bluuebunny/crossref_metadata_2025 huggingface dataset:
Integration of railway infrastructure topological description elements from the microL2 to the macroN0,L0 level of detail
Authors: Hlubuček Adam
Published: March 2023

The paper presents the method of integration, which is supposed to be applied to the structure of the railway infrastructure topological description system expressed at the level of detail designated as microL2 in order to transform it into the structure expressed at the level of detail designated as macroN0,L0 . The microL2 level is the level of detail at which individual tracks in the structural sense and turnout branches are recognized, while the macroN0,L0 level is the level of individual operational points and line sections. The proposed integration algorithm takes into account both the parameter values of the individual elements appearing at the reference level of detail microL2 and their topological interconnectedness. Based on these aspects, these elements are integrated into the elements of the derived level of detail macroN0,L0 that can be described by the transformed parameter values. The relations between the respective elements are also transformed accordingly. While describing the transformation algorithm, the terminology and principles of the UIC RailTopoModel are used.
Hyperspectral imaging enables the differentiation of differentially inflated and perfused pulmonary tissue: a proof-of-concept study in pulmonary lobectomies for intersegmental plane mapping
Authors: Ellebrecht David B.
Published: March 2023

Objectives

The identification of the intersegmental plane is a major interoperative challenges during pulmonary segmentectomies. The objective of this pilot study is to test the feasibility of lung perfusion assessment by Hyperspectral Imaging for identification of the intersegmental plane.

Methods

A pilot study (clinicaltrials.org: NCT04784884) was conducted in patients with lung cancer. Measuring tissue oxygenation (StO2; upper tissue perfusion), organ hemoglobin index (OHI), near-infrared index (NIR; deeper tissue perfusion) and tissue water index (TWI), the Hyperspectral Imaging measurements were carried out in inflated (Pvent) and deflated pulmonary lobes (PnV) as well as in deflated pulmonary lobes with divided circulation (PnVC) before dissection of the lobar bronchus.

Results

A total of 341 measuring points were evaluated during pulmonary lobectomies. Pulmonary lobes showed a reduced StO2 (Pvent: 84.56% ± 3.92 vs. PnV: 63.62% ± 11.62 vs. PnVC: 39.20% ± 23.57; p<0.05) and NIR-perfusion (Pvent: 50.55 ± 5.62 vs. PnV: 47.55 ± 3.38 vs. PnVC: 27.60 ± 9.33; p<0.05). There were no differences of OHI and TWI between the three groups.

Conclusions

This pilot study demonstrates that HSI enables differentiation between different ventilated and perfused pulmonary tissue as a precondition for HSI segment mapping.
‚Hervorbringende Organe‘, ‚bildende Kraft‘?
Authors: Sophie Meincke Anne
Published: March 2023

This article presents Heidegger’s little-known theory of the organism developed in his 1929/30 lectureThe Fundamental Concepts of Metaphysicsand interprets it as an antithesis to Kant’s theory of the organism contained in hisCritique of Judgement(1790 and 1792/3). Heidegger drops Kant’s transcendental caveats in favour of a robust ontological understanding of organismic teleology. Moreover, Heidegger’s alternative approach draws attention to the fact that Kant’s notion of a ‘natural end’ (Naturzweck), by being tied to the idea of intelligent design, still places the organism too close to the machine, notwithstanding assumptions of a ‘formative force’ (bildende Kraft) and ‘productive organs’ (hervorbringende Organe). Heidegger, in contrast, analyses organismic purposiveness in terms of an instinctual capacity (triebhafte Fähigkeit) in which an organism’s organs are ontologically grounded as its products, and which explains the specificity of an organism’s wholeness, motility and relation to the world.
Das Phänomen der Verlegenheit und seine Rolle im personalen Lebenszusammenhang
Authors: von Kalckreuth Moritz
Published: March 2023

The aim of this paper is to provide a basic understanding of the phenomenon of embarrassment by connecting two general questions. Starting with two illustrative examples, it first examines how the phenomenon could be described and what different aspects can be identified. Apart from having an obvious affective or emotional aspect and being embodied in various forms of expression, embarrassment can be considered as having a social aspect because of its close connection to the social setting of a situation. Furthermore, it seems to have an atmospheric quality in that it is experienced not only by the embarrassed person but also by all those present. Secondly the role that embarrassment plays in the context of a person’s life is addressed. Though it is experienced as unpleasant, it can be understood as a form of adequately responding to certain social situations structured by ambiguity.
Zur Bedeutung von Verlegenheit für einen Begriff politischer Öffentlichkeit
Authors: Felgenhauer Katrin , Lehmann Robert
Published: March 2023

The paper examines the significance of embarrassment for a concept of political publicity. It is critical of how the common interpretation of this apparently social phenomenon as a “milder form of shame” leads to a functionalist interpretation. According to this interpretation, embarrassment regulates given normative structures by initiating or even motivating self-criticism. In contrast, the article shows, first, that embarrassment cannot occur at all in a public sphere that is thought of exclusively in normative terms, and second, that the phenomenon is primordially not reflexive. In embarrassment, one is not immediately “thrown back on oneself” but tries to find a relation to one’s public figure. A philosophical reflection on this pursuit reveals the constitution of normative structures. In this light, embarrassment presents itself as a genuinely political phenomenon.
Philosophie aktuell: Public Philosophy – brauchen wir das?
Authors: Marlen Esser Andrea
Published: March 2023

