bluuebunny/crossref_metadata_2025 huggingface dataset:
Peculiarities of the social structure of the electorate of left-wing parties in the EU countries
Authors: Zverev Evgeniy
Published: September 2024

The article is devoted to the analysis of the political situation in the European Union, focusing on changes in support for left-wing parties in the context of global challenges. Transformations in the electoral preferences of EU citizens caused by economic and political turmoil and international conflicts are considered. The main focus is on the growing popularity of radical left populist parties. The analysis shows that traditional left-wing parties are losing support due to insufficiently radical proposals, which leads to fragmentation of their electorate. Radicalization of political sentiment is seen as a serious challenge, as radical movements are less predictable and can create political instability in the region. In this regard, analysts are faced with the question of possible changes in the political landscape, which is especially important in the context of tense international relations and sanctions pressure on Russia. The author emphasizes the need to understand political changes and forecast their consequences in order to develop effective electoral forecasts. The article considers the main results of the 2024 European Parliament elections, their impact on electoral preferences and changes in the EU political landscape. The theoretical approaches and empirical studies of leading domestic and foreign scholars in the field of studying party systems are analyzed, which allows us to assess current and future trends in European politics. The work also touches upon the issues of uniting left-wing forces in opposition to right-wing parties, as well as possible scenarios for the development of the political situation in the European Parliament and its impact on international relations and interstate interaction.
In the labyrinth of ideological search: ways to construct a memory of an uncomfortable past (on example of events of the 1917 Revolution and the Civil War)
Authors: Goloseyeva Anna , Khokhlov Andrey
Published: September 2024

This article is devoted to the problem of constructing a collective memory of the "inconvenient past" by modern elites of Russia on the example of the events of the 1917 revolution and the subsequent civil war. The conflict aspects of commemoration (installation of monuments and memorial signs) in the process of constructing an official historical narrative are considered. Concidered changes in the official historical narrative regarding the "difficult past" in different periods of time.
The preservation of historical memory largely depends on the political objectives of the current government, which not only supports collective memory through various commemorative practices, but also constructs a modern historical narrative. This narrative does not imply the restoration of Soviet historiography; it combines a variety of interpretations of the events of the Revolution and the Civil War in the context of building the historical continuity of Russian statehood. Therefore, the images of some Soviet figures coexist with the figures of their opponents, forming ideas among the mass audience about patriotic service to the Russian state, regardless of ideological and political views.
The "lost memory" is not being restored; current generations of Russians have not accepted the political experience of supporters of democratic socialism, who rejected Bolshevism and did not support the "white movement" in the civil war. The attitude towards the losers in the fight against the Bolsheviks today is negative, as towards weak and incapable politicians. Considering historical memory as an integral part of collective memory, it is concluded that only those events of the past that are perceived by society as extremely useful for modern generations are integrated into the structure of collective consciousness. In addition, the inertia of public consciousness affects the "selection of event material". For this reason, during the entire post-Soviet period, it was not possible to completely replace the former Soviet ideological cliches with a new historical narrative.
The frontier factor in the formation of the hero's image in Russian society
Authors: Podlesnaia Mariia , Shevchenko Oleg
Published: September 2024

The article examines the concept of a hero in relation to the concept of a frontier, which the authors understand as a "contact field", a boundary that connects rather than separates the spatio-temporal field of conjugation of two or more realities. Particular attention is paid to the development of the frontier as a point of assembly and the personality of the hero and the new social normality. The need for a comparative analysis of the concepts of subject, actor, and hero that already exist in sociology is indicated. An attempt is made to differentiate these concepts, the main features of the hero as a total subject are given, the importance of distinguishing between an everyday hero and a "frontier" hero is indicated. The influence of the frontier as a factor in the formation of the hero's image is substantiated based on the materials of an empirical study conducted by the authors of the article in eight Federal Districts of the Russian Federation in 2023 (n = 1350). For this purpose, data are analyzed on a number of open and semi-closed questions depending on the place of residence of the respondents, that is, the territorial factor. The authors of the article come to the conclusion that the length of Russia and the diversity of its regions, the frontier status of some of them, provide the corresponding specificity and demand for a hero. Respondents from those subjects of the Russian Federation that currently act as a frontier themselves articulate their idea of a hero and heroism much more clearly. The military hero remains the textbook hero for Russians. A significant part of the independently named heroes are outstanding personalities, primarily of the Soviet era, mainly military leaders, politicians, child heroes of the Great Patriotic War. Everyday workers and laborers - doctors, health workers, volunteers, rescuers, teachers, scientists, etc., which was typical for the Soviet era, are not currently singled out as heroes by respondents. Which leads to the conclusion that the actor of Soviet modernism, which was associated with heroism, was closely associated with the concept of a hero (in particular, labor), is not relevant in the minds of Russians today. Such transformations are associated by the authors with the influence of the situational factor, as well as with the change of the corresponding social ontologies.
Migration policy as a factor influencing the USA presidential election
Authors: Gadzhimuradova Gyulnara , Sumin Kirill
Published: September 2024

