bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the Possible Relationship between the Curvature and
Horizontal Course of the Inferior Alveolar Canal
Authors: Koca Cansu G. , Çiçek M. Fatih , Sadry Sanaz , Yenidünya Ozan , Kaplan Fatma Akkoca , Erdil Aras
Published: February 2023

Objectives:

The position of the inferior alveolar canal (IAC) and its course in the mandible
is crucial to prevent complications in oral surgical procedures. Therefore, the present study aims to
predict the course of IAC using landmarks specific to the mandible and to correlate with cone-beam
computed tomography images.

Methods:

On the included panoramic radiographs (n=529), the closest point of the IAC to the inferior
border of the mandible (Q) was determined, and the distances of this point to the mental (Mef) and
mandibular foramen (Maf) were measured in millimeters. To determine the buccolingual course of the
IAC on CBCT images (n=529), the distances from the center of the canal to the buccal and lingual
cortices and between the cortices were measured at the level of the root apices of the first and second
premolars and molars. Also, the positions of the Mef to adjacent premolars and molars were classified.

Results:

The most common position of mental foramen was Type-3 (37.1%). On the coronal plane, it
was also observed that as the Q point approaches the Mef, the IAC is located in the mandible's center
at the second premolar level (p=0.008) and moves away from the midline at the level of the first molar
(p=0.007).

Conclusions:

Based on the results, a correlation was observed between the horizontal course of the IAC
and its proximity to the inferior border of the mandible. Therefore, the curvature of the IAC and its
proximity to the mental foramen should be considered in oral surgeries.
Review on Computer Aided Breast Cancer Detection and Diagnosis using
Machine Learning Methods on Mammogram Image
Authors: Kuttan Girija Ottathenggu , Elayidom Mannathazhathu Sudheep
Published: February 2023

Machine Learning (ML) plays an essential part in the research area of medical image processing.
The advantages of ML techniques lead to more intelligent, accurate, and automatic computeraided
detection (CAD) systems with improved learning capability. In recent years, deep learning-based
ML approaches developed to improve the diagnostic capabilities of CAD systems. This study reviews
image enhancement, ML and DL methods for breast cancer detection and diagnosis using mammogram
images and provides an overview of these methods. The analysis of different ways of ML and
DL shows that the usages of traditional ML approaches are limited. However, DL techniques have an
excellent future for implementing medical image analysis and improving the ability to exist CAD systems.
Despite the significant advancements in deep learning methods for analyzing medical images to
detect breast cancer, challenges still exist regarding data quality, computational cost, and prediction
accuracy.
Multisystem Sarcoidosis Combined with Sjögren's Syndrome: A Case
Report and Literature Review
Authors: Li Xiaoran , Wu Jing , Ruan Guangan , Chen Yu-Chen
Published: February 2023

Background:

Sarcoidosis is a systemic non-caseous necrotizing granulomatous disease with
unknown etiology. It can involve multiple organs throughout the body, most commonly affecting lungs
and/or bilateral hilar lymph nodes. Sjögren's syndrome is a multi-system autoimmune disease. The
main clinical symptoms include dry mouth and dry eyes. The combination of the two diseases with the
involvement of multiple systems is very rare, and the final diagnosis is mainly based on the comprehensive
judgment of clinical history, imaging manifestations and pathological examination.

Case presentation:

We report a case of multiple sarcoidosis (lung, hilar, mediastinal, inguinal, liver,
and spleen) with Sjögren syndrome. The patient had a dry mouth, dry eyes, and bilateral parotid gland
enlargement. The first computed tomography (CT) scan of the chest and abdomen showed multiple
nodules in the lungs, multiple enlarged lymph nodes, and low-density shadows in the liver and spleen.
After a one-year interval, the re-examination showed that the lung lesions increased with bead-like
changes, and the lymph nodes shrunk. Through pathological puncture and comprehensive judgment,
considering the coexistence of the two diseases, the patient improved after hormone therapy and was
finally diagnosed.

Conclusion:

Multisystem sarcoidosis combined with Sjögren's syndrome has rarely been reported in
the literature. This case has multiple imaging examinations, pathological data and a follow-up review
after treatment. The dynamic changes in different periods will help us to better understand the situation
of sarcoidosis and explore the connection between the two diseases so as to reduce misdiagnosis.
Iron Chelation and Antioxidant Properties of Withania somnifera
(Ashwagandha) Restore Fertility in Men and Women
Authors: Joshi Ruchira , Yadav Pratik , Bagwe-Parab Siddhi , Tuli Hardeep Singh , Buttar Harpal Singh , Kaur Ginpreet
Published: February 2023

