bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the Implementation of Minimum Service Standards (SPM) on the Minimum Service Quality of Hospitals: A Case Study at Mentawai Islands Regional Hospital, West Sumatera, Indonesia
Authors: Fadlika Avissa , Rizanda Machmud  , Abdi Setya
Published: June 2024

Minimum service standards (SPM) are an important instrument in ensuring the quality of health services in hospitals. This research aims to analyze the implementation of SPM on minimum service quality at the Mentawai Islands Regional Hospital, West Sumatera, Indonesia. This research uses a mixed-method design with a sequential explanatory approach. The quantitative phase involved collecting secondary data from medical records and patient satisfaction surveys (n=300). Logistic regression analysis is used to identify the relationship between SPM implementation and service quality. The qualitative stage involved in-depth interviews with hospital management (n=5) and health workers (n=10) to explore factors influencing SPM implementation. The results of the quantitative analysis show that the implementation of SPM is significantly associated with an increase in minimum service quality, especially in the aspects of patient safety, clinical effectiveness and patient experience. Qualitative interviews revealed that factors such as resource availability, management commitment, and staff training influence the success of SPM implementation. Effective implementation of SPM contributes to improving the minimum service quality at the Mentawai Islands Regional Hospital. To optimize the implementation of SPM, increasing the availability of resources, strengthening management commitment and ongoing training programs for staff is needed.
Perfect Timing for Canakinumab Use in Gout
Authors: Tanadi Caroline , Oey Cindy
Published: June 2024

Gout is an inflammatory disease caused by the deposition of monosodium urate (MSU) crystals. Recently, the American College of Rheumatology (ACR) has recommended the usage of interleukin (IL)-1 inhibitor in gout patients who are refractory to typical anti-inflammatory drugs. An example of IL-1 inhibitor is canakinumab. Not much is known regarding the usage of canakinumab in gout arthritis. Thus, we decided to conduct a narrative review that summarizes the efficacy and safety of canakinumab in gout patients. In this review, we found that canakinumab is superior to non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids in treating acute gout flares. In addition, canakinumab may also be considered as a preventive therapy for gout flares in patients receiving urate-lowering therapy. Overall, canakinumab has mild side effects but may occasionally cause serious infections. Canakinumab is also generally safe for use during pregnancy. Due to the lack of studies, the safety of canakinumab in lactating women, geriatric patients, and patients with hepatic or renal impairment is still unknown.
Correlation between sCTLA-4 and sCD86 Levels with Disease Activity of Systemic Lupus Erythematosus (SLE) Patients Based on SLEDAI Score
Authors: Eldatarina Helsa , Handono Kalim  , Kusworini Handono  , Mirza Zaka Pratama
Published: June 2024

Background. Systemic Lupus Erythematosus (SLE) is an autoimmune disease with multisystem involvement which arises from multifactorial causes. Continuous exposure to autoantigens and chronic activation of the immune system, especially memory T lymphocytes, contribute to premature immunosenescence. sCTLA-4 and sCD86 are soluble costimulatory molecules of CTLA-4 and CD86, which play a role in the occurrence of immunosenescence in SLE. The presence of immunosenescence will cause higher morbidity and mortality. This research was conducted to establish the correlation between the increased levels of sCTLA-4 and sCD86 and the severity of SLE, as measured by the SLE Disease Activity Index (SLEDAI) score.
Methods. This analytical observational research utilized a cross-sectional approach involving 35 female SLE patients diagnosed according to the SLICC 2012 criteria. SLE disease activity was measured using SLEDAI score. Serum sCTLA-4 and sCD86 levels were measured using the ELISA method. Statistical analysis was conducted using the Mann-Whitney test for comparisons and the Spearman test for correlation analysis, with a significance level of p<0.05.
Results. sCTLA-4 levels were higher and significantly different in patients with moderate SLE (p=<0.001; p<0.05), and there was no significant difference in sCD86 levels (p=0.915; p>0.05). Increased sCTLA-4 levels were positively correlated with the severity of SLE (r =0.361, p=0.033), while no significant correlation was observed in sCD86 levels (r=-0.094, p=0.591).
Conclusion. Elevated sCTLA-4 levels were positively correlated with increased severity of SLE based on the SLEDAI score.
GENDER NORMS AND DEMOGRAPHICS IN ENTREPRENEURSHIP AND DIGITAL FINANCIAL SERVICES UTILIZATION
Authors: Ngware Stephen Githaiga
Published: June 2024

This study sought to estimate gender norms and demographics in entrepreneurship impact in the utilization of digital financial services (DFS) in the context of Kenya using the 2021 FinAccess Survey, which is a joint initiative of the Kenya National   Bureau of Statistics (KNBS), Financial Sector Deeping (FSD) Kenya, and the Central Bank of Kenya (CBK). It also aims to identify the obstacles and difficulties that women encounter when embracing and utilizing digital financial services. The study employed the Probit Model to identify the gender differences in access to DFS in Kenya. Consumer behavior theory was used to determine consumer demand for digital financial services (DFS).  The findings showed that education level, gender, digital credit, mobile ownership, age, and income levels significantly explain the utilization of diverse digital financial services, including digital credit. A significant 78 percent of the population was found to have adopted digital financial services (DFS). The study recommends robust enactment and implementation of policies with a sole focus on the adjustment of income, mobile acquisition, and improvement of education levels amongst individuals, which would enhance the usage and access of digital financial services in Kenya, particularly among women. To overcome mobile ownership barriers, subsidized smartphone initiatives and expansion of network coverage in rural and underserved areas have emerged as pivotal strategies. These actions would effectively improve access to digital financial services by increasing mobile ownership, particularly among women. This study adds to the expanding corpus of research on gender studies and digital financial services. Scholars, researchers, and academics interested in these fields will be invaluable resources.
Prophylactic and therapeutic potential of vitamin D in asthma during the COVID-19 pandemic: the new hope?
Authors: Papamichael Maria Michelle , Katsardis Charis
Published: June 2024

