bluuebunny/crossref_metadata_2025 huggingface dataset:
Problematizar y deconstruir el concepto hegemónico de Política Exterior Feminista desde Abya Yala: hacia una propuesta de gradualidad en la implementación
Authors: Barbas Juan Martín , Chaves Dulce Daniela , Lucero Mariel Renée
Published: March 2022

Desde finales del 2014, tras el anuncio de Suecia de embarcarse en una Política Exterior Feminista (PEF), dicho concepto ha sido utilizado de forma amplia en ámbitos académicos y políticos, sin que se haya avanzado en la deconstrucción y delimitación del mismo, desde una mirada plural y crítica del feminismo. Las formulaciones teóricas existentes, provenientes casi todas de académicas/os estadounidenses y/o europeas/os, se limitan a registrar una serie de características mínimas y ambiguas, influenciadas por una lectura liberal y etnocéntrica de los feminismos. Esto permite que se utilice la noción de PEF para nombrar situaciones diversas, y que se establezca, al menos desde lo simbólico, un signo de igualdad entre casos que poco tienen en común; como pueden ser las políticas exteriores de Suecia, Canadá y México. Esta situación no resulta neutral, ya que, por un lado, le quita trascendencia y contundencia a las propuestas que desde hace décadas los feminismos vienen elaborando en materia de teoría de las Relaciones Internacionales; y por el otro, le permite a funcionarios/as, intelectuales y comunicadores/as, apropiarse y hacer un uso superficial de postulados feministas forjados al calor de las intensas luchas que las mujeres, y otros sectores feminizados, vienen llevando a cabo históricamente.
Frente a este panorama, resulta necesaria una disputa por el sentido que recupere los elementos más trasformadores de la tradición feminista. El abordaje utilizado en este trabajo es desde las perspectivas feministas críticas en Relaciones Internacionales. Primero, problematizamos algunas definiciones de política exterior feministas que circulan, y analizamos críticamente las autodenominadas políticas exteriores feministas de Suecia, Canadá y México, señalando falencias y contradicciones que las atraviesan. En una segunda instancia, procedemos a la elaboración de una definición de PEF que incorpora elementos provenientes de múltiples feminismos (decolonial, autónomo, negro, indígena), y que se asume explícitamente situada desde una perspectiva geográfica y cultural, subalternizada y contrahegemónica. Finalmente, proponemos una gradualidad en la categorización de aquellas políticas exteriores que empiezan a abandonar posicionamientos androcentristas y cisheteropatriarcales, a partir de la construcción de los conceptos de “Politica Exterior con Perspectiva de Género” (PEPG), y “Politica Exterior con Perspectiva de Género y Agenda Feminista” (PEGAF), cuyos significados y diferencias desarrollamos.
Pediatric low bone density: when to refer
Authors: Sukumaran Anju
Published: March 2022

Osteoporosis is a highly prevalent disease-causing high morbidity and health-care expenditures. As bone mass structure rarely varies from that of young adulthood, it is important for early recognition of low bone density disorders during childhood. This article will differentiate the common conditions causing low bone density and help Pediatricians promptly identify the patients in need of a Pediatric Endocrinologist referral by explaining the pathophysiology, evaluation, and management of these conditions.
From pregnancy to SARS Cov II- pandemia. “Like a bridge over troubled waters” COVID 19: a new virus- induced thrombotic microangiopathy model? LDH/AST ratio diagnostic role
Authors: Battini Lorella , Federica Mei , Francesca Egidi Maria , Fabrizio Caldi , Alessandra Bertolotto , Cristina Bianchi , Antonella Bertozzi Maria , Antonio Trojano Giuseppe , Pietro Bottone
Published: March 2022

Several scientific studies have shown that SARS-CoV II infection, responsible for the COVID 19 pandemic, can lead to a state of thrombotic microangiopathy (TM), both thrombotic thrombocytopenic purpura-like (TTP-like) and atypical hemolytic-uremic syndrome-like (aHUS-like), similarly to what occurs in the major thrombotic complications of pregnancy. The differential diagnosis between these disorders is very complex, due to overlapping clinical features, and also because they affect various disciplines. In the context of thrombotic microangiopathies, the test for the evaluation of ADAMTS-13 plays a key role, but in the pending or absence of the ADAMTS-13 test we can use PLASMIC score and /or LDH/AST ratio and these can help in the early stages of the disease. TTP and aHUS have different treatments: plasmapheresis in the TTP and Eculizumab in the aHUS. Therefore, we propose to the scientific community the LDH / AST score as a diagnostic aid, to help the differential diagnosis between the SARS-CoV II associated-TM and direct towards a more specific and effective therapy, in Covid-19 critical Patients.
KEBANGKITAN ISLAM PADA MASYARAKAT KONTEMPORER
Authors: Tasman Tasman
Published: March 2022

