bluuebunny/crossref_metadata_2025 huggingface dataset:
Machine Learning for Prediction of Patients on Hemodialysis with an Undetected SARS-CoV-2 Infection
Authors: Monaghan Caitlin K. , Larkin John W. , Chaudhuri Sheetal , Han Hao , Jiao Yue , Bermudez Kristine M. , Weinhandl Eric D. , Dahne-Steuber Ines A. , Belmonte Kathleen , Neri Luca , Kotanko Peter , Kooman Jeroen P. , Hymes Jeffrey L. , Kossmann Robert J. , Usvyat Len A. , Maddux Franklin W.
Published: January 2021

Background

We developed a machine learning (ML) model that predicts the risk of a patient on hemodialysis (HD) having an undetected SARS-CoV-2 infection that is identified after the following ≥3 days.

Methods

As part of a healthcare operations effort, we used patient data from a national network of dialysis clinics (February–September 2020) to develop an ML model (XGBoost) that uses 81 variables to predict the likelihood of an adult patient on HD having an undetected SARS-CoV-2 infection that is identified in the subsequent ≥3 days. We used a 60%:20%:20% randomized split of COVID-19–positive samples for the training, validation, and testing datasets.

Results

We used a select cohort of 40,490 patients on HD to build the ML model (11,166 patients who were COVID-19 positive and 29,324 patients who were unaffected controls). The prevalence of COVID-19 in the cohort (28% COVID-19 positive) was by design higher than the HD population. The prevalence of COVID-19 was set to 10% in the testing dataset to estimate the prevalence observed in the national HD population. The threshold for classifying observations as positive or negative was set at 0.80 to minimize false positives. Precision for the model was 0.52, the recall was 0.07, and the lift was 5.3 in the testing dataset. Area under the receiver operating characteristic curve (AUROC) and area under the precision-recall curve (AUPRC) for the model was 0.68 and 0.24 in the testing dataset, respectively. Top predictors of a patient on HD having a SARS-CoV-2 infection were the change in interdialytic weight gain from the previous month, mean pre-HD body temperature in the prior week, and the change in post-HD heart rate from the previous month.

Conclusions

The developed ML model appears suitable for predicting patients on HD at risk of having COVID-19 at least 3 days before there would be a clinical suspicion of the disease.
Effect of Cellular-Based Artificial Antigen Presenting Cells Expressing ICOSL, in T-cell Subtypes Differentiation and Activation
Authors: Talebi Mehdi , Nozad Charoudeh Hojjatollah , Movassagpour Akbari Ali Akbar , Baradaran Behzad , Kazemi Tohid
Published: January 2021

Purposes: Effective and selective T-cell activation and proliferation during the T-cell expansion phase of a cellular adoptive immunotherapy method, challenging because recent studies revealed the importance of each subtype of T-cells in different immunologic strategies against tumors, like CAR-T cell therapies. Artificial Antigen Presenting Cells regarded as a natural way to manipulate T-cell subtypes activation and specific proliferation. In the current study, we utilized K562 cells based aAPC method expressing the ICOSL molecule, to evaluate T-cell subtypes differentiation rate and functional status. Methods: CD3+T-cells isolated and, co-cultured with ICOSL expressing K562 cells. After 4, 6, and 10 days selective CD markers of T-cell subtypes and each subtype’s activity-related genes levels evaluated by qPCR methods. Results: During the culture period, CD4+ Th related phenotype reduced continuously, and in day 10th of culture CD4+ T-cell’s population significantly reduced (p=0.029). In contrast, the CD8+ population ratio was ascending during the study period but was not statistically significant. FoxP3+CD25-, Treg population ratio was significantly increased during the time in comparison with the control group, as well as memory T-cell phenotypic marker, CD127+, expressing cells ratio. T-cell subpopulations activity-related genes expression levels evaluated too, and the Th1 related IL-2 and INF-γ reductions observed alongside regulatory T-cells gene (IL-10) and Cytotoxic T-cell’s related gene (Geranzym-A) elevations. Conclusion: We concluded that the K562-ICOSL based aAPC system is working and effective in T-cell short to medium culture periods, and this approach preparing relatively selective milieu for CD8+ T-Cell differentiation and much less Treg differentiation.
Biosurfactant Production Using Mutant Strains of Pseudomonas aeruginosa and Bacillus subtilis from Agro-industrial Wastes
Authors: Adejumo Samson A. , Oli Angus Nnamdi , Okoye Ebere Innocent , Nwakile Calistus Dozie , Ojiako Chioma Miracle , Okezie Ugochukwu Moses , Okeke Ifeanyi Justin , Ofomata Chijioke M. , Attama Anthony A. , Okoyeh Jude N. , Esimone Charles Okechukwu
Published: January 2021

