bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis and anti-microbial evaluation with in silico studies of novel 2-aminothiazole benzohydrazide derivatives
Authors: Amrutha S. , Das Paramita , Nayak Anjali , Laha Supratip , Begum Sharmina , Bhardwaj Sakshi
Published: January 2025

Background

The development of novel anti-microbial drugs for multidrug-resistant (MDR) is a significant challenge. This study aimed to synthesize various derivatives of (Z)-4-(2-aminothiazol-5-yl)-N-benzohydrazide (DT01-DT10) that are effective against a wide variety of anti-bacterial and antifungal pathogens.

Results

The binding energy of the compounds ranged from − 9.0 to − 10.0 kcal/mol. Molecular simulations produced a major result in improving the representation of the real biological conditions with an average RMSD of 0.110 nm. The derivatives DT03, DT04, and DT06 showed overall good anti-microbial activity at lower concentrations of 1.8 µg/ml. Compound DT03 showed significant activity against Gram-positive, Gram-negative bacteria and fungal strains, with inhibition zone diameters of 17, 19 and 16 mm, respectively. Compound DT04 showed promising anti-bacterial effects against S.mutans and C.albicans, with inhibition zone diameters of 18 and 17 mm, and moderate activity against B. cereus. Compound DT06 showed enhanced activity against P.aeruginosa.

Conclusion

The derivative 4-(2-amino-1,3-thiazol-5-yl)-N′-(Z)-(2-nitrophenyl) methylidene benzohydrazide (DT06), which contained a nitro group displayed potent activity at 1.8 µg/ml with an IC50 of 50.31 and a selectivity index of 61.33.

Graphical abstract
Investigating the pre- and post-COVID-19 vaccination infection status of Iranian dental students: a cross-sectional study
Authors: Owlia Fatemeh , Kargar Mohammad-Javad , Kazemipoor Maryam
Published: January 2025

Background

Dental students face a potential risk of COVID-19 exposure due to close patient contact and aerosol-generating procedures. This study explores the frequency of COVID-19 infection among Iranian dental students in 2022 following different vaccination doses.

Methods

A cross-sectional study was used to collect self-reported COVID-19 status. A total of 261 dental students volunteered to participate in the study. A total of 252 valid forms were gathered, with a response rate of 96.55%. Data analysis was performed using descriptive statistics, mean and standard deviation, and chi-square and Fisher exact tests by Spss17 (Chicago, USA) software.

Results

The rate of COVID-19 infection significantly decreased after the first and third doses of vaccination. The rate of COVID-19 infection was not very different after the first, second, and third doses of the vaccine according to the type of vaccine. Despite no significant difference in COVID-19 infection rates between genders, study years, or vaccine types (excluding AstraZeneca), participants who received the AstraZeneca vaccine experienced more serious side effects compared to those who received other vaccines.

Conclusion

Vaccination appeared to reduce the rate of COVID-19 infection among dental students and may have decreased the duration of infection following different vaccine doses. There was no significant difference in infection rates based on the type of vaccine received. Further research is needed to investigate the potential side effects and long-term effectiveness of COVID-19 vaccines.
The impact of the live broadcast of Stromae’s song L’enfer on social media publications, calls to the national helpline, and suicide attempt rates in France
Authors: Notredame Charles-Edouard , Saint-Dizier Chloé , Lamer Antoine , Nogue Erika , Fares Emile , Lemdani Mohamed , Vaiva Guillauma , Courtet Philippe , Olié Emilie
Published: January 2025

On January 9, 2022, Belgian pop singer Stromae performed his new hit “L’enfer” live on French TV. The song addresses his personal struggles with suicidal ideation. To evaluate the impact of Stromae’s performance, we modeled the evolution of hospital admission rates for suicide attempts (SAs) in France, calls to the national suicide prevention helpline (3114), and Twitter publications mentioning the singer or the helpline. We employed the Gombay test to identify change points within each time series. We identified a significant increase in mean SA rates among women aged 20–24 years 6 days after the singer’s performance. No similar effect was observed in the general population or other young age groups. The show was immediately followed by a peak in tweets referring to the singer, while Twitter activity related to the 3114 remained modest. We did not observe any increase in calls to the helpline. Celebrity testimonies about suicidal experiences can help alleviate stigma but should be accompanied by prevention messages to reduce the risk of contagion.
Food for Cancer Health Equity: A Qualitative Study Among People With Cancer Who Are Low-Income, Latino or Hispanic, Immigrant, and Individuals With Multiple Minoritized Races and Ethnicities
Authors: Hanna Maria , Wood Emily H. , Noyola Perez Andrés , Villicana Gerardo , Guzman Lesly Lopez , Reynaga Jajaira , Trotter Chardria , Koontz Zachary M. , Patel Manali I.
Published: January 2025

PURPOSE

Food insecurity is prevalent among patients with cancer. Gaps in our understanding of preferences for food assistance among Latino or Hispanic, immigrant, and people with multiple races and ethnicities limit uptake of food assistance interventions among these populations. We aimed to deeply understand the needs and preferences and barriers to food assistance intervention uptake among low-income, predominantly Latino or Hispanic, immigrant, and people with multiple races and ethnicities and cancer to inform development of tailored interventions.

