bluuebunny/crossref_metadata_2025 huggingface dataset:
Pencegahan Pandemik Covid-19 dengan Hand Sanitizer Prodi Sains UIN Antasari Banjarmasin
Authors: Suryandari Suryandari , Astutik Trining Puji , Istiqamah Istiqamah
Published: July 2022

Pandemik COVID-19 menjadi fokus pemerintah di seluruh dunia karena terhitung sampai dengan 20 Maret 2020 terdapat 271.206 kasus penularan wabah COVID-19 tersebar pada 184 negara. Proteksi awal dari penyebaran virus dengan menjalankan hidup sehat dan bersih serta melakukan self distancing. Salah satu solusi pencegahan virus dibutuhkan cairan pembersih tangan yang efektif dan efisien, yaitu hand sanitizer dan cairan disinfektan khususnya di lingkungan UIN Antasari. Kegiatan pengabdian kepada masyarakat dilakukan melalui empat tahap, yaitu: persiapan, produksi, distribusi, dan kontribusi. Hand sanitizer dan cairan disinfektan dibuat berdasarkan resep BPOM dan Dinas Kesehatan. Kemasan hand sanitizer botol yang digunakan berukuran 100 mL sehingga mudah untuk dibawa. Hand sanitizer dan cairan disinfektan mampu mengupayakan pencegahan pandemik COVID-19 khususnya di lingkungan UIN Antasari, Produk didistribusikan kepada pihak-pihak yang rentan terpapar seperti pada unit. Dosen dan staf, pihak mahasiswa yang aktif (Himpunan Mahasiswa) serta masyarakat di sekitar lingkungan UIN Antasari. The COVID-19 pandemic has become the focus of governments worldwide because, as of March 20, 2020, 271.206 cases of transmission of the COVID-19 outbreak spread over 184 countries. Initial protection from the spread of the virus by living a healthy and clean life and practising self-distancing. One solution to prevent the virus is to use an effective and efficient hand sanitizer, namely hand sanitizer and disinfectant, especially at UIN Antasari. Community service activities are carried out through four stages, namely: preparation, production, distribution, and contribution. Hand sanitizers and disinfectant liquids are made based on a prescription from BPOM and the Health Service. The bottle hand sanitizer packaging used is 100 mL, so it is easy to carry. Hand sanitizers and disinfectant liquids can try to prevent the COVID-19 pandemic, especially in the Antasari UIN environment. Products are distributed to parties who are vulnerable to exposure, such as units: lecturers and staff, active students (Student Association) and the community around UIN Antasari.
Sosialisasi Pentingnya Nilai-nilai Pancasila dan Eksistensinya bagi Mahasiswa
Authors: Saragih Sepriandison
Published: July 2022

Kegiatan sosialisasi ini bertujuan untuk membantu mahasiswa HKBP Nommensen Universitas Pematangsiantar menggunakan dan menyebarluaskan karakter Pancasila dalam kehidupan sehari-hari, karena Pancasila adalah dasar negara Indonesia. Indonesia sendiri merupakan negara multikultural, yang dibuktikan dengan keragaman ras, suku, agama dan budaya. Metode Kegiatan sosialisasi ini di lakukan dengan tiga tahap yaitu adalah penyerahan materi, bagian dari sesi tanya jawab dengan mahasiswa, pembagian hadiah kepada mahasiswa. Hasil dari kegiatan sosialisasi ini adalah banyak adat istiadat yang diungkapkan dalam bahasa Pancasila, yaitu Bhineka Tunggal Ika, memiliki arti yang berbeda tetapi tetap sama. Pancasila sebagai dasar negara harus menjadi ruh budaya individu negara. Dengan mengajarkan karakter Pancasila sejak dini, Indonesia akan kuat dan fleksibel dalam menghadapi kesulitan. Oleh karena itu kesimpulan yang ditarik dan kegiatan sosialisasi ini adalah bahwa Pancasila ingin mencerminkan harkat dan martabat dunia yang dikenal agar dapat diwujudkan dalam kehidupan nyata. Semoga karakter Pancasila ini dapat diterapkan dalam kehidupan sehari-hari. This socialization activity aims to help HKBP Nommensen students at Pematangsiantar University use and disseminate the character of Pancasila in their daily lives because Pancasila is the basis of the Indonesian state. Indonesia is a multicultural country, as evidenced by the diversity of race, ethnicity, religion and culture. Methods: This socialization activity was carried out in three stages: submission of materials, part of a question and answer session with students, and distribution of prizes to students. The result of this socialization activity is that many customs expressed in the language of Pancasila, namely Bhineka Tunggal Ika, have different meanings but remain the same. As the basis of the state, Pancasila must be the individual state's cultural spirit. By teaching the character of Pancasila from an early age, Indonesia will be strong and flexible in facing difficulties. Therefore, the conclusion drawn from this socialization activity is that Pancasila wants to reflect the dignity of the known world so that it can be realized in real life. Hopefully, this Pancasila character can be applied in everyday life.
Pelatihan Pemanfaatan Daun Kelor sebagai Makanan Tambahan Balita Malnutrisi
Authors: Senudin Putriatri Krimasusini , Trisnawati Reineldis E , Janggu Jayanthi P , Mbohong Catrine C. Y
Published: July 2022