Over the last two decades, the emergence of lethal virulent strains of coronavirus (CoV), including the severe acute respiratory syndrome CoV 2 (SARS-CoV-2), which is responsible for the coronavirus disease 2019 (COVID-19) pandemic, has become a matter of great attention to the scientific community. Despite the implementation of preventive measures throughout the world, the spread of this disease and associated co-morbidities and mortality continue in all countries, continents, and populations of all ages. COVID-19 is highly contagious. Clinical manifestations are diverse and range from asymptomatic, mild to severe, life-threatening complications in the elderly and patients with underlying conditions such as cardiovascular disease, diabetes, obesity, and asthma. In addition, viral infections can trigger asthma attacks. To date, there is no specific treatment schema to combat COVID-19 disease. Current patient care revolves around disease severity and supportive treatment of symptoms from home-rest in mild disease to anti-viral therapy, oxygen support, anti-inflammatories, and anti-coagulants in severe COVID-19. Regarding prevention, the World Health Organization recommends vaccination, social distancing, quarantine, the wearing of surgical masks, and handwashing. In many countries, vaccination is optional, and given that parents are often reluctant to vaccinate themselves and their children for fear of side effects, identifying ways to enhance or support the immune system to prevent infection or improve recovery in vulnerable populations is worth investigating. Furthermore, research has focused on the pharmacological management of COVID-19 symptoms and much less has been published on nutrition therapy. Therefore, the scope of this review is to summarize the latest evidence on the use of vitamin D to support the metabolism and the immune system of asthma patients during the COVID-19 pandemic. A brief overview of asthma and COVID-19 pathophysiology, COVID-19 treatment guidelines for asthma patients, and the role of vitamin D in lung health, including the optimal blood level required to enhance immunity, will be suggested.
Mechanism of the blood-brain barrier modulation by cadherin peptides
Authors: Farokhi Elinaz , Alaofi Ahmed L. , Prasasty Vivitri D. , Stephanie Filia , Laksitorini Marlyn D. , Kuczera Krzysztof , Siahaan Teruna J.
Published: June 2024

Aim: This study was aimed at finding the binding site on the human E-cadherin for Ala-Asp-Thr Cyclic 5 (ADTC5), ADTC7, and ADTC9 peptides as blood-brain barrier modulator (BBBM) for determining their mechanism of action in modulating the blood-brain barrier (BBB).
Methods: ADTC7 and ADTC9 were derivatives of ADTC5 where the Val6 residue in ADTC5 was replaced by Glu6 and Tyr6 residues, respectively. The binding properties of ADTC5, ADTC7, and ADTC9 to the extracellular-1 (EC1) domain of E-cadherin were evaluated using chemical shift perturbation (CSP) method in the two dimensional (2D) 1H-15N-heteronuclear single quantum coherence (HSQC) nuclear magnetic resonance (NMR) spectroscopy. Molecular docking experiments were used to determine the binding sites of these peptides to the EC1 domain of E-cadherin.
Results: This study indicates that ADTC5 has the highest binding affinity to the EC1 domain of E-cadherin compared to ADTC7 and ADTC9, suggesting the importance of the Val6 residue as shown in our previous in vitro study. All three peptides have a similar binding site at the hydrophobic binding pocket where the domain swapping occurs. ADTC5 has a higher overlapping binding site with ADTC7 than that of ADTC9. Binding of ADTC5 on the EC1 domain influences the conformation of the EC1 C-terminal tail.
Conclusions: These peptides bind the domain swapping region of the EC1 domain to inhibit the trans-cadherin interaction that creates intercellular junction modulation to increase the BBB paracellular porosity.
Current status of molecular diagnostics for lung cancer
Authors: Imyanitov Evgeny N. , Preobrazhenskaya Elena V. , Orlov Sergey V.
Published: June 2024

The management of lung cancer (LC) requires the analysis of a diverse spectrum of molecular targets, including kinase activating mutations in EGFR, ERBB2 (HER2), BRAF and MET oncogenes, KRAS G12C substitutions, and ALK, ROS1, RET and NTRK1-3 gene fusions. Administration of immune checkpoint inhibitors (ICIs) is based on the immunohistochemical (IHC) analysis of PD-L1 expression and determination of tumor mutation burden (TMB). Clinical characteristics of the patients, particularly age, gender and smoking history, significantly influence the probability of finding the above targets: for example, LC in young patients is characterized by high frequency of kinase gene rearrangements, while heavy smokers often have KRAS G12C mutations and/or high TMB. Proper selection of first-line therapy influences overall treatment outcomes, therefore, the majority of these tests need to be completed within no more than 10 working days. Activating events in MAPK signaling pathway are mutually exclusive, hence, fast single-gene testing remains an option for some laboratories. RNA next-generation sequencing (NGS) is capable of detecting the entire repertoire of druggable gene alterations, therefore it is gradually becoming a dominating technology in LC molecular diagnosis.
A művészi újrajátszás terei, helyei és tájai
Authors: Süli-Zakar Szabolcs
Published: June 2024

