bluuebunny/crossref_metadata_2025 huggingface dataset:
An approach to managing the stability parameters of complex infocommunication systems under destructive influences
Authors: Yakushenko S.A. , Dvornikov S.V.
Published: November 2023

The paper considers the approach to managing the stability parameters of complex infocommunication systems based on the structural-parametric method of analysis and synthesis of the state of opposing systems. An algorithm for controlling the parameters of the system's resistance to destructive influences with a priori uncertainty of the intentions of the impact is proposed. The solution of the problem of increasing the stability of the infocommunication system in the dynamics of the development of an antagonistic conflict using a system of Kolmogorov differential equations and the optimal distribution of its protective resource is obtained. The proposed approach, the developed algorithm and the results obtained can be used to justify the requirements for stability parameters and their implementation in infocommunication systems as part of the transition to methods of increasing its stability based on artificial intelligence.
Characteristic calculations of antennas for communication and retransmission placed on aircraft and helicopter unmanned aerial vehicles
Authors: Buzov A.L. , Buzova M.A. , Kolchugin Yu.I. , Kotkov K.V.
Published: November 2023

The issues of increasing the communication range when organizing data transfer between two remote sites are especially important and very relevant. An increase in the communication range can be achieved by increasing the height of the antennas. One of the effective technical solutions that allow placing antennas and radio stations at high altitude in the required place is the use of modern unmanned aerial vehicles (UAV). Target. Calculations and studies of the characteristics of antennas placed on UAV of various types. The results of calculations of the energy and spatial characteristics of three types of antennas installed on UAV of various types are obtained: asymmetric whip antenna; a low-profile antenna consisting of three PIFA emitters; an annular antenna array consisting of 6 asymmetric Uda-Yagi antennas. It is shown that each of the solutions has its own advantages and disadvantages and its own scope. Based on the obtained results of calculating the characteristics of antennas, the developers of the corresponding communication systems can make a reasonable choice of the types of antennas used, depending on the requirements for the systems as a whole.
Clinical Evaluation of Pippalyadi Avapeeda Nasya, Elakanadi Kashaya and Vyoshadi Ghrita in Chronic Rhinosinusitis: Case Series
Authors: Kartha Sreelakshmi S. , Ashwini B. N. , Sivabalaji K.
Published: November 2023

Introduction: Chronic Rhino Sinusitis (CRS) is an inflammatory disease of the nose and sinuses with clinical features such as nasal blockage, nasal discharge and hyposmia. Current treatment modalities are antibiotics, corticosteroids and surgical interventions but the recurrent rate is high. In classics, dushtaprathisyaya features are similar to chronic rhinosinusitis. Materials and Methods: To analyze the effect of pippalyadi avapeeda nasya, elakanadi kashaya and vyoshadi ghrita in reducing the symptoms of chronic rhino sinusitis using nasal signs and symptom score, anterior rhinoscopy, X-ray Para Nasal Sinus (PNS) Waters view and nasal endoscopy. The study discusses the Ayurvedic intervention of 30 cases diagnosed as CRS. Pachana - deepana with astachoorna, snehapana with vyoshadi ghrita and virechana with nimbamritadi eranda taila for kayashodhana followed by shira shodhana with pippalyadi avapeeda nasya. Orally Elakanadi kashaya and vyoshadi ghrita was administered. Results and Discussion: Combined use of sodhana and samana aushadhi showed significant reduction in nasal obstruction, nasal discharge and hyposmia with an improvement of 100, 100 and 56.66 % respectively. Statistical analyses were performed with SPSS software and are clinically significant with p < 0.0001. Conclusion: A combination of kayasodhana and sirasodhana is effective in improving subjective symptoms like nasal blockage, nasal discharge and hyposmia which was evident with anterior rhinoscopy, endoscopy and X-ray PNS Waters view.
Evaluation of Antioxidant and Anti-diabetic Activity of Stem Bark of Ziziphus jujuba (L.) Gaertn
Authors: Shanthi S. , Latha S. , Karthikeyan G. , Jeeva P. , Janani A. , Karthick K.
Published: November 2023

Diabetes Mellitus (DM), a significant metabolic disorder that increases mortality and morbidity, affects people all over the world. Recently, many individuals are exploring CAM treatment that may have fewer side effects due to the prominent side effects of allopathic medications. Ziziphus jujuba (L.) Gaertn. (Rhamnaceae) stem bark has been a vital part of the conventional system of medicine for the management of diabetes, inflammation, wounds, fever, asthma and liver disorders. In spite of its pharmacological significance, Ziziphus jujuba stem bark lacks scientific evidence of its antidiabetic and antioxidant potential. Hence, an attempt has been made to evaluate the anti-diabetic effect of the stem bark of Ziziphus jujuba using alpha-amylase inhibition assay. In this research work, we further investigated the antioxidant activity of the Ziziphus jujuba using DPPH and Nitric oxide radical scavenging assay. The Chloroform (CEZJ), ethyl acetate (EAZJ) and Ethanol (EEZJ) extracts of Ziziphus jujuba stem bark were used in the study. In the DPPH radical scavenging assay, EEZJ had an IC50 value of 117.1 µg/ml, however, the value for the nitric oxide scavenging assay was 64.65 µg/ml. The Ziziphus jujuba was additionally examined for its in-vitro antidiabetic potential using an alpha-amylase inhibition assay, and it was discovered to possess a considerable percentage of alpha-amylase inhibition. The IC50 of EEZJ was found to be 34.68 µg/ml. These results imply that the Ziziphus jujuba possesses considerable antioxidant and anti-diabetic properties. To thoroughly establish the anti-diabetic potential of Ziziphus jujuba, additional in vitro experiments utilizing cell lines and other enzymes may be conducted.
In Silico Computational Analysis of Citrus aurantium of Thurunji manapagu in Inhibiting the Receptor Target of Angiotensin-converting Enzyme Against Uratha Pitha Vatham (Hypertension)
Authors: Sudalaimani Radha , Thangapandiyan Swathi , Andi Mariappan , Udayar Sivakumar Shantiarappa , Ramasamy Meenakumari
Published: November 2023

