bluuebunny/crossref_metadata_2025 huggingface dataset:
Cannabinoid hyperemesis syndrome complicated by pneumomediastinum: implications for pediatrics
Authors:   UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM, DIVISION OF PEDIATRIC SURGERY, DEPARTMENT OF SURGERY, CHICAGO, IL, USA, Klazura Greg , Geraghty Joseph ,   UNIVERSITY OF ILLINOIS AT CHICAGO COLLEGE OF MEDICINE, MEDICAL SCIENTIST TRAINING PROGRAM, CHICAGO, IL, USA, Rojnica Marko ,   UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM, DIVISION OF PEDIATRIC SURGERY, DEPARTMENT OF SURGERY, CHICAGO, IL, USA, Sims Thomas ,   UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM, DIVISION OF PEDIATRIC SURGERY, DEPARTMENT OF SURGERY, CHICAGO, IL, USA, Koo Nathaniel ,   UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM, DIVISION OF PEDIATRIC SURGERY, DEPARTMENT OF SURGERY, CHICAGO, IL, USA, Lobe Thom ,   UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM, DIVISION OF PEDIATRIC SURGERY, DEPARTMENT OF SURGERY, CHICAGO, IL, USA
Published: December 2022

Background. Cannabinoid hyperemesis syndrome / CHS (prolonged and frequent use of high-dose cannabis) in the pediatric population has been increasingly reported over the last decade. CHS can lead to life-threatening complications such as pneumomediastinum, which warrant careful consideration for surgical intervention. Case Presentation. A 17-year-old female with no significant past medical history presented to the emergency department with abdominal, chest and back pain (worse with deep inspiration), nausea, and vomiting for 24 hours. Upon further history, the patient reported a similar episode six months ago, being a cannabis smoker (at least once a day) in the last two years. Chest X-ray revealed a subtle abnormal lucency along the anteroposterior window and anterior mediastinum, consistent with a small amount of pneumomediastinum without any other acute intrathoracic abnormalities. Follow-up chest computed tomography with contrast showed multiple foci of air within the anterior and posterior mediastinum tracking up to the thoracic inlet. There was no evidence of contrast extravasation; however, small esophageal perforation could not be excluded. Given uncomplicated pneumomediastinum (without frank contrast extravasation) the patient was treated medically with piperacillin-tazobactam, metronidazole, and micafungin for microbial prophylaxis; hydromorphone for pain control; as well as with pantoprazole, ondansetron, and promethazine. Nutrition was provided via total parenteral nutrition. The evolution was favorable (no signs of occult esophageal perforation occurred), being advanced to a soft diet on hospital day eight, solid food diet on day nine, at which point antibiotics were discontinued, and the patient was subsequently discharged. Conclusion. CHS in increasingly encountered in the pediatric setting due to rising prevalence of cannabis use. The management of CHS and potentially life-threatening complications such as pneumomediastinum should be given careful consideration. Pneumomediastinum can be a harbinger of esophageal perforation that may warrant urgent surgical intervention.
A rare cause of abdominal pain: Acute pancreatitis due to intragastric balloon
Authors:   AĞRI İBRAHIM ÇEÇEN UNIVERSITY FACULTY OF MEDICINE DEPARTMENT OF GENERAL SURGERY, AĞRI, TURKEY, Kalayci Tolga , Tayar Serkan ,   DEPARTMENT OF GENERAL SURGERY, MEDICAL PARK TRABZON KARADENIZ HOSPITAL, TRABZON, TURKEY
Published: December 2022

The intragastric balloon is one of the interventional treatments used to treat obesity. This case report presents a 28-year-old woman undergoing intragastric balloon insertion to treat obesity. Thirty-five days later, she was admitted to the emergency department with acute abdominal pain, nausea, and vomiting. During the physical examination, she had pain on deep palpation in the right lower quadrant. The laboratory showed only high serum amylase levels of 563 IU/L (range 28-100 IU/L). The abdominal ultrasound did not detect gallstones or enlarged intra or extrahepatic ducts. A computed tomography scan was performed, and intragastric balloon and distal pancreatic oedema without mass and peri-pancreatic fluid collection were detected. Intravenous hydration and anti-biotherapy were started. On the second day of hospitalization, the patient's amylase value returned to the normal range (40 IU/L). The patient who tolerated oral intake was discharged on the 3rd day of hospitalization. Diagnosis of pancreatitis is made by a history of intragastric balloon insertion, a pancreatitis-like clinical picture, and biochemical and radiological confirmation of the clinical diagnosis. In such cases, conservative therapy should be applied first; the intragastric balloon should be removed only in patients resistant to treatment or with a long-term intragastric balloon.
Rectal GIST mimicking an ovarian mass; a case report
Authors:   SALAH AZAIEZ INSTITUTE, DEPARTMENT OF SURGICAL ONCOLOGY, TUNIS, TUNISIA, Oumeima Khaldi , Montassar Ghalleb , Slim Rajhi , Maher Slimane , Raoudha Doghri , Ghada Sahraoui , Riadh Chargui , Rahal Khaled
Published: December 2022

Introduction. Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal neoplasms of the gastrointestinal (GI) tract. However, rectal GISTs are rare among these tumors. Case Presentation. A 60-year-old Caucasian woman had surgery for an ovarian mass with carcinomatosis. The patient underwent exploratory laparoscopy, which found a large amount of ascites, epiploic and appendicular carcinomatosis. The Hudson operation was performed to completely and en bloc remove the recto-sigmoid junction, the uterus, and adnexa. The appendix and the carcinomatosis were also removed with no residual tumor. After that, she was sent to the oncology department to start Imatinib therapy. Conclusion. Rectal GIST is a rare entity with varied clinical manifestations and a high risk of recurrence, which may complicate the diagnosis in women with an abdominopelvic tumor mass. Consequently, even if GIST can mimic gynecological tumors, such as ovarian tumor, the surgeon must be aware of this condition and take it into account in establishing the differential diagnosis, especially since surgical treatment is essential in localized rectal GIST.
Hyperbilirubinemia as a diagnostic marker in gangrene or perforation of acute appendicitis
Authors:   MBBS, MS(GENERAL SURGERY), ASSISTANT INSURANCE MEDICAL OFFICER, EMPLOYMENT STATE INSURANCE DISPENSARY, KERALAPURAM, Shaheed S , Ramlal R V. , AneeshRaj A , Vinod P. B.
Published: December 2022

