bluuebunny/crossref_metadata_2025 huggingface dataset:
Is Continued Improvement After Automated Virtual Reality Exposure Therapy for Spider Phobia Explained by Subsequent in-vivo Exposure? A First Test of the Lowered Threshold Hypothesis
Authors: Lindner Philip , Dafgård Peter , Miloff Alexander , Andersson Gerhard , Reuterskiöld Lena , Hamilton William , Carlbring Per
Published: May 2021

Consumer Virtual Reality (VR) technology offers a powerful, immersive medium for scalable dissemination of mental health interventions. Decades of research has shown VR exposure therapy to be efficacious in the treatment of anxiety disorders and that the fear reduction generalizes to real-world stimuli. Many studies also report continued improvement over time, after discontinuing VR use. The lowered threshold hypothesis states that this continued improvement is moderated by lowering the threshold to conduct subsequent in-vivo exposure. The current study is the first to formally test this hypothesis, using data from a recent trial on automated VR exposure therapy for spider phobia, in which participants (n = 49) were followed for 1 year, completing assessments 1 week, 3 and 12 months post-treatment. The assessment included validated self-report of phobia symptoms, a standardized behavioral approach test featuring a real spider, and a questionnaire for self-reporting frequency of in-vivo exposures since last assessment. Number of in-vivo exposures was found to be independently associated with greater symptom decrease in longitudinal outcome models. In sequential structural equation models, immediate post-treatment symptom reduction was associated with subsequent in-vivo exposures, which in turn was associated with continued symptom reduction. However, this applied only to self-reported phobia symptoms (not behavioral avoidance) and no associations were found past 3 months. Our findings offer preliminary, partial support for the lowered threshold hypothesis, suggesting that VR exposure interventions may benefit from including explicit in-virtuo to in-vivo transitioning components.
Inter-class Concomitant Pharmacotherapy in Medicaid-Insured Youth Receiving Psychiatric Residential Treatment
Authors: Edelsohn Gail A. , Eren Kemal , Parthasarathy Meghna , Ryan Neal D. , Herschell Amy
Published: May 2021

Background: Concomitant pharmacotherapy has become increasingly common in the treatment of youth, including in psychiatric residential treatment facilities (PRTF) despite limited efficacy and safety data. Research is reported on the prevalence of any class and interclass concomitant pharmacotherapy, specific class combinations of psychotropics, and changes in number of medications from admission to discharge for Medicaid insured youth treated in PRTFs in one mid—Atlantic state.

Methods: Medicaid administrative claims data were examined for youth under age 18 years who were discharged from one of 21 PRTFs during calendar year 2019. Descriptive statistics were calculated to examine patterns of service utilization 90 days prior to admission. The rates of concomitant psychotropic use at admission were compared to the rates at discharge. Logistic regression models were used to examine covariates associated with discharging on 4 or more medications.

Results: Fifty-four % of youth were admitted on either two or three psychotropics, while 25% were admitted on four or more psychotropics. The proportion of youth admitting and discharging on 2 or 3 medications was stable. There was a 27% increase in number of youth discharging on 4 medications with a 24% decrease in those on a 5- drug regimen. Only the number of medications prescribed at admission was found to be significant (p < 0.001), with more medications at admission contributing to probability of discharging on 4 or more medications.

Conclusions: Concomitant pharmacotherapy is common in PRTFs. These findings support the practice of deprescribing and underscore the need for further research.
Preoperative Serum Metabolites and Potential Biomarkers for Perioperative Cognitive Decline in Elderly Patients
Authors: Lu Wenbin , Jiang Zhengyu , Huang Jie , Bian Jinjun , Yu Xiya
Published: May 2021

Perioperative cognitive decline is one of the perioperative neurocognitive disorders common to see in elderly patients. Although POCD increases patient mortality and hospitalization time, the exact inflammatory and related mechanisms are still unknown. Besides, the diagnosis of POCD lacks a unified and straightforward evaluation neuropsychological scale. Metabolites could reveal chemical fingerprints left behind by the cellular process, which provides a new aspect to understand the biological process behind. According to the post-operative MMSE score, 56 patients who received elective orthopedics surgery were included and divided into POCD and Non-POCD groups. Preoperative serum metabolites in both groups and post-operative serum metabolites were analyzed. We then performed an SVM model using 10 differential metabolites in preoperative samples as features to evaluate the patients' risk of POCD, which appeared to be positively associated with POCD and could be a potential biomarker. We also analyzed differential serum metabolites from preoperative and post-operative samples of POCD patients. By analyzing their overlap differential metabolites with between POCD and Non-POCD patients, we further inferred seven metabolites positively related to the POCD mechanism. Our results provide a more convenient method to aid POCD diagnosis and prevention using biomarkers and explore the possible mechanism behind.
Perioperative Exercise Intention and Influencing Factors: A Multi-Centered Cross-Sectional Study
Authors: Lv Feng , Zhang Yuxi , Min Su , Li Ping , Peng Lihua , Ren Li , Yu Jian , Wang Bin , Shen Yiwei , Tong Shanshan , Jin Juying , Luo Xi , Chen Jing , Chen Yingrui , Li Yuanyuan , Chen Jin , Zeng Xing , Luo Fuquan , Xiong Qiuju , Zou Lei , Guo Yuanyuan , Cao Jun , Chen Qibin , Wu Bin , Chen Gang , Liu Xiaoli , Xie Boli
Published: May 2021

Objectives: This study aimed to evaluate the level and factors affecting the perioperative exercise intention in China.

