bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing a Health Game to Prepare Preschool Children for Anesthesia: Formative Study Using a Child-Centered Approach (Preprint)
Authors: Ingadottir Brynja , Laitonen Elina , Stefansdottir Adalheidur , Sigurdardottir Anna Olafia , Brynjolfsdottir Berglind , Parisod Heidi , Nyman Johanna , Gunnarsdottir Karitas , Jónsdóttir Katrín , Salanterä Sanna , Pakarinen Anni
Published: July 2021

BACKGROUND

Every year, millions of children undergo medical procedures that require anesthesia. Fear and anxiety are common among young children undergoing such procedures and can interfere with the child’s recovery and well-being. Relaxation, distraction, and education are methods that can be used to prepare children and help them cope with fear and anxiety, and serious games may be a suitable medium for these purposes. User-centered design emphasizes the involvement of end users during the development and testing of products, but involving young, preschool children may be challenging.

OBJECTIVE

One objective of this study was to describe the development and usability of a computer-based educational health game intended for preschool children to prepare them for upcoming anesthesia. A further objective was to describe the lessons learned from using a child-centered approach with the young target group.

METHODS

A formative mixed methods child (user)-centered study design was used to develop and test the usability of the game. Preschool children (4-6 years old) informed the game design through playful workshops (n=26), and usability testing was conducted through game-playing and interviews (n=16). Data were collected in Iceland and Finland with video-recorded direct observation and interviews, as well as children’s drawings, and analyzed with content analysis and descriptive statistics.

RESULTS

The children shared their knowledge and ideas about hospitals, different emotions, and their preferences concerning game elements. Testing revealed the high usability of the game and provided important information that was used to modify the game before publishing and that will be used in its further development.

CONCLUSIONS

Preschool children can inform game design through playful workshops about health-related subjects that they are not necessarily familiar with but that are relevant for them. The game’s usability was improved with the participation of the target group, and the game is now ready for clinical testing.
Gerontologija
Authors: Sekulic Bojana
Published: July 2021

Prikaz knjige:
Zoran Vesić Gerontologija Fakultet
političkih nauka, Univerzitet u Beogradu,
Beograd 2021, str. 230
Dual band T Shaped Antenna at Millimeter Wave Frequency for 5G Applications
Authors: Mishra Prishail
Published: July 2021

In this paper, there is a t shaped antenna patch on a 12mm X 12mm plane, with another patch which is inverted T shaped patch on the same plane. Its operated in the frequency range of 24GHz to 40GHz. It is a millimeter wave frequency antenna for 5th generation applications. Owing to its compact size it has less complexity, and fed by waveguide on both sides of patch[1]. It gives a bandwidth of 2GHz and 5.6 GHz in the range 24-26 GHz and 30-35GHz respectively. Radiation efficiency is of 83% at 40 GHz and directivity of 5.27 . We get to see two resonating frequencies, one at 28GHz and other at 37 GHz thus creating dual band antenna[2].
Application of Machine Learning for Emotion Classification
Authors: Babhulkar Mr. Shubham
Published: July 2021

In this paper we propose an implement a general convolutional neural network (CNN) building framework for designing real-time CNNs. We validate our models by creat- ing a real-time vision system which accomplishes the tasks of face detection, gender classification and emotion classification simultaneously in one blended step using our proposed CNN architecture. After presenting the details of the training pro- cedure setup we proceed to evaluate on standard benchmark sets. We report accuracies of 96% in the IMDB gender dataset and 66% in the FER-2013 emotion dataset. Along with this we also introduced the very recent real-time enabled guided back- propagation visualization technique. Guided back-propagation uncovers the dynamics of the weight changes and evaluates the learned features. We argue that the careful implementation of modern CNN architectures, the use of the current regu- larization methods and the visualization of previously hidden features are necessary in order to reduce the gap between slow performances and real-time architectures. Our system has been validated by its deployment on a Care-O-bot 3 robot used during RoboCup@Home competitions. All our code, demos and pre- trained architectures have been released under an open-source license in our public repository.
Cloud based EDoS Attack Prevention System Using Dual Access Control Mechanism
Authors: Deulkar Deepa S.
Published: July 2021

Cloud based data storage is becoming very popular nowadays as one can easily download any document from anytime and anywhere. However documents security is very important in cloud storage as cloud is a third party server which can be accessed by administrators. There are many literatures available to improve document security on cloud and most of the literatures proposed various data encryption techniques. However, simply encrypting data (e.g., via AES) cannot fully address the practical need of data management. Besides, an effective access control over download request also needs to be considered so that Economic Denial of Sustainability (EDoS) attacks cannot be launched to hinder users from enjoying service. In this project, we consider the dual access control, in the context of cloud-based storage, in the sense that we design a control mechanism over both data access and download request without loss of security and efficiency. Along with dual access control we also focus on document security by using modified AES algorithm.
Future Expectations of Sovereign Vehicles
Authors: Srivastava Ayush
Published: July 2021