METHODS

Participants were recruited among low-income adult patients with cancer who screened positive for food insecurity using the two-item Hunger Vital Sign as part of an ongoing parent randomized controlled trial evaluating a precision medicine intervention. Semi-structured interviews were conducted to assess dietary habits, barriers to food security, and preferences for intervention. Interview responses were transcribed, translated, and thematically analyzed using an inductive-deductive iterative approach.

RESULTS

Among 40 (36.4%) participants in the parent randomized trial who screened positive for food insecurity, 20 (50%) were randomly selected to participate in this study. The mean age of participants was 56 years, 17 (85%) self-identified as Latino or Hispanic, 17 (85%) identified Spanish as their preferred language, 13 (65%) reported annual household income <$34,000 in US dollars, and 12 (60%) were unemployed. Three main themes emerged: (1) individualized nutritional needs and culturally specific food preferences; (2) financial, logistical, and emotional barriers to food security; and (3) self-efficacy, autonomy, and approaches to reduce stigma in food assistance interventions.

CONCLUSION

Assessing and integrating the needs and preferences for food assistance is crucial for the development and uptake of food assistance interventions among Latino or Hispanic, immigrant, and other racial and ethnic minoritized individuals with cancer.
Comparative Effects of Different Exercise Types on Cardiovascular Health and Executive Function in Sedentary Young Individuals
Authors: Huang Jinglin , Leng Lu , Hu Min , Cui Xuyan , Yan Xu , Liu Ziqing , Wang Kangle , Wu Jiarui , He Shan , Deng Weiji , Li Peilun , Chen Yilin , Gao Dongdong , Wei Yuan , Huang Junhao
Published: January 2025

Purpose

The present study aimed to compare the impacts of different exercise types on cardiovascular health and executive function in sedentary young individuals, and to determine the associations between cardiovascular function and executive function (EF) after exercise.

Methods

Sixty-three sedentary participants were randomly divided into high-intensity interval training (HIIT), moderate-intensity continuous training (MICT), resistance exercise (RE), and control groups. Macro- and microvascular endothelial function were assessed using brachial artery flow-mediated dilation and fingertip reactive hyperemia index, respectively. Arterial stiffness was evaluated through carotid-femoral pulse wave velocity, ankle-brachial index, and augmentation index. EF performance was evaluated using the Stroop and N-back tasks. Functional near-infrared spectroscopy was employed to measure cortical activation and real-time oxyhemoglobin concentration (Oxy-Hb) changes in different cerebral regions. Key circulating biomarkers for vascular and cognitive function, including BDNF, irisin, VEGF, IGF-1, and TNF-α, were measured using enzyme-linked immunosorbent assays.

Results

Eight weeks of HIIT, MICT, and RE effectively improved macro- and microvascular endothelial function while reducing arterial stiffness in sedentary young individuals. Furthermore, exercise-induced increase in BDNF level was correlated with enhanced macrovascular endothelial function, while increase in IGF-1 level was associated with enhanced microvascular endothelial function and reduced arterial stiffness. Notably, both HIIT and MICT, but not RE, efficiently enhanced Oxy-Hb level in certain brain regions, such as the FPA and DLPFC, leading to the improvement in EF performance. Exercise-induced increase in Oxy-Hb level and EF performance were correlated with enhanced BDNF level and endothelial function and reduced arterial stiffness.

Conclusions

Our study demonstrated that 8 weeks of HIIT, MICT, and RE effectively improved endothelial function in both macro- and microvessels, and arterial stiffness among sedentary young individuals. However, HIIT and MICT, but not RE, notably increased blood oxygen level in the FPA and DLPFC brain regions and improved EF performance. Due to the efficiency and time-saving features of HIIT, the present study highlights HIIT as an effective exercise prescription for promoting vascular and EF in sedentary young individuals. Importantly, the observed improvements in cardiovascular function following exercise training is pivotal in improving EF, and elevated circulating levels of biomarkers like BDNF and IGF-1, induced by exercise, are involved in the regulatory mechanisms.
Boutique do Pão de Ló: a verdadeira essência, mesmo à distância
Authors: Jardim Alves de Oliveira Rômulo , Besen Fronza Tânia Cristina , Lana Jailson , Beal Partyka Raul
Published: January 2025

Este caso de ensino descreve o dilema de expansão da Boutique do Pão de Ló. A empresa que começou um food truck, tornou-se marca reconhecida em toda região. Um modelo de negócio foi estruturado com foco em atrair o cliente até a loja física. Atualmente, o ponto chave para a evolução da empresa está em decidir quais os parâmetros para uma expansão em forma de franquia. Neste caso são destacadas análises de mercado, desenvolvimento estratégico e demográfico para que a análise da criação de franquias mostre se é viável neste momento para a empresa no cenário atual.
“Foi só uma brincadeirinha”: caso de ensino sobre violação de direitos no ambiente de trabalho
Authors: Vitorassi Ana Julia , Imaizumi Eric Gabriel , Leão Oderich Cecília , Spack Kemmelmeier Carolina
Published: January 2025

