bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of rheological and image properties of styrene‐butadiene‐styrene and ethylene‐vinyl acetate polymer modified bitumens
Authors: Topal Ali , Yilmaz Mehmet , Kok Baha Vural , Kuloglu Necati , Sengoz Burak
Published: July 2011

This article presents a laboratory evaluation of conventional, fundamental, rheological, and morphological characteristics of styrene‐butadiene‐styrene (SBS) and ethylene vinyl acetate (EVA) polymer modified bitumens. Polymer modified bitumen (PMB) samples have been produced by mixing a 50/70 penetration grade unmodified (base) bitumen with SBS and EVA copolymer at different polymer contents. The fundamental viscoelastic properties of the PMBs were determined using dynamic (oscillatory) mechanical analysis and presented in the form of temperature and frequency‐dependent rheological parameters. The morphology of the samples as well as the percent area distribution of polymers throughout the base bitumen have been characterized and determined by means of fluorescent light optic microscopy and Qwin Plus image analysis software, respectively. The results indicated that polymer modification improved the conventional and rheological properties of the base bitumen. It was also concluded that the temperature and frequency had a significant effect on complex modulus of PMBs. The behavior of EVA and SBS PMBs had exhibited quite difference at 50°C. Moreover, it was found out that at low polymer contents, the samples revealed the existence of dispersed polymer particles in a continuous bitumen phase, whereas at high polymer contents a continuous polymer phase has been observed. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Structure and properties development in poly(phenylene sulfide) fibers, part I: Effect of material and melt spinning process variables
Authors: Gulgunje Prabhakar , Bhat Gajanan , Spruiell Joseph
Published: July 2011

The detailed research study of manufacturing PPS fibers using melt spinning and further enhancement of tensile properties by drawing and annealing experiments, a study lacking as of today in open scientific literature, was the focus of this research. This article discusses the effect of polymer molecular weight (MW) and melt spinning process variables on the structure and properties development in melt spun fibers manufactured from proprietary Fortron® linear PPS resins. Structure‐properties relationship was studied using several characterization tools like tensile testing, differential scanning calorimetry, polarized light optical microscopy, and wide‐angle x‐ray scattering. Changes in dynamic mechanical behavior of as‐spun fibers manufactured from resins of varying MW and different melt spinning take‐up speeds were also studied. The study showed that by a combination of higher MW of the polymer and spinning at higher take‐up speeds, tensile properties of as‐spun PPS fibers can be improved. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Crosslinking benzotriazolylimides and polymeric materials on base of them
Authors: Farion Ivan A. , Mognonov Dmitrii M. , Il'ina Olga V. , Bal'zhinov Sergey A.
Published: July 2011

A new kind of crosslinking oligobenzotriazolylimides with terminal maleimide groups has been synthesized via an interaction of an excess of bismaleimides with 5,5′‐bisbenzotriazoles in melt. Conditions of obtaining these oligomers were optimized via the syntheses of model compounds. Oligomers, according to dynamic thermogravimetric analysis (DTGA), fuse at 135–160°C, crosslink at 175–250°C, and possess the high thermal stability in air up to 410°C. Using these oligomers as thermosetting binders or crosslinking agents, tough laminate plastics reinforced by a glass‐fiber cloth as well as crosslinked films on base of a linear polybenzimidazole (PBI) matrix were obtained. The plastics and the crosslinked films possess high mechanical characteristics. It has been proved that the crosslinked films on base of the PBI matrix are perspective precursors to design the phosphoric acid electrolyte membranes for the medium temperature fuel cells. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Coexpression of chemokine receptors CCR5, CXCR3, and CCR4 and ligands for P‐ and E‐selectin on T lymphocytes of patients with juvenile idiopathic arthritis
Authors: Issekutz Andrew C. , Quinn Patrick J. , Lang Bianca , Ramsey Suzanne , Huber Adam M. , Rowter Derek , Karkada Mohan , Issekutz Thomas B.
Published: July 2011

Objective

To investigate P‐ and E‐selectin ligand coexpression with chemokine receptors (CKRs) on T cells in the synovial fluid (SF) and blood of children with juvenile idiopathic arthritis (JIA).

Methods

Sixteen patients with polyarticular or persistent oligoarticular JIA (ages 5.3–15.1 years) were studied. SF and venous blood were collected, and immunostaining for the expression of CCR4, CCR5, CXCR3, and P‐ or E‐selectin ligands was performed.

Results

Compared to blood, SF was greatly enriched for CD4+ T cells bearing CCR5, CCR4, CXCR3, and both P‐ and E‐selectin ligand. Twenty‐five percent of the CD4+ T cells in SF expressed both CCR5 and CCR4, some also coexpressing CXCR3. Such cells were rare in blood. Half of the few CCR5+ T cells in blood coexpressed P‐ or E‐selectin ligand, a phenotype that was enriched up to 50‐fold in SF. A minority of CCR4+ and CXCR3+ cells in blood (∼25%) coexpressed selectin ligand; these were enriched 4–8‐fold in SF. Most CCR4‐expressing CD4+ T cells expressed both E‐selectin ligand and cutaneous lymphocyte antigen.

Conclusion

CCR4‐, CCR5‐, CXCR3‐, and selectin ligand–expressing CD4+ T cells preferentially accumulate in the joints of children with JIA. The marked enrichment of CCR5+ T cells coexpressing P‐selectin and/or E‐selectin ligand in CD4+ SF T cells suggests that the few such cells in blood selectively migrate to inflamed joints via endothelial P‐ and E‐selectin– and CCR5‐activating chemokines. The predominance of CCR4‐expressing CD4+ T cells coexpressing E‐selectin ligand suggests that such cells migrate not only to areas of cutaneous inflammation, as previously reported, but also to the joints in JIA. Combined targeting of CCR5‐ and E‐selectin–dependent mechanisms may be a relevant treatment strategy.
Autoimmunity and inflammation are independent of class II transactivator type PIV–dependent class II major histocompatibility complex expression in peripheral tissues during collagen‐induced arthritis
Authors: Waldburger Jean‐Marc , Palmer Gaby , Seemayer Christian , Lamacchia Celine , Finckh Axel , Christofilopoulos Panayiotis , Baeten Dominique , Reith Walter , Gabay Cem
Published: July 2011

Objective

To determine the regulation of class II major histocompatibility complex (MHC) expression in fibroblast‐like synoviocytes (FLS) in order to investigate their role as nonprofessional antigen‐presenting cells in collagen‐induced arthritis (CIA).

Methods

Expression of class II MHC, class II MHC transactivator (CIITA), and Ciita isoforms PI, PIII, and PIV was examined by real‐time quantitative polymerase chain reaction, immunohistochemistry, and flow cytometry in human synovial tissues, arthritic mouse joints, and human and murine FLS. CIA was induced in mice in which isoform PIV of Ciita was knocked out (PIV−/−), in PIV−/− mice transgenic for CIITA in the thymus (K14 CIITA), and in their control littermates.

