bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis lingüístico-semiótico : la valorización utópica en el spot publicitario
Authors: Pellicer García Lidia
Published: July 2020

La creación de la personalidad de la marca atiende a unos valores semántico-discursivos, siendo uno de ellos el valor utópico mediante el cual el sujeto realiza su propia identidad conjugándose con su objeto de valor.Branding personality creation has a semantics-discursives values. One of them is the utopic value with a subject does his own identity with his value object.
Semiótica de la narración judicial : un caso de violencia de género
Authors: Valverde Velasco Alicia , Ridao Rodrigo Susana
Published: July 2020

En el marco de la investigación interdisciplinar, la combinación de los principios teóricos de la narratología y la lingüística forense ofrece la posibilidad de llegar a un conocimiento más preciso en el análisis del discurso de un juicio de violencia de género.In the framework of interdisciplinary research, combining theoretical principles of Narratology and Forensic Linguistics offers the possibility to reach a more precise discourse analysis of a trial of domestic violence.
Prominence matching in english songs : a historical perspective
Authors: Proto Teresa
Published: July 2020

La poesía métrica es la fuente primaria de evidencia lingüística para la reconstrucción del sistema de acentuación de una lengua muerta, y en particular la métrica que controla la coincidencia o ajuste entre acento lingüístico y posiciones fuertes. para el inglés medio, la distribución del acento léxico a través de los esquemas débil/fuerte del pentámetro yámbico, desde chaucer hasta shakespeare, ha ofrecido información importante para el análisis lingüístico. además de la poesía hablada, las canciones proveen otro tipo de poesía métrica presente en este periodo que, sin embargo, aún no ha sido explotado como fuente de evidencia métrica o lingüística. el presente trabajo intenta contribuir a llenar este vacío a través del estudio diacrónico del desajuste prominente.The primary source of linguistic evidence in reconstructing stress systems is provided by metered poetry, particularly by meters that control the matching of the linguistic stress to metrical strong positions. For middle english, the distribution of lexical stress across the weak/strong patterns of iambic pentameter, from chaucer to shakespeare, has provided important clues for linguistic analysis. in addition to spoken poetry, songs provide another type of metered poetry from that period. however, they have not been exploited as a source of metrical or linguistic evidence. the present paper takes a tentative step towards filling this gap, by focusing on a diachronic study of prominence mismatching.
La écfrasis en la obra de Luis Javier Moreno
Authors: Carbajosa Palmero Natalia
Published: July 2020

El presente trabajo analiza la poesía ecfrástica de Luis Javier Moreno dentro del contexto teórico e histórico de la écfrasis, entendida ésta como instrumento semiótico y epistemológico de primer orden y, más concretamente, como elemento mediador entre el poema y la realidad. Desde esta perspectiva múltiple, la naturaleza de la relación verbal-visual que es objeto de la écfrasis adquiere connotaciones heredadas de la época de las vanguardias de principios del siglo XX, claramente relacionadas con la invasión visual de la postmodernidad, lo que se estudiará en relación a los poemas elegidos para el análisis.The present article analyzes the ekphrastic poetry of Luis Javier Moreno within the theoretical and historical context of exphrasis as a primordial semiotic and epistemological source; furthermore, as a mediating element between the poem and reality. From this multiple perspective, the nature of the visual-verbal relationship, which is the concern of ekphrasis, shows connotations brought about by the avant-garde period of the early twentieth century, and clearly related with the current visual invasion of postmodernity. All this will be dealt with in relation to the poems chosen for analysis.
Semiótica del cómic : códigos y convenciones
Authors: Cuñarro Liber , Finol José Enrique
Published: July 2020

El objetivo de este artículo es desarrollar un estudio de las principales convenciones del cómic para abordar el problema lingüístico, icónico y gráfico desde una perspectiva semiótica. El análisis se basa en el estudio de la novela gráfica Civil War (2006), de Marvel. La lectura de una novela gráfica es al mismo tiempo un acto de percepción estética y una persecución intelectual, en ella se entrelazan el régimen artístico (perspectiva, simetría, líneas) y el régimen literario (gramática, trama, sintaxis). Es la existencia de esta gramática y de esta serie de convenciones establecidas las que permiten que el cómic pueda expresar nuestro mundo, mediante la utilización de los códigos lingüísticos e icónicos. Se concluye que mediante la combinación de esta serie de recursos icónicos y lingüísticos, el cómic remite al receptor a un mundo alternativo, utilizando una serie de símbolos que dan lugar a diversas lecturas en cuyo trasfondo existe una cosmovisión que lo orienta en el laberinto de sus vivencias, y haciendo de los personajes de ficción protagonistas arquetípicos de lo que puede o debe ser.The purpose of this article is to develop an investigation of the main conventions in comics: to approach the linguistic and iconic subject from a semiotics perspective. The act of reading a graphic novel is simultaneously an act of aesthetic perception and an intellectual pursuit; in it the artistic world (perspective, symmetry, lines) and the literary world (grammar, plot, and syntax) intertwine. It is the existence of this grammar and this series of established conventions which allows comics to express our world, through the use of iconic and linguistic codes. We conclude that through the combinations of this series of iconic and linguistic resources, comics take the reader to an alternate world using a series of symbols that allow for several different readings, in the subtext of which exist a cosmivision that orients said reader through the labyrinth of his experiences, and makes the fictional characters therein the archetype protagonists of what can or should be.
El lenguaje de los balcones
Authors: Morant Marco Ricard , Martín López Arantxa
Published: July 2020

