bluuebunny/crossref_metadata_2025 huggingface dataset:
A (RE)DISTRIBUIÇÃO DO ISS NAS OPERAÇÕES DE CARTÕES DE CRÉDITO E DÉBITO COMO ESTRATÉGIA PARA O FEDERALISMO COOPERATIVO E AUTONOMIA MUNICIPAL
Authors: Hermany Ricardo , Da Rosa Sauzem Machado Betieli
Published: April 2021

O presente artigo centra-se em examinar a Lei Complementar (LC) n° 116/2003 e as respectivas mudanças trazidas pela LC n° 157/2016 para a cobrança, recebimento e repasse dos valores referentes ao Imposto Sobre Serviços (ISS) dos cartões de crédito e débito, também busca analisar a Ação Direta de Inconstitucionalidade (ADI) n° 5835, a qual tramita no Supremo Tribunal Federal. Justifica-se a pesquisa pela necessidade de diminuir a dependência financeira e proporcionar o aumento das receitas dos governos locais. Assim, o problema da pesquisa evidencia a seguinte indagação: como as alterações da LC n° 116/2003, que preveem a (re)distribuição do ISS nas operações de cartões de crédito e débito podem auxiliar no fortalecimento do federalismo cooperativo e autonomia municipal? A pesquisa utiliza o método de procedimento bibliográfico e aplica o método de abordagem dedutiva. Portanto, visando responder o problema da pesquisa, dividiu-se a investigação: primeiro, aborda-se o pacto federativo brasileiro com um estudo voltado ao princípio da subsidiariedade e os desafios da autonomia financeira nos municípios. No segundo, faz-se a análise do regramento do ISS e da possível guerra fiscal entre os municípios. Por fim, verifica-se a nova lei do ISS, com um estudo voltado para as inovações e analisa-se a ADI n° 5835. A partir dessas premissas conclui-se que, ao analisar o novo regramento do ISS há um aumento significativo nas receitas arrecadadas diretamente pelos entes locais, o que diminui, em parte, a dependência dos repasses intergovernamentais e a maior concretização de suas competências.
TARIFA SOCIAL DE ENERGIA ELÉTRICA: UMA REVISÃO DE LITERATURA
Authors: Félix Daniel Da Silva , Teixeira Lucas Emannuel Silva , Cançado Airton Cardoso
Published: April 2021

A Tarifa Social de Energia Elétrica, nos moldes atuais, se constitui em um significativo instrumento para universalização e democratização do fornecimento e consumo de energia elétrica. Este artigo tem como objetivo revisar a literatura e a evolução normativa sobre a Tarifa Social de Energia Elétrica (TSEE) no Brasil, buscando compreender a contribuição da TSEE a partir dos critérios de elegibilidade dessa política de energia elétrica. Metodologicamente o trabalho preocupou-se em (re)visitar o ordenamento jurídico que normatizam o programa. Em seguida, foi realizada uma revisão integrada da literatura com artigos, dissertações e teses que tratassem sobre TSEE e seus potenciais desdobramentos. Para a coleta de dados foram utilizadas as bases eletrônicas de dados Google Acadêmico, Scopus, Scielo, Catálogo de Teses e Dissertações CAPES, de dissertações e teses, no período 13 de março de 2020 a 31 de abril de 2020, com o emprego do parâmetro de busca, o termo, “Tarifa Social de Energia Elétrica”. A revisão de literatura sugere um avanço da política pública de energia elétrica, refletido pelos critérios de elegibilidade da política e a sua contribuição na universalização do acesso às famílias de baixa renda.
PROJETO RENDA MÍNIMA DE CIDADANIA: SOLUÇÃO PARA EQUIDADE SOCIAL
Authors: Zambam Neuro José , Silveira Margarete Magda da
Published: April 2021

Esse artigo tem como objetivo geral refletir sobre o Programa de Garantia de Renda Mínima como política pública para promover o aquecimento da economia, além de contribuir para a erradicação da pobreza e redução das desigualdades sociais. Após o fracasso da política de crescimento econômico através da geração de emprego, esse programa ganhou muitos aliados e está no centro das discussões que procuram alternativas para a promoção do desenvolvimento social e econômico. Acredita-se que a garantia de uma renda mínima de cidadania é o caminho mais viável para se fazer justiça social, por meio da distribuição de renda em um Estado democrático de forma equitativa. O enfoque desse estudo consiste em corroborar os aspectos positivos do Programa de Garantia de Renda Mínima para todos os cidadãos, de forma incondicional. A base legal para implementação do programa encontra-se estabelecida na Lei nº 10.835/2004, de autoria do senador Eduardo Suplicy, sancionada pelo Presidente da República, Luís Inácio Lula da Silva, e se configura como alternativa viável para correção dos problemas econômicos e sociais. Diante do agravamento da crise econômica e social devido à PC-19, o projeto Renda Mínima é uma resposta eficiente e eficaz.
Late intraocular lens dislocation. Retrospective study
Authors:   Fyodorov Eye Microsurgery Federal State Institution, Novosibirsk Branch, Egorova E.V. , Nesterenko A.S. ,   Fyodorov Eye Microsurgery Federal State Institution, Novosibirsk Branch, Chernykh V.V. ,   Fyodorov Eye Microsurgery Federal State Institution, Novosibirsk Branch, Shcherbakova L.V. ,   Research Institute of Therapy and Preventive Medicine, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk
Published: April 2021