Citrus aurantium (Thurunji) is a tree cultivated in various parts of the world. The fruit pulp is used to make juices, marmalade and pickles. It is commonly used by tribes to treat digestive disorders, constipation, heaviness in the chest, prolapse of the uterus, anorexia, chest pain, cold, and cough. In the Siddha system of medicine, Citrus aurantium fruit pulp is used to prepare a formulation, syrup in consistency named Thurunji manapaagu indicated for diseases due to deranged pitha humor. According to the Siddha system of medicine Hypertension termed Uratha Pitha Vatham is an ailment that occurs due to an elevated pitham. Considering the facts an attempt of in silico docking study was done with the selected phytochemicals such as Linalool, Apigenin, Ichangin, Kaempferol, Luteolin, Limonin, Limonene, Myrcene, Diosmetin and Tangeretin of Citrus aurantium against Angiotensin Converting Enzyme (ACE) and the results are detailed in this article.
Effect of Abhaya Ghana Vati along with Pathya Aaahara Vihara (Diet and Lifestyle Regime) on Patients of Diabesity – A Single Arm Clinical Trial
Authors: Joglekar Aishwarya Ashish , Vyas Mahesh , Bhojani Meera K. , Kumar Anil
Published: November 2023

Introduction: Ayurveda beautifully amalgamates herbal drugs and lifestyle modifications in the management of various diseases and lifestyle disorders. Diabesity is one condition representing the two most prevalent chronic non-communicable diseases, i.e., Diabetes and Obesity According to Ayurveda, both conditions are referred to as Prameha and Sthoulya, respectively. Both the conditions are Santarpanottha Vyadhi (diseases arising from excessive and improper nutrition), having the common vitiation of Kapha Dosha, Meda Dhatu and Ama and similar lines of treatment. Haritaki or Abhaya (Terminalia chebula) is a herb that has the potential to manage both diabetes and obesity. The present study focuses on the efficacy of Abhaya Ghana Vati as a single drug regime coupled with Pathya Aahara Vihara (diet and lifestyle regime) in the management of diabesity. Methods: Abhaya Ghana Vati along with Pathya Aahara Vihara (diet and lifestyle regime), was administered in 41 patients for three months, including follow-up. The patients were assessed for the effect of the intervention on the subjective and objective criteria. Results: The intervention showed significant improvement in most of the parameters of outcome measures like BMI (27% improvement, p<0.001), Waist Hip Ratio (p<0.002), Abdominal Girth Circumference (p<0.001), Chest Girth circumference (p<0.001), Waist circumference (p<0.001). The Fasting Blood Sugar (FBS) levels declined significantly from the mean (187.4 to 168.9, p<0.048), and PPBS reduced from the mean (260 to 230.4, p<0.011), which was statistically significant. However, HbA1c declined very marginally from the mean of 8.32 to 8.23 (p<0.71). Effect of treatment on subjective parameters like Apatarpana Lakshana, Dhatusamya Lakshana and Quality of Life parameters showed significant change. Conclusions: Administration of Abhaya Ghana Vati and Pathya Aahara Vihara are beneficial in patients of diabesity.
Development and Greenness Assessment of Analytical Quality by Design Optimised Eco-friendly UV Spectrophotometric Methods for Analysis of Two Natural Antioxidants in Pure and Formulation
Authors: Jonnalagadda Ramya , Rathinam Seetharaman , Chandrasekar Vinodhini
Published: November 2023

Utilizing analytical quality by design and green analytical chemistry principles, the present work introduces simple, robust, and environmentally benign UV methods. Two separate spectrophotometric methods were developed for the estimation of Silybin and Curcumin, where solvent, scan speed, and sampling interval are the estimated critical parameters. The detection was carried out at absorption maxima of 288nm for Silybin and 419nm for Curcumin with ethanol. To determine the critical method variables, a risk assessment was carried out using an Ishikawa diagram. Developed spectrophotometric methods were validated according to the International Council for Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use Q2 (R1) guidelines. The proposed methods showed good predictability and robustness. The new methodologies were found to be green according to the analytical greenness metric approach and software, the green analytical procedure index, and analytical eco-scale tools in comparison to the existing methods.
Hepatoprotective Efficacy of Phytochemically Screened Nyctanthes arbor-tristis
Authors: Sharma Ajay , Kewatkar Shailesh , Dhumal Jeevan S. , Jain Gaurav , Jagwani Akanksha , Joshi Amit , Garg Har Goving
Published: November 2023

