bluuebunny/crossref_metadata_2025 huggingface dataset:
Wind, Solar, and Photovoltaic Renewable Energy Systems with and without Energy Storage Optimization: A Survey of Advanced Machine Learning and Deep Learning Techniques
Authors: Abualigah Laith , Zitar Raed Abu , Almotairi Khaled H. , Hussein Ahmad MohdAziz , Abd Elaziz Mohamed , Nikoo Mohammad Reza , Gandomi Amir H.
Published: January 2022

Nowadays, learning-based modeling methods are utilized to build a precise forecast model for renewable power sources. Computational Intelligence (CI) techniques have been recognized as effective methods in generating and optimizing renewable tools. The complexity of this variety of energy depends on its coverage of large sizes of data and parameters, which have to be investigated thoroughly. This paper covered the most resent and important researchers in the domain of renewable problems using the learning-based methods. Various types of Deep Learning (DL) and Machine Learning (ML) algorithms employed in Solar and Wind energy supplies are given. The performance of the given methods in the literature is assessed by a new taxonomy. This paper focus on conducting comprehensive state-of-the-art methods heading to performance evaluation of the given techniques and discusses vital difficulties and possibilities for extensive research. Based on the results, variations in efficiency, robustness, accuracy values, and generalization capability are the most obvious difficulties for using the learning techniques. In the case of the big dataset, the effectiveness of the learning techniques is significantly better than the other computational methods. However, applying and producing hybrid learning techniques with other optimization methods to develop and optimize the construction of the techniques is optionally indicated. In all cases, hybrid learning methods have better achievement than a single method due to the fact that hybrid methods gain the benefit of two or more techniques for providing an accurate forecast. Therefore, it is suggested to utilize hybrid learning techniques in the future to deal with energy generation problems.
Flight Simulator’s Energy Consumption Depending on the Conditions of the Air Operation
Authors: Gołębiewski Michał , Galant-Gołębiewska Marta , Jasiński Remigiusz
Published: January 2022

Protection of the natural environment is a key activity driving development in the transport discipline today. The use of simulators to train civil aviation pilots provides an excellent opportunity to maintain the balance between efficiency and limit the negative impact of transport on the environment. Therefore, we decided to determine the impact of selected simulations of air operations on energy consumption. The aim of the research was to determine the energy consumption of the flight simulator depending on the type of flight operation and configuration used. We also decided to compare the obtained result with the energy consumption of an aircraft of a similar class, performing a similar aviation operation and other means of transport. In order to obtain the results, a research plan was proposed consisting of 12 scenarios differing in the simulated aircraft model, weather conditions and the use of the simulator motion platform. In each of the scenarios, energy consumption was measured, taking into account the individual components of the simulator. The research showed that the use of a flight simulator has a much smaller negative impact on the natural environment than flying in a traditional plane. Use of a motion platform indicated a change in energy consumption of approximately 40% (in general, flight simulator configuration can change energy consumption by up to 50%). The deterioration of weather conditions during the simulation caused an increase in energy consumption of 14% when motion was disabled and 18% when motion was enabled. Energy consumption in the initial stages of pilot training can be reduced by 97% by using flight simulators compared to aircraft training.
Thermal Analysis and Optimization of the Phase Diagram of the Cu-Ag Sulfide System
Authors: Tesfaye Fiseha , Lindberg Daniel , Sukhomlinov Dmitry , Taskinen Pekka , Hupa Leena
Published: January 2022

Thermal stabilities of selected ternary phases of industrial interest in the Ag-Cu-S system have been studied by the calorimetric and electromotive force techniques. The ternary compounds Ag1.2Cu0.8S (mineral mackinstryite) and AgCuS (mineral stromeyerite) were equilibrated through high-temperature reaction of the pure Cu2S and Ag2S in an inert atmosphere. The synthesized single solid sample constituting the two ternary phases was ground into fine powders and lightly pressed into pellets before calorimetric measurements. An electrochemical cell incorporating the two equilibrated phase and additional CuS as a cathode material was employed. The measurement results obtained with both techniques were analyzed and thermodynamic properties in the system have been determined and compared with the available literature values. Enthalpy of fusion data of the Ag-richer solid solution (Ag,Cu)2S have also been determined directly from the experimental data for the first time. The thermodynamic quantities determined in this work can be used to calculate thermal energy of processes involving the Ag-Cu-S-ternary phases. By applying the obtained results and the critically evaluated literature data, we have developed a thermodynamic database. The self-developed database was combined with the latest pure substances database of the FactSage software package to model the phase diagram of the Ag2S-Cu2S system.
The Development and Issues of Energy-ICT: A Review of Literature with Economic and Managerial Viewpoints
Authors: Hu Jin-Li , Chen Yi-Chou , Yang Ya-Po
Published: January 2022