The paper explores artistic re-enactments through spatial perspectives, rather than temporal ones. Drawing on spatial theories and the “spatial turn” to shed light on the artistic process I analyse four moving image works in the exhibition Re:Re, The Art of Re-enactment, Artistic Re-enactments in MODEM. In the case of Jeremy Deller’s re-enactment of the Battle of Orgreave, for example, the artist transforms the space of power into a place with a unique identity, using its specific history to evoke and dissolve the trauma of the original event. In Irina Botea Bucan’s work, Auditions for a Revolution, temporal and spatial displacement reenacts the original shots and events, revealing the spatial aspects of artistic re-enactment. Lola Arias’s documentary theatre production, Audition for a Demonstration, contextualizes social upheavals, evoking the past to reveal changes in social norms, values, and perspectives from a spatial aspect. Finally, Andrei Maria by Ingela Johansson is a film essay on Tarkovsky’s the Sacrifice, where the airy space of atmosphere and the places of objects floating in space are combined in a montage film.
A város tere és ideje
Authors: Boros Lili
Published: June 2024

In this study I focus on the aesthetics and methods of artistic reenactments and try to interpret and emphasize the urban background of those artistic reenactments which problematize culturally significant themes, such as the post-Soviet state. I argue that one of the most characteristic elements of literary repetition is space in novels, more precisely Mikhail Bakhtin’s concept of the chronotope and the culture-forming character of the city. I also analyse the distinction and characteristics of (re)enactments and fictitious reenactments. However, in this paper I do not aim to give an overview of art history, but rather to discuss the interpretation experiment that appears in a less prominent way in the international and Hungarian literature on artistic reenactments: definition of parallelism as a text organizing element in literature and the significance of repeating spatial situations. I apply this approach in the interpretation of artistic (re)enactments related to the Soviet and Russian past and present, and to the city of Saint-Petersburg.
Összetett médiumhasználat az alkotói gyakorlatban
Authors: Pettendi Szabó Péter
Published: June 2024

This article delves into the intricate nature of creative practice and its associated media usage. I substantiate theoretical approaches with practical examples, drawing primarily from my own work and experience. e analysis covers various aspects, such as the medium as message, the exhibition as a medium, and the role of structure, in a spatial network that can intersect and overlap. e article includes examples from my own artistic projects, including documentary photography, and discusses my creative insights on re-enactments. The article emphasizes the pivotal relationship between message and structure in the creative process. It underscores that combining different media can lead to deeper understanding and emotional connections with the audience.
Penerapan Green Ticketing Wisata Lokal Mohinggito Sebagai Upaya Peningkatan Pelestarian Lingkungan
Authors: Taruh Victorson
Published: June 2024

Pulau Mohinggito salah satunya adalah wisata lokal potensial yang dikelola oleh salah satu warga Gorontalo Utara. Pulau Mohinggito termasuk dalam wilayah desa Moluo Kecamatan Kwandang Kabupaten Gorontalo Utara yang merupakan destinasi wisata pulau yang sudah banyak dilirik dan dikunjungi oleh para wisatawan khususnya lokal. Berdasarkan hasil observasi dilapangan ditemukan beberapa permasalahan yaitu pertama pada wisata lokal pulau Mohinggito untuk sistem tiket yang diterapkan masih konvensional dalam hal ini hanya berupa kertas sebagai tanda bayar dan dipakai menjadi bukti masuk. Kedua pengelolaan sampah dan kegiatan pelestarian lingkungan masih kurang serta terdapat beberapa titik menjadi penumpukan sampah. Ketiga menurunnnya tingkat kesadaran para wisatawan dalam menjaga kelestarian lingkungan, hal ini terlihat masih ada wisatawan yang sembarangan membuang sampah. Tujuan kegiatan pengabdian ini adalah memberikan kontribusi positif kepada masyarakat dan pengelola wisata terkait penerapan Green ticketing. Metode pelaksanaan pengabdian ini yaitu terbagi menjadi dua persiapan dan pelaksanaan melalui pemberian materi dan diskusi dua arah. Hasil pengabdian menunjukkan bahwa penerapan konsep Green ticketing sangat penting demi keberlanjutan kegiatan wisata, dimana ini merupakan langkah atau upaya untuk menjaga kelestarian lingkungan sekitar wisata. Sehingga implikasi dari hasil pengabdian ini sangat penting bagi pemerintah daerah dan pengelola wisata Pulau Mohinggito kedepan ketika akan menerapkan Green ticketing.
Interkulturelle Professionalisierung durch selbstgeleitete und kooperative E-Portfolio-Arbeit in allen Mobilitätsphasen
Authors: Fett Anne , Grüttner Peter , Reichelt Elena , Sträßer Norman
Published: June 2024

