bluuebunny/crossref_metadata_2025 huggingface dataset:
Stakeholders’ Perception on the Impacts of Tourism on Mass Destinations: The Case of Seville
Authors: Haro Aragú Marina , García-Mestanza Josefa , Caballero-Galeote Lidia
Published: August 2021

Stakeholders’ participation is critical to implementing sustainable development models at mass tourism destinations. Through the application of a mixed methodology focused on the collection, processing, and analysis of quantitative and qualitative data, this study analyzes the perception of residents, accommodation establishments, the academic community, and tourists in the city of Seville, since they are the possible agents of change in the current model. In addition, the study of perceptions provides information to extract a definition of mass tourism for these groups. Findings show that the majority of those surveyed affirm the presence of mass tourism in the city, and choose carrying capacity as an instrument to predict this type of tourism. We also show that, while mass tourism is not a sustainable model, its transformation is possible. As a consequence, the tourists’, destination’s and local population’s tolerance limits would determine the size and direction of the tourist impact.
Past Experience and Willingness to Pay: A Comparative Examination of Destination Loyalty in Two National Parks, China
Authors: Yuan Jianqiong , Li Jingjing , Deng Jinyang , Arbogast Douglas
Published: August 2021

The long-term sustainability of China’s national parks depends on the appropriate use and management of park resources and the provision of positive experience opportunities for tourists. While past experience, in terms of frequency of visits to the same destination and behavioral intention measured as willingness to revisit/recommend, have been extensively examined in a typical destination loyalty model using structural equation modeling (SEM), past experience with other destinations and willingness to pay (WTP), another form of behavioral intention, have received less attention from researchers. This paper, for the first time, simultaneously examined these two types of past experience and WTP using both second-order and first-order SEMs, based on data collected from two national parks in China. Results show that, while frequency of visits had no significant impacts on attribute satisfaction (AS) nor on overall satisfaction (OS), previous experience with other destinations significantly influenced AS, which, in turn, significantly predicted OS. While OS significantly and consistently predicted visitors’ intentions to revisit/recommend for both samples, its impact on WTP was significant for one sample, but not for the other. This suggests that asymmetric beliefs in destination loyalty may exist, depending on how and where behavioral intention was measured. The study endorses norm theory in studying destination satisfaction.
How Ecosystem Services Can Strengthen the Regeneration Policies for Monumental Olive Groves Destroyed by Xylella fastidiosa Bacterium in a Peri-Urban Area
Authors: Semeraro Teodoro , Gatto Elisa , Buccolieri Riccardo , Catanzaro Valentina , De Bellis Luigi , Cotrozzi Lorenzo , Lorenzini Giacomo , Vergine Marzia , Luvisi Andrea
Published: August 2021

The Apulian Region (Italy) is a socio-ecological system shaped by the millennial co-evolution between human actions and ecological processes. It is characterized by monumental olive groves protected from Regional Law 14/2007 for the cultural value of the landscape, currently threatened by the spread of a devastating phytopathogen, the bacteria Xylella fastidiosa. The aim of this paper is to apply landscape resilience analysis focusing on ecosystem services to understand the potential effects and trade-offs of regeneration policies in a peri-urban area characterized by monumental olive groves land cover. The study involved land-cover and land-use analysis, supported by a survey on the inhabitants and an ecosystem services analysis. The results showed a mismatch between the agroecosystem and the social and economic use linked to leisure or hospitality. The study area was defined as a peri-urban landscape characterized by tourist use. From the interviews of the users, the cultural heritage of olive groves seems linked to the presence of olive trees like a status quo of the landscape and olive oil productions. The culture aspect could thus be preserved by changing the type of olive trees. In addition, the analysis showed that the microclimate could be preserved and enhanced in terms of air temperature and thermal comfort, by replacing the olive trees with varieties resistant to Xylella, such as cv. Leccino. Therefore, regeneration policies that promote replacing dead olive groves with new olive trees could be efficient to stimulate social components of the landscape and improve the resilience of ecosystem services in peri-urban areas in the interest of the cultural heritage of the users and benefits that they provide. An ecosystem services analysis at a local scale could be a strategy for an integrated regenerate approach between land-use and land-cover with social, ecological, and economic evolutions vision orientated to a sustainable and desirable future.
From Comparative and Statistical Assessments of Liveability and Health Conditions of Districts in Hong Kong towards Future City Development
Authors: Chi Yan , Mak Hugo
Published: August 2021

Liveability is an indispensable component in future city planning and is practically linked with the health status of individuals and communities. However, there was nor comprehensive and universal district-level framework for assessing liveability due to geospatial and social discrepancies among different countries. In this study, using Hong Kong, a highly dense and international city as an example, the Liveability and Health Index (LHI-HK) consisting of 30 indicators was established, with 21 of them related to education, economy, housing, walkability/transport, environment, and health facilities aspects, while the health conditions of citizens in individual districts were examined by other 9 indicators. Respective scoring allocation was determined by statistical reasoning, and was applied to quantify the connections between liveability and health among the 18 districts of Hong Kong in both 2016 and 2019. Temporal changes of spatial features could be traced by this quantitative framework, and obvious correlations between liveability and health were attained, with R values of 0.496 and 0.518 in 2016 and 2019, and corresponding slopes of 0.80 and 0.88, respectively. Based on the statistical results, it was found that Sai Kung and Kwun Tong are the most and the least liveable district of Hong Kong in 2019. The LHI-HK index was well-validated by renowned AARP liveability index and The California Healthy Places Index (HPI), with R values of 0.90 and 0.70, and the potential uncertainties due to data projection were less than 2.5% for all districts, which implicates its relevancy and appropriateness in conducting similar spatial assessments in international cities. Further, both favorable and unfavorable spatial arrangements of each of the 3 district types in Hong Kong were identified, namely residential, commercial, and industrial districts. This opens new windows in enhancing liveability and health status within communities, with the aim of promoting the sustainability of cities in the long run.
Sociodemographic Characteristics and Leisure Participation through the Perspective of Leisure Inequalities in Later Life
Authors: Yoon Hyejin , Kim Eunhee , Kim Chulwon
Published: August 2021

