bluuebunny/crossref_metadata_2025 huggingface dataset:
Die DSH als hochschulische Prüfung – Merkmale und Qualitätssicherung
Authors: Appel Berit , Fazlić-Walter Ksenija , Overmann Hans , Cotelo Kristin Stezano , Wollert Mattheus
Published: July 2022

Bereits Ende der 90er-Jahre wurden die Vor- und Nachteile der DSH-Prüfung sowie die Möglichkeit ihrer Weiterentwicklung diskutiert und die Frage nach einer zentralen oder dezentralen Erstellung spielte eine große Rolle. Im Beitrag werden Begriffe, die für die DSH konstitutiv sind, diskutiert: sprachliche Studierfähigkeit, Studienbezug und Wissenschaftsorientierung.Des Weiteren wird herausgearbeitet, wie die in der RO-DT von 2011 eingeführte Qualitätssicherung aller Hochschulzugangsprüfungen das heutige Bild der DSH prägt und welche Rolle dabei der FaDaF einnimmt, der die DSH-Standorte bei der Vereinheitlichung von Qualitätsstandards unterstützt. Eine besondere Rolle spielen dabei Kriterienkataloge zur Erstellung und Begutachtung von Prüfungssätzen. Zudem werden die darauf basierende Beispiel-DSH und das DSH-Handbuch behandelt. Hervorgehoben werden in einem letzten Abschnitt außerdem die Neuerungen der DSH-Musterprüfungsordnung.Der Beitrag beleuchtet also, wie sich die DSH als dezentrale Prüfung im Wirkungsfeld zwischen DSH-Standorten, Hochschulen, HRK, FaDaF und der DSHGeschäftsstelle den Herausforderungen des 21. Jahrhunderts zu stellen versucht.
Impact of mental toughness on athlete’s performance and interventions to improve
Authors: Soundara Pandian P. Raja , Balaji Kumar Veera , Kannan Mahalingam , Gurusamy Gurubharathy , Lakshmi Biju
Published: July 2022

Mental toughness is the ability to handle pressure, adversity, and stress by overcoming failures. It is also the state of persisting without refusing to quit, with the possession of superiority in mental skills. This review aimed to describe the effect of mental toughness on the performance of athletes and also to have an insight into the various interventions to improve mental toughness. For this, PubMed was searched using the appropriate keywords till December 2021 and a narrative synthesis was performed. Mental tightness was evident to be correlated with many important aspects such as better performance, goal progress, withholding stress, coping, optimism and self-reflection. It also helps in a better level of confidence, constancy, control, positive cognition, visualization and challenges than the opponent team. Many interventional strategies have been adopted in previous years which mainly focused on personalized programs including psychological skills training, coping and optimism training, mindfulness, yoga, general relaxation, imagery, and a combination of both, and many more other aspects were observed to be effective in improving mental toughness. However, physical training alone did not observe to be beneficial. The current evidence indicates the important role of mental toughness on the sports performance of athletics and the role of various interventional strategies focusing on mindfulness and psychological interventions in improving mental toughness. All these interventional strategies need to be implemented in the actual practice.
Lu37Ru16.4In4– coloring and vacancy formation in a new structure type closely related to a 8 × 8 × 8bccsuperstructure
Authors: Gulay Nataliya L. , Kreiner Guido , Kalychak Yaroslav M. , Pöttgen Rainer
Published: July 2022

The lutetium-rich intermetallic compound Lu37Ru16.4In4was synthesized by induction melting of the elements in a sealed tantalum ampoule and subsequent annealing. The Lu37Ru16.4In4structure was refined from single crystal X-ray diffractometer data: new type,Ia3‾d$Ia\overline{3}d$,a = 2756.21(11) pm,wR2 = 0.0579, 3056F2values and 92 variables. The superstructure formation of Lu37Ru16.4In4is discussed on the basis of a group–subgroup scheme starting from thebccstructure as the aristotype.
The inclusion of students with disabilities and curricular adaptations in the educational units of the Jaramijó canton (Ecuador)
Authors:   Universidad Laica Eloy Alfaro de Manabí, Cedeño M. Esther , Párraga Ligia ,   Universidad Laica Eloy Alfaro de Manabí, Gómez Marjorie ,   Universidad Laica Eloy Alfaro de Manabí
Published: July 2022

This research addresses the importance of knowing how inclusion and curricular adaptations are applied in the educational units of the Jaramijó canton for students with disabilities, where the experiences of parents where illiteracy and overprotection prevent adequate development are considered as a sample. of the students, including a survey of teachers, where the lack of knowledge, lack of tools for the adequate development of educational inclusion was evidenced. A mixed methodology with a qualitative approach is proposed through life stories with semi-structured questions that allowed parents to express their feelings about the experiences they have had with their children with disabilities and the behavior they have adopted to overcome the different circumstances. of the events of his life, the quantitative method was also used through a structured survey of teachers, obtaining results that show how many are trained, need training and what tools they need to carry out inclusive educational work. According to the survey carried out on teachers, it indicates that, obtaining results that show how many are trained, need training and what tools they should carry out in inclusive educational work. According to the survey carried out on teachers, it indicates that, of 117 respondents, 75% of teachers make individual curricular adaptations, while 25% do not, arguing the importance of an inclusive approach to support educational processes that start from educational resources. in which the pertinent training can be carried out in order to be able to manage the existing resources and update knowledge by the pertinent organism such as the Ministry of Education.
Where are social policies? About State interventions and digitization processes in 4.0 societies
Authors:   Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Cena Rebeca
Published: July 2022

