bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Digital Measurement–Based Care for the Treatment of Anxiety and Depression in Children and Adolescents: Observational Retrospective Analysis of Bend Health Data (Preprint)
Authors: Huffman Landry Goodgame , Lawrence-Sidebottom Darian , Huberty Jennifer , Roots Monika , Roots Kurt , Parikh Amit , Guerra Rachael , Weiser Jaclyn
Published: February 2023

BACKGROUND

A growing body of evidence supports the efficacy of measurement-based care (MBC) for children and adolescents experiencing mental health concerns, particularly anxiety and depression. In recent years, MBC has increasingly transitioned to web-based spaces in the form of digital mental health interventions (DMHIs), which render high-quality mental health care more accessible nationwide. Although extant research is promising, the emergence of MBC DMHIs means that much is unknown regarding their effectiveness as a treatment for anxiety and depression, particularly among children and adolescents.

OBJECTIVE

This study uses preliminary data from children and adolescents participating in an MBC DMHI administered by Bend Health Inc, a mental health care provider that uses a collaborative care model to assess changes in anxiety and depressive symptoms during participation in the MBC DMHI.

METHODS

Caregivers of children and adolescents participating in Bend Health Inc for anxiety or depressive symptoms reported measures of their children’s symptoms every 30 days throughout the duration of participation in Bend Health Inc. Data from 114 children (age 6-12 years) and adolescents (age 13-17 years) were used for the analyses (anxiety symptom group: n=98, depressive symptom group: n=61).

RESULTS

Among children and adolescents participating in care with Bend Health Inc, 73% (72/98) exhibited improvements in anxiety symptoms and 73% (44/61) exhibited improvement in depressive symptoms, as indicated by either a decrease in symptom severity or screening out of completing the complete assessment. Among those with complete assessment data, group-level anxiety symptom T-scores exhibited a moderate decrease of 4.69 points (P=.002) from the first to the last assessment. However, members’ depressive symptom T-scores remained largely stable throughout their involvement.

CONCLUSIONS

As increasing numbers of young people and families seek DMHIs over traditional mental health treatments due to their accessibility and affordability, this study offers promising early evidence that youth anxiety symptoms decrease during involvement in an MBC DMHI such as Bend Health Inc. However, further analyses with enhanced longitudinal symptom measures are necessary to determine whether depressive symptoms show similar improvements among those involved in Bend Health Inc.
MINERAL DENSITY AND PROCESSES OF BONE TISSUE REMODELING IN CHILD POPULATION LIVING IN IODINE-DEFICIENT BIOGEOCHEMICAL TERRITORY
Authors:   Federal State-Funded Educational Institution of Higher Education “Bashkir State Medical University” of Ministry of Health of Russia, Kamilov Feliks H. , Ganeev Timur I. ,   Federal State-Funded Educational Institution of Higher Education “Bashkir State Medical University” of Ministry of Health of Russia, Кozlov Valery N. ,   Bashkir Institute of Technologies and Management (branch) Federal State-Funded Educational Institution of Higher Education K. G. Razumovsky Moscow State University of Technologies and Management (FCU), Junusov Renat R. ,   Bashkir State Medical University of Ministry of Health of Russia, Men’shikova Irina A. ,   Bashkir State Medical University of Ministry of Health of Russia, Kryachko Alexey N. ,   Bashkir Institute of Technologies and Management (branch) Federal State-Funded Educational Institution of Higher Education “K. G. Razumovsky Moscow State University of Technologies and Management (FCU)”
Published: January 2023

The territory of the Republic of Bashkortostan belongs to the regions with natural iodine deficiency in soil and water. The population of the republic is at risk of developing iodine deficiency conditions. The aim of the study was to evaluate the frequency of a decrease in bone mineral density and the level of markers of osteoresorption and bone formation in young schoolchildren and adolescents living in a region with natural iodine deficiency. Materials and methods. The survey covered 288 students of general education schools aged 11–12 and 309 students aged 14–15. Theauthors studiedconcentration of iodine in urine, plasma levels of thyroid hormones (thyroid stimulating hormone, free thyroxine), levels of calcium, magnesium, phosphorus, C-terminal telopeptides of type I collagen, activity of the bone isoenzyme of alkaline phosphatase. The volume of the thyroid gland, the mineral density of the bone tissue of the middle diaphysis of the tibia, the lower third of the radius were determined by ultrasonometry. Results and discussion. It was found that children have a high prevalence of iodine deficiency from 44% to 57.6% and a decrease in the concentration of iodine in the urine, an increase in the content of thyrotropin, calcium and magnesium in the blood plasma. Insufficient iodine supply leads to a slowdown in the intensity and imbalance of remodeling with a decrease in bone formation processes.
ASSESSMENT OF THE EFFECTIVENESS OF MANAGEMENT OF THE ACTIVITIES OF A MEDICAL ORGANIZATION TO REDUCE MORTALITY FROM DISEASES OF THE CIRCULATORY SYSTEM BASED ON THE ANALYSIS OF DATA ON THE ACTIVITIES OF MEDICAL ORGANIZATIONS OF THE SVERDLOVSK REGION FOR THE PERIOD 2018-2020
Authors:   Ural Institute of Healthcare Management named after A.B. Blokhin, Ivina Victoria Yu. , Karmatskikh Olga G. ,   Ural Institute of Healthcare Management named after A.B. Blokhin, Anufrieva Elena V. ,   Ural Institute of Healthcare Management named after A.B. Blokhin
Published: January 2023

