bluuebunny/crossref_metadata_2025 huggingface dataset:
Medikamentöse Therapie der Herzinsuffizienz mit verminderter Auswurffraktion
Authors: Wieser Monika , Rhyner Daniel , Martinelli Michele , Suter Thomas , Schnegg Bruno , Bösch Claudia , Wigger Olivier , Dobner Stephan , Hunziker Lukas
Published: August 2018

Zusammenfassung. Die medikamentöse Therapie der Herzinsuffizienz (HI) hat im Verlauf der letzten drei Dekaden grosse Fortschritte gemacht. Evidenz-basierte medikamentöse Therapien haben Überleben und Lebensqualität entscheidend verbessert. Die medikamentöse Stufentherapie der Herzinsuffizienz beginnt mit den Angiotensin-konvertierenden-Enzym Hemmern (ACEH) oder Angiotensin-Rezeptorblockern (ARB) und Betablockern, welche bei praktisch jedem Patienten mit einer Herzinsuffizienz und reduzierter Ejektionsfraktion indiziert sind. Fällt die linksventrikuläre Ejektionsfraktion unter 35 % und / oder persistieren die Symptome (NYHA II-IV) kommt zusätzlich ein Mineralokortikoidrezeptor-Antagonist (MRA) zum Einsatz. Relativ neu, aber mit überzeugenden Daten, ist die Substanzkombination Sacubitril / Valsartan. Das Erreichen der maximal verträglichen Dosis der einzelnen Medikamente ist essentiell für den Therapieerfolg. Diverse Zusatztherapien haben keinen erwiesenen Einfluss auf das Überleben, sind jedoch oft wesentlich für die Symptomfreiheit im Alltag. Wichtige Vertreter hierfür sind die Diuretika (Schleifendiuretika zeigen ein besseres Wirkungsprofil und sind den Thiaziden vorzuziehen), die Therapie eines Eisenmangels oder der Einsatz des Frequenzmodulators Ivabradin. Digoxin hat aktuell nur noch einen sehr begrenzten Stellenwert. Signifikante Rhythmusstörungen (vor allem Vorhofflimmern und ventrikuläre Arrhythmien) gehören zum klassischen Krankheitsverlauf. Neben Betablockern ist Amiodaron das Antiarrhythmikum der Wahl. Mit der frühen interventionellen Behandlung des Vorhofflimmerns mittels Pulmonalvenenablation ist gemäss neuster Daten eine Reduktion der Mortalität potentiell möglich. Neue Entwicklungen im Bereich der Antidiabetika sind bezüglich Therapieoptimierungen vielversprechend.
Ion mobility mass spectrometry workflows for characterizing bioactive isomer conformation, isomerization and drug–protein–liposome interaction
Authors: Ouyang Hui , Bo Tao , Zhang Zhengxiang , Guo Xinqiu , He Mingzhen , Li Junmao , Yang Shilin , Ma Xin , Feng Yulin
Published: August 2018

Ion mobility mass spectrometry enhances our ability to study conformational changes of bioactive isomers and their interactions with macromolecules.
Structures and phase transitions in molecular complexes containing tetrafluoroboric acid and tetramethylpyrazine
Authors: Rok M. , Szklarz P. , Bator G.
Published: August 2018

Crystals of tetrafluoroboric acid with tetramethylpyrazine, TMP + HBF4 + H2O (1 : 1 : 2, A), TMP + HBF4 (1 : 1, B) and TMP + HBF4 (1 : 2, C) were synthesized and characterized by physicochemical experimental methods.
Towards a coarse-grained model of the peptoid backbone: the case of N,N-dimethylacetamide
Authors: Du Pu , Rick Steven W. , Kumar Revati
Published: August 2018

Coarse-grained model of DMA, containing the basic motif of the peptoid backbone, based on short ranged many-body ranged interactions.
Synthesis of CoFeO mixed oxides via an alginate gelation process as efficient heterogeneous catalysts for lignin depolymerization in water
Authors: Hdidou L. , Khallouk K. , Solhy A. , Manoun B. , Oukarroum A. , Barakat A.
Published: August 2018

CoFeO mixed oxide, an efficient catalyst for lignin depolymerization in water to functional phenols.
Synthesis of new allyl palladium complexes bearing purine-based NHC ligands with antiproliferative and proapoptotic activities on human ovarian cancer cell lines
Authors: Scattolin Thomas , Caligiuri Isabella , Canovese Luciano , Demitri Nicola , Gambari Roberto , Lampronti Ilaria , Rizzolio Flavio , Santo Claudio , Visentin Fabiano
Published: August 2018

Some new palladium complexes show significantly higher cytotoxicity than cisplatin and are almost inactive on normal cells.
Enhanced indirect atomic H* reduction at a hybrid Pd/graphene cathode for electrochemical dechlorination under low negative potentials
Authors: Mao Ran , Lan Huachun , Yan Li , Zhao Xu , Liu Huijuan , Qu Jiuhui
Published: August 2018

Enhanced production and adsorption of atomic H* for efficient electrocatalytic dechlorination of TCAA with a Pd/rGO composite electrode.
Probiotics, mechanisms of action, and clinical perspectives for diarrhea management in children
Authors: do Carmo Monique Santos , Santos Camilla itapary dos , Araújo Mizael Calácio , Girón Jorge Alberto , Fernandes Elizabeth Soares , Monteiro-Neto Valério
Published: August 2018