This paper analyzes the digitalization processes that involve social policies in their life cycle, from their inscription in what has been called 4.0 societies. The work is the product of e-interviews conducted with recipients of state interventions. It is concluded that: a) virtual environments constitute other spaces for the deployment of social policies that acquire relevant meanings and meanings for the study of their life cycle; b) the techniques involved in their study are part of a construction of the object of study that takes into account society 4.0 as the context of registration; and c) virtual environments are not devoid of interests, which, translated into algorithms, produce social stratification and distribute different capitals among users.
Duty of Loyalty to the State or the ‘Polish Section’ in the 1937 Estonian Constitution
Authors:   Tartu Ülikool (University of Tartu, Estonia), Siimets-Gross Hesi
Published: July 2022

There is a common comparison between the constitutions of the authoritarian regimes of Poland (1935) and Estonia (1937). The ideological model of the 1937 Estonian Constitution, especially in the section on loyalty to the state, was the 1935 Polish Constitution; for this reason, this section was also called the ‘Polish Section’. Compared to the first, 1920 Estonian Constitution, the 1937 Constitution was much more restrictive of basic rights, in particular through its general orientation and attitude. It was precisely in this that the so-called “loyalty to the state” section (§ 8) played a special role, affecting the whole chapter by its very nature, because it could, in its wording – and according to the example of Poland – constitute a general border clause on fundamental rights and freedoms. This article analyses specifically the ‘loyalty to the state’ section but first a short overview about historical background will be given. Secondly, the drafting of the section 8 of the Estonian Constitutions in the committees’ will be described and analysed, and thirdly, the discussions in the National Assembly will be summarized.
Raisons de la création et de l’évolution des formations frontalières polonaises dans l’entre-deux-guerres
Authors:   Uniwersytet w Białymstoku, Zawadzki Paweł
Published: July 2022

In establishing the thematic scope of this work, I assumed that its subject would be the process of the formation of border services in interwar Poland. This means a deliberate and complete disregard for the essentially distinct administrative role played by the border guard. The presentation of the Border Guard from an administrative perspective changes the situation so profoundly that a thorough discussion of its implications would certainly double the volume of the publication. A superficial treatment of the administrative issue would lead to misunderstandings. Furthermore, a superficial omission of the administrative issue was deemed necessary because the formations were mainly military in nature. Before going into details and elaborations, I would like to present my main research objective, which is the following question: what was the evolution of the legal status of Polish border formations in the inter-war period? In view of this objective, it is necessary to present the work from a historical perspective. The chronology of the facts is important for the subject matter, as it serves to systematise the considerations. The structure of the work and the research method were adjusted to the above-mentioned assumptions of the publication, which shows the reasons for the creation and the process of transformation of the border formations in relation to various types of institutional solutions, up to the moment of the creation of the Border Protection Corps and the Border Guard Corps, operating under these names until 1939. The potential conclusions resulting from this chapter concern: the presentation of the institutional construction of the border formations in the years 1918–1939 and the demonstration that in the interwar period they were the main organs of the Second Polish Republic, which guaranteed the inviolability of state territory and the security of the citizens on the subordinate territory.
Detection of BRAFV600E by digital PCR on fine-needle aspirate enables rapid initiation of dabrafenib and trametinib in unresectable anaplastic thyroid carcinoma
Authors: Buffet Camille , Allard Lucie , Guillerm Erell , Ghander Cécile , Mathy Elise , Lussey-Lepoutre Charlotte , Julien Nicolas , Touma Eliane , Quilhot Pauline , Godiris-Petit Gaelle , Lacorte Jean-Marc , Leenhardt Laurence , Denis Jérôme Alexandre
Published: July 2022

Introduction

Recently, targeted therapies using BRAFV600E and MEK inhibitors (dabrafenib and trametinib, respectively) have been recommended in BRAF-mutated anaplastic thyroid carcinoma (ATC). Considering the fast development of ATC, droplet digital PCR (ddPCR) performed on fine-needle aspirate (FNA), which is a rapid, reliable, and low-cost method, appears interesting for the detection of BRAFV600E mutation in these patients and allows early initiation of targeted therapies.

Results

In our two patients, both presenting extensive cervical masses inaccessible to surgery, ddPCR results were available in less than 24 h. Therefore, dabrafenib and trametinib were started only a few days after first contact.

Conclusions

We suggest that ddPCR on FNA be used in non-resectable cervical masses for rapid BRAFV600E mutation detection in the hope that starting targeted therapies early might improve outcomes.
Intrauterine malnutrition disrupts leptin and ghrelin milk hormones, programming rats
Authors: Parrela Jocemara Patrícia Silva de Souza , Borkenhagen Ingridys Regina , Salmeron Sarah Ramany Faria , Lima Thalyne Aparecida Leite , Miranda Ginislene Dias Souza , Costermani Hercules de Oliveira , Ricken Camila Luiza Rodrigues dos Santos , Alves Ester Vieira , Gomes Rodrigo Mello , de Oliveira Júlio Cezar
Published: July 2022

