bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Aminoglycoside Antibiotics ‐ Fortamine Aglyca. Total Synthesis, Optical Resolution, Chemical Modifications.
Authors: SCHUBERT J. , SCHWESINGER R. , KNOTHE L. , PRINZBACH H.
Published: May 2016

An efficient synthesis for the de‐O‐methylfortamines (X) and (XI) as well as for the fortamines (XV), (XVI) is developed studying several model reactions.
ChemInform Abstract: Studies of the Antitumor Activity of (2‐Alkoxyalkyl)‐ and 2‐(Alkoxyalkenyl)phosphocholines.
Authors: BONJOUKLIAN R. , PHILLIPS M. L. , KUHLER K. M. , GRINDEY G. B. , POORE G. A. , SCHULTZ R. M. , ALTOM M. G.
Published: May 2016

Starting with the diols (I) or the ether (IV), the phosphocholines (III) and (VII) are obtained.
ChemInform Abstract: CdTe Semiconductor Electrochemical Behavior. Scope of Application as an Analytical Sensor.
Authors: ELSIRAFY A. A. , EL‐DESSOUKI M. S. , EL‐BASIOUNY M. S.
Published: May 2016

The applicability of n‐CdTe as an electrochemical sensor for pH and acid‐base as well as redox titrations has been proved.
ChemInform Abstract: Effect of Aluminum vs. Photoresist Masking on the Etching Rates of Silicon and Silicon Dioxide in CF4/O2 Plasmas.
Authors: FEDYNYSHYN T. H. , GRYNKEWICH G. W. , HOOK T. B. , LIU M.‐D. , MA T.‐P.
Published: May 2016

It is shown that the etch rate of aluminum masked silicon is enhanced relative to photoresist masking, whereas the etch rate of SiO2 is suppressed by the aluminum mask.
ChemInform Abstract: Surface Charge Studies on Lead Borosilicate Glass Containing Trace Sodium
Authors: SHIMBO M. , FURUKAWA K. , TANZAWA K. , FUKADA K.
Published: May 2016

(a few to about 100 ppm Na) have been carried out by measurements of the C‐V characteristics of metal‐glass‐silicon (MGS) capacitors and stability tests of glass‐passivated diodes.
ChemInform Abstract: Overlayer Formation as a Source of Stability in the N‐Type Photoelectrochemical Cell. The N‐CdS/Fe(CN)4‐/3‐ 6 Cell.
Authors: RUBIN H.‐D. , ARENT D. J. , HUMPHREY B. D. , BOCARSLY A. B.
Published: May 2016

The stability of n‐CdS in a Fe(CN)4‐/3‐ 6 electrolyte is shown to be due to the formation of a MxCdFe(CN)6 overlayer.
ChemInform Abstract: 119Sn NMR Studies of Some Pseudohalogeno Derivatives of (SnX6)2‐ (X: Cl or Br).
Authors: DILLON K. B. , MARSHALL A.
Published: May 2016

The results of 119Sn NMR studies in solution are indicative of the existence of several (SnX6‐nYn)2‐ (X: Cl, Br; Y: NCS, CN).
ChemInform Abstract: Determination of the Deuterium Position in DNb6I11.
Authors: SIMON A. , STOLLMAIER F. , GREGSON D. , FUESS H.
Published: May 2016

A sample of composition D0.45Nb6I11, prepared by heating a Nb6I11 crystal in D2 is shown to consist of epitaxially intergrown Nb6I11 and DNb6I11, i.e. the deuteration reaction does not reach the inner part of the crystal.
ChemInform Abstract: Crystal Structure of Coesite, a High‐Pressure Form of SiO2, at 15 and 298 K from Single‐Crystal Neutron and X‐Ray Diffraction Data: Test of Bonding Models.
Authors: SMYTH J. R. , SMITH J. V. , ARTIOLI G. , KVICK A.
Published: May 2016

Natural coesite, a dense variety of SiO2 stable between ∼ 2.5 and 9.5 GPa, crystallizes in space group C2/c. Cell dimensions are determined at 15 and 292 K by neutron diffraction and at 298 K by XRD.
ChemInform Abstract: Sulfur Compounds. Part 105. Low Temperature Raman Spectra of Dichlorosulfane (SCl2), Tetrachlorosulfurane (SCl4), Dichlorodisulfane (S2Cl2) and Dichlorodiselane (Se2Cl2).
Authors: STEUDEL R. , JENSEN D. , PLINKE B.
Published: May 2016

The Raman spectrum of commercial "SCl2" shows strong signals assigned to SCl2 and S2Cl2 vibrations and weak Cl2 lines at 25 °C, but strong SCl2 and SCl4 signals at ‐100 °C. Thus, the intense Raman effect of SCl4 can be used for the detection of small amounts of Cl2 in SCl2.
ChemInform Abstract: IR Spectroscopic Study of the Interaction of Ammonia and Oxygen at the Surface of MgO‐CoO Solid Solutions
Authors: ESCALONA PLATERO E. , COLUCCIA S. , ZECCHINA A.
Published: May 2016

indicate the formation of NO2‐ and NO3‐ species adsorbed on the surface by the reaction of O2 and NH3 in the adsorbed state.
ChemInform Abstract: 81Br Nuclear Quadrupole Resonance of Cs2ZnBr4 and Crystal Stability of Compounds of A2MX4 Type.
Authors: NAKAYAMA H. , NAKAMURA N. , CHIHARA H.
Published: May 2016

The temp. dependences of the NQR frequencies and quadrupolar relaxation times indicate that the librational motion of the (ZnBr4)2‐ tetrahedron is highly anisotropic; only the libration of the anion about the a‐axis is highly excited.
ChemInform Abstract: Effect of Sb on the Electrochemical Properties of Pb/PbSO4/H2SO4 and Pb/PbO/PbSO4/H2SO4 Electrodes.
Authors: PAVLOV D. , MONAKHOV B.
Published: May 2016

Sb is dissolved during anodic polarization of Pb‐Sb electrodes resulting in a change of the phase composition of the electrode surface.
ChemInform Abstract: Hot Corrosion of Nickel‐Based Ternary Alloys and Superalloys for Gas Turbine Applications. Part 1. Corrosion in SO2/O2 Atmospheres. Part 2. The Mechanism of Corrosion in SO2/O2 Atmospheres.
Authors: SIDKY P. S. , HOCKING M. G.
Published: May 2016

Hot corrosion studies of In738 superalloy, Ni‐22 Cr control alloy as well as Ni‐20 Cr‐X ternary alloys (X: 3 Al, 4 Mo, 0.3 Si, or 5 V) in SO2/O2 show that the corrosion rates at 700 °C are much greater than those at 900 °C, the corrosion rate is not altered by a change in the SO2/O2 ratio, and that Al, Si and V additions are beneficial at 700 °C, whereas at 900 °C, V addition enhances the corrosion rate of the control alloy due to the formation of a molten phase.
ChemInform Abstract: Effect of Additives on the Surface Area of Oxide Supports for Catalytic Combustion.
Authors: MACHIDA M. , EGUCHI K. , ARAI H.
Published: May 2016