Results

HLA–DRA, total CIITA, and CIITA PIII messenger RNA levels were significantly increased in synovial tissue samples from patients with rheumatoid arthritis compared with the levels in tissue from patients with osteoarthritis. Human FLS expressed surface class II MHC via CIITA PIII and PIV, while class II MHC expression in murine FLS was entirely mediated by PIV. Mice with a targeted deletion of CIITA PIV lack CD4+ T cells and were protected against CIA. The expression of CIITA was restored in the thymus of PIV−/− K14 CIITA–transgenic mice, which had a normal CD4+ T cell repertoire and normal surface levels of class II MHC on professional antigen‐presenting cells, but did not induce class II MHC on FLS. Synovial inflammation and immune responses against type II collagen were similar in PIV−/− K14 CIITA–transgenic mice and control mice with CIA, but bone erosion was significantly reduced in the absence of PIV.

Conclusion

Overexpression of class II MHC is tightly correlated with CIITA expression in arthritic synovium and in FLS. Selective targeting of Ciita PIV in peripheral tissues abrogates class II MHC expression by murine FLS but does not protect against inflammation and autoimmune responses in CIA.
Genetic variants in the HLA–DRB1 gene are associated with Kashin‐Beck disease in the Tibetan population
Authors: Shi Yi , Lu Fang , Liu Xin , Wang Yao , Huang Lulin , Liu Xiaoqi , Long Wubin , Lv Bo , Zhang Kun , Ma Shi , Lin He , Cheng Jing , Zhou Bin , Hu Mei , Deng Jiayun , Zhu Jianxin , Hao Peng , Yang Xiao , Zeng Mingcai , Wang Xiaoquan , Shen Sikui , Yang Zhenglin
Published: July 2011

Objective

To investigate the association between variants in the HLA–DRB1 gene and Kashin‐Beck disease (KBD), as well as associations of selenium and iodine deficiencies with KBD in a Tibetan population.

Methods

Fourteen single‐nucleotide polymorphisms (SNPs) were genotyped around the HLA–DRB1 gene, and HLA–DRB1 allele genotyping was performed in a discovery cohort, composed of 605 patients with KBD and 393 control subjects, and/or a replication cohort, composed of 290 patients with KBD and 295 controls. Plasma concentrations of selenium and iodine were measured and compared by t‐test in 299 patients with KBD and 280 controls from the same villages.

Results

Four SNPs (rs6457617, rs6457620, rs9275295, and rs7745040) in the HLA–DRB1 gene locus were significantly associated with KBD in both the discovery cohort and replication cohort (combined cohort odds ratios [ORs] 1.307–1.402, P = 0.0039–0.0006). The protective haplotype GTCC and the risk haplotype ACGT, each generated by the 4 SNPs, showed a significant association with KBD (for GTCC, OR 0.77, P = 0.0031; for ACGT, OR 1.40, P = 0.0014). HLA–DRB1 allele genotyping revealed that the frequencies of HLA–DRB1*08 and *11 were significantly different between patients with KBD and controls (for HLA–DRB1*08, OR 0.731, P = 0.00564; for HLA–DRB1*11, OR 0.489, P = 0.000395). Moreover, plasma concentrations of selenium and iodine were significantly different between patients with KBD and controls from the same villages (P = 0.0013 and P = 1.84 × 10−12, respectively).

Conclusion

These findings, obtained in plasma samples from Tibetan patients with KBD and healthy control subjects from the same regions, confirm the role of selenium and iodine deficiencies in the development of KBD. Moreover, genetic variants in the HLA–DRB1 gene significantly increase the susceptibility to KBD in this population.
On the determination of the solutions and maximum admissible power of the load flow equation via LMIS
Authors: Chesi G. , Hung Y. S.
Published: July 2011

It is well‐known that the load flow equation plays a key role in power systems. This paper investigates the load flow equation addressing two fundamental problems, namely the determination of the solutions of this equation in a given region of interest, and the computation of the maximum admissible power for which this equation has a solution in such a region. For the first problem, it is shown that the sought solutions can be computed by solving an eigenvalue problem (EVP), i.e. a convex optimization problem with linear matrix inequality (LMI) constraints, and by looking for vectors with special structure into a linear subspace. For the second problem, it is shown that an upper bound of the sought maximum admissible power can be found by solving another EVP, moreover a sufficient and necessary condition for establishing the tightness of the found upper bound is provided. The proposed methodology is illustrated by some numerical examples.

Copyright © 2011 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
Are the Ro RNP‐associated Y RNAs concealing microRNAs? Y RNA‐derived miRNAs may be involved in autoimmunity
Authors: Verhagen Anja P. M. , Pruijn Ger J. M.
Published: July 2011

Here we discuss the hypothesis that the RNA components of the Ro ribonucleoproteins (RNPs), the Y RNAs, can be processed into microRNAs (miRNAs). Although Ro RNPs, whose main protein components Ro60 and La are targeted by the immune system in several autoimmune diseases, were discovered many years ago, their function is still poorly understood. Indeed, recent data show that miRNA‐sized small RNAs can be generated from Y RNAs. This hypothesis leads also to a model in which Ro60 acts as a modulator in the Y RNA‐derived miRNA biogenesis pathway. The implications of these Y RNA‐derived miRNAs, which may be specifically produced under pathological circumstances such as in autoimmunity or during viral infections, for the enigmatic function of Ro RNPs are discussed.
A highly selective fluorescent probe for pyrophosphate detection in aqueous solutions
Authors: Ganjali M. R. , Hosseini M. , Aboufazeli F. , Faridbod F. , Goldooz H. , Badiei A. R.
Published: July 2011

A novel and simple fluorescence enhancement method is introduced for selective pyrophosphate (PPi) sensing in an aqueous solution. The method is based on a 1:1 metal complex formation between tris(8‐hydroxyquinoline‐5‐sulphonate) thulium(III) [Tm(QS)3] and PPi ion. The linear response covers a concentration range of 1.6 × 10−7–1.0 × 10−5 mol/L PPi and the detection limit is 2.3 × 10−8 mol/L. The association constant of Tm(QS)3–PPi complex was calculated as 2.6 × 105 mol/L. Tm(QS)3 shows a selective and sensitive fluorescence enhancement toward PPi ion in comparion with I3−, NO3−, CN−, CO32−, Br−, Cl−, F−, H2PO4− and SO42−, which is attributed to higher stability of the inorganic complex between pyrophosphate ion and Tm(QS)3. Copyright © 2011 John Wiley & Sons, Ltd.
Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line
Authors: Polo M. P. , Crespo R. , de Bravo M. G.
Published: July 2011

