bluuebunny/crossref_metadata_2025 huggingface dataset:
The Corrosion Resistance of Reinforced Reactive Powder Concrete with Secondary Aluminum Ash Exposed to NaCl Action
Authors: Jiang Hong , Wang Kewei , Wang Hui
Published: August 2023

Secondary aluminum ash (SAA) is a type of common solid waste which leads to pollution without treatment. Due to its chemical reactivity, the application of SAA to reactive powder concrete (RPC) may help solidify this solid waste while increasing its performance. However, RPC is usually in active service when used with steel bars. NaCl can corrode the steel bars when reinforced RPC is used in a coastal environment. In this study, the corrosion resistance of reinforced RPC was investigated. The specimens were exposed to an environment of NaCl with freeze–thaw cycles (F-Cs) and dry–wet alternations (D-As). The corresponding mass loss rates (MRs), the electrochemical impedance spectroscopy (EIS) curves and the dynamic modulus of elasticity (DME) were measured. The results show that the MR and the DME of reinforced RPC decrease with increasing values of F-C and D-A. F-C and D-A increases lead to increased electrical resistance (R). The real part value corresponding to the extreme point of the EIS curve is increased by 0~213.7% when the SAA is added. The relationship between the imaginary part and the real part of the EIS fits the quadratic function. The equivalent circuit of the reinforced RPC is obtained from the EIS curves. The R of the rust is calculated by using the equivalent circuit. The rust’s R decreases in the quadratic function with the mass ratio of the SAA. After 200 NaCl F-Cs, the MR, the DME and the R vary within the ranges of 23.4~113.6%, −2.93~−4.76% and 4.92~13.55%. When 20 NaCl D-As are finished, the MR, the DME and the R vary within the ranges of 34.7~202.8%, −13.21~−14.93% and 120.48~486.39%. The corrosion area rates are 2.3~68.7% and 28.7~125.6% higher after exposure to 200 NaCl F-Cs and 20 NaCl D-As. When the SAA is mixed, the MR is decreased by 0~13.12%, the DME increases by 0~3.11%, the R of the reinforced RPC increases by 26.01~152.43% and the corrosion area rates are decreased by 21.39~58.62%. This study will provide a novel method for solidifying SAA while improving the chlorine salt resistance of RPC.
No Blood Loss Increase in Cementless vs. Cemented Fixation Following Bilateral Total Knee Arthroplasty: A Propensity Score Matching Study
Authors: Sohn Sueen , Cho Nicole , Oh Hyunjoo , Kim Yong Deok , Jo Hoon , Koh In Jun
Published: August 2023

Background and Objectives: Recent advancements in three-dimensional printing technology have enhanced the biologic fixation of cementless total knee arthroplasty (TKA), therefore increasing the utilization of newer-generation cementless implants. However, the lack of sealing and tamponade effect of cement on the resected bone surface after cementless TKA raises concerns regarding the potential for greater blood loss compared to cemented TKA. The aim of this study was to (1) compare blood loss and transfusion rates between cementless and cemented TKAs and (2) identify the risk factor for higher blood loss in patients who underwent 1-week-interval staggered bilateral (SB) TKA. Materials and Methods: This retrospective, propensity-matched study included 54 cementless and 53 cemented SB TKAs performed by a single surgeon from 2019 to 2023 with a single implant that has similar design features in both cementless and cemented implants. All patients underwent 1-week-interval SB TKA and received the same patient blood management (PBM) and rehabilitation protocol. The estimated total blood loss (TBL), transfusion rate, and total hemoglobin drop were assessed. Patients were categorized according to TBL into average TBL and higher TBL groups. Univariate and multiple logistic regression analyses were performed to identify risk factors for higher blood loss. Results: There was no difference in TBL between cementless and cemented TKA groups (1233 ± 299 and 1282 ± 309 mL, respectively; p > 0.05). In addition, no between-group differences in the transfusion rate and mean total hemoglobin drop were observed. The logistic regression analyses revealed that whether TKA was cementless or cemented was not associated with higher blood loss; rather, the only identified risk factor was the pre-TKA patient blood volume (odd ratio 1.001, 95% confidence interval 1.000–1002, p = 0.026). Conclusions: Contemporary cementless fixation does not increase blood loss or transfusion rates compared to cemented fixation in patients undergoing 1-week-interval staggered bilateral TKA.
Study on ZrSi2 as a Candidate Material for Extreme Ultraviolet Pellicles
Authors: Wi Seong Ju , Kim Won Jin , Kim Haneul , Jeong Dongmin , Lee Dong Gi , Choi Jaehyuck , Cho Sang Jin , Yu Lan , Ahn Jinho
Published: August 2023

An extreme ultraviolet (EUV) pellicle is an ultrathin membrane at a stand-off distance from the reticle surface that protects the EUV mask from contamination during the exposure process. EUV pellicles must exhibit high EUV transmittance, low EUV reflectivity, and superior thermomechanical durability that can withstand the gradually increasing EUV source power. This study proposes an optimal range of optical constants to satisfy the EUV pellicle requirements based on the optical simulation results. Based on this, zirconium disilicide (ZrSi2), which is expected to satisfy the optical and thermomechanical requirements, was selected as the EUV pellicle candidate material. An EUV pellicle composite comprising a ZrSi2 thin film deposited via co-sputtering was fabricated, and its thermal, optical, and mechanical properties were evaluated. The emissivity increased with an increase in the thickness of the ZrSi2 thin film. The measured EUV transmittance (92.7%) and reflectivity (0.033%) of the fabricated pellicle satisfied the EUV pellicle requirements. The ultimate tensile strength of the pellicle was 3.5 GPa. Thus, the applicability of the ZrSi2 thin film as an EUV pellicle material was verified.
Mechanical Properties of Double-Layer Riveted Aluminum Roofing Panels with Curved Surfaces
Authors: Yuan Ye , Zhang Qilin , Luo Xiaoqun , Yuan Lin , Zhang Shaoquan , Ge Hanbin
Published: August 2023

