bluuebunny/crossref_metadata_2025 huggingface dataset:
Solubility and Thermodynamic Analysis of Isotretinoin in Different (DMSO + Water) Mixtures
Authors: Shakeel Faiyaz , Haq Nazrul , Alshehri Sultan , Alenazi Miteb , Alwhaibi Abdulrahman , Alsarra Ibrahim A.
Published: October 2023

The solubility and solution thermodynamics of isotretinoin (ITN) (3) in numerous {dimethyl sulfoxide (DMSO) (1) + water (H2O) (2)} combinations were studied at 298.2–318.2 K under fixed atmospheric pressure of 101.1 kPa. A shake flask methodology was used to determine ITN solubility, and correlations were made using the “van’t Hoff, Apelblat, Buchowski-Ksiazczak λh, Yalkowsky-Roseman, Jouyban-Acree, and Jouyban-Acree-van’t Hoff models”. In mixtures of {(DMSO (1) + H2O (2)}, the solubility of ITN in mole fractions was enhanced with the temperature and DMSO mass fraction. The mole fraction solubility of ITN was highest in neat DMSO (1.02 × 10−1 at 318.2 K) and lowest in pure H2O (3.14 × 10−7 at 298.2 K). The output of computational models revealed good relationships between the solubility data from the experiments. The dissolution of ITN was “endothermic and entropy-driven” in all of the {(DMSO (1) + H2O (2)} mixtures examined, according to the positive values of measured thermodynamic parameters. Enthalpy was discovered to be the driving force behind ITN solvation in {(DMSO (1) + H2O (2)} combinations. ITN-DMSO displayed the highest molecular interactions when compared to ITN-H2O. The outcomes of this study suggest that DMSO has a great potential for solubilizing ITN in H2O.
Assessing the In Vitro and In Vivo Performance of L-Carnitine-Loaded Nanoparticles in Combating Obesity
Authors: Uner Burcu , Ergin Ahmet Dogan , Ansari Irfan Aamer , Macit-Celebi Melahat Sedanur , Ansari Siddique Akber , Kahtani Hamad M. Al
Published: October 2023

Addressing obesity is a critical health concern of the century, necessitating urgent attention. L-carnitine (LC), an essential water-soluble compound, plays a pivotal role in lipid breakdown via β-oxidation and facilitates the transport of long-chain fatty acids across mitochondrial membranes. However, LC’s high hydrophilicity poses challenges to its diffusion through bilayers, resulting in limited bioavailability, a short half-life, and a lack of storage within the body, mandating frequent dosing. In our research, we developed LC-loaded nanoparticle lipid carriers (LC-NLCs) using economically viable and tissue-localized nanostructured lipid carriers (NLCs) to address these limitations. Employing the central composite design model, we optimized the formulation, employing the high-pressure homogenization (HPH) method and incorporating Poloxamer® 407 (surfactant), Compritol® 888 ATO (solid lipid), and oleic acid (liquid oil). A comprehensive assessment of nanoparticle physical attributes was performed, and an open-field test (OFT) was conducted on rats. We employed immunofluorescence assays targeting CRP and PPAR-γ, along with an in vivo rat study utilizing an isolated fat cell line to assess adipogenesis. The optimal formulation, with an average size of 76.4 ± 3.4 nm, was selected due to its significant efficacy in activating the PPAR-γ pathway. Our findings from the OFT revealed noteworthy impacts of LC-NLC formulations (0.1 mg/mL and 0.2 mg/mL) on adipocyte cells, surpassing regular L-carnitine formulations’ effects (0.1 mg/mL and 0.2 mg/mL) by 169.26% and 156.63%, respectively (p < 0.05).
Evolution and Trends in Sign Language Avatar Systems: Unveiling a 40-Year Journey via Systematic Review
Authors: Aziz Maryam , Othman Achraf
Published: October 2023

Sign language (SL) avatar systems aid communication between the hearing and deaf communities. Despite technological progress, there is a lack of a standardized avatar development framework. This paper offers a systematic review of SL avatar systems spanning from 1982 to 2022. Using PRISMA guidelines, we shortlisted 47 papers from an initial 1765, focusing on sign synthesis techniques, corpora, design strategies, and facial expression methods. We also discuss both objective and subjective evaluation methodologies. Our findings highlight key trends and suggest new research avenues for improving SL avatars.
Classification of High-Altitude Flying Objects Based on Radiation Characteristics with Attention-Convolutional Neural Network and Gated Recurrent Unit Network
Authors: Dai Deen , Cao Lihua , Liu Yangfan , Wang Yao , Wu Zhaolong
Published: October 2023

In the task of classifying high-altitude flying objects, due to the limitations of the target flight altitude, there are issues such as insufficient contour information, low contrast, and fewer pixels in the target objects obtained through infrared detection technology, making it challenging to accurately classify them. In order to improve the classification performance and achieve the effective classification of the targets, this study proposes a high-altitude flying object classification algorithm based on radiation characteristic data. The target images are obtained through an infrared camera, and the radiation characteristics of the targets are measured using radiation characteristic measurement techniques. The classification is performed using an attention-based convolutional neural network (CNN) and gated recurrent unit (GRU) (referred to as ACGRU). In ACGRU, CNN-GRU and GRU-CNN networks are used to extract vectorized radiation characteristic data. The raw data are processed using Highway Network, and SoftMax is used for high-altitude flying object classification. The classification accuracy of ACGRU reaches 94.8%, and the F1 score reaches 93.9%. To verify the generalization performance of the model, comparative experiments and significance analysis were conducted with other algorithms on radiation characteristic datasets and 17 multidimensional time series datasets from UEA. The results show that the proposed ACGRU algorithm performs excellently in the task of high-altitude flying object classification based on radiation characteristics.
Non-Invasive Assessment of Back Surface Topography: Technologies, Techniques and Clinical Utility
Authors: Mehta Bhavna , Chockalingam Nachiappan , Shannon Thomas , Jevtic Nikola , Lazic Filip , Jasani Vinay , Eddison Nicola , Healy Aoife , Needham Robert
Published: October 2023