Masalah gizi masih menjadi masalah terbesar pada bayi dan balita di Indonesia. Berbagai upaya untuk mengatasi masalah gizi pada balita dengan intervensi gizi spesifik dan intervensi gizi sensitif. Kegiatan pelatihan ini dilakukan sebagai intervensi gizi sensitif dengan memberikan pendidikan melalui pemberdayaan keluarga dalam memanfaatkan daun kelor sebagai makanan tambahan dalam bentuk teh daun kelor. Peserta pelatihan adalah ibu–ibu yang mempunyai bayi dan balita yang mengalami malnutrisi sebanyak 28 orang. Kegiatan ini dilaksanakan pada tanggal 16-17 April 2021 posyandu di wilayah kerja Puskemas Pembantu Tenda secara berkelompok dikarenakan adanya pandemic covid 19. Hasil menunjukkan bahwa terdapat peningkatan pengetahuan peserta pelatihan sebelum dan setelah dilakukan penyuluhan. Kegiatan pengabdian ini dapat bermanfaat dalam meningkatkan pengetahuan dan pemahaman mengenai cara pengolahan daun kelor menjadi teh yang dapat dikonsumsi oleh bayi dan balita. Hal tersebut berperan penting dalam penanggulangan serta pencegahan terhadap masalah malnutrisi pada bayi dan balita sehingga meningkatkan derajat kehidupan masyarakat. Nutritional problems are still the biggest problem in infants and toddlers in Indonesia. Various efforts to overcome nutritional problems in toddlers with specific nutrition interventions and sensitive nutrition interventions. This training activity was carried out as a sensitive nutrition intervention by providing education through empowering families in utilizing Moringa leaves as additional food in the form of Moringa leaf tea. The training participants were 28 mothers with infants and toddlers who were malnourished. This activity was carried out on 16 -17 April 2021 at the Posyandu in the Tent Auxiliary Health Center working area in groups due to the COVID-19 pandemic. The results showed an increase in the knowledge of the training participants before and after the counselling. This service activity can be useful in increasing knowledge and understanding of how to process Moringa leaves into a tea that infants and toddlers can consume. This has an important role in overcoming and preventing the problem of malnutrition in infants and toddlers to improve the community's standard of living.
Sosialisasi Penyakit pada Sapi dan Kambing Serta Pencegahannya di Desa Salarri Kecamatan Limboro, Polewali Mandar
Authors: Sukoco Hendro , Ali Najmah , Susanti Irma , Irfan Muhammad , Agustina Agustina , Suhartina Suhartina , Marsudi Marsudi , Susanti Eni
Published: July 2022

Penyakit masih menjadi kendala utama peternak di Indonesia, terutama peternakan rakyat, hal ini dikarenakan kondisi iklim tropis dan sumber daya peternak yang tergolong rendah pengetahuannya tentang penyakit, sehingga kurang memperhatikan dalam memelihara ternaknya, terutama yang berkaitan pencegahan dan pengendalian penyakit. Desa Salarri merupakan salah satu desa yang terdapat di Kecamatan Limboro, Polewali Mandar. Sebagian besar masyarakat di desa tersebut berprofesi sebagai peternak sapi dan kambing. Berdasarkan hasil identifikasi permasalahan bersama dengan Kepala Desa setempat diperoleh bahwa minimnya pengetahuan para peternak di Desa Salarri terkait dengan penyakit pada sapi dan kambing serta upaya pencegahannya. Sehingga perlu dilakukan sosialisasi mengenai penyakit pada sapi dan kambing serta pencegahannya di Desa Salarri Kecamatan Limboro, Polewali Mandar. Kegiatan ini dilaksanakan pada hari Kamis, 24 Maret 2022 di Aula Kantor Desa Salarri. Adapun metode yang digunakan pada kegiatan ini adalah ceramah dan tanya jawab. Sasaran dari kegiatan ini adalah peternak yang ada di Desa Salarri. Hasil yang diperoleh dari kegiatan ini adalah terlaksananya kegiatan sosialisasi dengan baik dan lancar. Dengan adanya kegiatan ini para peternak di desa tersebut mendapatkan pengetahuan baru mengenai penyakit pada sapi dan kambing serta upaya pencegahannya.The disease is still the main obstacle for breeders in Indonesia, especially on smallholder farms, this is due to tropical climate conditions and breeders' resources which are relatively low in knowledge about diseases, so they pay less attention to raising livestock, especially those related to disease prevention and control. Salarri Village is one of the villages located in Limboro District, Polewali Mandar. Most of the people in the village work as cattle and goat breeders. Based on the results of the identification of problems with the local Village Head, it was found that the farmers in Salarri Village lacked knowledge regarding diseases in cattle and goats and their prevention efforts. So it is necessary to disseminate information about diseases in cattle and goats and their prevention in Salarri Village, Limboro District, Polewali Mandar. This activity was held on Thursday, March 24, 2022, in the Salarri Village Office Hall. The method used in this activity is lecture and question and answer. The target of this activity is farmers in Salarri Village. The results obtained from this activity are the implementation of socialization activities well and smoothly. With this activity, farmers in the village gain new knowledge about diseases in cattle and goats and their prevention efforts.
Pelatihan Pembuatan Hand Sanitizer Menuju Desa Cerdas Kesehatan Di Desa Cangkir, Kecamatan Driyorejo, Kabupaten Gresik
Authors: A'yuni Qurrota , Widati Alfa Akustia , Setyawati Harsasi , Widiyanti Atik , Purkan Purkan , Khasanah Miratul , Ardiarto Tokok , Prasetyo A. Budi , Purwaningsih Aning , Wafiroh Siti , Sumarsih Sri , Ramadhan Rico , Hadi Sofijan , Makanty Kariza , Habibi Ahlan Riwahyu , Salsabella Aulianitha
Published: July 2022

