bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Supplement from Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Sahin Aysegul , Tarco Emily , Carkaci Selin , Adrada Beatriz E. , Singh Gopal , Do Kim-Anh , Garces Zerzhinski M. , Mittendorf Elizabeth , Babiera Gildy , Bedrosian Isabelle , Hwang Rosa , Krishnamurthy Savitri , Symmans William F. , Gonzalez-Angulo Ana Maria , Mills Gordon B.
Published: April 2023

Supplementary Table 3. Response to REMARK guidelines
Supplementary Table 2 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Authors: Koochekpour Shahriar , Majumdar Sunipa , Azabdaftari Gissou , Attwood Kristopher , Scioneaux Ray , Subramani Dhatchayini , Manhardt Charles , Lorusso Giovanni D. , Willard Stacey S. , Thompson Hillary , Shourideh Mojgan , Rezaei Katayoon , Sartor Oliver , Mohler James L. , Vessella Robert L.
Published: April 2023

PDF file - 75K, Multiple covariate adjusted analysis of serum glutamate levels in patients with primary and metastatic castrate-resistant prostate cancer
Data Supplement from Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Sahin Aysegul , Tarco Emily , Carkaci Selin , Adrada Beatriz E. , Singh Gopal , Do Kim-Anh , Garces Zerzhinski M. , Mittendorf Elizabeth , Babiera Gildy , Bedrosian Isabelle , Hwang Rosa , Krishnamurthy Savitri , Symmans William F. , Gonzalez-Angulo Ana Maria , Mills Gordon B.
Published: April 2023

Supplementary Table 4. Patient and tumor characteristics
Supplementary Figure 2 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Authors: Koochekpour Shahriar , Majumdar Sunipa , Azabdaftari Gissou , Attwood Kristopher , Scioneaux Ray , Subramani Dhatchayini , Manhardt Charles , Lorusso Giovanni D. , Willard Stacey S. , Thompson Hillary , Shourideh Mojgan , Rezaei Katayoon , Sartor Oliver , Mohler James L. , Vessella Robert L.
Published: April 2023

PDF file - 61K, Immunohistochemical staining of metabotropic glutamate receptor 1 (GRM1) in selected non-malignant prostatic tissues
Supplementary Tables 1 - 3 from Predictors of Survival in Never-Smokers with Non–Small Cell Lung Cancer: A Large-Scale, Two-Phase Genetic Study
Authors: Pu Xia , Ye Yuanqing , Spitz Margaret R. , Wang Liang , Gu Jian , Lippman Scott M. , Hildebrandt Michelle A.T. , Hong Waun Ki , Minna John D. , Roth Jack A. , Yang Ping , Wu Xifeng
Published: April 2023

PDF file - 83k, Supplementary Table 1: Inflammation-related pathways selected in this study Supplementary Table 2: Effect of selected SNPs on survival in adenocarcinoma female patients Supplementary Table 3: Effect of selected SNPs on survival duration in patients with late-stage lung cancer Supplementary Table 4: Effect of selected SNPs on survival duration in patients by gender
Supplementary Figure 2 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 832K, Example Digital PCR analysis in 384 well plate.
Supplementary Figure 1 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 1282, Digital PCR assay for HER2 on 384 well microplates.
Supplementary Table 4 from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

PDF file - 46K, Univariate and Multivariate Analysis for pCR.
Supplementary Figures 1 - 3 from The Critical Role of Dysregulated FOXM1–PLAUR Signaling in Human Colon Cancer Progression and Metastasis
Authors: Li Dawei , Wei Ping , Peng Zhihai , Huang Chen , Tang Huamei , Jia Zhiliang , Cui Jiujie , Le Xiangdong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 502K, S1. FOXM1 and PLAUR expression in colon cancer specimens; S2. The effect of FOXM1 expression on colon cancer cell migration and invasion; S3. Transcriptional activation of PLAUR expression in colon cancer cells by FOXM1
Supplementary Table 1 from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

XLSX file - 16K, List of mouse C3(1)-T-antigen gene expression microarrays used to derive the murine gene lists.
Supplementary Figure 3 from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

PDF file - 1539K, Kaplan-Meier analyses for the prediction of Distant Relapse Free Survival.
Supplementary Figure 1 from Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein Phosphorylation in AML Blasts during a Clinical Trial Combining the mTOR Inhibitor Sirolimus and Intensive Chemotherapy
Authors: Perl Alexander E. , Kasner Margaret T. , Shank Doris , Luger Selina M. , Carroll Martin
Published: April 2023

PDF file - 583K, Basal phosphorylation of S6 is heterogeneous in leukemic sub-populations.
Supplementary Figure 2 from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

PDF file - 3255K, Hierarchical clustering analysis of the untreated and responding murine chemotherapy signature using 337 human breast tumors.
Data Supplement from CSPG4-Specific Immunity and Survival Prolongation in Dogs with Oral Malignant Melanoma Immunized with Human CSPG4 DNA
Authors: Riccardo Federica , Iussich Selina , Maniscalco Lorella , Lorda Mayayo Saray , La Rosa Giuseppe , Arigoni Maddalena , De Maria Raffaella , Gattino Francesca , Lanzardo Stefania , Lardone Elena , Martano Marina , Morello Emanuela , Prestigio Simone , Fiore Alessandra , Quaglino Elena , Zabarino Sara , Ferrone Soldano , Buracco Paolo , Cavallo Federica
Published: April 2023

Supplementary Table S1. Breed, sex and age of canine patient population Supplementary Table S2. Age and body weight characteristics of canine patient population
Supplementary Table 2 from Novel Tumor Subgroups of Urothelial Carcinoma of the Bladder Defined by Integrated Genomic Analysis
Authors: Hurst Carolyn D. , Platt Fiona M. , Taylor Claire F. , Knowles Margaret A.
Published: April 2023

PDF file, 44K, TP53 and FGFR3 mutation in all Ta tumors, and tumors from individual T1G3 and ≥T2 clusters.
Supplementary Table 3 from [18F]-3′Deoxy-3′-Fluorothymidine Positron Emission Tomography and Breast Cancer Response to Docetaxel
Authors: Contractor Kaiyumars B. , Kenny Laura M. , Stebbing Justin , Rosso Lula , Ahmad Rizvana , Jacob Jimmy , Challapalli Amarnath , Turkheimer Federico , Al-Nahhas Adil , Sharma Rohini , Coombes R. Charles , Aboagye Eric O.
Published: April 2023

