bluuebunny/crossref_metadata_2025 huggingface dataset:
Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development
Authors: Xiao Yue , Chen Jiehui , Yang Suming , Sun Honghua , Xie Lele , Li Jinsong , Jing Naihe , Zhu Xueliang
Published: December 2022

Early embryonic development depends on proper utilization and clearance of maternal transcriptomes. How these processes are spatiotemporally regulated remains unclear. Here we show that nuclear RNA‐binding protein Rbm14 and maternal mRNAs co‐phase separate into cytoplasmic condensates to facilitate vertebrate blastula‐to‐gastrula development. In zebrafish, Rbm14 condensates were highly abundant in blastomeres and markedly reduced after prominent activation of zygotic transcription. They concentrated at spindle poles by associating with centrosomal γ‐tubulin puncta and displayed mainly asymmetric divisions with a global symmetry across embryonic midline in 8‐ and 16‐cell embryos. Their formation was dose‐dependently stimulated by m6A, but repressed by m5C modification of the maternal mRNA. Furthermore, deadenylase Parn co‐phase separated with these condensates, and this was required for deadenylation of the mRNAs in early blastomeres. Depletion of Rbm14 impaired embryonic cell differentiations and full activations of the zygotic genome in both zebrafish and mouse and resulted in developmental arrest at the blastula stage. Our results suggest that cytoplasmic Rbm14 condensate formation regulates early embryogenesis by facilitating deadenylation, protection, and mitotic allocation of m6A‐modified maternal mRNAs, and by releasing the poly(A)‐less transcripts upon regulated disassembly to allow their re‐polyadenylation and translation or clearance.
Legal Protection for Witnesses and Victims of Crimes of Terrorism
Authors: Umam Muhammad Miftahul , Arifin Ridwan
Published: December 2022

Terrorism is a form of extraordinary crime that is an enemy to mankind. Terrorism throughout history has been a very frightening specter. This is inseparable from the impact it causes, the loss is not only property, life, physical, psychological, but also creates an atmosphere of terror that grips all levels of society. Therefore, victims and witnesses of acts of terrorism must receive protection in view of these various things. As a state of law, Indonesia has established several laws and regulations governing the protection of victims of terrorism, including Law no. 15 of 2003, as amended by Law no. 5 of 2018 concerning Amendments to Law Number 15 of 2003 concerning Stipulation of Government Regulations in Lieu of Law Number 1 of 2002 concerning Eradication of Criminal Acts of Terrorism into Law, Law no. 13 of 2006, as amended by Law no. 31 of 2014 concerning Amendments to Law Number 13 of 2006 concerning the Protection of Witnesses and Victims and other regulations. With the existence of a legal footing that regulates, it is hoped that it can provide protection for witnesses and victims of acts of terrorism. In addition, various parties also play a role in the recovery of victims from acts of terrorism, including; police institutions, social services, hospitals, Kesbangpol, PMI, NGOs, LPSK, and so on. However, witnesses and victims of criminal acts of terrorism in obtaining legal protection through the above regulations are not always in line with the existing reality. This is inseparable from the existence of inhibiting factors, both in the aspect of legal substance, legal structure, and legal culture components.
De novo purely prostatic large-cell neuroendocrine carcinoma with thyroid and adrenal metastases
Authors: Karvounis Evangelos , Zoupas Ioannis , Bantouna Dimitra , Paparodis Rodis D , Efthymiadou Roxani , Ioakimidou Christina , Panopoulos Christos
Published: December 2022

Large-cell neuroendocrine carcinoma (LCNEC) is a rare neuroendocrine prostatic malignancy. It usually arises after androgen deprivation therapy (ADT), while de novo cases are even more infrequent, with only six cases described. The patient was a 78-year-old man with no history of ADT who presented with cervical lymphadenopathy. Diagnostic approaches included PET/CT, MRI, CT scans, ultrasonography, biopsies, and cytological and immunohistochemical evaluations. Results showed a poorly differentiated carcinoma in the thyroid gland accompanied by cervical lymph node enlargement. Thyroid surgery revealed LCNEC metastasis to the thyroid gland. Additional metastases were identified in both the adrenal glands. Despite appropriate treatment, the patient died of the disease. De novo LCNEC of the prostate is a rare, highly aggressive tumor with a poor prognosis. It is resistant to most therapeutic agents, has a high metastatic potential, and is usually diagnosed at an advanced stage. Further studies are required to characterize this tumor.

Learning points

De novo LCNECs of the prostate gland can metastasize almost anywhere in the body, including the thyroid and adrenal glands.

LCNECs of the prostate are usually associated with androgen-depriving therapy, but de novo cases are also notable and should be accounted for.

Further studies are required to fully understand and treat LCNECs more effectively.
GÖÇMEN KAÇAKÇILIKĞINDA KARASULARINDAN AÇIK DENİZLERE SAHİL GÜVENLİĞİN MÜDAHALE HAKLARI
Authors: GÖZÜGÜZELLİ Emete
Published: December 2022

