bluuebunny/crossref_metadata_2025 huggingface dataset:
Machine Learning in FMCG - How Social Listening, Big Data, and AI Apply in the Business Decision Process
Authors: Chunyu Yau Peter
Published: April 2022

Without a machine, human beings cannot process the massive data volume produced by us nowadays for business analysis purposes. Being part of the critical decision-making process in the commercial sector, the usage and role of Big Data, especially those collected from social listening are getting important: how a company listen to the true voices from a group of genuine customers and avoid those misleading, fake comments generated by the robot, to enhance the efficiency on measuring competitor's performance towards their marketing return compared to the investment (MROI), is critical and more challenging.In this paper, we will discuss various analytical methodologies from the angles of business and technological viewpoint: what decision-makers want from social media, what kind of information are they looking into, how visualisation provides instant insights and what kind of system design provides enough interaction to the decision-maker. We will investigate the real-world challenges and difficulties: how the data inconsistency affects the computational analysis, what kind of obstacles was facing in the existing product design in the market. Finally, we will conclude the used machine learning techniques that can address the mentioned business problems, including the successful rate, accuracy and various efficiency level in the studied samples.
On the Product Service System Design of Diabetes Management for Patients
Authors: Mo Zhiwei
Published: April 2022

The increasing number of chronic patients is still a problem for the Italian medical system. In the age of digitalization, digital technology offers many opportunities for helping these patients solve problems, through advanced technologies such as the Internet of Things, big data, and cloud computing, smart devices can be used to collect and analyze the health information of diabetic patients, and transmit it to medical institutions in a form of visual models for obtaining reasonable treatment recommendations timely. This smart product can analyze the patient's health data in real time, meet the needs of the patient, and facilitate the connection between the patient and various medical institutions. This paper studies the product service system centered on diabetic patients, designs a smart device with blood sugar testing, and provides an Italian localized solution.
A Landmark Detection and Iris Prediction Dataset for Gaze Tracking Research
Authors: Thaman Brett , Caporusso Nicholas , Cao Trung
Published: April 2022

Gaze tracking has become an established technology that enables detecting the position of the eyes and using it for estimating where the user is looking. In the last decades, gaze tracking has been realized primarily with dedicated devices utilizing infrared (IR) sensors, though the requirement of adopting specific hardware has limited gaze tracking and its use in potential large-scale applications. In the last decade, several research groups have pursued the development of gaze tracking solutions based on computer vision and traditional RGB cameras such as webcams embedded in portable computers and mobile devices. Unfortunately, previous studies have shown that gaze tracking systems based on RGB cameras have significantly lower accuracy, are not suitable for tasks that require precise user control, and require further research and development. Recently, TensorFlow released a landmark detection library that predicts the location of key points of the human face, including the position of the eyes. The algorithm outputs approximately 500 features in which each point is represented as a series of coordinates on a three-dimensional space. Although TensorFlow’s landmark detection algorithm could potentially be utilized for gaze tracking tasks, the number and complexity of its features make it unpractical to use it for real-time gaze prediction without further feature extraction and dimensionality reduction. In this paper, we introduce and discuss a dataset designed for stimulating screen-based gaze tracking research aimed at replacing traditional IR devices with standard RGB cameras. Our objective was to label the features estimated by TensorFlow’s landmark detection and iris prediction model with the actual location of the user’s gaze on a screen. To this end, we collected data from 30 users who were involved in gaze tracking tasks. Each sample in our dataset includes all the features of TensorFlow’s landmark detection and iris prediction model and two different labels representing (1) the actual gaze location acquired with a dedicated IR sensor, and (2) a reference point. In this paper, we detail the data collection software and procedure, we describe the dataset, and we discuss its potential use in advancing gaze tracking research.
Smartphone based accurate touch operations on an AR desktop
Authors: Miki Masahiro , Takimoto Munehiro , Kambayashi Yasushi
Published: April 2022

Recently, we have seen and used touch-based operations as a popular interface for smart phones and tablet PCs. As the interface, we interact with a device through touching the physical surface of the screen. The touch-based manner gives simple and intuitive interface for users but is not always convenient for several users to operate a single device cooperatively. Also, in some cases, manipulating a screen without direct touch is rather desirable. Because touchless operations prevent viruses from infecting the users. It is especially true in the current situation of COVID-19 pandemic. In order to implement such touchless interfaces, researchers have proposed augmented reality (AR) based desktops or keyboards. Most of such AR based interfaces, however, require interactions with virtual objects in the air, which are not accurate. Therefore, such interfaces are rarely used in practice. In this paper, we propose a new operation manner of AR based desktop. In our operation manner, the user can perform operations on his or her smartphone as an AR object displayed in the virtual space on the screen. The smartphone has its own AR marker, which specifies the coordinate of it, and gives the reference point for displaying the cursor. The cursor is always displayed at the center of the smartphone and represents the home position of fingers. Thus, even if the virtual screen is displayed with wide size such as one of a desktop PC, a user moves his or her fingers along with his or her smartphone to the location of a specific icon on the screen, and then can give any operations constituting of single touch or double touch, such as tapping, flicking, pinching or swiping. Notice here that the user physically operates the smartphone although he or she feels like operating the virtual screen through directly touching it. The physical operations on the smartphone contribute to intuitive manipulation and providing actual feelings. They also help the users perform accurate operations. In order to demonstrate the effectiveness of our manipulation manner, we have implemented a prototype system and have conducted numerical experiments on it. The prototype system recognizes an AR marker attached on the users’ smartphones by external web cameras and decides their locations, so that the user can apply any operations of fingertips to the AR objects on the virtual screen. In the experiment, the screen is displayed in front of each user, who can identify and synchronize movement of his or her smartphone with the cursor. Once the cursor reaches the target position, each user can apply one of the following six operations: tap to launch apps, double-tap/drag to move app icons, pinch-out/pinch-in to zoom in and out, and flick to create or switch screens. We focused how the users could grasp the touch operation intuitively and manipulate the system as they intended. As the results, we have confirmed that the users can feel as if they touch the actual screen in the virtual space and manipulate the prototype system as intended.
Distributed Ledger Technology in Autonomous Driving: A Security Protection Layer
Authors: Raemy Nicola , Kondova Galia
Published: April 2022

