bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of novel high mannose N-glycan isomers undescribed by current multicellular eukaryotic biosynthetic pathways
Authors: Ni Chi-Kung , Liew Chia Yen , Luo Hong-Sheng , Yang Ting-Yi , Hung An-Ti , Magoling Bryan John Abel , Lai Charles Pin-Kuang
Published: August 2022

N-linked glycosylation is one of the most important post-translational modifications of proteins. Current knowledge of multicellular eukaryote N-glycan biosynthesis suggests high mannose N-glycans are generated in the endoplasmic reticulum and Golgi apparatus through conserved biosynthetic pathways. As a part of post-translational modifications, lipid dolichol-phosphate linked oligosaccharide Glc3Man9GlcNAc2 is transferred to proteins, and glucoses and mannose are sequentially removed by various ER- and Golgi-localized glucosidases and -1,2-mannosidases. According to reported biosynthetic pathways, four Man7GlcNAc2 isomers, three Man6GlcNAc2 isomers, and one Man5GlcNAc2 isomer are generated during this process. In this study, we applied our latest mass spectrometry method, logically derived sequence tandem mass spectrometry (LODES/MSn) to re-examine high mannose N-glycans extracted from various multicellular eukaryotes. LODES/MSn identified many high mannose N-glycan isomers previously unreported in plantae, animalia, cancer cells, and fungi. Importantly, their synthesis is yet described by known biosynthetic pathways, thereby suggesting additional and unidentified pathways for these N-glycans isomers in multicellular eukaryotic cells.
CHẾ TẠO VÀ TÍNH CHẤT CỦA VẬT LIỆU TỔ HỢP GRAPHENE – ỐNG NANO CÁCBON – HẠT NANO VÀNG
Authors: Phan Văn Cường , Phan Nguyễn Đức Dược , Cao Thị Thanh , Nguyễn Khánh Như , Lê Thị Quỳnh Xuân , Phạm Văn Trình , Đào Nguyên Thuận , Bùi Thị Phương Thảo , Phạm Đức Thắng , Nguyễn Văn Chúc
Published: August 2022

Trong công trình này, màng tổ hợp của vật liệu graphene (Gr) – ống nano cácbon hai tường (DWCNT) và hạt nano kim loại vàng (AuNPs) (DWCNT-AuNPs-Gr) đã được chế tạo bằng phương pháp lắng đọng pha hơi nhiệt hóa học (CVD). Hình thái học bề mặt và các tính chất điện, điện hóa của vật liệu tổ hợp đã được khảo sát thông qua kính hiển vi điện tử quét phát xạ trường, phổ Raman, điện trở bốn mũi dò và kỹ thuật quét thế vòng (CV). Với nồng độ DWCNTs 0,3 g/L và tốc độ quay phủ 4000 vòng/phút, vật liệu DWCNTs-AuNPs-Gr có điện trở bề mặt giảm 2,3 lần so với màng Gr và đạt khoảng 549 W/sq; dòng đỉnh đáp ứng trong dung dịch 2 mM K3[Fe(CN)6]/K4[Fe(CN)6] trong 0,1 M PBS đạt 15,79 µA tại 50 mV/s, cao gấp 1,48 lần so với điện cực biến tính màng Gr và gấp 2,57 lần so với điện cực trần. Vật liệu DWCNTs-AuNPs-Gr có tiềm năng ứng dụng trong cảm biến điện hóa để phát hiện các phần tử sinh học khác nhau.
Synthesis and characterization of pH-sensitive glucomannan-poly(acrylic acid) hydrogels for 5-aminosalicylic acid controlled delivery systems
Authors: Le Lam Son , Le Thuy Trang , Tran Thi Van Thi , Nguyen Vinh Phu , Nguyen Quang Man , Le Trung Hieu
Published: August 2022

In this study, glucomannan-poly(acrylic acid) hydrogels were synthesized under different conditions. The hydrogels consist of glucomannan and acrylic acid and are crosslinked by N,N-methylene-bis-(acrylamide). The structure and morphology of the hydrogels were investigated by using Fourier-transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM). The swelling ratio, biodegradation and pH-sensitive properties, relationship between hydrogel swelling rate and 5-ASA adsorption-desorption capacity, influence of medium pH on 5-ASA desorption, and 5-ASA adsorption kinetics were studied. The swelling ratio of the synthesized hydrogel samples is 16.70–56.21 times. This ratio is low in the pH 1.0 media and increases significantly in the pH 7,4 media. The hydrogels are biodegradable in the presence of cellulase (400 U·mg–1) in a pH 7.4 phosphate buffer at 37 °C (69.8% after ten days; the cellulase concentration 1.5 g·L­–1). The hydrogels exhibit high adsorption and desorption capacities for 5-ASA. The adsorption kinetics follows the pseudo-first-order model. These hydrogels can be applied to smart drug delivery systems.
Improving Inflation Forecasts Using Robust Measures
Authors: Verbrugge Randal J. , Zaman Saeed
Published: August 2022