Herein, we assessed milk hormones, the biochemical composition of milk, and its association with neonatal body weight gain and metabolic homeostasis in weaned rats whose mothers were undernourished in the last third of pregnancy. From the 14th day of pregnancy until delivery, undernourished mothers had their food restricted by 50% (FR50), whereas control mothers were fed ad libitum. The litter size was adjusted to eight pups, and rats were weaned at 22 days old. Milk and blood from mothers, as well as blood and tissues from pups, were collected for further analyses. At birth, FR50 pups were smaller than control pups, and they exhibited hyperphagia and rapid catch-up growth during the suckling period. On day 12, the milk from FR50 mothers had higher energy content, glucose, total cholesterol, triglycerides, and acylated ghrelin but lower leptin and corticosterone levels. Interestingly, FR50 mothers were hypoglycemic and hyperleptinemic at the end of the nursing period. Weaned FR50 pups had an obese phenotype and exhibited insulin resistance, which was associated with hyperglycemia and hypertriglyceridemia; they also had high blood levels of total cholesterol, leptin, and acylated ghrelin. In addition, the protein expression of growth hormone secretagogue receptor (GHSR) in the hypothalamus was increased by almost 4-fold in FR50 pups. In summary, maternal calorie restriction during the last third of pregnancy disrupts energy and metabolic hormones in milk, induces pup hyperleptinemia and hyperghrelinemia, and upregulates their hypothalamic GHSR, thus suggesting that the hypothalamic neuroendocrine circuitry may be working to address the early onset of obesity.
Dependencia cultural, efecto demostración y la Economía Política de la Comunicación
Authors: Herrera Jaramillo Mauricio , Siqueira Bolaño César
Published: July 2022

Desde una perspectiva histórica, el presente trabajo pretende mostrar cómo durante la década de los 70, y bajo el enfoque de las teorías de la dependencia, la cultura toma protagonismo en el problema del desarrollo/subdesarrollo en América Latina. Valiéndonos del enfoque estructuralista de Celso Furtado –que describimos en la segunda parte del artículo- retomamos la noción denominada ‘efecto de demostración’, referenciada como estructural e inherente al problema del subdesarrollo a partir de la década de los 50. Para ello damos cuenta de las propuestas que desde los estudios críticos de la comunicación han realizado autores como Albertro Baltra, Edmundo Flores o Luis Ramiro Beltrán. Baltra y Flores abordan este tema desde la perspectiva del efecto de estallido social y de enraizamiento en la estructura social; análisis que difiere de la perspectiva vigente hasta ese momento que caracterizaba al subdesarrollo como inherente a problemas cognitivos o asociados a un pretendido atraso cultural de los países en América Latina. Por otra parte, este trabajo describe también la propuesta de la Economía Política de la Comunicación y la Cultura (EPC), que sustentada en un desarrollo teórico-metodológico propone que, al analizar las contradicciones del capital, es necesario adicionar a la tradicional contradicción capital-trabajo (subsunción del trabajo en el capital), el análisis de la contradicción economía-cultura (subsunción de la cultura popular en la economía), como punto de partida para superar las limitantes del ‘efecto de demostración’. Es así como es posible entender a la industria cultural como mediadora en los procesos que favorecen el fortalecimiento de la dependencia cultural en la periferia, y así comprender el significado real del concepto de ‘efecto de demostración’.
Empresas y cambio climático: internalización de los mecanismos de mercado en el sector privado brasileño (2005-2015)
Authors: Kiessling Christopher Kurt
Published: July 2022

This article addressed the process of building normative fit between the international and domestic arenas on climate change in Brazil, based on the study of the Brazilian private sector’s internalization and localization of market mechanisms. The questions that guided this article are: under what conditions did the internalization of the relaxation mechanisms of the Kyoto Protocol took place in the Brazilian domestic context? How has this internalization influenced the identities and interests of the business sector in Brazil and contributed to strengthening a domestic climate change governance arena? To achieve this objective, process tracing was used as the primary methodological tool from a constructivist approach to International Relations to understand the dynamics of interaction between the global and the national from the perspective of non-state actors.
Defense policy shaping foreign policy. An alternative interpretation through the study of the Argentine-Chilean Relations
Authors: Magnani Ezequiel , Barreto Maximiliano Luis
Published: July 2022

Which is the relationship between defense policy and foreign policy? How does defense policy influence foreign policy? The investigation is based on both questions. After a review of Argentinian literature analyzing the link between these policies, the article presents a new way of approaching the relationship between national defense and foreign policy based on the geopolitical concept of “axial point”. In this sense, the research suggests that, unlike traditional interpretations that place national defense as a secondary and complementary sphere to foreign policy, it is possible to argue that the former has a strong impact and influence on the latter. To empirically illustrate this new way of seeing the relationship between both policies, the article analyzes –using qualitative methodology linked to a single case study and based on the analysis of official documents and literature from that period– the bilateral relationship between Argentina and Chile, taking as central point of the analysis the Beagle Channel Conflict and considering the channel as an axial point. The paper concludes by showing how the case study illustrates the way in which defense policy impacts and influences foreign policy.
La elección de un candidato extremista: ¿anómalo o normal? La llegada de Donald Trump a la Casa Blanca en 2016
Authors: Álvarez del Castillo Calderón Carlos , Santa Cruz Arturo
Published: July 2022

