bluuebunny/crossref_metadata_2025 huggingface dataset:
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PENGGUNAAN STYROFOM SEBAGAI KEMASAN MAKANAN OLEH PENJUAL MAKANAN DI KECAMATAN POLEWALI
Authors: Abdullah Astuti , Nengsi Sri , Wahyuni Annisa
Published: December 2022

Styrofoam inilah kemasan makanan yang biasa dipakai oleh pedagang makanan, padahal styrofoam mengandung styrene yang dapat menyebabkan kanker. Semakin panas makanan yang disimpan dalam styrofoam, semakin cepat zat beracun dari styrofoam masuk ke dalam makanan. Styrofoam juga berdampak negatif terhadap lingkungan karena sulit didaur ulang.Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang berhubungan dengan penggunaan styrofoam sebagai kemasan makanan oleh pedagang makanan. Penelitian ini menggunakan metode survei analitik dengan pendekatan cross sectional. Sampel sebanyak 96 dengan menggunakan total sampling. Analisis data adalah analisis univariat dan bivariat dengan uji statistik chi-square.Hasil analisis chi-square menunjukkan tidak ada hubungan antara pendidikan  dan penggunaan styrofoam dengan p-value 0,078, tidak ada hubungan antara lama penjualan dengan penggunaan styrofoam dengan p-value 0,853. , ada hubungan antara pengetahuan dan penggunaan styrofoam dengan p-value 0,000, ada hubungan antara sikap dan penggunaan styrofoam dengan p-value 0,000, ada hubungan antara ketersediaan wadah dengan penggunaan Styrofoam di pedagang makanan dengan p-value 0,029. Diusulkan agar penjual makanan untuk ganti kemasan styrofoam dengan kemasan yang lebih aman.
PENGARUH PEMBERIAN DOSIS PUPUK SANTAMIKRO DAN INTERVAL WAKTU YANG BERBEDA TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN TERUNG UNGU (Solanum melongena.L)
Authors: Buddin Saha , Karim Harli A , Jamal Abdul
Published: December 2022

Penelitian ini dilaksanakan di Kecamatan Tappalang Kabupaten Mamuju Propinsi Sulawesi Barat, dan dilksanakan pada bulan Juli sampai September 2019. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian dosis pupuk mikro (santamikro) dan interval waktu yang berbeda terhadap pertumbuhan dan produksi tanaman terung ungu (Solanummelongena L). Penelitian ini menggunakan Rancangan Acak Kelompok yang terdiri dari rancangan Acak Kelompok (RAK) dengan analisis faktorial 3 x 2 yang terdiri atas 3 ulangan. Faktor perlakuan dalam penelitian ini terdiri dari dua (2) faktor, yaitu Faktor I, adalah pemberian Dosis pupuk mikro (santamikro) Terdiri 3 taraf yaitu 1,5 gram/20 liter air, 2,5 gram/20 liter air  dan 3,5 gram/20 liter air. Sedangkan faktor kedua  adalah Interval waktu pemberian pupuk santamikro  yang terdiri dari 2 taraf, yaitu Pemberian pupuk 2 minggu sekali  danPemberian pupuk 3 minggu sekali. Hasil penelitian menunjukkan bahwa Terdapat interaksi yang sangat nyata antara pemberian dosis pupuk santamikro 3,5 gram/20 liter air dan interval waktu pemberian pupuk santamikro 3 minggu sekali terhadap parameter berat buah terung per tanaman. Pemberian dosis pupuk santamikro berpengaruh sangat nyata terhadap parameter tinggi tanaman umur 15, 30 45 HST, Jumlah daun umur 30, 45 HST, diameter buah, Jumlah buah per tanaman berat buah pertanaman dan berpengaruh nyata terhadap panjang buah. Perlakuan dosis pupuk santamikro 3,5 gram /20 liter air pada umumnya memberikan pertumbuhan dan hasil tanaman terung yang terbaik.KataKunci : Terung, Santamikro, interval waktu, dan produksi.
NILAI RELIGI KUMPULAN PUISI SAJAK LANGIT KARYA ALVIN SHUL VATRICK DKK DENGAN TEORI STRUKTURALISME GENETIK
Authors: Azis Gusman , Sahabuddin Chuduriah , Muttalib Abdul
Published: December 2022

Karya sastra merupakan hasil cipta sastra yang mengungkapkan masalah tentang kemanusiaan. Perumusan masalah pada penelitian tersebut bagaimanakah nilai religi puisi berjudul Sajak Langit, Hilang, Kejora, Selembar Cahaya, Ada yang Belum Sempat Kuceritakan, Izinkan, Denging Itu Isyarat Ada Hidup, Semesta Kabut, Memuja Semesta dan Yang Membentang dalam kumpulan puisi Sajak Langit karya Alvin Shul Vatrick dkk. Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan nilai religi puisi karya Alvin Shul Vatrick dkk. Dalam penelitian ini memilih puisi-puisi karya Alvin Shul Vatrick dkk yang diasumsikan memiliki nilai-nilai religi. Penelitian tersebut merupakan kepustakaan dengan fokus penelitian pada nilai religi. Teknik pengumpulan data pada skripsi ini adalah metode kualitatif dengan teknik pustaka, simak dan catat dengan analisis data menggunakan analisis konten. Dalam hal ini, peneliti akan mengungkapkan nilai religi yang terkandung dalam puisi-puisi Alvin Shul Vatrick dkk. Hasil penelitian ini dapat disimpulkan bahwa puisi yang berjudul Sajak Langit, Hilang, Kejora, Selembar Cahaya, Ada yang Belum Sempat Kuceritakan, Izinkan, Denging Itu Isyarat Ada Hidup, Semesta Kabut, Memuja Semesta dan Yang Membentang dalam kumpulan puisi Sajak Langit karya Alvin Shul Vatrick dkk memiliki tiga aspek nilai religi, yaitu nilai religi manusia dengan manusia, manusia dengan alam dan manusia dengan Tuhan.
In Practice: Operationalizing Life Cycle Assessment for Design Teams
Authors:   The Miller Hull Partnership, Ianchanko Alex , Jones Brie ,   The Miller Hull Partnership
Published: December 2022

