bluuebunny/crossref_metadata_2025 huggingface dataset:
Calibration of multi-layered probes with low/high magnetic moments
Authors: Panchal Vishal , Corte-León Héctor , Gribkov Boris , Rodriguez Luis Alfredo , Snoeck Etienne , Manzin Alessandra , Simonetto Enrico , Vock Silvia , Neu Volker , Kazakova Olga
Published: July 2017

We present a comprehensive method for visualisation and quantification of the magnetic stray field of magnetic force microscopy (MFM) probes, applied to the particular case of custom-made multi-layered probes with controllable high/low magnetic moment states. The probes consist of two decoupled magnetic layers separated by a non-magnetic interlayer, which results in four stable magnetic states: ±ferromagnetic (FM) and ±antiferromagnetic (A-FM). Direct visualisation of the stray field surrounding the probe apex using electron holography convincingly demonstrates a striking difference in the spatial distribution and strength of the magnetic flux in FM and A-FM states. In situ MFM studies of reference samples are used to determine the probe switching fields and spatial resolution. Furthermore, quantitative values of the probe magnetic moments are obtained by determining their real space tip transfer function (RSTTF). We also map the local Hall voltage in graphene Hall nanosensors induced by the probes in different states. The measured transport properties of nanosensors and RSTTF outcomes are introduced as an input in a numerical model of Hall devices to verify the probe magnetic moments. The modelling results fully match the experimental measurements, outlining an all-inclusive method for the calibration of complex magnetic probes with a controllable low/high magnetic moment.
NuBBEDB: an updated database to uncover chemical and biological information from Brazilian biodiversity
Authors: Pilon Alan C. , Valli Marilia , Dametto Alessandra C. , Pinto Meri Emili F. , Freire Rafael T. , Castro-Gamboa Ian , Andricopulo Adriano D. , Bolzani Vanderlan S.
Published: July 2017

The intrinsic value of biodiversity extends beyond species diversity, genetic heritage, ecosystem variability and ecological services, such as climate regulation, water quality, nutrient cycling and the provision of reproductive habitats it is also an inexhaustible source of molecules and products beneficial to human well-being. To uncover the chemistry of Brazilian natural products, the Nuclei of Bioassays, Ecophysiology and Biosynthesis of Natural Products Database (NuBBEDB) was created as the first natural product library from Brazilian biodiversity. Since its launch in 2013, the NuBBEDB has proven to be an important resource for new drug design and dereplication studies. Consequently, continuous efforts have been made to expand its contents and include a greater diversity of natural sources to establish it as a comprehensive compendium of available biogeochemical information about Brazilian biodiversity. The content in the NuBBEDB is freely accessible online (https://nubbe.iq.unesp.br/portal/nubbedb.html) and provides validated multidisciplinary information, chemical descriptors, species sources, geographic locations, spectroscopic data (NMR) and pharmacological properties. Herein, we report the latest advancements concerning the interface, content and functionality of the NuBBEDB. We also present a preliminary study on the current profile of the compounds present in Brazilian territory.
Environmental influence on Pristionchus pacificus mouth form through different culture methods
Authors: Werner Michael S. , Sieriebriennikov Bogdan , Loschko Tobias , Namdeo Suryesh , Lenuzzi Masa , Dardiry Mohannad , Renahan Tess , Sharma Devansh Raj , Sommer Ralf J.
Published: July 2017

Environmental cues can impact development to elicit distinct phenotypes in the adult. The consequences of phenotypic plasticity can have profound effects on morphology, life cycle, and behavior to increase the fitness of the organism. The molecular mechanisms governing these interactions are beginning to be elucidated in a few cases, such as social insects. Nevertheless, there is a paucity of systems that are amenable to rigorous experimentation, preventing both detailed mechanistic insight and the establishment of a generalizable conceptual framework. The mouth dimorphism of the model nematode Pristionchus pacificus offers the rare opportunity to examine the genetics, genomics, and epigenetics of environmental influence on developmental plasticity. Yet there are currently no easily tunable environmental factors that affect mouth-form ratios and are scalable to large cultures required for molecular biology. Here we present a suite of culture conditions to toggle the mouth-form phenotype of P. pacificus. The effects are reversible, do not require the costly or labor-intensive synthesis of chemicals, and proceed through the same pathways previously examined from forward genetic screens. Different species of Pristionchus exhibit different responses to culture conditions, demonstrating unique gene-environment interactions, and providing an opportunity to study environmental influence on a macroevolutionary scale.
Chemotherapy treatment induces an increase of autophagy in the luminal breast cancer cell MCF7, but not in the triple-negative MDA-MB231
Authors: Garbar Christian , Mascaux Corinne , Giustiniani Jérôme , Merrouche Yacine , Bensussan Armand
Published: July 2017

Autophagy is one of the chemotherapy resistance mechanisms in breast cancer. The aim of this study was to determine the level of recruitment of the autophagy pathway in the triple-negative breast cancer (TNBC) cell line MDA-MB231 compared with that in the control luminal breast cancer cell line MCF7 before and after treatment with chemotherapy drugs. Furthermore, we investigated the relationship between autophagy and EGFR, MUC1 and IL17-receptors as activators of autophagy. Immunohistochemistry was performed in cell culture blocks using LC3b, MUC1-C, EGFR, IL17A, IL17-RA and IL17-RB antibodies. We found that the basal autophagy level in MDA-MB231 was high, whereas it was low in MCF7. However, in contrast to MDA-MB231, the autophagy level was increased in MCF7 upon treatment with chemotherapy agents. Interestingly, we observed that the expression levels of MUC1-C, EGFR, IL17-RA, and IL17-RB were not modified by the same treatments. Furthermore, the chemotherapy treatments did not increase autophagy in TNBC cells without affecting the expression levels of MUC1-C, EGFR, IL17-RA or IL17-RB.
Broadband Silicon-On-Insulator directional couplers using a combination of straight and curved waveguide sections
Authors: Chen George F. R. , Ong Jun Rong , Ang Thomas Y. L. , Lim Soon Thor , Png Ching Eng , Tan Dawn T. H.
Published: July 2017

