bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Facile Synthesis of Bis(indolyl)methanes Catalyzed by Ferric Dodecyl Sulfonate [Fe(DS)3] in Water at Room Temperature.
Authors: Wang Shun‐Yi , Ji Shun‐Jun
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Trifluoromethylated 2‐Benzoyl‐ and 2‐Aminoimidazoles from Ring Rearrangement of 1,2,4‐Oxadiazole Derivatives.
Authors: Piccionello Antonio Palumbo , Pace Andrea , Buscemi Silvestre , Vivona Nicolo , Pani Marcella
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Generation of Enantiomerically Pure N‐α‐Carboxyalkylglycolurils.
Authors: Baranov Vladimir V. , Kravchenko Angelina N. , Belyakov Pavel A. , Makhova Nina N.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N‐Methylimidazole‐Promoted Efficient Synthesis of Functionalized 1,3‐Oxazoline‐2‐thiones under Solvent‐Free Conditions.
Authors: Yavari Issa , Hossaini Zinatossadat , Souri Sanaz , Sabbaghan Maryam
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Stable Isoxazolines by [3 + 2] Cycloaddition of Oxaziridines with Alkynes.
Authors: Fabio Marilena , Ronzini Ludovico , Troisi Luigino
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Recyclable Copper(II) Catalyst for the Annulation of Phenols with 1,3‐Dienes.
Authors: Adrio Luis A. , Hii King Kuok
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Improved Syntheses of 5‐Hydroxy‐2‐pyridones (2,5‐Dihydroxypyridines).
Authors: Behrman E. J.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Isocoumarin and Isoquinoline Derivatives
Authors: Mahmoud Mahmoud R. , El‐Shahawi Manal M. , Farahat Samira E.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Strategic Studies in the Syntheses of Novel 6,7‐Substituted Quinolones and 7‐ or 6‐Substituted 1,6‐ and 1,7‐Naphthyridones.
Authors: Morgentin Remy , Pasquet Georges , Boutron Pascal , Jung Frederic , Lamorlette Maryannick , Maudet Mickael , Ple Patrick
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pd—Cu Catalyzed Heterocyclization During Sonogashira Coupling: Synthesis of 2‐Benzylimidazo[1,2‐a]pyridine.
Authors: Bakherad Mohammad , Nasr‐Isfahani Hossein , Keivanloo Ali , Doostmohammadi Nesa
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Thieno[2,3‐b][1,6]naphthyridines and Pyrimido[4′,5′:4,5]thieno[2,3‐b][1,6]naphthyridines.
Authors: Abdel‐Wadood Fatma K. , Abdel‐Monem Maisa I. , Fahmy Atiat M. , Geies Ahmed A.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Microwave‐Assisted Desulfitative Dimethylamination of the 2(1H)‐Pyrazinone Scaffold Using N,N‐Dimethylformamide.
Authors: Sharma Anuj , Mehta Vaibhav Pravinchandra , Van der Eycken Erik
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Atom‐Efficient Synthesis of 2,6‐Diazacyclophane Compounds Through Alcoholysis/Reduction of 3‐Nitroarylmethylene‐2,5‐piperazinediones.
Authors: Gonzalez Juan Francisco , de la Cuesta Elena , Avendano Carmen
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Benzimidazo[1,2‐a]pyrido[2,1‐c]pyrazinium Systems.
Authors: Kim D. G.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Antiarrhythmic Properties of Some Aroxyethylamine Derivatives with Adrenolytic Activity.
Authors: Maciag D. , Bednarski M. , Filipek B. , Pociecha T. , Szkaradek N. , Marona H.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted One‐Pot Synthesis of Benzo[b][1,4]oxazin‐3(4H)‐ones via Smiles Rearrangement.
Authors: Zuo Hua , Meng Lijuan , Ghate Manjunath , Hwang Kyu‐Hyeon , Cho Yong Kweon , Chandrasekhar S. , Reddy Ch. Raji , Shin Dong‐Soo
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sulfamic Acid as an Effective Catalyst in Solvent‐Free Synthesis of β‐Enaminoketone Derivatives and X‐Ray Crystallography of Their Representatives.
Authors: Xia Min , Wu Bin , Xiang Guo‐Feng
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Montmorillonite K10: An Efficient Catalyst for Solvent‐Free Synthesis of 1,5‐Benzodiazepine Derivatives
Authors: An Li‐Tao , Ding Fei‐Qing , Zou Jian‐Ping , Lu Xiao‐Hua
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Synthesis of Dialkyl 1‐Azidoalkylphosphonates Using Tetramethylguanidinium Azide as Azidation Agent.