This study examined the relationship between sociodemographic characteristics and leisure involvement in various meaningful activities under the political economy of aging and life course. The stepwise multiple and ordinal regression model revealed that the individual factors of older adults were significantly associated with leisure involvement: age (younger adults), gender (men), education level (higher education), perceived economic satisfaction (higher satisfaction with their financial condition), and perceived health (higher satisfaction with their health) variables were significantly related to more frequent participation in domestic leisure travel. Additionally, gender and education level were associated with leisure-time exercise; the four variables (gender, education level, economic activity, and perceived financial satisfaction) were related to leisure-time social activities. Contrary to our expectation, older adults who are older and with lower education were more likely to participate in volunteering activities. The results suggested that older adults’ sociodemographic characteristics play an essential role in leisure behavior. The extent to which these characteristics affect leisure participation varies with different types of activities and cultural contexts.
Promotion of Social Innovation through Fab Labs. The Case of ProteinLab UTEM in Chile
Authors: Valenzuela-Zubiaur Macarena , Torres-Bustos Héctor , Arroyo-Vázquez Mónica , Ferrer-Gisbert Pablo
Published: August 2021

Fab Labs as manufacturing laboratories that stimulate innovation and collaboration are nowadays proliferating within universities. Given the new social challenges, framed within the Sustainable Development Goals (SDG), we formulate the following research question: Are Fab Labs an effective tool for the promotion of social innovation from universities? To answer this question, a mixed analysis has been carried out focusing on the case of ProteinLab UTEM. The approach aims to generate a model for the promotion of social innovation from universities through Fab Labs, linking the quadruple helix actors. The objective of this model is to show how Fab Labs can become an effective instrument to promote social innovation from universities. The contribution of this article lies in linking Fab Labs with social innovation through the university’s third mission. Our approach considers Fab Labs as an instrument for the development of social innovations within the university, which contribute, through the third mission, to the social and sustainable development of its environment. As a result of this research, a model is presented for the development of social innovation from universities through Fab Labs. Our research concludes that Fab Labs are an effective instrument for the promotion of social innovation from universities.
Recent Developments in Microbial Electrolysis Cell-Based Biohydrogen Production Utilizing Wastewater as a Feedstock
Authors: Dange Pooja , Pandit Soumya , Jadhav Dipak , Shanmugam Poojhaa , Gupta Piyush Kumar , Kumar Sanjay , Kumar Manu , Yang Yung-Hun , Bhatia Shashi Kant
Published: August 2021

Carbon constraints, as well as the growing hazard of greenhouse gas emissions, have accelerated research into all possible renewable energy and fuel sources. Microbial electrolysis cells (MECs), a novel technology able to convert soluble organic matter into energy such as hydrogen gas, represent the most recent breakthrough. While research into energy recovery from wastewater using microbial electrolysis cells is fascinating and a carbon-neutral technology that is still mostly limited to lab-scale applications, much more work on improving the function of microbial electrolysis cells would be required to expand their use in many of these applications. The present limiting issues for effective scaling up of the manufacturing process include the high manufacturing costs of microbial electrolysis cells, their high internal resistance and methanogenesis, and membrane/cathode biofouling. This paper examines the evolution of microbial electrolysis cell technology in terms of hydrogen yield, operational aspects that impact total hydrogen output in optimization studies, and important information on the efficiency of the processes. Moreover, life-cycle assessment of MEC technology in comparison to other technologies has been discussed. According to the results, MEC is at technology readiness level (TRL) 5, which means that it is ready for industrial development, and, according to the techno-economics, it may be commercialized soon due to its carbon-neutral qualities.
Arbuscular Mycorrhizal Fungus Stimulates Young Field-Grown Nectarine Trees
Authors: Conesa María R. , López-Martínez Lidia , Conejero Wenceslao , Vera Juan , Ruiz-Sánchez María Carmen
Published: August 2021

Although mycorrhizae applications have been widely used to improve the establishment and growth of agricultural crops, there have been no studies on their application in field-grown nectarine trees. In this work, a commercial arbuscular mycorrhizal fungus (AMF; Glomus iranicum var. tenuihypharum) was applied by means of fertigation to inoculate young “Flariba” nectarine trees grown in south-eastern Spain to evaluate its effect on plant water status, and vegetative and reproductive growth. Using minirhizotrons to measure the root dynamics over a complete growing season, revealed that AMF substantially increased root growth (51% increase compared with untreated trees), while no changes in plant water status or canopy development were noted. The productive response improved in inoculated trees, as demonstrated by a significantly higher yield, fruit size, number of fruits per tree and greater crop load efficiency values than in untreated trees. Given that the same amount of irrigation solution was applied in both treatments, the irrigation water use efficiency increased by 19.5% in AMF compared with untreated trees. The findings of this study suggest that a simple inoculation of AMF can be considered a good practice in semi-arid agro-systems to firmly establish efficient young nectarine trees and enhance their adaptation to field conditions.
Pharmaceutical Product Modularization as a Mass Customization Strategy to Increase Patient Benefit Cost-Efficiently
Authors: Siiskonen Maria , Malmqvist Johan , Folestad Staffan
Published: August 2021