Purpose. To analyze the frequency, terms and risk factors of late IOL dislocation. Material and methods. A retrospective cohort study was conducted based on archival data of 70 787 cases of the senile cataracts phacoemulsifications performed in 2002–2019 years. Statistical processing of the results and Kaplan–Meier analysis were performed using the SPSS 11.0 program (STATA). Results. 320 patients in the study group were treated for late IOL dislocation at various postoperative periods. The average age of the patients was 76.2±12.5 years at the moment of reconstruction procedure. The periods from the moment of IOL implantation to its dislocation varied from 4 months to 17.58 years, the average term was 6.95±3.67 years. IOL reposition was performed in 272 cases (85.0%) and IOL change – in 48 cases (15.0%). The leading risk factor was pseudoexfoliation syndrome detected in 239 patients (74.7%). Among other factors there was high myopia (72 patients; 22.5%), in 78 cases there were the surgery procedures between cataract surgery and IOL dislocation: glaucoma surgeries – 27 cases (8.4%), vitreal surgeries – 9 cases (2.8%), laser discission of secondary cataract – 42 cases (13.1%). The cumulative 5-, 10-, 15-, and 18- year risk of late IOL dislocation was estimated using Kaplan–Meier analysis. Conclusion. The dynamics of the number of reconstructive operations at late IOL dislocations has a tendency to increase. The average term from the IOL implantation to its dislocation was 6,95±3,67 years. The leading risk factor was pseudoexfoliation syndrome. The cumulative 5-, 10-, 15-, and 18-year risk of late IOL dislocation was 0.2; 0.7; 1.15; and 1.4%, respectively. Key words: intraocular lens, dislocation, phacoemulcification.
Comparative characteristics of the outcomes of the use of multidirectional intravitreal pharmacotherapy in the treatment of diabetic macular edema
Authors:   Ufa Research Institute of Eye Diseases, Ufa, Bikbov М.М. , Kudoyarova K.I. ,   Ufa Research Institute of Eye Diseases, Ufa, Zainullin R.M. ,   Ufa Research Institute of Eye Diseases, Ufa, Gilmanshin T.R. ,   Ufa Research Institute of Eye Diseases, Ufa
Published: April 2021

Purpose. To conduct a comparative analysis of the effectiveness of intravitreal injection of dexamethasone-containing implant and aflibercept in macular edema in patients with diabetes mellitus. Material and methods. The study involved 80 patients (80 eyes) with macular edema. The group 1 included 38 patients (38 eyes) who underwent a single intravitreal injection of dexamethasone-containing biodegradable implant «Ozurdex» in a dose of 0.7 mg according to the standard technique. In the group 2, 42 patients (42 eyes) received 5 loading doses of aflibercept with an interval of one month. All patients underwent monthly spectral optical coherence tomography (OCT) of the macular area, as well as visometry and tonometry during the observation period. Results. One month after intravitreal injection of the studied drugs in both groups, no inflammatory reactions were detected in any case. According to OCT data, cystic edema of the macular area with a tendency to decrease the thickness in the fovea was preserved. After treatment with aflibercept, the average retinal thickness in the macula was 186.4±15.1 µm, and visual acuity averaged 0.48±0.05 in 85.7% of patients. During therapy with intravitreal injection of Ozurdex, an increase in visual acuity was noted in 89.4% of patients. Conclusion. This study found that intravitreal pharmacotherapy with an angiogenesis blocker and a dexamethasone implant in patients with diabetic macular edema are comparable in its effectiveness – 85.7 and 89.4% respectively. If systematic anti-angiogenesis therapy is not possible for a number of reasons, it is advisable to use a prolonged dexamethasone implant. Key words: macular edema, intravitreal pharmacotherapy, angiogenesis inhibitor, implant with dexamethasone.
Gamma Knife stereotactic radiosurgery for intraocular retinoblastoma: a 5-year experience
Authors:   Fyodorov Eye Microsurgery Federal State Institution, Moscow, Yarovoy A.A. , Golanov A.V. ,   Burdenko Research Institute of Neurosurgery of the Russian Academy of Medical Sciences, Moscow, Ushakova T.L. ,   Blokhin National Medical Research Center of Oncology, Moscow,   Russian Medical Academy of Continuous Professional Education, Moscow, Kostyuchenko V.V. ,   Burdenko Research Institute of Neurosurgery of the Russian Academy of Medical Sciences, Moscow, Yarovaya V.A. ,   Fyodorov Eye Microsurgery Federal State Institution, Moscow, Kotova E.S. ,   Fyodorov Eye Microsurgery Federal State Institution, Moscow, Polyakov V.G. ,   Blokhin National Medical Research Center of Oncology, Moscow,   Russian Medical Academy of Continuous Professional Education, Moscow
Published: April 2021

