bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Fig. 6 from Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination Therapy
Authors: Phillips Gail D. Lewis , Fields Carter T. , Li Guangmin , Dowbenko Donald , Schaefer Gabriele , Miller Kathy , Andre Fabrice , Burris Howard A. , Albain Kathy S. , Harbeck Nadia , Dieras Veronique , Crivellari Diana , Fang Liang , Guardino Ellie , Olsen Steven R. , Crocker Lisa M. , Sliwkowski Mark X.
Published: April 2023

PDF file 67K, TDM4373g Phase Ib Clinical Study Design
Supplementary Figure Legend from Direct Inhibition of Retinoblastoma Phosphorylation by Nimbolide Causes Cell-Cycle Arrest and Suppresses Glioblastoma Growth
Authors: Karkare Swagata , Chhipa Rishi Raj , Anderson Jane , Liu Xiaona , Henry Heather , Gasilina Anjelika , Nassar Nicholas , Roychoudhury Jayeeta , Clark Jason P , Kumar Ashish , Pauletti Giovanni M. , Ghosh Pradip K. , Dasgupta Biplab
Published: April 2023

PDF file - 71K
Supplementary Figure S6 from GKN1–miR-185–DNMT1 Axis Suppresses Gastric Carcinogenesis through Regulation of Epigenetic Alteration and Cell Cycle
Authors: Yoon Jung Hwan , Choi Yoo Jin , Choi Won Suk , Ashktorab Hassan , Smoot Duane T. , Nam Suk Woo , Lee Jung Young , Park Won Sang
Published: April 2023

Supplementary Figure S6 - PDF file 1180K, Effects of miR-185 in MKN1 and MKN28 cells
Supplementary Table 2 from PIK3CA Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell Carcinoma
Authors: Shigaki Hironobu , Baba Yoshifumi , Watanabe Masayuki , Murata Asuka , Ishimoto Takatsugu , Iwatsuki Masaaki , Iwagami Shiro , Nosho Katsuhiko , Baba Hideo
Published: April 2023

PDF File - 28K, Number at risk in survival analyses.
Supplementary Figure 5 from Reducing TNF Receptor 2+ Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients
Authors: Govindaraj Chindu , Tan Peter , Walker Patricia , Wei Andrew , Spencer Andrew , Plebanski Magdalena
Published: April 2023

PDF file - 1448K, The proportion of TNFR2- and TNFR2+ effector T cells between healthy and AML patients.
Supplementary Figure 3 from Reducing TNF Receptor 2+ Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients
Authors: Govindaraj Chindu , Tan Peter , Walker Patricia , Wei Andrew , Spencer Andrew , Plebanski Magdalena
Published: April 2023

PDF file - 1153K, TNFR2 levels are positively correlated with CXCR4 expression on Tregs.
Supplementary Table 2 from High Phospho-Stathmin(Serine38) Expression Identifies Aggressive Endometrial Cancer and Suggests an Association with PI3K Inhibition
Authors: Wik Elisabeth , Birkeland Even , Trovik Jone , Werner Henrica M.J. , Hoivik Erling A. , Mjos Siv , Krakstad Camilla , Kusonmano Kanthida , Mauland Karen , Stefansson Ingunn M. , Holst Frederik , Petersen Kjell , Oyan Anne M. , Simon Ronald , Kalland Karl H. , Ricketts William , Akslen Lars A. , Salvesen Helga B.
Published: April 2023

PDF file - 50K, Validations series. Cox's proportional hazard regression model used to estimate the prognostic value of pStathmin(S38) in endometrial carcinomas, in relation to histopathologic variables and Stathmin.
Supplementary Table 1 from High Phospho-Stathmin(Serine38) Expression Identifies Aggressive Endometrial Cancer and Suggests an Association with PI3K Inhibition
Authors: Wik Elisabeth , Birkeland Even , Trovik Jone , Werner Henrica M.J. , Hoivik Erling A. , Mjos Siv , Krakstad Camilla , Kusonmano Kanthida , Mauland Karen , Stefansson Ingunn M. , Holst Frederik , Petersen Kjell , Oyan Anne M. , Simon Ronald , Kalland Karl H. , Ricketts William , Akslen Lars A. , Salvesen Helga B.
Published: April 2023

PDF file - 50K, Primary investigation series. Cox's proportional hazard regression model used to estimate the prognostic value of pStathmin(S38) in endometrial carcinomas, in relation to histopathologic variables and Stathmin.
Supplementary Methods from Trial Designs for Personalizing Cancer Care: A Systematic Review and Classification
Authors: Tajik Parvin , Zwinderman Aleiko H. , Mol Ben W. , Bossuyt Patrick M.
Published: April 2023

PDF file - 60K
Supplementary Table S5 from Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
Authors: Iwaya Takeshi , Fukagawa Takeo , Suzuki Yutaka , Takahashi Yusuke , Sawada Genta , Ishibashi Masahisa , Kurashige Junji , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Endo Fumitaka , Katagiri Hirokatsu , Ishida Kaoru , Kume Kohei , Nishizuka Satoshi , Iinuma Hisae , Wakabayashi Go , Mori Masaki , Sasako Mitsuru , Mimori Koshi
Published: April 2023

XLS file 15K, Supplementary Table S5. Comparison of Histone mRNA metabolism-associated genes expression in BM samples from GC patients
Supplementary Figure Legend from Genetic Profiling to Determine Risk of Relapse-Free Survival in High-Risk Localized Prostate Cancer
Authors: Barnett Christine M. , Heinrich Michael C. , Lim Jeong , Nelson Dylan , Beadling Carol , Warrick Andrea , Neff Tanaya , Higano Celestia S. , Garzotto Mark , Qian David , Corless Christopher L. , Thomas George V. , Beer Tomasz M.
Published: April 2023

PDF file 56K, Supplementary figure legend
Supplementary Table S3 from Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
Authors: Iwaya Takeshi , Fukagawa Takeo , Suzuki Yutaka , Takahashi Yusuke , Sawada Genta , Ishibashi Masahisa , Kurashige Junji , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Endo Fumitaka , Katagiri Hirokatsu , Ishida Kaoru , Kume Kohei , Nishizuka Satoshi , Iinuma Hisae , Wakabayashi Go , Mori Masaki , Sasako Mitsuru , Mimori Koshi
Published: April 2023