This paper reviews the economic and managerial literature on the relationship between energy-ICT and the development of the green energy economy. It is summarized that there are four lines of existing literature on energy-ICT: cost and benefit analysis, fair competition issues, cybersecurity issues, and promotion policy issues. Even though ICT is energy-consuming, most of the existing empirical studies support the idea that energy-ICT has net positive effects on energy savings, energy efficiency improvement, emission reduction, and economic growth at both enterprise and economy-wide levels. Energy-ICT equips the platform operator with higher bargaining power, such that a governance mechanism to assure the fair access right of each entitled participant is required. A smarter energy-ICT network also becomes riskier, and hence the cybersecurity protection is more important than before. Future research and development opportunities remain on these issues of the fair competition, cybersecurity, and promotion policy of energy-ICT.
The Role of Large Cities in the Development of Low-Carbon Economy—The Example of Poland
Authors: Standar Aldona , Kozera Agnieszka , Jabkowski Dawid
Published: January 2022

The main objective of the article is to evaluate the investment activity of large cities in Poland in the area of developing a low-carbon economy in 2014–2020, co-financed by European Union funds. This article poses several research questions, namely: Do large cities with environmental problems actively obtain EU funding to develop a low-carbon economy? What are the main socio-economic and environmental determinants of the level of the EU funding absorption among large cities in the research area? The empirical research was conducted on the basis of the data from the Ministry of Investment and Economic Development in Poland, which is responsible for the implementation of cohesion policy funds and from the Local Data Bank of Statistics Poland. Under the 2014–2020 perspective, 223 such projects have been implemented for a total of PLN 21 billion (EUR 4.74 billion). The projects focused on: transportation, electricity, gaseous fuels, steam, hot water and air for air conditioning systems, and environmental and climate change activities. In terms of both the number and the value of EU funds spent, great variation has been observed. Analysis of the correlation relationships showed a highly positive correlation between selected indicators of investment activity in the field of low-carbon economy co-financed by EU funds (especially taking into account the value of investments per area) and socio-economic indicators of Polish metropolises. Metropolises with high demographic, economic, and financial potential have proven to be more effective beneficiaries. Interestingly, no correlation was found between investment activity in the low-carbon economy and the level of environment pollution in large cities. This means that, unfortunately, pro-environmental activities depend on the state of finances of the cities, and not necessarily on the actual needs, even taking into account the fact that the EU covers a large proportion of the costs.
Influence of Topographic Conditions on Teak Growth Performance in Mountainous Landscapes of Lao PDR
Authors: Vongkhamho Simone , Imaya Akihiro , Yamamoto Kazukiyo , Takenaka Chisato , Yamamoto Hiroyuki
Published: January 2022

Teak is a globally valuable hardwood tree species, as its growth performance is important for timber productivity. The purpose of this study was to establish an effective management system for teak plantations in the Lao PDR. Using diameter at breast height (DBH) and height growth as significant indicators of growth performance, we investigated the relationship between tree growth curve parameters of teak and topographic conditions. Stem analysis data for 81 sample trees (three trees selected in canopy trees with predominant height in each plot) were examined for growth performance using the Mitscherlich growth function. The results of Spearman’s partial rank correlation indicated that the upper limits of DBH and tree height growth had significant negative correlations with the slope gradient and stand density. The curvature of DBH and tree height growth curves showed significant positive correlations with the slope form. Moreover, the elevation and slope gradient showed significant negative correlations with the curvature of tree height growth curve. However, the time lag of DBH growth showed a significant negative correlation with the slope position, while the slope gradient was positively correlated with the time lag of tree height growth. These results suggest that teak planted at lower slopes has faster growth rates and that there is an interaction with the gentle concave slope of this area.
Species Mixing Proportion and Aridity Influence in the Height–Diameter Relationship for Different Species Mixtures in Mediterranean Forests
Authors: Rodríguez de Prado Diego , Riofrío Jose , Aldea Jorge , McDermott James , Bravo Felipe , Herrero de Aza Celia
Published: January 2022

Estimating tree height is essential for modelling and managing both pure and mixed forest stands. Although height–diameter (H–D) relationships have been traditionally fitted for pure stands, attention must be paid when analyzing this relationship behavior in stands composed of more than one species. The present context of global change makes also necessary to analyze how this relationship is influenced by climate conditions. This study tends to cope these gaps, by fitting new H–D models for 13 different Mediterranean species in mixed forest stands under different mixing proportions along an aridity gradient in Spain. Using Spanish National Forest Inventory data, a total of 14 height–diameter equations were initially fitted in order to select the best base models for each pair species-mixture. Then, the best models were expanded including species proportion by area (mi) and the De Martonne Aridity Index (M). A general trend was found for coniferous species, with taller trees for the same diameter size in pure than in mixed stands, being this trend inverse for broadleaved species. Regarding aridity influence on H–D relationships, humid conditions seem to beneficiate tree height for almost all the analyzed species and species mixtures. These results may have a relevant importance for Mediterranean coppice stands, suggesting that introducing conifers in broadleaves forests could enhance height for coppice species. However, this practice only should be carried out in places with a low probability of drought. Models presented in our study can be used to predict height both in different pure and mixed forests at different spatio-temporal scales to take better sustainable management decisions under future climate change scenarios.
Global Analysis of the WOX Transcription Factor Gene Family in Populus × xiaohei T. S. Hwang et Liang Reveals Their Stress−Responsive Patterns
Authors: Li Yue , Jin Chunhui , Liu Yuting , Wang Lili , Li Fangrui , Wang Bo , Liu Guifeng , Jiang Jing , Li Huiyu
Published: January 2022

