bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 - 9, Table 1 from Oncogenic Ras/ERK Signaling Activates CDCP1 to Promote Tumor Invasion and Metastasis
Authors: Uekita Takamasa , Fujii Satoko , Miyazawa Yuri , Iwakawa Reika , Narisawa-Saito Mako , Nakashima Katsuhiko , Tsuta Koji , Tsuda Hitoshi , Kiyono Tohru , Yokota Jun , Sakai Ryuichi
Published: April 2023

PDF file - 330K, Figure S1: Analysis of CDCP1 mRNA expression in non-small cell lung cancer cell-lines. Figure S2: Analysis of CDCP1 mRNA expression in small cell lung cancer cell-lines. Figure S3: Analysis of CDCP1 expression in human lung cancer tissues. Figure S4: Time course analysis of CDCP1 expression treated with PD98059. Figure S5: Ras-ERK signaling is required for CDCP1-dependent anoikis resistance. Figure S6: the 130-kDa and 70-kDa tyrosine phosphorylated proteins are mainly CDCP1 protein. Figure S7: Detection of MMP-2 in HCK cells using Zymogram and anti-MMP-2 antibody. Figure S8: HT1080 cells, A549 cells, and H322Fyn cells with activated Ras attenuated cell invasion treated with MMP-2/MMP-9 inhibitor. Figure S9: MMP-2/MMP-9 inhibitor II did not affect cell proliferation and migration in HCK1T-E-Hras cells, HT1080 cells, A549 cells, and H322Fyn cells with H-Ras-12V.
Supplementary Figure 3 from Anti–miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation
Authors: Wagenaar Timothy R. , Zabludoff Sonya , Ahn Sung-Min , Allerson Charles , Arlt Heike , Baffa Raffaele , Cao Hui , Davis Scott , Garcia-Echeverria Carlos , Gaur Rajula , Huang Shih-Min A. , Jiang Lan , Kim Deokhoon , Metz-Weidmann Christiane , Pavlicek Adam , Pollard Jack , Reeves Jason , Rocnik Jennifer L. , Scheidler Sabine , Shi Chaomei , Sun Fangxian , Tolstykh Tatiana , Weber William , Winter Christopher , Yu Eunsil , Yu Qunyan , Zheng Gang , Wiederschain Dmitri
Published: April 2023

Supplementary Figure 3. HMBG1 and LDH are induced upon miR-21 inhibition. SKHep1, HepG2 and Hep3B cells were treated with anti-miR-21 or MM control and extracellular HMBG1 and LDH activity was quantified. (Mean, {plus minus} SEM, n=3)
Data Supplement from The lncRNA PCAT29 Inhibits Oncogenic Phenotypes in Prostate Cancer
Authors: Malik Rohit , Patel Lalit , Prensner John R. , Shi Yang , Iyer Matthew K. , Subramaniyan Shruthi , Carley Alexander , Niknafs Yashar S. , Sahu Anirban , Han Sumin , Ma Teng , Liu Meilan , Asangani Irfan A. , Jing Xiaojun , Cao Xuhong , Dhanasekaran Saravana M. , Robinson Dan R. , Feng Felix Y. , Chinnaiyan Arul M.
Published: April 2023

Supplementary Figure 3. Expression of PCAT29 in VCaP and LNCaP cells.
Supplementary Figure 8 from Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer
Authors: Bon Hélène , Wadhwa Karan , Schreiner Alexander , Osborne Michelle , Carroll Thomas , Ramos-Montoya Antonio , Ross-Adams Helen , Visser Matthieu , Hoffmann Ralf , Ahmed Ahmed Ashour , Neal David E. , Mills Ian G.
Published: April 2023

Supplementary Figure 8 (Relates to Figure 6) - SIK2 regulates a cell cycle network and a ER stress network related to cancer.
Data Supplement from The lncRNA PCAT29 Inhibits Oncogenic Phenotypes in Prostate Cancer
Authors: Malik Rohit , Patel Lalit , Prensner John R. , Shi Yang , Iyer Matthew K. , Subramaniyan Shruthi , Carley Alexander , Niknafs Yashar S. , Sahu Anirban , Han Sumin , Ma Teng , Liu Meilan , Asangani Irfan A. , Jing Xiaojun , Cao Xuhong , Dhanasekaran Saravana M. , Robinson Dan R. , Feng Felix Y. , Chinnaiyan Arul M.
Published: April 2023

Supplementary Figure 1. Gene sequence information of PCAT29.
Supplementary Figure 7 from Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer
Authors: Bon Hélène , Wadhwa Karan , Schreiner Alexander , Osborne Michelle , Carroll Thomas , Ramos-Montoya Antonio , Ross-Adams Helen , Visser Matthieu , Hoffmann Ralf , Ahmed Ahmed Ashour , Neal David E. , Mills Ian G.
Published: April 2023

Supplementary Figure 7 (Relates to Figure 6) - Validation of microarray hits.
Supplementary Figure 6 from Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer
Authors: Bon Hélène , Wadhwa Karan , Schreiner Alexander , Osborne Michelle , Carroll Thomas , Ramos-Montoya Antonio , Ross-Adams Helen , Visser Matthieu , Hoffmann Ralf , Ahmed Ahmed Ashour , Neal David E. , Mills Ian G.
Published: April 2023

Supplementary Figure 6 (Relates to Figure 5) - SIK2 regulates CREB1 activity via the phosphorylation of TORC2 and TORC3 and their sequestration in the cytoplasm.
Supplementary Material, Figures and Legends from HSF1-Mediated Control of Cellular Energy Metabolism and mTORC1 Activation Drive Acute T-Cell Lymphoblastic Leukemia Progression
Authors: Eroglu Binnur , Pang Junfeng , Jin Xiongjie , Xi Caixia , Moskophidis Demetrius , Mivechi Nahid F.
Published: April 2023

Figure S1. Hsf1 loss significantly reduced human T-ALL cell survival. Figure S2. Pharmacological inhibitors of the HSF1 pathway exhibit potent antitumor activity in human T-ALL cell lines. Figure S3. HSF1 knockdown in human T-ALL cell lines reduces the mitochondrial membrane potential and increases cellular ROS levels.
Supplemental Table S1 from RSK Promotes Prostate Cancer Progression in Bone through ING3, CKAP2, and PTK6-Mediated Cell Survival
Authors: Yu Guoyu , Lee Yu-Chen , Cheng Chien-Jui , Wu Chuan-Fen , Song Jian H. , Gallick Gary E. , Yu-Lee Li-Yuan , Kuang Jian , Lin Sue-Hwa
Published: April 2023