Withania somnifera (Ashwagandha) is one of the most renowned and revered medicinal
plants in the Indian Ayurvedic system of medicine. Ashwagandha Rasayanas (tonics), capsules, tablets,
and powdered herbs (churna) have been used for curing a wide variety of ailments, including
reproductive problems, and for improving fertility in men and women as well as erectile dysfunction
(ED) in men. Iron accumulation in reproductive organs is caused by excessive dietary intake of iron,
dysregulation of iron transporters, chronic blood transfusions, and hemochromatosis. Iron overload
produces oxidative stress and causes atrophy of ovaries and testes and hypogonadism, which leads to
infertility in men and women. Emerging evidence from preclinical and clinical studies suggests that
excessive iron-induced infertility results from dysfunction of the hypothalamic-pituitary-gonadal axis
and consequently perturbs the secretion of sex hormones (GnRH, FSH, LH, estrogen, progesterone,
and testosterone). The focus of this review is to summarize the pathophysiology of iron-overload
toxicity of reproductive organs and the reversal of male/female infertility and libido with Ashwagandha.
The bioactive ingredients of Ashwagandha appear to restore iron–overload infertility by acting
on iron chelation and capturing iron free radicals (Fe+++) produced by the Fenton reaction. Many synthetic
drugs have been tried for treating iron overload infertility, but the outcome has been inconsistent.
Considering the high cost of these drugs, Ashwagandha may be a safer and more costeffective
phytomedicine to cure iron-overload infertility and enhance libido in humans. Collectively,
the iron chelation and antioxidant effects of Ashwagandha seem to reverse iron-overload infertility in
men and women by improving testicular and ovarian functions.
Design of Solid-contact Ion-selective Electrode with Multiwall-carbon
Nanotubes for Assay of Sulfacetamide in Rabbit Aqueous Humour
Authors: Hassan Said A. , Mahmoud Amr M. , Kamel Mona A. , Abbas Samah S. , Michael Adel M.
Published: February 2023

Background:

Inclusion of multiwall-carbon nanotubes (MWCNTs) as ion-to-electron transducers
within the ionophore-doped PVC membrane has a great impact on the stability and robustness of
the produced sensor performance compared to conventional liquid-based ISEs.

Objective:

Solid-contact ion selective electrodes (SC-ISEs) were fabricated and optimized for the assay of sulfacetamide sodium in both ophthalmic eye drops and in rabbit aqueous humor.

Methods:

2-hydroxypropyl-β-cyclodextrin (2HP-β-CD) was selected as an ionophore to dope the ionselective
membrane to enhance its selectivity towards sulfacetamide. The performance of multiwall-CNTs
as ion-to-electron transducer was evaluated by comparing MWCNT-based SC-ISE with control sensor
which does not include the MWCNTs. The electrochemical performance characteristics of the proposed
sensors were assessed in accordance with the IUPAC recommendations. A green profile assessment of the
proposed method was performed using Eco-Scale and AGREES metrics.

Results:

Inclusion of MWCNT into the sensing membrane improved the performance of the developed
sensor. The linearity range was (2.5 x 10-4 M - 1.0 x 10-2 M) for both sensors and the LOD was estimated
to be 5.6 x 10-5 M for GCE/ISM(CNT) and 1.5x 10-4 M for control sensor GCE/ISM. The results of green
assessment for both the developed and the official method showed an excellent greenness of the proposed
method.

Conclusion:

The proposed sensor can be applied successfully for the determination of sulfacetamide in eye drops and rabbit aqueous humour.
Neuroprotective Effect of Levetiracetam in Combination with Berberine on Scopolamine Induced-Cognitive Impairment in Mice: A Behavioral and Biochemical Approach
Authors: Singh Anuradha , Dhaneshwar Suneela Sunil , Mazumder Avijit , Kumar Swatantra , Saxena Shailendra Kumar
Published: February 2023

Background:

Presently, only four drugs have been approved by FDA for Alzheimer’s disease (AD). A drug repurposing approach can be fruitful in searching for promising candidates for AD.

Objective:

The objective of the work was to evaluate the neuroprotective effect of levetiracetam (LEV) in combination with berberine (BER) in scopolamine-induced cognitive impairment in mice by applying a drug repositioning approach owing to their antioxidant potential.

Methods:

Cognitive impairment was induced in mice by scopolamine. Morris water maze, elevated plus maze, and Y-maze were used to evaluate behavioral parameters. Assays for acetylcholinesterase (AChE), reduced glutathione (GSH), malondialdehyde (MDA), catalase, nitrite, TNF-α, and brain histopathology were performed.

Results:

The transfer latency time and percentage of spontaneous alternation were significantly reduced and significant alterations in AChE and MDA levels, GSH concentration, and improvement in nitrite and catalase levels were also evidenced after the treatment of mice with a combination of LEV and BER in comparison to independent drugs, standard and disease control groups. The antioxidant defense was also improved and TNF-α levels were significantly reduced by a combination of LEV and BER. Improvement in neuronal damage by restoration of the cytoarchitecture of the brain was also seen in the histopathological study of the brain of treatment groups.

Conclusion:

The present study has demonstrated that the combination of LEV and BER has significantly improved cognition in mice by lipid peroxidation inhibition, augmentation of endogenous antioxidant enzymes, the decline in TNF- α levels, and AChE activity in the brain when compared to individual drugs, standard and disease control owing to their strong antioxidant and anti-inflammatory potentials.
Impact of COVID-19 on Anxiety and Depression - Biopsychosocial
Factors
Authors: Bertollo Amanda Gollo , Leite Galvan Agatha Carina , Dama Mingoti Maiqueli Eduarda , Dallagnol Claudia , Ignácio Zuleide Maria
Published: February 2023