The purpose. It is advisable to assess the effectiveness of the activities of a large number of medical organizations with varying degrees of achievement of target indicators by ranking by the totality of achieving several indicators based on a multivariate analysis. Materials and methods. The regulatory legal acts of the Russian Federation and the Sverdlovsk region regulating the provision of medical care to patients with cardiovascular diseases were studied. The data of official forms of statistical observation and information on medical care provided to insured citizens of the Sverdlovsk region within the framework of compulsory medical insurance are analyzed. In the process of working with information, a calculation methodology was developed and for the first time applied to form a rating of medical organizations that provide medical care in the profile of cardiology in outpatient and inpatient settings, taking into account the magnitude of deviations from the target values for five groups of indicators, using the principles of the point ranking method. Outcomes. In the course of the work, a list of key indicators for assessing the effectiveness and efficiency of medical organizations in the profile of cardiology was determined, the relationships between these indicators were established, ratings of medical organizations were formed according to the degree of achievement of target indicators in the chosen direction. As a result of the ranking, lists of medical organizations of the Sverdlovsk region have been identified, which may be subject to further thematic audit and in-depth study of both positive and negative of their experience in organizing processes in this area. Conclusion. Assessments of the effectiveness of the activities of a large number of medical organizations with varying degrees of achievement of target indicators are carried out by ranking by the totality of achieving several indicators based on a multivariate analysis.
SELECTED ISSUES OF ADDITIONAL PROFESSIONAL EDUCATION OF MEDICAL WORKERS ON THE BASIS OF THE BLOKHIN INSTITUTE OF HEALTH MANAGEMENT
Authors:   Ural Institute of Health Management named after A. B. Blokhin, Stepanova Lyubov N. , Leontiev Sergey L. ,   Ural Institute of Health Management named after A. B. Blokhin, Mikhailova Diana O. ,   Ural Institute of Health Management named after A. B. Blokhin, Anufrieva Elena V. ,   Ural Institute of Health Management named after A. B. Blokhin
Published: January 2023

Successful implementation of the state program «Health Development» requires a high level of competence in the strategic development of medical organizations and the healthcare industry from managerial personnel. In the current practice in the healthcare system, a person with experience in medical work is often appointed to the position of head, and he has to acquire managerial knowledge and skills directly in the process of activity. The goal of training managerial personnel in healthcare is to master uniform standard professional competencies, which should become the basis of educational programs for additional professional education in all educational organizations. Target. Analysis of the educational activities of the GAUDPO “Institute of Health Management named after A.I. A.B. Blokhin» for the implementation of additional professional education in the field of healthcare. Materials and methods. The study used regulatory legal documents that regulate the issues of training and continuous development of managerial personnel in the healthcare sector, methods of systemic and logical analysis. Analyzed, grouped and statistically processed the results of a survey of students of additional professional education programs in the specialty «Health Organization and Public Health» (255 questionnaires). Results. The actual practice of the activities of medical organizations requires the improvement of approaches to the training of healthcare organizers. The Institute is actively working to develop relevant programs for additional professional education and filling the labor market of the Sverdlovsk region with professional personnel in the field of healthcare. Conclusion. An analysis of the implementation of additional professional education programs by the Institute showed that against the background of mandatory professional retraining programs of 500 hours or more, short-term programs are gaining popularity, allowing them to acquire and “hone” relevant knowledge, skills and abilities. All the main trends of modern additional professional education are implemented by the Institute, taking into account the requests of the main participants in the educational process and the requirements of the health management body — the Ministry of Health of the Sverdlovsk Region.
Factors Affecting Palestinian High School Students’ Career Choice after Covid-19 Pandemic Outbreak
Authors: Egbaria Hamza A.
Published: February 2023

The COVID-19 pandemic outbreak has created a new complicated reality and brought diverse challenges to education systems and students as well. The present study aimed at examining the factors that students have used in identifying career choices among Palestinian high school in Israel in the new era. Career choice questionnaire was used to assess the factors affecting career choice. 455 Palestinian high school students took part in this study. A convenient sampling technique was implied to collect the data. Descriptive statistics, t-test, one-way ANOVA were used to analyze the data. Findings revealed that the student’s interests and hobbies, and student’s personality and tendencies attained the highest value among the internal factors of career choice. Furthermore, the future progress and advancement opportunities, job security were the prominent external factors. Findings showed that the internal factors were significantly associated with economic situation. The findings will assist school counselors to raise the self-awareness to the importance of the internal and external factors, thus students may make better future career decisions.
Production Growth Response of Two Sugar Cane Varieties (Saccharum officinarum L.) At Available Various Water Levels
Authors: Maulana Zulkifli , Muhibuddn Andi , Boling Jeferson , Amiruddin Amiruddin , Hamsina Hamsina , Rachmawati Rachmawati , Hasani Ruslan
Published: February 2023