XLS file 10K, Gene set enrichment analysis of derived from RNA-seq Analysis of BM samples from GC patients
Supplementary Data from Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
Authors: Iwaya Takeshi , Fukagawa Takeo , Suzuki Yutaka , Takahashi Yusuke , Sawada Genta , Ishibashi Masahisa , Kurashige Junji , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Endo Fumitaka , Katagiri Hirokatsu , Ishida Kaoru , Kume Kohei , Nishizuka Satoshi , Iinuma Hisae , Wakabayashi Go , Mori Masaki , Sasako Mitsuru , Mimori Koshi
Published: April 2023

PDF file 146K, Supplementary Data
Supplementary Table S5 from Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer
Authors: Dai Wei , Zeller Constanze , Masrour Nahal , Siddiqui Nadeem , Paul James , Brown Robert
Published: April 2023

Supplementary Table S5 - PDF file 104K, PFS analysis in SGCTG cohort
Supplementary Table 1 from HIF-1α of Bone Marrow Endothelial Cells Implies Relapse and Drug Resistance in Patients with Multiple Myeloma and May Act as a Therapeutic Target
Authors: Ria Roberto , Catacchio Ivana , Berardi Simona , De Luisi Annunziata , Caivano Antonella , Piccoli Claudia , Ruggieri Vitalba , Frassanito Maria Antonia , Ribatti Domenico , Nico Beatrice , Annese Tiziana , Ruggieri Simona , Guarini Attilio , Minoia Carla , Ditonno Paolo , Angelucci Emanuele , Derudas Daniele , Moschetta Michele , Dammacco Franco , Vacca Angelo
Published: April 2023

PDF file - 17K, Real Time RT-PCR Primers.
Supplementary Table S1 from Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer
Authors: Dai Wei , Zeller Constanze , Masrour Nahal , Siddiqui Nadeem , Paul James , Brown Robert
Published: April 2023

Supplementary Table S1 - PDF file 65K, Patient characteristics
Supplementary Table 2 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Authors: Rao Guanhua , Wang Hongyi , Li Baowei , Huang Li , Xue Danfeng , Wang Xiaohui , Jin Haijing , Wang Jun , Zhu Yushan , Lu Youyong , Du Lei , Chen Quan
Published: April 2023

XLSX file - 121K, Characteristics of Patients
Supplementary Table 1 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Authors: Rao Guanhua , Wang Hongyi , Li Baowei , Huang Li , Xue Danfeng , Wang Xiaohui , Jin Haijing , Wang Jun , Zhu Yushan , Lu Youyong , Du Lei , Chen Quan
Published: April 2023

XLSX file - 190K, Real-time primer sequence
Supplementary Materials and Methods from Busulfan in Infant to Adult Hematopoietic Cell Transplant Recipients: A Population Pharmacokinetic Model for Initial and Bayesian Dose Personalization
Authors: McCune Jeannine S. , Bemer Meagan J. , Barrett Jeffrey S. , Scott Baker K. , Gamis Alan S. , Holford Nicholas H.G.
Published: April 2023

PDF file 34K, Additional description of data incorporation and quality assurance procedures
Supplementary Figure 2 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence
Authors: Allen Michael D. , Thomas Gareth J. , Clark Sarah , Dawoud Marwa M. , Vallath Sabarinath , Payne Sarah J. , Gomm Jennifer J. , Dreger Sally A. , Dickinson Sarah , Edwards Dylan R. , Pennington Caroline J. , Sestak Ivana , Cuzick Jack , Marshall John F. , Hart Ian R. , Jones J. Louise
Published: April 2023

PDF file - 108K, Supplementary Figure 2. alphavbeta6 functional assays in the beta6-1089 cell line using RNAi.
Supplementary Figure 6 from Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions
Authors: Dai Jinlu , Zhang Honglai , Karatsinides Andreas , Keller Jill M. , Kozloff Kenneth M. , Aftab Dana T. , Schimmoller Frauke , Keller Evan T.
Published: April 2023

PDF file 173K, Impact of cabozantinib on MET, phospho-MET, VEGFR2 and phospho-VEGFR2 expression of subcutaneous LuCaP 35 and intratibial C4-2B tumors in mice
Supplementary Figure Legend from Antitumoral Activity of Lenalidomide in In Vitro and In Vivo Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27KIP1 Complexes
Authors: Moros Alexandra , Bustany Sophie , Cahu Julie , Saborit-Villarroya Ifigènia , Martínez Antonio , Colomer Dolors , Sola Brigitte , Roué Gaël
Published: April 2023

PDF file - 64K
Supplementary Figure 1 from GA201 (RG7160): A Novel, Humanized, Glycoengineered Anti-EGFR Antibody with Enhanced ADCC and Superior In Vivo Efficacy Compared with Cetuximab
Authors: Gerdes Christian A. , Nicolini Valeria Gonzalez , Herter Sylvia , van Puijenbroek Erwin , Lang Sabine , Roemmele Michaela , Moessner Ekkehard , Freytag Olivier , Friess Thomas , Ries Carola H. , Bossenmaier Birgit , Mueller Hans Joachim , Umaña Pablo
Published: April 2023

PDF file - 307K, ADCC activity of GA201 using PMBCs as effector cells at E:T ratios of 1:1, 5:1 (24 hour LDH release measured) and 10:1 (4 hour LDH release measured). Multiple ADCC experiments were performed using a variety of different effector:target cell ratios (E:T). Figure 3 in the manuscript displays the results of ADDC assays using NK-92 cells as effectors at an E:T ratio of 3:1 and using human peripheral blood mononuclear cells (PBMCs) as effectors at an E:T ratio of 25:1. These E:T ratios represent the optimal experimental conditions that generated robust ADCC signal read outs. Supplementary Fig. S1 shows additional ADCC results for the MKN45 cell line using human PBMCs as effector cells at an E:T ratios of 1:1, 5:1 and 10:1. The data shows that under all the tested conditions GA201 exhibited superior cell killing compared with cetuximab. The overall ADCC activity with both antibodies using PMBCs at an E:T ratio of 1:1 was substantially lower than at 5:1 or 10:1.
Supplementary Figure 1 from Antitumoral Activity of Lenalidomide in In Vitro and In Vivo Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27KIP1 Complexes
Authors: Moros Alexandra , Bustany Sophie , Cahu Julie , Saborit-Villarroya Ifigènia , Martínez Antonio , Colomer Dolors , Sola Brigitte , Roué Gaël
Published: April 2023