PDF file - 46K, Changes in FLT SUV after 1 and 2 cycles of docetaxel.
Supplementary Table 2 from [18F]-3′Deoxy-3′-Fluorothymidine Positron Emission Tomography and Breast Cancer Response to Docetaxel
Authors: Contractor Kaiyumars B. , Kenny Laura M. , Stebbing Justin , Rosso Lula , Ahmad Rizvana , Jacob Jimmy , Challapalli Amarnath , Turkheimer Federico , Al-Nahhas Adil , Sharma Rohini , Coombes R. Charles , Aboagye Eric O.
Published: April 2023

PDF file - 45K, SUV in tumors normalized to body weight.
Supplementary Table 1 from Novel Tumor Subgroups of Urothelial Carcinoma of the Bladder Defined by Integrated Genomic Analysis
Authors: Hurst Carolyn D. , Platt Fiona M. , Taylor Claire F. , Knowles Margaret A.
Published: April 2023

PDF file, 86K, Clinico-pathological characteristics, mutation status and FGA in 160 UC.
Supplementary Figure 6 from Novel Tumor Subgroups of Urothelial Carcinoma of the Bladder Defined by Integrated Genomic Analysis
Authors: Hurst Carolyn D. , Platt Fiona M. , Taylor Claire F. , Knowles Margaret A.
Published: April 2023

PDF file, 902K, Loss and gain in tumors from individual Ta, T1 and ≥T2 clusters.
Supplementary Figures 1 - 3 and Table 1 from BRCA2 Deep Intronic Mutation Causing Activation of a Cryptic Exon: Opening toward a New Preventive Therapeutic Strategy
Authors: Anczuków Olga , Buisson Monique , Léoné Mélanie , Coutanson Christine , Lasset Christine , Calender Alain , Sinilnikova Olga M. , Mazoyer Sylvie
Published: April 2023

PDF file, 764K, BRCA2 exon 12 to exon 13 gene, transcript and protein sequences (Supp Fig 1); Enhancer motifs contained within the cryptic exon and the constitutive surrounding exons (Supp Fig 2); Conservation of the cryptic exon across species (Supp Fig 3); Primers used for BRCA1 and BRCA2 routine mRNA analyses (Supp Table 1).
Supplementary Data from Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging
Authors: Nguyen Quang-Dé , Lavdas Ioannis , Gubbins James , Smith Graham , Fortt Robin , Carroll Laurence S. , Graham Martin A. , Aboagye Eric O.
Published: April 2023

PDF file - 1861K, Supplementary Figure S1. A, longitudinal 18FICMT-11 study, using 38C13 tumorbearing mice (n = 3) treated with 40 mg/kg CPA and imaged pre- and post-treatment as indicated. Supplementary Figure S2. Assessment of CPA-induced non-tumor modulation of radiotracer pharmacokinetics with 18FICMT-11 PET imaging. Supplementary Figure S3. Ex vivo assessment of CPA-induced liver apoptosis. Supplementary Figure S4. Assessment of the spatial distribution of 18FICMT-11 tumor uptake in relation with the intrinsic tumor heterogeneity. Supplementary Figure S5. A, Longitudinal 18FICMT-11 study, using HCT116 tumor-bearing mice (n = 5) treated with a single dose (15 mg/kg) of birinapant and evaluated pre- and post-treatment as indicated. Supplementary Figure S6. Assessment of birinapant proof of mechanism (cIAP-1 protein downregulation) and proof of concept (induction of tumor apoptosis). Supplementary Figure S7. Assessment of birinapant-induced non-tumor radiotracer modulation with 18FICMT-11 PET imaging. Supplementary Figure S8. A, Longitudinal 18FICMT-11 study, using MDA-MB-231 tumor-bearing mice (n = 5) treated with a 15 mg/kg single dose birinapant and imaged pre- and post-treatment as indicated. Supplementary Figure S9. Assessment of tumor apoptosis induction by immunohistochemistry detection of tumor active caspase-3 and TUNEL at 6h following treatment of MDA-MB-231 tumor bearing mice with a single dose of birinapant (15 mg/kg) or corresponding vehicle
Supplementary Tables from Long-term Survival and Biomarker Correlates of Tasquinimod Efficacy in a Multicenter Randomized Study of Men with Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer
Authors: Armstrong A.J. , Häggman M. , Stadler W.M. , Gingrich J.R. , Assikis V. , Polikoff J. , Damber J.E. , Belkoff L. , Nordle Ö. , Forsberg G. , Carducci M.A. , Pili R.
Published: April 2023

PDF file 67K, Supplementary Table 1. Baseline characteristics of patients in the trial and subgroups investigated, including parameters used in the multivariate analysis. The following abbreviations are used: ITT=Intention to treat, VAS=visual analog scale (linear pain rating of 0-10), PSA=prostate specific antigen, PSADT=PSA doubling time, PCWG2= PC Working Group 2 Guidelines, SD=standard deviation. Supplementary table 2. Characteristics at baseline and at the end of open-label treatment for patients treated in the placebo group during the double blind phase of the trial, grouped according to whether the subject received open label tasquinimod or not
Supplementary Legend from Biomarker Modulation following Short-Term Vorinostat in Women with Newly Diagnosed Primary Breast Cancer
Authors: Stearns Vered , Jacobs Lisa K. , Fackler MaryJo , Tsangaris Theodore N. , Rudek Michelle A. , Higgins Michaela , Lange Julie , Cheng Zandra , Slater Shannon A. , Jeter Stacie C. , Powers Penny , Briest Susanne , Chao Calvin , Yoshizawa Carl , Sugar Elizabeth , Espinoza-Delgado Igor , Sukumar Saraswati , Gabrielson Edward , Davidson Nancy E.
Published: April 2023

PDF file, 67K
Supplementary Tables S1-S6 from Epigenetic Inactivation of microRNA-34b/c Predicts Poor Disease-Free Survival in Early-Stage Lung Adenocarcinoma
Authors: Nadal Ernest , Chen Guoan , Gallegos Marc , Lin Lin , Ferrer-Torres Daysha , Truini Anna , Wang Zhuwen , Lin Jules , Reddy Rishindra M. , Llatjos Roger , Escobar Ignacio , Moya Juan , Chang Andrew C. , Cardenal Felipe , Capellà Gabriel , Beer David G.
Published: April 2023

