bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic Effect of Nano-Extract of Nigella Sativa Seeds on The Histological Structure of The Testis In Male Albino Rats Induced With Anemia
Authors: Hasnawi Noor M. , Mohammed Jabbar Abadi
Published: October 2024

Background: The study explores the effect of nanoparticles derived from the aqueous extract of Nigella sativa seeds on the histological structure of the testis in male albino rats with tartrazine-induced anemia. Nanoparticles, ranging in size from 1 to 100 nanometers, possess unique physical and chemical properties that enhance their ability to interact and deliver drugs. Objective: This study focuses on the therapeutic potential of Nigella sativa seed extract nanoparticles in treating testicular histological changes in anemic rats.  The testicle is an oval organ involved in sperm formation and hormone production. It contains seminiferous tubules, Sertoli cells, and Leydig cells, which are responsible for sperm production and testosterone synthesis. Methods: The study included 36 male albino mice, aged between 8-12 weeks, and weighing 240-260 grams, from the Iraqi Center for Cancer Research and Medical Genetics. The animals were divided into six groups, each group having six animals. Results: The study showed that tartrazine at a concentration of 20 mg/kg: with Nigella sativa nanoparticles 50 mg/kg: an increase in weight. the body. While tartrazine at a concentration of 20 mg/kg with N.sativa  nanoparticles at 75 mg/kg did not show significant differences compared with the control group.  The results showed the Nigella sativa seed nanoparticles at a concentration of (50 mg/kg, 75 mg/kg): showed an increase in body weight, while tartrazine at a concentration of 20 mg/kg: a decrease in body weight, and no significant changes were observed in testicle weight in all treatments compared with the control group. Non-significant changes in testicle weight compare with Control group. The study showed that treatment with tartrazine 20 mg/kg showed noticeable histological changes in the histological structure of the testicle. Tartrazine with N.sativa  nanoparticles (50 mg/kg, 75 mg/kg): No histological changes, indicating attenuation of tartrazine-induced damage. N.sativa  nanoparticles (50 mg/kg, 75 mg/kg): demonstrated normal composition of testicular tissue, indicating no harmful effects on testicular tissue. has protective effects. Conclusion:The study aimed to investigate the potential of using nanoparticles extracted from Nigella sativa seeds to protect against damage caused by tartrazine in male albino rats.with significant therapeutic implications for the use of natural antioxidants in biomedical applications.
Budget by Result and Its Incidence on The Quality of Public Spending Management, in the City of Chincha 2021
Authors: Gutierrez Etheel Romila Becerra , Nuñez Freddy Jhonny Sachun , Cabrejos Ruth Gissela Perez , Kevin Frederick Sachun Becerra
Published: October 2024

The purpose of this study was to clarify the relationship between economic performance and the quality of public spending in the city of Chincha in the year 2021. This study used a non-experimental, cross-sectional, descriptive, causal design with a quantitative approach. The sample consisted of 60 government officials from the Chincha health sector. The data collection technique was used, questionnaires as tools to evaluate these two variables. The value of Nagelkerke's pseudo R2 (0.346) depends on 34.6% of the uncertainty related to the quality of the administration costs. public finance. by results Indicators measure the amount and rate of spending, limited skills, the persistence of corruption, financial allocation performance, and evidence of a narrow health gap, rather than the quality of spending that the industry does not it can be better.rea.
Relationship between Clinicopathological Factors of Breast Cancer and Lymph Node Metastasis in Young Women
Authors: Halim Zuvar Faza , Kartini Diani
Published: October 2024

Aim : To determine the incidence of lymph node metastasis in breast cancer of young women and its relationship with clinicopathologic factors. Methods : The study used an analytic observational design and a cross-sectional approach. Bivariate analysis was performed with Fisher's exact probability test to determine the association of clinicopathologic factors with lymph node metastasis. Results: N1 lymph node metastases could be found in most of the young women breast cancer patients at 42.9%, followed by N3 and N2 at 11.4% and 8.6%, respectively. On the other hand, 37.1% of patients showed no lymph node metastasis. Fisher's exact probability test showed that of the six clinicopathological factors, only tumour size was associated with lymph node metastasis with a p-value of 0.031. Conclusion : The incidence rate of lymph node metastasis in breast cancer of young women was 42.9% for N1, 11.4% for N3, and 8.6% for N2. There was a significant association between tumour size and lymph node metastasis.
Comparative Analysis of Waiting and Consultation Times in Convenient Care Clinics versus Traditional Family Practice: A Systematic Review
Authors: MD Anwar Alrashed , Mohamed Hany Ramadan
Published: October 2024

