bluuebunny/crossref_metadata_2025 huggingface dataset:
Learners’ Perceptions of Pre-Service Teachers’ Classroom Management Practices
Authors: Nkhata Leonard , Banda Asiana , Simpande Alex , Jumbe Jack , Zulu Alfred , Musonda Allan
Published: September 2023

Studies conducted on learners rarely focus their investigations on learner perceptions of pre-service teachers’ classroom management practices. In response to the changing school environments, this study investigated learners’ perceptions of pre-service teachers’ classroom management practices. A survey design was adopted in which 550 grade 11 secondary school learners from eleven secondary schools in the Copperbelt Province in Zambia formed the sample. A Likert scale questionnaire was used to collect data which was analysed using SPSS and also through an iterative process. The study revealed that learners positively perceived pre-service teachers’ classroom management practices. This is indicated by pre-service teachers’ interest in learners’ welfare, possessing good personal qualities, ability to handle learners’ disruptive behaviours, ability to teach effectively, and ability to assess learners effectively. Using an independent samples t-test, it was concluded that there were no statistically significant gender differences in learners’ perceptions of pre-service teachers’ classroom management. Regardless of which institution pre-service teachers came from, learners had a positive impression of pre-service teachers in terms of learner discipline (60%), assessment of learners (66.3%), learner and pre-service-teacher relationship (64.7%), pre-service teachers’ ability to teach (54%), interest in learner welfare (58.5%), pre-service teachers’ personal characteristics (82.6%) and acceptance of pre-service teacher (46.9%).
Social Justice Leadership in the Refugees’ Education: Insights of Teachers in Turkish Secondary Schools
Authors: Akkaya Arzu , Tabancalı Erkan
Published: September 2023

The current case study examines secondary school principals’ social justice leadership (SJL) based on teachers’ perceptions. In the study, a qualitative research approach with a phenomenological design was used to explore the teachers’ perceptions regarding their principals’ SJL at Turkish secondary schools. The data were reached through semi-structured interviews. 11 participant teachers were determined as participants of the study with the maximum sampling method. The collected data were analyzed with content analysis, and three themes were reached: limited social justice, inclusive perspectives, and holistic leaders. Based on the results, teachers think that principals have a limited SJL and inclusion enactment. The participant teachers think that SJL should have a holistic perspective, including parents and teachers while ensuring social justice at school.
Cultivating Leadership Identity: Exploring the Motivations and Experiences of Aspiring School Leaders
Authors: Kudlats Jamie , La-Serna Jillian
Published: September 2023

We know that school principals are critical to school success and must have the appropriate knowledge, skills, and dispositions to lead effectively. However, research shows that identifying these potentially effective leaders is difficult. Furthermore, little is known about the motivations and experiences of aspiring school leaders. This study, conducted at a university in the Southeast United States, aims to understand better the lived experiences and motivations of aspiring public and private school leaders enrolled in graduate principal preparatory programs. Through phenomenological document data analysis of 38 written narratives from 19 participants, the authors revealed several common experiences contributing to participants’ leadership identity development: early life leadership experiences, exposure to models of leadership, and leadership opportunities in their professional lives. Findings also support existing literature on the altruistic motivations of school leaders. Finally, the authors discuss implications centered primarily on growing the principal pipeline, suggesting a focus on youth/student leadership opportunities and teacher/staff leadership experiences.
Questioning development from Black feminisms in Ecuador and moving towards a Black feminist political ecology in the Americas
Authors: Zaragocin Sofia , Bone Juanita Francis , Boudewijn Inge , Jenkins Katy
Published: September 2023

This article critically explores tensions concerning development from contemporary feminist thought and praxis in Latin America. In Ecuador, development is seen as an outdated and irrelevant theoretical framework from a variety of feminist perspectives, including feminist political ecology and decolonial feminisms. Nevertheless, development discourse and practices persist and are central to public policy with a gender focus throughout the country. This results in tensions between governmental and autonomous feminist perspectives that are present in local spaces, such as the province of Esmeraldas in Northern Ecuador. Drawing on research conducted with Afro-Ecuadorian peer researchers, including interviews, oral histories and social-cartography methods, this article will demonstrate how Afro-Ecuadorian women are challenging dominant ideas and practices of development from the emerging ideas of Black feminism in Ecuador and moving towards a Black feminist political ecology in the Americas.
The sequencing of the key genes and end products in the TLR4 signaling pathway from the kidney of Rana dybowskii exposed to Aeromonas hydrophila
Authors: Wang Boju , Shao Jie , Qu Lili , Xu Qing , Zheng Dong
Published: September 2023

