bluuebunny/crossref_metadata_2025 huggingface dataset:
Translation of Nutritional Genomics into Nutrition Practice: The Next Step
Authors: Murgia Chiara , Adamski Melissa M.
Published: April 2017

Genetics is an important piece of every individual health puzzle. The completion of the Human Genome Project sequence has deeply changed the research of life sciences including nutrition. The analysis of the genome is already part of clinical care in oncology, pharmacology, infectious disease and, rare and undiagnosed diseases. The implications of genetic variations in shaping individual nutritional requirements have been recognised and conclusively proven, yet routine use of genetic information in nutrition and dietetics practice is still far from being implemented. This article sets out the path that needs to be taken to build a framework to translate gene–nutrient interaction studies into best-practice guidelines, providing tools that health professionals can use to understand whether genetic variation affects nutritional requirements in their daily clinical practice.
Introduction to This Issue
Authors: Himes Kenneth , Ward Kate
Published: April 2017

Only a few decades ago, the neoconservative writer Irving Kristol could dismiss economic inequality as a social problem (Kristol 1980).[...]
Accurate Simulation of Parametrically Excited Micromirrors via Direct Computation of the Electrostatic Stiffness
Authors: Frangi Attilio , Guerrieri Andrea , Boni Nicoló
Published: April 2017

Electrostatically actuated torsional micromirrors are key elements in Micro-Opto-Electro- Mechanical-Systems. When forced by means of in-plane comb-fingers, the dynamics of the main torsional response is known to be strongly non-linear and governed by parametric resonance. Here, in order to also trace unstable branches of the mirror response, we implement a simplified continuation method with arc-length control and propose an innovative technique based on Finite Elements and the concepts of material derivative in order to compute the electrostatic stiffness; i.e., the derivative of the torque with respect to the torsional angle, as required by the continuation approach.
The Physical Layer Security Experiments of Cooperative Communication System with Different Relay Behaviors
Authors: Su Yishan , Han Guangyao , Fu Xiaomei , Xu Naishen , Jin Zhigang
Published: April 2017

Physical layer security is an attractive security mechanism, which exploits the randomness characteristics of wireless transmission channel to achieve security. However, it is hampered by the limitation of the channel condition that the main channel must be better than the eavesdropper channel. To alleviate the limitation, cooperative communication is introduced. Few studies have investigated the physical layer security of the relay transmission model. In this paper, we performed some experiments to evaluate the physical layer security of a cooperative communication system, with a relay operating in decode-and-forward (DF) cooperative mode, selfish and malicious behavior in real non-ideal transmission environment. Security performance is evaluated in terms of the probability of non-zero secrecy capacity. Experiments showed some different results compared to theoretical simulation: (1) to achieve the maximum secrecy capacity, the optimal relay power according to the experiments result is larger than that of ideal theoretical results under both cooperative and selfish behavior relay; (2) the relay in malicious behavior who forwards noise to deteriorate the main channel may deteriorate the eavesdropper channel more seriously than the main channel; (3) the optimal relay positions under cooperative and selfish behavior relay cases are both located near the destination because of non-ideal transmission.
Mover Position Detection for PMTLM Based on Linear Hall Sensors through EKF Processing
Authors: Yan Leyang , Zhang Hui , Ye Peiqing
Published: April 2017

Accurate mover position is vital for a permanent magnet tubular linear motor (PMTLM) control system. In this paper, two linear Hall sensors are utilized to detect the mover position. However, Hall sensor signals contain third-order harmonics, creating errors in mover position detection. To filter out the third-order harmonics, a signal processing method based on the extended Kalman filter (EKF) is presented. The limitation of conventional processing method is first analyzed, and then EKF is adopted to detect the mover position. In the EKF model, the amplitude of the fundamental component and the percentage of the harmonic component are taken as state variables, and they can be estimated based solely on the measured sensor signals. Then, the harmonic component can be calculated and eliminated. The proposed method has the advantages of faster convergence, better stability and higher accuracy. Finally, experimental results validate the effectiveness and superiority of the proposed method.
Sensor Fusion of a Mobile Device to Control and Acquire Videos or Images of Coffee Branches and for Georeferencing Trees
Authors: Giraldo Paula , Aguirre Álvaro , Muñoz Carlos , Prieto Flavio , Oliveros Carlos
Published: April 2017

Smartphones show potential for controlling and monitoring variables in agriculture. Their processing capacity, instrumentation, connectivity, low cost, and accessibility allow farmers (among other users in rural areas) to operate them easily with applications adjusted to their specific needs. In this investigation, the integration of inertial sensors, a GPS, and a camera are presented for the monitoring of a coffee crop. An Android-based application was developed with two operating modes: (i) Navigation: for georeferencing trees, which can be as close as 0.5 m from each other; and (ii) Acquisition: control of video acquisition, based on the movement of the mobile device over a branch, and measurement of image quality, using clarity indexes to select the most appropriate frames for application in future processes. The integration of inertial sensors in navigation mode, shows a mean relative error of ±0.15 m, and total error ±5.15 m. In acquisition mode, the system correctly identifies the beginning and end of mobile phone movement in 99% of cases, and image quality is determined by means of a sharpness factor which measures blurriness. With the developed system, it will be possible to obtain georeferenced information about coffee trees, such as their production, nutritional state, and presence of plagues or diseases.
Measuring Complexity and Predictability of Time Series with Flexible Multiscale Entropy for Sensor Networks
Authors: Zhou Renjie , Yang Chen , Wan Jian , Zhang Wei , Guan Bo , Xiong Naixue
Published: April 2017