Oligonucleotides of primers.
Supplementary Figure 3 from Salt-Inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer
Authors: Bon Hélène , Wadhwa Karan , Schreiner Alexander , Osborne Michelle , Carroll Thomas , Ramos-Montoya Antonio , Ross-Adams Helen , Visser Matthieu , Hoffmann Ralf , Ahmed Ahmed Ashour , Neal David E. , Mills Ian G.
Published: April 2023

Supplementary Figure 3 (Relates to Figure 4) - SIK2 knock-down induces a cell cycle arrest in G1 phase and delays mitotic progression of LNCaP cells.
Supplementary Figures 1-9, Supplementary Table 1 from Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib
Authors: Wang Zhaohui , Xu Cheng , Diplas Bill H. , Moure Casey J. , Chen Chin-Pu Jason , Chen Lee H. , Du Changzheng , Zhu Huishan , Greer Paula K. , Zhang Liwei , He Yiping , Waitkus Matthew S. , Yan Hai
Published: April 2023

Supplementary Fig. 1. Confirmation of SF7761 derived PPM1D-/- clones by Sanger sequencing. Supplementary Fig. 2. Effect of DNA repair inhibitors on cell viability in SF7761 parental and PPM1D-/- clones. Supplementary Fig. 3. GSK2830371 treatment synergizes with olaparib in PPM1D-mutant DIPG cells. Supplementary Fig. 4. Combination treatment low-dose GSK2830371 and olaparib in TT10714. Supplementary Fig. 5. Matrix plots representation of relative cell viabilities treated with indicated concentrations of olaparib and GSK2830371 for 7 days. Supplementary Fig. 6. 3D spheroid invasion assay performed to assess the growth and invasive potential of TT10714 cells upon single-agent or combination treatments. Supplementary Fig. 7. 3D spheroid invasion assay performed to assess 3D spheroid growth and invasive potential of SF7761 cells upon single-agent or combination treatments. Supplementary Fig. 8. 3D spheroid invasion assay performed to assess 3D spheroid growth and invasive potential of HSJD-DIPG-007 cells upon single-agent or combination treatments. Supplementary Fig. 9. Analysis of 53BP1 foci in response to PPM1D genetic inhibition and olaparib treatment. Supplementary Table 1. Oligos and Primer sequences.
Supplementary Figure Legends from Radiation Attenuates Prostate Tumor Antiviral Responses to Vesicular Stomatitis Virus Containing IFNβ, Resulting in Pronounced Antitumor Systemic Immune Responses
Authors: Udayakumar Thirupandiyur S. , Betancourt Dillon M. , Ahmad Anis , Tao Wensi , Totiger Tulasigeri M. , Patel Mausam , Marples Brian , Barber Glen , Pollack Alan
Published: April 2023

S1. VSV-hIFNβ treatment followed by RT caused S-phase cell cycle arrest of prostate cancer cells. S2. VSV treatment in combination with radiation therapy increases the GFP or Luciferase expression in vitro and in vivo. S3. C57BL/6 CD8 Re-challenge study with VSV-mIFNβ+RT followed by CD8 depletion.
Supplemental Figure 4 from lincRNA-RoR and miR-145 Regulate Invasion in Triple-Negative Breast Cancer via Targeting ARF6
Authors: Eades Gabriel , Wolfson Benjamin , Zhang Yongshu , Li Qinglin , Yao Yuan , Zhou Qun
Published: April 2023

Supplemental Figure 4. lincRNA-ROR/miR-145/ARF6 axis regulates tumor cell invasion in TNBC cells. A, Transwell invasion assay for MCF-7 cells transfected with tet-ON-lincRNA-ROR + rtTA and induced with 100ng/mL Dox. B, Western blot for ARF6 in MDA-MB-231 cells infected with scrambled shRNA or shRNA for linc-RNA-ROR.
Supplementary Materials and Methods from AGO2 Mediates MYC mRNA Stability in Hepatocellular Carcinoma
Authors: Zhang Kai , Pomyen Yotsawat , Barry Anna E. , Martin Sean P. , Khatib Subreen , Knight Lucy , Forgues Marshonna , Dominguez Dana A. , Parhar Ravinder , Shah Ashesh P. , Bodzin Adam S. , Wang Xin Wei , Dang Hien
Published: April 2023

Supplementary Materials and Methods
Supplementary Tables 1-3 from Telomere-Regulating Genes and the Telomere Interactome in Familial Cancers
Authors: Robles-Espinoza Carla Daniela , del Castillo Velasco-Herrera Martin , Hayward Nicholas K. , Adams David J.
Published: April 2023

Supplementary Tables 1-3. Supplementary Table 1. Proteins part of the telomerase or shelterin complexes and associated diseases. Supplementary Table 2. Proteins part of the telomere interactome, interacting partners and associated disorders. Supplementary Table 3. Telomere syndromes and associated characteristics.
Supplementary Figure 2 from Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma
Authors: Gil del Alcazar Carlos Rodrigo , Todorova Pavlina Krasimirova , Habib Amyn A. , Mukherjee Bipasha , Burma Sandeep
Published: April 2023

Supplemental Figure 2. A-D. Primary (483 and 484) and recurrent (419 and 481) cultures were assessed by colony survival assays using the indicated doses of A) IR , B) ETO, C) MNNG, or D) CPT. The fraction of surviving colonies (y-axis) is plotted against the corresponding dose of the genotoxic agent (x-axis). Error bars, S.D. ****, p<0.0001
Data Supplement from The Lipid Kinase PI4KIIIβ Is Highly Expressed in Breast Tumors and Activates Akt in Cooperation with Rab11a
Authors: Morrow Anne A. , Alipour Mohsen Amir , Bridges Dave , Yao Zemin , Saltiel Alan R. , Lee Jonathan M.
Published: April 2023

Supplementary Figure 4
Supplementary Tables 1-3 from Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma
Authors: Li Qingguo , Qin Yi , Wei Ping , Lian Peng , Li Yaqi , Xu Ye , Li Xinxiang , Li Dawei , Cai Sanjun
Published: April 2023

Supplementary Tables 1-3
Figure S7 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
Authors: Dambal Shweta , Alfaqih Mahmoud , Sanders Sergio , Maravilla Erick , Ramirez-Torres Adela , Galvan Gloria C. , Reis-Sobreiro Mariana , Rotinen Mirja , Driver Lucy M. , Behrove Matthew S. , Talisman Tijana Jovanovic , Yoon Junhee , You Sungyong , Turkson James , Chi Jen-Tsan , Freeman Michael R. , Macias Everardo , Freedland Stephen J.
Published: April 2023

