bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the research competence of applicants enrolling into doctoral programs in healthcare professions: a cross-sectional study (Preprint)
Authors: Derbissalina Gulmira , Zemlyanskaya Natalya , Umbetzhanova Ayagoz , Kassym Laura , Alibekova Gulzhan , Koikov Vitaliy
Published: May 2024

BACKGROUND

Understanding the research competence of incoming doctoral students in healthcare is crucial for ensuring the quality and effectiveness of future healthcare research. By addressing gaps in research competency early in their academic careers, doctoral programs can better equip students to tackle the complex challenges facing the healthcare industry. The study investigates the research competency of incoming doctoral students in the healthcare field.

OBJECTIVE

To assess the level of research competence of applicants (residency and master's programs graduates) who plan to pursue doctoral studies in healthcare specialties.

METHODS

A cross-sectional study was conducted among 500 resident and master students and graduates who are willing to pursue Ph.D. study in the healthcare sector from 1st November 2023 till 16th February 2024. Prospective Ph.D. candidates represent all seven medical universities of Kazakhstan. Level of research competencies was assessed by the 31-item questionnaire "Research competence of postgraduate students" [1]. This questionnaire consists of three domains - "knowledge", "skills" and "attitudes". A multifactorial regression analysis was applied to ensure the reliability of the obtained results.

RESULTS

The participant’s average age is 27.8 years (SD ±4.3). Of these, 353 (70.6%) are women and 147 (29.4%) are men. Most of them (350 (70.0%)) are residents, 92 (18.4%) - master students of 1st and 2nd years.
Study results demonstrate that the main gaps in research competence in “knowledge” domain are the defining relevant theories of research and statistical methods understanding. In “skills” domain - lack of study planning skills, development of conceptual research model and identifying proper statistical method. In “attitude” domain - the respondents' greatest source of stress stems from the need to conduct research. The comparing domains between residents and master's students a statistically significant difference was found in the 'knowledge' domain (p<0.001) and the 'skills' domain (p<0.001). In assessing the overall mean value of research competency levels among candidates applying for admission to a Ph.D. program, it was found to be 85.9 points among master's students, corresponding to a high level, while among residents it was 80.3, corresponding to an average level of research competency.

CONCLUSIONS

While respondents demonstrate high and moderate levels of research competency in articulating objectives and relevance, further training is required in areas such as applying theories, selecting methodology, and conducting statistical analysis of data. The stress associated with research underscores the importance of providing participants with sufficient resources and support. These findings might inform the development of a pre-Ph.D. educational program in healthcare specialties.
Optimising the pharmacotherapy of vascular surgery patients at hospital admission and at discharge (PHAROS): study protocol for quasi-experimental clinical uncontrolled trial (Preprint)
Authors: Porubcova Slavka , Lajtmanova Kristina , Szmicsekova Kristina , Slezakova Veronika , Tomka Jan , Tesar Tomas
Published: May 2024

BACKGROUND

Patient safety is the absence of preventable harm to a patient during the process of providing health care and reduction of the risk of unnecessary harm associated with health care to an acceptable minimum. It is coming in the forefront of interest worldwide in healthcare delivery.

OBJECTIVE

The aims of this protocol are to assess the impact of pharmaceutical care in collaboration with physicians on the prevalence of drug-related problems at hospital admission and discharge in vascular surgery patients.

METHODS

The study is conducted in the Vascular Surgery Department at the National Institute of Cardiovascular Diseases in Bratislava, Slovakia during 1-year period, included adult patients with carotid artery disease or lower extremity artery disease, taking ≥3 medications. The estimated population for this clinical uncontrolled trial is approximately 100. Medication reconciliation and medication reviews will be performed by hospital pharmacists at both admission and discharge. Pharmacist-proposed interventions will be documented and communicated to the physician, patients will be educated about their medications upon discharge.

RESULTS

The key focus area of this project will be the identification of drug-related problems, their occurrence and type. As a part of further research, analysis will be performed to describe the degree of acceptance of the proposed changes in pharmacotherapy by physicians, groups of drugs based on the Anatomical Therapeutic Chemical classification system with the highest incidence of drug-related problems and identify patients at highest risk for drug-related problems taking in consideration their personal and health information.

CONCLUSIONS

This study should demonstrate that pharmacist-led interventions in collaboration with physicians could reducing the risks of pharmacotherapy and optimising medicines management and control systems for patient safety.

CLINICALTRIAL

ClinicalTrials.gov
Identifier: NCT04930302
Internet search data and mental health: promises and pitfalls (Preprint)
Authors: LOCH ALEXANDRE , Wolpert Miranda , Bilsland Lynsey , Netsi Elena , Brown Matthew , Williams Gwydion , Takhar Shuranjeet , Christofi Christopher , Kotov Roman
Published: May 2024

UNSTRUCTURED

Internet is now integral to everyday life, and users' online search data could be of strategic importance in mental healthcare. As shown by previous studies, it may provide valuable insights into individuals mental state, and can be of great value in early identification and in helping pathways to care. Internet search data can potentially provide real-time identification and alert mechanisms to timely interventions, for instance. In this viewpoint paper, we discuss the various problems related to the use of this data in research and in clinical practice such as privacy, integration with clinical information, and other technical challenges. We propose solutions to address these issues, and possible directions to follow.
Principal Component Analysis for Geochemical Data Analysis and Chemical Elements Associations of Prospective Kolumbe Area (Kema Terrain, Sikhote-Alin Folded Belt)
Authors: Shevyrev Sergei , Boriskina Natal'ya , Ivin Vitaliy
Published: May 2024

