bluuebunny/crossref_metadata_2025 huggingface dataset:
Recent efficacy and safety analysis of neoadjuvant therapy with Tislelizumab combined with Apatinib and chemotherapy in Borrmann type IV, large Borrmann type III, and Bulky N locally advanced gastric cancer(3-B).
Authors: Wei Shenghong , Ye Zaisheng , Wei Cheng , Wang Yi , Zeng Yi , Chen Jinhu , Liu Guoquan , Chi Yuanlong , Lin Qisheng , Wang Jingwei , Liu Sheng , Chen Shu , Jiang Jianping , Wang Xiaopeng , Chen Xiaoling , Chen Xiaoqi , Chen Luchuan
Published: July 2024

Background
To explore the efficacy and safety of immune checkpoint inhibitor Tislelizumab combined with Apatinib and chemotherapy in the neoadjuvant therapy of Borrmann IV, large Borrmann III and Bulky N locally advanced gastric cancer.
Methods
Patients with untreated, Her-2-negative, resectable locally advanced gastric adenocarcinoma (Borrmann IV, large Borrmann III, and Bulky N) were enrolled. Preoperative neoadjuvant therapy with tirelizumab combined with apatinib and SOX regimen was performed for 3 to 6 cycles. 3 cycles of evaluation, if PR, surgery; if SD, continue neoadjuvant therapy, after 6 cycles of re-evaluation of surgery.
Results
Forty patients were recruited, large Borrmann III in 26 cases, Borrmann IV in 6 cases, and Bulky N in 8 cases. The results of the radiographic evaluation were as follows: PR in 36 cases (90%), SD in 3 cases, PD in 1 case, and ORR rate was 90%. All patients underwent D2 or D2 + surgery, including R0 resection in 37 cases and R2 resection in 2 cases. Pathological effects: ypCR (TRG0) in 7 cases (17.9%), TRG1 in 9 cases, TRG2 in 18 cases, TRG3 in 5 cases. The MPR rate was 40.0%. Grade 3 to 4 adverse reactions occurred in 19 patients (47.5%) during neoadjuvant therapy. The incidence of postoperative complications was 33.3%, and grade IIIA or above was 7.7%, no perioperative death occurred.
Conclusion
For Borrmann IV, large Borrmann III, and Bulky N-positive, locally advanced gastric cancer, the triple regimen of Tislelizumab combined with Apatinib and chemotherapy can achieve clinical benefit with acceptable safety.
Clinical Trial Registration:
Registered with ClinicalTrials.gov, registration number NCT05223088.
Harnessing the Collective Potential of Lanthanide Single-Atom Catalysts for Efficient CO2-to-CO Electroreduction
Authors: Liu Min , Wang qiyou , Luo Tao , Cao Xueying , Gong Yujie , Liu Yuxiang , Li Hongmei , Lu Ying Rui , Chan Ting-Shan , Ma Chao , Liu Kang , Fu Junwei , Zhang Shiguo , Liu Changxu , Zhang Lin , Liyuan Chai
Published: July 2024

Single-atom catalysts (SACs) have received increasing attention due to their 100% atomic utilization efficiency. The electrochemical CO2 reduction reaction (CO2RR) to CO using SAC offers a promising approach for CO2 utilization, but achieving facile CO2 adsorption and CO desorption remains challenging for traditional SACs. Instead of singling out specific atoms, we propose a novel strategy utilizing atoms from the entire lanthanide (Ln) group to facilitate the CO2RR. Density functional theory calculations, operando spectroscopy, and X-ray absorption spectroscopy elucidate the bridging adsorption mechanism for a representative erbium (Er) single-atom catalyst. Remarkably, we realize a series of Ln SACs spanning 14 elements that exhibit CO Faradaic efficiencies exceeding 90%. The Er catalyst achieves an ultrahigh turnover frequency of ~ 130,000 h‒1, accompanying with a remarkable 42.6% full-cell energy efficiency and record-high 94% single-pass CO2 conversion efficiency. This unparalleled catalytic platform leverages the collective potential of the lanthanide group, introducing new possibilities for efficient CO2-to-CO conversion and beyond through the exploration of unique bonding motifs in single-atom catalysts.
Environmental factors in the development of Coronary Artery Atherosclerosis
Authors: Siddiqui Ifrah , Ahmad Fatima , Khan Nabeel Ahmad , Naeem Almas , Kumar Mahesh , Khalid Muhammad Usaid
Published: July 2024

