bluuebunny/crossref_metadata_2025 huggingface dataset:
Alpha Parameter Modeling of Nakayasu Synthetic Unit Hydrograph Based on the Watershed Shape Factor
Authors: Hidayat Acep , Limantara Lily Montarcih , Soetopo Widandi , Sisinggih Dian
Published: May 2022

The limitation of hydrograph data availability becomes an obstacle for the design of water resources. The obstacle makes the Synthetic Unit Hydrograph give the big enough benefit for the design of water resources. Ideally, every watershed has its unit hydrograph. The Nakayasu Synthetic Unit Hydrograph is one of the synthetic unit hydrographs frequently used in the analysis of design flood discharge in Indonesia. However, the Nakayasu Synthetic Unit Hydrograph concept has been widely used and evaluated in some areas in Indonesia, and there is bias in determining the watershed characteristic coefficient. This research intends to investigate the characteristic of the observed hydrograph in every watershed and the whole watershed in the South Sulawesi Province-Indonesia. The research aims to build the alpha formula using alpha modeling with the affected parameters of watershed area, river length, river bed slope, shape factor, and the time concentration. Based on the ArcGIS version 10.7, most of the watershed’s shapes are elongated. The methodology consists of analyzing observed unit hydrograph by using the Collins method and Nakayasu Synthetic Unit Hydrograph. Then the model is built by using the statistical analysis of SPSS version 23 software for obtaining the affected level of each parameter that is determined. However, the modeling analysis uses the non-linear regression after there is carried out the descriptive test. The alpha formula for the elongate watershed in the Jeneberang River is proposed.
Topological Process of Splitting DNA-Links
Authors: Mohamad Abdul Adheem , Yashiro Tsukasa
Published: May 2022

A DNA replicon is modeled by a special type of 2-component link, called a DNA-link, in which two circles form a double helix around a trivial center core curve. The DNA replication process is semi-conservative, which is interpreted as a splitting process of the DNA-link. To split this non-trivial link, the linking number must become zero, and thus an unknotting operation is necessary. Some families of enzymes act as the unknotting operation. The present paper considers two topological problems; one is to know how the linking number is reduced and the other, how the enzymes are allocated at appropriate places. For the first problem, we suggest a reduction system of the linking number of a DNA-link. From this system, the number of repetitions of the procedure is obtained and this could be reduced when the DNA is previously relaxed by type I topoisomerases. For the second problem, we propose a possible conformation of the DNA-link in which the unknotting operation does not change the knot type of the core curve but decreases the writhe. This conformation could allocate type II topoisomerases to appropriate places. These models suggest that the combination of type I and type II topoisomerases efficiently reduces the linking number and it is possible to allocate enzymes by the conformation of DNA strands.
Бүс нутгийн бүсшил нь даяаршлын нэг хэсэг үү эсвэл түүний альтернатив уу?
Authors: Б Билэгжаргал
Published: May 2022

Бүс нутгийн бүсшил болон даяаршлын талаар судлаачид ямар байр суурьтай байдаг мөн эдгээр хоёр үйл явцын нийтлэг болон ялгаатай шинж чанаруудыг авч үзлээ.

 

Is Regionalization A Part of Globalization or an Alternative to It?

Abstract: This article deals with the regionalization and the globalization, researchers points of view concerning these two terms and tries to find out common and different features of these two processes.
21st century permafrost distribution under the scenario of RCP2.6 and RCP8.5 in Mongolia
Authors: Adiya Saruulzaya , Erdenebat Enkhbat
Published: May 2022

Permafrost in Mongolia is at the southern edge of the Siberian permafrost, which is most vulnerable to climate change. In this study, we used ERA5-Land data to determine the distribution of permafrost in Mongolia, and used MIROC5 data for future projection of the soil temperature. The future change of soil temperature obtained during 2020–2100 under Representative Concentration Pathways (RCP) scenarios was RCP 2.6 and RCP 8.5 respectively. This is a first attempt to identify the distribution of permafrost using ERA5-Land data in Mongolia. We examined the projection of permafrost distribution using RCP 2.6 and RCP 8.5 scenarios in Mongolia. The rapid increase of near-surface temperature was obtained in RCP8.5 scenario during 2020-2100. Soil temperature also has a high increasing trend similar to the near-surface temperature in the RCP 8.5 scenario. Future projection suggests that permafrost will completely thaw in Mongolia when area-averaged soil temperature in Mongolia exceeds 1.8°C in comparison with the current climate.
STUDY OF CREATION AND DEVELOPMENT OF CUSTOMER BASED BRAND EQUITY AND ITS INFLUENCING DETERMINANTS IN BANKING SECTOR
Authors: Jethava Vivek , Kumar A
Published: May 2022

Banks play very critical function in move of cash in a country. With multiplied opposition in banking quarter, advertising and marketing of a financial institution turns into critical and advertising and marketing techniques an important for each financial institution. The study was carried out in Ahmedabad, India to pick out the Customer Based Brand Equity of one of the important non-public quarter banks. Customer Based Brand Equity became studied with the aid of using making use of Keller’s Brand Resonance Model. It became observed with inside which examine that Brand emotions are the maximum critical issue of Customer Based Brand Equity in Vadodara and Brand salience the least critical one. Also, all 4 additives i.e. Brand salience, Brand performance, Brand decisions and Brand emotions have been undoubtedly correlated to every different and additionally Brand resonance. Regression version became implemented to estimate Brand resonance and the effect of four components on it.
LAS CONSECUENCIAS, RETOS Y OPORTUNIDADES CAUSADAS POR EL COVID-19 EN LA EDUCACIÓN LATINOAMÉRICA: LAS PERSPECTIVAS DE COLOMBIA Y PANAMÁ.
Authors: Mauris De la ossa. Leonardo Alberto
Published: May 2022