Donald Trump’s 2016 successful electoral bid came as a surprise both to the public and pundits. Soon after the upset election, conventional wisdom settled on an explanation: that Trump’s victory was linked to Americans that felt left behind by globalization and the current political establishment. Conventional wisdom provided quick and straightforward answers. Nevertheless, these answers were incomplete. Chief among the missing elements of the improvised explanation was the radicalization of the Republican party. To fully understand how the transformation of the Republican Party resulted in President Trump’s election and his foreign  policy, this article will analyze the case through constructivist lenses. According to this perspective, identity plays a crucial role in both domestic and international politics. By providing an analysis of American identity and especially of the identity of the Republican Party, constructivism provides useful knowledge in the interpretation of both Trump’s election and his administration’s foreign policy. We argue that what really explains Trump victory in the electoral college in the November 2016 electoral process (he lost the popular vote by about three million votes) are ideational, identity-related factors—not his personality or the globalization-related arguments conventional wisdom focuses on.
L’egemonia globale del monoteismo: comprendere le Indie Occidentali attraverso l’Oriente
Authors: Catto Michela
Published: July 2022

L’obiettivo di questo lavoro è di attirare l’attenzione su alcuni testi della tradizione missionaria iberica in cui le Indie orientali e quelle occidentali sono messe in relazione e rese partecipi di un’unica grande storia dell’umanità. Lo stretto legame tra le due Indie, nella loro simbolica posizione a destra e a sinistra dell’Europa, è finalizzato certamente alla risoluzione degli enigmi relativi all’origine degli “indiani”, ma ha anche lo scopo di elaborare una teoria sulla diffusione del cristianesimo nel mondo. L’universalità della diffusione del messaggio evangelico sin dalle sue origini era provata attraverso le somiglianze e conformità che si riscontravano tra le Indie orientali e quelle occidentali. Esse facevano supporre migrazioni e contatti e suggerivano gradi di civiltà che appartenevano a fasi diverse di una medesima storia che i missionari erano chiamati a proseguire.
La ficticia corte en Europa misioneros y emperadores en la literatura anticristiana japonesa del siglo XVII
Authors: San Emeterio Cabañes Gonzalo
Published: July 2022

Aunque existe mucho trabajo desarrollado sobre la literatura anticristiana entre los siglos XVII y XIX en Japón, esta se ha centrado sobre todo, por un lado, en el estudio de los dogmas y principios utilizados para atacar el cristianismo y, por otro, en el estudio de las implicaciones socio-políticas del mismo. Este trabajo toma como referencia un viejo paradigma de la crítica anticristiana, la idea de que los misioneros y el cristianismo en sí formaban una quinta columna del expansionismo colonial ibérico, para ofrecer una representación de la manera en que los japoneses visualizaban en este periodo las sociedades y estructuras de gobierno de los países extranjeros, poniendo particular énfasis en la idea de emperador o monarca.
 
 
monarca.
Amplification of photoelectric injection in the photodiode based on large-grain cadmium telluride films
Authors:   Karakalpak State University named after Berdakh, Uzbekistan, 1, Abdirov str., 230012 Nukus, Republic of Karakalpakstan, Uteniyazov A.K. , Ismailov K.A. ,   Karakalpak State University named after Berdakh, Uzbekistan, 1, Abdirov str., 230012 Nukus, Republic of Karakalpakstan, Muratov A.S. ,   Karakalpak State University named after Berdakh, Uzbekistan, 1, Abdirov str., 230012 Nukus, Republic of Karakalpakstan, Dauletmuratov B.K. ,   Nukus State Pedagogical Institute named after Ajiniyaz P. Seyitov str., Nukus, Republic of Karakalpakstan, Kamalov A.B. ,   Nukus State Pedagogical Institute named after Ajiniyaz P. Seyitov str., Nukus, Republic of Karakalpakstan
Published: July 2022

The results of studies of photoelectric injection amplification in the Al–Al2O3–p-CdTe–Mo structure at high bias voltages for the forward current are presented. It has been shown that the spectral sensitivity reaches its maximum value Sλ = 8.4∙104 A/W, when the diode is illuminated with the “own” light at λ = 450 nm and V = 7 V, while when it is illuminated with the “impurity” light at λ = 950 nm Sλ = 4.3∙104 A/W under the same bias voltage. It has been established that when illuminating the structure with the “own” light, the positive feedback mechanism is realized, and when illuminating with “impurity” light, the parametric amplification mechanism is realized.
Field effects in electron-irradiated GaP LEDs
Authors:   National Pedagogical Dragomanov University, 9, Pyrohova str., 01601 Kyiv, Ukraine, Vernydub R.M. , Kyrylenko O.I. ,   National Pedagogical Dragomanov University, 9, Pyrohova str., 01601 Kyiv, Ukraine, Konoreva O.V. ,   E.O. Paton Electric Welding Institute, NAS of Ukraine, 11, Kazymyr Malevych str., 03150 Kyiv, Ukraine, Olikh Ya.M. ,   . Lashkaryov Institute of Semiconductor Physics, NAS of Ukraine, 41, prospect Nauky, 03680 Kyiv, Ukraine, Radkevych O.I. ,   SE “SRI of Microdevices” STC “Institute for Single Crystals”, NAS of Ukraine, 3, Severo-Syretska str., 04136 Kyiv, Ukraine, Stratilat D.P. ,   Institute for Nuclear Research, NAS of Ukraine, 47, prospect Nauky, 03680 Kyiv, Ukraine, Tartachnyk V.P. ,   Institute for Nuclear Research, NAS of Ukraine, 47, prospect Nauky, 03680 Kyiv, Ukraine
Published: July 2022

