bluuebunny/crossref_metadata_2025 huggingface dataset:
THERMAL VARIATION OF THE DIFFERENT LAYERS FORTARFAYA DEPOSIT (MOROCCO) IN HYDRODESULPHURIZATION AS WELL AS HYDROGENATION OF CALCIUM Α, ꞵAND MAGNESIUM AT 550°C AND 750°C.
Authors:   Department of Chemistry, Faculty of Sciences Ben msik Casablanca, University Hassan II Morocco., Nadif Meryem , Attaoui Abdeljabbar ,   Department of Chemistry, Faculty of Sciences Ben msik Casablanca, University Hassan II Morocco.
Published: December 2022

Hydrodesulphurization (HDS), deuteriodesulphurisation, calcium hydrogenation and deuterium treatment are reactions that occur simultaneously when oil shales are treated with hydrogen. In this work, quantitative monitoring of the target elements (sulphur, calcium and magnesium) was carried out using the dispersive X-ray diffraction technique (a technique coupled with a scanning electron microscope). The treatment of oil shale with hydrogen with the objective, either to improve the products preventing oil shale (gas, oil and solid fuel) or in the particular sense to get rid of some undesirable elements having harmful effects on the course of the exploitations of materials we quote the phenomenon of corrosion. An example of this is hydrodesulphurization, which is a reaction that is used to remove sulphur. This hydrogenation reaction was followed in a first work for the different oil shale layers of Tarfaya (M. Hafid and A.Attaoui: 2022) at a temperature of 550Â°C. However we were able to raise the temperature to 750Â°C for this study, in the same sense of the continuity of the action by hydrogen on elements such as calcium and magnesium in the temperature domains this study has been continued.
THE NEED FOR HERBOVIGILANCE
Authors:   Professor and Head, Department of Pharmacognosy & Phytochemistry, PPG College of Pharmacy, Saravanampatti, Coimbatore, Tamilnadu, India-641035., C. Divakar Madhu
Published: December 2022

Objective: This communication outlines herbal drug safety, interactions between herbals and modern medicines, and factors that contribute to herb-drug interactions, including pharmacodynamic and pharmacokinetic interactions and their mechanisms. Methods: The study reviewed the various factors influencing the present pharmacovigilance system in comparison with the herbs related parameters, identified the advantages and disadvantage of the present system and derived modifications which are relevant to herbal drugs safety, efficacy and quality. Conclusion: The present pharmacovigilance system, being structured dominantlyfor modern medicines, needs to be reoriented to include detailed differences of herbal drugs with the former. Major limiting factors include suboptimal compilation of clinically relevant Herb-Drug interactions (HDIs), scarce reporting from patients and the failure to promptly recognized HDIs by health sector providers.A well-documented HDI-database prepared from appropriate case reports can detect ADR signals effectively.
SOLUTIONS TO POSITION-BASED DEVELOPMENT OF A CONTINGENT OF VIETNAMESE HIGH-SCHOOL ADMINISTRATORS
Authors:   Department of Education and Training Nghe An, VietNam., Van Thanh Thai , Van Khoa Nguyen ,   Department of Education and Training Nghe An, VietNam.
Published: December 2022

Through clarifying the role of the key high-school administrators, this article proposed five solutions to the job position-based development of the key high-school administrators below: Developing a master plan for key high-school administrators by local high-school education development Recruiting and employing key-high school administrators who meet the job requirements Holding position-based professional training courses for key high-school administrators Assessing key high-school administrators using position-based competency framework Creating a favorable environment for key high-school administrators to promote and develop their leadership and school administration competencies.
Competition and efficiency in an oligopolistic audit market: Evidence from the Nigerian banking industry
Authors: John Ayoola Tajudeen , Godwin Inneh Eghosa , Ogechukwu Obokoh Lawrence , Ebunoluwa Kolawole Peace , Tokunbo Adeoye Ebunoluwa
Published: December 2022

Economic theory posits that competition drives efficiency; the extent to which this is true in an oligopolistic audit market poses an empirical challenge. Furthermore, studies have postulated that both traditional and modern industrial organization theories are relevant for analyzing market competition. Therefore, this study investigated the effects of static and dynamic audit market competition on audit efficiency in the Nigerian banking industry. Secondary data were obtained from the audited annual financial statements of 12 banks from 2006 to 2020. The study adopted a 2-stage regression model; in the first stage, the audit efficiency scores were derived from an output-based, variable-return-to-scale version of data envelopment analysis (DEA) comprising audit report lag and audit fees as audit input variables and audit quality as the audit output variable. The efficiency scores were regressed on audit market competition and some control variables in the second stage via the bootstrapped truncated regression technique to analyze the effect of competition on efficiency in the audit market. The results showed a positive association between static competition and audit efficiency (50.57, p = 0.014). Because high concentration implied low competition, this finding implied that efficiency was impaired because of a lack of significant competition. The results also showed a positive and significant association between dynamic competition and efficiency, which implied that dynamic competition enhanced efficiency (0.21, p = 0.000) in the audit market. The study concluded that static competition impairs efficiency, while dynamic competition ensures efficiency in the Nigerian banking industry.
Pathophysiology of Type 2 Diabetes: A General Overview of Glucose and Insulin Homeostasis
Authors: Ghasemi Asghar , Kashfi Khosrow
Published: December 2022

