bluuebunny/crossref_metadata_2025 huggingface dataset:
DNA Methylation in Aortic Aneurysms of Different Localization
Authors: Kucher A. N. , Shipulina S. A. , Goncharova I. A. , Nazarenko M. S.
Published: October 2024

Aortic aneurysm (AA) is a life-threatening condition, and aortic rupture that is the complication of AA in the absence of emergency surgery leads to death. Genetic (more often in thoracic AA – TAA) and environmental factors (in TAA and abdominal AA – AAA) contribute to the development of AA. This review summarizes the data of scientific publications devoted to the study of DNA methylation under the influence of AA risk factors, as well as in the cells of different parts of the aorta (thoracic, abdominal) in normal and pathological conditions. Changes in DNA methylation are observed in aortic and/or blood cells in the presence of AA risk factors (arterial hypertension, smoking, age, presence of comorbidities). Studies of DNA methylation in TAA and AAA are few and have been conducted using different approaches to sample formation, cell sample selection, and experimental methods. However, they provide convincing evidence of the altered DNA methylation status of genes selected for study using a candidate approach (in the AAA study), as well as of different genomic regions in genome-wide DNA methylation analysis (mainly in TAA studies). Genes localized in differentially methylated regions are associated with the functioning of the cardiovascular system and are involved in cellular and metabolic processes pathogenetically significant for the development of AA. In a number of cases, the association of DNA methylation levels with clinical parameters in AA has been established. These results indicate the prospect of expanding the studies of DNA methylation in AA, including the identification of new pathogenetically significant links in AA development.
Foreign migrants in the Moscow agglomeration: spatial and temporal analysis based on data from mobile operators
Authors: Babkin R. А. , Makhrova A. G. , Medvednikova D. M.
Published: October 2024

The article analyzes the modern ethnic landscape of the Moscow agglomeration on the basis of data from mobile operators. The estimation of the number of foreign migrants and its monthly dynamics from October 2021 to October 2022 is made. The main areas of residence of foreigners have been identified, the ethnic diversity of municipalities has been assessed, and the main types of settlement pattern of national-ethnic communities have been identified. The study showed that the total number of foreign migrants in the agglomeration reaches 1.8 million people or 9% of the total population, remaining almost unchanged in spite of events of 2022, including the special military operation. The share of foreigners is minimal in ZATO (below 3%), it is also insignificant in the far suburbs of Moscow and in expensive districts of the capital city. At the same time, the threshold of 17% (the so-called “boiling point”, reflecting a sharp increase in the risks of interethnic conflicts and ghettoization of urban space) was overcome by 8 municipalities in the agglomeration. The two most noticeable areas of increased concentration of foreign migrants are identified in the south-east at the junction of Moscow and Moscow region (Lublino – Kotelniki) and in New Moscow (Mosrentgen – Sosenskoye). The calculation of the Ekkel ethnic mosaic index confirmed the presence of pronounced interethnic contact zones here. Increased index values were also noted in most central and southwest districts of Moscow, which, with a smaller proportion of foreigners living, are associated with a high density of offices, diplomatic institutions and universities. Three types of settlement patterns of national-ethnic groups of migrants, determined by the adaptive capabilities of ethnic communities, were revealed. Diffuse and relatively uniform settlement pattern is characteristic for both the most massive ethnic groups (citizens of Tajikistan, Uzbekistan and Kyrgyzstan) and the most culturally close to the local population (citizens of Ukraine and Belarus). Concentric settlement pattern (in residential areas of Moscow and satellite cities) is typical for relatively large ethnic groups coming from post-Soviet countries (citizens of Azerbaijan, Armenia, Georgia). The local settlement pattern is typical for small ethnic communities that gravitate to specific districts of the capital city.
Mengenal Konsep Deret Aritmatika Dan Geometri Dengan Benar Di SD S Al-Ittihadiyah
Authors: Sitorus Putri Aulia , Bone Nur Rahma , Wandini Rora Rizki
Published: October 2024