Broadband Silicon-On-Insulator (SOI) directional couplers are designed based on a combination of curved and straight coupled waveguide sections. A design methodology based on the transfer matrix method (TMM) is used to determine the required coupler section lengths, radii, and waveguide cross-sections. A 50/50 power splitter with a measured bandwidth of 88 nm is designed and fabricated, with a device footprint of 20 μm × 3 μm. In addition, a balanced Mach-Zehnder interferometer is fabricated showing an extinction ratio of >16 dB over 100 nm of bandwidth.
Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D
Authors: Wang Pin , Wang Luanluan , Chen Long , Sun Xiulian
Published: July 2017

Dual-specificity tyrosine–phosphorylation regulated kinase 1A (DYRK1A) is localized in the Down syndrome critical region of chromosome 21. As a candidate gene responsible for learning defects associated with Down syndrome and Alzheimer’s disease (AD), DYRK1A has been implied to play pivotal roles in cell proliferation and brain development. MEF2D, a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors, was proved to be in control of neuronal cell differentiation and development. Here we demonstrated that MEF2D could upregulate DYRK1A gene expression through specific activation of DYRK1A isoform 5 gene transcription. A MEF2D responsive element from −268 to −254 bp on promoter region of DYRK1A isoform 5 was identified and confirmed by luciferase assay, electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChIP). The coordinated expression of DYRK1A and MEF2D in mouse brain development indicated a possibility of the cross-interaction of these two genes during neurodevelopment. The DYRK1A kinase activity was also affected by MEF2D’s transcriptional regulation of DYRK1A. Therefore, the molecular regulation of DYRK1A by MEF2D further supported their involvement in neurodevelopment.
FT-IR-based method for rutin, quercetin and quercitrin quantification in different buckwheat (Fagopyrum) species
Authors: Kokalj Ladan Meta , Straus Janka , Tavčar Benković Eva , Kreft Samo
Published: July 2017

The present study explores an alternative method for antioxidants determination in buckwheat (Fagopyrum) samples. Buckwheat contains different amounts of the antioxidants rutin, quercetin and quercitrin in different plant parts. Buckwheat seeds are most commonly used as food; however, preparations from the herb can also be used as a rich source of rutin. Infrared spectroscopy was used for individual and sum quantification of rutin, quercetin and quercitrin in whole and ground flowers and leaves of seven different buckwheat species. Correlation coefficients R of calibration and independent validation set for rutin, quercetin and quercitrin were 1.00 and 0.98, 0.94 and 0.99, 0.99 and 0.95, respectively. Some of the developed models had accuracy comparable to the reference HPLC method. Additionally many different parameters that give an important insight into the FTIR technique are discussed (different plant parts, whole and ground untreated samples, 3 different resolutions, 7 spectra pre-treatments, using individual or averaged spectra, reducing spectral data input, considering additional non-spectral data). The implemented technique used no sample preparation, is non-destructive and uses very little amounts of sample. Result show that infrared spectroscopy can be a fast and environmentally friendly alternative technique for routine analysis of main flavonoids in aerial parts of buckwheat.
Liquid metal amoeba with spontaneous pseudopodia formation and motion capability
Authors: Hu Liang , Yuan Bin , Liu Jing
Published: July 2017

The unique motion of amoeba with a deformable body has long been an intriguing issue in scientific fields ranging from physics, bionics to mechanics. So far, most of the currently available artificial machines are still hard to achieve the complicated amoeba-like behaviors including stretching pseudopodia. Here through introducing a multi-materials system, we discovered a group of very unusual biomimetic amoeba-like behaviors of self-fueled liquid gallium alloy on the graphite surface immersed in alkaline solution. The underlying mechanisms were discovered to be the surface tension variations across the liquid metal droplet through its simultaneous electrochemical interactions with aluminum and graphite in the NaOH electrolyte. This finding would shed light on the packing and the structural design of future soft robots owning diverse deformation capability. Moreover, this study related the physical transformation of a non-living LM droplet to the life behavior of amoeba in nature, which is inspiring in human’s pursuit of advanced biomimetic machine.
Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies
Authors: Sennari Goh , Saito Ryo , Hirose Tomoyasu , Iwatsuki Masato , Ishiyama Aki , Hokari Rei , Otoguro Kazuhiko , Ōmura Satoshi , Sunazuka Toshiaki
Published: July 2017