The prevalence of diabetes is increasing worldwide, and this disease has a
tremendous financial burden on most countries. Major types of diabetes are type 1
diabetes and type 2 diabetes (T2D); T2D accounts for 90-95% of all diabetic cases. For
better management of diabetes, we need to have a better understanding of its
pathophysiology. This chapter provides an overview of glucose homeostasis and the
underlying pathophysiology of T2D.
Role of Nitric Oxide in Type 2 Diabetes-Induced Osteoporosis
Authors: Yousefzadeh Nasibeh , Jeddi Sajad , Kashfi Khosrow , Ghasemi Asghar
Published: December 2022

Osteoporosis affects 200 million people worldwide. Osteoporosis in subjects with diabetes is called diabetoporosis, and type 2 diabetes (T2D) contributes to and aggravates osteoporotic fractures. Hyperglycemia, insulin resistance, bone vasculature impairment, increased inflammation, oxidative stress, and bone marrow adiposity contribute to a higher incidence of osteoporotic fractures in T2D. Decreased nitric oxide (NO) bioavailability due to lower endothelial NO synthase (eNOS)-derived NO and higher inducible NOS (iNOS)-derived NO is one of the main mechanisms of the diabetoporosis. Available data indicates that T2D increases osteoclast-mediated bone resorption and decreases osteoblast-mediated bone formation, mediated in part by reducing eNOS-derived NO and increasing iNOS-derived NO. NO donors delay osteoporosis and decrease osteoporotic fractures in subjects with T2D, suggesting the potential therapeutic implication of NO-based interventions for diabetoporosis.
Brain Insulin Resistance, Nitric Oxide and Alzheimer’s Disease Pathology
Authors: Pei Zhe , Lee Kuo-Chieh , Khan Amber , Wang Hoau-Yan
Published: December 2022

Alzheimer’s disease (AD) is a devastating age-related neurodegenerative disease characterized by progressive pathological changes and functional and cognitive impairments. Brain insulin resistance appears to contribute significantly to the pathology and cognitive deficits among several pathological mechanisms. Brain insulin resistance has been demonstrated in animal models of AD and postmortem human brain tissue from patients with AD dementia. Studies conducted in AD models and humans suggest attenuating brain insulin resistance by agents such as glucagon-like peptide1 (GLP-1) analogs and small molecule drug candidate PTI-125 reduces many AD pathologic features and symptoms. Insulin affects NO levels by activating endothelial and neuronal nitric oxide synthase (eNOS, nNOS), and systemic insulin resistance has been linked to reduced nitric oxide (NO) bioavailability. Increasing NO availability reduces systemic insulin resistance, and the insulin signaling pathway is associated with the activation of eNOS, implying a causal relationship. This chapter explores this relationship and the role of impaired NO availability in brain insulin resistance in AD dementia.
influence of net working capital and capital structure on profitability in manufacturing companies in the consumer goods industry sector listed on the Indonesia stock exchange
Authors: Putri Dessy Rachma , Isnurhadi Isnurhadi , Widiyanti Marlina , Adam Mohamad
Published: December 2022

The manufacturing industry sector in the goods and consumption sub-sector has an attraction for investors to invest in companies so that to increase the profitability value of the company, several indications are needed to achieve the goal by maintaining the company's assets and assets and always paying attention to the company's debt and equity finance. This study examines 15 food and beverage sub-sector manufacturing companies listed on the Indonesia Stock Exchange (IDX) in 2016-2021, using panel data regression analysis techniques that are time series and cross section to examine the relationship between model variables. The results of the analysis study were obtained where the selection of the Chow test model obtained the Common Effect Model (CEM) selection, while the Hausman test had doubtful results and the Langrange Multiplier test selected the Common Effect Model (CEM) model, while from the estimation results of panel regression data using the option Common Effect Model in which the variables Net Working Capital (0.013) and debt to equity ratio (DER) (0.000) have a positive influence while the debt to asset ratio (DAR) (0.003) has a significant negative effect. -variable with value (10.84 > 3.29).
reality of fostering stress coping skills for lay Buddhists in Hanoi
Authors: Phuong Thich Thanh , Tinh Nguyen Thi , Thuy Hoang Thanh
Published: December 2022

In reality, in Vietnam, to relieve stress, many people choose to go to the temple to balance life and reduce stress. Religious belief is seen as a means to help them transform their body and mind for peace in life. Therefore, temples in Hanoi have organized many activities to help lay Buddhists have skills to cope with stress. This study aims to find out about activities to foster stress coping skills for Lay Buddhists in Hanoi. The research method includes survey and interview. Research results show that activities to foster stress coping skills for Lay Buddhists (aged 18-25) have been interested by local authorities, social organizations, and pagodas. useful activities to contribute to improving the psychological and spiritual quality of Lay Buddhists.
Import of Agricultural Products in the Intra-Regional Comprehensive Economic Partnership (RCEP)
Authors: Simanullang Endang , Hakim Dedi , Syaukat Yusman , Widyastutik Widyastutik
Published: December 2022

The flow of agricultural products through imports has the potential to increase with the geographical conditions of adjacent RCEP countries. Economic and non-economic factors can affect imports of agricultural products. This study aims to analyze the spatial effect and the factors that influence the import of agricultural products in Intra RCEP. This study uses a data period from 2013-2019. The analytical method used in this research is Moran's global index, Local Indicator of Spatial Autocorrelation (LISA), and Geographically Weighted Panel Regression (GWPR). The results show a spatial effect of imports of agricultural products in intra-RCEP. China, Japan, and South Korea are countries that are geographically concentrated in importing agricultural products within the intra-RCEP. The factors that significantly affect the total value of imports of agricultural products are GDP per capita, trade openness, Foreign Direct Investment (FDI), and government effectiveness. The policy recommendations in this study are implementing the RCEP agreement in the long term, open market access, encouraging increased investment in the agricultural sector, and an efficient bureaucracy.
Effect of Simvastatin on Eosinophilic Inflammation of Bladder Tissue in Interstitial Cystitis Rat Model
Authors: Yusuf Muhamad Nur Syukriani , Hasanuddin Abdi Dzul Ikram , Yusuf Zuhriana K , Tuna Trinny , Ibrahim Nurani , Posumah Marshanda Tiara , Tianggara Ridho
Published: December 2022