Design: This study was a cross-sectional survey in Southwest China.

Methods: Four hundred and ninety nine participants were randomly sampled in eight medical centers from November 23, 2020 to November 27, 2020. The survey included sociodemographic information and a 24-item modified questionnaire, which aimed to evaluate the attitude toward daily exercise, perception of perioperative exercise, social support and the perioperative exercise intention. A multivariable linear regression model was used to evaluate the effect of different items on the patients' intention for perioperative exercise.

Results: A total of 523 responses (95.09%) were collected and 499 (95.41%) were analyzed. The level of exercise intention of the patients during the perioperative period was: 14.83% planned to exercise every day in the hospital, 21.04% planned to exercise every other day, and 35.87% planned to exercise every week. Intensity of daily exercise (P = 0.016), positive attitude of daily exercise (P < 0.001), positive attitude of perioperative exercise (P < 0.001) and social support (P < 0.001) were positively associated with the intention for perioperative exercise. Female (P = 0.012), non-tertiary center (P = 0.011), and preoperative anxiety (P = 0.023) was negatively associated with it.

Conclusions: The intention for perioperative exercise was low in Southwest China. The authors aimed to relieve preoperative anxiety, promote the education of perioperative exercise, design perioperative exercise programs, and provide more social support from medical staff and family for inpatients undergoing elective surgery.
Changes in Oral Health Policies and Guidelines During the COVID-19 Pandemic
Authors: Jiang Chloe Meng , Duangthip Duangporn , Auychai Prim , Chiba Mirei , Folayan Morenike Oluwatoyin , Hamama Hamdi Hosni Hamdan , Kamnoedboon Porawit , Lyons Karl , Matangkasombut Oranart , Mathu-Muju Kavita R. , Mathur Vijay Prakash , Mei May Lei , Morgan Mike , Poolthong Suchit , Rahul Morankar , Srinivasan Murali , Takahashi Tetsu , Yaklai Sanicha , Zhang Shinan , Zou Xin Chun , Chu Chun Hung , Lo Edward Chin Man
Published: May 2021

The aim of this study was to describe the changes in oral health policies and guidelines in response to the Coronavirus disease 2019 (COVID-19) pandemic in different countries and regions around the world. Information on oral health policies and guidelines from 9 countries (Canada, China including Hong Kong, Egypt, India, Japan, New Zealand, Nigeria, Switzerland, and Thailand) were summarized, and sources of the information were mostly the national or regional health authorities and/or dental council/associations. The changes made to the oral health guidelines depended on the severity of the COVID-19 pandemic. This included suspension of non-emergency dental care services at the peak of the COVID-19 outbreak, and easing the restrictions on non-essential and elective dental care when the pandemic became under control. The COVID-19 risk mitigation strategies include strict adherence to infection control practices (use of hand sanitizers, facemask and maintaining social distancing), reducing the amount of aerosol production in the dental setting, and managing the quality of air in the dental treatment rooms by reducing the use of air conditioners and improving air exchange. The COVID-19 pandemic has shown a major impact on dental practice. Dental professionals are trying to adapt to the new norms, while the medium to long-term impact of COVID-19 on dentistry needs further investigation.
Powering Life in the Water: Phytoplankton in the San Francisco Estuary
Authors: Parker Alexander E. , Lehman Peggy W.
Published: May 2021

Phytoplankton are probably the most important aquatic organisms that you have NEVER seen! Phytoplankton are nearly invisible and use sunlight, carbon dioxide, and nutrients in water to produce sugars that power the estuary food web. The amount of phytoplankton growth is important because phytoplankton are the food for aquatic animals like zooplankton and fish. Scientists working in the San Francisco Estuary are concerned because phytoplankton growth is low, and some animals are starved for food. Measuring phytoplankton growth is hard because growth is low and the conditions in the water that control growth change quickly. As a result, scientists created a mathematical equation, called a model, that brings together the number of phytoplankton available to grow, the amount of sunlight, and the muddiness of the water to estimate phytoplankton growth each day. This way, scientists can determine where and when food is available to power life in the San Francisco Estuary.
Essential Oils and Their Application in Food Safety
Authors: Maurya Akash , Prasad Jitendra , Das Somenath , Dwivedy Abhishek Kumar
Published: May 2021

Food industries are facing a great challenge due to contamination of food products with different microbes such as bacteria, fungi, viruses, parasites, etc. These microbes deteriorate food items by producing different toxins during pre- and postharvest processing. Mycotoxins are one of the most potent and well-studied toxic food contaminants of fungal origin, causing a severe health hazard to humans. The application of synthetic chemicals as food preservatives poses a real scourge in the present scenario due to their bio-incompatibility, non-biodegradability, and environmental non-sustainability. Therefore, plant-based antimicrobials, including essential oils, have developed cumulative interest as a potential alternative to synthetic preservatives because of their ecofriendly nature and generally recognized as safe status. However, the practical utilization of essential oils as an efficient antimicrobial in the food industry is challenging due to their volatile nature, less solubility, and high instability. The recent application of different delivery strategies viz. nanoencapsulation, active packaging, and polymer-based coating effectively addressed these challenges and improved the bioefficacy and controlled release of essential oils. This article provides an overview of essential oils for the preservation of stored foods against bacteria, fungi, and mycotoxins, along with the specialized mechanism of action and technological advancement by using different delivery systems for their effective application in food and agricultural industries smart green preservative.
Non-inferiority Trial Investigating the Efficacy of Non-steroidal Anti-inflammatory Drugs and Antimicrobial Treatment of Mild to Moderate Clinical Mastitis in Dairy Cows With Long-lasting Udder Diseases
Authors: Krömker Volker , Schmenger Anne , Klocke Doris , Mansion-de Vries Ellen Maria , Wente Nicole , Zhang Yanchao , Leimbach Stefanie
Published: May 2021