El confinamiento de 137 millones de estudiantes de todos los países de la región desnudó profundas crisis por años ignoradas: desigualdades sociales y económicas, falta de cobertura de internet, desproporción en la distribución de los medios tecnológicos. En este marco, una de las consecuencias ha sido que más de 3,1 millones de alumnos no hayan vuelto a las escuelas y un tercio no recibiera formación adecuada. En tal sentido, esta investigación ha tenido como principal objetivo determinar las consecuencias, retos y oportunidades causadas por el COVID-19 en la educación primaria y secundaria en Latinoamérica, en especial, Colombia y Panamá. Su interés se centró en estudiar los principales factores que contribuyeron a reinventar los sistemas educativos y las oportunidades que generó la crisis. Para ello, se siguió la metodología de la investigación cualitativa con énfasis en el análisis documentada. En cuanto al proceso para la recolección de datos estuvo sustentada en la lectura de documentos oficiales de entidades o comunidades científicas ampliamente reconocidas por su rigurosidad. Los criterios bajo los cuales se sistematizó la información fueron: consecuencias, retos y oportunidades que desveló la pandemia en el sector educativo colombo-panameño. Entre los resultados se enumeran, primero: los países latinoamericanos no se encontraban preparados para la crisis; Segundo: Aunque existieron decididos esfuerzos de los gobiernos y la sociedad civil, muchos de ellos fueron insuficientes para paliar la situación; 3: El COVID-19 empujó a los sistemas educativos a explorar técnicas de enseñanza-aprendizaje que deben seguir transitándose y 4: los procesos de formación, después de la pandemia, no serán iguales. En conclusión, si bien una pandemia en ningún escenario es deseable, en el caso de la educación, a pesar de las profundas crisis que generó, propició un espacio que invita a las naciones latinoamericanas, en especial Colombia y Panamá, a que lo exploren.
The Role of Social Shopping in the Growth of Social Commerce
Authors: Duarte Santos José
Published: May 2022

More and more companies seek to contact customers through various channels, provide new forms of interaction, allowing the customer to have integrated experiences, have access to products and services without great effort, and preferably be able to acquire them without having to change platforms or open a new window in the browser.
RAÍZES DA DEMOCRACIA EDUCATIVA E RACIAL
Authors: Medeiros Elisandra Rodrigues de
Published: May 2022

O processo de luta para a democratização educativa para estudantes negros no Brasil não se deu com o advento das cotas raciais. Esse movimento iniciou muito antes e foi marcado por ferrenhas batalhas políticas e institucionais, sendo parte da história da educação brasileira. Dada a relevância desse tema para a comunidade científica, este artigo buscou discorrer sobre a história do Movimento Negro no Brasil, destacando sua importância para a educação.
ESFORÇO HISTÓRICO DAS PARCERIAS PÚBLICO-PRIVADAS
Authors: Rosa Ivaldo Ramos
Published: May 2022

O papel que os acordos de Parcerias Público-Privadas (PPP) têm desempenhado nas últimas décadas não apenas demonstrou que essas parcerias respondem efetivamente às necessidades exigentes de infraestrutura e serviços públicos: também enfatizou a existência de um papel complementar e desimpedido do setor privado e público, devido à sua dinâmica e adaptabilidade. Diante dessa constatação, este estudo buscou caracterizar as Parcerias Público-Privadas (PPP) a partir do detalhamento do seu esforço histórico de constituição. Espera-se que ambas as iniciativas resultem em um processo de padronização entre os níveis estadual e municipal de governo, o que facilitará maior compreensão e aceitação de esquemas de PPP entre os diversos atores que poderiam eventualmente apoiar essas transações, como investidores institucionais e órgãos da sociedade civil.
CONSIDERAÇÕES SOBRE ADMINISTRAÇÃO PÚBLICA
Authors: Rosa Ivaldo Ramos
Published: May 2022

A inclusão da população na transformação do Estado implica a inserção da participação cidadã em seu redesenho institucional, bem como na formulação e gestão de políticas públicas. A transversalidade da participação, portanto, não só garante o controle e a fiscalização dos agentes governamentais, mas também dá legitimidade a um processo que exige amplo consenso, credibilidade e aceitação. Diante disso, é imperioso desvelar as concepções basilares da administração pública a fim de se defender a democracia e a igualdade de direitos.
DOIS LADOS DAS PARCERIAS PÚBLICO-PRIVADAS SOB O MODELO PROCESSUAL DE ANÁLISE
Authors: Rosa Ivaldo Ramos
Published: May 2022

Neste artigo, abordaremos o tema parcerias público-privadas (PPPs). Inicialmente, apresentaremos as nuances em torno de seu conceito. Em seguida, ele falará sobre a classificação que estes têm e o estabelecido pelo regulamento. Em seguida, detalhará as fases das PPPs, focando especificamente em algumas delas.  Por fim, falará sobre os atores envolvidos em PPPs, com exemplo de casos nacionais, de acordo com cada uma de suas fases, dando exemplos de casos nacionais ao longo do artigo sob o modelo processual de análise.
ATENÇÃO PRIMÁRIA DA SAÚDE
Authors: Souza Rodolpho Fernandes de
Published: May 2022

