bluuebunny/crossref_metadata_2025 huggingface dataset:
Superior resolution through multiparameter FWI imaging: A new philosophy in seismic processing and imaging
Authors: McLeman James , Rayment Tom , Burgess Tim , Dancer Karen , Hampson Gary , Pauli Alex
Published: January 2023

Seismic processing and imaging workflows have been refined over many decades to attenuate aspects of the recorded wavefield which would be improperly mapped into the image domain by legacy migration algorithms such as Kirchhoff prestack depth migration. These workflows, which include techniques such as deghosting, designature, demultiple, and regularization, have become increasingly complex and time-consuming due to the sequential fashion in which they must be tested and applied. The single-scattering (primary-only) preprocessed data are then migrated and used in extensive model building workflows, including reflection residual moveout tomography, to refine low-frequency subsurface models. Obtaining optimal results at each stage requires subjective assessment of a wide range of parameter tests. Results can be highly variable, with different decisions resulting in very different outcomes. Such workflows mean that projects may take many months or even years. Full-waveform inversion (FWI) imaging offers an alternative philosophy to this conventional approach. FWI imaging is a least-squares multiscattering algorithm that uses the raw field data (transmitted and reflected arrivals as well as their multiples and ghosts) to determine many different subsurface parameters, including reflectivity. Because this approach uses the full wavefield, the subsurface is sampled more completely during the inversion. Here, we demonstrate the application of a novel multiparameter FWI imaging technique to generate high-resolution amplitude variation with angle reflectivity simultaneously with other model parameters, such as velocity and anisotropy, directly from the raw field data. Given that these results are obtained faster than the conventional workflow with a higher resolution, improved illumination, and reduced noise, we highlight the potential of multiparameter FWI imaging to supersede the conventional workflow.
Inversion-based multistage seismic data processing with physics-driven priors
Authors: Kumar Rajiv , Kamil Yousif , Bilsby Phillip , Narayan Anu , Mahdad Araz , Brouwer Wouter Gerrit , Misbah Amr , Vassallo Massimiliano , Zarkhidze Alexander , Watterson Peter
Published: January 2023

Various aspects of survey design have a profound impact on how noise appears on the coherent signal of interest, thus impacting conventional inversion methods in complex environments. We propose a multistage physics-driven prior-based processing technique that is versatile and can be used in a wide range of inversion-based processing applications such as source separation and/or interpolation for any acquisition environments (e.g., land, marine, and ocean-bottom nodes). The inversion-based multistage approach progressively builds the coherent signal model while eliminating the aliasing, blending, and background noise in a signal-safe manner. To stabilize the inversion process, we include physics-driven priors in the multiple stage process, which enhances the sparsity of the coherent signal in the transform domain. Results using real data from land and ocean-bottom node surveys validate the potential of the proposed approach to produce optimal processing results while dealing with the common geophysical challenges related to different seismic acquisitions.
EcoSeis: A novel acquisition method for optimizing seismic resolution while minimizing environmental footprint
Authors: Naghizadeh Mostafa , Vermeulen Peter , Crook Andrea , Birce Alyson , Ross Stephanie , Stanton Aaron , Rodriguez Maximo , Cookson Warren
Published: January 2023

All exploration and production projects, whether for oil-and-gas, mining, or clean-technology applications, begin with an accurate image of the subsurface. Many technologies have been developed to enable the acquisition of cost-effective seismic data, with high-density land seismic programs becoming commonplace. However, as the industry progresses and the long-term surface footprint associated with these programs becomes better understood, new methods are needed to reduce the environmental impact of seismic data acquisition while maintaining sufficient subsurface resolution for accurate resource development. New acquisition geometries are typically easier to create than test in the field due to the high cost of field acquisition and processing. However, by using existing data acquired in a grid, one can decimate the original data set into multiple geometries and process them. This provides an opportunity to fully test new geometries without the expense of field acquisition. In this paper, we present processing, interpretation, and inversion tests from an existing ultra-high-density oil-sands seismic data set decimated based on ecologically improved program designs. We then measure and compare the results to understand the impact of these geometries on subsurface resolution.
Efficacy of psychosocial interventions for survivors of intimate partner violence: protocol for a systematic review and meta-analysis
Authors: Micklitz Hannah M. , Glass Carla M. , Bengel Jürgen , Sander Lasse B.
Published: January 2023

Survivors of intimate partner violence (IPV) are at risk for serious health consequences, and providing effective psychosocial interventions to support these individuals is a major global health challenge. Previous systematic reviews and meta-analyses in this field do not allow for clear conclusions about the efficacy of these interventions, owing to a narrow focus on specific subpopulations or intervention formats. This protocol presents a systematic review and meta-analysis, which will provide a comprehensive overview of the empirical evidence of various psychosocial interventions for survivors of IPV and investigate their efficacy in improving safety-related, mental health and psychosocial outcomes both overall and within homogeneous subgroups (trial registration: https://osf.io/4gp95). We will systematically search the literature databases PsycInfo, MEDLINE, Embase and CENTRAL. Randomised controlled trials evaluating the efficacy of psychosocial interventions in increasing the safety or mental health of IPV survivors compared with a control group will be eligible. We will extract relevant data from eligible studies and assess study quality using the Cochrane Risk of Bias 2 (RoB 2) tool. We will qualitatively summarise the results and we will calculate weighted effect sizes under random effect model assumption for the primary outcomes IPV, depression and post-traumatic stress disorder. We will perform subgroup analyses to investigate the moderating effects of theoretical basis, delivery mode, intensity and setting of psychosocial interventions. The resultant overview of the current body of evidence for psychosocial interventions for IPV survivors is intended to inform future research and practice.
Machine Learning and Nomogram Prognostic Modeling for 2-Year Head and Neck Cancer–Specific Survival Using Electronic Health Record Data: A Multisite Study
Authors: Kotevski Damian P. , Smee Robert I. , Vajdic Claire M. , Field Matthew
Published: January 2023

