bluuebunny/crossref_metadata_2025 huggingface dataset:
The challenges and opportunities of commercialisation
Authors: Howard Sophie
Published: December 2023

​Government is challenging New Zealand public research organisations to increase the rate of commercialisation of intellectual property (IP) and research findings. It is generally accepted that a high-tech economy offers the potential to increase GDP through exports of high-value products, and this view is well supported within universities. However, in practice, academic staff face conflicting incentives and pressures to invest their time and succeed in the university environment. Commercialisation managers work at the interface of the university culture and the external business world, and manage the conflicting philosophies and drivers of each side. Unlike ‘translators,’ these individuals add value by creating opportunities and proactively managing the supply and demand of early-stage, high-risk ideas. Viclink, the commercialisation arm of Victoria University of Wellington, has been in turnaround mode for the past 24 months in an aim to deliver increased value from its research and IP, and has seen first-hand the challenges of working in the market for innovation. New Zealand universities have approached and scoped their roles quite differently. Around the world different models and priorities exist for commercialisation and tech transfer of university IP. A recent case study on a clean tech start-up company highlights several of the observations and opportunities in commercialising publicly funded research, and on the relationships between inventors, commercialisation companies, incubators and investors. This discussion provides a summary of current challenges and opportunities in commercialisation, as observed by practitioners in a university setting.
Drawing it together
Authors: Bain Murray , James Colin
Published: December 2023

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ANALISIS BENTUK PRODUK KERAMIK STUDIO MANDIRI DENGAN TEMA TRADISI LOKAL INDONESIA MELALUI PENDEKATAN ‘ATUMICS’
Authors: Ardini Sasanti Puri , Winata Gita
Published: December 2023

Indonesia, known for its rich cultural diversity and traditional practices, offers a wide range of ceramic

products that have a strong basis in tradition. These creations appear from the artistic endeavors of

individual artists, independent studios, and craft-based industries. The scope of diversity extends beyond

the topic of the field of tradition, which includes a combination of technical abilities and materials used

for the creation of a piece, thus implementing a transformation of a local tradition into an innovative

and creative product. This article present an exhibition and analysis of independent studio and craftbased industries ceramics products that explore the theme of local Indonesian traditions through the

application of the The ATUMICS method is a way of Transformation Tradition that was introduced by

Adhi Nugraha. The study using the ATUMICS framework, which refers Artifact (A), Technique (T),

Utility (U), Material (M), Icon (I), Concepts (C) and Shape (S). These models were utilized to define

the components that were found in ceramics products originating from three different ceramic studio

or craft-based industries in Indonesia. The research results provide insight into which elements can be

applied and combined through the ATUMICS method to enhance local traditions in ceramics.

Keywords: ceramic, craft, product, tradition, atumics
ENDÜLÜS’TE MULÛKU’T-TAVÂİF’TEN ABBÂDÎLER (1023-1091)
Authors: YALT Sevgi , ADIGÜZEL Adnan
Published: December 2023

ÖZET

Müslümanlar 8. yüzyıl başlarında İber Yarımadasını fethetmişler ve bölgeye Endülüs demişlerdir. Burası Müslümanların hâkim olduğu yüzyıllar boyunca (711-1492) Müslüman, Hıristiyan ve Yahudilerin birlikte yaşadığı bir coğrafya olmuştur. Bölgede Müslümanlarının en güçlü şekilde temsil edildiği ve buradaki İslamlaşmanın gerçekleştiği dönem Endülüs Emevi Devleti’nin hâkim olduğu yıllardır (756-1031). Bu devletin yıkılma sürecine girdiği 11. yüzyıl başlarından itibaren Endülüs’teki Müslümanların hâkim olduğu bölgede dağılmalar başlamıştır. Bu süreçte hemen her şehirde küçük devletler kurulmuştur. Bu anlamda 300-400 bin km karelik küçük bir alanda “mulûku’t-tavâif” denilen birçokları bir şehir ya da kaleden ibaret olan onlarca devletçik ortaya çıkmıştır. Bu çalışmada bu küçük devletlerden (mulûku’t-tavâiften) biri olan, 1023-1091 yılları arasında Endülüs’te İşbîliye merkezli olarak hüküm sürmüş Abbâdî Devleti ele alınmıştır. Bu devlet İşbiliye kadısı Ebû’l-Kasım Muhammed b. Abbâd tarafından 1023 yılında kurulmuş, mülûkü’t-tavâifin en büyüğüdür. Devlet, 1091 yılında Murâbıtlar tarafından yıkılana kadar 68 yıl hüküm sürmüştür. Bu çalışmada devletin ortaya çıkış süreci, siyasi faaliyetleri ve komşu devletlerle ilişkileri ele alınmıştır. Bunun yanında devletin yöneticileri olan İbn Abbâd, Mu‘tazıd, Mu‘temid dönemleri, siyasi olayları anlatılmış, ve Abbâdîlerde idarî ve sosyo-kültürel hayat hakkında bilgi verilmiştir.

Anahtar Kelimeler: Abbâdî, Mu‘tazıd, Mu‘temid, İşbîliye, Mülûkü’t-tavâif
Bir Menzil Kasabasından Sanayi Kentine; Gebze
Authors: CECO Vildan , AYDIN Elif Özlem
Published: December 2023

Gebze, coğrafi konumu itibariyle İstanbul’un Anadolu ile ilişkisini sağlayan ticaret ve ulaşım yolları üzerinde bulunmasından dolayı tarih boyunca önemli bir yere sahip olmuştur. 15. yüzyılda İstanbul’un fethiyle birlikte özellikle doğuya olan seferlerde kullanılan önemli bir menzil kasabası halini alan Gebze, 16. yüzyılda Vezir Çoban Mustafa Paşa tarafından yaptırılan külliye ile askeri, ekonomik ve kültürel yönden önemli bir merkez konumuna gelmiştir. 19. yüzyıl sonlarında İstanbul-Bağdat tren yolunun kent merkezinden uzak bir noktadan geçmesi ulaşım ve lojistik açıdan Gebze’nin menzil kasabası rolünü olumsuz yönde etkilemiş olsa da yerleşimde esas dönüşüm 1960’lı yıllarda İstanbul’daki sanayinin desantralizasyonuyla birlikte başlamıştır.

