bluuebunny/crossref_metadata_2025 huggingface dataset:
PENDAPATAN DAERAH TERHADAP PERTUMBUHAN EKONOMI PROPINSI DKI JAKARTA: BELANJA MODAL SEBAGAI PEMEDIASI
Authors: AKHADI IMAN
Published: January 2021

The objective of this research is to analyze the effect of Capital Expenditures in mediating the relationship between Regional Original Revenue and Profit Sharing Funds (Government Grant) for economic growth in DKI Jakarta Province which is measured based on the value of Gross Regional Domestic Product (GRDP) based on constant 2010 prices. Secondary data on variables comes from data on the realization of the DKI Jakarta Provincial Budget between 2013-2017. This research is a quantitative study using multiple regression analysis methods. The results of the study show that simultaneously, Local Original Income and Profit Sharing Funds have a significant effect on economic growth. Partially, only Regional Original Income has a positive effect on economic growth, whereas the Revenue Sharing Fund does not affect the economic growth of DKI Jakarta Province. The results of subsequent research indicate that Capital Expenditures do not mediate the relationship between Regional Original Revenue and Profit Sharing Funds to the economic growth of DKI Jakarta Province
A report on the postoperative outcome of MyIOL603YP implantation in Hospital Melaka
Authors: Kalaichelvam Khavigpriyaa
Published: January 2021

This study reports the experience and outcomes of a new monofocal intraocular lens (IOL) by the name of MyIOL603YP. The performance of MyIOL603YP over a 2-month follow-up period from June to December 2016 was assessed. Twenty-nine patients, one eye from each patient, were recruited by convenience sampling method and were evaluated prospectively. Patients who were eligible to receive welfare IOLs were chosen. Detailed, preoperative examination was done, and the surgical procedure was the same for all, which was phacoemulsification with MyIOL603YP implantation with random surgeon selection. Intraoperative complications were recorded by the surgeon. Postoperative examination was done during follow-up at one week and two months post cataract operation.Results were obtained from 22 eyes (7 defaulted). Twenty eyes (84.7%) achieved an unaided postoperative visual acuity of 6/12 or better. There were no intraoperative or postoperative complications. There was no reported inflammation two months after cataract surgery with implantation of MyIOL603YP and no posterior capsule opacification was reported.
23-G trocar-assisted cyclopexy: scleral sparing method as a new modality for large cyclodialysis repair
Authors: En Yoo Ivan Cheng , Hsien Yong Meng , Mustapha Mushawiahti , Hamzah Jemaima Che
Published: January 2021

Cyclodialysis cleft results from separation of longitudinal ciliary muscle fibres from the scleral spur. The separation increases the uveoscleral outflow, leading to severe hypotony. Complexity in managing such condition relies on the extent of the injury and its collateral damage. We reported an alternative method of surgical repair for large cyclodialysis. The procedure was less invasive utilizing a scleral sparing technique. A 66-year-old gentleman presented with severe blunt trauma injury to the globe secondary to shuttlecock injury while playing badminton. He presented with a vision of hand motion. There was hyphaema (filling up half of the anterior chamber), complete posterior dislocation of the crystalline lens, and minimal vitreous haemorrhage. Posterior globe rupture was excluded with further imaging of the orbit. Despite significant amount of hyphaema, intraocular pressure (IOP) remained low several days post injury. Further investigations revealed the presence of almost 270° of cyclodialysis. Surgical repair was indicated. In order to avoid an extensive cut on the sclera, the treating surgeon decided to explore a less invasive method utilizing a small gauge vitrectomy trocar. The main instruments used were the trocar, a straight prolene needle, and a bent 25-G needle. The direction of trocar insertion plays a pivotal role in bringing the detached ciliary body back to its original position. The simplified technique did not require the creation of a scleral flap or direct visualization of the ciliary body. The technique was fast and less invasive, with early improvement of IOP post intervention.
Comparing the Lenstar Optical Biometer and the Verion Image-Guided System for intraocular lens power calculation
Authors: Lee Mun Wai
Published: January 2021

Introduction: This study aims to evaluate the accuracy of the measurement parameters of the new Verion Image Guided System compared with an established standard of care.

Purpose: To compare the keratometry (K) and white-to-white (WTW) measurements obtained from the Lenstar Optical Biometer (LS) with those from the Verion Image-Guided System (VR) and their effect on intraocular lens (IOL) power calculation.

Design: Prospective comparative case series.

Materials and methods: Sixty patients going for cataract surgery had biometry measurements and IOL calculation with the LS. Axial length from LS was used together with K and WTW measurements from VR for IOL calculation as well. IOL selection was done using the Barrett Universal II formula targeting emmetropia. The prediction error (PE) within 0.25 D, 0.5 D, and 1 D of refractive target and the mean absolute error (MAE) were calculated for both the LS and VR.

Results: Keratometry measurements and steep axis from the VR were closely correlated with the LS (Pearson correlation coefficient K1, r = 0.958; K2, r = 0.952; axis, r = 0.950). The WTW measurements were less so (WTW, r = 0.471). The MAE was 0.317 and 0.347 for LS and VR, respectively. PE within 0.25 D was 48.3% and 40%; within 0.5 D was 83.3% and 76.7%; and within 1 D was 98.3% and 96.7% for LS and VR, respectively. There was no statistically significant difference in MAE between the LS and VR (p = 0.74)

Conclusion: Using the K and WTW measurements from the Verion Image-Guided System for IOL power calculation did provide comparable results with the Lenstar. The Lenstar had a higher proportion of eyes within 0.5 D of refractive target but the difference was not statistically significant.
Comparison of contrast sensitivity between three aspheric acrylic monofocal intraocular lenses: a prospective randomised trial
Authors: Alice Chin Chiet Ying , Gurusamy Banumathi , Andrew Lim Keat , Bastion Mae-Lynn Catherine
Published: January 2021

Introduction: Evolution of cataract surgery and implantation of intraocular lenses (IOL) with new technological designs to optimise functional vision has been the aim of cataract surgery today. Aspherical lens design is a new lens technology to counteract spherical aberration exerted by a conventional IOL.