PURPOSE

There is limited knowledge of the prediction of 2-year cancer-specific survival (CSS) in the head and neck cancer (HNC) population. The aim of this study is to develop and validate machine learning models and a nomogram for the prediction of 2-year CSS in patients with HNC using real-world data collected by major teaching and tertiary referral hospitals in New South Wales (NSW), Australia.

MATERIALS AND METHODS

Data collected in oncology information systems at multiple NSW Cancer Centres were extracted for 2,953 eligible adults diagnosed between 2000 and 2017 with squamous cell carcinoma of the head and neck. Death data were sourced from the National Death Index using record linkage. Machine learning and Cox regression/nomogram models were developed and internally validated in Python and R, respectively.

RESULTS

Machine learning models demonstrated highest performance (C-index) in the larynx and nasopharynx cohorts (0.82), followed by the oropharynx (0.79) and the hypopharynx and oral cavity cohorts (0.73). In the whole HNC population, C-indexes of 0.79 and 0.70 and Brier scores of 0.10 and 0.27 were reported for the machine learning and nomogram model, respectively. Cox regression analysis identified age, T and N classification, and time-corrected biologic equivalent dose in two gray fractions as independent prognostic factors for 2-year CSS. N classification was the most important feature used for prediction in the machine learning model followed by age.

CONCLUSION

Machine learning and nomogram analysis predicted 2-year CSS with high performance using routinely collected and complete clinical information extracted from oncology information systems. These models function as visual decision-making tools to guide radiotherapy treatment decisions and provide insight into the prediction of survival outcomes in patients with HNC.
On the Hermitian momentum of Wigner-Dunkl quantum mechanics
Authors: Chung Won Sang , Junker Georg , Dong Shi-Hai , Hassanabadi Hassan
Published: January 2023

In this paper the Hermitian momentum operator on the usual Hilbert space is constructed for the Wigner-Dunkl quantum mechanics utilizing a symmetric Dunkl derivative. The inverse of the derivative is shown to exhibit different realization on the subspaces of even and odd functions. The continuity conditions at finite discontinuities of symmetric potential is investigated. As an example, the finite symmetric square well is discussed in detail.
Model studies on motion of respiratory droplets driven through a face mask
Authors: Karmakar Rahul , Ghosal Aishani , Chakrabarti J.
Published: January 2023

Face masks are used to intercept respiratory droplets to prevent spreading of air-borne diseases. Designing face masks with better efficiency needs microscopic understanding on how respiratory droplets move through a mask. Here we study a simple model on the interception of droplets by a face mask. The mask is treated as a polymeric network in an asymmetric confinement, while the droplet is taken as a micrometer-sized tracer colloidal particle, subject to driving force that mimics the breathing. We study numerically, using the Langevin dynamics, the tracer particle permeation through the polymeric network. We show that the permeation is an activated process following an Arrhenius dependence on temperature. The potential energy profile responsible for the activation process increases with tracer size, tracer bead interaction, network rigidity and decreases with the driving force and confinement length. A deeper energy barrier led to better efficiency to intercept the tracer particles of a given size in the presence of driving force at room temperature. Our studies may help to design masks with better efficiency.
Mechanisms of eukaryotic transcription termination at a glance
Authors: Xie Juanjuan , Libri Domenico , Porrua Odil
Published: January 2023

Transcription termination is the final step of a transcription cycle, which induces the release of the transcript at the termination site and allows the recycling of the polymerase for the next round of transcription. Timely transcription termination is critical for avoiding interferences between neighbouring transcription units as well as conflicts between transcribing RNA polymerases (RNAPs) and other DNA-associated processes, such as replication or DNA repair. Understanding the mechanisms by which the very stable transcription elongation complex is dismantled is essential for appreciating how physiological gene expression is maintained and also how concurrent processes that occur synchronously on the DNA are coordinated. Although the strategies employed by the different classes of eukaryotic RNAPs are traditionally considered to be different, novel findings point to interesting commonalities. In this Cell Science at a Glance and the accompanying poster, we review the current understanding about the mechanisms of transcription termination by the three eukaryotic RNAPs.
Fredrickson on Flourishing through Positive Emotions and Aristotle’s Eudaimonia
Authors: Valenzuela Pia
Published: January 2023

Is it possible to be happy without virtues? At least for the kind of enduring human happiness Aristotle bears, virtues are required (NE, I). In addition to virtues, some prosperity is necessary for flourishing, like having friends and minimal external goods. Nowadays, we witness different approaches to happiness – well-being – focusing on mental states – i. e. affective – usually without reference to moral issues, concretely moral dispositions, or virtues. At the crossroads of Philosophy and Psychology, the present article discusses the connection of happiness – well-being – and affective states by presenting Fredrickson’s theory of positive emotions, which has been criticised as approaching only hedonic well-being and therefore overlooking its eudaimonic aspects. In her approach, there is no reference to the good life connected to the human good, as in Aristotle’s ethics. However, there is instead an understanding of becoming a benevolent, a better person as a necessary human aspiration.
Stoic Cognitive Theories and Contemporary Neuropsychological Treatments
Authors: Kormas Panagiotis
Published: January 2023