Both theory and extant empirical evidence suggest that the cross-sectional asymmetry across disaggregated price indexes might be useful in the forecasting of aggregate inflation. Trimmed-mean inflation estimators have been shown to be useful devices for forecasting headline PCE inflation. But does this stem from their ability to signal the underlying trend, or does it mainly come from their implicit signaling of asymmetry (when included alongside headline PCE)? We address this question by augmenting a “hard to beat” benchmark inflation forecasting model of headline PCE price inflation with robust measures of trimmed-mean estimators of inflation (median PCE and trimmed-mean PCE) and robust measures of the cross-sectional asymmetry (Bowley skewness; Kelly skewness) computed using the 180+ components of the PCE price index. We also construct new trimmed-mean measures of goods and services PCE inflation and their accompanying robust skewness. Our results indicate significant gains in the point and density accuracy of PCE inflation forecasts over medium- and longer-term horizons, up through and including the COVID-19 pandemic. We find that improvements in accuracy stem mainly from the trend information implicit in trimmed-mean estimators, but that skewness is also useful. Median PCE slightly outperforms trimmed-mean PCE; both outperform core PCE. For point forecasts, Kelly skewness is preferred; but for estimating stochastic volatility, Bowley skewness is preferred. An examination of goods and services PCE inflation provides similar inference.
Beta talasemi hastalarında immatür granülosit sayısı kemik iliği aktivasyonunu değerlendirmede pratik bir belirteç olabilir mi?
Authors: İNCE Banu , KARAHAN Feryal , AKDENİZ Aydan , ÜNAL Selma
Published: August 2022

Amaç: Çalışmamızda çocuk ve erişkin beta talasemi major ve intermedia hastalarımızın immatür granülosit ve immatür granülosit yüzdelerinin kemik iliği aktivasyonlarını değerlendirmede pratik bir belirteç olarak kullanılıp kullanılamayacağını araştırmayı amaçladık. Yöntem: Ocak 2017-Aralık 2021 tarihleri arasında Mersin Üniversitesi Tıp Fakültesi Çocuk ve Erişkin Hematoloji kliniğinde takipli 38 Beta talasemi major ve 12 Beta talasemi intermedia hastasının yaş, hemoglobin (gr/dl), hematokrit, beyaz küre sayısı (x103/µL), trombosit değeri (x103/µL), immatür granülosit sayısı ( x103/µL) , immatür granülosit yüzdesi (%), ferritin değeri (ng/mL), şelasyon durumu, transfüzyon sıklığı ve düzeni, son bir yıldaki ortalama hemoglobin düzeyi gibi parametreleri incelendi. Düzenli transfüzyon alan ve almayan hastalar immatür granülosit sayısı, yüzdesi ve diğer parametreler açısından karşılaştırıldı. Bulgular: Hastalar çocuk ve erişkin olarak gruplandığında; çocuk hastalarda son bir yıldaki hemoglobin düzeyi daha yüksek iken erişkinlerde beyaz kan hücresi, immatür granülosit ve trombosit sayısının anlamlı olarak daha yüksek olduğu görüldü (p<0.05). Çocuk hastaların daha düzenli transfüzyon aldığı gözlendi. Düzensiz transfüzyon alan hastalarda son bir yıldaki ortalama hemoglobin düzeyinin anlamlı oranda daha düşük ancak immatür granülosit düzeyi, trombosit ve beyaz küre sayısının daha yüksek olduğu görüldü (p<0.05). Son bir yıldaki ortalama hemoglobin düzeyi arttıkça ortalama immatür granülosit sayısı ve yüzdesinin azaldığı saptandı. Sonuç: Çalışmamızda immatür granülosit sayısı ve yüzdesi, total beyaz küre ve trombosit sayısının düzensiz transfüzyon alan hastalarda istatistiksel açıdan anlamlı olacak şekilde yüksek olması ve son bir yıldaki ortalama hemoglobin düzeyi azaldıkça immatür granülosit ve immatür granülosit yüzdesinin artması bu hastalarda kemik iliğindeki hematopoezin aktif olduğunu düşündürdü. Bu nedenle beta talasemili hastalarda inflamatuvar aktivitenin derecesini ve transfüzyon etkinliğini değerlendirmede hemen her merkezde bakılabilen immatür granülosit ve immatür granülosit yüzde parametrelerinin kullanılabileceğini düşünmekteyiz.
Impact of social media on student life
Authors: Bhumika Tuli , Jyoti  , Neha Gautam , Santosh Kumar
Published: August 2022