Native manifestations and deposits of precious metals of folded belts of surrounding of the North Asian and Sino-Korean cratons are of lesser resources and areas; that requires growth of research and technological potential for discoveries of the mineralizations. In Sikhote-Alin folded belt, which is typical example of boundary folded belts developed over a subduction zone, terranes of different age are described. Basements of these terranes are of accretion, island arc and turbidite origin, intruded by magmatic rocks and overlain by volcanic-sedimentary cover. Conducted researches consider area of island arc Kema terrane, which occupies large territories of the Strait of Tartary continental coast. Au-Ag deposits here are related to the origin and development of the active volcanic boundary. Genesis of the ore objects here is epithermal and related to intrusive and effusive complexes of Upper Cretaceous and Paleogene ages. Detailed field lithogeochemical surveys were held on a prospective Kolumbe site where Upper Jurassic–Lower Cretaceous siliceous and terrigenous rocks are intruded by Cretaceous granites of Tatibinski and Olginsky complexes. Research of the geochemical features was done using Principal Component Analysis, the effective method of dimensional reduction and data filtration. Implementation of that method in geochemical data analysis facilitates outlining of the associations of the elements by unifying them into principal components and discover their spacial distribution related to geological complexes of the research area. Determining of the number of principal components used explained variance covered by these components. Derived maps of the spatial distribution of principal components that include elements associations allowed to determine the locations of the local geochemical extrema. Grouping of elements into principal components made it possible to assume the staging in ore deposition in a prospective Kolumbe site. Conducted studies could invigorate further more detailed researches of the minerageny of the considered area.
The Impact of College Students' Career Decision Self-Efficacy on Career Adaptation from the Perspective of High-Quality Employment: The Mediating Role of Career Preparation Behavior
Authors: Du Baiyan , Sheng Xiaojing , Ye Qun , Lai Yuege
Published: May 2024

This study primarily analyzes the impact of career decision self-efficacy and career preparation behavior on career adaptation, discussing the mediating role of career preparation behavior among 522 college students. The results show significant positive correlations among career decision self-efficacy, career preparation behavior, and career adaptation. Career decision self-efficacy significantly positively influences career preparation behavior, with the sub-factors of influence in descending order being problem-solving, future planning, and goal-setting. Self-evaluation and career information do not have a significant impact on career decision self-efficacy. Career decision self-efficacy also has a significant positive effect on career adaptation, with future planning and problem-solving having the highest influence. Self-evaluation, career information, and goal-setting do not significantly impact career adaptation. Career preparation behavior has a significant positive effect on career adaptation, with the sub-factors in descending order being information gathering behavior, goal achievement behavior, and tool preparation behavior. In the mediation test, career preparation behavior partially mediates the effects, mainly through problem-solving and future planning influencing information gathering and goal achievement behaviors, thereby enhancing students' interest in careers, self-behavioral control, curiosity about future developments, and confidence. Thus, problem-solving and future planning in career decision self-efficacy are critical for enhancing students' career adaptation and achieving high-quality employment.
Factors Affecting the Implementation of Cybersecurity in the Philippine Coast Guard
Authors: Apillanes Jr. Leopoldo DG
Published: May 2024

This study investigates the factors influencing the implementation of cybersecurity in the Philippine Coast Guard (PCG) to ensure national security and maritime safety. The research focused on policies, circulars, developmental plans, equipment, and human resources. A mixed-methods approach was used, collecting quantitative data through a survey of 90 MARSLEC personnel to assess their cybersecurity awareness and perceptions of current measures. Qualitative insights were obtained from in-depth interviews with deputy commanders of MARSLEC units. The results revealed key obstacles: unclear policies and circulars, limited budget and resources for cybersecurity equipment, and insufficient specialized training and skilled personnel. Despite these challenges, there was a strong commitment from PCG leadership to prioritize cybersecurity. Effective collaboration with other agencies and organizations was deemed crucial. The study recommended addressing these challenges by clarifying policies, optimizing resource allocation, and implementing continuous training and awareness programs. By improving cybersecurity readiness, the PCG could better safeguard national interests, maritime assets, and personnel against evolving cyber threats. These measures are essential for enhancing the PCG's cybersecurity posture and ensuring resilient maritime operations.
La relación entre la marginalidad urbana y la brecha digital. El caso de Ciudad Juárez, Chihuahua, México, 2020
Authors: Martínez-Torres Yesua , Fuentes-Flores César Mario
Published: May 2024

Objetivo: analizar la relación entre la marginalidad urbana y la brecha digital regional en Ciudad Juárez, México. Metodología: se construyó un índice de marginalidad urbana mediante la técnica de componentes principales, y se estimaron ocho modelos de regresión de mínimos cuadrados ordinarios y rezago espacial. Se utilizó la información censal de 2020 y el Inventario Nacional de Vivienda 2020 del Instituto Nacional de Estadística y Geografía. Resultados: el análisis demuestra que la relación entre la marginalidad urbana y la brecha digital es positiva y significativa, sobre todo para las viviendas que no disponen de telefonía móvil ni de internet. Valor: el estudio contribuye de manera empírica a comprender la forma en que la falta de internet y de dispositivos electrónicos afecta las áreas marginales, sobre todo en el contexto de ciudades fronterizas donde hay grandes áreas de este tipo. Limitaciones: el análisis solo se consagra a explicar los efectos de la brecha digital en Ciudad Juárez y deja de lado otras ciudades de la frontera México-Estados Unidos. Además, solo recurre a un primer debate acerca de la brecha digital el cual versa sobre la disponibilidad de tecnología. Conclusiones: los resultados dan cuenta de que para las personas que residen en áreas marginales, la falta de tecnología agrava su condición de marginalidad en la ciudad.
El apolíneo Alfonso Reyes y el dionisíaco José Vasconcelos: encuentros y desencuentros
Authors: Garciadiego Javier
Published: May 2024

