bluuebunny/crossref_metadata_2025 huggingface dataset:
Convective and conductive thermal homogenization for non-saturated porous building materials: Application on the thermal conductivity tensor
Authors: Bennai Fares , Abahri Kamilia , Belarbi Rafik , Tahakourt Abdelkader
Published: November 2016

Porous materials possess a complex structure on a microscopic scale and present strong heterogeneities, which makes their precise study extremely complex. In fact, the macroscopic behavior of these materials is strongly dependent on mechanisms that act to the scale of their components. The present work focus on the development of a macroscopic conductive and convective fluid heat transfer model, with a heat source in the unsaturated porous materials. This model is established by periodic homogenization of energy conservation equations written on a microscopic scale in each phase (solid, liquid and gas). The resulting input parameters formulations of the submodel were explicitly identified. Numerical calculations of the homogenized thermal conductivity tensor are performed on a representative 3-D elementary cell of the porous medium. Finally, a sensitivity study of this tensor depending of the variation of the water content and porosity of the concerned elementary cell has been performed. This sensitivity is required to be considered in simulations to better understand the behavior of building materials and improve the prediction of energy performance.
Waste heat recovery from diesel engine using custom designed heat exchanger and thermal storage system with nanoenhanced phase change material
Authors: Wilson John , Singh Abhishek , Singh Abhinay , Ganapathy Subramanian
Published: November 2016

In this research study an attempt has been made to recover the heat energy of the exhaust gas from a Diesel engine, using a triangular finned shell and tube heat exchanger with segmental baffle at 20?, and efficiently store as sensible and latent heat energy using thermal storage tank having phase change material with CuO nanoparticles. The nanoparticles and the phase change material form the nanoparticle-enhanced phase change material and mainly the thermal conductivity of the phase change material can be enhanced through the dispersion of the nanoparticles. The temperature variations of the heat transfer fluid in the heat recovery heat exchanger with various load conditions of the Diesel engine are studied. The performance of the heat exchanger is evaluated using heat extraction rate and effectiveness. Evaluation of the performance of the thermal storage system can be analyzed by using the total heat energy stored and charging rate during the charging period for the selected nanoparticle-enhanced phase change material.
Effect of cetane improver addition into diesel fuel: Methanol mixtures on performance and emissions at different injection pressures
Authors: Candan Feyyaz , Ciniviz Murat , Ors Ilker
Published: November 2016

In this study, methanol in ratios of 5-10-15% were incorporated into diesel fuel with the aim of reducing harmful exhaust gasses of Diesel engine, di-tertbutyl peroxide as cetane improver in a ratio of 1% was added into mixture fuels in order to reduce negative effects of methanol on engine performance parameters, and isobutanol of a ratio of 1% was used as additive for preventing phase separation of all mixtures. As results of experiments conducted on a single cylinder and direct injection Diesel engine, methanol caused the increase of NOx emission while reducing CO, HC, CO2, and smoke opacity emissions. It also reduced torque and power values, and increased brake specific fuel consumption values. Cetane improver increased torque and power values slightly compared to methanol-mixed fuels, and reduced brake specific fuel consumption values. It also affected exhaust emission values positively, excluding smoke opacity. Increase of injector injection pressure affected performances of methanol-mixed fuels positively. It also increased injection pressure and NOx emissions, while reducing other exhaust emissions.
Techno-economic evaluation of residue exhaustion in batch rectification ethanol production plant
Authors: Jacimovic Branislav , Genic Srbislav , Budimir Nikola , Jaric Marko
Published: November 2016

This paper presents the techno-economic optimization of batch plant for production of rectified alcohol based on the concentration of ethanol in residue. The aim of the analysis was to determine the extent to which it is economically profitable to exhaust the residual liquid in boiler. The "profit production" criterion is used for calculations.
Performance comparison of aboveground and underground solar ponds
Authors: Sogukpinar Haci , Bozkurt Ismail , Karakilcik Mehmet
Published: November 2016

This paper deals with the modeling of two different solar ponds which has some different structural parameters such as aboveground and underground, and its performance evaluation. The solar pond system generally consists of three zones, and the densities of these zones decrease from the bottom of the pond to the surface. The most significant decrease in the density distribution of the salt between bottom and up of the pond is the gradient zone. The convective heat loss in the solar pond is prevented with this zone. In this study, aboveground and underground solar ponds were modeled at the same dimensions, but different structural parameters in the same conditions. In this model, the temperature distributions of the solar pond were obtained during a year. The thermal performances of the solar pond were calculated and the results were compared with an experiment. This study shows that the efficiency of the aboveground solar pond is observed to be a maximum of 25.93% in July, a minimum of 4.53% in January. Furthermore, the efficiency of the underground solar pond is observed to be a maximum of 21.49% in July, a minimum of 6.55% in January. This study indicates that the underground construction of solar ponds, designed to be insulated using appropriate insulation materials, is found to be more efficient with respect to the aboveground pond.
Laser doppler velocimetry and confined flows
Authors: Ilic Jelena , Ristic Slavica , Sreckovic Milesa
Published: November 2016