20. yüzyılın ikinci yarısında bölgede artan sanayi faaliyetleriyle beraber gelen göçle Gebze kontrolsüz ve hızlı bir kentleşme sürecine girmiş ve farklı bir kimlik kazanmaya başlamıştır. Bu durumun olumsuz sonuçları imar faaliyetleri ile giderilmeye çalışılmış, ancak altyapı yetersizliği ile hızla büyüyen yerleşim için bu uygulamalar yetersiz kalmıştır. Yoğun yapılanma baskısı sonucunda kentin sahip olduğu kültürel miras maalesef durumdan olumsuz şekilde etkilenmiştir.

Bu çalışmada Gebze ilçe merkezinde ilgili T.C. Kültür ve Tabiat Varlıklarını Koruma Bölge Kurulu tarafından “Gebze Çoban Mustafa Paşa Külliyesi Koruma Alanı”, “Sultan Orhan Camii ve Çevresi Kentsel Sit Alanı” ile “Etkileme Geçiş Alanı” olarak belirlenen koruma alanlarının genel sorunları ele alınmıştır. 1960’lardan günümüze çalışma alanı kapsamında gerçekleştirilen imar ve koruma faaliyetleri ilgili literatür, Belediye arşivi, İller Bankası arşivi ve Koruma Bölge Kurulu arşivi taramaları yardımıyla irdelenmiştir. Çalışma kapsamında bu imar ve koruma faaliyetlerinin Gebze kent merkezindeki koruma alanlarına olan etki ve katkılarının değerlendirilmesi amaçlanmıştır. Bu amaçla alan çalışması gerçekleştirilmiş, çalışma alanındaki kültürel miras değerlerine dair güncel sorunların tespiti için dokuda mimari analizler yürütülmüş ve analiz verileri değerlendirilmiştir. Literatür-arşiv araştırmaları, gözlem-fotografik tespitler ve analiz verilerine dayanarak çalışma alanının koruma sorunları tespit edilmiş, örneklem sokak ve caddelerde siluet çalışmaları gerçekleştirilmiş ve uygun rehabilitasyon önerileri geliştirilmiştir. İlgili kentsel koruma alanlarının ve çevresinin sürdürülebilirliği konusunda öneriler sunulmuştur.
A Topological Data Analysis of the Protein Structure
Authors: Lamine Zakaria , Mamouni My Ismail , Mansouri Mohammed Wadia
Published: December 2023

Persistent homology is a tool from a set of methods called Topological data analysis, showing until nowadays a lot of success when it comes to application in biology since this latest uses metrics only for measuring similarities, Embedding the geometric details and focusing on the global shape is the key point making the success of persistent homology, this will be investigated in the paper since enormous work already done in the field and results seems to be endless, as an efficient topological data analysis tool. In this work we will be confirming the latest assumption (topology embeds geometry) by displaying the structure of COILED SERINE which is a protein estimated to constitute 3-5 percent of the encoded residues in most genomes, and giving a substitute of the optimal characteristic distance that can be used in the flexibility-rigidity index, a classic method used to simulate molecule movements and flexible behavior, when it comes to atomic rigidity functions. We will also analyze interesting patterns in the binding site of the beta sheet generated from the pdb file 2JOX. We will be detecting and giving a simple description of different patterns generated by using javaplex generating barcodes and linear statistical results as a summary statistics.
The role of oxidative stress levels and S100B levels in children with functional neurological disorder
Authors: Sizer Esra , Çobanoğlu Tuğba , Kaplan İbrahim
Published: December 2023

Background/Aim: Although stressors and traumatic life events are known to be predisposing factors for developing functional neurological disorder (FND), the etiology of the disorder has not been fully elucidated. In this study, oxidative stress parameters and serum levels of S100B protein were investigated in pediatric patients with functional neurological disorder. The association of these parameters with stress factors and traumatic life events was investigated.
Methods: This case-control study included a control group of 35 patients aged 8-18 years and 32 healthy subjects diagnosed with functional neurological disorder. The Childhood Trauma Scale and Dissociative Experiences Scale were applied to both groups. Serum levels of the patient and control groups were compared by blood sampling: total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and S100B.
Results: It was found that the Childhood Trauma Scale total score, emotional neglect, emotional abuse, physical neglect and the Dissociative Experiences Scale were statistically significantly higher in the FND group than in the control group (P˂0.001, P˂0.001, P=0.013, P=0.017, P˂0.001). Stressors were found to be statistically significantly higher in the FND group than in the control group (P=0.020). There was no statistical difference between the FND group and control groups regarding the TAS, TOS, OSI, and S100B levels (P=0.965, P=0.228, P=0.268, P=0.517, respectively).
Conclusion: Our study is the first to investigate TOS, TAS, OSI and S100B in children with FND. In our study, although stressors and traumatic experiences were significantly higher in the functional neurological disorder group compared to the control group according to the stress susceptibility model, contrary to expectations, there was no significant difference in oxidative stress parameters and serum S100B levels. It was thought that the interaction between FND, which is characterized by biopsychosocial interaction and can manifest itself with various clinical symptoms, and stress may not be linear as initially thought, and the interaction between genetic predisposition and environmental factors may play a more complex role. The absence of significant differences observed in oxidative stress parameters and serum S100B levels may suggest that we should focus on different pathways and different potential biomarkers that need to be investigated in the future to understand the etiology and diagnosis of FND. However, the limitations noted above may affect the generalizability of the study findings.
Políticas de la violencia y el habitar: consideraciones sobre los memoriales
Authors: Cuéllar Sánchez Raul Sergio
Published: December 2023

