bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification and verification of potential piRNAs from domesticated yak testis
Authors: Gong Jishang , Zhang Quanwei , Wang Qi , Ma Youji , Du Jiaxiang , Zhang Yong , Zhao Xingxu
Published: November 2017

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PIWI-interacting RNAs (piRNA) are small non-coding RNA molecules expressed in animal germ cells that interact with PIWI family proteins to form RNA- protein complexes involved in epigenetic and post- transcriptional gene silencing of retrotransposons and other genetic elements in germ line cells, including reproductive stem cell self- sustainment, differentiation, meiosis and spermatogenesis. In the present study, weperformed high- throughput sequencing of piRNAs in testis samples from yaks in different stages of sexual maturity. Deep sequencing of the small RNAs (18 to 40 nt in length)yielded 4,900,538 unique reads from a total of 53,035,635 reads. We identified yak small RNAs (18- 30 nt) and performed functional characterization. Yak small RNAs showed a bimodal length distribution, with two peaks at 22 nt and >28 nt. More than 80% of the 3,106,033 putative piRNAs were mapped to 4,637 piRNA- producing genomic clusters using RPKM. 6,388 candidate piRNAs were identified from clean reads and the annotations were compared with the yak reference genome repeat region. Integrated network analysis suggested that some differentially expressed genes were involved in spermatogenesis through ECM-receptor interaction, and PI3K-Akt signaling pathways. Our data provide novel insights into the molecular expression and regulation similarities and diversities in spermatogenesis and testicular development in yaks at different stages of sexual maturity.
Penalaran Istiṣlāḥī dalam Kajian Fikih Kontemporer: Studi Kasus Fatwa Hukum Imunisasi di Aceh
Authors: Mubarrak Husni
Published: November 2017

This article discusses the use of istiṣlāḥi reasoning to answer the contemporary problem such as the MPU's Decree (Majelis Permusyawaratan Ulama) in Aceh on immunization.The reasoning of Islamic law often used to answer contemporary problems is the istiṣlāḥi reasoning. Although thei stiṣlāḥiy reasoning is more flexible in explaining the law of contemporary issues, but in the process of law enforcement, it must be assisted with other disciplines. As a result, the legal considerations are decided more accurately and scientifically to avoid any form of arbitrariness (authoritarian) in producing Islamic law. DOI: 10.15408/ajis.v17i1.6225
Polenblut. Images of Poland and the Poles in German operetta
Authors: Golianek Ryszard Daniel
Published: November 2017

Among the wealth of German operettas, an important place is occupied by works referring to Polish subjects in their plots, or featuring Polish characters. The moral judgments passed on the persons of the drama frequently reveal generalisations concerning large communities or even entire nations. At the present stage of research, I can confirm the existence of about a dozen German operettas containing Polish motives. For my analysis, I have selected three operettas: Polnische Wirtschaft, Polenblut and Die blaue Mazur, composed in more or less the same period – the 1910s. An analysis of characters and topics recurring in these operettas proves that certain prejudices and stereotypes play a major role in the construction of events and the characterisation of dramatis personae. An important role in the creation of national stereotypes is also played by musical categories associated with Polish culture, mainly national dances – the krakowiak and the mazur. The three stage works discussed in this paper, created in a period of historical transformation associated with Poland’s rebirth as an independent country, appear to offer excellent arguments in the ongoing debate on the role of national stereotypes in communication between neighbouring nations.
Karl Goldmark and Czech national opera: The final operas of Antonín Dvořák and Zdeněk Fibich
Authors: Kopecký Jiří
Published: November 2017

If Bedřich Smetana is thought to be the father of Czech national opera, Antonín Dvořák and Zdeněk Fibich would be his sons. Czech critics as well as the public expected that Smetana’s successors would bring Czech opera to international recognition. Dvořák and Fibich gave increased attention to opera composition during the 1890s and the beginning of the twentieth century. They both crowned their achievements with monumental operas on subjects with historical settings: Fibich’s The Fall of Arkona (1900) and Dvořák‘s Armida (1904). The reason for this apparent coincidence was, in part, that these works were written after Wagner’s operas and before the operatic successes of Richard Strauss, when it was possible to devise free combinations of symphonically composed scenes, arioso-like vocal lines influenced by verismo, and the dramaturgical effects of grand opera. As a praised model for successful historical opera might have served Karl Goldmark’s famous work Die Königin von Saba, especially in the case of Fibich’s last opera, which was explicitly compared with Goldmark’s opera. Operas on historical subjects form a little-known part of the works of Czech composers, but they extend from Smetana’s piece The Brandenburgers in Bohemia through the late operas of Dvořák and Fibich to Janáček’s two-part opera The Excursions of Mr Brouček. It is a line of operas that present an unforgettable counterpart to many successful Czech theatrical compositions – representative operas and intimate tragedies, comic operas and fairy tales, generally written on subjects from Czech villages and mythology, including Smetana’s Bartered Bride and Libuše, Fibich’s The Tempest and Šárka, Dvořák’s Jakobín, Kate and the Devil and Rusalka, Josef Bohuslav Foerster’s Eva, as well as Leoš Janáček’s Jenůfa.
Liszt’s Hungaro-European synthesis comments relating to the cultural-historical context of The Three Kings march of the Christus oratorio
Authors: Kovács Imre
Published: November 2017

