bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the Influence of The 7P Marketing Mix on Customer Satisfaction of Bikla Coffee, Jember District
Authors: Wardani Renata Dian Kusuma , Soedarto Teguh , Syah Mirza Andrian
Published: July 2024

The marketing mix is one of the strategies that must be developed to build the image of a business so that it can be a factor in increasing customer satisfaction. Consumer satisfaction refers to the degree to which an individual's actual state is influenced by comparing the apparent look of a product to their assumptions. Increasing customer satisfaction is a fundamental aspect of the sustainability of a business. Many industries have an impact on competition between businesses, so every business tries to make its customers feel satisfied. This research attempts to examine the effect of the marketing mix simultaneously and partially on customer satisfaction and measure the level of customer satisfaction. This research was conducted in Jember district from February 2024 to March 2024. The study used quantitative methods with a survey approach. This study's primary and secondary data sources are primary and secondary. Accidental sampling, a non-probability sampling technique, is utilized by the sampling approach. The data analysis approach used was the SEM (Structural Equation Model) and CSI (Customer Satisfaction Index), which used 68 respondents. The study findings reveal that the coefficient of determination (R square) is obtained at 0.578, or when percent, there are 57.8 percent. Variables that affect customer satisfaction. Partially, the price variable (X2), promotion (X4), process (X6), and physical evidence (X7) have a significant effect on customer satisfaction, while the product variable (X1), place (X3), people (X5) have no significant effect. In addition, the results of calculating the level of satisfaction of BIKLA coffee consumers show a CSI value of 79.86%, indicating that consumers are satisfied with the services provided.
Analisa Kelayakan Usaha Tani Aren di Kecamatan Lareh Sago Halaban Kabupaten Lima Puluh Kota
Authors: Yulistriani Yulistriani , Edwin Edwin , Hasibuan Halimatus Syahdia , Wisnubroto Muhammad Parikesit , Rezki Dewi
Published: July 2024

Indonesia has a potential for diversity in agricultural commodities and a tropical climate. Sugar palm is a commodity that has the potential to be developed. Opportunities for developing sugar palm agribusiness are still broad, from providing production inputs such as seeds, planting (the farm), harvesting, processing products, marketing,  and supporting subsystems. Almost all palms are used and can be used for various needs. This research aims to analyze the feasibility of sugar palm farming in Lareh Sago Halaban District, Kab. Lima Puluh Kota. The quantitative research method calculates revenue, cost, and feasibility analysis of sugar palm farming. The research results show that the average fixed cost of sugar palm farming is IDR. 54.951.667 per hectare per year. The average variable cost of sugar palm farming is IDR. 20,233,333. The total average production cost of sugar palm farming is IDR. 75.185.000. The total revenue of sugar palm farming is IDR. 310,658,000 per hectare per year, consisting of fresh sap at IDR. 102,200,000 per hectare per year, palm sugar at IDR. 62,458,000 per hectare per year, and sugar palm at IDR. 146,000,000 per hectare per year. The R/C ratio for fresh sap is 1.35. For palm sugar, it is 0.83, and for ant sugar, it is 1.95. The feasibility analysis concluded that sugar palm farming is generally economically profitable, as evidenced by the feasibility values of fresh sap and palm sugar, which are greater than 1. Of the three products produced, palm sugar has the highest feasibility value (R/C = 1.95). In contrast, palm sugar has the lowest feasibility value or is not feasible with an R/C value of 0.83, which is less than 1.
The role of court guardians in proceedings under the 1980 Hague convention on the civil aspects of international child abduction. Issues selected in the light of a case files’ research
Authors: Schulz Anna
Published: July 2024

The 1980 Hague Convention on the Civil Aspects of International Child Abduction only regulates in a very general way certain elements of the proceedings pending under this treaty. Each state-party regulates procedural details in this respect mainly in accordance with their own domestic law. The article furnishes facts and data about results of the state of the application of the Convention in Poland and tasks carried out by a court guardian and a state official.
Cross-border Hague proceedings are not a classic guardianship process. However, an appointed court guardian applies steps similar in nature to those derived from typical domestic guardianship and family cases. The office acts as an information source, it supervises the course of contacts and, if necessary, it is responsible for the compulsory collection of a child. Those tasks are not strictly regulated in the Convention. This article aims to show the actual level of participation of court guardians in Hague proceedings in Poland, and to examine to what extent the best interests of children might be affected by the actions of court guardians.
A concept at the edge of national and European constitutional law: different understandings within the same region. Constitutional identity in Poland and Hungary
Authors: Szentgáli-Tóth Boldizsár
Published: July 2024

The Polish Constitution does not expressly postulate the term of constitutional identity, however the Constitutional Tribunal of Poland has elaborated this concept in detail in its case law. This framework has been used to justify internal reforms; however, it has been mostly applied as a constitutional argument for the protection of national sovereignty within the European legal space.Similarly, the Hungarian Constitutional Court has stated: The constitutional identity of Hungary does not constitute the exhaustive and closed list of values, but some of its elements may be highlighted as examples, which are identical with the recently acknowledged constitutional values: the fundamental rights; the separation of powers; the republican form of state; the freedom of religion; the rule of law; parliamentarian; equality under the law; the respect of the judicial power; and the protection of the nationalities living together with us. My study aims to make a comparison between the relevant case-law of the two constitutional courts and provide some recommendations on how constitutional identity should be reconceptualized; separated more clearly from other forms of identity; and how it could fulfil its task more efficiently at the edge of the national and European legal orders with the help of European-wide standards.
WEBINAR THE BEST PRACTICE PENDIDIKAN ISLAM MULTIKULTURAL DALAM HARMONISASI KEHIDUPAN MASYARAKAT DI INDONESIA
Authors: Riza Muhammad
Published: July 2024