Matematika adalah pelajaran yang paling dasar yang digunakan untuk mempelajari pelajaran-pelajaran lain. Misalnya pelajaran ekonomi, akuntansi, manajemen, atau pelajaran IPA seperti: biologi, kimia, atau fisika. Semua pelajaran ini kan pasti akan berhitung, membagi, mengkali, serta mengurangi, jadi jika tidak mempelajari pelajaran matematika bagaimana semua pelajaran tersebut bisa diketahui tanpa mengetahui terlebih dahulu. Tujuan penelitian ini ialah untuk mengetahui bagaimana siswa di SD S AL-Ittihadiyah mengenal atau mengetahui konsep deret aritmatika dan geometri. Metode yang digunakan dalam penelitian ini ialah metode kualitatif dengan wawancara dan pengamatan, subjek penelitian ini ialah siswa-siswi kelas VI di SD laut dendang. Hasil penelitian ini menunjukkan bahwa hanya beberapa siswa yang kurang paham tentang deret aritmatika dan geometri.
Archaeology of Ruderal Futurism
Authors: Young Alex
Published: October 2024

Language used to describe plant life and their environments is shaped by how plants are perceived. In turn this language reproduces how plants continue to be perceived and contributes to the further shaping of attitudes toward them. This essay presents the ruderal as a framework for understanding and envisioning being-with more-than-human others in a world altered by colonial and capitalist exploitation, extraction and expansion. Enacting an archaeological tracing of language and cultural thought towards ruderal plant species, consideration is given to: vernacular language applied to vegetal beings; identities of belonging applied to the movement of vegetation at a planetary scale; and decolonial modes of thinking-with and being-with vegetal others in the aftermath of colonialism and capitalism. Particular consideration here is given to the classification systems of botanist Albert Thellung, the thought of gardener and landscape architect Gilles Clément and the work of artist Andrea Callar. This paper extends an ongoing area of research I have previously examined in the curatorial research project Ruderal Futures (2022) for SixtyEight Art Institute and the essay ‘A brief constellation towards a ruderal futurism’ (2020).
TROPION-Lung01 Results Indicate PFS Benefit With Datopotamab Deruxtecan Over Docetaxel in Previously Treated Nonsquamous NSCLC: A Critique and a Question
Authors: Bornstein-Quevedo Leticia , Dueñas-Gonzalez Alfonso
Published: October 2024

This commentary aims to point out how the results of the TROPION-LUNG01 study stress the "positive aspects" of the results, specifically, the increase in PFS, but hardly mention the potential harm to patients with squamous histology and lacks information on binary data (progression-free / progression, (alive/death) as per CONSORT guidelines. Here, we also remark on the need for adherence to CONSORT guidelines to inform on the absolute and relative risks of Randomized Controlled Trials (RCT). We emphasize the need for further research to develop a framework of how oncologists might explain the differences between PFS and OS in simple terms for a lay audience to improve a more informed decision of patients to embark on any cancer treatment.
Ethnobotanical Documentation of Yerba Mate in Syria
Authors: Khatib Chadi , Aljbaee Omar
Published: October 2024

ETHNOPHARMACOLOGICAL RELEVANCE: Yerba Mate (_Ilex paraguariensis_) is a traditional herbal beverage consumed for its stimulating effects and health benefits, with a deep cultural association in Syria following its introduction by migrants from South America in the early 20th century. This study documents the cultural, social, and health-related practices surrounding Yerba Mate in Syria, highlighting its integration into local customs and herbal preparations.

OBJECTIVE: To explore and document the traditional uses, social practices, and preparation methods of Yerba Mate among Syrian consumers, and to investigate the health benefits and cultural significance attributed to it.

METHODS: An electronic survey was distributed to 430 participants from different regions across Syria, collecting data on Yerba Mate consumption habits, social practices, reasons for use, perceived effects, and traditional preparation methods. Quantitative and qualitative data were analyzed using statistical software. The Relative Frequency of Citation (RFC) index was used to assess the prevalence of herbal additives in Yerba Mate preparations.

RESULTS: Yerba Mate is consumed regularly by 89.2% of participants, with health benefits being a key motivator for 60% of users. Syrian traditions enhance Yerba Mate with local and imported herbs, with 68.6% of regular drinkers incorporating herbs like wormwood (_Artemisia herba-alba_) and chamomile (_Matricaria chamomilla_), each offering specific health benefits. The survey revealed high consumption patterns, particularly in group settings (51.6%), and frequent daily use by 50% of participants.