Divergent synthesis of antimalarial troponoids, including naturally occurring compounds, some of which were identified and isolated by our group, has been achieved utilizing the total synthetic route of puberulic acid. Structure-activity relationships of natural products and simple troponoids inspired us to explore more detailed properties of this class of compounds. Access to new derivatives was facilitated through intermediate compounds generated during the total synthesis of puberulic acid by a stepwise oxidation-aromatization sequence to provide 7-hydroxytropolones and bromination for conversion of the carboxylic acid moiety. The first total synthesis of viticolin A, as well as the synthesis of different methyl-substituted derivatives, has also been achieved. In vitro antimalarial activity and cytotoxicity of novel derivatives were evaluated and fundamental information to facilitate the discovery of more promising antimalarials was obtained.
A Post-Processing Method for Three-Dimensional Electrical Impedance Tomography
Authors: Martin Sébastien , Choi Charles T. M.
Published: July 2017

Electrical impedance tomography is a modern biomedical imaging method. Its goal is to image the electrical properties of human tissues. This approach is safe for the patient’s health, is non-invasive and has no known hazards. However, the approach suffers from low accuracy. Linear inverse solvers are commonly used in medical applications, as they are strongly robust to noise. However, linear methods can give only an approximation of the solution that corresponds to a linear perturbation from an initial estimate. This paper proposes a novel reconstruction process. After applying a linear solver, the conductivity distribution is post-processed with a nonlinear algorithm, with the aim of reproducing the abrupt change in conductivity at the boundaries between tissues or organs. The results are used to compare the proposed method with three other widely used methods. The proposed method offers higher quality images and a higher robustness to noise, and significantly reduces the error associated with image reconstruction.
Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients
Authors: Xiao Fei-Yan , Luo Jian-Quan , Liu Min , Chen Bi-Lian , Cao Shan , Liu Zhao-Qian , Zhou Hong-Hao , Zhou Gan , Zhang Wei
Published: July 2017

Carboxylesterase 1 (CES1) hydrolyzes the prodrug clopidogrel to an inactive carboxylic acid metabolite. The effects of CES1 S75N (rs2307240,C>T) on clopidogrel response among 851 acute coronary syndrome patients who came from the north, central and south of China were studied. The occurrence ratios of each endpoint in the CC group were significantly higher than in the CT + TT group for cerebrovascular events (14% vs 4.8%, p < 0.001, OR = 0.31), acute myocardial infarction (15.1% vs 6.1%, p < 0.001, OR = 0.37) and unstable angina (62.8% vs 37.7%, p < 0.001, OR = 0.36). The results showed that there was a significant association between CES1 S75N (rs2307240) and the outcome of clopidogrel therapy. Moreover, the frequency of the T allele of rs2307240 in acute coronary syndrome patients (MAF = 0.22) was more than four times higher than that in the general public (MAF = 0.05).
Separate requirements for detection and perceptual stability of motion in interocular suppression
Authors: Ananyev Egor , Penney Trevor B. , Hsieh Po-Jang
Published: July 2017

In interocular masking, a stimulus presented to one eye (the mask) is made stronger in order to suppress from awareness the target stimulus presented to the other eye. We investigated whether matching the features of the target and the mask would lead to more effective suppression (feature-selective suppression), or not (i.e., non-selective suppression). To control the temporal characteristics of the stimuli, we used a dynamic interocular mask to suppress a moving target, and found that neither matching speed nor pattern of motion led to more effective suppression. Instead, a faster target was detected faster, regardless of the mask type or speed, while a relatively slow (about 1°/s) mask was more perceptually stable (i.e., maintained suppression longer) in a non-selective fashion. While the requirement for target detectability, i.e., salience, is well characterized, relatively little attention is given to the factors that make a mask percept more perceptually stable. Based on these results, we argue that there are separate requirements for detection and perceptual stability.
Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency
Authors: Hos Deniz , Bukowiecki Anne , Horstmann Jens , Bock Felix , Bucher Franziska , Heindl Ludwig M. , Siebelmann Sebastian , Steven Philipp , Dana Reza , Eming Sabine A. , Cursiefen Claus
Published: July 2017

Lymphangiogenesis is essential for fluid homeostasis in vascularized tissues. In the normally avascular cornea, however, pathological lymphangiogenesis mediates diseases like corneal transplant rejection, dry eye disease, and allergy. So far, a physiological role for lymphangiogenesis in a primarily avascular site such as the cornea has not been described. Using a mouse model of perforating corneal injury that causes acute and severe fluid accumulation in the cornea, we show that lymphatics transiently and selectively invade the cornea and regulate the resolution of corneal edema. Pharmacological blockade of lymphangiogenesis via VEGFR-3 inhibition results in increased corneal thickness due to delayed drainage of corneal edema and a trend towards prolonged corneal opacification. Notably, lymphatics are also detectable in the cornea of a patient with acute edema due to spontaneous Descemet´s (basement) membrane rupture in keratoconus, mimicking this animal model and highlighting the clinical relevance of lymphangiogenesis in corneal fluid homeostasis. Together, our findings provide evidence that lymphangiogenesis plays an unexpectedly beneficial role in the regulation of corneal edema and transparency. This might open new treatment options in blinding diseases associated with corneal edema and transparency loss. Furthermore, we demonstrate for the first time that physiological lymphangiogenesis also occurs in primarily avascular sites.
Phenylalanine ammonia-lyase2.1 contributes to the soybean response towards Phytophthora sojae infection
Authors: Zhang Chuanzhong , Wang Xin , Zhang Feng , Dong Lidong , Wu Junjiang , Cheng Qun , Qi Dongyue , Yan Xiaofei , Jiang Liangyu , Fan Sujie , Li Ninghui , Li Dongmei , Xu Pengfei , Zhang Shuzhen
Published: July 2017