In recent years, aluminum alloy has been increasingly used in building structures, becoming an important construction material for metal structures. Currently, aluminum alloy is commonly used in buildings as beam–column components, profiled roof panels, and door and window frames, among other forms. However, there is limited research on the mechanical properties of aluminum alloy roof panels with irregular curved surfaces. In this study, a full-scale curved double-layer anisotropic riveted aluminum alloy roof panel was subjected to a load test to analyze its deformation patterns and failure mechanisms. The results indicate that the load-bearing capacity of the roof panel meets the design requirements. During failure, neither the upper nor lower layers of the panel enter the plastic deformation stage, indicating sufficient safety redundancy. The failure mode observed is a ductile failure with noticeable deformation with the weak points of the component being the riveted connections of the stiffeners. A finite element model was established for numerical simulation and the results matched well with the experimental data. Finally, a theoretical calculation for the ultimate load-bearing capacity of the roof panel was derived, providing a reference for design purposes.
Study of Bearing Capacity of Aluminum Alloy Thin-Walled Circular Tube Filled with Lightweight Filler
Authors: Zhang Zheng , Wang Qian , Hu Meng , Guo Xiaonong
Published: August 2023

In this study, experimental research, a numerical simulation, and a theoretical analysis were performed on the bearing capacity of an aluminum alloy circular tube filled with a lightweight filler (ATLF). Bearing capacity tests were conducted for six ATLF columns and two aluminum alloy hollow tubes (AAHTs), and their local buckling failure modes and mechanical properties were obtained. A finite element model was developed using ABAQUS software (ABAQUS 2016, ABAQUS Inc., Palo Alto, CA, USA) for numerical calculations. Furthermore, a large-scale numerical analysis was performed to investigate the effect of structural parameters, such as the tube thickness, diameter, column length, and initial geometric imperfections, as well as the aluminum alloy’s properties and the lightweight filler’s properties, on the bearing capacity of the ATLF columns and AAHTs under axial compression. Based on the test and numerical analysis results, a formula for calculating the local buckling stress of AAHTs under axial compression is proposed. An improved coefficient of bearing capacity for the ATLF columns caused by the internal lightweight filler was obtained by fitting, and based on the results, a formula for computing the bearing capacity of ATLF columns under axial compression is proposed in this study.
On the Use of Machine Learning Algorithms to Predict the Corrosion Behavior of Stainless Steels in Lactic Acid
Authors: Pourrahimi Shamim , Hakimian Soroosh , Bouzid Abdel-Hakim , Hof Lucas A.
Published: August 2023

Predicting the corrosion behavior of materials in specific environmental conditions is important for establishing a sustainable manufacturing system while reducing the need for time-consuming experimental investigations. Recent studies started to explore the application of supervised Machine Learning (ML) techniques to forecast corrosion behavior in various conditions. However, there is currently a research gap in utilizing classification ML techniques specifically for predicting the corrosion behavior of stainless steel (SS) material in lactic acid-based environments, which are extensively used in the pharmaceutical and food industry. This study presents a ML-based prediction model for corrosion behavior of SSs in different lactic acid environmental conditions, using a database that described the corrosion behavior by qualitative labels. Decision tree (DT), random forest (RF) and support vector machine (SVM) algorithms were applied for classification. Training and testing accuracies of, respectively 97.5% and 92.5% were achieved using the DT classifier. Four SS alloy composition elements (C, Cr, Ni, Mo), acid concentration, and temperature were found sufficient to consider as input data for corrosion prediction. The developed models are reliable for predicting corrosion degradation and, as such, contribute to avoiding failures and catastrophes in industry.
FEM Simulation on First-Step Drawing Process of Platinum-Clad Nickel Bars
Authors: Chen Yongtai , Yang Mingxiang , Hu Jieqiong , Zhang Jiming , Yang Youcai , Xie Ming
Published: August 2023

The purpose of this study is to investigate the effects of semi-angle and platinum tube wall thicknesses on the first-step drawing process of platinum-clad nickel bars using finite element simulation. Three different semi-angles of die (3°, 5°, 7°) and three different platinum tube wall thicknesses (0.275 mm, 0.3 mm, 0.325 mm) were selected in the study. The effects of semi-angle and platinum tube wall thicknesses on drawing force, equivalent stress, cladding behavior and damage coefficients during the first-step drawing process were discussed in detail. The simulated results of cladding condition and damage obtained from Deform 3D V11 software are validated with experimental results, and it was found that the results were in good agreement. The results of this study may provide a reference for the practical production of platinum-clad nickel wires.
Effects of ErF3 Particles on the Structure and Physicomechanical Properties of A359 Alloy
Authors: Kakhidze Nikolai , Valikhov Vladimir , Selikhovkin Mikhail , Khrustalyov Anton , Zhukov Ilya , Vasiliev Sergey , Vorozhtsov Alexander
Published: August 2023

