bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of pretransplant use of tyrosine kinase inhibitors on allogeneic stem cell transplantation in patients with chronic myeloid leukemia - A single-institution retrospective study
Authors: Fujita Shinya , Sakurai Masatoshi , Kasahara Hidenori , Kato Jun , Koda Yuya , Yamaguchi Kentaro , Shiroshita Kohei , Okayama Mikio , Abe Ryohei , Kikuchi Taku , Shimizu Takayuki , Mori Takehiko , Kataoka Keisuke , Okamoto Shinichiro
Published: September 2022

Second- and third-generation (2/3G) tyrosine kinase inhibitors (TKIs) possess excellent treatment effects on chronic myeloid leukemia (CML), and at least one 2/3G TKI is mostly incorporated into the first treatment of CML in all phases. However, the impact of 2/3G TKIs on subsequent allogeneic stem cell transplantation (allo-SCT) remains to be elucidated. We retrospectively evaluated how pretransplant therapy with TKIs affects the outcome of allo-SCT for CML using the clinical data of thirty-two patients with CML transplanted between 2001 and 2020 at our institution. Except for 11 patients who remained in the chronic phase (CP) until the time of allo-SCT, 10 patients were initially diagnosed with accelerated or blastic phase (AP/BP), and 11 patients progressed to AP/BP during the treatment for CP. With subsequent use of 2/3G TKI or imatinib (IM), 10 and 4 patients returned to the second CP at the time of allo-SCT, respectively. In univariate analysis, pretransplant use of 2/3 GTKI was significantly associated with higher 5-year overall survival (91.7%) and relapse-free survival (75.0%) than the use of IM (37.5% and 12.5%, respectively) in patients presenting with or progressing to AP/BP before allo-SCT. Our results suggest that pretransplant use of 2/3G TKI improves the outcome of allo-SCT in CML patients who present with AP/BP at diagnosis or progress to the advanced phase thereafter.
Metataxonomic Analysis of Feces from Older Adults with and without HIV Title 2: Aging, HIV, and Gut Dysbiosis
Authors: Sánchez-Conde Matilde , Alba Claudio , Castro Irma , Dronda Fernando , Ramírez Margarita , Arroyo Rebeca , Moreno Santiago , Rodríguez Juan Miguel , Brañas Fátima
Published: September 2022

Background: HIV infection has been postulated as a model of accelerated aging. Previous studies have suggested a link between aging, frailty, and gut dysbiosis, but there is a knowledge gap in this field regarding the HIV population. Our objective was to explore the gut dysbiosis in older people with HIV (PWH) compared to non-HIV controls and to assess its possible link with frailty.
Methods: A total of 36 fecal samples were submitted to a metataxonomic analysis. 24 were from PWH > 55 years and the other 12 were non-HIV healthy controls.
Results: Alpha diversity was significantly higher in the control group than in the HIV group (Shannon index,3.74 [3.65-3.94] and 3.56 [3.32-3.69]], respectively; p < 0.05). At the genus level, the relative abundance of the genus Blautia was higher in the HIV group. Presence of Blautiawas also higher in PWH patients with depression, whereas the contrary was observed for the genus Bifidobacterium.
Conclusions: Our study shows significant shifts in the composition of the bacteriome of PWH when compared to that of healthy controls. To our knowledge, this is the first study suggesting a potential link between depression and gut dysbiosis in the HIV population.
Hybrid COOT–ANN: a novel optimization algorithm for prediction of daily reference evapotranspiration in Australia
Authors: Mirzania Ehsan , Kashani Mahsa Hasanpour , Golmohammadi Golmar , Ibrahim Osama Ragab , Saroughi Mohsen
Published: September 2022

The present study evaluates the capability of a novel optimization method in modeling daily reference evapotranspiration (ET0), a critical issue in water resource management. A hybrid predictive model based on the ANN Algorithm that is embedded within the COOT method (COOT bird natural life model- Artificial Neural Network (COOT-ANN)) is developed and evaluated for its suitability for the prediction of daily ET0 at seven meteorological stations in different states of Australia. Accordingly, a daily statistical period of 12 years (01-01-2010 to 31-12-2021) for climatic data of maximum temperature, minimum temperature, and ET0 were collected. The results are evaluated using six performance criteria metrics: correlation coefficient (R), Root Mean Square Error (RMSE), Nash-Sutcliffe efficiency (NSE), RMSE-observation standard deviation ratio (RSR), Scatter Index (SI), and mean absolute error (MAE) along with the Taylor diagrams. The performance of the COOT-ANN model was compared with those of the conventional ANN model. The results showed that the COOT-ANN hybrid model outperforms the ANN model at all seven stations; and so this study provides an innovative method for prediction in agricultural and water resources studies.
Otolith morphological study and biometric analysis of two hermaphrodite species Sarpa salpa and Serranus scriba (Linnaeus, 1758) in Bizerte Sea
Authors: Bakkari Wided , Mejri Marwa , Chalh Abdellah , Quignard Jean-Pierre , Trabelsi Monia
Published: September 2022