CONCLUSION: Yerba Mate has become a deeply rooted part of Syrian culture, with local adaptations that incorporate traditional medicinal herbs. These combinations not only enhance the health benefits of the drink but also reflect a blend of imported traditions with Syrian herbal knowledge. The study highlights Yerba Mate's social significance in Syria and suggests the need for further research into its potential therapeutic uses in traditional medicine. Given the unique Syrian practice of mixing Mate with various herbs, further investigation is needed to assess the differences in effects, flavor, and prevalence among these herbal combinations.
A Scale to Measure Social Media Jealousy
Authors: Krishnan S. Rama Gokula , Sethuramalingam Vellaiah , Chandni S.
Published: October 2024

As social media continues to grow rapidly throughout the world, researchers and mental health professionals have been keenly observing and recording some of its detrimental effects on the mental and emotional health of its users. In this regard, one of the constructs that has been gaining interest is social media jealousy. However, there is a paucity of standardised tools that accurately measure this construct. To fill this gap, the present research was undertaken as a part of a larger study examining the possible negative effects of social media. The present research has resulted in the development of the 15-item Social Media Jealousy Scale (SMJS-15). It is a single-dimensional scale that has shown strong reliability, convergent validity, as well as evidence of construct validity. The scale has been developed using both exploratory and confirmatory factor analyses and can be used to test social media jealousy experienced by users across multiple social media platforms.
The Withdrawal of Soviet Troops from Czechoslovakia
Authors: Kocáb Michael
Published: October 2024

On June 25, 1991, the authorized representatives of the governments of Czechoslovakia and the Soviet Union signed a protocol for the termination of Soviet troops stationed in Czechoslovakian territory. The occupation of Czechoslovakia by the Soviet Army and the ensuing political, ideological, economic and cultural influences of Soviet power over our internal affairs have become a thing of the past, once and for all. The unbelievable bas become a reality. This act took place not against the will of the Soviet government, but in accordance with its resolution that described the entry of the Warsaw Treaty armies into our territory in 1968 as a political mistake. This strengthens the hope that it will be possible to transform the sinister ties amongst the countries of the former Eastern bloc into one built on solid relations, fully respecting state sovereignty and the rights to their own political, cultural and social orientations. The Federal Assembly Commission for Supervision of the Withdrawal of Soviet troops from Czechoslovakia realized three main priorities in its work. First - to follow solutions of the technical aspects of the withdrawal and the adherence to the timetable worked out by the authorized representatives of the two countries. Second - to take part in the preparatory work on an agreement for the settlement of property and financial claims ensuing from the entry, presence and withdrawal of Soviet troops. Third - to strive to transform political, cultural and economic relations with the Soviet Union, and not to contribute to further destabilization of relations amongst the counties of the former Eastern bloc.
Scientific Discussions with American Political Scientists from Stanford on Issues of European Security
Authors: Handl Vladimír , Leška Vladimír
Published: October 2024

In mid-December 1990, at the invitation of the úMV, prominent American political scientists from the Center for International Security and Arms Control at Stanford University in California visited Prague. The delegation was led by professor dr. William Perry, co-director of the center and former undersecretary for research and technology at the US Department of Defense. Its members were professor dr. Michael May, a scientist at the center, and the former director of the Lawrence Livermore National Laboratory for Nuclear Weapons, and professor dr. Robert Hamerton-Kelly, the center's project coordinator.
On December 17 and 18, 1990, the ÚMV held a scientific discussion on current issues of European security with their participation. In addition to the employees of the institute, she is also a member of the Czechoslovak party. attended by doc. dr. Alexandr Ort, DrSc., and then Maj. Gen. ing. Jaroslav Štecha and Col. ing. Jaroslav Němec from FMO. At the suggestion of the American side, the discussion was divided into four thematic areas:1. General European issues.2. Security issues.3. Weapons conversion.4. Ethnic minorities and European security.
Islam: Ideal and Reality
Authors: Kovář Jindřich
Published: October 2024

Under this title, another publication of a group of workers of the CSAV Oriental Institute, dealing with this highly topical issue, was published. Reviewed the book represents the logical culmination of the efforts of our most professional scientific workplace to bring the various aspects and spheres of influence of this world religion closer to the Czech reader. After the previously published books/ which showed how Islam influenced and still influences to a considerable extent the sphere of politics and the place of Muslim states in the world, the authors of the current publication took the step that is probably the most necessary from the point of view of our public, to comprehensively shed light on Islam by itself. It is necessary to say at the outset that they succeeded. The reader got his hands on a book that presents the basic characteristics of Islam in a readable form, explains the main concepts, brings Islamic institutions closer to it, etc. At the same time, the author's collective is based not only on theory and what is written, but also on practice and how the regulations of Islam are practically applied. In this regard, the subtitle of the book Ideal and Reality is really justified. The authors managed to capture different interpretations of the regulations, although they did not get bogged down in excessive details.
New Directions for American Policy in Asia
Authors: Havlíčková Světlana
Published: October 2024