Sovereign vehicles are the smart vehicles of this upcoming era, expected to be driverless, competent, and collision free vehicles. To achieve this aim, automakers have begun to work in this area to understand the depth and overcome the present hurdles in order to achieve the desired end. The first challenge in this strategy would be to absorb current practices in conventional vehicles in order to transfer them to self-driving vehicles through the adoption and implementation of several emerging technologies. This encompasses the goals of autonomous vehicles as well as the challenges of implementing them. The existing Automated vehicles (AVs) controversy isn't about whether or not they should be employed; they're currently in use. Rather, such worries are increasingly focused on how developing technology will impact evolving transportation networks, our social environment, and the people who live in it, as well as whether such systems should be completely automated or remain under human control. This research adds to the body of knowledge by attempting to shed light on future prospects as well as potential roadblocks linked with AV technology. We want to address these concerns and offer some solutions to the difficulties that are currently surfacing.
Design and Implement an App for Renting Property
Authors: Dwivedi Shivendra
Published: July 2021

Nowadays, there is an online rental system curated for things like furniture, car, house etc. which benefits the user. A rental service is a service in which customers arrive to request the hiring of the rental unit. It is more convenient than carrying the cost of owning and maintaining the unit. In this paper we are introducing an Application – The purpose of the project is to reduce the human effort and automate the existing manual method into an application. This application is based on the owner, customer and administrator. Owner and customer both are the main users of this app. Customers already know everything about the rooms by app because they have already seen pictures of the room and are also familiar with the features. It is an extended form of giving out things often organized with numerous local branches and complemented by an application allowing online reservation.
Online Examination Portal
Authors: Pandey Shailja
Published: July 2021

The aforementioned portal of Online Examination Portal is being featured in the document that will include all characteristics and procedures which are required. This document include acute details about objectives of the structure, portal scope restraint, portal action model, primary structure requirements, team burgeoning, probable devise perils, schedule of the inventory, and eventually surveying and divulging mechanisms for the entire portal structure. Online Examination Conducting Portal is very beneficial for Educational Institute's to formulate an entire exam, saving time to check the papers and concoct mark sheets. Online Examination Portal will help the Educational Institute to scrutinize students capabilities and develop their adroitness. But the flaws for Online Examination portal occur it takes excessive time when user formulates the exam for the first time. And to take the exam we prefer the same tally of set- ups as the number of students. The potent use of Online Examination Portal, the coordinator can use this portal to formulate the tests as their necessity, and for getting better results in less time.
Abstract Algebra
Authors: Sharma Vibhuti
Published: July 2021

Ring hypothesis is one of the pieces of the theoretical polynomial math that has been thoroughly used in pictures. Nevertheless, ring hypothesis has not been associated with picture division. In this paper, we propose another rundown of similarity among pictures using rings and the entropy work. This new record was associated as another stopping standard to the Mean Shift Iterative Calculation with the goal to accomplish a predominant division. An examination on the execution of the calculation with this new ending standard is finished. In spite of the fact that ring hypothesis and class hypothesis from the start sought after assorted direction it turned out during the 1970s – that the investigation of functor groupings furthermore reveals new plots for module hypothesis.
Design and Implementation of Effective Digital Photo Frame
Authors: More Prof. Chetan S
Published: July 2021

Digital picture frames are nice because they let us enjoy our photos without having to print them out. Plus, adding and removing digital files is a lot easier than opening a traditional frame and swapping the picture inside when you want to display a new photo. In this paper, we are going to implement Digital Photo Frame using Raspberry Pi,
Management of Smart Grids: A Review
Authors: Singh Kshitij
Published: July 2021

Electrical power grid has witnessed continuous changes over the past century but phenomenal developments are visible in the last two decades or so. The demand of 24x7x365 power supply, and development in socio-economic status of individuals and nations the demand of electrical power hence grid complexity is rising. Moreover shifting to renewables has opened a whole new can of worms. The conventional approach of grid management is unable to cater the needs of such a complex demand and supply needs. The present work is an approach addressing various modalities, modes of operation and management of smart grids. This includes demand side management in household and non-household scenarios, ICT and cyber security concerns.
Bank Locker Security System Using IoT
Authors: Sulthana Shazia
Published: July 2021

Every person has precious accessories such as gold, jeweleries or in terms of cash. To prevent it from any mishandling. We keep it in a locker system of bank concern with it likewise in old way system of a bank there was a private key system which is associated with the concern user and every time he or she has headache to carry key with him or has keep burden of key lost or key duplication problem.so to overcome above major drawbacks the recent system of biometrics is introduced. It is very advance as compared to any traditional system. This system comes with the feature of face detection which provides more security.
Smart Parking System
Authors: Bharathi V. C.
Published: July 2021

In the modern age, many people have vehicles. Vehicle is now a primary need. Every place is under process of urbanization. There are many supermarkets and shopping centers etc. There are many creative places where people used to go for refreshing and relaxation. All these places are full of with people so they need a parking space where people can park their vehicles safely and easily. Every parking area needs a website or system that records the detail of vehicles to give the parking facility. With the help of iot based system we can deliver a good service to users/people who wants to park their vehicles into organization’s premises. Present days in parking areas they just maintain the vehicles just with tokens and they have records of vehicle details in books so that during some critical situations like police enquiry of terrorist car or vehicle missing that case it is difficult to find the details of particular vehicle. But with our parking management system it is easy to find within 1 to 2 seconds. By parking the vehicle in public place the vehicle can be claimed by other person but in this case there is no such problem and no need to give fine for anything we can park our vehicle with securely.
Smart Security System Using Image Recognition
Authors: Hegde Arpita Prakash
Published: July 2021