In the context of ongoing anthropogenic climate change, the building sector bears a significant responsibility to curtail greenhouse gas emissions. To quantify and reduce their environmental impact, building industry professionals are rapidly adopting life cycle assessment (LCA) tools. However, before LCA is adopted in practice as a routine part of the design process, three gaps must be addressed – the knowledge gap of understanding upstream emissions from other economic sectors, the communication gap of effectively conveying LCA study results, and the method gap of matching LCA tools to design team needs. This paper presents a meta-analysis of forty-nine recent LCA studies completed by the Miller Hull Partnership in pursuit of carbon-sequestering design, and describes lessons learned in traversing the knowledge, communication, and method gaps in order to embed LCA in the design process. Our experience demonstrates three possible strategies – the knowledge gap can be closed when practitioners engage with professionals in adjacent sectors in interdisciplinary research; the communication gap can be closed when design teams leverage replicable data collection and visualization tools; and the method gap can be addressed by deliberately framing LCA studies as iterative hotspot analyses rather than retroactive, static performance studies.
The Footprint of Tight: Hinterlands, Landscape and Dense Cities
Authors:   RMIT University, Doyle John , Christ Graham ,   RMIT University
Published: December 2022

The Supertight refers to the small, intense, robust and hyper-condensed spaces that emerge as a by-product of extreme levels of urban density. These ideas were explored through a site-specific architectural installation and curated exhibition that was held in Melbourne in 2019 and drew on contributions from practitioners throughout Asia to explore the role of design in negotiating and expressing density in urban environments. The project explored the term ‘Tight’ as a positive and more nuanced approached to thinking about urban density. If the Supertight is focused on cities, its consequence is equally on the landscapes that support cities. While we as architects focus on the object of density, the centre of cities – their organisation, occupation and formal characteristics, we often overlook the vast hinterland that supports dense urban cores. Cities such as Singapore and Hong Kong, which were explored heavily through the exhibition and are in many ways models of the physical and social management of extreme density, are equally exemplars of cities that rely heavily on supply chains that stretch well beyond their borders. This paper will build upon discussions emerging from the Supertight exhibition and will critically reflect upon and document the relationship between dense urban cores and the broader networks that support their existence. While urban density and compact cities are generally understood to be more sustainable than sprawl, to what extent does the close settlement of cities result in an expansion of terrain and resources to support them? Do dense cities require more to enable their existence, and how does behaviour and patterns of consumption impact that potential for density to be sustainable? The paper will explore how productive landscapes that support dense cities be absorbed within dense urban cores, and what would need to shift to enable this.
Advancing Construction Through the Buildings Workforce
Authors:   National Renewable Energy Laboratory (NREL), Truitt Sarah , Salzman Madeline ,   U.S. Department of Energy Building Technologies Office (BTO)
Published: December 2022

Buildings are America’s energy hogs, consuming more than 70% of all electricity and more than 50% of all natural gas produced across the country.1 Achieving a clean energy future requires us to reinvent how buildings manage energy resources and how consumers demand it. The U.S. Department of Energy (DOE) is investing in a range of technological advancements that are paving the way to a future in which buildings are no longer simply energy consumers, but rather are part of an integrated system that helps manage energy resources in a way that supports the electricity grid. This paradigm shift presents an opportunity to increase the efficiency of the built environment but will only be realized if we build a knowledgeable workforce to design, construct, and operate these high-performance buildings2 in step with the rate of technological advancement.
Post-Oil Environments: Responsive Design Strategies for Coastal City-Landscapes of Oil
Authors:   University of Texas at Arlington, Jenewein Oswald
Published: December 2022