O presente caso de ensino apresenta o dilema que a empresa Millers enfrenta de como restaurar a imagem interna e externa do após três ações trabalhistas de assédio impetradas por funcionários sem o conhecimento dos proprietários. A empresa de pequeno porte localizada no Oeste do Paraná foi criada por Tadeu, que tinha o objetivo de ser “seu próprio patrão”. Com o passar dos anos, Maria, sua filha mais velha, interessou-se por continuar o legado do pai e tomar a frente da gestão. Durante o período em que Maria realizava graduação em Administração, seu pai adoeceu e deixou a gestão da empresa nas mãos de seu gerente de confiança, realizando o acompanhamento da empresa apenas a partir da receita arrecadada. Quando Maria conclui a graduação, ela e o pai se deparam com ações trabalhistas de assédio sexual, assédio moral e assédio eleitoral contra a Millers. O caso descrito foi desenvolvido com o objetivo de fixar conteúdos relacionados a desafios de recursos humanos, direito trabalhista e administração de empresas, sendo pertencentes às vertentes de graduação em Administração e Direito. A história foi construída a partir de pesquisa bibliográfica e pesquisa documental em sites oficiais com informações sobre processos trabalhistas já divulgados que ocorreram no Oeste do estado do Paraná.
Do reporting guidelines improve the efficiency and quality of radiological case reports writing? A study protocol
Authors: Wang Mengshu , Luo Xufei , Zhao Junxian , Liang Tianhu , Xu Dan , Yang Shu , Zhou Zhirui , Feng Xixi , Xiao Xiaojuan , Song Fujian , Tian Jinhuii , Lv Han , Lei Junqiang
Published: January 2025

Background Radiological case reports summarize the imaging characteristics of individual cases to identify patterns and valuable lessons. Their writing can be guided by the CARE reporting guidelines or the CARE-radiology reporting guidelines. However, the impact of following these guidelines, or not following them, on the quality and efficiency of radiological case reports writing remain unclear. Objective To examine whether following the CARE reporting guidelines or the CARE-radiology reporting guidelines, or not following any reporting guidelines, affects the quality and writing efficiency of radiological case reports. Protocol The purpose of this protocol is to outline the background and objectives of this study, as well as the design of a cluster randomized controlled trial (cRCT). We will design a three-arm, multicentre cRCT, targeting radiologists or radiology students from different medical institutions. The intervention include training on the CARE-radiology checklist; the second intervention involves training on the CARE checklist. The control group will follow standard procedures without any intervention. After the intervention, participants will be required to write a case report within a period of 10 days. The primary outcome measures will be the completeness and clarity of the case reports. Discussion This study aims to enhance the adherence of researchers to reporting guidelines for case reports through rigorous design. The results will be further explained and interpreted in the final trial outcomes. Registration This study has been registered with the Chinese Clinical Trial Registry, with the registration number: ChiCTR2400089973.
Support Vector Machine-Based Prediction Model for Healthcare Workforce Transition Success Under Decentralization
Authors: Sarakshetrin Atiya , Sujimongkol Chinakorn , Rongmuang Daravan , Chantra Rungnapa , Nimwatanakul Suchada
Published: January 2025

Objective To develop predictive models for healthcare workforce transition success under decentralization using Support Vector Machine (SVM) analysis and identify key determinants across organizational support domains. Methods A cross-sectional study was conducted among healthcare personnel (n=430) who transferred from Ministry of Public Health facilities to Provincial Administrative Organizations in Thailand during 2023-2024. The SVM model evaluated 37 predictor variables spanning demographic characteristics, benefits, and welfare domains. Four kernel functions were compared to identify optimal model performance, and feature importance analysis was conducted to determine key predictors. Results The linear kernel demonstrated superior performance (accuracy: 71.43%, sensitivity: 49.02%, specificity: 85.37%) compared to other kernel functions. Analysis revealed five key predictors (feature weights >0.25): competitive compensation (0.427), career development opportunities (0.358), fair promotion processes (0.336), hazardous work compensation (0.285), and educational leave opportunities (0.252). While employee qualifications (0.236) emerged as a significant demographic predictor, organizational support factors, particularly financial incentives and professional development opportunities, showed stronger predictive power for transition success. Conclusions This study represents the first application of machine learning techniques to predict healthcare personnel transition success in decentralization contexts. The SVM model effectively identified critical factors influencing workforce transitions, emphasizing the importance of balanced organizational support mechanisms. These findings provide evidence-based guidance for healthcare administrators implementing decentralization policies, offering generalizable insights for workforce management during health system reforms.
Incretin hormone agonists as promising antiobesity drugs - review of literature
Authors: Grzegorczyk Aleksandra , Korus Justyna , Dziedziak Marta , Dardzińska Nicol , Hopej Natalia
Published: January 2025

The aim of this work is to draw attention to the recently growing problem of obesity and complications related to it. Dietary recommendations and recommendations regarding physical activity turned out not to show satisfactory effects in patients with obesity in terms of weight loss, but also in maintaining the effects of the actions taken. The basic basis of the problem turned out to be much more complicated. It is not only related to the occurrence of a positive energy balance, but also to the dysfunction of the entire organism. The discovery of incretin hormones and their complex mechanism of action gave a new direction to the treatment of metabolic diseases. The drugs presented below act on the incretin receptor, stimulating it and causing an effect that leads to weight loss.
Assessment of the occurrence of postural abnormalities in children aged 10-12 practicing various sports disciplines
Authors: Balińska Dagna , Ożóg Piotr , Weber-Rajek Magdalena , Radzimińska Agnieszka
Published: January 2025