The article presents the transformation of US migration policy and analyzes its impact on the balance of power in the 2024 presidential election campaign. The 2024 election campaign in the US is characterized by significant differences between the major parties and their voters, as well as an emphasis on key economic and immigration issues that have divided American society. Mexico is the main labor donor to the US, and it is also a gateway for illegal migration from Latin America and Southeast Asia. Almost all the time of the existence of the United States, the immigration policy of the country shows that migration plays an important role in the development of American society. The problem of illegal migration has always existed and continues to have a significant impact on the socio-economic development of the country. The current U.S. immigration strategy combines continuity with restrictive measures, while seeking to adapt migration flows to the economic needs of the country. The article analyzes the impact of migration policy on the U.S. political landscape during the 2024 election campaign. Migration policy in the United States today is a tool for conducting political struggle and "settling scores". Illegal migrants from Latin American countries will have a particular impact on the upcoming elections, so a characteristic feature of the 2024 election campaign is a cross-party struggle for the Latin American electorate, coupled with tougher migration policies. The authors draw attention to the reasons for the transformation of the US migration system and give their forecast regarding the outcome of elections in the country under certain conditions.
Strengthening Moral Education Values: Sociological Analysis of the Mbah Sholeh Haolan at Pesantren Benda Kerep, Cirebon
Authors: Rusmana Dadan , Rosyidin Didin Nurul , Saefullah Asep , Burhanuddin Dede , Bin Zainuddin Ghazali
Published: September 2024

This article explores the role of Mbah Sholeh haolan (commemoration) in strengthening Islamic education in Benda Kerep Village. This event serves as a cornerstone for cultural preservation, intergenerational learning, and practical implementation of Islamic values. The kyai, or spiritual leaders, play a pivotal role in guiding the community, reinforcing their authority and the respect they command. The haolan facilitates social cohesion, fosters a strong sense of identity, and exemplifies the community’s commitment to Islamic teachings. By examining the significance of Mbah Sholeh haolan, the article provides insights into how traditional Islamic communities can navigate the challenges of modernity while preserving their religious and cultural heritage. This study show that commemoration is one of the means used to pass on the cultural and religious values contained in "Wasiat Sepuh" as one of the character education and character-building. Kyai is the central figure, the foremost patron, followed by the community, so what Scott calls a patron-client cluster is formed. Kyai in Benda Kerep serves as an information leader who, in many ways, trumps the role of formal government officials. Kyai serves as the community's protector, a place to seek advice, and the final decision-maker on various problems in the area.
Fabry nephropathy: focus on podocyte damage and therapeutic target
Authors: Zhang Dan , Xie Kenan , Zhang Jiong
Published: September 2024

Fabry disease, a rare X-linked lysosomal storage disorder, is marked by a deficiency in the activity of the enzyme α-galactosidase A. This deficiency results in the accumulation of globotriaosylceramide (Gb3) within various tissues and organs, which leads to life-threatening complications and poor prognosis. Clinical manifestations are multisystemic, heterogeneous, and progressive. Early diagnosis and treatment are of great importance. Fabry nephropathy lesions are characterized by a cell vacuolization of glomeruli, tubules, interstitium, and arteries and by ultrastructural myelin bodies. Kidney injury can occur in various structures, with the podocytes being the first to be impacted due to their low regeneration and extensive exposure to Gb3. The accumulation of Gb3 causes injury to podocytes, which are essential components of glomerular cells, responsible for maintaining the integrity of the glomerular filtration barrier. Enzyme replacement therapy, dynamic monitoring of podocyte injury, and research on the repair and regeneration mechanism of podocyte injury will contribute to the overall treatment of kidney damage in Fabry disease and improve the renal prognosis.
Separation of multicomponent gas mixtures
Authors: Stepaniuk Andrii , Kornienko Yaroslav , Dmytruk Andrii
Published: September 2024

In the production of granular organo-mineral fertilizers using the fluidization technique by dehydrating heterogeneous liquids, as an energy-efficient technology, there is a need to purify the spent coolant containing solid particles, dust and a significant amount of water vapor. Solid particles up to 20 microns in size are effectively captured in cyclone devices. To further capture water vapor and fine solid particles, a scrubber is used with an additional circulation circuit involving an additional bone of water, which, upon reaching a concentration of more than 20%, is discharged back to the granulation stage. This leads to an increase in energy consumption for production in general.   Condensation of vapors in a dispersion containing 5-7% (w/w) moisture in the form of water vapor at the second stage of purification will increase the level of environmental safety in production. To select an innovative method of separation of multicomponent gas dispersions accompanied by a change in the aggregate state and a rational design of the apparatus, a review of scientific articles and developments such as systematization of existing methods was carried out.
Such an approach makes it possible to choose the optimal solution for the separation of gas-dust and gas-liquid flows in the conditions of the existence of a large number of types of equipment design and the level of their innovation. In addition to the rational design of the devices, great attention was also paid to the issues of energy efficiency, resource saving and ensuring the state of environmental safety at production facilities in the conducted research.
Based on the results of the analysis, it is proposed to use a scheme of consecutively installed cyclones CN-11 and SK‑CN-33. It is proposed to use the ЦН-11 cyclone for the preliminary capture of highly dispersed dust, and the SK-CN‑33 for condensation and capture of water vapor and solids not caught in the previous cyclone particles.
Designing a model predictive controller for graphite baking process
Authors: Putiatin Redrikh , Zhuchenko Anatoliy
Published: September 2024