Purpose: Biosurfactants are applied in drug formulations to improve drug solubility and in some cases, treat diseases. This study is focused on generating, extracting, purifying and then characterizing biosurfactants from bacterial isolates of palm oil wastes and abattoir soil origins. Methods: Eight (8) bacteria were isolated from the soil and sludge samples, out of which four (50 %) were found to produce biosurfactants. Bacillus subtilis (37.5 %) and Pseudomonas aeruginosa (50%) were isolated and identified from these samples using mineral salt medium, nutrient agar and Cetrimide agar. Mutant isolates of Bacillus subtilis BS3 and Pseudomonas aeruginosa PS2 were used to produce biosurfactants using mineral salt medium as enrichment medium and extraction was done using membrane filter. Results: The mutant strains Bacillus subtilis BS3 and Pseudomonas aeruginosa PS2generated biosurfactants that displayed significant solubility and dissolution properties by enhancing the percentage solubility of piroxicam to 62.86 and 54.29 % respectively, and achieved 51.71 and 48.71 % dissolution of the drug in 0.1N HCl. Conclusion: From the results obtained, the produced biosurfactants could serve as a better alternative to conventional surfactants. Notably, the study indicated that the biosurfactant produced by mutant strain of Bacillus subtilis produced more potent activities (surface tension reduction ability, high emulsification) than those of Pseudomonas aeruginosa. Keywords: Biosurfactant production; Bacillus subtilis; Pseudomonas aeruginosa; Microbial Biotechnology; Palm oil wastes; Abattoir soil
Breast Cancer: a Global Concern, Diagnostic and Therapeutic Perspectives, Mechanistic Targets in Drug Development
Authors: Chaudhry Gul-e-Saba , Jan Rehmat , Akim Abdah , Zafar Muhammad Naveed , Sung Yeong Yik , Muhammad Tengku Sifzizul Tengku
Published: January 2021

Cancer is a complex multifactorial process, unchecked and abrupt division, and cell growth—conventional chemotherapy, along with radiotherapy, is used to treat breast cancer. Due to reduce efficacy and less survival rate, there is a particular need for the discovery of new active anticancer agents. Natural resources such as terrestrial/marine plants or organisms are a promising source for the generation of new therapeutics with improving efficacy. The screening of natural plant extracts and fractions, isolations of phytochemicals, and mechanistic study of those potential compounds play a remarkable role in the development of new therapeutic drugs with increased efficacy. Cancer is a multistage disease with complex signaling cascades. The initial study of screening whole extracts or fractions and later the isolation of secondary compounds and their mechanism of action study gives a clue of potential therapeutic agents for future drug development. The phytochemicals present in extracts/fractions produce remarkable effects due to synergistically targeting multiple signals. In this review, the molecular targets of extracts/ fractions and isolated compounds highlighted. The therapeutic agent's mechanistic targets in drug development focused involves; i) Induction of Apoptosis, ii) modulating cell cycle arrest, iii) Inhibition or suppression of invasion and metastasis and iv) various other pro-survival signaling pathways. The phytochemicals and their modified analogs identified as future potential candidates for anticancer chemotherapy.
Ligament/Tendon Culture under Hypoxic Conditions: A Systematic Review
Authors: Rhatomy Sholahuddin , Utomo Dwikora Novembri , Prakoeswa Cita Rosita Sigit , Rantam Fedik Abdul , Suroto Heri , Mahyudin Ferdiansyah
Published: January 2021

The hypoxic environment is a substantial factor in maintenance, proliferation, and differentiation of the cell cultures. Low oxygen is known as a potent chondrogenesis stimulus in stem cells that is important for clinical application and engineering of functional cartilage. Hypoxia can potentially induce angiogenesis process by secretion of cytokines. This systematic review goal is to discover the effect of hypoxic condition on tendon/ ligament culture and the best oxygen level of hypoxia for in vitro and in vivo studies. We included 21 articles. A comprehensive review of this database confirms that the hypoxic condition is a substantial factor in the maintenance, proliferation, and differentiation of ligament/tendon cultures. Cell proliferation in the severe hypoxic (oxygen concentration of 1%) group at 24 h postcultivation was considered significant, but cell proliferation was markedly inhibited in the severe hypoxic group after 48 h.
Up-Regulation of Cell-Free MicroRNA-1 and MicroRNA-221-3p Levels in Patients with Myocardial Infarction Undergoing Coronary Angiography
Authors: Mansouri Fatemeh , Seyed Mohammadzad Mir hosein
Published: January 2021

Purpose: Myocardial infarction (MI), known as a multifactorial disease, remains the predominant cause of mortality and sudden deaths annually. The current study aimed to measure the expression of microRNA-1 and microRNA-221-3p in MI patients. Methods: In the current study, 100 healthy controls (with no history of heart disease) and 200 patients with MI were selected. Patients were divided into two groups based on angiography results: normal (no significant artery stenosis) and primary percutaneous coronary intervention (primary PCI, significant artery stenosis). The levels of microRNA-1 and microRNA-221-3p were quantified using real-time quantitative polymerase chain reaction. The correlation between levels of microRNAs and the common cardiac markers were analyzed statistically. Results: In comparison to fold change, microRNA-1 elevations were 8.5-fold in normal patients and 60-fold in patients with primary PCI; while microRNA-221-3p levels were 210- fold higher in primary PCI and 31.31-fold higher in normal cases compared with the healthy controls. Receiver operating characteristic analysis showed that the area under the curve (AUC) for circulating microRNA-1 and microRNA-221 were 0.903 and 0.958 in normal patients and 0.927 and 0.985 in primary PCI patients (p <0.0001), respectively. Pearson correlation (ρ) analysis showed that circulation of microRNA-1 correlated with serum levels of cardiac troponin I (CTnI) (ρ=0.24), creatinine (ρ =0.34), creatinine kinase-myocardial band (CK-MB) (ρ=0.31), and microRNA-221-3p was significantly correlated with serum levels of CTnI (ρ =0.6), creatinine (ρ=0.41), and CK-MB (ρ=0.37), (P <0.0001). Conclusion: The study underscored the potential of microRNA-1 and microRNA-221-3p as informative biomarkers and positively correlated with artery stenosis in MI.
Solid State Characterization and Dissolution Enhancement of Nevirapine Cocrystals
Authors: Panzade Prabhakar , Shendarkar Giridhar , Kulkarni Deepak , Shelke Santosh
Published: January 2021

