bluuebunny/crossref_metadata_2025 huggingface dataset:
El “clima eclesial” de la recepción latinoamericana del Vaticano II como trasfondo del pensamiento del papa Francisco
Authors: Polanco Rodrigo
Published: April 2023

El artículo revisa literatura teológico-pastoral latinoamericana, de entre los años 1965 y 1968, a fin de percibir el modo particular como en Latinoamérica se recibió el Concilio Vaticano II. Se percibe así un cierto “clima eclesial”, que entiende que el proceso conciliar no ha terminado, lo cual invita a un cambio de mentalidad que debe articularse en estructuras nuevas que permitan la participación de todos en la responsabilidad y misión de la Iglesia. Conocer este “ecosistema eclesial y pastoral” del que bebió Francisco en sus primeros años, permite entender las orientaciones que el proceso sinodal está entregando.
The Effect of Changes in the Radio-Ulnar Angle on Wrist Scores on the Treatment of Intra-Articular Fractures of the Distal Radius with Wrist Fixator
Authors: AKAR Bedrettin , YÜCEL Mücahid Osman
Published: April 2023

Aim: This study was aimed to evaluate the effect of radial inclination (RI) angle, assessed with radiological measurement, on the clinical outcomes of intra-articular fractures of the distal radius (IFDR) treated with closed reduction and penning type dynamic wrist fixator.
Material and Methods: A total of 120 patients who underwent closed reduction and dynamic wrist fixation due to IFDR between 2012 and 2020 were retrospectively reviewed. The effects of the changes in RI on clinical outcomes according to Mayo wrist scoring (MWS) criteria were investigated by measuring the RI angles in anteroposterior wrist radiographs of the patients at postoperative 2nd, 6th, and 10th weeks.
Results: According to the AO fracture classification, 77 (64.2%) of the patients had type C1 and 43 (35.8%) of the patients had type C2 fracture. The patients comprised 69 (57.7%) females and 51 (42.3%) males, and the mean age was 50.08±15.36 years. Fixators were removed at six weeks. RI angles measured at post-op week 10 were 20°-30° in 83 (69.1%) patients, 10°-19° in 32 (26.6%) patients, and 0°-9° in 5 (4.3%) patients. According to MWS, 39 (32.5%) patients were evaluated as excellent, 76 (63.3%) patients as good, and 5 (4.2%) patients as moderate. A statistically significant positive correlation was observed between RI values and MWS (r=0.369, p<0.001).
Conclusion: Dynamic wrist fixation with closed reduction is a simple and minimally invasive method, and provides successful clinical and functional results in the treatment of IFDR. We consider that optimal RI angles are effective in clinical and functional outcomes.
Comparative characteristics of methods for formation of pharyngo-esophageal anastomosis and tubeless tracheostomy in laryngectomized patients
Authors:   National Medical Research Center for Otorhinolaryngology  of the Federal Medico-Biological Agency of Russia, Moscow, 123182, Russia, Daikhes N. A. , Vinogradov V. V. ,   National Medical Research Center for Otorhinolaryngology  of the Federal Medico-Biological Agency of Russia, Moscow, 123182, Russia, Reshul’skii S. S. ,   National Medical Research Center for Otorhinolaryngology  of the Federal Medico-Biological Agency of Russia, Moscow, 123182, Russia, Fedorova E. B. ,   National Medical Research Center for Otorhinolaryngology  of the Federal Medico-Biological Agency of Russia, Moscow, 123182, Russia, Isaeva M. L. ,   National Medical Research Center for Otorhinolaryngology  of the Federal Medico-Biological Agency of Russia, Moscow, 123182, Russia
Published: April 2023

Radical treatment of laryngeal cancer allows achieving good oncological results but leads to disability of patients. Restoration of voice function after laryngectomy is the main aspect of rehabilitation. The improvement of existing methods of pharyngeal reconstruction contributes to the creation of favorable conditions for subsequent rehabilitation. Objective. Improving the effectiveness of the results of the surgical stage of complex rehabilitation of laryngectomized patients. Materials and methods. The results of surgical treatment were analyzed in 70 patients diagnosed with stage III–IV laryngeal cancer. Patients were divided into 2 groups depending on the technique of suturing the pharynx and the formation of a tubeless tracheostomy. Results. The developed technique of pharyngeal reconstruction with simultaneous formation of anatomical and physiological prerequisites for early rehabilitation of patients after laryngectomy does not increase the total operation time and averages 25–30 minutes in 68.57% of cases, reduces the likelihood of complications in the postoperative period by 11.41%, reduces the incidence of scarring deformities of the pharyngeal-esophageal funnel by 11.43%, allows achieving the formation of a tubeless tracheostomy resistant to narrowing in 74.27%, and does not affect the oncological effectiveness of combined treatment of patients with stage III–IV laryngeal cancer. Conclusion. The developed method of closing the pharyngeal defect after laryngectomy showed high effectiveness and allowed improving the results of postoperative wound healing, reducing the number of local postoperative complications as well as improving functional results.
State of auditory function of children in orphanages evacuated from war zone
Authors:   Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013, Russia, Levin S. V.
Published: April 2023