The Smart Security System using Image Recognition uses Deep Learning and Computer Vision approach.In real time it would help the home based security system to track the persons coming into the house and unlocking the door, hereby the system would be accessed by using the image recognition service in which the images are trained in different classes labeled with the names of the family members and not only them they can train the images of their relatives which provides the access to unlock their door. By using this model one can secure the home premises from the invaders and also capture the suspected people who are not authorized to move inside the house. By using “dlib one short learning”, all the faces for permission would be trained and the model is given to the security system where it can secure the premises with good accuracy through trained images.
Review Paper on Town Planning
Authors: Jangir Gourve
Published: July 2021

Town making plans is regularly visible as an tool of social reform. It is argued right here that this becomes now no longer the case beneathneath social democracy, and with the aid of using implication neo-liberalism and globalization do now no longer always act as brakes upon reform. Planning need to be interpreted in magnificence terms, as a method of stabilization and legitimation thereby supporting to make sure boom. It fragments social truth if you want to include the political actions that city troubles may want to generate. This view of making plans can also additionally provide an explanation for why social reform isn't excessive on making plans's agenda. But social reform is viable however handiest at instances of excessive conflict. For making plans to take gain of such temporary opportunities, making plans concept desires development. The puper concludes with the aid of using growing a version of social reform and searching at a number of the flashpoints that might cause it.citites and metropolis ten to develop in an unplannned way with passage of time while and insial plan has been accepted. the awareness of sports has accumulated in and round big and medium sattelment the metropolis are extra then the municipal limits,they have got extanded to the agglomeration as a result the real limt of the metropolis have extra then doubled if you want to manage unplanned boom og cities.there for it required regular become over every and each assume associated with scheme. the artical address publical isssue of metropolis making plans layout of agricultural cluster in a huge metropolis as an intigeral a part of designning mathodology for sustainable devlopment of toen making plans.the precept of intigrating land scape agro-land scape and housing devlopment ,the precept of bio effective layout of buldins and complexes,
Compare the Symmetric Hybridized Cascaded MLI with 17 levels with the Asymmetric Switched Capacitor MLI Topologies for Dynamic Loading
Authors: Patil Jayesh B.
Published: July 2021

This article builds a symmetric hybridized cascaded a switching capacitor unit in a multilayer inverter and compares it to For 17 level inverters, A switched capacitor unit is utilized with an asymmetric multilevel inverter. In the symmetric hybridized multilevel inverter design, a In the midst of a dual-input dc source, there is a bi-directional switch is utilized to create a modified H-bridge inverter with a five-level output voltage instead of three. In the proposed scenario, In an asymmetric multilevel inverter, the switched capacitor unit substitutes the dc sources. which enlarges By a factor of two, The output voltage has been increased. and the voltage levels at the loads are increased by a factor of two. MATLAB-SIMULINK was used to verify the suggested topology using the staircase modulation approach. The findings show that multilayer inverter topologies with low total harmonic distortion, fewer switches, With greater levels of output voltage are better stable during load disturbance circumstances, making them ideal for renewable energy applications.
Software Defined Radio in Radio Frequency Identification Applications
Authors: Rani Supriya
Published: July 2021

RFID is an important aspect of today's age because it boosts efficiency and convenience. It is used for a lot of applications that prevent thefts of automobiles and merchandise. In current times there have been continuous transitions from analog to digital systems where software is being used to define the waveforms and analog signal processing is being replaced with digital signal processing. In this paper, we have done a thorough literature survey and understood the working of how software-defined radio is implemented in radio frequency identification for a better BER performance.
Energy and Depression Management System
Authors: Soni Gaurav
Published: July 2021

The aim of the Internet of things (IoT) is to bring every object online. These different objects generate huge data which consequently lead to the need of requirements of efficient storage and processing. Cloud computing is an emerging technology to overcome this problem. The pandemic due to COVID-19 has caused great impact on people’s approach to have proper lifestyle. People these days are found inactive, unhappy and less energetic, because of their busy routine and continual ignorance of overall health. By keeping a track of their mental and physical health, one could achieve better response and hence expected lifestyle. Our solution is to detect, analyze and deliver a solution to treat depression and assist people with fulfilling their daily energy requirement for being more active and enthusiastic. Our solution is a Soft-Ui Web Application that gives smooth UI/UX experience to users showcasing fluctuations in energy and playing games to get cognitive features’ result. The hardware is a wearable wrist band made with NodeMCU embedded with accelerometer and heart rate sensors. An analytical report is generated and updated in real time and user could download as per their convenience.
On Kitab Patanjali by Al-Biruni. Introductory article to the translation
Authors: Pskhu R. V.
Published: July 2021

The interaction of various religious and philosophical traditions in the epistemological, soteriological and ontological levels is one of the most interesting topics of the modern culture. And in this sense, the text of Bīrūnī is more relevant today than ever, because it demonstrates the feasibility of one of the most problematic types of interaction — the Islamic tradition and the Hindu tradition. The paper deals with the sample of such an interaction in the period of the Middle Ages. The paper represents a brief introduction to the ﬁrst Russian translation of some fragments of the Arabic text “Kitāb Bātanjali al-Hindī” by Abū Rayḥān Muḥammad ibn Aḥmad al-Bīrūnī.
POTENSI BEBERAPA JENIS RUMPUT LAUT DI ACEH (STUDI KASUS: SKRINING FITOKIMIA DAN AKTIVITAS ANTIOKSIDAN)
Authors: Mayasri Adean
Published: July 2021