Background: The increase in the prevalence of children with poor posture might be a result of decreased physical activity due to a sedentary lifestyle. Observing body posture is a crucial component of a physical examination. The examination can be performed objectively, for instance, with the aid of specific instruments, or subjectively, through visual inspection of the alignment of individual body parts in relation to one another. Objectives: The aim of our study was to assess the occurrence of postural abnormalities in children aged 10-12 who are physically active and practice various types of sports.Methods: The study group comprised 47 children aged 10–12 who were physically active and engaged in various sports activities. Participants have been visually examined based on a postural deficit chart derived from Kasperczyk’s criteria. Results: Our research showed that volleyball had the highest percentage of postural abnormalities, accounting for 33% of all postural irregularities in this group, while the lowest percentage was observed in children who practiced swimming, at 7%. Conclusion: Physical activity may have an impact on the occurrence of postural defects in early school children. Further research is needed to expand our findings to include the outcomes of objective posture assessment methods.
Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review
Authors: Ochońska Izabela , Jaglarz Karolina , Kuca Maciej , Cholewa Marcin , Jasiewicz Maria
Published: January 2025

Introduction and Objective. Every year, 20 million people are diagnosed with cancer, most of whom undergo chemotherapy at some stage of treatment. Chemotherapy is associated with various side effects, with hair loss being one of the most visible and socially stigmatizing. This study aimed to evaluate and summarize existing strategies for preventing chemotherapy-induced hair loss.
Review methods. Data for this paper were gathered using electronic databases like PubMed and Google Scholar, with a focus on papers from the last five years, particularly clinical trials, double-blind randomized studies, meta-analyses, and reviews.
State of Knowledge. Around 65% of chemotherapy patients experience hair loss. Currently, the FDA has approved one method for preventing chemotherapy-induced alopecia (CIA): scalp cooling. This technique induces localized vasoconstriction, reducing the penetration of chemotherapy drugs into hair follicles. Scalp cooling is generally well-tolerated. Other potential methods include scalp injections of autologous platelet-rich plasma, which contains growth factors and anti-inflammatory cytokines, and microneedling, an invasive procedure with uncertain effectiveness, especially as a standalone treatment, that aims to stimulate angiogenesis.
Conclusions. Effective, reliable methods for preventing chemotherapy-induced alopecia (CIA) are still lacking. A holistic approach to oncology care is needed to address the diverse needs of patients. Discovering new preventive methods would greatly improve patients' ability to cope with cancer treatment. However, most current approaches show only moderate efficacy or are still in clinical trials.
Branched-Chain Amino Acids (BCAAs): Revisiting Their Role in Sport and Health
Authors: Kajtel Aleksandra , Anna Skowronek  , Martyna Piekarska  , Katarzyna Dąbek  , Michał Ochwat  , Maria Sudoł  , Gabriela Mierzwa
Published: January 2025

Branched-chain amino acids (BCAAs), particularly leucine, are essential amino acids recognized for their significant roles in muscle protein synthesis, reducing muscle catabolism, and supporting metabolic health. This review explores the biochemistry, metabolism, and signaling pathways of BCAAs, emphasizing their potential therapeutic applications in conditions like sarcopenia, liver cirrhosis, and cachexia. BCAA metabolism primarily occurs in skeletal muscle and liver, with leucine activating key signaling pathways like mTORC1, promoting muscle growth and reducing protein breakdown. Clinical studies demonstrate the potential benefits of BCAA supplementation, particularly when combined with resistance exercise, in improving muscle quality and functional outcomes. However, effects on broader physical performance markers, insulin sensitivity, and metabolic profiles remain inconsistent. Safety data indicates leucine is well-tolerated at dosages up to 0.53 g/kg/day, but optimal dosages and timing require further study. Despite promising findings, the efficacy of BCAA supplementation is context-dependent, highlighting the need for longer trials and research targeting specific populations, including the elderly and those with chronic illnesses. Future research should focus on personalized protocols, the safety of long-term use, and combining BCAA supplementation with other interventions to maximize therapeutic potential. This article aims to revisit the biochemistry, therapeutic applications, and safety of BCAA supplementation, highlighting its potential in muscle preservation and metabolic health while identifying gaps for future research.
The long road to diagnosis, from gastroesophageal reflux disease, through Barrett's esophagus, to visceral hypersensitivity: a case report
Authors: Wirkijowska Małgorzata , Mędyk Jolanta , Patarocha Yauheniya , Rogulski Michał , Ślusarska Aleksandra , Błasiak Paulina , Mikołajec Patryk , Huk Ruslan , Bilecka Barbara , Wirkijowski Jakub
Published: January 2025

Background: Visceral hypersensitivity syndrome is a condition involving excessive perception of mechanical stimuli in the intestines. In patients suffering from this disorder, physiological bowel function causes pain and discomfort.

Case summary: The patient presented is a 26-year-old man with severe gastrointestinal symptoms that were difficult to manage, such as heartburn, pressure in the esophageal region, a sensation of a gullet in the throat, food retention, and frequent belching. The man had been experiencing these symptoms intermittently for four years, during which time he had been treated without success. By way of exclusion, a diagnosis of visceral hypersensitivity was made, and a low dose of amitriptyline was administered. Psychological therapy was also recommended. This treatment brought significant improvement and resulted in the resolution of his complaints.