In this study, the structure and frequency of hearing impairment in children who lived at various times in the territories of military operations were studied. The high prevalence of otorhinolaryngological diseases, combined with low detectability, entails formidable complications, leads to a decrease in the quality of life of the child and the family as a whole, and negatively affects the general level of public health. In total, during the study, 398 children aged 5 to 16 years old were examined, who were in the temporary accommodation center of the Romashka children’s resting camp. The children are students of orphanages in the Donetsk People’s Republic (DPR) and the Luhansk People’s Republic (LPR) evacuated from the war zone in the first days of the Special Operation. There were 216 girls (54.3%) and 182 boys (45.7%) among them. The average age of children was 8.5 years. Hearing loss was detected in 33 children (8.3%). Two children (0.5%) had a severe form of sensorineural hearing loss of 3–4 degrees. Two children (0.5%) had a mild form of sensorineural hearing loss of 1–2 degrees. Four children (1%) had unilateral chronic sensorineural hearing loss. The diagnosis of otitis media with effusion was established in 20 children (5%), tubo-otitis, in three patients (0.8%). Suspicion of an anomaly in the development of the middle ear, in 2 children (0.5%). Examination of children in orphanages evacuated from the DPR and LPR did not reveal a high prevalence of hearing impairment. Sensoneural hearing loss: 2%, conductive hearing loss: 6.3%. The results of the work demonstrate a wide potential for improving hearing health in the examined children. Active diagnostics of hearing pathology is shown to all children in orphanages. After treatment of conductive hearing pathology, mandatory audiological monitoring is indicated, despite the subjective improvement in hearing.
The orbital complications of acute rhinosinusitis in pediatric patients: observational study
Authors:   Samarkand State Medical University, Samarkand, 140100, Uzbekistan, Ulashev Sh. M. , Makhmudova S. K. ,   Samarkand State Medical University, Samarkand, 140100, Uzbekistan, Khushvakova N. Zh. ,   Samarkand State Medical University, Samarkand, 140100, Uzbekistan
Published: April 2023

Objectives. To describe the experience of orbital complications of ARS in the paediatric population and to identify risk factors associated with disease severity. Methods: This retrospective analysis evaluated the clinical outcomes of 78 children hospitalised for orbital complications between 2005 and 2020. Descriptive statistics were used to examine demographic data and clinical symptoms. Results. Although all children were treated with antibiotics prior to hospitalisation, more than half of this cohort experienced post-septal orbital complications. A significant association was found between age at admission and severity of illness. Children over seven years of age had more severe orbital complications and were more likely to require surgery despite the administration of antibiotics prior to hospitalisation (p < 0.001). Conclusions. In this study, stage II and III orbital complications at admission and older age were the most important determinants of failure of medical treatment. Early referral to an otolaryngologist should be considered for children older than seven years with ORS, as more severe orbital complications may occur despite preclinical antibiotics.
Case report of rhinogenic orbital complication
Authors:   Surgut Regional Clinical Hospital, Surgut, 628408, Russia, Moskalev V. A. , Okasov R. R. ,   Surgut Regional Clinical Hospital, Surgut, 628408, Russia, Chinarev D. S. ,   Surgut Regional Clinical Hospital, Surgut, 628408, Russia
Published: April 2023

The article discusses a clinical case of such a rather formidable rhinogenic intraorbital complication as orbital cellulitis against the background of stomatogenic sinusitis. The presented clinical case of successful treatment of a patient demonstrates how the correctly chosen treatment tactics and timely surgical treatment contributed to the preservation of not only vision but also the patient’s life. Objective. To show a clinical observation of the development of orbital complications against the background of chronic apical periodontitis. Materials and methods. The evaluation of the results of the study, including video endoscopy of the nasal cavity, CT scan of the paranasal sinuses, was carried out. Data were obtained on the prevalence of the process that caused not only the inflammatory process in the paranasal sinuses but also the destruction of the medial and upper bone walls of the right maxillary sinus with the formation of an inflammatory infiltrate in the retrobulbar space. Access to the maxillary sinus was discussed, the patient was consulted by an ophthalmologist, maxillofacial surgeon, and surgical intervention was performed.
Опыт диагностики и лечения пациентки с осложнениями хронического тонзиллита
Authors:   Сlinical Hospital N 1 of Presidents Administration of Russian Federation, 121352, Moscow, Russia, Pelishenko T. G. , Lazarchik T. A. ,   Сlinical Hospital N 1 of Presidents Administration of Russian Federation, 121352, Moscow, Russia
Published: April 2023

The article presents a clinical case of one of the complications of chronic tonsillitis, which required differential diagnosis. The clinical picture is displayed, starting from the onset of the disease, the results of laboratory and instrumental methods of research are presented, on the basis of which a diagnosis was made. The results of pathohistological examination are presented.
Computational study of the hovercraft hydraulic transmission
Authors: Sosnovsky N.G. , Nguyen Van Hoa
Published: April 2023

