bluuebunny/crossref_metadata_2025 huggingface dataset:
Geometry of geodesics through Busemann measures in directed last-passage percolation
Authors: Janjigian Christopher , Rassoul-Agha Firas , Seppäläinen Timo
Published: May 2022

We consider planar directed last-passage percolation on the square lattice with general i.i.d. weights and study the geometry of the full set of semi-infinite geodesics in a typical realization of the random environment. The structure of the geodesics is studied through the properties of the Busemann functions viewed as a stochastic process indexed by the asymptotic direction. Our results are further connected to the ergodic program for and stability properties of random Hamilton–Jacobi equations. In the exactly solvable exponential model, our results specialize to give the first complete characterization of the uniqueness and coalescence structure of the entire family of semi-infinite geodesics for any model of this type. Furthermore, we compute statistics of locations of instability, where we discover an unexpected connection to simple symmetric random walk.
On join irreducible $J$-trivial semigroups
Authors: Lee Edmond W.  H. , Rhodes John , Steinberg Benjamin
Published: May 2022

A pseudovariety of semigroups is
join irreducible
if, whenever it is contained in the complete join of some pseudovarieties, then it is contained in one of the pseudovarieties. A finite semigroup is
join irreducible
if it generates a join irreducible pseudovariety. New finite

\mathscr{J}

-trivial semigroups

\mathcal{C}_n

(

n \geq 2

) are exhibited with the property that, while each

\mathcal{C}_n

is not join irreducible, the monoid

\mathcal{C}_n^I

is join irreducible. The monoids

\mathcal{C}_n^I

are the first examples of join irreducible

\mathscr{J}

-trivial semigroups that generate pseudovarieties that are not self-dual. Several sufficient conditions are also established under which a finite semigroup is not join irreducible. Based on these results, join irreducible pseudovarieties generated by a

\mathscr{J}

-trivial semigroup of order up to six are completely described. It turns out that besides known examples and those generated by

\mathcal{C}_2^I

and its dual monoid, there are no further examples.
Inequalities involving $\pi(x)$
Authors: Alzer Horst , Kwong Man Kam , Sándor József
Published: May 2022

We present several inequalities involving the prime-counting function

\pi(x)

. Here, we give two examples of our results. We show that

\frac{16}{9} \pi(x)\pi(y)\leq \pi^2(x+y)

is valid for all integers

x,y\geq 2

. The constant factor

16/9

is the best possible. The special case

x=y

leads to

\frac{4}{3}\leq \frac{\pi(2x)}{\pi(x)} \quad (x=2,3,\ldots ),

where the lower bound

4/3

is sharp. This complements Landau’s well-known inequality

\frac{\pi(2x)}{\pi(x)}\leq 2 \quad (x=2,3,\ldots ).

Moreover, we prove that the inequality

\Bigl(2\frac{\pi(x+y)}{x+y}\Bigr)^s \leq \Bigl( \frac{\pi(x)}{x}\Bigr)^s + \Bigl(\frac{\pi(y)}{y}\Bigr)^s \quad (0< s\in \mathbb{R})

holds for all integers

x,y\geq 2

if and only if

s\leq s_0=0.94745\ldots.

Here,

s_0

is the only positive solution of

\Bigl( \frac{16}{7}\Bigr)^t -\Bigl( \frac{6}{5}\Bigr)^t=1.
Investigation of a human brucellosis outbreak in Douz, Tunisia, 2018
Authors: Charaa Nejib , Ghrab Rabaa , Ben Othman Aicha , Makhlouf Mohamed , Ltaief Hejer , Ben Alaya Nissaf , Chahed Mohamed
Published: May 2022

OBJECTIVES: In 2017, the incidence of human brucellosis in Tunisia was 9.8 per 100,000 population. In the Douz district, 2 cases were reported in March 2018. Prior to that date, the last indigenous cases to be reported in Douz had been in 2015. This study aimed to identify the source of this new contamination and recommend control interventions.METHODS: This case-control study included residents of Douz who presented with clinical symptoms of brucellosis and had a subsequent Wright test antibody titer ≥ 1/160. The controls were neighbors of the infected cases who had a negative Rose Bengal test. Univariate and multivariate analyses were performed to estimate the odds ratios of risk factors. Goats belonging to the cases and controls were actively screened.RESULTS: Twenty-five infected cases and 52 uninfected controls were enrolled. All infected cases had consumed goat milk and 92% had purchased it from the same breeder. Consumption of goat milk from this breeder (adjusted odds ratio [aOR], 30.78; 95% confidence interval [CI], 6.47 to 235.91) and overall consumption of raw goat milk (aOR, 14.84; 95% CI, 2.04 to 310.44) were independent risk factors for brucellosis. The breeder had 18 goats, 5 of which were smuggled from a neighboring country. Three of those goats were diagnosed with brucellosis.CONCLUSIONS: Consumption of raw milk from smuggled sick goats was the main risk factor in this outbreak. The sick goats were slaughtered and an education campaign was conducted. Vaccination, control of cross-border animal movements, and control of goat milk sales must be strengthened to prevent the spread of brucellosis in southwestern Tunisia.
Optimization of ultrasound-assisted extraction of phenolic compounds from fresh Moringa oleifera leaves with a response surface methodology and comparison with the Soxhlet extraction method
Authors: Thi Hoang Yen Nguyen , Pham Tan Quoc Le
Published: May 2022