PDF file - 1473K, Recounting of cells with nuclear positivity for cyclin D1 and p27KIP1 in (A) tumor specimen from two MCL patients presenting with a classical (Pt#1) or a blastoid (Pt#3)subtype and (B) in 6 MCL cell lines from either high (Rec-1, JBR and ZBR) or low (JVM-2, Jeko-1 and ZBR) expression profile.
Supplementary Table 4 from Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity
Authors: McWhinney-Glass Sarah , Winham Stacey J. , Hertz Daniel L. , Yen Revollo Jane , Paul Jim , He Yijing , Brown Robert , Motsinger-Reif Alison A. , McLeod Howard L.
Published: April 2023

PDF file, 190K, Results of the 69 significant SNPs in the discovery cohort, for both the discovery and replication set. Covariates ECOG performance status, treatment status, time to first toxicity, and grade of GI toxicity.
Supplementary Table 4 from DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes
Authors: Hascher Antje , Haase Ann-Kristin , Hebestreit Katja , Rohde Christian , Klein Hans-Ulrich , Rius Maria , Jungen Dominik , Witten Anika , Stoll Monika , Schulze Isabell , Ogawa Seishi , Wiewrodt Rainer , Tickenbrock Lara , Berdel Wolfgang E. , Dugas Martin , Thoennissen Nils H. , Müller-Tidow Carsten
Published: April 2023

XLSX file - 655K, Supplementary Table S4 - annotated DNA methylation in confirmed promoter DMRs (RRBS) in HTB56.
Supplementary Tables 1 - 2 from Prognostic and Predictive Value of Tumor Vascular Endothelial Growth Factor Gene Amplification in Metastatic Breast Cancer Treated with Paclitaxel with and without Bevacizumab; Results from ECOG 2100 Trial
Authors: Schneider Bryan P. , Gray Robert J. , Radovich Milan , Shen Fei , Vance Gail , Li Lang , Jiang Guanglong , Miller Kathy D. , Gralow Julie R. , Dickler Maura N. , Cobleigh Melody A. , Perez Edith A. , Shenkier Tamara N. , Vang Nielsen Kirsten , Müller Sven , Thor Ann , Sledge George W. , Sparano Joseph A. , Davidson Nancy E. , Badve Sunil S.
Published: April 2023

PDF file - 121K, Table 1. Supplemental Table 1. Comparison of the Patients Analyzable for VEGFA Amplification to All Patients Enrolled on E2100 Table 2. Estimated Progression Free Survival treatment hazard ratios (arm A vs. arm B) and 95% confidence intervals for various subsets. Comparison between the cases analyzable for VEGFA amplification and all cases in E2100
Supplementary Figure Legends from Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells
Authors: Rapoport Aaron P. , Aqui Nicole A. , Stadtmauer Edward A. , Vogl Dan T. , Xu Yin Yan , Kalos Michael , Cai Ling , Fang Hong-Bin , Weiss Brendan M. , Badros Ashraf , Yanovich Saul , Akpek Gorgun , Tsao Patricia , Cross Alan , Mann Dean , Philip Sunita , Kerr Naseem , Brennan Andrea , Zheng Zhaohui , Ruehle Kathleen , Milliron Todd , Strome Scott E. , Salazar Andres M. , Levine Bruce L. , June Carl H.
Published: April 2023

PDF file - 48KB
Supplementary Figure 1 from Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers
Authors: Prosniak Michael , Harshyne Larry A. , Andrews David W. , Kenyon Lawrence C. , Bedelbaeva Kamila , Apanasovich Tatiyana V. , Heber-Katz Ellen , Curtis Mark T. , Cotzia Paolo , Hooper D. Craig
Published: April 2023

PDF - 102K, Assessment of the expression of mRNAs specific for the Treg marker FoxP3 and CMV IL-10 in glioma tissues and epilepsy specimens.
Supplementary Figure S4 from Expression Defect Size among Unclassified MLH1 Variants Determines Pathogenicity in Lynch Syndrome Diagnosis
Authors: Hinrichsen Inga , Brieger Angela , Trojan Jörg , Zeuzem Stefan , Nilbert Mef , Plotz Guido
Published: April 2023

PDF file - 56 KB, Microsatellite stability in cultured HEK293 cells. HEK293 and HEK293T cells, each derived from a previously singularized clone, were singularized in 96-well plates. DNA was extracted from colonies after 14 days by resuspension in extraction buffer (Tris 10 mM, EDTA 1 mM, proteinase K 50m �g/ml). DNA binding proteins were removed by an incubation of 2h at 60 {degree sign}C, subsequently proteinase K was heat inactivated at 95{degree sign}C for 15 min. Extracted DNA was stored at -20 {degree sign}C. Microsatellite status of BAT25 and BAT26 was determined using dye-labeled primers. Successful amplification was controlled by agarose gel electrophoresis. The samples were cleaned with High Pure PCR Product Purification Kit (Roche Applied Sciences) and injected with size standard (Gene Scan 500 ROX Size Standard, Applied Biosystems) into an 3130xl Genetic Analyzer, Applied Biosystems. Peak Scanner Software (Applied Biosystems) was used for analysis. Colonies with identical sizes were counted, and the shift of the microsatellite size in comparison to the original size of the source clones is given.
Supplementary Table 3 from Molecular Classification of Malignant Pleural Mesothelioma: Identification of a Poor Prognosis Subgroup Linked to the Epithelial-to-Mesenchymal Transition
Authors: de Reyniès Aurélien , Jaurand Marie-Claude , Renier Annie , Couchy Gabrielle , Hysi Ilir , Elarouci Nabila , Galateau-Sallé Françoise , Copin Marie-Christine , Hofman Paul , Cazes Aurélie , Andujar Pascal , Imbeaud Sandrine , Petel Fabien , Pairon Jean-Claude , Le Pimpec-Barthes Francoise , Zucman-Rossi Jessica , Jean Didier
Published: April 2023