Cybersecurity in autonomous driving is of utmost importance since a hacked self-driving car could turn into a remote-controlled weapon. Appropriate measures must be taken and implemented to ensure future road safety. The substantially shorter renewal cycles in the hardware (e.g., sensors, computer hardware) and especially software domain compared to the current service life of a vehicle represent a further challenge The use of blockchain technology could enhance security in autonomous driving and thus reduce cybersecurity risks. This paper studies current developments of Swiss pilot projects in autonomous driving and discusses existing solutions for increasing safety of autonomous driving through blockchain.
Psychophysiological parameters for emotion recognition – Conception and first evaluation of a measurement environment
Authors: Birkle Jonas , Weber Ruben , Möller Knut , Wagner-Hartl Verena
Published: April 2022

Emotions are of great importance for human interaction. The recognition of emotions is an essential basis for the social interaction of people, relevant at all levels of human interaction. However, the ability varies greatly among people, even to the point of a pathological deficit in autism (e.g., symptoms of "social blindness"). Furthermore, it is also an interesting topic in the current COVID-19 pandemic-situation with its restrictions regarding personal contacts and the resulting increase of digital contacts through online communication. For this reason, the measurement of emotions is of great interest for a wide variety of applications and, in particular, for product design or the development of trainings (e.g., for children with autism, leaders and managers, employees working in virtual teams etc.). The presented paper focuses on a concept and first evaluation of a measurement environment. Based on the objective emotional assessment (OEA) of Boucsein and his colleagues, a multidimensional approach was chosen for the developed concept. The studied psychophysiological measures were: cardiovascular (ECG) and electrodermal activity (EDA) as well as the forearm and neck electromyogram (EMG). In addition, the facial expression was recorded via camera. The results of a first evaluation (different tasks like a short game, a backward counting task, or thinking of different emotional contents) show, that the combination of the different measures was successful and promising for the use in further research. The study was able to show a need for improvement with regard to the derivation of the ECG (chest strap vs. adhesive electrodes). The design of the measuring environment can be seen as successful regarding the combination of the different psychophysiological measures and devices. In the future, an expansion with additional parameters such as pulse volume amplitude (PVA) or eye tracking will be considered.
Creating Tactile Interaction Surfaces for the Origo Steering Wheel Concept using CWI and EHWs
Authors: Farooq Ahmed , Sinivaara Hasse , Laaksonen Mikko , Virtainen Hanna , Hippula Arto , Surakka Veikko , Raisamo Roope
Published: April 2022

As the automotive industry transitions to electric and autonomous vehicles (SAE 2-3) more and more information needs to be reviewed by the driver in real-time. Conventional information presentation techniques are not ideal for reviewing this type of information as it lacks multimodal and cross modal presentation. Haptics, one of the key interaction modalities, is often over-looked as it is considered non-functional in a vibration heavy environment, such as a moving vehicle. However, modern techniques of generating, medi-ating, and delivering tactile feedback have greatly improved in the last five years. Localizing techniques such as Constructive Wave Interference (CWI) and mediation technique of Embedded Haptic Waveguides (EHWs) can be combined to create reliable and consistent tactile output in even the most challenging environments. In this research authors utilize these techniques to create tactile feedback zones on the steering wheel, which can be used to relay haptic signals to the driver with little to no visual demand. These zones were 3D-printed onto an intelligent adaptive (Origo) steering wheel. Authors com-pared the efficiency of the Origo Wheel with the onboard wheel of a Porsche Cayenne, using identical actuation components while the vehicle was being driven on the Nokia Tires Track. Compared to the Porsche Cayenne's original steering wheel, the Origo wheel was able to mediate actuation to the driver’s point of contact more efficiently which yielded better driving and secondary task performance. Using the Origo wheel was also rated to have required low-er cognitive load in completing the IVIS tasks in the moving vehicle.
The Application of the Aesthetic Measures of Interface Layout in Drawing 2.5D Graphic
Authors: Zhu Zhiman , Wang Fei , Hu Ruoyu , Peng Ningyue , Xue Chengqi
Published: April 2022

