bluuebunny/crossref_metadata_2025 huggingface dataset:
Malignant neoplasms of the respiratory system as a problem of nowadays
Authors: Feger O.
Published: April 2022

Annotation. Respiratory malignancies (RM) have become one of the most serious threats to public health. For both Ukraine and other countries, this disease is not only a medical but also a social problem. The aim of the study is to analyze the literature on the provision of cancer care in Ukraine and the epidemiological features of RM among the adult population. The materials were domestic and foreign scientific literature, legal documents, as well as medical and statistical data of the National Cancer Registry. Research methods: information-analytical, comparative content analysis. RM is one of the serious diseases that changes the life schedule not only of the patient, but also of the whole family. About 70% of cases of malignant neoplasms (MN) of the lungs, trachea and bronchi are diagnosed with the onset of symptoms, when there are mediastinal or distant metastases. According to the WHO, in the structure of morbidity in the economically developed countries of the world for several years the leading position is occupied by malignant neoplasms of the trachea, bronchi and lungs among men and breast cancer in women. That is, the main problems faced by the world's leading countries in the organization of medical and pharmaceutical care for these patients may to some extent be considered in Ukraine. An extremely important issue for RM is the principle of their early diagnosis. Given the growing incidence of RM, and especially due to oncopathology of the trachea, bronchi and lungs among the general population, a significant number of postoperative complications, the complexity of social adaptation, should be noted along with constant monitoring and implementation of new treatments, development of new postoperative rehabilitation programs. development of an optimized model of medical care for patients with malignant respiratory tumors. Prospects for further development: the obtained data will be used as a basis for forecasting the risk of RM among the population and the allocation of contingents with a high risk of cancer.
SELECTION OF SOFTWARE ON BASE OF FUZZY TOPSIS METHOD
Authors: Salimov Vagif Hasan Oglu
Published: April 2022

The article is devoted to the problem of multi-criteria decision making. As application problem is used the software selection problem. The analysis of existing methods for solving this problem is given. As a method for solving this problem fuzzy TOPSIS (The Technique for Order of Preference by Similarity to Ideal Solution) is proposed. This method is based on ideal solution approach. The issues of practical implementation of this method are discussed in details. The results of the solution test problem at all stages are presented.
OBSTETRICS AND PERINATAL COMPLICATIONS IN PREGNANT WOMEN WITH CHORIOAMNIONITIS
Authors: Vorobey Ludmila  , Gervazyuk Olga  , Fastovec Alexandra
Published: April 2022

Despite the development of innovative technologies, chorioamnionitis remains a pressing problem in modern obstetrics. The aim of our study was to determine the frequency of obstetric and perinatal complications in pregnant women with chorioamnionitis. The objective of our study was to determine the frequency of obstetrics and perinatal complications in pregnant women with chorioamnionitis. Study groups were formed: Group I (main) - 100 pregnant women with chorioamnionitis, Group II (control) - 100 women with physiological pregnancy. The condition of the mother-placenta-fetus system and the functional fetal condition were assessed by Doppler ultrasound and cardiotocography. The analysis of perinatal consequences in pregnant women with chorioamnionitis was performed, in particular, a retrospective study of perinatal mortality. In the main group of patients were observed the structural changes in placenta 3.9 times more than in group II, oligohydramnios and polyhydramnios 6.9 and 5.6 times more, respectively, intrauterine growth retardation stage I was observed in 11.0% of studied in the main group, intrauterine growth retardation stage II and III were found only in pregnant women of group I (54.0% and 6.0%), respectively. In the hemodynamic disorders structure is dominated by stage II, the degree ofdisorders is 62.0%, only in women with chorioamnionitis were observed disorders in the system "mother-placenta-fetus" stage III - 9.0%.Cardiotocography analysis defined signs of fetal cardiac reactivity in 85.0% of patients. The pathological course of childbirth significantly prevailed in the studied of the main group. Intrauterine infection was diagnosed in 21.0% of cases. Early neonatal sepsis was observed in 9 (42.9%) cases, necrotizing enterocolitis in 5 (23.8%) newborns, congenital pneumonia - 7 (33.3%) cases. In the structure of antenatal fetal death, chorioamnionitis in pregnant women was diagnosed in 63.6% of patients, in the structure of early neonatal mortality - 58.3% of cases. The results of the study indicate that intraamniotic infection is a risk factor for the development of pathological pregnancy and labor with relevant perinatal complications.
YAVUZ BAHADIROĞLU’NUN “40 GECEYE 40 MASAL” ADLI KITABININ ÇOCUK EDEBIYATININ TEMEL İLKELERI AÇISINDAN İNCELENMESI
Authors: ÇEÇEN Fatih , KARAKAŞ Rezan
Published: April 2022