Anxiety and depression are prevalent mental disorders around the world. The etiology of
both diseases is multifactorial, involving biological and psychological issues. The COVID-19 pandemic
settled in 2020 and culminated in several changes in the routine of individuals around the world, affecting
mental health. People infected with COVID-19 are at greater risk of developing anxiety and
depression, and individuals previously affected by these disorders have worsened the condition. In addition,
individuals diagnosed with anxiety or depression before being affected by COVID-19 developed
the severe illness at higher rates than individuals without mental disorders. This harmful cycle
involves several mechanisms, including systemic hyper-inflammation and neuroinflammation. Furthermore,
the context of the pandemic and some previous psychosocial factors can aggravate or trigger
anxiety and depression. Disorders are also risks for a more severe picture of COVID-19. This review
discusses research on a scientific basis, which brings evidence on biopsychosocial factors from
COVID-19 and the context of the pandemic involved in anxiety and depression disorders.
Restoration of Altered Oncogenic and Tumor Suppressor microRNA
Expression in Breast Cancer and Colorectal Cancer Cell using Epicatechin
Authors: Kiran Sheetal , Patra Abhilipsa , Verma Poonam , Purkait Suvendu , Chhabra Gaurav , Guttula Praveen Kumar , Ghosh Amit
Published: February 2023

Background:

MicroRNAs (miRNA) are small non-coding RNAs that regulate the function of mRNA post-transcriptionally in a tissue-specific manner. miRNA expressions are heavily dysregulated in human cancer cells through various mechanisms, including epigenetic changes, karyotype abnormalities, and miRNA biogenesis defects. miRNAs may act as either oncogenes or tumor suppressors under different conditions. Epicatechin is a natural compound found in green tea which possesses antioxidant and antitumor properties.

Objective:

The objective of this study is to investigate the effect of epicatechin treatment on the expression level of several oncogenic and tumor suppressor miRNAs in breast and colorectal cancer cell lines (MCF7 and HT-29) and identify its mechanism of action.

Methods:

The MCF-7 and HT29 cells were treated with epicatechin for 24 hours and untreated cells were considered control cultures. miRNA was isolated and qRT-PCR was used to measure the expression profile changes of different oncogenic and tumor suppressor miRNAs. Furthermore, the mRNA expression profile was also screened at different concentrations of epicatechin.

Results:

Our results showed several-fold changes in miRNAs expression level, which is cell line specific. Also, epicatechin at different concentrations induces biphasic changes in mRNA expression levels in both cell lines.

Conclusion:

Our findings first time demonstrated that epicatechin can reverse the expression of these miRNAs and may trigger the cytostatic effect at a lower concentration.
Greener Approaches Towards 1,4–Benzothiazine Synthesis: Recent Updates
and Outlook
Authors: Bhattacharya Suchandra , Basu Basudeb
Published: February 2023

Heterocyclic moieties are ubiquitous in nature and the exploration of heterocyclic chemistry
goes centuries back, which have coalesced into the invention of greener methodologies towards
the synthesis of heterocycles of potential uses. Benzothiazine is an important class of heterocyclic
molecule, in which a benzene ring is fused with a six–member N, S containing ring.
Amongst the three possible isomers, 1,4–benzothiazines show a wide spectrum of pharmaceutical
and biological activities like anti–inflammatory, anti–rheumatic, antihypertensive, andantipathogenic
roles. In search of greener protocols,metal–free catalysts, and environmentally benign reaction
conditions, a lot have been unboxed to date, and many other dimensions remain yet to be deciphered.
This minireview is an attempt to classify various sustainable protocols for the synthesis
of 1,4–benzothiazine scaffolds over the last decade based on the reacting components and pathways,
along with the consideration of plausible mechanistic insights and critical analysis.
Intelligent Prediction of Photovoltaic Power Generation Considering
Uncertainty Measurement
Authors: Fan Guo-Feng , Ge Qing-Yi , Ren Si-Jie , Hu Shao-Xiang , Hong Wei-Chiang
Published: February 2023

Background:

As a renewable energy, solar energy has the advantages of being nonpolluting,
clean, and renewable. With the variability of solar radiation, the complexity of meteorological
factors, and other uncertain changes, how to measure its comprehensive uncertainty is very important.

Objective:

The inherent regularity of the uncertainty behavior of photovoltaic power generation is revealed
by the change process of photovoltaic power generation.

Methods:

Using the empirical wavelet transform (EWT), the uncertainty measurement was studied
from the perspective of social physics, and an optimized intelligent prediction model (PSOBOALSTM)
was proposed based on the uncertainty.

Results:

The intelligent prediction model (PSOBOA-LSTM) has a better prediction effect and higher
accuracy than other models, and reveals the internal mechanism of the photovoltaic power generation
system from the perspective of physics and sociology.

Conclusion:

Using the PSOBOA-LSTM model can better facilitate the power dispatching department
to reasonably arrange conventional power generation, coordinate operations and make maintenance
arrangements based on the predicted photovoltaic power generation, and solve problems arising from
the connection between grid dispatching and photovoltaic power generation forecasting.
Potential Oncotherapeutic Effects of Nutraceuticals against Hepatocellular
Carcinoma: Recent Advancements
Authors: Das Arghadip , Das Supravat , Bhattacharya Sanchari , Sur Debjeet , Bose Samrat , Mukherjee Tilottama
Published: February 2023

Background:

Worldwide, Hepatocellular carcinoma (HCC) is a frequently diagnosed
cancer, having significant variations in its epidemiology. It ranks as the sixth prevailing neoplasm
and is considered the third leading cause of mortality due to cancer. It accounts for 90% of primary
liver cancers. Till date, an effective prevention or treatment is absent except for liver resection,
chemotherapy and a frequently applied drug -sorafenib. Recently, various plant products and
nutraceuticals are found to be effective in the treatment of HCC. ‘Nutraceuticals’ is a term that
brings into light the two giants of health sciences - nutrient and pharmaceutical. Nutraceuticals
provide medical or health benefits and include prevention or treatment of a disease. These are
generally ‘functional foods’, which are whole, or ‘fortified, enriched and enhanced’ in nutritional
value to satisfy the required amount of essential nutrients and to confer health benefits.