Measurement of time series complexity and predictability is sometimes the cornerstone for proposing solutions to topology and congestion control problems in sensor networks. As a method of measuring time series complexity and predictability, multiscale entropy (MSE) has been widely applied in many fields. However, sample entropy, which is the fundamental component of MSE, measures the similarity of two subsequences of a time series with either zero or one, but without in-between values, which causes sudden changes of entropy values even if the time series embraces small changes. This problem becomes especially severe when the length of time series is getting short. For solving such the problem, we propose flexible multiscale entropy (FMSE), which introduces a novel similarity function measuring the similarity of two subsequences with full-range values from zero to one, and thus increases the reliability and stability of measuring time series complexity. The proposed method is evaluated on both synthetic and real time series, including white noise, 1/f noise and real vibration signals. The evaluation results demonstrate that FMSE has a significant improvement in reliability and stability of measuring complexity of time series, especially when the length of time series is short, compared to MSE and composite multiscale entropy (CMSE). The proposed method FMSE is capable of improving the performance of time series analysis based topology and traffic congestion control techniques.
Lack of Reality: Positive Self-Perceptions of Health in the Presence of Disease
Authors: Dalbo Vincent , Teramoto Masaru , Roberts Michael , Scanlan Aaron
Published: April 2017

The aim of this study was to determine if adults in Central Queensland have accurate self-perceptions of health. Data were collected as part of the 2010 Central Queensland Social Survey (N = 1289). Overweight/obesity is considered a health disorder and was determined using body mass index. Disease states were determined by asking respondents if they have: heart disease, high/low blood pressure, high cholesterol, high triglycerides, thyroid disorder, diabetes, and osteopenia/osteoporosis. Self-perceptions of health were assessed by asking, “Would you say that in general your health is” poor, fair, good, very good, excellent, don’t know, and no response. An accurate health perception occurred if: (1) A respondent with a disease/health disorder reported that their health was poor/fair or (2) A respondent without a disease/health disorder reported that their health was good/very good/excellent. The proportions of people with an accurate health perception by disease/health disorder were compared using a χ2 test. A proportion ratio (PR) with a 95% confidence interval (CI) was calculated for each disease/health disorder. A logistic regression analysis was performed to examine the association between each disease/health disorder and health perception using gender, age, education, physical activity level, and smoking status as covariates. More than 50% of residents with each disease/health disorder reported their health to be good/very good/excellent. Residents with each disease/health disorder were less likely to have an accurate health perception than those without the corresponding disease/health disorder prior to (p < 0.001) and following adjustment of the covariates (p < 0.001). Our results suggest that overweight/obesity and prevalence of disease are not being recognized as unhealthy, which contradicts established definitions of health.
Explore the Buffering Effects of Perceived Hidden Inflation on Survival of Mobile Phone Service Providers in Taiwan
Authors: Liu Sheng-Wen , Yang Ying-Chieh , Norcio Ralph
Published: April 2017

The purpose of this study is to examine the moderating role of perceived hidden inflation on the relationships between service quality, brand trust and brand loyalty. All data collected from the target population are analyzed through two-step structural equation modeling (SEM) and moderated multiple regression (MMR) to examine the hypotheses. 1,050 questionnaires are randomly distributed at 21 telecommunication service stores in Taiwan. Findings indicated that service quality has no direct impact on behavioral loyalty but it has a significant indirect impact on behavioral loyalty through brand trust or attitudinal loyalty. Moreover, findings identify perceived hidden inflation as the moderating role in the service quality–brand trust–brand loyalty chain. Besides the need for empirical confirmation of the hypotheses given, finally, there are several practical implications for service marketers and future research directions for scholars.
A Study on Applying Biomass Fraction for Greenhouse Gases Emission Estimation of a Sewage Sludge Incinerator in Korea: A Case Study
Authors: Kang Seongmin , Kim Seungjin , Lee Jeongwoo , Jeon Youngjae , Kim Ki-Hyun , Jeon Eui-chan
Published: April 2017

According to the IPCC (Intergovernmental Panel on Climate Change) guidelines, when calculating CO2 emissions, CO2 emissions from biomass should be excluded from the total amount of CO2 emissions and should be separately reported due to their “carbon neutrality”. Sewage sludge is one of the representative biomass fuels. It is mixed with fossil fuels to achieve greenhouse gas reduction or is used by itself as a fuel to replace fossil fuels. According to the results of this study, biomass fractions of both the sewage sludge and the sewage sludge incineration exhaust gases did not amount to 100%. At present, in many countries (South Korea, Japan, and Germany), when calculating greenhouse gas emissions from sewage sludge incinerators, all CO2 emissions from sewage sludge are judged to be biomass and only the greenhouse gas emissions that correspond to non-CO2 gases are calculated as greenhouse gas emissions. However, since, according our results, the content of sewage sludge is not 100% biomass, if CO2 emissions are excluded according to the existing greenhouse gas emission calculation method, the amount of emissions may be underestimated. Therefore, to accurately calculate greenhouse gas emissions from a sewage sludge incinerator, CO2 emissions should be calculated in consideration of the fossil carbon fractions of sewage sludge.
Description de deux nouvelles Salticidae (Araneae) de Mayotte (Comores)
Authors: Dierkens Michaël
Published: April 2017