ABSTRACT. The present study evaluated the optimum conditions of ultrasound-assisted extraction (UAE) and Soxhlet extraction (SE) of antioxidant capacities and total phenolics from fresh Moringa oleifera leaves, using the response surface methodology. Spectrophotometric method with Folin–Ciocalteu and 2,2-diphenyl-1-picrylhydrazyl (DPPH) reagents was used to determine the total phenolic content (TPC) and the antioxidant activity (AA), respectively. The four models obtained showed the non-linear and quadratic dependences of both measured responses (TPC and AA) which were influenced significantly by all control variables including the acetone solvent (70%, v/v) to solid (SS) ratio, extraction time, and extraction temperature of both extraction methods. Furthermore, at the same extraction temperature, the extraction efficacy of UAE was better than SE as significantly shorter extraction time, less extraction solvent, but higher bio-active content was experienced. The optimal UAE conditions included a SS ratio of 31:1 (mL/g), extraction time of 26 min, and extraction temperature of 59 oC, resulting in the maximum TPC (34.36 mg GAE/g dry weight, DW) and AA (491.9 µmol TE/g DW) in the extracts. In addition, the models proposed were considered to be accurate and reliable for predicting the TPC and AA of fresh M. oleifera leaf extract. The research findings also imply potential applications for ultra-sonication extraction to produce the extracts from fresh M. oleifera leaves for pharmaceutical industry as well as food technology.

 

KEY WORDS: Antioxidant activity, Herbal plant, Model, Polyphenols, RSM

 

Bull. Chem. Soc. Ethiop. 2022, 36(2), 261-275.                                                               

DOI: https://dx.doi.org/10.4314/bcse.v36i2.2
New analytical methods for the determination of ascorbic acid content in aqueous extracts of flesh, peel and seeds of pumpkin (Cucurbita maxima)
Authors: Hagos Mulu , Redi-Abshiro Mesfin , Singh Chandravanshi Bhagwan , Ele Yaya Estifanos
Published: May 2022

ABSTRACT. The main objective of this research was to develop a simple, rapid, cost-effective, and environmentally friendly methods for determining ascorbic acid in flesh, peel, and seeds of pumpkin. Ascorbic acid was extracted from the different parts of the pumpkin in water. The content of ascorbic acid in three parts of the pumpkin was determined using ATR-FTIR and UV-VIS methods. The ATR-FTIR method was validated to determine ascorbic acid at 1046 cm-1, and the results indicated a linear range of 5 to 50 g/L; R2, 0.999; LOD, 1.7 g/L; LOQ, 5.2 g/L; RSD, 0.09% to 0.65%, and %recovery of 95.86%. Ascorbic acid was also determined at 265 nm by the UV-VIS method that revealed a linear range of 1 to 12 mg/L; R2, 0.999; LOD, 0.25 mg/L; LOQ, 0.75 mg/L; RSD, 0.12% to 0.43%, and %recovery of 96.96%. Accordingly any of the two newly developed methods can easily be applied for quantitative determination of ascorbic acid in pumpkin flesh, peel, and seeds. Both methods yielded higher ascorbic acid content in pumpkin seeds than in pumpkin flesh and peel. Both ATR-FTIR and UV-VIS spectroscopic methods are green, low cost and rapid method. However, UV-VIS method showed higher sensitivity than the ATR-FTIR method.

 

KEY WORDS: Pumpkin, Cucurbita maxima, Ascorbic acid, ATR-FTIR spectroscopy, UV-VIS spectrophotometry

 

Bull. Chem. Soc. Ethiop. 2022, 36(2), 277-290.                                                            

DOI:https://dx.doi.org/10.4314/bcse.v36i2.3
Solid-phase extraction of folic acid from pharmaceutical formulations using modified magnetic iron oxide nanoparticles
Authors: Hadi Hind , Amer Rana
Published: May 2022

ABSTRACT. A new analytical approach was suggested for the extraction and determination of folic acid in pharmaceutical samples using solid-phase microextraction. Magnetic iron oxide nanoparticles modified with sodium dodecylbenzene sulfonate (Fe3O4@SDBS) were used for the adsorption of folic acid (FA) from an aqueous solution and determined spectrophotometrically at λmax of 365 nm. The chemical and physical conditions that may affect the efficiency of extraction were studied and optimized, such as the pH of the solution, surfactant and adsorbent amount, extraction time, and desorption factors. A good linearity range of 0.2-6 μg/mL with correlation coefficient higher than 0.999 and limit of detection of 0.08 μg/mL were obtained, in addition to high extraction efficiency of 98% and enrichment factor 15. The method exhibited good accuracy and precision with recoveries ranged 98-102% and intraday precisions of best than 3.5% at all concentrations. The method was successfully applied for the determination of folic acid in pharmaceutical samples within a limited separation time.

 

KEY WORDS: Folic acid, MNPs, Extraction, SDBS, Spectrophotometry, Solid phase extraction

 

Bull. Chem. Soc. Ethiop. 2022, 36(2), 291-302.                                                                

DOI: https://dx.doi.org/10.4314/bcse.v36i2.4
Performance analysis of two different sizes of wind turbine rotors based on Nigerian low wind regime
Authors: Kunya B.I. , Ahmed A.
Published: May 2022