Simvastatin is a competitive inhibitor of 3‐hydroxymethylglutaryl coenzyme A reductase activity, whereas geraniol is a monoterpene with multiple pharmacologic effects on mevalonate metabolism. Both of them inhibit growth and proliferation of many cell lines. The present study was designed to determine the action of geraniol, in combination with simvastatin, by assessing their effects in vitro on human hepatocarcinoma cell line (Hep G2). The treatment of Hep G2 cells with concentrations of simvastatin or geraniol that did not inhibit cell proliferation (5 µmol·l‐1 of simvastatin and 50 µmol·l‐1 of geraniol) resulted in a significant inhibition of cell proliferation. We also examined the effect of simvastatin, geraniol and the combination of both on the biosynthesis of lipids from [14C]‐acetate. Our results demonstrate that the combination of simvastatin and geraniol synergistically inhibited cholesterol biosynthesis and proliferation of Hep G2 cell line, contributing to a better understanding of the action of a component of essential oils targeting a complex metabolic pathway, which would improve the use of drugs or their combination in the fight against cancer and/or cardiovascular diseases. Copyright © 2011 John Wiley & Sons, Ltd.
Binding Energetics of Ferredoxin‐NADP+ Reductase with Ferredoxin and Its Relation to Function
Authors: Lee Young‐Ho , Ikegami Takahisa , Standley Daron M. , Sakurai Kazumasa , Hase Toshiharu , Goto Yuji
Published: July 2011

To obtain insight into the motional features of proteins for enzymatic function, we studied binding reactions between ferredoxin‐NADP+ reductase (FNR) and ferredoxin (Fd) using isothermal titration calorimetry and NMR‐based magnetic relaxation and hydrogen/deuterium exchange (HDex). Fd–FNR binding was accompanied by endothermic reactions and driven by the entropy gain. Component‐wise analysis of the net entropy change revealed that increases in the conformational entropy of the Fd–FNR complex contributed largely to stabilizing the complex. Intriguingly, analyses of magnetic relaxation and HDex rates with X‐ray B factor implied that Fd binding led to both structural stiffening and softening of FNR. Enhanced FNR backbone fluctuations suggest favorable contributions to the net conformational entropy. Fd‐bound FNR further showed that relatively large‐scale motions of the C terminus, a gatekeeper for interactions of NADP+(H), were quenched in the closed form, thereby facilitating exit of NADP+(H). This can provide a first dynamic structure‐based explanation for the negative cooperativity between Fd and NADP+(H) via FNR.
ChemInform Abstract: Two Dodecahydro‐closo‐dodecaborates with Lone‐Pair Cations of the 6th Period in Comparison: Tl2[B12H12] and Pb(H2O)3 [B12H12]·3H2O.
Authors: Tiritiris Ioannis , Van Nguyen‐Duc , Schleid Thomas
Published: July 2011

Compounds (III) and (VI) are characterized by single crystal XRD.
ChemInform Abstract: Enhancement of the Thermoelectric Figure‐of‐Merit in a Wide Temperature Range in In4Se3‐xCl0.03 Bulk Crystals.
Authors: Rhyee Jong‐Soo , Ahn Kyunghan , Lee Kyu Hyoung , Ji Hyo Seok , Shim Ji‐Hoon
Published: July 2011

Bulk crystal ingots of In4Se3‐xCl0.03 (x = 0.33 and 0.68) are prepared by the Bridgman method from stoichiometric amounts of In, Se, and InCl3 (quartz tube, 590 °C, 12 h).
ChemInform Abstract: Control of the Electronic Properties and Resistive Switching in the New Series of Mott Insulators GaTa4Se8‐yTey (0 ≤ y ≤ 6.5).
Authors: Guiot V. , Janod E. , Corraze B. , Cario L.
Published: July 2011

Single crystals of GaTa4Se8, GaTa4Se5.24Te2.76, GaTa4Se4Te4, GaTa4Se2Te6, and GaTa4Se1.47Te6.53 are prepared from stoichiometric mixtures of the elements (1000 °C, 160 h).
ChemInform Abstract: Growth and Characterization of a New Langasite‐Type Single Crystal Sr3NbAl1.5Ga1.5Si2O14 .
Authors: Zeng Yiming , Zheng Yanqing , Kong Haikuan , Xin Jun , Chen Hui , Tu Xiaoniu , Gao Pan , Shi Erwei
Published: July 2011

Single crystals of the title compound are grown by the Czochralski method from polycrystalline materials obtained from SrCO3, Ta2O5, Al2O3, Ga2O3, and SiO2 (Ir crucible, N2/1 vol.% O2).
ChemInform Abstract: Temperature‐Induced Enhancement of Catalytic Performance in Selective Hydrogen Generation from Hydrous Hydrazine with Ni‐Based Nanocatalysts for Chemical Hydrogen Storage.
Authors: Singh Sanjay Kumar , Lu Zhang‐Hui , Xu Qiang
Published: July 2011

Ni nanoparticles, which are inactive for the decomposition of hydrazine in aqueous solution at room temperature, show drastically enhanced catalytic activity at 323 K with an H2 selectivity of 33%.
ChemInform Abstract: Syntheses, Crystal Structures, and Thermal Behaviors of Two New Metallo‐Organically Templated Pentaborates.
Authors: Yang Yang , Wang Yu , Zhu Jiang , Liu Rui‐Bin , Xu Jun , Meng Chang‐Gong
Published: July 2011

Two new cadmium borates (III) and (IV) are characterized by single crystal XRD and IR spectroscopy.
ChemInform Abstract: Facile Temperature‐Controlled Synthesis of Hexagonal Zn2GeO4 Nanorods with Different Aspect Ratios Toward Improved Photocatalytic Activity for Overall Water Splitting and Photoreduction of CO2.
Authors: Yan Shicheng , Wan Lijuan , Li Zhaosheng , Zou Zhigang
Published: July 2011

Single‐crystalline hexagonal prism of Zn2GeO4 nanorods are synthesized from aqueous solutions of Na2GeO3 and Zn(OAc)2 (oil bath, 40—100 °C, 15—3 h).
ChemInform Abstract: Synthesis, Structure, and Photochemistry of an Organic Heptamolybdate‐Monomolybdate.
Authors: Wutkowski Adam , Srinivasan Bikshandarkoil R. , Naik Ashish R. , Schuett Christian , Naether Christian , Bensch Wolfgang
Published: July 2011

Irradiation of compound (II) with sunlight leads to the formation of the oxido‐bridged diheptamolybdate (III).
ChemInform Abstract: Synthesis of ThCr2Si2‐Type Arsenides from Bi Flux.
Authors: Thompson Corey M. , Kovnir Kirill , Eveland Stephanie , Herring Mitchell J. , Shatruk Michael
Published: July 2011

