bluuebunny/crossref_metadata_2025 huggingface dataset:
Is anemia a clinical marker of NSAIDs-induced upper gastrointestinal lesions in patients with spondyloarthritis?
Authors: Safarova K. N. , Dorogoykina K. D. , Rebrov A. P.
Published: July 2019

Background: Anemia is a frequent comorbid conditions in patients with spondyloarthritis (SpA). Its development is associated with the activity of the underlying disorder, and in some cases can be a complication of medical treatment. Investigation into the particulars of the anemia, its prevalence in SpA patients is of considerable interest due to the long-term inflammatory process, on the one hand, and high frequency of non-steroidal anti-inflammatory drugs (NSAIDs) usage, on the other.

Aim: To assess the incidence of NSAID-induced lesions of upper gastrointestinal tract in patients with SpA and anemia.

Materials and methods: This cross-sectional observational study included 107 patients with proven SpA (mean age, 44 [36; 53] years; SpA duration, 16 [9; 21] years; men, 61.9%) who were treated in the Department of Rheumatology, Saratov Regional Clinical Hospital, from 2017 to 2018. We assessed their blood cell counts, C-reactive protein levels, iron kinetic parameters (serum iron, transferrin, ferritin, transferrin saturation). Anemia was diagnosed according to the World Health Organization criteria. Two groups were formed depending on the presence of absolute iron deficiency: group 1, 13 patients with anemia of chronic disease (ACD), group 2, 3 patients with iron deficiency anemia (IDA) and 26 patients with ACD + IDA. Esophagogastroduodenoscopy (EGDS) was performed to assess mucous membranes of the upper gastrointestinal tract in patients with anemia.

Results: Anemia was found in 42 (39.3%) patients, 38 (90.5%) of them had mild anemia. The increase in the activity of the underlying disorder judged by changes in the laboratory markers of systemic inflammation (erythrocyte sedimentation rate and C-reactive protein levels) significantly correlated with a decrease in hemoglobin concentration (r = -0.5715 and r = -0.3498 respectively, p<0.05). At EGDS, NSAIDs-induced erosions in the esophagus and/or stomach were found detected in 1 (7.7%) patient of the group 1 and in 1 (3.4%) patient of the group 2. A past episode of NSAIDs-induced erosions in the stomach and duodenum was noted in 4 (13.8%) patients of the group 2, whereas at the time of the study no mucous membranes defects were found at EGDS.

Conclusion: Anemia was found in more than one third of SpA patients, with 29 of them (69%) having laboratory signs of iron deficiency, but only 1 (3.4%) patient had NSAIDs-induced gastropathy confirmed at EGDS. NSAIDs-associated enteropathy could be the cause of iron deficiency in these patients that would require additional patient examination. The development of iron deficiency can be pathophysiologically associated to prolonged inhibition of alimentary iron absorption against the background of persistent systemic inflammation and depletion of the iron pool in the absence of gastrointestinal blood losses.
Assessment of the Socrative platform as an interactive and didactic tool in the performance improvement of STEM university students
Authors: Gómez-Espina Roberto , Rodríguez-Oroz Delia , Chávez Manuel , Saavedra Cristian , Bravo María Jesús
Published: July 2019

This paper collects and analyzes students' academic results related to the change in teaching methodologies used in different subjects of different science and engineering university courses between 2013 and 2016. This change means introducing active methodologies such as gamification and ICT instead of a traditional methodology. With this purpose the use of Socrative, a platform that has been designed for the educational field, was introduced during said period. Interaction with the Socrative platform took place in well prepared classrooms with computers and internet connections, including the use of personal mobile devices (laptops, smartphones and tablets) according to the BYOD methodology. The active methodology implemented allowed students to improve their academic results while learning and improving their passing rates.
VIRTOPSY AFTER FATAL INJURY BY LANDING GEAR OF AN AIRCRAFT BOEING 737
Authors: Klevno V. A. , Tarkhnishvili G. S. , Spitsyna L. I. , Mirzonov V. A. , Balanyuk E. A.
Published: July 2019

The article presents a rare case of virtopsy of a mortally injured person on the runway by the landing gear of the overclocking Boeing 737 aircraft. A case from the expert practice of the Khimki forensic medical department with preliminary pre-sectional MDCT examination of the corpse (virtual autopsy) and subsequent MDCT anatomical comparison of the results.
CLINICAL AND ANATOMICAL COMPARISONS IN ASSESSING THE QUALITY OF MEDICAL CARE
Authors: Kakturskiy L. V. , Zayratyants O. V.
Published: July 2019

Purpose of research: To study methodological, organizational and normative problems of comparison of final clinical and pathological-anatomical diagnoses in the Russian Federation on the basis of a review of domestic and foreign publications.Abstract: Clinical and anatomical comparisons remain the most important function of quality control of medical and diagnostic work. Cases of divergence of diagnoses should be the subject of professional discussion in the medical community with the adoption of appropriate administrative measures to address deficiencies in the provision of medical care. Currently, there is no adequate regulatory regulation of the issue of comparison of clinical and pathological-anatomical diagnoses. This gives rise to many problems, including the subjectivism of the pathologist in the interpretation of the actions of the clinician, the permanent threat of criminal liability of medical workers for misdiagnosis. Penalties for discrepancies in diagnoses imposed by the Сompulsory Health Insurance Fund lead to an artificial underestimation of the divergence of diagnoses in medical organizations and to incorrect statistical accounting. The underestimation of the role of comorbid diseases and the lack of clear norms of their use in the diagnosis create difficulties in the correct assessment of the disease tanatogenesis, limits the analysis of morbidity and mortality for multiple reasons and entails the loss of some of the available information.
Plantas medicinales: aspectos básicos de una alternativa terapéutica emergente para el control de las infecciones oculares bacterianas
Authors: Velasco García Wendy Johanna , Pabón Ludy C. , Hernández-Rodríguez Patricia
Published: July 2019

