bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review of Fresh Osteochondral Allograft Transplantation for Osteochondral Lesions of the Talus
Authors: Pereira Gregory F. , Steele John , Fletcher Amanda N. , Adams Samuel B. , Clement Ryan B.
Published: November 2020

Category:

Ankle

Introduction/Purpose:

The term osteochondral lesion of the talus (OLT) refers to any pathology of the talar articular cartilage and corresponding subchondral bone. In general, OLTs can pose a formidable treatment challenge to the orthopaedic surgeon due to the poor intrinsic ability of cartilage to heal as well as the tenuous vascular supply to the talus. Although many treatment options exist, including microfracture, retrograde drilling, autologous chondrocyte implantation (ACI), and osteochondral autograft transfer system (OATS) these options may be inadequate to treat large cartilage lesions. Osteochondral allografts have demonstrated promise as the primary treatment for OLTs with substantial cartilage and bone involvement. To our knowledge, this is the first systematic review of outcomes after fresh osteochondral allograft transplantation for OLTs.

Methods:

PudMed, the Cochrane Central Register of Controlled Trials, EMBASE, and Medline were searched using PRISMA guidelines. Studies that evaluated outcomes in adult patients after fresh osteochondral allograft transplantation for chondral defects of the talus were included. Operative results, according to standardized scoring systems, such as the AOFAS Ankle/Hindfoot scale and the Visual Analog Scale were compared across various studies. The methodological quality of the included studies was assessed using the Coleman methodology score.

Results:

There were a total of 12 eligible studies reporting on 191 patients with OLTs with an average follow-up of 56.8 months (range 6-240). The mean age was 37.5 (range 17-74) years and the overall graft survival rate was 86.6%. The AOFAS Ankle/Hindfoot score was obtained pre- and postoperatively in 6 of the 12 studies and had significant improvements in each (P<0.05). Similarly, the VAS pain score was evaluated in 5 of the 12 studies and showed significant decreases (P<0.05) from pre- to postoperatively with an aggregate mean preoperative VAS score of 7.3 and an aggregate postoperative value of 2.6. The reported short-term complication rate was 0%. The overall failure rate was 13.4% and 21.6% percent of patients had subsequent procedures.

Conclusion:

The treatment of osteochondral lesions of the talus remains a challenge to orthopaedic surgeons. From this systematic review, one can conclude that osteochondral allograft transplantation for osteochondral lesions of the talus results in predictably favorable outcomes with an impressive graft survival rate and high satisfaction rates at intermediate follow-up. [Table: see text]
Primary Arthrodesis Versus Open Reduction and Internal Fixation Outcomes for Lisfranc Injuries: An Analysis of Conflicting Meta-analysis Results
Authors: Peters Wesley D. , Panchbhavi Vinod K.
Published: November 2020

Category:

Midfoot/Forefoot

Introduction/Purpose:

The superiority of Primary arthrodesis (PA) versus open reduction and internal fixation (ORIF) in Lisfranc injuries has been debated for decades. In recent years, researchers have attempted to use meta-analyses to reach a definitive conclusion. However, they have reached uncertain and contradicting conclusions when comparing these treatment options, which has led to more confusion. The goal of this paper is to navigate the primary source data of each meta-analyses to determine why different conclusions were reached and provide surgeons with more clarity on the comparable outcomes of PA and ORIF treatment options in Lisfranc injuries.

Methods:

A systematic literature review was conducted by searching for ‘meta-analysis’ AND ‘Lisfranc’ with keywords such as ‘ORIF’ OR ‘open reduction’ OR ‘Arthrodesis’ OR ‘fusion’. Five meta-analysis articles discussing PA and ORIF in Lisfranc injuries were identified. Study outcomes were extracted from each article for comparison. Contradicting conclusions were identified, and the primary sources used by each meta-analysis was analyzed.

Results:

All meta-analyses agreed that PA had lower rates of hardware removal and that there is no significant difference between PA and ORIF when considering revision surgery, anatomic reduction, postoperative infection, total complications, and patient satisfaction. However, contradicting conclusions were reached regarding functional patient outcomes such as return to duty, the American Orthopaedic Foot & Ankle Society (AOFAS) score, and visual analogue scale (VAS) score.

Conclusion:

PA has favorable rates of hardware removal compared to ORIF, while no difference between PA and ORIF was found for revision surgery, anatomic reduction, postoperative infection, total complications, and patient satisfaction.While certain meta-analyses had contradicting conclusion as to which treatment option is favorable for returning to duty, AOFAS score, and VAS score, it was determined there was no significant difference in PA and ORIF for return to work and VAS score. Repeat meta- analysis with truly equivocal outcomes would be necessary to reach a valid conclusion for return to full activity and AOFAS midfoot scores.
The Safety of Foot and Ankle Surgical Procedures at an Ambulatory Surgery Center
Authors: Peters Wesley D. , Adamson Peter J. , Janney Cory , Panchbhavi Vinod K.
Published: November 2020

Category:

Ankle; Bunion; Hindfoot; Lesser Toes; Midfoot/Forefoot

Introduction/Purpose:

There is a growing trend to perform surgical procedures at freestanding ambulatory surgical centers. No literature exists evaluating the rate of adverse events and overall safety of foot and ankle outpatient surgeries at a freestanding ambulatory surgery center (ASC).