Son yıllarda Karadeniz, Akdeniz, Afrika ve Güney Doğu Asya gibi dünyanın belirli bölgelerinde mevcut olan çatışma ve istikrarsızlık, deniz yoluyla düzensiz göç olgusunu şiddetlendirmiştir. Deniz yoluyla insan kaçakçılığı aynı zamanda en hızlı büyüyen ulusötesi organize suçlardan birini oluşturmaktadır. Üç tarafı denizlerle çevrili olan Türkiye Cumhuriyeti’nin coğrafi olarak bulunduğu konumdan ötürü göçmen krizi ile ilgilenmek durumundadır. Türkiye kendi sahil güvenliğini Sahil Güvenlik Komutanlığı nezdinde korumaktadır. Türkiye’nin göçmen kaçakçılığı söz konusu olduğunda bu kaçakçılık karşısında hangi hukuksal müdahale haklarının var olduğunu ortaya koyması önemli bir meseledir. Çalışmada karasularından hareketle açık denizlere kaçan Türk bayraklı bir gemiye müdahale edilmesinde sahil güvenliğin deniz hukukundan kaynaklı temaül haline gelen hukuksal hakları bu çalışmada incelenmiştir.
La geopolítica detrás de la pandemia del COVID-19. Reseña del libro Coronavirus Politics: The comparative Politics and Policy of COVID-19
Authors: Zamora-Steller Sandy
Published: December 2022

The book Coronavirus Politics: The comparative Politics and Policy of COVID-19  analyzes how elements of power are directly related to the measures implemented by governments to face the pandemic of COVID-19. And how these elements conditioned the development of the pandemic in different regions worldwide. Then, the book uses individual study cases for the different geographical regions, this allows for contextualized reflections where people living in the studied regions deepen on the reactions of their governments.
Aportes para despatriarcalizar la educación: experiencias de formación feminista en pandemia
Authors: Bonavitta Paola , Gili Diez Valeria , Coseani Daniela
Published: December 2022

This work derived from the course “Feminist Knowledge and Practices in experiences of curricular integration” taught by two work teams located in Argentina: GAGES, belonging to the National University of San Juan (UNSJ), and El Telar, from the National University of Cordoba (UNC). This course was taught online through the Moodle platform via the Distance Education System (SIED) of the UNSJ, during May 2021, and was aimed at teachers and researchers of both institutions, with synchronous and asynchronous meetings distributed in five modules.The study started considering the university and its territory as a space for disputes, practices, and meanings. This article seeks to recognize, from teaching, extension, and research practices, the commitment to feminism as a way to decolonize higher education institutions.The questions guiding the paper are: Is it possible to depatriarchalize and decolonize universities? What role do university teachers and researchers play in the spaces we inhabit/transit? How do we contribute to stopping reproducing violence/inequality?The answers to these questions supposed to address the reflections collected in the course-workshop by the 51 people who attended the meeting. Then, students’ comments and proposals were analyzed.
Effects of surface lamination process parameters on medium density fiberboard (MDF) properties
Authors: Özlüsoylu İsmail , İstek Abdullah
Published: December 2022

Medium density fiberboard (MDF) is widely utilized in furniture production. Most MDF in such applications has a surface laminate layer. The lamination process improves the physical and mechanical properties of the boards. The temperature, press time, and pressure values applied during the lamination process affect such properties. In this work, the lamination process was carried out using a constant temperature (180 °C), four different press times (18, 20, 22, and 24 s), and three different pressures (25, 30, and 35 kg/cm2). The raw weight of the decor paper was 90 g/m2 and UF and MF glues were used in its production. The properties of the laminated panels were then determined for each variation. In general, the water absorption and thickness swelling properties were improved at the lower pressure and higher press times. The internal bonding strength exhibited a linear change at different press times depending on increasing pressure values, whereas the changes in the bending strength and modulus of elasticity in bending were not statistically significant. It was concluded that the BS increased with rising pressure in the short-term lamination process and that the effect of the pressure on the BS declined with increasing press time.
Review of the current state of application of wood defect recognition technology
Authors: Chen Yutang , Sun Chengshuo , Ren Zirui , Na Bin
Published: December 2022

Wood utilisation is an important factor affecting production costs, but the combined utilisation rate of wood is generally only 50 to 70%. During the production process, the rejection scheme of wood defects is one of the most important factors affecting the wood yield. This paper provides an overview of the main wood defects affecting wood quality, introduces techniques for detecting and identifying wood defects using different technologies, highlights the more widely used image recognition-based wood surface defect identification methods, and presents three advanced wood defect detection and identification equipment. In view of the relatively fixed wood defect recognition requirements in wood processing production, it is proposed that wood defect recognition technology should be further developed toward deep learning to improve the accuracy and efficiency of wood defect recognition.
Flushed but not forgotten: The rising costs and opportunities of disposable wet wipes
Authors: Hadley Tilda , Hickey Kate , Lix Kelsi , Sharma Shivani , Berretta Tyler , Navessin Titichai
Published: December 2022

The increasing popularity of single-use wet wipes across a variety of applications has caused environmental and economic challenges. Due to their convenience and low cost, disposable nonwoven wipes have become a necessity in the lives of many. However, consumers rarely consider the end-of-life of these items. Despite efforts from stakeholders, including wipes manufacturers and wastewater experts, there is frequent confusion among consumers regarding appropriate disposal. Many consumers flush wipes that are not compatible with municipal sewer systems, causing considerable damage. Additionally, wipes have poor environmental outcomes, as they often contain non-renewable plastics or are unable to biodegrade under disposal conditions. Previously, the wet wipes industry was projected to grow an average of 6% between 2021 and 2025; however, the use of these disposable items is projected to be much higher due to the COVID-19 pandemic. This paper reviews the market, key challenges, and technical properties of single-use nonwoven wipes. An emphasis is placed on the unique properties and associated challenges of flushable wipes. With strong market demands, consumers are unlikely to abandon single-use wipes, and therefore innovative solutions are required to solve the main environmental and technical challenges associated with flushable and non-flushable wipes.
Visuomeninio saugumo neapibrėžtumas: NATO mažųjų valstybių atvejis
Authors:   , Bladaitė Neringa
Published: December 2022