(1) Background: Frequent exposure to ionising radiation is often used to determine the diagnosis of adolescent idiopathic scoliosis (AIS), a lateral curvature of the spine in those aged between 10 and 18 years, and a treatment plan according to Cobb angle. This narrative review outlines the clinical utility of surface topography (ST), a radiation-free imaging modality. (2) Methods: Publicly available databases were searched to yield literature related to ST. Identified articles were classified based on the equipment used and in order of how it was developed, i.e., historical, recent developments, and state-of-the-art developments. (3) Conclusions: ST is a reliable cost-effective non-invasive technique that provides an alternative to radiation-based imaging to aid with the diagnosis and potential screening of AIS. Several scanning methods are available, which allows ST to be used in several clinical environments. Limitations of inter-reliability and differences of apparatus resulting in variations of data have been noted through this narrative review.
Underwater Source Counting with Local-Confidence-Level-Enhanced Density Clustering
Authors: Chen Yang , Xue Yuanzhi , Wang Rui , Zhang Guangyuan
Published: October 2023

Source counting is the key procedure of autonomous detection for underwater unmanned platforms. A source counting method with local-confidence-level-enhanced density clustering using a single acoustic vector sensor (AVS) is proposed in this paper. The short-time Fourier transforms (STFT) of the sound pressure and vibration velocity measured by the AVS are first calculated, and a data set is established with the direction of arrivals (DOAs) estimated from all of the time–frequency points. Then, the density clustering algorithm is used to classify the DOAs in the data set, with which the number of the clusters and the cluster centers are obtained as the source number and the DOA estimations, respectively. In particular, the local confidence level is adopted to weigh the density of each DOA data point to highlight samples with the dominant sources and downplay those without, so that the differences in densities for the cluster centers and sidelobes are increased. Therefore, the performance of the density clustering algorithm is improved, leading to an improved source counting accuracy. Experimental results reveal that the enhanced source counting method achieves a better source counting performance than that of basic density clustering.
A Convolutional Neural Network with Spatial Location Integration for Nearshore Water Depth Inversion
Authors: He Chunlong , Jiang Qigang , Tao Guofang , Zhang Zhenchao
Published: October 2023

Nearshore water depth plays a crucial role in scientific research, navigation management, coastal zone protection, and coastal disaster mitigation. This study aims to address the challenge of insufficient feature extraction from remote sensing data in nearshore water depth inversion. To achieve this, a convolutional neural network with spatial location integration (CNN-SLI) is proposed. The CNN-SLI is designed to extract deep features from remote sensing data by considering the spatial dimension. In this approach, the spatial location information of pixels is utilized as two additional channels, which are concatenated with the input feature image. The resulting concatenated image data are then used as the input for the convolutional neural network. Using GF-6 remote sensing images and measured water depth data from electronic nautical charts, a nearshore water depth inversion experiment was conducted in the waters near Nanshan Port. The results of the proposed method were compared with those of the Lyzenga, MLP, and CNN models. The CNN-SLI model demonstrated outstanding performance in water depth inversion, with impressive metrics: an RMSE of 1.34 m, MAE of 0.94 m, and R2 of 0.97. It outperformed all other models in terms of overall inversion accuracy and regression fit. Regardless of the water depth intervals, CNN-SLI consistently achieved the lowest RMSE and MAE values, indicating excellent performance in both shallow and deep waters. Comparative analysis with Kriging confirmed that the CNN-SLI model best matched the interpolated water depth, further establishing its superiority over the Lyzenga, MLP, and CNN models. Notably, in this study area, the CNN-SLI model exhibited significant performance advantages when trained with at least 250 samples, resulting in optimal inversion results. Accuracy evaluation on an independent dataset shows that the CNN-SLI model has better generalization ability than the Lyzenga, MLP, and CNN models under different conditions. These results demonstrate the superiority of CNN-SLI for nearshore water depth inversion and highlight the importance of integrating spatial location information into convolutional neural networks for improved performance.
Instrumentation for Verification of Shunt Active Power Filter Algorithms
Authors: Baros Jan , Bilik Petr , Jaros Rene , Danys Lukas , Strossa Jan , Hlavaty Lukas , Martinek Radek
Published: October 2023

