bluuebunny/crossref_metadata_2025 huggingface dataset:
Transformer-Based Abstractive Summarization for Reddit and Twitter: Single Posts vs. Comment Pools in Three Languages
Authors: Blekanov Ivan S. , Tarasov Nikita , Bodrunova Svetlana S.
Published: February 2022

Abstractive summarization is a technique that allows for extracting condensed meanings from long texts, with a variety of potential practical applications. Nonetheless, today’s abstractive summarization research is limited to testing the models on various types of data, which brings only marginal improvements and does not lead to massive practical employment of the method. In particular, abstractive summarization is not used for social media research, where it would be very useful for opinion and topic mining due to the complications that social media data create for other methods of textual analysis. Of all social media, Reddit is most frequently used for testing new neural models of text summarization on large-scale datasets in English, without further testing on real-world smaller-size data in various languages or from various other platforms. Moreover, for social media, summarizing pools of texts (one-author posts, comment threads, discussion cascades, etc.) may bring crucial results relevant for social studies, which have not yet been tested. However, the existing methods of abstractive summarization are not fine-tuned for social media data and have next-to-never been applied to data from platforms beyond Reddit, nor for comments or non-English user texts. We address these research gaps by fine-tuning the newest Transformer-based neural network models LongFormer and T5 and testing them against BART, and on real-world data from Reddit, with improvements of up to 2%. Then, we apply the best model (fine-tuned T5) to pools of comments from Reddit and assess the similarity of post and comment summarizations. Further, to overcome the 500-token limitation of T5 for analyzing social media pools that are usually bigger, we apply LongFormer Large and T5 Large to pools of tweets from a large-scale discussion on the Charlie Hebdo massacre in three languages and prove that pool summarizations may be used for detecting micro-shifts in agendas of networked discussions. Our results show, however, that additional learning is definitely needed for German and French, as the results for these languages are non-satisfactory, and more fine-tuning is needed even in English for Twitter data. Thus, we show that a ‘one-for-all’ neural-network summarization model is still impossible to reach, while fine-tuning for platform affordances works well. We also show that fine-tuned T5 works best for small-scale social media data, but LongFormer is helpful for larger-scale pool summarizations.
Novel Water–Oil Mixed Frying: Fried Oil Quality and the Formation of Heterocyclic Amines and Trans Fatty Acids in Fried Duck
Authors: Jamali Muneer Ahmed , Wang Zhen , Zhu Yuxia , Zhang Yawei
Published: February 2022

The present study was conducted to explore the impact of novel water–oil mixed frying and traditional oil frying methods on the soybean oil quality and formation of trans fatty acids (TFAs) and heterocyclic amines (HCAs) in fried duck breast and skin during 60 frying cycles. The acid value of the soybean oil was 2.10 mg/g using the traditional oil frying and 1.08 mg/g using water–oil mixed frying at the 60th frying cycle. The peroxide value of the water–oil mixed fried soybean oil was significantly lower than that of the traditional frying method. Water–oil mixed frying delayed the formation of TFAs in the soybean oil. The traditionally oil fried skin showed increased TFAs (9tC16:1) content from 0.17 to 0.22 mg/g (29.4% increase), while those of the water–oil mixed fried samples increased from 0.16 to 0.20 mg/g (25.00% increase) compared to control. Harman, Norharman and AαC were detected in all the fried samples and PhIP was observed after the 20th frying cycle, while MeAαC was formed only at the 60th frying cycle in traditional fried duck breast. Therefore, it is concluded that the water–oil mixed frying method is more suitable to improve the quality and safety of fried duck skin and breast meat.
Postharvest Ultraviolet Radiation in Fruit and Vegetables: Applications and Factors Modulating Its Efficacy on Bioactive Compounds and Microbial Growth
Authors: Darré Magalí , Vicente Ariel Roberto , Cisneros-Zevallos Luis , Artés-Hernández Francisco
Published: February 2022

Ultraviolet (UV) radiation has been considered a deleterious agent that living organisms must avoid. However, many of the acclimation changes elicited by UV induce a wide range of positive effects in plant physiology through the elicitation of secondary antioxidant metabolites and natural defenses. Therefore, this fact has changed the original UV conception as a germicide and potentially damaging agent, leading to the concept that it is worthy of application in harvested commodities to take advantage of its beneficial responses. Four decades have already passed since postharvest UV radiation applications began to be studied. During this time, UV treatments have been successfully evaluated for different purposes, including the selection of raw materials, the control of postharvest diseases and human pathogens, the elicitation of nutraceutical compounds, the modulation of ripening and senescence, and the induction of cross-stress tolerance. Besides the microbicide use of UV radiation, the effect that has received most attention is the elicitation of bioactive compounds as a defense mechanism. UV treatments have been shown to induce the accumulation of phytochemicals, including ascorbic acid, carotenoids, glucosinolates, and, more frequently, phenolic compounds. The nature and extent of this elicitation have been reported to depend on several factors, including the product type, maturity, cultivar, UV spectral region, dose, intensity, and radiation exposure pattern. Even though in recent years we have greatly increased our understanding of UV technology, some major issues still need to be addressed. These include defining the operational conditions to maximize UV radiation efficacy, reducing treatment times, and ensuring even radiation exposure, especially under realistic processing conditions. This will make UV treatments move beyond their status as an emerging technology and boost their adoption by industry.
The Evolution of Ambiguity in Sender—Receiver Signaling Games
Authors: Mühlenbernd Roland , Wacewicz Sławomir , Żywiczyński Przemysław
Published: February 2022

