bluuebunny/crossref_metadata_2025 huggingface dataset:
Parent and Young Adolescent Connection Speaking Heart-to-Heart
Authors: Rooks-Weir Evelyn , Hilliker Alden
Published: December 2020

The purpose of the Parent And Young Adolescent Connection, Speaking Heart-To-Heart curriculum is to enhance the qualities of strong families among those families with at least one member in the ten-through-fourteen age range.

https://edis.ifas.ufl.edu/4h166
[AG409] Biology and Management of Whitehead Broom in Pastures
Authors: Sellers Brent A. , Butler Lauren D. , McWhorter James
Published: December 2020

Whitehead broom (Spermacoce verticillata; Figure 1), also known as shrubby false buttonweed or southern larraflower, is becoming problematic in south Florida pastures, hayfields, and rights-of-way.  With the first recorded herbarium specimen dates back to 1956, this plant was likely introduced into Florida during the late 1940s or early 1950s.  Since this time, it has increased in cover throughout central and south Florida and has become a serious problem in pastures and hayfields.  To date, there are few options for control of this species.
2011 BEEF FORAGE SURVEY RESULTS
Authors: Crawford Sonja C. , Kirby Christa L. , Prevatt Tycee , Sellers Brent A. , Silveira Maria L. , Stice Bridget C. , Vendramini Joao , Wiggins Lindsey F.
Published: December 2020

The University of Florida / IFAS South Florida Beef Forage Program (SFBFP) is composed of county Extension faculty and state specialists.  The members, in conjunction with the UF/IFAS Program Evaluation and Organizational Development unit, created a survey in 1982, which is used to evaluate ranch management practices.  The survey is updated and distributed every 5 years to ranchers in 14 South Florida counties: Charlotte, Collier, DeSoto, Glades, Hardee, Hendry, Highlands, Hillsborough, Lee, Manatee, Martin, Okeechobee, Polk, and Sarasota.  The responses are anonymous.
Nutrition at early stages of life determines the future growth and reproductive performance of beef calves
Authors: Moriel Philipe
Published: December 2020

Metabolic imprinting is the process by which calf nutrition, during first few months of life, may permanently affect the metabolism and performance of beef steers and heifers. Early-exposure to high-concentrate diets may enhance growth performance of beef steers, as well as, enhance the growth performance and accelerate puberty achievement of beef heifers. Identifying strategies that can enhance calf performance during early postnatal life may provide unique opportunities to optimize feed resources and increase the profitability of beef cattle operations.
Water Management District Considerations for Florida Citrus Groves
Authors: Boman Brian , Parsons Larry
Published: December 2020

This is document No. CH192 and Circular 1422, one of a series of the Agricultural and Biological Engineering Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Publication date: September 2002.
Key Plant, Key Pests: Oak (Quercus spp.)
Authors: Popenoe Juanita , Warwick Caroline R. , Dale Adam , Huo Alfred
Published: December 2020

This series of Key Plant, Key Pests publications is designed for Florida gardeners, horticulturalists, and landscape professionals to help identify common pests associated with common Florida flora. This new 9-page publication provides information and general management recommendations for borers, caterpillars, insect-induced galls, twig girdlers, oak leaf blister, root and butt rot, Tubakia leaf spot, mistletoe, psocids, lace bugs, woolly aphids, powdery mildew, Spanish and ball moss, and lichens. Written by Juanita Popenoe, Caroline R. Warwick, Adam G. Dale, and Alfred Huo, and published by the UF/IFAS Environmental Horticulture Department.https://edis.ifas.ufl.edu/ep596
Biology and Management of Florida Betony (Stachys floridana) in Ornamental Plants in Landscape Planting Beds
Authors: Smith Thomas , Marble Chris
Published: December 2020

Florida betony (Stachys floridana) is a perennial weed in Florida landscape planting beds, gardens, turfgrass, and agricultural production systems. This new 4-page article is written for green industry professionals and others to aid in the identification and management of Florida betony in and around ornamental plants in landscape planting beds. Written by Thomas Smith and Chris Marble, and published by the UF/IFAS Environmental Horticulture Department.https://edis.ifas.ufl.edu/ep597
An Informational Guide to Common Stony Corals of Florida
Authors: Henry Joseph , Yanong Roy P. , McGuire Maia , Patterson Joshua T.
Published: December 2020

The following information is meant to be a guide to Scleractinian (stony) corals of Florida. All corals presented in this paper are in a protected status under Florida’s Coral Reef Protection Act and several of these species are federally protected under the Endangered Species Act. In their natural environment, these corals should never be handled or touched in any form.
Manual de los Reglamentos del Agua de Florida: Departamento de Agricultura y Servicio al Consumidor
Authors: Olexa Michael T. , Minton Laura , Miller Dulcy , Corbett Sarah
Published: December 2020

Este es el documento EDIS FE075, una publicación del Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. Publicada Noviembre 2002.
Manual de los Reglamentos del Agua de Florida: Reglamento Privado
Authors: Olexa Michael T. , Minton Laura , Miller Dulcy , Corbett Sarah
Published: December 2020

Este es el documento EDIS FE077, una publicación del Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. Publicada Noviembre 2002.
Manual de los Reglamentos del Agua de Florida: Plaguicidas
Authors: Olexa Michael T. , Minton Laura , Miller Dulcy , Corbett Sarah
Published: December 2020