Deux nouvelles Salticidae, Asemonea bimaculata et Padilla rhizophorae, sont décrites de Mayotte.
Contribution à l'étude des Araneidae de Guyane française. V - Les genres Alpaida et Ocrepeira
Authors: Dierkens Michaël
Published: April 2017

Contribution to the study of Araneidae from French Guiana. V-The genera Alpaida and Ocrepeira. - This paper deals with the species of the genera Alpaida and Ocrepeira (Araneidae) in French Guiana. Alpaida monzon audiberti, Alpaida ovapockensis and Ocrepeira maroni are described. Nine other species are recorded for the first time from this department.
Une étude locale de la biodiversité : inventaire des coléoptères du domaine de la Fondation Pierre Vérots à Saint-Jean-de-Thurigneux (Ain, France). 1. Les carabiques et cicindèles
Authors: Prudhomme Jean-Claude
Published: April 2017

Une liste de 124 carabiques et cicindèles rencontrés lors de l'inventaire des coléoptères du domaine de la Fondation Pierre Vérots à Saint-Jean-de-Thurigneux (Ain) est établie, commentée et comparée aux données anciennes et récentes disponibles pour la même région.
Extraction of 223Radium by haemodialysis after treatment of metastatic castration-resistant prostate cancer
Authors: Wissel Heiko , Wallbaum Thekla , Genseke Philipp , Kupitz Dennis , Ricke Jens , Ruf Juri , Amthauer Holger , Großer Oliver Stephan
Published: April 2017

Aim:
223Radium-dichloride (223Ra) administration is an upcoming therapeutic option in patients with castration-resistant metastatic prostate cancer (mCRPC), whose renal and faecal excretion of 223Ra has been primarily estimated from data of a phase-I clinical trial in patients with normal renal function. In the rare case of concomitant renal insufficiency requiring haemodialysis (HD), an estimation of the contamination of dialysate would be beneficial. Methods: The excretion of 223Ra and its concentration in the dialysate in a patient with mCRPC and end-stage renal disease was examined for six consecutive treatment cycles. Dialysate samples were measured using a commercial system with NaI-scintillation detector. Results: HD showed a residual activity level in the remaining dialysate. The excreted activity was a median of 46.1 kBq (range = 42.0 83.4 kBq) and 11.2 kBq (range = 8.419.9 kBq) for the first (24 h post injection p.i.) and second HD (96 h p.i.), respectively. The activity concentration decreased significantly from a median of 4.18 kBq/l (range = 2.98-5.14 kBq/l) to 0.85 kBq/l (range=0.69-1.31 kBq/l, p < 0.0001). For all consecutive time points, the activity concentration further decreased significantly (p < 0.0001). The activity concentration of dialysate from HD performed 125.4 h p.i. [95 % confidence interval = 120.5-130.4 h p.i.] reached the threshold for unrestricted waste disposal. Conclusion: The observed extraction of 223Ra by HD exceeded the data determined from the phase-I study. The activity concentration in the dialysate observed for the first HD’s p.i. was above the threshold for unrestricted disposal of radioactive waste in Germany. Therefore, the specific requirement for waste handling has to be followed to fulfil the radiation protection regulations.
Connecting Clump Sizes in Turbulent Disk Galaxies to Instability Theory
Authors: Fisher David B. , Glazebrook Karl , Abraham Roberto G. , Damjanov Ivana , A. White Heidi , Obreschkow Danail , Basset Robert , Bekiaris Georgios , Wisnioski Emily , Green Andy , Bolatto Alberto D.
Published: April 2017

In this letter we study the mean sizes of Hα clumps in turbulent disk galaxies relative to kinematics, gas fractions, and Toomre Q. We use ∼100 pc resolution HST images, IFU kinematics, and gas fractions of a sample of rare, nearby turbulent disks with properties closely matched to

main-sequence galaxies (the DYNAMO sample). We find linear correlations of normalized mean clump sizes with both the gas fraction and the velocity dispersion-to-rotation velocity ratio of the host galaxy. We show that these correlations are consistent with predictions derived from a model of instabilities in a self-gravitating disk (the so-called “violent disk instability model”). We also observe, using a two-fluid model for Q, a correlation between the size of clumps and self-gravity-driven unstable regions. These results are most consistent with the hypothesis that massive star-forming clumps in turbulent disks are the result of instabilities in self-gravitating gas-rich disks, and therefore provide a direct connection between resolved clump sizes and this in situ mechanism.
A Framework to Combine Low- and High-resolution Spectroscopy for the Atmospheres of Transiting Exoplanets
Authors: Brogi M. , Line M. , Bean J. , Désert J.-M. , Schwarz H.
Published: April 2017

Current observations of the atmospheres of close-in exoplanets are predominantly obtained with two techniques: low-resolution spectroscopy with space telescopes and high-resolution spectroscopy from the ground. Although the observables delivered by the two methods are in principle highly complementary, no attempt has ever been made to combine them, perhaps due to the different modeling approaches that are typically used in their interpretation. Here, we present the first combined analysis of previously published dayside spectra of the exoplanet HD 209458 b obtained at low resolution with HST/Wide Field Camera 3 (WFC3) and Spitzer/IRAC and at high resolution with VLT/CRIRES. By utilizing a novel retrieval algorithm capable of computing the joint probability distribution of low- and high-resolution spectra, we obtain tight constraints on the chemical composition of the planet’s atmosphere. In contrast to the WFC3 data, we do not confidently detect H2O at high spectral resolution. The retrieved water abundance from the combined analysis deviates by 1.9σ from the expectations for a solar-composition atmosphere in chemical equilibrium. Measured relative molecular abundances of CO and H2O strongly favor an oxygen-rich atmosphere (C/O < 1 at

