bluuebunny/crossref_metadata_2025 huggingface dataset:
Broadband transparent and flexible silver mesh for efficient electromagnetic interference shielding and high-quality free-space optical communication
Authors: Lei Qiyun , Luo Zhonglin , Zheng Xinyi , Lu Na , Zhang Yiming , Huang Jianfeng , Yang Liu , Gao Shiming , Liang Yiyong , He Sailing
Published: December 2022

A broadband transparent and flexible silver (Ag) mesh is presented experimentally for the first time for both efficient electromagnetic interference (EMI) shielding in the X band and high-quality free-space optical (FSO) communication. High transmission is achieved in a broad wavelength range of 0.4-2.0 µm. The transmittance of the Ag mesh relative to the substrate is around 92% and the sheet resistance is as low as 7.12 Ω/sq. The Ag mesh/polyethylene (PE) achieves a high average EMI shielding effectiveness (SE) of 28.8 dB in the X band with an overall transmittance of 80.9% at 550 nm. High-quality FSO communication with small power penalty is attributed to the high optical transmittance and the low haze at 1550 nm, superior to those of the Ag NW networks. With a polydimethylsiloxane (PDMS) coating, the average EMI SE is still up to 26.2 dB and the overall transmittance is increased to 84.5% at 550 nm due to antireflection. The FSO communication does not change much due to the nearly unchanged optical property at 1550 nm. Both the EMI shielding performance and the FSO communication function maintain after 2-hour chemical corrosions as well as after 1000 bending cycles and twisting. Our PDMS/Ag mesh/PE sandwiched film can be self-cleaned, suitable for outdoor applications.
Eyes on me: Investigating the role and influence of eye-tracking data on user modeling in virtual reality
Authors: Jeong Dayoung , Jeong Mingon , Yang Ungyeon , Han Kyungsik
Published: December 2022

Research has shown that sensor data generated by a user during a VR experience is closely related to the user’s behavior or state, meaning that the VR user can be quantitatively understood and modeled. Eye-tracking as a sensor signal has been studied in prior research, but its usefulness in a VR context has been less examined, and most extant studies have dealt with eye-tracking within a single environment. Our goal is to expand the understanding of the relationship between eye-tracking data and user modeling in VR. In this paper, we examined the role and influence of eye-tracking data in predicting a level of cybersickness and types of locomotion. We developed and applied the same structure of a deep learning model to the multi-sensory data collected from two different studies (cybersickness and locomotion) with a total of 50 participants. The experiment results highlight not only a high applicability of our model to sensor data in a VR context, but also a significant relevance of eye-tracking data as a potential supplement to improving the model’s performance and the importance of eye-tracking data in learning processes overall. We conclude by discussing the relevance of these results to potential future studies on this topic.
Biomass Carbon and Nitrogen allocation in different tree species: do tree compartments and size affect C:N relationship?
Authors: Sione Silvana , Ledesma Silvia , Aceñolaza Pablo , Wilson Marcelo
Published: December 2022

Tree carbon (C) and nitrogen (N) concentrations and C:N ratio are critical for understanding the elemental compositions of forests, N use efficiency, productivity and the biogeochemical cycles. We evaluate differences in C and N allocation among biomass compartments of three N‑fixing tree species of Espinal Argentine eco-region; the scaling relationship between C and N and the C:N ratio variation among compartments and tree size. Neltuma affinis (Spreng.) C.E. Hughes & G.P. Lewis, Neltuma nigra (Griseb.) C.E. Hughes & G.P. Lewis and Vachellia caven (Molina) Seigler & Ebinger plants (n = 30 for each species) were felled, grouped by stem basal diameter-based size classes and partitioned into 3 biomass compartments: stem (st), large branches (lb) and small branches + leaves, flowers and fruits (sbl). C and N concentrations were markedly influenced by species and biomass compartments. In general, sbl compartment presented more N than the st and lb, while C concentrations in Neltuma stems were the highest. Overall, no isometric C–N scaling relationships were found in different compartments. C:N variations in compartments were positively correlated with N concentrations but did not exhibit any significant association with C concentrations. C:N ratios differed significantly among species and biomass compartments. The C:N ratio for compartments ranked in an order of st > lb > sbl. C:N ratio variability in sbl was the least. Only in N. affinis and V. caven stems C:N relationship differed among tree size. Our results provide evidence of the importance of using in situ C and N concentration per main tree species and biomass compartments, to more accurate estimates of C and N stocks.
PREPARATION AND PHYSICO-CHEMICAL CHARACTERISTICS OF THE WATER-SOLUBLE COMPLEX OF THE GOSSYPOL DERIVATIVE
Authors: Rezhepov Kuralbay Zhadigerovich , Ziyaev Khairulla Lutfullaevich , Alimbayeva Shiirin Bekniyaz kizi
Published: December 2022

The article is devoted to the study of the process of obtaining a new water-soluble complex of the imino derivative of gossypol, its physicochemical and structural parameters. N-polyvinylpyrrolidone (N-PVP, M.m. 8000) for medical use was chosen to obtain the complex of the imino derivative of gossypol. During the study, we tested the methods for obtaining several complexes, which are proposed in the classical literature and information resources. The following method was used to obtain the complex: the imino derivative of gossypol was mixed with the polymer at room temperature for 24 hours in a solvent system (acetone : water 3 : 1). Thus, a water-soluble complex of gossypol with N-PVP was obtained, which was purified and dried. The yield of the final product was 75.35%.