To reduce ineffective antimicrobial usage in the treatment of non-severe clinical mastitis (CM) in cows with long-lasting udder diseases, non-antibiotic therapy with a non-steroidal anti-inflammatory drug (NSAID) was conducted and evaluated in a non-blinded, positively controlled, non-inferiority trial. Therefore, three-time systemic ketoprofen treatment at intervals of 24 h was evaluated in comparison with the reference treatment of solely antibiotic therapy in a field study on nine free-stall dairy farms located in Northern Germany. Cows with previous CM cases in current lactation and/or with long-lasting high somatic cell counts in preceding dairy herd improvement test days were randomly allocated to one of the two treatment groups in cases of mild to moderate CM. Quarter foremilk samples of the affected quarters were taken for cyto-bacteriological investigation before treatment as well as ~14 and 21 d after termination of therapy. Both treatment groups were compared regarding the bacteriological cure (BC) as the primary outcome. Clinical cure (CC) and no CM relapse within 60 d after the end of treatment (no R60) were chosen as secondary outcomes. The study resulted in the following outcomes: Streptococcus uberis was most frequently identified in microbiological culture from pre-treatment samples, followed by Staphylococcus aureus and Escherichia coli and other coliforms. No significant differences between the NSAID treatment and the reference treatment were detected regarding CC and CM recurrence (no R60). Although the sole ketoprofen therapy resulted in a numerically lower likelihood of BC, there were no significant differences to the reference treatment. Considering the selection criteria in this study, the results indicate that in mild to moderate CM cases exclusive treatment with ketoprofen may constitute an alternative to antimicrobial intramammary therapy, providing an opportunity for reduction of antibiotic usage. However, non-inferiority evaluations were inconclusive. Further investigations with a larger sample size are required to confirm the results and to make a distinct statement on non-inferiority.
Macrocirculatory Parameters and Oxygen Debt Indices in Pigs During Propofol Or Alfaxalone Anesthesia When Subjected to Experimental Stepwise Hemorrhage
Authors: Lervik Andreas , Forr Toverud Simen , Bohlin Jon , Haga Henning Andreas
Published: May 2021

Background: Pigs are anesthetized when used for emergency procedures live tissue training (LTT) of civilian and military medical personnel or for experimental purposes, but there is a paucity in the literature regarding anesthesia of pigs for this purpose.

Objective(s): The main goals of the study were to compare oxygen debt, macrocirculatory parameters, and time to cardiac arrest between pigs in hemorrhagic shock and anesthetized with propofol-ketamine-dexmedetomidine or alfaxalone-ketamine-dexmedetomidine.

Design: A prospective, non-blinded randomized study design was used. Sixteen pigs were randomized in blocks of four to be anesthetized with either propofol-ketamine-dexmedetomidine (n = 8) or alfaxalone-ketamine-dexmedetomidine (n = 8) as a continuous infusion.

Interventions: Premedication with ketamine 15 mg kg−1 and midazolam 1 mg kg−1 was given i.m. Anesthesia was maintained with propofol 8 mg kg−1 h−1 or alfaxalone 5 mg kg−1 h−1 combined with ketamine 5 mg kg−1 h−1 and dexmedetomidine 4 μg kg−1 h−1 i.v. A stepwise, volume-controlled model for hemorrhage was created by exsanguination.

Main Outcome Measures: Indices of oxygen debt (lactate, base excess, and oxygen extraction), macrocirculatory (PR, SAP, DAP, MAP, and CI, SVI, and TPR) variables, and time to death was compared between groups.

Results: Pigs in the alfaxalone group had significantly higher SAP than pigs given propofol. No difference in other macrocirculatory variables or indices of oxygen debt could be found. A blood loss of 50% of the total blood volume or more was possible in most pigs with both anesthetic regimes.

Conclusions: Pigs anesthetized with propofol or alfaxalone combined with ketamine and dexmedetomidine tolerated substantial blood loss.
Effects of Dietary Maltol on Innate Immunity, Gut Health, and Growth Performance of Broiler Chickens Challenged With Eimeria maxima
Authors: Park Inkyung , Goo Doyun , Nam Hyoyoun , Wickramasuriya Samiru S. , Lee Kichoon , Zimmerman Noah P. , Smith Alexandra H. , Rehberger Thomas G. , Lillehoj Hyun S.
Published: May 2021