Kemajemukan masyarakat Indonesia yang kaya akan budaya dan agama menjadikan pendidikan multikultural sebagai sebuah keniscayaan dalam rangka mengajarkan para peserta didik untuk memahami, menghargai, dan merayakan perbedaan. Dengan nilai-nilai toleransi, inklusivitas, dan keadilan sosial, pendidikan multikultural membantu menciptakan masyarakat yang lebih inklusif, toleran, dan siap menghadapi tantangan kompleks yang dihadapi oleh Indonesia saat ini. Pengabdian ini dilaksanakan melalui tiga tahapan penting, yaitu perencanaan, pelaksanaan, dan diskusi, dengan tujuan utama untuk menyebarkan praktik terbaik Pendidikan Islam Multikultural. Peserta yang terlibat dalam pengabdian ini mencakup para guru dari lingkungan madrasah di wilayah Aceh Tengah, mahasiswa, dan kalangan umum yang tertarik dengan isu pendidikan multikultural. Narasumber utama dalam webinar ini adalah Dr. Hepi Ikmal, M. Pd. I, yang membahas peran Pendidikan Islam Multikultural dalam proses deradikalisasi mantan narapidana teroris, serta Dr. Muhammad Riza, MA, yang mengulas Pendidikan Islam Multikultural di Dayah dalam konteks resolusi konflik di Aceh. Hasil dari pengabdian ini memberikan wawasan yang berharga bagi para peserta mengenai bagaimana Pendidikan Islam mampu mengimplementasikan nilai-nilai pendidikan multikultural dalam rangka menciptakan kerukunan dalam masyarakat. Diskusi dalam webinar juga memberikan ruang bagi partisipan untuk berbagi pandangan dan pengalaman mereka. Dengan demikian, pengabdian ini membantu mempromosikan pemahaman yang lebih baik tentang pentingnya pendidikan multikultural dalam mencapai harmoni dan kerukunan dalam masyarakat Indonesia yang beragam.
Highly-effective removal of methylene blue dye using Cocoa (Theobroma cacao L.) Pods modified with HCl: Optimization using response surface methodology
Authors: Kana Dénise Félicité  , Rahmino ABDOUL NTIECHE , Lekene Ngouateu René Blaise  , Murat Yilmaz  , Ndi Julius Nsami  , Kouotou Daouda
Published: July 2024

In this study, the cocoa pods modified with hydrochloric acid (CCA) was prepared and used as bio sorbent for methylene blue (MB) removal in aqueous solution. The CCA was characterized by Fourier Transformed Infrared (FT-IR) spectroscopy, Scanning Electron Microscopy (SEM) and pH of point zero charge (pHpzc). The response surface methodology-full factorial design (RSM-FFD) approach was used to investigate the most influential biosorption parameters and optimize their effects on MB adsorbed quantity. The linear and non-linear regression have been used to find the best fit of isotherms and kinetics models. The optimum sorption parameters were found to be 6.0, 240 mg/L and 30 mg for the pH, MB initial concentration and adsorbent dose respectively. Under these optimum conditions, the MB adsorbed quantity was found to be 150.45 mg/g. The RSM-FFD based on the ANOVA revealed that, there was a good fit between the experimental and predicted values respect to the probability (P<0.05) and with 95% degree of confidence. The polynomial equation well explained the synergetic and antagonistic effects of examined factors on MB adsorbed quantity onto CCA. The Freundlich, D.K.R and Temkin isotherms models in one hand, the pseudo-first and pseudo-second order kinetics in order hand gave the best fit for the non-linear MB sorption data. These results demonstrated that, the CCA is a promising, low-cost and eco-friend sorbent for dyes remediation in aqueous medium.
RESPON KONSENTRASI NUTRISI AB-MIX DAN INTERVAL WAKTU PEMBERIAN PLANT GROWTH PROMOTING RHIZOBACTERIA (PGPR) PADA SISTEM TANAM HIDROPONIK TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN SELADA MERAH (Lactuca Sativa L Var. Red Lettuce)
Authors: Bahi Tomi , Prasetyo IK , Muddarisna Nurul
Published: July 2024

