bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of Kaolin in the Pharmaceutical and Cosmetic Industries
Authors: Nurul Fadhilah
Published: May 2024

Kaolin, a white clay mineral composed mainly of kaolinite with the chemical formula Al2O3.2SiO2.2H2O, has been a subject of interest since the days of medieval western literature. This interest increased especially after the advent of a more empirical approach to pharmacology, the establishment of pharmacopoeias, and developments in mineralogy, chemistry, as well as pharmaceutical technology. The use of kaolin in pharmaceutical (both topical and oral) and cosmetic applications has become important. Although it has long been recognized as a remedy in traditional medicine, the use of kaolin as an active ingredient for various diseases continues to be researched. Unfortunately, research focused on the use of kaolin in pharmaceuticals and cosmetics is still fairly limited. Therefore, this article aims to highlight the role and benefits of kaolin in both fields. Kaolin has been shown to have antibacterial, antiviral, and antidiarrheal properties when administered orally, as well as serve as a skin-protective agent when used topically. Aside from being an active ingredient, kaolin is also often used as an excipient in pharmaceutical formulations, acting as a filler, emulsifier, suspending agent, and crusher. In the cosmetic world, kaolin is often used as a sunscreen and to treat the skin. This article is organized based on a literature review of various articles and journals relevant to the topic discussed.
Biofarmasetics and Pharmacokinetics Study Analysis of Paracetamol Excretion Through Urine and Saliva
Authors: Fikria Nahla Akila
Published: May 2024

The purpose of this study was to determine that Paracetamol, also known as acetaminophen, is a commonly used analgesic and antipyretic drug to relieve pain and reduce fever. The process of metabolism and elimination of paracetamol from the body is important to understand, especially in the context of the safe use of this drug. This study aims to analyze the biopharmaceutics and pharmacokinetics studies of paracetamol excretion through urine and saliva as important indicators in understanding the metabolic and elimination processes of this drug. Paracetamol is rapidly and efficiently absorbed through the gastrointestinal tract, reaches the highest concentration in plasma in a short time, and is dispersed throughout the body fluids. The metabolic process of paracetamol mainly occurs in the liver, through two main phases: oxidation and conjugation with glucuronic and sulfuric acids.  Excretion of drugs and their metabolites can occur through urine and saliva, with the kidney as the main organ in the excretion process. Qualitative analytical methods were used in this study to identify paracetamol metabolite compounds in urine and saliva samples and to evaluate the metabolic pathways involved. Glucoronide, sulfate, and phenol conjugate assays were used to detect the presence of paracetamol metabolites in the samples. The assay results showed that urine was more effective in excreting paracetamol compared to saliva. In conclusion, this study provides a better understanding of the metabolic process and elimination of paracetamol from the human body through the analysis of biopharmaceutics and pharmacokinetics studies. These results are important for understanding the therapeutic effects and toxicity of paracetamol as well as for developing more effective and safe drug use management strategies.
Nanoteknologi Farmasi Ziprasidone Nanocrystals By Wet Media Milling Followed By Spray Drying AndLyophilization: Formulation And Process Parameter Optimization
Authors: Mutiara Deas Tantia  , Nahla Akila Fikria  , Vio Agister Risanl
Published: May 2024

lyophilisation. The research methods used include the preparation of Ziprasidone nanosuspension using size reduction technique, optimisation of process parameters, formulation of media milling technique, and evaluation of the physical stability of the optimised nanosuspension. The results of this study are expected to provide a better understanding of the use of nanocrystals in improving the solubility and bioavailability of drugs with poor solubility such as Ziprasidone. In addition, this study is also expected to provide new insights into the use of spray drying and lyophilisation technologies to improve the physical stability of drug nanosuspensions. In conclusion, this study highlights the importance of using nanocrystals in improving the solubility and bioavailability of drugs with poor solubility such as Ziprasidone. Spray drying and lyophilisation methods have been shown to be effective in improving the physical stability of drug nanosuspensions. This research can serve as a foundation for the development of more effective drug formulations that can be used in wider clinical applications.
Algunas reflexiones sobre la dimensión narrativa en Alasdair Macintyre. Una propuesta ética, desde la lógica narrativa, para la rehumanización de Venezuela
Authors: Urbina Mendoza Emilio J.
Published: May 2024

Una de las manifestaciones de la crisis de la sociedad contemporánea, centra su atención en el agotamiento de un modelo lógico referencial. Las lógicas que fueron consecuencias de la primera modernidad poco a poco encontraron dificultades para responder a los grandes cuestionamientos del mundo actual, donde, la cultura del relativismo muestra su mayor fortaleza en la concreción de no lugares y del vaciamiento ético colectivo. Los modelos analítico y dialéctico, ambos con altísima proyección durante el siglo XX, lucen hoy agotados como referentes con las respuestas a las interrogantes éticas actuales. Para ello, estudiaremos en este trabajo la propuesta neo-tomista de Alasdair Macintyre, expresada en la denominada “lógica narrativa”. Con ello, proponemos un referente no sólo lingüístico, sino ético, para facilitar respuestas de rehumanización frente a la crisis terminal venezolana.
STANDARDIZATION OF GRAFTING HEIGHT FOR GROWTH AND DEVELOPMENT OF MANGO (Mangifera indica L.) NURSERY PLANTS
Authors: Hamza Ameer , Razzaq Kashif , Umair Muhammad , Hussain Abid , Zafar Muhammad S. , Rehman Asif Ur
Published: May 2024