It is evident that The Three Kings march of the Christus oratorio by Liszt is a verbunkos associated with the Eastern identity of Hungarians. What message did Liszt, who used musical motifs very consciously, wish to convey to the people of his time? I will approach the question not from a musicological aspect, but in the form of a cultural-studies type research. On the basis of the studies of Jácint Rónay and János Erdélyi dealing with national characterology, I wish to highlight how the Hungarian national identity and the myth of Eastern origin were related. I shall also examine in my paper paintings that bear close connection with the piece in question. Among these, Adoration of the Magi by Stephan Lochner is of vital importance, as according to the biographer of Liszt, Lina Ramann, it was the inspirational source of the movement in question of the Christus oratorio. The study attempts to find an answer to the relationship between the Lochner painting and The Three Kings march as well; and we shall see that it is also related to the question of the Eastern identity of the Hungarians.
Ottoman legacy and Oriental Self in Serbian opera
Authors: Marković Tatjana
Published: November 2017

Serbia was an Ottoman province for almost four centuries; after some rebellions, the First and Second Uprising, she received the status of autonomous principality in 1830, and became independent in 1878. Due to the historical and cultural circumstances, the first stage music form was komad s pevanjem (theater play with music numbers), following with the first operas only at the beginning of the twentieth century. Contrary to the usual practice to depict “golden age” of medieval national past, like in many other traditions of national opera, the earliest Serbian operas were dedicated to the recent past and coexistence with Ottomans. Thus the operas Na uranku (At dawn, 1904) by Stanislav Binički (1872–1942), Knez Ivo od Semberije (Prince Ivo of Semberia, 1911) by Isidor Bajić (1878–1915), both based on the libretti by the leading Serbian playwright Branislav Nušić, and also Zulumćar (The Hooligan, librettists: Svetozar Ćorović and Aleksa Šantić, 1927) by Petar Krstić (1877–1957), presented Serbia from the first decades of the nineteenth century. Later Serbian operas, among which is the most significant Koštana (1931, revised in 1940 and 1948) by Petar Konjović (1883–1970), composed after the theatre play under the same name by the author Borisav Stanković, shifts the focus of exoticism, presenting a life of a south-Serbian town in 1880. Local milieu of Vranje is depicted through tragic destiny of an enchanting beauty, a Roma singer Koštana, whose exoticism is coming from her belonging to the undesirable minority. These operas show how the national identity was constructed – by libretto, music and iconography – through Oriental Self. The language (marked by numerous Turkish loan words), musical (self)presentation and visual image of the main characters of the operas are identity signifiers, which show continuity as well as perception of the Ottoman cultural imperial legacy.
A publicidade na dinâmica da pós-modernidade e seu impacto na função social e na função solidária da empresa
Authors: Rocha Guilherme Aperecido da , Santiago Mariana Ribeiro
Published: November 2017

O presente artigo analisa as funções da empresa na sociedade pós-moderna, o que demanda um estudo compatível sobre o processo de desenvolvimento proporcionado pela globalização. Para tanto, pesquisou-se os conceitos e distinções entre função social e solidária da empresa, bem como os impactos de tais idéias em matéria de publicidade. Em conclusão, observou-se que o sistema de regulamentação da publicidade no Brasil precisa ser rediscutido e, dessa vez, à luz da realidade pós-moderna, ao mesmo tempo em que a própria sociedade de consumo começa a apresentar métodos que tendem a forçar as empresas a rever suas práticas publicitárias. O método de abordagem utilizado na pesquisa foi o dialético jurídico, paralelamente aos métodos de pesquisa bibliográfico e documental, inclusive com recurso a encíclicas papais.
A transparência na administração pública, o combate à corrupção e os impactos no desenvolvimento
Authors: Blanchet Luiz Alberto , Azoia Viviane Taís
Published: November 2017

A corrupção constitui um fenômeno amplamente discutido na atualidade e, por isso, buscou-se identificar como a transparência, uma concepção que extrapola o simples caráter formal do princípio da publicidade e de observância obrigatória pela Administração Pública em grande parte dos governos ao redor do mundo, pode auxiliar, juntamente com outros instrumentos, no combate à corrupção sistemática. Isso se dá, visto que a corrupção hoje é aceita como um dos mais desafiadores obstáculos ao desenvolvimento de um país, pois engessa estruturas públicas e compromete a estabilidade e integridade das instituições que representam a base da democracia e de seu exercício pelo acesso aos direitos constitucionalmente previstos. Para tanto, fez-se uma breve análise de ordem teórica do arcabouço jurídico e sociológico sobre a corrupção e seus impactos na sociedade, bem como outra de natureza empírica, partindo de dados previamente elaborados em estudos já publicados. Com isso, ressalvadas as críticas, pode-se dizer positiva a assertiva que elenca inúmeros efeitos negativos da corrupção, comprometendo diretamente o sadio e sólido desenvolvimento do país, pois ela, de maneira direta ou indireta, conduz a um ambiente de menor prosperidade do Estado, intensifica a exploração desmedida de recursos naturais, afeta a confiança na justiça, compromete a democracia e a boa governança, dentre tantos outros efeitos nefastos.
DESARROLLO DE UNA HERRAMIENTA OBSERVACIONAL DE ANÁLISIS DE COMBATES EN TAEKWONDO
Authors: Pedroza Cabrera Francisco Javier
Published: November 2017