In recent years, calls for philosophy to interact more with the public have grown louder in the German-speaking world as well as elsewhere. Public philosophy, as it were, has a long-standing tradition, reaching back to Enlightenment-era German “Popularphilosophie” and of course to Socrates and the Sophists. This section presents four short articles on some current aspects of the public-philosophy debate: on the overall conditions for transferring content from academic philosophy to the public in Germany; on the relations between philosophers’ mediatic presence and their disciplinary expertise; on 18th-century guidelines for accessible philosophical writing; and on public philosophy as a social practice that is more than mere unidirectional knowledge transfer.
Putative anti-proliferative effect of Indian mustard (Brassica juncea) seed and its nano-formulation
Authors: Virk Promy , Awad Manal A. , Alanazi Meznah M. , Hendi Awatif A. , Elobeid Mai , Ortashi Khalid M. , Alrowaily Albandari W. , Bahlool Taghreed , Aouaini Fatma
Published: March 2023

Over the past few decades, nanotechnology has shown promising prospects in biomedicine and has a proven impact on enhancing therapeutics by facilitating drug delivery. The present study brings an amalgamation of nanoscience and “clean technology” by fabricating nature-friendly nanoparticles (NPs) sans the use of chemical surfactants using Indian mustard seed, Brassica juncea L. The as-synthesized NPs were characterized to assess their average size, crystallinity, morphology, and constituent functional groups through conventional techniques: dynamic light scattering (DLS), X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). The NPs were crystalline in nature and exhibited a mean size of 205.5 nm (PDI of 0.437) being primarily polygonal in shape. Additionally, the therapeutic efficacy of the green NPs was evaluated based on their cytotoxic effect against two human cancer lines, MCF-7 and HepG-2. Both the NPs and the bulk seeds showed a dose-dependent cytotoxic effect. However, an assessment of the antiproliferative/cytotoxic potential of the green NPs versus the bulk seeds showed that the NPs were relatively more efficacious on both cell lines. Taken together, the mustard seed NPs could be potential nutraceuticals considering the green credential in their mode of biosynthesis.
Study on the thermal stability and combustion performance of polyurethane foams modified with manganese phytate
Authors: Zhang Xu , Yuan Dehe , Sun Simiao , Li Handong , Wang Zhi , Xie Hua
Published: March 2023

A new environmental friendly flame retardant manganese phytate (MnPa) was prepared by a direct precipitation method and the polyurethane foam (PUF) modified with MnPa was obtained by a one-step all-water foaming method. The thermal stability and combustion performance of the MnPa-modified PUF (MnPUF) were investigated by using thermogravimetric (TG), thermal decomposition kinetics, smoke density characterization, limiting oxygen index (LOI) and UL-94 horizontal combustion test. The results indicated that the addition of MnPa significantly improved the thermal stability and combustion performance of the modified PUF. On the basis of the thermogravimetric analysis, Flynn-Wall-Ozawa method, Kissinger method and Coats Redfern method, it could be concluded that PUF with 7.5 wt% MnPa (MnPUF3) had the highest activation energy and the best thermal stability. Smoke density analysis, LOI and horizontal combustion analysis also showed that the addition of MnPa was positively correlated with smoke suppression, LOI value and burning time. The current research results can provide a reference for the subsequent flame retardant modification of PUF.
Microstructural characteristics and mechanical properties of rotary friction-welded dissimilar AISI 431 steel/AISI 1018 steel joints
Authors: Thirumalaikkannan Dhamothara kannan , Paramasivam Sivaraj , Visvalingam Balasubramanian , Sonar Tushar , Ivanov Mikhail , Murugaesan Seeman
Published: March 2023

The main objective of this study was to analyze the microstructural characteristics and strength performance of dissimilar AISI 431 steel/AISI 1018 steel joints developed using rotary friction welding. The microstructural characteristics of different regions of dissimilar rod-to-plate joints were analyzed using optical microscopy. The tensile properties and microhardness of dissimilar rod-to-plate joints were evaluated to assess the joint performance. The microhardness distribution across the cross-sectional region of dissimilar rod-to-plate joints was recorded and correlated with the tensile failure. Scanning electron microscopy was used to analyze the fractured region of dissimilar rod-to-plate tensile specimens. Results showed that the dissimilar AISI 431 steel/AISI 1018 steel joints steel exhibited a tensile strength of 650 MPa, a yield strength of 452 MPa, and a % elongation of 18%. The microhardness of the weld interface (WI) was higher up to 515 HV0.5. The grain growth and resulting lower hardness in heat-affected zone (HAZ) are mainly responsible for the failure of the joints in HAZ only. The superior tensile properties and greater interface hardness of dissimilar AISI 431 steel/AISI 1018 steel joints are correlated with the evolution of finer grain microstructure in the WI zone.
Wear performance analysis of B4C and graphene particles reinforced Al–Cu alloy based composites using Taguchi method
Authors: Sachit T. S. , Bongale Arunkumar , Kumar Satish , Jadhav Priya
Published: March 2023