The Internet has changed everyone's life. Social networks may have only been initiated with the help of the Internet. Today's generation is using the internet, which means social media like Snap-chat, Twitter, Facebook, etc., is increasing. Hence, the purpose of this paper is to understand the positive and negative outcomes of social media. In addition, this paper discusses the current situation, the previous situation, and the situation where people do not have social networks. Finally, the influence of social networks on different stages of a person's life is described.
Concentration of lycopene from watermelon juice using cross-flow filtration
assisted with diafiltration
Authors: Nguyen L.T. , Nguyen T.K.T. , Mai H.C.
Published: August 2022

Watermelon is a well-known and high-consumed fruit in Vietnam, considered a rich
source of bioactive compounds, especially lycopene. The cross-flow filtration coupled
with diafiltration was processed to obtain the concentrated lycopene. The microfiltration
process was conducted at a temperature of 50-60oC by using a ceramic α-Al2O3 membrane
with a pore size of 0.08 µm. Permeate was removed while the collected retentate was
fractionated into two parts for further experiments. The first part of the retentate was
directly centrifuged. The effect of centrifugation time (2, 5, and 8 mins) and speed (1000,
3000, and 5000 rpm) on lycopene content were evaluated. The other part of the retentate
was purified by the diafiltration process. The ratio of retentate: water was varied from
1:0.5 to 1:2 (w/w) to determine its influence on the lycopene content. The results showed
that the suitable transmembrane pressure was selected at 5 bars. The membrane fouling
phenomena was also observed by a rapid decrease in permeate flux in 40 min, followed by
a gradual reduction. The suitable condition of centrifugation was processed at 3000 rpm in
5 mins. The centrifuged retentate in 60 mins of microfiltration contained a lycopene
content of 146.63±2.76 µg/mL. The retentate: water ratio of 1:0.5 was noted as an
effective ratio to purify the lycopene content, achieving 273.42±4.56 µg/mL. The
physicochemical properties of the raw watermelon juice and retentate indicated a positive
result from the retentate with enhanced total solid content, lycopene concentration as well
as purity.
External Ear Reconstruction By Antia-Buch Chondro-Cutaneous Advancement Flap in a Case of Human Bite – A Case Report
Authors: Gulreez Rasheeqa , Abdelhamid Mokhtar Mahmoud , Louri Nayef Abdulrahman
Published: August 2022

Reconstruction of the external ear is a challenging problem encountered by plastic surgeons. Causes of external ear deformities can be of various etiologies (human bites, animal bites, fights, burns, infections, accidents, or even sports injuries). Full-thickness defects, which cannot be treated by approximating the wound edges, show good results with Antia-Buch’s chondro-cutaneous flaps. A 34-year-old male presented with a history of human bite to his right external ear. The patient had brought the amputated part with him. There was complete amputation of the superior part of the helix with exposed cartilage with a 2 cm defect on examination. The amputated part was an unhealthy crushedavulsed tissue. The patient underwent debridement and washout. Reconstruction of the external ear was done by Antia-Buch helical advancement flap designed over the posterior skin. Post-operatively, the external ear reconstruction yielded good cosmetic results. Animal or human bite defects used to be left open for fear of severe infections, and closure was planned later, but this can be complicated by fibrosis and can result in a change in the shape of the external ear. Primary repair using an Antia-Buch flap and appropriate antibiotic treatment shortens the hospital stay and dressing changes and improves the cosmetic outcome. Keywords: Amputation, Cartilage, External ear, Fibrosis, Human Bite, Reconstructive Surgical Procedures
A Proposed Program for Protecting Youth from Intellectual Deviation in the Cooperation Council for the Arab States of the Gulf
Authors:   College of Education Umm Al-Qura University Kingdom of Saudi Arabia, Maddah Samia , Fateel Musa ,   College of Education Umm Al-Qura University Kingdom of Saudi Arabia, Maddah Hani ,   College of Education Umm Al-Qura University Kingdom of Saudi Arabia, AlKarashi Muhammad ,   College of Education Umm Al-Qura University Kingdom of Saudi Arabia
Published: August 2022