In the urogenital system, simvastatin is associated with interstitial cystitis adverse effects, but the exact mechanism is not yet clearly defined. This study aims to determine the effect of simvastatin on eosinophilic inflammation of bladder tissue in vivo. Laboratory experimental research design with the post-test only control group using 24 female Wistar rats aged 8-10 weeks were randomly divided into simvastatin 50mg/kg BW (n=12) or placebo carboxymethylcellulose 0.5% (n=12). All groups received treatment through oral gavage for thirty days. After that, each group was divided equally into three subgroups: control rat, day 0 Interstitial Cystitis (IC) rat (IC0), and day 3 IC rat (IC3). Control or IC0 rats each received intravesical instillation of buffered saline or protamine sulfate (PS), respectively, and were terminated immediately less than 3 hours after instillation. The IC3 rats received intravesical PS instillation and were terminated three days post-instillation. The bladder tissue was made in Hematoxylin-Eosin histology preparations. As in previous studies, the results showed successful desquamation of the urothelium after PS instillation. Tissue eosinophil counts were significantly higher in the simvastatin group than in the placebo group in the IC3 model (15.50±5.92 vs. 4.00±2.83, p=0.013). It can be concluded that the mechanism of the adverse effect of simvastatin on bladder tissue is through increased tissue inflammation mediated by eosinophils along with urothelial layer destruction by the protamine sulfate.
Kebijakan Inovatif Tata Kelola Air Bersih Desa melalui Dinamika Tipologi Kelembagaan
Authors: Rifandini Rahmalia
Published: December 2022

Tulisan ini membahas sistem pengelolaan air bersih Desa Suntenjaya di kawasan hulu DAS Cikapundung di Kabupaten Bandung Barat dengan menggunakan kerangka new institutionalism in economic sociology. Studi-studi sebelumnya tentang desa yang memiliki potensi mata air hanya menempatkan perhatian pada perbaikan formalitas lembaga, khususnya pada optimalisasi peran pemerintah desa dan BUMDes dalam mekanisme Pengelolaan Air Bersih (PAB). Studi-studi ini belum menganalisa insentif dan hambatan pada tata kelola air di luar institusi formal. Padahal, institusi informal juga berperan besar dalam PAB. Untuk menutupi kekurangan tersebut, penelitian ini mengadaptasi tipologi Helmke-Levitsky untuk mengidentifikasi interaksi antara kelembagaan formal desa dengan kelembagaan informal-lokal ulu-ulu dalam tata kelola air bersih desa. Secara metode, penelitian ini menyajikan keterbaruan berupa pengaplikasian software digital untuk proses koding wawancara dengan menggunakan QDA Miner. Berdasarkan temuan penelitian ini, kelembagaan informal-lokal ulu-ulu telah berperan sebagai substitusi kelembagaan formal desa. Lemahnya kapasitas kelembagaan formal di tengah adanya kebutuhan masyarakat terhadap sistem pengelolaan air bersih memunculkan peran ulu-ulu untuk menjawab permasalahan tersebut melalui pengelolaan air bersih desa berdasarkan hak asal-usul desa.
An Unusual Presentation of “Two-Thirds Tumor” in the Mandible – A Diagnostic Quandary with a Review of the Literature
Authors: T Jayapriya , Patil Namratha , Keluskar Vaishali , M Sridhar , S Lokesh Kumar , Panwar Arun
Published: December 2022

An adenomatoid odontogenic tumor (AOT) is an uncommon benign tumor of the oral cavity commonly found in the maxillary anterior region and is associated with impacted canines in young females. It rarely occurs in the mandibular region with no impacted or missing teeth. A 21-year-old female reported to the clinic with swelling on the right side of the face for the past six months with no history of pain. Radiographic features such as unilocular radiolucency with thinning of the cortical borders and considerable buccal cortical expansion, as well as some evidence of radiopaque specks were noted. Histopathological examination revealed cells with hyperchromatic nuclei, rosette-like structures with focal areas of calcified mass, and concentric rings resembling Liesegang rings, suggestive of AOT. The tumor was treated surgically by enucleation and cauterization. Although follicular type is a common variant, the tumor presented in this case was of extrafollicular type noted in the mandibular canine and premolar regions of a young female patient with no related impacted tooth.
EFEK GENDER, KESULITAN AKUNTANSI, PELUANG KARIR DAN SINDROM IMPOSTOR TERHADAP KEPUTUSAN MAHASISWA MEMILIH JURUSAN AKUNTANSI
Authors: Soedradjat Sabrina Berliani , Suryaningrum Diah Hari
Published: December 2022