In this study, the wear performance of boron carbide (B4C) and graphene (Gr) particles reinforced Al–Cu alloy composites was investigated. The composite samples were made using the solid-state manufacturing process. The wear performance was assessed using a pin-on-disc tribometer. The Taguchi optimization approach was used to determine the performance of each parameter. All experiments were carried out using the L27 array, which included three sets of parameters such as applied load, disc speed, and reinforcement percentage. The ANOVA approach was used to examine the impact of each parameter. According to the findings, the weight on the pin has the greatest influence on wear, followed by sliding speed and reinforcing percentage. The addition of B4C particles improves the wear resistance, and the Gr functions as a self-lubricating agent while in use. Scanning electron microscope analysis of worn-out samples revealed an abrasive type of wear process.
Word prosody of African versus European-origin words in Afro-European creoles
Authors: Agostinho Ana Lívia
Published: March 2023

This paper is concerned with word-prosodic systems of Afro-European creole languages that show a correlation between the lexical origin (African vs. European) and prosodic pattern. The discussion is based on the evidence from four languages: Saramaccan, Nigerian Pidgin English, Pichi, and Lung’Ie. I examine how the study of word-prosodic systems of creoles can contribute to phonological typology and to the debate of whether creoles are different from non-creoles. I hypothesize that such systems are the result of extreme language contact and can only be found in creole languages. The existence of these systems further confirms that sociohistorical processes – such as historic contact – can shape phonological systems. Finally, I conclude that the analysis of African-origin words is crucial to further our understanding of creole phonology.
The crystal structure of N′1,N′3-di((E)-benzylidene) isophthalohydrazide dihydrate, C
22
H
22
N
4
O
4
Authors: Lai Ni , Zhang Sheng-Ting , Zou Fei , Yuan Lin , Li Zhong-Yan
Published: March 2023

C
22

H
22

N
4

O
4

${\mathrm{C}}_{22}{\mathrm{H}}_{22}{\mathrm{N}}_{4}{\mathrm{O}}_{4}$

, monoclinic, C2/c (no. 15), a = 34.315(13) Å, b = 6.701(3) Å, c = 9.105(3) Å, β = 

98.510

(
4
)

°

$98.510(4){}^{\circ}$

, V = 2070.7(13) 

Å
3

${\mathrm{\mathring{\text{A}}}}^{3}$

, Z = 4,

R

g
t

${R}_{gt}$

(F) = 0.0461,

w

R

r
e
f

$w{R}_{ref}$

(

F
2

${F}^{2}$

) = 0.1413, T = 296(2) K.
Research on nonlinear tracking and evaluation of sports 3D vision action
Authors: Li Mingzhi , Wang Jucui , Jawarneh Malik , Bhatt Mohammed Wasim , Omarov Batyrkhan , Raffik Rasheed
Published: March 2023

In order to effectively upgrade the training quality of the athlete, the study of the three-dimensional optical steps of sports, a three-dimensional optical action amplitude tracing process based on improved reverse kinematics is discussed. The method passes through a pinhole camera, the model calibrate the camera imaging plane, the positioning mark appears in the marker point in the apart neighboring single-sequence action amplitude and then the five-point perspective imaging of the same line is captured on the same straight line by the camera on different positions and postures. The matching method’s accuracy and superiority are demonstrated through experimental evaluation and compared with other similar measures. This characteristic is distinguished by the left and right image frames of the same camera. The translational movement is altered in 10–80 mm/s and the rotational movement is adjusted in 10–300 mm/s. During the confirmation, the spinning of the operational target, the longitudinal movement and the spatial location of the rotation point Measurement, the calculation variability of the stereoscopic visual moving calculation system, is given, and the method of tracking the method is high, which lay the foundation for the promotion of the training quality of the athlete. The experimental findings from simulation demonstrate that the implemented approach has great searching accuracy, establishing a solid platform for further improving the quality of athletes’ training.
Appraisal and health risk assessment of potential toxic element in fruits and vegetables from three markets in Anambra state, Nigeria
Authors: Ekpunobi Uche E. , Onyekwere Fabian M. , Arinze Rosemary U. , Enenche Daniel N. , Omokpariola Daniel O. , Okechukwu Victor U.
Published: March 2023

The influence of anthropogenic activities has led to increase of potential toxic elements (PTEs) present in plant-based food sources, even in trace amounts; thus, it is known to pose a threat to human health over an extended period. The concentration levels of PTEs (Pb, Cu, Zn, Cd, Co and Ni) in soils and fruits and vegetables from three markets (Atani, Omor and Eke Awka) in Anambra state, Southeastern Nigeria were quantified and assessed using Atomic Absorption Spectrophotometer (AAS) instrument. The result of PTE (mg/kg) studied was in the order Zn > Cu > Pb > Ni > Co > Cd with the highest value for Zn (13.61 mg/kg) recorded in soil sample at Omor market. The mean concentrations of PTEs in soil of both evaluated studied areas were lower than the WHO permissible limits for PTEs in soil. Among the fruits and vegetables, Bitter leaf had highest PTE from Eke Awka followed by banana, fluted pumpkin, water leaf and onion. Fluted pumpkin had the highest PTE content from Omor followed by watermelon, water leaf, onion and cucumber, while water leaf had the highest metal concentration from Atani followed by bitter leaf, fluted pumpkin, cucumber, lettuce and carrot. Health risk assessment showed that hazard index (HI) in decreasing order was Eke – Awka market > Omor market > Atani market across all fruits and vegetables, as adverse health effect is not expected. The present study recommends containment measures of potential toxic elements in soils and fruits/vegetables to prevent excessive accumulation in food value chain.
Health effects of air pollutant mixtures (volatile organic compounds, particulate matter, sulfur and nitrogen oxides) – a review of the literature
Authors: Fazakas Emese , Neamtiu Iulia A. , Gurzau Eugen S.
Published: March 2023