Purpose: To compare the contrast sensitivity after cataract surgery between aspheric IOLs with negative spherical aberration (Tecnis ZA9003TM and AcrySof IQTM) and zero spherical aberration IOLs (Akreos Adapt Advance Optic [AO]TM).

Study design: Interventional, single-blinded, randomised controlled trial.

Methods: Ninety-six patients were recruited with 32 eyes in each study arm. All patients underwent standard phacoemulsification with implantation of an aspheric acrylic IOL randomised to one of the three lens models by a single experienced surgeon. Pre- and postoperative contrast sensitivity was analysed using the CSV1000E chart under photopic and mesopic conditions with and without glare testing.

Results: All three lenses showed statistically significant improvement in contrast sensitivity postoperatively at all spatial frequencies under photopic, mesopic, and scotopic conditions with glare. There was no statistically significant difference between the groups. Tecnis ZA9003TM showed marked improvement in mesopic contrast sensitivity at 18 cycles/degree (cpd) at 12 weeks (p < 0.05). The zero aberration Akreos Adapt AOTM showed better photopic contrast sensitivity compared to mesopic contrast sensitivity (p > 0.05).

Conclusion: AcrySof IQTM, Akreos Adapt AOTM, and Tecnis ZA9003TM performed equally well in contrast sensitivity at all spatial frequencies under photopic and mesopic conditions with and without glare testing. All lenses had statistically significant improvement in contrast sensitivity after cataract surgery. The negative aberration IOL Tecnis ZA9003TM showed marked improvement in mesopic contrast sensitivity at 18 cpd at 12 weeks. The zero aberration IOL, Akreos Adapt AOTM showed better photopic contrast sensitivity compared to mesopic contrast sensitivity.
Leptospira, the ocular predator
Authors: Subramaniam Sangeetha , Silim Anhar Hafiz bin , Raja Omar Raja Norliza , Che Hamzah Jemaima
Published: January 2021

Neuroretinitis is an inflammatory optic neuropathy with a classic funduscopic appearance of optic disc swelling and hard exudates on the macula in a star formation. It can be a manifestation of systemic, infectious or autoimmune disease. Here, we report three patients who presented with sudden onset of painless blurring of vision. Ophthalmic evaluation revealed a characteristic picture of neuroretinitis. Detailed study of the cases revealed leptospirosis being the aetiology of the neuroretinitis. Leptospirosis is a zoonotic infection caused by spirochetes Leptospira, which presents with both ocular and systemic manifestations. Neuroretinitis has been reported in the few cases of leptospirosis. We present three cases of leptospirosis with bilateral and unilateral neuroretinitis presenting with sudden loss of vision, optic disc oedema, and macular star. Leptospirosis was confirmed by serological test and the disease responded optimally to specific therapy. Although funduscopic examination showed marked inflammatory changes in the retina and optic nerve head, the recovery following medical treatment was remarkable.
NILAI EKONOMI PEMANFAATAN FLORA DI TAMAN NASIONAL BALURAN
Authors: Ichtiarso Joko Mulyo
Published: January 2021

One of ecosystem services that is used by buffer community village flora thatis component ecosystem at Baluran National Park (BNP). Form of flora htat isusedy by community are fruit, understrorey, tubers, and so on. This motivates tocalculate economic value of flora as component ecosystem. The object of research is to know how much economic value of ecosystem services especially from fauna in BNP which has been utized by community buffer village and dependence on BNP. The method of research by quantitative and qualitative approaches. Data collected are typological conditions of BNP community buffer village, human resources who used the services of BNP ecosystem services, identity of community who used ecosystem services, types of ecosystem services used by community, harvest season, location of ecosystem services, community income that uses ecosystem and dependence on BNP ecosystem services. The result of research are economic value of flora that is component of ecosystem that have been utilized by community buffer village are candlenut (Rp. 1,306,694,400), tamarind (Rp. 1,292,085,000), acacia (Rp. 3,951,415,200), gadung (Rp. 924,160,800), firewood (Rp. 1,409,100,000), grass (Rp. 5,154,600,000), and ramban (Rp. 72,240,000). Total economic is Rp.14,110,295,400,- per year.Keywords: Flora, Ecosystem services, Baluran National Park
DIVERSIDAD MORFOLÓGICA Y AGRONÓMICA DE MAÍCES NATIVOS DEL ALTIPLANO DE TAMAULIPAS, MÉXICO
Authors: González-Martínez Javier , Rocandio-Rodríguez Mario , Contreras-Toledo Aremi R. , Joaquín-Cancino Santiago , Vanoye-Eligio Venancio , Chacón-Hernández Julio C. , Hernández-Bautista Aurelio
Published: January 2021