This systematic review aims to evaluate and compare waiting and consultation times between convenient care clinics (CCCs) and traditional family practice physician offices, with a focus on their impact on patient satisfaction and healthcare delivery efficiency. The review synthesizes data from various studies to assess differences in patient waiting times, consultation durations, and overall satisfaction between these two healthcare settings. A comprehensive search of electronic databases including PubMed, Cochrane, Web of Science, and MEDLINE was conducted to identify relevant studies. Data extraction focused on waiting times, consultation times, patient satisfaction, and any variations based on time of day or healthcare setting. The review found that CCCs generally offer shorter waiting times compared to traditional family practices, enhancing immediate access to care. However, consultations in CCCs were typically longer. Patient satisfaction was higher in CCCs due to reduced waiting periods. The study highlights the effectiveness of CCCs in improving access and patient satisfaction, while also indicating the need for a balance between immediate care and the depth of consultations provided. Further research is needed to explore how these findings can inform improvements in healthcare delivery across various settings.
Diabetes Mellitus and Respiratory Function in Smokers Eligible for Coronary Artery Bypass Grafting
Authors: PhD Maqdad Taaqi, , PhD Hesham N Alrowayeh, , PhD Sameera H Aljadi, , PhD Hanan Ahmad Alfadhli,
Published: October 2024

Diabetics' respiratory systems are characterized by fibroblast and vascular endothelial proliferation, increased density of pulmonary microspheres, and thickening of pulmonary vesicle walls due to increased collagen and elastin. These sorts of damage to the alveolar-capillary barrier, as well as reductions in pulmonary capacity and flow, hurt the body's functionality. Investigate the possible links between diabetes and respiratory parameters in smokers who are candidates for coronary artery bypass grafting. Assess early changes in lung volumes in smoking individuals before and after CABG using pulmonary function tests and determine how diabetes may influence these changes by comparing diabetic and non-diabetic patients. This was a prospective controlled study of 200 consecutive individuals who underwent elective coronary artery bypass surgery. Two hundred fifty-six patients were accepted to our study, but 56 were excluded (41 did not match our inclusion criteria, and 15 declined to participate), leaving us with 200 cases. There was a statistically significant difference between diabetes and non-diabetic subjects on lung function testing. Patients with diabetes who qualified for CABG showed poorer spirometry parameters than those without diabetes. This suggests that these individuals require respiratory examinations and treatment to improve their respiratory performance before and following cardiac surgery.
Study Soil Contamination Surrounding The Brick Factory In Al- Saniyah/ Al- Diwaniyah / Iraq
Authors: Kadhim Melak Salim , Hussain Lujain Ibrahim
Published: October 2024

The study was conducted on the effect of the brick factories in Saniyah on the surrounding soil, with dimensions of 50 m, 500 m, and 1000 m, depending on the direction of the prevailing winds and opposite to the direction of the prevailing winds as well, at 50 m, 500 m, and 1000 m. The concentrations of lead and copper were measured in the soil in two phases : exchangable and residual. The highest concentrations were for lead in the winter. In the alternating part towards the wind, it reached 36.15, and the lowest concentration was in site 5, opposite the direction of the wind. As for the copper element, its highest value was 4.76 in the third site towards the wind, and the lowest value was 1.1 at a distance of 50 m from the chimney, against the direction of the wind. We note that for both elements, the residual phase value is higher than The value of exchangable phase in the direction of the wind is higher than in the opposite direction.
Single Dose of Chloroform Induces Hepatic Dysfunction with Pro-Inflammatory Cytokines Response in Vivo
Authors: Ghareeb Ozdan Akram , Sheikhzadeh Sanaz
Published: October 2024

Chloroform (CH) is considered an urgent environmental pollutant that leads to critical health effects. This investigation was carried out to verify the involvement of serum cytokines in the hepatic dysfunction induced by single exposure to CH in laboratory rats. Eighteen adult male laboratory rats were separated into three groups of eight rats each. Control (CON) group included animals without any treatment, while the rest of the two groups were administrated trichloromethane at a dose of 477 mg/kg , orally then sacrificed after 1 day (CH-1) and 7day (CH-7) post-exposure. The results indicated that single-dose exposure induced liver dysfunction through significant elevation of serum activities of hepatic enzymes compared with unexposed control rats. Furthermore, chloroform intoxication caused a significant time-dependent rise in concentrations of some pro-inflammatory cytokines in serum of exposed rats. In conclusion, a single high dose of chloroform causes liver dysfunction and promotes the response of pro-inflammatory cytokines in rats.
Estimated of Pomegranate Peel Waste for Biosorption of Cu (II) & Pb(II) Ions From Aqueous Solutions
Authors: Abid Mohammed kadhem , Askar Ahmed S. Abd , Abdulhasan Mahmood Jamal
Published: October 2024