External beam radiotherapy (EBR) remained for a long time the only method of treatment in children with recurrent and resistant retinoblastoma (RB). This method often leads to serious complications, including the occurrence of secondary malignant tumors. Currently, EBR is used as second-line (salvage) therapy. There is no data in the literature of using Gamma Knife stereotactic radiosurgery (GKRS) in RB treatment. Purpose. To present 5-year experience of using GKRS in patients with RB. Material and methods. 16 children (17 eyes) were treated using GKRS in the period from 2015 to 2019. Mean patient age was 34.7 months (range, 12–114 months). The eyes were classified as group B (n=4), C (n=1), D (n=12). 3 children had the last eye. All patients received systemic and local chemotherapy, all types of local treatment modalities before using GKRS. Recurrent and resistant RB was the indication for GKRS. Marginal 50% mean dose was 22 Gу (range, 20–24 Gу), depending on tumour type and location. Radiation doses were evaluated accounting critical eye structures and the orbit bones. Results. Complete regression was achieved in 11 patients, partial in 2. Four patients underwent enucleation after GKRS. Indications for enucleation were retinoblastoma recurrence (n=2) and vitreous hemorrhage with total retinal detachment (n=2). 13 eyes were salvaged with no signs of keratopathy, uveitis or damage of orbital and surrounding tissues during mean follow-up 30.6 months (range, 7–60 months). Сomplications of different severity occurred in 13 patients, including vitreous hemorrhage in 6 patients, which was successfully treated both conservative (n=3) and using pars plana vitrectomy with simultaneous melphalan irrigation (n=3). Conclusion. The first experience of GKRS as an alternative to enucleation in patients with RB was proved to be reasonable and successful. Key words: retinoblastoma, gamma-knife, stereotactic radiosurgery.
Prognostic and preventive role of various factors in corneal rejection after keratoplasty
Authors:   Fedorov Eye Microsurgery Federal State Institution, Krasnodar Branch, Sakhnov S.N. ,   Kuban State Medical University, Krasnodar, Myasnikova V.V. ,   Fedorov Eye Microsurgery Federal State Institution, Krasnodar Branch,   Kuban State Medical University, Krasnodar, Martsinkevich A.O. ,   Fedorov Eye Microsurgery Federal State Institution, Krasnodar Branch, Melkonyan K.I. ,   Kuban State Medical University, Krasnodar, Rusinova T.V. ,   Kuban State Medical University, Krasnodar, Yutskevich Y.A. ,   Kuban State Medical University, Krasnodar
Published: April 2021

The literature review is devoted to the analysis of modern publications on the immunological and pathogenetic mechanisms of transplanted corneal rejection, risk factors, predictors and methods of the prevention of this complication. The prevention of corneal rejection is challenging. Currently, there is no single algorithm for the predicting methods of the corneal graft rejection, so further research in this area is needed. Purpose. To assemble the current data on immunological and non-immunological predictors of postoperative complications after keratoplasty. The analysis of modern publications on the immunological and pathogenetic mechanisms of corneal transplant rejection, risk factors, predictors and methods of prevention of this complication is presented. The databases used were CyberLeninka, PubMed, and Medline. The focus was on the publications of the last 10 years. Conclusion. The data presented in the review make it possible to identify signs of corneal transplant rejection and to determine treatment in a timely manner, as well as to implement methods for preventing these complications. Key words: cornea, keratoplasty, keratograft, rejection, cytokines, ocular immune privilege.
EVALUASI PASCA HUNI ASPEK FUNGSIONAL PUSKESMAS PAL III KOTA PONTIANAK
Authors: Amalia Laili Rizki , Nurhamsyah Muhammad , Lestari Lestari
Published: April 2021

Community health center also known as Puskesmas are public healthcare facilities located across Indonesia. Puskesmas Pal III is a community health center in Pontianak which has been established and operating since 1993. A re-evaluation is required to adjust current building condition to users needs, standards, and regulations. The re-evaluation is also known as post occupancy evaluation (POE). This study uses mixed methods (qualitative and quantitative) which compare the questionnaire results from building users as respondents to theories and standards regarding Community Health Center or health facilities in general. In the process, the data analysis using this method is connected by three functional aspect variables namely zoning and layout, circulation, and dimensions. The result of the study shows that the spaces in Puskesmas Pal III have been operating properly according to its function, the relationship between spaces is considered quite comfortable and have met the minimum standard also grouped based on the same function, and the circulation in the building is also considered comfortable. Moreover, from samples that have been studied, the space layout is considered quite spacious although there is an inadequate space which is over capacity in motorcycle parking areas for visitors.
PENGEMBANGAN KAWASAN PESANTREN MODERN RAUDHATUL ULUM MERANTI
Authors: Sariman Sariman , Zain Zairin , Alhamdani M Ridha , Khaliesh Hamdil , Putro Jawas Dwijo
Published: April 2021

Raudhatul Ulum Meranti Islamic Boarding School is a da'wah institution that was established to educate the generation of Muslims in Indonesia, especially in West Kalimantan. Raudhatul Ulum Meranti Islamic Boarding School was founded in 1896 in a village called Meranti Village, Sungai Ambawang District, Kubu Raya Regency. The curriculum applied by the pesantren initially only adhered to the classical system (teaching the yellow book) and developed into a curriculum sourced from the Ministry of Religion (KEMENAG). The aim of developing the area of Raudhatul Ulum Meranti Islamic Boarding School is to make facilities suitable for the modern education system. The design location is on Jalan Muhajirin, Kampung Meranti, Puguk Village, Sungai Ambawang District, Kubu Raya Regency. The stage method in this design starts from the Idea Stage, Data Collection, Analysis, Synthesis, Pre-Design and Design Development. The concept of Natural Pro Rate is applied so the areas that are still green do not have to build by destroying nature in the area, but rather organize and maintain the natural conditions in order to remain green. The results of the development design at Raudhatul Ulum Meranti Islamic Boarding School can make the mosque building as the heart of the area. Worship and educational facilities are made with Islamic nuances by combining ornaments in the building and creating a separate area between the male and female students.
SEKOLAH TINGGI DESAIN KOMUNIKASI VISUAL DI KOTA PONTIANAK
Authors: Kurniati Elin , Rudiyono Rudiyono , Andi Uray Fery
Published: April 2021

