bluuebunny/crossref_metadata_2025 huggingface dataset:
Deu match? Uma introdução às técnicas de pareamento
Authors: Schaefer Bruno Marques , Figueiredo Filho Dalson Britto
Published: December 2023

Resumo Como inferir causalidade a partir de dados observacionais? Este artigo apresenta uma introdução intuitiva ao pareamento, técnica estatística útil para identificar relações causais em desenhos de pesquisa não experimentais. Metodologicamente, apresentamos as principais características do matching a partir de três exemplos: a) o efeito das escolas militares sobre aprendizagem; b) o impacto do Bolsa Família sobre a propensão em votar no Partido dos Trabalhadores; e c) a influência do gênero sobre o desempenho eleitoral. Mostramos a implementação computacional no R e explicamos a interpretação substantiva dos resultados. Com o objetivo de aumentar o potencial didático da pesquisa, disponibilizamos todos os materiais de replicação, o que facilita que estudantes e profissionais utilizem os dados e scripts em suas atividades de estudo e trabalho. Com este artigo, esperamos difundir o uso de técnicas quase-experimentais nas Ciências Sociais e incentivar a replicabilidade como estratégia de ensino de análise de dados.
EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA: ESPAÇO-TEMPO DE FORMAÇÃO HUMANA?
Authors: Zatti Vicente
Published: December 2023

RESUMO O presente artigo, situado no campo da filosofia da educação, tematiza a educação profissional e tecnológica enquanto espaço-tempo de formação humana. Para defender a tese da precedência da formação humana e cidadã, estrutura o argumento em três partes: na primeira, revisita os gregos antigos, fundadores da ideia educativa e raiz do dualismo entre formação profissional e formação geral; na segunda, analisa a concepção de educação omnilateral em Marx, a qual critica a herança da educação clássica e propõe a superação de tal dualismo pela união entre ensino e trabalho; e na terceira, com base na ideia-força grega da skholé, reinterpretada por Rancière e Masschelein, pensa a educação profissional e tecnológica como espaço-tempo de formação humana, enquanto possibilita o tempo livre que coloca em suspensão a lógica desigual do mundo do trabalho.
Morphophysiological responses of Conilon coffee matrix plants in a super-dense clonal garden
Authors: Silva Josimar Aleixo da , Esposti Marlon Dutra Degli , Senra João Felipe de Brites , Comério Marcone , Conceição Amanda Oliveira da , Zacarias Alex Justino , Milheiros Idalina Sturião , Silva Uliana Ribeiro , Silva Fernanda Gomes da , Raimundo Eduarda Gonçalves
Published: December 2023

Abstract The objective of this work was to evaluate the morphophysiological responses and cutting production of clones of Conilon coffee (Coffea canephora) cultivars in a super-dense clonal garden in the state of Espírito Santo, Brazil. The super-dense clonal garden was built in 2019 using 39 clones: 9, 9, 9, and 12 of cultivars Centenária ES8132, Diamante ES8112, ES8122 (Jequitibá), and Marilândia ES8143, respectively. The experiment was carried out in a randomized complete block design, with three replicates. Cutting production and the following morphophysiological traits were evaluated at 9 and 18 months after planting: chlorophyll index, normalized difference vegetation index, plant height, canopy height, canopy diameter, number of shoots, number of viable cuttings, number of leaves, fresh leaf mass, and plant fresh and dry matter mass. The super-dense clonal garden caused different morphophysiological responses among the studied clones. In general, clones C2, C5, C6, C8, D1, D8, D9, J8, M2, M9, M10, and M12 showed a higher mean cutting production, whereas C4, J1, J4, M4, and M5 were the most sensitive to the super-dense regime. Under these conditions, it is recommended to increase the proportion of matrix plants of the latter clones.
Counting of shoots of Eucalyptus sp. clones with convolutional neural network
Authors: Araújo Júnior Carlos Alberto , Oliveira Leandro Silva de , Eça Gabriel Augusto
Published: December 2023

Abstract The objective of this work was to investigate the use of the You Only Look Once (YOLO) convolutional neural network model for the detection and efficient counting of Eucalyptus sp. shoots in stands through aerial photographs captured by unmanned aerial vehicles. For this, the significance of data organization was evaluated during the system-training process. Two datasets were used to train the convolutional neural network: one consisting of images with a single shoot and another with at least ten shoots per image. The results showed high precision and recall rates for both datasets. The convolutional neural network trained with images containing ten shoots per image showed a superior performance when applied to data not used during training. Therefore, the YOLO convolutional neural network can be used for the detection and counting of shoots of Eucalyptus sp. clones from aerial images captured by unmanned aerial vehicles in forest stands. The use of images containing ten shoots is recommended to compose the training dataset for the object detector.
Selection of superior cowpea lines derived from local cultivars for the Brazilian semiarid region
Authors: Lopes Anna Flávia de Sousa , Aragão Walter Frazão Lelis de , Damasceno-Silva Kaesel Jackson , Rocha Maurisrael de Moura
Published: December 2023