Mechanisms of action of probiotics against enteric pathogens.
Reduction of the histamine content and immunoreactivity of parvalbumin inDecapterus maruadsiby a Maillard reaction combined with pressure treatment
Authors: Yang Huang , Min Juan , Han Xin-Yu , Li Xiao-Yan , Hu Jia-Wei , Liu Hong , Cao Min-Jie , Liu Guang-Ming
Published: August 2018

The aim of this study was to develop an effective method for decreasing the content of histamine and the immunoreactivity of parvalbumin inDecapterus maruadsi.
Cadmium associates with oxalate in calcium oxalate crystals and competes with calcium for translocation to stems in the cadmium bioindicator Gomphrena claussenii
Authors: Pongrac Paula , Serra Tânia S. , Castillo-Michel Hiram , Vogel-Mikuš Katarina , Arčon Iztok , Kelemen Mitja , Jenčič Boštjan , Kavčič Anja , Villafort Carvalho Mina T. , Aarts Mark G. M.
Published: August 2018

Cd binds to oxalate crystals, where it replaces Ca in the vacuoles of a bioindicator plant Gomphrena clausenii.
Synthesis, characterization and optimization of heterogeneous catalytic cyclohexene oxidation by tungstophospho(aqua)ruthenate via the fractional factorial design methodology
Authors: Zerrouki Mostapha , Boudjema Souheyla , Choukchou-Braham Abderrahim , Rekkab-Hammoumraoui Ilhem
Published: August 2018

Keggin-type tungstophospho(aqua)ruthenate (PRuW) was synthesized and supported on acid activated montmorillonite under mild conditions.
Porous CeO2 nanospheres for a room temperature triethylamine sensor under high humidity conditions
Authors: Zito Cecilia A. , Perfecto Tarcísio M. , Volanti Diogo P.
Published: August 2018

The porous CeO2 nanospheres showed an enhanced triethylamine sensing performance at 98% of relative humidity in terms of sensitivity, selectivity, repeatability, and response time.
Molecular iodine-catalysed oxidative CO–C(alkyl) bond cleavage of aryl/heteroaryl alkyl ketones: an efficient strategy to access fused polyheterocycles
Authors: Mani Geeta Sai , Rao Ayanampudi Venkata Subba , Tangella Yellaiah , Sunkari Satish , Sultana Faria , Namballa Hari Krishna , Shankaraiah Nagula , Kamal Ahmed
Published: August 2018

An efficient molecular iodine-catalysed one-pot strategy has been accomplished for the construction of various fused heterocycles under metal and oxidant free conditions.
Green synthesis of porous β-cyclodextrin polymers for rapid and efficient removal of organic pollutants and heavy metal ions from water
Authors: Yu Tingting , Xue Zhimin , Zhao Xinhui , Chen Wenjun , Mu Tiancheng
Published: August 2018

Rapid adsorption of organic pollutants and metal ions from water using porous β-cyclodextrin polymers.
Abnormal co-enzymatic behavior of a one-electron reduced bipyridinium salt with a carbamoyl group on the catalytic activity of CO2 reduction by formate dehydrogenase
Authors: Ikeyama S. , Amao Y.
Published: August 2018

A carbamoyl-modified bipyridinium salt has an enhancement and deactivation behaviour on the catalytic activity of CO2 reduction by formate dehydrogenase (FDH) from Candida boidinii.
Measuring the internal quantum yield of upconversion luminescence for ytterbium-sensitized upconversion phosphors using the ytterbium(iii) emission as an internal standard
Authors: May P. Stanley , Baride Aravind , Hossan Md Yeathad , Berry Mary
Published: August 2018

A new method is presented for estimating the internal quantum yield (IQY) of upconversion (UC) luminescence for Yb3+-sensitized ETU phosphors.
A chemiresistive sensor array from conductive polymer nanowires fabricated by nanoscale soft lithography
Authors: Jiang Yang , Tang Ning , Zhou Cheng , Han Ziyu , Qu Hemi , Duan Xuexin
Published: August 2018

A chemiresistive gas sensor array composed of well-ordered sub-100 nm wide conducting polymer nanowires was fabricated by using cost-effective nanoscale soft lithography.
MOF-templated synthesis of 3D Bi2O3 supracrystals with bcc packing
Authors: Guo Wei , Hassan Zeinab M. , Kübel Christian , Haldar Ritesh , Weidler Peter G. , Heissler Stefan , Peikert Katharina , Fröba Michael , Redel Engelbert , Wöll Christof
Published: August 2018

We describe a non-conventional, MOF-based approach with modified linkers to fabricate 3D Bi2O3 supracrystals.
High-quality and low-cost three-dimensional graphene from graphite flakes via carbocation-induced interlayer oxygen release
Authors: Zhang Jiajia , Zhao Xiaoli , Li Mengxiong , Lu Hongbin
Published: August 2018

In this study, we report a room-temperature and low-cost strategy for the construction of 3D graphene directly from graphite flakes.
Halide exchange and surface modification of metal halide perovskite nanocrystals with alkyltrichlorosilanes
Authors: Uddin Md Aslam , Calabro Rosemary L. , Kim Doo-Young , Graham Kenneth R.
Published: August 2018

Alkyltrichlorosilanes are demonstrated as efficient Cl-sources for rapid halide exchange with host CsPbBr3 nanocrystals. The resulting CsPbCl3 nanocrystals are encased in protective siloxane shells and are highly stable.
Plasmonic vesicles with tailored collective properties
Authors: Sun Hui , Du Jianzhong
Published: August 2018

Plasmonic vesicles from a thermo-responsive homopolymer vesicle show excellent stability under various conditions and tunable collective properties.
Polycycloacetals via polytransacetalization of diglycerol bisacetonide
Authors: Hufendiek Andrea , Lingier Sophie , Espeel Pieter , De Wildeman Stefaan , Du Prez Filip E.
Published: August 2018