Purpose: Novel cocrystals of nevirapine (NP) were designed and prepared with salicylamide and 3-hydroxy benzoic acid (3-HBA). Methods: The cocrystals were prepared by solvent drop grinding method by adding few drops of acetone to enhance the solubility and dissolution. The drug and cocrystals were characterized by differential scanning calorimetry (DSC) and powder x-ray diffraction (PXRD). The solubility of NP, its wet ground form, and cocrystals were investigated at different pH. Moreover, the effect of surfactant on solubility of cocrystals was also studied. Finally, intrinsic dissolution rate (IDR) and stability of cocrystals was examined. Results: The characterization of cocrystals by DSC and PXRD revealed formation of new solid forms due to changes in thermogram and PXRD pattern. The cocrystal of NP with 3-HBA showed 4.5 folds greater solubility in pH 1.2 buffer and 5.5 folds in 1% Tween 80 as compared to original drug. IDR of cocrystals was higher than the pure drug in 0.1 N hydrochloric acid (HCl). Moreover, cocrystals were found physically stable after 3 months as evident from unchanged IDR. Conclusion: Hence, the present research indicates the new stable solid forms of NP with improved dissolution rate than pure drug.
Knowledge Acquisition and Meaning‑making in the Participatory
Budgeting of Local Governments
Authors: Bocatto Evandro , Perez-de-Toledo Eloisa
Published: January 2021

The participatory budgeting of Brazilian municipalities is
one of the most publicized examples of democracy‑in‑action that
fosters citizenship knowledge acquisition in local government. This
research adds two new perspectives to the participatory process. The
first one demonstrates how knowledge is acquired and shared, and
which are the new contextual conditions for this acquisition to
happen, which we call, the knowledge acquisition process. At second,
we explain the meaning‑making process as a subjective way to acquire
knowledge about oneself, the others, and the democratic systems.
Citizens, public servants, policy‑makers, and politicians acquire
new meanings for the role they play in local government and become
reengaged on democracy through the ontological change from
representative to participatory and deliberative democracy. In this
qualitative research, our methodological bricolage relies on the
triangulation of methods (i.e. documentation review and observations
of behaviors and procedures; in‑depth‑interviews; and, focus groups)
and sources (i.e. comparison of cases, and stakeholders). The
bricolage deconstructs these social actions on their constituents,
vis‑a‑vis hidden intentions; instruments; and, implementation. Among
the several Brazilian cases, this longitudinal study (i.e. 12 years)
concentrates on five of them. Our findings suggest that the
participation in the process allows for a change on individuals’
understanding of democracy, enhances citizenship knowledge
acquisition, reframes the meaning of citizenship, and improves the
quality of relationships among the stakeholders involved. In the
participatory budgeting, citizens learn, what critical theory calls
“to emancipate”. They act as if they were members of an ideal
kingdom of ends in which they were both subjects and sovereigns at
the same time, which guarantees citizenship engagement, learning and
development.
Let the Data Speak: Using Rigour to Extract Vitality from
Qualitative Data
Authors: Campbell Alistair J
Published: January 2021

Qualitative data can be gathered from an array of rich
sources of research information. One of the popular ways to collect
this data is by interviewing a range of experts on the topic,
followed by transcription, resulting in a database of written
documents, often supplemented by other documented data that informs
the topic. Thematic or Content Analysis can then be used to explore
the data and identify themes of meaning that enlighten the research
topic, with the themes being gathered into nodes. The researcher now
has an array of nodes, which needs to be organised into a coherent
model, and more importantly, one that represents the views of the
research informants. To do this with some degree of rigour, the
researcher needs some way of ranking the nodes in terms of their
relative importance. The node ranking can be based on experience, or
on the literature, but neither of these approaches looks to the data
itself. If the database contains new or unexpected knowledge,
neither experience nor the literature will guide us to it, and vital
new insights may easily be missed. The framework outlined in this
paper aims to provide a sound first‑cut analysis of the data, based
on the evidence in the research interviews themselves. Clearly the
literature and research experience have an important role to play in
shaping the results of any research. However this paper argues that
one should proceed only after the data itself has been offered "the
first chance to speak".The node classification matrix detailed here,
identifies distinct node categories, each ranging in significance
and with particular characteristics that reveal key aspects of the
informants' views. In this way the researcher can use the nodes to
reveal the voice of the experts, and build a scientifically rigorous
set of results from a qualitative database.
Building Creative Critical Online Learning Communities
through Digital Moments
Authors: Barber Wendy
Published: January 2021

This paper is a mixed methods case study measuring student
perceptions of a pedagogical strategy called “Digital Moments” (DM)
for developing creative interactive online learning communities. The
theoretical framework within which this resides is the Fully Online
Learning Community (FOLC) model (vanOostveen et al, 2016), based on
a foundation of problem‑based learning, cognitive and social
presence, and learner‑centred pedagogies.The article reviews a
specific teaching strategy for increasing social presence and
student engagement through the use of creative and artistic
expression in problem‑based learning spaces. Using “Digital Moments”
as a way to build inclusion in two synchronous graduate online
courses, the author describes how the teaching strategy increased
student participation, developed student ownership of learning, and
encouraged collaborative processes between participants. This
teaching strategy makes a significant contribution to digital
pedagogy. Although the growth of online learning is quite
substantial, our ability to develop online communities that inspire
critical and creative thinking has not kept pace. Traditional
teacher‑centred learning environments do not meet the needs of
students in today’s Fourth Industrial Revolution. As such, the FOLC
model provides an online learning community model that removes
traditional teacher‑learner roles, allows the instructor to act as a
facilitator and challenges learners to co‑design and co‑create the
learning process. Within this digital space, collaborative
disruption is encouraged, and, in fact necessary for the types of
critical and creative thinking to emerge that are central to the
FOLC model. Digital Moments, is one example of a pedagogical
strategy that enables learners to co‑create and own the digital
learning space, within a fully online learning community.
Engagement with and Participation in Online role play
Collaborative Arguments: A Sociocultural Perspective
Authors: Najjemba Josephine Lutaaya , Cronjé Johannes
Published: January 2021

