bluuebunny/crossref_metadata_2025 huggingface dataset:
Extremophiles and their Potentials in the Food Industries: A Review
Authors: G. E. John, , A. I. Elijah, , B. N. Effiong, , E. A. Okpo, , J. A. Lennox,
Published: January 2025

Extremophiles are microorganisms that thrive in extreme environments, such as high temperatures, high pressures, and acidic or alkaline conditions. These organisms have unique adaptations that allow them to survive in these harsh conditions, and they are of great interest to the food industry for a variety of applications. Extremophilic microorganisms produce a broad range of bioactive compounds, secondary metabolites, and value-added products such as flavors, food ingredients, and vitamins, therefore, making them widely applicable in the food and food processing industries. In food industries, one of the extremophiles, Rhodothermus marinus, which has been an excellent biocatalyst producing lipase as an enzyme, could be utilized to improve the aroma of food and add natural flavor to food. Others have emerged as a valuable resource for the food industry, offering solutions to food safety and preservation challenges, as well as opportunities for sustainable food processing. By harnessing the unique characteristics and enzymes of extremophiles, the food industry can improve product quality, develop novel fermentation processes, and enhance food safety. Extremophiles hold significant potential for use in the food industry; however, translating this potential into practical applications is fraught with several challenges. These challenges include specialized growth conditions, slow growth rate, and contamination risks. Advancing genetic, biotechnological, and engineering research will be pivotal in realizing the full potential of extremophiles. Ongoing exploration of these organisms is crucial not only for improving food production processes but also for fostering sustainability and driving innovation within the food industry.
Cultivation of Innovative Marketing Talents in Universities under the New Quality Productivity: A Review
Authors: Qiu Yingying , Lu Wenjun , Guo Xiaofang , Yen Tsaifa (TF)
Published: January 2025

Developing new quality productive forces is a practical need for China to adapt to the development of the new era, new economy, and new industries, which also puts forward higher requirements for the cultivation of innovative and entrepreneurial talents in universities under the background of the new era. The marketing major in universities keeps up with the trend of digitalization and has made significant progress in innovation and entrepreneurship education. However, there are still problems such as serious homogenization of talent cultivation, further optimization of the teaching team, and overly single practical teaching forms. This article attempts to explore the path of cultivating innovative talents in the marketing major of universities under the background of new quality productivity by searching relevant literature and combining the author's years of teaching observation and accumulation in the marketing major of universities, mainly including the following four aspects: a curriculum ideological and political education mechanism with "professional spirit" as the core, a "interdisciplinary, diversified, and strong characteristic" curriculum system, a progressive teacher capacity cultivation of "teaching, research, competition, and innovation", and international competitiveness cultivation, in order to promote the development of university education.
Determining the Main Morphometrical Traits to Describe Body Weight in Male Hampala Barb Fish (Hampala macrolepidota)
Authors: Siregar Fuja Arsita , Efizon Deni , Efawani  , Munru Maestro , Ramadhan Panji Anugrah , Suwardi Surahman , Putra Widya Pintaka Bayu
Published: January 2025

Aims: Determine the main morphometrical traits influencing body weight in male Hampala Barb (HB) fish.
Place and Duration of Study: The fish were taken from Kampar Kiri River at Mentulik Village, Kampar Regency, Riau Province. This research was conducted in February-April 2018.
Methodology: The survey method used in this research takes morphometric measurements of fish. Hampala fish is used as the object of research. The survey method is a research method that is carried out directly on the object of research without giving special treatment to the object under study. A total of 26 morphometrical traits were measured from 42 male HB fishes.
Results: Research showed that the average body weight of HB fishes was 245.24±136.54 g. Four morphometrical measurements of maximum body height, pre-dorsal length, pre-ventral fin length, and caudal pendulum height were selected as the leading four variables to predict body weight with the coefficient of determination (R2) of 0.95. Therefore, a variable of maximum body height can predict the body weight with an R2 value of 0.91.
Conclusion: The body weight of Hampala fish can be accurately predicted with morphometric measurements. The maximum body height can influence the body weight of Hampala fish with the R2 value of 0.91. Overall morphometrical measurements of maximum body height, pre-dorsal length, pre-ventral fin length, and caudal peduncle height can describe the body weight of Hampala fish with R2 = 0.95.
Photolytic Degradation of Methylene Blue: The Effect of Various Factors on Wastewater Treatment Efficiency
Authors: Appia Foffié Thiery Auguste , Kouassi Tiémélé Ghislaine Désirée , Kimou Kouakou Jocelin , Coulibaly Charlène Sandra , Meledje Jean-Claude , Ouattara Lassiné
Published: January 2025