Two studies were conducted to evaluate the effects of maltol as a postbiotic on innate immunity, gut health, and enteric infection. In the first study, an in vitro culture system was used to evaluate the effects of maltol on the innate immune response of chicken macrophage cells (CMC), gut integrity of chicken intestinal epithelial cells (IEC), anti-parasitic activity against Eimeria maxima, and differentiation of quail muscle cells (QMC) and primary chicken embryonic muscle cells (PMC). All cells seeded in the 24-well plates were treated with maltol at concentrations of 0.1, 1.0, and 10.0 μg. CMC and IEC were stimulated by lipopolysaccharide to induce an innate immune response, and QMC and PMC were treated with 0.5 and 2% fetal bovine serum, respectively. After 18 h of incubation, pro-inflammatory cytokines, tight junction proteins (TJPs), and muscle cell growth markers were measured. In the second study, the dietary effect of maltol was evaluated on disease parameters in broiler chickens infected with E. maxima. Eighty male 1-day-old broiler chickens were allocated into the following four treatment groups: (1) Control group without infection, (2) Basal diet with E. maxima, (3) High maltol (HI; 10.0 mg /kg feed) with E. maxima, and (4) Low maltol (LO; 1.0 mg/kg feed) with E. maxima. Body weights (BW) were measured on days 0, 7, 14, 20, and 22. All chickens except the CON group were orally infected with 104E. maxima per chicken on day 14. Jejunum samples were collected for gut lesion scoring, and the gene expression of cytokines and TJPs. Data was analyzed using PROC MIXED in SAS. In vitro, maltol not only increased TJPs in IEC and cytokines in the LPS-stimulated CMC but also showed direct cytotoxicity against sporozoites of E. maxima. In vivo, the HI group improved the BW, reduced the gut lesion scores and fecal oocyst shedding, and decreased jejunal TNFSF15 and IL-1β expression in E. maxima-infected chickens. In conclusion, these results demonstrate the beneficial effects of dietary maltol in the enhancement of growth performance, gut health, and coccidiosis resistance and the applicability of maltol as a postbiotic for the replacement of antibiotic growth promoters in commercial poultry production.
Thermochemistry of Combustion in Polyvinyl Alcohol + Hydroxylammonium Nitrate
Authors: Baird James K. , Frederick Robert A.
Published: May 2021

A mixture of polyvinyl alcohol (PVA) and hydroxylammoniun nitrate (HAN) forms a gummy solid known as a plastisol, which is ionically conducting. When an electrostatic potential of 200 V DC is applied across the plastisol, it ignites. Combustion ceases upon removal of the applied voltage. The products of PVA + HAN combustion are known to include the molecular gases carbon monoxide, carbon dioxide, water, nitrogen, and hydrogen. When the electric field within the plastisol is spatially uniform, combustion occurs preferentially at the anode. The fact that HAN is an ionic conductor suggests that the mechanism of combustion is electrolytic in origin. Consistent with the preference for combustion at the anode and the known gaseous products, we consider two reaction mechanisms. One involves atomic oxygen as the oxidizing agent at the anode and hydroxyl radical as the oxidizing agent at the cathode. The other involves ozone as the oxidizing agent at the anode and hydrogen peroxide as the oxidizing agent at the cathode. Each mechanism is applied to a scenario where the products are rich in the carbon oxides and to a second scenario where the products are poor in the carbon oxides. In the rich case, the heat of the overall reaction is −808.33 kJ per mole of HAN consumed and the electrical energy is converted to thermal energy with an efficiency of 4.2%. In the poor case, the corresponding figures are −567 kJ per mole of HAN and efficiency is 2.9%. The combustion reactions at the electrodes are uniformly exothermic with the exception of the reaction involving hydrogen peroxide at the cathode. When the products are poor in the carbon oxides, this reaction is actually endothermic.
Aquaculture Journal: A New Open Access Journal
Authors: Oliva-Teles Aires
Published: May 2021

Fishery production, considering both capture and aquaculture, is a major animal protein source for humans [...]
Treating the Metabolic Syndrome by Fecal Transplantation—Current Status
Authors: Malnick Stephen D. H. , Fisher David , Somin Marina , Neuman Manuela G.
Published: May 2021

The intestinal microbiome (IM) is important for normal gastrointestinal (GI) and other organ systems’ functioning. An alteration in the normal IM, dysbiosis, and changes in intestinal motility result in microorganisms’ overgrowth and an alteration in intestinal permeability. The gut–brain axis is also of importance in the irritable bowel syndrome (IBS) and associated bowel overgrowth. Secondary to the epidemic of obesity, the metabolic syndrome has become a major health problem. Disturbances in the fecal microbiome are associated with the metabolic syndrome. Metabolic-associated fatty liver disease (MAFLD) is now the current terminology for non-alcoholic fatty liver disease. IM alteration by fecal transplantation is an approved treatment method for recurrent Clostridioides difficile infection. Initially performed by either duodenal infusion or colonoscopy, it is now easily performed by the administration of capsules containing stools. We discuss the intestinal microbiome—its composition, as well as the qualitative changes of microbiome composition leading to inflammation. In addition, we discuss the evidence of the effect of fecal transplantation on the metabolic syndrome and MAFLD, as well as its clinical indications.
Investigation of a Base-Isolator System’s Effects on the Seismic Behavior of a Historical Structure
Authors: Usta Pınar
Published: May 2021