The Oleaceae plant Nyctanthes arbor-tristis Linnaeus is used in Ayurveda medicine as a laxative, diuretic, and for the treatment of a variety of painful conditions including sciatica, arthritis, and fever. This study aimed to determine whether or not extracts of Nyctanthes arbor-tristis leaves, either in alcohol or water, might prevent liver damage caused by carbon tetrachloride in rats. Administration of alcoholic and aqueous extracts of the leaves of Nyctanthes arbor-tristis protects the liver against the toxicity of carbon tetrachloride by lowering the high levels of serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase, and serum bilirubin (total and direct). Both the alcoholic and aqueous extracts demonstrated hepatoprotective efficacy at a dosage of 500 mg/kg body weight by significantly reducing the high levels of biochemical markers. Liver histopathology studies corroborated the extracts’ potential to restore damaged hepatocytes.
Siddha Therapeutic Approach to Diabetic Nephropathy – A Review
Authors: Parvathy P. , Lekha G. S. , Aparna S. , Kanagarajan A.
Published: November 2023

Diabetic Nephropathy (DN) is a severe kidney illness that presents with proteinuria, enlarged glomeruli, reduction in the process of glomerular filtration, and fibrosis of the kidneys. Approximately one-third of all instances of diabetes globally are brought to diabetic nephropathy, a common cause of end-stage kidney disease. In Siddha’s literature, the complications of Diabetes mellitus were expressed as ten Avathaigal in the Neerizhivu noi chapter. The feature of Avathaigal 1 to 7 depicts some of the clinical outcomes of Diabetic Nephropathy. The manifestation of clinical features in final stage Diabetic Nephropathy includes oliguria, fatigue, anorexia, nausea, vomiting, itching and dryness of skin, drowsiness, numbness and swelling in the limbs, muscle twitching or cramps, bone pain, breathlessness, increased thirst, sleep disturbance, and sexual problems. Oxidative stress is the standard mechanism involved in developing diabetic kidney disease. Most of the Siddha medicines used for managing diabetic Nephropathy are herbal formulations, and they protect against damage to the renal tubules due to their significant antioxidant property. This review summarizes the pathophysiology of Diabetic Nephropathy and the evidence for using Siddha herbal formulations to treat diabetic Nephropathy. For treating early-stage diabetic Nephropathy, Siddha practices primarily emphasize using herbal formulations; however, yoga therapy, diet, and other exercises are also included in Siddha treatment modalities.
Simultaneous Estimation of Eugenol and Scopoletin from the in House Avipattikar Churna by RP-HPLC Method and Estimation of Scopoletin from Different Extracts of Jalap
Authors: Shah Priya , Zaveri Maitreyi
Published: November 2023

Background: Although standardising polyherbal medicine requires immediate attention, it is a tedious undertaking. Phytochemical profiling is a particularly useful tool for assessing the quality and effectiveness of polyherbal medicines, among various methods used for standardization. The proposal aimed to develop a precise RP-HPLC method for simultaneous estimation of eugenol and scopoletin in in-house Avipattikar churna. This method was also used to estimate scopoletin in various extracts of Ipomoea turpethum. Methods: The phytomarkers in Avipattikar churna, hydroalcoholic and alcoholic extracts of Jalap were estimated by RP-HPLC system. In this setup, RP-ODS C8 column was employed with methanol: water (30:70 v/v, 0.1% formic acid) at 1 ml/min for 0-10 minutes, and then with methanol: water (60:40 v/v) at 0.8 ml/min for 10.01-25 minutes. Detection was done at 280 nm for eugenol and 366 nm for scopoletin using a UV/VIS detector. The method was validated by performing validation parameters as per ICH guidelines. Results: The linearity of eugenol and scopoletin was performed, with correlation coefficients of 0.999 and 0.9969 respectively. In repeatability, % RSD was observed as 0.856 and 0.909 for eugenol and scopoletin correspondingly. The LOD (detection limit) of eugenol was 0.67 μg/mL and of scopoletin was 1.39 μg/mL. While LOQ (quantification limit) of eugenol was found as 2.04 μg/mL and 4.03 μg/mL for scopoletin. The % recovery was ranging from 102.96 - 100.45 % for eugenol and from 102.65 - 101.3 %w/w for scopoletin, after adding a pre-quantified amount (20 μg/mL) in the different concentrations of the standards. The eugenol and scopoletin were estimated 0.1366 %w/w and 0.0465 %w/w respectively in Avipattikar churna. The hydro alcoholic extract of Jalap showed presence of more scopoletin than in the alcoholic extract. Conclusion: The validated process is established as accurate, consistent and precise which results as a better standardization drive for Ayurvedic dosage forms.
ENTRE DEVOÇÃO E EXPRESSÃO POPULAR: UM ESTUDO SOBRE O PATRIMÔNIO NO PÁTIO DE SÃO PEDRO EM RECIFE-PE
Authors: Nascimento Neto Josebias Costa do , Moura Filha Maria Berthilde de Barros Lima e , Valadares Pedro Henrique Cabral , Silva Ana Lúcia Francisca da
Published: November 2023

Este estudo se concentra no contexto do patrimônio cultural, com o objetivo de fornecer percepções sobre a incorporação de manifestações populares em ambientes tradicionalmente hieráticos, tendo como objeto empírico da pesquisa o pátio de São Pedro, no Recife-PE. Com o objetivo de compreender em que medida essas atividades culturais atuam como agentes fomentadores da preservação desse local, essa pesquisa se debruça sobre a história, festividades e os usos do pátio ao longo de sua existência. Como resultado obtido neste trabalho, elenca-se as transformações de uso e ocupação do solo através das mudanças e permanências, aqui mostradas desde 1950 até os dias atuais, como fator determinante para a sustentabilidade futura deste local histórico. O pátio enquanto um lugar histórico e de memória, além de servir como palco para manifestação da cultura pernambucana, luta contra a ameaça do apagamento proposto pelo elevado percentual de imóveis vazios ou subutilizados em seu entorno; portanto demanda uma ação conjunta entre as esferas competentes para que haja uma efetiva e cautelosa intervenção com o propósito de perenizar essa faceta histórica da identidade da cidade do Recife.
Identification and dynamics prediction of a plane vortex structure based on a mathematical model of a point vortices system
Authors:   Southern Federal University, Govorukhin Vasiliy
Published: November 2023