En este ensayo, Javier Garciadiego, especialista en estudios de la Revolución Mexicana, va desgranando las diferencias que marcaron la vida de ambos personajes desde su infancia y juventud. Mientras Vasconcelos era “un empleado aduanal de rango mediano”, el de Reyes fue Bernardo Reyes, secretario de Guerra y “duradero gobernador de Nuevo León”, durante el largo gobierno de Porfirio Díaz. El primero se formó con los libros que su católica madre sugería y el otro con los volúmenes “encuadernados” de la biblioteca de su padre. Aunque amigos, ambos discutían constantemente por razón de sus posiciones intelectuales.
BlockEdge: Building Bridges to Safe and Efficient Distributed Systems
Authors: Saxena Amit
Published: May 2024

Abstract: In the ever-evolving landscape of distributed systems, ensuring safety, efficiency, and scalability remains a paramount challenge. BlockEdge emerges as a pioneering framework designed to address these critical issues by leveraging the principles of blockchain technology and advanced consensus mechanisms. This abstract outlines the key features, innovations, and potential impacts of BlockEdge on the realm of distributed computing. BlockEdge integrates blockchain's immutable ledger properties with a novel consensus algorithm tailored for distributed systems. Unlike traditional blockchain applications that prioritize decentralization for financial transactions, BlockEdge focuses on enhancing the performance and reliability of distributed applications. The framework employs a hybrid consensus model that combines Byzantine Fault Tolerance (BFT) with Proof-of-Stake (PoS), optimizing both security and energy efficiency. A standout feature of BlockEdge is its modular architecture, which allows seamless interoperability between different types of distributed networks. This modularity facilitates the integration of various consensus protocols, catering to the specific needs of diverse applications, from IoT networks to large-scale data processing systems. By enabling secure and efficient cross-chain communication, BlockEdge effectively mitigates the silo effect prevalent in current distributed system designs.
A Review of Datasets for 3D Indoor Modeling
Authors: Medhe Aditya
Published: May 2024

Abstract: Indoor modeling has witnessed a substantial transformation in recent years, driven by advancements in 3D sensing technologies and data processing techniques. Point cloud datasets, representing detailed geometric information of indoor environments, play a pivotal role in enabling various applications such as architectural design, navigation, and augmented reality, and Building Information Modeling (BIM). This paper provides a comprehensive overview and comparision of the stateof-the-art datasets specifically curated for indoor modeling.
Design & Fabrication of Vertical Surface Cleaner
Authors: Khosare Sairaj , Dhame Anurag , Parate Ayush , Misal Shankar , Dube Abhinay , Dube Prof. A.V.
Published: May 2024

Abstract: The Wall Climbing Robot designed in this study to combines the innovative propulsion system of propellers with the traditional locomotion method of wheels to achieve versatile and efficient mobility on both vertical and horizontal surfaces. By integrating propellers and wheels, the robot can seamlessly transition between climbing walls and moving along flat surfaces. The hybrid design not only enhances the robot's mobility but also optimizes its energy efficiency, making it suitable for prolonged missions in various environments. This research explores the synergistic integration of propellers and wheels, showcasing the robot's adaptability in real- world applications such as surveillance, inspection, and maintenance tasks in both indoor and outdoor scenarios. The developed Wall Climbing Robot presents a significant advancement in robotic mobility, offering a promising solution for complex tasks in diverse settings
Assessment of Night Food Market - A Case Study of Puri, Odisha
Authors: Senapati Bedprakash , Swain Mrs. Swapna Sarita , Dhal Mr. Rohan
Published: May 2024

Abstract: This study accessess the night food market in Puri area, The research explores the unique features of the Puri market scene during night time using a case study methodology and evaluate the assessment of the night food market. This report attempts to paint a clear picture of the viability and potential impact of a night food market in the puri area through in depth analysis and data driven insights. The ultimate objective is to support the creation of an inclusive, sustainable tourism model that enhances the experience for tourists while empowering local communities
A Descriptive Study on Performance Evaluation of Sewage Treatment System
Authors: Samal Amisha , Sahoo Chitrabhanu , Pattnaik Surajit
Published: May 2024