Abstract.DEVELOPMENT OF AN OBSERVATIONAL TOOL FOR COMBAT ANALYSIS IN TAEKWONDOThe practice of taekwondo has become popular especially since its inclusion as an Olympic sport in 2000. In México its practice has resulted in obtaining at least one medal in each of the Olympic editions. Despite this, the works in psychology that focus in its study are scarce and even today, it is lacking instruments that allow explaining the success during the combats. One way to approach to this lack, is the use of the observational methodology, since this implies a type of study of the behavior that allows to collect reliable data of the behavior moment to moment, this fact, in the study of the sport derives in a detailed analysis of the factors involved in the result of competition. It is precisely because of this that the present work seeks to show the development of a specific observational tool for the analysis of Taekwondo combats. The tool was validated by pairs of trained observers with a kappa index of 0.84 including fights from the sub13, sub15, sub17 and sub20 categories in official tournaments. The results show the variety of data thrown and the implications of such results in terms of the development of training strategies for athletes are discussed.Key words: Taekwondo, observational methodology, sport, evaluationResumen.La práctica del taekwondo ha ido popularizándose sobre todo a partir de su inclusión como deporte olímpico en el año 2000. En México en particular, el entrenamiento en este deporte de contacto, ha derivado en la obtención de al menos una medalla en cada una de las ediciones olímpicas. Pese a esto, los trabajos en psicología que se centran en su estudio son escasos y hasta el momento se carece de instrumentos que permitan explicar el éxito durante las contiendas. Una manera de abordar esta carencia es el uso de la metodología observacional, ya que esta constituye un tipo de estudio del comportamiento que permite recolectar datos confiables registrando el comportamiento momento a momento, lo que en el caso de la conducta deportiva deriva en un análisis detallado de los factores involucrados en el resultado final para el atleta. Es debido justo a esto que el presente trabajo busca mostrar el desarrollo de una herramienta observacional específica para el análisis de combates en Taekwondo. La herramienta fue validada por pares de observadores entrenados con un índice kappa de 0.84 tomando en cuenta combates de las categorías sub13, sub15, sub17 y sub20 en torneos oficiales. Los resultados muestran la variedad de datos arrojados y las implicaciones de dichos resultados en términos del desarrollo de estrategias de entrenamiento para deportistas son discutidas.Palabras Clave: Taekwondo, metodología observacional, deporte, evaluación
NUEVOS RECURSOS TECNOLÓGICOS PARA TRABAJAR EN UN AULA DE EDUCACIÓN INFANTIL: EL CUENTO INTERACTIVO CONSIDERADO UN RECURSO DE APRENDIZAJE
Authors: Celia Domínguez Juana , Aguilar-Parra José Manuel , Fernández-Campoy Juan Miguel , Lozano Segura Mª Carmen
Published: November 2017

Abstract.NEW TECHNOLOGICAL RESOURCES TO WORK IN A CLASSROOM OF PRE – SCHOOL EDUCATION: THE INTERACTIVE STORY IS CONSIDERED A LEARNING RESOURCE.Currently, the new Information and Communication Technologies (ICT) are considered a key resource for education. This concept is progressing and we have a new term: LCT (Learning and Communication Technologies). This communication analyzes some resources which can be used and integrated in classrooms of pre – school education, in particular the interactive story, because according to the current regulations, we must introduce it during this period. With the purpose of integrating technological resources in the school area, we must educate teachers to get technological competences, innovate and experiment in classrooms together with their student body.Key words: ICT, technological resources, pre – school education, interactive story.Resumen. Actualmente, las nuevas Tecnologías de la Información y Comunicación (TIC) se consideran un recurso clave para la enseñanza, de tal manera que este concepto está evolucionando y tenemos un nuevo término: TAC (Tecnologías del Aprendizaje y la Comunicación). Esta comunicación analiza algunos de los recursos que pueden ser utilizados e integrados en aulas de Educación Infantil, en concreto los cuentos interactivos, ya que según la normativa actual debemos introducirlas durante esta etapa. Con el fin de integrar los recursos tecnológicos en el ámbito escolar, se debe formar al profesorado para que adquiera competencias tecnológicas, innove y experimente en el aula junto a su alumnado.Palabras claves: TIC, recursos tecnológicos, Ed.Infantil, cuento interactivo.
INFLUENCIA DE LAS HABILIDADES MATEMÁTICAS BÁSICAS EN EL RENDIMIENTO POSTERIOR
Authors: Mercader Ruiz Jessica , Presentación Herrero Mª Jesús , Siegenthaler Hierro Rebeca
Published: November 2017