2.5D graphic or Isometric graphic, as a common graphic expression method, has been fully developed in 2021 and has become a prevalent UI illustration element. With the rapid development of computer technology, many two-dimensional graphic images are analyzed and calculated digitally, and integrated data are efficiently and automatically generated. Aesthetic evaluation starts from subjective perceptual evaluation to rational digital calculation. In order to better calculate the aesthetic evaluation of 2.5D graphic, combining various aesthetic evaluation researches in the two-dimensional plane and the existing aesthetic index evaluation methods, this paper puts forward the idea of applying the two-dimensional plane evaluation method to the element layout 2.5D graphic. The research refers to the 13 aesthetic measures in the interface layout proposed by the NGO. In this study ,we selects the 2.5D graphic in 11 existing web pages from the design website as the samples, and extracts two-dimensional layout diagram of these samples. Then the beauty index calculation of the samples layout data found that the 13 aesthetic measures all have significant characteristics. In the experimental part, this study chose to take the measure of balance in the aesthetic measures as an example. By analyzing the numerical setting of the calculation formula, we designed 16 experimental as samples, and 10 design-related practitioners are recruited as subjects for aesthetic evaluation. Finally, the standardized data is fitted with manual evaluation results. The experimental results show a certain similarity with the previous sample data calculations, which proves the applicability of this evaluation method and lays the foundation for the standardized calculation of the beauty of 2.5D graphic. Future research can be carried out on this basis, it is necessary to study a set of overall aesthetic evaluation methods of the system, which can be more intuitively applied to the evaluation and generation of 2.5D graphic aesthetics. When 2.5D material forms a unified material library, the computer can automatically perform aesthetic calculations and layouts to generate the required 2.5D graphic based on the needs and user aesthetics, reducing labor costs and ensuring the stable quality.
Are answers more important than questions? Planning an empathy design innovation course for young students
Authors: Qiu Jing , Li Jingyang , Xu Zhao , Huang Ruonan , Wang Ruikang , Wu Lingjie , Wu Xiaojian , Yang Fan , Zhang Zhejun , Leifer Larry , Liu Wei
Published: April 2022

This paper presents the planning of an innovation course for elementary school students. The course is designed and organized by the Beijing Normal University in collaboration with the China Soong Ching Ling Science and Culture Centre for Young People. This course aims to foster children's empathy and creative thinking. There are three core teaching phases: theme exploration, design expression, and prototyping. In addition, the research team applies NeuroDesign techniques (i.e., fNIRS) to quantitatively measure students' development of empathy and innovation to assess the effectiveness of teaching and learning. Educators would refer to this planning for designing other educational courses on fostering creativity.
A user-centred terminology for existing and upcoming ICT devices, services and applications
Authors: Boecker Martin , Qawasmeh Omar , Darmois Emmanuel
Published: April 2022

Users, unfamiliar with the terminology, technical meaning or intended functionality of mobile ICT (Information and Communications Technology) devices and services may be reluctant to use them and miss out on their potential benefits. This also prevents users from exploiting the true potential of ICT and hinders the uptake and use of services, including those of societal relevance. We present an alternative focusing on improving the overall user experience and accessibility through the provision of recommendations for a harmonized terminology, covering more than 500 basic, commonly used ICT features in 19 European languages including English, French, German, Italian and Spanish. Technical Committee Human Factors (TC HF) of the European Telecommunication Standards Institute (ETSI) has initiated this ongoing work, to develop a freely available ETSI document (ETSI Guide EG 203 499 update to be published in the first half of 2022). The poster will present the method used for developing the terminologies and will provide examples of the terminologies to be published in the ETSI Guide.This work is undertaken by ETSI and co-funded by the European Commission (EC) of the European Union (EU) and the European Free Trade Association (EFTA).
Cognitive Mimetics for Designing Intelligent Industrial Systems: Case Next-Generation Diary
Authors: Karvonen Antero , Kuusisto Olli , Saariluoma Pertti
Published: April 2022

A key problem with intelligent industrial processes is that the relevant systems, such as digital twins or cyber–physical systems, require knowledge to perform their operations. Currently, much of that knowledge is in the human domain; it is largely tacit and shared informally. Here, we sketch out an idea for an intelligent industrial diary, building on the concepts of cognitive mimetics and human digital twins and focusing on ontology-related aspects of the system. We ask how human knowledge and knowledge of humans can be captured and operationalized to provide the necessary currency and basis for intelligent technology and its design. Our idea is derived from empirical research on the concept of a “next-generation diary” for pulp mills. The broader idea is that intelligent industrial diaries could become a key focal point for accumulating the knowledge needed for intelligent technology, thereby embodying the main ideas in cognitive mimetics.
WIRELESS CHARGING OF BATTERY
Authors:   Government College of Engineering, Nagpur, Surjuse Rajesh
Published: April 2022