Background. Although several scoring systems are available for the diagnosis of acute appendicitis, there is no one specific for the diagnosis of gangrenous or perforated appendicitis. This study aims to evaluate the sensitivity and specificity of serum total bilirubin in gangrene or perforated appendicitis. Materials and Methods. A prospective study was conducted on 55 patients undergoing emergency appendectomy, in whom total serum bilirubin was determined for statistical analysis. Results. In our study, out of 55 patients with a perforated or non-perforated appendix, the mean total serum total bilirubin was 2.34 and 1.27, respectively. The cut-off value of serum total bilirubin in this study was calculated using the ROC curve and found to be 1.75. Hyperbilirubinemia is 92.7% sensitive and 96.4% specific in perforation or gangrene of acute appendicitis. The positive predictive value was 96.2% and the negative predictive value was 93%. Conclusions. Patients with acute appendicitis and increased bilirubin levels have a higher chance of gangrene or perforation than those with normal bilirubin levels. Estimation of total serum bilirubin is available in most centers at minimal cost, and can therefore be used in conjunction with clinical and laboratory investigations for the diagnosis of gangrenous or perforated appendicitis.
Investigation of clinical efficacy and safety of a new herbal “Algan Hemostatic AgentTM” in lumbar disc herniation operations
Authors:   KARTAL DR. LÜTFI KIRDAR CITY TRAINING AND RESEARCH HOSPITAL, DEPARTMENT OF NEUROSURGERY, ISTANBUL, TURKEY, Tiryaki Mehmet , Çakaloğlu Haluk , Tatarlı Necati , Dayıoğlu Nurten
Published: December 2022

Aim. ALGAN Hemostatic Agent (AHA) is obtained with a standard mixture of 6 different herbs. It is a polysaccharide based hemostatic agent. The purpose of this study is to determine the clinical efficacy and reliability of AHA as a local hemostatic agent in lumbar disc herniation operations. Materials and Methods. In the study, the hemostatic efficacy of the product was observed on 28 volunteers underwent lumbar disc herniation surgery. In the treatment and control groups (14 patients each), operation times, bleeding stop times, pre- and postoperative hematocrit values (amount of blood loss), duration of hospital stay, and need for cautery use were compared. Traditional methods (cautery, ligation, etc.), which are used as a hemostatic in the operation, were always ready to be used effectively. The AHA application took 120 seconds. Results. While there was no difference between the groups in terms of preoperative hemoglobin and hematocrit values, postoperative hemoglobin and hematocrit values were statistically significant (p=0.033, 0.043). The amount of cautery use decreased significantly in the treatment group and the result was found to be statistically significant (p=.0.001). There was no significant difference in blood transfusion and mean operation times. Conclusions. AHA has been shown to be both effective in controlling bleeding and safe, so it can be used as an auxiliary product in capillary bleeding control in lumbar disc operations.
Is the long head of the biceps related to anterior shoulder pain? A histopathological study
Authors:   ISKENDERUN GELISIM HOSPITAL, DEPARTMENT OF ORTHOPEDICS AND TRAUMATOLOGY, ISKENDERUN, TURKEY, Pehlivan Ali , Keskin Ahmet , Yuce Ali , Guler Yasin , Karslioglu Bulent , Dedeoglu Suleyman
Published: December 2022

Objectives. Pathologies of the long head of the biceps have been viewed as a source of anterior shoulder pain and disability. Thus, we performed a histopathological and immunohistochemical examination of the biceps tendon with regard to the neuronal structure, the number of mechano[1]receptors and immunohistochemical types, to investigate the relationship of these factors with pain. Materials and Methods. This is a single-center prospective comparative study, on 11 patients divided into Group A (n=5) and Group B (n=6). Patients who underwent arthroplasty due to Neer type[1]4 proximal humeral fractures were selected as the control group (Group A). Group B consisted of patients with chronic anterior shoulder pain who underwent subpectoral biceps tenodesis during arthroscopic rotator cuff repair. The long head of biceps tenodesis was performed in all patients. Results. Hyalinization in the tendon was observed in 2 patients of group B. Chondroid degeneration was found in one patient with hyalinization. Inflammation, calcification, or matrix formation were not detected in any patients. Normal nerve fibers were observed around the tendon in 9 patients with S-100 immunohistochemical staining. In 1 patient, weak staining was observed in the nerve sheath with EMA immunohistochemical stain. No tactile body was detected. Conclusions. We did not observe any histo[1]pathological findings that could be considered the cause of pain in the two groups. Biomolecular and biomechanical studies, in addition to microscopic studies, are needed to explain why the biceps is a potential source of pain.
Comparison of patient outcomes with and without graft following modified high tibial osteotomy
Authors:   PROF. DR. CEMIL TASCIOGLU CITY HOSPITAL, DEPARTMENT OF ORTHOPAEDICS AND TRAUMATOLOGY, SISLI, ISTANBUL, TURKEY, Tasatan Ersin , Tekın Esra
Published: December 2022