Digitally mediated role plays indicate potential for
collaboration, social exchange of information and knowledge as well
as motivation for learning beyond classroom time. These elements are
critical for ESL learners’ development of language and argumentative
writing practices. The aim of this research project was to
investigate how students’ engagement with and participation in
online role play collaborative arguments shaped their literacy
practices, and influenced their beliefs and thinking regarding
particular societal issue. This qualitative research project based
on a larger ethnographic case study and tools of action research
investigated students’ interactions and experiences before, during
and after the online role play. The study involved 20 ESL
pre‑service students at one university in Uganda and was conducted
in both the real and online spaces. The real space involved
face‑to‑face sessions aimed at building students’ confidence in
using blogs for online role play. While the online space involved
non‑participant observations to gain understanding of the social
dynamics of students’ engagement in online role play, and the
opportunities for students to engage in literacy practices related
to online argumentative compositions. The study findings indicated
that engagement in online role play using blog platform provided a
rich environment for learners to exercise their creativity,
orchestrate multiple ways of meaning‑making and build tactical
relations for purposes of collective action. Furthermore, the use of
online role play collaborative arguments facilitated a shift from
“ascribed” to “achieved” identities where students did not only
become aware that they were dealing with issues larger than
individual perspectives, associated with school, family, culture and
the legal system, but also that there need for them to take part in
the civic action.
Kırcali Ağzı Örneğinde Doğu Rumeli Ağzının Batı Anadolu Bölge Ağzı ile İlişkisi
Authors: TULU Sultan
Published: January 2021

On the connection of the Kırcali (Gırcalı) sub-dialect with the dialect of Western Anatolia -based on the data of the present tense suffix of Meninski- Adamovic firstly drew attention. According to the available data, the Western-Anatolian region is not far from the dialects of the middle Deliorman Region. As an example, we can show Edirne-Dağlı dialect, which is located at the dialect of East-Rumelia region. For example: {-(I)vAr(I)} which is shown as an present tense suffix. In this study, on the basis of Kırcali (Kardzhali) Dialect, the connection of Eastern Rumeli Dialect with Western Anatolian Dialect will be compared with certain language criteria and common elements will be revealed.
Türkiye’deki Manihey Harfli Eski Uygurca Neşirler İçin Harfçevrim ve Yazıçevrim Kılavuzu
Authors: UÇAR Erdem
Published: January 2021

Transliteration (< trans + literation) is the spelling of words from one script with characters from the another. Transcription (< trans + scription) is the representation of the sound of words in a language using any set of symbols you may care to invent or borrow for the purpose. The article deals with the characters of transliteration and transcription for editing of Old Uygur texts with the Manichean script in Turkey.
A Note on the Old Turkic Denominal Verb Formative {+GAr-}
Authors: LİM An King
Published: January 2021

Conceptual representation of the Old Turkic denominal verb formative {+GAr-} can be characterized with a schema: “ACT + base noun”. It incorporates the base noun into a verb such that (1) it brings about an action complimentary to the quality, attribute or capacity of the base noun when used without an object; or (2) when used with an object, it brings about an action associating the object with the quality, attribute or capacity of the base noun. The reference to the base noun could be either literal or metonymical. To support the proposition, twenty-two examples were taken from Clauson (1972) and Erdal (1991). Ten among the twenty-two are without an object and twelve with.
Türk Runik Bibliyografyası’na Ek II
Authors: AYDIN Erhan
Published: January 2021

Thousands of studies have been worked on the old Turkic inscriptions, which are the first known written period texts of the Turks, since the first day they were discovered. This article aims to add to the current bibliography published in 2017 as the Turkic Runic Bibliography (İstanbul: Bilge Kültür Sanat Publications). The article contains the overlooked studies in the “Additions” section, and the studies studies in 2019 and 2020 in the “New Publications” section.
Changes in the parameters of nasal breathing and parameters of the upper respiratory tract during orthognathic operations in patients with II and III skeletal class of jaw anomalies
Authors: Gammadaeva S.Sh. , Misirkhanova M.I. , Drobyshev A.Yu.
Published: January 2021

The study analyzed the functional parameters of nasal breathing, linear parameters of the nasal aperture, nasal cavity and nasopharynx, volumetric parameters of the upper airways in patients with II and III skeletal class of jaw anomalies before and after orthognathic surgery.
The respiratory function of the nose was assessed using a rhinomanometric complex.
According to rhinoresistometry data, nasal resistance and hydraulic diameter were assessed.
According to the data of acoustic rhinometry, the minimum cross-sectional area along the internal valve, the minimum cross-sectional area on the head of the inferior turbinate and nasal septum and related parameters were estimated.
According to the CBCT data, the state of the nasal septum, the inferior turbinates, the nasal aperture, the state of the nasal cavity, and the linear values of the upper respiratory tract (nasopharynx) were analyzed.
The patients were divided into 4 groups according to the classification of the patency of the nasal passages by
Designing a bileg silicon-nanowire thermoelectric generator with cavity-free structure
Authors: Mahfuz Md Mehdee Hasan , Tomita Motohiro , Hirao Shuhei , Katayama Kazuaki , Oda Kaito , Matsukawa Takashi , Matsuki Takeo , Watanabe Takanobu
Published: January 2021