Authors: Blaszczyk Roman , Gajda Tadeusz
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Six New Cembranolides from the Hainan Soft Coral Lobophytum sp.
Authors: Chen Si‐Han , Guo Yue‐Wei , Huang Hui , Cimino Guido
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cassane‐Type Diterpenoids from the Seeds of Caesalpinia magnifoliolata
Authors: Yin Yinhua , Ma Lei , Hu Li‐Hong
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Stereoselective Total Synthesis of (‐)‐Seychellene.
Authors: Srikrishna A. , Ravi G.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Xenimanadins A—D, a Family of Xenicane Diterpenoids from the Indonesian Soft Coral Xenia sp.
Authors: Fattorusso Ernesto , Romano Adriana , Taglialatela‐Scafati Orazio , Achmad M. Janib , Bavestrello Giorgio , Cerrano Carlo
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Free Aerobic Chemoselective Oxidation of β‐Ionone Catalyzed by N‐Hydroxyphthalimide/Co(acac)2.
Authors: Gong Nian‐hua , Tang Rui‐Ren , Zhou Ya‐ping , Xu Hai‐feng
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Colletoic Acid (I), a Novel 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor from Colletotrichum gloeosporioides SANK 21404.
Authors: Aoyagi Azusa , Ito‐Kobayashi Mariko , Ono Yasunori , Furukawa Yoji , Takahashi Mizuki , Muramatsu Yasunori , Umetani Megumi , Takatsu Toshio
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solution‐Phase Synthesis of 2‐Cyano and 2‐Amido Aziridinyl Peptides.
Authors: Fioravanti Stefania , Massari Davide , Morreale Alberto , Pellacani Lucio , Tardella Paolo A.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of β2‐Homophenylalanine Derivatives by Negishi Cross‐Coupling Reactions.
Authors: Bartrum Hannah E. , Adams Harry , Caggiano Lorenzo , Jackson Richard F. W.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fe2(SO4)3×xH2O‐Catalyzed per‐O‐Acetylation of Sugars Compatible with Acid‐Labile Protecting Groups Adopted in Carbohydrate Chemistry.
Authors: Shi Lei , Zhang Guisheng , Pan Feng
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of Benzyl‐Protected β‐Galactosides by Propionitrile‐Mediated Glycosylation.
Authors: Ueki Akiharu , Hirota Masafumi , Kobayashi Yuta , Komatsu Keiko , Takano Yutaka , Iwaoka Michio , Nakahara Yuko , Hojo Hironobu , Nakahara Yoshiaki
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phenolic Glycosides from Viburnum fordiae Hance and Their Antioxidant Activities
Authors: Wu Bin , Zheng Xintian , Qu Haibin , Cheng Yiyu
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Total Synthesis of Roquefortine C and a Rationale for the Thermodynamic Stability of Isoroquefortine C over Roquefortine C.
Authors: Shangguan Ning , Hehre Warren J. , Ohlinger William S. , Beavers Mary Pat , Joullie Madeleine M.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Studies Towards Complex Bridged Alkaloids: Regio‐ and Stereocontrolled Enolate Chemistry of 2,5‐Diketopiperazines.
Authors: Pichowicz Mark , Simpkins Nigel S. , Blake Alexander J. , Wilson Claire
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sterenin A, B, C and D, Novel 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitors from Stereum sp. SANK 21205.
Authors: Ito‐Kobayashi Mariko , Aoyagi Azusa , Tanaka Isshin , Muramatsu Yasunori , Umetani Megumi , Takatsu Toshio
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Synthesis of the 2‐Azaanthraquinone Alkaloid, Scorpinone, Based on Two Microwave‐Assisted Pericyclic Reactions.
Authors: Choshi Tominari , Kumemura Teppei , Nobuhiro Junko , Hibino Satoshi
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Borononucleotides: Synthesis, and Formation of a New Reversible Boronate Internucleosidic Linkage.
Authors: Luvino Delphine , Baraguey Carine , Smietana Michael , Vasseur Jean‐Jacques
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Constituents from Leaves of Scolopia chinensis.
Authors: Lu Ya‐Nan , Xie Guang‐Bo , Bi Dan , Shi Hai‐Ming , Tu Peng‐Fei