Penelitian ini bertujuan melihat serta membuktikan adanya efek dari gender, kesulitan akuntansi, peluang karir dan fenomena sindrom impostor terhadap keputusan mahasiswa dalam memilih jurusan akuntansi PTN atau PTS di Surabaya. Penelitian ini menggunakan metode kuantitatif memakai sumber data primer yang didapatkan dari menyebar kuesioner. Populasi penelitian ini merupakan mahasiswa akuntansi dan manajemen program S1 angkatan 2018 di Perguruan Tinggi Negeri Surabaya (UPN Veteran Jawa Timur) dan Perguruan Tinggi Swasta Surabaya (Universitas Surabaya). Pengambilan sampel dihitung memakai persamaan slovin diperoleh sampel 291 mahasiswa. Cara pemilihan sampel memakai purposive sampling. Teknik yang dipakai untuk analisis data ialah regresi logistic yang dihitung memakai SPSS 25.0 for windows. Hasil penelitian ini menunjukkan bahwa peluang karir berdampak positif bagi keputusan mahasiswa dalam menentukan jurusan akuntansi, sedangkan gender, kesulitan akuntansi dan fenomena sindrom impostor berdampak negatif bagi keputusan mahasiswa dalam menentukan jurusan akuntansiKata Kunci: Gender, Kesulitan akuntansi, Peluang Karir, Sindrom impostor, Akuntansi.
EVALUASI KINERJA PERUSAHAAN SELAMA PANDEMI COVID-19 MELALUI PENDEKATAN ECONOMIC VALUE ADDED (EVA) DAN MARKET VALUE ADDED (MVA) DENGAN TIME SERIES APPROACH (Studi pada Perusahaan LQ45 Sub Sektor Property and Real Estate yang Terdaftar di Bursa Efek Indonesia Periode Tahun 2019 - 2020)
Authors: Kusumastuti Anggit Dyah , Mutiasari Annisa Indah , Paningrum Destina
Published: December 2022

Economic Value Added (EVA) dan Market Value Added (MVA) merupakan metode baru mengukur kinerja perusahaan yang mendasarkan pada nilai. Pendekatan Economic Value Added (EVA) dan Market Value Added (MVA) dengan time series approach merupakan alat ukur kinerja keuangan untuk melihat sejauh mana efektivitas perusahaan dalam pengembalian atas investasi melalui ukuran kinerja yang dilihat dari nilai tambah (value based). Penelitian ini bertujuan mengetahui kinerja perusahaan Property and Real Estate yang masuk dalam LQ45 yang terdaftar di Bursa Efek Indonesia (BEI) selama pandemi covid-19 tahun 2019-2020 dengan pendekatan Economic Value Added (EVA) dan Market Value Added (MVA) dengan time series approach. Hasil penelitian menunjukkan perusahaan Bumi Serpong Damai Tbk, Ciputra Development Tbk, menghasilkan nilai EVA di bawah rata-rata industri, sedangkan Pakuwon Jati, Tbk menghasilkan nilai EVA di atas rata-rata industri. Nilai MVA untuk perusahaan Bumi Serpong Damai, Tbk dan Ciputra Development, Tbk menghasilkan nilai di atas rata-rata industri, sedangkan Pakuwon Jati, Tbk dengan nilai MVA di bawah rata-rata industri. Rata-rata penilaian Economic Value Added (EVA) dan Market Value Added (MVA) sebesar 383 menunjukkan nilai positif. Hal ini menunjukkan bahwa kondisi sektor property and real estate secara keseluruhan berkinerja baik. Dengan mengetahui nilai EVA dan MVA mengidentifikasikan perusahaan mampu meningkatkan kinerja melalui keputusan investasi dan esejahteraan investor. Kata kunci : Economic Value Added (EVA), Market Value Added (MVA), Kinerja Perusahaan Property and Real Estate, Covid-19
Health Promotion in Popular Web-Based Community Games Among Young People: Proposals, Recommendations, and Applications
Authors: Martin Philippe , Chapoton Boris , Bourmaud Aurélie , Dumas Agnès , Kivits Joëlle , Eyraud Clara , Dubois Capucine , Alberti Corinne , Le Roux Enora
Published: December 2022

Background

Young people use digital technology on a daily basis and enjoy web-based games that promote social interactions among peers. These interactions in web-based communities can develop social knowledge and life skills. Intervening via existing web-based community games represents an innovative opportunity for health promotion interventions.

Objective

The aim of this study was to collect and describe players’ proposals for delivering health promotion through existing web-based community games among young people, elaborate on related recommendations adapted from a concrete experience of intervention research, and describe the application of these recommendations in new interventions.

Methods

We implemented a health promotion and prevention intervention via a web-based community game (Habbo; Sulake Oy). During the implementation of the intervention, we conducted an observational qualitative study on young people’s proposals via an intercept web-based focus group. We asked 22 young participants (3 groups in total) for their proposals about the best ways to carry out a health intervention in this context. First, using verbatim transcriptions of the players’ proposals, we conducted a qualitative thematic analysis. Second, we elaborated on recommendations for action development and implementation based on our experiences and work with a multidisciplinary consortium of experts. Third, we applied these recommendations in new interventions and described their application.

Results

A thematic analysis of the participants’ proposals revealed 3 main themes and 14 subthemes related to their proposals and process elements: the conditions for developing an attractive intervention within a game, the value of involving peers in developing the intervention, and the ways to mobilize and monitor gamers’ participation. These proposals emphasized the importance of interventions involving and moderating a small group of players in a playful manner but with professional aspects. We established 16 domains with 27 recommendations for preparing an intervention and implementing it in web-based games by adopting the codes of game culture. The application of the recommendations showed their usefulness and that it was possible to make adapted and diverse interventions in the game.

Conclusions

Integrated health promotion interventions in existing web-based community games have the potential for promoting the health and well-being of young people. There is a need to incorporate specific key aspects of the games and gaming community recommendations, from conception to implementation, to maximize the relevance, acceptability, and feasibility of the interventions integrated in current digital practices.