Model predictive controller provides better control quality for graphite products baking process than PID and its variations. The drawback of MPC is its high sensitivity to object modelling errors. If all of object parameters are varied just by 3 % simultaneously then MPC provides satisfactory control no more.
In the current paper we design an adaptive MPC for baking process control. In order to identify furnace section “under the fire” on-line, we utilize recursive least squares algorithm with forgetting factor equal to 0,98. We compare conventional and adaptive MPCs in the following cases: accurate model; undesirable deviations of object parameters from model parameters (object is time invariant); desirable deviations; time variant object with step-changing parameters. In each case adaptive MPC provides control that ensures temperature difference inside the hottest (the most “dangerous”) graphite bar to be small enough, and even gives some margin for it (0,8 % to 8 %). However, the cost for this is increased process duration (4,8 % to 142,1 %) and more fuel-consuming (1,2 % to 106,2 %) than in case of non-adaptive MPC, even if the latter provides satisfactory control as well.
In general, it is reasonable to use an adaptive MPC instead of a conventional one. Margin of economical reasonability needs further research. Also, it is necessary to compare different identification methods in order to achieve faster transition process.
Polymer gel materials based on polyvinyl alcohol and silver nanoparticles
Authors: Demchenko Valerii , Zahorodnia Svitlana , Rybalchenko Nataliia , Artiukh Liubov , Zaremba Polina , Yurzhenko Maksym , Sytnyk Illia , Ovsyankina Viktoriya , Neimash Volodymyr
Published: September 2024

Recently, issues of technogenic and environmental safety have come to the fore in the development of civilization. Currently, there is a tendency to increase the number of man-made emergencies. One of the ways to mitigate their impact and consequences on the population is the creation of innovative medical materials.
Therefore, the idea of ​​developing a non-toxic, antibacterial and antiviral polymer hydrogel with given functional properties as a wound dressing is relevant today.
 The work is devoted to the creation of silver-containing gel materials based on polyvinyl alcohol and polyethylene glycol. Hydrogel nanocomposite materials were obtained by reduction of silver ions with the help of ascorbic acid followed by cross-linking of polymer macromolecules by irradiation with a high-energy electron beam. The structure of hydrogel materials was studied by the method of wide-angle X-ray scattering and the presence of metallic silver in the studied polymer systems was confirmed. It was established that polymeric hydrogel materials PVA-PEG-1%-Ag exhibit antimicrobial and antiviral activity. It was found that the investigated polymer hydrogel materials with silver nanoparticles do not exhibit a toxic effect.
valuation of Ethanol Grade on the Robustness of Acid Number Determination in Fish Oil
Authors:   Universitas Islam Indonesia, Purbaningtias ri Esti , Sandy Sandy
Published: September 2024

The robustness evaluation of the acid number analysis method in fish oil was carried out to see the effect of the type of ethanol used as a solvent in the titration process. The types of ethanol used in this study were pro analysis grade, pharma and food grade, and technical grade. The acid number values (mgKOH/g) in fish oil with various solvents obtained were 2.3955±0.3211 for pro analysis grade; 2.7932±0.2983 for pharma and food grade; 2.7812±0.3362 for technical grade 1; 2.7031±0.3405 for technical grade 2. The acid number for all types of ethanol has a value that is in accordance with the requirements of SNI 8467: 2018 where the acid number value must be less than 3 mgKOH/g. However, if the measurement uncertainty value is included in the calculation, only the pro analysis grade ethanol solvent has an acid number value that is in accordance with the requirements of SNI. The results of the ANOVA test also showed that there was a significant difference in the variation of ethanol types for determining acid numbers because the calculated F value (13.9004) was greater than the F table (3.0984). Therefore, the solvent that must be used in the method of determining acid numbers in fish oil is pro analysis grade ethanol.
Spectrophotometric Determination of Norepinephrine in Industrial Equipment Cleaning Rinse Water by Its Own Absorbance and The Tollens’ Reagent
Authors:   Chemical Analysis Laboratory, Quality Assurance Department, LLC “Velpharm”, Prospekt Konstitutsii 11, 640008 Kurgan, Russian Federation, Nikolaychuk Pavel Anatolyevich
Published: September 2024

