bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the properties of the oral liquid and polymorphism of the MUC5B gene in children with cystic fibrosis
Authors: Nazaryan R. , Tkachenko M. , Volkova N.
Published: April 2020

Investigation of the properties of the oral liquid and polymorphism of the MUC5B gene in children with cystic fibrosis

Nazaryan R., Tkachenko M.,Volkova N.

The article presents the study of biophysical and biochemical properties of saliva and polymorphism of the MUC5B protein gene in children with cystic fibrosis. It has been determined that the development of chronic gingivitis in children with cystic fibrosis occurs of the background of a saliva elasticity increasing and of the salivation rate decreasing. The presence of the allele of MUC5B gene with 9 repeats (59 bp) in the intron 36 in the genotype for cystic fibrosis patients is likely to indicate a lower tendency to gingivitis, while among patients possessing the allele with 6 repeats in the genotype the higher percentage of moderately severe gingivitis was detected. These data could be used to predict the development of chronic gingivitis, depending on the genetic polymorphism of the MUC5B gene and to form risk groups for the purpose of differentiated prescribing preventive and therapeutic measures.

Keywords: children, cystic fibrosis, gene polymorphism, gingivitis, oral fluid.

 

Резюме.

ДОСЛІДЖЕННЯ ВЛАСТИВОСТЕЙ РОТОВОЇ РІДИНИ І ПОЛІМОРФІЗМУ ГЕНУ MUC5B У ХВОРИХ НА МУКОВІСЦИДОЗ ДІТЕЙ

Назарян Р. С., Ткаченко М. В., Волкова Н. Є.

Проведено дослідження біофізичних та біохімічних властивостей ротової рідини та поліморфізму гена білка MUC5B у хворих на муковісцидоз дітей. Визначено, що розвиток хронічного гінгівіту у дітей з муковісцидозом відбувається на тлі підвищення показників тягучості ротової рідини та зниження швидкості слиновиділення. Алельні варіанти кількості повторів 59 п.н. у інтроні 36 гена MUC5B можуть вказувати на схильність пацієнтів до розвитку різного ступеню тяжкості гінгівіту. Результати дослідження можуть бути використані з діагностичною та прогностичною метою і диференційованого призначення профілактичних та лікувальних заходів.

Ключові слова: гінгівіт, діти, муковісцидоз, поліморфізм генів, ротова рідина.

 

Резюме.

ИССЛЕДОВАНИЕ СВОЙСТВ РОТОВОЙ ЖИДКОСТИ И ПОЛИМОРФИЗМА ГЕНА MUC5B У БОЛЬНЫХ МУКОВИСЦИДОЗОМ ДЕТЕЙ

Назарян Р. С., Ткаченко М.В., Волкова Н. Е.

Проведено исследование биофизических и биохимических свойств ротовой жидкости и полиморфизма гена белка MUC5B у больных муковисцидозом детей. Определено, что развитие хронического гингивита у детей с муковисцидозом происходит на фоне повышения показателей тягучести ротовой жидкости и снижения скорости слюноотделения. Аллельные варианты количества повторов 59 п.н. в интроне 36 гена MUC5B могут указывать на склонность пациентов к развитию гингивита различной степени тяжести. Результаты исследования могут быть использованы с диагностической и прогностической целью и дифференцированного назначения профилактических и лечебных мероприятий.

Ключевые слова: гингивит, дети, муковисцидоз, полиморфизм генов, ротовая жидкость.
Diabetes posterior a tratamiento no quirúrgico de un insulinoma maligno: reporte de caso y revisión literatura
Authors: Fierro M Luis F. , Sánchez C Jesús O. , Tapiero G Mireya , Flórez R Andrés , Vargas D Henry , Córdoba C Claudia
Published: April 2020

Los tumores neuroendocrinos pancreáticos (TNEsP) son un grupo poco frecuente de neoplasias, pueden ser funcionales, causando síndromes clínicos diversos, o no funcionales, con síntomas secundarios a invasión a estructuras cercanas o enfermedad metastasica (1). Se presenta el caso de una paciente de 55 años con insulinoma maligno con compromiso metastasico extenso, no candidata a intervención quirúrgica, con hipoglucemia de difícil manejo sin respuesta a tratamiento con diazóxido y prednisolona, que requirió manejo con quimioterapia y embolización de metástasis hepáticas, con posterior mejoría clínica, estabilidad de la enfermedad por imágenes diagnósticas y retiro de medicamentos para manejo hipoglucemia. En seguimiento presenta síntomas de hiperglucemia con HbA1c en 12%, con lo cual se diagnosticó diabetes mellitus de novo y se inició manejo con insulina.
THE EFFECT OF NET HEIGHT SCALING ON STROKE OPPORTUNITY PERFORMANCE IN BADMINTON AMONG CHILDREN
Authors: Henry Kota Pirak , Nazarudin Mohamad Nizam , Suppiah Pathmanathan K.
Published: April 2020

