bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the Clinical Laboratory Indexes in COVID-19 Patients with Ocular Symptoms in Iran: A Single-Center Experience
Authors: Rasoulinejad Seyed Ahmad
Published: March 2022

Objectives: Ocular symptoms are prevalent in coronavirus infectious disease 2019 (COVID-19) patients, which may be related to clinical/paraclinical conditions. This study investigated the association between laboratory indexes and ocular symptoms in COVID-19 patients. Methods: In this cross-sectional study, 108 polymerase chain reaction (PCR)-confirmed COVID-19 patients admitted to the Rouhani Hospital, Babol, Iran, were enrolled. Ocular symptoms were investigated using standard ophthalmologic examinations. Routine laboratory investigation was done according to the standard management in patients with COVID-19 infection. Results: The erythrocyte sedimentation rate (ESR) and the serum levels of the blood urea nitrogen (BUN) and creatinine (Cr) were significantly higher in COVID-19 patients with ocular discharge and exudate (P = 0.002, 0.045, 0.046, and 0.027, respectively), while the red blood cell (RBC) and albumin were lower in COVID-19 patients with ocular discharge and exudate (P = 0.029 and 0.027, respectively). The serum levels of creatine kinase (CPK) and iron (Fe) were significantly higher in non-photophobic COVID-19 patients than in photophobic patients (P =0.033 and 0.050, respectively). In contrast, the serum level of procalcitonin was lower than photophobic COVID-19 patients (P = 0.024). The serum level of phosphorus (P) was significantly higher in COVID-19 patients with itchy eyes compared to COVID-19 patients without itchy eyes (P = 0.026). Conclusions: The footprint of laboratory indexes was demonstrated in ocular symptoms of COVID-19 patients. The kidney biomarkers were correlated with ocular discharge and exudate, and electrolytes were associated with tear-related symptoms.
Considering the Costs of Signing an NDA
Authors: Bhalloo Shafik , Burke Kathleen ,   Neilson Journals Publishing
Published: March 2022

With her heavy-equipment operator certification in hand, Fiona is a new hire on a construction crew; the only woman in a family-owned organization aside from the HR manager, the sister of the company president and vice-president. Soon after her hire, the president of the company began a pattern of sexually targeting Fiona. She went to great lengths to avoid her boss, but the harassment and assaults continued. After one incident, Fiona reported the abuse to the company VP who offered her a financial settlement in exchange for her silence. Fiona thought speaking out would put an end to the strain the abuse had caused, but other dilemmas had just begun. The case allows students to examine the competing interests Fiona faces in deciding whether to accept a financial settlement from her employer, that would greatly help her family, but at the cost of signing a non-disclosure agreement.
What Makes Ethics Education Effective?
Authors: Gulseren Duygu , Turner Nick , Weinhardt Justin M. ,   Neilson Journals Publishing
Published: March 2022

Ethics education remains in high demand in business schools. Meta-analyses published in the last two decades show that ethics instruction with certain characteristics produce more desirable moral outcomes than other characteristics do. Acknowledging the vast accumulated knowledge on this topic, we believe that the existing evidence base could be overwhelming for ethics educators designing and delivering their courses. Thus, we review the research evidence on the effectiveness of ethics instruction and translate the findings into evidence-led best practices. Adopting the meta-science approach and using a model of training evaluation, we synthesized 8 meta-analyses and 3 quantitative reviews that examine the extent to which ethics instruction types, course duration, instructional techniques and activities, and instructor and student characteristics affect the effectiveness of ethics education. We conclude by making specific recommendations to ethics educators who are interested in designing and delivering evidence-based ethics courses.
Applying the Contemplative Technopedagogy Framework: Insights for Teaching Ethics Using TV Series
Authors: Shanks Justin D. , Scalzo Germán , Nicolás-Gavilán María Teresa ,   Neilson Journals Publishing
Published: March 2022

Digital media and technology are nearly ubiquitious in contemporary higher education, As such, researchers and educators are keen to identify best practices and understand impacts. Digital media and technology present opportunities to cultivate interactive, creative teaching-learning communities. However, inclusion of digital media and technology in a course does not necessarily cultivate creative engagement or deep reflection among students. This manuscript studies how a contemplative approach to teaching with digital media, specifically TV series, can lead to more effective and engaging in the process of teaching professional ethics. This research explores how the Contemplative Technopedagogy Framework can enrich the use of TV series for teaching professional ethics and positively influence the effective integration of ethical behavior into university students’ future professional lives.
Labahitha spiders (Arachnida: Araneae: Filistatidae) from islands in the Indian and Pacific Oceans
Authors: Magalhaes Ivan L.F. , Berry James W. , Koh Joseph K.H. , Gray Michael R.
Published: March 2022