LaCo2As2 single crystals of good quality are prepared from a 1:2:2 mixture of La, Co, and As in a Bi flux (evacuated quartz tube, 1173 K, 10 d).
ChemInform Abstract: A RuII—N‐Heterocyclic Carbene (NHC) Complex from Metal—Metal Singly Bonded Diruthenium(I) Precursor: Synthesis, Structure and Catalytic Evaluation.
Authors: Sinha Arup , Daw Prosenjit , Rahaman S. M. Wahidur , Saha Biswajit , Bera Jitendra K.
Published: July 2011

The title complex exhibits good activities in the transfer hydrogenation of ketones to alcohols, as carbene‐transfer catalyst and for carbene insertion into N—H and O—H bonds of amines and alcohols.
ChemInform Abstract: Base‐Mediated Intermolecular sp2 C—H Bond Arylation via Benzyne Intermediates.
Authors: Truong Thanh , Daugulis Olafs
Published: July 2011

A transition‐metal‐free method for arylation of heterocycles and arenes by aryl chlorides and fluorides is developed.
ChemInform Abstract: Synthesis of New Chiral Ligands Based on Thiophene Derivatives for Use in Catalytic Asymmetric Oxidation of Sulfides.
Authors: Jeong Yong‐Chul , Ahn Dae‐Jun , Lee Woo‐Sun , Lee Seung‐Han , Ahn Kwang‐Hyun
Published: July 2011

Vanadium complexes of new Schiff base ligands prepared from thiophene derivatives efficiently catalyze the asymmetric oxidation of sulfides by hydrogen peroxide.
ChemInform Abstract: Facile Cu(OTf)2‐Catalyzed Preparation of 9‐Tosylaminofluorene Derivatives from o‐Arylated N‐Tosylbenzaldimines.
Authors: Yu Xufen , Lu Xiyan
Published: July 2011

In most cases, the expected products are formed in an easy manner.
ChemInform Abstract: 2‐[1,3‐Bis(ethoxycarbonyl)azulen‐6‐yl]ethynyltriphenylphosphonium Bromide.
Authors: Morita Noboru , Moriyama Shiro , Toyota Kozo , Watanabe Masataka , Kikuchi Shigeru , Ito Shunji , Fujimori Kunihide
Published: July 2011

Title compound (IV) is prepared from ethynylazulene (I) in two steps and good overall yield.
ChemInform Abstract: Facile AlCl3‐Promoted Catalytic Beckmann Rearrangement of Ketoximes.
Authors: Liu Li‐Feng , Liu Hua , Pi Hong‐Jun , Yang Shuo , Yao Min , Du Wenting , Deng Wei‐Ping
Published: July 2011

A highly efficient, inexpensive, and commercially available catalyst for the title rearrangement is found.
ChemInform Abstract: Epoxidation of Alkenes and Oxidation of Alcohols with Hydrogen Peroxide Catalyzed by a Manganese(V) Nitrido Complex.
Authors: Kwong Hoi‐Ki , Lo Po‐Kam , Lau Kai‐Chung , Lau Tai‐Chu
Published: July 2011

The first examples of efficient catalytic oxidation of alkenes and alcohols using H2O2 as oxidant and a manganese (V) nitrido complex as catalyst are given.
ChemInform Abstract: An Efficient Hydrogenation of Various Alkenes Using Scrap Automobile Catalyst.
Authors: Zengin Mustafa , Genc Hayriye , Demirci Tuna , Arslan Mustafa , Kucukislamoglu Mustafa
Published: July 2011

A used automobile catalytic converter is taken from a Fiat Siena.
ChemInform Abstract: 2‐Azido‐1,3‐dimethylimidazolinium Salts: Efficient Diazo‐Transfer Reagents for 1,3‐Dicarbonyl Compounds.
Authors: Kitamura Mitsuru , Tashiro Norifumi , Miyagawa Satoshi , Okauchi Tasuo
Published: July 2011

Both reagents (Ia) and (Ib) are found to be suitable for the diazotation reaction.
ChemInform Abstract: Ring‐Rearrangement Metathesis of 1‐Substituted 7‐Azanorbornenes as an Entry to 1‐Azaspiro[4.5]decane Systems.
Authors: Carreras Javier , Avenoza Alberto , Busto Jesus H. , Peregrina Jesus M.
Published: July 2011

In the presence of Ru catalysts, the azanorbornenes (I) and (Xa) undergo efficient ring‐opening/ ring‐closure metathesis to afford azaspirocyclic compounds.
ChemInform Abstract: Manganese(III) Porphyrin Covalently Bound to Sol—Gel Derived Silica (Mn(III) Porphyrinosilica): A Reusable and Green Heterogeneous Photocatalyst for Oxidative Decarboxylation of α‐Arylacetic Acids with H2O2.
Authors: Farhadi Saeid , Zabardasti Abedien , Rahmati Mohammad Hosien
Published: July 2011

The activity of the heterogeneous title photocatalyst in the oxidative decarboxylation of α‐arylacetic acids (I) is significantly higher than that of the corresponding homogeneous system.
ChemInform Abstract: Bicyclic Guanidinate Compounds of Magnesium and Their Activity as Pre‐Catalysts in the Tishchenko Reaction.
Authors: Day Benjamin M. , Mansfield Natalie E. , Coles Martyn P. , Hitchcock Peter B.
Published: July 2011

A novel magnesium guanidinate complex is prepared and used as a catalyst in the Tishchenko reaction of aldehydes (I).
ChemInform Abstract: An Effective Method to Prepare Imines from Aldehyde, Bromide/Epoxide, and Aqueous Ammonia.
Authors: Huang Jing‐Mei , Zhang Jue‐Fei , Dong Yi , Gong Wen
Published: July 2011

It provides a simple approach to a wide range of imines.
ChemInform Abstract: Synthesis of syn and anti 1,4‐Diols by Copper‐Catalyzed Boration of Allylic Epoxides.
Authors: Tortosa Mariola
Published: July 2011

The regio‐ and diastereoselective Cu(I)‐catalyzed boration of allylic epoxides offers a new approach for the diastereoselective synthesis of anti and syn 1,4‐diols.
ChemInform Abstract: Pyrrole Macrocyclic Ligands for Cu‐Catalyzed Asymmetric Henry Reactions.
Authors: Gualandi Andrea , Cerisoli Lucia , Stoeckli‐Evans Helen , Savoia Diego
Published: July 2011

The new macrocyclic pyrrole (MCP) efficiently promotes the enantioselective coupling of a wide range of aldehydes with nitromethane.
ChemInform Abstract: Synthesis of Propylene Glycol Methyl Ether Catalyzed by MCM‐41.
Authors: Liang Shuguang , Zhou Yinxi , Liu Huizhen , Jiang Tao , Han Buxing
Published: July 2011