In Ivory Coast, dyes are widely used in traditional textile dyeing. It's a lucrative business that is attracting more and more people. Unfortunately, the wastewater from these textile dyeing units is discharged directly and continuously into the immediate environment. This poses a risk to human health and the environment. Among these dyes, the frequently used methylene blue (MB) can disrupt the balance of aquatic ecosystems by affecting the survival of aquatic organisms, inhibit photosynthesis in exposed plants, and cause irritation or toxic effects in humans in the event of prolonged exposure. This work investigated the degradation of methylene blue (MB), a model dye, by photolysis. The effects of the following parameters were studied: initial dye concentration, pH, H2O2, NaI, NaCl, and NaCl combined with H2O2 or NaI. The experiments were monitored using a UV-visible spectrophotometer. The results showed that MB can be effectively degraded by direct photolysis in a basic medium and at very low concentrations. Additionally, NaI and H2O2 had a very significant positive effect (83.77 % and 92 %) in contrast to NaCl (6.23 %). Furthermore, the treatment of MB solution was enhanced when NaCl was combined with NaI or H2O2 with a degradation rate of 88.1 and 84.9 %, respectively. The kinetic study revealed that the UV irradiation of MB can be described by both zero-order and first or second-order kinetics. In conclusion, the UV/H2O2, UV/NaI, UV/NaCl+ H2O2, and UV/NaCl+NaI systems represent very interesting alternative processes for the treatment of wastewater containing dyes at neutral pH. These methods are particularly suitable for industries involved in textile dyeing and other activities generating dye-contaminated effluents, offering an efficient and environmentally friendly solution for mitigating water pollution and meeting regulatory standards.
Variation of the Critical Frequency of the Ionospheric F2 Layer during Moderate Geomagnetic Conditions: A Study Using Data from the Ouagadougou Ionosonde Station Across Solar Cycles 21 and 22
Authors: Abidina DIABATE , Emmanuel SAWADOGO Wambi , Karim GUIBULA , Frédéric OUATTARA
Published: January 2025

This study investigates the variations in the critical frequency of the F2 layer (foF2) at the Ouagadougou ionosonde station during moderate geomagnetic activities, focusing on corotating and magnetic cloud events across the minimum and maximum phases of solar cycles 21 and 22. The analysis reveals significant perturbations in the diurnal profiles of foF2 during magnetic cloud activity at the solar minimum phase, compared to profiles observed during magnetically quiet activity. These perturbations indicate a disturbance of electrodynamic processes, including ionospheric currents and upward drifts. Conversely, corotating activity exhibits negligible impact on foF2 profiles at solar minimum phase. At solar maximum phase, the diurnal profiles observed during moderate geomagnetic activities are identical to those observed during very quiet days. Notably, ∆foF2 values during moderate activities are generally below 20% during the day but show short-lived positive storms (>20%) at night, especially near sunrise. These findings enhance our understanding of equatorial ionospheric dynamics and the influence of geomagnetic activity, contributing to improved space weather predictions and ionospheric modeling.
A Review on Cancer Diagnostic and Therapeutic Considerations in Dogs
Authors: Yadav Priyanka , Kumar Sanjeev , Singh Geetanjali , Verma Subhash , Sharma Mandeep
Published: January 2025

Cancer presents a significant health concern in dogs, similar to its impact on humans, and stands as a primary contributor to canine mortality. The elevated incidence of cancer in dogs, relative to other domesticated animals, may be attributed to their intimate companionship with humans, advanced medical diagnostics, and elevated healthcare standards that have extended their lifespans beyond typical expectations, although accompanied by a heightened susceptibility to cancer. Effective diagnosis and treatment of canine cancer hinge upon a comprehensive understanding of tumor varieties, their underlying pathophysiology, and molecular alterations affecting genes and proteins. A range of diagnostic tools is employed for detecting cancer in dogs, encompassing blood profiles, cytological evaluations, histopathology, immunohistochemistry, and various imaging methods such as computed tomography, magnetic resonance imaging, positron emission tomography, and single-photon emission computed tomography. Additionally, molecular techniques play a crucial role. Therapeutic options for addressing canine cancer encompass chemotherapy, surgical procedures, and radiation therapy. Furthermore, promising developments including cancer vaccines and novel anti-cancer medications are currently undergoing clinical trials, aiming to enhance the management of cancer in dogs. This article provides an overview of both current and emerging diagnostic and treatment approaches, whether currently available or in the experimental stage, for effectively managing cancer in dogs.
Impact of different Nano-fertilizers on Agronomic Traits of wheat under Jammu Subtropics
Authors: Reddy Boreddy Jayachandra , Kour Sarabdeep , Gupta Meenakshi , Sharma Vikas , Bansal Kanik Kumar , Singh Brijeshwar , Choudhary Puneet , Khajuria Sugandha
Published: January 2025

Among the various fertilizers, nitrogen (N), phosphorus (P) and Potassium (K) are vital for wheat cultivation, but their excessive and improper use can harm both human health and the environment. Thus, exploring alternatives like nano fertilizers, which provide a slow and controlled release of nutrients, is essential. Keeping this in view, an experiment was conducted at the Research Farm of Division of Soil Science and Agricultural Chemistry, Chatha, Jammu, Jammu and Kashmir during the rabi season of 2021-2022 and 2022-2023 to study the effects of nano NPK fertilizers on wheat cultivar ‘HD-3086’. The experiment followed a Randomized Block Design with 12 treatments and 3 replications across 36 plots. The treatments ranged from control (no fertilizers) to varying levels of recommended doses of Fertilizers (RDF) of NPK viz. 100%, 75%, 50%, combined with different numbers of foliar sprays of nano-NPK at tillering, jointing, and booting stages. The significantly higher results with respect to growth parameters and yield were recorded under treatment T8 (100% RDF [NPK] + 3 foliar sprays of nano-NPK at tillering, jointing, and booting stages) which was at par with treatment T5 (100% RDF [NPK] + 2 foliar sprays of nano-NPK at tillering, and booting stages) but showed no significant variation in harvest index. In contrast, the control treatment, which received no fertilizer, exhibited the poorest growth and yield performance at harvest.
The Role of Bioelectric Signals in Cancer Genome Regulation and Potential Therapeutic Implication: An Overview
Authors: Ajutor Lawrence John , Sani Fatima Bello , Kama Elijah Nehemiah , Ugoagwu Kingsley Ugonna , Christopher Adegbesan Abiodun , Oyedemi Daniel Temiloluwa , Adewoyin Peter Bemigho , Agbetanmije Olayinka Esther , Adekoya Adepeju Matilda , Onyeugbo Erere Godsent
Published: January 2025