El presente artículo analiza los usos comunicativos de los balcones, que, además de cumplir una función estética y ambiental, se han convertido, a lo largo del tiempo, en unos soportes de gran riqueza expresiva, especialmente en el paisaje urbano.In the present article, we analize the communicative uses of balconies. Besides their ambiental and esthetic function, balconies have become incredibly expressive supports over time, especially in cities.
Búsquedas femeninas de la identidad : mientras vivimos , de Maruja Torres
Authors: Sánchez Dueñas Blas
Published: July 2020

Este artículo analiza el tratamiento y la construcción de las protagonistas femeninas de la novela Mientras vivimos, de Maruja Torres, a partir del estudio de los conflictos personales y de la búsqueda de identidades entrelazadas que en ella se suceden.This paper examines the treatment and foundations of the female characters in the novel entitled Mientras vivimos, by Maruja Torres, from a study of the personal conflicts and the quest of interwoven identities that can be found in the novel.
Autores y textos teatrales electrónicos (en castellano) del teatro español contemporáneo
Authors: Torre Rodríguez Ricardo de la
Published: July 2020

En el marco de la relación entre teatro y las nuevas tecnologías, una de las líneas de investigación llevadas a cabo en el Centro de Investigación de Semiótica Literaria, Teatral y Nuevas Tecnologías (SELITEN@T: http://www.uned.es/centro-investigacion-SELITEN@T/), el propósito de este artículo es realizar una aproximación a los autores del teatro español contemporáneo y a los textos completos en versión electrónica de sus obras (en castellano), disponibles para la lectura y descarga gratuita desde las páginas en red de los propios autores. Otras páginas seleccionadas completan y proporcionan al investigador o al lector de teatro una visión general de estos autores con los títulos de sus producciones, ordenados alfabéticamente.On the relation between theatre and new technologies, one of the lines of research carried out at the Research Center of Literary and Theatrical Semiotics and New Technologies (SELITEN@T: http://www. uned.es/centro-investigacion-SELITEN@T/), the purpose of this article is to present an approach to the contemporary Spanish playwrights and the full-text electronic version of their plays (in Spanish), available for free reading and downloading from the own authors’ websites. Some other selected sites also complete and provide the research worker or just the play reader with an overview of these authors with the titles of their productions, listed alphabetically.
”No más mostrador” y la comedia moratiniana de la primera mitad del siglo XIX
Authors: Fernández Díaz David Félix
Published: July 2020

"No más mostrador" (1831) de Mariano José de Larra es considerada hoy día por un numeroso sector de la crítica como una comedia moratiniana. Esta clasificación, cuyo inicio data de principios del siglo XX, ha pasado a nuestra historia teatral como una categoría objetiva sin que haya sido cuestionada. Cotejar la crítica decimonónica de esta obra con la elaborada posteriormente revela una disparidad de percepciones que objeta esta validez. Este trabajo presenta un breve panorama sobre qué significa que una comedia sea moratiniana y qué principios debe seguir.Mariano José de Larra’s "No más mostrador" (1831) is nowadays considered by many critics as a moratinian comedy. This classification, which started at the beginning of the XXth century, has been adopted by our history of theater as an objective category without being contested. After comparing No más mostrador’s criticism of the XIXth century with that other criticism created thereafter, it unveils great disparities of perceptions that calls into question its validity. This paper presents a brief panorama of what a moratinian comedy is and which principles should follow.
El coro en la renovación teatral de Cipriano Rivas Cherif
Authors: García-Ramos Merlo Jorge
Published: July 2020

Cipriano Rivas Cherif (1891-1967) representa la dirección de escena renovadora en el teatro español del primer tercio del siglo xx. En sus proyectos teatrales y puestas en escena reincorpora diversos elementos corales (musicales, plásticos, populares, rituales…), mostrándose como un director de teatro total. Para ello tendrá como referencia las modernas corrientes del teatro europeo, que él tanto conocía. La técnica coral coadyuva a conseguir un espectáculo de arte y una mayor comunicación con el público en el teatro. Destacará su colaboración con Valle-Inclán y García Lorca, los dos mayores autores de este teatro coral renovador en España.Cipriano Rivas Cherif (1891-1967) represents the renovating stage direction in the Spanish theater of the first third of the twentieth century. In his theatrical projects and staging he rejoins various choral elements (music, plastic, popular, rituals...), showing himself as a total theater director. For it he will have as reference the currents of modern European theater, which he so much knew. The coral technique contributes to an art show and more communication with the public in the theater. It will be very noteworthy his collaboration with Valle-Inclán and Garcia Lorca, the two major authors of this coral-renovating theater in Spain.
Puestas en escena de obras de dramaturgas en la cartelera de Málaga (2000-2003)
Authors: Jiménez Aguilar Miguel Ángel
Published: July 2020

Este artículo trata sobre las dramaturgas que representaron en los teatros de Málaga de 2000 a 2003. De cada una de ellas ofrece una breve reseña de su vida y su producción dramática, el lugar, la fecha y el ciclo del que formó parte la obra que fue representada, así como un resumen de su contenido. Las autoras aparecen por orden alfabético de apellido en diferentes grupos: españolas, hispanoamericanas y dramaturgas en otras lenguas.This article talks about the women playwrights that appeared in theatres in Málaga from 2000 to 2003. Each one of them offer a brief overview of their lives and their dramatic production, the place, date and cycle which formed part of their presented play as well as a summary of its contents. The women playwrights appear in alphabetical order of surname in different groups; Spanish, Latin-American and women playwrights of other languages.
Algunas muestras de literatura autobiográfica en la prensa española (1975-2010)
Authors: Núñez Díaz Pablo
Published: July 2020