A Atenção Primária à Saúde (APS) é definida como um conjunto de medidas voltadas não apenas para prevenir o aparecimento de diversas doenças, como a redução de fatores de risco, mas também para impedir sua progressão e mitigar suas consequências uma vez estabelecidas. Diante disso, o presente artigo tem a meta de detalhar conceitualmente a Atenção Primária à Saúde (APS) em prol de sua publicização e posterior difusão no âmbito da saúde pública. Dessa forma, para que os níveis de atenção funcionem corretamente, deve haver um sistema de referência e contrarreferência que permita a continência ou capacidade operacional de cada um deles.
ESPAÇO DE CONFLITO
Authors: Meloti Sandra de Fátima Petri
Published: May 2022

A escola é uma das instituições mais afetadas em cenários de conflito, porque não só seu dia é alterado, mas seu funcionamento depende em grande medida do que está passando com a sociedade e a forma como os atores em conflito respeitam os direitos dos demais. Diante desse cenário, este estudo busca caracterizar a escola como um espaço de conflito, destacando os riscos ocupacionais para os membros da comunidade escolar. Assim, é de extrema importância que os ambientes escolares comecem a construir uma reflexão sobre os efeitos que os conflitos trazem para as escolas brasileiras.
POLÍTICA DE COTAS SOCIAIS EM INSTITUIÇÕES PÚBLICAS DE ENSINO SUPERIOR
Authors: Silva Maria do Socorro Barbosa e
Published: May 2022

Entende-se por cotas, um modelo de política de ações afirmativas a fim de garantir menores desigualdades socioeconômicas e educacionais entre os membros pertencentes a uma sociedade, principalmente no que se refere ao ingresso em instituições públicas de ensino superior. As cotas sociais foram instauradas para minimizar a diferença de oportunidades entre os alunos da rede pública e da rede privada. Diante disso, este artigo buscou detalhar a política de cotas sociais sob as perspectivas global, regional e local. Destaca-se que, no Brasil, o Sistema de Cotas também foi instaurado através de ações afirmativas, as cotas em processos seletivos para ensino superior foram regulamentadas pela Lei 12.711/2012 que beneficia o acesso de estudantes da rede pública em Instituições de Ensino Superior Federais, com separação de vagas para candidatos de baixa renda, negros e índios. Portanto, fica evidente a relevância deste estudo para a comunidade acadêmico-científica.
Kant als Klassiker der Philosophie
Authors: Wilken Anne
Published: May 2022

This work analyses the interrelationship between the formation of a philosophical canon and the practice of editing, using the Akademie edition of Kant's writings as an example, and thus addresses a research desideratum. It focuses on the question of whether inner-philosophical discourses found their way into the editing process in this instance. Specifically, this study examines the philosophical controversy surrounding the first and second editions of the ‘Critique of Pure Reason’. Starting with neo-Kantianism, the analysis of the Akademie edition, whose compilation was presided over by Wilhelm Dilthey, forms the heart of the work. This project is related to the Kant edition by Ernst Cassirer as well as to other available texts by Kant within the classic book series.
Inhärente Befugnisse internationaler Schiedsgerichte
Authors: Holzer Anna Marie
Published: May 2022

International arbitral tribunals may have recourse to inherent powers to the extent that it is necessary for the realisation of core judicial functions. This may also include a power of reconsideration of partial decisions.

The legal quality and effects of partial decisions issued after bifurcation are discussed in detail and it is suggested that the principle of proportionality be used to identify particular inherent powers. One chapter is devoted to the special problems of partial decisions under the ICSID Convention and the ICSID Arbitration Rules and shows possibilities for reconsideration in accordance with these provisions.
Distributed Ledger als Instrument einer dezentralen Energiewende
Authors: Zerche Jan
Published: May 2022

The challenges of a sustainable energy supply have become a political issue of decisive importance termed as "energy transition": The expansion of renewable energy plants aims at compensating for the loss of conventional energy generating capacities, which guarantee that sufficient electrical power is available even in times of unsteady demand. Distributed registers have the potential to (r)evolutionise energy supply structures: The doctoral thesis investigates inherent challenges concerning energy and data protection law of the disruptive technology in the light of the market integration of renewable energies.
Spiritualität der Sozialen Arbeit
Authors: Groß Michael
Published: May 2022

The core message of this book is that good social work is not possible without personal spirituality. Using Hartmut Rosa's resonance theory and Meister Eckhart's doctrine of being, the author shows that we humans are connected to our counterparts and God, our other self, according to our innermost nature. Avoiding this ‘implicit’ spirituality means alienation and unhappiness. Allowing it individually means a successful life and it forming the professional centre of any social engagement. The relevance of this thesis is demonstrated by three typical challenges in everyday professional life.