Conclusions: Visceral hypersensitivity is strongly associated with psychosocial factors, which should be taken into account when treating patients with gastrointestinal disorders. Low doses of amitriptyline may be an effective treatment option.
La cuenta de Instagram de la marca Nike: un espacio estratégico para representar la diversidad.
Authors: Díaz-Bajo Rodríguez Javier , Martínez Borda Rut , Infante Pineda Sara
Published: January 2025

Las empresas se apoyan en la realidad social para instrumentalizar determinadas categorías socioculturales que fundamenten sus estrategias de comunicación de marca. A través del discurso
corporativo, las marcas buscan representar categorías culturales no estereotipadas de la realidad
globalizada de nuestro tiempo. El objetivo de esta investigación se fundamenta en inferir cómo la
marca Nike representa la diversidad sociocultural por medio de su estrategia de comunicación en
Instagram. La investigación toma como unidades de análisis los 82 vídeos que estaban presentes
en la cuenta de Instagram de la marca, desde febrero de 2020 hasta febrero de 2022. Los resultados revelan que la práctica discursiva de Nike ejerce como una práctica social en sí misma, ya que
moviliza sistemas específicos de pensamiento y conducta respecto a la diversidad de la sociedad globalizada. A través de los resultados obtenidos, este trabajo reafirma dos cuestiones: por
un lado, se evidencia el uso del discurso corporativo como un artefacto que legitima una visión
específica y globalizada de la diversidad cultural. Y por otro lado, este trabajo evidencia el uso
estratégico del aspecto físico de los deportistas en interacción con otras categorías culturales
como el género y la etnia, como símbolo de diversidad e inclusión.
Qué hace que una consulta sea “filosófica”? ¿Y qué la hace “buena”?.
Authors: Romizi Donata
Published: January 2025

In the realm of Philosophical Practice, there remains a lack of clarity
surrounding the essential characteristics that define a practice as “philosophical”.
This paper aims to establish seven minimal criteria that must be met by a
philosophical consultancy in order to be considered genuinely “philosophical”.
Additionally, it explores the question of how one can assess the quality of such a
philosophical consultancy. I provide a (non-exhaustive) answer from an
Aristotelian point of view, according to which goodness is a matter of balance. In
the context of philosophical consultancy, the consultant should find this balance
in two respects: first, between their concern for the topic and their concern for the
individual seeking counsel, and, secondly, between a hermeneutical and a critical
attitude in dialogue. Finally, I present a visual representation of my findings that
can serve as a tool for evaluating whether a consultancy is philosophical and
whether it is balanced
The Steady Decline of Club Culture in Dublin
Authors: O'Sullivan Caroline
Published: January 2025

The public health restrictions implemented by the Irish government due to Covid-19 resulted in one of the most extensive music industry lockdowns in Europe. Dublin, however, was already experiencing a large scale contraction of club culture. Prior to the pandemic, the physical spaces that dance music and club culture thrived in over the past 40 years had greatly diminished, many being demolished to make way for hotels and upmarket student accommodation. The onset of the pandemic meant this contraction intensified, and 2021 and 2022 saw the permanent closure of a number of high-profile and pivotal venues across the city. In discussing the effects of touristification and the pandemic on dedicated dancing spaces in Dublin, I contend that the underlying neoliberal government policies and outdated restrictive licensing laws have profoundly and detrimentally shaped the current clubbing landscape. The article explores the efforts of activist groups and grassroots campaigns, illustrating how the community has sought to reclaim space and mitigate the looming threat of decline. It specifically highlights campaigns for legislative reform and efforts to persuade policymakers that Dublin needs “No more Hotels” and “clubbing is culture”. The concluding section of the article assesses the outlook for Dublin's clubbing community and proposes avenues for future research.
“Being a DJ is My Form of Resistance”
Authors: Fuernkranz Magdalena
Published: January 2025

Vienna based queer-feminist networks, DJ collectives and event formats such as female:pressure, Dishes, Unsafe+Sounds and Hyperreality provide a platform for exploration of a radical, uncompromising queer-feminist approach in institutionalized spaces. The dance floor becomes a safer space for nonconformism, as well as a platform for time-limited utopias and subcultures in an institutional framework. As subcultural spaces, these collectives create events that form intensive, multi-layered and progressive line-ups and advocate for greater visibility and representation of marginalized groups on the dance floor.
This paper explores the potentials and limitations of queer-feminist DJs and DJ-collectives, music producers and club organizers that make use of social spaces such as the dance floor to create safer spaces for queer dance music communities. I suggest that queer-feminist DJing and its contexts are shaped by ideas of fourth-wave feminism, queer-feminist networks as well as by the use of social media to provide spaces for cultural production and political activism.
London Dubstep Culture in an Online Discord Community
Authors: Mouraviev Ivan
Published: January 2025

What happens when a music scene’s spaces of performing, socialising and dancing—including venues, radio stations, record stores and internet forums—are reconfigured online? When the scene in question gravitates around extreme sub-bass and the sound systems that reproduce it, how exactly does that scene take shape on the internet? This article addresses these questions by presenting a digital ethnography conducted with Real Heads, a dubstep-centric music community on the social media platform Discord established in 2019. The analysis focuses on a weekly broadcast of DJ sets by Real Heads hosted on the livestreaming site Twitch. I explore how this communal project, born out of COVID-19, reworks the space and sociality of early or so-called “real” dubstep (when the genre first emerged in London in 2001–6) through inherited musical practices and regimes of subcultural capital, particularly from pirate and internet radio. In doing so, the article wrestles with the tensions between the (im)material space of the internet and the community’s investment in dubstep’s sonics, heritage and performance practices. I argue that Real Heads represents a novel form of DJ culture that warrants critical attention, and ultimately show how the group’s online performances afford potent affective experience outside the physical space and visceral materiality of traditional sound system events: materiality that, at first glance, should be non-negotiable for “real” dubstep heads.
Noise as a Spectre in Dub Techno
Authors: Koçer Bahadırhan
Published: January 2025

