bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors Associated with Long-Term COVID-19: An Observational Cross-Sectional Study in Indonesia
Authors: Puspitasari Arina Dery , Ardianto Nanda , Aina Lily , Kundiman Eunice Marlene Sicilia , Satryo Fatimatuz Zahra Oviary , Rachman Melinda Putri Amelia , Meiliani Fauzul , Hapsari Pharmasinta Putri , Zulkarnain Bambang Subakti , Rosyid Alfian Nur , Budiarti Tamara Nur , Wardhani Brigitta Dhyah Kunthi
Published: July 2022

Long-term COVID-19 could occur in COVID-19 patients, affecting the patient's quality of life, and becoming a  problem for public health. However, information is rarely on factors associated with the occurrence of long COVID-19 cases. This study analyzed factors associated with long-term COVID-19. The study was an observational cross-sectional, conducted in August 2021. The data were collected through a Google form questionnaire distributed to COVID-19 survivors in Indonesian. They must be aged more than 17 years to meet the inclusion criteria, while those with incomplete data were excluded. The data were processed by using SPSS 21 with an ordinal regression test in which an alpha level was 5%. As many as 101 from 16 men (15.8%) and 85 women (84.2%) were obtained. Comorbid status (p-value = 0.001) and duration of treatment (p-value = 0.034 and 0.015) had a significant association with the occurrence of long-term COVID-19. Meanwhile, age, gender, occupation, type of care, and vaccination status were not likely associated with long-term COVID-19. COVID-19 patients with comorbidity and a long duration of treatment are more likely to experience long-term COVID-19.

Keywords: COVID-19, long-term COVID-19, factor, public health
Design, Optimization and Evaluation of Etoricoxib Castor Oil Emulgel for acute gout therapy
Authors: Sharma Khushboo , Rai Janki Prasad , Somkuvar Sushma , Singhai Akhlesh Kumar
Published: July 2022

Etoricoxibis is a non-steroidal anti-inflammatory drug which showed anti-inflammatory, analgestic and antipyretic activities. Etoricxib is indicates in the management of Osteoarthritis, Rheumatoid and Acute gout. The major drawback of topical dosage form is dissolution and diffusion of drug in the delivery of hydrophobic drugs, and permeation through stratum corneum is for hydrophilic drugs, thus, to be referred as emulgels. In emulgel formulations, oil-in-water and water-in-oil emulsions are commonly utilised as vehicles to deliver different hydrophilic and hydrophobic medications to the skin. They're also good in dissolving drugs and penetrating skin. Oil-in-water emulsions are mostly used as medication bases that may be washed away. The proposed research project intends to create an emulgel containing the analgesic drug Etoricoxib. The created emulgel containing etoricoxib medicines has a topical route that is more permeable, regulated, and localised. The analytical procedure of etoricoxib medicine was assessed using described UV spectrophotometric techniques in pH Phosphate buffer 6.8 and exhibited good linearity of data, as demonstrated by correlation coefficients greater than 0.998. For organoleptic characteristics, flow qualities, and partitioning, preformulation experiments were employed. All result of preformulation study was satisfactory and drug was examined visually for their feeling after application on skin, color intensity, pH determination, consistency and extrudability determination. The result concluded that ETEG4 was best formulation. This formulation ETEG4 was prepared emulgel Carbopol 940 (2g), PVP, castor oil base. The drug release profile and release kinetics are two important characteristics of the dosage forms, which play an important role for describing dissolution profile of dosage form. The dissolution data was obtained and ETEG4 showed supercase II transport mechanism.

Keywords: Etorcoxib, Castor Oil, Emulgel, Osteoarthritis, Rheumatoid, Acute gout
Design, Synthesis, Pharmacological Evaluation and DFT Investigation of New Bioactive Unsymmetrical Bi-Functional Ligand
Authors: Najar Adel M. , Omar Ruwida M.K. , Bobtaina Eman , Jabber Salem , Mohamed Najwa , Aeyad Tahani , Tawati Salha M. , Khalifa Aliaa M. M.
Published: July 2022

Compounds with more than one bioactive motif become of great interest. In this regard, a new tridentate 1,2-unsymmetrical ligand consists of flexible and rigid bioactive arms spaced by benzene ring in an ortho position designed to form a bifunctional molecule. The 2-((3-(pyridin-2-yl)-1H-pyrazol-1-yl)methyl)benzonitrile (PPMB) synthesized under phase transfer reaction and characterized using 1H-NMR and mass spectroscopy and studied as potent kinase inhibitors. Theoretically, the molecule structure was investigated at the B3LYP/6-311++G(d,p) level of theory in the gas phase and revealed that all bond lengths and bond angles within the accepted limit. The frontier molecular orbitals (FMO) energies (HOMO and LUMO), energy gap, dipole moment, chemical softness and chemical hardness were calculated. Pharmacologically, the ligand activity was investigated in silico using SWISS ADME. Furthermore, the compound was docked into the transforming growth factor (TGF) beta type I receptor kinase active site to evaluate the ability of ligand as a kinase inhibitor.