Perdebatan tentang agama dan sekularisme di dunia kotemporer telah menimbulkan diskusi panjang di kalangan ilmuan sosial dan agamawan. Kaum agamawan beranggapan bahwa paham sekularisme telah mengkudeta otoritas Ilahiah di muka bumi dengan kepongahan rasionalitasnya. Menurut mereka, rasio manusia  bersifat  liar, lemah  dan cenderung mengikuti hawa nafsu yang pada  akhirnya akan    mengancam keberadaan umat manusia. Karena itu, absolutisme agama menjadi niscaya untuk membuat manusia tunduk pada Tuhan. Sedangkan bagi pendukung sekularisme, manusia adalah makhluk yang bisa mengatur diri sendiri dan bisa berkembang ke arah liberalisme. Manusia harus bebas dari semua mitos supranatural. Pada tahap ini liberalisme mencurigai agama sebagai pendukung setia absolutisme kekuasaan atas nama agama. Pertanyaan penting dalam artikel ini adalah bagaimana masa depan agama pada masyarakat kontemporer? Menurut perspektif evolusi agama para ilmuwan sosial, agama cenderung akan mengalami kemunduran dan digantikan oleh rasionalitas dan sekulerisasi modern. Dengan munculnya industrialisasi, rasionalitas dan ilmu pengetahuan peran agama di dunia modern semakin memudar dan terpinggirkan. Sedangkan sebagian ilmuwan berpendapat bahwa modernitas berkembang bukan tanpa kritik, modernitas juga memiliki kelemahan-kelemahan mendasar yang memungkinkan manusia kembali kepada kehidupan keagamaan. Bahkan agama akan tetap eksis di dunia modern dalam bentuk yang sudah mengalami perubahan dan transformasi diri.
Adwa' al-Bayan Karya al-Shanqiti Sebagai Kitab Tafsir al-Qur’an bi al-Qur’an
Authors: Rohman Izza
Published: March 2022

This article examines the intensiveness, centrality and nature of inner-Quranic exegetical method – a method sometimes considered as providing more objectivity – employed by the Mauritanian-born exegete Muhammad al-Amin al-Shanqiti (19071973) in his Adwa’ al-Bayan. It compares the statistics of cross-referring of verses in this tafsir to that in other tafsirs known as also applying the method – in an attempt to show the level of its intensiveness. In addition, it also seeks to assess the centrality of this method in Adwa’al-Bayan by comparing statistical references to sources outside the Qur’an. In reviewing Adwa’al-Bayan’s style of interpreting al-Qur’an with al-Qur’an, this article looks at its application in the commentary of Sura Yasin.
Melacak Eksistensi Kosakata Mesir Kuno dalam Al-Qur'an
Authors: Laili Iffa Nurul
Published: March 2022

There has been a shift of paradigm between the classical Muslim scholars and the modern Muslim scholars in analyzing the Qur’an. The classical scholars preferred theological paradigm, while the modern scholars prefer academic and critical studies. In analyzing the Arabicity of Qur’anic language, the classical scholars argued that all language of the Qur’an are pure Arabic language. They based their argument on the verses of the Qur’an, and also on the theological view on the origin of Qur’anic language.  The modern scholars, on the other hand, argue for the existence of foreign words in the Qur’an. This view is based on the fact that the Qur’anic language is historical and cultural language, eventhough they do not deny its divine origin. In this article, the writer analyzes the view of Sa’d ‘Abd al-Mutallib al-‘Adl in his al-Hiruglifiyah Tufassir Al-Qur'an Sharh ma Yusamma bi al-Huruf al-Muqatta’ah which seeks to find the historical root of the Qur’an in Old Egyptian civilization to prove the use of Old Egyptian terms in the Qur’an.
Nalar Eksklusif Penafsiran Al-Qur’an Studi Terjemah Depag dan Tarjamah Tafsiriyah
Authors: Fadil Marjan
Published: March 2022

Artikel ini mengekplorasi nalar eksklusif maupun inklusif dalam penafsiran al-Qur’an dipengaruhi oleh rujukan tafsir, tujuan penafsiran serta ideologi penafsir. Hal ini berangkat dari langkah Depag serta Muhammad Thalib (pengarang Tarjamah Tafsiriyah) yang sama-sama memperjuangkan deradikalisasi pemahaman al-Qur’an. Namun, relatif berbeda dalam penerapan pada karya yang dihasilkan. Di sisi lain karya Tarjamah Tafsiriyah muncul sebagai langkah reaktif serta korektif terhadap karya Depag yang dianggap membawa pesan radikal. Akan tetapi kenyataannya Depag selalu memperjuangkan toleransi dalam kehidupan beragama di Indonesia. Melalui sudut pandang hermeneutika berbasis pendekatan sosio-historis ditemukan adanya bias dalam masing-masing karya tersebut dengan fokus pada ayat-ayat al-Qur’an bertemakan jihad dan relasi muslim dan non-muslim.
Nahdhatul Ulama and Muhammadiyah's Responses to the Religious Blasphemy in the Case of Non-Muslim Leader in Indonesia
Authors: Jannah Saadatul
Published: March 2022

This study aims to examine how the ideological preferences of Islamic organizations such as Nahdhatul Ulama (NU) and Muhammadiyah (MU) affect the understanding of the Quran. Using a descriptive analytic method, the author discusses how NU and MU respond to cases of blasphemy on the leadership of religion Indonesian non-Muslims. This article finds that understanding the Quranic text goes hand in hand with the understanding of the ideology of each organization. The performative function of the Quran will also work as it should depend on the understanding that has been established within an organization.
Lógicas simbólico-espaciales en procesos conflictivos de transformación urbana. Aproximación al caso Rosario, Argentina
Authors: Vera Paula
Published: March 2022

En esta presentación se propone avanzar en la comprensión del proceso de producción del espacio y los efectos sociales generados por las dinámicas de regeneración urbana, a partir del caso: “Transformación de la Ciudad Universitaria de Rosario y su entorno”. Partiendo de la teoría fenomenológica de los imaginarios sociales, el objetivo es identificar algunos elementos del entramado de sentidos donde se despliega este proceso. Para ello se implementa una estrategia metodológica cualitativa con enfoque socio-antropológico. Como resultado se presentan cuatro lógicas simbólico espaciales: visibilizar-invisibilizar, perder-ganar, abandonar-recuperar e imponer-disputar. Estas lógicas componen las matrices de sentido sobre las que se asientan los conflictos en torno de este proceso de transformación urbana.
Alexander Sima, Die sabäischen Inschriften aus Ẓafār: Aus dem nachgelassenen Manuskript herausgegeben von Norbert Nebes und Walter W. Müller
Authors: Geus Klaus
Published: March 2022