Objectives. The aim of this study is to evaluate the early results of patients with and without grafting with the proximal tibia medial biplanar open wedge osteotomy technique used in the surgical treatment of varus gonarthrosis and to compare them with the literature. Materials and Methods. Thirty-six patients with medial gonarthrosis with varus alignment were included in the study. The proximal tibia medial biplanar open wedge osteotomy was performed on thirtysix knees. In eighteen of these patients, a tricortical graft was applied to the osteotomy site from the iliac wing being noted as Group 1. The other patients who did not receive grafts constituted Group 2. All patients were evaluated according to the Ahlbäck classification. Leg length radiographs were taken for all patients, and the osteotomy angle was calculated according to Paley's measurements. Results. Although the mean union-time at the osteotomy site was shorter in the Group 1, it was not statistically significant. No significant difference was observed in terms of HSS scores, and no reduction loss was observed in any patient. The hematoma was seen in three patients in Group 2 and one patient in Group 1. The donor site problems were observed in 10 patients in Group 1. Conclusions. With proximal tibia medial biplanar osteotomy, frontal plane and sagittal plane deformities can be corrected in patients with varus gonarthrosis, and good clinical results can be obtained without using grafts, thus avoiding donor site complications.
Primeros registros de dos especies y dos géneros de hormigas (Hymenoptera: Formicidae) colectadas en una zona semiurbana de Yucatán, México
Authors: Cano-Ravell Alan , Rosas-Mejía Madai , Vásquez-Bolaños Miguel , Ballina-Gómez Horacio Salomón , Tuyin-Díaz Ana Luz , Reyes-Solís Guadalupe del Carmen
Published: December 2022

Se reportan los primeros registros de dos especies de hormigas, i.e., Hypoponera opacior y Pseudomyrmex seminole y dos géneros, i.e., Acanthosticus y Mycetosoritis (Hymenoptera: Formicidae), asociados a etapas de descomposición de necrotrampas colocadas en una zona semiurbana del estado de Yucatán, México.
A AUTONOMIA PRIVADA NA CESSÃO DE DIREITOS HEREDITÁRIOS E O DIREITO DE PREFERÊNCIA
Authors: Zanini Leonardo Estevam de Assis , Queiroz Odete Novais Carneiro
Published: December 2022

O presente artigo analisa o regime jurídico da cessão de direitos hereditários, assunto de grande relevância prática no direito brasileiro. A matéria não era diretamente prevista pelo Código Civil de 1916, o que gerava divergências entre os estudiosos. Trata-se de pesquisa que utiliza metodologia descritiva e dedutiva, baseada fundamentalmente na investigação bibliográfica, jurisprudencial e legislativa. Para tanto, o texto estuda, em um primeiro momento, a indivisibilidade da herança e a responsabilidade dos herdeiros pelas dívidas hereditárias. Em seguida, passa-se ao exame do conceito, do objeto, dos requisitos, das condições e dos limites da cessão de direitos hereditários no Código Civil de 2002. Por fim, analisa-se o direito de preferência dos coerdeiros, que também passou a ser expressamente reconhecido pela legislação brasileira.
O PRINCÍPIO DA SUBSIDIARIEDADE, O BENEFÍCIO ASSISTENCIAL DE PRESTAÇÃO CONTINUADA E A SÚMULA Nº 23 DA TURMA REGIONAL DE UNIFORMIZAÇÃO DOS JUIZADOS ESPECIAIS FEDERAIS DA 3ª REGIÃO
Authors: Zacharias Rodrigo , Azevedo Paulo Bueno de , Haik Cristiane
Published: December 2022

Contextualização: Segundo a súmula nº 23 da Turma Regional de Uniformização do Juizado Especial Federal da 3ª Região, a concessão do benefício assistencial de prestação continuada (BPC), previsto no art. 203, V, da Constituição, devido a idosos com mais de 65 anos e pessoas com deficiência, dependerá da análise da obrigação alimentar de parentes, nos termos positivados no Código Civil, de modo que somente será concedido o benefício em caráter subsidiário à capacidade de sustento do núcleo familiar do requerente. Objetivo: O objetivo deste estudo é aferir se o entendimento contido na referida súmula é consonante com os objetivos magnos da Constituição Federal “dirigente” de 1988, contidos em seu art. 3º, bem assim se é compatível com as regras do art. 20 e §§ da Lei n.º 8.742/91 (Lei Orgânica da Assistência Social). Método: O presente estudo utiliza métodos dedutivo e indutivo, mediante pesquisas bibliográfica, legislativa e jurisprudencial. Resultados. Analisam-se o significado do princípio da subsidiariedade, a Doutrina Social da Igreja e a obrigação alimentar prevista no Código Civil e no art. 229 da Constituição Federal. Concluiu-se que a súmula nº 23 da TRU da 3ª Região, expressiva do princípio da subsidiariedade, atende aos fins sociais mas deve ser aplicada com cautela pelo juiz na apreciação da miserabilidade no caso concreto. Contribuições. O artigo apresenta uma noção precisa da subsidiariedade, contextualizando-a com as realidades trazidas a julgamento no Judiciário, delimitando sua possibilidade de aplicação apenas a casos específicos e excepcionais.
ACESSO À JUSTIÇA COMO INSTRUMENTO DE VALORIZAÇÃO DO TRABALHO HUMANO E COMBATE À ESCRAVIDÃO CONTEMPORÂNEA
Authors: Duque Carolina Caran , Júnior Claudimir Supioni
Published: December 2022

O presente artigo busca analisar de que forma a escravidão afetou o contexto social e jurídico brasileiro e suas consequências atuais, entre elas, a escravidão contemporânea, assim entendida pelo trabalho em condições análogas a de escravo, em grave violação ao princípio fundamental da dignidade da pessoa humana e de que forma o acesso à justiça pode figurar como elemento de transformação social na valorização do trabalho humano e o combate às referidas práticas ilegítimas. Foi utilizada a pesquisa teórico-dogmática, sendo abordados estudos de doutrinadores, jurisprudências e artigos científicos, e em caráter transdisciplinar, informações históricas, sociológicas e dados estatísticos, a fim de sustentar os fundamentos teóricos dos princípios e teorias jurídicas analisadas para o esclarecimento do assunto.
NUEVAS TECNOLOGÍAS, INTELIGENCIA ARTIFICIAL, DERECHO INTERNACIONAL MARÍTIMO Y DERECHOS FUNDAMENTALES
Authors: Torres Manrique Jorge Isaac
Published: December 2022