We study an extended version of a sender–receiver signaling game—a context-signaling (CS) game that involves external contextual cues that provide information about a sender’s private information state. A formal evolutionary analysis of the investigated CS game shows that ambiguous signaling strategies can achieve perfect information transfer and are evolutionarily stable. Moreover, a computational analysis of the CS game shows that such perfect ambiguous systems have the same emergence probability as non-ambiguous perfect signaling systems in multi-agent simulations under standard evolutionary dynamics. We contrast these results with an experimental study where pairs of participants play the CS game for multiple rounds with each other in the lab to develop a communication system. This comparison shows that unlike virtual agents, human agents clearly prefer perfect signaling systems over perfect ambiguous systems.
The GRB Prompt Emission: An Unsolved Puzzle
Authors: Bošnjak Željka , Barniol Duran Rodolfo , Pe’er Asaf
Published: February 2022

The recent multi-messenger and multi-wavelength observations of gamma-ray bursts (GRBs) have encouraged renewed interest in these energetic events. In spite of the substantial amount of data accumulated during the past few decades, the nature of the prompt emission remains an unsolved puzzle. We present an overview of the leading models for their prompt emission phase, focusing on the perspective opened by future missions.
Identification of Immune Markers in Dilated Cardiomyopathies with Heart Failure by Integrated Weighted Gene Coexpression Network Analysis
Authors: Wang Xuehua , Guan Hongquan , Liu Wei , Li Huili , Ding Jiaxing , Feng Yu , Chen Zhijian
Published: February 2022

Dilated cardiomyopathy (DCM), a heterogeneous cardiomyopathy, is a major cause of heart failure and heart transplant. Currently, immunotherapy is believed to be an effective treatment method for DCM. However, individual differences are so obvious that the clinical effect is not satisfactory. In order to find immune-related biomarkers of DCM to guide treatment and improve clinical efficacy, we downloaded a GSE120895 dataset from the Gene Expression Omnibus (GEO) database using CIBERSORT and WGCNA algorithms in RStudio and visualizing the protein–protein interaction (PPI) network for key modules by Cytoscape, and finally obtained six hub genes. A GSE17800 dataset was downloaded from the GEO dataset to verify the diagnostic values of hub genes, MYG1, FLOT1, and ATG13, which were excellent. Our study revealed unpublished potential immune mechanisms, biomarkers, and therapeutic targets of DCM.
Lost Heritage. Architectural Replacement of an Atrium and a Courtyard of the Roman Houses of Armea (Allariz, Ourense)
Authors: Lago Cerviño Marta , Fernández Fernández Adolfo , Rodríguez Nóvoa Alba Antía , Valle Abad Patricia
Published: February 2022

Francisco Conde-Valvís’s so-called “stone treasure” is a set of unique carved stone pieces, such as bases, column shafts, a mortar, and decorated fragments (trisqueles and rosettes), found during the 2018 excavation campaign in the Cibdá de Armea (Allariz, Ourense). They had been piled up and re-buried—no records existed as to where—at the western end of the Finca de A Atalaia, which was excavated in the 1950s under the direction of Conde-Valvís and began to be excavated again in 2011. The thorough review of the graphic and textual material available from the old excavations allowed us to determine the original archaeological context of the pieces. Most of these elements belonged to the atria of the so-called “Domus of Hexasquel” (North house) and “Domus of the Rosette” (South house). Once we established the origin of all the elements, especially with the aid of the old photographs, it was decided to reintegrate them into the site, to increase the educational and interpretive value of Armea, instead of burying them indefinitely in the warehouses of a museum.
Sarcopenic Obesity Tendency and Nutritional Status Is Related to the Risk of Sarcopenia, Frailty, Depression and Quality of Life in Patients with Dementia
Authors: Chou Hsi-Hsien , Lai Te-Jen , Yen Chi-Hua , Chang Po-Sheng , Pan Ji-Cyun , Lin Ping-Ting
Published: February 2022