PDF file115K, Suppl.Table S1. Patient characteristics. Suppl.Table S2. Lung AC lines with TP53 mutation. Suppl.Table S3. Primers used for qRT-PCR. Suppl.Table S4. Correlation between tumors miR-34b/c expression and clinical and molecular variables. Suppl.Table S5. Multivariate Cox model for DFS based upon miR-34b/c methylation (continuous). Suppl.Table S6. Multivariate Cox model for OS in 140 patients
Supplementary Figure 2 from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma
Authors: Lee Sun Joo , Ghosh Sukhen C. , Han Hee Dong , Stone Rebecca L. , Bottsford-Miller Justin , Shen De Yue , Auzenne Edmond J. , Lopez-Araujo Alejandro , Lu Chunhua , Nishimura Masato , Pecot Chad V. , Zand Behrouz , Thanapprapasr Duangmani , Jennings Nicholas B , Kang Yu , Huang Jie , Hu Wei , Klostergaard Jim , Sood Anil K.
Published: April 2023

PDF file, 67KB, Effects of HA-TXL MTD and HA-TXL MET on white blood count (WBC)and hemoglobin levels.
Supplementary Figure S8 from Epigenetic Inactivation of microRNA-34b/c Predicts Poor Disease-Free Survival in Early-Stage Lung Adenocarcinoma
Authors: Nadal Ernest , Chen Guoan , Gallegos Marc , Lin Lin , Ferrer-Torres Daysha , Truini Anna , Wang Zhuwen , Lin Jules , Reddy Rishindra M. , Llatjos Roger , Escobar Ignacio , Moya Juan , Chang Andrew C. , Cardenal Felipe , Capellà Gabriel , Beer David G.
Published: April 2023

PDF file 263K, Representative examples of invasion assay in SK-LU-1 cells
Supplementary Figure 1 from Metronomic Activity of CD44-Targeted Hyaluronic Acid-Paclitaxel in Ovarian Carcinoma
Authors: Lee Sun Joo , Ghosh Sukhen C. , Han Hee Dong , Stone Rebecca L. , Bottsford-Miller Justin , Shen De Yue , Auzenne Edmond J. , Lopez-Araujo Alejandro , Lu Chunhua , Nishimura Masato , Pecot Chad V. , Zand Behrouz , Thanapprapasr Duangmani , Jennings Nicholas B , Kang Yu , Huang Jie , Hu Wei , Klostergaard Jim , Sood Anil K.
Published: April 2023

PDF file, 104KB, Effects of MET and MTD HA-TXL therapy on tumor nodules in ovarian cancer models.
Supplementary Figure S5 from Epigenetic Inactivation of microRNA-34b/c Predicts Poor Disease-Free Survival in Early-Stage Lung Adenocarcinoma
Authors: Nadal Ernest , Chen Guoan , Gallegos Marc , Lin Lin , Ferrer-Torres Daysha , Truini Anna , Wang Zhuwen , Lin Jules , Reddy Rishindra M. , Llatjos Roger , Escobar Ignacio , Moya Juan , Chang Andrew C. , Cardenal Felipe , Capellà Gabriel , Beer David G.
Published: April 2023

PDF file 74K, Kaplan-Meier plot of DFS according to miR-34b/c methylation level in 97 stage I lung AC patients
Supplementary Figure S4 from Epigenetic Inactivation of microRNA-34b/c Predicts Poor Disease-Free Survival in Early-Stage Lung Adenocarcinoma
Authors: Nadal Ernest , Chen Guoan , Gallegos Marc , Lin Lin , Ferrer-Torres Daysha , Truini Anna , Wang Zhuwen , Lin Jules , Reddy Rishindra M. , Llatjos Roger , Escobar Ignacio , Moya Juan , Chang Andrew C. , Cardenal Felipe , Capellà Gabriel , Beer David G.
Published: April 2023

PDF file 88K, Kaplan-Meier plots of DFS and OS according to miR-34b/c methylation in 140 early stage lung AC patients
Supplementary Figure 2 from Impact of Expression of Human Epidermal Growth Factor Receptors EGFR and ERBB2 on Survival in Stage II/III Gastric Cancer
Authors: Terashima Masanori , Kitada Koji , Ochiai Atsushi , Ichikawa Wataru , Kurahashi Issei , Sakuramoto Shinichi , Katai Hitoshi , Sano Takeshi , Imamura Hiroshi , Sasako Mitsuru
Published: April 2023

PDF file - 359K, Representative examples of gastric carcinoma immunostaining for HER2 (magnification � 100)
Supplementary Acknowledgements from Impact of Expression of Human Epidermal Growth Factor Receptors EGFR and ERBB2 on Survival in Stage II/III Gastric Cancer
Authors: Terashima Masanori , Kitada Koji , Ochiai Atsushi , Ichikawa Wataru , Kurahashi Issei , Sakuramoto Shinichi , Katai Hitoshi , Sano Takeshi , Imamura Hiroshi , Sasako Mitsuru
Published: April 2023

PDF file - 87K
Supplementary Figure 3 from Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays
Authors: Manfredi Mark G. , Ecsedy Jeffrey A. , Chakravarty Arijit , Silverman Lee , Zhang Mengkun , Hoar Kara M. , Stroud Stephen G. , Chen Wei , Shinde Vaishali , Huck Jessica J. , Wysong Deborah R. , Janowick David A. , Hyer Marc L. , LeRoy Patrick J. , Gershman Rachel E. , Silva Matthew D. , Germanos Melissa S. , Bolen Joseph B. , Claiborne Christopher F. , Sells Todd B.
Published: April 2023

PDF file - 65K
Supplementary Figure 2 from Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays
Authors: Manfredi Mark G. , Ecsedy Jeffrey A. , Chakravarty Arijit , Silverman Lee , Zhang Mengkun , Hoar Kara M. , Stroud Stephen G. , Chen Wei , Shinde Vaishali , Huck Jessica J. , Wysong Deborah R. , Janowick David A. , Hyer Marc L. , LeRoy Patrick J. , Gershman Rachel E. , Silva Matthew D. , Germanos Melissa S. , Bolen Joseph B. , Claiborne Christopher F. , Sells Todd B.
Published: April 2023