The purpose of this study was to investigate the effect of net height scaling on badminton stroke opportunity performance among children. The study employed the experimental design with repeated measures. Randomly, 48 (n=48) children aged seven to nine years old have been selected to participate in the study. The participants were divided into 24 pairs (boys, n=12, girls, n=12) base on gender and skill level. Participants played four matches in paired with different net height situation, namely situation A (155 cm), situation B (127.66 cm), situation C (117.44 cm), and situation D (104.68 cm). The order of the four conditions counterbalances across the group of participants. All matches played using 11 points of a single game with two sets for every situation. Games performance data was collected via video recording. Data were analyzed using a one-way ANOVA with repeated measures. Mauchly’s Test of Sphericity showed that there are significant differences in terms of stroke opportunity performance [F(2.30, 52.88)=30.37, p<.05]. Based on these results, children who played using modified net height recorded the highest stroke opportunities performance compared with the standard net height situation. This study showed that by manipulating the task constraints through net height scaling, can enhance the stroke opportunity performance among children aged seven to nine years old.
Comparative Global Warming Potential as Environment Protection Criteria of Production Systems: A Case Study of Philippine Chicken Meat Sector
Authors: Espino Ma. Theresa M. , Bellotindos Luzvisminda M. Bellotindos
Published: April 2020

Demand for chicken meat has been increasing tremendously over the years globally at an average 2.4% per annum and in the Philippines at an average of 3.4% per annum. In view of the sustainable development goal (SDG) 13: Climate Change, the chicken meat sector needs to embark on more efficient production. It is not just about producing enough food, but doing it in a sustainable way. This study aimed to demonstrate the identification, evaluation and comparison of the environmental impacts of Philippine chicken meat production systems. The analysis was done through the cradle-to-gate life cycle assessment (LCA) methodology and supported with the global livestock environmental assessment model interactive (GLEAM-i) system. The study evaluated 4 production systems in various sites, namely A: intensive broiler operations; B: small-scale broiler operations with own organic feeds; C: backyard free-range operations with own organic feeds; and D: backyard free-range operations using commercial feeds. Based on a functional unit of 1kg carcass weight (CW), the respective equivalent global warming potential (GWP) were established. System A (5.0 kg CO2-eq kg-1 CW) has the lowest GWP, followed by B (5.15 kg CO2-eq kg-1 CW), D (9.79 kg CO2-eq kg-1 CW) and C (13.51 kg CO2-eq kg-1 CW). Through LCA, the identified improvement opportunities include using locally sourced alternative for feed ingredient for A; increasing production yield to maximize the fixed inputs for B and C; and using locally sourced feed alternatives and increasing production yield for D. Well-established GWP indicators can help in shaping production and consumption patterns. It can help producers in improving operations and in establishing transparency and competitive advantage. While for consumers, it can make them well-informed and empowered in making eco-conscious purchases. This can have a long-term effect on awareness and involvement in environmental protection initiatives among producers, consumers and other concerned groups.
Facial Expression Recognition Based Scoring System for Restaurants using Deep Learning
Authors:   Assistant Professor of GITAM Deemed To Be University, Computer Science and Engineering., K Nagini , D Lakshmidhar Reddy ,   Assistant Professor of GITAM Deemed To Be University, Computer Science and Engineering., M Mokshagna ,   Assistant Professor of GITAM Deemed To Be University, Computer Science and Engineering., B Lohith Kumar ,   Assistant Professor of GITAM Deemed To Be University, Computer Science and Engineering., Tukkoji Chetana ,   Assistant Professor of GITAM Deemed To Be University, Computer Science and Engineering.
Published: April 2020

Now a day, the technology has been increased. Hence this is a tool for the advancement of the earlier things. So we are making use of the technology for restaurant scoring system. The fame of unmanned restaurants is the hot topic in society. Because of the absence of the staff, there is no direct contact with the customers to take feedback of the restaurant. This paper represents the automated rating system for the restaurants by detecting the facial emotions with the help of Convolutional Neural Network [CNN] .It consists of web server and a pretrained CNN and detection of facial expression.
La capitale dell’Ucraina: Kiev o Kyjiv/Kyïv?
Authors: Caffarelli Enzo
Published: April 2020

Alcuni lettori ci chiedono se per indicare la capitale
dell’Ucraina non sia più opportuno adottare la forma in
lingua ucraina (Kyjiv, Kyjiw, Kyïv
nelle traslitterazioni adottate da altri Paesi europei) invece
della forma russa Kiev.
Appropriarsi: transitivo o intransitivo?
Authors: Setti Raffaella
Published: April 2020

Un nostro lettore contesta la costruzione invalsa nell’uso
appropriarsi di qualcosa in luogo di
appropriarsi qualcosa.
Dunoso, dunare o dunale?
Authors: Della Valle Valeria
Published: April 2020

Alcuni lettori ci chiedono se per riferirsi alla duna
costiera sia corretto l'aggettivo dunale o
dunare oppure dunoso: si dice
ambiente, ecosistema dunale, dunare
o dunoso?
Vi rispondiamo… per il giusto tramite
Authors: Giovine Sara
Published: April 2020

Molti lettori ci scrivono per avere delucidazioni sul
corretto impiego della forma tramite: è possibile
utilizzarla con funzione di preposizione o, trattandosi di un
sostantivo, va inclusa all’interno della più ampia locuzione
preposizionale per il tramite di? Ci viene inoltre
chiesto se sia preferibile ricorrere alle preposizioni
mediante e attraverso e quali siano
le eventuali differenze di significato. Infine, qualcuno chiede
se esiste la forma plurale tramiti.
Allo stato, possiamo dare via libera!
Authors: Coletti Vittorio
Published: April 2020

Ci ha scritto un lettore, da Taranto, che sente spesso giornalisti e avvocati utilizzare frasi del tipo: “Allo stato, non risultano prove ...” e ci chiede: “È corretta questa forma? Non è priva di senso? Non si dovrebbe dire allo stato attuale?”.
Non oso o non mi oso?
Authors: Cerruti Massimo
Published: April 2020

