bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1 through 8 and Supplementary Figures 1 through 15 from A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk
Authors: Travis Ruth C. , Appleby Paul N. , Martin Richard M. , Holly Jeff M.P. , Albanes Demetrius , Black Amanda , Bueno-de-Mesquita H. Bas , Chan June M. , Chen Chu , Chirlaque Maria-Dolores , Cook Michael B. , Deschasaux Mélanie , Donovan Jenny L. , Ferrucci Luigi , Galan Pilar , Giles Graham G. , Giovannucci Edward L. , Gunter Marc J. , Habel Laurel A. , Hamdy Freddie C. , Helzlsouer Kathy J. , Hercberg Serge , Hoover Robert N. , Janssen Joseph A.M.J.L. , Kaaks Rudolf , Kubo Tatsuhiko , Le Marchand Loic , Metter E. Jeffrey , Mikami Kazuya , Morris Joan K. , Neal David E. , Neuhouser Marian L. , Ozasa Kotaro , Palli Domenico , Platz Elizabeth A. , Pollak Michael N. , Price Alison J. , Roobol Monique J. , Schaefer Catherine , Schenk Jeannette M. , Severi Gianluca , Stampfer Meir J. , Stattin Pär , Tamakoshi Akiko , Tangen Catherine M. , Touvier Mathilde , Wald Nicholas J. , Weiss Noel S. , Ziegler Regina G. , Key Timothy J. , Allen Naomi E.
Published: March 2023

Supplementary tables and figures showing study and assay characteristics, correlations between analytes, and the relationships of the analytes with prostate cancer risk overall, by study and study design, and subdivided by clinical and other characteristics.
Supplementary Materials and Methods from A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk
Authors: Travis Ruth C. , Appleby Paul N. , Martin Richard M. , Holly Jeff M.P. , Albanes Demetrius , Black Amanda , Bueno-de-Mesquita H. Bas , Chan June M. , Chen Chu , Chirlaque Maria-Dolores , Cook Michael B. , Deschasaux Mélanie , Donovan Jenny L. , Ferrucci Luigi , Galan Pilar , Giles Graham G. , Giovannucci Edward L. , Gunter Marc J. , Habel Laurel A. , Hamdy Freddie C. , Helzlsouer Kathy J. , Hercberg Serge , Hoover Robert N. , Janssen Joseph A.M.J.L. , Kaaks Rudolf , Kubo Tatsuhiko , Le Marchand Loic , Metter E. Jeffrey , Mikami Kazuya , Morris Joan K. , Neal David E. , Neuhouser Marian L. , Ozasa Kotaro , Palli Domenico , Platz Elizabeth A. , Pollak Michael N. , Price Alison J. , Roobol Monique J. , Schaefer Catherine , Schenk Jeannette M. , Severi Gianluca , Stampfer Meir J. , Stattin Pär , Tamakoshi Akiko , Tangen Catherine M. , Touvier Mathilde , Wald Nicholas J. , Weiss Noel S. , Ziegler Regina G. , Key Timothy J. , Allen Naomi E.
Published: March 2023

Supplementary material and methods: supplementary information on data collection, statistical analyses, and presentation of results in the figures.
Supplementary Figure legends from An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Authors: Suyama Kimita , Yao Jiahong , Liang Huizhi , Benard Outhiriaradjou , Loudig Olivier D. , Amgalan Dulguun , McKimpson Wendy M. , Phillips Greg R. , Segall Jeffrey , Wang Yihong , Fineberg Susan , Norton Larry , Kitsis Richard N. , Hazan Rachel B.
Published: March 2023

Supplementary Figure legends
Supplemental Figure.1 from An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Authors: Suyama Kimita , Yao Jiahong , Liang Huizhi , Benard Outhiriaradjou , Loudig Olivier D. , Amgalan Dulguun , McKimpson Wendy M. , Phillips Greg R. , Segall Jeffrey , Wang Yihong , Fineberg Susan , Norton Larry , Kitsis Richard N. , Hazan Rachel B.
Published: March 2023

Next generation sequencing of genomic DNA isolated from Akt3/+S472 and Akt3/-S472 knockout cell lines
Supplementary Table S3 from Mutational Landscape of Aggressive Prostate Tumors in African American Men
Authors: Lindquist Karla J. , Paris Pamela L. , Hoffmann Thomas J. , Cardin Niall J. , Kazma Rémi , Mefford Joel A. , Simko Jeffrey P. , Ngo Vy , Chen Yalei , Levin Albert M. , Chitale Dhananjay , Helfand Brian T. , Catalona William J. , Rybicki Benjamin A. , Witte John S.
Published: March 2023

Gene fusions occurring in one or more of the 24 tumors.
Supplementary Table S2 from Mutational Landscape of Aggressive Prostate Tumors in African American Men
Authors: Lindquist Karla J. , Paris Pamela L. , Hoffmann Thomas J. , Cardin Niall J. , Kazma Rémi , Mefford Joel A. , Simko Jeffrey P. , Ngo Vy , Chen Yalei , Levin Albert M. , Chitale Dhananjay , Helfand Brian T. , Catalona William J. , Rybicki Benjamin A. , Witte John S.
Published: March 2023