One of the sea potentials in Aceh is seaweed. Seaweed contains secondary metabolites and antioxidants that are very well consumed because it can act as an antidote/protector from the free radicals. This study aimed to determine the secondary metabolite content and antioxidant activity of seaweed in Aceh.The seaweed that has been macerated then screened for phytochemicals and tested for antioxidant activity by using the DPPH method. The seaweed species found were Gracillaria verrucosa, Sargassum sp., and Chaetomorpha antennina. The results of this study indicated that Gracillaria verrucosa, Sargassum sp., and Chaetomorpha antennina seaweeds were contained by alkaloids and steroids. Flavonoid and saponins were only detected in the types of seaweed Gracillaria verrucosa and Sargassum sp. It was also found that the higher the concentration of the extract, the higher the percentage of IC50 against free radicals. The Sargassum sp. has a stable percentage of inhibition at a 2-10 ppm concentration, so it is recommended in this study to be considered cultivated in Aceh.
Past, Present and Future of the Neoinstitutional Approach in Political Science
Authors: Matveev A. A.
Published: July 2021

The article describes the stages of formation and evolution of the neo-institutional approach. A brief description is given of the main directions that arose within the framework of the non-institutional theoretical direction. Based on the comparative characteristics of neoinstitutional approaches, trends in modern neo-institutionalism are deduced. The author concludes that the formation of neo-institutionalism has not been completed, and describes promising directions for its further development.
Strategic Directions of Innovative and Economic Development of the Pskov Region
Authors: Miroslavskaya M. V. , Kozyrev A. A.
Published: July 2021

The modern development of the economy of the Russian Federation is characterized by an imbalance in the socio-economic development of the regions, which is due to the increased interregional competition, uneven resource provision, investment history, etc. Regions are components of the unified socio-economic and political system of Russia, but each of them has its specifics. Among the factors that determine the specifics of the region stand out: historical, climatic, national, social, and economic. Taking into account all these factors, the choice of means and methods of effective management of the socio-economic system of the region should be made to ensure its sustainable long-term development and functioning. In recent years, under the influence of a qualitatively different level of development of the productive forces, the introduction of innovations in all spheres of life, IT and telecommunication systems, as well as the development of network forms of organizing production, the problem has taken on new forms.
Analisis Kandungan Zat Gizi Tepung Tulang Ikan Sidat (Anguila sp)
Authors: Ahmil Ahmil , Muliyati Hepti , Mananta Opyn
Published: July 2021

Pemanfaatan limbah tulang ikan salah satunya adalah dibuat tepung. Pengolahan dalam bentuk tepung bertujuan untuk memperpanjang daya awet dan daya simpan. Tepung ikan dapat ditambahkan pada produk ekstrusi, roti, biskuit dan kue kering. Namun pemanfaat tepung tulang ikan sidat menjadi bahan pangan masih sangat kurang. Oleh karena itu, perlunya dilakukan penelitian pendahuluan terkait analisis kandungan gizi pada tepung tulang ikan sidat tersebut. Penelitian ini dilakukan dalam dua tahapan, yaitu tahap pembuatan tepung dan tahap analisis zat gizi. Analisis zat gizi dilakukan di Laboratorium Saraswanti Indo Genetech (SIG) Bogor meliputi Kadar abu dianalisis dengan metode SNI 01-2891-1992, 6.1; kadar air dianalisis dengan metode SNI 01-2891-1992, poin 5.1;  protein dianalisis dengan metode 18-8-31/MU/SMM-SIG (Kjeltec); lemak total dianalisis dengan metode 18-8-5/MU/SMM-SIG (Weilbull); energi dari lemak dianalisis dengan metode kalkulasi; energi total dianalisis dengan metode kalkulasi;  karbohidrat dianalisis dengan metode 18-8-9/MU/SMM-SIG; Besi dianalisis dengan metode 18-13-1/MU/SMM-SIG (ICP OES), Seng dianalisis dengan metode 18-13-1/MU/SMM-SIG (ICP OES); Kalsium dianalisis dengan metode 18-13-1/MU/SMM-SIG (ICP OES). Hasil penelitian menunjukkan bahwa tepung tulan ikan sidat menandung kadar abu 44.14%, kadar air 5.98%, protein 34.08%, lemak total 9.14%, karbohidrat 6.66%, besi 20.45 mg/100 g, seng 10.34 mg/100 g, dan kalsium 18325.13 mg/100 g.  Kesimpulannya tepung tulang ikan sidat mengandung kadar abu, protein, dan kalsium yang sangat tinggi dibandingkan zat gizi lainnya.
Sistem Penyelenggaraan Makanan, Preferensi Menu dan Tingkat Kepuasan di PPLP Jawa Barat
Authors: Putra Aditya Sagara , Ronitawati Putri , Sitoayu Laras , Nuzrina Rachmanida , Melani Vitria
Published: July 2021