Objective:
This study aims to comprehensively investigate the role of environmental factors—diet, physical activity, tobacco smoke, air pollution, psychosocial factors, occupational exposures, noise pollution, climate factors, urbanization, and socioeconomic status—in the pathogenesis of coronary artery disease (CAD).
Background:
Coronary artery disease (CAD) poses a significant global health challenge influenced by a complex interplay of environmental, behavioral, and socioeconomic factors. These factors contribute to inflammation, endothelial dysfunction, atherosclerosis, plaque rupture, and thrombosis, underscoring the need for a holistic understanding to inform effective preventive and therapeutic strategies.
Methods:
A systematic review was conducted across PubMed, MEDLINE, Google Scholar, and various journals to identify relevant studies on environmental factors and CAD. The search encompassed articles without date restrictions, adhering to PRISMA guidelines. Studies exploring causal links between environmental factors and CAD pathophysiology were included, with data synthesized to elucidate key mechanisms and relationships.
Results:
The investigation highlights complex connections between environmental factors and CAD pathophysiology. Diets high in saturated fats and sugars exacerbate inflammation and endothelial dysfunction, while diets rich in antioxidants and omega-3 fatty acids mitigate these effects. Physical activity enhances endothelial function and reduces inflammation markers, promoting plaque stability. Tobacco smoke and air pollution are linked to increased inflammation, endothelial dysfunction, and plaque instability. Psychosocial stressors, occupational exposures, noise pollution, climate variations, urbanization, and lower socioeconomic status similarly contribute to CAD progression through diverse mechanisms.
Conclusion:
This study underscores the multifaceted impact of diet, physical activity, tobacco smoke, air pollution, psychosocial factors, occupational exposures, noise pollution, climate factors, urbanization, and socioeconomic status on CAD pathogenesis. Understanding these causal links is critical for developing comprehensive strategies to mitigate CAD risk and improve cardiovascular outcomes globally. Integrated public health initiatives and targeted policy interventions addressing these factors are essential for effective CAD prevention and management.
THE HUMAN VARIABLES WITHIN BUDGETARY CONTROL AND THEIR IMPLICATIONS ON FINANCIAL PERFORMANCE AT HEIS
Authors: Tsyhaniuk Dmytro , Akenten Wiafe
Published: July 2024

Budgets and budgetary controls are important components of management control intended to encourage resource utilization efficiency in support of the achievement of company strategic goals. Budget control aims to observe transparency and legality at all stages of the budget process to ensure responsible and effective performance by the state of its functions and tasks regarding the formation and spending of budget funds. This study evaluates how employee budget involvement and performance relate in a Ghanaian public university, specifically the University of Education. The University of Education was chosen as the study location to determine the relationship between budget participation and employee performance in Ghana's public universities. Because the government owns 100% of Ghana's public universities and because these institutions are subject to government oversight, the researchers believe that using a single case study is suitable. Throughout the investigation, a multi-analysis and participative strategy was used. Employee performance is evaluated for the research based on how well they contribute to the organization's achievement of the budget objective. The study's particular focus is on the behavioral aspects of budgeting procedures and the effect of budget participation on employees' effectiveness in meeting defined budgetary objectives. The researcher chose 110 respondents who are University of Education staff members using basic random sample and convenience sampling procedures. It is clear from our study that employee participation in the budgeting process is the cornerstone of achieving budget goals because it will enable employees to have a clear understanding of what the budget is meant for, have a voice by ensuring that resources are distributed fairly among departments and faculties of the university. From this, it is obvious that we accept our null hypothesis, according to which budget participation increases employees' performance and their view of the fairness of resource distribution and budget goal clarity. Future studies might also encompass the perspectives of key management figures such as Registrars, Directors of Finance, Vice Chancellors, and other essential officers who play significant roles in the budgeting process of these public universities.
Расчет и коррекция дозы цитостатических препаратов в режимах кондиционирования перед аллоТГСК у пациентов с избытком массы тела или ее дефицитом
Authors: Карпенко Елена Юрьевна , Дроков М. Ю.
Published: July 2024

In Russia, like in the rest of the world, the number of overweight people has been growing for the last 20 years. According to different studies, obesity and overweight incidence among adults is 20.5–54.0 %. Obesity incidence increased from 10.8 % in 1993 to 27.9 % in 2017 in men and from 26.4 to 31,8 % in women, respectively. Pharmacokinetics of drugs including cytostatic agents, differs in obese vs. normal-weight patients. This is accounted for by renal/hepatic clearance changes as well as by increased distribution of lipophilic drugs with their enhanced protein-binding ability. All these factors create a challenge for a correct calculation of drug doses for obese patients. This issue becomes particularly acute when such patients undergo allogeneic hematopoietic stem cell transplantation with preconditioning regimens using sublethal drug doses. This paper attempts to review current approaches to drug dose calculation to be used in preconditioning regimens for over- and underweight patients.
Competence-based ranking in training of specialists in the field of strategic communications, advertising and public relations
Authors: Baturina V. Y. , Golubeva V. I. , Malygina A. M.
Published: July 2024

The article represents the authors’ methodology in assessing the level of professional training of specialists in the field of advertising and public relations within the framework of competence-based approach to education. The authors consider it insufficient to rank the students based on purely academic performance and suggest changing the existing criteria to assess the level of acquired skills and competences required in the future profession. To increase the learning motivation, it is suggested to use the creative potential of future public relations specialists. The authors’ approach involves the introduction of gamification elements, including scenes and vocabulary known to students from computer games. Special attention is paid to transparent and visual organisation of ranking tables. Such ranking has been tested at MGIMO – University for a number of years and has shown an increase in motivation and, as consequence, learning outcomes. This methodology may be used to improve the efficiency of the educational process in advertising, strategic communications, public relations, branding, and similar disciplines in humanities and social studies where competences are an integral part of professional training.
Model of electoral behavior of russian citizens in the conditions of digitalization of the electoral process
Authors: Kiryushin I. A.
Published: July 2024