To study the spectral properties of the obtained substances, modern UV and IR spectroscopy instruments were used. The results were analyzed and compared with data presented in the scientific literature. The proposed structure of the resulting water-soluble supramolecular complex is proposed.
CHEMICAL COMPOSITION AND MECHANICAL PROPERTIES OF VARIOUS PARTS OF BIRCH WOOD
Authors: Vedernikov Dmitriy Nikolaevich , Leontyev Leonid Leonidovich , Morskoy-Lemeshko Pavel Dmitrievich , Eltsova Liubov Sergeevna
Published: December 2022

The article compares mechanical parameters, group chemical compositions, iron content, lipid compositions before and after saponification, moisture, bulk density in three parts of Betula pubescens Ehrh. birch wooden parts: sapwood, false heartwood, false heartwood border. The strength properties of the false heartwood are worse than those of sapwood. The border of the false core is sometimes stronger than that of other parts. Evaluation is carried out in terms of hardness, flexural strength and compression strength. False heartwood, and even more so its border, contain more extractives extracted by ethanol, water, alkali solution, methylene chloride and less iron. The content of other components: cellulose, lignin, other polysaccharides differs, but less significantly. False heartwood border is heavier than the other wooden parts. Moisture content of the various parts decreases in the following order: false heartwood border, false heartwood, sapwood. The composition of the extractives extracted by methylene chloride is different in different parts. The composition is determined by gas-liquid chromatography-mass spectrometry before and after saponification of esters. Differences in sterols are given. An increased content of monoterpene alcohols and arylheptanoids is observed at the border. Differences in the properties of different wooden parts of a tree are explained by different amount and composition of extractives.
COMPONENT COMPOSITION OF ESSENTIAL OIL AND ANTIOXIDANT ACTIVITY OF POTAMOGETON PERFO-LIATUS L. (POTAMOGETONACEAE) GROWING IN THE ASTRAKHAN REGION
Authors: Krylova Yuliya Viktorovna , Novichenko Ol'ga Viktorovna , Kurashov Yevgeniy Aleksandrovich
Published: December 2022

For the first time, the component composition of the low-molecular-weight metabolome of perfoliate pondweed (Potamogeton perfoliatus L., family Potamogetonaceae), which grows in the Astrakhan region (lower zone of the Volga river delta), has been investigated. Low molecular weight organic compounds (LMWOCs) in the composition of essential oil were obtained from dried plants by steam hydrodistillation using the Clevenger apparatus. The qualitative and quantitative compositions of the LMWOCs were investigated using gas chromatography-mass spectrometry (GC/MS complex TRACE ISQ (Thermo Scientific) with a quadrupole mass analyzer). The low molecular weight metabolome of P. perfoliatus contained 164 components, of which 151 were identified. Major LMWOCs were carboxylic acids – tetradecanoic (69.7%) and hexadecanoic (10.1%), as well as phytol (3.4%) and phyton (1.4%), characterized by diverse biological activities. The antioxidant activity of an aqueous-alcoholic extract of P. perfoliatus was investigated by a photometric method based on the reaction of DPPH (2,2-diphenyl-1-picrylhydrazyl) dissolved in ethanol with an antioxidant sample. It has been shown that P. perfoliatus extract has more pronounced antioxidant properties than the tested drugs (ascorbic acid and emoxipine). P. perfoliatus from the lower zone of the Volga River delta can be considered as a naturally renewable resource for obtaining raw materials for creating effective composites of new generation algicides to combat cyanobacterial "bloom", as well as for obtaining valuable natural forms of LMWOCs of plant origin for various types of application in pharmacology, medicine, cosmetology, food industry, and other industries.
HEAVY METALS AND FATTY ACID COMPOSITION OF RANUNCULUS CIRCINATUM (SIBTH.) SPACH. (RA-NUNCULACEAE) FROM THE DELTA OF THE SELENGA RIVER
Authors: Zhigzhitzhapova Svetlana Vasil'yevna , Dylenova Elena Petrovna , Nikitina Elena Petrovna , Shiretorova Valentina Germanovna , Abaturov Artem Nikolaevich , Anenkhonov Oleg Arnoldovich , Bazarsadueva Selmeg Vladimirovna , Radnaeva Larisa Dorzhievna
Published: December 2022

Ranunculus circinatus Sibth. is a boreal, Eurasian species. The content of heavy metals and the composition of fatty acids in R. circinatum from the Delta of the Selenga River, which is the main tributary of Lake Baikal, was studied for the first time in this paper. Plants of R. circinatum of the Selenga river delta accumulated heavy metals in significant quantities, mostly Fe and Mn, and the content of Pb and Cd was below detection limit. Palmitic C16:0, myristic C14:0 and stearic C18:0 acids were the main saturated fatty acids. The content of unsaturated acids ranged from 53.67 to 58.60%, and they were represented by acids of n3-, n6-, n7- and n9-families. Unsaturated linolenic 18:3 ω3, linoleic 18:2 ω6 and palmitoleic 16:1n7 acids were dominant regardless of the place and year of sampling. The presence of iso-, anteiso- and 2-hydroxy acids was associated with the growth of microbial communities on plants, when the presence of 17:1 n7 and 20:3 n6 acids were associated with animals in vegetation bed of B. circinatum. The obtained data confirmed that plants contribute to the operation of such a powerful natural biofilter as the delta of the Selenga River.
CONTENT OF BIOLOGICALLY ACTIVE SUBSTANCES IN THE ABOVEGROUND PART OF SOME STONECROPS (SEDOIDEAE)
Authors: Fomina Tat'yana Ivanovna , Kukushkina Tat'yana Abdulkhailovna
Published: December 2022