The aim of the article is developing and analyse an algorithmic method for solution finding of one inverse problem of 2d vortex fluid dynamics. It is identification and prediction of the flow structure evolution of the based on the data on fluid velocity vectors in a set of reference points. Theoretical analysis of convergence and adequacy of the method is difficult due to the ill-posedness typical of inverse problems, these issues studied experimentally. Methods. The proposed method uses a mathematical model of a point vortex dynamics system for identification and prediction flow structures. The parameters of the model system are found by minimising the functional that evaluates the closeness of the original and model vectors fields at the reference points. The prediction of the vortex structure dynamics is based on the solution of the Cauchy problem for a system of ordinary differential equations with the parameters found in the first stage. Results. As a result of the calculations, we found it out: the algorithm converges to the desired minimum from a wide range of initial approximations; the algorithm converges in all cases when the identified structure consists of sufficiently distant vortices; the forecast of the development of the current gives good results with a steady flow; if the above conditions are violated, the part of successful calculations decreases, false identification and an erroneous forecast may occur; with the convergence of the method, the coordinates and circulation of the eddies of the model system are close to the characteristics of the eddies of the test configurations; the structures of the streamlines of the flows are topologically equivalent; convergence depends more on location than on the number of vectors used for identification. Conclusion. An algorithm for solving the problem of identifying and the evolution forecast of a 2d vortex flow structure is proposed when the fluid velocity vectors in a finite set of reference points are known. The method showed its high efficiency when using from 40 to 200 reference points. The results of the study make it possible to recommend the proposed algorithm for identifying flat vortex structures, which consist of vortices separated from each other.
Excitation by shot circuited coaxial transducer of magnetostatic modes in rectangular yttrium iron garnet film
Authors:   Southern Federal University, Babichev Rudolf
Published: November 2023

The purpose of this work is the study of design of new short-circuited coaxial transducer with thin linear jumper, that circuits on one side of the grounded coaxial cylinder, located above the rectangular iron-yttrium garnet (YIG) film, in homogeneous constant magnetic field with rectangular film along its length or width. The thin linear jumper is directed parallel to the width of the YIG film. Methods. In the CST Microwave Studio environment, an electrodynamic analysis of the model was carried out using the finite element method. To study the efficiency of modes excitation in a ferrite film at different distances between the coaxial transducer and the surface of the YIG film, the frequency dependences of the inverse losses S11 of the model were calculated. Results. 1. The identification of modes in a homogeneous static magnetic field H , directed parallel to the plane of a rectangular YIG film along its width (z-axis) was carried out. 2. The identification of modes in a homogeneous static magnetic field H directed parallel to the plane of the rectangular YIG film along its length (y-axis) was carried out. 3. A comparison of modes spectra was made at H, directed parallel to the plane of the YIG film along its width (z-axis) and length (y-axis). Conclusion. In this paper short-circuited transducer with a thin linear jumper, circuited on one side of the grounded coaxial cylinder, is investigated. By the electrodynamic method distributions of high-frequency magnetic field of the excited magnetostatic modes were calculated and their identification was carried out for two directions of homogeneous static magnetic field H: along width and along length of rectangular YIG film. The dependence of number of excited modes on the distance between a short-circuited transducer and rectangular YIG was also studied. A comparison of modes spectra is carried out at H, directed parallel to the plane of the YIG film along its width and length. With this rotation of vector, the band of effectively excitable modes shifts from 4.6...4.9 GHz to 4.5...4.75 GHz. However, the excitation of these modes in the case of the vector H, directed along the width of YIG film (z-axis), is much more effective in the band 4.65...4.9 GHz than in the case when this vector is directed along the length of YIG film (y-axis). At the same time, excitation of these modes in the case of the vector H, directed along the length of YIG film (y-axis) is effective in the band 4.4...4.6 GHz.
Epidemiology of zygomaticomaxillary complex fracture in oral and maxillofacial trauma patients
Authors: Ghasemi Tayebeh , Khazaei Amir Hossein , Teymoorpoor Fatemeh , Haradasht Sadra Amirpour
Published: November 2023

Introduction: The current study is aimed at investigating the epidemiology of zygomatico- maxillary complex fracture in oral and maxillofacial trauma patients in a trauma hospital.
Materials and Methods: This cross-sectional descriptive-analytical study with 187 patients was conducted at Khatam al-Anbia Hospital in Zahedan from April 2018 to December 2021. All the data including etiology, gender, age, ethnicity, year and place of occurrence, and site of fracture were obtained from the medical records of all oral and maxillofacial trauma patients who were subjected to ZMC fracture. Chi-Square and Fisher’s exact tests were used to analyze the data.
Results: Mean age of the patients was 29.53±14.13 years. Out of 187 patients, 87.2% (163 people) were male and 12.8% (24 people) were female. People between 20 and 40 years had more ZMC fractures than other age groups with 104 cases (55.7%). Baluch ethnic group with 111 people (59.3%) experienced more fractures than other ethnic groups. The highest fracture rate occurred in 2021 with 63 cases (33.7%). Street was the most prevalent place of occurrence for fractures with 134 cases (71.6%). Isolated cheek fracture was the most common with 95 cases (51%). The most common cause of fracture was traffic accidents with a prevalence of 71.1%.
Conclusion: The results revealed that traffic accident is the main cause of ZMC fractures in the studied population. Thus, public awareness and strict implementation of traffic policies are needed.
Bicortical stability of implants placed in severely atrophic posterior maxilla: A case report
Authors: Salehi Mojtaba , Hasheminasab Mahboube , Hajiani Narges
Published: November 2023