Hand sanitizer merupakan cairan atau gel pembersih tangan yang memiliki sifat sebagai antibakteri dalam menghambat hingga membunuh bakteri. Dengan demikian hand sanitizer lebih efektif dalam membasmi kuman. Berdasarkan penelitian The Centers for Disease Control and Prevention (CDC), hand sanitizer dengan kandungan alkohol minimal 60% dapat berfungsi sebagai antibakteri maupun antivirus. Hand sanitizer pernah menjadi barang langka di puncak pandemi pada tahun 2020, karena pembelian yang masif dari masyarakat Indonesia. Langkanya hand sanitizer di beberapa toko dan apotek membuat harganya menjadi mahal. Kegiatan Pengabdian Kepada Masyarakat ini bertujuan untuk meningkatkan pengetahuan akan pentingnya kesehatan dan kemungkinan penyebaran kuman terutama virus dan bakteri serta upaya untuk mengantisipasinya. Tujuan yang lain yaitu untuk meningkatkan keterampilan masyarakat dalam pembuatan hand sanitizer. Rangkaian kegiatan ini diselenggarakan di Desa Cangkir, Kecamatan Driyorejo, Kabupaten Gresik pada Bulan November-Desember 2021 secara luring dengan menerapkan protokol kesehatan dengan peserta Ibu-Ibu PKK dan Kader PKK. Kegiatan ini dilakukan melalui metode pendampingan dan demonstrasi dengan presentasi materi dan praktik langsung. Kegiatan ini memberikan dampak yang positif bagi masyarakat Desa Cangkir dalam menghadapi Pandemi Covid-19 saat ini. Hand sanitizer is a liquid or gel that has antibacterial properties to inhibit and kill bacteria. Thus, hand sanitizer is more effective in eradicating germs. Based on research from The Centers for Disease Control and Prevention (CDC), alcohol-based hand sanitizers that contain at least 60% alcohol can function as both antibacterial and antivirus. Hand sanitizer was once a scarce item at the height of the pandemic in 2020, due to massive purchases from the Indonesian people. The scarcity of hand sanitizers in some shops and pharmacies makes the price expensive. This Community Service activity aims to increase knowledge of the importance of health and the possibility of spreading germs, especially viruses and bacteria, and efforts to anticipate them. Another aim is to improve community skills in making hand sanitizers. This series of activities were held in Cangkir Village, Driyorejo District, Gresik Regency in November-December 2021 via offline by implementing health protocols with PKK women and PKK Cadres as participants. This activity is carried out through mentoring and demonstration methods with presentations and hands-on practice. This activity has a positive impact on the Cangkir Village community in dealing with the current Covid-19 Pandemic.
OBTAINING AN IN-DEPTH UNDERSTANDING OF THE ASSURANCE DIMENSION OF SERVQUAL IN THE SPA INDUSTRY: A CASE OF SPAS IN BANGKOK
Authors: Sangpikul Aswin
Published: August 2022

Purpose - Among the five SERVQUAL dimensions, reliability is one of the most criticised dimensions because it is ambiguous and interpreted differently in the service literature. In addition, perceived hygiene, which is related to the attribute of safety, is becoming increasingly important in customer perceptions COVID -19 in the hospitality and tourism industries. In this study, three different sources of information are examined using a qualitative, exploratory methodology to gain a better understanding of the dimension of safety in the spa industry, focusing on spas in Bangkok. Design/methodology - Three different sources of information (secondary data, expert interviews, and customer interviews) are examined and interpreted through a content analysis methodology. Findings - There are two main findings. First, the assurance dimension of spa service quality can be sub-divided into four key categories: 1) product assurance 2) staff assurance 3) physical assurance and 4) process assurance. Second, perceived hygiene during the COVID-19 pandemic is integrated into the assurance attributes of spa service quality. Originality - The study advances knowledge on the assurance dimension in relation to spa service quality. In addition, the assurance dimension of SERVQUAL in the spa industry has been conceptualised in regard to the current situation.
KERAGAMAN GENETIK Taxus SumatranaDARI POPULASI ALAM DI JAMBI MENGGUNAKAN PENANDA RAPD
Authors:   Balai Besar Litbang Bioteknologi dan Pemuliaan Tanaman Hutan, Prihatini Istiana , Frianto Dodi ,   Balai Penelitian Teknologi Serat Tanaman Hutan, Novriyanti Eka , Nurtjahjaningsih ILG , Widyatmoko AYPBC
Published: August 2022

The natural population of Taxus sumatrana in several areas in southern Asia, including Indonesia, has decreased in number. In Sumatra, populations of less than 20 trees/ha were found in the Gunung Kerinci and Gunung Tujuh areas, in Kerinci District, Jambi. Conservation efforts to protect this species from extinction are being carried out, for example, exploring seeds from natural populations for ex-situ plantations. The genetic diversity information of Taxus is required to develop conservation strategies for this species. This research aimed to observethe genetic diversity of Taxus from Gunung Tujuh and Gunung Kerinci populations in Jambi. The level of genetic diversity of 44 individuals from those populations was analyzed using ten markers of RAPD. The application of thosemarkers produced 104 loci used in data analysis using the GenAlex version 6.5 software. The result showed the heterozygosity value described the moderate level of genetic diversity of the two observed populations of 0,33±0.14 (Gunung Tujuh) and 0,35±0.14 (Gunung Kerinci). The genetic distance between the two populations (0,097) and genetic similarity (0,908) indicate that the two populations have a moderate variation in genetic structure. This study shows that the two populations have variations in geneticstructure at medium level although geographically close. Genetic conservation efforts for Taxus species in the future should involve more individuals from both populations and separate them as two different populations
Implementasi Augmented Reality untuk Pengembangan Aplikasi Pengenalan Senjata Tradisional Kujang
Authors: Khairi Muhammad Azhar , Munandar TB Ai , Setiawati Siti
Published: August 2022