This paper summarizes parts of an interdisciplinary research and design project on climate adaptation strategies on the scale of architecture and the city within the case-study territory of Corpus Christi Bay in South Texas. In particular, this paper assesses the challenges of the emerging process of re-industrialization along the Texas Coast, highlighting significant impacts of industrial growth on the city landscape of Downtown Corpus Christi, which is located directly adjacent to the industrial oil port. A proposed masterplan is shown in this paper to demonstrate how responsive design strategies may benefit post-oil city-landscapes in the age of anthropogenic climate change. The emphasis is storm-water and flood mitigation, walkability, alternative transportation, and urban place-making in response to community input related to the United Nations Sustainable Development Goals (SDGs) and the AIA Framework for Designing for Equitable Communities. Methodologically, this project builds upon a mixed-methods approach. It includes qualitative and quantitative data gathered through Participatory Action Research, a successful tool to connect the research team and students to local communities, stakeholders, and constituents. The paper suggests that this era of re-industrialization needs to be seen as a transformative process that enables the aging city landscape to adapt to both changing ecological conditions and the time after this late oil boom. Urban identity, socio-economic diversity, and healthy conditions for urban ecosystems are essential parameters to inform the development of comprehensive strategies for the built environment. The responsive design strategies shown in this paper pro- pose the implementation of an infrastructural landscape addressing these challenges. The central element of the master plan is a canal that serves multiple purposes, including disaster preparation and response infrastructure, stormwater management, and alternative transportation for inner-city and city-to-city connections, has been developed to adapt Downtown Corpus Christi to the projected ecological changes.
Mapping the Built Environment Process (BEP) Ecosystem via a Data to Knowledge Framework
Authors:   Yale Center for Ecosystems in Architecture, Yale University, Keema Naomi , Dyson Anna ,   Yale Center for Ecosystems in Architecture, Yale University,   Yale Center for Ecosystems in Architecture, Yale University, Etman Mohamed Aly
Published: December 2022

Transitioning to a future of low-carbon built environments requires the design of multi-beneficial design strategies that take a whole building life cycle and systems-thinking approach. Such an approach has the potential to enable multi-stakeholder engagement and cross-industry collaboration which are current siloed in the Built Environment Process (BEP). The BEP involves energy, material and information flows at each of its phases from the initial extraction of raw materials to the final deconstruction of a building. Technology and big data have a role to play in establishing collaborative networks with efficient construction practices which track material, energy and information flows across the building life cycle. This paper attempts to map the BEP through a new data-to-knowledge framework named SEVA (Socio-Ecological Visual Analytics), which has been designed to link heterogeneous data. It describes the methodology used to map the BEP in SEVA. This involves the deployment of semantic web ontologies to generate a knowledge graph of the BEP; virtually connecting each phase and its associated stakeholders, thereby, conceivably acting as an overview tool for the BEP. As climate pressures increase and material scarcity is imminent, innovation in eco-systems thinking and data-to-knowledge frameworks will be critical towards ensuring built environments embrace a socio-ecological future.
Faktor yang Berhubungan dengan Keluhan Gangguan Pendengaran pada Tenaga Kerja Pembangunan Dermaga di PT. Pelindo IV Makassar New Port
Authors: Adha Nurul , Mulyadi Mulyadi , Rivai Abdur , Farida Farida
Published: December 2022

Kemajuan ilmu pengetahuan dan teknologi telah membawa industri dan mekanisme tumbuh berkembang dalam rangka mewujudkan masyarakat industri yang maju dan mandiri. Salah satu bahaya yang umum dan sering ditemui di industri adalah bahaya kebisingan. Pemajanan kebisingan yang melebihi batas ambang yang ditentukan merupakan risiko pada fungsi pendengaran manusia dan juga secara langsung dapat menurunkan produktivitas kerja pada pekerja. Setiap pekerja yang terpajan kebisingan mempunyai risiko untuk mengalami gangguan pendengaran. Penelitian ini merupakan penelitian analitik dengan rancangan penelitian secara cross sectional, jumlah sampel sebanyak 80 dengan metode pengambilan sampel menggunakan purposive sampling. analisis data dengan menggunakan uji statistik pearson correlation. Hasil penelitian menunjukkan bahwa dari empat variabel yang diteliti terdapat satu variabel yang tidak memiliki hubungan yang signifikan yaitu masa kerja (P=0,097) sedangkan untuk variabel intensitas kebisingan(P=0,038) lama kerja (P=0,037) dan pemakaian Alat Pelindung Telinga (P=0,027) memiliki hubungan yang signifikan dengan keluhan gangguan pendengaran pada tenaga kerja pembangunan dermaga. Maka simpulan dari penelitian ini adalah secara statistik terdapat hubungan yang signifikan antara intensitas kebisingan, lama kerja dan pemakaian alat pelindung telinga (APT) dengan keluhan gangguan pendengaran pada tenaga kerja pembangunan dermaga di PT.PP Pelindo IV Makassar New Port, sedangkan masa kerja tidak ada hubungan signifikan dengan keluhan gangguan pendengaran pada tenaga kerja pembangunan dermaga di PT.PP Pelindo IV Makassar New Port. Disarankan bahwa  kepada tenaga kerja di PT. Pelindo IV Makassar New Port, agar memakai alat pelindung telinga dengan baik dan benar serta konsisten pada saat bekerja guna mengurangi risiko terjadinya keluhan gangguan pendengaran.
Penyuluhan Pengaruh Prenatal Yoga terhadap Tingkat Kecemasan pada Ibu Hamil Primigravida
Authors: Farasari Poppy , Widyawati Evita , Oktaviana Friska , Farida Farida , Yitno Yitno
Published: December 2022

