bluuebunny/crossref_metadata_2025 huggingface dataset:
An Insight on Salting‐out Assisted Liquid–Liquid Extraction for Phytoanalysis
Authors: Valente Inês M. , Moreira Manuela M. , Neves Pâmela , da Fé Thiago , Gonçalves Luís M. , Almeida Paulo J. , Rodrigues José A.
Published: January 2017

Introduction

Salting‐out assisted liquid–liquid extraction (SALLE) is a technique that, although simple and not requiring any complex equipment, is very powerful and versatile. It has obtained growing interest in bioanalysis particularly when combined with chromatographic techniques.

Objectives

Herein, fennel seeds (Foeniculum vulgare Mill.) were used as a case‐study to show the application of SALLE in phytochemical analysis.

Material and Methods

SALLE combined with HPLC‐UV‐MS/MS and GC–MS.

Results

By HPLC‐UV‐MS/MS analysis of the organic extract it was possible to identify various phenolic compounds, including quercetin derivatives, caffeic acid, p‐coumaric acid and chlorogenic acid. The main compounds identified by GC–MS were estragole, fenchone, anisaldehyde, anethole, benzaldehyde, camphor and apiole.

Conclusion

HPLC and GC analysis of the extracts showed that it is possible to isolate, in only one step, a wide range of compounds with distinct properties, allowing a detailed phytochemical analysis. Copyright © 2017 John Wiley & Sons, Ltd.
Regret and fear in prostate cancer: The relationship between treatment appraisals and fear of recurrence in prostate cancer survivors
Authors: Maguire Rebecca , Hanly Paul , Drummond Frances J. , Gavin Anna , Sharp Linda
Published: January 2017

Objective

Fear of recurrence (FOR) is a key concern among survivors of all cancers. In prostate cancer, FOR varies with health and treatment type, but little is known about how survivors' appraisals of their treatment, and in particular, their level of regret over treatment decisions may affect this.

Methods

A total of 1229 prostate cancer survivors between 2‐ and 5‐years postdiagnosis were invited to complete a postal questionnaire including a FOR scale, Decisional Regret Scale, and the European Organization for Research and Treatment of Cancer QLQ C30 health‐related quality of life (HRQoL) instrument. Multiple regression analysis explored the impact of 3 blocks of factors on FOR: (1) demographic characteristics and disease extent, (2) primary treatment received and health status (treatment side effects and HRQoL), and (3) treatment appraisals, specifically satisfaction with information received regarding treatment and level of regret experienced over treatment decisions.

Results

The final multivariable model explained 27% of variance on FOR. Significant correlates of lower FOR included having localised disease, having undergone an invasive treatment, as well as health status (higher HRQoL and fewer ongoing side effects). Beyond this, appraisals of treatment significantly contributed to the model: More decisional regret and lower satisfaction with information received were associated with higher FOR.

Conclusion

These findings suggest that FOR may be mitigated by providing survivors with more information regarding treatment choices and the treatment itself so that men can make well‐informed decisions and experience less future regret.

Sensitivity analysis for variables predicting FOR among prostate cancer survivors is not suspected of having a recurrence.
Generalizability analysis for clinical trials: a simulation study
Authors: Wang Wei , Ma Ying , Huang Yangxin , Chen Henian
Published: January 2017

Subjects are rarely selected on a random basis from a well‐defined patient population of interest into a clinical trial, with women, children, the elderly, and those with common comorbidities who are frequently underrepresented. Decades of clinical experience have demonstrated that the application of trial findings to individual patients is permissible by using efficacy as a measure of effectiveness and assuming that the characteristics of patients are sufficiently similar. In order to investigate this issue in greater depth, we simulated a patient population with treatment effect size of 0.5 (Cohen's d) and five covariates that included gender, health insurance, comorbidity, age, and motivation. To demonstrate how selection of patients for a clinical trial can bias the results when treatment effect varies across individuals, we created 50 nonrandom clinical trials based on this patient population and showed relative bias to range from 1.68% to 99.70%. We calculated and evaluated three indexes: C‐statistics, standardized mean difference (SMD), and Tipton's index (β) of generalization for the 50 nonrandom trials. Findings indicated that (i) the ranges were 0.56–0.98, 0.23–11.17, and 0.99–0.73 for C‐statistics, SMD, and β, respectively, when treatment effect bias increased from 1.68% to 99.70% and (ii) C‐statistics < 0.86, SMD < 1.95, and β > 0.91 when treatment effect bias <50%. Recommendations are made using existing generalization indexes on the basis of our simulation results. An example from a real clinical trial is provided for illustration. Copyright © 2017 John Wiley & Sons, Ltd.
Prevalence of HER2 Positivity and Its Clinicopathological Correlation in Locally Advanced/Metastatic Gastric Cancer Patients in Malaysia
Authors: Rajadurai Pathmanathan , Fatt Ho Kean , Ching Foo Yoke
Published: January 2017

Purpose

Human epidermal growth factor receptor 2 (Erbb2/HER2) overexpression, which was previously detected in invasive breast cancer, has now been implicated in advanced gastric cancer (GC) and gastroesophageal junction cancer (GEC). A study was conducted to determine the rate of HER2 positivity in patients with locally advanced or metastatic GC and GEC in Malaysia and to assess the impact of various demographic and clinical parameters on HER2 positivity.

Methods

A total of 228 adult patients with GC or GEC were enrolled from Subang Jaya Medical Centre, Malaysia, for retrospective (210) and prospective study. All patients were subjected to the HER2 immunohistochemistry test using an FDA-approved, standardized test kit. Carcinomas scoring 2+ on immunohistochemistry were further tested with HER2 in situ hybridization (ISH) using an FDA-approved test kit.

