bluuebunny/crossref_metadata_2025 huggingface dataset:
Elementary Engineering as a Synergistic Site for Disciplinary and Linguistic Learning in an Urban Classroom
Authors: Paugh Patricia , Wendell Kristen , Wright Christopher
Published: July 2018

This case study of new English-language learners in an urban elementary U.S. classroom addresses the synergy between disciplinary language and science, technology, engineering, math (STEM) learning. Social semiotic theory frames the discourse demands related to engineering design and the active use of discursive resources in students’ responses to these demands. Discourse analysis of students’ interactions and writing provides a fine-grained view of “language in use” within an engineering design space where students demonstrated linguistic agency and productive engineering accomplishments. The case provides insights for educators who seek to optimize the integration of the language of STEM with culturally and linguistically responsive engineering education.
The importance of oracle rejoining in the study of ancient characters and the history of the Shang Dynasty
Authors: Zhang Weijie
Published: July 2018

From the beginning of the unearthing of oracle bones in Anyang Henan, traditional descriptions of the ancient history of China have been gradually modified. It is regrettable that the disaster of non-scientific excavations and long-distance transit happened at almost the same time. From knowing the history of the damage to the oracle bones, we can then understand how important the recovery work is. The rejoining work began early in the 20th century, and many scholars have contributed to the related work. The seven examples in this article present multiple values regarding not only recovering the broken oracle bones to their original state, but also ‘highlighting the particular phenomenon of culture’, ‘getting the real recovery of inscriptions’, and ‘verifying the authenticity of documents’. This speaks well of the important rejoining work which benefits the study of ancient characters and Yin Shang history. After all, to use the oracles as a tool to study ancient characters and history, we should first undertake rejoining and restore them to their original appearance.
清华简《厚父》研读札记
Authors: 刘光胜
Published: July 2018

清华简《厚父》 “[Formula: see text]” 读为 “劼”, “[Formula: see text]” 训读为 “绩” 。劼绩, 意为勤勉的业绩, 指大禹纾解水患, 工作艰辛而言。夏、周关系亲密, 周人以夏的继承者自居, 所以称大禹为 “前文人” 。厚父高祖是夏代的辅政大臣, 一人同时为臣下侍奉过夏代的 “三后”, 则 “三后” 必然是前后相继的三位君王。孔甲与禹的在位时间相差约三百年, 厚父的高祖肯定不能同时侍奉此二人的, 因此笔者怀疑孔甲不是《厚父》时王所称的 “三后” 之一。
Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission
Authors: Vasu Sumithira , Kohlschmidt Jessica , Mrózek Krzysztof , Eisfeld Ann-Kathrin , Nicolet Deedra , Sterling Lisa J. , Becker Heiko , Metzeler Klaus H. , Papaioannou Dimitrios , Powell Bayard L. , Kolitz Jonathan E. , Moore Joseph O. , Baer Maria R. , Roboz Gail J. , Stone Richard M. , Byrd John C. , Carroll Andrew J. , Bloomfield Clara D.
Published: July 2018

Key Points

Only 16.6% of patients aged <60 years and 2.4% aged ≥60 years treated with chemotherapy are disease-free at 10 years after diagnosis. Ten-year disease-free survivors were mostly diagnosed with core-binding factor AML with t(8;21) or inv(16), or had a normal karyotype.
Deserving poor and the desirability of a minimum wage
Authors: Blumkin Tomer , Danziger Leif
Published: July 2018

This paper provides a normative justification for the use of a minimum wage as a redistributive tool in a competitive labor market. We show that a government interested in improving the wellbeing of the deserving poor, while being less concerned with their undeserving counterparts, can use a minimum wage to enhance the efficiency of the tax-and-transfer system in attaining this goal.
Absence of cerebrospinal fluid antineuronal antibodies in schizophrenia spectrum disorders – CORRIGENDUM
Authors: Oviedo-Salcedo Tatiana , de Witte Lot , Kümpfel Tania , Kahn René S. , Falkai Peter , Eichhorn Peter , Luykx Jurjen , Hasan Alkomiet
Published: July 2018

This notice describes a correction to the above mentioned paper.
Use of Laryngeal Mask Airway to Preoxygenate and Ventilate Through a Laryngeal Stoma in a Patient Undergoing General Anesthesia: A Case Report
Authors: Evans Trip , Hanna Mark , Hafez Osama , Patel Sephalie Y.
Published: July 2018

The use of the laryngeal mask airways is well established in routine and emergency airway management. Due to its traditional use as a supraglottic airway, it is often overlooked in patients with abnormal airway anatomy such as tracheostomies and laryngeal stomas. We present the unique method of using the laryngeal mask airways externally to facilitate preoxygenation and ventilation in a patient with a laryngeal stoma.
Novel Association of Juvenile Polyposis Syndrome With Atrial Septal Aneurysm and Patent Foramen Ovale: A Case Report
Authors: Bruceta Melanio , De Souza Luisa , Carr Zyad , Bonavia Anthony , Karamchandani Kunal
Published: July 2018

Juvenile polyposis syndrome is an autosomal-dominant disorder characterized by the presence of hundreds of gastrointestinal polyps. The genes most commonly found are BMPR1A and SMAD4. The latter has been linked to vascular malformations and hereditary hemorrhagic telangiectasias. We present the case of a young woman diagnosed with juvenile polyposis syndrome and SMAD-4 mutation, who developed embolic strokes from an atrial septal aneurysm and patent foramen ovale. This case highlights the propensity of patients with juvenile polyposis syndrome and SMAD-4 mutations to develop atrial septal aneurysm and patent foramen ovale, and warrants appropriate cardiac workup in at-risk individuals.
Paraplegia After Laparotomy for Large Bowel Obstruction: A Case Report
Authors: Allencherril Ronan , Pally Annie , Allencherril Joseph , Joseph Linda
Published: July 2018