Objective:

This study is based on the recent advancements achieved in the field of HCC treatment
using a variety of emerging nutraceuticals that are effective, solely, or act as an adjuvant in its
treatment. Nutraceuticals such as standardized extracts of ginger, fucoidan, curcumin, proanthocyanidins,
epigallocatechin gallate, apigenin and other nutraceuticals are being studied extensively
for their efficacy against HCC along with their proposed mechanism of action or potential
targets for the treatment or prevention of HCC.
A clinical study on the efficacy of Isabgol as a Pathya along with Yogabhyas and Yastimadhu Siddha Taila Matra Basti in the management of Parikartika w.s.r. to Acute Fissure-in-Ano
Authors: Arif Khan Goran  , Pramod Kumar Mishra  , Mahesh Kumar  , Neha Bhanot
Published: February 2023

Swasthavritta Palana is the primary prevention mentioned in classics. By the practice of which an individual always lives with healthiness, a physician should instigate for such practice as because good health is the most desirable objects of human beings. This can be achieved by means of preventing diseases, preserving, and promoting health. The Aahar-Vihar which is beneficial and nutritional to the body and also give the happiness to the mind is known as Pathya and opposite to that is known as Apathya. Acharaya Charaka mentions that the people living in Jangala Pradesha are dry and they have dry food that vitiates Vata and produces Vibanda or constipation. Acharaya Susruta describes as Pitta & Vata Dosha predominance in Parikartika. Hence the proper and effective therapy is required for the treatment of anal fissure which is simple, safe and effective, without any complication, avoidance of incontinence of stool and recurrence at end of therapy. Still there is need of evaluation of certain drugs clinically on various scientific parameters which could be safe, effective, cheap & radially available in the management of Parikartika.
Prospective study of Medhya effect of Guduchi Rasayana in different Dehaprakruti
Authors: Parag Salvi  , Amit S. Mujumdar  , Sudarshan K. Hande  , Vishal N. Kulkarni  , Santosh G. Chavhan  , Kavita S. Turambekar
Published: February 2023

Ayurveda has explained the concept of Rasayana (Rejuvenating Therapy), a classical medication mainly aiming at protection of the individual's health and secondarily at pacification of disease. Different types of Rasayanas are described in Samhitas for specific purposes. Improvement of Medha i.e., intelligence is one of the benefits of consumption of Rasayana. Medhya Rasayana is one of the types of Rasayana which majorly deals with enhancement of Medha i.e., intelligence along with other benefits of Rasayana. The Medhya effect of Guduchi Rasayana is studied with the help of Intelligent Quotient i.e., IQ. The proper assessment of IQ is done with the help of Catell & Catell Intelligence scale. The normal functioning of Medha mainly depends on Pitta Dosha. Pitta in its normal state is Katu Rasatmak (Pungent taste) and related with the Satva Guna of Manas. Guduchi, being Katu-Tikta Rasatmak and Madhura Vipaka Dravya, purifies the Pitta Dosha and enhances Satva Guna by removing Tamas. Tikta Rasa has been described as Medhya by Vagbhatacharya. This study attempted to analyze any changes in IQ due to consumption of Guduchi Rasayana in different Dehaprakruti.
Effect of Shampakadi Niruha Basti in the management of Katigraha w.s.r. to Lumbar Disc Herniation - A Pilot Clinical Study
Authors: Shubham Borkar
Published: February 2023

Lumbar disc herniation (LDH) is the most common lumbar spinal disorder that produces low back pain and/or leg pain. A herniated disc is a displacement of disc material (nucleus pulposus or annulus fibrosis) beyond the intervertebral disc space. LDH may be correlated with Katigraha in Ayurveda on the basis of clinical features of the disease where Vatadosha with or without Aamadosha settles in Katipradesh (lumbar region). and cause pain and stiffness. In the present study 6 patients of lumbar disc herniation were advised the treatment modalities like Shampakadi Niruha Basti along with Rasnaerandadi Kashayam and Trayodasang Guggulu orally for 16 days which was found very effective in relieving the sign and symptoms of LDH.
Pharmaceutical Study of Kayyonyadi Taila
Authors: V K Roshni , Ch Sridurga
Published: February 2023