This research was conducted to study the effect of ab-mix nutritional concentrations and the time interval for administering plant growth promoting rhizobacteria (pgpr) in the hydroponic planting system on the growth and production of red lettuce (lactuca sativa l var. Red lettuce). The experiment used a randomized block design (RBD) consisting of two factors of four replications. The first factor is: with 3 time intervals of giving plant growth promoting rhizobacteria (PGPR): P1 = (7, 14, 21 hst) P2 = (8, 15, 22) P3 = (9, 16, 23). The second factor is: concentration of AB-mix with 3 levels, namely: A1 = concentration of AB-mix 5 ml / L of water, A2 = concentration of AB-mix 6 ml / L of water, A3 = concentration of AB-mix is ​​7 ml / L of water. The administration of PGPR showed a significant effect on the parameters of the treatment for the number of leaves 28, 35, 42 dd, and leaf area 28 dd. The provision of AB-mix nutrition showed a significant effect on plant height at the age of 35 days after observation. The provision of PGPR and AB-mix nutrition showed a significant interaction between the two treatments, namely the observation parameters of plant height with the addition of PGPR (7, 14, 21 dst) time interval treatment and the AB-mix concentration of 6m / l observation age 7, 21, 35 , 42 days after planting, the number of leaves at the time interval for adding PGPR (9, 16, 23 dd) and the AB-mix concentration of 7ml / l pengamtan 42 dd, as well as the leaf area of ​​the time interval for adding PGPR (8, 15, 22 dd) and AB-mix concentration 7 ml / l at the age of observation 21, 28, 35, and 42
PENGARUH DOSIS PUPUK KALIUM DAN FREKUENSI PENYIRAMAN AIR PADA BIOMASSA AKAR DAN KANDUNGAN SAPONIN AKAR TANAMAN GINSENG JAWA (Talinum paniculatum Gaertn.)
Authors: Sa'idah Nurul , Muddarisna Nurul , Sri Rahayu Yekti
Published: July 2024

The root of the Javanese Ginseng plant (Talinum paniculatum Gaertn) is one of the medicinal plants used because it contains saponins. Efforts are needed to increase saponin content in plant roots. This study aims to determine the effect of potassium fertilizer dosage and frequency of watering on root biomass and saponin content of Javanese ginseng (Talinum paniculatum Gaertn.). The study was started from March to May 2019. This study used a randomized block design (RBD) arranged in a factorial manner. The first factor the frequency of watering (A) consists of 4 levels, namely A1 = watering once a day, A2 = watering once every 3 days, A3 = watering once every 5 days, A4 = watering once every 7 days, while the second factor is the dose of potassium fertilizer (K) consists of of 4 levels, namely K0 = 0 kg KCl / ha, K1 = 500 kg KCl / ha, K2 = 750 kg KCl / ha, so there are 12 treatments, each treatment is repeated 3 times. The data obtained were analyzed statistically using the F test with a level of 5% and continued test of LSD 5%. The results showed that the application of potassium fertilizer at a dose of 750 kg KCl / ha with watering every 7 days resulted in the highest saponin content among other treatments. while the application of potassium fertilizer at a dose of 750 kg KCl / ha with watering once a day produced the highest biomass compared to other treatments
Uji efektivitas antibakteri ekstrak daun kayu hitam (Diospyros celebica Bakh.) terhadap bakteri Staphylococcus aureus dan Salmonella typhi
Authors: M. Guli Musjaya , Priyandini Nabila , Lambui Orryani , Ardiputra Muh.Akbar , Toemon Agnes Immanuela
Published: July 2024

Diospyros celebica leaf extract can inhibit the growth of Staphylococcus aureus and Salmonella typhi bacteria. This research aims to determine the ability of D. celebica leaf extract to inhibit the growth of S. aureus and S. typhi bacteria. S. aureus and S. typhi were grown in NA media and then given leaf extract with concentrations of 10%, 20%, 30% and 40% using the well method. 2% chloramphenicol added to the bacterial growth medium was used as a control. The results showed that the leaf extract from D. celebica has a strong inhibitory power to inhibit the growth of S. aureus and S. typhi bacteria.
Nutritional and bioactive characterization of pistachio—a review with special focus on health
Authors: Ripari Garrido Juliana , Patrignani Mariela , Puppo María Cecilia , Salinas María Victoria
Published: July 2024

The objective of this work was to compile data for the characterization of pistachio’s chemical composition and to analyze the benefits of their consumption in the diet. Pistachio edible seed is cultivated mainly in America, Mediterranean countries and Middle East. The geographical precedence may affect its mineral content as well as its lipidic profile and it may also influence the content of bioactive compounds. Pistachio presents a high proportion of vitamins, carotenoids, polyphenols, and flavonoids that have been associated with pistachio health benefits such as its antioxidant and anti-inflammatory activities. Pistachio intake would reduce glycemic index and control Type-2 Diabetes Mellitus. Clinical studies have also indicated that the presence of phytosterols, monounsaturated fatty acids (MUFAs) and dietary fiber from pistachio grains may reduce the risk of cardiovascular diseases (CVDs). Furthermore, the main wastes of pistachio industry [pistachio green hull (PGH) and pistachio shell (PS)] could be also considered a good source of bioactive compounds. Recent studies showed that the encapsulation of these nutraceutical compounds of PGH may be a green strategy for manufacture high-value foods within the framework of circular economy. Moreover, PS can be considered a good source of cellulose nanocrystals (CNC) that may be used for encapsulation and stabilization of oil-water emulsions.
A narrative review on perioperative systemic therapy in non-small cell lung cancer
Authors: Hsu Robert , Arter Zhaohui Liao , Poei Darin , Benjamin David J.
Published: July 2024