Michael Groß is a theologian and has been working in social organisations for over 30 years.
Predictive Value of High-sensitivity C-reactive Protein to Albumin Ratio and Monocyte to High-density Lipoprotein Ratio in Patients with Brucellosis
Authors: Sirin Mumtaz Cem , Cicioglu Aridogan Buket , Sesli Cetin Emel , Sirin Fevziye Burcu , Nurlu Temel Esra , Unal Onur
Published: May 2022

Background: Brucellosis is an inflammatory disease that may affect any organ or system. Objectives: The aim of this retrospective cross-sectional study was to investigate the predictive value of novel and traditional inflammatory markers for the diagnosis of brucellosis. Methods: The demographic characteristics and laboratory results of 55 patients with confirmed brucellosis and 60 healthy controls were analyzed and compared. Blood culture was performed using the BacT/ALERT 3D automated system. The presence of Brucella antibodies was detected by both the Brucellacapt test and Brucella Coombs gel test. Complete blood count, erythrocyte sedimentation rate (ESR), and biochemical analyzes were also performed. Results: Compared to healthy controls, the patients with brucellosis had significantly higher high-sensitivity C-reactive protein (hsCRP), hsCRP to albumin ratio (CAR), ESR, monocyte, monocyte to high-density lipoprotein ratio (MHR), aspartate aminotransferase, creatinine levels, while had significantly lower mean platelet volume, lymphocyte to monocyte ratio, albumin, total cholesterol, and high-density lipoprotein levels. There was no significant difference between the two groups in terms of leukocyte count, neutrophil, lymphocyte, hemoglobin, red blood cell distribution width, platelet, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, glucose, alanine aminotransferase, blood urea nitrogen, triglyceride, low-density lipoprotein levels. Positive correlations were observed between CAR, hsCRP, ESR, and MHR levels. Conclusions: This is the first study evaluating the predictive value of CAR and MHR in the diagnosis of brucellosis. The data revealed that CAR and MHR could be used as the markers of systemic inflammation in patients with brucellosis.
Isolation and Analysis of the Biological Characteristics of a Novel Bacteriophage vB_SauP_P992 Against Staphylococcus aureus
Authors: Agbo Elvis , Ye Zichen , Tang Zijun , Chen Yangming , Wang Ting , Fu Qiang
Published: May 2022

Background: Staphylococcus aureus is one of the most virulent pathogens inducing various diseases in humans and animals. Disturbingly, the degree and rate of drug resistance in this pathogen have sharply increased and have become a global concern. Objectives: This study analyzed the lytic activity and the biological characteristics of a mitomycin C-induced bacteriophage from S. aureus isolated and identified from hospital sewage to explore novel antibacterial therapeutic strategies for the clinical treatment of drug-resistant S. aureus, including urinary tract infections caused by MRSA strains. Methods: The new bacteriophage vB_SauP_P992, which can effectively lyse the MRSA strain, was successfully isolated and purified using the double agar plate method. In this regard, pH sensitivity, one-step growth curve, the optimal multiplicity of infection (MOI), thermo-sensitivity, phage host range, and the effects of organic reagents on phage activity were determined. Results: Electron microscopic results showed that the bacteriophage head was hexagonal with a non-contractile tail and could form a single, neatly-bordered plaque. Moreover, the optimal MOI was 0.1. The one-step growth curve showed a bacteriophage incubation period of about 20 min, a lysis period of 90 min, and a burst size of about 65.8 PFU per infected cell. The bacteriophage vB_SauP_P992 had acceptable thermal stability, pH stability, and resistance to physical and chemical factors, indicating a bacteriophage with no capsule. Conclusions: With an intense lytic activity and acceptable stability, this novel bacteriophage lays a solid foundation to enrich the bacteriophage library and better prevent and control drug-resistant S. aureus infections.
Měkkýši PP Hrnčířské louky v Praze [Molluscs of the Hrnčířské louky Nature Monument in Prague]
Authors: Říhová Dagmar Berneška , Podroužková Štěpánka , Škodová Jana Pikulík , Kocurková Alena , Drvotová Magda , Beran Luboš , Juřičková Lucie
Published: May 2022

Hrnčířské louky NM in the southeast of Prague protects a pond system surrounded by wet meadows. Until now, only sparse data about mollusc fauna were available. In 2021, 28 snail species (26 land snails, two aquatic) were recorded during the land snail inventory. Together with older sampling that also focused on aquatic species, 47 mollusc species are known from the reserve (28 land snails, 11 aquatic snails, and eight bivalves). Due to numerous water bodies, aquatic species dominate (40%), followed by hygrophilous and wetland dwellers (21%). These are supplemented by woodland species from sparse forest stands (17.5%) and ubiquists (15%). The last three species (6.5%) belong to open-ground dwellers. At the forefront of management activities in the last decades were mowing and declining fishery production in the ponds. An endangered and internationally protected species, Vertigo angustior, which depends on regular mowing, was recorded here for the first time. A review of aquatic molluscs following changes in pond management is recommended.
The impact of pain and nocturnal cramps on sleep quality in Charcot Marie Tooth disease: a case-control study
Authors: Souza Cynthia Coelho , Vallim Julia Ribeiro da Silva , Neves Eduardo Luis de Aquino , Nunes Paula Santos , Costa Iandra Maria Pinheiro de França , Barreto Lidiane Carine Lima Santos , Garcez Catarina Andrade , Araujo Adriano Antunes de Souza
Published: May 2022

Introduction: Charcot-Marie-Tooth disease is an inherited neuropathy that presents two main forms - type 1 and type 2 -, differentiated by the speed of the nervous conduction. Our goal was to assess sleep in Charcot-Marie-Tooth disease and its relationship with pain perception and nocturnal cramps.

Material and Methods: This was a case-control study. The case group was composed of 10 volunteers diagnosed with the type 1 and 23 with the type 2. The control group was composed of 22 individuals from the same family matched by age and gender. Volunteers underwent clinical screening to assess the presence of nocturnal cramps and filled the brief pain inventory, the Chalder fatigue scale, the Epworth sleepiness scale, and the Pittsburgh sleep quality index. Sleep was evaluated by actigraphy.