This study aims to identify the measures taken by the countries of the Gulf Cooperation Council in the face of intellectual deviation among youth. The target is to reveal the causes of intellectual deviation among young people in the countries of the Gulf Cooperation Council (GCC) and to develop a proposed program to immunize the youth from intellectual deviation in the GCC countries. The researcher applies the descriptive and analytical method in this study, and the study tool used is the questionnaire. The study population consists of all young citizens in the countries of the Gulf Cooperation Council, and the sample is stratified random. This study reaches a set of results, including the following: Economic measures are the most common measures taken by GCC countries to confront the intellectual deviation among young people. Then come the institutional measures, then the social measures. The media work to criticize and analyze the problem of intellectual deviation and thus contribute to strengthening cohesion within society. The upbringing patterns used by contemporary Gulf families contribute to immunizing their children from intellectual deviation. Among the recommendations the study makes are the following: The concerted efforts of state agencies and community institutions in the GCC countries, with the cooperation of individuals and families, to discover early manifestations of intellectual deviation Adopting a promising new vision for sustainable development, and engaging youth in its implementation in the GCC countries. Implementing strategic plans to immunize youth from delinquency, with a community partnership
A Survey on the Number of Drug Addicts in the Arab Countries and the Centers of Treatment and After-Care
Authors:   College of Criminology  Naif Arab University for Security Sciences    Kingdom of Saudi Arabia, Alkurdi Khaled
Published: August 2022

This study aims to identify the numbers of drug users in several Arab countries during the first, second, third, and fourth quarters of 2016, 2017, and 2018, according to available official statistics, and to learn the types and quantities of drugs and psychotropic substances seized in Arab countries according to the official statistics available during the first quarter of 2019. The study also seeks to identify the number of users, distributed according to the type of substance abuse during the first quarter of 2019, according to available official statistics. It also seeks to find out the most important treatment and aftercare centers for addicts in some Arab countries. The researcher uses the descriptive-survey method for statistics of some Arab countries on drug abuse and addiction. This study describes cases of abuse and addiction between 2016 and 2019. It reaches a set of results, one of which is that the number of drug users in 2016 reached 46,942 drug users, in 2017 it reached 126,216 drug users, during 2018 it reached 111,351 users, and the number of drug users during the first quarter of 2019 was 30,897 males and 248 females. Among the recommendations the study makes are the following: To prepare periodic Arab reports on the prevalence of drug abuse within Arab countries and the exchange of data and information between those countries To improve mechanisms for obtaining information on drug abuse in the Arab countries • To strengthen cooperation between Arab countries in the field of drug control
Pengembangan E-LKPD Berbasis Learning Cycle 5E Materi Sistem Pencernaan untuk Meningkatkan Ketrampilan Proses Terintegrasi Peserta Didik Kelas XI SMA
Authors: Nurulia Gita Saula , Qomariyah Nur
Published: August 2022

Inovasi dalam pembelajaran penting dilakukan dalam mencapai tujuan belajar. Inovasi yang dapat dilakukan adalah mengembangkan atau menyempurnakan bahan ajar. Salah satunya e-LKPD. e-LKPD sangat membantu dalam pembelajaran terutama pada situasi pandemi Covid-19, semua kegiatan pembelajaran menjadi daring. e-LKPD juga dapat melatih keterampilan proses terintegrasi peserta didik. Meningkatkan keterampilan proses terintegrasi dibutuhkan pendekatan konstruktivis menggunakan Learning Cycle 5E. Penelitian ini bertujuan untuk menunjang pembelajaran pada materi sistem pencernaan sehingga keterampilan proses terintegrasi dapat ditingkatkan dengan memenuhi syarat secara teoritis. Penelitian termasuk jenis penelitian pengembangan mengunakan model pengembangan 4-D (Define, Design, Develop, dan Disseminate). Kelayakan e-LKPD secara teoritis didapatkan dari hasil validasi. Kualifikasi e-LKPD secara teoritis diperoleh berdasarkan hasil validasi. Validasi dilakukan oleh tiga validator, dua dosen ahli materi dan media pembelajaran, serta seorang guru Biologi SMA. Penilaian validasi memiliki tiga aspek yang diamati yaitu isi, penyajian dan bahasa. Hasil penelitian ini menunjukkan bahwa e-LKPD secara teoritis memenuhi syarat dengan persentase skor validasi sebesar 94,3% yang menandakan kategori sangat valid. Disimpulkan bahwa e-LKPD berbasis Learning Cycle 5e pada materi sistem pencernaan yang dikembangkan layak digunakan untuk meningkatkan keterampilan proses terintegrasi peserta didik kelas XI SMA. Penelitian lanjutan dalam pengembangan e-LKPD secara langsung kepada peserta didik perlu dilakukan.