In this study two hermaphrodite species samples of Bizerte sea.In order to compare the morphological variability (Fourier coefficients) and biometric charcaters (length, width, area and otolith perimeter). The result show a significant results that are clearly demonstrated by an asymmetry when comparing otoliths (P < 0.05) for S.scriba and for S.salpa showed a symmetry (P = 0.056).However for biometric comparison, between the rigth and left otoliths for each population, we detected a highly difference between otolith in all the parameter of S.salpa . All these difference existing between the two species can be related to the environmental specificity and stress. In addition, asymmetry in width character is could be explained by the vulnerability of this trait to immediate changes in environmental factors.
Photothermally induced natural vibration for versatile and high-speed actuation of crystals
Authors: Hagiwara Yuki , Hasebe Shodai , Fujisawa Hiroki , Morikawa Junko , Asahi Toru , Koshima Hideko
Published: September 2022

The flourishing field of soft robotics requires versatile actuation methodology. Natural vibration is a physical phenomenon that can occur in any material. Here, we report high-speed bending of anisole crystals by natural vibration induced by the photothermal effect. Rod-shaped crystal cantilevers undergo small, fast repetitive bending due to natural vibration accompanied by large photothermal bending under ultraviolet light irradiation. The natural vibration is greatly amplified by resonance upon pulsed light irradiation at the natural frequency to realise high frequency (~ 700 Hz), large bending, and high energy conversion efficiency. The natural vibration is induced by the thermal load generated by the temperature gradient in the crystal due to the photothermal effect. The bending behaviour is successfully simulated using finite element analyses. Any light-absorbing crystal can be actuated by photothermally induced natural vibration. This finding of versatile crystal actuation can lead to the development of soft robotics.
How Do Supporters Respond When Mentioned on Twitter by a Political Elite? Examining the Impact of Prime Minister Narendra Modi’s Tweets in the 2019 Indian General Election
Authors: Neyazi Taberez Ahmed , Ee Tan Khai , Haque Mohammad Amaan
Published: September 2022

Does interactivity on Twitter initiated by political elites yield dividends in terms of indirect outcomes such as online political mobilization? Twitter has traditionally been utilized by political elites mainly as broadcasting media, characterized by its limited interactions with the wider public. In doing so, political elites may be overlooking Twitter's utility as an interactive media for mobilizing their supporters, which we seek evidence for in this paper. We adopt a naturalistic quasi-experimental design utilizing a unique dataset comprising tweets of users who were mentioned (36.62 million tweets) and not mentioned (29.73 million tweets) by Prime Minister Narendra Modi on 16th March, 2019 during his general election campaign. A controlled intervention analysis using Autoregressive Integrated Moving Average (ARIMA) models was carried out, which suggests that, on average, the total tweets count increased more for users mentioned by Modi (treatment group) as compared to those not mentioned by Modi (control group). However, no substantive lasting effect could be detected, indicating therefore that a mention by political elites helps generate immediate engagement which is not necessarily self-sustaining. To determine if this activation behavior is more prominent for less or more active users, we categorized the users based on their Twitter activity and assessed the significance of any movement between categories; no evidence could be found in support of this claim. Our findings thus provide important insights to understand how Twitter can be used as an effective platform for political campaigns by exploiting some of its interactive features such as replies and mentions to mobilize supporters.
Self-serving Regret: Experimental Evidence from a Reciprocity Game
Authors: Lian Zeng , Shen Xin , Zheng Jie
Published: September 2022

Self-interested behavior has been well identified in dictator games: people allocate little or nothing to serve their interests better. Although it has long been recognized that beliefs about others are critical in interpersonal interactions, the mechanism by which self-serving beliefs result in self-serving behavior remains unclear. To explore the relationship among the conflict of interest, belief formation, and the resulting behavior, this study designed a three-stage reciprocity game with belief elicitation and regret option and conducted a laboratory experiment using university students as the subject pool. By asking recipients to predict the allocators' decisions and incentivizing the prediction, we discover that people rationalize their own self-serving bias by believing that others are similarly self-interested and then returning the 'favor' in the name of fairness. Additionally, this study examined post-decision regret by the reciprocators, and the asymmetry between upward and downward adjustments indicates a self-serving pattern: Reciprocators who under-estimated the allocated amount are less likely to make an upward adjustment compared to the likelihood of downward adjustment made by those who over-estimated the allocated amount. This study contributes to the literature on self-serving bias by better understanding the presence of self-serving beliefs and self-serving behavior.
Investigation on the characteristics of inserts supporting run-flat tire blowout under typical driving conditions considering the camber angle
Authors: Wang Xingyu , Zang Liguo , Lv tian , li Yaowei
Published: September 2022

Run-flat tires are an important solution to solve the traffic accidents of tire blowout and the inserts supporting run-flat tire (ISRFT) can effectively solve the problem of zero-pressure driving after the tire blowout. Since the characteristics of vehicles equipped with this run-flat tire after tire blowout is different from that of normal tires, a reasonable tire model is required to develop the dynamic response characteristics. In this paper, the theoretical analysis of the zero-pressure rolling for the inserts supporting run-flat tire was firstly carried out, and steady-state mechanical characteristics tests were conducted to obtain the mechanical characteristics. Secondly, a dynamics model based on the UniTire model was developed for inserts supporting run-flat with the consideration of camber angle.Finally, three sets of typical working conditions were selected to compare the effect of different camber angles on the tire blowout parameters of vehicles equipped with inserts supporting run-flat tire and normal tire (NT), which proved the superiority characteristics of inserts supporting run-flat tire. This study provides a basis for improving the autonomous characteristics of vehicles.
Cardiac Morphology in Neonates With Fetal Growth Restriction
Authors: Bjarkoe Lisa , Fugelseth Drude , Haugen Guttorm , Kiserud Torvid , Harsem Nina , Nestaas Eirik
Published: September 2022