Bioelectrical signals which are directed by ion channels and membrane potential (V_mem), play a crucial role in many cellular processes including proliferation and differentiation. It has also been known to influence processes such as gene expression, epigenetics, and tumor progression which are key aspects of cancer development. This study explores the role of bioelectric signaling in oncogenesis, highlighting possible therapeutic implications. An inferential review of existing literature was done to understand the possible outcomes of integrating Tumor-Treating Fields (TTFields) with traditional therapies like chemotherapy and immunotherapy. Relevant sources were analyzed to gain mechanistic insights from clinical and non-clinical studies to deduce potential therapeutic implications.
Dysregulated ion channel activity and abnormal cellular membrane potential are hallmark findings of cancer cells. Deviant bioelectric signals seen in tumors promote oncogene activation and tumor suppressor silencing. These bioelectric changes affect chromatin remodeling through pathways involving calcium signaling, histone modifications, and DNA methylation.
Therapeutically, targeting ion channels, such as potassium and sodium-proton exchangers may offer a novel strategy to disrupt tumor growth. Bioelectric stimulation, using techniques like optogenetics, can also help reprogram cancer cells to induce differentiation or apoptosis. There are also potential diagnostic advancements that leverage bioelectric markers, such as depolarized membrane potential, for early cancer detection through electrophysiological imaging and wearable sensors. Bioelectric modulation can enhance drug uptake, improve immune responses by normalizing the tumor microenvironment, and enable targeted delivery using electroporation.
Bioelectrical signals influence genome regulation and offer significant therapeutic and diagnostic potential. Further studies are recommended to provide essential insights into the potential of harnessing bioelectricity for advanced cancer management and improved patient outcomes.
Comparative Effects of Neem-coated Urea, Agrotain Urea and Nano Nitrogen on Nutrient Uptake of Paddy Crop
Authors: P Sowmya , A Madhavi , G Jayasree , D Sreelatha , S Triveni
Published: January 2025

Aims: To evaluate the impact of innovative nitrogen management strategies, including neem-coated urea (NCU), nano fertilizers, and Agrotain urea, on nutrient use efficiency (NUE), NPK uptake, and rice productivity in the Southern Telangana Zone.
Study Design: Randomized block design with 3 replications, including traditional and innovative nitrogen formulations combined with foliar-applied nano nitrogen sprays.
Place and Duration of Study: Agricultural Research Institute, Rajendranagar, during the Kharif season of 2021&2022.
Methodology: The experiment was conducted on the JGL 24423 rice variety. Treatments included varying nitrogen rates (100%, 50%, and 33% recommended dose of nitrogen [RDN]) applied as NCU (Neem Coated Urea), Agrotain UG (urea granules), or combinations with nano nitrogen sprays. Nitrogen was applied in three splits (transplanting, tillering, and panicle initiation). Nutrient uptake (NPK) was analyzed using standard laboratory methods, and statistical analysis was performed using ANOVA to assess treatment effects.
Results: The 100% RDN-STCR (Soil Test Crop Response)-based NCU treatment demonstrated the highest mean nitrogen uptake (66.8 kg ha⁻¹ in grain, 53.7 kg ha⁻¹ in straw), phosphorus uptake (18.7 kg ha⁻¹ in grain, 9.5 kg ha⁻¹ in straw), and potassium uptake (37.7 kg ha⁻¹ in grain, 120.9 kg ha⁻¹ in straw). Reduced nitrogen treatments with nano nitrogen sprays showed moderate nutrient uptake.The control and nano nitrogen sprays alone had the lowest uptake levels.
Conclusion: Nitrogen management strategies, particularly 100% RDN-STCR-based NCU, significantly enhanced NUE, nutrient uptake, and rice productivity, demonstrating their potential for sustainable rice cultivation.
Strategising Greenfield Energy Development Gap to Align with Global Carbon Reduction and Climate Goals
Authors: Oladipo Olusola Temidayo , Dienagha Ikiomoworio Nicholas , Digitemie Wags Numoipiri
Published: January 2025

