bluuebunny/crossref_metadata_2025 huggingface dataset:
Censos 2017: Existe Número Suficiente de Anestesiologistas em Portugal?
Authors: Lemos Paulo , Guedes Alexandra , Mourão Joana , Lima Joaquim Figueiredo , Veiga José , Chedas Manuel , Branca Pedro , Abrunhosa Rosário , Cadilha Susana , Almeida Valentina
Published: June 2018

Introdução: O objectivo deste estudo é identificar o número de anestesiologistas e monitorizar a actividade da Anestesiologia em Portugal, comparando-a com idêntico Censos realizado em 2014.Material e Métodos: Estudo observacional transversal. Foram contactados, em maio de 2017, os diretores dos serviços de Anestesiologia das instituições hospitalares com actividade cirúrgica que compõem o Serviço Nacional de Saúde, num total de 53 instituições hospitalares, correspondendo a 86 hospitais.Resultados: O Censos registou um total de 615 127 intervenções cirúrgicas (mais 3,4% que em 2013), das quais 84,1% foram cirurgias programadas e destas 49,6% em regime de ambulatório (mais 6,1% que em 2013). Constatou-se ainda a realização de 89 608 procedimentos com apoio de anestesia fora do bloco operatório (menos 19,0% que em 2013), 282 944 consultas de anestesia (mais 1,3% que em 2013) e 112 183 consultas de dor crónica (mais 13,1% que em 2013). Identificaram-se 51 380 analgesias de parto (mais 14,3% que em 2013), que corresponderam a 70,5% dos partos ocorridos nos serviços de Obstetrícia dos hospitais do Serviço Nacional de Saúde (mais 5% de partos que em 2013). Foram identificados 1280 Anestesiologistas (mais 2,1% do que em maio de 2014), o que corresponde a um rácio de 12,4 por 100 000 habitantes (este valor era de 12,0 em maio de 2014). Com os 262 Anestesiologistas a trabalhar exclusivamente no sector privado, obtém-se um total nacional de 1542 Anestesiologistas, ou seja, um rácio de 15,1 por 100 000 habitantes (este valor era 13,9 em maio de 2014).Discussão: Prevê-se que o déficit de 541 Anestesiologistas identificados, possa ser reduzido em cerca de dois terços até 2023. A redução do déficit de Anestesiologistas permitirá aumentar a capacidade de resposta às crescentes solicitações dos serviços de anestesiologia Portugueses.Conclusão: Apesar de um ligeiro aumento do rácio de anestesiologistas por habitante em 2017 comparativamente a 2014, Portugal continua com um déficit de Anestesiologistas.
Extragenital Gonorrhoea in Men Who Have Sex with Men: A Retrospective Study in a STI Clinic in Lisbon, Portugal
Authors: Valejo Coelho Margarida Moura , Matos-Pires Eugénia , Serrão Vasco , Rodrigues Ana , Fernandes Cândida
Published: June 2018

Introduction: Recent studies worldwide reveal a significant prevalence of extragenital infections by Neisseria gonorrhoeae among men who have sex with men. We aimed to analyse the frequency and characteristics of extragenital gonococcal infections diagnosed in men who have sex with men in a walk-in Sexually Transmitted Infection clinic in Lisbon, Portugal.Material and Methods: We conducted a cross-sectional, retrospective study of the anorectal and/or oropharyngeal Neisseria gonorrhoeae infections in men who have sex with men, diagnosed in our Sexually Transmitted Infection clinic between January 2014 and December 2016.Results: We found extragenital infection in 87 cases of gonorrhoea identified in men who have sex with men in this period, including: 49 cases of anorectal disease, 9 of oropharyngeal disease, 13 cases of infection at both extragenital sites, and 16 of simultaneous extragenital and urogenital gonorrhoea. Patients’ ages ranged from 17 to 64 years (median: 28 years). Forty-seven (54%) of the patients did not present with any extragenital symptoms. Thirty (35%) were human immunodeficiency virus-1-positive.Discussion: Since most extragenital Neisseria gonorrhoeae infections are asymptomatic, they may be missed and go untreated unless actively investigated. Current international guidelines recommend the screening of gonorrhoea at extragenital sites in men who have sex with men because anorectal and oropharyngeal infections constitute a potential disease reservoir, and may facilitate transmission and/or acquisition of human immunodeficiency virus infection.Conclusion: Our results highlight the relevance of testing men who have sex with men for Neisseria gonorrhoeae at extragenital sites, regardless of the existence of local complaints. The implementation of adequate screening programmes in Portugal should be considered. We also reinforce the need to raise awareness in the population regarding the adoption of prophylactic measures against transmission of sexually transmitted infections during anal and/or oral sexual exposure.
O Impacto das Alterações Climáticas na Saúde
Authors: Tavares António
Published: June 2018

N/A.
Sobre o Significado da Significância Estatística
Authors: Teixeira Pedro Miguel
Published: June 2018

N/A.
Reaching Mental Health Research Participants with Multiple Stigmas; A Description of Strategies Used in a Depression Intervention Study for YMSM of Color with HIV
Authors: Houston Eric , Argueta Chris , Lacey Jahmil , Mukherjee Sukrit , Breda-Hill Kieran
Published: June 2018