A literature review of the available spectrophotometric methods of determination of catecholamines is presented. Based on this review, two simple spectrophotometric methods for the determination of norepinephrine bitartrate in pharmaceutical formulations and industrial equipment cleaning rinse waters were chosen and validated. The first method for the determination of norepinephrine at ppm levels utilizes the absorbance band of the solution of norepinephrine bitartrate at 279 nm. The second method for the determination of norepinephrine at ppb levels is based on the reaction of norepinephrine with the Tollens’ reagent in the presence of the cationic surfactant cetylpyridinium chloride and the colorimetric determination of the formed colloidal silver nanoparticles. The calibration graphs are linear in the range from 1 to 150 mg/l of norepinephrine for the first method and 25 µg/l to 10 mg/l for the second method. The molar attenuation coefficients are 388 and 7560 m2/mol, respectively, the limits of detection are 1.1 mg/l and 3.1 µg/l, and the limits of quantification are 3.3 mg/l and 9.4 µg/l, respectively. Both methods are selective concerning the common excipients, show good accuracy (the relative uncertainties do not exceed 4 and 7%, respectively) and precision (the relative standard deviations do not exceed 4 and 7%, respectively), and do not require lengthy sample preparation and sophisticated laboratory equipment.
Advancements in NMR and IR Spectroscopy: Enhancing Metabolomics and Disease Diagnostics in the Health Sector: A Comprehensive Review
Authors:   Universitas Palangka Raya ,, Saputra Rizki Rachmad , Ariefin Mokhamat , Kumalasari Meiyanti Ratna , Dongoran unita , Tampubolon Mulani Jeni Lestari , Sulistiawati Putri , Simangunsong Sri Yulandari , Ariska Risya , P Pandu Gizta Rapi , Siska Amelia , Yanti Jeddah , Maknun Luluil
Published: September 2024

Metabolomics has emerged as a critical field in understanding biological processes and disease mechanisms, necessitating advancements in analytical techniques to handle complex biological samples. This review explores the global landscape of metabolomics, with a focus on the use of spectroscopy and spectrometry. Techniques such as UV-Vis and Fourier Transform InfraRed (FTIR) spectroscopy offer fast and cost-effective metabolite tracing but are limited by their sensitivity, particularly for low-abundance metabolites. Nuclear Magnetic Resonance (NMR) spectroscopy, despite being less sensitive than mass spectrometry (MS), provides unparalleled structural information, distinguishing metabolites with similar mass-to-charge ratios. NMR's capability to detect metabolites in the 1-10 µM range highlights its effectiveness in metabolomics. This review categorizes advancements in these techniques, starting with global contributions to spectroscopy, followed by detailed discussions on FTIR strategies for metabolite tracing, and concluding with NMR's qualitative and quantitative applications in metabolomics and disease diagnostics. The review underscores the continuous development in sample preparation and data integration, enhancing the accuracy and applicability of these techniques, positioning NMR and FTIR as essential tools in modern metabolomic research.
Assessment of Water Supply and Water Quality in the Rural Area of Obokun Local Government, Osun State, Nigeria
Authors: Adedotun Samuel Babatunde , Adedotun David Oluwatoyin , Ogundahuns Dele Sunday , Ibrahim Rafiu Babatunde , Olayode Olayiwola , Ewedairo Samuel Kola
Published: September 2024

Rural areas are not only faced with the problems of rural depopulation but also with the problem of water supply and water quality which is a basic necessity of life. In light of this, this paper assesses the rural water supply situation and the bacteriological quality of different water sources in the Obokun Local Government Area of Osun State, Nigeria. The safety of the water sources for human consumption and possible occurrence of the water borne diseases in the study area were determined. The study employed descriptive and analytical methods of data analysis to achieve the objectives of the inquiry. Findings showed that the study area suffered from inadequate water supply and poor locations of the sources of water: The study also revealed that the microbiological quality of the water sources used was unsafe, poor and not acceptable for human consumption. In addition, many man- days-hours were wasted in search of water. It is therefore recommended that the government should make the rural water supply and the maintenance of water quality a priority in its policy formulation.
Genome-wide Identification and Characterization of the Terpenoid Synthase Gene Family in Physcomitrella patens
Authors: Ma Wei , Wan Xiukun , Yao Ge , Han Penggang , Jiang Hui
Published: September 2024