Finding the mode, in which two component laser Doppler velocimetry can be applied to flows confined in cylindrical tubes or vessels, was the aim of this study. We have identified principle issues that influence the propagation of laser beams in laser Doppler velocimetry system, applied to flow confined in cylindrical tube. Among them, the most important are influences of fluid and wall refractive indices, wall thickness and internal radius ratio and beam intersection angle. In analysis of the degrees of these influences, we have applied mathematical model, based on geometrical optics. The separation of measurement volumes, that measure different velocity components, has been recognized as the main drawback. To overcome this, we propose a lens with dual focal length ? primary focal length for the measurement of one velocity component and secondary focal length for the measurement of the other velocity component. We present here the procedure for calculating the optimal value of secondary focal length, depending on experimental set-up parameters. The mathematical simulation of the application of the dual focal length lens, for chosen cases presented here, confirmed the accuracy of the proposed procedure.
Erratum: The article „Congenital upper eyelid coboloma with ipsilateral eyebrow hypoplasia” [Urodjeni defekt gornjeg kapka sa istostranom hipoplazijom obrve]. Vojnosanit pregl 2012; 69(9): 809-811. (DOI:10.2298/VSP1209809V).
Authors: Editorial E
Published: November 2016

The authors and their affiliations were listed as follows: Dejan Vulovic+, Marijan Novakovic??, Tatjana Sarenac?, Mirjana Janicijevic-Petrovic?, Nenad Petrovic?, Suncica Sreckovic?, Sasa Milicevic?, Branislav Piscevic? +Centre for Plastic Surgery, ?Clinic for Ophthalmology, Clinical Centre Kragujevac, Kragujevac, Serbia; ?Clinic for Plastic Surgery and Burns, Military Medical Academy, Belgrade, Serbia; ?Medical Faculty of the Military Medical Academy, University of Defence, Belgrade, Serbia Listed the authors and their affiliations should read as: Dejan Vulovic+, Marijan Novakovic??, Tatjana Sarenac?, Mirjana Janicijevic-Petrovic?, Nenad Petrovic?, Suncica Sreckovic?, Sasa Milicevic?, Branislav Piscevic? +Centre for Plastic Surgery, ?Clinic for Ophthalmology, Clinical Centre Kragujevac, Kragujevac, Serbia; ?Clinic for Plastic Surgery and Burns, Military Medical Academy, Belgrade, Serbia; ?Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia

 Link to the corrected article 10.2298/VSP1209809V
Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution
Authors: Ehrlund Anna , Mejhert Niklas , Björk Christel , Andersson Robin , Kulyté Agné , Åström Gaby , Itoh Masayoshi , Kawaji Hideya , Lassmann Timo , Daub Carsten O. , Carninci Piero , Forrest Alistair R.R. , Hayashizaki Yoshihide , Sandelin Albin , Ingelsson Erik ,   FANTOM Consortium, Rydén Mikael , Laurencikiene Jurga , Arner Peter , Arner Erik
Published: November 2016

White adipose tissue (WAT) can develop into several phenotypes with different pathophysiological impact on type 2 diabetes. To better understand the adipogenic process, the transcriptional events that occur during in vitro differentiation of human adipocytes were investigated and the findings linked to WAT phenotypes. Single-molecule transcriptional profiling provided a detailed map of the expressional changes of genes, enhancers, and long noncoding RNAs, where different types of transcripts share common dynamics during differentiation. Common signatures include early downregulated, transient, and late induced transcripts, all of which are linked to distinct developmental processes during adipogenesis. Enhancers expressed during adipogenesis overlap significantly with genetic variants associated with WAT distribution. Transiently expressed and late induced genes are associated with hypertrophic WAT (few but large fat cells), a phenotype closely linked to insulin resistance and type 2 diabetes. Transcription factors that are expressed early or transiently affect differentiation and adipocyte function and are controlled by several well-known upstream regulators such as glucocorticosteroids, insulin, cAMP, and thyroid hormones. Taken together, our results suggest a complex but highly coordinated regulation of adipogenesis.
Biomechanical assessment of the effects of vertebral distraction-fusion techniques on the adjacent segment of canine cervical vertebrae
Authors: Hakozaki Takaharu , Ichinohe Tomu , Kanno Nobuo , Yogo Takuya , Harada Yasuji , Inaba Tadashi , Kasai Yuichi , Hara Yasushi
Published: November 2016

OBJECTIVE To assess effects of vertebral distraction-fusion techniques at a treated segment (C5-C6) and an adjacent segment (C4-C5) of canine cervical vertebrae.

SAMPLE Cervical vertebrae harvested from cadavers of 10 skeletally mature Beagles.

PROCEDURES Three models (intact, titanium plate, and polymethylmethacrylate [PM MA]) for stabilization of the caudal region of the cervical vertebrae (C4 through C7) were applied to the C5-C6 vertebral segment sequentially on the same specimens. Biomechanical assessments with flexion-extension, lateral bending, and axial rotational tests were conducted after each procedure. Range of motion (ROM) for a torque load applied with a 6-axis material tester was measured at C4-5 and C5-6 and calculated by use of a 3-D video measurement system.