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Total Synthesis of (+)‐Negamycin, a Potential Chemotherapeutic Agent for Genetic Diseases.
Authors: Hayashi Yoshio , et al. et al.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lysianadioic Acid (I), a Carboxypeptidase B Inhibitor from Lysiana subfalcata.
Authors: Buchanan Malcolm S. , Carroll Anthony R. , Edser Annette , Sykes Melissa , Fechner Gregory A. , Forster Paul I. , Guymer Gordon P. , Quinn Ronald J.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ascochytatin, (I) a Novel Bioactive Spirodioxynaphthalene Metabolite Produced by the Marine‐Derived Fungus, Ascochyta sp. NGB4
Authors: Kanoh Kaneo , Okada Ario , Adachi Kyoko , Imagawa Hiroshi , Nishizawa Mugio , Matsuda Satoru , Shizuri Yoshikazu , Utsumi Ryutaro
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Self‐Catalyst Growth of Single‐Crystalline CaB6 Nanostructures.
Authors: Xu Junqi , Zhao Yanming , Zou Chunyun , Ding Qiwei
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Manganese, Technetium and Rhenium
Authors: West Andrew J.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Macrocycles in Supramolecular Chemistry: From Dynamic Combinatorial Chemistry to Catalysis
Authors: Luening U.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Wallach Rearrangement as a Method for the Synthesis of Functionalized Azobenzocrown Ethers
Authors: Luboch E.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Application of Combinatorial Chemistry Science on Modern Drug Discovery
Authors: Kennedy J. Phillip , Williams Lyndsey , Bridges Thomas M. , Daniels R. Nathan , Weaver David , Lindsley Craig W.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Monosaccharides and Analogues. Part 1. Applications of Chemoenzymatic Methods and Organocatalysis
Authors: Robina Inmaculada , Vogel Pierre
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heterocycle Synthesis via Radical Reactions
Authors: Naito Takeaki
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Processes for the Synthesis of Biologically Relevant Heterocycles
Authors: Banwell Martin G.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Use of Sultines in the Asymmetric Synthesis of Polypropionate Antibiotics
Authors: Vogel Pierre , Turks Maris , Bouchez Laure , Craita Cotinica , Huang Xiaogen , Murcia M. Carmen , Fonquerne Freddy , Didier Charles , Flowers Christopher
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthetic—Technical Development of Oseltamivir Phosphate (Tamiflu) — A Race Against Time
Authors: Abrecht Stefan , Federspiel Muriel Cordon , Estermann Heinrich , Fischer Rolf , Karpf Martin , Mair Hans‐Jurgen , Oberhauser Thomas , Rimmler Gosta , Trussardi Rene , Zutter Ulrich
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Determination of Absolute Configuration — An Overview Related to This Special Issue
Authors: Allenmark Stig , Gawronski Jacek
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Synthesis of Peptidoglycan Fragments for Elucidation of the Immunostimulating Mechanism
Authors: Fujimoto Yukari , Inamura Seiichi , Kawasaki Akiko , Shiokawa Zenyu , Shimoyama Atsushi , Hashimoto Takashi , Kusumoto Shoichi , Fukase Koichi
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Free‐Radical Mechanisms of Formation of Polysaccharides Radiation Destruction Products
Authors: Sharpatyi V. A.
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: General and Practical Synthesis of Benzothiazoles
Authors: Mase Toshiaki , Itoh Takahiro
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Synthesis of Bioactive Quinazolines and Quinazolinones
Authors: Besson Thierry , Chosson Elizabeth
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Adsorptive Stripping Voltammetry of Environmental Carcinogens
Authors: Barek Jiri , Peckova Karolina , Vyskocil Vlastimil
Published: August 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Theoretical Study on Proton‐Transfer Reaction of Intracellular Second‐messenger 3′,5′‐Cyclic Nucleotide
Authors: ZHANG Ai‐Hua , YANG Bao‐Hua , LI Zong‐He
Published: August 2008