Non-small cell lung cancer (NSCLC) that is operable still carries a high risk of recurrence, approaching 50% of all operable cases despite adding adjuvant chemotherapy. However, the utilization of immunotherapy and targeted therapy moving beyond the metastatic NSCLC setting and into early-stage perioperative management has generated tremendous enthusiasm and has been practice-changing. Adjuvant atezolizumab in NSCLC first demonstrated a clinical benefit with an immune checkpoint inhibitor. Then, with studies studying a significant benefit in major pathologic response in surgical patients treated preoperatively with immunotherapy compared to only chemotherapy, neoadjuvant nivolumab and chemotherapy were evaluated and showed significant event-free survival benefit leading to subsequent studies evaluating perioperative immunotherapy and chemotherapy. Meanwhile, with regards to targeted therapies, adjuvant osimertinib in EGFR-mutated NSCLC and adjuvant alectinib in ALK-rearranged NSCLC have both received regulatory approvals following demonstrated clinical benefit in clinical trials. With rapidly evolving changes in the field, new combinations such as multiple immunotherapy agents and antibody-drug conjugates in development, perioperative NSCLC management has quickly become complicated with different pathways to perioperative treatment. Furthermore, circulating tumor DNA and studies looking at better tools to prognosticate immunotherapy response will help with decision-making regarding which patients should receive immunotherapy and if so, either only pre-operatively or both pre- and post-operatively. In this review, we look at the evolution of systemic therapy in the perioperative setting from adjuvant chemotherapy to adjuvant immunotherapy to perioperative immunotherapy and look at perioperative targeted therapy while looking ahead to future considerations.
The Finite Element Method for the Elasticity of Micro-pores Material
Authors: Arman Arman , Eso Rosliana
Published: July 2024

This study aimed to investigate micro-pores' impact on the elastic energy of materials using open-source simulation. The finite element method analyzed linearly elastic, homogeneous, and isotropic materials. The domain is modeled as an isotropic elastic material with a constant thickness and is treated as a two-dimensional rectangular plate. The positions and diameters of the micro-pores were varied. The results indicate that the position and diameter of the micro-pores within the domain significantly influence the magnitude of elastic energy. Larger pore diameters correspond to higher values of elastic energy. Additionally, the elastic energy value of the micro-pores remains relatively constant, though it is smaller when the pores are located at the ends of the material. This suggests that the elasticity at the end of the material is reduced due to pressure-induced movement. Furthermore, varying the diameter of the micro-pores leads to more noticeable changes in material shape, with larger diameters resulting in more pronounced alterations.
Seguridad ocupacional en producción de combustible alternativo mediante pirólisis de neumáticos reciclados: técnicas innovadoras
Authors: Llumiquinga Jefferson ,   Universidad Central del Ecuador, Pichoasamin Diego ,   Instituto Superior Tecnológico Universitario Rumiñahui
Published: July 2024

La pirólisis de neumáticos usados ha surgido como una opción prometedora ante la creciente necesidad de encontrar soluciones sostenibles para la gestión de residuos. El objetivo prin-cipal de este estudio es analizar la seguridad ocupacional de la producción de combustible alternativo mediante la pirólisis de neumáticos usados en una planta piloto en la parroquia Sangolquí-Ecuador. La metodología incluyó la revisión de literatura, la realización de análisis de riesgos y la propuesta de medidas de mitigación específicas para cada etapa del proceso de pirólisis. Los principales resultados destacan la identificación de riesgos clave, como la exposi-ción a altas temperaturas, la presencia de productos químicos tóxicos y el manejo de materiales inflamables. Mediante las medidas de mitigación adecuadas, como el uso de equipos de pro-tección personal, la capacitación del personal en seguridad ocupacional y la implementación de procedimientos de trabajo seguro, se puede garantizar un entorno laboral seguro y saludable. Este estudio subraya la importancia de priorizar la seguridad ocupacional en la industria de la pirólisis de neumáticos usados. Se recomienda la promoción de una cultura de seguridad y cum-plimiento normativo en todas las etapas del proceso de pirólisis para garantizar la sostenibilidad a largo plazo de esta industria.
Sosialisasi Anti Perundungan pada Siswa Kelas 4C SD Negeri 75 Kota Bengkulu melalui Film Pendek Anti Perundungan (Gerobak Perdamaian)
Authors: Lubis Syahrika Ardiyani , Heriyanti Lesti , Ledyawati Ledyawati
Published: July 2024

Bullying or negotiation is a word that has a meaning as an unpleasant action verbally or non-verbally. In the world of education, negotiation is a dynamic thing because it is a challenge for educators to shape the character of students. This negotiation problem often occurs in the school environment with students as the main actors. Therefore, this research is aimed at examining the socialization carried out on class 4C students at SD Negeri 75 Bengkulu to prevent the behavior of negotiation actions that occur in the school environment. As a result of this negotiation which is also a very detrimental victim, learners who are victims of negotiation are more likely to close themselves, feel insecure, and are not eager to go to school. The method of implementing socialization includes: preparation, implementation and presentation. This socialization is supported by the class teacher because it is considered as one of the character education for students and adds insight to students related to the material. It is expected that students who are victims of negotiations will be more courageous to voice their complaints to their class teachers.
Facilitating learner reflection: Online goal setting and self-evaluation in Japanese higher
education
Authors: Emerson Nicolas
Published: July 2024

The aim of this study was to investigate student preferences and usage patterns of a custom web application designed for goal setting and self-evaluation, implemented within compulsory English as a Foreign Language (EFL) classes at a higher education institution in Japan. This application was introduced to support learner reflection, with the goal of enhancing student performance and reducing course repetition rates. Analysis of the web
application usage data from 88 participants revealed that students choosing more challenging goals consistently rated their performance higher in self-evaluations (p < .001) than those opting for easier goals. Furthermore, data from closed-ended questionnaire responses showed a strong preference among students for the online platform over traditional paper-based methods for goal setting and self-evaluation (p < .001). While these results underscore the potential of such an approach in enhancing academic outcomes, the study’s modest scale necessitates broader research for validation. Examining actual achievement data with a larger cohort would offer a more comprehensive understanding of the efficacy and broader implications of these methods.
System features of the object composition of cybernetic law
Authors: Tsymbalyuk Vitaly
Published: July 2024

The article offers for consideration separate results of the study of the object composition of cyber law. Separate norms of Ukrainian legislation on cyber security are analyzed. Definitions of the following leading subject categories are proposed: cyber law; cyberspace, cyber security.