We report persistent postoperative paraplegia on recovery from anesthesia after emergent exploratory laparotomy for large bowel obstruction in a cachectic patient with an abdominal aortic aneurysm. Postoperative cervical, thoracic, and lumbar spine magnetic resonance imaging revealed only cervical spinal stenosis. We hypothesize that intraoperative embolization possibly caused by manipulation of an atherosclerotic aorta, and a brief episode of intraoperative hypotension resulted in spinal cord ischemia. This report highlights the importance of maintaining intraoperative hemodynamic stability and careful handling of the abdominal aorta, especially in underweight patients with an abdominal aortic aneurysm.
Naloxegol to Treat Constipation in a Patient Taking Opioids for Cancer Pain: A Case Report
Authors: Gálvez Rafael , Maire Coralie , Tovar Isabel , Vargas Pilar
Published: July 2018

Opioid-induced constipation (OIC) is a common gastrointestinal adverse effect of opioids, which can severely affect compliance and adherence to pain medication regimens and quality of life. Naloxegol has demonstrated efficacy against OIC in several studies involving patients with nonmalignant chronic pain. Here we report efficacy and tolerability of naloxegol in a 68-year-old patient with metastatic lung cancer and severe pain, treated with opioids, who presented with OIC resistant to traditional measures. Addition of naloxegol produced rapid improvement in his OIC symptoms and no apparent adverse effects while taking extended-release morphine 130 mg orally every 12 hours.
Treatment of Refractory Intraoperative Hypoxemia After Trauma With Venovenous Extracorporeal Membrane Oxygenation: A Case Report
Authors: Louro Jack , Weir John J. , Brozzi Nicolas A. , Dudaryk Roman
Published: July 2018

Extracorporeal membrane oxygenation has emerged as a treatment of choice for refractory hypoxemia in the intensive care unit. Severe hypoxemia unresponsive to conventional lung-protective mechanical ventilation could also occur in the operating room from severe bronchospasm, pulmonary contusions, or acute respiratory distress syndrome. We report a case of acute hypoxic respiratory failure in an adolescent with blunt chest trauma that was successfully managed with the intraoperative initiation of venovenous extracorporeal membrane oxygenation during the initial damage control surgery.
When Guidelines Fail: Euglycemic Diabetic Ketoacidosis After Bariatric Surgery in a Patient Taking a Sodium–Glucose Cotransporter-2 Inhibitor: A Case Report
Authors: Lane Sophia , Paskar David , Hamed Shatha , Goffi Alberto
Published: July 2018

A 42-year-old woman with diabetes mellitus type 2 treated with the sodium–glucose cotransporter-2 inhibitor canagliflozin underwent elective bariatric gastric bypass. The canagliflozin was held for 24 hours preoperatively. She physiologically decompensated on postoperative day 2. Ultimately, she was diagnosed with euglycemic diabetic ketoacidosis that required intensive care management. This diagnosis was challenging to make as the patient never became hyperglycemic. We use this case to discuss the pharmacology and potential risk of perioperative sodium glucose cotransporter-2 inhibitor administration and to advocate for revision of current guidelines regarding the perioperative management of these agents.
Intraoperative Use of Desmopressin for Treatment of Profound Hyponatremia in the Setting of Emergency Surgery: A Case Report
Authors: Watterworth Blake S. , Noorani Robert J.
Published: July 2018

Correction of profound hyponatremia requires careful planning and close monitoring to reduce the risks of neurologic injury. Although there are various suggested treatment strategies in the setting of a medical ward or intensive care unit, reports of intraoperative management to prevent rapid increases in serum sodium are lacking. We present a case of profound hyponatremia of 102 mmol/L in a patient who required emergent operative repair for bowel obstruction. This is the first case to our knowledge that demonstrates a perioperative fluid and desmopressin treatment strategy to prevent overly rapid changes of sodium concentration in a patient with severe hyponatremia.
Spinal Anesthesia for Emergent Abdominal Surgery in a Patient With a Tricuspid Valvectomy: A Case Report
Authors: Harold Katherine Henderson , Webster Michael
Published: July 2018

Tricuspid valvectomy without replacement is an accepted treatment for drug-resistant endocarditis. The current intravenous drug abuse epidemic is leading to more occurrences of right-sided valvular endocarditis. This suggests that the incidence of tricuspid valvectomies may rise. Our academic hospital has seen 3 such patients in the past year alone. We review the implications of this pathophysiology and discuss the anesthetic management of a 33-year-old woman with previous tricuspid valvectomy presenting for emergent abdominal surgery.
PTPα is required for laminin-2-induced Fyn–Akt signaling to drive oligodendrocyte differentiation
Authors: Ly Philip T. T. , Stewart Craig , Pallen Catherine J.
Published: July 2018