During the Hellenistic period the value of philosophical systems was to be judged by a meta-philosophical criterion, i.e., by their ability to lead practitioners towards the pursuit of good or happiness, albeit treating pain and sorrow, since all human beings are supposed to be able to reach the state of happiness via their own efforts. By emphasizing the role of thoughts or judgments, Stoics placed cognition in the intermediate phase between an event and the reaction that somebody has due to the event, rendering it both the cause and the cure of emotional disorders. This viewpoint is also fundamental in modern cognitive psychotherapy, although the parallelism goes beyond theory to the practical character in both approaches. Rational and non-rational aspects of human psychology cannot be isolated from each other, allowing thus adults to actively engage in their moral development by altering their beliefs. In this frame, cognitive distancing, the practice of awareness, attention to the present moment, and the Socratic dialogue become valuable tools in structuring emotional self-regulation.
Η χρήση της μεθόδου της αναστοχαστικής ομάδας από το χώρο της Συστημικής Οικογενειακής Θεραπείας στην Εκπαίδευση Ενηλίκων: απόψεις ειδικών ψυχικής υγείας – εκπαιδευτών/τριών ενηλίκων
Authors: Dedousi Niki
Published: January 2023

Σκοπός της παρούσας έρευνας είναι η επίτευξη της σύνδεσης  των επιστημονικών περιοχών της Ψυχολογίας και της Εκπαίδευσης Ενηλίκων, επιχειρώντας τη διερεύνηση των απόψεων ειδικών ψυχικής υγείας – εκπαιδευτών/τριών ενηλίκων για τη χρήσης της μεθόδου της αναστοχαστικής ομάδας από το χώρο της Συστημικής Οικογενειακής Θεραπείας, στην Εκπαίδευση Ενηλίκων ως ένα εφαλτήριο για την προαγωγή της μετασχηματίζουσας μάθησης. Τα ερευνητικά ερωτήματα αφορούν τη διερεύνηση της δυνατότητας της αναστοχαστικής ομάδας να λειτουργήσει ως εργαλείο μετασχηματισμού, την ανάδειξη των προϋποθέσεων για την ανάπτυξη του κριτικού στοχασμού κατά τη χρήση της αναστοχαστικής ομάδας καθώς και τα πιθανά εμπόδια που μπορεί να αναδυθούν σε αυτή τη διαδικασία. Για το σκοπό αυτό χρησιμοποιήθηκε η ποιοτική μεθοδολογική προσέγγιση, διεξήχθησαν ημι-δομημένες συνεντεύξεις σε εννέα ειδικοί ψυχικής υγείας, οι οποίες έχουν εκπαιδευτεί και στην Εκπαίδευση Ενηλίκων και τα δεδομένα τα οποία εξήχθησαν αναλύθηκαν με τη μέθοδο της θεματικής ανάλυσης. Τα σημαντικότερα συμπεράσματα τα οποία προέκυψαν σχετίζονταν αρχικά με τις παραμέτρους της αναστοχαστικής ομάδας που μπορούν να ενισχύσουν τη μετασχηματιστική της λειτουργία, όπως η πολυφωνία, η απόσταση και το κλίμα που δημιουργείται μέσα στην ομάδα. Επιπλέον, αναδείχθηκε η αναγκαιότητα του να προηγηθεί εκπαίδευση των ατόμων που θα συμμετέχουν στη διαδικασία και η αξιοποίηση της αναστοχαστικής ομάδας σε αντικείμενα ανθρωπιστικών επιστημών ή σε συναντήσεις που αφορούν την προσωπική ανάπτυξη. Μερικά από τα εμπόδια που οι συμμετέχουσες ανέφεραν ότι μπορεί να ανακύψουν ήταν η δυσκολία που σχετίζεται με την αναγκαία έκθεση των ατόμων κατά τη συμμετοχή τους στην αναστοχαστική ομάδα, την ενεργοποίηση μηχανισμών άμυνας καθώς και την απροθυμία του φορέα. Τέλος, υπογραμμίστηκε από την πλειονότητα η σημαντικότητα του ρόλου του/της εκπαιδευτή/τριας ενηλίκων για την έκβαση της χρήσης της μεθόδου της αναστοχαστικής ομάδας στην Εκπαίδευση Ενηλίκων.
Mental health interventions targeting children and young people: A mapping review of interventions, follow-up, and evidence gaps
Authors: Dahlgren Astrid , Borren Ingrid , Axelsdottir Brynhildur , Elvsåshagen Mari , Nilsen Karianne Hammerstrøm
Published: January 2023

Background: Young people with mental illness should be offered evidence-based treatments. In 2018, we developed a national evidence portal in Norway providing mental health professionals and others with living evidence summaries. This immense work has been an important contribution to mental health care in Norway but is also a rich data source for exploring the characteristics and evidence gaps of the existing research internationally. At the time of this study, eight overviews of systematic reviews (OoOs) had been published. These addressed treatments for attention deficit / hyperactivity disorder (ADHD), anxiety, depression, bipolar disorder, psychosis, obsessive compulsive disorder (OCD), self-harm and trauma/ post-traumatic stress disorder. The objective of this study was to do a secondary analysis of this evidence to describe the state-of-the art in this field, and to map:

treatments evaluated for each patient group and the longest time of follow-up

treatment comparisons evaluated for more than one patient group

Methods: We performed a mapping review of the eight OoOs. Data extraction was performed by one author and double-checked by another. All data was entered into Excel. Findings were visualized in descriptive tables and using Sunburst-diagrams. We used statistical thresholds to determine the size of effect and report the associated certainty.