Este es el documento EDIS FE088, una publicación del Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. Publicada Noviembre 2002.
Cost of Production for Fresh Grapefruit Grown in Indian River, 2015/16
Authors: Singerman Ariel
Published: December 2020

This article presents a summary of the costs of production for Fresh Grapefruit in the Indian River region during 2015/16. The methodology used to collect the data consisted of surveying growers directly to better reflect growers’ costs. The total cost of production for Fresh Grapefruit in Indian River during 2015/16 was $2,723.88 per acre, down $349.50 per acre relative to the previous season. Reductions in tree replacement and foliar nutritionals expenses account for the bulk of the decrease.
Government Policy and Farmland Markets: Implications of the New Economy--Part 2
Authors: Moss Charles B. , Schmitz Andrew , Goodwin Barry K. , Mishra Ashok K.
Published: December 2020

This is EDIS document FE358, a publication of the Department of Food and Resource Economics, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL. Published October 2002.

https://edis.ifas.ufl.edu/fe358
Enhancing Natural Resource Programs with Field Trips
Authors: Athman Julie , Monroe Martha C.
Published: December 2020

This document is FOR 105, one of a series of the School of Forest Resources and Conservation, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. First published October 2002.

FOR105/FR135: Enhancing Natural Resource Programs with Field Trips (ufl.edu)
Coordinating a Collegiate Service-Learning Mentoring Program
Authors: Rickerson Emily , Ohlson Matthew , Fogarty Kate , Kumaran Muthusami , Pracht Dale
Published: December 2020

Building a program like C.A.M.P. Gator for an institute of higher learning takes a great deal of planning, communication, and leadership. This 3-page fact sheet discusses the steps required to coordinate such a program. Written by Emily Rickerson, Matthew Ohlson, Kate Fogarty, Muthusami Kumaran, and Dale Pracht, and published by the UF Department of Family Youth and Community Sciences, August 2011. (Photo © C.A.M.P. Gator)
Sick Day Management for Adults with Diabetes Who Take Insulin
Authors: Gal Nancy , Bobroff Linda B.
Published: December 2020

When people have type 1 or type 2 diabetes and take multiple daily insulin injections, their blood glucose levels can rise drastically due to a cold or another minor illness. This can result in serious health problems. The best way for people with diabetes to prevent a minor illness from becoming a major illness is to have a personalized sick day plan designed with their health care provider before they become ill. This 4-page fact sheet is a major revision that discusses ways in which illness affects diabetes control, development of a sick day plan, times to call your health care provider, checking blood glucose and urine ketones, medicines, and diet.
Money Management/Your Values
Authors: Turner Josephine
Published: December 2020

This document is FCS5236, one of a series of the Department of Family, Youth and Community Sciences, Florida Cooperative Extension Service, IFAS, University of Florida. Publication: December 2002.

https://edis.ifas.ufl.edu/fy535
Citrus Nutrition Management Practices
Authors: Burrow Jamie D. , Vashisth Tripti , Zekri Mongi , Futch Stephen H. , Schumann Arnold
Published: December 2020

This document is a quick guide to citrus nutrient deficiencies and the importance of a balanced nutriton program.
University of Florida Potato Variety Trials Spotlight: ‘LaChipper’
Authors: Mwatuwa Rodrick Z. , Christensen Christian T. , Solano Pam , Zotarelli Lincoln
Published: December 2020

by Rodrick Z. Mwatuwa, Christian T. Christensen, Pam Solano, and Lincoln Zotarelli http://edis.ifas.ufl.edu/hs1297
Striped Mealybug Ferrisia virgata Cockerell (Insecta: Hemiptera: Pseudococcidae)­
Authors: Hodges Amanda
Published: December 2020

Includes: Introduction - Synonymy - Distribution - Description - Biology - Host Plants - Damage - Management - Selected References

Also published on the Featured Creatures website at http://entnemdept.ufl.edu/creatures/orn/mealybug/Ferrisia_virgata.htm
Worker Protection Standard: Additional Requirements for Agricultural Employers of Workers
Authors: Fishel Frederick M.
Published: December 2020

In 1992, the US Environmental Protection Agency (EPA) issued a comprehensive regulation called the Worker Protection Standard for Agricultural Pesticides (WPS). This regulation is primarily intended to reduce the risks of illness or injury to workers and handlers resulting from occupational exposures to pesticides used in the production of agricultural plants on agricultural establishments (i.e., farms, forests, nurseries and enclosed space production facilities, such as greenhouses). The WPS requires agricultural employers to take steps to reduce pesticide-related risks when agricultural workers and pesticide handlers are exposed to these pesticides. The EPA has made several changes to the WPS since it was fully implemented in 1995. On November 2, 2015, the EPA revised the WPS, making significant changes to the rule’s requirements. Most of the revised provisions will become effective January 2, 2017; there are four provisions that are delayed until January 2, 2018. In late 2016, the EPA released the revised “How to Comply Manual” to provide an updated resource. The entire document is posted on their website at https://www.epa.gov/sites/production/files/2016-09/documents/htcmanual_final.pdf. This document will address the additional requirements for agricultural employers of workers under the revised WPS.
Florida CItrus Activity Book
Authors: Burrow Jamie D. , Dewdney Megan M. , Rogers Michael E. , Spann Timothy M. , Vashisth Tripti
Published: December 2020