Las bacterias son los patógenos principales relacionados con infecciones que afectan las estruc¬turas del ojo de forma intra- o extraocular; el género Staphylococcus es el grupo más prevalente asociado con este tipo de infección. Para el control de las infecciones oculares se utilizan an¬tibióticos como oxacilina y meticilina, que en muchos casos llevan a la resistencia bacteriana. Además, el alto costo de los medicamentos, que en Colombia alcanzan cifras tres o cuatro veces mayores que en otros países, se constituyen en desventajas para su uso. Lo anterior ha llevado a estudiar la actividad antimicrobiana de las plantas frente a los microorganismos asociados a las infecciones oculares bacterianas. El propósito de este artículo de revisión es conocer los bene¬ficios potenciales de las plantas o sus productos para el control de estas infecciones como una alternativa para su tratamiento.
El origen de la mujer: un relato de la cosmogonía huichol (wixárika)
Authors: Ramos Stefanie , Félix Norma
Published: July 2019

Este artículo presenta un fragmento perteneciente a la cosmogonía huichol (wixárika), que cuenta el origen de las mujeres. La narración forma parte de una de las historias sobre el nacimiento de los hui- choles y su relación con un diluvio ocasionado por Nakawé, deidad ancestral. La presentación del texto in- cluye la transcripción en el alfabeto del huichol, segmentación morfológica, glosado y traducción al español. Además se proporciona información etnográfica y lingüística sobre la lengua. El relato muestra distintos aspectos de la cosmogonía, sistema de organización del núcleo familiar de los huicholes y su relación con la comunidad de Tateikie (San Andrés Cohamiata, Jalisco). Su contexto, asimismo, refleja la inclusión de elementos cristianos en la simbología de la tradición huichol. El fragmento, finalmente, permite analizar la estructura gramatical del huichol, la cual cuenta con pocos estudios lingüísticos.
Direitos humanos e justiça restaurativa nas escolas
Authors: Pereira Ana Carolina Reis , Guimarães Áurea Marias
Published: July 2019

Partindo do pressuposto que a relação entre os direitos humanos e a mediação de conflitos pela via das práticas restaurativas possui um potencial emancipador ainda não devidamente realizado, o que enseja não só uma reflexão sobre o problema da efetivação da democracia e dos direitos no Brasil, mas também das resistências e indícios, ainda que tímidos, de novas possibilidades democráticas, o presente artigo tem por objetivo compreender, a partir da narrativa dos professores egressos da formação “Cultura Restaurativa e suas Práticas”, o lugar que os direitos humanos e a justiça tiveram em suas trajetórias e como negociaram a introdução dos seus princípios em suas práticas. Com este intuito, adotamos o referencial teórico-metodológico da história oral de vida, por considerarmos que esta proposta nos permite captar experiências que significam por suas singularidades e, ao mesmo tempo, pela inscrição delas em um contexto social mais amplo. Autores como Arendt, Benevides, Holanda, Duschatzky, nos ajudaram a problematizar a situação dos direitos humanos, da justiça restaurativa e da democracia entre nós. Apesar de identificarmos nas expressões dos professores que a inclusão da justiça restaurativa nas escolas foi benéfica por introduzir o diálogo com os alunos, também percebemos que suas narrativas são desprovidas de compromissos mais consistentes com os seus pressupostos. Acreditamos, entretanto, que o reposicionamento da justiça restaurativa em âmbito educacional poderia tornar possível não apenas a prevenção da violência no interior das unidades escolares, mas poderia ensejar modos de conviver mais potentes, abertos ao diálogo, e dispostos à construção de relacionamentos democráticos.
A pele bordada como traje de cena
Authors: Gil Maria Celina , Viana Fausto
Published: July 2019

Este artigo investiga a possibilidade de compreender a pele do ator como traje de cena a partir da perspectiva do bordado. Sem se propor a chegar a uma conclusão definitiva à questão, o artigo se apoia em duas noções: a de que o ator e a personagem são pessoas diferentes; e a ideia de que a nudez não representa o grau zero do traje de cena. Duas performances envolvendo modificação corporal com bordado exemplificam essas ideias, com suporte teórico em Pires, Viana e Pavis.
Mulher, velhice e solidão
Authors: Dias Marly de Jesus Sá , Serra Jacira
Published: July 2019

Considerações sobre a velhice feminina a partir de revisão bibliográfica, com o propósito de apreender o significado da elevação de mulheres nesta população no Brasil, bem como dos elementos que tem concorrido para a solidão delas nesta fase da vida. Situação agravada nos grandes centros urbanos, em que as relações familiares e sociais se complexificam e favorecem a instauração de vazios intensos e afastamentos das pessoas com mais idade do convívio social. Conclui-se que a velhice é resultante de um conjunto de fatores, com repercussões e demandas por políticas públicas que precisam considerar as desigualdades de gênero e a preponderância das mulheres idosas em suas formulações e implementações.
Serviço Social e tecnologias de saúde
Authors: Mangini Fernanda Nunes da Rosa , Kocourek Sheila , Silveira Laureana Vargas
Published: July 2019