The introduction of information and communication technologies (hereinafter referred to as ICT) occurs not only in sectors of the country’s national economy, but is widely used in the electoral process. Moscow has accumulated some experience in introducing and effectively using ICT during the preparation and conduct of election campaigns. In the fall of 2023 shortly before the election of the Mayor of Moscow, the author conducted a survey of residents of the capital city. The organizers of the survey of the citizens were tasked with collecting, summarizing and analyzing the opinions of the Moscow electorate on the issue of introducing digital technologies in elections. The article provides specific results of a survey of Muscovites, their attitude towards the use of electronic technologies in the elections. The author argues about the advisability of increasing the legitimacy of elected authorities by increasing the voter turnout indicator. Specific examples demonstrate that the introduction of digitalization into the electoral process ultimately helps to increase the legitimacy of elected parties, public associations and their candidates. Analyzing the results of the elections to federal, regional and local executive and legislative bodies in recent years (2021–2024), as well as the results of the above-mentioned survey of Moscow residents, the author proposes an option for constructing a causality model using an external factor such as digitalization, which has a significant influence on the electoral process.
Analysis of employment factors for university graduates in Kazakhstan
Authors: Sekerbayeva Aigerim , Tamenova Saltanat , Tarman Bulent , Razakova Dina , Satpayeva Zaira
Published: July 2024

Having a university degree provides only a slight advantage over those without higher education, making other factors crucial in determining a graduate’s employment prospects. This study aims to analyze the factors that affect the employment of university graduates and define opportunities for public administration and university management in Kazakhstan. A logistic regression model based on primary data was used to examine the impact of the availability of practical experience and jobs in their specialty, social connections, technology development, and entrepreneurship on the likelihood of employment. The survey was conducted in 2022 and involved 300 graduates of the 2020–2021 academic year from all regions of Kazakhstan. Findings show that personal connections (F3) and technology and entrepreneurship (F4) positively impact graduates’ job prospects. However, lack of experience (F1) and the limited number of job offers (F2) reduce employment likelihood. If a graduate responds with 3 points for F1, 7 for F2, 7 for F3, and 1 for F4, they are less likely to secure a job in their specialty within a year of graduation. The main practical value of this study is that university career centers can use this model to predict the likelihood of graduates being employed. Providing a sophisticated online platform and different analytics-driven career services, open access to administrative data on the labor market, and new programs for students’ job experience and entrepreneurship will prepare university graduates for a dynamic labor market and reduce the mismatch between education and employment needs.
HABER DEĞERLERİNE YÖNELİK BİR İÇERİK ANALİZİ: WHATSAPP GAZETECİLİĞİ VE DNA WHATSUP HABER ÖRNEĞİ
Authors: Kurt Yılmaz Gözde
Published: July 2024

Çalışmada, DNA WhatsUp Haber’in 1 Temmuz 2023-21 Temmuz 2023 tarihleri arasında WhatsApp’ta paylaştığı 491 haberde ön plana çıkan haber değerleri, duygu tonu ve duygu türünün içerik analizi yönteminden yararlanılarak incelenmesi amaçlanmaktadır. Araştırmada duygu tonu sınıflandırmasında haberlerin pozitif, negatif ve nötr duygu çağrışımları, duygu türü sınıflandırmasında ise endişe, ilgi duyma, korku, memnuniyet, merak, öfke ve şaşkınlık gibi öne çıkan duygular tanımlanmıştır. Araştırma sonucunda elde edilen bulgulara göre, haberlerde en yüksek oranda siyasetin konu edildiği, en fazla güncellik, önemlilik, ilgi düzeyi ve ilginçlik şeklindeki haber değerlerinin ön planda olduğu, baskın duygu tonunun nötr (% 70,5) ve negatif (% 27,3) olduğu, pozitif tonlu haberlerin ise % 2,2 düzeyinde kaldığı ortaya koyulmuştur. Haber içeriklerinde belirlenen en baskın üç duygu türü ise endişe / kaygı, şaşkınlık ve öfke / kızgınlıktır. Haberlerde emoji kullanımının ise haberin duygu tonu ve duygu türünü belirlemede önemli bir faktör olduğu ve haberin öznel bir değerlendirme ile sunulmasına yol açtığı değerlendirilmektedir. .
Development of an Ethnoscience-Based Integrated Science Module with RIAS Learning Model to Improve Students' Critical Thinking Ability
Authors: Fadilah Arum Maharsi , Muhlisin Ahmad , Ismawati Riva
Published: July 2024

The ability to think critically is an important competency that students must have in the 21st century, especially in the implementation of Curriculum Merdeka. However, in practice, there is a lot of learning process without training to improve critical thinking skills. So a solution is needed, namely the development of teaching materials such as modules that can overcome this problem. This research uses the Hannafin Peck model development research form. The product is an integrated science module based on ethnoscience aspects at the Nglipoh Magelang pottery industry. This module is also integrated with the RIAS learning model which also facilitates students' critical thinking skills. The validity test obtained results of 3.32 from media experts and 3.66 from material experts so it is declared very valid. The effectiveness test with an N-Gain obtained a result of 0.74, so it can be concluded to be very effective. The practicality of the module was also analyzed based on a questionnaire with a result of 83.18% so it can be concluded that this module is very practical to use. The conclusion of this research is that the module is suitable for implementation to improve students' critical thinking skills.
Development Magnetic Science Park Props Based On Science Literacy To Improve Understanding Concept Of Magnetic Force In Grade IV Elementary School
Authors: Sianturi Magdalena Ernesta
Published: July 2024