Autobiografías, memorias y escritos diarísticos han experimentado un auge indudable en España desde 1975. Al igual que sucedió con otros géneros en diferentes épocas de nuestra literatura, tanto periódicos como revistas han sido medios fundamentales para su publicación. En este trabajo se lleva a cabo una aproximación a la presencia de dichos textos en la prensa española, desde la fecha mencionada hasta 2010.Autobiographies, memoirs and diaries have undoubtedly undergone an increase in Spain since 1975. As it happened with other genres, at different periods of the history of our literature, authobiografical literature has been very present in periodical publications. In this work there is an effort to approach the importance of these texts in the Spanish press, since the already mentioned date, until 2010.
La ironía en la obra de Juan Rulfo
Authors: Popovic Karic Pol
Published: July 2020

Se analizarán cuatro tipos de ironía —las de Platón, Booth, Hutcheon y Kierkegaard— en la obra de Juan Rulfo. Cada uno ofrece distintos ángulos de observación sobre las tramas y las imágenes plasmadas por el narrador. Observaremos distintas maneras en las que los efectos de la ironía impactan el contenido temático y el aspecto estético de la narrativa de Rulfo.Four types of irony —based on the theories of Plato, Booth, Hutcheon and Kierkegaard— will be used to analyze Juan Rulfo’s work. Each one offers different angles of observation focused on the plot and the images projected by the narrator. We shall observe the ways in which ironic effects impact the thematic content and the esthetic aspect of Rulfo’s narrative.
RESEÑA de: Doménech, Ricardo. El teatro del exilio. Madrid : Cátedra, 2013.
Authors: Abad Francisco
Published: July 2020

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RESEÑA de: Pérez Bowie, José Antonio (ed.). Gonzalo Torrente Ballester y el teatro. Vigo : Universidad de Vigo, 2013.
Authors: García-Abad García M.ª Teresa
Published: July 2020

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RESEÑA de: Trecca, Simone. Silencios, ecos, voces : el proceso de dramatización en las reescrituras para el teatro de Antonio Buero Vallejo. Vigo : Academia del Hispanismo, 2012.
Authors: Fox Manuela
Published: July 2020

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Nestabilna brazgotina kot kronična rana in možnost nastanka Marjolinovega ulkusa
Authors: Emeršič Luka , Stritar Albin
Published: July 2020

Marjolinov ulkus (MU) je redka, vendar izjemno agresivna oblika ulcerativnega ploščatoceličnega karcinoma, ki nastane iz kronične rane, najpogosteje po opeklinski poškodbi. Naš cilj je opozoriti na nevarnost  maligne preobrazbe nestabilne brazgotine kot kronične rane (nastanek Marjolinovega ulkusa) ter možnosti njenega zdravljenja pri nas ter drugod po svetu. V Univerzitetnem kliničnem centru Ljubljana na Kliničnem oddelku za plastično, rekonstrukcijsko, estetsko kirurgijo in opekline smo v obdobju zadnjih 13 let obravnavali 5 bolnikov, operiranih zaradi nestabilne brazgotine, ki se je izkazovala kot kronična rana. Za potrebe članka smo opravili pregled angleške literature na temo ulceracije nestabilne opeklinske brazgotine.

Marjolinov ulkus je epiteliomska sprememba, ki jo je možno preprečiti. Vsaka večja rana, ki se prepusti sekundarnemu celjenju, ima potencial za razvoj v kronično rano, ki lahko ulcerira in vodi v maligno spremembo. Še posebej moramo biti pozorni pri opeklinskih ranah ter brazgotinah. Če se pojavi kronična rana, je potrebna biopsija in kasnejše zdravljenje. Uspešnost zdravljenja je bila največja, kadar se je rana obravnavala, še preden se je preobrazila.
Zastrupitev z ricinom: prikaz primera
Authors: Razinger Gašper , Brvar Miran
Published: July 2020

Kloščevec (Ricinus communis) v Sloveniji poznamo predvsem kot okrasno rastlino, medtem ko v toplejših delih sveta raste prosto v naravi kot plevel. Rastlina je v celoti strupena, saj vsebuje močan strup ricin, katerega največja koncentracija se nahaja v semenih. Kloščevec je gospodarsko pomemben za proizvodnjo ricinusovega olja.

V prispevku je opisan bolnik, ki se je zastrupil z zaužitjem semen kloščevca. Zastrupitev z  ricinom je potekala z omotico, glavobolom, bolečino v prsnem košu, dušenjem, slabostjo, bruhanjem in odvajanjem tekočega blata.