Keywords: DFT, pyrazolyl-pyridine, physiochemical, properties molecular docking, bioactive molecules, unsymmetrical ligands
Multi-Functional Therapeutic Active Extract of Marine Asterias rubens against Tooth Decay Pathogen
Authors: Vijayalakshmi S. , Mohankumar A.
Published: July 2022

Today, childhood caries is main health related disease it affects many schooling children in many countries especially developed by lactic acid bacteria. So in this present the isolating the 50 lactic acid bacteria from different decay affected children’s in Fen Dental Clinic, Tirupur Dt. The emerging bacteria LAB confirmed by phenotype and genotype characterization. After, the pathogen screened for the production of biofilm for to check the resistant mechanism of the Lactobacillus acidophilus. In this study the MTLA1-50 isolates produced strong biofilm were confirmed for the Lactobacillus acidophilus carrying resistant capability. In particularly, the maximum strong biofilm producing strains MTLA32 and MTLA50 followed by other isolates. Due to pre-dominant resistant activity immediately need innovative drug to eliminate biofilm. Currently star fish extract play a vital role in eliminating the bacterial biofilm for this motive in this study chosen the star fish extract in the concentration of 50, 100, 150µl was performed and executed by well diffusion techniques. The results showed the strain No. MTLA32 and MTLA 50 got the maximum zone of inhibition at 150µl (52mm and 38mm) of extract. Hence this research paper proved the star fish extract has a powerful anti-therapeutic medicine mechanism to treat the dental pathogen.

Keywords: Star Fish Extract, Dental Caries, Biofilm Production.
Anti-Inflammatory Properties of Quercetin: A Review
Authors: Nweze Chibuzo Carole , Tseaa Wandoo , Ekpe Ini Patrick
Published: July 2022

Quercetin, one of the most taken flavonoid with diet, belongs to the family of flavonols. Quercetin occurs as a glycoside or as an aglycone and is gotten from various dietary sources such as apples, berries, onions, kale. Quercetin is being reviewed based on its bioavailability, metabolism and anti-inflammatory properties. Inflammation is the body's immune response to an irritant; this could be a pathogen or foreign object. An inflammatory response is either acute or chronic depending on the duration of inflammation and prolonged inflammatory response can lead to various diseases that are harmful to the body. Studies have shown that quercetin exerts good anti-inflammatory, antioxidant and anti-allergic activity by acting on leukocytes, targeting signaling kinases as well as membrane proteins crucial for an inflammatory response and acts as a scavenger of free radicals. Quercetin also down regulates the expression of pro-inflammatory factor while up regulating the expression of anti-inflammatory factor and this aids in maintaining homeostasis. Although poorly bioavailable due to its rapid metabolism, quercetin is an effective modulator of inflammation.

Keywords: Quercetin, inflammation, antioxidants, flavonols, free-radicals
Review: Hydrotropy as Prominent Approach for Enhancement of Aqueous Solubility of Drugs
Authors: Kazi Maseera Rizwan , Gandhi Sanket , Desai Shubham V. , Barse Rohan , Jagtap Vijay
Published: July 2022

Solubility is crucial element to achieve the desired drug absorption in the total pharmacological response. Low water solubility can considerably limit the medication efficacy, and to improve aqueous solubility, a variety of approaches are employed. The capacity which increases water solubility for particular drug can thus be a useful tool for enhancing efficiency and/or decreasing negative effects. This is true for parental administered, topically applied and orally consumed solutions. It is a difficult work for researchers and pharmaceutical scientist to use solubility features in bioavailability, pharmacological effect and solubility enhancement of diverse weakly soluble substance. Hydrotropy is one of the strategies for increasing solubility. The purpose of this paper is to examine the hydrotropy Solubilization technique and to highlight the mechanism and different prospective of this method.

Keywords: Hydrotropy, mechanism, formation of hydrotropes, Solubility
COVID-19: New Challenge in 21st Century
Authors: Tamboli Siddhesh Sunil , Surwade A.B. , Mahale K.J. , Darekar A.B. , Wagh L.K. , Ugale P.G.
Published: July 2022

COVID-19 pandemic turned into the proven existence-threatening virus in-line with World Health Organization (WHO) has declared a public health emergency of International Concerned and our healthcare system found a challenge to save human civilization. This evaluation gives a brief idea of COVID-19 epidemiology, pathophysiology, treatment, and prevention of COVID-19. Exclusive drugs like Dexamethasone and Remdesivir were found effective to treat the virus was covered in this review article. Pathophysiology of virus in the body of diabetes and cancer patients, there mechanism of action and risk involved in that patients were studied. This review turned to conduct on data found in science direct, various information sources on the internet and different review articles were studied. The major objective is to provide a brief overview of this disease, study infectious virus effect on   human beings proves to be an existence-threat to the world population and brief overview of COVID-19 was covered in this review article.

Keywords: SARS-CoV-2, MERS, Vaccine, Dexamethasone, Remdesivir.
In vivo assessment of acute and subchronic toxicity of hydroethanolic extract of Ximenia americana L. (Olacaceae) stem bark
Authors: TOGBOSSI Lucie Akouélévi , Lawson-Evi Povi , Atchou Nestor K. , Motto Enam A. , Diallo A. , Eklu-Gadegbeku Kwashie , Aklikokou Kodjo
Published: July 2022