In reaction to the depletion of natural resources, electric vehicles offer a viable alternative. Practical and dependable methods to charge EV batteries are crucial in order to boost the usage of EVs in daily life, and wireless power transfer (WPT) is being investigated as a solution to charge batteries. In this project, a wireless charger prototype system is built and implemented. The necessity for a cable and plug charger, galvanic separation of the onboard electronics, weight, and cost of this charger, and massive energy storage system (ESS) packs are all present in today's electric vehicles. This paper has designed and developed an antenna system suitable for vehicles using resonant magnetic coupled wireless power transfer technology to an electric vehicle charging system. The use of WPT in EVs provides a clean, convenient and safe operation. At the core of the WPT systems are two coils namely primary and secondary. For the safe and efficient transfer of energy the rated power, both sides have to be tuned by resonant capacitors. The selection of operating frequency is a key criterion for all applications as it affects the size and dimensions of the coils and the selection of the components for the power electronic circuit. Resonant wireless transmission systems for vehicle charging technology are being developed. Keywords— Wireless power transmission(WPT)
Extensión de la doctrina de la discriminación por asociación a otros derechos fundamentales
Authors: Sánchez Trigueros Carmen
Published: April 2022

Estudio de nueva sentencia que aplica la figura de la discriminación por asociación al supuesto de una trabajadora despedida como represalia por la actividad reivindicativa y judicial de su pareja.

Analysis of a new judgment that contemplates the legal form of discrimination by association of a worker that was dismissed as a reprisal for her partner's claiming and judicial activity.
Ámbito jurisdiccional del orden social: competencia desleal a la empresa a través de sociedad mercantil
Authors: García Murcia Joaquín
Published: April 2022

El orden jurisdiccional social no sólo es competente en los casos de competencia desleal de los trabajadores hacia su empresa sino también en aquellos casos en los que esa conducta se desarrolla a través de una sociedad constituida por antiguos trabajadores de la misma. La contradicción entre sentencias que actúa como presupuesto del recurso de casación para unificación de doctrina puede apreciarse en lo relativo a la competencia del orden jurisdiccional social respecto de otros órdenes jurisdiccionales.

Social courts are competent for handling cases of unfair competition of workers against the actual employer, but also in those cases in which this conduct is developed through a society constituted by former workers of the undertaking. Access to the appeal before the Supreme Court in these situations requires a discrepancy between judgments regarding the scope of the jurisdiction of labour courts.
El principio de reparación íntegra del daño en la asistencia sanitaria del accidente de trabajo y vigencia
Authors: López Cumbre Lourdes
Published: April 2022

Ante la exigencia de ofrecer una asistencia sanitaria que garantice la reparación del daño ocasionado por accidente de trabajo surge la necesidad de establecer límites. La dispensación de prótesis que sustituyan la parte del organismo dañado puede permitir la mera reparación o la mejor reparación. Las normas básicas internacionales avalan la opción por esta última.

In view of the requirement to offer health care that guarantees the repair of the damage caused by an accident at work, there is a need to set some limits. The dispensing of prostheses that replace the part of the damaged organism may allow for mere repair or the best repair. International basic standards support the latter option.
¿El trasplante renal impide promocionar en el Cuerpo de Bomberos de la Administración Pública?
Authors: Areta Martinez María
Published: April 2022

Un bombero trasplantado de riñón puede promocionar en el Cuerpo de Bomberos de la Comunidad de Madrid si resulta acreditado que el trasplante no impide ni dificulta el desempeño de las tareas propias de la Categoría a la que aspira. El cuadro médico de exclusiones (cuadro de permanencia) no opera de forma automática.

Firefighters in the Community of Madrid who have undergone kidney transplants are not automatically prevented from being promoted in the squad as long as it is officially recognized that the transplant does not hinder them from carrying out the duties specific to the position to which they are applying for. The list of medical conditions that excludes entry into the firefighter squad does not operate automatically
¿Se considera procedente la extinción objetiva (por causa técnica) de un trabajador que ha sido sustituido por un robot?
Authors: Arias Domínguez Ángel
Published: April 2022

Una empresa hotelera adquiere un programa informático que es capaz de realizar las reclamaciones (y conciliación) de cobros a los proveedores de manera prácticamente automática, sin necesidad de la intervención humana. La empresa procede a extinguir por circunstancias objetivas (por causa técnica) el contrato de trabajo de la trabajadora que se encargaba de esta encomienda laboral con un programa informático menos sofisticado. Se trata de determinar si dicha extinción se encuentra amparada por la causa técnica recogida como circunstancia objetiva en el Estatuto de los trabajadores.

A hotel company acquires a computer program that is capable of making claims (and reconciliation) of charges to suppliers virtually automatically, without the need for human intervention. The company proceeds to extinguish due to objective circumstances (for technical reasons) the employment contract of the worker who was in charge of this labor assignment with a less sophisticated computer program. It is about determining whether said extinction is protected by the technical cause collected as an objective circumstance in the Workers' Statute.
¿Puede ser considerada persona con discapacidad la trabajadora que tiene la consideración de especialmente sensible frente a los riesgos derivados del trabajo?
Authors: Arias Domínguez Ángel
Published: April 2022

Se resuelve una cuestión prejudicial en la que cuestionaban dos circunstancias. Si, en primer lugar, podía considerarse discapacitada a la trabajadora que tenía reconocida la consideración de especialmente sensible a los riesgos derivados del trabajo. Y si, en segundo lugar, los criterios implementados empresarialmente para la articulación de un despido colectivo por causa económica, técnica, organizativa o de producción, eran discriminatorios precisamente por emplear parámetros que tenían en consideración variables laborales de difícil consecución por una trabajadora especialmente sensible a los riesgos laborales que, además, había acumulado bajas laborales por esta circunstancia en el período antecedente tenido en consideración para la extinción objetiva.