As a doctrinal position, the definition of the essence of law of cybernetic (cyber law, cyber-law) is proposed, its three interrelated components: the sphere of social relations, including those that find expression in public law; direction of scientific research in jurisprudence; academic discipline.

According to the content, the following formulation of cyber law is proposed.

Cybernetic law is a set of norms that determine: the basics of organizing the support of vital national interests in cyberspace the relationship between the needs of a person, a citizen, society, and the state; main goals, directions and principles of state policy; principles of authority of state bodies, enterprises, institutions, organizations of all forms of ownership, coordination of their activities in relation to cyber security.

Based on the analysis of individual theoretical-applied publications, it is substantiated that currently the definition of the content of cybernetic law should be dominated by the scientific position of assigning it, as a legal phenomenon, to a sub-branch as part of a special part of information law. At the same time, it cannot be ruled out that in the future the concept of this right may acquire systemic features of a conditionally autonomous special field of law, which is extrapolated by objective features to the relevant institutes of such leading branches of law as: criminal law, administrative law, civil law.

Key words:law, cyber security legislation, cyber space, cyber law.
Reliability of a probabilistic knowledge structure
Authors: de Chiusole Debora , Granziol Umberto , Spoto Andrea , Stefanutti Luca
Published: July 2024

Indexes for estimating the overall reliability of a test in the framework of knowledge space theory (KST) are proposed and analyzed. First, the possibility of applying in KST the existing classical test theory (CTT) methods, based on the ratio between the true score variance and the total variance of the measure, has been explored. However, these methods are not suitable because in KST error and true score are not independent. Therefore, two new indexes based on the concepts of entropy and conditional entropy are developed. One index is used to estimate the reliability of the response pattern given the knowledge state, while the second one refers to the reliability of the estimated knowledge state of a person. Some theoretical considerations as well as simulations and an empirical example on real data are provided within a study of the behavior of these indexes under a certain number of different conditions.
Vitamin B12 Deficiency in Neurological Disorders of Older Adults: Etiology, Diagnostics, Treatment
Authors: Cherdak M. A. , Mkhitaryan E. A.
Published: July 2024

One of the common problems associated with aging is vitamin B12 (cobalamin) deficiency. According to some reports, it is present in every third person over the age of 60. Cobalamin is involved in numerous biologically important reactions, and its deficiency manifests itself in a range of disorders, including hematological and gastrointestinal symptoms, as well as pathology in various parts of the nervous system. The article discusses clinical variants of neurological disorders related to vitamin B12 deficiency, such as damage to both the peripheral and the central nervous systems. The relationship between cobalamin deficiency and the development of cognitive and other neuropsychiatric disorders in older individuals is discussed. Data on specific causes of vitamin B12 deficiencies in older individuals, including iatrogenic factors, are presented. Modern approaches to the diagnosis and correction of cobalamin deficiency are outlined, taking into account the characteristics of the geriatric population.
Взаимосвязь гипогликемии и когнитивных нарушений у пожилых пациентов с сахарным диабетом 2 типа
Authors: Bulgakova S. V. , Merzlova P. Ya. , Kurmaev D. P. , Treneva E. V.
Published: July 2024

Type 2 diabetes mellitus (T2DM) is one of the most common chronic non-communicable diseases, and the rate of increase is higher than predicted. This is an age-associated disease that is more common among older patients, whose proportion is also increasing in both absolute and relative age groups. Despite advances in the treatment of T2DM and a wide range of hypoglycemic drugs, complications of this disease, primarily micro- and macrovascular, remain a public health problem. It is also known that T2DM is a risk factor for the development of dementia. Furthermore, there remains a significant prevalence of hypoglycemia among patients with T2DM who are undergoing hypoglycemic therapy. This poses a potential threat to older patients, increasing their risk for cardiovascular events and exacerbating cognitive impairments, because glucose is the primary energy substrate for the nervous system. Understanding the impact of hypoglycemia on the development of dementia in older patients and how these events interact, as discussed in this review, can further assist in developing prevention and risk minimization strategies.
A Novel Functional Status-Oriented Method for Assessing Operative Risk in Older Patients Undergoing Coronary Artery Bypass Grafting
Authors: Grishenok A. V. , Buziashvili V. J. , Matskeplishvili S. T. , Buziashvili J. I. , Koksheneva I. V. , Gvalija S. L.
Published: July 2024

Background. Currently, there is no standardized method for assessing risk before cardiac surgery in older individuals. Recognized operative risk scales do not consider the features of older patients.

Aim. To create a scale that can forecast early postoperative outcomes after coronary artery bypass grafting in patients aged over 75 by conducting a comprehensive geriatric assessment.

Materials and methods. The study enrolled 83 patients aged 75 and older who required myocardial revascularization, with emergency surgery cases as the exclusion criteria. In addition to the standard screening, all patients underwent comprehensive geriatric assessment, including frailty screening, cognitive assessment, depression screening, grip strength, and short physical performance battery test (walking speed, sit-to-stand performance, standing balance).