Customized pharmaceutical products aim to comply with the individual needs of a patient to enhance the treatment outcome. The current pharmaceutical production paradigm is, however, dominated by mass production, where the pharmaceutical products embrace a one-size-fits-all design with a low possibility of treatment optimization to patient needs. This production paradigm is not designed or intended for customized pharmaceutical products and operating this production context for customized pharmaceutical products is argued to be cost-inefficient. To address this challenge of inefficient production of customized pharmaceutical products, this study proposes an approach to modular pharmaceutical product design. As a mass customization strategy, product modularization enables serving customers with customized products cost-efficiently. The proposed modular pharmaceutical products integrate three product design requirements originating from patient needs: a scalable dose strength, a flexible target release profile, and a scalable treatment size. An approach to assess the value of these product designs is presented, by means of proposing three benefit metrics complying with respective design requirements and a cost metric assessing the cost of producing these modular pharmaceutical product designs. Results suggest that pharmaceutical product modularization can, by keeping the number of produced components low, substantially increase the external product variety and, hence, enhance the treatment outcome of patients. Furthermore, results indicate that the achieved benefit for the patient through product modularization increases beyond additional costs arising during production. However, a careful modularization must be performed to optimize the tradeoff between the increased benefit and cost.
Comparative Analysis of Machine Learning Methods to Predict Growth of F. sporotrichioides and Production of T-2 and HT-2 Toxins in Treatments with Ethylene-Vinyl Alcohol Films Containing Pure Components of Essential Oils
Authors: Mateo Eva María , Gómez José Vicente , Tarazona Andrea , García-Esparza María Ángeles , Mateo Fernando
Published: August 2021

The efficacy of ethylene-vinyl alcohol copolymer films (EVOH) incorporating the essential oil components cinnamaldehyde (CINHO), citral (CIT), isoeugenol (IEG), or linalool (LIN) to control growth rate (GR) and production of T-2 and HT-2 toxins by Fusarium sporotrichioides cultured on oat grains under different temperature (28, 20, and 15 °C) and water activity (aw) (0.99 and 0.96) regimes was assayed. GR in controls/treatments usually increased with increasing temperature, regardless of aw, but no significant differences concerning aw were found. Toxin production decreased with increasing temperature. The effectiveness of films to control fungal GR and toxin production was as follows: EVOH-CIT > EVOH-CINHO > EVOH-IEG > EVOH-LIN. With few exceptions, effective doses of EVOH-CIT, EVOH-CINHO, and EVOH-IEG films to reduce/inhibit GR by 50%, 90%, and 100% (ED50, ED90, and ED100) ranged from 515 to 3330 µg/culture in Petri dish (25 g oat grains) depending on film type, aw, and temperature. ED90 and ED100 of EVOH-LIN were >3330 µg/fungal culture. The potential of several machine learning (ML) methods to predict F. sporotrichioides GR and T-2 and HT-2 toxin production under the assayed conditions was comparatively analyzed. XGBoost and random forest attained the best performance, support vector machine and neural network ranked third or fourth depending on the output, while multiple linear regression proved to be the worst.
Exploring the Multifunctional Roles of Odontoglossum Ringspot Virus P126 in Facilitating Cymbidium Mosaic Virus Cell-to-Cell Movement during Mixed Infection
Authors: Lee Shu-Chuan , Pai Hsuan , Huang Ying-Wen , He Meng-Hsun , Song Yun-Lin , Kuo Song-Yi , Chang Wen-Chi , Hsu Yau-Heiu , Lin Na-Sheng
Published: August 2021

Synergistic interactions among viruses, hosts and/or transmission vectors during mixed infection can alter viral titers, symptom severity or host range. Viral suppressors of RNA silencing (VSRs) are considered one of such factors contributing to synergistic responses. Odontoglossum ringspot virus (ORSV) and cymbidium mosaic virus (CymMV), which are two of the most significant orchid viruses, exhibit synergistic symptom intensification in Phalaenopsis orchids with unilaterally enhanced CymMV movement by ORSV. In order to reveal the underlying mechanisms, we generated infectious cDNA clones of ORSV and CymMV isolated from Phalaenopsis that exerted similar unilateral synergism in both Phalaenopsis orchid and Nicotiana benthamiana. Moreover, we show that the ORSV replicase P126 is a VSR. Mutagenesis analysis revealed that mutation of the methionine in the carboxyl terminus of ORSV P126 abolished ORSV replication even though some P126 mutants preserved VSR activity, indicating that the VSR function of P126 alone is not sufficient for viral replication. Thus, P126 functions in both ORSV replication and as a VSR. Furthermore, P126 expression enhanced cell-to-cell movement and viral titers of CymMV in infected Phalaenopsis flowers and N. benthamiana leaves. Taking together, both the VSR and protein function of P126 might be prerequisites for unilaterally enhancing CymMV cell-to-cell movement by ORSV.
Evaluation of Streptococcus uberis Surface Proteins as Vaccine Antigens to Control S. uberis Mastitis in Dairy Cows
Authors: Kerro Dego Oudessa , Almeida Raul , Ivey Susan , Agga Getahun E.
Published: August 2021