Abstract: As The rapid expansion of modern housing and industrialization around the cities has polluted environment. This trend was observed in many developed countries in the beginning of nineteenth century which resulted in the contamination of air, water, soil etc. with pollutants. If the pollutants are released in the environment and left untreated they would cause serious diseases in both humans and animals. Large scale pollution of water bodies around the globe became a major problem due to release of industrial and domestic waste directly in water streams. To prevent the leaching of pollutants in the ground water scientist developed various methods of wastewater treatment based on the hazardous chemicals and microorganisms, which were present in the untreated water. Modern sewage treatment plants were installed in big cities to treat the water released from households. Most STPs were designed based on the stringent criteria to check the pollutants levels in the treated water so that when it is released or recycled it is safe to the environment. Modern day STP plants have a high cost of operation due to huge power consumption. In order to reduce the pollutant levels in the wastewater this study was conducted using a Eco Bio Block (EBB) techniques with aeration and without aeration. A comparison of EBB was also carried out with MBBR technique. Our results show that when EBB technique was applied with aeration it is effective in reducing pollutant levels in the wastewater akin to MBBR. In addition, we tested the EBB without aeration and found that the treated waste water has relatively low levels of BOD, COD and turbidity, suggesting that the treated water can be utilized for landscaping and horticulture activities. Overall, the outcomes from this study are encouraging to adopt EBB in smaller towns and in small housing societies to treat the wastewater prior to release. The paper focuses on reviewing the various sewage treatment methods and their results.
RESSAM AHMET YEŞİL’İN “DERİNLERE YOLCULUK” ADLI ESERİNİN HARTMANN’IN KATMANLAR TEORİSİNE GÖRE İNCELENMESİ
Authors: Gönülay Çalımlı Zeynep , Şahin Serdar
Published: May 2024

Ontoloji, varlığı inceleyen felsefenin bir dalıdır ve tarih boyunca birçok düşünür bu alana katkıda bulunmuştur. 20. yüzyılda yeniden ilgi gören ontoloji, ayrı bir felsefe alanı haline gelmiştir. Bu dönemde, varlığın incelenmesine yeni bakış açıları getirilmiştir. Hartmann, önceki düşünürlerin görüşlerini geliştirerek ontolojiyi metafiziksel bir olgudan çıkarıp sorgulanan bir bilim haline getirmiştir. Sanat bağlamında ontoloji, sanatsal yaratımın doğasını, sanatçı ile eser arasındaki ilişkiyi ve eserlerin anlamını anlamada önemli bir rol oynar. Hartmann'ın estetik düşüncelerinde duygu yerine estetik nesne vardır. Her sanat eseri, alıcısına farklı duygular yaşatır ve kendine özgü bir değer içerir. Estetik değere ulaşmak için estetik nesnenin çözümlenmesi ve nesnel yapının katmanlarının incelenmesi gerektiğini savunur.

Bu bağlamda, seçilen eser "Derinlere Yolculuk", Mersin'li ressam Ahmet Yeşil'in önemli bir yapıtıdır. Bu eser, 1996 yılında Deniz Kuvvetleri Komutanlığı'nın düzenlediği yarışmada ödül almış ve şu anda İstanbul Deniz Müzesi koleksiyonunda yer almaktadır. Bu çalışmada, seçilen eser Hartmann'ın estetik anlayışı çerçevesinde katmanlar teorisine göre derinlemesine incelenmektedir.
Theatre about science. Theory and practice
Authors: Glester Andrew
Published: May 2024

“Theatre About Science. Theory and Practice” is a result of the Theatre About Science Conference, held in November 2021 in Coimbra, Portugal. Most of the articles build upon presentations given at the conference, but some were written specifically for the publication.
Geometric Investigation of Three Thin Shells with Ruled Middle Surfaces with the Same Main Frame
Authors: Gbaguidi Aisse Gerard L. , Aleshina Olga O. , Mamieva Iraida A.
Published: May 2024

It is proved and illustrated that by taking the main frame of the surface, consisting of three plane curves placed in three coordinate planes, three different algebraic surfaces with the same rigid frame can be designed. For the first time, one three of new ruled surfaces in a family of five threes of ruled surfaces, formed on the basis of some shapes of hulls of river and see ships, which, in turn, are projected in the form of algebraic surfaces with a main frame of three superellipses or of three other plane curves, is under consideration in detail with a standpoint of differential geometry. The geometrical properties of the ruled surfaces taken as the middle surfaces of thin shells for industrial and civil engineering are presented. Analytical formulas for determination of force resultants with using the approximate momentless theory of shells of zero Gaussian curvature given by non-orthogonal conjugate curvilinear coordinates are offered for the first time. The results derived using these formulae will help to correct the results obtained by numerical methods.
Stress-Strain State of Steel Fiber-Reinforced Concrete under Compression Taking into Account Unloading from Inelastic Region
Authors: Agapov Vladimir P. , Markovich Alexey S. , Dkhar Prashanta , Golishevskaia Darya A.
Published: May 2024

The purpose of the study is to examine the physical and mechanical characteristics of steel fiber-reinforced concrete under compression, including: modulus of elasticity, Poisson ratio, values of ultimate strains under compression, values of compressive strength with different percentages of dispersed reinforcement. An experimental investigation program, which included the production of cube samples measuring 100×100×100 mm, as well as a compression test under static loading, taking into account unloading from the region of inelastic deformations, was developed and carried out. Two types of steel fiber were chosen as dispersed reinforcement: hooked end and wave shape. The volume content of steel fiber in the cube samples was 0.5, 1.0, 1.5 and 2.0 %. As a result of the investigation, the strength and deformation characteristics of steel fiber reinforced concrete under compression were obtained. Based on the experimental data, actual strain diagrams of steel fiber reinforced concrete were constructed, taking into account the type of reinforcing fibers and the percentage of reinforcing fiber. Based on the obtained diagrams, a law of deformation of steel fiber reinforced concrete is proposed, which can be described by a polynomial function of the fourth order with constant coefficients that determine the shape of the stress-strain curve. The presented research results can be used in developing a methodology for physically nonlinear analysis of steel fiber reinforced concrete elements with a percentage of dispersed reinforcement from 0.5 to 2.0 %.
Effects of NREM sleep on cortical synapses
Authors: Squarcio Fabio , Tononi Giulio , Cirelli Chiara
Published: May 2024