Individual patient Genomic Evaluators of Metastatic Prostate Cancer (GEMCaP) scores and test results, with and without copy-neutral losses.
Supplemental Figure. 5 from An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Authors: Suyama Kimita , Yao Jiahong , Liang Huizhi , Benard Outhiriaradjou , Loudig Olivier D. , Amgalan Dulguun , McKimpson Wendy M. , Phillips Greg R. , Segall Jeffrey , Wang Yihong , Fineberg Susan , Norton Larry , Kitsis Richard N. , Hazan Rachel B.
Published: March 2023

Akt3/-S472 overexpression in MDA-MB-436 cells suppresses tumor growth by inducing Bim expression and tumor apoptosis
Supplemental Figure. 4 from An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Authors: Suyama Kimita , Yao Jiahong , Liang Huizhi , Benard Outhiriaradjou , Loudig Olivier D. , Amgalan Dulguun , McKimpson Wendy M. , Phillips Greg R. , Segall Jeffrey , Wang Yihong , Fineberg Susan , Norton Larry , Kitsis Richard N. , Hazan Rachel B.
Published: March 2023

Effects of Akt3/-S472 knockout and Akt3/+S472 or Akt1 overexpression on apoptosis
Supplementary Table S1 from Mutational Landscape of Aggressive Prostate Tumors in African American Men
Authors: Lindquist Karla J. , Paris Pamela L. , Hoffmann Thomas J. , Cardin Niall J. , Kazma Rémi , Mefford Joel A. , Simko Jeffrey P. , Ngo Vy , Chen Yalei , Levin Albert M. , Chitale Dhananjay , Helfand Brian T. , Catalona William J. , Rybicki Benjamin A. , Witte John S.
Published: March 2023

The 20 genes with the highest number (N) and percent (%) of tumors impacted by each type of mutation in our data, compared with previous findings in studies of patients with European ancestry.
Supplemental Figure. 3 from An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Authors: Suyama Kimita , Yao Jiahong , Liang Huizhi , Benard Outhiriaradjou , Loudig Olivier D. , Amgalan Dulguun , McKimpson Wendy M. , Phillips Greg R. , Segall Jeffrey , Wang Yihong , Fineberg Susan , Norton Larry , Kitsis Richard N. , Hazan Rachel B.
Published: March 2023

CRISPR mediated knockout of Akt3/-S472 in MDA-MB-231 cells increases mammary tumorigenesis
Supplemental Figure. 2 from An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis
Authors: Suyama Kimita , Yao Jiahong , Liang Huizhi , Benard Outhiriaradjou , Loudig Olivier D. , Amgalan Dulguun , McKimpson Wendy M. , Phillips Greg R. , Segall Jeffrey , Wang Yihong , Fineberg Susan , Norton Larry , Kitsis Richard N. , Hazan Rachel B.
Published: March 2023

Next generation sequencing of genomic DNA isolated from Akt3/+S472 and Akt3/-S472 knockout 3475 tumors
Supplementary information from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

Supplementary experimental procedures and figure legend
Supplementary figure S8 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

Comparison of MMP level in four indicated cell lines after JX06 treatment.
Supplementary figure S7 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

Cysteine 240 is critical for the enzymatic activity of PDK1 in A549 cells.
Supplementary figure S6 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

Chemical structure of biotin-conjugated JX06 and activity in PDK1 inhibition.
Table S2 from Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer
Authors: Raynal Noël J.-M. , Lee Justin T. , Wang Youjun , Beaudry Annie , Madireddi Priyanka , Garriga Judith , Malouf Gabriel G. , Dumont Sarah , Dettman Elisha J. , Gharibyan Vazganush , Ahmed Saira , Chung Woonbok , Childers Wayne E. , Abou-Gharbia Magid , Henry Ryan A. , Andrews Andrew J. , Jelinek Jaroslav , Cui Ying , Baylin Stephen B. , Gill Donald L. , Issa Jean-Pierre J.
Published: March 2023

Table S2. Drug screening results after treatment at 50 ÂµM for 24h
Supplementary figures 1 through 14 from Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer
Authors: Raynal Noël J.-M. , Lee Justin T. , Wang Youjun , Beaudry Annie , Madireddi Priyanka , Garriga Judith , Malouf Gabriel G. , Dumont Sarah , Dettman Elisha J. , Gharibyan Vazganush , Ahmed Saira , Chung Woonbok , Childers Wayne E. , Abou-Gharbia Magid , Henry Ryan A. , Andrews Andrew J. , Jelinek Jaroslav , Cui Ying , Baylin Stephen B. , Gill Donald L. , Issa Jean-Pierre J.
Published: March 2023

Supplementary Figure S1. Drug screening based on the measurement of GFP fluorescence by flow cytometry. Supplementary Figure S2. Dose response curves of GFP reactivation after cardiac glycosides treatment. Supplementary Figure S3. Tumor suppressor genes reactivation after treatment with validated hits. Supplementary Figure S4. Analysis DNA methylation and histone modifications following treatments with validated hits. Supplementary Figure S5. Characterization of Ca2+ fluxes in YB5 and HEK293 cells. Supplementary Figure S6: Tumor suppressor gene reactivation is dependent on CamK activity. Supplementary Figure S7. Promoter occupancy of MeCP2 is decreased after cardiac glycoside treatment. Supplementary Figure S8: Specificity of MeCP2 antibody. Supplementary Figure S9: Assessing the specificity of MeCP2 redistribution after proscillaridin treatment. Supplementary Figure S10. Percentage of YB5 cells expressing GFP after drug treatment is significantly reduced after leptomycin treatment. Supplementary Figure S11. Cell viability assays show that drug induced toxicity is dependent on CamK activity in SW48 colon cancer cell line. Supplementary Figure S12. Cell viability assays show that drug induced toxicity is dependent on CamK activity in K562 leukemia cell line. Supplementary Figure S13. Cell viability assays show that drug induced toxicity is dependent on CamK activity in HL-60 leukemia cell line. Supplementary Figure S14. Scheme describing proposed mechanism of action of newly identified candidate epigenetic drugs.
Supplementary figure S1 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