The results of a comparative study of the content of biologically active substances in 8 species of the Sedoideae subfamily Aizopsis aizoon (L.) Grulich, A. hybrida (L.) Grulich, A. kurilensis (Vorosch.) S. Gontch., Hylotelephium ewersii (Ledeb.) H. Ohba, Sedum album L., S. hispanicum L., S. rupestre L., S. spurium M. Bieb. are presented: The aboveground shoots collected during the mass flowering phase were analyzed. The dry matter content was determined by drying of raw materials at 100‒105 °C. The amount of phenolic compounds, pectin substances, and total sugars was determined spectrophotometrically using SF-56 (Russia) and Agilent 8453 UV-Vis (USA) devices; the concentration of ascorbic acid was determined by titrimetric method. It was established the content of dry substances (up to 18.94%), flavonols (up to 4.45%), catechins (up to 3.72%), tannins (up to 20.2%), pectins (up to 13.36%), and sugars (up to 39.54%) per mass of absolutely dry raw materials, and ascorbic acid – up to 123.7 mg% per raw mass. A. kurilensis has the greatest capacity to accumulate bioactive substances. The data point to the prospects of stonecrops as a potential source for the production of food and feed additives.
GROWTH PROMOTING ACTIVITY OF FLAVONOIDS OF EXTRACTS OF POPULUS POPULUS BALSAMIFERA BUDS
Authors: Meshchanova Anna Gennad'yevna , Byzova Yuliya Sergeyevna , Ostrovnoy Kirill Aleksandrovich , Polyakov Vladilen Vasil'yevich
Published: December 2022

At present, the urgent task is to accelerate the development of alternative measures for the protection of plants, which is associated with the aggravation of the environmental situation, the desire to reduce pollution of agricultural landscapes and obtain agricultural products with minimal use of agrochemicals. Poplar extract is a plant growth stimulant due to the presence in its composition of saturated and unsaturated fatty acids, lipids, phenolic and polyphenolic compounds, amino acids, essential oils, vitamins, which provide a stable growth-stimulating effect.The aim was to evaluate the stimulating activity of extracts of balsamic poplar buds Populus balsamifera on the seed productivity of flax.

Tasks: isolate the amount of flavonoids from balsamic poplar; to establish the growth-stimulating activity of balsamic poplar bud extract in relation to flax seeds.

Methodology and scientific approaches: The method for obtaining the proposed balsam poplar extract includes the use of balsam poplar buds, air drying, grinding, extraction with 90% ethanol in a Soxhlet apparatus, filtration and evaporation to obtain the target product.

Results and conclusions: the results of studying the growth-stimulating activity of extracts of balsam poplar Populus balsamifera showed high seed productivity of flax of Tomsk selection in the control group; reproduction conditions had a positive effect on the yield of flax.
COMPOSITION OF LIPOPHILIC COMPONENTS OF RHODODENDRON ADAMSAY ETHER EXTRACT AND AC-TIVITY AGAINST SARS-COV-2 MAIN PROTEASE
Authors: Kukina Tat'yana Petrovna , Yelshin Ivan Aleksandrovich , Sal'nikova Ol'ga Iosifovna , Kolosov Petr Vladimirovich , Sandag Tsogtsaykhan , Karakay Dar'ya Aleksandrovna , Bondareva Mariya Aleksandrovna , Nefedov Andrey Alekseyevich , Chirkova Varvara Yur'yevna , Sharlayeva Yelena Anatol'yevna , Belen'kaya Svetlana Valer'yevna , Shcherbakov Dmitriy Nikolayevich
Published: December 2022

The composition of the lipophilic components of the Adams rhododendron RhododendronadamsiiRehd. Acid and neutral components were identified using gas-liquid chromatography with mass spectrometric detection. Methyl tert-butyl ether (MTBE), which has all the advantages of diethyl ether, but is devoid of its disadvantages, was used as the raw material extractant. It does not form peroxides and does not create increased gas contamination due to its higher boiling point. As a result, comparison with databases identified triterpene, phenolcarboxylic and aliphatic acids with a chain length of 8 to 30 carbon atoms, including saturated, unsaturated and dibasic acids. More than 150 triterpene and aliphatic components of the unsaponifiable residue and acid fractions have been identified. Previously, unsaponifiable residues of lipophilic extracts were practically not studied. Only components of Rh.adamsiiand other species of the genus rhododendron essential oils have been studied in detail. For bioactivity testing, samples of the whole extract and its fractionation products were prepared. Some of the studied samples show inhibitory activity against the main protease of SARS-CoV-2.
ISOLATION OF DIHYDROQUERCETIN AND ARABINOGALACTAN FROM LARCH WOOD WITH WATER-ETHANOL SOLUTIONS
Authors: Levdansky Vladimir Aleksandrovich , Levdansky Aleksandr Vladimirovich , Kuznetsov Boris Nikolayevich
Published: December 2022