Nigeria can reduce its level of dependency on fossil fuel by making use of wind energy which is an indigenous renewable energy source for electricity generation. For large energy generation, large wind turbine is more preferable over a wind farm of smaller wind turbine units that will generate the equivalent amount of energy because, there will be loss of energy due to transmission and generation system of every turbine unit of the wind farm while the larger turbine has only one transmission and generation units. However, smaller wind turbines are generally more efficient than the bigger ones in terms of wind energy conversion and they are therefore good for small power generation. In this research work the performance of two different sizes of small wind turbine rotors, a 4-metre rotor (D4-Rotor) and a 4/5-metre one (D4/5-Rotor) were studied at 6m/s wind speed using numerical method. The POINTWISE software is used for modelling the rotor blade and meshing the flow domain. The software used for the simulation is ANSYS 20 which uses finite volume method (FVM) of analysis for solving governing flow equations. From the result of performances, the D4/5-Rotor has higher power coefficient (0.2995) than that of D4-Rotor (0.237), and this indicate about 26 per cent performance improvement of the smaller rotor. Conclusively, smaller wind turbines are more efficient than the bigger ones in terms of wind energy conversion and they are therefore good for small power generation especially in low wind regime.
Power performance comparison analysis of FPGA using Riemann Definite Integral Equation Solver
Authors: Adamu M. , Audu A.I. , Ngene C.U.
Published: May 2022

Definite integral equation solvers were hitherto developed using software which take long time to generate results. The complexity of designs and verifications, due to advancement in calculus and linear algebra, data dependency in designs, and the need for parallelism in models, necessitated the need for faster, accurate, and reliable hardware-based solvers. This will reduce latency and excessive memory requirement in generating values of definite integrals. The Field Programmable Gate Array (FPGA)-Based Definite Integral Solver developed in this research is able to solve definite integral equations with less resource utilization (1.08% look up tables (LUT), 0.07% flip flops (FF), 10.81% digital signal processing (DSP) and 23.86% input-output (IO)) and hence minimum switching activities at lower power (Signals: 0.421W, Logic: 0.345W, Digital Signal Processing: 1.904W and Input/Output: 0.015W) that translates to fast and accurate results generation. The power and resource utilization evaluation on the solver and the performance comparison with similar works showed that excessive memory consumption and resource utilization has been reduced significantly by the design.
Hand washing hygiene, sanitation and sustainable development goals in Umuahia North Local Government Area, Abia State, Nigeria
Authors: Obianyo J. I. , Eboh S. , Ije I. , Ohazurike E.E. , Nwobia L.I.
Published: May 2022

study on practices of hand washing hygiene, sanitation and sustainable development goals (SDGs), was carried out in Umuahia North local government area of Abia state, Nigeria, to investigate the causes of outbreaks of health care-care associated infections (HCAIs). Questionnaires made up of 25 attributes were distributed to health care workers (HCWs) to elicit from them their perception of these practices in their units. Complete responses came from 63 respondents which represented 79.75% of questionnaires distributed. The 5-point Likert scale was used in measuring the relative impact indices (RIIs) of not observing health care rules. About 42 of the respondents (66.67%) fall within the low region of RII, 19 respondents (30.10%) belong to the moderate region of RII, while 2 respondents (3.33%) fall in high region of RII. Information from 96.77% of the respondents indicated that hand washing hygiene and sanitation is poorly practiced. Rank ordering of relative observance indices (ROIs) showed that of the 25 attributes used in the study, 16 fall in the principal negative variables (Type 3), 5 of the attributes fall in the moderately negative variables (Type 2), while 4 fall in the relatively acceptable variables (Type 1), evidencing that 84% of the attributes are poorly practiced by HCWs. This situation impacted on the achievement of SDG3 and SDG6. It is concluded that these are the reasons for outbreaks in the area and it is recommended that government should educate HCWs on the observed risk factors for poor adherence to recommended hand hygiene practices.
Selection of optimum process parameters for penetration depth improvement of welded mild steel joints
Authors: Uwoghiren F.O. , Etin-Osa E.C.
Published: May 2022

High and low heat input degrade weld and weaken bond of fabrications respectively resulting in poor mechanical properties and high failure rate. However, good penetration depth is important factor for quality weld of materials. The research examined various welds by central composite design and then analyzed by response surface methodology. The experiments were achieved using prepared 100 samples of mild steel welded plates measuring 6mm x 40mm x 80mm. The investigation was performed 20 times using 5 samples for each run and then the hardness was measured and analyzed. The results obtained show that the penetration depth terminating at the weld root favoured a high quality weld. The model produced numerical optimal solution of current 120amps, voltage 20volts and gas flow rate 12l/min will produce a welded structure having a penetration depth 5.510mm at a desirability value 95.7%.
Artemisinin-based antimalarial combination therapy amongst healthcare professionals in a tertiary facility in south-south Nigeria: preferences, tolerability, and cost considerations
Authors: Ayinbuomwan A.S. , Opadeyi A.O. , Isah A.O.
Published: May 2022

Background: Nigeria adopted the Artemisinin-Based Combination Therapy (ACT) as the mainstay of treating uncomplicated malaria in February 2005. However, the individual preferences for the use of these medicines by health care professionals (HCP) as distinct from their observed prescribing practices is largely unknown. This study determined the preferences, tolerability and cost of the ACTs among HCPin Benin-City.Methods: This descriptive cross-sectional study was conducted in the University of Benin Teaching Hospital, Benin-City, Nigeria. Consenting HCPs were recruited consecutively for the study. Semistructured questionnaires were administered to doctors, nurses and pharmacists in the hospital. Information obtained included demographics, treatment of malaria in the previous year, antimalarial medication preferences and tolerability as well as cost of ACT.Results: A total of 556 HCPs, 295 doctors (54.1%), nurses 200 (36.0%), pharmacists 61(11.0%) completed the questionnaire. In the previous year, 224 (75.9%) doctors, 153 (79.1%) nurses, and 48 (70.5%) pharmacists had treatment for malaria and self-medication was highest among doctors (228, 77.3%). Artemether-Lumenfantrine was the most preferred antimalarial used, 294 (52.8%); however, 1.6% used chloroquine sulphate and ACTs were perceived to be ineffective by 25.4%. Adverse effects were experienced by 167 (29.1%) resulting in 50 (9.0%) discontinuing their medication. Between 500 and 1500 Naira (~US$1-4) was expended on ACT by 66.3% of the staff, while 21.4% were concerned about the high cost of medications.Conclusion: This study highlights the use and preferences, self-medication practices, perceived lack of effectiveness and high cost of ACTs from a HCP perspective. There is an urgent need to address these concerns in view of adverse consequences as well as the likely possibility of its the impact on prescribingpractices.
Characteristics of fresh and frozen-thawed Uda ram semen extended with Oviplus®, egg yolk and coconut milk
Authors: Abba A. , Bamanga U.M. , Bukar M.M. , Maina V.A. , Mustapha A.R. , Waziri M.A. , Amin J.D. , Ribadu A.Y.
Published: May 2022