This study on available water content aims to determine the ability of sugarcane plants to grow and produce under water-stressed conditions. This research is expected to be used as one of the references in making decisions to use water efficiently in the Takalar sugar factory's sugarcane plantations. The study used two varieties of sugar cane namely PS. 61 and Q 81. The two varieties were planted at various moisture content levels, namely 25-50%, 50-75%, and 75-100%. The results showed that having 50-75% available water content had a better effect on sugarcane growth during the dry months of September and October. The Q 81 variety is better able to utilize the limited water supply for growth and production. The amount of available water and the variety of growth and sugarcane production have a significant interaction.
Agricultural Development Asymmetries in Contemporary Kalmykia: Results and Prospects
Authors:   Kalmyk Scientific Center of the RAS, Namrueva Ludlmila
Published: January 2023

Introduction. Agriculture is a priority sector of Kalmykia’s economy. Both the economic and social spheres of the Republic depend on its actual conditions. Goals. The study aims to identify the dynamics and factors of change for asymmetries in the agricultural sector of present-day Kalmykia. Materials. To facilitate this, the paper analyzes statistical data characterizing modern socioeconomic processes in the Republic, reviews scientific publications examining the current state of the region’s economy. Results. The key factors of Kalmykia’s socioeconomic development asymmetries are the poorly diversified economic structure characterized by a pronounced agricultural orientation, deterioration of sociodemographic indicators (population decline, low wages and incomes, active migration outside the Republic). For these reasons, Kalmykia is classified as a crisis region, since any development of its industries needs government support. The region’s economic asymmetries also lead to poverty, and the undertaken efforts aimed at its reduction have somewhat very slow-paced effects. The development asymmetries in the main economic sector of the region are rooted in climatic, economic (liquidation of large agricultural enterprises in the 1990s, local introduction of efficient means and technologies for agricultural production), and demographic factors (active migration, rural depopulation).
Khosheutovsky Ulus in the Royal Family’s Summer 1871 Travel Program: Backgrounds of Some Kalmyk Pieces from the Russian Museum of Ethnography Revisited
Authors:   Kalmyk Scientific Center of the RAS, Muchaeva Irina
Published: January 2023

Goals. The work attempts an analysis of sources constituting the program of stay of Emperor Alexander II and Tsesarevich Alexander Alexandrovich, the future Emperor Alexander III, who visited Khosheutovsky Ulus of Kalmyk Steppe (Astrakhan Governorate) in the summer of 1871 during their trip to the Caucasus. It is the ceremonial part of such travels that has made it possible to preserve most precious artifacts illustrating the material heritage of Russia’s peoples nowadays investigated by researchers representing various fields of science. Materials and methods. The chronological method in synthesis with that of reconstruction prove instrumental in considering the summer 1871 visit paid by members of Russia’s imperial house to Khosheutovsky Ulus in a time sequence, while the ideographic method helps describe the event under study. The paper focuses on documentary materials housed at the State Archive of Astrakhan Oblast and the National Archive of Kalmykia. The examined evidence also includes photographic images of showpieces from the Russian Museum of Ethnography, as well as works by pre-revolutionary and contemporary authors. Results. The distinct culture of Kalmyk Buddhists was undoubtedly attracting the attention of the monarchs. Expressing feelings of loyalty and showing respect for the reigning family, Kalmyks would present the latter with best works of decorative and applied arts of theirs that vividly illustrate nomadic lifestyles of the ethnos. Each item is characterized not only by environmental friendliness and portability — as legacy and experience of previous generations — but also bears traces of acculturation processes to have taken place in the Volga’s multiconfessional space. At present, those artefacts serve as centerpieces to collections of many museums not only in Russia but also abroad.
Land Utilization Reform Project for Kalmyk Steppe of Astrakhan Governorate in the Context of the Decree 30 December 1846: Analyzing Archival Sources of 1910
Authors:   Kalmyk Scientific Center of the RAS, Gunaev Evgeniy
Published: January 2023

Introduction. The article examines some 1910 archival documents of the Kalmyk People’s Administrative Department for provisions containing evidence that there had been a project aimed at activating land utilization across Kalmyks-inhabited territories of Astrakhan Governorate in the context of the Decree of 1846. Results. The study provides an essential-and-formal analysis of related and previously unpublished archival sources, introduces a roadmap to tackle a hypothesis and further investigate the issue. Conclusions. The addressed documents contain valuable data on land use in Kalmyk Steppe, various aspects of Kalmyks’ sedentarization, indicate ways to improve guidelines articulated in the Decree of 1846 under the early 20th-century conditions, narrate about projects for the application of land-related norms contained in imperial legislation and regulations on non-Russians of Siberia and steppe regions — to Kalmyks and their land rights. The project proclaimed the goal of further resettlement of Russian peasants to Kalmyk Steppe in dependence to land utilization patterns of Kalmyks preferred. The work postulates these issues can be investigated from the standpoint of a historical hypothesis of how the land reform would have developed (and what it would have led to) in Kalmyk Steppe had the project been implemented.
The Bashkirs by Sergey I. Rudenko: Traditional Etiquette Revisited
Authors:   Institute of History, Language and Literature, Ufa Federal Research Centre of the RAS, Baiazitova Rozaliia
Published: January 2023