RESULTS In both the plate and PMMA models, ROM significantly increased at C4-5 and significantly decreased at C5-6, compared with results for the intact model. The ROM at C5-6 was significantly lower for the plate model versus the PMMA model in lateral bending and for the PMMA model versus the plate model in axial rotation. Conversely, ROM at C4-5 was significantly higher in axial rotation for the PMMA model versus the plate model. No significant differences were identified in flexion-extension between the PMMA and plate models at either site.

CONCLUSIONS AND CLINICAL RELEVANCE Results of this study suggested that vertebral distraction and fusion of canine vertebrae can change the mechanical environment at, and may cause disorders in, the adjacent segment. Additionally, findings suggested that effects on the adjacent segment differed on the basis of the fusion method used.
Feasibility, repeatability, and safety of ultrasound-guided stimulation of the first cervical nerve at the alar foramen in horses
Authors: Mespoulhès-Rivière Céline , Brandenberger Olivier , Rossignol Fabrice , Robert Céline , Perkins Justin D. , Marie Jean-Paul , Ducharme Norm
Published: November 2016

OBJECTIVE To develop and assess the feasibility, repeatability, and safety of an ultrasound-guided technique to stimulate the first cervical nerve (FCN) at the level of the alar foramen of the atlas of horses.

ANIMALS 4 equine cadavers and 6 clinically normal Standardbreds.

PROCEDURES In each cadaver, the FCN pathway was determined by dissection, and any anastomosis between the first and second cervical nerves was identified. Subsequently, each of 6 live horses underwent a bilateral ultrasound-guided stimulation of the FCN at the alar foramen 3 times at 3-week intervals. After each procedure, horses were examined daily for 5 days.

RESULTS In each cadaver, the FCN passed through the alar foramen; a communicating branch between the FCN and the accessory nerve and anastomoses between the ventral branches of the FCN and second cervical nerve were identified. The anastomoses were located in the upper third of the FCN pathway between the wing of the atlas and the nerve's entry in the omohyoideus muscle. Successful ultrasound-guided electrical stimulation was confirmed by twitching of the ipsilateral omohyoideus muscle in all 6 live horses; this finding was observed bilaterally during each of the 3 experimental sessions. No complications developed at the site of stimulation.

CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that ultrasound-guided stimulation of the FCN at the alar foramen appears to be a safe and straightforward procedure in horses. The procedure may have potential for use in horses with naturally occurring recurrent laryngeal neuropathy to assess reinnervation after FCN transplantation or nerve-muscle pedicle implantation in the cricoarytenoideus dorsalis muscle.
Building the Green Economy
Authors: Barbier Edward B.
Published: November 2016

The green economy in North America is at a critical crossroads. Will it foster a new wave of economy-wide innovation, employment, and green growth, or will green sectors remain a niche within an overall “brown” economy? Much will depend on what replaces the current “policy void” since the green stimulus policies of the Great Recession. Currently, three major market disincentives remain: environmentally harmful subsidies, inadequate market-based incentives, and insufficient public support for private R&D. A policy strategy for green growth requires phasing out and rationalizing subsidies, instigating effective market-based instruments, and allocating the revenues raised to enhance green innovation.
Canada in a Low-Carbon World: Impacts on New and Existing Resources
Authors: Leach Andrew
Published: November 2016

Moving to a low-carbon future will create challenges for Canada's fossil-fuel industries, but opportunities in the form of a new market for low-carbon goods and services. The challenges for the resource sector will vary across commodities. Competition in the new market for low-carbon goods and services will be tough; sustained competitive advantage will be difficult to maintain due to capital mobility. With these challenges in mind, this article proposes three questions for Canadians looking ahead to a low-carbon future. First, how large will the market for low-carbon goods and services be? Second, where are Canada's advantages likely to lie in serving these markets? Finally, what are the roles for Canada's existing natural-resource industries in a low-carbon economy, and what are the strategies to maximize the value of these resources?
Canada's Low-Innovation Equilibrium: Why It Has Been Sustained and How It Will Be Disrupted
Authors: Nicholson Peter
Published: November 2016

The paper begins with some basic innovation definitions and quickly reviews evidence of the relatively weak innovation performance of Canadian business. The core of the paper develops a thesis that explains why Canadian industry, on the whole, has not emphasized innovation in its business strategies but has prospered nonetheless. This raises the question of whether Canada's low-innovation equilibrium can persist in the face of tectonic forces related to globalization, technology, and sustainability that require innovative responses from enterprises worldwide and, not least, from Canada.
Accelerating the Take-Up of Climate Change Innovations
Authors: Dale Ann
Published: November 2016

The paper explains the findings of the MC3 Project (Meeting the Climate Change Challenge). This project brought together over 100 researchers, practitioners, civil-society leaders, and policy-makers, led by researchers from Royal Roads University, Simon Fraser University, and the University of British Columbia, with 12 major research partners from the public and private sectors, including the Union of British Columbia municipalities. Researchers conducted a detailed evaluation of 11 leading, yet different, municipalities across the province to identify the leading innovators and innovations on climate action. The case studies revealed the following key drivers of innovation, in order of prominence: the legislative and policy framework, supported by provincially led incentives and tools, access to partnership funding and intermediary support, and framing the issue as critically important.
Antimicrobial Usage and Antimicrobial Resistance in Animal Production in Southeast Asia: A Review
Authors: Nhung Nguyen , Cuong Nguyen , Thwaites Guy , Carrique-Mas Juan
Published: November 2016