This article presents a comprehensive system for testing and verifying shunt active power filter control methods. The aim of this experimental platform is to provide tools to a user to objectively compare the individual control methods. The functionality of the system was verified on a hardware platform using least mean squares and recursive least squares algorithms. In the experiments, an average relative suppression of the total harmonic distortion of 22% was achieved. This article describes the principle of the shunt active power filter, the used experimental platform of the controlled current injection source, its control system based on virtual instrumentation and control software and ends with experimental verification. The discussion of the paper outlines the extension of the experimental platform with the cRIO RTOS control system to reduce the latency of reference current generation and further planned research including motivation.
Determination of the Relationship between the Granulometry and Release of Polyphenols Using LC-UV, and Their Antioxidant Activity of the Pulp Powder of the Moroccan Argan Tree, “Argania spinosa L.”
Authors: Mourjane Ayoub , Hanine Hafida , El Adnany El Mustapha , Ouhammou Mourad , Bitar Khalid , Mahrouz Mostafa , Boumendjel Ahcene
Published: October 2023

The bioavailability of cosmetic, pharmaceutical, nutraceutical, and food preparations depends, among other factors, on the galenic form and the control of the granulometric structure of powders. The present study aimed to evaluate the effect of argan pulp powder particle size on functional, physicochemical properties, and antioxidant bioactivity. The particle size study revealed a unimodal particle volume distribution, explaining the regular particle shape. The results relating to functional properties indicated that the critical fraction was in the range of 50–125 µm. However, the study of the particles in each class, evaluated via SEM, showed that the morphology of the pulp powder was strongly dependent on the degree of grinding. The classes in the range of 50–125 µm had the highest polyphenol content, while those of <25 µm had the highest flavonoid content (893.33 mg GAE/100 g DW and 128.67 mg CE/100 g DW, respectively). Molecular analysis via LC and GC-MS showed that particle size had a significant effect on the release of bioactive molecules. ABTS, DPPH, and TAC tests showed that the fraction, ‘‘50–125 µm’’, had the highest antioxidant activity. However, the FRAP test showed highest antioxidant activity for particles of <25 µm. The analysis of the bioactive compounds of the argan pulp powder confirmed a differential distribution, depending on the size of the particles.
SPECT/CT Radiomics for Differentiating between Enchondroma and Grade I Chondrosarcoma
Authors: Yoon Hyukjin , Choi Woo Hee , Joo Min Wook , Ha Seunggyun , Chung Yong-An
Published: October 2023

This study was performed to assess the value of SPECT/CT radiomics parameters in differentiating enchondroma and atypical cartilaginous tumors (ACTs) located in the long bones. Quantitative HDP SPECT/CT data of 49 patients with enchondromas or ACTs in the long bones were retrospectively reviewed. Patients were randomly split into training (n = 32) and test (n = 17) data, and SPECT/CT radiomics parameters were extracted. In training data, LASSO was employed for feature reduction. Selected parameters were compared with classic quantitative parameters for the prediction of diagnosis. Significant parameters from training data were again tested in the test data. A total of 12 (37.5%) and 6 (35.2%) patients were diagnosed as ACTs in training and test data, respectively. LASSO regression selected two radiomics features, zone-length non-uniformity for zone (ZLNUGLZLM) and coarseness for neighborhood grey-level difference (CoarsenessNGLDM). Multivariate analysis revealed higher ZLNUGLZLM as the only significant independent factor for the prediction of ACTs, with sensitivity and specificity of 85.0% and 58.3%, respectively, with a cut-off value of 191.26. In test data, higher ZLNUGLZLM was again associated with the diagnosis of ACTs, with sensitivity and specificity of 83.3% and 90.9%, respectively. HDP SPECT/CT radiomics may provide added value for differentiating between enchondromas and ACTs.
Using Driving-Cycle Data to Retrofit and Electrify Sub-Saharan Africa’s Existing Minibus Taxis for a Circular Economy
Authors: Lacock Stephan , du Plessis Armand André , Booysen Marthinus Johannes
Published: October 2023

The nascent electrification of transport has heralded a new chapter in the driving force of mobility. Developing regions such as sub-Saharan Africa already lag in this transformative transport transition. A potential transitional step towards full-scale electric mobility is the retrofitting of the existing fleet of internal combustion-based vehicles. This paper proposes a novel approach to the design of a retrofit electric drivetrain for an internal combustion engine vehicle. Specifically, a minibus taxi, which dominates the region’s informal paratransit industry, is electrified. This retrofit is the first formal research presented with a focus on sub-Saharan Africa and its unique challenges. A generic methodology is presented to systematically specify and select drivetrain components and assess the suitability and characteristics of those components. Unique about the presented methodology is the application of driving-cycle data of internal combustion engine vehicles, which provides quantitative insights into the performance and characteristics of the selected components for a retrofit. Finally, a real-world use case is presented to provide a tangible example and to validate the feasibility of the presented approach.
Introduction of nursing technologies in medical organizations in the samara region
Authors:   SBHI Samara Regional Clinical Oncology Center, Samara, Russia, Pyatikop V. M.
Published: October 2023

The article presents the experience of introducing nursing technologies in medical organizations of the Samara Region. The need for and importance of creating program modules for continuous professional education is emphasized.
Meeting the patient»s expectations — as a result of effective nursing organizations
Authors:   Federal State Budgetary Educational Institution of Higher Education «Samara State Medical University» of the Ministry of Healthcare of Russia, Samara, Russia, Ekimova N. A.
Published: October 2023

Often the patient’s expectations at the stages of treatment are too high. Patients hope that the problems will be resolved in a few days, a maximum of a week, without assessing the course of the disease or the process of treatment and rehabilitation. According to statistics, 75 % of the Russian population seek medical help in a «neglected» state. The article describes the experience of building relationships between a patient and a nurse at the Federal Center for Cardiovascular Surgery in Astrakhan.
Fashion and Temporality: Toward a Problem Statement
Authors:   Orel State University named after I.S. Turgenev, Kovalеva E. V.
Published: October 2023