Thiram inhibits PDK activity in A549 cells.
Supplementary Table S3 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

JX06 activity at 10 μM towards a panel of 323 kinases.
Supplementary Materials and Methods and Supplementary Figure Legends from Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer
Authors: Raynal Noël J.-M. , Lee Justin T. , Wang Youjun , Beaudry Annie , Madireddi Priyanka , Garriga Judith , Malouf Gabriel G. , Dumont Sarah , Dettman Elisha J. , Gharibyan Vazganush , Ahmed Saira , Chung Woonbok , Childers Wayne E. , Abou-Gharbia Magid , Henry Ryan A. , Andrews Andrew J. , Jelinek Jaroslav , Cui Ying , Baylin Stephen B. , Gill Donald L. , Issa Jean-Pierre J.
Published: March 2023

Supplementary Materials and Methods and Supplementary Figure Legends
Supplementary Table S2 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

Activity of JX06 and DCA against PDK1-4.
Supplementary Movie S1 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

A 200 ns molecular dynamic simulation of the open conformation PDK1, in which the sidechain of R286 swung towards different sides.
Supplemental Figure Legend from Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
Authors: Bliss Sarah A. , Sinha Garima , Sandiford Oleta A. , Williams Lisa M. , Engelberth Daniel J. , Guiro Khadidiatou , Isenalumhe Leidy L. , Greco Steven J. , Ayer Seda , Bryan Margarette , Kumar Rakesh , Ponzio Nicholas M. , Rameshwar Pranela
Published: March 2023

Figure legends for the supplemental figures
Movie 2 from Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
Authors: Bliss Sarah A. , Sinha Garima , Sandiford Oleta A. , Williams Lisa M. , Engelberth Daniel J. , Guiro Khadidiatou , Isenalumhe Leidy L. , Greco Steven J. , Ayer Seda , Bryan Margarette , Kumar Rakesh , Ponzio Nicholas M. , Rameshwar Pranela
Published: March 2023

CD63-GFP (green) transfected cells Donor Cells/ Upper well
Supplementary Figure 7 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S7. miR155 is ER-dependent and control HK2 expression.
Supplementary Figure 6 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S6. 2-DG increases MCF7-LTED tumor spheroid invasion in Matrigel.
Supplemental Figure 1 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

Demographic Information of Patient Cohort. A) Age category of patients. B) Cytogenetic category.
Table Legend from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

It has legends for the supplementary tables.
Supplementary table 2 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

Summary of the WGS mapping data
Supplementary Figure S1 from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
Authors: Dermawan Josephine Kam Tai , Hitomi Masahiro , Silver Daniel J. , Wu Qiulian , Sandlesh Poorva , Sloan Andrew E. , Purmal Andrei A. , Gurova Katerina V. , Rich Jeremy N. , Lathia Justin D. , Stark George R. , Venere Monica
Published: March 2023

CBL0137 accumulates in brain tissues.
Supplemental Materials & Methods from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
Authors: Dermawan Josephine Kam Tai , Hitomi Masahiro , Silver Daniel J. , Wu Qiulian , Sandlesh Poorva , Sloan Andrew E. , Purmal Andrei A. , Gurova Katerina V. , Rich Jeremy N. , Lathia Justin D. , Stark George R. , Venere Monica
Published: March 2023

This file contains detailed materials & methods in addition to the materials & methods section in the main text.
Supplementary figure legends from Activation of the MDA-5–IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity
Authors: Yu Xiaofei , Wang Hongxia , Li Xia , Guo Chunqing , Yuan Fang , Fisher Paul B. , Wang Xiang-Yang
Published: March 2023

This file includes figure legends for supplementary figures.
Supplementary Text 1 from Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Authors: Mattina James , MacKinnon Nathalie , Henderson Valerie C. , Fergusson Dean , Kimmelman Jonathan
Published: March 2023

Search strategies for MEDLINE and Embase databases.
Supplementary Figure 2 from Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Authors: Mattina James , MacKinnon Nathalie , Henderson Valerie C. , Fergusson Dean , Kimmelman Jonathan
Published: March 2023

Frequencies of captured time points per experiment. A) The last common time point (LCT) between control and treatment arms and B) the closest time point to day 14 after treatment initiation in the control arm. Filled bars in B) indicate standardized ({plus minus}3 days from day 14) common time points for dose-response analysis.
Supplementary Figure 4 from Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
Authors: Beyranvand Nejad Elham , van der Sluis Tetje C. , van Duikeren Suzanne , Yagita Hideo , Janssen George M. , van Veelen Peter A. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Arens Ramon
Published: March 2023

