bluuebunny/crossref_metadata_2025 huggingface dataset:
Calculation Method of Interface Contact Thermal Resistance between Rock and Lining in High Rock Temperature Tunnels Considering the Lithology
Authors: Cui Guangyao , He Ziyang , Wang Daoyuan
Published: August 2024

The disasters caused by the high rock temperature are increasingly prominent. To accurately assess the temperature at the rock-lining interface in high rock temperature tunnels, the rock thermal conductivity evaluation coefficient was introduced to propose a method for calculating interface contact thermal resistance that accounts for the influence of the surrounding rock lithology. This method, based on a disc model, offers precise insights into the thermal resistance between the surrounding rock and the tunnel lining. To validate the efficacy of this method, initial numerical simulations and subsequently performed laboratory experiments across various rock-concrete interfaces were conducted. Laboratory experiments reveal that the interface contact thermal resistance between rock and concrete specimens tends to decrease as temperatures rise from 20°C to 80°C. Moreover, a substantial increase in interfacial contact thermal resistance was observed when dealing with higher-grade surrounding rock (indicating lower quality), reaching up to 111.24 %. The maximum relative error observed in the results of the calculation method is 8.64 %, well within the acceptable range of 15 %, confirming its reliability and practicality for engineering applications. These research findings can serve as a valuable reference for designing support structures in high-temperature rock tunnels and advancing disaster prevention and mitigation technologies.
Brincar no hospital
Authors: Aparecida Vendramini-Zanella Daniela , Coelho Liberali Fernanda
Published: August 2024

Este trabalho discute a atividade criativa em contextos de formação de alunos-educadores para atuarem em situações diversas. O estudo se fundamenta na Teoria da Atividade Sócio-Histórico-Cultural (Leontiev, 1977; Vygotsky, 1930, 1934), que compreende que na e pela atividade o homem realiza o movimento transformador de si e da natureza humana. Para o estudo, é analisado um excerto destacado do corpus de pesquisa de doutoramento de Vendramini-Zanella (em andamento). O artigo assume, como metodologia, a pesquisa crítica de colaboração (Magalhães, 2009), e discute o projeto de extensão Tempo de Aprender, da UNISO, vinculado ao Projeto Aprender Brincando, da PUC-SP. O evento analisado acontece no corredor de um hospital infantil como a proposta de possibilitar que, brincando, as crianças transcendam suas possibilidades imediatas. A análise focaliza aspectos enunciativo-discursivo-linguísticos da performance desenvolvida pelas crianças, permitindo constatar que o aluno-educador e as crianças produziram criativamente, mesmo com todas as limitações que o contexto apresentava.
Student-Centered Debates to Promote Active Learning in Biology
Authors: Liu Xingyou , Yang Nan , Zhou Wenhao , Shen Jie
Published: August 2024

The post-00s college students are a group of “internet natives” with distinctive personality and innovative spirit. It is important to explore how to motivate them to actively learn new knowledge. Debate, as a means of learning and communication, can enhance participants’ critical thinking skills, boost oral skills, and promote their learning of relevant knowledge. Here, we use the model of classroom debate in a general education biology course to debate scientific controversies. This increases students’ enthusiasm for independent learning of relevant knowledge and promotes effective independent inquiry and learning.
Using Children’s Literature to Engage Students in Argumentation About Infectious Diseases Through Role-Play
Authors: Namdar Ayşegül Oğuz , Namdar Bahadir , Ay Betül Büşra
Published: August 2024

Health education is critical for preventing the spread of infectious diseases and ensuring societal well-being. Children, on the other hand, are rarely actively involved in infectious disease education. Children’s literature promotes reasoning and engages students in argumentation and decision-making. Given the importance of active student participation in infectious disease education, we recommend using children’s literature to engage school students in role-playing argumentation. This approach not only bridges the gap in student engagement but also promotes argumentation in order to make informed decisions for both individual and public health.
Introduction to the Special Issue on Under Communism’s Shadow
Authors: Blackburn Matthew , Klimenko Ekaterina V.
Published: August 2024

Perhaps no topic could be more crucial to the concept of “post-communism” than how the Soviet past is commemorated, challenged, or forgotten. The study of historical memory is often correctly tied to identity politics and nation-building. While the usable past framework is broadly applicable to all modern states, in the Russian case a degree of alarmism and negativity surrounds interpretations of how the country has managed its communist past, particularly its violent parts. A significant element to this is a teleological view of progress and the salience of the transition paradigm. In memory studies, this is manifested in the dominance of the cosmopolitan memory mode as the correct way the violent past should be commemorated. The introduction reviews the existing literature on Russia’s memory politics and highlights three limitations: (1) overemphasis on the political center and the failure to capture the diversity of regions, (2) too much focus on the supply side of memory politics, and (3) one-sided presentations of the role the Great Patriotic War plays in Russian memory politics. The introduction reviews how the special issue contributions address these limitations in the literature and shows how, taken together, they offer ideas for new research on memory studies. A case is made for how this new research agenda can better understand memory processes and how they relate to broader ideological, cultural, social, and political change in Russia.
Book Review of Stephen Kinzer's "The True Flag: Theodore Roosevelt, Mark Twain, and the Birth of American Empire"
Authors: Caillot Alexandre
Published: August 2024

Book Review of Stephen Kinzer's "The True Flag: Theodore Roosevelt, Mark Twain, and the Birth of American Empire"
CENFAD Colloquium Schedule: Spring 2018
Authors: Perinovic Eric
Published: August 2024