Diglycerol bisacetonide sourced from renewable, abundant and inexpensive glycerol is introduced as a building block for polycycloacetal (co)polymers, which cover a range in thermal and mechanical properties and degradability profile.
Fabrication of theranostic amphiphilic conjugated bottlebrush copolymers with alternating heterografts for cell imaging and anticancer drug delivery
Authors: Liu Fangjun , Zhao Xuezhi , Zhang Xiaolong , Zhang Xianshuo , Peng Jinlei , Yang Huiru , Deng Kaicheng , Ma Liwei , Chang Cong , Wei Hua
Published: August 2018

We reported the first example of polyfluorene (PF)-backboned bottlebrush (bb) copolymers with alternating POEGMA/PCL hetero brushes for cancer theranostics.
Using a mechanistic framework to characterise chemistry students' reasoning in written explanations
Authors: Moreira Patricia , Marzabal Ainoa , Talanquer Vicente
Published: August 2018

The central goal of this research study was to characterise the different types of reasoning manifested by high school chemistry students when building initial written explanations of a natural phenomenon. In particular, our study participants were asked to explain why a mixture of water and alcohol works as an antifreeze. Data collected in the form of written explanations were analysed using a mechanistic reasoning framework based on the characterisation of system components (e.g., entities, properties, activities, organisation) and paying attention to the causal models invoked by the participants in their explanations. Our analysis revealed that students at the same educational level construct a wide range of explanations for the same phenomenon that are indicative of different reasoning modes going from descriptive to relational to simple causal to emerging mechanistic. Although the explanations generated by students in our sample were not very sophisticated in terms of the causal models on which they relied, some participants were capable of generating mechanistic explanations using particulate models of matter. The framework for analysis introduced in this contribution can be of use to teachers and researchers in the characterisation of student reasoning.
Transition metal-free direct dehydrogenative arylation of activated C(sp3)–H bonds: synthetic ambit and DFT reactivity predictions
Authors: Lovato Kaitlyn , Guo Lirong , Xu Qing-Long , Liu Fengting , Yousufuddin Muhammed , Ess Daniel H. , Kürti László , Gao Hongyin
Published: August 2018

A direct and general mono-arylation of activated C(sp3)–H bonds with nitroarenes under transition metal-free conditions has been developed.
Catalytic enantioselective radical coupling of activated ketones with N-aryl glycines
Authors: Liu Yang , Liu Xiangyuan , Li Jiangtao , Zhao Xiaowei , Qiao Baokun , Jiang Zhiyong
Published: August 2018

Asymmetric H-bonding catalysis as a viable strategy for enantioselective radical coupling of ketones is demonstrated.
Near infrared excitation and emission in rare earth MOFs via encapsulation of organic dyes
Authors: Liu Chong , Eliseeva Svetlana V. , Luo Tian-Yi , Muldoon Patrick F. , Petoud Stéphane , Rosi Nathaniel L.
Published: August 2018

Dye RE3+-MOF hybrid exhibits both NIR excitation and emission within the biological diagnostic window, highlighting its potential for biological imaging.
Tailoring water stability of cellulose nanopaper by surface functionalization
Authors: Operamolla Alessandra , Casalini Stefano , Console Dario , Capodieci Laura , Di Benedetto Francesca , Bianco Giuseppe Valerio , Babudri Francesco
Published: August 2018

Cellulose nanopaper (CNP) is dipped in lauroyl chloride solution. The hydrophobic nanopaper produced (C12-CNP) is characterized considering the morphology, composition, crystallinity and water uptake dynamics.
Microscopic details of a fluid/thin film triple line
Authors: Twohig Timothy , May Sylvio , Croll Andrew B.
Published: August 2018

A microscopic study of a slender but rigid polymer film deformed by a liquid/vapour contact line.
Formation of lipid vesiclesin situutilizing the thiol-Michael reaction
Authors: Konetski Danielle , Baranek Austin , Mavila Sudheendran , Zhang Xinpeng , Bowman Christopher N.
Published: August 2018

Synthetic liposome formation utilizing the thiol-Michael reaction enables control over liposome lamellarity and facile functionalization of the phospholipid products.
A cluster size distribution theory to study the thermodynamics and phase behavior of multi-bonding single site solutes in patchy colloidal mixtures
Authors: Bansal Artee , Asthagiri D. , Chapman Walter G.
Published: August 2018

A general cluster distribution theory for phase behavior of mixed patchy colloids with any geometry of multi-bonding association patch.
Continuum percolation-based tortuosity and thermal conductivity of soft superball systems: shape dependence from octahedra via spheres to cubes
Authors: Xu Wenxiang , Zhu Zhigang , Zhang Dongyang
Published: August 2018

Understanding the effect of particle shape on the percolation threshold, tortuosity and thermal conductivity of soft (geometrical overlapping) particle systems is very crucial for the design and optimization of such materials, including colloids, polymers, and porous and fracture media.
Multi-scale progressive failure mechanism and mechanical properties of nanofibrous polyurea aerogels
Authors: Wu Chenglin , Taghvaee Tahereh , Wei Congjie , Ghasemi Arman , Chen Genda , Leventis Nicholas , Gao Wei
Published: August 2018

The nonlinear mechanical properties, deformation and failure mechanisms of polyurea aerogels (PUAs) were investigated using a multi-scale approach that combines nanoindentation, analytical and computational modeling.
Ellipsometric study of the complex optical constants of a CsPbBr3 perovskite thin film
Authors: Zhao Minglin , Shi Yujun , Dai Jun , Lian Jie
Published: August 2018