Extrinsic signals that regulate oligodendrocyte maturation and subsequent myelination are essential for central nervous system development and regeneration. Deficiency in the extracellular factor laminin-2 (Lm2, comprising the α2β1γ1 chains), as occurs in congenital muscular dystrophy, can lead to impaired oligodendroglial development and aberrant myelination, but many aspects of Lm2-regulated oligodendroglial signaling and differentiation remain undefined. We show that receptor-like protein tyrosine phosphatase α (PTPα, also known as PTPRA) is essential for myelin basic protein expression and cell spreading during Lm2-induced oligodendrocyte differentiation. PTPα complexes with the Lm2 receptors α6β1 integrin and dystroglycan to transduce Fyn activation upon Lm2 engagement. In this way, PTPα mediates a subset of Lm2-induced signals required for differentiation, includeing mTOR-dependent Akt activation but not Erk1/2 activation. We identify N-myc downstream regulated gene-1 (NDRG1) as a PTPα-regulated molecule during oligodendrocyte differentiation, and distinguish Lm2 receptor-specific modes of Fyn–Akt-dependent and -independent NDRG1 phosphorylation. Altogether, this reveals an Lm2-regulated PTPα–Fyn–Akt signaling axis that is critical for key aspects of the gene expression and morphological changes that mark oligodendrocyte maturation.
Adaptive adhesion systems mediate glioma cell invasion in complex environments
Authors: Gritsenko Pavlo G. , Friedl Peter
Published: July 2018

Diffuse brain invasion by glioma cells prevents effective surgical or molecular-targeted therapy and underlies a detrimental outcome. Migrating glioma cells are guided by complex anatomical brain structures but the exact mechanisms remain poorly defined. To identify adhesion receptor systems and matrix structures supporting glioma cell invasion into brain-like environments we used 2D and 3D organotypic invasion assays in combination with antibody-, peptide- and RNA-based interference. Combined interference with β1 and αV integrins abolished the migration of U-251 and E-98 glioma cells on reconstituted basement membrane; however, invasion into primary brain slices or 3D astrocyte-based scaffolds and migration on astrocyte-deposited matrix was only partly inhibited. Any residual invasion was supported by vascular structures, as well as laminin 511, a central constituent of basement membrane of brain blood vessels. Multi-targeted interference against β1, αV and α6 integrins expressed by U-251 and E-98 cells proved insufficient to achieve complete migration arrest. These data suggest that mechanocoupling by integrins is relatively resistant to antibody- or peptide-based targeting, and cooperates with additional, as yet unidentified adhesion systems in mediating glioma cell invasion in complex brain stroma.
netSmooth: Network-smoothing based imputation for single cell RNA-seq
Authors: Ronen Jonathan , Akalin Altuna
Published: July 2018

Single cell RNA-seq (scRNA-seq) experiments suffer from a range of characteristic technical biases, such as dropouts (zero or near zero counts) and high variance. Current analysis methods rely on imputing missing values by various means of local averaging or regression, often amplifying biases inherent in the data. We present netSmooth, a network-diffusion based method that uses priors for the covariance structure of gene expression profiles on scRNA-seq experiments in order to smooth expression values. We demonstrate that netSmooth improves clustering results of scRNA-seq experiments from distinct cell populations, time-course experiments, and cancer genomics. We provide an R package for our method, available at: https://github.com/BIMSBbioinfo/netSmooth.
Identifying communities from multiplex biological networks by randomized optimization of modularity
Authors: Didier Gilles , Valdeolivas Alberto , Baudot Anaïs
Published: July 2018

The identification of communities, or modules, is a common operation in the analysis of large biological networks. The Disease Module Identification DREAM challenge established a framework to evaluate clustering approaches in a biomedical context, by testing the association of communities with GWAS-derived common trait and disease genes. We implemented here several extensions of the MolTi software that detects communities by optimizing multiplex (and monoplex) network modularity. In particular, MolTi now runs a randomized version of the Louvain algorithm, can consider edge and layer weights, and performs recursive clustering.

On simulated networks, the randomization procedure clearly improves the detection of communities. On the DREAM challenge benchmark, the results strongly depend on the selected GWAS dataset and enrichment p-value threshold. However, the randomization procedure, as well as the consideration of weighted edges and layers generally increases the number of trait and disease community detected.

The new version of MolTi and the scripts used for the DMI DREAM challenge are available at: https://github.com/gilles-didier/MolTi-DREAM.
A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities
Authors: Walther Frans J. , Gupta Monik , Gordon Larry M. , Waring Alan J.
Published: July 2018

Background: Animal-derived surfactants containing surfactant proteins B (SP-B) and C (SP-C) are used to treat respiratory distress syndrome (RDS) in preterm infants. SP-B (79 residues) plays a pivotal role in lung function and the design of synthetic lung surfactant. Super Mini-B (SMB), a 41-residue peptide based on the N- and C-domains of SP-B covalently joined with a turn and two disulfides, folds as an α-helix hairpin mimicking the properties of these domains in SP-B. Here, we studied ‘B-YL’, a 41-residue SMB variant that has its four cysteine and two methionine residues replaced by tyrosine and leucine, respectively, to test whether these hydrophobic substitutions produce a surface-active, α-helix hairpin.

Methods:Structure and function of B-YL and SMB in surfactant lipids were compared with CD and FTIR spectroscopy, and surface activity with captive bubble surfactometry and in lavaged, surfactant-deficient adult rabbits.

Results:CD and FTIR spectroscopy of B-YL in surfactant lipids showed secondary structures compatible with peptide folding as an α-helix hairpin, similar to SMB in lipids. B-YL in surfactant lipids demonstrated excellentin vitrosurface activity and good oxygenation and dynamic compliance in lavaged, surfactant-deficient adult rabbits, suggesting that the four tyrosine substitutions are an effective replacement for the disulfide-reinforced helix-turn of SMB. Here, the B-YL fold may be stabilized by a core of clustered tyrosines linking the N- and C-helices through non-covalent interactions involving aromatic rings.