O presente artigo procura analisar a vinculação das tecnologias de saúde com os distintos projetos médico assistenciais e sanitaristas, bem como, identificar possíveis contribuições do Serviço Social à democratização e garantia do direito à saúde, tomando como base os estudos sociais da tecnologia. Trata-se de um estudo teórico-bibliográfico, que parte do pressuposto de que a tecnologia constitui-se numa das principais fontes de poder da atualidade, sendo isenta de neutralidade. Este trabalho está estruturado em três eixos: no primeiro eixo discute o conceito de tecnologia; no segundo, aproxima o debate das relações entre tecnologia, política e democracia, buscando fundamentar teoricamente a prática profissional do assistente social, visto que a mesma é mediada pela tecnologia na política pública de saúde; e, no terceiro eixo, discorre sobre os dois principais projetos sanitaristas em disputa e suas relações com a tecnologia, mostrando que cada projeto prioriza diferentes tipos de tecnologias, que devem ser construídas e socializadas de modos distintos. Apoiada no modelo médico hegemônico de saúde, a tecnologia tende a se apresentar de maneira hierárquica e autoritária, focada em procedimentos. Já respaldada pelo modelo de assistência à saúde defendido pelo Movimento de Reforma Sanitária, tende a ser construída de maneira democrática, participativa, voltada sua centralidade para os usuários. Nessa direção, são tecidas considerações para a construção contra hegemônica das tecnologias por parte dos usuários e profissionais de Serviço Social com vistas ao enfrentamento das relações assimétricas e autoritárias, distanciadas da perspectiva de garantia de direitos e da construção do trabalho em equipe no SUS.
Public policy for the sustainable industries in Semarang Regency
Authors: Julana Ardhiansyah Noer , Sasongko Gatot
Published: July 2019

The spatial planning policies had become the mediators for political, social, economic, and environmental relations. This study aims to describe the implementation of public policy from the perspective of Dye theory about a spatial planning for industries in Semarang Regency. The primary data used in this study was from nine informants of nine companies which applied for a location permission license for industrial activities. The secondary data was from the Semarang Public Works Office. The study shows that there were nine investment activity plans for industries in Semarang Regency. Initially, the nine applications were not granted permission from the relevant agencies because they were not in accordance with the provisions of spatial planning. However, after being considered by the government in terms of public policy, the nine companies obtained location permission licenses to utilize the land under certain conditions. Thus, the public policy is essentially designed by the government to guarantee and fulfill the needs of the community to conduct investment activities such as industry. The spatial planning policies had become the mediators for political, social, economic, and environmental relations. Thus, harmonization of political, social, economic and environmental aspects would create sustainable development.
An Efficient Ic On chip Test Framework To Embed Tsv Testing In Memory Bist Using Dynamic Technique
Authors:   ME-VLSI Design, ,Sri Ramanujar Engineering,College, Vandalur, Kolappakkam,Chennai, Ms G.Vithya , Mr P. Krishnakumar ,   Assistant Professor (OG), ,Dept of ECE, Sri Ramanujar Engineering College,Vandalur,Kolappakkam, Chennai
Published: July 2019

An end-to-end design of a built-in self-test (BIST) infrastructure for 3D-stacked ICs that facilitate the use of BIST at multiple stages of 3D integration. The proposed BIST design is distributed, reusable, and reconfigurable, hence it is attractive for both pre-bond and post-bond testing. We also provide support for translating a static BIST schedule into a set of BIST control instructions. The BIST design is validated using detailed simulations of the various operating modes. It results on synthetic stacks assess the impact of inserting BIST in these designs in terms of area, timing, and power overhead. Results show that the overhead due to BIST is negligible. It also formulate a test-scheduling problem that aims at minimizing test time under BIST-resource and power constraints, and use two algorithms based on bin packing for solving the problem.
Penggunaan Metode SIIT (Stateless IP/ICMP Translation) Dalam Migrasi IPv4 ke IPv6
Authors: Nugroho Kukuh
Published: July 2019

Pengguna Internet yang semakin bertambah mengakibatkan meningkatnya kebutuhan penggunaan alamat IP. Saat  ini alokasi alamat IPv4 versi public sudah tidak bisa menampung kebutuhan pengguna Internet. IP versi 6 (IPv6) sebagai IP versi terbaru yang memiliki daya tampung yang lebih banyak dibandingkan dengan IP versi 4 (IPv4) dapat dijadikan sebagai solusi terhadap masalah berkurangnya atau menipisnya alokasi alamat IPv4 versi public. Perangkat yang sudah terpasang dalam jaringan dan menggunakan alamat IPv4 tidak secara langsung digantikan dengan alamat IPv6. Pada praktiknya, perangkat yang menggunakan IPv6 akan disandingkan dengan perangkat yang sudah menggunakan IPv4. Konsep penggunaan konsep pengalamatan yang berbeda akan menimbulkan masalah dari sisi konektifitas antar perangkat. Oleh karena itu diperlukan sebuah solusi agar jaringan yang sudah menggunakan IPv4 dapat terhubung dengan perangkat yang menggunakan IPv6. Pada penelitian ini akan digunakan salah satu metode dalam menghubungkan antara jaringan IPv4 dan IPv6 yaitu SIIT (Stateless IP/ICMP Translation). Parameter performansi yang dianalisa adalah throughput, packet loss dan delay. Konsep jaringan yang digunakan adalah client-server, dimana pada sisi server akan diaktifkan dua layanan untuk diuji yaitu transfer file dan video streaming.
Design of Three Phase Solid State Transformer Deployed within Multi-Stage Power Switching Converters
Authors: Tahir Umair , Abbas Ghulam , Glavan Dan Ovidiu , Balas Valentina E. , Farooq Umar , Balas Marius M. , Raza Ali , Asad Muhammad Usman , Gu Jason
Published: July 2019

This paper presents a symmetrical topology for the design of solid-state transformer, made up of power switching converters, to replace conventional bulky transformers. The proposed circuitry not only reduces the overall size but also provides power flow control with the ability to be interfaced with renewable energy resources (RESs) to fulfill the future grid requirements at consumer end. Solid state transformer provides bidirectional power flow with variable voltage and frequency operation and has the ability to maintain unity power factor, and current total harmonic distortion (THD) for any type of load within defined limits of IEEE standard. Solid State Transformer offers much smaller size as compared to that of the conventional iron core transformer. MATLAB/Simulink platform is adopted to test the validity of the proposed circuit for different scenarios by providing the simulation results evaluated at 25 kHz switching frequency.
Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer
Authors: Perilli Lisa , Tessarollo Sofia , Albertoni Laura , Curtarello Matteo , Pastò Anna , Brunetti Efrem , Fassan Matteo , Rugge Massimo , Indraccolo Stefano , Amadori Alberto , Bortoluzzi Stefania , Zanovello Paola
Published: July 2019