The effect of additives on the surface area of Al2O3‐, ZrO2‐, and MgO‐based oxides and the catalytic activity of CoO supported on such oxides for CH4 combustion have been investigated.
ChemInform Abstract: On KCrF4.
Authors: KISSEL D. , HOPPE R.
Published: May 2016

Single crystals of KCrF4 are obtained besides other products by annealing a mixture of KF, CuF2, and CrF3 (Au tube, 750 °C, 60 d).
ChemInform Abstract: Zinc and Silver Ion Coordination by Pyrido(1,2‐a)pyrimidine Derivatives.
Authors: VEBER M. , KATONA‐BALAZS J. , BURGER K. , KALOY K. , HERMECZ I. , MESZAROS Z.
Published: May 2016

The protonation and zinc and silver ion coordination equilibria of the pyrido(1,2‐a)pyrimidine derivatives (I)‐(V) are studied by polarographic, potentiometric and spectrophotometric methods.
ChemInform Abstract: Catalysis of Electrochemical Reactions at Redox Polymer Coated Electrodes. Mediation of the Fe(III)/Fe(II) Oxido‐Reduction by a Polyvinylpyridine Polymer Containing Coordinatively Attached Bisbipyridine Chlororuthenium Redox Centers.
Authors: ANDRIEUX C. P. , HAAS O. , SAVEANT J.‐M.
Published: May 2016

The polymer (I) catalyzes the oxidation of Fe(II) into Fe(III) in 1 M HCl in a quite efficient manner both in terms of current and potential.
ChemInform Abstract: Role of Heme Vinyl Groups in Cytochrome b5 Electron Transfer.
Authors: REID L. S. , LIM A. R. , MAUK A. G.
Published: May 2016

Discussion of the mechanism by analyzing the oxidation‐reduction equilibrium and Fe(EDTA)2‐ reduction kinetics of deuteroheme‐substituted cytochrome b5.
ChemInform Abstract: Asymmetric Simmons‐Smith Reactions Using Homochiral Protecting Groups.
Authors: MORI A. , ARAI I. , YAMAMOTO H. , NAKAI H. , ARAI Y.
Published: May 2016

The α,β‐unsaturated aldehydes (I) are converted to the acetals (IV) or (VI) by the reactions of the diethylacetals (II) with the chiral dialkyl tartrates (III) or with chiral 2,4‐pentanediol.
ChemInform Abstract: Rearrangements of N‐Hydroxy β‐Lactams.
Authors: BISWAS A. , EIGENBROT C. , MILLER M. J.
Published: May 2016

β‐Lactamase enzymes are responsible for microbial resistance towards β‐lactam antibiotics.
ChemInform Abstract: Synthesis of 1,1‐Dihaloalkanes.
Authors: MARTINEZ A. G. , FERNANDEZ A. H. , ALVAREZ R. M. , FRAILE A. G. , CALDERON J. B. , BARCINA J. O. , HANACK M. , SUBRAMANIAN L. R.
Published: May 2016

The aldehydes (I) are converted to the 1,1‐bis(trifluoromethylsulfonyloxy)alkanes (II).
ChemInform Abstract: Synthesis of the Isomeric Esters of 4‐Bromo‐2,4‐hexadienoic Acid.
Authors: IKRINA M. A. , BARYSHEVA N. A. , SIMONOV V. D. , TALZI V. P.
Published: May 2016

The dehydrobromination of the erythro‐4,5‐dibromohexenoates (I) is studied.
ChemInform Abstract: Photooxidation of Dispiro(2.0.2.4)deca‐7,9‐diene and Its Analogues: Synthesis and Properties of New Nonenolizable Cyclohex‐2‐ene‐1,4‐diones.
Authors: DE MEIJERE A. , KAUFMANN D. , ERDEN I.
Published: May 2016

Photooxidation of the title dienes (I) and (III) yields the endoperoxides (II) and (IV), respectively.
ChemInform Abstract: S,S‐Dialkyl Dithiocarbonates as a Convenient Source of Alkanethiols: An Improved Synthesis of Alkylthiocarboxylic Acids.
Authors: CADAMURO S. , DEGANI I. , FOCHI R. , REGONDI V.
Published: May 2016

S,S‐Dialkyl dithiocarbonates (I) are used as source of alkanethiols which are coupled with the α,β‐unsaturated carboxylic acids (II) and (IV) to yield the β‐alkylthiocarboxylic acids (III) and (V) respectively.
ChemInform Abstract: Synthesis of Carbocyclic Spiro Compounds from Isochroman Derivatives via Intramolecular Aldol Reaction.
Authors: HASHIGAKI K. , YOSHIOKA S. , YAMATO M.
Published: May 2016

Coupling the 1‐ethoxychroman (I) with the cyclic ketones (II), followed by ring cleavage and oxidation, yields the aldehydes (VI).
ChemInform Abstract: 1,2‐Disubstituted Derivatives of Acenaphthene. Part 5. Synthesis of 5,6‐Dichloroacenaphthene Oxide.
Authors: ANIKIN V. F. , LEVANDOVSKAYA T. I. , GIL'EN KH.
Published: May 2016

The monoacetate (I) is converted to the halohydrins (II) which yield the title compound after treatment with base.
ChemInform Abstract: Preparation of Some 2,3‐Dideoxylactones by an Unusual Catalytic Hydrogenolysis.
Authors: LUNDT I. , PEDERSEN C.
Published: May 2016

The title compounds (II), (IV), (V), and ent‐(V) are obtained by the hydrogenolysis of the 2‐bromo‐2‐deoxyaldono‐1,4‐lactones (I), (III), (IV), and (VI) in the presence of palladium.
ChemInform Abstract: Alkaloids Asymmetric Synthesis from (S)‐Pyroglutamic Acid. Part 2. Attempted Asymmetric Total Synthesis of trans‐5‐Ethyl‐2‐n‐heptylpyrrolidine.
Authors: MARCO J. L.
Published: May 2016

(S)‐Pyroglutamic acid (I) is reduced to yield the corresponding alcohol which is converted to the derivatives (II).
ChemInform Abstract: Synthesis of 2‐Substituted Benzimidazole‐5‐carbamates as Potential Antifilarial Agents.
Authors: RAM S. , WISE D. S. , TOWNSEND L. B.
Published: May 2016

Coupling the diamine (I) with the phenylacetic acids (II) gives the benzimidazoles (III).
ChemInform Abstract: Cyclization Reactions of Nitriles. Part 22. Reactions of Arylidenecyanothioacetamides with Unsymmetric 1,3‐Dicarbonyl Compounds. Molecular and Crystal Structure of 5‐Ethoxycarbonyl‐6‐methyl‐4‐(4‐fluorophenyl)‐3‐cyano‐2(1H)‐pyridinethione.
Authors: SHARANIN YU. A. , SHESTOPALOV A. M. , RODINOVSKAYA L. A. , NESTEROV V. N. , SHKLOVER V. E. , STRUCHKOV YU. T. , PROMONENKOV V. K. , LITVINOV V. P.
Published: May 2016