MCM‐41, prepared using cetyltrimethylammonium bromide as the template, is shown to be an effective and reusable catalyst for the regioselective ring opening of propylene oxide (I) yielding 1‐methoxy‐2‐propanol (III) as the predominant product.
ChemInform Abstract: Friedel—Crafts Reactions of 2,2‐Difluorocyclopropanecarbonyl Chloride: Unexpected Ring‐Opening Chemistry.
Authors: Dolbier William R. Jr. , Cornett Eric , Martinez Henry , Xu Wei
Published: July 2011

AlCl3‐mediated treatment of the title chloride (I) with arenes results in formation of aryl cyclopropyl ketones and/or unexpected ring‐opening products of type (II).
ChemInform Abstract: Grob Fragmentation of Norbornyl α‐Diketones: A Route to α‐Ketoenols and Aromatic Compounds.
Authors: Khan Faiz Ahmed , Rao Ch. Nageswara
Published: July 2011

Norbornyl α‐diketones undergo facile Grob fragmentation to afford α‐ketoenols such as (II).
ChemInform Abstract: Aromatic Iodination Using N‐Iodosaccharin in Room Temperature Ionic Liquids.
Authors: Bailey Lindsey , Handy Scott T.
Published: July 2011

The process can be applied to various arenes including those which are only modestly activated.
ChemInform Abstract: Diaryl Ether Containing N‐Hydroxycarbamates from Nitroso Cycloadducts.
Authors: Bolger Joshua , Miller Marvin
Published: July 2011

Regioselective copper‐catalyzed ring‐opening alkylation of cycloadducts such as (I) with chloride (II) is optimized and applied to the synthesis of the phenolic intermediate (V), which serves as starting material for a series of potential inhibitors (VI) of 5‐lipoxygenase.
ChemInform Abstract: Unprecedented Synthesis of N,N‐Divinylamines by Tf2NH‐Catalyzed Reaction of Ynamide with Ketimine.
Authors: Shindoh Naoya , Takemoto Yoshiji , Takasu Kiyosei
Published: July 2011

Title compounds (III) and (V) are synthesized from ynamides and acetophenone imines (II) via intermediate formation of keteniminium salt.
ChemInform Abstract: Efficient and Convenient Preparation of N‐Tosylimines Catalyzed by Indium Trichloride.
Authors: Deng Gui Sheng , Zou Jing Yuan , Sun Teng Fei
Published: July 2011

The simple procedure works successful in the condensation of aromatic and α,β‐unsaturated aldehydes.
ChemInform Abstract: Ionic Liquid/Potassium Hydroxide Catalyzed Solvent‐Free, One‐Pot Synthesis of Diarylglycolic Acids from Aromatic Aldehydes under Microwave.
Authors: Singh Neetu , Singh Satish Kumar , Khanna R. S. , Singh Krishna Nand
Published: July 2011

The pharmaceutical important target compounds are obtained within a short time and various functional groups are tolerated.
ChemInform Abstract: Nickel‐Mediated Decarbonylative Cross‐Coupling of Phthalimides with in situ Generated Diorganozinc Reagents.
Authors: Havlik Sarah E. , Simmons Jessica M. , Winton Valerie J. , Johnson Jeffrey B.
Published: July 2011

The process allows a new and efficient access to ortho‐substituted benzamides.
ChemInform Abstract: Oxalic Acid as a Simple and Efficient Organocatalyst for Three‐Component Synthesis of α‐Amino Nitriles.
Authors: Vahdat Seyed Mohammad , Khaksar Samad , Khavarpour Maryam
Published: July 2011

The optimized conditions including a short reaction time allow the preparation of a broad spectrum of aminonitriles without additional formation of undesired by‐products.
ChemInform Abstract: A General Route to Unsubstituted N‐Aryl and Heteroarylaminobenzenesulfonamides.
Authors: Lach Franck , Pasquet Marie‐Jeanne , Chabanne Mylene
Published: July 2011

The title compounds are prepared by Pd‐catalyzed N‐arylation of the sulfonamide and subsequent deprotection.
ChemInform Abstract: Pd2+ and Cu2+ Catalyzed Oxidative Cross‐Coupling of Mercaptoacetylenes and Arylboronic Acids.
Authors: Henke Adam , Srogl Jiri
Published: July 2011

The presence of the amide moiety in the thiosalicylamide substrates (I) is a prerequisite for a successful reaction outcome of the presented coupling.
ChemInform Abstract: An Efficient Method for the N‐Arylation of Phenylurea via Copper‐Catalyzed Amidation.
Authors: Gavade Sandip N. , Balaskar Ravi S. , Mane Madhav S. , Pabrekar Pramod N. , Shingare Murlidhar S. , Mane Dhananjay V.
Published: July 2011

Optimized reaction conditions are developed which avoid the use of toxic phosphine ligands.
ChemInform Abstract: A Novel and Efficient Synthesis of Alkyl Thiocyanates from Alkyl Halides in Water Using Phase Transfer Catalysts.
Authors: Gorjizadeh Maryam , Sayyahi Soheil
Published: July 2011

Both BPC and BPS are successfully applied to the reaction of primary alkyl halides with KSCN.
ChemInform Abstract: Broensted Acid Catalyzed Synthesis of Diarylmethanes under Non‐Genotoxic Conditions.
Authors: Mendoza Oscar , Rossey Guy , Ghosez Leon
Published: July 2011

The utility of benzylic acetates as benzylating agents for electron‐rich arenes and hetarenes is demonstrated using triflic acid and triflimide as catalysts.
ChemInform Abstract: Symmetric Diarylacetylenes: One‐Pot Syntheses and Solution Photoluminescence.
Authors: Brown Amy E. , Eichler Barrett E.
Published: July 2011

Stille coupling of aryl halides with bis(stannyl)acetylene gives diarylacetylenes, which are studied with UV‐vis and fluorescence spectroscopy.
ChemInform Abstract: Cu(OTf)2‐Catalyzed Arylmethylation of Terminal Alkynes with Benzylic Alcohols under Ligand‐, Base‐, and Additive‐Free Reaction Conditions.
Authors: Ren Kai , Li Pinhua , Wang Lei , Zhang Xiuli
Published: July 2011

Copper‐catalyzed cross coupling of arylacetylenes (II) with benzylic alcohols (I) proceeds smoothly in the absence of additives or ligands to give triarylalkynes (III) in excellent yields.
ChemInform Abstract: N‐Fluoro‐(3,5‐di‐tert‐butyl‐4‐methoxy)benzenesulfonimide (NFBSI): A Sterically Demanding Electrophilic Fluorinating Reagent for Enantioselective Fluorination.
Authors: Yasui Hiroyuki , Yamamoto Takeshi , Ishimaru Takehisa , Fukuzumi Takeo , Tokunaga Etsuko , Akikazu Kakehi , Shiro Motoo , Shibata Norio
Published: July 2011