The health risks associated with individual air pollutant exposures have been studied and documented, but in real-life, the population is exposed to a multitude of different substances, designated as mixtures. A body of literature on air pollutants indicated that the next step in air pollution research is investigating pollutant mixtures and their potential impacts on health, as a risk assessment of individual air pollutants may actually underestimate the overall risks. This review aims to synthesize the health effects related to air pollutant mixtures containing selected pollutants such as: volatile organic compounds, particulate matter, sulfur and nitrogen oxides. For this review, the PubMed database was used to search for articles published within the last decade, and we included studies assessing the associations between air pollutant mixtures and health effects. The literature search was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A number of 110 studies were included in the review from which data on pollutant mixtures, health effects, methods used, and primary results were extracted. Our review emphasized that there are a relatively small number of studies addressing the health effects of air pollutants as mixtures and there is a gap in knowledge regarding the health effects associated with these mixtures. Studying the health effects of air pollutant mixtures is challenging due to the complexity of components that mixtures may contain, and the possible interactions these different components may have.
A bibliometric and visual analysis of social semiotics: development, hotspots, and trend directions
Authors: Xiao Han , Li Lei
Published: March 2023

Social semiotics is now widely regarded as one of the leading research areas. This study is the first attempt to present a holistic overview of social semiotics based on the data in the Web of Science core collection database from 2001 to 2020. The study investigates, among other issues, social semiotics’ publishing tendency, the most productive authors, countries, institutions, and hotspots. The results exhibit a steady rise in its publications and citations. The current analysis verifies the growing quantitative and qualitative research contributions and influences of this field. Furthermore, what the journals focus on are the innovative and contemporary themes, manifested predominantly in sign, multimodality, gender, experimental semiotics, advertising, culture, and social media, which involve a wide range of methodologies to make the research more acceptable and constructive. These results are expected to offer refreshing insights that inspire scholars in formulating scientific agendas and advising their research strategies, thereby facilitating substantial contributions to the domain.
Potential pharmacokinetic interactions in fixed-dose combinations of perindopril/indapamide/amlodipine compared with perindopril/indapamide and amlodipine in healthy Chinese volunteers
Authors: Gao Huitao , Liu Hongzhong , Zheng Xin , Cui Xinge , Bricout-Hennel Stephanie , Lucien Arnaud , Lauruol Pauline , Wang Yaqin , Wang Xue , Wang Hongyun , Rui Chen
Published: March 2023

S05590 is a fixed-dose combination of perindopril tert-butylamine 4 mg/indapamide 1.25 mg, and S06593 is a fixed-dose combination of perindopril arginine 5 mg/indapamide 1.25 mg/amlodipine 5 mg. The purpose of this study was to determine whether pharmacokinetic interactions exist among the components of S06593, compared with S05590 and amlodipine as reference drugs, in healthy Chinese male volunteers after a single oral administration under fasting conditions. A single-center, open-label, randomized, three-period, six-way crossover study was conducted. A total of 42 participants were enrolled and randomized to receive S05590 plus amlodipine, or S06593. The doses of perindopril were 3.34 mg in both S05590 and S06593, calculated as free acid. Blood samples were collected in each treatment period to determine the plasma concentrations of perindopril, indapamide and amlodipine, as well as perindoprilat, the main metabolite of perindopril. A total of 39 participants completed this study. The 90% confidence intervals of the geometric mean ratios of Cmax, AUC0-tand AUC0-∞for perindopril, perindoprilat, indapamide and amlodipine were all within 80.00–125.00%, thus indicating that S05590 plus amlodipine and S06593 were pharmacokinetically equivalent. During the study, only one serious emergent adverse event was reported, which was deemed not to be associated with the study drug. No serious treatment-associated adverse events were observed.
On the meaning of human life (neoclassical discourse)
Authors: P Menchikov Gennadiy
Published: March 2023

This article attempts to analyze the essence of the meaning of human life, its fundamental bases and reasons for its great importance, especially in the post-secular era.
Gone with the sound: critical perspectives on studying imaginability of American cinematic experience in the “sound” era, 1927-1935
Authors: Zhang Minglei
Published: March 2023