Methods:

A retrospective review of all foot and ankle cases performed over a two year period at a single freestanding ASC. A total of 313 cases were performed. Adverse events are state-reported events that cause harm or lead to additional treatment. Using state-reported adverse events criteria and previous literature from hand and upper-extremity cases, we categorized our adverse events into seven categories: 1) infection requiring intravenous abx or return to the operating room, 2) postoperative transfer to a hospital, 3) wrong-site surgery, 4) retention of a foreign object, 5) postoperative symptomatic thromboembolism (DVT), 6) medication error, and 7) bleeding complications.

Results:

The overall rate of adverse events was 3.5% with 11 events identified over the two year period. There were a total of 10 infections and 1 symptomatic DVT. There were no cases that resulted in transfer to a hospital, hospital admission after discharge, medication error, bleeding complications, wrong-site procedures, or retained foreign bodies.

Conclusion:

Outpatient foot and ankle procedures are not without complications, but the overall rate of complications postoperatively is farly low (3.5%). Overall, foot and ankle surgeries can be performed safely in an outpatient setting at an ASC.
Factors Affecting the Outcomes of Tibiotalocalcaneal Fusion
Authors: Pitts Charles C. , Alexander Bradley , Washington Joshua L. , Barranco Hannah M. , Patel Romil K. , Cage Benjamin B. , Greco Elise M. , Shah Ashish
Published: November 2020

Category:

Hindfoot; Ankle; Ankle Arthritis

Introduction/Purpose:

Tibiotalocalcaneal (TTC) fusion is used to treat a variety of conditions affecting the ankle and subtalar joint, including osteoarthritis (OA), Charcot arthropathy, avascular necrosis (AVN) of the talus, failed total ankle arthroplasty, and severe deformity. The prevalence of postoperative complications remains high due to the complexity of hindfoot disease seen in these patients. The aim of this study was to analyze the relationship between preoperative conditions and postoperative complications in order to predict the outcome following primary TTC fusion.

Methods:

We retrospectively reviewed the medical records of 101 patients who underwent TTC fusion at the same institution between 2011 and 2019. Risk ratios (RRs) associated with age, sex, diabetes, cardiovascular disease, smoking, preoperative ankle deformity, and the use of bone graft during surgery were related to the postoperative complications. We determined from these data which pre- and perioperative factors significantly affected the outcome.

Results:

Patients with a preoperative diagnosis of Charcot arthropathy and non-traumatic OA had significantly higher nonunion rates of 44.4% (12 patients) and 39.1% (18 patients) (p = 0.016) and infection rates of 29.6% (eight patients) and 37% (17 patients) compared to patients with traumatic arthritis, respectively (p = 0.002). There was a significantly increased rate of nonunion in diabetic patients (RR 2.22; p = 0.010). Patients with chronic kidney disease were 2.37-times more likely to have a nonunion (p = 0.006). Patients aged over 60 years had more than a three-fold increase in the rate of postoperative infection (RR 3.60; p = 0.006). The use of bone graft appeared to be significantly protective against postoperative infection (p = 0.019).

Conclusion:

We were able to confirm, in the largest series of TTC ankle fusions currently in the literature, that there remains a high rate of complications following this procedure. Those with diabetes, chronic kidney disease, or aged over 60 years had an increased risk of nonunion. These findings help to confirm those of previous studies. Additionally, our study adds to the literature by showing that autologous bone graft may help in decreasing infection rates. This helps surgeons further understand which patients are at a higher risk for postoperative complications when undergoing TTC fusion. [Table: see text]
Preoperative and Postoperative PROMIS and FFI Scores Based on Region of Foot Pathology and Surgery
Authors: Pitts Charles C. , Alexander Bradley , Greco Elise M. , Cage Benjamin B. , Solar Spaulding F. , Sinha Tanvee , Shah Ashish
Published: November 2020

Category:

Other; Ankle; Ankle Arthritis; Bunion; Hindfoot; Lesser Toes; Midfoot/Forefoot

Introduction/Purpose:

The Patient-Reported Outcomes Measurement Instrumentation System (PROMIS) has become increasingly utilized in orthopaedic foot and ankle surgery to assess outcomes and better understand patient function, pain, and disability. Similarly, the Foot Function Index (FFI) is used to assess pain, disability, and activity limitation. PROMIS scores have been shown to predict, preoperatively, which patients will benefit most from foot and ankle surgery from a general perspective. It is currently unknown, with regard to chronic foot pathology, which region of the foot has the greatest effect on PROMIS and FFI scores and which region is affected the most by surgical intervention.

Methods:

PROMIS physical function, pain index, and depression scores along with FFI scoring subsets of pain, disability, and activity limitation were retrospectively reviewed for patients at a tertiary referral center with chronic pathology in either the hindfoot, midfoot, or forefoot that underwent surgery. Scores were obtained preoperatively and at 6 weeks postoperatively, and a preoperative to postoperative difference was calculated. Once the mean of each subcategory was obtained, an analysis of variance (ANOVA) was conducted in order to compare the means and identify statistically significant differences. Significance was set at p < 0.05 and p < 0.10.

Results:

There was no statistically significant difference between the mean preoperative PROMIS or FFI scores in the forefoot, midfoot, or hindfoot regions. There was also no statistically significant difference between means of PROMIS or FFI categories at 6 weeks postoperatively. However, the mean pre- to postoperative differences between PROMIS physical function scores of the forefoot, midfoot, and hindfoot were statistically significantly different at 9.12, 8.16, and 2.88, respectively (p=0.037). There was no statistically significant difference between the remaining scoring categories.