Background: miR-182-5p (miR-182) is an oncogenic microRNA (miRNA) in different tumor types and one of the most up-regulated miRNA in colorectal cancer (CRC). Although this microRNA is expressed already in early steps of tumor development, its role in driving tumorigenesis is unclear. Methods: The effects of miR-182 silencing on transcriptomic profile were investigated using two CRC cell lines characterized by different in vivo biological behavior, the MICOL-14h-tert cell line (dormant upon transfer into immunodeficient hosts) and its tumorigenic variant, MICOL-14tum. Apoptosis was studied by annexin/PI staining and cleaved Caspase-3/PARP analysis. The effect of miR-182 silencing on the tumorigenic potential was addressed in a xenogeneic model of MICOL-14tum transplant.Results: Endogenous miR-182 expression was higher in MICOL-14tum than in MICOL-14h-tert cells. Interestingly, miR-182 silencing had a strong impact on gene expression profile, and the positive regulation of apoptotic process was one of the most affected pathways. Accordingly, annexin/PI staining and caspase-3/PARP activation demonstrated that miR-182 treatment significantly increased apoptosis, with a prominent effect in MICOL-14tum cells. Moreover, a significant modulation of cell cycle profile was exerted by anti-miR-182 treatment only in MICOL-14tum cells, where a significant increase in the fraction of cells in G0/G1 phases was observed. Accordingly, a significant growth reduction and a less aggressive histological aspect were observed in tumor masses generated by in vivo transfer of anti-miR-182-treated MICOL-14tum cells into immunodeficient hosts. Conclusions: Altogether, these data indicate that increased miR-182 expression may promote cell proliferation, suppress the apoptotic pathway and ultimately confer aggressive traits on CRC cells.
Sero-prevalence of HCV among HIV infected adult patients attending Comprehensive Care Center at Kenyatta National Hospital
Authors: Ukio Kusirye Boniphace , Anzala Omu , Mureithi Marianne W.
Published: July 2019

Objective

The objective of the study was to assess the prevalence of Hepatitis C virus infection and associated risk factors amongst HIV/AIDS adult patients in a sub-Saharan setting.

Results

Two hundred and forty (240) HIV/AIDS patients were recruited from Comprehensive Care Center at KNH.A total of 21 days were spent in the recruitment. The mean age of the participants was 41 years with a standard deviation of 11. The ages ranged between 18 years and 76 years. Majority of the participants were between 30 and 50 years of age. 70% of recruited participants were residing in Nairobi, 16% in Kiambu, 4% in Machakos, 3% in Kajiado and 7% in other counties. 72% of all recruited participants were females, whereas males accounted for 28%. The Prevalence of HCV among Adult HIV/AIDS was 0%. Among risk factors assessed, sexually transmitted infections accounted for 20.4% of all risk factors. None of the participants had a history of intravenous drug use.
Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts
Authors: AlSudais Hamood , Wiper-Bergeron Nadine
Published: July 2019

Objective
CCAAT/Enhancer Binding proteins (C/EBPs) are transcription factors involved in the regulation of a variety of cellular processes. We used the Abcam Recombinant Anti-C/EBP beta antibody (E299) to detect C/EBPβ expression during myogenesis. Though the antibody is monoclonal, and the immunogen used is highly specific to C/EBPβ, we identified an intense band at 23 kDa on western blot that did not correspond to any of the known isoforms of C/EBPβ, or family members predicted to cross-react. Absent in myoblast cells overexpressing C/EBPβ, the band was present when C/EBPβ was knocked down, confirming specificity for a protein other than C/EBPβ. The objective of this work was to identify the contaminating reactivity.
Results
We performed immunoprecipitation followed by mass spectrometry to identified myosin light chain 4 (MYL4) as the unknown band, suggesting that the Abcam monoclonal antibody directed against C/EBPβ is not pure, but contains a contaminating antibody against MYL4. Caution should be used when working in cells lines that express MYL4 to not confound the detection of MYL4 with that of the C/EBPβ LIP isoform.
The predictive value of diaphragm ultrasound for weaning outcomes in critically ill children
Authors: Xue Yang , Zhang Zhen , Sheng Chu-Qiao , Li Yu-Mei , Jia Fei-Yong
Published: July 2019

Background: Multiple studies have shown that diaphragmatic ultrasound can better predict the outcome of weaning in adults. However, there are few studies focusing on children, leading to a lack of sufficient clinical evidence for the application of diaphragmatic ultrasound in children. The purpose of this study was to investigate the predictive value of diaphragm ultrasound for weaning outcomes in critically ill children.
Methods: Study included 50 cases whose mechanical ventilation(MV) time > 48 h, and all eligibles were divided into either the weaning success group (n = 39) or the weaning failure group (n = 11). Diaphragm thickness and diaphragmatic excursion (DE) were measured in the zone of apposition. The maximum inspiratory pressure (PImax) was also recorded.
Results: The ventilatory treatment time (P = 0.002) and length of PICU stay (P = 0.013) in the weaning failure group was longer than the success group. Cut-off values of diaphragmatic measures associated with successful weaning were ≥ 21% for DTF with a sensitivity of 0.82, and a specificity of 0.81, whereas it was ≥ 8.40 mm for DE with a sensitivity of 0.62, and a specificity of 0.91. The linear correlation analysis showed that DTF had no significant correlation with PImax in children (P = 0.31).
Conclusions: Diaphragm ultrasound has great value in predicting the weaning outcome of critically ill children. DTF and DE presented better performance than other diaphragmatic parameters. However, PImax has limited value in terms of reflecting the inspiratory muscle function of children with MV.
Trial Registration: The trial ‘Early rehabilitation intervention for critically ill children’ has been registered at http://www.chictr.org.cn/showproj.aspx?proj=23132. Registration number: ChiCTR1800020196.
Key words: Paediatric; mechanical ventilation; diaphragm; ultrasound; weaning; PImax
Metagenomic next-generation sequencing for mixed pulmonary infection diagnosis
Authors: Wang Jiahui , Han Yelei , Zhou Yang , Feng Jing
Published: July 2019