PDF file - 58KB, Primer sequences used for BAP1 and CDKN2B gene analysis.
Supplementary Figure 1 from MGMT-STP27 Methylation Status as Predictive Marker for Response to PCV in Anaplastic Oligodendrogliomas and Oligoastrocytomas. A Report from EORTC Study 26951
Authors: van den Bent Martin J. , Erdem-Eraslan Lale , Idbaih Ahmed , de Rooi Johan , Eilers Paul H.C. , Spliet Wim G.M. , den Dunnen Wilfred F.A. , Tijssen Cees , Wesseling Pieter , Sillevis Smitt Peter A.E. , Kros Johan M. , Gorlia Thierry , French Pim J.
Published: April 2023

Supplementary figure 1 - PDF file 810K, Comparison of baseline variables on Humanmethylation450 beadchips
Supplementary Figure 3 from Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma
Authors: Shi Jie-Yi , Gao Qiang , Wang Zhi-Chao , Zhou Jian , Wang Xiao-Ying , Min Zhi-Hui , Shi Ying-Hong , Shi Guo-Ming , Ding Zhen-Bin , Ke Ai-Wu , Dai Zhi , Qiu Shuang-Jian , Song Kang , Fan Jia
Published: April 2023

PDF file - 481K, Kaplan-Meier analysis of OS and RFS for (A) MIL-Bs and (B)penetration of MIL-Bs through tumor capsule in the validation cohort.
Supplementary Table 3 from A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets
Authors: Adamia Sophia , Haibe-Kains Benjamin , Pilarski Patrick M. , Bar-Natan Michal , Pevzner Samuel , Avet-Loiseau Herve , Lode Laurence , Verselis Sigitas , Fox Edward A. , Burke John , Galinsky Ilene , Dagogo-Jack Ibiayi , Wadleigh Martha , Steensma David P. , Motyckova Gabriela , Deangelo Daniel J. , Quackenbush John , Stone Richard , Griffin James D.
Published: April 2023

PDF file - 66K, Table S3 shows CD13 and its splice variant expression patterns in 193 AML patients.
Supplementary Figure Legend from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file - 109K
Supplementary Figure 6 from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file - 1486K, Supplementary Figure S6. Rap1B induces p38-mediated phosphorylation of TTP, which promotes secretion of pro-inflammatory mediators. (A) Whole cell lysates from UM-SCC-81B cells treated with IL-1β for 0, 2, 5, or 10 minutes were immunoblotted with phospho-p38(pp38), p38, rap1B and actin (loading control) antibodies. Active rap1B (rap1BGTP) was retrieved by a ralGDS pull-down assay. p38 was used for normalization of pp38 and rap1B was used for normalization of rap1BGTP. Signal intensity was quantified, normalized to its corresponding loading control and expressed as percent of time zero. Data are representative of three independent experiments. (B) UM-SCC-81B cells were transfected with two siRNAs targeting rap1B (si6 and si7) or NT and were stimulated with IL-1β or PBS (control) for 10 minutes. Whole cell lysates were immunoblotted with pp38, p38 and rap1B antibodies. Signal intensity was quantified, normalized to p38 and expressed as percent of stimulated NT. (C) UM-SCC-81B cells were transfected with sip38 or NT treated with PBS (control) or IL-1β for 10 minutes. Whole cell lysates were immunoprecipitated with TTP antibody bound AminoLink Plus Coupling Resin beads and eluted samples were immunoblotted with phosphoserine and TTP antibody. Signal intensity was quantified, normalized to input and expressed as percent of unstimulated NT. Whole cell lysates from NT and sip38 were also immunoblotted with pp38, p38 and actin antibodies. Signal intensity was quantified, normalized to p38 then actin and expressed as percent of unstimulated NT. Three independent experiments were performed. (D) UM-SCC-81B cells were transfected with sip38 or NT and whole cell lysates were immunoblotted for p38 and actin. Signal intensity was quantified, normalized to Actin and expressed as percent of NT. Interleukin-6 (IL-6) secretion was determined in conditioned media via ELISA with two replicates in each of three independent experiments. (*p<0.01).
Supplementary Figure 4 from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file - 1747K, Supplementary Figure S4 Downregulation of TTP promotes invasion via upregulation of IL-6, MMP9 and MMP2. (A) UM-SCC-81B cells were transiently transfected with NT or siTTP. Gelatin zymography was used to quantify MMP9 and MMP2 in conditioned medium and was expressed as percent of corresponding control. Data are representative of two independent experiments. TTP knockdown was verified. (B) Whole-cell lysates were prepared from UM-SCC-81B-shControl or shTTP cells transiently transfected with siIL-6, siMMP9, siMMP2 or NT and were immunobloted with IL-6, MMP9, or MMP2 and actin antibodies. Signal intensity was quantified, normalized to actin, and expressed as percent of control. (C) Invasion of UM-SCC-81B-shTTP cells transiently transfected with siIL-6, siMMP9, siMMP2 and NT was quantified and expressed as percent of NT. Data are representative of two independent experiments with three replicates in each experiment. (*p<0.01)
Supplementary Figure 1 from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file - 9009K, Supplementary Figure S1 Representative staining for IL-6 showing examples of no, low, medium and high staining intensity.Tissue sections of SCCHN TMA were incubated with the affinity-purified IL6 polyclonal antibody and DAB detection. Slides were counterstained with hematoxylin. (Bars = 60 M)
Supplement File from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Supplement file: Materials and Methods
Figure S5 from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

mRNA expression of ANO1 in ESCC cell lines. X. Name of ESCC cell lines. Y. The relative mRNA expression of ANO1 compared with GAPDH.
Supplementary Tables 1 - 4 from MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer
Authors: Yu San-Jian , Hu Jing-Ying , Kuang Xia-Ying , Luo Jian-Min , Hou Yi-Feng , Di Gen-Hong , Wu Jiong , Shen Zhen-Zhou , Song Hou-Yan , Shao Zhi-Ming
Published: April 2023