Changes in the politics of the world's great powers continents, regions and individual countries much attention was paid to the species. At one o'clock of such changes, that is, about the change of American politicians see Asia, Bernard's book discusses K. Gordon.' The publication consists of a short introduction, some comprehensive chapters and the conclusion. In the introduction, the author notes that we are on the beginning of a new era in international politics, when ways of politics from the time after the Second World War cylinders can no longer be claimed. Created new ones American policies, especially the formulation of their principles, are also primarily focused on East Asia (hereafter referred to as VA) - however, it is not more precisely defined geographically - somehow the most dynamic area of ​​the world. With developments in this area, the USA must keep up without destroying the favorable conditions that helped to create. Due to the changes in the VA, the USA should formulate a new soy policy for the entire Asian continent.
Úvod
Authors: Pick Otto
Published: October 2024

Prof. dr. O. Pick, předseda redakční rady.
Zpět k bipolárnímu světu?
Authors: Texler Jiří
Published: October 2024

Jiří Texler, nar. 1929, absolvent Vysoké školy věd hospodářských, je ekonom dlouhodobě se zabývající otázkamisvětového hospodářství a úlohou lidského činitele v procesech rozvoje a hospodářského růstu (např. publikace Lidský faktor ekonomické dynamiky, Praha, Academia, 1990). Nyní působí převážně publicisticky a vědecky, mezi jinými v rámci mezinárodního výzkumného programu zaměřeného na interdisciplinární přístupy k otázce rozvoje.
K čs.-německé Smlouvě o dobrém sousedství a přátelské spolupráci
Authors: Kopecký Bedřich
Published: October 2024

Bedřich Kopecký, nar. 1952, vystudoval fakultu mezinárodního práva Moskevského státního institutu mezinárodních vztahů, absolvoval kurs mezinárodního práva soukromého na Haagské akademii mezinárodního práva. V letech 1984-1989 byl III. tajemníkem na čs. zastupitelském úřadu v Bonnu. V současné době je ředitelem 2. teritoriálního odboru FMZV.
Budou v Asii další nově industrializované země?
Authors: Kovář Jindřich
Published: October 2024

Jindřich Kovář, nar. 1935, vystudoval filozofickou fakultu Univerzity Karlovy, od roku 1963 pracuje v oddělení rozvojových zemí ÚMV. Zabývá se zejména otázkami Asie, regionální bezpečnosti a spolupráce.
Směnitelnost měny a transformace na tržní typ ekonomiky
Authors: Hrnčíř Miroslav
Published: October 2024

Miroslav Hrnčíř, nar. 1937, je vědeckým pracovníkem Ekonomického ústavu ČSAV, kde pracuje jako vedoucí týmu pro makroekonomicko-stabilizační politiku a měnovou problematiku. Vydal mnohé knižní i časopisecké práce zejména z oblasti vnějších ekonomických vztahů, měny a měnové politiky, jakož i k problematice transformace čs. ekonomiky.
Documento de trabajo. Clinicas jurídicas en América Latina (protocolos)
Authors: Faundes Peñafiel Juan Jorge , Fernández Miguez Sheila , León Silva Glorimar , Rojas Roncagliolo Gemma , Cid Sandoval Eliada , Avaria Saavedra Andrea , Espinoza Almonacid Camila , Breuer Castillo Thomas , Mardones Ahilla Duban , Pérez Courbis Camila , Valenzuela Rettig Pilar , Rivas Arias Valeska
Published: October 2024