Trial Registration

ClinicalTrials.gov NCT04888208; https://clinicaltrials.gov/ct2/show/NCT04888208
Physical education curricula and teaching methodologies for special needs learners: a protocol for a scoping review (Preprint)
Authors: Mc Creanor Xavier , Naidoo Rowena , Chetty Verusia
Published: December 2022

BACKGROUND

Learners with special needs around the world, including in South Africa, are included in mainstream schools. However, it has been reported that learners experience exclusion and a lack of belonging in physical education classes. There is great concern about the lack of training teachers should undergo to teach physical education to special needs learners. The current public school physical education systems face difficulties in the delivery of quality physical education to special needs learners. Physical education classes need to be adapted to suit the individual needs of every special need learner.

OBJECTIVE

Learners with special needs around the world, including in South Africa, are included in mainstream schools. However, it has been reported that learners experience exclusion and a lack of belonging in physical education classes. There is great concern about the lack of training teachers should undergo to teach physical education to special needs learners. The current public school physical education systems face difficulties in the delivery of quality physical education to special needs learners. Physical education classes need to be adapted to suit the individual needs of every special need learner.

METHODS

By conducting a scoping review, a literature search in the following electronic databases: Google Scholar; EBSCOhost; the Cochrane Library; PubMed; and Science Direct will be used. The research team will also conduct a reference list search to ensure that all relevant articles are included in the study. The initial phase of the screening process will be carried out by two researchers. Thereafter, the researchers will use the expertise of a fellow researcher to collaboratively abstract the data, organise it into themes and sub-themes, summarise them, and report the results in a narrative synthesis.

RESULTS

The evidence gathered in the review will be analysed and discussed in a narrative format. The review will provide insights into the emergent themes in Physical Education for special needs students realm. The review will provide a baseline of evidence on curricula and teaching methodologies to assist teachers teaching PE to special needs learners.

CONCLUSIONS

The final scoping review will aim to not only highlight the gaps in the research regarding curricula and teaching methodologies being used but also to elaborate on the current practices being used. This information will be of great value to fellow researchers and physical education teachers. The information gathered will be used in a broader study to create a physical education toolkit to further assist teachers teaching physical education to special needs learners.

CLINICALTRIAL

Systematic review registration: Open Science Framework (https:// 10.17605/OSF.IO/BXKDR).
Development and Usability Study of the Stance4Health nutritional APP: A Path to Personalized Smart Nutrition (Preprint)
Authors: Hiinojosa-Nogueira Daniel , Ortiz-Viso Bartolomé , Navajas-Porras Beatriz , Pérez-Burillo Sergio , González-Vigil Verónica , Pastoriza Silvia , Rufián-Henares José A.
Published: December 2022

BACKGROUND

Due to its influence on health, access to a good diet is one of the great objectives of the health services in many countries. There are many electronic services that offer advice on diet, recommending specific foods or recipes. Additionally, as information processing techniques advance, options to tackle a multi-factorial and individualized nutritional recommendation also increase in number, allowing the recommendation of complete menus taking into account several parameters.

OBJECTIVE

In this article we present and validate a personalized nutrition system based on an application (APP) for smart devices with the capacity to offer an adaptable menu to the user.

METHODS

The APP was developed following a structured recommendation generation scheme, where the characteristics of the menus of 20 users were evaluated. From these, a user profile was developed with their nutritional requirements and menus were generated for 2 weeks. These menus were evaluated by comparing their mean nutritional content versus the mean nutrient composition retrieved from dietary records.

RESULTS

The generated menus showed great similarity to those obtained from the user dietary questionnaires. However, the generated menus showed less variability regarding the amounts of micronutrients reached. This lower variability was accompanied by higher quantities of most of the micronutrients tested in the user menus. The macronutrient deviations were also corrected in the generated menus, offering a better adaptation to the biometric parameters provided by the users.

CONCLUSIONS

The presented system is a good tool for the generation of menus that are adapted to the user characteristics. It is therefore a starting point to carry out nutritional interventions where it is necessary to control the amount of nutrients. These nutritional interventions will be important to validate other modules of the system.

CLINICALTRIAL

ISRCTN63745549

INTERNATIONAL REGISTERED REPORT

RR2-https:// doi.org/10.3390/foods11101480
Mindfulness-Based Mobile Apps and Their Impact on Well-Being in Nonclinical Populations: Systematic Review of Randomized Controlled Trials (Preprint)
Authors: Schwartz Katrin , Ganster Fabienne Marie , Tran Ulrich S
Published: December 2022

BACKGROUND

Mindfulness-based mobile apps have become popular tools for enhancing well-being in today’s fast-paced world. Their ability to reduce geographical, financial, and social barriers makes them a promising alternative to traditional interventions.

OBJECTIVE

As most available apps lack a theoretical framework, this review aimed to evaluate their effectiveness and assess their quality. We expected to find small sample sizes, high dropout rates, and small effect sizes in the included studies.

METHODS

A systematic literature search was conducted using PsycInfo, PsycNet, PubMed, an institutional search engine (u:search), and Google Scholar. Randomized controlled trials assessing the impact of mobile mindfulness apps on well-being in nonclinical samples were included. Study selection, risk of bias (using the version 2 of the Cochrane risk-of-bias tool for randomized trials), and reporting quality (using selected CONSORT [Consolidated Standards of Reporting Trials] statement criteria) assessments were performed by 2 authors independently and discussed until a consensus was reached.