Conclusion:

Physical function, pain, depression, disability, and activity limitation are not affected disparately by the location of chronic pathology within the foot. Surgical intervention for problems in the forefoot, midfoot, and hindfoot does not provide differences in outcomes with regard to pain, disability, depression, or activity limitation based on region. Patients who have undergone surgical intervention for forefoot or midfoot pathology may experience greater improvements in physical function postoperatively when compared to patients who have undergone hindfoot surgery. [Table: see text]
Factors Affecting Emergency Department Visits, Readmissions, and Reoperations within 30 Days of Ankle Fracture Surgery: An Institutional Retrospective Study
Authors: Prather John C. , Alexander Bradley , Halstrom Jared R. , Sutherland Charles R. , Patel Akshar , McGwin Gerald , Shah Ashish
Published: November 2020

Category:

Ankle; Trauma

Introduction/Purpose:

With the U.S. healthcare system focused on value of care, providers and hospitals are increasingly measured by factors that increase patient care and decrease healthcare cost. Early postoperative adverse events not only increase healthcare cost, but also illuminate areas of potential improvement in patient care. This study aims to delineate factors that may influence emergency department visits, admissions, and reoperations within 30 days of ankle fracture surgery.

Methods:

This retrospective review of patients at a Level 1 trauma center evaluated 30-day outcomes after ankle fracture surgery over a 4-year period (2015-2018). The outcome measures assessed were emergency department visits within 30 days, unplanned readmissions within 30 days and unplanned return to the operating room (OR) within 30 days. Patient and injury characteristics were investigated as potential factors related to these 30-day outcomes. Multiple linear regression was used for outcomes. P-values less than 0.05 were considered significant.

Results:

A total of 619 patients were identified. After exclusion of concurrent pilon fractures, 596 patients were eligible for final analysis. Forty-three (7.2%) patients visited the emergency department within thirty days, 30 (5.0%) patients were readmitted within thirty days, and 10 (1.7%) patients requiring unplanned return to the OR within thirty days. Sex, insurance status, comorbidities such as pulmonary disease, diabetes mellitus, psychiatric disease, and chronic kidney disease, smoking status, and fracture type/location were not found to be significantly related to 30-day events. Age less than 45 was a significant risk factor for returning to the ED within 30 days (RR 2.1, p=0.02). Open fractures were more likely to require unplanned reoperation than closed fractures (RR 5.7, p<0.01).

Conclusion:

Age less than 45 years old was a risk factor for early ED visits. Open fractures were found to be at increased risk of needing unplanned reoperation. While further investigation into these risk factors is necessary to fully delineate a causal relationship, these findings can help physicians identify ‘at-risk’ populations after ankle fracture surgery and provide the necessary care to minimize early postoperative events. [Table: see text]
Complications Associated with Lisfranc Injury Open Reduction Internal Fixation versus Primary Arthrodesis: A Matched Cohort Study
Authors: Probasco William V. , Stein Benjamin E. , Fassihi Cyrus , Hossain Nazia
Published: November 2020

Category:

Trauma; Midfoot/Forefoot

Introduction/Purpose:

Lisfranc injuries are complex injuries of the midfoot in which the optimal course of treatment remains controversial. The objective of this study was to identify whether open reduction and internal fixation (ORIF) was associated with greater risk for surgical complications and/or greater financial burden in comparison to a primary arthrodesis (PA).

Methods:

A retrospective database review was conducted using the PearlDiver database to identify all Medicare patients who underwent a Lisfranc ORIF or PA in an inpatient setting from 2006-2013. Exclusion criteria included age >85 years and a prior history of foot or ankle trauma/infection/malignancy within 5 years of index surgery. Patients were matched in a 1:1 statistical manner to precisely control for potential influence of comorbidities and demographics, resulting in two cohorts with 2746 patients in each. Perioperative complications (within 30 days) were compared between the cohorts, in addition to the respective costs associated with each procedure. Complications were broken down into major (PE/DVT, MI, CVA, sepsis, mortality, nerve injury) or minor (UTI, PNA, hardware failure, transfusion, wound complications) categories.

Results:

No significant differences in major perioperative complications were noted between the two procedures. Significant differences were however noted in the incidence of minor perioperative complications, including higher rates of hardware failure (OR 0.26 (CI 95%, 0.07-0.752, P=0.021) and transfusion (OR 0.37 (CI 95%, 0.13-0.94, P=0.045) in the ORIF cohort. There was additionally a higher incidence of 30 day readmission (OR 0.35 (CI 95%, 0.24-0.51, P<0.001) with ORIF. Length of hospital stay (LOS) was shorter in the PA cohort (x̅; = 2.59 days) compared to the ORIF cohort (x̅; = 5.58 days, p < 0.001). Higher mean total hospital costs were noted for ORIF (x̅ = $66,342.56) compared to PA (x̅ = $40,761.65, p < 0.001).

Conclusion:

Within our study population, ORIF has a significantly higher rate of hardware failure and transfusion, and 2.5 times the risk of readmission within 30 days. When comparing the total cost of care, there was a significantly greater cost with ORIF. LOS was also significantly longer in the ORIF group. One weakness of this study was the ability to account for patients <65, as these were pooled into a single age group by the database. While revealing with regard to the aforementioned variables, further research still needs to be conducted on the functional outcomes of these procedures. [Table: see text][Table: see text][Table: see text]
Comparison of Topical Skin Adhesive and Simple Interrupted Nylon Sutures for Wound Closure in Forefoot Surgery: A Prospective Randomised Trial
Authors: Ray Robbie , Goff Thomas A. , Dearden Paul M. , Robinson Peter W. , Lam Peter , Wines Andrew P. , Lewis Thomas L.
Published: November 2020

Category:

Bunion

Introduction/Purpose:

There are many options for wound closure in forefoot surgery. The purpose of this study was to compare topical skin adhesive (2-Octyl-cyanoacrylate) to standard simple interrupted nylon sutures with attention to the quality of wound healing and the acceptability to the patient.