Indeterminacy of societal security: the case of NATO's small states
Evolution of dislocation line shape in multicomponent alloys under loading
Authors:   I. M. Frantsevich Institute for Problems of Materials Science of NAS of Ukraine, Lugovy M. I. , Verbylo D. G. ,   I. M. Frantsevich Institute for Problems of Materials Science of NAS of Ukraine, Brodnikovskyy M. P. ,   I. M. Frantsevich Institute for Problems of Materials Science of NAS of Ukraine
Published: December 2022

The evolution of the dislocation line shape in a multicomponent alloy CrCoNiFeMn under loading was investigated by the method of discrete dislocation dynamics. It was found in a numerical experiment that the best approximation for the shape of the average bulge of the dislocation line would be a sinusoidal shape rather than a parabolic or arc shape. The equilibrium form of dislocation at zero load fits well into a band with a width of three correlation lengths of the short-wave component of the shear stress field created by dissolved atoms in the glide plane. In this case the dislocation line waviness on the scale of the correlation length of the long-wave component is not observed. It has been found that dislocation segments can overcome internal stress barriers with external applied stress assistance. This is an irreversible process of new equilibrium bulges formation. One of these bulges becomes nonequilibrium, increases and releases the dislocation from the initial fixation at a critical stress, which can be conditionally considered to be the yield strength. The external stress, which assists to the dislocation segments to overcome the internal stress barriers, can to some extent compensate for the short-wave component of the shear stress field. Then, as the numerical experiment shows, the dislocation line waviness on the scale of the correlation length of the long-wave component will be activated. Thus, the two components of the shear stress field affect the shape of the dislocation line separately and sequentially with increasing external load. Keywords: shear stresses, solid solution, glide plane, dislocation.
Obstrüktif uyku apne sendromu olan kadın ve erkeklerde respiratuar kas fonksiyonu, solunum fonksiyonları ve egzersiz kapasitesinin incelenmesi
Authors: ÇAKARTAŞ Şahveren , İNAL İNCE Deniz , KAYMAKAMZADE Bahar , SAĞLAM Melda , RASMUSSEN Finn
Published: December 2022

Amaç: Bu çalışmada Obstrüktif Uyku Apne Sendromu (OUAS) tanısı almış kadın ve erkek hastalarda elektromiyografik respiratuar kas fonksiyonu, solunum kas kuvveti, solunum fonksiyonları ve egzersiz kapasitenin karşılaştırılması amaçlandı.
Yöntem: Çalışmaya 19 OUAS olgusu (yaş ortalaması=54,68±13,15 yıl, 10 E, 9 K) dahil edildi. Polisomnografi (PSG) değerlendirmesinden apne/hipopne indeksi (AHİ) ve en düşük oksijen satürasyonu (SpO2) değerleri kaydedildi. Solunum fonksiyon testinde birinci saniyedeki zorlu ekspirasyon volümü (FEV1) ve zorlu vital kapasite (FVC) değerleri kaydedildi. Maksimal inspiratuar basınç (MIP) ve maksimal ekspiratuar basınç (MEP) ölçüldü. Respiratuar kas fonksiyonu, diyafragma yüzeyel elektromiyografi (EMGdi) ve sternoclediomasteoid elektromiyografi (EMGscm) ölçümleri ile değerlendirildi. Altı dakika yürüme testi (6DYT) ve Pittsburgh Uyku Kalitesi İndeksi (PUKİ) uygulandı.
Bulgular: Erkek OUAS hastalarının FEV1, FVC, %MIP, MEP, EMGdi, EMGscm ve 6DYT mesafesi değerleri kadın olgulardan daha yüksekti (p<0,05). Erkeklerde AHİ ve uyku sırasındaki en düşük SpO2 değeri ilişkiydi (r=-0,659, p=0,038). Kadın OUAS olgularında AHİ, en düşük SpO2 değeri (r=-0,678) ve MIP değeri (r=0,904) ile anlamlı ilişki gösterdi (p<0,05). Kadınlarda MIP ve 6DYT mesafesi arasında anlamlı bir korelasyon vardı (r=-0,762, p=0,017).
Sonuç: Kadın OUAS olgularında solunum fonksiyonları solunum kas kuvveti ve diyafragmatik fonksiyon ve egzersiz kapasitesi erkek olgulara göre daha fazla etkilenmektedir. OUAS’ta diyafragmatik fonksiyon değerlendirilerek tedavi programının yönlendirilmesine katkı sağlayabilir.
discurso militar
Authors: Ghiraldelli Paula Ramos , Soares Thiago Barbosa
Published: December 2022