Infectious diseases caused by Aeromonas hydrophila (AH) have reduced the populations of Rana dybowskii). However, little is known about the immune response of R. dybowskii against AH infections. The toll-like receptor (TLR) signaling pathway has been identified as a critical component in innate immunity, responsible for identifying pathogen-associated molecular patterns in pathogens. Our study used the next-generation sequencing technique and single-molecule long-read sequencing to determine the structures of transcript isoforms and functions of genes in the kidneys of R. dybowskii, as well as identify and validate the related genes in the TLR4 signaling pathway. In total, 628,774 reads of inserts were identified, including 300,053 full-length non-chimeric reads and 233,592 non-full-length reads. Among the transcriptome sequences, 124 genes were identified as homologs of known genes in the TLR4 pathway especially inflammatory cytokines and receptors. Our findings shed light on the structures and functions of R. dybowskii genes exposed to AH and confirm the presence of both MyD88-dependent and independent pathways in R. dybowskii. Our work reveals how various functional proteins in amphibians at the initial stage of immune response are activated and complete their corresponding functions in a short time.
Code-Switching in reichsbürgerlichen Texten. Eine Fallstudie am Beispiel der Reichsbürger-Organisation S.H.A.E.F.
Authors: Schuppener Georg
Published: September 2023

Der Beitrag untersucht, welche Rolle Code-Switching in Texten von Reichsbürgern spielt. Untersuchungsgrundlage dafür ist ein Korpus von 249 Texten, die aus der Internet-Domäne s-h-a-e-f.de entnommen sind. Zunächst wird dieses Korpus näher beschrieben, danach wird quantitativ ausgewertet, wie viele dieser Texte Code-Switching aufweisen. Dabei zeigt sich, dass in mehr als einem Drittel der Texte Code-Switching nachweisbar ist. Bei der näheren Betrachtung der betreffenden Texte wird deutlich, dass ein Teil der Fälle von Code-Switching auf Probleme bei der (automatischen) Übersetzung US-amerikanischer Textvorlagen zurückzuführen ist. Diese Texte wurden von der weiteren Untersuchung ausgeschlossen. Bei den verbleibenden Texten ließ sich in vielen Fällen feststellen, dass Code-Switching an exponierten Positionen auftritt. Dies lässt darauf schließen, dass Code-Switching hier für die Erregung von Aufmerksamkeit, aber auch für die Betonung von Authentizität und Internationalität eingesetzt wird. Weitere Belege für die Nutzung von Code-Switching lassen sich auf die üblichen Funktionen von Code-Switching zurückführen, wie z.B. Ausfüllen eines Bezeichnungsbedarfes, Erklärung, Glaubhaftmachung der eigenen Aussagen usw. Darüber hinaus kann nachgewiesen werden, dass Code-Switching auch gezielt eingesetzt wird, um die ideologischen Botschaften der Reichsbürger (insbesondere die Ablehnung der staatlichen Existenz der Bundesrepublik Deutschland) zu unterstützen.
Improved modeling of Janus membrane considering the influence of hydrophilic layer characteristics
Authors: Sayed Noha M. , Noby H. , Thu Kyaw , El-Shazly A. H.
Published: September 2023

Some of the previous investigations neglect the mass transfer contribution of the hydrophilic layer for modeling the Janus membrane that is used for direct contact membrane distillation (DCMD). This work studies the impact of adding such resistance on the performance of the DCMD, especially on the temperature polarization coefficient (TPC), thermal efficiency, and permeate flux. The commercial software Ansys 2020 was used to describe the transport behavior through the Janus membrane. The bulk-flow model was employed to evaluate the permeate flow through the hydrophilic layer for the first time. Simulation results were compared with the experimental results from the literature for validating the model, and a satisfactory agreement was found. Results demonstrated that the permeate flux increased by about 61.3 % with changing the porosity of the hydrophilic layer from 0.5 to 0.9 for the membrane with the lowest hydrophilic layer thickness. Moreover, the thermal conductivities of both layers contribute significantly to the DCMD’s overall performance enhancement. Vapour flux might be enhanced by increasing the hydrophilic layer’s thermal conductivity while decreasing the hydrophobic layer’s thermal conductivity. Finally, the DCMD thermal efficiency was investigated, for the first time, in terms of both layer characteristics.
A pan-cancer analysis of STAT3 expression and genetic alterations in human tumors
Authors: Tan Junyin , Feng Ronghao
Published: September 2023

Combined cancer immunotherapy and targeted therapy have proven to be effective against various cancers and therefore have recently become the focus of cancer research. Signal transducer and activator of transcription 3 (STAT3) is a member of the STAT protein family of transcription factors. Several studies have shown that STAT3 can affect the prognosis of cancer patients by regulating immune microenvironment (IME). Therefore, STAT3 may have high research value for the development of combined immunotherapy/targeted therapy approaches for the treatment of cancer patients. We found differences in STAT3 expression between tumor and normal tissues. Kaplan−Meier survival and Cox regression analyses showed that high expression of STAT3 is associated with poor prognosis in low-grade glioma (LGG) patients. The results of the analysis of the area under the curve of the receiver operating characteristic curve further suggested that the expression of STAT3 is an effective way to evaluate the prognosis of patients with glioma. The results of the IME analysis revealed that the immune and matrix scores of LGGs were positively correlated with the expression of STAT3 (P < 0.05). The results of immune cell infiltration analysis showed that STAT3 was positively correlated with resting dendritic cells, eosinophils, neutrophils, M0 macrophages, M1 macrophages, CD4 memory resting T cells, and CD8 T cells in LGG patients, but negatively correlated with activated mast cells and M2 macrophages (P < 0.05). Our gene set enrichment analysis identified 384 enriched pathways. According to the enrichment scores, the top ten most significantly upregulated pathways were related to immune response. The top ten most significantly downregulated pathways were related to cell signal transduction and the regulation of cell survival, proliferation, and metabolism. Genetic alteration analysis showed that missense mutations in STAT3 account for the majority of mutations, and STAT3 mutations mostly occur in the Src homology domain. In conclusion overexpression of STAT3 can promote the development and growth of tumors by regulating IME, which is significantly related to the poor prognosis of cancer patients. Therefore, targeted inhibition of STAT3 expression may have high research value for the development of combined immunotherapy/targeted therapy approaches for the treatment of cancer patients.
Mechanical analysis of composite plates adhesively joined with different single-lap techniques under bending loading
Authors: Sülü İsmail Yasin
Published: September 2023