Das Zertifikatsangebot LAIK (Lehramt Interkulturell), das im Rahmen des DAAD-Projekts “Internationalisierung der Lehrer*innenbildung” entwickelt und implementiert wurde, bietet Lehramtsstudierenden ein neuartiges strukturiertes Reflexionsangebot für die Vorbereitung, Begleitung und Nachbereitung von Auslandsaufenthalten (Studium, Praktikum, kombinierte Aufenthalte): Das auf der ursprünglich quelloffenen Lernumgebung Mahara basierende Tool, welches durch einen Pilotdurchgang auf die Bedürfnisse Lehramtsstudieren-der zugeschnitten wurde, ermöglicht diesen die Arbeit an einem E-Portfolio während aller Mobilitätsphasen. Durch LAIK treten Studierende in einen Prozess interkultureller Selbstreflexion ein, der sowohl im sicheren, privaten Raum als auch in kollegialer Fallberatung mit anderen Studierenden (Tandem-Feedback) erfolgt – und in den Mentor*innen der Heimatuniversität sowie Betreuende im Ausland digital eingebunden werden. Dieser Prozess fördert ein Bewusstsein für die eigenen kulturellen Prägungen und verdeutlicht die Mehrdimensionalität von Unterricht in interkulturellem Kontext. Auch während des Aufenthalts entwickeltes Material kann geteilt und mit Studierenden sowie Mentor*innen reflektiert werden. Die interkulturelle Professionalisierung Lehramtsstudierender erfolgt innerhalb von LAIK eingebettet in einen gleichsam selbstgeleiteten und begleiteten Reflexionsprozess, der die “Wegmarken” von Digitalisierung, Reflexion, Kooperation und Mobilität integriert und ein Best-Practice-Beispiel zukunftsfähiger Kompetenzentwicklung darstellt.
REPRESENTACIONES DE LA MATERNIDAD EN EL MAESTRANTE (1893) DE ARMANDO PALACIO VALDÉS
Authors: Gomis-Izquierdo Vicente
Published: June 2024

Este trabajo analiza la novela El maestrante (1893) de Armando Palacio Valdés para explorar cómo muestra la figura de la madre y cómo esa representación es reflejo de las ansiedades sobre la maternidad que existían a finales del siglo xix en España. Este análisis se realiza a través de las diferentes figuras maternas que aparecen en el texto, desde madres biológicas a putativas o adoptivas, y especialmente observando la transformación de Amalia en una “madre monstruosa.” Se explora esta idea en conjunción con otros textos contemporáneos de Valdés como los discursos médicos de los doctores Encinas y Pulido, o autoras como Concepción Arenal o Carmen de Burgos, entre otras. Además, se usan textos de críticas como Jo Labanyi, Eva María Morata, Leigh Mercer o Teresa Gómez Trueba. La combinación de textos ayuda a formar una idea de conjunto sobre la percepción de la maternidad y su importancia en la sociedad burguesa española del siglo xix y su representación en la literatura realista y naturalista.
NACIÓN O BARBARIE EN LOS CUENTOS FANTÁSTICOS DE JUAN MONTALVO
Authors: Rodrigo Mendizábal Iván Fernando
Published: June 2024

La literatura fantástica con rasgos góticos fue iniciada en Ecuador por Juan Montalvo hacia 1858. Sus cuentos, dispersos en sus revistas y periódicos, no solo son la demostración de su habilidad de narrar, tomando en cuenta la estética de los cultores del romanticismo oscuro, sino también implican temáticas relacionadas con la realidad del país, en concordancia con el trabajo crítico que realizaba mediante ensayos y declaraciones. Es así como, anclándose en las ideas liberales, y siguiendo el espíritu de un moralista, sus cuentos traducen inquietudes inherentes a la constitución de la nación en momentos en que el conservadurismo imperaba y una tendencia progresista se iba construyendo orientada hacia el cosmopolitismo, pese a los problemas de gobernabilidad. Los cuentos fantásticos de Montalvo, en este sentido, muestran la tensión de nación o barbarie –como paráfrasis de la tesis de civilización o barbarie–,haciendo aparecer seres anómalos o con patologías, hechos relacionados con el horror, espíritus amenazantes, entre otros. Montalvo, situado en la literatura fantástica, hace disección ideológica, satiriza, lleva a que el lector se forme una idea de la realidad, además postula una idea de nación distinta.
REALISM AND THE FANTASTIC
Authors: Ginger Andrew
Published: June 2024

Nineteenth-century Spanish literature was characterized by decades-long continuities stemming from revolutionary political and aesthetic impulses. The fantastic was central to these continuities. However, in advocating for “Realism”, Galdós and Pardo Bazán successfully rewrote literary history to their own ends, occluding swathes of inventive nineteenth-century literature and ideology, deemed extravagant and lacking serenity. The great deletion included the fantastic, along with a spectrum of literary and political explorations of imaginative freedom to which it belonged. Too often taken as near-literal accounts, Galdós and Pardo Bazán’s essays were polemical interventions in long-standing debates. Their “Realism” primarily aimed for a new balance of serenity and fantasía, a quest shared with literary writers, historians, aspects of “realist” practice, as exemplified in El amigo Manso, may seem perplexing.But, re-situated amid nineteenth-century debates, Spanish “Realism” is an attempt, not to suppress either fantasía or the fantastic but to re-invent them, and so re-imagine Spanish and imperial history and society.
Caracterización de las propiedades mecánicas del bioplástico de almidón de plátano (Musa paradisiaca L.) y compuestos celulósicos de café (Coffea arabica L.)
Authors: Cabrejos Castillo Karla Gretel , Maluquis Sánchez Jackeline Elizabeth , Díaz Ruiz Adán , Minchán Velayarce Hans Himbler
Published: June 2024