Semen characteristics of Uda sheep and the effects of the egg yolk and coconut milk-based extenders on the quality of semen preserved at 4 oC and -196 oC were evaluated. Semen was collected from six Uda rams using an electro-ejaculator twice a week for ten weeks. Fresh semen samples were pooled and analyzed macroscopically and microscopically. The pooled semen was divided into 2 aliquots. One aliquot was extended in OviPlus® and egg yolk. The second aliquot was extended with OviPlus® and coconut milk. Each of the aliquots was further subdivided into 2 parts and evaluated microscopically. One part was chilled at 4 oC and evaluated for the same parameters after extension at 24, 48 and 72 hours. Second part was loaded into 0.25 ml plastic straws for cryopreservation at -196 ℃ and analyzed after 24 hours. The post thaw spermatozoa motility, livability and morphological abnormalities were determined at 24, 48 and 72 hours. The motility and concentration of freshly collected Uda semen were 81.7 ± 1.7 % and 3.2 ± 0.3 ×109/ml respectively. After extension, the motility decreased significantly (P < 0.05) from 82 % at 3 hours to 17 % at 72. The percentage live spermatozoa of the chilled semen did not differ significantly (P > 0.05) between the two extenders. Post thaw spermatozoa motility and livability were significantly (P < 0.05) reduced. There were significant differences (P < 0.05) between the post-thaw proportions of morphological abnormalities, between semen preserved at 4 oC and the frozen-thawed semen. In conclusion, semen motility, livability, and morphological abnormalities of Uda ram are equally preserved in coconut milk and egg yolk-based extenders at 4 oC up to 24 hours post extension. However, semen motility and livability were significantly reduced in the Uda semen earlier cryopreserved at -196 oC after thawing.
Comparative biocompatibility studies of Kirschner wire, allogeneic and canine xenogeneic cadaveric bone tissue implants in rat model
Authors: Aliyu BS , Hassan AZ , Ochube G.E. , Umar B.N. , Muhammad S.T.
Published: May 2022

Pre-clinical safety or biocompatibility studies of newer biomaterials intended for clinical use are paramount in medical implant technology. The in vivo safety of rat (allogeneic) and dog (xenogeneic) cadaveric bone implants (CBI) in the present study were assessed through histological and haematological profiles. A total of 12 male Albino rats (average weight 120 g) divided into three groups (A, B & C) of four rats each was used. Rat (allogeneic) and dog (xenogeneic) cadaveric bone implants were surgically placed between the lateral and cranial vastus muscles (on the thigh) of the rats in groups B and C, respectively, while Kirschner wire/inert implants were used for group A and served as control. The rats were monitored for 30 days, and peripheral blood profiles, as well as tissue sections at intervals of 14 and 28 days, were harvested, studied and compared. Results showed that the overall performance of all groups of rats was good. There was marked cellular infiltration of myocytes in rats of groups B and C, and cartilage-like (hyaline) cells in group C at 14 and 28-days post-implantation, respectively. No significant alteration existed in the haemogram of all groups of rats except for the increased lymphocytes count observed in group B pre-implantation. In conclusion, canine CBI used in this study possess fairly excellent biocompatibility and osteoinductive potentials in the rat’s model. Therefore, having confirmed their relative in vivo safety and biocompatibility, further clinical trials involving the use of cadaveric bone tissues as good biomaterial for fabricating bone fixatives should be performed in higher animal models.
Progesterone profile of red Sokoto does treated with prostaglandin F2-alpha and progesterone sponges for clinical application
Authors: Bello A.A. , Voh Jr A.A. , Ogwu D. , Tekdek L.B.
Published: May 2022

Progesterone profiles of Red Sokoto does were evaluated for clinical application. Fifty-one Red Sokoto goats does were assigned into three groups: (a) prostaglandin F2-alpha (n = 17), and given double injection of prostaglandin F2-alpha at 12-days interval; (b) progesterone sponges (n = 17), and administered progesterone sponges, inserted for 12-days; and (c) control (n = 17), no treatment. Blood samples were collected from all groups from day 0 to 6, day 9, day 12 to 15, day 19, and day 21 to 23 for progesterone profile. Group A had four profiles: 1) does in luteal phase at first and second injections; 2) does in luteal phase at first injection but insensitive at second; 3) does in follicular phase at first injection but luteal phase at second; 4) does, insensitive at first and second injections. Group B profile were: 1) does in luteal phase at sponge insertion; 2) does in luteal phase with decreased progesterone concentration; 3) does in follicular phase at sponge insertion; 4) does with insensitive corpus luteum at sponge insertion. It was concluded that progesterone profile assisted in describing exhibitions and non-exhibitions of behavioural oestrus in Red Sokoto does.
Nhận dạng các tác động đến hiệu quả quản lý và sử dụng máy, thiết bị thi công tại các doanh nghiệp xây dựng trên địa bàn Thành phố Hồ Chí Minh
Authors: Long Nguyễn Lê Minh
Published: May 2022

