bluuebunny/crossref_metadata_2025 huggingface dataset:
Lipoatrofia semicircular en trabajadores de oficinas públicas
Authors: Borin-Bertuzzi Mario , Alonso-Iglesias Oscar , Borin-Arámbulo Mario Andrés
Published: March 2022

Introducción: La lipoatrofia semicircular (LS) es un trastorno benigno del tejido subcutáneo, de causa no bien conocida, caracterizada por depresiones semicirculares en la cara anterolateral de los muslos y menos frecuentemente en abdomen o brazos. 

Método: Estudio observacional, prospectivo, longitudinal, en 449 trabajadores de oficina, localizados en varios edificios de la ciudad de Castelldefels, Provincia de Barcelona, España, entre julio 2018 y abril 2021 a los que se les realizó identificación, mediciones, fotografía y controles periódicos de la LS. Los resultados fueron analizados mediante el programa Instat Graphpad y se aplicó la prueba de Fischer para determinar la significancia estadística.

Resultados: Se diagnosticaron 74 casos de LS en un total de 449 trabajadores. Prevalencia: 16,48%. De los 74 casos identificados, 71 eran mujeres (95,9%). El promedio de edad fue 49,18 años (27-64). La mayoría de las lesiones se localizaron en los muslos en forma bilateral. Las lesiones de LS no desaparecieron en el 66,6% de los casos, mientras que en un 33,3% si lo hicieron. El teletrabajo y el índice de masa corporal no resultaron factores significativos en la desaparición de las lesiones.

Conclusiones: La LS es una alteración infrecuente del tejido subcutáneo, en la que influyen una serie de factores que van desde el medio laboral, la susceptibilidad individual y el sexo femenino. La LS toma un tiempo muy variable para revertir, suele ser un proceso lento cuya duración se mide en años más que en meses. Ni el teletrabajo, ni el índice de masa corporal, tuvieron una relación estadísticamente significativa en la desaparición de las lesiones en esta serie.
Simulating System for Technical Characteristic Analysis in Power Generation by Wind Turbine Generator
Authors: Srisongkram Warunee , Phanthuna Nattapong
Published: March 2022

This paper describes the design of the controlling and monitoring system for electricity quality from wind turbine. The 4-RMUT (Rajamangala University of Technology) network joined in this research in order to apply for educational learning as well. This research proposes two objectives as follows: firstly, inventing the prototype of wind turbine for generating electricity including analyses to increase and monitor its efficiency; finally, demonstrating the prototype with our students in order to increase more understanding in a class than ever. The conclusion and developing of this research were also transferred the technical knowledge to the electrical engineering student by discussion in the class. Furthermore, the technical discussion in the class was also improved the teaching efficiency and given more vision to the engineering student as well.
Analysing the Impact of the Monetary Policy Dynamics on Financial Imbalances- A Model Approach
Authors: Bakhit Wael
Published: March 2022

This paper employs a quarterly time series to determine the timing of structural breaks for interest rates in USA over the last 60 years. The Chow test is used for investigating the non-stationary, where the date of the potential break is assumed to be known. Moreover, an empirically examination of the financial sector to check if it is positively related to deviations from an assumed interest rate as given in a standard Taylor rule. The empirical analysis is strengthened by analysing the rule from a historical perspective and look at the effect of setting the interest rate by the central bank on financial imbalances. The empirical evidence indicates that deviation in monetary policy has a potential causal factor in the build up of financial imbalances and the subsequent crisis where macro prudential intervention could have beneficial effect. Thus, my findings tend to support the view which states that the probable existence of central banks has been one source of global financial crisis since the past decade.
The Issues of the Improvement of the Methodology for the Assessment of Reforms
Authors: Davoyan Samson , Davoyan Ashot
Published: March 2022

The purpose of this article is to suggest a new methodology that will give us an opportunity to create an Integral Index of Reforms (IIR) that will include seven indexes: KOF Index of Globalization, The Democracy Index, The Corruption Perception, The Human Development, Doing Business, The Global Competitiveness Index and The Index of Economic Freedom. From both scientific and empiric perspective it is supposed that the quantitive assessment of various reforms implemented in different countries based on presented indicators of seven indexes despite the new methodology that we suggest give us the opportunity to include much more indexes.
Examining Learning Outcomes of Inquiry-Oriented Instruction in Introductory Linear Algebra Classes
Authors: Haider Muhammad Qadeer , Andrews-Larson Christine
Published: March 2022

This study evaluates the effectiveness of inquiry-oriented instruction in introductory linear algebra classes by comparing the performance of students who learned introductory linear algebra concepts in inquiry-oriented settings (TIMES students) with the students who attended other linear algebra classes (Non-TIMES students). We used the assessment data from 461 students (271 TIMES and 190 Non-TIMES students) which were collected from 19 linear algebra classes at 15 institutes across the country. The linear algebra assessment was given as a post-test to all students, and TIMES students performed significantly better than Non-TIMES students. Overall, the difference in the performance of both groups was statistically significant in the entire assessment, procedural subscale, and conceptual scale of the assessment. In a pair-wise comparison of TIMES and Non-TIMES classes, only those TIMES classes performed significantly better than the Non-TIMES classes on the linear algebra assessment where instructors have more experience with inquiry-oriented teaching.
The Degree of Native Language Teachers’ Consideration of Persuasive Writing Skills in Teaching Expression
Authors: ALhawamdeh Haifa , KhairEddeen Lamia
Published: March 2022