) for the planet when compared to equilibrium calculations including O rainout. From the abundances of the seven molecular species included in this study we constrain the planet metallicity to 0.1–1.0× the stellar value (1σ). This study opens the way to coordinated exoplanet surveys between the flagship ground- and space-based facilities, which ultimately will be crucial for characterizing potentially habitable planets.
Réflexion à partir d’une psychothérapie en milieu carcéral : dépendance addictive, contenance, subjectivation et transfert
Authors: Pelladeau Élise , Marchand Jean-Baptiste , Pommier François
Published: April 2017

Cet article traite de la prise en charge psychothérapeutique d’une patiente incarcérée pour des délits répétés. Il illustre les difficultés de traitement de cette patiente qui présentait une vulnérabilité addictive massive en lien avec d’importantes fragilités narcissiques, nous amenant à questionner ces dimensions au regard du transfert dans un lieu clos, comme en miroir des difficultés psychopathologiques des patients. Dans un premier temps nous évoquons le contexte de la rencontre thérapeutique. Puis, nous nous intéressons au retentissement de l’addiction dans le transfert ainsi qu’aux liens de cette problématique avec différents événements traumatiques convoqués au temps des entretiens. Enfin, nous nous attardons, à la lumière de ce cas, sur les particularités du cadre carcéral dans la prise en charge de patients limites.
Israël : colonisation, brutalisation, radicalisation
Authors: Vidal Dominique
Published: April 2017

Relisons les commentaires suscités, voici vingt-cinq ans, par les accords d’Oslo : la paix était à portée de main. Illusion. Après l’assassinat d’Itzhak Rabin, les gouvernements israéliens successifs ont transformé le processus de paix en processus de colonisation. Parallèlement, ils ont fait de leur pays le meilleur élève de la classe néo-libérale, accroissant considérablement les inégalités et contribuant ainsi à la radicalisation à droite d’Israël.
Les Balkans ne sont pas guéris
Authors: Chiclet Christophe
Published: April 2017

En 1991, les Balkans ont commencé à connaître un nouveau séisme comme ils en ont connu d’autres avant. Les premières élections libres dans l’espace yougoslave ont conduit progressivement à la guerre civile. Depuis la fin de la guerre en 1995 qui sera suivie par un nouvel épisode tragique au Kosovo en 1989-1999, rien n’a vraiment été solutionné, sinon le retour à une très fragile stabilité. Les économies et les institutions demeurent souvent livrées aux prédateurs. Qui plus est le repli communautaire est marqué. Le risque de nouvelle explosion est loin d’être écarté.
L’Iran depuis la fin de la Guerre froide : l’impossible quête d’une « démocratie islamique »
Authors: Therme Clément
Published: April 2017

Après la fin de la Guerre froide (1991), on assiste à un premier aggiornamento des révolutionnaires iraniens islamistes sur la question de l’identité de leur Révolution. Plusieurs raisons expliquent ce questionnement : d’abord, la fin de la Guerre froide pose la problématique de la légitimité populaire de la théocratie islamiste dans une ère où la démocratisation apparaît comme l’horizon indépassable des systèmes politiques ; ensuite, avec la fin de la Première Guerre du Golfe (1980-1988), l’indispensable reconstruction économique du pays requiert une large participation de la population ; enfin, la réussite des réformes nécessite une détente dans les relations internationales du pays : ce sera donc la promotion du dialogue des civilisations à partir de 1997. Finalement, le fonctionnement autoritaire va perdurer ensuite. Cet article vise à clarifier les caractéristiques du paradoxe iranien : échec de la démocratisation du système politique théocratique et persistance d’un libéralisme persan.
Projet euro-méditerranén, une nécessaire reconstruction
Authors: Coustillière Jean-François
Published: April 2017

Vingt ans après le lancement du processus de Barcelone, la Méditerranée souffre d’une situation qui s’est régulièrement dégradée pour connaître aujourd’hui conflits armés, déroutes économiques et régimes enkystés. Seule au Sud la Tunisie, peut-être, poursuit son rêve démocratique. Le projet d’un partenariat global aux ambitions partagées de paix et de prospérité n’est plus de mise. Confrontée à de multiples ingérences de puissances étrangères à son espace, la Méditerranée est-elle en mesure d’imaginer de nouvelles voies de coopération et de progrès vers une croissance inclusive et sereine ?
D’un battement d’oreille
Authors: Clavurier Vincent
Published: April 2017