Grafting height has a significant impact on plant growth and the development of many fruits including mango. The present study was planned to optimize the height of mango rootstock for grafting at the nursery level. Three different varieties of scion (Sindhri, Sufaid Chaunsa, Chenab Gold) were grafted at three different heights (8inch, 12inch and 16inch) using wedge/cleft grafting technique on desi mango nursery seedlings. Results showed that grafting height and scion variety have a significant impact on the growth and development of mango nursery plants. Different parameters were examined and results showed that Sindhri scion grafted at 16 inches’ height significantly improved, number of flushes (2.62), number of leaves (14.55), stem girth (14.25mm), plant height (56.16cm), scion length (18.62cm), superoxide dismutase (3.70 U mg-1 protein), peroxidase (0.96 U mg-1 protein), chlorophyll b contents (6.6 g/kg).  However, the scion of Chenab Gold grafted at 12 inches, performed best for grafting survival percentage (97.5 %). So it was concluded that Chenab Gold Scion performed best at 16 inches grafting height for plant growth in all aspects as compared to other scion varieties and grafting height.
Embolization of Arteriocavernous Fistula in Arterial Priapism: A Clinical Case
Authors: Gamidov S. I. , Akinfiev D. M. , Shatylko T. V. , Mammaev R. U. , Rodin I. M.
Published: May 2024

Arterial priapism occurs much less frequently than venous (non-ischemic, low-flow) priapism. Considering the absence of ischemia of the cavernous bodies in arterial priapism, emergency surgical intervention is usually not indicated, and a wait-and-see approach is acceptable. In the absence of spontaneous resolution of arterial priapism, invasive treatment may be performed upon the patient’s desire. Currently, the method of choice is super-selective embolization of branches of the internal pudendal, cavernous, or helical artery. This article presents a clinical case of arterial priapism, in which super-selective embolization of the cavernous artery with PVA (polyvinyl alcohol) embolization agent was performed, resulting in complete resolution of priapism after the operation.
The role of zinc in a healthy prostate gland and in chronic prostatitis
Authors: Bratchikov O. I. , Tyuzikov I. A. , Grekov E. A. , Novikov A. V.
Published: May 2024

The review article discusses modern aspects of the physiological role of zinc in the prostate gland, as well as the consequences for the prostate gland of deficiency of this one of the most important vital trace elements. The mechanisms of intracellular zinc transport, as well as various physiological processes in prostate tissue requiring the mandatory presence of zinc, are covered in more detail. In a separate section of the literature review, the modern evidence base of the relationship of zinc deficiency in the prostate gland with chronic prostatitis is presented and the results of modern studies showing the need for zinc replacement therapy in the framework of complex pharmacotherapy of chronic prostatitis occurring against the background of zinc deficiency are summarized.
Sex Steroids Binding Globulin: the evolution of views about biological functions and diagnostic significance in normal and pathological conditions
Authors: Grekov E. A. , Dzidzaria A. G. , Tyuzikov I. A.
Published: May 2024

Sex steroid hormones (androgens, estrogens) play a critical role in the endocrine regulation of human body functions in normal and in various pathologies. Numerous complex mechanisms of their transportation from the site of synthesis to target cells are involved in the process of realization of their functions by sex steroid hormones, among which the most important role is played by sex steroids binding globulin (SSBG), synthesized in the liver and entering the systemic circulation. Until recently, SSBG was considered practically only as a specific transport system of sex steroids (androgens, estrogens) to target cells. Early studies have demonstrated an increase in the SSBG level in the blood as a person’s age increases, however, only relatively recently a polymorphism of the SSBG gene was established, which determines the genetically determined different degree of affinity of this transport protein to sex steroid hormones (androgens, estrogens) in different people, which allows us to consider SSBG not only as a unique individual transport protein of blood, but also as a unique serum regulator of the activity and tissue bioavailability of sex steroids. Modern studies have also shown close interrelations of the serum level of GSPS with some human diseases, which allows us to consider this transport protein not only as their potential serological marker, but as a direct independent mechanism of their pathogenesis.
Scientific and technical research in the field of transport, Volume 2
Authors:   Non-Government Organization ", Klymenko Viktoriia ,   Academy of Technical Sciences of Ukraine", Pron Svitlana ,   Non-Government Organization "Academy of Technical Sciences of Ukraine", Prymachenko Hanna ,   Non-Government Organization "Academy of Technical Sciences of Ukraine", Protsyk Oleksandr ,   Non-Government Organization "Academy of Technical Sciences of Ukraine", Silantieva Iuliia ,   Non-Government Organization "Academy of Technical Sciences of Ukraine", Bahrii Mariia ,   Non-Government Organization "Academy of Technical Sciences of Ukraine"
Published: May 2024