In this work, the impact of ErF3 submicroparticles on the microstructure and mechanical properties of the A359 alloy was studied. ErF3 particles provided a homogeneous structure in castings produced via the casting method. The modifying effect of ErF3 particles on the structure of Al–Si alloys is realized through the mechanism of restraining the crystallization front and is achieved through the reduction in the formation of clusters of iron phases and eutectic lamellar silicon. It was found that the addition of 1 wt% ErF3 to the A359 alloy leads to a decrease in the average grain size by 21% and an increase in the yield strength by 14%, in tensile strength by 16%, in the microhardness of Al15(FeMn)3Si2 phase by 34% and in the Al15(FeMnCr)3Si2 phase by 7%. The heat treatment of the A359 alloy with ErF3 particles increased the yield strength by 36% and the tensile strength by 34%. The absence of an effect of ErF3 particles on the hardness values of the A359 alloy, as well as on the fracture process of the A359 alloy, was observed. The negative influence of ErF3 particle agglomerates and clusters on the strength characteristics of the investigated alloys was observed. Approaches for further exploring the potential of ErF3 particles as a strengthening phase in cast aluminum alloys of the Al–Si system were proposed.
Deciphering Molecular Aspects of Potential α-Glucosidase Inhibitors within Aspergillus terreus: A Computational Odyssey of Molecular Docking-Coupled Dynamics Simulations and Pharmacokinetic Profiling
Authors: Elhady Sameh S. , Alshobaki Noha M. , Elfaky Mahmoud A. , Koshak Abdulrahman E. , Alharbi Majed , Abdelhameed Reda F. A. , Darwish Khaled M.
Published: August 2023

Hyperglycemia, as a hallmark of the metabolic malady diabetes mellitus, has been an overwhelming healthcare burden owing to its high rates of comorbidity and mortality, as well as prospective complications affecting different body organs. Available therapeutic agents, with α-glucosidase inhibitors as one of their cornerstone arsenal, control stages of broad glycemia while showing definitive characteristics related to their low clinical efficiency and off-target complications. This has propelled the academia and industrial section into discovering novel and safer candidates. Herein, we provided a thorough computational exploration of identifying candidates from the marine-derived Aspergillus terreus isolates. Combined structural- and ligand-based approaches using a chemical library of 275 metabolites were adopted for pinpointing promising α-glucosidase inhibitors, as well as providing guiding insights for further lead optimization and development. Structure-based virtual screening through escalating precision molecular docking protocol at the α-glucosidase canonical pocket identified 11 promising top-docked hits, with several being superior to the market drug reference, acarbose. Comprehensive ligand-based investigations of these hits’ pharmacokinetics ADME profiles, physiochemical characterizations, and obedience to the gold standard Lipinski’s rule of five, as well as toxicity and mutagenicity profiling, proceeded. Under explicit conditions, a molecular dynamics simulation identified the top-stable metabolites: butyrolactone VI (SK-44), aspulvinone E (SK-55), butyrolactone I 4′’’’-sulfate (SK-72), and terrelumamide B (SK-173). They depicted the highest free binding energies and steadiest thermodynamic behavior. Moreover, great structural insights have been revealed, including the advent of an aromatic scaffold-based interaction for ligand–target complex stability. The significance of introducing balanced hydrophobic/polar moieties, like triazole and other bioisosteres of carboxylic acid, has been highlighted across docking, ADME/Tox profiling, and molecular dynamics studies for maximizing binding interactions while assuring safety and optimal pharmacokinetics for targeting the intestinal-localized α-glucosidase enzyme. Overall, this study provided valuable starting points for developing new α-glucosidase inhibitors based on nature-derived unique scaffolds, as well as guidance for prospective lead optimization and development within future pre-clinical and clinical investigations.
Impact of Heavy Metal Exposure on Mytilus galloprovincialis Spermatozoa: A Metabolomic Investigation
Authors: Lettieri Gennaro , Marinaro Carmela , Notariale Rosaria , Perrone Pasquale , Lombardi Martina , Trotta Alessio , Troisi Jacopo , Piscopo Marina
Published: August 2023

Metabolomics is a method that provides an overview of the physiological and cellular state of a specific organism or tissue. This method is particularly useful for studying the influence the environment can have on organisms, especially those used as bio-indicators, e.g., Mytilus galloprovincialis. Nevertheless, a scarcity of data on the complete metabolic baseline of mussel tissues still exists, but more importantly, the effect of mussel exposure to certain heavy metals on spermatozoa is unknown, also considering that, in recent years, the reproductive system has proved to be very sensitive to the effects of environmental pollutants. In order to fill this knowledge gap, the similarities and differences in the metabolic profile of spermatozoa of mussels exposed to metallic chlorides of copper, nickel, and cadmium, and to the mixture to these metals, were studied using a metabolomics approach based on GC–MS analysis, and their physiological role was discussed. A total of 237 endogenous metabolites were identified in the spermatozoa of these mussel. The data underwent preprocessing steps and were analyzed using statistical methods such as PLS-DA. The results showed effective class separation and identified key metabolites through the VIP scores. Heatmaps and cluster analysis further evaluated the metabolites. The metabolite-set enrichment analysis revealed complex interactions within metabolic pathways and metabolites, especially involving glucose and central carbon metabolism and oxidative stress metabolism. Overall, the results of this study are useful to better understand how some pollutants can affect the specific physiological functions of the spermatozoa of this mussel, as well as for further GC–MS-based metabolomic health and safety studies of marine bivalves.
Improved Optical Efficiency of 850-nm Infrared Light-Emitting Diode with Reflective Transparent Structure
Authors: Lee Hyung-Joo , Park Jin-Young , Kwac Lee-Ku , Lee Jongsu
Published: August 2023