Complex optical constants and interband transitions of a hybrid perovskite CsPbBr3 thin film measured by spectroscopic ellipsometry.
Phototoxicity of traditional chinese medicine (TCM)
Authors: Li Xiaoqi , An Rui , Liang Kun , Wang Xinhong , You Lisha
Published: August 2018

Phototoxicity can cause toxic responses such as edemas and lesions, and is one of the severe adverse effects that largely limit the use of these phototoxic drugs. Some traditional Chinese medicines (TCMs) and their constituents have been reported to be phototoxic. However, to date, their phototoxicity information is still very limited, and lacks systemic investigation. This article presents the phototoxicity potential of various types of TCMs and their active components in an effort to provide valuable information for drug research and discovery to mitigate phototoxicity concerns. Some potential mechanisms of action (MoAs) of phototoxicity are discussed. In addition, in vivo and in vitro phototoxicity assays are summarized this review.
Riding the kinematic waves in the Milky Way disk with Gaia
Authors: Ramos P. , Antoja T. , Figueras F.
Published: August 2018

Context. Gaia DR2 has delivered full-sky six-dimensional measurements for millions of stars, and the quest to understand the dynamics of our Galaxy has entered a new phase.

Aims. Our aim is to reveal and characterise the kinematic substructure of the different Galactic neighbourhoods, to form a picture of their spatial evolution that can be used to infer the Galactic potential, its evolution, and its components.

Methods. We take approximately 5 million stars in the Galactic disk from the Gaia DR2 catalogue and build the velocity distribution in different Galactic neighbourhoods distributed along 5 kpc in Galactic radius and azimuth. We decompose their distribution of stars in the VR–Vϕ plane with the wavelet transformation and asses the statistical significance of the structures found.

Results. We detect distinct kinematic substructures (arches and more rounded groups) that diminish their azimuthal velocity as a function of Galactic radius in a continuous way, connecting volumes up to 3 kpc apart in some cases. The average rate of decrease is ∼23 km s−1 kpc−1. In azimuth, the variations are much smaller. We also observe different behaviours: some approximately conserve their vertical angular momentum with radius (e.g. Hercules), while others seem to have nearly constant kinetic energy (e.g. Sirius). These two trends are consistent with the approximate predictions of resonances and phase mixing, respectively. Besides, the overall spatial evolution of Hercules is consistent with being related to the outer Lindblad resonance of the Galactic bar. In addition, we detect new kinematic structures that only appear at either inner or outer Galactic radius, different from the solar neighbourhood.

Conclusions. The strong and distinct variation observed for each kinematic substructure with position in the Galaxy, along with the characterisation of extrasolar moving groups, will allow to better model the dynamical processes affecting the velocity distributions.
The luminous host galaxy, faint supernova and rapid afterglow rebrightening of GRB 100418A
Authors: de Ugarte Postigo A. , Thöne C. C. , Bensch K. , van der Horst A. J. , Kann D. A. , Cano Z. , Izzo L. , Goldoni P. , Martín S. , Filgas R. , Schady P. , Gorosabel J. , Bikmaev I. , Bremer M. , Burenin R. , Castro-Tirado A. J. , Covino S. , Fynbo J. P. U. , Garcia-Appadoo D. , de Gregorio-Monsalvo I. , Jelínek M. , Khamitov I. , Kamble A. , Kouveliotou C. , Krühler T. , Leloudas G. , Melnikov S. , Nardini M. , Perley D. A. , Petitpas G. , Pooley G. , Rau A. , Rol E. , Sánchez-Ramírez R. , Starling R. L. C. , Tanvir N. R. , Wiersema K. , Wijers R. A. M. J. , Zafar T.
Published: August 2018

Context. Long gamma-ray bursts (GRBs) give us the chance to study both their extreme physics and the star-forming galaxies in which they form.

Aims. GRB 100418A, at a redshift of z = 0.6239, had a bright optical and radio afterglow, and a luminous star-forming host galaxy. This allowed us to study the radiation of the explosion as well as the interstellar medium of the host both in absorption and emission.

Methods. We collected photometric data from radio to X-ray wavelengths to study the evolution of the afterglow and the contribution of a possible supernova (SN) and three X-shooter spectra obtained during the first 60 h.

Results. The light curve shows a very fast optical rebrightening, with an amplitude of ∼3 magnitudes, starting 2.4 h after the GRB onset. This cannot be explained by a standard external shock model and requires other contributions, such as late central-engine activity. Two weeks after the burst we detect an excess in the light curve consistent with a SN with peak absolute magnitude MV = −18.5 mag, among the faintest GRB-SNe detected to date. The host galaxy shows two components in emission, with velocities differing by 130 km s−1, but otherwise having similar properties. While some absorption and emission components coincide, the absorbing gas spans much higher velocities, indicating the presence of gas beyond the star-forming regions. The host has a star formation rate of SFR = 12.2 M⊙ yr−1, a metallicity of 12 + log(O/H) = 8.55, and a mass of 1.6 × 109 M⊙.