Many studies have confirmed the traditional use of Ximenia americana (Olacaceae). Its different parts, leaf, fruit, roots, stem bark and root bark have showed pharmacological potentials. X. americana is a plant which possessed antibacterial, antidiabetic, antiviral and anticancer properties. The present study was undertaken to evaluate the oral acute and subchronic toxicity of hydroethanolic extract of X. americana stem bark on Sprague Dawley rats. In acute test, female rats were administrated once 5000 mg/kg and observed during 14 days for determination of toxicity signs. For the subchronic toxicity the extract (500 mg/kg and 1000 mg/kg) was administrated daily to both sexes of rats during 28 days. Control rats were administrated distilled water. Animals were observed, food and water consumption, mortality were monitoring during experiment period. Body weight, organs relative weight, hematological and biochemical parameters and histopathological changes were conducted at the end of treatment. Acute toxicity test revealed no adverse effects and no mortality. Extract administration during 28 days does not cause any behavioral change, change in body and organs relative weight and mortality. No significant variation was observed in hematological, biochemical parameters between treatment and control groups. No remarkable structural change was found in organs. However, triglycerides show significant variation in both sexes but this variation was not dose dependent. Results suggested that the LD50 of hydroethanolic extract of X. americana stem bark is higher than 5000 mg/kg and extract administration at 1000 mg/kg during 28 days does not cause toxicity in Sprague Dawley rats.

Keywords: Ximenia americana; stem bark; acute toxicity; subacute toxicity; hematological parameters; biochemical analysis.
Female Obesity: A Probable Cause of Infertility
Authors: Nair Nayana B , Skaria Minnu , Sambath Kumar R.
Published: July 2022

Obesity, a serious health problem, is a widespread affliction among women of reproductive age. Obesity and overweight refer to an abnormal and excessive fat deposition that has a negative impact on the body's health. Obesity causes a slew of issues, including social, psychological, demographic, and health issues. It has been associated to elevated health risks like diabetes, hypertension, coronary heart disease, and osteoarthritis, as well as numerous cancers like endometrial, breast, and colon cancers. Hyperandrogenemia is caused by insulin resistance and hyperinsulinemia in obese women. The levels of sex hormone-binding globulin (SHBG) are lower, but leptin levels are higher. Impaired ovulatory function and, as a result, reproductive health could be explained by these changes. Obese women have a reduced probability of giving birth to a healthy infant due to lower implantation and pregnancy rates, greater miscarriage rates, and increased maternal and fetal problems throughout pregnancy. In these people, losing weight has a positive impact on their reproductive outcomes.

Keywords: Obesity, Hyperandrogenemia, Sex hormone-binding globulin (SHBG).
Pengaruh Citra Merek Dan Kualitas Produk Terhadap Kepoutusan Pembelian Minuman Teh Dalam Kemasan Siap Saji Teh Botol Sosro
Authors: Prasetya Ma’ruf Akbar , Harwani Yuli
Published: July 2022

This study aims to to examine and analyze the influence of image brands and product quality of the decision the purchase drink tea in packs brand tea bottles sosro in indonesia. (a case study on the consumer they get milk to drink a small plastic bottle full of tea leaves are set sosro in kecamatan kebon jeruk , west jakarta). Technique the sample collection in this research the convenience of sampling. Respondents in this research as many as 100 respondents from the customers tea in sub-district kebon jeruk sosro bottle , west jakarta. It is an approach that in use on of this research is structural equation a model (shem) with a tool it is anticipated that analysis smart-pls.The results of the test which has been these chareges in the future after do our tests structural models such as linking banks/efforts whatever survives this test a hypothesis (inner religion a model) shows that brand shots would take off and the product quality and increase of the decision of pt indofood acquired misp shares. Variable image brand have had a positive impact and significant of the decision the purchase. The product quality variable have had a positive impact and significant of the decision of the purchase.
Sustainable Palm Oil: What Drives it and Why Aren’t We There Yet?
Authors: Nor Ahmad Saidatul Nurul Hidayah , Amran Azlan , A.K. Siti-Nabiha , Abdul Rahman Rusniza
Published: July 2022

Manuscript type: Research paper Research aims: This study explores the institutional pressure and motivation that drives Malaysian palm oil companies to embark on sustainability practices, and uncovers the impediments of substantive change in producing truly sustainable palm oil. Design/Methodology/Approach: A case study methodology was employed, gathering primary and secondary data through semistructured interviews with the company’s personnel and external stakeholders, through informal conversations and group discussions with company workers, document analyses, and observations. The neo-institutional and legitimacy theory were used as the primary lens to explain the study findings. Research findings: The results indicate that both external pressures and internal issues have forced the company to engage in sustainability practices – primarily through certification. Unlike the independent stakeholder pressure found in previous studies, a chain reaction of pressures was found from NGOs and competitors to multinational buyers, whom in turn put pressure on the case company, thus jeopardising their financial bottom lines. Regulatory pressures, conforming to the industry norms, wooing host country’s government, investors, and financiers add to the external motivation. Reputational problems and labour shortages, business case for sustainability, and the philanthropic nature of family-owned firms are the internal elements behind the endeavour. The barrier to change towards sustainability was mainly caused by cost concern, technical difficulties, mindset of workers, unsupportive business environment and impracticalities of safety equipment design. Originality/value: The findings shed light on the inner motive and barriers of change towards producing sustainable palm oil, the understanding of which is vital in driving further substantive changes in the palm oil industry towards sustainable development. Research limitation/Implication: The study was restricted to a single case company in the Malaysian palm oil industry and hence, generalisation of the study findings onto another context should be done in a cautious manner. Keywords: Organisational change, Neo-institutional theory, Legitimacy theory, Palm oil, Sustainability reporting and practice JEL Classification: Q56
Progresivitas Hakim dalam Menentukan Beban Akibat Perceraian Bagi Suami Kepada Istri Pasca Perceraian
Authors: Anwar Alfina Sauqi
Published: July 2022