Alcuni lettori chiedono informazioni sulla correttezza e sulla caratterizzazione regionale dell’uso di osarsi come verbo pronominale, in costruzioni come non mi oso o non mi oso insistere.
Report di un anglismo
Authors: Di Carlo Miriam
Published: April 2020

Un numero considerevole di lettori ci chiede informazioni sull’anglismo report: dalla pronuncia al genere grammaticale fino alla sinonimia con altre parole italiane tra cui rapporto. Altri lettori ci domandano inoltre se siano in uso i derivati reportare e reportistica. Infine ci viene chiesto quale sia la differenza tra bollettazione e report di magazzino.
Siamo tutti responsabili per o di qualcosa
Authors: Bonomi Ilaria
Published: April 2020

Quale sia la forma da usarsi tra responsabile di e responsabile per costituisce l’oggetto di diversi quesiti sottopostici da lettori. Tra questi, meritano particolare rilievo i quesiti di due lettori, V. A. da Bolzano e R. D. da Vimercate, che oltre a chiedere se sia più corretto responsabile di o responsabile per, notano che in alcuni casi l’uso di per viene più naturale: p.es. "essere responsabile per se stesso" "mi sento responsabile per quanto è accaduto", o anche ipotizzano che ci sia differenza tra “essere responsabili di qualcuno” e “essere responsabili per qualcosa”.
La Crusca risponde ogni tre per due o ogni due per tre?
Authors: Paoli Matilde
Published: April 2020

Molti lettori ci scrivono, specialmente dal Nord Italia, ma anche da Firenze, Roma e Sassari, chiedendo chiarimenti su un modo di dire “numerico”: per significare che qualcosa accade molto spesso si dice che avviene ogni tre per due oppure ogni due per tre? Qual è l’origine di questa espressione? È un modo di dire diffuso da sempre su tutto il territorio nazionale o si è originato in una particolare area?
Una quarantena può durare anche “solo” quattordici giorni
Authors: Tomasin Lorenzo
Published: April 2020

In occasione della drammatica diffusione del coronavirus, sono pervenute in redazione alcune domande che chiedono se sia lecito usare la parola quarantena, che si riferisce a un periodo di quaranta giorni, per il periodo di isolamento di quattordici giorni a cui sono sottoposti coloro che sono stati in contatto con i malati o che comunque sono sospetti di essere stati contagiati.
Sportello del/al/per il cittadino
Authors: Bonomi Ilaria
Published: April 2020

Un interessante quesito ci viene posto dal sindaco del comune di Sernaglia della Battaglia, in provincia di Treviso, teatro di tragici eventi durante la prima guerra mondiale, e insignito dalla Presidenza della Repubblica nel 2009 di una Medaglia d’oro al merito civile per l’esemplare comportamento della popolazione. Il Comune ha istituito uno sportello al cittadino, della cui denominazione si chiede la correttezza linguistica.
Da dove vengono, cosa significano e come si usano sfiga, sfigato e (che) figo/fico
Authors: Loporcaro Michele
Published: April 2020

Un lettore pone un quesito mettendo insieme alcune parole apparentemente tutte connesse: “Mi chiedo perché la parola fico/figo indicante normalmente il frutto dell’albero omonimo (e le grazie femminili se il sostantivo è al femminile […]) abbia assunto la connotazione gergal-giovanile di ‘bello, ganzo, sorprendente’. Come ci si è arrivati? E come si è arrivati ad usare la medesima parola per descrivere un/a bello/a ragazzo/a? E per quanto riguarda la parola sfiga invece?”. Su quest’ultimo termine chiedono spiegazioni anche una lettrice e un altro lettore che ipotizzano una possibile correlazione con il termine gergale fica e/o figa. Su quest’ultimo termine chiedono spiegazioni anche una lettrice (“Vorrei sapere come e da che cosa è nata la parola sfiga, se ha qualche correlazione con il termine gergale fica o figa e se è una parola maschilista”) e, con formulazione sintomaticamente diversa (che qui non riteniamo opportuno riportare per esteso), un altro lettore, il quale chiede se sia “iellato chi non dispone” liberamente del denotato del termine di cui sopra.
Fare un biscotto
Authors: Marzullo Mara
Published: April 2020

Con questa scheda vogliamo riproporre una locuzione usata in ambito calcistico trattata da Mara Marzullo sul n. 29 della "Crusca per voi" (ottobre 2004).
Scendere in campo / mettere in campo
Authors: Piotti Mario
Published: April 2020

Rispondiamo a Fabrizio Gabrielli che, attraverso la nostra pagina Twitter, ci chiedeva un intervento sulle "metafore calcistiche" mettere in campo, scendere in campo. 
L’importante è essere della partita
Authors: Giovanardi Claudio
Published: April 2020

Marco O. da Torino ci scrive sottoponendoci l'espressione, a suo parere abusata, essere della partita molto usata dai commentatori sportivi in luogo di gareggiare o partecipare.
Carlo Negroni dantista e accademico della Crusca
Authors: Marazzini Claudio
Published: April 2020

L’intervento che segue è stato presentato al convegno Da Novara all’Italia. Carlo Negroni (1819-1896) nel bicentenario della nascita, svoltosi presso l’Archivio di Stato di Novara il giorno 11 ottobre 2019. Lo si pubblica qui in omaggio alla figura di un accademico della Crusca oggi ingiustamente dimenticato, e, in prospettiva, in vista delle celebrazioni dantesche del 2021, come segno di rinnovato interessamento per colui che intuì l’utilità della soluzione editoriale per il testo della Commedia di Dante poi adottata da G. Petrocchi.
Lingue: beni collettivi immateriali, che spesso, e per fortuna, si materializzano
Authors: Marazzini Claudio
Published: April 2020