Implementation of the vehicles optimal operating modes and improvement of their energy efficiency appears to be an urgent task. The paper considers a hovercraft with the hydraulic transmission. Combined mathematical model of hydraulic transmission and fan supplying air to the air cushion section was developed. Automatic control of the pump swashplate inclination angle with the vessel moving upon different support surfaces was analyzed in the MATLAB/Simulink environment in terms of increasing efficiency of the fan and system operation. The system calculation scheme is presented, and acceptable transient characteristics were obtained. The developed mathematical model makes it possible to select and assess optimal frequency of the hydraulic motor shaft rotation with the vessel moving upon different surfaces, analyze and improve the system energy efficiency. Using the proposed transmission control unit in a hovercraft allows maintaining the fan efficiency and the required vessel height above the supporting surface.
Research on the synthesis of bionic thin-walled structures of the aircraft fuselage compartment type
Authors: Zheleznov L.P. , Laperdina N.A.
Published: April 2023

The topological optimization method was used to synthesize bionic structures for the promising small aircraft compartment made of aluminum alloy. Topological optimization was performed on the basis of the ESO-SIMP method using the ANSYS Workbench software tools. Influence of the design parameters, in particular, of the shell thickness, on the strength and weight characteristics of the compartment bionic structures after topological optimization was studied under the external loads action.
Real-time three dimensional tte in quantification of left ventricular dyssynchrony
Authors: Mamedova A. I. , Prihod’ko N. A. , Lubimceva T. A. , Kozlenok A. V. , Lebedev D. S.
Published: April 2023

Background. The main problem in the patient selection for cardiac resynchronization therapy (CRT) is the lack of unified approaches to the definition of mechanical dyssynchrony (MD) and selection criteria.

Objective. To reveal the dependence of the criteria of dyssynchrony in patients on the method and point of stimulation and to reveal the correlation of these data with the width of the QRS complex and the percentage of global two-dimensional longitudinal deformation.

Design and methods. The study involved 12 patients with drug-compensated CHF of class II-IV, LVEF< 35 % and a QRS duration >130 ms, having CRT indications. All patients were intraoperatively injected with a retrograde transaortically guided electrode. During stimulation of each point (88 points), transesophageal Echo-KG (PE Echo-KG) was performed. TomTec and Philips Qlab 3DQ Advanced software was used for data analysis.

Results. The segmental excursion and myocardial contractility differed significantly depending on the stimulation point. A moderate inverse correlation was found between ExcAvg, LVEF and QRS duration. There were a direct correlation of the SDI-16 and the QRS duration was shown, and an inverse correlation of SDI-16 with ExcAvg and LVEF. 2D longitudinal global strain was inversely correlated with the EF.

Conclusion. The technique is useful for regional LV myocardial contractility assessment and patient selection and comparison of alternative approaches to LV pacing to improve response to CRT.
Diagnostic imaging for DeBakey type III aortic dissection complicated by aneurysm rupture with the formation of an aortoesophageal fistula: a case report
Authors: Galyautdinova L. E. , Basek I. V. , Karpova D. V. , Chernyavskiy M. A. , Yegorova V. S. , Borshevetskaya A. A.
Published: April 2023

Aortic dissection is a type of acute aortic syndrome characterized by a high mortality rate in the first 48 hours. The problem of early diagnosis of acute aortic dissection is still relevant and due to a high risk of severe complications, as well as a non-specific clinical features. If left untreated, aortic dissection can be complicated by the formation of an aortic aneurysm and its rupture. Sometimes, the rupture of an aortic aneurysm is accompanied by the fistula formation. The article discusses the use of computed tomography (CT) scans for visualization of DeBakey type III aortic dissection complicated by aortic rupture and the formation of an aorto-esophageal fistula.

A 60 y.o. male diagnosed with aortic dissection was urgently transferred from the city hospital for surgical treatment. As part of the preoperative preparation, the patient underwent computed tomography angiography (CT angiography), that demonstrated not only an acute DeBakey type III dissection with a thoracic aortic aneurysm of the descending aorta, but also its complication in the form of aortic rupture with the formation of aorto-esophageal fistula.

The patient underwent a successful endovascular thoracic aortic stent grafting with unmarkable postoperative period. Follow-up CT angiography showed complete isolation of the false lumen and closure of the aorto-esophageal fistula. The patient showed clinical improvement and was discharged home on 14 day.
O możliwości etyki ewolucyjnej
Authors: Vollmer Gerhard
Published: April 2023

Eine "rein" philosophische - Ethik lässt zu viele Probleme ungelöst. Oie wenigen formalnen Bedingungen, die sich transzendentalphilosophisch, transzendéntalpragmatisch oder konstruktivistisch gewinnen lassen, reichen bei weitem nicht aus, um uns zu praktischen Handlungsanweisungen zu verhelfen. In die ser Situationistes wohl einen Versucht wert, sich auf die anthropologischen und damit letztlich biologischen Grundlagen der Ethik zu besinnen, lässtsich der "Evolutionären Erkenntnistheorie" eine "Evolutionäre Ethik” an die Seitestellen? Oder ist ein solches Unternehmen von vornherein zum Scheitern verurteilt? In diesem Beitrag werden Absichtund Besonderheit des evolutionären Ansatzes charakterisiert, wird der mögliche Beitrag der Soziöbiologie zur Ethik skizziert und werden die Einwände geprüft, die gegen eine solche Evolutionäre Ethik vorgerbracht werden (obwohl sie noch gar nicht existiert).
The results of surgery for giant aneurysms of the middle cerebral arteries: a retrospective study
Authors: Pilipenko Yuri V. , Eliava Shalva S. , Konovalov Anton N. , Grebenev Fyodor V. , Barchunov Boris V.
Published: April 2023