Conclusions. GRB 100418A is a member of a class of afterglow light curves which show a steep rebrightening in the optical during the first day, which cannot be explained by traditional models. Its very faint associated SN shows that GRB-SNe can have a larger dispersion in luminosities than previously seen. Furthermore, we have obtained a complete view of the host of GRB 100418A owing to its spectrum, which contains a remarkable number of both emission and absorption lines.
NuSTAR reveals that the heavily obscured nucleus of NGC 2785 was the contaminant of IRAS 09104+4109 in the BeppoSAX/PDS hard X-rays
Authors: Vignali C. , Severgnini P. , Piconcelli E. , Lanzuisi G. , Gilli R. , Mignoli M. , Comastri A. , Ballo L. , Iwasawa K. , La Parola V.
Published: August 2018

Context. The search for heavily obscured active galactic nuclei has been revitalized in the last five years by NuSTAR, which has provided a good census and spectral characterization of a population of such objects, mostly at low redshift, thanks to its enhanced sensitivity above 10 keV compared to previous X-ray facilities, and its hard X-ray imaging capabilities.

Aims. We aim at demonstrating how NGC 2785, a local (z = 0.009) star-forming galaxy, is responsible, in virtue of its heavily obscured active nucleus, for significant contamination in the non-imaging BeppoSAX/PDS data of the relatively nearby (≈17′) quasar IRAS 09104+4109 (z = 0.44), which was originally mis-classified as Compton thick.

Methods. We analyzed ≈71 ks NuSTAR data of NGC 2785 using the MYTorus model and provided a physical description of the X-ray properties of the source for the first time.

Results. We found that NGC 2785 hosts a heavily obscured (NH ≈ 3 × 1024 cm−2) nucleus. The intrinsic X-ray luminosity of the source, once corrected for the measured obscuration (L2−10keV ≈ 1042 erg s−1), is consistent within a factor of a few with predictions based on the source mid-infrared flux using widely adopted correlations from the literature.

Conclusions. Based on NuSTAR data and previous indications from the Neil Gehrels Swift Observatory (BAT instrument), we confirm that NGC 2785, because of its hard X-ray emission and spectral shape, was responsible for at least one third of the 20–100 keV emission observed using the PDS instrument onboard BeppoSAX, originally completely associated with IRAS 09104+4109. Such emission led to the erroneous classification of this source as a Compton-thick quasar, while it is now recognized as Compton thin.
Law enforcement against trade in counterfeit goods using well-known marks (a study in traditional markets in Medan)
Authors: Aflah
Published: August 2018

The illegal use of well-known marks for counterfeit goods is qualified as a criminal act. The act may cause damages to the owner of a well-known mark. The protection of a registered mark and a well-known mark through Law Number 15 Year 2001 on Trade Marks should be able to address issues related to mark infringement. The number of cases of illegal use of well-known marks is high because, in a business, using a well-known mark is more profitable than using own mark. Other factor which influences trade in counterfeit goods using well-known marks is the lack of public legal awareness as consumers, producers and traders. An empirical research method was applied in the research, using primary and secondary data. Maximizing trade in local goods using registered marks is one of effective ways to minimize trade in counterfeit goods using well-known marks in traditional markets in Medan. There are two possible solutions to this problem. The first solution is socializing Law on Marks to local producers, consumers and traders. The second solution is implementing a supporting program to help local producers register their rights to a mark.
Rights to restitution for child victim of criminal act under government regulation number 43 year 2017
Authors: Zuliah Azmiati , Ablisar Madiasa
Published: August 2018

The criminal act against children is a gross violation of human rights. The criminal act committed by the offenderis intolerable because it can affect their survival as well as growth and development. Therefore, the victim deserves legal protection. Restitution is one of forms of protection and fulfillment of the rights of the child to compensate any damages. So far, child victim of criminal act suffers not only material loss (countable) but also immaterial loss (uncountable) such as shame, loss of self-esteem, depression and/or traumatic anxiety.It is the fact that so far the rights of child victims to restitution are very often violated. Therefore, the child victim and his or her family feel that they do not given justice. It is hoped Government Regulation Number 43 Year 2017 will be able to give legal certainty to the victim to ensure that he or she can enjoy his or her rights to restitution for any loss he or she suffers as stipulated in Law Number 35 Year 2014 on the Revision of Law Number 23 Year 2002 on Child Protection. This research uses theory of justice as grand theory, law enforcement as middle range theory and theory of victimology as applied theory.
The application of empty fruit bunch (EFB) fibers of oil palm for the development of light structure materials and products
Authors: Syam Bustami , Muttaqin Maraghi , Mawardi  , Rozi Fachrur , Martgomi  , Hutagalung James
Published: August 2018

We have been involved in developing the use of EFB fibers for several light structural products, such as speed bumps, parking stoppers, helmets, and horse shoes. This paper presents our current research work on parking bumper made of EFB fibers to be utilized for power generation. The products are designed and produced in full scale covering the whole width of vehicles passing over the bumpers. The ideas are how to reserve kinetic energy harvested from the vehicles to convert into electricity to be stored in a battery. To obtain a structural integrity-proof material, the speed bumps were subjected several tests, e.g. static and impact tests as well as live body test using the kinetic energy obtained from vehicles pass over the speed bumps. For this, a speed bump station parallel to street zebra-cross was prepared. It was obtained that A-5 concrete foam type is suitable for 3B class road. The structural response of speed bumps were checked using ANSYS 17.0.
The responsibility of the regional heads against the management of regional finances
Authors: Sintara Dani , Nasution Faisal Akbar
Published: August 2018