The gas‐phase proton‐transfer reaction mechanism of intracellular second‐messenger 3′,5′‐cyclic nucleotide (cAMPm) has been theoretically investigated at the B3LYP/6‐31G∗︁ ∗︁ level. One or two H2O molecules have been used to simulate the catalyst. It is found that H shift reaction between conformation Bm and conformation Dm of cAMPm involves a cyclic transition state with one or two water molecules as a shuttle. Furthermore, H shift reaction proceeds easily with the participation of two water molecules. The results provide evidence in theory to study proton‐transfer reaction mechanism of related phosphodiesters. Our present calculations have rationalized all the possible reaction channels.
Interaction Mechanism of Anthracene with Benzoic Acid and Its Derivatives
Authors: HE Ying‐Ying , WANG Xiao‐Chang , FAN Xiao‐Yuan , ZHAO Bo , JIN Peng‐Kang
Published: August 2008

Interaction mechanism of anthracene, one of the typical polycyclic aromatic hydrocarbons, with benzoic acid and its hydroxyl‐substituted derivatives, o‐hydroxylbenzoic acid and p‐hydroxylbenzoic acid, were studied using FTIR, UV and fluorescence spectra. The experiments confirmed that there was a specific and oriented interaction between anthracene and the aromatic carboxylic acids, and the bonding mode depended on both the chemical structure of reactants and acidity of solution. The π‐H hydrogen bond played a main role in the interaction between anthracene and the aromatic carboxylic proton of benzoic acid or o‐hydroxylbenzoic acid when pH≤ pKa, and the π‐π electron donor‐acceptor (EDA) interaction increasingly became the main binding mode when pH>pKa. The decrease of interaction intensity of benzoic acid was observed by introducing hydroxyl at its ortho position. The special D‐π‐A structure of p‐hydroxylbenzoic acid made it easy to form the planar multi‐molecule congeries that could interact with anthracene, so the interaction between anthracene and p‐hydroxylbenzoic acid always followed the π‐π EDA model no matter the solution acidity. For p‐hydroxylbenzoic acid, the π‐π interaction mode remained unchanged when pH increased from 2.0 to 10.0, and the binding intensity was higher than that between benzoic acid and anthracene because of the formation of the multi‐molecule congeries.
Self‐assembly of Copper Sulfide Nanoparticles to Solid, Hollow Spherical and Wire‐Shaped Structures
Authors: NAN Zhao‐Dong , WEI Cheng‐Zhen , WANG Xue‐Ying , HAO Hai‐Yan
Published: August 2008