This article explores the human-technology relationship during the transition from silent films to sound films in American history and analyzes how this specific technology has influenced film audiences’ experiences. The author revisits the importance of human-centered technology and uses the term “imaginability” to describe the likelihood for both spontaneous bodily responses and technologically cultivated thinking activities inspired by cinematic engagement. The article challenges the discourse of technology as progress while focusing on the audiences’ experience during their cinematic engagement. The author's hypothesis is that sound film provides a linear channel of synchronization and hence produces restrictions on the audience’s imagination by limiting their temporal and spatial sensibilities. This synchronized sound technology offers a streamlined audiovisual reality through matching sounds and images in real-time, leading to a shortened processing of images, sounds, and their interconnections. The transitions between filmmaking and cinematic presenting have also revolutionized theater design, leading to the liminality that describes the state of transitioning under this circumstance led by sound technology, which generates metrics, measuring how fast and how thoroughly technology conquers an outdated society by enforcing innovations. The article focuses on the interplay between the spectatorship that addresses the condition of viewing films and the sound consciousness led by the synchronized sound system as applied to filmmaking. The analysis of imaginability becomes measurable, descriptive, and referential. The author suggests that the preservation and scrutiny of silent films are urgent and necessary to recognize the values of silent film production and the audience’s cinematic experience during the silent film era.
Rapid and efficient protocol for genomic DNA extraction from leaf tissues of coconut (Cocos nucifera L.)
Authors: Hari Prasad Shri , Shivaji Ajinath Lavale , Mathew Deepu
Published: March 2023

Good quality of the nucleic acid is the primary requisite for genomic research of crop plants. The presence of lipids, polysaccharides, polyphenols and protein molecules hinders downstream processes where genomic DNA has to be used as a template. Coconut leaf being highly fibrous and rich in all the secondary metabolites, isolation of good quality DNA remains a great challenge. Attempts to isolate the coconut DNA following the reported protocols are found not to yield DNA in the expected quality and quantity. A simple and fast approach for isolating the high-quality DNA from polysaccharides and polyphenolic-rich tissues of coconut is being detailed. As measured by its clear color, viscosity, and A260/280 ratio, the isolated DNA was devoid of polysaccharides, polyphenols, RNA, and other significant impurities. In addition to the detailing of the modifications made in the CTAB method, this paper discusses the major step-by-step improvements among the widely-followed DNA isolation protocols.
Foliar supplement of Boron limits yield gaps linked to reproductive growth and development hitches intomato (Lycopersicon esculentum)
Authors: Mbi Tabi Kingsley , Sighansenyuy Tienne Mbulav , Godswill Ntsomboh-Ntsefong , Lendzemo Tatah Eugene , Libert Brice Tonfack , Neh Acha Ache
Published: March 2023

Bloom drop and small size fruits are fundamental yield-limiting factors widening yield gap in tomato. This study was initiated with the objective to evaluate the contribution of boron combined with NPK in reducing the gap between potential and actual yield in a F1 Cobra 34 tomato hybrid. Treatment combinations consisted of two levels of NPK viz. (20:10:10) and (13:23:13) and three levels of boric acid (H3BO3) viz, 0.45mg.L-1, 0.90mg.L-1,1.80mg.L-1 denoted B1, B2, B3 respectively and an absolute control tested on reproductive growth of tomato. The experiment was an outdoor trial laid out in Randomized Complete Block Design including 3 blocks and7 treatment combinations repeated trice in each block. Same crop management practices were carried out in all experimental units. Parameters evaluated were mean number of flower /truss, mean number of flower drop, mean number of fruits at anthesis, mean number of fruit drop, mean number of fruits that reached harvestable maturity, mature fruit biometric characteristics, mean percentage of fruit cracks and shelf life. Data was analyzed using the SPSS version 17. Results revealed that, combined effect of H3BO3 and the two NPKs showed significant variations in all parameters evaluated compared to the control. However, optimum fruit yield related attributes and shelf life were obtained under H3BO3 at 1.80 mg.L-1 + NPK (13:23:13) treatment.
Growth and yield responses of potato (Solanum tuberosum L.) varieties to NPS blended fertilizer at Nedjo, Western Ethiopia
Authors: Dereje Amenu , Abebe Teshome , Haile Yemane , Belew Derbew , Pugh Hannah , Abbey Lord
Published: March 2023

Potato (Solanum tuberosum L.) is one of the major crops grown in several agroecological zones in Ethiopia but understudied. A field study was carried out to assess compound fertilizer, nitrogen-phosphorus-sulfur (NPS), effect on plant growth, yield and economic returns of three local potato varieties; namely, Menagesha, Gudane and Belete. Potato grown with the 150kg NPS/ha recorded the highest number of main stems and var. Belete had the most followed by var. Gudane and then var. Menagesha. An increase in NPS rate of application from 0 to 150 kg N/ha prolonged the time expected to attain 50% flowering from ca. 57 to ca. 69days. Variety Menagesha seemed to be early maturing compared to the other varieties. Consistently, the highest leaf tissue N, P and S concentrations were recorded by var. Belete, compared to vars Gudane and Menagesha. All the yield components increased significantly (P<0.05) when the rate of NPS application was increased stepwise to 150kg NPS/ha. Varieties Belete and Gudane were superior in having the highest marketable number of tubers compared to var. Menagesha. The partial budget analysis also showed the highest net benefit of 292,812 and 292,630 Birr/ha with marginal rate of return of 11798% and 15263% at 150kg NPS/ha for vars Belete and Gudane, respectively. This study must be repeated prior to recommendation while future research must analyze tuber biochemical quality in response to NPS blended fertilizer application.
Growth of Zea mays with endophytes of Zea mays spp mexicana (teocinte)
Authors: Dominguez Guider Marto , Ignacio-De la Cruz Juan Luis , Villegas Javier , Sanchez-Yañez Juan Manuel
Published: March 2023