PDF file - 36K
Supplementary Figure 1 from Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays
Authors: Manfredi Mark G. , Ecsedy Jeffrey A. , Chakravarty Arijit , Silverman Lee , Zhang Mengkun , Hoar Kara M. , Stroud Stephen G. , Chen Wei , Shinde Vaishali , Huck Jessica J. , Wysong Deborah R. , Janowick David A. , Hyer Marc L. , LeRoy Patrick J. , Gershman Rachel E. , Silva Matthew D. , Germanos Melissa S. , Bolen Joseph B. , Claiborne Christopher F. , Sells Todd B.
Published: April 2023

PDF file - 27K
Supplementary Table 3 from Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response
Authors: Wong Harvey , Choo Edna F. , Alicke Bruno , Ding Xiao , La Hank , McNamara Erin , Theil Frank-Peter , Tibbitts Jay , Friedman Lori S. , Hop Cornelis E.C.A. , Gould Stephen E.
Published: April 2023

PDF file, 91KB, Population Pharmacodynamic Parameter Estimates for Anti-Cancer Agents.
Supplementary Table 1 from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
Authors: Spreafico Anna , Tentler John J. , Pitts Todd M. , Tan Aik Choon , Gregory Mark A. , Arcaroli John J. , Klauck Peter J. , McManus Martine C. , Hansen Ryan J. , Kim Jihye , Micel Lindsey N. , Selby Heather M. , Newton Timothy P. , McPhillips Kelly L. , Gustafson Daniel L. , DeGregori James V. , Messersmith Wells A. , Winn Robert A. , Eckhardt S. Gail
Published: April 2023

Supplementary Table 1 - PDF file 70K, Supplementary Table 1 Top 20 pathways enriched in selumetinib resistant CRC cell lines
Supplementary Figures 1-6 from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
Authors: Spreafico Anna , Tentler John J. , Pitts Todd M. , Tan Aik Choon , Gregory Mark A. , Arcaroli John J. , Klauck Peter J. , McManus Martine C. , Hansen Ryan J. , Kim Jihye , Micel Lindsey N. , Selby Heather M. , Newton Timothy P. , McPhillips Kelly L. , Gustafson Daniel L. , DeGregori James V. , Messersmith Wells A. , Winn Robert A. , Eckhardt S. Gail
Published: April 2023

Supplementary Figures 1-6 - PDF file 458K, Power point files of Figures 1-6. For details see legends file
Supplementary Figure 2 from Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response
Authors: Wong Harvey , Choo Edna F. , Alicke Bruno , Ding Xiao , La Hank , McNamara Erin , Theil Frank-Peter , Tibbitts Jay , Friedman Lori S. , Hop Cornelis E.C.A. , Gould Stephen E.
Published: April 2023

PDF file, 43KB, Representative plots of mean tumor volume versus time are shown for A549, H520, Calu-6 and H460 xenografts given daily oral doses of erlotinib at 50 mg/kg.
Supplementary Figure 1 from Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response
Authors: Wong Harvey , Choo Edna F. , Alicke Bruno , Ding Xiao , La Hank , McNamara Erin , Theil Frank-Peter , Tibbitts Jay , Friedman Lori S. , Hop Cornelis E.C.A. , Gould Stephen E.
Published: April 2023

PDF file, 58KB, Representative plots of mean tumor volume versus time are shown for dose ranging studies with various anti-cancer agents in xenograft/allograft mice.
Supplementary Figures 1 - 3, Tables 1 - 3 from Molecular Epidemiology of EGFR and KRAS Mutations in 3,026 Lung Adenocarcinomas: Higher Susceptibility of Women to Smoking-Related KRAS-Mutant Cancers
Authors: Dogan Snjezana , Shen Ronglai , Ang Daphne C. , Johnson Melissa L. , D'Angelo Sandra P. , Paik Paul K. , Brzostowski Edyta B. , Riely Gregory J. , Kris Mark G. , Zakowski Maureen F. , Ladanyi Marc
Published: April 2023

PDF file - 225K, Supplementary Figure 1. (A) Gender differences in frequency of EGFR mutations by stage. Men with EGFR mutations presented at the late stage more often than women (118/170, 69% vs. 235/423, 56%; p=0.002); women predominated at stage I (31% vs. 19%, p=0.004). (B) Stage distribution of EGFR exon 19 del and EGFR L858R. EGFR L858R were significantly more frequent at stage I than exon 19 del (83/246, 34% vs. 82/347, 24%; p=0.009); Fisher exact test, P value <0.01 is considered significant. Supplementary Figure 2: (A) Age and (B) stage distribution of KRAS mutations (4 major subtypes) Supplementary Figure 3: EGFR mutation nomogram ROC curve in the validation cohort. Supplementary Table 1. (A) The association of the smoking-free years and pack-years of smoking with EGFR mutational status. Smoking-free years impact on likelihood of EGFR mutation. (Multivariate logistic regression analysis). (B) The association of the smoking-free years and pack-years of smoking with KRAS mutational status. Smoking-free years do not impact on likelihood of KRAS mutation. (Multivariate logistic regression analysis). Supplementary Table 2. Age and gender differences in pack-years of smoking in relation to KRAS mutation nucleotide change. Women with G>T transversions had smoked less (average 34 pack-years vs. 40 pack-years, p=0.001) and were younger than men with the same nucleotide change (median age 64 vs. 67, p=0.006). Fisher exact test, P value <0.01 is considered significant.
Supplementary Figure 1 from Defective Epidermal Innate Immunity and Resultant Superficial Dermatophytosis in Adult T-cell Leukemia/Lymphoma
Authors: Sawada Yu , Nakamura Motonobu , Kabashima-Kubo Rieko , Shimauchi Takatoshi , Kobayashi Miwa , Tokura Yoshiki
Published: April 2023

PDF file, 528KB, Flow cytometric analysis of IL-17+ cells in peripheral blood lymphocytes. PBMCs isolated from healthy controls, dermatophytosis patients without ATLL, ATLL without dermatophytosis patients.
Supplementary Table 5 from HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
Authors: Li Ling , Tang Wenhua , Wu Xiaoqing , Karnak David , Meng Xiaojie , Thompson Rachel , Hao Xinbao , Li Yongmin , Qiao Xiaotan T. , Lin Jiayuh , Fuchs James , Simeone Diane M. , Chen Zhi-Nan , Lawrence Theodore S. , Xu Liang
Published: April 2023