Copper sulfides, such as Cu7S4, Cu1.8S, Cu1.81S and Cu2S, in the wire‐like, and solid and hollow ball‐like shapes congregated from nano‐spherical particles and nanoslices, have been prepared by a solvothermal method using a mixture of water and ethylene glycol as solvent. CuSO4 and thiourea were used as the starting materials without assistance of any surfactant or template. The results show that the water content in the solvent affects the morphology of the samples, and the reaction time and temperature affect the crystal structure and morphology. On the basis of the obtained results, the formation processes of different morphologies of copper sulfides can be interpreted by the following mechanism: nanoparticles of copper sulfides initially formed, then the wire‐like structures were gradually created, and finally translated to solid and hollow spherical structures under the different experimental conditions.
Water as a Direct Hydrogen Donor in Supercritical Carbon Dioxide: A Novel and Efficient Zn‐H2O‐CO2 System for Chemo‐selective Reduction of Nitrobenzenes to Anilines
Authors: JIANG Huan‐Feng , DONG Yao‐Sen
Published: August 2008

An eco‐friendly and cheap Zn‐H2O‐CO2 system was presented for chemoselective reduction of nitrobenzenes to anilines with high yields (80% –97% isolated yields) in supercritical carbon dioxide. This process brings together the very important green chemistry technologies–the use of carbon dioxide as a solvent and the use of water as a hydrogen donor.
Solvent‐free Thia‐Michael Addition Reactions Using 3‐[Bis(alkylthio)methylene]pentane‐2,4‐diones as Efficient and Odorless Thiol Equivalents
Authors: LIN Chun , ZHAO Xiao‐Liang , OUYANG Yan , YU Hai‐Feng , DONG De‐Wen
Published: August 2008

3‐[Bis(alkylthio)methylene]pentane‐2,4‐diones (1a and 1b) have been investigated as nonthiolic and odorless thiol equivalents for thia‐Michael addition reactions under solvent‐free conditions. Promoted by HCl (aq.), the cleavage of compounds 1 took place, and the in‐situ generated thiols underwent facile conjugate addition to α?β‐unsaturated carbonyl compounds 2 affording the corresponding ????????‐keto sulfides 3 in high yields.
Enantioselective Sulfide Oxidation Catalyzed by 2,10‐Camphanediol Derived Titanium Complex and Its Mechanism
Authors: ZENG Qing‐Le , TANG Hong‐Yan , ZHANG Song , LIU Jian‐Chuan
Published: August 2008

Cumyl hydroperoxide (CHP) and tert‐butyl hydroperoxide (TBHP) produced (R)‐ and (S)‐sulfoxide in 2,10‐camphanediol‐titanium catalyzed sulfoxidation, respectively. During kinetic resolution, the sulfoxide configuration was reversed with CHP, but kept with TBHP. Based on these results and the ESI‐MS data, the mechanism of sulfoxidation was proposed to be intramolecular nucleophilic oxygen transfer to a coordinated sulfide.
An Effective Hg2+‐Selective Fluorescent Chemosensor Based on a Calix[4]arene Bearing Four Dansyl Amides
Authors: LI Guang‐Ke , LIU Min , YANG Guo‐Qiang , CHEN Chuan‐Feng , HUANG Zhi‐Tang
Published: August 2008

A new calix[4]arene‐based fluorescent chemosensor bearing four dansyl amides on the upper rim (1) was conveniently synthesized, which showed high sensitivity and selectivity toward Hg2+ over a wide range of metal ions in 50% aqueous acetonitrile. The complexation of Hg2+ ion induced a strong fluorescence quenching of 1 due to a well‐defined electron transfer process from the dansyl group(s) to the metal center. Compared with compounds 2 and 3, tetradansyl amide substituted calix[4]arene 1 showed a preorganized and coordinated complexing site for metal ions. Moreover, the detection limit for Hg2+ was found to be 3.41×10−6 mol·L−1, which might make 1 a potentially practical Hg2+‐selective fluorescent sensor in aqueous system.
Gold‐catalyzed Alkyne Hydroxylation: Synthesis of 2‐Substituted Benzo[b]furan Compounds
Authors: ZHANG Yuan , XIN Zhi‐Jun , XUE Ji‐Jun , LI Ying
Published: August 2008

A strategy concerning the synthesis of 2‐substituted benzo[b]furan compounds from o‐alkynyl phenols via a gold‐catalyzed alkyne hydroxylation is described, which allows the rapid synthesis of various 2‐substituted benzo[b]furan derivatives in excellent yields under mild conditions. The o‐alkynyl phenol precursors were readily prepared with a Sonogashira coupling reaction.
Anhydrous K2CO3‐mediated Tandem Deprotection of (Un)substituted Phenyl Methanesulfonate/SNAr Reactions to Construct Unsymmetrical Diphenyl Ethers in an Ionic Liquid
Authors: XU Hui , YE Fei , DAI Hui‐Ling
Published: August 2008