A preliminary ruling is resolved in which they questioned two circumstances. If, in the first place, the worker who had the consideration of being especially sensitive to the risks arising from work could be considered disabled. And if, secondly, the criteria implemented by companies for the articulation of a collective dismissal for economic, technical, organizational or production reasons, they were discriminatory precisely because they used parameters that considered labor variables difficult to achieve by a worker especially sensitive to the occupational risks that, in addition, had accumulated labor losses for this circumstance in the previous period taken into account for the objective extinction.
La infracción de norma en el recurso de casación (Civil y Social).
Authors: Sempere Navarro Antonio V.
Published: April 2022

La STS-CIV 629/2019 desestima el recurso de casación interpuesto porque no se ha citado norma alguna como infringida, tal y como exige la Ley de Enjuiciamiento Civil. Al hilo de esta sentencia, se examina el modo en que la cuestión se aborda en el ámbito del recurso de casación dentro de la jurisdicción social.

STS-CIV 629/2019 dismisses the appeal because no rule has been cited as infringed, as required by the Civil Procedure Act. In line with this judgment, it is examined the way in which this issue is addressed in the field of the appeal within the labour courts.
Elaboración del calendario y fijación de los turnos de vacaciones en empresas sin representación de los trabajadores.
Authors: Castro Argüelles María Antonia
Published: April 2022

La STS 715/2019 considera conforme a derecho el calendario y los turnos de vacaciones establecidos por el empresario, en una empresa sin representantes de los trabajadores, al contar con la conformidad por escrito de la mayoría de los trabajadores y ser los que se aplican desde hace años.

The Judgment of the Supreme Court 715/2019 considers according to law the calendar and vacation shifts established by the employer, in a company without workers' representatives, by having the written agreement of the majority of workers and being the ones that have been applied for years.
¿Debe extenderse el permiso por matrimonio a las parejas de hecho?
Authors: Sánchez Trigueros Carmen
Published: April 2022

Interpretación del permiso "por matrimonio" del artículo 58 a) del III Convenio Colectivo de la Sociedad Estatal Correos y Telégrafos. Pretensión de que la pareja de hecho sea equiparada a tales efectos. La sentencia analizada concluye que los criterios de interpretación de los convenios colectivos conducen a determinar que el derecho allí previsto únicamente se aplica en los casos de matrimonio. Hay un Voto Particular preconizando la interpretación flexible y teleológica de la norma, atendiendo a la realidad social.

Interpretation of the "by marriage" permit of article 58 a) of the III Collective Agreement of the State Postal and Telegraph Society. Pretension that the de facto couple be equated to such effects. The judgment analyzed concludes that the criteria of interpretation of collective agreements lead to determine that the right provided therein only applies in cases of marriage. There is a Special Vote advocating the flexible and teleological interpretation of the norm, attending to the social reality.
El concepto de "profesión habitual" en orden a declarar la incapacidad permanente de un bombero que pasa a segunda actividad.
Authors: Areta Martinez María
Published: April 2022

Un bombero, que pasa a segunda actividad tras sufrir un accidente de tráfico con secuelas, puede ser declarado en incapacidad permanente parcial para la profesión habitual. En tal caso, el bombero no puede realizar las funciones del servicio ordinario que, junto a las más livianas de la segunda actividad, forman su "profesión habitual".

A firefighter who suffers the permanent after-effects of a traffic accident and who has therefore transitioned to an administrative role can be declared to have a partial permanent disability with regards to their normal work. In these cases the firefighter is no longer capable of carrying out the functions of their primary role. Their normal work now encompasses both the lighter administrative tasks together with the former primary functions.
THE STRUCTURE OF UNITED NATIONS AND ITS MANDATE: A REVIEW
Authors: DUGURI USMAN SAFIYANU , SALLEH MOHD AFANDI , HASSAN ISYAKU
Published: April 2022

The creating of United Nations is to keep global security and international peace. The United Nations Charter outlined detailed guidelines for resolving international disputes and foreshadowed the potential of the UN providing collective security. The United Nations has six organs: the General Assembly, Security Council, Economic and Social Council, Trusteeship Council, International Court of Justice, and Secretariat United. There are fifteen specialised agencies, four linked organisations as well as three convention secretariats and two United Nations trust funds affiliated with the United Nations. This paper systematically reviews and examines the structure of United Nations and its mandate within the framework of international relations. finally, the study found that the structure of United Nations has contributed a lot regarding to international security and peace, however, there is need for the notion behind veto power to be restructured due to the interest of fulfilling the Council’s purpose and goals.
THE STUDY PROGRAMME OF DANCE PEDAGOGY AND ITS RENEWAL CONTEXTS
Authors: MONTVILAITE SIGITA , PROKUROTIENE RASA , KANCAUSKAITE EGLE
Published: April 2022