The paper presents the results of the study of field effects in non-irradiated and irradiated by electrons (E = 2 MeV, F = 8.2∙1016 cm–2) gallium phosphide (GaP) light emitting diodes (LEDs) under reverse bias. The avalanche multiplication of charge carriers and tunneling breakdown in the space charge region has been considered. An increase of breakdown voltage after electron irradiation has been revealed. The effects of the annealing of non-irradiated and irradiated diodes in the temperature range of 20 to 500 °C have been analyzed.
Nanophysics in modern medicine
Authors:   Institute of High Technology, Taras Shevchenko National University of Kyiv, Ukraine, Lozovski V.Z. ,   V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine, Lysenko V.S. ,   Institute of High Technology, Taras Shevchenko National University of Kyiv, Ukraine, Rusinchuk N.M. ,   Institute of High Technology, Taras Shevchenko National University of Kyiv, Ukraine
Published: July 2022

WNanophysics is rapidly developing for the recent couple of decades. Unique physical properties of materials at the nanoscale are the reason for this rapid development. Ideas, materials and structures of nanophysics have found their wide application in related fields of modern science, including biology and medicine. This short review is devoted to the application of nanophysics in modern medicine. The main focus was on application of ideas and physical phenomena of nanophysics in oncology and antiviral therapy. We have focused on the use of nanosystems both for tumor imaging and for the struggle against some types of tumors. The use of nanoparticles as nanocontainers for targeted drug delivery was briefly discussed. We also demonstrated how the effects of nanophysics can be used to develop new non-traditional methods of antiviral therapy. The focus of these methods was the idea of physical (field) action of nanoparticles on the viruses, which is based on the local-field enhancement effect that is the reason of ponderomotive forces acting on the viruses up to destruction of viral envelopes.
Intelligent electronic-optical sensor for information-measurement system of detection and identification of ground and aerodynamic objects
Authors:   Interdepartmental Scientific and Educational Physicotechnical Center of the Ministry of Education and Science and the National Academy of Sciences of Ukraine at the Odesa I.I. Mechnikov University, Lepikh Ya.I. , Santoniy V.I. ,   Interdepartmental Scientific and Educational Physicotechnical Center of the Ministry of Education and Science and the National Academy of Sciences of Ukraine at the Odesa I.I. Mechnikov University, Budiyanskaya L.M. ,   Interdepartmental Scientific and Educational Physicotechnical Center of the Ministry of Education and Science and the National Academy of Sciences of Ukraine at the Odesa I.I. Mechnikov University, Yanko V.I. ,   Interdepartmental Scientific and Educational Physicotechnical Center of the Ministry of Education and Science and the National Academy of Sciences of Ukraine at the Odesa I.I. Mechnikov University, Balaban A.P. ,   Interdepartmental Scientific and Educational Physicotechnical Center of the Ministry of Education and Science and the National Academy of Sciences of Ukraine at the Odesa I.I. Mechnikov University
Published: July 2022

This work describes an original intelligent electronic-optical (laser) sensor (EOS) operating in the infrared range for systems that detect ground and aerodynamic objects and send control commands to the executive devices of portable information-measurement systems using specified algorithms. EOS proposed here differs from the known analogues by its ability of early detection and recognition of high-speed special machinery objects and small-sized unmanned aircrafts. EOS generates and sends probing optical pulses in the direction of a monitored high-speed object, processes the reflected location signal and retrieves the object coordinates and motion parameters. The classification features of the object are determined from the parameters of optical location signal used for object identification with the account the specific nature of optical location information systems.
Зсувний модуль та структура хрящової тканини
Authors: Bulavin L.A. , Hnatiuk K.I. , Zabashta Yu.F. , Svechnikova O.S. , Tsymbaliuk V.I.
Published: July 2022

Хрящова тканина розглядається як полiмерний гель, сiтка якого утворена ланцюгами фiбрилярних бiлкiв та протеоглiканiв. Запропоновано модель такої сiтки, що складається iз сiтчастих блокiв, з’єднаних прохiдними ланцюгами. В рамках запропонованої моделi дослiджено механiзм деформацiї хрящової тканини. Розроблено механiзм деформацiї в рамках такої моделi. Отримано формулу для зсувного модуля у згаданiй моделi. Експериментально визначено величину зсувного модуля для еластичної хрящової тканини. Встановлено, що число прохiдних ланцюгiв у запропонованiй моделi для еластичного типу хрящової тканини становить 10.
Family Safety Reporting in Hospitalized Children With Medical Complexity
Authors: Mercer Alexandra N. , Mauskar Sangeeta , Baird Jennifer , Berry Jay , Chieco Deanna , Copp Katherine , Cox Elizabeth D. , Haskell Helen , Hennessy Karen , Kelly Michelle M. , Mallick Nandini , McGeachey Amanda , Melvin Patrice , Ngo Tiffany , Pinkham Amy , Rogers Jayne , Wickremasinghe Walter , Williams David , Landrigan Christopher P. , Khan Alisa
Published: July 2022

BACKGROUND AND OBJECTIVES

Hospitalized children with medical complexity (CMC) are at high risk of medical errors. Their families are an underutilized source of hospital safety data. We evaluated safety concerns from families of hospitalized CMC and patient/parent characteristics associated with family safety concerns.

METHODS

We conducted a 12-month prospective cohort study of English- and Spanish-speaking parents/staff of hospitalized CMC on 5 units caring for complex care patients at a tertiary care children’s hospital. Parents completed safety and experience surveys predischarge. Staff completed surveys during meetings and shifts. Mixed-effects logistic regression with random intercepts controlling for clustering and other patient/parent factors evaluated associations between family safety concerns and patient/parent characteristics.