Scanned uncropped western blot films
Figure S4 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
Authors: Dambal Shweta , Alfaqih Mahmoud , Sanders Sergio , Maravilla Erick , Ramirez-Torres Adela , Galvan Gloria C. , Reis-Sobreiro Mariana , Rotinen Mirja , Driver Lucy M. , Behrove Matthew S. , Talisman Tijana Jovanovic , Yoon Junhee , You Sungyong , Turkson James , Chi Jen-Tsan , Freeman Michael R. , Macias Everardo , Freedland Stephen J.
Published: April 2023

DU145 27HC effects on Boyden chamber transwell assay
supp figure legends from Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelial–Mesenchymal Transition: Effects on Anoikis
Authors: Farris Joshua C. , Pifer Phillip M. , Zheng Liang , Gottlieb Eyal , Denvir James , Frisch Steven M.
Published: April 2023

supplementary figure legends
Table S1 from DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 Status
Authors: Kataoka Yuki , Iimori Makoto , Fujisawa Ryo , Morikawa-Ichinose Tomomi , Niimi Shinichiro , Wakasa Takeshi , Saeki Hiroshi , Oki Eiji , Miura Daisuke , Tsurimoto Toshiki , Maehara Yoshihiko , Kitao Hiroyuki
Published: April 2023

The list of antibodies used in this study.
Table S1 from OLR1 Promotes Pancreatic Cancer Metastasis via Increased c-Myc Expression and Transcription of HMGA2
Authors: Yang Gang , Xiong Guangbing , Feng Mengyu , Zhao Fangyu , Qiu Jiangdong , Liu Yueze , Cao Zhe , Wang Huanyu , Yang Jinshou , You Lei , Zheng Lianfang , Zhang Taiping , Zhao Yupei
Published: April 2023

The differential expression of genes in cells with OLR1 knocked down.
Supplementary Materials from OLR1 Promotes Pancreatic Cancer Metastasis via Increased c-Myc Expression and Transcription of HMGA2
Authors: Yang Gang , Xiong Guangbing , Feng Mengyu , Zhao Fangyu , Qiu Jiangdong , Liu Yueze , Cao Zhe , Wang Huanyu , Yang Jinshou , You Lei , Zheng Lianfang , Zhang Taiping , Zhao Yupei
Published: April 2023

The supplemental figures and the sequences of primers and siRNAs. Figure S1. Verification of OLR1 expression in mice model. Figure S2. OLR1 promotes the metastasis of PC cells in intravenous mouse models. Figure S3. OLR1 increases the expression of c-Myc and HMGA2 to promote invasion and migration of PC cells. Figure S4. c-Myc promotes the transcription of HMGA2. Figure S5. OLR1 upregulates HMGA2 through c-Myc to promote PC cells metastasis. Figure S6. The relationship of OLR1, c-Myc and HMGA2 in xenograft tumors. Figure S7. High OLR1, c-Myc and HMGA2 expression is associated with poor prognosis of PC patients.
Supplementary Figures 1-7 from A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells
Authors: Song Jing , Du Zhanwen , Ravasz Mate , Dong Bohan , Wang Zhenghe , Ewing Rob M.
Published: April 2023

Supplementary Figures 1-7. Supplementary Figure 1.Cell-cycle profiles of HEK293T cells following treatment with Wnt3a. Supplementary Figure 2. Protein lysate samples used in the immunoprecipitation or immunoblots analyses were treated with Nuclease. Supplementary Figure 3. Dnmt1 (native antibody) immuno-precipitates β-catenin in parent HCT116 cells. Supplementary Figure 4. DNMT1 protein is stabilized by treatment with Wnt3a in HCT116 but not in CTNNB1KO-HCT116 cells. Supplementary Figure 5. Degradation profiles for β-catenin and Dnmt1 in HCT116, DNMT1KO-HCT116 or CTNNB1KO-HCT116 cells following cycloheximide treatment. Supplementary Figure 6. Abundance of β-catenin and Dnmt1 in DNMT1KO-HCT116 (A) or CTNNB1KO-HCT116 (B) cells treated with MG-132 proteasome inhibitor. Supplementary Figure 7. RT-PCR analysis of H19 expression in HCT116 and CTNNB1KO-HCT116 cells shows increase H19 transcript levels in the KO cells.
Supplementary Information 1 from Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial–Mesenchymal Transition–like Process and 22q Loss
Authors: Stacchiotti Silvia , Astolfi Annalisa , Gronchi Alessandro , Fontana Andrea , Pantaleo Maria A. , Negri Tiziana , Brenca Monica , Tazzari Marcella , Urbini Milena , Indio Valentina , Colombo Chiara , Radaelli Stefano , Brich Silvia , Dei Tos Angelo P. , Casali Paolo G. , Castelli Chiara , Dagrada Gian Paolo , Pilotti Silvana , Maestro Roberta
Published: April 2023

Supplemental methodological information
Supplementary Figure 4 from Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial–Mesenchymal Transition–like Process and 22q Loss
Authors: Stacchiotti Silvia , Astolfi Annalisa , Gronchi Alessandro , Fontana Andrea , Pantaleo Maria A. , Negri Tiziana , Brenca Monica , Tazzari Marcella , Urbini Milena , Indio Valentina , Colombo Chiara , Radaelli Stefano , Brich Silvia , Dei Tos Angelo P. , Casali Paolo G. , Castelli Chiara , Dagrada Gian Paolo , Pilotti Silvana , Maestro Roberta
Published: April 2023

Expression analysis (qRT-PCR) of H19, HOTAIR and EZH2 in DFSP and FS-DFSP samples. Statistical p values (unpaired Student's t test) are indicated.
Supplementary Figure 3 from Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial–Mesenchymal Transition–like Process and 22q Loss
Authors: Stacchiotti Silvia , Astolfi Annalisa , Gronchi Alessandro , Fontana Andrea , Pantaleo Maria A. , Negri Tiziana , Brenca Monica , Tazzari Marcella , Urbini Milena , Indio Valentina , Colombo Chiara , Radaelli Stefano , Brich Silvia , Dei Tos Angelo P. , Casali Paolo G. , Castelli Chiara , Dagrada Gian Paolo , Pilotti Silvana , Maestro Roberta
Published: April 2023