The article discusses the study programme of dance pedagogy and its renewal contexts. Additionally, the study analyzes dance programmes of Scandinavian countries, which are well evaluated and appreciated. The dance programmes are analyzed based on comparison with the situation in Lithuania, i.e. study programme of dance pedagogy at Vilnius College (University of Applied Sciences), which has a purpose to educate and prepare a pedagogue who is capable to attain education results provided in general education programs, to provide scholars with an opportunity to develop and educate the basis of moral, social, cultural, and civic qualities, acquire general and specific competencies and get the chance to try these competencies in various professional activities, so as to decide the prospects of future career. With the aim to evaluate the quality of the study programme of dance pedagogy in Scandinavia and Lithuania, its efficiency, effectiveness, and compliance with European standards, the documents that regulate teacher training, and course descriptions are analyzed. In addition, it is attempted to examine whether graduates of these countries are satisfied with study programmes and wherewith the programme is special. While analyzing the content of study programmes, the opinion and evaluation of graduates are of particular importance seeking continuous improvement while applying new and relevant disciplines.
A REVIEW ON APPLICATIONS OF DEXMEDETOMIDINE (BXCL501) IN CNS DISORDERS
Authors: Chabukswar Anuruddha , Abhyankar Shalaka , Nanaware Rajesh
Published: April 2022

A drug that subdues exhilaration and produces a calming effect in the subject without necessarily inducing sleep is referred to as sedative. The main system for action of these drugs is the Central Nervous System (CNS). Sedatives are slow working drugs with a levelled dose response curve. They act by modifying nerve responses in CNS to the brain which slows down brain activity thus relaxing the body. Gamma-amino-Butyric acid (GABA) is neurotransmitter which is responsible for retarding the brain functioning and sedatives increase the activity of GABA to produce more effect on the brain activity. Mostly sedatives are used to treat sleep disorders, pain or as anaesthetics. Opioids are sedatives used to treat pain, but long-term usage of these drugs leads to dependency and addiction which may be a challenge to treat. People experience withdrawal symptoms like nausea, vomiting, anxiety, insomnia and/or irritability along with seizures and loss of consciousness in some extreme cases. BXCL501 is a formulation of Dexmedetomidine used to treat agitation and symptoms of opioid withdrawal. The drug is designed in such a manner that it reduces agitation but does not produce excessive sedation. The RELEASE clinical trial of “bioxcel therapeutics” lead to the use of this drug to treat or retard opioid withdrawal symptoms and agitations. This article is aimed at reviewing and summarising existing data concerning the synthesis, chemical taxonomy, properties, mechanism of action, pharmacokinetic-pharmacodynamic profile, side effects, interactions, toxicology of dexmedetomidine.
ISOLATION, CHARACTERIZATION AND EXPLORATION OF THE BIOLOGICAL ACTIVITY OF ENDOPHYTIC BACTERIA FROM MEDICINAL PLANTS
Authors: Bariya Aastha , Jasani Hitesh , Baraiya Jagruti , Kuvariya Urvashi , Mankad Gira
Published: April 2022

Bacterial endophytes are known to reside inside tissues of plants and can form a variety of different relationships including symbiotic, mutualistic, commensalistic and ammensalism. There has been increasing evidence, that endophytic bacteria can stimulus plant growth significantly by the production of phytohormones analogous to PGPR activity. In the present study, leaf explants of 6 medicinally important plants viz. Abrus precatorius (AP), Aegle marmelos (AM), Aloe barbadensis (AB), Annona squamosal (AS), Azadirachta indica (AI) and Oscimum sanctum (OS) were used for isolation and characterization of bacterial endophytes via morphological, biochemical examinations. Total 21 endophytes were isolated on Luria-Bertani (LB) and Nutrient agar isolation medium. Isolates were further screened for the enzymatic activity (amylase, protease, cellulase and lipase), and antifungal potential against plant fungal pathogen Aspergillus niger. Endophytic bacteria isolates from Aegle marmelos, Aloe barbadensis, and Azadirachta indica showed maximum amylase, protease, cellulase, and lipase activities in addition to antifungal activities. The screened endophytic isolates will be useful as a possible source of novel bioactive metabolites and potential biopesticides and biofertilizers.
FORMULATION AND CHARACTERIZATION OF ACECLOFENAC LOADED STARCH MICROSPHERE
Authors: Yadav Rajni , Drammeh Isatou , Galgano Joseph
Published: April 2022

Microspheres are a new category of novel drug delivery system which targets to increase the bioavailability and is formulated expediently to obtain prolonged or controlled drug delivery system in the body. Aceclofenac; a non steroidal anti inflammatory drug, is used to treat hurting rheumatic conditions such as osteoarthritis, rheumatoid arthritis and alkylosing spondylitis. It eases pain and reduces inflammation at various sites. Aceclofenac acts by blocking the effect of chemical mediators called cyclo-oxygenase (COX) enzymes which are released at inflamed regions. The aim of this research was to formulate Aceclofenac loaded starch microspheres and evaluate its in vitro properties to enhance the bioavailability of aceclofenac tablet. Aceclofenac loaded starch microspheres were prepared using emulsion cross linking method. Aceclofenac microspheres loaded with starch polymer were characterized, evaluated and it was found to influence all the parameters. The microspheres prepared showed great entrapment efficiency. In vitro release of all prepared polymeric formulations was quite good.
BIODEGRADATION OF PESTICIDES THROUGH METAGENOMIC APPROACHES
Authors: Sundaram S Karthik , Taj N. Afreen , Menaka R , Ajitha C
Published: April 2022