Il giorno 5 di ottobre del 2019 si sono celebrati a Udine i 100 anni della Società Filologica Friulana. Per l’occasione, il presidente dell’Accademia della Crusca, Claudio Marazzini, è stato invitato a tenere una relazione, nel contesto di una serie di interventi rivolti al pubblico che gremiva il bellissimo Salone del Parlamento della Patria del Friuli. Gli atti della giornata saranno pubblicati nella gloriosa rivista “Ce fastu?”. Intanto, però, il prof. Federico Vicario, presidente della Società Filologica Friulana, su richiesta del prof. Marazzini, ha permesso che questo intervento fosse anticipato in una pubblicazione dell’Accademia della Crusca. In questo modo si ribadisce il legame stretto tra le due Accademie, con l’auspicio di una collaborazione fattiva e fruttuosa.
Quando i bruciatai fiorentini divennero buzzurri
Authors: Trifone Pietro
Published: April 2020

Una lettrice ci scrive chiedendoci se sia condivisibile l'etimologia proposta da Francesco Zambaldi nel suo Vocabolario Etimologico Italiano che fa derivare il termine buzzurro dal tedesco Putzer.
Potete contare sulla nostra risposta
Authors: Coletti Vittorio
Published: April 2020

Alcuni lettori chiedono la ragione della differenza nella reggenza preposizionale tra contare su qualcuno e contare su di me, su di te e simili. Altri invece si chiedono che tipo di complemento sia quello retto da contare (su).
Coronavirus Pandemic: Nature Strikes back?
Authors: Ali Shehzad
Published: April 2020

Employing an ontological approach to the coronavirus pandemic, this essay problematizes the relationship between modernity and the Nature. I suggest that the notion of scientific conquest of the Nature is not only flawed, but also counter-productive to our progress. Moreover, I suggest that this notion is adding to the development of the authoritarian state with mass-surveillance infrastructure.
Hyper-Parameter Initialization for Squared Exponential Kernel-based Gaussian Process Regression
Authors: Ulapane Nalika , Thiyagarajan Karthick , kodagoda sarath
Published: April 2020

Hyper-parameter optimization is an essential task in the use of machine learning techniques. Such optimizations are typically done starting with an initial guess provided to hyperparameter values followed by optimization (or minimization) of some cost function via gradient-based methods. The initial values become crucial since there is every chance for reaching local minimums in the cost functions being minimized, especially since gradient-based optimizing is done. Therefore, initializing hyper-parameters several times and repeating optimization to achieve the best solutions is usually attempted. Repetition of optimization can be computationally expensive when using techniques like Gaussian Process (GP) which has an O(n3) complexity, and not having a formal strategy to initialize hyperparameter values is an additional challenge. In general, reinitialization of hyper-parameter values in the contexts of many machine learning techniques including GP has been done at random over the years; some recent developments have proposed some initialization strategies based on the optimization of some meta loss cost functions. To simplify this challenge of hyperparameter initialization, this paper introduces a data-dependent deterministic initialization technique. The speciﬁc case of the squared exponential kernel-based GP regression problem is focused on, and the proposed technique brings novelty by being deterministic as opposed to random initialization, and fast (due to the deterministic nature) as opposed to optimizing some form of meta cost function as done in some previous works. Although global suitability of this initialization technique is not proven in this paper, as a preliminary study the technique’s effectiveness is demonstrated via several synthetic as well as real data-based nonlinear regression examples, hinting that the technique may have the effectiveness for broader usage.
Characteristics of the course of nephritis associated with Iga-vasculitis Henoch-Schoenlein in children
Authors: Sukalo A. V. , Kazyra I. A.
Published: April 2020

INTRODUCTION. Among systemic vasopathies in children, IgA vasculitis Henoch Schoenlein (HS) is the most common, according to various authors, kidney damage is noted in 25-80 % and usually determines the prognosis of the disease.

THE AIM of the study was to analyze clinical, laboratory, immunological, morphological characteristics, features of the course and treatment of nephritis associated with IgA vasculitis HS in children, as well as factors affecting the prognosis.

PATIENTS AND METHODS. The study included 31 patients with morphologically verified nephritis due to IgA vasculitis HS (18 – boys, 13 – girls) aged 3 to 17 years, who were monitored at the Nephrology Department of the "2nd Children's City Clinical Hospital" of the National Center for Pediatric Nephrology and Renal Replacement therapy in Minsk from 2010 to 2019 yrs.The following parameters were analyzed: the clinical variant of kidney damage, laboratory tests (including the study of BAFF, RANTES lymphocyte activation molecules, pro-inflammatory IL1β, caspase1, TNFα, growth factors VEGF, TGF), 24 hours monitoring and office blood pressure measurements, ECHO cardiography with indicescalculation, ultrasound of the carotid arteries with the thickness of intima-media complex, morphological changes in the renal tissue, as well as treatment regimens.

RESULTS. The contribution of deGal-IgA1, markers of T and B lymphocytes activation, pro-inflammatory and profibrotic molecules in the development of the disease is shown. Arterial hypertension was registered in 42 % of children, signs of heart remodeling according to the calculated indices in 19,3 %. Decrease level of adiponectin, vitamin D, leptin, increase concentration of obestatin, Pro-BNP, hs-CRP, and TSAT indicator classify patients with nephritis due to IgA vasculitis HS at moderate risk for the developmentof cardio-vascular disorders, which suggests the need for timely correction.