У монографії наведені основи організації логістики у мультимодальних транспортних системах за участю залізничного транспорту, запропоновані шляхи розвитку спеціалізованих і нетрадиційних видів транспорту в Україні, наведені результати проектування транспортно-термінальних систем доставки вантажів при управлінні ланцюгами постачань, здійснено моделювання процесу доставки вантажів у змішаному сполученні, розглянуто питання інтеграції транспорту в мультимодальних системах, а також питання безпеки польотів повітряних суден цивільної авіації в контексті сервісної діяльності авіаційних підприємств.
Basics of organizing logistics in multimodal transport systems with the participation of railway transport
Authors:   Non-Government Organization ", Prymachenko Hanna ,   Academy of Technical Sciences of Ukraine"
Published: May 2024

Розглянуто проблематику організації інформаційних потоків у мультимодальних транспортних системах на основі віртуальних кластерів мультимодальних перевезень. Доведено необхідність управління інформацією у віртуальному кластері мультимодальних перевезень з метою розвитку транспортних систем при взаємодії залізничного та морського транспорту.
Design of transport and terminal systems for the delivery of goods in the management of supply chains
Authors:   Non-Government Organization ", Protsyk Oleksandr ,   Academy of Technical Sciences of Ukraine"
Published: May 2024

Зазначено актуальність питання визначення основних параметрів транспортно-термінальних систем доставки вантажів при управлінні ланцюгами постачань. Логістичний підхід до організації діяльності транспорту вказує на необхідність розгляду даного питання. Наведено приклад розробки транспортно-термінальних систем при доставці вантажів з Європи в Азію.
Modeling the process of cargo delivery in a mixed connection
Authors:   Non-Government Organization ", Silantieva Iuliia ,   Academy of Technical Sciences of Ukraine"
Published: May 2024

З огляду на появу проривних транспортних технологій проектування, розробка та розгортання цифрових платформ для прийняття оперативних рішень щодо організації доставки вантажів у змішаному сполученні є актуальною задачею. На сьогодні її можна вирішити за допомогою новітніх технологій обробки великих обсягів даних, процесної аналітики і блокчейну. Розвинені країни світу продемонстрували переваги реалізації цих технологій на прикладі систем єдиного вікна, імплементованих для здійснення ефективного державного контролю митними службами, а також для зручності транспортних компаній, мультимодальних операторів, експортерів, імпортерів тощо. Розглянуто декілька питань, рішення яких доцільно автоматизувати при моделюванні синхромодальних перевезень в рамках таких цифрових платформ.
Wood-cutting circular saws with a combined toothed crown
Authors:   Non-Government Organization ", Taras Vasyl ,   Academy of Technical Sciences of Ukraine", Pylypchuk Maria ,   Non-Government Organization "Academy of Technical Sciences of Ukraine", Lazarchuk Kateryna ,   Non-Government Organization "Academy of Technical Sciences of Ukraine", Salovskyi Stepan ,   Non-Government Organization "Academy of Technical Sciences of Ukraine"
Published: May 2024

Висвітлено результати теоретичних та експериментальних досліджень процесу поздовжнього розпилювання деревини круглими пилками із комбінованим зубчастим вінцем. Встановлено закономірності впливу конструкційних параметрів зубців пилки на точність та енергоємність процесу пиляння. Розроблено нову конструкцію пилки із комбінованим зубчастим вінцем, що забезпечує підвищення робочої жорсткості пилки та дає змогу розпилювати деревину з точністю ±0,5 мм, а також знизити енергоємність процесу пиляння на 30%. Отримано рівняння регресії для визначання поля розсіювання розмірів деталей та потужності різання під час розпилювання деревини пилкою з комбінованим зубчастим вінцем залежно від швидкості подавання, висоти пропилу та породи деревини, які дають змогу прогнозувати точність обробляння та встановлювати раціональні режими пиляння.
A research study of people with disabilities development in Brunei Towards the development of human capital : a case of disabilities
Authors: Izzaty Dyg Nurulsyazwany , M.Shaikh Dr.Junaid , Talha Dr. Mohammad
Published: May 2024

This research paper is the analyze and study development of People with Disability (PWD) in Brunei Darussalam and to understand government role in helping  People with Disabilities (PWD) between Brunei, Malaysia and Singapore in terms of employment. The research begins with analyzing the objectives and the needs of this research to conduct. The methodology conducted using primary data and secondary data in order to get the source of data, such as conducting Interviews, distributing questionnaire survey, and through research papers, journals and articles. The questionnaire used was to get public perceptions of People with Disabilities (PWD) in Brunei. To a certain extent, the outcomes from the findings tells that not all public are aware of the government’s support for People with Disabilities (PWDs) in being employed. Overall, all the discussion shows that other countries has a better assistance towards the People with Disabilities (PWDs) compared to Brunei.
A Practical Analysis on the Integration of College Students’ Labour Education into Rural Revitalisation from the Perspective of “Hundred, Thousand, and Ten Thousand Project”
Authors: ZHANG Xuan , GENG Qi
Published: May 2024