Objective: Assess effects of fetal growth restriction (FGR) on cardiac modelling in premature and term neonates.
Study design: Prospective echocardiographic cohort study comparing FGR neonates (n=21) and controls (n=41) with normal prenatal growth and circulation.
Results: Unadjusted for gestational age, birth weight, sex and twin/singleton, Late-FGR neonates had smaller hearts than controls, with globular left ventricles and symmetrical right ventricles. Adjusted estimates showed smaller left ventricles and similarly sized right ventricles, with symmetrical left and right ventricles. Early-FGR (compared with Late-FGR) had smaller hearts and globular left ventricles in unadjusted estimates, but after adjustment, sizes and shapes were similar.
Conclusion: FGR had significant impact on cardiac modelling, both unadjusted and when adjusted for gestational age, birth weight, sex and twin/singleton. The adjustments, however, refined the results notably and represents more specific the effects of FGR, thus underscoring the importance of adjustments in such studies.
Data-Driven Inference of Low Order Representations of Observable Dynamics for an Airfoil Model
Authors: Dewanjee Adharaa Neelim , Sahyoun Samir , Djouadi Seddik , Wilson Dan
Published: September 2022

We implement an adaptive isostable reduction strategy to obtain a data-driven reduced order model that captures the dynamics of observables in a computational model for fluid flow over an airfoil at moderate Reynolds numbers. The resulting model characterizes the response to both time-varying inflow conditions and Dirichlet boundary conditions on the surface of the airfoil meant to represent suction or blowing through the action of surface jets. The resulting reduced order model behaviors agree well with the dynamics of the full order model simulations in response to both open loop and closed loop inputs. This study provides a proof of concept that reduced order modeling techniques adaptive isostable coordinates can be successfully used in realistic fluid flow models using geometries with practical relevance.
Study of the Blume-Emery-Griffiths Model for Mixed Carbon-Like Nanotube: Monte Carlo Study
Authors: Fadil Z. , Saber N. , Eraki H. , Mhirech A. , Kabouchi B. , Bahmad L.
Published: September 2022

Monte Carlo study under the Metropolis algorithm is performed to investigate the ground phase diagrams and hysteresis electric cycles by using the Blume-Emery-Griffiths (BEG) model with the mixed spins (S-1, σ-3/2). Firstly, the ground state phase diagram has been established to show the more stable configurations corresponding to physical parameter EZ/JC. Moreover, the hysteresis electric cycle behaviors have been investigated by varying temperature, exchange coupling interactions, crystal field and biquadratic parameter of the carbon-like nanotube. It is found that the increase of the crystal field and the biquadratic exchange parameters decreases the surface of the loops leading to the apparition of the polarization plateaus.
Pretreatment platelet-to-lymphocyte ratio (PLR) as a prognosticating indicator for gastric cancer patients receiving immunotherapy
Authors: GOU Miaomiao , Zhang Yong
Published: September 2022

Background: Previous investigations suggest that systemic inflammation markers are able to provide prognostic value in several cancers. This study seeks to characterize the ability of pretreatment platelet-to-lymphocyte ratio (PLR) to prognosticate advanced or metastatic gastric cancer patients (AGC or MGC, respectively) receiving immunotherapy.
Method: AGC and MGC patients exposed to PD-1 inhibitors from January 2016 - August 2021 in the Chinese PLA General Hospital were recruited. Correlations between PLR and overall survival (OS), progression-free survival (PFS), and immunotherapy-associated tumor response rates were determined.
Results: 237 patients were enrolled for this retrospective investigation. The 6month and 12 month PFS based on the area under the curve value was 0.60 and 0.65 (p<0.05). based on a calculated PLR cut-off value of 139.41, The PLR <139.41 group has a longer OS in contrast with the PLR ≥139.41 group (13.46m vs 10.71m, HR = 0.57`, 95% CI, 0.42-0.78, p =0.004). The PLR <139.41 group had a PFS of 7.93m in contrast to the 4.75m seen in those with PLR ≥139.41 group (HR = 0.57`, 95% CI, 0.43-0.76, p=0.002). The disease control rate (DCR) and objective response rate (ORR) were 86.17% and 30.85%, respectively, in the PLR <139.41 group, but were 82.52% and 32.17%, respectively in the PLR ≥139.41 group. Both groups did not show any marked differences in terms of ORR and DCR (p=0.887, p=0.476). PLR is an independent prognostic indicator for OS and PFS upon uni- and multivariate analyses (p<0.05).
Conclusions: Pre-treatment PLR correlated significantly with PFS and OS in AGC and MGC patients who received immunotherapy. An elevated PLR may provide guidance on subsequent treatment options.
High performance piezoelectric MEMS loudspeaker based on an innovative wafer bonding process
Authors: Liechti Romain , Durand Stéphane , Hilt Thierry , Casset Fabrice , Dieppedale Christel , Colin Mikaël
Published: September 2022