There are variation of Judges in determining husband’s obligatory burden toward their wives due to divorce because there is no provision which specially regulate every Judges to determine the amount of the sustenance post divorce. this article describe about how the progression of judges in determining the obligatory burden due to divorce for the husband toward their ex wives. this is a literature study which take the source from Directory of Supreme Court Decision in the First, Appeal and Cassation Level. this study will describe about how the judges in Religious Justice Agency especially Supreme Court in making effort to protect women’s rights post divorce. this sutdy will analyze about Judges’ decision which charge the husbands to fulfill their obligation toward their ex wives in the form of Iddah, Madliyyah and Mut’ah living. the next discussion is about  how the judges apply the progressive law through their decision that is, obligation which is charged to the husband in fulfilling their ex wives’ rights post divorce.
 
Hakim dalam menentukan beban terhadap suami kepada istri akibat perceraian bervariatif dan belum ada ketentuan khusus yang mengatur secara rinci bagi hakim dalam menentukan besar kecilnya besaran nafkah pasca perceraian. Artikel ini menguraikan tentang bagaimana progresifitas hakim dalam menetapkan beban akibat perceraian bagi suami terhadap istri yang diceraikan. Tulisan ini bersifat literer yang bersumber dari Direktori Putusan Mahkamah Agung pada Tingkat Pertama, Tingkat banding, dan Tingkat Kasasi. Tulisan ini akan menguraikan tentang bagaimana hakim pada badan Peradilan Agama khususnya Mahkamah Agung dalam melakukan upaya melindungi hak-hak perempuan pasca perceraian. Tulisan ini akan menganalisa tentang putusan hakim yang membebankan suami untuk  memenuhi kewajiban kepada istri berupa pembayaran nafkah iddah, nafkah madliyyah, dan mut’ah. Pembahasan selanjutnya tentang bagaimana hakim telah menerapkan hukum progresif melalui putusannya yaitu, kewajiban yang dibebankan hakim kepada suami dalam hal pemenuhan hak istri pasca perceraian.
Nalar Konstruktif Maqashid Syariah Dalam Studi Hukum Islam (Sebuah Studi Pengantar dalam Ilmu Maqashid Syariah)
Authors: Fahrudin
Published: July 2022

This study is an attempt to explore the discourse of maqashid sharia, as one of the tools of analysis of texts or sources of Islamic law. Like other disciplines, which also try to approach the sacred text with their own reasoning and specialization. During widespread disagreements over various interpretations of a text, the maqashid sharia reasoning approach as one of ijtihad reasoning, has a very urgent position, of course, to reason problems in a unique way. There is no longer a sanction, that by continuing to turn on maqashid reasoning, as one of the important tools in legal formulation, it is a necessity that every juris (mujtahid) must have. By using several main sources on the science of maqashid sharia, this paper tries to present a maqashid perspective across generations, from the classical era to the modern era. Since the era of al Hakim Tirmidhi to Jaser Audah and other contemporary scholars who continue to spread the knowledge of maqashid. The various cases that occurred and covered the life of the mukallaf (legal subject), from the early days of Islam to the present and future generations, became an important orientation in every legal formula that must be presented. This is nothing but to make Shari'a an entity that continues to live across ages. The benefit of the mukallaf, which is an important point in the descent of the Shari'a, must always be a consideration in every legal formulation.
 
Penelitian ini merupakan sebuah upaya untuk menbedah diskursus maqashid syariah, sebagai salah satu pisau analisis (tools of analysis) terhadap teks atau sumber hukum Islam. Sebagaimana disiplin ilmu yang lain, yang juga mencoba mendekati teks suci dengan nalar dan spesialisasinya masing-masing. Di tengah maraknya silang pendapat akan berbagai interpretasi suatu nas, pendekatan nalar maqashid syariah sebagai salah satu nalar ijtihad, memiliki posisi yang sangat urgen, tentunya untuk menalar problematika dengan caranya yang khas. Tidak sanksi lagi, bahwa dengan terus menghidupkan nalar maqashid, sebagai salah satu piranti penting dalam formulasi hukum, menjadi keniscayaan yang harus dimiliki oleh setiap juris (mujtahid). Dengan menggunakan beberapa sumber pokok tentang ilmu maqashid syariah, makalah ini mencoba untuk menghadirkan perspektif maqashid lintas generasi, sejak era klasik sampai era modern. Sejak era al Hakim Tirmidzi sampai Jaser Audah dan ulama kontemporer lain yang terus mengibarkan ilmu maqashid. Beragam kasus yang terjadi dan menyelimuti kehidupan mukallaf (subjek hukum), sejak masa awal Islam sampai generasi kini dan nanti, menjadi orientasi penting dalam setiap formula hukum yang harus dihadirkan. Hal tersebut tidak lain untuk menjadikan syariat sebagai entitas yang terus hidup lintas zaman. Kemaslahatan mukallaf yang menjadi titik poin penting turunnya syariat, harus selalu menjadi pertimbangan dalam setiap formulasi hukum.
Implementasi Akad Mudharabah Peternakan Sapi Menurut Hukum Ekonomi Syariah
Authors: Tohari Chamim
Published: July 2022