La intención del presente artículo es establecer un puente entre las interpretaciones que se tienen sobre la experiencia estética y vital del habitar y del inhabitar. Se busca articular una crítica al concepto de “habitar” dentro del gremio arquitectónico. A partir de una revisión de la definición de “experiencia”, propuesta por Schiller en Cartas sobre la educación estética del hombre (1794) y lo expuesto por Heidegger en Construir Habitar Pensar (1951) y Ser y tiempo (1927). Se busca exponer cuál es el sentido de la noción del “habitar”, como esto se ha vuelto destino para la practica arquitectonica, y presentar como se ha cuestionado actualmente en el proceso de diseño y materialización de memoriales.
DETERMINING THE KNOWLEDGE LEVELS OF SCIENCE TEACHERS ABOUT LABORATORY USE AND SAFETY
Authors: BİNZET Gün , ÖZSALTIK Ekin CİCİK , ÇOŞKUNTUNCEL Orkun
Published: December 2023

Within the scope of the study, the researchers developed the "Laboratory Use and Safety Knowledge Level Test (LKGBDT)". This was aimed at determining the knowledge level of laboratory use and safety by applying the developed test to
science teachers working in Mersin province and district secondary schools affiliated to the Ministry of National Education Mersin Provincial Directorate of National Education in the 2020-2021 academic year. Additionally, the study
investigated the effect of the teacher's graduation branch, gender, sector, whether there was a laboratory in the place where they worked, whether they had received laboratory training, and their educational status on the knowledge
level test prepared. The "relational survey model" was used as the method in the research. "LKGBDT" and "Personal Information Form" were used as the data collection tools. Data analysis was done using the SPSS package program.
The results showed that the science teachers' knowledge level of laboratory use and safety was at a moderate level, and that there was no statistically significant difference between the scores of the participants in terms of parameters
other than the demographic data that affects this level of knowledge, such as having a laboratory, the district where they worked, and gender.
Seroprevalence of dirofilariasis in dogs in Sukabumi Regency
Authors: Ridwan Yusuf , Sudarnika Etih , Ilyas Abdul Zahid
Published: December 2023

Dirofilariasis is a serious zoonotic disease in dogs. This study aimed to measure the prevalence and determine the risk factors of dirofilariasis in the Sukabumi Regency. A total of 152 blood samples were collected from dogs in two sub-districts in Sukabumi which have different topographic characteristics, namely Jampang Tengan District which is a hilly area, and Cisolok District which is a coastal area. Blood serum was examined using the commercial rapid test kit CHW Ag Test Kit 2.0 ® Bionote to detect the presence of the Dirofilaria immitis adult worm antigen. The results showed that the seroprevalence of dirofilariasis in dogs in the Sukabumi Regency was 20.4%. Areas with hilly characteristics have a higher prevalence of dirofilariasis than coastal areas do. The incidence of dirofilariasis in the Sukabumi Regency was not influenced by sex, method of keeping, or age of the dog.
Pengaruh Lama Penyimpanan dan Metode Pasteurisasi Terhadap Karateristik Fisikokimia Susu Kambing PE di Desa Mujur
Authors: Karni Ine , Komalasari Husnita , Pravitri Kartika , Naufali Muhammad , Agustina Randa Soraya , Nalurita Indah
Published: December 2023

Susu kambing merupakan produk pangan yang memiliki banyak manfaat bagi proses metabolisme tubuh karena mengandung berbagai nutrisi yang baik untuk kesehatan. Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh lama penyimpanan dan metode pasteurisasi terhadap karateristik fisikokimia susu kambing peranakan etawa (PE) di desa Mujur. Metode yang digunakan dalam penelitian ini adalah deskriptif dan eksperimental dengan Rancangan Acak Lengkap dengan pola faktorial yang terdiri dari 2 faktor yaitu pasteurisasi dan lama penyimpanan. Data di analisa menggunakan SPSS dengan uji lanjut Duncan multiple range test (DMRT). Hasil penelitian menunjukkan bahwa faktor penyimpanan menghasilkan pengaruh yang signifikan terhadap parameter pH dan warna susu. Faktor pasteurisasi menghasilkan pengaruh yang signifikan pada parameter viskositas, warna dan TPT. Sedangkan interaksi antara faktor penyimapan dan pasteurisasi memberikan pengaruh yang nyata pada parameter warna dan TPT. Perlakuan terbaik pada penelitian ini adalah perlakuan pasteurisasi HTST dengan penyimpanan 0 hari, karena beberapa karakteristiknya sesuai dengan SNI seperti viskositas (1,57 mPa.s) dan keadaan sampel berdasarkan warna (putih susu), aroma (aroma khas susu kuat), dan kenampakan (homogen). Selain itu memiliki nilai L* sebesar 83,49, nilai a* sebesar -3,58, nilai b* sebesar 3,82 dan nilai hue sebesar -46,95
Peningkatan Literasi Siswa Melalui Program Pojok Baca Oleh Kampus Mengajar 6 di Berbagai Sekolah Dasar
Authors: Marzela Faiza  , Maudina Bunga Khairunnisa  , Muhammad Abdul Gani  , Ririn Farianti  , Riska Rahmawati Hasan  , Sopiana Handita Putri
Published: December 2023