Kecemasan dalam masa kehamilan merupakan hal yang sangat merugikan teruntuk ibu hamil, dikarenakan bisa mempengaruhi janin yang berada dikandungngan. Sifat-sifat mudah menangis, tersinggung serta mudah cemas bisa mengakibatkan kelahiran yang premature dan mengakibatkan terjadinya hambatan pada intelektual, perkembangan motorik, perkembangan bicara dan perkembangan emosi. Prenatal yoga bermanfaat untuk menurunkan tingkat kecemasan. Penyuluhan ini diberikan kepada 43 peserta yang dilakukan di Balaidesa Desa Sukodono Tulungagung. Metode Pengabdian Masyarakat ini dilakukan dengan memberikan penyuluhan mengenai informasi terkait pengaruh prenatal yoga terhadap tingkat kecemasan pada ibu hamil dengan metode pada tahap awal, materi diberikan tentang definisi, manfaat, dan melakukan gerakan prenatal yoga bersama. Hasil pada kegiatan Pengabdian Kepada Masyarakat tentang pengaruh prenatal yoga terhadap ibu hamil primigravida ini didapatkan bahwa peserta menyimak, antusis dan mampu memahami materi yang disampaikan oleh pelaksana kegiatan penyuluhan.
THEMATIC LEARNING AND ITS APPLICATION IN THE LEARNING PROCESS
Authors: Zulfianita Eka
Published: December 2022

Cooperative learning arises from the concept that learners will more easily find and understand complex concepts if they discuss them with their friends. Students regularly work in groups to help each other solve complex problems. This type of research is a case study. This conclusion research can be that the planned implementation of cooperative learning model type STAD includes; 1) the teacher prepares the program of the semester and syllabus compiled together a team of the KKG at the beginning of the semester. 2) preparing lesson plans. Making model cooperative type STAD includes 1) The Beginning, 2) the Core Activities, and 3) The End of the Activity. At the same time, the impact of the STAD Cooperative learning model on the learning theme in improving students' learning outcomes has a positive and negative effect.
Pembelajaran kooperatif muncul dari konsep bahwa peserta didik akan lebih mudah menemukan dan memahami konsep yang sulit jika mereka saling berdiskusi dengan temannya. Peserta didik secara rutin bekerja dalam kelompok untuk saling membantu memecahkan masalah-masalah yang kompleks. Jenis penelitian ini adalah  kulaitatif dengan pendekatan studi kasus. Dari hasil penelitian ini dapat dismpulkan bahwa perencanaan penerapan model pembelajaran kooperatif tipe STAD diantaranya; 1) Guru menyiapkan program semester dan silabus yang disusun bersama tim KKG pada awal semester. 2) Menyusun RPP. Penerapan model kooperatif tipe STAD dengan meliputi: 1) Kegiatan Awal  2) Kegiatan Inti  3) Kegiatan Akhir. Sedangkan dampak penerapan model pembelajaran Kooperatif Tipe STAD pada pembelajaraan tematik dalam meningkatkan hasil belajar peserta didik memiliki dampak positif dan negatif.
Liquid thermoelectric conversion devices composed of several organic solvents
Authors: Wake Akihiro , Inoue Dai , Moritomo Yutaka
Published: December 2022

We evaluated the performances of liquid thermoelectric conversion devices (LTEs) composed of nine organic solvents containing an Fe2+/Fe3+ redox pair against the electrolyte concentration (m). In protic solvents, i.e. methanol (Me), ethanol (Et), 1-propanol (Pr), and ethylene glycol (EG), the electrochemical Seebeck coefficient (α = d
V/d
T, where V and T are the electrode potential and temperature, respectively) increases with m in the small m region. Based on the ultraviolet—visible absorption spectroscopy, we interpreted the enhancement of α in terms of the OH− and/or H2O coordination to Fe3+, which was introduced by the crystal water of the solute. At a temperature difference (ΔT) of 30 K, the maximum value of the power factor of the Me LTE reaches 11.5 μW K−2m.
La mujer en las películas de Disney. una propuesta pedagógica
Authors: ROS-GARRIDO Alicia , GARCÍA-RUBIO Juan
Published: December 2022

Este artículo muestra una mirada y un examen necesario acerca de las películas de Disney y del papel de la mujer en ellas, desde las tradicionalmente famosas con princesas a las más recientes protagonizadas por mujeres con inquietudes e iniciativa, que no necesitan un príncipe en sus vidas y en las que ellas mismas deciden su destino. En concreto, se ofrece una propuesta didáctica que tiene como pretensión la comprensión, el análisis, la reflexión y el diálogo acerca de la película de Maléfica, proporcionando una herramienta que posibilita indagar en una de las cintas cinematográficas de Disney que embelesan a los niños y a las niñas de la sociedad, la futura ciudadanía. Sin darnos cuenta, o tal vez con total premeditación, se sigue produciendo y reproduciendo una sociedad patriarcal que a través de la educación se ha de conseguir transformar.
ASSIGNMENTS OF THE VETERINARY MEDICINE SPECIALISTS TO COMPLY WITH THE PROVISIONS OF THE PROCEDURE FOR THE USE OF ANTIMICROBIAL VETERINARY MEDICINES
Authors: Kosenko Yu. M. , Ostapiv N. V. , Zaruma L. E.
Published: December 2022

The problem of tackling antimicrobial resistance to antimicrobial agents on a global scale is of great importance over the last few years. Governments of many countries and professional organizations developed a lot of legislative orders, requirements, and guidelines concerning this problem based on a ‘One-Health’ approach. Surveillance of the development of acquired antimicrobial resistance and monitoring the circulation of antimicrobials in veterinary practice and medicine is one of the steps to address this problem.

The main goal of this study was the assignment of the veterinary medicine specialists' tasks in the implementation of the “Procedure for the use of antimicrobial veterinary medicinal products”, 2021. (hereinafter “Procedure”).