On lit parfois que la coupure de la séance n’est pas adaptée à la cure d’un sujet psychotique. Revenir à la controverse de la scansion permet de rappeler comment la pratique du psychanalyste relève du champ général de la ponctuation. Celle-ci n’est pas totalement réductible à un enjeu sémantique. Elle concerne aussi la pulsion. Un détour par l’examen des ressorts du montage cinématographique permet de soutenir que la cure révèle et installe un montage de la pulsion invocante dans lequel certaines interventions de l’analyste – dont la levée de séance – fonctionnent à la manière d’un battement d’oreille. L’obstacle à l’efficacité d’une telle ponctuation de la parole tient davantage à la méconnaissance, comme refus de s’entendre dire, position subjective de folie sourde, qu’à une structure psychopathologique spécifique (psychose).
À propos des Lettres entre Freud et Bleuler
Authors: Lepoutre Thomas
Published: April 2017

Le présent article prend occasion de la récente publication des Lettres entre Freud et Bleuler pour réinterroger le mode de réception de la psychanalyse par la psychiatrie, en son équivocité foncière. Cette lecture nous invite en effet à méditer ce fait que la réception de la psychanalyse est toujours inséparable d’une résistance à la psychanalyse. Cette ambivalence structurelle s’y signifie exemplairement « en-deux-temps », dans cette sorte de « réaction épistémique négative » que contracte Bleuler à la fréquentation du discours freudien. Un premier temps de fascination initiale due à ce que la psychanalyse rend compréhensible dans la schizophrénie, que Bleuler concevra comme un véritable « panégyrique » des idées freudiennes (1904-1911), précède ainsi une distanciation toujours plus critique, par laquelle il semble que Bleuler revienne sur ce geste qui coûte, de suivre Freud (1911-1914).
L’écoute de la langue du transfert
Authors: Oury Nicole
Published: April 2017

Résumé Freud écoute Hans par la lorgnette paternelle et à partir du matériel clinique rapporté il entend ce qui trouble ce père : ce qu’il peut exprimer ou méconnaît de ce que son fils éveille ou réveille en lui et l’enfant, lui, gagne en liberté de penser. Le processus d’écoute à l’œuvre chez Winnicott permet au patient d’affronter au plus près sa souffrance psychique et de pouvoir se penser en tant que sujet. Un nécessaire refusement est propice à l’installation du cadre analytique et à l’utilisation de sa méthode dans la visée de permettre à la langue du transfert d’advenir. Deux positions se recouvrent chez tout analyste : l’écoute du transfert le contraint à revisiter « ses théories » et dans le même temps à porter attention à l’inattendu, en se saisissant, du travail des mots comme inscription et représentation sensible des affects. L’écoute précède le temps de l’interprétation, créatrice de sens et du plaisir de penser chez les deux protagonistes.
Troubles dans les rapports sociaux : le cas de l’anorexie et de la boulimie
Authors: Scodellaro Claire , Pan Ké Shon Jean-Louis , Legleye Stéphane
Published: April 2017

Les troubles de santé mentale questionnent implicitement et de façon singulière les tensions du monde social. L’anorexie mentale et la boulimie, deux troubles du comportement alimentaire, sont appréhendées ici comme des révélateurs de tensions sociales touchant particulièrement des jeunes filles, et plus souvent issues de classes moyennes ou aisées. Pourquoi ces trois caractéristiques structurantes de la position sociale – sexe féminin, milieu aisé et « jeune » âge –, interprétables en termes de rapports sociaux, sont-elles étroitement imbriquées dans ces syndromes ? Leur configuration dans les troubles du comportement alimentaire est atypique parmi les inégalités d’état de santé qui se manifestent habituellement au détriment des populations modestes et âgées. L’examen sociologique de ces troubles du comportement alimentaire montre que leurs soubassements ne reposent pas sur une conformation excessive aux normes et aux valeurs attendues des jeunes filles des classes aisées mais davantage sur un « usage pathologique » des normes d’excellence, en réponse aux tensions plus souvent rencontrées à cet âge.
La création de profit par les promoteurs immobiliers
Authors: Coulondre Alexandre
Published: April 2017

Cet article interroge les modes de création de profit par les acteurs économiques à travers le cas des promoteurs immobiliers. En reconstituant l’histoire d’un grand projet de centre commercial en France et en confrontant cet historique aux documents comptables prévisionnels rédigés par le promoteur, nous montrons que, contrairement à ce que prévoient les approches marxistes centrées sur l’exploitation des valeurs foncières, le profit s’inscrit avant tout dans un travail entrepreneurial de qualification du bien immobilier. Le projet est un système d’acteurs que le promoteur tente de coordonner en intégrant les attentes de ses interlocuteurs stratégiques (élus locaux, locataires, investisseurs) dans les propriétés des édifices qu’il conçoit. Ce faisant, il obtient l’implication de ces protagonistes sans s’appuyer uniquement sur une coordination par les prix qui conduirait à terme à réduire la marge bénéficiaire collectée lors du projet.
Examination of Lesbian, Gay, Bisexual, and Transgender Health Care Content in North Carolina Schools of Nursing
Authors: Cornelius Judith B. , Enweana Ijeoma , Alston Celeste Kaysha , Baldwin Dee M.
Published: April 2017

Background:

Nursing students require academic and clinical training in preparation for the increased demand for culturally competent care. One group that is in need of culturally knowledgeable health care providers is lesbian, gay, bisexual, and transgender (LGBT) individuals. The purpose of this study was to examine how LGBT health care content is integrated into North Carolina schools of nursing curricula and to examine the existence of specific LGBT policies.

Method:

A survey was mailed to 70 deans and directors of RN programs in North Carolina.