The urgency of addressing climate change and meeting global carbon reduction goals, such as those outlined in the Paris Agreement, necessitates innovative approaches to energy development. Greenfield energy projects, defined as entirely new infrastructure developments, offer a unique opportunity to align energy systems with decarbonization targets. These projects are uniquely suited for achieving climate goals as they allow for the development of modern, customized infrastructure free from legacy constraints, enabling the seamless integration of renewable energy technologies and sustainable practices. However, these projects face significant challenges, including high financial risks, technological gaps, regulatory barriers, and socio-environmental issues such as community resistance and biodiversity impacts. This paper explores strategic frameworks to integrate renewable energy technologies, circular economy principles, and public-private partnerships into Greenfield projects while emphasizing lifecycle carbon footprint assessments. Additionally, it highlights the role of global collaboration in fostering knowledge sharing, standardizing carbon accounting, and aligning projects with national and regional energy transition plans. The paper recommends actionable measures such as strengthening regulatory frameworks, fostering innovation in clean energy technologies, and promoting stakeholder engagement to ensure sustainable and equitable outcomes. These strategies aim to advance Greenfield energy development as a cornerstone of the global energy transition and the achievement of climate objectives.
Construction Technology and Quality Control of Reinforced Concrete Beam and Column Joints
Authors: Wu Shaojie , Gao Yan , Tan Zilong
Published: January 2025

Reinforced concrete beam-column joints are critical components in building structures, and their construction quality directly affects the safety and stability of the entire building. This paper first introduces the construction characteristics and challenges of reinforced concrete beam-column joints, then elaborates on the construction techniques and quality control measures, and finally analyzes the precautions in the construction of reinforced concrete beam-column joints. The aim is to provide valuable references and insights for relevant engineering projects.
Socio-Economic Profile Analysis of Pisciculture Farmers in Puri District of Odisha, India
Authors: Sahoo Soubhagya Kumar , Das Kiran Sourav , Prangya Swatee
Published: January 2025

Pisciculture significantly contributes to food security, nutrition, and rural livelihood in India, the world's second-largest fish producer. Odisha, with its abundant aquatic resources, offers immense potential for pisciculture, particularly in districts like Puri, where it serves as a critical livelihood activity. However, the socio-economic attributes of fish farmers, such as education, income, and resource access, remain inadequately explored, posing challenges to sustainable development in this sector. With this background, the current study was undertaken to evaluate the socio-economic profile of pisciculture farmers in Puri district using an ex-post-facto research design and multi-stage sampling technique with purposive sampling of district, block, village and gram panchayat. Data were collected from 120 randomly sampled respondents through pre-tested, structured interview schedule followed by detailed analysis. Key variables studied included age, caste, education, pond size, annual income, farming experience, family size, house type, type of pond, ownership of pond, extension contact, and information source use. Findings revealed that 49.2% of respondents were young, 71.7% belonged to the general caste, and 35% had education only up to primary school. Most farmers (49.2%) operated ponds of 0.3–0.4 ha, and 31.7% earned annual incomes up to Rs.30,000. Additionally, 71.7% had less than five years of farming experience, while 55% had large families of more than 4 members. Pucca houses (45.80%), seasonal ponds (55.8%) and revenue ponds (44.2%) were owned by the majority. The Assistant Director of Fisheries was the most contacted authority, with newspapers as the primary information source and friends and relatives as the preferred personal information channels. These findings highlight critical socio-economic gaps among fish farmers which need targeted interventions to enhance growth of pisciculture in Puri district.
Public Satisfaction in Medan Green Public Parks: The Role of Service Quality, Facilities, and Trust
Authors: Nasution Azwar Anshory S , Lubis Suwardi , Purwoko Agus
Published: January 2025

Public satisfaction with urban parks is crucial for enhancing community engagement and well-being, yet challenges in management persist, particularly in developing countries like Indonesia. This study investigates the impact of service quality, facilities, and public trust on user satisfaction in Ahmad Yani Park, a key green public space in Medan. Ahmad Yani Park was chosen as the case study due to its strategic importance and persistent public complaints about cleanliness, inadequate facilities, and security. Using a quantitative approach, data were collected from 150 respondents through accidental sampling and analyzed via multiple linear regression. Results reveal that public trust has the strongest influence on satisfaction (β = 0.611, p < 0.001), followed by facilities (β = 0.240, p < 0.01) and service quality (β = 0.140, p < 0.05), collectively explaining 87% of overall satisfaction. These findings highlight the critical need to address deficiencies in cleanliness, facility maintenance, and security to enhance public trust and user experiences. The study’s strategic recommendations include improving cleanliness practices, establishing regular maintenance schedules, and implementing advanced security systems, such as CCTV and lockers. This research contributes to urban park management literature by providing actionable insights for creating inclusive and sustainable public spaces. Future studies should explore the long-term impacts of such interventions on community engagement in green public spaces.
INVESTIGATING RACIAL SALARY DISCRIMINATION AND THE ROLE OF BARGAINING POWER: EVIDENCE FROM THE NBA
Authors: LI WENZE
Published: July 2023

This paper investigates racial salary discrimination by analyzing an NBA dataset from 1985 to 2022. My findings reveal that non-white players receive around 10% lower remuneration than their white counterparts, after accounting for the player, team and consumer attributes. I investigate this salary gap, indicative of discrimination against black players, by studying the salary contracts under which players possess different levels of bargaining power. I find that this earning shortfall is strongly persistent under contracts where employers have monopsony and oligopsony power, suggesting that slight relaxation of the competition in the contracting environment cannot alleviate the discrimination. Nevertheless, discrimination is eliminated when players are signed under contracts that are protected by the collective power of a union. In addition, I discover that a negative demand shock (proxied by COVID-19) and a negative supply shock (proxied by lockouts) amplify this racial discrimination.
The April 2023 Issue
Authors: Uhlig Steve
Published: July 2023