The healthy growth of Zea mays demands nitrogenous and phosphorous fertilizers which, due to various problems in the soil, are not efficiently uptake by the roots of the plants. An alternative is the optimization of the NPF through the inoculation of the Z. mays seed with genera and species of endophytic fungi that promote plant growth of the type: Aspergillus niger, Gliocladium virens and Rhizopus oligosporus, which are effective in uptake of NPF reduced up to 50% for healthy plant growth. The objective of this research was to analyze the response Z. mays to A. niger, G. virens and R. oligosporus endophytesof teosinte with NPF reduced at 50%. The endophytic fungi were isolated from teosinte, and were individually inoculated in Z. mays with the NPF at 50%, through response variables: phenology and seedling biomass and flowering, the experimental data was analysed by ANOVA/Tukey (P<0.05). The results showed a positive response of Z. mays to G. virens registered 2.66g aerial dry weight (ADW), with R. oligosporus 1.70g of ADW and with A. niger 1.36g of ADW, values ​​with a statistical difference with the 0.50g of ADW of Z. mays without the endophytic fungi fed with the NPF at 100% (relative control). The foregoing supports that endophytic fungi from teosinte were able to positively interact with the root system of Z. mays, which allowed healthy growth despite reducing the doses of NPF up to 50%.
Bacillus thuringiensis and Micromonospora echinospora ongrowth of Phaseolus vulgaris
Authors: Velázquez-Medina Adilene , Ignacio De la Cruz Juan Luis , Sánchez-Yáñez Juan Manuel
Published: March 2023

The well-known bacteria genus called as Bacillus thuringiensis (Bt) is recognized for being used in the biological control of insect pests in agriculture. However, there is little information on the effect of Bt as a plant growth promoter and in interaction with Micromonospora echinopora, which, being an endophyte, could improve the response of Phaseolus vulgaris with NH4NO3 atreduced at 30%of common recommended without risk of affecting plant health or yield.The objective of this work was to analyze the response of P. vulgaris to Bt and M. echinospora with NH4NO3 at 30% of recommended dose. The experiment was conducted under a randomized block design, using the response variables: germination percentage, phenology and biomass. The experimental data were analyzed by ANOVA/Tukey HSD (P<0.05). In the results, it was found that B.thuringiensis induced in P. vulgaris a yield of 3.2Ton/Ha, while with M. echinospora 3.6Ton/Ha was reached, with NF reduced at 30%, while it was shown that B.thuringiensis improved the yield with M. echinospora with 4.0Ton /Ha, values with statistical difference compared to the 2.8 Ton/Ha of P. vulgaris without B.thuringiensis or M. echinospora used as relative control with 100% of the NF.Concluded that B. thuringiensis is not only useful in biological control but that it can be an excellent growth promoter that can be improved with M. echinospora, another option for the sustainable production of P. vulgaris.
Peristence behavior of Carbosulfan in Brinjal (Solanum melongena L.) Forage
Authors: Kamala I Merlin
Published: March 2023

I Merlin Kamala, Pesticide Toxicology Laboratory, Department of Agricultural Entomology, Tamil Nadu Agricultural University, Tamil Nadu - 641 003, India
Comparison between incorporation and stubble burning in an Humic Haploxerands Soil, Central Southern, Chile
Authors: E Marco Sandoval , S Carlos Ruiz , L Celerino Quezada , V Anita Pinilla
Published: March 2023

Stubble burning in Chile is a common practice used for the farmers but it causes nutrient losses, erosion and environmental pollution. An alternative to change this situation is the incorporation of crop residue to improve the soil quality. The objective of this research was to compare the effects of the incorporation of oat stubble and stubble burning on the chemical and physical properties in an Humic Haploxerands soil with crop rotation oat-wheat. A completely randomized experimental design was used by two treatments of incorporation and stubble burning with soil sampling at depths of 0-5, 5-10 and 10-20cm, with three replicates. The results showed that stubble incorporation represents an sustainable management alternative for the ash volcanic soils, that improve the soil pH, organic matter , potassium exchangeable , aggregates stability and soil porosity.
Quality indicators in nanche (Byrsonima crassifolia L.) fruits from Guerrero and Chiapas, Mexico
Authors: ME Jaimes-García , SV González-Zavaleta , DH Noriega-Cantú , J Pereyda-Hernández , S Guzmán-Coronado , R González-Mateos
Published: March 2023

The nanche (Byrsonima crassifolia) is a wild, rustic and native plant of Mexico and Central America, it adapts to different edaphic and climatic conditions. The objective was to analyze the quality indicators of the nanche fruits of Guerrero and Chiapas. Completely random samplings were carried out in three and two localities of Guerrero and Chiapas, respectively, in 5 trees of each locality, collecting 50fruits per tree. The indicators analyzed were: fruit weight, fruit density, polar and equatorial diameter, oBrix, firmness, epidermis thickness, pulp weight, seed weight, luminosity, chromaticity and hue. The correlation between equatorial diameter/weight and lightness/chroma with r 2 of 0.93. Localities of Guerrero with greater statistical difference: Paso del Real was in weight, equatorial diameter; epidermis and seed. The fruits from Las Tunas were outstanding in oBrix, hue and seed weight, and those from San Jerónimo, Guerrero, recorded higher fruit density and equatorial diameter. The localities of Chiapas with the greatest statistical differences: Santo Domingo in density, polar diameter, firmness and pulp, and Mixiquito in fruit density and luminosity. It is concluded that the quality indicators of the nanche fruits collected in Guerrero and Chiapas have a wide distribution and decision making in the selection of trees with specific characteristics.
Bioethical reflections on the end-of-life care
Authors: Eduardo de Siqueira José , Pessini Leo
Published: March 2023