Siberian larch wood (Larix sibirica Lebed.) contains such valuable biologically active substances as dihydroquercetin (DHQ) and arabinogalactan (AG), promising for the use in the pharmaceutical and food industries. An urgent task is to improve the methods of extraction isolation of these compounds from wood. In this work, we studied the possibility of simultaneous isolation of dihydroquercetin and arabinogalactan by extraction of larch wood with 5–25% aqueous ethanol solutions. It has been shown that by extracting wood with aqueous solutions with a low concentration of ethanol, it is possible to exclude the stage of separation of resinous substances from the target products of DHQ and AG. By experimentally optimizing of water-ethanol extraction process, it was shown that the highest yields of DHQ (1.8% mas.) and AG (18.0% mas.) were achieved by extraction of larch wood, crushed to particles of 1–3 mm in size, with a 15% ethanol solution for 2 hours. That the preliminarily mechanical treatment of larch wood allows to reduce the time of water-alcohol extraction to 30 minutes and to obtain DHQ and AG with high yields. The structure of DHQ and AG was confirmed by FTIR and NMR spectroscopy. Identification and purity of DHQ isolated from larch wood were confirmed by a photometric method using the reaction of cyanidin chloride formation when DHQ in heated in ethanol in the presence of hydrochloric acid.
Mapeamento do descarte de resíduos de construção e demolição no bairro Alto Bom Jesus
Authors: Melo Éverton César Nere , Vieira Glauber Islan Ferreira , Nascimento Elivelthon Carlos , Marinho Rafaella Pereira , Barros Vitor Hugo de Oliveira , Oliveira Miguel Vicente Canafistula de
Published: December 2022

O processo de ocupação urbana, quando não fiscalizado, promove a persistência de diversos problemas urbanos. A geração de resíduos de construção e demolição é uma dessas consequências, fator esse que, se não supervisionado, favorece o descarte irregular dos rejeitos. Por falta de infraestrutura urbana, esses resíduos são descartados em locais inadequados, sendo esses, áreas verdes, margens fluviais e terrenos baldios. Afetando o meio ambiente e a qualidade de vida da população local. O presente artigo visa identificar, classificar e mapear esses pontos de descarte irregular dos resíduos de construção e demolição presentes no bairro Alto do Bom Jesus, localizado no município de Serra Talhada – PE. No bairro foram identificados 19 pontos de descarte irregular desses resíduos, os mesmos foram classificados conforme a classificação do CONAMA. A identificação dos locais de descarte irregular dos RCD’s serve como alerta aos órgãos púbicos para ajudar na promoção de uma maior fiscalização e de políticas públicas que atuem contra esse tipo de destinação à esses resíduos.
A short history of the successes and failures of the international climate change negotiations
Authors: Maslin Mark , Lang John , Harvey Fiona
Published: December 2022

The last 30 years have been a period of intense and continuous international negotiations to deal with climate change. During the same 30 years, humanity has doubled the amount of anthropogenic carbon dioxide in the atmosphere. There has, however, been progress and some notable successes in the negotiations. In 2015, at the 21st Conference of the Parties (COP21) to the United Nations Framework Convention on Climate Change (UNFCCC), 196 countries adopted the Paris Agreement stating that they would limit global temperatures to well below 2°C above pre-industrial levels and would pursue efforts to limit the temperature increase to 1.5°C above pre-industrial levels. The first review of the Paris agreement was at COP26 in Glasgow with many countries pledging to go net zero emissions by the middle of the century. But currently these pledges, if fulfilled, will only limit global average temperature to 2.4˚C to 2.8˚C. At COP27 in Egypt the core agreements from the Glasgow Climate Pact were maintained and countries finally agreed to set up a Loss and Damage facility – though details of who finances and who can claim are still be to be worked out. This article reviews the key moments in the history of international climate change negotiations and discusses what the key objectives are for future COP meetings.
Editorial
Authors: Pessôa Ana Carolina Rocha , Tuzzo Simone Antoniaci
Published: December 2022

O conjunto de atividades relacionadas com as mídias, e particularmente com o jornalismo, tem como uma das suas características estarem em permanente crise e, portanto, em permanente renovação. Parte desse tensionamento é consequência de sua simbiose com as técnicas e tecnologias que envolve a produção dos conteúdos midiáticos, mas também pela compreensão da responsabilidade que envolvem os veículos midiáticos, mas também pela busca para compreendermos melhor essas atividades. Isso não acontece por acaso, o acesso democratizado aos conteúdos jornalísticos é uma condição essencial para a cidadania e o exercício dos direitos políticos nas democracias contemporâneas. A vida cotidiana nos espaços dominados pela centralidade da vida urbana, com todas as suas angústias e contradições, exige o contato sempre renovado com informações atuais e confiáveis.O jornalismo, atividade guiada pela práxis e pela ética, é um espaço de mediação que lança uma nova forma de olhar o cotidiano, mas que também atua sobre diferentes espaços que afetam as atividades humanas. O jornalismo pressiona o Estado, as instituições e até mesmo a formação e atuação de grupos sociais e políticos. Ao mesmo tempo, porém, o jornalismo é também é pressionado por diferentes forças, em uma relação que altera tanto a produção jornalística quanto seus conteúdos.
Feline progressive histiocytosis in four cats: case reports
Authors: Kim Ji-Su , Yim So-Jeong , Kim Jae-Hoon , Jung Ji-Youl
Published: December 2022

We describe four cases of feline progressive histiocytosis (FPH) including three females (one intact, two spayed) and one castrated male cat, with a mean age of 5.95 years at diagnosis. Masses were found under the skin of head, lip, neck, and vulva. Histologically, proliferative round cells had ovoid nuclei, foamy eosinophilic cytoplasm, distinct cytoplasmic processes, and mitotic figures. Immunohistochemically, all cases were positive for Iba1 and MHC II (Dako). One case showed cytoplasmic positive staining for E-cadherin. To the best of our knowledge, this is the first documented report of FPH in Korea.
Moderating Effect of Perceived Behavioural Control on Tourists’ Revisit Intention in Island Tourism Industry: A Conceptual Model
Authors: ROSLI Nur Akmal , ZAINUDDIN Zaliha , YUSLIZA Mohd Yusoff , MUHAMMAD Zikri , SAPUTRA Jumadil , NORDIN Aleff Omar Shah , HAMID Shahriman Abdul
Published: December 2022