Background. Metagenomic next-generation sequencing (mNGS) is emerging as a promising technique for pathogens detection. However, reports on the application of mNGS in mixed pulmonary infection remain scarce.
Methods. From July 2018 to March 2019, 55 cases were enrolled in this retrospective analysis. Cases were classified into mixed pulmonary infection (36 [65.5%]) and non-mixed pulmonary infection (19 [34.5%]) according to primary diagnoses. The performances of mNGS and conventional test on mixed pulmonary infection diagnosis and pathogen identification were compared.
Results.The sensitivity of mNGS in mixed pulmonary infection diagnose was much higher than that of conventional test (97.2％ vs 13.9％;P<0.01) , but the specificity was the opposite (63.2％ vs 94.7％;P=0.07) . The positive predictive value of mNGS was 83.3% (95% CI: 68.0-92.5%) , and the negative predictive value was 92.3% (95% CI: 62.1-99.6%) . A total of 5 (9.1%) cases were identified as mixed pulmonary infection by both conventional tests and mNGS, however, the pathogens identification results were consistent between these two methods in only 1(1.8%) case. In summary, the pathogens detected by mNGS in 3 (5.5%) cases were consistent with those by conventional test, and only 1(1.8%) case was mixed pulmonary infection. According to our data, mNGS had a broader spectrum for pathogen detection than conventional tests. In particular, application of mNGS improved the diagnosis of pulmonary fungal infections. Within the 55 cases, mNGS detected and identified fungi in 31 (56.4%) cases, of which only 10 (18.2%) cases were positive for the same fungi by conventional test. The most common pathogen detected was Human cytomegalovirus in our study, which was identified in 19(34.5%) cases of mixed pulmonary infection. Human cytomegalovirus and Pneumocystis jirovecii, which were detected in 7(12.7%) cases, were the most common co-pathogens in the group of mixed pulmonary infection.
Conclusions. mNGS is a promising technique to detect co-pathogens in mixed pulmonary infection, with potential benefits in speed and sensitivity.
ANALYSIS OF BUSINESS - IS/IT STRATEGY : AN EMPIRICAL STUDY OF STARTUP DIGITAL COMPANY
Authors: Nastiti Putri
Published: July 2019

Not only as a communication support, technological developments also influence the shifting lifestyle of urban communities. This is the main reason of innovators who want to create solutions to various problems through technological innovation. This is in line with the development of startup companies in the field of technology. One of the startup company that become part of ADITIF will be the object of this research. The results of this study are to know the internal and external conditions of the company, both in area of business and IS / IT and then be evaluated and proposed strategic recommendations that are in accordance with the culture of the startup company. Some of the strategic proposals generated from this study include the IS strategy in the form of a proposed administrative application portfolio to support the company's business processes, the IT strategy in the form of the maximum use of cloud computing, and the IS / IT management strategy in the form of a list of proposed business activities alignment strategy
Out of time ordered effective dynamics of a quartic oscillator
Authors: Chakrabarty Bidisha , Chaudhuri Soumyadeep
Published: July 2019

We study the dynamics of a quantum Brownian particle weakly coupled
to a thermal bath. Working in the Schwinger-Keldysh formalism, we
develop an effective action of the particle up to quartic terms. We
demonstrate that this quartic effective theory is dual to a stochastic
dynamics governed by a non-linear Langevin equation. The
Schwinger-Keldysh effective theory, or the equivalent non-linear
Langevin dynamics, is insufficient to determine the out of time order
correlators (OTOCs) of the particle. To overcome this limitation, we
construct an extended effective action in a generalised
Schwinger-Keldysh framework. We determine the additional quartic
couplings in this OTO effective action and show their dependence on the
bath’s 4-point OTOCs. We analyse the constraints imposed on the OTO
effective theory by microscopic reversibility and thermality of the
bath. We show that these constraints lead to a generalised
fluctuation-dissipation relation between the non-Gaussianity in the
distribution of the thermal noise experienced by the particle and the
thermal jitter in its damping coefficient. The quartic effective theory
developed in this work provides extension of several results previously
obtained for the cubic OTO dynamics of a Brownian particle.
Desde el texto hacia la imagen. Avatares del paradigma imagético y de la cultura visual
Authors: Campos Winter Hugo
Published: July 2019

En el siguiente texto se argumenta que actualmente se estaría dando un giro en la comunidad científica desde el paradigma textual hacia un paradigma imagético. En primer lugar se explica, desde una perspectiva histórica en epistemología, el modo en que se despliega dicho cambio paradigmático. A continuación, y con la óptica de la epistemología política, se realiza una crítica a los efectos de la difusión de la imagen técnica, núcleo del paradigma imagético, en la sociedad de la cultura visual. Se concluye argumentando la necesidad de aprender a leer críticamente las imágenes, tomando de modelo al cine como medio donde se configura la síntesis de un conocimiento imagético-textual, así como un lugar donde se crea y recrea una comunidad de espectadores críticos.
Alabaos: El papel del cuidado en la sanación del dolor. Experiencia desde victimas sobrevivientes de violencia sexual en el contexto colombiano.
Authors: Cruz Castillo Alba Lucía , Calderón Alejandra , Flórez Sonia , Cardoso Laura
Published: July 2019