Terpenoids are crucial secondary metabolites found in plants, essential for numerous physiological functions such as defense strategies, signal communication, and adaptation to environmental stresses. The enzymes referred to as Terpene Synthases (TPS) play crucial roles in the production of these compounds, fulfilling an essential role throughout the entire biosynthetic pathway.Despite their importance, systematic studies on the TPS genome in Physcomitrium patens (P. patens) remain inadequate. This research offers an extensive bioinformatics evaluation of the TPS genes in P. patens, aiming to clarify their possible functions in plant development, growth, and responses to stress. Preliminary examinations were conducted on the physicochemical characteristics, secondary protein structures, subcellular distribution, and genetic configurations of the TPS genes in P. patens. Initial analyses were performed on the physicochemical properties, protein secondary structures, subcellular localization, and gene structures of the TPS genes in P. patens. The findings demonstrate that TPS family members are dispersed across six chromosomes, with ten TPS family members identified. Analysis of conserved motifs revealed that the PpTPS members exhibit high sequence conservation, suggesting that these enzymes maintain stable structural characteristics during terpene synthesis. Further examination of evolutionary pressures indicated that TPS family members are predominantly subjected to purifying selection, which helps preserve the structural stability of TPS enzymes. Furthermore, an analysis of cis-acting elements indicated that TPS genes might respond to various factors, including light, plant hormones, tissue development, and environmental stressors. This suggests that TPS genes could be vital in managing how plants adapt to changes in their environment. Tissue expression profiling revealed that TPS family members have significant functions across various developmental stages and tissues. This is demonstrated by qRT-PCR analyses, indicating that the expression of the PpTPS gene is influenced by abscisic acid (ABA), methyl jasmonate (MeJA), sodium chloride (NaCl), and polyethylene glycol (PEG). The findings suggest that the PpTPS genes could play an essential role in the functional development of plant leaves and in their responses to abiotic stress.In summary, this research presents a comprehensive examination of the TPS family members in P. patens, yielding important perspectives on the functions of the PpTPS7 and PpTPS8 genes in the development of leaves and responses to abiotic stress.The findings contribute to a deeper understanding of the functions and regulatory mechanisms of TPS genes and present new perspectives and strategies for the enhancement and application of P. patens.
Mitochondrial Reactive Oxygen Species Dysregulation in Heart Failure with Preserved Ejection Fraction: A Fraction of the Whole
Authors: Martinez Caroline Silveira , Zheng Ancheng , Xiao Qingzhong
Published: September 2024

Heart failure with preserved ejection fraction (HFpEF) is a multifariousness syndrome, account-ing for over half of heart failure (HF) patients receiving clinical treatment. The prevalence of HFpEF is rapidly increasing in the coming decades as the global population ages. It is becoming clearer that HFpEF has a lot of different causes, which makes it challenging to find effective treatments. Currently, there are no proven treatments for people with deteriorating HF, or HFpEF. Although the pathophysiologic foundations of HFpEF are complex, excessive reactive oxygen species (ROS) generation and increased oxidative stress caused by mitochondrial dys-function seem to play a critical role in the pathogenesis of HFpEF. Emerging evidence from an-imal models and human myocardial tissues from failed hearts shows that mitochondrial aberra-tions cause a marked increase in mitochondrial ROS (mtROS) production and oxidative stress. Furthermore, studies have reported that common HF medications like beta blockers, angioten-sin receptor blockers, angiotensin-converting enzyme inhibitors, and mineralocorticoid receptor antagonists indirectly reduce the production of mtROS. Despite the harmful effects of ROS on cardiac remodelling, maintaining mitochondrial homeostasis and cardiac functions requires small amounts of ROS. In this review, we will provide an overview and discussion of recent findings on mtROS production, its threshold for imbalance, and the subsequent dysfunction that leads to related cardiac and systemic phenotypes in the context of HFpEF. We will also focus on newly discovered cellular and molecular mechanisms underlying ROS dysregulation, current therapeutic options, and future perspectives for treating HFpEF by targeting mtROS and associ-ated signal molecules.
Main Microclimatic Indicators in a Milking Parlor for Dairy Cows
Authors: Dimov Dimo , Penev Toncho , Marinov Ivaylo Bogdanov
Published: September 2024

The study was conducted in the milking parlor of a cattle farm with a capacity of 400 cows of the Holstein-Friesian breed. The milking installation was a double 8 "Herringbone" type without windows, and the roof was constructed of glass. The reporting of temperature, air humidity and temperature-humidity index (THI) was performed three times during each milking (at the start, in the middle and at the end of milking) with measurements repeated during the morning, noon and evening milking. The highest mean and maximum daytime air temperature values were recorded in summer and spring. Although the average values for the spring season were lower than those for summer (by about 4 ⁰ C), the maximum values reached were equally high – 31.4 ⁰ C. In terms of relative air humidity, the highest mean values were reported for the winter sea-son – 82.39%. For the other seasons, the relative humidity values were on average high and close in value - from 62.51 to 67.46%. In THI, the highest average daily and maximum values were re-ported in the summer months - 73.41 and 80, respectively.
Circular RNA Vaccines: Pioneering the Next-Gen Cancer Immunotherapy
Authors: Das Uddalak , Banerjee Soupayan , Sarkar Meghna , Muhammad Fathah , Kaur Soni Tanveen , Saha Madhumita , Pradhan Gayatri , Chatterjee Bhaskarjyaa
Published: September 2024