RESULTS

The 28 included randomized controlled trials differed in well-being measures, apps, and intervention duration (7 to 56 days; median duration 28 days). A wide range of sample sizes (12 to 2282; median 161) and attrition rates (0% to 84.7%; median rate 23.4%) were observed. Most studies (19/28, 68%) reported positive effects on at least one aspect of well-being. The effects were presented using different metrics but were primarily small or small to medium in size. Overall risk of bias was mostly high.

CONCLUSIONS

The wide range of sample sizes, attrition rates, and intervention periods and the variation in well-being measures and mobile apps contributed to the limited comparability of the studies. Although most studies (16/28, 57%) reported small or small to medium effects for at least one well-being outcome, this review demonstrates that the generalizability of the results is limited. Further research is needed to obtain more consistent conclusions regarding the impact of mindfulness-based mobile apps on well-being in nonclinical populations.
Branding dan Promosi Kawasan Wisata Pesisir Pesona Desa Gisik Cemandi
Authors: Banu Prasetyo  , Edy Subali  , Enie Hendrajati  , Umi Trisyanti  , Sukriyah Kustanti Moerad  , Wahyuddin
Published: December 2022

Gisik Cemandi is a village that manages with community-based. Therefore, the types of tourism that have the most potential to be developed are religious tourism and marine tourism. Unfortunately, Gisik Cemandi is still constrained in the development of tourism from year to year due to the lack of community expertise in branding, promotion, and mapping of economic potential in the development of marine tourism. Seeing this opportunity, the ITS Development Studies Department has assisted in branding activities and promoting marine tourism in Gisik Cemandi. The community service program includes branding counselling for marine tourism for two months. The purpose of this service is for Gisik Cemandi Village to have its trademark so that tourists easily recognize it. Furthermore, the Team will promote social media to attract tourists to travel to Gisik Cemandi Village. The result of this community service is the video promotion profile of Gisik Cemandi and the logo of Pesona Bahari as a trademark of Gisik Cemandi.

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Desa Gisik Cemandi merupakan desa dengan kategori desa swasembada. Jenis-jenis wisata yang paling berpotensi untuk dikembangkan di desa ini adalah wisata religi dan wisata bahari. Namun, dari tahun ke tahun, Desa Gisik Cemandi masih terkendala dalam pengembangan wisata tersebut karena kurangnya keahlian masyarakat dalam melakukan branding, promosi, pemetaan potensial ekonomi dalam pengembangan wisata bahari. Melihat peluang tersebut, Tim Pengabdian Departemen Studi Pembangunan ITS telah melakukan pengabdian dalam bentuk pendampingan terhadap kegiatan branding dan promosi wisata bahari di Desa Gisik

Cemandi. Kegiatan pengabdian ini meliputi penyuluhan branding Desa Wisata Bahari selama dua bulan. Kegiatan pengabdian ini bertujuan agar Desa Gisik Cemandi memiliki trademarknya sendiri sehingga mudah dikenal oleh para wisatawan. Selanjutnya, Tim Pengabdian akan melakukan promosi melalui media sosial untuk menarik wisatawan agar berwisata di Desa Gisik Cemandi. Hasil dari pengabdian ini adalah dihasilkannya

video profile dan logo Pesona Bahari Desa Gisik Cemandi sebagai sarana promosi pariwisata.
Penanaman Pola Pikir Kritis Berwawasan Eco-Pesantren Reduce Reuse dan Recycle di Pondok Modern Tazakka Batang
Authors: Irianti Danika Rahma , Hidayat Ferry , Restu Pandu Wiguna , Sujiwa Krisna , Aris Munandar  , Achmad Munjid  , Amin Basuki
Published: December 2022

One of the Tri Dharma of College institutions is a form of community service. This program aims to provide education and hands-on practice regarding environmental management and procedures for managing waste properly and correctly to fellow students at Pondok Modern Tazakka in Batang district, Central Java. This community service is carried out using a Service-Learning approach. Robert Sigmon (1979), described service-learning as an experiential educational strategy based on “reciprocal learning”. The target of this activity is the students at Pondok Modern Tazakka with a total of 77 people with the result’s hope that they can understand how to manage waste properly, especially in the living environment so that it would not create a further environmental problem. This activity uses the form of seminar and direct practice in the form of making mind mapping about their creative ideas on how to manage waste, this activity runs smoothly and it is very visible through the enthusiasm of the students engaged in each of the agendas. The results of this activity are hoped that the students can directly practice the knowledge gained from educational activities on waste management and the environment.

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Salah satu Tri Dharma Perguruan Tinggi adalah adanya kegiatan pengabdian masyarakat. Program ini bertujuan untuk memberikan edukasi dan praktik langsung mengenai pengelolaan lingkungan dan tata cara mengelola sampah yang baik dan benar kepada para santriwan di Pondok Modern Tazakka di Kabupaten Batang, Jawa Tengah. Kegiatan pengabdian ini dilaksanakan dengan pendekatan Service-Learning. Robert Sigmon (1979) menggambarkan Service-Learning sebagai strategi pendidikan pengalaman berdasarkan “Reciprocal Learning”. Sasaran kegiatan ini adalah sejumlah 77 orang santriwan Pondok Modern Tazakka, dengan harapan mereka bisa memahami cara mengelola sampah, khususnya di lingkungan tempat tinggal mereka, agar tidak menimbulkan masalah lingkungan. Kegiatan dilaksanakan melalui seminar dan praktik secara langsung, yang berupa pembuatan mind mapping tentang ide-ide kreatif cara pengelolaan sampah. Kegiatan ini berjalan dengan lancar dan sangat terlihat antusiasme dari para santriwan saat mengikuti setiap acara yang diselenggarakan oleh tim PkM. Melalui kegiatan edukasi ini diharapkan agar para santriwan dapat mempraktikkan ilmu yang diperoleh untuk pengelolaan sampah dan lingkungan.
Peningkatan Resiliensi Badan Usaha Milik Desa Merespon Dampak Pandemi Covid-19
Authors: Hudayana Bambang , Kutanegara Pande Made , Fauzanafi Muhammad Zamzam , Purbawisesa Angie , Rakryan W D Ulhaq
Published: December 2022