Conclusions:‘Sulfur-free’ B-YL forms an amphipathic helix-hairpin in surfactant liposomes with high surface activity and is functionally similar to SMB and native SP-B. The removal of the cysteines makes B-YL more feasible to scale up production for clinical application. B-YL’s possible resistance against free oxygen radical damage to methionines by substitutions with leucine provides an extra edge over SMB in the treatment of respiratory failure in preterm infants with RDS.
APAC: institution for the resocialization of prisoners
Authors: Braga Luana Aparecida Barbosa , Vasconcelos Fernanda Carla Wasner , Ituassu Cristiana Trindade
Published: July 2018

The objective of this study was to analyze the method of resocialization practiced by APAC, Association for Protection and Assistance to the Prisoners stands out, an alternative to the treatment practiced in the prison system with lower cost than the common penitentiaries and superior results. In this case study, 17 semi-structured interviews were performed APAC-Itaúna (MG), in the year of 2016. The reports were submitted to the software IRAMUTEQ for the analysis of content according to Bardin and the results showed that APAC introjects its rules, standards and beliefs in the prisoners constituting an alternative model of detention management that is efficient, complying with the law of Penal Execution and not violating the human rights. The results of this study showed that the institution studied offers opportunities for resocialization of the prisoner through application of the structural elements of APAC method, which is discussed in the light of the administration.
Barganha do serviço público: estado da arte e agenda de pesquisa
Authors: Lima Luan Bernardo Lima Bernardo
Published: July 2018

A aliança ou o pacto entre Política e Administração é considerado essencial para o funcionamento das instituições públicas, compondo um tema clássico da Administração Pública e sendo objeto de estudos empíricos expressivos no âmbito internacional. Na academia brasileira, contudo, esta temática tem sido abordada de maneira esporádica sob o aspecto empírico. Diante deste cenário, este artigo apresentou a Barganha do Serviço Público, abordagem teórica que compreende a relação político-administrativa como uma troca entre recompensas econômicas e intangíveis dada aos servidores públicos em troca de certas competências e fidelidade pactuada com os políticos eleitos, e revisou a produção acadêmica que a utilizou por meio das bases de dados Scopus e Web of Sciences. Dessa forma, este artigo buscou situar esta abordagem como um suporte analítico relevante a fim de investigar a administração pública e o governo brasileiro, analisando os estudos selecionados mediante as características contextuais, metodológicas, teóricas e quanto aos resultados de pesquisa. Assim, por meio do estado da arte e das conclusões realizadas, foram desenvolvidas proposições para uma agenda de pesquisa no contexto brasileiro.
O processo de empresarização e as mudanças nas relações de assalariamento e exploração
Authors: Tometich Patricia , Silva Rosimeri De Fátima Carvalho
Published: July 2018

Neste ensaio questionamos o assalariamento como característica essencial de empresarização do mundo (SOLÉ, 2003; 2008; ABRAHAM, 2006), articulando a ideia de Mundo-Empresa (SOLÉ, 2008) com o ideario neoliberal, especialmente sua renovação (PUELLO-SOCARRÁS; 2008; 2013; LAVAL; DARDOT, 2013). Considerando que no ideário neoliberal o empreendedorismo é apontado como solução para geração de trabalho e renda, buscamos melhor compreender a expansão de empresa como o tipo hegemônico de organização. Apresentamos as modificações no mundo do trabalho e ilustramos nossa argumentação com a criação de duas categorías de empreendedores - independentes e dependentes, com inspiração no trabalho de Schumpeter (1982).  O resultado do estudo é que na teoría sobre o proceso de empresarização o assalariamento deve ser substituído pela relação de exploração do trabalho.
Força das relações: um survey em centros de beleza
Authors: Corrêa Rúbia Oliveira , Silva Luiz Marcos De Oliveira , Gomes de Carvalho Gustavo Dambiski , Sacramento Patrícia Melo
Published: July 2018

O presente estudo verificou a influência das características socioeconômicas e demográficas, assim como da duração, frequência e atributos do relacionamento, na força da relação desenvolvida entre clientes de centros de beleza em Foz do Iguaçu - PR. A pesquisa se caracteriza como descritiva e em sua abordagem classifica-se como quantitativa. A amostra é do tipo não probabilística por acessibilidade. Os dados foram coletados através de questionários e tratados por meio de frequências, teste qui-quadrado, análise fatorial e regressão logística binária. Os resultados apontam que há uma relação de dependência que revela uma influência direta das variáveis duração do relacionamento e atributos relacionais na força da relação empresa-cliente. A frequência de encontros e o gênero dos entrevistados, por sua vez, possuem uma relação associativa com a força da relação desenvolvida entre os clientes inquiridos e seus centros de beleza.
Optimal Design of Return Policies
Authors: Tran Thanh , Gurnani Haresh , Desiraju Ramarao
Published: July 2018

Quota-based and partial-refund return policies abound in practice between manufacturers and their resellers. While the literature has provided insights into the design of the partial-refund policy, little attention has been directed at the design of the quota-based return policy. Accordingly, this paper explores the relative preference of a quota-based policy vis-à-vis a partial-refund policy. We do this, first, in the context of risk-neutral channel partners to identify the strategic decisions of each party and the effect of demand uncertainty on the variation of their respective profits. Our results reveal that the manufacturer faces higher profit variation (between the different demand realizations) under the quota policy. The variance in profits for the reseller is, however, higher under the partial-refund policy. We explain the source of profit variations by comparing it across different channel structures (centralized and decentralized). Next, we formally extend the model to include a disutility associated with profit variation and show that when the manufacturer has a variation-induced disutility, the partial-refund contract should be used, as it is the dominating contract. Similarly, when the retailer has a variation-induced disutility, the quota contract should be used. This is consistent with the pattern of profit variations in the risk-neutral case where the manufacturer has lower variation with the partial-refund contract while the reseller has lower variation with the quota contract. Finally, our analysis also shows how the manufacturer may employ a combination policy to better manage its own profit variation while providing adequate overstocking protection for the reseller.