Thermoelectric (TE) generators play an important role in preventing an energy crisis and environmental deterioration by converting wasted heat, generated by various human activities, into electrical energy. This work is the first experimental demonstration of a bileg Si-nanowire (Si-NW) micro thermoelectric generator with cavity-free architecture for designing a large-scale integrated planar Si-NW TE generator. In the bileg-TE generator, the mobility and thermopower mismatches between electron and hole effects on the optimum dimensional parameters of n- and p-type Si-NWs and optimum dose of impurity. In this work, under a specific ion dose condition, the best p-type NW width exists at less than 100 nm when the n-type NW width is 60 nm. The experimental dependency of the power density on the p-type NW width is in agreement with the estimation of an equivalent heat-electrical circuit model.
ON current enhancement and variability suppression in tunnel FETs by the isoelectronic trap impurity of beryllium
Authors: Ban Yoshisuke , Kato Kimihiko , Iizuka Shota , Moriyama Satoshi , Ishibashi Koji , Ono Keiji , Mori Takahiro
Published: January 2021

We have experimentally demonstrated ON current enhancement and variability suppression of Si tunnel FETs (TFETs) by introducing an isoelectronic trap (IET) beryllium into the channel. In the previous studies, it was showed that the introduction of the Al-N IET impurity enables those requirements for Si-TFETs. In this study, we focused on Be as a new IET impurity and introduced the new IET into Si-TFETs. We found the optimum conditions for the formation of the Be-IET state in Si and demonstrated process integration of the Be-IET formation and TFET fabrication. The Be-introduced TFET exhibits five times enhancement of ON current; this enhancement ratio is larger than the case of the Al-N IET. Furthermore, significant suppression of the variability is achieved by Be-IET as well as the previous case of the Al-N IET. This better ON current improvement by Be-IET results from the energy level of Be deeper than that of Al-N IET, which plays a better role in enhancing the performance of Si-TFETs.
COVID-19 in Ghana: An Overview of Government Contributions in Fighting this Pandemic
Authors: Evans Yeboah , Kyeremeh Rose Gyamea
Published: January 2021

Coronavirus outbreak has brought significant negative impacts on developed and developing economies with Ghana, not an exemption. This pandemic has slow down economic activities across the globe through unplanned budget expenditures by various government. There is an increasing pressure on many governments to directed tremendous capital resource to stop the outbreak. The perspective of this paper is to provide, update, and inform concerning Covid-19 situation in Ghana, and also look at government expenditure on this pandemic and economic impact. This study employed the quantitative method which promotes the analysis of secondary sources of data. The study captured some of economic and livelihood programme implemented by the government of Ghana to support the most vulnerable persons. With Ghana currently having low active Covid-19 confirmed cases proves that the government has done well to control the spread of the virus.
Financial Literacy on Impulsive Buying Behavior in Y Generation
Authors: Anisa Nur Aini , Arifin Syamsul , Setyowati Lis , Hidayah Nur , Megasari Aisyah Darti
Published: January 2021

Impulse buying is a phenomenon that can occur in all generations but more done by the generation that undergoes a change that is the age of adolescents who step on the early adulthood of the Y generation who actually do not have the financial ability to meet their needs. This study aims to analyze the influence of financial literacy on the impulsive buying behavior of online products in Y generation. This research is a descriptive research type, with a quantitative approach. The population of 733 students. The sampling technique used in this research is nonprobability sampling by using purposive sampling type with sample of 142 students. The subject of this research is the students of university. Data collection technique using questionnaire. Data were analyzed using linear regression analysis. The result of data analysis shows that there is influence of financial literacy on impulse buying behavior of online product in Y generation. It means the higher the student's financial literacy, the lower the impulse buying behavior. Conversely, the lower the student's financial literacy, the higher the impulse buying behavior. Data were analyzed using linear regression analysis. The result of data analysis shows that financial literacy has negative effect, but significant to impulsive buying behavior of online product in Y generation. It means The higher student's financial literacy, the lower impulse buying behavior. Conversely, the lower student's financial literacy, the higher impulse buying behavior.
Analysis of Influence of Compensation and Leadership Style To Employee Performance PT. Feva Indonesia
Authors: Purnamasari Bulawambona Endah , Tridayanti Rr. Hermien
Published: January 2021

The purpose of this study is to study leadership style and comparison of employee performance. This research was conducted at the company PT. Feva Indonesia. The population used was 60 people. Data collection is done through interviews. The analytical tool used is multiple linear regression techniques. The results of the analysis show a positive leadership style but not significant on employee performance. This shows how leadership style is not related or not significant to employee performance, related to employee performance that requires authoritarian support and cannot be involved in the decision making process. Positive and significant compensation variables on employee performance. This shows that fair and proper assistance is needed to be given to employees, the employee's needs will increase significantly.
Train Station Performance Evaluation Based On Minimum Service Standard (Case Study: Cikarang Station, West Java)
Authors: Dermawan Widodo Budi , Fibriyanto Nurul
Published: January 2021

As the population grows and the economic level in the Cikarang area increases the movement of the people. Provision of mass transportation or transportation using the train is very necessary to anticipate the congestion that will occur by providing this train station can be an alternative. Therefore, it is necessary to conduct research to assess the performance and quality of service to to find out how much the level of passenger satisfaction with the service performance of the cikarang station. The method used is the Importance Performance Analysis (IPA) and Chi Square Squares. This study uses 100 respondents for each method. Station performance that does not meet Minimum Service Standards such as waiting rooms, boarding rooms and passenger service facilities. From the analysis obtained the average value of the level of passenger satisfaction with the services and facilities of the Cikarang Station, namely the value of the level of performance with an average weight of 3.17 and the value of satisfaction with an average weight of 3.17, from the highest score of 5 and the lowest score 1. Chi Square Test on the Station Cikarang shows that service factors that significantly influence passenger satisfaction are cleanliness and comfort of the toilet.
Human Resources Management Planning for Increasing Precast Productivity Based on PMBOK at XYZ Company
Authors: Fertilia Novika Candra , Adji Raden Yudityo Afri
Published: January 2021