Results: We identified 200 treatment comparisons including a wide variety of interventions. Some mental illnesses are treated mostly with pharmacological or combination therapies and others solely with psychological or psychosocial treatments or with more diversity. The evidence supporting most treatments is of low to very low certainty. Ten percent of the comparisons included follow-up assessments beyond 12 months. Cognitive behavioural therapy, dialectic behavioural therapy, physical activity and mindfulness interventions were effective across populations.

Conclusions: The evidence supporting treatment of mental illness in young people has important limitations. Future research efforts should address these evidence gaps.
Degree of organ damage and inflammatory markers in sepsis mice models inducted by various doses of lipopolysaccharides
Authors: - Arifin , Purwanto Bambang , Indarto Dono , Wasita Brian , Sumanjar Tatar , Poncorini Eti , - Soetrisno
Published: January 2023

Background: Sepsis is a life-threatening disease, and animal models of sepsis are minimal. This study aims to find the optimal dose to make a sepsis mouse model by examining the presence of target organ damage.

Methods: This study used 30 mice divided into four groups. The control group injected 0.5 cc NaCl 0.9% intraperitoneally (i.p.). Group A was injected with lipopolysaccharides (LPS) 0.25 mg/kg B.W. i.p. given on the first and second day, group B was injected with LPS 0.3 mg/kg B.W. i.p. given on the first and second days, and group C was injected by LPS 0.3 mg/kg B.W. single dose i.p. Each group was terminated on the third, fourth, and fifth days.

Results: NF-κB, C-reactive protein (CRP), alanine aminotransferase (ALT), NF-κB examinations, and tumor necrosis factor-α (TNF-α) in all treatment groups increased when compared with the control. The highest degree of histopathological features of the kidneys and liver and the results of immunohistochemistry examinations on the liver and kidneys were shown in group C.

Conclusions: Inflammatory markers (CRP, TNF-α, NF-κB, and expression of NF-κB in liver and kidneys) and characteristics of organ damage (ALT, liver, and kidneys histopathology scores) increase on day 3. The highest increase was in the group administered with LPS 0.3 mg/kg B.W. single dose.
Practice and knowledge of dietary supplement consumption among Indonesian adults post-delta wave of the COVID-19 pandemic
Authors: d'Arqom Annette , Nasution Mhd Zamal , Kadir Sharifah Zamiah Syed Abdul , Yusof Junaidah , Govindaraju Kayatri
Published: January 2023

Background: Increasing dietary supplement (DS) consumption was observed during the COVID-19 pandemic, including during the post-Delta wave period. This study aimed to measure the practice of DS consumption and respondents’ knowledge of DS.

Methods: An internet-based survey was distributed from October-December 2021 and obtained 541 valid and completed responses. Descriptive analysis was performed to present the practice of DS consumption, including frequency, duration, aim, preferable dosage form etc. Level of knowledge on DS principles, side effects and regulation were also measured. Inferential analyses were conducted to determine the predictors of the respondents’ DS practice and level of knowledge.

Results: Data from 541 valid responses showed that 77.63% of respondents consumed DS in the last 3 months, with only 59.52% reporting also consuming DS before the COVID-19 pandemic. One half of the respondents had good knowledge about DS; however, some knowledge regarding side effects and possible drug-supplement interaction needed improvement. Their DS consumption practice was affected by their economic status and history of contracting COVID-19. Nevertheless, the level of knowledge was not affected by the sociodemographic factors and DS supplement experience.

Conclusions: Taken together, the practice of self-consumption of DS in Indonesia is increasing; hence, knowledge of DS is necessary to avoid detrimental effects that might occur in the future. Increasing access to information on better labelling and educating consumers about DS are important actions to consider.
Case Report: Right atrial organized thrombus three years after tricuspid annuloplasty
Authors: Abbass Mohannad , Mariani Silvia , Musa Sami , Erba Nicoletta , Masini Franco , Lentini Salvatore
Published: January 2023

Background: Occurrence of right atrial masses, especially in patients with history of cardiac surgery, is rare. Differential diagnosis between malignant and non-malignant aetiologies might be cumbersome, and surgery is often required to prevent complications or disease evolution.

Case: We report the case of a 16-year-old girl from a rural area of Sudan, who underwent surgery for a modified De Vega’s tricuspid annuloplasty, and mitral and aortic valve replacement with mechanical prostheses. The patient was on regular follow-up but demonstrated a poor compliance to anticoagulation therapy with a time in therapeutic range between 52% and 20%. She remained asymptomatic, but a right atrial mass was diagnosed by transthoracic echocardiography during a follow-up visit 41 months after the first operation. Surgical removal of the mass revealed an organized thrombus arising from the point where the Prolene stitches for the tricuspid annuloplasty were previously passed. The patient recovered from surgery, was discharged home on post-operative day 10 and the first follow-up visit at 30 days after discharge confirmed a good clinical status and a normal transthoracic echocardiography (TTE).