Categorizations of proteins released upon cisplatin treatment of tumor cells.
Supplementary Table S1 from Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy
Authors: Biktasova Asel K. , Dudimah Duafalia F. , Uzhachenko Roman V. , Park Kyungho , Akhter Anwari , Arasada Rajeswara R. , Evans Jason V. , Novitskiy Sergey V. , Tchekneva Elena E. , Carbone David P. , Shanker Anil , Dikov Mikhail M.
Published: March 2023

Primers used for qRT-PCR in the study.
Supplemetary Figure S4 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

Flow cytometry antibodies are specific.
Supplementary Figure Legends from Phytoestrogen Suppresses Efflux of the Diagnostic Marker Protoporphyrin IX in Lung Carcinoma
Authors: Fujita Hirofumi , Nagakawa Keisuke , Kobuchi Hirotsugu , Ogino Tetsuya , Kondo Yoichi , Inoue Keiji , Shuin Taro , Utsumi Toshihiko , Utsumi Kozo , Sasaki Junzo , Ohuchi Hideyo
Published: March 2023

Legends for Supplementary Figures S1-S2.
Supplemetary Figure S3 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

BPTF does not affect B16F10 cellular morphology or proliferation in vitro but BPTF depleted B16F10 tumors are flat compared to controls.
Supplemetary Dataset S1 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

Microarray data analysis of significant genes in 4T1 tumors harvested from NSG mice. List of primer sequences used in this study.
Supplementary Table S1 from Label-Free Neurosurgical Pathology with Stimulated Raman Imaging
Authors: Lu Fa-Ke , Calligaris David , Olubiyi Olutayo I. , Norton Isaiah , Yang Wenlong , Santagata Sandro , Xie X. Sunney , Golby Alexandra J. , Agar Nathalie Y.R.
Published: March 2023

Diagnostic results for the surgical specimens from surgical cases.
Supplementary Material and Supplementary Figure Legend from Label-Free Neurosurgical Pathology with Stimulated Raman Imaging
Authors: Lu Fa-Ke , Calligaris David , Olubiyi Olutayo I. , Norton Isaiah , Yang Wenlong , Santagata Sandro , Xie X. Sunney , Golby Alexandra J. , Agar Nathalie Y.R.
Published: March 2023

Supplementary dataset information and Supplementary Figure legend.
Supplementary Figures 1 through 7 from SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression
Authors: Santos Juliana Carvalho , Carrasco-Garcia Estefania , Garcia-Puga Mikel , Aldaz Paula , Montes Milagrosa , Fernandez-Reyes Maria , de Oliveira Caroline Candida , Lawrie Charles H , Araúzo-Bravo Marcos J. , Ribeiro Marcelo Lima , Matheu Ander
Published: March 2023

Additional results showing the function of SOX9-beta-catenin in Gastric Cancer
Figure S6 from Restraining Network Response to Targeted Cancer Therapies Improves Efficacy and Reduces Cellular Resistance
Authors: Das Tirtha K. , Esernio Jessica , Cagan Ross L.
Published: March 2023

Figure S6, shows effect of different 'network brake' drug combinations on wildtype flies
Supplementary Figures from Race Disparities in the Contribution of miRNA Isoforms and tRNA-Derived Fragments to Triple-Negative Breast Cancer
Authors: Telonis Aristeidis G. , Rigoutsos Isidore
Published: March 2023

This file contains all Supplementary figures visualizing results from differential expression analyses, network properties and correlation analyses.
Supplementary Figures S1-S9 from Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations
Authors: Rolfs Frank , Huber Marcel , Kuehne Andreas , Kramer Stefan , Haertel Eric , Muzumdar Sukalp , Wagner Johanna , Tanner Yasmine , Böhm Friederike , Smola Sigrun , Zamboni Nicola , Levesque Mitchell P. , Dummer Reinhard , Beer Hans-Dietmar , Hohl Daniel , Werner Sabine , Schäfer Matthias
Published: March 2023

Effect of Nrf2 activation on ROS detoxification and inflammation (S1); Inflammation in TPA-treated K5cre-caNrf2 mice (S2); Development, growth and localization of papillomas in K14- HPV8/K5cre-caNrf2 mice (S3); Inflammation in K14-HPV8 transgenic mice (S4); Metabolomic analysis of epidermis from K14-HPV8/K5crecaNrf2 mice (S5); NF-kB signaling in K5cre-caNrf2 mice (S6); Gene expression and keratinocyte proliferation in K5cre-caNrf2 mice and gene expression in SFN-treated 308 keratinocytes (S7); Keratinocyte proliferation in K14-HPV8 mice and consequence of Nrf2 activation for keratinocyte differentiation (S8); Consequence of Nrf2 activation for keratinocyte apoptosis and ROS production (S9).
Supplementary Figure S7 from Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
Authors: Huang Yu-Hung , Peng Weidan , Furuuchi Narumi , Gerhart Jacquelyn , Rhodes Kelly , Mukherjee Neelanjan , Jimbo Masaya , Gonye Gregory E. , Brody Jonathan R. , Getts Robert C. , Sawicki Janet A.
Published: March 2023