The WUSCHEL−related homeobox (WOX) family is a group of plant−specific transcription factors that play important regulatory roles in embryo formation, stem cell stability, and organogenesis. To date, there are few studies on the molecular mechanisms involved in this family of genes in response to stress. Thus, in this study, eight WOX genes were obtained from an endemic Chinese resilient tree species, Populus × xiaohei T. S. Hwang et Liang. Bioinformatic analysis showed that the WOX genes all contained a conserved structural domain consisting of 60 amino acids, with some differences in physicochemical properties. Phylogenetic analysis revealed that WOX members were divided into three evolutionary clades, with four, one, and three members in the ancient, intermediate, and modern evolutionary clades, respectively. The conserved structural domain species as well as the organization and gene structure of WOX genes within the same subfamily were highly uniform. Chromosomal distribution and genome synteny analyses revealed seven segmental−duplicated gene pairs among the PsnWOX gene family that were mainly under purifying selection conditions. Semi−quantitative interpretation (SQ−PCR) analysis showed that the WOX gene was differentially expressed in different tissues, and it was hypothesized that the functions performed by different members were diverse. The family members were strongly and differentially expressed under CdCl2, NaCl, NaHCO3, and PEG treatments, suggesting that WOX genes function in various aspects of abiotic stress defense responses. These results provide a theoretical basis for investigating the morphogenetic effects and abiotic stress responses of this gene family in woody plants.
The Effects of Plant and Soil Characteristics on Partitioning Different Rainfalls to Soil in a Subtropical Chinese Fir Forest Ecosystem
Authors: Zhang Ying , Zhang Beibei , Xu Qing , Gao Deqiang , Xu Wenbin , Ren Ranran , Jiang Jing , Wang Silong
Published: January 2022

The climate-induced changes in soil water patterns pose a serious threat to subtropical plantations. Mixed species stands have been advocated as an efficient way to enhance ecosystem stability. However, little is known about their possible impact on the soil water-holding capacity in the subtropics. In this study, we employed a stable hydrogen isotope to assess the contribution of rainfall to soil water (CRSW) in a pure Chinese fir (Cunninghamia lanceolata) plantation and in two mixtures of Chinese fir with Cinnamomum camphora or with Alnus cremastogyne after three different magnitudes of rainfall events in subtropical China. Furthermore, we used structure equation modeling (SEM) to quantify the relative importance of vegetation and soil properties on the CRSW. The results indicated that the CRSW did not differ among these three Chinese fir plantations after light rainfall, whereas the CRSW of moderate and heavy rainfall to soil water were 15.95% and 26.06% higher in Chinese fir plantation with Cinnamomum camphora, and 22.67% and 22.93% higher in Chinese fir plantation with Alnus cremastogyne than that in the pure Chinese fir plantation, respectively. SEM analysis showed that the vegetation biomass and soil properties significantly affected the CRSW following light rainfall, but the soil properties were the most important factors influencing the CRSW under moderate and heavy rainfall. Our findings demonstrate that the mixed conifer–broad-leaved plantation is a more effective strategy for improving the soil water-holding capacity than the pure conifer plantation in subtropical regions, which is conducive to coping with the frequent seasonal droughts and extreme precipitation events.
A Compressible Turbulence Model for Pressure—Strain
Authors: Khlifi Hechmi , Bourehla Adnen
Published: January 2022

This work focuses on the performance and validation of compressible turbulence models for the pressure-strain correlation. Considering the Launder Reece and Rodi (LRR) incompressible model for the pressure-strain correlation, Adumitroaie et al., Huang et al., and Marzougui et al., used different modeling approaches to develop turbulence models, taking into account compressibility effects for this term. Two numerical coefficients are dependent on the turbulent Mach number, and all of the remaining coefficients conserve the same values as in the original LRR model. The models do not correctly predict the compressible turbulence at a high-speed shear flow. So, the revision of these models is the major aim of this study. In the present work, the compressible model for the pressure-strain correlation developed by Khlifi−Lili, involving the turbulent Mach number, the gradient, and the convective Mach numbers, is used to modify the linear mean shear strain and the slow terms of the previous models. The models are tested in two compressible turbulent flows: homogeneous shear flow and the newly developed plane mixing layers. The predicted results of the proposed modifications of the Adumitroaie et al., Huang et al., and Marzougui et al., models and of its universal versions are compared with direct numerical simulation (DNS) and experiment data. The results show that the important parameters of compressibility in homogeneous shear flow and in the mixing layers are well predicted by the proposal models.
Analysis of the Shear-Thinning Viscosity Behavior of the Johnson–Segalman Viscoelastic Fluids
Authors: Bodnár Tomáš , Sequeira Adélia
Published: January 2022