PDF file - 61K, The efficiency of HAb18G/CD147 knock-down using pGIPZ and pTRIPZ shRNA vector in human pancreatic cancer cells (related to Figure 1).
Supplementary Figure 4 from HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
Authors: Li Ling , Tang Wenhua , Wu Xiaoqing , Karnak David , Meng Xiaojie , Thompson Rachel , Hao Xinbao , Li Yongmin , Qiao Xiaotan T. , Lin Jiayuh , Fuchs James , Simeone Diane M. , Chen Zhi-Nan , Lawrence Theodore S. , Xu Liang
Published: April 2023

PDF file - 263K, The effects of HAb18G/CD147 promoting pancreatic tumor development are confirmed with pGIPZ and pTRIPZ CD147 shRNA (related to Figure 1).
Supplementary Figure 2 from HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
Authors: Li Ling , Tang Wenhua , Wu Xiaoqing , Karnak David , Meng Xiaojie , Thompson Rachel , Hao Xinbao , Li Yongmin , Qiao Xiaotan T. , Lin Jiayuh , Fuchs James , Simeone Diane M. , Chen Zhi-Nan , Lawrence Theodore S. , Xu Liang
Published: April 2023

PDF file - 397K, HAb18G/CD147, pSTAT3 and survivin levels in a panel of human pancreatic cancer cell lines (related to Figure 1, 2A).
Supplementary Methods, Schemes 1 - 2, Figures 1 - 2, Tables 1 - 2 from Targeted Delivery of Paclitaxel to EphA2-Expressing Cancer Cells
Authors: Wang Si , Noberini Roberta , Stebbins John L. , Das Swadesh , Zhang Ziming , Wu Bainan , Mitra Sayantan , Billet Sandrine , Fernandez Ana , Bhowmick Neil A. , Kitada Shinichi , Pasquale Elena B. , Fisher Paul B. , Pellecchia Maurizio
Published: April 2023

PDF file - 328K, Scheme 1. Synthesis of YNH motif and dYNH motif Scheme S2. Synthetic route for YSA-PTX Figure S1. In vivo prostate cancer xenograft studies. Figure S2. EphA2 expression in RENCA renal carcinoma cells and PC3M prostate cancer cells. Supplemental Table 1. Athymic nude mice bearing pre-established subcutaneous PC3M tumors (230 mm3 average volume) were treated three times weekly for a period of 18 days (8 total injections) with intravenous doses of vehicle (CT), PTX (10 mg/Kg) and DYP-PTX or YSA-PTX (at a dose equimolar to the taxol dose).
Supplementary Table 1 from Regulatory Polymorphisms in β-Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy
Authors: Leandro-García Luis J. , Leskelä Susanna , Jara Carlos , Gréen Henrik , Åvall-Lundqvist Elisabeth , Wheeler Heather E. , Dolan M. Eileen , Inglada-Perez Lucia , Maliszewska Agnieszka , de Cubas Aguirre A. , Comino-Méndez Iñaki , Mancikova Veronika , Cascón Alberto , Robledo Mercedes , Rodríguez-Antona Cristina
Published: April 2023

PDF file, 52KB, Oligonucleotides used for β-tubulins mRNA quantification and TUBB2A sequencing and cloning.
Supplementary Figure 2 from Regulatory Polymorphisms in β-Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy
Authors: Leandro-García Luis J. , Leskelä Susanna , Jara Carlos , Gréen Henrik , Åvall-Lundqvist Elisabeth , Wheeler Heather E. , Dolan M. Eileen , Inglada-Perez Lucia , Maliszewska Agnieszka , de Cubas Aguirre A. , Comino-Méndez Iñaki , Mancikova Veronika , Cascón Alberto , Robledo Mercedes , Rodríguez-Antona Cristina
Published: April 2023

PDF file, 45KB, Putative binding sites for transcription factors in TUBB2A proximal promoter.
Supplementary Figure 5 from EGFR Protein Expression in Non–Small Cell Lung Cancer Predicts Response to an EGFR Tyrosine Kinase Inhibitor—A Novel Antibody for Immunohistochemistry or AQUA Technology
Authors: Mascaux Celine , Wynes Murry W. , Kato Yasufumi , Tran Cindy , Asuncion Bernadette Reyna , Zhao Jason M. , Gustavson Mark , Ranger-Moore Jim , Gaire Fabien , Matsubayashi Jun , Nagao Toshitaka , Yoshida Koichi , Ohira Tatuso , Ikeda Norihiko , Hirsch Fred R.
Published: April 2023

PDF file - 122KB
Supplementary Tables A-B, Figures A-D from Prognostic and Predictive Significance of Plasma HGF and IL-8 in a Phase III Trial of Chemoradiation with or without Tirapazamine in Locoregionally Advanced Head and Neck Cancer
Authors: Le Quynh-Thu , Fisher Richard , Oliner Kelly S. , Young Richard J. , Cao Hongbin , Kong Christina , Graves Edward , Hicks Rodney J. , McArthur Grant A. , Peters Lester , O'Sullivan Brian , Giaccia Amato , Rischin Danny
Published: April 2023

PDF file - 105K
Supplementary Figure 1 from EGFR Protein Expression in Non–Small Cell Lung Cancer Predicts Response to an EGFR Tyrosine Kinase Inhibitor—A Novel Antibody for Immunohistochemistry or AQUA Technology
Authors: Mascaux Celine , Wynes Murry W. , Kato Yasufumi , Tran Cindy , Asuncion Bernadette Reyna , Zhao Jason M. , Gustavson Mark , Ranger-Moore Jim , Gaire Fabien , Matsubayashi Jun , Nagao Toshitaka , Yoshida Koichi , Ohira Tatuso , Ikeda Norihiko , Hirsch Fred R.
Published: April 2023

PDF file, 184KB
Supplementary Tables 1 - 3, Figure 1 from Vitamin E Protects against Lipid Peroxidation and Rescues Tumorigenic Phenotypes in Cowden/Cowden-like Patient-Derived Lymphoblast Cells with Germline SDHx Variants
Authors: Ni Ying , Eng Charis
Published: April 2023