Introduction. The outstanding scientist Sergei Ivanovich Rudenko (1885–1969) made an invaluable contribution to the formation and development of Bashkir ethnographic and ethnological science. The work of S. Rudenko based on personal observations, folklore samples, and studies of preceding researchers gives a general historical and ethnographic description of the Bashkir people. Goals. The article aims to identify etiquette settings, contexts of etiquette patterns presented in his monograph — The Bashkirs (1955; 2006). Results. The fundamental writing gives no special attention to traditional etiquette but some etiquette situations, attributes of etiquette are described in the context of the scholar’s research into material and spiritual culture, social and family life of the Bashkirs. Thus, the book outlines the relationship between husband and wife, older/younger male/female relatives of the latter, reviews the custom of avoidance, mealtime behaviors, some other attributes of etiquette (clothes, gifts), etc. S. Rudenko’s observations pertaining to Bashkir beliefs in the existence of soul and other world are of particular value. Conclusions. In terms of Bashkir traditional etiquette research, the scientific generalizations of S. Rudenko dealing with family, meal etiquette, and that of gift exchange are most essential. The scholar’s legacy remains as immense as it was before, and still serves as a needed source and standard for contemporary researchers.
Bayad Wedding Rites: One Manuscript from the Archives of Orientalists (Institute of Oriental Manuscripts, RAS) Analyzed
Authors:   Institute of Oriental Manuscripts of the RAS, Sabrukova Svetlana
Published: January 2023

Introduction. The article examines a manuscript describing a wedding ceremony of the Bayad Mongols who nowadays inhabit northwestern parts of Mongolia. The paper suggests the manuscript may have been authored by A. Burdukov (1883–1943). This is a Russian-language text with colloquial phrases and lexemes characteristic of the early 20th century. Goals. The article seeks to introduce the archival document of A. Burdukov as evidence of his life in Mongolia that facilitated his scholarly shaping and growth as a researcher and collector of oral and written texts representing the cultural heritage of Mongols. The manuscript is not only a source on traditional Mongolian customs and rites but is also a description of Bayad household life. The samples of minor folklore genres contained therein — such as well-wishes/blessings (Mong. yürööl) — may be instrumental for researchers to explore Mongolian vocabulary and elements of the oral tradition typical for this region. Conclusions. Three main parts within the Bayad wedding agenda can be identified from the succession of events described in the text, namely: prenuptial, nuptial, and postnuptial ones. The Bayad wedding rites contain elements similar to those of all nomadic societies and are distinguished by some livestock breeding-related attributes. The study of Mongolian traditions makes it possible to reveal both general trends of oral folklore and particular ones rooted in individual ethnocultural and historical contexts.
Ekphrasis in Contemporary Kalmyk Poetry: Exodus and Return Memorial by Ernst Neizvestny
Authors:   Kalmyk Scientific Center of the RAS, Khaninova Rimma , Valetova Elsa ,   Kalmyk Scientific Center of the RAS
Published: January 2023

Introduction. The relevance and novelty of the study be determined by that Kalmyk poetic ekphrases dealing with the deportation, exile and return of the people (1943–1957) remain underinvestigated. Goals. The article aims to identify the function of ekphrasis in poetry addressing the mentioned historical period. Materials and methods. The work focuses on two poems of Kalmykia’s national poet Ye. Budzhalov — Exodus and Return (Kalm. Буйслһн болн Босхлһн, 1997) and The Mask of Sorrow (1996) — dedicated to the monuments of E. Neizvestny in Elista and Magadan, these be supplemented with poems by R. Khaninova, V. Lidzhieva, V. Khotlin, and P. Darvaev. The subject of research is ekphrasis in contemporary Kalmyk poetry on the topic of historical memory. The employed methods include the historical / literary, historical / functional, comparative, and descriptive ones. Results. In contemporary Kalmyk poetry, the theme of the Elista-based monument created by E. Neizvestny is reflected in two poems by Yegor Budzhalov, as well as in narratives of other Russian–language Kalmyk poets, such as Rimma Khaninova (Neizvestny — A Requiem Two Steps away from the One Who Authored the Exodus and Return Memorial, 1996), Valentina Lidzhieva (Monologue of the Father, 1997), Valery Khotlin (Exodus, 1998), and Pyotr Darvaev (To the Exodus and Return of Ernst Neizvestny, 2009). Conclusions. Despite that Ye. Budzhalov created the two poems having attended the opening ceremonies of those monuments by the renowned sculptor in Magadan and Elista, ekphrasis in his works is reduced to some minimalist and laconic techniques, its plot-forming function as one depicting the sculptural artefacts serving rather a starting point for the author’s thoughts on personal experiences of the Siberian exile and ethnic genocides in the era of Stalinist repressions. The poems of the Russian–language Kalmyk poets born during and at the end of the Siberian exile (P. Darvaev, V. Khotlin, R. Khaninova), or after the people’s return to their homeland (V. Lidzhieva) articulate ekphrasis to varying degrees — through verbal depictions of the monument in connection with its author. So, the Kalmyk poets have evidently created no mother-tongue ekphrases to capture such a significant event, which may be explained by that the artefact is actually too difficult to describe through the prism of ekphrasis and its tools.
Sociodemographic Asymmetries across Regions of South Russia: Analyzing Statistical Data
Authors:   Kalmyk Scientific Center of the RAS, Namrueva Ludmila
Published: January 2023