El Proyecto “Clínica Jurídica Intercultural” de la Universidad Autónoma de Chile (UA), FONDEF IDeA, Protocolo de atención clínica-jurídica con perfil intercultural para población migrante e indígena (I+D ID22I10207), es una iniciativa pionera en el ámbito clínico Jurídico en Chile que, en especial, introduce de manera explicita, los enfoques de derechos humanos, de género e intercultural. Este Protocolo se compone de tres instrumentos base: i) “Guía de Actuación Clínica Jurídica Intercultural”; ii) “Propuesta Pedagógica Clínica Jurídica Intercultural”; y iii) APP+web −www.clinicajuridicaintercultural.cl/blank −. A ellos se suman otros trabajos imprescindibles para lograr aquellos. En ese marco se inscribe el presente “Documento de Trabajo. Clínicas jurídicas en América Latina (Protocolos)”. Este Documento de trabajo contiene un necesario e importante esfuerzo de revisión del estado del arte en materia de Clínicas Jurídicas en América Latina y la respectiva sistemación de dicha información que resultó fundamental para poder desarrollar el Protocolo elaborado por la Universidad Autónoma de Chile. Este estudio queda disponible para la comunidad científica pedagógica clínica del derecho, de Chile y América Latina, esperando contribuya a impactar en la formación inclusiva e intercultural de los y las futuros profesionales del Derecho.
Does Physics Need Metaphysics?
Authors: Rush Kathleen
Published: October 2024

A number of thinkers both past and present have been skeptical of the role of metaphysics for science. The early modern philosopher David Hume denigrated metaphysics as an attempt to “penetrate into subjects utterly inaccessible to the understanding,” while the Logical Positivists saw metaphysics as meaningless, wholly useless to scientific inquiry. In contrast to these thinkers stands the early modern philosopher Gottfried Wilhelm Leibniz. A mathematician and scientist himself, Leibniz developed a variety of metaphysical principles entailed centrally by his Principle of Sufficient Reason. Leibniz utilized these principles to address scientific topics of his day, including, but not limited to, the relative nature of space and the heliocentric model of the universe. Drawing on Leibniz’s diverse corpus, I will reconstruct his formulations of the Principle of Sufficient Reason, the Principle of Perfection, and the Principle of the Identity of Indiscernibles, providing the intellectual context for their development. I will then argue through examples that his metaphysical principles illustrate the utility of metaphysics for natural science, for they can be used to both ground the logical coherence of the discipline of physics and serve as practical methodological guides for theory development and selection.
“This Is Exactly the Type of Activity the Museum Should Be Doing All the Time”
Authors: Riotto Elizabeth , Ennes Megan , Melanie Giangreco
Published: October 2024

Recent research suggests that the use of natural history collections in museum education can be beneficial for science engagement and public education. This study expands on this extant research through an exploration of a natural history Live Lab exhibit, in which museum faculty, staff, and volunteers prepared paleontological specimens for collection while engaging the public in science education in an interactive exhibit space. Using a framework of activity theory, a mixed-methods survey was distributed to individuals who participated in the Live Lab to explore the interactions of the subjects, objects, tools, outcomes, rules, and labor division in the Live Lab. Twenty-two (n = 22) individuals responded, and their quantitative and qualitative responses to this survey were openly coded and analyzed. This analysis revealed that participants valued engaging the public with paleontology, believed both themselves and the public benefited from the exhibit, and expressed enthusiasm for future interactive and collections-based exhibits. Conversely, some participants also experienced challenges with the physical Live Lab space, feelings of unpreparedness, and hesitations about personal skills when engaging in public outreach. As such, a future Live Lab or similar collections-based exhibits are recommended alongside greater preparation and training for those staffing the exhibit.
Senior Discount? Gender, Age, and Small Donor Fundraising
Authors: Jeffries Reed , Carlson Lucca
Published: October 2024

Recent discussions surrounding candidate age and its impact on small donor fundraising have raised questions about ageism in American politics. However, existing studies of age in politics largely neglect the specific obstacles encountered by older female candidates.  This paper, which examines the impact of age and gender on small contribution receipts in U.S. House of Representatives campaigns from 2006-2010, aims to address the following questions: How do age and gender interact to predict small contribution receipts? What are the implications for fundraising of older women candidates compared to their male counterparts? The findings reveal a significant negative interaction between age and gender, indicating that older female candidates experience a pronounced reduction in small contribution receipts compared to older male candidates. This suggests that age-related biases intersect with gender, posing unique challenges for older women candidates in fundraising efforts.
Vocabulary Acquisition in Beginner L2 Learners
Authors: Julia Charske  , Landaeta Andrea , Puscama M. Gabriela
Published: October 2024

