cidades e para indivíduos de todos os estratos de renda, enquanto que para calorias os requerimentos só são cumpridos para os indivíduos que recebem renda per capita acima de três salários-mínimos mensais. A desnutrição se torna mais evidente quando se examina a proporção de famílias sem acesso adequado a proteína e (acima de tudo) calorias. Como as diferenças no acesso alimentar são principalmente, embora não exclusivamente, devido à distribuição de renda, políticas que visem transferir renda ou reduzir o preço dos alimentos aos pobres ajudariam a combater a desnutrição no país.
Listado de las últimas tesis de grado presentadas al Departamento de Historia
Authors: Espacio Historia y
Published: August 2019

Listado de últimas tesis de grado
El Zurriago: cucarrones y coclíes, 1848 – 1854
Authors: Pacheco G. Margarita Rosa
Published: August 2019

Artículo de investigación relacionado con la historia política, enmarcado en una revuelta popular que se dio en Cali durante un periodo del siglo XIX
Los proyectos económicos de los regeneradores en el Valle del Cauca (1875 – 1890)
Authors: Valencia Llano Alonso
Published: August 2019

Documento de investigación relacionado al ámbito de la historia económica en la provincia del Cauca, entre los años de 1863 y 1890