Kujang merupakan salah satu senjata tradisional yang menjadi ciri khas Jawa Barat. Namun masih banyak masyarakat yang belum mengetahui makna dan jenis-jenis dari kujang. Untuk mengenal kujang saat ini sangat sulit, dikarenakan sedikitnya masyarakat yang mempunyai atau mengkoleksi kujang. Dan juga tidak semua museum mempunyai jenis-jenis kujang yang lengkap, seperti Museum Pusaka Taman Mini Indonesia Indah (TMII). Museum tersebut hanya memiliki 4 jenis kujang yang dapat diperkenalkan. Informasi yang diberikan kepada pengujung juga tidak terlalu banyak. Penelitian ini bertujuan untuk mengembangkan aplikasi pengenalan senjata tradisional kujang menggunakan augmented reality, sehingga memudahkan pengunjung Museum Pusaka Taman Mini Indonesia Indah (TMII) untuk mengenal kujang dengan melihat bentuk secara 3D serta menambahkan materi mengenai kujang. Penggunaan aplikasi augmented reality ini menggunakan marker yang nantinya akan dideteksi oleh kamera dan memunculkan objek 3D. Pembuatan aplikasi augmented reality ini menggunakan tools vuforia. Hasil penelitian memperlihatkan bahwa aplikasi yang dikembangkan sangat diterima dengan baik oleh pengguna. Hal ini diperlihatkan dengan nilai system usability scale dari 58 responden yang menghasilkan skor rata-rata SUS sebesar 82,97. Skor tersebut termasuk ke dalam grade scale B, adjective rating good, dan acceptable ranges high.

Kata kunci: kujang, augmented reality, marker, vuforia.
Harvesting Context and Mining Emotions Related to Olfactory Cultural Heritage
Authors: Massri M.Besher , Novalija Inna , Mladenić Dunja , Brank Janez , Graça da Silva Sara , Marrouch Natasza , Murteira Carla , Hürriyetoğlu Ali , Šircelj Beno
Published: August 2022

This paper presents an Artificial Intelligence approach to mining context and emotions related to olfactory cultural heritage narratives, in particular to fairy tales. We provide an overview of the role of smell and emotions in literature, as well as highlight the importance of olfactory experience and emotions from psychology and linguistic perspectives. We introduce a methodology for extracting smells and emotions from text, as well as demonstrate the context-based visualizations related to smells and emotions implemented in a novel Smell Tracker tool. The evaluation is performed using a collection of fairy tales from Grimm and Andersen. We find out that fairy tales often connect smell with emotional charge of situations. The experimental results show that we can detect smells and emotions with F1 score of 92.7 and 79.2, respectively.
Performance Comparison of a Duplex Implementation of the CDC EUA 2019-nCoV Assay with the Seegene Allplex-SARS-CoV-2 Assay for the Detection of SARS-CoV-2 in Nasopharyngeal Swab Samples
Authors: Jiménez Karen Marcela , Fonseca-Mendoza Dora Janeth , Morel Adrien , Ortega-Recalde Oscar , Contreras Nora , Velandia-Piedrahita Camilo Andres , Steevens Adriana , Caldas Luisa , Ribón Juan Pablo , Sanchez Martha , Restrepo Carlos Martín , Cabrera Rodrigo
Published: August 2022

RT-PCR tests have become the gold standard for detecting the SARS-CoV-2 virus in the context of the COVID-19 pandemic. Because of the extreme number of cases in periodic waves of infection, there is a severe financial and logistical strain on diagnostic laboratories. For this reason, alternative implementations, and validations of academic protocols, that employ the lowest cost and most widely available equipment and reagents found in different regions, is essential. In this study, we report an alternative implementation of the EUA 2019-nCoV CDC assay which uses a previously characterized duplex PCR reaction for the N1 and RNAse P target regions and an additional uniplex reaction for the N2 target region. Taking advantage of the Abbott m2000 Sample Preparation System and NEB Luna Universal Probe One-Step RT-qPCR kit, some of the most widely available and lowest cost nucleic acid extraction and amplification platforms, this modified test shows a state-of-the-art analytical and clinical sensitivities and specificities, when compared with the Seegene Allplex-SARS-CoV-2 assay. This implementation has the potential to be verified and implemented by diagnostic laboratories around the world to guarantee low-cost RT-PCR tests that can take advantage of widely available equipment and reagents.
On the Surface Modification of LLZTO with LiF via a Gas-Phase Approach and the Characterization of the Interfaces of LiF with LLZTO as well as PEO+LiTFSI
Authors: Donzelli Manuel , Ferber Thimo , Vanita Vanita , Waidha Aamir Iqbal , Müller Philipp , Mellin Maximilian , Hausbrand René , Jaegermann Wolfram , Clemens Oliver
Published: August 2022