El estado de Tamaulipas en México es considerado como parte de los centros de origen del maíz nativo, los maíces que ahí se cultivan poseen características agronómicas de importancia y son ampliamente diversos; sin embargo, los estudios de diversidad en el estado han sido pocos. Se analizó la diversidad morfológica y agronómica entre poblaciones de maíz nativo cultivadas en el Altiplano de Tamaulipas. Se establecieron experimentos en los municipios de Jaumave, Tula y Güémez, Tamaulipas, bajo un diseño experimental de bloques completos al azar en los ciclos de siembra otoño-invierno 2016-2017 y primavera-verano del 2017, con 98 poblaciones de maíz nativo y dos testigos. Se registraron 33 caracteres morfológicos, se sometieron a análisis de varianza combinado; la agrupación de la diversidad se realizó mediante análisis de componentes principales. El análisis de componentes principales explico el 73.96 % de la variación total y mostró que los caracteres fenológicos y de mazorca fueron los que mayormente sustentaron la variación morfológica. El análisis de conglomerados permitió la identificación de dos grandes grupos morfológicos, donde predominó la raza Ratón. La variación del maíz nativo de Tamaulipas es amplia y contínua, en la cual se podrían encontrar alelos de interés para incorporarlos a programas de mejoramiento genético de maíz.
Book Review: Tax Tyranny
Authors: Hülsmann Jörg Guido
Published: January 2021

Pascal Salin's _Tax Tyranny_ is an essay on the principles of taxation. First published in 1985 under the title _L’arbitraire fiscale,_ this first English edition is most welcome. Written in a non-technical way, it is accessible to a broad readership. It serves very well as an introductory text for undergraduates, most notably in macroeconomics or public economics, but it also carries a lot of original food for thought that deserves the attention of scholars and tax practitioners. The central thesis is that there are no rational grounds for taxation and taxation can therefore never be justified. By its very nature, the tax state can never be a just state. When it taxes its citizens, it is arbitrary and tyrannical.
La situación de la producción científica latinoamericana en el área de la Ciencia de Información Geográfica
Authors: López-Vázquez Carlos , Bernabé-Poveda Miguel Ángel
Published: January 2021

Se ha planteado el objetivo para la Revista Cartográfica de captar un mínimo de 45 artículos por año con el fin de ser considerada para ingresar en el catálogo SciELO. Para valorar lo razonable del objetivo se ha intentado por primera vez estimar el volumen de la producción científica de los países miembro del Instituto Panamericano de Geografía e Historia en el área de la Ciencia de la Información Geográfica. Se realizó un análisis bibliométrico de los artículos publicados en un conjunto representativo de revistas internacionales, filtrando aquellos cuyos autores son de países de la región. Se excluyó a los EEUU en razón de su peso relativo en el área. La principal conclusión es que el objetivo de captar parte de esos trabajos y así más que duplicar el material hoy publicado en la Revista Cartográfica parece difícil de alcanzar en un corto plazo. Como alternativa será necesario interesar a autores de fuera de la región, quienes típicamente toman primero en cuenta la categorización de la revista, categorización que aún no se ha logrado, conformándose así un círculo vicioso de difícil solución. Subsidiariamente se ha realizado un análisis discriminado por países que puede ser utilizado en el futuro para identificar grupos y líneas activas de investigación en la región.
Propuesta de una guía para la evaluación de la exactitud posicional de datos espaciales
Authors: Ariza-López Francisco Javier , García-Balboa José Luis , Robledo Ceballos Joselyn , Rodríguez-Avi José , Casanova Rosario
Published: January 2021

Los participantes en el proyecto de asistencia técnica del IPGH (PAT2018) (Agenda del IPGH 2010-2020) "Propuesta de adopción de metodologías y procedimientos para la evaluación de la calidad de la información geográfica para los Estados miembros del IPGH", decidieron abordar la realización de una propuesta de guía genérica para la evaluación de la exactitud posicional de datos espaciales. En la elaboración de la propuesta de guía se han aplicado el ciclo de Deming y un método específico de desarrollo de guías basadas en evidencias. Se ha asumido su alineación con las normas internacionales de la familia ISO 19100 y con los métodos de evaluación de la exactitud posicional más extendidos en Hispanoamérica. Igualmente, se presentan los distintos alcances asumidos para su elaboración, tanto en lo que se refiere a contenidos como a la perspectiva genérica desarrollada.
Optimización del uso del paisaje físico-geográfico en las zonas funcionales de la microcuenca Potrero de la Palmita, Nayarit, México.
Authors: Valdés Carrera Alejandro César , Hernández Guerrero Juan Alfredo , Carbajal Monroy Julio César
Published: January 2021

La planeación del territorio comprendido en las zonas funcionales de una cuenca requiere un enfoque integrador y participativo, desarrollado a partir de una metodología amplia y compleja que considere las cualidades y debilidades del territorio en cuestión, para así tomar la mejor decisión con respecto al uso actual y futuro del paisaje, contemplando sus condiciones biofísicas y socio-productivas. El presente trabajo tiene como objetivo elaborar una propuesta de optimización del uso del paisaje en las zonas funcionales de la microcuenca Potrero de la Palmita, Nayarit, para contribuir a la generación de información cartográfica a escala local, a la planeación y a la gestión de su territorio. Para dar respuesta al objetivo se llevó a cabo un diagnóstico integrado que retomó los métodos de balance hídrico, cambio de uso del suelo, erosión hídrica laminar, susceptibilidad ante peligros naturales y aptitud territorial. Además, se realizó un diagnóstico participativo que consideró el método de grupos focales, talleres y SIG participativos, y finalmente, se propuso el método de optimización del uso del territorio a escala local (1:10 000). La información obtenida fue procesada por medio de una plataforma de Sistemas de Información Geográfica (SIG). El resultado fue la descripción detallada del estado socioambiental de las unidades de paisaje, con base en el cual se propusieron nueve diferentes usos del suelo (Conservación, Conservación-Turístico, Pecuario, Pecuario-Turístico, Agrícola, Agrícola-Turístico, Agropecuario, Agropecuario-Turístico y Asentamiento-Turístico). La investigación representó una metodología viable para abordar la planeación territorial a escala de gran detalle en una microcuenca, permitiendo generar estrategias de gestión, planeación y manejo, a partir de la identificación de su estado, dinámica, procesos, potenciales y problemáticas socioambientales, teniendo como principal herramienta el uso de plataformas de SIG.
Un diagnóstico de infraestructura geodésica en la región de Centroamérica y el Caribe
Authors: Avalos Naranjo David , Figueroa Carlos E. , Medrano Silva Wilmer , Ballesteros Christopher , Robles Pereira Vinicio , Alvarez Calderón Alvaro , Tavera Polanco Leopoldo , Meza Oscar
Published: January 2021