Seeking enjoyment or pleasure through travelling has been known to reduce stress and improve emotional well-being. However, the prolonged global pandemic and its negative affect have impacted tourists’ travel behaviour and intention. Hence, it is necessary to investigate how and to what extent emotional well-being influences revisit intention. Since studies regarding this topic in the context of island tourism are scarce, the current study extended the TPB model by proposing the influence of positive affect on tourists’ revisit intention to coastal tourism destinations. Moreover, this work explored the moderating role of perceived behavioural control (PBC) on attitude, subjective norms, and behavioural intention. This study enriches the tourism literature related to coastal tourism and tourists’ decision making process. The findings provide useful insights for policy makers and practitioners in the field of the tourism industry and human behaviour.
The Determinants of Loyalty to Ecotourism against the Background of Consumer Satisfaction
Authors: HOANG Sinh Duc , NGO Ngoc Thuyen , NGUYEN Diep T.N. , NGUYEN Thi Thu Huong , TUČKOVÁ Zuzana
Published: December 2022

The desire to gain knowledge about the cultural identity and nature of unexplored places has been inherent in humans since time immemorial. However, the emergence of motivation to care, preserve and increase the cultural, historical, natural and recreational values of destinations indicates a higher level of consciousness and responsibility of tourists. The commitment of tourists to this kind of travel is caused not only by marketing prerequisites, but also by socio-psychological factors different: responsibility, psychological ownership. Due to international competition, the relevance of improving the tourist image is increasing, for which it is necessary to develop the concept of socially and environmentally responsible tourism, develop useful behavioral attitudes in society, which increases the role of transfer of cultural and natural knowledge, consolidation of tourists and local residents in improving the tourist image. The study considers the construct of loyalty to a particular destination. The aim of the study is to deepen the analysis of socio-psychological factors of loyalty to ecotourism and develop a methodology for their study. On the basis of correlational, empirical and sociological methods the direct correlation between loyalty and responsibility, satisfaction, positive experience, psychological property and image of the destination was substantiated. It is proved that research activity, intellectual preparation, motivation, respect for nature, cultural involvement and involvement of local residents have a positive effect on the level of responsibility. Cultural involvement and protection of nature, psychological attachment and social interaction increase the sense of psychological ownership, in contrast to the massiveness factor of the place, which decreases it.
Smart Technology Effecting Tourism Development in Albania
Authors: MUÇA Etleva , BOBOLI Irena , KAPAJ Ilir , KAPAJ MANE Ana
Published: December 2022

The concept of tourism represents a wide field of research and development, especially considering the global dimensions it is taking. In Albania, the tourism sector has become one of the most important sectors of economic development, especially in recent years when attention has increased in the international arena. The financial and social impact has begun to be experienced, when seeing that almost all figures in the tourism components show growth. The earthquake of November 26, 2019, and especially the isolation from the COVID-19 pandemic, had a negative impact, that limited the development and investment capacities in this sector. As a result of the great opportunities that our country offers in the field of tourism, technology has played a no less important role, especially for promotion to foreigners. The standardization of services has come as a result of awareness on development opportunities, but also as a result of constant demands and models borrowed from other countries, where digital transformation also undoubtedly plays a role. Another element affected in this study is the digitalization of business in the provision method of the tourism product. Specifically, tel_Albania, as a leading company in the country, has launched the tel_Business platform, by aiming to contribute to the fulfilment of the concepts of smart tourism and e-tourism.
Shariah-Based Hospitality, Competitive Advantage and Tourists’ Revisiting Interest on Indonesia Tourism
Authors: NASIR Abdul , WARIDIN Waridin , ISKANDAR Deden Dinar , SUSILOWATI Indah , HIDAYAT Abas
Published: December 2022

Along with the increase in tourist destinations, hotels also increase, ranging from cheap to expensive ones. The promotion of the hotel was well done. However, the low quality of service resulted in the hotel losing guests. Excellence in the hospitality promotion sector is part of the hotel industry's success. For Muslim-majority countries, one of the influential factors in hotel selection is the Halal brand. This study aims to investigate the effect of Sharia-based hospitality hotels on competitive advantage and tourists' revisiting interest. This study uses the method of the Structural Equation Model (SEM). There were 140 respondents consisting of guests, staff, and managers of Shariah hotels in West Java, Indonesia. The sampling technique used in this research was purposive sampling. Hypothetical testing results showed that Shariah-based hospitality hotels significantly affect competitive advantage and tourists' revisiting interest. The competitive advantage significantly affects tourists' revisiting interests. Shariah-based hotel hospitality's creativity and innovation create superior competitiveness and foster interest in staying again. Shariah hotel marketing is not just advertising in digital media but also paying attention to customer feedback.
Knowledge Map of Chinese Tourists Travelling to Thailand: Based on the Bibliometric Method
Authors: FU Haiying , SUTUNYARAK Chonlavit
Published: December 2022