Review
Epistemic Modality in Amharic
Authors: Krzyżanowska Magdalena
Published: March 2022

Dissertation abstract
Conversation of Our Lord and Saviour Jesus with His Twelve Apostle Disciples at Jericho (EMML 7229, fols 93r–109r)
Authors: Getatchew Haile
Published: March 2022

The article presents a collation and translation of an apocalyptic text, which may be titled, Conversation of Our Lord and Saviour Jesus with His Twelve Apostle Disciples at Jericho, as taken from EMML 7229, fols 93r–109r. It is one of the two conversations known so far (the other took place at Däbrä Zäyt) and, although copied in the same hand, this conversation cannot be considered a part of the traditional Nägärä Maryam.
Caracterización química como línea base para una gestión de cuenca, Bahía Drake
Authors: Bolaños John Diego , Sancho Calvo Mayron
Published: March 2022

El artículo provee una línea base de conocimiento científico sobre iones cuantificados en cuerpos de agua dulce, en particular, de cinco ríos de la zona de Bahía Drake; esto para comprender los riesgos y vulnerabilidades del ecosistema, así como generar alertas en la protección del recurso hídrico. Se analizaron un total de 84 muestras representativas de los ríos Drake, Agujitas, Claro, Llorona y Sierpe, en tres campañas intensivas de muestreo, dos durante estación de verano y una en invierno, correspondientes a los años 2019 y 2020. Se determinaron los iones disueltos de cloruros, sulfatos, calcio, sodio, magnesio, potasio, zinc, plomo, cadmio, cobre, arsénico, manganeso y mercurio; para utilizarlos como indicadores de calidad ambiental y de salud humana. Los resultados destacan que la concentración de aniones en exceso proviene, principalmente, del impacto agropecuario en la zona de estudio, situación que es notoria en los ríos Drake, Llorona y Agujitas, en comparación con los ríos Claro y Sierpe; sin embargo, todos los ríos estudiados presentaron concentraciones iónicas de ríos sanos desde el punto vista químico, con una calidad aceptable una vez cotejados con la normativa nacional aplicable. La estación lluviosa mejora el equilibrio químico iónico de las sales disueltas en el agua, gracias al factor de dilución y a la capacidad de oxidación de la carga másica orgánica que transita sobre los ríos, lo cual favorece su oxigenación y acelera los procesos de depuración natural del río. Finalmente, no hay evidencia de metales pesados disueltos que favorezcan procesos de bioacumulación en los ecosistemas acuáticos estudiados.
Faktor Penentu Earning Per Share Perusahaan Properti dan Real Estate yang Terdaftar dalam Indeks Saham Syariah Indonesia
Authors: Ardinindya Gayatri Aisyah , Djuwarsa Tjetjep , Kusuma Dewi Rani Putri
Published: March 2022

In conducting this study, to determine the effect of the Current Ratio, Debt to Assets Ratio, Return on Assets to the Earning Per Share of property and real estate companies listed in ISSI. The sample in this study consisted of 12 property and real estate companies registered with ISSI. The data used was obtained from the official website of the Indonesia Stock Exchange, as well as the company's official website. The analytical method used is the panel data regression method using EViews 10 Software. The results obtained from this research are; CR partially positive and insignificant effect on EPS, DAR partially positive and not significant effect on EPS, ROA partially positive and significant effect on EPS, CR, DAR, and ROA simultaneously positive and significant effect on EPS.
Investigation of the sensitization rate for gibberellin-regulated protein in patients with Japanese cedar pollinosis
Authors: Mori Yuji , Okazaki Fumiko , Momma Keiko , Narita Hiroshi , Kondo Yasuto
Published: March 2022

Background: Pollen-food allergy syndrome (PFAS) usually manifests as an itching sensation in the mouth and throat immediately after eating fresh fruits and vegetables. However, some patients with PFAS experience systemic symptoms including anaphylaxis. In Europe, cypress gibberellin-regulated protein (GRP) has been noted to cause allergenicity and exhibit cross-reactivity with peach GRP. Japanese cedar (Cryptomeria japonica), classified in the cypress family, is the primary causative substance among all environmental allergens in Japan. However, studies on the prevalence of GRP sensitization in patients with cedar pollinosis are lacking.
Objective: This study examined the prevalence of GRP sensitization in patients with Japanese cedar pollinosis.
Methods: We enrolled 52 patients who had requested sublingual immunotherapy treatment with mild-to-severe rhinitis during spring, and had a JCP-specific immunoglobulin E (IgE) levels of >0.7 UA/mL. Peach GRP was purified using affinity chromatography with a monoclonal antibody column. Specific IgE levels to peach GRP were measured using an enzyme-linked immunosorbent assay. Samples exhibiting absorbance at 450 nm of over mean plus three standard deviations of the negative control value were defined as positive. Sera from three patients with severe peach allergy were used as positive controls.
Results: Eleven sera from 52 patients with JCP-induced allergic rhinitis were positive for peach GRP.
Conclusion: Twenty percent of patients with cedar pollinosis were sensitized to peach GRP. Well-powered studies are needed to clarify whether these patients are at an increased risk for systemic symptoms or whether they primarily demonstrate only localized symptoms.
Impact of allergic reactions and urticaria on mental health and quality of life
Authors: Stadler Pia-Charlotte , Marsela Enklajd , Kämmerer Till , Frommherz Leonie H. , Clanner-Engelshofen Benjamin , French Lars E. , Oppel Eva , Reinholz Markus
Published: March 2022