This study intends to explore the waste natural materials’ adsorption capability. The use of pomegranate peels was investigated to see the chances of eradicating Pb(II) and Cu(II) ions from the aqueous solutions. Adsorption capability was evaluated using batch adsorption experiments, which also evaluated the impact of solution pH and initial metal concentration. The ideal biosorption conditions included a pH of 6.0, a dose of 0.1 g of biomass, and an equilibrium duration of 90 minutes. The adsorption data fit in a way that was comparable to the isotherm models by Freundlich and Langmuir. Pomegranate peel (PGP) was tested for its affinity and adsorption capability. Based on the values of the separation factor (RL) and Freundlich constant (n), it seems that the metal ions were taken up onto biosorbents in a preferred manner. According to this study's conclusions, the equilibrium data suit the Freundlich and Langmuir isotherms rather nicely. According to correlation coefficient data, the maximal sorption capacity of the produced pomegranate peel is 5000 mg/g. The Fourier Transform Infrared Spectrometer (FTIR), Energy Dispersive X-ray Spectrometer (EDX), and Scanning Electron Microscope (SEM) were utilised in the characterisation examinations. As a result, distinct aggregates formed on the surface of the biosorbent. In the characterisation experiments, an energy-dispersive X-ray spectrometer (EDX) and a scanning electron microscope (SEM) were employed. Different aggregates developed on the biosorbent surface as a result of contact with metal ions. On the surface of the biosorbent, distinct aggregates formed as a result of interaction with metal ions. Either via complexation or electrostatic attraction, the metal ions attached themselves to the biosorbents' active sites.
Effect of Social Support and Spiritual Well-being on the Quality of Life of Patients Undergoing Hemodialysis
Authors: A.Yaseen Al-Khaqani, Mustafa , AL-Fayyadh Sadeq
Published: October 2024

Background: This study aims to assess the impact of social support and spiritual well-being on the quality of life of patients undergoing hemodialysis. Methods and Materials: A cross-sectional research design was adopted in Iraq, with 234 purposively selected patients, meeting the inclusion criteria. Kidney Disease, Quality of Life Short Form Version 36 (QOL SF-36) scale, the Multi-Dimension Perceived Social Support Scale (MDPSS), and the spiritual well-being scale (SWB) were used. Results: The regression model demonstrates a significant effect of social support and spiritual well-being (SWB) on the QOL. This can be inferred from the t-value that shows the differences between social support and QOL = (1.434), as also, as the differences between SWB and QOL = (1.906), and its associated p-value (0.038, 0.015). By referring to F (2,231) = 3.14 and its p-value = 0.034. All these explain the variations in the quality of life and the explanatory variables are referred to as R2 value = 0.45. Both variables added were statistically significant to the prediction, p < 0.05. Conclusion: The quality of life of patients undergoing hemodialysis was influenced by social support and spiritual well-being. Although the level of social support and spiritual well-being was high among the study participants, the quality of life was moderate.
Effect of Hamstring Active Release Technique in Cervicogenic Headache
Authors: Mohammed Samar A. , Sayed Wadida H. El , Atta Hanaa K. , Abdallah Ghada A.
Published: October 2024

Objectives: To investigate the effect of Hamstring active release technique on pain intensity level, headache intensity, pressure pain threshold, cervical flexion rotation range of motion and Hamstring flexibility in patients with cervicogenic headache. Methods: Fifty-six patients with cervicogenic headache participated in the study, aged 25-45 years. Patients were randomized into two groups of 28 individuals each. Group A was given conventional physiotherapy only in the form of ultrasonic therapy, stretching as well as strengthening exercises. Group B was given conventional physiotherapy and active release technique for Hamstring. Each group was treated three times a week for one month. Pain intensity level, headache intensity, pressure pain threshold of Sub-occipital and Hamstring muscles trigger points, cervical flexion rotation range of motion and Hamstring flexibility were measured by    visual analogue scale, the Arabic version of 6-item headache impact test, digital pressure algometry, CROM device and straight leg raising test respectively, pre and post-treatment. Results: Within group comparison showed significant difference in pain intensity level, headache intensity, pressure pain threshold of Sub-occipital and Hamstring muscles, cervical flexion rotation range of motion and Hamstring flexibility. Between groups comparison showed no significant difference in all variables, pre-study. Where a significant difference in all variables, post study, in favor of group B except right and left cervical flexion rotation range of motion. Conclusion: Hamstring active release technique improves pain intensity level, headache intensity, pressure pain threshold and Hamstring flexibility, in patients with cervicogenic headache.
Exploring the Role of HR Analytics in Enhancing Talent Acquisition Strategies
Authors: Samal Dr Ajatashatru , Sharma Dr. Priyanka , Naveen Dr. Shreevamshi , Kumar K Dr.chethan , Kotehal Poornima U , Dr Thirulogasundaram V P.
Published: October 2024

Hiring and selecting the right candidate is a critical business process in today’s cutthroat competition. HR Analytics, also known as Human Resource Analytics, provides unique insights into talent acquisition and helps organisations to improve their strategies based on fact. This research paper aims to establish the use of the HR Analytics in improving the talent acquisition practices since this will help in identifying the different candidates sourcing, screening, selection, and onboarding processes. In doing so, the work employs the study of different techniques of HR Analytics including but not limited to the predictive analytics, data mining, and talent market analysis with the main view of understanding how different techniques can be used to give the organizations competitive advantage in talent management and attraction. The research will focus on a few real-world solutions such as the use of HR Analytics for social media talent acquisition, the use of prediction models for screening and the use of data analytics for selection. Also, the paper will discuss the problems and drawbacks that may be encountered while adopting HR Analytics in recruiting. In it, we will highlight the data quality issue, the privacy issue, and the need that HR professionals must have skills and knowledge to use the HR Analytics tools. Lastly, this research aims at contributing to the existing body of knowledge that seeks to help organizations that aim at increasing on their Strategic Human Resources Management Talent Acquisition approach based on the design and use of HR Analytics. Day by day organizations are becoming more rational and by using this technique organizations can arrive to better decisions about employer branding and, consequently, about attracting and retaining the best talent in today’s job market.
The Effect Of The Inside And Outside The Circle Strategy On The Achievement Of First-Year Intermediate Female Students In The Subject Of Biology And Deductive Thinking
Authors: Kamel Haneen Hamed , Al-Khafaji Dr.Ibtisam Ja'afar Jawad
Published: October 2024