The Florida Citrus Activity Book is a basic introduction to Florida citrus trees, diseases, and pests. This book is for elementary students.
Responsible Boating Protects Coral Reefs
Authors: Zangroniz Ana , Barry Savanna C. , Hazell Joy
Published: December 2020

This document gives an introduction to the corals and coral reefs of Florida. Ecological and economic information is given, as well as steps to ensure that safe boating practices reduce physical impacts of coral reefs.
Sea Oats, Uniola paniculata
Authors: Miller Debbie , Thetford Mack , Verlinde Chris , Campbell Gabriel , Smith Ashlynn
Published: December 2020

Sea oats occur throughout Florida on beach dunes and beaches and on coastal areas west to Texas and north to Maryland. Sea oats are vital dune builders that accumulate sand and prevent erosion due to wind, waves, and large storms. As sand is trapped by the long leaves of sea oats, vertical growth is stimulated, and rooting occurs at the buried nodes. This plant is extremely drought- and salt-tolerant, grows up to the high tide line of beaches, and propagates both vegetatively and by seed in the wild (Shadow 2007).https://edis.ifas.ufl.edu/sg186

This publication is derived from information in SGEB-75/SG156, Dune Restoration and Enhancement for the Florida Panhandle, by Debbie Miller, Mack Thetford, Christina Verlinde, Gabriel Campbell, and Ashlynn Smith. https://edis.ifas.ufl.edu/sg156.
Prioritizing Citrus Nutrient Management Decisions
Authors: Obreza Thomas A.
Published: December 2020

This document is SL 199, a fact sheet of the Soil and Water Science Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. First printed: January 2003.

https://edis.ifas.ufl.edu/ss418
News Releases and Public Service Announcements
Authors: Telg Ricky
Published: December 2020

You may be called upon to write a news release or public service announcements about your organization’s activities, interesting news, or important events. This 2-page fact sheet provides tips about how to write news releases and PSAs. Written by Ricky Telg and published by the UF Department of Agricultural Education and Communication, August 2011. (Image: Tom Nordlie, IFAS news writer, works on a story. Photo by Tara Piasio)

https://edis.ifas.ufl.edu/wc113
Important Resources for the Development and Sustainability of School Garden Programs
Authors: Diaz John M. , Elsberry Erin
Published: December 2020

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The Leadership Skills Series: Utilizing Videos to Address Leadership Skills
Authors: Sowcik Matthew , Wert Jennifer , Niewoehner-Green Jera
Published: December 2020

This initial publication in the Leaders Skills Series provides Extension professionals with a brief introduction on how to utilize short leadership videos available on the internet to develop specific skills in large or small group settings. The publication also provides an overview of the Leadership Skills Series in Appendix A.
Challenges and Cloud Computing Environments Towards Big Data
Authors: S V N Madupu Kiran Kumar
Published: December 2020

Big Data has terrific influence on scientific discoveries and also value development. This paper presents approaches in data mining and modern technologies in Big Data. Difficulties of data mining as well as data mining with big data are discussed. Some technology development of data mining as well as data mining with big data are additionally presented.
Piso Salarial Profissional Nacional: Enfoque político partidário na valorização do magistério nos Municípios baianos
Authors: Lima Maria José Rocha , Ramos Fernando José Sadio
Published: December 2020

O texto é parte do trabalho de pesquisa realizado em função do doutoramento em Educação pela Universidade Internacional Iberoamericana (UNINI) e expõe a situação do cumprimento da Lei 11.738/2008 que instituiu o PSPN (Piso Salarial Profissional Nacional), nos municípios da Bahia. Demonstra que, mesmo com respaldo financeiro da União, apenas 35,8% dos 417 municípios baianos aplicam integralmente a lei. Relaciona esse percentual ao espectro ideológico dos partidos políticos dos gestores eleitos em 2016, inferindo uma predominância à esquerda, no cumprimento da lei. Finaliza apontando que a situação tende a se agravar frente às incertezas em relação ao futuro do Fundo Nacional de Desenvolvimento da Educação – FUNDEB, cujo prazo expira em dezembro deste ano, exatamente pela estreita dependência entre o financiamento da educação pública básica, o pagamento do PSPN e os recursos do Fundo.
On personal non-property and property rights and responsibilities of parents and children in legislation of Ukraine
Authors:   Academy of the State Penitentiary Service, Chernihiv, Ukraine, N.B. Shamruk , D.M. Kuliok ,   Academy of the State Penitentiary Service, Chernihiv, Ukraine
Published: December 2020