RESULTS

A total of 155 parents and 214 staff completed surveys (>89% response rates). 43% (n = 66) had ≥1 hospital safety concerns, totaling 115 concerns (1–6 concerns each). On physician review, 69% of concerns were medical errors and 22% nonsafety-related quality issues. Most parents (68%) reported concerns to staff, particularly bedside nurses. Only 32% of parents recalled being told how to report safety concerns. Higher education (adjusted odds ratio 2.94, 95% confidence interval [1.21–7.14], P = .02) and longer length of stay (3.08 [1.29–7.38], P = .01) were associated with family safety concerns.

CONCLUSIONS

Although parents of CMC were infrequently advised about how to report safety concerns, they frequently identified medical errors during hospitalization. Hospitals should provide clear mechanisms for families, particularly of CMC and those from disadvantaged backgrounds, to share safety concerns. Actively engaging patients/families in reporting will allow hospitals to develop a more comprehensive, patient-centered view of safety.
Exposure to an accidental trichlorosilane spill: three case reports
Authors: Park Chang Won , Kim Seong Hun , Lee Soo Hyung , Kim Shinwoo , Nho Woo Young
Published: July 2022

Chlorosilane is a hazardous chemical compound which is used as a raw material in the production of silicone. Despite strict restrictions, accidental spillage of chlorosilane is often reported. However, human exposure was rarely reported in the past decades and the effect on humans is barely known. We report cases of human exposure to an accidental trichlorosilane spill. Three middle aged male industrial workers visited our emergency department after exposure to trichlorosilane. They presented with shortness of breath and burns on multiple sites. Chest radiograph and laboratory studies were performed. None of the reports showed serious results and were discharged after conservative management.
Estimación máxima verosimilitud de la probabilidad de ruina en el modelo de riesgo clásico con reclamaciones exponenciales
Authors: Pantí-Trejo Henry G. , Guerrero-Lara Ernesto A. , López-Flores Jesús E.
Published: July 2022

Se calculan los estimadores de máxima verosimilitud para los parámetros que definen al proceso de Poisson compuesto en el proceso de riesgo clásico con reclamaciones exponenciales. Se prueba consistencia y normalidad asintótica de los estimadores obtenidos. Finalmente, con ayuda de la propiedad de invarianza de los estimadores de máxima verosimilitud, la normalidad asintótica y el método delta, se realiza una estimación puntual y por intervalos de la probabilidad de ruina.
Control óptimo de orden fraccionario para un modelo de eficacia del tratamiento de la tuberculosis con presencia de VIH/Sida y diabetes
Authors: Delgado-Moya Erick , Pietrus Alain
Published: July 2022

En este trabajo, aprovechando las ventajas del uso de las derivadas de orden fraccionario en el sentido de Caputo, presentamos un estudio de control óptimo de la eficacia del tratamiento de la tuberculosis (TB) en presencia del VIH/SIDA y la diabetes. El modelo matemático que es controlado se encuentra en [17] y estudia la relación entre la tuberculosis, el VIH/SIDA y la diabetes con respecto a la eficacia del tratamiento y diferencia en tuberculosis multirresistente (TB-MDR), y tuberculosis extremadamente resistente (TB-XDR). La definición de los controles se centra en evitar la reinfección/reactivación, la TB-MDR y la TB-XDR en las diferentes subpoblaciones (TB únicamente, TB-VIH/SIDA y TB-Diabetes). El modelo dividido en subpoblaciones nos permite diferenciar los comportamientos de la transmisión y la resistencia y evaluar los diferentes costos en la aplicación de los controles. Realizamos simulaciones computacionales con datos de la literatura para estudiar nuestro problema de control en un escenario específico. Exploramos el comportamiento del número básico de reproducción variando la tasa de contacto efectivo y los parámetros asociados a la resistencia para diferentes valores de _ (orden fraccional). Estudiamos diferentes estrategias de control basadas en la activación de los controles y encontramos que la más efectiva es cuando activamos todos los controles. Con esta estrategia, reducimos el número de casos resistentes, principalmente en la TB-XDR en diabéticos que tiene un fuerte impacto en la dinámica de resistencia y transmisión de la tuberculosis. Además, esta estrategia evita el crecimiento futuro del número de casos resistentes.
Respondências: análises (online) em confinamento
Authors: Xavier Monalisa Pontes , Martins Ana Carolina B. Leão
Published: July 2022

Resumo Este artigo compreende oito cartas trocadas entre as autoras ao longo do mês de abril de 2020, tendo por eixo norteador o tema das análises online. Em uma retomada metodológica da produção teórica pela via das correspondências, amplamente utilizada entre Freud e seus interlocutores, propõe uma tessitura em ato de conceitos-acontecimentos em torno do atendimento mediado pelas tecnologias da informação e da comunicação, bem como dos deslocamentos no estatuto da escuta clínica, que reverberam especialmente sobre o inconsciente, a presença do analista e a questão do registro. A escrita epistolar possibilitou uma elaboração afetuosa e desinstitucionalizada, rompendo com a lógica academicista, sem perder o rigor conceitual do campo freudo-lacaniano na interlocução com outros autores. As discussões apresentadas refletem sobre quais vidas são passíveis de escuta nas análises, online ou não, em variados desdobramentos que circunscrevem uma clínica do contemporâneo.
Genetic diversity of Lippia origanoides Kunth. in natural populations using ISSR markers
Authors: Feijó Emily Verônica Rosa da Silva , Barbosa Bárbara Laís , van den Berg Cássio , Oliveira Lenaldo Muniz de
Published: July 2022