Conclusions: This case report describes the diagnostic and therapeutic work-out of a thrombus formation on the suture lines of a tricuspid annuloplasty. Moreover, it highlights the importance of a strict and long follow-up after valvular surgery and of the adherence to anticoagulation therapy, especially for patients living in rural areas of developing countries.
Industry 4.0 technologies as enablers of sustainability risk management
Authors: Ocicka Barbara , Rogowski Waldemar , Turek Jolanta
Published: January 2023

Motivation: Companies operate in a volatile, uncertain, complex, and ambiguous (VUCA) business environment, as evidenced by massive collapses in commodity prices, acts of terrorism, cyber security threats, natural disasters, technological failures, and pandemics. Numerous reports indicate that the top risks with the highest probability of occurrence in the next decade include extreme weather events, failure of climate protection measures, and man-made environmental damage (The Global Risk Report 2021 of the World Economic Forum, The World Business Council for Sustainable Development report and many others). The UN Sustainable Development Goals (SDGs) cover the above challenges and define the agenda for solving them to 2030. The intensification of environmental and social risks reinforces the need to deepen research and explore new ways of managing sustainability risks (SRs). At the same time, businesses are undergoing the technology transformation (Industry 4.0) accelerated by the COVID-19 pandemic. It became necessary to shift some investment to this business area, which also needs to be supported by additional capital. The technology-driven transformation can significantly support companies in managing SRs.
Aim: The aim of the study is to diagnose the importance of investments in Industry 4.0 technologies (T4.0) as potential enablers supporting sustainability risk management from the perspective of supply chains.
Results: SRs represent one of the critical risk areas of the 21st century. Despite the well-recognized potential of the T4.0 implementation for sustainable supply chain management, the research studies concentrated on their potential role within SR management in international supply chains are limited and fragmented. The diagnosis of the growing importance of T4.0 supporting risk management at strategic and operational levels of business activities implies the recommendation to integrate their use in this area into the technological transformation, and then consistently into planning and financing of development and implementation projects. Companies may attempt to address these challenges through Environmental, Social, and Governance (ESG) initiatives.
Ovarian sclerosing stromal tumor - benign neoplasm of the young. A case study with literature review
Authors: Grzybowski Jakub , Piętak Patrycja , Merkisz Konrad , Nemeczek Sylwia , Marciniak Agnieszka , Walczak Klaudia , Jaskuła Karolina , Orłowski Władysław , Zdun Sylwia , Grzywna Natalia , Walczak Patrycja
Published: January 2023

Sclerosing stromal tumor (SST), located in the ovary, is a very rare disease entity. To date, only a few hundred cases of ovarian SST have been confirmed worldwide. Preoperative diagnosis of stromal tumor is difficult, as clinically and radiologically it resembles other types of ovarian tumors. These tumors present nonspecific symptoms, with irregular menstrual bleeding, lower abdominal pain and palpable pelvic lesions being the most common. Differentiation and diagnosis is possible only thorough histopathological examination and immunophenotyping. In the present study, we presented a case report of a young, 20-year-old patient with an oligosymptomatic  ovarian stromal tumor. We compared and summarized the diagnostic and therapeutic process, as well as the tumor immunophenotypes, with recent cases reported in the literature.
ZARYS DZIAŁALNOŚCI KOMISJI SOBOROWEJ/ KOMISJI DO SPRAW REALIZACJI UCHWAŁ SOBORU WATYKAŃSKIEGO II EPISKOPATU POLSKI W LATACH 1959–1977
Authors: Białkowski Michał
Published: January 2023

Artykuł jest pierwszym w polskiej historiografii kościelnej opisem działalności Komisji Soborowej Komisji do Spraw Realizacji Uchwał Soboru Watykańskiego II Episkopatu Polski w latach 1959–1977. W analizowanym okresie przewodniczył jej abp Antoni Baraniak. Znaczący wkład w jej prace wnieśli: Bolesław Kominek i Karol Wojtyła. Gremium to było głównym organem odpowiedzialnym za wdrażanie uchwał Soboru Watykańskiego II i realizację jego recepcji w Kościele katolickim w Polsce.
PATRZĄC DIABŁU W OCZY: TOTALITARYZM I HUMANITARNO-PERSONALISTYCZNA KONCEPCJA ŻYCIA SPOŁECZNO-POLITYCZNEGO KARDYNAŁA STEFANA WYSZYŃSKIEGO
Authors: Ficek Ryszard
Published: January 2023

The key aim of this article is to expose the specificity of the theory of totalitarianism in the context of Cardinal Wyszyński’s humanitarian-personalist concept of socio-political life. Hence, it provides a unique insight into the nature of totalitarian systems, both German Nazi Hitlerism and Communism. Analyses were performed to reinterpret the above systems from the perspective of Christian personalist praxeology, taking into account the fundamental assumptions of the absolutely anti-human and anti-Christian paradigm that not only defined but also legitimized and even authenticated the most terrible and degenerated forms of totalitarian systems of the 20th century. Therefore, it is crucial, especially today, when emerging tendencies often trivialize the criminal nature of that systems and even treat the “totalitarian model” – particularly in the context of Communism – as a “specific historical phenomenon” aimed at resolving many complicated socio-political, cultural, and economic issues.
JÓZEFA TISCHNERA REFLEKSJE O RODZINIE
Authors: Lewicka Monika
Published: January 2023

W artykule podjęta została próba ukazania roli rodziny w myśli Józefa Tischnera z perspektywy pedagogicznej. Kolejno ukazano potrzebę dialogu w rodzinie. Przedstawiono znaczenie rodziny jako źródła miłości i odpowiedzialności. Zaprezentowano wychowanie w rodzinie w ujęciu Józefa Tischnera.
WYBRANE ZAGADNIENIA Z PRACY ADMINISTRACYJNO-PASTERSKIEJ BISKUPA KAZIMIERZA JÓZEFA KOWALSKIEGO W LATACH 1946–1951
Authors: Malinowski Adam
Published: January 2023