Research indicates that stigma serves as a barrier to the recruitment of participants into mental health intervention studies. Some participants, such as those for depression intervention studies that target people with human immunodeficiency virus (HIV), may face multiple sources of stigma. The purpose of this brief report was to describe recruitment strategies used during the initial months of an ongoing preliminary pilot study designed to develop a web-based intervention for young African American and Latino gay and bisexual men living with HIV who reported symptoms of depression. We employed four primary recruitment strategies to identify potential participants in the Los Angeles metropolitan area for the study. These strategies included social media, referrals, direct contact, and recruitment flyers. Preliminary data indicated that recruitment efforts generated 57 responses from potential participants during the first four months of recruitment and study implementation. The monthly response rate from potential participants represented slightly more than 71% of the study’s minimum level targeted for participant enrollment. Findings from this preliminary study are discussed in terms of the role of stigma as a barrier to mental health participant research recruitment. Implications for both depression research and clinical interventions are considered.
Mercury behaviour in flue gas from sewage sludge incinerators and melting furnace
Authors: Takaoka Masaki , Oshita Kazuyuki , Okada Masaharu , Watanabe Tomoaki , Tanida Koji
Published: June 2018

Thermal conversion of sewage sludge can be a clean source of renewable energy if the emission of air pollutants from the source is controlled. In 2013, the Minamata Convention on Mercury was adopted, placing greater emphasis on the control of mercury emissions, including mercury emissions from sewage sludge incinerators. To characterise the behaviour of mercury in flue gas, particulate and gaseous mercury concentrations in two incinerators and a melting furnace were measured by manual sampling. In a third facility, continuous emission monitoring was used to characterise temporal trends in gaseous mercury concentrations. Wet scrubbers were determined to be effective air pollution control devices suitable for mercury removal. Stack mercury concentrations were found to be <10 μg/Nm3, which meets the mercury emission standard for existing plants (50 μg/Nm3).
Innovations in the brazilian offshore support vessel chain: a content analysis approach
Authors: Queiroz Maciel , Telles Renato , Hamaji Edison Yoshihiro
Published: June 2018

This work discusses innovation in a traditional oil chain industry in Brazil, the offshore support vessel. To sustainably increase production, innovation is a mandatory strategy. This paper approaches the Brazilian offshore support vessel industry from an innovation perspective by a content analysis method and thus provides several contributions from both academic and managerial perspectives. From academic standpoint, there are several unanswered questions and vast research opportunities, such as improvements in academic-firm relationships to enhance knowledge sharing and contributions to the literature. From a managerial perspective, this study reflects on maturity level of companiesâ€™ innovation and the needs of developing explicit strategies to achieve better innovation results.
Fasciola Hepatica Extract Induces Cell Death of Mammalian Cells
Authors: Ferreira Stephanie , Fernandes Ruben , C. Botelho Monica
Published: June 2018

Background: Fascioliasis is a neglected tropical disease that affects poor people from poor
and developing countries. In the world, it has been estimated that at least 2.6 million people are affected
with this disease. The International agency for Research on Cancer, states that O. viverrini and C. sinensis,
also liver flukes, are considered as definitive causes of cholangiocarcinoma. However, fascioliasis
caused by F. hepatica has not been associated with cancer to date. There are not any known causative
associations between this parasite and liver cancer (cholangiocarcinoma).

Methods: Chine Hamster Ovary (CHO) cells were treated with F. haepatica extracts and cell proliferation
was assessed by using the indirect method for estimating cell number based on the mitochondrial
activity with MTS cell proliferation reagent. We observed unexpected death of these cells when treated
with F. haepatica extracts.

Results and Conclusion: We now hypothesize that this parasite could be used as a medically-important
trematode pathogen in cancer therapy.
Efficient Removal of Lead and Cadmium ions by Titanate Nanotubes Prepared at Different Hydrothermal Conditions
Authors: Alwaili Maha A. , Elbaghdady Heba Allah M. , Zaki Ayman H. , Sallam Mohammed A.
Published: June 2018

Background:

Nanotubes serve an important role in heavy metal ions for the removal from
wastewater. The efficiency of these nanotubes is dependent on the nature of surface, pH, temperature
setting and the hydrothermal contact time.

Method:

The current research sought to find out the efficiency of titanate nanotubes in the removal
of Pb2+ and Cd2+ ions from wastewater. The research concentrated on mesoporosity, pH and hydrothermal
contact time, as factors affecting the efficiency of titanate nanotubes in the removal of Pb2+
and Cd2+ ions. Titanate nanotubes were prepared at different hydrothermal conditions, the prepared
nanotubes were used for efficient removal of Pb2+ and Cd2+. The following technologies were utilized
in the research: (1). electron microscopy (FESEM), (2). X-ray diffraction (XRD), (3). highresolution
transmission electron microscopy (HRTEM), (4). FTIR and BET surface area were measured
by N2 adsorption using Micrometrics TriStar II.

Results:

The results obtained reveal that increasing the hydrothermal time improved the adsorption
efficiency of the prepared material, where the Titanate nanotubes prepared at the longest time (23hr)
achieved the highest removal efficiency for both Pb2+ and Cd2+ at pH 2 and pH 3, respectively. The
nanotubes prepared at different conditions also showed significant activities, where the removal %
exceeded 90 % for all samples at a pH range of 2 to 3.

Conclusion:

It was conducted that the factors that affected the efficiency could be set at optimum
and the removal efficiency attained be increased, to more than 90%.
Fuzzy PID Sliding Mode Control for Robotics: An Application to Surgical Robot
Authors: Qureshi Mohd S. , Swarnkar Pankaj , Gupta Sushma
Published: June 2018

Background:

Continually in view of the fact that digital technology entered in the Operating
Theatre (OT), surgery has moved out through one of the big revolutions in medical field. Robotic-Assisted
Surgery (RAS) is a way of technological development in the medical environment, designed to thrash the
limitations of Minimal Invasive Surgery (MIS). Surgical robots carry out operation with the motion control
of manipulator joints on the patient. Precise and fine control of these robots is very imperative.