The earthquake performance of structures with seismic isolation is much better than that of fixed-base structures, and the application of seismic insulation ensures both structural integrity and the protection of the items present in the structures. The base-isolation system is used to extend the fundamental period of vibration of the structure and to obtain higher value from base-isolated structures relative to the fixed-base structure. Historical masonry mosques could be strengthened using a base-isolation technique. In this study, a historical masonry mosque was organized and modelled using SAP2000 software. Nonlinear Time History analyses were carried out for the historical masonry structure, firstly for the fixed-base mosque and secondly for the base-isolated mosque with lead rubber bearing (LRB). The use of a base-isolator system caused an increase in the historical mosque’s period, reducing the displacements, acceleration, and force applied on the mosque and the resulting structural deformation; the results of the analysis indicate a significant improvement in the seismic behavior. The modelling results show that such historical masonry buildings (especially those with high and delicate minarets) can be vulnerable to major earthquakes, and it may be useful to examine strengthening strategies for these buildings.
KPNB1 Inhibitor Importazole Reduces Ionizing Radiation-Increased Cell Surface PD-L1 Expression by Modulating Expression and Nuclear Import of IRF1
Authors: Yoshino Hironori , Sato Yoshiaki , Nakano Manabu
Published: May 2021

Programmed death-ligand 1 (PD-L1) is an immune checkpoint molecule that negatively regulates anti-tumor immunity. Recent reports indicate that anti-cancer treatments, such as radiation therapy, increase PD-L1 expression on the surface of tumor cells. We previously reported that the nuclear transport receptor karyopherin-β1 (KPNB1) is involved in radiation-increased PD-L1 expression on head-and-neck squamous cell carcinoma cells. However, the mechanisms underlying KPNB1-mediated, radiation-increased PD-L1 expression remain unknown. Thus, the mechanisms of radiation-increased, KPNB1-mediated PD-L1 expression were investigated by focusing on the transcription factor interferon regulatory factor 1 (IRF1), which is reported to regulate PD-L1 expression. Western blot analysis showed that radiation increased IRF1 expression. In addition, flow cytometry showed that IRF1 knockdown decreased cell surface PD-L1 expression of irradiated cells but had a limited effect on non-irradiated cells. These findings suggest that the upregulation of IRF1 after irradiation is required for radiation-increased PD-L1 expression. Notably, immunofluorescence and western blot analyses revealed that KPNB1 inhibitor importazole not only diffused nuclear localization of IRF1 but also decreased IRF1 upregulation by irradiation, which attenuated radiation-increased PD-L1 expression. Taken together, these findings suggest that KPNB1 mediates radiation-increased cell surface PD-L1 expression through both upregulation and nuclear import of IRF1.
Anchor Plates Bonded on Reinforced Concrete: A Preliminary Experimental Investigation
Authors: Consiglio Andrea Nino , Muciaccia Giovanni
Published: May 2021

During the last decades, different technologies to anchor steel elements in concrete were proposed. The present work presents the results of a preliminary investigation of a new connection characterized by single steel plates that are directly bonded on concrete surfaces. The anchor response was experimentally investigated under both tension and shear actions. Specific conditions influencing the behavior of the bonded assembly were discussed, with particular reference to the presence of cracks and crack cycling in concrete.
Synovial Sarcoma: A Clinical Review
Authors: Gazendam Aaron M. , Popovic Snezana , Munir Sohaib , Parasu Naveen , Wilson David , Ghert Michelle
Published: May 2021

Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5–10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t(X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes. Similar to other STS, diagnosis can be obtained from a combination of history, physical examination, magnetic resonance imaging, biopsy and subsequent pathology, immunohistochemistry and molecular analysis. Increasing size, age and tumor grade have been demonstrated to be negative predictive factors for both local disease recurrence and metastasis. Wide surgical excision remains the standard of care for definitive treatment with adjuvant radiation utilized for larger and deeper lesions. There remains controversy surrounding the role of chemotherapy in the treatment of SS and there appears to be survival benefit in certain populations. As the understanding of the molecular and immunologic characteristics of SS evolve, several potential systematic therapies have been proposed.
Cultivation Method Effect on Schizochytrium sp. Biomass Growth and Docosahexaenoic Acid (DHA) Production with the Use of Waste Glycerol as a Source of Organic Carbon
Authors: Kujawska Natalia , Talbierz Szymon , Dębowski Marcin , Kazimierowicz Joanna , Zieliński Marcin
Published: May 2021

Inexpensive carbon sources offering an alternative to glucose are searched for to reduce costs of docosahexaenoic acid production by microalgae. The use of waste glycerol seems substantiated and prospective in this case. The objective of this study was to determine the production yield of heterotrophic microalgae Schizochytrium sp. biomass and the efficiency of docosahexaenoic acid production in various types of cultures with waste glycerol. Cultivation conditions were optimized using the Plackett–Burman method and Response Surface Methodology. The highest technological performance was obtained in the fed-batch culture, where the concentration of Schizochytrium sp. biomass reached 103.44 ± 1.50 g/dm3, the lipid concentration in Schizochytrium sp. biomass was at 48.85 ± 0.81 g/dm3, and the docosahexaenoic acid concentration at 21.98 ± 0.36 g/dm3. The highest docosahexaenoic acid content, accounting for 61.76 ± 3.77% of total fatty acids, was determined in lipid bodies of the Schizochytrium sp. biomass produced in the batch culture, whereas the lowest one, accounting for 44.99 ± 2.12% of total fatty acids, in those of the biomass grown in the fed-batch culture.
The Study of the Faba Bean Waste and Potato Peels Recycling for Pellet Production and Usage for Energy Conversion
Authors: Minajeva Aleksandra , Jasinskas Algirdas , Domeika Rolandas , Vaiciukevičius Edvardas , Lemanas Egidijus , Bielski Stanisław
Published: May 2021