The article raises the problem of the relationship between fashion as a phenomenon expressing a change in aesthetic preferences in the field of image, leisure and temporality. It also analyzes the previous experience of considering this problem by European thinkers - Simmel, Tarde, Benjamin, Lipovetsky, whose statements about fashion act as the subject of research.
Conservatism: development prospects in the context of the formation of a new Russian statehood
Authors:   Orel State University named after I.S. Turgenev, Starostenko K.V.
Published: October 2023

The article discusses the problems and prospects of the development of conservatism in modern Russia in the aspect of the formation of a new statehood. According to the author, conservatism can become the most optimal idea today, contributing to the unification of the principles of various currents of political thought in its doctrine, contributing to the formation of a strong state that traditionally provides stability, order and prosperity to Russian society.
Problems of the humanitarian component in higher education
Authors:   Orel State University named after I.S. Turgenev, Kononova E.S. , Filina E.D. ,   Teacher of the Mezen Pedagogical College
Published: October 2023

The article presents an overview of some aspects and problem areas of the humanitarian content of Russian university education. In particular, the analysis of such issues as: the place of the «humanitarian component» in the system of higher education; the formation and upbringing of the qualities of a highly moral personality of a student in modern conditions; the formation of professional competencies of humanities within the framework of the Bologna Agreements; the search for ways to integrate humanities and natural sciences, transdisciplinarity, metasubject nature of the humanities; the relationship between socio-humanitarian and technical education, opportunities for humanitarian education of an engineer. At the end, possible ways to overcome the humanitarian crisis in higher education are proposed.
On the heterogeneity of the composition of philosophical concepts and the hypothetical nature of their starting points
Authors:   Орловский государственный аграрный университет им. Н.В.Парахина, Finogentov V. N.
Published: October 2023

The article shows that any deep and meaningful discussion of the question of the composition of philosophical concepts is possible only with the implementation of a differentiated approach to understanding philosophy. So, if we understand philosophy as a special science, then knowledge and opinions will dominate in the composition of the corresponding philosophical concepts. If we understand philosophy as a kind of art, then beliefs and opinions will be represented in its composition first of all. Understanding philosophy as the most rationalized worldview (this is the understanding defended by the author of the article) requires recognition of the presence of two main components in philosophy: knowledge and value-semantic. Accordingly, such an understanding of philosophy is identical to the recognition that philosophical concepts include not only opinions and knowledge, but also beliefs, beliefs, value orientations and ideals. The article also substantiates that the initial provisions (principles) of philosophical concepts, as a rule, have a hypothetical character.
The phenomenon of conformism in the views of representatives of the Frankfurt school
Authors:   Ural Federal University named after the First President of Russia B.N. Yeltsin, Mysovskikh L.O.
Published: October 2023

The subject of this article is the views on the phenomenon of conformism expressed in the works of representatives of the Frankfurt school: Max Horkheimer, Theodor Adorno, Herbert Marcuse and Erich Fromm. The transformation of the interpretation of the phenomenon of conformity in the studied works is traced. Based on the views of the thinkers of the Frankfurt school, some patterns and features of the conformal behavior of the individual are deduced. The author comes to the conclusion that the phenomenon of conformity can be considered as an adaptation of human behavior to the norms, rules and attitudes prevailing in society. Conformism as a form of social behavior can be interconnected with various violations in the system of social order. The ambivalence of conformity is that conformal behavior can lead to both constructive and destructive consequences. At the same time, representatives of the Frankfurt school focus their attention mainly on the destructive side of conformity, giving it a negative assessment, since the conformist behavior of the individual comes mainly from coercion. An individual forced to conformism, not realizing why he agrees with the imposed course of action, adapts to incomprehensible and unacceptable social attitudes for him, turns out to be carrying out destructive activities.
La gamificación como herramienta para la enseñanza y aprendizaje
Authors: Bolaños Jurado Janeth Paola
Published: October 2023

Es conveniente enfocar las metodologías para mejorar el desempeño académico de los estudiantes, y así poder incrementar la motivación por el aprendizaje. Por ello, el objetivo del estudio fue analizar a la gamificación como herramienta tecnológica en el desempeño académico de estudiantes usando plataformas digitales. Se empleó una metodología cuantitativa de tipo descriptivo, diseño no experimental; como técnica se usó la encuesta, como instrumento el cuestionario contentivo con 10 preguntas bajo la escala de Likert. Como resultado se obtuvo que el 71% de los padres encuestados estuvieron Muy de acuerdo en que es necesario aplicar la gamificación como una alternativa para mejorar el desempeño de los estudiantes, mientras que un 27% estuvo “De acuerdo” en que se aplicaran y un 2% se mantuvo indiferente. En conclusión, la gamificación como herramienta tecnológica tiene un impacto positivo en el desempeño académico. Existe una tendencia creciente hacia la integración de la gamificación en el entorno educativo, lo cual demuestra la importancia de adoptar enfoques innovadores y adaptados a las necesidades de los estudiantes en su proceso de aprendizaje.
Modular Distance Learning in the New Normal: Challenges on its Implementation
Authors: Junpel Acut
Published: October 2023