There is no effective vaccine against Streptococcus uberis mastitis in dairy cows. Objectives of this study were (1) to extract S. uberis surface proteins (SUSP) and determine immunoreactivity in vitro and (2) immunogenicity and efficacy in vivo. SUSP was extracted from S. uberis, and their immunoreactivity was tested by western blot. In total, 26 Jersey dairy cows were randomly divided into four groups. Groups 1, 2, and 3 were vaccinated subcutaneously with 4 mg, 1 mg, and 100 μg of SUSP, respectively, with Freund’s incomplete adjuvant. Group 4 (control) was injected with placebo. S. uberis UT888 was infused into two contralateral quarters of each cow during early lactation. Somatic cell count (SCC), bacteria count in milk, and mastitis were monitored. Our results show that SUSP contains multiple protein bands, that ranged from 10 to 100 kDa. All vaccinates showed an increased anti-SUSP IgG antibody. The SCC of all experimentally infected quarters increased after challenge but slightly decreased after day 3 with no significant difference among groups. Milk bacterial count was significantly (p < 0.05) reduced in high and medium doses vaccinated groups than low and control groups. In conclusion, SUSP vaccine is immunogenic and showed a promising efficacy to control bovine S. uberis mastitis.
Cardiorespiratory Effects of Three Infusion Doses of Adenosine in Conscious Goats: A Preliminary Study
Authors: Salah Eman , Abouelfetouh Mahmoud , Englar Ryane , Ding Mingxing , Ding Yi
Published: August 2021

Adenosine (AD) has been implicated in human healthcare as an endogenous signaling nucleotide in both physiologic and pathologic states. The effects of AD on cardiorespiratory parameters in ruminants has not yet been studied. The objective of this study was to evaluate the cardiac and respiratory changes that resulted from an intravenous AD infusion in goats. Six clinically healthy adult goats weighing 28 ± 2 kg were randomly assigned to one of four treatments in a crossover design with a seven day washout period. The goats received a 0.9 % saline solution (SAL treatment) and three AD treatments (AD 50, 100 and 200) intravenously at a dose rate of 50, 100 and 200 μg/kg/min. Cardiorespiratory and key cardiac parameters were measured before the treatment (baseline), during the infusion (dInf) and at 1, 3, 5 and 10 min after each infusion was discontinued. The AD 100 produced a significant increase in HR (p = 0.001) and the AD 200 resulted in significant rises in HR (p = 0.006) and RR (p = 0.001) compared with the baseline. This study concluded that the AD infusion could trigger an increase in HR and RR in a dose-dependent manner in healthy goats.
Evaluation of Water Resources Carrying Capacity in Guiyang City
Authors: Ren Li , Gao Jiachen , Song Shuping , Li Zhuoman , Ni Jianjun
Published: August 2021

Based on the situation of Guiyang’s water resources, society, economy, ecology, etc., a comprehensive evaluation index system of Guiyang’s water resources carrying capacity is established by selecting appropriate indexes. Based on the analytic hierarchy process (AHP) and the entropy method, an evaluation model of Guiyang’s water resources carrying capacity is constructed. The results showed that the comprehensive evaluation value of water resources carrying capacity in Guiyang City increased by nearly 53% from 2009 to 2018, and the regulation and control force of water resources carrying capacity and water resources carrying pressure showed an upward trend. Within ten years, the total comprehensive evaluation value of Guiyang is 0.4503—close to H2 level—and the membership degree of evaluation results over the years to H2 is greater than that of H1 and H3. H1, H2, and H3 are the three standard grades of water resources carrying capacity index, and the degree of carrying capacity represented is decreasing in turn. This indicated that at this stage, water resources can maintain the rapid development of the social economy, and that there is still some development potential. The research results have certain reference value for Guiyang’s development and utilization of water resources.
Evaluation of Humanitarian Supply Chain Resilience in Flood Disaster
Authors: Xu Wenping , Xiong Shu , Proverbs David , Zhong Zhi
Published: August 2021

Frequent natural hazards such as flooding and the devastating consequences of severe events make the humanitarian supply chain particularly important in alleviating the suffering of those communities impacted by such events. However, the ambiguity of information and the different goals of stakeholders demand that the humanitarian supply chain must be resilient. This research adopts the use of literature review and expert opinions to identify the indicators that affect the resilience of the humanitarian supply chain using the flood event in Hechuan District, China in 2020 as an example. Based on the combination of fuzzy Decision-making Trial and Evaluation Laboratory and Analytic Network Process (fuzzy-DEMATEL-ANP), the interrelationships between the indicators and the weights of each indicator are calculated. The research results indicate that decision-makers in the humanitarian supply chain should vigorously coordinate the cooperation among stakeholders, ensure the effective transmission of information, and formulate forward-looking strategic plans. At the same time, these key decision makers should also be aware of the need to adjust their strategies at different stages of the flooding event in order to achieve a flexible humanitarian supply chain that responds to the varying demands over the course of a flooding event. The results of this study will help professionals involved in humanitarian supply chains to develop strategies and plans to become more resilient thus helping to reduce losses from natural hazards such as floods.
PREPARATION OF FUTURE PSYCHOLOGISTS FOR THE PREVENTION OF CYBERBULLYING IN ONLINE COMMUNICATION OF ADOLESCENTS
Authors: Khomenko Z.
Published: August 2021