PDF file, 205K, Table S1: International Cowden Syndrome Consortium Operational Criteria for the Diagnosis of Cowden Syndrome Table S2: Germline SDH variants detected in PTEN mutation negative or PTEN mutation positive CS/CSL individuals Table S3: Summary of total frequency of each mitochondrial DNA polymorphism observed in HVRII region in controls, SDHxvar+ positive, and PTENmut+/SDHxvar+ variant double positive CS/CSL individuals Figure S1: Western blot of whole cell lysates of controls and SDHx variant positive CS/CSL patient cells with DMSO, 100 uM vitamin E, or 800 uM vitamin E treatment.
Supplementary Table 2 from A Personalized Preclinical Model to Evaluate the Metastatic Potential of Patient-Derived Colon Cancer Initiating Cells
Authors: Puig Isabel , Chicote Irene , Tenbaum Stephan P. , Arqués Oriol , Herance José Raúl , Gispert Juan D. , Jimenez José , Landolfi Stefania , Caci Karina , Allende Helena , Mendizabal Leire , Moreno Debora , Charco Ramón , Espín Eloy , Prat Aleix , Elez Maria Elena , Argilés Guillem , Vivancos Ana , Tabernero Josep , Rojas Santiago , Palmer Héctor G.
Published: April 2023

PDF file - 290K, Histopathological and genetic traits of CRC PDX.
Supplementary Table 1 from A Personalized Preclinical Model to Evaluate the Metastatic Potential of Patient-Derived Colon Cancer Initiating Cells
Authors: Puig Isabel , Chicote Irene , Tenbaum Stephan P. , Arqués Oriol , Herance José Raúl , Gispert Juan D. , Jimenez José , Landolfi Stefania , Caci Karina , Allende Helena , Mendizabal Leire , Moreno Debora , Charco Ramón , Espín Eloy , Prat Aleix , Elez Maria Elena , Argilés Guillem , Vivancos Ana , Tabernero Josep , Rojas Santiago , Palmer Héctor G.
Published: April 2023

XLSX file - 768K, Nanostring CRC codeset.
Supplementary Figure 4 from Identification of Unique MEK-Dependent Genes in GNAQ Mutant Uveal Melanoma Involved in Cell Growth, Tumor Cell Invasion, and MEK Resistance
Authors: Ambrosini Grazia , Pratilas Christine A. , Qin Li-Xuan , Tadi Madhavi , Surriga Oliver , Carvajal Richard D. , Schwartz Gary K.
Published: April 2023

PDF file, 1823KB, DDX21 knockdown by siRNA inhibits cell proliferation of uveal melanoma.
Supplementary Figure 3 from A Personalized Preclinical Model to Evaluate the Metastatic Potential of Patient-Derived Colon Cancer Initiating Cells
Authors: Puig Isabel , Chicote Irene , Tenbaum Stephan P. , Arqués Oriol , Herance José Raúl , Gispert Juan D. , Jimenez José , Landolfi Stefania , Caci Karina , Allende Helena , Mendizabal Leire , Moreno Debora , Charco Ramón , Espín Eloy , Prat Aleix , Elez Maria Elena , Argilés Guillem , Vivancos Ana , Tabernero Josep , Rojas Santiago , Palmer Héctor G.
Published: April 2023

PDF file - 1113K, Patient-derived cells preserve pluripotency.
Supplementary Table 2 from Genomic Estimates of Aneuploid Content in Glioblastoma Multiforme and Improved Classification
Authors: Li Bo , Senbabaoglu Yasin , Peng Weiping , Yang Min-Lee , Xu Jishu , Li Jun Z.
Published: April 2023

XLS file, 203K, Selected molecular signatures distinguishing non-Proneural and PN/G-CIMP+ GBMs.
Supplementary Figure 5 from Effective Activity of Cytokine-Induced Killer Cells against Autologous Metastatic Melanoma Including Cells with Stemness Features
Authors: Gammaitoni Loretta , Giraudo Lidia , Leuci Valeria , Todorovic Maja , Mesiano Giulia , Picciotto Franco , Pisacane Alberto , Zaccagna Alessandro , Volpe Maria Giuseppa , Gallo Susanna , Caravelli Daniela , Giacone Elena , Venesio Tiziana , Balsamo Antonella , Pignochino Ymera , Grignani Giovanni , Carnevale-Schianca Fabrizio , Aglietta Massimo , Sangiolo Dario
Published: April 2023

PDF file - 81K, Representative flow cytometry analysis of melanoma primary transduced cells.
Supplementary Methods from Genomic Estimates of Aneuploid Content in Glioblastoma Multiforme and Improved Classification
Authors: Li Bo , Senbabaoglu Yasin , Peng Weiping , Yang Min-Lee , Xu Jishu , Li Jun Z.
Published: April 2023

PDF file, 323K.
Supplementary Figures 1-14 from Genomic Estimates of Aneuploid Content in Glioblastoma Multiforme and Improved Classification
Authors: Li Bo , Senbabaoglu Yasin , Peng Weiping , Yang Min-Lee , Xu Jishu , Li Jun Z.
Published: April 2023

PDF file, 6233K, S1: Inference of Aneuploid Genome Proportion and its goodness-of-fit measures; Figure S2: Histolopathological estimates of tumor purities versus AGP; S3: Relationship between AGP and gene expression pattern in ovarian cancer (OV); S4: PCA plots for CNA and CNA-MicroRNA joint analysis; S5: Principal component analyses of gene expression and CNA data for GBM2; S6: Clustering pattern of three data types: PC1 of copy number data, PC1 of expression data, and PC2 of methylation data; S7: Classification of Non-Proneural GBM tumors; S8: Cross-correlation analysis of GBM1-GBM2 at K=3 and 4; S9: Comparison between the revised and the previous GBM classification systems; S10: Cross-correlation analysis between GBM1 and Phillips' dataset at K=2, 3 and 4; S11: PCA plots for 46 Non-Proneural GBM samples in Phillips' dataset; S12: Survival time differences between GBM subtypes, compared between the current and previous classification systems; S13: Cox proportional hazard regression analysis with GBM subtypes as covariates, along with age and Karnofsky performance scores (KPS); S14: Four clusters formed by the 38 reference samples in the Cahoy's dataset.
Supplementary Figure 4 from Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts
Authors: Tate Sonya C. , Cai Shufen , Ajamie Rose T. , Burke Teresa , Beckmann Richard P. , Chan Edward M. , De Dios Alfonso , Wishart Graham N. , Gelbert Lawrence M. , Cronier Damien M.
Published: April 2023