Developing and increasing literacy is one of the problems currently being faced. The lack of interest in literacy and interest in reading, especially among children, is caused by, among other things, excessive use of gadgets. With this problem, it is feared that there will be more and more children who have low interest in reading. This research aims to determine the increase in student literacy among children, especially elementary school students, through one of the prestigious independent campus learning (MBKM) programs, namely the Teaching Campus. This increase in literacy will be carried out through one of the work programs implemented, namely the reading corner. The method used in this research is descriptive research. The locations of this research are several elementary schools in West Nusa Tenggara province. The samples used were 5th grade elementary school students and students. The final result of this activity is an increase in reading interest and literacy levels among students at the elementary school level through the Reading Corner program.
ESTÁGIO SUPERVISIONADO DE INTRODUÇÃO AO CAMPO EDUCACIONAL: VIVÊNCIAS TEÓRICAS E PRÁTICAS
Authors: Marques Valdeize de Sales , Nascimento Eula Regina Lima
Published: December 2023

O presente trabalho visa discorrer sobre as vivências construídas durante o estágio supervisionado realizado no Núcleo de Educação do Campo – NEC da Secretaria Municipal de Educação – SEMED de Castanh
UMA LACUNA ENTRE O QUERER DA MULHER E A EXPECTATIVA DOS OUTROS NO CONTO “O BORDADO” DE MARTA HELENA COCCO: LINHAS E LETRAS ALINHAVADAS POR MULHERES.
Authors: EYNG ELIANE INÊS KULKAMP
Published: December 2023

O trabalho refere-se à temática feminina na literatura mato-grossense produzida por mulheres, construindo personagens femininas representativas e autênticas da sua condição de mulher. A intenção é pes
AUTORITARISMO E VIOLÊNCIA ESTATAL: O CRIME DE DESACATO E A SÚMULA 70 DO TJ/RJ COMO INSTRUMENTOS DE CRIMINALIZAÇÃO DA LIVRE MANIFESTAÇÃO
Authors: França Alexandre Miguel , Madeira Filho Wilson , Hagino Cora Hisae Monteiro da Silva , Borges Nadine Monteiro
Published: December 2023

O trabalho parte de um estudo de caso alargado com o objetivo de estudar o autoritarismo estatal e a violência empregada pelo Estado na repressão a manifestações pacíficas que pediam a compra de vacin
A LEGISLAÇÃO VOLTADA À PROTEÇÃO DA PESSOA COM DEFICIÊNCIA NA LUTA ANTICAPACITISTA: A DEFESA DO DIREITO FUNDAMENTAL À VIDA
Authors: TAVARES FABIANA TEIXEIRA RAMOS , Nascimento Crisóstomo Lima do , Rosa Joel de Sá , QUITETE JOICY DE SOUZA RIBEIRO , ALMEIDA BRAULIO BRASIL DE
Published: December 2023

O direito à vida constitui-se em pressuposto para a consecução de quaisquer outros direitos dos sujeitos. Assim, sem a vida nenhum outro direito poderá ser exercido, bem como nenhum dever poderá ser a
O sistema de defesa colonial na cidade de Belém (PA)
Authors: Norat Roseane da Conceição Costa , Motta Giulia Maia , Costa Marcondes
Published: December 2023

A cidade de Belém/PA, marca a expansão colonial portuguesa que se estenderia ao longo da bacia hidrográfica do rio Amazonas a partir de 1616. Como principal urbe da capitania do Grão-Pará, a cidade fo
O patrimônio cultural e suas múltiplas camadas
Authors: Mühlbauer Clarice Futuro
Published: December 2023

Ultrapassamos a marca dos 30 anos da chamada “Constituição Cidadã”. Pautada na construção de uma sociedade livre, justa e solidária; na promoção do bem de todos, sem preconceitos de origem, raça, sexo
TELETRABALHO, DIVISÃO SEXUAL DO TRABALHO: OS REBATIMENTOS DA REESTRUTURAÇÃO PRODUTIVA NA VIDA DAS MULHERES.
Authors: Quintão Vânia , Valença BARROS, Nívia
Published: December 2023

INTRODUÇÃO
A pandemia do COVID-19 desnudou a tragédia neoliberal que tem devastado a sociedade nas últimas décadas: acumulação flexível, reestruturação produtiva e seus rebatimentos no mundo do trabal
O MERCADO DE INFOPRODUTOS
Authors:   , Andrade Igor de
Published: December 2023

Com a chegada da era digital as possibilidades de crescimento se tornaram
impressionantes, cada dia surge ideias novas para mudar e adaptar tudo ao nosso
redor, o mesmo ocorre com o mercado de trabalho, atualmente já existe uma gama
vasta de oportunidades através do ambiente virtual, indo de pequenas até gigantes
empresas, com inúmeras formas, ferramentas e nichos para trabalhar apenas
utilizando um computador ou celular e uma conexão com a internet, e é visando
evidenciar e ensinar sobre uma das principais formas de trabalho que este trabalho
apresenta o tema mercado de infoprodutos, um novo jeito de comercializar o
conhecimento, com alta taxa de crescimento e pouco custo de criação. Com esse
novo mercado, a experiencia, conhecimento e informação podem se tornar uma
mercadoria de alta lucratividade. Neste trabalho abordaremos todos os pontos
relacionados ao mercado de infoprodutos, bem como seu avanço em meio a situação
de pandemia do COVID-19
A Perplexing Case of Genito-urinary Tuberculosis in an 83-Year-Old Woman with Increased Levels of Tumor Markers: A Case Report
Authors: Voskehat Mkrtumyan , Tamara Harutyunyan , Lilit Meliksetyan , Armen Mkhitaryan , Parandzem Khachatryan
Published: December 2023