The online appendix is available at https://doi.org/10.1287/mksc.2018.1094 .
The Term Structures of Coentropy in International Financial Markets
Authors: Chabi-Yo Fousseni , Colacito Riccardo
Published: July 2018

We propose a new entropy-based correlation measure (coentropy) to evaluate the performance of international asset pricing models. Coentropy captures the codependence of two random variables beyond normality. We document that the coentropy of international stochastic discount factors (SDFs) can be decomposed into a series of entropy-based correlations of permanent and transitory components of the SDFs. We employ the cross section of G-10 countries to obtain model-free estimates of all the components of coentropy at various horizons and we show that the generalization of the long-run risk model featuring two predictable components of consumption growth rates, global disasters, and recursive preferences can account for the composition of codependence at all horizons.

This paper was accepted by Tomasz Piskorski, finance.
The Implications of Visibility on the Use of Strategic Inventory in a Supply Chain
Authors: Roy Abhishek , Gilbert Stephen M. , Lai Guoming
Published: July 2018

It is now widely accepted that a retailer’s use of strategic inventory can mitigate double marginalization and improve the coordination of a supply chain, potentially benefiting both the downstream retailer and an upstream manufacturer. However, this conclusion has typically been based on the assumption that the manufacturer can observe the retailer’s level of inventory before making wholesale pricing decisions. In reality, there are many situations in which neither the retailer’s sales nor inventory are observable to the manufacturer, effectively concealing the action taken by the retailer. We investigate the implications of such a lack of observability on the use of strategic inventory in a supply chain consisting of a single retailer and a single manufacturer. We find that the manufacturer’s inability to observe inventory has significant implications for the amount of inventory and the range of holding cost for which it is held in equilibrium. In addition, we find that, in the absence of any form of uncertainty, which the manufacturer could benefit from responding to, he may prefer not to observe the retailer’s inventory. On the other hand, the retailer’s willingness to make her inventory visible depends on the holding cost.

The electronic companion is available at https://doi.org/10.1287/mnsc.2018.3033 .

This paper was accepted by Gad Allon, operations management.
Solidão: do patológico ao ontológico
Authors: Macedocouto Graco Silva , Silva Junior Almir Ferreira da
Published: July 2018

O objetivo do presente artigo é problematizar o fenômeno da solidão enquanto experiência significativa, no horizonte de nossas relações sociais e afetivas, considerando a legitimidade de sua significação patológica, bem como a primazia de sua ressignificação ontológica. Destaca-se o caráter ontológico da solidão em oposição ao seu horizonte hermenêutico técnico-científico e biomédico destacando os limites desta abordagem, no tocante à compreensão existencial do fenômeno da solidão. Explicita-se a dimensão ontológica da solidão a partir da fenomenologia de Heidegger ressaltando os fundamentos de uma analítica existencial e a reflexão da solidão enquanto tonalidade afetiva que constituem o ser humano enquanto ser-no-mundo e com-os-outros. Problematiza-se a insuficiência da concepção patológica da solidão para compreendê-la enquanto experiência existencial originária e que se estabelece no horizonte de nossa temporalidade, a partir dos existenciais do ser-com e da tonalidade afetiva da angústia. Ressalta-se a proximidade entre a angústia e a solidão enquanto isolamento existencial, e a importância de se estabelecer junto à angústia e à solidão o que Heidegger denomina de pensamento meditante para a abertura de novos sentidos que permitam o resgate da responsabilização de nossos projetos existenciais, nossa singularização e liberdade.
A experiência de mundo de uma surda ao aprender LIBRAS: uma abordagem fenomenológico-existencial
Authors: Thomaz Amanda Galerani , Freitas Joanneliese De Lucas
Published: July 2018

Frequentemente os diferentes discursos sobre a experiência da surdez partem da perspectiva dos ouvintes, tornando opaca essa vivência tão particular. Esse trabalho pretendeu se aproximar da experiência de se viver no mundo cultural sem a apropriação de uma língua sistematizada. Para tanto, foi realizado um estudo de caso sobre uma surda que aprendeu a Língua Brasileira de Sinais (LIBRAS) já adulta. A coleta de dados deu-se por meio de uma entrevista aberta, mediada por um intérprete voluntário de LIBRAS. A análise da entrevista foi orientada pelo método fenomenológico de investigação de Giorgi e os dados interpretados a partir da perspectiva de Merleau-Ponty. Os resultados foram divididos em dois grupos temáticos: O mundo sem sentido: vazio e solidão e O despertar aos sentidos: "uma nova vida". As vivências anteriores ao domínio de uma língua sistematizada foram descritas como incompreensíveis e vazias, permeadas por dissociações e experiências esparsas. Ao aprender LIBRAS, a entrevistada relata uma mudança brusca na forma como se relacionava com o mundo, começando a perceber sentidos e gestos compartilhados culturalmente. Sugere-se estudos mais aprofundados que investiguem o sensível e a corporeidade na experiência das pessoas surdas. Destaca-se a importância da apropriação da língua sistematizada.
Eu sou o que me dizem que sou? Zombaria, Habilidades Sociais e Autoconceito
Authors: Benatti Lívia Andrade , Souza Débora De Hollanda
Published: July 2018