In an ionic liquid [Bmim]BF4 (1‐butyl‐3‐methylimidazolium tetrafluoroborate), an efficient anhydrous K2CO3‐mediated tandem deprotection of (un)substituted phenyl methanesulfonates and nucleophilic aromatic substitution reactions (SNAr) with activated (un)substituted phenyl halides to synthesize unsymmetrical diphenyl ethers has been described. The solvent could be recycled without loss of any efficiency, and the procedure was quite convenient, practical and environmentally benign.
Synthesis, Characterization and Properties of Asymmetric Methide Anion Based Ionic Liquids Containing Nitrile Groups
Authors: ZOU Ting , LU Liang , LIU Xiu‐Li , ZHANG Zhan , WANG Li‐Bing , FU Xian‐Lei , GAO Guo‐Hua , KOU Yuan , HE Ming‐Yuan
Published: August 2008

A series of asymmetric methide anion based ionic liquids containing nitrile groups have been synthesized for the first time using the method of ion‐exchange between sodium/potassium methide and various quaternary bromide/chloride salts of trimethylamine, triethylamine, tributylamine,N‐methylpyrrolidine, andN‐methylimidazole. All of the functionalised ionic liquids were characterized by IR,1H,13C NMR, MS and elemental analysis. The decomposition temperature of the ionic liquids measured via TGA ranged from 219 to 339 °C. The functionalised ionic liquid, [Bmim][C(CN)2COCH3], was used as a ligand for Suzuki coupling reaction. The yields of the coupling reaction increased 10% –15% by the addition of the functionalised ionic liquid, [Bmim][C(CN)2COCH3].
Flavin‐dependent Tryptophan Halogenases and Their Use in Formation of Novel Tryptophan Derived Compounds
Authors: CHEN Xian‐Ping , HUANG Mei‐Fa , WANG Bin
Published: August 2008

Flavin‐dependent halogenases are now known to play a significant role in the introduction of chloride and bromide into activated organic molecules. Herein a new strategy was reported to formate monodechloroaminopyrrolnitrin derivative 3‐(2‐amino‐4‐chlorophenyl)pyrrole, which is a key intermediate for the analysis and mutagenesis of pyrrolnitrin biosynthesis, by combinatorial biosynthesis using regioselective tryptophan halogenases. The successful production in Pseudomonas, with combinatorial cultivating method, demonstrates the feasibility of the new approach to modify and analyze these important secondary metabolite pathways.
Oxalic Acid Catalyzed Three Component One Pot Synthesis of 3,4‐Dihydroquinazolin‐4‐ones
Authors: SANGSHETTI Jaiprakash‐N. , KOKARE Nagnnath‐D. , SHINDE Devanand‐B.
Published: August 2008

An efficient one‐pot method for synthesis of an array of 3,4‐dihydroquinazolin‐4‐ones from anthranilicacid, triethyl orthoformate, and anilines using oxalic acid as a catalyst was described. The present protocol offers improvements for the synthesis of 3,4‐dihydroquinazolin‐4‐ones with regard to short reaction time, high yields of products, and simplicity in operation.
Synthesis of Polyfunctionally Substituted Fused Pyrimidine Derivatives as Antimicrobial Agents
Authors: EISSA Abd EI‐Monem Mohamed Farag
Published: August 2008

A variety of pyrimidine derivatives 2–4 and annulated pyrimidine derivatives 5–17 have been synthesized via a sequence of heterocyclization reaction of readily available 6‐naphthyl‐4‐oxo‐2‐thioxo‐1,2,3,4‐tetrahydroprimidine‐5‐carbonitrile (1) with different acidic and basic reagents. The new compounds were synthesized with the aim of study of their antimicrobial activity. The structures of all synthesized compounds were elucidated by elemental analysis and spectroscopic studies.
Water Soluble Gold(I)‐diacetyl‐1,3,5‐triaza‐7‐phosphaadamantane‐arylazoimidazole Complexes: Synthesis and Spectroscopic Study
Authors: BYABARTTA Prithwiraj
Published: August 2008