This study specifically examines the implementation of the mudharabah contract in the field of cattle husbandry which has been practiced by residents in Addrejo Village, Kanor District, Bojonegoro Regency. This research includes field research because the data is collected directly from the specified research location. The research approach used is a qualitative descriptive research approach. Data collection techniques were carried out in three ways, namely through interviews, observation, and documentation. The data analysis technique was carried out through several stages, namely editing, organizing, analyzing, and finding results or inferences. The results of this study conclude that the implementation of the mudharabah contract on cattle farming in Addrejo Village, Kanor District, Bojonegoro Regency has fulfilled all the pillars and requirements for the validity of the mudharabah contract contained in Sharia Economic Law, and is carried out based on agreement, willingness, and honesty, so that in line with the principles that form the basis of fiqh muamalah. Because of that, the author can confirm that the practice of cooperative mudharabah for cattle carried out by the residents of the Village of Addrejo, Kanor District, Bojonegoro Regency is in accordance with Sharia Economic Law and the Principles of Fiqh Muamalah.
 
Penelitian ini secara khusus mengkaji tentang pelaksanaan akad mudharabah dalam bidang peternakan sapi yang selama ini dipraktikkan oleh para penduduk di Desa Tambahrejo Kecamatan Kanor Kabupaten Bojonegoro. Penelitian ini termasuk penelitian lapangan (field research) karena data dihimpun secara langsung dari lokasi penelitian yang ditentukan. Pendekatan penelitian yang digunakan adalah pendekatan penelitian deskriptif kualitatif. Teknik pengumpulan data dilakukan dengan tiga cara, yaitu melalui wawancara, observasi, dan dokumentasi. Adapun teknik analisis data dilakukan melalui beberapa tahapan, yaitu editing, organizing, analyzing, dan penemuan hasil atau penyimpulan. Hasil penelitian ini menyimpulkan bahwa implementasi akad mudharabah terhadap peternakan sapi di Desa Tambahrejo Kecamatan Kanor Kabupaten Bojonegoro dilakukan telah memenuhi seluruh rukun-rukun dan syarat-syarat keabsahan akad mudharabah yang terdapat dalam Hukum Ekonomi Syariah, dan dilakukan berdasarkan kesepakatan, kerelaan, dan kejujuran, sehingga sejalan dengan prinsip-prinsip yang menjadi landasan dalam fiqh muamalah. Karena itu dapat penulis pastikan bahwa praktik kerja sama mudharabah hewan ternak sapi yang dilakukan warga Desa Tambahrejo Kecamatan Kanor Kabupaten Bojonegoro tersebut telah sesuai dengan Hukum Ekonomi Syariah dan Prinsip-Prinsip Fiqh Muamalah.
Applications of Hypergeometric Functions with Distribution Theory
Authors: singh pooja
Published: July 2022

Hypergeometric functions are generalized from transcendental functions.
The function and series we use in quantitative economics can be
evaluated analytically and expressed in form of hypergeometric function.
In this paper, we introduce application of different class of
hypergeometric functions in number of areas such as economic theory and
econometric. We are applying our outcomes of generalized hypergeometric
function in non linear model and economic theory. Other applications are
also elaborated therein. This paper will prepare the situation where
potential of generalized hypergeometric functions can be utilized in
quantitative economics.
The Use Of Intraoperative Transit Time Flow Measurement Can Reduce Preoperative Myocardial Injury
Authors: Benetti Federico
Published: July 2022

In the work by Zheng Quan MD et al. about the Use of Intraoperative
Transit Time Flow Measurement Can Reduce Preoperative Myocardial Injury
(1), the authors did a retrospective, observational study of the effects
of exposure to the TTFM procedure . Fifty-nine people received TTFM,
while 47 did not. In total, 7 (6.6%) had at least one grafting vessel
obstruction. Only 1 patient where the TTFM was used had an occlusion
graft vs. 6 patients where the TTFM was not used and had postoperative
injury. In 2001, the use of TTFM techniques for assessing the quality of
grafts intraoperatively, on the basis of the presence and volume of flow
were clearly described) In conclusion, the work of Zheng Quan MD et al.
remarks the importance of the use of TTFM to reduce the incidence of
preoperative myocardial injury during off-pump coronary bypass surgery.
support of, in some ways, the recent expert opinion to promote the use
of TTFM
Computational Analyses of the Interactome between TNF and TNFR Superfamilies
Authors: Dhusia Kalyani , Su Zhaoqian , Wu Yinghao
Published: July 2022

Proteins in the tumor necrosis factor (TNF) superfamily (TNFSF) regulate
diverse cellular processes by interacting with their receptors in the
TNF receptor (TNFR) superfamily (TNFRSF). Ligands and receptors in these
two superfamilies form a complicated network of interactions, in which
the same ligand can bind to different receptors and the same receptor
can be shared by different ligands. In order to study these interactions
on a systematic level, a TNFSF-TNFRSF interactome was constructed in
this study by searching the database which consists of both
experimentally measured and computationally predicted protein-protein
interactions (PPIs). The interactome contains a total number of 194
interactions between 18 TNFSF ligands and 29 TNFRSF receptors in human.
We modeled the structure for each ligand-receptor interaction in the
network. Their binding affinities were further computationally estimated
based on modeled structures. Our computational outputs, which are all
publicly accessible, serve as a valuable addition to the currently
limited experimental resources to study TNF-mediated cell signaling.
Sporotrichoid lymphocutaneous pattern in a fish-merchant under immunosuppressant medications: Clues to differential diagnoses
Authors: khadka dhan , acharya ripala , agrawal sudha
Published: July 2022