Southeast Asia is an area of great economic dynamism. In recent years, it has experienced a rapid rise in the levels of animal product production and consumption. The region is considered to be a hotspot for infectious diseases and antimicrobial resistance (AMR). We reviewed English-language peer-reviewed publications related to antimicrobial usage (AMU) and AMR in animal production, as well as antimicrobial residues in meat and fish from 2000 to 2016, in the region. There is a paucity of data from most countries and for most bacterial pathogens. Most of the published work relates to non-typhoidal Salmonella (NTS), Escherichia coli (E. coli), and Campylobacter spp. (mainly from Vietnam and Thailand), Enterococcus spp. (Malaysia), and methicillin-resistant Staphylococcus aureus (MRSA) (Thailand). However, most studies used the disk diffusion method for antimicrobial susceptibility testing; breakpoints were interpreted using Clinical Standard Laboratory Institute (CSLI) guidelines. Statistical models integrating data from publications on AMR in NTS and E. coli studies show a higher overall prevalence of AMR in pig isolates, and an increase in levels of AMR over the years. AMU studies (mostly from Vietnam) indicate very high usage levels of most types of antimicrobials, including beta-lactams, aminoglycosides, macrolides, and quinolones. This review summarizes information about genetic determinants of resistance, most of which are transferrable (mostly plasmids and integrons). The data in this review provide a benchmark to help focus research and policies on AMU and AMR in the region.
A Novel Flux Focusing Magnetically Geared Machine with Reduced Eddy Current Loss
Authors: Liu Jin , Zhao Wenxiang , Ji Jinghua , Liu Guohai , Tao Tao
Published: November 2016

This paper proposes a novel flux focusing magnetically geared (MG) machine for wind power generation, considering the permanent magnets (PMs) eddy current loss and the balance between the pull-out torque of MG machine and the back-electromotive force (EMF)of the PM brushless machine. The PM eddy current loss in the two rotors of the conventional surface-mounted MG machine is calculated and analyzed by using finite-element method. By adopting serial-spoke structure in the inner rotor, a novel rotor structure for a MG machine is proposed to reduce the PM eddy current loss. Moreover, in order to balance the pull-out torque and the back-EMF, several serial-spoke structures and the main design parameters are investigated. Then, a quantitative comparison between the proposed topology and the conventional surface-mounted MG machine is performed. The analysis results indicate that the PM eddy current loss of the proposed MG machine can be significantly reduced and its pull-out torque and back-EMF can be balanced well.
Basic Characteristics and Design of a Novel Hybrid Magnetic Bearing for Wind Turbines
Authors: Yu Yanjun , Zhang Weiyu , Sun Yuxin , Xu Peifeng
Published: November 2016

This paper proposes a five-degree-of-freedom (5-DOF) hybrid magnetic bearing (HMB) for direct-drive wind turbines, which can realize suspension in the 4-DOF radial and 1-DOF axial directions. Only two sets of radial control windings are employed in the proposed HMB because only one set of radial control windings can achieve the 2-DOF suspension in the radial direction. Unlike the traditional active thrust magnetic bearings, this paper uses a cylindrical rotor core without a large thrust disc in the novel HMB. The numbers of the controller, power amplifier and system volume can be reduced in the magnetic suspension system. This paper also presents the structure and basic characteristics of the proposed magnetic bearing. A precision equivalent magnetic circuit analysis of the permanent magnet ring and control magnetic field is conducted in this study, in consideration of the non-uniform distribution of magnetic density. Accordingly, the mathematical models, including the suspension force expression, are derived based on the accurate equivalent magnetic circuit. The basic principle of the structure parameter design is presented, based on the given key parameters. The accuracy of the analytical method is further validated by 3D finite element analysis.
Physical Conditions and Variability Processes in AGN Jets through Multi-Frequency Linear and Circular Radio Polarization Monitoring
Authors: Myserlis Ioannis , Angelakis Emmanouil , Kraus Alex , Fuhrmann Lars , Karamanavis Vassilis , Zensus J.
Published: November 2016

Radio polarimetry is an invaluable tool to investigate the physical conditions and variability processes in active galactic nuclei (AGN) jets. However, detecting their linear and circular polarization properties is a challenging endeavor due to their low levels and possible depolarization effects. We have developed an end-to-end data analysis methodology to recover the polarization properties of unresolved sources with high accuracy. It has been applied to recover the linear and circular polarization of 87 AGNs measured by the F-GAMMA program from July 2010 to January 2015 with a mean cadence of 1.3 months. Their linear polarization was recovered at four frequencies between 2.64 and 10.45 GHz and the circular polarization at 4.85 and 8.35 GHz. The physical conditions required to reproduce the observed polarization properties and the processes which induce their variability were investigated with a full-Stokes radiative transfer code which emulates the synchrotron emission of modeled jets. The model was used to investigate the conditions needed to reproduce the observed polarization behavior for the blazar 3C 454.3, assuming that the observed variability is attributed to evolving internal shocks propagating downstream.
On the Non-Thermal Energy Content of Cosmic Structures
Authors: Vazza Franco , Wittor Denis , Brüggen Marcus , Gheller Claudio
Published: November 2016