This basic research was conducted to determine the challenges of teachers in the implementation of modular distance learning in the new normal of the public elementary and secondary schools in the District of Gitagum, Division of Misamis Oriental. Specifically, it sought to: a) describe the characteristics of the respondents; b) determine the challenges encountered by the teachers in terms of accessibility, availability of resources, support to learners, teachers’ competence and teaching strategies, assessment, and health and safety measures; c) determine the significant relationship between the respondents’ challenges and their characteristics;  and d) come up with an intervention plan based on the results of the study. The respondents of the study were the one hundred five (144) public school teachers in the  District of Gitagum, Division of Misamis Oriental. A researcher-made survey questionnaire was employed to obtain specific information about the study. The data were analyzed using descriptive statistics such as frequency counting of data, percentage, mean and standard deviation. Pearson Product Moment of Correlation was employed to test the significant relationship between the respondent’s challenges and their characteristics. An intervention plan was designed to help teachers in finding solutions to the challenges they are facing in the implementation of modular distance learning. The teachers’ challenges were low in the implementation of modular distance learning. It suggests that teachers faced few challenges or that the challenges they encountered were of low intensity. In other words, it implies that teachers found it relatively manageable to implement modular distance learning, and the difficulties they encountered were not severe. Teachers’ challenges were significant to sex, position, teaching experience and attitudes towards modular distance learning in the new normal. It is recommended that teachers seek support from stakeholders and the local government to acquire funds for better implementation.
Text Messaging in English and Arabic with Reference to Translation
Authors: Adel Nouri Ahmed , Ali Hussein Omar
Published: October 2023

In the twenty-first century, many people now live their lives through text messaging. In fact, you can witness people using their cell phones to send character-based messages to their friends, classmates, family members, and coworkers in malls, schools, and pretty much anywhere else. The popularity of this method of communication has increased particularly among young people. One benefit is that technology enables people to speak with others virtually anywhere. Second, it enables individuals to speak softly, which is useful in noisy places like bars, where it would be challenging to have a productive conversation over the phone, or when extraneous communication needs to be done quietly, such as in a school. Thirdly, it combines some of the advantages of phone and email communication by allowing them to communicate both synchronously (i.e., two-way communication occurs concurrently) and asynchronously (i.e., two-way communication is delayed). The usage of acronyms, abbreviations, and other shorthand notations has become commonplace in this technology's creation of a new language form. The focus of this research is on these qualities specifically and how they are used. The aim of this study was to analyze not only how frequently but also how these symbolic expressions are used in relation to the linguistic functions that they signal, which was followed by a number of discoveries.
Death of Hero in Othello (1603) and Romeo and Juliet (1595): Death and Dying Studies in English Literature
Authors: Rauf Ramis , Rezkiawan Faida Fardan , Ulya Afriani , Mutmainnah Mutmainnah , Harianto Eko
Published: October 2023

This research focuses on the hero's death in two Shakespearean plays, Othello and Romeo and Juliet. It attempts to answer how the author depicts death and dying in Shakespeare's plays. Benstock and Dickinson, two specialists on death and dying, will provide an answer to the challenge. Benstock divides the death stages into three categories: deceased, moribund, and living-dead. Simultaneously, Dickinson mentions three periods of life: children strove (early life), gazing grain (physical maturity), and setting sun (ageing). This qualitative research uses textual analysis by deeply reading to describe the heroes’ deaths in the plays. The conclusion was that the hero's death is simply a Shakespearean device for revealing the truth about anything. The message of peace is Romeo and Juliet's death as a vehicle for unifying two opposing families, as in Romeo and Juliet's tragedies between Capulet and Montague. It explains why there should be death when peace can be easily achieved. Furthermore, the revelation of truth through death confirms Desdemona's loyalty to Othello.
Correlation between Grammatical and Pragmatic Competences among Indonesian University EFL Learners
Authors: Adam Sutisno , Sailuddin Sartika Putri
Published: October 2023

Language competence not only refers to the underlying knowledge of the linguistic aspects of the language system under study, such as grammar and lexis, but also an understanding of the extra-linguistic features of a given communicative scenario, all of which contribute to meaning and the interpretation of meaning, This study aims to: (1) to determine whether there is a correlation between EFL Indonesian university students’ grammatical competence and their pragmatic competence, and (2) to investigate the influence of students’ grammatical competence towards their pragmatic competence. The data collected are from year 2 English students by using grammatical and pragmatic tests for students to answer. Their answers were analyzed quantitatively to obtain the mean score and further will be compared. The results show that: 1) students perform low on both aspects (m1=8.78, and m2=10.46, 2) there is a moderate positive correlation between the two sections (r=.54, p=0.01), and 3) students’ grammatical knowledge contributes on their pragmatic knowledge on medium level (t(65)=-.36, p=0.01). The average level of achievement that students could attain on grammar shows that it is still a challenging aspect in FL learning despite they have received 4 compulsory grammar subjects. This challenge should be taken into concern as the result of this study also shows that grammatical competence could affect learners’ initial competence on pragmatic as week. Therefore, there is a need of improvement on EFL teaching methods especially for grammatical subjects due to very low achievement on this central skill which will contribute to the other skills.
Enhancing Students’ Listening Skill by Spotify Application
Authors: Suwarni Andi , Sartika Dewi , Ika Andi
Published: October 2023