Abstract The objective of this work was to select superior cowpea lines derived from local cultivars for the semiarid region of southeastern Piauí, Brazil. A total of 38 genotypes (36 lines and two commercial cultivars) were evaluated in a randomized complete block design, with two replicates, in the municipality of Ipiranga do Piauí, in the state of Piauí. The following traits were evaluated: number of days to the onset of flowering, pod length, number of grains per pod, weight of 100 grains, commercial grain quality, and grain yield. Deviance analyzes were performed using the restricted maximum likelihood and best unbiased predictor approach, the parameters and genetic values were estimated, and simultaneous selection was carried out via the sum of ranks index. The likelihood ratio test showed a significant difference between the evaluated genotypes. Lines 36, 5, 24, 8, 2, 23, 29, 28, 34, 6, 19, 11, 7, and 20 are superior for the set of evaluated traits and, therefore, are the most promising to compose the advanced trial of the cowpea breeding program and to generate cultivars for family farmers in the semiarid region of southeastern Piauí.
Identification of Eimeria spp. in domestic chickens raised in alternative poultry production systems in the State of São Paulo, Brazil
Authors: Soares Júnior José Carlos , Itoyama Bruno Ferraz , Beretta Bruna Matarucco Sampaio , Hossotani Camila Michele de Souza , Silva Maria Santa Cardoso , Silva Giane Serafim da , Nakamura Alex Akira , Lopes Flávia Lombardi , Meireles Marcelo Vasconcelos
Published: December 2023

Abstract The objective of this study was to identify Eimeria spp. in alternative poultry production systems (APPS) in the State of São Paulo, Brazil. Fecal samples (168) and DNA extracted from fecal samples obtained in APPS located in different Municipalities in the State of São Paulo (93) were examined by microscopy or genera-specific PCR (ITS-1 locus). Samples positive for Eimeria spp. were examined using Eimeria lata, Eimeria nagambie, and Eimeria zaria species-specific PCR protocols (ITS-2 locus) and another E. lata-specific PCR (candidate IMP1 genomic locus) followed by molecular cloning (E. lata and E. zaria ITS-2 amplicons) and genetic sequencing. All positive DNA samples were also submitted to genera-specific nested PCR (18S rRNA gene) followed by next-generation sequencing to identify Eimeria spp. Eimeria nagambie, E. zaria, and Eimeria sp. were identified by ITS2-targeted species-specific PCRs and genetic sequencing. Next-generation sequencing identified, in order of prevalence: E. nagambie; Eimeria acervulina; Eimeria mivati; Eimeria praecox; Eimeria brunetti; Eimeria mitis; Eimeria sp.; Eimeria maxima; E. zaria, and Eimeria necatrix/tenella. Our results confirmed, for the first time in Brazil, the identification of E. nagambie, E. zaria, and Eimeria spp. ITS-2 and 18S rRNA gene sequences not yet described in Brazil.
Bullying en la educación superior, bullying universitario
Authors: Bulut Sefa , Crescenzo Pietro , Bukhori Baidi
Published: December 2023

Objetivo: Este estudio tuvo como objetivo explorar los incidentes de intimidación y maltrato de estudiantes universitarios por parte de miembros de la facultad, testigos, el tipo de hostigamiento, dónde se producen principalmente los acosos y los maltratos, cómo se han enfrentado a estos hechos, cómo han resuelto el incidente, las razones del hostigamiento y los malos tratos, frecuencia de los mismos, el tipo observado de bullying y similitudes culturales. Diferencias en los comportamientos de bullying y características de los miembros de la facultad que realizan el bullying.
 
Metodología: Un total de 2646 estudiantes de una universidad estatal de un tamaño mediano que estudiaban en las distintas facultades de la universidad seleccionada. Participaron voluntariamente para realizar una encuesta impulsada por el concepto de intimidación de Olweus.
 
Resultados: Los resultados revelaron que el 10 % de los estudiantes fueron amenazados con una calificación inferior o reprobada, el 21 % dijo que no creía en una investigación justa, incluso si podían presentar una queja ante las autoridades pertinentes de la universidad. Solo el 5 % de los estudiantes mencionó haber presentado una queja verbal informal. El 18 % informó que el acoso era muy importante y muy estresante para ellos. Entre estos, el 31 % de los estudiantes fue testigo de la amenaza de un miembro de la facultad a los estudiantes de una manera poco correcta. Los varones de la facultad eran 4 veces más propensos que los miembros femeninos de la misma a intimidar a los estudiantes, o comportarse de manera no cívica. El profesor asistente o los miembros más jóvenes de la facultad tienden a comportarse de manera más negativa que los profesores de mayor rango o más antiguos. Parece que la mayoría de los incidentes ocurren durante la clase (11 %) o antes de que comience la misma (1,6 %).
 
Conclusiones: Los resultados muestran que el acoso académico es un fenómeno universal y aparece en todos los niveles de la educación. A pesar de que existen diferencias culturales y departamentales, el acoso todavía es común en todos los niveles de educación de todas las culturas. El bullying tiene consecuencias negativas en los estudiantes; afecta perniciosamente su salud mental, integración escolar y logros académicos. Por lo tanto, los responsables de la administración escolar deben establecer pautas claras para las relaciones entre el profesorado y los estudiantes; y proporcionar ayuda de asesoramiento y acompañamiento para quienes lo necesiten.
Menü Mühendisliği Yöntemlerinin Karar Alma Sürecindeki Farklılıkları: Örnek Olay İncelemesi
Authors: ENES Kemal , KOŞAN Levent
Published: December 2023