The objective was to characterize the mechanical properties of the bioplastic obtained with banana starch (Musa paradisiaca L.) and cellulosic compounds from coffee husks (Coffea arabica L.).. Starch was used in concentrations of 9, 12 and 15% and cellulose in concentrations of 2, 4 and 6%, mixing them with glycerin, acetic acid, calcium chloride and distilled water. The tensile, elongation and bending mechanical properties were characterized. The bioplastic with the highest traction was the F9 formulation (15% starch, 6% cellulose) with 2.23 N ± 0.242 and the F1 formulation (9% starch, 2% cellulose) with the lowest traction was the F1 formulation (9% starch, 2% cellulose) with 0.17 N ± 0.069; Formulation F7 (15% starch, 2% cellulose) presented the greatest elongation of 10.3 cm ± 1.528 and greatest flexion of 13.3 cm ± 1.155; and formulation F3 (9% starch, 6% cellulose) had the lowest elongation of 3.33 cm ± 0.577 and the lowest bending of 9.33 cm ± 1.155. The increase in starch concentration favors traction, elongation and bending, the increase in cellulose concentration only favors traction, disfavors elongation and is indifferent to bending.
PERANCANGAN ALAT PENGEPRESAN BAGLOG JAMUR TIRAM YANG ERGONOMIS GUNA MENGURANGI RISIKO CIDERA OTOT DAN MENINGKATKAN PRODUKTIVITAS KERJA
Authors: Mela Arij Basmin Basmala
Published: June 2024

Dalam kasus kondisi kerja duduk membungkuk, skor atau bagian tubuh yang paling sering mengalami cidera adalah leher, bahu, punggung, lengan, pinggang, paha, dan betis. Oleh karena itu, desainer harus membuat produk baru atau mengubah yang sudah ada. Berdasarkan hasil penelitian yang telah dilakukan, dapat disimpulkan bahwa ada delapan fitur yang diinginkan pelanggan perusahaan alat jamur tiram rumahan Pak Heru, yaitu pelanggan paling tertarik dengan alat jamur tiram home industry Pak Heru karena dimensinya yang sedang dan unik, desain bentuknya yang kokoh, bahannya yang terbuat dari besi, kapasitas produksi 200-500 baglog per hari, tekanan pada kepadatan baglog, fungsi utama alat bantu kerja, dan fungsi tambahan corong.
Kata kunci : Nordic Body Map, REBA, QFD, Perancangan Alat, Produktivitas
Foreign directors, foreign ownership, and carbon emission disclosure: Evidence from Indonesia environmentally sensitive companies
Authors: Wulan Diajeng Fitri
Published: June 2024

Business organizations were increasingly being held accountable for their social and environmental impacts. Disclosure of carbon emissions is an issue that is starting to develop in various countries, including Indonesia, related to climate change's effects on organizations' sustainability. National governments and non-governmental organizations (NGOs) needed to take action to urge companies to reduce carbon emissions, one of which is full disclosure of their carbon emissions. This study aimed to see whether knowing the presence of foreign directors, foreign commissioners, and foreign ownership affects the disclosure of carbon emissions. This study also used three control variables: Company Size, ROA, and DER. The samples of this research were companies listed on the IDX that are sensitive to the environment from 2019 to 2021, which issued a Sustainability Report resulting in a total of 41 companies. The test was carried out by performing multiple regression tests. The results showed that foreign commissioners, company size, and DER significantly influenced the disclosure of carbon emissions. Therefore, managers should consider balancing between foreign and local commissioners to benefit from a rich, heterogeneous resource encompassing the various merits of both types of directors, with particular emphasis on foreign commissioners' international exposure and experience.
Profit management from a legal and accounting perspective
Authors: Sari Maya Macia , Sakdiah Sakdiah , Trifana Novania , Nuraisyah Julia , Sari Dwi Kumala
Published: June 2024

This study aimed to understand and analyze Profit Management from legal and accounting perspectives. To obtain data related to these variables, researchers made indirect observations. The data used in this study were secondary data, collected through intermediary sources (obtained and recorded by other parties). Secondary data typically included evidence, records, or historical reports compiled in published and unpublished archives (documentary data). The research employed action research, with data collection conducted primarily through intermediary media. Based on the results of this study, the effectiveness of law and accounting was shown to have had a positive and significant impact on profit management within a company. In the case study of banking services, where conventional bank interest was considered usury, financial institutions were required to adhere to Sharia foundations. The values of Sharia law served as a fundamental framework in the societal and national life systems, with Islamic law governing as a rule of life. The pillars and legal conditions of contracts in Sharia were akin to the legal conditions in principle.
Income, tax knowledge, and tax incentives impact on MSME tax compliance in COVID-19
Authors: Thelmalia Ni Luh Putu Western , Pemayun Gde Putra , Mimaki Caren Angellina
Published: June 2024

This study aimed to determine the effect of income level, tax knowledge, and the application of tax incentive policies partially on taxpayer compliance. The research method used was quantitative. The population in this study comprised taxpayers who had a business type of UMKM registered at KPP Pratama Gianyar, and the sample used consisted of 100 people. The data analysis techniques included the Validity Test, Reliability Test, Classical Assumption Test, Multiple Linear Regression Analysis, Determination Coefficient Test, F Test, and t-test. From the results of the study, the following were obtained: (1) The level of income had a significant positive effect on taxpayer compliance, where the t-coefficient value was 3.598, the regression coefficient value was 0.364, and the significance was 0.001. (2) Tax knowledge had a significant positive effect on taxpayer compliance, with the t-coefficient value being 4.339, the regression coefficient value 0.335, and the significance 0.000. (3) The application of tax incentive policies had a significant positive effect on taxpayer compliance, with the t-coefficient value being 3.159, the regression coefficient value 0.210, and the significance 0.002. The suggestion in this study was that the Gianyar KPP Pratama should provide a tax burden that was in accordance with the taxpayer's business income and routinely provide tax socialization to increase taxpayer knowledge. Additionally, the Gianyar KPP Pratama should provide fair tax incentives to all taxpayers who meet the conditions for receiving them.
Comparison of financial performance of LPD Pakraman Singapadu before and after COVID-19
Authors: Loceng I Gusti Ngurah Bayu Danuartha , Suryanata I Gusti Ngurah Putra , Sumarningsih Ni Made
Published: June 2024