This study investigated a reflective transparent structure to improve the optical efficiency of 850 nm infrared light-emitting diodes (IR-LEDs), by effectively enhancing the number of extracted photons emitted from the active region. The reflective transparent structure was fabricated by combining transparent epitaxial and reflective bonding structures. The transparent epitaxial structure was grown by the liquid-phase epitaxy method, which efficiently extracted photons emitted from the active area in IR-LEDs, both in the vertical and horizontal directions. Furthermore, a reflective bonding structure was fabricated using an omnidirectional reflector and a eutectic metal, which efficiently reflected the photons emitted downwards from the active area in an upward direction. To evaluate reflective transparent IR-LED efficiency, a conventional absorbing substrate infrared light-emitting diode (AS IR-LED) and a transparent substrate infrared light-emitting diode (TS IR-LED) were fabricated, and their characteristics were analyzed. Based on the power–current (L-I) evaluation results, the output power (212 mW) of the 850 nm IR-LED with the reflective transparent structure increased by 76% and 26%, relative to those of the AS IR-LED (121 mW) and TS IR-LED (169 mW), respectively. Furthermore, the reflective transparent structure possesses both transparent and reflective properties, as confirmed by photometric and radial theta measurements. Therefore, light photons emitted from the active area of the 850 nm IR-LED were efficiently extracted upward and sideways, because of the reflective transparent structure.
Characteristics and Paleoenvironment of High-Quality Shale in the Triassic Yanchang Formation, Southern Margin of the Ordos Basin
Authors: Sun Mengsi , Feng Congjun , Li Yipu
Published: August 2023

A set of high-quality lacustrine shales at the bottom of the Chang 7 member of the Yanchang Formation in the Ordos Basin is one of the main source rocks of tight oil and gas and shale oil in the Yanchang Formation. Based on outcrop, core, drilling and seismic data, by the quantitative characterization of outcrops, fine characterization of logging facies and seismic facies, and geochemical tests, the lithofacies types, geophysical response characteristics and organic geochemical characteristics of this high-quality shale are clarified, and the formation paleoenvironment, including redox conditions, paleoclimate, paleosalinity and paleowater depth, is analyzed. The high-quality shale at the bottom of the Chang 7 member is divided into three lithofacies types: black shale, dark massive mudstone and silty mudstone. The organic matter in black shale is mainly interbedded or stratified, the organic matter in dark massive mudstone is dispersed and the organic matter content in silty mudstone is lower. The shale shows high gamma (more than 260 API), a high acoustic time difference (more than 280 μs/m), a high resistivity (more than 330 Ω m) well-logging phase and strong-amplitude parallel–subparallel seismic phase characteristics. Based on the logging and seismic facies characteristics, the plane distribution range of this set of shales is defined. The sedimentary thickness gradually increases from the edge (5–10 m) to the center of the basin, among which the Jiyuan–Huachi–Yijun black shale has the largest thickness (more than 30 m). This set of high-quality shales was mainly formed under a warm and humid paleoclimate, in water depths of 60–120 m, and in an anaerobic reducing and continental freshwater paleoenvironment. The fine identification, distribution range and formation conditions of black shale lithofacies are of practical significance for predicting the distribution of favorable lithofacies of shale oil and gas and the deployment of horizontal wells.
The Behavior of Rare Earth Elements during Green Clay Authigenesis on the Congo Continental Shelf
Authors: Bayon Germain , Giresse Pierre , Chen Hongjin , Rouget Marie-Laure , Gueguen Bleuenn , Moizinho Gabriel Ribeiro , Barrat Jean-Alix , Beaufort Daniel
Published: August 2023

Clay mineral authigenesis at continental margins plays an important role in global marine element cycles. However, despite being increasingly used as tracers for both modern and past oceanographic conditions, the behavior of the rare earth elements (REEs) and their isotopes during marine clay authigenesis still remains poorly known. In this study, we report on a detailed geochemical investigation of glauconite from the West African continental shelf, near the mouth of the Congo River. Elemental, neodymium, and hafnium isotope analyses were conducted on both acid leachate and separated clay-size fractions of glauconite pellets, in order to investigate the behavior of REE during the formation of authigenic clays. Our data indicate that kaolinite dissolution and subsequent Fe-bearing clay authigenesis act as a net source of REEs to seawater. We show that enhanced glauconitization, as inferred from increasing Fe and K contents, is accompanied by significant decoupling of the REE toward markedly LREE-enriched shale-normalized patterns in neoformed clay separates. Using both Nd and Hf isotopes and SEM observations, we rule out any seawater influence and argue that this shift primarily reflects the progressively overwhelming presence of insoluble nanocrystals of detrital LREE-rich phosphates, which are known to occur in close association with kaolinite in tropical soils. Due to their marked insolubility in surface environments, such nanocrystals can be preserved during kaolinite dissolution and subsequently incorporated into the aggregates of authigenic green clays forming the peloids. Most strikingly, we show that the combined influence of net REE loss (due to kaolinite dissolution) and decoupling (due to subsequent entrapment of inherited LREE-bearing accessory phases into neoformed clay minerals) is accompanied by preferential release of a dissolved REE fraction characterized by seawater-like distribution patterns. These findings reinforce the emerging view that clay mineral dissolution and authigenesis at continental margins possibly play a major role in marine REE cycling.
Noise Characteristics and Denoising Methods of Long-Offset Transient Electromagnetic Method
Authors: Xu Yang , Xie Xingbing , Zhou Lei , Xi Biao , Yan Liangjun
Published: August 2023