Methods:

The paper depicts the control methodology for surgical robots based on the combination of Sliding
Mode Control (SMC) with Fuzzy Logic Control (FLC). The destructive chattering phenomenon in
SMC is circumvented by espousing FLC in SMC. System stability is investigated using Lyapunov theorem.
All numerical simulations have been carried out using MATLAB tool for 2 DOF robot manipulator
formulated for trajectory tracking process which shows the efficacy of the proposed methodology.

Results:

The simulation results of FSMC are compared with the conventional SMC which represents
the improvement of control law for the attainment of optimized results.

Conclusion:

The proposed methodology in the paper is very much suitable in controlling surgical robot
during typical surgical operations. The effectiveness of proposed control methodology is shown using
simulation studies in the paper.
A ontologia da singularidade e a educação em Hannah Arendt: Uma preparação para o mundo
Authors: Briskievicz Danilo Arnaldo
Published: June 2018

Investigamos no pensamento de Hannah Arendt a possibilidade de uma ontologia da singularidade relacionada diretamente com a educação, como protomomento da ontologia da pluralidade, iniciada com o nascimento e ampliada pela chegada ao mundo comum, ao espaço da ação. Destacamos alguns pontos de sua teoria política, inter-relacionando-os com apontamentos sobre a educação do texto A Crise da Educação, de 1958. Apresentamos a educação como espaço privilegiado de formação da vida do espírito, essencial, por ser inicial, em tempo e espaço para o exercício pleno da vita activa. A ontologia da singularidade é fundamentada a partir de seis pontos em que é preciso: acolher, preparar e incluir os singulares; fomentar espaços para o discursar, valorizar as diferenças e preservar a tradição. Apresentamos dois antimodelos para a ontologia da singularidade: na educação escolar, os campos de concentração, pela prerrogativa do uso da violência e da mudez; para os educandos, Adolf Eichmann, por causa de seu vazio de pensamento e incapacidade de agir criativamente no mundo. Propomos que a duração da educação é proporcional à criatividade narracional da tradição pela autoridade dos professores.Palavras-chave: Hannah Arendt; Ontologia da singularidade; Filosofia da educação; Vida do espírito ABSTRACTWe investigate in Hannah Arendt's thinking the possibility of an ontology of singularity directly related to education, as protomoment of the ontology of plurality, initiated with the birth and enlarged by the arrival to the common world, to the space of action. We highlight some points of her political theory interrelating them with notes on education of the text The Crisis of Education, 1958. We present education as a privileged space of formation of the life of the mind, essential, for being initial, in time and space for the full exercise of the vita activa. The ontology of the singularity is based on six points in which it is necessary: to welcome, to prepare and to include the singular ones; to create spaces to promote discourse, to value differences, and to preserve tradition. We present two antimodels for the ontology of singularity: in school education, the concentration camps, by the prerogative of the use of violence and dumbness; for the pupils, Adolf Eichmann, due to  his emptiness of thought and incapacity to act creatively in the world. We propose that the duration of education is proportional to the narrative creativity of tradition by the authority of teachers.Keywords: Hannah Arendt; Ontology of singularity; Philosophy of education; Life of the spirit
O autoconceito de estudantes de ensino médio e sua relação com desempenho acadêmico: Uma revisão sistemática
Authors: Gasparotto Guilherme Da Silva , Szeremeta Thaynara Do Prado , Vagetti Gislaine Cristina , Stoltz Tania , Oliveira Valdomiro De
Published: June 2018

O objetivo do estudo foi revisar sistematicamente as pesquisas que analisaram a relação do autoconceito com o rendimento acadêmico de adolescentes do ensino médio, bem como verificar quais variáveis e contextos dentro da escola foram abordados em conjunto ao autoconceito, para melhor explicar essa relação. A revisão incluiu estudos publicados nos últimos 10 anos nas bases eletrônicas de trabalhos científicos: ERIC/Thesaurus, MEDLINE/Pubmed, SportDiscus, SciELO e Web of Science. Foram utilizados os descritores caracterizando componentes do autoconceito (self, self-concept e self-psychology) com os descritores relacionados ao rendimento acadêmico, em que também se considerou a capacidade acadêmica percebida (academic achievement, underachievement, educational achievement, perception of competence, competence perception, self-efficacy). Dez estudos foram incluídos na revisão. A relação entre autoconceito e desempenho acadêmico mostrou-se consistente e se confirmou em nove dos 10 trabalhos. Outras variáveis também se apresentaram importantes na explicação do desfecho do rendimento acadêmico, tais como a motivação acadêmica, a prática de atividades extracurriculares, a autoeficácia acadêmica e o envolvimento dos pais.Palavras-chave:Estudantes; Psicologia do self; Adolescente; Avaliação do rendimento ABSTRACTThe aim of the study was to systematically review the studies that analyzed the relationship between self-concept and academic achievement in high school students, as well as to verify which variables and contexts within the school were approached together with self-concept, to better explain this relationship. The review included studies published in the last ten years in the scientific electronic databases: ERIC/Thesaurus, MEDLINE/Pubmed, SportDiscus, SciELO and Web of Science. The descriptors that characterized the components of self-concept used were those of self, self-concept and self-psychology, and the descriptors related to academic achievement, academic achievement, underachievement, educational achievement, perception of competence, competence perception and self-efficacy. Ten studies were included in the review. The relationship between self-concept and academic performance was consistent and confirmed in nine of the ten papers. Other variables that were important in explaining the academic achievement were academic motivation, the practice of extracurricular activities, academic self-efficacy and parental involvement.Keywords:Students; Self-psychology; Adolescent; Performance assessment
Disease Burden on Health Facilities in Governorates South of Karbala During the Arbaeenia Mass Gathering in Iraq in 2014: Cross-Sectional Study (Preprint)
Authors: Hantoosh Hayder , Lami Faris , Saber Basel
Published: June 2018