Listening cannot be separated from all activities, but in reality most of the teacher does not pay attention the student's ability to listen and that can affect students' ability in English especially when they want to talk to other people but don’t understand what is being said otherwise because they lack in listening. In the learning process, students may face difficulties one of them is difficulty in conveying speech. Many people say that listening is difficult, due to lack of focus or failure to focus. Therefore, practice concentration by listening more. The objective of the study is to find out spotify podcast application able to enhance the students’ listening skill. The writer apply pre-experimental method with one group pre-test and post-test design, and collected the data based on the test. The research findings showed that the students’ had poor score in pretest. After treatment, their listening ability in identify of listening comprehension increase significantly. The result of the research were the mean score obtained by the students’ through pre-test was 41.6 and post–test was 72.5 with the t-test value orientation is greater than t-table (16.8>2.06). Listening through Spotify podcast in term of identify the listening comprehension 74,2% The result of calculating t-test of the indicators in the students’ t-test listening ability in listening through Spotify podcast application was greater than t-table 24.1>2.06. It can be concluded that spotify podcast application can enhance the students’ ability in listening skill.
Don Kerubin Šegvić i pitanje sv. Dujma
Authors: Dukić Josip , Dukić Bernard
Published: October 2023

Pitanje sv. Dujma i apostoliciteta splitske Crkve, tj. njene izravne veze s apostolima, bilo je tijekom povijest u središtu istraživanja brojnih istraživača i još uvijek je vrlo aktualno. U znanstvenoj javnosti nedovoljno je poznato da je splitski svećenik don Kerubin Šegvić (Split, 23. II. 1867.  Zagreb, nakon 29. VI. 1945.) bio uključen u znanstvenu raspravu. U tom kontekstu nije nevažna činjenica da su don Kerubina komunističke vlasti u Zagrebu 29. lipnja 1945. osudile na smrt i potom likvidirale, što je njegov život i rad pretvorilo u tabu temu sve do početka demokratskih promjena u Hrvatskoj. Don Kerubin se uključio u raspravu početkom ožujka 1901., kada je u Splitu tiskana njegova znanstvena studiju “Storia e leggenda di S. Domnione o Doimo vescovo e martire di Salona e delle sue reliquie. Saggio storico-critico”. Šegvić se u studiji bavi pitanjem datuma Dujmove smrti, mjesta na kojem se čuvaju njegove kosti i štovanjem Dujma tijekom povijesti. Raspačavanje Šegvićeve studije zabranila je 9. ožujka 1901. rimska Kongregacija obredâ po preporuci splitskog biskupa Filipa Frane Nakića (1889. - 1910.). Kada je kancelar biskupa Nakića don Leopold Ivanišević 29. ožujka 1901. preuzeo od don Frane Bulića zaplijenjene primjerke don Kerubinove studije, don Frane je na svakom od četiri paketa napisao “Resurrecturis”, u nadi da će jednog dana te studije “uskrsnuti”. Što je u Šegvićevoj knjizi bilo sporno crkvenoj vlasti i koja je njezina znanstvena vrijednost, nastojat ćemo razjasniti u ovom članku.
Sadržaji povijestne i kulturne baštine u djelu don Mile Vidovića
Authors: Tomasović Marinko
Published: October 2023

Kritički se razmatra zastupljenost baštinske tematike u pisanom djelu don Mile Vidovića, ponajviše sadržane u reprezentativnim izdanjima. Vrednuje se kao vid populariziranja ponajprije donjoneretvanske umjetničke i arheološke topografije kao poticaja za njeno istraživanje. Naznačava se vrijednost i koristnost Vidovićevog priloga kulturnoj baštini, osobito kada se iznosi u izgledu brojnih i manje poznatih podataka. Novija terenska saznanja o lokalitetima, opisi crkava i uvid u njihov inventar, kao i informacije iz povijestnih vrela, tim putem upravo i podcrtavaju veliko značenje predočene materijalne kulturne baštine i povijestnog sadržaja.
Prevalence and Antimicrobial Susceptibility Pattern of Staphylococcus species causing Urinary Tract Infections in Women of Reproductive Age: 5 Years Retrospective Study
Authors: IBNOUF Sondos A. A. , GÜLBAY Sait Ramazan , DOGAN Metin
Published: October 2023

Background/Aim: Infections of the urinary tract are amongst the most prevalent infections in women, females at child-bearing age have a higher predisposition to urinary tract infections. Approximately 13% of health-care-associated urinary tract infections occur due to Coagulase Negative Staphylococci (CNS); this species’ resistance rate is alarming. The study aims to describe urinary tract infections of women of reproductive age through 5 years of results, emphasizing Staphylococcus species as an etiological agent and their antimicrobial susceptibility patterns.

Material and Methods: In the study, 4562 urine samples sent between November 2017 and November 2022 were retrospectively analyzed. Routine culture methods were used to isolate bacteria from urine specimens. According to the European Committee on Antimicrobial Susceptibility Testing (version 8.0-12.0) recommendations, an antimicrobial susceptibility test was performed using the disc diffusion technique. Obtained data analysis was achieved by Statistical Package for Social Sciences (SPSS 20.0), Categorical variables were presented as frequency and percentage however continuous variable was described as mean ± Standard deviation (SD), and binary logistic regression test was done to determine the association with statistical significance of (p
Detection of Fault from Acoustic Signals in Automobile Engines using Deep Learning Techniques
Authors: ERDOĞAN Fatih Alperen , KÜÇÜKMANİSA Ayhan , KİLİMCİ Zeynep Hilal
Published: October 2023