Las nuevas tecnologías y la inteligencia artificial registran una importante presencia y aporte a la humanidad. Sin embargo, resulta necesario determinar la relación existente entre los mismos y el derecho internacional marítimo, así como, con los derechos fundamentales. En la presente entrega el autor se encarga de desarrollar y demostrar la transversalidad entre los derechos fundamentales y los mismos. Vale decir, el abordaje de su interrelación jurídica y extra jurídica.
COVID-19 mRNA vaccine triggering dermatomyositis: A case report
Authors: Awadth Nabaa Ihsan , Faiq I. Gorial , Al-Laylaa Ragad D. , Ismail Mustafa
Published: December 2022

The battle against SARS-COV-2 is rising and the hope in the safety and effectiveness of immunization against this virus is growing up, even though serious and severe adverse events are scarcely observed. In this article, we report a case of mRNA vaccine induced an autoimmune dermatomyositis with features of severity that are managed by immunosuppressants medications and still in regular follow-up. Inflammatory dermatomyositis can be triggered after vaccination with COVID vaccine in the same mechanism that COVID-19 infection-induced myositis.
Development of preparedness to respond to intimate partner violence scale among mental health professionals
Authors: Vranda Mysore Narasimha , Janardhana Navaneetham , Kumar Channaveerachari Naveen
Published: December 2022

Objectives:

Violence against women has been associated with serious health and mental health consequences. Health-care professionals play an important role in screening and providing care and support to victims of intimate partner violence (IPV) in the hospital setting. There is no culturally relevant tool to assess the mental health professional (MHP) preparedness to screen for partner violence in the clinical setting. This research aimed towards developing and standardizing scale to measure MHP preparedness and perceived skills in responding to IPV in the clinical setting.

Materials and Methods:

The scale was field tested with 200 subjects using consecutive sampling at a tertiary care hospital.

Results:

The exploratory factor analysis resulted in five factors constituting 59.2% of the total variance. The internal consistency Cronbach alpha 0.72 for the final 32-item scale was highly reliable and adequate.

Conclusion:

The final version of the Preparedness to Respond to IPV (PR-IPV) scale measures MHP PR-IPV in the clinical setting. Further, the scale can be used to evaluate the outcome of IPV interventions in different settings.
Automated handling of complex chemical structures in Z-matrix coordinates - the chemcoord library
Authors: Weser Oskar , Hein-Janke Björn , Mata Ricardo
Published: December 2022

In this work, we present a fully automated method for the construction of chemically meaningful sets of non-redundant internal coordinates (also commonly denoted as Z-matrices) from the cartesian coordinates of a molecular system. Particular focus is placed on avoiding ill-definitions of angles and dihedrals due to linear arrangements of atoms, to consistently guarantee a well-defined transformation to cartesian coordinates, even after structural changes. The representations thus obtained are particularly well suited for pathway construction in double-ended methods for transition state search and optimisations with non-linear constraints. Analytical gradients for the transformation between the coordinate systems were derived for the first time, which allows analytical geometry optimizations purely in Z-matrix coordinates. The geometry optimisation was coupled with a Symbolic Algebra package to support arbitrary non-linear constraints in Z-matrix coordinates, while retaining analytical energy gradient conversion. Sample applications are provided for a number of common chemical reactions and illustrative examples where these new algorithms can be used to automatically produce chemically reasonable structure interpolations, or to perform non-linearly constrained optimisations of molecules.
Adsorption of Carbamazepine in All-Silica Zeolites Studied with Density Functional Theory Calculations
Authors: Fischer Michael
Published: December 2022

The anticonvulsant drug carbamazepine (CBZ) is an emerging contaminant of considerable concern due to its hazard potential and environmental persistence. Some previous experimental studies proposed hydrophobic zeolites as promising adsorbents for the removal of carbamazepine from water, but only a few framework types were considered in those investigations. In the present work, electronic structure calculations based on dispersion-corrected density functional theory (DFT) were used to study the adsorption of CBZ in eleven all-silica zeolites having different pore sizes and connectivities of the pore system (AFI, ATS, BEA, CFI, DON, FAU, IFR, ISV, MOR, SFH, SSF framework types). It was found that some zeolites with one-dimensional channels formed by twelve-membered rings (IFR, AFI) exhibit the highest affinity towards CBZ. A “good fit” of CBZ into the zeolite pores that maximises dispersion interactions was identified as the dominant factor determining the interaction strength. Further calculations addressed the role of temperature, performing DFT-based molecular dynamics simulations for selected systems, and of guest-guest interactions between coadsorbed CBZ molecules. In addition to predicting zeolite frameworks of particular interest as materials for selective CBZ removal, the calculations presented here also contribute to the atomic-level understanding of the interaction of functional organic molecules with all-silica zeolites.
Non-collinear magnetism in the post-perovskite thiocyanate frameworks CsM(NCS)3
Authors: Geers Madeleine , Lee Jie Yie , Ling Sanliang , Fabelo Oscar , Cañadillas-Delgado Laura , Cliffe Matthew J.
Published: December 2022