O presente artigo busca analisar discursivamente a propaganda brasileira de alistamento militar (2022). Seu intuito é verificar as concepções ideológicas expressas discursivamente e o modo como os mecanismos discursivos operam em prol de reforçar um posicionamento político-ideológico governamental, uma vez que os enunciados produzidos pelo exército se constituem como Aparelhos Ideológicos do Estado (ALTHUSSER, 1980), representando os ideais estatais. O objeto em questão é considerado propaganda, de acordo com a definição proposta por Costa e Mendes (2012), que descrevem tais formas enunciativas como fornecedoras de um objeto ideológico, ou seja, referem-se à propagação de ideias, principalmente políticas. Para a análise, foram utilizados os conceitos de cena da enunciação e ethos discursivo – respectivamente o espaço discursivo e a imagem de si do enunciador (MAINGUENEAU, 1996, 2004, 2008, 2015). Através do exame dessas construções na propaganda, foram constatados os aspectos culturais, sociais e ideológicos sob os quais esses elementos se constituem. Tanto a cena quanto o ethos do objeto apresentam destacadamente a neutralidade e o silenciamento como mecanismos persuasivos, vinculados a uma intenção não conflituosa do enunciador. O objetivo, com isso, é resgatar a boa imagem do exército aos olhos brasileiros, por meio da construção de uma enunciação “positiva” sobre o país no quesito da violência interna e do racismo, promovendo o país e o trabalho do exército como locais interligados em que a igualdade, a democracia e a justiça insurgem. Entretanto, tais características não significam a representação integral da realidade do país, uma vez que a violência interna e o racismo estão amplamente presentes no Brasil e são silenciados pela propaganda.
Masculinidades rentáveis na ficção brasileira de temática homoerótica
Authors: Nascimento Dorinaldo dos Santos
Published: December 2022

No âmbito da ficção brasileira de temática homoerótica, é recorrente encontramos personagens masculinos que alugam seus corpos (ou partes dele) adotando, estrategicamente, corporeidades, gestualidades e discursividades prototípicas da masculinidade hegemônica (CONNELL, 1997). Nessa ficção, também emergem, refletindo o peso sociocultural da heteronormatividade, personagens homossexuais pagantes pelo sexo que buscam como fantasia sexual um corpo-prostituto2 moldado por uma masculinidade rústica, agressiva e “suja”. Desse modo, o propósito, neste trabalho, é realizar uma leitura crítica envolvendo um conjunto de narrativas ficcionais (contos e romances) – presente na literatura brasileira de temática homoerótica –, problematizando-se nelas a monetização da masculinidade hegemônica pelos sujeitos que se prostituem. Para tanto, o aporte teórico-crítico buscou uma interlocução entre crítica literária e eixos de discussão fundamentados em pesquisas e estudos etnográficos (Antropologia, Sociologia e Psicologia Social) que abarcam aspectos acerca da prostituição masculina vinculados ao ethos da homossexualidade.
Administering Justice — Without State Courts1
Authors: Tárkány-Szücs Ernő
Published: December 2022

Many of the drafts and notes of Ernő Szücs Tárkány are in manuscript, and they can offer valuable clues for European legal ethnography. One of them is a manuscript by Tárkány Szücs, both in Hungarian and English, in the Archives of the Institute of Ethnology of the Research Centre for the Humanities, dated 1982 and titled Administering Justice — without State Courts, which has been awaiting publication for forty years. This study is an important milestone, as it demonstrates, based on a broad international perspective, that even in a field that was monopolized by the state very early on, such as administering justice, legal customs have survived to a great extent; and that legal ethnographic approaches make it possible to arrive at valid conclusions of practical importance through an expert comparison of legal phenomena that are distinct in time and space but have common characteristics. The English-language version of the study is being published verbatim (first publication).
Legal Folklore among the Petty Nobility of the Káli Basin
Authors: Gelencsér József
Published: December 2022

In the Káli Basin in the Balaton Uplands, four of the eight settlements bordering each other (Balatonhenye, Köveskál, Kővágóörs, Monoszló) were inhabited by petty nobles belonging to the gentry, living in curial villages, with a great deal of autonomy, self-governance, and within the framework of their established legal norms and legal customs. They lost most of their privileges in the mid-19th century, but some of their old and new legal customs survived until the mid-20th century. The study reviews part of their extensive living conditions, essentially from the last third of the 18th century. The way of life in this region, known for high-quality grapes and livestock, has changed a lot in the more than 200 years. The study describes each typical component of this life in view of the provisions of established law, customary law, and legal customs. Considering legal distinctions, it addresses secular and ecclesiastical administration, legal relationships regarding vineyards, certain work customs, succession laws, and the vestiges of petty nobility that survived into the 20th century. The role of certain legal customs contrary or complementary to the laws (contra legem, praeter legem) is also mentioned. The study provides a brief overview, or at least a taste, of the special (petty noble) legal folklore of the Káli Basin, which is rich in legal customs.
Ernő Tárkány Szücs's Legal Ethnographic Research and International Ethnography (1967–1994)
Authors: Bognár Szabina
Published: December 2022

In 1967, Ernő Tárkány Szücs published his article summarizing the results and tasks of European legal ethnography in the columns of Ethnologica Europeana in Paris (under the title Results and Task of Legal Ethnology in Europe). With this, he revived an important tradition of Hungarian legal ethnography: Károly Tagányi published his summary of international research history in German in 1922 (Lebende Rechtsgewohnheiten und ihre Sammlung in Ungarn. Ungarische Bibliothek. Für das Ungarische Institut an der Universität Berlin. Erste Reihe. Vereinigung wissenschaftlicher Verleger. Berlin und Leipzig). At the time of the publication of Ernő Tárkány Szücs's article, he was working as a ministerial official, but in Hungarian academic life he took a backseat. At the same time, however, he was in constant contact with several European representatives of legal folklore. As soon as he had the opportunity, Tárkány Szücs opened up to international scholarship, and became not only an active participant but also a prime mover of the international discourse on legal folk custom research. His recognition was indicated by the fact that throughout Europe, not only his studies published in various world languages but also his papers exclusively in Hungarian were often cited. Although the science policy in his country was not able to integrate the specifically interdisciplinary scientific research of Ernő Tárkány Szücs, or only haltingly, his international recognition was unquestionable all along.
Hungarian Legal Ethnography in Light of the Oeuvre of Ernő Tárkány Szücs
Authors: Nagy Janka Teodóra
Published: December 2022