Quản lý và sử dụng hiệu quả máy, thiết bị thi công sẽ góp phần đem lại hiệu quả sản xuất của doanh nghiệp, giúp quá trình thi công được đảm bảo tiến độ, an toàn lao động, giúp các doanh nghiệp xây dựng trên địa bàn Thành phố Hồ Chí Minh (TP.HCM) nói riêng và cả nước nói chung nâng cao năng lực, đủ khả năng đảm nhận thi công các công trình xây dựng lớn, mở ra cơ hội hợp tác thi công với các nhà thầu nước ngoài. Do đó, nghiên cứu này nhằm nhận dạng các tác động đến hiệu quả quản lý và sử dụng máy, thiết bị thi công tại các doanh nghiệp xây dựng trên địa bàn TP.HCM thông qua trình bày kết quả khảo sát và phân tích với 139 bảng câu hỏi đã được thu thập. Các kết quả của phân tích nhân tố khám phá (EFA) đã chỉ ra 05 nhóm nhân tố chính bao gồm: Triển khai an toàn lao động trong sử dụng thiết bị thi công; Năng lực quản lý và trách nhiệm của điều hành cấp cao; Công tác quản lý thiết bị; Bảo quản, bảo dưỡng, sửa chữa, thanh lý thiết bị; Quản lý vận hành đúng tính năng và có nhật trình sử dụng máy. Các bên liên quan có thể sử dụng kết quả của nghiên cứu này để nâng cao hiệu quả quản lý và sử dụng máy thiết bị thi công trong quá trình sản xuất tại các đơn vị.
Tính chất đột biến gene APOB và LDLR trên bệnh tăng cholesterol máu ở người Việt Nam
Authors: Phượng Trương Kim , Thy Đỗ Nguyễn Mai , Toàn Nguyễn Bảo , Thúy Lê Huyền Ái
Published: May 2022

Bệnh lý rối loạn tăng cholesterol máu ở dạng có tính chất gia đình (FH) với nguyên nhân là sự xuất hiện đột biến tác động đến chức năng của gene APOB và LDLR. Nghiên cứu phân tích đặc điểm phân tử tập trung ở vùng trình tự exon 26 gene APOB và exon 4 gene LDLR trên người bệnh tăng cholesterol máu ở Việt Nam, bằng phương pháp PCR kết hợp với giải trình tự. Trên bộ mẫu bệnh phẩm máu (37 mẫu), nghiên cứu ghi nhận tỷ lệ đột biến trên gene APOB là 32.42%, gene LDLR là 35.10%, đột biến xuất hiện đồng thời trên gene APOB và LDLR có tỷ lệ 10.81% trong 37 mẫu tăng cholesterol máu. Một số dạng biến thể mới, đặc trưng xuất hiện trên DNA bộ gen người bệnh tăng cholesterol máu ở Việt Nam, cụ thể là c.10550C>G (p.A3517G), c.10575C>A (p.S3525R) và c.10560C> (p.Y3520*) ở gene APOB; c.21038C>T (p.P171L), c.21001A>T (p.T159S) và insC376 (c.ins20903C) ở gene LDLR. Kết quả nghiên cứu là cơ sở khoa học thực tiễn, hỗ trợ phát triển công cụ sàng lọc, chẩn đoán sớm bệnh lý tăng choleslesterol máu - bệnh FH ở Việt Nam.
Bellis (fungisit)’in balıklarda total oksidan / antioksidan ve total sialik asit seviyeleri üzerine etkisi
Authors: MOHAMMED Omar Mahmood , DEVECİ Haci Ahmet , NUR Gökhan
Published: May 2022

Bu çalışmada tarım alanında yaygın olarak kullanılan bir fungisit olan Bellis’in Cyprinus carpio’da plazma total antioksidan seviye (TAS), total oksidan seviye (TOS) ve total sialik asit (TSA) seviyelerine etkisinin araştırılması amaçlandı. Her grupta 10 adet olmak üzere toplam 30 adet (250-300g) C. carpio kullanıldı. Balıklar kontrol grubu, Bellis I grubu (0.025 mg/L Bellis) ve Bellis II grubu (0.050 mgl/L Bellis) olarak 3 gruba ayrıldı. Bellis gruplarına 14 günlük fungisit uygulamasının ardından balıklardan kan örnekleri alınarak, plazmaları elde edildi. Elde edilen plazma örneklerinde TAS, TOS ve TSA seviyeleri ölçüldü. Çalışmada elde edilen bulgulara göre kontrol grubunda TAS seviyesinin Bellis-I ve Bellis-II grubuna göre istatistiki olarak anlamlı derecede (p
Televizyon Dizilerinin Ortadoğu’da İnşa Ettiği Türkiye İmajı: Afganistan Üzerine Bir Alan Araştırması
Authors: ÖZKAN RIGIDERAKHSHAN Hülya
Published: May 2022