Goals. The article attempts an analysis of sociodemographic asymmetries across the regions of South Russia (Republic of Kalmykia, Astrakhan, Volgograd, and Rostov Oblasts). Materials. The work examines available statistical data on a number of indicators, such as population number, fixed assets value, gross average accrued monthly wages, per capita average monthly money income, income inequality. Results. The insights into statistical accounts attest to there are evident asymmetries within economies of the regions under review, the latter being characterized by low incomes, poverty, and pronounced income inequality. The paper suggests the main reasons underlying the regions remain that economically troubled are low wage and income levels, rampant unemployment that result in residents tend to become more migration-minded.
Evgeny Lukin and Sergey Sinyakin: The Means Employed by Volgograd-Based Writers to Create Local Text Revisited
Authors:   Volgograd State Socio-Pedagogical University, Putilo Oleg
Published: January 2023

Goals. The article aims to examine works of Evgeniy Lukin and Sergey Sinyakin for artistic features inherent to Tsaritsyn, Stalingrad, and Volgograd local texts. Results. Despite the commonness of geographical coordinates, the techniques employed by the two authors to create local texts relating to both realistic and fantastic fiction are different. The realistic depiction of Stalingrad’s contexts is primarily determined by patriotic interpretations of the city’s image that afford no satirical depreciation, while the Volgograd and Tsaritsyn texts may include some particular elements of the comic. In fantastic narratives of Evgeniy Lukin and Sergey Sinyakin, local text is organized through the contamination of original spatial images and their comic transformations as a result of the postmodern ‘game with the reader”.
Factores motivacionales que determinan el emprendimiento de las mujeres en Tabasco, México
Authors: Miranda Sánchez Jennifer Darvelia , Sandoval Caraveo María del Carmen , Berttolini Díaz Gilda María
Published: February 2023

Objetivo: identificar la motivación para el emprendimiento de las empresarias de Tabasco, México. Metodología: estudio cuantitativo descriptivo con muestreo no probabilístico a conveniencia del investigador. Resultados: participaron 212 empresarias. Se identificaron las motivaciones de su emprendimiento: la obtención de ingresos mediante un negocio propio y, en menor medida, el emprendimiento como un medio para conseguir seguridad económica a largo plazo. Limitaciones: por ser un estudio no probabilístico, los resultados solo corresponden a las participantes. Se requiere más profundidad y análisis de otras variables para obtener hallazgos más detallados. Valor: la investigación contribuye al análisis de la participación de las mujeres en la economía local y se podría replicar para identificar su motivación en otros contextos. Conclusiones: la motivación para el emprendimiento puede coadyuvar al desarrollo de esfuerzos para incentivar la participación de las mujeres y favorecer el progreso y la permanencia de sus negocios.
Un procedimiento para la obtención de los espectros IR, Raman y RMN de compuestos orgánicos mediante cálculos mecánico-cuánticos con el software ORCA-5.0.3
Authors: Parra Figueredo José Gregorio , González José , Perozo Elizabeth , Iza Peter
Published: February 2023

Este manuscrito describe un procedimiento para la estimación de los espectros IR, Raman y RMN de H1 y C13 de especies orgánicas mediante el uso de cálculos mecánico-cuánticos con la finalidad de mostrar a estudiantes universitarios la implementación de técnicas de simulación en la elucidación de sus estructuras moleculares. Los softwares Avogadro-1.2.0 (Hanwell et al., 2012) y Orca-5.0.3 (Neese, 2018) fueron utilizados para la elaboración de este procedimiento. Este estudio muestra que las frecuencias vibracionales armónicas y las intensidades de las señales estimadas para los espectros Infrarrojos fueron aceptables y en correspondencia con los valores experimentales. En cambio, las intensidades del espectro Raman presentaron desviaciones considerables que pueden atribuirse al enfoque utilizado para la estimación de las intensidades del espectro y la realización de los cálculos mecánico-cuánticos en el vacío para las moléculas seleccionadas. Finalmente, las señales de los espectros RMN de H1 y C13 fueron obtenidos con una muy buena estimación, lo cual fue corroborado con los valores de RMSE reportados.
Versátil como ninguna, la química clic y su trascendencia en áreas diversas: de la ciencia de materiales a la investigación farmacéutica
Authors: Guadarrama Acosta Patricia , López-Méndez Luis José , Cabrera-Quiñones Neyra Citlali , Cruz-Hernández Carlos Alberto
Published: February 2023