In administering governance, Regional Heads are given an authority to manage the local finances independently. This authority is regulated in Law Number 9 of 2015 and Government Regulation Number 3 of 2007. Accountability of Regional Heads is a form of a democratic government. In a democratic government, the government has limited power and is not justified to act arbitrarily against its citizens. In reality, the implementation of the accountability is often the result of a political compromise. Political compromises occur due to the behavior of the political elite and the weakness of the existing legislation. This weakness relates to the mechanism of the accountability against the management of regional finances which opens an opportunity between the Regional Heads and the Regional House of Representatives (DPRD) to conduct a negative relationship. The political compromises in the accountability of the Regional Heads have had a negative impact on the local governance. Whereas, the purpose of implementing a regional autonomy is to improve the quality of justice, democracy and prosperity. Therefore, before the DPRD rejects the accountability of the Regional Heads, it must first be tested in the Supreme Court.
On quest of environmental tax implementation in Indonesia
Authors: Irianto Edi Slamet , Rosdiana Haula , Tambunan Maria RUD
Published: August 2018

The number of research evaluating the implementation of environmental tax using regulatory cost perspective is still limited. Whereas, this type of research is quite crucial in formulating tax policy to find the balance between regulatory function, revenue productivity and its impact on maintaining conducive business climate. Therefore, this research is aimed to elaborate types of environmental taxes applied in Indonesia, to map the problems arised of their implementation and their impact on regulatory compliance cost. This research occupied postpositivism paradigm with mixed method approach. The data were gathered through qualitative and quantitative technique. The result shows that eventhough Indonesia has not implement explicity a new environmental tax, there are a lot of quasi-environmental tax scatterly levied by local government and provincial government due to their authority given by the decentralization besides the corporate social responsibility performed by the business entities. Unfortunately, the reallocation budget framework on the tax/charged levied from the quasi-environmental tax has not been clear. Thus, it is essential to establish a comprehensive environmental tax with an integrated roadmap considering and accomodating the former quasi-environmental tax into a one package environmental tax policy with clear concept of earmarking with efficient collection cost.
The potential of geographical indications and Its legal protection
Authors: Sitepu Faradila Yulistari
Published: August 2018

The legal protection of Geographical Indication (GI) is given to Indonesian typical products to prevent them from being registered as overseas brands, as previously happened in the case of Toraja Arabica coffee registered by a Japanese company and the Gayo coffee by a Dutch company. With the foreign trademark registration, the products harvested from the land of Indonesia can no longer be recognized as belonging to Indonesia because they can hardly be claimed to have come from Indonesia. Therefore, it is the foreign party that will enjoy the benefits of the famous Indonesian products. Geographical indication certainly requires a legal protection. This is important so that the natural rights owned by the original holder can be guaranteed and a sense of security can be realized. A product yielded from the nature and human creativity that has distinctive features, cannot be found elsewhere, and has a reputation that can increase the competitive power of the original region should get more attention from the government, especially the local government. The legal protection of Geographical Indication does not only provide economic benefits to the right holder, but also to the geographical environment of the product origin.
Tracing the causality between Livestock and poverty alleviation in the rural economy of Gilgit Baltistan-Pakistan
Authors: Hameed Gulnaz , Shaheen Shagufta , Saboor Abdul , Sadozai Khuram Nawaz
Published: August 2018

Livestock rearing and its production are deemed as a lucrative economic activity which provides livelihood and sustainable growth to rural population of Gilgit Baltistan . This sector not only delivers variety of food and non-food products but also contributes in income generation and subsequently diminishes the rural poverty. The fundamental aim of this research endeavor was to assess the poverty status and its determinants for livestock growers of the study area. The primary data was gleaned from 100 respondents through interview schedule following systematic sampling procedure. Uni-dimensional poverty estimates for sampled respondents employing Foster, Greer, and Thorbecke (FGT) poverty index are incorporated as dependent variable to model the binary probability expressions through Logit. Out of Explanatory variables used in model, benefit from the livestock, age, form size and gender of household head, showed a significant but negative relationship with poverty status whereas, household size and education of household head had a insignificant influence on poverty. This study recommends, that increase in farm size and youth’s participation in livestock farming can elevate the household income. The capacity building of the livestock farmers through trainings and more women contribution in livestock sector should be encouraged to reduce poverty in the area which can play a remarkable role in sustainable economic growth.
The concept of essential facilities in the efficiency of industrial natural resources
Authors: Kurnia  , Suryodhahono Bramantyo , Dewi R Ismala , Saragi Putri A
Published: August 2018

The concept of ‘essential facilities’ is known as a tool to request an access of a vital facility to an undertaking having a dominant position in the market. The concept of ‘essential facilities’ can also be regarded as a code of ethics in the utilization of vital facilities because it regulates the ethics of utilizing it. According to the concept of ‘essential facilities’, the utilization of a vital facility must be fair and equitable among all parties and none of the parties can dominate it. This doctrine is of course applicable to maintain fair competition within a market. However, by opening an access to a vital facility in natural resources industry, the essential facility doctrine will also be a supporting factor to achieve green industry concept in natural resouces industry. In this paper, SWOT analysis will be conducted to explore the strengths, weaknesses, opportunities, and threats to essential facilities in the efficiency of industrial natural resources with regard to green industry concept, in order to realize a sustainable industry where there is efficiency, effectiveness, and also able to maintain environmental sustainability.
Characterization of cellulase from E. coli BPPTCC-EGRK2
Authors: Haryanto Mas Gunawan , Setyahadi Siswa , Sahlan Muhammad , Yohda Masafumi , Fukutani Yosuke , Suryono Eko Agus , Gozan Misri
Published: August 2018