A) DFSP (case D8) hybridized with PDGF break apart approach (centromeric end in Spectrum Orange, telomeric end in Spectrum Green).Two fusion signals are visible (untranslocated copies of PDGFB) together with 2 free red signals (corresponding to the translocated alleles). B) PDGFB break apart FISH pattern of a FS-DFSP (case D9) showing a single fusion signal and 2 free red signals.
Supplementary Figure 1 from Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial–Mesenchymal Transition–like Process and 22q Loss
Authors: Stacchiotti Silvia , Astolfi Annalisa , Gronchi Alessandro , Fontana Andrea , Pantaleo Maria A. , Negri Tiziana , Brenca Monica , Tazzari Marcella , Urbini Milena , Indio Valentina , Colombo Chiara , Radaelli Stefano , Brich Silvia , Dei Tos Angelo P. , Casali Paolo G. , Castelli Chiara , Dagrada Gian Paolo , Pilotti Silvana , Maestro Roberta
Published: April 2023

Principal Component Analysis of DFSP and FS-DFSP gene expression profiles.
Supplementary Figure from miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1
Authors: Sakaguchi Masazumi , Hisamori Shigeo , Oshima Nobu , Sato Fumiaki , Shimono Yohei , Sakai Yoshiharu
Published: April 2023

Supplementary Fig. S1. (A): Immunohistochemical analysis of other human normal colon and colon cancer specimens. DCLK1-positive epithelial cells were not found at the crypt bottoms. Normal tissues are partially positive but cancer tissues were widely positive for DCLK1. Scale bar: 100 Î¼m. (B): Representative metastatic lymph node. DCLK1-positive cells were dominant in the metastatic lymph node. Scale bar: 100 Î¼m. Supplementary Fig. S2. (A): SW480 cells are EpCAM-positive and low CD66a expression. (B): Representative flow cytometry plot. GFP+/mCherry+/CD44+ SW480 cells were collected by flow cytometry. (C): DCLK1 expression was suppressed in the SW480 cells transduced with the pGIPZ lentiviral shRNA against DCLK1. (D): (Top) Representative images of the organoids. The left and middle panels are the fluorescent microscopic images for the detection of GFP and mCherry, respectively. The right panels are the phase-contrast images of the organoids merged with the images of the green fluorescent images (left) and the red fluorescent images (middle). Scale bar: 100 Î¼m. (Bottom) Co-expression of the exogenous DCLK1 substantially rescued the defect in organoid formation of shDCLK1-SW480 cells (*p<0.05). Supplementary Fig. S3. (A): Almost all hPCCs express EpCAM. (B): MiR-137 knockdown enhanced expression of DCLK1 of GFP+/EpCAM+/CD44+/CD66a- hPCCs. (C): Aline the two sequences between human DCLK1 and murine Dclk1. Target 1 of human DCLK1 is preserved. Supplementary Fig. S4. (A): GFP+/CD44+ SW480 cells were sorted by flow cytometry and 2.0 Ã— 106 cells were injected subcutaneously into immunodeficient mice. The tumor volume and incidence at eight weeks after injection into nude mice (top) or NOD/SCID mice (bottom) (*p<0.05). (B): MiR-137 does not affect the proliferation of SW480 cells.
Supplementary Figures 1 - 5, Tables 1 - 4 from WHSC1 Promotes Oncogenesis through Regulation of NIMA-Related Kinase-7 in Squamous Cell Carcinoma of the Head and Neck
Authors: Saloura Vassiliki , Cho Hyun-Soo , Kiyotani Kazuma , Alachkar Houda , Zuo Zhixiang , Nakakido Makoto , Tsunoda Tatsuhiko , Seiwert Tanguy , Lingen Mark , Licht Jonathan , Nakamura Yusuke , Hamamoto Ryuji
Published: April 2023

Figure S1. Chromatin immunoprecipitation assays (ChIP) performed in UD-SCC-2 cells treated with siWHSC1 for 3 days. Real-time PCR analysis was conducted using primer pairs as described under "Materials and Methods". Immunoprecipitation was performed with ChIP grade anti-H3K36me2 (Millipore, 07-369) antibodies. Y-axis shows a percentage of the input chromatin. Results are the mean {plus minus}SD of three independent experiments, and P-values were calculated using Student's t-test (n.s.: not significant). Figure S2. WHSC1 protein expression of three SCCHN (FaDu, HN-5 and 93VU147T) cells. Nuclear extracts were immunoblotted with anti-WHSC1 (Abcam, ab75359) and anti-histone H3 (Abcam, ab1791) antibodies. Histone H3 was served as an internal control. Figure S3. Heatmap of down regulated-genes at 48 h and 72 h of WHSC1 knockdown in UD-SCC-2 cells. Figure S4. Validation of WHSC1, HIK3 and MAPK8 expressions in HPV-positive (UD-SCC-2) cells by quantitative real-time PCR 48 or 72 h after treatment with siRNAs. Figure S5. Cross-cancer alteration summary for NEK7. The data were obtained from the TCGA database (http://www.cbioportal.org/public-portal/). Table S1. Characteristics of SCCHN cell lines. Table S2. Primer Sequences for Quantitative RT-PCR. Table S3. siRNA Sequences. Table S4. Gene Ontology analysis of candidate genes.
Table S3 from miR-29a Is Repressed by MYC in Pancreatic Cancer and Its Restoration Drives Tumor-Suppressive Effects via Downregulation of LOXL2
Authors: Dey Shatovisha , Kwon Jason J. , Liu Sheng , Hodge Gabriel A. , Taleb Solaema , Zimmers Teresa A. , Wan Jun , Kota Janaiah
Published: April 2023

Panc-1 and MIA PaCa-2 overlapping down- and upregulated target genes with qPCR validation data.
Table S2 from miR-29a Is Repressed by MYC in Pancreatic Cancer and Its Restoration Drives Tumor-Suppressive Effects via Downregulation of LOXL2
Authors: Dey Shatovisha , Kwon Jason J. , Liu Sheng , Hodge Gabriel A. , Taleb Solaema , Zimmers Teresa A. , Wan Jun , Kota Janaiah
Published: April 2023

Panc-1 and MIA PaCa-2 overlapping miR-29a target genes.
Figure S8 from CD44 Regulates Formation of Spheroids and Controls Organ-Specific Metastatic Colonization in Epithelial Ovarian Carcinoma
Authors: Sacks Suarez Joelle , Gurler Main Hilal , Muralidhar Goda G. , Elfituri Osama , Xu Hao-Liang , Kajdacsy-Balla Andre A. , Barbolina Maria V.
Published: April 2023

SUPPLEMENTARY FIGURE 8. Effect of CD44 silencing on ES2 - athymic nude mice xenograft model survival.
Supplemental Figure 4 from The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression
Authors: Rabender Christopher S. , Alam Asim , Sundaresan Gobalakrishnan , Cardnell Robert J. , Yakovlev Vasily A. , Mukhopadhyay Nitai D. , Graves Paul , Zweit Jamal , Mikkelsen Ross B.
Published: April 2023