El documento presenta un sumario de la infraestructura geodésica existente en ocho países de la región Centroamericana y del Caribe. A través de mapas y tablas se ofrecen cifras actualizadas concretas sobre cantidad y ubicación de las redes de control horizontal, vertical y gravimétrico. Las agencias federales encargadas de establecer el marco de referencia oficial nacional explican características técnicas de su infraestructura y describen su visión de avance para satisfacer a usuarios co- mo topógrafos y generadores de cartografía de alta precisión. Analizando los contenidos se identificaron similitudes y discrepancias en el grado de avance entre países. Hasta el momento la infraestructura geodésica regio- nal ha logrado ser impulsada para satisfacer requerimientos mínimos de operación. Las agencias ostentan un conjunto significativo de marcas de referencia sobre el terreno y bases de datos en actualización constante. Visto esto desde una perspecti- va de avance y tendencias mundiales, puede decirse que el cubrimiento de necesi- dades futuras está comprometido debido a insuficiencias presupuestales sintomáticas que en casos han llevado a detener el avance en el control vertical y gravimétrico. Se concluye haciendo una recomendación a incentivar la capacitación especializada, desde la cual el personal de las agencias geográficas podrá producir proyectos locales hechos a la medida para equilibrar los avances en las tres vertien- tes del control geodésico.
Aplicaciones cartográficas en PEMEX
Authors: Jordá Lozano Margarita , Zúñiga Montalvo Miguel
Published: January 2021

Descripción del uso de los materiales cartográficos en Petróleos Mexicanos (PEMEX), a partir de la información, los mapas y los sistemas de información geo- gráfica institucionales, destacando las aplicaciones más importantes actualmente.
Métodos de estimación de la exactitud posicional a través de elementos lineales
Authors: Sinde González Izar
Published: January 2021

En la actualidad existen diferentes métodos desarrollados y en proceso de investi- gación que tienen como objetivo comprobar la exactitud posicional de la cartogra- fía. Los más extendidos y estandarizados son los basados en elementos puntuales (NMAS EMAS ASPRS o NSSDA), pero también existen los basados en elementos lineales e incluso superficiales. En el presente artículo se detallan cuáles son los métodos más extendidos de comprobación de la exactitud posicional con elementos lineales, qué resultados se han obtenido en algunos estudios recientes y cuáles serán las futuras líneas de investigación a seguir en esta temática. Para esta tarea, se ana- lizan casos de aplicación en diversas especialidades de la cartografía como pueden ser la cartografía costera, el catastro, vías de comunicación o simplemente el error al aplicar algún proceso de generalización a elementos lineales. Excepto la genera- lización, las demás variantes requieren obtener datos adicionales de alguna fuente más fiable. La forma en que se pueden adquirir estos datos se analizará también en este documento, ya que es aquí donde radica el mayor condicionante para la aplica- ción de las citadas metodologías. El avance de las nuevas tecnologías así como las características de las bases de datos geográficas, en las cuales predominan en gene- ral los elementos lineales, hacen de estos métodos una forma de comprobación de la exactitud posicional a tener muy en cuenta y que podría competir con las ya estan- darizadas basadas en elementos puntuales.
Catastro multipropósito sostenible: una necesidad inaplazable
Authors: Alcázar Molina Manuel-G.
Published: January 2021

El catastro multipropósito sostenible es la herramienta fundamental para consolidar al país como un territorio articulado, integrado y cohesionado en los ámbitos físico, económico y social, dentro de su entorno geográfico natural. Ello repercutirá en un desarrollo social equilibrado que mejore la calidad de vida de sus ciudadanos, esti- mulado por una mejor y más eficaz gestión de los recursos públicos. 

Pero, aun considerándolo una meta en muchas iniciativas, el catastro multipro- pósito sostenible debe contemplarse como un paso previo para lograr una verdadera infraestructura territorial, dinámica, ágil, confiable y especialmente, útil. 

En este documento se ofrece una visión pluridisciplinar de un catastro multipro- pósito, identificando aquellos parámetros que se consideran fundamentales para lograr un producto eficiente, sostenible en el tiempo y confiable. Se expone y desa- rrolla una secuencia lógica para su construcción, identificando los problemas más comunes que pueden presentarse, seguido de la exposición de soluciones para los mismos. Todo ello dentro de la independencia técnico-jurídica de cada modelo construido, destinado a satisfacer las necesidades específicas para las que se diseña, pero con una clara visión globalizadora.
Riesgo por tsunami en la ciudad de San Antonio: un aporte a gobiernos locales
Authors: Barrenechea Fabiola , Ferrada María Fernanda , Jara Moisés
Published: January 2021

La ubicación geológica de Chile, en la zona de subducción entre las Placas de Naz- ca y Sudamericana, ha hecho que los tsunamis sean recurrentes, causando una gran problemática para la población. 