Converging electrophysiological, molecular, and ultrastructural evidence
supports the hypothesis that sleep promotes a net decrease in excitatory
synaptic strength, counteracting the net synaptic potentiation caused by
ongoing learning during waking. However, several outstanding questions
about sleep-dependent synaptic weakening remain. Here, we address some
of these questions by using two established molecular markers of
synaptic strength, the levels of the calcium-permeable AMPA
(Alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid) receptors
containing the GluA1 subunit, and the phosphorylation of GluA1 at serine
845. We previously found that, in the rat cortex and hippocampus, these
markers are lower after 6-8 hours of sleep than after the same time
spent awake. Here, we measure GluA1 expression in mouse cortex after 5
hours of either sleep, sleep deprivation, recovery sleep after sleep
deprivation, or selective REM sleep deprivation (32 C57BL/B6 adult mice,
16 females). We find that relative to after sleep deprivation, synaptic
GluA1 expression is lower after sleep independent of whether the mice
were allowed to enter REM sleep. Moreover, 5 hours of recovery sleep
following acute sleep deprivation are enough to renormalize GluA1
expression. In a pilot study in old mice (12 C57BL/B6 male mice,
20-month-old) we also find that GluA1 expression is high after sleep
deprivation and low after sleep and recovery sleep. Thus, the
renormalization of GluA1 expression crucially relies on NREM sleep and
can occur in a few hours of sleep after acute sleep deprivation.
Moreover, as measured by GluA1 expression, it appears that
sleep-dependent synaptic weakening is unaffected by aging.
Stratigraphy-Induced Localization of Microseismicity During CO2 Injection in Illinois Basin
Authors: Bondarenko Nikita , Podladchikov Yuri Yurivech , Williams-Stroud Sherilyn , Makhnenko Roman Y.
Published: May 2024

Subsurface fluid injection stimulates complex hydromechanical
interaction, necessitating the integration of geomechanical data across
spatial and temporal scales to consider the sophisticated behavior. The
induced seismic response is usually associated with reservoir
architecture and pre-existing features that are three-dimensional, such
as local stratigraphy, fractures, faults, and discontinuities. This
study encompasses laboratory characterization of coupled hydromechanical
response of rock cores extracted from reservoir - Mt. Simon sandstone,
basal seal - Argenta sandstone, and crystalline basement - Precambrian
rhyolite - formations in the Illinois Basin. High-resolution numerical
modeling allows to consider the three-dimensional complexity of the
injection site for Illinois Basin Decatur Project with spatial
resolution comparable to one of the active seismic surveys. The
laboratory-based porosity-permeability relation is combined with a
three-dimensional porosity distribution developed from an inversion of
active seismic data resulting in a detailed reconstruction of the
evolution of the state of stress in formations where stress measurements
are not performed. It appears that the microseismic clusters, mainly
observed in the crystalline basement during the injection, are linked to
zones experiencing more critically stressed conditions prior to
injection. These zones have a potential for reactivation during the
injection and are attributed to the specific local stratigraphy of the
injection site, as well as transfer of triggering perturbations during
the injection.
Disentangling the roles of internal atmospheric variability and ENSO on California precipitation to explain recent seasonal forecast errors
Authors: Guirguis Kristen , Hatchett Benjamin J , DeFlorio Michael J , Gershunov Alexander , Clemesha Rachel E. S. , Brandt W. Tyler , Haleakala Kayden , Castellano Christopher M , Nino Rosa Luna , Tardy Alexander , Anderson Michael , Ralph F. Martin
Published: May 2024

Water years (WY) 2017 and 2023 were anomalously wet for California, each
helping to terminate multiyear droughts. In both cases, this was
unexpected given La Niña conditions, with most seasonal forecasts
favoring drier-than-normal winters. We analyze over seven decades of
precipitation and snow records along with mid-tropospheric circulation
to identify recurring weather patterns driving California precipitation
and Sierra Nevada snowpack. Tropical forcing by ENSO causes subtle but
important differences in these wet weather patterns, which largely
drives the canonical ENSO-precipitation relationship. However, the
seasonal frequency of these weather patterns is not strongly modulated
by ENSO and remains a primary source of uncertainty for seasonal
forecasting. Seasonal frequency of ENSO-independent weather patterns was
a major cause of anomalous precipitation in WY2017, record-setting snow
in WY2023, and differences in precipitation outcome during recent El
Niño winters 1983,1998 and 2016. Improved understanding of recurrent
atmospheric weather patterns could help to improve seasonal forecasts.
Világos sejtes adenocarcinoma férfi húgycsőben. Esetismertetés = Clear cell adenocarcinoma of the male urethra-case report
Authors: Weigert Tamás , Kubik András , Keszthelyi Attila , Székely Eszter , Gesztesi László , Nagy Gábor , Nyirády Péter
Published: May 2024