Ricin je toksični protein in je eden najmočnejših znanih rastlinskih strupov. Mehanizem njegovega delovanja je zavora sinteze proteinov v celici. Z ricinom se lahko zastrupimo z zaužitjem, vdihom, preko kože in vnosom v podkožje ali v mišice. Način vnosa pogojuje smrtni odmerek in klinično sliko. Zdravljenje zastrupitve z ricinom je simptomatsko. Skrbi nas uporaba ricina v teroristične namene, predvsem v obliki aerosola. V razvoju sta aktivna in pasivna imunizacija.
Dialéctica negativa y reflexión crítica: el problema moral en la filosofía y la teoría social de Theodor W. Adorno
Authors: Ipar Ezequiel
Published: July 2020

La crítica del sujeto moral realizada por Adorno resulta clave para comprender su proyecto filosófico. Por un lado, permite reconstruir los momentos esenciales de su crítica a la filosofía del sujeto. Pero la crítica moral también ofrece la posibilidad de realizar una indagación más formal de su obra, dado que la misma figura como uno de los objetos privilegiados de la Dialéctica Negativa. De este modo, al revisar su crítica moral uno tiene la oportunidad de plantear la difícil pregunta por la forma de esa filosofía que se presenta a sí misma como una dialéctica que exacerba la negatividad del pensamiento.
“Le debemos un gallo a Asclepio”. El canto político del cisne socrático
Authors: Bieda Esteban
Published: July 2020

Mucho se ha escrito acerca del significado de las últimas palabras de Sócrates en el Fedón(118a7-8): “Critón, debemos un gallo a Asclepio. Pues bien, ¡páguenselo! Y no se descuiden…”. En el presente trabajo nos proponemos retomar el enigma de la deuda con Asclepio a fin de rescatar cierto matiz político presente en él. Para ello, tras reseñar brevemente las principales interpretaciones que se han dado en el último siglo, nos detendremos en la concepción socrática del nacimiento y de la vida en tanto fenómenos eminentemente políticos para, a partir de allí, repensar el statusde su muerte en esa misma clave.
Revisión sistemática de intervenciones en prosocialidad y empatía en personas con TEA
Authors: Bru Luna Lluna María , Martí-Vilar Manuel , González Sala Francisco
Published: July 2020

El DSM-5 enmarca el trastorno del espectro autista (TEA) dentro de los trastornos del desarrollo neurológico, cuyo rasgo más característico son las alteraciones de la conducta social, que incluyen afectaciones en prosocialidad y empatía. El objetivo del presente trabajo es determinar la efectividad de las diferentes intervenciones dirigidas a mejorar la prosocialidad y la empatía en personas con TEA e identificar factores determinantes. Para ello, se ha llevado a cabo una revisión sistemática según las directrices PRISMA de los artículos encontrados en las bases de datos Web of Science, PubMed, ScienceDirect y Dialnet. Los resultados indican un incremento en las puntuaciones en prosocialidad y empática para las personas con TEA mediante diferentes técnicas de intervención, aunque parece ser que los factores determinantes son el grado de lenguaje receptivo y expresivo, las habilidades de comunicación no verbal, el razonamiento fluido, el CI y la frecuencia en la implementación.

The DSM-5 frames the autism spectrum disorder (ASD) within the neurodevelopmental disorders, whose most characteristic features are the alterations of social behavior. These include affectations in prosociality and empathy. The objective of this study is to determine the effectiveness of the different interventions aimed at improving prosociality and empathy in people with ASD and identifying determining factors for it. To this end, a systematic review of the articles found in the Web of Science, PubMed, ScienceDirect and Dialnet databases has been carried out following the PRISMA guidelines. The results indicate that an increase in prosociality and empathy scores for people with ASD is possible through different intervention techniques, and it seems that the determining factors are the degree of receptive and expressive language, nonverbal communication skills, fluid reasoning, IQ and the frequency of implementation.
Improved Bounds for Track Numbers of Planar Graphs
Authors: Pupyrev Sergey
Published: July 2020

A track layout of a graph consists of a vertex coloring and a total order of each color class, such that
no two edges cross between any two color classes. The track number of a graph is the minimum number
of colors required by a track layout of the graph.

This paper improves lower and upper bounds on the track number of several families of planar graphs. We prove that every planar graph
has track number at most $225$ and every planar $3$-tree has track number at most $25$. Then we show that there exist outerplanar graphs
whose track number is $5$, which leads to the best known lower bound of $8$ for planar graphs.
Finally, we investigate leveled planar graphs and tighten bounds on the track number of weakly leveled graphs, Halin graphs, and X-trees.
Breathing Life into Sexuality Education: Becoming Sexual Subjects
Authors: Allen Louisa
Published: July 2020

This paper thinks with Todd’s (2017) ideas around ‘breathing life into education’ in relation to the curriculum area of sexuality education. It explores how this metaphor might be employed as a method for re-animating thought about the nature and purpose of sexuality education. The paper argues that sexuality education suffers from the stifling effects of instrumentalism and a neoliberal normativity that seeks to micro-manage the lives of students. Within sexuality education, this finds expression in a repetitive emphasis on reducing unplanned pregnancies and sexually transmissible infections. Confined by these foci, sexuality education’s pedagogical possibilities and transformative potential are limited. Breathing life into sexuality education offers opportunities for shaping this curriculum area as sensuous event. It also provides a life-enhancing pedagogical orientation that shifts focus from determining student’s imagined sexual futures, to attending to uncertainty in the present. Thinking with Todd’s ideas within the realm of sexuality education is an attempt to exercise their utility within a specific curriculum context. The paper also endeavours to press the metaphor of breath further, to characterise it as an act that is both mundane and profound. The implications of this conceptualisation for thinking about change in sexuality education are explored.
Time War: Paul Virilio and the Potential Educational Impacts of Real-Time Strategy Videogames
Authors: Waddington David I.
Published: July 2020