In this study we present gas-phase fluorination as a method to create a thin LiF layer on Li6.5La3Zr1.5Ta0.5O12 (LLZTO). We compare these fluorinated films with LiF films produced by RF-magnetron sputtering, where we investigated the interface between the LLZTO and the deposited LiF showing no formation of a reaction layer. Furthermore, we investigate the ability of this LiF layer as a protection layer against Li2CO3 formation in ambient air. By this we show that Li2CO3 formation is absent at the LLZTO surface after 24 h in ambient air supporting the protective character of the formed LiF films and hence could enhance the handling of LLZTO in air for battery production. With respect to the use within hybrid electrolytes consisting of LLZTO and a mixture of polyethylene oxide (PEO) and Lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) we also investigated the interface between the formed LiF films and a mixture of PEO LiTFSI by X-ray photoelectron spectroscopy (XPS) showing decomposition of the LiTFSI at the interface.
Slope Safety Risk Analysis of The Embankments Made of Different Landfill-Mined Waste
Authors: Verma Abhay Kumar , Dhriyan Shivani Singh , Prasad Arun
Published: August 2022

Municipal solid waste management is a growing worldwide challenge. Landfill mining is a promising technique to reduce MSW landfills. In the present study, arbitrary embankments made of different MSW fractions are analyzed to find the safety factor of their slopes. Properties of Municipal solid waste fines (MSWF), Shredded MSW, MSW Incineration Ash, and MSW having particles less than 35 mm are used in the analysis. For doing the same, finite element-based application 'Plaxis-2D' is used. The safety of slopes is assessed while the water table is inserted, and a uniform load is applied to the embankment to establish how well they will perform in critical situations. It was found that the slope made of shredded MSW is most safe due to its low density and high friction angle, while the least safe slope is made of MSW having less than 35 mm fractions.
Automatic Segmentation and Quantitative Assessment of Stroke Lesions on MR images
Authors: Verma Khushboo , Kumar Satwant , Paydarfar David
Published: August 2022

Lesion studies are crucial in establishing brain-behavior relationships, and accurately segmenting the lesion represents the first step in achieving this. Manual lesion segmentation is the gold standard for chronic strokes. However, it is labor-intensive, subject to bias, and limits sample size. Therefore, our objective is to develop an automatic segmentation algorithm for chronic stroke lesions on T1-weighted MR images. Methods: To train our model, we utilized an open-source dataset: ATLAS v2.0 (Anatomical Tracings of Lesions After Stroke). We partitioned the dataset of 655 T1 images with manual segmentation labels into five subsets and performed a 5-fold cross-validation to avoid overfitting of the model. We used a deep neural network (DNN) architecture for model training. Results: To evaluate the model performance, we used three metrics that pertain to diverse aspects of volumetric segmentation including shape, location, and size. The Dice similarity coefficient (DSC) compares the spatial overlap between manual and machine segmentation. The average DSC was 0.65 (0.61- 0.67; 95% bootstrapped CI). Average symmetric surface distance (ASSD) measures contour distances between the two segmentations. ASSD between manual and automatic segmentation was 12mm. Finally, we compared the total lesion volumes and the Pearson correlation coefficient (ρ) between the manual and automatically segmented lesion volumes, which was 0.97(p-value < 0.001). Conclusions: We present the first automated segmentation model trained on a large multicentric dataset. This model will enable automated on-demand processing of MRI scans and quantitative chronic stroke lesion assessment.
Communication Systems Performance at mm and THz as a Function of Rain Rate Probability Density Function Model
Authors: Kupferman Judy , Arnon Shlomi
Published: August 2022

6G is already being planned and will employ much higher frequencies, leading to a revolutionary era in communication between people as well as things. It is well known that weather, especially rain, can cause increased attenuation of signal transmission for higher frequencies. The standard methods for evaluating the effect of rain on symbol error rate are based on long-term averaging. These methods are an inaccurate, which results with an inefficient system design. This is critical regarding bandwidth scarcity and energy consumption and requires a more significant margin of effort to cope with the imprecision. Recently we have developed a new and more precise method for calculating communication system performance in case of rain, using the probability density function of rain rate. For high rain rate (above 10mm/hr), for a typical set of parameters, our method shows the symbol error rate in this range to be higher by orders of magnitude than that found by ITU standard methods. Our model also indicates that sensing and measuring the rain rate probability is important in order to provide the required bit error rate to the users. To the best knowledge of the authors, this novel analysis is unique. It can constitute a more effi-cient performance metric for the new era of 6G communication and prevent disruption due to incorrect system design. Keywords: atmospheric propagation, communication system performance, attenuation, com-munication
High Performance Parallel Pseudorandom Number Generator on Cellular Automata
Authors: Levina Alla , Mukhamedjanov Daniyar , Bogaevskiy Danil , Lyakhov Pavel , Valueva Maria , Kaplun Dmitrii
Published: August 2022

Nowadays the practice of developing algorithms to maintain the confidentiality of data shows that there is a lack of some features, such as velocity, predictability, etc. Generating pseudorandom numbers is one such problem that lies in the basement of many algorithms, even in hardware microprograms. An unreliable generator can cause cyberattacks on it, despite the security in the upper layers. At the same time, the algorithm should be fast enough to provide uninterrupted circuit work for the entire system. The paper presents a new algorithm generating pseudorandom numbers on cellular automata, which is not only fast and easy-repeating, but unpredictable enough and can be used in cryptographic systems. Using the NIST statistical test suite for random and pseudorandom number generators (PRNG), it is shown that the presented algorithm is more than three times superior to the state-of-the-art methods and algorithms in terms of ? − ?????. A high level of the presented algorithm’s parallelization allows for implementation it effectively on calculators with parallel structure. CPU-based architecture, FPGA-based architecture, CUDA- based architecture of PRNG and different PRNG implementations are presented to confirm high performance of the proposed solution.
The Relationship between Consuming Fashion and Self-Confidence on the Buying Behaviour in the Clothing Market as a Mediator
Authors: Zam Milad , Tavakoli Mohammadhosein , Ramezanian Hasan , Rezasoltani Amin
Published: August 2022