The purpose of this study was to investigate the nutritional status of dementia patients and examine the correlation with sarcopenia, frailty, depression, and quality of life. We enrolled patients aged 60 years and over with Mini Mental State Examination (MMSE) scores ≤ 26 (Taiwan), and dementia diagnosed by a neurologist or psychiatrist. Nutritional status was assessed with the Mini Nutritional Assessment (MNA). Muscle mass was measured by dual-energy X-ray absorptiometry. Muscle strength and endurance were evaluated by handgrip, leg-back strength, dumbbell curls, sit to stand test, and gait speed. Quality of life, frailty, and depression status were measured by questionnaires. Patients with moderate dementia (MMSE ≤ 20) had a significantly lower MNA score, muscle function, and quality of life than patients with mild dementia (p < 0.01). A lower MNA score was significantly associated with the risk of frailty (odds ratio: 4.76, p < 0.01), depression (odds ratio: 3.17, p = 0.03), and poor quality of life (odds ratio: 2.73, p < 0.05), and sarcopenia (odds ratio: 3.97, p = 0.03) after adjusting for potential confounders. In conclusion, patients with dementia were at risk of malnutrition, and nutritional status was associated to the risk of sarcopenia, frailty, depression, and quality of life.
Understanding Trustful Relationships between Community Health Workers and Vulnerable Citizens during the COVID-19 Pandemic: A Realist Evaluation
Authors: Vanden Bossche Dorien , Willems Sara , Decat Peter
Published: February 2022

(1) Background: Community health workers (CHWs) are an essential public health workforce defined by their trustful relationships with vulnerable citizens. However, how trustful relationships are built remains unclear. This study aimed to understand how and under which circumstances CHWs are likely to build trust with their vulnerable clients during the COVID-19 pandemic. (2) Methods: We developed a program theory using a realist research design. Data were collected through focus groups and in-depth interviews with CHWs and their clients. Using a grounded theory approach, we aimed to unravel mechanisms and contextual factors that determine the trust in a CHW program offering psychosocial support to vulnerable citizens during the COVID-19 pandemic. (3) Results: The trustful relationship between CHWs and their clients is rooted in three mental models: recognition, equality, and reciprocity. Five contextual factors (adopting a client-centered attitude, coordination, temporariness, and link with primary care practice (PCP)) enable the program mechanisms to work. (4) Conclusions: CHWs are a crucial public health outreach strategy for PCP and complement and enhance trust-building by primary care professionals. In the process of building trustful relationships between CHWs and clients, different mechanisms and contextual factors play a role in the trustful relationship between primary care professionals and patients. Future research should assess whether these findings also apply to a non-covid context, to the involvement of CHWs in other facets of primary healthcare (e.g., prevention campaigns, etc.), and to a low- and middle-income country (LMIC) setting. Furthermore, implementation research should elaborate on the integration of CHWs in PCP to support CHWs in developing the mental models leading to build trust with vulnerable citizens and to establish the required conditions.
Congestive Nephropathy
Authors: D’ Marco Luis
Published: February 2022

The complex interaction between cardiac and renal functions is known. However, when these functions are disrupted, many intricate and sensitive interactions between these organs are failed by several pathophysiological ways. As a result, this malfunction is clinically evident by sign and symptoms associated to intravascular and interstitial congestion. In this sense, the adverse impact of venous congestion on renal function has long been recognized. Currently, the presence of a specific subtype of nephropathy associated to congestion has been suggested. Even though no diagnosis criteria has been clearly stablished, and no renal specific histological pattern were reported; studies regarding this issue may help to improve the handling and therapeutic principles in affected patients.
Do the Benefits of School Closure Outweigh Its Costs?
Authors: Raffetti Elena , Di Baldassarre Giuliano
Published: February 2022

School closure has been a common response to COVID-19. Yet, its implementation has hardly ever been based on rigorous analysis of its costs and benefits. We aim to first illustrate the unintended consequences and side effects of school closure, and then discuss the policy and research implications. This commentary frames evidence from the most recent papers on the topic from a public-health epidemiology and disaster risk reduction perspective. In particular, we argue that the benefits of school closure in terms of reduced infection rates should be better compared with its costs in terms of both short- and long-term damage on the physical, mental, and social well-being of children and society at large.
The Healing Power of Clean Rivers: In Silico Evaluation of the Antipsoriatic Potential of Apiin and Hyperoside Plant Metabolites Contained in River Waters
Authors: Roviello Valentina , Gilhen-Baker Melinda , Vicidomini Caterina , Roviello Giovanni N.
Published: February 2022

Humanity may benefit greatly from intact riverine ecosystems not only because they supply water to be used in the most common human activities, but also for the effects that clean rivers can have on human health. Herein, we used a computational approach to show that some phytochemicals produced by riparian plants as secondary metabolites, which are naturally released into river waters, can have therapeutic properties. These include antipsoriatic activities which we demonstrated in silico by modelling the interaction of apiin, guanosine and hyperoside, a few main river plant metabolites, with NF-kB, IL-17 and IL-36, which are recognized targets involved in psoriasis disease. In particular, we found that apiin and hyperoside are endowed with docking energies and binding affinities which are more favorable than the known reference inhibitors of the three protein targets whilst, in silico, guanosine shows comparable activity with respect to the inhibitors of IL-36 and NF-kB. The low skin permeation (logKp < −8) we predicted for apiin and hyperoside led us to hypothesize their possible utilization as topic antipsoriatic therapeutics, and in particular after PAINS (pan-assay interference compounds) score evaluation, we reached the conclusion that apiin, with no predicted tendency to react nonspecifically with the numerous targets involved in the biological cellular pathways, is particularly interesting for the desired therapeutic application.
Recent Climatology (1991–2020) and Trends in Local Warm and Cold Season Extreme Temperature Days and Nights in Arabia
Authors: Alghamdi Ali S.
Published: February 2022