The idea behind the work is to check for the residence of pesticide degrading genes in plasmids and to transform them on an expression vector allowing them to degrade the pesticide more efficiently. Seven different commercially used toxic pesticides were used for bioremediation study. Around 20 organisms were first isolated and based on their pesticide tolerance, 11 organisms were further used for analysis. Each of the organisms was first subjected to plasmid curing and confirmed for their ability of pesticide degradation ability on plasmids. From the isolated 6 organisms based on their efficiency, 3 isolates containing plasmids were further chosen. Their plasmids were extracted and transformed to E.coli DHα. Upon subjecting them to agarose gel electrophoresis the result implies the successful transformation of only two plasmid DNA to the host cell. The pesticide degradation rate of the genetically modified strain was found to be higher than that of the wild type adapted strain. Morphometeric and germinating ability of Venia radiata was tested in pesticide contaminated soil and was found to support the growth of the plant.
DEVELOPMENT OF KARANJ OIL AND CASTOR OIL NANOEMULSIONS AND ITS ENCAPSULATION INTO BEADS FOR CONTROLLED RELEASE LARVICIDAL ACTIVITY
Authors: Jadhav Kartiki B , Nagarkar Jayashree M
Published: April 2022

Karanjin and Ricinoleic acid, found in Karanj oil and Castor oil respectively exhibited medicinal and pesticidal properties. Karanj oil and Castor oil has low aqueous solubility, high photo sensitivity which restrict its application for the control of agricultural pests. The present study highlights development of Karanj oil and Castor oil nanoemulsions and its encapsulation into Calcium alginate beads for control release application. The encapsulated beads were characterized by various physicochemical properties such as size, encapsulation efficiency, release kinetics and stability. The beads exhibited a nearly spherical shape and are nonporous in nature. FTIR spectral studies revealed the absence of chemical interactions between active ingredients and crosslinking agent. The encapsulated Karanj oil and Castor oil nanoemulsions showed the potential for controlled release of Karanjin and Ricinoleic acid. The encapsulated beads of Karanj oil and Castor oil nanoemulsions were tested for larvicidal activity and proved to be effective against variety of mosquito species. The advantages of these biopesticidal formulations appear to be an excellent alternative to conventional pesticides.
MEASUREMENT OF HAEMOCYTES OF GASTROPODS THROUGH AN AUTOMATED IMAGE SCREENING APPROACH BY USING IMAGE PROCESSING TOOL
Authors: Ghosh Arunava , Chatterjee Tapan Kumar
Published: April 2022

The present study was screened to determine the number of total haemocytes and measurement (mean radius) of haemocytes, cytoplasm, and nuclei in an image of gastropod haemocytes (Leishman stained) by using Cell Profiler (CP) version 2.1.0; an image analysis tool. The results of primary (nucleus), secondary (haemocyte) and tertiary (cytoplasm) object data, shown that marking of nuclei, haemocytes and cytoplasm by outline and total accepted objects were obtained 23 nos. in the studied image. The area shape of objects especially haemocytes, cytoplasm, and nuclei (arbitrary unit) in an image were also obtained. In conclusion, this study helps to easily screen the total nos. of haemocytes and area (mean radius) measurement of haemocytes, cytoplasm, and nuclei in the image.
VALIDATED HPTLC METHOD FOR SIMULTANEOUS QUANTIFICATION OF GYMNEMAGENIN AND GALLIC ACID IN HERBAL DOSAGE FORM
Authors: Potawale Rani , Parker Hiba , Karwande Amit
Published: April 2022

The research work was carried out to develop and validate new, rapid, precise and robust high performance thin layer chromatographic method for concurrent quantitative determination of gymnemagenin and gallic acid in selected herbal formulation with densitometric detection. Separation was attained on Merck aluminium HPTLC plates precoated with silica gel 60 F254. The solvent system which is optimaized contained toluene: ethyl acetate: methanol: acetic acid: formic acid (10.4: 4: 4: 0.4: 0.3, v/v/v/v). Developed plates were derivatized by 5% sulphuric acid reagent followed by heating at 110°C for 4 min in a preheated oven followed by scanning at 456 nm in reflectance-absorbance mode. The Rf (Retention factor) was found to be 0.58±0.02, for gymnemagenin and 0.41±0.02, for gallic acid. Results were found to be linear over a range of 200-1000 ng band-1 and 80-240 ng band-1 for gymnemagenin and gallic acid respectively. The proposed HPTLC method was validated according to ICH Q2 (R1) guideline. The proposed HPTLC method can be applied for quality-control testings to quantitative analysis of gymnemagenin and gallic acid simultaneously in selected marketed formulation.
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF ACECLOFENAC BY DIRECT COMPRESSION METHOD
Authors: Ponnaganti Hyma , Anke Kaveri
Published: April 2022

Nowadays, Oro dispersible tablets are gaining much importance because it is easily approachable and due to its patient compliance. In this study, Formulation and evaluation of one such tablets of Aceclofenac by direct compression method using super disintegrants like Cross carmellose sodium (CCS) was performed.