The article presents a general description of the concept of personal non-property and property rights and responsibilities of parents and children in latest conditions in Ukraine. The legislation is noted to provide the concept of property and non-property rights and responsibilities of parents and children in the state and, accordingly, to regulate such relations between them. Under the personal non-property rights of parents the legislator understands the subjective rights of mother and father, enabling their holders to have and exercise non-property rights as a priority over other participants in family relations, the personal non-property rights of the child defines subjective personal rights, the object of which is intangible benefits that arise from birth and cease to reach full capacity, aimed at the normal development and socialization of the child, have a high degree of public interest, which is to control the actions of parents or persons replacing them. Special attention in the article is paid to the property responsibilities of parents and children. It is established that the property responsibilities of parents are a set of statutory legal obligations that arise for parents from birth to adulthood, and may continue in the event of incapacity of an adult child or continued education, provided that parents can provide such assistance, and accordingly the property responsibilities of children – are the obligations that arise in adult children and related to the provision of material support to parents who are unable to work, disabled, or seriously ill and in need of financial assistance. In our opinion, these concepts reveal almost all the opportunities provided by parents and children, which are provided by the legislator to resolve disputes ans regulate the legal relationship between them. However, we believe that it is necessary to deepen the study of these concepts to further improve them and provide a more detailed definition, while considering all changes in legislation, case law, the opinion of scholars and changes in public life. Key words: parents, children, personal non-property rights, personal non-property responsibilities, personal property rights, personal property responsibilities.
Single and Hybrid Nanofluids to Enhance Performance of Flat Plate Solar Collectors: Application and Obstacles
Authors: Al-Yasiri Qudama , Szabó Márta , Arıcı Müslüm
Published: December 2020

Solar energy represents the best alternative for traditional energy sources used in many thermal energy systems. Among solar thermal systems, Flat Plate Solar Collectors (FPSCs) are the most utilized type implemented in low and medium-level thermal domestic applications. Recently, the usage of nanofluids (NFs) to enhance FPSCs is one of the newest technologies that has drawn the attention of researchers to improve the overall thermal efficiency of solar systems. This paper briefly reviews the recent studies carried on thermal performance enhancement of FPSCs by implementing NFs (single and hybrid NFs) considering the main influential parameters such as particle concentration, particle size, and collector area. Finally, the main obstacles reported by the researchers such as the instability, viscosity, concentration limit, corrosion effect and others are identified, which is believed to be useful for interested newcomers in this research area. Based on the studies investigated in this paper, NFs, even under low concentrations, can remarkably improve the energetic and exergetic efficiency of FPSCs.
Integrating L1 into Grammar Teaching as a Remedy for Learners’ Unresponsiveness in an ESP Classroom: An Action Research
Authors: ÇELİK Handan
Published: December 2020

In this study, the researcher had a group of unresponsive learners taking a year-long English for Specific Purposes (ESP) course in Banking and Finance Department. After the detection of the problem, unresponsiveness, one-on-one semi-structured interviews were conducted with the learners (N=8) to find the reasons of it, and what they needed accordingly. Data analysis showed they majorly needed Turkish- (L1), which was restricted to the teaching of grammar as they found most beneficial to their learning. Thus, use of L1 for explicit grammar teaching which proceeded schema building plus implicit inferring was examined to see if and how it remedied their unresponsiveness. Systematic data collection included the learners’ end-of-course written reflections (N=40) and another round of one-on-one semi-structured interviews (N=7) to further elicit their views about teaching grammar through L1. The results revealed positive evaluations regarding the benefits of L1 upon more and better input comprehension, vocabulary and grammatical knowledge development, and awareness regarding language learning. They also reported feeling less anxious and stressed, which encouraged their willingness to communicate and participate. Thus, the results verify judicious role of L1 as a scaffold to decrease affective barriers and increase comprehension in language learning.
Produção de vídeos como ferramenta de ensino de química a partir da temática da automedicação
Authors: Rosado Vagner Darlane Fortes , Salgueiro Andréia Caroline Fernandes , Folmer Vanderlei
Published: December 2020

Trata-se de uma proposta de ensino utilizando Tecnologias Digitais (produção de vídeos), baseada em uma sequência didática que aborda a composição química e o metabolismo de medicamentos por meio do tema automedicação. Participaram 46 alunos da 3ª série do ensino médio de uma escola pública estadual. A proposta foi implementada em duas etapas. Na primeira, os estudantes pesquisaram, através da aplicação de um questionário, sobre a prática de automedicação entre família e comunidade. Na segunda etapa, foram problematizadas as repercussões da prática da automedicação para a saúde, estudando as estruturas químicas dos medicamentos mais utilizados, bem como sua metabolização. A partir disso, os estudantes foram orientados a produzir vídeos sobre os medicamentos mais utilizados, considerando os aspectos problematizados e estudados. A análise dos questionários mostra o consumo de medicamentos como prática comum entre os entrevistados. Os estudantes apresentaram conhecimento fragmentado sobre o assunto, com poucas informações sobre o uso racional de drogas. A abordagem através da produção de vídeos foi apontada pelos estudantes como desafiadora e importante para uma aprendizagem eficaz. O estudo das drogas no cotidiano, como a automedicação, é de suma importância para a formação de cidadãos críticos e reflexivos, pois envolve a realidade e as implicações para a saúde. Em relação ao conhecimento químico e à produção de vídeos, entendemos que a estratégia serviu como articuladora da aprendizagem, possibilitando a interação entre o conhecimento formal e o mundo.
Percepções e sentimentos de pacientes em fim de vida: um olhar sobre os cuidados paliativos
Authors: Monteiro Daiane da Rosa , Souza Tabata de Cavatá , Ferreira Michelle Batista , Rigue Andréia Aldair , Trevisan Bibiana Fernandes , Mallmann Francielly Haygertt
Published: December 2020