El artículo tiene como objetivo visibilizar las estrategias de agenciamiento político de mujeres negras afrocolombianas integrantes de la Asociación de Mujeres Afro por la Paz (Afromupaz) a partir de los procesos e iniciativas colectivas que han elaborado para afrontar los daños ocasionadas por el conflicto armado en Colombia; además, busca indagar acerca de su posición política como víctimas sobrevivientes y las acciones colectivas para su reconocimiento como tal, así como los principios éticos que emergen desde sus prácticas autónomas para la reparación como comunidad negra. La ponencia es resultado de un proceso de investigación e intervención abordado desde el enfoque narrativo el cual permite un acercamiento a las experiencias de las mujeres integrantes de la asociación y el sentido que ellas atribuyen a éstas vivencias colectivas para reconocer la importancia de una plataforma política y su participación durante el proceso. Adicionalmente la ponencia ilustra la manera en que las mujeres se han posicionado como sobrevivientes logrando un apoyo y un afrontamiento activo de la situación traumática desde el uso de prácticas ancestrales chocoanas (negras), implementado bailes, música y tradiciones, en dicho proceso de afrontamiento han tenido un lugar relevante el patrimonio cultural inmaterial y las prácticas sociales de mujeres negras en torno a la empatía, el cuidado y la sociabilización política de la solidaridad y la confianza transmitidas a través del cuidado como potencializador de ciudadanía. En este sentido la ponencia intenta debatir desde esta experiencia la hegemonización de la ciudadanía y visibilizar el cuidado en la agencia de ciudadanías diferenciales y la forma en que estas se activan en torno a la resolución del dolor y la reparación colectiva en contextos de conflicto armado como en el caso colombiano.
BREVES APONTAMENTOS SOBRE O PAPEL DO DIREITO DE RESISTÃŠNCIA NA FORMAÃ‡ÃƒO DOS ESTADOS DEMOCRÃTICOS DE DIREITO
Authors: Lamas LÃ­via Paula de Almeida
Published: July 2019

O presente ensaio se propÃµe a fazer uma anÃ¡lise do papel exercido pelo direito de resistÃªncia na formaÃ§Ã£o dos Estados DemocrÃ¡ticos de Direito, de forma a demonstrar que eles funcionam como uma garantia de autodefesa da sociedade frente aos abusos contra os direitos fundamentais do ser humano. O direito de resistÃªncia Ã© considerado a partir do sÃ©culo XV, pois somente a partir dessa data ele pode ser visto como uma InstituiÃ§Ã£o. Ã‰ tambÃ©m nesse perÃ­odo que se inicia o processo em que os direitos humanos fundamentais comeÃ§am a ser inseridos em todos os Ã¢mbitos da vida civil e assumem um papel essencial na proteÃ§Ã£o do indivÃ­duo enquanto sujeito de direitos.
A DISCUSSÃƒO PROCESSUAL DA ORDEM PÃšBLICA COMO FUNDAMENTO DA PRISÃƒO PREVENTIVA NO BRASIL
Authors: Lopes Marcus VinÃ­cius Pimenta , Ribeiro Rafhael Lima
Published: July 2019

Este artigo discorrerÃ¡ sobre a â€œordem pÃºblicaâ€ como fundamento da decretaÃ§Ã£o da prisÃ£o preventiva, para tanto verificarÃ¡ que essa espÃ©cie de prisÃ£o provisÃ³ria deveria obrigatoriamente expressar a cautelaridade processual penal, uma vez que o seu fito Ã© garantir a eficÃ¡cia do processo principal. De modo que, inexistindo sentenÃ§a penal com o trÃ¢nsito em julgado, deveriam ser garantidos os direitos fundamentais do acusado, principalmente o Estado de InocÃªncia, para que nÃ£o haja um processo penal de autor, em detrimento de uma persecuÃ§Ã£o penal democrÃ¡tica e garantista.
MATERIALIZAÃ‡ÃƒO DO PROJETO Ã‰TICO POLÃTICO PROFISSIONAL E AS CONDIÃ‡Ã•ES DE TRABALHO DE ASSISTENTES SOCIAIS NO INTERIOR DE MINAS GERAIS
Authors: Lopes NoÃªmia de FÃ¡tima Silva , Cortes Ana Paula , Segal Daniele Alves , Andrade Ivani de , Silva Janaina de Oliveira , Afonso JÃ©ssica da Silva , Moraes Leslie de , Abreu LornÃ­dia da Silva , Rodrigues VerÃ´nica da Mata Huebra
Published: July 2019

O objetivo deste estudo foi analisar de que forma o Projeto Ã‰tico PolÃ­tico do ServiÃ§o Social tem sido materializado por assistentes sociais na regiÃ£o do municÃ­pio de ManhuaÃ§u, MG. A prÃ¡tica do ServiÃ§o Social Ã© uma atividade laboral exercida por profissional habilitado, capaz de trabalhar o conjunto de expressÃµes das desigualdades sociais geradas na sociedade capitalista. Os instrumentos de trabalho do ServiÃ§o Social estÃ£o diretamente associados Ã  formaÃ§Ã£o teÃ³rica, tÃ©cnico-operacional e Ã©tico-polÃ­tica. Sua finalidade social estÃ¡ voltada para a intervenÃ§Ã£o naperspectiva de democratizaÃ§Ã£o, autonomia dos sujeitos, acesso aos direitos, e Ã  clareza do projeto Ã©tico-polÃ­tico - fundamental para o fortalecimento desta categoria profissional e da classe trabalhadora. Este estudo de carÃ¡ter exploratÃ³rio utilizou-se da pesquisa qualitativa fundamentada no mÃ©todo crÃ­tico dialÃ©tico de Marx. Foram entrevistados profissionais do municÃ­pio de ManhuaÃ§u e suas cidades limÃ­trofes. Pode-se perceber que o Projeto Ã‰tico PolÃ­tico se depara com fatores que dificultam sua materializaÃ§Ã£o diante de condiÃ§Ãµes precÃ¡rias de trabalho. Esta realidade reclama por mudanÃ§as e organizaÃ§Ã£o coletiva do profissional de ServiÃ§o Social.
UM RECORTE SOBRE A DEPRECIAÃ‡ÃƒO DO CAPITAL INTELECTUAL
Authors: Souza JosÃ© Carlos de , Moreira Rosane Aparecida , BrandÃ£o Rock Kleyber Silva
Published: July 2019