Methods:

Patients undergoing elective 1st ray forefoot surgery utilising a medial incision, either Hallux Valgus correction or 1st Metotarsophalangeal joint arthrodesis, were recruited to this study. Patients were randomly allocated during surgery to final layer wound closure with either the intervention topical skin adhesive (TSA) or the control interrupted nylon sutures (INS). Practicality was assessed by time taken for wound closure and subsequent time to perform wound care at 2 weeks postoperatively, wound care pain (VAS) and quality of wound healing was assessed at this point with a dedicated scoring tool, patient satisfaction and acceptability was assessed at 6 weeks postoperative.

Results:

70 patients (18 bilateral) were recruited, resulting 42 feet in each study group (after 4 exclusions for incomplete data set). Mean age 61 (29-83). There were no statistical differences in the demographics or surgery performed between groups. Wound closure time was significantly slower for TSA (272 secs (SD 72.2) vs 229 secs (SD 58.8), p=0.0038). At 2 weeks postoperative wound care time was significantly faster for TSA (71 secs (SD 50.8) vs 120 Secs (SD 47.8), p<0.0001), and patient reported pain was significantly less with TSA (VAS 0 vs 2, p=0.025). Significantly more inflammation and wound edge separation was recorded with TSA (17 vs 5 cases, p=0.006) and (12 vs 3 cases, p=0.02) respectively. High satisfaction was reported in both groups with no signifcant difference.

Conclusion:

Topical skin adhesive and interrupted nylon sutures are both acceptable closure methods for forefoot surgery with high satisfaction rates, low pain scores and low complications. However, the observation of significantly more inflammation and areas of wound separation at the early post-operative period with topical skin adhesive is sufficient to recommend routine use of sutures.
The Use of Single-Photon-Emission Computed Tomography (SPECT) for the Evaluation of Painful Ankle Arthroplasties
Authors: Refaie Ramsay , Shahid Zuhaib , Ramaskandhan Jayasree Ramas , Siddique Malik S.
Published: November 2020

Category:

Ankle; Ankle Arthritis

Introduction/Purpose:

The evaluation of the painful ankle arthroplasty remains challenging. Clinical and radiographic examination are the mainstay of surveillance. The use of CT is also widespread. In our series using CT we were however unable to reliably differentiate between prosthetic and other causes of pain. We do not therefore recommend the use of CT in evaluating this patient group. Since 2017 we have evaluated all cases of painful ankle replacement with single-photon-emission computed tomography (SPECT). The aim of this study was to review the use of SPECT in our patient cohort.

Methods:

A retrospective analysis of all ankle arthroplasties evaluated by SPECT was performed. Case notes, plain radiographic imaging and SPECT imaging were reviewed and tabulated for analysis.

Results:

29 painful ankle arthroplasties were identified and included in this study. Implants included 14 BOX, 11 Mobility, 3 Salto xt and 1 Zenith. The mean time from index surgery was 5 years (1 -11 years). Plain radiographs demonstrated no obvious abnormality in 18 out of 29 patients. Of these SPECT demonstrated abnormal periprosthetic uptake suggestive of loosening in 12 out of 18, in the remaining 6 no loosening / ankle pathology was identified. Of these 6 patients SPECT identified an area of extra- articular high uptake suggestive of a pain source in 3 cases (1 talonavicular joint, 1 subtalar joint and 1 syndesmosis). In the 11 patients with a demonstrable abnormality suggestive of loosening on plain imaging, SPECT confirmed the diagnosis in all 11 cases.

Conclusion:

SPECT is a useful tool in the evaluation of the painful ankle arthroplasty. SPECT provided confirmatory information where plain radiographs were positive but also helped elucidate potential causes of pain where plain radiographs were negative. We would no longer recommend the routine use of CT but rather would recommend the use of SPECT in the evaluation of all painful ankle arthroplasties.
Comparison Matrix-Associated Stem Cell Transplantation (MAST) with Autologous Matrix Induced Chondrogenesis plus Peripheral Blood Concentrate (AMIC+PBC) in Chondral Lesions at the Ankle - Matched-Patient Analysis
Authors: Richter Martinus , Zech Stefan , Meissner Stefan A. , Naef Issam
Published: November 2020

Category:

Ankle

Introduction/Purpose:

2016, the local government authorities re-categorized MAST, i.e. the included BMAC for impregnation of the matrix, as stem call manufacturing and heterologous transplantation. Consequently, MAST and all other procedures including BMAC were not ‘subject to disclosure’ as before but ‘subject to authorization’. Therefore, the authors´ institution was not authorized to perform MAST after July 16, 2016. The authors´ institution changed the treatment of chondral lesions by replacing BMAC as part of MAST to Peripheral Blood Concentrate (PBC) resulting in AMIC+PBC.The aim of the study was to compare MAST with AMIC+PBC in chondral lesions at the ankle.