Menüler restoranlardaki müşterilerin ve işletmelerin birbirleri ile iletişim kurmasını sağlayan araçlardır. Varlıklarını sürdürebilmek isteyen restoranlar beğenilen ve işletmeye kar sağlayan ürünleri belirleyebilmelidir. Menü mühendisliği, işletmelerin menü ile alması gereken stratejik kararları almalarını sağlayan istatistiki yöntemlerdir. Yapılan çalışmada bu amaçla kullanılan yedi farklı menü mühendisliği yöntemi alakart servis yapan bir restoranın ana yemekleri üzerinden karşılaştırılmıştır. Sonuç olarak, karşılaştırılan her menü mühendisliği yöntemi farklı sonuçlar vermektedir. Bu sebeple, işletmeler yönetsel kararlar alırken sadece bir menü mühendisliği yöntemi kullanmak yerine birden fazla yöntemi önceden belirledikleri amaçlar doğrultusunda kullanması gerekmektedir. Ayrıca genel sonuçlar ile birlikte ürün bazında da değerlendirmelerin yapılması daha etkin kararlar alınmasını sağlamaktadır.
Legal Consciousness of Subjects Endowed with a Special Status: Features and Forms of Manifestation
Authors: Sumenkov Sergey
Published: December 2023

The article considers various aspects of the legal consciousness of special subjects of law. The criteria for a special status in legal relations are indicated. It is determined that a special subject can be represented as a collective, community or individual. A general idea of the legal definition of «legal consciousness», its structural components and specific elements is given. Ordinary and professional legal consciousness, group and individual are distinguished. It has been established that any legal consciousness can be formed using the following methods: imitation, identification, interiorization and internalization. As a result, it is noted that the diversity of existing typical patterns of legal consciousness exacerbates the complexity of the scientific search for the distinctive features of the legal consciousness of special subjects of law. The features of the expression of legal consciousness of special participants in legal relations are studied. In particular, the negative and positive aspects of such a manifestation are illustrated using various examples. It is indicated that there are a number of characteristic elements that determine the influence on the legal consciousness of subjects endowed with a special status. Among them, one can single out distinctive properties that affect legal ideology and legal psychology. The special nature of the legal life of special subjects leaves an imprint on their legal consciousness.
Various forms of manifestation of the legal consciousness of participants in legal relations, endowed with a special status, are considered. A paradigm is derived that the format of a person›s legal consciousness depends on his general assessment of the existing legal reality. A list of forms of manifestation of the legal consciousness of subjects with a special status has been determined, which can be divided into eight types: legal nihilism, skepticism, cynicism, realism, conformism, fetishism, infantilism and idealism.
Works Created by Artiﬁcial Intelligence Technologies
Authors: Belkova Elena
Published: December 2023

In the context of the growing use of artificial intelligence technologies, including in the field of intellectual property, civil law science is tasked with developing new conceptual approaches to the legal assessment of the results of activities related to the use of artificial intelligence technologies. The current theory of copyright does not apply to such an object as a work generated by artificial intelligence technology, since artificial intelligence itself is the result of human creative activity. The article considers the possibility of recognizing the qualities of the subject of law in robots with artificial intelligence. Approaches to understanding the work created by artificial intelligence technologies as an object of intellectual rights and its place among other objects to which intellectual rights arise are analyzed. The question of authorship of works generated by artificial intelligence technologies and subjects with intellectual rights to these results is being investigated. It is concluded that it is impossible to recognize authorship for works created by artificial intelligence technologies due to the latter›s lack of legal personality.
It is proposed to amend the list of objects of intellectual rights, taking into account the possibilities of artificial intelligence technologies, to produce works in the field of science, literature, art. The lack of personal non-property rights to such works is justified. Entities that have an exclusive right to works generated by artificial intelligence technologies have been identified – technology developers. Proposals have been made to amend Russian civil law.
Mediatization of Soviet Cultural Patterns in Soviet Print Media for Children: Analytical Review
Authors: Musorina Olga , Dubrovskaya Tatiana
Published: December 2023

This paper provides a review of contemporary literature (both by Russian and foreign researchers) on Soviet children print media. The project constructed the model of Soviet society in the 1970–1980s presented in the Soviet children print media of that period. The authors discuss the existing approaches to Soviet media practices with a focus on the potential for their own research. The basic assumption for the review is admitting the process of reading as an essential social practice in the USSR, supported by both the government and citizens. A large part of the reading population was young generation who became a target audience of education policies implemented by the Soviet mass media. The authors distinguished between three groups of literature sources: 1) studies that analyzed Soviet culture policies and creation of “the new citizen/man”; 2) studies that focused on the development of central (all-Soviet) and regional mass media from 1917 to 1980-s. This group considers children print media as a functionally separate subtype of the Soviet mass media; 3) studies that examined the representations of Soviet political and social models in children mass media. The findings revealed that the problem under scrutiny proves important and highly attractive for scholars with a particular emphasis on two interrelated aspects of children’s media — promoting universal axiological guidelines for a younger generation as well as being an instrument of propaganda. In conclusion, the authors identified their research niche area as finding out discursive mechanisms (linguistic, semiotic and strategic) as lying in the foundation of ideologically motivated and non- ideological representations of the Soviet society.
Spor Bilimleri Öğrencilerinin Teknolojik Tutum Düzeyleri ile Medya Okuryazarlık Algıları Arasındaki İlişkinin İncelenmesi
Authors: KURTULDU Tansu , GUNAY Mehmet , DURMUŞ Gamze , KARACAN DOĞAN Pınar
Published: December 2023