Phytophthora root and stem rot of soybean [Glycine max(L.) Merr.] caused byPhytophthora sojaeis a destructive disease worldwide. Phenylalanine ammonia-lyase (PAL) is one of the most extensively studied enzymes related to plant responses to biotic and abiotic stresses. However, the molecular mechanism of PAL in soybean in response toP.sojaeis largely unclear. Here, we characterize a novel member of the soybean PAL gene family,GmPAL2.1, which is significantly induced byP.sojae. Overexpression and RNA interference analysis demonstrates that GmPAL2.1 enhances resistance toP.sojaein transgenic soybean plants. In addition, the PAL activity inGmPAL2.1-OX transgenic soybean is significantly higher than that of non-transgenic plants after infection withP.sojae, while that inGmPAL2.1-RNAi soybean plants is lower. Further analyses show that the daidzein, genistein and salicylic acid (SA) levels and the relative content of glyceollins are markedly increased inGmPAL2.1-OX transgenic soybean. Taken together, these results suggest the important role of GmPAL2.1 functioning as a positive regulator in the soybean response toP.sojaeinfection, possibly by enhancing the content of glyceollins, daidzein, genistein and SA.
Divergent co-transcriptomes of different host cells infected with Toxoplasma gondii reveal cell type-specific host-parasite interactions
Authors: Swierzy Izabela J. , Händel Ulrike , Kaever Alexander , Jarek Michael , Scharfe Maren , Schlüter Dirk , Lüder Carsten G. K.
Published: July 2017

The apicomplexan parasite Toxoplasma gondii infects various cell types in avian and mammalian hosts including humans. Infection of immunocompetent hosts is mostly asymptomatic or benign, but leads to development of largely dormant bradyzoites that persist predominantly within neurons and muscle cells. Here we have analyzed the impact of the host cell type on the co-transcriptomes of host and parasite using high-throughput RNA sequencing. Murine cortical neurons and astrocytes, skeletal muscle cells (SkMCs) and fibroblasts differed by more than 16,200 differentially expressed genes (DEGs) before and after infection with T. gondii. However, only a few hundred of them were regulated by infection and these largely diverged in neurons, SkMCs, astrocytes and fibroblasts indicating host cell type-specific transcriptional responses after infection. The heterogeneous transcriptomes of host cells before and during infection coincided with ~5,400 DEGs in T. gondii residing in different cell types. Finally, we identified gene clusters in both T. gondii and its host, which correlated with the predominant parasite persistence in neurons or SkMCs as compared to astrocytes or fibroblasts. Thus, heterogeneous expression profiles of different host cell types and the parasites’ ability to adapting to them may govern the parasite-host cell interaction during toxoplasmosis.
Interfacial growth of a metal–organic framework (UiO-66) on functionalized graphene oxide (GO) as a suitable seawater adsorbent for extraction of uranium(vi)
Authors: Yang Peipei , Liu Qi , Liu Jingyuan , Zhang Hongsen , Li Zhanshuang , Li Rumin , Liu Lianhe , Wang Jun
Published: July 2017

A suitable seawater adsorbent for extraction of uranium(vi) with a removal rate of up to 80%.
NiZn double hydroxide nanosheet-anchored nitrogen-doped graphene enriched with the γ-NiOOH phase as an activity modulated water oxidation electrocatalyst
Authors: Nadeema Ayasha , Dhavale Vishal M. , Kurungot Sreekumar
Published: July 2017

We report a facile synthesis of an open, thin layered and γ-NiOOH enriched NiZn-double hydroxide/nitrogen doped graphene composite catalyst exhibiting robust OER activity.
Voltage-activated transport of ions through single-walled carbon nanotubes
Authors: Yazda Khadija , Tahir Saïd , Michel Thierry , Loubet Bastien , Manghi Manoel , Bentin Jeremy , Picaud Fabien , Palmeri John , Henn François , Jourdain Vincent
Published: July 2017

SWCNTs of diameter of 1.2 to 2 nm can show a linear or a voltage-activatedI–Vdependence.
Poly(ε-caprolactone) nanocapsule carriers with sustained drug release: single dose for long-term glaucoma treatment
Authors: Lee Chih-Hung , Li Yu-Jia , Huang Chih-Ching , Lai Jui-Yang
Published: July 2017

The loading of pilocarpine in the poly(ε-caprolactone) nanocapsules exhibited a sustained drug release profile and effective pharmacological responses for glaucoma treatment.
Nanostructured materials on 3D nickel foam as electrocatalysts for water splitting
Authors: Chaudhari Nitin K. , Jin Haneul , Kim Byeongyoon , Lee Kwangyeol
Published: July 2017

This review addresses recent developments in earth-abundant electrocatalysts directly synthesized on 3D nickel foam as electrodes for electrochemical water electrolysis.
Facile preparation of nitrogen-doped graphene as an efficient oxygen reduction electrocatalyst
Authors: Gao Xiaochun , Wang Liwei , Ma Jizhen , Wang Yueqing , Zhang Jintao
Published: July 2017

Nitrogen doped graphene with good catalytic activity to oxygen reduction is preparedviathe co-precipitation of graphene oxide and melamine in the presence of inorganic acids and a subsequent pyrolysis process, endowing the fabricated Zn–air battery with high power density and good stability.
PhI(OAc)2-mediated dialkoxylation of 4-aminostyrenes through a dearomatization process under metal-free conditions
Authors: Wang Weiyi , He Qiuqin , Fan Renhua
Published: July 2017