The reactions between the arylidenecyanothioacetamides (I) and the 1,3‐dicarbonyl compounds (II) in the presence of the secondary amines (III) yield exclusively the pyridine‐2‐thiolates (IV).
ChemInform Abstract: Reactions with α‐Substituted Cinnamonitriles. A Novel Synthesis of Hexa‐Substituted Pyridines.
Authors: HAMMOUDA H. A. , EL‐REEDY A. M. , HUSSAIN S. M.
Published: May 2016

The 2‐substituted cinnamonitriles (I) are coupled with the 1,3‐dicarbonyl or 1,3,5‐tricarbonyl derivatives (II) and (X) to produce various cyclization products such as (III), (VI), (VIII), and (XI) ‐ (XIV).
ChemInform Abstract: A Reinvestigation of the Synthesis of 3H‐(1,2)Diazepino(5,6‐b)indoles. The Synthesis of Pyrido(4,3‐b)indoles.
Authors: KARRICK G. L. , PEET N. P.
Published: May 2016

The methylphenylhydrazine (I) reacts with the acetonedicarboxylate (II), yielding the compound (III) which is cyclized to form the indoledicarboxylate (IV).
ChemInform Abstract: 2‐Methylpyridinium Salts as 1,4‐Dinucleophiles. Part 2. Westphal Condensation with Substituted Pyridinium Substrates.
Authors: EZQUERRA J. , ALVAREZ‐BUILLA J.
Published: May 2016

The N‐ethoxycarbonylmethyl pyridinium derivatives (II), (IV), (VI), and (VIII) are coupled with the 1,2‐diketones (I) to yield the cyclization products (III), (V), (VII), and (IX).
ChemInform Abstract: Cycloaddition Reactions of Ketoimines. Part 2. Synthesis of Substituted Phenanthridines and Cyclopenta(c)quinolines.
Authors: LUCCHINI V. , PRATO M. , SCORRANO G. , TECILLA P.
Published: May 2016

The keto imines (I) are coupled with cyclopentadiene (II) to yield the tetrahydropyridines (III).
ChemInform Abstract: Synthesis and Properties of Trifluoromethylthio‐Substituted Pyrimidines.
Authors: HAAS A. , LIEB M.
Published: May 2016

5‐Trifluoromethylthiobarbituric acid (I) and the corresponding uracil (III) are halogenated to form the chloro and bromo derivatives (II) and (IV) respectively.
ChemInform Abstract: Synthesis of Some New Pyrimido(1,6‐a)pyrimidines. Isolation of Stable Covalent Hydrated Pyrimido(1,6‐a)pyrimidines.
Authors: PEGIADOU‐KOEMTJOPOULOU S.
Published: May 2016

5‐Phenyl‐4‐aminopyrimidine (I) reacts with the malonic acids (II) in the presence of acetanhydride, yielding the cyclization products (III) and (IV).
ChemInform Abstract: Synthesis of Morpholine Derivatives of Amino Acids by Ozonolysis and Reductive N‐Alkylation.
Authors: KANAMOTO M. , HAMADA M. , KAWAGUCHI M. , YAMAMOTO Y. , ODA J.
Published: May 2016

Ozonolysis of the furan derivative (I) followed by the title alkylation with the (S)‐configurated esters (II) yields the morpholine derivatives (III).
ChemInform Abstract: Acylation of β‐Enaminoesters. Regio‐ and Stereoselective Formation of N‐ or C‐Acyl Enaminoesters.
Authors: BRUNERIE P. , CELERIER J.‐P. , PETIT H. , LHOMMET G.
Published: May 2016

The cyclic enaminoesters (I) react with the acylchlorides (II) to give the acyl derivatives (IIIa), (IVb), (Vb), and (Vc).
ChemInform Abstract: A Simple One‐Pot Synthesis of Silylated and Acylated Cyanohydrins.
Authors: YONEDA R. , SANTO K. , HARUSAWA S. , KURIHARA T.
Published: May 2016

Carbonyl compounds (I) react with chlorotrimethylsilane (II) or the acyl chlorides (IV) in the presence of lithium cyanide to produce the silylated or acylated cyanohydrins (III) and (V) respectively.
ChemInform Abstract: Nucleophilic Addition of Lithiated Phenyl Trimethylsilylmethyl Sulfide to Activated Olefins. A Facile Synthesis of 2‐(Functionally) Substituted Silylcyclopropanes.
Authors: SCHAUMANN E. , FRIESE C. , SPANKA C.
Published: May 2016

The lithio derivative (I) of phenyl trimethylsilylmethyl sulfide is coupled with the activated olefins (II) to produce the silylcyclopropanes (III).
ChemInform Abstract: Synthesis and X‐Ray Structure Analysis of Phenanthro(9,10‐c)‐1,2,5‐telluradiazole.
Authors: NEIDLEIN R. , KNECHT D. , GIEREN A. , RUIZ‐PEREZ C.
Published: May 2016

The title compound (II) can be prepared from the selenium analogue as shown.
ChemInform Abstract: New Organonitrogen‐Derivatized Polyoxomolybdate Anion Clusters. Syntheses and Characterization of Tetranuclear and Octanuclear Oxomolybdates Containing Coordinatively Bound Organohydrazido(2‐) Units: (Mo4O10(OCH3)2(NNPh2)2)2‐ and (Mo8O16(OCH3)6(NNMePh)6)2‐.
Authors: SHAIKH S. N. , ZUBIETA J.
Published: May 2016

The 1:6 molar reaction of the octamolybdate (I) with disubstituted hydrazines NH2NPhR at room temp. (24 h) affords the tetranuclear methoxo‐bridged bis(hydrazido) clusters (II).
ChemInform Abstract: New Molybdenum and Iron Phosphoranides. Mechanism and Stereochemistry of the Rearrangement and Migration of a Phosphorus‐Bound Allylic Group Into an Iron‐Bound Vinylic Group.
Authors: VIERLING P. , RIESS J. G.
Published: May 2016

The reaction of the bicyclic phosphoranes (III), prepared as shown, with the Mo complex (IV) results in substitution of one CO ligand and coordination of the tautomeric open form of (III) through the P atom to give the phosphine derivatives (V).
ChemInform Abstract: Mono(aryl)cobalt(II) Compounds Stabilized by Bis Ortho Chelation.
Authors: VAN DER ZEIJDEN A. A. H. , VAN KOTEN G.
Published: May 2016

The reaction of (I) with the complexes (II) yields the air‐sensitive, paramagnetic complexes (III).
ChemInform Abstract: Hydrazone Ligands Derived from Acyl‐ and Aroylferrocenes and Their Complexes with Cobalt(II) Halides.
Authors: MARKOPOULOS J. , MARKOPOULOU O. , BETHELL D. , NICHOLLS D.
Published: May 2016