Background: Surgical treatment of middle cerebral artery (MCA) giant aneurysms is a challenging task. The information on its current principles is rather limited, with the publications based on isolated case reports and small series.
Aim: To identify the types of procedures and evaluate the results of surgery in patients with giant MCA aneurysms.
Materials and methods: We retrospectively analyzed the data on 55 patients who had undergone surgery for MCA giant aneurysms in the Burdenko Neurosurgery Center from 2010 to 2021. Thereafter 52 patients were followed up for 6 to 120 months (for 53.1 33.7 months on average).
Results: The giant MCA aneurysms were located at the M1 segment bifurcation in 33 (60%) patients, within the M1 segment, in 11 (20%), M2 in 7 (12.7%), and M3 and M4 in 4 (7.3%) patients. There were 32 (58.2%) saccular and 23 (41.8%) fusiform aneurysms. Surgical interventions for MCA giant aneurysms included their neck clipping (50.9%, n = 28), clipping with formation of the arterial lumen (3.6%, n = 2), bypass procedures (34.5%, n = 19), wrapping (3.6%, n = 2), and endovascular procedures (7.3%, n = 4). Perioperative worsening of the neurologic status (The Modified Rankin Scale, mRS) was observed in 50.9% (n = 28) of the patients, and the death rate was 1.8% (n = 1). The complete closure of giant aneurysms was achieved in 78.2% (n = 43) of the cases. The long-term outcome was favorable in 76.9% of the patients (40 from 52 available for the follow up).
Conclusion: Microsurgical clipping and bypass types of surgery were the most common surgical procedures for the treatment of MCA giant aneurysms. These procedures are technically complex and are associated with a relatively high number of complications. The main directions of future studies could be in the search for new and more precise diagnostic assessment of the collateral circulation in the cortical MCA branches, improvement of the algorithm for the bypass selection, as well as an investigation of the long-term results of endovascular and combined treatments. A thorough long-term postoperative patient follow-up and the possibility of high quality control angiography are of major importance.
Félix Denegrí Luna
Authors: Schwalb López Aldana Fernando
Published: April 2023

En este libro que tan acertadamente ha editado la Comisión de Homenaje a Félix Denegri Luna, deseo concretar mi participación, en pocas palabras, a la experiencia más reciente que tuve sobre el valioso aporte que hizo Félix a las tareas de la Comisión Consultiva de Relaciones Exteriores, cuya presidencia me ha tocado ejercer en los últimos años, particularmente en relación con el problema de la demarcación fronteriza con el Ecuador.
La biblioteca de las Tertulias
Authors: Tord Luis Enrique
Published: April 2023

La notable biblioteca de don Félix Denegri Luna no solo alcanzó el justo prestigio de ser el más selecto y numeroso repositorio contemporáneo de libros y revistas, a más de periódicos del siglo XIX del Perú, sino que se constituyó también en lugar obligado donde recalaban historiadores de diversas generaciones tanto del país como del extranjero.
Discurso en la ceremonia de entrega de la condecoración post-mortem de la Orden Nacional "Al Merito" al doctor Félix Denegri Luna
Authors: Sevilla Borja Horacio
Published: April 2023

Discurso dado por el embajador del Ecuador Horacio Sevilla Borja
The effectiveness of asynchronous online role-play on ESL learners’ willingness to communicate
Authors: Madzlan Noor Alhusna , Zulkepli Noraini , Shukor Siti Shuhaida , Bahari Aireen Aina
Published: April 2023

This paper investigates the use of asynchronous online role-play as a learning technique to improve ESL learners’ willingness to communicate. This study proposes two research objectives; to investigate the significant difference in ESL learners’ willingness to communicate before and after performing asynchronous role-play and to identify factors that impact the ESL learners’ willingness to communicate. A mixed-methods approach is used to understand the impact of the intervention. A set of questionnaires, reflective journal entries and a semi-structured interview were administered to tertiary level ESL students. Results from this study revealed that willingness to communicate among the participants in the treatment group significantly increased with the aid of asynchronous online role-play. Other findings identified factors such as self-confidence, teamwork, linguistic and non-linguistic factors as well as technical skills that show the feasibility of the asynchronous online role-play. The practical implications of this study would allow further exploration of learning techniques in the post-pandemic phenomenon of English language teaching and learning.
The Online Gaming Behaviour of University Students Undergoing Self-Quarantine
Authors: Fahrizal Yanuar , Wati Anisa Risma , Sutarjo Puji , Martin Neil M
Published: April 2023