A PhI(OAc)2-mediated dialkoxylation of 4-aminostyrenes has been developed to afford 2,3-disubstituted 1,4-dioxane or 1,2-dimethoxyethane derivatives.
Color conversion of the magnetically separable Al/Fe oxide RNGO in the selective oxidation of benzyl alcohol induced the observation of its morphology change
Authors: Li Qichen , Zhang Lingling , Wang Xiaozhong , Xu Gang , Chen Yingqi , Dai Liyan
Published: July 2017

The morphology changed in accordance with the catalytic performance through the observation of color variation during the lifetime test: with a chaotic layout and a comparable inferior catalytic activity initially, while a waffle or pastry state and a relatively superior activity in the prime time performance.
Microvesicle release and micellar attack as the alternative mechanisms involved in the red-blood-cell-membrane solubilization induced by arginine-based surfactants
Authors: Fait M. Elisa , Hermet Melisa , Comelles Francesc , Clapés Pere , Alvarez H. Ariel , Prieto Eduardo , Herlax Vanesa , Morcelle Susana R. , Bakás Laura
Published: July 2017

Two novel arginine-based surfactants, Bz-Arg-NHC10 and Bz-Arg-NHC12, were characterized with respect to surface properties and their interaction with human red-blood-cell (HRBC) membranes.
An experimental study on the effects of freeze–thaw cycles on phosphorus adsorption–desorption processes in brown soil
Authors: Wang Qingzhi , Liu Jiankun , Wang Lingqing
Published: July 2017

Freeze–thaw cycles (FTCs) can strongly influence the physical and chemical properties of soils in cold regions, which can in turn affect the adsorption–desorption characteristics of phosphorus (P) in the soil.
Remarkable lignin degradation in paper wastewaters over Fe2O3/γ-Al2O3 catalysts using the catalytic wet peroxide oxidation method
Authors: Wu Di , Hu Zhen , Zhang Xuqi , Zhang Cuiran , Sun Kai , Lu Shuxiang
Published: July 2017

Heterogeneous catalytic wet peroxide oxidation (CWPO) has been found to be one of the most effective approaches for the degradation of toxic and biore factory wastewater.
Microbially induced calcium carbonate precipitation driven by ureolysis to enhance oil recovery
Authors: Wu Jun , Wang Xian-Bin , Wang Hou-Feng , Zeng Raymond J.
Published: July 2017

Microbially induced calcium carbonate precipitation was used to improve poor volumetric sweep efficiency of water and enhance oil recovery.
Notable in situ surface transformation of Cu2O nanomaterials leads to dramatic activity enhancement for CO oxidation
Authors: Zhao Dan , Tu Chang-Man , Hu Xue-Jing , Zhang Ning
Published: July 2017

Irrespective of the initial states, the pure Cu(i) surface of Cu2O would in situ transform into a stable Cu(i)–Cu(ii) composite surface during the first catalytic run of CO oxidation, resulting in dramatic activity enhancement.
Stability of UV/ozone-treated thermoplastics under different storage conditions for microfluidic analytical devices
Authors: Lin Tung-Yi , Pfeiffer Trey T. , Lillehoj Peter B.
Published: July 2017

Hydrophobic recovery of UVO-treated plastics can be inhibited by storing them in dehumidified or vacuum conditions.
Correction: Chemoselective dehydrogenative esterification of aldehydes and alcohols with a dimeric rhodium(ii) catalyst
Authors: Cheng Junjie , Zhu Meijuan , Wang Chao , Li Junjun , Jiang Xue , Wei Yawen , Tang Weijun , Xue Dong , Xiao Jianliang
Published: July 2017

Correction for ‘Chemoselective dehydrogenative esterification of aldehydes and alcohols with a dimeric rhodium(ii) catalyst’ by Junjie Cheng et al., Chem. Sci., 2016, 7, 4428–4434.
Interfacial rheological properties of self-assembling biopolymer microcapsules
Authors: Xie Kaili , de Loubens Clément , Dubreuil Frédéric , Gunes Deniz Z. , Jaeger Marc , Léonetti Marc
Published: July 2017

Self-assembling biopolymer microcapsules present a wealth of mechanical properties that were characterized in extensional flow.
Green-low-cost rechargeable aqueous zinc-ion batteries using hollow porous spinel ZnMn2O4as the cathode material
Authors: Wu Xianwen , Xiang Yanhong , Peng Qingjing , Wu Xiangsi , Li Yehua , Tang Fang , Song Runci , Liu Zhixiong , He Zeqiang , Wu Xianming
Published: July 2017

Deficient spinel ZnMn2O4with a hollow porous structure was prepared through a solvothermal carbon template dispersed by polyvinyl pyrrolidone.
Hydrogenation of silicene on Ag(111) and formation of half-silicane
Authors: Wei Wei , Dai Ying , Huang Baibiao
Published: July 2017

Uniformly ordered and reversible hydrogenation may be useful for tuning the properties of silicene and for controllable hydrogen storage.
Hierarchical hollow nanofiber networks for high-performance hybrid direct carbon fuel cells
Authors: Liu Jia , Yuan Hong , Qiao Jinshuo , Feng Jie , Xu Chunming , Wang Zhenhua , Sun Wang , Sun Kening
Published: July 2017

Hierarchical, hollow nanofibers of Ce0.6Mn0.3Fe0.1O2were designed as an efficient anode for hybrid direct carbon fuel cells, which displayed superior electrochemical performance.
A sulfur–FePO4–C nanocomposite cathode for stable and anti-self-discharge lithium–sulfur batteries
Authors: Pang Ying , Wen Yunping , Li Wangyu , Sun Yunhe , Zhu Tiancheng , Wang Yonggang , Xia Yongyao
Published: July 2017