The 1:4 molar reaction of CoCl2 or CoBr2 with the acylferrocene hydrazones L in refluxing absolute ethanol leads to crystalline products of the composition (I).
ChemInform Abstract: Synthesis of Mixed Sphere β‐Diketonate Nickel(II) Complexes.
Authors: FAVERO G. , CORAIN B. , BASATO M. , ISSA S.
Published: May 2016

The cationic Ni(II) complexes of the type (II) are prepared from the bis(diketonato)‐Ni(II) complexes (I) and corresponding diphosphines (molar ratio 1:1) or diamines (molar ratio 1:2) as shown.
ChemInform Abstract: Solution and Solid State Investigation of the Cu(II)‐N‐Acetyl‐L‐glutamine System and Its N‐Methylimidazole Adduct.
Authors: MENABUE L. , SALADINI M.
Published: May 2016

Interactions of N‐acetyl‐L‐glutamine HL with Cu(II) ion in aqueous and H2O/MeOH (1:1) solutions and in solid state are investigated.
ChemInform Abstract: Polyfunctional Molecules. Part 97. Coordination Chemistry of Lithium‐bis(diphenylphosphino)amide, Bis(diphenylphosphino)amine, and Tris(diphenylphosphino)amine.
Authors: ELLERMANN J. , WEND W.
Published: May 2016

The Li bis(phosphino)amide (II) reacts with Au complex (I) to give the already known complex (III) whose dimeric structure is confirmed by mass spectroscopy.
ChemInform Abstract: Activation of the CN Triple Bond of Substituted Benzonitriles in the Presence of Ru3(CO)12, Acetic Acid and Molecular Hydrogen. Crystal Structure of (μ‐H)2Ru3(CO)9(μ3‐NCH2C6H4OMe).
Authors: MICHELIN LAUSAROT P. , OPERTI L. , VAGLIO G. A. , VALLE M. , TIRIPICCHIO A. , TIRIPICCHIO CAMELLINI M. , GARIBOLDI P.
Published: May 2016

Reactions of Ru3(CO)12 (I) with p‐methoxy‐ and p‐nitrobenzonitrile (II) are studied in refluxing cyclohexane and the complexes formed are characterized by IR, 1H NMR, and mass spectroscopy.
ChemInform Abstract: Synthesis and Characterization of Bis(salicylideneaminato)palladium(II) Complexes. Molecular Structure of Bis(N‐(n‐butyl)(3‐benzyloxy)‐2‐salicylideneaminato)palladium(II), (Pd(C18H20NO2)2).
Authors: GHEDINI M. , PELLEGRINO C. , ARMENTANO S. , DE MUNNO G. , BRUNO G.
Published: May 2016

Schiff bases are prepared by treatment of salicylaldehyde or 2,3‐dihydroxybenzaldehyde with long chain aliphatic amines in refluxing ethanol.
ChemInform Abstract: Ester Groups as Ligands in Heavy Metal Chelates. Part 9. Heavy Metal Chelates of α‐Cyano‐β‐amino‐dithioacrylates.
Authors: HARTUNG J. , WEBER G. , BEYER L. , SZARGAN R. , KREUTZMANN J.
Published: May 2016

The title ligands (V) are prepared as shown in the scheme.
ChemInform Abstract: Iridium(I) Dimers with Bridging N,N′‐Di‐p‐tolylformamidine. X‐Ray Molecular Structure of Ir2(μ‐p‐CH3C6H4NCHN‐p‐C6H4CH3)(μ‐NH‐p‐C6H4CH3)(C8H14)2.
Authors: COTTON F. A. , POLI R.
Published: May 2016

The reaction of the Ir(I) dimer (I) with the potassium salt (II) of N,N'‐di‐p‐tolylformamidine (generated in situ) in neat toluene leads to formation of the binuclear product (III) with two bridging formamidinato ligands.
ChemInform Abstract: Dehydrogenation of Cyanamides. An Approach to Cyanimides and Carbonyl Compounds.
Authors: CARRAU R. , FREIRE R. , HERNANDEZ R. , SUAREZ E.
Published: May 2016

The cyanamides (II), prepared from the primary amines (I), are oxidized by lead tetraacetate to form the cyanimides (III) which are hydrolyzed, yielding the ketones (IV).
ChemInform Abstract: Imination of N‐Methylpyridinium Salts by Liquid Ammonia‐Potassium Permanganate. A New Synthesis of Nudiflorine.
Authors: BUURMAN D. J. , VAN DER PLAS H. C.
Published: May 2016

Oxidative imination of pyridinium salts such as (I) with KMnO4/liquid ammonia proceeds via amino derivatives such as (II).
ChemInform Abstract: A Convenient Synthesis of 1′‐Alkyl‐ and 1′‐Benzylthiaminium Salts.
Authors: KARIMIAN K. , MOHANAZADEH F.
Published: May 2016

The alkylation of the thiamines (I) with the alkyl halides (II) leads to quaternization at N‐1'.
ChemInform Abstract: Oxalyl Complexes in Organic Synthesis
Authors: VINOGRADOV M. G. , KOVALEV I. P. , NIKISHIN G. I.
Published: May 2016

Review: (180 refs.
ChemInform Abstract: The Bonding Conditions in Crystalline Phases of RbOH and RbOD
Authors: JACOBS H. , MACH B. , LUTZ H.‐D. , HENNING J.
Published: May 2016

have been investigated between 15 K and m.p. by means of X‐ray and neutron diffraction, IR and Raman spectroscopy as well as by calorimetric methods.
ChemInform Abstract: Solubility of Hydrogen in Ti3Cu.
Authors: RAJALAKSHMI N. , RAJU U. V. V. , RAO K. V. S. R.
Published: May 2016

The hydrogen absorption of Ti3Cu has been investigated in the temp. range 575‐850 °C at H2 pressures between 0.001 and 0.925 bar.
ChemInform Abstract: Aluminium Distribution in the Bulk and on the Surface of Y Zeolites Dealuminated with SiCl4 Vapour. Influence of Conditions of Dealumination.
Authors: KUBELKOVA L. , DUDIKOVA L. , BASTL Z. , BORBELY G. , BEYER H. K.
Published: May 2016

The dealumination of zeolite Y with SiCl4 is not only dependent on the reaction temp. but also depends on subsequent washing; the Si/Al ratio both in the bulk and on the surface increases with efficiency of washing (H2O > EtOH > EtOH and NH4OH/NH4Cl buffer).
ChemInform Abstract: Preparation and Cristallographic Study of Two New Adducts Between Telluric Acid and Alkali Metal Cyclotetraphosphates: K4P4O12·Te(OH)6·2 H2O and Rb4P4O12·Te(OH)6·2 H2O.
Authors: AVERBUCH‐POUCHOT M.‐T. , DURIF A.
Published: May 2016

The title compounds have been prepared by slow evaporation of a equimolar aqueous solution of the alkali metal cyclotetraphosphate and telluric acid.
ChemInform Abstract: Preparation of Ytterbium Trihydride Without Hydrogen Overpressure.
Authors: DRULIS H. , DRULIS M. , BORKOWSKA Z.
Published: May 2016