In this study, composite plates adhesively joined using single-lap joint without intermediated material (SLJ) and intermediated material (IM-SLJ) subject to bending loading were investigated via finite element analysis. DP 410 type adhesive was used. Composite parts and intermediate material were preferred as T700 carbon/epoxy. Numerical analyses were carried out using ANSYS 14.5 software package, in which the finite element method was taken into account. Failure situations for adhesive and composites were examined by the von-Mises failure criteria and the Tsai-wu failure criteria, respectively. Firstly, the failure loads for each parameter situation were determined. The equivalent stresses of the critical stress lines on adhesive layers were examined and critical stresses line were determined for length and width of adhesive layers. Shear, normal, and von-Mises stresses were investigated at obtained failure load for each parameter of SLJ and IM-SLJ. The von-Mises on the critical stress lines were compared for different overlap width and length of SLJ and IM-SLJ. The effects of joint techniques, orientation angles, and overlap dimensional were investigated on adhesive layer, and joint techniques were compared about advantages. A different study from the literature was carried out to compare the mechanical behavior of SLJ and IM-SLJ joining techniques.
Optimal interatomic potentials using modified method of least squares: Optimal form of interatomic potentials
Authors: Surulere Samuel , Shatalov Michael , Olayiwola Elizabeth
Published: September 2023

The problem of optimization of interatomic potentials is formulated and solved by means of generalization of the Morse, Kaxiras–Pandey, and Rydberg potentials. The interatomic potentials are treated as solutions of some second-order ordinary differential equations which will be classified and analyzed. The most appropriate analytic form of the understudied potentials will be proposed based on a one-dimensional search for the parameter,

γ

\gamma

, which is the power of the interatomic distance,

r

r

. The optimal analytic form will also be proposed for metals such as gold, copper, aluminium, titanium, and the silver–copper alloy. The method of least squares will be used to estimate the potential parameters. Phenomenological potentials such as the classical Rydberg, classical Morse, generalized Morse, Kaxiras–Pandey, and classical Lennard–Jones will be studied, and new potentials based on the combination of some of the aforementioned potentials will also be proposed. Metrics such as the goal function values, will be used to identify which optimal value of the parameter,

γ

\gamma

, is most appropriate to introduce into the preferred interatomic potential for interaction between atoms.
Dynamic Mechanical Analysis Test for Evaluating Loose Sands on a Wide Strain Range—Application to the InSight Mission on Mars
Authors: Chaparro López María Juliana , Castillo-Betancourt Juan-Pablo , Cabrera Miguel , Caicedo Bernardo , Delage Pierre , Lognonné Philippe , Banerdt Bruce
Published: September 2023

The dynamic properties of loose sands under low stresses are an unexplored topic in soil dynamics because these soil conditions are uncommon in most geotechnical structures on Earth. However, low densities and low-stress conditions prevail on other planets, like, for instance, the surface of Mars, for which particular attention is presently given through the InSight NASA mission. This work presents a new procedure for measuring the dynamic properties of loose sand under low stress by using the dynamical mechanical analysis (DMA) tester, a technique commonly used in asphalt engineering but not in geotechnical engineering. Compared to traditional geotechnical methods (resonant column and cyclic triaxial tests), DMA investigates a broader range of strains using a single apparatus. In this work, we assess the dynamical properties of loose fine sand Dr ≈ 0.2, considered a possible Mars regolith analog, by varying the input strain from γ = 10−6 to γ = 10−2 while applying confining pressures from σ3 = 3 kPa to σ3 = 30 kPa. The results validate the proposed procedure, showing an increment of the shear modulus as the confining pressure increases. Furthermore, they highlight DMA’s advantages for studying the dynamic properties of granular soils under low stress and strain.
Estatus taxonómico de Talides basistrigata Eaton, 1932 (Lepidoptera, Hesperiidae) y su reincorporación basados en una evaluación integrativa
Authors: Lazo-Rivera Ana , Condori-Mamani Moisés , Arivilca-Garcia Melany , Aguilar-Guevara Yohana , Farfán Jackie , Cerdeña José , Huanca-Mamani Wilson , Lamas Gerardo
Published: September 2023