In the era of globalization, it will demand every company to produce good quality products and also quickly in the completion of the product. Xyz Company is a company engaged in manufacturing. The company produces PCI Girder, Spunpile, U-ditch, and Barrier. But production activities there is a mismatch between the plans and the realization that has been made by the company, especially on spunpile products. The purpose of this study is to find out occurrences that affect human resource management planning and to find out how to manage these occurrences. For the method used, the authors used the method of interviewing, observing and distributing questionnaires. The analysis used is the validity test, reliability test, frequency index, severity index, and importance index. The results of this study are that Xyz company has 4 variables that are most influential in human resource management planning.
The Influence of Job Stress, Job Satisfaction and Work Environment On Organizational Commitment of Keluarga Sehat Clinic Wedoro Sidoarjo
Authors: Diana Safitri Nur , Putra Bayu Airlangga , Arif Mochammad
Published: January 2021

This study aims to determine the effect of work stress, job satisfaction and work environment on keluarga sehat clinic wedoro sidoarjo. This type of research is quantitative, where researchers distribute questionnaires as a medium for data collection and then processed into interval data which is then processed using SPSS18. The population and sample of this study are 36 employees of keluarga sehat clinic wedoro sidoarjo. Hypothesis test results partially work stress partially negative and significant effect on organizational commitment, job satisfaction partially has a positive and significant effect on organizational commitment, and work environment partially does not significantly influence organizational commitment. And the results of the simultaneous hypothesis test was calculated to be 11.570 and included to be greater than Ftable = 2.92. This means that H0 is rejected and H1 is accepted and the significant value is 0,000 less than 0.05. So job stress, job satisfaction and work environment simultaneously have a significant effect on organizational commitment. While the determination test obtained by the coefficient R Square 0.5202 means that the relationship between job stress, job satisfaction and work environment on organizational commitment has an effect of 52.0%, while the remaining 48.0% is explained by other variables not included in the modeling.
PENGARUH VARIASI PELARUT EKSTRAKSI DAN DAYA SIMPAN TERHADAP KADAR ANTOSIANIN DALAM TES KIT UJI FORMALIN BERBAHAN DASAR UBI JALAR UNGU (Ipomoea batatas L. Poir)
Authors: Zuri Rismiarti
Published: January 2021

Formalin merupakan salah satu bahan pencemar kimia yang memberikan efek negatif bagi tubuh. Evaluasi dan monitoring peredaran makanan diperlukan untuk memastikan makanan yang dikonsumsi aman. Tujuan dari penelitian ini adalah pembuatan tes kit uji formalin berbahan dasar ubi jalar ungu untuk memaksimalkan potensi alam dalam rangka membantu mengawasi peredaran makanan berbahaya. Tahapan penelitian yang dilakukan adalah ekstraksi antosianin ubi jalar ungu, optimasi larutan ekstrak antosianin dengan formalin, uji daya simpan, dan uji validasi. Hasil menunjukkan ekstrak dengan pelarut etanol 96% memiliki warna coklat dengan pH 5 dan berwarna merah dengan pH 0 untuk ekstrak menggunakan pelarut etanol 96% dengan HCl 1,5 M. Hasil optimasi larutan ekstrak dengan formalin menunjukkan perubahan warna signifikan dengan perbandingan 1:10 pada ekstrak menggunakan pelarut etanol 96% dan 1:20 untuk ekstrak dengan pelarut etanol 96% dengan HCl 1,5 M. Pengujian daya simpan pada masing–masing pelarut menunjukkan bahwa ekstrak dengan pelarut asam lebih stabil daripada ekstrak yang menggunakan pelarut netral. Hasil uji validasi dapat diketahui bahwa ekstrak antosianin ubi jalar ungu mampu mengidentifikasi adanya kandungan formalin dalam makanan. Hasil perubahan warna signifikan pada pangan yang diuji ditunjukkan pada ekstrak antosianin dengan menggunakan pelarut bersifat asam yaitu etanol 96% dan HCl 1,5 M.
Development of STEM-Based Chemistry Textbooks to Improve Students' Problem Solving Skills
Authors: Hidayatulloh Rohmat , Suyono S. , Azizah Utiya
Published: January 2021

This study aimed to develop STEM-based chemistry textbooks on reaction rate topic, in order to improve students' problem solving skills. Textbooks are developed using the Research & Development (R&D) scheme with feasibility indicators seen from the validity and effectiveness of textbooks. The developed textbook was then tested using a one group pretest-postest design research, where the research subjects were 30 students of class XI at SMA Wachid Hasyim 1 Surabaya. The research data were obtained from expert validation sheets and student problem solving skills test sheets. Based on the research conducted, it was found that 1) the textbook developed had a validity score of 3.70 and was categorized as very valid, 2) the increase in student problem solving skills classically obtained was 0.75, in the high category, 3) the percentage of completeness a test of student problem solving skills by 90%, so that STEM-based textbooks can be state to be effective in improving students' problem solving skills. Based on these results, it can be conclude that STEM-based textbooks developed feasible to improve students' problem solving skills.
Peningkatan Kapasitas Guru Sekolah Piloting dalam Lesson Study for Learning Community di SMP Muhammadiyah 1 Malang
Authors: Miharja Fuad Jaya , Husamah Husamah , Masrudi Masrudi
Published: January 2021