Results. Six mathematical models predicting coronary artery bypass grafting outcomes were developed: duration of mechanical ventilation (р=0,012), length of stay in intensive care unit (р<0,001), duration of bed rest after surgery (р<0,001), duration of inotropic support (р<0,001), risk of acute cerebrovascular accident (р=0,015), postoperative length of stay (р=0,003). Within Microsoft Excel, mathematical models were used to devise the «Geriatric prognostic scale» for anticipating early postoperative outcomes post coronary artery bypass grafting. To estimate the risk, the following data must be entered: walking speed (m/s), grip strength (kg), sit-to-stand performance (sec), standing balance (sec), total score on the Brief Physical Functioning Test Battery, and total ejection fraction using the Simpson method (%).

Conclusion. The developed method allows for the early prediction of outcomes in coronary artery bypass grafting for patients over 75 based on functional status. This is a significant addition to traditional risk scales, which do not consider the features of older patients. The method is straightforward to implement and can be applied independently by the patient's treating physician.
Combination Drug Therapy for the Management of Alzheimer’s Disease
Authors: Dudchenko N. G. , Mkhitaryan E. A.
Published: July 2024

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases worldwide. It is the leading cause of dementia in both older and oldest old population. The standard treatment for AD dementia is based on two groups of drugs: cholinesterase inhibitors (donepezil, rivastigmine, galantamine) and NMDA glutamate receptor modulator memantine. At moderate and severe stages of dementia, it is often necessary to use both a cholinergic inhibitor and memantine simultaneously. This review discusses current capabilities, efficacy and safety of combined therapy for Alzheimer's. It also covers details the features of using fixed combinations of donepezil and memantine in clinical practice.
Associations between vitamin D and depression in institutionalized oldest old
Authors: Isaev R. I. , Vorobyeva N. M. , Mkhitaryan E. A. , Marahovskaya E. A. , Tkacheva O. N.
Published: July 2024

Aim. To examine the relationship between vitamin D levels and the prevalence and severity of depression in people aged ≥90 living in the nursing homes.

Materials and methods. A cross-sectional study was conducted on 351 people (25% men) aged 90-104, with a median age of 92, who were permanently residing in Moscow nursing homes. The Geriatric Depression Scale (GDS-15) was used to detect depression, with possible depression diagnosed at a score of 5. Vitamin D (25-hydroxycalciferol) levels were determined in blood serum using chemiluminescence analysis on microparticles, with normal levels ranging from 30 to 100 ng/ml.

Results. Depression is diagnosed in 67,2% of the oldest old. Vitamin D levels range from 3 to 36 ng/ml (median 6, interquartile range 5-8), and less than 1% of those with the highest vitamin D levels have a vitamin D deficiency. The absolute median difference in vitamin D between the oldest with and without depression is 2 ng/ml (p<0.001). A single-factor regression analysis shows that vitamin D in the institutionalized oldest old has a protective effect on depression: increasing vitamin D levels per 1 ng/ml reduces the chance of depression by 14% (OR 0,86; 95% CI 0,81-0,92; p<0,001). After adjusting for age, sex, children, education, and physical activity in the regression model, the association between vitamin D and depression remains significant for both vitamin D and high levels of physical activity as predictors of depression with protective effect: vitamin D (OR 0,86; 95% CI 0,80-0,93; p<0,001); high level of physical activity (OR 0,47; 95% CI 0,27-0,81; p=0,007). ROC analysis confirms a correlation between vitamin D and depression. Vitamin D levels ≤12 ng/ml predict depression levels with 71% sensitivity, 70% specificity, and 71% diagnostic accuracy. The ROC-curve area below 0.666 indicates a satisfactory model quality. The single-factor regression analysis shows that the chances of depression are 5,6 times higher at vitamin D levels of ≤12 ng/ml (OR 5,60; 95% CI 2,47-12,70; p<0,001).

Conclusion. Associations between vitamin D and the presence and severity of depression among the oldest old living in the nursing homes in Moscow have been identified.
Exploring lecturers’ ways in assessing students’ English writing
Authors: Netta Ayuna , Trisnawati Ika Kana , Fitara Reka , Asma Asma
Published: July 2024

This study aimed to identify the ways lecturers assessed students’ English writing. The respondents of this study were two lecturers teaching Writing course at English Education Department of Universitas Muhammadiyah Aceh. This study employed interview as the instrument to collect data. Data were analyzed by using thematic analysis. The findings of the study revealed that the lecturers employed analytic rubrics when evaluating their students’ writing. The findings suggest that rubrics are effective to evaluate the students’ writing for its reliable scoring system. This study is expected to provide insights for other lecturers in terms of evaluating writing using assessment rubrics in English classroom.
Pendampingan Pelaksanaan Uji Kompetensi Keahlian Mandiri Bidang Bisnis Daring dan Pemasaran
Authors: Nurendah Yulia
Published: July 2024

UKK (Skill Competency Test) is implemented to fulfill the mandate in government regulation number 19 of 2005 concerning national education standards. National education standards (SNP) are the minimum criteria for the education system throughout the jurisdiction of the Unitary State of the Republic of Indonesia. The Mentoring Activity for the Implementation of the Independent Skill Competency Test for Online Business and Marketing Competencies was carried out at SMK Kamandaka on March 5-6, 2024 which was held for 2 days. The number of Participants in the Independent Skill Competency Test for Online Business and Marketing Competencies at SMK Kamandaka was 24 Participants on the first day and 12 Participants on the second day.
 