Sporotrichoid-lymphocutaneous-pattern is classically seen in
sporotrichosis, though also present in other infections like atypical
mycobacteriosis and leishmaniasis. Cutaneous atypical mycobacterial
infection presents as localized lesions in immunocompetent and is
widespread in immunosuppressed patients. Here, we present a case of
sporotrichoid-lymphocutaneous infection due to atypical mycobacteria, in
a fish-seller under immunosuppressants.
On Dynamics of Double-Diffusive Magnetoconvection in a Non-Newtonian Fluid Layer
Authors: Pan Zhigang , Fan Yanlong , Liang Li , Wang Quan
Published: July 2022

This article concerns the dynamic transitions of a non-Newtonian
horizontal fluid layer with thermal and solute diffusion and in the
presence of vertical magnetic field. First, a linear stability analysis
is done by deriving the principle of exchange of stability condition,
which shows the system loses stability when thermal Rayleigh number
exceeds a critical threshold. Second, we considered the transition
induced by real eigenvalues and complex eigenvalues, respectively, and
two nonlinear transition theorems along with several transition numbers
determining the transition types are obtained via the method of center
manifold reduction. Finally, rigorous numerical computations are
performed to offer examples of possible transitions, as well as the
stable convection patterns. Our results show that when the diffusivities
from big to small are thermal, solute concentration and magnetic
diffusion, both continuous and jump transitions can occur for certain
parameters; and if the diffusivities from big to small is the inverse of
the previous case, only continuous transition induced by real
eigenvalues are observed, which indicate a stationary convection.
Azathioprine induced acute sialadenitis
Authors: Cackamvalli Priyanka Moovara , Khanjar Izzat , Bakri Faten Al
Published: July 2022

Acute sialadenitis is one of the rare adverse effects of Azathioprine.
We report a case of acute submandibular sialadenitis following
initiation of Azathioprine which resolved upon discontinuation of the
drug.
The Educational intervention model for lentil consumption: A strategy that contributes to sustainable development
Authors: Torres-Tenorio Yoliztli Cecilia , Hernandez-Aguilar Claudia , Martinez-Ortíz Efraín Jose
Published: July 2022

It is necessary to propose educational interventions in the population due to economic, social, and environmental situation. Thus, in this research, a transdisciplinary model of educational intervention to increase lentil consumption was proposed. Population was known based on their lifestyle characteristics, health, and pro-health habits, including lentil consumption. The types of lentils marketed in Mexico zone were investigated and characterized in terms of their quality attributes: sanitary, physical and saponins, choosing the best option. food dishes were formulated to teach their preparation and sensory evaluate preferences. As part of the intervention strategy, food dishes were formulated. Training was provided in their preparation and awareness was raised about the importance of lentil consumption for sustainable development. The changes of the participants were evaluated, and they indicated that their changes were mainly attributed to economic aspects, health reasons and care for the environment.  The lentil dishes were accepted by the focus group.
Digital Multimedia Tampering Detection for Forensics Analysis
Authors:   Digital Forensics and Cyber Security Graduate Programme Department of Information Systems & Innovations Ghana Institute of Management & Public Administration Greenhill, Accra, Ghana E-mail: mainoobernard12@gmail.com, Mainoo Bernard
Published: July 2022

In the virtual multimedia era, digital forensics is turning into a rising location of studies way to the huge quantity of picture and video documents generated. Ensuring the integrity of such media is of top-notch significance in lots of situations. This mission has end up extra complex, particularly with the development of symmetrical and asymmetrical community systems which make their authenticity tough. Consequently, it's far definitely vital to find out all feasible modes of manipulation through the improvement of latest forensics detector tools. For example, the symmetry and asymmetry inconsistencies associated with visible characteristic residences are capacity while carried out at a couple of scales and locations. We discover right here this subject matter and advocate a comprehensible smooth taxonomy and a deep assessment of the brand-new studies regarding multimedia forgery detection. Then, an in-intensity dialogue and destiny guidelines for similarly research are provided. This painting gives a possibility for researchers to apprehend the cutting-edge lively subject and to assist them broaden and examine their very own picture/video forensics approaches. Keywords: Digital forensics, Multimedia tampering, Image/video processing, Watermarking, pattern recognition, Active/Passive Tampering Detection
Privacy Preserving Internet of Things (IoT) Forensics
Authors:   Digital Forensics and Cyber Security Graduate Programme Department of Information Systems & Innovations Ghana Institute of Management & Public Administration Greenhill, Accra, Ghana E-mail: odamefrederick@yahoo.com, Odame Frederick Asumang
Published: July 2022

The Internet of Things (IoT) envisions a network of pervasive, connected, and intelligent nodes that interact autonomously and provide a variety of services. IoT objects were a perfect target for cyber assaults because of their wide dispersion, openness, and relatively high processing power. Furthermore, because many IoT nodes collect and process personal or private data, they are becoming a goldmine of information for cybercriminals. As a result, security, particularly the ability to detect compromised nodes, as well as the collection and preservation of evidence of an attack or malicious activity, emerge as a top priority in the effective deployment of IoT networks. Key words: Information Security, IoT, Privacy Preserving, Cyber Security, Cyber Criminals
SIFT Multi-Purpose Forensic Operating System For Digital Forensic Process.
Authors:   Digital Forensics and Cyber Security Graduate Programme Department of Information Systems & Innovations Ghana Institute of Management & Public Administration Greenhill, Accra, Ghana E-mail: francis.wodugah@st.gimpa.edu.gh, Wodugah Francis
Published: July 2022