The influence of technological pragmatism on the health care offered to critically ill patients, especially to those who are at the end of their lives, makes most of them end up in intensive care units. As we advocate a more humanized care for these people, we have prepared this article, which proposes a bioethical reflection on this matter. The text is divided into three parts: first, we discuss the reality of intensive care units in Brazil, based on the resolution of the Brazilian Federal Council of Medicine that regulates medical practice in intensive care units (Res. No. 2,156/16); second, we compare some aspects of the end-of-life care in 4 different countries: the USA, Japan, Italy and Brazil; finally we analyze euthanasia and assisted suicide, considering the technical and moral arguments presented by the American bioethicist Dr. Ezequiel Jonathan Emmanuel.
Staff nurses’ knowledge and attitude toward the concept of palliative care; Fatin Abusyriah RN BSN, abdelqader tayyem RN MSN questionnaire in a quaternary central hospital
Authors: Abusyriah BSN Fatin
Published: March 2023

Background: Palliative care sometimes perceived as hastening death or care delivered when active treatment failed. Nurses play a significant role in providing palliative care, but nurses, as well as other health care worker, need training about palliative care in order to achieve the intended goals. Aim: Explore the level of knowledge and attitude for the staff in King Saud Medical City (KSMC) Riyadh, Saudi Arabia toward palliative care. Method: A quantitative, cross-sectional study, 323 questionnaires were completed by the staff nurses covering medical-surgical, oncology and ICU. The tool consists of demographical data, Palliative Care Quiz for Nursing(PCQN), Frommlet Attitudes Toward Care of Dying (FATCOD) scale. Result: Poor knowledge toward palliative care founded among respondent PCQN mean total score (9.229) out of 20 SD (2.402) while Moderate attitude showed FATCOD mean total score 97.817 out of 150, SD (8.325). The area of assignments significantly affects the Knowledge of the staff; oncology unit reported higher score than the other areas, right knowledge has been shown, mean score for oncology unit (11.36), SD (3.53). Conclusion: Institutional strategy has to be implemented in the Middle East a to improve the palliative care services, palliative care nursing education has to be added to the undergraduate curricula in every nursing school, formal training and courses for post graduated nurses is necessary.
HIV/AIDS treatment, therapeutic strategy break throughs
Authors: Yong Lu Da , Ying Wu Hong , Ren Lu Ting
Published: March 2023

HIV/AIDS is currently an incurable viral infectious disease characterized with life-long drug utility. To overcome this therapeutic setback, fatal pathological processes and different therapeutic mechanisms must be explored in broader-range and greater dimension. In this Article, the major types of global HIV/AIDS therapeutic strategies (pharmaceutical modification, herbal medicine, novel drug targets, drug combination modality, animal models, palliative medicine, immune-stimulate for HIV latency as well as HIV clearance by biological-based therapy) are especially highlighted. After novel pathologic identifications and therapeutic evolution, HIV/AIDS therapeutic curability will be translated from animal model unto larger human population. In this biomedical scenario, major breakthroughs are looked forward.
Is serum albumin associated with prognostic in pediatric cancer patients?
Authors: Garófolo Adriana , Santos Maia Lemos Priscila dos
Published: March 2023

Serum albumin has been shown to be associated with clinical indicators in hospitalized patients. The objective was to study the association of serum albumin with clinical and nutritional indicators in pediatric cancer patients. A prospective cohort study carried out at Pediatric Oncology Institute of Federal University of São Paulo, Brazil. This study follows patients of 1 year old or above, during anti-cancer therapy, from January 2002 to January 2004, enrolled in an enteral nutritional protocol. Exclusion criteria were corticoid therapy, swallowing abnormalities and previous nutritional support. They received two types of oral supplement (industrialized formula and non-industrialized/homemade supplementation) and were followed for three weeks. Serum albumin was collected at admission of the nutritional protocol and after three weeks. The associations of the clinical and nutritional index with the decrease in serum albumin, serum albumin at admission and in week three and the differences between serum albumin in week zero and week three were studied. Fifty-four patients were analyzed. The analysis showed that episode of hospital stay and fever were associated with the decrease in serum albumin (p<0.05); and episode of hospital stay (p=0.05) and infection (p=0.02) with serum albumin in week three. Nutritional performance showed association with serum albumin: the higher albumin at admission of the protocol, the better nutritional outcome (p=0.02). Serum albumin at week three also influenced nutritional outcome: higher serum albumin was associated with reduced tube feeding indication (p=0.04). No association was found between serum albumin and anthropometric and body composition indexes. Albumin was more associated with clinical than nutritional index. This confirms adult studies that found association between albumin depletion and prognostic factors.
Ecological Status in and around Avadhan Industrial Area in Dhule District of Maharashtra, India
Authors: K Rathoure Ashok
Published: March 2023