This study utilized a mixed-methods approach to evaluate the financial performance of LPD Pakraman Singapadu Village before and after the COVID-19 pandemic, specifically from July 2019 to July 2020. Quantitative data was gathered from financial documents, including income statements and balance sheets, to compare financial metrics across the two periods. Qualitative data was obtained through semi-structured interviews with key stakeholders, including LPD staff and local business owners, to gain insights into the impact of the pandemic on financial performance. Observational methods were also employed to understand the operational changes and challenges faced by the LPD during this period. Financial documents were reviewed to extract relevant financial indicators such as revenue, expenses, and profit figures, with the 2019 financial performance, which showed a profit of Rp. 477,422,463, serving as a baseline for comparison against the 2020 performance, which saw a decrease in profit to Rp. 303,884,859 due to the pandemic's onset in March 2020. Interviews were recorded and transcribed verbatim, followed by thematic analysis to identify key themes related to the pandemic's impact on financial performance and business operations. Observations provided additional context to the quantitative data, highlighting how the pandemic influenced operational dynamics and financial outcomes. All collected data was analyzed using appropriate statistical and thematic techniques to ensure the robustness and reliability of the findings, enabling a thorough examination of the changes in the financial performance of LPD Pakraman Singapadu Village in the context of the COVID-19 pandemic.
The influence of anxiety and depressive disorders on the development of resistant arterial hypertension
Authors: Pchelenok Ju. V. , Fomicheva A. V. , Kanaeva M. , Rodionov A. V. , Tolokonin A. O. , Volel B. A.
Published: June 2024

The problem of comorbidity of cardiovascular diseases (CVD) and anxiety-depressive disorders is actively discussed in modern scientific literature. Taking into account the widespread prevalence of anxiety and depressive disorders in the population, their negative impact on the quality of life and functioning of patients, prerequisites are accumulating for the diagnosis and treatment of these conditions by non-psychiatric doctors. The review presents current data on risk factors, relationships and principles for diagnosing resistant arterial hypertension (RAH) and anxiety-depressive disorders. The prevalence of resistant arterial hypertension is about 10–20 %, with a significant proportion of cases accounting for secondary arterial hypertension and pseudoresistance. The incidence of anxiety and depressive disorders in patients with arterial hypertension is 42 % and 52 %, respectively. The prevalence of anxiety and depressive disorders in RAH is 36.8 %. Such comorbidity contributes to the progression of PAH, worsens the patient’s prognosis, and reduces adherence to therapy. Given the close relationship between psychoemotional factors and CVD, patients with RAH are advised to undergo screening for anxiety and depression.
Social Media, New Platforms, and Women Empowerment: A Sociological Study in Bangladesh
Authors: Koli Kamrunahar
Published: June 2024

This study focuses on the empowerment of women through the utilization of social media. Social networking, which is arguably the most significant technical advancement of recent years, has experienced a surge in popularity across the country. Social media has rapidly emerged as a prevailing means of professional and personal communication. It is indispensable in contemporary society because it facilitates the dissemination of ideas, thoughts, and opinions. Additionally, it can be utilized to endorse businesses, organizations, and movements while being up-to-date. The main objective of this paper was to investigate the influence that social media platforms have on the empowerment of women. The study sought to assess women of a certain age in order to identify how social media impacts women's empowerment. The research was conducted with a suitable theoretical framework in mind. As part of the research, both quantitative and qualitative methodologies were employed. An online survey was exploited to gather data from 120 individuals who engage in online business using social media platforms. In addition, case studies were conducted on a sample of 10 individuals to gain a comprehensive understanding and achieve the intended outcome. Research reveals that the COVID-19 pandemic has brought about substantial transformations in the contemporary condition of women's empowerment. Following the COVID pandemic, there is a swift change in the circumstances, and women have shifted from being homemakers to becoming powerful earners by leveraging social media platforms. Now that they are contributing financially, they are able to have a say in family decisions that were previously out of their hands.
Az első rendőrségitörvény-javaslat
Authors: Sallai János
Published: June 2024

The establishment of the Hungarian public administration was marked by the Austro-Hungarian Compromise of 1867, after which the establishment of the Hungarian state police came to the fore. In 1848, Bertalan Szemere entrusted Paul Hajnik with the establishment of a national police force, in 1873 a state police force in the capital, in 1903 a border police force, and in 1918 the Wekerle police bill. At the beginning of this process, the Police Act proposal of 1871 by Pál Csepy, which clearly calls for the establishment of a national police force, was drafted and survives.
Aim: The aim of the study is to present the circumstances and content of the first Police Act proposal, from the beginning of the police nationalisation process.
Methodology: The author of the article examines the beginning of the nationalisation of the police, the first police act and its content by searching and analysing the literature on policing around the Compromise.
Findings: The Compromise of 1867 also provided opportunities for the restoration of autonomy in the field of police and policing. After Habsburg rule, the following three ideas for future policing emerged: strengthening the old Pandour world, organising a military-style gendarmerie or a civilian-style police force. After a professional debate in the first police journal, the participants in the first Congress of Police Chiefs advocated a national police force, for which a high-quality police act was drafted and submitted to the political leadership.
Value: The nationalisation process of the police started in 1848 and lasted until 1920. In the preceding period, a law on the field police was passed in 1840, and after 1872 laws were passed on the metropolitan police, the border police, the police of Fiume and the gendarmerie. Comparing the 1871 Police Act with the laws on the above subjects, it can be seen that the latter was comprehensive, covering all aspects of policing, and proved to be valuable and timeless.
FAKTOR-FAKTOR YANG MEMPENGARUHI PERSEPSI MASYARAKAT MENGENAI VAKSINASI COVID-19
Authors: Natapraja R. Bayu Kusumah , Tresnawan Teten
Published: June 2024