PDF file - 78K, Table S1. List of primer and siRNA sequences; Table S2. Intersection between Predict target of miR-200a and genes that regulate the apoptotic processes; Table S3. The number of zebrafish embryos with migrating tumor (Dil) cells transfected with miR-200a, YAP1 siRNA, miR-Ctrl , Scramble RNA, antagomiR-200a and antagomiR-Ctrl respectively; Table S4. The number of migrated cells per tail vein of zebrafish embryos that had migrating tumor (Dil) cells transfected with miR-200a, YAP1 siRNA, miR-Ctrl and Scramble RNA, antagomiR-200a and antagomiR-Ctrl respectively
Supplementary Figure 3 from MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer
Authors: Yu San-Jian , Hu Jing-Ying , Kuang Xia-Ying , Luo Jian-Min , Hou Yi-Feng , Di Gen-Hong , Wu Jiong , Shen Zhen-Zhou , Song Hou-Yan , Shao Zhi-Ming
Published: April 2023

PDF file - 208K, Colony formation assay for miR-200a candidate targets
Supplemental Data 3 from Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma
Authors: Grupp Stephan A. , Prak Eline Luning , Boyer Jean , McDonald Kenyetta R. , Shusterman Suzanne , Thompson Edward , Callahan Colleen , Jawad Abbas F. , Levine Bruce L. , June Carl H. , Sullivan Kathleen E.
Published: April 2023

B cell maturation was defined by flow cytometry
Supplemental Data 2 from Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma
Authors: Grupp Stephan A. , Prak Eline Luning , Boyer Jean , McDonald Kenyetta R. , Shusterman Suzanne , Thompson Edward , Callahan Colleen , Jawad Abbas F. , Levine Bruce L. , June Carl H. , Sullivan Kathleen E.
Published: April 2023

Representative flow cytometry plots
Supplementary Figures 1 - 3, Table 1 from High-Resolution Array CGH and Gene Expression Profiling of Alveolar Soft Part Sarcoma
Authors: Selvarajah Shamini , Pyne Saumyadipta , Chen Eleanor , Sompallae Ramakrishna , Ligon Azra H. , Nielsen Gunnlaugur P. , Dranoff Glenn , Stack Edward , Loda Massimo , Flavin Richard
Published: April 2023

PDF file - 626K, One supplementary table detailing the relationship between aCGH abnormalities and the clinicopathological characteristics of the study cohort. Three supplementary figures illustrating i) the design of the FISH probes ii) key biological processes, gene signatures and pathways enriched among the top differentially expressed genes and iii)Ingenuity Pathway Analysis for potential Pax6 targets.
Supplementary Methods from Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model
Authors: Morales-Kastresana Aizea , Sanmamed Miguel F. , Rodriguez Inmaculada , Palazon Asis , Martinez-Forero Ivan , Labiano Sara , Hervas-Stubbs Sandra , Sangro Bruno , Ochoa Carmen , Rouzaut Ana , Azpilikueta Arantza , Bolaños Elixabet , Jure-Kunkel Maria , Gütgemann Ines , Melero Ignacio
Published: April 2023

PDF file - 129K
Supplementary Figure 7 from Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex
Authors: Guvenc Hacer , Pavlyukov Marat S. , Joshi Kaushal , Kurt Habibe , Banasavadi-Siddegowda Yeshavanth K. , Mao Ping , Hong Christopher , Yamada Ryosuke , Kwon Chang-Hyuk , Bhasin Deepak , Chettiar Somsundaram , Kitange Gaspar , Park In-Hee , Sarkaria Jann N. , Li Chenglong , Shakhparonov Mihail I. , Nakano Ichiro
Published: April 2023

PDF file - 7861K, LLP-3 inhibits proliferation and induces apoptosis ex vivo (related to Figure 5)
Supplementary Figure 5 from Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex
Authors: Guvenc Hacer , Pavlyukov Marat S. , Joshi Kaushal , Kurt Habibe , Banasavadi-Siddegowda Yeshavanth K. , Mao Ping , Hong Christopher , Yamada Ryosuke , Kwon Chang-Hyuk , Bhasin Deepak , Chettiar Somsundaram , Kitange Gaspar , Park In-Hee , Sarkaria Jann N. , Li Chenglong , Shakhparonov Mihail I. , Nakano Ichiro
Published: April 2023

PDF file - 5754K, Effects of LLP-3 on cell cycle progression (related to Figure 4)
Supplementary Figure 4 from Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model
Authors: Morales-Kastresana Aizea , Sanmamed Miguel F. , Rodriguez Inmaculada , Palazon Asis , Martinez-Forero Ivan , Labiano Sara , Hervas-Stubbs Sandra , Sangro Bruno , Ochoa Carmen , Rouzaut Ana , Azpilikueta Arantza , Bolaños Elixabet , Jure-Kunkel Maria , Gütgemann Ines , Melero Ignacio
Published: April 2023

PDF file - 1620K, Combo3 treatment induces infiltrates of blastic T lymphocytes and increases the CD8/Treg ratio.
Supplementary Figure 4 from Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex
Authors: Guvenc Hacer , Pavlyukov Marat S. , Joshi Kaushal , Kurt Habibe , Banasavadi-Siddegowda Yeshavanth K. , Mao Ping , Hong Christopher , Yamada Ryosuke , Kwon Chang-Hyuk , Bhasin Deepak , Chettiar Somsundaram , Kitange Gaspar , Park In-Hee , Sarkaria Jann N. , Li Chenglong , Shakhparonov Mihail I. , Nakano Ichiro
Published: April 2023

PDF file - 4116K, Effects of LLP-3 on the downstream target of Ran, TPX2 (related to Figure 4)
Supplementary Figure 2 from Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model
Authors: Morales-Kastresana Aizea , Sanmamed Miguel F. , Rodriguez Inmaculada , Palazon Asis , Martinez-Forero Ivan , Labiano Sara , Hervas-Stubbs Sandra , Sangro Bruno , Ochoa Carmen , Rouzaut Ana , Azpilikueta Arantza , Bolaños Elixabet , Jure-Kunkel Maria , Gütgemann Ines , Melero Ignacio
Published: April 2023