O câncer é um dos problemas de saúde pública mais complexos da atualidade, sendo responsável por milhões de óbitos por ano no mundo. No momento do recebimento do diagnóstico de câncer o indivíduo depara-se com a fragilidade da sua existência e a possibilidade da morte torna-se presente em seus pensamentos. O cuidado paliativo se caracteriza por cuidados prestados quando não há possibilidades terapêuticas de cura. Associado a este aspecto, cresce a preocupação em relação à compreensão do paciente com a sua doença e tratamento. O estudo objetiva conhecer os sentimentos e percepções do paciente oncológico em cuidados paliativos. Trata-se de uma revisão integrativa, de natureza qualitativa, cuja análise será de abordagem exploratória. O estudo foi composto por sete artigos selecionados nas bases de dados Medline, Pubmed e Scielo no período entre 2010 e 2020. Os estudos apontam que os pacientes apresentam diversos sentimentos e percepções sobre seu estado de saúde, como: insegurança, perda da dignidade, problemas com tomada de decisão, preocupações parentais, redução da qualidade de vida e flutuações de sintomas. Ter conhecimento sobre esses aspectos em um período de vida tão fragilizante pode dar suporte para que novos planos de cuidado possam ser feitos em conjunto com o paciente e sua rede familiar, aliviando o fardo sobre o prognóstico da doença.
Caminhos para abordagem de transtornos mentais nas instituições de ensino: Uma ação em saúde mental com o público infanto-juvenil
Authors: Medeiros Lauany Silva de , Castro Karen Silva de , Moreira Nayara Fernanda Alves , Ferreira Michele Pinheiro , Gouveia Amanda Ouriques de , Borges Renata Campos de Sousa , Santos Valeria Regina Cavalcante , Caldato Milena Coelho Fernandes , Reis Daniele  Lima dos Anjos , Sousa Junior Jose Ronaldo Teixeira de , Paes Carmem Lúcia de Araújo , Gouveia Aline Ouriques de , Silva Laís Araújo Tavares da , Gouveia Alisson Ouriques De
Published: December 2020

Relatar uma educação em saúde, para adolescentes de uma escola pública em um município do interior da Amazônia Brasileira. Trata-se de um relato de experiência de cunho qualitativo, exploratório e descritivo, de caráter crítico-reflexivo, sobre uma intervenção de saúde mental que foi embasado no método da problematização, com aplicação das 05 etapas do Arco de Maguerez. Participaram da ação 50 alunos do 06° ano de ensino fundamental e 24 alunos do 01° ano de ensino médio, totalizando 74 participantes, sendo no total 37 do sexo feminino e 13 do masculino, entre a faixa etária de 13 a 17 anos. Nesse sentido, promoveu-se palestras e a criação de grupos terapêuticos, a fim de prestar uma tenção integral as necessidades individuais de cada aluno. Notou-se um déficit na rede de atenção psicossocial, devido a inexistência de um núcleo de assistência psicológico específico ao jovem, na região. Logo, foi possível detectar possíveis sofrimentos psicológicos e auxiliar junto a coordenação pedagógica.
Suplemento alimentar à base de isolado proteico do soro de leite, probiótico e β-glucana: efeitos nas medidas antropométricas e imunidade em mulheres
Authors: Belloli Orlando Barbieri , Santos Joice Sifuentes dos , Silva José Renato , Scachetti Ivana Stefanini Carreiro , Costa Giselle Nobre , Castro-Gomez Raul Jorge Hernan
Published: December 2020

O mercado de alimentos com propriedades funcionais está em crescente expansão, e esse segmento está muito relacionado às inovações. Neste sentido, produtos contendo proteínas do soro do leite, popularmente conhecidas como “Whey Protein”, ganham cada vez mais espaço no mercado de suplementos alimentares. O objetivo deste trabalho foi elaborar um suplemento alimentar a base de isolado protéico do soro de leite, probiótico Bifidobacterium lactis HN019 e β-glucana e avaliar os seus efeitos sobre os parâmetros antropométricos e níveis de imunoglobulina (IgA) salivar em mulheres praticantes de atividade física. O estudo foi realizado com 24 mulheres, idade média de 61 anos, com rotina de treino de15 minutos de alongamento e 45 minutos intercalados entre exercícios aeróbicos e resistidos. O suplemento alimentar foi administrado uma vez ao dia, por 90 dias. Foram feitas avaliações antropométricas (supra ilíaca, abdômen (mm), tórax, cintura, quadril, circunferência abdominal (cm), % de gordura, massa corporal magra e peso gordo) antes, durante e após a suplementação. A determinação de IgA salivar foi realizada nos mesmos períodos. Os resultados demonstraram que a suplementação aliada a uma rotina de exercícios físicos melhorou significativamente (p<0,05) as variáveis analisadas. Dentre as 9 variáveis antropométricas, 7 apresentaram diferença significativa (p<0,05). Os níveis de IgA apresentaram diferença significativa (p<0,05) entre as avaliações. Assim, o suplemento alimentar elaborado neste estudo, proporcionou melhoras significativas nos parâmetros avaliados, indicando o potencial do produto como promotor de efeitos benéficos no estado de saúde físico, bem como no estado imune do organismo.
Продвижение Большого евразийского партнерства в рамках ЕАЭС: проблемы и перспективы
Authors: Иванцов А. В.
Published: December 2020