A S–FePO4–C nanocomposite is designed as a cathode material for Li–S batteries, which exhibits highly stable and typical anti-self-discharge behavior.
Bromine and nitrogen co-doped tungsten nanoarrays to enable hydrogen evolution at all pH values
Authors: Li Qun , Han Ce , Ma Xiao , Wang Dewen , Xing Zhicai , Yang Xiurong
Published: July 2017

Introducing Br and N into metallic tungsten nanoarrays produces a corrosion resistance in W/BrN with high performance for HER at all pH values. The excellent activity, enhanced electrical conductivity, as well as large turnover frequency of W/BrN are attributed to the codoping of Br and N.
Monolithic Bi1.5Sb0.5Te3 ternary alloys with a periodic 3D nanostructure for enhancing thermoelectric performance
Authors: Hong Seokkyoon , Park Junyong , Jeon Seong Gi , Kim Kisun , Park Sun Hwa , Shin Ho Sun , Kim Bumsoo , Jeon Seokwoo , Song Jae Yong
Published: July 2017

We newly propose a periodic 3D nanostructure to reduce the thermal conductivity of Bi1.5Sb0.5Te3 ternary alloys, which results in a greatly enhanced figure of merit (>50%).
Substrate integrated‐based Fermi‐Dirac multibeam antenna for mmWave applications
Authors: Gupta S. , Briqech Z. , Sebak A.R.
Published: July 2017

A multi‐feed Ka‐band sin‐shape corrugation antipodal Fermi‐linear tapered slot antenna subarray is presented. The proposed prototype consists of four antenna elements excited by multimode beamforming network as an efficient method to perform beamforming operation without any use of couplers and phase shifters. It is implemented using substrate integrated waveguide technology. The four‐element subarray has a measured gain of 11.45–13.86 dB along with beam scanning range of 24° and a narrow beamwidth (11.85°–13.05°) over 29–36 GHz. The measured mutual coupling between the four antenna ports is better than – 20 dB over the frequency range 29–36 GHz. The proposed multibeam antenna can be implemented for applications related to target tracking and imaging systems.
Heuristic optimisation for network restoration and expansion in compliance with the single‐contingency policy
Authors: Thurner Leon , Scheidler Alexander , Probst Alexander , Braun Martin
Published: July 2017

Since failure of high‐ to medium‐voltage (MV) transformers affect a large number of consumers, they are usually built with a redundancy to guarantee service restoration in the case of a single contingency. The redundancy can be provided by a backup transformer or by transferring the load to a neighbouring substation in case of failure. While a load transfer allows for more efficient use of transformers in normal operation, it also requires the MV network to be dimensioned with redundant transmission capability for the contingency case. In this study, the authors present their approach to determine if it is profitable in the long term to remove a backup transformer in intrinsically safe substations and handle resupply with load transfer to neighbouring substations instead. To this end, they compare the cost of the necessary network expansion to the costs of a backup transformer. They introduce an iterated local search algorithm for the calculation of emergency switching plans as well as expansion of the MV network. The methodology is applied to a large real MV network group, where reinforcing the network to allow a load transfer is cost efficient compared with the existing backup transformer in three of four substations.
Novel angular‐independent higher order band‐stop frequency selective surface for X‐band applications
Authors: Kocakaya Aybike , Çakır Gonca
Published: July 2017

A higher order miniaturised band‐stop frequency selective surface (FSS) with angular stability performance for X‐band applications is presented in this study. The miniaturisation has been achieved by incurving the arms of conventional cross dipole shape inside. The unit cell size of FSS is diminished up to 75% compared to cross dipole FSS operating at the same resonant frequencies. Moreover, the presented FSS is designed to exhibit stable angular performance for incident angles up to about 60° for TE‐ and TM‐polarised waves. The maximum relative frequency deviation is 1.28% with respect to different angles of incidence. Although the designed FSS consists of two layers, higher order and sharp roll‐off filter characteristics have been obtained. The simulation of the proposed FSS is performed with the CST MWS. To verify the simulation results, the presented FSS is measured and a good match between the experimental and simulation results are obtained.
Safety and Effectiveness of Transarterial Embolization for Blunt Abdominal Injuries: A Multicenter Study with Review of Literature
Authors: Cherian Mathew , Kalyanpur Tejas , Murali Krishna , Garg Ashwin , Munde Yadav , Yadav Ajit , Gupta Arun , Dalai Sibasankar , Desai Paresh , Jadhav Prithviraj
Published: July 2017

Aims To evaluate the safety and effectiveness of transarterial embolization for blunt abdominal trauma in patients without the imaging signs of peritonitis or bowel injury.

Materials and Methods A total of 45 patients (41 males and 4 females; mean age: 32.15) were studied, of which 48% were hemodynamically unstable. All patients underwent multidetector computed tomography prior to selective angiography and embolization. Outcomes were considered as favorable if embolization was successful in achieving hemostasis. The frequency of complications, mortality rates, and duration of hospital stay were calculated.

Results Embolization was successful in achieving hemostasis in all patients. None of the patients required surgery to achieve hemostasis after embolization. The overall mortality rate was 13.3% and none related to persistent bleeding. The mean intensive care unit stay was 5.6 days and the median was 3.5 days. Only one patient required continued blood transfusion of more than 10 units after embolization. No major complications were encountered except for one patient who required hemodialysis for acute renal injury related to embolization procedure.