It is demonstrated that, under appropriate conditions of temp. and time, the f.c.c. β‐phase of ytterbium trihydride can be prepared besides some orthorhombic dihydride at hydrogen pressures lower than 1 atm.
ChemInform Abstract: A 57Fe Moessbauer Study of Phosphaferricenium Ions.
Authors: ROBERTS R. M. G. , SILVER J. , WELLS A. S.
Published: May 2016

Oxidation of the phosphaferrocenes (I)‐(III) with tetracyanoethylene gives the corresponding phosphaferricenium salts.
ChemInform Abstract: Magnetic Exchange Interactions in Nitroxyl Biradicals Bridged by Metal‐Metal Bonded Complexes: Structural, Magnetochemical, and Electronic Spectral Characterization of Tetrakis(perfluorocarboxylato)dimetal(II) Complexes of Rhodium and Molybdenum Containing Axially Coordinated Nitroxyl Radicals.
Authors: FELTHOUSE T. R. , DONG T.‐Y. , HENDRICKSON D. N. , SHIEH H.‐S. , THOMPSON M. R.
Published: May 2016

The Rh(II) perfluorocarboxylates are prepared through a carboxylate exchange procedure with Rh(II) acetate.
ChemInform Abstract: Sodium Salts of the Bis‐μ‐peroxo‐hexacarbonatodicerate(IV) Anion. Crystal Structure of Na8(Ce(O2)(CO3)3)2·18 H2O.
Authors: BARNES J. C. , BLYTH C. S. , KNOWLES D.
Published: May 2016

The addition of sodium nitrilotriacetate to a solution of ((Ce(O2)(CO3)3)2)8‐ in saturated aqueous Na2CO3 fails to give a nitrilotriacetate but gives the title complex which crystallizes in the space group P21/c with Z=4.
ChemInform Abstract: pH‐Induced Intramolecular Electron Transfer.
Authors: NEYHART G. A. , MEYER T. J.
Published: May 2016

It is shown that in the mixed‐valence dimer (I) which contains both an aquo‐based, pH‐dependent couple and a pH‐independent couple, changes in the pH can be utilized to induce intramolecular electron transfer across the ligand bridge.
ChemInform Abstract: Transformations of 1‐Vinylcyclobutene.
Authors: VDOVIN V. M. , FINKEL'SHTEIN E. SH. , SHELKOV A. V. , YATSENKO M. S.
Published: May 2016

Impulse pyrolysis of the vinylcyclobutene (I) at 335°C gives 3‐methylene pentadiene‐1,4 (II).
ChemInform Abstract: A New, Convenient Synthesis of 1,6‐Diaryl‐2‐thioxoperhydro‐4‐pyrimidinones: Reaction of 3‐Phenyl‐2‐propenoyl Isothiocyanate with Aromatic and Heteroaromatic Amines.
Authors: HAFEZ E. A. A. , ELMOGHAYAR M. R. H. , RAMIZ M. M. M.
Published: May 2016

The title isothiocyanate (I) reacts with the amines (II), (VI), (VIII) or (X) to afford the products (III), (VII), (IX) or (XI).
ChemInform Abstract: An Approach to Tetrahydrobenz(b,d)pyrans and Hexahydrophenanthridines by Reaction of Dilithiated Phenol and Aniline with Pulegone.
Authors: PEDAJA P. , WESTERLUND C. , HALLBERG A.
Published: May 2016

The o‐lithiated phenol ethers (I) are coupled with pulegone (II), yielding the dibenzopyrane (III) which is also obtained from the dilithio compound (IV) and (II).
ChemInform Abstract: Photochemical Reactions of N‐Methylnaphthalene‐2,3‐dicarboximide with Alkenes.
Authors: KUBO Y. , SUTO M. , ARAKI T. , MAZZOCCHI P. H. , KLINGLER L. , SHOOK D. , SOMICH C.
Published: May 2016

The photochemical reactions of the imide (II) with the olefins (I) are studied.
ChemInform Abstract: Bond Dissociation Energies and Radical Heats of Formation in CH3Cl, CH2Cl2, CH3Br, CH2Br2, CH2FCl, and CHFCl2.
Authors: TSCHUIKOW‐ROUX E. , PADDISON S.
Published: May 2016

(TSCHUIKOW‐ROUX, E.; PADDIS‐ ON, S.; Int.
ChemInform Abstract: Light‐Mediated Transformations of Olefins into Alcohols: Reactions of Hydroxyl Radicals with Cycloalkenes.
Authors: SONAWANE H. R. , NANJUNDIAH B. S. , KELKAR R. G.
Published: May 2016

The title reaction represents a convenient methodology of converting cycloalkenes such as (I), (III), (VII) and (X) into sec. alcohols.
ChemInform Abstract: Metallorganic Synthesis in an Aqueous Medium: Synthesis of Vinylallylcarbinols.
Authors: MISRYUKOV E. A. , KORSHEVETS I. K.
Published: May 2016

The vinylallylcarbinols (III) are prepared from the allylic compounds (II) and the α,β‐unsaturated aldehydes (I) with zinc in the presence of a weakly acidic activator in an aqueous medium.
ChemInform Abstract: Rhodium‐Catalyzed C‐C Coupling of 1,3‐Dienes with 3‐Alkenoic Acids.
Authors: SALERNO G. , GIGLIOTTI F. , CHIUSOLI G. P.
Published: May 2016

The rhodium‐catalyzed reaction of the 1,3‐dienes (I) and (V) with the 3‐alkenoic acids (II) and (VIII) produces mixtures of the 3,6‐dienoic acids (III) and (IV), (VI) and (VII), or (IX) and (X), depending on the steric effects of the reactants.
ChemInform Abstract: Synthesis of “D‐Isothreonine” and “L‐Alloisothreonine” Starting from L‐Alanine.
Authors: WOLF J.‐P. , PFANDER H.
Published: May 2016

L‐Alanine (I) is converted to the isomeric oxazolidinones (II) and (III) by a known procedure.
ChemInform Abstract: Chemistry of α‐Chloroethyl Carbonates and Carbamates Nucleophilic Substitution.
Authors: RIONDEL A. , CAUBERE P. , SENET J.‐P. , LECOLIER S.
Published: May 2016

The α‐chloroethyl carbonates or carbamates (I) react with the rhodanides (II) in the presence of or without phase‐transfer catalysts, yielding the isomeric substitution products (III) and (IV).
ChemInform Abstract: Investigations in the Cyclobutanedicarboxylic Acids Series. Part 9. α‐Truxillic Bis(dialkylaminoalkylamide) Salts Possessing Curare‐Like Activity.
Authors: ARENDARUK A. P. , ABRAMOVA H. A. , SKOLDINOV A. P. , KHARKEVICH D. A.
Published: May 2016

α‐Truxillic dichloride (I) and the amines (II) yield the bis(dialkylaminoalkylamides) (III), from which hydrochlorides and hydrobromides as well as salts with sulfuric, maleic, and fumaric acids are prepared.
ChemInform Abstract: Direct Formation of a Tricyclic Cycloheptanone‐Containing System by Enolate Condensation with a Cyclopropanone Derivative.
Authors: CAREY J. T. , KNORS C. , HELQUIST P.
Published: May 2016