Methods:

In a matched-patient clinical follow-up study, patients with chondral lesion at the ankle that were treated with AMIC+PBC from July 17, 2016 to May 31, 2017, and patients that were treated with MAST from April 1, 2009 to July 15, 2016 were included and compared. Size and location of the chondral lesions and the Visual-Analogue-Scale Foot and Ankle (VAS FA) before treatment and at follow-up were analysed. Bone Marrow Aspirate Concentrate (BMAC) was used for MAST and Peripheral Blood Concentrate (PBC) for AMIC+PBC to impregnate a collagen I/III matrix (Chondro-Gide, Wollhusen, Switzerland) that was fixed into the chondral lesion with fibrin glue.

Results:

One hundred and twenty-nine patients with 136 chondral lesions were included in both groups. The chondral lesions were located as follows (MAST/AMIC+PBC, n (%)), medial talar shoulder only, 59 (43)/62 (46); lateral talar shoulder only, 44 (32)/42 (31); medial and lateral talar shoulder, 7 (10)/7 (10); tibia, 19 (14)/18 (13). The lesion size was 1.6/1.8cm2 on average and VAS FA was 46.9/45.7 (MAST/AMIC+PBC). For MAST/AMIC+PBC groups, 107 (83%)/105 (81%) with 112/110 previous chondral lesions completed the defined 2-year-follow-up after 24.4/23.8 months on average. VAS FA improved to 82.3/79.8 (MAST/AMIC+PBC). No parameter significantly differed between MAST and AMIC+PBC groups.

Conclusion:

MAST and AMIC+PBC as part of a complex surgical approach led to improved and high validated outcome scores in 2-year-follow-up. MAST and AMIC+PBC showed similar results. No method related complications were registered.
Comparison of Clinically used Bilayer Collagen Membrane and Trilayer Collagen Prototype Fixation Stability in Chondral Defects at the Talus: An Experimental Human Specimen Study
Authors: Richter Martinus , Milstrey Alexander , Zech Stefan , Grueter Angelika , Evers Julia , Raschke Michael J. , Ochman Sabine
Published: November 2020

Category:

Basic Sciences/Biologics

Introduction/Purpose:

The purpose of this human specimen experimental study was to compare the fixation stability of clinically used bilayer collagen membrane with fibrin glue (Chondro-Gide, Geistlich Pharma AG, Wollhusen, Switzerland) with trilayer collagen prototype without fibrin glue in chondral defects at the medial or lateral talar shoulder.

Methods:

Eleven human specimens were used. The membranes were implanted in standardized chondral defects at the medial and lateral talar shoulder (randomized). All tests were performed in load-control (15kg). Range of motion (ROM) of each ankle was examined individually before testing. The average ROM was 10° dorsalextension (range 0°-20°) and 30° plantarflexion (range 20°-45°). 1,000 testing cycles with the defined ROM were performed. Two independent investigators, blinded to fixation and membrane type, visually assessed the membrane fixation integrity for peripheral detachment, area of defect uncovered, membrane constitution and delamination.

Results:

The clinically used bilayer collagen membrane plus fibrin glue showed higher fixation stability than the trilayer prototype (all p<0.05). No significant differences occurred between medial and lateral talar shoulder location (all p>0.05).

Conclusion:

The fixation stability of the trilayer collagen prototype without fibrin glue is lower than of the clinically used bilayer membrane with fibrin glue in chondral defects at the medial and lateral talar shoulder in an experimental human specimen test. Clinical use of trilayer collagen prototype without fibrin glue has to be validated by clinical testing to evaluate if the lower stability of fixation is still sufficient.
Semi-automatic Software-based 3D-Angular Measurement For Weight-Bearing CT (WBCT) is 97% Faster than Measurement by Hand and Provides Similar Angles
Authors: Richter Martinus , Zech Stefan , Meissner Stefan A. , Naef Issam
Published: November 2020

Category:

Basic Sciences/Biologics

Introduction/Purpose:

Weight-bearing CT (WBCT) has been proven to allow for more precise and valid measurement of bone position (angles) than conventional weight-bearing radiographs (R) and conventional CT without weight-bearing (CT)1. The measurement by hand (MBH) has demonstrated adequate inter- and intraobserver reliability but high time consumption1. Recently, a semi-automatic software-based angular measurement (SAM) has been developed (Disior Ltd, Helsinki, Finland). The purpose of this study was to compare SAM with MBH regarding angles values and time spent for the investigator.

Methods:

Fifteen bilateral WBCT scans (PedCAT, Curvebeam, Warrington, PA, USA) were randomly extracted from a local institutional database with more than 13,000 scans. Nineteen angles as shown in table 1 were measured with MBH as previously described and with SAM1. SAM includes software generated 3D models with semi-automatic bone specification of tibia, fibula, talus, calcaneus, navicular, cuboid, cuneiforms and metatarsals. The software automatically defines the longitudinal axes of these bones and automatically measures the angles between these axes. The time spent of the investigator for the measurements was recorded (total process MBH and specification of bones for SAM). The software calculation time for SAM was not measured or considered as investigator time spent. The angles and time spent of MBH and SAM were compared (t-test, homoscedatic).

Results:

Mean age of the subject was 58 years (range, 7-81), 12 (40%) were male. The pathologies were bilateral in 8 (54%), right in 4 (27%) and left in 3 (20%) subjects (23 feet in total) and were specified as follows, ankle osteoarthritis/instability in 6 (26%), Haglund deformity/Achillodynia in 4 (17%), Forefoot deformity in 7 (30%), Charcot arthropathy in 2 (9%), flatfoot in 4 (17%) feet. The angles did not differ between MBH and SAM (Table 1, each p>.05). The time spent for MBH / SAM was 780+-171s / 20+-8 s on average in total for 19 angles and 41+-9s / 1+-0.4 s per angle (p<.01).