Results

The overall rate of HER2 positivity in the population studied was 24.6% (n = 56). The rate was significantly higher in men than in women (29.6 vs. 16.3%;p = 0.024). HER2 overexpression was significantly more common in diffuse type than in intestinal type of tumors (39.8 vs. 14.9%;p < 0.001). In our study, out of 56 samples, 44 (78.6%) were considered for gene amplification testing, out of which 40 (90.1%) samples showed gene amplification. There was no statistically significant correlation between HER2 positivity and patient age, race, tumor location, tumor differentiation, and TNM staging.

Conclusions

HER2 overexpression was evident in nearly 25% of the Malaysian patients with locally advanced or metastatic gastric cancer. The overexpression correlated significantly with male gender and diffuse-type tumors. The majority of the IHC-positive tumors demonstrated c-erb2gene amplification and this finding reached statistical significance.
Simulation of ventricular rate control during atrial fibrillation using ionic channel blockers
Authors: Inada Shin , Shibata, MD, PhD Nitaro , Iwata, PhD Michiaki , Haraguchi, PhD Ryo , Ashihara MD, PhD Takashi , Ikeda, MD, PhD Takanori , Mitsui, PhD Kazuyuki , Dobrzynski, PhD Halina , Boyett, PhD Mark R. , Nakazawa, PhD Kazuo
Published: January 2017

Background

The atrioventricular (AV) node is the only compartment that conducts an electrical impulse between the atria and the ventricles. The main role of the AV node is to facilitate efficient pumping by conducting excitation slowly between the two chambers as well as reduce the ventricular rate during atrial fibrillation (AF).

Methods

Using computer simulations, we investigated excitation conduction from the right atrium to the bundle of His during high‐rate atrial excitation with or without partial blocking of the calcium or potassium ionic current.

Results

Our simulations revealed differences in rate reduction and repolarization effects between calcium and potassium current blocking and high degree of potassium current blocking required to reduce the ventricular rate during AF.

Conclusions

Our simulation results explain why potassium current blockers are not recommended for controlling ventricular rate during AF.
Ultrashort pulse capability at the L2I high intensity laser facility
Authors: Figueira Gonçalo , Alves Joana , Dias João M. , Fajardo Marta , Gomes Nuno , Hariton Victor , Imran Tayyab , João Celso P. , Koliyadu Jayanath , Künzel Swen , Lopes Nelson C. , Pires Hugo , Ruão Filipe , Williams Gareth
Published: January 2017

The Laboratory for Intense Lasers (L2I) is a research centre in optics and lasers dedicated to experimental research in high intensity laser science and technology and laser plasma interaction. Currently the laboratory is undergoing an upgrade with the goal of increasing the versatility of the laser systems available to the users, as well as increasing the pulse repetition rate. In this paper we review the current status of the laser research and development programme of this facility, namely the upgraded capability and the recent progress towards the installation of an ultrashort, diode-pumped OPCPA laser system.
Inertial regimes in a curved electromagnetically forced flow
Authors: Boisson J. , Monchaux R. , Aumaître S.
Published: January 2017

We investigated experimentally the flow driven by a Lorentz force induced by an axial magnetic field $\boldsymbol{B}$ and a radial electric current $I$ applied between two fixed concentric copper cylinders. The gap geometry corresponds to a rectangular section with an aspect ratio of $\unicode[STIX]{x1D702}=4$ and we probe the azimuthal and axial velocity profiles of the flow along the vertical axis by using ultrasonic Doppler velocimetry. We have performed several runs at moderate magnetic field strengths, corresponding to moderate Hartmann numbers $M\leqslant 300$. At these forcing parameters and because of the geometry of our experimental device, we show that the inertial terms are not negligible and an azimuthal velocity that depends on both $I$ and $B$ is induced. From measurements of the vertical velocity we focus on the characteristics of the secondary flow: the time-averaged velocity profiles are compatible with a secondary flow presenting two pairs of stable vortices, as pointed out by previous numerical studies. The flow exhibited a transition between two dynamical modes, a high- and a low-frequency one. The high-frequency mode, which emerges at low magnetic field forcing, corresponds to the propagation in the radial $r$-direction of tilted vortices. This mode is consistent with our previous experiments and with the instability described in Zhao et al. (Phys. Fluids, vol. 23 (8), 2011, 084103) taking place in an elongated duct geometry. The low-frequency mode, observed for high magnetic field forcing, consists of large excursions of the vortices. The dynamics of these modes matches the first axisymmetric instability described in Zhao & Zikanov (J. Fluid Mech., vol. 692, 2012, pp. 288–316) taking place in an square duct geometry. We demonstrated that this transition is controlled by the inertial magnetic thickness $H^{\prime }$ which is the characteristic length we introduce as a balance between the advection and the Lorentz force. The key point here is that when the inertial magnetic thickness $H^{\prime }$ is comparable to one geometric characteristic length ($H/2$ in the vertical or $\unicode[STIX]{x0394}r$ in the radial direction) the corresponding mode is favoured. Therefore, when $H^{\prime }/(H/2)\approx 1$ we observe the high-frequency mode taking place in an elongated duct geometry, and when $H^{\prime }/\unicode[STIX]{x0394}r\approx 1$ we observe the low-frequency mode taking place in square duct geometry and high magnetic field.
Lengua de los indios, lengua española:Religious Conversion and the Languages of New Spain, ca. 1520–1585
Authors: Wasserman-Soler Daniel I.
Published: January 2017