Supplemental Figure 4: shows the response of MDA-231 xenografts to >30 days treatment with SP in terms of tumor growth measured as tumor volumes and by a Kaplan Meier analysis of animal survival.
Supplemental Figure 3 from The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression
Authors: Rabender Christopher S. , Alam Asim , Sundaresan Gobalakrishnan , Cardnell Robert J. , Yakovlev Vasily A. , Mukhopadhyay Nitai D. , Graves Paul , Zweit Jamal , Mikkelsen Ross B.
Published: April 2023

Supplemental Figure 3: compares the effects of two NOS inhibitors on SP-increased cGMP in MCF-7 and MDA-231 cells.
Fig. S3. Validation of CX3CR1 silencing by CRISPRi in animal tumors. from Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells
Authors: Shen Fei , Zhang Yun , Jernigan Danielle L. , Feng Xin , Yan Jie , Garcia Fernando U. , Meucci Olimpia , Salvino Joseph M. , Fatatis Alessandro
Published: April 2023

Tissue specimens harvested by Laser Capture Microdissection from skeletal tumors generated in mice were tested for CX3CR1 expression at the transcriptional level by qRT-PCR. The results confirm the almost complete gene silencing achieved using CRISPRi.
Figure S4 from Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms
Authors: Qian Yanrong , Wang Xuan , Li Yunsheng , Cao Yanyang , Chen Xiaozhuo
Published: April 2023

Fig. S4. Quantification of internalized fluorescent dextran or NHF-ATP in A549 cells treated with different endocytosis inhibitors.
FIg. S2. Effects of CX3CR1 antagonism on migration of breast cancer cells. from Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells
Authors: Shen Fei , Zhang Yun , Jernigan Danielle L. , Feng Xin , Yan Jie , Garcia Fernando U. , Meucci Olimpia , Salvino Joseph M. , Fatatis Alessandro
Published: April 2023

In chemotaxis experiments, cancer cells were plated in the upper chamber in the absence or presence of JMS-17-2, with the lower chamber containing 50nM FKN. The CX3CR1 antagonist inhibited the migration of cancer cells in a dose-dependent manner. ** p=0.07; *** p=<0.0001.
Figure S3 from Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms
Authors: Qian Yanrong , Wang Xuan , Li Yunsheng , Cao Yanyang , Chen Xiaozhuo
Published: April 2023

Fig. S3. Colocalization of HMWFD and LMWFD in A549 and H1299 NSCLC cells.
Supplementary Data, Tables 1-7, Supplementary Figures 1-11 from Secreted Factors from Adipose Tissue Reprogram Tumor Lipid Metabolism and Induce Motility by Modulating PPARα/ANGPTL4 and FAK
Authors: Blücher Christina , Iberl Sabine , Schwagarus Nancy , Müller Silvana , Liebisch Gerhard , Höring Marcus , Hidrobo Maria Soledad , Ecker Josef , Spindler Nick , Dietrich Arne , Burkhardt Ralph , Stadler Sonja C.
Published: April 2023

Table S1: Primersequences used for human and murine cell lines. Table S2: Upstream regulators of genes with increased expression in MDA-MB-231 cells co-cultured with murine adipose tissue (HFD). Table S3: Upstream regulators of genes with decreased expression in MDA-MB-231 cells co-cultured with murine adipose tissue (HFD). Table S4: Characterization of the free fatty acid profile of ACMs<30 and ACMs>40. Table S5: Enriched GO terms (Biological Process) in genes with {greater than or equal to}1.5-fold downregulation in MDAMB-231 cells co-cultured with adipose tissue of HFD mice vs control. Table S6: Enriched GO terms (Biological Process) in genes with {greater than or equal to}1.5-fold upregulation in MDA-MB231 cells co-cultured with adipose tissue of HFD mice vs control. Fig. S1: Pathway Analysis and gene expression data of co-cultured MDA-MB-231 cells. Fig. S2: ACM increases PPAR target gene expression in murine E0771 cells. Fig. S3: ANGPTL4 mRNA is increased in human triple negative breast cancer and associated with reduced survival. Fig. S4: PPAR target gene expression is dependent on PPARα. Fig. S5: Free fatty acids activate PPAR signaling in TNBC cells. Fig. S6: Incubation of TNBC cells with ACM or BSA-OA decreases de novo FA synthesis. Fig. S7: Cultivation of TNBC cells with ACM or BSA-OA induces the expression of β-oxidation genes. Fig. S8: Treatment with oleic acid increases intracellular lipid droplet formation in TNBC cells. Fig S9: ACM promotes proliferation and migration of E0771 cells. Fig. S10: ANGPTL4 knockdown in MDA-MB-231 cells does not affect cell proliferation. Fig. S11: MMP2 is upregulated in MDA-MB-231 cells upon ACM cultivation.
Supplementary Table S1 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Karpf HGSC and Patient-matched OSE and FTE Sample Information and Methylation Analyses Performed.
Figure S7 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Bowtell 450K data principal component analyses (PCA).
Supplemental Figure Legend from LEF1 Targeting EMT in Prostate Cancer Invasion Is Regulated by miR-34a
Authors: Liang Jiaqian , Li Yirong , Daniels Garrett , Sfanos Karen , De Marzo Angelo , Wei Jianjun , Li Xin , Chen Wenqiang , Wang Jinhua , Zhong Xuelin , Melamed Jonathan , Zhao Jun , Lee Peng
Published: April 2023

Supplemental Figure Legend
Figure S6 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Bowtell 450K Pearson correlation coefficient analysis.
Figure S2 from DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-Grade Serous Ovarian Cancer
Authors: Klinkebiel David , Zhang Wa , Akers Stacey N. , Odunsi Kunle , Karpf Adam R.
Published: April 2023

Karpf 450K data principal component analyses (PCA).
Supplemental Figure 5 from Identification of TRIML2, a Novel p53 Target, that Enhances p53 SUMOylation and Regulates the Transactivation of Proapoptotic Genes
Authors: Kung Che-Pei , Khaku Sakina , Jennis Matthew , Zhou Yan , Murphy Maureen E.
Published: April 2023

Figure S5. TRIML2 regulates a subset of p53 target genes.
Supplementary Figure 1 from Decreased eIF3e Expression Can Mediate Epithelial-to-Mesenchymal Transition through Activation of the TGFβ Signaling Pathway
Authors: Desnoyers Guillaume , Frost Laura D. , Courteau Lynn , Wall Michael L. , Lewis Stephen M.
Published: April 2023