Background: Allergic diseases represent a major global health issue with more than one-third of the global population affected by at least one allergic condition. Allergic conditions can not only cause life-threatening anaphylactic reactions but also impact daily life with a significant influence on mental health and the quality of life (QoL).
Objectives: This study aims to evaluate the health-related QoL and depression severity among patients presenting in a tertiary care allergy center.
Methods: A cross-sectional study was conducted among 596 patients presenting with allergic symptoms or previously diagnosed allergies between October 2018 and April 2019.
Patients were screened for depression and the QoL impairment by using three validated scales: the Beck Depression Inventory (BDI), the Dermatologic Life Quality Index (DLQI), and the three-level version of the EuroQol 5-Dimensional (EQ-5D-3L) scale.
Results: One-third (34.8%) of the study population was male and two-thirds (65.2%) were female. About 73.7% (n = 427/579) of the patients suffered from at least one previously diagnosed allergic disease, most frequently to pollen (37.0%, n = 214/579) and food (27.3%, n = 158/579), and 20.0 % (n = 116/579) suffered from urticaria. About 19.3% of the total population suffered from depression. Urticaria, as well as insect venom, food/food additives, and drug allergies significantly affected the QoL and depression severity (p < 0.001), reflected by higher DLQI and BDI scores, and lower scores in the EQ5D-3L index.
Conclusion: Our results provide evidence for a possible correlation of allergies (e.g. against insect venom, food/food additives, and drugs) and/or urticaria with a reduced QoL and a higher depression rate. Patients particularly indicated restrictions for the dimensions, pain/discomfort as well as anxiety/depression. It might be beneficial to implement a standardized questionnaire as a regular screening method for evaluating the mental health status of patients with allergies and/or urticaria.
Local allergic rhinitis in children: A systematic review
Authors: Matsumoto Fausto Yoshio , Tranquillini Gonçalves Tessa Rachel , Solé Dirceu , Falbo Wandalsen Gustavo
Published: March 2022

Background: Local allergic rhinitis (LAR) is a well-defined and reported phenotype in adults, but data is scarce for children and adolescents, and it is probably an undiagnosed and highly underestimated condition in childhood.
Objectives: The objectives of this systematic review were to identify original observational studies published on LAR in children and adolescents and to describe the prevalence and characteristics of this phenotype in the pediatric age group.
Methods: A systematic search was performed in PubMed and EMBASE databases. The search was limited to publications on humans, written in English, published between January 1, 2000 and September 20, 2021. Participants had to be under 18 years old and with a diagnosis of LAR confirmed by nasal allergen provocation test (NAPT).
Results: Ten articles were identified. Despite the wide variability of protocols, prevalence rates ranged from 3.7 to 83.3% among children previously diagnosed as having nonallergic rhinitis, being markedly lower in Eastern countries (3.7–16.6%) when compared to Western countries (22.3–83.3%). To date, no relevant clinical characteristics capable of differentiating LAR patients from other childhood rhinitis phenotypes have been identified.
Conclusions: LAR is an allergic rhinitis phenotype also found in children. Population and regional differences and differences in NAPT protocols may explain the heterogeneity in LAR prevalence rates observed in different parts of the world. In addition to clarifying this large discrepancy, longitudinal studies are also needed to assess the clinical characteristics of the LAR phenotype in the pediatric age group, and its stability into adulthood must be confirmed.
Association between allergen component sensitisation and clinical allergic disease in children
Authors: Brand Paul L.P. , Brohet Richard M. , Schwantje Olof , Dikkeschei Lambert D.
Published: March 2022

Background: Allergen component sensitisation testing is becoming increasingly important in the diagnosis of peanut allergy. The aim of the present study was to evaluate the relationship between sensitisation and symptoms of allergic disease in children by testing a large panel of inhalants, food allergens, and allergen components.
Methods: For 287 children visiting our laboratory for allergy testing, symptoms of allergic disease were recorded by standardised validated questionnaires. Specific IgE to 11 whole allergens was assessed by ImmunoCAP, and to 112 allergen components by ISAC ImmunoCAP assay. We used latent class analysis (LCA) to distinguish clinical phenotypes.
Results: Inhalant and food allergen sensitisation was common, irrespective of the children’s allergic symptom type. Less than 10% of the variance in symptom scores was explained by variations in the number of allergens (components) that the child was sensitised to. In LCA, 135 children (50.2%) had mild allergy, with few symptoms and sensitisation to no or few allergens, 74 children (27.5%) had more symptoms and sensitisation to inhalant allergens (respiratory allergy) and 60 children (22.3%) showed polysensitisation to a median of six allergens and had more severe symptoms of different organ systems. Adding allergen component test results to LCA failed to result in identifiable classes of allergic disease in children.
Conclusions: In this group of children with allergic symptoms, referred for allergy testing by their physician, broad screening for allergen component sensitisation did not contribute to distinguishing phenotypes of allergic disease.
Non-Simultaneity and the Obligation to Its Dialectics (May 1932)
Authors: Bloch Ernst
Published: March 2022

The proposed translation of selected fragments of the work of the German philosopher Ernst Bloch “The Heritage of Our Times” is devoted to the temporal characteristics of various social groups of German society at the beginning of the 20th century. The first fundamental concept in these characteristics is the concept of non-simultaneity considered in different aspects. Second, it is the concept of heritage as a set of economic, political, cultural, mental elements of the past that remained in German society of the 1930s. Bloch showed the impact of these elements o on the life of the middle class (peasants, craftsmen, small-scale urban bourgeoisie). In Bloch’s view, the fact that the Nazis used these elements in their propaganda explains the popularity of Nazism in Germany. The author also forwards the characteristic of Germany as a classical state of non-simultaneity and poses the task to re-formulate the Marxist-style irrational in the mass consciousness and not to hand over dreams and images of the future to reactionary forces. Here Bloch makes use of the European philosophical tradition of Hegel and Marx. He introduces the concept of objectively non-simultaneous and subjectively non-simultaneous contradictions into the analysis of modern capitalism. Social dialectics, according to Bloch, should be multi-layered in the temporal aspect.
Factors Contributing to Depression in Community-Dwelling Older Adult during COVID-19: Using Data from the 2020 Community Health Survey
Authors: Jun Hye Jung , Jeong Yeon Jin
Published: March 2022