Ernő Tárkány Szücs (1921–1984) was a researcher who created a synthesis of Hungarian legal ethnography, a mediator of his results for European legal ethnographic research, and his scientific work is still an essential part of Hungarian research history. During the most intensive period (1939–1948) of Hungarian legal folklore research — which was delayed compared to European legal customs research — he became a lawyer and a researcher of Hungarian legal ethnography along with legal history professor György Bónis from Kolozsvár (nowdays Cluj-Napoca). Although in the next phase of his life (1950–1975), during the decades of socialism in Hungary, as a practicing lawyer, he could not professionally engage in legal ethnographic research, when he finally had the opportunity to do so in 1975 in the Ethnographic Research Group of the Hungarian Academy of Sciences, he presented a series of results of Hungarian legal ethnography. One of the most important of these was the publication of a monograph (Tárkány Szücs 1981), which is still considered to be the fundamental work of Hungarian legal ethnography, the conceptual and methodological foundation of the research field, the summary of research findings and at the same time its legitimation. Although the institutionalization of legal ethnographic research had not yet taken place at that time, Hungarian ethnography recognized Ernő Tárkány Szücs's research on legal folk customs as a “one-man” research field. During his research career, Tárkány Szücs continued to take an active role in international scientific life. He always considered it his task to make the findings of European legal ethnography known throughout Hungary, as well as to publish the findings of Hungarian legal ethnographic research in international scientific forums. The 2021 jubilee professional programs and publications of the Tárkány Szücs Ernő Legal Cultural Historical and Legal Ethnographical Research Group — an interdisciplinary research workshop established in 2011 with the aim of processing and enriching his research legacy and publications — were an opportunity to publish new research findings and formulate the ongoing tasks of Hungarian legal ethnography, beyond the evaluation of his research career and Hungarian legal ethnography from the dogmatic and methodological perspective.
Lablab purpureus: Evaluation and Selection of Drought-tolerant - High-yielding Accessions in Dry Farming Systems Based on Drought Tolerance Indices and Multi-environmental Yield Trials
Authors: MİSSANGA Julius , NDAKİDEMİ Patrick , VENKATARAMANA Pavithravani
Published: December 2022

Knowledge of plant responses to the soil moisture regimes is pre-requisite for drought tolerance studies. The present research study was performed to evaluate drought tolerant indices for selection of Lablab genotypes able to tolerate early Terminal Moisture Stress (TMS). The three evaluation sites from different agro-ecological conditions were selected for this study. Each of the site consisted of two trials with moisture stress-free (MSF) and early TMS conditions. The designs of the experiments comprised of a randomized complete block design. The twelve accessions used in the study were the best genotypes selected from the former moisture screening experiment at the seedling stage. Data collections included seed yield plant-1 at MSF and TMS conditions. The responses of Lablab accessions to TMS conditions were quantified through ten developed indices whose correlation coefficients (significant* @ p=0.05, ** @ p=0.01 at 5%) were computed from the mean of the seed yield plant-1 under both conditions. Based on this analysis, three indices; MP, GMP, and STI were discovered with higher correlation coefficients (> 0.5), and effective for selecting the TMS tolerant accessions with high seed yield plant-1 under both conditions. TMS tolerant accessions were selected based on combined rank mean method of desirable indices at all the sites. Through the combined rank mean method, D147, D363, HA4, D349, D352, D348, and D359 were generally selected as TMS tolerant accessions with high seed yield plant-1 across the sites. We therefore, suggest farmers' evaluation of the above-selected accessions in their fields before releasing them as commercial varieties.
Identification of Potential Indicators for Survival in Patients with Thyroid Cancer Based on Expression of FAM3 Members
Authors: Ma Yuting , Shi Junfeng , Liu Yongping , Cui Weiming , Pan Ruiyan , Qiu Hongyan , Han Fang , Hou Ningning , Sun Xiaodong
Published: December 2022

Thyroid cancer (THCA) is a common head and neck malignancy. The family with sequence similarity 3 (FAM3) is a cytokine-like gene family with four members, which is presumed to participate in the development of many cancer types. However, the expression patterns of FAM3s in THCA and their prognostic values, have not yet been established. We investigated differential expressions of FAM3 mRNA and protein in THCA, then validated the findings for FAM3B by immunohistochemistry. We also investigated survival data with respect to FAM3 expression patterns in patients with THCA. FAM3s information regarding their relationships with clinical pathological parameters were obtained and FAM3 mutations were assessed. KEGG and GO pathway regarding FAM3C were obtained using online databases. To investigate potential correlations between FAM3s and immune cell infiltration, we investigated the roles of FAM3s in immune cells of patients with THCA. The mRNA expression of FAM3C were significantly elevated in THCA tissues; high expression levels of FAM3C protein were also observed in THCA tissues. A significant association between the pathological stage and the expression of FAM3C was found in patients with THCA. Patients with THCA who had high mRNA expression levels of FAM3C exhibited significantly more favorable prognosis, compared with patients who had low mRNA expression levels of FAM3C. Overall, FAM3C may play vital roles in the pathogenesis and development of THCA, and these findings constitute novel insights for biomarkers of immunotherapeutic targeted agents and may aid in the identification of prognostic biomarkers for THCA.
SELF-ASSEMBLED SYNTHESIS OF MICROENCAPSULATED PARAFFIN WAX PHASE CHANGE MATERIALS WITH EXCELLENT THERMAL PROPERTIES OF CALCIUM CARBONATE SHELL
Authors: Liu Xinyi , Wang Jifen , Xie Huaqing , Guo Zhixiong
Published: December 2022