The genus Labahitha has hitherto comprised two species from peninsular Malaysia and Christmas Island (Australia). We here demonstrate that the genus is widespread in islands and territories across the Indian and Pacific Oceans, including the following species that have been previously assigned to other filistatid genera: Labahitha marginata (Kishida, 1936) comb. nov. (= Filistata bakeri Berland, 1938 syn. nov.), Labahitha garciai (Simon, 1892) comb. nov. (= Pritha heikkii Saaristo, 1978 syn. nov., = Pritha sechellana Benoit, 1978 syn. nov.), Labahitha nicobarensis (Tikader, 1977) comb. nov., Labahitha littoralis (Roewer, 1938) comb. nov., Labahitha insularis (Thorell, 1891) comb. nov., Labahitha sundaica (Kulczyński, 1908) comb. nov. (all transferred from Pritha, the latter three provisionally, pending re-examination of the type material); Labahitha fuscata (Nakatsudi, 1943) comb. nov. and Labahitha ryukyuensis (Ono, 2013) comb. nov. (both transferred from Tricalamus). Many of these species have been collected in synanthropic settings and from disparate islands thousands of kilometers apart. This suggests either high dispersal capabilities or, more likely, human-mediated introductions. At least L. marginata has been introduced to continental America. Two new species of Labahitha are described: Labahitha platnicki sp. nov. from New Caledonia and the Bismarck Islands and Labahitha incerta sp. nov. from Queensland, Australia. The male of Labahitha gibsonhilli (Savory, 1943) is reported for the first time. Wandella loloata sp. nov. is described from Papua New Guinea, representing the first record of this genus outside Australia. Pritha hasselti (Simon, 1906) from Indonesia is shown to be a Filistatinae, and thus the species is provisionally transferred back to Filistata.
A Computer-Aided Diagnosis System of Fetal Nucleated Red Blood Cells With Convolutional Neural Network
Authors: Sun Chao , Wang Ruijie , Zhao Lanbo , Han Lu , Ma Sijia , Liang Dongxin , Wang Lei , Tuo Xiaoqian , Zhang Yu , Zhong Dexing , Li Qiling
Published: March 2022

Context.—

The rapid recognition of fetal nucleated red blood cells (fNRBCs) presents considerable challenges.

Objective.—

To establish a computer-aided diagnosis system for rapid recognition of fNRBCs by convolutional neural network.

Design.—

We adopted density gradient centrifugation and magnetic-activated cell sorting to extract fNRBCs from umbilical cord blood samples. The cell-block method was used to embed fNRBCs for routine formalin-fixed paraffin sectioning and hematoxylin-eosin staining. Then, we proposed a convolutional neural network–based, computer-aided diagnosis system to automatically discriminate features and recognize fNRBCs. Extracting methods of interested region were used to automatically segment individual cells in cell slices. The discriminant information from cellular-level regions of interest was encoded into a feature vector. Pathologic diagnoses were also provided by the network.

Results.—

In total, 4760 pictures of fNRBCs from 260 cell-slides of 4 umbilical cord blood samples were collected. On the premise of 100% accuracy in the training set (3720 pictures), the sensitivity, specificity, and accuracy of cellular intelligent recognition were 96.5%, 100%, and 98.5%, respectively, in the test set (1040 pictures).

Conclusions.—

We established a computer-aided diagnosis system for effective and accurate fNRBC recognition based on a convolutional neural network.
The clinical diagnostic value of plasma miR-592 and miR-217-3p levels in retinoblastoma
Authors: Yan Luo , Lin Huang , Yu Hu , Jie Li , Chen Jun , Mei Yuan , Peng Yuan
Published: March 2022

Background: This study was designed to investigate the abnormal expression of plasma miR-592 and miR-217-3p in retinoblastoma (Rb) and explore the clinical diagnostic value of their expression levels for Rb. Methods: The 100 Rb patients who came to Nanchang Hongdu Hospital of Traditional Chinese Medicine from January 2018 to January 2019 were selected as the Rb group, and 100 healthy patients who came to the physical examination centre during the same period were selected as the control group. Real-time fluorescence quantitative PCR (qRT-PCR) was used to detect the expression levels of plasma miR-592 and miR-217-3p in all subjects; analyse the relationship between plasma miR-592 and miR-217-3p levels and the clinicopathological characteristics of Rb. Pearson correlation analysis evaluated the relationship between plasma miR-592 and miR-217-3p levels and overall survival. Results: Plasma levels of miR-592 and miR-217-3p in the Rb group were significantly higher than those in the control group (p<0.0001), and the expression of miR-592 was significantly correlated with family genetic history (p 0.0001), tumour bias (p=0.0081), lymph node metastasis (p=0.0048) and pathological grade (p=0.0025), and the expression of miR-217-3p was significantly related to family genetic history (p 0.0001), optic nerve infiltration (p 0.0001), lymph node metastasis (p=0.0090), and pathological grade (p 0.0001). The high expression of miR-592 and miR-217-3p presents a more serious pathological manifestation of Rb, and the overall survival of patients is significantly shortened with the increase of miR-592 (r=-0.2276, p=0.0052) and miR-217-3p levels (r=-0.6461, p 0.0001). Conclusions: and miR-217-3p are highly expressed in the plasma of Rb patients, and their elevated levels present severe pathological manifestations of Rb and shortened overall survival, which is expected to become biomarkers for clinical diagnosis of Rb.
Attitudes shape implicit temporal trajectories: A quantitative test of the narrative structure of collective memories of colonialism
Authors: Lastrego Simona , Janssens Charlotte , Klein Olivier , Licata Laurent
Published: March 2022

This article investigates how Belgian participants’ implicit temporal trajectories regarding the history of Belgian colonialism in the Congo vary as a function of their attitudes towards colonialism and thus create different collective memories. We reasoned that, depending on their attitudes towards Belgian colonialism, individuals may draw on different schematic narrative templates to structure their own implicit temporal trajectory of colonial history. Consequently, we predicted that the shape of individual implicit temporal trajectories should vary according to their attitudes. Specifically, we expected that positive attitudes towards colonialism would be associated with implicit temporal trajectories in which the colonial period is seen as more positive than before and after colonialism, creating an inverted U-shaped implicit temporal trajectory, while negative attitudes towards colonialism should be associated with the opposite trend – U-shaped implicit trajectories. We measured the attitudes towards colonialism of Belgian participants (n = 129), then their social representations of three historical periods: before, during and after Belgian colonialism. Overall, results supported these hypotheses. This study complements previous narrative psychology investigations by bringing quantitative evidence according to which collective memories are structured as implicit temporal trajectories that are in line with people’s attitudes.
imagen de Cuba en la guerra de 1898.
Authors: Mazorra Ruiz Danislady
Published: March 2022