Results: Type 2 patients presented a more severe perception of pain and fatigue, more time spend awake after sleep onset, and had lower sleep efficiency. The individuals who reported nocturnal cramps also had worse perception of pain, reduced sleep latency, and increased sleep fragmentation.

Conclusion: The Charcot-Marie-Tooth type 2 was related with worse sleep quality, perception of pain, and fatigue and these parameters were negatively related.
Telemedicine in sleep-related breathing disorders and treatment with positive airway pressure devices. Learnings from SARS-CoV-2 pandemic times
Authors: Franceschini Carlos Maria , Smurra Marcela Viviana
Published: May 2022

The healthcare system currently faces new challenges, which are to be addressed by finding efficient alternatives. Such factors as the growth of world population, the increase in longevity, and the fact that some diseases which used to be deadly diseases have turned into chronic pathologies, cause the number of people in need for continuous medical care to rise. This results in a healthcare system crisis, which searches for solutions as telemedicine to address the needs of patients and control excessive medical spending. Telemedicine means remote medical assistance delivered by means of technological resources, which streamline the provision of medical care, thus increasing patient’s access to healthcare and saving time and costs. As regards respiratory diseases, telemedicine is a tool that may provide for proper prevention, diagnosis, therapeutic education, monitoring of observance, and therapeutic efficacy, as well as for the early detection of exacerbations. Patients suffering from sleep-related respiratory disorders in need for positive airway pressure devices may be benefited by telemedicine to enhance positive pressure adherence and follow-up to treat their pathologies, thus providing for the delivery of remote care and follow-up, reducing costs, and increasing the chances of receiving attention from specialists in patients who live a long distance from such medical facilities. However, it is a challenging task to find a balance in the doctor-patient virtual relationship.
A mathematical model for thinning rate prediction of sheet double hydro-forming
Authors: Dinh Van , Vu Duc
Published: May 2022

Double sheet blank hydro-forming (DSBH) is a technology for forming hollow parts with complex shapes. The pair of workpieces is deformed and shaped by the high-pressure liquid inside. The material is thinned after hydraulic forming, which significantly affects the quality of the product, especially the fields with high requirements, such as the automotive and aerospace industry. The goal of optimizing input process parameters to ensure that the level of thinning into a product is within the allowable limit is posed by this study. This study considered blank holder force, forming fluid pressure, and relative thickness as candidate factors for optimization using Response Surface Method (RSM). The spherical parts were formed by the DSBH method of welding blank pairs of DC04 carbon steel material based on theoretical analysis, experiment solution, and experiment to verify the results. Experiments were performed with different combinations of parameters using the Box-Behnken design. This paper presented a mathematical model that helps determine material thinning rate according to these three process parameters in the hydro-forming of spherical parts from welded sheet metal pairs. The research results can be applied to control the input parameters in the DSBH to achieve the wall thickness of the spherical part as desired by the manufacturer.
Revista Ateliê
Authors:   Universidade do Estado de Santa Catarina, Siebert Manuela
Published: May 2022

O ateliê̂ é o foco desta revista que pretende explorar esse espaço como lugar do fazer prático e teórico, e da experiência. Um lugar de ensino e aprendizagem, de trocas e reflexões. A ideia de explorar o ateliê̂ veio da necessidade de discutir e pensar sobre esse espaço/lugar como parte de grande importância para o ensino das artes visuais tanto na graduação quanto na escola. A partir disso a revista conta com um artigo que discute as formas de ocupação e uso do ateliê̂ na graduação de artes comparando os ateliês de duas universidades, a Universidade do Estado de Santa Catarina (UDESC) e a Algoma University, em Sault Saint Marie, Canadá. A revista ainda traz o Projeto Albers, desenvolvido no Estúdio de Pintura Apotheke, que nada mais é do que uma reflexão sobre os exercícios práticos estudados em ateliê̂. Uma tradução sobre o curso preliminar da Bauhaus, o Vorkurs, o qual nos dá dimensão da importância do ateliê̂, da vivência, da prática e da experiência para o ensino de artes, e Um desafio proposto na disciplina Sobre ser artista professor, que também traz uma reflexão sobre a experiência e suas reverberações na arte.
Pathological brain lesions in girls with central precocious puberty at initial diagnosis in Southern Vietnam
Authors: Huynh Quynh Thi Vu , Ho Ban Tran , Le Nguyen Quoc Khanh , Trinh Tung Huu , Lam Luu Ho Thanh , Nguyen Ngan Thi Kim , Huang Shih-Yi
Published: May 2022