Maxillary sinus lift is a common procedure to achieve adequate alveolar bone height in patients with sinus hyper-pneumatization. Simultaneous implant placement with sinus floor augmentations is possible when appropriate primary stability could be achieved. In severe atrophic posterior maxillary ridge, vertical bone height is sometimes less than 4mm, which may hinder simultaneous implant placements and necessitate two stage procedure. In current study, a novel technique is described to perform a single stage implant placement with bicortical stability in severe atrophic maxilla that can shorten the treatment time of an edentulous patient. During the procedure, to achieve an adequate access a conventional lateral window osteotomy is performed. After elevating the Schneiderian membrane using conventional instruments, an autologous ramus block is harvested from the mandible and then the block will be fixed in correct location in the sinus using screws with appropriate length to build sufficient stability as superior cortex for simultaneous implant insertion.
Etapas del protocolo de crioconservación y su efecto sobre la viabilidad y regeneración de embriones cigóticos de vid (Vitis vinífera L.)
Authors: Esquivel-Figueroa Deanna , Tiznado-Hernández Martin Ernesto , Islas-Osuna María Auxiliadora , Lazo-Javalera María Fernanda , Rivera-Domínguez Marisela
Published: November 2023

La vid es uno de los principales cultivos del mundo y el estado de Sonora es el mayor productor de México. Este cultivo está en constante peligro por diversos factores bióticos y abióticos, de ahí la importancia de su conservación. La crioconservación es idónea para este cultivo, pero puede provocar alteraciones fisiológicas, moleculares y bioquímicas, afectando la viabilidad y la regeneración. Por lo anterior, en este trabajo se planteó analizar el efecto de las etapas del protocolo de crioconservación sobre la viabilidad y regeneración de embriones cigóticos de vid. La viabilidad del tejido (V) y la regeneración de plántulas (RP), mostraron que la PVS2 ejerce protección a los embriones (V:85%, RP:60%), mientras que la exposición combinada a la solución PVS2 y nitrógeno líquido (NL) ocasionó diminución de la viabilidad y regeneración (V:68%; RP: 2%). Un efecto más drástico se observó cuando el tejido fue expuesto a PVS2+NL y recalentamiento (RC) (V:68%; RP:0%). Sin embargo, la viabilidad y la regeneración se recuperó cuando el tejido se sometió a PVS2+NL+RC y solución de descarga (SD) (V:92%; RP:60%). Se concluye que la utilización de la solución de descarga es fundamental para evitar daños a los tejidos debido a las diferentes etapas de crioconservación.
Revolutionizing Safety and Security in the Chemical and Process Industry: Applying the CHESS concept
Authors: Reniers Genserik , Khakzad Nima
Published: November 2023

This paper argues that a new concept, summarized as ‘CHESS’, should be used in the chemical industry to further substantially advance safety (where we use the term in a broad sense, that is, safety and physical security, amongst others). The different domains that need to be focused upon, and where innovative initiatives should be taken are Cluster-thinking and cooperation, High transparency and efficient inspections, Education and training, Security integration, and Safety innovation. Since society has fundamentally changed over the last two decades, and ever more hazardous materials are used in chemical sites which are ever more closely situated next to highly-populated areas, revolutionizing safety via the CHESS concept is truly needed in the very near future, both from a safety and a security point of view.
Reading comprehension beliefs of Mexican pre-service language teachers: a Likert scale study
Authors: Perales-Escudero Moisés Damián , Garduño Buenfil Mizael , Portillo Campos Vilma Esperanza
Published: November 2023

This paper aims to report the adaptation of a new version of the Scale of Implicit Theories of Reading Comprehension (ETICOLEC as per its Spanish acronym) with a sample of 77 randomly chosen English majors at a peripheral campus of a small university in the Southeast of Mexico. The ETICOLEC Likert scale was originally designed to measure the reading comprehension beliefs of middle school teachers of several subjects. Hence, it was necessary to adapt it to identify the beliefs of pre-service language teachers. A standard procedure recommended by the literature (Prat & Doval, 2005) was used to add new items to the scale and test its psychometric properties using principal component analysis and internal consistency analysis with Cronbach´s alpha. Calculations were performed using the Statistical Package for the Social Sciences (SPSS, v. 26). As with the original ETICOLEC, this adapted version yielded five internally consistent sub-scales, albeit slightly different from the original ones. Each subscale measures an implicit theory or group of beliefs about reading comprehension. As a secondary, exploratory goal, we also describe the participants according to their implicit theories. Most participants held implicit theories that are functional for the kinds of epistemic reading tasks required by their university education. However, a large minority did not appear to hold any firm beliefs about reading, suggesting insufficient exposure to various complex reading tasks and genres. This situation must be addressed to ensure these pre-service teachers become effective reading teachers.
On graphs associated to topological spaces
Authors: Mohammed Salih Haval
Published: November 2023