Over the recent years, the creative economy sectors has shown rapid growth thanks to the development of digital technology in 4.0 era. Visual Communication Design is one of those sectors mentioned above. It’s proven by variant opportunities and needs of professionals in design field and similar others. However, educational facilities that organizing and producing labor in Visual Communication Design is still unavailable in Pontianak. Pontianak, Capital of West Borneo/Kalimantan which is well known as central of west kalimantan’s populations’ activites is considered as a strategic location to establish higher educational facilities for Visual Communication Design sector. Academy of Visual Communication Design in Pontianak is a tertiary education institution that organizes education in design field by providing studies related to media and communication. (especially Visual Communication Design). Throughout the education program, the academy will produce professional labors with prospects of the world of work in the field of design including: graphic designers, multimedia, visual communication, product design, illustrator, photographers, animators, web designers in Pontianak. The planning stage of the Academy using J.C. Jones model which consists of concept, data collecting, analyze, synthesize, evaluation and optimalization. Those stages aims to produce a concept to build Academy of Visual Communication Design that will able to help the development of skills and creativities of it learners in order to increase human resource qualities in Pontianak.
PUSAT KESENIAN DAYAK KALIMANTAN BARAT DI KOTA PONTIANAK
Authors: Trivaldo Hendrikus , Andi Uray Fery , Rudiyono Rudiyono
Published: April 2021

West Kalimantan is a province that has a very diverse artistic potential. West Kalimantan Province inhabited by indigenous people and other migrants. The dominant ethnic groups are Dayak, Malay and Chinese. The Dayak tribe is rich in a variety of arts, such as dance, sculpture, painting and others. Every year, the Dayak tribe holds a Dayak Gawai featuring a Dayak art competition. Dayak art was developed by a large number of art studios but not yet well-organized, so a forum for the Dayak Arts Center of West Kalimantan was needed. The purpose of designing the West Kalimantan Dayak Arts Center in Pontianak City is to produce a design for the Dayak arts center of West Kalimantan in Pontianak City as a forum that facilitates Dayak arts in West Kalimantan that reflects the characteristics of Dayak in West Kalimantan. The design method used in the Design of the Dayak Arts Center in West Kalimantan in Pontianak City consists of several stages, namely the idea stage and the data collection stage related to the design needs and the design location. The design result of the West Kalimantan Dayak Arts Center in Pontianak City is to facilitate West Kalimantan Dayak arts based on the functions of education, information, promotion and recreation which can support the activities of West Kalimantan Dayak arts and can display forms that reflect the characteristics of West Kalimantan Dayak architecture.
PADEPOKAN SENI DAN BUDAYA MELAYU KALIMANTAN BARAT
Authors: Ikhsan Muhammad , Khaliesh Hamdil , Irwin Irwin
Published: April 2021

Pontianak City has the potential for training and development of Malay cultural arts. The arts in West Kalimantan generally include dance, music, theater (folklore) and handicrafts. Special events in West Kalimantan will be the culmination of these arts and cultural performances, namely through festivals. This art can be used as a mainstay to face the ASEAN Economic Community. The final project of the Malay Art and Culture Hermitage of West Kalimantan aims to produce a special building design for Malay art and culture with the scope of cultural arts education, recreation, and tourism that can attract public interest. Design boundaries include the arts of music, dance, theater, crafts and cooking in West Kalimantan. The design method of the Malay Art and Culture Hermitage of West Kalimantan was carried out in several stages, namely ideas, data collection, identification, analysis, synthesis, and design development. The concept used in the design is based on the Facilities and Infrastructure Course and Training Institute Standards in 2017. Design analysis produces three functions, namely primary (education), secondary (administration, exhibition, performance) and tertiary (maintenance) functions. The result is that these three functions are combined in one into nine main buildings with a centralized organizational pattern of space, circular circulation, facades, and forms with Malay characteristics.
PUSAT PERBELANJAAN MODERN DI KECAMATAN PONTIANAK BARAT
Authors: Eka Sabarullah Bimo Kurniawan , Khaliesh Hamdil , Muazir Syaiful
Published: April 2021

The increase in population and economic development in Pontianak City has increased every year, and it is also in one of the districts in Pontianak City, namely West Pontianak District, which has a fairly high level of trade and services. To follow up on this, we need a container or Modern Shopping Center in West Pontianak District by providing open spaces or (open malls) so that it can accommodate consumer needs as well as enjoy open spaces. There are secondary data that provide discussion of malls, mall classification, and theories related to modern centers. The Modern Shopping Center in West Pontianak District provides an attractive design by providing a solid facade with two masses of buildings served by a sky bridge. This Modern Shopping Center in West Pontianak District is located in a trade and service location. The design method is a systematic stage, the design method used is the J.C Jones method in the Architectural Design Methods book. The stages used are the stages of ideas, information, analysis, synthesis, evaluation, and optimization. The purpose of the design is to produce a design for a Modern Shopping Center in West Pontianak District, which is able to accommodate the community in West Pontianak District by providing recreational and entertainment areas with the concept of Open Mall and providing spaces for mall visitors such as clothing and accessories retail, culinary retail, educational retail, toy retail, plant retail, sports retail, indoor activities, and outdoor activities and other supporting functions.
PERANCANGAN GEDUNG BIOSKOP DI KOTA SINTANG
Authors: Prasetyo Denny Agung , Putro Jawas Dwijo , Muazir Syaiful
Published: April 2021