The Arabian Peninsula (Arabia) is among the places to have experienced the greatest amount of warming during recent decades, and this trend is projected to continue. Specifics related to the characteristics (frequency, duration, and intensity) of extreme temperature events (ETEs) over Arabia as a whole are either largely outdated or limited only to specific areas. The seasonal ETE definitions commonly used in local studies are neither climatological- nor phenomenon-based. Using a novel and straightforward framework, the seasons of four extreme temperature types (extreme warm days/nights (EWDs/EWNs) and extreme cold days/nights (ECDs/ECNs)) were identified on the simultaneous basis of event occurrence and impact times. Assessments of ETE frequency, duration, and intensity and their recent changes were then provided based on the most recent climate data (1991–2020). Results showed that the use of traditional seasonal definitions (e.g., meteorological seasons) tends to assume a spatiotemporal homogeneity in the seasonality of ETEs and their potential risk levels throughout the year. The developed framework distinguished months with events that have larger potential impacts together with their local seasons. ETE seasons were found to vary at the regional and local scales and are better defined at both the local and phenomenon levels. Early extreme warm events were hotter, and those at locations with longer local warm seasons demonstrated higher intensities. ECDs tended to be more frequent at coastal locations, whereas ECNs were more frequent over southwestern Arabia. Early and late extreme cold events were much colder than those occurring mid-season. Trend analyses revealed generally increasing regional trends in the frequency of extreme warm events, whereas extreme cold events have declined. The duration (i.e., consecutive occurrences) and intensity of EWNs have been increasing at more locations, suggesting that urgent attention is needed within such an arid and hot climate type in which nighttime stress relief is already very limited.
Content Analysis of Skin Cancer Screenings on Pinterest: An Exploratory Study
Authors: Merten Julie , King Jessica , Dedrick Ashley
Published: February 2022

Skin cancer rates are rising in the United States, yet screening rates remain low. Meanwhile, social media has evolved to become a primary source of health information, with 40% of daily users of Pinterest reporting the platform as a “go-to” source. The objective of this research paper is to examine how skin cancer screenings were portrayed on Pinterest. Using the search terms “skin cancer screening” and “skin cancer exam”, researchers sampled every fifth pin to collect 274 relevant pins. Two researchers coded the pins, and interrater agreement was established at 94%. The results showed that twenty-two percent of the sample depicted skin cancer screening in a negative way, yet 41.5% noted that early detection leads to better outcomes. The pins were geared toward younger, white women with minimal depiction of people of color. Few pins included comprehensive information about skin cancer risk factors, importance of routine self-screenings, or what to expect with a medical provider. Fifty-eight percent of pins included links to personal blogs. In conclusion, social media has become a powerful source of health information, yet much of the posted information is incomplete. These findings present public health experts with an opportunity to disseminate more comprehensive skin cancer screening information on social media.
Occurrence of Idiopathic Pulmonary Fibrosis in Italy: Latest Evidence from Real-World Data
Authors: Iommi Marica , Bonifazi Martina , Faragalli Andrea , Latini Lara Letizia , Mei Federico , Spazzafumo Liana , Skrami Edlira , Ferrante Luigi , Carle Flavia , Gesuita Rosaria
Published: February 2022

The aim of the study was to evaluate the trend in the incidence of idiopathic pulmonary fibrosis (IPF) in a real-world setting of the Marche region, a region of Central Italy, between 2014 and 2019. This observational prospective study was based on administrative databases of hospital discharges and drug prescriptions. All adult residents in the Marche Region with a first prescription of antifibrotic drugs, or a first hospitalization with a diagnosis of IPF during the study period, were identified as incident cases of IPF. A multiple Poisson regression analysis was used to estimate the IPF incidence trend, adjusted for age, sex, and health conditions. The mean incidence rate was 9.8 cases per 100,000 person-years. A significant increasing trend of 6% per year was observed. The incidence rates were significantly higher in males than females, older subjects, and those with poorer health conditions. To our knowledge, this is the first study evaluating incidences of IPF over a 6-year period in Italy, combining hospital discharge and drug prescription databases. The study highlights that the combined use of two secondary sources is a reliable strategy to accurately identify new cases of IPF when the appropriate disease registry is lacking.
Public Perception of Pharmacists in Poland
Authors: Andrzejewska Maja , Religioni Urszula , Piątkiewicz Paweł , Barańska Agnieszka , Herda Jolanta , Czerw Aleksandra , Krysiński Jerzy , Merks Piotr
Published: February 2022