Conclusion Transarterial embolization is very effective in treating bleeding related to blunt abdominal trauma even in hemodynamically unstable patients and is associated with minimal complications. Embolization should be considered as an integral part of resuscitative measures for bleeding related to trauma.
Pulse-Spray Pharmacomechanical Thrombolysis of Native Arteriovenous Fistulas and Grafts under Ultrasound Guidance: Our Initial Experience
Authors: Vasanthraj Praveen , Bandi Varun , Sai Venkata , Shekar Manikanthan
Published: July 2017

Chronic renal diseases have been on rise with most patients requiring renal transplantation. With advances in treatment, patients undergo hemodialysis through arteriovenous (AV) fistulas and grafts. Thrombosis in these fistulas and grafts are more common and may result in failure. Interventional radiology plays an important role in managing these thromboses through catheter-directed thrombolysis. With success rate of more than 80%, catheter-directed thrombolysis has become the treatment of choice. However, the need of trained personnel, well-equipped catheter laboratories, and expensiveness are its disadvantages. We share our initial experience in two patients in whom we have performed ultrasound-guided percutaneous pulse-spray pharmacomechanical thrombolysis as a day-care procedure. This technique is less expensive, can have a wider outreach, and patients can be benefitted early to avoid new access.
Lenticulostriate Artery Aneurysm Associated with Cerebral Arteriovenous Malformation: Report of Rare Association and Its Endovascular Management
Authors: Kannath Santhosh , Rajan Jayadevan
Published: July 2017

Aneurysms involving the lenticulostriate arteries are rare and are described in the literature in small case series or single-case reports. In this report, we discuss a case of a young woman who presented with acute lateral ventricular bleed and was found to have an arteriovenous malformation within the corona radiata and an aneurysm involving the distal lenticulostriate artery. The aneurysm was treated successfully by endovascular embolization. In deep-seated arteriovenous malformations (AVMs) that are conventionally treated by stereotactic radiosurgery, a targeted approach for treatment of an associated aneurysm could be considered to reduce the risk of rebleed until the AVM is obliterated.
Radiation Safety Culture: The Way Forward in Practicing Interventional Radiology
Authors: Livingstone Roshan , Varghese Anna
Published: July 2017

Radiation dose from catheter-based interventional procedures performed in catheterization laboratories are of concern as an increase of radiation dose beyond threshold limits will be detrimental to the patient. It is important that radiation personnel understand the biological effects of radiation since patient and staff exposure may be significantly high when not adhered to radiation safety standards. Use of protective accessories, such as lead aprons and goggles, has been practiced worldwide for individual protection. Dose audit during interventional procedures is important for the benefit of the patient. Several factors including angiographic equipment, preset protocols, and tube angulations that influence radiation dose to patient and operators and hence modification on radiation safety work practices in the catheterization lab is warranted. Implementing periodic radiation safety training for occupational workers would be beneficial to practice a radiation safety culture.
Expanding Role of Endovascular Repair for Type B Aortic Dissection
Authors: Sharma Sanjiv , Sharma Arun
Published: July 2017

Aortic dissection is a medical emergency that can quickly lead to death, despite optimal treatment. The Stanford classification is widely used and is in close relationship to clinical practice, as type A dissections require primary surgical repair whereas type B dissections are treated medically as initial treatment with surgery or endovascular repair (EVR) reserved for any complications. Multislice CT is the investigation of choice to establish the diagnosis and plan treatment strategies. Therapeutic strategies differ for treatment of an acute dissection compared with a chronic dissection. Traditionally, most institutions favor a “complication specific” approach for type B dissection with antihypertensive treatment and use of β-blockers as primary therapy. Surgery or EVR is reserved for patients with recurrent pain, life-threatening complications, or rapid aortic expansion. With above algorithms, there is evidence that 30 to 50% patients on conservative therapy develop serious morbidity or mortality over 5-year period. Clinical and imaging markers of adverse outcome are being identified to revise the management strategies and offer EVR to those at risk for adverse outcome. This is especially relevant in view of the fact that EVR for type B dissection is associated with procedural success in 99.2 ± 0.1% patients. Overall survival rates of 96.9% at 30 days, 96.7% at 6 months, 96.4% at 1 year, 95.6% at 2 years, and 95.2% at 5 years are reported after EVR in type B dissections. There is emerging evidence that EVR may be noninferior to surgery in this group of patients. These observations along with the development of dissection-specific device designs have the potential to rewrite the management algorithms for type B aortic dissection and define the role of EVR in this disease.
Reversible Rapid Neck Swelling Following Carotid Artery Stenting: A Case Report
Authors: Keshava Shyamkumar , Mammen Thomas , Stephen Edwin , Agarwal Sunil
Published: July 2017

We report a case of rapid neck swelling from diffuse enlargement of the parotid gland that developed following stenting of the common carotid artery for significant stenosis in a postradiation scenario. Hyperperfusion was considered as the possible mechanism. The pathology and differential diagnoses are discussed. It was conservatively managed and there was significant reduction in the swelling within three days.
Do Patients Access Appropriate Information Online?
Authors: Gupta Amar , Bojrab Dennis , Folbe Adam , Carron Michael , Nissan Michael
Published: July 2017