Pada tanggal 30 Januari 2020 WHO menetapkan Covid-19 sebagai pandemik. 8 bulan kemudian kasus Covid-19 hampir menyerang seluruh dunia. Salah satu upaya yang dilakukan pemerintah yaitu dengan cara 3M (memakai masker, mencuci tangan dan menjauhi kerumunan/mobilisasi), upaya preventifnya yaitu dengan vaksin Covid-19. Tujuan penelitian untuk mengetahui adakah pengaruh faktor perhatian, pengetahuan, status pernikahan, riwayat penyakit, dan riwayat terpapar Covid-19 terhadap persepsi masyarakat mengenai vaksinasi Covid-19. Hasil uji statistik diperoleh nilai p<0,05, sehingga dapat disimpulkan bahwa ada hubungan yang signifikan antara umur, pendidikan, riwayat PTM, riwayat terpapar Covid-19, dan pengetahuan dengan persepsi masyarakat tentang vaksinasi Covid-19, hanya riwayat pernikahan yang tidak hubungan dengan nilai p=0,919 atau >0,05. Simpulan terdapat hubungan antara umur, pendidikan, riwayat PTM, riwayat terpapar Covid-19, dan pengetahuan dengan persepsi masyarakat tentang vaksinasi Covid-19. Disarankan Pemerintah Desa Cicukang diminta secara aktif untuk terus bersosialisasi kepada masyarakat untuk memberikan informasi, baik itu tentang upaya agar Covid-19 tidak lagi mengalami peningkatan kasus aktif dan informasi tentang vaksin agar masyarakat mau dan ingin segera untuk divaksin.Kata kunci: Persepsi; Vaksin; Covid-19 AbstractOn January 30, 2020 WHO declared Covid-19 a pandemic. 8 months later Covid-19 cases almost attacked the whole world. One of the efforts made by the government is by 3M (wearing masks, washing hands and staying away from crowds / mobilization), preventive efforts are the Covid-19 vaccine. The purpose of the study was to determine whether there is an influence of attention factors, knowledge, marital status, history of illness, and history of exposure to Covid-19 on people's perceptions of Covid-19 vaccination. The statistical test results obtained a p value <0.05, so it can be concluded that there is a significant relationship between age, education, history of NCD, history of exposure to Covid-19, and knowledge with public perceptions of Covid-19 vaccination, only marriage history has no relationship with a p value = 0.919 or >0.05. It is concluded that there is a relationship between age, education, history of NCD, history of exposure to Covid-19, and knowledge with community perception of Covid-19 vaccination. It is recommended that the Cicukang Village Government be actively asked to continue to socialize with the community to provide information, both about efforts so that Covid-19 no longer has an increase in active cases and information about vaccines so that people want and want to be vaccinated immediately.Keywords: Perception; Vaccine; Covid-19
Formulation and Evaluation of niosome containing Glycolic acid for acne dark spots
Authors: Pathak Apoorvi , Mishra Namrata , Bhattacharya Vijeta
Published: June 2024

A Non-Ionic surfactant-based vesicles, otherwise called niosomes, stand outenough to be noticed in drug fields because of their amazing conduct in typifying both hydrophilic and hydrophobic specialists. As of late, it has been found that these vesicles can work on the bioavailability of medications, and may work as another technique for conveyinga few normal of remedial specialists, for example, chemical and protein drugs and gene materials with low poisonousness and wanted to focus on efficiency. Compared with liposomes, niosomes are significantly steadier during the plan interaction and storage. The required pharmacokinetic properties can be accomplished by streamlining part sort by surface modification. This original conveyance framework is likewise simple to get ready and scale up with low creation costs. In this thesis, we sum up the formulation, method, and characterization of niosome and its applications in skin diseases like Acne dark spots. Niosomal gel containing drug is being formulate for effective delivery of drug into the skin as gel has good absorption rate. The method and evaluations of gel is we sum up in this thesis.
High-velocity Blue-shifted Fe xxv Heα Line during a Superflare of the RS Canum Venaticorum–type Star IM Peg
Authors: Inoue Shun , Iwakiri Wataru Buz , Enoto Teruaki , Uchida Hiroyuki , Kurihara Miki , Tsujimoto Masahiro , Notsu Yuta , Hamaguchi Kenji , Gendreau Keith , Arzoumanian Zaven , Tsuru Takeshi Go
Published: June 2024