CONCLUSION. In most cases, nephritis with IgA vasculitis HS has a benign course with rare relapses and progression to the end stage of chronic kidney disease (6,5 %).
Genetic aspects of congenital anomalies of the kidney and urinary tract
Authors: Sukalo A. V. , Kilchevsky A. V. , Mazur O. C. , Sheuchuk I. V. , Mikhalenkо A. P. , Baiko S. V.
Published: April 2020

Congenital anomalies of kidney and urinary tract (CAKUT) constitute an average of 25 % of the total number of all genetic anomalies diagnosed in utero and include both individual anomalies of kidney or urinary tract and a combination of such. One of the important problems of pediatric nephrology is the early diagnosis of congenital anomalies of kidney and urinary tract, since untimely detected pathologies lead to a decrease in renal function. The cause of such violations can be genetic factors, environmental factors affecting the woman's body before or during pregnancy. Genetic factor contributes significantly to the formation of CAKUT based on the proven role of mutations in more than 200 genes associated with the development of these anomalies. Since the classical methods of molecular diagnostics do not allow in 90 % of cases to determine occurring mutations, there is a need to apply new genetic testing technologies to identify mutations of genes associated with this group of diseases. Next generation sequencing allows to detect rare genetic variants and concurrently test a large number of genes within a short period of time for the presence of clinically important mutations in them. In addition, the use of next-generation sequencing expands the search for new candidate genes of CAKUT. There are ethnic differences regarding genes involved in the development of congenital anomalies of kidney and urinary tract. The most promising present-day strategy is based on the study of the specific region of patient’s whole exome and the subsequent development of a diagnostic panel.
Nephrology association round table
Authors: Editorial Article
Published: April 2020

.
I.P. Pavlov in life and russian art of the XX century. (Тo the 170-th anniversary)
Authors: Parastaeva M. M. , Beresneva O. N.
Published: April 2020

The work is dedicated to the 170th anniversary of the outstanding physiologist I.P. Pavlova. Reflected some points of his scientific activities and biographies. Particular attention is paid to the image of I.P. Pavlova in the works of Russian artists and sculptors – contemporaries of the scientist.
THE WORK «ASOSU-L-BALOG‘A» BY MAKHMUD ZAMAXSHAR’I IS AS SOURCE OF PHRASEOLOGY
Authors: Nigora SULAYMONOVA
Published: April 2020

This article provides an overview of the phraseology used by Makhmud Zamaxshar’i in his dictionary work "Asosu-l-balog‘a" as illustrative material to define headwords in dictionary articles. The article is separated and analyzed phraseologies which are used in the "Asosu-l-balog‘a" according to the types.

KEYWORDS: "Asosu-l-balog‘a", defining dictionary, glossary article, headword, illustrative material, phraseology, phraseological fusion, phraseological unity, phraseological combination (collacation).
Cutaneous Mastocytosis in a 61-year-old Female from a Dermatological and Histopathological Perspective
Authors: Erisa Kola  , Jorida Memini  , Ina Kola  , Daniela Nakuci  , John Ekladous  , Denisa Cipi  , Migena Brati Dervishi
Published: April 2020

First described by Nettleship et al. in 1869 [1], mastocytoses are a heterogeneous group of disorders characterized by the pathologic accumulation of mast cells in various tissues [2-5]. Mastocytosis can be confined to the skin as in cutaneous mastocytosis (CM), or it can involve extracutaneous tissues such as the liver, spleen, bone marrow and lymph nodes, as in systemic mastocytosis [6]. Mastocytosis is a World Health Organization-defined clonal mast cell disorder characterized by significant clinicopathologic heterogeneity [7].

Keywords: Cutaneous mastocytosis; Systemic mastocytosis; Systemic involvement; Mast cells; Mastocytosis.
PENDIDIKAN ISLAM DALAM PERSPEKTIF EPISTEMOLOGI BURHANIY
Authors: Abdur Rohman Muhamad Asvin
Published: April 2020

Soebardi in The Place of Islam states that: (a) institutions boarding schools are the institutions most decisive Islamic character of Islamic kingdoms and the most important role for the spread of Islam to the outposts; (B) of the institutions of boarding that origins a number of manuscripts concerning the teaching of Islam in Southeast Asia, (c) and to be able to truly understand the history of Islamization in the region, we should begin to study these boarding institutions, because tutions is the primary agency arrows spread of Islam in the region. Pesantren education today can be classified into three types. First, the boarding school education and teaching how to use the method sorogan or dam, which is a teaching Kyai of santri based on the classic books written in Arabic, by scholars' medieval translation system. Generall, boarding school is "stiril" of general science. People usually call it by name salaf pesantren. Second, in addition to maintaining the boarding school and teaching systems, as mentioned above, also includes public education. Third, schools as the education system and teaching models integrates into schools with one the soul, and the value of other attributes, and teaching wear classical system coupled with strict discipline with full dormitories or students are required to reside in the hostel. The specific objective education pesantren is to prepare the students to become people 'alim in the science of religion taught by clerics concerned and put it into practice in the community. While the general purpose schools is to guide students into human personality capable of Islam with religious knowledge became muballig in the surrounding communities through science and charity.
Perjalanan Haji Indonesia di Masa Kolonial
Authors: Rohmatulloh Dawam Multazamy
Published: April 2020

Hajj or pilgrimage is one of the important worship activities for Indonesian Muslims since past. Based on colonial archives, this paper describes thedynamics of the pilgrimage of Indonesia in the colonial period. The long duration of the trip, a tough challenge, and the high cost of travel is a “fee” to be paid by the pilgrims in the past. Moreover, the existence of many service provider of the pilgrimage also influence that dynamics. On the other hand, the colonial government also plays an important role by issuing a variety of regulations to ensure the “order” of the pilgrimage.