Supplementary Figure 1- Total RNA was extracted from A549 cells harboring the β-galactosidase/CAT bicistronic reporter plasmid in which the 5' UTRs of the SNAI1, ZEB2, VIM, TGFB1 or c-MYC mRNA were cloned into the intercistronic region. The expression level of CAT and βgal was measured by qRT-PCR.
Supplementary File 5 from Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
Authors: Jane Esther P. , Premkumar Daniel R. , Thambireddy Swetha , Golbourn Brian , Agnihotri Sameer , Bertrand Kelsey C. , Mack Stephen C. , Myers Max I. , Chattopadhyay Ansuman , Taylor D. Lansing , Schurdak Mark E. , Stern Andrew M. , Pollack Ian F.
Published: April 2023

Supplemental File 5
Supplemental Figures S1-S7 from Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44
Authors: Hartmann Monika , Parra Liseth M. , Ruschel Anne , Böhme Sandra , Li Yong , Morrison Helen , Herrlich Andreas , Herrlich Peter
Published: April 2023

Supplemental Figures S1-S7: Supplemental Figure S1: The effect of γ-secretase inhibition on ectodomain cleavage Supplemental Figure S2. Regulated cleavage targets substrates after surface expression Supplemental Figure S3: Interaction between CD44 and Merlin. Supplemental Figure S4: The tumor suppressor merlin (Nf2) inhibits CD44 cleavage. Supplemental Figure S5. Exemplified analysis of the constructs used in the migration assay of Figure 7A and Supplemental Figure 6 Supplemental Figure S6: Examplified photographs of one of the scratch assays with MEFs as shown in Figure 7A. Supplemental Figure S7: Loading diagrams of Figures 3B and 4C
Supplementary Figure 7 from Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
Authors: Jane Esther P. , Premkumar Daniel R. , Thambireddy Swetha , Golbourn Brian , Agnihotri Sameer , Bertrand Kelsey C. , Mack Stephen C. , Myers Max I. , Chattopadhyay Ansuman , Taylor D. Lansing , Schurdak Mark E. , Stern Andrew M. , Pollack Ian F.
Published: April 2023

Supplemental Figure 7. Bar graph showing QPRT mRNA expression levels (absolute value) between drug naive and panobinostat + bortezomib resistant DIPG 007, SJG 2 and U87 cells.
Supplementary Figure 2 from Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
Authors: Jane Esther P. , Premkumar Daniel R. , Thambireddy Swetha , Golbourn Brian , Agnihotri Sameer , Bertrand Kelsey C. , Mack Stephen C. , Myers Max I. , Chattopadhyay Ansuman , Taylor D. Lansing , Schurdak Mark E. , Stern Andrew M. , Pollack Ian F.
Published: April 2023

Supplemental Figure 2. Drug naive U87 or panobinostat-resistant, bortezomib-resistant or panobinostat and bortezomib-resistant cells were treated with the combination of panobinostat (25 nmol/L) plus bortezomib (2.5 nmol/L) for 24 h.
Table S2 from Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer
Authors: Kim Jae-Young , Welsh Eric A. , Fang Bin , Bai Yun , Kinose Fumi , Eschrich Steven A. , Koomen John M. , Haura Eric B.
Published: April 2023

Table S2. List of selumitinib-regulated phosphopeptides generated by statistical filtering.
Supplementary Legends from Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer
Authors: Kim Jae-Young , Welsh Eric A. , Fang Bin , Bai Yun , Kinose Fumi , Eschrich Steven A. , Koomen John M. , Haura Eric B.
Published: April 2023

Supplementary Figure Legends
Supplementary Table 5 from Tumor Cell–Derived MMP3 Orchestrates Rac1b and Tissue Alterations That Promote Pancreatic Adenocarcinoma
Authors: Mehner Christine , Miller Erin , Khauv Davitte , Nassar Aziza , Oberg Ann L. , Bamlet William R. , Zhang Lizhi , Waldmann Jens , Radisky Evette S. , Crawford Howard C. , Radisky Derek C.
Published: April 2023

XLSX file - 364K, Supplemental Table 5. Overlap of genes between MMP-3-treated cells and TGFbeta-treated cells.
Supplementary Table 3 from Tumor Cell–Derived MMP3 Orchestrates Rac1b and Tissue Alterations That Promote Pancreatic Adenocarcinoma
Authors: Mehner Christine , Miller Erin , Khauv Davitte , Nassar Aziza , Oberg Ann L. , Bamlet William R. , Zhang Lizhi , Waldmann Jens , Radisky Evette S. , Crawford Howard C. , Radisky Derek C.
Published: April 2023

XLSX file - 59K, Supplemental Table 3. Gene expression changes in response to MMP-3 treatment.
supplemental figure 4 from SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism
Authors: Hoang Bao , Shi Yijiang , Frost Patrick J. , Mysore Veena , Bardeleben Carolyne , Lichtenstein Alan
Published: April 2023

Suppl fig 4: Lysate harvested from tumors of mice challenged with EV- or SGK-transfected tumors and treated with 0, 0.5 or 1 mg/kg Bortezomib; Lysates are combined from 3 mice/group and harvested 1 week after initiating treatment (mice had received 2 treatments); IKB-alpha then immunoprecipitated from lysates and immunoblotted for IKB as well as ubiquitin;
supplemental figure 3 from SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism
Authors: Hoang Bao , Shi Yijiang , Frost Patrick J. , Mysore Veena , Bardeleben Carolyne , Lichtenstein Alan
Published: April 2023

Suppl fig 3: A) MM1.S or 8226 cells lines transfected with empty vector (EV), wild type SGK (sgk) or phosphomimetic SGK (sgk422D) and cultured in serum free media for days 1-7. At designated days, apoptosis assay performed. Data are percent apoptosis, mean+/-SE, n=5; B) MM1.S or OPM-2 cell lines similarly transfected as in A were exposed to dexamethasone for 72 hrs followed by MTT assay. Data are mean cell survival+/-SE, n=4.
Supplementary Materials and Methods, Figure Legends from VDR Status Arbitrates the Prometastatic Effects of Tumor-Associated Macrophages
Authors: Zhang Yan , Guo Quanjun , Zhang Zhujun , Bai Nan , Liu Ze , Xiong Min , Wei Yuquan , Xiang Rong , Tan Xiaoyue
Published: April 2023

PDF file - 286KB
Supplementary Table 5 from Convergent and Divergent Cellular Responses by ErbB4 Isoforms in Mammary Epithelial Cells
Authors: Wali Vikram B. , Haskins Jonathan W. , Gilmore-Hebert Maureen , Platt James T. , Liu Zongzhi , Stern David F.
Published: April 2023