AMX3 compounds are structurally diverse, a notable example being the post-perovskite structure which adopts a two-dimensional framework with corner- and edge-sharing octahedra. Few molecular post-perovskites are known and of these, none have reported magnetic structures. Here we report the synthesis, structure and magnetic properties of molecular post-perovskites: CsNi(NCS)3, a thiocyanate framework, and two new isostructural analogues CsCo(NCS)3 and CsMn(NCS)3. Magnetisation measurements show that all three compounds undergo magnetic order. CsNi(NCS)3 (Curie temperature, TC = 8.5(1) K) and CsCo(NCS)3 (TC = 6.7(1) K) order as weak ferromagnets. On the other hand, CsMn(NCS)3 orders as an antiferromagnet (Néel temperature, TN = 16.8(8) K). Neutron diffraction data of CsNi(NCS)3 and CsMn(NCS)3, show that both are non-collinear magnets. These results suggest molecular frameworks are fruitful ground for realising the spin textures required for the next generation of information technology.
Global potential energy surface and dynamics for the OH + CH3OH reaction
Authors: Espinosa-Garcia Joaquin , Rangel Cipriano
Published: December 2022

Using as functional form a combination of valence bond and mechanic molecular terms a new full-dimensional potential energy surface was developed for the title reaction, named PES-2022, which was fitted to high-level ab initio calculations at the coupled-cluster singles, doubles and perturbative triples-F12 explicitly correlated level on a representative number of points describing the reactive system. This surface simultaneously describes the two reaction channels, hydrogen abstraction from the methyl group (R1 path) and from the alcohol group (R2 path) of methanol to form water. PES-2022 is a smooth and continuous surface which reasonably describes the topology of this reactive system from reactants to products, including the intermediate complexes present in the system. Based on PES-2022 an exhaustive dynamics study was performed using quasi-classical trajectory calculations under two different initial conditions: at a fixed room temperature, for direct comparison with the experimental evidence and at different collision energies, to analyse possible mechanisms of reaction. In the first case, the available energy was mostly deposited as water vibrational energy, with the vibrational population inverted in the stretching modes and not inverted in the bending modes, reproducing the experimental evidence. In the second case, the analysis of different dynamics magnitudes (excitation functions, product energy partitioning and product scattering distributions), allows us to suggest different mechanisms for both R1 and R2 paths: a direct mechanism for the R2 path versus an indirect one, related with “nearly-trapped” trajectories in the intermediate complexes, for the R1 path.
Mersin Üniversitesi Hastanesinde üroonkolojik cerrahi geçiren hastaların analizi
Authors: BAŞARANOĞLU Mert , TUNÇ Veysi , BOZLU Murat , YUYUCU KARABULUT Yasemin , ARSLAN Gözde , AKBAY Erdem , ULUSOY Ercüment , ÇAYAN Selahittin , DORUK Hasan Erdal , ERDEM Erim , TEK Mesut
Published: December 2022

Amaç
Bu çalışmada amaç Mersin Üniversitesi Tıp Fakültesi Hastanesi Üroloji Anabilim Dalı’nda 2010-2020 yılları arasında tanı alan ve/veya tedavi edilen ürogenital kanser hastalarının yaş, cinsiyet, histopatolojik tipleri ve yıllara göre dağılımının değerlendirilmesidir.
Yöntem
Mersin Üniversitesi Tıp Fakültesi Hastanesi Üroloji Anabilim Dalı’na Ocak 2010-Haziran 2020 tarihleri arasında başvuran ve cerrahi müdahale sonucunda alınan doku örneklerinin patoloji raporu malignite lehine yorumlanan hastaların kayıtları incelenmiştir. Söz konusu bu retrospektif veriler hastanemiz Patoloji Anabilim Dalı tarafından hazırlanmış olan ve hastanemiz bilgi veritabanında muhafaza edilen raporlardan elde edilmiştir. Çoklu raporlara sahip hastaların mükerrer kayıtları elenmiştir. Nüks veya progresyon gösteren hastaların ya da birden çok opere edilen hastaların verilerinden en kapsamlı olanları seçilmiştir.
Bulgular
2010-2020 yılların arasında anabilim dalımızca opere edilen 4852 hastadan operasyon sonucundan alınan örnekler Patoloji Anabilim Dalında çalışılmış olup sadece malignite lehine yorumlanan 2000 hastaya ait veri çalışmaya dahil edilmiştir. Elde edilen verilerin analizi sonucu; hastanemizde tüm ürogenital kanserler arasında prostat, mesane, böbrek ve testis kanseri hastalarının sayısı Türkiye ortalamasının üzerinde bulunurken; adrenal bez, üreter ve penis kanserli hastaların sayısı Türkiye ortalamasının altında bulunmuş olup, tüm bu farklar istatistiksel olarak anlamlı bulunmamıştır.
Sonuç
Bu çalışma ile Çukurova bölgesinde hizmet vermekte olan hastanemizde tanı alan hastaların analizlerinin, hem literatüre hem de bölgemizde yapılan sağlık planlamalarına katkı sağlayabileceği kanaatindeyiz.
Yardımcı üreme tekniklerinin ikiz prematürelerin morbidite ve mortalitesine olan etkisi
Authors: CERAN Burak , ÇAKIR Ufuk , TUĞCU Ali Ulaş , TAYMAN Cüneyt
Published: December 2022