Despite a significant number of new structures in the past few years, MEMS loudspeaker still aren't competitive in terms of performance compared to non-MEMS loudspeakers for free field applications. For industrial perspectives, a high sound pressure level on a wide frequency band is required, as well as a low total harmonic distortion. To widen the frequency range of MEMS loudspeakers, we propose to separate the actuating element from the radiating one, in order to separate design constraints to reach an optimal structure. In this paper, the lumped element model of the loudspeaker in presented, as well as the innovative manufacturing process. Finally, the computed frequency response is compared to the measured one. At the resonance, pressures as high as 110 dBSPL at 1 kHz and at 10 mm are reported, which is above the known state of the art for a loudspeaker with similar dimensions. Also, the flatness of the radiated sound pressure in a wide frequency range is closer to the ideal frequency response of loudspeakers than other MEMS loudspeakers, due to the piston mode of the moving rigid plate of the loudspeaker. The total harmonic distortion, mainly due to the nonlinearity of the piezoelectric transduction, is below 5% for reasonable sound pressure levels in the usable frequency band. The use of digital signal processing and of a dedicated packaging will allow our loudspeaker to advantageously replace the main or secondary one in smartphones.
Social network factors affect nutrition risk in middle-aged and older adults: results from the Canadian Longitudinal Study on Aging
Authors: Mills Christine Marie , Keller Heather H. , DePaul Vincent Gerard , Donnelly Catherine
Published: September 2022

Objectives: To determine which social network, demographic, and health-indicator variables are associated with SCREEN-8 (nutrition risk) scores at two time points, three years apart, using data from the Canadian Longitudinal Study on Aging.
Design: A retrospective cross-sectional study.
Setting and participants: 17051 Canadians aged 45 years and older with data from baseline and first follow-up of the Canadian Longitudinal Study on Aging.
Measurements: Nutrition risk was measured using SCREEN-8. Social network factors included social network size, frequency of contact with social network members, social participation, social support, self-rated social standing, and household income. Demographic variables included age, sex assigned at birth, marital status, educational attainment, and living situation (alone or with others). Health-indicator variables included depression, disability, and self-rated general health, mental health, healthy aging, and oral health. Multivariable linear regression was used to analyze the relationship between the social network, demographic, and health-indicator variables and SCREEN-8 scores at two time points, three years apart.
Results: Among the social network variables, social participation, self-rated social standing, and social support were predictors of SCREEN-8 scores at baseline and follow-up. Among the demographic variables, marital status was a predictor of SCREEN-8 scores at both time points. For the health-indicator variables, depression, self-rated general health, healthy aging, and oral health were predictors of SCREEN-8 scores at both time points. Age was a predictor of SCREEN-8 scores at baseline, but not at follow-up.
Conclusion: Individuals with low social participation, low social standing, and low social support may be at increased nutrition risk and should be proactively screened by healthcare professionals. Interventions and community programs designed to increase levels of social participation and foster social support may help to reduce the prevalence of nutrition risk.
Including Children with Autism Spectrum Disorder in mainstream Early Childhood Settings: What teachers do.
Authors: Higginson Raewyn
Published: September 2022

Autism Spectrum Disorder (ASD) is a label given to a neurological condition that causes people to act and think differently from neurotypical people. While there are New Zealand/Aotearoa studies reporting on children with ASD in more formal educational, compulsory settings, little is known about including children with ASD in mainstream early childhood settings. In this article the research focuses on investigating children with ASD who are included within three mainstream early childhood settings within one region of New Zealand/ Aotearoa, using case study methodology. The data collected included observations of teachers interacting with the child with ASD, semi-structured interviews with the key teacher, centre manager and the family/whānau of the child as well as collecting documents supporting the child within the centre. The findings indicate that all three ECE settings mostly included the child, while addressing some of their learning needs. However, it also highlighted the need for all teachers to have professional development when teaching children with ASD.
A Method of Identification of SARS-CoV-2 Variant Using NCBI BLAST-2 100% Homology Search with Specific Oligonucleotides Selected at the Deletion Boundaries of S, N, ORF7a, ORF8 and ORF1ab Proteins
Authors: CHAKRABORTY ASIT KUMAR
Published: September 2022

Genomic sequencing of many SARS-CoV-2 variants with higher transmission and immune-escape were reported due to point mutations and deletions. Thus, whether a newly sequenced SARS-CoV-2 belongs to Alpha, Beta, Gamma, Delta, or Omicron (BA.1, BA.2, BA.4 and BA.5) variants must be known. We multi-aligned the different Spike, ORF1ab and Nucleocapsid proteins of those corona virus variants and detected different lineage specific deletions and point mutations. Different COVID-19 sequences were aligned with CLUSTAL Omega software and oligonucleotides from deletion boundary were selected. BLAST search using those oligonucleotides clearly predicted the specific variant type with 100% homology and was very useful for new corona virus sequence characterization. Selection of sub-variants were done by oligonucleotides selected at the specific point mutation boundaries leading to amino acid change. COVID-19 variant status was not reported in most published corona virus sequences and this method would be very useful application to understand the nature of expected prognosis of corona virus infected patients in less technology-equipped countries.
Diagnostic, Prognostic, and Immunological Roles of CD177 in Cervical Cancer
Authors: Liao Wenxin , Li Wei , Li Yang , Liu Tingting , Wang Ying , Feng Dan , Shen Fujin
Published: September 2022