As a mediator variable, self-confidence is one of the most effective elements of the decision-making process of consumer behaviour. This research has studied the effects of different aspects of consuming fashion on the self-confidence and behaviour of consumers in Tehran’s clothing market. This study has considered the acceptance of new products, interest in mode and fashion, utilitarianism, and personal taste in its analysis. This research aims to understand the fashion buying behaviour amongst Iranian consumers in consideration of their attitude towards self-confidence and aspects of fashion consumption. The statistic sample is 400 consumers from Tehran’s clothing market who have been chosen based on the random availability procedure. The primary tool in this research was a questionary used to testify the assumptions and a model fit created by using structural equations and factor analysis. This research showed that the interest in mode and fashion, personal taste, utilitarianism, and new products positively impact self-confidence. In addition, the positive impact of self-confidence on fashion buying behaviour was confirmed.
Mode Choice of City Tourists: Discrete Choice Modeling Based on Survey Data from A Major German City
Authors: Harz Jonas , Sommer Carsten
Published: August 2022

With growing city tourism, there is an increasing need for urban travel demand models to consider traffic generated by visitors. Existing research has concentrated on socio-demographic and journey-related factors to determine what influences the mode choice of tourists. In contrast, revealed preference data, like travel time, is almost never considered. In this article, we present the results of discrete choice modeling of city tourists’ mode choice based on revealed preference data from a survey we conducted in Kassel, Germany. We used multinomial logit models and determined the model parameters using maximum likelihood estimations. Surprisingly, travel time played a smaller role in mode choice than understood from previously established knowledge about everyday mobility. In the final model, travel time was only significant for the alternative walking. Also, most other sociodemographic and journey-related variables showed no significant influence. The final model reproduced the mode choice, but the goodness of fit was lower than expected from other research. We conclude that modeling the travel behavior of tourists is more complex than everyday mobility. An alternative approach that we suggest would be to model trip chains rather than single trips.
Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics
Authors: Chandel Arvind Kumar Singh , Bhalani Dixit , Bhingaradiya Nutan , Kumar Avinash
Published: August 2022

The low water solubility of any pharmacoactive molecules limits their pharmacological potential but the solubility parameter cannot compromise, so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with low solubility convey a higher risk of failure for drug innovation and development. Pharmacokinetics, pharmacodynamics, and several other parameters, such as drug distribution, protein binding and absorption, are majorly affected by their solubility. Among all pharmaceutical dosage forms, the oral dosage forms cover more than 50 %, and the drug molecule should be water-soluble. For good therapeutic activity by the drug molecule on the target site, solubility and bioavailability are crucial factors. The pharmaceutical industry screening programs identified that around 40% of new chemical entities (N.C.E.s) face various difficulties at the formulation and development step. These pharmaceuticals are attributed to their less solubility and bioavailability. The bioavailability and drug solubility enhancement are significant challenges in the area of pharmaceutical formulations. According to the Classification of Biopharmaceutics, Class II and IV drugs (APIs) exhibits poor solubility, lower bioavailability, and less dissolution. Various technologies are discussed in this article to improve the solubility of the poorly water-soluble drug, for example, complexation of active molecules, utilization of emulsion formation, micelles, microemulsions, cosolvents, polymeric micelles preparation, particle size reduction technologies, pharmaceutical salts, prodrugs, solid-state alternation technique, soft gel technology, drug nanocrystals, solid dispersion methods, crystal engineering techniques and nanomorph technology. This review mainly describes several other advanced methodologies for solubility and bioavailability enhancement, such as crystal engineering, micronization, solid dispersions, nano sizing, use of cyclodextrins, solid lipid nanoparticles, colloidal drug delivery systems and drug conjugates, by some appropriate research reports.
Can Biomarkers of Oxidative Stress in Serum Predict Disease Severity in West Nile Virus Infection? A Pilot Study
Authors: Van Herreweghe Maxim , Breynaert Annelies , De Bruyne Tess , Popescu Corneliu Petru , Florescu Simin-Aysel , Lustig Yaniv , Schwartz Eli , Gobbi Federico Giovanni , Hermans Nina , Huits Ralph
Published: August 2022

Oxidative stress appears to be associated with more severe disease in WNV infected patients. Our preliminary findings warrant prospective studies to investigate the correlation of oxidative stress with clinical outcomes and severity of WNV infection.
Connect to Protect: Dynamics and Genetic Connections of Highly Pathogenic Avian Influenza Outbreaks in Poultry from 2016 to 2021 in Germany
Authors: King Jacqueline , Staubach Christoph , Lüder Christiane , Koethe Susanne , Günther Anne , Stacker Lina , Rubbenstroth Dennis , Dietze Klaas , Grund Christian , Conraths Franz J. , Harder Timm , Beer Martin , Pohlmann Anne
Published: August 2022

During autumn/winter in 2016 – 2017 and 2020 – 2021, highly pathogenic avian influenza viruses (HPAIV) caused severe outbreaks in Germany and Europe. Multiple clade 2.3.4.4b H5 HPAI subtypes were responsible for increased mortality in wild birds and high mortality and massive losses in the poultry sector. To clarify putative entry sources and delineate interconnections between outbreaks in poultry holdings and wild birds, we applied whole-genome sequencing and phylodynamic analyses combined with the results of epidemiological outbreak investigations. Varying outbreak dynamics of the distinct reassortants allowed for the identification of individual, putatively wild bird-mediated entries into backyard holdings, several clusters comprising poultry holdings, local virus circulation for several weeks, direct farm-to-farm transmission and potential reassortment within a turkey holding with subsequent spill-over of the novel reassorted virus into the wild bird population. Whole-genome sequencing allowed for allowed for a unique high-resolution molecular epidemiology analysis of HPAIV H5Nx outbreaks, recommended to be used as a standard tool. The presented detailed account of the genetic, temporal and geographical characteristics of the recent German HPAI H5Nx situation emphasizes the role of poultry holdings as an important source of novel genetic variants and reassortants.
Depolarizing Effects in Hydrogen Bond Energy in 310-Helices Revealed by Quantum Chemical Analysis
Authors: Kondo Hiroko X. , Nakamura Haruki , Takano Yu
Published: August 2022