Preferensi konsumen menggambarkan suatu kecenderungan perilaku konsumen pada pola konsumsi dan daya tarik mereka terhadap nilai-nilai yang disediakan oleh pihak penyelenggara makanan. Penelitian ini bertujuan untuk mengetahui analisa penyelenggaraan makanan, hubungan preferensi menu dengan tingkat kepuasan makanan di Pusat Pendidikan Latihan Pelajar (PPLP) Jawa Barat. Jenis penelitian ini adalah penelitian Cross Sectional dengan metode survey observational. Sampel sebanyak 81 responden dengan menggunakan teknik pengambilan sampel purposive sampling. Analisa statistik menggunakan Uji Korelasi Pearson. Penelitan ini menunjukkan bahwa preferensi menu memiliki hubungan dengan tingkat kepuasan makanan (p=0.000), tidak ada hubungan antara variasi menu dengan tingkat kepuasan makanan (p=0.630), penampilan makanan memiliki hubungan dengan tingkat kepuasan makanan (p=0.000), dan rasa makanan memiliki hubungan dengan tingkat kepuasan makanan (p=0.000). Semakin pihak institusi memperhatikan preferensi menu atlet, maka atlet akan merasa puas dengan penyelenggaraan makanan yang disediakan institusi
Edukasi Media Tote Bag Merubah Pengetahuan Serta Sikap Kader Posbindu Dalam Pengukuran Antropometri Dan Gizi Seimbang Lansia
Authors: Subagyo Sarah Ameilia , Sitoayu Laras , Jus’at Idrus , Gifari Nazhif , Harna Harna
Published: July 2021

Kader posyandu lansia (Posbindu) mempunyai peranan penting dalam kegiatan Posbindu. Beberapa tugas kader adalah mengukur tinggi dan berat badan lanjut usia (lansia) juga memberikan edukasi mengenai gizi seimbang untuk lanjut usia (lansia), akan tetapi kader belum melakukan pengukuran tinggi badan serta berat badan dengan tepat. Tujuan penelitian ini untuk mengetahui apakah pemberian media tote bag dapat mempengaruhi perubahan pengetahuan serta sikap kader posbindu dalam pengukuran antropometri dan gizi seimbang pada lansia. Desain penelitian memakai metode Quasi Eksperiment dengan desain one group pre-test dan post-test pada 35 responden kader Posbindu di wilayah Pondok Kacang Timur, Pondok Aren, Tangerang Selatan. Mengukur perubahan pengetahuan serta sikap menggunakan kuesioner pre-post test. Uji analisis bivariat yang di gunakan adalah Uji Paired Sample T-test untuk data yang berdistribusi normal dan Uji Wilcoxon untuk data yang berdistribusi tidak normal. Hasil penelitian menunjukkan bahwa ada perubahan rata-rata nilai pengetahuan dan sikap kader Posbindu dalam pengukuran antropometri dan gizi seimbang pada lansia dibandingkan sebelum dan sesudah intervensi. Pemberian edukasi dengan media tote bag dapat merubah pengetahuan serta sikap kader Posbindu dalam pengukuran antropometri dan gizi seimbang pada lansia
DOES THE USE OF DEXMEDETOMIDINE AFFECT THE OUTCOMES IN PATIENTS WITH SEVERE COVID-19?
Authors: İşsever Kubilay , Genç Ahmed Cihad , Çekiç Deniz , Genc Ahmed Bilal , Yaylaci Selcuk , NALBANT AHMET
Published: July 2021

Objective: Dexmedetomidine (DEX) is a highly selective α2-adrenoceptor
agonist that is increasingly used in the daily practice of intensive
care units (ICUs) with its sedative, analgesic, anxiolytic, and
immunoprotective effects. In this study, we aimed to analyze whether
Dexmedetomidine improves the outcomes in patients treated in ICU.
Design: A retrospective study Place and Duration of Study: Intensive
care units (ICU) of Sakarya University Training and Research Hospital,
Sakarya, Turkey, from October 2020 to February 2021 Methodology: The
medical records of the patients were analyzed retrospectively. We
included 134 patients in the study, in 45 of whom the treatment regimen
included dexmedetomidine and 89 of whom were not treated with
dexmedetomidine. Patients treated with DEX were defined as the “patient
group”, whereas patients not treated with DEX were defined as “control
group” and the parameters were compared between these groups. Obtained
data were analyzed in the biostatistical program. Results: The median
age of all patients was 64 and 62.7% of them were male. No significant
difference was found between the groups in terms of median ages
(p>0.05). The patients with diabetes mellitus (DM),
congestive heart failure (CHF), and undergoing insulin treatment were
significantly less treated with DEX (p=0.04, p=0.03, and p=0.016
respectively) whereas intravenous immunoglobulin (IVIG) therapy was
found to be more frequently applied to the patient group (p=0.043). The
median duration between ICU admission and the time of intubation was 4
days for the control group whereas it was 1 day for the patient group
and the difference was strongly significant (p=0.000,
p<0.001). The other analyses concerning lab parameters,
mortality rates, intubation rates and durations, applied treatments, and
comorbidities revealed no significant difference between the groups.
Conclusion: Our study revealed that DEX therapy can help us to gain time
before intubation however can not reduce mortality rates in severe
COVID-19.
NLRP3 activation contributes to Endothelin-1-induced erectile dysfunction
Authors: Fais Rafael , Costa Rafael Menezes da , Mendes Allan Carvalho , Mestriner Fabiola Antunes Cardoso , Comerma-Steffensen Simon , Tostes Rita , Simonsen Ulf , Carneiro Fernando
Published: July 2021