Background.
CD177, an indicator of prognosis in diverse cancers, is involved in the physiological processes of various tumor cells, and acts as an immune molecule with novel functions in cancer pathogenesis. However, the diagnostic, prognostic and immunological role of CD177 in cervical cancer remains unclear.
Methods.
Utilizing publicly available databases and integrating several bioinformatics analysis methods, we evaluated the expression level of CD177 in cervical cancer by GENT2, HPA and GEO databases. The Kaplan–Meier Plotter database, Xena Shiny and the constructed of a nomogram were clearly demonstrated its prognostic value for patients. Gene set enrichment analysis explored the relationship between CD177 and cervical cancer immune responses and immune cells infiltration level. In addition, we investigated the association between CD177 expression and stromalscore, immunescore, immune checkpoint and drug sensitivity by TCGA RNA-seq data.
Results.
CD177 was apparently expressed at low levels in cervical cancer and predicted a poor survival rate for patients. CD177 significantly activated immune-related signaling pathways and had a positive relationship with immune cell infiltration level. The high CD177 expression group possessed the high stromalscore and immunescore. CD177 had potential interactions with CTLA4, CD27, BLTA, CD200R1, CD80, NRP1, TNFRSF25, TIGIT, ICOS and TNFSF9 checkpoint markers. And CD177 expression was positively relevant with drug sensitivity for Lapatinib, Belinostat, ATRA, Gefitinib, Navitoclax and Tamoxifen.
Significance.
These findings may shed light on the vital role of CD177 in cervical cancer diagnosis, prognosis, and immunological function, and it may be a promising predictor and potential factor for cervical cancer patients.
Effect of Rapamycin Treatment in Human Seminoma TCam-2 Cells through Inhibition of G1-S Transition
Authors: Onel Tugce , Erdogan Cihan S. , Aru Basak , Yildirim Ecem , Demirel Gulderen Yanikkaya , Yaba Aylin
Published: September 2022

Introduction: Mammalian Target of Rapamycin (mTOR) is an important serine/threonine kinase that plays a critical role in several processes including cell cycle, protein synthesis and energy metabolism. Due to its multiple roles and general dysregulation in cancer, the mTOR pathway is an important target in cancer therapy. However, studies on mTOR activity in seminoma are limited. Therefore, our aim was to investigate the expression of mTOR signaling pathway proteins in the TCam-2 cell line after rapamycin treatment.
Methods: TCam-2 cells were treated with different concentrations of rapamycin (control (no rapamycin treatment), 4 nM, 20 nM, 100 nM, 500 nM and 1000 nM rapamycin) for 48 h and 72 h. mTOR, p-mTOR, P70S6K, p-P70S6K, proliferating cell nuclear antigen (PCNA) and Caspase-3 expression levels were analyzed by western blot. Apotosis and cell cycle were analyzed by flow cytometry.
Results: After 48 hours of rapamycin administration, mTOR activity was significantly decreased at 1000 nM (p<0.05). In addition, P70S6K acitivity significantly decreased in groups at all rapamycin concentrations (***p<0.001, ****p<0.0001). After 72 hours of rapamycin administration, mTOR pathway activity were significantly decreased at 100, 500 and 1000 nM rapamycin-treated groups (p<0.05). Moreover, P70S6K expression decreased in all treatment groups (****p<0.0001). Caspase-3 expression were similar in all groups. While PCNA expression tended to decrease at 48 h in a dose-dependent manner, this decrease was not significant. We detected decreased PCNA expression at 1000 nM rapamycin at 72 h (p<0.05). The rate of apoptosis increased especially at 1000 nM rapamycin at 72 hours (***p<0.001). On the other hand, according to the results of the cell cycle experiment, G1 phase arrest was detected at all rapamycin doses at 48 and 72 hours (***p<0.001).
Conclusion: our study indicated that 1000 nM rapamycin may inhibit TCam-2 seminoma cells growth by halting cell proliferation through inhibition of G1-S transition. Therefore we believe that the findings obtained will contribute to the development of new treatment approaches for seminoma patients in the future and in the process of restoring testicular functions and preserving fertility.
A new decision-marking model to improve the performance of technological innovation project
Authors: Chien Li-Chih , Liu Feng-Lang , Chang Ching-Ter
Published: September 2022

The promotion of technical and management capabilities is one of the important strategies in government policy to enhance the competitiveness of small and medium enterprises (SMEs). A serial of efficient and accurate decision-making models is then required to achieve this strategic goal. The construction machinery industry belongs to SMEs. It is also essential for infrastructure construction in Taiwan. This study aims to show the ways to improve the performance of SMEs in an uncertain environment. To deal with this issue, the Fuzzy Delphi method and fuzzy analytic hierarchy process (FAHP) are used to find key success factors (KSFs) of SMEs. TOPSIS method is used to find the best project leader for their projects. Also, the MCGP-U method is used to find the optimal resource allocations. In addition, the “plan-do-check-action cycle” is used to emphasize the importance of sustainable improvement. The contributions of the proposed model are as follows: (1) it considers multi-faceted of SMEs to avoid wrong decisions; (2) it can easily obtain the SEM’s KSFs to improve the performance of SMEs; and (3) the results of the study can be used to improve SEMs' managerial fitness and effectiveness.
Exploring the effect of job satisfaction, employee empowerment, and emotional intelligence on bank employee performance: A study on commercial banks in Bangladesh
Authors: M. Anwarul Islam K. , Mobarak Karim Md. , Islam Serajul , Shariful Haque Md. , Sultana Tania
Published: September 2022