PDF file - 4662K, Three week old mice present established multifocal hepatocellular carcinomas and neonatal mice express OVA mRNA in their livers.
Supplementary Figure 1 from Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex
Authors: Guvenc Hacer , Pavlyukov Marat S. , Joshi Kaushal , Kurt Habibe , Banasavadi-Siddegowda Yeshavanth K. , Mao Ping , Hong Christopher , Yamada Ryosuke , Kwon Chang-Hyuk , Bhasin Deepak , Chettiar Somsundaram , Kitange Gaspar , Park In-Hee , Sarkaria Jann N. , Li Chenglong , Shakhparonov Mihail I. , Nakano Ichiro
Published: April 2023

PDF file - 16609K, Immunohistochemistry of Survivin and Ran (related to Figure 1)
Supplementary Table S2 from T-cell Responses to Oncogenic Merkel Cell Polyomavirus Proteins Distinguish Patients with Merkel Cell Carcinoma from Healthy Donors
Authors: Lyngaa Rikke , Pedersen Natasja Wulff , Schrama David , Thrue Charlotte Albæk , Ibrani Dafina , Met Özcan , thor Straten Per , Nghiem Paul , Becker Jürgen C. , Hadrup Sine Reker
Published: April 2023

XLSX file 42K, In silico epitope prediction
Supplementary Figure 6 from ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals
Authors: Shimada Keiji , Fujii Tomomi , Tsujikawa Kazutake , Anai Satoshi , Fujimoto Kiyohide , Konishi Noboru
Published: April 2023

PDF file, 75K, The role of ALKBH3 in progression of human urinary bladder cancer. ALKBH3 contributes to cancer cell survival, angiogenesis and invasion through manipulating upregulating NOX2-ROS signal and Tweak/Fn14-VEGF signal in not only cancer cells but also endothelial cells.
Supplementary Figure 3 from ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals
Authors: Shimada Keiji , Fujii Tomomi , Tsujikawa Kazutake , Anai Satoshi , Fujimoto Kiyohide , Konishi Noboru
Published: April 2023

PDF file, 182K, The immunohistochemistry data for Tweak/Fn14 in human urothelial carcinomas of the urinary bladder indicate a correlation with pathological parameter.
Supplementary Figure 2 from ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals
Authors: Shimada Keiji , Fujii Tomomi , Tsujikawa Kazutake , Anai Satoshi , Fujimoto Kiyohide , Konishi Noboru
Published: April 2023

PDF file, 208K, The immunohistochemistry data for ALKBH3 in human urothelial carcinomas of the urinary bladder indicate a correlation with pathological parameter.
Supplementary Figure 1 from ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals
Authors: Shimada Keiji , Fujii Tomomi , Tsujikawa Kazutake , Anai Satoshi , Fujimoto Kiyohide , Konishi Noboru
Published: April 2023

PDF file, 159K, Tweak contributes to cancer angiogenesis via stabilization of Fn14 on endothelial cells.
Supplementary Figure 1 from Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
Authors: Rader JulieAnn , Russell Mike R. , Hart Lori S. , Nakazawa Michael S. , Belcastro Lili T. , Martinez Daniel , Li Yimei , Carpenter Erica L. , Attiyeh Edward F. , Diskin Sharon J. , Kim Sunkyu , Parasuraman Sudha , Caponigro Giordano , Schnepp Robert W. , Wood Andrew C. , Pawel Bruce , Cole Kristina A. , Maris John M.
Published: April 2023

Supplementary Figure 1 - PDF file 56K, Expression of CDK4, CDK6, CCND1, and RB1 in neuroblastoma patients. Expression analysis of neuroblastoma primary tumors demonstrates that CDK4 expression, and to a lesser extent RB1 expression, is higher in high-risk neuroblastoma patients than in low risk patients
Supplementary Table 3 from The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5′ and 3′ Portions of ALK Transcripts to Detect ALK Rearrangements in Lung Cancers
Authors: Wang Rui , Pan Yunjian , Li Chenguang , Hu Haichuan , Zhang Yang , Li Hang , Luo Xiaoyang , Zhang Jie , Fang Zhaoyuan , Li Yuan , Shen Lei , Ji Hongbin , Garfield David , Sun Yihua , Chen Haiquan
Published: April 2023

PDF file, 38K, Sensitivity and specificity of different primer sets using FISH as the gold standard.
Supplementary Figure 1 from The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5′ and 3′ Portions of ALK Transcripts to Detect ALK Rearrangements in Lung Cancers
Authors: Wang Rui , Pan Yunjian , Li Chenguang , Hu Haichuan , Zhang Yang , Li Hang , Luo Xiaoyang , Zhang Jie , Fang Zhaoyuan , Li Yuan , Shen Lei , Ji Hongbin , Garfield David , Sun Yihua , Chen Haiquan
Published: April 2023

PDF file, 8019K, Heatmaps of normalized Exon Array expression values for ALK in lung adenocarcinomas.
Supplementary Figure Legends from The Nedd8-Activating Enzyme Inhibitor MLN4924 Thwarts Microenvironment-Driven NF-κB Activation and Induces Apoptosis in Chronic Lymphocytic Leukemia B Cells
Authors: Godbersen J. Claire , Humphries Leigh Ann , Danilova Olga V. , Kebbekus Peter E. , Brown Jennifer R. , Eastman Alan , Danilov Alexey V.
Published: April 2023

PDF file - 94KB
Supplementary Figure 3 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Thwarts Microenvironment-Driven NF-κB Activation and Induces Apoptosis in Chronic Lymphocytic Leukemia B Cells
Authors: Godbersen J. Claire , Humphries Leigh Ann , Danilova Olga V. , Kebbekus Peter E. , Brown Jennifer R. , Eastman Alan , Danilov Alexey V.
Published: April 2023

PDF file - 107KB, MLN4924-induced apoptosis is accompanied by loss of canonical NFkappaB activation. CLL cells were co-cultured with CD40L-expressing stroma for 24 hours in the presence or absence of 10 ng/ml IL4. Thereafter, cell were incubated with 1 microM MLN4924 for 24 hours and immunostained with p65 and cleaved PARP antibodies. Nuclei were counterstained with 4,6-diamino-2-phenylindole. A representative case (out of 3) is shown.
Supplementary Figure 3 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Thwarts Microenvironment-Driven NF-κB Activation and Induces Apoptosis in Chronic Lymphocytic Leukemia B Cells
Authors: Godbersen J. Claire , Humphries Leigh Ann , Danilova Olga V. , Kebbekus Peter E. , Brown Jennifer R. , Eastman Alan , Danilov Alexey V.
Published: April 2023