Purpose: Cranial magnetic resonance imaging (MRI) is recommended to identify intracranial lesions in girls with central precocious puberty (CPP). Yet, the use of routine MRI scans in girls with CPP is still debatable, as pathological findings in girls 6 years of age or older with CPP are limited. Therefore, we aimed to identify the prevalence of brain lessons in CPP patients stratified by age group (0–2, 2–6, and 6–8 years).Methods: This retrospective cross-sectional study recruited 257 girls diagnosed with CPP for 6 years (2010–2016). MRI was used to detect brain abnormalities. Levels of luteinizing hormone, follicle-stimulating hormone, and sex hormones in blood samples were measured.Results: Most girls had no brain lesions (82.9%, n=213), and of the minor proportion of girls with CPP that exhibited brain lesions (17.1%, n=44), 32 girls had organic CPP. Pathological findings were detected in 33.3% (2 of 6) of girls aged 0–2 years, 15.6% (5 of 32) of girls aged 2–6 years, and 3.6% (8 of 219) of girls aged 6–8 years. Hypothalamic hamartoma and tumors in the pituitary stalk were the most common pathological findings. The likelihood of brain lesions decreased with age. Girls with organic CPP were more likely to be younger (6.1±2.4 vs. 7.3±1.3 years, p<0.01) than girls with idiopathic CPP.Conclusion: Older girls appeared to have a lower prevalence of organic CPP. Clinicians should cautiously use cranial MRI for girls aged 6–8 years with CPP.
The association between idiopathic scoliosis and growth hormone treatment in short children
Authors: Park Mijin , Kim Yu Jin , Oh Kyeong Eun , Kang Eungu , Nam Hyo-Kyoung , Rhie Young-Jun , Lee Kee-Hyoung
Published: May 2022

Purpose: Idiopathic scoliosis is the most common form of scoliosis, and the risk of onset and progression has been found to correlate with growth spurts. Therefore, treatment with recombinant human growth hormone (GH) treatment in short children may initiate and/or aggravate scoliosis. The aim of this study was to investigate the relationship between idiopathic scoliosis and GH treatment in short children.Methods: The medical records of 113 subjects seen at the participating institution between January 2010 and December 2020 and who were diagnosed with GH deficiency and small for gestational age, had idiopathic short stature, and were treated with GH for at least one year were reviewed. Scoliosis was defined as a Cobb angle greater than 10 degrees as assessed using a spine x-ray. Clinical data and laboratory findings before and 12 months after GH treatment were compared.Results: There was significant increase in height, height-standard deviation score, insulin-like growth factor 1, and insulin-like growth factor binding protein 3 (p<0.001) with GH treatment. However, there were no significant differences in the average Cobb angle (6.2°±3.3° vs. 6.1°±3.5°, p=0.842) and the prevalence of scoliosis (9.7% vs. 13.3%, p=0.481) before and after one year of GH treatment. A comparative analysis of both initial Cobb angle and change in Cobb angle during GH treatment showed no relationship with other factors.Conclusion: Although GH treatment in short children increased height and growth velocity, it was not associated with development or aggravation of idiopathic scoliosis.
Pituitary apoplexy in an adolescent male with macroprolactinoma presenting as middle cerebral artery territory infarction
Authors: Agrawal Pankaj , Newbold Sally , Busaidi Ayisha Al , Kapoor Ritika R , Thomas Nick , Aylwin Simon JB , Buchanan Charles R , Arya Ved Bhushan
Published: May 2022

Pituitary apoplexy typically presents with acute headache, vomiting, visual disturbance, and confusion. Herein, we report a rare presentation of ischemic stroke due to pituitary apoplexy. A 16.5-year-old male presented with reduced Glasgow Coma Scale (GCS) score, slurred speech, right-sided hemiparesis, and bitemporal hemianopia. Magnetic resonance imaging of the brain showed a large hemorrhagic sellar/suprasellar mass and an area of cortical T2/FLAIR hyperintensity with corresponding diffusion restriction in the middle cerebral artery territory. Computed tomography (CT) intracranial angiogram showed luminal occlusion of the clinoid and ophthalmic segments of both internal carotid arteries (ICAs, left>right) due to mass pressure effect. Biochemical investigations confirmed hyperprolactinemia and multiple pituitary hormone deficiencies. Stress-dose hydrocortisone was commenced with cabergoline, followed by urgent endoscopic transsphenoidal debulking of the tumor (subsequent histology showing prolactinoma). Postoperative CT angiogram showed improved caliber of ICAs. Intensive neurorehabilitation was implemented and resulted in complete recovery of motor and cognitive deficits. At the last assessment (18.8 years), the patient remained on complete anterior pituitary hormone replacement without cabergoline. Pituitary apoplexy is a medical emergency requiring prompt recognition and treatment and should be suspected in patients presenting with sudden, severe headache; nausea; or visual disturbance and meningism. Ischemic stroke is a rare manifestation of pituitary apoplexy in the pediatric population.
Means of mitigating the risks assigned to the contractor in the EPC contract: the experience of the International Federation of Consulting Engineers and Russian civil legislation
Authors: Varavenko Victor Evgenyevich , Lyapustina Natal'ya Aleksandrovna , Kovalev Denis Vital'evich
Published: May 2022