Health care providers should be aware of information available on the Internet to ensure proper patient care. The current analysis assesses the reliability, quality, and readability of internet information describing rhytidectomy. Previously validated survey instruments to assess the reliability, quality, and readability of online websites describing rhytidectomy were used. An internet search using Google with the search term “facelift” was conducted. The first 50 search results were reviewed, and 36 were deemed appropriate to be included in this analysis. Websites were divided based on type of authorship into professional organization, academic, physician based, and unidentified. The validated DISCERN instrument was used to determine reliability, quality, and overall rating of each site. The Flesch Reading Ease Score (FRES) and Flesch–Kincaid Grade Level (FKGL) were used to measure readability. A 1 to 3 point scale was used to rate websites, with a higher number indicating a website that possessed either greater reliability or greater quality. Mean scores for reliability ranged from 1.7 (±0.99) in the academic group to 2.0 (±0.12) in the unidentified group. Mean scores for quality ranged from 1.5 (±0.13) in the unidentified group to 1.7 (±0.38) in the physician-based group. The highest overall rating was 1.4 (±0.22 and ± 0.31, respectively) in the unidentified and physician-based groups. The lowest overall rating was 1 (±0.58) in the academic group. FRESs ranged from 21.6 to 74.6. FKGLs ranged from 6.9 to 13.9. Information available online regarding rhytidectomy may be significantly deficient in reliability, quality, and readability. These deficiencies are present in articles with all types of author affiliations. This underscores the clinicians' duty to provide patients with high-quality information at an adequate level of comprehension.
Surgical Management of Degenerative Meniscus Lesions: The 2016 ESSKA Meniscus Consensus
Authors: Beaufils P. , Becker R. , Kopf S. , Englund M. , Verdonk R. , Ollivier M. , Seil R.
Published: July 2017

Purpose A degenerative meniscus lesion is a slowly developing process typically involving a horizontal cleavage in a middle-aged or older person. When the knee is symptomatic, arthroscopic partial meniscectomy has been practised for a long time with many case series reporting improved patient outcomes. Since 2002, several randomised clinical trials demonstrated no additional benefit of arthroscopic partial meniscectomy compared to non-operative treatment, sham surgery or sham arthroscopic partial meniscectomy. These results introduced controversy in the medical community and made clinical decision-making challenging in the daily clinical practice. To facilitate the clinical decision-making process, a consensus was developed. This initiative was endorsed by ESSKA.

Methods A degenerative meniscus lesion was defined as a lesion occurring without any history of significant acute trauma in a patient older than 35 years. Congenital lesions, traumatic meniscus tears and degenerative lesions occurring in young patients, especially in athletes, were excluded. The project followed the so-called formal consensus process, involving a steering group, a rating group and a peer-review group. A total of 84 surgeons and scientists from 22 European countries were included in the process. Twenty questions, their associated answers and an algorithm based on extensive literature review and clinical expertise, were proposed. Each question and answer set was graded according to the scientific level of the corresponding literature.

Results The main finding was that arthroscopic partial meniscectomy should not be proposed as a first line of treatment for degenerative meniscus lesions. Arthroscopic partial meniscectomy should only be considered after a proper standardised clinical and radiological evaluation and when the response to non-operative management has not been satisfactory. Magnetic resonance imaging of the knee is typically not indicated in the first-line work-up, but knee radiography should be used as an imaging tool to support a diagnosis of osteoarthritis or to detect certain rare pathologies, such as tumours or fractures of the knee.

Discussion The present work offers a clear framework for the management of degenerative meniscus lesions, with the aim to balance information extracted from the scientific evidence and clinical expertise. Because of biases and weaknesses of the current literature and lack of definition of important criteria such as mechanical symptoms, it cannot be considered as an exact treatment algorithm. It summarises the results of the “ESSKA Meniscus Consensus Project” (http://www.esska.org/education/projects) and is the first official European consensus on this topic. The consensus may be updated and refined as more high-quality evidence emerges.

Level of Evidence I.
Monitoring Outcome of Joint Arthroplasty in Italy: Implementation of the National Registry
Authors: Torre Marina , Romanini Emilio , Zanoli Gustavo , Carrani Eugenio , Luzi Ilaria , Leone Luisa , Bellino Stefania
Published: July 2017

Purpose Arthroplasty registries have an important role in improving outcomes in joint surgery. As the demand for joint arthroplasty continues to increase, growing attention is being paid to the establishment of national registries, which contribute to the enhancement of the quality of patients' care. Indeed, providing postmarketing surveillance data in terms of safety and effectiveness of medical devices, registries contribute to the best orthopaedic practice and support public health decision making. In this context, a project aimed at implementing a national arthroplasty registry in Italy has appeared to be essential, and the activities performed in the last years have consolidated data collection of hip and knee replacements.

Methods Based on a close cooperation among public health institutions, clinicians, and involved stakeholders, the architecture of the registry is built on three pillars: (1) data collected using Hospital Discharge Records (HDRs) integrated by an additional dataset, (2) implants identified and characterized in a dedicated medical devices library, and (3) a federation of regional registries coordinated by a public health institution, the Italian National Institute of Health.

Results Besides the organizational structure, statistical analyses on joint arthroplasty from national HDR database (2001–2014) and Italian registry data (2014) are presented. Currently, the institutions participating in the registry on a voluntary basis show 80% of completeness for hip and 58% for knee, and represent approximately 18% of the national volume.

Conclusion To make data collection effective, participation should be mandatory and ruled by a national law.

Level of Study Level III, observational analytic study.