The key to rural revitalisation lies in the revitalisation of talents, the core of which lies in the cultivation of high-quality talents who are united in knowledge and action. Colleges and universities, as the gathering place of high-quality talents, should give full play to their important role in cultivating talents through labour education. Labour education has the important value of improving college students' sense of social responsibility and self-worth, and promoting employment and entrepreneurship. In practice, it is necessary to raise the awareness of the importance of labour education for rural revitalization, establish a robust management mechanism for labour education and a sound safeguard mechanism for talents, organically integrate labour education with on- and off-campus social practice, build a diversified evaluation system with the sense of achievement of the students as the core, and build a system of labour education for colleges and universities at the conceptual, systemic, practical and evaluation levels, to explore a new path for labour education to integrate into rural revitalization, and to promote rural revitalization in a powerful and effective way.
The Potential Use of QR Codes in u-Learning Systems
Authors:   College of Computer Studies, University of Antique, Sibalom, Antique, Philippines, Mission Roger , Saylo Monalie ,   Laboratory Highschool – College of Teacher Education, University of Antique, Sibalom, Antique, Philippines
Published: May 2024

The proliferation and advancement of technologies have made learning become more interactive and innovative. Technology has become an essential component of today’s educational systems as most learners in this generation are attached to technology. Integrating technology in u-Learning systems may somehow help drive the attention of students toward learning. Teachers may have already used a number of information and communications technology (ICT) tools in education to improve their classroom instructions. This paper discusses the potential use of QR codes as an effective education technology tool in u-Learning systems. This study further discusses how QR codes can be used inside or outside the classroom. With the students’ own personal mobile devices and the teacher’s creative ideas, QR codes can be a tool for interactive and enjoyable learning.
Development of Online Counseling Appointment System for Guidance Office of the Office of Student Affairs and Services at Cavite State University-Main
Authors:   College of Engineering and Information Technology, Cavite State University – Main Campus, Philippines, Bondoc Mark Kenneth , Rabosa Lucky Angelo ,   College of Engineering and Information Technology, Cavite State University – Main Campus, Philippines, Peji Joy ,   College of Engineering and Information Technology, Cavite State University – Main Campus, Philippines
Published: May 2024

Every guidance counselor finds remote appointments an important tool for managing appointments since it allows them to establish a list of available time slots, see student information, and make appointments without ever leaving their office. This online counseling appointment application provides students with media-related mental health activities and stress-coping skills that are relevant to the university’s counseling services. Specifically, it has the following features: (a) provides information to the students related to some guidance on how to cope with stress; (b) generates reports to be used by a guidance counselor in providing insight they need to effectively counsel so many students; and (c) helps the guidance counselor extend their counseling service to the student. The descriptive research approach was used with JavaScript as the scripting programming language and MySQL as the database. The prototyping software approach was also used, allowing the researcher to come up with additional ideas rapidly, improve on them quickly, and show users the feature and overall design concept before implementation. The evaluation findings show that the system was "excellent" in both evaluations using modified ISO 9126 software product quality standards, showing that the developed application met all of the required requirements of the software quality test from respondents. The mean and standard deviation were used to tabulate, analyze, and statistically treat the results. Overall, the results and feedback indicate a good impact on the needs of guidance counselors.
A Malay Queen’s Siamese Silver Bowl at the V&A
Authors:   Asian Civilisations Museum & Peranakan Museum, Wang Naomi
Published: May 2024

This notice examines a nielloware silver bowl at the V&A Museum, originally from southern Thailand. Using Jawi inscriptions, the notice unravels the bowl’s significance as a royal Malay heirloom. The bowl’s intricate scenes depict Hindu–Buddhist mythical creatures and celestial beings. The royal seal found on the base is attributed to Queen Tengku Ambung Fatimah (r. 1883‒?). Another Jawi inscription traces a lineage, identifying two other royal women, Engku Besar and Engku Lebar as previous owners. The bowl was eventually dispersed from the Riau–Lingga court, likely after the sultanate was dissolved in 1911, before reaching Singapore and London. This artifact serves as a symbol of lineage, power, and transnational movement in a 19th-century maritime court.
Book Reviews
Authors: Hendrickson Mitch , Sather Clifford , Forest Alain , Bautze Joachim K. , Tej Bunnag Tej , Cohen Paul T. , Baffie Jean , Boonwanno Thanida , Clark John , Purichanont Vipash
Published: May 2024

Book Reviews
Oskar Frankfurter: A Biographical Reconstruction
Authors:   Universität Hamburg, Grabowsky Volker
Published: May 2024

This article reexamines the life of Dr Oskar Frankfurter (1852–1922), co-founder and president of the Siam Society from 1906 to 1917. Despite his impactful contributions to Thai studies and culture during his tenure as chief librarian of the Vajirañāṇa National Library, his life remains shrouded in obscurity. Drawing from recently discovered archival sources in Thailand, Germany, and the UK, the article explores Frankfurter’s early years in Hamburg, his influential career in Siam from 1884 to 1918, and his role in establishing Thai Studies in Germany. The narrative is structured to cover key life phases, offering a glimpse into the fascinating legacy of this forgotten luminary.
The Great Disciple Mahākassapa and his Parinibbāna
Authors:   École Pratiques des Hautes Études, Schnake Javier
Published: May 2024

Online Appendices
Teaching Introductory Microeconomics— The Full Treatment
Authors: Penn William M.
Published: May 2024