Results:

Over 90% of the schools indicated that LGBT health care issues were taught in the curricula. The majority of the content was taught as an “other” course (37%). More than two thirds of the schools devoted less than 5 hours teaching LGBT content.

Conclusion:

LGBT health care content is being taught, yet the presence of specific LGBT practice policies is basically nonexistent. [
J Nurs Educ.
2017;56(4):223–226.]
Student-Developed Simulations: Enhancing Cultural Awareness and Understanding Social Determinants of Health
Authors: Cantey Danette S. , Randolph Schenita D. , Molloy Margory A. , Carter Brigit , Cary Michael P.
Published: April 2017

Background:

National and global initiatives to address the social determinants of health (SDH) are on the rise. On a parallel trajectory, increased cultural awareness is emerging as an integral strategy to improve the understanding of these social contributions to disease states, health inequities, and health disparities.

Method:

Undergraduate nursing students developed modalities and role-played simulations as a teaching and learning strategy. The simulations demonstrated how nurses assess patients' unique needs and offer support and resources regarding patients' socioeconomic, cultural, and environmental needs.

Results:

The student-developed simulations were an interactive teaching and learning strategy that offered several benefits, such as improved interpersonal skills, learned specific nursing roles, and improved cultural awareness.

Conclusion:

Student-developed simulations are an innovative teaching strategy for improving cultural awareness and learning more about SDH. [
J Nurs Educ.
2017;56(4):243–246.]
Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division
Authors: Barr Jennifer Y. , Goodfellow Renee X. , Colgan Diana F. , Colgan John D.
Published: April 2017

B cell development in Justy mutant mice is blocked due to a precursor mRNA splicing defect that depletes the protein GON4-like (GON4L) in B cell progenitors. Genetic and biochemical studies have suggested that GON4L is a transcriptional regulator that coordinates cell division with differentiation, but its role in B cell development is unknown. To understand the function of GON4L, we characterized B cell differentiation, cell cycle control, and mitotic gene expression in GON4L-deficient B cell progenitors from Justy mice. We found that these cells established key aspects of the transcription factor network that guides B cell development and proliferation and rearranged the IgH gene locus. However, despite intact IL-7 signaling, GON4L-deficient pro-B cell stage precursors failed to undergo a characteristic IL-7–dependent proliferative burst. These cells also failed to upregulate genes required for mitotic division, including those encoding the G1/S cyclin D3 and E2F transcription factors and their targets. Additionally, GON4L-deficient B cell progenitors displayed defects in DNA synthesis and passage through the G1/S transition, contained fragmented DNA, and underwent apoptosis. These phenotypes were not suppressed by transgenic expression of prosurvival factors. However, transgenic expression of cyclin D3 or other regulators of the G1/S transition restored pro-B cell development from Justy progenitor cells, suggesting that GON4L acts at the beginning of the cell cycle. Together, our findings indicate that GON4L is essential for cell cycle progression and division during the early stages of B cell development.
Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia
Authors: Singh Shashi P. , Chand Hitendra S. , Langley Raymond J. , Mishra Neerad , Barrett Ted , Rudolph Karin , Tellez Carmen , Filipczak Piotr T. , Belinsky Steve , Saeed Ali I. , Sheybani Aryaz , Exil Vernat , Agarwal Hemant , Sidhaye Venkataramana K. , Sussan Thomas , Biswal Shyam , Sopori Mohan
Published: April 2017

Embryonic development is highly sensitive to xenobiotic toxicity and in utero exposure to environmental toxins affects physiological responses of the progeny. In the United States, the prevalence of allergic asthma (AA) is inexplicably rising and in utero exposure to cigarette smoke increases the risk of AA and bronchopulmonary dysplasia (BPD) in children and animal models. We reported that gestational exposure to sidestream cigarette smoke (SS), or secondhand smoke, promoted nicotinic acetylcholine receptor–dependent exacerbation of AA and BPD in mice. Recently, perinatal nicotine injections in rats were reported to induce peroxisome proliferator-activated receptor γ–dependent transgenerational transmission of asthma. Herein, we show that first generation and second generation progeny from gestationally SS-exposed mice exhibit exacerbated AA and BPD that is not dependent on the decrease in peroxisome proliferator-activated receptor γ levels. Lungs from these mice show strong eosinophilic infiltration, excessive Th2 polarization, marked airway hyperresponsiveness, alveolar simplification, decreased lung compliance, and decreased lung angiogenesis. At the molecular level, these changes are associated with increased RUNX3 expression, alveolar cell apoptosis, and the antiangiogenic factor GAX, and decreased expression of HIF-1α and proangiogenic factors NF-κB and VEGFR2 in the 7-d first generation and second generation lungs. Moreover, the lungs from these mice exhibit lower levels of microRNA (miR)-130a and increased levels of miR-16 and miR-221. These miRs regulate HIF-1α–regulated apoptotic, angiogenic, and immune pathways. Thus the intergenerational effects of gestational SS involve epigenetic regulation of HIF-1α through specific miRs contributing to increased incidence of AA and BPD in the progenies.
Bilateral Neuropathic Osteoarthropathy of the Shoulder due to Syringomyelia
Authors: Adiyeke Levent , Durakbaşa Mehmet Oğuz , Duymuş Tahir Mutlu
Published: April 2017