This study aimed to examine the degree of Arabic language teachers’ consideration of persuasive writing skills in teaching expression and their differences according to the variables of gender, academic qualifications, and years of experience. To achieve the objectives of the study, the descriptive approach was applied in the form of the school survey method. The study sample consisted of 239 male and female Arabic language teachers in public schools of Najran region in the Kingdom of Saudi Arabia. They constituted 42.7% of the study population. To collect the data, the study used a questionnaire consisting of 21 items after verifying its validity and reliability in the Saudi context. The results showed that the degree to which the Arabic language teachers consider the persuasive writing skills in teaching expression in all domains of the study instrument and the total score ranked moderate. Also, the results revealed that there were statistically significant differences in the degree of Arabic language teachers’ consideration of persuasive writing skills in teaching expression in all domains of the study instrument and the total score due to gender variables in favor of females, academic qualifications in favor of graduate studies, and years of experience in favor of ten years or more. The study recommends the Ministry of Education should work on developing the practices of Arabic language teachers for persuasive writing skills in teaching expression by providing appropriate training programs.
The Effects of Learning Strategies on Senior High School Students' Motivation and Learning Outcomes of Overhead Passing in Volleyball
Authors: Akhmad Imran , Suharjo Suharjo , Hariadi Hariadi , Dewi Rahma , Supriadi Amir
Published: March 2022

This research objective was to determine the effects of Learning Strategies on Motivation and Learning Outcomes of Overhead Passing in Volleyball. The research sample consisted of 40 eleventh-grade senior high school students using a treatment by level 2x2 research design with the Tukey’s test at Qh level = 28.99 and Qt level = 3.79. The results significantly affected overhead passing learning outcomes in volleyball games between contextual teaching-learning (CTL) and expository learning strategies. The research results obtained FhFt, namely 47.80 4.06. Therefore, the overall conclusion reported an interaction between learning strategies and motivation on learning overhead passing in volleyball games. The Tukey’s test in groups A1B1 and A2B1 resulted in Qh= 17.42 and Qt=2.95. Based on these results, it can be concluded that the results of learning overhead passing in volleyball games on highly motivated students who were taught using the contextual teaching-learning strategy (CTL) were better than those taught using expository learning strategy. The Qh= 2.16 and the Qt = 2.95, meaning that the results of learning overhead passing in volleyball games of low motivated students who were taught using the contextual teaching-learning strategy (CTL) were not better than those taught using the expository learning strategies.
The Effect of Using Concrete-Representational-Abstract Sequence in Teaching the Perimeter of Geometric Shapes for Students with Learning Disabilities
Authors: AL-salahat Mohammad Mousa Salem
Published: March 2022

Geometry is one of the basic areas of school mathematics education, and it is important for elementary students. However, students with mathematics learning disabilities (MLD) struggle with geometry learning. Research has demonstrated that concrete-representational-abstract (CRA) teaching is an effective practice for students with learning disabilities (LD) and other disabilities. The study aimed to investigate whether the CRA sequence can support students’ understanding of calculating the perimeter of geometric shapes and solving mathematical word problems of the perimeter in Najran city in the Kingdom of Saudi Arabia. The study used the quasi-experimental research design for one treatment group of a pre-posttest. First, the perimeter test of geometric shapes, whose validity and reliability was verified, was used, and then the CRA sequence was applied to eight students in the fourth and fifth grades with LD in mathematics. The results showed that the CRA sequence improved the students’ efficiency in calculating the perimeter of geometric shapes and solving mathematical word problems on the perimeter. Also, the students maintained the learned skills three weeks post the interventional period.
Rüzgâr Türbinlerinde Kullanılan Farklı Kanat Profillerinin Sayısal Olarak İncelenmesi
Authors: TARHAN Cevahir , ÇİL Mehmet Ali
Published: March 2022

Rüzgâr türbinlerinden elde edilen enerji miktarı her geçen gün artmaktadır. Rüzgâr türbinlerinin güç çıkışlarını etkileyen faktörlerden birisi de kanat profilleridir. Bu çalışmada rüzgâr türbinlerinde kullanılan farklı (NACA 0009, NACA 2415, NACA 4415, NACA 4424, NACA 6412, NACA 6415, NACA 24112, FX 63-137, GOE 795, NREL’s S824, SD 5060, SG6040) kanat profillerinin Qblade yazılımı kullanılarak simülasyonları oluşturulup sayısal analizleri yapılmış ve aerodinamik performansları incelenmiştir. Sayısal analizler 0°- 20° arası hücum açılarında ve 5x104, 2x105 1x106 Reynolds sayılarında gerçekleştirilmiştir. En yüksek aerodinamik verimliliğe sahip kanat profilleri NACA 6412, NACA 6415 ve NACA 4415 olarak belirlenmiş ve bu kanat profillerinden üç kanatlı rüzgâr türbini oluşturulup elde edilen güç çıkışları ve performans değerleri bulunmuştur. Bu kanat profilleri için uç-hız oranı 6.5 ila 7.8 aralığında maksimum verim alınmıştır. Sonuç olarak rüzgâr türbinlerinde NACA 6412, NACA 6415 ve NACA 4415 kanat profilleri kullanılarak türbinden alınacak verim maksimum seviyede olacaktır. Bu çalışmada, literatürde mevcut olmayan AG37, AH 80-140 NACA 8824 ve RG-12 kanat profilleri literatüre katkı sağlamak amacıyla analiz edilmiştir.
Crashworthiness Performance of Al6061 Tubes with Stiffened Quatrefoil Sections under Axial and Oblique Impact Conditions
Authors: KOCABAŞ İbrahim , YILMAZ Haluk
Published: March 2022