In 1898, the United States declared war on Spain and "came to the aid" of the Cubans in the liberation struggle they had begun in 1895 against Spain. These events aroused a wide media coverage. Although the differences are evident between the Spanish and American press, both countries pursue the same goal: to offer their vision of the conflict and ratify the hegemonic role they should play in it. Here we are interested in the image of Cuba in the journalistic satires and, in particular, the allegory of Cuba in the Spanish and American press. The intention is to discover the commonality of the forms, but also the symbolic discrepancies, so that the schemes of representation that transcend the immediacy of the political fact also emerge. The objective is, therefore, to deconstruct the visual process of symbolic construction of Cuba, and of the war that took place there, in the press in 1898.

En 1898, Estados Unidos le declara la guerra a España y “acude al auxilio” de los cubanos en la gesta de liberación que habían iniciado en 1895 contra España. Estos sucesos despertaron un amplio despliegue mediático. Si bien las diferencias son evidentes entre la prensa española y estadounidense, en ambos países se persigue un mismo fin: ofrecer su visión del conflicto y ratificar el rol hegemónico que en él deben jugar. Aquí nos interesa la imagen de Cuba en las sátiras periodísticas y, en particular, la alegoría de Cuba en la prensa española y estadounidense. La intención es descubrir lo común de las formas, pero también las discrepancias simbólicas, para que emerjan también los esquemas de representación que trascienden la inmediatez del hecho político. El objetivo es, pues, deconstruir el proceso visual de construcción simbólica de Cuba, y de la guerra que en ella se desarrollaba, en la prensa en 1898.
Nature and Pandemic
Authors: Espinoza Lolas Ricardo
Published: March 2022

The article shows how the Covid-19 pandemic is not only a matter associated with nature, but it is an essential topic in order to understand humanity today, because at the beginning of the pandemic it was immediately shown that nature was behind this disaster, because it was, in a certain way, taking revenge on the humans. After all, the very conception of nature that we use today is a human conception, created from the subjectivity of the Self, that goes hand in hand with the modern creation of the nation-state. Nature, nation-state, etc., are creations of the Self and in this way nature is understood as something objective, but at the same time the human subject treats himself as an object. Here lies the very problem, because neither the Self nor the nature behave in an objective way, but both moments are made visible from a dynamic articulation of the movement of one in the other. This vision was part of the conception of the ancient Greeks and by Nietzsche and other current thinkers such as Žižek.
The Sexistential Vulnerability of Bodies in Contact in the Philosophy of Jean-Luc Nancy
Authors: Recchia Luciani Francesca Romana
Published: March 2022

The philosophy of sexual existence as a mode of expression of the “con-being”, pivotal in his book “Sexistence”, occupies a relevant space in Jean-Luc Nancy’s late philosophical production. In this text, the body, the touch, the sex are protrusions that dot a conceptual map that is the result of a long philosophical militancy marked by an authentic “haptic ontology”, a sign of a thought of relationality, interdependence and “sexistencial vulnerability” that connotes the bodies in contact that we all are. But Nancy goes so far as to elaborate a “trans-ontology” through which the “r-existence (resistance) of sexistence” is manifested, that is to say that stubborn rejection of distinct and different bodies to the homologation and uniformity of the identical and of the identity shared by “trans-feminism” which makes its strong point of the inexhaustible combinatorics of the sexes. Thus, both for the sexistencial approach and for the transfeminist one, at the heart of every theory are the lives and practices of distinct and different sexual bodies in relation.
Universal Design for Learning and Inclusive Teaching: Future Perspectives
Authors: Rossi Martina
Published: March 2022

This contribution aims to reflect on the didactic and methodological changes brought about by Distance Learning, with particular regard to the concept of Inclusive Teaching. During the last year, in fact, the epidemiological emergency dictated by Covid-19 has led to the emergence of new needs, imposing a redesign of tools and resources in use. All this has had a strong impact on students with disabilities and Specific Learning Disorders (SLD), who, in addition to having fewer digital skills than their European peers, were suddenly forced to follow lessons at home without the physical support of the teacher. It was necessary, in fact, to think and re-think about the design of inclusive educational interventions. From a methodological and conceptual point of view, Inclusive Teaching is linked to the concept of Universal Design for Learning (UDL), an inclusive psycho-pedagogical approach that aims to break down the barriers that exist in learning processes. During the pandemic period, one of the major challenges that scholars have begun to consider is applying the UDL approach, generally used in in-person classes, lectures and online courses.
The Vagaries of the Superego
Authors: Žižek Slavoj
Published: March 2022

Starting from the distinction between “ideal ego”, “ego-ideal” and “superego” structured from the Imaginary-Symbolic-Real triad made by Lacan, this study investigates how is possible to distinguish the a-sexual social space from the domain of libidinally-cathexed interactions. Through the analysis of Balibar’s, Miller’s, Schuster’s and Hägglund’s ideas, paths and strategies are defined to analyze the existing dynamics between symbolic power, law and superego. What emerges is the reconstruction of a new subjectivity which is capable, at the same time, to overcome the jouissance-superego dynamic at the basis of Lacanian reflection and face the challenges of contemporary post-humanism. Therefore, what subject stands for is the inhuman core of being-human, what Hegel called selfrelating negativity, what Freud called death drive. The text proposes, in short, how the Subject is what is in a human being more than human, the immortality of the deathdrive which makes it a living dead, something that insists beyond the cycle of life and death.
A weighted sparse coding model on product Grassmann manifold for video-based human gesture recognition
Authors: Wang Yuping , Zhang Junfei
Published: March 2022