This article examines the language policies of sixteenth-century Mexico, aiming more generally to illuminate efforts by Mexican bishops to foster conversions to Christianity. At various points throughout the colonial era, the Spanish Crown and the Catholic Church propagated the use of Castilian among Amerindians; leaders of these institutions, however, also encouraged priests to study indigenous languages. That Spanish authorities appear to have never settled on a firm language policy has puzzled modern scholars, who have viewed the Crown and its churchmen as vacillating between “pro-indigenous” and “pro-Castilian” sentiments. This article suggests, however, that Mexico's bishops intentionally extended simultaneous support to both indigenous languages and Castilian. Church and Crown officials tended to avoid firm ideological commitments to one language; instead they made practical decisions, concluding that different contexts called for distinct languages. An examination of the decisions made by leading churchmen offers insight into how they helped to create a Spanish-American religious landscape in which both indigenous and Spanish elements co-existed.
FORUM ON ROBERT BARTLETT'S WHY CAN THE DEAD DO SUCH GREAT THINGS?: SAINTS AND WORSHIPPERS FROM THE MARTYRS TO THE REFORMATION: Introductory Remarks
Authors: Sterk Andrea
Published: January 2017

Pondering the miraculous deeds of the early Christian saints and martyrs in his City of God, St. Augustine queried, “Why can the dead do such great things?”1 Robert Bartlett's magisterial study takes up this question by examining the veneration of the holy dead from the age of the martyrs through the Protestant Reformation. While its center of gravity is medieval Europe, the book's long scope and comparative dimensions make it relevant to historians and scholars of religion across a broad chronological and geographic spectrum. Alongside its erudition, Bartlett's study is also remarkably accessible—full of engaging stories, good humor, and profound insight into human nature as well as social practice.
Scripture, Time, and Authority among Early Disciples of Christ
Authors: Perry Seth
Published: January 2017

This article explores the relationship between the idealization of the Bible and the material characteristics of printed bibles among the Disciples of Christ in the early nineteenth century. The Disciples were founded on the principles of biblical primitivism: they revered the “pure” Bible as the sole source for proper faith and practice. The tenacity with which Disciples emphasized their allegiance to an idealized, timeless Bible has obscured their attention to its physical manifestations and use as printed scripture. The timeless authority of the Bible was entangled with the historical contingencies of mere bibles, and the ways in which they dealt with these tensions offer important perspective on nineteenth-century bible culture. Scholars have treated primitivism as an ahistorical impulse—the idealization of the New Testament church as a mythical sacred era outside of time that could be perpetually inhabited. By contrast, through an examination of the New Testaments edited and published by Disciples leader Alexander Campbell and the heavily-annotated preaching bible of Thomas Allen, an early Disciples preacher, I argue that in seeking to recover the New Testament era through historicized understandings of scripture, primitivists like Campbell and Allen situated the early church itself firmly within historical, not primordial, time.
Saints, Martyrs, and the Reformation: Reflections on Robert Bartlett's Why Can the Dead Do Such Great Things?
Authors: Cameron Euan
Published: January 2017

Robert Bartlett's book on the cult of saints in the Middle Ages clearly constitutes a major achievement. Its scope is vast; its approach ranges from the chronological to the thematic; it embraces many cultural, as well as theological and religious, aspects of the subject. Finally, it is informed by a rich comparative vision that includes wide-ranging discussion of other religions.
Understanding the low uptake of bone-anchored hearing aids: a review
Authors: Powell R , Wearden A , Pardesi S M , Green K
Published: January 2017

Background:

Bone-anchored hearing aids improve hearing for patients for whom conventional behind-the-ear aids are problematic. However, uptake of bone-anchored hearing aids is low and it is important to understand why this is the case.

Method:

A narrative review was conducted. Studies examining why people accept or decline bone-anchored hearing aids and satisfaction levels of people with bone-anchored hearing aids were reviewed.

Results:

Reasons for declining bone-anchored hearing aids included limited perceived benefits, concerns about surgery, aesthetic concerns and treatment cost. No studies providing in-depth analysis of the reasons for declining or accepting bone-anchored hearing aids were identified. Studies of patient satisfaction showed that most participants reported benefits with bone-anchored hearing aids. However, most studies used cross-sectional and/or retrospective designs and only included people with bone-anchored hearing aids.

Conclusion:

Important avenues for further research are in-depth qualitative research designed to fully understand the decision-making process for bone-anchored hearing aids and rigorous quantitative research comparing satisfaction of people who receive bone-anchored hearing aids with those who receive alternative (or no) treatments.
Drunken poets and new women: Consuming tradition and modernity in colonial Vietnam
Authors: Sasges Gerard
Published: January 2017

This article uses the lens of alcohol as a means of exploring the experiences and anxieties of Vietnamese ‘colonial modernity’ and the way it was mutually constituted with ‘colonial tradition’. The production, consumption, and meaning of alcohol in Vietnam were all profoundly altered as the state's contested attempts to control the market for rice liquor interacted with the growing availability of imports like wine, champagne, and cognac. While these new products would become ideal symbols of modernity and markers of distinction, at the same time reinvented traditions surrounding what the French called ‘native’ and the Vietnamese called ‘our’ alcohol would become linked to evolving notions of community and nation.
Friction within harmony: Everyday dynamics and the negotiation of diversity in Yogyakarta, Indonesia
Authors: de Jong Edwin , Twikromo Argo
Published: January 2017