Talides basistrigata Eaton, 1932, originalmente descrita de Perú, posteriormente fue transferida por Evans (1955) al género Hylephila Billberg, 1820, y considerada como una subespecie de H. phyleus (Drury, 1773), argumentando que basistrigata ocurre en ambientes más secos que los que habita phyleus. Actualmente se mantiene el rango taxonómico propuesto por Evans. El objetivo del presente trabajo es restituir el estatus taxonómico de especie válida para basistrigata con base en un análisis integrativo considerando aspectos morfológicos, ecológicos y genéticos. Se examinó las estructuras genitálicas en ejemplares de basistrigata y phyleus, se obtuvo secuencias del gen mitocondrial COI para ambas especies y se recopiló datos en campo para conocer su comportamiento de oviposición en los alrededores de Arequipa, suroeste de Perú. Como resultado del examen morfológico se halló diferencias notorias entre las estructuras genitálicas de ambas especies, principalmente en los procesos caudales de las valvas, la disposición de las pectinas y la forma del uncus en los machos. Con relación al análisis genético, se halló una distancia genética mayor a 3% entre ambas especies, apoyando así el estatus taxonómico de especie para basistrigata. Adicionalmente, desde una perspectiva ecológica, se registró que ambas especies utilizan distintos mecanismos de oviposición y diferentes plantas hospederas, exhibiendo además simpatría espacial y sincronía temporal en la vertiente occidental de los Andes en Perú. Se redescribe el macho y hembra adultos de basistrigata y se designa su lectotipo.
Pachyoliva columellaris G.B. Sowerby I, 1825 (Olividae, Caenogastropoda) in Peru: tidal migrations and population density
Authors: Peters Winfried
Published: September 2023

The gastropod Pachyoliva columellaris (formerly Olivella columellaris) is particularly common on many sandy beaches in North Peru. In the studied region north of Paita, Piura province, the species reaches densities of over 80000 individuals per beach meter. The snails perform tidal migrations throughout the lunar cycle although tidal amplitudes differ four-fold between neap and spring tide. Not all animals complete their tidal migrations, and significant numbers remain above the water line at low tide. Throughout the tidal cycle, the proportion of small individuals is increased near the water line whereas large animals dominate in lower beach zones. I conclude that the sandy beaches north of Paita are well-suited for further studies of P. columellaris and the mechanisms underlying tidal migrations in invertebrates.
Contribution to the knowledge of cladocerans fauna (Crustacea, Branchiopoda) from La Española lagoon, Colombia
Authors: Fuentes-Reinés Juan M. , Vásquez-Ramos Jesús M. , Elmoor-Loureiro Lourdes M.A. , Sousa Francisco Diogo R. , Eslava-Eljaiek Pedro
Published: September 2023

Thirty-five cladocerans species are recorded from La Española lagoon in the Orinoquia region of Colombia; all are new records for Meta Department and 10 for Colombia. With the addition of these new reports, the total number of cladocerans for Colombia and the Meta department is increased by 124 and 38 species, respectively. The cladoceran fauna from the surveyed area is represented mainly by widespread species, commonly found in the Neotropical regions, but local morphological data are scarce in the regional literature. Brief diagnostic description of 18 species of cladoceran fauna recorded of the Meta department-Colombia are provided together with illustrations of taxonomically significant appendages, morphological remarks, notes on the variability of some species, and their distribution.
Caracterización de consorcios microbianos lixiviantes de sulfuro de cobre aislados de drenajes ácidos de minas altoandinas
Authors: Rodriguez-Venturo Sofia , Herrera-Quiñonez Josemaría , Reyes-Moreno César Bryan , Antezana-Mejía Jaime , Calderón-Alzamora Julio , Ramírez Pablo
Published: September 2023

La biolixiviación, usando consorcios microbianos, es considera una alternativa ecoeficiente y de bajo costo para la recuperación de metales a partir de minerales de baja ley. En este estudio, se realizó la caracterización fisiológica y molecular de consorcios microbianos psicrotolerantes lixiviantes (CMPL), aislados de drenajes ácidos de minas de cuatro localidades mineras de las provincias de Pasco y Huarochirí, Perú, ubicados sobre los 4200 m de altitud. Se aislaron seis consorcios adaptados a medio 9K con ion ferroso y medio basal 9K con CuS al 0.5% p/v a 15 °C. Se evidenció la liberación de cobre en todos los consorcios. El CMPL con mejor crecimiento, presentó una recuperación de cobre de 12.47% en 30 días de evaluación. Los análisis de la secuenciación del gen ARNr 16S de la comunidad bacteriana, mostraron que los CMPL están dominados por el género Acidithiobacillus, seguido de Acidiphilium. En conclusión, se obtuvieron consorcios que pueden ser aplicados en biolixiviación de cobre en la minería altoandina.
Yousiyue induced pulmonary embolism: a case report
Authors: Zhu Xiangjun , Chen Yin , Ma Danhua , Li Ming
Published: September 2023

We evaluate a case report of Yousiyue induced pulmonary embolism in order to provide reference for safety use of oral contraceptives.
CAR T cells and dendritic cells: vaccinomics perspectives
Authors: Anurogo Dito
Published: September 2023