This project focuses on how different vocabulary teaching methods may develop efficient lexical-semantic networks in L2 learners. Vocabulary that frequently co-occurs in the environment becomes associated in the lexicon (e.g., food + sports) and it strengthens the representation of vocabulary. This experiment tests the effect of co-occurrence presentation and thematic list presentation on vocabulary processing. The goal is to inform vocabulary teaching methods. L2 learners completed a pre-test, four sessions of vocabulary training, and an immediate post-test. During training sessions, participants saw images on a computer and reviewed Spanish vocabulary, under one of two conditions: one word presented at a time in thematic lists (e.g., food), or words displayed in a visual scene or context (e.g., dinner party). During testing, participants completed a picture naming task to assess how different types of vocabulary exposure impacts L2 processing. Other individual differences such as working memory and proficiency were collected as well. The results from the picture naming task show that effectiveness of training in thematic list (TL) verse visual scene (VS) depended on initial proficiency and working memory. Participants with a higher initial proficiency and working memory improved more when trained with the VS condition, while those with lower proficiency and working memory had greater success when trained via the TL condition.
Research on the social functions of trade to support the development of marketability of farm products
Authors: Nikishin A. F. , Karashсhuk O. S. , Mayorova E. A. , Boldiasov A. I.
Published: October 2024

In recent years, there has been a problem of reducing the marketability of agricultural products of farms for many types of goods. Among the key food products supplied by farmers, the negative dynamics of sales was noted for the sale of potatoes and vegetables. This situation is largely related to the annual fluctuations in agricultural production, which is especially evident in the cultivation of fruit and vegetable crops. Using econometric modeling based on the construction of regressions based on panel data, the article shows the negative impact of changes in production volumes on the percentage of marketability of farm products. Farmers, like other small-scale enterprises, do not have a developed marketing infrastructure, unlike agricultural organizations. Therefore, farms are particularly sensitive to fluctuations in production volumes, which create for them the problem of lack or excess of resources for sales. An important way to solve this problem is the activity of trade organizations aimed at implementing social functions to support the sale of farm products. In Russia, such social practices are being implemented by the largest representatives of the retail industry in a pilot mode in certain regions of the country. In particular, in some areas, agricultural aggregators are operating, launched by the “X5 Group” and “Magnit” retail chains, which perform technological and marketing functions to ensure the sale of farm goods. There are other social projects of trade organizations, for example, “Agrocontract” and “Farmer›s Island”, initiated by “X5 Group”, which involve the conclusion of direct contracts with farmers in order to reduce the purchase prices of goods and provide for the purchase of various unique goods from farmers. The expansion of the social functions of trade organizations will significantly overcome the existing problems of marketing farm products and provide such farms with sufficient income and profit for further self-development of activities.
Bibliometric analysis of scientific publications on the websites of agricultural institutions of higher and additional education of the Russian Federation
Authors: Nepochatykh A. Yu. , Timofeevskaya S. A.
Published: October 2024

The study of scientific activities of educational institutions of the agro-industrial complex is based on information from their websites and on scientometric indicators. Research work is reflected on all the studied websites and contains data on the topics of scientific research, the work of dissertation councils and data on patents and inventions. The electronic information environment is widely used, digital libraries are being developed, and links to digital library systems are provided. All higher educational institutions have scientific periodicals; the results of scientific research are presented in electronic form. Insufficient completeness of document archives, the spread of materials across the categories of the website, and limited availability of full-text databases are noted. An analysis of the publication activity of organizations was conducted on the basis of the Russian Science Citation Index (RSCI). According to the number of authors with publications in the RSCI, Russian Timiryazev State Agrarian University, Kuban State Agrarian University named after I.T. Trubilin and Vyatka State Agrotechnological University are distinguished with 3219, 300 and 1520 authors, respectively. Publications of employees of the Kuban State Agrarian University, Russian Timiryazev State Agrarian University, Omsk State Agrarian University named after P.A. Stolypin and Ryazan State Agrotechnological University named after P.A. Kostychev have a high citation rate in RSCI. When analysing the dynamics of the number of publications of educational institutions from 2019 to 2023, according to RSCI data, a general trend of increasing the number of scientific publications in agrarian universities was revealed.
Level of prooxidant-antioxidant status in highly productive cows with comorbid obstetric, gynecological and orthopedic pathology
Authors: Lutsaу V. I. , Sibirtsev V. D. , Nefedov A. M. , Rudenko P. A.
Published: October 2024