Keywords: UKK, Online Business and Marketing
Research at the Crowding and Tourism
Authors: Kainthola Snigdha , Singh Kaurav Rahul Pratap
Published: July 2024

This study aims to conduct a bibliometric analysis of existing literature on crowding in tourist destinations and its effects, thereby recognizing areas for further research. The authors evaluated 421 Scopus-indexed documents related to the subject of crowding. This study involved analysing the annual publications on the topic and the past trends to suggest solutions for better management of the destinations in the future. The results reveal a noticeable rise in the academic literature on crowding, especially about popular tourist destinations. The findings also indicate that unmonitored tourism and subsequent media coverage have significantly contributed to this upswing in scholarly work. The problem of crowding disappeared for a short period during the COVID-19 pandemic. This research note explores a possible solution to the problem to be utilised in the future and comments on the changing nature of the psychological concept after COVID-19. This study offers a comprehensive review of the current state of research on crowding, thereby helping to guide future research in this area. Moreover, it underscores the need for strategies to manage crowding to promote sustainable tourism.
Participant Satisfaction in Dark Immersive Theatre Experiences
Authors: Belo Miguel , Gustavo Nuno
Published: July 2024

The term ‘immersive theatre’ has become popular to describe a growing trend in contemporary performances. In recent years, there has been a significant increase in the popularity of Dark Immersive Theatre Experiences (DITE), which combine immersive theatre and darkness. As a result, it has become more important for practitioners and the scientific community to understand the factors that enhance or limit participants' satisfaction. In this study, a qualitative approach was used to identify five critical obstacles to participant satisfaction: the size of the audience, downtime occurrences, the attitude of other participants, unclear instructions, and the conceptual framework of the experiences. Additionally, five key catalysts that enhance participant satisfaction were found: the intensity of darkness, sensations of achievement, the ambience surrounding the experience, the incorporation of theatrical elements, and the presence of game elements. This research provides valuable insights for DITE managers and other practitioners to develop successful future experiences.
Competencias Digitales y Desempeño en Docentes de Educación Secundaria, Ventanilla-2021
Authors: Allca-Quispe Fernando Pedro
Published: July 2024

Objetivo: Esta tesis doctoral buscó determinar la relación que existe entre las competencias digitales y el desempeño docente en los profesores del nivel de educación secundaria de la jurisdicción de la Red Nº01 perteneciente a la UGEL Ventanilla -2021. Método: la investigación fue básica y se trabajó con un diseño no experimental. Se identificó como unidad de análisis al docente, abarcando un total de 257 profesores de nivel secundario pertenecientes a las Instituciones Educativas de la Red Nº 01 de la UGEL del distrito de Ventanilla. El análisis de datos se llevó a cabo mediante el programa SPSS V.26. Resultados: Los resultados del coeficiente de correlación Rho de Spearman revelaron una relación significativa y positivamente alta (p=,000; Rho=,781) entre las competencias digitales y el desempeño docente. Esto sugiere que el fortalecimiento de las competencias digitales podría mejorar el desempeño de los docentes de nivel secundaria en la UGEL N°1 de Ventanilla. Conclusión: Se puede afirmar que mejorar las competencias digitales de los profesores de nivel secundaria de las instituciones educativas pertenecientes a la RED N°01 de Ventanilla resultará en una mejora proporcional y significativa en el desempeño docente (Rho=,781; p=,000<0,05). Se recomienda que el Ministerio de Educación persista en la provisión de tecnología y formación para los profesores sobre cómo crear y utilizar recursos digitales. Las capacitaciones deben iniciar con sesiones presenciales para docentes con limitados conocimientos tecnológicos y asegurarse de incluir acceso a internet de banda ancha.
Diseño de un Viscosímetro para Estudios de Reología
Authors: Cancho Guisado Jaime Antonio , Moro Pisco Jose Francisco , Rodriguez Figueroa Jose Julio , Flores Masias Edward José , Soberón Tomasto Victor Leonardo , Cano Contreras Pierre Anibal
Published: July 2024

Todo fluido se deforma continuamente por efecto de los esfuerzos cortantes. La viscosidad es una propiedad física de los fluidos, quienes se mueven en diferentes velocidades, en su movimiento se origina la colisión de sus partículas, provocando la ralentización, desaceleración o la resistencia en su desplazamiento. El objetivo del presente trabajo es Diseñar un viscosímetro para facilitar los estudios de Reología de los fluidos, mayores a 480 cP, en el laboratorio de fluidos de la Facultad de Ingeniería Electrónica e informática de la Universidad Nacional Federico Villarreal, obteniendo la caracterización de las propiedades reológicas e identificando la variación de los rangos de temperatura aplicados a los fluidos. Se utilizó la metodología de investigación tomando en cuenta: el ámbito espacial y temporal; el universo, población y muestra del estudio; unidad de análisis del estudio; las técnicas de recolección de datos e instrumentos. Se desarrolló el diseño del viscosímetro de acuerdo con la norma ASTM D3835, utilizándose el programa de diseño mecánico, AUTODESK INVENTOR PROFESSIONAL y para el diseño del mando y la fuerza de la energía eléctrica se utilizó el software CAD e-SIMU. Como resultado se obtuvieron 12 planos en el Sistema ISO E, donde el undécimo plano corresponde al de ensamblado, es el de mayor importancia porque es allí donde se indica el montaje de las piezas diseñadas y el duodécimo plano es el explosionado de las piezas y partes, donde se muestran todos los componentes del viscosímetro, considerando su orden de montaje y desmontaje. Luego se analizaron dichos resultados con los ajustes debidos del diseño, tomando en consideración los cálculos de estudios de Ingeniería tanto para el diseño de la estructura, elección de partes que conforman el equipo propuesto y los cálculos para el montaje correspondiente. Para la validación del diseño del viscosímetro se acepta el 3% de error respecto a la comparación realizada con un viscosímetro análogo rotacional, Modelo NDJ4, tipo “A” y se llegó a la conclusión que el viscosímetro diseñado se encuentra dentro de los parámetros de aceptación.
Diseño y construcción de un evaporador para la producción de manjar de leche: Aportes a la investigación en Ingeniería
Authors: León Cueva Wilson Patricio , Montaguano Jiménez Jessica Elizabeth , Carrion Espinosa Wilson Emmanuel , Hurtado González Jerling Samantha , Gadvay Yambay Katty Alexandra
Published: July 2024