Çocuk edebiyatı, çocuğun dünyası ile sınırlı kalmayan, çocuğa kendisiyle dünyasını tanıma ve anlamlandırma imkânı veren okuma kültürünün temel basamağıdır. Çocuk edebiyatı özgün ve nitelikli eserlerle amacına hizmet eder. Eğlendirme, hoş vakit geçirme ve öğretme amacını taşımakla beraber çocuğun dilsel, kişisel, bilişsel ve sosyal gelişimini destekleme amacını taşır. Ana merkezde çocuk unsurunu barındırması bu alanda masal türünü ön plana çıkarmaktadır. Bu çalışmanın amacı Yavuz Bahadıroğlu’nun “40 Geceye 40 Masal” adlı kitabının çocuk edebiyatı ürünlerinde bulunması gereken tasarım ve içerik özelliklerine uygun olup olmadığını ortaya koymaktır. Çalışmada nitel araştırma yönteminin veri toplama tekniklerinden olan doküman incelemesi tekniği kullanılmıştır. Çalışma materyali yazarın “40 Geceye 40 Masal” adlı kitabında yer alan kırk adet masaldan oluşmaktadır. Araştırmada Yavuz Bahadıroğlu’nun çocuk okurlara yönelik yazdığı ve Millî Eğitim Bakanlığınca tavsiye edilen masalların da yer aldığı “40 Geceye 40 Masal” adlı eseri çocuk edebiyatının temel ilkeleri açısından incelenmiştir. Masallar, tasarım ve içerik özellikleri olmak üzere iki başlık altında çözümlenmiştir. Kitap, tasarım özellikleri açısından kapak-cilt, sayfa düzeni, punto, kâğıt, boyut ve resimler; içerik özellikleri açısından ise konu-kurgu, izlek-tema, ileti, dil ve anlatım, eğitsel ve yazınsal özellikler, karakter-kahraman özellikleri ve çevre özellikleri başlıkları altında incelenmiştir. Çalışmada çocuk edebiyatı ürünlerinde bulunması gereken temel ilkelerden hareketle incelemeler temellendirilmiştir. İncelenen masalların çocuk okurlara okuma alışkanlığı kazandırabilecek, edebî ve estetik zevk verecek nitelikte olduğu ayrıca ders kitaplarında okuma metinleri olarak yer verilebilecek uygunlukta olduğu sonucuna varılmıştır.
Resepsi Satire Dunia Politik dalam Novel Sabdo Cinta Angon Kasih Karya Sujiwo Tejo
Authors: Theum Dita Chrysan , Wijaya Putra Candra Rahma
Published: April 2022

Abstract
The reseach paper is entiltled “ Satire Problem Political Indication in Sujiwo Tejo’s Sabdo Cinta Angon Kasih Novel “.Social problems in the political worlda are increasimgly in the spotight in society. This study aims at this first, studying the relevance of the Sabdopalon puppet. Second, being able to understand Sujiwo Tejo’s reception of Sabdo Palon’s characterization. Third, showing how the form criticism for political elite the perspective of phenomenon that is being viral in the form of political problematic satire. This study data source is in the form of quote in the npvel Sabdo Cinta Angon Kasih by Sujiwo Tejo. Data collection techniques by reading in depth and giving a sign. The results of results of the study are in part the following , !) The story of the puppet show Sabdo Palon, 2) The reception of the figure of Sabdopalon in the novel Sujiwo Tejo’s, and 3) Social criticism in the form of satire in the novel Sabdo Cinta Angon Kasih.
 
Abstrak
Penelitian ini berjudul “ Satire Indikasi Problematika Dunia Politik Dalam Novel Sabdo Cinta Angon Kasih Karya Sujiwo Tejo”  dunia politik menjadi sorotan dalam novel ini. Penelitian ini bertujuan untuk ini pertama, mempelajari relevansi pewayangan Sabdo palon. Kedua, mampu menjelaskan resepsi Sujiwo Tejo terhadap penokohan Sabdo Palon..  Ketiga, menunjukan bagaimana bentuk kritikan untuk kaum elit politik dalam prespektif fenomena yang sedang viral dalam bentuk satire problematika politik. Penelitian ini termasuk dalam penelitian deskritif kualitatif dengan menjabarkan hasil analisis berdasarkan teori. Teori yang digunakan ialah teori resepsi sastra melalui pendekatan sosiologi sastra Sumber data berupa kutipan dalam novel Sabdo Cinta Angon Kasih karya Sudjiwo Tejo. Teknik pengumpulan data dengan membaca secara mendalam dan memberikan tanda. Hasil penelitian adalah sebagian berikut 1) Kisah pewayangan Sabdopalon, 2) Resepsi Tokoh Sabdopalon dalam novel Sujiwo Tejo, 3) Kritik sosial berupa satire dalam novel Sabdo Cinta Angon Kasih terhadap problematika perpolitikan yang tengah viral di masyarakat.
CFD Simulation on the Flow Inside a Fish Culture Tank
Authors: Ryan Anugrah Putra  , Shiddiqie Habib Luthfi Ash , Ahmad Hafidh Naufal , Nugroho Akhlisa Nadiantya Aji
Published: April 2022

Aquaculture is an important sector for providing a food source. Technology may help the development of aquaculture including in the design of the fluid flow condition beneficial for aquaculture tank design and its operational parameters. In this study, the use of Computational Fluid Dynamics (CFD) to provide local fluid flow information was demonstrated. In the first case, the fluid flow condition generated by two different inlet orientations, namely the straight inlet and the angled inlet was investigated. The significant difference in the fluid flow pattern was observed by the help of the velocity streamlines. In the second case, the transient CFD simulation was used to determine the transient temperature distribution for the two different inlet orientations. The result also shows the significant different in the distribution which closely related to the generated fluid flow by both inlet orientations.
PENGUATAN STRATEGI KEAMANAN MANUSIA DI PERBATASAN MOTA AIN (INDONESIA) DENGAN BATUGADE (TIMOR LESTE)
Authors: Anna Yulia Hartati  , Ali Martin  , Mario P. Rebelo Soares
Published: April 2022

ABSTRAK

 