The number of cyber incidents in which computer system or device is currently increasing every day. This requiring the opening up of forensic investigations in to multi-purpose forensic operating system for digital forensic process, a research that can shed light on what has occurred, In order to be able to provide investigators with proper solutions. for performing complete and efficient examinations in this new environment, operating systems platform and devices are being studied from a forensic perspective so that tools and procedures can be designed accordingly Keywords: Forensic Investigations, Cyber Forensic, Multi-Purpose Forensic Operating.
Performance of spark-ignition engine at various fuel octane numbers
Authors: Prihatno Anton , Hendrawan Andi
Published: July 2022

The paper describes the performance of a spark-ignition engine at various fuel octane numbers. This study was realised using a 150cc automatic motorcycle with a compression ratio of 10.6:1. The experiments were conducted on three types of gasoline with different research octane numbers (RON), namely 88, 90, and 92. The torque and power of the engine were evaluated using a dyno test, while fuel consumption was simultaneously monitored during the experiments. The data were then collected and analysed using Motorcycle Communication System (MCS). The MCS measurements indicated that fuel with RON 92 allows the vehicle to reach the top speed and rotation at a gas opening angle of 25° - 79°. Applying fuel with the proper octane number in an engine with a particular compression ratio can maintain optimal engine performance. Decreasing the fuel's octane rating from the recommended conditions based on the engine specifications causes a decrease in engine performance. Torque and power tend to drop, and fuel is not economical.
DIVERSIFICATION PRODUCTION AND CONSUMPTION OF MORINGA OLEIFERA BECOMING MORINGA LEAF EXTRACT CAPSULES AS AN ALTERNATIVE FOR FOOD RESILIENCE
Authors: Budiman Asep , Lucky Radi Raden , Permata Sari Dewi , Taufik Nuryanti
Published: July 2022

Since the occurrence of the COVID-19 pandemic at the end of 2019 until now, the world is threatened with a food crisis, including in Indonesia. The food crisis occurs as a result of the uncertainty of when the pandemic will end. This situation made the Indonesian government start to include food security as a priority program of the government. One of the food security programs declared by the Ministry of Agriculture is the food production and consumption program. Diversification of food production and consumption is the diversification of the types of food consumed and produced with the aim of improving the quality of human resources, developing agriculture in the food sector and improving community nutrition. In this regard, Anaka Village, Kawalu Sub-district is one of the areas in Tasikmalaya that has Moringa farming products, but the community around the plant only uses these agricultural products to make home-cooked food. Therefore, the purpose of this community service program is to provide knowledge and training regarding the production and consumption of Moringa Oleiferainto Moringa leaf extract capsules with the hope that the community will be able to take advantage of the maximum Moringa crop yields and can have business opportunities to generate new sources of income to survive. living in the midst of a food crisis.
The Use of Duolingo in Enhancing Students' Vocabulary Mastery at SMA Negeri 3 Bangko Pusako During Pandemic Covid-19
Authors: Erfiani Erfiani , Miski Cut Raudhatul
Published: July 2022

Abstract Based on the writer’s observation in teaching and learning process, the students’ frequently encounter obstacles to memorize the words, confuse the meaning of the words, and difficulty in pronunciation. To solve this problem, the writer used a media to improve the students’ mastery in vocabulary. The media was using Duolingo. The aim of this research was to find out any significant difference of students’ vocabulary mastery between students’ taught by using Duolingo and without using Duolingo at SMA Negeri 3 Bangko Pusako During Pandemic Covid-19. This research was a quantitative research by an quasi-experimental design. In this research, there were two classes as a sample, that classes were an experimental class and control class. The population of this research were tenth grade of SMA Negeri 3 Bangko Pusako was 156 students’ which were 30 students as sample of this study using purposive sampling technique. The result of the research showed that the students’ on vocabulary mastery in experimental class was very good category and in control class was good category. On the independents sample T-test, the significant value was 0.000 lower than alpha 0.05, which meant the alternative hypothesis (Ha) was accepted while null hypothesis (HO) was rejected. It means that, there was any significant difference of students’ vocabulary mastery between students’ taught by using Duolingo and without using Duolingo at SMA Negeri 3 Bangko Pusako.  Keywords: Vocabulary Mastery, Duolingo, Covid-19
Indonesian Government Diplomacy on Protecting Indonesian Migrant Workers in Papua New Guinea During COVID-19 Pandemic
Authors: Suryanti Made Selly Dwi , Sinaga Melpayanty
Published: July 2022

COVID-19 Pandemic that started from the end of 2019 and developed in 2020 has changed international world order. That changed felt by all countries in the world, including Indonesia. The rapid raising of casualties made the government taking a lockdown policy. It was meant to protect their citizens and prevent a more massive spreading. That protection is not only applied for the citizens in the country but also for the citizens living abroad like Indonesian migrant workers. One particular case that became the focus of this research is the migrant workers who works in Papua New Guinea (PNG). Human right is a main instrument in protecting the citizens. That is the importance of government in this case. This research aims to analyze Indonesian diplomacy strategies in protecting the rights of migrant workers who works in PNG during the Pandemic with humanity aspect as its main concern. Method that is used in this research is a descriptive qualitative using primary and secondary data through interviews and literature study from relevant and validated sources. The result of this research shows that Indonesian Government is taking the model of protection diplomacy in protecting Indonesian migrant workers in PNG.
MACROFUNGI INVENTARITATION AT THE PINE FOREST OF KRAGILAN, MAGELANG
Authors: Noviyanti Nita , Mahardhika Wahyu Aji , Tri Lunggani Arina , Permana Putra Ivan
Published: July 2022