National Agency of veterinary medicinal products and feed additives (hereinafter Agency) during the last six years is collecting annual sales data on antimicrobial veterinary medicinal products in food-producing and domestic animals in accordance with Chapter 6.9. of the Terrestrial Animal Health Code, 2018. The Agency must inform all the stakeholders about the problems revealed in this study because they are of great importance for the prudent use of antimicrobial agents and implementation of the requirements of the “Procedure”.

Results of the antimicrobials sales reports monitoring in 2020 revealed an increase in the parts of macrolides (14%) and fluoroquinolones (15,2%), which are classified as critical antimicrobials of categories C and B, respectively According to the European Center for Disease Prevention and Control, the European Food Safety Authority and the European Medicines Agency (ECDC / EFSA / EMA, 2021), a statistically significant positive relationship was found between the consumption of fluoroquinolones to Salmonella spp., іn poultry and the resistance of isolated from poultry Salmonella spp. to fluoroquinolones and a significant association with Campylobacter jejuni resistance in humans. Therefore, the use of these categories of antimicrobials should be substantiated by veterinarians.

Monitoring data do not allow us to state that all antimicrobials sold have been used, but the increase in their share is a matter of concern taking into account the requirements set out in the "Procedure for the use of antimicrobial medicinal products". The article formulates the tasks to be performed by veterinary specialists to implement the requirements for the use of antimicrobial veterinary medicinal products set out in the "Procedure", approved by the order of the Ministry of Economy of Ukraine № 1177-21 of 30.12.2021.
EFFECIENCY AND SAFETY OF THE VETERINARY MEDICINAL PRODUCT VETASEPTOL IN THE TREATMENT OF PIGS SUFFERING FROM ACUTE RESPIRATORY DISEASE OF BACTERIAL ETIOLOGY
Authors: Lisova N. , Shkodyak N. , Sobodosh O. , Zhyla M. , Maksymovych O. , Myhalyuk O. , Stetsko T. , Ostrovska L.
Published: December 2022

The article presents the results of clinical trials on pigs of the veterinary medicinal product Vetaseptol (powder for oral use), manufactured by “Ukrvetrompostach LLC”. The drug was used orally with feed for the treatment of acute respiratory infection in 2-month-old piglets in the dosage recommended by the manufacturer. Before the experiment, microbiological studies were conducted on selection and identification of microorganisms, pathogens of respiratory infection in pigs, and establishing of their sensitivity to the active substances of the drug (oxytetracycline and erythromycin). During the experiment, constant observation of the clinical condition and physiological parameters of the body of the experimental animals were performed. Evaluation of hematological and biochemical indicators was carried out according to recognized methods. The therapeutic efficiency was compared with the data obtained before the treatment and after using the comparator drug. On the basis of obtained data and their statistical analysis, conclusions about the effeciency of Vetaseptol in the treatment of pigs, suffering from streptococcosis, and its effect on their organism were made.

According to the evaluation of the animal’s clinical condition and the results of laboratory tests obtained, it was established that the tolerability of the studied drug for the treatment of respiratory infection of young pigs was good. During the experimental period and two weeks after the use of the drugs, no side effects were detected and no changes in the behavior of the piglets were observed. The therapeutic effectiveness of the test drug was 100%, and the recovery time was almost 5 days. A comparative analysis of piglet’s hematological indicators showed a reliable decrease of monocytes number in the animal’s leukogram after antibiotic therapy. The normalization of the piglet’s leukogram indicated the termination of inflammatory processes and the improvement of the physiological state of animals. The serum biochemical profile of experimental animals hasn’t changed significantly. Laboratory studies did not reveal hemo- and hepatotoxic effects of the antimicrobial drug.
DEVELOPMENT OF METHODS FOR QUANTITATIVE DETERMINATION OF MEBENDAZOLE AND ITS METABOLITES IN BIOLOGICAL TISSUES USING HPLC/ DAD
Authors: Melikyan S. , Biront N. , Pazderska O. , Mys’ko G. , Yanovych D.
Published: December 2022

This manuscript presents the results of developed method is intended for clinical and pharmaceutical studies of veterinary drugs based on the active substances mebendazole and its main metabolites: mebendazole amin and mebendazole hydroxide in sheep muscles and liver. Tissue samples were made alkaline with sodium carbonate, extracted twice with acetonitrile and degreased with hexane. The extracts are further purified using a series of liquid-liquid extraction and solid phase extraction. After concentration and drying, the dry residue was recovered in the mobile phase. Separation was performed on an inverted phase Kinetex EVO С18 column using acetonitrile and phosphate buffer as the mobile phase. The gradient mode of eluents was used during 10 min at a flow rate of 1,5 ml/min. The peak retention time of a mebendazole is 3,4 min, mebendazole hydroxide is 4,1 min, and the retention time of mebendazole amin peak is 6,1 min. The specificity of the analytical method was checked by comparing the chromatographic separation of a sample of muscle tissue and liver enriched with a standard solution of a mixture of mebendazole and its main metabolites at the level of MDR and a sample of muscle tissue and liver placebo. The procedure of sample preparation of fortified tissues to construct calibration graphs is described in the manuscript. The validation parameters of the method “recovery” and “coefficient of variation” were considered in accordance with the criteria of Council Directive 2002/657/EC. The mean recovery from fortified muscle tissue in the range of 40.0-60.0 μg/kg mebendazole and its metabolites was 98 %. The average extraction of the studied analytes from the loaded liver in the range of 200.0 - 600.0 μg/kg was 100 %. The average coefficient of variation for each compound was ≤ 10 %.