(1) Background: the budget of non-thermal energy in galaxy clusters is not well constrained, owing to the observational and theoretical difficulties in studying these diluted plasmas on large scales; (2) Method: we use recent cosmological simulations with complex physics in order to connect the emergence of non-thermal energy to the underlying evolution of gas and dark matter; (3) Results: the impact of non-thermal energy (e.g., cosmic rays, magnetic fields and turbulent motions) is found to increase in the outer region of galaxy clusters. Within numerical and theoretical uncertainties, turbulent motions dominate the budget of non-thermal energy in most of the cosmic volume; (4) Conclusion: assessing the distribution non-thermal energy in galaxy clusters is crucial to perform high-precision cosmology in the future. Constraining the level of non-thermal energy in cluster outskirts will improve our understanding of the acceleration of relativistic particles and of the origin of extragalactic magnetic fields.
Identifying Spatio-Temporal Landslide Hotspots on North Island, New Zealand, by Analyzing Historical and Recent Aerial Photography
Authors: Hölbling Daniel , Betts Harley , Spiekermann Raphael , Phillips Chris
Published: November 2016

Accurate mapping of landslides and the reliable identification of areas most affected by landslides are essential for advancing the understanding of landslide erosion processes. Remote sensing data provides a valuable source of information on the spatial distribution and location of landslides. In this paper we present an approach for identifying landslide-prone “hotspots” and their spatio-temporal variability by analyzing historical and recent aerial photography from five different dates, ranging from 1944 to 2011, for a study site near the town of Pahiatua, southeastern North Island, New Zealand. Landslide hotspots are identified from the distribution of semi-automatically detected landslides using object-based image analysis (OBIA), and compared to hotspots derived from manually mapped landslides. When comparing the overlapping areas of the semi-automatically and manually mapped landslides the accuracy values of the OBIA results range between 46% and 61% for the producer’s accuracy and between 44% and 77% for the user’s accuracy. When evaluating whether a manually digitized landslide polygon is only intersected to some extent by any semi-automatically mapped landslide, we observe that for the natural-color images the landslide detection rate is 83% for 2011 and 93% for 2005; for the panchromatic images the values are slightly lower (67% for 1997, 74% for 1979, and 72% for 1944). A comparison of the derived landslide hotspot maps shows that the distribution of the manually identified landslides and those mapped with OBIA is very similar for all periods; though the results also reveal that mapping landslide tails generally requires visual interpretation. Information on the spatio-temporal evolution of landslide hotspots can be useful for the development of location-specific, beneficial intervention measures and for assessing landscape dynamics.
Proposal of Environmental Impact Assessment Method for Concrete in South Korea: An Application in LCA (Life Cycle Assessment)
Authors: Kim Tae , Tae Sung
Published: November 2016

This study aims to develop a system for assessing the impact of the substances discharged from concrete production process on six environmental impact categories, i.e., global warming (GWP), acidification (AP), eutrophication (EP), abiotic depletion (ADP), ozone depletion (ODP), and photochemical oxidant creation (POCP), using the life a cycle assessment (LCA) method. To achieve this, this study proposed an LCA method specifically applicable to the Korean concrete industry by adapting the ISO standards to suit the Korean situations. The proposed LCA method involves a system that performs environmental impact assessment on the basis of input information on concrete mix design, transport distance, and energy consumption in a batch plant. The Concrete Lifecycle Assessment System (CLAS) thus developed provides user-friendly support for environmental impact assessment with specialized database for concrete mix materials and energy sources. In the case analysis using the CLAS, among the substances discharged from the production of 24 MPa concrete, those contributing to GWP, AP, EP, ADP, ODP, and POCP were assessed to amount to 309 kg-CO2 eq/m3, 28.7 kg-SO2 eq/m3, 5.21 kg-PO43− eq/m3, 0.000049 kg-CFC11 eq/m3, 34 kg/m3, and 21 kg-Ethylene eq/m3, respectively. Of these six environmental impact categories selected for the LCA in this study, ordinary Portland cement (OPC) was found to contribute most intensely to GWP and POCP, and aggregates, to AP, EP, ODP, and ADP. It was also found that the mix design with increased prop proportion of recycled aggregate was found to contribute to reducing the impact in all other categories.
Positive Solutions for Nonlinear Caputo Type Fractional q-Difference Equations with Integral Boundary Conditions
Authors: Yang Wengui , Qin Yaping
Published: November 2016