Neuropathic osteoarthropathy, which is known as Charcot osteoarthropathy, is a degenerative arthritis that develops as a result of proprioceptive and sensory innervation loss. A 47-year-old man was admitted to the emergency department of the hospital with left shoulder pain, which was ongoing and exacerbating for 5 days. Examination of the cervical region takes a crucial part in determining shoulder pathology. Palliative therapy is the prior treatment of choice as surgical therapy has potential risks in Charcot osteoarthropathy.
Uncertainty and variability in atmospheric formation of PFCAs from fluorotelomer precursors
Authors: Thackray Colin P. , Selin Noelle E.
Published: April 2017

Abstract. Perfluoroalkyl carboxylic acids (PFCAs) are environmental contaminants that are highly persistent, bio-accumulative, and have been detected along with their atmospheric precursors far from emissions sources. The importance of precursor emissions as an indirect source of PFCAs to the environment is uncertain. Modeling studies have used degradation mechanisms of differing complexities to estimate the atmospheric production of PFCAs, and these differing mechanisms lead to quantitatively different yields of PFCAs under differing atmospheric conditions. We evaluate PFCA formation with the most complete degradation mechanism to date, to our knowledge, using a box model analysis to simulate the atmospheric chemical fate of fluorotelomer precursors to long-chain PFCAs. In particular, we examine the variability in PFCA formation in different chemical environments, and estimate the uncertainty in PFCA formation due to reaction rate constants. We calculate long-chain PFCA formation theoretical maximum yields for the degradation of fluorotelomer precursor species at a representative sample of atmospheric conditions from a three-dimensional chemical transport model, and estimate uncertainties in such calculations for urban, ocean, and Arctic conditions using polynomial chaos methods. We find that atmospheric conditions farther from pollution sources have both higher capacities to form long-chain PFCAs and higher uncertainties in those capacities. Our calculations of theoretical maximum yields indicate that under typical Northern Hemisphere conditions, less than 10 % of emitted precursor may reach long-chain PFCA end products. This results in a possible upper bound of 2–50 t year−1 of long-chain PFCA (depending on quantity of emitted precursor) produced in the atmosphere via degradation of fluorotelomer products. However, transport to high-yield areas could result in higher yields. While the atmosphere is a potentially growing source of long-chain PFCAs in the Arctic, oceanic transport and interactions between the atmosphere and ocean may be relatively more important pathways to the Arctic for long-chain PFCAs.
A data–model synthesis to explain variability in calcification observed during a CO2 perturbation mesocosm experiment
Authors: Krishna Shubham , Schartau Markus
Published: April 2017

Abstract. The effect of ocean acidification on growth and calcification of the marine algae Emiliania huxleyi was investigated in a series of mesocosm experiments where enclosed water volumes that comprised a natural plankton community were exposed to different carbon dioxide (CO2) concentrations. Calcification rates observed during those experiments were found to be highly variable, even among replicate mesocosms that were subject to similar CO2 perturbations. Here, data from an ocean acidification mesocosm experiment are reanalysed with an optimality-based dynamical plankton model. According to our model approach, cellular calcite formation is sensitive to variations in CO2 at the organism level. We investigate the temporal changes and variability in observations, with a focus on resolving observed differences in total alkalinity and particulate inorganic carbon (PIC). We explore how much of the variability in the data can be explained by variations of the initial conditions and by the level of CO2 perturbation. Nine mesocosms of one experiment were sorted into three groups of high, medium, and low calcification rates and analysed separately. The spread of the three optimised ensemble model solutions captures most of the observed variability. Our results show that small variations in initial abundance of coccolithophores and the prevailing physiological acclimation states generate differences in calcification that are larger than those induced by ocean acidification. Accordingly, large deviations between optimal mass flux estimates of carbon and of nitrogen are identified even between mesocosms that were subject to similar ocean acidification conditions. With our model-based data analysis we document how an ocean acidification response signal in calcification can be disentangled from the observed variability in PIC.
Potential sources of variability in mesocosm experiments on the response of phytoplankton to ocean acidification
Authors: Moreno de Castro Maria , Schartau Markus , Wirtz Kai
Published: April 2017

Abstract. Mesocosm experiments on phytoplankton dynamics under high CO2 concentrations mimic the response of marine primary producers to future ocean acidification. However, potential acidification effects can be hindered by the high standard deviation typically found in the replicates of the same CO2 treatment level. In experiments with multiple unresolved factors and a sub-optimal number of replicates, post-processing statistical inference tools might fail to detect an effect that is present. We propose that in such cases, data-based model analyses might be suitable tools to unearth potential responses to the treatment and identify the uncertainties that could produce the observed variability. As test cases, we used data from two independent mesocosm experiments. Both experiments showed high standard deviations and, according to statistical inference tools, biomass appeared insensitive to changing CO2 conditions. Conversely, our simulations showed earlier and more intense phytoplankton blooms in modeled replicates at high CO2 concentrations and suggested that uncertainties in average cell size, phytoplankton biomass losses, and initial nutrient concentration potentially outweigh acidification effects by triggering strong variability during the bloom phase. We also estimated the thresholds below which uncertainties do not escalate to high variability. This information might help in designing future mesocosm experiments and interpreting controversial results on the effect of acidification or other pressures on ecosystem functions.
Impact of LUCC on streamflow based on the SWAT model over the Wei River basin on the Loess Plateau in China
Authors: Wang Hong , Sun Fubao , Xia Jun , Liu Wenbin
Published: April 2017