Supplementary Fig. S7. A. Principal component analysis (PCA), and B. Hierarchical Clustering (HCL) Analysis showing distinct difference between transcript profile of siCtrl- and siHuR-transfected A2780 cells. C and D. MA plots of gene expression of 163 genes following transfection of A2780 cells with siHuR and with siCtrl. C. 66 genes were significantly down-regulated and 50 genes were significantly up-regulated when HuR was knocked down. D. 37 significantly down-regulated genes (56%) are direct HuR targets (i.e., HuR binds to their mRNA transcript); 31 significantly up-regulated genes (62%) are direct HuR targets.
Supplementary Figure S5 from Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
Authors: Huang Yu-Hung , Peng Weidan , Furuuchi Narumi , Gerhart Jacquelyn , Rhodes Kelly , Mukherjee Neelanjan , Jimbo Masaya , Gonye Gregory E. , Brody Jonathan R. , Getts Robert C. , Sawicki Janet A.
Published: March 2023

Supplementary Fig. S5. A. 3DNA® dendrimer platform for in vivo tumor-targeted delivery of siHuR. B. Ovarian cancer cell lines, non-tumorigenic human immortalized ovarian epithelial cells (HIO 80 and HIO 120), and murine ID8-Fluc cells express the folate receptor. C. Serum stability. siHuR incubated for 1 hr at 37oC, then assayed on a 10%Tris/Borate/Urea PAGE. Sense strand: 42 bases (modified bases + extension); Antisense strand: 22 bases (modified bases). D. In vitro siHuR knockdown activity. siHuR (13nM) was combined with lipofectamine or targeted 3DNA dendrimer and incubated with A2780 cells overnight in 10% serum-containing medium. Dendrimer plus a scrambled siHuR had no knockdown activity (not shown).
Table S1 from Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells
Authors: Pang Mei-Fong , Siedlik Michael J. , Han Siyang , Stallings-Mann Melody , Radisky Derek C. , Nelson Celeste M.
Published: March 2023

List of primer sequences used for RT-PCR analysis.
Figure S3 from Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells
Authors: Pang Mei-Fong , Siedlik Michael J. , Han Siyang , Stallings-Mann Melody , Radisky Derek C. , Nelson Celeste M.
Published: March 2023

Ectopic expression of ILK induces breast CSC development in MDA-MB-231 human breast cancer cells. (A) qRT-PCR and immunoblotting analysis for ILK and GAPDH in MDA-MB-231 cells transduced with adGFP or adILK. (B) Immunoblotting analysis for phosphorylated and total Akt in MDA-MB-231 cells transduced with adGFP or adILK. Transcript levels of (C) ITGB1, (D) CD44, (E) Nanog, and (F) CD49f in MDA-MB-231 cells transduced with adGFP or adILK and cultured on soft or stiff substrata under normoxia or hypoxia. Phase contrast images and quantification of (G) secondary mammospheres and (H) colonies formed in soft agar by MDA-MB-231 cells transduced with adGFP or adILK. Scale bars, 50 µm. Shown are mean (plus minus) s.e.m. *, P<0.05; **, P<0.01; ***, P<0.001.
Supplementary figure 3 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Authors: Delgado-Calle Jesus , Anderson Judith , Cregor Meloney D. , Hiasa Masahiro , Chirgwin John M. , Carlesso Nadia , Yoneda Toshiyuki , Mohammad Khalid S. , Plotkin Lilian I. , Roodman G. David , Bellido Teresita
Published: March 2023

Supplementary figure 3. Osteocytes regulate cell proliferation and Notch receptor expression in MM cells.
Supplementary figure 1 from Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma
Authors: Delgado-Calle Jesus , Anderson Judith , Cregor Meloney D. , Hiasa Masahiro , Chirgwin John M. , Carlesso Nadia , Yoneda Toshiyuki , Mohammad Khalid S. , Plotkin Lilian I. , Roodman G. David , Bellido Teresita
Published: March 2023

Supplementary figure 1. MM cells induce apoptosis and activate Notch signaling in osteocytes.
SupplementaryFigure 1 from Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation
Authors: Spratt Daniel E. , Evans Michael J. , Davis Brian J. , Doran Michael G. , Lee Man Xia , Shah Neel , Wongvipat John , Carnazza Kathryn E. , Klee George G. , Polkinghorn William , Tindall Donald J. , Lewis Jason S. , Sawyers Charles L.
Published: March 2023

Supplementary Figure 1. In vitro experiments demonstrating increase AR protein level post-radiotherapy; A) Nuclear AR staining, B) 18F-FDHT uptake. C) Isodose distribution of multibeam animal EBRT.
Supplementary Figure 4 from Eritoran Suppresses Colon Cancer by Altering a Functional Balance in Toll-like Receptors That Bind Lipopolysaccharide
Authors: Kuo Wei-Ting , Lee Tsung-Chun , Yu Linda Chia-Hui
Published: March 2023

TLR2-induced signaling pathways and epithelial proliferation are inhibited by eritoran in Caco-2 cells.
Supplementary Figure 3 from Eritoran Suppresses Colon Cancer by Altering a Functional Balance in Toll-like Receptors That Bind Lipopolysaccharide
Authors: Kuo Wei-Ting , Lee Tsung-Chun , Yu Linda Chia-Hui
Published: March 2023

LPS and eritoran trigger apoptosis in HT29 and Caco-2 cells in a TLR4-independent manner.
Supplementary Tables from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: March 2023