Most studies on diversity in Southeast Asia focus on the nation-state, with much less attention given to everyday encounters and the negotiation of diversity in local contexts. This article investigates the discourses and practices of various actors in the historically tolerant, generally peaceful, and diverse city and special region of Yogyakarta, Indonesia. This study examines this ethnic, religious and cultural diversity and illustrates the negotiations among various interest groups and actors that strive to maintain this balance, or sometimes to strategically disrupt it. As such, the findings offer a different way to understand and interrogate the challenges confronting present-day diversity both on a local level in Yogyakarta, and also for Indonesia and Southeast Asia at large.
Quezon's City: Corruption and contradiction in Manila's prewar suburbia, 1935–1941
Authors: Pante Michael D.
Published: January 2017

Quezon City was founded in 1939 as a planned city and envisioned as the future capital of the Philippines, which was anticipating its independence in a few years. Led by President Manuel Quezon, Philippine politicians conferred upon the city narratives of nationhood and social justice to make it the best spatial representation of a nation-in-waiting. However, underneath these state-centric ideologies was the authoritarianism of the Quezon regime, which used urban politics to centralise power. But far from being a symbol of the President's undisputed dominance, Quezon City's inherent contradictions became weak points in the city's official narrative.
David Marr's Vietnamese Revolution
Authors: Miller Edward
Published: January 2017

During the fall of 1962, the American war correspondent Richard Tregaskis spent three months in South Vietnam. InVietnam diary, published the following year, Tregaskis offered vivid descriptions of his experiences, which included joining South Vietnamese army troops on combat missions against ‘Viet Cong’ fighters, as well as observing an election inside one of the Saigon government's newly built ‘strategic hamlets’. But the main purpose ofVietnam diarywas to detail the author's many encounters with Americans in South Vietnam — specifically the US soldiers, marines, and other military personnel serving as advisers to the South Vietnamese Army. Tregaskis greatly admired these Americans, whom he portrayed as indomitable Cold Warriors. He was particularly impressed with Lieutenant Dave Marr, a Marine intelligence officer he met at a US base in the city of Da Nang. Lt Marr, whom Tregaskis described as a ‘slim blond youth’ from California, spoke excellent Vietnamese, thanks to a year of intensive language training. He also displayed a marked ‘enthusiasm for things Vietnamese’. Tregaskis noted that Marr was rather less optimistic than many of his peers about the prospects for success against the communist enemy. ‘The best you can say is that we're holding our own,’ the marine told the journalist.
Suffering with dementia: the other side of “living well’’
Authors: Bartlett Ruth , Windemuth-Wolfson Lore , Oliver Keith , Dening Tom
Published: January 2017

In this editorial, we challenge the current understanding of “Living Well with Dementia.” Such discourse introduces the possibility of not living well with the condition or even of “living badly with dementia.” Numerous words might be relevant here – grief, pain, anguish, depression – but in this editorial we consciously use the word “suffering.” This term is used for two reasons; one, because it captures the attributes of other more limited words, and, two because the language of “suffering” is contentious, making it suitable for debate. We speak of suffering, not to deny the positive aspects of life with dementia or to concentrate just on the negative, but to redress the balance that is disturbed by a relentlessly positive view of living with the condition. Our aim is to promote a more realistic understanding of the dementia experience, one based on actualities and evidence rather than presumption and sentiment.
Delivery as Trauma: A Prospective Time-Cohort Study of Maternal and Perinatal Mortality in Rural Cambodia
Authors: Houy Chandy , Ha Sam Ol , Steinholt Margit , Skjerve Eystein , Husum Hans
Published: January 2017

Objective

The majority of maternal and perinatal deaths are preventable, but still women and newborns die due to insufficient Basic Life Support in low-resource communities. Drawing on experiences from successful wartime trauma systems, a three-tier chain-of-survival model was introduced as a means to reduce rural maternal and perinatal mortality.

Methods

A study area of 266 villages in landmine-infested Northwestern Cambodia were selected based on remoteness and poverty. The five-year intervention from 2005 through 2009 was carried out as a prospective study. The years of formation in 2005 and 2006 were used as a baseline cohort for comparisons with later annual cohorts. Non-professional and professional birth attendants at village level, rural health centers (HCs), and three hospitals were merged with an operational prehospital trauma system. Staff at all levels were trained in life support and emergency obstetrics.

Findings

The maternal mortality rate was reduced from a baseline level of 0.73% to 0.12% in the year 2009 (95% CI Diff, 0.27-0.98; P<.01). The main reduction was observed in deliveries at village level assisted by traditional birth attendants (TBAs). There was a significant reduction in perinatal mortality rate by year from a baseline level at 3.5% to 1.0% in the year 2009 (95% CI Diff, 0.02-0.03; P<.01). Adjusting maternal and perinatal mortality rates for risk factors, the changes by time cohort remained a significant explanatory variable in the regression model.

Conclusion

The results correspond to experiences from modern prehospital trauma systems: Basic Life Support reduces maternal and perinatal death if provided early. Trained TBAs are effective if well-integrated in maternal health programs.