The advantages of the long-offset transient electromagnetic method include deep detection and sensitive response to resistivity anomalies. It is widely used in underground mineral resources exploration, fluid identification in petroleum reservoirs, hydraulic fracturing, and dynamic residual oil and gas monitoring. After the primary field signal is turned off, grounded electrodes or coils are used to observe the secondary eddy field. The secondary field signal decays quickly and has a large dynamic range and a wide frequency band but is easily affected by various natural and human electromagnetic interferences. Therefore, noise reduction and distortion correction are important issues in the processing of transient electromagnetic data. This paper proposes a systematic noise interference suppression process. Multi-period and positive–negative bipolar signal stackings were used to remove random noise and suppress DC offset signals. Then, a time-domain inverse digital recursive method was applied to remove characteristic frequency signals, e.g., power frequency signals and their harmonic interference. A standard noise-free signal was constructed through forward modeling simulation and verified by adding different types of noise. Finally, high-quality transient electromagnetic secondary field attenuation signals were obtained through overlapping windowing technology. We applied this algorithm to obtain electromagnetic data from dynamic monitoring of hydraulic fracturing in Fuling shale gas and from a copper–iron metal mine in Daye City, demonstrating its effectiveness.
Design and Research of a Sound-to-RGB Smart Acoustic Device
Authors: Zlatev Zlatin , Ilieva Julieta , Orozova Daniela , Shivacheva Galya , Angelova Nadezhda
Published: August 2023

This paper presents a device that converts sound wave frequencies into colors to assist people with hearing problems in solving accessibility and communication problems in the hearing-impaired community. The device uses a precise mathematical apparatus and carefully selected hardware to achieve accurate conversion of sound to color, supported by specialized automatic processing software suitable for standardization. Experimental evaluation shows excellent performance for frequencies below 1000 Hz, although limitations are encountered at higher frequencies, requiring further investigation into advanced noise filtering and hardware optimization. The device shows promise for various applications, including education, art, and therapy. The study acknowledges its limitations and suggests future research to generalize the models for converting sound frequencies to color and improving usability for a broader range of hearing impairments. Feedback from the hearing-impaired community will play a critical role in further developing the device for practical use. Overall, this innovative device for converting sound to color represents a significant step toward improving accessibility and communication for people with hearing challenges. Continued research offers the potential to overcome challenges and extend the benefits of the device to a variety of areas, ultimately improving the quality of life for people with hearing impairments.
MWCNTs Decorated with TiO2 as Highly Performing Filler in the Preparation of Nanocomposite Membranes for Scalable Photocatalytic Degradation of Bisphenol A in Water
Authors: Tursi Antonio , Beneduci Amerigo , Nicotera Isabella , Simari Cataldo
Published: August 2023

Bisphenol A (BPA), an endocrine-disrupting compound with estrogenic behavior, is of great concern within the scientific community due to its high production levels and increasing concentration in various surface aquifers. While several materials exhibit excellent capacity for the photocatalytic degradation of BPA, their powdered nature and poor chemical stability render them unsuitable for practical application in large-scale water decontamination. In this study, a new class of nanocomposite membranes based on sulfonated polyethersulfone (sPES) and multiwalled carbon nanotubes decorated with TiO2 nanoparticles (MWCNTs-TiO2) were investigated as efficient and scalable photocatalysts for the photodegradation of BPA in aqueous solutions. The MWCNTs-TiO2 hybrid material was prepared through a facile and inexpensive hydrothermal method and extensively characterized by XRD, Raman, FTIR, BET, and TGA. Meanwhile, nanocomposite membranes at different filler loadings were prepared by a simple casting procedure. Swelling tests and PFG NMR analyses provided insights into the impact of filler introduction on membrane hydrophilicity and water molecular dynamics, whereas the effectiveness of the various photocatalysts in BPA removal was monitored using HPLC. Among the different MWCNTs-TiO2 content nanocomposites, the one at 10 wt% loading (sP-MT10) showed the best photoactivity. Under UV irradiation at 254 nm and 365 nm for 240 min, photocatalytic oxidation of 5 mg/L bisphenol A by sP-MT10 resulted in 91% and 82% degradation, respectively. Both the effect of BPA concentration and the membrane regenerability were evaluated, revealing that the sP-MT10 maintained its maximum BPA removal capability over more than 10 cycles. Our findings indicate that sP-MT nanocomposite membranes are versatile, scalable, efficient, and highly reusable photocatalysts for the degradation of BPA, as well as potentially for other endocrine disruptors.
Novel Nanostructured Scaffolds of Poly(butylene trans-1,4-cyclohexanedicarboxylate)-Based Copolymers with Tailored Hydrophilicity and Stiffness: Implication for Tissue Engineering Modeling
Authors: Guidotti Giulia , Soccio Michelina , Argentati Chiara , Luzi Francesca , Aluigi Annalisa , Torre Luigi , Armentano Ilaria , Emiliani Carla , Morena Francesco , Martino Sabata , Lotti Nadia
Published: August 2023