Self-quarantining is one of the coping mechanisms used during the pandemic. However, it can negatively affect the sufferer. Self-quarantine causes many students to play online games excessively. Understanding students' online game behavior during self-quarantine can help to prevent online game addiction and encourage positive self-quarantine activities. This study aims to investigate the online gaming experience during self-quarantine for university students who tested positive for COVID-19 during the pandemic. Phenomenological qualitative research was used. The study’s sample consists of ten university students from Yogyakarta who tested positive for COVID-19 and played online games during self-quarantine. Purposeful sampling was utilized, and data were collected through semi-structured in-depth interviews. The Colaizi method was then used to analyze the data. The results indicated four themes: (1) the changes in online gaming behaviors before and after being tested positive for COVID-19; (2) the influencing factors on online gaming behavior before and during self-quarantine, (3) the impacts of parenting styles on online gaming behaviors, and (4) the impacts/consequences of online gaming behaviors. Overall, during self-quarantine, the students changed their behavior during online gaming, which was influenced by internal and external factors. They also became aware of the consequences of excessive online gaming
Emotional At Work: Stress-Strain-Outcome Model Perspective
Authors: Suroso Agus , Gal Timea , Anggraeni Ade Irma
Published: April 2023

Contemporary studies regarding emotional dissonance in the workplace emphasize the need for organizational attention focusing on employees' emotional dissonance. Job demands require employees to display emotions that are different from the natural feelings of employees. Specifically, employees who work in hospitality-based companies understand the importance of positive expression as a component of professionalism in delivering services. However, this condition will have an impact on employee behavior such as the intention to leave the organization. Employees choose to stay in the organization if they are satisfied with their work. Organizational support becomes important for employee satisfaction. This study examined the effect of emotional dissonance and organizational support on intention to leave the organization, mediated by job satisfaction. Respondents in this study were employees who worked in hotels in two countries including Indonesia and Hungary. The results of this study contribute to explaining the stress-strain-outcome (SSO) model, especially the influence of emotions on employee behavior in the workplace
Prurarilingualism and International Corporation for Enhancing the Image of Private School in Banyumas Region
Authors: Asiati Tri , Herliana Monika , Utami Riski
Published: April 2023

School is a special social space in preparing the futur generation, which not only forms cognitive, psycho-motor, and affective aspects, but also a forum for socio-cultural development. As a social instrument, the diversity of situations contributes to theirs images which is clearly reflected in the generally image of schools in Indonesia, and particularity in Banyumas region, including the demarcation of public and private schools. This dichotomy directly implies a different quality for the image of private schools which are often considered a marginal areas, even though both public and private schools have their own uniqueness in preparing their students. Recently, there has been a strategy through prurarilingual teaching programs to deal with the phenomenon of globalization. In reality, the implementation of this strategy is still far from perfect in preparing young Indonesians who are dynamic academically and professionally. This is because the prurarilingualism aspects have not been integrated that support the language competence of the learners. As a result, prurarilingual teaching as a strategy for enhancing the image of a private school serves only as a slogan, and not as a milestone. Therefore, through the application of a prurarilingualism program that focuses on developing: (1) paralinguistic behavior: (i) body language, (ii) using anomatope, and using (iii) prosody, and (2) paratextual behavior: (i) illustration and ( ii) typography, is expected to be able to improve the image of private schools that make multilingual programs as an imaging strategy which is also supported by international corporation networks
Implementation of Lean Manufacturing with Waste Assessment Model (WAM) Approach in A Small Muffler Industry in Purbalingga
Authors: Inderawibowo Zalfa A , Asyari Hasyim , Sibarani Ayu Anggraeni
Published: April 2023

Small to medium-sized industry (SMEs) is one of the sectors that supports the Indonesian economy, for example in Purbalingga Regency there is MMS K477INE. MMS K477INE is an SME that produces various types of muffler or muffler of a motorbike and it has entered the global market, one of them is a 2 stroke muffler type RX King Telo Kobra. In the muffler production process, it must be done better to fulfill customer demand and satisfaction. However, from the implementation of activities on the production floor, there are several problems so it cannot be denied that the SME there is a waste. Therefore, in this case, it is necessary to apply a lean manufacturing approach to solve the problem using the Waste Assessment Model (WAM). WAM consists of Seven Waste Relationship, Waste Relationship Matrix, and Waste Assessment Questionnaires, which data collection is done through filling out questionnaires and direct observation. The WAM approach is used to find the problem of waste and is supported by the root causes of waste by using Root Cause Analysis. The next stage is to create a recommendation improvement, based on the problems that occur in the highest value waste is motion waste with a value of 26.7%, defect with a value of 18.5%, and transportation with a value of 14%. So that the recommendation improvement that has been created can reduce the value of waste
Prevalence and diversity of ciprofloxacin-resistant Klebsiella pneumoniae clinical isolates
Authors: Sulistiyawati Indah , Wahyono D J , Siswandari W
Published: April 2023

The persistence and proliferation of multidrug-resistant microorganisms have the potential to occur in health centers and patient care units. WHO reports that cases of Klebsiella pneumoniae infection treated with ciprofloxacin in 34 countries have resistance from 4.1% to 79.4%. This study aimed to analyze the prevalence and diversity of ciprofloxacin-resistant K. pneumoniae from patients at Margono Soekardjo Hospital, Purwokerto. This study used a purposive sampling technique from blood, sputum, urine, pus, feces, and pleural fluid. The research process includes isolates characterization and identification, ciprofloxacin resistance testing, and its prevalence. This study recorded 99 cases of K. pneumoniae infection, and 48.5% of isolates were resistant to ciprofloxacin from August-September 2022. Biochemical and morphological tests showed a characteristic diversity of isolated K. pneumoniae against K. pneumoniae subspecies pneumoniae. The prevalence of ciprofloxacin-resistant K. pneumoniae was from blood (7.1%), sputum (59.6%), pus (23.2%), urine (6.1%), feces (3.03%), and pleural fluid (1.01%).
Economic Recovery after the Covid 19 Pandemic of Utilization of Village-Owned Enterprises in Indonesia
Authors: Laksana RIO Dhani , Adi Pramono Hari , Suwandari Lusi
Published: April 2023