The purpose of the study is to determine how first-year intermediate school biology students' deductive reasoning is impacted by the inside and outside the circle strategies. The research sample of first-intermediate female students at Al-Rifaa Girls' Secondary School was comprised of two sections (C and D) that were selected at random from nine middle and secondary schools in Babylon that are affiliated with the General Directorate of Education for the academic year 2023–2024. In terms of the factors (chronological age expressed in months, IQ exam, past accomplishment test, and deductive reasoning test), the researcher balanced the two groups in the present study. Seventy-one female students made up the research sample. They were split into two groups: thirty-four students in the experimental group, who will study using a strategy both inside and outside the circle, and thirty-six students in the control group, who will follow standard protocol. The first three units from the biology textbook were among the scientific materials that the researcher recommended should be taught. Following the establishment of parity between the two groups, the researcher created the application criteria for each group for the first intermediate grade. Following the experiment's completion, the researcher used her study instruments on the two groups to collect data and analyze it using a t-test. The results demonstrated the experimental group's advantage over the control group, which was examined using the inside-and-outside-the-circle deductive reasoning technique.
Evaluating the Quality of Screening Process for High-Risk Pregnancies in Paser District, East Kalimantan
Authors: Tinaningsih Morita Dwi , Sulistyowati Sri , Wijaya Mahendra , Fithri An Nisa
Published: October 2024

Health service programme success is measured by maternal mortality. There have been efforts to reduce maternal and neonatal fatalities. Field observations suggest that high-risk pregnancy referral rates are still low, delaying access to better services. Screening for high-risk pregnancies is an operational technique to prevent maternal and newborn emergency issues by allowing early treatment and referral planning. Health cadres and personnel can provide quality information. Lack of knowledge and awareness will harm society, especially pregnant women, in dealing and seeking health care. This study uses descriptive methods to assess high-risk pregnancy screening in Paser Regency, East Kalimantan, by collecting individual data and watching written and verbal behaviour. This research is qualitative and phenomenological. Health workers, ob-gyns, GPs, and pregnant women were informants. The data was collected through interviews from November to December 2023. The research found that high-risk pregnancy screening was still poor due to lack of knowledge, understanding, staff, time, site, and community culture. This research aims to improve high-risk pregnancy screening in Paser Regency, East Kalimantan Province, so that the policy can become permanent and help the planned referral process by motivating, socialising, training health cadres, and requiring cross-sectoral and cross-program support.
The Consequences of Delayed Presentation and Management of Penile Fracture
Authors: Yadgar Mazin Anwar , Akram M. Al-Khazraji  , Abbass Yassir Ismael , Ahmed Azher M.
Published: October 2024

Background of study Penile fractures have traditionally been considered to require immediate surgical intervention. However, recent studies have described acceptable outcomes with delayed repair. In this prospective study, we investigated the consequences of delayed presentation and treatment of penile fractures.
Aim of Study: To assess the outcome of delayed presentation of cases with penile fracture on the long-term outcome of surgical intervention.
Patient and method: A prospective observational study was conducted between January and December 2022 and included 21 patients with penile fractures from multiple centers in Iraq who underwent surgery immediately after admission. To evaluate the outcome of the time to presentation, the patients were divided into two groups: Group A included 13 patients with early presentation within 24 hours (1 to 9 hours, mean = 3.93 hours) and Group B included 8 patients with delayed presentation after 24 hours (33 hours to 5 days, mean = 60.75 hours). All patients underwent routine follow-up at 1, 3, and 6 months after surgery; during this visit, long-term complications were reassessed using questionnaires and local examinations.
Results: Group A included 13 patients (61.9%) and group B included 8 patients (38.1%). In group A, patients presented to the emergency department within 24 hours after penile trauma. In group B, patients presented to the emergency department or clinic within 24 hours after penile trauma. The incidence of long-term complications was 7.6% (1 of 13 patients) in group A and 62.5% (5 of 8 patients) in group B (OR 26.4, 95% CI 4.41–157.86, p = 0.0001). Erectile dysfunction and penile mass did not differ significantly between the two groups (p = 0.67 and 0.06, respectively). However, pain during insertion and erection were higher in group B (50% and 7.6% in group B and group A, respectively) (OR 25, 95% CI 2.69-231.59, p = 0.1). Penile curvature was observed only in the second group (37.5%). However, the curvature was mild and did not affect sexual function.
Conclusion: Immediate surgical repair has the best prognosis and should remain the recommended treatment modality of penile fracture.
Strategic Impact (D.C.A.A.T.A) In Mental Alertness Among Fourth Year Middle School Students In Chemistry
Authors: Hassan Ahmed Hanawi , Al-Anabi Dr. Wafa Abd Al- Razzaq Abbas
Published: October 2024