Kültürel etkileşim ve uluslararası düzeyde ulusal algının inşa edilmesinde kitle iletişim araçları önemli bir rol oynamaktadır. Bu çalışmada, Ortadoğu ülkelerinde popüler hale gelen Türk televizyon dizilerinin inşa ettiği Türkiye algısı ve söz konusu dizilerin izlenme nedenleri araştırılmıştır. Ortadoğu ülkelerinden örneklem olarak seçilen Afganistan’dan izleyicilere dizilerin oluşturduğu kültürel etkileşimi ortaya koymak ve dizilerin inşa ettiği Türkiye algısını/imajını açığa çıkarmaya yönelik sorular yöneltilmiştir. İzleyici görüşlerinin niteliksel veriler elde etmek amacıyla yarı yapılandırılmış mülakat soruları aracılığı ile tespit edilmesi amaçlanmıştır. İzleyicilerin Türk televizyon dizilerini izleme alışkanlıkları, dizilerin izleyicileri nasıl, neden ve ne yönde etkilediği çözümlenmeye çalışılmıştır. Kullanımlar ve doyumlar yaklaşımı temel alınarak yapılan bu araştırmada, televizyon dizilerini izleyen 18 yaşından büyük Afganistanlı 22 katılımcı ile yüz yüze ve online görüşmeler gerçekleştirilmiştir. Ayrıca özellikle son 10 yıldır giderek artan bir izlenme oranına sahip olan televizyon dizilerinin potansiyel bir yumuşak güç̧ stratejisi oluşturmadaki rolüne odaklanılmıştır. Görüşmelerden elde edilen veriler televizyon dizilerinin Afganistanlı izleyiciler nezdinde diğer Ortadoğu ülkelerinden farklı bir Türkiye imajı inşa ettiğini ortaya koymaktadır. Osmanlı ve Selçuklu tarihini konu alan dizilere dair olumlu görüş bildirilirken; aşk, romantik komedi, dram dizilerinde yer verilen aile yapıları, kadın-erkek ilişkilerine yönelik ise olumsuz bir yaklaşım sergilendiği saptanmıştır.
Raising public awareness to break the chain of the spread of COVID-19 in Cibungur Village, Parungponteng District
Authors: Sidiq Fahmi
Published: May 2022

Corona virus or covid-19 is a viral infection that was discovered at the end of 2019 in the city of wuhan, China. The massive spread has made more than 900,000 Indonesians infected with COVID-19. Nevertheless, there are several ways that can be done to reduce the risk and prevent transmission, one of which is the implementation of Clean and Healthy Lifestyle (PHBS), the use of hand sanitizers and masks. Community service is carried out in Cibungur Village, Parungponteng District. Cibungur village is one of the vulnerable places in the transmission of COVID-19. This is because there are so many people from villages who work in urban areas, so the risk of spreading it is very vulnerable. Therefore, the University Pharmacy Study Program took the initiative to provide community service by providing hand sanitizers and masks as an effort to implement clean and healthy living behaviors, as well as efforts to break the COVID-19 chain.
Development of Writing Teaching Materials with a Contextual Approach of Public Junior High School (SMPN 1), Pinang City, South Labuhan Batu, Indonesia
Authors: Wahyuni Dewi , Risnawaty Risnawaty , Sutikno Sutikno , Kartolo Rahmat
Published: May 2022

Based on observations from interviews with Indonesian language and literature teachers at SMPN 1, Pinang City, South Labuhan Batu, Indonesia, it is known that students' writing skills still need to be improved. Only 60% of students who are able to write instructions properly and correctly, the rest still have difficulty in writing instructions. In this study, there are two categories of research data sources. First, the data source for the prototype needs of teaching materials consists of students and teachers. Second, the prototype validation data source that will assess the prototype of teaching materials writing instructions with a contextual approach. Sources of data needs prototype teaching materials in this study are students and teachers. Sources of prototype validation data that assess the product development of this research are teachers and expert lecturers. The main finding of this study is the average value given by three teachers and two experts on the prototype of teaching materials for writing instructions with a contextual approach, namely (1) aspects of material presentation of 69.79 included in the good category, (2) aspects of content /material of 79.17 is included in the good category, and (3) aspects of language and readability of 80.42 are included in the good category. After making improvements based on the results of assessments and suggestions by teachers and experts, the teaching materials write instructions with the Contextual after repair contains material on the meaning of writing instructions, characteristics that need to be considered in writing instructions, steps for writing instructions, examples of writing instructions, and effective sentences.
Tick abundance, diversity and pathogen data collected by the National Ecological Observatory Network
Authors: Paull Sara H. , Thibault Katherine M. , Benson Abigail L.
Published: May 2022

Cases of tick-borne diseases have been steadily increasing in the USA, owing in part to tick range expansion, land cover and associated host population changes, and habitat fragmentation. However, the relative importance of these and other potential drivers remain poorly understood within this complex disease system. Ticks are ectotherms with multi-host lifecycles, which makes them sensitive to changes in the physical environment and the ecological community. Here, we describe data collected by the National Ecological Observatory Network on tick abundance, diversity and pathogen infection. Ticks are collected using drag or flag methods multiple times in a growing season at 46 terrestrial sites across the USA. Ticks are identified and enumerated by a professional taxonomist, and a subset of nymphs are PCR-tested for various tick-borne pathogens. These data will enable multiscale analyses to better understand how drivers of tick dynamics and pathogen prevalence may shift with climate or land-use change.
COVAC: A Blockchain-based COVID Testing and Vaccination Tracking System
Authors: Sulaiman Alromaih Malak , Mahdi Hassan Mohammed
Published: May 2022