Background: Tuberculosis (TB) is a significant global health problem, and extrapulmonary TB can present with no specific clinical or radiographic findings. Genito-urinary TB is often associated with elevated tumor markers and can be misdiagnosed as ovarian/fallopian tube carcinomas, especially in elderly female patients, as genitourinary TB commonly affects women of reproductive age. Objective: We present a rare case of genito-urinary TB in an elderly female patient who was initially misdiagnosed with ovarian cancer with metastasis. Case presentation: An 83-year-old woman with a medical history of diabetes and hypertension presented with complaints of abdominal distension. Diagnostic imaging revealed lesions in the ovaries and omentum and tumor markers were elevated, leading to a suspicion of ovarian cancer with metastases to the omentum. The patient underwent a diagnostic laparotomy and surgical removal of ovaries, fallopian tubes, and the lesion of the greater omentum. However, no malignancy was found during the morphological evaluation. Further histopathological examination confirmed the final diagnosis of genito-urinary tuberculosis, and the patient received anti-TB drugs. The postoperative period was uneventful, and tumor marker levels decreased. Conclusion: As the clinical presentation of genito-urinary TB can mimic ovarian cancer, a histopathological examination should be performed for differential diagnosis, thereby reducing the possibility of inaccurate treatment. This case report highlights the importance of considering genito-urinary TB as a differential diagnosis in elderly female patients presenting with elevated tumor markers, abdominal distension, and suspected genital malignancy. It is crucial to carefully evaluate these cases and explore the possibility of genital TB as an alternative diagnosis, given the overlapping clinical presentation. This highlights the importance of a comprehensive diagnostic approach that includes considering TB in addition to malignancy, even in the context of elderly female patients.
Simulação computacional de radioterapia hipofracionada em pacientes com câncer de mama
Authors: De Pieri Rafaela , De Souza Kock Kelser , Bratti Ana Paula
Published: December 2023

O câncer de mama tem alta incidência no público feminino, além de que, nas últimas décadas, a mortalidade por essa doença vem crescendo progressivamente, tornando-se a segunda principal causa de morte entre as mulheres. A radioterapia é uma alternativa entre os tratamentos do câncer, podendo apresentar-se de maneira convencional, administrada em várias sessões ao longo de semanas, ou hipofracionada com doses maiores de radiação administradas em menos sessões, diminuindo o tempo de tratamento. A tecnologia computacional auxilia na simulação do comportamento das células cancerígenas frente a cada abordagem terapêutica, convencional e hipofracionada, em diferentes dimensões tumorais. A simulação computacional tem sido uma ferramenta útil para analisar o efeito da radioterapia convencional e hipofracionada no volume tumoral. Utilizando o software Matlab R 2016ª e o Simulink, foram criados cenários com base em estudos anteriores, considerando diferentes tamanhos iniciais do tumor. Os resultados da simulação mostraram diferenças significativas na redução do volume tumoral entre os dois métodos de radioterapia. Em todos os casos avaliados, a radioterapia hipofracionada resultou em volumes finais menores em comparação com a radioterapia convencional. Além disso, foi observado que a eficácia da radioterapia hipofracionada dependia da dose de radiação aplicada e dos valores de α/β, sendo mais eficaz em doses com α/β mais elevados. Esses resultados sugerem que a radioterapia hipofracionada é uma abordagem eficaz no tratamento do câncer de mama em diferentes dimensões tumorais.
novo paradigma pós-teísta
Authors: Cugini Paolo
Published: December 2023

Este artigo pretende apresentar e aprofundar a proposta que atende pelo nome de pós-teísmo. Para atingir o objetivo, são examinados os escritos dos principais autores que estão refletindo sobre o que se define a um novo paradigma. Assim, examinam-se as análises de, entre outros: Spong, Lenaers, Arregi, Vigil, Gamberini Fanti, Boff. Após uma breve análise historiográfica do conceito de teísmo, a reflexão se concentra em analisar o destino do cristianismo na atual situação pós-teísta. O sentimento que emerge da análise dos textos é que a proposta pós-teísta saúda definitivamente a leitura teísta que a Igreja propôs nos primeiros séculos do mistério cristão. O caminho que se propõe no novo marco cultural pós-teísta consiste na capacidade de olhar e ir além do cristianismo, da religião e do próprio Deus. Indicações para uma nova espiritualidade capaz de integrar a contribuição das disciplinas científicas. Na fase final, além da coragem de ter aberto novas perspectivas espirituais, destacam-se algumas limitações na abordagem e na tomada de posições. Interroga-se sobre a falta de escrúpulos com que o pós-teísmo identifica a verdade com a ciência, além de duvidar da reconstrução histórica da evolução do teísmo e seus corolários culturais.

Abstract: This article intends to present and deepen the proposal that goes by the name of post-theism. To achieve the goal, the writings of the main authors who are reflecting on what is defined as a new paradigm are examined. Thus, the analyses of, among others, are examined: Spong, Lenaers, Arregi, Vigil, Gamberini Fanti, Boff. After a brief historiographical analysis of the concept of theism, the reflection focuses on analysing the fate of Christianity in the current post-theistic situation. The feeling that emerges in the analysis of the texts is that the post-theistic proposal definitively greets the theistic reading that the Church proposed in the first centuries of the Christian mystery. The path that is proposed in the new post-theistic cultural framework consists in the ability to look and go beyond Christianity, religion and beyond God himself. The awareness of the epochal cultural turning point we are experiencing leads the authors of post-theism to elaborate indications for a new spirituality capable of integrating the contribution of scientific disciplines. In the final phase, in addition to the courage of having opened up new spiritual perspectives, some limitations in the approach and in taking positions are underlined. One wonders about the unscrupulousness with which post-theism identifies truth with science, as well as harbouring doubts about the historical reconstruction of the evolution of theism and its cultural corollaries.