Keywords: Hajj trip, company, regulation, colonial period.
Analisis Perbandingan Teknik 3D Rendering Cycles Dan Eevee Pada Software Blender
Authors: Aryanto Aryanto , Hisyam Muhammad Umar Tengku , Winarso Doni
Published: April 2020

Penelitian ini membahas tentang menganalisis perbandingan teknik rendering tiga dimensi antara render Cycles dengan render Eevee yang ada didalam perangkat lunak opensource Blender 3D. Hasil pengujiannya akan membantu setiap CG Artist atau pengguna aplikasi tiga dimensi dalam memilih render engine yang cocok untuk karya atau 3D Artwork yang mereka kerjakan. Teknik render yang dianalisis yaitu Cycles yang merupakan jenis render engine pre-rendered yang proses rendernya bisa menghabiskan waktu lama karena pemrosesannya yang rumit, kemudian Eevee merupakan real-time render yang proses render-nya sendiri tidak begitu membutuhkan waktu yang lama, karena prosesnya sendiri dilakukan secara realtime. Vertices dan Texture digunakan sebagai parameter pengukuran untuk pengujian kedua teknik rendering. Analisis perbandingan Cycles dan Eevee akan menghasilkan pengujian kecepatan render, ukuran file hasil render, dan kualitas gambar dari hasil render. Hasil dari penelitian ini mampu menyatakan bahwa Eevee mengungguli Cycles dalam dalam perbandingan kecepatan rendering, Cycles dan Eevee pada output hasil render tidak jauh berbeda ukuran file-nya, dan kualitas gambar dari render menyatakan Eevee lebih unggul dibandingkan Cycles.
Rancang Bangun Sistem Informasi Penerimaan Peserta Didik Baru Berbasis Web Pada SDIT Al-Manar Kota Pekanbaru
Authors: Angraina  Fitri Diah , Sulistio
Published: April 2020

SDIT Al-Manar Kota Pekanbaru merupakan sebuah sekolah dasar swasta yang berada di kota Pekanbaru, Riau. Setiap memasuki Tahun Pelajaran baru SDIT Al-Manar selalu membuka penerimaan peserta didik baru, yang mana dalam pelaksanaan PPDB ini masih dilakukan dengan cara manual sehingga dirasa belum efektif dan efisien. Dengan semakin berkembangnya dunia komputerisasi terkhususnya dalam penggunaan sistem informasi berbasis web diharapkan dengan ini dapat membantu orang tua calon siswa dalam melakukan pendaftaran dan mendapatkan informasi mengenai PPDB dan juga dapat membantu panitia PPDB dalam mengelola data calon siswa sehingga dapat mengetahui keefektifan dari sistem ini. Metode yang dipergunakan dalam penelitian ini adalah wawancara, observasi, studi pustaka, perancangan sistem, uji coba dan implementasi. Dari penelitian ini diharapkan sistem informasi yang dibuat dapat memberikan kemudahan dalam pelaksanaan penerimaan peserta didik baru di SDIT Al-Manar Kota Pekanbaru
Perancangan Aplikasi Pariwisata Kuantan Singingi Berbasis Android Menggunakan Push Notification Dan LBS
Authors: Candra Feri , Ramadhan
Published: April 2020

Kuantan Singingi merupakan salah satu Kabupaten di Provinsi Riau yang dikunjungi banyak wisatawan setiap tahunnya, hal ini dikarenakan terdapat sebuah event tahunan yang digelar oleh pemerintah yaitu pagelaran 'Pacu Jalur' yang saat ini sudah masuk dalam Kalender Pariwisata Nasional. Banyaknya wisatawan yang datang ke Kuantan Singingi membuat kebutuhan akan informasi pariwisata di Kuansing meningkat, oleh karena itu tujuan dari penelitian ini adalah untuk mengembangkan aplikasi pariwisata berbasis android menggunakan Push Notification dan Layanan Berbasis Lokasi. Tahapan perancangan aplikasi pariwisata ini menggunakan metode Waterfall. Penelitian ini menghasilkan Aplikasi Wisata Kuantan Singingi yang berbasis Android yang dapat digunakan  untuk membantu wisatawan yang dibuktikan dengan hasil persentase sebesar 87.2% dengan kategori 'Sangat Memuaskan' dan membantu pemerintah mempromosikan pariwisata Kuansing yang dibuktikan dengan hasil persentase sebesar 87.5% dengan kategori 'Sangat Memuaskan'.
Modified SCA algorithm for SSSC damping Controller design in Power System
Authors: Rout Bidyadhar , Pati B.B. , Panda S.
Published: April 2020