The PW@CaCO3 phase change microcapsule composites with paraffin wax (PW) as core and calcium carbonate (CaCO3) as shell were successfully prepared by the self-assembly method. During the preparation process, different core-to-wall ratios and different temperatures affected the morphology, encapsulation rate, thermal stability, and thermal conductivity of the microcapsules. Eight sets of microcapsule samples were prepared under different core-to-wall ratios and different temperatures. Of these microcapsule samples, it was found that the microcapsules performed the best thermal performance at a temperature of 65° C and a core-to-wall ratio of 1:1, with a melting enthalpy of 102.8 ± 1.7 J/g, a crystallization enthalpy of 103.9 ± 1.8 J/g, an encapsulation rate of 73.7 ± 1.5%, and a thermal conductivity of 1.251 ± 0.026 W/(m K). The results showed that the prepared microcapsules have good thermal storage properties and have good prospects for application in the field of energy storage buildings.
A special performance of magnetic nanocatalysts in biomedicine
Authors: Binandeh Mansour
Published: December 2022

Magnetic nanoparticles (MNPs) are the main source of synthesis and design of magnetic nanocatalysts, which are obtained from iron salts through the chemical coprecipitation method. The main goal of this research is to investigate the absorption, release and antibacterial properties of magnetic nanocatalysts with silica coating and silica/amine linkers. The structure of the obtained nanocatalyst can be detected through scanning electron microscopy, transmission electron miroscopy, energy-dispersive X-ray spectroscopy and infrared spectroscopy. There is a reaction between ampicillin (10 μl, 25 μg/ml) and Fe3O4@SiO2 and Fe3O4@SiO2/NH2 magnetic nanocatalysts (200 mg, 2 mol%) at 25°C and in double-distilled water. In this way, the amount of absorbed ampicillin on the MNPs@silica/amine structure in covalent form is higher than that on the MNPs@silica structure in non-covalent bonding form – namely, 85 to 65%. The rate of release in non-covalent form is above 90%, whereas in covalent form, it is less than 80%. Additionally, the bactericidal activity of nanocatalysts tested separately at a temperature of 37°C for the non-covalent type is 80% compared with that of the covalent type, which is 70%. The overall result was that the percentage efficiency of the absorption/release reaction in the non-covalent bonding state was 10% more than that for the non-covalent bonding state.
SAĞLIK SİSTEMİ BELİRLEYİCİLERİ VE GÖSTERGELERİ ÜZERİNE BİR YOL ANALİZİ ÇALIŞMASI
Authors: BÖRÜBAN Ceren , ÖZGÜR GÜLER Ebru
Published: December 2022

Bir ülkede yaşayan bireylerin yaşam kalitesini ve ülkenin beşerî sermayesini yakından etkilemesi nedeniyle sağlık hizmetlerinin kalitesinin, performansının ve etkinliğinin ölçülmesi önemlidir. Bu çalışmanın amacı, sağlık sistemi kalitesi belirleyicileri ve göstergeleri arasındaki nedensel ilişkileri 2018 itibariyle 135 düşük, düşük-orta ve üst-orta gelirli ülkeler için araştırmaktır. Sağlık sisteminin performansını yansıtan değişkenler sağlık göstergeleri, sağlık sisteminin kalitesini etkileyen değişkenler ise sağlık sistemi belirleyicileri olarak tanımlanmıştır. Belirleyiciler olarak; okuryazarlık oranı, kentsel nüfus (%) ve GSYH, sağlık sistemi göstergeleri olarak ise tüberküloz insidansı, beş yaş altı ölüm oranı ve cerrahi müdahale durumunda fakirleşme riski araştırma modelinde yer almıştır. İstatistiksel yöntem olarak gözlenen değişkenlerle yol analizi kullanılmıştır. Analiz sonucu; belirleyici değişkenlerin, önsel beklentilere uygun olarak tüberküloz insidansı dışındaki sağlık göstergelerini negatif etkilediği saptanmıştır. Sağlık sistemi belirleyicileri ve göstergeleri arasındaki nedensel ilişkilerin araştırıldığı az sayıdaki geçmiş çalışmalarda, gözlem birimlerinin belli bir ülke grubu (örneğin; sadece Batı Avrupa ülkeleri) veya aynı ülkenin belli bölgeleri ile kısıtlı olduğu görülmektedir. Farklı özellikteki ülkeleri kapsayan bir gözlem seti üzerinde, sağlık belirleyici ve göstergelerinin nedensel ilişkilerinin araştırılması bakımından çalışmanın özgün olduğu düşünülmektedir.
Accurate profiling of diazotrophic communities using unique molecular identifiers with Nanopore sequencing v1
Authors: Shigyo Nobuhiko
Published: December 2022

This protocol applies the method by Karst et al. (2021), who used UMI-tagged primers to perform highly accurate long-read amplicon analysis on the full-length ribosomal RNA operons, to the nitrogen fixation (nif) gene cluster. A recent study has shown that the functional gene nifH, which is frequently used in community analysis of diazotrophs, detects many false positives (Mise et al. 2021). Therefore, in this protocol, I used newly developed primers targeting the nifD-K gene (approx. 1.8 kbp) to identify the diazotrophic communities. The present protocol is presented using plant litter and mineral soil as examples, but it could potentially be applied in a variety of environmental samples.
Technologies for Analyzing and Calculating the Relationship between the Useful Component and the Noise of Noisy Signal in Monitoring Systems
Authors: Aliev T. A. , Musaeva N. F. , Quluyev Q. A. , Rzayeva N. E.
Published: December 2022