MLN4924-induced apoptosis is accompanied by loss of canonical NFÃŽÂºB activation. CLL cells were co-cultured with CD40L-expressing stroma for 24 hours in the presence or absence of 10 ng/ml IL4. Thereafter, cell were incubated with 1 ÃŽÂ¼M MLN4924 for 24 hours and immunostained with p65 and cleaved PARP antibodies. Nuclei were counterstained with 4,6-diamino-2-phenylindole. A representative case (out of 3) is shown.
Supplementary Table 1 from Castration Therapy Results in Decreased Ku70 Levels in Prostate Cancer
Authors: Al-Ubaidi Firas L. T. , Schultz Niklas , Loseva Olga , Egevad Lars , Granfors Torvald , Helleday Thomas
Published: April 2023

PDF file - 75K, Mean value for parameters used in this study for the two groups of chemically and surgically castrated patients.
Supplementary Methods from Phase I Study of Aurora A Kinase Inhibitor MLN8237 in Advanced Solid Tumors: Safety, Pharmacokinetics, Pharmacodynamics, and Bioavailability of Two Oral Formulations
Authors: Dees E. Claire , Cohen Roger B. , von Mehren Margaret , Stinchcombe Thomas E. , Liu Hua , Venkatakrishnan Karthik , Manfredi Mark , Fingert Howard , Burris Howard A. , Infante Jeffrey R.
Published: April 2023

PDF file, 76K.
Supplementary Table 2 from Overcoming the Response Plateau in Multiple Myeloma: A Novel Bortezomib-Based Strategy for Secondary Induction and High-Yield CD34+ Stem Cell Mobilization
Authors: Niesvizky Ruben , Mark Tomer M. , Ward Maureen , Jayabalan David S. , Pearse Roger N. , Manco Megan , Stern Jessica , Christos Paul J. , Mathews Lena , Shore Tsiporah B. , Zafar Faiza , Pekle Karen , Xiang Zhaoying , Ely Scott , Skerret Donna , Chen-Kiang Selina , Coleman Morton , Lane Maureen E.
Published: April 2023

PDF file - 72K, Most common all-grade and grade ≥3 AEs during DoVeD induction and bortezomib-based stem cell mobilization.
Supplementary Figure 3 from hTERT Inhibition Triggers Epstein–Barr Virus Lytic Cycle and Apoptosis in Immortalized and Transformed B Cells: A Basis for New Therapies
Authors: Giunco Silvia , Dolcetti Riccardo , Keppel Sonia , Celeghin Andrea , Indraccolo Stefano , Dal Col Jessica , Mastorci Katy , De Rossi Anita
Published: April 2023

PDF file - 69K, hTERT inhibition promotes AKT1/FOXO3/NOXA-dependent apoptosis.
Supplementary Figure Legends from Downregulation of Hematopoietic MUC1 during Experimental Colitis Increases Tumor-Promoting Myeloid-Derived Suppressor Cells
Authors: Poh Tze Wei , Madsen Cathy S. , Gorman Jessica E. , Marler Ronald J. , Leighton Jonathan A. , Cohen Peter A. , Gendler Sandra J.
Published: April 2023

Supplementary figure legends -PDF file 60K, Supplementary figure legends
Supplementary Figure 1 from Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer
Authors: Aruga Atsushi , Takeshita Nobuhiro , Kotera Yoshihito , Okuyama Ryuji , Matsushita Norimasa , Ohta Takehiro , Takeda Kazuyoshi , Yamamoto Masakazu
Published: April 2023

PDF File - 111K, Immunologic monitoring of each peptide-specific T cell response in each patient.
Supplementary table 5 from Altered DNA Methylation Landscapes of Polycomb-Repressed Loci Are Associated with Prostate Cancer Progression and ERG Oncogene Expression in Prostate Cancer
Authors: Kron Ken , Trudel Dominique , Pethe Vaijayanti , Briollais Laurent , Fleshner Neil , van der Kwast Theodorus , Bapat Bharati
Published: April 2023

Supplementary table 5 XLSX file 337K, Functional annotation of significant DMRs from ERG stratified, GS assocaited analysis using DAVID
Supplementary table 3 from Altered DNA Methylation Landscapes of Polycomb-Repressed Loci Are Associated with Prostate Cancer Progression and ERG Oncogene Expression in Prostate Cancer
Authors: Kron Ken , Trudel Dominique , Pethe Vaijayanti , Briollais Laurent , Fleshner Neil , van der Kwast Theodorus , Bapat Bharati
Published: April 2023

Supplementary table 3 XLSX file 76K, Significant DMRs in the ERG positive vs. ERG negative, ERG negative/GS associated, and ERG positive GS associated analyses
Supplementary Table 1 from Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
Authors: Gadji Macoura , Adebayo Awe Julius , Rodrigues Prerana , Kumar Rajat , Houston Donald S. , Klewes Ludger , Dièye Tandakha Ndiaye , Rego Eduardo Magalhães , Passetto Roberto Falcão , de Oliveira Fábio Morato , Mai Sabine
Published: April 2023

PDF file, 73KB, Clinical data of patients with MDS diagnosis and cytogenetic karyotypes.
Supplementary Text from DNA Topoisomerase III Alpha Regulates p53-Mediated Tumor Suppression
Authors: Hsieh Mei-Yi , Fan Jia-Rong , Chang Han-Wen , Chen Hsiang-Chin , Shen Tang-Long , Teng Shu-Chun , Yeh Yen-Hsiu , Li Tsai-Kun
Published: April 2023

PDF file 105K, Supplementary methods and figure legends
Supplementary Table S6 from Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
Authors: Zhang Geng , He Peijun , Tan Hanson , Budhu Anuradha , Gaedcke Jochen , Ghadimi B. Michael , Ried Thomas , Yfantis Harris G. , Lee Dong H. , Maitra Anirban , Hanna Nader , Alexander H. Richard , Hussain S. Perwez
Published: April 2023