PDF file - 247KB, Model simulations of the plasma concentration, the biomarker levels of p-Rb, TopoIIalpha and pHH3, and the effect parameters driving tumor growth inhibition for a 21 day daily dosing regimen of 25 (red line), 50 (blue line) and 100 mg/kg (green line) LY2835219 using the mean parameter estimates.
Supplementary Material 5 from The Antibody-Based Delivery of Interleukin-12 to the Tumor Neovasculature Eradicates Murine Models of Cancer in Combination with Paclitaxel
Authors: Pasche Nadine , Wulhfard Sarah , Pretto Francesca , Carugati Elisa , Neri Dario
Published: April 2023

PDF file, 1970KB, Supplementary Material 5. Representative images of immunofluorescence analysis of cryostat section of 6 freshly frozen tumors treated with mIL12-F8-F8 (n = 3) or PBS (n = 3), using as staining reagents (S5.1) anti-CD45 Ab (leukocytes), (S5.2) anti- CD4 Ab (CD4 T cells), (S5.3) anti-CD8 Ab (CD8 T cells), (S5.4) anti-Asialo GM1 (NK cells) or (S5.5) anti-CD31 Ab (blood vessels).
Supplementary Material 4 from The Antibody-Based Delivery of Interleukin-12 to the Tumor Neovasculature Eradicates Murine Models of Cancer in Combination with Paclitaxel
Authors: Pasche Nadine , Wulhfard Sarah , Pretto Francesca , Carugati Elisa , Neri Dario
Published: April 2023

PDF file, 47KB, Supplementary Material 4. P-values of (S4.1) biodistribution studies and (S4.2) therapy experiments.
Related Article from Developing Standards for Breakthrough Therapy Designation in Oncology
Authors: Horning Sandra J. , Haber Daniel A. , Selig Wendy K.D. , Ivy S. Percy , Roberts Samantha A. , Allen Jeff D. , Sigal Ellen V. , Sawyers Charles L.
Published: April 2023

Related Article from Developing Standards for Breakthrough Therapy Designation in Oncology
Supplementary Figure Legends 1-6 from Epigenetic Alteration of PRKCDBP in Colorectal Cancers and Its Implication in Tumor Cell Resistance to TNFα-Induced Apoptosis
Authors: Lee Jin-Hee , Kang Min-Ju , Han Hye-Yeon , Lee Min-Goo , Jeong Seong-In , Ryu Byung-Kyu , Ha Tae-Kyu , Her Nam-Goo , Han Jikhyon , Park Sun Jin , Lee Kil Yeon , Kim Hyo-Jong , Chi Sung-Gil
Published: April 2023

PDF file - 93K
Supplementary Figure 4 from Epigenetic Alteration of PRKCDBP in Colorectal Cancers and Its Implication in Tumor Cell Resistance to TNFα-Induced Apoptosis
Authors: Lee Jin-Hee , Kang Min-Ju , Han Hye-Yeon , Lee Min-Goo , Jeong Seong-In , Ryu Byung-Kyu , Ha Tae-Kyu , Her Nam-Goo , Han Jikhyon , Park Sun Jin , Lee Kil Yeon , Kim Hyo-Jong , Chi Sung-Gil
Published: April 2023

PDF file - 193K
Supplementary Figure 3 from Epigenetic Alteration of PRKCDBP in Colorectal Cancers and Its Implication in Tumor Cell Resistance to TNFα-Induced Apoptosis
Authors: Lee Jin-Hee , Kang Min-Ju , Han Hye-Yeon , Lee Min-Goo , Jeong Seong-In , Ryu Byung-Kyu , Ha Tae-Kyu , Her Nam-Goo , Han Jikhyon , Park Sun Jin , Lee Kil Yeon , Kim Hyo-Jong , Chi Sung-Gil
Published: April 2023

PDF file - 39K
Supplementary Table 2 from The Rectal Cancer microRNAome – microRNA Expression in Rectal Cancer and Matched Normal Mucosa
Authors: Gaedcke Jochen , Grade Marian , Camps Jordi , Søkilde Rolf , Kaczkowski Bogumil , Schetter Aaron J. , Difilippantonio Michael J. , Harris Curtis C. , Ghadimi B. Michael , Møller Søren , Beissbarth Tim , Ried Thomas , Litman Thomas
Published: April 2023

XLS file, 32K, Target sequences for the miRNA PCR reactions.
Supplementary Figure 1 from A Multicenter Phase I Trial of PX-866, an Oral Irreversible Phosphatidylinositol 3-Kinase Inhibitor, in Patients with Advanced Solid Tumors
Authors: Hong David S. , Bowles Daniel W. , Falchook Gerald S. , Messersmith Wells A. , George Goldy C. , O'Bryant Cindy L. , Vo Alex C. H. , Klucher Kevin , Herbst Roy S. , Eckhardt S. Gail , Peterson Scott , Hausman Diana F. , Kurzrock Razelle , Jimeno Antonio
Published: April 2023

PDF file, 70KB, Platelet P-AKT Inhibition.
Supplementary Figure 5 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 50K, Mesenchymal lines are sensitive to Axl inhibition by SGI-7079
Related Article from Therapeutic Drug Monitoring of Imatinib—New Data Strengthen the Case
Authors: Judson Ian
Published: April 2023

Related Article from Therapeutic Drug Monitoring of Imatinib—New Data Strengthen the Case
Related Article from Elusive Extranuclear Estrogen Receptors in Breast Cancer
Authors: Levin Ellis R.
Published: April 2023

Related Article from Elusive Extranuclear Estrogen Receptors in Breast Cancer
Related Article from Regulatory T Cells Move in When Gliomas Say “I DO”
Authors: Choi Bryan D. , Fecci Peter E. , Sampson John H.
Published: April 2023

Related Article from Regulatory T Cells Move in When Gliomas Say “I DO”
Supplementary Figure 1A from Integrated Analysis Reveals Critical Genomic Regions in Prostate Tumor Microenvironment Associated with Clinicopathologic Phenotypes
Authors: Ashida Shingo , Orloff Mohammed S. , Bebek Gurkan , Zhang Li , Zheng Pan , Peehl Donna M. , Eng Charis
Published: April 2023

PDF file - 35K
Supplementary Figure 3 from Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV
Authors: Yoo Ji Young , Pradarelli Jason , Haseley Amy , Wojton Jeffrey , Kaka Azeem , Bratasz Anna , Alvarez-Breckenridge Christopher A. , Yu Jun-Ge , Powell Kimerly , Mazar Andrew P. , Teknos Theodoros N. , Chiocca E. Antonio , Glorioso Joseph C. , Old Matthew , Kaur Balveen
Published: April 2023