This article explores dub techno's history and sonic characteristics, focusing on the role of noise as a critical stylistic element. It introduces hauntology as a hermeneutic framework to understand the intricate function of noise within the genre. This interpretive paradigm elevates noise beyond mere auditory embellishments, imbuing it with significant philosophical resonance. The article presents a chronological exegesis of dub techno's evolution and positions it as a conduit for philosophical contemplation. It highlights the enigmatic aesthetic essence of noise, urging readers to reevaluate its role in dub techno and electronic dance music. The objective is to offer insights and promote understanding, encouraging readers to engage with noise as a key component of philosophical and aesthetic discourse in dub techno.
Pemetaan Literasi Kesehatan Digital Siswa SMP di Kabupaten Buol
Authors: Muid Abdul , Arif Nursida , Marlinda Marlinda
Published: January 2025

Penelitian ini bertujuan untuk memetakan literasi kesehatan digital di kalangan siswa Sekolah Menengah Pertama (SMP) di Kabupaten Buol, Sulawesi Tengah. Sebanyak 185 siswa menjadi responden melalui survei dengan pendekatan kuantitatif. Penelitian ini mengukur lima indikator literasi kesehatan digital: keterampilan operasional, kemampuan mencari dan mengevaluasi informasi, kemampuan membuat konten, serta kemampuan melindungi privasi. Hasil penelitian menunjukkan bahwa 85,7% siswa memiliki keterampilan operasional yang rendah, namun mereka memiliki kemampuan yang baik dalam mengevaluasi informasi (100%) dan menambahkan konten (100%). Di sisi lain, pemahaman siswa tentang privasi digital bervariasi, dengan hanya sebagian kecil yang benar-benar memahami pentingnya melindungi privasi mereka. Meskipun siswa menunjukkan kemampuan yang baik dalam beberapa aspek literasi digital, kesadaran akan pentingnya privasi digital memerlukan perhatian lebih. Penelitian ini menekankan perlunya pendidikan yang lebih mendalam terkait literasi kesehatan digital, terutama dalam aspek perlindungan privasi dan keamanan data, agar siswa dapat memanfaatkan teknologi secara aman dan efektif. Hasil penelitian ini dapat dijadikan acuan untuk merumuskan kebijakan dan program yang mendukung peningkatan literasi digital di Kabupaten Buol.
Pengembangan E-Modul Proyek Penguatan Profil Pelajar Pancasila (P5) Tema Kearifan Lokal Topik Makanan Daerah Khas Yogyakarta Bagi Siswa Sekolah Dasar
Authors: Zahra Mar’atu , Indriani Fitri
Published: January 2025

Proyek Penguatan Profil Pelajar Pancasila (P5) adalah inisiatif pendidikan yang mengintegrasikan kurikulum merdeka untuk membentuk siswa yang kreatif dan adaptif. Penelitian ini bertujuan untuk mengembangkan E-modul proyek penguatan profil pelajar pancasila (P5) dengan tema kearifan lokal khususnya pada topik makanan khas Yogyakarta. Metode penelitian yang digunakan adalah research and development dengan model ADDIE (Analysis, Design, Development, Implementation, Evaluation). Uji coba produk dilakukan di SD N 1 Jetis dan SDIT Insan Utama Yogyakarta, dengan data dikumpulkan melalui wawancara dan angket. Teknik analisis data dilakukan secara kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa pengembangan E-modul P5 dimulai dari menganalisis kebutuhan guru dan siswa. Kemudian E-modul di desain menggunakan aplikasi canva sesuai flowchart. Pada tahap pengembangan ini, E-modul dinilai oleh para ahli. Setelah produk layak, dilakukan implementasi uji coba produk ke sekolah dasar. Tahap terakhir, peneliti melakukan evaluasi dan perbaikan E-modul agar lebih layak digunakan. Berdasarkan uji kelayakan oleh ahli media, ahli materi, ahli bahasa, ahli pembelajaran didapatkan nilai kelayakan 85,74 kategori baik dan layak. Sedangkan dari guru dan siswa mendapatkan nilai rata-rata respon 95,05 dengan kategori sangat baik dan sangat layak. Adapun E-modul ini mendapatkan respons positif dari guru karena dinilai dapat menarik minat belajar dan kreativitas siswa. Menurut siswa, E-modul ini dapat menambah semangat belajar dan menyenangkan sehingga memotivasi untuk belajar. Dengan demikian, dapat disimpulkan, E-modul P5 Tema Kearifan Lokal Materi Makanan Daerah Khas Yogyakarta layak digunakan untuk siswa sekolah dasar.
Faktor-Faktor yang Mempengaruhi Penerimaan Teknologi dalam Pembelajaran di SMA Bandar Lampung Menggunakan Model TAM di Era Disrupsi
Authors: Oktaria Sheren Dwi , Firdaus Rangga , Pangestu Deviyanti
Published: January 2025