Abstract.INFLUENCE OF EARLY NUMERACY SKILLS ON LATER PERFORMANCEThe objective of this longitudinal study was to examine the predictive value of early numeracy skills of counting, logical operations and magnitude comparison abilities evaluated in Kindergarten on the formal and informal aspects of mathematical performance in 2nd grade of Primary School. The initial sample consisted of 209 preschoolers aged 5 to 6 years, 180 of whom were retested two years later. In Kindergarten, different tasks of the TEDI-MATH battery (Grégoire, Noël, & Van Nieuwenhoven, 2005) were applied, which evaluate counting skills (procedural and conceptual), logical operations (seriation, classification, conservation and inclusion) and magnitudes comparison abilities (symbolic and non-symbolic). Two years later, the TEMA-3 test (Gingsburg & Baroody, 2003) was administered to assess different aspects related to mathematical performance. The results showed that 5 of the 8 tasks applied in Kindergarten are able to predict the subsequent mathematical performance, with a special weight of the ability to manage verbal numerical sequence (procedural counting). The implications of these findings for psychoeducational research and practice are discussed.Keywords: longitudinal study, mathematical performance, counting, logical operations, comparison skills.Resumen.El objetivo del presente estudio longitudinal consistió en examinar el poder predictivo de las competencias matemáticas básicas de conteo, operaciones lógicas y habilidades de comparación de magnitudes evaluadas en Educación Infantil sobre los aspectos formales e informales del rendimiento matemático en 2º de Educación Primaria. La muestra inicial estuvo compuesta por 209 preescolares de 5 a 6 años, de los cuales 180 volvieron a ser evaluados dos años más tarde. En Educación Infantil, se aplicaron diferentes tareas de la batería TEDI-MATH (Grégoire, Noël, y Van Nieuwenhoven, 2005) que evalúan las habilidades de conteo (procedimental y conceptual), operaciones lógicas (seriación, clasificación, conservación e inclusión numérica) y comparación de magnitudes (simbólica y no-simbólica). Dos años más tarde, se administró la batería TEMA-3 (Gingsburg y Baroody, 2003) para evaluar diferentes aspectos relacionados con el rendimiento matemático. Los resultados mostraron que 5 de las 8 tareas aplicadas en Educación Infantil son capaces de predecir el rendimiento matemático posterior, con un especial peso de la habilidad para manejar la secuencia numérica verbal (conteo procedimental). Se comentan las implicaciones de estos hallazgos para la investigación y la práctica psicoeducativa.Palabras clave: estudio longitudinal, rendimiento matemático, conteo, operaciones lógicas, habilidades de comparación.
Utilisation of the natural potential of rural areas for social inclusion
Authors: Jakub Husak , Helena Hudeckova
Published: November 2017

The paper presents selected results of the sociological research focused on social inclusive activities that use and are located in the natural environment of rural areas. The paper is based on the contemporary form of the concept of a fully integrated modern society, and deals with the implementation of this concept within the strategy of social inclusion in both the European and Czech context. The authors have created, based on secondary research, a typology of social inclusive activities within Czech rural areas. Primary research, consisting of a questionnaire survey, was used to study the awareness of these issues among the rural population. Based on the selected results of both the primary and secondary research, the authors conclude that a possible path to social inclusion, is, alongside specific social services, social farming, which harmonizes the potential of the rural natural environment with the attitudes of the rural population (the actors and observers of social inclusive activities within their locality).The ongoing research is focused on monitoring barriers to the development of this business sector, which are crucial for the rural actors.
Безопасность жизнедеятельности в мегаполисе Москва
Authors: Бурцев Сергей Петрович
Published: November 2017

В статье рассматриваются проблемы, нарушающие нормальную жизнедеятельность жителей города Москва, обсуждаются возможные механизмы градоразрушения, ухудшения физического и психического здоровья москвичей. Анализируется информированность граждан по различным аспектам безопасности в мегаполисе и возможность использования социальных технологий предупреждения чрезвычайных ситуаций и их устранения.
Семья и карьера в жизни современной российской женщины
Authors: Ромашова Людмила Олеговна , Середа Екатерина Михайловна
Published: November 2017

Статья посвящена извечной проблеме выбора между семьей и карьерой современной молодой женщины в условиях России.  Рассматриваются проблемы совместимости профессиональной карьеры с семейными обязанностями, а также факторы, способствующие снижению семейных ценностей.
Международный студенческий юридический форум «Влияние революционных событий 1917 года на становление и развитие государства и права»
Authors: Сошникова Тамара Аркадьевна
Published: November 2017

В статье представлен обзор работы Международного студенческого юридического форума «Влияние революционных событий 1917 года на становление и развитие государства и права», который проходил в Московском гуманитарном университете 26–27 октября 2017 г.
Comparative study of ropivacaine alone versus ropivacaine with dexamethasone in supraclavicular brachial plexus block
Authors: Krishna Sampathi Shiva , Chandra G. Praveen , Chaithanya C. Krishna
Published: November 2017

Background: Brachial plexus block is often used either as an adjuvant to general anesthesia (GA) or as a sole anesthesia modality. Supraclavicular brachial plexus block is preferred for its rapid onset, reliable anesthesia and as a safe technique for any surgery in the upper extremity that does not involve the shoulder. We have attempted to undertake this study to compare the haemodynamic, sensory and motor effects of the anaesthetic effect of Ropivacaine alone and Ropivacaine along with Dexamethasone in Supraclavicular Brachial Block in upper limb surgery.Methods: The total duration of surgery was also comparable in both groups. The onset of the sensory and the motor block in bother the groups were similar to each other with no statistical difference, but there was a very high significance in the duration of both sensory and motor block within both the groups.Results: The total duration of surgery was also comparable in both groups. The onset of the sensory and the motor block in bother the groups were similar to each other with no statistical difference, but there was a very high significance in the duration of both sensory and motor block within both the groups.Conclusions: Dexamethasone added to ropivacaine in supraclavicular brachial block for upper limb surgery significantly shortens the onset time and prolongs the duration of sensory and motor blocks without producing sedation in patients.
A cross sectional study on prevalence of obesity among bus drivers of Metropolitan Transport Corporation Limited, Chennai
Authors: Singaravel Sasikaladevi S. , Kandaswamy Elayaraja K.
Published: November 2017