This study presents the crashworthiness performance of Al6061 tubes with stiffened quatrefoil sections under axial and oblique impact conditions. Influences of different types of stiffeners through the depth of tubes in the design of a quatrefoil sectional crash absorber structure are investigated, numerically. Four types of stiffener patterns are considered under oblique impact angles of 0º, 10º, 20º, and 30º measured from the horizontal axis. Force-displacement characteristics, deformation patterns, and crashworthiness indexes of the tested tubes are given to decide optimal crash absorber configuration. The numerical tube models are placed between two rigid plates and an axial impact speed of 1m/s is considered in the numerical study. Al6061 series aluminum alloy is used as a tube material with a multi-linear material model assuming strain-rate independent properties. It is found that the crashworthiness performance is very sensitive to impact angle and Q-S-4 type stiffeners can be proposed for a better tube design.
Properties and Distribution of Seed Banks in a Black Locust (Robinia pseudoacacia) Plantation in Central China
Authors: Zhang K.Q. , Yang X.C. , Shen Z. , Ma L.Y. , Duan J. , Li Y.
Published: March 2022

We aimed to compare the properties of seed banks in different types of Robinia pseudoacacia stands and different substratum layers. We established four Black locust plots (each 50 × 50 m) that included two second-generation stands and two third-generation stands. Spatial coordinates, diameter at breast height, and the heights of all trees were measured in the four plots. In each plot, we set a total of 259 points using the regular grid design method. At these points, we sampled the seed banks in the litter and soil (0-5 cm) layers. The coordinates of the 259 points were recorded. After the samples had been collected and screened, a germination trial was performed using the collected seeds from the different layers and stands. We used variogram and kriging interpolation geostatistical methods to analyze the distribution of the seed banks. A kernel density estimation map was generated to examine the relationship between the seed bank and trees in each stand. The results showed that seed bank density was high in the four stands (4005-7325 seeds.m-2), and was higher in the third-generation stands (6085 and 7325 seeds.m-2) than in the second-generation stands (4005 and 5659 seeds.m-2). The seed bank density in the litter layer (3225 seeds.m-2) exceeded that in the soil layer (2164 seeds.m-2). The spatial pattern of the seed banks varied among different stands and was positively correlated with the distribution of trees in each stand. Furthermore, we found that spatial autocorrelation in the seed banks occurred at a variety of scales. Seeds in the litter layer were significantly more active than those in the soil layer; the germination rate varied from 6.67% to 28.89%. The findings of this study suggest that the Robinia pseudoacacia plantation in the Luoning area may exhibit potential for regeneration from seeds, and this will be the focus of our future studies.
Insight into Effects of Initial Moisture Content on the Heat-Up of Sewage Sludge Composting During Mesophilic Phase
Authors: Li Yu , Su Yuran , Hu Bin , Ma Chuang
Published: March 2022

The effects of initial moisture content (55%, 60% and 65%) on the heat-up of sewage sludge (SS) composting during the mesophilic phase were investigated. Monitoring results showed that low moisture content (55%) increased the heating rate, high initial moisture content (60% and 65%) significantly improved the activities of cellulase and peroxidase during the mesophilic phase. Furthermore, although high moisture content improved the diversity of bacteria during composting, there were no significant differences in the microbial structure during the process of succession. So, rather than inhibiting the activity of the bacterial population, the negative effect of high moisture content (60 and 65 per cent) on composting temperature heat up was attributable to the difficulty of heating produced by the specific heat capacity of water. The correlation index between initial moisture content and microorganisms was relatively low, while the temperature was the largest environmental factor affecting the bacterial community. This conclusion provided a hint to make an association between initial moisture content and composting temperature-rising stage.
El Puerto de Santa María en la Baja Edad Media: aspectos económicos y sociales
Authors: Lubián Olmedo Juan Carlos
Published: March 2022

Este artículo tiene como finalidad mostrar las características de la sociedad y los aspectos económicos de El Puerto de Santa María durante el siglo XV. En el artículo se exponen los resultados de un análisis de los oficios de la época en la villa y de las relaciones comerciales entre las villas de El Puerto y Jerez. Además, se muestran datos sobre el contexto social y político de la villa en el siglo XV. El estudio se basa en una revisión bibliográfica y en la consulta de protocolos notariales. Tras la investigación, se constata la relevancia de El Puerto como villa y su encuadre en el contexto social y económico de la Castilla del siglo XV.
The economic contribution factors of stokvels in the local economy of eThekwini Municipality
Authors: Bophela Mduduzi Justice Kennedy , Khumalo Njabulo
Published: March 2022

The absence marginalisation and lack of recognition of the role of stokvels in the official economic plans and policies of the municipality was therefore the problem that this paper sought to explore. Simple random method was adopted on 395 stokvel group’s members who were administered with a questionnaire and the purposive sampling method on 6 MC members of eThekwini Municipality that participated in the interviews. The qualitative data was analysed using N-VIVO (version 11.0). The quantitative data was analysed using inferential and descriptive statistics. Money saving & investment, job creation and promoting business opportunities are the most prevalent of the economic contribution factors of stokvels. EM needs to pioneer the amendment of the current policy inclusive of the informal economy.
Pioneers of African Initiated Churches (AIC) as actors of development: A case of Paulos Matsea Mureri of the United African Apostolic Church (UAAC) and community development
Authors: Ranwedzi Ndivhuwo Emmanuel , Nesamvuni Azwihangwisi E. , Van Niekerk Johan
Published: March 2022