Biskup Kazimierz Józef Kowalski przybył do diecezji chełmińskiej w 1946 roku. Przez całe dotychczasowe życie był związany z Kościołem gnieźnieńskim i poznańskim. Przybycie na teren diecezji obcej i pod wieloma aspektami zniszczonej przez działania okupanta niemieckiego mogło rodzić wyzwanie. Biskup Kowalski od początków swojej posługi podjął się odbudowy tego, co zostało zniszczone podczas wojny. Zaczął od reform administracyjnych – ustanawiał nowe parafie, zadbał o obsadę personalną tych miejsc, które wakowały z powodu śmierci bądź wojennej emigracji kapłanów. Dbał o sztukę sakralną (w Episkopacie zasiadał w Komisji ds. Sztuki Sakralnej) – czego wyrazem były liczne zarządzenia i apele. Wygłaszał nauki i homilie z okazji ważnych wydarzeń nie tylko w skali Kościoła diecezjalnego, ale i ogólnopolskiego. Zadbał o pamięć pomordowanych kapłanów, czego symbolicznym aktem był pochówek zmarłego w czasie wojny biskupa pomocniczego Konstantyna Dominika. Pomagał wiernym poranionym przez wojnę wrócić do praktyk duchowych i duszpasterskich – w tych kwestiach odznaczał się wyrozumiałością i delikatnością. Jego życie było podporządkowane Kościołowi, czego dowiódł, wybitnie zarządzając diecezją w pierwszych (niewątpliwie najtrudniejszych) latach jej funkcjonowania po wojnie.
SPIRIT-UAL WORD-FOR-WORDNESS: THE RELATIONSHIP BETWEEN PNEUMATOLOGY AND CHRISTOLOGY IN THE LIGHT OF JOSEPH RATZINGER’S / BENEDICT XVI’S THEOLOGY AND TEACHING
Authors: Szymik Jerzy
Published: January 2023

Joseph Ratzinger / Benedict XVI proposes a pneumatology derived from the Trinitarian dogma, strictly linked with Christology and having anthropological, ecclesiological, and pastoral consequences (in the domain of spirituality). All theological subdisciplines remain orthodox and lead to the truth only when interlinked, but pneumatology has a particularly “linking” quality because it concerns the One who is, essentially, communion and unity. The intra-Trinitarian “position” of the Holy Spirit explains the structure of the entire reality (including the human, personal reality, together with faith): what is spiritual makes existence more consistent and unites rather than dualizes or divides it. It unifies by creating a relationship (communion) rather than by negating identity (the earthly, physical, and historical specificity), as some heresies or ideologies would have it. Just like the Spirit always acts in communion with the Incarnate Word, Christian spirituality is always set in the historical form of the Church, and charism is always given within institutional structures. Being close to Christ and humility before the humble God is the source of true spirituality.
Nuevo rumbo en las relaciones laborales de las personas trabajadoras al servicio del hogar familiar.
Authors: Romeral Hernández Josefa
Published: January 2023

El trabajo al servicio del hogar es una de las fuentes de empleo más importantes tanto por el número de trabajadores que ocupa como por su contribución al funcionamiento general de la economía y la vida social. Sin embargo, ha sido una de las formas de trabajo más precarias, peor remuneradas y desprotegidas a lo largo de la historia debido al desprestigio que envuelve el contenido de la actividad, desarrollado fundamentalmente por mujeres en el domicilio del empleador; lo que dificulta su organización como colectivo y el control de las condiciones de trabajo. El reciente Real Decreto-ley 16/2022 para la mejora de las condiciones de trabajo y de Seguridad Social de las personas trabajadoras al servicio del hogar, viene a saldar la deuda histórica con este colectivo, removiendo los preceptos de la normativa laboral que suponen una diferencia de trato carente de justificación objetiva, como son: la protección por desempleo, la exclusión de la Ley de Prevención de Riesgos Laborales, la protección por el Fondo de garantía salarial y la extinción del contrato sin causa, entre otras, para adecuarlas a las exigencias de normativa Europea y el Convenio 189 de la OIT recientemente ratificado por España. Todas ellas, cuestiones objeto de análisis en este estudio junto con las acciones pendientes a futuro.
Drug Breakdown: Celecoxib
Authors: Rees Sharon
Published: January 2023

In this column, Sharon Rees aims to refresh knowledge and interest in some of the commonly used drugs in a series of tweets. This month she is talking about #celecoxib
The Development of a Four-Tier Diagnostic Test Based on Modern Test Theory in Physics Education
Authors: Istiyono Edi , Dwandaru Wipsar Sunu Brams , Fenditasari Kharisma , Ayub Made Rai Suci Shanti Nurani , Saepuzaman Duden
Published: January 2023