Background: The job of bus driving involves several health risks. Both individual behaviours and work environmental variables contribute to higher obesity prevalence and risk of excess weight gain in this occupational group. This study has been planned to study the prevalence of obesity among bus drivers and to make recommendations to prevent obesity among bus drivers. Methods: The study was planned among bus drivers of the bus depots of Metropolitan Transport Corporation Limited, Chennai between January 2014 and June 2014. The sample size was calculated based on the assumption where the prevalence was 50%. Considering Confidence level of 95%, absolute precision of 5% with 10% excess sampling to account for non- response, the sample size derived was 422. Multistage sampling method was used. The required information was obtained by means of validated questionnaire and also by anthropometric measurements. Results: The mean age of the respondents was 42.32yrs. 41% of respondents were overweight. 14.5% of the respondents were found to be obese. Of the obese 22.7% were in the age group of above 50 yrs. There was found to be a statistical significance between age and obesity with a chi square value of 13.60 and a p value of less than 0.001. Conclusions: There was a significant association between age and obesity among bus drivers. There was also vast scope to avoid health risk factors by routine exercise, having regular diet and rest. With the help of experts of yoga, meditation, physical educationist, gymnasium experts etc. the drivers may be given counselling as to how to maintain the body mass index.
AVALIAÇÃO SENSORIAL E VIABILIDADE COMERCIAL DE UM COOKIE ENRIQUECIDO COM Β-GLICANA
Authors: Babos Talita Regina , Abranches Monise Viana , Sales Regiane Lopes de , Barbosa Meire De Oliveira
Published: November 2017

A alimentação é uma necessidade básica e vital para a sobrevivência humana, e o desenvolvimento de produtos mais saudáveis é de grande importância. Nesse contexto, o objetivo desse trabalho foi desenvolver um biscoito tipo cookie rico em β-glicana proveniente do farelo de aveia e avaliar sua aceitação, bem como sua viabilidade comercial. Foram elaboradas duas receitas de cookies: uma sem adição de β-glicana (padrão) e outra com adição de 3% (p/p) de β-glicana (teste) proveniente da substituição parcial da farinha branca por farelo de aveia. A análise sensorial das preparações foi realizada por 30 provadores não treinados e utilizou-se a escala hedônica de nove pontos para os atributos “Cor”, “Textura”, “Sabor” e “Impressão global”. Para o teste de intenção de compra foi utilizada uma escala estruturada de cinco pontos, variando de "certamente compraria" a "certamente não compraria”. Em relação à composição química, o cookie teste apresentou menor valor calórico (305,6 Kcal/100g), menor percentual de carboidratos (42,6 g/100g), maior percentual de proteínas (9,8 g/100g), além de ser fonte de fibras (5,4 g/100g), em relação ao cookie padrão. A análise sensorial demonstrou que ambos os cookies foram aceitos, não apresentando diferença estatística (p<0,05). Quanto à intensão de compra a maioria dos provadores compraria o produto se o mesmo estivesse à venda. O produto obtido apresenta características de viabilidade comercial como um produto rico em fibras.
AVALIAÇÃO DAS CONDIÇÕES DE AERAÇÃO DO PRÉ-INÓCULO UTILIZADO NO CULTIVO DE BACTÉRIAS ÁCIDO LÁTICAS (BAL) EM MEIO LÍQUIDO
Authors: Sá Samara Aparecida Cardoso Alves de , Oliveira Júnior Simão Pedro de , Dores Milene Therezinha das , Visôtto Liliane Evangelista , Silva Camila Rocha da
Published: November 2017

As bactérias ácido láticas são de grande importância para a indústria alimentícia, pois promovem a acidificação do meio auxiliando na obtenção das características sensoriais de produtos fermentados e na conservação destes produtos por criar um meio inóspito para outros microrganismos. Este trabalho objetivou avaliar as condições de aeração para posterior padronização do pré-inóculo dos isolados de bactérias ácido láticas de queijo minas Minas artesanal. Foram realizados testes morfotinturial de gram e catalase para seleção dos isolados gram positivos, catalase negativos e no formato de cocos. Foram testadas diferentes proporções de aeração para obtenção do pré-inóculo e três concentrações iniciais com relação às proporções utilizadas. O crescimento e acidificação dos isolados foram verificados á 32ºC, 100 rpm, nos tempos de 12, 15 e 18 horas. Os isolados selecionados foram o ILC 4 e ILC23 apresentando características morfológicas desejadas. De acordo com análises realizadas no período médio de 18 horas e a uma concentração de 1%, houve um maior crescimento de bactérias ácido láticas para o isolado ILC 4. Já para o isolado ILC 23, seu maior crescimento foi a uma concentração de 1% do isolado e a um tempo de 15 horas de cultivo. Quanto a acidificação, a partir das 12 horas iniciais observou-se um declínio nos valores de pH para ambos os isolados. Portanto a determinação do perfil de acidificação e crescimento de bactérias ácido láticas são essenciais, pois podem ser utilizadas como culturas iniciadoras para elaboração de produtos lácteos visando sua maior conservação e obtenção de características sensoriais desejáveis.
Variáveis Psicológicas e Desempenho Acadêmico: Uma Análise Da Existência de Correlação Canônica
Authors: Neisse Anderson Cristiano , Hongyu Kuang
Published: November 2017