En el año 2022 se otorgó el premio Nobel de química a Carolyn R. Bertozzi, Morten Meldal y K. Barry Sharpless por sus aportaciones en el desarrollo de la química clic y la química bioortogonal. La trascendencia de este tipo de reacciones radica en que, por su sencillez, selectividad, eficiencia y tolerancia a diferentes medios, incluido el acuoso, ha impactado no sólo en la química sintética de moléculas complejas y materiales, sino también en el área farmacéutica, ya que, aplicando este tipo de reacciones es posible formar conjugados con biomoléculas como proteínas, abriendo la puerta a la exploración y comprensión de diversos procesos biológicos en los organismos vivos para acceder así a terapias dirigidas más eficientes. En el Instituto de Investigaciones en Materiales de la UNAM hemos aplicado esta reacción de manera exitosa para modificar directamente algunas moléculas bioactivas como la curcumina (antioxidante natural), mejorando sus propiedades fisicoquímicas como solubilidad y estabilidad química. Asimismo, aplicando reacciones clic se sintetizaron derivados de β-ciclodextrina como nuevos acarreadores de fármacos, incorporando sustituyentes altamente ramificados llamados dendrones que confieren un adecuado balance hidrofílico/hidrofóbico. Estas modificaciones nos permitieron optimizar su paso a través de las membranas celulares por difusión, y su capacidad para encapsular fármacos hidrofóbicos.
Dependence of polyethylene combustion dynamics in a 1 m3 chamber on particle size
Authors: Poletaev N. L.
Published: February 2023

Introduction. The results of a standard study on the explosion hazard of polyethylene air suspensions (PES) can contribute to the theory of turbulent combustion. For example, analysis of polydispersity data and values of the PES lean combustion limit in a 1 m3 chamber helped to identify the maximum size of explosive particles d*m,t ≈ 100 µm (Poletaev, 2014). In this work, a relationship was obtained between the dynamics of PES combustion in a 1 m3 chamber and the average particle size of the suspension, which is understood as the average particle size of its explosive fraction d*50.

Initial data. Well-known findings of a study on the explosion of 28 polyethylene specimens in a 1 m3 chamber were used. Continuous functions of specimen particles distribution by size, necessary for calculating d*50, were represented using the Rosin-Rammler distribution.

Combustion dynamics. The dynamics of PES turbulent combustion in a 1 m3 chamber is described by the maximum rate of air suspension burnout Ub. Ub was calculated according to the formula (Kumar, 1992) intended for gas-air mixtures by substituting PES explosion parameters into this formula.

Results and its discussion. The graph, describing the dependence of the complex d*50Ub on d*50, is provided. The averaged value of the complex (≈ 45 µm · (m/s)) is constant in the range 40 µm < d*50 < 90 µm. The latter is typical for the product of the particle size and the normal velocity of laminar flame in liquid aerosols (Myers, 1986), which indicates similarity between the effect of particle dispersion and dynamics of turbulent and laminar combustion of the aforementioned heterogeneous mixtures.

Conclusions. The dispersive capacity of an explosive polydisperse polyethylene specimen is determined by the average particle size of the explosive fraction of the specimen d*50. The similarity of combustion patterns indicates the proximity of propagation mechanisms typical for turbulent flame, typical for PES, and laminar flame, typical for liquid aerosols.
Statistical analysis of accidents at filling stations
Authors: Ivakhnyuk G. K. , Osmonov Yu. Yu.
Published: February 2023

Introduction. The number of accidents at gas stations has increased lately. Gas stations provide maintenance and fueling services. Gas stations are dangerous because they store fire hazardous automobile fuel, as well as equipment under pressure that may contain explosive gases. For safety reasons, it is necessary to analyze the causes of these accidents. The purpose of the work is to conduct a statistical analysis of accidents at gas stations to identify patterns of accidents.

Analysis. The article presents the statistics of accidents at service gas stations in the Russian Federation for 10 years from 2012 to 2021. The data is provided by the National Crisis Management Centre of the Ministry of the Russian Federation for Civil Defense, Emergencies and Elimination of Consequences of Natural Disasters (Emercom of Russia). The analysis of accidents at gas stations is broken down by the constituent entities of the Russian Federation. Causes of fires are indicated; ignition sources are considered, locations of fires and facilities are listed. Fires at gas stations were considered taking into account the categorization of objects in accordance with government decree “On Application of a Risk-Oriented Approach to Organization of Certain Types of State Control (Supervision)”.