PDF file, 304K, Effect of copper on virus therapy for glioma cells.
Supplementary Figure 1 from Pharmacokinetic and Pharmacodynamic Analysis of Circulating Biomarkers of Anti-NRP1, a Novel Antiangiogenesis Agent, in Two Phase I Trials in Patients with Advanced Solid Tumors
Authors: Xin Yan , Li Jessica , Wu Jenny , Kinard Rashell , Weekes Colin D. , Patnaik Amita , LoRusso Patricia , Brachmann Rainer , Tong Raymond K. , Yan Yibing , Watts Ryan , Bai Shuang , Hegde Priti S.
Published: April 2023

PDF file, 57K, Baseline levels of Plasma PlGF for the Phase I study with MNRP1658A and Avf0776 were measured using MSD assay. Equivalent levels and similar distribution of PlGF was observed between the two clinical trials.
Supplementary Table 4 from Targeting the PI3K Pathway in the Brain—Efficacy of a PI3K Inhibitor Optimized to Cross the Blood–Brain Barrier
Authors: Salphati Laurent , Heffron Timothy P. , Alicke Bruno , Nishimura Merry , Barck Kai , Carano Richard A. , Cheong Jonathan , Edgar Kyle A. , Greve Joan , Kharbanda Samir , Koeppen Hartmut , Lau Shari , Lee Leslie B. , Pang Jodie , Plise Emile G. , Pokorny Jenny L. , Reslan Hani Bou , Sarkaria Jann N. , Wallin Jeffrey J. , Zhang Xiaolin , Gould Stephen E. , Olivero Alan G. , Phillips Heidi S.
Published: April 2023

PDF file - 47K, Anti-proliferative EC50's for GNE-317 against a Panel of Nine Glioma Cell lines
Supplementary Figure 1 from Genome-Wide Somatic Copy Number Alterations in Low-Grade PanINs and IPMNs from Individuals with a Family History of Pancreatic Cancer
Authors: Hong Seung-Mo , Vincent Audrey , Kanda Mitsuro , Leclerc Julie , Omura Noriyuki , Borges Michael , Klein Alison P. , Canto Marcia Irene , Hruban Ralph H. , Goggins Michael
Published: April 2023

PDF file, 186KB, Supplemental Figure 1. Copy number alterations in case 1 (PanIN-1). For A-D: The upper, middle and lower panels are the allele ratio, the copy number and the allele-specific ratio, respectively. Each red and blue dot in the lower panel represents allele and the dots are displayed on the panel to indicate the ratio of each allele. A) Lesion 6, PanIN-1, chromosome 1. B) Endocrine neoplasm, chromosome 11.
Supplementary Figures 1-5 from Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor–Induced Tyrosine Kinase Inhibitor Resistance in EGFR Mutant Lung Cancer
Authors: Wang Wei , Li Qi , Takeuchi Shinji , Yamada Tadaaki , Koizumi Hitomi , Nakamura Takahiro , Matsumoto Kunio , Mukaida Naofumi , Nishioka Yasuhiko , Sone Saburo , Nakagawa Takayuki , Uenaka Toshimitsu , Yano Seiji
Published: April 2023

PDF file - 187K
Supplementary Figure Legend from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 68K
Supplementary Table 1 from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 71K, Oligonucleotide sequences
Supplementary Figure 4 from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 48K, Results of the NKp46 demethylation assay performed on HNSCC patient bloods stratified by tumor site
Supplementary Table 4 from ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Authors: Biddlestone-Thorpe Laura , Sajjad Muhammad , Rosenberg Elizabeth , Beckta Jason M. , Valerie Nicholas C.K. , Tokarz Mary , Adams Bret R. , Wagner Alison F. , Khalil Ashraf , Gilfor Donna , Golding Sarah E. , Deb Sumitra , Temesi David G. , Lau Alan , O'Connor Mark J. , Choe Kevin S. , Parada Luis F. , Lim Sang Kyun , Mukhopadhyay Nitai D. , Valerie Kristoffer
Published: April 2023

PDF file - 53K, Preparation of calibration and QC tissue matrix.
Supplementary Tables 1 - 4 from PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer
Authors: Khan Mohammad W. , Keshavarzian Ali , Gounaris Elias , Melson Joshua E. , Cheon Eric C. , Blatner Nichole R. , Chen Zongmin E. , Tsai Fu-Nien , Lee Goo , Ryu Hyunji , Barrett Terrence A. , Bentrem David J. , Beckhove Philipp , Khazaie Khashayarsha
Published: April 2023

PDF file - 61K, Table.1 Patient Cohorts. Table 2. Ulcerative Colitis Patients Absent Colonic Dysplasia. 3.1.3 Ulcerative Colitis patients with invasive cancer used in this study. Table 4. Patients diagnosed with ulcerative colitis and associated colorectal cancers.
Supplementary Table 1 from A Pharmacodynamic/Pharmacokinetic Study of Ficlatuzumab in Patients with Advanced Solid Tumors and Liver Metastases
Authors: Tabernero Josep , Elez Maria Elena , Herranz Maria , Rico Isabel , Prudkin Ludmila , Andreu Jordi , Mateos Jose , Carreras Maria Josep , Han May , Gifford James , Credi Marc , Yin Wei , Agarwal Shefali , Komarnitsky Philip , Baselga Jose
Published: April 2023

PDF file - 57KB, Ficlatuzumab Study P05670. Supplementary Methods for Immunohistochemistry of Tumor Samples.
Supplementary Tables from Common and Complex Notch1 Mutations in Chinese Oral Squamous Cell Carcinoma
Authors: Song Xiaomeng , Xia Ronghui , Li Jiang , Long Zhifeng , Ren Hening , Chen Wantao , Mao Li
Published: April 2023

PDF file 161, the file contains 5 supplemental tables for primers used in the study and detailed information for the mutations identified
Supplementary Figure 4 from PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer
Authors: Khan Mohammad W. , Keshavarzian Ali , Gounaris Elias , Melson Joshua E. , Cheon Eric C. , Blatner Nichole R. , Chen Zongmin E. , Tsai Fu-Nien , Lee Goo , Ryu Hyunji , Barrett Terrence A. , Bentrem David J. , Beckhove Philipp , Khazaie Khashayarsha
Published: April 2023

PDF file - 103K, Multiplex ELISA data for human inflammatory chemoattractants.