Bevezetés: A világos sejtes húgycső-adenocarcinoma igen ritka entitás férfiakban. A daganat kezelésében fontos szerepet kap a radikális cysto-prostatectomia kiterjesztett kismedencei nyirokcsomó-eltávolítással, esetleges sugárkezeléssel kiegészítve. Esetismertetés: 60 éves férfinél a húgycső prostaticus és membranosus szakaszán elhelyezkedő világos sejtes adenocarcinoma miatt történt radikális műtét. A sebészi szél egyértelműen nem volt megítélhető. Posztoperatív MR-vizsgálat lokális disszemináció és recidíva gyanúját írta le. Radioterápia indult, az elváltozások regrediáltak. Következtetések: A világos sejtes húgycső-adenocarcinoma kezelése nem teljesen letisztult. Az onkoteam, illetve a posztoperatív képalkotók szerepe kiemelt. Nem megítélhető sebészi szél esetén posztoperatív sugárkezelést javaslunk.
A spermiumok DNS-fragmentációs vizsgálatának vizsgálati módszerei és szakirodalmi indikációi
Authors: Máté Gábor , Balló András , Török Attila
Published: May 2024

A férfi eredetű meddőség a meddőségi kezelésben résztvevő párok mintegy felét érintő probléma. A valóságban ez a szám sokkal nagyobb is lehet, mivel a legújabb kutatások egyre inkább alátámasztják, hogy az ismeretlen eredetű meddőség esetén (az esetek 15-30%-a), amikor a hagyományos andrológiai vizsgálatok során semmilyen problémát nem találunk, akkor sok esetben emelkedett, illetve magas spermium DNS-fragmentációs érték detektálható. Azonban nem csak ebben az esetben figyelhető meg emelkedett DNS-fragmentáció. Több kutatásban is a DNS-fragmentációs index megemelkedését tapasztalták habituális vetélő hölgyek párjainál, többszöri sikertelen lombikbeavatkozás esetén, leukocytospermia esetén, a varicocele-vel küzdőknél, magas spermium reaktív oxigénszabadgyök-értéknél stb. Kéziratunkban szeretnénk bemutatni a szakirodalomban felelhető indikációit a spermium DNS-fragmentáció vizsgálatnak és a DNS-fragmentáció vizsgálati módszereit.
A posztoperatív C-reaktív-fehérje megbízható markere a radikális cystectomia és újhólyag-képzést követő szövődmények kialakulásának?
Authors: Kertész László , Kovács Lukács , Vrecenár László , Mózes Tibor , Buzogány István , Beöthe Tamás
Published: May 2024

Bevezetés: Az izominvazív TCC kuratív terápiája lehet hólyagprezerváló kemoirradiáció, amely a maximális endoszkópos tumoreltávolítást követően, vagy az endoszkópos műtéttel kombinálva trimodális terápiaként történhet. A radikális hólyageltávolítás a másik út, amikor a daganatos hólyagot, a regionális nyirokcsomók kiterjesztett eltávolításával és legtöbbször bél felhasználásával történő vizeleteltereléssel kombináltan kell elvégezni. A szerzők az utóbbi a betegek számára nagy megterhelést jelentő beavatkozások alkalmával vizsgálták az előforduló gasztrointesztinális komplikációk lehetséges prediktorait, azok egymáshoz viszonyított, megbízhatóságát különös tekintettel a C-reaktív-proteinre. Anyag és módszer: A feldolgozott időszakban történt 254 radikális cystectomia közül 51 beteg került bevonásra a vizsgálatba. A beválasztás feltételei: Bricker- vagy Studer-hólyagképzés, medián laparotomia. A kizárási kritériumok a gyulladás, fertőzés, valamint a nem szteroid gyulladáscsökkentők és folyamatos antibiotikumszedés voltak. A részletes tájékoztatást követően a beleegyező betegeknek az operáció előtt, valamint operáció után az 1., 3., 6., 9., 14. napon a 3., 9. hónapban és évenként egészen az 5 éves túlélésig megtörtént a szérum CRP, WBC, TNFa, szolubilis TNFa-receptor I., IL-6, in vitro TNFaés PGE2-szint meghatározása. Jelenleg a monitorozott összes paraméter közül a CRP- és WBC-szint változását vizsgáltuk és hasonlítottuk össze a nonszeptikus, szeptikus és anasztomózis-elégtelen – leakage – (AL) csoportok esetében, mint a szövődmény kialakulásának lehetséges és biztonságos prediktorát. Eredmények: A vizsgálatba bevont betegek esetében 5 betegnél vékonybélvarrat-elégtelenség fordult elő. Az említett eltérések kialakulásának mediánja a posztoperatív 15. napra esett. A CRP-szint emelkedése minden esetben megbízhatóan jelezte a nemkívánatos eseményt, szinkronban a hat ugyancsak vizsgált és szignifikánsnak bizonyult szérum paraméter a WBC, TNFa, szolubilis TNFa-receptor I., IL-6, in vitro TNFa és PGE2 szintjének változásával. A szérum CRP-szintek mindhárom csoportban párhuzamosan változtak a post op. 12-13. napig, ahol az anasztomózis-elégtelen csoport CRP-je szignifikánsan a másik két csoport fölé emelkedett. Következtetés: A CRP változásának monitorizálása, akár önmagában is képes lehet az anasztomózis-elégtelenség, vagy a beteg sorsát markánsan befolyásolni képes szövődmények előre jelzésére. Egyszerű, a hétköznapokban rutinszerűen alkalmazható vizsgálat, amely által csökkenthető a szövődmények súlyossága, a hospitalizáció, valamint a mortalitás. A CRC-műtétek szövődményeit vizsgáló tanulmányok alapján a CRP a posztoperatív szeptikus események megfelelő markere, sőt az anasztomózis-elégtelenség prediktorának is tekinthető.
Vesedaganat tüdőmetasztázisát utánzó Dirofilaria-fertőzés
Authors: Czakó Márton , Buzogány István
Published: May 2024