Circular RNA (circRNA) vaccines are emerging as a revolutionary strategy in cancer immunotherapy, offering novel mechanisms for inducing robust and durable immune responses. Unlike traditional linear mRNA vaccines, circRNAs exhibit exceptional stability, enhanced translational efficiency, and resistance to exonuclease degradation, making them ideal candidates for vaccine development. This review delves into the fundamental principles underlying circRNA biology, highlighting their unique structural advantages and translational potential. We examine recent advancements in circRNA vaccine design, focusing on their application in oncology. As the circRNA-based cancer vaccine is a relatively novel approach, accounts of all the major studies describing the efficacy have been discussed. To maximize the anti-cancer effects of circRNA vaccines, we also investigate their combination with other immunotherapeutic modalities such as immune checkpoint inhibitors and adoptive cell therapies. Large-scale manufacturing, immunogenicity optimization, delivery systems, and other challenges and future directions in the sector are also discussed. This study aims to thoroughly analyse the state-of-the-art and potential future applications of circRNA vaccines in cancer immunotherapy, highlighting them as exciting possibilities for next-generation cancer therapies.
An Empirical Study on ERP Travel, Trade, and Tourism Systems
Authors: Pervez Huma , Mohsin Muhammad , Ali Abid
Published: September 2024

In this paper, we present findings from a recently completed research about the use of enterprise resource planning (ERP) in travel, trade, and tourism businesses. Initially, we selected twelve existing travel, trade, and tourism ERP systems and preform practical analysis and testing of these systems via JMETER and Google chrome Lighthouse tools. In addition to that, an online survey was conducted (with an e-mail invitation and telephone call reminder) to collect data from three Pakistani Travel, Trade, and Tourism organizations. Furthermore, we adopted qualitative research practices by going through various research papers and research studies from journals, books, and internet, etc. This study is constructed on only secondary statistics. The goal of this article is to look at ERP systems in terms of their concept and use, as well as how they affect the modern travel business. An ERP system is a business system that integrates several corporate processes into a single database, such as supply chain management, manufacturing, financial management, and project management. ERP systems are utilized in a variety of businesses around the world, including in the manufacturing and service industries. Across a range of industries, service firms have recently spent significant resources on the implementation of Enterprise Resource Planning (ERP) systems to improve the efficiency, cost-effectiveness, and quality of service operations. To assist them to build their businesses, the travel, trade, and tourist industries all rely on an integrated information network. The work focuses on only one industry i-e Travel, Trade, and Tourism. This may limit the applicability of its broad conclusions to other industries or industries. The findings of this study compare and contrast the ERP implementation challenges faced by existing organizations of travel, trade, and tourism companies. This is the first empirical study on the difficulties surrounding ERP installation in travel, trade, and tourism companies. It is also the first study to compare ERP adoption in multiple companies in the areas of travel, trade, and tourism.
Proof of Goldbach's Conjecture
Authors: Hou Shaosheng , Huang Yue , Ma Lin-Jun
Published: September 2024

The paper presents two novel mathematical approaches to prove Goldbach's conjecture. The conjecture states that every even number greater than or equal to 6 can be expressed as the sum of two odd prime numbers. We propose that the conjecture has only four genetic codes, and as long as one of them remains valid, the conjecture continues to hold. Through these new mathematical ideas, we aim to prove the validity of Goldbach's conjecture comprehensively.
Reviewing Digestate Thermal Valorization: Focusing on the Energy Demand and the Treatment of Process Water
Authors: ABDELFATAH-ALDAYYAT EBTIHAL , González-Rojo Silvia , Gómez Xiomar
Published: September 2024

Anaerobic digestion is a feasible solution for the treatment of organic wastes. The process can reduce the amount of biowaste by stabilizing the organic material and producing biogas susceptible to energetic valorization. However, the digestate needs further valorization when land application is considered unfeasible. Thermal treatments, such as gasification, pyrolysis, and hydrothermal carbonization, are alternatives capable of transforming this material into valuable syngas, obtaining, in many cases, a carbonized stream known as biochar. The feasibility of the process depends on the energy demand for the drying stage and the treatments available for removing contaminants from the syngas, attaining high-quality products, and treating the process-derived water. In the present manuscript, these critical aspects were reviewed considering the characteristics of digestates based on their origin, the modifications of this material during anaerobic digestion, and the way digestate structure affects the final thermal valorization outcome. Emphasis was placed on the energy demand of the global approach and by-product treatments.
Comparison of Croup Management Patterns between Pediatricians and Emergency Medicine Physicians: A Single Pediatric Emergency Department Study
Authors: Song Ho-Young , Kwon Jae-Hyun , Park Soo Hyun , Kim Min-Jung , Byun Young-Hoon , Paek So-Hyun
Published: September 2024