Detecting faults in automobile engines from sound signals is a challenging task in the production phase of automobiles. That is why it attracts engineers and researchers to handle this issue thereby applying various solutions. In this work, we propose a deep learning-based fault detection mechanism in automobile engines from different sound resources. In the dataset collection phase, various vehicle breakdown sounds are gathered from social media environments by constructing our own customized crawler. Moreover, noise addition is applied to increase the amount of data. Subsequently, raw audio files are processed at the feature extraction step employing mel-frequency cepstral coefficients. To detect the vehicle breakdown sounds, 1-D and 2-D convolutional neural networks, long short-term memory networks, artificial neural networks, and support vector machines are modeled. Experiment results show that the usage of a 1-D convolutional neural network is transcendent with 99% accuracy compared to the other techniques, especially, state-of-the-art studies are considered.
Aplicações clínicas dos cimentos biocerâmicos, vantagens e desvantagens do seu uso em tratamentos endodônticos: revisão de literatura
Authors: Lage Carielen Alves , Farias Jessica Pinheiro , Gama Rodrigo Nogueira , Lopes Luana Pontes Barros
Published: October 2023

Objetivo: avaliar as vantagens e desvantagens do uso de cimentos biocerâmicos utilizados em tratamentos endodônticos. Metodologia: desenvolveu-se uma revisão bibliográfica analítica de literatura entre janeiro de 2022 a janeiro de 2023 na base de dados eletrônicas PubMed/MedLine, utilizando as palavras-chave indexadas nos descritores em ciências da saúde da Medical SubjectHeadings: “biocerâmica”, “endodontia”, “vantagem” e “desvantagem”. Resultados: A partir da busca inicial utilizando os descritores booleanos se obteve um total de 29.741 artigos. Posteriormente, após a seleção pelo título, leitura do abstract e da metodologia e a leitura completa dos artigos pré-selecionados foram incluídos 11 artigos para a elaboração deste trabalho. Conclusão: embora já se tenha consenso na literatura quanto as propriedades bioativas e biocompatíveis dos cimentos biocerâmicos endodônticos estudos atuais vão de embate quanto sua propriedade seladora, que embora seja superior aos cimentos a base de resina epóxica, ainda não estão imunes a infiltração marginal.
Projeto pequenos gestos, grandes sorrisos: palestras promovendo saúde bucal na clínica odontológica da UEM e comunidade externa
Authors: De Oliveira Suelen Regina Bueno , Bornelli Isabela Larissa da Costa , Pereira Geovana Leonel , Araujo Maria Clara Barucci , Dos Santos Giselma Leite , Zilioli Thiago Alexandre , Da Silva Mariliani Chicarelli , Goya Suzana
Published: October 2023

O projeto "Pequenos Gestos, Grandes Sorrisos" do Departamento de Odontologia (DOD) da Universidade Estadual de Maringá (UEM) tem o intuito de promover melhorias às condições de saúde bucal dos pacientes de Maringá e região, por meio de ações coletivas que visam a orientação da população quanto à higiene bucal e possíveis doenças que acometem a cavidade bucal. Em 2018, o projeto esteve atuando externamente na comunidade, a convite de algumas organizações e eventos, orientando por meio de palestras, como cuidar da saúde bucal e na Clínica Odontológica da UEM, oferecendo palestras aos pacientes antes de seus atendimentos na sala de espera da clínica. As apresentações possuíam temas diversificados sobre saúde bucal e tinham por objetivo esclarecer dúvidas frequentes e integrar a relação dos participantes do projeto com a população, assim foram alcançados bons resultados. O projeto continua buscando expandir as ações em promoção da saúde bucal para toda a comunidade externa com o intuito de auxiliar na disseminação dos conhecimentos sobre a manutenção e melhora da saúde.
Identificação de questões relativas à saúde mental e ao uso de medicamentos na pandemia de Covid-19 em uma Universidade Pública da Baixada Fluminense
Authors: Costa Luana Martins de Souza , Oliveira Ana Paula Moreira , De Oliveira Janaína Pereira , Da Cruz Larrysa de Morais Alves , Rodrigues Matheus de Lima , Afonso Jéssica Guimarães Martins , De Aguiar Junior Valdinei Santos , Dos Santos Jaqueline Rocha Borges
Published: October 2023

No final do ano de 2019 emergiu a COVID-19, doença ocasionada pelo novo coronavírus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Para conter o avanço das infecções, medidas como o isolamento social foram adotadas. Durante a pandemia, muitas incertezas assombraram a sociedade como um todo, contribuindo para a piora de sintomas relativos à saúde mental. O impacto da pandemia também afetou a saúde mental da comunidade acadêmica, que vivenciou a transição e a adaptação das atividades presenciais para o modelo remoto. Esse trabalho teve como objetivos (1) identificar o perfil de saúde mental da comunidade acadêmica de uma Universidade Pública na Baixada Fluminense durante a pandemia de COVID-19, (2) identificar os sintomas relatados pelos indivíduos entrevistados e suas correlações com diagnósticos de transtornos mentais (3) avaliar o uso de medicamentos no período de isolamento social. Participaram da pesquisa 264 indivíduos e a coleta de dados foi realizada via formulário on-line na plataforma Google Formulários. Dentre os participantes 71,2% (n = 188) foram representados pelo sexo feminino. Com relação ao diagnóstico em saúde mental, a ansiedade teve o maior percentual de respostas, 35,2% (n = 88), seguida pela depressão 19,6% (n = 49). Os sintomas mais frequentes apresentados pelos participantes (n = 884) foram o desânimo persistente representado por 18,4% (n = 163), dificuldade de concentração representado por 17,3 % (n = 153) e insônia representada por 16,9% (n = 150) das respostas. A respeito do uso de medicamentos, os ansiolíticos e os antidepressivos foram os mais utilizados pelos participantes. A partir dos resultados obtidos, pode-se concluir um impacto negativo da pandemia de COVID-19 sobre a saúde mental da comunidade acadêmica relatada neste estudo, sugerindo a necessidade de Políticas Institucionais aplicadas à saúde mental.
Fibrilação Atrial - aspectos epidemiológicos, fisiopatológicos e manejo terapêutico
Authors: Santos Kennedy de Oliveira , E Borges Larissa Oliveira , Mourão Marcos Fernandes , Guazzelli Flávia Rech , Viana Samuel Sousa
Published: October 2023