CENFAD Colloquium Schedule: Spring 2018
Note from the Non-Resident Fellow
Authors: Moore Erik
Published: August 2024

In this brief piece, CENFAD's Non-Resident Fellow for the 2018-2019 academic year introdurces himself and gives a brief synopsis of his academic history and current research.
Book Review: Implacable Foes: War in the Pacific, 1944-1945
Authors: Kinney Brandon
Published: August 2024

Brandon Kinney, a graduate student at Temple University, reviews Marc Gallicchio's book Implacable Foes: War in the Pacific, 1944-1945.
Book Review: Losing Hearts and Minds: American-Iranian Relations and International Education During the Cold War.
Authors: Shoup Jonathan
Published: August 2024

Jonathan Shoup, a graduate student at Temple University, reviews Matt Shannon's book, Losing Hearts and Minds: American-Iranian Relations and International Education During the Cold War.
News from the Director
Authors: Fischer Michael
Published: August 2024

News from Director Alan McPherson
Review of The Girl Next Door
Authors: Fischer Michael , Natalo-Lifton Ariel
Published: August 2024

Review of Kara Dixon Vuic's The Girl Next Door by Ariel Natalo-Lifton.
Review of Jimmy Carter in Africa
Authors: Fischer Michael , Dennison Graydon
Published: August 2024

Review of Nancy Mitchell's Jimmy Carter in Africa by Graydon Dennison
Note from the Davis Fellow
Authors: VanSise Casey
Published: August 2024

Note from the 2021-22 Thomas J. Davis Fellow, Casey VanSise
Interview with Dr. Benjamin Talton
Authors: VanSise Casey
Published: August 2024

CENFAD community interview with Dr. Benjamin Talton, Professor of History at Temple University and CENFAD faculty member, concerning his book In This Land of Plenty: Mickey Leland and Africa in American Politics (University of Pennsylvania Press, 2019)
Optimización del régimen de dosificación de antibióticos a través de la integración farmacocinética/farmacodinámica: una revisión
Authors: Alexsandra Felix Larissa , Monte Egito Beatriz , Suárez Gonzalo , Ferrante Marcos
Published: August 2024

The indiscriminate use of antimicrobials led to the emergence of antimicrobial resistance (AMR), so the rational use of these medications becomes extremely necessary. Thus, an alternative is the use of pharmacokinetic/pharmacodynamic (PK/PD) integration, a tool used in human and veterinary medicine, to determine dosing regimen optimization. Optimizing the dosage regimen makes it possible to establish therapies with greater precision and probability of clinical success, in addition to minimizing toxicity and the spread of antimicrobial resistance. PK/PD integration studies are included in the European Medicines Agency (EMA) guidelines for evaluating medical products; however, this tool needs to be more widespread. Additionally, in 2015, the World Health Organization (WHO) established optimizing antimicrobial doses as one of the five critical points to help reduce the spread of AMR, so PK/PD integration can be used for this purpose. Therefore, this review aimed to elucidate the aspects of PK/PD integration in the selection and optimization of dosing regimens to increase awareness of their development and use by veterinary practitioners.
Reconstrucción quirúrgica de una hernia abdominal traumática con avulsión púbica en un canino
Authors: Chipayo G. Ysaac , Lozada P. Patricia , Bocanegra D. William
Published: August 2024

The case of a 5-year-old mixed-breed female canine who was brought to consultation after having suffered a car accident is reported. The animal had a large bulge in the caudal abdominal region. The physical examination showed that the mass was the product of a large eventration (intestinal loops and bladder). During the thoracic radiological examination, a slight pneumothorax was observed in the right hemithorax and partial collapse of the lung lobes on the left side, while the abdominal ultrasound ruled out further visceral involvement and confirmed the absence of a hernial sac. Once stabilization was achieved, the patient underwent an exploratory laparotomy where severe avulsion of the internal and external oblique, transverse and rectus abdominis muscles was confirmed at the insertion site to the cranial edge of the pubis. Surgical reconstruction of the abdominal wall at the pre-pubic level was carried out, through direct tissue apposition to correct such defects. One month after the surgical treatment, the patient's stability was confirmed.
Selección de cuyes futuros progenitores mediante un índice de selección que incluye rasgos productivos y morfológicos
Authors: Mantilla José , Idrogo Itamar , Mantilla Joe , Mendoza Pablo , Paredes Manuel
Published: August 2024

El estudio tuvo como objetivo identificar y seleccionar cuyes machos genéticamente superiores a través de rasgos productivos y morfológicos. Se construyó un índice genético a fin de determinar el Valor Probable de Cría (PVB) para características como incremento de peso (IPT), longitud corporal (LC), perímetro torácico (PT) y conversión alimenticia (CA). Cuarenta cuyes destetados fueron alojados en jaulas individuales de acuerdo con un diseño completamente aleatorio, distribuidos en dos tratamientos, cuyes Valle Cajamarca y cuyes Valle Condebamba. Cada tratamiento con 20 repeticiones. No se encontraron diferencias significativas (p>0.05) en los indicadores IPT, LC y PT; sin embargo, los cuyes Valle Condebamba fueron más eficientes en CArespecto a los Valle Cajamarca (p<0.05). Los valores de PVB parciales del 50% superior (Los 10 mejores cuyes de cada grupo) para cada carácter fue muy variable entre ambos ecotipos. El mejor valor de Índice de selección en los cuyes Valle Cajamarca fue de 1124.82 y en los cuyes Valle Condebamba, de 1158.74., donde los cuyes Valle Condebamba aportaron seis futuros reproductores y la población Valle Cajamarca aportaron con cuatro. Se concluye que los indicadores de crecimiento y el índice de selección permiten determinar los mejores cuyes machos como futuros reproductores por mérito genético a partir de dos ecotipos.
Efusión pleural en cachorro Labrador Retriever. Reporte de caso
Authors: Vanegas-Alonso B. , Gómez-Parra F. , Jaramillo-Chaustre X.
Published: August 2024