Conclusion:

This is the first study comparing MBH with SAM. SAM shows similar angles as MBH and can be also considered as reliable measurement option. The investigator time spent is 97% lower for SAM (1 s per angle) than for MBH (41 s per angle). SAM is an important step forward for 3D-angle measurement of WBCT. The next desired is fully automatic software-based measurement. References1. Richter M, Seidl B, Zech S, Hahn S. PedCAT for 3D-Imaging in Standing Position Allows for More Accurate Bone Position (Angle) Measurement than Radiographs or CT. Foot Ankle Surg 2014;20:201-7. [Table: see text]
Instagram and Pilon Fractures: An Analysis of Social Media and its Relationship to Patient Injury Perception
Authors: Rizkalla James M. , Lines Tanner , Daoud Yahya , Zide Jacob R.
Published: November 2020

Category:

Ankle; Ankle Arthritis; Trauma

Introduction/Purpose:

Patients have begun to utilize social media networking sites to discuss their individual experiences with medical care. Social media as an adjunct tool to measure patient satisfaction, progress, and long-term rehabilitation after orthopaedic procedures may hold future promise. The purpose of this study was to investigate social media posts regarding pilon fractures and their relationship to patient injury perception.

Methods:

We evaluated Instagram media posts in patients who have suffered pilon fractures for the following variables: gender, tone, discussion of rehabilitation, activities of daily living (ADL) reference, incision/scar reference, pain, post of radiograph/imaging, external fixation reference, discussion of bracing/splinting, pre or post-operative swelling, and need for reoperation. In total, 241 patient posts were included for investigation and analysis of patient injury perception via social media.

Results:

Of all included posts, 88% of posts had a positive tone. A majority of the posts (66.8%) mentioned rehabilitation and post-operative progress. There were significant associations between positive tone and rehabilitation (p=0.0001), as well as positive tone and Activities of Daily Living (ADLs) (p=0.0361).

Conclusion:

Outcomes after surgical management of pilon fractures are generally poor. Nonetheless, this analysis of patients sharing their experience on social media after ORIF of pilon fractures demonstrates a mostly positive attitude toward the injury and recovery. A positive tone of the post was significantly associated with mentions of rehabilitation and ADLs.
A Retrospective Chart Review to Examine Failed Modified Brostrom Procedures for Chronic Lateral Ankle Instability
Authors: Rizzo Kaitlyn , Brandle Greggory , Cheney Nicholas A. , Clark Brian C.
Published: November 2020

Category:

Ankle; Other

Introduction/Purpose:

Recurrent ankle injuries can lead to chronic ankle instability requiring surgical stabilization. Since the anterior talofibular ligament (ATFL) is the weakest of the lateral ankle ligaments, repair is often required in cases of chronic lateral ankle instability. Damage to the calcaneofibular ligament (CFL) is less common than the ATFL, but additional repair of it in these cases may be necessary to avoid this recurrent instability. A modified Brostrom procedure has been a widely accepted surgical approach to chronic lateral ankle instability if conservative measures fail. However, cases of recurrent instability even after initial stabilization surgery can present. The purpose was to examine reasoning for and rate of revision surgeries attempting to fix chronic lateral ankle instability as it relates to the ATFL and CFL integrity.

Methods:

A retrospective chart review was conducted to assess outcomes of a modified Brostrom procedure to determine underlying reasoning of the need for revision surgery by utilizing results of the anterior drawer and varus tilt tests. The files of these patients were examined via electronic health records to determine the reasoning for surgery. The preoperative and postoperative results of the anterior drawer test (ADT) and varus tilt test were used to examine ATFL and CFL integrity, respectively, in addition to operative notes.

Results:

172 patients met criteria having undergone a modified Brostrom dual ligament repair procedure for lateral ankle instability by a single orthopedic foot and ankle surgeon. With a 3.49% revision rate in the patient population, the only similarity found in all of the patients was the presence of a positive varus tilt test indicating the CFL was a major contributor of failed correction via the modified Brostrom procedure. One patient had a positive ADT, and one had a mildly positive ADT. These ADT and varus tests were performed at various time points in the care of the patients. The average length between surgeries was calculated to be 624.2 days. This revision rate is higher than past studies but was limited to a few years under examination.

Conclusion:

In conclusion, the anterior drawer and varus tilt tests are utilized to determine the integrity of the ATFL and CFL in the lateral ankle ligament complex. In failed modified Brostrom procedures examined, the positive result was consistently in the varus tilt test, indicating that the CFL is the ligament most affected in these patients requiring additional surgery. However, these physical exam tests are only one way to examine the ankle and do not take additional pathologies of the lateral ankle into account. Additional studies are needed to examine long-term outcomes of the modified Brostrom procedure and reasoning for failure.
Percutaneous Chevron Akin (PECA) Correction of Hallux Valgus Deformity: Analysis of the Learning Curve
Authors: Robinson Peter W. , Ray Robbie , Dearden Paul M. , Goff Thomas A. , Whitehouse Michael R. , Lam Peter , Dracopoulos George
Published: November 2020

Category:

Bunion

Introduction/Purpose:

Percutaneous hallux valgus correction is increasing in popularity, with good correction of deformity and improvement in outcomes. The learning curve is reported as steep, based on arbitrary analysis.