Conclusion. The statistics, provided and analyzed in the article, can serve as the basis for a scientific research project on the fire safety of gas stations.
Influencing factors of drinking by gender of adolescents in single-parent households: Data from the 17th Korean Youth Risk Behavior Survey
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park Mi-Ran , Yun Kyoungsun
Published: January 2023

Objectives This study aimed to analyze the drinking level and influencing factors according to the gender of adolescents from single-parent households.
Methods A total of 764 adolescents were selected and analyzed using the 17th Korean Youth Risk Behavior Survey. The Rao-Scott chi-square test was conducted to examine the differences in demographic characteristics, drinking, and health risk behavior according to gender of single parent household adolescents, and the differences in demographic and health risk behavior according to drinking. and complex sample logistic regression was performed for factors affecting drinking according to gender.
Results As a result of analyzing the data of 330 female students and 434 male students from single-parent households, 53.3% of female students and 52.3% of male students in single-parent households were drinking. The factor influencing drinking among female students from single-parent households was current smoking, which was 5.89 times more likely to drink than non-smoker female students. The factors influencing drinking among male students from single-parent families were subjective body type, current smoking, and sexual experience. Male students who considered themselves to be thin drank 0.75 times more than male students who considered themselves normal, smokers 4.92 times more than non-smokers, and students with sexual experience 2.41 times more than non-sexual experience.
Conclusions Based on the results of this study, differentiated education program according to the gender of adolescents from single-parent households is needed, and continuous attention from home and school is needed so that adolescents from single-parent households can grow up healthy.
The Effect of Children's Smartphone Dependence on Cyber Delinquency and Real Delinquency: Focusing on the Mediating Effect of Cooperation
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kwon Heekyoung , Hyeyoung Jo Hyeyoung
Published: January 2023

Objectives The purpose of this study is to verify the mediating effect of cooperation in the process of children's dependence on smartphones affecting cyber delinquency and real delinquency.
Methods The subjects of the study are 2,404 first-year middle school students, which are panel data for the second year (2019) of ｢the Korean Children and Youth Panel Survey (KCYPS) 2018｣. The relationship among the research variables was examined with Pearson correlation using SPSS 25.0 and AMOS 23.0, and the influence and the mediating effect were analyzed by structural equation. The direct and indirect effects and total effects were verified by two-sided test using bootstrap in the 95% confidence interval.
Results The main results are as follows. First, real delinquency has a positive correlation with smartphone dependence, while the first and second factors of cooperation has a negative correlation. Cyber delinquency showed a positive correlation with smartphone dependence. On the other hand, the first and second factors of cooperation has a negative correlation. Second, it was found that smartphone dependence directly affects cyber and real delinquency, and cooperation is partially mediated in this process.
Conclusions The results of this study confirm that smartphone dependence is an important factor in the process of affecting real delinquency and cyber delinquency, suggesting that it is necessary to find ways for cooperative activities for children.
Analysis of essays on college students’ experiences with non-face-to-face education
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park Hyojin , Ju Hyunjung
Published: January 2023

Objectives The purpose of this study was to explore the perceptions of college students about non-face-to-face education by using text mining techniques.
Methods A total of 35 essays on college students’ experiences with non-face-to-face education were collected and analyzed using term frequency and latent Dirichlet allocation (LDA)-based topic modeling.
Results The result of the term-frequency analysis revealed that keywords, such as society, participation, utilization, school, and method, were prominent ones. The LDA-based topic modeling generated eight topics: presence, safety, the right to learn, communication, technological limitation, space-time flexibility, learning gap, and sense of belonging and adaptation to college life.
Conclusions The results of this study can help broaden the perceptions of college students’ experiences with non-face-to-face education and provide implications for enhancing the quality of non-face-to-face education.
Probing sign structure using measurement-induced entanglement
Authors: Lin Cheng-Ju , Ye Weicheng , Zou Yijian , Sang Shengqi , Hsieh Timothy H.
Published: February 2023

The sign structure of quantum states is closely connected to quantum phases of matter, yet detecting such fine-grained properties of amplitudes is subtle. Here we employ as a diagnostic measurement-induced entanglement (MIE): the average entanglement generated between two parties after measuring the rest of the system. We propose that for a sign-free state, the MIE upon measuring in the sign-free basis decays no slower than correlations in the state before measurement. Concretely, we prove that MIE is upper bounded by mutual information for sign-free stabilizer states (essentially CSS codes), which establishes a bound between scaling dimensions of conformal field theories describing measurement-induced critical points in stabilizer systems. We also show that for sign-free qubit wavefunctions, MIE between two qubits is upper bounded by a simple two-point correlation function, and we verify our proposal in several critical ground states of one-dimensional systems, including the transverse field and tri-critical Ising models. In contrast, for states with sign structure, such bounds can be violated, as we illustrate in critical hybrid circuits involving both Haar or Clifford random unitaries and measurements, and gapless symmetry-protected topological states.
Local hidden variable values without optimization procedures
Authors: Goyeneche Dardo , Bruzda Wojciech , Turek Ondřej , Alsina Daniel , Życzkowski Karol
Published: February 2023

The problem of computing the local hidden variable (LHV) value of a Bell inequality plays a central role in the study of quantum nonlocality. In particular, this problem is the first step towards characterizing the LHV polytope of a given scenario. In this work, we establish a relation between the LHV value of bipartite Bell inequalities and the mathematical notion of excess of a matrix. Inspired by the well developed theory of excess, we derive several results that directly impact the field of quantum nonlocality. We show infinite families of bipartite Bell inequalities for which the LHV value can be computed exactly, without needing to solve any optimization problem, for any number of measurement settings. We also find tight Bell inequalities for a large number of measurement settings.
拉脱维亚线上汉语教学纵论 = A Study of Online Chinese Teaching in Latvia
Authors: Bingyu Bai
Published: January 2023