This essay explores the possibility that a particular type of video game—real-time strategy games—could have worrisome educational impacts.In order to make this case, I will develop a theoretical framework originally advanced by French social critic Paul Virilio. In two key texts, Speed and Politics (1977) and “The Aesthetics of Disappearance” (1984), Virilio maintains that society is becoming “dromocratic” – determined by and obsessed with speed. Extending Virilio’s analysis, I will argue that the frenetic, ruthless environment of real-time strategy games may promote an accelerated, hypermodern way of thinking about the world that focuses unduly on efficiency.
What to do With Eurocentric Curricula: An Example From ‘Antigone in Ferguson’
Authors: Chang David
Published: July 2020

In their study of curriculum, teacher candidates often witness the pitfalls of Eurocentric curricula. This critical awareness of hidden biases is vital in a pluralistic society that is only now recognizing its colonial history. Indigenous communities are making bold strides in decolonizing their schools. Their notable efforts instantiate many forms of resistance to Eurocentrism in education. At the same time, there are examples in which marginalized groups seize the cultural goods of a dominant culture and assert their voice through the words of a canonized text. In this essay, I reflect on a modern interpretation of Sophocles’ Antigone and consider its relevance to curriculum studies.
Méthodologies en Administration publique : analyse comparative de la recherche au
Canada et en Australie
Authors: Charbonneau1 Étienne , Zekri Catherine , Castellanos Mariana , Kimvi Serguei  M. , Saël Emmanuel , Pli D. Abel , Ainsley Luc , Adandé2 H. Victor
Published: July 2020

Plusieurs études relèvent une diversification des méthodes en Administration
publique contemporaine. Cette étude fait un état des lieux systématique et comparé,
sur une décennie, des méthodes de recherche publiées dans deux revues nationales en
administration publique. Les recherches publiées en Administration publique au
Canada, ainsi qu’en Australie, semblent en décalage sur la communauté mondiale en
Administration publique au plan méthodologique. Notre revue systématique révèle
toutefois peu de différences entre les deux revues : les entrevues et analyses
qualitatives de contenu sont courantes dans les deux échantillons, mais les
techniques quantitatives utilisées demeurent élémentaires. Il s’agit d’une
particularité qui n’est pas partagée avec la recherche en science politique
canadienne.
Managing Morality and Building “Balance”: Depoliticisation as Management in Canada’s Federal Response to R. v. Morgentaler
Authors: Vachon1 Rebecca
Published: July 2020

In 1988, Canada’s federal Parliament faced the challenge of addressing the legal status of abortion after the Supreme Court of Canada, inR. v. Morgentaler, struck down existing restrictions. In the resulting legal void, the Progressive Conservative (PC) federal government found itself under pressure to act. Examining parliamentary debates and recently released cabinet documents from the period of January 1988 to May 1990, this paper asks how the federal government managed the abortion issue followingR. v. Morgentaler, including creating and defending legislation as a policy solution. This paper identifies politicising and depoliticising procedures (i.e., legislation and motions) that framed the issue in a way that that allowed the government to take action on the abortion issue while maintaining distance as it crafted and defended legislation. This paper reconstructs the frames that presented government legislation (Bill C-43) as “balanced” and uses the theoretical concepts of politicisation and depoliticisation to show how the frames alternately pushed and pulled the government towards and away from the abortion issue. These frames worked by deferring responsibility to other levels of government and the private sphere, as well as by invoking fatalism by highlighting the intransigency of abortion, the constraints that limit government action, and the necessity of pursuing only the government’s proposed solution. Although the frames serve to justify the frame of a “balanced” solution, their inherent contradictions and tensions point to fractures within the narrative of Bill C-43 as a “balanced” solution and may help explain the legislation’s failure.
Reform of the International Monetary System
Authors: Taylor John B.
Published: July 2020

An argument that a rules-based reform of the international monetary system, achieved by applying basic economic theory, would improve economic performance.

In this book, the economist John Taylor argues that the apparent correlation of monetary policy decisions among different countries—largely the result of countries' concerns about the exchange rate—causes monetary policy to deviate from effective policies that stabilize inflation and the economy. He argues that a rules-based reform of the international monetary system, achieved by applying basic economic theory, would improve economic performance.

Taylor shows that monetary polices in recent years have been deployed either defensively, as central banks counteract forces from abroad that affect the exchange rate, or offensively, as central banks attempt to move the exchange rate to gain a competitive advantage. Focusing on the years from 2005 to 2017, he develops an empirical framework to examine two monetary policy instruments: the policy interest rate (the more conventional of the two) and the size of the balance sheet. He finds that an international contagion in central bank decisions about the policy interest rate has accentuated the deviation from standard interest rate rules that have worked in the past. He finds a similar contagion in decisions about the size of the balance sheet. By considering a counterfactual policy in the estimated model, Taylor is able to estimate by how much the policy of recent years has increased exchange rate volatility. After several rounds of monetary actions and reactions aimed at exchange rates, Taylor finds, the international monetary system is left with roughly the same interest rate configuration, but much larger balance sheets to unwind.
Cancer systems immunology
Authors: Reticker-Flynn Nathan E , Engleman Edgar G
Published: July 2020