Teaching aids are tools that help teachers convey abstract material to be more concrete in classroom learning. The props in the development research aim to form science literacy skills to make it easier for grade IV elementary school students to understand the concept of magnetic force. This research is based on the level of understanding of students' concepts related to magnetic force which is still low, due to the lack of variation in the use of media/tools in science learning in the classroom and the lack of student learning motivation. This research is a development research (DD) with the ADDIE model (Analyze, Design, Development, Implementation, Evaluation) which aims to produce valid and effective science literacy-based teaching aids. The research subjects were fourth grade students at SDN Bandung city. Data were obtained from observations, interviews, questionnaires, expert validation to see the validity of the teaching aids, and test results to see the effectiveness of the teaching aids. The results showed that the average value of the validity of teaching aids by material experts was 96.8% and media experts amounted to 97.9%, while by learning experts amounted to 97.5%. Based on the results of the pretest and posttest, it shows an increase in understanding of the concept of magnetic force after using science literacy-based teaching aids with an average score from 26 to 78 which can be said to be quite effective.
PENGEMBANGAN PERANGKAT PEMBELAJARAN BERDIFERENSIASI SEBAGAI INISIATOR MERDEKA BELAJAR
Authors: Faqih Muhammad Izzatul , Adriyani Zuanita , Muna Khoriyatul
Published: July 2024

AbstractThis research aims to (1) understand the development of differentiated learning tools as initiators of independent learning, (2) assess the feasibility of differentiated learning tools as initiators of independent learning, and (3) determine the effectiveness of learning using differentiated learning tools as initiators of independent learning. The research adopted the Research and Development (RD) methodology, employing data collection techniques such as documentation, observation, interviews, and questionnaires. The research yielded learning tools in the form of Syllabus (RPS), Lesson Implementation Plan (LKM), authentic evaluation instruments, and instruments for learning styles that are highly suitable according to experts. The effectiveness of the tools was evidenced by significantly high scores with a Sig (2-tailed) value less than 0.05. AbstrakPenelitian ini bertujuan untuk (1) Memahami cara mengembangkan perangkat pembelajaran berdiferensiasi sebagai inisiator merdeka belajar, (2) Mengetahui kelayakan perangkat pembelajaran berdiferensiasi sebagai inisiator merdeka belajar, (3) Mengetahui efektivitas pembelajaran menggunakan perangkat pembelajaran berdiferensiasi sebagai inisiator merdeka belajar. Jenis dari penelitian yang dipakai adalah penelitian Research and Developement (RD). Teknik pengumpulan data menggunakan dokumentasi, observasi, wawancara, dan angket. Hasil penelitian perangkat pembelajaran berupa  RPS, LKM, instrumen evaluasi autentik, dan instrumen untuk gaya belajar yang sangat layak digunakan menurut ahli serta perangkat efektiv dengan nilai yang sangat signifikan ditandai dengan skor Sig (2-tailed) kurang dari 0,05.Kata kunci: Perangkat pembelajaran berdiferensiasi; merdeka belajar
Wavelet-based analysis of hydro-climatic and vegetation dynamics in heterogeneous agro-climatic zones of East Africa
Authors: Batungwanayo Pacifique , Vanclooster Marnik , Alonso Alice , Frendy Koropitan Alan
Published: July 2024

Natural and human-induced factors profoundly affect agricultural crop production in East Africa, sparking ongoing debates about their relative significance. This study investigates the impact of localized hydro-climatic variables like precipitation, temperature, vapor pressure deficit, and water deficit on crop production. Additionally, it examines climate oscillations such as El Niño-Southern Oscillation (ENSO), Indian Ocean Dipole (IOD), North Atlantic Oscillation (NAO), and Pacific Decadal Oscillation (PDO). Employing the Normalized Difference Vegetation Index (NDVI) metric, analysis focuses on four climatic zones, ranging from arid to humid. Results suggest that the dominant periodicities for NDVI and hydro-climatic factors are annual (8-16 months) and intra-annual (4-8 months), while circulation indices exhibit inter-annual and inter-decadal periodicity. The study reveals that vegetation dynamics are more sensitive to annual and intra-annual fluctuations in hydro-climatic factors compared to inter-annual and inter-decadal oscillations in circulation indices. The bi-variate wavelet coherence (WTC) analysis reveals that precipitation and ENSO are the most significant factors explaining vegetation variability, while multiple wavelet coherence (MWC) analysis demonstrates that all variables contribute significantly to NDVI variability. This research underscores the importance of wavelet techniques in deciphering complex relationships between hydro-climatic factors and crop production, with implications for agricultural management and policy in East Africa.
Water environment collaborative governance policy in the Yangtze River Delta
Authors: Tian Yuanhong , Bao Cunkuan , Ruth Matthias
Published: July 2024

Water environment collaborative governance is an important policy agenda during the Yangtze River Delta integration. Based on collaborative theory and policy value theory, this essay finds 144 water environment collaborative governance policies in the region from 2007 to 2022. It utilizes a policy collaborative model to discuss the water environment collaborative governance state at the regional and provincial levels in this region. Results show that 87.5% of water environment collaborative governance policies are enacted by local government in the region in this period, the main policy aims of which are water resource protection and wastewater pollution control. More policy attention will need to be paid to water environment restoration and off-office auditing of cadres. While administration policies and legal interventions are the main policy levers, economic policies and personal policies are relatively underused. Policy elements are significantly diversified at the provincial level in the region. In response to the findings above, this essay offers advice to improve water environment collaborative governance in the Yangtze River Delta region on four aspects: giving local governments full discretion in wastewater pollution treatment; giving full play of the water pollution control policies' value; adopting differentiated water pollution control policies; and strategies among the local government in the region, exerting policy stability.
EVALUASI KESESUAIAN LAHAN UNTUK TANAMAN WORTEL (Daucus carota L.) DI KECAMATAN SIRAMPOG KABUPATEN BREBES JAWA TENGAH
Authors: Falahudin Sefa , Nugroho Yudha Sakti , Prastya Rofiq Agiel , Afria Fendra
Published: July 2024