This April 2023 issue contains one technical paper and four editorial notes.
The potential feasibility of mangrove crab (Scylla serrata) silvofishery aquaculture
Authors: RINALDY HENDY , ISKANDAR JOHAN , CAHYANDITO M. FANI , SUNARDI SUNARDI
Published: July 2023

Abstract. Rinaldy H, Iskandar J, Cahyandito MF, Sunardi. 2023. The potential feasibility of mangrove crab (Scylla serrata) silvofishery aquaculture. Biodiversitas 24: 3344-3354. The degradation of mangrove forests in Indonesia has reached more than 50%, and increases continuously. Sei Beduk is one of the Sub-districts in Batam City, Indonesia, that has mangrove forest damage where the density of trees per hectare is below the normal value of <1,000 trees per hectare. One approach that can be applied to overcome forest degradation is fisheries management with an ecosystem approach. This study aims to determine the suitable location for cultivating mangrove crab (Scylla serrata Forskål, 1775) and analyze the potential feasibility of S. serrata silvofishery cultivation using a quantitative approach with the Ecosystem Approach to Fisheries Management (EAFM) method. According to Slovin's calculations, a minimum of 100 people samples were obtained, and 147 samples were obtained at the time of data collection. The results showed that the location of the Perahu was highly potential for silvofishery S. serrata cultivation. The overall potential feasibility of silvofishery S. serrata cultivation in Sei Beduk, Batam was 53.10% or moderate/relatively good. The potential feasibility of S. serrata cultivation management planning is sufficient to support the sustainability of mangrove forests and allow it to be implemented. The feasible plan for managing S. serrata cultivation is to preserve ecology while improving and considering aquaculture policies and regulations. The relatively appropriate mangrove silvofishery cultivation in Sei Beduk, Batam, can provide community solutions to carry out silvofishery cultivation as a measure to overcome the problem of mangrove forest degradation, particularly in Sei Beduk, Batam.
Molecular insights into the inhibitory potential of anthocyanidins on glucokinase regulatory protein
Authors: Kenneth Christian , Anugrah Daru Seto Bagus , Julianus Jeffry , Junedi Sendy
Published: July 2023

Computational methods were used to investigate six anthocyanidins exhibiting antidiabetic activity by inhibiting glucokinase regulatory protein (GKRP) activity. Density functional theory was used to optimise the geometry of anthocyanidins and calculate their quantum chemical properties. A blind docking method was employed to conduct a molecular docking study, which revealed that delphinidin (Del), cyanidin (Cya), and pelargonidin (Pel) as potential GKRP inhibitors with the lowest binding free energy of -8.7, -8.6, and -8.6 kcal/mol, corresponding to high binding affinity. The molecular dynamics study further verified the blind docking results by showing high GKRP-F1P complex stability and high binding affinity calculated through the MM/GBSA method, upon the binding of pelargonidin. The lower RMSF values of pivotal GK-interacting residues for GKRP-F1P-Pel compared to GKRP-F1P, as a positive control, indicating pelargonidin ability to maintain the inactive conformation of GKRP through the inhibition of GK binding. The key residues that control the binding of the F1P to GKRP and anthocyanidin to GKRP-F1P were also identified in this study. Altogether, pelargonidin is anthocyanidins-derived natural products that have the most potential to act as inhibitors of GKRP and as antidiabetic nutraceuticals.
Neutrosophic Q-Ideals of Neutrosophic Q-Algebra
Authors: Granados Carlos , Das Suman
Published: July 2023

the study of neutrosophic sets in different fields has been growing in the last decade; it allows the modelling and studying of some physical, biological and behavioral phenomena. In this paper, we establish the notion of neutrosophic Q-ideal of neutrosophic Q-algebra, which is an extension of some results presented in fuzzy and intuitionistic fuzzy sets. Finally, we formulate severalconclusions.
Daily Artificial Gravity Partially Mitigates Vestibular Processing Changes Associated with Head-down Tilt Bedrest
Authors: Seidler Rachael , tays Grant , Hupfeld Kathleen , McGregor Heather , Beltran Nichole , de Dios Yiri , Mulder Edwin , Bloomberg Jacob , Mulavara Ajitkumar , Wood Scott
Published: July 2023