The subject of the study is the legal conditions of mitigation (mitigation) of project risks, the bearing of which is assigned to the contractor by the terms of the EPC contract. One of the key features of the EPC contract, an agreement concluded for the implementation of an investment and construction project on a turnkey basis, is the maximum assignment to the contractor of risks associated with the failure to achieve the goals of the project. It is believed that the EPC contractor, as a professional and highly qualified representative of the construction industry, is able to manage project risks more effectively than the customer. The assignment of risk by the terms of the contract proforma to one of the parties implies the need to use organizational, economic and legal means to mitigate (mitigate) the burden of risk. This work is aimed at identifying civil legal means used by the contractor to mitigate the harmful effects of events and actions, the risk of which is assigned to him by the terms of the EPC contract and establishing the possibility of using these means in the conditions of the Russian legal system. Its achievement involves a comparative analysis of the model EPC contract - a model contract of the International Federation of Consulting Engineers for turnkey projects (FIDIC Silver Book 2017) and the norms of Russian civil legislation. В В В В В  The results of the study indicate that it is possible in principle to apply the conditions of the 2017 FIDIC Silver Book, which establish means of mitigating the contractor's burden of bearing risks, in the conditions of Russian legislation, taking into account the following exceptions: (1) a security payment cannot be used as a means of mitigating the consequences of non-fulfillment by the contractor of a natural obligation; (2) compensation for property losses cannot be applied in the event of an unlawful claim by the customer for a guarantee of performance of contractual obligations provided by the contractor. The interrelated application of several civil legal means is aimed, ultimately, their application contributes to the achievement of the project goals, which is in the sphere of interests of both parties to the contract.
Search for morphological indicators that predict implantation by principal component analysis using images of blastocyst
Authors: Mashiko Daisuke , Tokoro Mikiko , Kojima Masae , Fukunaga Noritaka , Asada Yoshimasa , Yamagata Kazuo
Published: May 2022

Background

Although the current evaluation of human blastocysts is based on the Gardner criteria, there may be other notable parameters. The purpose of our study was to clarify whether the morphology of blastocysts has notable indicators other than the Gardner criteria.

Methods

To find such indicators, we compared blastocysts that showed elevated human chorionic gonadotropin (hCG) levels after transplantation (hCG-positive group; n = 129) and those that did not (hCG-negative group; n = 105) using principal component analysis of pixel brightness of the images.

Results

The comparison revealed that the hCG-positive group had grainy morphology and the hCG-negative group had non-grainy morphology. Classification of the blastocysts by this indicator did not make a difference in Gardner score. Interestingly, all embryos with ≥20% fragmentation were non-grainy. The visual classification based on this analysis was significantly more accurate than the prediction of implantation using the Gardner score ≥3BB. As graininess can be used in combination with the Gardner score, this indicator will enhance current reproductive technologies.
A Novel Approach in Understanding and Retaining the Subject Concepts among Medical Undergraduates using Treasure Hunt Competition as a Tool: A Quasi-experimental Study
Authors: Manikkoth Shyamjith , Deepa B , Raj Prajna V , Vangalapati Bheemesh , Urval Rathnakar P , Vadakedom Suresh , Radhakrishnan Sajith Kumar
Published: May 2022

Introduction: There is a need to incorporate innovative teaching methods other than conventional didactic lectures to generate interest of medical undergraduates in learning Pharmacology. Game-based Learning (GBL) is a new strategy in medical education that can create a fun based atmosphere for learning. Aim: To assess the effectiveness of GBL as a tool in learning process and in memory retention of the knowledge acquired in Pharmacology using treasure hunt competition. Materials and Methods: The quasi-experimental study was conducted on 4th semester MBBS students of Kanachur Institute of Medical Sciences, Mangaluru, Karnataka, India, from February 2019 to March 2019, as a part of the Advanced Course in Medical Education [ACME] project work, Medical Council of India. Entire phase II students (N=150) were included in the study. Students were divided into the GBL group and the Facilitated Learners (FL) group. Both groups were exposed to their respective GBL and FL based learning. Before and after the respective GBL and FL sessions, a pretest and two posttest multiple choice questions based tests were conducted. The second post-test was conducted one month later as a surprise one. Thereafter, a questionnaire was given to pen down the perceptions about GBL. Pretest and post-test marks were analysed by one-way Analysis of Variance (ANOVA) followed by the Tukey-Kramer test. Perceptions about GBL were entered in percentage. Results: The mean scores of the GBL group were significantly more (p-value<0.001) as compared to the FL group in both the post-tests. In their feedback about GBL, the students appreciated the usefulness of this innovative way of learning Pharmacology. Conclusion: The GBL is an effective tool to teach pharmacology to medical undergraduates.
Mode of Entry Strategy on SMEs Internationalization in East Java: A Review of Literature
Authors: Rochayatun Sulis , . Sudarmiatin , Bidin Rozmiza
Published: May 2022

This study review the internationalization of SMEs in East Java from a literature and empirical perspective with the aim of providing in-depth knowledge based on the existing literature and supported by empirical data generated from previous research. This study uses content analysis of current theories and models coupled with empirical analysis of the internationalization studies of SMEs that have been carried out. There are several theories and models, such as the internalization theory, the eclectic paradigm, the Upsala model, the network perspective that connects the internationalization strategy of SMEs in East Java, and several modes of entry for internationalization. The theory is based on the basic resource-based view and network theory. Documented evidence shows that the internationalization strategy of SMEs in East Java still has many obstacles and challenges. Theoretically, the internationalization strategy related to the mode of entry leads to networking. Empirical data supports that the strategy mostly carried out by SMEs in East Java is networking independently. The results of this study are expected to contribute ideas for policymakers, in this case, the government, to play a more active role with long-term strategies for the success of the internationalization of SMEs in East Java.
Problems Encountered by BEEd Teachers and Students of Apayao State College in Using Modular Distance Learning Modality: Basis for Intervention
Authors: Sanchez Marfred T. , Tumaneng Ruth A. , Español Shane Pearl Lae S.
Published: May 2022