Blockchain is an emerging technology based on a distributed digital ledger system. Decentralized trust is one of the key factors behind the blockchain-based system. The transparency of such a system is better than a conventional centralized ledger system. By using a blockchain-based transaction system, any business organization can harness key benefits like data integrity, confidentiality, and anonymity without involving any third party in control of the transactions. Since the blockchain is used in numerous applications, the horizon is expanding at an unprecedented pace. It was found that tracking COVID vaccination in a transparent and accountable way is an emerging need, especially after the pandemic outbreak around the world. The blockchain platform is a good match for such applications. In this study, a blockchain-based COVID-19 testing and vaccination tracking system, called COVAC, has been designed to manage the COVID testing and vaccination process for local organizations. The “Prototype Software Development" approach was used to determine the system requirements according to the practical knowledge obtained through the vaccine monitoring and screening tests process and then communicated with local healthcare facilities to determine whether these requirements were satisfied. The blockchain-based implementation ensured the system transparency, integrity, and security of data on COVID-19 testing and vaccination
Polytechnic Management Information System For Academic Service Quality Improvement (Analytical Descriptive at the Study Program Level at the Bandung State Polytechnic)
Authors: Siswoyo Siswoyo , Sanusi Achmad , Iriantara Yosal , Nurjaman Ujang
Published: May 2022

The Management Information System (MIS) in Higher Vocational Education such as Polytechnics functions to coordinate and monitor the planning, implementation, and evaluation of education activities, especially at the study program level. The current MIS serves BAAK’s data and information needs, reporting for internal management and providing PD-DIKTI Database. MIS has not fully served the needs of internal customers. The aim of this research is to describe in depth the process of planning and evaluating MIS at the study program level. This research is limited to MIS academic services and support preparation for study program’s accreditation of BAN-PT. The theoretical study is supported by theological foundation of Al Qur’an and Hadits, the philosophical constructivism and the theory of Total Quality of Management (TQM). This research uses a qualitative descriptive approach, explore deeply into the data and information needs for students, lecturers, study program, and BAAK. The informant involved internal Polban namely BAAK’s person, head of department and study program, lecturers and students, reviewing statute documents, strategic plans, academic regulation, laws and government’s regulations related to polytechnic’s management. This research reveals that the current MIS program is not based on customer’s needs yet by paying attention to business processes in planning, implementing, and evaluating teaching and learning process. MIS in implemented stage solely for BAAK needs, does not yet serve data needs for study programs, lecturers and students, including not yet supports the preparations of program study’s accreditation by BAN-PT. Customers are still difficult to get the information needed. The results of the evaluation show that there is a gap between data and information due to several inhibiting factors and a management system that is not yet based on complete data. The novelty of this research is MIS which is integrated with the current management system. MIS is designed comprehensively, not partially on project based. The conclusion is that the MIS program must be designed in the form of grand design that maps all data and information needs for internal and external customers which is customers oriented. MIS implantation will be successful if it is supported by socialization for customers, integrating existing MISs including databases and online communication networks, adequacy of MIS infrastructure include hardware, bandwidth capacity and high speed accessibility of information.
Isolation Of Chitosan From Cuttlefish Bones
Authors: Ningrum Siti Rahmi , Sinaga Siti Morin , Harahap Urip
Published: May 2022

One of the potential natural resources in Indonesia is the abundance of natural resources in the marine sector. The survey results show that the sale of cuttlefish in the market indicates that the demand for cuttlefish is very high. Cuttlefish is a type of marine animal that is widely consumed by the public because of its very high protein content, but the part used from this cuttlefish is the meat, while the squid bones are discarded. Cuttlefish bone is one of the natural ingredients that contains chitin, and when the isolation process is carried out with the stages of deproteinization, demineralization, and deacetylation, it can produce chitosan compounds. The aim of the study was to isolate chitosan from cuttlefish bones. Isolation of chitosan includes 3 basic stages, namely deproteinization, demineralization, and deacetylation. Then the characteristics of chitosan from cuttlefish bones are analyzed, namely water content analysis, ash content, protein content, ninhydrin test, and FT-IR characteristics. The results of characteristic testing of 8.04% water content, 1.73% ash content, and 4.8% protein content, ninhydrin test results showed that cuttlefish bone chitosan had an amine group, and FT-IR results showed that the absorption bands of C-O and C-N groups. The conclusion of this study shows that chitosan can be isolated from cuttlefish bones.
Operational Optimization Of A Potable Water Refilling Station
Authors: B. Muyot Norma , Sheena R. Saflor Charmine
Published: May 2022

This is study which focused on the determination of the coastal water quality, of the Aroma Beach, a strip of gray sand which stretches more than one kilometer and  located in San Jose, Occidental Mindoro. To determine water quality,  water samples were taken monthly from  February 2019 to May 2019 and subjected to analysis for pH, DO, temperature and oil and grease. Microbiological tests include determination of total coliform and fecal coliform measured in terms of most probable number per 100ml of the water sampled. Results of the study indicate that the coastal waters at Aroma Beach is safe for contact swimming and other recreational activities, however, values of its oil and grease have exceeded the maximum concentration slightly exceeded the DENR threshold for this pollutant.
University Foreign Language Teachers’ Perceptions of Professor-Student Rapport: A Hybrid Qualitative Study
Authors: Roshanbin Maryam , Nushi Mus , Abolhassani Zahra
Published: May 2022

Research has shown a consensus that positive professor-student relationship makes meaningful contributions to academic outcomes such as faculty effectiveness, increased motivation, enhanced learning, and excellent teaching. Employing a qualitative research design, the authors of this study examine the conceptualization of one specific aspect of faculty-student relationship; namely, rapport, which they believe is particularly salient in college classrooms characterized by effective teaching and a positive interpersonal climate. The data were collected through in-depth interviews with 26 Iranian foreign language professors who were selected through snowball sampling. A hybrid thematic analysis of the data revealed two core themes of rapport antecedents: (1) connectedness, and (2) professionalism and professorial ethics. The two themes and their sub-themes will be elaborated upon in this article. The article concludes by discussing the purposeful insights into the antecedents of rapport to provide concrete aspirational advice on how to potentially improve the higher education process.
The Process of Collaboration in Regulating Street Vendors in Bandung City
Authors: Kurniadi Kurniadi , Sumarna Ema
Published: May 2022