Methods:

We performed a prospective study of a single surgeon series on the 1st 58 feet in 53 patients undergoing PECA hallux valgus correction, following cadaveric training and surgical observation. Pre- & post-operative (6 month) hallux valgus angles (HVA) & 1-2 intermetatarsal angles (IMA) were measured on weight bearing radiographs. Tourniquet time & number of fluoroscopy images were recorded. Complications were analysed. Parametric data was described with mean+-SD & non- parametric data with median+-interquartile range. Unpaired 2-tailed t tests were used to compare continuous data. The learning curve was calculated by plotting the tourniquet time against case number using a smoothed cubic spline with straight lines fitted to the slope. This was used to define a learning phase & a plateau phase.

Results:

Median age was 62 (IQR 56-66). The mean HVA improved from 32°+-4.7 to 9°--+-5.9 (p<0.0001). Mean IMA improved from 16°+-3.1 to 8°+-2.3 (p<0.0001). There were 6 re-operations (ostectomy & screw removal). The learning curve inflection point was between case 38 & 39. 38 were analysed in the learning phase & the remaining 20 in the plateau phase. No significant difference between the learning and plateau phases were seen for age, pre- & post-operative HMA or IMA, difference from normal angles or return to theatre. Pearson correlation revealed that only tourniquet time (p=0.001) & number of fluoroscopy shots (p=0.019) were significantly correlated with the learning or plateau phase.

Conclusion:

The learning curve for the PECA hallux valgus technique is around 40 cases, reflected by tourniquet time and number of fluoroscopy shots. It does not affect radiological correction or complications, showing that if taught properly this technique is reproducible and reliable.
Management of Ankle Fractures with Syndesmotic Disruption: A Survey of Orthopaedic Surgeons
Authors: Rogero Ryan G. , Illical Emmanuel M. , Corr Daniel , Raikin Steven M. , Krieg James , Tsai Justin
Published: November 2020

Category:

Ankle; Trauma

Introduction/Purpose:

With an increasing frequency of syndesmotic fixation during ankle fracture ORIF and no current gold standard management protocol, it is important for surgeons to understand the frequency and usage patterns of the various techniques among other orthopaedic surgeons. The purposes of this study are to determine how orthopaedic surgeons currently manage ankle fractures with concomitant syndesmotic disruption and to identify surgeon demographics predictive of syndesmotic management.

Methods:

An 18-question survey, including 10 specific syndesmotic management questions was sent to the Orthopaedic Trauma Association (OTA) and Canadian Orthopaedic Association (COA), as well as sent to email addresses of foot and ankle-fellowship trained surgeons. Surgeon demographic questions included years, country, and type of practice, fellowship(s) completed, setting of ankle fracture surgery, and number of ankle fractures operated on per year. Multinomial regression analysis was performed to determine if surgeon demographics were predictive of syndesmotic management.

Results:

One-hundred ten orthopaedic surgeons completed our survey. Selected predictors of syndesmotic management included: private practice with academic appointments (0.077 [0.007, 0.834]; p=0.035) being predictive of not using screws through an ORIF plate; foot & ankle fellowship (9.981 [1.787, 55.764]; p=0.009) and trauma fellowship (6.644 [1.302, 33.916]; p=0.023) predictive of utilizing screws through a plate; no fellowship (14.886 [1.226, 180.695]; p=0.034) predictive of only using 1 screw; and surgeons practicing in the U.S. were more likely to not use screws across just 3 cortices (0.031 [0.810, 3.660]; p=0.009). Additionally, among those utilizing suture-button devices, foot & ankle fellowship-trained surgeons were more likely to implement suture-button through plate (7.676 [1.286, 45.806]; p=0.025).

Conclusion:

Several surgeon factors influence decision making in the management of ankle fractures with syndesmotic disruption. This study raises awareness of differences in management strategies that should be used for further discussion when determining a potential gold standard for management of these complex injuries.
Early Outcomes with the CADENCE Total Ankle Prosthesis
Authors: Rushing Calvin J. , Berlet Gregory C. , Hyer Christopher F.
Published: November 2020

Category:

Ankle Arthritis; Ankle; Other

Introduction/Purpose:

A number of two-component, 4th generation total ankle arthroplasty (TAA) prostheses have been introduced to the market within the past few years. The purpose of the present study was to assess early outcomes for the CADENCE total ankle prosthesis.

Methods:

All patients who underwent primary TAA with CADENCE between August 2016 and June 2018 at a single institution and who were at least 1 year postoperative were included. A total of 32 ankles with a mean follow up of 19 (range, 12-33) months met the criteria. Weightbearing radiographs were assessed using coronal and sagittal alignment parameters preoperatively, at 6 weeks postoperative, and at the most recent follow-up. Medical records and charts were reviewed and revisions, reoperations, and complications were classified according to the criteria established by Vander Griend et al. and Glazebrook at el., respectively.

Results:

Survivorship for the CADENCE prosthesis was 93.7%. Coronal and sagittal tibiotalar alignment significantly improved after surgery (p< 0.001, p< 0.005), and was maintained at the latest follow-up (p=0.44, p=0.30). Overall, two ankles (6.3%) underwent early revision for aseptic loosening; while 6 (18.8%) underwent a non-revisional reoperation. Nine ankles (28.1%) presented a total of 13 complications (4 high grade, 2 intermediate, and 7 low) according to the Glazebrook classification system. The most common was intraoperative periprosthetic medial malleolar fracture (5 ankles, 15.6%), a low-grade complication.