En el presente proyecto se realizó el diseño y la construcción de un evaporador de simple efecto con chaqueta, destinado a la elaboración de manjar de leche. El proceso de diseño comprendió una revisión exhaustiva bibliográfica y experimentos anteriores, lo cual posibilitó la aplicación de los principios fundamentales de diseño e ingeniería de procesos. De esta manera, se garantizó la precisión en el dimensionamiento y la construcción del equipo requerido para su óptimo rendimiento.

El evaporador consta de 2 cilindros uno interno donde se almacena la materia prima para el proceso y el otro la chaqueta cilindrica recta, en el cual se inyecta vapor proveniente de la caldera que funciona con combustible (diesel), asi mismo el equipo posee un sistema de agitacion con paletas huecas para dar homogenidad al producto durante el proceso cuenta con las debidas valvulas controladoras de vapor, manometro, trampa de vapor en este caso de balde invertido para poder drenar el condensado que se produce dentro de la chaqueta.

Los materiales que se utilizaron en el equipo previo a la construcción fueron láminas, tubos, y varillas de acero inoxidable AISI 304 debidamente cortadas y soldadas. Una de las principales características de este diseño es que se adapta a cualquier tipo de instalación, su fácil ensamblaje y mantenimiento permite un buen funcionamiento del equipo, ya que en su exterior se encuentra una trasferencia de calor necesaria para estar en contacto con la materia prima. El equipo permite la elaboracion de manjar de leche, asi mismo se puede emplear para elaborar pastas, jugos concentrados, leches evaporadas etc, solo hay que tener en cuenta la variables de operación como tiempo, presion y temperatura.
КОЗАЦЬКА ТЕМАТИКА В ТВОРЧОСТІ ТИМОША ПАДУРИ / COSSACK THEMES IN THE WORKS OF TYMOSH PADURA
Authors: Shcherbak Vitalii ,   Borys Grinchenko Kyiv University
Published: July 2024

У статті висвітлено образ козацької України XVI-XVIII ст. у творчій спадщині польського поета і письменника Томаша Падури. Вказано на джерела, які він використовував, та реалії сучасної йому епохи. У творах автора відображені яскраві події та явища козацької доби: лицарський дух запорожців, спільні перемоги українців і поляків над зовнішніми ворогами. Проте, проголошуючи ідею польсько-українського єднання, Падура оминав конфліктні сторінки в їх минулому, прагнув, насамперед, залучити український народ до боротьби за польську справу – визволення з-під російського імперського гніту. Таким чином етнічне походження Тимоша Падури вплинуло на об’єктивне сприйняття і висвітленням минулого України.
ТВОРЧІСТЬ Т. ПАДУРИ В КРИТИЧНІЙ РЕЦЕПЦІЇ В. ГНАТЮКА / THE WORK OF T. PADURA IN THE CRITICAL RECEPTION OF V. HNATIUK
Authors: Nazarets Vitalii ,   Kremenets Taras Shevchenko Regional Academy of Humanities and Pedagogy
Published: July 2024

У запропонованій статті констатовано, що поряд з численними українськими та польськими дослідниками ХІХ-ХХ ст. чи не найбільш вагомим у низці наукових праць вченихфілологів став внесок, який зробив у вивчення літературно-історичних аспектів діяльності «української школи» польського романтизму у цілому й творчості її визначного представника – Т. Падури зокрема, відомий український науковець Володимир Гнатюк. Метою запропонованої розвідки є спроба висвітлення різноаспектних векторів творчості Т. Падури в критичних рецепціях В. Гнатюка. Завданнями, що деталізують наголошену мету, є систематизація та узагальнення: 1) основних етапів наукової діяльності В. Гнатюка, 2) внеску вченого у розвиток української полоністики, 3) основних напрямів дослідження В. Гнатюком творчості Т. Падури. У загальному діапазоні векторів дослідницького інтересу з боку В. Гнатюка до творчості Т. Падури виокремлено такі основні тематичні напрями: 1) Біографічний нарис етапів життєвого шляху Т. Падури, 2) Світоглядні орієнтири письменника, 3) Українське національне питання в творчості Т. Падури, 4) Ідейно-тематичні аспекти творчості, 5) Художні особливості поезії.