HouyC,HaSO,SteinholtM,SkjerveE,HusumH.Delivery as trauma: a prospective time-cohort study of maternal and perinatal mortality in rural Cambodia.Prehosp Disaster Med.2017;32(2):180–186.
Bioreducible cross-linked core polymer micelles enhance in vitro activity of methotrexate in breast cancer cells
Authors: Gulfam Muhammad , Matini Teresa , Monteiro Patrícia F. , Riva Raphaël , Collins Hilary , Spriggs Keith , Howdle Steven M. , Jérôme Christine , Alexander Cameron
Published: January 2017

PEG-poly(caprolactone) co-polymers with disulfide-linked cores are highly efficient for delivery of the anti-cancer drug methotrexate in vitro.
Catalytic hydrogenation of CO2 to methane over supported Pd, Rh and Ni catalysts
Authors: Martin Natalia M. , Velin Peter , Skoglundh Magnus , Bauer Matthias , Carlsson Per-Anders
Published: January 2017

CO2 methanation over Rh/Al2O3, Rh/CeO2 and Ni/CeO2 at 350 °C highlighting the different surface speciation during reaction.
Improving the catalytic efficiency of carbon-based active sites by trace oxide promoters for highly productive olefin synthesis
Authors: Zhou Hang , Lou Hui , Lu Weimin
Published: January 2017

The catalytic ODH activation energy on CNTs significantly decreased by the introduction of metal oxides. The propane turn-over efficiency of each original carbon-based active site consequently increased exponentially.
A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics
Authors: Sarkar Paramita , Yarlagadda Venkateswarlu , Ghosh Chandradhish , Haldar Jayanta
Published: January 2017

In this review, inhibitors of the cell wall biosynthetic pathway are presented with a focus on the recent advances in glycopeptide antibiotics.
Deracemisations under kinetic and thermodynamic control
Authors: Palmans A. R. A.
Published: January 2017

Various methods of deracemising mixtures of enantiomers are discussed that permit to isolate one of the enantiomers in essentially quantitative yield.
Programmable and reversible assembly of soft capillary multipoles
Authors: Bae Jinhye , Bende Nakul P. , Evans Arthur A. , Na Jun-Hee , Santangelo Christian D. , Hayward Ryan C.
Published: January 2017

The capillary assembly of stimulus-responsive hydrogel particles with programmed multipolar interactions defined by their prescribed three-dimensional (3D) shapes is demonstrated.
A folding-directed catalytic microenvironment in helical dynamic covalent polymers formed by spontaneous configuration control
Authors: Li Wenfang , Zhang Chenyang , Qi Shuaiwei , Deng Xiaoli , Wang Wei , Yang Bing , Liu Junqiu , Dong Zeyuan
Published: January 2017

Helical dynamic covalent polymers with a folding-directed hollow tubular structure were investigated for catalysis.
Manipulating energy storage characteristics of ultrathin boron carbide monolayer under varied scandium doping
Authors: Naqvi S. R. , Hussain T. , Panigrahi P. , Luo W. , Ahuja R.
Published: January 2017

We report, for the first time we believe, a detailed investigation on hydrogen storage efficiency of scandium (Sc) decorated boron carbide (BC3) sheets using spin-polarized density functional theory (DFT).
Cadmium and lead remediation using magnetic and non-magnetic sustainable biosorbents derived from Bauhinia purpurea pods
Authors: Sharma Rupa , Sarswat Ankur , Pittman Charles U. , Mohan Dinesh
Published: January 2017

Bauhinia purpurea (Kaniar) pods were dried, powdered, and utilized for cadmium and lead removal.
First step towards a model system of the drug delivery network based on amide-POSS nanocarriers
Authors: John Łukasz , Malik Mariola , Janeta Mateusz , Szafert Sławomir
Published: January 2017

We present the synthetic and release aspects of a novel drug delivery system (DDS) based on amido-functionalized POSS. DDS after drug release hydrolyses at pH = 7.40 to non-toxic products such as carboxylic acid salts and aminopropyl-POSS.
Anti-neuroinflammatory asarone derivatives from the rhizomes of Acorus tatarinowii
Authors: Qin Da-Peng , Feng Xiao-Lin , Zhang Wei-Yang , Gao Hao , Cheng Xiao-Rui , Zhou Wen-Xia , Yu Yang , Yao Xin-Sheng
Published: January 2017

A novel 7-O-7′ type mesomeric neolignan,meso-asarolignan A (1), six pairs of new neolignan enantiomers, (±)-asarolignan B–G (2a/2b,3a/3b,4–6,7a/7b), along with 16 known analogues (8–23) were isolated from the rhizomes ofAcorus tatarinowii.
Quantum mechanical investigation into the electronic transport properties of a memantine-functionalized gold nanopore biosensor for natural and mutated DNA nucleobase detection
Authors: Kole Abhisek , Radhakrishnan K.
Published: January 2017

Quantum mechanical studies of the electronic transport properties of a memantine-functionalized gold nanopore biosensor for natural and mutated DNA nucleobase detection are reported.
A new insight into the rechargeable mechanism of manganese dioxide based symmetric supercapacitors
Authors: Chen Hongyuan , Zeng Sha , Chen Minghai , Zhang Yongyi , Li Qingwen
Published: January 2017

In symmetric supercapacitors based on MnO2, only MnO2 on the negative electrode serves as the electrochemically active material. MnO2 on the negative electrode dissolves and re-deposites on the positive electrode, thus induces a decrease in specific capacitance.
Thermoelectric enhancement in sliver tantalate via strain-induced band modification and chemical bond softening
Authors: Li Jun , Ma Zuju , Wu Kechen
Published: January 2017

Herein, we report the strain-induced enhancement of the Seebeck coefficient, caused by valence band modification and thermal conductivity reduction due to bond softening.
Automated reaction progress monitoring of heterogeneous reactions: crystallization-induced stereoselectivity in amine-catalyzed aldol reactions
Authors: Rougeot Céline , Situ Henry , Cao Blessing Huynh , Vlachos Vaso , Hein Jason E.
Published: January 2017