Compared to NFSI (N‐fluorobenzenesulfonimide) NFBSI improves the enantioselectivity of the cinchona‐alkaloid catalyzed fluorination of silylenol ethers (I).
ChemInform Abstract: Discovery of Stabilized Bisiodonium Salts as Intermediates in the Carbon—Carbon Bond Formation of Alkynes.
Authors: Dohi Toshifumi , Kato Daishi , Hyodo Ryo , Yamashita Daisuke , Shiro Motoo , Kita Yasuyuki
Published: July 2011

In situ generated new bisiodonium salts are used for the conversion of aryl alkynes into functionalized spirocycles by treatment with a nucleophile.
ChemInform Abstract: Efficient One‐Pot Double Buchwald—Hartwig Coupling Reaction on 5‐Phenyl‐4‐phenylsulfonyl‐2,3‐dihydrofuran Derivatives.
Authors: Bouhlel Ahlem , Curti Christophe , Khoumeri Omar , Vanelle Patrice
Published: July 2011

One‐pot double Buchwald—Hartwig coupling reaction of dihydrofuran (I) with o‐aminobenzonitrile provides a mixture of dicoupled and monocoupled product.
ChemInform Abstract: Enantioselective Synthesis of α‐Methylene‐γ‐butyrolactams Using N‐tert‐Butanesulfinamides.
Authors: Dema Haythem K. , Foubelo Francisco , Yus Miguel
Published: July 2011

The indium‐mediated coupling of acrylate (I) with chiral aldimines (II) affords amino esters (III) in good yields and diastereoselectivities.
ChemInform Abstract: Asymmetric Michael Addition of 1‐Acetylindolin‐3‐ones to β‐Nitrostyrenes Catalyzed by Bifunctional Thioureas: A Simple Access to 2‐Functionalized Indoles.
Authors: Liu Yao‐Zong , Cheng Rui‐Ling , Xu Peng‐Fei
Published: July 2011

The thiourea allows highly stereoselective formation of 2‐functionalized indolinones and indoles.
ChemInform Abstract: Larock Heteroannulation of 2‐Bromoanilines with Internal Alkynes via Ligand and Salt Free Pd/C Catalyzed Reaction.
Authors: Batail Nelly , Dufaud Veronique , Djakovitch Laurent
Published: July 2011

The reaction of 2‐bromoanilines with internal silylated alkynes proceeds regioselectively to furnish 2,3‐disubstituted indoles.
ChemInform Abstract: A Practical and Enantioselective Approach to Tetrahydrocarbazoles by Asymmetric Organocatalysis.
Authors: Zhu Xiao‐Yu , An Xiao‐Lei , Li Chang‐Feng , Zhang Fu‐Gen , Hua Qiu‐Lin , Chen Jia‐Rong , Xiao Wen‐Jing
Published: July 2011

The intramolecular Friedel—Crafts‐type alkylation of ω‐indolyl α,β‐unsaturated aldehydes in the presence of chiral amines affords the title carbazole derivatives with up to 98% enantioselectivity.
ChemInform Abstract: Pd(II)‐Catalyzed Intramolecular Amidoarylation of Alkenes with Molecular Oxygen as Sole Oxidant.
Authors: Yip Kai‐Tai , Yang Dan
Published: July 2011

A wide range of tri‐ and tetracyclic indoline derivatives is prepared using ethyl nicotinate as a best ligand.
ChemInform Abstract: Rapid One‐Pot, Four‐Step Synthesis of Highly Fluorescent 1,3,4,5‐Tetrasubstituted Pyrazoles.
Authors: Willy Benjamin , Mueller Thomas J. J.
Published: July 2011

For each step almost equimolar, stoichiometric amounts of substrates are applied.
ChemInform Abstract: Dehydrogenation of 2‐Imidazolines with Sodium Periodate Catalyzed by Manganese(III) Tetraphenylporphyrin.
Authors: Kargar Hadi , Moghadam Majid , Mirkhani Valiollah , Tangestaninejad Shahram , Mohammadpoor‐Baltork Iraj , Nameni Iman
Published: July 2011

An efficient and mild method for the synthesis of the 2‐arylated and 2‐alkylated imidazoles (II) including an easy work‐up is developed.
ChemInform Abstract: 1‐Aryl‐4‐nitro‐1H‐imidazoles, a New Promising Series for the Treatment of Human African Trypanosomiasis.
Authors: Bourdin Trunz Bernadette , Jedrysiak Rafal , Tweats David , Brun Reto , Kaiser Marcel , Suwinski Jerzy , Torreele Els
Published: July 2011

Following a so‐called ANRORC reaction, several novel 1‐aryl‐4‐nitro‐1H‐imidazoles (III) are prepared.
ChemInform Abstract: New Bipolar Green Host Materials Containing Benzimidazole‐Carbazole Moiety in Phosphorescent OLEDs.
Authors: Park Jung Hwan , Kim Eun Kyung , El‐Deeb Ibrahim M. , Jung Su Jin , Choi Dae Hyuk , Kim Dong‐Ha , Yoo Kyung Ho , Kwon Jang Hyuk , Lee So Ha
Published: July 2011

New green host materials (VI) are obtained by attaching the electron transporting benzimidazole moiety to the hole transporting carbazole unit.
ChemInform Abstract: Asymmetric Synthesis of γ‐Siloxyenamides via Chiral Auxiliary‐Mediated Diastereoselective Coupling of Ynamides, Aldehydes, and Silane by Nickel Catalyst.
Authors: Saito Nozomi , Katayama Tomoyuki , Sato Yoshihiro
Published: July 2011

The nickel‐catalyzed three‐component coupling of optically active oxazolidinone‐derived ynamides (I) and (V), aldehydes, and silane (III) proceeds via oxanickelacycle to afford γ‐siloxyenamides (IV), (VI), and (VIII) in a regio‐ and stereoselective manner.
ChemInform Abstract: Tandem Catalysis: From Alkynoic Acids and Aryl Iodides to 1,2,3‐Triazoles in One Pot.
Authors: Kolarovic Andrej , Schnuerch Michael , Mihovilovic Marko D.
Published: July 2011

The process, which proceeds via decarboxylation/cycloaddition, renders possible the synthesis of a broad spectrum of triazoles and tolerates various functionalities.
ChemInform Abstract: Synthesis of Thiazolyltriazole Substituted Azetidinones as Antimicrobial Agents.
Authors: Baviskar B. A. , Shiradkar M. R. , Khadabadi S. S. , Deore S. L. , Bothara K. G.
Published: July 2011

The majority of the synthesized azetidinone derivatives (XI) (8 examples) shows marked antibacterial and antifungal activities.
ChemInform Abstract: Applications of 2‐Arylhydrazononitriles in Synthesis: Preparation of New Indole Containing 1,2,3‐Triazole, Pyrazole and Pyrazolo[1,5‐a]pyrimidine Derivatives and Evaluation of Their Antimicrobial Activities.
Authors: Behbehani Haider , Ibrahim Hamada Mohamed , Makhseed Saad , Mahmoud Huda
Published: July 2011