Keywords: Theism; Paradigm; Dualism; Monism; Christianity.
The increasing of mathematics achievement in cube and cuboids nets using problem based learning models in grade 4
Authors: Rahmasiwi Dwinda Susi , Maharani Swasti , Hartini Suliyawati
Published: December 2023

The purpose of this research is to improve the results of learning mathematics on the material of nets of cubes and blocks in class IV students at SDN Karangtengah Prandon 1 using the Problem Based Learning learning model. This type of research is classroom action research which is carried out in 2 cycles. The subjects used in this study were class IV students at SDN Karangtengah Prandon 1, which consisted of 11 students. The independent variable used in this research is Problem Based Learning and the dependent variable is the result of learning mathematics. The techniques used in this research are tests, observations and interviews. While the analysis techniques used in this study were quantitative and qualitative in the form of observations made and the percentage of student learning outcomes from the pre-cycle and after the cycle. Based on the research results, it can be concluded that learning by using the Problem Based Learning Model in mathematics lessons, the material for nets of cubes and blocks of student learning outcomes can be improved. The increase in learning outcomes in the pre-cycle was 27.2%, the first cycle was 63.6% and the second cycle was 91%. This assessment was said to be successful because the learning outcomes reached the mastery indicator, namely ≥ 80% of the class average with KKM ≥ 70.
First Record of Aedes Japonicus in St. Tammany Parish, Louisiana
Authors: Cawthon Shannon M. O. , Dimise Mollie M. , Frazier Richard
Published: December 2023

Information of species presence and abundance is useful for taking a targeted approach to controlling populations of medically important and nuisance mosquito species. In April 2023, staff at St. Tammany Parish Mosquito Abatement District (STPMAD), in Slidell, Louisiana, identified Aedes japonicus (Theobald, 1901) mosquitoes from a larval sample brought in from the field for identification. Although invasive Aedes species like Aedes albopictus are commonly found in Louisiana, this is the first record of Ae. japonicus in St. Tammany Parish.
Findings in magnetic resonance spectroscopy in patients with Autism spectrum disorder
Authors: Isaac Tenório  , Lara Brandão  , Aderbal Sabrá Filho  , Selma Sabrá  , Thiago Luiz Bandeira  , Isabela Mansur Bandeira  , Ana Maria E. Dias dos Santos  , Nilse Andréia Marcos Manuel  , Paula Pessanha Silva Mitre  , Camila Marques Rebello  , Bruno de Brito Braga  , Luiz Werber Bandeira  , Aderbal Sabra
Published: December 2023

Background: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition that has been the subject of extensive research, including studies using magnetic resonance imaging (MRI) to explore brain metabolites as potential biomarkers. Methods: The objective of our study was to identify brain metabolites using magnetic resonance and proton spectroscopy that could serve as potential markers of ASD (Autism Spectrum Disorder). Results: Magnetic resonance imaging did not reveal any brain morphological changes in ASD patients. However, the patients with ASD exhibited an elevated glutamate peak in 100% of cases. Conclusions: Magnetic resonance imaging combined with cerebellar spectroscopy is an emerging tool for the diagnosis and management of autism. This approach shows promise in enhancing both the diagnosis and treatment of ASD.
Cold units and their relationship with wheat grain yield in the Yaqui Valley, Sonora, Mexico
Authors: María Monserrat Torres-Cruz  , Pedro Félix-Valencia  , Guillermo Fuentes-Dávila
Published: December 2023

Global warming has the potential to cause the reduction of the cold period available during the winter, which may affect the production of wheat and deciduous fruit trees. Wheat requires accumulated cold units (CU) to switch from a vegetative period to a productive one, making the phenological cycle slower and promoting greater productive yield. The objective was to analyze the accumulation of CU and wheat yield during the last five fall-winter agricultural seasons (2018-2019 to 2022-2023) in the Yaqui Valley, Sonora, Mexico. Data of air temperature were obtained from 21 meteorological stations from the network of automatic meteorological stations of the state of Sonora, located in the Yaqui Valley. The number of CU (≤ 10 °C) was calculated for the wheat season (November 15 to April 30) from the years 2018 to 2023, and the grain yield was obtained from the reports by the Agri-Food and Fisheries Information Service. Descriptive statistics of central tendency, dispersion and the Shapiro-Wilk test were performed to determine the normality of the data; also, correlation analysis and the simple linear regression model by least squares were performed. The 2022-23 crop season showed the highest average grain yield (7.79 t ha-1) and the highest average number of CU (882) among the five seasons analyzed. Wheat seasons 2018-2019 and 2019-2020 had an average number of CU lower than 500. The Pearson correlation analysis showed a highly positive correspondence between CU and grain yield. The linear regression model showed that starting from a base of 434 CU, wheat production per hectare would be 5.90 t, and it will increase 214.3 kg for every additional 100 CU.
Incidence and severity of fungal seedling diseases in Tamale central forest nursery, Ghana
Authors: Prince Cobbinah  , Joseph Ndakpe Tindamdo  , Ammal Abukari  , Cosmas S. Abengmeneng
Published: December 2023

Fungal diseases cause serious seedling mortality in nurseries and threaten future seedling production for forest regeneration. To abate this menace, knowledge about them is key. Therefore, this study aimed at determining the incidence and severity of fungal diseases of forest seedlings in the Central Forest Nursery of Tamale, Ghana. Khaya senegalensis, Tectona grandis and Polyalthia longifolia in the nursery were infected with eight fungal pathogens and an unidentified fungus causing leaf blight, wilt, and dumping-off diseases. The pathogens included Rhizoctonia sp., Fusarium sp., Corrynespora sp., Colletotrichum sp., Cercospora sp., Phytophthora sp., Chaetomium sp., and Macrophomina sp. Rhizoctonia was the dominant pathogen isolated from all the leaves of the seedling species. Colletotrichum and Chaetomium were isolated from the leaves of Polyalthia longifolia. Cercospora and an unidentified spp. were found on the stems of Tectona grandis. Fusarium and Phytophthora were respectively found on Polyalthia longifolia and Khaya senegalensis stems. Chaetomium was identified on both Polyalthia longifolia and Khaya senegalensis stems. Cercospora and Fusarium were isolated from the roots of Tectona grandis and Polyalthia longifolia respectively while Macrophomina was associated with both Tectona grandis and Khaya senegalensis roots. Leaf blight recorded the highest disease incidence (76.7%) and affected all the three seedling species. Wilt disease showed low incidence (10.2-15.8 %) among the different seedling species. Dumping-off disease incidence (10.4%) was only recorded in Khaya senegalensis. The severities of the diseases identified were low (1-2) score except leaf blight of Tectona grandis and Polyalthia longifolia recording a moderate (3.0) severity score. It is recommended that appropriate disease management strategies be employed to prevent high incidences and severities.
PENGEMBANGAN MODUL AJAR KURIKULUM MERDEKA BERBASIS STEM-PBL PADA MATERI STATISTIKA
Authors: Kurniawati Yeva , Ummah Sholikatul
Published: December 2023