The article presents the results of a study on the preparation and use of faba bean waste and potato peel pellets for energy purposes. Physical and mechanical characteristics (moisture, density, ash content) of faba bean waste and potato peel pellets were investigated. The largest fraction of flour was formed on a sieve with 1 mm holes: faba bean waste—28.2 ± 2.02 g, potato peels—29.09 ± 0.73 g. For this experiment, samples were taken by mixing faba bean waste (four variants) and potato peel in the ratio of 1:1; 1:2; 1:3; 1:4 by volume (12 samples). It was found in this study that the density of pellets (DM) ranged from 1226.22 ± 13.88 kgm−3 to 1349.79 ± 6.79 kgm−3. The pellet moisture ranged from 6.70 ± 0.04% to 3.64 ± 0.13%. The lower calorific value of dry fuel pellets ranged from 15.27 ± 0.43 MJkg−1 to 16.02 ± 0.50 MJkg−1. The ash content of the pellets ranged from 8.05 ± 0.57% to 14.21 ± 0.05%. The ST temperature of the experimentally measured mixture of faba bean waste and potato peel pellets ranged from 924 to 969 °C; the DT temperature ranged from 944 to 983 °C; the HT temperature ranged from 1073 to 1202 °C, and a change in FT temperature from 1174 to 1234 °C was observed. The temperatures were sufficiently high to melt the ash. Specific emissions of CO2, CO, NOx and CxHy did not exceed the maximum levels allowed. In summary, from the results of the study of the physical properties, combustion, and emissions of waste beans and potato peel pellets (all samples), it is evident that they are used for biofuels. The combustion process of this type of pellet is characterized by efficient combustion and minimal emissions to the atmosphere.
Sensitivity Study on the Correlation Level of Seismic Failures in Seismic Probabilistic Safety Assessments
Authors: Choi Geon Gyu , Jung Woo Sik , Park Seong Kyu
Published: May 2021

It is popular that correlated seismic failures spread over the fault tree of a seismic probabilistic safety assessment (PSA) for a nuclear power plant (NPP). To avoid the calculational difficulty of core damage frequency (CDF), the fault tree has been simplified by replacing correlated seismic failures with one typical seismic failure by assuming a full correlation among the correlated seismic failures. Then, the approximate seismic CDF of a seismic single-unit PSA (SUPSA) has been calculated for decades with this simplified SUPSA fault tree. Furthermore, current seismic multi-unit PSAs (MUPSAs) have been performed with imperfect seismic MUPSA models that were generated by combining such imperfect seismic SUPSA fault trees. The authors of this study recently developed a method that can calculate an accurate seismic CDF by converting correlated seismic failures into seismic common cause failures (CCFs). In this study, accurate and imperfect MUPSA models were created and their seismic CDFs were compared. The results of this study show that the seismic CDFs in SUPSA and MUPSA are drastically distorted and safety margins are accordingly distorted when the full correlation assumption is employed. Thus, this study shows that very careful attention should be paid to calculating and interpreting seismic CDFs for the single-unit and multi-unit NPP regulations.
The Role of Renewable Energy Sources in Alleviating Energy Poverty in Households in Poland
Authors: Biernat-Jarka Agnieszka , Trębska Paulina , Jarka Sławomir
Published: May 2021

Energy poverty is a problem that affects all member states of the European Union to a varying degree, including Poland, where about 9% of the population is at risk of energy poverty. The article aims to show the changes in energy poverty in Poland in 2010–2018. The specific goal, however, is to evaluate government measures aimed at reducing energy poverty through investments based on renewable energy sources. To present changes in the level of energy poverty in 2010–2018, the authors proposed a new synthetic measure that unifies several different measures used by researchers and allows for a comprehensive assessment of this phenomenon. The conducted research showed that in 2010–2018 there was a slow but visible decrease in the level of energy poverty in Poland. In addition, the article indicates investments in renewable energy sources that may have a positive impact on reducing the scale of energy poverty in Poland. The programs implemented with national and EU public funds, which finance investments in renewable energy sources in Poland, are also presented.
Impact of Control System Model Parameters on the Obstacle Avoidance by an Autonomous Car-Trailer Unit: Research Results
Authors: Prochowski Leon , Ziubiński Mateusz , Szwajkowski Patryk , Gidlewski Mirosław , Pusty Tomasz , Stańczyk Tomasz Lech
Published: May 2021

The introduction of autonomous cars will help to improve road traffic safety, and the use of a cargo trailer improves the energy efficiency of transport. One of the critical (collision) road situations has been considered, where immediate counteraction is required in a space that has been only partly defined. This research work was aimed at determining the impact of the trajectory planning method and the values of some parameters of the control system on the feasibility of safe avoidance of an obstacle that has suddenly appeared. The obstacle is assumed to be a motor vehicle moving on a road intersection along a collision path in relation to the autonomous car-trailer unit (CT unit) travelling at high speed. Analysis of cooperation between several non-linear models (representing the car, trailer, tyre–road interaction, and driving controller) has been carried out. Mathematical models of the control system and the CT unit have been built. The process of selection of temporary and variable parameters, applied to the control system for the time of the critical situation under consideration, has been shown. The research work carried out has made it possible to recommend appropriate parameter values for the control system.
Can Mixed-Ownership Reform Drive the Green Transformation of SOEs?
Authors: Yuan Runsen , Li Chunling , Li Nian , Khan Muhammad Asif , Sun Xiaoran , Khaliq Nosherwan
Published: May 2021