Background: Sneha Kalpana is a unique preparation of oleaginous medicine which is included under Bhaishajya Kalpana. It is again of two types Ghrita and Taila Kalpana. Kayyonyadi Taila is one such formulation which is mentioned in Chikitsa Manjari, Sahasrayogam for the management of Palithya. Kayyonnyadi Taila contains Bhringaraja, Guduchi, Amalaki, Goksheera, Tila Taila, Yastimadhu and Neelanjana. Aim: To prepare Kayyonyadi Taila, pharmaceutical study of Kayyonyadi Taila. Methods: Kayyonyadi Taila was prepared according to the general method of preparation of Taila. The pharmaceutical procedures which were adopted in this study include Swarasa Nirmana, Shodhana, Churna Nirmana, preparation of Kalka and preparation of Kayyonyadi Taila. Results: 10L of Taila was obtained as the final product with a loss of 500ml. Conclusion: The main cause of Palithya/greying of hair is due to the vitiated Pitta Dosha. Colour of hair is mainly due to melanocytes present in hair cells. Contemporary medicine does not offer any satisfactory treatment for Canities. Kayyonyadi Taila is beneficial in Palithya and the pharmaceutical study results was considered as a standard for the preparation of Taila.
Web-Based Conversations Regarding Fathers Before and During the COVID-19 Pandemic: Qualitative Content Analysis
Authors: Bouchacourt Lindsay , Henson-García Mike , Sussman Kristen Leah , Mandell Dorothy , Wilcox Gary , Mackert Michael
Published: February 2023

Background

Studies of new and expecting parents largely focus on the mother, leaving a gap in knowledge about fathers.

Objective

This study aimed to understand web-based conversations regarding new and expecting fathers on social media and to explore whether the COVID-19 pandemic has changed the web-based conversation.

Methods

A social media analysis was conducted. Brandwatch (Cision) captured social posts related to new and expecting fathers between February 1, 2019, and February 12, 2021. Overall, 2 periods were studied: 1 year before and 1 year during the pandemic. SAS Text Miner analyzed the data and produced 47% (9/19) of the topics in the first period and 53% (10/19) of the topics in the second period. The 19 topics were organized into 6 broad themes.

Results

Overall, 26% (5/19) of the topics obtained during each period were the same, showing consistency in conversation. In total, 6 broad themes were created: fatherhood thoughts, fatherhood celebrations, advice seeking, fatherhood announcements, external parties targeting fathers, and miscellaneous.

Conclusions

Fathers use social media to make announcements, celebrate fatherhood, seek advice, and interact with other fathers. Others used social media to advertise baby products and promote baby-related resources for fathers. Overall, the arrival of the COVID-19 pandemic appeared to have little impact on the excitement and resiliency of new fathers as they transition to parenthood. Altogether, these findings provide insight and guidance on the ways in which public health professionals can rapidly gather information about special populations—such as new and expecting fathers via the web—to monitor their beliefs, attitudes, emotional reactions, and unique lived experiences in context (ie, throughout a global pandemic).
What do e-health services in Spain offer and what are the demands of users? A national survey (Preprint)
Authors: Cernadas Ramos Andrés , Fernández Da Silva Ángela , Barral Buceta Bran , Bouzas-Lorenzo Ramón
Published: February 2023

BACKGROUND

The accelerated development of ICTs has made healthcare one of the pioneering fields in the incorporation of these tools. New technologies have been applied; the existing ones have been sophisticated and improved, and the concept of e-Health has expanded These advances and expansion of e-Health, however, do not seem to have served to adapt the supply of services to users’ demand; rather, supply seems to be governed by other variables.

OBJECTIVE

The main objective of this work is to review the existing differences between user demands and the supply of e-Health services in Spain and their causes. The aim is to provide information on the level of use of the services, the causes of the variation in demand for these services, which can be useful in correcting existing differences and adapting them to the needs of users.

METHODS

A Survey of Use and Attitudes towards e-Health in Spain was applied by phone to a sample of 1,695 people of legal age, taking into account sociodemographic profile characteristics (sex, age, habitat, educational level). The confidence level was of 95%, and a margin of error of ±2.45 for the whole sample.

RESULTS

The results obtained show that the online doctor's appointment service is the most used by users: 72.48% have used it at some time and 21.28% say they use it regularly, while other services show significantly lower percentages of use: "managing health cards" (28.04%), "consulting medical history" (20.37%), "managing test results" (20.22%), "communicating with health professionals" (17.80%) and "requesting a change of doctor" (13.76%). Despite this low usage, a large majority of respondents (80%) attach great importance to all the services offered. 16.52% of the users surveyed were willing to make new service requests to the regional websites, with 9.33% of them highlighting services such as "the availability of a complaints and claims mailbox", "the possibility of consulting medical records" and "the availability of more detailed information on medical centres (location, medical directory, waiting lists, etc.)". Other outstanding requests (8.00%) were to simplify the procedures for using certain existing services.

CONCLUSIONS

The data from the survey show that eHealth services are widely known and highly valued by users, but not all are used with the same frequency or intensity. It appears that users find it difficult to suggest new services that might be useful to them in terms of demand for new services that do not currently exist. It would be useful to use qualitative studies to gain a deeper understanding of their currently unmet needs and the possibilities of e-Health. The lack of access to and use of these services and the unmet needs particularly affect the less able, as they have the greatest difficulty in meeting their needs through alternative means.
Visual Analytics of Multidimensional Oral Health Surveys: Data Mining Study (Preprint)
Authors: Xu Ting , Ma Yuming , Pan Tianya , Chen Yifei , Liu Yuhua , Zhu Fudong , Zhou Zhiguang , Chen Qianming
Published: February 2023

BACKGROUND

Oral health surveys largely facilitate the prevention and treatment of oral diseases as well as the awareness of population health status. As oral health is always surveyed from a variety of perspectives, it is a difficult and complicated task to gain insights from multidimensional oral health surveys.