The article is devoted to the development of algorithms for calculating the cross-correlation function and the correlation coefficient between the useful signal and the noise of a noisy signal. The authors analyze the factors influencing the adequacy of the results of solving the problems of monitoring, control, management, etc. It is noted that when processing noisy signals, algorithms and technologies for separate processing of the useful component and the noise should be used. It is shown that in the event of malfunctions, such an important condition as the absence of correlation between the useful signal and the noise is violated in monitoring and control systems. Therefore, the problem arises of calculating the crosscorrelation function and the correlation coefficient between the useful signal and the total noise as well. Algorithms are proposed for calculating the estimates of the correlation coefficient and the correlation function between the useful signal and the noise of noisy signals. It is pointed out that the moment of occurrence of the correlation between the useful signal and the noise can be monitored in real time in information systems. It is shown that the estimate of the variance of the total noise before the appearance of the correlation is a stable value. When a correlation appears, the value of the variance of the total noise changes. The difference in the variance estimates is taken as an analogue of the estimate of the cross-correlation function between the useful signal and the noise at zero time shift.A technology for conducting computational experiments is proposed. Discrete values of the useful signal, noise and noisy signal are generated. The correlation coefficient and the cross-correlation function between the useful signal and the noise are calculated by the developed and traditional algorithms. A comparative analysis is carried out. It is shown that the proposed technologies for calculating the estimates of the cross-correlation function and the correlation coefficient between the useful signal and the noise, as well as the variance of the total noise, make it possible to extract additional important information from noisy signals. This opens up the opportunity to increase the efficiency of the analysis of noisy signals.
Quantifi cation of Changes in the Functional Status of a Person During the Aircraft Flight
Authors: Kruchinin P. A. , Kruchinina A. P. , Kudryashov I. A. , Liubkevich A. A. , Minyaylo Ya. Yu. , Podoprikhin M. A. , Chertopolokhov V. A.
Published: December 2022

The article is devoted to the approach to the quantitative estimation of changes in the functional state of a person during an airplane flight based on the results of stabilometric and oculographic examinations of airplane passengers carried out before and after the flight. Fourteen volunteers of both sexes participated in the study. They performed 21 pairs of pre-flight and post-flight examinations. For the existing sample of volunteers, parameters were identified that had a consistent trend of change. These parameters include visual tracking quality and stabilometric characteristics. In 70 % probes a decrease in the slow phases of optokinetic nystagmus average speed was noted. In most volunteers, changes in the stabilometric parameters for the optokinetic test and the balance test on an unstable support in the form of foam plate are noticeable. The tracking speeds, the average velocity of the pressure center, and the quality index of the equilibrium function decreased after the flight in more than 70 % of all samples. It was noted that the Hurst index after the flight decreased compared to background sample, during get up on the polyurethane foam plate in the vast majority of volunteers. In test before the flight the change in this parameter was multidirectional. In a stabilometric test with a "stepped deviation", in which a volunteer on command made quick bends at a small angle due to a change in the angle in the ankle joint, 75 % of the subjects after the flights showed a decrease in the average speed.
Comparative Analysis on Various CSS and JavaScript Frameworks
Authors: Khan Mohd Tauheed , Thompson Jordan , Carmine Amedeo , Reuter Grant
Published: December 2022

Web development is a huge part of the current world, affecting all parts of the world and human interaction. Learning about frameworks used in web development allows for increased development efficiency and increased website performance and functionality, based on knowing what technologies to apply when and where. This paper will examine various web framework technologies, specifically in the realm of CSS and JavaScript, and various frameworks that make use of them such as AJAX, Node JS, Bootstrap, and AngularJS, among others. This paper will provide analysis and explanation of these technologies’ designs, useful features, and potential shortcomings, and recommend which technology to use depending on various situations and web development environments.
Uzaktan algılama ile fay çizgiselliklerinin belirlenmesi: Baklan Grabeni örneği
Authors: KAYA Ali , AKYOL Erdal
Published: December 2022

Fayların belirlenmesi ve özelliklerinin ortaya konulması doğal afet risklerinin belirlenmesi, güvenli şehir altyapısı, büyük mühendislik yapılarının duraylılığı, yeraltı suları ile mineral zonlarının belirlenmesi açısından büyük önem taşımaktadır. Faylar yeryüzünde belirgin çizgisel yapılar oluştururlar ve bunlar genellikle yüzeyden kolayca ayırt edilebilirler. Fayların tespit edilmesi, haritalanması ve ilgili saha çalışmaları oldukça emek yoğun çalışma gerektirmektedir. Saha çalışmalarının yoğunluğunu azaltmak ve daha geniş alandaki yapısal bütünlüğü algılamak için hava fotoğrafları, yükseklik haritaları ve uydu görüntüleri kullanılmaktadır. Arazide sadece faylar değil, karayolu, demiryolu ve insan yapımı çit vb. karşıtlık oluşturan birçok farklı çizgisel yapı bulunmaktadır. Bu çizgiselliklerin tespiti ve analizinde uzaktan algılama görüntüleri yaygın olarak kullanılmaktadır. Bu çalışmada Landsat-7 (ETM+) uydu görüntülerinden yararlanılarak filtreleme, temel bileşenler analizi (TBA), bant oranlama, FCC (False Color Composite) bant kombinasyonları görüntüleme, sonuç çizgisellik haritası ve otomatik çizgisellik çıkarımı yöntemleriyle çizgisellik analizleri yapılmıştır. Elde edilen sonuçlar arazi çalışmalarından elde edilen verilerle karşılaştırılmıştır. Yöntemlerle genel çizgisellik hatları ortak olarak belirlenebilirken, belirlenen nesne sayısında farklılık olduğu, yönteme göre çizgiselliğe ait nesne sayısının değişebildiği ve en fazla nesne sayısının otomatik çizgisellik çıkarımı yöntemi ile üretildiği belirlenmiştir.
Optimal Spectrum Sensing Threshold for Unequal Priors Case
Authors: Javed Farrukh , Shafi Imran , Mahmood Asad
Published: December 2022