Due to low water soluble property of aceclofenac, it has poor dissolution and bioavailability. In order to minimize this property OTD’s are prepared. ODT’s were prepared by direct compression method using super disintegrant i.e Cross Carmellose Sodium (CCS) in different concentrations. The prepared powder blend was subjected to various evaluation studies like pre compression parameters like angle of repose, tapped density, and bulk density. Post compression parameters like weight variation, hardness, friability, drug content, wetting time, disintegration and dissolution studies were performed. The drug excipients compatibility was verified by FTIR.

The precompression evaluation studies showed that the prepared powder blend has good flow property. The hardness and friability revealed that it has good mechanical strength with acceptable disintegration time. The optimized formulation indicated good in vitro drug dissolution profile with maximum drug being released at all the time intervals indicates an ideal profile for the development of ODT’s. The results of pre compression studies and post compression along with FTIR are presented.
A COMPREHENSIVE ELECTRONIC, VIBRATIONAL, NATURAL BOND ORBITAL AND REACTIVITY DESCRIPTOR ANALYSIS OF PHARMACOLOGICALLY IMPORTANT MOLECULE MIGALASTAT: A THEORETICAL STUDY
Authors: Khare Abhishek , Narayan Vijay , Singh Ashok Kumar , Kumar Amarendra
Published: April 2022

Migalastat (Galafold) is a pharmacological chaperone indicated for the long term treatment for fabry disease a rare genetic disorder in adults. Quantum chemical calculations of energy, geometrical shape and vibrational wavenumbers of Migalastat have been accomplished by the usage of DFT method. The specific exploration of the infrared spectra of the compound underneath have a look at is centered on potential energy distribution (PED). Dipole moment, polarizability and first order static hyperpolarizability calculation using DFT/B3LYP/6-311G(d,p) level of theory outlined the nonlinear optical behavior of the underlying molecule. The frontier molecular orbitals and molecular electrostatic potential map were additionally given to clarify the molecular characteristics of the compound. To show the chemical activity of the chemical compound, reactivity descriptors and thermodynamic properties were also calculated utilizing 6-311G(d,p) basis set. Electron density distribution on atoms and bonds of given molecule was interpreted by its complete NBO analysis.
ASSESSMENT OF MORPHOLOGICAL CHANGES AMONG WHEAT AND ASSOCIATEDWEEDS UNDER HIGH CARBON DI-OXIDE ENVIRONMENT
Authors: Paraste Kamlesh Singh , Kumar Bhumesh , Sandhu S S
Published: April 2022

Climate change and rising CO2 levels as well as weed control is disrupted in both natural and traditional biological ways. The effectiveness of bio-control agents will be compromised as a result of this CO2 -induced morphological, phenological, and physiological alterations. The present study was conducted for the assessment of the effects of elevated CO2 on morphology of wheat crop as well as two commonly associated weeds Phalaris minor and Avena ludoviciana. The plant height of wheat was found to be increased in wheat under elevated CO2 conditions in comparison to ambient environment at 30 DAS and 60 DAS. However, both of the weed species had opposite effect of elevated environment in terms of plant height trait. While taking observation on mean numbers of tillers in wheat crop, it was found to be reduced under elevated environment in comparison to ambient environment. However, both weeds had increment in mean numbers of tillers under elevated CO2 conditions at both 30 DAS and 60 DAS. Results of the present study confirm the effects of elevated CO2 on morphology of crop as well as weed species and indicate the need of research in this field because of alarming situations in the future due to expected increase in CO2 level in the environment.
Analysis of the Determining Factors of Financial Distress (A Case Study at PT. Bank Rakyat Indonesia (Persero)
Authors: Suidarma I Made , Tisya Widyari Ni Wayan , Sudama I Ketut , Arniti Ni Ketut , Marsudiana I Dewa Nyoman , Mahaputra I Dewa Made Rai
Published: April 2022

Economic misery is a circumstance in which the debtor can not satisfy his/her duties to creditors after they fall due. economic distress is the country of the company experiencing economic problems and is threatened with financial ruin. The motive of this study become to decide the impact of Capital Adequacy Ratio (vehicle), Operational costs on working profits (BOPO), Non appearing Loans (NPL), loan to Deposite Ratio (LDR), and go back On belongings (ROA) on monetary distress. This studies changed into conducted at PT (restrained enterprise) bank Rakyat Indonesia (Persero) Tbk. The number of samples is 32 with purposive sampling method. information became gathered using a documentation method, specifically through quarterly monetary document data from 2013-2020 posted at the monetary offerings Authority internet site, www.o.k.go.identity. The effects of speculation testing suggest that the Capital Adequacy Ratio (vehicle) variable has a positive impact on economic misery. Operational fees on running profits (BOPO) have a nice impact on economic distress. Non-appearing loan (NPL) has a terrible effect on financial misery. mortgage to deposit ratio (LDR) has a terrible impact on monetary distress. return on belongings (ROA) has a high quality impact on economic distress. therefore, Capital Adequacy Ratio (automobile), Operational price to operating profits (BOPO), Non acting mortgage (NPL), loan to Deposit Ratio (LDR), and return On assets (ROA) simultaneously affect economic distress.