The eresearch aim.s too iidentify the impact of the strategyy [(D.C.A.A.T.A) in mental alertness among fourth-year middle school students in chemistry].The quasi-experimentall design wass adopted for thee experimentall and controll groupss withi the posttest, where the sample size was (73) students, distributed among (36) forr thee experimentall groupp andd (37) forr thee controll groupp, and too achieve Objective of the research: The researchers built a measure of mental alertness consisting of (28) items according to Langer’s four dimensions. After applying the measure too thee twoo researchh groupp, the researchers analyzed thee results. It became clear thatt thee studentss of thee experimentall groupp were superiorr too thee studentse thee controll groupp according to thee (D.C.A.A.T.A) strategy in the measure of mental alertness, and that The size of the effect of the (D.C.A.A.T.A) strategy was very large on the mental alertness scale, and in light of this, the following conclusion was reached that teaching according to the (D.C.A.A.T.A) strategy contributed to improving thee levell off mental alertness off fourthh-yearr middlee schooll studentss inn chemistry.
Prevalence of Psychological Stress and Associated Risk Factors Among Hypertensive Patients in Jordan: Cross-Sectional Study
Authors: Nour M. Obeidat  , Malek A. Zihlif  , Moath Y. Alqaraleh  , Nour M. Obeidat
Published: October 2024

Hypertension is considered one of the chronic illnesses that affect many individuals across the globe. It has been evident that stress is associated with hypertension. The current study aimed to assess the prevalence of stress among hypertensive men as well as determine the risk factors causing psychological stress in Jordan. This study used a descriptive correlation cross-sectional design. The researchers recruited 200 patients with hypertension from six hospitals located in the central part of Jordan. Data was collected from the participants through self report questionnaire. The study results revealed that the total scores of perceived stress among the study participants ranged from 4 to 42 (M= 18.17; SD= 8.18). Almost half of the study participants (40%) perceived normal level of stress (0 ≤ total stress subscale ≤ 14). The findings showed that gender (t = -1.99, B = -2.90, p = 0.048), educational Level (t = -2.39, B = -2.39, p = 0.02), health Status (t = 3.08, B = 1.67, p = 0.002), and sleep (t =2.45, B = 3.22, p = 0.02) were the significant predictors of stress among Jordanian patients with hypertension. This study contributed to the existing body of knowledge and can be considered as a baseline for future researcher in the area of stress. The health care providers in various medical departments should make effort to provide optimal care for patients with hypertension that directed toward decreasing the level of stress.
Digital Markets Dynamics and Ethical Considerations of Online Drug Sales via Cryptomarkets
Authors: Nadiia Horobets  , Oleg Reznik  , Alina Riamzina  , Roman Samsin  , Sergii Denysenko
Published: October 2024

The article is devoted to a topical topic – the analysis of a new way of selling drugs via the Internet and using cryptocurrency. In the article, the authors analyzed the Internet as a medium for drug trafficking; the composition of the criminal offense, which consists of the illegal sale of drugs; the social conditionality of criminalization of drug trafficking via the Internet; trends in the use of cryptocurrencies for drug trafficking; money laundering from drug trafficking through cryptocurrencies and measures to combat drug trafficking online and through cryptocurrency. It is emphasized that the appearance of this way of selling drugs is due to the development of technologies and their undoubted advantages, which criminals, from small fraudsters to criminal groups, adapt to carry out illegal activities. The number of people who buy illegal drugs on the dark web is gradually increasing; more and more buyers prefer to pay with cryptocurrency, and criminals are trying to legalize the proceeds of drug crime through the crypto market. All this indicates the increased social danger of such drug trade compared to other forms of their sale due to significant profits, the involvement of a large number of consumers, and direct and hidden effects on the growth of a country: public health issues, organized crimes, security concerns, etc. However, the fight against drug trafficking on the Internet and with the use of crypto-currency has not been properly regulated at the national and international levels. Considering this to fight against such actions effectively, the following is necessary today: an official definition of the status of cryptocurrency in legislation and the development of new methods, tactics, and technologies for the investigation of crimes. Drug business on the Internet and through cryptocurrencies, which will consider the latter's peculiarities and will be constantly updated in accordance with the pace of evolution of digital currencies; establishment of cooperation of cryptocurrency exchanges, financial institutions, regulators, law enforcement agencies, and technology providers.
Limits of Interference into the Human Genome
Authors: Hanna Krushelnytska  , Olha Bodnar-Petrovska  , Tetiana Fedorenko  , Olga Pravotorova  , Olesia Batryn  , Oleg Predmestnikov
Published: October 2024