Bu araştırmada, spor bilimleri öğrencilerinin teknolojik tutum düzeyleri ile medya okuryazarlık algıları arasındaki ilişkinin bazı değişkenler açısından incelenmesi amaçlanmıştır. Çalışmada, nicel araştırma yöntemlerinden biri olan ilişkisel tarama modeli kullanılmıştır. Veri toplama aracı olarak; araştırmacılar tarafından hazırlanan “Kişisel Bilgi Formu”, “Teknolojiye Yönelik Tutum Ölçeği (TYTÖ)” ile “Medya Okuryazarlık Algı Ölçeği (MOAÖ)” kullanılmıştır. Araştırmanın evrenini Karabük Üniversitesi Hasan Doğan Beden Eğitimi ve Spor Yüksekokulu lisans öğrencileri oluşturmaktadır. Araştırmanın örneklemini bu öğrenciler içerisinden seçkisiz örnekleme yöntemi ile seçilen 100 kadın 114 erkek olmak üzere toplam 214 kişi oluşturmaktadır. Verilerin analizinde; değişkenler arasındaki ilişkinin belirlenebilmesinde t-Testi ve tek yönlü varyans analizi (ANOVA), ölçekler arasındaki ilişkinin belirlenebilmesi için Pearson Korelasyon analizi kullanılmıştır. Araştırma verilerinden
elde edilen sonuçlara göre, öğrencilerim TYTÖ’nin orta düzeyde ortalamaya sahip olduğu, MOAÖ’nin de “medya araçlarının kullanımı” alt boyutunun en yüksek, “üst bilişsel medya farkındalığı” alt boyutunun ise en düşük ortalamaya sahip olduğu görülmektedir. Elde edilen bulgular, öğrencilerin teknolojik araçları kullanma konusunda yatkın olduklarını, ancak medya içeriklerini eleştirel bir bakışla inceleme konusunda daha sınırlı bir bilince sahip olduklarını ortaya koymaktadır. Bu, eğitim programlarında medya okuryazarlığının daha etkin bir şekilde ele alınmasının gerekliliğini
vurgulamaktadır. Son olarak, öğrencilerin, teknolojiye yönelik tutumları arttıkça medya okuryazarlık algı düzeylerinin de artış gösterdiği söylenilebilir.
Okul Yöneticilerinin Teknolojik Liderlik Öz Yeterlik Algıları
Authors: YUMUŞAK Şemsi , ÇORUK Adil
Published: December 2023

Bu araştırmanın amacı, temel eğitim kademesinde (ilkokul ve ortaokul) görev yapmakta olan okul yöneticilerinin güncel teknoloji uygulamalarını okul yönetiminde, eğitim süreçlerine uygun olarak kullanmak konusunda sahip oldukları teknolojik öz yeterlik algılarını ortaya çıkarmaktır. Araştırma var olan bir durumu betimlediğinden “tarama modeli” şeklinde düzenlenmiştir. Araştırmanın evrenini, Çanakkale merkez ve ilçelerinde temel eğitim kademesindeki (ilkokul, ortaokul) devlet okullarında görev yapan 198 okul yöneticisi oluşturmaktadır. Çanakkale il genelinde temel eğitim kademesindeki (ilkokul, ortaokul) tüm okullara ulaşılabildiğinden araştırmada örneklem alma yoluna gidilmemiştir. Araştırmada veri toplama aracı olarak Banoğlu’nun (2012) geliştirmiş olduğu “Eğitim Yöneticilerinin Teknoloji Liderliği Yeterlikleri Ölçeği”nden faydalanılmıştır. Araştırmadan elde edilen tüm veriler SPSS 26.0 programı aracılığıyla analiz edilmiş ve veriler analiz edilirken, yüzde, ortalama, t testi, frekans, tek yönlü varyans analizi (One-Way ANOVA) kullanılmıştır. Araştırma bulguları okul müdürlerinin teknolojik liderlik öz yeterlik algılarının tüm boyutlarında kendilerini büyük oranda yeterli gördüklerini göstermektedir. Teknolojik liderlik öz yeterlik algıları cinsiyet, medeni durum, eğitim durumu, teknoloji yönetimi ve liderlik/yöneticilik ile ilgili hizmet içi eğitime dâhil olma durumu değişkenlerinden etkilenirken, hizmete ait çalışma yılı değişkeninden etkilenmemektedir. Ülkemizde okul yöneticisi yetiştirmeye yönelik bir programın olmaması sebebi ile araştırmaya ait bulguların bu yönde yapılacak olan çalışmalar için kaynak teşkil edebilmesi beklenmektedir.
The Effect of Knowledge Management in Healthcare Services: A Systematic Review
Authors: Ayatulloh Daviq , Nursalam Nursalam , Kurniawati Ninuk Dian
Published: December 2023

The quality of service at health facilities needs to be improved, one of the main keys is the service provided by health workers. The aim of this systematic review was to analyze the effectiveness of knowledge management in healthcare. The systematic review was carried out in March-April 2020 with a range of article search times from 2016-2020 using 5 electronic databases (Scopus, PubMed, Science Direct, CINAHL and ProQuest). The Center for Review and Dissemination and the Joanna Briggs Institute Guideline were used to assess the quality and PRISMA's checklist for this review guide. The literature search described four keyword groups based on Medical Subject Heading (MeSH) and the search description was (knowledge management*' OR 'SECI knowledge management') AND ('health care' OR hospital). The article searched was found 13 articles suitable with the eligibility criteria, the results of the systematic review found that knowledge management had the effectiveness to provide information and knowledge processes, improve decision-making abilities, improve performance and quality of health services and increase organizational effectiveness. As health service providers, hospitals and other health care institutions must continue to improve the quality of services. By improving the quality of services, it is expected to be able to answer the demands of the community to always provide optimal health services. With the application of good knowledge management, ideas and creativity from the workforce will be created in creating health service innovations.
The Effect of Disaster Education on The Ability of Adolescents to Recognize COVID-19 Prevention
Authors: Setiyawan Setiyawan , Nugraha Andri
Published: December 2023