The characteristics and quality of soil can affect the suitability of a land for a certain type of land use. The quality of the soil itself has a close relationship with the characteristics of the land because it has a score weight that affects the suitability of the land. Land characteristics such as slope and land cover affect soil quality such as nutrient content. Erosion calculations using the USLE method show that slope and land cover affect the rate of erosion, where erosion can leach nutrients that result in decreased soil quality. This study aims to determine the suitability of land for carrot plants in Sirampog District. Sirampog District has suitable marginal to suitable temperature, suitable humidity and rainfall, suitable soil texture (loam, sandy loam, and silty loam) relatively low cation exchange capacity (CEC) with very high base saturation, acidic soil pH, medium C-organic, medium N-total, very low P2O5 and very low K2O. This study provided an evaluation of land suitability so that farmers use effective and efficient techniques in cultivating carrot plants, so that carrot crop productivity can be optimal.
PENGARUH PEMBENAH TANAH HAYATI TERHADAP SIFAT KIMIA ENTISOL TERGENANG DAN TIDAK TERGENANG
Authors: Widyantoro Arief , Sambodo Anandeya Satrio , Rahayu Sariman Karta , Supriyanto Supriyanto
Published: July 2024

Farmers began to implement organic systems when the quality of rice fields decreased. Indonesia has several active volcanoes so that the agricultural land was formed by generally Entisols. Several natural and synthetic soil conditioners were starting to be used to decompose the litter and increase the availability of Entisol nutrients. The research aimed to study the effect of providing biological soil amendments on the chemical properties of Entisols. The demonstration plots scale research were used a completely randomized design with a combination of treatments: (P1) Flooded dolomite control, (P2) Non-flooded dolomite control, (P3) Flooded bio soil-neutralizer, and (P4) Non-flooded bio soil-neutralizer. Parameters of soil chemical properties observed were pH, C-organic (%), N-total (%), P2O5-total (%), K2O-total (%), CEC (c mol + kg-1), total bacteria (CFU mL-1), and total fungi (spores g-1). The chemical properties of Entisols before treatment showed slightly acidic pH, low C-organic, low N-total, low K-total, low P-total, and very high CEC. After applying the soil neutralizer, there were an increase in chemical properties including pH becoming alkaline and neutral, medium C-organic, standards to moderat NPK-total, and high CEC. Flooding treatment did not increase the chemical properties of the Entisols.
PEMODELAN SPASIAL DALAM MENGIDENTIFIKASI TINGKAT KERENTANAN BANJIR DI KECAMATAN MEJOBO, KABUPATEN KUDUS, JAWA TENGAH, INDONESIA
Authors: Eka Wulan Safriani  , Somantri Lili , Rohmat Dede , Setiawan Iwan , Panjaitan Budi Rahmah , Arifin A
Published: July 2024

The occurrence of flood disasters is an annual unavoidable event in the Mejobo District, Kudus Regency. This study aims to map the vulnerable areas to floods in the Mejobo District using spatial modelling. The parameters used to determine the vulnerability areas include soil type, elevation, population density, river buffer, rainfall, and land use. The research location is situated in the Mejobo District. The research method employed is the models and multicriteria decision-making (MCDM) techniques, with the assistance of ArcGIS software for data processing and analysis. The research findings yield a final map depicting flood vulnerability, which indicates the distribution of flood-prone areas. Areas with a high level of flood vulnerability are dispersed across agricultural fields and areas adjacent to rivers, covering an area of 1,770 hectares. Meanwhile, areas with a moderate level of vulnerability are predominantly distributed in residential areas, covering an area of 1,907 hectares.
POTENSI LAHAN SAWAH UNTUK PENGEMBANGAN TANAMAN TEMBAKAU DI KABUPATEN BONDOWOSO
Authors: Budiman Subhan Arif , Maulia Dina , Hermiyanto Bambang , Basuki Basuki
Published: July 2024

The plantation sector, especially tobacco plants, is the biggest contributor to the country's foreign exchange value non-mining through tobacco excise and export. With the increasing number of active smokers in Indonesia, the need for tobacco continues to increase, emphasizing the role of this crop in the economy and providing large profits for farmers. However, along with the growing issue of land use change, recently many tobacco plants have been planted on unsuitable land. The research was conducted on all rice fields in Bondowoso Regency from October 2022 to March 2023. The land suitability evaluation method was used to assess land characteristics that affect tobacco plant growth. The parameters used were soil pH, soil texture, C-organic, electrical conductivity, cations bases (K, Ca, Na, Mg), cation exchange capacity (CEC), base saturation, total N, available and exchangeable K, slope, temperature, and rainfall. Data analysis was carried out by matching techniques, namely matching land characteristics with the growing conditions of tobacco plants to get some suitable land suitability classes for tobacco plants. The results of the analysis showed that the area of ​​land currently planted with tobacco reaches about 12,155.06 hectares, with a suitable class (S2) reaching 897.82 hectares, marginal (S3) reaching 1,614.44 hectares, and not suitable (N) reaching 9,642.79 hectares. Land that has the potential to grow tobacco is S2 (quite suitable) and S3 (marginal).
Hypoglycemia in Geriatric Patients with Diabetes: A Review
Authors: Untari Eka Kartika ,   Department of Pharmacy, Medical Faculty, University of Tanjungpura Pontianak, Indonesia, Yuswar Muhammad Akib ,   Department of Pharmacy, Medical Faculty, University of Tanjungpura Pontianak, Indonesia
Published: July 2024