LC-MS/MS method details for eicosanoid analysis (Tables S1 and S2); Lipid ID by accurate mass and tandem MS (Tables S3 and S4); Fold change for eicosanoid-related species with MYC activated (Table S5).
Supplementary Methods from Brain-Mimetic 3D Culture Platforms Allow Investigation of Cooperative Effects of Extracellular Matrix Features on Therapeutic Resistance in Glioblastoma
Authors: Xiao Weikun , Zhang Rongyu , Sohrabi Alireza , Ehsanipour Arshia , Sun Songping , Liang Jesse , Walthers Christopher M. , Ta Lisa , Nathanson David A. , Seidlits Stephanie K.
Published: March 2023

Supplementary Methods describing additional information for procedures in manuscript, including hydrogel fabrication, hydrogel sample cryopreservation, lentivirus preparation, mechanical characterization, diffusion, western blotting, and statistics.
Supplemental Figure 4 from JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma
Authors: Chan Tiffany Sin Yu , Hawkins Cynthia , Krieger Jonathan R. , McGlade C. Jane , Huang Annie
Published: March 2023

JPO2 is a LEDGF/p75 responsive gene
Supplemental Figure 3 from JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma
Authors: Chan Tiffany Sin Yu , Hawkins Cynthia , Krieger Jonathan R. , McGlade C. Jane , Huang Annie
Published: March 2023

LEDGF promotes MB cell survival
Supplemental Figure 6: Analysis of spleens from APCMin mice. from HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis
Authors: Lang Michaela , Berry David , Passecker Katharina , Mesteri Ildiko , Bhuju Sabin , Ebner Florian , Sedlyarov Vitaly , Evstatiev Rayko , Dammann Kyle , Loy Alexander , Kuzyk Orest , Kovarik Pavel , Khare Vineeta , Beibel Martin , Roma Guglielmo , Meisner-Kober Nicole , Gasche Christoph
Published: March 2023

MS-444 restores splenic lymphoid follicles and decreases spleen weight in APCMin mice.
Supplementary Figure Legends from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: March 2023

The legends for the supplementary figures 1-7
Supplementary Figure 7. from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: March 2023

Supplementary Figure 7. LDM PTX did not affect the splenic tumor mass in SCID mice xenotransplanted with EGI-1 cells, in vivo.
Suppl Figure 2 from HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Authors: Budina-Kolomets Anna , Webster Marie R. , Leu Julia I-Ju , Jennis Matthew , Krepler Clemens , Guerrini Anastasia , Kossenkov Andrew V. , Xu Wei , Karakousis Giorgos , Schuchter Lynn , Amaravadi Ravi K. , Wu Hong , Yin Xiangfan , Liu Qin , Lu Yiling , Mills Gordon B. , Xu Xiaowei , George Donna L. , Weeraratna Ashani T. , Murphy Maureen E.
Published: March 2023

Kaplan-Meier analysis of data from PrognoScan on the level of HSP70 (A1B) mRNA and survival.
Supplementary figures S1-10 from Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1
Authors: Ann Eun-Jung , Kim Mi-Yeon , Yoon Ji-Hye , Ahn Ji-Seon , Jo Eun-Hye , Lee Hye-Jin , Lee Hyun-Woo , Kang Hyeok-Gu , Choi Dong Wook , Chun Kyung-Hee , Lee Ji Shin , Choi Cheol Yong , Ferrando Adolfo A. , Lee Keesook , Park Hee-Sae
Published: March 2023

Supplementary Figure 1: ADR suppresses Notch1 signaling. Supplementary Figure 2: ADR inhibits the transcriptional activity of Notch1 by inducing HIPK2. Supplementary Figure 3: HIPK2 regulates the Notch1-IC protein stability through proteasomal degradation pathways. Supplementary Figure 4: HIPK2 facilitates Notch1-IC degradation by Fbw7 ubiquitin ligase. Supplementary Figure 5: HIPK2 physically interacts with Notch1-IC. Supplementary Figure 6: HIPK2 phosphorylates Notch1-IC at the T2512 residue. Supplementary Figure 7: HIPK2-mediated downregulation of Notch1-IC suppresses the tumorigenesis of breast cancer. Supplementary Figure 8: Somatic mutations in the CPD motif of Notch1-IC make it resistant to HIPK2. Supplementary Figure 9: Physiological effects of somatic mutations in the CPD motif of Notch1-IC. Supplementary Figure 10: A propose model of Notch1 signaling pathway regulation by HIPK2 in cancer during chemotherapy.
Figure S5 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: March 2023

Effects of KDM5i and DAC on enhancers and de novo super-enhancers
Figure S4 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: March 2023

Differential H3K4me3 enrichment profiling after KDM5i, DAC, or both
Supplementary figure legends from Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1
Authors: Ann Eun-Jung , Kim Mi-Yeon , Yoon Ji-Hye , Ahn Ji-Seon , Jo Eun-Hye , Lee Hye-Jin , Lee Hyun-Woo , Kang Hyeok-Gu , Choi Dong Wook , Chun Kyung-Hee , Lee Ji Shin , Choi Cheol Yong , Ferrando Adolfo A. , Lee Keesook , Park Hee-Sae
Published: March 2023

Supplementary figure legends
Figure S1 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: March 2023

KDM5i increases H3K4 trimethylation alone and in combination with DAC.
Supplementary Tables 2, 3 and 4 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: March 2023