Here, we present novel biocompatible poly(butylene trans-1,4-cyclohexanedicarboxylate) (PBCE)-based random copolymer nanostructured scaffolds with tailored stiffness and hydrophilicity. The introduction of a butylene diglycolate (BDG) co-unit, containing ether oxygen atoms, along the PBCE chain remarkably improved the hydrophilicity and chain flexibility. The copolymer containing 50 mol% BDG co-units (BDG50) and the parent homopolymer (PBCE) were synthesized and processed as electrospun scaffolds and compression-molded films, added for the sake of comparison. We performed thermal, wettability, and stress–strain measures on the PBCE-derived scaffolds and films. We also conducted biocompatibility studies by evaluating the adhesion and proliferation of multipotent mesenchymal/stromal cells (hBM-MSCs) on each polymeric film and scaffold. We demonstrated that solid-state properties can be tailored by altering sample morphology besides chemical structure. Thus, scaffolds were characterized by a higher hydrophobicity and a lower elastic modulus than the corresponding films. The three-dimensional nanostructure conferred a higher adsorption protein capability to the scaffolds compared to their film counterparts. Finally, the PBCE and BDG50 scaffolds were suitable for the long-term culture of hBM-MSCs. Collectively, the PBCE homopolymer and copolymer are good candidates for tissue engineering applications.
High-Energy Mode-Locked Pulse Er-Doped Fiber Laser-Based GeTe as Saturable Absorber
Authors: Tang Shouqian , Sheng Qiuyan , Ye Faming , Li Qi , Xiong Siyuan , Bai Caixun , Lu Cheng , Zhang Huanian , Wang Guomei , Zhang Wenfei
Published: August 2023

High-energy Er-doped fiber laser with high conversion efficiency is reported, which is mode-locked by a germanium telluride (GeTe)-based saturable absorber (SA). By adjusting the direction of the polarization controller (PC), a high-energy pulse with a central wavelength of 1533.1 nm and a fundamental repetition frequency of 1.58 MHz is achieved. Under the pump power of 450.1 mW, the maximum average output power is 50.48 mW, and the single-pulse energy is 32 nJ. It is worth noting that the optical-to-optical conversion efficiency has reached about 11.2%. The experimental results indicate that GeTe performs excellently as SAs for obtaining mode-locked fiber lasers and plays an extremely important role in high-energy fiber lasers.
Studies on the Functional Properties of Titanium Dioxide Nanoparticles Distributed in Silyl–Alkyl Bridged Polyaniline-Based Nanofluids
Authors: Arumugam Chandravadhana , Velu Nandakumar , Radhakrishnan Padmanaban , Roy Vellaisamy A. L. , Anantha-Iyengar Gopalan , Lee Dong-Eun , Kannan Venkatramanan
Published: August 2023

In the present work, a new kind of nanocomposite (NC)-based solid component was prepared for formulating nanofluids (NFs). The NC comprised metal oxide (titanium dioxide, TiO2) dispersed in a conducting polymer with polyaniline (PANI) and chemically linked silyl–alkyl units in it (PSA) that were designated as T-PSA NC. The NFs with ethylene glycol (EG) as a base fluid were prepared with T-PSA NCs with various compositions of TiO2 and PSA as well for various concentrations of T-PSA NCs. The scanning electron microscopic evaluation of the NC revealed that PSA deposition on TiO2 nanoparticles (NPs) decreased particle agglomeration. The PSA coating on the TiO2 NPs did not influence the crystalline structure of the TiO2 NPs, according to the X-ray diffraction patterns. The thermophysical characterization and molecular interaction features of the NFs at 303 K including a novel inorganic–organic T-PSA NC, were detailed. Furthermore, the stability of the T-PSA NC-based NFs was investigated experimentally using the zeta potential, and the particle size distribution change was analyzed using the dynamic light scattering (DLS) method. The T-PSA NCs had particle sizes that were significantly bigger than pristine PSA and pure TiO2. Most of the preparation conditions used to produce the T-PSA NCs resulted in moderately stable suspensions in EG. The results revealed that the ultrasonic velocity increased with the increase in the concentration of T-PSA NC mass % in the NFs, the refractive index and thermal conductivity increased with the increase in the concentration, and the surface tension exhibited a linear change when the ratio of mass % concentration of the T-PSA NCs increased. The combined presence of components that synergistically contribute to the electro, thermal, optical, and rheological properties is expected to attract advanced applications for NFs.
Graphene-Based Wearable Temperature Sensors: A Review
Authors: Liu Jiajia , Wang Ying , Li Xiangyang , Wang Jiaqi , Zhao Yang
Published: August 2023