Purpose: The purpose of this study was to examine the correlations among perceived health status, stress, daily life changes, physical distancing, depression, and to determine associated fctors of depression fo older adults in COVID-19.Methods: This study was conducted on 42,448 persons aged 65 years and above who participated in the 2020 Community Health Survey Data analysis was done with SAS 9.4.Results: The factors related to depression of community-dwelling older adults were gender (β=.04, p<.001), age (β=.07, p<.001), education (β=-.04, p<.001), monthly household income (β=-.02, p<.001), depressive symptoms (β=.27, p<.001), unmet healthcare needs (β=-.08, p<.001), households (β=.02, p<.001), perceived health status (β=.21, p<.001), stress (β=-.26, p<.001), daily life changes (β=-.03, p<.001), and physical distancing (β=-.02, p<.001). The descriptive power of this regression model was 31%.Conclusion: Treatment and education for diseases and depression should be provided to community-dwelling older adults to prevent and manage their depression. In particular, nursing interventions are needed to improve depression in the older adults. Health care programs such as reducing stress and maintaining daily activities while maintaining good health should also be provided.
Leopard preyed on Jungle cat: evidence from the mid-hill of Nepal
Authors: Bhandari Shivish , Baral Kedar , Adhikari Binaya
Published: March 2022

In the pictures taken by the camera trap, the photo of a leopard hunting a jungle cat is rare. This type of evidence makes it easier to understand the current status of wildlife and also implement further conservation actions. This study was conducted from November 2020 to December 2020 in the mid-hill regions of Nepal. We installed the camera traps in l*1 km grid cell covering about 60 km2. Out of 36 camera trap locations, 1 leopard preying on a jungle cat was captured in one location. Our study concluded that carnivores could capture another sympatric family because of the lack of natural prey species. Therefore, conservation of the natural prey species including small carnivores or mammals is also essential to conserve the leopard population.
Some remarks on a German chipped stone lithic assemblage of uncertain origin in the collection of the Institue of Archaeological Sciences, Eötvös Loránd University
Authors: Péntek Attila , Faragó Norbert
Published: March 2022

András Marton has recently come into the possession of a small, chipped stone assemblage from the legacy of a German amateur mineral collector from Hamburg. Unfortunately, very little is known about the deceased and his collection. A part of the finds, including tools, was donated to the Institute of Archaeology of the Eötvös Loránd University. The lithic assemblage contains a total of 27 chipped stone artefacts made exclusively of Baltic flint. Concerning the raw material used, these flint varieties with the banded structure are rather unusual in Schleswig-Holstein. They are much more likely to originate from Lower Saxony or perhaps Mecklenburg-Western Pomerania. Apart from the general technological description of the assemblage, some pieces from these non-formal tools have been selected for a detailed description. The application of the “direct percussion with a hard hammer” technique and the presence of the thick artefacts contradict the Palaeolithic or Mesolithic origin of the assemblage, except for the flint axe (“Kernbeil”), which has a possible Mesolithic association. Alternatively, if the edges of the artefacts are not worn out or rolled, then along the edges of all artefacts traces of some kind of “cryoturbation retouch” are observable. In this case, the Palaeolithic dating of the finds is more plausible.
Thiersch graft follow-up with narrow band imaging for Acquired atresia of the external auditory canal: Canaloplasty with thiersch graft vs vascularization evaluated with narrow band imaging
Authors: Pace Annalisa , Rossetti Valeria , Visconti Irene Claudia , Milani Alessandro , Iannella Giannicola , Maniaci Antonino , Cocuzza Salvatore , Magliulo Giuseppe
Published: March 2022

Acquired atresia of the external ear canal is a narrowing of the external ear canal (EAC) that appears obstructed by fibrous tissue or bone tissue. Acquired atresia has two different phases: wet and dry stage. Computed tomography (CT) scan may show a scan where soft tissue fills EAC. Treatment may be medical and/or surgical. The surgical treatment of choice is represented by canaloplasty with a skin-free flap. To our knowledge, no article has reported data on the analysis of vascularization of acquired atresia of the external ear canal and vascularization of skin flap during follow-up with narrow-band imaging. This study evaluated patients suffering from acquired atresia of the external auditory duct, treated surgically in our Department of Organi di Senso of Sapienza University, from 2017 to 2020. All patients underwent: anamnestic collection, physical examination, CT. Preoperative and postoperative otoendoscopic evaluation (1,3,6 and12 months) was performed with both cold white light endoscopic vision (CWL) and narrowband imaging (NBI). 17 patients were enrolled in the study. Preoperative otoendoscopic examination of WL showed stenosis with a diameter <75% and a tympanic membrane not viewable in all patients. At 12 months of follow-up, 94% of patients had no recurrence of external ear canal stenosis. 88% of patients had normal NBI light vascularization. Our study evaluated how NBI can be a superior method, compared to CWL, to assess the state of the flap and can be relevant in the decision-making process of a re-intervention.
Együttműködések fenntarthatósága a határ mentén: egy szlovén-magyar turisztikai kezdeményezés esetleírása és elemzése
Authors: Tóth-Kaszás Nikoletta , Keller Krisztina , Péter Erzsébet , Lelkóné Tollár Ildikó , Németh Kornél
Published: March 2022