Penelitian ini bertujuan untuk menghasilkan modul ajar kurikulum merdeka berbasis STEM-PBL pada materi statistika yang layak dari aspek valid, praktis, dan efektif. Penelitian ini dilakukan pada siswa SMA Assa’adah Bungah pada semester genap tahun ajaran 2022/2023. Penelitian ini merupakan penelitian pengembangan dengan model 4D yaitu Define (pendefinisian), Design (perencanaan), Develop (pengembangan), dan Disseminate (penyebaran). Adapun instrumen yang digunakan dalam pengumpulan data penelitian terdiri atas instrumen pengujian kevalidan berupa lembar validasi, istrumen pengujian kepraktisan berupa angket respon guru dan siswa, dan instrumen keefektifan berdasarkan dari hasil asesmen sumatif dan asesmen formatif. Hasil penelitian menunjukkan bahwa modul ajar yang dikembangkan berdasarkan aspek kevalidan memperoleh skor 3,8 yang termasuk kategori sangat valid. Nilai kepraktisan diperoleh dari angket respon guru dengan skor 3,5 dan angket respon siswa diperoleh skor 3,6 dengan kategori sangat praktis. Selanjutnya, aspek keefektifan dari asesmen sumatif diperoleh skor rata-rata 88,7 yang termasuk kategori efektif.

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Kata kunci: Modul Ajar, STEM, Problem Based Learning, Statistika, Kurikulum Merdeka
Апатические расстройства в структуре эндогенной депрессии
Authors: Сорокин Сергей Александрович
Published: December 2023

В обзоре представлена эволюция взглядов отечественных и зарубежных исследователей на структуру и сущность апатии, представлены различные дефиниции этого феномена и попытки определить его место среди других психопатологических симптомов. В научной разработке проблемы апатии выделены следующие основные направления: 1) рассмотрение апатии как самостоятельного варианта аффективного синдрома; 2) переход от дифференциации апатии аффективной и дефицитарной к разграничению апатии депрессивной и органической; 3) дополнение описательного психопатологического подхода при изучении апатии данными психометрического и нейровизуализационного исследования.
Нейробиологический подход к изучению религиозно-мистических переживаний
Authors: Борисова Ольга Александровна , Копейко Григорий Иванович , Малевич Татьяна Владимировна
Published: December 2023

В статье представлен обзор результатов исследований, посвященных нейробиологическим подходам к изучению религиозно-мистических переживаний. Нейротеология претендует на создание нейробиологических моделей религиозной веры, предполагающих каузальную взаимосвязь процессов в головном мозге с духовно-мистическими переживаниями. Проведен анализ существующих данных и гипотез в области нейротеологии с точки зрения методологии научного познания.
Виктор Романович Буцке: от призрения к лечению (к 170-летию со дня рождения)
Authors: Басова Анна Яновна , Кокорина Марина Вячеславовна
Published: December 2023

В.Р. Буцке (1845-1903) - один из крупнейших психиатров и организаторов здравоохранения конца XIX - начала XX в., оказавший огромное влияние на развитие больничной и внебольничной психиатрической помощи в России. В.Р. Буцке был основателем крупнейшей психиатрической больницы России (Алексеевская больница в Москве), одним из создателей трудотерапии, патронажной службы и других новых гуманных форм помощи душевнобольным.
Отечественный и зарубежный опыт нейропсихологической оценки психических функций при синдроме мягкого когнитивного снижения
Authors: Есейкина Любовь Игоревна , Лукин Алексей Владимирович , Плужников Илья Валерьевич
Published: December 2023

Актуальность разработки методик нейропсихологической оценки додементных вариантов мнестико-интеллектуального снижения при старении обусловлена потребностью в ранней диагностике деменций позднего возраста.Цель. Проанализировать изучение синдрома мягкого когнитивного снижения (МКС) отечественными и зарубежными нейропсихологическими методами.Материал. Сообщение 1 содержит вводные замечания о синдроме МКС, описание исследований отечественной нейропсихологической школы, основные подходы к квантификации данного синдрома в рамках количественных исследований и базовые требования, предъявляемые к методикам оценки когнитивной сферы при синдроме МКС.Вывод. Нейропсихологическая диагностика синдрома МКС - необходимый компонент в комплексном клинико-психологическом обследовании пациентов позднего возраста.
Нейроэндокринные аспекты патогенеза и психофармакотерапии панического расстройства
Authors: Павлова Татьяна Алексеевна , Доровских Игорь Владимирович , Горобец Людмила Николаевна
Published: December 2023