The therapeutic approach of a Labrador Retriever canine patient who arrives at the clinic with respiratory difficulty, orthopneic position and abdominal pain is described. Paraclinical tests are performed such as a hemo-leucogram, finding a decrease in the red line and a marked leucocytosis. In the radiographic projections, an increase in the density of the right hemithorax is seen and the presence of free fluid is confirmed by ultrasonography in the intercostal window. A thoracentesis is performed to determine the type of fluid and its subsequent evacuation from the cavity.
Analysis of the relationship between field size and change in radiation dose to patient and staff based on radiographic technique in fluoroscopy and radiography
Authors: Ferreira Karin Cristiane , Denyak Valeriy , Nunes Maria Cristina de Alencar , Nunes Gracielly Soares , Real Jessica Villa , Filipov Danielle
Published: August 2024

In discussions of radiological protection issues in fluoroscopy and radiography the radiation field size is usually mentioned in connection with unnecessary irradiation of the patient’s body parts that do not need to be imaged. However, excessive expansion of the field size leads also to some other effects: the excessive irradiation of assistants and visualized part of patient's body as well as the change in dose rate at the entrance of patient’s body by automatic brightness control. The aim of the present paper is to describe the results of an experimental study of the dependence of such effects on irradiation field size and primary X-ray spectrum. The measurements were carried out in conditions close to those of barium meal test. To simulate the patient body, 5 acrylic plates measuring 30 cm high x 30 cm long x 3 cm thick each were used, totalling 15 cm thick. The X2 RF Sensor (RAYSAFE) was used to measure the dose rate at the entrance and exit surface of the simulator and the specific model for measuring leakage and dispersion, the X2 Survey sensor (RAYSAFE), was used to measure the occupational dose rate. The occupational dose rate detector was located at the position that assistant usually maintains to support the patient's head and/or to administer the contrast. The results show that in radiographic mode dose rate at the exit of the patient’s body increases with the increase of field size. This increase reaches 85%. The increase of occupational dose rate in radiographic mode reaches 850% and is linearly proportional to the field area. In fluoroscopic mode, dose rate at the entrance of the patient’s body decreases proportionally to the increase of field side length because of the automatic brightness control. This effect reaches 25% with grid and 50% without grid.
The Influence of Hybridity on Salwa's Marriage in the novel Once in a Promised Land
Authors: Harly Nadhira , Maharani Gina Adisty
Published: August 2024

Hybridity, or the practice of blending cultures as diasporic individuals engage with locals in the country they moved to, can have a significant impact on an individual's life, such as on their relationship with their partner. This paper discusses the ways in which hybridity shapes the marriage life of the protagonist in the 2008 novel Once in a Promised Land by Laila Halaby. The study used a qualitative descriptive approach and Homi Bhabha's hybridity theories to analyze the novel's portrayal of the Jordanian married couples' conflicting pursuit of the American Dream, which gets complicated as more people get involved. The protagonist, Salwa, who has a hybrid identity that combines elements of their ancestral culture with the culture of the country in which they live, faces challenges with the hybridity of both her and her partner, Jassim, that affect their marriage. These challenges stem from the clash between Salwa's hybrid belief—the traditional Jordanian value of believing that someone can not be a complete woman until she bears a child that gets assimilated into her vision of a free-willed American woman—and Jassim's own vision of the American Dream as the traditional leading figure who gets control over their family, which does not believe that having a child is a form of freedom. During this conflict, a man named Jake comes into Salwa's life and gives her a false hope of a "free and welcoming home" in him, making her cheat on Jassim despite her own Eastern values echoing inside her mind. The novel highlights how hybridity can create tension and complexity within a marriage as Salwa and Jassim navigate their cultural differences while striving to live peacefully in their "home." The research deduced that Salwa and Jassim's clash, along with the involvement of Jake in their marriage, is due to their inability to adjust to the hybridity of their identities and also their lack of communication as a result of doing so.
Oliveira Viana, raça e autoritarismo brasileiro
Authors: Piza Duarte Evandro , Queiroz Marcos
Published: August 2024

O artigo investiga os fundamentos racistas do autoritarismo brasileiro por meio da análise da obra de Oliveira Viana. Primeiramente, desenvolve-se a ideia de “decantação branca da teoria social”, fenômeno pelo qual a branquidade separa e joga fora a crítica ao racismo de determinado autor, purificando seu pensamento. Em seguida, com base nos aportes de Clóvis Moura e Michel Foucault, são analisados como os argumentos de Viana a respeito do “tipo racial” local e do “povo” como objeto da ciência representam um momento de virada da ciência brasileira. Através do saber gerencial da população, tais concepções vinculam decisivamente “raça” e administração pública, constituindo a soberania como biopolítica e a arquitetura institucional do estado como gestão racial da vida e da morte. Conclui-se que o pensamento de Viana foi estratégico para lidar com os dilemas da branquidade brasileira diante dos impasses decorrentes do pós-abolição e das transformações políticas e econômicas globais do início do século XX.
‘Fuck’ and emoticons
Authors: Flesch Marie
Published: August 2024