This paper presents a numerical comparison of viscoelastic shear-thinning fluid flow using a generalized Oldroyd-B model and Johnson–Segalman model under various settings. Results for the standard shear-thinning generalization of Oldroyd-B model are used as a reference for comparison with those obtained for the same flow cases using Johnson–Segalman model that has specific adjustment of convected derivative to assure shear-thinning behavior. The modeling strategy is first briefly described, pointing out the main differences between the generalized Oldroyd-B model (using the Cross model for shear-thinning viscosity) and the Johnson–Segalman model operating in shear-thinning regime. Then, both models are used for blood flow simulation in an idealized stenosed axisymmetric vessel under different flow rates for various model parameters. The simulations are performed using an in-house numerical code based on finite-volume discretization. The obtained results are mutually compared and discussed in detail, focusing on the qualitative assessment of the most distinct flow field differences. It is shown that despite all models sharing the same asymptotic viscosities, the behavior of the Johnson–Segalman model can be (depending on flow regime) quite different from the predictions of the generalized Oldroyd-B model.
The Effect of Microwave Irradiation on the Representation and Growth of Moulds in Nuts and Almonds
Authors: Popelářová Eva , Vlková Eva , Švejstil Roman , Kouřimská Lenka
Published: January 2022

Microwave (MW) irradiation is a non-destructive method that can be applied as an alternative method to inhibit the growth of microorganisms. The present study evaluated the effect of MW irradiation on the occurrence of moulds in nuts and almonds. Samples of unshelled natural almonds, pistachios, and in-shell peanuts were treated with different doses of MW irradiation (2400–4000 W). The effect of MW irradiation on mould counts was evaluated by cultivating immediately after irradiation and after 3 and 6 months of storage. The most represented genera in all analysed samples were Aspergillus (68%), Penicillium (21%), and a small amount of Cladosporium (3%). Mould numbers significantly decreased after MW treatment. The treatments with MW irradiations at 3000 and 4000 W significantly reduced the mould colony counts, and their effect persisted during storage; irradiation at 2400 W was partially effective. The strongest effect of MW irradiation was observed in in-shell peanuts. MW irradiation seems to be a promising method for maintaining the microbiological quality of nuts.
Effects of Thickness Fraction Process on Physicochemical Properties, Cooking Qualities, and Sensory Characteristics of Long-Grain Rice Samples
Authors: Jarma Arroyo Sara , Siebenmorgen Terry , Seo Han-Seok
Published: January 2022

A process of removing thinner kernels of rough rice, i.e., thickness fraction process, has been suggested as a method for increasing milling yields in the rice industry. This study aimed at determining whether physicochemical properties, cooking qualities, and sensory characteristics of rice samples could be changed by the addition of a thickness fraction into the rice process stream. Each of four long-grain rice cultivar lots was assigned into two groups: unfractionated and thickness-fractionated. For the thickness-fractionated group, thin rice kernels (<1.9 mm) of rough rice were discarded from unfractionated rice samples. Unfractionated and thickness-fractionated rice samples were compared with respect to physicochemical properties, cooking qualities, and sensory characteristics. The results showed that the removal of such thin kernels decreased the breakage and chalkiness rates and increased head rice yields. Fractionated rice samples exhibited lower amylose contents and crude protein contents but higher gelatinization temperatures than unfractionated rice samples. While the optimum cooking duration and width–expansion ratios of thickness-fractionated rice samples were higher than those of unfractionated ones, there was a negligible impact of the thickness fraction process on sensory characteristics of long-grain rice samples. In conclusion, the thickness fraction process affects physicochemical properties and cooking qualities more than the sensory characteristics of rice samples.
On Global Convergence of Third-Order Chebyshev-Type Method under General Continuity Conditions
Authors: Mallawi Fouad Othman , Behl Ramandeep , Maroju Prashanth
Published: January 2022

There are very few papers that talk about the global convergence of iterative methods with the help of Banach spaces. The main purpose of this paper is to discuss the global convergence of third order iterative method. The convergence analysis of this method is proposed under the assumptions that Fréchet derivative of first order satisfies continuity condition of the Hölder. Finally, we consider some integral equation and boundary value problem (BVP) in order to illustrate the suitability of theoretical results.
OTP970 Is Required for RNA Editing of Chloroplast ndhB Transcripts in Arabidopsis thaliana
Authors: Fu Mei , Lin Xiaona , Zhou Yining , Zhang Chunmei , Liu Bing , Feng Dongru , Wang Jinfa , Wang Hongbin , Jin Honglei
Published: January 2022