Introduction: The use of advances in genomics in practical medicine can positively affect the quality of services in the healthcare sector, as well as the results of applied medical research.
Objectives: The purpose of the article is to research regulatory and scientific approaches to the concept of the human genome as an object of legal relations, as well as to determine the limits of interference into a human being’s genomic integrity.
Materials and methods: Regarding the chosen subject matter of research, the author while preparing the scientific article has used materials of international regulatory legal acts, Ukrainian and foreign legal literature. To achieve the set aim, the author has used general scientific and special methods of scientific cognition. These methods combined with the scientific principles of objectivity, scientificity and reasonableness, have provided a comprehensive research of the limits of interference into the human genome.
Results: The concept of the human genome, as well as its material and non-material components, have been studied from a biological and legal point of view. The private and legal nature of the human genome as a personal non-property good has been defined. The concept of the individual’s integrity, enshrined in international regulatory legal acts, has been analyzed from the point of view of its coverage of a human being’s genomic integrity. It has been established that a violation of genomic integrity is possible both by the intentional actions of third parties and as a result of genome changes due to the action of natural factors. The concepts and types of the human genome editing have been defined. The potential reasons for banning the editing of human germline cells have been critically analyzed. The legal nature of interference into the human genome from the point of view of eugenical practices has been studied. The author has studied the possibility of classifying the use of vaccines on the mRNA platform as interferences into the human genome.
Conclusions: It has been concluded that there is a need to recognize the human genome as a personal non-property good, and, accordingly, as an object of private rights. The author has stated own point of view on the inadmissibility of arbitrary interference into human genomic integrity and the existing types of interference into the human genome.
Relationship Between Happiness, Culture, Socio-Economic Status, And Religious Coping Among Muslim Women Students Residing In Sokoto State, Nigeria
Authors: Zainab Lawal Ibrahi  , Abdulmumini INDA  , Aqeel Khan  , Sanitah Bte Mohd Yusof  , Noor Azean Binti Atan
Published: October 2024

The goal of happiness is to have a stress-free and functional society. Yet, stress from cultural and socio-economic factors may arise when Muslim women student’s issues are discussed within society practices; which has resulted in illiteracy in Nigeria due to low enrolment attendance and school completion rates. Despite this, the World Happiness Report (WHR, 2023) ranked Nigeria as 95th happiest country in the world, and the fifth happiest country in Africa. Nevertheless, not many researches on happiness among Muslim women students in Northern Nigeria have been reported. This study investigated the relationship between happiness, culture, socio-economic status (SES), and religious coping, among Muslim women students at the Women Centre for Continuing Education (WCCE), in Sokoto, Northern Nigeria. A total number of 269 Muslim women students were selected to participate in this study using purposive random sampling. Instruments namely Orientation to Happiness Scale (OHS), Cultural Questionnaire for Women, (CQW), Socio-Economic Status Scale (SESS), Islamic Religious Coping Scale (RCOPE) were used for data collection. The total Cronbach’s alpha Coefficiency was 0.937, which was found to be reliable.  The results were analysed using Partial Least Squares-Structural Equation Modelling (PLS-SEM).  The measurement model was evaluated using items loading of average variance extracted (AVE) and composite reliability (CR). The findings of this study showed that the direct relationship of culture, socio-economic status and religious coping towards happiness were significant. As a conclusion, this study provides useful information for counsellors who can assist their clients in improving and maintaining their positive religious coping practices, as well as their ability to encounter positive feelings, engage in Islamic practices, have a meaningful life, and cope with stressors. Future research on happiness in other Northern states of Nigeria is recommended.
Molecular Detection of Microsporum Canis Infection in Cats in Baghdad Governorate
Authors: Bidewy Marwah Abdul Hassan , Hasso Saleem Amin
Published: October 2024

Microsporum canis is a keratinized skin fungus that causes diseases in all animals, especially in cats. It is able to infected human causes Tinea corporis and Tinea capitis. In this study,the aim was toward detection and confirmation of Microsporum canis infection in cats  in Baghdad governorate using polymerase chain reaction (PCR).The diagnosis depend on sequencing of the PCR products obtained by using a universal primer to amplification of the primer DppV which was 895 bp.A total of two hundred and eighty three hair and skin scraping samples were collected from infected cats with and without skin lesions. Preliminarily examined of samples with 10% KOH preparation, and cultured for fungal identification . For the culture; Saboruad dextrose agar was used . Culture results showed that four isolates were positive for M. canis , the best growth of these isolates was confirmed by PCR and DPPV gene then sequencing of this gene. PCR technique showed that one isolate from the total of 283 isolates were assured for the DPPV gene and yielded a band at 895 bp, this finding is regarded as distinctive for the genus Microsporum canis ,which was dumped in the GenBank nucleotide sequence database under accession number OR126262. Results sequencing of this gene in Iraq revealed compatibility with global results in USA and Belgium.
The Sensitivity and Specificity of Susceptibility Weighted Imaging Phase (Swip) in Detecting Intracranial Large Artery Calcium Stenosis Compared to Cone Beam CT
Authors: Zyoud Tawfiq Yousef Tawfiq , Kamaruddin Muhammad Hasif Bin , Hamid Suzana Ab , Md Noh Mohamad Syafeeq Faeez Bin , Ahmad Umar , Kabeer Abubakar , Rashid Saiful Nizam Abdul , Suppiah Subapriya , Mahmud Rozi , Rahim Ezamin Abdul
Published: October 2024