This quantitative study investigates gender variation online by focusing on two ‘gendered’ linguistic variables: the swear word fuck, which has often been associated with men, and emoticons, which have been shown to be used more frequently by women than men. It is based on a nineteen-million-word gender-diverse corpus, which includes comments posted in English on the community website Reddit by 372 cisgender women, 372 cisgender men, 100 transgender women, 100 transgender men and 100 nonbinary individuals (all according to self-identification). The statistical analyses take both the gender and age of the Redditors into account. Results show that in most cases transgender men do not align with cisgender men; that transgender women mostly align with cisgender women in their use of fuck, but the former produce more emoticons than the latter, and that the use of the variables did not differ between nonbinary individuals assigned male versus female at birth.
‘Discourses of Global Queer Mobility and the Mediatization of Equality’ Joseph Comer (2022)
Authors: Marino Francesca
Published: August 2024

Discourses of Global Queer Mobility and the Mediatization of EqualityJoseph Comer (2022)Routledge, 252 pp.
‘Non-binary Gender Identities: The Language of Becoming’ Sebastian Cordoba (2023)
Authors: Nurfahmi Ardia Pramesti , Elian Yassar Muhammad Naufal , Wulandari Intan Kusuma
Published: August 2024

Non-binary Gender Identities: The Language of BecomingSebastian Cordoba (2023) Routledge, 180 pp.
Realcalinização do concreto sujeito à carbonatação: Revisão sistemática da literatura sobre os métodos de tratamento, eficácia e mecanismos da reação
Authors: Moraes Maryah Costa de , Cascudo Oswaldo , Oliveira Andrielli Morais de , Carasek Helena
Published: August 2024

RESUMO A realcalinização química (RAQ) e a realcalinização eletroquímica (RAE) são procedimentos utilizados como reparo de estruturas em concretos sujeitos à corrosão nas armaduras por ação da carbonatação. A premissa é elevar o pH da solução do poro do concreto, com o intuito de reestruturar o filme passivo das armaduras. A RAE é aplicada em estruturas a 40 anos e apresenta eficácia na reestruturação desta película. Já a RAQ é um método pouco abordado no meio cientifico. Este trabalho sintetiza informações, através de uma Revisão Sistemática da Literatura (RSL) com a técnica de snowballing, foram aderidos 24 trabalhos dos quais levantou-se os principais métodos de aplicação, soluções alcalinas e reações físico-químicas. Foi realizada uma análise comparativa entre a RAE e a RAQ, apesar de serem governados por mecanismos diferentes ambos foram eficazes em um período de tempo de 15 dias para reestabelecer o pH superior a 12, sendo também capazes de reestruturar o filme passivo das armaduras em sistemas com perda de massa decorrentes da corrosão abaixo de 0,25%. As principais lacunas da literatura são referentes aos mecanismos de reação da RAQ, alterações nas propriedades do concreto, duração de ambos os tratamentos e maior pré-disposição a reação álcali-agregado após o tratamento.
Gestão de transplantes no Brasil: análise temporal dos investimentos financeiros e procedimentos
Authors: Souza Mercy da Costa , Ferreira Júnior Marcos Antonio , Pompeo Carolina Mariano , Mota Felipe Machado , Cury Elenir Rose Jardim
Published: August 2024

RESUMO Objetivo: Analisar as ações gerenciais públicas dos investimentos financeiros e procedimentos de transplantes de órgãos, células e tecidos no Brasil. Método: Estudo ecológico misto (tempo e local), realizado com base em dados do Sistema de Informações Hospitalares do Sistema Único de Saúde do Departamento de Informática do SUS e do Sistema Nacional de Transplante, de 2001 a 2023. Foram realizadas análises de tendência temporal, estatística descritiva e inferencial. Resultados: Os transplantes de órgãos, células e tecidos encontram-se concentrados na região Sudeste do país, com aumento dos custos no local. As regiões Nordeste e Sul do Brasil apresentam a maior fila de espera, com uma tendência crescente (R2 = 0,96), associada a tendência decrescente do número de transplantes (R2 = 0,97). Conclusão: A diferença do total de transplantes e procedimentos realizados entre as regiões do Brasil representa a necessidade de organização e investimentos com estratégias voltadas para a capacitação de profissionais e conscientização da população.
Investimento Estrangeiro Direto da China no Brasil: um estudo de setores selecionados
Authors: Freitas Higor de , Borghi Roberto Alexandre Zanchetta
Published: August 2024

Resumo Após ter se tornado o principal parceiro comercial do Brasil em 2009, a China passou a exercer papel fundamental sobre a entrada de investimentos em setores estratégicos da economia brasileira. Durante os anos de 2005 a 2022, o IED acumulado chinês no país atingiu a marca de US$ 79 bilhões, com predominância em petróleo e gás (37%) e energia elétrica (33%). Diante desse quadro, o objetivo do artigo consistiu em analisar a intensificação dos investimentos da China no Brasil, tomando por base as estratégias mais amplas de internacionalização do capital chinês. O estudo identificou uma concentração maior em setores de energia, o que, por um lado, deriva não apenas da busca chinesa por tais recursos mundo afora, mas também de características do Brasil no período estudado, e que, por outro, implica em formas distintas de participação do capital chinês no país, seja via fusões e aquisições, como no setor elétrico, ou concessões de exploração, no caso de petróleo e gás.
Novo boom das commodities e a crescente participação chinesa na estrutura de comércio exterior do Brasil*
Authors: Leite Alexandre Cesar Cunha , Rodrigues Bernardo Salgado
Published: August 2024