В данной статье рассматривается текущее состояние и дальнейшие перспективы интеграционных объединений, а также форматы многостороннего экономического сотрудничества с точки зрения реализации инициативы Большого евразийского партнерства. Автор анализирует опыт крупнейших многосторонних форматов в Евразии – Всеобъемлющего регионального экономического партнерства (ВРЭП), китайской инициативы «Один пояс – один путь», Евразийского экономического союза и др. Автор делает вывод о том, что в нынешнем состоянии экономической сферы Большой Евразии наблюдается институциональная перегруженность, вызванная существованием ряда параллельно развивающихся интеграционных проектов и механизмов экономического сотрудничества. Усиление ЕАЭС как институционального центра Большой Евразии может стать базисом для формирования сбалансированного нормативного мега пространства. Однако совокупный экономический потенциал государств – участников ЕАЭС не позволяет Союзу быть крупнейшим экономическим полюсом и ведущим центром развития многосторонних институтов в Большой Евразии. Предполагается, что решением в этой ситуации могло бы стать развитие Всеобъемлющего евразийского партнерства в сторону сопряжения ЕАЭС и ВРЭП – крупнейшего формата выработки правил международного экономического взаимодействия в Азии и формулирования конкретных предложений по выстраиванию системы взаимовыгодных отношений между крупнейшими игроками Евразии, в которую все заинтересованные государства будут вовлечены на взаимовыгодных условиях для укрепления международного сотрудничества
Modeling Strategies of Ductile Masonry Infills for the Reduction of the Seismic Vulnerability of RC Frames
Authors: Milanesi Riccardo R. , Hemmat Mehdi , Morandi Paolo , Totoev Yuri , Rossi Andrea , Magenes Guido
Published: December 2020

The threat to human lives and the economic losses due to high seismic vulnerability of non-engineered traditional masonry infills subjected to earthquakes have been highlighted by several post-seismic surveys and experimental and numerical investigations. In the past decades, researchers have proposed different techniques to mitigate problems related to the seismic vulnerability of traditional masonry infills; however, a viable, practical, and universally accepted solution has not been achieved yet. Among the possible innovative techniques, the one using ductile (or pliable) infills have shown promising results in recent experimental tests. These infills have provided, indeed, a reduced in-plane stiffness and a very high displacement capacity. The research units of the University of Pavia/EUCENTRE (Italy) and the University of Newcastle (Australia) have proposed two different systems for ductile masonry infill based on dividing the masonry panel into a number of segments interconnected through horizontal sliding joints. The ductile masonry infill proposed by the University of Pavia subdivides the masonry panel into four horizontal subpanels using specially engineered sliding joints and presents a deformable mortar at the infill/structure interface, while the one conceived by the University of Newcastle is made of mortar-less specially shaped masonry units capable of sliding on all bed joints. The experiments conducted on the two novel systems have permitted the calibration of two numerical macromodels capable to replicate the overall in-plane seismic response of these ductile masonry infills. One approach is based on a spring model, as usually adopted for traditional masonry infill; the other calibrates the response of a semi-active damper model. The calibrated macromodel approaches have been adopted to demonstrate the enhanced behavior and the reduction of the seismic vulnerability of reinforced concrete (RC) framed structures with the employment of the ductile infills in comparison to structures with non-engineered masonry infills.
New Percutaneous Options for Tricuspid Intervention: How to Identify the Good Clinical Candidate
Authors: Laricchia Alessandra , Khokhar Arif A. , Giannini Francesco
Published: December 2020

The tricuspid valve has been neglected for a long time and severe tricuspid regurgitation (TR) was largely undertreated in the past due to a high operative risk. In the last years we observed the development of different less invasive percutaneous options to treat TR. Currently, percutaneous treatments are reserved for high-risk patients presenting with advanced stage disease by which time they are likely to derive a partial benefit at best. There is a limited evidence base, including no randomized trials, to guide the management strategy for severe TR. In the interim we feel that choosing the best device for the most appropriate clinical candidate and with an adequate timing (most probably an “earlier” timing) will be the key combination to improve early and late outcomes of percutaneous treatments.
Relationship Between Type 2 Diabetes and White Matter Hyperintensity: A Systematic Review
Authors: Wang Dan-Qiong , Wang Lei , Wei Miao-Miao , Xia Xiao-Shuang , Tian Xiao-Lin , Cui Xiao-Hong , Li Xin
Published: December 2020

White matter (WM) disease is recognized as an important cause of cognitive decline and dementia. White matter lesions (WMLs) appear as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans of the brain. Previous studies have shown that type 2 diabetes (T2DM) is associated with WMH. In this review, we reviewed the literature on the relationship between T2DM and WMH in PubMed and Cochrane over the past five years and explored the possible links among the presence of T2DM, the course or complications of diabetes, and WMH. We found that: (1) Both from a macro- and micro-scopic point of view, most studies support the relationship of a larger WMH and a decrease in the integrity of WMH in T2DM; (2) From the relationship between brain structural changes and cognition in T2DM, the poor performance in memory, attention, and executive function tests associated with abnormal brain structure is consistent; (3) Diabetic microangiopathy or peripheral neuropathy may be associated with WMH, suggesting that the brain may be a target organ for T2DM microangiopathy; (4) Laboratory markers such as insulin resistance and fasting insulin levels were significantly associated with WMH. High HbA1c and high glucose variability were associated with WMH but not glycemic control.
Diffusion of Social Information in Non-grouping Animals
Authors: Tóth Zoltán , Jaloveczki Boglárka , Tarján Gergely
Published: December 2020