The article is devoted to the challenges of modern online communication of people, which in recent years has spread around the world. The modern Internet has become a wide, integrating environment, full of useful and interesting things and at the same time rich in irritation, aggression, persecution. Both the positive and negative aspects of the network are constantly evolving, adding to the number of online dangers. One such threat is cyberbullying, which often takes place on the platforms of various social networks, is a real danger to the social and mental comfort of people, especially adolescents, who are often unable to distinguish between virtual and real features of communication. One of the effective means of preventing such threats is the acquisition by future psychologists of knowledge about the types of cyberbullying, its essence, the specification of the time spent by adolescents in a virtual environment, the risks of computer addiction, and so on. Emphasis is placed on mastering by future specialists domestic and foreign methods of recognizing various phenomena of cyberbullying, working with individual psychological factors, especially adolescents, preventing manifestations of aggression, cruelty, emotional imbalance in children’s communication in networks. The article, based on foreign and domestic scientific sources and research methods, identifies and describes the factors influencing future psychologists to prevent and alleviate the effects of cyberbullying in online communication of adolescents, recognizing the phenomena of cyber aggression, increasing resilience, educating emotional intelligence and communicative intelligence. This will provide professionals with a significant component of their competence.
MONITORING OF GENERAL SECONDARY EDUCATION QUALITY: DIAGNOSTIC AND COMPETENCY SCIENTIFIC POSITION
Authors: Hritsenko L. , Lysenko L.
Published: August 2021

The article clarifies the scientific basis of monitoring the quality of education on the basis of diagnostic and competence understanding of the possibilities of systematic research of this process in general secondary education institutions. The analysis of sources and publications made it possible to identify the importance of the problem of monitoring the quality of education for the theory of management of general secondary and higher education, considering this category as political, managerial, pedagogical. Clarification of the leading characteristics of the quality of education (multifaceted, multilevel end results, polychronicity, multi-subjectivity, multi-criteria, uncertainty in assessments, invariance and variability) in the works of Ukrainian and foreign authors led to the goal - outlining in research the scientific basis of quality monitoring on the basis of diagnostic-competence understanding of the possibilities of systematic research of this process in the institutions of general secondary school. The functions of monitoring the quality of education are characterized: activating, informational, corrective, formative, diagnostic and analytical, modeling and management, prognostic; the algorithm of their realization offered by T. Lukina and A. Belkin is chosen. The diagnostic and competence specifics of control methods in the system of quality monitoring of general secondary education are determined. One of the management tools and elements of the system is defined as quality monitoring, which is recommended to be understood as “supervision, tracking, observation; testing or measurement at specified time intervals to control and regulate processes ”has the status of a study rather than an empirical collection of material, and is complex, systemic in nature. The conclusion on specificity of quality control of education which provides: check - revealing of a condition of formation of components of competence is carried out; assessment - measurement and conditional reflection of this condition in the form of a level of quantitative or qualitative assessment; accounting - recording results in the form of summary tables. It is recommended to reflect the process of education quality assessment in a certain scale, which systematically takes into account the data obtained during the current assessment, testing, performance of tests and practical tasks, exams, ranking, etc.
Idiopathic Hypokalemia in Lupus Nephritis: A Newly Recognized Entity
Authors: Adomako Emmanuel A. , Bilal Saira , Liu Yu-lun , Malik Ayesha , Van Buren Peter N. , Shastri Shani , Sambandam Kamalanathan K.
Published: August 2021

Key Points

Hypokalemia may occur in patients with lupus nephritis in the absence of renal tubular acidosis (RTA) or other known causes.

Patients with lupus nephritis and idiopathic hypokalemia have a distinct pattern of markers of autoimmunity.

Clinically evident RTA in lupus nephritis exhibits a distinct pattern of markers of autoimmunity.

Background

Various causes of hypokalemia (HK) from renal potassium wasting, including distal renal tubular acidosis (RTA), have been described in lupus nephritis (LN). We report a phenomenon of otherwise unexplained HK among a population with LN.

Methods

From our population of 403 patients with LN, we identified a cohort of 20 patients with idiopathic HK, defined by serum potassium <3.5 mmol/L without any apparent explanation. This cohort is compared with 90 LN controls (CON) and ten patients with LN with distal RTA from the same population.

Results

The patients with HK had lower median serum potassium compared with CON and RTA subjects (3.26 versus 4.00 versus 3.75 mmol/L, respectively; P<0.001). The median serum bicarbonate was normal in HK and CON, but low in RTA (26.0 versus 25.0 versus 19.4 mmol/L; P<0.001). The median urine pH was abnormally high only in the RTA group (6.00 versus 6.25 versus 6.67; P=0.012). The median serum magnesium was modestly lower in HK compared with the CON and RTA groups (1.73 versus 2.00 versus 1.85 mg/dl; P=0.002). Although both HK and RTA showed a higher rate of seropositivity than CON for anti-Ro/SSA (79% and 80% versus 37%, respectively; P<0.001), only HK revealed a higher rate of seropositivity than CON for anti-RNP (84% versus 42%; P=0.003) and only RTA showed a higher rate of seropositivity than CON for anti-La/SSB (40% versus 12%; P=0.05).