Chinese tourists have essential economic and cultural exchange values for Thai tourism. The present research on Chinese tourists traveling to Thailand (CTTT) has made a significant breakthrough, but it rarely observes the research status quo, hot spots, and the future based on bibliometric methods and visualization technology. Based on 710 articles on the Web of Science (WoS), Cite Space visualization technology was used to analyze the publishing trend of CTTT, authors, institutions, countries, keywords, and categories, and build a knowledge map about CTTT. The study found that although the positive trend of published articles indicates excellent future development, the overall number of published articles is not ideal. Moreover, research on this topic has made significant progress and breakthroughs in the healthcare field, meaning that there is still much research space in the business and economic areas. Thai institutions and scientific research institutions and their scholars have significantly contributed to CTTT. They focus more on healthcare, disease, health, sexual safety, and equality in travel. Although there is an increasing focus on consumer behavior, habits, and models, However, the research on CTTT under the background of the digital economy, sharing economy, big data, artificial intelligence, and the COVID-19 pandemic is of great research value. Therefore, this study encourages different countries, institutions, and scholars to do more on this topic. Furthermore, interdisciplinary research is even more critical.
Financial and Administrative Measures for the Development of Tourism after COVID-19
Authors: AISIN Marat Zh. , AITKAZINA Madina , MAULINA Nurgul Hasanovna , ZHAKIPBEKOV Dinmukhamed Saparovich , SAPAROVA Gulnara Telmanovna
Published: December 2022

The recent decades demonstrate that tourism is one of the sectors that develop the most consistently and form the backbone of the economies of many developed and developing countries. In this context, one of the main problems hindering the promotion of tourism services is the relatively high probability of force majeure situations. Whereas forced flight cancellations, floods, or hurricanes are local events, the consequences of the COVID-19 pandemic have taken their toll on the entire tourism sector. Today, the tourism sector is one of the most affected by the COVID-19 pandemic. This may provoke further regression given the weak global economy, geopolitical, social, and trade tensions, and uneven performance among major outbound travel markets. At the same time, over many years, tourism has been consistently proving its resilience and ability not only to recover from economic crises but also to contribute to a broader economic and social recovery. The goal of the present study is to develop proposals for the introduction of financial and administrative measures for the development of the tourism industry in the post-pandemic period. Data for the study are collected by means of document analysis and an expert survey. The study concludes that in order to overcome the adverse economic effects of the COVID-19 pandemic in the sphere of tourism, a number of financial and administrative measures need to be developed and implemented at the level of state and local government institutions, particularly in Kazakhstan, to support the development of the tourism sector and stimulate the activities of tourism enterprise. For their part, the authors propose the key measures that should improve the financial sustainability and organization of the tourism sector in Kazakhstan.
The Online Reputation of Tourism Brands and Their Dependence on Pandemic Scenarios: An Analysis of the "Hospederías De Extremadura" Brand before and during COVID-19
Authors: SÁNCHEZ RIVERO Marcelino , MURILLO GONZÁLEZ Luis , RODRÍGUEZ RANGEL María Cristina
Published: December 2022

New technologies are having a decisive influence on the behaviour of tourists. Nowadays, all tourists search information on the internet before enjoying any service offered by tourism companies. Consequently, online reputation is an essential component in the marketing strategy of tourism brands. On the other hand, the Covid-19 pandemic has revolutionized tourism activity since its emergence in March 2020. Its direct effects have been widely studied in the literature, but no studies have yet been conducted on the effects of this pandemic on the online reputation of tourism brands. The aim of this paper is to empirically test whether this effect exists and if so whether it has been positive or negative. For this purpose, the weekly time series between January 2017 and September 2020 of ReviewPro's Global Review Index (GRI) were analyzed for 5 of the 8 accommodation which represent "Hospederías de Extremadura" tourism brand. To achieve the objectives of this paper, a pre-Covid period and a Covid period were considered and both the median values of the GRI and the trends in both periods have been compared. The results obtained demonstrate the disruptive character that the pandemic has had on the online reputation of tourism brands.
Is Functional Connectivity after a First Unprovoked Seizure Different Based on Subsequent Seizures and Future Diagnosis of Epilepsy?
Authors: Koo Ga Eun , Jeong Ho Tae , Youn Young Chul , Han Su-Hyun
Published: December 2022

Background and Purpose: There are no highly sensitive biomarkers for epilepsy to date. Recently, promising results regarding functional connectivity analysis have been obtained, which may improve epilepsy diagnosis even in the absence of visible abnormality in electroencephalography. We aimed to investigate the differences in functional connectivity after a first unprovoked seizure between patients diagnosed with epilepsy within 1 year due to subsequent seizures and those who were not.Methods: We compared quantitative electroencephalography power spectra and functional connectivity between 12 patients who were diagnosed with epilepsy (two or more unprovoked seizures) within 1 year and 17 controls (those not diagnosed within 1 year) using iSyncBrain® (iMediSync Inc., Suwon, Korea; https://isyncbrain.com/). In the source-level analysis, the current distribution across the brain was assessed using the standardized low-resolution brain electromagnetic tomography technique, to compare relative power values in 68 regions of interest and connectivity (the imaginary part of coherency) between regions of interest.Results: In the epilepsy group, quantitative electroencephalography showed lower alpha2 band power in left frontal, central, superior temporal, and parietal regions and higher beta2 power in both frontal, central, temporal, occipital, and left parietal regions compared with the control group. Additionally, epilepsy patients had significantly lower connectivity in alpha2 and beta2 bands than the controls.Conclusions: Patients experiencing their first unprovoked seizure presented different brain function according to whether they have subsequent seizures and future epilepsy. Our results propose the potential clinical ability to diagnose epilepsy after the first unprovoked seizure in the absence of interictal epileptiform discharges.
Isolated Unilateral EEG Findings in Juvenile Myoclonic Epilepsy: A Case Report
Authors: Suzgun Merve Aktan , Demirbilek Veysi
Published: December 2022