The results of this study concluded that: 1) Village income during the COVID-19 pandemic decreased due to limited community activities outside the home and reduced public spending. The decline in income from large events such as weddings and celebrations caused the rent for tents and other Bumdes income to decline. 2) The village party is now using a marketing strategy where activities outside the home such as the opening of the market and the community can return to their activities outside the home on the condition that they comply with the protocols set by the government such as keeping a distance and wearing masks. 3) The results of declining income during the covid pandemic Village-Owned Enterprises affect the level of community welfare with the income they get. 4) BUMDes besides being able to improve public services and optimize village assets, also play a role in supporting, facilitating, and coordinating the productive economic efforts of rural communities. BUMDes can be the parent of ecotourism activities or village ecotourism. BUMDes plays an important role in providing convenience services in saving and borrowing small-scale business capital for productive businesses of rural communities in collaboration with external parties (both banks and private companies).
Motivating Factors Analysis for Halal Certification on the Catering and Restaurant Services in Banyumas Regency
Authors: Putri Astrid Lastani Sukmana , Hidayat Hety Handayani , Siswantoro Siswantoro , Wijayanti Nur
Published: April 2023

Halal certification guarantees that a product is halal for consumption or use, especially for Muslim consumers. However, the number of halal-certified restaurants and catering services in Banyumas Regency, with its predominantly Muslim population, is still minimal. Therefore, this study analyzes the motivational factors for Halal certification in the hospitality industry. The method used is a multiple linear analysis with 9 motivational factors obtained from an in-depth literature study. The regression model formed has an R square value of 48.1%, meaning that 48.1% of the nine factors studied can explain the existing motivation. From the t-test, it is known that 7 factors significantly affect the motivation of restaurant and catering business owners in halal certification, namely customer awareness, religion, the role of halal certificates, increased turnover, halal producer awareness, globalization, and the environment. Based on these results, it is hoped that it can be used by related parties to increase motivation so that there is an acceleration of halal certification to support the food and beverage obligation program in Indonesia in 2024.
Improvement the practices of complementary feeding through local wisdom-based complementary feeding education videos
Authors: Purnamasari Meivita Dewi , Setiyowati Erni , Wahyurin Izka Sofiyya
Published: April 2023

The incidence of stunting is a major nutritional problem faced by Indonesia. The most decisive intervention to reduce the prevalence of stunting includes the provision of complementary foods to infants. Empowerment of mothers during the complementary feeding period can give positive results on the nutritional status of children. The purpose of the study was to identify the effect of MPASI education videos based on local wisdom on maternal practices and nutritional status of infants 6-24 months. The research design was a quasi-experimental with a two group pre-post test design, sample of 40 mothers of infants 6-24 months which taken by consecutive sampling. The results showed that there were differences in mother's practice before and after the complementary feeding education video (p value < 0.001; = 0.05), while there was no difference in nutritional status before and after the video was given. This study recommends providing MPASI educational media for mothers during the exclusive breastfeeding period as a preventive measure for early complementary feeding and increasing maternal readiness before the complementary feeding period.
Data-Based Policy as a solution to overcome illegal mining of Mount Botak, Buru Regency, Mollucas Province for sustainable development
Authors: Martanto Dwiana , Nasihuddin Abdul Aziz
Published: April 2023

Gold mining in Mount Botak, Buru Regency, Mollucas Province is processed traditionally so that it produces waste containing heavy metals that are harmful to human health and cause environmental damage. Although the government has taken various control measures in the form of judicial operations, they have not been effective in stopping illegal mining activities, even indigenous peoples in the name of customary rights have urged the government to manage them professionally for economic reasons. The Buru Regent is challenged to make legal policies that respond to the demands of the community while at the same time paying attention to environmental sustainability. This study aims to find the ideal policy concept for overcoming illegal mining that supports environmental sustainability. To achieve this goal, doctrinal legal research is used based on a conceptual approach, with a positivist paradigm, and relies on normative juridical research, and deductive analysis. The results of the study show that a data-based policy model that is supported by science becomes a reliable policy and supports sustainable environmental development
Ganoderma lucidum as Anti-Inflammatory Agent on The Level of Albumin and Globulin in Rat (Rattus Norvegicus) Rheumatoid Arthritis (RA) Model
Authors: Tiyah Sesti Wan , Ratnaningtyas N I , Wibowo E S , Mumpuni A , Ekowati N
Published: April 2023