Disaster education to reduce disaster risk in adolescence is essential. An infectious disease that is currently spreading is covid-19. Emerging epidemiological reports of covid-19 in children show that, while they are less likely to become infected and to have the severe disease than adults, children are vulnerable to the coronavirus pandemic. This research aimed to find out the effect of disaster education on children's ability to recognize Covid-19 prevention. This research design is quasi-experimental with a one-group pretest-posttest design approach. Disaster education intervention Covid-19 covers disaster aspects (prevention, detection, and response phases). The research instrument uses a questionnaire on students' ability to recognize covid-19 prevention. Data analysis using the Wilcoxon test showed p-value of 0.000. There is an effect of providing disaster education on children's ability to recognize covid-19 prevention. The early introduction of disaster or disease outbreaks and their prevention are the concrete means that need to be given to the younger generation to increase the children's knowledge and shape alertness behavior in dealing with the disaster or disease outbreaks.
Betel Leaf Extract’s Effect (Piper Batle Linn) on The Healing Process of Incision Wounds in Rats (Rattus Norvegicus)
Authors: Suharto Idola Perdana Sulistyoning , Ramayanti Eva Dwi , Yunalia Endang Mei , Ulfa Novia
Published: December 2023

An incision wound is a wound that is intentionally made by a clean-cut using a sharp object. Betel leaf is a natural ingredient that helps the wound healing process because it has active ingredients such as saponins, tannins, flavonoids, essential oils, and alkaloids. The study aimed to determine the effect of betel leaf extract on the healing process of incision wounds in white rats. This study uses a true experimental research design conducted on white rats. Samples were taken by random sampling and divided into four groups, namely control group (KK) (n = 6), treatment group with a dose of 10% (P1) (n = 6), treatment group with a dose of 15% (P2) (n = 6) and treatment group with a dose of 20% (P3) ( n = 6). The mean of wound’s length in KK=0.78 cm, P1=0.67 cm, P2=0.57 cm, and P3=0.15. Based on the Kruskal Wallis test, p value=0.000(α0.05), there is a significant difference in the wound healing process between the control and treatment groups. Betel leaf contains active substances, namely flavonoids, alkaloids, saponins, tannins, and essential oils. The active substance causes the wound’s edges to close faster, so the wound heals faster.
Analysis of Ovarian Cancer Risk Factor : A Systematic Review
Authors: Nurhidayah Ida , Widiasih Restuning , Ermiati Ermiati
Published: December 2023

Ovarian cancer risk factors are health problems that risk women's survival. Health workers and women must recognize the risk factors that can lead to ovarian cancer as early prevention. This systematic review aimed to analyze various risk factors for ovarian cancer. The systematic review used 4 databases, Proquest, Pubmed, Willey, and Ebsco, with the keywords ovarian cancer AND risk factors AND determinant factors OR predisposition factors AND incident OR prevalence. Inclusion criteria include relevant articles according to the topic, type of quantitative research, no year limit specified, and English. The initial number of searches obtained was 3,507 articles. The PRISMA usage flow and JBI tools 15 articles were reviewed. The study's results identified risk factors for ovarian cancer: reproductive factors, lifestyle, family history, benign ovarian tumors, endometriosis, and endometriomas. Reproductive factors are the factors most associated with the occurrence of ovarian cancer. Reproductive factors covered pain during menstruation, menstrual age, delayed menopause, infertility, use of fertility drugs, parous women, childbearing age, miscarriage, induced abortion, not breastfeeding, and intrauterine contraceptives, use of exogenous hormones, and use of hormone supplements.
The Effectiveness of Internet Addiction Mobile Application on Sleep Quality of Internet-Addicted Students
Authors: Rinjani Santi , Vitniawati Vina , Jundiah Raden Siti
Published: December 2023

ABSTRACTExcessive internet use causes addiction leading to obsessive-compulsive behavior, depression, anxiety, juvenile delinquency, and sleep disorders. Poor sleep quality will reduce the ability to think, increase the risk of accidents, hormonal metabolism disorders during puberty and menstruation, excessive fatigue during the day, and impaired activities in work, school, and social functions. Internet addiction therapy is often carried out after complaints of severe symptoms such as social isolation, depression, and the risk of suicide. Patients must be hospitalized, which takes a long time and cost. Thus, developments are carried out to overcome the problem of internet addiction by preventing, screening, and intervening in internet addiction in a practical, effective, safe, and economical way using mobile applications. This study aimed to identify the effectiveness of internet-addiction mobile applications on internet-addicted students' sleep quality. A quasi-experimental using non-equivalent control group design with pre-test and post-test. The research instrument used was the Internet Addiction Test (IAT) and the Pittsburgh Sleep Quality Index (PSQI). This study used a consecutive sampling of 46 people for the intervention and control groups. Data were analyzed using the McNemar test. Internet-Addiction Mobile Application significantly improved sleep quality for students who experienced internet addiction (60,9%) experienced good sleep quality. Furthermore, Internet-Addiction Mobile Application can significantly reduce internet addiction (p-value = 0.04). Internet-Addiction Mobile Application effectively improves students' sleep quality who experience internet addiction. This information can be used as data to prevent and intervene in sleep quality problems in people with internet addiction.
Utilization of treated water for building construction: A case study in Egypt
Authors: Mohammed-Hassanien Amera Marey , Badawy Mohamed M. , El-Romy Ahmed , Adel Sherihan
Published: December 2023