El presente trabajo se basa en la propuesta de una metodología de fácil aplica- ción, que permita a los municipios costeros del país, identificar zonas de riesgo de tsunamis por medio de un Sistema de Información Geográfica, para gestionar la primera respuesta frente a una situación de emergencia. La metodología se aplicó en la Comuna de San Antonio, Región de Valparaíso. Su desarrollo contempló información de catastros de materialidad de las viviendas, modelo digital de eleva- ción y coberturas vectoriales de información socioeconómica referente a la comuna.
Value-Driven Robotic Digital Twins in Cyber-Physical Applications
Authors: Guiffo Kaigom Eric , Rossmann Juergen
Published: January 2021

To appear in IEEE Transactions on Industrial Informatics

Abstract: Although the skills of robot manipulators are becoming technically more
complex, the unprecedented cost-effective access to recently unveiled
intelligent robots has the potential to unleash as yet unimagined
automation capabilities. A key technology behind this opportunity for
companies to gain a competitive edge through an informed and intelligent
robotized automation is the robotic digital twin (RDT). As such, the
RDT will be instrumental in mirroring targeted properties of a physical
robot to obtain a digital sibling flexibly harnessed in virtual testbeds
to understand, predict, and shape the robot performance. However, these
objectives remain challenging to well-established simulators. This is
because the architectural and functional capabilities they support are
not sufficiently in-line with ever-growing and varying demands for agile
and cost-efficient manipulations. As a consequence, robot stakeholders
can hardly use RDTs to unlock opportunities and meet needs from
prospective markets. This paper contributes to addressing this gap. We
introduce a novel concept for the development of a RDT that helps create
and add value to current and future robotized cyber-physical
applications. Hereinafter referred to as the value-driven RDT (vdRDT),
it systematically captures the robot dynamics and purposefully farms
data, about which its services reason to facilitate insight and deliver
capabilities and benefits to stakeholders. Experiment results show that
vdRDTs enlarge the scope of, adapt to, and revitalize robotized
applications carried out in different fields.
Vendedores ambulantes en Cochabamba: desafían al cáncer de piel.
Authors: Orellana Aguilar Maria Lorena , Matosinho Moraes Andreyna , Mota Carla Daniela , Elfy Ayaviri Dilean
Published: January 2021

Introducción: El cáncer de piel es una afección donde se forman células cancerígenas en los tejidos de la piel. Estar expuestos a luz solar puede aumentar el riesgo de presentar cáncer de piel. El objetivo de este estudio es determinar características de riesgo y protección de los vendedores ambulantes en Cochabamba. Metodología: El trabajo presenta un diseño descriptivo, transversal, observacional y prospectivo, el cual fue realizado en los mercados populares y calles comerciales de Cochabamba. La población de estudio fue de 277 comerciantes ambulantes. Resultados: 5,8 % refieren tener familiares con antecedente de cáncer de piel, el 80,9 % indica tener conocimiento que la exposición excesiva a rayos ultravioleta genera cáncer de piel. El 28,2 % de las personas utiliza protector solar y el 71,8 % no. El tiempo de exposición a los rayos ultravioleta es; 7,2 % indica menos de 4 horas, 38,3 % 4 a 5 horas, 0,4 % de 5 a 6 horas, 49,1 % de 6 a 7 y el 5,1 % mayor a 10 horas. El 84.1 % usa indumentaria adecuada de protección contra los rayos ultravioleta y el 15.9% no. Discusión: Las radiaciones solares ejercen efectos perjudiciales sobre la piel, de modo que existe una clara relación entre la radiación ultravioleta y el cáncer de piel; se puede prevenir con educación dirigida a la población sobre dichos efectos y búsqueda activa que permita la detección temprana.
Application of Hyperbaric Therapy Following Acoustic Trauma
– Case Report
Authors: Senderowicz Sebastian , Frydrysiak Krystyna , Kikowski Łukasz
Published: January 2021

Introduction: Acoustic trauma is noise-induced hearing damage. It can occur as a result of a strong sound stimulus or explosion, which causes a pressure wave, which causes in the organism the damage of structures filled with air, e.g. tympanic membrane. Acoustic trauma has many consequences in the form of: deterioration or complete loss of hearing, tinnitus, crackling, feeling of confusion and constant fatigue, headaches and dizziness. It also has a significant impact on the quality of life – it hinders people-to-people contacts and prevents professional activities and may be the cause of depressive disorders. Acoustic trauma can be treated, among others, through the use of hyperbaric therapy, which has a wide spectrum of activity in many fields of medicine.
Aim: The aim of the study was to present the legitimacy of using oxygen treatment at increased pressure in a patient after acute acoustic trauma.
Material and method: The study was conducted at Hyperbaric Therapy Center CREATOR in Lodz (Didactic and Research Center of the Medical University of Lodz). As a research method, case study was used in an individual patient after an acoustic trauma. Using the extended interview questionnaire and analysis of available medical records.
Conclusion: Hyperbaric therapy may be a useful method in the treatment of acute acoustic trauma.
The Influence of Winter Swimming on Blood Pressure
in Middle-Aged Women
Authors: Bielec Grzegorz , Jóźwiak Natalia
Published: January 2021