Abstrak: Inflammation is one of the immune system's responses to infection, irritation, also cell damage. Inflammation stimulates pro-inflammatory biomarkers. Albumin and globulin are included as inflammatory biomarkers, albumin is a negative acute phase protein (-APP), which will decrease, and globulin is a positive acute phase protein (+APP), which will increase due to inflammation. Ganoderma lucidum is a medicinal mushroom with anti-inflammatory potential that could increase the albumin level in blood due to inflammation. This research aimed to examine the effect of G. lucidum extract on the albumin and globulin level of inflamed white rats anddetermine the most effective dose of extract to be an anti-inflammatory agent. The study was conducted with a completely randomized design (CRD) consisting of 6 treatments of healthy control (HC), inflamed rats as negative control (C-), inflamed rats with Na-diclofenac administration (C+), and inflamed rats with G. lucidum extract administration with a dose of 250, 500, 750 mg/kg BW (T1, T2, and T3) with four replications each. The independent variable is the dose variant of   G. lucidum (250, 500, 750 mg/kg BW), with the dependent variable being the changesin albumin and globulin levels. The main parameters are albumin and globulin levels, and the support parameter is the GC-MS test. The data were processed using Analysis of Variance (ANOVA) at an error rate of 5%, followed by Duncan's analysis at 95% confidence level. The results show that mushroom G. lucidum extract administration with a dose of 250 mg/kg BW is the most effective dose to be ana dose of 250 mg/kg BW, which is the most effective anti-inflammatory agent.
THE EXISTENCE OF CUSTOMARY LAW AS THE LOCAL WISDOM OF THE KUTA VILLAGE CUSTOMARY LAW COMMUNITY IN PROTECTING AND MANAGING THE ENVIRONMENT
Authors: Inayah Wafa Nihayati
Published: April 2023

We can understand the local wisdom that exists in a community as noble cultural values that usance to regulate the order of people's lives wisely. This wisdom is not only in the form of cultural norms and worth, but also all elements of life in it since becoming representations of the way of life. Likewise, the unique cultural life of the indigenous law community of Kuta village is a community that still firmly holds and carries out traditions with the supervision of Duncan and its traditional leaders. This study aims to look into the values of local wisdom of the indigenous people of Kuta village that have been institutionalized until now, especially traits in protecting and managing the environment. The approach method in this research is empirical juridical or legal research and can also be called field research. This research seeks to identify the laws that exist in society. The concept of legal pluralism no longer develops in the realm of the dichotomy between state legal systems. At this stage of development, legal pluralism emphasizes the interaction and co-existence of various legal systems that affect the work of norms and legal processes in society. In the customary law community of Kuta Village in Karangpaningal Village, Tambaksari District, Ciamis Regency, which is represented in the tradition of building residential houses, enforcing prohibition forests, respect for sacred places, and trust in their ancestors.
The Role of ASEAN through ASEAN Integrated Food Security Framework (AIFS) in Achieving Indonesia’s Food Security
Authors: Miryanti Renny , Wijayanti Sri , Saadah Kholifatus , Agustiningsih Ayu
Published: April 2023

The report of 2021 hunger map of the World Food Program of the United Nations (WFP) shows that even though Southeast Asia has fertile land and is surrounded by maritime wealth, however many ASEAN (Association of Southeast Asian Nations) countries still has a number of poverty and inability to access food and nutrition. ASEAN through the AIFS (ASEAN Integrated Food Security) Framework encourages ASEAN countries try to achieve ASEAN regional food security. This study will examine the role of ASEAN through AIFS (ASEAN Integrated Food Security) in achieving Indonesia’s food security. This research used qualitative method, and the collecting data used primary data collection conducted through interviews with related parties, and secondary data through literatures review related to the role of ASEAN through ASEAN Integrated Food Security Framework or other food security policies. The theory of international organization role is used to answer the research question. This research found that ASEAN through AIFS framework plays role as an arena rather than instrument and independent actor in achieving food security in Indonesia.
Long Covid, POTS, and ME/CFS: Lifting the Fog
Authors: Chambers Patrick
Published: April 2023

These three syndromes - long covid (LC), postural orthostatic tachycardia syndrome (POTS), and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) - have many symptoms in common. The common denominator remains elusive. The blood brain barrier (BBB) has been a barrier not only to microbes and toxins but also to understanding pathogenetic links. There are several areas within the brain that have no BBB. These are known as circumventricular organs (CVOs) and their location relative to CNS nuclei that direct autonomic and neuroendocrine functions is provocative in the quest for pathogenesis. In addition the majority afflicted with LC and ME/CFS appear to be those with two MTHFR polymorphisms, present in over 50% of Americans. These polymorphisms elevate homocysteine. When homocysteine is combined with CVOs, the fog of POTS and its paradox are lifted. POTS may represent the intersection of LC and ME/CFS in those with the MTHFR gene (hypermethylation or 677TT). The gut microbiomes of LC and ME/CFS, deficient in butyrates, GABA, and diversity, are then linked with MTHFR genotype 677TT. Reactivation of neurotropic EBV and VZV, due to loss of surveillance by CD4+/CD8+ T cells, is seen as secondary. The oxidative stress generated by homocysteine, loss of glutathione, low fiber diet, and persistent chronic inflammation exhaust available mitochondria and, assisted by BKN and estrogen, exacerbate all the elements of these post viral fatigue syndromes.
A Common Approach to Three Open Problems in Number Theory
Authors: Tyszka Apoloniusz
Published: April 2023