Microgravity alters vestibular signaling and reduces body loading, driving sensory reweighting and adaptation. The unloading effects can be modelled using head down tilt bedrest (HDT). Artificial gravity (AG) has been hypothesized to serve as an integrated countermeasure for the physiological declines associated with HDT and spaceflight. Here, we examined the efficacy of 30 minutes of daily AG to counteract brain and behavior changes that arise from 60 days of HDT. One group of participants received 30 minutes of AG daily (AG; n = 16) while in HDT, and another group served as controls, spending 60 days in HDT bedrest with no AG (CTRL; n = 8). We examined how HDT and AG affect vestibular processing by collecting fMRI scans from participants as they received vestibular stimulation. We collected these data prior to, during (2x), and post HDT. We assessed brain activation initially in 10 regions of interest (ROIs) and then conducted an exploratory whole brain analysis. The AG group showed no changes in brain activation during vestibular stimulation in a cerebellar ROI, whereas the CTRL group showed decreased cerebellar activation specific to the HDT phase. Additionally, those that received AG and showed little pre- to post-bed rest changes in left OP2 activation during HDT had better post-HDT balance performance. Exploratory whole brain analyses identified increased pre- to during-HDT activation in the CTRL group in the right precentral gyrus and the right inferior frontal gyrus specific to HDT, where the AG group maintained pre-HDT activation levels. Together, these results indicate that AG could mitigate brain activation changes in vestibular processing in a manner that is associated with better balance performance after HDT.
Terpenes, Terpenoids and Steroids: Properties, Biosynthesis and Functions
Authors: Maswal Masrat , Pandita Meeshu , Bashir Shabnum
Published: July 2023

Terpenes belong to the largest class of secondary metabolites consisting of
five carbon isoprene units which are assembled through innumerable patterns
generating diverse structural motifs. Terpenes are linear or cyclic hydrocarbons,
whereas terpenoids are oxygen-containing terpene analogues found in all living
organisms. Steroids are a subclass of terpenoids that are biosynthesized from terpene
precursors. Terpenes, terpenoids and steroids are all derived from five-carbon isoprene
units assembled and arranged in different ways generating thousands of structurally
varied molecules. Terpenes and terpenoids are widely explored as biomaterials and
biofuels while steroids are used as drugs to increase protein synthesis in animals
besides their anti-inflammatory, anticancer and other properties. In this chapter, we
discuss the properties, functions and biosynthesis of terpenes and terpenoids in general
and steroids in particular to better understand their functions and prospective
applications.
Przemysł spożywczy krajów Unii Europejskiej w latach kryzysu gospodarczego 2007-2011
Authors: Żelazowska-Przewłoka Anna
Published: July 2023

Celem opracowania było przedstawienie zmian w przemyśle spożywczym w krajach Unii Europejskiej w latach kryzysu gospodarczego 2007-2011. Na podstawie danych zawartych na stronach Komisji Europejskiej i w biuletynach Data & trends of the European Food and Drink Industry przeanalizowano wielkości przemysłu spożywczego ogółem oraz w krajach Unii Europejskiej. Stwierdzono, że mimo kryzysu gospodarczego zmiany te były niewielkie.
The development and significance of foreign trade in agri-food products in selected preferential trade agreements
Authors: Pawlak Karolina
Published: July 2023

The aim of the paper is to present the development tendencies and the significance of agri-food trade in selected preferential trade agreements in both Americas, Asia and Africa. The analysis included the values of trade turnover both within the region and in exchange with third countries, the share of the agri-food trade in the total trade in the region and the share of the regions under investigation in the global agri-food trade. The analysis allowed us to indicate the greatest global exporters and importers of agri-food products. The assessment of trade creation and trade diversion effect in agri-food trade of selected trade agreements was also possible.
Effects of exogenous abscisic acid on antioxidant system of salt tolerant and salt sensitive cotton cultivars
Authors: Kuldoshova K.M. , Akhunov A.A. , Khashimova N.R. , Ziyavitdinov J.F.
Published: July 2023

Salinity is one of the most imperative global problems that affect crop productivity on a large scale. Salinity impairs plant growth and development by imposing various stresses. Therefore it is vital to decode those stress factors and identify possible solutions to improve agriculture productivity. However, the adaptive mechanisms under saline conditions of glycophytes have not been studied. The present study was undertaken to determine the effects of exogenous abscisic acid (ABA) on salinity tolerance in cotton plants. Some patterns of resistance development were revealed on the seedlings of two cotton cultivars, a salt-tolerant (Gulistan) and a salt-sensitive one (C-4727). Moreover, the antioxidant potentials of these cultivars were compared. The activities of ascorbate peroxidase (APX), super-oxide dismutase (SOD), as well as the quantity of endogenous ABA, malondialdehyde (MDA), and free proline (Pro) were determined in control and post treatment. Our results demonstrate significant differences between the salt- tolerant and sensitive cotton seedlings in response to saline stress, i.e., high levels of Pro and endogenous ABA, but lower MDA concentrations, and higher activity of APX and SOD for the salt-tolerant cultivar, Gulistan, as compared to the salt stress-sensitive cultivar C-4727.
Incorporación de las redes sociales como estrategias pedagógicas en la formación médica
Authors: Jurado Zambrano Leonardo Fabio , Murcia Zuluaga María Camila , Saavedra Cuenca Tatiana Andrea
Published: July 2023