Cellulase enzymes are widely used in various industries such as detergent industry, bioethanol, animal feed, textile and paper. This research focused on characterization of cellulase produced from Eschericia coli BPPT-CC EgRK2, which is a recombinant that can produce protein enzymes endo- β-1,4-glucanase. Eschericia coli BPPT-CC EgRK2 was cultured in 1 litre liquid medium Luria Bertani. Because the bacteria is intracellular, sonication is needed for cell disruption to get the cellulase enzyme. The enzyme activity was then analyzed by CMC substrate at different concentration. The protein content analysis was carried out using Bradford method; the molecular weight analysis was done using SDS-PAGE; while the enzyme kinetics was plotted using Michaelis-Menten model. Our results showed the highest enzyme activity was 2.403 U/ml and the protein concentration was 5.352 mg/ml. The Michaelis-Menten constant (Km) and maximum velocity (Vmax) for CMC substrate hydrolysis were 0.07 μmol/ml and 2.49 μmol/ml/sec, respectively. The cellulase molecular weight was 58 kDa using SDS-PAGE with 7.5% stacking gel. The results indicated that Eschericia coli BPPT-CC EgRK2 is a promising renewable source for cellulase production for industrial application.
Development of stingless beekeeping projects in Malaysia
Authors: Ismail Mohd Mansor , Ismail Wan Iryani Wan
Published: August 2018

Malaysia is in need of new high income project to meet the targeted high income nation by 2020. One such potential project in agriculture is stingless beekeeping. The project could supplement the existing beekeeping projects from Apis spp. such as Apiscerana and Apis mellifera in terms of honey production and pollination services. The introduction of stingless beekeeping in 2004 by MARDI was expected to provide new alternative species that was free from diseases and required simple farm management practices where adopters can operate the project as a part time job. The remaining labour hours can be used to earn off farm income. The project alone could generate a monthly income of up to RM5000 for the adopters with available capital and land, and this will enhance additional income and dietary consumption of the stingless bee products. The project is hypothesized to provide positive relationship with income and nutritional quality. For those farmers with land, government assistance is needed in providing cheaper credit to purchase stingless bee colonies which are the major portion of initial investment. In summary, the project is expected to reduce rural and urban poverty and generate a new source of wealth to private investors in Malaysia.
Triangular concept of legal pluralism in the establishment of consumer protection law
Authors: Pasaribu Muldri Pudamo James , Sirait Ningrum Natasya
Published: August 2018

The new paradigm in legal pluralism is closely related to the phenomenon of globalization. Laws of various levels move into limitless territories. There is a strong contact and adoption between international, transnational, national and local laws. Such circumstances make it impossible for mapping that a certain law (international, national, local) is separated from other law systems. This is a normative legal research with a comparative law approach. Law as a global phenomenon has the common values throughout the world, namely ethical moral values, social values and formal values of the state. The same values apply to the consumer protection law in Indonesia. Law Number 8 of 1999 on Consumer Protection (UUPK) in Indonesia was developed on the basis of legal pluralism. The data were analyzed using a Triangular Concept of Legal Pluralism developed by Werner Menski. In conclusion, UUPK is a form of legal pluralism. It is enacted based on the community needs, legitimized by the state and based on values and ethics.
BOD Pressure in the sustainability of the Citarum River
Authors: Belinawati Resha Ayu Putri , Soesilo Tri Edhi Budhi , Herdiansyah Herdis , Aini Intan Nurul
Published: August 2018

As one of the 10 most polluted rivers in the world, Citarum river pollution has become the world’s spotlight. The pollution that occurred along the Citarum River in West Java has been the concern of the local government. Pollution not only comes from a plant and household, but also from industries. In this study the authors use descriptive quantitative method, where researchers will describe and compare the existing variables to see the possibilities that arise. Variable used is the number of industries that exist and how the impact against BOD. Biochemical Oxygen Demand (BOD) is a measuring instrument that is widely used to see the quality of oxygen levels in the water. In this paper shows that there is a possibility if BOD increases if the number of industries increases.
The implementation strategy of customary law aspect in protecting local environment
Authors: Lestarini Ratih , Tirtawening  , Harmain Riza , Wulandhary Succi , Utari Dyah
Published: August 2018

Environmental protection efforts have been made by the people, especially those still governed by customary law. Customary law serves to regulate society in all aspects of life, including the relationship between humans and between humans and the environment. The customary law also serves to regulate the use and the management of the environment efficiently for the purpose of preventing environmental damages and maintaining sustainability for the future. The communities which still have strong customary law will tend to preserve the environment and limit usages that cause damage to the environment. Cases of environmental damage that occurred today is very worrying. The formal law created is not sufficient to control it, so customary law is needed as an alternative to complementing the lack of formal law in order to effectively prevent the environmental damage. This research is aimed to determine the best way to protect the environment using customary aspect as the instrument. The method used in this paper is SWOT analysis that determines the strategies of the customary law in environment protection. The selection of the strategy was determined by the score and the weight of the pre-defined components. The results showed that the customary law, which has its own legal logic with aspects of local knowledge developed in the community for a long time as it relates to the values inherent culture and spiritualism, has a chance to be implemented in protecting environment. Customary law can be instrumental in preventing and protecting the environmental damage because the goal is to create harmony with nature.
A contrast among farmers’ ethnic groups: is this a social polarization tendency?
Authors: Taridal Siti Aida Adha , Wianti Nur Isiyana , Arsyad Muhammad , Ekaputri Arifiana Shima
Published: August 2018