In this paper, by applying some well-known fixed point theorems, we investigate the existence of positive solutions for a class of nonlinear Caputo type fractional q-difference equations with integral boundary conditions. Finally, some interesting examples are presented to illustrate the main results.
Biscogniauxone, a New Isopyrrolonaphthoquinone Compound from the Fungus Biscogniauxia mediterranea Isolated from Deep-Sea Sediments
Authors: Wu Bin , Wiese Jutta , Schmaljohann Rolf , Imhoff Johannes
Published: November 2016

The properties and the production of new metabolites from the fungal strain LF657 isolated from the Herodotes Deep (2800 m depth) in the Mediterranean Sea are reported in this study. The new isolate was identified as Biscogniauxia mediterranea based on ITS1-5.8S-ITS2 and 28S rRNA gene sequences. A new isopyrrolonaphthoquinone with inhibitory activity against glycogen synthase kinase (GSK-3β) was isolated from this fungus. This is the first report of this class of compounds from a fungus isolated from a deep-sea sediment, as well as from a Biscogniauxia species.
Current Advances of Tubulin Inhibitors in Nanoparticle Drug Delivery and Vascular Disruption/Angiogenesis
Authors: Banerjee Souvik , Hwang Dong-Jin , Li Wei , Miller Duane
Published: November 2016

Extensive research over the last decade has resulted in a number of highly potent tubulin polymerization inhibitors acting either as microtubule stabilizing agents (MSAs) or microtubule destabilizing agents (MDAs). These inhibitors have potent cytotoxicity against a broad spectrum of human tumor cell lines. In addition to cytotoxicity, a number of these tubulin inhibitors have exhibited abilities to inhibit formation of new blood vessels as well as disrupt existing blood vessels. Tubulin inhibitors as a vascular disrupting agents (VDAs), mainly from the MDA family, induce rapid tumor vessel occlusion and massive tumor necrosis. Thus, tubulin inhibitors have become increasingly popular in the field of tumor vasculature. However, their pharmaceutical application is halted by a number of limitations including poor solubility and toxicity. Thus, recently, there has been considerable interests in the nanoparticle drug delivery of tubulin inhibitors to circumvent those limitations. This article reviews recent advances in nanoparticle based drug delivery for tubulin inhibitors as well as their tumor vasculature disruption properties.
Hyperspectral Reflectance Anisotropy Measurements Using a Pushbroom Spectrometer on an Unmanned Aerial Vehicle—Results for Barley, Winter Wheat, and Potato
Authors: Roosjen Peter , Suomalainen Juha , Bartholomeus Harm , Clevers Jan
Published: November 2016

Reflectance anisotropy is a signal that contains information on the optical and structural properties of a surface and can be studied by performing multi-angular reflectance measurements that are often done using cumbersome goniometric measurements. In this paper we describe an innovative and fast method where we use a hyperspectral pushbroom spectrometer mounted on a multirotor unmanned aerial vehicle (UAV) to perform such multi-angular measurements. By hovering the UAV above a surface while rotating it around its vertical axis, we were able to sample the reflectance anisotropy within the field of view of the spectrometer, covering all view azimuth directions up to a 30° view zenith angle. We used this method to study the reflectance anisotropy of barley, potato, and winter wheat at different growth stages. The reflectance anisotropy patterns of the crops were interpreted by analysis of the parameters obtained by fitting of the Rahman-Pinty-Verstraete (RPV) model at a 5-nm interval in the 450–915 nm range. To demonstrate the results of our method, we firstly present measurements of barley and winter wheat at two different growth stages. On the first measuring day, barley and winter wheat had structurally comparable canopies and displayed similar anisotropic reflectance patterns. On the second measuring day the anisotropy of crops differed significantly due to the crop-specific development of grain heads in the top layer of their canopies. Secondly, we show how the anisotropy is reduced for a potato canopy when it grows from an open row structure to a closed canopy. In this case, especially the backward scattering intensity was strongly diminished due to the decrease in shadowing effects that were caused by the potato rows that were still present on the first measuring day. The results of this study indicate that the presented method is capable of retrieving anisotropic reflectance characteristics of vegetation canopies and that it is a feasible alternative for field goniometer measurements.
Simulation of SAW Humidity Sensors Based on ( 11 2 ¯ 0 ) ZnO/R-Sapphire Structures
Authors: Lan Xiao-Dong , Zhang Shu-Yi , Fan Li , Wang Yan
Published: November 2016

The characteristics of two types of surface acoustic waves SAWs (Rayleigh waves and Love waves) propagating in bilayered structures of ( 11 2 ¯ 0 ) ZnO/R-sapphire are simulated by a finite element method (FEM) model, in which both SAWs have crossed propagation directions. Furthermore, based on the bilayered structures, the frequency responses of Rayleigh wave and Love wave humidity sensors are also simulated. Meanwhile, the frequency shifts, insertion loss changes and then the sensitivities of both humidity sensors induced by the adsorbed water layer perturbations, including the mechanical and electrical factors, are calculated numerically. Generally, the characteristics and performances of both sensors are strongly dependent on the thickness of the ZnO films. By appropriate selecting the ratio of the film thickness to SAW wavelength for each kind of the sensors, the performances of both sensors can be optimized.
Multi-Sensor Fusion with Interaction Multiple Model and Chi-Square Test Tolerant Filter
Authors: Yang Chun , Mohammadi Arash , Chen Qing-Wei
Published: November 2016