Pengelolaan perbatasan Indonesia –Timor Leste yang masih berorientasi pada keamanan teritorial mengindikasikan bahwa negara memandang keamanan perbatasan sebagai sebuah ancaman dari luar sehingga strategi penguatan state security terus dilakukan, di mana peran militer diperkuat untuk mengawal tapal batas. Padahal, persoalan penting yang sangat membutuhkan penanganan sesegera mungkin adalah masalah keamanan manusia seperti kebutuhan akan kecukupan pangan, bebas dari ancaman penyakit, kebodohan, pelanggaran HAM, dan lain sebagainya. Untuk itu, negara perlu memperkuat keamanan individu sebagai cara untuk mempertebal rasa identitas bangsa dan semangat nasionalisme yang akan berdampak pada kesadaran rakyat untuk menjaga keutuhan, keamanan dan kedaulatan negaranya. Artikel ini bertujuan untuk mendiskusikan pentingnya strategi penguatan human security di perbatasan Indonesia – Timor Leste sebagai cara untuk mewujudkan kepentingan nasional. Dengan menggunakan desain studi kasus dan pendekatan kualitatif, tulisan ini berupaya menjelaskan kondisi keamanan manusia di area perbatasan Mota Ain. Beberapa permasalahan seperti rendahnya tingkat kesejahteraan masyarakat menunjukkan buramnya potret keamanan individu di perbatasan kedua negara. Mendasari argumen ini, ada alternatif strategi yang bisa dilakukan pemerintah yaitu menerapkan strategi penguatan human security dalam pengelolaan perbatasan kedua negara. Jadi,komponen yang berperan dalam memelihara keamanan tidak hanya kaum militer, tetapi juga non militer.

Kata kunci: Perbatasan Indonesia-Timor Leste, Pengelolaan perbatasan, Human security.
INSTITUTIONAL VILLAGE STRENGTHENING MODEL IN COMPLETING STANDAR MINIMUM OF HUMAN DEVELOPMENT
Authors: Nurdin Nani Harlinda , Hamson Zulkarnain , Sahur Askariani
Published: April 2022

Abstract: In the current era of village autonomy, one of the things that needs to be studied is the ability of village government human resources to meet development goals, both locally, regionally and nationally. One of the development goals is determined by the success of human development. The fact that there is weak capacity of village government has an impact on the success of overall development. For this reason, this study aims to examine these phenomena. This study used a qualitative approach with the unit of analysis being the village government in Galesong Utara District, Takalar Regency. The research data consisted of primary and secondary data and were processed through data reduction. The results of this study indicate that the human resource capacity of the Dessa government in the District of North Galesong has not been maximized in carrying out the authority of the village so that it has an impact on the success of its development. This can be seen from the three main dimensions of institutional development, namely human resource development, institutional strengthening, and organizational reform. In terms of human resource development, village officials lack experience in making terms of reference for training so that the expected output is not achieved. In terms of organizational strengthening, it has not been implemented because the incentive system, mechanisms and mechanisms for utilization, leadership, and organizational culture are unclear and inadequate except for the management structure. In terms of organizational reform, it shows that it has not been able to adapt to changes because it does not have a program that is prepared to increase institutional capacity and human resources for village development. Thus, the researcher offers a model for implementing village government based on human resource development (HR). This model is expected to provide solutions to the implementation of Village governance in North Galesong District in implementing human development policies which include dimensions of education, health and economy as well as increasing community participation in the success of development programs.
PERFORMANCE OF PUBLIC SERVICES OF THE POPULATION AND CIVIL RECORD SERVICES DURING PANDEMIC
Authors: Septiana Anis , Budiono Pitojo
Published: April 2022

Performance is very important for organizations, especially government organizations. By measuring the performance of an organization, an organization can utilize and improve the effectiveness and efficiency of its human resources, as a basis for distributing awards, assisting in consideration and decision making efforts and identifying training needs and employee resource development. In connection with the existence of the Department of Population and Civil Registry of Bandar Lampung City, one of its main tasks is to make and issue identity cards and to handle personnel resource problems in order to improve the quality of apparatus resources properly and sustainably to support the implementation of the main tasks and functions as well as the achievement of Population work results. and Civil Registry of Bandar Lampung City. In an effort to achieve the work performance of Population and Civil Registry employees of Bandar Lampung City, it includes work motivation, ability, work environment, work discipline, leadership and personality. Based on the data on the website of the population and civil registration office of the city of Bandar Lampung, there are 7244 queues of recording electric ID cards that have not been processed and there are delays in the ID card making process which should have been completed on the specified schedule but has not been completed.
SUMBER DAYA ALAM DALAM PUSARAN PILKADA SERENTAK
Authors: Risal Semuel , Herry Bajari Abner , Hergianasari Putri
Published: April 2022

Demokrasi di Indonesia telah berkembang menjadi “industri politik” yang membutuhkan biaya yang sangat besar untuk berinvestasi. Tujuan penelitian adalah untuk mengeksplorasi tingginya biaya Pilkada langsung yang harus di keluarkan oleh kandidat untuk bertarung dalam kontestasi Pilkada, sehingga menjadi pintu masuk para cukong politik untuk mencari rente melalui Pilkada. Temuan kami menunjukkan bahwa Pilkada telah menjadi arena “pertempuran” antar cukong, dan daerah yang memiliki sumber daya alam yang melimpah menjadi rebutan cukong lokal dan nasional. Mereka bertarung melalui pendanaan dan pembiayaan semua kebutuhan kampanye kandidat. Sehingga pada lokus ini, mereka menguasai sumber daya alam dan merekalah yang menentukan siapa yang akan menjadi bupati, gubernur hingga siapa yang menjadi presiden. Penekanan pada SDA, khususnya tambang batu bara, sebagai salah satu sumber utama pendanaan untuk menggerakkan mesin politik, membawa dampak buruk pada tata kelola sumber daya alam dan lingkungan. Sehingga, isu SDA perlu menjadi agenda dalam setiap proses politik lokal dan nasional dan memutus mata rantai cukong politik dengan penguasa SDA yang transaksional.
EVALUASI KEBIJAKAN WORK FROM HOME BAGI APARATUR SIPIL NEGERI PADA MASA PANDEMI COVID-19 DI BADAN PERENCANAAN PEMBANGUNAN DAERAH KOTA PEKANBARU TAHUN 2021
Authors: Linda Yusnita  , Febriana Rury
Published: April 2022