RNA editing is essential for compensating for defects or mutations in haploid organelle genomes and is regulated by numerous trans-factors. Pentatricopeptide repeat (PPR) proteins are the prime factors that are involved in RNA editing; however, many have not yet been identified. Here, we screened the plastid-targeted PLS-DYW subfamily of PPR proteins belonging to Arabidopsis thaliana and identified ORGANELLE TRANSCRIPT PROCESSING 970 (OTP970) as a key player in RNA editing in plastids. A loss-of-function otp970 mutant was impaired in RNA editing of ndhB transcripts at site 149 (ndhB-C149). RNA-immunoprecipitation analysis indicated that OTP970 was associated with the ndhB-C149 site. The complementation of the otp970 mutant with OTP970 lacking the DYW domain (OTP970∆DYW) failed to restore the RNA editing of ndhB-C149. ndhB gene encodes the B subunit of the NADH dehydrogenase-like (NDH) complex; however, neither NDH activity and stability nor NDH-PSI supercomplex formation were affected in otp970 mutant compared to the wild type, indicating that alteration in amino acid sequence is not necessary for NdhB function. Together, these results suggest that OTP970 is involved in the RNA editing of ndhB-C149 and that the DYW domain is essential for its function.
Genome-Wide Analysis in Drosophila Reveals the Genetic Basis of Variation in Age-Specific Physical Performance and Response to ACE Inhibition
Authors: Gabrawy Mariann M. , Khosravian Nick , Morcos George S. , Morozova Tatiana V. , Jezek Meagan , Walston Jeremy D. , Huang Wen , Abadir Peter M. , Leips Jeff
Published: January 2022

Despite impressive results in restoring physical performance in rodent models, treatment with renin–angiotensin system (RAS) inhibitors, such as Lisinopril, have highly mixed results in humans, likely, in part, due to genetic variation in human populations. To date, the genetic determinants of responses to drugs, such as RAS inhibitors, remain unknown. Given the complexity of the relationship between physical traits and genetic background, genomic studies which predict genotype- and age-specific responses to drug treatments in humans or vertebrate animals are difficult. Here, using 126 genetically distinct lines of Drosophila melanogaster, we tested the effects of Lisinopril on age-specific climbing speed and endurance. Our data show that functional response and sensitivity to Lisinopril treatment ranges from significant protection against physical decline to increased weakness depending on genotype and age. Furthermore, genome-wide analyses led to identification of evolutionarily conserved genes in the WNT signaling pathway as being significantly associated with variations in physical performance traits and sensitivity to Lisinopril treatment. Genetic knockdown of genes in the WNT signaling pathway, Axin, frizzled, nemo, and wingless, diminished or abolished the effects of Lisinopril treatment on climbing speed traits. Our results implicate these genes as contributors to the genotype- and age-specific effects of Lisinopril treatment and because they have orthologs in humans, they are potential therapeutic targets for improvement of resiliency. Our approach should be widely applicable for identifying genomic variants that predict age- and sex-dependent responses to any type of pharmaceutical treatment.
Gene Network of Susceptibility to Atypical Femoral Fractures Related to Bisphosphonate Treatment
Authors: Garcia-Giralt Natalia , Roca-Ayats Neus , Abril Josep F , Martinez-Gil Nuria , Ovejero Diana , Castañeda Santos , Nogues Xavier , Grinberg Daniel , Balcells Susanna , Rabionet Raquel
Published: January 2022

Atypical femoral fractures (AFF) are rare fragility fractures in the subtrocantheric or diaphysis femoral region associated with long-term bisphosphonate (BP) treatment. The etiology of AFF is still unclear even though a genetic basis is suggested. We performed whole exome sequencing (WES) analysis of 12 patients receiving BPs for at least 5 years who sustained AFFs and 4 controls, also long-term treated with BPs but without any fracture. After filtration and prioritization of rare variants predicted to be damaging and present in genes shared among at least two patients, a total of 272 variants in 132 genes were identified. Twelve of these genes were known to be involved in bone metabolism and/or AFF, highlighting DAAM2 and LRP5, both involved in the Wnt pathway, as the most representative. Afterwards, we intersected all mutated genes with a list of 34 genes obtained from a previous study of three sisters with BP-related AFF, identifying nine genes. One of these (MEX3D) harbored damaging variants in two AFF patients from the present study and one shared among the three sisters. Gene interaction analysis using the AFFNET web suggested a complex network among bone-related genes as well as with other mutated genes. BinGO biological function analysis highlighted cytoskeleton and cilium organization. In conclusion, several genes and their interactions could provide genetic susceptibility to AFF, that along with BPs treatment and in some cases with glucocorticoids may trigger this so feared complication.
Aspects of Prevention of Urinary Tract Infections Associated with Urinary Bladder Catheterisation and Their Implementation in Nursing Practice
Authors: Krocová Jitka , Prokešová Radka
Published: January 2022

In the case of the prevention of catheter-associated urinary tract infections (CAUTI) related to healthcare provision, high-quality and comprehensively provided nursing care is essential. Implementation of preventive strategies is based on recommended procedures, and the introduction of whole sets of measures has been shown to be effective. The objective of this research is to find out whether the providers of acute bed care have implemented the steps of CAUTI prevention, and specifically which measures leading to improved quality of care in the area of urinary infections are already in place. To determine this, we carried out quantitative research. Data were collected using a questionnaire-based investigation; we used two non-standardised and one standardised questionnaire, and the respondents were general nurses in management positions (n = 186). The results revealed that result-related CAUTI indicators are monitored by only one-third of the respondents, and records of catheterisation indication are not kept by 17.3% of general nurses. The results of the research showed deficiencies in the monitoring of CAUTI outcome and process indicators, and a weakness of the implemented preventive measures is the maintenance of catheterisation documentation. Periodic CAUTI prevention training is not implemented as recommended. It is positive that there are well-working teams of HAI prevention experts in hospitals.
The Artificial Intelligence in Digital Radiology: Part 2: Towards an Investigation of acceptance and consensus on the Insiders
Authors: Di Basilio Francesco , Esposisto Gianluca , Monoscalco Lisa , Giansanti Daniele
Published: January 2022