The prevalence of diabetes tends to be high, 42% of geriatric patients admitted have a diabetes diagnosis, and 33% of these patients experience hypoglycemia. Hospitalization is necessary for diabetic elderly individuals because their blood glucose levels make them more vulnerable to other complications. The research aims to examine the frequency of hypoglycemia in older individuals, including those with diabetes, which may be caused by the administration of antidiabetic that lower blood sugar levels. This study is a narrative review of publication that discussed hypoglycemic incidence among geriatrics in PubMed and Google Scholars databases. The type of study included the original article, not the abstract or thesis document from 2016–2021. Sulfonylurea and insulin groups are the most frequently prescribed, and they cause hypoglycemia in diabetic older people, with the rate of hypoglycemic incidence of more than 50%. Other groups of antidiabetes that geriatrics received were alpha-glucosidase inhibitors, dipeptyl peptidase-4, glucagon-like peptide-1, and biguanide, which has been prescribed as monotherapy and combined therapy. The prevalence of hypoglycemic in geriatrics is still present, along with their diabetes medication. For geriatric individuals with DM, routine blood glucose monitoring is advised to prevent diabetic complications.
Hubungan Dukungan Sosial terhadap Kepatuhan Pengobatan Pada Pasien Tuberkulosis di Asia: Tinjauan Naratif
Authors: Kusbandia Kusbandia ,   Mahasiswa Program Studi Magister Manajemen Farmasi Universitas Gadjah Mada, Yogyakarta, Indonesia, A. W Widayanti ,   Fakultas Farmasi, Universitas Gadjah Mada,Yogyakarta, Indonesia
Published: July 2024

Introduction: Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and continues to be a global health concern, particularly in Asian countries. Objective: This narrative review aims to identify the importance of social support in relation to treatment adherence among TB patients in Asia. Methods: The method employed is a narrative review, utilizing the Scopus and Proquest databases from 2017 to 2023 with the same keywords and BOOLEAN operators such as "AND" and "OR." Articles related to adherence, social support, adult TB patients, and research conducted in Asia are included in the study. Results: The results reveal 15 articles related to the relationship between social support and adherence included in this narrative review. Various instruments were used, with some employing existing questionnaires, while others were developed by the researchers themselves. Additionally, some studies did not specifically report the instruments used. Forms of social support provided were utilized as reinforcement in treatment adherence. Conclusion: The forms of social supports, such as emotional, instrumental, and informational support, primarily from family, play a crucial role in TB treatment adherence in Asia.
Resolució anafòrica en traducció automàtica: el cas de l’espanyol i el català
Authors: Alvarez-Vidal Sergi
Published: July 2024

En l'última dècada, la traducció automàtica (TA) ha augmentat la seva presència no només en el sector de la traducció sinó també en el conjunt de la societat, en part pels bons resultats de qualitat obtinguts per la traducció automàtica neuronal (TAN). Actualment, els models massius de llenguatge (MML) com ara GPT (Generic Pre-trained Transformer) poden generar text sobre una infinitat de temes diferents i també traduir documents tenint en compte un context més ampli. Tot i així, per a idiomes estretament relacionats, com ara l'espanyol i el català, la traducció automàtica basada en regles (TABR) s'utilitza diàriament per traduir milers de paraules.
Aquest article estudia la TAN, TABR i GPT del castellà al català, dues llengües romàniques amb una estructura molt semblant en les quals els sistemes de TABR han demostrat un bon rendiment. Utilitzem un challenge test set centrat en la resolució d'anàfores, específicament els pronoms febles, un grup de pronoms que no tenenuna correlació directa entre les dues llengües. Com que els models de TABR només tenen en compte la informació a nivell de frase, només estudiem les aparicions intraoracionals. L'objectiu és avaluar un fenomen sintàctic complex que ens pot ajudar a entendre quin dels tres sistemes tradueix més bé els elements contextuals.
Els resultats mostren que els dos models GPT provats són els que produeixen el nombre més baix d'errors, seguit dels sistemes de TAN. Tot i així, el nombre de traduccions errònies en el millor sistema és del 47%, cosa que contrasta amb els bons resultats d'avaluació generals que s'obtenen per a aquest parell de llengües.
The endogeneity of the natural rate of growth in Latin America
Authors: Ochoa León Sara María , Muller Durán Nancy Ivonne , Rodriguez Benavides Domingo
Published: July 2024