The implementation of the WFH policy during the Covid-19 pandemic certainly has responsibilities and obligations that are no different from working in an office. However, it can be seen from the fact that in its implementation, WFH cannot be separated from challenges and obstacles that must be faced, this is because not all work can be carried out from home. This study aims to evaluate the implementation of the WFH policy in the Pekanbaru City BAPPEDA work environment during the Covid-19 pandemic. This research uses descriptive qualitative method. The data obtained were sourced from the head of the personnel department at BAPPEDA Pekanbaru City. Data collection was carried out through observation, interviews, and collecting documents supporting the research. The results obtained indicate that based on evaluation activities by paying attention to the 6 (six) evaluation criteria such as effectiveness, efficiency, adequacy, leveling, responsiveness, and accuracy that have been carried out and can be seen where in practice, with the existence of WFH that has not been able to run properly. good and there is a tendency that there is a decline in public services. It can be seen that, there are obstacles from the existence of WFH which include aspects of computer availability, aspects of the ability to master information technology, and aspects of performance appraisal.
Apresentação Formação de professores, perdas y danos:
Authors: Jardilino José Rubens Lima
Published: April 2022

A Formação Docente – Revista Brasileira de Pesquisa sobre Formação de Professores (RBPFP) – é uma publicação do Grupo de Trabalho Formação de Professores (GT8), da Associação Nacional de Pós-Graduação e Pesquisa em Educação (Anped) publicada em parceria com Autêntica Editora. Esta publicação refere-se ao primeiro quadrimestre de 2022 - número 29, do volume 14 (janeiro – abril) de 2022.
Adult diffuse intrinsic pontine glioma: clinical, radiological, pathological, molecular features, and treatments of 96 patients
Authors: Wang Yi , Pan Changcun , Xie Mingguo , Zuo Pengcheng , Li Xiaoou , Gu Guocan , Li Tian , Jiang Zhuang , Wu Zhen , Zhang Junting , Zhang Liwei
Published: April 2022

OBJECTIVE

Unlike its pediatric counterpart, adult diffuse intrinsic pontine glioma (DIPG) remains largely unelucidated. In this study, the authors examined the clinical, radiological, pathological, molecular, and clinical aspects of 96 adult DIPGs.

METHODS

The National Brain Tumor Registry of China (April 2013–December 2019) was used to collect data on radiologically diagnosed adult DIPG patients. Survival analysis was conducted using Kaplan-Meier curves and univariate and multivariate Cox regression. The chi-square test/Wilcoxon rank-sum test and multivariable logistic regression were used to examine the clinical and radiological characteristics of patients with long-term survival (LTS). Interaction analyses between clinical factors were also conducted.

RESULTS

The median age at symptom onset was 33.5 years, and the median duration of symptoms was 4.5 months. The frequencies of H3K27M and IDH1 mutations were 37.2% and 26.5%, respectively. All adult DIPG patients had a median overall survival (OS) of 19.5 months, with 1-, 2-, and 3-year survival rates of 67.0%, 42.8%, and 36.0%, respectively. The median OS of 40 patients who did not undergo treatment was 13.4 months. Patients with H3K27M-mutant tumors had a poorer prognosis than those with IDH-mutant tumors (p < 0.001) and H3K27M(−)/IDH–wild-type tumors (p = 0.002), with a median OS of 11.4 months. The median OSs of patients with H3K27M-mutant tumors who received treatment and those who did not were 13.8 months and 7.5 months, respectively (p = 0.016). Among patients with and without a pathological diagnosis, H3K27M mutation (p < 0.001) and contrast enhancement on MRI (p = 0.003), respectively, imparted a worse prognosis. Treatments were the predictive factor for patients with H3K27M-mutant tumors (p = 0.038), whereas contrast enhancement on MRI was the prognostic factor for the H3K27M(−) group (p = 0.038). In addition, H3K27M mutation and treatment were significant predictors for patients with symptom duration ≤ 4 months (H3K27M, p = 0.020; treatment, p = 0.014) and tumors with no contrast enhancement (H3K27M, p = 0.003; treatment, p = 0.042). Patients with LTS were less likely to have cranial nerve palsy (p = 0.002) and contrast enhancement on MRI at diagnosis (p = 0.022).

CONCLUSIONS

It is recommended that all adult DIPG patients undergo genomic testing for H3K27M and IDH mutations. Despite the low prevalence, additional study is needed to better characterize the efficacy of various treatment modalities in adults with DIPG.
Association between socioeconomic status and presenting characteristics and extent of disease in patients with surgically resected nonfunctioning pituitary adenoma
Authors: Cote David J. , Ruzevick Jacob J. , Kang Keiko M. , Pangal Dhiraj J. , Bove Ilaria , Carmichael John D. , Shiroishi Mark S. , Strickland Ben A. , Zada Gabriel
Published: April 2022

OBJECTIVE

The aim of this study was to evaluate the association between zip code–level socioeconomic status (SES) and presenting characteristics and short-term clinical outcomes in patients with nonfunctioning pituitary adenoma (NFPA).

METHODS

A retrospective review of prospectively collected data from the University of Southern California Pituitary Center was conducted to identify all patients undergoing surgery for pituitary adenoma (PA) from 2000 to 2021 and included all patients with NFPA with recorded zip codes at the time of surgery. A normalized socioeconomic metric by zip code was then constructed using data from the American Community Survey estimates, which was categorized into tertiles. Multiple imputation was used for missing data, and multivariable linear and logistic regression models were constructed to estimate mean differences and multivariable-adjusted odds ratios for the association between zip code–level SES and presenting characteristics and outcomes.