ABSTRACT Lippia origanoides Kunth. is a medicinal plant that is widely available in the Northeast region of Brazil and is known as “alecrim-d’angola”. However, there is no information available on the genetic variability of this species in the region. Thus, the current study was aimed to analyze the genetic diversity and structuring of L. origanoides populations occurring in the states of Bahia and Pernambuco, Brazil, using Inter-Simple Sequence Repeat (ISSR) molecular markers. The evaluated Nei’s diversity index of the populations varied from 0.162 to 0.237, and the Shannon diversity index varied from 0.247 to 0.350. In molecular variance (AMOVA) analysis, a variation of 31% was observed among the populations, which denotes a high interpopulation structuring. The structure analysis and dendrogram indicated the possibility of classifying the 18 populations into four groups. As their genetic structure is extremely high, it is important to collect L. origanoides germplasm, including as many populations as possible. Since the region of Chapada Diamantina holds the most diverse populations of L. origanoides germplasm, it is a priority area to obtain the germplasm.
Near infrared spectroscopy as a tool to discriminate tannins from Amazonian species
Authors: Nascimento Cristiano Souza do , Araújo Roberto Daniel de , Silva Claudia Eugênio da , Nascimento Claudete Catanhede do , Menezes Valdiek da Silva , Santos Joaquim dos
Published: July 2022

ABSTRACT Near infrared spectroscopy (NIR) is a tool capable of providing efficient results for organic molecules of different materials. We developed a predictive model using Fourier Transform NIR Spectroscopy to distinguish the types of tannins in different forest species in the Amazon. Samples were obtained from different regions of the State of Amazonas/Brazil, and tests for tannins were performed, including obtaining NIRS spectra. The assembly of spectral data matrices versus analytes of interest was crossed with the results of traditional analyses. In addition, a calibration and validation set was constructed for condensed tannins, hydrolyzable tannins, and samples with no tannins. Finally, the performance of classification models was evaluated for sensitivity, identification index, and errors. The condensed tannin classes were detected in 63% of the species studied, followed by 34% of the species not containing tannin. The discriminant analysis produced groupings of classes, with a hit sensitivity index >90%. The developed model can be applied in studies of ecology, forestry and chemotaxonomy, with a focus on phenolic compounds such as tannins. The proposed methodology has advantages over the reference methods, reflected as a lower need for sample preparation, shorter analysis time, no use of reagents, and, consequently, no generation of waste.
COMPARISON OF CHANGES IN THE ANKLE AFTER UNICONDYLAR KNEE ARTHROPLASTY AND HIGH TIBIAL OSTEOTOMY
Authors: Sari Abdulkadir , Dincel Yasar Mahsut , Cetin Mehmet Umit , Kilinc Seyran , Gunaydin Burak , Ozdemir Mikail
Published: July 2022

ABSTRACT Objectives: We aimed to compare the changes in the coronal alignment of the ankle joints and their clinical effects after high tibial osteotomy (HTO) and unicondylar knee arthroplasty (UKA). Methods: 50 HTO and 54 UKA patients who were operated on for medial knee osteoarthritis between 2013 and 2018 were retrospectively evaluated. The hip-knee-ankle angle (HKA), the medial proximal tibial angle (MPTA), the tibial plafond inclination (TPI) and the talar inclination (TI) angles were measured before and after operation. Visual analog scale (VAS), short form 36 (SF-36), and ankle-hindfoot scale (AHS) scores of both groups were evaluated and recorded. Results: Angular changes in the HKA, MPTA, TPI and TI values showed significantly greater values in the HTO group (p<0.001). When asymptomatic and symptomatic cases were compared, it was found that changes in the HKA, TPI and TI values were significantly greater in symptomatic cases in the HTO group (p<0.05). A significant decline was observed in the VAS, SF-36 and AHS scores in the HTO group in the postoperative period (p<0.05). In intergroup evaluations, a significant decline was detected in pain and functional scores of the HTO group when compared to the UKA group (p<0.05). Conclusion: Unicondylar knee arthroplasty can be a good alternative to HTO in selected cases for postoperative ankle complaints. Level of Evidence III; Therapeutic Studies Investigating the Results of Treatment.
HOW USEFUL IS ELASTOGRAPHY IN THE FOLLOW-UP OF ACHILLES TENDON REPAIR?
Authors: Çetin Mehmet ümit , Sökmen Bedriye Koyuncu , Fidan Fırat , Mutlu Harun , Sari Abdülkadir , Dinçel Yaşar Mahsut , Kazdal Cengiz
Published: July 2022

ABSTRACT Introduction: In addition to conservative modalities in the treatment of Achilles tendon injuries, open, percutaneous and minimally invasive semi-open techniques, as well as biological open surgical repair methods are used as surgical options. Compression elastography is one of the methods used for the follow-up of treatment in Achilles tendon injuries. Methods: 23 patients were included in our study between July 2013 and June 2014, as long as they had at least 4 years of follow-up. In the final control, the intact side and the operated side were both examined and compared. The variables were the American Orthopedic Foot and Ankle Score (AOFAS) which is measured as a functional score considering plantar flexion and dorsiflexion; calf circumference; Achilles tendon anteroposterior (AP) diameter; and elastographic examination. Results: The strain ratio value and AP diameter of the patients was significantly higher on the operated side than on the non-operated side (p <0.001). There was no significant difference between the plantar flexion and dorsiflexion degrees on the operated side of the patients(p> 0.05). No correlation was observed between strain ratio and AOFAS (p: 0,995). Conclusion: Elastography is not a useful technique to evaluate functional results on long-term tendon healing. Level of Evidence III; Retrospective comparative study.
IS VOLAR PLATING IN DISTAL RADIUS FRACTURES SAFE REGARDING PRONATOR QUADRATUS?
Authors: Turgut Necmettin , Akgül Turgut , Biçen Fuat , Şahinkaya Türker , Kendirci Alper Şükrü , Ayık Ömer , Şen Cengiz
Published: July 2022