The COVID-19 pandemic has impacted the decline in tourism activities, both those managed by companies, individuals, villages, and Village-Owned Enterprises (BUMDes). The decline in tourism activities has had a secondary impact on small-scale businesses related to the tourism sector. The heavy dependence on the tourism sector and limited other business opportunities have hit the tourism industry's economy hard. Therefore, efforts are needed to enable them to survive and rise from the downturn in these activities. As one of the institutions that carry the Tri Darma of Higher Education, the campus world should have moved to carry out community service dharma. With community service, empowerment programs can be carried out for BUMDes and these business actors to increase resilience. The empowerment program is carried out as (1) workshop facilitation support and discussions with BUMDes managers and business actors in mapping problems and (2) formulating an action plan to reduce the impact and economic recovery of the COVID-19 pandemic. This empowerment program succeeded in mapping out problems and action plans to increase economic resilience during a pandemic and economic recovery through developing multiple economic businesses, such as preserving the tourism business while advancing farming, animal husbandry, mushroom cultivation, and herbal home industries.

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Pandemi Covid-19 telah berdampak pada merosotnya aktivitas pariwisata baik yang dikelola oleh perusahan, perorangan, desa dan juga Badan Usaha Milik Desa (BUMDes). Kemerosotan kegiatan pariwisata membawa dampak ikutan terhadap usaha skala kecil yang terkait dengan sektor pariwisata. Ketergantungan yang besar terhadap sektor pariwisata dan keterbatasan peluang usaha lain telah memukul perekonomian pelaku wisata secara telak. Oleh karena itu, diperlukan upaya-upaya yang memungkinkan mereka tetap survive dan bangkit dari keterpurukan aktivitas tersebut. Dunia kampus sebagai salah satu institusi yang mengusung Tri Darma Perguruan tinggi sudah semestinya bergerak untuk melakukan darma pengabdian kepada masyarakat. Dengan pengabdian pada masyarakat dapat dilaksanakan program pemberdayaan bagi BUMDes dan pelaku usaha tersebut agar dapat meningkatkan resiliensi. Program pemberdayaan dilakukan dalam bentuk dukungan fasilitasi workshop dan diskusi pengelola BUMDes dan pelaku usaha dalam melakukan pemetaan masalah, dan perumusan rencana aksi untuk mengurangi dampak  dan pemulihan ekonomi pandemi Covid-19. Program pemberdayaan ini berhasil memetakan masalah, dan rencana aksi untuk peningkatan resiliensi ekonomi pada masa pandemi dan pemulihan ekonomi melalui pengembangan usaha ekonomi ganda, seperti melestarikan usaha di pariwisata sambil memajukan usaha tani, peternakan, budidaya jamur dan industri rumah tangga herbal.
Confronting the Constitutional Challenges to Realizing the Right to Development of the Niger Delta Communities in Nigeria
Authors: AJOKU ESQ O. OGECHUKWU
Published: December 2022

This chapter seeks to examine the role of law, legislative, regional and multilateral instruments towards confronting the challenges to realizing the right to development of the Niger Delta communities in Nigeria. Such enabling instrument as African Charter on Human and Peoples’ Rights creates legal obligations for African States to implement the right to development. In other words, legal and constitutional protection of the right to development is very important either directly through the inclusion of the right to development in the constitutional bill of rights, or indirectly by ensuring applicability and justiciability of the African Charter in domestic law. This is a cue for the Nigerian government to follow. Inspite of these enabling instruments, the potential of the right to development in Nigeria remains largely untapped. In Africa, and by extension Nigeria, the right to development enjoys a legal status equal to all other human rights (Note 1). This is due to its inclusion in the African Charter on Human and Peoples’ Rights, though the practice of implementation remains hitherto unexplored, nor its potentials as an instrument to protect the well being of the population exhausted (Note 2). This chapter shall review domestic, regional and global instruments of the right to development, examining the case law of the African commission on Human and Peoples’ Right, as well as the duty of the Nigerian government to take into account the right to development of the Niger Delta in furtherance of their international obligations. The African Charter is an innovative and unique regional document that substantially departs from the narrow formulations of other regional and universal human rights instruments, particularly by the insertion of the group and peoples’ rights (Note 3). This work investigates the challenges and constraints to realizing the right to development of the Niger Delta communities of Nigeria amidst the regional, as well as international instruments that guarantee such a right. By constraints and challenges it is meant problem of constitutionalism that assails the opportunity for the involvement of the people of the Niger Delta in whatever decision that concerns their development and restoration of the environment and ecology. It seeks to situate human beings, rather than growth, at the centre of the development process. (Note 4) The right to development appeared in a number of important soft law instruments such as the World Conference on Human Rights Vienna Declaration, The Millennium Declaration, and the Rio+20 Outcome Document (Note 5). These documents were adopted by consensus, not by split vote, yet provided insufficient evidence of a genuine legal conviction supporting the right to development, nor a move towards law making on the right to development. They are therefore mere recommendations lacking in authentic legal force.
Canvas Methodology Applied in the Development of the Platform for Lending between People for Breweries
Authors: Gonçalves Thalhes Noronha , Santos Weder Ferreira dos , Souza Clóvis Maurilio de , Peluzio Joênes Mucci , Santos Layanni Ferreira Sodré , Cerqueira Fernando Barnabé , Lopes Leonardo Alves , Fidelis Cícero Antônio Sobreira , Dias Vanderlan Carneiro , Maciel Lucas Carneiro , Ribeiro Antônio Henrique Camilo , Fernandes João Victor Rodrigues , Sousa Mateus Lima de
Published: December 2022