Business organizations are facing ever-growing challenges in the competitive market regarding commitment, retention, engagement, and the belief of their employees. Employees are regarded as the lifeblood of every organization where the companies could not run their activities without skillful employees. The objective of this study is to explore the effect of job satisfaction, employee empowerment, and emotional intelligence on bank employees’ performance in the context of Bangladesh. In terms of the research purpose, non-probability convenience sampling has been used in this study. The targeted population was the commercial bank employees in Bangladesh. Regarding this study, total of 200 employees were asked to participate in this research. Among 200 employees, finally, 160 responses were received as complete with an 80% response rate. For analysis purposes, SPSS version 26.0 was used in this study. The study discovered that job satisfaction, employee empowerment, and emotional intelligence positively and significantly affect employee performance. The model explains 60 percent variance, and employee empowerment is found to have a higher impact on employee performance. Finally, this study will offer some extraordinary directions and implications for future research on commercial bank managers.
Outcome of Primary Management of Scleral Rupture without Vitrectomy Jakarta Eye Trauma Study
Authors: Simanjuntak Gilbert W.S , Raju Biju , Simanjuntak Golda A.M , Natali Reinne
Published: September 2022

Introduction:

To report the outcome of primary management of scleral rupture without vitrectomy.

Methods:

Descriptive retrospective study of primary surgical management of scleral rupture located anterior to the equator. Initial and final visual acuity (FVA, intra ocular pressure, type of injury (sharp/blunt/projectile), wound length, time interval between the incident and primary repair and cause of injury were recorded. Encircling scleral buckle was placed in case of scleral laceration reaching muscle insertion. Patients who had a follow up of 3 months after the primary repair were included in the study .

Results:

There were 41 patients out of 78 who had scleral rupture anterior to the equator. The average age was 21.27 + 9.73 years (range 3-50 years). Thirty-three (80.4%) were males and eight (19.6%) were females. Rupture was located superiorly) in 28 (68.3%) patients, and inferiorly in 13 (31.7%) patients. Eight patients underwent encircling buckle. The time interval from the injury till the primary repair less than 8 hours (p 0.000) and 8-24 hours (p 0.000) were associated significantly with FVA improvements. Initial VA correlated with FVA improvement significantly (p 0.001). Two patients with initial VA of LP became NLP, and they had a wound length 11 mm and 12 mm respectively.

Conclusion:

The primary management of scleral rupture anterior to the equator, without vitrectomy, improves VA significantly. Time interval less than 24 hours and shorter wound length correlated with significant improvement of final VA.
Logics of Re-Using Photographs: Negotiating the Mediality of the Magazine
Authors: Fröhlich Vincent , Morin Alice , Ruchatz Jens
Published: September 2022

This paper explores the logics of magazine re-uses through three case studies, by focusing on pictures produced and reproduced by way of photography. The first case study focuses on half-tone reproductions in the early phase of the development of news photography, using the example of Collier’s Weekly during the Russo-Japanese War. It offers a historical case of transfers between book and magazine. In our second case, examining the American and French editions of Vogue, internal re-uses of content demonstrate both collaborative networks as well as a certain amount of latitude for divergence, and therefore further distinction within the Condé Nast brand. Our last example analyses the re-use of film stills in popular illustrated film magazines. These magazines manage their dependency on existing visual material provided by distribution companies for free, while striving, simultaneously, to highlight their ‘profile’ through visual design. The specific ways in which each magazine re-used images shed light on how respective editorial identities are carved, as well as more generally on magazines’ mediality: the latter, we argue, is showcased, in highly competitive print markets, partly through distinct(ive) re-using practices.
Management of Students’ Report Cards for Improving Learning Quality in Selected Public Secondary Schools: A Case of Kisarawe District
Authors: Kamugisha Involatha , Osaki Kalafunja
Published: September 2022

The student report card is the main form of communication among teachers, students, and parents; and its purpose is to convey information from the school to parents about a students’ educational progress, usually at mid-year and the end of a school year. The study intended to assess the management of students’ report cards for improving learning quality in selected public secondary schools in Kisarawe District, Tanzania. The specific objectives were to; examine the role played by teachers in the management of SRCs towards students’ learning quality, evaluate parents’ perception on the management of SRCs in improving students’ learning quality and assess the usefulness of SRCs in influencing students’ learning. The study was guided by the Self-Efficacy Theory and the Social Constructivism Theory. The study employed a descriptive survey design. Respondents were drawn from four public secondary schools in Kisarawe District, and 132 respondents including parents, teachers, students, and heads of schools were involved. The study employed simple random sampling and purposive sampling to select respondents. Questionnaires, interviews, and documentary reviews were used as methods for data collection. Quantitative data obtained through questionnaire from teachers and students were analysed using the descriptive statistics technique. Qualitative data from interview of Heads of Schools and parents and documentary review of existing reports were analysed through the thematic analysis presented via narrations. The findings indicated that teachers were inactive in filling the assessment/progress results in SRC. Some of the reasons behind it being the large population of students in the classes, insufficient time for marking the tests, and recording of grades. Also, the study found that parents were unaware of their role in supporting their children to learn, they did not bother to attend the school meetings to collect their child’s report while others did not return feedback to the school management after receiving their children’s report cards. Recommendations are hereby made for the schools to establish a mechanism that will bring parents on board to participate in their children’s academic progress.
Actitudes y aptitudes que dieron origen al capitalismo
Authors: Alatorre Guzmán Diego
Published: September 2022