Introduction: For many years, winter baths have attracted an increasing number of participants. The results of various research indicate the increase of immunity and enhancement of anti-oxidative response in winter swimmers. The relationship between winter bathing and blood pressure variation is not thoroughly explored.
Aim: The aim of the study was the evaluation of blood pressure variation in middle-aged women attending regularly in winter swimming.
Material and Methods: The study was conducted in a group of twenty five healthy women in age range 17-63 years (mean 39.9 years), who regularly participated in lake swims between October and April. The first examination was taken in December 2018, the second one in April 2019.
Duration of each immersion in the water was 4 minutes, water temperature was below 4°C. Blood pressure was measured before the immersion and immediately after getting out of the water. Body temperature was assessed before and after the swim. Control group consisted of 25 women of similar age who never practiced winter swimming.
Results: In intervention group systolic and diastolic blood pressure increased essentially after each immersion in cold water. Decrease of systolic and diastolic blood pressure was observed on spring, but these changes were not significant. Decrease of systolic blood pressure was noted in control group in April
Conclusions: In intervention group no significant influence of winter swimming on blood pressure was discovered. Further studies, considering greater number of morphological and physiological variables are needed to confirm healthy impact of winter swimming on cardio-vascular system.
INTENSIFICATION OF ANTIVIRAL THERAPY OF CHRONIC HEPATITIS B BY MEANS OF INTRADERMAL IMMUNIZATION WITH AUTOLEUKOCYTES
Authors: Zinchuk Alexandr N. , Golubovska Olga A. , Herasun Borys A. , Zadorozhnyi Andrii M. , Herasun Oleksandr B.
Published: January 2021

The aim: Was a trial of intradermal immunization with native autoleukocytes as a curative vaccine.
Materials and methods: Thus, 3-shot series vaccination by means of intradermal injection of autoleukocytes with 30 – 40 days interval was conducted for patients who, in spite of continuous (at least 2 years) therapy with nucleotide analogue, experienced HBV DNA reproduction. For this procedure, 80 – 100 ml of a patient’s heparinized venous blood was being precipitated at the temperature 37оС for 120 – 140 minutes, after blood plasma was being centrifuged at 450g for 8 minutes. The precipitate was resuspended in 1 – 1.5 ml of blood serum and injected intradermally in the region of the back.
Results: Viral load decreased in all patients even after single immunization; it was possible to achieve a negative result by ultrasensitive PCR method in 23.33% of patients in the group of patients who did not respond adequately to antiviral therapy.
Conclusions: In patients with chronic hepatitis B, intradermal immunization with autoleukocytes has a significant impact on intensity of virus replication. It is confirmed by a considerable reduction of DNA HBV amount in patients, in whom antiviral therapy was stopped before immunization
EVALUATION OF DIABETES SELF-MANAGEMENT EDUCATION IN PATIENTS WITH CONCOMITANT CHRONIC KIDNEY DISEASE
Authors: Korzh Oleksii M.
Published: January 2021

The aim: Was to evaluate the quality of DSME provided by primary care physicians to people with diabetes mellitus.
Materials and methods: A descriptive cross-sectional study was conducted among 120 primary care physicians. The quality of diabetes self-management training provided
by physicians was assessed on a personal scale of 39 Likert questions obtained from the American Association of Diabetes Educators in seven areas of diabetes self-monitoring.
The Cronbach’s reliability coefficient for each domain / subscale was ≥ 0.7. The data were analyzed using an independent selective t-test and one-way ANOVA.
Results: More than half of the doctors provided “inadequate quality” of diabetes self-management in all areas. Doctors had the highest average score in the domain of “drug
intake” (4.46 ± 0.61). Average scores in the “problem-solving domain” (3.52 ± 0.63) and “ being active domain” (3.46 ± 0.75) were low. The quality of DSME provided by
physicians was not related to any of the characteristics of the physician.
Conclusions: The quality of doctors’ communication on DSME in this study was suboptimal. Most adequately informed cases of diabetic behavior associated with self-management
have been associated with reduced risk factors and an orientation towards disease. Thus, training of primary care physicians in diabetic self-management is recommended
because of the key role that these doctors play in managing diabetes.
THE INFLUENCE OF EXOCRINE PANCREATIC INSUFFICIENCY IN THE FORMATION OF OSTEOPENIA IN PATIENTS WITH PRIMARY OSTEOARTHRITIS
Authors: Babinets Liliya S. , Halabitska Iryna M. , Borovyk Iryna O. , Redkva Olena V. , Sasyk Halyna M.
Published: January 2021

The aim: Make complex study of bone density in patients with primary osteoarthritis and exocrine pancreatic insufficiency and patients with primary osteoarthritis without
exocrine pancreatic insufficiency.
Materials and methods: There were examined 140 patients with primary osteoarthritis without exocrine pancreatic insufficiency and combination osteoarthritis and exocrine
pancreatic insufficiency. Diagnosis of osteoarthritis was based on diagnostic X-Ray criteria – according to J.H. Kellgren and J.S. Lawrence. The level of exocrine pancreatic
insufficiency was based on result of Elisa test. State of mineral bone density was examined by using dual-photon densitometry.
Results: It was established that there was a progressive, statistical, significant increase of mineral density of bone tissue in the 1-st group patients with osteoarthritis. Patients in the 2-nd group, with osteoarthritis in the comorbidity with exocrine pancreatic insufficiency, the densitogram rates were statistically significantly lower than in patients in the 1-st group.
Conclusions: The changes of bone tissue can be explained by the formation of trophological insufficiency as a result of exocrine pancreatic insufficiency. One of the symptoms of trophic failure is bone and mineral changes, in particular, the decrease of bone density.
PROSPECTS OF EUTHANASIA LEGAL REGULATION IN UKRAINE
Authors: Pavlenko Tetіana A. , Dunaieva Tetіana Ye. , Valuiska Marina Yu.
Published: January 2021

The aim of this article is to explore the ways of euthanasia regulation and to propose the most effective one.
Materials and methods: The authors of the article used the methods of analysis and synthesis, a comparative legal method. The scientific literature is evaluated and analyzed along with the experience of European countries, data of Ukrainian and international organizations and the results of scientific researches.
Conclusions: the understanding of euthanasia should be reviewed in terms of the possibility in exceptional cases of its executing for terminally ill person. This is an inherent human right. However, it is established that the right to dispose of his life belongs exclusively to the bearer of this right and it cannot be delegated.
LUNG NODULE 25 YEARS AFTER LOBECTOMY – RECURRENCE OF BRONCHIAL CARCINOID
Authors: Bełz Aleksandra , Rosiek Violetta , Głogowska- Szeląg Joanna , Stęplewska Katarzyna , Kos-Kudła Beata
Published: January 2021