A análise multivariada é um conjunto de técnicas estatísticas que permite a análise e interpretação de conjuntos de dados de natureza quantitativa com grande número de variáveis de forma simplificada. Dentre o rol de técnicas encontra-se a análise de correlação canônica (ACC) que visa estabelecer estrutura de relação entre dois grupos de variáveis por meio de combinações lineares que maximizem a correlação entre ambos. O objetivo deste artigo foi utilizar a técnica de ACC para analisar a correlação entre três variáveis psicológicas e quatro variáveis de desempenho acadêmico
The paradox of efficiency in terms of energy needs of road transport in the European Union
Authors: Motowidlak Urszula
Published: November 2017

With quantitative and qualitative data, and knowing, at a glance, goal, it was an attempt to examine the relationship between the development of road transport and the efficiency of resource use. The analysis has shown that road transport now gained a special status in people’s daily lives. The increased mobility of European citizens caused the greatest responsibility for the transport of energy. This spite of improving the efficiency of these cars and freight transport growth. The projected continued growth of freight transport will contribute to the further changes in the structure of energy consumption by road transport. Despite the high growth rate of energy efficiency improvement of truck drives, the share of demand for fuel by those vehicles will increase in total fuel demand for road transport sector. At the same time the energy consumption of cars will reduce its share in total fuel needs transport. Improvmrnt of energy efficiency of passenger and truck will not offset the increase in demand for energy in road transport. The above regularities define a key challenge facing the transport system – meeting the ever growing demand for energy.
Bystander Prevention of Sexual and Dating Violence: An Experimental Evaluation of Online and In-Person Bystander Intervention Programs
Authors: Hines Denise A. , Palm Reed Kathleen M.
Published: November 2017

Rates of sexual violence (SV) and dating violence (DV) are high on college campuses; federal law mandates colleges provide SV/DV prevention programming to incoming students. Programs showing the strongest empirical support are bystander programs; however, their small group format makes it impractical to use them with large student bodies. In a pilot feasibility study, we compared in-person and e-intervention SV/DV bystander intervention programs and randomly assigned 562 students to one of the programs. Students completed measures of knowledge and attitudes at 3 points over 6 months. Both groups changed significantly in the expected direction on all measures, with no differences between groups in change over time. Results suggest that e-interventions may be a viable alternative to in-person SV/DV programs for meeting federal mandates.
Revealing ETC-1922159 Affected Unknown 3rd Order Combinations of DNA Repair & Genomic Stability Factor RAD51 Family, in Silico
Authors: sinha shriprakash
Published: November 2017

DNA repair helps in maintaining the proper and healthy functioning for the cells in the human body. Failure in DNA repair process can lead to aberrations as well as tumorous stages. There are various types of damages that a DNA can go through, one of which is the DNA double strand breaks (DSB) that can be repaired via homologous recombination (HR). RAD51 plays a central role in HR and has been implicated as a negative/poor prognostic marker for colorectal adenocarcinoma, with high expression in colorectal cancer. Mechanistically, RAD51AP1 facilitates RAD51 during the repairing process by binding with RAD51 via two DNA binding sites, thus helping in the D-loop formation in the HR process. Often, in biology, we are faced with the problem of exploring relevant unknown biological hypotheses in the form of myriads of combination of factors that might be affecting the pathway under certain conditions. For example, RAD51AP1-XRCC2 is one such 2nd order combination whose relation needs to be tested under the influence recently developed Porcupine-WNT inhibitor ETC-1922159. The x-ray repair cross complementing XRCC family is known to work as a mediator or stabilizer for RAD51 during the HR process. The inhibitor is known to suppress Porcupine and thus inhibit a range of oncogenes known to be directly or indirectly affected by the Wnts. In a recent unpublished work in bioRxiv, we had the opportunity to rank these unknown biological hypotheses for down regulated genes at 2nd order level after the drug was administered. The in silico observations showed that the combination of RAD51AP1-XRCC2 was assigned a relatively lower rank, thus validating the pipeline's efficacy with the confirmed wet lab experiment that indicate that both RAD51AP1 and XRCC2 were down regulated after treatment in cancer cells. Here, we take one step further by in silico analysis of the 3rd order combinations of RAD51-X-X & RAD51AP1-X-X (X can be known or unknown factor), from a range of 100 randomly picked down regulated genes after ETC-1922159 treatment. The pipeline uses the density based HSIC (Hibert Schmidth Information Criterion) sensitivity index with an rbf (radial basis function) kernel, which is known to be highly effective in sensitivity analysis. Various unknown/unexplored/untested RAD51/RAD51AP1 related 3rd order biological hypotheses emerge some of which are confirmed in wet lab, while others need to be tested.
A Survey of English Language Teaching in Higher Institutions of Learning in Kuala Lumpur Malaysia
Authors: Shulgina Tatiana , Sagaran Gopal
Published: November 2017

The aim of this study is to explore the extent of English language teaching in Higher Institutions of Malaysia and investigate the current changes, trends and challenges in this niche. A sample of 100 English learners from public and private institutions participated in this study. Analysis of the responses indicated that English language is remaining to be difficult to master, due to speaking environment, proficiency of the teachers and other factors. However, the Government is on the right direction to improve this situation by following Common European Framework of Reference of Languages. As any other system, it takes time to put into realization and start up the mechanism. This observation carries a pedagogical perspective and includes the overview of the general picture based on Private, Public and Stand Alone English educational institutions. This study has highlighted the practical importance of British Framework of English learning and suggests to focus on emphasis of the learning process instead of a result.
Application of Virus-Derived Small Interfering RNAs (vsiRNAs) in Rice Viruses with Insect Vectors, Especially Rice Grassy Stunt Virus
Authors: Arif Muhammad , Islam Saif Ul , Adnan Muhammad , Anwar Muhammad , Wu Zujian
Published: November 2017