A 21. század turistáinak fogyasztói magatartását vizsgálva azt tapasztaljuk, hogy a látogatókat már nem az egyes szolgáltatások, hanem a komplex élmények érdeklik. Ebből adódóan a földrajzi alapú, desztinációs logika elengedhetetlenné vált a megfelelő élménykínálat kialakításához. A turizmusban a térségi alapon szerveződő együttműködéseknek évtizedes hagyománya van, amely a turisztikai desztináció menedzsment (TDM) logikában csúcsosodott ki. Tanulmányunkban egy ilyen együttműködés keretében megvalósuló turisztikai kezdeményezést mutatunk be, amelynek további sajátossága, hogy egy magyar és szlovén partnerek által létrehozott, határon átnyúló koncepció alapján jött létre. A kezdeményezés és a projekt tematikáját a mesék világ köré építették a partnerek, elsősorban tematikus parkok (Meseparkok) kialakításával és rendezvények megvalósításával. A Meseparkok és az együttműködés fenntarthatóságának kérdései azonban már a kezdetektől kihívás elé állítják a partnereket.
Tanulmányunk szakirodalmi áttekintéssel kezdődik, melynek keretében röviden felvázoljuk a változó turisztikai fogyasztói szokásokat, a turisztikai együttműködések kihívásait, különös tekintettel a tematikus parkokra és fenntartásuk problémáira. Emellett röviden bemutatjuk a tanulmány középpontjában álló projekt által lefedett területet is.
Tanulmányunk elemző része a kínálati oldalon végzett empirikus kutatási eredményekre épül, a vizsgálatot a projektpartnerek körében végeztük strukturált interjúk segítségével. Az elemzésben a 2019 nyarán és ősz elején a projekt keretében létrehozott meseparkok területén és a rendezvények alkalmával folytatott kérdőíves vizsgálat néhány eredményét is felhasználtuk. Tanulmányunk az interjúk, a kérdőíves felmérés tapasztalatai, valamint a szakirodalom releváns forrásai alapján olyan javaslatokat fogalmaz meg, amelyeket nélkülözhetetlennek tartunk egy határon átnyúló turisztikai együttműködés fenntarthatóságához.
Influência do primeiro desbaste no crescimento de quatro espécies do gênero Pinus
Authors: Nicoletti Marcos Felipe , Lambert Luciano , Soares Philipe Ricardo Casemiro , Cruz Girlene da Silva , Almeida Bruno Rafael Silva de
Published: March 2022

O objetivo deste estudo foi quantificar e comparar a influência do primeiro desbaste nas variáveis dendrométricas de quatro espécies de Pinus spp. no Estado de Santa Catarina. Os povoamentos monitorados comtemplaram as seguintes espécies: Pinus elliottii Engelm var. elliottii, Pinus greggii Engelm, Pinus taeda L., Pinus patula Schlechtd. & Cham. Os dados foram obtidos por meio de censo florestal e análise de tronco completa por classes diamétricas selecionadas pelo método de Sturges. Foram coletados seis discos por árvore nas alturas absolutas de 0,1 e 1,3 m e, também, nas alturas relativas de 25%, 50%, 75% e 100% da altura comercial e diâmetro igual a 8 cm. Para a distribuição diamétrica foi verificada a normalidade dos dados pelo teste de Shapiro-Wilk. As taxas de crescimento da largura dos anéis dos dois anos que antecedem o desbaste nas alturas de 0,1 m, 1,3 m e 25% reduzem para todas as espécies. Nas alturas de 50% e 75% a taxa de crescimento tende a se estabilizar para o mesmo período, com exceção do Pinus elliottii. Em 100% da altura comercial, Pinus elliottii apresentou crescimento superior ao Pinus taeda, aproximadamente, 50% ao comparar. O efeito do desbaste tardio, entre as árvores, teve influência no crescimento para as diferentes espécies estudadas.
Normatização do teste de função Manual Jebsen-Taylor para população brasileira
Authors: Negrão Christian Guimarães Cilento , Rufino Larissa Albuquerque , Souza Aline Bernardes de , Cymrot Raquel , Blascovi-Assis Silvana Maria
Published: March 2022

O objetivo deste estudo foi apresentar dados normativos para o TFMJT para a população brasileira. Participaram do estudo 360 pessoas, entre 06 e 49 anos, divididas em seis grupos por faixa etária, sendo 178 do sexo masculino e 182 do sexo feminino. Os dados foram apresentados separadamente para as diferentes faixas etárias, para sexo masculino e feminino. Os valores referentes às médias e ao desvio padrão foram calculados para cada uma das sete tarefas, considerando mão dominante e mão não dominante. Observou-se desempenho superior para mão dominante, com diferença significante para a soma das sete tarefas, em ambos os sexos (p=0,001). Os resultados obtidos poderão servir de parâmetros de referência para a população brasileira e contribuir para avaliações quantitativas do desempenho manual em programas de avaliação ou reabilitação do membro superior.
Intervenção interdisciplinar reduz o consumo de alimentos ultraprocessados em adolescentes com sobrepeso ou obesidade
Authors: Walker Marthina Streda , Andrades Clara dos Santos de , Richrot Thamy Schossler , Closs Vera Elizabeth , Gustavo Andreia da Silva , Oliveira Margareth da Silva , Donadio Márcio Vinícius Fagundes , Feoli Ana Maria Pandolfo
Published: March 2022