Amaç: Yardımcı üreme tekniği (YÜT) sonucu oluşan gebeliklerden doğan ikiz bebeklerin spontan gebelik sonucu olan ikiz bebeklere oranla klinik olarak daha riskli olduğu düşünülmektedir. Ancak YÜT gebelikler sonucunda doğan prematüre bebeklerdeki riskler konusunda bilgiler sınırlıdır. Çalışmamızda YÜT ve spontan gebeliklerden doğan ikiz prematüre bebekler klinik sonuçlar açısından karşılaştırıldı.
Materyal ve metot: Çalışmamıza Eylül 2019 ile Eylül 2020 tarihleri arasında ünitemizde yatan ve 32. gebelik haftası altında doğan tüm ikiz prematüre bebekler dahil edildi. Spontan ve YÜT gebelikler sonucunda doğan prematüre ikiz bebeklerin demografik ve klinik sonuçları karşılaştırıldı.
Bulgular: Çalışmaya spontan ikiz grubunda 116 (81.6%) ve YÜT ikiz grubunda 26 (18.4%) olmak üzere toplam 142 prematüre ikiz dahil edildi. YÜT ve spontan ikiz grupları arasında demografik ve klinik özellikler benzer olarak bulundu (p>0,05).
Sonuç: Çalışmamızda YÜT gebelikler sonucu doğan prematüre bebeklerin spontan olanlara göre ek riske sahip olmadıkları saptandı. Bu sonuç prematürelerde klinik sonuçların ana belirleyicisinin gebelik haftası ve doğum ağırlığı olduğunu göstermektedir.
Sıçanlarda 6-n-propil-2-tiourasil ile bozulan öğrenme ve bellek performansına selenyumun etki
Authors: KOŞAR Bilal , TAN Burak , ALTUNKAYA Melek , SÜER Cem , DURSUN Nurcan
Published: December 2022

Amaç: Bu çalışma ile sıçanlarda 6-n-propil-2-tiourosil (PTU) ile hipotiroidi oluşturularak bozulan uzamsal öğrenme ve bellek performansına selenyumun (Se) iyileştirici etkisini ortaya koymak amaçlanmıştır.
Gereç ve Yöntem: Çalışma vücut ağırlıkları 250-300 gr olan, genç erkek Wistar albino sıçanlar üzerinde yapıldı. Sıçanlar kontrol (Kontrol), hipotiroidi (PTU), PTU ile berabler 5 ppm Se verilen (P-5Se) ve PTU ile berabler 10 ppm Se verilen (P-10Se) olarak dört gruba ayrıldı. Sıçanların plazma sT3, sT4 değerleri ELİSA yöntemiyle, hipokampus Se değerleri ise atomik absorpsiyon spektrometresi ile ölçüldü. Öğrenme/bellek performansının değerlendirilmesi için Morris su tankı testi (MST) kullanıldı.
Bulgular: Öğrenme testinin ilk gününden dördüncü güne doğru tüm grupların yüzme mesafelerinde ve kaçış sürelerinde anlamlı düzeyde azalma görüldü. Gruplar arası istatistiksel karşılaştırmada yüzme mesafesi uygulamanın birinci gününde hipotiroidili grupta kontrole göre artış, Se verilen hipotiroidili gruplarda azalma bulundu. Hedef kadranda bulunma oranı hipotiroidi ile azalma, 5 ppm Se verilen grupta, Se verilmeyen hipotiroidili gruba göre artış gösterdi.
Sonuç: Bu çalışma hipotiroidinin hipokampal öğrenme ve bellek fonksiyonunu olumsuz etkilediğini, selenyum takviyesinin ise hipotirodinin bu olumsuz etkisini düzelttiğini ortaya koymuştur.
The Impact of AUKUS in Indonesian Perspective: Regional Military Balance and Security Dilemma
Authors: Nurfauzi Alifsar , Lampita Frisca , Mahendra Muhammad Rizky
Published: December 2022

Indonesia in issuing Australia’s plans to pursue nuclear-powered submarines and the launch of AUKUS as a new security grouping between Australia, the United Kingdom, and the United States aimed at promoting greater defense industry cooperation will be significant considerations for Indonesia. As one of Australia’s major neighboring country, one of Indonesia major concerns will be the significant impact on the region’s military balance. Not only will Australian nuclear-powered submarines will be able to undertake long-endurance, high-speed, stealth operations, but they could be equipped with upgraded missile systems. The Indonesian government viewed the submarine decision ‘cautiously’ and was ‘deeply concerned’ over the continuous arms race and power projection in the region.
The aim of this paper is to analyze how Australia’s decision to power up its maritime capability create a security dilemma for Indonesia that left Indonesia ‘jammed’ between two major powers. This could increase the tension in the region. As Indonesia believe the AUKUS will provoke China into developing more sophisticated anti-submarine which would generate anxiety for Jakarta. This could lead into arms race between major powers.The author uses qualitative research to find fact and answer research questions on Indonesia’s concern regarding AUKUS will trigger China and provoke arm race in the region and create security dilemma for Indonesia.
Prevención de la preeclampsia y sus complicaciones
Authors: Araujo Silva José Andrés , López Vera Gema Teresa , Vera Proaño Juan Diego , Saldarriaga Vélez Maria Elicenia
Published: December 2022

La preeclampsia es una condición y complicación del embarazo humano que representa un serio peligro para la mujer y su feto. Su caracterización consiste en un surgimiento de hipertensión arterial reciente, o el agravamiento de una preexistente, más una condición de proteinuria después de las 20 primeras semanas de gestación. El objetivo del presente estudio es aportar conocimientos actualizados en relación a la preeclampsia, sus complicaciones y prevención, dado que todavía represente un importante trastorno hipertensivo que puede llegar a exponer a serios riesgos a una gestante y el feto. En razón de ello, se dispuso adelantar un estudio de diseño bibliográfico y una metodología de revisión. Los resultados incluyen: definiciones de preeclampsia, causas, factores de riesgo, complicaciones y prevención. Se concluye que la preeclampsia representa una enfermedad específica del embarazo humano, pero de desconocida etiología, y puede catalogarse como leve o grave. Básicamente consiste en una HTA de comienzo reciente o, del agravamiento de una HTA preexistente al estado de gestación, que, junto a una proteinuria, se manifiesta después de las 20 semanas de gestación. No obstante, la PE también puede evolucionar luego del parto. Las complicaciones asociadas a la PE son varias, pero la mayoría de los tratadistas comparten que entre las más representativas están: restricción (retraso) del crecimiento fetal; nacimiento prematuro, desprendimiento de la placenta, síndrome de HELLP, convulsiones (Eclampsia), daño a otros órganos, enfermedad cardiovascular, problemas de sangrado, ruptura del hígado, BPN y, con menor frecuencia, la muerte. No hay ningún método seguro para prevenir la PE. Aun así, entre los expertos, se comparte como criterios preventivos el uso de la aspirina (Ácido Acetilsalicílico - AAS) en dosis bajas que pueden oscilar entre 60y 150 mg por día; al igual que la ingesta diaria de un suplemento de calcio, si los valores del mismo se encuentran bajos
Ground improvement techniques applied to very soft clays: state of knowledge and recent advances
Authors: Almeida Marcio , Marques Maria , Riccio Mario , Fagundes Diego , Lima Bruno , Polido Uberescilas , Cirone Alessandro , Hosseinpour Iman
Published: December 2022