Motivated by the key importance of multi-sensor information fusion algorithms in the state-of-the-art integrated navigation systems due to recent advancements in sensor technologies, telecommunication, and navigation systems, the paper proposes an improved and innovative fault-tolerant fusion framework. An integrated navigation system is considered consisting of four sensory sub-systems, i.e., Strap-down Inertial Navigation System (SINS), Global Navigation System (GPS), the Bei-Dou2 (BD2) and Celestial Navigation System (CNS) navigation sensors. In such multi-sensor applications, on the one hand, the design of an efficient fusion methodology is extremely constrained specially when no information regarding the system’s error characteristics is available. On the other hand, the development of an accurate fault detection and integrity monitoring solution is both challenging and critical. The paper addresses the sensitivity issues of conventional fault detection solutions and the unavailability of a precisely known system model by jointly designing fault detection and information fusion algorithms. In particular, by using ideas from Interacting Multiple Model (IMM) filters, the uncertainty of the system will be adjusted adaptively by model probabilities and using the proposed fuzzy-based fusion framework. The paper also addresses the problem of using corrupted measurements for fault detection purposes by designing a two state propagator chi-square test jointly with the fusion algorithm. Two IMM predictors, running in parallel, are used and alternatively reactivated based on the received information form the fusion filter to increase the reliability and accuracy of the proposed detection solution. With the combination of the IMM and the proposed fusion method, we increase the failure sensitivity of the detection system and, thereby, significantly increase the overall reliability and accuracy of the integrated navigation system. Simulation results indicate that the proposed fault tolerant fusion framework provides superior performance over its traditional counterparts.
Feature Mining and Health Assessment for Gearboxes Using Run-Up/Coast-Down Signals
Authors: Zhao Ming , Lin Jing , Miao Yonghao , Xu Xiaoqiang
Published: November 2016

Vibration signals measured in the run-up/coast-down (R/C) processes usually carry rich information about the health status of machinery. However, a major challenge in R/C signals analysis lies in how to exploit more diagnostic information, and how this information could be properly integrated to achieve a more reliable maintenance decision. Aiming at this problem, a framework of R/C signals analysis is presented for the health assessment of gearbox. In the proposed methodology, we first investigate the data preprocessing and feature selection issues for R/C signals. Based on that, a sparsity-guided feature enhancement scheme is then proposed to extract the weak phase jitter associated with gear defect. In order for an effective feature mining and integration under R/C, a generalized phase demodulation technique is further established to reveal the evolution of modulation feature with operating speed and rotation angle. The experimental results indicate that the proposed methodology could not only detect the presence of gear damage, but also offer a novel insight into the dynamic behavior of gearbox.
A Stretchable Radio-Frequency Strain Sensor Using Screen Printing Technology
Authors: Jeong Heijun , Lim Sungjoon
Published: November 2016

In this paper, we propose a stretchable radio-frequency (RF) strain sensor fabricated with screen printing technology. The RF sensor is designed using a half-wavelength patch that resonates at 3.7 GHz. The resonant frequency is determined by the length of the patch, and it therefore changes when the patch is stretched. Polydimethylsiloxane (PDMS) is used to create the substrate, because of its stretchable and screen-printable surface. In addition, Dupont PE872 (Dupont, NC, American) silver conductive ink is used to create the stretchable conductive patterns. The sensor performance is demonstrated both with full-wave simulations and with measurements carried out on a fabricated sample. When the length of the patch sensor is increased by a 7.8% stretch, the resonant frequency decreases from 3.7 GHz to 3.43 GHz, evidencing a sensitivity of 3.43 × 107 Hz/%. Stretching the patch along its width does not change the resonant frequency.
Complex IoT Systems as Enablers for Smart Homes in a Smart City Vision
Authors: Lynggaard Per , Skouby Knud
Published: November 2016

The world is entering a new era, where Internet-of-Things (IoT), smart homes, and smart cities will play an important role in meeting the so-called big challenges. In the near future, it is foreseen that the majority of the world’s population will live their lives in smart homes and in smart cities. To deal with these challenges, to support a sustainable urban development, and to improve the quality of life for citizens, a multi-disciplinary approach is needed. It seems evident, however, that a new, advanced Information and Communications Technology ICT infrastructure is a key feature to realize the “smart” vision. This paper proposes a specific solution in the form of a hierarchical layered ICT based infrastructure that handles ICT issues related to the “big challenges” and seamlessly integrates IoT, smart homes, and smart city structures into one coherent unit. To exemplify benefits of this infrastructure, a complex IoT system has been deployed, simulated and elaborated. This simulation deals with wastewater energy harvesting from smart buildings located in a smart city context. From the simulations, it has been found that the proposed infrastructure is able to harvest between 50% and 75% of the wastewater energy in a smart residential building. By letting the smart city infrastructure coordinate and control the harvest time and duration, it is possible to achieve considerable energy savings in the smart homes, and it is possible to reduce the peak-load for district heating plants.
Optical Microbottle Resonators for Sensing
Authors: Bianucci Pablo
Published: November 2016