Reaction of [Au(DAPTA)(Cl)] with RaaiR′ in CH2Cl2 medium following ligand addition leads to [Au(DAPTA)(RaaiR′)](Cl) [DAPTA=diacetyl‐1,3,5‐triaza‐7‐phosphaadamantane, RaaiR′ =p‐R‐C6H4‐N=N‐ C3H2‐NN‐1‐R′, (1–3), abbreviated as N,N′‐chelator, where N(imidazole) and N(azo) represent N and N′, respectively; R=H (a), Me (b), Cl (c) and R′ =Me (1), CH2CH3 (2), CH2Ph (3)]. The 1H NMR spectral measurements in D2O suggest methylene, CH2, in RaaiEt gives a complex AB type multiplet while in RaaiCH2Ph it shows AB type quartets. 13C NMR spectrum in D2O suggest the molecular skeleton. The 1H‐1H COSY spectrum in D2O as well as contour peaks in the 1H‐13C HMQC spectrum in D2O assign the solution structure.
Synthesis of Protected N‐Acetylchitooligosaccharide and Its Analogues: A Versatile Approach for the Synthesis of Complex Oligosaccharides of 2‐Amino‐2‐deoxy Sugar
Authors: ZHU Zhen‐Yuan , ZHANG Yong‐Min , SUN Chao , YAO Yan‐Ping
Published: August 2008

A stepwise synthesis of oligosaccharide chains containing 2‐amino‐2‐deoxy‐D‐glucopyranose units was elaborated as a new versatile approach for preparation of biologically important oligosaccharides having 2‐amino‐ 2‐deoxysugars. Utilizing N‐phthalic acyl group as the protective group of amine, and phenylthiolate as the leaving group at the reducing terminal, protected N‐acetylchitooligosaccharide and its analogues, methyl (3‐O‐acetyl‐4,6‐O‐ benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranosyl)‐(1→4)‐3‐O‐acetyl‐6‐O‐benzyl‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranoside 4, methyl (3‐O‐acetyl‐4,6‐O‐benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐gluco‐pyranosyl)‐(1→4)‐ (3‐O‐acetyl‐6‐O‐benzyl‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranosyl)‐(1→4)‐3‐O‐acetyl‐6‐O‐benzyl‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranoside 6, methyl (3‐O‐acetyl‐4,6‐O‐benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranosyl)‐(1→3)‐4,6‐O‐benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranoside 8, and methyl (3‐O‐acetyl‐4,6‐O‐benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranosyl)‐(1→3)‐(4,6‐O‐benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranosyl)‐(1→3)‐4,6‐O‐benzylene‐2‐deoxy‐2‐phthalimido‐β‐D‐glucopyranoside 10, were designed and synthesized by amino glucose as the starting material, which were all characterized by 1H NMR, 13C NMR and HRMS.
Targeting the Open‐Flap Conformation of HIV‐1 Protease with Pyrrolidine‐Based Inhibitors
Authors: Böttcher Jark , Blum Andreas , Dörr Stefanie , Heine Andreas , Diederich Wibke E. , Klebe Gerhard
Published: August 2008

HIV protease is a well‐established drug target in antiviral chemotherapy. Immense research efforts have been made to discover effective inhibitors, thus making the enzyme one of the most studied and best characterized proteins. Although the protease exhibits high flexibility, all approved drugs target virtually the same protein conformation. The development of viral cross‐resistance demands the generation of inhibitors with novel scaffolds and deviating modes of binding. Herein we report the design and the short, high‐yielding stereoselective synthesis of a series of chiral, symmetric pyrrolidine‐based inhibitors targeting the open‐flap conformation of the protease. The obtained co‐crystal structure with one derivative provides a valuable starting point for further inhibitor design.
Anti‐Inflammatory Activity of a New Class of Nitric Oxide Synthase Inhibitors That Release Nitric Oxide
Authors: Botta Maurizio , Distrutti Eleonora , Mencarelli Andrea , Parlato Maria Cristina , Raffi Francesco , Cipriani Sabrina , Fiorucci Stefano
Published: August 2008