XLSX file - 169KB, ChIP Seq-RNA Overlapping genes.
Supplementary Figure 2 from Convergent and Divergent Cellular Responses by ErbB4 Isoforms in Mammary Epithelial Cells
Authors: Wali Vikram B. , Haskins Jonathan W. , Gilmore-Hebert Maureen , Platt James T. , Liu Zongzhi , Stern David F.
Published: April 2023

PDF file - 89KB, Genes altered by expressing ERBB4 isoforms.
Supplementary Video 2 from Urothelial Carcinoma of the Bladder Induces Endothelial Cell Activation and Hypercoagulation
Authors: John Axel , Robador José R. , Vidal-y-Sy Sabine , Houdek Pia , Wladykowski Ewa , Günes Cagatay , Bolenz Christian , Schneider Stefan W. , Bauer Alexander T. , Gorzelanny Christian
Published: April 2023

Supernatants of RT4 cells induced endothelial activation. Calcein blue labeled HUVECs (blue) were perfused with calcein red-orange labeled platelets (red) resuspended in cell culture medium conditioned by RT4 cells.
Supplementary Table 3 from Prognostic Potential of DNA Methylation and Transcript Levels of HIF1A and EPAS1 in Colorectal Cancer
Authors: Rawłuszko-Wieczorek Agnieszka Anna , Horbacka Karolina , Krokowicz Piotr , Misztal Matthew , Jagodziński Paweł Piotr
Published: April 2023

PDF file - 41K, DNA metylation level of EPAS1 gene regulatory region in primary cancerous tissue and histopathologically unchanged tissue sample according to subgroup- stratified patients with CRC.
Table S1 and S3 through S10 from Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor
Authors: Dorr Casey , Janik Callie , Weg Madison , Been Raha A. , Bader Justin , Kang Ryan , Ng Brandon , Foran Lindsey , Landman Sean R. , O'Sullivan M. Gerard , Steinbach Michael , Sarver Aaron L. , Silverstein Kevin A.T. , Largaespada David A. , Starr Timothy K.
Published: April 2023

Supplemental Tables S1 and S3 through S10. Table S1: Percentage of experimental animals with abnormal growths in tissues other than the lungs Table S3: Candidate Lung Cancer Genes based on CIS. Table S4: CIS human ortholog overlap with human cancer genes. Table S5: Ingenuity Pathway Analysis significant canonical pathways with 3 or more molecules. Table S6: Sets of genes with transposon insertions in multiple mice based on frequent itemset mining. Table S7: Differentially expressed genes in A549 cells with CUL3, PTEN, or CUL3 and PTEN knocked down. Table S8: NRF2 pathway genes differentially expressed in A549 CUL3/PTEN knockdown cells. Table S9: Top 50 canonical pathways enriched for significantly altered genes in CUL3/PTEN knockdown cells compared to controls. Table S10: Top 50 canonical pathways enriched for significantly altered genes in CUL3 knockdown cells compared to controls.
Supplemental Table S2 from Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor
Authors: Dorr Casey , Janik Callie , Weg Madison , Been Raha A. , Bader Justin , Kang Ryan , Ng Brandon , Foran Lindsey , Landman Sean R. , O'Sullivan M. Gerard , Steinbach Michael , Sarver Aaron L. , Silverstein Kevin A.T. , Largaespada David A. , Starr Timothy K.
Published: April 2023

Supplemental Table S2 containing list of insertions
Supplemental Information from Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor
Authors: Dorr Casey , Janik Callie , Weg Madison , Been Raha A. , Bader Justin , Kang Ryan , Ng Brandon , Foran Lindsey , Landman Sean R. , O'Sullivan M. Gerard , Steinbach Michael , Sarver Aaron L. , Silverstein Kevin A.T. , Largaespada David A. , Starr Timothy K.
Published: April 2023

Supplemental Methods
Supplementary Figure 7 from Cooperativity of E-cadherin and Smad4 Loss to Promote Diffuse-Type Gastric Adenocarcinoma and Metastasis
Authors: Park Jun Won , Jang Seok Hoon , Park Dong Min , Lim Na Jung , Deng Chuxia , Kim Dae Yong , Green Jeffrey E. , Kim Hark Kyun
Published: April 2023

PDF - 106K, Activity of BMP-specific reporter (BRE-Luc) and TGF-beta reporter.
Supplementary Figure S1 from A Macrophage-Dominant PI3K Isoform Controls Hypoxia-Induced HIF1α and HIF2α Stability and Tumor Growth, Angiogenesis, and Metastasis
Authors: Joshi Shweta , Singh Alok R. , Zulcic Muamera , Durden Donald L.
Published: April 2023

Relative mRNA and protein expression level of PI-3 kinase isoforms in macrophages.
Supplementary Figure 3 from Cooperativity of E-cadherin and Smad4 Loss to Promote Diffuse-Type Gastric Adenocarcinoma and Metastasis
Authors: Park Jun Won , Jang Seok Hoon , Park Dong Min , Lim Na Jung , Deng Chuxia , Kim Dae Yong , Green Jeffrey E. , Kim Hark Kyun
Published: April 2023

PDF - 234K, Immunohistochemistry for the tissue origin.
Supplemental Figure Legend from Novel Bispecific Domain Antibody to LRP6 Inhibits Wnt and R-spondin Ligand-Induced Wnt Signaling and Tumor Growth
Authors: Jackson Heather , Granger David , Jones Gavin , Anderson Louisa , Friel Sarah , Rycroft Daniel , Fieles William , Tunstead James , Steward Michael , Wattam Trevor , Walker Adam , Griggs Jeremy , Al-Hajj Muhammad , Shelton Christopher
Published: April 2023

Supplemental Figure Legend 1
Supplementary Figures 1-9, Supplementary Tables 1-3 from Proteasome Subunits Differentially Control Myeloma Cell Viability and Proteasome Inhibitor Sensitivity
Authors: Shi Chang-Xin , Zhu Yuan Xiao , Bruins Laura A. , Bonolo de Campos Cecilia , Stewart William , Braggio Esteban , Stewart A. Keith
Published: April 2023