The Monitor of All-sky X-ray Image (MAXI) detected a superflare, releasing 5 × 1037 erg in 2−10 keV, of the RS CVn-type star IM Peg at 10:41 UT on 2023 July 23 with its Gas Slit Camera (2−30 keV). We conducted X-ray follow-up observations of the superflare with the Neutron Star Interior Composition Explorer (NICER; 0.2−12 keV) starting at 16:52 UT on July 23 until 06:00 UT on August 2. NICER X-ray spectra clearly showed emission lines of the Fe xxv Heα and Fe xxvi Lyα for ∼1.5 days since the MAXI detection. The Fe XXV Heα line was blueshifted with its maximum Doppler velocity reaching −2200 ± 600 km s−1, suggesting an upward-moving plasma during the flare, such as a coronal mass ejection (CME) and/or chromospheric evaporation. This is the first case that the Fe xxv Heα line is blueshifted during a stellar flare, and its velocity overwhelmingly exceeds the escape velocity of the star (−230 km s−1). One hour before the most pronounced blueshift detection, a signature of the reheating of the flare plasma was observed. We discuss the origin of the blueshift, a CME, or high-velocity chromospheric evaporation.
A trawl collected dataset of Johnius (Actinopterygii, Sciaenidae) species in central-western Taiwanese waters
Authors: Hanafi Norhafiz , Chen Meng-Hsien , Yang Ming-Che , Lai Chien-Cheng , Chang Chih-Wei
Published: June 2024

Sciaenidae is one of the most important coastal fisheries in Taiwan, both in production and economic value. It is also significant as the main targetted diet of Chinese white dolphins, Sousa chinensis, especially for the genus Johnius, such as J. taiwanensis, J. belangerii and J. distinctus, which is primarily found in central-western Taiwan coastal waters. Despite an abundance of Johnius species occurrences reported in the Global Biodiversity Information Facility (GBIF) and the Taiwan Biodiversity Information Facility (TaiBIF) data portals (Mozambique, Australia, Taiwan, Korea, India, Indonesia, South Africa, Pakistan, Vietnam and China), there are no specific datasets that properly document the regional distribution of this genus, especially in Taiwanese waters. Thus, this paper describes a dataset of genus Johnius occurrences in waters on the central-western coast of Taiwan. The data collection for the present study was conducted from 2009 until 2020 and comprised 62 sampling events and 133 occurrence records. All fish specimens were collected by trawling in Miaoli, Changhwa and Yunlin Counties, Taiwan and brought back to the lab for identification, individual number count and body weight measurement. These processing data have been integrated and established in the Taiwan Fish Database and published in GBIF. This dataset contains six Johnius species and 2,566 specimens, making it comprehensive Johnius fish fauna and spatial distributional data on the coastal habitat in central-western Taiwanese waters.

This dataset contains 133 occurrence records of Johnius species (Sciaenidae) with 2,566 specimens, making it the most extensive public dataset of Johnius distribution records in Taiwan. The publication of this dataset through the TaiBIF and GBIF dataset platforms demonstrated that the number of Johnius spatial and temporal records in Taiwan waters is influenced by the topographical structure of the Changyun Rise (CYR) in combination with the cold current of the China Coastal currents and bound with the warm currents of the Kuroshio and the South China Sea on the central-western coast of Taiwan. The data serve as the foundation for understanding the biogeography and Johnius species ecology in Taiwan's coastal waters, which present a 2°C water temperature difference split at the CYR.
Preparation and characterization of new silica-based heterofunctional biocatalysts utilizing low-cost lipase Eversa® Transform 2.0 and evaluation of their catalytic performance in isoamyl esters production from Moringa oleifera Lam oil
Authors: Carvalho Wagner C. A. , Freitas Rayane A. S. , Barbosa Milson S. , Paula Ariela V. , Pereira Ernandes B. , Mendes Adriano A. , Franceschi Elton , Soares Cleide M. F.
Published: June 2024

Due to the need to replace lubricants derived from polluting processes and inputs, bioprocesses and raw materials such as vegetable oils have been used for the production of biolubricants. In this study, the synthesis of esters with lubricating potential was conducted through enzymatic hydroesterification. For complete hydrolysis of Moringa oleifera Lam. seed oil (MOSO), Candida rugosa lipase was applied under conditions already established in the literature. Subsequently, the synthesis of esters of industrial interest was carried out through esterification using a lipase (Eversa Transform 2.0 (ET2.0)) immobilized by different functional groups on heterofunctional silica-based supports: epoxy-silica (Epx), glyoxyl-silica (Gly), and amino-glutaraldehyde-silica (AmG). Two drying pre-treatment techniques were used to improve the immobilization yield of the ET2.0 lipase on different pre-treated supports: evaporation in a drying oven (with improvements ranging from 15% to 46%) and pressure difference in a desiccator (with improvements ranging from 24% to 43%). The immobilizing supports and biocatalysts were characterized to verify their morphologies, structures, and topographies. Deconvolution was performed to evaluate the secondary structure of the ET2.0 lipase and showed increases in the α-helix and β-sheet regions for all biocatalysts after the immobilization process. In a solvent-free medium, the AmG-70h support performed best in the esterification reaction, at around 90% conversion, with a load of 1.65 mg of protein in the reaction. Moreover, it obtained a productivity around 4.45 times that of free ET2.0 lipase, maintaining its original activity until the fourth cycle. This work offers the opportunity to understand and synthesize new biocatalysts with a low-cost genetically modified lipase using a renewable raw material, opening new possibilities to fill gaps that still exist in the use of lipases for biolubricant production.
Inversion formulas for space-fractional Bessel heat diffusion through Tikhonov regularization
Authors: Bouzeffour Fethi
Published: June 2024

This article explores the generalized Gauss-Weierstrass transform associated with the space-fractional Bessel diffusion equation. Explicit inversion formulae for this transform are developed using best approximation methods and reproducing kernel theory. To address the inherent ill-posedness of this transform, Tikhonov regularization is implemented. Furthermore, the convergence rate of the regularized solutions is rigorously established.