A prototype solution/slurry automated sampling instrument reveals the origin of diastereoselectivity in this organocatalyzed aldol reaction.
Ultrathin and large-sized vanadium oxide nanosheets mildly prepared at room temperature for high performance fiber-based supercapacitors
Authors: Hua Li , Ma Zhongyuan , Shi Peipei , Li Li , Rui Kun , Zhou Jinyuan , Huang Xiao , Liu Xiang , Zhu Jixin , Sun Gengzhi , Huang Wei
Published: January 2017

Ultrathin V2O5nanosheets with large lateral sizes were successfully prepared and used for high performance fiber-based supercapacitors.
Phosphonate-chitosan functionalization of a multi-channel hydroxyapatite scaffold for interfacial implant-bone tissue integration
Authors: Abueva Celine D. G. , Jang Dong-Woo , Padalhin Andrew , Lee Byong-Taek
Published: January 2017

Phosphonate-chitosan functionalization of a multi-channel hydroxyapatite scaffold as a new approach to improve interfacial implant-bone tissue integration.
Thermal tolerance of allis shad (Alosa alosa) embryos and larvae: Modeling and potential applications
Authors: Jatteau Philippe , Drouineau Hilaire , Charles Katia , Carry Laurent , Lange Frédéric , Lambert Patrick
Published: January 2017

The objective of this study was to assess the potential effects of climate change on the survival of allis shad early life history stages. Embryos and larvae were exposed to temperatures ranging from 5 to 35 °C. No embryonic survival was recorded at extreme temperatures (≤10 and ≥30 °C), and no larval survival was observed at 5 or 35 °C. Based on these experimental results, a survival model was developed to predict survival rates at different temperatures for embryos and larvae up to 14 days post hatch. The model confirmed that embryonic daily survival is more impacted by temperature than larval survival. The highest survival rates (greater than 80%) were found for temperatures between 15.7 and 25.6 °C for embryos and between 14.6 and 26.7 °C for larvae. This survival model can be used to explore the impact of temperature on recruitment of allis shad in southern France. Preliminary analysis from two different rivers suggests that cold temperatures may have a strong impact on embryonic and larval survival.
POD and Fourier analyses of a fluid-structure-acoustic interaction problem related to interior car noise
Authors: Gaudard Éric , Druault Philippe , Marchiano Régis , Van Herpe François
Published: January 2017

In order to approach a flow configuration revealing the aerodynamic noise contribution in the interior of road vehicles due to the A-pillar vortex, a numerical simulation of a Forward Facing Step (FFS) coupled with a vibrating structure is performed. This numerical study is based on a weak coupling of three solvers to compute (i) the flow field in interaction with the FFS, (ii) the vibration of the structure and (iii) the acoustic radiation in the open cavity. The purpose of this work is then to evaluate the ability of two different post-processing methods: Proper Orthogonal Decomposition and Fourier Decomposition to identify the origin of the noise radiated into a cavity surrounded by an unsteady flow. Fourier and POD decompositions are then successively performed to extract the part of the aeroacoustic wall pressure field impacting the upper part of an upward step mainly related to the radiated acoustic pressure in the cavity. It is observed that the acoustic part, extracted from the wavenumber frequency decomposition (Fourier analysis) of the wall pressure field generates a non-negligible part of the interior cavity noise. However, this contribution is of several orders smaller than the one related to the aerodynamic part of the pressure field. Moreover, it is shown that the most energetic part of the pressure field (POD analysis) is due to the shear flapping motion and mainly contributes to the low-frequency noise in the cavity. Such post-processing results are of particular interest for future analyzes related to the noise radiated inside a car.
Examining Mortality and Rejection in Combined Heart–Lung Transplantations
Authors: Taghavi Sharven , Jayarajan Senthil , Ambur Vishnu , Wheatley Grayson , Kaiser Larry , Toyoda Yoshiya , Kadakia Sagar
Published: January 2017

Background There is a paucity of data on outcomes related to combined heart–lung transplantations (HLTs). Our objective was to identify variables associated with mortality and rejection in HLT.

Methods The United Network for Organ Sharing database was reviewed for HLT performed between 1993 and 2008. Long-term survivors (survival > 5 years) were compared with short-term survivors (survival < 5 years). Factors associated with rejection were examined. Risk-adjusted multivariable Cox's proportional hazards regression analysis was performed to examine variables associated with mortality and rejection.

Results Multivariable analysis revealed that recipient male gender was associated with mortality at 1 year (hazard ratio [HR]: 1.68, 95% confidence interval [CI]: 1.11–2.54, p = 0.01) and 5 years (HR: 1.41, 95% CI: 1.05–1.89, p = 0.02). Preoperative extracorporeal membrane oxygenation (ECMO) was associated with mortality at 1 year (HR: 7.55, 95% CI: 2.55–22.30, p < 0.01) and 5 years (HR: 3.14, 95% CI: 1.19–8.32, p = 0.02). Preoperative mechanical ventilation (MV) was associated with mortality at 1 year (HR: 3.51, 95% CI: 1.77–6.98, p < 0.01) and at 5 years (HR: 2.70, 95% CI: 1.51–4.85, p < 0.01). Multivariable analysis showed that male gender (HR: 1.78, 95% CI: 1.03–3.09, p = 0.04) and cytomegalovirus (CMV) positivity in the recipient and donor (HR: 3.09, 95% CI: 1.59–6.01, p < 0.01) were associated with rejection. Clinical infection in the donor (HR: 2.05, 95% CI: 1.16–3.61, p = 0.01) was also associated with rejection.