The annellated cycloheptanone (V) can be prepared in a one‐pot reaction from the hemiacetal (I) as given in the scheme.
ChemInform Abstract: Phenyl‐Capped Octaaniline (COA): An Excellent Model for Polyaniline.
Authors: LU F.‐L. , WUDL F. , NOWAK M. , HEEGER A. J.
Published: May 2016

It is reported that the title compound (III) can be characterized in three stable oxidation states: the reduced, COA (leuco, B7) (III), the fully oxidized (tetraquinone imine, "TQI", B3Q4, old nomenclature: "pernigraniline"), and the intermediate oxidation state, B5Q2 ("emeraldine") (B: benzenoid, Q: quinonoid phenyl group within the brackets of (III)).
ChemInform Abstract: Fluorosulfonation. Insertion of Sulfur Trioxide into Allylic C‐F Bonds.
Authors: KRESPAN C. G. , DIXON D. A.
Published: May 2016

The fluoro olefins (I), (IV), (VI), and (IX) react with SO3 in the presence of BF3 or trimethylborate to give products such as (II), (V), (VII), and (X), resulting from insertion into allylic C‐F bonds.
ChemInform Abstract: Synthesis, Antibacterial and Antifungal Activities of Some New Derivatives of Benzothiazole, 1,4‐Benzothiazine and 1,5‐Benzothiazepine.
Authors: GRANDOLINI G. , AMBROGI V. , ROSSI C. , TIRALTI M. C. , TUTTOBELLO L.
Published: May 2016

The diamino nitrobenzene (I) is converted first to the thiocyanate (III) and then to the sodium salt (V), both of which are cyclized to give the benzothiazoles (VIa)‐(VIc).
ChemInform Abstract: Pseudohalogeno Metal Compounds. Part 65. Synthesis of Tetrazoles and Triazoles via 1,3‐Dipolar Cycloaddition to the Azido Ligands of Polymeric Cobalt(III) and Palladium(II) Complexes. Synthesis and Structure of 5‐Trichloromethyltetrazole.
Authors: GEISENBERGER J. , ERBE J. , HEIDRICH J. , NAGEL U. , BECK W.
Published: May 2016

The cycloaddition of nitriles (II) and (V) or the alkyne (VII) with the azide function of the polymeric Co complex (Ia) affords Co‐heterocycle complexes of type (III), giving the free tetrazoles (IV), (VI) and triazole (VIII) on cleavage with HCl.
ChemInform Abstract: Convenient Synthesis of 3‐Aminocoumarin Derivatives by the Condensation of 1,4‐Diacetyl‐ or 3‐Substituent‐2,5‐piperazinediones with Various Salicylaldehyde Derivatives.
Authors: SHIN C. , NAKAJIMA Y. , HAGA T. , SATO Y.
Published: May 2016

The condensation of the piperazinedione (I) with the salicylaldehyde derivatives (II) yields the arylmethylene piperazinediones (III) and the coumarin derivatives (IV); the former are readily converted to the latter by photolysis.
ChemInform Abstract: Synthesis of 2‐Alkoxy‐3‐cyano‐(2H)chromenes.
Authors: AUZUO G. , RENE L.
Published: May 2016

The 2‐morpholino‐3‐cyano‐2H‐chromenes (I) react with the alcohols (II) to give the 2‐alkoxychromenes (III).
ChemInform Abstract: Synthesis of the Chromophore of Rubrolone.
Authors: KELLY T. R. , ECHAVARREN A. , WHITING A. , WEIBEL F. R. , MIKI Y.
Published: May 2016

The synthesis of the chromophore (X) of rubrolone (XI) is described.
ChemInform Abstract: Synthesis and Anticonvulsant Activity of 2‐Alkyl‐3‐amino‐4(3H)‐quinazolinones.
Authors: KORNET M. J.
Published: May 2016

The title compounds (III) are screened for their anticonvulsant activity and neurotoxicity.
ChemInform Abstract: 3,6‐Dihydro‐1,5‐dimethyl‐3‐phenyl‐6‐thioxo‐1‐pyrimidinium‐4‐olate. ‐ Synthesis and Cycloaddition Reactions to Electron‐Rich CC‐Multiple Bond Systems.
Authors: GOTTHARDT H. , BLUM J.
Published: May 2016

1,4‐Dipolar cycloaddition of the enolate (I) with the compounds (II) yields the products (III).
ChemInform Abstract: Decarboxylation of Phthalidecarboxylic Acids in the Presence of Imines. A Facile Route to Isoindolo(1,2‐b)(3)benzazepin‐5‐ones and Phthalideisoquinolines.
Authors: CHIEFARI J. , JANOWSKI W. , PRAGER R.
Published: May 2016

The phthalidecarboxylic acids (I) react with the imines (II) or (IV) under decarboxylation to give the adducts (III) or (V).
ChemInform Abstract: Studies on the Synthesis of Gloeosporone. Synthesis of the Proposed 2,8‐Disubstituted Oxocane Structure.
Authors: CARLING R. W. , HOLMES A. B.
Published: May 2016

The cis‐carbinol (I) is converted to cis‐(III) by trifluoromethylsulfonation, substitution and deprotection.
ChemInform Abstract: Diethyl and Diisopropyl Phosphite Complexes of Lanthanoid(III) Chlorides.
Authors: KAPOOR P. N. , SARASWATI R.
Published: May 2016

Lanthanoid chlorides form the title complexes (I) (no yields given) upon reaction with diethyl or diisopropyl phosphite in excess in dry EtOH or iPrOH (reflux, 7‐8 h).
ChemInform Abstract: Siloxy‐Zirconium Chemistry. Part 1. Reaction of Zr‐C σ‐Bonds with R3SiOH and the Crystal Structure of (1,2‐Dimethoxyethane)bis(triphenylsiloxy)dichlorozirconium(IV), (DME)ZrCl2(OSiPh3)2.
Authors: BABAIAN E. A. , HRNCIR D. C. , BOTT S. G. , ATWOOD J. L.
Published: May 2016

With the goal to prepare a Zr compound containing a crown ether, siloxy ligands and alkyl groups, the reactions of (I) with silanols to establish the conditions for silanol cleavage of Zr‐C σ‐bonds are examined.
ChemInform Abstract: The Reactivity of the (Mn2(μ‐O)(μ‐CH3CO2)2)2+ Core. The Crystal Structures of (LMn(N3)3) and (L′Mn(S4)(H2O)) (L: 1,4,7‐Triazacyclononane, L′ = N,N′,N′′‐Trimethyl‐1,4,7‐triazacyclononane).
Authors: WIEGHARDT K. , BOSSEK U. , NUBER B. , WEISS J.
Published: May 2016