The role of Africans, those associated with African Initiated Churches (AIC), in spreading the gospel, which contributed to human development, has not been fully recognized even in the current political dispensation in South Africa. Most literature has given specific focus to the western missionaries and their approach to the gospel has been widely accepted as the way of the gospel. The establishment of AICs such as the United African Apostolic Church (UAAC) initiated by Matsea Paulos Mureri display an unignorable phenomenon in terms of the contribution he made as a gospel crusader and actor of development within and outside his community. Through the seed that Matsea Paulos Mureri planted, the church has grown to over a million members internationally. He comes from a generation that experienced the emergence of the Pentecostal movements which shaped the African Initiated Pentecostal Churches (AIPC) and they have survived a century of various marginalization. Unlike Evangelical and Pentecostal movements, their contribution to human development has been recognized through their contribution to education and health sectors. However, human development concept is much broader. In terms of Paulos story, important questions are asked in reflection of some of the challenges which continue to confront the AICs particularly in the area of succession. Like most of the AICs, the UAAC has not been spared from disputes and splits which have confronted most AICs since their inception. Some of the imperative questions asked is whether the leadership conflicts and disputes which surround the AIC’s are real leadership disputes or are polygamous conflicts which are disguised under church leadership battles. Secondly, a question is raised about the contestation of two opposing cultures i.e. the African unwritten law versus the western written law on the rights and privileges of adopted children in terms of succession. Although the two question may sum up the kind of legacy that Matsea Paulos Mureri left in his quest to be a gospel distributor, it does not erode his contribution to human development.
The Impacts of FDI, ODA, and LS on Gross Domestic Product in Cambodia: A Comparative Analysis
Authors: Chet Vathanak
Published: March 2022

The study focus mainly on the impact of ODA, FDI, and LS on the GDP growth of Cambodia from 1995 to 2020 using the combined data generated from Macrotrends LLC (2021); Trading Economics (2021); World Bank Group (2021a; 2021b; 2021c & Cambodia Public Debt Statistical Bulletin (2015; 2016; 2017; 2018; 2019; 2020; 2021) and the Eviews 10 was used as a tool to analyze the data by applying the multivariate regression with ordinary least squares method. The result confirmed that FDI and LS are significant and positively contributed to the GDP growth of Cambodia with almost 100% confident interval or probability of 0.02%, and the ODA was evidently insignificant and also negatively impacted on the economic growth of Cambodia. The researcher also suggested for further researches in order to clarify the lapses of this study.
Actors and key resources in facilitating the transition of students from one school cycle to another
Authors: Medeanu Camelia , Moron Nicoleta
Published: March 2022

Currently, many researchers are focusing on the educational environment to assess the impact of the pandemic on the educational success of pre-university or even university students. Most of the hypotheses are related to the influence of the alternative teaching methods used during the pandemic on the school results, on the socio-emotional situation and on the resources available to students and teachers to respond better to the new format of teaching and assessment in times of crisis. In this context, it is highly unlikely that the results of such studies will be interpreted in light of the challenges already existing in a pre-pandemic education system. The paper we propose brings into question exactly this general context, offering researchers a benchmark in their analyzes regarding the impact of the pandemic on the Romanian educational environment. We base our approach on the results of a qualitative research undertaken in educational institutions in the North-East Region of Romania. The research included interviewing 60 teachers, using the in-depth interview to capture the difficulties that students and teachers face in successfully ensuring the school transition. The results of our study highlight aspects related to key actors that can support the successful implementation of the school transition, existing barriers and resources needed to facilitate the school transition.
Increasing the relevance of records on motor development through specialized software
Authors: Tomescu Gabriela , Stănescu Monica-Iulia , Aivaz Kamer-Ainur
Published: March 2022

Leisure motor activities are not a constant in the educational program of institutionalized children. In the context of several specialized studies suggesting that those who are raised in foster care have a slower or poorer physical development compared to those who grow up with their family, we have conducted a comparative study between a group of institutionalized children and a group of dancers, through which the level of motor development of the two categories could be established objectively. Given that dancesport is not yet used as a means of development and social integration for the children in orphanages, the purpose of this subject is to highlight the contribution of dancing to the psychomotor development of preadolescents. The results of the initial testing with the Optojump device indicate the effectiveness of dancesport in children from families. Thus, an intervention model was developed based on contents of dancesport, in order to stimulate the motor skills of institutionalized children. At the end of the research, significant differences were identified between the initial phase results and the final testing results.
The Present and Future Prospects of Japanese FDI in Hungary
Authors: Goreczky Péter
Published: March 2022

Traditionally, the cornerstones of Hungary’s competitiveness in FDI attraction have been the favourable geographic location and the availability of a qualified and cost-effective labour pool. Western countries are still far the most important sources of the FDI stock in Hungary, however Japan is the second largest investor among Asian nations. Most of the Japanese FDI has been concentrated in the automotive sector and has targeted Western, Central and Northeast Hungary. Some Japanese investors have already started to locate high-end manufacturing technologies to Hungary which was in line with the country’s goal to be at the forefront of Industry 4.0. The main challenge on the Hungarian side is whether the country can ensure the necessary pool of talents and skilled labour to maintain its attractiveness and to move up in the value chain.
An Optimized Machine Learing Framework For Extracting Suicide Factors Using K-Means++ Clustering
Authors: S R Naren , P C Thirumal , D Sudharson
Published: March 2022

Suicide has emerged as one of the serious problems which should be eradicated from the society. People with suicidal thoughts restrict themselves by not expressing thoughts to the people around them. Studies have shown that people show more interest in expressing their thoughts over social media platforms. So, research has been conducted to identify people with suicidal ideation by analyzing the posts which they posted in social media platforms. Certain studies mined out new factors which influenced people to commit suicide, but those factors had certain drawbacks in it. This paper mainly focuses on overcoming those drawbacks in the factors. A new modified approach for extracting those risk factors is introduced as it can be used for future works related to suicidal ideation detection tasks. Statistical methods were imposed on the data to mine out the underlying characteristics of the features. K-Means++ clustering algorithm was implemented to extract the modified features. The modified features were given as an input for a testing classifier, and it attained an accuracy of 75.13%.
JOHN RUSKIN VE YEDİ YOL GÖSTERİCİ IŞIKTAN “BELLEK”
Authors: ÜNAL Güneş
Published: March 2022