O presente estudo teve como objetivo principal investigar se as habilidades sociais poderiam funcionar como uma variável moderadora na relação entre a provocação dos colegas e o autoconceito. Quarenta e oito meninas entre 9 e 10 anos foram avaliadas por uma escala de autoconceito (EAC-IJ), por um componente do instrumento de avaliação de habilidades sociais (SMHSC-Del Prette), baseado em autorrelato, e responderam a um questionário que fornecia uma medida da frequência de provocação/zombaria feita por colegas. Além disso, as professoras das participantes fizeram uma avaliação do nível de socialização das participantes, utilizando uma escala de 10 pontos, criada pelas pesquisadoras. Os resultados revelaram uma tendência para um efeito moderador do nível de socialização na relação entre provocação e autoconceito. As participantes que foram consideradas mais sociáveis pareciam sofrer menos os efeitos negativos da provocação e, consequentemente, apresentaram escores maiores na escala de autoconceito do que as participantes consideradas menos sociáveis.
Revisão bibliométrica da produção brasileira sobre turnover no período de 1980 a 2015
Authors: Beria Francielle Machado , Ligorio Isadora , Pinhatti Marcelle Matiazo , Boucinha Daniela , Oliveira Manoela Ziebell de
Published: July 2018

Rotatividade, ou turnover no mercado de trabalho, diz respeito à saída permanente de profissionais de seus postos e à admissão de novos profissionais pelas organizações. Devido à mudança de estilos de carreiras tradicionais para contemporâneas, houve um crescimento exponencial na rotatividade dos profissionais dentre as organizações. Apesar desta realidade, nota-se um número pequeno de estudos brasileiros sobre o tema. O objetivo do presente artigo foi caracterizar a produção nacional e discutir as potencialidades e limitações dos estudos desenvolvidos no contexto brasileiro para o entendimento e a gestão da rotatividade de profissionais em organizações de trabalho. O método consiste em uma revisão da literatura brasileira sobre rotatividade de pessoal produzida entre 1980 e 2015, e divulgada no Portal de Periódicos da CAPES e na base de dados Scielo. Foram identificados 59 artigos. Os resultados mostraram que, apesar do impacto econômico da rotatividade para organizações, indivíduos e sociedade, a produção nacional sobre o tema além de permanecer escassa, encontra-se dispersa em diferentes centros do país. Verifica-se a necessidade de desenvolver instrumentos nacionais que viabilizem a pesquisa sobre rotatividade, bem como de ampliar os contextos de investigação sobre o tema, envolvendo diferentes tipos de organização e métodos de coleta e análise de dados.
Deus está morto. Viva o autômato!
Authors: Weinmann Amadeu De Oliveira , Medeiros Roberto Henrique Amorim de , Mano Gustavo Caetano de Mattos
Published: July 2018

O artigo propõe-se a pensar algo do pathos da Modernidade – a paixão pelo autômato –, à luz do conceito nietzschiano Morte de Deus. Nesse sentido, toma como matéria de análise dois clássicos do cinema de ficção científica: 2001: uma odisseia no espaço, de Stanley Kubrick, e Blade runner, de Ridley Scott. Se a paixão pelo autômato consiste em uma forma do sujeito moderno denegar a finitude, nos filmes em debate tal condição é elaborada de um modo muito singular. 2001 e Blade runner oferecem ao espectador a possibilidade de resistir à assunção dessa inclinação da subjetividade moderna. Em 2001, o autômato é demasiado humano e uma narrativa trágica promove outro modo de enfrentar a finitude. Em Blade runner, o autômato é o portador das angústias fundamentais do sujeito moderno – origem e finitude – e a identificação a ele permite ao espectador ir além do homem.
Dealing with emotional events on placement
Authors: Chapman Eleanor
Published: July 2018

In this column, 3rd year student Eleanor Chapman reveals the emotional difficulties that can be found on placement, and the truth that sometimes the necessary support isn't there. She discusses the importance of reflection and of having an outlet where experiences can be shared openly
Options for replacing missing teeth during orthodontic treatment
Authors: O'Rourke Niamh , Taylor Nigel
Published: July 2018

Abstract: Patients presenting for orthodontic treatment with missing teeth in the anterior region have an added concern about how aesthetics will be affected over the duration of treatment. It is important to maintain the best possible aesthetics during treatment as this may affect patient confidence, motivation and enthusiasm. This paper reviews the techniques used to maintain aesthetics during orthodontic treatment for patients who require eventual replacement of a missing tooth. The advantages and disadvantages of the different treatment options are discussed.