Resumo As relações econômicas sino-brasileiras vêm gradativamente ganhando um perfil estratégico no século XXI. Desde 2009, a China se apresenta como o maior parceiro comercial do Brasil. No período de janeiro a novembro de 2023 (MDIC), essa relação atingiu o recorde de participação no fluxo comercial total entre os dois países. Este artigo tem como objetivo analisar a estrutura econômica dessa nova etapa de relações comerciais entre Brasil e China, estabelecendo como marco temporal o novo boom das commodities e o respectivo aumento da demanda chinesa observado no início da década de 2020. Através da análise primária das estatísticas de comércio exterior do Brasil e por meio de uma pesquisa de cunho exploratório, vislumbra-se um redirecionamento das empresas e capitais chineses para o setor de commodities brasileiro. Tal fato possibilita realizar uma avaliação das externalidades positivas e negativas para a estrutura produtiva nacional.
Analysis of participation restriction and high-frequency audiometry in adults and elderly people with mild hearing loss
Authors: Dias Lurdiana Guimarães , Alves Heloisa de Miranda Cantuaria , Castiquini Eliane Aparecida Techi , Paranhos Netto Marisa , Mondelli Maria Fernanda Capoani Garcia
Published: August 2024

ABSTRACT Purpose to compare the responses of adults and elderly people with mild hearing loss in the participation restriction inventory and relate the degree of restriction with hearing loss at high frequencies, as well as to evaluate whether there is a difference between the responses of men and women in relation to participation restrictions. Methods the sample of 38 participants was made up of adults and elderly people with an average of 67 years of age, of both sexes, enrolled in a hearing health service. High Frequency Audiometry was performed and the Hearing Handicap Inventory for Adults or Hearing Handicap Inventory for Elderly questionnaires were administered. The statistical study applied to the data was the Mann-Whitney test, oneway analysis of variance and Chi-Square. Results significant differences were found between the elderly and adult groups in relation to the degree of participation restriction, but no correlations were found between high frequency audiometry and the degree of participation restriction. It was also possible to observe that women have a greater degree of participation restriction than men. Conclusion adults have higher rates of perception of participation restrictions when compared to the elderly and there is a difference between the perception of handicap according to gender, but the results of the questionnaires are not related to hearing loss in high frequencies in this population.
Análise da restrição de participação e da audiometria de altas frequências em adultos e idosos com perda auditiva leve
Authors: Dias Lurdiana Guimarães , Alves Heloisa de Miranda Cantuaria , Castiquini Eliane Aparecida Techi , Paranhos Netto Marisa , Mondelli Maria Fernanda Capoani Garcia
Published: August 2024

RESUMO Objetivo comparar as respostas de adultos e idosos com perda auditiva de grau leve no inventário de restrição de participação e relacionar o grau de restrição com a perda auditiva em altas frequências, bem como avaliar se há diferença entre as respostas de homens e mulheres em relação à restrição de participação. Métodos a amostra foi composta por 38 adultos e idosos, com média de 67 anos de idade, de ambos os gêneros, matriculados em um serviço de saúde auditiva. Foi realizada audiometria de altas frequências e foram aplicados os questionários Hearing Handicap Inventory for Adults ou Hearing Handicap Inventory for Elderly. Os estudos estatísticos aplicados foram o teste de Mann-Whitney, análise de variância unidirecional e teste Qui-Quadrado. Resultados foram encontradas diferenças significativas entre os grupos de idosos e adultos em relação ao grau de restrição de participação, mas não foram encontradas correlações entre a audiometria de altas frequências e o grau de restrição de participação. Ainda, foi possível observar que as mulheres apresentaram maior grau de restrição de participação que os homens. Conclusão adultos apresentam maiores índices de percepção de restrição de participação quando comparados com idosos e há diferença entre a percepção do handicap conforme o gênero, porém, os resultados dos questionários não estão relacionados com a perda auditiva em altas frequências na população estudada.
The Body Atom and psychosomatics
Authors: Azis Violeta , Milcheva Alexandrina
Published: August 2024

ABSTRACT The authors of this article have created a unique technique based on their experience working with patients in both general hospital and private setting. The technique, called the Body Atom, is based on Moreno’s idea of the social atom and the theories developed by L’Institut de Psychosomatique Pierre Marty for understanding the origins and progression of psychosomatic diseases. The Body Atom was applied to hospitalized patients with cardiological diseases and patients with endometriosis in a private practice setting. Both groups responded positively to implementing the Body Atom, which helped them understand their personal experiences and relate them to their illnesses and body parts.
Factors associated with delayed initiation of breast cancer treatment at an oncology referral center in Juiz de Fora, Minas Gerais state, from 2010 to 2019: a cohort study
Authors: Silva Fernanda de Paula Ciribelli da , Souza Mirian Carvalho , Bertoni Neilane
Published: August 2024