Nitric oxide (NO) is a gaseous mediator that exerts key regulatory functions in mammalian cells. Low levels of NO exert homeostatic functions and counteract inflammation, whereas high amounts of NO cause tissue destruction and cellular death. Herein we describe a new class of nitric oxide synthase (NOS) inhibitor NO‐donating drugs (NI‐NODs). Human endothelial cells and human monocyte‐based activity screening showed that NI‐NODs inhibit IL‐1β production, modulate PGE2 production, and protect against apoptosis. In a rodent model of colitis, NI‐NOD1 and NI‐NOD2 potently decreased inflammation. These data show that NI‐NODs are effective in both in vitro and in vivo models of inflammation, mimicking the positive effects of low levels of NO and suppressing NOS‐induced NO production.
Clinical manifestations and beta cell function in Swedish diabetic children have remained unchanged during the last 25 years
Authors: Nordwall Maria , Ludvigsson1 Johnny
Published: August 2008

Background

The incidence of type 1 diabetes in childhood has doubled in Sweden during the last decades. Environmental factors may cause a different disease process, residual beta cell function and clinical manifestation. Insulin therapy has become more intensive. The aim of this study was to examine the clinical characteristics at onset, C‐peptide secretion during the first years after diagnosis and if there was any secular trends during the last 25 years.

Methods

All 316 children diagnosed with type 1 diabetes during 1976–2000 and living in the Linköping area were included. Information about clinical characteristics at diagnosis, duration of partial remission, insulin therapy at diagnosis and during the first years was collected from medical records. C‐peptide secretion (fasting and stimulated) was measured regularly during the first 5 years. For analysis, the population was divided in five cohorts according to the year of diagnosis.

Results

The clinical characteristics at onset were unchanged as well as duration of partial remission. C‐peptide secretion was highest after 3 months and then declined gradually. After 5 years 32.7% of the patients had measurable fasting C‐peptide, but only 6.5% > 0.1 nmol/L. HbA1c and insulin doses were lower in patients with persistent fasting C‐peptide secretion > 0.1 nmol/L. The cohort 1996–2000 had higher stimulated C‐peptide secretion at diagnosis and at 3 months, after longer follow‐up there was no difference.

Conclusion

The clinical characteristics at diagnosis, partial remission and duration of C‐peptide secretion have remained largely unchanged for the last 25 years. Copyright © 2008 John Wiley & Sons, Ltd.
A prospective study of loss of control eating for body weight gain in children at high risk for adult obesity
Authors: Tanofsky‐Kraff Marian , Yanovski Susan Z. , Schvey Natasha A. , Olsen Cara H. , Gustafson Jennifer , Yanovski Jack A.
Published: August 2008

Objective

Limited data suggest that disordered‐eating may predispose children to excessive weight gain. We investigated the relationship between baseline responses to the Eating Disorder Examination adapted for Children (ChEDE) and change in BMI (kg/m2) in children at high risk for adult obesity.

Method

Children (6–12 years) were administered the ChEDE to assess loss of control (LOC) eating, dietary restraint, and eating, shape, and weight concern. Height and weight were measured at baseline and annually.

Results

Between July, 1999, and August, 2007, 772 measurements were obtained from 143 children over 4.5 ± 1.9 years. LOC eating predicted an increased rate of BMI growth over time (p = .02). Compared with children without LOC, those reporting LOC gained an additional mean 2.4 kg of weight per year.

Conclusion

LOC is a salient predictor of weight gain during middle childhood. Interventions that decrease LOC eating should be evaluated for their ability to prevent excessive pediatric weight gain. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2009