Program pendampingan Lesson Study for Learning Community (LSLC) di Sekolah Muhammadiyah telah memasuki tahun ketiga dan terus dilakukan penyempurnaan program. Dalam pelaksanaannya ketersediaan dokumentasi pembelajaran masih menjadi tantangan yang perlu diselesaikan, karena ketersediaan dokumentasi empiric merupakan aspek fundamental dalam melakukan refleksi dan rencana tindaklanjut. Pendampingan dilaksanakan selama bulan Maret – Juli 2020 di SMP Muhammadiyah 1 Malang. Metode pelaksanaan yang mengacu kepada analisis situasi program-program yang disepakati bersama dengan pihak sekolah adalah diskusi penyamaan persepsi, lokakarya, pendampingan, dan monitoring evaluasi. Kegiatan pendampingan telah menginisiasi guru dalam memaknai LSLC sebagai komunitas belajar dan memahami teknik dasar pelaksanaan observasi secara komprehensif
Sosialisasi Pencegahan Demam Berdarah Dengue (DBD) Melalui Pelatihan Pembuatan Ovitrap Pada Masa Pandemi di SMP Muhammadiyah 1 Malang
Authors: Roziqin Ali , Nuryady Mohammad Mirza , Fauzi Ahmad , Setyaningrum Yanur
Published: January 2021

Kota Malang menjadi salah satu daerah endemis yang memiliki insiden DBD yang cukup tinggi. Disisi lain, efek pandemic covid-19 yang mengharuskan masyarakat lebih banyak melakukan aktivitas di rumah, memungkinkan jumlah infeksi DBD akan meningkat sehingga perlu upaya penanggulangan. Peran masyarakat dalam penurunan angka kejadian DBD sangat vital, karena pemberantasan DBD yang paling efektif yaitu dengan memutus siklus hidup nyamuk. Salah satu cara untuk memutus siklus hidup nyamuk adalah dengan membuat perangkap telur nyamuk (Ovitrap). Pada era pandemik aktivitas sosialisasi tidak dapat dilakukan secara massive, dalam hal ini guru memiliki peran kunci untuk menyebar luaskan informasi kepada siswa tentang prilaku hidup bersih (PHBS) guna menanggulangi DBD. Sosialisasi ini bertujuan untuk meningkatkan pemahaman guru tentang penyakit DBD, cara penanggulangan, cara pembuatan ovitrap, dan meningkatkan kesadaran guru untuk berpartisipasi dalam mengingatkan siswa untuk selalu menjaga melakukan PHBS seperti pemberantasan sarang nyamuk dengan metode 3M Plus. Metode yang dilakukan untuk mengatasi masalah tersebut adalah melalui kegiatan sosialisasi pencegahan DBD dan pembuatan ovitrap. Bertempat di aula SMP Muhammadiyah 1 Malang dilaksanakan penyuluhan tentang penyakit DBD. Respon positif dan antusiasme guru terhadap pelaksanaan sosialisasi ditunjukkan dari rata-rata pengetahuan guru tentang DBD yang baik.
EFEKTIVITAS PENERAPAN INTERNET MARKETING 4.0 TERHADAP PEMESANAN TIKET TRAVEL PEKANBARU DURI DUMAI
Authors: Azim Fauzan , Akhmad Ikhbal , Purwanto Hadi , Anshari Khairul , Sunanto Sunanto
Published: January 2021

Penelitian ini dilaksanakan di PT. Jasa Mulya Trans Gemilang, perusahaan yang bergerak dibidang layanan jasa transportasi antar jemput alamat dengan rute pekanbaru duri dumai. PT. Jasa Mulya Trans Gemilang memiliki dua buah website yang cukup baik di search engine Google, Bing dan Yahoo. PT. Jasa Mulya Trans Gemilang juga melakukan Promosi Iklan melalui Media Sosial dan Iklan Berbayar Google Ads yang sudah berjalan cukup lama.  Dan sampai saat penelitian ini dilakukan belum ada pengukuran seberapa baik tingkat Efektivitas Internet Marketing yang telah berjalan di PT. Jasa Mulya Trans Gemilang. Pengukuran Efektivitas Sebuah Program Internet Marketing sangat diperlukan untuk bahan pertimbangan dan strategi promosi yang dapat dilakukan untuk kedepanya oleh perusahaan. Dan untuk mengukur sebuah Efektivitas Pemanfaatan Internet Marketing salah satunya dapat memanfaatkan Model EPIC. Pada Model EPIC terdapat empat Variabel yang diteliti untuk mengukur efektivitas yaitu Empathy, Persuasion, Impact dan Communication. Responden dalam penelitian ini adalah masyarakat kota Pekanbaru dan sekitarnya yang memesan tiket travel dengan tujuan daerah Duri sekitarnya, dan Kota Dumai. Setelah dilaksanakan penelitian ini maka didapatkan hasil yang membuktikan bahwa tingkat efektivitas Penerapan Internet Marketing terhadap pemesanan tiket travel Pekanbaru Duri Dumai yang diukur dalam  empat Dimensi EPIC yang masing-masing bernilai sebagai berikut; emphaty bernilai 4,09, persuasion bernilai 4,11, impact bernilai 3,88, dan communication bernilai 3,99. Dari keempat Dimensi EPIC tersebut maka didapatkan hasil rata-rata Model EPIC atau EPICrate 4,02 yang dapat di interpretasikan pada skala efektif, Artinya dalam penelitian ini, Penerepaan Internet Marketing di PT. Jasa Mulya Trans Gemilang melalui internet yang terdiri dari Website, Media Sosial dan Google Ads dapat dinyatakan Efektif.
APLIKASI PEMBELIAN DAN PELAYANAN SERVICE COMPUTER (CV BARA OGAN DHIEVA) BERBASIS WEB DAN ANDROID
Authors: Prabudi Ari , Awaludin Azmil , Prasetia Raka Andika , Ismawati Nur
Published: January 2021