Este estudo objetivou avaliar o efeito da intervenção interdisciplinar com abordagem motivacional sobre o consumo de alimentos ultraprocessados em adolescentes com sobrepeso ou obesidade. O método utilizado foi um ensaio clínico randomizado no qual os participantes distribuíram-se em grupo controle (GC) e grupo intervenção (GI). A coleta de dados do consumo alimentar ocorreu mediante o recordatório de 24 horas, obtido no início e ao final das intervenções. Os alimentos consumidos foram categorizados nos quatro grupos da classificação alimentar NOVA conforme o grau de processamento a qual são submetidos. Participaram 42 adolescentes com média de idade de 16,5±1,3 anos, a maioria do gênero feminino (69%). No GI, a média de quilocalorias de alimentos ultraprocessados diminuiu 37,5% após a intervenção; em contrapartida, aumentou o consumo de alimentos processados em ambos os grupos. Concluiu-se que a intervenção interdisciplinar com abordagem motivacional foi eficaz na redução do consumo de alimentos ultraprocessados na população estudada.
Evidências de validação de um instrumento de avaliação do apoio social a hipertensos por profissionais da atenção básica
Authors: Paes Neir Antunes , Farias Dyego Anderson Alves de , Leite José Carlos de Lacerda
Published: March 2022

Este trabalho objetivou propor e verificar evidências de validação de um instrumento de avaliação do apoio social ao hipertenso na perspectiva de profissionais prestadores de serviço na Atenção Básica. Para o percurso metodológico, realizaram-se as etapas: consulta a especialistas, imputação de dados e análise fatorial confirmatória (AFC). O instrumento proposto foi adaptado do Primary Care Assessment Tool versão profissionais, sendo validados seis itens agregados nas dimensões conceituais “Enfoque na família” e “Orientação para a comunidade”, que foram confirmados pela AFC com base no ajuste do modelo (CNIN/DF = 2,256; RFI = 0,924; NFI = 0,959; IFI = 0,977; TLI = 0,956; e CFI =0,977). Evidenciou-se uma correlação significativa (p-valor = 0,000) e positiva entre as dimensões. A adequada consistência interna e confiabilidade no ajuste do modelo permitiu a reprodução dele respeitando-se as limitações. Assim, disponibiliza-se aos gestores e pesquisadores um instrumento estatisticamente validado para avaliar o apoio social aos hipertensos.
Effect of manual therapies on cardiac autonomic control: a systematic review
Authors: Sousa Kamila Aparecida de , Cardoso Leila Batista , Pirola Flavia Maria , Auad Luciana Gonzalez , De Oliveira Adriana Sarmento
Published: March 2022

Background: Evidences suggest that manual therapies, a physiotherapy specialty widely used in the treatment of musculoskeletal disorders, would be complementary or alternative for the treatment of cardiac autonomic dysfunction present in the elderly, patients with cardiovascular diseases, some neuromuscular diseases and in some pain processes. Objective: Evaluate the available scientific evidence regarding the effect of manual therapy techniques on cardiac autonomic control. Methods: The selected articles were indexed in the databases PubMed/MEDLINE, SCIELO and LILACS. Results: In the initial search, 233 articles were identified in the electronic databases. After initial analysis of the titles, 210 articles were excluded because they did not address the research topic, performed other types of intervention or evaluation or because they were review articles. A second step of evaluating the 23 previously selected articles was carried out and consisted of reading the abstracts of the articles. After reading the abstracts, 11 were selected. According to the analysis of the selected articles, it was possible to observe that most manual therapy techniques improved the cardiac autonomic control of their samples: Fornari, Carnevali and Sgoifo (2017), Girsberger et al. (2014), Valenzuela et al. (2018), Curi et al. (2017), Akbaş et al. (2019), Buttagat et al. (2009),Kunikata et al. (2012), Mantovani et al. (2005) and Giles et al. (2011). Guilherme et al. (2010) was the only study that found no change. Conclusion: Manual therapies have improved cardiac autonomy acutely in healthy young and middle-aged populations or with discomfort, hypertension and back pain associated with the presence of myofascial trigger points. It is emphasized the importance of conducting new randomized controlled studies, with high methodological quality, that address the effect of other manual therapies on cardiac autonomic control.
Proteomic Profiling of the Oncogenic Septin 9 Reveals Isoform-Specific Interactions and Functions in Breast Cancer Cells
Authors:   , Devlin Louis Joseph , Spiliotis Elias T
Published: March 2022

Proteins in cells do not act in isolation and septins are no exception. Septins associate with other septins and non-septin biomolecular partners to impart their influence on myriad of dynamic cellular processes such as the cell cycle and structures such as the cytoskeleton. Though several studies probing the interactome of septin 9 (SEPT9) have been performed, little is known about the molecular interactions and pathways of SEPT9 isoforms, and how they contribute to the development and metastasis of breast cancer. In Chapter 1, I provided a comprehensive review of SEPT9, an essential and ubiquitously expressed septin with multiple isoforms and altered expression in breast cancer and other diseases including neurological disorders. In Chapter 2, we investigated isoform-specific molecular interactions of SEPT9. Using comparative shotgun proteomics, we identified and mapped the interactomes of SEPT9 isoforms 1, 4 and 5 into spatial and functional networks and subnetworks. We revealed isoform-specific interactions with proteins of distinct subcellular localizations and functions, implicating SEPT9 isoforms in hitherto unknown mechanisms of tumorigenesis. We hypothesized that truncations in the N-terminal sequences of SEPT9 isoforms bestow a functional specialization by biasing toward specific septin and non- septin binding partners. Our results provide rare evidence for septin isoform-specific interactions, which can benefit future work on the oncogenic functions and therapeutic targeting of SEPT9. Finally, in Chapter 3, I explored the challenges, considerations and lessons learned when embarking on a proteomics project to identify protein interaction partners. This chapter includes a critical appraisal of the methodologies.
Relationship between temperature, temperature-humidity index and amount of food intake of Sheep
Authors: Loi Bui Van , Ba Nguyen Xuan , Ngoan Le Duc , Linh Nguyen Quang
Published: March 2022