Background. The study deals with the introduction of the artificial intelligence in digital radiology. There is a growing interest in this area of scientific research in acceptance and consensus studies involving both insiders and the public, based on surveys focused mainly on single professionals. Purpose. The goal of the study is to perform a contemporary investigation on the acceptance and the consensus of the three key professional figures approaching in this field of application: (1) Medical specialists in image diagnostics: the medical specialists (MS)s; (2) experts in physical imaging processes: the medical physicists (MP)s; (3) AI designers: specialists of applied sciences (SAS)s. Methods. Participants (MSs = 92: 48 males/44 females, averaged age 37.9; MPs = 91: 43 males/48 females, averaged age 36.1; SAS = 90: 47 males/43 females, averaged age 37.3) were properly recruited based on specific training. An electronic survey was designed and submitted to the participants with a wide range questions starting from the training and background up to the different applications of the AI and the environment of application. Results. The results show that generally, the three professionals show (a) a high degree of encouraging agreement on the introduction of AI both in imaging and in non-imaging applications using both standalone applications and/or mHealth/eHealth, and (b) a different consent on AI use depending on the training background. Conclusions. The study highlights the usefulness of focusing on both the three key professionals and the usefulness of the investigation schemes facing a wide range of issues. The study also suggests the importance of different methods of administration to improve the adhesion and the need to continue these investigations both with federated and specific initiatives.
Artificial Intelligence Analysis of Gene Expression Predicted the Overall Survival of Mantle Cell Lymphoma and a Large Pan-Cancer Series
Authors: Carreras Joaquim , Nakamura Naoya , Hamoudi Rifat
Published: January 2022

Mantle cell lymphoma (MCL) is a subtype of mature B-cell non-Hodgkin lymphoma characterized by a poor prognosis. First, we analyzed a series of 123 cases (GSE93291). An algorithm using multilayer perceptron artificial neural network, radial basis function, gene set enrichment analysis (GSEA), and conventional statistics, correlated 20,862 genes with 28 MCL prognostic genes for dimensionality reduction, to predict the patients’ overall survival and highlight new markers. As a result, 58 genes predicted survival with high accuracy (area under the curve = 0.9). Further reduction identified 10 genes: KIF18A, YBX3, PEMT, GCNA, and POGLUT3 that associated with a poor survival; and SELENOP, AMOTL2, IGFBP7, KCTD12, and ADGRG2 with a favorable survival. Correlation with the proliferation index (Ki67) was also made. Interestingly, these genes, which were related to cell cycle, apoptosis, and metabolism, also predicted the survival of diffuse large B-cell lymphoma (GSE10846, n = 414), and a pan-cancer series of The Cancer Genome Atlas (TCGA, n = 7289), which included the most relevant cancers (lung, breast, colorectal, prostate, stomach, liver, etcetera). Secondly, survival was predicted using 10 oncology panels (transcriptome, cancer progression and pathways, metabolic pathways, immuno-oncology, and host response), and TYMS was highlighted. Finally, using machine learning, C5 tree and Bayesian network had the highest accuracy for prediction and correlation with the LLMPP MCL35 proliferation assay and RGS1 was made. In conclusion, artificial intelligence analysis predicted the overall survival of MCL with high accuracy, and highlighted genes that predicted the survival of a large pan-cancer series.
The Prevalence, Management and Impact of Dysmenorrhea on Medical Students’ Lives—A Multicenter Study
Authors: Sima Romina-Marina , Sulea Mihaela , Radosa Julia Caroline , Findeklee Sebastian , Hamoud Bashar Haj , Popescu Mihai , Gorecki Gabriel Petre , Bobircă Anca , Bobirca Florin , Cirstoveanu Catalin , Ples Liana
Published: January 2022

Introduction: Dysmenorrhea is defined as the presence of painful menstruation, and it affects daily activities in different ways. The aims of this study were to assess the prevalence and management of dysmenorrhea and to determine the impact of dysmenorrhea on the quality of life of medical students. Material and methods: The study conducted was prospective, analytical and observational and was performed between 7 November 2019 and 30 January 2020 in five university centers from Romania. The data was collected using an original questionnaire regarding menstrual cycles and dysmenorrhea. The information about relationships with family or friends, couples’ relationships and university activity helped to assess the effects of dysmenorrhea on quality of life. The level of significance was set at p < 0.05. Results: The study comprised 1720 students in total. The prevalence of dysmenorrhea was 78.4%. During their menstrual period, most female students felt more agitated or nervous (72.7%), more tired (66.9%), as if they had less energy for daily activities (75.9%) and highly stressed (57.9%), with a normal diet being difficult to achieve (30.0%). University courses (49.4%), social life (34.5%), couples’ relationships (29.6%), as well as relationships with family (21.4%) and friends (15.4%) were also affected, depending on the duration and intensity of the pain. Conclusion: Dysmenorrhea has a high prevalence among medical students and could affect the quality of life of students in several ways. During their menstrual period, most female students feel as if they have less energy for daily activities and exhibit a higher level of stress. The intensity of the symptoms varies considerably and, with it, the degree of discomfort it creates. Most student use both pharmacological and non-pharmacological methods to reduce pain (75.7%). University courses, social life, couples’ relationships, as well as relationships with family and friends are affected, depending on the duration and intensity of the pain.
Postcode Lottery in Healthcare? Findings from the Scottish National Comprehensive Geriatric Assessment in Secondary Care Audit 2019
Authors: Young Catriona , Donaldson Alison I. C. , McAlpine Christine H. , Locherty Marc , Wood Adrian D. , Myint Phyo Kyaw
Published: January 2022