Es innegable el crecimiento que han venido experimentando las redes sociales como Facebook, Twitter e Instagram las cuales surgieron como un mecanismo de interacción social, migrando paulatinamente a una diversificación de sus usos en entornos políticos, laborales y académicos. Así, desde el ámbito académico, las redes sociales emergen de manera progresiva a las dinámicas micro curriculares propuestas en la praxis del sistema didáctico de Aprendizaje Basado en Problemas (ABP) de la Fundación Universitaria Sanitas, UNISANITAS.
Se considera entonces que el Aprendizaje Basado en problemas puede articularse con las redes sociales para favorecer el desarrollo de un aprendizaje significativo forjado a partir de las experiencias cotidianas y en relación con los espacios y recursos en que existe la oportunidad de aprender y de interactuar con otros y con el conocimiento. 
De esta manera, el propósito de este artículo es mostrar los resultados del desempeño académico de los estudiantes de quinto semestre con el uso de redes sociales para el estudio de los temas de microbiología orientados al aprendizaje de virus, parásitos y hongos de importancia médica y la percepción de estudiantes y docentes a cerca de estas actividades desarrolladas durante el semestre 2019-1. 
Para el cumplimiento de este objetivo, se implementó una metodología de cuantitativo en el nivel descriptivo, cuyo objetivo se orientó por sistematizar la experiencia, evidenciando en los resultados que esta implico una proceso favorable e innovador que contribuye didácticamente a los propósitos del aprendizaje basado en problemas, en lo que refiere al trabajo colaborativo, al aprendizaje significativo y esencialmente a la intención de formar de manera integral a los profesionales de salud.
competencias informáticas e informacionales de profesores y estudiantes universitarios en época de pandemia
Authors: Forero Santamaria Juan Pablo
Published: July 2023

La pandemia generada por el virus SARS-CoV-2 además de ser una situación de atención urgente en el ámbito mundial en materia de salud pública, fue precursora y motivadora del desarrollo del conocimiento y comportamiento del ser humano. El distanciamiento obligatorio y así mismo la interrupción temporal de actividades en el sector educativo entre otros diversos sectores de interés, generaron incertidumbre y de igual forma incentivaron acciones de respuesta producidas en cortos periodos de tiempo, con el fin de disminuir el nivel de impacto negativo en los procesos académicos. Este fenómeno en la salud pública y sus efectos en sindemia, implicó para las instituciones la toma de decisiones acertadas y la planeación inmediata por parte de los cuerpos directivos en las IES; Así, se produjeron en tiempo récord actividades gerenciales, administrativas, operativas y logísticas que apoyaron en el proceso de adaptación a docentes y estudiantes universitarios. En el presente artículo, se busca reflexionar y evidenciar los aspectos relevantes originados en docentes y a través de ellos en estudiantes, que les permitieron adquirir y mejorar competencias informáticas, digitales e informacionales, utilizadas para ajustar, reactivar y mantener el desarrollo de actividades académicas. Este análisis permite entender los retos en educación superior asumidos para afrontar la crisis del confinamiento y la forma como las Universidades y en especial la Fundación Universitaria Sanitas, atendió a las necesidades de acceso al conocimiento, proporcionando dispositivos académicos que asegurasen el desarrollo de las competencias informáticas e informacionales que facilitaran el desarrollo del Sistema Didáctico de Aprendizaje Basado en Problemas, bajo la modalidad de presencialidad mediada por tecnologías de la información y la comunicación.
Retos para los procesos de visibilidad nacional e internacional en las Instituciones de Educación Superior
Authors: Cardona Duque Héctor Henry
Published: July 2023

La visibilidad nacional e internacional de las Instituciones de Educación Superior, conforma una plataforma que propende por el mejoramiento continuo y la calidad académica, aportando una visión global, intercultural y humanista al desarrollo integral de los profesionales, en el marco del respeto, la comprensión y aceptación de la diversidad, propiciando escenarios para el desarrollo de competencias laborales con alcance local, regional, nacional e internacional.El objetivo de esta reflexión, se orienta por apoyar el desarrollo de los programas académicos ofertados por la Instituciones de Educación Superior Colombianas, promoviendo en el marco de la cooperación, la implementación de acciones conducentes al fortalecimiento de líneas de acción relacionadas con la internacionalización del currículo, la movilidad académica entrante y saliente de los miembros de la comunidad y desde ello, el apoyo en el cumplimiento de las funciones sustantivas de docencia, investigación y proyección social.
En ese sentido, en la experiencia alcanzada por la Fundación Universitaria Sanitas, se reconoce que la visibilidad nacional e internacional de sus programas académicos ha implicado un permanente proceso de desarrollo que basado en las funciones misionales de docencia, investigación y vinculación con el sector externo y articuladas al sistema didáctico de aprendizaje basado en problemas (ABP), promueve acciones de cooperación interinstitucional e intersectorial, para facilitar académica y administrativamente un sistema de oportunidades para el fortalecimiento de competencias profesionales en una aldea global del conocimiento contextualizada por la diversidad y la pluralidad cultural.
INTERVENÇÕES DO ENFERMEIRO ESPECIALISTA EM SAÚDE INFANTIL E PEDIÁTRICA: REFERENCIAÇÃO DA CRIANÇA EM CUIDADOS PALIATIVOS
Authors: Couto Ana , Silva Sofia , Fernandes Rita , Barcelos Olívia , Marques Goreti
Published: July 2023