ABSTRACT Objectives To analyze factors associated with delayed initiation of breast cancer treatment at an oncology referral center in Juiz de Fora, Minas Gerais state, between 2010 and 2019. Methods This was a cohort study using data from the Hospital-based Cancer Registry. The probability of not starting treatment within 60 days, in accordance with Brazilian law, was estimated using Kaplan-Meier, method and its association with the factors studied was assessed using the Cox model, presenting hazard ratios (HR) and respective 95% confidence intervals (95%CI). Results Among the 911 participants, the probability of delayed treatment initiation was 18.8% (95%CI 16.4;21.5). Those who underwent treatment at a health service other than the one where the cancer was diagnosed had a significantly higher risk (HR: 3.49; 95%CI 3.00;4.07). Conclusion Receiving a diagnosis and treatment at the same institution may help reduce waiting time to initiate cancer treatment.
Desigualdades raciais na vacinação infantil e nos obstáculos à vacinação no Brasil entre nascidos vivos em 2017 e 2018: análise de uma coorte retrospectiva dos dois primeiros anos de vida
Authors: Boing Antonio Fernando , Boing Alexandra Crispim , França Ana Paula , Moraes José Cássio de , Silva Adriana Ilha da , Ramos Jr. Alberto Novaes , França Ana Paula , Oliveira Andrea de Nazaré Marvão , Boing Antonio Fernando , Domingues Carla Magda Allan Santos , Oliveira Consuelo Silva de , Maciel Ethel Leonor Noia , Guibu Ione Aquemi , Mirabal Isabelle Ribeiro Barbosa , Barbosa Jaqueline Caracas , Lima Jaqueline Costa , Moraes José Cássio de , Luhm Karin Regina , Caetano Karlla Antonieta Amorim , Lima Luisa Helena de Oliveira , Antunes Maria Bernadete de Cerqueira , Teixeira Maria da Gloria , Teixeira Maria Denise de Castro , Borges Maria Fernanda de Sousa Oliveira , Queiroz Rejane Christine de Sousa , Gurgel Ricardo Queiroz , Barata Rita Barradas , Azevedo Roberta Nogueira Calandrini de , Oliveira Sandra Maria do Valle Leone de , Teles Sheila Araújo , Gama Silvana Granado Nogueira da , Mengue Sotero Serrate , Simões Taynãna César , Nascimento Valdir , Araújo Wildo Navegantes de
Published: August 2024

RESUMO Objetivo Descrever a completude vacinal em tempo oportuno nos primeiros 24 meses de vida no Brasil e os obstáculos para vacinação, testando-se associações com raça/cor da pele materna. Métodos Fez-se coleta de informações sobre os nascidos em 2017 e 2018, constantes no Inquérito Nacional de Cobertura Vacinal. Foram calculados prevalência e intervalos de confiança de 95% de obstáculos à vacinação e completude vacinal em tempo oportuno aos 5 meses, primeiro e segundo ano, segundo raça/cor da pele materna. Empregou-se regressão logística para análise de associações. Resultados Analisaram-se dados de 37.801 crianças. Do total, 7,2% (IC95% 6,3;8,2) dos responsáveis enfrentaram dificuldades para levar seus filhos para vacinação e 23,4% (IC95% 21,7;25,1) das crianças não foram vacinadas, mesmo sendo levadas. Essas proporções foram 75% (IC95% 1,25;2,45) e 97% (IC95% 1,57;2,48) mais elevadas, respectivamente, entre pretas; e 49,9% (IC95% 47,8;51,9) e 61,1% (IC95% 59,2;63,0) das crianças tiveram atraso em alguma vacina até os 5 meses e o primeiro ano, respectivamente. Tais valores foram maiores entre pardas/pretas. Conclusão Há desigualdades raciais nos obstáculos enfrentados e na vacinação no Brasil.
Tendência do risco epidemiológico da hanseníase no estado de Goiás entre 2010 e 2021
Authors: Barbosa Caio Cesar , Guimarães Rafael Alves , Vieira Nayara Figueiredo
Published: August 2024

RESUMO Objetivo Analisar a tendência do risco epidemiológico da hanseníase no estado de Goiás e macrorregiões de saúde de 2010 a 2021. Método Análise de série temporal do indicador composto do índice composto de risco epidemiológico de hanseníase em Goiás. Utilizaram-se casos do Sistema de Informação de Agravos de Notificação para cálculo dos indicadores isolados e o risco foi classificado em alto, médio, baixo e muito baixo. A tendência foi analisada pela regressão linear de Prais-Winsten e foram produzidos mapas de risco. Resultados Goiás apresentou alta endemicidade para hanseníase (24,8 casos/100 mil habitantes) e médio risco epidemiológico 2019 e 2021 (0,58). Observou-se tendência estacionária (variação percentual anual, 0,50; intervalo de confiança de 95%, -3,04; 4,16) para o risco da hanseníase em Goiás e macrorregiões Centro-Oeste e Centro-Sudeste. Conclusão Verifica-se a necessidade de ações para reduzir o risco epidemiológico da hanseníase, especialmente com tendência estacionária, e isso inclui medidas de rastreamento precoce de novos casos e educação em saúde.
EXPLORING IMPACTS OF USING POROUS MEDIA ON HEAT TRANSFER IN HELICAL COILS: A COMPREHENSIVE NUMERICAL STUDY
Authors: Bahrami Hamid-Reza , Mohseni Mahdi
Published: August 2024