A fibrilação atrial (FA) é a arritmia cardíaca mais prevalente em todo o mundo, afetando aproximadamente 33 milhões de pessoas. Sua incidência aumenta significativamente com a idade, atingindo uma taxa de 10-12% em indivíduos com 80 anos ou mais. Este artigo científico aborda os avanços no entendimento e tratamento da FA ao longo das últimas décadas. A FA é associada a complicações graves, incluindo insuficiência cardíaca, acidente vascular cerebral e, em casos extremos, morte. Fatores de risco para seu desenvolvimento incluem hipertensão arterial, obesidade, diabetes mellitus e predisposições genéticas. O estresse oxidativo e a inflamação são considerados contribuintes para o remodelamento atrial, que facilita o surgimento e a persistência da arritmia. Outrossim, os sintomas da doença podem variar, sendo algumas pessoas assintomáticas, enquanto outras experimentam palpitações, fadiga e dispneia. O diagnóstico é confirmado por meio de um eletrocardiograma (ECG), com o exame físico também revelando um pulso irregular e taquicardia. É importante notar que as mulheres tendem a relatar sintomas mais graves e uma pior qualidade de vida em comparação aos homens. Outrossim, no que tange ao tratamento, o manejo terapêutico da FA é multifatorial e inclui estratégias para controlar a frequência cardíaca, controlar o ritmo e prevenir o tromboembolismo arterial. A terapia de controle da frequência é realizada com medicamentos como betabloqueadores e bloqueadores dos canais de cálcio, dependendo das condições do paciente. Os digitálicos, como a digoxina, também são uma opção em casos refratários. Ademais, o tratamento cirúrgico envolve a ablação por cateter de radiofrequência ou a ablação por criobalão, consideradas terapias definitivas para modificar o mecanismo da FA.
Análise das internações por condições sensíveis à atenção primária (ICSAP) após o encerramento do programa mais médicos (PMM) na mesorregião do Vale do Jequitinhonha no ano de 2019
Authors: Viguini Julia Avancini , Cordeiro Thiago Oliveira , Miranda Hugo Araújo , Caetano Ramon Barbosa , Cordeiro Renan de Oliveira
Published: October 2023

Introdução: A criação do Programa Mais Médicos visou minimizar as disparidades da precariedade de médicos nas regiões mais remotas e desfavorecidas, como o Vale do Jequitinhonha em Minas Gerais. Foram realizadas análises retrospectivas que avaliam a mudança quantitativa das Internações por condições sensíveis à atenção primária (ICSAPs) no período de vigência do PMM, com objetivo de analisar o impacto do programa na rede de saúde do Vale do Jequitinhonha. Metodologia: Estudo ecológico com dados secundários referentes ao período de 2010 a 2020, sobre a região do Vale do Jequitinhonha-MG oriundos do Sistema de Informações Hospitalares (SIH-SUS).  Foi feita análise estatística com o propósito de avaliar a existência de associações significativas entre as ICSAP e o encerramento do PMM. Para isso, foram comparados o número de internações e óbitos por CSAP com a média da quantidade total de médicos e, posteriormente, com médicos da atenção básica no período analisado. Essas variáveis foram comparadas através da Correlação Linear de Pearson e por coeficiente de dispersão linear.Resultado: Obteve-se uma correlação linear negativa do número de internações por CSAPs tanto quando comparada aos médicos da ESF quanto ao número total. Entretanto, somente quando analisada em relação à quantidade total de médicos apresentou uma magnitude de correlação muito forte (R= -0,91), na qual o número total de médicos foi capaz de influenciar em, aproximadamente, 82% (R²) nas ICSAPs no Vale do Jequitinhonha. Essa correlação foi comprovada estatisticamente por meio da aplicação do Teste T de Student, no qual o T crítico para um nível de significância adotado de 0,05 e g.l. (graus de liberdade) = 9 obtido foi de 2,262, enquanto T calculado para o valor de R  foi -6,39, deduzindo-se assim que os resultados encontrados possuem relevância estatística. Conclusão: Foi possível verificar uma diminuição gradual nas internações com relação estatística significativa ao aumento no número de médicos, principalmente nas Equipes de Saúde da Família. O impacto do Programa Mais Médicos levanta a necessidade de novos estudos para avaliar seus efeitos. Os resultados também destacam as iniquidades em saúde e contribuem para o debate sobre o tema.