Introduction: Intracranial calcifications are common and often associated with advanced stages of atherosclerosis. Studies estimating the prevalence of intracranial calcifications using other imaging modalities are common, however, studies comparing the diagnostic accuracies of cone-beam computed tomography (CBCT) and susceptibility-weighted imaging (SWI) and generated scoring systems for SWI are not well established. Aims: The objectives of the present study are to identify locations of intracranial calcifications; estimate the sensitivity and specificity rates for each intracranial vessel and each modality; estimate the sensitivity and specificity rates for diagnosing each grade of stenosis for each modality; and generate cutoff value for predicting each grade of intracranial stenosis and for each modality; as well as to develop a scoring system for estimating intracranial stenosis using SWI. Material and Methods: The study employs a prospective cross-sectional study design to collect brain data from 146 stroke patients who had initially undergone CBCT and SWI examinations. Data were collected using pro forma from January 2021 to December 2022 at Hospital Pengajar Universiti Putra Malaysia. Results: The results show an estimated prevalence of intracranial calcification of 87.7% and 92.5% for CBCT and SWI respectively. Regarding intracranial calcium grades, the prevalence of minimum – mild, moderate, and severe grade stenosis were 18.5%, 58,9%, and 10.3% respectively for CBCT and 2.7%, 33.8%, and 57.5% for SWI. Further, the results revealed that CBCT attained a sensitivity of 100% for the anterior cerebral artery, 71% for the middle cerebral artery, and 100% for the vertebral artery as well as a specificity of 90%, 80%, and 42% for the anterior cerebral artery, middle cerebral artery, and vertebral artery respectively. However, with the SWI modality, basilar, vertebral, and middle cerebral arteries reached a sensitivity of 90%, 63%, and 87% and a specificity of 82%, 95%, and 59%. Conclusion: In conclusion, both CBCT and SWI demonstrate reliable means of detecting intracranial calcifications and vessel stenosis with SWI outperforming CBCT.
Model of Life Skills Based Drug Education on Knowledge About Drug Use, Self-Esteem, and Assertiveness Skills Among Indonesian Adolescents at Risk
Authors: Trihadi Dayat , M.A Sri Hartini , Noer’aini I’ien
Published: October 2024

Introduction: Adolescent drug abuse is a global concern, affecting young people's freedom and development. In Indonesia, illicit drug abuse has increased, causing severe social, political, and economic problems. Methods: A quasi-experimental design was used in this study to test the effects of life skills-based drug education on knowledge about drug use, self-esteem, and assertiveness skills. Teen participants were divided into experimental and control groups. Results: Language and Social Education (LSE) significantly influences students’ understanding of drug use and assertiveness training while also somewhat raising their self-esteem. On the other hand, it had no appreciable impact on Indonesia’s at-risk students in Semarang, Central Java Province. The report stressed that the first stages in an LSE program intended to stop teenage drug use are for students to gain knowledge and skills. To attain the best results in drug use prevention, more routes must be created. Conclusions: gaining information and skills improves attitudes and values, which in turn encourages drug use in a good way. Consequently, to support Indonesian students who are at risk of drug use in staying drug-free and developing into healthy, contributing members of society, these programs require further study and improvement.
Observations In Police Records And Their Prospection To Tutelas De Derecho In Criminal Proceedings
Authors: Hilter Suarez Peña,
Published: October 2024

The main objective of the research was to analyze the normative limits to establish party observations in police records as part of the exercise of the right to defense and its prospection to protect rights in criminal proceedings. The results of the investigation showed that Peru continues to suffer the effects of abusive police activity that generates irreparable damage to the human essence of the people intervened in an abusive manner or without respect for their fundamental rights because they develop within them a criterion of abusiveness and disproportionality in the treatment by the intervening police officers.  For this reason, the investigation establishes the importance of the right to write the observations of the detainee or his defense in the police records in order to denounce on the spot the abuses or arbitrariness committed during the proceedings, since, in most cases, there is a nonsense in the exercise of the function and it is established that the detainee refused to sign the report. It was concluded that there are problems related to arbitrariness in the exercise of police functions that are not reported in a timely manner by the victims, generating mistrust against the authorities and public institutions.
Production and Optimization of Xylanase Enzyme from Bacillus cereus by Submerged Fermentation Method
Authors: Alhussien Ashraf Abd , Chelab Rahman Laibi
Published: October 2024

Three strains of Bacillus cereus were isolated from soil samples in this study in an effort to enhance the circumstances for the production of xylanase by the bacteria. The bacteria released extracellular xylanase throughout the submerged fermentation process. In a 250 ml conical flask, the whole fermentation process was conducted at 150 rpm stirring speed. The highest amount of xylanase synthesis was demonstrated by the isolated strains at 45°C, 48 hours of incubation, pH 5, 1.5% oat splet xylan base concentration, lactose carbon source, and beef extract source.
The Model of Nursing Administration and Quality of Working Life Management of Nurses after COVID-19 Pandemics, in Thailand
Authors: Nawasanan Wongprasit
Published: October 2024