The method is linear in the concentration range of 5 – 100.0 μg/kg of each analyte in muscles and 50,0 – 800,0 μg/kg in liver. The results obtained in the study of the linearity of this technique were used to estimate the correctness and convergence. The accuracy of the measurements was evaluated by examining the known amounts of analytes added to the control muscle tissue. Recovery data are acceptable because they are within ± 10% of the target value. The method has sufficient convergence (accuracy). The evaluation of the intermediate accuracy of mebendazole and its main metabolites was assessed on three different days of analysis. The average CV for each compound was <10 %. Selectivity and high sensitivity are the main advantages of the developed technique. The developed HPLC/DMD method can be used to study the deficiency of mebendazole and its metabolites.
MORPHOLOGICAL INDICATORS OF BLOOD IN CATS WITH CALICIVIROSIS
Authors: Radzіkhovskyі N. , Sachuk R. , Sokulsky I. , Dyshkant О. , Tolokevich O.
Published: December 2022

In recent years, there has been a massive trend in Ukraine to keep cats, which has inevitably led to an increase in the incidence of their diseases. In the general pathology of cats, viral diseases occupy a leading place, and of particular concern is calicivirosis, which is caused by a virus capable of high mutation rates and can cause atypical course with nonspecific manifestations of clinical signs. Therefore, given the urgency of this issue, the result of our research is to clarify, supplement and summarize data on hematological and biochemical parameters of blood and erythrocytopoiesis in calicivirosis in cats, because blood is a sensitive and informative indicator of the body, responds quickly to changes as exogenous. and endogenous factors. The research was conducted in veterinary clinics of Zhytomyr and Kyiv, on purebred and outbred cats (n = 18). Diagnostic studies to confirm feline calicevirus were performed using rapid tests Ag Test (FCV Ag), Quicking Biotech Co., Ltd. and ELISA and PCR for the presence of calicivirus antigen on the basis of a private veterinary laboratory LLC "Bald" in Kiev.

Comprehensive studies have shown that cats with calicivirosis (18) are characterized by changes in morphological and biochemical composition of blood. Deviations from physiological limits were found, namely erythrocytopenia P≤0.05, thrombocytosis P≤0.05, leukocytosis P≤0.05, monocytosis P≤0.01, increase in ESR P≤0.001 and lymphocytopenia P≤0.05, for biochemical ones it is a significant increase in the concentration of globulin P≤0.001, creatinine P≤0.001, urea P≤0.05 hyperenzymemia α-amylase P≤0.001, and ALT P≤0.05. As a result of experimental research of morphological indicators of blood the difficult pathogenesis of a disease with multiorgan insufficiency is established.
DOXYCYCLINE EFFICIENCY AND SAFETY IN THE TREATMENT OF ACUTE INTESTINAL INFECTIONS OF BACTERIAL ETIOLOGY IN BROILER CHICKENS
Authors: Shkodyak N. , Stetsko T. , Pyatnychko O. , Sobodosh O. , Lisova N. , Ostrovska L. , Balyan O.
Published: December 2022

Doxycycline is a bacteriostatic antibiotic from the group of tetracyclines, a semi-synthetic derivative of chloretracycline. It is a broad-spectrum antibiotic that is active in gram- positive and gram- negative bacteria, including some anaerobes. Therefore, the use of doxycycline drugs is relevant to solve the problem of treatment and control of mono- and polyinfections, which are caused by doxycycline sensitive and other antibiotics resistant to other antibiotics.

The article presents the results of clinical studies of a new veterinary drug Doxal (water-soluble powder for oral administration), production of PJSC “Technologist” (Ukraine), an active pharmaceutical ingredient of which is doxycycline, in the treatment of acute intestinal disease in broiler chickens.

A high level of therapeutic efficacy and safety of the Doxal studied drug in the treatment of chickens 25 daily age with colibacteriose-claspidiosis infection was established.

The diagnosis was made on the basis of anamnestic data, a clinical picture of the disease, the results of pathoanatomical section and bacteriological examination. Microorganisms – pathogens of infection, their level of sensitivity to doxycycline were selected and identified. Therapeutic efficiency of the tested drug was not inferior to the drug-comparison of Doxatib®, production of KRKA DD Novo-Mesto (Slovenia), similar in dosage form and the content of the active substance.

According to the results of laboratory tests, a positive effect of Doxal on the morpho-functional state of the body of chickens in the treatment of acute colibacteriosis-claspidiosis infection was revealed, which is confirmed by normalization with a high percentage of the reliability of morphological and biochemical blood indicators to the values of clinically healthy bird.