Conclusion:

Satisfactory outcomes were observed at short-term follow-up for the CADENCE prosthesis. Additional studies with longer follow-up are warranted.
Risk Factors for Early Failure of 4th Generation Total Ankle Arthroplasty Prostheses
Authors: Rushing Calvin J. , Hyer Christopher F. , Berlet Gregory C.
Published: November 2020

Category:

Ankle Arthritis; Ankle; Other

Introduction/Purpose:

A number of two-component, 4th generation total ankle arthroplasty (TAA) prostheses have been introduced to the market in the past few years, as the popularity and indications for TAA have continued to expand. The purpose of the present study was to identify independent risk factors for the early failure of 4th generation TAA prostheses.

Methods:

A total of 97 ankles underwent TAA with a 4th generation prostheses (INFINITY, CADENCE) between August 2015 and June 2018 at a single institution and were at least 6 months postoperative (mean 18.3 months, range 6-43). The primary outcome assessed was the need for revision surgery, defined as removal of 1 or both metal components for any reason, excluding infection. Baseline patient demographics, characteristics, radiographic alignment parameters, and distal tibia cortical bone thickness (CBT) were assessed. Revisions, reoperations, and complications were classified according to the criteria established by Vander Griend et al. and Glazebrook et el., respectively. Univariate and multivariate analyses were performed.

Results:

Three ankles (3.1%) underwent revision surgery for aseptic loosening at a mean of 24.3 (range, 16-31) months; all had a CBT <4mm. Independent predictors for reoperation were a CBT < 4mm, the presence of diabetes, and ipsilateral hindfoot fusion (p=0.04). No associations were identified for purported risk factors (age, BMI, and coronal deformity).

Conclusion:

The present study is the first to suggest a potential relationship between CBT of the distal tibia and TAA failure. Additional studies are warranted to better understand the role of bone density in TAA survivorship.
Shortening of the First Ray After First Tarsometatarsal Joint Fusion: A Cadaveric Comparison Between Curettage Versus Planal Resection
Authors: Rushing Calvin J. , McKenna Bryon J. , Langan Travis M. , Bull Patrick E. , Hyer Christopher F. , Berlet Gregory C.
Published: November 2020

Category:

Bunion; Midfoot/Forefoot; Other

Introduction/Purpose:

Potential shortening of the first ray is an important consideration when performing a first tarsometatarsal (TMTJ) fusion. However, no previous study has sought to directly quantify the resultant shortening after TMTJ fusion. The purpose of the present anatomic study was to directly assess and compare shortening of the first ray using two joint preparation techniques (curettage, planal resection) for first TMTJ fusion.

Methods:

Ten pairs of matched lower extremity cadaver specimens were divided into two groups. Preoperative length assessments were performed at the first TMTJ dorsally and plantarly using a digital caliper. In Group 1, joint preparation for first TMTJ fusion was performed with curettage, whereas specimens in Group 2 underwent planal resection. Post-operative length assessments were repeated. All data was analyzed using two-tailed Students t-tests.

Results:

Mean shortening of the first ray following curettage was 1.1 (range, 0.3 to 2.0) mm dorsally and 1.6 (range, 0.6 to 3.7) mm plantarly; while mean shortening following planal resection was 4.5 (range, 2.7 to 7.9) mm dorsally and 4.6 (range, 2.4 to 8.9) mm plantarly. The measured differences were statistically significant (p <0.001, p=0.001).

Conclusion:

Both curettage and planal resection resulted in shortening of the first ray after first TMTJ fusion. Planal resection resulted in significantly more shortening, which was also more variable. Surgeons performing first TMTJ fusions may consider curettage over planal resection to mitigate the risk of painful postoperative transfer metatarsalgia.
The INFINITY Total Ankle Prosthesis: Outcomes at Short Term Follow-up
Authors: Rushing Calvin J. , Hyer Christopher F. , Berlet Gregory C.
Published: November 2020

Category:

Ankle Arthritis; Ankle; Other

Introduction/Purpose:

The INFINITY total ankle prosthesis remains the most widely used 4th generation total ankle arthroplasty (TAA) system in the United States. The purpose of the present study was to assess outcomes for the INFINITY prosthesis at short-term follow-up.

Methods:

All patients who underwent primary TAA with INFINITY between August 2015 and June 2018 at a single institution and who were at least 1 year postoperative were included. A total of 55 ankles with a mean follow up 22 (range, 12-43) months met the criteria. Weightbearing radiographs were assessed using coronal and sagittal alignment parameters preoperatively, at 6- 8 weeks postoperatively, and at the most recent follow-up. Medical records and charts were reviewed and revisions, reoperations, and complications were classified according to the criteria established by Vander Griend et al. and Glazebrook at el., respectively.

Results:

Overall survivorship for the INFINITY prosthesis was 98.2%. Coronal and sagittal tibiotalar alignment improved after surgery (p<.001, p=0.09), and was maintained during the latest follow-up (p=0.62, p=0.47). One ankle (1.8%) required early component revision; while 5 (9.1%) required non-implant related revision. Postoperative periprosthetic lucency’s were observed in nineteen ankles (34.5%); most of which were non-progressive (17 ankles, 89.5%). Thirteen complications (3 high grade, 3 intermediate, and 7 low) in 11 ankles (20%) were recorded according to the Glazebrook classification system.

Conclusion:

INFINITY survivorship was 98.2% at a mean of 1.8 years of follow-up, with only 1 ankle requiring prosthetic revision. Additional studies with longer follow-up are warranted for 4th generation TAA prostheses.