Conclusion Survival was affected by recipient male sex and need for preoperative ECMO or MV. Risk factors for rejection included male sex, CMV positivity in the donor and recipient, and donor with clinical infection.
Video-Assisted Laser Resection of Lung Metastases—Feasibility of a New Surgical Technique
Authors: Meyer Christian , Bartsch Detlef , Mirow Nikolas , Kirschbaum Andreas
Published: January 2017

Background Our pilot study describes our initial experience to do a laser resection of lung metastases under video-assisted thoracoscopic control via a minithoracotomy. With this approach, if needed, mediastinal lymphadenectomy is also possible.

Methods In this study, 15 patients (11 men and 4 women, mean age: 60 years) with resectable lung metastases of different solid primary tumors (colorectal cancer in seven patients, melanoma in three patients, renal cell carcinoma in two patients, and one each with oropharyngeal cancer, breast cancer, and seminoma) were included. An anterior minithoracotomy incision (approximately 5–7 cm length) was created in the fifth intercostal space and a soft tissue retractor (Alexis Protector; Applied Medical) was positioned. Two additional working ports were inserted. The entire lung was palpated via the minithoracotomy. All detected lung metastases were removed under thoracoscopic control. Nonanatomic resections were performed using a diode-pumped neodymium-doped yttrium aluminium garnet laser (LIMAX120; KLS Martin GmbH & Co KG) with a laser power of 80 W in a noncontact modus. Deeper parenchymal lesions were sutured.

Results A total of 29 lung metastases up to 30 mm in size were resected and all metastases diagnosed on preoperative imaging were detected. All diagnosed lung metastases were completely resected (R0). The median operation time was 102 (range: 85–120) minutes. Median blood loss was 47.6 mL and no postoperative complications occurred. Neither local recurrences nor new lung metastases were observed within 6 months after the procedures.

Conclusion Video-assisted laser resection of lung metastases is safe, effective, and fulfills the requirements of modern lung metastases surgery.
Bundesweite Befragung zur Versorgungssituation und -hindernissen von Kindern psychisch kranker Eltern aus Sicht der Erwachsenenpsychiatrie
Authors: Wlodarczyk Olga , Metzner Franka , Pawils Silke
Published: January 2017

Ziel der Studie Versorgungssituation und -hindernisse bei der Unterstützung von Kindern psychisch erkrankter Eltern aus Sicht der Erwachsenenpsychiatrie.

Methode Deutschlandweite Querschnittsbefragung von 441 Ärzten und Psychologen aus 239 Fachkrankenhäusern.

Ergebnisse Hindernisse waren hohe Arbeitsbelastung, knappe Ressourcen, patientenfokussierte Behandlung, fehlende Fachkenntnisse, unzureichendes Problembewusstsein.

Schlussfolgerung Mehr Ressourcen, Weiterbildungen, klare Zuständigkeitserklärungen und Koordination sind Voraussetzungen für die Implementierung familienfokussierter Angebote.
Unterschiede in Kognition, Depressivität und gesundheitsbezogener Lebensqualität zwischen Versicherten der GKV und PKV im hohen Alter
Authors: Bock Jens-Oliver , Hajek André , Lühmann Dagmar , Ernst Annette , Mamone Silke , Wiese Birgitt , Weyerer Siegfried , Werle Jochen , Pentzek Michael , Fuchs Angela , Stein Janine , Luck Tobias , Bickel Horst , Weeg Dagmar , Wagner Michael , Scherer Martin , Riedel-Heller Steffi , Maier Wolfgang , König Hans-Helmut ,   für die AgeCoDe & AgeQualiDe Study Group
Published: January 2017

Ziel der Studie Analyse möglicher Unterschiede in Kognition, depressiven Symptomen und gesundheitsbezogener Lebensqualität zwischen GKV- und PKV-Versicherten im hohen Alter.

Methodik N = 854 (nGKV = 773, nPKV = 81) Hausarztpatienten (Alter ≥ 85 Jahre) wurden mittels Global Deterioration Scale, Geriatric Depression Scale und EQ-VAS untersucht.

Ergebnisse Leichte deskriptive Unterschiede in den betrachteten Maßen erwiesen sich in multiplen Regressionsanalysen nicht als statistisch signifikant.

Schlussfolgerung Zwischen GKV- und PKV-Versicherten bestehen keine Unterschiede in den untersuchten Maßen.
What's Cooking, Man? Masculinity in European Cooking Shows after The Naked Chef
Authors: Leer Jonatan
Published: January 2017

The cooking show The Naked Chef (1999–2001) with Jamie Oliver has often been highlighted as an example of the cooking show genre's potential for reformulating masculine identity through cooking. Through a series of close readings of a selection of cooking shows from France, the UK and Denmark post-The Naked Chef and through a dialogue with other works on the subject, this article will attempt to identify the tendencies in the constructions and negotiations of masculinity in the cooking show genre following The Naked Chef and to understand these in relation to a revision of masculine identity in contemporary culture. The article is informed by poststructural gender theory and understands ‘doing food’ and ‘doing masculinity’ as two mutually constituting practices. The analyses identify four new tendencies in the construction of masculinity in cooking shows at the beginning of the twenty-first century: 1) rechefisation, 2) the TV chef as a moral entrepreneur, 3) the TV chef and the revitalisation of the national myth and 4) cooking as masculine escapism. The article concludes that the innovation of the masculine identity that was launched in The Naked Chef has not continued; rather, the genre has become a platform for the revitalisation of traditional masculinity discourses.
Biting the Hand that Feeds: Australian Cuisine and Aboriginal Sovereignty in the Great Sandy Strait
Authors: Woodcock Shannon
Published: January 2017