OBJECTIVE

We aimed to develop a visualization framework for the visual analytics and deep mining of multidimensional oral health surveys.

METHODS

First, diseases and groups were embedded into data portraits based on their multidimensional attributes. Subsequently, group classification and correlation pattern extraction were conducted to explore the correlation features among diseases, behaviors, symptoms, and cognitions. On the basis of the feature mining of diseases, groups, behaviors, and their attributes, a knowledge graph was constructed to reveal semantic information, integrate the graph query function, and describe the features of intrigue to users.

RESULTS

A visualization framework was implemented for the exploration of multidimensional oral health surveys. A series of user-friendly interactions were integrated to propose a visual analysis system that can help users further achieve the regulations of oral health conditions.

CONCLUSIONS

A visualization framework is provided in this paper with a set of meaningful user interactions integrated, enabling users to intuitively understand the oral health situation and conduct in-depth data exploration and analysis. Case studies based on real-world data sets demonstrate the effectiveness of our system in the exploration of oral diseases.
Supporting Collaboration in Rehabilitation Trajectories With Information and Communication Technologies: Scoping Review (Preprint)
Authors: Gåsvær Jo Inge , Jepsen Randi , Heldal Ilona , Sudmann Tobba
Published: February 2023

BACKGROUND

Despite a surge in health information and communication technology (ICT), there is little evidence of lowered cost or increased quality of care. ICT may support patients, health care providers, and other stakeholders through complex rehabilitation trajectories by offering digital platforms for collaboration, shared decision-making, and safe storage of data. Yet, the questions on how ICT can become a useful tool and how the complex intersection between producers and users of ICT should be solved are challenging.

OBJECTIVE

This study aims to review the literature on how ICTs are used to foster collaboration among the patient, the provider, and other stakeholders.

METHODS

This scoping review follows the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines. Studies were identified by searching MEDLINE (OVID), Embase (OVID), CINAHL (EBSCOhost), AMED (EBSCOhost), and Scopus. Unpublished studies were extracted from OAIster, Bielefeld Academic Search Engine, ProQuest Dissertations and Theses, NARIC, and Google Scholar. Eligible papers addressed or described a remote dialogue between stakeholders using ICT to address goals and means, provide decision support, or evaluate certain treatment modalities within a rehabilitation context. Due to the rapid development of ICTs, searches included studies published in the period of 2018-2022.

RESULTS

In total, 3206 papers (excluding duplicates) were screened. Three papers met all inclusion criteria. The papers varied in design, key findings, and key challenges. These 3 studies reported outcomes such as improvements in activity performance, participation, frequency of leaving the house, improved self-efficacy, change in patients’ perspective on possibilities, and change in professionals’ understanding of patients’ priorities. However, a misfit between the participants’ needs and the technology offered, complexity and lack of availability of the technology, difficulties with implementation and uptake, and lack of flexibility in setup and maintenance reduced the value of ICT for those involved in the studies. The low number of included papers is probably due to the complexity of remote collaboration with ICT.

CONCLUSIONS

ICT has the potential to facilitate communication among stakeholders in the complex and collaborative context of rehabilitation trajectories. This scoping review indicates that there is a paucity of research considering remote ICT-supported collaboration in health care and rehabilitation trajectories. Furthermore, current ICT builds on eHealth literacy, which may differ among stakeholders, and the lack of sufficient eHealth literacy and ICT knowledge creates barriers for access to health care and rehabilitation. Lastly, the aim and results of this review are probably most relevant in high-income countries.
A STUDY ON CLINICAL PROFILE AND OUTCOME OF RODENTICIDE POISONING IN SOUTH INDIA: A CROSS-SECTIONAL STUDY
Authors: MURUGESAN MALARVIZHI , NATARAJAN RADHAKRISHNAN , PANDIAN PRASANNA DEVI , SHANMUGAM JEEVITHAN
Published: February 2023

Objectives: The objectives of the study were to study the sociodemographic profile, clinical features, and clinical outcome of patients admitted with rat killer poison in a tertiary care hospital in South India.
Methods: A cross-sectional study was conducted among those who have been admitted with rodenticide poisoning in a tertiary care center in South India. Prior Institutional Ethical committee Permission and written informed consent were obtained. Data on sociodemographic profile were elicited. The clinical course of all those who were enrolled in the study was closely followed and monitored. All the necessary blood parameters were done on every alternate day after the admission blood investigations. The data were entered into Microsoft excel and were analyzed using PSPP software. The difference in mean blood parameters between survivors and non survivors was compared.
Results: The consumption of rodenticide poisoning was higher among females (59%). Majority (58%) were married. Vomiting was present in nearly two-third of the study population and abdominal pain in 21%. Dose ingested and time of reporting to hospital were high among non-survivors. Mean bilirubin, serum glutamic-oxaloacetic transaminase, serum glutamic pyruvic transaminase, and International normalized ratio were higher among non-survivors compared to survivors at all the days measured.
Conclusions: Monitoring of liver parameters plays a key role in assessing the prognosis of the patient and also in treating them.
STUDY OF BACTERIAL PATHOGENS CAUSING URINARY TRACT INFECTION AND ANTIBIOGRAM PATTERN IN SYMPTOMATIC ADULTS
Authors: M RAVISH KUMAR , N SHRUTHI
Published: February 2023