On addition of solid NaN3 or NaNCS to an ethanolic solution of (I) at 20 °C the complexes (II) are prepared.
ChemInform Abstract: Novel Photochemical Reaction in the Cymantrene Derivative Series.
Authors: BARSEGOVA M. N. , LOIM N. M. , BARANETSKAYA N. K. , SETKINA V. N.
Published: May 2016

The isomeric complexes (III) and (IV) are obtained together with the expected compound (II) during the photochemical substitution reaction of a CO ligand by triphenylphosphine in the diphenylphosphinocymantrene (I).
ChemInform Abstract: Formation of Furans and 1‐Rhena‐4‐oxacyclohexa‐2,5‐diene Compounds from Reactions of Cp*ReO3 (Cp*: η5‐C5Me5) with PPh3 in Alkynes.
Authors: DE BOER E. J. M. , DE WITH J. , ORPEN A. G.
Published: May 2016

Treatment of the Re trioxide (I) with triphenylphosphine in pure alkynes for a short time at room temp. results in the formation of the Re monooxide adducts (II).
ChemInform Abstract: The Copper(II) Complexes of 1‐Allyl‐3‐(o‐, m‐ and p‐carboxyphenyl)‐2‐thiourea.
Authors: NEUBAUER L. J. , GREENAWAY F. T.
Published: May 2016

The reaction of Cu(ClO4)2 with (Ia) in EtOH or H2O and with (Ib) and (Ic) in H2O yields the title complexes (II)‐(V), which are characterized by elemental analysis, IR, EPR and electronic spectral studies.
ChemInform Abstract: Synthesis of β‐Benzyl N‐(tert‐Butoxycarbonyl)‐L‐erythro‐β‐(benzyloxy)aspartate from (R,R)‐(+)‐Tartaric Acid.
Authors: HANSSON T. G. , KIHLBERG J. O.
Published: May 2016

The benzyl ester (Ia), derived from (R,R)‐tartaric acid, is monobenzylated to give (Ib) and subsequently transformed into the amino derivative (IIb) via (Ic) and (IIa).
ChemInform Abstract: Nucleotides. Part 26. New Synthesis of 9‐(β‐D‐Ribofuranosyl)uric Acid and Its 5′‐Monophosphate.
Authors: SCHULZ B. S. , PFLEIDERER W.
Published: May 2016

The title compound (X) is synthesized starting from guanosine (Ia) via the successive intermediates shown in the scheme.
ChemInform Abstract: Syntheses and Hydrolysis Reactions of Some 2,3′‐(Substituted‐Imino)‐1‐ (3′‐deoxy‐β‐D‐lyxofuranosyl)uracils.
Authors: MINAMOTO K. , TANAKA T. , AZUMA K. , SUZUKI N. , EGUCHI S. , KADOYA S. , HIROTA T.
Published: May 2016

Reaction of the 2,2'‐anhydrouracil derivative (I) with the amines (II) yields the 2,3'‐iminouracils (III) which are debenzoylated to give (IV).
ChemInform Abstract: Tetrahydropyran as an Efficient Alcohol Protecting Group for the Synthesis of Penems: Synthesis of Sch 34343.
Authors: GALA D. , STEINMAN M. , JARET R. S.
Published: May 2016

The azetidinone (I) is converted to the allylic ester (III).
Rheological and thermal properties of novel surfactant‐polymer systems for EOR applications
Authors: Malik Izhar A. , Al‐Mubaiyedh Usamah A. , Sultan Abdullah S. , Kamal Muhammad Shahzad , Hussein Ibnelwaleed A.
Published: May 2016

In this work, two surfactant‐polymer (SP) systems were evaluated for enhanced oil recovery applications. The first SP system contained partially hydrolyzed polyacrylamide and alkyl polyethylene glycol ether‐based non‐ionic surfactant. The second SP system consisted of the same polymer and alcohol propoxylate sulphate‐based anionic surfactant. Rheology, thermal stability, interfacial tension (IFT), and core flooding experiments were performed to evaluate the SP systems at different temperatures, surfactant concentrations, and salt concentrations. The anionic surfactant reduced the viscosity of the polymer. However, the effect of the non‐ionic surfactant on the rheological properties was not significant. The non‐ionic surfactant was found to be stable at 80 °C while the structural changes were identified in the anionic surfactant after aging. IFT values of both surfactants were measured at various temperatures and salinities. Due to poor thermal stability and IFT increasing with temperature, the SP system containing the propoxylated anionic surfactant is recommended for applications in low‐temperature reservoirs only. However, the SP system containing the ethoxylated non‐ionic surfactant showed promising results at high‐temperature and high‐salinity conditions and 26 % additional oil recovery was obtained.
Evaluation of the effectiveness of adding androgen deprivation to modern dose‐escalated radiotherapy for men with favorable intermediate‐risk prostate cancer
Authors: Falchook Aaron D. , Basak Ramsankar , Mohiuddin Jahan J. , Chen Ronald C.
Published: May 2016

BACKGROUND

Randomized trials have shown that androgen‐deprivation therapy (ADT) improves survival for men with intermediate‐risk prostate cancer treated with radiotherapy (RT). The benefit of ADT to patients with favorable intermediate‐risk prostate cancer treated with modern dose‐escalated RT is unknown. This study evaluated the effectiveness of ADT on survival of men with favorable intermediate‐risk prostate cancer treated with dose‐escalated RT.

METHODS

This study was a retrospective cohort analysis of men with favorable intermediate‐risk prostate cancer from 2004 to 2007 in the National Cancer Data Base. Favorable intermediate‐risk disease was defined as 1 adverse risk factor (prostate‐specific antigen level of 10‐20 ng/mL or Gleason score of 7) and clinical T1/T2 prostate cancer. All patients were treated with primary dose‐escalated RT (≥75.6 Gy or RT with a brachytherapy boost). Overall survival was analyzed with propensity score adjustment and Cox multivariate modeling.

RESULTS

The study included 18,598 patients. The use of ADT decreased from 43.5% in 2004 to 39.5% in 2007. The propensity score–adjusted survival analysis demonstrated similar 8‐year overall survival for men treated with dose‐escalated RT and ADT and men treated with RT alone (77.7% vs 78.4%). ADT was not associated with improved survival in any age or comorbidity subgroup. In a sensitivity analysis using Cox multivariate modeling, the receipt of ADT was not associated with overall survival (hazard ratio, 0.99; 95% confidence interval, 0.91‐1.07; P = .768).

CONCLUSIONS

Adding ADT to modern dose‐escalated RT was not associated with improved survival for patients with favorable intermediate‐risk prostate cancer. The applicability of the survival benefit seen in older trials to modern patients is unclear. Because of the morbidity associated with ADT, dose‐escalated RT alone for patients with favorable intermediate‐risk prostate cancer may be a reasonable option. Cancer 2016;122:2341–2349. © 2016 American Cancer Society.
Open‐label, multicenter, phase 1 study of alisertib (MLN8237), an aurora A kinase inhibitor, with docetaxel in patients with solid tumors
Authors: Graff Julie N. , Higano Celestia S. , Hahn Noah M. , Taylor Matthew H. , Zhang Bin , Zhou Xiaofei , Venkatakrishnan Karthik , Leonard E. Jane , Sarantopoulos John
Published: May 2016

BACKGROUND

This study was designed to determine the safety, tolerability, and pharmacokinetics (PK) of alisertib (MLN8237) in combination with docetaxel and to identify a recommended dose for the combination.