It is a challenging problem to classify multi-dimensional data with complex intrinsic geometry inherent, such as human gesture recognition based on videos. In particular, manifold structure is a good way to characterize intrinsic geometry of multi-dimensional data. The recently proposed sparse coding on Grassmann manifold shows high discriminative power in many visual classification tasks. It represents videos on Grassmann manifold using Singular Value Decomposition (SVD) of the data matrix by vectorizing each image in videos, while vectorization destroys the spatial structure of videos. To keep the spatial structure of videos, they can be represented as the form of data tensor. In this paper, we firstly represent human gesture videos on product Grassmann manifold (PGM) by Higher Order Singular Value Decomposition (HOSVD) of data tensor. Each factor manifold characterizes features of human gesture video from different perspectives and can be understood as appearance, horizontal motion and vertical motion of human gesture video respectively. We then propose a weighted sparse coding model on PGM, where weights can be understood as modeling the importance of factor manifolds. Furthermore, we propose an optimization algorithm for learning coding coefficients by embedding each factor Grassmann manifold into symmetric matrices space. Finally, we give a classification algorithm, and experimental results on three public datasets show that our method is competitive to some relevant excellent methods.
Onyx disparamphis sp. n. (Nematoda, Desmodorida) from South Korea with a taxonomic review of the genus
Authors: Tchesunov Alexei V. , Jeong Raehyuk , Lee Wonchoel
Published: March 2022

A new free-living marine nematode Onyx disparamphis sp. n. (Nematoda, Desmodorida) is described from sandy littoral of Jeju Island, South Korea. The new species differs from all other Onyx species by the unusual amphideal fovea morphology in males (elongated loop). O. disparamphis relates to O. balochinensis, and O. brevispiculatum by having simple non-double terminal pharyngeal bulb and relatively small and straight, non-sigmoid supplementary organs, but differs from them by smaller body length, shorter cephalic setae, smaller terminal pharyngeal bulb, smaller spicules, number of supplementary organs and tail shape expressed as ratio tail length/anal diameter. The genus Onyx is revised with updated genus diagnosis, and an annotated list of 23 valid species is presented. Onyx ferox is considered species inquirenda because the species is known only from a sole immature female specimen, while within Onyx, the males provide the most important distinguishing characters such as enlarged and complicated amphids, supplementary organs and copulatory spicules. For species identification, a pictorial key consisting of illustrations of simplified icons of male heads and posterior body sections, as well as a table of the most important morphometric and numerical characters are provided. Geographical distribution and habitat specifity of Onyx species is analysed briefly.
Skin microbiota diversity among genetically unrelated individuals of Indian origin
Authors: Potbhare Renuka , RaviKumar Ameeta , Munukka Eveliina , Lahti Leo , Ashma Richa
Published: March 2022

Background

Human skin harbors complex transient and resident microbial communities that show intra- & inter-individual variation due to various environmental and host-associated factors such as skin site, diet, age, gender, genetics, or the type and use of cosmetics. This variation remains largely uncharacterized in the Indian population; hence, the present study aims to characterize the variation in skin microbiota among individuals of Indian origin and quantify associations with age, diet, and geography.

Methods

Axillary sweat samples from genetically unrelated individuals (N = 58) residing in the three geographical locations of Maharashtra, India, were collected using a sterile cotton swab. Bacterial DNA was extracted using a standard protocol and checked for quality. Variable regions (V3–V4) of the 16S rRNA gene were sequenced using the Illumina platform. We used standard methods from microbiota bioinformatics, including alpha and beta diversity, community typing, and differential abundance, to quantify the association of skin microbiota with age, diet, and geographical location.

Results

Our study indicated the prevalence of phyla- Firmicutes, Proteobacteria, and Actinobacteria, consistent with previous reports on skin microbiota composition of the world population level. The alpha diversity (Shannon index) was significantly associated with the age group (Kruskal–Wallis test, p = 0.02), but not with geography (p = 0.62) or diet (p = 0.74). The overall skin microbiota community composition was significantly associated with geographical location based on Community State Types (CST) analysis and PERMANOVA (R2 = 0.07, p = 0.01). Differential abundance analysis at the genus level indicated a distinctively high abundance of Staphylococcus and Corynebacterium among individuals of the Pune district. Pseudomonas and Anaerococcus were abundant in individuals from Ahmednagar whereas, Paenibacillus, Geobacillus, Virgibacillus, Jeotgalicoccus, Pullulanibacillus, Delsulfosporomusa, Citinovibrio, and Calditerricola were abundant in individuals from Nashik district.