Supplementary Table 2: Clinical-pathological data for colorectal cancer patients used for genomic analysis and validation Supplementary Table 3: Clinical-pathological data for colorectal liver metastasis patients used for genomic analysis and validation Supplementary Table 4: Clinical-pathological data for renal cancer patients used for genomic analysis and validation
Supplementary Figure Legends from Ras Signaling Is a Key Determinant for Metastatic Dissemination and Poor Survival of Luminal Breast Cancer Patients
Authors: Wright Katherine L. , Adams Jessica R. , Liu Jeff C. , Loch Amanda J. , Wong Ruth G. , Jo Christine E.B. , Beck Lauren A. , Santhanam Divya R. , Weiss Laura , Mei Xue , Lane Timothy F. , Koralov Sergei B. , Done Susan J. , Woodgett James R. , Zacksenhaus Eldad , Hu Pingzhao , Egan Sean E.
Published: March 2023

Supplementary Figure Legends 1-5
Supplementary Table S3 from Measurement of Endogenous versus Exogenous Formaldehyde–Induced DNA–Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry
Authors: Lai Yongquan , Yu Rui , Hartwell Hadley J. , Moeller Benjamin C. , Bodnar Wanda M. , Swenberg James A.
Published: March 2023

15 ppm Rat Exposure Results.
Supplementary Table S1 from Measurement of Endogenous versus Exogenous Formaldehyde–Induced DNA–Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry
Authors: Lai Yongquan , Yu Rui , Hartwell Hadley J. , Moeller Benjamin C. , Bodnar Wanda M. , Swenberg James A.
Published: March 2023

Method accuracy and precision.
Table S1 from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: March 2023

Table S1. List of cell lines mentioned/described in this study
Supplemental Table S2 from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: March 2023

PDX list
Supplementary material and methods from Endosialin-Expressing Pericytes Promote Metastatic Dissemination
Authors: Viski Carmen , König Courtney , Kijewska Magdalena , Mogler Carolin , Isacke Clare M. , Augustin Hellmut G.
Published: March 2023

Supplementary material and methods containing protocols for tissue processing, vascular leakage, hypoxia assessment, FACS sort, standard quantitative PCR (qPCR), microarray analysis and Western blot analysis.
Supplementary Table S6 from Molecular Evolution Patterns in Metastatic Lymph Nodes Reflect the Differential Treatment Response of Advanced Primary Lung Cancer
Authors: Um Sang-Won , Joung Je-Gun , Lee Hyun , Kim Hojoong , Kim Kyu-Tae , Park Jinha , Hayes D. Neil , Park Woong-Yang
Published: March 2023

Table S6. Gene expression profile of advanced primary lung cancers.
Supplementary Table S2 from LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1
Authors: Sun Ming , Nie Fengqi , Wang Yunfei , Zhang Zhihong , Hou Jiakai , He Dandan , Xie Min , Xu Lin , De Wei , Wang Zhaoxia , Wang Jun
Published: March 2023

Correlation between HOXA11-AS expression and clinicopathological characteristics of gastric cancer patients (n=85).
Supplementary Figure Legends from Molecular Evolution Patterns in Metastatic Lymph Nodes Reflect the Differential Treatment Response of Advanced Primary Lung Cancer
Authors: Um Sang-Won , Joung Je-Gun , Lee Hyun , Kim Hojoong , Kim Kyu-Tae , Park Jinha , Hayes D. Neil , Park Woong-Yang
Published: March 2023

Figure S1, Figure S2, Figure S3, Figure S4, Figure S5
Supplementary Figure Legends from JNK Pathway Activation Modulates Acquired Resistance to EGFR/HER2–Targeted Therapies
Authors: Manole Simin , Richards Edward J. , Meyer Aaron S.
Published: March 2023

Supplementary Figure Legends
Supplementary Figure 6 from JNK Pathway Activation Modulates Acquired Resistance to EGFR/HER2–Targeted Therapies
Authors: Manole Simin , Richards Edward J. , Meyer Aaron S.
Published: March 2023

Determination of interaction between Mek and JNK inhibition on viability.
Supplementary Table S2 from Splenic Marginal Zone Granulocytes Acquire an Accentuated Neutrophil B-Cell Helper Phenotype in Chronic Lymphocytic Leukemia
Authors: Gätjen Marcel , Brand Franziska , Grau Michael , Gerlach Kerstin , Kettritz Ralph , Westermann Jörg , Anagnostopoulos Ioannis , Lenz Peter , Lenz Georg , Höpken Uta E. , Rehm Armin
Published: March 2023

TOP 25 upregulated in Eμ-Tcl1 stroma by fold change.
Supplementary Information from α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway
Authors: Varzavand Afshin , Hacker Will , Ma Deqin , Gibson-Corley Katherine , Hawayek Maria , Tayh Omar J. , Brown James A. , Henry Michael D. , Stipp Christopher S.
Published: March 2023

RNAi targeting sequences, Supplemental Figure Legends, & Supplemental Figures S1-S11
Table S4 from Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations
Authors: Lu Songjian , Cai Chunhui , Yan Gonghong , Zhou Zhuan , Wan Yong , Chen Vicky , Chen Lujia , Cooper Gregory F. , Obeid Lina M. , Hannun Yusuf A. , Lee Adrian V. , Lu Xinghua
Published: March 2023