Diagnostic tests are generally two or three-tier and based on classical test theory. In this research, the Four-Tier Diagnostic Test (FTDT) was developed based on modern test theory to determine understanding of physics levels: scientific conception (SC), lack of knowledge (LK), misconception (MSC), false negatives (FN), and false positives (FP). The goals of the FTDT are to (a) find FTDT constructs, (b) test the quality of the FTDT, and (c) describe students' conceptual understanding of physics. The development process was conducted in the planning, testing, and measurement phases. The FTDT consists of four-layer multiple-choice with 100 items tested on 700 high school students in Yogyakarta. According to the partial credit models (PCM), the student's responses are in the form of eight categories of polytomous data. The results of the study show that (a) FTDT is built on the aspects of translation, interpretation, extrapolation, and explanation, with each aspect consisting of 25 items with five anchor items; (b) FTDT is valid with an Aiken's V value in the range of 0.85-0.94, and the items fit PCM with Infit Mean Square (INFIT MNSQ) of 0.77-1.30, item difficulty index of 0.12-0.38, and the reliability coefficient of Cronbach's alpha FTDT is 0.9; (c) the percentage of conceptual understanding of physics from large to small is LK type 2 (LK2), FP, LK type 1 (LK1), FN, LK type 3 (LK3), SC, LK type 4 (LK4), and MSC. The percentage sequence of MSC based on the successive material is momentum, Newton's law, particle dynamics, harmonic motion, work, and energy. In addition, failure to understand the concept sequentially is due to Newton's law, particle dynamics, work and energy, momentum, and harmonic motion.
The Possibility of Applying the Social-Emotional Learning Model in Teaching of Primary Teachers: A Vietnamese Case Study
Authors: Huynh Van-Son , Giang Thien-Vu , Nguyen Vinh-Khuong , Nguyen Chung-Hai , Bui Hong-Quan
Published: January 2023

Although the social-emotional learning model (SEL) has been researched in Vietnam for many years, studies on teachers' SEL-based teaching competence have not been the focus. This study explored the possibility of applying the SEL model to the teaching of Vietnamese primary school teachers. Our case study of 50 teachers who participated in previous SEL projects highlights three factors that prevented successful SEL application in Vietnamese schools, including (a) confusion about the SEL-based teaching perspective, (b) traditional teaching methods, (c) limited training in social-emotional skills, and mental health policies for primary school teachers. The findings have broadened and deepened our understanding of the possibility of successful application of the SEL model in the classroom, which would depend on SEL-based professional supervision, consistency in SEL-based teaching methods and SEL practice guides/manuals, and promotion or adaptation of policies for SEL-based practice and application in schools.
Alpha and Theta EEG Rhythms Activity Reveal Deep Changes in Resting Brain State in Subjects with Prodromal Alzheimer's Disease
Authors: Moretti D.V. , Prestia A. , Binetti G. , Zanetti O. , Frisoni G.B.
Published: January 2023

The increase of EEG alpha3/alpha2 frequency power ratio has been associated with AD-converters subjects with mild cognitive impairment (MCI) as well as a reduction in the regional cerebral blood flow (rCBF).
In this study, the association between alpha3/alpha2 frequency power ratio with rCBF changes in subjects with MCI was evaluated.
The alpha3/alpha2 frequency power ratio was computed in 27 subjects with MCI. Two groups were obtained according to the median values of alpha3/alpha2, at a cut-off of 1.17. In the groups so obtained, the correlation between brain perfusion and EEG markers were detected.
In the MCI group with the alpha3/alpha2 frequency power ratio above 1,17 as compared to the group with alpha3/alpha2 frequency power ratio below 1.17 there was: 1) a constant trend to lower rCBF values; 2) smaller hippocampal volumes; 3) higher theta frequency power.
The higher EEG alpha3 /alpha2 frequency power ratio individuates two different group of MCI subjects. A complex interplay between alpha and theta rhythms activity MCI patients is suggested in patients with prodromal Alzheimer's disease.
Heberden´s Nodes in Women Complicated with Tophi Gout
Authors: Vachtenheim Julius
Published: January 2023

Gout is currently a very widespread metabolic joint disease. In the course of the long history of gout treatment since Hippocrates the opinion of this disease have changed many times, especially concerning frequency, cause and therapy. Now we are far from thinking that gout occurs only in the “upper class” male population. This article comments the occurens of gout tophi in atypical locations in females, which occur not only on the typical sites, namely 1st metatarsal joint of the foot thumb as a typical for the primary gout. It is also necesary to note that gout currently occurs in females more often than before, including also the tophi gout, which appears not only as primary but also as a secondary gout. It occurs in patiens with chronic renal failure, on the basis of long-term renal disease with longlasting hyperuricaemia. The crystals may settle in a remote damaged hand joint at sites of long lasting osteo-arthritis. This especially applies to Heberden´s nodes (distal interphalangeal joint), mainly on the index fingers. Rarely also can applies to the proximal interphalangeal joint (Bouchard´s nodes). Similar observation has not been found so far in the literature.
Corpora Amylacea in Aging Brain and Age-Related Brain Disorders
Authors: Pirici Daniel , Margaritescu Claudiu
Published: January 2023