Flexible sensing electronics have received extensive attention for their potential applications in wearable human health monitoring and care systems. Given that the normal physiological activities of the human body are primarily based on a relatively constant body temperature, real-time monitoring of body surface temperature using temperature sensors is one of the most intuitive and effective methods to understand physical conditions. With its outstanding electrical, mechanical, and thermal properties, graphene emerges as a promising candidate for the development of flexible and wearable temperature sensors. In this review, the recent progress of graphene-based wearable temperature sensors is summarized, including material preparation, working principle, performance index, classification, and related applications. Finally, the challenges and future research emphasis in this field are put forward. This review provides important guidance for designing novel and intelligent wearable temperature-sensing systems.
VDR, SOD-2, and CYP24A1 Gene Expression in Different Genotypes of BsmI SNP of the Vitamin D Receptor Gene in Individuals with Hypovitaminosis
Authors: Retamoso Vanessa Rosa , Barbisan Fernanda , Moro Graziele Meira , Maurer Patricia , Rubio Débora Vasquez , dos Santos Lauren Flores Viera , Feijóo Lyana Berro , Frizzo Matias Nunes , Mânica da Cruz Ivana Beatrice , Manfredini Vanusa , Barcelos Ana Letícia Vargas , Piccoli Jacqueline da Costa Escobar
Published: August 2023

Background: Hypovitaminosis D is a public health problem due to its implications for various diseases. Vitamin D has numerous functions, such as modulating the metabolism of cellular tissues, and it is expressed through the vitamin D receptor (VDR) gene that may influence gene expression modulation, which plays an important role in vitamin D metabolism. Objective: To evaluate the effect of the genotypes of BsmI single nucleotide polymorphism (SNP) of the VDR gene on VDR, SOD2, and CYP24A1 gene expression in individuals with low serum vitamin D levels. Methods: This was a cross-sectional analytical study. After signing the informed consent form, individuals were invited to participate and answered a structured questionnaire with identification data. Blood was collected for biochemical analysis, and vitamin D was measured by chemiluminescence; BsmI polymorphism was determined using real-time polymerase chain reaction (PCR) assays with TaqMan allelic discrimination, and gene expression was conducted by qRT-PCR using QuantiFast SYBR® Green PCR Master Mix. Data were analyzed using the SPSS 20.0 software, and differences were considered significant at p < 0.05. Results: 98 individuals with vitamin D ≤ 20 ng/dL were evaluated, and the BsmI SNP of the VDR gene showed CYP24A1 overexpression and low SOD2 expression. Conclusion: BsmI SNP of the VDR gene can modulate the expression of the genes evaluated without interfering with serum levels.
Breastfeeding and Inborn Errors of Amino Acid and Protein Metabolism: A Spreadsheet to Calculate Optimal Intake of Human Milk and Disease-Specific Formulas
Authors: Vitoria-Miñana Isidro , Couce María-Luz , González-Lamuño Domingo , García-Peris Mónica , Correcher-Medina Patricia
Published: August 2023

Human milk (HM) offers important nutritional benefits. However, except for phenylketonuria (PKU), there are little data on optimal levels of consumption of HM and a special formula free of disease-related amino acids (SF-AA) in infants with inborn errors of metabolism of amino acids and proteins (IEM-AA-P). We designed a spreadsheet to calculate the amounts of SF-AA and HM required to cover amino acid, protein, and energy needs in patients with the nine main IEM-AA-P in infants aged under 6 months. Upon entering the infant’s weight and the essential amino acid or intact protein requirements for the specific IEM, the spreadsheet calculates the corresponding required volume of HM based on the amino acid concentration in HM. Next, the theoretical daily fluid intake (typical range, 120–200 mL/kg/day) is entered, and the estimated daily fluid intake is calculated. The required daily volume of SF-AA is calculated as the difference between the total fluid intake value and the calculated volume of HM. The spreadsheet allows for the introduction of a range of requirements based on the patient’s metabolic status, and includes the option to calculate the required volume of expressed HM, which may be necessary in certain conditions such as MMA/PA and UCD. In cases in which breastfeeding on demand is feasible, the spreadsheet determines the daily amount of SF-AA divided over 6–8 feeds, assuming that SF-AA is administered first, followed by HM as needed. Intake data calculated by the spreadsheet should be evaluated in conjunction with data from clinical and nutritional analyses, which provide a comprehensive understanding of the patient’s nutritional status and help guide individualized dietary management for the specific IEM.
Evaluation of a New Glycomacropeptide-Based Protein Substitute in Powdered and Liquid Format in Patients with PKU
Authors: Delsoglio Marta , Capener Rebecca , MacDonald Anita , Daly Anne , Ashmore Catherine , Ellerton Charlotte , Donald Sarah , Gaff Lisa , VanDorp Louise , Skeath Rachel , Newby Camille , Dunning Georgina , Dale Clare , Hunjan Inderdip , White Lucy , Allen Heather , Hubbard Gary P. , Stratton Rebecca J.
Published: August 2023

(1) Background: Good adherence to a Phe-restricted diet supplemented with an adequate amount of a protein substitute (PS) is important for good clinical outcomes in PKU. Glycomacropeptide (cGMP)-PSs are innovative, palatable alternatives to amino acid-based PSs (AA-PS). This study aimed to evaluate a new cGMP-PS in liquid and powder formats in PKU. (2) Methods: Children and adults with PKU recruited from eight centres were prescribed at least one serving/day of cGMP-PS for 7–28 days. Adherence, acceptability, and gastrointestinal tolerance were recorded at baseline and the end of the intervention. The blood Phe levels reported as part of routine care during the intervention were recorded. (3) Results: In total, 23 patients (powder group, n = 13; liquid group, n = 10) completed the study. The majority assessed the products to be palatable (77% of powder group; 100% of liquid group) and well tolerated; the adherence to the product prescription was good. A total of 14 patients provided blood Phe results during the intervention, which were within the target therapeutic range for most patients (n = 11) at baseline and during the intervention. (4) Conclusions: These new cGMP-PSs were well accepted and tolerated, and their use did not adversely affect blood Phe control.
Managing Occupational Health Issues through Coaching, Emerging Perspectives from Emergency and Intensive Care Nurses: A Mixed-Method Study
Authors: Chahbounia Rabia , Gantare Abdellah
Published: August 2023