The lipid peroxidation and antioxidant defense system is a balanced system responsible for the processing and utilization of lipids in the body’s cells. It plays an important role in lipid metabolism, cell protection and overall health of the body. Its proper functioning is necessary to ensure optimal functioning of cells and organs throughout the body. The article clinically and experimentally substantiates the pathogenetic role of lipid peroxidation products and the level of antioxidant protection in cows with endometritis and purulent-necrotic processes in the finger area, as well as with the comorbid course of endometritis and orthopedic pathology. It has been shown that multimorbid manifestation is accompanied by a more severe course than individual diseases. It has been established that the development of postpartum endometritis and purulent-necrotic lesions of the limbs in cows is accompanied by a highly significant increase in lipid peroxidation products in the blood serum against the background of a decrease in the amount of antioxidant enzymes, with the exception of ceruloplasmin. Moreover, these changes are accompanied by a sharp jump in the comorbid course of endometritis and orthopedic pathology in highly productive animals.
The influence of drugs containing gluconolactone on the morphological parameters of the blood of rabbits
Authors: Gusarova A. V. , Ivanishchev K. A. , Lyashchuk Yu. O. , Ovchinnikov A. Yu. , Samarin G. N.
Published: October 2024

The work is devoted to the issues of using polyhydroxy acids in rabbit breeding. Antioxidants are extremely important compounds for living organisms. The authors considered the effect of gluconolactone used in the animal diet on the metabolic processes and physiological indicators of life activity of rabbits. Based on the studies (using gluconolactone as an example), the advisability of including supplements containing polyhydroxy acids in the rabbit diet is shown. Polyhydroxy acids, which are antioxidants, when regularly introduced with feed, help to increase the overall resistance of the body, stimulate the growth and healthy development of animals, which in turn leads to obtaining high-quality agricultural products. Rabbits, like other animals, can obtain antioxidants from plant foods, but their concentration may be insufficient for full protection against oxidative stress. To stabilize feed rations, various biologically active additives are used, which make it possible to increase the efficiency of animal rearing and improve productivity indicators. Thus, polyhydroxy acids, in particular gluconolactone, are well suited for sensitive animals that require the utmost care and gentle rearing.
Study of the dynamics of relative expression of the EGR1 gene in rainbow trout in different tissues
Authors: Shcherbackov Yu. S. , Nikolaeva O. A. , Tyshchenko V. I.
Published: October 2024

The purpose of this study was to study the dynamics of the comparative level of expression of the EGR1 gene in the tissues of rainbow trout at different ages. The EGR1 gene encodes a transcription factor that influences the transcription of a large number of genes from both the 5-bar and 3-bar ends of genes. A random sample of fish aged 6, 12 and 18 months was taken for the study. To assess the expression level of the EGR1 gene, located on 14 chromosomes, a housekeeping gene was taken: G6PD. A comparative analysis of the expression level of the EGR1 gene in rectal tissues revealed a significant change in different age periods of rainbow trout. Expression in the tissues of the rectum at the age of 6 months was maximal, and at the age of 12 months it was minimal, but no significant differences were found (p = 0.2648). As a result of the analysis of changes in the level of relative expression of the EGR1 gene in the heart tissues of rainbow trout at different ages, it was found that in the group of fish aged 6 months, the expression level was maximum at the stage of 12 and 18 months (р < 0.01). As a result of the study, a correlation between the size and weight parameters of rainbow trout and the level of gene expression in different eras and in different countries was established. Expression dynamics at different ages in rainbow trout were also determined.
Boas Práticas Higiênicas: estudo comparativo em supermercados de Piraquara - PR após oficinas de capacitação
Authors: Couto Fernanda Siqueira , Torres Fernanda Paula Silva , Gonzales Ingridy Fhadine Hartmann , Haisi Amanda , Constantino Caroline , Balbino Elizabete Javorouski , Lopes Marcia Oliveira
Published: October 2024

A adesão às Boas Práticas Higiênicas no varejo é imprescindível para a oferta de alimentos seguros. Objetivou-se avaliar a adesão às boas práticas higiênicas em supermercados antes e após ações educativas para gerentes e manipuladores de alimentos. Para isso, compararam-se dados de 18 supermercados por meio de uma lista de checagem de Boas Práticas Higiênicas, antes e após a realização de oficinas de capacitação. Os resultados demonstraram um aumento na adesão às Boas Práticas Higiênicas após as oficinas educativas e ressaltaram a importância da educação em saúde na mudança de ações, contribuindo para a oferta de alimentos seguros.
دليل إثبات وجود العقل المجرد عند نصير الدين الطوسي: قراءة تحليلية
Authors: Türkmen Ersan
Published: October 2024