Background and Purpose: Endothelin-1 (ET-1) and Nucleotide
Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3
(NLRP3) play an essential role in erectile dysfunction. ET-1 and NLRP3
activate inflammatory processes by increasing calcium
(Ca) and reactive oxygen species (ROS). In the
present study, we hypothesized that endothelin receptors
(ET and ET) stimulation, through
increased calcium and ROS formation, leads to NLRP3 activation.
Experimental approach: Intracavernosal pressure (ICP/MAP) was
measured in C57BL/6 (WT) mice. Functional and immunoblotting assays were
performed in corpora cavernosa (CC) strips from WT,
NLRP3 and caspase mice after
ET-1 (100 nM) stimulation in the presence of vehicle, MCC950, tiron,
BAPTA AM, BQ123, or BQ788. Key Results: ET-1 gradually reduced
the ICP/MAP in WT mice, and MCC950 administration prevented the effect
of ET-1. ET-1 decreased CC relaxation to ACh and sodium nitroprusside
(SNP) and increased caspase-1 protein expression, effects reversed by
the ET receptor antagonist BQ123. The
ET receptor antagonist BQ788 also reversed the effect
of ET-1 on ACh and SNP relaxation. Additionally, tiron, BAPTA AM, and
NLRP3 genetic deletion prevented the ET-1-induced loss of ACh and SNP
relaxation. Moreover, BQ123 diminished CC caspase-1 expression, while
BQ788 increased caspase-1 and IL-1β levels in a concentration-dependent
manner (100 nM to 10 µM). Furthermore, tiron and BAPTA AM prevented
ET-1-induced increase in caspase-1. In addition, BAPTA AM blocked
ET-1-induced ROS generation. Conclusion and Implications: NLRP3
activation contributes to acute ET-1-induced erectile dysfunction by
mechanisms that depend on ET- and
ET-induced Ca influx and ROS
generation.
Efecto del Lactobacilius acidophilus y Lactobacilius bifidus como probiótico comercial en la dieta del hámster dorado (Mesocricetus auratus)
Authors: Arias Andrade Andrés , Hernández Martínez María Cristina , Corredor Matus José Ricardo
Published: July 2021

Los probióticos han sido considerados por muchos autores como microorganismos y/o sustancias que afectan la flora intestinal por distintos mecanismos de tal manera que sus efectos benéficos no solo se han reportado en tracto gastrointestinal, también en el respiratorio y urogenital. El objetivo del presente trabajo es evaluar, crecimiento y ganancia de peso con el suministro de un coctel probiótico que contenía (Lactobacilius acidophilus y Lactobacilius bifidus), de uso comercial en el hámster dorado para el cual se obtuvieron 20 animales experimentales con una vida en promedio de 8 a 15 días, los cuales se dividieron en dos grupos experimentales, grupo control (GC) y experimental (GM) en cual tuvo una duración de 3 semanas. Los resultados obtenidos muestran que el suministro de probiótico afecto el peso y el crecimiento de los hámsteres durante su desarrollo a la adultez.
Los sistemas integrados de producción agropecuaria como alternativa agroecológica (experiencia Cubana)
Authors: Iglesias J.M. , Funes F. , Machado H. , Soca M.
Published: July 2021

Los sistemas especializados de producción requieren generalmente de un flujo exógeno de recursos y su mantenimiento y estabilidad no dependen de su capacidad propia de sustento. En cambio, los sistemas productivos agroecológicos, que miran hacia los procesos, muestran mayor capacidad de sostenimiento, generando sinergias que permiten potenciar las capacidades naturales de producir alimentos de origen vegetal y animal y de restaurar el equilibrio productivo, ecológico y económico, ante la influencia negativa de cualquier factor interno o externo. Un sistema no es considerado la suma de sus partes, sino el resultado del todo, formado por las partes. En los sistemas agroecológicos se implanta no solo la racionalidad biológica del funcionamiento del suelo, las plantas y los animales, sino que se relaciona con el hombre y su entorno social, económico y político. Aquí se desecha la visión antropocéntrica del mundo y toma lugar la visión biocéntrica, que explica el funcionamiento y evolución de cualquier cambio. Otro aspecto a tener en cuenta son las técnicas tradicionales y los conocimientos locales. Las experiencias acumuladas, los conocimientos tradicionales y locales, incluso los empíricos, en la actividad agropecuaria se trasmiten de generación en generación y son de mucha importancia para lograr resultados productivos y eficientes.
Enfoque social de la inclusión de arreglos silvopastoriles dentro de comunidades penitenciarias en Colombia
Authors: Martínez Javier
Published: July 2021

La Colonia Agrícola como establecimiento carcelario en el país, es quizás la referencia histórica de los procesos de encarcelamiento organizado, en la cual ha existido la intensión siempre de ser pionera en procesos productivos y de intervención terapéutica, desde su creación ha realizado esfuerzo por presentar propuestas de producción ganadera, tanto que este sistema ha surgido después de la tala y quema de los bosques, resultando en agroecosistemas con una escasa cobertura arbórea, con suelos desprotegidos y a menudo carentes de diversidad, al privilegiarse únicamente las pasturas. Esto ha permitido; que las áreas de pastoreo se vuelvan especialmente susceptibles a procesos erosivos, más aún cuando se encuentran en zonas de ladera. Al mismo tiempo; la producción ganadera en forma tradicional, implica generalmente una alta dependencia de insumos externos para rendir, incrementando los costos de producción y ocasionando ambientales. En este sentido, la búsqueda de sistemas de producción ganaderos más sustentables tanto ecológica como económicamente; además de ser socialmente aceptables y fácilmente adoptables, se hace una prioridad. Dentro de este contexto; los sistemas agroecológicos parecen ser una alternativa a corto, mediano y/o largo plazo capaz de cumplir con las demandas actuales de producción. En la actualidad se ha evaluado la inclusión social de arreglos silvopastoriles en la Colonia, como alternativa de tratamiento penitenciario, donde el interno realiza su plan de cambio, mediante la capacitación y la practica en ganadería agroecológica, experiencia recogida en el periodo de 2005 al 2010.
Sales minerales en la ganadería de leche bovina
Authors: Pérez M.A. , Peña F.A. , Benítez M.J.
Published: July 2021