Due to rising living standards and population growth, saving fresh water will be a significant problem for the next generation. The Government is indirectly impacted by a significant financial burden due to the current usage of treated wastewater, in all of Egypt's districts. As a case study, Egypt's new administrative capital was chosen, given that it is today one of the most important cities and that its planning was predicated on making it a smart, sustainable city. The goal of the study was to develop methods for replacing potable water in the manufacture of concrete with tertiary-treated wastewater; however, used for concrete mixing or curing after concrete hardening. Property assessments of the fresh and hardened concrete were conducted, to ascertain the best water quality that can be used without compromising the quality or durability of the concrete. ; The results of this paper will serve as a guide for decision-makers looking to decrease costs and increase sustainability by using treated wastewater in making sustainable concrete for buildings, especially in recent decades, rising construction material usage has generated considerable environmental difficulties, particularly in the production of Ordinary Portland cement (OPC).
Clinical significance of determining neutrophil extracellular traps in women with oncogynecological neoplasms
Authors: Aslanova Z. D. , Khizroeva J. Kh. , Solopova A. G. , Solodkiy V. A. , Vorobev A. V. , Blinov D. V. , Aslanova M. D. , Nakaidze I. A. , Gris J.-C. , Elalamy I. , Makatsariya A. D.
Published: December 2023

The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community. NETs play a key role in inflammation and infection exploiting effector functions such as degranulation, phagocytosis as well as production of reactive oxygen species (ROS). NETs play a crucial role in defense against systemic infections. Additionally NETs involved in inflammation, and in the pathogenesis of non-infectious diseases, such as autoimmune diseases and cancer.
Pathogenic and Non-Pathogenic Microbial Presence in Ventilator Associated Pneumonia Patients in Intensive Care Unit and Safety Protocols Under Surveillance of Healthcare Provider: A Research Study
Authors: Sana Hashmi  , Nimer Alsabeelah  , Faleh Al-Harbi  , Umama Yezdani  , Norah Abdullah Saleh Almoutiri  , Talal Jahaz Thabbat Almutairi  , Sultan Fraih Alshammri  , Mohammad Rashid  , Abdullah Ghurman Alamri  , Khalid Saadi Alsuhaymi  , Hatim Saadi Alsuhaymi
Published: December 2023

Ventilator-associated pneumonia (VAP) is a common hospital-acquired infection that is associated with longer stays in intensive care units (ICUs) and under mechanical ventilation for more than 48 hours. This article explores the prevalence and impact of VAP on mortality and morbidity, emphasizing the microbial associations involved in hospital-acquired infections. Various infections, including Lung infections, surgical site infections, sepsis, and urinary tract infections, are discussed, along with their associated microorganisms. Diagnostic criteria for VAP and related infections are outlined, highlighting the importance of microbiological testing for accurate diagnosis. The underlying factors for VAP acquisition in ICU patients are identified, and prompt antibiotic initiation is emphasized as a critical first-line defense against VAP. In this study, we have populated data from 100 ICU patients, among which 45 were suffering from VAP. It was found that female patients (57.40%) were more affected than male patients (30.43%). The decreasing PaO2 level was seen to be the early sign of infection. It was found that the time of ventilation was the major factor influencing the VAP. The most common organism causing infection in our study was found to be Staphylococcus Aureus (45.1%). The prognosis of early-onset VAP was 35.55% while compared to Late-onset VAP 64.44%. When compared to VAP and Non-VAP patients there was not very huge difference with 55% and 45% respectively. The other factor was age and position. Implementation of Prevention strategies, such as protective environments and HEPA filtration systems, is proposed to reduce VAP incidence. Proper diagnosis, treatment, and prevention are crucial to combatting VAP and enhancing patient outcomes in hospital settings.
A Novel Approach and Implementation Concept For A Nanosatellite Backup on-Board Computer
Authors: H Venkatesh Kumar  , Rohith S  , Kasetty Ram Babu  , Chikkarangaiah T R  , Supreeth S
Published: December 2023

STUDSAT-2 (STUDENT SATellite-2) is a one-of-a-kind satellite technology project undertaken by Indian undergraduate students. The aim of this project is to demonstrate the On-Board Computer's redundancy (OBC). The OBC subsystem is one of the many subsystems that make up the STUDSAT-2 satellite system. It is critical to the satellite's operation. Even a minor malfunction in this system could lead to the mission's complete failure. As a result, OBC redundancy management is required to overcome this. As a result, the proposed model of Backup On-Board Computer for STUDSAT-2 was planned and built by incorporating redundancy in both software and hardware, thus increasing the OBC's reliability.
Determining the Prevalence of Nosocomial Infections in Lordegan Shohada Hospital, 21 March 2017 to 19 March 2020
Authors: Sadeq Hosseinpour  , Elahe Seidaie Golsefidi  , Mohsen Saeedi abo-s-haghi  , Tahmineh Tahmasbi  , Afshin Yarmohammadi Samani  , Gelareh Kiani harchegani  , Somayyeh babamir Satehi  , Hossein Maghamimanesh
Published: December 2023