John Ruskin, günümüzde anti-restorasyon ve konservasyon kavramlarıyla özdeşleşmiş, romantik olarak nitelendirilen bakış açısıyla da yaşadığı dönemden itibaren çok farklı kesimden övgü ve eleştiri toplamıştır. Ruskin’in eserlerini ve düşünce biçimini salt okuma ile anlamak mümkün değildir. İçine doğduğu aile ve çevre dahil, hayatındaki diğer her bir olay ve detay Ruskin’in bakış açısını, buna paralel olarak da eserlerini etkilemiştir. Eserleri sadece mimarlık ve koruma alanında değil, toplumsal konulardan mitoloji ve botaniğe kadar uzanan geniş yelpazesi ile 19. yüzyılın kültürel değişimine ışık tutmaktadır. Bu bağlamda Ruskin’in eserlerinden “Mimarlığın Yedi Yol Gösterici Işığı” ele alınmış ve altıncı ışık olan “bellek”, konservasyon çatısı alında irdelenmiştir. Ardında bıraktığı değerli düşünce filizlerinin bugüne nasıl evrildiği ise ayrıca önem taşımaktadır.

Summary

In today’s world, John Ruskin is known with the notions anti-restoration and conservation. Also, with his point of view characterized as romantic, starting from his era to today, he had received numerous compliments and criticisms, people from different walk of life. It is not possible to understand Ruskin’s work and way of thinking only by reading his publications. Every event and detail in his life including the environment that he had born in and his family, are effective on Ruskin’s point of view and parallelly his works. His works shed light on the cultural change of the 19th century, not only in the field of architecture and conservation but also from the wide range of social subjects to mythology and botany. In this context, one of the Ruskin’s most famous works, “The Seven Lamps of Architecture” was held and “memory” which is the sixth lamp, was examined within the framework of conservation. It is also important to see how his valuable thinking that he left behind has evolved to the present.
O ESTUDO DA PATOGÊNESE E DA HISTOPATOLOGIA DO RETINOBLASTOMA NO CENÁRIO DE PESQUISA CIENTÍFICA BRASILEIRA: UMA REVISÃO DE LITERATURA
Authors: Matsumoto Caroline Mary , Pieri Bruna Cristina Mattos de , Gonçalves Gabrielle , Feitosa Kawanna Izabella Buzzo , Basso Sophia Oliveira
Published: March 2022

Introdução: O retinoblastoma (RB) é uma neoplasia maligna intraocular da infância, sendo o quarto câncer pediátrico mais frequente no Brasil. Quando analisados dados prognósticos, há distinção entre países desenvolvidos e subdesenvolvidos devido ao tempo do diagnóstico. Se identificado tardiamente, o RB conduz à cegueira, torna-se extraocular e até fatal se tiver alcance do sistema nervoso central. Objetivos: Realizar um estudo sobre a patogênese e a histopatologia do RB através do conteúdo existente no cenário de pesquisa acadêmica brasileira. Material e métodos: Houve a análise da literatura científica brasileira sobre a patogênese e a histopatologia do RB, publicados entre 2000 a 2021 e presentes nas bases de dados SciELO, PubMed e BDTD. Utilizou-se os seguintes descritores em português: retinoblastoma, patogênese do retinoblastoma e histopatologia do retinoblastoma. Resultados: Mesmo com uma incidência considerável no país, há escassez de estudos. Nos encontrados, nota-se que o RB é de origem genética autossômica recessiva e diferencia-se em espontâneo (duas mutações necessárias) ou hereditário (uma já herdada). O gene do RB sintetiza uma proteína supressora de tumores. A aparição clínica da esporádica é unilateral e com um único tumor, enquanto a germinativa apresenta bilateralidade, multiplicidade de tumores e surgimento precoce. Em análise microscópica, observa-se células neuroblásticas de núcleo grande e basofílico. Há três arranjos: rosetas de Homer-Wright, de Flexner-Wintersteiner e “fleuretes”. As células das rosetas organizam-se radialmente, o primeiro em torno das fibrilas e o segundo em um lúmen vazio. As de Flexner-Wintersteiner e os “fleuretes” - de núcleo menor - são a especialização em fotorreceptores. Através destas estruturas, apura-se o grau de diferenciação do tumor e de sua periculosidade. Quando 80% do câncer possui rosetas, é bem diferenciado. Outro aspecto histopatológico importante é a identificação de células cancerosas no nervo óptico, alertando à metástase. Conclusão: Há grande necessidade de novos estudos sobre a patogênese e histopatologia do RB considerando sua incidência e a escassez no que diz respeito à pesquisa brasileira. Esses são necessários para um melhor conhecimento sobre o RB e sua identificação precoce, tornando essa revisão relevante para direcionamento de futuras análises sobre o tema.
ANÁLISE HISTOPATOLÓGICA DA TOXICIDADE AGUDA DA CANNABIS SATIVA
Authors: Oliveira Anthonielle Ingrid Peixoto de , Brandão Eduarda Chagas Santos , Costa Fernanda Helen Melo da , Silva Juliane Cabral , Celestino Raquel Teixeira Silva
Published: March 2022