Comprehensive Geriatric Assessment (CGA) is provided differently across Scotland. The Scottish Care of Older People (SCoOP) CGA Audit was a national audit conducted in 2019 to assess this variation in acute hospitals. Two versions of audit questionnaires about the provision of CGA were developed (one each for larger hospitals and remote/rural areas) and piloted. The questionnaires were sent to representatives from all hospitals in Scotland using the REDCap (Research Electronic Data Capture) system. The survey asked each service to provide information on CGA service delivery at the ‘front door’. The questionnaire was open for completion between February and July 2019. Of the 28 Scottish hospitals which receive acute admissions, we received information from 26 (92.9% response rate). Reporting sites included seven hospitals from remote and rural locations in the Scottish Highlands and Islands. Significant variations were observed across participating sites for all key aspects studied: dedicated frailty units, routes of admission, staffing, liaison with other services and rehabilitation provision. The 2019 SCoOP CGA audit highlights areas of CGA services that could be improved and variation in specialist CGA service access, structure and staffing at the front door across Scotland. Whether this variation has an impact on the outcomes of older people requires further evaluation.
Morphological and Molecular Characterization of Nothotylenchus medians and N. similis (Nematoda: Anguinidae) from Southern Alberta, Canada
Authors: Munawar Maria , Rahman Atta Ur , Castillo Pablo , Yevtushenko Dmytro P.
Published: January 2022

The nematode family, Anguinidae, is a diverse group of polyphagous nematodes, generally known as fungal feeders or parasites of aerial plant parts. Here, we present the morphological and molecular characterization of adult females of two Nothotylenchus species, N. medians and N. similis, along with host association and geographical distribution data of the genus. Both species are recorded as new reports from Canada and designated as reference populations for future studies. Morphological or morphometrical variation was not observed in the Canadian population of N. medians and N. similis, in comparison with the original description. Phylogenetic analyses based on 18S and D2–D3 of 28S genes placed both species within Anguinidae. Since the biology of the genus Nothotylenchus has not been rigorously characterized, the habitat and distribution information presented in this study will shed some light on the ecology of these nematodes. Notably, the detection of N. medians and N. similis in our nematode inventory survey indicates that considerable Nothotylenchus diversity is hidden in these soils. Consequently, increased surveys and more in-depth research are needed to explore the full diversity of anguinids inhabiting these cultivated areas.
Hydroponic Basil Production: Temperature Influences Volatile Organic Compound Profile, but Not Overall Consumer Preference
Authors: Walters Kellie J. , Lopez Roberto G.
Published: January 2022

Altering the growing temperature during controlled-environment production not only influences crop growth and development, but can also influence volatile organic compound (VOC) production and, subsequently, sensory attributes of culinary herbs. Therefore, the objectives of this study were to (1) quantify the influence of mean daily temperature (MDT) and daily light integral (DLI) on key basil phenylpropanoid and terpenoid concentrations, (2) determine if differences in sensory characteristics due to MDT and DLI influence consumer preference, and (3) identify the sweet basil attributes consumers prefer. Thus, 2-week-old sweet basil ‘Nufar’ seedlings were transplanted into deep-flow hydroponic systems in greenhouses with target MDTs of 23, 26, 29, 32, or 35 °C and DLIs of 7, 9, or 12 mol·m−2·d−1. After three weeks, the two most recently mature leaves were harvested for gas chromatography–mass spectrometry (GC–MS) and consumer sensory analysis. Panel evaluations were conducted through a sliding door with samples served individually while panelists answered Likert scale and open-ended quality attribute and sensory questions. The DLI did not influence VOC concentrations. Increasing MDT from 23 to 36 °C during production increased 1,8 cineole, eugenol, and methyl chavicol concentrations linearly and did not affect linalool concentration. The increases in phenylpropanoid (eugenol and methyl chavicol) were greater than increases in terpenoid (1,8 cineole) concentrations. However, these increases did not impact overall consumer or flavor preference. The MDT during basil production influenced appearance, texture, and color preference of panelists. Taken together, MDT during production influenced both VOC concentrations and textural and visual attribute preference of basil but did not influence overall consumer preference. Therefore, changing the MDT during production can be used to alter plant growth and development without significantly affecting consumer preference.
New Insights into the Roles of Osmanthus Fragrans Heat-Shock Transcription Factors in Cold and Other Stress Responses
Authors: Bin Jing , Zhu Meilin , Ding Huifen , Zai Zhouying , Shi Tingting , Wang Lianggui , Yang Xiulian , Yue Yuanzheng
Published: January 2022