Rice grassy stunt virus (RGSV) a member of Tenuivirus family, is very potent and destructive which effects rice crop in many countries, particularly China. Non coding RNAs have important functions in development and epigenetic regulation of gene expression in numerous organsisms. There is three type of small non coding RNAs have been found in eukaryotes, which are small interferring RNAs (siRNAs), microRNAs (miRNAs) and piwi interacting RNAs (piRNAs). Small RNAs (sRNAs) origination is from the infecting virus which is known as virus-derived small interfering RNAs (vsiRNAs), has responsibility for RNA silencing in plants. Virus-induced gene silencing (VIGS) is mainly dependent on RNA silencing (RNAi). Interestingly, RNA silencing happens in plants during viral infections. RNAi technique showed significant results in Nephotettix cincticeps. RNAi technique demonstrated the gene silencing of planthopper Nilaparvata lugens. The proteins P5, pcf4, Dnj, psn5, and pn6 act as potential movement proteins and serve as silencing suppressors for RGSV. VsiRNAs originate from dsRNA molecules which require Dicer-like (DCL) proteins, RNA dependent RNA polymerase (RdRP) proteins, and Argonaute (AGO) proteins. RdRP uses ssRNA for perfect RNA amplification process and can also be used for DCL dependent secondary vsiRNA formation. VSRs interfere with the movement of signals during silencing mechanism. Moreover, intercellular movement of viruses is facilitated by virus-encoded movement protein. RNAi is found in many eukaryotes which are related to transcriptional or post-transcriptional regulation by gene suppression. Transcription is bidirectional in ssDNA viruses which are originated from dsRNA molecules. In this review, we highlighted the biology of Rice grassy stunt virus and its insect vector and its silencing suppressors. This work will be helpful for plant virologists to understand the whole biogenesis mechanism for rice viruses especially RGSV.
Simulation and Planning Project Logistics Operations: A Case Study of Transportation Operation of Autoclave from Petkim Port to Gördes Building Site
Authors: Görçün Ömer Faruk
Published: November 2017

Project logistics is one of the specific logistics operations. Compared to other logistics operations, it needs more efficient planning and engineering applications in each operational process. On the other hand, each project logistics operation can be defined as tailor-made operations, since it has no similarity with other operations. Consequently, each project logistics operation should be planned and carried out according to its own conditions and parameters. This study focuses on the simulation of project logistics operations under the light of computerized applications from start to finish of the logistics operation. In this study, transportation operations of 600 tons of autoclave from the Petkim port to the Gördes building site were selected as a case study.
A Measure of Information Available for Prediction
Authors: Isomura Takuya
Published: November 2017

Mutual information between the brain state and the external world state represents the amount of information stored in the brain that is associated with the external world. On the other hand, surprise of sensory input indicates the unpredictability of the current input. In other words, this is a measure of prediction capability, and an upper bound of surprise is known as free energy. According to the free-energy principle (FEP), the brain continues to minimize free energy to perceive the external world. For animals to survive, prediction capability is considered more important than just memorizing information. In this study, the fact that free energy represents a gap between the amount of information stored in the brain and that available for prediction is established, where the latter will be referred to as predictive information as an analogy with Bialek's predictive information. This concept involves the FEP, the infomax principle, and the predictive information theory, and will be a useful measure to quantify the amount of information available for prediction.
Bifurcation Analysis of Hysteretic Systems with Saddle Dynamics
Authors: Esteban Marina , Ponce Enrique , Torres Francisco
Published: November 2017

This paper is devoted to the analysis of bidimensional piecewise linear systems with hysteresis coming from a reduction of symmetric 3D systems with slow-fast dynamics. We concentrate our attention on the saddle dynamics cases, determining the existence of periodic orbits as well as their stability, and possible bifurcations. Dealing with reachable saddles not in the central hysteresis band, we show the existence of subcritical/supercritical heteroclinic bifurcations as well as saddle-node bifurcations of periodic orbits.
Perjanjian Benefit Sharing Sebagai Upaya Perlindungan Dan Pemanfaatan Varietas Tanaman
Authors: Warsiki Susi Irianti Yuliana Diah Warsiki Susi Irianti Diah
Published: November 2017

Indonesia memiliki keanekaragaman kekayaan varietas tanaman lokal yang berlimpah, namun masyarakat Indonesia belum bisa menikmati manfaat ekonomi secara maksimal dari penggunaan sumber daya hayati terutama  varietas tanaman  lokal. Perjanjian Benefit Sharing memiliki makna kesepakatan bersama dalam  pembagian manfaat ekonomi sebagai kompensasi kepada masyarakat lokal atas tindakan komersialisasi varietas tanaman lokal oleh pihak lain.Benefit sharing diharapkan dapat meningkatkan kesejahteraan masyarakat lokal di Indonesia. Dan masyarakat lokal diberi hak untuk mengelola, memanfaatkan dan melestarikan varietas tanaman lokal yang ada.Kata Kunci : Perjanjian, Benefit Sharing, Perlindungan Hukum dan Varietas Tanaman Lokal
Urgensi Akta Notaris Dalam Perikatan Kerja Antara Kantor Jasa Penilai Publik dengan Perusahaan Emiten Terhadap Implikasi Penilaiannya di Bursa Saham
Authors: Ardiman Lazuardi
Published: November 2017