RESULTS

A total of 637 patients were included in the overall analysis. Compared with patients in the lowest SES tertile, those in the highest tertile were more likely to be treated at a private (rather than safety net) hospital, and were less likely to present with headache, vision loss, and apoplexy. After multivariable adjustment for age, sex, and prior surgery, SES in the highest compared with lowest tertile was inversely associated with tumor size at diagnosis (−4.9 mm, 95% CI −7.2 to −2.6 mm, p < 0.001) and was positively associated with incidental diagnosis (multivariable-adjusted OR 1.72, 95% CI 1.02–2.91). Adjustment for hospital (private vs safety net) attenuated the observed associations, but disparities by SES remained statistically significant for tumor size. Despite substantial differences at presentation, there were no significant differences in length of stay or odds of an uncomplicated procedure by zip code–level SES. Patients from lower-SES zip codes were more likely to require postoperative steroid replacement and less likely to achieve gross-total resection.

CONCLUSIONS

In this series, lower zip code–level SES was associated with more severe disease at the time of diagnosis for NFPA patients, including larger tumor size and lower rates of incidental diagnosis. Despite these differences at presentation, no significant differences were observed in short-term postoperative complications, although patients with higher zip code–level SES had higher rates of gross-total resection.
Assessing the differences in operative and patient-reported outcomes between lateral approaches for lumbar fusion: a systematic review and indirect meta-analysis
Authors: Bhatti Atiq ur Rehman , Cesare Joseph , Wahood Waseem , Alvi Mohammed Ali , Onyedimma Chiduziem E. , Ghaith Abdul Karim , Akinnusotu Oluwatoyin , El Sammak Sally , Freedman Brett A. , Sebastian Arjun S. , Bydon Mohamad
Published: April 2022

OBJECTIVE

Anterior-to-psoas lumbar interbody fusion (ATP-LIF), more commonly referred to as oblique lateral interbody fusion, and lateral transpsoas lumbar interbody fusion (LTP-LIF), also known as extreme lateral interbody fusion, are the two commonly used lateral approaches for performing a lumbar fusion procedure. These approaches help overcome some of the technical challenges associated with traditional approaches for lumbar fusion. In this systematic review and indirect meta-analysis, the authors compared operative and patient-reported outcomes between these two select approaches using available studies.

METHODS

Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach, the authors conducted an electronic search using the PubMed, EMBASE, and Scopus databases for studies published before May 1, 2019. Indirect meta-analysis was conducted on fusion rate, cage movement (subsidence plus migration), permanent deficits, and transient deficits; results were depicted as forest plots of proportions (effect size [ES]).

RESULTS

A total of 63 studies were included in this review after applying the exclusion criteria, of which 26 studies investigated the outcomes of ATP-LIF, while 37 studied the outcomes of LTP-LIF. The average fusion rate was found to be similar between the two groups (ES 0.97, 95% CI 0.84–1.00 vs ES 0.94, 95% CI 0.91–0.97; p = 0.561). The mean incidence of cage movement was significantly higher in the ATP-LIF group compared with the LTP-LIF group (stand-alone: ES 0.15, 95% CI 0.06–0.27 vs ES 0.09, 95% CI 0.04–0.16 [p = 0.317]; combined: ES 0.18, 95% CI 0.07–0.32 vs ES 0.02, 95% CI 0.00–0.05 [p = 0.002]). The mean incidence of reoperations was significantly higher in patients undergoing ATP-LIF than in those undergoing LTP-LIF (ES 0.02, 95% CI 0.01–0.03 vs ES 0.04, 95% CI 0.02–0.07; p = 0.012). The mean incidence of permanent deficits was similar between the two groups (stand-alone: ES 0.03, 95% CI 0.01–0.06 vs ES 0.05, 95% CI 0.01–0.12 [p = 0.204]; combined: ES 0.03, 95% CI 0.01–0.06 vs ES 0.03, 95% CI 0.00–0.08 [p = 0.595]). The postoperative changes in visual analog scale (VAS) and Oswestry Disability Index (ODI) scores were both found to be higher for ATP-LIF relative to LTP-LIF (VAS: weighted average 4.11 [SD 2.03] vs weighted average 3.75 [SD 1.94] [p = 0.004]; ODI: weighted average 28.3 [SD 5.33] vs weighted average 24.3 [SD 4.94] [p < 0.001]).

CONCLUSIONS

These analyses indicate that while both approaches are associated with similar fusion rates, ATP-LIF may be related to higher odds of cage movement and reoperations as compared with LTP-LIF. Furthermore, there is no difference in rates of permanent deficits between the two procedures.
Comparison of anterior cervical discectomy and fusion versus artificial disc replacement for cervical spondylotic myelopathy: a meta-analysis
Authors: Chang Chao-Jui , Liu Yuan-Fu , Hsiao Yu-Meng , Huang Yi-Hung , Liu Keng-Chang , Lin Ruey-Mo , Lin Cheng-Li
Published: April 2022

OBJECTIVE

Anterior cervical discectomy and fusion (ACDF) has long been regarded as a gold standard in the treatment of cervical myelopathy. Subsequently, cervical artificial disc replacement (c-ADR) was developed and provides the advantage of motion preservation at the level of the intervertebral disc surgical site, which may also reduce stress at adjacent levels. The goal of this study was to compare clinical and functional outcomes in patients undergoing ACDF with those in patients undergoing c-ADR for cervical spondylotic myelopathy (CSM).

METHODS

A systematic literature review and meta-analysis were performed using the Embase, PubMed, and Cochrane Central Register of Controlled Trials databases from database inception to November 21, 2021. The authors compared Neck Disability Index (NDI), SF-36, and Japanese Orthopaedic Association (JOA) scores; complication rates; and reoperation rates for these two surgical procedures in CSM patients. The Mantel-Haenszel method and variance-weighted means were used to analyze outcomes after identifying articles that met study inclusion criteria.