Conclusion

Our work provides one of the first characterizations of skin microbiota variation in different sub-populations in India. The analysis quantifies the level of individuality, as contrasted to the other factors of age, geography, and diet, thus helping to evaluate the applicability of skin microbiota profiles as a potential biomarker to stratify individuals.
Whole-genome analysis of CGS, SAHH, SAMS gene families in five Rosaceae species and their expression analysis in Pyrus bretschneideri
Authors: Zhang Yang , Li Decong , Feng Xiaofeng , Wang Xinya , Wang Mengna , Han Wenlong , Manzoor Muhammad Aamir , Li Guohui , Chen Tianzhe , Wang Han , Cai Yongping
Published: March 2022

Cystathionine γ-synthase (CGS), S-adenosyl-L-homocysteine hydrolase (SAHH), and S-adenosy-L-methionine synthetase (SAMS) play an important role in the regulation of plant growth, development, and secondary metabolism. In this study, a total of 6 CGS, 6 SAHH, and 28 SAMS genes were identified from five Rosaceae species (Pyrus bretschneideri, Prunus persica, Prunus mume, Fragaria vesca, and Malus domestica). The evolutionary relationship and microsynteny analysis in five Rosaceae species revealed that duplicated regions were conserved between three gene families (CGS, SAHH, SAMS). Moreover, the chromosomal locations, gene structures, conserved motifs, cis-elements, physicochemical properties, and Ka/Ks analysis were performed by using numerous bioinformatics tools. The expression of different organs showed that the CGS, SAHH and SAMS genes of pear have relatively high expression patterns in flowers and stems, except for PbCGS1. RNA-seq and qRT-PCR combined analysis showed that PbSAMS1 may be involved in the regulation of pear stone cell development. In summary, this study provides the basic information of CGS, SAHH and SAMS genes in five Rosaceae species, further revealing the expression patterns in the pear fruit, which provides the theoretical basis for the regulation of pear stone cells.
«КОРОЛИ АРКЕБУЗЫ» И «РЫЦАРИ ПРИСЯГИ» В ПРОВЕНЕ ВРЕМЕН РЕЛИГИОЗНЫХ ВОЙН, "Средние века"
Authors: Уваров П.Ю.
Published: March 2022

На рубеже Средних веков и раннего Нового времени на Западе существовали разнообразные рекреативные корпорации, среди которых были и стрелковые сообщества в форме братств, «аббатств» или «королевств». Их деятельность в Эльзасе, Фландрии, Швейцарии, Германии и Ливонии изучена неплохо, чего нельзя сказать о подобных объединениях в городах Франции. «Мемуары» Клода Атона проливают свет на деятельность «королевства Аркебузы и рыцарей Присяги», созданного с разрешения короля для организации стрелковых состязаний в Провене. Ежегодные парады «рыцарей аркебузной Присяги» и последующие стрельбы, призванные выявить нового «короля Аркебузы», как и периодические встречи с «королевствами» других городов, были важными событиями в городской жизни. В Провене существовали похожие объединения и для состязаний в стрельбе из арбалета (бюджет арбалетчиков был более скромным, чем у аркебузиров), и для игры в мяч. «Рыцарями аркебузной Присяги» и «игроками в мяч», выезжавшими на состязание в другие города, зачастую были одни и те же люди. Речь шла о своеобразных престижных клубах. Но в них могли воспроизводиться социальные коллизии, характерные для муниципальной элиты французских городов во время Религиозных войн.
ПАМЯТИ БОРИСА ЛЬВОВИЧА ФОНКИЧА (1938–2021), "Средние века"
Authors: Бибиков М.В.
Published: March 2022

2 сентября 2021 г. ушел из жизни Борис Львович Фонкич – выдающийся специалист по греческой палеографии и кодикологии, автор многочисленных открытий в области изучения византийской и поствизантийской рукописной книги, идентификатор таких дуктов и местных видов письма, как иерусалимский и южноитальянский, исследователь индивидуальных почерков греческих книжников, пионер выявления на основе рукописного материала начала и эволюции греческого книгописания в России, исследователь отечественных и зарубежных собраний греческих рукописей, их собирателей и исследователей и т.д.
Stress self-perception and burnout in chiropractic students in a lockdown situation due to COVID-19: A cross-sectional and comparative study
Authors: Etxeberria Irati Rodriguez , de la Ossa Pablo Pérez , Rank Maike Perelló
Published: March 2022

Objective

The purpose of this study was to investigate if COVID-19 lockdown affected stress-perception and burnout in chiropractic students from our institution.

Methods

Stress and burnout in students were assessed using the Perceived Stress Scale and the Maslach Burnout Inventory. The surveys were sent out electronically in March 2020 to chiropractic students enrolled at our college. Data were analyzed with descriptive statistics and t test or analysis of variance to determine statistically significant differences between variables. Data were compared with that obtained in 2018, under no lockdown conditions.

Results

The survey had an overall response rate of 48.94%. Women presented statistically significant higher values for stress (p = .002) and exhaustion (p = .007). Younger students tended to suffer more stress than their older peers. When comparing lockdown data with that of 2018, students presented significantly lower stress levels but higher cynicism.

Conclusion

Women presented higher values for stress and exhaustion than the men. When comparing data with a prior study in 2018 with no lockdown situation, current students appeared to have lower levels of stress but increased cynicism.
Cause‐Specific Mortality in Patients With Gout in the US Veterans Health Administration: A Matched Cohort Study
Authors: Helget Lindsay N. , England Bryant R. , Roul Punyasha , Sayles Harlan , Petro Alison D. , Neogi Tuhina , O'Dell James R. , Mikuls Ted R.
Published: March 2022

Objective

To compare all‐cause and cause‐specific mortality risk between patients with gout and patients without gout in the Veteran's Health Administration (VHA).

Methods

We performed a matched cohort study, identifying patients with gout in the VHA from January 1999 to September 2015 based on the presence of ≥2 International Classification of Diseases, Ninth Revision codes for gout (274.X). Gout patients were matched up to 1:10 on birth year, sex, and year of VHA enrollment with patients without gout and followed until death or end of study (December 2017). Cause of death was obtained from the National Death Index. Associations of gout with all‐cause and cause‐specific mortality were examined using multivariable Cox regression.