Synthesis and evaluation for antimicrobial activities against Gram‐negative and Gram‐positive bacteria as well as yeast are given.
ChemInform Abstract: Electron‐Transfer‐Induced Intermolecular [2 + 2] Cycloaddition Reactions Based on the Aromatic “Redox Tag” Strategy.
Authors: Okada Yohei , Nishimoto Asaki , Akaba Ryoichi , Chiba Kazuhiro
Published: July 2011

Aliphatic cyclic enol ethers undergo novel electron‐transfer‐induced [2 + 2] cycloaddition with unactivated olefins possessing aromatic “redox tag”.
ChemInform Abstract: Synthesis of Various N‐Substituted Derivatives with Different Heterocycles and Their Herbicidal Activity.
Authors: Mashelkar U. C. , Tungare Shefali S. , Bhagat Sachin
Published: July 2011

Selective oxidation of the aliphatic methylene‐group in coumarinylmethylcarboxylates (I) results in the formation of glyoxalate derivatives (II), which provide access to a variety of N‐heterocycles.
ChemInform Abstract: A Green One‐Pot Multicomponent Synthesis of 4H‐Pyrans and Polysubstituted Aniline Derivatives of Biological, Pharmacological, and Optical Applications Using Silica Nanoparticles as Reusable Catalyst.
Authors: Banerjee Subhash , Horn Alissa , Khatri Hari , Sereda Grigoriy
Published: July 2011

The three‐component reaction of 1,3‐diketo compounds with aldehydes and malononitrile provides 4H‐pyrans in high yields.
ChemInform Abstract: Design and Synthesis of 3‐(3‐Chloro‐4‐substituted phenyl)‐4‐(pyridine‐4‐yl)‐1H‐pyrazole‐1‐carboxamide Derivatives and Their Antiproliferative Activity Against Melanoma Cell Line.
Authors: El‐Gamal Mohammed I. , Oh Chang‐Hyun
Published: July 2011

3,4‐Diarylpyrazole derivatives possessing an amide moiety at C‐1 of the pyrazole ring are synthesized and screened for their antiproliferative activity against A375 human melanoma cell line.
ChemInform Abstract: The Preparation of Ketene Dithioacetals and Thiophenes from Chloropyridines Containing an Active Methylene Group.
Authors: Sturrock Keith R. , Bremner David H. , Wishart Grant
Published: July 2011

The base‐catalyzed abstraction of the methylene protons of chloropyridines (I) and the subsequent formation of a ketene dithioacetal dianion leads to, upon alkylation followed by treatment with sodium ethoxide, formation of thiophenes (V) and (VI), probably via a Thorpe‐type cyclization.
ChemInform Abstract: Reversible Dehydrogenation—Hydrogenation of Tetrahydroquinoline‐Quinoline Using a Supported Copper Nanoparticle Catalyst.
Authors: Mikami Yusuke , Ebata Kaori , Mitsudome Takato , Mizugaki Tomoo , Jitsukawa Koichiro , Kaneda Kiyotomi
Published: July 2011

Titania‐supported copper nanoparticles act as a heterogeneous catalyst for the reversible dehydrogenation and hydrogenation of tetrahydroquinoline/quinoline under an atmospheric pressure of hydrogen.This reversible organic hydride system can be applied under mild conditions and repeated with retention of high efficiency.
ChemInform Abstract: Preparation of New Nitrogen‐Bridged Heterocycles. Part 71. A New Synthetic Approach to Some Functionalized Cycl[3.2.2]azine Derivatives.
Authors: Muranaka Hideyuki , Kakehi Akikazu , Suga Hiroyuki , Itoh Kennosuke
Published: July 2011

Functionalized cyclazine derivatives (VI) are obtained by dehydrogenation of dihydrothiazinoindolizine derivatives (III) and (IV) in low to moderate yields.
ChemInform Abstract: Design, Synthesis and in vitro Antimicrobial Evaluation of Novel Imidazo[1,2‐a]pyridine and Imidazol[2,1‐b][1,3]benzothiazole Motifs.
Authors: Al‐Tel Taleb H. , Al‐Qawasmeh Raed A. , Zaarour Rania
Published: July 2011

Compared to control antibiotics amoxicillin, cefixime and fluconazole, newly synthesized compounds (III), (V), and (IX) exert strong inhibition of several bacterial and fungal strains.
ChemInform Abstract: Controlling Site Selectivity in Pd‐Catalyzed Oxidative Cross‐Coupling Reactions.
Authors: Lyons Thomas W. , Hull Kami L. , Sanford Melanie S.
Published: July 2011

This paper describes studies that address the factors controlling site selectivity in the Pd‐mediated oxidative coupling of 1,3‐disubstituted and 1,2,3‐trisubstituted arenes.
ChemInform Abstract: Novel Dihydropyrimidines and Its Pyrazole Derivatives: Synthesis and Pharmacological Screening.
Authors: Ramesh B. , Bhalgat Chetan M.
Published: July 2011

Dihydropyrimidines (I) and (II) and pyrazole derivatives (IV) are screened in vitro for their antioxidant, anti‐inflammatory, antibacterial, antifungal, and anthelmintic activity.
ChemInform Abstract: Synthesis and Biological Evaluation of Pyrido(2,3‐d)pyrimidine‐carboxylate Derivatives.
Authors: Shanmugasundaram P. , Harikrishnan N. , Aanandini M. Vijey , Kumar M. Sathish , Sateesh J. N.
Published: July 2011

Six new pyridopyrimidinecarboxylate derivatives (XI) and (XIV) are synthesized, which all show significant antibacterial, antifungal and antitumor activities.
ChemInform Abstract: Eco‐Friendly Solventless Synthesis of 5‐Indolylpyrimido[4,5‐d]pyrimidinones and Their Antimicrobial Activity.
Authors: Gupta Ragini , Jain Anshu , Joshi Rahul , Jain Meenakshi
Published: July 2011

The title compounds (IV) are conveniently obtained in a multi‐component reaction under microwave irradiation in dry media or using the grindstone technology.
ChemInform Abstract: Structure—Activity Relationships of New N‐Acylanthranilic Acid Derivatives as Plasminogen Activator Inhibitor‐1 Inhibitors.
Authors: Yamaoka Nagahisa , Kodama Hidehiko , Izuhara Yuko , Miyata Toshio , Meguro Kanji
Published: July 2011

New N‐acylanthranilic acid derivatives such as (I) are designed, synthesized and evaluated for their in vitro plasminogen activator inhibitory activities.
ChemInform Abstract: Synthesis of Some Chalcones and Pyrazolines Carrying Morpholinophenyl Moiety as Potential Antiinflammatory Agents.
Authors: Khalil Omneya M.
Published: July 2011