The pine forest of Kragilan village, Magelang, is a forested area on the west slopes of Mount Merbabu with a humid environmental condition. The conditions make this region suitable for the growth of a macrofungal community. The macrofungal inventory in Merbabu Mountain is very limited and this is inversely proportional to the increasing deforestation. Thus, the macrofungal inventory is a fundamental way of managing natural conservation in this area. The study aimed to provide information and the potency of macrofungi found in the pine forest area of Kragilan, Magelang. The method used is purposive sampling in the research area, and the fungi obtained were identified based on characteristics with some related references. This research described eight species of eight different genera, including one from the Ascomycota (Xylaria sp.), and seven others from the Basidiomycota (Auricularia auriculajudae, Lentinellus sp., Mycena sp., Skeletocutis sp., Gymnopilus sp., Coprinopsis sp., and Coprinellus disseminatus). The current study is the first report on macrofungi diversity in the research area. Further exploration is still needed to record the macrofungal diversity on the western slopes of the Kragilan pine forest.
Community-Based Art Projects in San Francisco Chinatown: A Survival Strategy
Authors: Bao Xiaoxiao , Leung Hoi
Published: July 2022

While research about contemporary Asian arts exhibited in mega museums has attracted growing attention, there is little dialogue concerning community-based art practices in everyday Asian and Asian American neighborhoods. This interview article highlights community-based art projects led by a grassroots organization, the Chinese Culture Center of San Francisco (CCC), to help understand Chinatown’s stories as shared and lived by the community during a challenging time. Hoi Leung, CCC’s chief curator, explained how the organization mobilized art to share diverse local stories, celebrate a sense of belonging, and raise public awareness about racial justice issues within the communities it serves. To counter socially constructed assumptions about Chinatown and its residents, CCC actively develops cross-sector partnerships to centralize underrepresented voices through community-based arts and projects.
Disrupting White Vision: Pedagogical Strategies Against White Supremacy
Authors: Schultz Heath
Published: July 2022

This paper contributes to a pedagogy of antiracist art education by offering strategies to disrupt white supremacy and the “white savior complex” in the classroom. I begin by discussing students’ commonly held internalizations of white supremacy. I next outline my experience teaching Marlon Riggs’ documentary Ethnic Notions (1986) to introduce a history of racist image production including minstrelsy and racist archetypes like Uncle Tom, Sambo, Mammy, Coon, and the Savage in antebellum, postbellum, and colonial contexts. Next, I use a close reading of two recent examples to illustrate how these anti-black tropes continue to inform contemporary visual culture. The first example is a philanthropic commercial for the “Christian Children’s Fund” that utilizes the most problematic aspects of the white savior in colonialist aesthetics. In the second example, I analyze a comedic skit from Saturday Night Live (SNL) that acts as a critical response to the commercial. A satirical take on the white savior trope, the skit is both an alternative to and subversion of the history of racist and imperialist imagery. With a historically informed knowledge of how imagery is used to uphold white supremacy, we can make direct connections between histories of racialized imagery and the art world and build lessons for an antiracist pedagogy.
Art Education as Exhibition: Reconceptualizing Cultural History in Singapore through an Art Response to Ah Ku and Karayuki-san Prostitution
Authors: Chung Oi Kay Kok
Published: July 2022

In this essay, the author discusses her understanding of art education in relation to her exhibited artworks, which were developed on the basis of research on particular historical figures in Singapore. These historical figures were referred to in the book entitled Ah Ku and Karayuki-san:-Prostitution in Singapore, 1870-1940, written by James Francis Warren who is a renowned ethnohistorian and professor at Murdoch University in Australia. According to Warren (2003), both terms referred to prostitutes. Ah Ku was a term that was used to address in Cantonese2 a woman or lady irrespective of age, the polite way to address a Chinese prostitute in colonial Singapore3. Karayuki-san was the word used traditionally by the Japanese of Amakusa Island and the Shimabara Peninsula, Northwest Kyushu, to describe rural women who emigrated to Southeast Asia and the Pacific in search of a livelihood. The author translated the contents of Warren’s book into a series of paintings that were used as an art education tool to educate viewers about the history of Ah Ku and Karayuki-san. In this essay, the author addresses her understanding of art education, re-defines the history of Chinese and Japanese immigrant prostitutes as part of Singapore cultural heritage, and describes the research methods used to derive the artworks as well as the exhibition format to explain the relationship between the meanings of the paintings and Warren’s book.
Problems Related to the Practice of Video Education in Japan
Authors: HASE Kaihei
Published: July 2022

The practice of video production as a means of learning through art is closely related to the concept of media literacy, although misuse of the term in Japan has created some obstacles. First, an imbalance exists between video literacy’s two educational aspects: using video to express ideas and interpreting the expressions used within them. Second, unqualified instructors are frequently tasked to teach video production in an educational context. Third, rapid changes in social environments lead to disparities between social reality and educational objectives. These problems are rooted in an outdated understanding of media literacy as a concept in Japan, which in turn can be attributed to an inadequate translation of the term into Japanese that strips away its creative connotations.