Introdução: A Cannabis sativa é uma planta utilizada para fins medicinais ou recreativos. No entanto, apesar dos benefícios, ela pode apresentar toxicidade que afeta as condições histológicas do indivíduo conduzindo a alterações patológicas. Objetivo: Analisar na literatura os comprometimentos histopatológicos na toxicidade aguda pelo uso de Cannabis sativa. Material e métodos: Trata-se de uma revisão bibliográfica realizada a partir de buscas na Scientific Electronic Library Online (SciELO), na Biblioteca Virtual em Saúde(BVS) e PubMed com os seguintes Descritores em Ciências da Saúde (DeCS): “(Histology) AND (Cannabis)” para as duas primeiras, enquanto que para PubMed utilizou-se “(Acute Toxicity) AND Cannabis) AND Histology ” AND “Agrochemicals”. Foram identificados 280 artigos durante os últimos 5 anos, sendo excluídos os artigos duplicados e aqueles que não respondessem qual o comprometimento histopatológico nos estudos de toxicidade aguda que utilizaram Cannabis Sativa, bem como revisões, literatura cinzenta, cartas, editoriais, relatos de caso e experiência e os artigos que não se enquadram no período, restando 8 evidências científicas como amostra da pesquisa. Resultados: Identificou-se, após a análise dos artigos, que a toxicidade da Cannabis Sativa está associada a alterações prejudiciais no epitélio seminífero dos testículos com redução significativa no diâmetro, consequente baixos níveis séricos de testosterona e gonadotrofina hipofisária, que provoca espermáticos diminuídos, alta fragmentação de DNA no esperma e fertilidade masculina reduzida. Além disso, mostra-se um aumento da ansiedade e modificações histológicas no tecido adiposo como necrose e inflamação, alterações nos macrófagos intra-alveolares apresentando pigmentados marrons. Ao que se refere ao Sistema nervoso encontram-se pequenas alterações em células, com fragmentação e presença de células picnóticas associadas à redução na densidade neuronal. A exposição à cannabis, especificamente, em gestantes está relacionada a alterações estruturais na retina do feto, deixando-a mais fina e provocando um possível atendimento oftálmico precoce a esse indivíduo. Aponta-se ainda, que durante esse período a exposição à cannabis pode afetar o desenvolvimento do tecido nervoso fetal, causando deficiências neurológicas, hiperatividade, função cognitiva deficiente e alterações nos receptores dopaminérgicos em crianças. Conclusão: Existe uma importante associação entre o uso de Cannabis Sativa, com comprometimento histopatológico de diferentes sistemas do organismo.
GENITÁLIA AMBÍGUA: ASPECTOS PSICOSSOCIAIS ENVOLVIDOS NA DEFINIÇÃO DO SEXO
Authors: Silva Ana Letícya Gomes de Melo , Siqueira Bianca Barbosa de , Silva Emanoel Gomes da , Silva Vinicius Rennan Rodrigues da , Vasconcelos Amanda Soares de
Published: March 2022

Introdução: Genitália Ambígua está associada a alterações na formação embriológica da genitália que podem ser causadas por fatores genéticos, hormonais ou por Hiperplasia Adrenal Congênita. Nessa condição não há presença de características associadas unicamente ao sexo feminino ou masculino. Ainda hoje, na clínica diária, temos situações e conflitos que não permitem um estudo psicossocial do indivíduo levando a uma intervenção precoce. Objetivo: Descrever aspectos psicossociais que envolvem a condução e desfecho dos casos de Genitália Ambígua. Material e métodos: Revisão integrativa na plataforma PubMed, com descritor “Ambiguous Genitalia”. Foram incluídos artigos escritos em português, inglês e espanhol, publicados entre 2018 e 2022, completos e adequados ao tema. Resultados: De 117 artigos encontrados, 7 foram selecionados. Essa condição clínica tem incidência de 1:2000-1:4500 casos, diagnosticados durante o pré ou pós-natal, porém as incertezas e as decisões sobre o manejo são fatores estressores tanto para a equipe de saúde quanto para os familiares - podendo desencadear nestes últimos ansiedade e depressão exacerbados. A declaração do sexo biológico, permitida legalmente em alguns países como neutro, ainda é um assunto que gera bastante debate mundialmente, pois está ligada à tomada de decisão sobre a redesignação sexual e ao consentimento esclarecido. Isso se intensifica pelo caráter social dessa condição, que extrapola o biológico, abrangendo questões sexuais, de gênero, aceitação social e individual, afetando as relações interpessoais do indivíduo principalmente na adolescência, trazendo frustração, ansiedade, angústia, medo, revolta, culpa, tristeza, rejeição. Alguns serviços, trazem a definição do sexo precoce como um atenuador de possíveis traumas nas crianças, somado à resolução para o dilema médico. Porém, o olhar da equipe multidisciplinar para os aspectos psicossociais da condição, das relações familiares, da aceitação das crianças portadoras por ela mesma e pela família, são importantes. Atentando, inclusive, para espera da criança atingir o período de definição sexual ou da puberdade para que ela opte pelo seu sexo definitivo. Conclusão: Os casos de genitália ambígua requerem uma atenção holística durante as várias fases da vida. Sendo fulcral estabelecer equipes multidisciplinares para acompanhamento clínico longitudinal nessas situações, agindo não só no diagnóstico e conduta, mas também no apoio psicológico.
O CONSUMO DE ÁLCOOL DURANTE A GESTAÇÃO E SUAS CONSEQUÊNCIAS NO DESENVOLVIMENTO EMBRIOLÓGICO DO SISTEMA NERVOSO
Authors: Oliveira Júlia Martins , Borges Ana Laura Barra
Published: March 2022