Results

Gout (n = 559,243) and matched non‐gout controls (n = 5,428,760) had a mean age of 67 years and were 99% male. There were 246,291 deaths over 4,250,371 patient‐years in gout patients and 2,000,000 deaths over 40,441,353 patient‐years of follow‐up in controls. After matching, gout patients had an increased risk of death (hazard ratio [HR] 1.09 [95% confidence interval (95% CI) 1.08–1.09]), which was no longer present after adjusting for comorbidities (HR 0.98 [95% CI 0.97–0.98]). The strongest association of gout with cause‐specific mortality was observed with genitourinary conditions (HR 1.50 [95% CI 1.47–1.54]). Gout patients were at lower risk of death related to neurologic (e.g., Alzheimer's disease and Parkinson's disease) (HR 0.63 [95% CI 0.62–0.65]) and mental health (HR 0.66 [95% CI 0.65–0.68]) conditions.

Conclusion

A higher risk of death among gout patients in the VHA was related to comorbidity burden. While deaths attributable to neurologic and mental health conditions were less frequent among gout patients, genitourinary conditions were the most overrepresented causes of death.
Test–Retest Reliability and Sensitivity to Change of Ultrasound‐Based Methods of Measuring Synovial Inflammation in Knee Osteoarthritis
Authors: Philpott Holly T. , Birmingham Trevor B. , Dima Robert , Pinto Ryan , Bryant Dianne , Appleton C. Thomas
Published: March 2022

Objectives

To assess test–retest reliability of musculoskeletal ultrasound (US) measures of inflammation in patients with knee osteoarthritis (OA) and to assess the sensitivity to change of US measures of inflammation in patients with knee OA.

Methods

To mimic a common clinical scenario, 36 patients (n = 70 knees) with symptomatic knee OA who were in stable condition underwent 2 assessments within 14 days by different operators and different US machines, graded by a single rater. Test–retest reliability was measured using Cohen's kappa coefficient, intraclass correlation coefficient (ICC), and absolute agreement parameters. A total of 51 patients (n = 72 knees) were tested immediately before and 21–28 days after intraarticular glucocorticoid injection to investigate sensitivity to change and longitudinal construct validity. Paired t‐tests and standardized response mean (SRM) were used to assess sensitivity to change. Multivariate linear regression was used to investigate longitudinal construct validity of US with Knee Injury and Osteoarthritis Outcome Score (KOOS) pain scores, while adjusting for covariates.

Results

US measures of inflammation demonstrated moderate (κ = 0.41, 0.60) to substantial (κ = 0.61, 0.80) agreement. Quantitative measures of synovitis and effusion demonstrated good test–retest reliability (ICC2,1 0.71, 0.92). US measures of synovitis and effusion demonstrated low‐to‐moderate sensitivity to change (SRM –0.29, –0.50). The associations between changes in US measures and KOOS pain scores over time were low, and 95% confidence intervals included zero.

Conclusion

In a clinical setting, US measures of inflammatory features of knee OA have substantial reliability and low‐to‐moderate sensitivity to change, whereas measures of structural OA features are less reliable. Longitudinal construct validity of US measures of synovitis and effusion to KOOS pain scores is not strongly supported.
Postoperative Major Adverse Cardiac Events in Patients With Systemic Lupus Erythematosus
Authors: Bruera Sebastian , Lei Xiudong , Blau Brandon , Zhao Hui , Deswal Anita , Yazdany Jinoos , Giordano Sharon H. , Suarez‐Almazor Maria E.
Published: March 2022

Objectives

Patients with systemic lupus erythematosus (SLE) have a high risk of cardiovascular disease that could potentially increase postoperative major adverse cardiac events (MACE). We determined the rate of MACE in patients with SLE undergoing noncardiac surgery using national claims‐based data.

Methods

This was a retrospective cohort study using Optum Clinformatics Data Mart from 2007 to 2020. We identified a cohort of patients with SLE who had undergone noncardiac surgeries using Current Procedural Terminology codes. We also identified two control cohorts without SLE, one with diabetes mellitus (DM) and one without DM. After matching cases and controls by age and sex, the odds of MACE were estimated using multivariable logistic regression models also including race and the Revised Cardiac Risk Index (RCRI) scores. We also examined use of preoperative cardiac testing.

Results

We identified 4750 patients with SLE, 496,381 DM controls, and 1,484,986 non‐DM controls. After matching, the odds ratio (OR) for MACE in patients with SLE versus non‐DM controls was 1.51 (95% confidence interval 1.09‐2.08), which decreased after adjustment for RCRI score (OR: 0.97, 95% confidence interval 0.7‐1.36). No significant differences were observed in the incidence of MACE between patients with SLE and DM controls (0.82 vs 1.04, P = 0.16). High‐risk patients with SLE (RCRI score of ≥3) were less likely to receive preoperative cardiac testing than non‐DM controls (42.7% vs 35.1%, P < 0.05).