This study estimates the natural rate of growth à la León-Ledesma and Thirlwall for a panel of eleven Latin American countries from 2000 to 2023 using the seemingly unrelated regressions (SUR) estimator. Likewise, in the model, we incorporate a dummy variable in boom periods to determine whether endogeneity is present due to variations in the current rate of growth. Our results show that the behavior of the natural rate has a direct relationship with changes in the current rate; that is, it increases in boom periods and decreases during recessions, confirming the presence of endogeneity. In this sense, it is advisable to continue exploring the nature of the sensitivity of the natural growth rate to the economic situation. By providing recent evidence for Latin American countries with different degrees of economic development, our results allow us to conclude that the hypothesis of full employment on the supply side is not sufficient to explain the economic dynamics, so the inclusion of demand variables is necessary.
Industrialización hacia afuera, balanza de pagos y restricción externa: un análisis para México, 1995-2020
Authors: Landa Díaz Heri Oscar , Cerezo García Verónica
Published: July 2024

El objetivo de esta investigación es examinar el impacto de las características de los patrones de especialización sobre la dinámica industrial, mediante una versión fuerte del modelo de restricción externa de Thirlwall, en 13 subsectores manufactureros de México durante el periodo 1995-2020. Los resultados principales muestran que: i) el crecimiento del sector manufacturero se encuentra restringido por el equilibrio de la cuenta corriente; ii) la elasticidad ingreso de las exportaciones aumenta en la medida que crece la productividad y la acumulación de capital; iii) la elasticidad ingreso de las importaciones es mayor en la medida que aumenta la participación del valor agregado extranjero en la producción de exportación. Con esta evidencia, es posible concluir que la profundización del modelo de industrialización hacia fuera ha limitado las ganancias asociadas al comercio y ralentizado el crecimiento económico. En este contexto, es fundamental operar una política industrial que fortalezca las cadenas de suministro interna y la posición dentro de las cadenas globales de valor. La contribución del trabajo reside en analizar a nivel de subsector las implicaciones de la composición del comercio sobre la expansión económica.
On the Use of a Complex Indicator of the Stability of Permutation Entropy of Time Series Fragments When Analyzing Infrasound Monitoring Signals of the Altai Republic
Authors: Kudryavtsev Nikolay , Frolov Ivan , Safonova Varvara
Published: July 2024

This paper discusses one of the approaches that allows us to assess the degree of complexity or randomness of fragments of a time series in order to detect infrasound or geomagnetic signals in the results of observations of the dynamics of the natural or man-made processes under study. In our case, we are talking about monitoring the infrasound background on the territory of the Altai Republic. To solve the problem of estimating the required characteristics of a time series with minimal computational costs and in real time, a complex indicator of the stability of permutation entropy is introduced, since estimating the value of classical permutation entropy for n = 3 (the most commonly used version of permutation entropy) does not allow solving the problem with sufficient accuracy.
The Wa Concept and its Effects on Deaf Education in Japan
Authors: Dushanta Alyarizki
Published: July 2024

Japanese society has been noted for the emphasis it places on social harmony. As with other cultural values, ideas of harmony may have played a part in written and unwritten rules of the community. As a marginalized group whose existence itself is seen to not be in accordance with the norm, disabled people might particularly be affected by such normative values. This research discusses how values within the wa concept are interwoven in the educational practice for deaf children, as well as the effects it has on them. Values of self-reliance and ‘sameness’ pushes deaf children into assimilation, and to become independent society members that can adapt to the comfort of their surroundings. The deaf education system that has been permeated by the wa concept has resulted in numerous issues, mainly in regards to the childrens’ linguistic skills, as well as social and emotional development. This research shows that while the wa concept is supposed to create societal harmony, normative values created through the lens of the wider and typical society could create a paradoxical situation when applied to marginalized groups such as deaf people.
Application of Financial Engineering in Quantitative Investment Strategy
Authors: Ren Siwei
Published: July 2024

This paper mainly discusses the application of financial engineering in quantitative investment strategy. Firstly, the importance and function of financial engineering in quantitative investment strategy are introduced, and then the principle and technology of quantitative investment strategy are expounded. Then, the application of financial engineering in quantitative investment strategy is analyzed in detail, including stock market analysis, financial risk management, portfolio optimization, market liquidity analysis and financial innovation. Finally, the contribution of financial engineering in quantitative investment strategy and its future development trend are summarized.
A Study on the Sinicization of The Communist Manifesto from the Perspective of Cross-cultural Communication
Authors: Yang Songwo
Published: July 2024

The Communist Manifesto represents Marxism and matters as a source of Communism. Since the first Chinese translation of The Communist Manifesto was published in 1920, there have been 8 translations according to research. This paper expounds changes in the translation of The Communist Manifesto from the perspective of cross-cultural communication, applying an interdisciplinary research method, and combining cross-cultural communication, translation studies and relevant subjects. This paper shows that the translation of The Communist Manifesto gradually indicates Chinese characteristics with the development of times and introduces three means of international communication of Marxism with Chinese characteristics, which is conducive to promoting translation, broadening the field of Marxism works on translations, strengthening ideal and belief of socialism with Chinese characteristics, constructing discourse system of socialism with Chinese characteristics, and enlightening significance for the international communication of Chinese Marxism.
Ecofeminist Awareness and Its Relevance to Sustainable Development: A Study of Chinua Achebe’s Things Fall Apart
Authors: Jahan Israt , Biswas Banani
Published: July 2024