Background. Pharmacists constitute one of the largest groups of medical professionals and play a significant role in public health. Pharmaceutical care in community pharmacies is one of the key elements that impact the clinical outcomes of patients. The main objective of this study was to evaluate the public perception of pharmacists in Poland, as well as the knowledge of and willingness of Polish people to use pharmaceutical care services. Methods. This study was carried out in 2017 on 1435 people. The research tool was an anonymous online questionnaire. Results. Of the participants, 61% considered pharmacists to have a position of public trust, and 25% trusted pharmacists to a lesser extent than representatives of other medical professions. The participants stated that pharmacists were kind (74%) and helpful (69%). For 52% of the participants, pharmacists were fully competent to provide information on medications. Twenty-eight percent of the participants ask pharmacists for advice related to medicinal products. Poles’ knowledge on pharmaceutical care was low (44% of the respondents knew this notion). Sixty-six percent of the participants were willing to use pharmaceutical consultations (43% free of charge, and 23% for a nominal fee). Conclusions. Although the overall perception of patients towards pharmacists was positive in Poland, it is essential to educate patients on the possibilities of using pharmaceutical services, and to promote the role of pharmacists in healthcare systems.
Psychometric Properties of Quality of Life Questionnaires for Patients with Breast Cancer-Related Lymphedema: A Systematic Review
Authors: Meilani Estu , Zanudin Asfarina , Mohd Nordin Nor Azlin
Published: February 2022

Backgrounds: Assessing quality of life (QoL) using a well-developed and validated questionnaire is an essential part of a breast cancer-related lymphedema (BCRL) treatment. However, a QoL questionnaire with the best psychometric properties is so far unknown. The aim of this systematic review is to evaluate the psychometric properties of the questionnaires measuring the QoL of patients with BCRL. Methods: A thorough search was performed to identify published studies in electronic databases such as Medline (via Ovid), EBSCOhost, PubMed, Scopus, and Web of Science, on 8 February 2022, by using search terms as follows: ‘quality of life’; ‘breast cancer’; ‘upper limb’; ‘lymphedema’; ‘questionnaire’; and ‘measurement properties.’ Two reviewers conducted article selection, data extraction, and quality assessment independently. The third reviewer helped solve any possible disagreements between the two reviewers. The COSMIN checklist and manual were used to assess the quality of included studies. Results: A total of nineteen articles with nine questionnaires were included and assessed using the COSMIN Risk of Bias checklist. Most studies only assessed content validity, structural validity, internal consistency, reliability, and construct validity. Lymph-ICF-UL showed the most ‘sufficient’ and ‘high’ quality of evidence ratings for its measurement properties. Conclusion: The most appropriate questionnaire for use based on our assessment is Lymph-ICF-UL.
Parenting Record Handbook: The Needs of Mothers Raising Low Birth Weight Infants
Authors: Tomoyasu Yukiko , Sobue Ikuko , Rahman Md Moshiur
Published: February 2022

This study investigated the necessity for a parenting record handbook that is specifically tailored to the needs of low birth weight infants (LBWIs) and their families, especially mothers, who face parenting difficulties and challenges. The participants were 20 mothers, raising LBWIs, discharged from the neonatal intensive care unit. The mean age and weight of the children were 2.75 ± 0.35 years and 1417.50 ± 152.06 g, respectively; the mean duration of neonatal intensive care unit hospitalization was 78.75 ± 14.10 days. At the time of the study, 35% (7/20) were nursery children, 10% (2/20) were kindergarten children, 20% (4/20) were using rehabilitation centers, and 10% (2/20) were using the medical rehabilitation handbook. The needs of the mothers were investigated through focus group interviews or individual interviews, and content analyses were performed. The mothers required the promotion of peer support that assists the alleviation of mental burden and postpartum mental and physical care, as well as the publication of counseling service counters and reliable information sources for parenting difficulties in the parenting record handbook. The mothers required the publication and recording of the growth indicators of LBWIs, parenting records, information management of children since birth, and for the handbook to function as a multidisciplinary information sharing tool. In addition, the requirements for the parenting record handbook were the early provision of the parenting record handbook and measures to cope with poor maternal physical condition. The results of this study suggest that mothers with LBWIs require a parenting record handbook that can provide comprehensive maternal and child health assurance, starting from pregnancy, to resolve childcare difficulties for LBWIs, as well as mental support.
The Effect of Prenatal Exposure to Climate Anomaly on Adulthood Cognitive Function and Job Reputation
Authors: Tang Hong , Di Qian
Published: February 2022