Introdução: Certamente, são inúmeras as consequências provenientes do consumo de álcool para o organismo humano. Na gestação, envolve danos ao desenvolvimento do embrião, devido à facilidade com que o etanol atravessa a barreira placentária, alcançando o líquido amniótico e influenciado no crescimento dos órgãos e tecidos (principalmente pela baixa concentração da enzima álcool-desidrogenase, responsável pela metabolização do álcool). Assim, o Sistema Nervoso é um dos alvos do consumo desta droga, em um contexto de maior liberação de radicais livres que induz estresse oxidativo, danificando proteínas, mitocôndrias e lipídios importantes na formação e manutenção de células nervosas. Objetivo: Realizar uma revisão de literatura acerca da teratogenia do consumo de álcool no período da gestação e as complicações no desenvolvimento embriológico do sistema nervoso. Material e métodos: Foram buscados artigos no Google Acadêmico. Utilizaram-se os descritores: “Desenvolvimento do sistema nervoso” e “Alcoolismo na gestação”. Os critérios de inclusão foram artigos disponíveis na íntegra, no idioma português, entre os anos de 2016 e 2021 que abordavam de forma sistemática o objetivo do trabalho. Resultados: Os estudos realizados evidenciaram um processo neurodegenerativo provocado pela toxicidade da presença do álcool no desenvolvimento embrionário. Dentre os problemas identificados, utiliza-se o termo Síndrome do Alcoolismo Fetal (SAF), sendo uma de suas anomalias frequentes a agenesia do corpo caloso (estrutura responsável pela comunicação entre os hemisférios cerebrais). Nesse contexto, durante o primeiro trimestre de gestação, o ácido retinoico é importante para guiar os padrões de crescimento do embrião, sendo que a sua inibição pela exposição a substâncias alcoólicas determina significativas alterações na organogênese, incluindo nas células formadoras da crista neural. Conclusão: O consumo indiscriminado de drogas lícitas é uma realidade crescente na população feminina. Assim, a falta de conscientização viabiliza essa prática durante a gravidez, gerando consequências no desenvolvimento morfofisiológico do embrião, sendo o sistema nervoso um dos principais prejudicados. Os efeitos, portanto, podem ser observados na incidência de doenças como microcefalia, distúrbios de comportamento e dificuldades motoras. Dessa forma, é essencial a orientação das gestantes acerca da prevenção e cuidados necessários para que o desenvolvimento do embrião não sofra por ação de fatores exógenos como o alcoolismo.
BIGNONIACEAE JUSS. NO PARQUE ESTADUAL DA SERRA DE CALDAS NOVAS, GOIÁS, BRASIL
Authors: Macedo Karise Mamede , Bento Karla Bianca de Deus , Jesus Paulo Antônio Gonçalves de
Published: March 2022

Introdução: Bignoniaceae Juss. é representada no Brasil por 33 gêneros e 417 espécies, sendo 27 gêneros e 103 espécies pertencentes e distribuídas em formações florestais e savânicas de Cerrado do estado de Goiás. Goiás abriga em seu território, importantes áreas de conservação da biodiversidade do Cerrado, como Parque Estadual da Serra de Caldas Novas (localizado nos municípios de Caldas Novas e Rio Quente) que abriga uma significativa quantidade de espécies de Bignoniaceae. Objetivo: Visando contribuir com o conhecimento florístico dessa área, objetivou-se realizar um levantamento de espécies da família ocorrentes no Parque Estadual da Serra de Caldas Novas. Material e métodos: Para a obtenção dos resultados, foram realizadas expedições com duração de dois dias, estudos de coleções herborizadas, consultas a bases de dados digitais e literaturas clássicas. Resultados: Foram registradas 20 espécies, agrupadas em nove gêneros, sendo Jacaranda Juss. o mais numeroso (seis spp); seguido por Fridericia Mart. emend L.G. Lohmann (três spp); Anemopaegma Mart. ex Meisn., Cuspidaria DC., Handroanthus Mattos e Tabebuia Gomes ex DC. (duas spp cada). Os gêneros com menores números de representantes foram Adenocalymma Mart. ex Meisn. emend L.G. Lohmann, Tanaecium Sw. emend L.G.Lohmann e Zeyheria Mart. (uma spp cada). Dentre as espécies encontradas, nenhuma é endêmica do estado de Goiás e crescem principalmente em Cerrado (lato sensu), campos rupestres e vegetações sobre afloramentos rochosos. Quanto à morfologia, as espécies registradas podem ser diferenciadas pelo hábito lianescente (quatro spp), arbustivo (nove spp) ou arbóreo (sete spp) e pela presença (12 spp) ou ausência (oito spp) de tricomas dos tipos tectores e glandulares. A forma da corola também é uma característica importante no reconhecimento das espécies, sendo infundibuliforme (nove spp.), tubular (sete spp) e campanulada (quatro spp); onde apresentam-se nas cores rosa (quatro spp), amarela (seis spp), branca (três spp), magenta (uma spp), roxa (três spp), azul (duas spp) e lilás (uma spp). Gavinhas estão presentes em quatro espécies apenas. Conclusão: O Cerrado é um bioma rico em biodiversidade de espécies de Bignoniaceae, sendo de suma importância ter ciência de tal riqueza, para poder contribuir com o conhecimento e a conservação destes e de outros táxons.
Der Krieg ist bedrohlich nah
Authors: Mende Jan , Tewes Werner , Klug Denise , Stockburger Manfred
Published: March 2022

Nach einer Woche Krieg in der Ukraine ist der Handel dort hart getroffen. Hierzulande sind direkte Auswirkungen auf die Branche momentan noch gering.
Schnelllieferdienste werden langsamer
Authors: Klug Denise
Published: March 2022

Die Quick-Commerce-Anbieter rollen weniger eilig durch die deutschen Metropolen. Keiner bewirbt mehr die Lieferung innerhalb von zehn Minuten. Das soll die Verluste verringern.
Euronics baut Chefetage um
Authors: Klug Denise , Becker Jessica
Published: March 2022

Der ehemalige Media-Saturn-Deutschlandchef Michael Rook rückt in den Euronics-Vorstand. Kai Kürpick, bisher Einkaufsschef bei Media-Saturn, wird Chief Procurement Officer.
Müller tauscht Spanien-Chef aus
Authors: Müller Annette
Published: March 2022

Bei Müller dreht sich erneut das Personalkarussell: Zum zweiten Mal tauscht das Handelsunternehmen den Spanien-Chef aus.
Corona-Öffnung lässt Brauereien hoffen
Authors: Holst Jens
Published: March 2022