This paper studies the improvement of transient stability of a single-Machine Infinite-Bus (SMIB) power system using Proportional Derivative (PD) type Static Synchronous Series Compensator (SSSC) and damping controllers. The design problem has been considered as optimisation problem and a modified version of recently proposed Sine Cosine Algorithm (SCA) has been employed for determining the optimal controller parameters. Proposed modified SCA (mSCA) algorithm is first tested using bench mark test functions and compared with SCA, and other heuristic evolutionary optimization algorithms like Grey Wolf optimization (GWO), Particle Swarm optimization (PSO), Gravitational Search algorithm (GSA) and Differential Evolution algorithm to show its superiority. The proposed mSCA algorithm is then applied to optimize simultaneously the PD type lead lag controller parameters pertaining to SSSC and power system stabilizer(PSS). The proposed controller provides sufficient damping for power system oscillation in different operating conditions and disturbances. Results analysis reveal that proposed mSCA technique provides higher effectiveness and robustness in damping oscillations of the power system and increases the dynamic stability more.
Thyristor Controlled Series Compensator based Optimal Reallocation of Generators for Contingency Management
Authors: Kumar B. Sravana , Suryakalavathi M. , Kumar G.V.Nagesh
Published: April 2020

Privatization of the power industry has made proper utilization of the available resources a compulsory requirement. Optimal power flow (OPF) is an ideal solution to the problem. At the same time, stable operation of the power systems in both normal and contingency condition is of vital importance. Use of FACTS devices is a good method to stop further contingencies in the power system. In this paper, a combined index based strategy for the optimal placement of Thyristor Controlled Series Compensator (TCSC) and optimal tuning of generators using Krill Herd Algorithm has been proposed for contingency management. The contingency analysis has been done using a new method, namely, rapid contingency ranking technique (RCRT). The TCSC has been placed on the basis of an index which is a combination of Line Utilization Factor (LUF) and Fast Voltage Stability Index (FVSI). A multi-objective function has been chosen for tuning the generators. The multi-objective function includes voltage deviation, active power generation cost and transmission line loss.  The proposed method has been tested and implemented on an IEEE 30 bus system.
Privatization of the power industry has made proper utilization of the available resources a compulsory requirement. Optimal power flow (OPF) is an ideal solution to the problem. At the same time, stable operation of the power systems in both normal and contingency condition is of vital importance. Use of FACTS devices is a good method to stop further contingencies in the power system. In this paper, a combined index based strategy for the optimal placement of Thyristor Controlled Series Compensator (TCSC) and optimal tuning of generators using Krill Herd Algorithm has been proposed for contingency management. The contingency analysis has been done using a new method, namely, rapid contingency ranking technique (RCRT). The TCSC has been placed on the basis of an index which is a combination of Line Utilization Factor (LUF) and Fast Voltage Stability Index (FVSI). A multi objective function has been chosen for tuning the generators. The multi-objective function includes voltage deviation, active power generation cost and transmission line loss.  The proposed method has been tested and implemented on an IEEE 30 bus system.
On the Performance of the Layered-Division-Multiplexing using Maximal-Ratio Combining
Authors: Khumyat Tanapong
Published: April 2020

This article proposes the diversity gain enhancement in layered division multiplexing (LDM) systems by applying maximal-ratio combining (MRC) technique. LDM systems is adopted as a baseline technology of the ATSC 3.0 systems which the two transmission layers are simultaneously transmitted over two different types of fading channels for fixed and mobile services. Hence, the performance analysis of each layer need to be evaluated on different type of fading channel. Starting with the moment generating function (MGF) of the MRC output signal-to-noise ratio (SNR), we propose the new method to derive closed-form expressions for average symbol-error rate (SER) of the proposed systems over Rayleigh and Nakagami-m fading channels in the presence of error propagation (EP) that is generated from the first layer detection. Analytical results show that the specific value of injection level at the transmitter need to be precisely defined to obtain the best mutual benefit for both LDM layers, and the proposed technique has significant performance advantage over conventional LDM systems. Simulation results demonstrate the tightness of the author’s analysis.
Performance Analysis Methods in Smart Grids: An Overview
Authors: Salkuti Surender Reddy
Published: April 2020

This paper presents an overview of the performance analysis methods available for the Smart Grid (SG). Increased energy demand, volatile energy costs, uncertain power generation from the renewable energy resources (RERs), electric vehicles, and environmental concerns are coming together to change the nature of the traditional power grid. Many utility companies are now moving towards the smart metering and the Smart Grid solutions to address these challenges. Smart Grid is inclusive of advance tools, latest communication technologies and storage devices, which makes the Smart Grid vulnerable and complex. This paper aims to review the performance analysis of Smart Grid. It also presents various models of the Smart Grid performance indices. It presents the methods available for stability, reliability and resilience assessment in Smart Grid. It also describes the implementation approach using the real time tools and techniques.
O HOMESCHOOLING E AS DISCUSSÕES ENTRE A NECESSIDADE FAMILIAR E A LEGISLAÇÃO
Authors: César Dias Lopes Gabriel
Published: April 2020

Este artigo discute, a importância e as implicações da educação domiciliar como um ensino individualizado para o desenvolvimento   aprendizagem da criança. Nele é explicitado o motivo pelo qual as famílias optam por esse método de ensino. No Brasil era um  ssunto que pouco se discutia, mais a cada dia vemos que essa barreira do silêncio está sendo quebrada e o tema tornou-se mais  vidente, tanto que, mesmo com as dificuldades, já se estima um número elevado de adeptos em todo o país. Também é apresentado   esclarecido o significado de educar os filhos em casa, como isso ocorre, e a situação jurídica brasileira diante da  uestão, análises e outros aspectos que envolve a educação domiciliar, como a importância da família para o desenvolvimento  ognitivo da criança e as discussões e impasses acerca da socialização escolar.
BIPOLARIDADE X TRANSTORNO DISSOCIATIVO DE PERSONALIDADES MÚLTIPLAS :DIFERENÇAS ALÉM DA SEMÂNTICA
Authors: César Dias Lopes Gabriel
Published: April 2020