Juvenile myoclonic epilepsy (JME) has well-defined clinical and electrophysiological features. On the other hand, large case series have shown that focal and asymmetrical discharges may accompany generalized epileptiform activities in JME. Although it is known that these non-generalized electrophysiological findings do not exclude the diagnosis of this syndrome, some findings may create confusion in the differential diagnosis. In this case report, a case of JME with electroencephalographic findings characterized by isolated unilateral epileptiform activities without typical generalized discharges was discussed. The current case clinically presented with involuntary jerk movements in the bilateral upper extremities. It has been determined that these movements are uni/bilateral myoclonic beats based on home video recordings. Metabolic, toxic and structural problems were excluded in the investigations for the etiology of myoclonus. In the electrophysiological examination performed for epileptic processes, epileptiform discharges localized to the isolated right hemisphere were observed. JME was considered primarily due to clinical findings in the patient, and effective seizure control was achieved in a 4-year follow-up under anti-seizure treatment. The peculiarity of the case is the presence of electrophysiology recordings of isolated unilateral epileptiform activity during the 4-year follow-up period. It should be emphasized that there is no case of JME diagnosed with isolated unilateral epileptiform activity in the absence of generalized spike-slow waves or multiple spike-slow waves in the literature.
The Increased Interleukin-6 Levels Can Be an Early Diagnostic Marker for New-Onset Refractory Status Epilepticus
Authors: Kwack Dong Won , Kim Dong Wook
Published: December 2022

New-onset refractory status epilepticus (NORSE) is a condition defined as the occurrence of refractory status epilepticus in patients without active epilepsy and no other acute causes of seizure. Although there is evidence that immune-mediated pathogenesis has a pivotal role in the epileptogenesis of NORSE, the diagnosis of NORSE is usually made on the clinical observation because there is no established biological marker suggesting the diagnosis of NORSE. We recently encountered a NORSE patient who was successfully treated with immunotherapy including tocilizumab, an anti-interleukin-6 (IL-6) receptor monoclonal antibody, and the markedly increased levels of serum and cerebrospinal fluid IL-6 were the only laboratory abnormality during the early treatment of the patient.
Cerebral Salt Wasting Syndrome Associated with Status Epilepticus
Authors: Lee Jung-Ju
Published: December 2022

Cerebral salt wasting syndrome (CSWS) is defined as a renal loss of sodium in cerebral disorders causing hyponatremia and loss of extracellular fluid volume. Similar laboratory findings may be seen in other conditions such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). A 58-year-old male visited our emergency department because of the sudden development of seizures during sleep. Magnetic resonance imaging revealed subtle high signal intensity in the right hippocampus on diffusion-weighted imaging. Ictal rhythmic discharges were observed in the concordant area. Altered metal status, polyuria and laboratory test findings including hyponatremia were compatible with CSWS. After hydration and salt replacement, his mental state and hyponatremia gradually recovered. For diagnosing CSWS, meticulous physical examinations including analysis of fluid balance are essential. CSWS should be considered in patients with hyponatremia and polyuria. Accurate diagnosis of CSWS and SIADH is crucial as the treatment plans for these two conditions are completely different.
Clinical Profile and Predictors of In-Hospital Mortality in De Novo Convulsive Status Epilepticus in the Elderly Populace
Authors: Verma Archana , Kumar Alok , Pathak Pooja , Mishra Ashutosh Kumar
Published: December 2022

Background and Purpose: De novo status epilepticus (SE) had worse outcome in comparison to the patients with SE who had previous history of epilepsy. The aim of the present study was to identify clinical features of de novo convulsive status epilepticus (CSE) and the predictors of in-hospital mortality.Methods: Seventy-seven elderly (≥60 years of age) hospitalized patients with de novo CSE were evaluated for clinical profile, aetiologies and predictors of in-hospital mortality.Results: The average age of the participants in the study was 65.96±6.72 years. In de novo CSE, the most common aetiologies were acute symptomatic in 68.8% of cases, followed by remote symptomatic in 24.7%. In-hospital mortality in the de novo CSE in the elderly was 30 (38.9%) in our series. Stroke was the leading cause of death among them (acute stroke in 23 cases and old infarct in 1 case), followed by post-traumatic (n=4) and CNS infection (n=2). On multivariate analysis, it was found that variables significantly related to mortality in de novo CSE were low Glasgow coma scale (GCS) (adjusted odds ratio [AOR], 53.5; 95% confidence interval [CI], 5.17-555.14; p=0.001) and lack of response to first line treatment (AOR, 0.06; 95% CI, 0.01-0.50; p=0.01).Conclusions: In-hospital mortality in de novo CSE patients was linked to a low GCS and a lack of response to first-line therapy. The most efficient strategy to prevent in-hospital mortality in the elderly is to treat de novo CSE promptly and aggressively in the setting of stroke.
Interconnectivity of the Vardar and Struma river valleys. Some hints to the understanding of the south-eastern Balkans role in the 2nd millennium BC
Authors: Bahyrycz Cezary
Published: December 2022