Supplementary Table S6 - PDF file 70K, Correlation analysis between lipase gene surrogates and 8 fatty acids in both test and validation cohorts of PDAC
Supplementary Figure 3 from The CXCL12–CXCR4 Chemokine Pathway: A Novel Axis Regulates Lymphangiogenesis
Authors: Zhuo Wei , Jia Lin , Song Nan , Lu Xin-an , Ding Yanping , Wang Xiaofeng , Song Xiaomin , Fu Yan , Luo Yongzhang
Published: April 2023

PDF file - 1MB, AMD3100 inhibits the CXCL12-induced migration of hLECs
Supplementary Figure 5 from CD133+ Tumor Initiating Cells in a Syngenic Murine Model of Pancreatic Cancer Respond to Minnelide
Authors: Banerjee Sulagna , Nomura Alice , Sangwan Veena , Chugh Rohit , Dudeja Vikas , Vickers Selwyn M. , Saluja Ashok
Published: April 2023

PDF file - 614KB, Illumina microarray for CD133+ and CD133- cells.
Supplementary Figure S5 from Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Authors: Martin Eric S. , Belmont Peter J. , Sinnamon Mark J. , Richard Larissa Georgeon , Yuan Jing , Coffee Erin M. , Roper Jatin , Lee Lydia , Heidari Pedram , Lunt Sophia Y. , Goel Gautam , Ji Xiadong , Xie Zhi , Xie Tao , Lamb John , Weinrich Scott L. , VanArsdale Todd , Bronson Roderick T. , Xavier Ramnik J. , Vander Heiden Matthew G. , Kan Julie L. C. , Mahmood Umar , Hung Kenneth E.
Published: April 2023

PDF file - 168 KB, siKras in AP and AKP cell lines
Supplementary Methods from Phase I Pharmacokinetic/Pharmacodynamic Study of MLN8237, an Investigational, Oral, Selective Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
Authors: Cervantes Andres , Elez Elena , Roda Desamparados , Ecsedy Jeffrey , Macarulla Teresa , Venkatakrishnan Karthik , Roselló Susana , Andreu Jordi , Jung JungAh , Sanchis-Garcia Juan Manuel , Piera Adelaida , Blasco Inma , Maños Laura , Pérez-Fidalgo José-Alejandro , Fingert Howard , Baselga Jose , Tabernero Josep
Published: April 2023

PDF file, 55K.
Supplementary Methods from NADPH Oxidases as Therapeutic Targets in Chronic Myelogenous Leukemia
Authors: Sánchez-Sánchez Beatriz , Gutiérrez-Herrero Sara , López-Ruano Guillermo , Prieto-Bermejo Rodrigo , Romo-González Marta , Llanillo Marcial , Pandiella Atanasio , Guerrero Carmen , Miguel Jesús F. San , Sánchez-Guijo Fermín , del Cañizo Consuelo , Hernández-Hernández Angel
Published: April 2023

PDF file - 287KB
Supplementary Tables 1 - 5 from P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice
Authors: Tang Seng Chuan , Sparidans Rolf W. , Cheung Ka Lei , Fukami Tatsuki , Durmus Selvi , Wagenaar Els , Yokoi Tsuyoshi , van Vlijmen Bart J.M. , Beijnen Jos H. , Schinkel Alfred H.
Published: April 2023

PDF file - 110KB, S1. Overview of the corresponding deltaCt values belonging to the RT-PCR results as shown in Supplementary Data 2. S2. Overview of the corresponding ΔCt values belonging to the RT-PCR results as shown in Figure 4. S3. Overview of the corresponding deltaCt values belonging to the RT-PCR results for the knockdown experiment as shown in Figure 5. S4. Pharmacokinetic parameters, liver concentration, brain concentration and brain-to-liver ratio of everolimus in siNEG- or siCes1c-injected male Abcb1a/1b(-/-) mice receiving a single oral dose of everolimus (2 mg/kg). S5. Pharmacokinetic parameters of everolimus in blood of wild-type, Abcb1a/1b(-/-), Cyp3a(-/-) and Abcb1a/1b. Cyp3a(-/-) mice receiving oral everolimus (2 mg/kg).
Figure S8 from Adrenomedullin Blockade Suppresses Growth of Human Hormone–Independent Prostate Tumor Xenograft in Mice
Authors: Berenguer-Daizé Caroline , Boudouresque Françoise , Bastide Cyrille , Tounsi Asma , Benyahia Zohra , Acunzo Julie , Dussault Nadège , Delfino Christine , Baeza Nathalie , Daniel Laurent , Cayol Mylène , Rossi Dominique , El Battari Assou , Bertin Denis , Mabrouk Kamel , Martin Pierre-Marie , Ouafik L'Houcine
Published: April 2023

PDF file 392K, Vascular network stabilization and induction of lymphangiogenesis and neoangiogenesis modulated by the AM/AMR signaling pathway
Figure S7 from Adrenomedullin Blockade Suppresses Growth of Human Hormone–Independent Prostate Tumor Xenograft in Mice
Authors: Berenguer-Daizé Caroline , Boudouresque Françoise , Bastide Cyrille , Tounsi Asma , Benyahia Zohra , Acunzo Julie , Dussault Nadège , Delfino Christine , Baeza Nathalie , Daniel Laurent , Cayol Mylène , Rossi Dominique , El Battari Assou , Bertin Denis , Mabrouk Kamel , Martin Pierre-Marie , Ouafik L'Houcine
Published: April 2023

PDF file 1160K, AM is a growth factor survival for LECs
Figure S6 from Adrenomedullin Blockade Suppresses Growth of Human Hormone–Independent Prostate Tumor Xenograft in Mice
Authors: Berenguer-Daizé Caroline , Boudouresque Françoise , Bastide Cyrille , Tounsi Asma , Benyahia Zohra , Acunzo Julie , Dussault Nadège , Delfino Christine , Baeza Nathalie , Daniel Laurent , Cayol Mylène , Rossi Dominique , El Battari Assou , Bertin Denis , Mabrouk Kamel , Martin Pierre-Marie , Ouafik L'Houcine
Published: April 2023

PDF file 45K, {alpha}AM inhibits AM-mediated functions on LECs in vitro