Este artigo caracteriza e discute as diferenças entre a bipolaridade e o transtorno dissociativo de personalidades múltiplas, abordando-as como fatores de preocupação para a saúde pública por conta dos transtornos e prejuízos causados ao indivíduo e ao seu entorno e de sua etiologia que envolvem aspectos neuroquímicos, cognitivos, psicológicos, funcionais, familiares e socioeconômicos, enfatizando a teoria de Vygotsky para ressaltar a importância do fator emocional para o desenvolvimento dessas patologias. Para tanto utilizou-se aqui a pesquisa bibliográfica enquanto metodologia dentro de uma abordagem qualitativa e descritiva; Foram usados os bancos de dados de revistas eletrônicas como Scielo, PubMed, Redalyc Considerase finalmente aqui sob o ponto de vista semântico e terapêutico o transtorno bipolar, em sua predisposição genética, considerando aqui os diversos fatores que podem alterá-lo ou agraválo, sendo eles socioambientais, psicológicos, buscando ressaltar as formas de acompanhamento possíveis desde o medicamentoso até o psicanalítico, valorizando o aspecto do apoio familiar notadamente fundamental para o paciente.
Ukrainian experience of personnel vocational training: problems and prospects
Authors: Krupskyi Oleksandr, , Ivankiva Vladislava,
Published: April 2020

A critical analysis of the Ukrainian experience of vocational training of personnel is conducted in the work. The statistics data on the number of employees who participated in vocational training activities during 2016-2018 are presented and analyzed. Based on the analysis, the main reasons for the low interest of Ukrainian business owners in the personnel vocational training were identified. In the work, the author also has highlighted the factors that restrain and activate the development of vocational training of personnel at Ukrainian enterprises. In order to increase the efficiency of professional development of personnel at Ukrainian enterprises, the author proposes to use modern methods for this purpose. Because traditional methods do not produce the desired results. Ukrainian enterprises need to invest in staff training, which is the main reserve for improving their performance.
The expediency of identifying strategic alternatives to the development of the state's economic security system through SWOT analysis
Authors: Loishyn Anatolii, , Tkach Mykola, , Levchenko Sergey, , Getmanskii Vitalii, , Parhomenko Pavlo,
Published: April 2020

The outcomes of the conducted research presented in the article will be valuable for managers of all levels involved in strategic planning and management of the modern economy of the state. The article addresses the urgent issue of identifying certain strategic alternatives in the development of the state's economic security system. The analysis of existing threats to the economic security of the state is conducted; the approaches to the definition of economic security are analyzed. The study emphasizes the complex political, social and economic situation in Ukraine due to the difficult situation in eastern Ukraine and the temporary occupation of the Republic of Crimea. It draws attention to the place of Ukraine in the ranking of international organizations and provides information on the main forecast macroeconomic indicators of economic and social development of Ukraine for 2020-2022. It is determined that the economic security of the state is based on self-sufficiency, stability and development of all constituent elements of the economy, and their list is given. The article emphasizes the priority development of the economic security system in the conditions of continuous improvement of the scientific and technical market, constant modernization of production, development of educational institutions, creation of a favorable climate for investment, significant state support of innovative activity. The possibility of using SWOT analysis as a tool for determining strategic alternatives has been investigated and confirmed. The article analyzes information and gives a detailed description of the elements (components) of SWOT analysis. The algorithm of estimation with use of SWOT analysis is graphically presented. The method of carrying out SWOT analysis with corresponding detail of each stage is presented. The study identified and analyzed the advantages and disadvantages of using SWOT analysis in comparison with other methods.
Benchmarking and effective strategic communications: ways to implement in public administration
Authors: Izhutova Iryna,
Published: April 2020

The current information environment is being extremely fast developed mixing up and joining public administration and commercial (private) sector. The article discusses benchmarking, including a proposal to implement benchmarking as measurement of effectiveness of realization of the strategic communications in public administration.
Struggle against financing terrorism in the world and Ukraine by the way of strengthening the state financial control and audit system
Authors: Tkach Mykola , Biliuha Andrii , Holota Olena , Parkhomenko Pavlo , Gannenko Yuri
Published: April 2020

As the title implies the article describes essential world problem – financing of terrorism. It is specially noted the role state finance control in the preditictions of financing of terrorism.

During the 21st century the topic of terrorism has become one of the most dangerous and large-scale global challenges to the world community. Since the events of September 11, 2001 in the United States of America, the phenomenon of terrorism has become more violent, bloody and cynical. The number of states that have experienced the horrific consequences of acts of terrorism is on the rise, and in turn, bears human toll, destruction of infrastructure, intimidation of people and more.

The article shows how terrorist organizations are adapting to the current situation and finding new methods and ways of meeting their specific goals with the use of different sources of funding, and what the methods of counteracting them in international practice and in Ukraine.

Also, It draws our attention to to analyze the notion of terrorist financing and international experience in opposing it.

Much attention is given to analyze the manifestations of terrorist financing in Ukraine.
Climate Change and Nutrition
Authors: Kelly Niamh
Published: April 2020

Human health and planetary health are intertwined in many ways, food systems being an example. This article describes the complex manner in which food systems impact the environment and how our dietary choices have consequences for climate change. Subsequent changes to weather patterns and ecosystems can then destabilise these food systems impacting on human health. This article explains how various components of food systems must be considered when attempting to understand the effects on climate change. It concludes by offering practical solutions on an individual and societal level to mitigate these effects.