Introdução: Os Cuidados Paliativos Pediátricos objetivam melhorar a qualidade de vida da criança, jovem e família, portadora de doenças crónicas complexas, limitantes ou ameaçadoras de vida. No entanto, várias são as que, mesmo com critérios, nunca chegam a ser referenciadas, e as que são, tendem a ocorrer tardiamente na trajetória da doença. Objetivos: Identificar produção científica relativa à temática da Referenciação em Cuidados Paliativos Pediátricos. Metodologia: Revisão Integrativa da Literatura efetuada nas bases de dados: CINAHL Complete; MEDLINE Complete; Nursing & Allied Health Collection: Comprehensive e Cochrane Central Register of Controlled Trials, disponíveis motor de busca EBSCO, publicados entre 2012 e 2022. A seleção e análise de relevância dos artigos foi efetuada pelos revisores de forma independente. Resultados: Dos 231 artigos iniciais foram selecionados 13 artigos, segundo critérios previamente definidos. Verifica-se a necessidade de identificar o mais precocemente possível, as oportunidades de referenciação da criança e família para Cuidados Paliativos Pediátricos, reconhecendo os seus benefícios. As crenças e atitudes dos profissionais de saúde, e a ausência de conhecimento relativa aos Cuidados Paliativos Pediátricos, poderão ser barreiras à referenciação. Conclusão: Foi evidenciada a importância e os benefícios da precoce e adequada referenciação para Cuidados Paliativos Pediátricos, e de que forma o Enfermeiro Especialista em Saúde Infantil e Pediátrica pode intervir no sentido de facilitar o processo.
Effect of Variations of Drilling Bolt Distances on Bending Strength of Composite Wood Beams
Authors: Noviadi Satia Cahya , Sugiartha I Wayan , Fajrin Jauhar
Published: July 2023

Wood products that are currently growing rapidly in many places in the world are laminated blocks (glulam). Laminate beam has many advantages in terms of size, strength and artistic. However, this laminated beam has a few drawbacks in terms of providing tools and materials for some areas. The laminated beam itself uses an adhesive material which is relatively expensive and requires a compression tool in its implementation. Therefore, an alternative is given in the form of composite beams. Composite beams that have developed so far use shear connectors in the form of bolts, nails, and pegs as the connecting tool. Meanwhile, shear connectors using drilling bolts have never been done. Therefore, based on this, it is necessary to research composite wood beams with an alternative, namely using drilling bolts as shear connectors in order to obtain the effect of variations in the distance of drilling bolts on the flexural strength of composite beams. The results of the flexural strength test obtained the strength of the composite beam with shear connectors with the largest distance of 3.125, followed by beams with shear connecting distances of 6.25 cm, 12.5 cm and 25 cm. This shows that the closer the shear connecting distance, the greater the strength obtained, with the percentage increase in variation of 31.5%, 38.737% and 46.072%, respectively.
Therapist-Supported Digital Mental Health Intervention for Depressive Symptoms: A Randomized Clinical Trial
Authors: gould Christine
Published: July 2023

Depression is a chronic and debilitating mental disorder. Despite the existence of several evidence-based treatments, many individuals suffering from depression face myriad structural barriers to accessing timely care which may be alleviated by digital mental health interventions (DMHI). Accordingly, this randomized clinical trial (ClinicalTrials.gov: NCT04738084) investigated the efficacy of a therapist-supported DMHI, the Meru Health Program, among people with elevated depression symptoms (N=100, mean age 37). Recruited participants were randomized to a therapist-supported DMHI (n=54) or a waitlist control (n=46) condition for 12 weeks. The DMHI group had greater decreases in depression symptoms compared to the waitlist control (d=-0.8). A larger proportion of participants in the DMHI reported a minimal clinically important difference (MCID) in depression symptoms than waitlist control participants (39.1% vs. 9.8%, Chi-square (1)=9.90, p=.002). Similar effects were demonstrated for anxiety symptoms, quality of life, insomnia, and resilience. The results confirm the utility of therapist-supported DMHIs in reducing depression symptoms and associated health burdens.
Identifying Regional Stakeholder-Informed Priorities for Adult Social Care Research: A Mixed-Method Study in Kent, Surrey, and Sussex
Authors: Keemink Jolie Rosanne , Sharp Rebecca Jane , Dargan Alan Kenyon , Forder Julien E.
Published: July 2023

Context: There is an urgent need for sustainable change in the social care sector, and research plays an essential role in the identification of priority areas. Thus far, there have been few priority setting exercises within adult social care research. The current study explores regional priorities for adult social care research in Kent, Surrey, and Sussex. Stakeholders were consulted from the starting point of the project, ensuring that the identified research priorities were fully informed by the people that the subsequent research will have an impact on.
Objectives: Our main aim was to identify research priorities for adult social care within the region, and more specifically, relevant activities within these priority areas that could benefit from evaluation.
Methods: We employed a mixed-method design using online focus groups with social care professionals (N = 37) and members of the public (N = 7), and an online survey following the focus groups (N = 28). Focus group discussions were informed by themes based on The Care Act 2014.
Findings: Content analysis was used to analyse discussions, which yielded a list of 46 actionable research questions. Rankings of discussion themes were produced to establish order of importance.
Limitations: We approached the ranking of priorities only at a higher-order theme level, and not at the level of the specific questions.
Implications: The extensive list of research questions produced in this study supports social care researchers to conduct studies that address pressing issues for care systems and the public.