RESULTS

More surgical time was consumed in the c-ADR surgery (p = 0.04). Shorter hospital stays were noted in patients who had undergone c-ADR (p = 0.04). Patients who had undergone c-ADR tended to have better NDI scores (p = 0.02) and SF-36 scores (p = 0.001). Comparable outcomes in terms of JOA scores (p = 0.24) and neurological success rate (p = 0.12) were noted after the surgery. There was no significant between-group difference in the overall complication rates (c-ADR: 18% vs ACDF: 25%, p = 0.17). However, patients in the ACDF group had a higher reoperation rate than patients in the c-ADR group (4.6% vs 1.5%, p = 0.02).

CONCLUSIONS

At the midterm follow-up after treatment of CSM, better functional outcomes as reflected by NDI and SF-36 scores were noted in the c-ADR group than those in the ACDF group. c-ADR had the advantage of retaining range of motion at the level of the intervertebral disc surgical site without causing more complications. A large sample size with long-term follow-up studies may be required to confirm these findings in the future.
Lumbar dynamic pedicle-based stabilization versus fusion in degenerative disease: a multicenter, double-blind, prospective, randomized controlled trial
Authors: Meyer Bernhard , Thomé Claudius , Vajkoczy Peter , Kehl Victoria , Dodel Richard , Ringel Florian , _ _ , _ _ , Meyer Bernhard , Ringel Florian , Behr Michael , Pape Haiko , Putzier Michael , Schuerings Marc , Thomé Claudius , Hartmann Sebastian , Vajkoczy Peter , Czabanka Marcus , Rohde Veit , von Eckardstein Kajetan , Börm Wolfgang , Zausinger Stefan , Sambale Rafael , Stoffel Michael , Richter Marcus , Arp Mirko , Bostelmann Richard , Meyer Frerk , Weber Fritz , Schulte Tobias , Spetzger Uwe , Müller Andreas , Wirtz Rainer , Dodel Richard , Evers Janis , André Elisabeth , Zollner Alfred , Kehl Viktoria
Published: April 2022

OBJECTIVE

Fusion is the standard of treatment for degenerative lumbar symptomatic instabilities. Dynamic stabilization is a potential alternative, with the aim of reducing pathological motion. Potential advantages are a reduction of surgical complexity and morbidity. The aim of this study was to assess whether dynamic stabilization is associated with a higher degree of functional improvement while reducing surgical complexity and thereby surgical duration and perioperative complications in comparison with lumbar fusion.

METHODS

This was a multicenter, double-blind, prospective, randomized, 2-arm superiority trial. Patients with symptomatic mono- or bisegmental lumbar degenerative disease with or without stenosis and instability were randomized 1:1 to instrumented fusion or pedicle-based dynamic stabilization. Patients underwent either rigid internal fixation and interbody fusion or pedicle-based dynamic stabilization. The primary endpoint was the Oswestry Disability Index (ODI) score, and secondary endpoints were pain, health-related quality of life, and patient satisfaction at 24 months.

RESULTS

Of 293 patients randomized to fusion or dynamic stabilization, 269 were available for analysis. The duration of surgery was significantly shorter for dynamic stabilization versus fusion, and the blood loss was significantly less for dynamic stabilization (380 ml vs 506 ml). Assessment of primary and secondary outcome parameters revealed no significant differences between groups. There were no differences in the incidence of adverse events.

CONCLUSIONS

Dynamic pedicle-based stabilization can achieve similar clinical outcome as fusion in the treatment of lumbar degenerative instabilities. Secondary failures are not different between groups. However, dynamic stabilization is less complex than fusion and is a feasible alternative.
Longitudinal assessment of segmental motion of the cervical spine following total disc arthroplasty: a comparative analysis of devices
Authors: Colman Matthew W. , Zavras Athan G. , Federico Vincent P. , Nolte Michael T. , Butler Alexander J. , Singh Kern , Phillips Frank M.
Published: April 2022

OBJECTIVE

Total disc arthroplasty (TDA) has been shown to be an effective and safe treatment for cervical degenerative disc disease at short- and midterm follow-up. However, there remains a paucity of literature reporting the differences between individual prosthesis designs with regard to device performance. In this study, the authors evaluated the long-term maintenance of segmental range of motion (ROM) at the operative cervical level across a diverse range of TDA devices.

METHODS

In this study, the authors retrospectively evaluated all consecutive patients who underwent 1- or 2-level cervical TDA between 2005 and 2020 at a single institution. Patients with a minimum of 6 months of follow-up and lateral flexion/extension radiographs preoperatively, 2 months postoperatively, and at final follow-up were included. Radiographic measurements included static segmental lordosis, segmental range of motion (ROM) on flexion/extension, global cervical (C2–7) ROM on flexion/extension, and disc space height. The paired t-test was used to evaluate improvement in radiographic parameters. Subanalysis between devices was performed using one-way ANCOVA. Significance was determined at p < 0.05.

RESULTS

A total of 85 patients (100 discs) were included, with a mean patient age of 46.01 ± 8.82 years and follow-up of 43.56 ± 39.36 months. Implantations included 22 (22.00%) M6-C, 51 (51.00%) Mobi-C, 14 (14.00%) PCM, and 13 (13.00%) ProDisc-C devices. There were no differences in baseline radiographic parameters between groups. At 2 months postoperatively, PCM provided significantly less segmental lordosis (p = 0.037) and segmental ROM (p = 0.039). At final follow-up, segmental ROM with both the PCM and ProDisc-C devices was significantly less than that with the M6-C and Mobi-C devices (p = 0.015). From preoperatively to 2 months postoperatively, PCM implantation led to a significant loss of lordosis (p < 0.001) and segmental ROM (p = 0.005) relative to the other devices. Moreover, a significantly greater decline in segmental ROM from 2 months postoperatively to final follow-up was seen with ProDisc-C, while segmental ROM increased significantly over time with Mobi-C (p = 0.049).