Sweet osmanthus (Osmanthus fragrans) is an evergreen woody plant that emits a floral aroma and is widely used in the landscape and fragrance industries. However, its application and cultivation regions are limited by cold stress. Heat-shock transcription factor (HSF) family members are widely present in plants and participate in, and regulate, the defense processes of plants under various abiotic stress conditions, but now, the role of this family in the responses of O. fragrans to cold stress is still not clear. Here, 46 OfHSF members were identified in the O. fragrans genome and divided into three subfamilies on the basis of a phylogenetic analysis. The promoter regions of most OfHSFs contained many cis-acting elements involved in multiple hormonal and abiotic stresses. RNA-seq data revealed that most of OfHSF genes were differentially expressed in various tissues, and some OfHSF members were induced by cold stress. The qRT-PCR analysis identified four OfHSFs that were induced by both cold and heat stresses, in which OfHSF11 and OfHSF43 had contrary expression trends under cold stress conditions and their expression patterns both showed recovery tendencies after the cold stress. OfHSF11 and OfHSF43 localized to the nuclei and their expression patterns were also induced under multiple abiotic stresses and hormonal treatments, indicating that they play critical roles in responses to multiple stresses. Furthermore, after a cold treatment, transient expression revealed that the malondialdehyde (MDA) content of OfHSF11-transformed tobacco significantly increased, and the expression levels of cold-response regulatory gene NbDREB3, cold response gene NbLEA5 and ROS detoxification gene NbCAT were significantly inhibited, implying that OfHSF11 is a negative regulator of cold responses in O. fragrans. Our study contributes to the further functional characterization of OfHSFs and will be useful in developing improved cold-tolerant cultivars of O. fragrans.
Climate Change and Zoonoses: A Review of Concepts, Definitions, and Bibliometrics
Authors: Leal Filho Walter , Ternova Linda , Parasnis Sanika Arun , Kovaleva Marina , Nagy Gustavo J.
Published: January 2022

Climate change can have a complex impact that also influences human and animal health. For example, climate change alters the conditions for pathogens and vectors of zoonotic diseases. Signs of this are the increasing spread of the West Nile and Usutu viruses and the establishment of new vector species, such as specific mosquito and tick species, in Europe and other parts of the world. With these changes come new challenges for maintaining human and animal health. This paper reports on an analysis of the literature focused on a bibliometric analysis of the Scopus database and VOSviewer software for creating visualization maps which identifies the zoonotic health risks for humans and animals caused by climate change. The sources retained for the analysis totaled 428 and different thresholds (N) were established for each item varying from N 5 to 10. The main findings are as follows: First, published documents increased in 2009–2015 peaking in 2020. Second, the primary sources have changed since 2018, partly attributable to the increase in human health concerns due to human-to-human transmission. Third, the USA, the UK, Canada, Australia, Italy, and Germany perform most zoonosis research. For instance, sixty documents and only 17 countries analyzed for co-authorship analysis met the threshold led by the USA; the top four author keywords were “climate change”, “zoonosis”, “epidemiology”, and “one health;” the USA, the UK, Germany, and Spain led the link strength (inter-collaboration); the author keywords showed that 37 out of the 1023 keywords met the threshold, and the authors’ keyword’s largest node of the bibliometric map contains the following: infectious diseases, emerging diseases, disease ecology, one health, surveillance, transmission, and wildlife. Finally, zoonotic diseases, which were documented in the literature in the past, have evolved, especially during the years 2010–2015, as evidenced by the sharp augmentation of publications addressing ad-hoc events and peaking in 2020 with the COVID-19 outbreak.
Air Pollution in Poland: A 2022 Narrative Review with Focus on Respiratory Diseases
Authors: Nazar Wojciech , Niedoszytko Marek
Published: January 2022

According to the World Bank Group, 36 of the 50 most polluted cities in the European Union are in Poland. Thus, ambient air pollution and its detrimental health effects are a matter of immense importance in Poland. This narrative review aims to analyse current findings on air pollution and health in Poland, with a focus on respiratory diseases, including COVID-19, as well as the Poles’ awareness of air pollution. PubMed, Scopus and Google Scholar databases were searched. In total, results from 71 research papers were summarized qualitatively. In Poland, increased air pollution levels are linked to increased general and respiratory disease mortality rates, higher prevalence of respiratory diseases, including asthma, lung cancer and COVID-19 infections, reduced forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). The proximity of high traffic areas exacerbates respiratory health problems. People living in more polluted regions (south of Poland) and in the winter season have a higher level of air pollution awareness. There is an urgent need to reduce air pollution levels and increase public awareness of this threat. A larger number of multi-city studies are needed in Poland to consistently track the burden of diseases attributable to air pollution.