Let 𝑋 be a set and (𝑋,𝑇) be a topological space. A new type of graph on 𝑃(𝑋), namely the closure graph of 𝑇 is introduced. The closure graph denoted by Γc whose vertex set is 𝑃(𝑋) in which two distinct vertices 𝐴 and 𝐵 are adjacent if A'∩B' ⊆ (A∩B)'. In this paper, the closure graph is shown as a simple, connected graph with diameter at most two. Furthermore, the girth of the closure graph Γcof 𝑇 is three if 𝑋 contains more than one point. Also, several graph properties are studied.
Penggunaan Big Data Dalam Mengungkap Kasus Kejahatan Judi Online di Polrestabes Medan
Authors: Tobing Michael Yusuf , Markus Aruan Miquel Joan , Pakpahan Kartina
Published: November 2023

One of the important benefits of Big Data and Computing Technology in criminal justice is that it is now easier to store and access records. Thanks to things like social media, people save more than usual. It is likely that the physical copies of the old photos are gone or destroyed, but many people have already posted them on Facebook. A criminal may post an incident, photo, or event on social media that can be traced to reveal the crime he committed and to punish or possibly release him. . To tackle gambling on the internet, Law no. 11 of 2008 concerning Electronic Information and Transactions. When dealing with "internet gambling" there are still new problems that arise, especially regarding evidence. The problem is, what are the benefits of using Big Data in disclosing crime cases by Police investigators and how to use big data in uncovering online gambling cases at the Medan Police. This paper uses a doctrinal research approach. Research results: The use of Big Data to disclose criminal acts should not neglect the protection of the owner of personal data. Subnit VC Sat.Reskrim Polrestabes Medan does not understand technological developments, so it is difficult to use Big Data in uncovering cases of online gambling. It is recommended that Medan Police Investigators attend information technology training and guidance.
Hybrid and chimeric nitrogen heterocycles with biological activity
Authors: Mangalagiu Violeta , Diaconu Dumitrela , Moldoveanu Costel , Zbancioc Gheorghita , Danac Ramona , Amariucai-Mantu Dorina , Antoci Vasilichia , Mangalagiu Ionel
Published: November 2023

Nitrogen heterocycles, especially azine and azole derivatives, are highly valuable scaffolds in medicinal chemistry, being the core components of a large variety of drugs with variously biological activity such as antiplasmodial and antimalarial, antitubercular, antibacterial, antifungal, anticancer, analgesic, antidepressant, anxiolytics, antihypertensive, anticoagulants, diuretics, etc. As a result, obtaining of such entities continues to arouse a strong interest from academia and industry. As part of our ongoing research in the area of nitrogen heterocyclic derivatives, we present herein some representative results obtained by our group in the field of hybrid and chimeric azahetrocycles compounds with antimicrobial and anticancer activity. Chemistry, anticancer, antibacterial, antifungal and antituberculosis activity of compounds is presented. Some of the hybrid and chimeric structures possess a good anticancer and/or antimicrobial activity.
Photochemical transformation of some (+)-Larixol derivatives
Authors: Ciocarlan Alexandru , Lungu Lidia , Blaja Svetlana , Kuchkova Kaleria , Aricu Aculina
Published: November 2023

n terms of synthetic potential, (+)-larixol 1 outperform other labdanic diterpenoids due to the hydroxyl group at the C6 position. Over the years, various chemical transformations have been performed on the basis of this compound, selectively or on both hydroxyl groups, or by modifying of the side chain [1-4]. Unlike the syntheses mentioned above, only a few are known with the preservation of the side chain or its rearrangement and functionalization in cycle B [5,6]. Herein, the syntheses of (+)-larixol 1 derivatives with an advanced degree of functionalization of the B cycle and preservation of the side chain will be described, by combining classical and nonconventional methods, such as sensitized photooxidation. Starting from (+)-larixol 1, in three steps the intermediate ketoacetate 2 was obtained in 86% overall yield. Next, compound 2 was subjected to the enolacetylation reaction, which led to undescribed before enolacetates 3 and 4 in depicted yields (see Scheme). Compounds 3 and 4, due to their conjugated diene systems, were subjected to photochemical transformations.
Synthesis of 1,3-Phenyl(Pyridyl)propenones with thiosemicarbazidic groups
Authors: Popusoi Ana , Barba Nicanor , Gulea Aurelian
Published: November 2023

The bibliographic study of chalcones of the type 1,3-aryl(heteryl)propen-2-one with thiosemicarbazidic 4- and 1,4-disubstituted and thisemicarbazonic groups respectively gives us the information that they have a wide spectrum of biological activity, but methods of their synthesis are less described in the literature, and they became our object of study. 4,5-Dihydro-1-H-(pyrazol-3-yl)phenylhydrazinecarbothioamides 3a and 3b were obtained according to the following scheme:Reagents and reaction conditions: i, ii) 2-Py, 25oC – 24h, 90-95oC – 3h, 77-82%; iii) DMF, CH3COOH, 70-80oC, 2-3h, 60-63%. Figure 1. Synthesis of chalcone derivatives 3a, 3b, 4a and 4b.Initially N,N-dimethylthioureas 1a and 1b with hydrazine hydrate from hydrazones in pyridine at room temperature, which without being isolated upon heating cyclize to pyrazole derivatives (Fig. 1.) as described in the literature, and in parallel, dimethylamine is substituted by the hydrazine group [1] with the formation of compounds 3a and 3b, with a yield of 77%. Compound 3a was also obtained by an alternative route from isothiocyanatophenylpropen-2one 2a and hydrazine hydrate at room temperature, then on heating in pyridine (Fig. 1.). It is possible to from the same intermediates, which turn in to the finished product 3a, the yield is 82%. Compounds 4a and 4b were obtained from products 3a and 3b by boiling in ethanol with 2-pyridinecarboxyaldehyde. The antiproliferative activity of N-(4-(5-(pyridine-2-yl)-4,5dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridine-2-ylmethylene)hydrazinecarbotioamide towards HL-60 leukemia cells were patented [2].
Phenolic compounds in Agrimonia eupatoria l. Ethanolic extract evaluated by HPLC
Authors: Cojocaru-Toma Maria , Valica Vladimir , Gandacov Vladilena , Mazur Ecaterina , Uncu Livia
Published: November 2023