This study aims to analyze the factors influencing technology acceptance in learning at high schools in Bandar Lampung based on the Technology Acceptance Model (TAM) in the era of disruption. The primary focus of this research is to explore the roles of Perceived Usefulness (PU), Perceived Ease of Use (PEOU), Attitude Toward Using (ATU), and Behavioral Intention to Use (BI) in shaping the attitudes and intentions of both teachers and students regarding the use of educational technology. A quantitative survey method was employed, utilizing questionnaires distributed to 200 respondents, consisting of teachers and students from various high schools in Bandar Lampung. Data were analyzed using multiple regression analysis to examine the relationships among the variables. The findings indicate that PU and PEOU significantly influence ATU, which in turn contributes to BI in utilizing technology for learning. This suggests that enhancing perceptions of the benefits and ease of use of technology can strengthen positive attitudes and intentions to adopt technology among students and teachers. The study recommends the development of technology training programs and improvements in digital infrastructure to support technology acceptance in educational settings.
Analisis Kemampuan Literasi Numerasi dalam Menyelesaikan Soal Cerita Matematika pada Siswa Kelas V SD Negeri 3 Tala
Authors: Razak Firdha , Musdalifah Musdalifah , Zaid Muhammad
Published: January 2025

Penelitian deskriptif kualitatif ini bertujuan untuk menganalisis dan mengetahui gambaran kemampuan literasi numerasi siswa dalam menyelesaikan soal cerita matematika. Indikator kemampuan literasi numerasi yaitu (1) mampu menggunakan simbol dan angka; (2) mampu menganalisis informasi soal; dan (3) mampu memprediksi dan mengambil keputusan hasil penyelesaian soal. Subjek penelitian berjumlah 3 subjek dan menggunakan instrumen lembar tes kemampuan literasi numerasi dan pedoman wawancara. Teknik analisis data terdiri dari tiga tahap yaitu reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa (1) siswa kemampuan literasi numerasi kategori tinggi dapat memenuhi ketiga indikator kemampuan literasi numerasi; (2) siswa kemampuan literasi numerasi kategori sedang hanya memenuhi indikator pertama dan indikator kedua, sedangkan indikator ketiga tidak terpenuhi; serta (3) siswa kemampuan literasi numerasi kategori rendah hanya memenuhi indikator kedua sedangkan indikator pertama dan ketiga tidak terpenuhi.
Implementasi pendidikan transformatif di sekolah dasar
Authors: A’yun Ummu Qurrota , Sulisworo Dwi , Maryani Ika
Published: January 2025

Penelitian ini bertujuan untuk mengeksplorasi implementasi pendidikan transformatif di Sekolah Dasar, dengan fokus pada peran kepemimpinan dalam mendorong inovasi dan pengembangan karakter siswa. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus, di mana data dikumpulkan melalui wawancara mendalam dengan kepala sekolah, guru, serta observasi langsung di lingkungan sekolah. Hasil penelitian menunjukkan bahwa kepemimpinan transformatif memainkan peran penting dalam menciptakan lingkungan belajar yang dinamis, kolaboratif, dan berorientasi pada pengembangan potensi siswa, baik dalam aspek akademik maupun karakter. Kepala sekolah yang menerapkan prinsip-prinsip kepemimpinan transformatif mampu menginspirasi guru untuk melakukan inovasi dalam proses pembelajaran. Implikasi penelitian ini menegaskan pentingnya model kepemimpinan yang progresif dalam meningkatkan kualitas pendidikan di tingkat dasar, serta memberikan wawasan bagi pengambil kebijakan dalam merumuskan strategi pendidikan yang berkelanjutan di era digital.
Development of a physiotherapist-led soft tissue trauma clinic: a quality improvement pilot study
Authors: Kelly Debbie , Read Andrew , Jones Robert , Jones Ian , Linnell Lynsey , Fielder Daniel , Bokota Heather
Published: January 2025

Background/Aims

Musculoskeletal disorders account for half of all attendances in emergency departments, with large volumes of patients being referred to fracture clinics. This project implemented a 3-month pilot of an advanced practice physiotherapist-led soft tissue trauma clinic, to see 80% of all patients referred from the virtual fracture clinic for knee and shoulder soft tissue trauma.

Methods

A quality improvement approach was used to set up the clinics and monitor changes made throughout the process using plan-do-study-act cycles. Data were collected from the pilot clinic on outcomes such as onwards referrals, imaging requests and costs. Data from a previous service evaluation of the fracture clinic were used for comparison. A patient satisfaction questionnaire, including the VSQ-9, was distributed to patients at the pilot clinic and fracture clinic, with mean scores compared using descriptive statistics.

Results

During the 3-month pilot, 89.4% (101/113) of patients with knee or shoulder soft tissue injuries were referred to the pilot clinic, of whom only 13.8% required a consultant review. A higher proportion of patients at the soft tissue trauma clinic could be discharged after their first appointment compared to before the pilot (64.3% vs 19.6%) and patient satisfaction scores remained high.