This study used a descriptive phenomenological approach to identify the problems encountered by teachers and students in implementing modular distance learning, as well as the possible solutions to the identified problems. The study was conducted among the teachers and students of Bachelor of Elementary Education Department (BEEd) of Apayao State College – Luna Campus. Four (4) BEEd program mainstay teachers and ten (10) BEEd students were approached to request their voluntary involvement as key participants to the study. The participants were chosen using convenience sampling and then interviewed individually via video conference to learn more about their experiences as a data-gathering tool. Data were analyzed using a thematic analysis approach to find any patterns in the participants’ responses by transcribing, organizing, and coding. Findings revealed that teachers identified four (4) themes of problems related to the preparation of printed learning materials; management in the distribution of printed learning materials; retrieval of students’ activities and outputs; and checking of students’ activities and outputs. Students also identified two (2) themes of problems they had in using modular distance learning that is related to the submission of their activities and outputs, as well as their capability to learn independently. School administrators can use the findings of this study to develop interventions, programs, and activities to address issues in the implementation of the modular distance learning modality.
Effect of Agricultural Cooperative Membership on Willingness to Pay for Non-fatal Risk Reduction from COVID-19
Authors: Coker A. A. A. , Yusuf T. , Oseghale A. I. , Oladele A. O. , Sule B. A.
Published: May 2022

The recurring nature of the COVID-19 pandemic and the recent discovery of the Omicron variant in Nigeria, coupled with concerns about the specific roles and contributions of social institutions in redressing the spread of the virus, prompted this study. Thus, the study determined the willingness to pay for health risk reduction from Corona Virus (COVID-19); estimated the value of statistical case (VSC) and ascertained the effects of cooperative membership on the willingness to pay (WTP) for COVID-19 morbidity health risk reduction. Multi-stage sampling technique was deployed in selecting 149 cooperative and 130 non-cooperative members for the study, in Edu and Patigi Local Government Areas of Kwara State, Nigeria. To reach its conclusion, descriptive statistics, Levene’s test, t-test, chi-square, Probit analysis, propensity score matching, WTP and the value of statistical case were employed for data analysis. The study revealed that the typical cooperative member is willing to pay N1,638 per farming season to decrease his or her chance of falling sick from COVID-19 or averting non-fatal cases of COVID-19 by 1 in 10,000. In addition, the propensity score matching (PSM) estimation indicated that agricultural cooperative societies had effect on members, with the average member willing to pay N561.32 per season higher than the non-members. Arising from these results, it becomes imperative to consider integrating cooperative societies as complementary instrument for the prevention and control of COVID-19 pandemic. The estimated VSC further provides pecuniary basis and policy guidance for efficient allocation of resources for the mitigation and control of COVID-19.
Mathematics in the Classroom: A Survey of Teachers' Opinions on the Use of Information and Communication Technologies (ICTs) in Teaching and Learning
Authors: Adams Alfred Kofi
Published: May 2022

Aim: The purpose of this study was to look into how school mathematics teachers use ICT in their classrooms, as well as the perceived barriers and challenges to ICT integration in mathematics classrooms.

Study Design: The research was conducted using a descriptive cross-sectional survey research approach.

Methodology: A cluster sampling strategy was utilized to pick 120 teachers from public schools in the keta municipality of the Volta region for this study. The questionnaire was returned by 105 teachers, with an 87.5 percent response rate, and descriptive statistics were utilized to analyze the data. 72 percent of the 105 teachers were males and 28 percent were females.

Results: According to the findings, mathematics teachers use ICT in their classrooms to a very limited extent. Some mathematics teachers, on the other hand, frequently utilise ICT for common computer applications, including obtaining information on the internet for teaching, networking with colleagues and students, sending emails, and producing lesson notes etc. Respondents lacked proper training and access to instructional technologies, according to the findings.

The lack of printers and presentation equipment in schools, according to respondents, may hinder their ability to integrate ICT into the teaching and learning process.

Conclusions: Because of a lack of technical know-how and inadequate ICT tools, most mathematics teachers do not use ICT in their classroom. Teachers who have minimal experience with ICT, on the other hand, prefer to utilise it for non-teaching purposes.
Effect of Planting Methods and Weed Management Practices on Growth and Yield of Paddy (Oryza sativa L.)
Authors: Angel Boddu Krupa Blessy , Singh Shikha
Published: May 2022

The trial was conducted at Crop Research Farm, Department of Agronomy of Naini Agricultural Institute, SHUATS, Prayagraj (U.P), during Kharif 2021.The experiment was bifactorial (two factors) which consists of three different planting methods i.e., Direct seeded rice, Transplanted rice and SRI method, and three different weed management practices i.e., Hand weeding (twice), Oxadiazon 25 EC (as Pre emergence) at 250g/L (2L/ha) and Pyrazosulfuron ethyl 10% WP at 20g/ha (as Post Emergence) and a control plot laid out in randomized block design with ten different treatment combinations which is replicated thrice. The results revealed that at harvest significantly, higher growth attributes like plant height (117.28 cm), Number of tillers (38), plant dry weight (56.36 g/hill) at harvest is recorded in treatment number 7 with a combination of SRI method of planting and Hand weeding twice at critical crop weed competition. Significantly, higher yield attributes like number of effective tillers/ hill (35), number of panicles/ plant (44), number of grains per panicle (216.6), test weight (25 g), grain yield (5.1 t/ha) and straw yield (8.1 t/ha) was highest in the same treatment. From the experiment it can be concluded that treatment 7 where SRI method of planting and hand weeding twice during critical crop weed competition was considered as best treatment combination with maximum effective tillers/hill, number of panicles/plant,   number of grains per panicle, test weight, grain yield and straw yield i.e., all the yield attributes.