Comparative clinical studies have confirmed that Doxal drug is effective chemotherapeutic agent for the treatment of bacterial infections in chickens caused by microorganisms sensitive to doxycycline, and is analogous to Doxatib® by it’s action.
The Policy Implementation of Simplification Bureaucracy For Performance Improvement In The Ministry of Administrative And Bureaucratic Reform
Authors: Sipayung Naptalina , Sumaryadi I Nyoman , Daraba Dahyar , Lukman Sampara
Published: December 2022

The bureaucratic simplification policy is a direct direction from the President and that policy was the first policy which changed structure massively form structure to functional. Ministry of Administrative and Bureaucratic Reform as a pilot project for that policy implementation. This research aims to know The Policy Implementation of Simplification Bureaucracy For Performance Improvement in The Ministry of Administrative and Bureaucratic Reform and whats is the problems that opportunities and challenges the policy implementation of Simplification bureaucracy for Performance Improvement and what is the ideal model for Bureaucratic Simplification and then find what is the ideal models for optimize policy implementation. This research focuses on functional officers who were transferred from structural officers to functional) and locus in the Ministry of Administrative and Bureaucratic Reform. Research design uses qualitative with description approach. The object of this research is a number of 141 officer structure which transferred to functional (52 from echelon 3 and 89 echelon from 4). Data is obtained by using interview, observation and documentation study from 35 informants . Primary data that was obtained by interview and processed with analyzes on theory Policy Implementation by Edwards George III 1980, Theory and Simplification Bureaucracy with Guollart & Kelly with Development Organization Theory and for increasing performance using Cascio Theory 1992. All primary data especially from interview put in to coding with each informant as formulation regulator (Echelon I), implementor (echelon II) and target group (functional from echelon 3 and 4), but cause of the covid situation, part of officers work from home, I do less observation but do in deep interview via zoom. The result finds that the implementation policy of simplification bureaucracy has not optimize yet in accordance with the goals and objectives or has not brought significant changes especially in increasing performance. To do implementation for this policy needs another policy (lack of policy) especially for reward and punishment, performance appraisal, work mechanism) and changed culture organization (mindset and culture set).
Formation of Sharia Entrepreneurship ValuesIn Boarding Schools
Authors: Dwi Widyastuti Reni , Febriati Febriati , Afif Ali
Published: December 2022

This study intends to determine the method of developing the values of independence of the students of Mu'Inul Islam Kubu Raya Islamic boarding school. This type of research is qualitative research, with primary data sources, namely data obtained directly from the object of research, namely the Mu'Inul Islam Kubu Raya boarding school and secondary data sources in the form of articles and research reports) and interviews. Data was collected through observation, interviews and documentation. The collected data were then analyzed using descriptive analytical methods. The results showed: the Islamic boarding school method in developing the independence values of Mu'Inul Islam Kubu Raya students is based on the philosophy of gusjigang (a good boy, good character, good at reciting the Koran, good at trading) Sunan Kudus, the process is carried out using observation methods, practical methods, theoretical studies, motivation, facilitation, and exemplary. It can be seen from an Islamic economic perspective, the method for developing the values of independence of students at the Mu'Inul Islam Kubu Raya Islamic boarding school is taken from the values of Islamic teachings about entrepreneurship contained in the Koran, hadith and the life practices of the Prophet Muhammad SAW. the process is carried out using observation methods, practical methods, theoretical studies, motivation, facilitation, and exemplary. It can be seen from an Islamic economic perspective, the method for developing the values of independence of students at the Mu'Inul Islam Kubu Raya Islamic boarding school is taken from the values of Islamic teachings about entrepreneurship contained in the Koran, hadith and the life practices of the Prophet Muhammad SAW. the process is carried out using observation methods, practical methods, theoretical studies, motivation, facilitation, and exemplary
The Role of Government Policy and Stakeholder Engagement In Improving Performance of MSMEs In North Kayong Regency
Authors: Mursalin Adi , Pratiwi Windi , Dewi Rawa Ricola , Hendharsa Angga , Aisyah Aisyah
Published: December 2022

This study aims to examine the role of government policies and stakeholder involvement in improving the performance of MSMEs in North Kayong Regency. This research uses a mix method. The population in this study were MSME actors in North Kayong Regency, totaling 7,687 MSME actors. Sample selection using purposive sampling and quota sampling techniques. The data collection techniques used were interviews, questionnaires, documentary studies and literature studies. The analysis method used is multiple regression analysis using statistical software SPSS 26.0. The results showed that for the role of government policy, the funding aspect indicator had a significant value of 0.000 (p-value 0.000 <0.05). The facilities and infrastructure aspect has a significant value of 0.213 (p-value 0.213> 0.05). The business information aspect has a significant value of 0.010 (p-value 0.010 < 0.05). The partnership aspect has a significant value of 0.002, (p-value 0.002 < 0.05). The licensing aspect has a significance value of 0.008 (p-value 0.008 < 0.05). The business opportunity aspect has a significance value of 0.001 (p-value 0.001 <0.05). The trade promotion aspect has a significance value of 0.749 (p-value 0.749 > 0.05). Furthermore, for stakeholder involvement, namely financial institutions have a significance value of 0.034 (p-value 0.034 < 0.05) and business associations have a significance value of 0.110 (p-value 0.110 > 0.05)
The Effect of Economic Growth, Poverty and Wages On Tax Revenue
Authors: Puji Lestari Fibria Anggraini , Yolanda Yolanda
Published: December 2022

Taxes are a source of state revenue, economic growth conditions can have an impact on the taxation sector, besides that poverty and wage factors can also affect state tax revenues. The purpose of this study was to determine the magnitude of the effect of economic growth, poverty and wages on tax revenues. The sample used in this study was 30 provinces in Indonesia. The research method used in this research is descriptive quantitative analysis method. Using secondary data during 1991-2021 and analyzed with time series data regression. The results of the research conducted can be seen that economic growth has a positive and significant effect on tax revenue, poverty has a negative and significant effect on tax revenue, positive and significant effect on tax revenue. as well as tax revenue
Al-Ikhshid's Strategy and Leadership Style
Authors: Apipudin Apipudin
Published: December 2022