Choices and decisions in business and in economics as well as in life are not made in an ethical vacuum. There are few economic choices that are ethically neutral. By their very nature, choices/decisions involve the worldview of the chooser/decision-maker, and this can cause two individuals possessing an equal knowledge of the same educational tools to make widely different choices when faced with the same alternatives. Consequently, the teaching of microeconomics principles will always be lacking without the infusion of an ethical/philosophical system which gets at how to properly use these principles and tools. This paper will propose that microeconomic principles and tools are best applied using a biblical model and that decision-makers with non-Christian worldviews often make choices based on biblical principles because the latter work best even in a fallen world (II Timothy 3:16). The difference here is in motivation; the Christian’s motivation is to serve Jesus Christ. On the other hand, Christians do not always follow biblical principles because ideal behavior is sometimes compromised due to expediency, greed, or other wrong motives.
Considering the Data Analytics Revolution and Lessons for Christian Business Faculty
Authors: Manlapig Enrico , Ko Elayne
Published: May 2024

Data is playing an increasingly important role in business. The demand for skilled data analysts and data scientists is growing rapidly. In response, universities and colleges are creating new programs to meet the swelling demand and distinctively Christian universities and colleges, too, are adding programs in data analytics. This paper comments on the trend toward data-driven decision making and offers both exhortation and caution to Christian educators and practitioners moving in this direction.
The Tyranny of Metrics: An Overview
Authors: Dulaney Emmett
Published: May 2024

Muller, J. (2018). The tyranny of metrics. Princeton: Princeton University Press. 978-0-691-174952, 240 pp, https://press.princeton.edu/titles/11218.html
Letter from the Editor
Authors: Dulaney Emmett
Published: May 2024

It is often said that a picture is worth 1,000 words.
Endings
Authors: Dulaney Emmett
Published: May 2024

Endings
A Holistic Model for Faith Integration: Transformational Learning Theory as a Vehicle for Shaping a Christian Identity
Authors: Wallace J. Randall
Published: May 2024

Using transformational learning theory as an andragogical approach, this paper explores a holistic faith integration model that emphasizes a student’s identity in Christ as a key area of focus. The paper seeks to define the end product. What does a student look like after going through years of faith integration at the institution? Issues of identity are explored that include internalizing the being habits of a disciple, developing a biblical worldview, developing self-motivated autonomous learners, and instilling an approach to life that is transformative. How transformational learning theory impacts instructor behavior and methods used is briefly discussed.
Four Models for Conducting the Introductory Business Course
Authors: Gerdes Darin , Fuss Matthew , O'Brien Ross , Rollins Maxwell , Rudebock Rich
Published: May 2024

The introduction to business course provides a critical opportunity to mold students’ perceptions about business. In this paper, the authors discuss four different approaches to conducting introductory business courses. These include a survey of the discipline, a philosophical approach, a discipline-specific approach, and an entrepreneurial venture approach. Regardless of format, these approaches focus on the integration of theological constructs and recognize the value of molding students from the start of their academic journey.
Endings
Authors: Dulaney Emmett
Published: May 2024

Endings including manuscript guidelines
Christian Identity, Counteractive Control, and Business Ethics
Authors: Gratton Paul , Dukas Stephen
Published: May 2024

This paper reviews the literature on counteractive control and moral identity formation and explores how these theories apply to teaching business ethics in Christian higher education. We propose that institutions of Christian higher education have an opportunity to promote students’ ethical resolve based on their ethical identity formation based on the person of Jesus Christ. This paper provides practical implications of these theories on pedagogy within higher education and suggests potential directions for future research.
The New Testament Church as an Exemplar Organizational Culture
Authors: Jones Benton
Published: May 2024

This article builds on management education’s emphasis on organizational culture by offering the New Testament church as an exemplar culture. The culture of the New Testament church is exposited from a study of New Testament prescriptions for the behavior of followers of Christ. Instructions and instructor resources for a classroom exercise are included in which students interact with these passages, form their own summary of New Testament culture, and make application to the workplace.
Applying the Imago Dei Using Agency Theory: An Intuitive Active Learning Exercise for the Management Classroom
Authors: Jones Benton , Musick Rob
Published: May 2024

A management instructor and a religion instructor collaborated to create an instructional exercise for the application of agency theory using the theological concept of the Imago Dei. The result is a simple method for management instructors to help business students understand the roles of a manager from a biblical worldview. The attributes of God and the imago Dei are common elements of most Christian traditions but are often difficult concepts to introduce to undergraduate students as they apply to management theory. This exercise offers an intuitive approach for management instructors using agency theory.
At Work on Purpose
Authors: Smith Daryl
Published: May 2024

Many Christians struggle with how to live out their Christian faith at work. This manuscript presents an organization, At Work on Purpose (AWOP), that has successfully helped Christians do just that. The story explores the history and inner workings of AWOP, allowing the reader to understand how the organization functions to help Christian millennials and Generation Z enter and get established in the workforce. The unfolding story reveals challenges the organization faces related to leadership succession and can be used by management professors to stimulate classroom discussion on this topic.
The discursive formation of British national identity: the lexical aspect
Authors: Vlasova Vlada Vladimirovna
Published: May 2024