An MS Word file contain the genes in a response module annotated GO:0016477 (cell migration) and the literature associated with the genes
Supplementary Figure S1 from Splenic Marginal Zone Granulocytes Acquire an Accentuated Neutrophil B-Cell Helper Phenotype in Chronic Lymphocytic Leukemia
Authors: Gätjen Marcel , Brand Franziska , Grau Michael , Gerlach Kerstin , Kettritz Ralph , Westermann Jörg , Anagnostopoulos Ioannis , Lenz Peter , Lenz Georg , Höpken Uta E. , Rehm Armin
Published: March 2023

Top pathways identified by gene set enrichment analysis.
Supplementary Figure Legends from Splenic Marginal Zone Granulocytes Acquire an Accentuated Neutrophil B-Cell Helper Phenotype in Chronic Lymphocytic Leukemia
Authors: Gätjen Marcel , Brand Franziska , Grau Michael , Gerlach Kerstin , Kettritz Ralph , Westermann Jörg , Anagnostopoulos Ioannis , Lenz Peter , Lenz Georg , Höpken Uta E. , Rehm Armin
Published: March 2023

Legends for Supplementary Figures S1-S6.
Supplementary Table S1 from Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation
Authors: Tech Katherine , Tikunov Andrey P. , Farooq Hamza , Morrissy A. Sorana , Meidinger Jessica , Fish Taylor , Green Sarah C. , Liu Hedi , Li Yisu , Mungall Andrew J. , Moore Richard A. , Ma Yussanne , Jones Steven J.M. , Marra Marco A. , Vander Heiden Matthew G. , Taylor Michael D. , Macdonald Jeffrey M. , Gershon Timothy R.
Published: March 2023

Rates of change of select media metabolites in 24 hour cultures of CGNPs, with and without Pkm2 deletion
Supplemental Table S2 from CIC-DUX4 Induces Small Round Cell Sarcomas Distinct from Ewing Sarcoma
Authors: Yoshimoto Toyoki , Tanaka Miwa , Homme Mizuki , Yamazaki Yukari , Takazawa Yutaka , Antonescu Cristina R. , Nakamura Takuro
Published: March 2023

The list of siRNA
Supplementary Figure S4 from Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation
Authors: Tech Katherine , Tikunov Andrey P. , Farooq Hamza , Morrissy A. Sorana , Meidinger Jessica , Fish Taylor , Green Sarah C. , Liu Hedi , Li Yisu , Mungall Andrew J. , Moore Richard A. , Ma Yussanne , Jones Steven J.M. , Marra Marco A. , Vander Heiden Matthew G. , Taylor Michael D. , Macdonald Jeffrey M. , Gershon Timothy R.
Published: March 2023

Immunofluorescence for PKM1 and PCNA demonstrates that PKM1+ cells within medulloblastomas are PCNA-.
Supplementary Figure S2 from Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation
Authors: Tech Katherine , Tikunov Andrey P. , Farooq Hamza , Morrissy A. Sorana , Meidinger Jessica , Fish Taylor , Green Sarah C. , Liu Hedi , Li Yisu , Mungall Andrew J. , Moore Richard A. , Ma Yussanne , Jones Steven J.M. , Marra Marco A. , Vander Heiden Matthew G. , Taylor Michael D. , Macdonald Jeffrey M. , Gershon Timothy R.
Published: March 2023

Documentation of germline Pkm2 deletion, showing A) change in the size of products genotyping PCR, B) genomic sequence showing absence of exon 10, and C) complete absence of PKM2 expression in all tissues within the brain, and intact PKM1 expression.
Supplementary Figure S6 from The p53/p21 Complex Regulates Cancer Cell Invasion and Apoptosis by Targeting Bcl-2 Family Proteins
Authors: Kim Eun Mi , Jung Chan-Hun , Kim Jongdoo , Hwang Sang-Gu , Park Jong Kuk , Um Hong-Duck
Published: March 2023

Comparison of H1299, H460, H1975 lung cancer cells
Tables S1, S2, S4, S8, S9 from MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
Authors: Reinhardt Julia , Landsberg Jennifer , Schmid-Burgk Jonathan L. , Ramis Bartomeu Bibiloni , Bald Tobias , Glodde Nicole , Lopez-Ramos Dorys , Young Arabella , Ngiow Shin Foong , Nettersheim Daniel , Schorle Hubert , Quast Thomas , Kolanus Waldemar , Schadendorf Dirk , Long Georgina V. , Madore Jason , Scolyer Richard A. , Ribas Antoni , Smyth Mark J. , Tumeh Paul C. , Tüting Thomas , Hölzel Michael
Published: March 2023

Supplemental Table S1. DNA oligos used in this study Supplemental Table S2. Characteristics of patients with primary melanomas and cutaneous melanoma metastasis (Bonn cohorts). Supplemental Table S4. List of transcription factors binding in NT5E based on ENCODE ChIP-seq data. Supplemental Table S8. Changes of CD73 IHC score in melanoma patients from the UCLA cohort under pembrolizumab treatment (anti-PD-1). Supplemental Table S9. Characteristics and changes of CD73 expressions of melanomas from patients of the Sydney cohort treated with nivolumab or pembrolizumab (anti PD-1).