Tumor immunology is undergoing a renaissance due to the recent profound clinical successes of tumor immunotherapy. These advances have coincided with an exponential growth in the development of –omics technologies. Armed with these technologies and their associated computational and modeling toolsets, systems biologists have turned their attention to tumor immunology in an effort to understand the precise nature and consequences of interactions between tumors and the immune system. Such interactions are inherently multivariate, spanning multiple time and size scales, cell types, and organ systems, rendering systems biology approaches particularly amenable to their interrogation. While in its infancy, the field of ‘Cancer Systems Immunology’ has already influenced our understanding of tumor immunology and immunotherapy. As the field matures, studies will move beyond descriptive characterizations toward functional investigations of the emergent behavior that govern tumor-immune responses. Thus, Cancer Systems Immunology holds incredible promise to advance our ability to fight this disease.
Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells
Authors: Bennstein Sabrina Bianca , Weinhold Sandra , Manser Angela Riccarda , Scherenschlich Nadine , Noll Angela , Raba Katharina , Kögler Gesine , Walter Lutz , Uhrberg Markus
Published: July 2020

Despite their identification several years ago, molecular identity and developmental relation between human ILC1 and NK cells, comprising group 1 ILCs, is still elusive. To unravel their connection, thorough transcriptional, epigenetic, and functional characterization was performed from umbilical cord blood (CB). Unexpectedly, ILC1-like cells lacked Tbet expression and failed to produce IFNγ. Moreover, in contrast to previously described ILC1 subsets they could be efficiently differentiated into NK cells. These were characterized by highly diversified KIR repertoires including late stage NKG2A-KIR+ effector cells that are commonly not generated from previously known NK cell progenitor sources. This property was dependent on stroma cell-derived Notch ligands. The frequency of the novel ILC1-like NK cell progenitor (NKP) significantly declined in CB from early to late gestational age. The study supports a model in which circulating fetal ILC1-like NKPs travel to secondary lymphoid tissues to initiate the formation of diversified NK cell repertoires after birth.
Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin
Authors: Kelley Charlotte F , Litschel Thomas , Schumacher Stephanie , Dedden Dirk , Schwille Petra , Mizuno Naoko
Published: July 2020

Focal adhesions (FA) are large macromolecular assemblies which help transmit mechanical forces and regulatory signals between the extracellular matrix and an interacting cell. Two key proteins talin and vinculin connecting integrin to actomyosin networks in the cell. Both proteins bind to F-actin and each other, providing a foundation for network formation within FAs. However, the underlying mechanisms regulating their engagement remain unclear. Here, we report on the results of in vitro reconstitution of talin-vinculin-actin assemblies using synthetic membrane systems. We find that neither talin nor vinculin alone recruit actin filaments to the membrane. In contrast, phosphoinositide-rich membranes recruit and activate talin, and the membrane-bound talin then activates vinculin. Together, the two proteins then link actin to the membrane. Encapsulation of these components within vesicles reorganized actin into higher-order networks. Notably, these observations were made in the absence of applied force, whereby we infer that the initial assembly stage of FAs is force independent. Our findings demonstrate that the local membrane composition plays a key role in controlling the stepwise recruitment, activation, and engagement of proteins within FAs.
Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability
Authors: Voskobiynyk Yuliya , Roth Jonathan R , Cochran J Nicholas , Rush Travis , Carullo Nancy VN , Mesina Jacob S , Waqas Mohammad , Vollmer Rachael M , Day Jeremy J , McMahon Lori L , Roberson Erik D
Published: July 2020

Genome-wide association studies identified the BIN1 locus as a leading modulator of genetic risk in Alzheimer’s disease (AD). One limitation in understanding BIN1’s contribution to AD is its unknown function in the brain. AD-associated BIN1 variants are generally noncoding and likely change expression. Here, we determined the effects of increasing expression of the major neuronal isoform of human BIN1 in cultured rat hippocampal neurons. Higher BIN1 induced network hyperexcitability on multielectrode arrays, increased frequency of synaptic transmission, and elevated calcium transients, indicating that increasing BIN1 drives greater neuronal activity. In exploring the mechanism of these effects on neuronal physiology, we found that BIN1 interacted with L-type voltage-gated calcium channels (LVGCCs) and that BIN1–LVGCC interactions were modulated by Tau in rat hippocampal neurons and mouse brain. Finally, Tau reduction prevented BIN1-induced network hyperexcitability. These data shed light on BIN1’s neuronal function and suggest that it may contribute to Tau-dependent hyperexcitability in AD.
Quantification of the Effects of Strain Rate and Nano-Reinforcement on the Performance of Adhesively Bonded Single-Lap Joints
Authors: Soltannia B. , Duke K. , Taheri F. , Mertiny P.
Published: July 2020

The aim of this study is to present an efficient and effective technique to strategically investigate and classify the influence of a set of manipulated parameters that affect the mechanical properties and performance of adhesively bonded joints formed by an adhesive that is reinforced
by various types of carbon nanoparticles (NPs). Specifically, single-lap joints (SLJs) are considered in this study. The selected parameters include the adherend types (i.e., carbon fiber-reinforced polymers (CFRPs) and glass fiber-reinforced polymers (GFRPs)), three types of nanoparticles
(i.e., carbon nanofibers (CNFs), multi-walled carbon nanotubes (MWCNTs) and graphene nanoplatelets (GNPs)), different weight-percent (wt.%) of GNPs (i.e., 0, 0.5, 1%), and three different strain (or loading) rates, classified as static, quasi-static and impact loadings, herein. The study employed
two mixed-level full factorial design of experiments (DOE) to evaluate the contribution of the aforementioned parameters, including the effect of their interactions on the enhancement of the averaged ultimate shear strength (AUSS) of the SLJs. The DOE study was conducted using the strength
data (AUSS) obtained through testing of 108 SLJ specimens. The results indicate that among the considered parameters, NPs (wt%), adherend type, and strain rate had a greater effect on AUSS. According to the DOE conducted in this study, the greatest AUSS (19.9 MPa) could be obtained when 1.0
wt% GNP was used to reinforce the SLJs with CFRP adherend and subjected to the highest strain rate (HSR). This combination yielded a 32% enhanced AUSS compared to the SLJs formed by the neat adhesive.
Bioadhesives in Biomedical Applications: A Critical Review
Authors: Dey Aishee , Bhattacharya Proma , Neogi Sudarsan
Published: July 2020