The development of the city of Bandung, as a service and trade centre in the province of West Java, Indonesia, is experiencing problems with the complexity of urban planning, including congestion and a slum environment, one of which is street vendors (abbreviated in Indonesian as Pedagang Kaki Lima/PKL). Street vendors in the city of Bandung grow and develop, followed by process of changing economic and social characteristics. Street vendors, basically the informal sector, are slowly shifting as if to become the formal sector with considerable capital support and more robust economic and social networks. On the one hand, the existence of street vendors acts as a driving force for the small-scale urban economy, but on the other hand, it appears as a cause of urban chaos. To overcome this problem, the Bandung City Government, through a special task force (which in Indonesian is called Satgasus PKL), involves street vendors associations to work together in structuring street vendors in Bandung City. This study aims to explain how the task force as a policy maker provides space for street vendors as beneficiaries by collaborating to solve urban problems and obstacles and challenges. The indicator used is the collaboration process between organizations by Huxham and Sev Vangen (1996). There are six processes: managing aims, compromise, communication, democracy and equality, power and trust, determination, commitment, and stamina. This study uses qualitative methods obtained through observation, literature review, and in-depth interviews. The results show that the open public space has not been optimally utilized by the task force and street vendors to solve the problem of structuring street vendors in the city of Bandung. Due to differences in motivation and orientation in structuring objectives, the dominance of the task force in the division of roles, communication barriers, distrust between the two parties, and low endurance to continue to collaborate.
A STUDY ON MAPPING SPATIAL PERCEPTION: THE CASE OF TARSUS
Authors: DUYMUŞ Halil , ALTUNKASA M. Faruk
Published: May 2022

Spatial perception is one of the main determinants of the relationship between people and space. People adopt the place they live in and assign a meaning to it or vice versa. The direction of behavior is determined by the positive or negative impressions of the person in a place. For this reason, parameters based on the cognitive processes of spatial perception are also used in the evaluation of the quality of the space. How urban space is perceived also guides urban planning and design studies. For this, it is important to know how the urban space is organized in the mental map of individuals and what effect it has on people. Based on this idea, it is aimed to obtain base maps that can be used for urban planning and design studies in this study. The study was carried out in the historical center of the city of Tarsus and its surroundings. In the first stage of the study, the perceptual values of the historical city center and its surrounding structures, open spaces and green spaces were mathematically revealed. At this stage, where experts were decisive, four Gestalt principles (similarity, proximity, closure and continuity) were used. In the second stage, it was tried to transform the perception values into perceptual maps in the GIS environment. Thus, base maps that can be used in urban planning and design studies have been obtained. Perceptual values in the base maps were found to be quite different from each other in terms of structures, open spaces and green spaces. The main reason for this result has been accepted that the elements that do not reflect spatial knowledge and experiences affect the integrity of perception by taking place in the historical city center over time. When the base maps are interpreted, it becomes clear that it is important to ensure spatial integrity and continuity by prioritizing spatial knowledge and historical experiences in urban planning and design activities in the historical city center and its surroundings.
MUSEUMS IN THE POST-DIGITAL AGE: CREATIVE EXPERIENCE DESIGN AND CRITICAL PERSPECTIVE
Authors: VARGÜN Özlem
Published: May 2022

While technological developments and innovations in museums are reflected in the forms of exhibition and presentation, the post-digital age evolved into a more human-oriented design experience in the periods. The purpose of this article; The aim of this study is to evaluate the use of technology towards experience designs in the Post-Digital Age, the methods of use of technologies, the contributions they provide, and the problems that arise in the methods of use of these technologies. As a research method, a literature review was made, the use of technology and design in museums was researched, the data obtained were reinterpreted with the descriptive method and findings were reached. According to the findings obtained, It has been seen that experience designs have increased in museums, and this has been effective in entertainment, curiosity and learning. It has been observed that the audience, which uses VR technologies and witnesses history, becomes free in the process of subjectivation. While virtual reality technologies enable us to witness history with an interesting and exciting experience, it has been seen that there may be problems in its editing. These; The dominance of today’s value judgments, the transformation of virtual reality into hyperreality or anachronism, the new reality of homotopic spaces in the re-editing of heterotopic spaces, the uncertainty about which story should be written and how from whose perspective, and virtual heritage inflation.
Vulnerability A Critical Tool for Conviviality-Inequality Studies
Authors: Teixeira Mariana
Published: May 2022

The aim of this working paper is to foster the concept of “vulnerability” as a critical tool for social theory in general and conviviality-inequality studies in particular. First, to clarify the concept, an analytical distinction is established between vulnerability as either an experiential structure shared by all persons (constitutive vulnerability) or as historical social injustice that detrimentally impacts some more than others (contingent vulnerability). The paper then explores the contrast between approaches to epistemic injustice theory and standpoint epistemology as two opposing views with regard to the political and epistemic potential of vulnerability. From this contrast, finally, a critique of one-sided conceptions shows us that, for vulnerability to have a productive and critical use, it must be grasped as fraught with ambiguity, implying both a contingent risk of subjection and a constitutive opening to otherness. It is this ambiguity that makes vulnerability a useful conceptual tool for grasping conviviality as inextricably connected to inequality