Objectives: Urinary tract infections (UTIs) are most common infection seen in community and hospital. It is important to know the causative agent and antibiotic susceptibility pattern to administer specific treatment and prevent drug resistance. Hence, the present study was conducted to know the most common etiological agent and antibiogram of symptomatic UTIs.
Methods: The study was conducted at a tertiary care hospital. All the adult patients presented with symptoms of UTI were involved. As per the standard guidelines, clean catch mid-stream urine sample was collected and inoculated on MacConkey’s agar and blood agar by standard loop technique. The isolates with significant bacteriuria were subjected for Kirby-Bauers’ disk diffusion antibiotic susceptibility testing.
Results: One thousand two hundred and fifty symptomatic patients were screened for UTI. A total of 358 organisms were isolated in culture with significant bacteriuria. Among 358, Escherichia coli was commonest organism with 267 (74.5%), followed by Klebsiella species accounting for 52 isolates (14.5%) and Citrobacter species 25 (7.0%), and Pseudomonas aeruginosa 14 (4%). Higher degree of sensitivity was seen with imipenem (90%), amikacin (80%), and gentamycin (78%) followed by nitrofurantoin (75%) for E. coli. Lower degree of sensitivity was noted for norfloxacin (50%), ceftriaxone (62%), cotrimoxazole (56%), and pipericillin-tazobactum (60%). Klebsiella was sensitive to amikacin (74%) and imipenem (80%).
Conclusion: In the present study, E. coli was the most common organism causing UTI. Nitrofurantoin can be started as empirical treatment for lower UTI. Gentamycin was found to be equally effective as amikacin so that it can be used instead of amikacin to decrease the selective pressure on amikacin.
ROLE OF FNAC IN BONE LESIONS, A CYTOLOGICAL AND HISTOLOGICAL CORRELATION IN A TERTIARY CARE CENTER IN CENTRAL INDIA
Authors: SINGH PUJA , JOHER MUNIRA , MERAVI JYOTI , TRIPATHI SONALI
Published: February 2023

Objectives: FNAC plays a pivotal role in any lesion for the ease of diagnosing and treatment of an ailment. The role of FNAC in bone lesions has not been studied in great vastness but it can definitely ease the time taken for diagnosing on histopathology. The aim of the study was to study the sensitivity, specificity, positive predictive value, and negative predictive value of FNAC in bone lesions, comparison of cytological findings to histopathological findings and to identify the accuracy of FNAC in bone lesions.
Methods: The study was retrospective and observational study. All the FNAC samples were studied and correlated with the histopathology findings where available.
Results: A total of 92 cases were studied. The accuracy of the study stands at 81.3% along with the sensitivity of 87.5% and specificity of 75% with a positive predictive value of 77.8%. Non-neoplastic lesions were 18, followed by primary benign bone tumors 29, Primary malignant bone tumors 28, secondary tumors of bone 6, and unsatisfactory smears 11 cases were identified.
Conclusion: FNAC plays a very crucial role in diagnosing and early intervention and treating any ailment. Bone FNAC also is beneficial for identifying the treatment modality. It should be used on regular basis for bone lesions.
The Influence of Tiktok and Youtube Social Media use on the Young Generation in the Jakarta Special Capitol
Authors: Subiakto Vania Utamie
Published: February 2023

The study will identify how far the use of social media TikTok and YouTube has influenced the self-quality of the young generation in the Jakarta Special Capitol. Thus, the objective of the study is to identify the influence of the use of the social media TikTok and YouTube on the self-quality of the young generation in Jakarta Special Capitol. In conducting the study, the Stimulus-Response Theory has been implemented because in the use of the social media TikTok and YouTube the public or the young generations will define the initiative upon their alternatives with regards to the needs of satisfaction on certain media. Both the public and the young generations are provided with the decision on the needs within the media society which has been known to compete with one another. As a result, the positivist paradigm has been adopted in the study. Then, the study itself took place in Jakarta Special Capitol from February until March 2022. The design that the researchers have adopted in the study is the causal method whereas the data analysis within the study is conducted by using the PLS. The results of the study show the influence of Tiktok and YouTube social media platforms on the self-quality of the young generations in the Jakarta Special Capitol. The coefficient value of TikTok (X1) against the self-quality of the young generation (Y) is -0.038. Hence, it can be concluded that the social media platform TikTok (X1) has a negative and insignificant influence on the self-quality of the young generations in Jakarta Special Capitol. On the contrary, the coefficient value of YouTube (X2) against the self-quality of the young generation (Y) is 0.687 with a T-statistics value of 6.762 and a p-value of 0.000. Based on these results, it can be concluded that the social media platform YouTube (X2) has a positive and significant influence on the self-quality of the young generations in Jakarta.
Analisis Usability Aplikasi Mobile MyUMM Student Dengan Menggunakan Metode USE Questionnaire
Authors: Anhar Anhar , Suharso Wildan , Rahmayanti Vinna
Published: February 2023