Gender imbalance and environment degradation are two major global concerns today which together form a huge barrier to the sustainability of the Earth’s environment. This paper originates from the contemplation if literature could help raising or enhancing consciousness to prevent those social and artificial ills spread over the world more or less. It studies the synergy between women and ecology found in the prominent cultural postcolonialist Chinua Achebe’s history re-writing novel, Things Fall Apart (1958). It is a widely studied novel focusing mainly on the process and consequence of British colonialism in Nigeria; however, it is indispensable to examine whether its focus on ethnic women and their relation with surrounding ecospheres could provide some in-depth insight into the above mentioned hindrances to sustainable world. Henceforth, the primary objective of this study is to explore how the indigenous beliefs, value system and practices of the Igbo community incorporates ecofeminist awareness, capable of providing some prominent gateways to sustainable development of Nigeria in particular and the world as a whole. The study is entirely qualitative and it employs textual analysis methods to closely examine the narrative and the contexts, i.e., historical, political, and socio-cultural, it is set in. Ecofeminism necessarily provides a comprehensive theoretical framework for the study. However, certain ecowomanist concepts, with particular reference to Alice Walker, are also drawn.
Comparison of Fuzzy Level Set Search and Rescue Optimization and Clustering-Based Segmentation Techniques for Brain Tumor Detection
Authors: Patil Rita B.
Published: July 2024

Abstract: Brain tumor detection is a critical task in medical imaging that requires accurate and efficient image segmentation techniques. This paper presents a comparative study of two advanced segmentation methods: Fuzzy Level Set Search and Rescue Optimization (FLSSRO) and Clustering-Based Segmentation (CBS). By examining the theoretical foundations, algorithmic structures, and performance metrics of these techniques, we aim to highlight their strengths and limitations in the context of brain tumor detection. Through experimental evaluation on benchmark MRI datasets, we analyze the efficacy, accuracy, and computational efficiency of both methods. The study concludes with insights into the appropriate application domains for each technique and potential future research directions.
Peningkatan Kualitas Pemahaman Konten dan Teknik Pengajaran Mata Pelajaran Fisika, Kimia, Matematika, Biologi, dan Teknologi Informasi Komputer (TIK)
Authors: Roniyus Marjunus  , Kamisah Delilawati Pandiangan  , Amanto Amanto  , Mahfut Mahfut  , Yunda Heningtyas  , Heri Satria
Published: July 2024

Background: Pembelajaran Fisika, Kimia, Matematika, Biologi dan Teknologi Informasi-Komputer (TIK) atau disingkat MIPA-TIK di level Sekolah Menengah Atas (SMA) merupakan salah satu bagian dari komponen pendidikan tersebut. Pemahaman yang baik dan benar dari siswa SMA tentang MIPA-TIK diperlukan agar siswa SMA tidak lagi memandang mata pelajaran tersebut sebagai ilmu pengetahuan yang sukar. Oleh karena itu tingkat kualitas pemahaman guru-guru mata pelajaran tersebut di Provinsi Lampung umumnya dan Kabupaten Lampung Selatan khususnya, memegang peranan yang sangat penting. Metode: Evaluasi dilakukan pada awal kegiatan (pre-test) dan akhir kegiatan (post-test) untuk melihat keberhasilan dari kegiatan ini. Hasil: Hasil post-test dibanding pre-test sebesar 45,8%. Kesimpulan: terjadi peningkatan kemampuan atau kompetensi guru-guru dalam menyampaikan materi mata pelajaran tersebut secara baik dan benar.
Pelatihan Penanganan Anak Berkebutuhan Khusus Bagi Guru Sekolah Dasar Muhammadiyah di DKI Jakarta
Authors: Anissa Rizky Andriany  , Dewi Trihandayani  , Anisia Kumala Masyhadi  , Anida Zain  , Ranti Rahmawati
Published: July 2024

Background: Penanganan Anak Berkebutuhan Khusus atau ABK di Indonesia masih menjadi permasalahan tersendiri di dunia Pendidikan. Jumlah ABK yang terus meningkat belum diiringi oleh sumber daya yang memadai dalam proses penanganannya membuat penanganan ABK di Indonesia ini belum maksimal dan turut mempengaruhi efektivitas pembelajaran di dalam kelas. Kegiatan pelatihan ini bertujuan untuk membekali guru dalam menangani Anak Berkebutuhan Khusus di lingkungan sekolah. Metode: Pelatihan ini diikuti oleh tiga puluh guru Sekolah Dasar Muhammadiyah di wilayah DKI Jakarta, yang berada dibawah naungan Majelis Pendidikan Dasar dan Menengah, Pimpinan Wilayah Muhamadiyah DKI Jakarta. Pelatihan yang dilakukan dalam rentang waktu 5 hari pada bulan Januari 2022 ini menggunakan metode pembelajaran orang dewasa dengan pendekatan experiential learning, dan dilakukan dengan metode online melalui platform Zoom Meeting. Hasil: Dari perbandingkan pre-test dan post-test yang diberikan kepada peserta, terlihat adanya peningkatan nilai rata-rata post-test dari nilai rata-rata pre-test. Selain itu, seluruh peserta juga sudah memiliki ketrampilan untuk membuat rancangan program pendidikan anak berkebutuhan khusus di sekolah masing-masing, sesuai dengan kompetensi yang diharapkan dari peserta pada akhir pelatihan ini. Kesimpulan: secara kognitif pelatihan ini dapat meningkatkan pengetahuan peserta setelah mengikuti kegiatan ini