One of the districts with the largest population, densest population activities, and supporting economy is Sintang District, West Kalimantan Province with a population of 413,369 people in 2018. The increase in the population of Sintang Regency every year results in a high level of work activity and affects the desire to go to entertainment, recreation and tourism places. Many places can be visited in Sintang Regency, one of which is the Bukit Kelam tour. In today's technological era, the cinema building is one of the solutions for entertainment venues, where the audience can devote all their attentions and feelings to the living picture being witnessed. Therefore, the design of the Cinema Building located in Sintang Regency is a solution to provide a forum for the community to enjoy film shows and provide a modern building concept that is inseparable from the cultural elements in Sintang Regency. The concept of layout outside and inside the building is needed as an attraction to the Cinema Building. The theater building has the appeal of a dynamic building with a rectangular shape that follows the concept of a projector with the use of wood colors to make it look more elegant. In the building, the designer added Dayak and Malay ornaments which were elements of the Cinema Building Design concept so that it was not separated from cultural elements.
PONTIANAK COFFEE SHOP
Authors: Novan Novan , Kalsum Emilya , Lestari Lestari
Published: April 2021

Pontianak as the economic center in West Kalimantan has many coffee shops spread around the city, this shows that people's interest in coffee is increasing. however, there are still very few coffee shops in Pontianak that have processing facilities, selling coffee tools and products, and there is no educational platform to provide information about coffee. Therefore, design for a coffee shop that provides facilities that can accommodate these needs. Research method for Pontianak Coffee Shop includes the stages of observation, data collecting, identification, data analysis, planning, and design concept. The design of the Pontianak Coffee Shop building is made with 3 functions, namely a commercial function, a production function, and an educational function which has supporting facilities such as processing, workshops, and sales. The building concept adopts a tropical building form, and touch of nature to the interior and exterior of the building. The concepts are applied in structural is the use of square columns, while the environmental and utility architectural concepts are in the form of balancing the use of natural and artificial energy, and using maximum of natural ventilation systems. Design results are coffee shops building that provides not only coffee but also becomes an icon for the region in particular and Pontianak in general.
PERANCANGAN HOTEL BISNIS DI KABUPATEN SINTANG
Authors: Fathurrahman Muhammad Ardi , Irwin Irwin , Khaliesh Hamdil
Published: April 2021

Business hotels are hotels that are intended for people who live for a short period of time and these hotels are usually located in the center of the city crowd, guests who come mostly for business, meetings, seminars, trade and official company events. With the development of an area, the local community and immigrants will also increase in number, such as in Sintang district which will become the capital of the blooming province of West Kalimantan to become a new province, namely the province of Kapuas Raya, which can be sure to be the center of the crowd so that it really needs a place to live for a while, such as hotels, especially business hotels, to accommodate activities aimed at doing business, so that the economy in the area is maintained. In designing this hotel, it uses a method starting from the analysis of the design function, which will be divided into four functions, namely the management function, business function, recreation function and residential function. The design of this business hotel will also introduce existing cultures in Sintang district, one of which is handicraft woven handicrafts from the Dayak tribe in Sintang district, which motivation will be applied to certain parts of the building, such as secondary skin, ceiling patterns and part of the room walls. aims to introduce one of the handcrafts of the Dayak tribe in Sintang district.
CULTURAL CENTER KABUPATEN LANDAK
Authors: Dasilelo Alef Experancio Ximenes , Kalsum Emilya , Br. Gultom Bontor Jumaylinda
Published: April 2021

Landak Regency is one of the areas in West Kalimantan that is rich in cultural heritage. Various forms of cultural heritage come from 2 large ethntic, it is Dayak and Malay ethnic. Nevertheless, all the wealth and cultural heritage has not been integrated and has a special container. From the potential and problems, it is necessary to hold a container that can shelter and accommodate all components of cultural activities in the landak regency. This refers to the Cultural Center of Landak Regency. The design method used in the design of the Cultural Center is a seven-step design method, which starts from the search for ideas, data collection, data processing, data analysis, determining concepts and deciding the design results. This method refers to an area-scale Cultural Center design whose all variants of activities will be sheltered by the composition of several building times implemented based on their functions and activities, this Cultural Center will be supported by the application of a sheath system that will be implemented through the typical patterns of culture of Landak Regency with the emphasis of the concept more to modern minimalist buildings but rich in cultural value.
MUSEUM SENI RUPA MODERN DI PONTIANAK
Authors: Aulia Rahma , Zain Zairin , Pebriano Valentinus
Published: April 2021