British national identity has been in the zone of constant study by scientists for a long period of time, but after Brexit, interest in this topic has increased significantly. The British nation, especially the part of it that was on the side of the Eurosceptics, after Brexit was aimed at strengthening the British identity and completely destroying any influence of globalization on the British nation. But despite the expectations of the British, many scientists agree that the national British identity is still in crisis. Thus, the object of this research is the culture-bound lexical elements of the English-language political discourse of online mass media, and the purpose is to identify the current state of British national identity through the analysis of the words-realities of the British political discourse. Current works (not older than five years) by Russian and foreign scientists in the fields of political discourse and national British identity form the methodological basis of the research. The analysis of the culture-bound lexical elements of English-language political discourse is carried out on the basis of online media texts for the period January–April 2024, which makes the study innovative and reflects the trends of modern linguistic science. As a result of the study, it was revealed that the national British identity is in a state of crisis. Brexit and subsequent events gave the British nation hope for the ascent of national identity and the return of its former imperial greatness, but analyzing the current articles of British online publications on political topics, it becomes evident that international processes still prevail over the British identity. The further perspective of the research lies in the field of studying the discursive formation of British identity from the point of view of syntactic, grammatical, and social aspects.
Caffeoylquinic acid profiling: comparative analysis in yerba mate, Indian camphorweed, and stevia extracts with emphasis on the influence of brewing conditions and cold storage in yerba mate infusion
Authors: Khaksar Gholamreza , Chaichana Nantachaporn , Assatarakul Kitipong , Sirikantaramas Supaart
Published: May 2024

Herbal infusions exhibit diverse pharmacological effects, such as antioxidant, anti-inflammatory, anticancer, antihypertensive, and antineurodegenerative activities, which can be attributed to the high content of phenolic compounds (e.g., caffeoylquinic acids (CQAs)). In this study, we used ultraperformance liquid chromatography to determine the content of CQAs in the methanolic extracts of model herbs, namely, yerba mate (Ilex paraguariensis), stevia (Stevia rebaudiana), and Indian camphorweed (Pluchea indica (L.) Less.). The results revealed that yerba mate had the highest total CQA content (108.05 ± 1.12 mg/g of dry weight). Furthermore, we evaluated the effect of brewing conditions and storage at 4 °C under dark and light conditions on the antioxidant property and total phenolic and CQA contents of a yerba mate infusion. The analysis of the yerba mate infusions prepared with different steeping times, dried leaf weights, and water temperatures revealed that the amount of extracted CQAs was maximized (∼175 mg/150 mL) when 6 g of dried leaves were steeped in hot water for 10 min. A total of 10-day refrigerated storage resulted in no significant changes in the antioxidant activity and total phenolic and CQA contents of an infusion kept in a brown container (dark). However, the antioxidant properties and total phenolic and CQA contents were negatively affected when kept in a clear container, suggesting the detrimental effect of light exposure. Our study provides practical recommendations for improving the preparation and storage of herbal infusions, thus catering to the needs of consumers, food scientists, and commercial producers. Moreover, it is the first study of the influence of light exposure on the content of crucial quality attributes within plant-based beverages.
Astronomy school education in Chile: perspectives and connections from the National Curriculum, teachers’ content knowledge, and professional development programs
Authors:   , Rodrigues de Andrade Lara
Published: May 2024

La astronomía tiene gran potencial para atraer a los niños hacia las ciencias y mejorar su alfabetización científica. Sin embargo, en Chile, sede de los telescopios más grandes del mundo, la educación astronómica aun se está desarrollando y tiene poca investigación. Esta tesis tiene como objetivo caracterizar la educación astronómica escolar en Chile considerando perspectivas y conexiones desde el currículo, el conocimiento disciplinar docente y los programas de desarrollo profesional (DP). Primero, se caracterizaron las oportunidades de aprendizaje de astronomía en el currículo de ciencias de 1º Básico a 4º Medio, y se encontró que contiene un pequeño porcentaje de contenidos astronómicos, pero hay oportunidades de abarcar más tópicos a través de trabajo interdisciplinar. Segundo, se mapeó el conocimiento astronómico de 171 docentes de educación básica y media, mostrando un bajo nivel de conocimiento de astronomía en la muestra, especialmente en tópicos del día-a-día, los cuales son obligatorios en el currículo. Tercero, se caracterizaron 16 programas DP de astronomía para profesores según criterios de efectividad, encontrándose que la mayoría logra alinearse con el currículo y ofrecer actividades prácticas, pero pocos han evaluado conocimiento y efectividad, o han hecho seguimiento a los profesores. Estos resultados pueden contribuir a este campo de investigación emergente con una vista sistémica de la educación astronómica escolar y ayudar a instituciones de astronomía en Chile a ofrecer programas educativos con más efectividad e impacto.
Retención de estudiantes en la educación pública en su transición a la enseñanza media: desafío de elevar la matrícula para el SLEP Gabriela Mistral
Authors:   , Ramírez Bahamondes Miriam Jacqueline
Published: May 2024