The necessity for a long time contact between the drug and mucus layer/epithelial cell or a combination of the two requires a bioadhesive. A bioadhesive is known to intensify contact between the two and help in controlled release of drugs. The conventionally used bioadhesives are known
to have poor adhesion strength and can have toxic side effects. This review focuses on the various types of polymers and their composites for use as bioadhesives which can overcome the previously mentioned issues. These include some naturally occurring bioadhesives such as collagen, chitosan,
albumin, dextran and some synthetic bioadhesives like gelatin, poly(ethylene glycol), poly(acrylic acid), poly(lactic-co-glycolic acid) based bioadhesives. The clinical trials prove the effectiveness of these bioadhesives and they are found to be more efficient than the commercial glues and
hence possess great potential for use in the biomedical industry.
High frequency direct shoot regeneration from Kazakh commercial potato cultivars
Authors: Abeuova Laura S. , Kali Balnur R. , Rakhimzhanova Aizhan O. , Bekkuzhina Sara S. , Manabayeva Shuga A.
Published: July 2020

Potato (Solanum tuberosum L.) is the third most economically important crop in the world and has a high nutritional value. In this study, the in vitro culture response of four widely grown in Kazakhstan potato cultivars, Astanalyk, Monument Kunaev, Tokhtar, and Aksor, was investigated using stem and leaf explants. Published protocols were evaluated and optimized to develop a more efficient protocol for the regeneration of plants from local potato cultivars in tissue culture, which is a prerequisite to facilitate potato genome modification. The explants were cultured on solid Murashige and Skoog medium supplemented with different concentrations and combinations of zeatin, 6-benzylaminopurine (BAP), gibberellic acid (GA3), 1-naphthaleneacetic acid (NAA) and indole-3-acetic acid (IAA). The maximum regeneration was induced from the stem internodal explants. A significant effect of the explant source on direct regeneration was confirmed with statistical analysis. The number of shoots obtained from the internode was 10.0 from cv. Aksor followed by cvs. Tokhtar and Astanalyk. The medium DRM-VIII with 1 mg/l zeatin, 0.1 mg/l IAA and 7.0 mg/l GA3 was considered the best for direct shoot regeneration and multiple shoot formation from all cultivars. To conclude, we outline a protocol for direct plant regeneration from four potato cultivars. Our findings suggest commercial cultivars Astanalyk and Aksor are good candidates for developing the genome-edited plants through direct shoot regeneration.
Accessing and Utilizing One’s City Space: The Role of Specialized Community Mental Health Teams in Brazil and Canada
Authors: Khoury Emmanuelle , Ruelland Isabelle
Published: July 2020

Community mental health programs have garnered significant attention during the last decade. In this paper we ask to what extent these programs impact the capacity of service users to move around in the city space. Drawing on case studies from ethnographic research conducted in Campinas (Brazil) and Montréal (Canada), which included semi-structured interviews with a total of 16 service users and 49 mental health professionals, we explore the significance of urban mobility as part of service users’ mental health recovery and service providers’ practice. Findings suggest that service providers play a key role in facilitating meaningful mobility in the city space.
Plastic Consumption in Group of Teens and Young Adults from Pangandaran District, Indonesia: A Glimpse of Environmental Awareness among the Locals outside Big Cities
Authors: Permana Rega , Rizal Achmad , Hasan Zahidah
Published: July 2020

In this research we tried to get an understanding of plastic consumption behavior in a relatively remote area, Pangandaran district Indonesia, especially on teens and young adults to evaluate their environmental awareness. Volunteers were asked to note down their plastic consumption for over 31 days and differentiate it in three different types of plastic waste that are plastic bottles, plastic bags, and plastic packaging. Results showed that plastic consumption in teens and young adults of the Pangandaran District is still inevitable although they are already exposed to the knowledge of plastic waste impacts. The usage accounted for up to 5 plastics per day. A fluctuating pattern of plastic used was found predominantly for three types of plastic waste with the plastic packaging topping the consumption, followed by the plastic bottle and plastic bag. We hypothesized that the idea of plastic detrimental effects is already known in the group, however the plastic consumption still an unavoidable option since there is no choice and straight law enforcement in the district. This putting the teens and young adults of Pangandaran District at the conscious incompetence category, according to the psychological theory of competence.
Modeling the Diffraction of Electromagnetic Waves over Underwater Objects; the Wiener-Hopf Integral Equation
Authors: Warnapala Yajni , Foster Cole
Published: July 2020

This research, inspired by the loss of Malaysian Airline Flight 370, investigates the feasibility of obtaining good convergence results for a model of the interaction of electromagnetic waves over the surface of the Spherical Biconcave Disc. The Galerkin Method is used to numerically solve the Dirichlet and Neumann exterior boundary value problems for the Wiener-Hopf Integral Equation over the half-plane of the Spherical Biconcave Disc. This modeling accounts for the attenuation losses of the propagating electromagnetic wave as a result of absorption and scattering in lossy media with comparison to lossless propagation. The numerical results of this research nds good convergence for this model as well as limitations in the transmission of electromagnetic waves underwater.
Hansen’s disease patients’ perceptions on their altered fundamental human needs: indications for self-care
Authors: Palmeira Iací Proença , Moura Jamilly Nunes , Epifane Suelen Gaia , Ferreira Angela Maria Rodrigues , Boulhosa Margarete Feio
Published: July 2020