Soft ground improvement techniques have evolved substantially in Brazil in recent years. However, their application in soft and very soft clays requires a good understanding of the fundamentals of ground improvement techniques suited to the problem as well as the actual field behavior when implemented on a real scale. This paper describes some of the most widely used ground improvement techniques in the context of very soft clays in Brazil. The techniques described in the paper use prefabricated vertical drains (PVD) such as vacuum preloading; or combine PVD and rigid inclusion, such as CPR grouting; or are purely column-like elements such as piled embankments (including those executed with the deep mixing technique, DSM); or combine column-like elements with the drainage function, such as stone columns and geosynthetic encased columns; or use cementitious binders such as shallow soil mixing. The paper reference condition is a soft clay foundation in which no strengthening is implemented, such as, an embankment with basal reinforcement or soft clay with vertical prefabricated drains, or the use of vacuum preloading to speed up the consolidation rate. The applications of the ground improvement techniques are illustrated by case histories, numerical analyses, or physical models. Different types of measurements are used to evaluate the performance of each technique, including settlements, horizontal displacements, excess pore pressures, embankment applied stresses, stress concentration factors, and clay strength following the ground treatment. The settlement improvement factor β, the ratio between the settlements for untreated and treated conditions, is shown to be a suitable parameter to assess the degree of improvement imposed in the soft foundation by ranking the various methods in increased order of strengthening effect.
AGRO-ECONOMIC IMPACT OF ORGANIC MULCHES ON WEED DYNAMICS AND PRODUCTIVITY OF RAINFED WHEAT (Triticum aestivum L.)
Authors: Raza Ali
Published: December 2022

Wheat is a widely grown cereal crop under rainfed conditions of semi-arid areas of the world including Pakistan. Unfortunately, its yield remains low due to heavy weed infestation and scarce moisture supply in the root zone from erratic rainfall. Therefore, a field experiment was conducted to observe the influence of different organic mulches on the soil moisture, weeds, growth and yield of wheat crop. Four organic mulches i.e wheat straw sawdust, rice straw and rice husk were applied up to 2 inches surface layer between the rows of wheat crop.  Application of wheat straw mulch conserved the highest soil moisture (72.3%) at 0-15cm depth six weeks after sowing and caused maximum weed suppression with 81.17% weed control efficiency and 63.70% weed control index as compared to unmulched control. Maximum plant height (70.8cm), productive tillers (137.33 m-2), grain weight per spike (2.37g), grains per spike (52.3), 1000-grain weight (50.66 g), biological yield (9393.9 kg ha-1), grain yield (3665.6 kg ha-1), harvest index (38.60%) and benefit-cost ratio (1.69) were observed in rainfed wheat crop treated with wheat straw mulch. Wheat crop total rainfall use efficiency followed the order of wheat straw > rice straw > saw dust> rice husk> control. The highest weed density and dry weight while lowest soil moisture and grain yield were recorded with no mulch and rice husk treatments.
THE IMAGE OF A NURSE IN SOVIET AND POST-SOVIET CINEMA
Authors:   Russian State University for the Humanities, Nechaeva Elizaveta O.
Published: December 2022

The article provides an analysis of the transformation in the film image of a nurse in the Soviet and post-Soviet times. The nursing staff is the most numerous in the entire hierarchy of physicians. Increasing the number of young people entering medical schools will greatly reduce the shortage of personnel in the industry, but it requires an increase in the status of a medical worker. Cinema serves as a reliable tool for shaping public opinion, constructing it purposefully and systematically. The article shows that over the past decades, there has been a change in moral and ideological principles, attitudes of the professional group as well as the artistic image of the hero, his characteristic features are changing, and as a result, public opinion is also being transformed, following the cultural narrative in the form of cinema. The author refers to the Soviet cinematographyin which heroes with high ideals and landmarks came to the fore. Over the next three decades, the image of the hero (medical worker) in the new Russia changed. The author gives a description of the storylines and characters of especially significant and popular films in order to understand how the audience sees the characters - nurses, and how, because of that public opinion can be influenced.
DASEIN И ἦΘΟΣ: ФАКТИЧНЫ ЛИ ЦЕННОСТИ?
Authors:   Russian State University for the Humanities, Vishnyakov Vladimir P.
Published: December 2022