La actual reforma del Sistema de Educación Pública en Chile ha enfrentado una diversidad de desafíos a través de la implementación de los Servicios Locales de Educaciones Pública (SLEP). Uno de estos desafíos es el aumento de la matrícula de estudiantes y la importancia que cobran quienes lideran este nuevo sistema educacional. Utilizando una adaptación de la metodología del Design Thinking, el siguiente trabajo propone – a partir de una investigación profesional que considera el análisis de datos cuantitativos y cualitativos - diseñar estrategias a nivel del SLEP Gabriela Mistral que favorezcan la permanencia de los/as estudiantes en su transición a la enseñanza media, y por medio de ello contribuir a fortalecer su liderazgo educativo en su territorio.
La producción social de la dis/capacidad en una universidad chilena de elite y excelencia
Authors:   , Masihy Vega Tiare
Published: May 2024

En este trabajo mapeo la producción de la dis/capacidad mediante un programa de inclusión para estudiantes con discapacidad en una universidad chilena de elite, excelencia, y con altos estándares de inclusión. Aunque diversos aspectos producen mejores experiencias educativas, el programa analizado parece priorizar elementos académicos sin tener políticas claras de orden social, afectivo, entre otros. Esto es problematizable porque las dificultades de estudiantes con discapacidad para enfrentar las exigencias académicas de la universidad, son una barrera para su permanencia en este espacio. Además, la ausencia del capacitismo como categoría analítica en diagnósticos institucionales, ha sido una constante en investigación sobre discapacidad y educación superior. Considerando todo esto, planteo la pregunta: ¿cuál es la lógica de funcionamiento del ensamblaje que está produciendo la discapacidad mediante el programa? Para responderla, analizo políticas de inclusión y discapacidad en educación superior, y realizo entrevistas a funcionarias del programa. Luego, configuro un policyscape, y mapeo el devenir del programa y la producción de la discapacidad utilizando teoría de ensamblaje. Los resultados indican que la lógica del ensamblaje puede caracterizarse como capacitista y productivista, lo que es coherente con la educación superior, y de excelencia, lo que es intensificado por la institución. Además, el programa parece tener un rol clave en la producción de la discapacidad en la universidad. Por último, sugiero mejoras para el programa y las políticas analizadas, abordo proyecciones y limitaciones de esta investigación, y reflexiono sobre mi proceso de posicionamiento profesional.
“El poema Escotida o vida del Doctor Sutil Escoto” (1744), de fray Gregorio Farías, un antecedente americano del dogma de la Inmaculada Concepción
Authors: Álvarez-Gutiérrez Rodrigo
Published: May 2024

Durante la época colonial, en algunos países de Iberoamérica, se desarrolló un movimiento teológico que tuvo como centro el pensamiento escotista. Si bien la complejidad de las ideas de este franciscano abarcó muchos aspectos de las verdades de fe, su impronta se manifestó claramente en un poema escrito por un religioso chileno: Gregorio Farías. Este, siguiendo los parámetros de la épica heroica de corte sacro, dio a luz una obra conocida como la “Scotida”. Allí puso en valor el tema de la Inmaculada Concepción antes de su promulgación dogmática, abordando los ejes que justifica su inclusión en el depósito de la fe. Este estudio analiza los aspectos mariológicos más relevantes de esta obra, anterior a la bula Innefabilis Deus.Durante la época colonial, en algunos países de Iberoamérica, se desarrolló un movimiento teológico que tuvo como centro el pensamiento escotista. Si bien la complejidad de las ideas de este franciscano abarcó muchos aspectos de las verdades de fe, su impronta se manifestó claramente en un poema escrito por un religioso chileno: Gregorio Farías. Este, siguiendo los parámetros de la épica heroica de corte sacro, dio a luz una obra conocida como la “Scotida”. Allí puso en valor el tema de la Inmaculada Concepción antes de su promulgación dogmática, abordando los ejes que justifica su inclusión en el depósito de la fe. Este estudio analiza los aspectos mariológicos más relevantes de esta obra, anterior a la bula Innefabilis Deus.
Activity-Based Concept Towards Office Building in Jakarta
Authors: Melyna Melyna , Priyomarsono Naniek Widayati , Lianto Fermanto
Published: May 2024

Post-COVID-19 pandemic work activities faced a readjustment, but work activities are now more flexible regarding place and time. Therefore, it is necessary to reconsider current work activities, which are now based on the workers’ activities. Office buildings are a main physical factor in comfort and worker productivity. With an activity-based concept based on the worker’s activities, office building configuration is based on the needs of each worker at a time and consists of several types of workspaces. The research uses the multiple case study method to reassess the role of office buildings in current work activities. The design method used is Bernard Tschumi’s programming theory. The activity-based concept is structured based on elements of the physical work environment implemented in several types of work areas according to needs, with the most significant space configuration being the facility area.
Linear stability analysis of two‐layer rectilinear flow in slot coating
Authors: Nam Jaewook , Carvalho Marcio S.
Published: January 2010