In the construction of ecological civilization, green innovation has become an important driving force for the sustainable development of state-owned enterprises (SOEs). This paper uses panel data of state-owned listed enterprises from 2008 to 2019 to explore mixed-ownership reform’s influence on the green transformation of SOEs and its specific mechanisms. The results show that the diversity of mixed shareholders, the depth of mixed equity, and the restriction of mixed equity significantly promote the SOEs’ green innovation. Moreover, there are distinctions in the impact of the shareholding ratio of heterogeneous shareholders on green innovation. Only the increase in the shareholding ratio of foreign shareholders has a positive correlation with green innovation. The mechanism tests indicate that the mixed-ownership reform plays a governance role in the green transformation of SOEs by optimizing the reasonable allocation of environmental protection subsidies and propelling environmental social responsibility’s active performance. Our study further subdivides the significant promotion effect of mixed-ownership reform on green innovation, finding that it only exists in the SOEs in heavily polluting industries and regions with a high degree of marketization. Finally, we find that the ownership structure adjustment caused by the mixed-ownership reform has improved SOEs’ environmental management system and facilitated its sustainable development capabilities.
Analytic Hierarchy Process Analysis for Industrial Application of LNG Bunkering: A Comparison of Japan and South Korea
Authors: Lee Young-Gyu , Kim Jong-Kwan , Lee Chang-Hee
Published: May 2021

From January 2020, the International Maritime Organization has regulated ship emissions to reduce sulfur content. As an alternative to this, LNG bunkering was proposed, and infrastructure and ships were deployed. Therefore, we used analytic hierarchy process AHP techniques to determine optimal methods of LNG bunkering for shipyard safety. First, we conducted a literature survey on the concept and type of LNG bunkering, global LNG bunkering trends, and features of Japan and South Korea cases and compared them. Thereafter, an expert survey was conducted, and survey data was analyzed using AHP techniques. Finally, we derived optimal methods applicable to shipyard industry. The analytical results revealed that the derived priority of the optimal LNG bunkering method of shipyard was in the order of the STS method, TTS method, and the PTS method. The result of this study can serve as a theoretical basis to make LNG bunkering safer and more economical in shipyards to prepare for the expansion of demand of LNG-fueled ships and LNG. However, this study inevitably has limitations of ranking reversals paradox as it was conducted by experts, assuming no weights to STS, TTS, or PTS.
Comparative Study on Relative Fossil Energy Carrying Capacity in China and the United States
Authors: Zuo Zhili , Cheng Jinhua , Guo Haixiang , Li Yonglin
Published: May 2021

Based on resource carrying capacity, this study used the revised theory of relative resource carrying capacity (RRCC) and introduced an innovative concept of relative fossil energy carrying capacity (RFECC), which evaluates the degree of fossil energy sustainability based on the relationship between economy, population, and environment. This study took China and the United States as the study objects, took the whole country as the reference area, and calculated the RFECC of population, economic, and environmental resources from 2000 to 2018. Therefore, based on the comparative analysis, the following conclusions were drawn: (i) there is a big difference in the RFECC between China and the United States, which is manifested in the inverted U-shaped trend in China and the U-shaped trend in the United States; (ii) the relative fossil energy carrying states in China and the United States are different, mainly reflected in the economy and environment; (iii) the gap in RFECC between China and the United States has gradually widened; in general, China’s economic RFECC is better than that of the United States, while environmental RFECC and population RFECC in the United States is better than that of China; and (iv) coal and oil should be used as a breakthrough point for the sustainable fossil energy and sustainable development for China and the United States, respectively.
Kinetic Regularities of Methane Dry Reforming Reaction on Nickel-Containing Modified Ceria–Zirconia
Authors: Fedorova Valeria , Simonov Mikhail , Valeev Konstantin , Bespalko Yuliya , Smal Ekaterina , Eremeev Nikita , Sadovskaya Ekaterina , Krieger Tamara , Ishchenko Arcady , Sadykov Vladislav
Published: May 2021

The Ni-containing catalysts based on ceria–zirconia doped with Ti and Ti+Nb were prepared by the solvothermal method in supercritical fluids. Ni deposition was carried out by incipient wetness impregnation and the one-pot technique. All materials were investigated by a complex of physicochemical methods (XRD, BET, TEM, H2-TPR). Samples catalytic properties were studied in methane dry reforming in the plug-flow reactor. Conversions of CH4 and CO2, H2/CO ratio, and CO and H2 yields were measured, and detailed kinetics analysis was carried out. The influence of Ni loading method and support modification on the catalytic behavior in the methane dry reforming process was studied. The preparation method of catalysts affects the textural characteristics. For one-pot samples, pore volume and surface area are lower than for impregnated samples. For catalysts on modified supports, strong metal–support interaction was shown to increase catalytic activity. A reduction pretreatment of samples was shown to have significant influence on their catalytic properties. The kinetic parameters such as reaction rate constant at 700 °C, effective activation energy, and TOF were estimated and analyzed.
Feasibility and Adoption of a Focused Digital Wellness Program in Older Adults
Authors: Tam Eric , Boas Pedro Kondak Villas , Ruaro Fernando , Flesch Juliane , Wu Jennifer , Thomas Amelia , Li James , Lopes Felipe
Published: May 2021