A través de un recorrido por las pequeñas modificaciones en el sistema de valores que tuvieron lugar al comienzo de la Ilustración, se hace una breve reseña del texto de Joel Mokyr “Attitudes, Aptitudes, and the Roots of the Great Enrichment”, y se propone una reflexión acerca de los efectos que el cambio actitudinal y aptitudinal significaron en términos ecológicos y sociales.
Tiburón azul: riesgo y beneficio de su consumo
Authors: Lara Ariagna , Perera-Valderrama Susana , Galván Magaña Felipe , Arreola Mendoza Laura , Marmolejo Rodríguez Ana Judith
Published: September 2022

El tiburón azul es uno de los más abundantes a nivel mundial y de los más capturados. Su carne tiene un alto valor nutritivo; sin embargo, al ser una especie de gran tamaño, de alto nivel trófico, longeva y altamente migratoria, es muy propensa a acumular elementos tóxicos en sus tejidos. Varios investigadores han encontrado en el músculo de organismos adultos de esta especie concentraciones de mercurio por encima del límite máximo permisible para el consumo humano (1.0 mg/Kg). En cambio, otros han reportado valores que no representan un riesgo para la población. No obstante que la concentración de mercurio esté por debajo del límite máximo establecido para un consumo seguro, en regiones costeras lo más acertado sería que el consumo sea limitado semanalmente, manteniéndose al mínimo, en particular en niños y mujeres embarazadas, que son los sectores de la población más vulnerables a los efectos de la bioacumulación de mercurio.
Twitter: un pretexto para investigar
Authors: Michán Aguirre Layla
Published: September 2022

La información especializada disponible en la web es diversa, inmensa y dinámica. En este contexto, las redes sociales se han constituido como una herramienta muy eficiente de comunicación. Twitter es una de las plataformas más utilizadas para generar, intercambiar y procesar información sobre biodiversidad por su versatilidad, por ser amigable, por su brevedad, inmediatez y eficiencia. Este ecosistema digital es abierto y reúne información de calidad generada por especialistas y entidades abiertos a la comunicación. En este texto explico brevemente su funcionamiento, comparto tips, formas de interactuar, expongo algunos ejemplos de cuentas, listas, etiquetas, y presento otras funciones para acceder a la información sobre biodiversidad en tiempo real, para recopilarla y guardarla. Todo esto convierte a Twitter en una aplicación idónea tanto para investigación como para la educación superior, porque contiene información rica, vasta y muy actualizada, ya que acerca a los alumnos, investigadores y maestros de manera entretenida e interactiva, y porque es una fuente infinita de datos, información y conocimiento, que permite vivir a los usuarios la experiencia de conversaciones sobre la ciencia real, además de participar, interactuar y ser leídos. ¡Nos vemos en Twitter!
Identification of Borassus Flabellifer Sap Compounds Against Angiotensin- Converting Enzyme for Potential Antihypertensive Inhibitors
Authors: Shobana M , Thilagavathi S
Published: September 2022

On a global scale, cardiovascular problems have become more important recently. The existing treatments for high blood pressure are generally unsuccessful and painful for patients. Since it poses a significant risk to the cardiovascular system and the general public's health, hypertension should be carefully managed. Hypertension with a systolic reading is extremely harmful. As a result, there is increased interest in creating antihypertensive drugs with natural ingredients. The study's key finding is that Borassus flabellifer sap comprises significant bioactive components, including 9,10-Anthracenedione. The angiotensin-converting enzyme (ACE), which converts angiotensin I into the active peptide vasoconstrictor hormone angiotensin II, may be inhibited by Borassus flabellifer, according to an in-silico investigation. The 9,10-Anthracenedione and ACE molecular docking investigation revealed extremely low binding energy (-8.6 kcal/mol). One must be aware of the ACE inhibitors that are already on the market to choose an efficient ACE inhibitor. Docking interactions of 9,10-Anthracenedione hence strongly imply its potential as an antihypertensive substance. It is a possible bioactive Borassus flabellifer sap ingredient for the creation of nutraceuticals and functional foods, as well as a candidate for the development of an efficient antihypertensive medicine. According to the study's findings, Borassus flabellifer sap is a potent nutraceutical compound that can be used to treat antihypertensive.
O gigante que acorda e vai às ruas: a produção simbólica, estética e insurgente das Jornadas de Junho
Authors: Santos Gustavo Souza
Published: September 2022