O presente artigo aborda aspectos ligados Ã  depreciaÃ§Ã£o do capital intelectual, um recorte da proposta de gestÃ£o do conhecimento. O seu objetivo Ã© descrever e analisar como os gestores, embora interessados em potencializar o valor agregado dos ativos intangÃ­veis, correm o risco deâ€œdepreciÃ¡-loâ€, pois parece que a gestÃ£o das pessoas como ativos quantificÃ¡veis remete a uma visÃ£o reducionista dos indivÃ­duos. Ã‰ que na busca de codificaÃ§Ã£o dos conhecimentos, sem o necessÃ¡rio cuidado e sem fugir Ã  espiral do modelo tradicional, Ã© possÃ­vel que as pessoas sepercam em meio aos indicadores de retorno dos investimentos, confundidas com aqueles ativos tangÃ­veis. Foi feita uma abordagem exploratÃ³ria em literatura alusiva ao modelo, buscando analisar o discurso da contabilizaÃ§Ã£o do capital humano, identificando riscos de sua depreciaÃ§Ã£o.
USO ABUSIVO DE ETANOL: UM COMPARATIVO ENTRE DADOS DA LITERATURA E A REALIDADE DA ZONA DA MATA MINEIRA
Authors: Rodrigues Anita S. , Vita Larissa de M. , Souza Juber P. de
Published: July 2019

O uso excessivo e indiscriminado de bebidas alcoÃ³licas pode causar dependÃªncia quÃ­mica e severos danos ao organismo humano. O consumo de bebidas alcoÃ³licas abrange mais de 2 bilhÃµes de pessoas em todo mundo e Ã© responsÃ¡vel por 3,2% das mortes no Brasil. NÃ£o obstante, bebidas constituÃ­das de Ã¡lcool etÃ­lico podem causar dependÃªncia quÃ­mica emindivÃ­duos hipersensÃ­veis. Este trabalho tem por objetivo avaliar que tipo de danos fisiolÃ³gicos e sociais causados pelo uso abusivo do etanol estÃ£o relatados na literatura e relacionÃ¡-los com a realidade dos dependentes quÃ­micos pertencentes ao grupo dos AlcoÃ³licos AnÃ´nimos de uma cidade da Zona da Mata mineira.
PROJETO CAF: UM PROJETO INTEGRADOR NO CURSO DE ANÃLISE E DESENVOLVIMENTO DE SISTEMAS
Authors: Cardoso Luciana Rocha , Souza Ezequias Ferreira de , Mendes AndrÃ©ia Almeida , Ventura Rita de CÃ¡ssia Martins Oliveira , Souza Reginaldo Adriano de , Araujo Glaucio Luciano
Published: July 2019

O Projeto CAF foi uma iniciativa da coordenaÃ§Ã£o do curso de AnÃ¡lise e Desenvolvimento de Sistemas do UNIFACIG juntamente com as assistentes sociais responsÃ¡veis pelo CAF; objetivou colocar em prÃ¡tica o conhecimento dos alunos e desafiÃ¡-los a buscar conhecimento alÃ©m do conteÃºdo ensinado em sala de aula, mostrando-os quais as etapas, as ferramentas e as dificuldades no desenvolvimento de um sistema, estimulando o trabalho em equipe, desde a parte de planejamento atÃ© a entrega do produto ao usuÃ¡rio final. Dividiu-se em seis fases, seguindo o modelo de desenvolvimento em cascata, em que, ao final de cada fase, em uma reuniÃ£o com o orientador/professor, os alunos apresentarÃ£o os documentos produzidos, momento em que foram avaliados e levados para possÃ­veis correÃ§Ãµes e, ao final de todas as etapas, tudo foi entregue como documentaÃ§Ã£o do sistema.
ALFABETIZAÃ‡ÃƒO VERSUS LETRAMENTO: ESCREVER, LER E PENSAR
Authors: Leblanck Raquel Hespanhol , FranÃ§a Silva Gustavo Thayllon
Published: July 2019

O presente artigo tem como objetivo analisar as diferenÃ§as existentes entre a Â alfabetizaÃ§Ã£o e o letramento, apontando a escrita, a leitura e o pensamento como prÃ©-requisitosÂ  fundamentais para erradicaÃ§Ã£o do analfabetismo funcional, uma triste realidade que precisa ser vencida no paÃ­s. A justificativa encontra-se na importÃ¢ncia que o letramento exerce na formaÃ§Ã£o de um cidadÃ£o capaz de desenvolver competÃªncias crÃ­ticas e ser um agente participativo e transformador frente Ã s necessidades cotidianas. De forma que esse seja capaz de fazer um bom uso da leitura em qualquer ambiente ou situaÃ§Ã£o.Â  Essa conscientizaÃ§Ã£o Ã© recente e o Brasil possui um nÃºmero elevado de analfabetos. A necessidade do letramento surgiu devido a insatisfaÃ§Ã£o com a simples alfabetizaÃ§Ã£o, importante reconhecer que o objetivo deste trabalho nÃ£o Ã© desvalorizar as escolas, pois as mesmas sÃ£o imprescindÃ­veis para o desenvolvimento social, mas apontar que Ã© atravÃ©s da junÃ§Ã£o dos dois eixos letramento e alfabetizaÃ§Ã£o que estÃ¡ o caminho para que as pessoas consigam escrever, ler e pensar de forma autÃ´noma e com eficiÃªncia. Somente atravÃ©s do incentivo a leitura Ã© que as escolas conseguirÃ£o promover cidadÃ£os capacitados a compreender o que leem e melhorar a desenvoltura dos mesmos para redigirÂ  e se expressar de maneira correta.
Automatic Text Segmentation and Recognition in Natural Scene Images Using Msocr
Authors: Samuel S.R. Surem , Seldev Christopher C. , Vinila S. Jinny
Published: July 2019

Introduction:

Segmentation and recognition of text from the scene image are a challenging
task due to blurred, low-resolution and small sized image.