The objective of this work presents a business model using the Canvas methodology proposing the creation of a credit and financing platform for breweries. Initially, the main idea was delimited, we sought information, building a chain of authors, articles, and websites concatenated to the theme for immersion and definition of the questions that would integrate each block. The Canvas tool was used in the construction of the business model where each step of the block was filled clarifying what the value proposition was, for whom it would generate, how it would be done and by how much, and thus, presenting the properly completed business model contributing to the empirical prototyping of the business.
GC-MS Analysis and In-vitro Apoptosis Induction and Anticancer Activity of Methanol Extract of Aspergillus terreusagainst Lung Cancer
Authors: Sanjotha G. , Shivasharana C.T. , Shettar Arun K. , Manawadi Sudheer , Devendra B.N.
Published: December 2022

The present study was focusing on qualitative and quantification of bioactive compounds present in Aspergillus terreus and evaluating its anticancer activity and apoptosis detection against lung cancer. Methods: A. terreus was sequentially extracted using the Soxhlet extraction technique with hexane, ethyl acetate, methanol and distilled water. Detection of bioactive compounds was done using Standard biochemical tests and GC-MS analysis was performed with NIST database to identify the bioactive compounds. The toxicity and anticancer activity of crude extract was investigated using MTT assay on L929 cells and lung cancer A549 cells whereas apoptosis study was conducted through Flowcytometry-based surface marker study on the A549 cancer cell line. Results: secondary metabolites analysis showed the presence of phenols and terpenoids as major constituents in the methanol extract whereas other solvent extracts have shown the absence of major bioactive compounds. Quantification studies showed that methanol extract has shown the phenolic content 179 µg/g of Gallic acid equivalent. The GC-MS analysis showed the presence of 1-Flurodecane, Methyl palmitate, Ethyl palmitate, 9, 12-Octadecanopic acid, 10-Octadecanoic acid, Methyl stearate, Octadecadeoinoate, Ethyl 9-hexadecanoate and 1-Monoarachidin as major bioactive compounds. Further, MTT based toxicity study on the L929 cell line revealed that methanol extract at lower concentrations like 50µg, 100µg and150µg shown more than 50% of cell viability and at higher concentration between 200µg-250 µg it was showing toxic nature with 47.89±0.01% viability. In case of anticancer activity against lung cancer A549 cell line the methanol extract have shown the dose dependent activity i.e the percentage of cell viability was decreased with increase in the concentration of methanol extract at 250µg the cell viability was found to be 35.12±0.005%. Flow cytometry based apoptosis study revealed that methanol extract has shown the inducing apoptosis in treated lung cancer A549 cells with percentage of 10.84. Conclusion: overall the present study shown that A. terreus possess different class of bioactive compounds and it has higher phenolic content. Toxicity study showed that methanol extract exhibited toxic nature at higher concentration on tested cell line and Anticancer and Apoptosis study revealed that methanol extract has shown the prominent with inhibiting the growth of lung cancer A549 cells through inducing apoptosis. Further, A. terreus would be a promising natural microorganism that has to be further researched in order to discover and isolate potent drug to treat cancer. Future studies will be on study of in-vivo animal studies and study of molecular mechanism of drug action on particular with anticancer study.
Antimicrobial Property of Cassava Starch/Chitosan Film Incorporated with Lemongrass Essential Oil and Its Shelf Life
Authors: Perdana Muhammad Iqbal , Panphon Somrak , Ruamcharoen Jareerat , Leelakriangsak Montira
Published: December 2022

There has been a spreading attention in the present day to develop environmentally friendly materials such as biodegradable starch films with antimicrobial properties for food protection. Chitosan has exhibited antimicrobial activity against a wide range of microorganisms which provided great potential to be used as a packaging material to prolong the shelf life of food products. The antimicrobial properties of chitosan against some food-borne pathogens were investigated. Chitosan ranging from 2.5 to 10 mg ml-1 against some pathogenic bacteria (Escherichia coli TISTR 512, Bacillus cereus TISTR 035 Staphylococcus aureus TISTR 746 and Salmonella typhimurium TISTR 1470) and yeast (Candida albicans TISTR 5554) was determined. All tested bacteria could be inhibited by concentration of 10 mg ml-1 except C. albicans TISTR 5554. Cassava starch/chitosan films incorporated with lemongrass essential oil were examined in addition to its mechanical properties and antimicrobial stability during storage. Total bacteria and fungi counts were low during 12 weeks of storage and tensile strength decreased after 6 months of storage. However, elongation at break showed no significant difference during the storage process. The functional and structural groups of tested films did not change during 6 months of storage confirmed by fourier transform infrared (FTIR) analysis. Overall, these films have been recognized to be beneficial for application due to its stability, antimicrobial property and biodegradable nature.