Los bovinos obtienen los minerales necesarios para su metabolismo del medio ambiente en el que se desarrollan. Las deficiencias y desbalances de minerales en la dieta son reconocidas como una de las limitantes en la producción animal. Los minerales cumplen un importante papel en la nutrición, teniendo en cuenta que aunque no proporcionan energía son esenciales para la utilización y síntesis biológica de nutrientes esenciales. En los sistemas intensivos que utilizan vacas de alta producción, la administración de sales minerales permite incrementar el consumo y por ende la productividad de los animales. Los minerales son diariamente utilizados por los animales en el desarrollo de sus funciones fisiológicas normales, y en determinadas ocasiones la falta de estos en la dieta normal del animal es la causa primaria de problemas reproductivos. La implementación de las dietas minerales depende de las deficiencias que presente el suelo y los pastos en los que se alimentan los animales. Sin embargo, la administración de sales mineralizadas de tipo comercial tiene que ser realizada bajo análisis técnicos los cuales arrojen como resultado la fórmula ideal para cada terreno. El presente artículo muestra algunas de las características a tener en cuenta en la alimentación de ganado de lechería en Colombia, partiendo de variables como el desarrollo fisiológico del animal, los requerimientos minerales de acuerdo a su estado de producción y las condiciones de los suelos en los que el animal pastorea.
Implementación del sistema de pastoreo racional Voisin en la finca La Gloria del municipio de Puerto López (Meta)
Authors: Reina D. Carlos , Sánchez Vladimir
Published: July 2021

Este trabajo se realizó en la finca la Gloria de la vereda Melúa del municipio de Puerto López, en el departamento del Meta, la cual está situada a 300 msnm, con una temperatura de 30°C, una humedad relativa de 82%, los suelos que predominan en la región son francoarenosos y ácidos, y con una topografía de 60% plana, 30% ondulada y un 10% quebrada. Los índices de producción de la finca la Gloria en especial el de las ganancias de peso se mantuvieron bajos en un sistema de pastoreo tradicional, por lo tanto, este proyecto consistió en implementar un sistema de pastoreo racional en la finca el cual permitió optimizar el consumo del forraje sin pérdidas significativas, de igual manera, contribuyó en el mejoramiento de los índices de producción de la finca, entre otros beneficios. Se realizó un diagnóstico inicial para conocer el estado de la finca y como se encontraba en términos de suelo, forraje que se ofrecía al ganado, fuentes de agua y demás recursos que permitan determinar en qué condiciones se iba de ejecutar el proyecto. Se planificó con base en el diagnóstico inicial cuales eran las mejores condiciones para la realización del proyecto, al igual, que un presupuesto de acuerdo a lo aprobado entre las partes interesadas en la ejecución. Se ejecutó el proyecto de implementación del sistema de pastoreo racional Voisin de acuerdo a lo establecido y aprobado por parte del productor y se organizó el sistema de pastoreo actual para ayudar en el mejoramiento de los índices de producción (ganancia de peso) en el ganado bovino de la finca. Se logro pasar de producir en 64 hectáreas 21 toneladas de carne a 52 toneladas en la misma área, es decir, 0.3 toneladas de carne por hectárea a 0.8 toneladas de carne por hectárea, además se concientizó a los empleados de la finca la Gloria en buenas prácticas ganaderas y biosanitarias y lo relacionado con el correcto manejo de las praderas.
Comportamiento de la proteína de forraje verde hidropónico en función del tiempo de cosecha
Authors: Moyano Hernández Luis Francisco , Sánchez Moreno Hugo Vladimir
Published: July 2021

El forraje verde hidropónico (FVH) es una de las variantes de la hidroponía;  proceso que consiste en la germinación rápida de semillas viables de algunos cereales realizada en instalaciones adecuadas para tal fin y bajo procesos controlados, por un lapso de tiempo no mayor a los 12 días; 9 de los cuales se suministra a las plántulas soluciones nutritivas, lo que produce al final del ciclo un tapete compuesto por granos germinados, con sus raíces, tallos y hojas verdes; la biomasa vegetal así obtenida es de alta sanidad y calidad nutricional. Constituye pues una muy interesante posibilidad para suplir eficientemente las dietas de animales rumiantes y no rumiantes. Se pretende socializar, los datos, experiencias y resultados obtenidos sobre FVH producido en Colombia, con el ánimo de que este se constituya en una herramienta útil a los interesados en la implementación de esta tecnología. Para desarrollar los objetivos del proyecto, se obtuvo material vegetativo a los 4, 6, 8, 10, 12 y 14 días de cosecha, del cual se tomó una muestra al azar y se realizó análisis bromatológico en el laboratorio de nutrición animal de la Universidad de los Llanos, el cual pretendió establecer el comportamiento de la proteína de FVH en función del tiempo de cosecha. El FVH de Zea maíz presenta su pico máximo de contenido proteico en el día decimo a partir del cual empieza a descender levemente hasta el día doce y de allí en adelante presenta un descenso vertiginoso. El tiempo máximo de germinación de las plántulas no debe exceder el día doce.
Agroforestería para la conservación del suelo y otros recursos naturales
Authors: Ruiz Velez Jessica Fernanda
Published: July 2021