Dalam penjualan dan pelayanan jasa service CV Bara Ogan Dhieva  konsumen harus datang langsung ke toko fisik untuk dilakukan pengecekan oleh teknisi[1]. Apalagi dimasa pandemi covid ini dimana masyarat dianjurkan oleh pemerintah untuk tidak terlalu sering keluar rumah. Penelitian ini bertujuan membuat aplikasi yang membantu konsumen CV Bara Ogan Dhieva agar dapat berbelanja dan melakukan pemesanan jasa service komputer secara flexible[2]. Adapun metode yang digunakan dalam penelitian pembuatan aplikasi ini yaitu metode waterfall, hasil dari aplikasi ini membuat proses transaksi dalam pembelian ataupun pemesanan jasa service komputer di CV Bara Ogan Dhieva lebih efektif dan tersistematis dengan baik.
Analysis of bactericidal effects of sodium hypochlorite and chlorhexidine on resistantbiofilm microorganisms (E. Faecalis, C. Albicans).
Authors: Khabadze Z. S. , Generalova Yu. A. , Shubaeva V. S. , Ismailov F. R. , Sheroziia M. G. , Nedashkovsky A. A. , Negorelova Ya. A.
Published: January 2021

Aim. To analyze current data on the bactericidal efficacy of endodontic irrigants, in particular, sodium hypochlorite and chlorhexidine in different concentrations relative to the elimination of resistant microorganisms (E. Faecalis, C. Albicans). Irrigation is an important stage in the treatment of root canals, it prevents the further contamination of the canals with microorganisms. However, irrigants do not always cope with this function, which leads to the occurrence of a secondary infection.Materials and methods. The study of publications was produced in the electronic databases such as Google Scholar, PubMed and ScienceDirect in the course of a systematic review of the literature. Included articles contain information about various types of irrigants and their antimicrobial effect.Results. 73 articles were viewed during the review. After analyzing the literature for inclusion criteria, the total number of publications has become 41.Conclusions. According to literature data, irrigation solutions in widely used by clinicians concentrations (sodium hypochlorite 3%, chlorhexidine 2%) are not able to completely eliminate E. faecalis and C. albicans from the root canal system.
Experimental research of retreatability of root canals filled with bioceramic sealer
Authors: Mitronin A. V. , Ostanina D. A. , Mitronin Yu. A.
Published: January 2021

Aim. This study aimed to determine the residual filling material and the reestablishment of working length and apical patency after retreatment of TotalFill® BC Sealer.Materials and methods. Thirty maxillary incisors were used in a single cone obturation technique with TotalFill BC Sealer (FKG, Switzerland) and randomly divided into 6 groups according to the retreatment technique. The samples were scanned by micro-CT before and after retreatment in order to evaluate the residual filling material on the root dentin walls. Data were analyzed statistically with the Kruskal-Wallis tests (p < 0.05).Results. No instrumental protocol was able to remove all obturation material from the root canals. The differences in reduction in the total volume of filling material percentage were statistically significant (p < 0.05) among groups with and without ultrasound or sound activation in retreatment protocol.Conclusions. The most effective root canal retreatment was determined with D-Race + XP-endo Shaper + XP-Endo Finisher R + US (3.0 W) protocol; it was found that the efficiency of filling material removal was more than 92%.
السذاجة وعلاقتها بالذكاء الاجتماعي لدى طلبة الجامعة
Authors: تركي نافل القريشي أ.م.د. علي
Published: January 2021

استهدف البحث دراسة السذاجة (Gullibility) وعلاقتها بالذكاء الاجتماعي Social Intelligence) ) لدى طلبة الجامعة , والسذاجة هي النزعة لأن يكون الانسان محذراً او متلاعباً به بواسطة واحدة أو أكثر من الوسائل الخادعة للناس الآخرين , والذكاء الاجتماعي ذلك النوع من الذكاء الذي يتوسله الفرد في معاملاته مع الآخرين من الناس , وفي ممارسته العلاقات الاجتماعية . وقد تم بناء مقياس السذاجة على وفق المنظور المعرفي الذي ضم معظم نظريات السذاجة التي تم استعراضها في فصل الاطار النظري . أما لقياس الذكاء الاجتماعي فقد تم تبني مقياس أبو عمشة ( 2013) . وقد أجريت على المقياسين الخطوات الآتية : الصدق الظاهري , التمييز, الاتساق الداخلي (علاقة الفقرة بالمجموع الكلي ) , الصدق التمييزي , الثبات بطريقة ألفا كرونباخ . وأظهرت النتائج مايأتي , ان طلبة  الجامعة لايتمتعون بمستوى عال من السذاجة , أي أنه موجود بشكل معتدل . وليس هناك فرق دال في السذاجة بحسب التخصص , وأيضا ليس هناك فرق بحسب الجنس  . كما ان طلبة  الجامعة يتمتعون بمستوى عال من الذكاء الاجتماعي . وليس هناك فرق دال في الذكاء الاجتماعي بحسب التخصص أو الجنس ,. أما العلاقة فقد كانت ضعيفة بين السذاجة والذكاء الاجتماعي  لدى عينة البحث . وخرج البحث بكثيرٍ من التوصيات والمقترحات .