The research results showed that 1) Conditions and guidelines the nursing administration and quality of working life in during and after the pandemics COVID-19 were explored and found that executives understood their personnel and emphasized that relevant personnel must perform their duties according to the measures to prevent the spread of COVID-19. Problems found included insufficient personnel for the work and overlapping roles. Factors that supported personnel to manage their work quality after the COVID-19 outbreak included teamwork, participation in planning and solving work safety issues, having time for work and family, and job satisfaction. The guidelines for operations after the COVID-19 outbreak should include changes to the work system, building morale, participation, teamwork, and job satisfaction. Good time management could affect the quality of life of nurses. 2) In the study of measurement model, it was found that all sub-component latent variables were suitable as the observed variables of each main component, and all main components were suitable as the observed variables of the nursing administration model and the management of working life quality of nurses after the COVID-19 outbreak. When checking the consistency of the measurement model, the measurement model was consistent with the empirical data, thus confirming the development of the nursing administration model and the management of working life quality of nurses after the COVID-19 outbreak in Thailand, by the linear structural component analysis method. 3) the model of nursing administration and quality of working life management of nurses after the COVID-19 pandemic in Thailand or SWAP FECT MODEL; it was found that all experts confirmed that the model was a model with practical steps, consisting of 2 main components, 10 sub-components, and 66 indicators. The main components of nursing administration in the VUCA model had 3 sub-components: transparency, empowerment of subordinates, and collaboration. The main components of management of working life quality had 7 sub-components: agency support, work safety, work participation, work satisfaction, well-being, self-development, and free time management. There were 3 steps of good management: 1. Inputs 2. Processes and 3. Outputs.
Comparative Effects of Fedratinib and Upadacitinib on Renal Ischemia-Reperfusion Injury in Rat Models
Authors: Hussein Furqan Hashim , Mosawi Najah R. Al
Published: October 2024

Renal ischemia-reperfusion injury (RIRI) is a severe condition that frequently occurs following kidney transplantation or surgical procedures affecting renal blood flow. Inflammatory responses, oxidative stress, and apoptotic pathways significantly contribute to RIRI. This study aimed to compare the renoprotective effects of Fedratinib, a JAK2 inhibitor, and Upadacitinib, a JAK1 inhibitor, in rat models of RIRI. Both inhibitors were administered one hour prior to ischemia induction, and the effects on renal function, inflammation, and cell death pathways were assessed. The findings revealed that both Fedratinib and Upadacitinib significantly reduced serum creatinine and urea levels, inflammatory cytokines (TNF-α, IL-6), and markers of apoptosis (BCL2/BAX) by suppressing the JAK/STAT signaling pathways. Histopathological analysis showed substantial reduction in renal tissue damage in the treated groups compared to controls. The study concludes that JAK inhibition by either drug provides significant renoprotection in RIRI, though with some differences in the degree of pathway inhibition and clinical implications.
Prevalence and Association of Obesity, Depression, and Psychological Stress Among the Population of Saudi Arabia
Authors: Alreshidi Nahlah Fahad , Alenzi Hailah , Alrashidi Rasha , Aljaloud Luluh
Published: October 2024

Background: Obesity, stress, and depression are widespread global issues that have a significant impact on people's personal and public health. Studies reveal that the incidence of anxiety and sadness is significantly higher in obese people. Purpose: This study aimed to find ‏the prevalence and association of obesity, depression, and psychological stress among the population of Saudi Arabia. Methods: A cross-sectional study involving the society in general Saudi Arabian population that was conducted. A self-administered questionnaire is disseminated to the populace through an online platform. Results: About 72.1 percent of the 1075 respondents were female, while 52.6 percent were between the ages of 21 and 30. The proportion of obese individuals amounted to 20.6%. In contrast to melancholy (39.4%), psychological tension was present at a prevalence of 77.8%.  A statistically significant correlation was observed between stress and depression; however, no such correlation was found between depression and overweight or obesity. Conclusion: Our study indicates that, contrary to what the literature suggests, numerous stressors rather than melancholy may be the cause of obesity rather than a risk factor for the condition. Further investigation is required to ascertain the correlation between psychological tension, obesity, and melancholy.
Saudi Bachelor Nursing Students' Perceptions of Academic Advising: Descriptive Quantitative Study
Authors: Jumah Jawaher Abdullah Bin , Nouh Nazirah Omar , Faltah Reemah , Alonazi Maha
Published: October 2024

Academic advising is identified as a progression to assist the students in determining their competencies which would guide them to find and develop their academic identity and ensure which study program and major would fit their capabilities within the facilitated opportunities. Aim This descriptive quantitative research was to analyze the relationship between undergraduate students and their academic advisors, evaluate the obstacles of the academic advising process from their' perception, and assess the resolutions of the academic advising. Methods: This descriptive quantitative study was conducted on a convenience sample of 200 nursing students in different courses and levels in the College of Nursing at King Saud University using demographically collected data. ResultsThere was a significant indication of a relationship between social demographic data and student perception of academic advising. Conclusions Implementing academic advisory could improve the students' achievements and overcome learning obstacles that could affect nursing students' learning outcomes. Suitable supervision from academic affairs strengthens their positions.