Museums in general are used to store, maintain, secure and utilize museum collections in the form of cultural heritage objects. Fine arts museums are appreciated through visions with visible media and have a physical form or simply presented as a show. The city of Pontianak does not yet have a place to carry out the function of this fine art museum. The museum collection focuses on modern fine art with long-term loans to the museum. There are some art enthusiasts in Pontianak but there is no place to channel this interest. The design method uses three stages. The first stage, data collection by classifying data as information and facts on a problem. The second stage, the analysis aims to analyze the data that has been obtained. The third stage is systematic and systematic by using images in the form of stages with product results, namely, planning drawings and design reports. The design of the Modern Art Museum in Pontianak uses a green architectural approach, namely building planning that seeks to minimize various harmful influences on human health and the environment. This museum has two floors divided according to functions, namely manager and visitor functions. The facade used is of the 3R type (Reduce, Reuse, Recycle), so the walls use bricks and the windows will use low e-glass material and uPVC frames. The comparison composition of 60:40 for buildings and green land follows the requirements for building a museum.
SEKOLAH DASAR BERBASIS SENTRA DI KOTA PONTIANAK
Authors: Nursyahbani Lyla , Nurhamsyah Muhammad , Lestari Lestari
Published: April 2021

Children are the future successors of the nation, so their growth and development must be maximized, especially for children in the childhood phase. Therefore, it is hoped that all parties can support the creation of a good and child-friendly environment for their development. Indonesia has a target for all regions to become a Child Friendly City/ District (KLA) by 2030. One of the KLA indicators is Child Friendly Schools (SRA), which is manifested in the implementation of a child-friendly learning process. Schools must be able to use the right learning approach for optimal child development. One method that is considered appropriate for the child's development stage is the Beyond Centers and Circle Time (BCCT) method, which in Indonesia is known as senling or short for centers and circles. The BCCT method is a learning method that is applied based on certain areas and is centered on children as learners. This method aim is to develop all aspects of multiple intelligence in early childhood through directed play by moving classes. The purpose of this is to find out how to design a BCCT based primary school using design method by J.C. Jones. The concept of space is formulated by applying textures, colors, flexible spaces and individual spaces that can support children's development.
Transmol: Repurposing Language Model for Molecular Generation
Authors: Zhumagambetov Rustam , Peshkov Vsevolod A. , Fazli Siamac
Published: April 2021

Recent advances in convolutional neural networks have inspired the application of deep learning to other disciplines. Even though image processing and natural language processing have turned out to be the most successful, there are many other areas that have benefited, like computational chemistry in general and drug design in particular. From 2018 the scientific community has seen a surge of methodologies related to the generation of diverse molecular libraries using machine learning. However, no algorithm used an attention mechanisms for de novo molecular generation. Here we employ a variant of transformers, a recent NLP architecture, for this purpose. We have achieved a statistically significant increase in some of the core metrics of the MOSES benchmark. Furthermore, a novel way of generating libraries fusing two molecules as seeds has been described.
Unlocking the Catalytic Hydrogenolysis of Chlorosilanes into Hydrosilanes with Superbases
Authors: Durin Gabriel , Berthet Jean-Claude , Nicolas Emmanuel , Cantat Thibault
Published: April 2021

The efficient synthesis of hydrosilanes by catalytic ydrogenolysis of chlorosilanes is described, using an Iridum (III) pincer catalyst. A careful selection of a nitrogen base (incl. sterically hindered guanidines and phosphazenes) can unlock the preparation of Me3SiH, Et3SiH and Me2SiHCl in high yield (up to 98%), directly from their corresponding chlorosilanes.
TO THE QUESTION OF APPEALING TO THE COURT OF RULES IN CASES OF ADMINISTRATIVE OFFENSES
Authors: Жукова Олеся Витальевна
Published: April 2021

В статье проведен сравнительный анализ особенностей рассмотрения судами общей юрисдикции и арбитражными судами дел об оспаривании постановлений о привлечении к административной ответственности. Автором проанализированы нормы процессуального законодательства, регламентирующие порядок подачи в суды документов в электронном виде по делам об обжаловании постановлений об административных правонарушениях.

The article provides a comparative analysis of the peculiarities of consideration by courts of general jurisdiction and arbitration courts of cases on challenging decisions on bringing to administrative responsibility. The author analyzes the norms of procedural legislation governing the procedure for submitting documents to courts in electronic form in cases of appealing against decisions on administrative offenses.
TAX BENEFIT: FINDING A BALANCE BETWEEN PUBLIC AND PRIVATE INTERESTS
Authors: Юстус Ольга Ивановна
Published: April 2021

Статья посвящена проблеме достижения баланса публичных и частных интересов в сфере налогообложения в условиях цифровизации и применения риск-ориентированного подхода; автором анализируется причинно-следственная связь злоупотребления субъективными гражданскими правами с ненадлежащим исполнением конституционной налоговой обязанности; обосновывается необходимость изменения налогового законодательства с учетом цифровизации налогового администрирования и применения риск-ориентированного подхода; вносится предложение о создании новой судебной концепции в целях пресечения злоупотреблений в налоговой сфере.