Jurnal ini bertujuan untuk mengkaji apakah Akta Notaris memiliki urgensi yang utama dalam perikatan kerja antara Kantor Jasa Penilai Publik dengan Perusahaan Emiten, terutama yang dapat berimplikasi terhadap bursa saham. Jenis penelitian ini adalah hukum normatif (Normative Legal Research) berdasar Pasal 1233 Kitab Undang-Undang Hukum Perdata tentang perikatan, Pasal 1870 Kitab Undang-Undang Hukum Perdata tentang Akta Autentik, Undang-Undang Nomor 8 Tahun 1995 Tentang Pasar Modal, Undang-Undang Nomor 21 Tahun 2011 Tentang Otoritas Jasa Keuangan dan Undang-Undang Nomor 2 Tahun 2014 Tentang Perubahan Atas Undang-Undang Nomor 30 Tahun 2004 Tentang Jabatan Notaris, serta dibantu dengan bahan-bahan hukum lain yang diuraikan, dideskripsikan dan dianalis keterkaitan satu sama lain. Dari hasil penelitian ini, terjawab bahwa Akta Notaris merupakan Akta yang penting untuk di buat dalam perikatan kerja antara Kantor Jasa Penilai Publik dengan Perusahaan Emiten, karena kedua belah pihak memiliki tanggung jawab hukum terhadap masyarakat luas (public) khususnya yang menjadi investor di bursa saham, terhadap transparansi, kompetensi, dan prospek bisnis yang baik. Alasan lain adalah karena dari peraturan-peraturan yang ada tidak ada yang secara eksplisit menentukan bentuk hubungan kerja antara para pihak.   Kata kunci: Akta Notaris, Perikatan, Kepastian Hukum.
Alcoholism: a view family / Alcoholismo: una visión familiar
Authors: Lloret Irles Daniel
Published: November 2017

Los efectos del consumo excesivo de alcohol sobre el organismo, son ampliamente conocidos, y son, posiblemente, el motivo desencadenante de que las personas con un problema de adicción a este tóxico comiencen un tratamiento de desintoxicación y deshabituación, aunque el problema real de esta adicción, como en muchas otras, sea probablemente las consecuencias familiares, sociales y laborales, que en la mayor parte de las ocasiones resultan devastadoras En este sentido, la familia, como contexto socializador primario del individuo, es el elemento central, más importante tanto a nivel de intervención, como preventivo, en relación al consumo de drogas. Está comprobado que el sistema familia desempeña un papel importante en el desencadenamiento de conductas de consumo, de abuso, y de adicción, (Jacob,T. Johnson, S. 1999) De manera que dejando a un lado los factores genéticos, se puede afirmar que los procesos de socialización familiar destacan su importancia al ser la base de predisponentes tales como las actitudes, la personalidad, el autoconcepto, los valores, y en última instancia las habilidades de comunicación. La relación entre familia y consumo de alcohol no se limita a la causalidad ya establecida, hay otra vertiente no menos importante, que se refiere a la trascendencia de esta patología en las interacciones familiares, y a las dinámicas de relación disfuncionales que se crean debido a este problema. AbstractThe effects that the abusive consumption of alcohol cause within the human organism are well known and are probably good reasons to begin a detoxification treatment for people who suffer a serious addiction to this highly toxic drug, although the real problem about this sort of addiction, as in the case of many others, is probably the negative consequences that it may cause for the family, the social and work settings, which, in most cases, prove to be devastating. In this respect, the family, as the prime socializing element for the individual, is the most important influence at the levels of both intervention and prevention of drug abuse. It has been proven that the family’s attitude plays an important role in the promotion of drug consumption, abuse and addiction (Jacob,T. Johnson, S. 1999). Apart from the genetic factors, however, we can affirm that the family’s social processes highlight their importance because they are the base of the underlying factors in this problem, such as their attitudes, their personalities, their self-esteem, their personal values and finally, their communication skills. The relationship between the family and alcohol consumption is not limited to the already established elements. There is another important angle to the problem. It is the far-reaching effects of this pathologic condition on the way the family interacts and on the dynamics of the malfunctioning relationships that this problem causes.
Full number: Volume 1, Number 1 / Número completo: Volumen 1, Número 1
Authors: De junio de 2001. Número completo
Published: November 2017

Full number: Volume 1, Number 1 / Número completo: Volumen 1, Número 1.
Neuroanatomical substrate drug addiction: system paper limbic / Sustrato neuroanatómico de la adicción a drogas: papel del sistema límbico
Authors: Rodríguez de Fonseca Fernando , Del Arco Ignacio , Ferrer Belén , Navarro Miguel
Published: November 2017

La adicción a drogas es una enfermedad crónica, recidivante, que se caracteriza por la pérdida del control sobre el uso de una sustancia, que pasa a ocupar un lugar preferencial en la vida del individuo. Es una enfermedad en la que se alteran los mecanismos de control de la conducta, en especial, los que atañen al control motivacional y emocional. Este artículo pretende revisar el papel que juegan en la adicción las estructuras encefálicas que participan en la organización de las conductas motivadas, y que se agrupan bajo el nombre genérico de sistema límbico. Este sistema participa tanto en el procesamiento de los fenómenos agudos de recompensa que activan las drogas de abuso, como en las neuroadaptaciones asociadas a la administración crónica de dichas drogas y en los fenómenos de aprendizaje que conducen a la formación del hábito anómalo que caracteriza a los adictos.