Introduction: Bronchopulmonary (BP) carcinoids are low and intermediate grade tumors, seen in adults between fourth to sixth decade, where no clear association with tobacco smoking is established. Most often they are sporadic lesions (95%). Half of patients have no symptoms and the tumor is incidentally found on a chest x- ray. BP carcinoids have a good prognostic, however there is a risk of distant metastasis and the recurrences are frequent. Therefore a crucial role of vigilant follow- up, extending far beyond 5 years.
Case presentation: We report a case of 73 years old women, with history of recurrent pulmonary infections, and positive family history for lung cancer. Patient underwent left inferior lobectomy for BP carcinoid 25 years before and completed a 5 years long follow- up. On a thoracic computed tomography scan a nodule in the right lung was detected. Patient benefited from surgery and the pathological result was typical carcinoid with Ki67<1%. Follow- up CT scans showed stable images, with no signs of spread or recurrence.
Conclusions: Although there is a low risk of distant spread in such tumors, the recurrences are frequent. Moreover, patients may exhibit a higher risk of development of second tumors and there is a risk of metachronous tumors. The post-operative follow-up should be prolonged.
DYSPNOEA AS THE FIRST SYMPTOM OF COLON CANCER
Authors: Jakubiak Grzegorz K. , Ochab-Jakubiak Józefina , Król-Zybura Anna , Cieślar Grzegorz , Stanek Agata
Published: January 2021

Introduction: Colorectal cancer is one of the most frequently diagnosed cancer worldwide. Abdominal pain, alteration of chronic bowel habits, changes in bowel movements and involuntary weight loss belong to typical symptoms. It is important to diagnose the disease in early stage to improve effectiveness of treatment.
The aim: To present a case report of exertional dyspnoea in patient with newly diagnosed colorectal cancer without any symptoms and abnormalities in physical examination suggesting malignant process of digestive tract.
Case report: We present a 71-year-old male who has been admitted to the Department of Internal Medicine, Angiology and Physical Medicine under emergency care,
where was aimed at by general practitioner to diagnose exertional dyspnoea ongoing last few weeks, which appearing after two hundred meters walk on flat surface.
In the course of the diagnostic process, it turned out that the cause of dyspnoea was colorectal cancer.
Conclusions: This case report shows that initial symptoms of cancer may be nonspecific and it confirms how important it is for doctors to remain vigilant in the diagnostic process.
EPISIOTOMY INFECTIONS IN THE PUERPERIUM AND ANTIMICROBIAL
RESISTANCE OF RESPONSIBLE PATHOGENS IN UKRAINE
Authors: Salmanov Aidyn G. , Voitok Taras G. , Maidannyk Igor V. , Vdovychenko Serhiy Yu. , Chorna Olena О. , Marushchenko Yurii L. , Lugach Olga O.
Published: January 2021

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ABSTRACT
The aim: To obtain the first estimates of the current prevalence rate of episiotomy infections in the puerperium and antimicrobial resistance of responsible pathogens in Ukraine.
Materials and methods: We performed a retrospective multicenter cohort study was based on surveillance data. The study population consisted of all women who had a
vaginal delivery in 7 Regional Women’s Hospitals of Ukraine. Definitions of episiotomy infections were used from the Centers for Disease Control and Prevention’s National
Healthcare Safety Network (CDC/NHSN).
Results: Total 35.6% women after vaginal delivery had episiotomy done. The prevalence rate of episiotomy infections was 17.7%. The predominant pathogens were: Escherichia
coli (49.2%), Enterobacter spp. (11.1%), Streptococcus spp. (9.1%), Enterococcus faecalis (6.5%), Klebsiella spp. (8.1%), followed by Pseudomonas aeruginosa (4.7%), Staphylococcus
aureus (4.2%), Proteus spp.(2.9%) and Staphylococcus epidermidis (2.8%). The overall proportion of methicillin-resistance was observed in 17.3% of Staphylococcus aureus
(MRSA). Vancomycin resistance was observed in 6.8% of isolated enterococci. Carbapenem resistance was identified in 8% of P.aeruginosa isolates. Resistance to third-generation
cephalosporins was observed in 15.2% Klebsiella spp. and E.coli 16.4% isolates. The overall proportion of extended spectrum beta-lactamases (ESBL) production among
Enterobacteriaceae was 26.4%. The prevalence of ESBL production among E. coli isolates was significantly higher than in K. pneumoniae (31.4%, vs 12.5%).
Conclusions: Episiotomy infections in the puerperium are common in Ukraine and most of these infections caused by antibiotic-resistant bacteria. Optimizing the management
and empirical antimicrobial therapy may reduce the burden of episiotomy infections, but prevention is the key element.
KNOWLEDGE OF YOUNG ADULTS ABOUT NEURODEGENERATIVE DISEASES AND NEUROPROTECTIVE FOOD
Authors: Nowak Zuzanna , Barnabe Vivian Carbogno , Łabuz-Roszak Beata
Published: January 2021