Background: The long-term effect of abnormal climate on cognitive function and socioeconomic status remains elusive. We explored the association between prenatal exposure to climate anomaly and adulthood cognitive function and job reputation. Methods: We obtained repeated cognitive and job reputation measurements from 17,105 subjects for the years 2010, 2014, and 2018, and ascertained their birth date and other covariates. We used sea surface temperature (SST) anomalies in the Southern Pacific Ocean as the indicator for global climate anomaly in the main analyses. We calculated its averaged values for different gestational periods and analyzed its possible nonlinear associations with adulthood cognitive function and job reputation. We also calculated associated economic loss due to prenatal exposure to abnormal climate. Results: We found an inverted U-shaped curve between climate anomaly and adulthood cognition. During the entire pregnancy, for SST anomalies increasing/decreasing 1 °C from 0 °C, newborn individuals will have adulthood cognition (measured by math test) changed by −2.09% (95% confidence interval (CI): −2.31%, −1.88%) and −3.98% (95% CI: −4.32%, −3.65%), respectively. We observed a similar inverted U-shaped pattern for cognitive function measured by word test and job reputation. Such an association is likely to be mediated by regional meteorological conditions, not local ones. Subgroup analyses identified females and people from less-developed regions as even more vulnerable to prenatal abnormal climate, finding an interactive effect with other social factors. The economic loss was assessed as the salary reduction due to declined cognition among all newborn individuals in China. For SST anomalies increasing/decreasing by 1 °C from 0 °C, individuals born each year in China would earn 0.33 (95% CI: 0.40, 0.25) and 1.09 (95% CI: 1.23, 0.94) billion U.S. dollars equivalent less in their annual salary at adulthood because of lowered cognitive function, respectively. Conclusion: Prenatal exposure to abnormal global climate patterns can result in declined adulthood cognitive function, lowered job reputation, and subsequent economic loss.
Long-Term PM2.5 Exposure Is Associated with Symptoms of Acute Respiratory Infections among Children under Five Years of Age in Kenya, 2014
Authors: Larson Peter S. , Espira Leon , Glenn Bailey E. , Larson Miles C. , Crowe Christopher S. , Jang Seoyeon , O’Neill Marie S.
Published: February 2022

Introduction: Short-term exposures to air pollutants such as particulate matter (PM) have been associated with increased risk for symptoms of acute respiratory infections (ARIs). Less well understood is how long-term exposures to fine PM (PM2.5) might increase risk of ARIs and their symptoms. This research uses georeferenced Demographic Health Survey (DHS) data from Kenya (2014) along with a remote sensing based raster of PM2.5 concentrations to test associations between PM2.5 exposure and ARI symptoms in children for up to 12 monthly lags. Methods: Predicted PM2.5 concentrations were extracted from raster of monthly averages for latitude/longitude locations of survey clusters. These data and other environmental and demographic data were used in a logistic regression model of ARI symptoms within a distributed lag nonlinear modeling framework (DLNM) to test lag associations of PM2.5 exposure with binary presence/absence of ARI symptoms in the previous two weeks. Results: Out of 7036 children under five for whom data were available, 46.8% reported ARI symptoms in the previous two weeks. Exposure to PM2.5 within the same month and as an average for the previous 12 months was 18.31 and 22.1 µg/m3, respectively, far in excess of guidelines set by the World Health Organization. One-year average PM2.5 exposure was higher for children who experienced ARI symptoms compared with children who did not (22.4 vs. 21.8 µg/m3, p < 0.0001.) Logistic regression models using the DLNM framework indicated that while PM exposure was not significantly associated with ARI symptoms for early lags, exposure to high concentrations of PM2.5 (90th percentile) was associated with elevated odds for ARI symptoms along a gradient of lag exposure time even when controlling for age, sex, types of cooking fuels, and precipitation. Conclusions: Long-term exposure to high concentrations of PM2.5 may increase risk for acute respiratory problems in small children. However, more work should be carried out to increase capacity to accurately measure air pollutants in emerging economies such as Kenya.
Gender Differences in the Epidemiological Characteristics and Long-Term Trends of Injuries in Taiwan from 1998 to 2015: A Cross-Sectional Study
Authors: Chou Pin-San , Huang Shi-Hao , Chung Ren-Jei , Huang Yao-Ching , Chung Chi-Hsiang , Wang Bing-Long , Sun Chien-An , Huang Shu-Min , Lin I-Long , Chien Wu-Chien
Published: February 2022

Objective: This study used a long-term trend analysis to investigate whether gender differences were related to the risk of injury and epidemiological characteristics in Taiwan from 1998 to 2015. Materials and methods: Data on 4,647,259 hospitalized patients that were injured from 1 January 1998, to 31 December 2015 were collected from the National Health Insurance Research Database (NHIRD). Among the injured patients, 2,721,612 males and 1,925,446 females were identified. Patients were age-, gender-, and index date-matched. Multiple logistic regression was used to analyze the risks of injury via gender differences. A p-value < 0.05 was considered significant. Results: The injury risk of the male patients was 1.4 times higher than that of female patients (AOR = 1.427, 95% CI = 1.40–1.44). The rising trend of male injured hospitalized patients was also greater than that of female injured hospitalized patients. Conclusion: Males were more at risk of injury than females. Gender differences were related to the increased risk of epidemiological characteristics of injury.
Teledermatology versus Face-to-Face Dermatology: An Analysis of Cost-Effectiveness from Eight Studies from Europe and the United States
Authors: López-Liria Remedios , Valverde-Martínez María Ángeles , López-Villegas Antonio , Bautista-Mesa Rafael Jesús , Vega-Ramírez Francisco Antonio , Peiró Salvador , Leal-Costa Cesar
Published: February 2022