Wilhelmina (Mina) Rawson (1851–1933) is lauded in both academic and popular circles as the author of the first uniquely Australian cookbooks, which she wrote between 1876 and 1895. Rawson was a prolific writer and stressed that she was the first white woman settler at Boonooroo in the colony of Queensland, where she was ‘beholden to the blacks’ to show her what to eat (Rawson, 1895, p. 54). Rawson's cookbooks famously codified how to use Australian non-human animals, including wallaby, parrot and goanna, as meat, and her published memories of this time detailed the context in which she implemented and refined these recipes. Rawson organised and policed racialised frontier space as a white woman, claiming British sovereignty over Butchulla country in order to profit from and teach other settlers to profit from the coastal land and waterways. This paper draws on ecofeminist and postcolonial theory and works to explore how Rawson organised food production to exercise violent colonial claims to sovereignty as a white woman, explicitly advising other settlers to do the same.
Fabrication of double barrier structures in single layer c-Si–QDs/a-SiOx films for realization of energy selective contacts for hot carrier solar cells
Authors: Kar Debjit , Das Debajyoti
Published: January 2017

Thin films of c-Si–QDs embedded in an a-SiOx dielectric matrix forming arrays of double barrier structures have been fabricated by reactive rf-magnetron sputtering at ∼400 °C, without post-deposition annealing. The formation of larger size c-Si–QDs of reduced number density in homogeneous distribution within a less oxygenated a-SiOx matrix at higher plasma pressure introduces systematic widening of the average periodic distance between the adjacent ‘c-Si–QDs in a-SiOx’, as obtained by X-ray reflectivity and transmission electron microscopy studies. A wave-like pattern in the J-E characteristics identifies the formation of periodic double-barrier structures along the path of the movement of charge carriers across the QDs and that those are originated by the a-SiOx dielectric matrix around the c-Si–QDs. A finite distribution of the size of c-Si–QDs introduces a broadening of the current density peak and simultaneously originates the negative differential resistance-like characteristics, which have suitable applications in the energy selective contacts that act as energy filters for hot carrier solar cells. A simple yet effective process technology has been demonstrated. Further initiative on tuning the energy selectivity by reducing the size and narrowing the size-distribution of Si–QDs can emerge superior energy selective contacts for hot carrier solar cells, paving ground for accomplishing all-Si solar cells.
Electric control of magnetism in low-dimensional magnets on ferroelectric surfaces
Authors: Odkhuu Dorj , Tsevelmaa Tumurbaatar , Rhim S. H. , Hong Soon Cheol , Sangaa Deleg
Published: January 2017

Employing first-principles electronic structure calculations, we have studied the electric field controls of magnetism and magnetic anisotropy energy (MAE) of the Fe adatoms on ferroelectric BaTiO3 and PbTiO3 surfaces. Remarkably, those effects exhibit dependence of the level of coverage as well as adsorption site of Fe atoms. While the magnitude of MAE is shown tunable by ferroelectric polarization in the full coverage of Fe monolayer, the direction of magnetization undergoes a transition from perpendicular to in-plane for the half or lower coverages. This magnetization reorientation is mainly ascribed to the site-dependent Fe d–O p hybridization, as a consequence of the formation of FeTiO2 layer at the surface.
Suitability of the double Langevin function for description of anhysteretic magnetization curves in NO and GO electrical steel grades
Authors: Steentjes Simon , Petrun Martin , Glehn Gregor , Dolinar Drago , Hameyer Kay
Published: January 2017

This paper compares the match obtained using the classical Langevin function, the tanh function as well as a recently by the authors proposed double Langevin function with the measured anhysteretic magnetization curve of three different non-oriented electrical steel grades and one grain-oriented grade. Two standard non-oriented grades and a high-silicon grade (Si content of 6.5%) made by CVD are analyzed. An excellent match is obtained using the double Langevin function, whereas the classical solutions are less appropriate. Thereby, problems such as those due to propagation of approximation errors observed in hysteresis modeling can be bypassed.
Modeling temperature dependent exchange bias in systems with magnetoelectric chromia
Authors: Ahmed Rizvi , Victora R. H.
Published: January 2017

Exchange bias in a magnetoelectric Cr2O3/ferromagnet system at finite temperature, based on the formation of a domain wall in Cr2O3, has been investigated using Monte Carlo simulation. It has been shown that the calculation of the exchange bias based on domain wall formation yields a more realistic value than that calculated using interfacial exchange coupling between Cr2O3 and the adjacent ferromagnet. Possible shortcoming of the magnetoelectric effect in setting the switchable exchange bias in the low temperature regime has also been demonstrated based on an energy threshold requirement. Specifically, it has been found that the magnetoelectric effect becomes intrinsically less effective in switching the exchange bias at low temperature, thus making the applicability of the system limited to only a certain temperature range.
Soft electroactive actuators and hard ratchet-wheels enable unidirectional locomotion of hybrid machine
Authors: Sun Wenjie , Liu Fan , Ma Ziqi , Li Chenghai , Zhou Jinxiong
Published: January 2017

Combining synergistically the muscle-like actuation of soft materials and load-carrying and locomotive capability of hard mechanical components results in hybrid soft machines that can exhibit specific functions. Here, we describe the design, fabrication, modeling and experiment of a hybrid soft machine enabled by marrying unidirectionally actuated dielectric elastomer (DE) membrane-spring system and ratchet wheels. Subjected to an applied voltage 8.2 kV at ramping velocity 820 V/s, the hybrid machine prototype exhibits monotonic uniaxial locomotion with an averaged velocity 0.5mm/s. The underlying physics and working mechanisms of the soft machine are verified and elucidated by finite element simulation.