تتناول هذه الدراسة تحليل الأدلة التي استخدمها نصير الدين الطوسي (ت. 672/1274) في إثبات العقل المجرد. ولكون طريق الإثبات الموجودة عند الطوسي مبنية على طرق فلاسفة ومفكري ما قبل الطوسي، قمنا بتحليل تلك الطرق لأجل إضفاء الوضوح على دليل الطوسي. حينما نقرأ التاريخ الفلسفي الإسلامي، نجد أنّ مصطلح العقل في بداية استخدامه الفلسفي، كان يؤدي معنا معرفيا بالذات، إلا أنّه مع مرور الزمن أخذ هذا المصطلح منحا وجوديا. فعلى سبيل المثال، استخدم فلاسفة مثل الفارابي (ت. 339/950) وابن سينا (ت. 428/1037) العقل بمعنى أنطولوجي، مع قبولهم لما يحتويه مصطلح العقل من الناحية الوظيفية لمعاني الإدراك والمعرفة، حيث أنّهم قالوا بكونه مبدأ أو علة للوجود. والسبب في ذلك هو أنّ هذين الفيلسوفين خاصة يفسران الوجود بناء على نظرية الفيض. لكنّ الفلاسفة مع تكلمهم عن العقل بهذا المعنى، تطرقوا الى مسألة وجوده وحاولوا إثباته بطرق مختلفة. خاصة وأنّ الفلاسفة المذكورين أعلاه فسروا العقل بالتمسك بنظرية الفيض، كما أثبتوا وجوده بناء على نفس النظرية. إنّ الطوسي من حيث بنيته الفلسفية، يُعتبر من المفكرين الذين تأثروا بالفلاسفة المشائين عمومًا كابن سينا، ولكنّه مع هذا يختلف عنهم جزئيًا، خاصة في سياق الوجود ومبادئه. لكون الطوسي ينتقد نظرية الفيض الإلهية التي طورها ابن سينا لتفسير الوجود. ولأجل هذا السبب ايضا، فهو ينتقد الأدلة التي استخدمها ابن سينا لإثبات وجود العقل المجرد الموجود ضمن تلك النظرية. وعلى الرغم من انتقاده لهذه الأدلة، وخاصة في كتابه تجريد الاعتقاد، إلا أنّه يقبل بشكل عام وجود العقل المجرد، ولإثبات وجوده، يستخدم أدلة مختلفة عمّا هو موجود عند ابن سينا. إنّ الطوسي قد خصّص رسالة مختصرة مستقلة لإثبات وجود العقل المجرد، فهو قد حاول إثبات هذا النوع من العقل في تلك الرسالة، من دليل متكون من ثماني مقدّمات. إنّ الدليل الذي يستخدمه الطوسي في هذا المجال، دليل معرفي في أساسه، لأنّه يرى بأنّ العقل المجرد هو مصدر الصور العقلية، ويسميه أحيانًا نفس الأمر. ولهذا السبب فبحسب الطوسي، لا يمكن إثبات وجود ذلك العقل إلا من خلال الانطلاق من الصور العقلية والمبادئ المعرفية التي يمكن للبشر إدراكها. فإنّ تلك المفاهيم والمبادئ المعرفية المُسلّم بها، لا يمكن أن تكون صحيحة إلّا بوجود مبدأ خارجي يُقاس عليها، ومن ثم فهو يرى أنّ المعيار في صحة هذه المبادئ هو العقل المجرد. لو نظرنا الى إثبات الطوسي لهذا النوع من العقل من الناحية المعرفية، فإنّنا نجده محوالا لإثبات صدق المعلومات البديهية أيضا. فمن هذا المنطلق يمكننا القول بأنّ هدفه في دليله هذا ليس فقط إثبات العقل المجرد، بل أيضا هو محاولة لإثبات صدق المعلومات الأولية. كما أنّ أغلب المقدمات التي تُشكّل دليل الطوسي هذا، موجودة في كتب الفلاسفة السابقين بأشكال مختلفة، إلا أنّه من الممكن القول بأنّها أصلية من حيث التأليف البرهاني. في الحقيقة ان أهمية هذا البحث تكمن في هذه المسألة، حيث إنّه يسلط الضوء على مسألة إمكانية إثبات العقل المجرد عن طريق معرفي صرف.
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