CONCLUSIONS

Analysis by TDA device brand demonstrated that motion preservation differs depending on disc design. Certain devices, including M6-C and Mobi-C, improve ROM on flexion/extension from preoperatively to postoperatively and continue to increase slightly at final follow-up. On the other hand, devices such as PCM and ProDisc-C contributed to greater segmental stiffness, with a gradual decline in ROM seen with ProDisc-C. Further studies are needed to understand how much segmental ROM is ideal after TDA for preservation of physiological cervical kinematics.
Segmental range of motion after cervical total disc arthroplasty at long-term follow-up: a systematic review and meta-analysis
Authors: Zavras Athan G. , Dandu Navya , Nolte Michael T. , Butler Alexander J. , Federico Vincent P. , Sayari Arash J. , Sullivan T. Barrett , Colman Matthew W.
Published: April 2022

OBJECTIVE

As an alternative procedure to anterior cervical discectomy and fusion, total disc arthroplasty (TDA) facilitates direct neural decompression and disc height restoration while also preserving cervical spine kinematics. To date, few studies have reported long-term functional outcomes after TDA. This paper reports the results of a systematic review and meta-analysis that investigated how segmental range of motion (ROM) at the operative level is maintained with long-term follow-up.

METHODS

PubMed and MEDLINE were queried for all published studies pertaining to cervical TDA. The methodology for screening adhered strictly to the PRISMA guidelines. All English-language prospective studies that reported ROM preoperatively, 1 year postoperatively, and/or at long-term follow-up of 5 years or more were included. A meta-analysis was performed using Cochran’s Q and I2 to test data for statistical heterogeneity, in which case a random-effects model was used. The mean differences (MDs) and associated 95% confidence intervals (CIs) were reported.

RESULTS

Of the 12 studies that met the inclusion criteria, 8 reported the long-term outcomes of 944 patients with an average (range) follow-up of 99.86 (60–142) months and were included in the meta-analysis. There was no difference between preoperative segmental ROM and segmental ROM at 1-year follow-up (MD 0.91°, 95% CI −1.25° to 3.07°, p = 0.410). After the exclusion of 1 study from the comparison between preoperative and 1-year ROM owing to significant statistical heterogeneity according to the sensitivity analysis, ROM significantly improved at 1 year postoperatively (MD 1.92°, 95% CI 1.04°–2.79°, p < 0.001). However, at longer-term follow-up, the authors again found no difference with preoperative segmental ROM, and no study was excluded on the basis of the results of further sensitivity analysis (MD −0.22°, 95% CI −1.69° to −1.23°, p = 0.760). In contrast, there was a significant decrease in ROM from 1 year postoperatively to final long-term follow-up (MD −0.77°, 95% CI −1.29° to −0.24°, p = 0.004).

CONCLUSIONS

Segmental ROM was found to initially improve beyond preoperative values for as long as 1 year postoperatively, but then ROM deteriorated back to values consistent with preoperative motion at long-term follow-up. Although additional studies with further longitudinal follow-up are needed, these findings further support the notion that cervical TDA may successfully maintain physiological spinal kinematics over the long term.
Early surgical versus endovascular repair of ruptured blood-blister aneurysm of the internal carotid artery: a single-center 20-year experience
Authors: Eide Per K. , Sorteberg Angelika , Nome Terje , Rønning Pål A. , Sorteberg Wilhelm
Published: April 2022

OBJECTIVE

Early repair of ruptured blood-blister aneurysms (BBAs) of the internal carotid artery (ICA) remains challenging. Although both surgical and endovascular therapies have been established, their relative superiority remains debated. The authors assessed their single-center experience and compared early deconstructive versus reconstructive repair and early reconstructive surgical versus endovascular repair of ruptured BBAs of the ICA.

METHODS

The study included patients who underwent repair of ruptured BBAs of the ICA within 1 week after the ictus during a 20-year period. Multiple variables were recorded, including clinical state, severity of subarachnoid hemorrhage (SAH), characteristics of the BBA, treatment details, complication profile, need for secondary treatment, and clinical outcome.

RESULTS

In total, 27 patients underwent early surgical (n = 16) or endovascular (n = 11) repair of BBAs at a median of 24 hours (range 9–120 hours) after the ictus during the period from September 2000 to June 2021 (20.4 years). Primary deconstructive repair (n = 6) without bypass was accompanied by middle cerebral artery (MCA) territory infarction in 5 of 6 (83%) patients and a high mortality rate (4/6 [67%]). Among the 21 patients who underwent early reconstructive repair, surgery was performed in 11 patients (clipping in 6 and clip-wrapping in 5 patients) and endovascular repair in 10 patients (flow diversion in 7 and stent/stent-assisted coiling in 3 patients). No differences were found in complication profiles or clinical outcomes between the surgical and endovascular groups. The mortality rate was low (2/21 [9.5%]), with 1 fatality in each group.