The article considers M. Heidegger’s deconstruction of the metaphysical foundations for the moral philosophy of modern times. Heidegger’s interpretation of Aristotle (together with an analysis of early Christianity) offers an original version of ontology combined with ethics. In such optics, Being and Time, like Nicomachean Ethics, is an ethical treatise: it is also based on an understanding of human ethos (from the Greek ἦθος, “temper, character, nest”) and reveals the characteristics of life structured by “proper”. During the Age of Enlightenment (17th–19th centuries), a paradigm shift occurred in the field of practical philosophy, associated with the transition from ethics (that is, ethos as a form of life with its practical and normative dimensions) to moral concepts based on individualism and the distinction between facts and values. The split between ontology and the teachings of morality made impossible any rational substantiation or justification of ethics. Unlike modernist theories of morality, which attempt to express impartial and value-free principles of individual behavior, Heidegger explores the conditions for the possibility of changing lifestyles. His understanding of ethics can be interpreted in an Aristotelian context, in which life in society (that is, being in a “shared world”) determines the ontological conditions that make ethical action possible. The philosopher reveals the existence of Dasein in the context of a certain perfectionist understanding: two modes are found in it, one of which is obviously more valuable (or perfect) than the other – at least due to a wider perspective and deep self-understanding. The fulfillment of “ethics” means revealing an individualizing (“owned”) way of disclosing the world, what implies sensitivity to the call of Being and a readiness in the midst of the world to transform one’s finiteness in order to become a “genuine” member of the historical community. In the ontological structure of Dasein, such way of being is fulfilled in special revealing “moods” (πάθη), which are not reducible either to empirical sensibility or to cognitive functions. The factual enactment of ethical values is expressed in resoluteness, steadfast adherence to the chosen historical heritage, sensitivity to all aspects of the existential situation. These characteristics of revealing “moods” form a list of metacultural virtues that are the basis for mutual understanding and dialogue between representatives of various “ethoses” of a fragmented society.
Especialización productiva en el Estado de Michoacán: Análisis Regional, 2015
Authors: De la Guardia Sayuri , Terrones-Cordero Aníbal
Published: December 2022

El objetivo de esta investigación fue determinar la especialización productiva de las diez regiones que integran el Estado de Michoacán: Lerma Chapala, Bajío, Cuitzeo, Oriente, Tepalcatepec, Purépecha, Pátzuaro-Zirahuén, Tierra Caliente, Sierra Costa e Infiernillo; mediante el cálculo  del Índice de Especialización Económica Regional, utilizando datos de la población ocupada de los sectores primario, secundario y terciario de la Encuesta Intercensal 2015 del Instituto Nacional de Estadística y Geografía (INEGI). Siete de las diez regiones que integran el Estado presentan una especialización productiva ya sea en el sector secundario o terciario. La región Cuitzeo presentó una especialización en el sector terciario, siendo considerada como la más desarrollada.
Estrategias implementadas en departamentos de cirugía pediátrica durante pandemia por COVID-19
Authors: Juárez Cervantes Ana Paula , Cornejo Roldán Laura Rosa
Published: December 2022

Objetivo: Identificar las medidas adoptadas por distintas instituciones en el área de cirugía pediátrica con relación en la atención a pacientes durante la pandemia por COVID-19. Métodos: Se realizó una búsqueda en septiembre de 2021 a través de PubMed Central con cuatro palabras clave: “Cirugía pediátrica, pandemia, COVID-19 y calidad de atención”. Se eligieron veinte artículos en idioma inglés, cuyos trabajos fueron realizados en instituciones de Europa, Asia y América. Se analizaron cada uno de los artículos para identificar la implementación de acciones que permitieran continuar con atención de pacientes en las instituciones involucradas. Material: Veinte artículos, publicados en idioma inglés, de tres continentes. Resultados: Nueve publicados en Europa, cuatro en Asia y el resto de América; se encontraron siete diferentes tipos de acciones para continuar con la atención de pacientes, que fueron: administrativos (19); atención en quirófano (9); integración de equipo de trabajo (8); clasificación de cirugías (electivas o urgencia; 7); estructurales internos (4); método de enseñanza (3); atención en consulta externa (3). Conclusión: El virus SARS-Cov2 ha generado un colapso del Sistema sanitario; afectó de manera importante a la población infantil, sobretodo respecto a los padecimientos quirúrgicos, ya que hay evidencia de la existencia de pánico generada en los padres de estos pacientes, lo que hace que no se realice diagnóstico oportuno y atrase el tratamiento. Asimismo, los médicos residentes en esta área han sido poco adiestrados en procedimientos quirúrgicos. Las modificaciones expuestas en este artículo son una pauta que marca el antes y después de la pandemia.
Manejo de la ansiedad en la atención odontológica en niños
Authors: Ruiz Sanchez Ana Laura , Balderas Delgadillo Carmen , Monjarás Ávila Ana Josefina , Molina Trinidad Eva María , Becerril Flores Marco Antonio
Published: December 2022

La ansiedad dental es la sensación de aprensión sobre el tratamiento dental, que se asocia con un pobre estado de salud bucal; ya que es señalada por muchos pacientes como un motivo para no acudir de forma regular al dentista. De tal forma que los padres del paciente pediátrico tienen un rol muy importante en la atención odontológica, ya que son ellos quienes finalmente toman la decisión de llevar al niño a su cita dental y deciden a qué edad deben hacerlo. 

El origen del problema viene del desconocimiento del paciente pediátrico sobre lo que ocurrirá en la consulta, y en ocasiones pueden llegar a ser los mismos padres de familia quienes transmiten esa emoción a los hijos.

Si el dentista es consciente del nivel de ansiedad de su paciente, entonces puede tomar medidas para ayudar a aliviar la ansiedad durante el tratamiento odontológico. El dentista debe estar comprometido en ayudar al paciente infantil a aprender las formas de manejar este comportamiento. Por ello es necesario generar un lazo de confianza con el paciente pediátrico desde la primera cita; el uso de técnicas y recomendaciones para la disminución de la ansiedad.
Correcto uso de la Taxonomía de Bloom para desarrollar objetivos
Authors: Peñaloza-Carreón Jair Esteban , Mayorga-Ponce Rocío Belem , Roldan-Carpio Adamary
Published: December 2022

El presente resumen se planteó con el fin de dar a conocer la Taxonomía de Bloom del Dr. Benjamin (1956), desde la creación de la taxonomía se han logrado muchos beneficios a nivel intelectual y en la creación de objetivos tanto generales como específicos en el diseño de diferentes trabajos para profesionales de diferentes áreas teniendo en cuenta la jerarquía con la cual se rige esta dicha taxonomía, las cuales se dividen en procesos cognitivos de orden inferior y superior.