The Vardar and Struma rivers flow through the south-eastern Balkans, creating valleys which have been inhabited by human populations for thousands of years. From an archaeological perspective, from Neolithic times these corridors have long been considered crucial for establishing cultural, trade, and social networks, developed later by the emergence of cultural complexes of Late Bronze Age. This area was incorporated into wide archaeological frameworks of interregional interaction, namely – the world-system theory and its variants. The aim of this paper is an attempt to apply these theoretical models as well as concept of “contact space” to human interactions in the Vardar and Struma rivers’ valleys in the 2nd millennium BC. It analysis bases on tableware pottery evidences with data concerning presence of defensive outposts within easy to control mountainous paths, as well as chosen information deriving from funeral rites. These data may provide insights into the communication networks in south-eastern Balkans and mentioned river valleys may seem as an important area of mutual influences.
CYP2C9 gene polymorphisms influence on antihypertensive effectiveness and hypouricemic effect of losartan among patients with arterial hypertension: an observational study
Authors: Sinitsina Irina I. , Boyarko Alexey V. , Temirbulatov Ilyas I. , Sychev Dmitry A. , Akmalova Kristina A. , Sozaeva Zhannet A. , Grishina Elena A. , Mirzaev Karin B. , Asoskova Anastasiia V. , Fisenko Vladimir P.
Published: December 2022

Objectives

CYP2C9 gene polymorphic variants can decrease the effects of losartan, reducing active metabolite (E-3174) formation. Study aims to determine the influence of *2 (+430C>T; rs799853) and *3 (+1075A>C; rs1057910) CYP2C9 gene polymorphic variants on the hypotensive and uricosuric effect of losartan on patients with arterial hypertension.

Methods

Eighty one patients with stage 1–2 arterial hypertension newly diagnosed with ABMP were enrolled in the study. Physicians started losartan treatment and then we measured urine concentration of E-3174/losartan to estimate CYP2C9 activity. After 3-month losartan treatment we compared effectiveness of the therapy with ABPM and plasma uric acid level between carriers of CYP2C9 *1/*1 and CYP2C9 gene polymorphic variants (*2 and *3).

Results

Carriage of CYP2C9*2 and CYP2C9*3 alleles reduced the hypotensive effect of losartan (p<0.001, OR=8.13 (95% CI, 2.75–23.97)). Analysis of the ABPM data revealed that blood pressure was significantly higher in patients with polymorphic genotypes. There was no significant difference in uric acid level in plasma and losartan and its metabolite concentration in urine between genotypes.

Conclusions

Carriage of low function polymorphic variants of the CYP2C9 gene (*2 and *3) reduced the hypotensive effect of losartan according to ABPM and don’t affect uric acid level in plasma and E-3174/losartan in urine.
Quantitative assessment of antioxidant potential of selected homeopathic preparations in clinical practice
Authors: Kumar Arun , Prajapati Suneel , Sharma Mahima , Singh Tejveer , Choudhary Neha , Bharti Alok C. , Sharma Rohit , Gupta Pankaj
Published: December 2022

Objectives

Antioxidant property like radical scavenging is a primary target to elucidate the efficacy mechanism of a drug against diseases linked to oxidative stress such as cancer, metabolic disorders, rheumatoid arthritis, etc. In alternative therapies, homeopathy is one of the preferred choices by patients and clinicians due to its potential to cure chronic and complex illnesses. However, the efficacy of homeopathic preparations at high diluted potencies attracts rational criticism due to insufficient scientific knowledge supporting the mechanism of action. Therefore, an attempt was made to estimate the total phenolic content (TPC) and radical scavenging activity of clinically prescribed homeopathic drugs.

Methods

With gallic acid as a reference control, mother tinctures (MTs) and different potencies of Eucalyptus globulus (EG), Syzygium jambolanum (SJ), Ruta graveolens (RG), and Thuja occidentalis (TO) were used to perform Folin–Ciocalteu test, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays.

Results

The results showed TPC of MTs equivalent to µg/mL of gallic acid viz; EG (4,872.5 ± 133.2), SJ (8,840.5 ± 14.8), RG (985.6 ± 39.1), and TO (341.5 ± 19.5) with significant ABTS and DPPH radical scavenging potential. Whereas 30C and 200C potencies of each homeopathic drug showed undetectable phenolic content and insignificant radical scavenging potential compared to vehicle control, i.e., alcohol 90% (2.0 ± 1.5).

Conclusions

The reported efficacy of 30C and 200C potencies of homeopathic medicines against oxidative stress-related illnesses might be due to mechanisms other than radical scavenging. Furthermore, the assays studied can be helpful in drug standardization and quality control of MTs that are used as starting material in homeopathic preparations.
Nonlinear wavelength conversion cross phase modulation in fiber systems based on directly modulated laser measured
Authors: Rashed Ahmed Nabih Zaki , Babu Gade Harish , Ahammad Shaik Hasane , Sorathiya Vishal , Hossain Md. Amzad , Daher Malek G. , Ahmed Shimaa Ali
Published: December 2022

This study has clarified the simulation of the nonlinear cross phase modulation (CPM) performance signature in optical fiber telecommunication systems. We have been clarified the max Q factor in relation to Cross phase shift modulation for the previous models and proposed model. The optimum optical power varied with spectral time and wavelength variation that is simulated for 90° cross phase shift modulation. Optimum total optical and electrical signal power is demonstrated for 90° Cross phase shift modulation. The max signal quality factor and min BER are assured for various degrees based on cross phase shift modulation. In addition to the optimum signal quality factor is emphasized for 90° Cross phase shift modulation.