The advantages of porous media in enhancing heat transfer have been well established. Similarly, the benefits of helical tubes in generating secondary flows, promoting flow mixing, and improving heat transfer are also recognized. However, previous studies have not thoroughly examined the combined effects of using porous media and helical tubes to enhance heat transfer. This study aims to demonstrate that careful selection of porous media can leverage both the heat transfer enhancements provided by porous structures and the secondary flow effects induced by helical tubes, thereby improving overall heat transfer performance. The key findings are that porous material significantly improves heat transfer, with the highest Nusselt number reaching around 450 in a straight tube filled with porous material at Da = 0.1 and Re = 2000-about 103 and 17 times higher than the Nusselt number in the straight and helical tubes without porous material, respectively. The rate of exergy destruction was calculated to determine the optimal operating point of the system. The peak values of the performance evaluation criterion (PEC) were 2 times greater in the helical tube filled with porous material compared to straight tubes filled with porous material, and 17 times greater compared to nonporous helical coils, indicating significant enhancement. The study also reveals that porous media with high permeability (Da ~ 0.1) can amplify heat transfer alongside the secondary flow in helical tubes, while low-permeability porous media (Da ~ 0.0001) diminish the impact of secondary flow, resulting in similar thermal performance between helical tubes and straight tubes filled with porous material. The main achievement of this work is demonstrating that porous media can be applied to amplify heat transfer in helical tubes under specific conditions, providing a viable method to enhance thermal efficiency and minimize exergy destruction.
Establishing automatic coating paths: empirical study for steel component production
Authors: Chen Jieh-Haur , Su Mu-Chun , Nguyen Thi Thu Ha , Lin Wei-Jen , Yu Tzuyang
Published: August 2024

The higher the complexity and size of H-shaped steel components, the more productivity challenges a coating factory encounters, particularly when catering to the intricate demands of customer-oriented industries. The aim of this research was to devise efficient coating paths for H-shaped steel components, replacing labour-intensive manual processes. A review of the existing literature revealed methodologies involving parameter adjustment, configuration recognition and optimisation of coating paths for H-shaped steel components. Using a comprehensive database of H-shaped steel components, an algorithm was developed to identify components accurately (>90% accuracy) and subsequently streamline the coating process. Through a comparative evaluation of 99 diverse scenarios of H-shaped steel coating, the results showed an average time reduction of 24.6% compared with manual coating methods. This finding bears significance given the industry’s challenges with a scarcity of skilled labour and elevated coating expenses, both of which hinder smooth business operations for practitioners.
Caracterización del campo de estudios sobre violencia de género y justicia penal en América Latina
Authors: Medina González Paula , Guala Natacha , Gutiérrez Valdés Moira
Published: August 2024

El objetivo de este trabajo fue realizar una caracterización de la investigación científica sobre la respuesta de la justicia penal a la violencia de género en América Latina. El método utilizado correspondió a una revisión sistemática utilizando el protocolo PRISMA 2020 (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). Se seleccionaron 306 publicaciones científicas que fueron categorizadas, sistematizadas y analizadas en relación a su objeto de investigación, los marcos teóricos, las estrategias metodológicas utilizadas y los hallazgos obtenidos. Los resultados indican que este es un campo de estudios de data reciente y acotado en relación con otras dimensiones que se han examinado sobre la violencia de género en América Latina. Asimismo, las investigaciones analizadas dan cuenta de un diagnóstico especialmente crítico de la justicia penal, evidenciando la distancia existente entre los textos legales y la aplicación práctica de la justicia, así como su falta de eficiencia y eficacia para responder adecuadamente a la violencia de género. En la discusión se señala la necesidad de profundizar los estudios sobre el tema, en especial, desde las aproximaciones empírico metodológicas, las que pueden iluminar las brechas, barreras y desafíos pendientes para que las reformas normativas en la materia avancen en pertinencia y en una aplicación efectiva y, por otra parte, para evidenciar los límites de la intervención penal y abrir nuevas alternativas de respuesta a la violencia de género, que prevengan su ocurrencia y protejan adecuadamente los derechos de niñas y mujeres.
The Wind Is Not Moved Air. Back To (Quasi) Things Themselves
Authors: Griffero Tonino
Published: August 2024

The wind is the topic of a desirable pathic aesthetics and neophenomenology of air. More specifically, it is a good example of an atmospheric ephemeral quasi-thing, because, as religions have always recognized, it blows where it wishes. It involves us on the affective and felt-bodily level as an atmospheric feeling poured out into pre-dimensional space: that is, as a very concrete experience, significantly both climatic and affective, physical and felt-bodily. Unlike full-fledged things, the wind is not edged, discrete, cohesive, or solid; it does not possess immanent and regular tendencies; it can appear in a partial form, without doing so through fragments and sides; it is (felt as) more immediate and intrusive than things, generating inhibiting or attracting motor suggestions; it dies down with the same inexplicable immediacy with which it rises; it does not have a threefold causality (cause-action-effect) but a twofold one (cause/action-effect). Given these quasi-thingly wind characteristics, the paper sketches a review of the main types of felt-bodily resonance, within a range whose two extremes are narrowness and vastness, triggered by windy atmospheres (for example sudden gust of wind, breeze, shallow wind, stormy wind and calm).
Freezing Adherent Cell Lines v2
Authors: Lopez Carolina
Published: August 2024

This protocol describes how to freeze Adherent cells. Examples of these cells are: A549 cells, LLCMK2 cells, and MDCK cells.
Transcription Factor Binding: Singleplex Assay for Function Measurements v1
Authors: Ross David
Published: August 2024