Background/Objectives: This study aimed to compare croup management patterns between pediatricians and emergency medicine (EM) physicians to enhance pediatric emergency care and inform the training of future specialists. Methods: A retrospective review of medical records was conducted for 1,676 children diagnosed with croup who visited a single pediatric emergency department (PED) from March 2019 to February 2023. Patient characteristics, management patterns, and the impact of physician specialty on emergency care were analyzed. Results: EM physicians used injected dexamethasone monotherapy more frequently, whereas pediatricians favored combined use of nebulized epinephrine and dexamethasone. Pediatricians also prescribed oral antibiotics and corticosteroids at discharge more often. The appropriate use of nebulized epinephrine based on the Westley Croup Score was significantly higher in the EM physician group. Despite these differences, there were no significant disparities in PED length of stay or revisit rates within 48 hours. Conclusions: EM physicians adhered more closely to clinical guidelines for croup management. These findings underscore the need for standardized, evidence-based pediatric emergency care and provide valuable insights for training programs in this field.
Cellulose-Based Acoustic Absorber with Macro-Controlled Properties
Authors: Lefebvre Jérôme , Genestie Benoit , Leblanc Alexandre
Published: September 2024

Cellulose-based materials are now commonly used, including in the field of acoustic comfort. Often presented as a less environmentally impactful alternative to traditional acoustic absorbents (such as melamine, glass wool, etc.), these cellulose-based materials are more frequently derived from recycling, thus undergoing in most cases the technical process allowing these cellulose fibers to be obtained, thus inheriting the acoustic properties of the latter, with limited or even non-existent control. This paper proposes a manufacturing process that allows for the production of cellulose foam with precise control over its porosity, pore size, and interconnections. In addition to exhibiting remarkable sound absorption properties, this process also enables the fabrication of gradient porous structures and other hybrid materials that can result in remarkable sound absorption properties.
Knowledge and Prevalence of Latent Tuberculosis Infection: A Pilot Study in Patients Attending a Primary Healthcare Clinic in Rural Eastern Cape, South Africa.
Authors: Magwaza Cebo , Laguda-Akingba Oluwakemi , Apalata Teke , Faye Lindiwe Modest
Published: September 2024

Latent tuberculosis infection (LTBI) remains a significant global health concern, particularly in regions with high tuberculosis (TB) prevalence, such as South Africa. This pilot study aimed to evaluate the prevalence of LTBI and assess patient knowledge about the condition in a primary healthcare clinic in rural Eastern Cape, South Africa. A cross-sectional design was used, and convenience sampling recruited outpatients aged 18 years and older with no prior history of TB. Blood samples were analyzed using the QuantiFERON-TB Gold assay to determine LTBI status, and a survey assessed patient knowledge of LTBI. Strong positive correlations were observed between what patients understand by the term LTBI and how is LTBI different from TB (0.70), patients understand by the term LTBI and the risk factors for developing LTBI (0.70), how is LTBI different from TB and the risk factors for developing LTBI (0.78), and how is LTBI different from TB and the recommended treatments for LTBI (0.79), indicating overlap in understanding. In contrast, negative correlations between if patients ever heard of latent LTBI before and patients understanding the term LTBI (-0.25), the risk factors for developing LTBI (-0.22), LTBI progressing to active TB (-0.27), and the recommended treatments for LTBI (-0.27). This divergence points to different dimensions of patient knowledge and awareness. Age, gender, occupation, comorbidities, and HIV status showed varying LTBI positivity trends. Among younger patients aged 20-29, 15.4% tested positive, while the 30-39 group showed a nearly equal split between positive (48.1%) and negative cases. A higher positivity rate was seen in females (39.1%) compared to males (31.6%). Unemployed individuals had higher positivity rates, suggesting socioeconomic factors' influence. Comorbidities, especially hypertension, diabetes, and asthma, correlated with higher LTBI positivity among females, but this was less evident in males. HIV-positive patients had a higher LTBI-negative rate compared to HIV-negative patients. These findings suggest that demographic and health factors, including age, gender, occupation, comorbidities, and HIV status, may predict LTBI positivity.
Enhancing Production Efficiency of Irrigation Projects: The Impact of Stakeholder Participation
Authors: Singh Saran S.
Published: September 2024

This study investigates the impact of stakeholder participation on the efficiency of irrigation projects by the implementation of Farmers Water User Committees (FWUCs). Utilising a difference-in-difference methodology, the research analyses data from 79 irrigation projects over a 13-year period. The findings reveal a statistically significant positive correlation between FWUC establishment and improved project effectiveness, even when controlling for variables such as project size, age, and socio-economic factors. Smaller, newer projects exhibited higher effectiveness, whilst remote locations faced greater challenges. The temporal analysis indicates that the benefits of participation accrue gradually, underscoring the importance of sustained implementation. These results carry significant implications for public enterprise reform, particularly in irrigation management. The study contributes to the growing body of evidence supporting the efficacy of stakeholder participation in public enterprise management, offering valuable insights for policymakers seeking to enhance the efficiency and sustainability of irrigation systems.
Validity and Reliability of the Self-Administered Timed Up and Go Test for Monitoring the Risk of Falls in Community-Dwelling Older Adults
Authors: Reis Magda , Teixeira Maria , Carvão Carlota , Martins Anabela
Published: September 2024