As Jornadas de Junho de 2013 no Brasil se desenvolveram como uma mobilização social em rede complexificada por dinâmicas socioespaciais, políticas e midiáticas. Ressalta-se ainda a produção de imagens, expressões e palavras de ordem que desenvolveram sentidos estéticos para a insurgência que ocupava as ruas, ativando territorialmente o país. Desse modo, propõe-se aqui concentrar o olhar sobre estes aspectos, refletindo a produção simbólica e estética insurgente nas Jornadas de Junho de 2013, considerando as palavras de ordem "vem pra rua" e "o gigante acordou". Inicialmente, discute-se a relação entre as práticas insurgentes e a produção estética com o suporte de Rancière. A seguir, analisa-se a produção simbólica de junho de 2013, evidenciando as duas expressões que aqui se propôs examinar. Por fim, debate-se as relações entre estética e ação coletiva na mobilização social. A variedade de pautas. a multiplicidade de atores e a multiescalaridade das territorialidades de insurgência produziram desenhos estéticos multivetoriais, catalisados pela performance corpográfica da mobilização híbrida, entre agências e potências on e off-line. Produziu-se uma partilha estética coadunada ao caráter multitudinário volátil do evento-fenômeno de junho de 2013.
Features of Medical Care Providing to Patients with Digestive Diseases in the Krasnodar Region during the COVID-19 Pandemic
Authors: Korochanskaya N. V. , Durleshter V. M. , Gabriel S. A. , Kovalevskaya O. V. , Serikova S. N. , Basenko M. A.
Published: September 2022

The aim of the study: optimization the medical care provision to patients with diseases of the digestive system (DD) in the Krasnodar Region during the COVID-19 pandemic.

Material and methods. The analysis of the features of the DD course in the Krasnodar Region was carried out according to the data of form C 51 “Distribution of the dead by sex, age groups and causes of death” of the Territorial Federal State Statistics Service in the Krasnodar Region, as well as monitoring the quality of medical care for patients with DD for the period from 2019 to 2021 years.

Results. During the COVID-19 pandemic, the routing of gastroenterological patients, dispensary observation and preventive measures have undergone some changes. In the structure of total mortality in the Krasnodar Region, mortality from DD was 21.6 % in 2020 and 4.0 % in 2021. The decrease in the growth of mortality rate, including from DD, in the second year of the pandemic is associated with the completed healthcare systems reformatting. The increase in hospital mortality in patients with gastric and duodenal ulcers, ulcerative colitis, and diverticular disease had a significant impact on mortality rates from DD. The decreasing number of hospitalizations was explained due to the conversion of a number of hospitals into hospitals for the treatment of patients with COVID-19. The hospitalization was mainly carried out for emergency indications and patients with a more severe course of the disease. The pandemic has increased the need for telemedicine: 378 tele-consultations on the gastroenterological profile was carried out in the Krasnodar Region in 2021.

Conclusion. Healthcare system workload in the Krasnodar Region increased significantly during the coronavirus pandemic that required a number of structural adjustments. In recent times, the regional health care is returning to the planned mode of providing medical care.
Desordens orais potencialmente malignas: uma análise bibliométrica dos trabalhos apresentados na Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
Authors: Oliveira Cruz Ana Karoliny , Marques Barbosa Geanderson José , Viana Gabriel Toscano , Costa Úrsula , Firmino Ramon Targino , Silva e Farias Ilky Pollansky , Goes Gonzaga Amanda Katarinny
Published: September 2022

Objetivo: as Desordens Orais Potencialmente Malignas (DOPMs) consistem em lesões e condições epiteliais que apresentam risco aumentado de malignidade. Nessa pesquisa, buscou-se identificar o perfil da produção científica brasileira sobre as DOPMs, a partir de uma análise bibliométrica dos trabalhos apresentados nas Reuniões da Sociedade Brasileira de Pesquisa Odontológica (SBPqO). Materiais e Métodos: foi realizado um estudo bibliométrico, em que foram analisados os anais das reuniões anuais da SBPqO realizadas entre 2015 a 2019. Incluiu-se resumos sobre DOPMs apresentados em qualquer categoria e as seguintes informações foram extraídas: ano, desenho do estudo, tipo de DOPM, unidade federativa, localização e instituição de ensino superior de origem. Os dados foram analisados por meio de estatística descritiva.  Resultados: foram identificados 91 resumos. A maior parte foi publicada em 2015 (24,2%) e por autores do estado de São Paulo (22%). A leucoplasia foi a desordem mais frequente (36,2%), seguida pela queilite actínica (35,2%). A maioria dos estudos foi de autoria de pesquisadores das regiões Sudeste (29%) e Sul (28%). Em relação à instituição de ensino, grande parte (68,1%) foi proveniente de universidades públicas. O tipo de estudo mais frequente foi pesquisa laboratorial básica (57,1%). Discussão: os achados do estudo indicam que o número de pesquisas sobre as DOPMs apresentadas nas Reuniões da SBPqO ainda é reduzido, concentrados na região sudeste e nas universidades públicas. Conclusão: realizar novas pesquisas a respeito desse tema é muito importante, pois permite a descoberta de informações relevantes para a saúde dos indivíduos frente a essa neoplasia.
Enseñanza de la investigacion de materiales dentales a nivel de pre y post-graduados [Título em português não disponível]
Authors: Mac-Pherson W. Guillermo
Published: September 2022

Vantagens decorrentes da participação de estudantes de odontologia em projetos de pesquisa. Considerações a respeito da atuação do Dentista na investigação científica, sua contribuição em relação à experiência profissional. Papel relevante do orientador; qualidades exigidas.
Cistos fissurais em embriões de rato e humano
Authors: Ebling Hardy
Published: September 2022

É demonstrada a importância do conhecimento dos cistos de desenvolvimento ou fissurais, para evitar confusão com cistos radiculares. Ressalta-se o conhecimento de embriologia, sem o que é impossível entender sua formação. Baseando-se em embriões humanos de rato, cão e gato, são apresentados casos de cisto mediano palatino e de formação cística do conduto de Wharton.