Conclusions

A syndrome of idiopathic HK was revealed in 20 out of 403 (5%) of patients within our LN population, and proved to be distinct from the RTA that occurs in LN. Furthermore, it was associated with a distinct pattern of autoantibodies. We speculate that idiopathic HK is the result of a novel target of autoimmunity in LN, affecting renal tubular potassium transport.
O USO DA CIRURGIA ROBÓTICA E DA VIDEOTORACOSCOPIA NO TRATAMENTO DO CÂNCER DE PULMÃO: UMA REVISÃO SISTEMÁTICA
Authors: Rodrigues Vinícius dos Santos Sá , Gomes Elisa Mileni de Sá , Aguiar Larissa Carneiro Barros , Ruas Lucas Medeiros , Gomes Lucas Mendes , Francisco Manoela Amaral , de Castro Maria Fernanda Souza , Godoy Mariana Cristina Silva , de Oliveira Romildo Rodrigues , Flores Samuel de Sena , Botelho Túlio Esteves Tormin
Published: August 2021

Introdução: O câncer de pulmão é a neoplasia com maior número de mortes anualmente. Assim, recentemente, implementaram-se novas intervenções como a cirurgia torácica vídeo assistida e a cirurgia robótica. Objetivo:  Apresentar as diferenças entre os desfechos da VATS e da RATS para o tratamento de câncer de pulmão. Metódos: Artigos publicados entre 2016 e 2021, incluindo estudos originais, ensaios clínicos, estudos retrospectivos e caso-controle foram selecionados. As bases de dados Medline, SciELO, LILACS, Ovid e Cochrane foram consultadas na busca. Foram encontrados 32 artigos e, após aplicação dos critérios de inclusão e exclusão, 12 estudos foram lidos na íntegra; 4 foram elegíveis para essa revisão sistemática. Resultados e discussão: O tamanho da amostra dos artigos incluídos na revisão variou de 10 a 470 pacientes, sendo a faixa etária  entre 55 e 68 anos em todos os estudos analisados retrospectivamente. Os seguintes desfechos foram comparados: complicações perioperatórias, tempo de duração de internação hospitalar, tempo de duração da cirurgia, taxa de conversão e taxa de mortalidade. A única diferença significativa encontrada foi uma menor taxa de conversão na RATS, por vantagens técnicas. Conclusão: Apesar da menor taxa de conversão na RATS, em geral, os desfechos não apresentaram diferença significativa.
Pt/CNT Micro-Nanorobots Driven by Glucose Catalytic Decomposition
Authors: Wang Hao , Kan Jiacheng , Zhang Xin , Gu Chenyi , Yang Zhan
Published: August 2021

Swimming micro-nanorobots have attracted researchers’ interest in potential medical applications on target therapy, biosensor, drug carrier, and others. At present, the experimental setting of the swimming micro-nanorobots was mainly studied in pure water or H
2
O
2
solution. This paper presents a micro-nanorobot that applied glucose in human body fluid as driving fuel. Based on the catalytic properties of the anode and cathode materials of the glucose fuel cell, platinum (Pt) and carbon nanotube (CNT) were selected as the anode and cathode materials, respectively, for the micro-nanorobot. The innovative design adopted the method of template electrochemical and chemical vapor deposition to manufacture the Pt/CNT micro-nanorobot structure. Both the scanning electron microscope (SEM) and transmission electron microscope (TEM) were employed to observe the morphology of the sample, and its elements were analyzed by energy-dispersive X-ray spectroscopy (EDX). Through a large number of experiments in a glucose solution and according to Stoker’s law of viscous force and Newton’s second law, we calculated the driving force of the fabricated micro-nanorobot. It was concluded that the structure of the Pt/CNT micro-nanorobot satisfied the required characteristics of both biocompatibility and motion.
Research Subjects about the Comparison of British and Japanese Scholarship of Islam
Authors: Tuoheti Alimu
Published: August 2021

All around the world, how we interpret the Islamic world objectively and accurately is an important topic for concerned scholars all over the world. Britain has a history of Islamic Studies for more than 400 years, and the current standard and research paradigm of Islamic Studies in the UK deserves our attention. It is of great practical significance for us to thoroughly and systematically understand the contemporary Islamic world in this special historical stage of great turbulence, great differentiation, and great change, and then comprehensively grasp the regional issues of Islam and build a discourse system of Islamic research with modern characteristics. In the past 30 years, Japanese academic circles have not been able to keep abreast of the development of Islamic Studies in the UK, let alone go deep into the frontier field of cultural communication. Based on this, through literature analysis and field visits, this Project intends to overview of the current situation of Islamic Studies in Britain and Japan, focusing on the two main paradigms of its cultural studies, and then to explore the how these academic efforts can benefit and impact the discourse construction of Islamic Studies in Japan and UK.
Digitalization and its Rapid Impact on Savings Banks in Germany
Authors: Giebe Carsten , Schulz Kevin
Published: August 2021