Penelitian ini bertujuan untuk mengetahui tingkat usability Aplikasi MyUMM menggunakan metode USE Questionnaire. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian korelasi. Populasi dan sampel pada penelitian ini adalah mahasiswa Fakultas Tehnik,Jurusan Informatika  Universitas Muhammadiyah Malang dengan jumlah 203 mahasiswa. Teknik pengambilan sampel menggunakan teknk simple random sampling. Pengumpulan data dilakukan menggunakan kuesioner online dan offline. Uji validitas per butir soal kuesioner dihitung dengan rumus product moment pearson correlation dan uji reliabilitas menggunakan Croanbach Alpha. Pengujian hipotesis menggunakan uji asumsi klasik dan regresi linear berganda.Hasil penelitian menunjukkan terdapat hubungan yang signifikan semua variabel X terhadap Y yang dilakukan secara simultan. Sedangkan pengujian yang dilakukan secara parsial menunjukkan bahwa semua variabel x berpengaruh terhadap variabel Y.
Examining GRIT Predictors of Career Preparation Behavior of College Students with Disabilities: Correlation and multiple regression analysis
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Shinyoung , Park Jinseok
Published: February 2023

Objectives This study examined the correlation and predictive relationship between GRIT (Growth, Resilience, Intrinsic motivation, and tenacity) scores and the level of career preparation behavior of college students with disabilities in Korea.
Methods Two measures, the Short GRIT Scale (GRIT-S) and the career preparation behavior scale, were used to collect score data of 118 college students with disabilities at D University. The researchers analyzed the data using Pearson correlation and multiple regression analysis.
Results This study’s findings showed that 1) There were differences in the scores of GRIT and career behavior preparation depending on gender, year(s) of study, and disability category, 2) Positive correlations existed between partial GRIT and career preparation behavior scores, and 3) Higher GRIT scores predicted positive career preparation behavior, which explained 20.5% of the total variance.
Conclusions Based on the findings, the researchers discussed influencing factors of individualized support programs for the success of students with disabilities in higher education.
Adult Continuing Education Learners Consideration of non-face-to-face online lecture cases: Focusing on video recording and synchronous video conferencing lecture
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Ha Won
Published: February 2023

Objectives The purpose of this study is to analyze the lecture preparation, lecture characteristics, and lecture satisfaction of adult continuing education learners in childcare sites in the process of converting in person to online lectures.
Methods To this end, this author examined the syllabus, LMS and SNS materials, PPT, and learners' self-report data. ‘The guidance of child life’ as a synchronous video conferencing lecture and ‘Advanced Child Counseling’ as a video recording lecture conducted in the second semester of 2021 with Merriam qualitative analysis. The participant was a total of 65 adult continuing education learners of the Department of Industrial Education, composed of faculty and staff of daycare centers at C University in Seoul, and conducted a satisfaction survey using questionnaires.
Results First, video-recorded lectures take less time than face-to-face lectures, requiring instructors to mount various materials before class, while synchronous video conferencing lecture, require both instructors and adult continuing education learners to have prepared online skills before class. Second, video-recorded lectures have the advantage of being able to use time and space freely, but in order to compensate for the lack of online class time, weekday assignments are a burden for adult continuing education learners, while synchronous video conferencing lecture has the advantage of freely using space and giving social presence, but various motivational factors and technical devices that can increase immersion due to low class concentration should be supplemented. Third, in the class satisfaction survey, it was found that adult continuing education learners expressed higher satisfaction with video-recorded lectures than with synchronous video conferencing lecture.
Conclusions Through this study, it was found that for non-face-to-face online classes of adult continuing education learners, it is necessary to build infrastructure for uploading various materials and strengthen online technology, and online teaching methods should be implemented for high-quality interaction between ‘instructor-learners’ in non-face-to-face situations. In addition, as an adult continuing education learner who works in a children's daycare center during the day, it was an effective medium to use video-recorded lecture, including various motivational elements. It is hoped that this study will contribute to the more efficient operation of non-face-to-face online lectures for adult continuing education learners at universities.
The impact of COVID-19 awareness on career-ready behavior in college students: Focusing on the mediating effect of perceived career barriers
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kang Ha-Na , Kim Yun-Hee
Published: February 2023

Objectives This study attempted to determine whether perceived career barriers act as parameters in the relationship between perception of COVID-19 and college students' career preparation behavior.
Methods For this purpose, a survey was conducted on 311 men and women attending universities in Busan who understood the purpose and procedure of the study and agreed to participate in the study from April 26 to 30, 2021 using the perceived career barrier and career preparation behavior scale. The collected data were analyzed using the PROCESS macro Model No. 4 model of SPSS Process V3.5, Hayes (2017).
Results The results of the study are as follows. First, it was found that perception of COVID-19 and perceived career barriers had a statically significant correlation, and perceived career barriers and career preparation behavior had a negative significant correlation. Second, while the direct effect of perception of COVID-19 on college students' career preparation behavior did not have a significant effect, it was verified that the indirect effect on college students' career preparation behavior was significant through the perceived career barrier. In other words, it was found that the perceived career barrier had a complete mediating effect in the relationship between the perception of COVID-19 and the career preparation behavior of college students.
Conclusions The higher the anxiety caused by the COVID-19 situation, the higher the perception of career barriers, which can suppress career preparation behavior, suggested implications related to interventions to promote college students' career preparation behavior in the COVID-19 situation, and finally discussed the limitations of the study.