All synthesized compounds (III) and (IV) are screened for their antiinflammatory activity against carrageenan edema in albino rats.
ChemInform Abstract: Novel Benzimidazo[2,1‐c][1,4]thiazinone Derivatives with Potent Activity Against HSV‐1.
Authors: Galal Shadia A. , El‐Naem Shweekar I. , El‐Nezhawy Ahmed O. H. , Ali Mohamed A. , El‐Diwani Hoda I.
Published: July 2011

All compounds are tested for their activity against the herpes simplex virus 1.
ChemInform Abstract: Facile One‐Pot Synthesis of Novel 3‐Substituted‐1,6‐dihydro‐1,2,4‐triazin‐5‐(2H)‐ones from Fatty Acid Hydrazides and Their in vitro Antimicrobial Activity.
Authors: Farshori Nida Nayyar , Banday Mudasir Rashid , Ahmad Anis , Khan Asad Ullah , Rauf Abdul
Published: July 2011

The new triazine derivatives (III) show moderate to good antibacterial and antifungal activities.
ChemInform Abstract: Design and Synthesis of Potent and Selective Aldose Reductase Inhibitors Based on Pyridylthiadiazine Scaffold.
Authors: Zhu Changjin , et al. et al.
Published: July 2011

Several newly synthesized pyrido[2,3‐e]‐[1,2,4]thiadiazine 1,1‐dioxide derivatives (VII) are found to be potent aldose reductase inhibitors with compound (VIId) exhibiting the highest activity.
ChemInform Abstract: A Microwave‐Assisted Diastereoselective Multicomponent Reaction to Access Dibenzo[c,e]azepinones. Synthesis and Biological Evaluation.
Authors: Mehta Vaibhav P. , Modha Sachin G. , Ruijter Eelco , Van Hecke Kristof , Van Meervelt Luc , Pannecouque Christophe , Balzarini Jan , Orru Romano V. A. , Van der Eycken Erik
Published: July 2011

The reaction allows efficient and diastereoselective formation of dibenzoazepinones of type (IV).
ChemInform Abstract: Synthesis of C3 and CS Symmetric Cyclic Triglycerols.
Authors: Hamada Masahiro , Fujiwara Ryou , Kishimoto Takao , Nakajima Noriyuki
Published: July 2011

The first synthesis of cyclic polyglycerols as pure compounds is based on an intramolecular cyclization method.
ChemInform Abstract: Chemistry of a Geminal Frustrated Lewis Pair Featuring Electron Withdrawing C6F5 Substituents at Both Phosphorus and Boron.
Authors: Stute Annika , Kehr Gerald , Froehlich Roland , Erker Gerhard
Published: July 2011

The phosphine borane (I) represents a new frustrated Lewis pair (FLP) with a decreased Lewis basicity on the phosphorus atom.
ChemInform Abstract: Synthesis of Selenohydantoins from Isoselenocyanates and α‐Amino Acids.
Authors: Maeda Hajime , Sakata Koichi , Takashima Masaru , Watanabe Tatsuya , Mizukami Nobuteru , Honda Mitsunori , Segi Masahito
Published: July 2011

Selenohydantoins (III) and (V) are obtained by reaction of isoselenocyanates (I) with α‐amino acids (II) and (IV), resp.
ChemInform Abstract: Phloroglucinols from the Leaves of Eucalyptus globulus.
Authors: Kawabata Tetsuro , Hasegawa Tatsuya , Nojiri Yuka , Uchida Chiaki , Tsubata Tomoyuki , Kato Hikaru , Takano Fumihide , Ohta Tomihisa
Published: July 2011

Euglobal‐IX (I), a new acylphloroglucinol sesquiterpene, inhibits the catalytic activity of CYP3A4.
ChemInform Abstract: α,α‐Dichloroisoxazolidinones for the Synthesis and Chemoselective Peptide Ligation of α‐Peptide α‐Ketoacids.
Authors: Narumi Tetsuo , Bode Jeffrey W.
Published: July 2011

The present study is directed towards the preparation of enantiomerically enriched α,α‐dichloroisoxazolidinones and their use for the iterative synthesis of α‐oligopeptides.
ChemInform Abstract: Synthesis of a Chiral C3‐Symmetric Bowl‐Shaped Cyclohexapeptide Composed of Anthranilic Acid and Leucine.
Authors: Akazome Motohiro , Enzu Masashi , Goto Yohei , Matsumoto Shoji
Published: July 2011

The cyclic hexapeptide (I) is synthesized from 2‐nitrobenzoic acid and leucine via coupling of three dipeptide intermediates.
ChemInform Abstract: Monosaccharide as a Central Scaffold Toward the Construction of Salicylate‐Based Bidentate PTP1B Inhibitors via Click Chemistry.
Authors: Tang Yan‐Hui , Hu Min , He Xiao‐Peng , Fahnbulleh Sando , Li Cui , Gao Li‐Xin , Sheng Li , Tang Yun , Li Jia , Chen Guo‐Rong
Published: July 2011

A series of bidentate triazolyl glucosides bearing two salicylic precursors on 2,6‐, 3,4‐, 4,6‐, and 2,3‐ position of the central glucosyl scaffold is prepared via click chemistry as key step.
ChemInform Abstract: Tricalysionoside A, a Megastigmane Gentiobioside, Sulfatricalysines A—F, and Tricalysiosides X—Z, ent‐Kaurane Glucosides, from the Leaves of Tricalysia dubia
Authors: Shitamoto Junko , Sugimoto Sachiko , Matsunami Katsuyoshi , Otsuka Hideaki , Shinzato Takakazu , Takeda Yoshio
Published: July 2011

isolation and structural elucidation of one new megastigmane gentiobioside, tricalysionoside A (I), three sulfates, sulfatricalysines A‐C and three new ent‐kaurane glucosides such as tricalysioside Z (II)
ChemInform Abstract: A Concise Synthesis of the Aporhoeadane Skeleton.
Authors: Piko Bridget E. , Keegan Amy L. , Leonard Michael S.
Published: July 2011

A four‐step synthesis of the desired core structure (VII) is achieved from aromatic amine (I) and ninhydrin (II).
ChemInform Abstract: Convenient Synthesis of the Key Intermediate for Dihydrocorynantheol and Protoemetinol from the Monoacetate of 4‐Cyclopentene‐1,3‐diol.
Authors: Kobayashi Yuichi , Yagi Kaori , Kaneko Yuki
Published: July 2011

Stereoselective installation of two side chains affords the key lactone (VI) in a 60% overall yield from monoacetate (I).
ChemInform Abstract: Two Novel Benzastatin Derivatives, JBIR‐67 and JBIR‐73, Isolated from Streptomyces sp. RI18.
Authors: Motohashi Keiichiro , Nagai Aya , Takagi Motoki , Shin‐ya Kazuo
Published: July 2011

The new benzastatin derivatives, JBIR‐67 (I) and JBIR‐73 (II) show weak cytotoxicity against human cervical carcinoma HeLa cell lines.