Objetivo: Analisar a percepção de pacientes com hanseníase sobre suas necessidades humanas básicas (NHB) alteradas. Método: Pesquisa qualitativa e descritiva, realizada com dez pacientes inscritos no Programa Nacional de Controle da Hanseníase (PNCH) em uma Unidade Básica de Saúde (UBS) em Belém-PA. Dados coletados de agosto a setembro de 2017, por meio de entrevista semiestruturadas e prontuários dos participantes. Os dados foram organizados e analisados na perspectiva da análise de conteúdo. A pesquisa foi aprovada, sob o nº 2.148.415/23.06.2017, pelo CEP da Escola de Enfermagem Magalhães Barata. Resultados: foram detectadas cinco necessidades alteradas: necessidades fisiológicas, de segurança, de amor e/ou sociais, de estima e de autorrealização. Evidenciou-se que a percepção das NHB alteradas estimula ações de autocuidado, com vistas a sua satisfação. Conclusão: O enfermeiro deve prestar cuidados humanizados ao paciente com hanseníase, motivando-os para a autonomia e para o autocuidado, contribuindo para a melhoria da qualidade de vida.
Evolution of healing ulcers in the lower limbs of patients using Unna boot associated with shiatsu
Authors: Aguiar Janne Karlla de , Guedes Helisamara Mota , Lara Maristela Oliveira , Stuchi Rosamary Aparecida Garcia , Lucas Thabata Coaglio , Martins Dulce Aparecida
Published: July 2020

Objetivo: Avaliar a evolução da cicatrização de úlceras nos membros inferiores de pacientes em uso de bota de Unna associada ao shiatsu. Método: Estudo de caso realizado na Policlínica Regional no interior de Minas Gerais com sete indivíduos portadores de úlceras nos membros inferiores. A coleta de dados foi realizada durante o tratamento associado a terapia alternativa/complementar shiatsu. Os dados foram analisados por estatística descritiva. Resultados: A média de idade foi de 61,5 anos, dentre as patologias de base, seis tinham diabetes mellitus, quatro eram hipertensos. Na avaliação dos membros inferiores, observou-se: área média inicial da ferida: 73 cm2 área média final 24 cm2. PUSH inicial 14,8 e final 8,8. Dor inicial 2,7 e final 0,14. Conclusão: Percebeu-se redução na área das feridas, na intensidade da dor, e no número de feridas, indicando que o tratamento convencional associado a terapia alternativa complementar pode ser benéfico.
The oral health of international undergraduates: importance, knowledge and conducts towards oral pathologies
Authors: Benedito Francisco Cezanildo Silva , Joaquim Davide Carlos , Silva N'ghalna da , Cruz Gabriela Silva , Farias Ana Gesselena da Silva , Leite Ana Caroline Rocha de Melo
Published: July 2020

Objetivo: Investigar a importância da saúde bucal e a frequência e os meios utilizados na higienização da cavidade oral, assim como o conhecimento e as condutas de universitários frente às doenças bucais. Método: Estudo descritivo e qualitativo desenvolvido com universitários de diferentes nacionalidades. Os dados foram coletados pela aplicação de questionário. Resultados: Para os participantes, a importância da saúde bucal estava vinculada à prevenção de doenças, à estética, à autoestima e à saúde geral. Quanto à frequência e aos meios utilizados na escovação, todos higienizavam a cavidade oral diariamente e a maioria utilizava escova e creme dental. Eles associavam as doenças orais à dor, ao sangramento, aos problemas dentários e à falta de escovação. Além do dentista, buscavam o médico e o enfermeiro para resolução de problemas odontológicos. Conclusão: Apesar de reconhecerem a importância da saúde oral, o conhecimento dos universitários sobre as patologias bucais foi escasso e muito limitado.
Comparative study on the conditions of anemia in elderly
Authors: Jesus Andreia Souza de , Almeida Claudio Bispo de , Santos Djanilson Barbosa dos , Jesus Cleber Souza de , Casotti Cezar Augusto
Published: July 2020

Objetivo: Comparar características sociodemográficas, comportamentais, condições de saúde e parâmetros laboratoriais entre idosos anêmicos e não anêmicos. Métodos: Estudo epidemiológico transversal realizado com 257 idosos. Para realizar as comparações utilizou-se o teste t para amostras independentes e o teste não paramétrico U de Mann-Whitney. Resultados: Encontrou-se maior proporção de anemia em idosos com idade acima de 80 anos (p=0,026), e maior proporção de dependência para atividades básicas (p=0,018) e instrumentais (p=0,010) da vida diária em idosos com anemia. Identificou-se diferença na distribuição da dosagem dos parâmetros laboratoriais, sendo as concentrações médias de ureia e creatininamaiores nos idosos anêmicos, e esses tiveram menores concentrações de glicemia, albumina, ALT/TGP, cálcio sérico e T3 total. Conclusão: A anemia não está relacionada exclusivamente ao processo de envelhecimento, mas sim resultado de múltiplos fatores como as condições sociodemográficas, de saúde, alimentares e de vida dos idosos. Descritores: Anemia, Hemoglobina, Envelhecimento