Recent findings indicate that the utilization of social information, produced inadvertently by other individuals through their spatial location and/or interaction with the environment, may be ubiquitous in the animal kingdom. If so, social information-mediated effects on population growth and interspecies interactions may be more prevalent than previously thought. However, little is known about how social information may spread among non-grouping individuals, i.e., in animals that do not form cohesive groups and therefore social attraction among group-mates does not facilitate information diffusion. Are there any perception-related, temporal, and/or spatial parameters that may facilitate or limit the spread of social information in temporary aggregations or among dispersed individuals in a population? We argue that living in cohesive groups is not necessarily required for the diffusion of social information and for social information-mediated effects to emerge in a population. We propose that while learning complex problem-solving techniques socially is less likely to occur in non-grouping animals, the spread of adaptive responses to social stimuli, especially to non-visual cues, can be common and may affect population, and/or community dynamics in a wide range of taxa. We also argue that network-based diffusion analysis could be a suitable analytical method for studying information diffusion in future investigations, providing comparable estimations of social effects on information spread to previous studies on group-living animals. We conclude that more studies are warranted to verify what intrinsic and extrinsic factors influence information propagation among incidentally and/or indirectly interacting individuals if we are to better understand the role of social information in animal populations and how the social and ecological characteristics of species are related to information spread in natural communities.
Anxiety, Practice Modification, and Economic Impact Among Iraqi Dentists During the COVID-19 Outbreak
Authors: Mahdee Anas F. , Gul Sarhang S. , Abdulkareem Ali A. , Qasim Syed Saad B.
Published: December 2020

Objectives: As health care workers on the front line during the coronavirus (COVID-19) pandemic, dental practitioners are amongst those at risk due to their close contact with potentially infected individuals. The aim of the current study was to assess the anxiety, awareness practice modification, and economic impact amongst Iraqi dentists whilst working during the outbreak.

Methods: This study was performed using an online survey questionnaire with aid of Google forms from 2nd to 23rd July 2020. A total of 484 clinicians responded. The questionnaire was composed of open end, closed end, and Likert five-point scale questions to assess anxiety, awareness and financial impact of COVID-19 on dentists. Mann–Whitney test was used to compare two groups, whilst Kruskal–Wallis was performed by post-hoc test for multigroup comparisons.

Results: The mean age of participants was 36.51 ± 9.164 years and the majority (75.2%) of these were graduate dentists only. More than 80% of participants reported anxiety of catching COVID-19. The recorded anxiety level was higher amongst younger dentists and females. Awareness and practice levels among these dentists of precautions and infection-control measures associated with COVID-19 (94%) was found to be high and to be statistically significantly affected by age, qualification and designation (except GP vs. Specialist). With respect to the economic impact, about 75% of practitioners, regardless of demographical variables, reported that their income had declined by about 50%.

Conclusions: The investigation provides clear insights into the anxiety, practice modifications and economic impact on dentists working in Iraq. Although there is a high level of knowledge and awareness of required practice regarding the COVID-19 outbreak among Iraqi dentists, they also reported a high level of anxiety.
Targeting MicroRNA-125b Promotes Neurite Outgrowth but Represses Cell Apoptosis and Inflammation via Blocking PTGS2 and CDK5 in a FOXQ1-Dependent Way in Alzheimer Disease
Authors: Zhuang Jingcong , Chen Zhongjie , Cai Pingping , Wang Rong , Yang Qingwei , Li Longling , Yang Huili , Zhu Renjing
Published: December 2020

This study aimed to explore the molecular regulatory network among microRNA-125b (miR-125b), forkhead box Q1 (FOXQ1), prostaglandin-endoperoxide synthase 2 (PTGS2), and cyclin-dependent kinase 5 (CDK5), as well as their effects on cell apoptosis, neurite outgrowth, and inflammation in Alzheimer disease (AD). Rat embryo cerebral cortex neurons and nerve growth factor–stimulated PC12 cells were insulted by Aβ1−42 to construct two AD cellular models. Negative control (NC) inhibitor, miR-125b inhibitor, NC siRNA, FOXQ1 siRNA, PTGS2 siRNA, and CDK5 siRNA were transferred into the two AD cellular models alone or combined. Then, cell apoptosis, neurite outgrowth, proinflammatory cytokines, miR-125b, FOXQ1, PTGS2, and CDK5 expressions were detected. MiR-125b inhibition facilitated neurite outgrowth but suppressed cell apoptosis and proinflammatory cytokines (tumor necrosis factor-α, interleukin 1β, and interleukin 6); meanwhile, it upregulated FOXQ1 but downregulated PTGS2 and CDK5. Furthermore, FOXQ1 inhibition promoted cell apoptosis and proinflammatory cytokines but repressed neurite outgrowth; PTGS2 inhibition achieved the opposite effects; CDK5 inhibition attenuated cell apoptosis, whereas it less affected neurite outgrowth and inflammation. Notably, FOXQ1 inhibition attenuated, whereas PTGS2 inhibition elevated the effect of miR-125b inhibition on regulating neurite outgrowth, cell apoptosis, and proinflammatory cytokines. As for CDK5 inhibition, it enhanced the effect of miR-125b inhibition on regulating cell apoptosis, but less impacted the neurite outgrowth and proinflammatory cytokines. Additionally, PTGS2 inhibition and CDK5 inhibition both reversed the effect of FOXQ1 inhibition on regulating cell apoptosis, neurite outgrowth, and proinflammatory cytokines. In conclusion, targeting miR-125b alleviates AD progression via blocking PTGS2 and CDK5 in a FOXQ1-dependent way.
Experimental Evidence of the Benefits of Acupuncture for Alzheimer's Disease: An Updated Review
Authors: Yu Chao-Chao , Du Yan-Jun , Wang Shu-Qin , Liu Le-Bin , Shen Feng , Wang Li , Lin Yuan-Fang , Kong Li-Hong
Published: December 2020