Two‐layer coating occurs in many products. Ideally, the liquids are deposited onto the substrate simultaneously. In the case of two‐layer slot coating, the interlayer between the coating liquids is subjected to enormous shearing. This may lead to flow instabilities that ruin the product. It is important to map the regions of the parameter space at which the flow is unstable. Most of the stability analyses of two‐layer rectilinear flow consider the position of the interlayer as an independent parameter. Classical results cannot be applied directly in coating flows. We present a linear stability analysis of two‐layer rectilinear flow considering the flow rates as an independent parameter. The predicted neutral‐stability curves define the region of stable flow as a function of the operating parameters. The range of coating operating conditions is restricted further, when the condition for the desirable interlayer separation point location are considered together with the stability condition. © 2010 American Institute of Chemical Engineers AIChE J, 2010
A descriptive force‐balance model for droplet formation at microfluidic Y‐junctions
Authors: Steegmans Maartje L. J. , De Ruiter Jolet , Schroën Karin G. P. H. , Boom Remko M.
Published: January 2010

In a previous article, we studied the basics of emulsification in microfluidic Y‐junctions, however, without considering the effect of viscosity of the disperse phase. As it is known from investigations on many different microstructures that viscosity and viscosity ratio are governing parameters for droplet size, we here investigate whether this is also the case for microfluidic Y‐junctions and do so for a wide range of process conditions. The investigated Y‐junctions have a width of 19.9 or 12.8 μm and a depth of 5.0 μm, and the formed monodisperse droplets (CV < 1%) are between 3 and 20 μm. We varied the disperse‐phase viscosity using different oils (1–105 mPa s), and continuous‐phase viscosity using glycerol–water and ethanol–water mixtures (1.0–6.2 mPa s), which corresponds to disperse‐to‐continuous‐phase viscosity ratios from 0.4 to 105.0. Through the variation of the liquids, also a range in interfacial tensions (12–55 mN m−1) is assessed. The disperse‐phase flow rate is varied from 0.039 to 18.0 μL h−1, the continuous‐phase flow rate from 1.39 μL h−1 to 0.41 mL h−1, and this corresponds to flow rate ratios from 1.1 × 10−3 to 0.14, which is once again based on wide range of conditions. For all these conditions, in which droplets are formed in the dripping and jetting regime, the droplet size could be described with a model based on the existing force‐balance model, but now extended to incorporate the cross‐sectional area of the droplet and the resistance with the wall. Surprisingly enough, it was found that the droplet size is not influenced by the disperse‐phase viscosity, or the viscosity ratio, but it is dominated by the resistance with the wall and the continuous‐phase properties. Because of this, emulsification with Y‐junctions is intrinsically simpler than any other shear‐based method as droplet size is only determined by the continuous phase. © 2010 American Institute of Chemical Engineers AIChE J, 2010
An investigation into the dynamics of chalcopyrite bioleaching
Authors: Kotsiopoulos Athanasios , Hansford Geoffrey S. , Rawatlal Randhir
Published: January 2010

A study was undertaken to investigate the dynamics of chalcopyrite bioleaching. The analysis revealed significant dynamics features because the chemical leaching rate of chalcopyrite does not vary monotonically with solution redox potential but undergoes a maximum followed by a minimum as potential increases. The analysis does account for reaction passivation, an effect that has consistently been reported in the literature. The existence and stability of steady states were determined as functions of the solution redox potential, reactor temperature, and biomass concentration. It was found that the rate of bioleaching increased with temperature at lower overall solution potentials with competitive rates observed at high ferric/ferrous ion ratios. Both high and low overall bioleaching rates were observed with increasing biomass concentration, indicating an upper concentration limit before passivation. These results indicate that the frequently observed inhibiting rates may simply be artifacts of the system dynamics rather than due to physical phenomena. © 2010 American Institute of Chemical Engineers AIChE J, 2010
Dose‐intensified treatment of Burkitt lymphoma and B‐cell lymphoma unclassifiable, (with features intermediate between diffuse large B‐cell lymphoma and Burkitt lymphoma) in young adults (<50 years): A comparison of two adapted BFM protocols
Authors: Tauro Sudhir , Cochrane Lynda , Lauritzsen Grete Fossum , Baker Lee , Delabie Jan , Roberts Claudia , Mahendra Premini , Holte Harald
Published: January 2010

The chemotherapy dose‐intensity in two adapted German BFM paediatric protocols (BFM 90 and NHL 86) was compared in contemporaneously treated adults <50 years with Burkitt lymphoma and B‐cell lymphoma unclassifiable, with features intermediate between diffuse large B‐cell lymphoma and Burkitt lymphoma (collectively referred to as BL). In BFM 90, primary prophylaxis with Granulocyte‐colony‐stimulating factor was used, postinduction treatment was started at granulocytes ≥0.5 × 109/L (≥1.0 × 109/L in NHL 86) with a higher mean methotrexate dose (2.9 g/m2/cycle, n = 23; 1.6 g/m2/cycle in NHL 86, n = 22, P < 0.001). Intervals between consecutive treatment‐cycles were shorter in BFM 90 (P < 0.001) with no additional toxicity. However, the two‐year failure‐free survival with BFM 90 (82%) was similar to that achieved with NHL 86 (72%, P = 0.33). We conclude that BFM 90 enables safe intensification of therapy in young adults with BL compared to NHL 86, but registry‐based studies are required to further evaluate the antineoplastic effects and cost‐effectiveness of the two therapeutic approaches. Am. J. Hematol., 2010. © 2010 Wiley‐Liss, Inc.