BACKGROUND

Millions of Iraqi pilgrims travel annually from the southern governorates to Karbala and pass through Thiqar, Muthana, and Diwania Governorates to join the Arbaeenia mass gathering event. During this event, participants are at high risk for diseases and death and stifle local health care resources. In addition, the mass gathering causes considerable burden on health facilities in the hosting localities.

OBJECTIVE

This study aims to estimate the disease burden on health facilities caused by the pilgrims passing through Thiqar, Muthana, and Diwania Governorates en route to Karbala in Iraq.

METHODS

This cross-sectional study was conducted on all health facilities in three governorates (Thiqar, Muthana, and Diwania) situated along the southern way to Karbala from Basra. The study started on December 11, 2014, and ended on December 24, 2014. The morbidity and mortality were collected from surveillance logbooks and death registers. Drug purchase data were obtained from the personnel in charge of the pharmacies. The study period was divided into three phases on the basis of the timing of the mass gathering event: pre-event, the event, and postevent.

RESULTS

There were 884,834 incidents reported during the study. The majority of incidents were reported during the event phase (95%) and were attended mostly at mobile clinics (77%). The average daily incidents during the pre-event, event, and postevent phases were 4300, 56,040, and 4548 incidents, respectively. Musculoskeletal disorders were the most common illness reported (55%). The average number of daily deaths was 43, 36, and 45 during the pre-event, event, and postevent, respectively, and these values did not differ significantly. Cardiovascular diseases (43.5%), injuries (29.8%), and respiratory illnesses (12%) were the leading causes of deaths. Approximately US $1.3 million was spent on drug purchases during this mass gathering in the three governorates.

CONCLUSIONS

The Arbaeenia mass gathering causes a tremendous disease and economic burden on governorates that pilgrims pass through to attend this mass gathering in Karbala. Although Iraq’s Ministry of Health is aware of the high burden of this mass gathering on the health facilities in these governorates, more work is needed to ensure quality services during the event.
Analysis of Product and Temperature of Biogas Combustion in Various Air Biogas Equivalence Ratio and Methane Content
Authors: Wresta Arini , Saepudin Aep
Published: June 2018

Biogas resulted from anaerobic digestion of organic compounds have various methane content depend on the type of the degraded material. The methane content of biogas is range between 40–80% that influence the heating value and combustion characteristic of that biogas. The higher methane content can be obtained through upgrading biogas by removing CO2 and other trace components like H2S, NH3, and water vapor. This research was a simulation of product composition and temperature of biogas combustion in various methane content and air biogas equivalence ratio. Biogas combustion was done in combustion chamber at constant pressure of 1 atm. Biogas and air enter into combustion chamber at temperature approximately of 30 °C as the common ambient temperature in Indonesia. The input air was designed higher than stoichiometric need in order to reach complete combustion. Combustion reaction between methane and O2 then carried out in the combustion chamber to produce CO2 and H2O. The product gases consisting of CO2, H2O, N2, and excess O2, bring heat from combustion reaction and exit from combustion chamber at the higher temperature. The analysis was done for methane content range between 20 and 100% with air biogas equivalence ratio from 1 until 3. The simulation result showed that for V m3 biogas, the combustion gases could reach 0.12271 until 1.26798V gmol with temperature above 700 °C until above 1900 °C. More than 50% component in the combustion gases is N2 as inert material from input air to combustion chamber.
Extraction of Alumina from Red Mud for Synthesis of Mesoporous Alumina by Adding CTABr as Mesoporous Directing Agent
Authors: Ramdhani Eka Putra , Wahyuni Tri , Ni’mah Yatim Lailun , Suprapto Suprapto , Prasetyoko Didik
Published: June 2018

Mines in Bintan were producing bauxite for many years. The production process of bauxite to alumina produced much red mud. From X-ray Fluorescence (XRF), alumina content on Bintan’s red mud was 28.87 wt.%. This research was studying on the extraction alumina from red mud with reduction of hematite (Fe2O3) and desilication processes. After extraction process alumina was collected about 52.89 wt.%. Synthesis of mesoporous alumina from red mud using sol-gel method at the room temperature for 72 h with cetyltrimethylammonium bromide (CTABr) as mesoporous directing agent. The CTABr/Al-salt ratio, i.e. 1.57; 4.71 and 7.85 with the sample code of AMC-1, AMC-3, AMC-5, respectively. The product was calcined at 550 °C for 6 h. The synthesized materials were characterized by X-ray Diffraction (XRD), scanning electron microscopy-energy dispersive X-ray (SEM-EDX), transmission electron microscopy (TEM), and N2 adsorption-desorption techniques. XRD pattern of AMC-1, AMC-3, and AMC-5 showed that all synthesized materials have amorphous phase. The morphology were wormhole aggregate that were showed by SEM and TEM characterization. N2 adsorption-desorption characterization showed the distribution of pore size of about 3.2 nm. The highest surface area and pore volume were obtained in solid-solid ratio CTABr/GM-AL by 1.57 (AMC-1) i.e. 241 m2/g and 0.107 cm3/g, respectively.
Synthesis and Characterization of Nanocomposites Tin Oxide-Graphene Doping Pd Using Polyol Method
Authors: Debataraja Aminuddin , Manurung Robeth Viktoria , Asri Lia A.T.W. , Yuliarto Brian , Nugraha Nugraha , Sunendar Bambang
Published: June 2018