This study aimed to identify the relationship between temperature, temperature-humidity index (THI), and the amount of dry matter food intake (DMI) by sheep. Twelve Phan Rang (Ninh Thuan province) sheep belonging to three age groups of 6, 9, and 12 months (4 heads of each age group) raised in Thua Thien Hue province were fed with natural grass for two seasons: hot season (April-August) and cold season (November-February). Daily temperature, humidity, and food intake were recorded. The results of the study revealed that temperature and THI were closely correlated (P<0.05) with the amount of food intake by sheep. When the temperature was in the range of 29.5°C to 32.5°C and increased by 1ο C, the DMI of sheep decreased by 14.7 g/BW/day. When the value of THI was more than 28.5 and rose by 1°C, the DMI of sheep decreased by 16.2 g/BW/day.
Evaluation of haematological and behavioural changes in Channa punctatus (Bloch) on short-term exposure to a commercial-grade synthetic pyrethroid pesticide
Authors: Ghosh Pratyush , Das Enakshi , Ghosh Arka
Published: March 2022

This study aims to assess the acute toxicity of commercial-grade Cypermethrin (10% EC) and evaluate the hematological and behavioral alterations in a freshwater fish Channa punctatus upon short-term exposure to Cypermethrin. A four-day static acute toxicity test was performed to estimate the median lethal concentration (LC50) value of Cypermethrin. During the acute toxicity test, the behavior of the control and cypermethrin exposed fish was critically observed and recorded. After completing the acute toxicity test, the hematological effects of Cypermethrin in C. punctatus were evaluated using two sublethal dosages (0.08 mg/L and 0.12 mg/L). Results of the study revealed that this pesticide induced significant mortality in C. punctatus with a 96-h L50 value of 0.263 mg/L. Cypermethrin exposed fish showed hyperactivity, irritability, erratic swimming, frequent surface visit, etc. Exposure to sublethal concentrations of Cypermethrin for a short period resulted in a significant decline (P<0.05) in total erythrocytes count (TEC), packed cell volume (PCV), mean corpuscular volume (MCV), and hemoglobin (Hb) concentration as compared to control groups. In contrast, pesticide-exposed groups had a significant increase (P<0.05) in mean corpuscular hemoglobin concentration (MCHC) and total leucocyte count (TLC). It is apparent from the results of the study that this commercial formulation is toxic to the studied fish. This study also revealed hematological and behavioral alterations in C. Punctatus which could be used as biomarkers for incipient Cypermethrin intoxication.
Rapid Biosynthesis of Silver Nanoparticles by Celtis tournefortii LAM. Leaf Extract; Investigation of Antimicrobial and Anticancer Activities
Authors: BARAN Ayşe , KESKİN Cumali , İRTEGÜN KANDEMİR Sevgi
Published: March 2022

The usage of metallic nanoparticles are very common. Environmentally friendly approaches in obtaining nanoparticles attract a lot of attention because of their advantages. In this study, an easy and economical biosynthesis of silver nanoparticles (AgNPs) was made with the extract of Celtis tournefortii LAM. leaf. For the characterization of synthesized nanoparticles, Spectrophotometer (UV-vis), Transmission Electron Microscope (TEM), Field Emission Scan Electron Microscopy (FE-SEM), Atomic Power Microscopy (AFM), Electron Disperse X-ray (EDX) Fourier Transformation Infrared Spectroscopy (FT-IR), X-ray Diffraction (XRD), Thermogravimetric and Differential Thermal Analysis (TGA-DTA), Zeta Sizer and Zeta Potential Analysis data were used. As a result of the data analysis, it was determined that the AgNPs had a spherical appearance, an average size distribution of 4.8 nm, had a maximum absorbance at a wavelength of 482.13 nm, a crystal nanosize of 10.95 nm, and a surface charge of -21.6 mV. Inhibition activities of AgNPs on the growth of pathogenic strains were determined by the microdilution method. The results showed that the nanoparticles were effective even at low concentrations. The Minimum Inhibitory Concentration (MIC) value of the tested materials on the growth of the strains was found between 0.03-1.00 µg mL-1. Anticancer activity of AgNPs was investigated on CaCo-2, U118, Skov3 cancer cell lines and healthy cell line HDF by the MTT method.
Tourism and third sector organisations: synergies for responsible tourism development?
Authors:   School of Management, Hospitality and Tourism, Universidade do Algarve, Portugal, Martins Paula Guerreiro , Ferreira Ana Maria Alves ,   School of Social Sciences, University of Évora, Portugal, Costa Carlos ,   Department of Economics, Management, Industrial Engineering and Tourism, Research Unit of Governance, Competitiveness and Public Policies (GOVCOPP), University of Aveiro, Portugal
Published: March 2022

The main aim of this paper is the analysis of the third sector arts, culture and local development organisations (TSO) participation in the context of tourism planning and development and to understand the characteristics of its connections to the tourism sector in the region of the Algarve. The methodological strategy is anchored in a mix-methods approach applying qualitative techniques such as semistructured interviews (n=40), document analysis, non-participant observation, and adopting a triangulation approach. There have been few empirical studies that analyse this theme, thus, identifying the forms of participation that the third sector can adopt and their characteristics constitutes one of the main contributions of this research towards reinforcing the conceptual framework in the context of responsible tourism development. The results revealed that third sector organisations display a set of characteristics that position them as active agents in the tourist planning and development processes by operating on areas such as the promotion of cultural expression, research and inventory of cultural and natural resources, raising awareness of those resources and also by actively participating in supply structuring of tourist services.