CPD/Clinical Relevance: To understand the treatment options for temporary replacement of missing teeth during orthodontic treatment.
Genetic engineering of sweet potatoes (Ipomoea batatas) using isopentenyl transferase gene for enhanced drought tolerance
Authors: NAWIRI SYLVIA OBINDA , ODUOR RICHARD OKOTH , JALEMBA ALLAN MGUTU
Published: July 2018

Abstract. Nawiri SO, Oduor RO, Jalemba AM. 2017. Genetic engineering of sweet potatoes (Ipomoea batatas) using isopentenyl transferase gene for enhanced drought tolerance. Asian J Agric 1: 85-99. Approximately 70% of yield crop reduction worldwide is caused by drought. Due to severe drought, which happens often as a result of climate change, substantial yield deprivation is usual among the major cereals such as maize, wheat, and barley. Therefore, drought tolerant crops that still yield amidst erratic climatic phenomena are greatly needed. Due to its capability to produce high yield in a short period, sweet potato is suitable for cultivation in regions with limited or erratic rainwater supply where other food crops cannot grow easily. Nevertheless, its sensitivity to water deficit may lead to adverse crop growth and yield. By conventional hybridization method, sweet potato is tried to be improved, but it gives unsatisfied results due to its high male sterility, sexual incompatibility and hexaploidy nature of its genome. The aim of this study, therefore, is to develop new varieties of sweet potato with improved tolerance to water-deficit stress for sustainable production of sweet potato under water-limited conditions. Three sweet potato genotypes: Jewel, Kemb36, and Ksp36 were transformed using isopentenyl transferase gene (IPT) that delays drought-induced senescence via up-regulation of cytokinin biosynthesis, under the control of a water-deficit responsive and maturation specific promoter (PSARK). The PNOV-IPT gene construct was introduced into sweet potatoes to evaluate their transformability and regenerability. It was done via Agrobacterium tumefaciens strain EHA101 and the plants subsequently regenerated via somatic embryogenesis. Jewel genotype recorded the highest transformation and regeneration frequency, followed by Kemb36 and KSP36. Calli were cultured on media supplemented with various mannose concentrations to evaluate the suitability of mannose as a selectable marker for sweet potato, and it was discovered that 30 g/L concentration was optimal for selection of transformed events. At the time of PCR analysis, Jewel had the highest transformation efficiency followed by Kemb36. At the time for evaluation on drought tolerance under controlled conditions, the sweet potato showed delayed senescence and greater drought tolerance under water deficit conditions in the glasshouse. These plants exhibited better growth, higher yield, higher water status maintenance, higher chlorophyll content, and thus higher photosynthetic rates under reduced water conditions in comparison to wild-type. These results, therefore, indicated that expression of isopentenyl transferase gene in sweet potato significantly improves drought tolerance. Therefore, IPT gene should be used to transform other economically important food crops to delay drought-induced senescence and enhance drought tolerance.
Seed emergence and growth of the shortage sugar palm (Arenga pinnata) as a response to seed scarification and liquid organic fertilizer application
Authors: ELIDAR YETTI
Published: July 2018

Abstract. Elidar Y. 2018. Seed emergence and growth of the shortage sugar palm (Arenga pinnata) as a response of seed scarification and liquid organic fertilizer application. Asian J Agric 2: 8-13. This research aimed to know the effect of seed scarification and liquid organic fertilizer application on the seed emergence and growth of the shortage sugar palm (Arenga pinnata (Wurmb.) Merr). The research was conducted in two experiments, i.e. (i) effect of seed scarification, and (ii) effect of liquid organic fertilizer application. The first experiment was a single factor designed at Completely Randomized Design (CRD). The factor consisted of 4 scarification technique treatments i.e., s1 = seed abaxial scarification; s1 = seed tip scarification; s3 = seed left and right sides scarification; s4= seed embryo scarification. All treatments were replicated 6 times. The second experiment was arranged at a factorial (3 x 3) using Completely Randomized Design (CRD) with 6 replications. The first factor was the dose/volume of liquid organic fertilizer treatment in concentration of 3 cc L-1 of water (D) consisting of 3 levels i.e., d1 = 300 mL; d2 = 400 mL; d3 = 500 mL, while the second treatment was the interval of liquid organic fertilizer (I) application consisting of 3 levels i.e., i1 = 2 weeks; i2 = 3 weeks; i3 = 4 weeks. Seedling emergence test, germination rate, vigor index and seed germination percentage were measured and the growth parameters such as the plant height increase, plant midrib girth, number of midrib increase, and number of leaves were observed. The results showed that scarification at the embryo part (s4) resulted in the best seed germination percentage of the shortage sugar palm at around 99.81%. Combination treatments between 500 mL dose of liquid organic fertilizer in concentration of 3 cc L-1 of water with the interval of 2 weeks (d3i1) produced the best seedling growth of the shortage sugar palm.
Biomass production of Azolla microphylla as biofilter in a recirculating aquaculture system
Authors: SUMOHARJO SUMOHARJO , MA’RUF MOHAMMAD , BUDIARTO IRWAN
Published: July 2018

Abstract. Sumoharjo, Ma’ruf M, Budiarto I. 2018.Biomass production of Azolla microphylla as biofilter in a recirculating aquaculture system. Asian J Agric 2: 14-19. This study utilized macrophyte (Azolla microphylla Kaulf.) as a biofilter and investigated that biomass produced in an aquaculture system could potentially be an alternative feed. This experiment was aimed to determine the Azolla microphylla growth rate and its efficiency in removing ammonia from a simple recirculating aquaculture system. The experimental units were set up in three different water flows, i.e. 3 lpm, 5 lpm, and 7 lpm onto the three different geometrically baseboards of Tilapia (Oreochromis niloticus) growing tanks (prism, rectangular and limas). The results showed that water flow did not give significant effect(P < 0.10) on the growth rate of Azolla. The lower water flow (3 lpm) resulted in the highest ammonia biofiltration efficiency, which can remove ammonia up to 32.2±3.0% of the total NH3-N and NH4+-N (TAN).
Short Communication: The potential of Sulfate Reducing Bacteria of ex-coal mine sediment pond as sulfate reducing agents of acid land in Samarinda, Indonesia
Authors: KUSUMAWATI EKO , SUDRAJAT SUDRAJAT , PURNAMASARI IKA , PANGGABEAN BINA CRISTYANTI , APRIYANTI MAIDA
Published: July 2018