This paper report on polyol method for Pd doped tin oxide-graphene nanocomposite thin film. XRD result shows sharp peaks at certain 2θ value and match with tin oxide, graphene, and Pd database. FTIR result shows peak from alcohol chain for –OH strong bonded absorption (3444 cm-1), also there are aldehyde and ketone which are indicated by C=O strong absorption (1751 cm-1). Moreover, alkene is also formed for decreasing symmetry intensity C=C (1616 cm-1), while alkyne is formed at strong deformation absorption at 646 and 613 cm-1. SEM and TEM result show SnO2 particles are attached uniformly on graphene surface layer. The composition for C, O, Sn, and Pd are 33.13, 25.58, 35.35 and 5.94%, respectively. This result indicated that the good composition is formed for Pd doped SnO2-graphene nanocomposite. The nanocomposite is promising materials for toxic gas sensor application at low temperature.
Residue Oil Desulfurization Using Oxidation and Extraction Method
Authors: Tetrisyanda Rizky , Wiguno Annas , Ginting Rizqy Romadhona , Dzikrillah M. Chadiq , Wibawa Gede
Published: June 2018

This study successfully improved the performance of oxidative desulfurization method to reduce sulfur content from residue oil (condensate) with modifications of oxidation and extraction steps which was repeated for several stages. Residue oil used in this study contain 386.2 ppm of initial sulfur content. In oxidation process, H2O2 as oxidizer and acid as catalyst were used within temperature range of 30–60 °C and time interval from 30 to 120 min. In extraction process, various alcohol solvents (methanol, ethanol, and propanol) were used with the temperature of 30 °C in 30 min for every residue oil ratio to solvent (v/v). The best reducing sulfur result achieved was 35.9 ppm or 90.7% desulfurization. This result was achieved after 4 recursively extractions using ethanol as solvent. This study successfully reduced sulfur content in residue oil to meet the international standard (< 50 ppm).
SOCIODEMOGRAPHIC PROFILE OF PATIENTS WITH ACUTE POISONING IN THE EMERGENCY WARDS OF A TERTIARY CARE HOSPITAL
Authors: Reddy Sathvika , Revathi Devi , Prasanna V. Lakshmi , Ramesh Aruna C.
Published: June 2018

Objective: To assess the socio-demographic profile and outcomes in the patients with poisoning admitted to the emergency wards of a tertiary care hospital.Methods: The prospective observational study was conducted for a period of six months in the emergency wards of a tertiary care hospital. The demographic data, hospital admission variables and outcomes were collected from various sources and documented. Cluster analysis was used to find the interaction between the socio-demographic and hospital admission variables in association with outcomes of poisoning.Results: A total of 133 patients were admitted with acute poisoning. The mean age was 27.76±15.5%. Females (51.1%) were dominant over males (48.8%). Incidents of poisoning were predominant in married (49.6%), literates (41.35%), abiding in urban region (86.4%) and belonging to upper lower class (37.6%). The poisonings were intentional (69.17%) occurring through oral route (81.2%) at home (82%). Reason for poisoning was the most significant (1.00*) predictor followed by route of poisoning. Patients with mild symptoms were 85.71% 10.5% moderate and severe symptoms 3.75%. Majority of the victims recovered (82.71%) whilst 4.51% died.Conclusion: Poisoning patterns vary with socio-demographic and socio-economic status, which is a prevalent social and economic issue in developing countries. Depression acts as a slow poison and is common among younger age groups leading to increased cases of intentional poisoning, thereby indicating a necessity for appropriate psychiatric counselling, medical and peer management strategies to identify the individuals in need that can reduce the risk of next attempt.
INVESTIGATING THE POTENTIAL OF AN ANTIDEPRESSANT INTRANASAL MUCOADHESIVE MICROEMULSION
Authors: Singh Gurpreet , Rawat Nisha , Singh Kirti , Sarwal Amita , Sinha V. R.
Published: June 2018

Objective: The main aim of this study was to formulate, develop and optimized a duloxetine hydrochloride (dlx-hcl) loaded mucoadhesive microemulsion intended for intranasal administration.Methods: Established on solubility studies capmul mcm, transcutol-p, labrasol were used as oil, co-surfactant and surfactant respectively. The optimized mucoadhesive microemulsion prepared using water titration method was further characterized for particle size, polydispersity index, zeta potential and conductivity measurements followed by drug content, nasal cilio toxicity and biochemical estimation of the selected formulation.Results: All physicochemical parameters conducted, proved that dlx-hcl microemulsion was appropriate for nasal delivery. Chitosan, used as mucoadhesive polymer demonstrated enhanced retention time of the microemulsion in nasal mucosa with no signs of toxicity and epithelial damage. The particle size and zeta potential were found to be of 200 nm and-15 mV respectively considering the formulation safe for nasal delivery.Conclusion: This formulation strategy can be used as an effective targeting technique for the drugs having low bioavailability and poor brain penetration along with an effective method for the treatment long-term disease like depression.
HYDROALCOHOLIC EXTRACTION OF SHOOT CULTURES FROM NOTHAPODYTE NIMMONIANA AND ITS ANTI-PROLIFERATIVE ANALYSIS
Authors: Sharma Arun , Rajata Ankita , Malairaman Udayabanu , Sood Hemant
Published: June 2018