The following system of equations {x_1 \cdot x_1=x_2, x_2 \cdot x_2=x_3, 2^{2^{x_1}}=x_3, x_4 \cdot x_5=x_2, x_6 \cdot x_7=x_2} has exactly one solution in ({\mathbb N}\{0,1})^7, namely (2,4,16,2,2,2,2). Hypothesis 1 states that if a system of equations S \subseteq {x_i \cdot x_j=x_k: i,j,k \in {1,...,7}} \cup {2^{2^{x_j}}=x_k: j,k \in {1,...,7}} has at most five equations and at most finitely many solutions in ({\mathbb N}\{0,1})^7, then each such solution (x_1,...,x_7) satisfies x_1,...,x_7 \leq 16. Hypothesis 1 implies that there are infinitely many composite numbers of the form 2^{2^{n}}+1. Hypotheses 2 and 3 are of similar kind. Hypothesis 2 implies that if the equation x!+1=y^2 has at most finitely many solutions in positive integers x and y, then each such solution (x,y) belongs to the set {(4,5),(5,11),(7,71)}. Hypothesis 3 implies that if the equation x(x+1)=y! has at most finitely many solutions in positive integers x and y, then each such solution (x,y) belongs to the set {(1,2),(2,3)}.
Challenges and Solutions for Autonomous Ground Robot Scene Understanding and Navigation in Unstructured Outdoor Environments: A Review
Authors: Wijayathunga Liyana , Rassau Alexander , Chai Douglas
Published: April 2023

The capabilities of autonomous mobile robotic systems have been steadily improving due to recent advancements in computer science, engineering, and related disciplines such as cognitive science. In controlled environments, autonomous robots have been able to achieve relatively high levels of autonomy. In more unstructured environments, however, the realisation of autonomous mobile robots remains challenging due to limitations in the robots’ external environment understanding. Many autonomous mobile robots use classical, learning-based or hybrid approaches for navigation. The classical navigation approach typically includes robot perception, localisation, environmental mapping, path planning and motion control stages. More recent learning-based methods may replace the complete navigation pipeline or selected stages of the classical approach. For effective deployment, autonomous robots need to be able to understand their external environments at a sophisticated level according to their intended applications. Therefore, in addition to robot perception, scene analysis and higher-level scene understanding (e.g., traversable/non-traversable, and rough or smooth terrain) are required for autonomous robot navigation in unstructured outdoor environments. A wide number of alternative approaches have been proposed in recent years to attempt to address these scene understanding requirements. This paper provides a comprehensive review and critical analysis of these methods in the context of their applications to the problems of robot perception and scene understanding in unstructured environments, and the related problems of localisation, environment mapping and path planning. State-of-the-art sensor fusion methods and multimodal scene understanding approaches are also discussed and evaluated within this context. The paper concludes with an in-depth discussion regarding the current state of the autonomous ground robot navigation challenge in unstructured outdoor environments and the most promising future research directions to overcome these challenges.
Metallacarborane Synthons for Molecular Construction - Func-tionalization of Cobalt bis(1,2-dicarbollide) with Extendable Ligands
Authors: Śmiałkowski Krzysztof , Sardo Carla , Leśnikowski Zbigniew
Published: April 2023

The exploitation of the metallacarboranes’ potential in various fields of research and practical ap-plications requires the availability of convenient and versatile methods for their functionalization with various functional moieties and/or linkers of different types and lengths. Herein we report a study on cobalt bis(1,2-dicarbollide) functionalization at 8,8’-boron atoms with different het-ero-bifunctional moieties containing protected hydroxyl function allowing further modification after deprotection. Moreover, an approach to the synthesis of three and four functionalized metallacarboranes, at boron and carbon atoms simultaneously, via additional functionalization at carbon to obtain derivatives carrying three or four rationally oriented and distinct reactive surfaces, is described
Four Weeks of Incline Water Treadmill Exercise Increases Epaxial Muscle Profile in Horses
Authors: Fair Natalie , Blake Scott , Ferro de Godoy Roberta
Published: April 2023

Background: Water treadmill (WT) exercise is a popular modality for the training and rehabilitation of horses. However, evidence-based literature regarding the use of WT exercise, particularly using inclines, is lacking.Objectives: The aim of this study was to assess the effect of recurring inclined WT sessions on equine epaxial muscles development.Methods: Six horses completed 24 sessions of 15 minutes of WT activity over four weeks. Horses walked with water at mid-cannon level at a treadmill incline of 4%. Back traces were measured at three and seven centimetres ventral to the dorsal midline at T5, T9, T14 and T18, prior to the first session (W0) and weekly for 4 weeks (W1-4). Results: Overall the back traces demonstrated progressive increases in muscle development (p<0.05), starting at W2 up to W4. At three centimetres ventral to the dorsal midline the most to least significant increases in gross muscle development were at T18, T5, T9 and T14, respectively and when measured at seven centimetres ventrally, the most to least significant increases were demonstrated at T5, T18 and T14 . It was noted that increases in thoracic back profile musculature were mainly observed within two to four weeks of the WT intervention.Conclusions: It has been concluded that repeated WT exercise on an incline setting has a significant effect on the rate and size of growth of equine thoracic back profile musculature. Muscle hypertrophy due to resistance training in the WT starts at 2 weeks within the programme, and it progresses as exercise continues to be performed.