Materials and Methods:

Innovative methods have been proposed to address this problem and to
recognize the text from the natural scene image. The acquired image is pre-processed by the YUV
channel conversion technique and the Y channel image is converted to a gray scale image. Connected
Component Based Text Segmentation Algorithm (CCBTSA) and MSER methods are used
for segmentation and recognition of text using Optical Character Recognition (OCR). GLCM and
FOS features are extracted from the segmented region. The Template matching algorithm is used
to extract the text character from the bounding box of the segmented image.

Results and Conclusion:

Trained SVM classifier is used to classify the image containing text and
non-text region. Performances are analyzed based on the recall rate, precision, accuracy, and Fmeasure.
From the experimental results, the accuracy of the proposed classifier was obtained as
95%.
Distribution of Quercetin in Different Organs of Male Sprague Dawley Rats Under Hypoxia: A High-Performance Thin Layer Chromatography Approach
Authors: Tripathi Ankit , Mishra Jigni , Bhardwaj Anuja , Misra Kshipra , Sagi Sarada S.K.
Published: July 2019

Background:

Quercetin (3’,3’,4,5,7-pentahydroxyflavonol), a natural flavonoid found in
fruits, vegetables, beverages, and other phytoproducts, exerts multiple health benefits including a reduction
in hypoxia-induced oxidative stress, inflammation, lipid peroxidation, allergic disorders,
neurodegenerative disorders, and cardiovascular diseases.

Objective:

Despite knowledge of such therapeutic efficacy of quercetin to human health, there is
limited literature available that sheds light on an organ-wise distribution of quercetin. Therefore, the
current study was performed to accurately estimate the distribution of quercetin in its supplemented
form in different tissues of a mammalian model, i.e., male Sprague Dawley (SD) rats.

Method:

The rats were exposed to different durations (1 h, 3 h, 6 h, and 12 h) of hypoxia
in a simulated hypobaric hypoxia chamber, with parameters maintained at 8 % O2 and 282 mm
Hg, following which they were sacrificed. Plasma and different tissue samples were duly collected.
A high-performance thin layer chromatography (HPTLC) approach was employed for the first time,
using our own reported method, along with an optimized sample preparation procedure for quercetin
determination. Briefly, the samples were developed in a mobile phase constituted of ethyl acetate,
dichloromethane, methanol, formic acid, and glacial acetic acid.

Results:

Distinct bands of quercetin in resultant HPTLC profiles verified that the
amount of quercetin varied among different tissues, with varying durations to hypoxia exposure.
Quercetin was substantially retained in vital organs namely, lungs, liver, and heart for relatively
longer durations.

Conclusion:

The present study established HPTLC as an efficient and high throughput tool, leading to
a satisfactory evaluation of the amount of quercetin present in various tissue samples under hypoxia.
THE INFLUENCE OF FINANCIAL PERFORMANCE AND NON FINANCIAL PERFORMANCE ON ISLAMIC CORPORATE SOCIAL RESPONSIBILITY DISCLOSURE: EVIDENCE FROM THE ISLAMIC BANKS IN INDONESIA
Authors: Siswanti Indra
Published: July 2019

The purpose of this study is to examine the influence of Financial Performance and Non Financial Performance on Islamic Social Responsibility Disclosure of the Islamic Banks in Indonesia. The sample used is 5 banks. The data in this study are secondary data, consists of annual reports of the Islamic banks for the periods of 2010 to 2017.Â  The analysis technique used is panel data regression. The results of fixed effect model state that duties and responsibilities of sharia supervisory board, compliance sharia principles have a significant influence on Islamic Corporate Social Responsibility disclosure, where as financial performance does not influence on Â Islamic Corporate Social Responsibility disclosure.Â Keywords: Corporate Social Responsibility, Social Islamic Reporting, Financial Performance, and Islamic Corporate Social Responsibility Disclosure
Social Media Strategies for Health Promotion by Nonprofit Organizations: Multiple Case Study Design (Preprint)
Authors: Vedel Isabelle , Ramaprasad Jui , Lapointe Liette
Published: July 2019

BACKGROUND

Nonprofit organizations have always played an important role in health promotion. Social media is widely used in health promotion efforts. However, there is a lack of evidence on how decisions regarding the use of social media are undertaken by nonprofit organizations that want to increase their impact in terms of health promotion.

OBJECTIVE

The aim of this study was to understand why and how nonprofit health care organizations put forth social media strategies to achieve health promotion goals.

METHODS

A multiple case study design, using in-depth interviews and a content analysis of each social media strategy, was employed to analyze the use of social media tools by six North American nonprofit organizations dedicated to cancer prevention and management.

RESULTS

The resulting process model demonstrates how social media strategies are enacted by nonprofit organizations to achieve health promotion goals. They put forth three types of social media strategies relative to their use of existing information and communication technologies (ICT)—replicate, transform, or innovate—each affecting the content, format, and delivery of the message differently. Organizations make sense of the social media innovation in complementarity with existing ICT.

CONCLUSIONS

For nonprofit organizations, implementing a social media strategy can help achieve health promotion goals. The process of social media strategy implementation could benefit from understanding the rationale, the opportunities, the challenges, and the potentially complementary role of existing ICT strategies.