Die Brauereien erwarten von der Corona-Öffnung positive Absatzeffekte. Allerdings fordern sie von der Politik künftig eine bessere Planbarkeit der Maßnahmen.
Fripa steigt ins Markengeschäft ein
Authors: Brändlein Philip
Published: March 2022

Der Tissuehersteller Fripa steigt in das Markengeschäft ein. Die Marke Oecolife zielt auf Lifestyle und Nachhaltigkeit ab. Sie soll dem Hersteller zusätzlichen Umsatz bringen und Innovationen vorantreiben.
Neue Funde von Ethylenoxid
Authors: Bender Hanno
Published: March 2022

Bei der Problematik von Ethylenoxid-Rückständen ist keine Entspannung in Sicht. Neue Befunde führen zu Rückrufen, das Efsa-Gutachten bestätigt die BfR-Bewertung und die EU beharrt auf den neuen strengen Importregeln.
Neue Impulse stärken Urbane Logistik
Authors: Bökamp Lena
Published: March 2022

Die Urbane Logistik steht in der letzten Meile der Belieferung vor vielfältigen Herausforderungen. Logistiker und Planer sind gefragt, kreative Lösungen zu finden.
Retouren im E-Commerce kosten viel Geld
Authors: Kempcke Thomas
Published: March 2022

Onlineshops verzeichnen bis zu 50 Prozent Retouren, jedenfalls im Bereich Fashion. Eine Studie des EHI untersucht, wie E-Commerce-Händler versuchen, die Kosten durch zurückgeschickte Ware zu reduzieren.
FMCG-Player machen ihre Lieferketten krisenfest
Authors: Maasmann Julian , Bedaux Pank
Published: March 2022

Eine neue Studie von Miebach Consulting: zeigt, dass viele Unternehmen der FMCG-Branche wegen der durch Anti-Covid-Maßnahmen und Transportprobleme ausgelösten Probleme in den Lieferketten ihre Supply Chains umbauen und besser absichern.
Viele Bausteine verbessern die Letzte Meile
Authors: Manner-Romberg Horst , Zimmermann Janine , Kuchenbecker Michael
Published: March 2022

Die Logix-Studie schätzt die Chancen und Potenziale neuer Lösungen für die Letzte Meile der Belieferung ein. Die These: Nur eine Kombination vieler Bausteine kann die Herausforderungen meistern.
Volle Fahrt
Authors: Bender Ralf
Published: March 2022

Die Agar- und Lebensmittelwirtschaft in den USA und Kanada sind immer stärker auf den Export ausgerichtet. Jedoch müssen sie daran arbeiten, ihre Angebote zu diversifizieren und die Abhängigkeit von bestehenden Märkten zu verringern.
Old El Paso rechnet mit wachsendem Tex-Mex-Markt
Authors: Bender Ralf
Published: March 2022

Seit dem Boom der Tex-Mex-Küche Ende der 90er-Jahre steigt die Nachfrage nun wieder. Diesen Trend will auch die General Mills-Marke Old El Paso nutzen.
„Walnüsse sind nicht alle gleich“
Authors: Bender Ralf
Published: March 2022

Bei einer leichten Steigerung der Anbaufläche auf 385 000 ha haben die kalifornischen Farmer in der Saison 2021/22 rund 670000 t Walnüsse ernten können.
Beam Suntory setzt auf Premium und RTD
Authors: Bender Ralf
Published: March 2022

Im deutschen Spirituosenmarkt gehört Whiskey zu den Wachstumskategorien. Mit seinem breiten Sortiment sieht sich Beam Suntory hier gut aufgestellt.
Die Deutschland-Card wird zum „Glückslos“
Authors: Konrad Jörg
Published: March 2022

Das Loyaltyprogramm Deutschland-Card ist auf Expansionskurs. Geschäftsführer Detlev Rubant erläutert die Strategie – und setzt auch bei möglichen Kooperationen mit Schnelllieferdiensten zunächst auf den Edeka-Verbund.
Kanalinspektion von Großprofilen mittels Drohnentechnik
Authors: Velle Florian
Published: March 2022

Die Inspektion von Abwasserkanälen durch TV-Befahrungen ist seit Jahren Stand der Technik. Dennoch gibt es Situationen, unter denen diese oder eine Begehung nicht möglich sind. Der Einsatz von Kanaldrohnen ist eine zukunftsfähige Option.
Reinigung renovierter Rohrleitungen
Authors: Haacker Reinhild
Published: March 2022

Der Rohrleitungssanierungsverband (RSV) hat sich dem Thema Reinigung von Rohrleitungen angenommen – und zwar speziell mit Blick auf renovierte Leitungen. Die Erkenntnisse mündeten im Juni 2021 in einem Merkblatt.
Das Potenzial von Biostimulanzien ist witterungsabhängig
Authors: Schaal René
Published: March 2022

Biostimulanzien ersetzen Düngung und Pflanzenschutz nicht komplett. In vielen Fällen zeigt sich aber, dass sie positiv auf die Pflanzen wirken – vor allem bei suboptimalen Witterungsbedingungen und Stresssituationen in der Vegetationszeit.
Alte Linsen neu entdeckt
Authors: Behme Dagmar
Published: March 2022

Frankfurt a.M. Die Nachfrage nach pflanzlichem Protein vom heimischen Acker wächst. Das Zentrum Ökologischer Landbau der Universität Hohenheim widmet sich den Chancen von Linsen.
Den Zusammenhalt stärken
Authors: Brust Martin
Published: March 2022

Gemeinsame Kanutour und danach Grillen, und schon kennen sich alle und arbeiten perfekt zusammen? So einfach war es selbst vor Corona schon nicht. In der hybriden Arbeitswelt von morgen ist Teamentwicklung wichtiger denn je. Es reicht aber nicht, einfach nur Events zu buchen.