The article is devoted to the problem of achieving balance between public and private interests in the sphere of taxation in the context of digitization and application of the risk-based approach; the author analyses the causal relationship between the abuse of subjective civil rights and constitutional improper performance of tax obligations; the necessity of changes in tax laws, taking into account the digitalization of tax administration and application of the risk-based approach; proposal is made to create a new judicial concept in order to prevent abuses in the tax sphere.
TO THE QUESTION OF THE CONVERSION OF NATURAL SCIENCES AND LAW IN NEW REALITIES
Authors: Кувырченкова Татьяна Владимировна , Черевко Владимир Владимирович
Published: April 2021

Статья посвящена анализу проблем конвергенции естественных наук, гуманитарных наук и права. Актуальность темы подтверждается возникшими трудностями при правовом регулировании ситуации, связанной с распространением коронавирусной инфекции (COVID-2019) и введением режимов повышенной готовности. Обосновывается необходимость правового сопровождения научных исследований и прорывных научных направлений.

The article is devoted to the analysis of the problems of convergence of natural sciences, humanities and law. The relevance of the topic is confirmed by the difficulties encountered in the legal settlement of the situation related to the spread of coronavirus infection (COVID-2019) and the introduction of high alert regimes. The necessity of legal support of scientific research and breakthrough scientific directions is substantiated.
Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and BRCA1-deficient cells
Authors: Michelena Jone , Pellegrino Stefania , Spegg Vincent , Altmeyer Matthias
Published: April 2021

DNA double-strand breaks can be repaired by non-homologous end-joining or homologous recombination. Which pathway is used depends on the balance between the tumor suppressors 53BP1 and BRCA1 and on the availability of an undamaged template DNA for homology-directed repair. How cells switch from a 53BP1-dominated to a BRCA1-governed homologous recombination response as they progress through the cell cycle is incompletely understood. Here we reveal, using high-throughput microscopy and applying single cell normalization to control for increased genome size as cells replicate their DNA, that 53BP1 recruitment to damaged replicated chromatin is inefficient in both BRCA1-proficient and BRCA1-deficient cells. Our results substantiate a dual switch model from a 53BP1-dominated response in unreplicated chromatin to a BRCA1–BARD1–dominated response in replicated chromatin, in which replication-coupled dilution of 53BP1’s binding mark H4K20me2 functionally cooperates with BRCA1–BARD1–mediated suppression of 53BP1 binding. More generally, we suggest that appropriate normalization of single cell data, for example, to DNA content, provides additional layers of information, which can be critical for quantifying and interpreting cellular phenotypes.
The Current Situation and Optimization Strategy of Paper Books Utilization in University Library
Authors: Xie Weiguo
Published: April 2021

Paper books and documents are the main media of information service in most university libraries. In order to study the main reasons for the decline of the utilization rate of paper books in university libraries, this paper takes a well-known university library in China as an example, discusses the current situation of its low utilization rate of paper books and the reasons for the problems, and puts forward relevant optimization strategies, so as to promote the improvement of the construction quality of university libraries in China.
An Analysis of American Multiculturalism
Authors: Chen Lanxi
Published: April 2021

Multiculturalism has received fierce controversy and discussion upon its proposal for its complexity in definition and in practice. This research discusses the definition of multiculturalism focusing on the comparison between the term “cultural pluralism” and “multiculturalism”, its influence on American society and its distinct characteristics, which is the claims of equality and identification between different cultures. It is argued that multiculturalism is not only a cultural ideology and a cultural war between the WASP-based mainstream culture and the cultures of the disadvantaged groups, but also a political and economic movement. The research also analyzes the practice of multiculturalism in the fields of political participation, education, race, media and the practice of multiculturalism that targets the disabled people and women. Moreover, the problems arise during the proposal and practice of multiculturalism are presented in the research. It is argued that the relationship between multiculturalism and homogeneous culture is not contradictory but united. A mature, sustainable and energetic national culture needs to seek common ground while recognizing and reserving the differences.
An Overview of Main Theories in Cognitive Linguistics
Authors: Li Na
Published: April 2021

Cognitive linguistics is an emerging language discipline that studies language based on new philosophical and cognitive views and people's experience of the world and the perception and conceptualization of the world. This paper mainly introduces main theories of Cognitive Linguistics that aims to provide some reference for language beginners and help them to fully understand Cognitive Linguistics.
The Application of Pragmatic Theory in College English Teaching
Authors: Meng Qingyan
Published: April 2021

This paper briefly summarizes the relevant theories of pragmatics, analyzes the importance of pragmatics in College English education, probes into the application of pragmatics in College English education, and points out the measures of combining pragmatics with college English teaching.
A Competence Model to Assess and Develop Designing Competence Assessment Tool
Authors: Tra Do Huong , Linh Nguyen Thi Dieu
Published: April 2021

Studies showed that competency-based assessment improvement had generated a much greater impact on students’ achievements on standardized tests than other forms of educational activities. However, studies also indicated a number of challenges for teachers when designing competence assessment tools (CAT), especially in building assessment tasks that replicate real-life practice. There have been many different models for teachers’ assessment competencies, but the competency of designing competence assessment tools (CDCAT) was not paid much attention. In hope to develop a competency model that would serve as a supporting role in developing the CDCAT for pre-service teachers and teachers, this study used a multi-step development process to construct a teachable model that reflectived the complexity of designing assessment tools. The model consisted of 12 behavioural indicators spreading across four dimensions informed by the existing literature and empirical findings in particular contexts. To guarantee the content value of the proposed model, the research twice used the expert method by two panels. The reliability of the model was tested by analyzing the data collected from the survey with students. Interesting findings were met, and the outlined CDCAT model assisted pre-service teachers in solving issues related to their assessment competence. The model was intended for educational researchers, educators, teachers, and policy makers to support teachers’ assessment competence concerning the current accountability model across educational systems. Specific implications for developing pre-service teachers' CDCAT were discussed, followed by suggestions for future studies.
Efektivitas Pelatihan Contextual Teaching and Learning (CTL) Guna Meningkatkan Kompetensi Pedagogik Guru Sekolah Dasar di Pulau Sebatik
Authors: Fadhli Yusandi Rezki , Yoenanto Nono Hery
Published: April 2021