The ecology and biodiversity of any area is the indicator of that particular area. Increasing population demanding more food and place to sustain, the biodiversity of area can be protected and conserved to better life and sustainability. Rapid industrialization is degrading the local biodiversity, hence it is strongly recommended that the industry set up should be at defined place or notified industrial area viz. MIDC (Maharashtra), GIDC (Gujarat), UPSIDC (Uttar Pradesh), etc.
Evaluation of the effectiveness of disinfection in dog shelter
Authors: Zigo František , Valkošáková Silvia , Ondrašovičová Silvia , Vargová Mária , Veszelits Laktičová Katarína
Published: March 2023

Cleaning and disinfection are among the most important tasks in shelters and an important link in the prevention and battle against infectious diseases. Inadequate cleaning and ineffective disinfection can spread the disease to animals in the surrounding pens or to people during their daily contact and care of the animals. It is important to follow the order of the individual steps performed during hygiene procedures and carry out subsequent control of their efficacy. The aim of this study was to evaluate the effectiveness of disinfection by means of swabs taken from selected surfaces in a dog shelter – Happy dog, located in eastern Slovakia. The surfaces were disinfected with Savo Prim contains active substance sodium hypochlorite and anionic surfactant. For good cleaning effect was added disinfectant in a ratio of 1:5 to hot water at a temperature of 50°C and sprayed under pressure of 50 Bar. The effectiveness of mechanical cleaning followed by disinfection was evaluated by microbiological swabs from watering and food bowls, wall and floor. Swabs were taken before and after mechanical cleaning and disinfection, from 10cm2 areas. The surface area was wiped with a sterile cotton swab, the swab was placed in a sterile tube with 10ml of sterile saline solution and 0.1ml from this mixture was applied to Endo agar and meat peptone agar. Swabbing of the disinfected surfaces showed a significant decrease in TCB (total count of bacteria) and CB (coliform bacteria). However, on the walls and floors were detected small count of TCB and CB after disinfection in comparison with the counts detected before cleaning but the number of indicator bacteria was below the recommended value. Based on these observations, we can evaluate the hygienic program with the disinfection performed in the shelter as sufficient.
Perinatal stroke and overlapping clinical presentation with HIE; studying practical diagnostic and management challenges through observational analysis of a single tertiary centre stroke patients
Authors: R Gupta , M Nafees , Ganado Claudia Chetcuti
Published: March 2023

Background: While therapeutic hypothermia is accepted as a standard of care for improving neurological outcome for HIE patients, evidence of its benefits for neonatal stroke is lacking. Neurological presentations of HIE and neonatal stroke can be difficult to distinguish and indeed neonatal stroke can coexist with HIE. Our observational analysis of a single centre cohort of stroke infants with MRI diagnosis highlights the practical challenges for distinguishing between the two groups and reaching an early definitive diagnosis to inform appropriate treatment. Methods: A retrospective cohort study of term neonates >37 weeks gestation born between May 2011 and April 2020 born at a specialised NICU network in the East of England with a principal diagnosis of neonatal stroke were obtained from Badgernet data. Results: 81% of infants (13/16) had sentinel events around delivery. 50% (8/16) of infants were therapeutically cooled. Of the 8 cooled infants only 3 (37%) of cooled infants fulfilled both Toby A and B criteria. Infants who received therapeutic hypothermia were more likely to present with early onset seizures (5/8) than infants who were not cooled (1/8) (p=0.019) . 6 of the 8 non-cooled infants compared to 2of the 8 cooled infants (p=0.03) had a higher seizure burden requiring escalation of antiepileptic medication to second line or need for maintenance treatment. Conclusion: Infants with neonatal stroke who present with early seizures are more likely to receive therapeutic hypothermia despite failure to fulfil both Toby A and B criteria. Early suspicion to inform management can be obtained more effectively from CFM while cranial ultrasound findings are generally non-specific. A normal CFM background, unilateral abnormal background and unilateral seizure activity are highly suggestive of neonatal stroke.
Optimization problem of attitude control of a spacecraft with bounded rotary energy using quaternions
Authors: Levskii Mikhail Valerevich
Published: March 2023

The original control problem of optimal reorientation from a state of rest to a state of rest is considered and solved. The control function is torque vector. Problem of optimal control is investigated in detail for statement when control is restricted and the used functional of optimality includes kinematical rotary energy and time of maneuver. For solving and synthesis of the optimal control program, the quaternion method and the Pontryagin’s maximum principle are applied. Analytic solution of the proposed problem is presented basing on the differential equation connecting the angular velocity vector and quaternion of spacecraft attitude. It is shown that a chosen criterion of optimality provides a turn of a spacecraft with rotation energy which does not exceed the required value. This property of proposed control increases safety of flight. The time-optimal problem was solved also. The control law is formulated in the form of an explicit dependence of the control variables on the phase coordinates. All key expressions and equations are written in quaternion form which is convenient for onboard realization and implementation. The analysis of the special control regime of the spacecraft was made. Analytical formulas were written for duration of acceleration and braking. For specific cases of spacecraft configurations (dynamically symmetric spacecraft and spheric-symmetrical spacecraft as particular cases), complete solution of optimal control problem in closed form is given. Numerical example and the results of mathematical simulation for spacecraft motion under optimal control are demonstrated. This data supplements the made theoretical descriptions, and illustrates the practical feasibility of the designed algorithm for controlling the spatial orientation of the spacecraft showing reorientation process in visual form.