As the global population ages, the prevalence of Alzheimer's disease (AD), the most common form of dementia, is also increasing. At present, there are no widely recognized drugs able to ameliorate the cognitive dysfunction caused by AD. The failure of several promising clinical trials in recent years has highlighted the urgent need for novel strategies to both prevent and treat AD. Notably, a growing body of literature supports the efficacy of acupuncture for AD. In this review, we summarize the previously reported mechanisms of acupuncture's beneficial effects in AD, including the ability of acupuncture to modulate Aβ metabolism, tau phosphorylation, neurotransmitters, neurogenesis, synapse and neuron function, autophagy, neuronal apoptosis, neuroinflammation, cerebral glucose metabolism, and brain responses. Taken together, these findings suggest that acupuncture provides therapeutic effects for AD.
Interpretation of Heart Rate Variability: The Art of Looking Through a Keyhole
Authors: Karemaker John M.
Published: December 2020

The heart may be a mirror of the soul, but the human mind is more than its heart rate variability (HRV). Many techniques to quantify HRV promise to give a view of what is going on in the body or even the psyche of the subject under study. This “Hypothesis” paper gives, on the one hand, a critical view on the field of HRV-analysis and, on the other hand, points out a possible direction of future applications. In view of the inherent variability of HRV and the underlying processes, as lined out here, the best use may be found in serial analysis in a subject/patient, to find changes over time that may help in early discovery of developing pathology. Not every future possibility is bright and shining, though, as demonstrated in a fictional diary excerpt from a future subject, living in a society geared toward preventive medicine. Here implanted biochips watch over the health of the population and artificial intelligence (AI) analyses the massive data flow to support the diagnostic process.
Mitochondrial Bioenergetics at the Onset of Drug Resistance in Hematological Malignancies: An Overview
Authors: Barbato Alessandro , Scandura Grazia , Puglisi Fabrizio , Cambria Daniela , La Spina Enrico , Palumbo Giuseppe Alberto , Lazzarino Giacomo , Tibullo Daniele , Di Raimondo Francesco , Giallongo Cesarina , Romano Alessandra
Published: December 2020

The combined derangements in mitochondria network, function and dynamics can affect metabolism and ATP production, redox homeostasis and apoptosis triggering, contributing to cancer development in many different complex ways. In hematological malignancies, there is a strong relationship between cellular metabolism, mitochondrial bioenergetics, interconnections with supportive microenvironment and drug resistance. Lymphoma and chronic lymphocytic leukemia cells, e.g., adapt to intrinsic oxidative stress by increasing mitochondrial biogenesis. In other hematological disorders such as myeloma, on the contrary, bioenergetics changes, associated to increased mitochondrial fitness, derive from the adaptive response to drug-induced stress. In the bone marrow niche, a reverse Warburg effect has been recently described, consisting in metabolic changes occurring in stromal cells in the attempt to metabolically support adjacent cancer cells. Moreover, a physiological dynamic, based on mitochondria transfer, between tumor cells and their supporting stromal microenvironment has been described to sustain oxidative stress associated to proteostasis maintenance in multiple myeloma and leukemia. Increased mitochondrial biogenesis of tumor cells associated to acquisition of new mitochondria transferred by mesenchymal stromal cells results in augmented ATP production through increased oxidative phosphorylation (OX-PHOS), higher drug resistance, and resurgence after treatment. Accordingly, targeting mitochondrial biogenesis, electron transfer, mitochondrial DNA replication, or mitochondrial fatty acid transport increases therapy efficacy. In this review, we summarize selected examples of the mitochondrial derangements in hematological malignancies, which provide metabolic adaptation and apoptosis resistance, also supported by the crosstalk with tumor microenvironment. This field promises a rational design to improve target-therapy including the metabolic phenotype.
WNT Signaling in Hematological Malignancies
Authors: Frenquelli Michela , Tonon Giovanni
Published: December 2020

The role of the WNT signaling pathway in key cellular processes, such as cell proliferation, differentiation and migration is well documented. WNT signaling cascade is initiated by the interaction of WNT ligands with receptors belonging to the Frizzled family, and/or the ROR1/ROR2 and RYK families. The downstream signaling cascade results in the activation of the canonical β-catenin dependent pathway, ultimately leading to transcriptional control of cell proliferation, or the non-canonical pathway, mainly acting on cell migration and cell polarity. The high level of expression of both WNT ligands and WNT receptors in cancer cells and in the surrounding microenvironment suggests that WNT may represent a central conduit of interactions between tumor cells and microenviroment. In this review we will focus on WNT pathways deregulation in hematological cancers, both at the ligand and receptor levels. We will review available literature regarding both the classical β-catenin dependent pathway as well as the non-canonical pathway, with particular emphasis on the possible exploitation of WNT aberrant activation as a therapeutic target, a notion supported by preclinical data.