ABSTRACT Objective: This study aimed to investigate whether isokinetic strength decrease significantly after using volar plating for distal radius fractures and evaluate the pronator quadratus muscle regarding atrophy. Methods: This study took place between 2011 and 2015 and included 18 distal radius fracture patients (group 1) who were treated via volar plating at least one year prior and 14 healthy controls (group 2). All participants were tested isokinetically. Grip strength, radiological evaluation, wrist range of motion, disabilities of the arm, shoulder, and hand and visual analog scale scores were assessed for clinical and functional outcomes. Ultrasonography evaluated the pronator quadratus muscle thicknesses. Results: The peak supination torque (PT) and supination work per repetition (WPT) strength values significantly decreased (p:0.039, p:0.025, respectively). Although we determined an 11% pronation PT deficit and a 19% pronation WPT deficit, neither were significant. In group 1, the pronator quadratus muscle thickness decreased 5.9% ± 13.3 in the radial area and 9.7% ± 10.5 in the interosseous area according with ultrasonography; these results were not statistically significant compared to group 2. All clinical and functional outcomes were not statistically significant between the groups. Conclusion: The use of volar plating after distal radius fractures is a safe method regarding isokinetic strength and pronator quadratus muscle atrophy. Level of evidence III; Retrospective case-control study .
NO SIGNIFICANT EFFECT OF 3D MODELLING ON SURGICAL PLANNING IN SPINAL DEFORMITIES
Authors: Guran Ortac , Oflaz Hakan , Gunal İzge
Published: July 2022

ABSTRACT Objective: To evaluate the effect of 3d printed models on surgical pre-operative planning of complex spinal deformities. Methods: In our study, five orthopedic surgeons made surgical planning of 5 patients with severe spinal deformity in three conditions: X-ray with computer tomography (X-ray-CT), 3D-computed tomography (3dCT), and 3d printed spine models. Operation plans were examined according to the level and number of instrumentations, osteotomy level, and time required for decision-making. Results: X-ray-CT, 3dCT, and 3d modeling methods were compared, and no statistically significant difference was observed in the number of screws and osteotomy score to be used in operation. The time required for decision ranking is 3d Model, 3d CT, and Xray-CT. Conclusions: 3d printed models do not influence the operative plan significantly; however, it reduces surgical planning time at pre-op duration, and those models gave some opportunities to practice with implants on a patient’s 3d spine model. Level of Evidence III; Diagnostic Studies - Investigating a Diagnostic Test .
Ethanol lock prophylaxis in long-stay central venous catheters in children with severe intestinal dysfunction: a report of six cases
Authors: Falcão Mário Cícero , Castro Gabriela Ibrahim Martins de , Framil Juliana Valeria de Souza , Bigio Juliana Zoboli Del , Tannuri Ana Cristina Aoun
Published: July 2022

Abstract The aim of this study was to report on use of ethanol lock in long-term catheters in newborns with severe intestinal dysfunction, dependent on total and prolonged parenteral nutrition, in a Neonatal Intensive Care Center (tertiary level), between 2015 and 2020. Six infants (0.65%) out of the 914 admitted during the period met the inclusion criteria. The median age at catheter placement was 121.5 days. Two Powerpicc (PICC Power Sinergy™, São Paulo), one Groshong (Groshong™ Central Venous Catheter BD, São Paulo), and three silicone catheters were used, all tunneled, and the median dwell duration was 182.5 days. Four patients had at least one episode of infection related to the central venous catheter, and Gram-positive, Gram-negative, and fungal agents were isolated. The median length of hospital stay was 555 days and mortality was 33.3%. The ethanol lock did not cause any side effects and was relatively effective in preventing infections related to the central venous catheter.
Human resources policies, learning, and turnover intention in organizations
Authors: Freitas Alessandra Demite G. , Lacerda Fabricio M. , Santos Enise A. , Alvarenga Marcelo A. , Bizarrias Flávio S.
Published: July 2022

Abstract Purpose: The objective of this research is to investigate how human resources policies and the perception of learning opportunities in organizations influence the intention of professional turnover. Originality/value: The authors demonstrated that, by understanding the existing relationships between the researched constructs, organizations should increase their investments in improvements in human resources policies, particularly in actions that promote a greater perception of learning opportunities, which reduce the intention of employee turnover of their talents. Design/methodology/approach: This research was developed with a quantitative approach and data collection was carried out through a survey. The questionnaires were applied to 250 professionals working in the labor market and students from a private university. Data analysis was performed with a confirmatory factor analysis and, subsequently, a structural equation modeling. Findings: The authors presented the research results in a descriptive way, the three hypotheses defined for the study were accepted, and the dimensions of human resources policies were considered significant. The authors presented relevant attributes for the understanding that, even though there are several reasons that can influence a professional in his decision to leave the organization, new factors must be considered, such as the possibilities of a greater offer of knowledge.