Immunotherapy has revolutionized cancer treatment with Chimeric Antigen Receptor (CAR) T cells and dendritic cell-based vaccines showing remarkable efficacy in certain malignancies. This review provides an integrative overview of recent advances and future directions in vaccinomics. A critical aspect of improving efficacy is the integration of CAR T cells and dendritic cell-based therapies to leverage synergistic effects. Personalization of cancer treatment, facilitated by strategies such as HLA typing and antigen selection, is essential for targeting specific tumor antigens and evading immune resistance. The tumor microenvironment plays a crucial role in modulating immune responses and can be targeted to enhance therapy efficacy. Novel adjuvants and immune modulators, such as Toll-like receptor agonists and checkpoint inhibitors, can further improve efficacy and safety. Predictive biomarkers and patient stratification strategies are essential for optimizing candidate selection. Future research should focus on optimizing CAR T cell and dendritic cell-based therapies, developing novel combinational strategies, and advancing gene editing and manufacturing techniques. Expansion to non-cancerous diseases could greatly broaden the impact on public health. Addressing challenges and limitations associated with these therapies can unlock their full potential and revolutionize the treatment of various malignancies and other medical conditions.
Artificial intelligence and rehabilitation: what’s new and promising
Authors: Marks Ray
Published: September 2023

The development of artificially intelligent technological machine systems that can integrate large volumes of data, and also ‘learn’ to recognize notable patterns, are currently being widely discussed and employed in various health and other realms. In this regard, what promise do these systems hold for ameliorating the late life chronic disease burden of increasing numbers of adults globally that may stem from one or multiple chronic longstanding health conditions. To explore this issue, a broad exploration of rehabilitation associated artificial intelligence implications was conducted using leading data bases. Results show that there are some active advances in both artificial intelligence and machine learning realms, but not in the context of desirable robust observations in all cases. Much future work is indicated though and is strongly recommended.
Incidence and risk factors associated with the occurrence of encephalic vascular accident in the pregnancy-puerperal cycle: an integrative review
Authors: de Menezes Teles Pedro Lucas Santos , Serafim Joan Lins , Katharinne Souza Lima Amanda , Santos Coelho Jéssica dos , Moreira Lun Valda Lúcia , da Silva Carolina Maria , Machado Galvão Pauliana Valéria , https://orcid.org/0000-0001-6649-577X George Alessandro
Published: September 2023

Background: The encephalic vascular accident (EVA), also called stroke, is a complication that leads to high morbidity during the gestational period. The incidence of encephalic stroke is three times higher in pregnant women compared to non-pregnant women, with an increase in rates in recent years. Considering the impacts of this comorbidity on the maternal-fetal health, this review aims to compile data regarding the incidence and risk factors related to the occurrence of EVA in the pregnancy-puerperal cycle, in order to facilitate the identification of risk factors and the prevention of an unfavorable outcome. Methodology: This is an integrative review of the literature. The research was conducted using the databases from the Medical Literature and Retrivial System onLine (MEDLINE), Scientific Electronic Library Online (SciELO) and Latin American and Caribbean Literature on Health Sciences (LILACS). The information was systematized based on the guiding question: “What is the incidence and risk factors related to the occurrence of encephalic vascular accident in the pregnancy-puerperal period?”. The descriptors used were: “Pregnant Women” AND “Stroke”. Original and complete articles, with free access, in English or Portuguese language, published in the last five years and with a detailed description on the subject were included in this review. Results and discussion: The incidence of pregnancy hospitalizations due to EVA ranged from 7.3 to 42.8 per 100,000 pregnant in the studies evaluated. Related to risk factors, a relationship was found with physiological changes during pregnancy, especially the state of hypercoagulability due to the increase in levels of prothrombotic factors. Additionally, hypertensive disorders during the pregnancy, such as eclampsia and pre-eclampsia, and traditional cardiovascular risk factors such as smoking, sedentary lifestyle, dyslipidemia and advanced age, were also considered risk factors for stroke. Conclusion: Despite being an uncommon complication during the pregnancy-puerperal cycle, stroke has a severe impact in women and fetus health, this condition is being related to physiological alterations inherent to pregnancy, pathological alterations and modifiable risk factors.
Brief essay on neuroregenerative medicine: approaching a new era through stem cell therapy techniques
Authors: Martínez-Canca Juan F , Martínez-Soler Pablo , Nasim Boshor Mohamed
Published: September 2023

Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and spinal cord injuries amongst others pose significant challenges to modern Medicine. Traditional treatments often focus on symptom management rather than targeting the root causes of these conditions. However, the advent of Neuroregenerative Medicine represents a cutting-edge field that aims at restoring the structure and function of the nervous system, particularly in cases of injury or degenerative diseases. Stem Cell therapy techniques have excitingly emerged as a promising avenue in this domain, offering the potential to repair damaged neural tissue, promote its regeneration, and restore lost function. This brief essay explores the principles behind Neuroregenerative Medicine and highlights the applications, challenges, and prospects of Stem Cell therapy in treating neurodegenerative disorders.
Visual allesthesia: looking through a negative prism? A review
Authors: Drapkin Allan J
Published: September 2023

Visual Allesthesia is a rare misperception consisting of the visualization of an object, briefly exposed to view, whose resulting image is seen in one hemifield of vision while a duplicated image is viewed simultaneously in the opposite visual hemifield. It is the result of diverse medical or surgical conditions that cause disruption of the ventral visual stream. Surgical procedures that cause damage of that area should be avoided.
Alzheimer’s disease: is there a way out of the deaf corner?
Authors: OD Rudkovska
Published: September 2023