CONCLUSIONS

From the authors’ experience, both surgical and endovascular approaches permitted reconstructive repair of ruptured BBAs of the ICA, with no modality proving superior. Reconstructive treatment is preferable to ICA sacrifice, and if sacrifice is chosen, it should be accompanied with bypass surgery or delayed to the phase when cerebral vasospasm has resumed. The rare occurrence of this disease calls for prospective multicenter studies to improve treatment and delineate which modality is preferable in individual cases.
Relevansi Sikap Profetik dengan Dimensi Idealisme Pancasila: Sistem Nilai Dalam Menghadapi Tekanan Ekonomi Dan Mental Selama Pandemi Covid-19
Authors: Thohir Muhammad , Za’imuddin Muhammad Hamdan , Fuadina Izza Nur , Fitri Ayu Laila
Published: April 2022

The Indonesian people are facing economic impacts and mental pressure due to the increasingly threatening attacks of the Covid-19 outbreak. However, Indonesia is a religious and nationalist nation, which has a strong value system based on the religious norms and ideology of Pancasila.Therefore, the purpose of this study is to explain, what, why and how to strengthen the prophetic attitudes and idealism dimension of the Pancasila to be built in order to deal with the economic and psychological pressures of the people affected by COVID-19. By using a qualitative approach, the researcher chooses the library research method, namely the study of various sources of literature relevant to the purpose of the study. Literature data obtained were analyzed both textually, contextually and contextually. The results showed that the prophetic attitude and dimensions of Pancasila idealism are a highly relevant, mutually reinforcing value system, especially in facing the threat of the Covid-19 outbreak, both from an economic perspective and mental challenges. The relevance of prophetic attitudes and dimensions of Pancasila idealism here as character strengthening are able to present a values system that can be called as moderative idealism, not right idealism, nor left idealism.
Pola Pembelajaran pada Anak Autis di SLB Negeri 1 Sumbawa
Authors: Kurniawansyah Edy , Fauzan Ahmad , Tamalasari Emi
Published: April 2022

Anak autis merupakan anak yang yang mengalami gannguan pada intraksi sosial, komunikasi, dan perubahan perilaku yang ada pada dirinya. Anak Autis membutuhkan penerimaan, bimbingan dan dukungan ekstra dari orang tua dan lingkungannya untuk tumbuh dan mengembangkan potensi dirinya secara optimal agar dapat hidup mandiri seutuhnya. Penelitian ini bertujuan untuk mengetahui pendidikan pada anak Autis (Studi Kasus di SLB Negeri 1 Sumbawa). Kemudian metode yang digunakan dalam penelitian ini yaitu kualitatif dengan pendekatan deskriptif. Teknik pengumpulan data dengan cara observasi, wawancara dan dokumentasi. Hasil penelitian ini menunjukkan bahwa pola pembelajaran pada anak autis di SLB Negeri 1 Sumbawa terdapat dua model pembelajaran yang diberikan yaitu kelas klasikal dan kelas individual. Sedangkan metode yang digunakan dalam pembelajaran yaitu metode stimulus visual Pembelajaran yang menggunakan alat bantu sebagai media pembelajaran seperti gambar dan poster. Teknik yang di gunakan guru bervariasi mengikuti keadaan peserta didik.Autistic children are children who experience disturbances in social interactions, communication, and changes in their behavior. Autistic children need extra acceptance, guidance and support from parents and their environment to grow and develop their potential optimally in order to live completely independently. This study aims to determine education in children with autism (Case Study in SLB Negeri 1 Sumbawa). Then the method used in this research is qualitative with a descriptive approach. Data collection techniques by means of observation, interviews and documentation. The results of this study indicate that the learning patterns in children with autism in SLB Negeri 1 Sumbawa have two learning models given, namely the classical class and the individual class. While the method used in learning is the visual stimulus method of learning which uses learning tools as learning media such as pictures and posters. The techniques that the teacher uses vary according to the circumstances of the students.
Pendidikan Pembebasan (Studi Pemikiran Paulo Freire dan KH Ahmad Dahlan)
Authors: Salim Hani Muhammad Abdul , Ilham Ilham
Published: April 2022

Pendidikan merupakan salah satu unsur yang penting dalam rangka meningkatkan Sumber Daya Manusia. Sumber Daya manusia itu, sebagai indikator untuk menilai  negara dapat dikategorikan sebagai Negara maju atau sebagai Negara berkembang. Namun, dalam perkembangnya dunia pendidikan berkolaborasi dengan dengan dunia industri, sehingga manajerial disetarakan dengan perusahaan. Kebijakan yang diambil oleh pemerintah tersebut menjadikan pendidikan diorientasikan pada pasar, sehingga melahirkan “robot-robot” manusia dan mahalnya biaya pendidikan. Dalam rangka menanggulangi persoalan tersebut, maka diperlukan konsep pendidikan pembebasan.  Artikel ini, ingin mengkaji pemikiran pendidikan dari Paulo Feire dan KH Ahmad Dahlan sehingga dapat memberikan kontribusi terhadap persoalan tersebut. Hasil dari kajian ini, mendeskripsikan bahwa keduanya menjadikan pendidikan sebagai sarana untuk mengembangkan manusia sehingga mampu bersama dengan lingkungannya melakukan perubahan sosial. Sitem pendidikan yang dilaksanakan dilakukan secara diologis dan sesuai dengan kebutuhan peserta. Pemikiran dan pelaksanaan pendidikan pembebasan Paulo Freire tidak berkembang dengan baik dan autopis. Hal ini, berbeda dengan pemikiran pendidikannya berkembang dengan melahirkan berbagai lembaga pendidikan di Indonesia.Education is an essential element in improving Human Resources. In its development, education collaborates with industrialization, where the management of education is equal to that of companies. This policy makes education market-oriented. This can give birth to human "robots," and the cost of education is expensive. This problem can be faced by designing and the necessary concept of education liberation. This article examined Paulo Freire and KH Ahmad Dahlan's educational thoughts regarding the idea of education liberation as a contribution to educational problems. This research was a qualitative study using a descriptive-critical approach. Methods of data collection using documentation and literature. Methods of data analysis using data reduction, data display, and conclusions. The results of this study described that KH. Ahmad Dahlan and Paulo Freire used education to develop people so that they could make social change. The education system is implemented in a dialogical manner and in accordance with the needs of the participants. Paulo Freire's thinking and application of liberation education were not well developed and atopic. In contrast, Ahmad Dahlan's thought and application of education were developed by creating various educational institutions in Indonesia.