Обоснование: в развитии панического расстройства играет роль накопление гормонов стресса - кортизола и пролактина, а также циклические изменения уровня эстрогена.Цель: представить обзор доказательных исследований нейроэндокринных основ патогенеза панического расстройства, доступ к которым получен через базы данных Pubmed и Medline.Результаты: рассмотрены современные взгляды на терапию панического расстройства, в частности на оценку эффективности различных групп антидепрессантов. Приведены данные литературы о возможных нейроэндокринологических и метаболических нарушениях, сопряженных с применением антидепрессантов различного механизма действия. По результатам анализа публикаций показано, что практически все антидепрессанты влияют на уровень пролактина, тиреоидных гормонов, гормонов ГГА-оси и существенно увеличивают риск развития метаболического синдрома и сахарного диабета 2-го типа.
Offerings for Apollo Delphicus in the Year of Dion and the Contribution of Cleomenes II of Sparta
Authors: Oggiano Giorgia
Published: December 2023

The inscription is included among the accounts of the naopoioi of Delphi, which document the offerings for the reconstruction of the temple of Apollo after the catastrophe that struck the site around 373 BCE. The marble slab is part of an archaic temple gutter. The epigraph attests a list of eparchai sent to the sanctuary by Sparta and some citizens between 337/336 and 336/335 BCE. The extraordinary nature of the Spartan offering is due to the mention of King Cleomenes II, who personally donated 510 drachmas to the temple at a decisive moment for Sparta, immediately after the assassination of his rival Philip II of Macedon.
Reconfiguring Ocean Life by Thinking with Oceans and Whales
Witi Ihimaera’s The Whale Rider and Zakes Mda’s The Whale Caller
Authors: Concilio Carmen
Published: December 2023

Whales are stranded along the Atlantic Ocean in North America, the press spread the news in February 2023. Witi Ihimaera’s novel The Whale Rider (1987) frames a similar episode: “Two hundred whales, lifeless on the beach and in the water” (1987, 85). Stranded whales are protagonists in Zakes Mda’s The Whale Caller (2005), too. Here, a whale is the pretext to explore gender issues, role models in traditional indigenous societies, capitalist economy and tourism, the perception of chieftainship, shamans and spirituality. Making use of acoustic ecology (Carson 1955; Shafer 1994), whales ‘speak’ of relations between humans, non-humans (Huggan 2021) and oceans (Regazzoni 2022).
Analyse sémantique de la liberté de Stella à la Niña Estrellita
Authors: Boraso Silvia
Published: December 2023

A novelist and intellectual that shaped with his writings the twentieth-century Francophone literary panorama, Jacques Stephen Alexis is a writer who needs no introduction. In his theorization of the novel, Alexis has had the great merit, among other things, of recognizing the role played by the first Haitian novelists in the evolution of the country’s literary production. Although he – like most critics, by the way – passes a very negative judgment on certain authors, Alexis nevertheless manages to overcome the tenacious prejudice of their alleged lack of Haitianity and pays tribute to their works, whose literary value has long been overlooked. One example among many: when one speaks of the origins of Haitian literature, one must, for obvious historical reasons, citeStella(1859), the first novel written by a Haitian writer; however, the specialists who have been able to go beyond this mere historical dimension have been few. Alexis, on the other hand, has gone so far as to claim that it is “the bold beginning of marvellous realism”. Without going so far as to considerStellaas the first example of réalisme merveilleux, this article will draw on Alexis’s critical reflection and focus on the possibility of identifying common elements between his prose and Bergeaud’s. In particular, it will propose a cross-reading ofStellaandL’Espace d’un cillementbased on the figure of the two heroines, Stella and La Niña Estrellita respectively, and establish a kind of semantic continuity based on the image of freedom, an image they are the embodiment of.
Sara Del Rossi. Où va le ‘kont’? Dynamiques transculturelles de l’oraliture haïtienne
Authors: Boraso Silvia
Published: December 2023

Compte rendu de Del Rossi, S. (2022). Où va le ‘kont’ ? Dynamiques transculturelles de l’oraliture haïtienne. Paris : L’Harmattan, 234 pp.
Atmane Bissani, Francesca Todesco, Anna Zoppellari. « L’écriture de la ville maghrébine dans l’imaginaire littéraire du Maghreb : représentations romanesques et enjeux esthétiques »
Authors: Ravera Elena
Published: December 2023

Compte rendu de Bissani, A. ; Todesco, F. ; Zoppellari, A. (éds) (2022). « L’écriture de la ville maghrébine dans l’imaginaire littéraire du Maghreb: représentations romanesques et enjeux esthétiques ». Num. monogr., Interfrancophonies, 13, 132 pp.
In Memory of David Fennario (1947-2023)
Authors: Galli Mastrodonato Paola Irene
Published: December 2023

David Fennario was not only an author. He was a militant and an activist for social change, and as such he took no easy byways to make the audience remember the terrifyingly unequal and discriminatory world we live in. His dialogues are powerful, raw and gritty, spoken by unsubmissive subjects who want to deliberately shock the public into awareness.
Machine Learning-Enhanced Geographically Weighted Regression for Spatial Evaluation of Human Development Index across Western Indonesia
Authors: Firmansyah Gustian Angga , Zeniarja Junta , Azies Harun Al , Winarno Sri , Ganiswari Syuhra Putri
Published: December 2023

The HDI (Human Development Index) is one of the important components to measure the level of success in efforts to improve the quality of human life. The human development index is built with three dimensions, namely the longevity and health dimension, the knowledge dimension and the decent standard of living dimension. The longevity and health dimension is measured using Life expectancy at birth. The knowledge dimension is measured using expected years of schooling and average years of schooling. Meanwhile, the decent standard of living dimension is measured using Adjusted per capita expenditure. This study aims to find factors that influence HDI (Human Development Index) in Western Indonesia Region using machine learning models. The results obtained are that HDI is influenced by average years of schooling, expected years of schooling, Life expectancy at birth, and Adjusted per capita expenditure which are sorted from the most significantly influential. The model used in this study is GWR (Geographically Weighted Regression) with evaluation results including, AIC of 215.3162, AICc of 226.5107, and the accuracy level in the form of R-square of 99.38% which means this model is good to use.