Objective: The important restraints in plant-derived medicine are the convenience of active composites which depends on diverse topographical situations, active compound build-up pattern, environmental circumstances and genetic makeup of the plant. The presented work was aimed to describe an efficient technique for fast propagation of Nothapodytes nimmoniana which is an imperative source of Camptothecin.Methods: Multiple shoots were successfully regenerated from the explants N. nimmoniana using Murashige and Skoog (MS) medium accompanied with IBA+KN+GA3 (1:3:2) mg/l. the hydro-alcoholic extract was obtained by soxhlet extraction for field grown roots (fgRE), shoots (fgSE) and in vitro plantlets (ivPL) and further subjected to phytochemicals analysis. HPLC analysis was performed to determine the percentage of camptothecin (CAM). Anti-proliferative studies were carried out followed by Acridine orange/Ethidium bromide staining. Extracts were also estimated for reactive nitrogen species (RNS) and reactive oxygen species (ROS).Results: Preliminary qualitative chemical analysis of the extracts displayed the presence of alkaloids, carbohydrates, steroids, saponins, terpenoids and phenolics compounds. HPLC analysis revealed the presence of CAM in all the extracts. ivPL exhibited lowest anti-proliferative activity in contrast to other extract and percentage of ROS and RNS was also less. Although ivPL did not exhibited prominent anti-tumour effect, but in vitro accumulation of CAM in 2-months old shoots provides an alternative resource to 5 y-old field grown plants.Conclusion: This work delivers a potential to lead to further increase the potency of CAM in in vitro shoots of two months old as an alternative to the field grown plants for treating cancers.
Comparison of EQ-5D and SF-36 in untreated patients with symptoms of intermittent claudication
Authors: Vaidya Anil , Kleinegris Marie-Claire , Severens Johan L , Ramaekers Bram L , ten Cate-Hoek Arina J , ten Cate Hugo , Joore Manuela A
Published: June 2018

Aim:To compare health-related quality of life (HRQoL) descriptions and utility scores in newly diagnosed peripheral arterial disease (PAD) patients, using two most widely used instruments, EuroQol 5D (EQ-5D) and Medical Outcome Study 36-item Short-Form Health Status Survey (SF-36).Methods:Patients’ self-assessment of HRQoL was measured by the Dutch versions of the EQ-5D and SF-36 in the 204 patients.Results:Mean utility scores ranged from 0.675 for Short-Form Six-Dimension, 0.648 for the EQ-5D UK tariff and 0.715 for the Dutch EQ-5D tariff. A moderate correlation between the utility scores was found due to different valuation techniques of these instruments.Conclusion:Both instruments have clinical validity for use in the PAD and can be used alongside each other to provide a holistic assessment of the HRQoL. Before using these two instruments interchangeably for utility score calculations and healthcare resource allocation, a thorough sensitivity analysis is necessary to explore the robustness of the value argument based on these utility scores.
Gasto público, índice de competitividad y política social en México
Authors: Sánchez-Juárez Isaac
Published: June 2018

Para la realización de este artículo se usó el Índice de Competitividad Social (ICS) construido por el Programa de las Naciones Unidas para el Desarrollo (PNUD-México), para analizar los avances y/o retrocesos en los temas de salud, educación e ingreso laboral de las 32 entidades federativas de la República mexicana en el periodo de 2005-2014. Además, se evaluó mediante técnicas basadas en panel de datos la relación existente entre el ICS y el gasto público. Hallándose que el gasto público en materia social mantuvo una relación negativa con el ICS (la elasticidad fue -0.5764%). Asociado a lo anterior, se demostró que prevaleció la incompetencia social junto al crecimiento del gasto público, por lo que se concluyó que la política social presentó fallas que se sumaron a una política económica que favoreció el bajo crecimiento de la producción.

 
Zonas Económicas Especiales y su impacto sobre el desarrollo económico regional
Authors: Gómez Zaldivar Fernando , Molina Edmundo
Published: June 2018

En el presente artículo se realiza una revisión sistemática de la literatura internacional
relacionada con el impacto que ha tenido el modelo Zonas Económicas Especiales (zee) sobre el desarrollo económico regional. Mediante la identificación, evaluación crítica e integración de los estudios más relevantes y de alta calidad en el tema, se identifican las condiciones básicas de éxito y fracaso de la implementación de este modelo de política industrial, y se discuten los principales resultados considerando las características de los estados en los que se implementarán en México.
Diagnosis and Management of Essential Thrombocythemia in Sanjiwani Hospital Gianyar, Bali: A Case Report
Authors: Wardani Ni Wayan Sri , Putra I Ketut Ery Purnama Warsana , Rena Ni Made Renni A
Published: June 2018

Abstract.