METHODS

Adults with metastatic cancer were treated on 21‐day cycles with alisertib (10, 20, 30, or 40 mg) twice daily on days 1 to 7 or days 1 to 5 and with docetaxel (75 or 60 mg/m2) on day 1. The primary objectives were to assess the safety and tolerability of the combination and to determine the recommended phase 2 dose (RP2D) for future studies. Secondary objectives included an efficacy assessment and PK analyses of docetaxel and alisertib.

RESULTS

Forty‐one patients participated. Eight dose levels were explored with various doses of alisertib and docetaxel. The dose‐limiting toxicities were neutropenic fever, neutropenia without fever, stomatitis, and urinary tract infection. The RP2D of this combination was 20 mg of alisertib twice daily on days 1 to 7 and intravenous docetaxel at 75 mg/m2 on day 1 in 21‐day cycles. Eight of the 28 patients (29%) who were efficacy‐evaluable had objective responses. These included 1 complete response in a patient with bladder cancer, 6 partial responses in patients with castration‐resistant prostate cancer, and 1 partial response in a patient with angiosarcoma. Concomitant administration of alisertib did not produce any clinically meaningful change in docetaxel PK.

CONCLUSIONS

Alisertib at 20 mg twice daily on days 1 to 7 with intravenous docetaxel at 75 mg/m2 on day 1 in a 21‐day cycle was well tolerated, and the combination demonstrated antitumor activity. Cancer 2016;122:2524–33. © 2016 American Cancer Society.
Synthesis of Monodisperse Palladium Nanoclusters Using Metal–Organic Frameworks as Sacrificial Templates
Authors: Li Xinle , Goh Tian Wei , Xiao Chaoxian , Stanton Alexandria L. D. , Pei Yuchen , Jain Prashant K. , Huang Wenyu
Published: May 2016

An interfacial etching approach was developed for the synthesis of monodisperse and ultrasmall thiolated palladium nanoclusters (Pd NCs) using Zr‐UiO‐66‐NH2 metal–organic frameworks (MOFs) as sacrificial templates. The Pd NCs were originally synthesized inside the cavities of the MOFs (Pd@UiO‐66‐NH2). The Pd NCs released from the MOFs have a strikingly small size with narrow distribution (1.1±0.1 nm), amounting to a cluster size of ca. 40 Pd atoms. The 1H NMR spectrum indicates that thiol is the only capping agent for these Pd NCs. We derived the composition of the thiolated Pd NCs using thermogravimetric analysis (TGA) and inductively coupled plasma mass spectrometry (ICP‐MS) analysis. Moreover, the Pd NCs size can be tuned by using MOF templates with different cavity sizes. The thiolated Pd NCs are catalytically active in a model Suzuki–Miyaura coupling reaction.
A Twofold Interpenetrated Metal–Organic Framework with High Performance in Selective Separation of C2H2/CH4
Authors: Alduhaish Osamah , Wang Hailong , Li Bin , Hu Tong‐Liang , Arman Hadi D. , Alfooty Khalid , Chen Banglin
Published: May 2016

A twofold interpenetrated metal–organic framework, PMOF‐3, composed of four kinds of polyhedra exhibits the highest selectivity of 157 for C2H2/CH4 separation at 296 K and 1 atm owing to the synergistic effect of the open metal sites, C≡C triple bonds, and microporous structure.
Organizational dynamic embeddedness and external shocks: The impact of financial and recession crises in strategic networks of the global pharmaceutical industry
Authors: Shijaku Elio , Larraza‐Kintana Martin , Urtasun‐Alonso Ainhoa
Published: May 2016

We analyze the global pharmaceutical industry network using a unique database that covers strategic transactions (i.e., alliance, financing and acquisition collaborations) for the top 90 global pharmaceutical firms and their ego‐network partnerships totaling 4735 members during 1991–2012. The article explores insights on dynamic embeddedness analysis under network perturbations by exploring core and full networks' behavior during the global financial crisis of 2007–2008 and the subsequent global and Eurozone recessions of 2009–2012. We introduce and test literature grounded hypotheses as well as report network visualizations and nonparametric tests that reveal important discrepancies in both network types before and after the financial crisis offset. We observe that firms in core and full networks behave differently, with smaller top pharmaceutical firms of core networks particularly being affected by the crises, potentially due to a collaboration reduction with bigger top pharmaceuticals. On the other hand, big pharmaceuticals in full networks maintain their centrality position as a possible consequence of their strategic collaborations not only with other similarly sized firms but also due to their connections with subsidiaries and other private entities present in the total sample. Our results confirm the significant dynamicity reduction during financial crisis and recession periods for core and full networks, and highlight the importance that exogenous factors as well as network types play in centrality‐based dynamic longitudinal network analysis. © 2016 Wiley Periodicals, Inc. Complexity 21: 602–621, 2016
Body image and eating behavior in young adults born preterm
Authors: Matinolli Hanna‐Maria , Männistö Satu , Sipola‐Leppänen Marika , Tikanmäki Marjaana , Heinonen Kati , Lahti Jari , Lahti Marius , Wehkalampi Karoliina , Järvelin Marjo‐Riitta , Andersson Sture , Lano Aulikki , Vartia Timo , Wolke Dieter , Eriksson Johan G , Vääräsmäki Marja , Räikkönen Katri , Kajantie Eero
Published: May 2016

Objective

Previous studies have suggested that people born preterm have increased rates of eating disorders (ED). However, a recent study suggested lower levels of ED‐related symptoms in the extreme group of adults born preterm with very low birth weight (<1,500 g). We examined symptoms related to EDs in adults born early (<34 weeks of gestational age) or late (34 to <37 weeks of gestational age) preterm.

Methods

We studied young adults (mean age 24.1 years) from two birth cohorts: ESTER (Northern Finland 1985–1989) and AYLS (Uusimaa, Finland, 1985–1986). Of the participants, 185 were born early preterm, 348 late preterm, and 637 were term‐born controls (N = 1,170). They completed three subscales of the Eating Disorder Inventory (EDI)−2, including Drive for Thinness (DT), Body Dissatisfaction (BD), and Bulimia (B). Group differences were examined by linear regression.

Results

Young women born early preterm scored 4.1 points (95% CI −8.0, −0.2, P =.04) lower in summed EDI subscale scores than women born at term, when adjusted for age and cohort. This difference was observed also in DT and BD but not for B subscales. The differences persisted after adjustments for current, pre‐ and neonatal characteristics. We did not observe differences in EDI scores among men or women born late preterm when compared to controls.

Discussion

Women born early preterm have significantly fewer symptoms related to EDs in early adulthood when compared to their peers born at term, which may protect from developing an ED. © 2016 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:572–580)