Alzheimer's disease and primary open-angle glaucoma have common links of pathogenesis, so they may have the same trigger - an excessively narrowed pupil, manifested by activation of the parasympathetic nervous system. It is advisable to start the treatment of Alzheimer's disease with medical or surgical dilation of the pupil. This approach can be useful in the treatment of migraine, epilepsy, schizophrenia, post-traumatic stress disorder and other diseases that begin with excessive activation of the parasympathetic nervous system
Echinacea purpurea, a pathway to increased immunity
Authors: Ciaccio Vendola Maria Cecilia
Published: September 2023

This work aims to return scientific interest to the valuable biochemical components found in Phytotherapy in times of exponential growth of viral propagation in the world. The topic addressed will be specifically the Echinacea Purpúrea plant, a member of the Compositae or Asteraceae family, which has been researched all over the world , may open up new possibilities for the treatment of oral and systemic diseases , using its own biochemistry as a stimulating factor to increase immunity. Recent studies in humans have shown actions of interest in the immune response with its use, both in aerial part and roots.
Technology of preparation of defective cocoons for reeling
Authors: Adkhamovich Akhmedov Jakhongir , Akmal Jumaboev , Sharipov Jurabek Sharipov , Quziboy Sobirov , Izzatbek Atabaev
Published: September 2023

In this article, one of the ways to effectively use non-smooth defective cocoons that cannot be used in reeling is covered. An analysis of the development of the silk industry and the scientific work currently being carried out in this direction is presented. Water and air permeability of defective cocoons produced during cocoon sorting, evaporation regimes, influence of solution concentration on cocooning was studied by single cocooning. It is based on the fact that the amount of raw silk can be increased by introducing the spinning of defective cocoons. In order to achieve the set goal, separate cooking and water filling regimes of defective cocoons depending on the type of defect were determined based on experiments. A new processing method is recommended for cooking defective cocoons. Recommended technological parameters and modes for workshops are presented in the tables. Defective cocoons with a new concentration based on the type of defect recommended.
LATEST RESTAURANT BUSINESS IN THE HOSPITALITY INDUSTRY
Authors:   National University of Food Technology, Kyiv, Ukraine, Shydlovska Olena , Ishchenko Tetiana ,   National University of Food Technology, Kyiv, Ukraine, Dulka Оlha ,   National University of Food Technology, Kyiv, Ukraine
Published: September 2023

The aim of the article is to substantiate the introduction of the latest restaurant business for hospitality enterprises by analyzing the main directions of molecular technologies. Research methodology. The article is based on scientific works of foreign and domestic scientists in the field of hotel and restaurant business. The general scientific methods of analysis for processing, presentation and generalization of the received data are used in the work. Research results. The introduction of innovations in the market of hotel services indicates the need for the harmonious development of hospitality facilities, which in the long run will provide the possibility of sustainable income for the establishments of the hospitality industry. The latest restaurant technologies enable hotel enterprises not only to occupy leading positions in their market segments, but also to meet global service standards. Therefore, the question of understanding the needs and wishes of consumers in eating unique dishes, using modern technologies, which is of significant importance for hospitality enterprises due to the formation of their culinary brand, is relevant. The possibility of introducing the latest restaurant business in the hospitality industry to expand catering services and attract consumers of hotel services in the restaurant business of the hotel enterprise is analyzed. The main directions of molecular technologies to meet the needs of consumers in extravagant and extraordinary technologies that meet the requirements of all lovers of gourmet dishes, including gourmets. Given the peculiarity of molecular technologies, ensuring the proper structural and mechanical properties of ready meals is impossible without the use in their recipes of food additives of natural origin and raw materials with emulsifying and gelatinizing properties, which are able to regulate the consistency and texture in order to obtain the required effect. The use of food additives agar-agar, carrageenan, sodium alginate, calcium chloride, egg powder, glucose, lecithin, trimolin, xanthan not only perform the role of improvers, but also have an important physiological value for the human body and contribute to improving the nutritional value of dishes with their use. Practical significance. The introduction of the main directions of molecular gastronomy in the restaurant business of the hotel company will expand the range of unique specialties on the menu, and in particular provide them with health, ensure a high level of organization of the technological process, reduce production losses and increase potential consumers of restaurant services.
THE IMPACT OF THE HISTORICAL ASPECT ON THE DEVELOPMENT AND POPULARITY OF THEME PARKS IN THE WORLD (CASE WALT DISNEY COMPANY)
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Masliak Petro , Slyzkii Andrii ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: September 2023