Classical spectrum sensing techniques utilize maximum likelihood (ML) detection for identification of spectrum holes. The approach is sub-optimal for the case of un-equal priors where the probabilities of channel occupation and vacancy are not the same. Such situations are bound to occur in most commercial bands such as GSM etc and hence are of more interest. The loss in performance has been disregarded as negligible in most of the work done on spectrum sensing techniques. This paper quantifies the effects of changing priors on classical energy detection and infers that the loss in spectrum sensing performance is not negligible. The deterioration is especially considerable at low SNR values and at low probabilities of channel occupation. An optimum threshold for achieving minimum probability of error has been derived in this work for unequal prior case. Detection based on the proposed threshold out-performs classical detectors under the assumption that priors are known at the receiver.
An Efficient Interference Aware Partially Overlapping Channel Assignment and Routing in Wireless Mesh Networks
Authors: V Sarasvathi , Iyengar N.Ch.S.N , Saha Snehanshu
Published: December 2022

In recent years, multi-channel multi-radio wireless mesh networks are considered a reliable and cost effective way for internet access in wide area. A major research challenge in this network is, selecting a least interference channel from the available channels, efficiently assigning a radio to the selected channel, and routing packets through the least interference path. Many algorithms and methods have been developed for channel assignment to maximize the network throughput using orthogonal channels. Recent research and test-bed experiments have proved that POC (Partially Overlapped Channels) based channel assignment allows significantly more flexibility in wireless spectrum sharing. In this paper, first we represent the channel assignment as a graph edge coloring problem using POC. The signal-to-noise plus interference ratio is measured to avoid interference from neighbouring transmissions, when a channel is assigned to the link. Second we propose a new routing metric called signal-to-noise plus interference ratio (SINR) value which measures interference in each link and routing algorithm works based on the interference information. The simulation results show that the channel assignment and interference aware routing algorithm, proposed in this paper, improves the network throughput and performance.
Predictive preemptive certificate transfer in Cluster-Based Certificate Chain
Authors: Boukli-Hacene Sofiane , Ouali Abdelkader , Bassou Asmaa
Published: December 2022

Mobile ad hoc networks are a set of nodes that cooperate and communicate wirelessly. This kind of networks in easy to deploy because there is no need of any pre-existing infrastructure. Security in Manets is a very important issue and it is hard to use conventional security techniques. Many approaches have been proposed to secure communication in Manets; most of them are based of public-key certifications which create a multitude of trust communication model.In this paper, we propose an amelioration of a distributed certificate chain that relies on the cluster based routing protocol. In our scheme, after forming clusters, the cluster-head node issue certificates for other nodes within its cluster. When a member node want migrates to an adjacent cluster, the cluster-head sends the node’s certificate to surrounding cluster-heads via gateway nodes. The protocol was doted by a preemptive predictive module to predict migration intention of member nodes. This approach has been evaluated by detailed simulation study. Simulation results show that this approach is scalable and generate lower certification overhead.
Securing Cluster Formation and Cluster Head Elections in Wireless Sensor Networks
Authors: Wang Gicheol , Cho Gihwan
Published: December 2022

In wireless sensor networks, clustering plays a very important role for energy savings at each node because it reduces the number of transmissions through TDMA based communication. For secure clustering, it is very crucial to find compromised nodes and remove them during the initial cluster formation process. If some nodes are compromised and survive from the exclusion process of normal nodes, they can make some nodes have a different membership view in the same cluster and consequently separate a cluster into multiple clusters. To resolve these problems, we propose a robust scheme against such attacks in this paper. First, our scheme generates large sized clusters to improve the quality of clusters. Second, our scheme exploits the verification of two hop distant nodes to maintain the quality of the large sized clusters and avoids the separation of the clusters. In addition, our scheme prefers broadcast transmissions to reduce the energy consumption of nodes. We prove that our scheme generates fewer clusters and is more secure and energy-efficient than its rival scheme through security analysis and simulation results. With regard to CH election, we also propose a scheme which securely elects CHs by recognizing the compromised nodes and depriving them of their CH candidacy. To this aim, each node in a cluster calculates reputation values of other CH candidates according to their behavior and distributes them through a broadcast. Then each node extracts substantial reputation values of CH candidates using the distributed reputation values. Next, each node evaluates the substantial reputation values of other CH candidates and excludes some disreputable nodes from CH candidates. The scheme greatly improves non-manipulability and agreement property of CH election results in comparison with other rival schemes. Moreover, the scheme guarantees higher non-manipulability and agreement property than other rival schemes, even in a loss-prone environment.