Whispering gallery mode (WGM) optical microresonators have been shown to be the basis for sensors able to detect minute changes in their environment. This has made them a well-established platform for highly sensitive physical, chemical, and biological sensors. Microbottle resonators (MBR) are a type of WGM optical microresonator. They share characteristics with other, more established, resonator geometries such as cylinders and spheres, while presenting their unique spectral signature and other distinguishing features. In this review, we discuss recent advances in the theory and fabrication of different kinds of MBRs, including hollow ones, and their application to optofluidic sensing.
In Their Own Words: The Health and Sexuality of Immigrant Women with Infibulation Living in Switzerland
Authors: Villani Michela , Griffin Judith , Bodenmann Patrick
Published: November 2016

Female genital mutilation (FGM) is a significant public health problem. It is estimated that around 14,700 women affected by FGM live in Switzerland, primarily among women with a history of migration. Our qualitative research investigated the sexual health of immigrant women living with FGM in Switzerland, describing their own perception of health, reproductive life and sexuality. We conducted semi-structured, in-depth interviews with a group of eight immigrant women of sub-Saharan origin living in Switzerland with Type III FGM (infibulation). Seven of the women were from Somalia and one was from the Ivory Coast. All of the Somali women were mothers and married (two separated), and the Ivorian woman was a single mother. The women in our study reported a low level of sexual satisfaction and reproductive health. They affirmed their desire to improve, or at least change, their condition. Although they rarely talk with their husbands about sexual subject matter, they would like to include them more and improve dialogue. Specific socio-sexual management is recommended when caring for immigrant women living with FGM in order to respond to their specific health care needs. Multidisciplinary approaches may be able to offer more comprehensive health care, including facilitated communication to improve dialogue between women and health care professionals, and eventually between women and their husbands in discussing sexual subject matter.
Influence of Different Mowing Systems on Community Characteristics and the Compensatory Growth of Important Species of the Stipa grandis Steppe in Inner Mongolia
Authors: Wan Zhiqiang , Yang Jiuyan , Gu Rui , Liang Yan , Yan Yulong , Gao Qingzhu , Yang Jie
Published: November 2016

The Stipa grandis steppe is a type of steppe in the Central Asian sub-region, and it is an important resource for livestock production in China. Mowing is one of the main management methods for this steppe. Verifying the response of the Stipa grandis steppe communities to different mowing frequencies is essential for the rational utilization of pastures and the protection and recovery of natural steppe. In this study, we investigated the community characteristics and compensatory growth of important species of the Stipa grandis steppe community under four mowing frequencies (TAY: twice a year; OAY: once a year; OTY: once every other year; NM: no mowing/enclosure), and found that different frequencies of mowing significantly influenced the community characteristics and the compensatory growth of dominant plant species. In the enclosure, species density was significantly lower, and height and biomass were significantly greater than in the mowing treatments. At the beginning of the growing season, mowing had a significant impact on the individual miniaturization of Stipa grandis, Leymus chinensis, and Anemarrhena asphodeloides. Mowing also had a significant impact on the diversity of the community. The Shannon diversity index, the Pielou evenness index, and the richness index were higher under OTY than other mowing frequencies. Under different mowing frequencies, growth rates were significantly different after the aboveground portions were cut, while the levels of biomass were not significantly different. Stipa grandis, Leymus chinensis, and Anemarrhena asphodeloides had less compensatory height growth under OAY compared to the other treatments; however, there were no significant differences in the relative growth rates of the three species under different treatments. Stipa grandis exhibited equivalent compensatory height growth; both Leymus chinensis and Anemarrhena asphodeloides exhibited over-compensatory growth. Based on the results of community characteristics and the compensatory growth of the dominant species, mowing every other year is currently the most practical mowing system.
Potentials and Limitations of Regional Organic Food Supply: A Qualitative Analysis of Two Food Chain Types in the Berlin Metropolitan Region
Authors: Doernberg Alexandra , Zasada Ingo , Bruszewska Katarzyna , Skoczowski Björn , Piorr Annette
Published: November 2016

Regional food systems and organic agriculture are both considered more sustainable than the conventional, globalized food system they provide an alternative to. The emergence and expansion of alternative forms of food supply are influenced by various factors on different scales. Using the food systems approach we aim to study potentials and limitations of regional organic food supply in the Berlin metropolitan region (BMR). Based on the literature, we developed an analytical framework and identified determinants of regional organic food provision along the three major levels of the supply chain: agricultural production, food chain organization, and consumption. Then, we examined a qualitative case study with two different types of alternative food networks (A) organic community supported agriculture (CSA) and (B) organic retail trade. Factors that hinder or promote the provision of regional organic food were identified through qualitative interviews and assessed by regional stakeholders in a workshop. Our findings show that demand for regional organic food is higher than regional supply, which could offer good possibilities for organic farmers. However, actors in these two food chains need to overcome some obstacles, including limited access to land, increasing renting prices, insufficient processing capacities, and unsupportive political environment for organic farming.