Essential thrombocythemia (ET) is a very rare disorder with 1- /100,000 population in the world. The incidence of this abnormality is still obscure in Indonesia. We report a case of ET, women of age 74 years old that came to Sanjiwani Hospital with gum bleeding. This case is confirmed based on WHO criteria of ET which are the increasing of thrombocyte of a number of increase >450 /µL3, proliferation of megakaryocyte cell on bone marrow biopsy, also not meeting any other WHO criteria for also not meeting any other WHO criteria for BCR-ABL1+CML, Polycythemia Vera, Chronic Myeloid Leukemia, Myelodysplastic Syndrome, or other myeloid neoplasm diseases. Management of this case is based on risk adapted treatment algorithm considering three major risk factors for thrombosis (history of thrombosis, JAK2/MPL mutations, and advanced age). This case is categorized as high risk patient for thrombosis, so that treated with antiplatelet aggregation (aspilets) and anagrelide after hydroxyurea clinically unresponsive.
Computational benchmark for fuel assembly of VVER-1000 using the Monte Carlo Serpent code
Authors: Galchenko Vitaliy , Shlapak Ihor , Gulik Volodymyr
Published: June 2018

The use of a new Monte Carlo Serpent code for the calculation of water-cooled
reactors is presented and a calculation scheme of the fuel assembly for
VVER-1000 reactors developed. The calculation of neutron-physical
characteristics for the fuel assembly of VVER-1000 is carried out for
different states and the results obtained by the Serpent model compared with
the results of other reactor codes. The analyses of these results are
presented in the paper submitted here. Based on this article, the Monte
Carlo Serpent code could be used for neutron-physical calculations of
VVER-1000 reactors.
Evaluation of technological radiation sources in the pumping station of the primary circulation loop and on the top of the pool type research reactor
Authors: Kadalev Stoyan
Published: June 2018

The present paper considers the approach to an assessment of technological
radiation sources in the primary water-water reactor circulation loop. In
principle, such an evaluation is a multidisciplinary task that covers not
only the irradiation of the nuclei, the formation of new isotopes and their
decay when they are unstable, but also calculations in the field of
hydraulics in order to perform an assessment of the irradiation time and the
decay time. A general and a more detailed review of the radiation sources
formation in the nuclear facilities and the pool type research reactors with
demineralized water as a heat carrier are prepared. The initial isotopic
composition of the heat carrier has been adopted according to the Vienna
Standard Mean Ocean Water recommended by the International Atomic Energy
Agency. The general mathematical model of the processes of nuclei
irradiation, the formation of new isotopes and their decay, the assessment
of the irradiation time and the decay time is described in details, enabling
the repetition of this evaluation to a particular facility. The presented
approach is applied in the reconstruction design of the nuclear research
reactor IRT-2000, Sofia, Bulgaria.
Seasonal variation of indoor and outdoor gamma dose rates of Reasi district of Jammu and Kashmir
Authors: Kaur Manpreet , Kumar Ajay , Mehra Rohit , Mishra Rosaline
Published: June 2018

In the present study, the indoor gamma dose rate has been studied seasonally
and the outdoor gamma dose rate was also measured in and around the 24
dwellings of 10 villages of Reasi district of Jammu and Kashmir, India, at
about one meter above the ground surfaces by using Dosimeter-Radiometer
MKS-03 (SARAD). The study was carried out to assess the annual equivalent
dose rate for the inhabitants of the dwellings. The survey was designed in
such a way so as to obtain a uniform and representative distribution of
measurements locations. The indoor to outdoor dose ratio was calculated as
1.8, which indicated that the indoor gamma dose rate as compared to outdoor
gamma dose rate has elevated levels of radon exposure due to confined space
and poor ventilation. The average indoor gamma dose rate for three seasons
such as winter, summer, and rainy were 0.18 ? 0.02, 0.12 ? 0.03, and 0.15 ? 0.03
?Svh-1, respectively. It was observed that the indoor gamma dose rate during
the winter season is higher than those for rainy and summer seasons. The
indoor and outdoor annual equivalent dose rate was also measured from the
health hazard point of view and it varied from 771 ? 210 to 1402 ? 280 ?Svy-1 and
105 ? 53 to 315 ? 105 ?Svy-1. These results revealed that the outdoor equivalent
dose rate levels in all of the locations were below the 1000 ?Svy-1
maximum permissible limit for the public set by International Commission on
Radiological Protection, except the few locations of indoor equivalent
dose rate.
Radium content in Bulgarian mineral waters
Authors: Kamenova-Totzeva Rositza , Totzev Alexandar , Kotova Radostina
Published: June 2018

This study presents the results of 226Ra content in 104 Bulgarian mineral
waters as well as the investigated correlations between the physicochemical
parameters, geological structure, and specific activity of 226Ra. The results
show that the 226Ra activities range from <30 mBqL-1 to 4900 mBqL-1 with a
mean value of 156 mBqL-1. The highest concentrations of 226Ra were measured
in mineral waters originating from the carbonate strata, as the dominant
geological structure. Thus it is well connected with the estimated moderate
positive correlation between Ca2+, Mg2+, and Ra2+ cations in the water. The
estimated annual dose shows large dispersion of values ranging from 6 ?Sv to
1000 ?Sv with a mean value of 32 ? 9 ?Sv. The results demonstrate the need
for further investigation of every mineral water, but greater attention
should be given to the mineral waters with low pH and high content of Ca2+
and Mg2+.
Open game fences and their socio-spatial effects: Placing red deer, placing humans, managing territories
Authors: Baltzinger Marie , Mårell Anders , Deconchat Marc , Barrier Rachel
Published: June 2018