The aim of the study was to capture the differences between Tolaki, Javanese, and Bugis ethnic in relation to their livelihoods in paddy upland farming activity. The study uses the post-positivism paradigm. In our research setting in Sulawesi drylands ecology, Tolaki local farmer, inhabit most areas of dry land, tend to be sub-subsistence and subsistence-oriented, their planting system is shifting cultivation, or the swidden farming, which was the legacy of their ancestors. Javanese tend to be subsistence and supra-subsistence oriented, while the Bugis farmer is expansive and supra-subsistence oriented. Another important message showed the symptoms of social polarization between the Tolaki and the Bugis as ethnic immigrants. The climax conditions will lead to social conflicts between Tolaki local farmer, Javanese, and Bugis migrants as a result of the emergence of social polarization.
Model availability of landfill as a conflict mediation process in Central Java
Authors: Pasha Yulia , Herdiansyah Herdis , Setyawati Lugina , Mutia Elok Faiqotul
Published: August 2018

Waste is still a problem in major cities in Indonesia. The high production of waste is not proportional to the availability of the landfill (TPA). The land use plans for waste landfill by local governments have conflict potential between government and community when such infrastructure facilities are not desired by the community. Environmental conflicts/disputes can be resolved through mediation mechanisms. This research uses linear regression modeling system to see the correlation between the amount of waste volume generated with the availability of landfill (TPA) in Central Java Province. The results showed the greater the number of residents the greater the volume of waste generated. In contrast the number of available landfill (TPA) is not affected by the volume of waste because the regression coefficient is only 0.0256.
De la nécessité d’une recherche de proportionnalité des solutions de gestion des déchets radioactifs à leur dangerosité
Authors: Hoorelbeke J.-M.
Published: August 2018

Une grande part des déchets radioactifs français disposent de filières d’élimination opérationnelles ou en cours de développement. Néanmoins, certains déchets interpellent aujourd’hui sur les modalités d’une gestion à long terme justement proportionnée à leur dangerosité, qu’il s’agisse des grands volumes de déchets de très faible activité qui seront produits par les démantèlements à venir ou de déchets aux caractéristiques intermédiaires, comme les déchets dits de faible activité à vie longue. La recherche de solutions de stockage s’inscrivant dans l’approche graduée recommandée par l’AIEA passe par une meilleure compréhension de la dangerosité des différents déchets et par une analyse des justes besoins en confinement et en isolement vis-à-vis de l’homme et de la biosphère. À ces besoins, pourront être associés des caractéristiques de barrières de long terme et des durées sur lesquelles les performances de ces barrières pourront être raisonnablement évaluées.
Motivational Interviewing in der Sport- und Bewegungstherapie – ein Ansatz zur Förderung der intrinsischen Motivation
Authors: Messner Thomas
Published: August 2018

Sport- und Bewegungsprogramme sind im Kästnerschen Sinne dann von Nutzen, wenn Sie umgesetzt und im wahrsten Sinne des Wortes getan werden. In dem Fall stellt sich die Frage, wie eine nachhaltige Verhaltensänderung unterstützt und begleitet werden kann und wie Menschen zu einem körperlich aktiven Lebensstil motiviert werden können. Mit dem Motivational Interviewing steht dem Bewegungs- und Sporttherapeuten ein evidentes und bewährtes Konzept zur Verfügung, mit dem intrinsische Motivation evoziert und Veränderungsprozesse unterstützt werden können. Der Ansatz verknüpft dabei die theoriegeleitete Betrachtung von Veränderungsprozessen mit einer auf Beziehung bauenden personenzentrierten Art des Umgangs mit dem Gegenüber.
Elevation in Circulating Soluble CD40 Ligand Concentrations in Type 2 Diabetic Retinopathy and Association with its Severity
Authors: Lamine Laila Ben , Turki Amira , Al-Khateeb Ghada , Sellami Nejla , Amor Hagger B. , Sarray Sameh , Jailani Mohamed , Ghorbel Mohamed , Mahjoub Touhami , Almawi Wassim Y.
Published: August 2018

Background To investigate the relationship between changes in circulating soluble CD40 ligand (sCD40L) levels and the presence and severity of type 2 diabetic retinopathy (DR).

Subjects and methods sCD40L plasma concentrations were measured in 205 type 2 diabetes (T2DM) patients without DR (DWR; n=50) and with DR (n=155), the latter subdivided into non-proliferative diabetic retinopathy [NPDR; n=98 (63.2%)], or proliferative retinopathy [PDR; n=57 (36.8%)] patients.

Results Receiver operating characteristic analysis provided good discriminatory power for sCD40L as predictor of DR presence, with high sensitivity and specificity. Categorizing DWR and DR patients into sCD40L quartiles, based on sCD40L concentrations in T2DM without DR, demonstrated statistically significant gradual increase in DR risk with increasing sCD40L levels. sCD40L levels were significantly higher in DR compared to DWR patients. Plasma sCD40L levels differed significantly according to DR severity, and correlated with diabetes duration, dyslipedimea, nephropathy, and presence of DR, but not with gender, age, SBP, DBP, FPG, HbA1c, T2DM medications. Linear regression analysis confirmed the association of increased sCD40L levels with DR, independent of others parameters; mean plasma sCD40L levels differing significantly according to DR severity.

Conclusion Plasma sCD40L levels were positively associated with DR. The significant finding here is that sCD40L levels can be predictors of DR severity.
Vom Statisten zum Protagonisten
Authors: Diana Gallmeier HP
Published: August 2018

Das Gefühl der Hilflosigkeit zählt zu den wichtigsten Ursachen für Entwicklungshindernisse sowie für soziale und psychische Probleme bei Kindern und Jugendlichen. Die jedem innewohnende natürliche Selbstwirksamkeit und Lösungskompetenz lässt sich therapeutisch gut ansprechen und liefert den Schlüssel zur Entspannung. Im Fall von Maximilian konnten schulische Ängste und Blockaden durch Visualisierung, Ankerübungen und das Freisetzen seiner Kreativität in Motivation überführt werden.