Conclusion

Patients with SLE have an increased risk of postoperative MACE, which is driven by increased RCRI scores. Concerningly, high‐risk patients received less cardiac testing 2 months before surgery than non‐DM controls.
Layer‐by‐Layer Processed PM6:Y6‐Based Stable Ternary Polymer Solar Cells with Improved Efficiency over 18% by Incorporating an Asymmetric Thieno[3,2‐b]indole‐Based Acceptor
Authors: Chen Jinglong , Cao Jiamin , Liu Longfei , Xie Liang , Zhou Hu , Zhang Jianqi , Zhang Kai , Xiao Manjun , Huang Fei
Published: March 2022

Although much research on device engineering have brought about significant improvements in PM6:Y6‐based polymer solar cell (PSCs) performance, there is still a lack of relevant research to solve the problems caused by the over‐aggregation of Y6 and the long‐term stability of the device morphology. Herein, a newly designed and synthesized low‐bandgap asymmetric small molecule acceptor TIT‐2Cl based on thieno[3,2‐b]indole core is elaborately introduced into PM6:Y6‐based PSCs to suppress the over‐aggregation of Y6 molecules with significantly increased efficiency from 15.78% to 17.00%. Moreover, the addition of TIT‐2Cl contributes to improved light harvesting, the lowest unoccupied molecular orbital level of Y6:TIT‐2Cl, charge separation, transport, and extraction. Simultaneously, the PSCs are further prepared by using the progressive spin‐coating method of layer‐by‐layer (LBL). Due to the formation of vertical phase distribution and the improvement of carrier transport performance, the champion efficiency of LBL‐type ternary PSCs reaches 18.18%, which is the highest efficiency reported for PM6:Y6‐based PSCs, along with superior stability and compositional insensitivity. Therefore, the results show that the combination of ternary strategy by incorporating appropriate asymmetric molecules and the LBL method is an effective means to fabricate highly efficient stable PSCs.
Structural Buffer Engineering on Metal Oxide for Long‐Term Stable Seawater Splitting
Authors: Zhuang Linzhou , Li Jiankun , Wang Keyu , Li Zhiheng , Zhu Minghui , Xu Zhi
Published: March 2022

Seawater electrolysis is an attractive technique for massive green hydrogen production owing to the dominant advantages of seawater resources, namely low‐cost and limitlessness. However, the oxygen evolution reaction (OER) catalysts will be easily deactivated for severe seawater Cl− permeation and corrosion. Herein, a structural buffer engineering strategy is reported to endow the Co2(OH)3Cl with long‐term operation stability and a high OER selectivity of ≈99.6% in seawater splitting. The lattice Cl− of Co2(OH)3Cl can act as the structural buffer, whose continuous leaching during OER can leave vacancies for seawater Cl− invasion, so as to avoid catalyst deactivation. Accordingly, Co2(OH)3Cl can maintain 99.9% of its initial current density after 60 000 s operation, while that of Co(OH)2 decays by 52.7% in 7 000 s. Meanwhile, the lattice Cl− of Co2(OH)3Cl can optimize the binding energy of reaction intermediates on the neighboring OCoO site. Thus, Co2(OH)3Cl exhibits a current density of 330.5 mA cm–2 at the potential of 1.63 V versus RHE, 45.9 times higher than that of Co(OH)2. The structural buffer strategy may be applied to incorporate other metal oxides with suitable anions, and effectively boost their OER activity and stability in alkaline seawater.
Advances in 4D Printed Shape Memory Polymers: From 3D Printing, Smart Excitation, and Response to Applications
Authors: Zhang Jifeng , Yin Zhifu , Ren Luquan , Liu Qingping , Ren Lei , Yang Xue , Zhou Xueli
Published: March 2022

Shape memory polymer (SMP) is a smart material that can revert from a temporary shape to a permanent shape under external stimuli, showing great potential for applications in biomedical, aerospace, and intelligent robotics fields. In recent years, with the in‐depth combination of SMP and 4D printing, many breakthroughs have been made in smart manufacturing and multifunctional integrated response. Here, the authors overview the research progress of 4D printing SMP, focusing on the diverse excitation methods, intelligent response deformation modes, and applications of 4D printing SMP. Finally, they point out the problems and future development directions of 4D printing SMP in terms of the printing process, SMP modification, structural design, and multifunctional coupling design.
Stretchable and Flexible Non‐Enzymatic Glucose Sensor Based on Poly(ether sulfone)‐Derived Laser‐Induced Graphene for Wearable Skin Diagnostics
Authors: Luo Yu , Zhu Bicheng , Zhang Shuyuan , Zhang Peikai , Li Xiang , Wang Li , Lu Bingheng , Travas‐Sejdic Jadranka
Published: March 2022

The laser‐induced graphene (LIG) has a great potential in electrochemically active electrodes for wearable biosensors. Herein, for the first time, a stretchable and non‐enzymatic glucose sensor based on LIG derived from commercial poly(ether sulfone) (PES) membranes is reported. The LIG is in situ transferred onto an elastomer and tightly wrapped by the elastomer in one laser carbonization step. Superior to the conventional casting and demolding transfer process, this method avoids the LIG's morphology distortion and loss. By adjusting the laser settings and the patterns, hierarchically structured electrodes are prepared with greatly increased surface areas for glucose detection. The electrodeposited dendritic gold‐nanoparticles act as the catalyst for glucose sensing. The optimized flexible sensor demonstrates a linear range for glucose from 10 μm to 10.0 mm and a detection limit of 26 μm. The sensor shows a sensitivity of 0.024 ± 0.001 mA mm−1 and selectivity toward other interfering metabolites, as well as excellent performance under mechanical bending (stable performance after 500 bending cycles) and stretchability (resistance unchanged after 1000 cyclic stretching at 20% strain). Due to the simplicity of preparation and extraordinary fidelity, the novel PES‐LIG sensor is a promising candidate for the next generation of skin‐adherent diagnostic devices and wearable electronics.
Remarkable Activity of 002 Facet of Ruthenium Nanoparticles Grown on Graphene Films on the Photocatalytic CO2 Methanation
Authors: Anouar Aicha , García‐Aboal Rocío , Atienzar Pedro , Franconetti Antonio , Katir Nadia , El Kadib Abdelkrim , Primo Ana , Garcia Hermenegildo
Published: March 2022