Hydrogen-bond (H-bond) energies in 310-helices of short alanine peptides were systematically examined by precise DFT calculations with the negative fragmentation approach (NFA), a modified method based on the molecular tailoring approach. The contribution of each H-bond was evaluated in detail from the 310-helical conformation of total energies (whole helical model; WH3-10 model), and the results were compared with the property of H-bond in a-helix from our previous study. The H-bond energies of the WH3-10 model exhibited tendencies different from those exhibited by the -helix, in that they depended on the helical position of the relevant H-bond pair. H-bond pairs adjacent to the terminal H-bond pairs were observed to be strongly destabilized. The analysis of electronic structures indicated that structural characteristics cause the destabilization of the H-bond in 310-helices. We also found that the longer the helix length, the more stable the H-bond in the terminal pairs of the WH3-10 model, suggesting the action of H-bond cooperativity.
Experiences Shared by the (Future) Public Health Workforce during the COVD-19 Pandemic in Germany: Results of A Survey on Workload, Work Content, and Related Challenges among Students and Young Professionals
Authors: Fischer Florian , Wicherski Julia , Tobollik Myriam , McCall Timothy
Published: August 2022

Although previous studies have focused on the adverse effects of the COVID-19 pandemic on various professional groups (particularly in the health and nursing care sector), this study aims to close a research gap by assessing perspectives of students and young professionals in epidemiology and public health in Germany in terms of shifts in workload, work content, and related challenges caused by the pandemic. We conducted a cross-sectional survey between mid-February and mid-March 2022. Quantitative data were analyzed via standardized mean differences. Qualitative data based on answers to open-ended questions were analyzed via a qualitative content analysis. Overall, 172 individuals participated in this survey. Results indicate that students felt burdened the most by lack of exchange with other students and lecturers. Study participants employed in public health experienced changes in their employment, because they had changes in their work content- and administration-wise, which was accompanied with a high burden due to the workload. Multiple demands that can have an impact on both acquired skills and mental health during the professional qualification phase were mentioned by the participants. Therefore, more in-depth analyses are needed for investigating the impact the pandemic will have on the (future) public health workforce in the long run.
Novel Fabrication Tools for Dynamic Compression Targets with Engineered Voids Using Photolithography Methods
Authors: Pandolfi Silvia , Carver Thomas , Hodge Daniel , Leong Andrew FT , Kurzer-Ogul Kelin , Hart Philip , Galtier Eric , Khaghani Dimitri , Cunningham Eric , Nagler Bob , Lee Hae Ja , Bolme Cindy , Ramos Kyle , Li Kenan , Liu Yanwei , Sakdinawat Anne , Marchesini Stefano , Kozlowski Pawel Marek , Curry Chandra Breanne , Decker Franz-Josef , Vetter Sharon , Shang Jessica , Aluie Hussein , Dayton Matthew , Montgomery David S , Sandberg Richard L , Gleason Arianna E
Published: August 2022

Mesoscale imperfections, such as pores and voids, can strongly modify the properties and the mechanical response of materials under extreme conditions. Tracking the material response and microstructure evolution during void collapse is crucial for understanding its performance. In particular, imperfections in ablator materials, such as voids, can limit the efficiency of the fusion reaction and ultimately hinder ignition. To characterize how voids influence the response of materials during dynamic loading and seed hydrodynamic instabilities, we have developed a tailored fabrication procedure for designer targets with voids at specific locations. Our procedure uses SU-8 as a proxy for ablators materials and hollow silica microspheres as proxy for voids and pores. By using photolithography to design the targets’ geometry, we demonstrate precise and highly reproducible placement of a single void within the sample, which is key for a detailed understanding of its behavior under shock compression. This fabrication technique will benefit high-repetition rate experiments at x-ray and laser facilities. Insight from shock compression experiments will provide benchmarks for the next generation of microphysics modelling.
Regulatory T Cell Depletion Using A CRISPR Fc-Optimized CD25 Antibody
Authors: Van Elsas Marit J. , Van der Schoot Johan M.S. , Bartels Alexander , Steuten Kas , Van Dalen Duco , Wijfjes Zacharias , Figdor Carl G. , Van Hall Thorbald , Van der Burg Sjoerd H. , Verdoes Martijn , Scheeren Ferenc A.
Published: August 2022