Kusumawati E, Sudrajat, Purnamasari I, Panggabean BC, Apriyanti M. 2017. Short Communication: The potential of Sulfate Reducing Bacteria of ex-coal mine sediment pond as sulfate reducing agents of acid land in Samarinda, Indonesia. Bonorowo Wetlands 1: 79-82. The study aims to determine the effect of pH medium on the growth of sulfate reducing bacteria taken from the e-coal mine sediment pond and to determine its potential as a reducing sulphate agent of acid ex-coal mine land in Samarinda, East Kalimantan, Indonesia. Six SRB isolated from ex-coal mine sediment pond in Samarinda were used in this study. The SRB potency test in reducing sulfate was conducted by growing the SRB on Postgate liquid medium at different pH of 2, 4 and 6 by the addition of acid soils on each treatment. The results showed that sulfate reducing bacteria isolated from ex-coal mine sediment pond in Samarinda,, i.e., sp.1 (Desulfococcus sp.), sp.2 (Desulfotomaculum sp.), sp.3 (Desulfobacter sp.), sp.4 (Desulfobulbus sp. ), sp.5 (Desulfobacterium sp.) and sp.6 (Desulfotomaculum sp.) had potential as sulfate reducing agent of acid land. The efficiency of sulfate reduction was 89%, 91% and 91% in the pH of 2, 4 and 6, respectively. This indicated that the highest number of sulfate reduction is in the medium with pH 4 and pH 6. In addition, sp.5 (Desulfobacterium sp.) growing on medium at pH 4 had the best sulfate reduction efficiency (93%) compared with other SRB isolates.
Elite capture of local participatory governance
Authors: Waheduzzaman Wahed , As-Saber Sharif , Hamid Mohotaj Binte
Published: July 2018

Elite capture is a major barrier to citizen engagement in local governance processes in many developing countries. Data from six case studies of development initiatives in Bangladesh show that, in spite of attempts by aid donors and others to ensure citizen participation, programmes are dominated by a nexus of local elites including MPs and bureaucrats. Local stakeholders do not understand the value that direct citizen participation can bring, and citizens are unaware of their rights and wary of challenging elites. Monitoring of requirements for citizen participation is weak, and the management of some programmes deters participation. Representatives are sometimes selected by elites and legal frameworks are not sufficiently strong or enforced consistently. We conclude that a range of additional and effectively implemented policy measures are required to reduce the extent and effects of elite capture in developing countries.
Theorising feminist organising in and against neoliberalism: beyond co-optation and resistance?
Authors: Eschle Catherine , Maiguashca Bice
Published: July 2018

This article reviews contemporary academic debates about feminist organising in and against neoliberalism, which we see as structured by a co-optation–resistance dichotomy. We outline three narratives: a high-profile ‘strong’ co-optation thesis; a more nuanced co-optation discourse; and an emergent counter-narrative of resistance. While sympathetic to the latter two, we critically unpack the account of neoliberalism, of feminist protagonists and of where feminist activism takes place in all three. We sketch out ways in which neoliberalism and the ‘who’ and ‘where’ of feminism might be considered differently, and argue overall for the need to move beyond the co-optation–resistance dichotomy.
With or without feminism? Researching gender and politics in the 21st century
Authors: Ackerly Brooke , True Jacqui
Published: July 2018

Studying politics and gender without feminism is akin to institutionalising democracy without women. We argue that it is not possible to understand the gender dynamics of politics without feminism. We show the benefits of doing ‘Politics and Gender’ with feminist analysis and of analysing gender and doing feminism grounded in the study of politics. The article is organised around a series of critical questions that researchers investigating the relationship between politics and gender should ask to improve both the rigour and the transformative impact of their research. Our answers illustrate the essential role of feminism to gendered inquiry.
Central American cinematographic aesthetics and their role in international film festivals
Authors: Cabezas Vargas Andrea , González de Canales Carcereny Júlia
Published: July 2018

This article provides a brief aesthetic history of Central American cinema, outlining the impact of limited resources, sociopolitical conflicts and global aesthetic trends on regional film production. Focusing on films produced in the late 1990s and the early 2000s, it analyses how contemporary Central American films have overcome economic and material limitations and generated films that obtained acclaim in regional and international circuits. It also analyses the impact of international film festivals on Central American film production, focusing on the work of the Central American, yet also transnational, directors Julio Hernández Cordón and Tatiana Huezo.
Symptoms of a civil war: Affect, disease and urban violence in Arturo Menéndez’s Malacrianza/The Crow’s Nest (2014)
Authors: Caña Jiménez María del Carmen
Published: July 2018

Arturo Menéndez’s award-winning Malacrianza/The Crow’s Nest (2014) chronicles the tribulations of Don Cleo, a poor piñata salesman suffering from mental and physical ailments. Cleo’s life is turned upside down when he receives an extortion letter asking for US$500 in exchange for his life. This article examines Malacrianza’s linkage between the protagonist’s body and his ailments and the broader sociopolitical matrix. I argue that the symptoms he demonstrates are manifestations of the impact of civil war and urban violence upon the social telos of Central America. My study explores phenomenological film analysis as a tool for examining affects and their circulations in the film. By using an affective code, Malacrianza engages the viewer in an intimate experience of the violence(s) of contemporary El Salvador.