The article's purpose is a temporal analysis of the origin of the theme park as a transformational destination, and its progressive development from "pleasure gardens" to a modern high-tech theme park with entertainment, recreational and educational functions that meets all the needs of the contemporary recreationist. Methods and methodology in the study of this topic, which were used for the practical analysis of this topic (historical aspect and influence of external and internal factors) have a systematic approach and a set of methods in particular: - methods of collecting and analyzing information, namely the collection of theoretical and analytical information on the history of the emergence and transformation of recreation parks, the formation, and improvement to their current state; - methods of analysis and synthesis of information, processing of collected materials, data optimization, and formation of own conclusions on the spread and popularity of international parks. The results. The article analyzes the stages of the formation of theme parks as destinations for recreation, which over time gained popularity and transformed under the influence of the needs of recreationists, and economic and technological changes. The problems that companies have during the design and creation of theme parks, as well as the way of their popularization in Europe in the example of Disneyland in Paris, are considered and illustrated. Practical significance. Consumers were constantly looking for a holiday that would combine interactive adventures, comfortable conditions, technological curiosities, films and TV shows, and sci-fi topics. Theme parks today demonstrate the highest rates of attendance and interest of tourists in their product, but analyzing the historical stages on the way to the development of theme parks, we trace the negative attitude towards new projects in Europe. Therefore, the analysis of historical stages is important when creating new projects, to take into account similar experiences, the development of image marketing, and the choice of a common topic when creating a park. In general, the future of theme parks depends on the economic conditions and quality of services provided, the level of epidemic diseases, but as a tourist product it has very attractive prospects, which is confirmed by the financial reports of companies. The concept of theme park development consists of intensive improvement, and the introduction of the latest technologies and refers to the most promising areas in the development of the tourism sector, which is of interest to research in order to further implement knowledge for new projects.
Impacto de las fuentes de energía renovable en la estabilidad de la tensión y técnicas de evaluación
Authors: Mesa-Call Julián , Villa-Acevedo Walter , López-Lezama Jesús M.
Published: September 2023

La proliferación de fuentes de energía renovable y su impacto en los sistemas de potencia hacen necesaria la realización de estudios para asegurar la buena operación del sistema de potencia. Este artículo indaga investigaciones recientes sobre el impacto de las fuentes de energía renovable sobre la estabilidad de tensión y nuevos métodos empleados para evaluar esta estabilidad. Se estudian efectos de la generación de energía solar y eólica tanto individual como colectivamente, junto con otros modelos de inversores a través de los cuales se conectan fuentes de energía renovable a los sistemas de transmisión o redes de distribución. Además, se resaltan los resultados categorizándolos en un enfoque determinístico y probabilístico.
Shot-gather Reconstruction using a Deep Data Prior-based Neural Network Approach
Authors: Rodríguez-López Luis Miguel , León-López Kareth , Goyes-Peñafiel Paul , Galvis Laura , Arguello Henry
Published: September 2023

Seismic surveys are often affected by environmental obstacles or restrictions that prevent regular sampling in seismic acquisition. To address missing data, various methods, including deep learning techniques, have been developed to extract features from complex information, albeit with the limitation of requiring external seismic databases. While previous works have primarily focused on trace reconstruction, missing shot-gathers directly impact the seismic processing flow and represent a major challenge in seismic data regularization. In this paper, we propose DIPsgr, a seismic shot-gather reconstruction method that uses only the incomplete seismic acquisition measurements to estimate their missing information employing unsupervised deep learning. Numerical experiments on three databases demonstrate that DIPsgr recovers the complete set of traces in each shot-gather, with preserved information and seismic events.
Formation of Polyacetylene Films on Copper Substrate by Abnormal Glow Discharge
Authors: Sarmiento-Santos Armando , Gómez-Castaño Jovanny A. , Alvarez-Luna Brenda , Redondo-Lancheros William , García-Zúniga Jaime
Published: September 2023

The formation of polymeric films by plasma has become an alternative for the coating of metallic materials that require varying their surface characteristics and improving their resistance to corrosion; because by this method it is possible, in principle, to polymerize any gaseous hydrocarbon. In this work, the study of the formation of acetylene polymer films on a copper substrate, previously treated in an abnormal luminescent discharge regime in argon-hydrogen atmosphere, is presented. The polymeric formation was carried out in a continuum current abnormal glow discharge in an atmosphere of 60% Ar, 35% H2 and 5% C2H2 at a pressure of 2 Torr, at a temperature of 600 °C and with deposition times between 5 and 120 s. The structural and morphological analysis of the polymeric film deposited at different temperatures was performed by Infrared Spectroscopy and Scanning Electron Microscopy. Additionally, a characterization of the materials was carried out using corrosion resistance analysis.
Circular RNA METTL15/miR-374a-5p/ESCO2 axis induces colorectal cancer development
Authors: Guo Feng , Luo Yang , Ye GuangYao , Tang WeiJun
Published: September 2023