(1) Background: The aim of this systematic review was to compare the cost-effectiveness of two follow-up methods (face-to-face and telemedicine) used in dermatology in the last ten years. (2) Methods: A search for articles that included economic analyses was conducted in August 2021 in the databases PubMed, Medline, Scielo and Scopus using the following keywords: “Cost–Benefit Analysis”, “Dermatology”, “Telemedicine”, “Primary Health Care”, as well as other search terms and following the PICOS eligibility criteria. (3) Results: Three clinical trials and five observational studies were analyzed, providing information for approximately 16,539 patients (including four cost-minimization or saving analyses, three cost-effectiveness analyses, and one cost–utility analysis) in Europe and the United States. They describe the follow-up procedures in each of the cases and measure and analyze the direct and indirect costs and effectiveness. All the articles indicate that teledermatology lowers costs and proves satisfactory to both patients and professionals. (4) Conclusions: Although it has been found that follow-up via teledermatology can be more efficient than traditional hospital follow-up, more work is needed to establish evaluation protocols and procedures that measure key variables more equally and demonstrate the quality of the evidence of said studies.
Patient Perceptions on Receiving Vaccination Services through Community Pharmacies
Authors: Kowalczuk Anna , Wong Alexandre , Chung Kevin , Religioni Urszula , Świetlik Dariusz , Plagens-Rotman Katarzyna , Cameron Jameason , Neumann-Podczaska Agnieszka , Fehir Šola Katarina , Kazmierczak Justyna , Blicharska Eliza , Vaillancourt Regis , Merks Piotr
Published: February 2022

(1) Introduction: Pharmacists are medical professionals who play an active role in the protection of public health. Since 2021, pharmacists with an appropriate certification have been authorised to administer vaccines against COVID-19. (2) Objective: The objective of this study was to ascertain the perceptions of patients about receiving vaccinations through community pharmacies. (3) Material and methods: This study was conducted in 2021. The research tool was an anonymous questionnaire published on the websites of patient organisations. Ultimately, 1062 patients participated in this study. (4) Results: This study shows that most of the respondents find community pharmacies more accessible than outpatient clinics (85.3%). Sixty-one percent of the respondents stated that getting vaccinated at pharmacies would be less time consuming than at outpatient clinics. Nearly every third respondent (29.5%) declared that they would get vaccinated if they received such a recommendation from a pharmacist. Fifty-six percent of the respondents were of the opinion that the administration of vaccines by pharmacists would relieve the burden on medical staff and the healthcare system. (5) Conclusions: Polish patients participating in the study have a positive attitude towards the implementation of vaccination services in community pharmacies as an effective way of combating infectious diseases.
Asthma-Related Knowledge and Practices among Mothers of Asthmatic Children: A Latent Class Analysis
Authors: Fasola Salvatore , Malizia Velia , Ferrante Giuliana , Licari Amelia , Montalbano Laura , Cilluffo Giovanna , La Grutta Stefania
Published: February 2022

Mothers’ knowledge about childhood asthma influences management practices and disease control, but validating knowledge/practice questionnaires is difficult due to the lack of a gold standard. We hypothesized that Latent Class Analysis (LCA) could help identify underlying mother profiles with similar knowledge/practices. A total of 438 mothers of asthmatic children answered a knowledge/practice questionnaire. Using answers to the knowledge/practice questionnaire as manifest variables, LCA identified two classes: Class 1, “poor knowledge” (33%); Class 2, “good knowledge” (67%). Classification accuracy was 0.96. Mothers in Class 2 were more likely to be aware of asthma-worsening factors and indicators of attacks. Mothers in Class 1 were more likely to prevent exposure to tobacco smoke (91.1% vs. 78.8%, p = 0.005). For attacks, mothers in Class 2 were more likely to go to the emergency department and follow the asthma action plan. Mothers in Class 2 more frequently had a high education level (79.5% vs. 65.2%, p = 0.004). Children in Class 2 more frequently had fully controlled asthma (36.7% vs. 25.9%, p = 0.015) and hospitalizations for attacks in the previous 12 months (24.2% vs. 10.7%, p = 0.003). LCA can help discover underlying mother profiles and plan targeted educational interventions.
The Effects of Providing Advance Notice and Stress-Coping Traits on Physiological Stress of Patients during Dental Treatment
Authors: Umemori Sachi , Noritake Kanako , Tonami Ken-ichi , Le Son Hoang , Sunaga Masayo , Kimura Yasuyuki , Kanamori Yuna , Sekiguchi Ayako , Nitta Hiroshi
Published: February 2022

Patients tend to feel stress in association with dental treatment due to uneasiness and fear. We investigated the effects of providing advance notice and stress-coping traits on the physiological stress of patients during dental treatment. Sixty non-dental professionals (male, n = 26; female, n = 34; mean age, 49.9 years) were recruited for this study and informed consent was obtained. Subjects were given simulated dental treatment including three stimuli, air, percussion and running of an air turbine, with or without advance notice of the stimulation during dental treatment. Real-time sympathetic nerve activity (SN) and parasympathetic nerve activity (PN) during the treatment were measured using a biological information monitor. The stress-coping traits of each subject were examined using the Lazarus-Type Stress Coping Inventory (SCI). Correlations between the nerve-activity and scores of eight stress-coping strategies of SCI and the presence/absence of advance notice were analyzed. Age, types of stimuli and order of stimuli significantly affected SN, while age, types of stimuli, and the pattern of stimulation significantly affected PN. The interaction of the stress-coping trait and presence/absence of advance notice significantly affected PN. Providing advance notice may have different effects on physiological stress depending on how the patient copes with stress.
How Anthropometrics of Young and Adolescent Swimmers Influence Stroking Parameters and Performance? A Systematic Review
Authors: Alves Miriam , Carvalho Diogo D. , Fernandes Ricardo J. , Vilas-Boas João Paulo
Published: February 2022