In the context of diminishing atmospheric CO2 emissions, there is an urgent need to develop processes that can be carried out at a scale commensurate with appropriate CO2 volumes. One possible reaction is the transformation of CO2 to methane (Sabatier reaction). Due to its chemical stability, catalytic CO2 hydrogenation to methane is carried out at temperatures of 450 °C or higher and pressures above 5 bars, thus, requiring a significant energy input. One alternative possibility to conventional thermal catalysis is the use of solar light as the primary energy, performing the photocatalytic CO2 hydrogenation. In this broad context, the present study shows the photocatalytic activity of nanometric films of oriented Ru nanoparticles (NPs) strongly grafted on defective graphene. These graphene films (thinner than 20 nm) containing Ru NPs nanoplatelets (less than 2 nanomolRu/cm2) are among the most active photocatalysts ever prepared for CO2 hydrogenation and operate through photoinduced charge separation.
CdIn2S4‐xSex Solid‐Solution Nanocrystal Photocatalyst: One‐Step Hydrothermal Synthesis, Controllable Band Structure, and Improved H2‐Evolution Activity
Authors: Li Zhiwei , Zhong Wei , Gao Duoduo , Chen Feng , Yu Huogen
Published: March 2022

Metal sulfide solid‐solutions have served as one of the most promising photocatalysts due to continuously adjustable bandgap structure and light‐absorption performance. Herein, a novel quaternary CdIn2S4‐xSex solid‐solution nanocrystal photocatalyst is prepared by one‐step hydrothermal synthesis, including the initial production of CdIn2S4‐x(SeO3)x and its in situ reduction of SeO32− to produce Se2− by N2H4. It is found that the bandgap structure of CdIn2S4‐xSex nanocrystals can be adjusted from 2.42 to 1.87 eV by varying the molar ratio of Se/S. Compared with pure CdIn2S4, the CdIn2S4‐xSex solid‐solution photocatalyst clearly represents excellent photocatalytic hydrogen production performance, while the CdIn2S4‐xSex (x = 0.4) solid‐solution nanocrystal exhibits the optimal hydrogen‐production efficiency of 314.24 µmol h−1, which is 3.3 times superior to that of CdIn2S4 (94.83 µmol h−1). It is found that the introduction of Se increases the charge density of S2− to form electron‐enriched S(2+δ )−, which can promote the effective adsorption of H+ for the following interfacial hydrogen‐evolution reaction. Meanwhile, the CdIn2S4‐xSex solid‐solution nanocrystals have a higher conduction band and stronger visible‐light absorption ability, which is also essential for accelerating photocatalytic hydrogen‐production efficiency. This study may offer possibilities for developing high‐performance photocatalysts.
Preparation and characterization of polyvinyl alcohol/polylactic acid/titanium dioxide nanocomposite films enhanced by γ‐irradiation and its antibacterial activity
Authors: Ali Hussein E. , Elbarbary Ahmed M. , Abdel‐Ghaffar Ashraf M. , Maziad Nabila A.
Published: March 2022

Synthesis of antimicrobial films for packaging applications is eminent fields of research. This study describes preparation of biodegradable Poly (PVA/PLA/TiO2) nanocomposite films was carried out by blending polyvinyl alcohol (PVA) and polylactic acid (PLA) doped with titanium dioxide (TiO2) nanoparticles using solution casting method and then irradiated by γ‐irradiation. The properties of the films were characterized by FT‐IR, XRD, FE‐SEM, TEM, TGA, and mechanical tests. The addition of TiO2 nanoparticles (0.8 wt%) explored considerable effects on thermal stability of the films. Results of FE‐SEM and TEM illustrated quite uniformly dispersion of TiO2 nanoparticles with average size of 17.5 nm. The effect of γ‐irradiation on nanocomposite films showed enhanced water resistance property and water vapor transmission rate. The water resistance property was achieved using PVA/PLA composition ratio (2/1). The antibacterial activity was evaluated against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) bacteria. Poly(PVA/PLA/TiO2) nanocomposite film irradiated at 20 kGy displayed improved antibacterial activity and was selected for soil burial biodegradation tests. The biodegradation rate increased rapidly in the initial 12 weeks with significant changed morphology. The enhanced antibacterial efficiency and biodegradation property of the nanocomposite films suggest their possible use for development of packaging materials with low environmental impact.
Die Kampmannbrücke über die Ruhr in Essen
Authors: Keil Andreas , Linden Sebastian , Weber Jakob
Published: March 2022

Die neue Kampmannbrücke über die Ruhr verbindet die Essener Stadtteile Heisingen und Kupferdreh und dient als Ersatz für eine Stahlbeton‐Verbundbrücke aus den 1950er‐Jahren, die aufgrund fortschreitender Korrosionsschäden abgerissen werden musste. Die neue Hauptbrücke ist als einhüftige, selbstverankerte Schrägseilbrücke mit Verbundfahrbahnplatte ausgeführt. Die bestehenden Stützen und Pfahljoche der alten Brücke konnten als Auflager für ein Traggerüst zur Herstellung der Stahlkonstruktion und des Seiltragwerks verwendet werden, wodurch eine aufwendigere Herstellung im Freivorbau vermieden wurde. Entstanden ist ein ingenieurtechnisch prägnantes und wirtschaftliches Bauwerk, das sich elegant in das umliegende Naturschutzgebiet einfügt. Das liegt auch an der Entwicklung eines innovativen Spannverfahrens, das es ermöglichte, die Seilverankerungen besonders kompakt zu entwerfen. Dadurch treten diese am Brückendeck in den Hintergrund und bieten einen freien Blick auf die Ruhr und den Baldeneysee.