Agrimonia eupatoria L. (Rosaceae fam.) is widespread in temperate regions. In folk medicine, this species has been used for its astringent, analgesic and anti-inflammatory, as well as in gastrointestinal disorders. As these biological properties have been linked to its phenolic composition, this plant species could be an interesting source of bioactive compounds with therapeutic potential [1]. For the evaluation of chemical compounds in A. eupatoria extract, the aerial parts were harvested in the flowering period from the collection of the Scientific Practical Centre in the Field of Medicinal Plants of “Nicolae Testemițanu” State University of Medicine and Pharmacy. The dry extracts were concentrated using a rotary evaporator-Laborota 4011. The analysis was performed on Shimadzu LC-20AD chromatograph with SPD-20A UV detector [2], under the following conditions: stationary phase - Zorbax Exlipse Plus C18 (4.6x250 mm, 5 microns); 2 mobile phases: solvent mixture: methanol: water (40:60) with gradient elution and orthophosphoric acid 0.5%: acetonitrile (80:20) with isocratic elution mode; detection at wavelengths of 280, 325 and 360 nm. The solvent system that achieved optimal separation of the phenolic compounds was the mixture of 0.5% orthophosphoric acid:acetonitrile (80:20) at a wavelength of 325 nm. The extract of A. eupatoria was found to be richer in tannins (catechin-3.68%, epicatechin-2.59%); in flavonoids (rutin-1.71%, quercetin-0.199%, luteolin-0.184%, kaempferol-0.162%, apigenin-0.078%, with a lower content of hydroxycinnamic acids (chlorogenic, caffeic, cycoric and ellagic). The HPLC method with UV-VIS detection can be successfully used in the identification and quantitative determination of chemical compounds in Agrimonia eupatoria extracts for the development and standardization of new pharmaceutical forms.
Nucleophilic addition of pyridine amines to the double bond of in situ generated morita-baylis-hillman adducts from indole-2,3-dione
Authors: Sucman Natalia
Published: November 2023

This report will present the results of addition reactions of indole-2,3-dione to methyl or nitryl acrylate and amino-methyl-pyridine. The addition of an activated alkene like methyl acrylate and nitryl acrylate to a carbon electrophile in the presence of a nucleophilic catalyst is named Morita-Bailys Hillman (MBH) addition. Such adducts are very popular in organic chemistry [1-3]. As a result of screening various substances in search of new catalysts in MBH reactions, substances were discovered that not only catalyzed the addition of olefin to a carbonyl compound but also acted as a reagent themselves, leading to the formation of fundamentally new substances (Figure 1). After analyzing NMR spectra, conclusions were drawn about the structure of the substance, which was subsequently confirmed by X-ray structural analysis. Figure 1. General scheme of nucleophilic addition of pyridine amines to the double bond of in situ generated Morita-Baylis-Hillman adducts It should be noted that methyl acrylate reacts better under these conditions, and the reaction proceeds faster than acrylonitrile. In all cases, the yield was around 70%, and the reaction proceeded regioselectively, forming only one diastereomeric pair of enantiomers. It is also worth noting that the complex ether product hydrolyzes during the reaction, forming the corresponding acid. Even when the reaction is carried out under practically absolute conditions, up to 30% of the final product yield is attributed to the acid.
Total content of flavonoids in species of the genus heichrysum
Authors: Nartea Mihaela , Cojocaru-Toma Maria , Ciobanu Cristina , Benea Anna , Cristeva Maria
Published: November 2023

The genus Helichrysum (Asteraceae) comprises about 600 species of perennial or annual plants distributed in Europe, Asia, and Africa, which are an abundant source of secondary metabolites, such as flavonoids, chalcones, phenolic acids, coumarins, pyrones, and terpenes [1]. In the Republic of Moldova only one species H. arenarium (L.) Moench-(popularly known as everlasting), occurs sporadically on the cliffs of the right bank of the Nistru River, in the landscape reserve "Climăuții de jos", in the Steppe Hills steppes, on the limestones of Naslavcea, with a declining population [2]. Another species H. italicum L. is recently introduced (2021) in the collection of the Scientific Practical Centre in the Field of Medicinal Plants of “Nicolae Testemițanu” State University of Medicine and Pharmacy. We proposed identification and assay of flavonoids from species of the genus Heichrysum (H. arenarium and H. italicum). Aerial parts and flowers of H. arenarium were collected from wild flora, and for H. italicum - from the collection. Flavonoids were identified by specific reactions as well as by thin layer chromatography. Determination of flavonoids was performed with aluminium chloride using a Metertech UV/VIS SP 8001 spectrophotometer. By colour reactions and CSS in the aerial parts and flowers of H. arenarium were identified: apigenin, luteolin, rutozide, quercetin, quercitrin, while in H. italicum: apigenin, rutozide, luteolin. The flavonoid concentration (mg/ml), expressed as rutin (λ=430nm) shows a higher content in the H. arenarii flores (1.46), followed by the H. italici flores (1.31), while the flavonoid content in the aerial parts is lower and varies from 0.80 for H. italicum to 0.89 for H. arenarium. Where the total flavonoid content (mg/ml), expressed as quercetin (λ=425nm) is higher and shows 10,69 in H. arenarii flores; 9,87 in H. italici flores, followed by aerial parts (2,76 for H. italicum to 3,62 for H. arenarium) with a maximum extraction in ethanol of 50% for all products.
The importance of adaptive sports for the social adaptation of persons with disabilities
Authors: Begidov Mikhail V. , Begidova Tamara P. , Bespalova Vlada V.
Published: November 2023