Corpora amylacea (CA) are glycoprotein-based hyaline-like bodies that accumulate in normal aging brain, and to an even greater extent, in the brains of patients suffering from a variety of neurodegenerative disorders.
Although many of the histochemical, tinctorial and structural properties of CAs have been described for more than a century and a half since their discovery, their pathogenic mechanisms, their subcellular origins and their functions are still debated. Two main theories have been advanced to explain the formation of CA, respectively the vascular and the metabolic theories, although pathogenically both mechanisms can be involved. The exact cellular source of CA in the nervous system is still under debate, although both a neuronal and glial origin has been suggested due to the presence of cell specific proteins. CAs contain around 90% glucose polymers (polyglucosan or polysaccharides), 3% phosphates and 5% proteins, most of them being aging or stress-related proteins. Ultrastructurally, CAs were described as masses of randomly oriented short linear electron-dense areas, situated in the cytoplasm of fibrous astrocytes, mainly in their distal processes. In transmission light microscopy they appear as circular bodies ranging from less than 2 µm to about 20 µm in diameter, with smooth surface or ragged appearance that typically have a concentric laminated or target-like patterns, with the cores staining rather more densely than the periphery.
Besides their presence in aging brain, in many neurodegenerative disorders some similar structures called polyglicosan bodies, are morphologically indistinguishable from normal CAs, and were described in: Anderson’s disease, adult polyglucosan body disease, inflammatory demyelinating polyneuropathy, diabetic neuropathy, and in the neurons of patients with Lafora progressive myoclonus epilepsy. The differential diagnosis may include all the neuropathological diseases characterized by the production of peculiar materials with special morphology in the elderly.
All together, these data come to show that these “enigmatic bodies” are far from being completely understood, thus further investigations are needed to better explain the brain aging and the pathogenesis of different degenerative neurological diseases, and perhaps they could provide novel therapeutic targets to counteract age-related brain disorders.
Simfield: A Computer Simulated Visual Field Test to Screen for Glaucoma
Authors: Hellman Justin B. , Perrone Marie , Al-khersan Hasenin , Altamirano Diego , Farrokh-Siar Lili , Ksiazek Susan
Published: January 2023

Objective: To evaluate the efficacy of a computer simulated visual field test (Simfield) as a screening tool for glaucoma.
Design/Participants/Methods: 36 glaucoma or glaucoma suspect patients (53 eyes) from one ophthalmology clinic between October 2013 and May 2014 used the Simfield program within six months of a reliable performance on a 24-2 SITA standard Humphrey Visual Field Analyzer Exam. The exam measured threshold values at the same 54 points as the 24-2 SITA standard software as well as false positives, false negatives, and fixation losses. Two glaucoma specialists and one general ophthalmologist analyzed the Simfield results in masked fashion and determined whether there was evidence of a glaucomatous defect in any of the 4 quadrants of each field. These results were compared to the corresponding HFA tests to determine sensitivity and specificity.
Results: The sensitivity of Simfield ranged from 51-76% and the specificity was 67-88%. In a sub analysis that eliminated mild defects, defined as defects in a field with mean deviation < 7.0, sensitivity improved to 75-91% and specificity was 69-91%. The average false positive rate was 5.2%, the average false negative rate was 3.7%, and the average fixation loss rate was 27.7%.
Conclusions: Simfield is an effective test for identifying moderate to severe glaucomatous visual field loss and can be accessed from any home computer. While the cost to detect glaucoma in one patient using current screening methods is estimated at $1000, Simfield can be used for free anywhere that a computer is available.
Effect of Cationic Antimicrobial Protein CAP37 on Cytokine Profile during Corneal Wound Healing
Authors: Kasus-Jacobi Anne , Griffith Gina L. , Lerner Megan , Pereira H. Anne
Published: January 2023

The cationic antimicrobial protein of 37 kDa (CAP37) mediates proliferation, migration, and adhesion of human corneal epithelial cells and promotes corneal re-epithelialization in mouse. The purpose of this study was to investigate the cytokine profile following abrasion of the corneal epithelium, and to identify the cytokines modulated by topical treatment with CAP37 to determine the mechanism by which CAP37 contributes to the recruitment of inflammatory cells and healing of the cornea.
The corneal epithelium in mouse eyes was removed and wounds were treated with a saline vehicle or human recombinant CAP37. Wounds were visualized with fluoresce in staining at 0, 16, 24 and 48 h. Mouse corneas were excised at 0, 6, 16, 24 and 48 h post corneal abrasion. The excised corneas were analyzed by immunohistochemistry for re-epithelialization and infiltration of inflammatory cells while the expression profiles of thirty-two cytokines were investigated by multiplex analysis.
Results corroborating previous studies showed accelerated wound closure in corneas treated with CAP37 compared to those treated with the saline vehicle. Immunohistochemistry revealed less neutrophil infiltration in CAP37-treated corneas when compared to controls at 24 h. By 48 h post-wounding, histological analysis revealed more staining for neutrophils than the staining observed in the controls. Modulation of cytokine expression occurred for the majority of the cytokines tested at the time of corneal abrasion, during re-epithelialization, and/or by CAP37 treatment. Cytokines monocyte chemoattractant protein-1 (MCP-1) and regulated on activation, normal T cell expressed and secreted (RANTES) were induced during re-epithelialization, at the early 16 h time point. Interleukin 6 (IL-6), leukemia inhibitory factor (LIF), granulocyte colony-stimulating factor (G-CSF), IL-12p70, macrophage inflammatory protein 1 beta (MIP-1β), and interferon gamma-induced protein 10 (IP-10) were induced at 24 h and unchanged during CAP37 treatment. By contrast, IL-15, monokine induced by gamma interferon (MIG), keratinocyte-derived cytokine (KC), tumor necrosis factor alpha (TNF-α), MIP-1α, IL-1β, and macrophage colony-stimulating factor (M-CSF) were modulated by CAP37 treatment. In general, CAP37 appeared to decrease pro-inflammatory cytokines at 24 h and increase them at 48 h when compared to the control group.
These data demonstrate that CAP37 modulates the production of cytokines in the cornea and suggest that limiting the number of neutrophils recruited during the early inflammatory phase may support corneal re-epithelialization.