(1) Background: Emergency and intensive care nurses are among the health professionals most exposed to occupational health issues such as stress and burnout, etc. Coaching has been considered a useful preventative strategy to provide better support for professionals. This study has two objectives: the first objective is to identify the coaching needs of emergency and intensive care nurses, and the second is to propose a coaching model that addresses the needs and helps manage occupational health issues. (2) Methods: this study followed a mixed-method design, and it included thirty nurses working in the emergency and intensive care unit from two public hospitals in Morocco. The study entailed semi-structured interviews transcribed verbatim until data saturation, guided by the grounded theory approach in order to explore the coaching requirements of emergency and intensive care nurses, and the measurement of the three dimensions of burnout with the Maslach Burnout Inventory (MBI). (3) Results: the results reveal three main conceptualizing explanatory categories of the nurses’ coaching requirements: Steps of a coaching action; topics for a coaching action related to occupational health issues such as stress and burnout (it is shown that the prevalence of burnout in our sample is 66.7%); barriers to a coaching action. (4) Conclusions: by investigating the coaching requirements of the nursing staff, a transtheoretical coaching model with a theoretical and ethical basis was suggested in this regard for their occupational health issues management.
Mechanisms of Infection in Zika Virus
Authors: Blázquez Ana Belén
Published: August 2023

Zika virus (ZIKV) is a mosquito-borne flavivirus that was first identified in Uganda in 1947, then was essentially neglected for six decades [...]
Prevalence of Infectious Hypodermal and Hematopoietic Necrosis Virus (IHHNV) in Farmed Procambarus clarkii of the Middle and Lower Reaches of the Yangtze River in China
Authors: Xu Feng , Wei Yongwei , Lu Jianfei , Chen Jiong
Published: August 2023

Procambarus clarkii is an important economic aquaculture species worldwide. Infectious hypodermal and hematopoietic necrosis virus (IHHNV) infects numerous crustacean hosts, including P. clarkii. However, there have been few reports on the prevalence of IHHNV in P. clarkii. In this study, 200 farmed P. clarkii were collected from Anhui, Jiangsu, Zhejiang, Hunan, Hubei, and Sichuan provinces in China. PCR detection was employed per the protocol by the World Organization for Animal Health (WOAH) to identify and detect the presence of IHHNV. The positive rate of IHHNV in different provinces ranged from 16.7 to 56.7%, and the overall IHHNV-positive rate was 38.5%. IHHNV strains isolated in this study related closely to infectious IHHNV and split into two major distinct branches. Besides, the IHHNV strains shared a high homology (93.4–99.4%). These findings suggest that a high prevalence of IHHNV was established in farmed P. clarkii in the middle and lower reaches of the Yangtze River.
Combined Bipolar Radiofrequency and Non-Crosslinked Hyaluronic Acid Mesotherapy Protocol to Improve Skin Appearance and Epidermal Barrier Function: A Pilot Study
Authors: Płatkowska Anna , Korzekwa Szymon , Łukasik Bartłomiej , Zerbinati Nicola
Published: August 2023

Background: Age-associated changes in epidermal hydration, pigmentation, thickness and cell renewal influence skin appearance and can lead to laxity, dryness and poor skin tone. The aim of this pilot study was to assess the synergistic effects of a new bipolar radiofrequency plus non-crosslinked hyaluronic acid (HA) mesotherapy protocol compared with radiofrequency alone on skin appearance and markers of epidermal function. Methods: This prospective, single-center, split-face pilot study recruited women aged 25–65 years with dryness and laxity of the facial skin defined by a trans-epidermal water loss (TEWL) value of ≥26 g/m2/h. Subjects were treated with a bipolar radiofrequency device on both sides of the face. This was immediately followed by needle hyaluronic acid (HA) treatment on one side of the face with 2.5 mL of a non-crosslinked HA. Photographic documentation, analysis of epidermal barrier function parameters, and high frequency (HF) ultrasound analysis were performed prior to treatment and at 28 days. Results: Twenty female subjects with a mean age of 46 (range 29 to 54) years and dry and lax facial skin were included. TEWL was reduced and skin hydration improved to a greater extent with the combined radiofrequency plus mesotherapy protocol compared with radiofrequency alone (−5.8% vs. +3.9% and +23.1% vs. +1.0%, respectively). The combined protocol was also associated with greater improvements in melanin (−7.5% vs. −1.5%) and erythema values (−7.2% vs. +3.0%), respectively. Ultrasound measures of epidermal thickness and epidermal density were greater after the combined protocol compared with radiofrequency alone (12.0% vs. 5.6% and 57.7% vs. 7.1%, respectively). Both treatments were well-tolerated. Conclusions: The combined bipolar radiofrequency and HA mesotherapy protocol provided greater improvements in skin hydration, firmness and tone compared with radiofrequency alone. The combination treatment was also associated with greater epidermal thickness and density and increased keratinocyte differentiation suggesting a synergistic effect of both treatments on epidermal homeostasis and barrier function. Both treatments were well-tolerated and led to improvements in facial appearance.