Objectives: The aim of this study was to determinate the validity and the reliability of the self-administered Timed Up and Go (TUG) test, a gold standard test for fall risk screening, when compared to the traditional face-to-face assessment carried out by a physiotherapist. Methods: A total of 37 community-dwelling adults, mean age 61.78±6.88, 73% female, who took part in fall risk screening actions in the central region of Portugal, were assessed. The protocol included sociodemographic and history of falls questions, the Self-Efficacy for Exercise questionnaire, the Activities and Participation Profile Related to Mobility (PAPM) and three functional tests, namely the 10-Meter Walking Speed (10-MWS), TUG and 30 Seconds Sit to Stand (30s STS) tests. Within an interval of 18-24 hours after the face-to-face moment, the participants were instructed to self-administer the TUG test at home. The validity and reliability of self-administered TUG test were examined using the limits of agreement, clinically acceptable limit, intra-class correlation coefficients (ICC), paired t-tests and Pearson´s coefficient correlation (r). Results: The limits of agreement for self-administered assessment were within the clinically acceptable limits. The average result of the face-to-face TUG test and self-administered TUG test was 7.47 ± 2.45 and 7.57 ± 3.10 seconds, respectively. When comparing the two evaluations, they were strongly associated (r=0.716, p<0.001), with an excellent ICC of 0.82 (0.65-0.91), for a 95% confidence interval. Conclusion: The use of the self-administered TUG test for the screening of risk of fall, using low-cost technology, appears to be valid and reliable in community-dwelling adults aged 50 and over.
Generational Differences in Visual Engagement: Applying the Visual Interaction Analysis (VIA) Methodology Composed of Eye Tracking and Virtual Reality
Authors: Guerra-Tamez Cristobal Rodolfo , Rodríguez-Sánchez Pedro Daniel
Published: September 2024

Understanding visual engagement in marketing is crucial for optimizing user experience and enhancing campaign effectiveness. This study introduces the Visual Interaction Analysis (VIA) methodology, utilizing advanced eye-tracking technology within immersive virtual reality (VR) environments to examine generational and gender differences in visual engagement after exposure to advertising materials. Using the Cognitive 3D platform for precise data capture, this research analyzed fixation patterns—total fixations, duration of fixations, and average duration per fixation—across Millennial and Generation Z cohorts. The analysis involved 44 participants, who were exposed to three posters in controlled VR settings. Results revealed significant generational differences: Generation Z demonstrated more focused attention, with higher fixation counts and longer total fixation durations compared to Millennials, suggesting that differences in media consumption and technological adaptation influence engagement strategies. However, both generations showed a similar depth of engagement, as indicated by the average duration per fixation. Gender analysis within Generation Z further revealed that female participants engaged for longer periods per fixation, indicating deeper processing of visual information. This methodology offers a robust framework for quantifying visual engagement, providing actionable insights that can help marketers tailor strategies and optimize campaign designs before launch.
Dmany Nexus Protocol: A Decentralized Reputation Protocol for Scalable Web3 Economies Through Dynamic Trust Quantification and Zero-Knowledge Mechanisms
Authors: Stolberg Stanislav
Published: September 2024

The advent of Web3 technologies promises a paradigm shift toward decentralized and autonomous economic interactions enabled by blockchain and smart contracts. However, the lack of robust trust and reputation mechanisms hinders its evolution into a fully functional economic system. This paper introduces the Dmany Nexus Protocol, a decentralized reputation system that quantifies user trustworthiness through verified on-chain and off-chain actions. By integrating principles from information economics, game theory, and mechanism design, the protocol addresses issues of information asymmetry, moral hazard, and adverse selection inherent in decentralized networks. Leveraging the Dmany Quest Engine for decentralized task management and employing zero-knowledge proofs for privacy preservation, Dmany Nexus establishes a foundation for trust and cooperation in the Web3 ecosystem. The protocol enhances economic efficiency, mitigates security risks like Sybil attacks, and fosters mass adoption by enabling secure, privacy-preserving interactions among pseudonymous actors.
The Role of Artificial Intelligence in Military Systems: Impacts on National Security and Citizen Perception
Authors: Uddin Hasan Mir Moin , Islam Md Suzon
Published: September 2024

This study examines the rationale and perceptions surrounding AI in military technologies, focusing on its application in autonomous weapons systems (AWS), intelligence, surveillance, and reconnaissance (ISR), and decision-support systems (DSS). AI models, such as unmanned aerial and ground platforms, showed high mission success rates, with 92% mission accomplishment, 95% true positive threat identification, and low false alarms. AI's effectiveness surpassed human operators, particularly in response time and threat detection. A global survey revealed mixed opinions: two-thirds believed AI enhances national security, yet 70% opposed autonomous weapons due to ethical concerns, particularly civilian casualties. The study highlights AI's advantages in improving decision-making speed and accuracy but acknowledges challenges such as ethical considerations and public trust in autonomous systems. Future research should address ethical AI models, international humanitarian law (IHL) standards in military operations, human-AI interaction in hazardous environments, and policies related to military robotics and accountability. Understanding and enhancing public awareness of AI in military contexts is also essential.