Bevezetés: A vesesejtes karcinóma (RCC) áttétei leggyakrabban, 50-60%-ban a tüdőben szoliter vagy multiplex nodulusok formájában jelentkeznek. Vesedaganatos betegek kontrollja során gyakran előfordul, hogy az alapbetegség propagációjának vélt metasztázisgyanús eltérések nehezítik a helyes diagnózist és az optimális terápia megválasztását. Esetismertetés: RCC miatt radikális nephrectomián átesett betegünk protokoll szerinti utánkövetése során képalkotó vizsgálatokon merült fel egy szoliter tüdőmetasztázis lehetősége. A CT-kép alapján az onkoteam már onkológiai kezelést tervezett; azonban tekintettel a beteg jó általános állapotára, az egyedüli áttét lehetőségére, a tüdőben való elhelyezkedése alapján kezdeményezésünkre operálhatónak véleményezett góc műtéti eltávolítása történt az Országos Onkológiai Intézetben. A reszekátum szövettani vizsgálata azonban meglepetésre a Magyarországon egyelőre ritka előfordulású, elsősorban a Mediterráneumban gyakori Dirofilaria-parazita okozta tüdőinfarktust igazolt, malignitásra utaló jel nélkül. Megbeszélés: Napjainkban még sporadikusnak tekinthető ez a kórkép, ám az utóbbi évek tapasztalatai alapján a növekvő humán fonálféreg-fertőzés esetszám miatt a tüdőben leírt, akár vesedaganat áttétjére gyanús szoliter terime hátterében érdemes lehet gondolni erre a zoonosisra is. Az előrehaladott, áttétes vesedaganat onkológiai kezelési lehetőségei az utóbbi években számos új lehetőséggel bővültek, amelyek optimizmusra adnak okot. A ritka eset bemutatása mellett további célunk volt az áttétes vesedaganatok kezelési lehetőségeinek rövid áttekintése is.
Operational semantics in a domain-specific robot control language: A pedagogical use case
Authors: Steingartner William , Novitzká Valerie
Published: May 2024

In this paper, we focus on some aspects of structural operational semantics for a selected domain-specific language for robot control. After defining a syntax for two independent languages for control of a robot?s movements, we define a structural operational semantics for them. The integrated part of structural operational semantics is abstract implementation, which consists of defining abstract machine and transformation of a programming language to abstract machine instructions. The achieved results as well as the mentioned research are a part of the research in the field of semantic methods, where we focus on the formalization of semantic methods for software engineering. This area is also very important for the training of students and young IT experts because the semantic methods can help to understand program behavior and detect errors in program design. To make the teaching of formal semantics in the field of domain-specific languages more attractive, we have also prepared an application that serves to visualize the individual steps of the program on an abstract machine ? simulation of translated code with visualization of a robot?s movement.
Liftings from a para-Sasakian manifold to its tangent bundles
Authors: Khan Mohammad
Published: May 2024

The purpose of the present paper is to study the liftings of a quarter
symmetric non-metric connection from a para-Sasakian manifold to its tangent
bundles. By liftings, some results of the curvature tensor, projective
curvature tensor, concircular curvature tensor and conformal curvature
tensor wrt a quarter symmetric non-metric connection in a P-Sasakian
manifold to its tangent bundles are obtained.
Existence of positive solutions for singular fractional boundary value problems with p-Laplacian
Authors: Hamal Nuket , Erkan Furkan
Published: May 2024

In this paper, we obtain the existence of positive solutions for the singular
fractional boundary value problem with p-Laplacian. The existence of
positive solutions is established using the Avery-Peterson fixed point
theorem. In addition, we include an example for the demonstration of our
main result.
Teletrabajo y gestión de equipos a distancia: evaluación de prácticas y políticas para un futuro del trabajo flexible
Authors:   Instituto Tecnológico Universitario Cordillera, Ecuador., Espinosa Cevallos Alejandra
Published: May 2024

El teletrabajo y la gestión de equipos a distancia se han convertido en aspectos fundamentales para el futuro del trabajo flexible. El objetivo general de este estudio fue evaluar las prácticas y políticas actuales en este ámbito. La metodología utilizada incluyó un análisis de contenido de diversas fuentes bibliográficas relevantes, así como la aplicación de técnicas de codificación y categorización para identificar patrones, tendencias y áreas de mejora en la gestión del teletrabajo y los equipos remotos. Los resultados principales destacan la importancia de políticas flexibles y herramientas tecnológicas en la gestión remota de equipos, la necesidad de estrategias para mejorar la colaboración virtual y la relevancia de un liderazgo efectivo en equipos virtuales.
Human intelligence and artificial intelligence and the challenges of biases in ai algorithms
Authors: Fernandes Erika Ribeiro , Graglia Marcelo Augusto Vieira
Published: May 2024