Competency pedagogic is the ability to manage the learning of participants learners that includes an understanding of the participant students, The design and implementation of learning , evaluation of the results of learning, and the development of the participant students to actualize various potentials that its ( Mulyasa, 2009). This study aims to determine the effectiveness of Contextual Teaching and Learning training to improve the pedagogical competence of elementary school teachers on Sebatik Island. Mechanical collection of data in the form of tool measuring scale Likert, a matter of knowledge and observation guide. Design research that is used is pretest-posttest one group design with a number of subjects as much as 30 teachers of the school base . This study uses the analysis of the Wilcoxon signed rank test. The results of the analysis of the data shows the value of significance 0.000 <0.05 which means that there are differences in the mean scores of competence pedagogic between the results of the pretest participants of the training contextual teaching and learning with the results of the posttest participant training contextual teaching and learning.
Dinamika Psikologis Menikah pada Masa Pandemi COVID-19
Authors: Alfaruqy Muhammad Zulfa , Putri Finda Kalina , Soedibyo Sara Imanuel
Published: April 2021

Penelitian bertujuan untuk memahami dinamika psikologis orang yang melangsungkan pernikahan pada masa pandemi COVID-19. Penelitian dengan pendekatan indigenous psychology ini melibatkan 266 subjek yang menikah pada masa pandemi. Data digali melalui kuesioner open-ended dan dianalisis menggunakan analisis konten. Hasil menunjukkan bahwa stressor berupa peluang penolakan akad nikah dan peluang penularan virus memunculkan dominasi emosi negatif (65,54%), seperti takut, cemas, dan sedih sebelum prosesi pernikahan. Guna meredam stressor tersebut, maka diterapkanlah protokol kesehatan yaitu memakai masker, mencuci tangan, menjaga jarak, menggunakan sarung tangan, membatasi jumlah tamu, serta mengecek suhu tubuh. Dominasi emosi positif (95,22%), seperti bahagia, lega, syukur, dan tenang terasa setelah pernikahan terlaksana. Mayoritas subjek (79,70%) puas atas prosesi pernikahan karena acara berjalan lancar, khidmat, dan sesuai protokol kesehatan. Penelitian berimplikasi pada urgensi kepatuhan semua pihak terhadap norma sosial serta adaptasi harapan personal, termasuk perihal pernikahan, di tengah situasi yang penuh ketidakpastian.
Efektivitas Modifikasi Perilaku Melalui Teknik Token Ekonomi Untuk Menurunkan Perilaku Conduct Disorder pada Remaja Putri
Authors: Rakhmawati Dini , Nashori Fuad , Uyun Qurotul
Published: April 2021

There is a lot of research about the Conduct Disorders in male subjects, but research on the Conduct Disorders in female subjects relatively minimal. The purpose of this study is to reveal the effectiveness of behavior modification to reduce Conduct Disorders behaviour in adolescent girls using token economy techniques. Research conducted on a teenager who suffered Conduct Disorders antisocial types, female, 16 years old, had no formal education, have a level of intelligence below the average. With single-subject research design with ABA-type single-factor baseline, the reduction behavior seen from a comparison between the results of the test before and after the intervention. The results showed a decrease in the aspect of aggressive behavior (14 points), attention problems (11 points), deliquent behavior (10 points), withdrawn (10 points), social problems (5 points), anxiety/depression (4 points) , thought problems (1 point), and somatic complaints (0 points). Thus the behavior modification using token economy technique effective to decrease the Conduct Disorders in adolescent girls.
MONITORING CHANGES IN SELECTION CRITERIA CHARACTERISTICS OF ROMANOV SHEEP BREED
Authors:   Federal Williams Research Center of Forage Production & Agroecology, Yaroslavl Scientifi c Research Institute of livestock breeding and forage production, BARYSHEVA M.S. , KOSTYLEV M.N.
Published: April 2021

The article considers the results of selection and genetic assessment, changes in the selection potential, as well as the degree of realization of the genetic potential of animal productivity in breeding farms that breed Romanov sheep on the territory of the Russian Federation.
DYNAMICS OF BODY WEIGHT AND HEMATOLOGICAL INDICATORS OF BLOOD OF ROMANOV LAMBS AT VARIOUS LEVELS OF FEEDING
Authors:   LLC Farm Pokrov, Tver region, KHODOV A.S. , DVALISHVILI V.G. ,   L.K. Ernst Federal Science Center for Animal Husbandry
Published: April 2021

The dynamics of the body weight of sheepand lambs of the Romanov breed at the age of 3-10 months with diff erent levels of feeding (energy and protein), as well as blood biochemical parameters characterizing nitrogenous and energy metabolism are shown. With an increase in the level of metabolic energy and crude protein in the diets, nitrogen and energy metabolism of young animals proceeded more intensively.