本书是第一部探讨拉脱维亚线上汉语教学的著作, 涉及线上汉语教学总体研 究、中小学中文课堂“线上双师教学”模式研究、线上汉语综合课教学设计与应用 研究、地域文化线上教学研究、线上汉语教学课堂管理研究, 此外也涉及基于“欧框”(CEFR)的初级汉语综合 课教学设计与应用研究、汉语教学情况调查与研究。
Impact of a Community-Based Weight Management Program in a North Carolina Health Care System
Authors: Ro Sarah J. , Lackey Angelica R. , Aymes Shannon E. , McCauley Jennifer L. , Davis Teneisha C. , Wang Raene , Stanley Will , Ratner Shana P. , Machineni Sriram , Fiscus Lynne C.
Published: January 2023

Background and Objectives:  Current strategies for obesity management in primary care leave many patients inadequately treated or unable to access treatment entirely. We aimed to evaluate a comprehensive, primary care clinic-based weight management program’s clinical effectiveness in a community practice setting. 
Methods:  This was an 18-month pre/postintervention study. We collected demographic and anthropometric data on patients enrolled in a primary care-based weight management program. The primary outcomes were percent weight loss postintervention and the proportion of patients who achieved a clinically significant total body weight loss (TBWL) of 5% or greater. 
Results:  Our program served 550 patients over 1,952 visits from March 2019 through October 2020. A total of 209 patients had adequate program exposure, defined as four or more completed visits. Among these, all received targeted lifestyle counseling and 78% received antiobesity medication. Patients who attended at least four visits had an average TBWL of 5.7% compared to an average gain of 1.5% total body weight for those with only one visit. Fifty-three percent of patients (n=111) achieved greater than 5% TBWL, and 20% (n=43) achieved greater than 10% TBWL.
Conclusion:  We demonstrated that a community-based weight management program delivered by obesity medicine-trained primary care providers effectively produces clinically significant weight loss. Future work will include wider implementation of this model to increase patient access to evidence-based obesity treatments in their communities.
Republic of Tyva: Interaction of Languages in the Context of Language Construction
Authors:   Institute of Mongolian Studies, Buddhology and Tibetology of the Siberian Branch of the Russian Academy of Sciences, Tsybenova Chechek S.
Published: January 2023

The article is devoted to the issues of functional distribution of Tuvan and Russian languages in the social and communicative system of the Republic of Tyva. Functional relationship of these languages is considered in the language policy context of the Russian Federation. Data of various population censuses and data of a sociolinguistic study conducted by the author with native speakers of the Tuvan language in 2009–2010 are presented. The results of analysis show that functionally powerful Russian language has a significant impact on respondents’ degree of linguistic loyalty and level of linguistic competence. Obtained data indicate increase of bilingual native speakers among Tuvans, increase in their level of linguistic competence in Russian, a change in language attitudes of younger generation of Tuvans. It is said that programs for development and preservation of the Tuvan language are declarative in nature, aimed solely at achieving indicators. It is noted that active language environment contributes to mastery of the Tuvan language in family and at school. Such factors as language policy in the field of education and unbalanced language situation lead to a gradual transformation of linguistic consciousness and language attitudes of Tuvan youth and have a serious impact on development and preservation of the Tuvan language.
Digital Presence: Prospects for the Vitality of a Regional Language
Authors:   Kazan State Power Engineering University, Yanush Olga B.
Published: January 2023

The article notes that the digital world is an important context for the use and functioning of languages. At the same time, virtual space is linguistically less diverse than offline space. Along with the existing systems for determining the vitality of language, researchers are making attempts to determine the digital vitality of languages. In other words, we are talking about the digital wellbeing of the language and reliable indicators of the success of the language in the virtual space. Among the important indicators of the digital vitality of the language, the number of the digital population measured by social media accounts is noted; the use of the language by global brands; technological conditions associated with the widespread penetration of the Internet; a large number of sites in the language; a localized version of social media; the use of the language in blogs and other means of social communication (e-mail, chats, forums, etc.); the existence of machine translation tools for this language, etc. The article provides an overview of the models of digital vitality developed by foreign researchers. We are talking about the online research of A. Kornai, the approaches of M. Gibson and the Digital Linguistic Diversity Project of the Institute of Computational Linguistics of Italy. The described models are applicable to the definition and promotion of the digital presence of the languages of the peoples of Russia.
Strategy for the Promotion of World Languages in Central Asia in the Context of the Belt and Road Initiative
Authors:   Eastern Europe and Central Asia Institute, Bo Yang
Published: January 2023

Central Asia is the region where the Belt and Road Initiative was first proposed and is of strategic importance to China. The realization of Chinese interests in the region is impossible without effective consultations and mutual understanding. The position of the Chinese language in Central Asia is not strong due to a number of cultural and historical reasons, and it is particularly relevant to study and borrow from global experience in the promotion and popularisation of international languages in the Region. This paper focuses on assessing the status of world languages in Central Asia, comparing the concepts and tools of their promotion, and analysing the challenges of Chinese language promotion in the region.