Background and Objectives: Currently, Nosocomial Infections (NIs) or Health Care Worker Infections (HCWIs) have become one of the important health issues in many countries of the world, including Iran. This study was conducted to determine Prevalence of NIs in Shahada Lordegan Hospital from March 21, 2017 to March 19, 2020.  Methods:  In this cross-sectional descriptive study, the files of 45,830 patients who were at risk of NIs (cases that were hospitalized for at least 48 hours) were examined and cases of NIs were diagnosed based on references (definitions of the US Center for Communicable Disease Control and the surveillance system NIs of this type of infections) and the case finding form of NIs and then registered in the hospital infection care system. All stages of data analysis were performed in the hospital infection care system software version 2-2-4. Results: The overall incidence of NIs was equal to 0.6%, the incidence in men was 54.9% and in women 45.1%. The most common type of NIs in this center was surgical site infection (SSI) (0.2%), non-ventilation- associated pneumonia (0.17%) and ventilation-Associated (VAE) event (0.16%), and there are the highest rate of infections a hospital in intensive care. Conclusions NIs are a major problem for patients hospitalized in the ICU in In this center. Furthermore, according to this review and other studies conducted in Iran, It seems that the rate or NIs in is much fewer than Global rate of NIs, and the probably irrational use of antibiotics and as a result hinding these types of infections as well as underreporting are important factors of this problem.
Acute Subdural Hematoma Management in the Emergency Department
Authors: Fahad Bahaidarah  , Afnan Adel Ashqa  , Al Khonaizi  , Ali Nezar M  , Salman  , Abdulmajeed Saleh O  , Rakan Saleh Alzahrani  , Alghamdi  , Khalid Hussain O  , Alghamdi  , Ibrahim Ahmed S  , Al Shokan Moustafa Abdullah  , Albadr Mohammed Ahmed A  , Alnemari, Arwa Sultan D  , Sultan Fahad Alharbi  , Almoumen, Faisal Abdullah A  , Alharthi  , Afrah Hamoud H
Published: December 2023

Acute subdural hematoma (ASDH) is a serious and potentially life-threatening condition that requires prompt and effective management in the emergency department (ED). This review article aims to provide an overview of the current evidence-based management strategies for ASDH in the ED setting. The article begins by discussing the pathophysiology of ASDH, emphasizing the rapid accumulation of blood between the dura mater and the arachnoid membrane following a traumatic brain injury. This can lead to increased intracranial pressure and potentially fatal brain herniation if not promptly addressed. The review then outlines the initial assessment and resuscitation of patients with suspected ASDH in the ED. The article then delves into the specific management strategies for ASDH in the ED, including the role of neurosurgical consultation, and the potential need for emergent surgical intervention to evacuate the hematoma and relieve pressure on the brain. In conclusion, this review article provides a comprehensive overview of the current evidence-based management of ASDH in the ED, emphasizing the importance of prompt recognition, accurate diagnosis, and timely intervention to optimize patient outcomes.
Social and ethical component of genetic technologies
Authors: Yakovleva Irina V. , Gaidukova Sofya E. , Kamionskaya Anastasiya M.
Published: December 2023

The technologies of genome editing and synthetic biology are becoming more and more accessible today and, in combination with the application of artificial intelligence in biotechnology, especially powerful. A feature of today’s stage is the rapidly changing landscape of engineering biological systems, which requires revision and updating of the biosafety framework. The proposed new oversight measures are as follows: а) screening for DNA synthesis orders and sequences of concern; b) environmental metagenome sequencing to search for synthetic organisms [1]. At the same time, DNA ‘printers’ are appeared on the market today, that blurs the boundaries of access to synthetic DNA. It is significant that no government currently requires screening or regulates it, and this system works on a benevolent basis. Additionally environmental surveillance requires for a long time to define base line. With the new scale of human activity, new social risks also arise: new forms of discrimination and inequality, confidentiality of personal data in biotechnology projects, multiplication of biotechnology and artificial intelligence risks.
Thus, the idea of “responsible researches and innovation” (RRI) [2], and trend to address safety early at the concept stage — “Safe by design” have come into the focus. A number of RRI principles can be formulated at the proof concept stage for a genome- edited project: benefits for most citizens; transparency, the public comment cycle prior to the start of the experiments; responsibility, precautions, liability; justice, redress; well-being, social good.
Obtaining of transgenic barrelclover plants (Medicago truncatula) producing chicken interferon gamma for veterinary use
Authors: Okulova Elena S. , Burlakovskiy Mikhail S. , Padkina Marina V. , Lutova Ludmila A.
Published: December 2023

At the Laboratory of Plant Genetic and Cellular Engineering, Department of Genetics and Biotechnology, St. Petersburg State University, five transgenic Medicago truncatula plants were obtained through Agrobacterium-mediated transformation, carrying one of the variants of the heterologous chicken interferon-gamma gene under the control of the constitutive 35S CaMV promoter. Among these, one plant harbored an unmodified gene insertion, while four had a modified gene with a deletion at the protease recognition site, providing resistance to proteolytic degradation.
We demonstrate the application of the SWPOP-PCR “genome walking” method to determine the integration sites of T-DNA into the plant genome, identify the number of insertion copies and their orientation. Analysis of the obtained sequences revealed that only one plant exhibited a single T-DNA insertion, which represents the most optimal structure for stable expression.
Upon self-pollination of T0 plants, 39 offspring were obtained and subjected to testing for the presence and expression of the transgene. Among them, six homozygous plants were identified using molecular methods. Quantitative assessment of transgene expression levels showed significant differences among representatives of different lines and among the offspring derived from a single transformed plant. Among the T1 and T2 progeny, the presence of the heterologous interferon protein in plant tissues was confirmed through Western blot analysis.
The engineered barrelclover plants hold potential as bioreactors for the production of chicken interferon-gamma for veterinary applications. The use of an edible plant allows eliminating protein extraction and purification procedures, thereby resulting in a noteworthy reduction in production expenses of up to 80%.
Effect of biotin starvation on gene expression in industrially significant yeast Komagataella phaffii
Authors: Makeeva Anastasia S. , Sidorin Anton V. , Ishtuganova Valeriia V. , Padkina Marina V. , Rumyantsev Andrei M.
Published: December 2023