This article acknowledges the profound transformations that Artificial Intelligence imposes on society. A descriptive-exploratory study aims to discuss algorithmic biases and understand their impacts on society. The article starts from the understanding of human intelligence and learning from a pluralistic perspective, based on the analysis of literary works and scientific articles. This approach provides a context in which AI and machine learning can be conceived from an innovation perspective for the common good. The critical analysis emphasizes the need for ethical approaches in the development of these systems. The topics discussed highlight the importance of a multidimensional approach in mitigating algorithmic biases. From data selection to audits and accountability, diversity of perspectives, both in datasets and development teams, is crucial. The implementation of continuous training and human supervision reflects a continuous commitment to transparency and fairness in artificial intelligence. These integrated strategies are essential for the ethical, transparent, and equitable development of AI. This holistic approach, involving diverse skills and people, continuous training, and vigilant oversight, is vital to ensure the ethical use of AI for the collective well-being.
Study of the social, environmental and economic dimensions in rural communities
Authors: Batista Géssica Danielle , Rosini Alessandro Marco , Pedrinho Denise Renata , Palmisano Angelo
Published: May 2024

The objective of this article was to carry out an analysis of public policies related to rural settlements, and correlate them with the Sustainable Development Goals (SDGs) and ESG and present alternatives that contribute to the local development of rural settlements. The methodology used consisted of qualitative research and exploratory analysis with participant observation, conducted in the Vale do Arinos Settlement Project, Line Five, located in the Municipality of Juara, located in the northern region of the state of Mato Grosso. This study analyzed the factors that influence the social, environmental and economic development of rural producers in the aforementioned Settlement Project. To carry out this analysis, the Grounded Theory technique was also applied. This research contributes to the improvement and development of rural settlement communities. When examining Settlement Project, it is clear that rural producers face difficulties in subsisting and thriving, especially in a market characterized by volatility and a lack of appreciation for their products. When relating the SDGs with Project, an unfavorable situation is observed with regard to the social, environmental and economic tripod in this community.
Problematizando a noção de imersão em letramentos digitais no contexto da pandemia de COVID-19
Authors: Silva Francisco Gabriel Cordeiro da , Costa Marco Antônio Margarido
Published: May 2024

Este artigo objetiva analisar e discutir as práticas letradas digitais de licenciandos durante a realização do estágio supervisionado obrigatório no período de setembro a dezembro de 2020 do curso de Letras – Língua Inglesa, de uma universidade pública localizada no interior do Nordeste. Devido à pandemia de COVID-19, o componente de Estágio de Língua Inglesa: 3º ano do Ensino Médio ocorreu de maneira completamente remota, por meio de tecnologias digitais. Para o enfoque teórico-metodológico deste estudo, selecionamos alguns dados e focalizamos especialmente no entendimento dos estagiários sobre a noção de imersão em letramentos digitais durante a execução das etapas constituintes do estágio. Após a análise dos dados, foi possível constatar que, diante do fato de que a maioria dos estagiários afirmou que não houve imersão em letramentos digitais neste período, a apreensão das práticas letradas realizadas se coaduna com a perspectiva autônoma, referindo-se à noção de desenvolvimento de habilidades, neste caso, com os aparatos e recursos digitais, opondo-se à perspectiva sociocultural e ideológica (Buzato, 2006; Kleiman, 1995; Lankshear, Knobel, 2011; Street, 1986, 2010, 2012).
Ensino de inglês para fins acadêmicos
Authors: Vial Ana Paula Seixas , Acorinti Wesley Henrique , Sarmento Simone
Published: May 2024

Considerando a necessidade de engajar-se em inglês na universidade (Hyland, 2009), este estudo investiga as perspectivas de professores iniciantes sobre o ensino de Inglês para Fins Acadêmicos (IFA). Os resultados desta pesquisa qualitativa (Mason, 2002) e interpretativa (Erickson, 1990), baseada em entrevistas semiestruturadas, revelam que esses professores entendem IFA como um modo de comunicação centrado em habilidades para a participação acadêmica. Por um lado, os professores apontam que os livros didáticos não suprem completamente as necessidades de uma aula de IFA. Por outro lado, reconhecem a relevância desses materiais para a construção de currículos. Ademais, reconhecem a importância da parceria com os estudantes para abordar as diferenças disciplinares. Ainda, explicitam a dificuldade de ensinar IFA para estudantes com níveis básicos de proficiência, porém encontram estratégias para lidar com isso. Esta pesquisa tem implicações para a formação de professores para o ensino de IFA.
Epidemiological Profile and Risk Factors for Retinopathy in Moroccan Type 2 Diabetics
Authors: GUERBOUB Ahmed anas , HALOUACHE Ali , MOUZARIA Yassine , ISOUANI Jade , ERRAHALI Yassine
Published: May 2024

Objective: To evaluate the ophthalmic impact, compare characteristics, and identify risk factors related to diabetic retinopathy (DR) in patients seen for the first time in consultation. Patients and methods: This descriptive cross-sectional study was conducted during the period from June to December 2018, of a representative sample of 156 diabetics recruited in the department of endocrinology diabetology and metabolic diseases of the Military Hospital of Instruction Mohamed V of Rabat. Results: Among the 156 patients included in our study, 86 (55.1%) had a normal eye fundus, while 70 (44.8%) had DR. Glycemic control, age of diabetes, as well as diabetic nephropathy and abdominal obesity were risk factors (OR>1, p<0.05), while physical activity and development of lean body mass are protective factors (OR<1, p>0.05) of diabetic retinopathy. Conclusion: Our study reflects the epidemiological profile of the Moroccan population, where the prevalence of DR remains high, with poor control of risk factors.