This study investigated the biological role and mechanism of circMETTL15 in colorectal cancer (CRC). Cancer tissues and matched adjacent normal tissues were collected. CircMETTL15, miR-374a-5p, and ESCO2 levels were detected by RT-qPCR and Western Blot. LoVo cells were selected for loss- and gain-of-function assays and rescue assays. Cell proliferation was detected by CCK-8 and colony formation tests, cell apoptosis and cell cycle were detected by flow cytometry, cell migration and invasion were detected by Transwell assay, and protein expression of ki-67, E-cadherin, N-cadherin, and cleaved caspase-3 was detected by Western blot. Through bioinformatics analysis and verification assays, the targeting relationship between circMETTL15, miR-374a-5p, and ESCO2 was studied. The results suggest that circMETTL15 was a stable circRNA that was highly expressed in CRC tissues and cells and was associated with tumor size, higher TNM staging, and lymph node metastasis in CRC patients. Functionally, knocking down circMETTL15 inhibited the proliferation, migration, invasion, and EMT of LoVo cells, and induced apoptosis. Overexpression of circMETTL15 showed the opposite effect. The effects of knockdown or overexpression of circMETTL15 on the biological behavior of LoVo cells were reversed by knockdown of miR-374a-5p or knockdown of ESCO2, respectively. Mechanistically, circMETTL15 acts as a ceRNA for miR-374a-5p to regulate ESCO2 expression, thereby promoting the biological behavior of LoVo cells. In conclusion, the results of this study reveal the role of circMETTL15 in CRC and the underlying molecular mechanism, which provides potential data support for the development of future CRC drugs.
Long noncoding RNA LGALS8-AS1 promotes angiogenesis and brain metastases in non-small cell lung cancer
Authors: Zhong Jian , Wang Bo
Published: September 2023

Brain metastases (BM) are associated with poor prognosis in patients with non-small cell lung cancer (NSCLC). Considering that, LGAS8-AS1-mediated progression of BM was probed in NSCLC. The clinical characteristics of 60 NSCLC patients (30 without BM and 30 with BM) were analyzed. NSCLC patients with BM had higher levels of LGALS8-AS1 than NSCLC patients without BM. Depleting LGALS8-AS1 prevented NSCLC cell proliferation, migration, invasion, and angiogenesis in vitro, and NSCLC tumorigenesis and BM in vivo. LGALS8-AS1 targeted miR-885-3p to mediate Fascin actin-bundling protein 1 (FSCN1) expression. Restoring miR-885-3p inhibited NSCLC growth, angiogenesis, and BM, and FSCN1 induction rescued the performance of LGALS8-AS1 depletion on NSCLC cells. Our results provide new insights into LGALS8-AS1-mediated NSCLC metastasis and suggest that LGALS8-AS1 may be a useful biomarker for identifying NSCLC with metastatic potential.
Chest Examination with Wireless Technology in a Patient with Fibrotic Disease: A Pilot Case Report
Authors: Scaramozzino Marco Umberto , Giovanni Sapone , Romeo Plastina Ubaldo , Levi. Guido
Published: September 2023

Physicians use auscultation as a standard method of thoracic examination: it is simple, reliable, non-invasive, and widely accepted. Artificial intelligence (AI) is the new frontier of thoracic examination as it makes it possible to integrate all available data (clinical, instrumental, laboratory, functional), allowing for objective assessments, precise diagnoses, and even the phenotypical characterization of lung diseases. Increasing the sensitivity and specificity of examinations helps provide tailored diagnostic and therapeutic indications, which also take into account the patient's clinical history and comorbidities.

Several clinical studies, mainly conducted in children, have shown a good concordance between traditional and AI-assisted auscultation in detecting fibrotic diseases. On the other hand, the use of AI for the diagnosis of obstructive pulmonary disease is still debated as it gave inconsistent results when detecting certain types of lung noises, such as wet and dry crackles. Therefore, the application of AI in clinical practice needs further investigation.

In the case we present, data integration allowed us to make the right diagnosis, avoid invasive procedures, and reduce the costs for the national health system; we show that integrating technologies can improve the diagnosis of restrictive lung disease. Randomized controlled trials will be needed to confirm the conclusions of this preliminary work.
A Rare Case of Mild Spontaneous Pneumomediastinum Associated with Asthma Exacerbation.
Authors: Scaramozzino Marco Umberto , Giovanni Sapone , Guido Levi , Ubaldo Plastina Romeo
Published: September 2023

Introduction:
The presence of free air within the mediastinum, that is not associated with trauma, is known as spontaneous pneumomediastinum [1].
The disease was originally described by Rene Laennec in 1819. The word spontaneous was introduced by Hamman later in 1939.The condition can result from an injury that leads to air leakage into the mediastinum from the lung . Spontaneous indicates that it is encountered in patients with underlying lung diseases or without any medically relevant conditions as compared to that secondary pneumothorax that results from trauma [2]. The pathophysiological mechanisms underlying pneumomediastinum are six:
1) Direct mechanism
2) Hamman-Macklin mechanism
3) Subfascial route (secondary to pneumothorax or chest wall injury)
4) Subserosal route:
Interculturalidad desde las acciones cotidianas en el aula
Authors: Bustamante Álvarez Clarivel , Holguín Guisao María Isabel , Alzate Alzate Natalia Andrea
Published: September 2023

Este artículo presenta los resultados de una investigación realizada en el aula escolar con niños y niñas del grado quinto de primaria de una institución educativa de corte pública de la ciudad de Medellín. Espacio que se encuentra atravesado por dinámicas relacionales complejas, al ser tensionado y problematizado por la diversidad cultural. La investigación de corte cualitativo asume una postura teórica etnometodológica, dinamizada a través de técnicas interactivas de recolección de información. Como resultado se encuentra que hay una pérdida del vínculo familia-escuela, esto porque el contexto escolar tiende a convertirse en el único lugar donde le niño puede construir una idea de cultura y relacionamiento social, y valores como la tolerancia, el respeto, la aceptación por el otro quedan circunscritos a la experiencia de aula.