Komagataella phaffii(Pichia pastoris) is known to be an excellent producer of recombinant proteins for industrial and research purposes. Protein synthesis improvement in this yeast includes selection of optimal cultivation parameters [1, 2]. Therefore, much attention is paid to the influence of media components on physiology of this yeast [3–5].
One of the essential media components is biotin. In yeast cells it plays a crucial role as a cofactor of enzymes, providing carboxylation reactions in lipo-, gluconeogenesis, and nitrogen metabolism.K. phaffiiis biotin auxotrophic organism unable to synthesize this vitaminde novo. Thus, it necessarily requires adding of biotin in the media.
In this study, we analyzed the effect of biotin starvation on gene expression inK. phaffiicells during its growth on methanol- and glycerin-containing media. These carbon sources are the most commonly used in standard protocols for recombinant protein biosynthesis inK. phaffii.
It was shown, that biotin starvation cell response significantly depends on carbon source. In glycerol-containing media biotin deficiency enhanced transcription of genes involved in biotin and thiamine metabolism, glyoxylate cycle, synthesis of acetyl-CoA in cytoplasm and its carnitine-mediated transport into mitochondria. Genes involved in biosynthesis of lipids and glucose were repressed in media with glycerol. In methanol-containing media the biotin deficiency effect was more pronounced and led to repression of numerous genes involved in protein and amino acids synthesis and activation of cell response to oxidative stress.
The obtained results are thought to be important for optimizing the culture conditions in theK. phaffiiexpression systems.
New naturally transgenic crop
Authors: Shaposhnikov Anton D. , Matveeva Tatiana V.
Published: December 2023

Horizontal gene transfer from agrobacteria to plants turned out to be a much more widespread phenomenon than previously thought. In the first it was established in 2019 due to the application of bioinformatic methods and databases, then about 30 species of naturally transgenic plants were discovered [1]. The deposition of new nucleotide sequences of various plant species makes it possible to periodically update the list of naturally GMOs. Analysis of genomic and transcriptomic databases in 2023 revealed more than 50 new naturally transgenic plants and, thus, more than 100 species of nGMOs are currently known. And the share of naturally transgenic plants in relation to deposited species of terrestrial dicotyledonous plants is about 7%. Interestingly, this indicator retains its value regardless of the change in the number of organisms in the studied databases [2].
Among the discovered new nGMOs there are species that have been cultivated by humans since ancient times and are important agricultural crops. Fruit crops include the following species of nGMOs: carambola (Averrhoa carambola L.), persimmon (Diospyros kaki Thunb.), wasabi (Eutrema japonicum (Miq.) Koidz.), raspberry (Rubus idaeus L.), Luffa acutangula (L.) Roxb. There are also many medicinal, ornamental and oilseed species among the naturally transgenic plants. Further study of these species would make it possible to establish what role horizontal gene transfer played in the appearance of traits in plants that were selected by humans.
The obtained data can be further used to study the molecular evolution and the role of transgenes in naturally transgenic plants.
Natural GMOs inside the genus Arachis L.
Authors: Bogomaz Olesja D. , Bemova Victoria D. , Matveeva Tatiana V.
Published: December 2023

Cultivated peanut is an allotetraploid species that received the A and B genomes from Arachis duranensis and A. ipaensis. Homologs of the agrobacterial cucumopine synthase gene were previously found in both genomes as a result of horizontal transfer [1]. These sequences are found both in ancestral species and in cultivated peanuts. In addition to them, natural GMOs are A. monticola and A. stenosperma. How widespread natural GMOs are within the genus Arachis is currently unknown. The aim of our study was to search for natural GMOs within the genus Arachis and to analyze the polymorphism of natural transgenes out the studied species.
METHODS: Gene sequencing for various Arachis species was determined using the bwa [2], GATK [3] and samtools [4] packages based on NGS data aggregated in the SRA NCBI database.
RESULTS: We have found homologues of the cucumopine synthase gene in the genomes of A. appressipila, A. batizocoi, A. cardenasii, A. correntina, A. diogoi, A. duranensis, A. glandulifera, A. helodes, A. hoehnei, A. ipaensis, A. macedoi, A. magna, A. monticola, A. paraguariensis, A. pintoi, A. pusilla, A. rigonii, A. stenophylla, A. stenosperma, A. trinitensis, A. valida, A. villosa, and also characterized the intraspecific variability of the gene in cultivated peanuts. In 16 of the 22 species studied, the gene is full-length. The report will consider the possibility of using the cucumopine synthase gene in peanut phylogenetic studies.
CONCLUSION: The list of species of natural GMOs within the genus Arachis today includes 23 species.