Digital health programs offer numerous psychological and physical health benefits. To date, digital programs have been aimed broadly at younger participants, yet older individuals may also benefit. Our study sought to demonstrate user feasibility and satisfaction in a digital wellness program for older adults. We conducted a retrospective analysis of 140 participants in a digital health wellness application that integrated guided exercises, nutrition planning and health education. Primary outcomes were active participant retention, engagement in the mobile program and user satisfaction as operationalized by NPS scores. Among 140 participants, median age was 59.82 (50–80), 61% female, in a sample taken in the United States. Engagement was high and sustained, with more than 65% participants engaged, operationalized as at least completing one task activity a month over 17 weeks. Participants were also satisfied with the program, reporting NPS scores of 43 on day 30 of the program. Secondary health outcomes included 3.44 pound weight change during the first month. User feasibility and satisfaction was demonstrated in a sample of older participants for this novel digital health wellness program. Future work focused on older adult users may result in improvements in patient health outcomes and improved preventive medicine strategies.
Exploring Liu Kang’s Paris Practice (1929–1932): Insight into Painting Materials and Technique
Authors: Lizun Damian , Kurkiewicz Teresa , Szczupak Bogusław
Published: May 2021

This paper presents the results of an extensive study of 14 paintings by the pioneering Singapore artist Liu Kang (1911–2004). The paintings are from the National Gallery Singapore and Liu family collections. The aim of the study is to elucidate the painting technique and materials from the artist’s early oeuvre, Paris, spanning the period from 1929 to 1932. The artworks were studied with a wide array of non- and micro-invasive analytical techniques, supplemented with the historical information derived from the Liu family archives and contemporary colourmen catalogues. The results showed that the artist was able to create compositions with a limited colour palette and had a preferential use of commercially available ultramarine, viridian, chrome yellow, iron oxides, organic reds, lead white, and bone black bound in oil that was highlighted. This study identified other minor pigments that appeared as hue modifications or were used sporadically, such as cobalt blue, Prussian blue, emerald green, cadmium yellow, cobalt yellow, and zinc white. With regard to the painting technique, the artist explored different styles and demonstrated a continuous development of his brushwork and was undoubtedly influenced by Modernists’ artworks. This comprehensive technical study of Liu Kang’s paintings from the Paris phase may assist art historians and conservators in the evaluation of the artist’s early career and aid conservation diagnostics and treatment of his artworks. Furthermore, the identified painting materials can be compared with those used by other artists active in Paris during the same period.
Transcriptome and Metabolomic Analyses Reveal Regulatory Networks Controlling Maize Stomatal Development in Response to Blue Light
Authors: Liu Tiedong , Zhang Xiwen
Published: May 2021

(1) Background: Blue light is important for the formation of maize stomata, but the signal network remains unclear. (2) Methods: We replaced red light with blue light in an experiment and provided a complementary regulatory network for the stomatal development of maize by using transcriptome and metabolomics analysis. (3) Results: Exposure to blue light led to 1296 differentially expressed genes and 419 differential metabolites. Transcriptome comparisons and correlation signaling network analysis detected 55 genes, and identified 6 genes that work in the regulation of the HY5 module and MAPK cascade, that interact with PTI1, COI1, MPK2, and MPK3, in response to the substitution of blue light in environmental adaptation and signaling transduction pathways. Metabolomics analysis showed that two genes involved in carotenoid biosynthesis and starch and sucrose metabolism participate in stomatal development. Their signaling sites located on the PHI1 and MPK2 sites of the MAPK cascade respond to blue light signaling. (4) Conclusions: Blue light remarkably changed the transcriptional signal transduction and metabolism of metabolites, and eight obtained genes worked in the HY5 module and MAPK cascade.
Influence of Tool Length and Profile Errors on the Inaccuracy of Cubic-Machining Test Results
Authors: Li Zongze , Ogata Hiroki , Sato Ryuta , Shirase Keiichi , Sakamoto Shigehiko
Published: May 2021

A cubic-machining test has been proposed to evaluate the geometric errors of rotary axes in five-axis machine tools using a 3 × 3 zone area in the same plane with different tool postures. However, as only the height deviation among the machining zones is detected by evaluating the test results, the machining test results are expected to be affected by some error parameters of tool sides, such as tool length and profile errors, and there is no research investigation on how the tool side error influences the cubic-machining test accuracy. In this study, machining inaccuracies caused by tool length and tool profile errors were investigated. The machining error caused by tool length error was formulated, and an intentional tool length error was introduced in the simulations and actual machining tests. As a result, the formulated and simulated influence of tool length error agreed with the actual machining results. Moreover, it was confirmed that the difference between the simulation result and the actual machining result can be explained by the influence of the tool profile error. This indicates that the accuracy of the cubic-machining test is directly affected by tool side errors.
Reversible Barrier Switching of ZnO/RuO2 Schottky Diodes
Authors: Wendel Philipp , Dietz Dominik , Deuermeier Jonas , Klein Andreas
Published: May 2021

The current-voltage characteristics of ZnO/RuO2 Schottky diodes prepared by magnetron sputtering are shown to exhibit a reversible hysteresis behavior, which corresponds to a variation of the Schottky barrier height between 0.9 and 1.3 eV upon voltage cycling. The changes in the barrier height are attributed to trapping and de-trapping of electrons in oxygen vacancies.