This protocol outlines an assay for measuring the function of plasmid variants in singleplex. The inputs include separate E. coli glycerol stocks for each of 3 variants, distributed according to the provided function plate map (see attachments). The protocol begins with several growths which convert the separate glycerol stocks into cultures that have reached stationary phase in a 96-well plate. The glycerol stocks are first grown overnight in separate tubes. The next morning, the optical density (OD) of each culture is measured, and then each culture is distributed into a 96-well growth plate. This plate is placed in a plate reader/incubator to grow to stationary phase (~12 hours) without antibiotics or additives (except those required for plasmid maintenance). After this point, the cultures are ready to act as an inputs for the next growth cycles where a 2-fold dilution series of the corresponding inducer is introduced. Throughout the subsequent growths, optical density (OD) and fluorescent measurements are recommended to be taken every 5 minutes and at the end of each growth plate's incubation. The growth cycles are all ~3 hours long, so that cells stay in mid-log phase. At the end of the last growth cycle, the cultures in the growth plate act as input for quantification using either a flow-cytometry or a plate reader. Note that unlike the related fitness assays, this assay does not use a selection antibiotic.
Isolated Brain Mitochondria Respiration protocol v1
Authors: Hecke Morais Livia , Stiles Linsey
Published: August 2024

Brain Mitochondria Respiration protocol. Assay developed by Dr. Linsey Stiles at the UCLA MetabolomicsCenter, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA
Protocol TE Display sequencing (TED-Seq) v1
Authors: not provided pol.vendrell , Leduque Basile , Quadrana Leandro
Published: August 2024

Background: Mobilization of transposable elements (TEs) can generate large effect mutations. However, because new TE insertions are challenging to detect and transposition is typically rare, the actual rate and landscape of new insertions remains unexplored for most TEs. Results: Here, we introduce a TE display sequencing approach that leverages target amplification of TE extremities to detect non-reference TE insertions with high sensitivity and specificity. By implementing this approach on serial dilutions of genomic DNA from A. thaliana lines carrying different repertoires of new TE insertions, we show that the method can detect TE insertions that are present at frequencies as low as 1:250 000 within a DNA sample. In addition, TE display sequencing can be multiplexed to simultaneously detect insertions for distinct TE families, including both retrotransposons and DNA transposons, increasing its versatility and cost-effectiveness to investigate complex “mobilomes”. Importantly, when combined with nanopore sequencing, this approach enables the identification of insertions using long-reads and achieves a turn around time from DNA extraction to insertion identification of less than 24h, significantly reducing the time-to-answer. Analysis of TE insertions in large populations of A. thaliana plants undergoing a transposition burst demonstrate the power of the multiplex TE display sequencing to assess the rates and allele frequencies of heritable insertions, enabling its implementation to study large-scale ‘evolve and resequence’ experiments. Furthermore, we show that ~6% of de novo TE insertions show recurrent allele frequency changes consistent with either positive or negative selection. Conclusions: TE display sequencing is an ultra-sensitive, specific, quick, and cost-effective approach to investigate the rate and landscape of new insertions for multiple TEs in large scale population experiments. We provide a step-by-step experimental protocol as well as ready-to-use bioinformatic pipelines, ensuring straightforward implementation of the method.
Image Capture and Neuropathological Quantification of post-mortem human brain tissue v1
Authors: Suteja Felicia , Li Hongyun , Fu YuHong , Halliday Glenda
Published: August 2024

This protocol details the fluorescent image analysis pipeline using QuPath to analyse pathological inclusions within human post-mortem brain tissue.
Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases v1
Authors: Ramesh Sriram , Rapp Samuel , Tapias Gomez Jorge , Truong Zia , Chung Dickson , Levine Benjamin , Tapias-Gomez Daniel
Published: August 2024

Knowledge of which organisms have publicly available reference sequences at known DNA barcoding loci is crucial for both metabarcoding studies and the design of new primers. In a metabarcoding study, taxa of interest can not be detected if there are no labeled reference sequences to compare to. Similarly, designing species-specific primers is only possible if there are enough reference sequences for both the target taxa and their phylogenetic relatives to represent the genetic diversity across individuals. The purpose of this is to tool allow scientists to automatically gather reference sequences from NCBI, BOLD and CRUX. It is important to note that this is just a in-depth guide on how to use the tool, for more details on the features and their importance please refer to our paper in: https://www.biorxiv.org/content/10.1101/2023.09.20.558722v3
Voltage sensor imaging in a population of dopaminergic axons in the mouse striatum v1
Authors: Duquenoy Lucille , O'Connor Bethan , J Cragg Stephanie
Published: August 2024

This protocol describes how to perform voltage sensor imaging from a population of striatal dopaminergic axons using high frame rates (600 Hz minimum) on coronal mouse brain slices. In particular, this protocol has been optimised for the use of ASAP5f voltage sensor (AAV9-EF1α-DIO-ASAP5-WPRE) from the Lin lab and changes in fluorescence are resulting from electrical stimulation.
Intact and clean nuclei isolation from wheat meristems v1
Authors: Faci Isabel , RW Jones Maximillian , Uauy Cristobal
Published: August 2024

This protocol describes how to perform nuclei isolation from wheat meristem tissues (spikes and carpels/ovaries), specifically from flash-frozen tissues. With this protocol, we obtain intact and clean nuclei for downstream applications.