Importance. According to many scientists, adaptive sports have the most productive effect on the social adaptation of persons with disabilities. There are a number of difficulties that people in this category face. The importance of adaptive sports was analyzed, a number of its problems were identified. The purpose of the study: scientific substantiation of the role of adaptive sports in the socialization of people with disabilities.
Materials and Methods. The study was conducted during 2021–2023. Interviews and questioning of athletes of the Paralympics movement of the Russian Federation were aimed at identifying the prospects for the development of adaptive sports and its impact on social adaptation. As respondents, 12 athletes with a violation of the musculoskeletal system or vision in the most massive sports disciplines – swimming and athletics, aged 22 to 48 years old were selected: 2 Honored Masters of Sports of the Russian Federation, 5 Masters of Sports of the Russian Federation of international class and 5 Masters of Sports of the Russian Federation. The object of the study is the process of practicing adaptive sports for people with disabilities. The subject of the study is the socialization of persons with disabilities in the process of practicing adaptive sports.
Results and Discussion. The data obtained on the effectiveness of the impact of adaptive sports on the social adaptation of persons with disabilities were analyzed.
Conclusion. The data obtained confirm the effectiveness of adaptive sports in the socialization of persons with disabilities, which will improve the organization and development of adaptive sports in Russia, leading to an increase in the number of people involved and their effective socialization.
RELATIONSHIP BETWEEN PERSONAL HYGIENE AND ECHERICHIA COLI BACTERIA ON THE PALM OF CHILDREN’S SDN X IN KEDIRI CITY
Authors: Muarofah Binti , Merlinda Puput Dinda
Published: November 2023

IntroductionMethod: The design used was cross sectional study. The population was 56. Sampling used Quota Sampling, namely 30 palm swabs from Children at SDN X In Kediri City. In giving scores for Personal Hygiene, a Likert scale was used. Materials used for research were EMB, TSIA, UREA and IMVC media, tools used were coot swabs , incubator, oven and autoclav, personal hygiene variables and Echerichia coli bacteria, research carried out from April to May 2023 Chi-square test analysis using SPSS (Statistical Program For Social Science). The results: 29 samples identified the presence of bacteria and 1 sterile sample, identified bacteria including Salmonella sp (30%) also found Klebsiella sp (20%) and Echerichia coli (47%) bacteria. The personal hygiene of the chindren showed 50% has bad personal hygiene, 43% has good personal hygiene and 7% has very good personal hygiene. As well as showing the presence of Echerichia coli bacteria on the palms of elementary school children. Conclusion A significant relationship was found in the statistical test because the results showed an Asymp.Sig value of 0.000 where the value <0.05 where Ha was accepted and H0 was rejected.
FABRICATION OF MAYNE’S SPACE MAINTAINER FOR PREMATURE LOSS OF DECIDUOUS TEETH
Authors: Goenharto Sianiwati , Haula Robbi M. Kautsar , Inayati Eny , Setyowati Okti , Kusdarjanti Endang , Laksmi Lita Rosa Mia , Sujati  , Wahjuni Sri , Redjeki Sri , Nur Halimah Anisa
Published: November 2023

Background: Premature loss for deciduous teeth is defined as the teeth that fall out before approaching the time of eruption of their replacement permanent teeth regardless of the reason for the loss of the teeth. The premature loss of deciduous teeth can cause the teeth next to the edentulous area to shift and lose arch space causing permanent teeth to grow abnormally. Prevention can be done by using Mayne's space maintainer so that the negative impact of premature loss does not occur. Purpose: Report the fabrication of Mayne's space maintainer in premature loss case. Case analysis: The laboratory accepted a working model with a case of premature loss in tooth 74 and was asked to make the Mayne's space maintainer. Result: This appliance consists of a molar band attached to tooth 75 with a 0.9 mm loop that is soldered on the buccal of the molar band. Conclusion: It is concluded that fabrication of Mayne's space maintainer in the case of premature loss of tooth 74 includes the preparation of a working model, adjustment of the molar band on tooth 75, making the loop, followed by soldering the loop to the molar band, finally the finishing and polishing.
Euclides de Aquino Fonseca e a sua produção para o palco: breve histórico e as questões orquestrais da ação lendária Leonor (1883) e do drama bíblico Il Maledetto (1902)
Authors: Dias Sérgio
Published: November 2023

A produção musical destinada à cena pelo compositor pernambucano Euclides de Aquino Fonseca (1854-1929) ocupa um papel de destaque em seu precioso catálogo de obras hoje disponíveis. No entanto, quatro de seus títulos sobreviventes – dos quais se nos apresentam duas tragédias e duas comédias – emanam muitos problemas relacionados, sobretudo, aos universos da poética, da instrumentação e da orquestração. Deixando de lado a problemática relacionada aos libretos, neste pequeno trabalho, e a partir de uma criteriosa análise das fontes originais, secundárias e correlatas, tentamos abordar os principais tirocínios instrumentais do mestre naquele âmbito teatral, sugerindo achegas que possam contribuir, em futuro próximo, para os esforços de reconstrução de tal conjunto de obras.