Regulatory T cells (Tregs) are major drivers behind immunosuppressive mechanisms and present a major hurdle for cancer therapy. Tregs are characterized by high expression of CD25, which is a potentially valuable target for Treg depletion to alleviate immune suppression. The preclinical anti-CD25 (αCD25) antibody, clone PC-61, has met with modest anti-tumor activity, due to its capacity to clear Tregs from circulation and lymph nodes but not those that reside in the tumor. Optimization of the Fc domain of this antibody clone has been shown to enhance intratumoral Treg depletion capacity. Here, we generated a stable cell line that produces optimized recombinant Treg depleting antibodies. A genome engineering strategy in which CRISPR-Cas9 was combined with homology directed repair (CRISPR-HDR) was utilized to optimize the Fc domain of the hybridoma PC-61 for effector functions by switching it from the original rat IgG1 to a mouse IgG2a isotype. In a syngeneic tumor mouse model the resulting αCD25-m2a antibody mediated effective depletion of tumor resident Tregs leading to a high effector T cell (Teff) to Treg ratio. Moreover, combination of the αCD25-m2a with αPD-L1 treatment augmented tumor eradication in mice, demonstrating the potential for αCD25 as a cancer immunotherapy.
Taking a Promising Vaccine Candidate Further: Efficacy of ASFV-G-ΔMGF after Intramuscular Vaccination of Domestic Pigs and Oral Vaccination of Wild Boar
Authors: Deutschmann Paul , Carrau Tessa , Sehl-Ewert Julia , Forth Jan Hendrik , Viaplana Elisenda , Mancera Jose Carlos , Urniza Alicia , Beer Martin , Blome Sandra
Published: August 2022

African swine fever (ASF) is a pandemic threat to the global pig industry and wild suids. A safe and efficacious vaccine could monumentally assist in disease eradication. In the past years, promising live attenuated vaccine candidates emerged in proof-of-concept experiments, among them, “ASFV-G-∆MGF”. In our study, we tested the vaccine candidate in three animal experiments intramuscularly in domestic pigs one orally in wild boar. Further, a macrophage-grown vaccine virus and a virus grown on permanent cells could be employed. Irrespective of the production system of vaccine virus, a two-dose intramuscular immunization could induce close to sterile immunity with full clinical protection against challenge infection. After oral immunization, 50% of the vaccinees seroconverted and all responders were completely protected against subsequent challenge. All non-responders developed ASF upon challenge with two acute lethal infections and two mild and transient courses. The latter results show a lower efficiency after oral administration that would have to be taken into consideration when designing vaccination-based control measures. Our findings suggest that “ASFV-G-∆MGF” could help to contain the disease under an appropriate vaccination campaign. Further research is needed to characterize safety aspects and define possible improvements of oral efficiency.
The development of independence of people living with dementia while performing an artistic painting activity
Authors: González Cabañes Eduardo , Kuhn Penelope L. , Ortega-Merino Sara , Ullán de la Fuente Ana M. , Herringer Lawrence , Price Shane , Saldaña Carla , Madden Lucy , Bartel Anna , Rojo-Hernández Estela
Published: August 2022

This study explored the practice and spacing-of-practice effects in people living with dementia during an artistic painting activity. The video recordings of 23 participants were systematically observed during their first and fourth session of the activity. Improvements in independence, engagement, and well/ill-being expressions were analyzed from the first to the fourth session. Moreover, it was analyzed whether a group who had practiced three times a week (n = 12) improved more than a group who had practiced once a week (n = 13). Participants became more independent as they practiced, but the spacing of the sessions did not show any significant effect. Participants with severe dementia showed greater independence improvements than participants with mild to moderate dementia, although they required significantly more assistance throughout the entire study. The positive rates in active engagement and well/ill-being expressions suggest that artistic painting activities promote the motivation and well-being of participants, including those in the severe stage of dementia.
An Occurrence Description Logic
Authors: Badie Farshad , Gotzsche Hans
Published: July 2022

Description Logics (DLs) are a family of well-known terminological knowledge representation formalisms in modern semantics-based systems. This research focuses on analysing how our developed Occurrence Logic (OccL) can conceptually and logically support the development of a description logic. OccL is integrated into the alternative theory of natural language syntax in Deviational Syntactic Structures under the label ‘EFA(X)3’ (or the third version of Epi-Formal Analysis in Syntax, EFA(X), which is a radical linguistic theory). From the logical point of view, OccL is a formal logic that mainly deals with the occurrences of symbols as well as with their priorities within linguistic descriptions, i.e. natural language syntax, semantics and phonology. In this article—based on our OccL-based definitions of the concepts of strong implication and occurrence value as well as of the logical concept Identical Occurrence Constructor (IDOC) that is the most fundamental logical concept in our formalism—we will model Occurrence Description Logic (ODL). Accordingly, we will formally-logically analyse ‘occurrence(s) of symbol(s)’ within descriptions of the world in ODL. In addition, we will analyse and assess the logical concepts of occurrence and occurrence priority in ODL. This research can make a strong logical background for our future research in the development of a Modal Occurrence Description Logic.
PENINGKATAN KEMAMPUAN MEMBACA KITAB KUNING MELALUI MANAJEMEN PESERTA DIDIK DI PONDOK PESANTREN NURUL QUR’AN PAKUNDEN
Authors: Mahfud  , Rohmanu Abid
Published: August 2022

Salah satu problematika pondok pesantren adalah output. Rendahnya kemampuan santri dalam membaca kitab kuning merupakan permasalahan yang perlu dicari solusinya. Tulisan ini akan mengungkap bagaimana manajemen peserta didik diterapkan, faktor-faktor yang mempengaruhi, serta dampak dari manajemen peserta didik terhadap kemampuan membaca kitab kuning. Tulisan ini menggunakan metode kualitatif dengan pendekatan studi kasus. Implementasi manajemen peserta di Pondok Pesantren Nurul Qur’an dengan berbagai faktor pendukung dan penghambatnya, berdampak pada peningkatan kemampuan santri dalam membaca kitab kuning. Keberhasilan peningkatan mutu peserta didik merupakan salah satu hasil dari baiknya Implementasi Manajemen peserta didik.