Al-Ikhshid is a leader who has various abilities and successes. The reign of al-Ikhshid was one of calm for the Ikhshidid dynasty. In solving problems, Al-Ikhshid used more peaceful means. Lobbying and negotiation techniques are mostly used by al-Ikhshid in achieving his goals. Both of these techniques apply a lot of persuasion. This paper aims to explain how lobbying and negotiation techniques are used by al-Ikhshid in his strategy and how al-Ikhshid's leadership style is. Through the secondary analysis method, this paper will discuss the strategies and leadership styles applied by al-Ikhshid to achieve and maintain his power. Al-Ikhshid used many lobbying techniques by establishing relationships with various powerful parties. In addition, he also applies negotiation techniques by making peace agreements. During his time as a leader, al-Ikhshid applied the benevolent autocratic leadership style which is one of the effective leadership styles. Lobbying and negotiation techniques as well as this benevolent autocratic leadership style are some of the things that are the keys to al-Ikhshid's success.
Covid-19 Self Isolation Management, East Sumba District
Authors: Liunokas O.BT , Sila Oktofianus , Maryati Tri
Published: December 2022

The status of a global pandemic or epidemic indicates that the spread of COVID-19 is very fast and worrying, namely Covid 19 1166 cases were recorded as of April 30, 2021, 802 cases were declared cured and 328 were treated and 36 people were declared dead. With details of cases of self-isolation at home 269 people, 32 cases treated at the Cendana Hotel and 27 cases treated at the Umbu Rara Meha Hospital, Waingapu. The purpose of the study was to conduct a field analysis in the application of management functions in Isoman (Independent Isolation) of Covid-19 patients in East Sumba Regency and to analyze the management needs of Covid-19 patient care in performing self-isolation at home. This research method is a survey study of descriptive data analyzed in a frequency table, namely the importance of implementing the management functions of coordination, control/supervision, budgeting/financing and evaluation of patients during COVID-19 self-isolation. The number of samples targeted was accidental sampling, namely samples that happened to be present during the study take place. Conclusion: East Sumba COVID-19 self-isolation patients with coordination management were 46% no coordination, 29% patients were not monitored, 37% did not receive fees and 34% were not evaluated.
Structural Model of Student Learning Motivation Advent High School In North Sulawesi Province
Authors: Koyongian Yeane , Tambingon Henny N , Oentoe Fientje J A , Lengkong Jeffry SJ
Published: December 2022

Study this aim for analyze the structural model motivation learn. Three variable exogenous that is image school, quality academic and quality service. Satisfaction student is variable mediation and motivation study student as endogenous variable. Study this using 300 respondents Adventist high school student at eight school in North Sulawesi class 11 and 12 with use method quantitative and technical SEM data analysis using Smart PLS application . Seven hypothesis influence direct and three hypothesis influence no direct . Research results this showing that image school take effect positive but no significant to satisfaction student, image school take effect positive and significant to motivation study students, satisfaction student take effect positive and significant to motivation study students, quality academic take effect positive and significant to satisfaction students, quality academic take effect positive and significant to motivation study students, quality service take effect positive and significant to satisfaction students and quality service take effect positive and significant to motivation study student. School image take effect positive but no significant to motivation study student through satisfaction student as variable mediation, quality academic take effect positive and significant to motivation study student through satisfaction student as variable mediation and motivation study student influenced in a manner positive and significant by quality service with satisfaction student as variable mediation
Foucault e a Justiça Pós-Penal
Authors: Castanho Germano , Dal Castel Mauricio
Published: December 2022

O presente texto tem por intuito resenhar criticamente o livro “Foucault e a Justiça Pós-Penal: críticas e propostas abolicionistas” de Clécio Lemos, de modo a ressaltar as contribuições foucaultianas para o abolicionismo penal. Assim, valendo-se do diálogo com autores que contribuíram para o desenvolvimento do abolicionismo penal enquanto teoria, a resenha apresenta a obra de Lemos, reafirmando a proposta do autor pelo necessário diálogo entre a criminologia e a filosofia. Objetivou-se, dessa forma, apresentar ao público a obra em debate através de uma perspectiva crítica e interdisciplinar, introduzindo o abolicionismo penal como teoria deslegitimante da pena e de suas finalidades tradicionais sob os enfoques da criminologia e da filosofia desenvolvida por Michel Foucault.
ЭКОНОМИЧЕСКАЯ СИТУАЦИЯ В РОССИЙСКОЙ ФЕДЕРАЦИИ
Authors: Юсупова Т.А. , Джанхотова П.М.
Published: December 2022

В статье рассматриваются особенности экономической ситуации в Российской Федерации. На сегодняшний день российская экономика сталкивается с серьезными проблемами, вызванными негативным влиянием цен на нефть и санкциями, введенными против России странами Запада. Российская экономика является частью мировой экономики и не имеет сегодня доступа к ее ресурсам. В современной экономической ситуации в России рассматриваются основные моменты и пути управления экономическим развитием территории. Наличие проблем в социальном развитии территории, связанных с такими внешними факторами, как окружающая среда, климат, политическая обстановка и экономическая ситуация, определили задачу поиска наилучшего пути решения возникших проблем, от развития экономической мощи страны и каждого субъекта Российской Федерации.