The aim: To assess the knowledge of young adults about neurodegenerative diseases and neuroprotective food.
Material and methods: The study was conducted using an anonymous self-constructed questionnaire. 150 people aged 18 – 30 participated in the study, including 69% (n = 104) women and 31% (n = 46) men.
Results: Most of the respondents had sufficient or good knowledge of neurodegenerative diseases and neuroprotective nutrition. The obtained results did not depend on gender, place of residence, and age. However, knowledge was influenced by education (p < 0.05; better-educated respondents indicated more correct answers), and the occupation performed (p < 0.05; respondents performing medical professions gave correct answers more often).
Conclusions: It seems essential to introduce additional school classes in the field of neurodegenerative diseases and neuroprotective nutrition. Only modern nutritional education from an early age can help implement appropriate eating habits in the field of prevention of neurodegenerative diseases and their application in adulthood.
THE ASSOCIASON OF VITAMIN D RECEPTOR GENE (VDR) POLYMORPHISMS WITH HIGH BLOOD PRESSURE IN STROKE PATIENTS OF UKRAINIAN POPULATION
Authors: Obukhova Olha A. , Ataman Alexander V. , Zavadska Maryna M. , Piven Svetlana M. , Levchenko Zoia M.
Published: January 2021

The aim: To study the association of the polymorphisms VDR gene with high blood pressure in stroke patients in the Ukrainian population.
Materials and methods: Venous blood of 170 patients with atherothrombotic ischemic stroke (AIS) and 124 healthy individuals (control group) was used for genotyping. Four
polymorphisms (FokI, BsmI, ApaI, TaqI) of gene VDR were examined with PCR-RFLP methodology. Statistical analysis was performed by using SPSS-17.0 program.
Results: The correlation of genotypes of polymorphic variants of FokI, BsmI, ApaI and TaqI of the VDR gene with the development of ischemic atherothrombotic stroke in individuals with normal and high blood pressure was detected. Statistical analysis of the obtained data revealed that among carriers of genotypes F/F, b/b, a/a, a/A, and T/T patients with AI have statistically significantly higher incidence of hypertension than patients in the control group.
Conclusions: It was found that persons with genotypes F/F, b/b, a/a, a/A, and T/T showed a statistically significant relationship between hypertension and the development of IAS. The application of logistic regression has made it possible to establish that the risk of IAS in people with normal blood pressure and genotype F/f is 3.2 times higher than in normotensive homozygotes for the F-allele.
BAD HABITS AND THEIR IMPACT ON STUDENTS’ HEALTH
Authors: Griban Grygoriy P. , Myroshnychenko Mykhailo S. , Tkachenko Pavlo P. , Yavorska Tetiana Ye. , Kolesnyk Nataliia Ye. , Novitska Inesa V. , Verbovskyi Igor А.
Published: January 2021

The aim: Is to investigate the bad habits of the students of higher education institutions and their impact on health.
Materials and methods: The research of the students’ bad habits was conducted at Polissia National University and Zhytomyr Ivan Franko State University in 2014-2019. 647 students of different specialties between the ages of 17 and 23 were interviewed. The research methods included theoretical methods (the analysis and generalization of literary sources, the evaluation of the quality of students’ performance in classes, the study and analysis of the medical records of students); empirical methods (pedagogical observations, questionnaires, surveys); the methods of mathematical statistics.
Results: The study found that 32.4 % of male students and 14.9 % of female students smoke. It was defined that male students of the special education department smoke the most – 37.7 %; 32.5 % and 27.1 % of the male students of the main and sports departments smoke respectively. Among female students, 18.4 % of the students of the sports department, 14.6 % – of the main department and 13.4 % – of the special department smoke. The study determined that 2.7 % of both male and female students of the first year of study drink alcohol almost every day, 3.7 % – 2-3 times a week, 18.2 % – once a week, 66.0 % – only on holidays. Besides, the research indicated that some students use drugs. It was found that the students know that smoking, alcohol, and drugs are harmful but cannot or do not want to get rid of these bad habits.
Conclusions: The study established that the environment of students is unfavorable for the activation of the healthy lifestyle components; it contributes to the spread of bad habits, the consequences of which students do not realize fully. Many students do not have a need to take care of their own health.
THE EFFECT OF ATORVASTATINUM IN THE TREATMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS
Authors: Shevchuk Sergii V. , Seheda Yuliia S. , Kuvikova Inna P. , Shevchuk Olena V. , Galiutina Olena Y.
Published: January 2021

The aim: Was to evaluate the effect of 6-month pathogenetic treatment in combination with atorvastatinum on the endothelium function, lipid and adipokine levels, paroxonase activity and activity of inflammatory process in RA patients.
Materials and methods: The study included 55 patients with RA, dividing into two groups depending on the intended therapy. The first group included 33 patients with “traditional” treatment by methotrexate, glucocorticoids, and non-steroid anti-inflammatory drugs. The second group included 22 patients with “traditional” treatment and additionally prescribed of atorvastatinum 20 mg/day. The lipid profile, leptin, adipokine, paroxonase activity. C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-α) levels, FMDBA and IMT of carotid artery were determined in all participants of the study. Control parameters were recorded before the start, after 1 and 6 months of treatment.
Results: The FMDBA has increased by 32% in the second group, compared by only 10.9% in the first group. The dynamics of IMT in the first group was also twice lower than in group with the additional use of atorvastatinum. The leptin levels in the second group significantly decreased by 27% and adiponectin levels increased by 12.8%, than in the first group – by 12.8% and by 7% respectively. The appointment of statins over 6 months resulted in DAS28, TNF-α, ESR and CRP reduction by 15%, 31%, 25% and 21.5% respectively. In the first group the dynamics of indicate rates ranged from 7.8% to 22.5%, and was significantly lower than in the second group.
Conclusions: As a result of the study, it was found that the appointment of atorvastatinum 20 mg/day during 6 months not only reduces dyslipidemia, but also significantly reduces the inflammatory process and adipokine dysregulation, normalizes serum paraoxonase activity and improves the endothelium function.