Una definición de agroforestería que abarca varios aspectos es: ciencia interdisciplinaria, con tradición, innovación productiva y conservación de la naturaleza donde existen formas de manejo y aprovechamiento de sistemas y desarrollo de saberes tradicionales y novedosos, fortalecimiento de la identidad cultural, interacciones ecológicas totales de complementariedad del sistema, diversificación del paisaje, uso adecuado de recursos naturales, privilegio del trabajo humano, utilizando tecnologías de bajo impacto ecológico y en la que se presentan relaciones sociales, ambientales y económicas de bienestar, equidad y justicia. El hecho de disminuir las hectáreas de bosque en Suramérica, ha generado perdida de la biodiversidad, degradación de los recursos naturales (agua, aire y suelo), y desplazamiento de algunas tribus indígenas, lo que ha ocasionado una baja en la productividad agrícola y animal, y como si fuera poco, un alto índice de pobreza, de las poblaciones de campesinos que están dedicados a estas actividades. Lo anterior se debe, a la costumbre que poseen los países suramericanos, de poner en práctica modelos con una alta dependencia de agroquímicos, donde los sistemas de producción se basaron en monocultivos, con la importación de paquetes tecnológicos, implementación de maquinaria agrícola no apta para el trópico; que contribuyeron a empeorar la crisis ambiental por la que hoy estamos pasando. Se han planteado una serie de argumentos, orientados hacia la sostenibilidad considerando estrategias para la conservación de recursos naturales, y energía en su ciclicidad; en lo cual la “Agroforestería”, desempeñaría un papel importante debido a la gran variedad de especies arbóreas que existen en el trópico de Suramérica, buscando con ello sistemas amigables con el medio ambiente y así brindar una calidad de vida óptima para los campesinos y su entorno, ya que aumenta la productividad animal y vegetal, así como el mejoramiento de los paisajes.
Importancia de los disruptores endocrinos en la alimentación bovina
Authors: Jaramillo Hernández Dumar Alexander
Published: July 2021

En este artículo de revisión se describen las características químicas de los disruptores endocrinos que pueden contaminar los productos utilizados en la alimentación bovina, así mismo su disponibilidad ambiental y los efectos que generan en la homeostasis de esta especie de interés zootécnico, con especial énfasis en las alteraciones que comprometen el sistema reproductor de machos y hembras de la especie bovina; además de las consecuencias en salud pública generadas por la oferta de productos y subproductos de origen bovino con residuos o trazas de disruptores endocrinos. La ecotoxicología juega un papel importante en la explicación de los efectos postinteracción entre los compuestos xenobióticos y los organismos de un determinado ecosistema; las fuentes de disruptores endocrinos se pueden encontrar en los contaminantes orgánicos persistentes como en los fitoestrógenos y éstos pueden estar presentes en los insumos utilizados para balancear las dietas de los animales en producción generando así las alteraciones neuroendocrinas con consecuencias económicas al reducir los parámetros de reproducción del hato.
Aplicación de buenas prácticas ganaderas en una finca especializada en producción de leche, Usme, Cundinamarca, Colombia
Authors: Romero Hortúa Amalia Johanna , Roa Vega María Ligia , López Martínez Miguel Alberto
Published: July 2021

El objetivo de este trabajo fue aplicar las buenas prácticas ganaderas en la Hacienda “Palo Negro” con el propósito de mejorar la calidad de la leche, enfatizando en la rutina de ordeño y las técnicas de bienestar animal. La finca está ubicada en la vereda “El Destino” en Usme, Cundinamarca, a 3.200 m.s.n.m., con una temperatura promedio de 12°C; tiene un hato de 160 vacas lecheras Holstein puro, cuyo alimento básico son las gramíneas: raigrass (Lolium sp), falsa poa (Holcus lanatus), azul orchoro (Dactylis glomerata) y leguminosas: trébol rojo (Trifolium pratense) y blanco (Trifolium repens). La producción promedio diaria del hato es 16 litros de leche/vaca, se suministra un kg de suplemento concentrado por cinco litros de leche producida. Para iniciar el proceso de certificación de predio libre de brucelosis y tuberculosis, se tomaron muestras de sangre en la totalidad de los animales del hato, las cuales fueron enviadas al laboratorio, los resultados en estas dos pruebas fueron negativos. Con el fin de determinar la presencia de mastitis, se realizó la prueba de CMT (Test de Mastitis California) en la ubre de una muestra de 40 vacas antes de iniciar las buenas prácticas ganaderas y después de aplicarlas, haciendo evaluaciones cada mes. Con la aplicación de buenas prácticas ganaderas disminuyó de manera gradual en seis meses la incidencia de mastitis en las vacas de la finca “Palo Negra” de 78.8 a 58.5%, lo cual indica que 34 vacas de las 160 respondieron a los tratamientos veterinarios, los cuales fueron aplicados rigurosamente. Igual situación se presentó en las unidades formadoras de colonias y recuento de células somáticas las cuales disminuyeron en seis meses de 625.000 Vs 11.680 (leche recién ordeñada) a 2´371.000 Vs 2´019.000 (leche almacenada en cantina).