Sup.Fig.1. Expression of PSMB5 and PSMB6 from BTZ resistant MM cell lines JJN3, My5, and U266. Sup.Fig.2. Expression of PSMB5 detected by native and denaturing gels from cloned RPMI-8226 cells knocking out PSMB5. Sup.Fig.3. Selection of high efficiency SgRNAs targeting PSMB5. Sup.Fig.4. Restore BTZ sensitivity by knocking out PSMB5 from KMS11R cells. Sup.Fig.5. Cloned My5 cells without PSM5. Sup.Fig.6. Selection of high efficiency SgRNAs targeting PSMB6. Sup.Fig.7. Restore BTZ sensitivity by knocking out PSMB6 from KMS11R cells. Sup.Fig.8. Toxicity of knocking out PSMB6 from My5 cells. Sup.Fig.9. Deficiency of immunoproteasome PSMB8 and PSMB9 could not restore MM cell line sensitivity to BTZ treatment. Sup.Fig.10. Model of constitutive proteasome assembly. Sup. Table 1. List of 49 proteasome subunits. Sup. Table 2. SgRNAs used for targeting PSMB7 Sup. Table 3. SgRNAs used for targeting PSMB8 and PSMB9.
Supplemental Figure 4 from EMT Transition Alters Interstitial Fluid Flow–Induced Signaling in ERBB2-Positive Breast Cancer Cells
Authors: Tchafa Alimatou M. , Ta Mi , Reginato Mauricio J. , Shieh Adrian C.
Published: April 2023

Supplemental Figure 4: MCF10A and NeuN cells invade in groups of cells.
Supplemental Figure 3 from EMT Transition Alters Interstitial Fluid Flow–Induced Signaling in ERBB2-Positive Breast Cancer Cells
Authors: Tchafa Alimatou M. , Ta Mi , Reginato Mauricio J. , Shieh Adrian C.
Published: April 2023

Supplemental Figure 3: NeuN cells invade in response to IFF in the presence of exogenous CXCL12 (10 nM).
Supplemental Table 1: RT-PCR primers from The YAP-Interacting Phosphatase SHP2 Can Regulate Transcriptional Coactivity and Modulate Sensitivity to Chemotherapy in Cholangiocarcinoma
Authors: Buckarma EeeLN H. , Werneburg Nathan W. , Conboy Caitlin B. , Kabashima Ayano , O'Brien Daniel R. , Wang Chen , Rizvi Sumera , Smoot Rory L.
Published: April 2023

RT-PCR primers
Supplemental Figure Legends from The YAP-Interacting Phosphatase SHP2 Can Regulate Transcriptional Coactivity and Modulate Sensitivity to Chemotherapy in Cholangiocarcinoma
Authors: Buckarma EeeLN H. , Werneburg Nathan W. , Conboy Caitlin B. , Kabashima Ayano , O'Brien Daniel R. , Wang Chen , Rizvi Sumera , Smoot Rory L.
Published: April 2023

Supplemental Figure Legends
Table S1 from c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase–Activated Leukemias
Authors: Muvarak Nidal , Kelley Shannon , Robert Carine , Baer Maria R. , Perrotti Danilo , Gambacorti-Passerini Carlo , Civin Curt , Scheibner Kara , Rassool Feyruz V.
Published: April 2023

Table S1. Clinical, Molecular and Karyotypic Features of AML Patients
Supplemental Tables 1 and 2 from BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer
Authors: Asangani Irfan A. , Wilder-Romans Kari , Dommeti Vijaya L. , Krishnamurthy Pranathi M. , Apel Ingrid J. , Escara-Wilke June , Plymate Stephen R. , Navone Nora M. , Wang Shaomeng , Feng Felix Y. , Chinnaiyan Arul M.
Published: April 2023

Antibodies and PCR Primers
Supplemental Figure 5 from Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer
Authors: Vickman Renee E. , Crist Scott A. , Kerian Kevin , Eberlin Livia , Cooks R. Graham , Burcham Grant N. , Buhman Kimberly K. , Hu Chang-Deng , Mesecar Andrew D. , Cheng Liang , Ratliff Timothy L.
Published: April 2023

SULT2B1b KD in C4-2 cells induces cell death.
Supplemental Figure Legends from BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer
Authors: Asangani Irfan A. , Wilder-Romans Kari , Dommeti Vijaya L. , Krishnamurthy Pranathi M. , Apel Ingrid J. , Escara-Wilke June , Plymate Stephen R. , Navone Nora M. , Wang Shaomeng , Feng Felix Y. , Chinnaiyan Arul M.
Published: April 2023

Supplemental Figure Legends
Supplemental Figure 4 from Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer
Authors: Vickman Renee E. , Crist Scott A. , Kerian Kevin , Eberlin Livia , Cooks R. Graham , Burcham Grant N. , Buhman Kimberly K. , Hu Chang-Deng , Mesecar Andrew D. , Cheng Liang , Ratliff Timothy L.
Published: April 2023

shRNA KD of SULT2B1b expression yields similar results to siRNA KD.
Supplemental Figure 4 from BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer
Authors: Asangani Irfan A. , Wilder-Romans Kari , Dommeti Vijaya L. , Krishnamurthy Pranathi M. , Apel Ingrid J. , Escara-Wilke June , Plymate Stephen R. , Navone Nora M. , Wang Shaomeng , Feng Felix Y. , Chinnaiyan Arul M.
Published: April 2023

AR- and ERG-positive PDX model displays sensitivity to JQ1.
Supplemental Figure 3 from Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer
Authors: Vickman Renee E. , Crist Scott A. , Kerian Kevin , Eberlin Livia , Cooks R. Graham , Burcham Grant N. , Buhman Kimberly K. , Hu Chang-Deng , Mesecar Andrew D. , Cheng Liang , Ratliff Timothy L.
Published: April 2023

SULT2B1b KD reduces RWPE-1 cell viability.
Supplemental Figure 1 from Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer
Authors: Vickman Renee E. , Crist Scott A. , Kerian Kevin , Eberlin Livia , Cooks R. Graham , Burcham Grant N. , Buhman Kimberly K. , Hu Chang-Deng , Mesecar Andrew D. , Cheng Liang , Ratliff Timothy L.
Published: April 2023

SULT2B1b expression and CS accumulation in human prostate specimens.
Supplementary Table 1 from COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation
Authors: Majumder Mousumi , Landman Erin , Liu Ling , Hess David , Lala Peeyush K.
Published: April 2023

Supplementary Table 1. List of miRNAs significantly down or up regulated in MCF7-COX-2 compared to MCF7-Mock cell line
Supplementary materials from NME2 Is a Master Suppressor of Apoptosis in Gastric Cancer Cells via Transcriptional Regulation of miR-100 and Other Survival Factors
Authors: Gong Yi , Yang Geng , Wang Qizhi , Wang Yumeng , Zhang Xiaobo
Published: April 2023

Supplementary materials
Supplementary Figure 2 from COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation
Authors: Majumder Mousumi , Landman Erin , Liu Ling , Hess David , Lala Peeyush K.
Published: April 2023

Supplementary Figure 2. Representative images for migrant MCF7 and SKBR3 miR526b over expressed cells