Big game populations have been rapidly increasing in temperate and boreal ecosystems worldwide, which has prompted the need to study the socio-ecological issues related to their management. In addition, the use of game-fencing has been spreading in certain rural areas, especially in French Sologne. These two parallel trends raise the issue of the new socio-spatial arrangements developing in rural areas. We set up an in-depth case-study combining stakeholder-interviews and ecological surveys (red deer trails, pellets and bed sites) to understand how game fences may affect both animal and human mobility, and why this may raise human conflicts. The study site was a 17.52 km² fenced landscape comprising a public forest bordered on the north and south by two privately owned fenced lots. Both the interviews and the ecological data indicated that the fences were crossable for red deer. We did not find any fencing effect on the location of red deer trails, though red deer pellet groups were significantly more frequent outside fenced lots. On the other hand, we recorded more bed sites within fenced lots, in accordance with the stakeholders’ statements that fenced lots had a high sheltering value for red deer. This implies that stakeholders have contrasting opportunities to encounter red deer because the fences deter non-owners from trespassing. Although any private owner has the legal right to fence his or her land under French law, our finding calls for more attention to how the fencing is designed, since its effects may impact the surrounding landscape. For instance, fences can allow a single owner to impose game management policies in the areas surrounding his or her estate.
A Generalizable Framework for Multi-Scale Auditing of Digital Learning Provision in Higher Education
Authors: Ross Samuel Robert Peter-James , Volz Veronica Elizabeth , Lancaster Matthew K , Divan Aysha
Published: June 2018

It is increasingly important that higher education institutions can audit and evaluate the scope and efficacy of their digital learning resources across various scales. To-date there has been little effort to address this need for a validated, appropriate and simple to execute method that will facilitate such an audit; whether it be at the scale of an individual programme, department, faculty or institution. The data are of increasing value to ensure institutions maintain progress and equity in the student experience as well as for deployment and interpretation of learning analytics. This study presents a generalizable framework for auditing digital learning provision in higher education curricula. The framework is contextualized using a case study in which the audit is conducted across a single faculty in a research-intensive U.K. university. This work provides academics and higher education administrators with key principles and considerations as well as example aims and outcomes.
Small Groups in a Social Learning MOOC (slMOOC): Strategies for Fostering Learning and Knowledge Creation
Authors: Krasny Marianne , DuBois Bryce , Adameit Mechthild , Atiogbe Ronnie , Baih Lukman , Bold-erdene Tergel , Golshani Zahra , González-González Rodrigo , Kimirei Ishmael , Leung Yamme , Shian-yun Lo , Yao Yue
Published: June 2018

Social support and face-to-face learning may enhance outcomes for students who face barriers in accessing Massive Open Online Courses (MOOCs). In this study, we investigated how self-identified volunteer leaders guide and foster interactions among small groups of students who face technical and conceptual barriers in accessing MOOC content. Several months prior to the start of the MOOC (Environmental Education: Trans-disciplinary Approaches to Addressing Wicked Problems), we asked for volunteers among the registered students to lead groups for participants whose primary language was other than English and where limited Internet access, culture, or other barriers curtailed access to and understanding of course materials and pedagogy. Based on a survey and open-ended interviews (n=10), we found that group leaders were instrumental in overcoming barriers related to language, content, cultural ways of learning, access, and time. They also fostered cooperative learning strategies, which helped students acquire course content, and encouraged collaborative group projects leading to their groups adopting some features of online knowledge communities. We propose the term social learning MOOC (slMOOC) to capture a growing trend of incorporating collaborative learning strategies in xMOOCs.
Una bienvenida a la investigación científica
Authors: DE LA OSSA JAIME
Published: June 2018

Es un honor poder presentar una revista de divulgación científica planeada, discutida y creada en nuestra Facultad de Ciencias Agropecuarias de la Universidad de Sucre, más aún si se tiene en cuenta que han transcurrido 54 años desde 1955 hasta el día de hoy, para que un medio escrito de divulgación de la productividad intelectual científica vuelva a ver la luz en estas tierras.
Regresión logistica en la evaluación de la esporulación de micorrizas en pasto bothriochloa pertusa (l) a. Camus.
Authors: PEREZ C ALEXANDER , FUENTES JUSTO
Published: June 2018

El objetivo del presente trabajo fue obtener una función logística o función de probabilidad que permitiera medir las posibilidades de ocurrencia del evento esporulación de hongos formadores de micorrizas arbusculares nativos, asociados al pasto Bothriochloa pertusa (L) A. Camus, localizas en fincas ganaderas de cuatro zonas agroecológicas, municipio de Corozal, Colombia, como respuesta a la actividad de ciertos factores químicos del suelo tales como: pH, Materia Orgánica, Fósforo, Potasio. Las muestras de suelo fueron colectadas en fincas ganaderas sembradas con pasto colosuana. El aislamiento, el conteo de esporas/ 100 g de suelo y la identificación de los hongos fue realizadas en el laboratorio de microbiología de la Universidad de Sucre. El modelo o función de probabilidad creada fue utilizado para medir las posibilidades de ocurrencia de la esporulación como respuesta a la presencia de ciertos factores químicos del suelo. Para obtener esta función logística se determinó la importancia de cada uno de estos factores de riesgo y sus posibles interacciones. Fueron muestreadas 48 fincas ganaderas distribuidas en cuatro zonas agroecológicas diferentes, la cantidad esporas/ 100 de suelo, oscilo entre (900) 2600 – 4000 (7300); se aislaron 31 morfotipos nativos de hongos formadores de micorrizas arbusculares distribuidos en dos géneros Glomus y Gigospora, predominando en su mayoría especies del género Glomus. El proceso de modelación logística encontró que los factores que mejor explican el fenómeno de la esporulación de hongos formadores de micorrizas asociados a rizosfera de pasto colosuana fueron el pH y el Potasio.