The purpose of this systematic review was to investigate the relationship between anthropometric characteristics, biomechanical variables and performance in the conventional swimming techniques in young and adolescent swimmers. A database search from 1 January 2001 to 30 June 2021 was done according to the PRISMA statement, with 43 studies being selected for analysis. Those manuscripts were divided in butterfly, backstroke, breaststroke and front crawl techniques as main categories. The results showed the importance of the anthropometric variables for the performance of the young swimmer, although there was a lack of variables common to the studies that analysed the butterfly, backstroke and breaststroke techniques. For the front crawl technique there is a consensus among studies on the advantage of having higher height and arm span values, variables that concurrently with high body mass and lean body mass values, contribute positively to better stroke length and stoke index values.
In It for the Long Haul: RE-AIM Evaluation of a Preschool Programme Implementing and Maintaining Adult-Initiated Motor Skill Development and Physical Activity across a Two-Year Period
Authors: Nielsen Jonas Vestergaard , Skovgaard Thomas , Klein-Wengel Trine Top , Troelsen Jens
Published: February 2022

Good motor skills (MS) are considered important for children’s social, psychological and physical development and general physical activity (PA) levels. The Motor skill in Preschool study (MiPS) aimed to optimize children’s MS through weekly PA sessions. The aim of this study is to use the RE-AIM framework to report the two-year implementation process of MiPS since the programme’s initiation. Data were collected through a staff questionnaire based on the RE-AIM framework. Data were collected at three months, one year and two years after initiation. Results show that the pedagogical staff believes that the programme promotes MS in children. Implementation measures only showed medium to low fidelity concerning the core element of performing adult-initiated PA sessions with a duration of at least 45 min 4 days a week. The largest barrier was finding the time to plan these PA sessions. Still, the content of the PA sessions achieved high fidelity scores and the programme was deemed suitable for staff’s everyday practice and in alignment with the stated pedagogical goals. The mandatory competence development course was highly valued as strong implementation support. It is notable that there is a large variation in the implementation among the preschools with some struggling more than others.
Intervention for Children with Obesity and Overweight and Motor Delays from Low-Income Families: Fostering Engagement, Motor Development, Self-Perceptions, and Playtime
Authors: Berleze Adriana , Valentini Nadia Cristina
Published: February 2022

Obesity is increasing globally, affecting children’s health and development. This study examines the influence of a motor skill intervention on the daily routine, self-perceptions, body mass index, motor development, and engagement in physical education lessons of children with obesity and overweight with motor delays. Children were randomly assigned to intervention and control groups. The daily routine at home, self-perceptions, motor development, BMI, and engagement were assessed. Significant group by time interactions were found for play (p < 0.0001) and television (p < 0.0001) time, perceived social (p = 0.003) and motor (p < 0.0001) competence, global self-worth (p < 0.0001), BMI (p = 0.001), motor development (p < 0.0001), and engagement (p = 0.029). From pre-to-post intervention, children with obesity and overweight in the intervention group increased (1) playtime at home; (2) self-perceptions of social and motor competence and global worth; (4) engagement in the lessons, and improved scores, in motor skills; and (6) reduced BMI and screen time. The intervention promoted the health and improved the self-concept of children with obesity/ overweight.
Efficacy of AutoPulse for Mechanical Chest Compression in Patients with Shock-Resistant Ventricular Fibrillation
Authors: Gorący Jarosław , Stachowiak Paweł , Krejczy Arkadiusz , Piątek Patrycja , Gorący Iwona
Published: February 2022

Introduction: Sudden cardiac arrest is one of the most common causes of death. In cases of shock-resistant ventricular fibrillation, immediate transport of patients to the hospital is essential and made possible with use of devices for mechanical chest compression. Objectives: The efficacy of AutoPulse in patients with shock-resistant ventricular fibrillation was studied. Methods: This is a multicentre observational study on a population of 480,000, with 192 reported cases of out-of-hospital cardiac arrest. The study included patients with shock-resistant ventricular fibrillation defined as cardiac arrest secondary to ventricular fibrillation requiring ≥3 consecutive shocks. Eventually, 18 patients met the study criteria. Results: The mean duration of resuscitation was 48.4±43 min, 55% of patients were handed over to the laboratory while still in cardiac arrest, 83.3% of them underwent angiography and, in 93.3% of them, infarction was confirmed. Coronary intervention was continued during mechanical resuscitation in 50.0% of patients, 60% of patients survived the procedure, and 27.8% of the patients survived. Conclusions: Resistant ventricular fibrillation suggests high likelihood of a coronary component to the cardiac arrest. AutoPulse is helpful in conducting resuscitation, allowing the time to arrival at hospital to be reduced.