Abstract. Under the Grain for Green Project in China, vegetation recovery construction has been widely implemented on the Loess Plateau for the purpose of soil and water conservation. Now it is becoming controversial whether the recovery construction involving vegetation, particularly forest, is reducing the streamflow in the rivers of the Yellow River basin. In this study, we chose the Wei River, the largest branch of the Yellow River, with revegetated construction area as the study area. To do that, we apply the widely used Soil and Water Assessment Tool (SWAT) model for the upper and middle reaches of the Wei River basin. The SWAT model was forced with daily observed meteorological forcings (1960–2009) calibrated against daily streamflow for 1960–1969, validated for the period of 1970–1979, and used for analysis for 1980–2009. To investigate the impact of LUCC (land use and land cover change) on the streamflow, we firstly use two observed land use maps from 1980 and 2005 that are based on national land survey statistics merged with satellite observations. We found that the mean streamflow generated by using the 2005 land use map decreased in comparison with that using the 1980 one, with the same meteorological forcings. Of particular interest here is that the streamflow decreased on agricultural land but increased in forest areas. More specifically, the surface runoff, soil flow, and baseflow all decreased on agricultural land, while the soil flow and baseflow of forest areas increased. To investigate that, we then designed five scenarios: (S1) the present land use (1980) and (S2) 10 %, (S3) 20 %, (S4) 40 %, and (S5) 100 % of agricultural land that was converted into mixed forest. We found that the streamflow consistently increased with agricultural land converted into forest by about 7.4 mm per 10 %. Our modeling results suggest that forest recovery construction has a positive impact on both soil flow and baseflow by compensating for reduced surface runoff, which leads to a slight increase in the streamflow in the Wei River with the mixed landscapes on the Loess Plateau that include earth–rock mountain area.
Two dimensional finite element estimation of calcium ions in presence fo NCX and Buffers in Astrocytes
Authors: Jha Brajesh Kumar , Jha Amrita
Published: April 2017

Sodium calcium exchanger (NCX) plays effective role in signal transduction in most of the nerve cells like neuron, astrocytes. Sodium ion affects the cytosolic calcium concentration label in Astrocytes via various channels. This affects the movement of the nerve impulse from one cell to other cell. In this paper two dimensional model is developedin the form of diffusion equation to study the effect of NCX in presence and negligence of buffer in Astrocytes. Finite element method is employed to solve the problem and simulated in Matlab to estimate the affect of various parameter like flux, diffusion coefficient, buffer concentration, etc.
Measuring Entrepreneurial Readiness among Youth in Pakistan through Theory of Planned Behavior (TPB) Based Approach
Authors: Zulfiqar Salman , Asmi Fahad , Chandia Khurram Ejaz , Sarwar Binesh , Aziz Saira
Published: April 2017

Purpose: The purpose of this paper is to measure entrepreneurial readiness among youth in Pakistan, through TPB based approach.Design/Methodology/Approach: The data were collected from people who work in different fields like banking sector and education sector of Pakistan. In total 380 questionnaires were circulated among people through the online survey. The IBM Statistics SPSS 23.0 was used to perform statistical analysis.Findings: The research finds that entrepreneurial attitude, social norms and perceived behavioral control have significant positive effect on entrepreneurial readiness among youngsters. Moreover, research shows that entrepreneurial knowledge has significant positive impact on entrepreneurial attitude, social norm and perceived social normResearch Limitations: Research population is the main limitation in this research, small sample size was selected and results were compiled on the basis of this sample size. Originality/value: In these existing economic crises of Pakistan, “Developing Entrepreneurs” is one of the important ways to boost financial growth. Youngsters always play an important role in the development of economy and have potential to become future entrepreneurs. Research to check readiness among youngsters to become entrepreneurs in Pakistan is limited. This research has added value in both theory and practice by identifying the factors that can develop students’ intentions to become entrepreneurs.
Editorial
Authors: Caregnato Rita Catalina  Aquino
Published: April 2017

Editorial
Indicadores de qualidade em enfermagem com ênfase no centro cirúrgico: revisão integrativa da literatura
Authors: Amaral Juliana Aparecida Baldo , Spiri Wilza Carla , Bocchi Silvia Cristina Mangini
Published: April 2017

Objetivo: Analisar as produções nacional e internacional dos indicadores de qualidade em Enfermagem no Centro Cirúrgico. Método: Revisão integrativada literatura de 2009 a 2016 de artigos indexados nas bases de dados: Literatura Latino‑Americana e do Caribe em Ciências da Saúde, Scientific Electronic LibraryOnline e US National Library of Medicine. A amostra final foi composta por 17 artigos. Resultados: Houve predominância das publicações nacionais, em 2013, realizadaspor enfermeiros mestres, com abordagem quantitativa. Os temas dessas foram: importância, confiabilidade e benefícios dos indicadores de qualidade para ogerenciamento da assistência de Enfermagem; principais dificuldades quanto ao uso dos indicadores; sistema informatizado para coleta de dados dos indicadores evisão dos enfermeiros a respeito do uso dessa ferramenta de qualidade. Conclusão: Foram observados os benefícios e as principais dificuldades referentes à utilizaçãodos indicadores de qualidade para o Centro Cirúrgico. No entanto, a avaliação de desempenho do Centro Cirúrgico por meio de indicadores ainda é pouco utilizada.