The German banking industry is facing major challenges due to digitalization. The digital transformation is significantly influenced by technological progress, tighter regulation and low-interest phases. The market entry of fintechs and changing customer behaviour is also a reality. To meet the challenge of the digitalization and to to reduce costs, savings banks are increasingly turning to mergers, staff cuts and branch closures. The purpose of this research is to investigate the impact of digitalization on German savings banks. Through an explorative literature review, scientific sources and real KPIs of savings banks in Germany were used. The impact of digitalization on savings banks in the period 1999 – 2018 was investigated using the study situation and the analysis of key business figures. The aim is to answer whether the cost-cutting actions of savings banks are justified from an economic point of view based on the KPIs operating result, cost-income ratio and return on equity. In recent years, it has become clear that German banks lack a clear strategy. The results may be of interest to researchers dealing with the digital transformation of savings banks in Germany.
Jesus Christus – Repräsentant Gottes
Authors: Bernhardt Reinhold
Published: August 2021

Wie kann man die Person und die Bedeutung Jesu Christi in einer religiös pluralen Welt verstehen? Reinhold Bernhardt entfaltet eine Christologie im Spannungsfeld von biblischem Grundtext und gegenwärtigem Kontext – ohne Relativierung und ohne Verabsolutierung. Jesus Christus ist der Repräsentant Gottes bei den Menschen und der Repräsentant der Menschen bei Gott. Er vergegenwärtigt den Heilswillen Gottes, der aber über den Repräsentanten hinausreicht. Die Göttlichkeit Jesu besteht nicht in seiner göttlichen Natur, sondern in der Besonderheit seiner Gottesbeziehung, seiner einzigartigen Vertrautheit mit dem Wesen, dem Willen und der Wirklichkeit Gottes. In der Auseinandersetzung mit fünf Entwürfen aus der deutschsprachigen und amerikanischen Theologie des 19. und 20. Jahrhunderts (Schleiermacher, Biedermann, Ritschl, Ogden und Haight) wird das Profil dieser «Repräsentationschristologie» geschärft. Ein innovativer und gut verständlicher Beitrag nicht nur zu einer Theologie der Religionen, sondern ebenso zum Kern des christlichen Glaubens.
Studi Arus Jenuh pada Persimpangan dengan Bundaran
Authors: Purba Widiawati , Melasari Jihan , Prabowo Helmi
Published: August 2021

Permasalahan transportasi sangat sering terjadi seperti kemacetan, polusi udara, kecelakaan, antrian maupun tundaan biasa di jumpai dengan tingkat kualitas yang rendah maupun tinggi. Kota padang adalah salah satu kota diSumatra Barat dan merupakan kota industri dan pariwisata yang banyak menarik peminat penduduk di kota lain yang ikut berkunjung. Jln. Khatib Sulaiman pada simpang empat bundaran merupakan salah satu simpang yang terletak di simpang presiden. Arus lalu lintas yang melalui simpang tersebut tersebut cukup padat pada waktu-waktu jam sibuk. Sehingga terdapat aktivitas padat di jalan ini seperti angkutan umum yang berhenti untuk naik dan menurunkan penumpang, kendaraan yang parkir di badan jalan serta kendaraan yang keluar masuk disamping jalan darilingkungan sekitar simpang. Penelitian ini bertujuan untuk menganalisis atau mengevaluasi arus jenuh pada simpang empat bundaran Khatib Sulaiman saat ini dengan memberikan alternatif pemecahan masalah yang tepat pada simpang tersebut. Sifat dari penelitian ini adalah analisis, penelitian dilakukan satu minggu penuh dari hari senin sampai minggu dan di mulai pada pukul 07:00-09:00, 12:00-14:00, sampai 16:00-18:00. Dari hasil penelitian yangdilakukan maka didapat nilai kapasitas sebagai berikut: Kapasitas (C) = 1921,01 SMP/jam, Penelitian kapasitas jalan Teuku Umar kurang memadai disebabkan tingkat pelayanan jalan (LOS) mencapai 2,3 dimana dengan nilaitersebut sering terjadi kemacetan dan antrian panjang dengan tingkat pelayanan F dan berdasarkan banyak jumlah pengguna kendaraan Di Jl Khatib Sulaiman arah simpang DPRD pada jam sibuk yaitu hari senin jam 16.00 – 18.00 adalah sebesar 3291,3.
Pengaruh Kompensasi dan Beban Kerja Terhadap Kepuasan Kerja dalam Meningkatkan Kinerja Karyawan PT. Kepsindo Indra Utama Padang
Authors: Wahyuni Rika , Irfani Hadi
Published: August 2021

This study aims to analyze how compensation and workload effect on job satisfaction; compensation and workload effect on employee performance; and job satisfaction effect on employee’s performance at the PT. Kepsindo Indra Utama Padang. Type of this research is quantitative research. The samples are 80 employees of the PT. Kepsindo Indra Utama Padang using saturation sampling technique. Methods of data collection is using questionnaire. This research is using path analysis. The results showed that: 1) compensation has positive and significant impact on job satisfaction, 2) workload have negative and significant impact on job satisfaction, 3) compensation has positive and significant impact on employee performance, 4) workload has negative and significant impact on employee performance, and 5) job satisfaction has positive and significant impact on employee  performance. The results showed that the direct path of job compensation has the most powerful effect on employee performance demonstrated by having the highest impact regression coefficient (dominant) amounted to 0,664.
Faktor-Faktor yang Mempengaruhi Kecemasan Ibu Hamil Primigravida Trisemster III dalam Menghadapi Persalinan di Puskesmas Batu Aji Kota Batam Tahun 2018
Authors: Prameswari Yuditia
Published: August 2021