Conclusions

This pilot clinic showed the benefits of standardising patient care pathways. It has since been extended for a further 1 year and expanded to include foot and ankle soft tissue trauma.
Artificial intelligence in emergency medicine
Authors: Matthews Jonathan
Published: January 2025

Artificial intelligence attracts controversy, but it is impossible to ignore its potential to transform healthcare. This article examines some of the established and potential applications of artificial intelligence in emergency care settings, noting where clinicians may be able to apply this technology to their departmental practice.
Starting out write
Authors: Kirby Gemma
Published: January 2025

Gemma Kirby, associate lecturer at University College Birmingham, shares tips for celebrating and promoting early handwriting skills in time for National Handwriting Day at the end of January.
Clinical Efficacy of Pidotimod-Assisted Erythromycin in Treating Lobar Pneumonia in Children Over 3 Years Old
Authors: Ke Jie , Tu Xiqing
Published: January 2025

Aims/Background Lobar pneumonia is an acute inflammation with increasing incidence globally. Delayed treatment can lead to severe complications, posing life-threatening risks. Thus, it is crucial to determine effective treatment methods to improve the prognosis of children with lobar pneumonia. Therefore, this study aimed to assess the clinical efficacy of pidotimod-assisted erythromycin in treating lobar pneumonia in children over 3 years old.

Methods This study included 108 children with lobar pneumonia admitted to the Huoqiu First People's Hospital, China, between March 2021 and March 2024. However, 6 children (4 cases with missing clinical data, 1 with autoimmune disease, and 1 with asthma) who did not meet the predetermined inclusion criteria were excluded. Based on the treatment methods, the children were divided into a control group (n = 52, children receiving erythromycin treatment) and an observation group (n = 50, children receiving pidotimod-assisted erythromycin treatment). Furthermore, the clinical efficacy, clinical signs, resolution time of symptoms, cellular immune function, and incidence of adverse reactions were retrospectively evaluated.

Results The control group exhibited significantly lower treatment efficiency than the observation group (80.77% vs 94.00%; p < 0.05). Furthermore, the observation group showed better alleviating fever, cough, tachypnea, and pulmonary moist rales (p < 0.001). The CD3+, CD4+, and CD4+/CD8+ levels were comparable in both groups before treatment (p > 0.05). However, 7 days after treatment, the CD3+, CD4+, and CD4+/CD8+ levels increased significantly in the observation group compared to the control group (p < 0.001). Additionally, there was no significant difference in the incidence of adverse reactions in both groups (p > 0.05).

Conclusion Pidotimod-assisted erythromycin treatment can significantly improve the treatment efficiency in children with lobar pneumonia, improving clinical signs and symptoms and enhancing the cellular immune function without increasing the risk of adverse drug reactions.
John Logie Baird: The Founding Father of Television
Authors: Smith Nick
Published: January 2025

Scottish engineer and inventor John Logie Baird has gone down in history as a pioneer of television, who in 1926 became the first to demonstrate the televising of moving objects.
A Dual-polarized Reflectarray Antenna for High-speed Ka-band Satellite Communications
Authors: Gülseren Ahmet Hulusi , Yılmaz Selda , Alparslan Aytaç , Tokan Nurhan Türker
Published: January 2025

A small-sized reflectarray antenna array with compact production specifications is designed and fabricated for high-speed Ka-band communication systems. In the design phase, firstly, the reflection characteristics of unit cells used in the reflective surface are obtained by the full wave computational analysis tool, CST Microwave Studio. Secondly, an aperture efficiency analysis is carried out to determine the physical size of the reflectarray and the distances between the feeding antenna and the individual unit cells. Then, the entire reflectarray antenna is analyzed by array theory to obtain geometrical dimensions to be used in the fabrication phase. These results are verified by CST Microwave Studio and similar fabrication guidelines are obtained for both TE and TM polarizations. In the fabrication phase, the carefully tailored design parameters of the unit cells are used to build the antenna and measure important parameters such as radiation patterns, gain, cross polarization levels and S11 parameters, which agree with the results obtained in the design phase. The proposed reflectarray antenna makes it possible to support dual-polarized multi-beams in the range 18-20 GHz with stable gain behavior, which makes it possible to use it in high speed 5G satellite communication systems.
Bandwidth and Gain Improvement of a Circularly Polarized Slot Antenna Using Nonuniform Metasurface
Authors: Chen Qiang , Yang Jun , He Changhui , Hong Liang , Yan Tianci , Yu Fangli , Zhang Di , Huang Min
Published: January 2025

This paper presents a novel design of a circularly polarized antenna based on a nonuniform metasurface (NMS). The original antenna comprises a uniform metasurface (UMS) layer and a slot antenna below. In order to achieve circularly polarized (CP) radiation, an oblique slot is etched on the center patch, and the size ratio between the center patch and the surrounding patches is adjusted to create the NMS. To further enhance the CP properties, an improved NMS (INMS) is proposed, consisting of four units with corners removed, building upon the original NMS design. Simulation results demonstrate that the proposed antenna design offers an S11 bandwidth ranging from 4.39 to 7.21 GHz, with a 3 dB axial ratio (AR) bandwidth spanning from 5.43 GHz to 6.76 GHz. Compared to the original UMS-based antenna, the INMS design shows an average gain increase of 1.21 dB, with a peak gain of 9.49 dBic. Furthermore, utilizing characteristic mode analysis (CMA), this paper explores the modal behaviors when applying the NMS to the antenna. The results indicate that this configuration excites two orthogonal modes, leading to CP radiation and the emergence of an additional AR minimum point. These factors contribute to the broader bandwidth observed in the proposed antenna design. The outstanding radiation performance of the proposed antenna design makes it suitable for various applications, including military and civilian communication, as well as point-to-point links.