The first pregnancy (primigravida) is a very important event for women because in addition to feeling happy and meaningful, it is also possible to feel anxiety and fear, when preparing for labour, especially entering the third trimester. Anxiety and fear can cause pain and can lead to decreased uterine contractions, so the labor process will last longer. The purpose of this study was to determine the factors that influencing the anxiety of Primigravida Trimester III pregnant women, in dealing with childbirth at the Batu Aji Health Center in Batam in 2018. This study was analytical with a cross sectional approach conducted in May - September 2018 at the Batu Aji City Health Center Batam. Data from the Batam City Health Office (Dinas Kesehatan Kota Batam) in 2017 shows that the highest coverage of pregnant women visits is in the Batu Aji Health Center with 4073 pregnant women. The sampling technique is total sampling with a sample size of 40 pregnant women. This study used the HRS-A questionnaire and checklist sheet. The researcher revealed that knowledge, occupational status, age were the factors to be studied. Data analysis using Chi-Square and the results obtained p = 0,000 <0,05, which indicates a significant correlation between the knowledge of pregnant women and anxiety of pregnant women, p = 0,155 <0,05, no correlation between working status and the anxiety of pregnant women, p = 0.571 ≥ 0.05 and there is a correlation between the age of the mother and the anxiety of pregnant women, p = 0.004 <0.050. There were 23 pregnant women who experienced low anxiety (57.7%), 35 people had good knowledge about pregnancy (87.5%). Advice for health workers is to be able to improve the quality of care for pregnant women to reduce anxiety experienced by mothers, and pregnant women should use the health care facilities that have been provided.
Hubungan Antara Regulasi Diri dengan Prokrastinasi Akademik pada Mahasiswa Korps Sukarela Palang Merah Indonesia (KSR PMI) di Universitas Negeri Padang
Authors: Nisva Lidia , Okfrima Ria
Published: August 2021

This research was carried out to PMI KSR students in Padang State. This study aims to see whether there is a relationship between Self Regulation and Academic Procrastination at Students of the Voluntary Corps of the Indonesian Red Cross (KSR PMI) at Padang State University. The population in this study was the 2014 PMI KSR students who were still active in the organization. The research subjects used Purposif sampling technique. Sampling technique with certain considerations. Measuring instrument used is the self-regulation skla researchers collated based on the theory proposed in 2014 and Procrastination Purnawasari the researchers collated based on the theory proposed by Gufron 2010. Data analysis methods were used to test the hypothesis in this research is by using correlation product moment(person)which shows that r = -0,378 with a value of p = 0.016, meaning that there is a significant relationship between the relationship between self-regulation and the 2014 KSR PMI student procrastination at Padang State University. Means the research hypothesis is accepted. The effective contribution of the self-regulation variable with the 2014 PMR KSR student academic procrastination in Padang is 14%.
Hubungan Antara Lingkungan Kerja Fisik dengan Kesehatan dan Keselamatan Kerja pada Pasukan Kuning di Kota Padang
Authors: Fikri Harry Theozard , Putri Rahma Dwi
Published: August 2021

This study aims to see whether there is a relationship between the Physical Work Environment and Occupational Health and Safety in the Yellow Forces in Padang City, with a population of 283 people. The sampling technique used is a simple random sampling technique, namely the technique of taking sample members from the population carried out randomly regardless of the strata that exist within the population. The number of samples in this study were 62 people. from 0.314 to 0.908 and the reliability coefficient is 0.931. While the coefficient of validity on the occupational health and safety scale moves from 0.322 to 0.764 and the reliability coefficient is 0.942. Hypothesis test results show the magnitude of the reliability coefficient of 0.479 with a significant level of p = 0,000 meaning that it can be concluded that there is a significant relationship between the work environment and occupational health and safety, with a positive direction. This means that if the research has a high work environment then work health and safety will also be high. Likewise, if you have a low physical work environment, eating health and safety will also be low. The effective contribution Environment with of the Physical Work Occupational Health and Safety in the Yellow Forces in the City of Padang is 23%.
Kehangatan Hubungan dengan Orang Tua, Pengasuh dan Teman dengan Sindrome Depresi pada Remaja Panti Asuhan di Jakarta
Authors: Sulaiman Nesi
Published: August 2021

Depression is a mental health problem caused by multifactors and is common in adolescents. Adolescents who live in orphanages are considered vulnerable to the appearance of depression. Even so, adolescents who live in orphanages in Jakarta generally still have parents so they can establish a warmth relationship as protection against depression syndrome. In addition to parents, adolescents who live at the Orphanage also establish warmth relationships with friends and caregivers. This research was conducted to find out how the warmth of adolescent relationships with parents, caregivers and friends with depression syndrome among adolescents in orphanages. This study was conducted in 402 adolescents (male: 179; female: 223; M: 14.88) in 20 orphanages in Jakarta. The results of the study show the warmth of relationships with mothers, fathers, caregivers and friends in adolescents at the middle level and symptoms of depression at low levels. Furthermore, this study found that only the warmth of the relationship with the father correlated with depression syndrome.