Kata Kunci: e-LKPD, Learning Cycle 5e, keterampilan proses terintegrasi, sistem pencernaan.
Development of Pterintifier (Pteridophyta Identifier) Based on as a Learning Source and to Train Digital Literacy for 10th Grade in Senior High School
Authors: Faizah Afifah Al , Wisanti Wisanti
Published: August 2022

Digital literacy is a student's ability that must master in the 21st century. One of the efforts to practice digital literacy is to use social media as a learning resource. Pterintifier (Pteridophyta Identifier) ​​uses Instagram as a learning resource with the account name Pterintifier.id, presenting information on ferns. The purpose of this study is to produce a Pterintifier as a learning resource for the diversity of ferns to practice digital literacy that is feasible theoretically, empirically, and effectively. This study uses a 4D model without the stage of being disseminated. The pterintifier eligibility parameters are based on validation results from 3 validator (botanist, education expert, biology teacher), student responses, and user effectiveness. The research instruments are validation assessment instruments, student response questionnaires, and the point of the Pterintifier. The validation assessment includes aspects of content, presentation, learning resources, and digital literacy, while the response questionnaire consists of 20 statement items related to aspects of concept presentation and physical presentation. The data analyzed by descriptively quantitatively. The results showed that the validity of the Pterintifier was 3,69 (very valid). The effectiveness of Pterintifier to train digital literacy based on student success and student responses. Based on the success of using the Pterintifier, the results were 98,3 (very good), and positive student responses were 98,3 (very good). Thus, this development research resulted in the Pterintifier as a theoretical, empirical, and effective learning resource as learning resource for fern diversity to practice digital literacy.

Keywords: Instagram, learning souce, digital literacy, fern diversity.
Pengembangan E-Modul Berbasis QR-Code untuk Melatihkankemampuan Literasi Digital Siswa pada Materi Perubahan lingkungan
Authors: Pratiwi Maulidatul Kurnia , Indana Sifak
Published: August 2022

Menanggulangi kesulitan siswa dalam melakukan pembelajaran jarak jauh dapat dilakukan denganmemilih media pembelajaran yang tepat dengan memperhatikan kondisi dan kemajuan teknologi. Sehingga, dapat mendorong kemampuan literasi untuk menerima dan menyampaikan informasi. Tujuanpenelitian ini yaitu menghasilkan e-modul berbasis QR-code untuk melatihkan kemampuan literasi digitalsiswa pada materi perubahan lingkungan yang valid dan efektif. Metode yang digunakan adalah metode4D (Define, Design, Develop and Disseminate) tahap Disseminate tidak dilakukan. Validitas e-modulQR-Code diperoleh dari validasi 2 pakar yaitu ahli biologi, ahli pendidikan dan salah satu guru biologiSMA Labschool Unesa. Keefektifan e-modul QR-Code diperoleh dari hasil pretest dan posttest dengannilai perhitungan N-gain serta diperoleh dari angket respons 15 siswa heterogen kelas X MIPAI SMALabschool Unesa. Data validitas dan keefektifan dianalisis secara deskriptif kuantitatif. Hasil analisismenunjukkan e-modul QR-Code yang dikembangkan mendapat persentase validitas 93,56%kategorisangat valid. Keefektifan e-modul QR-Code yang dikembangkan dikategorikan efektif terlihatpeningkatan nilai pretest ke nilai posttest dengan ketuntasan posttest sebesar 100%. Serta, dari hasilangket respons siswa yang merespon positif dengan persentase keseluruhan 91, 22% kategori sangat baik. Berdasarkan penelitian tersebut, e-modul berbasis QR-Code untuk melatihkan kemampuan literasi digitalsiswa pada materi perubahan lingkungan dikatakan valid dan efektif untuk diterapkan pada kegiatanpembelajaran. Sehingga siswa dapat memiliki kemampuan literasi digital yang tinggi untuk meningkatkanhasil belajar. Kata Kunci: e-modul QR-code, literasi digital, perubahan lingkungan
Stem-nesting Hymenoptera in Irish farmland: empirical evaluation of artificial trap nests as tools for fundamental research and pollinator conservation
Authors: Hodge Simon , Bottero Irene , Dean Robin , Maher Stephanie , Stout Jane
Published: August 2022

Insect pollinators are suffering global declines, necessitating the evaluation and development of methods for long-term monitoring and applied field research. Accordingly, this study evaluated the use of trap nests (“bee hotels”) as tools for investigating the ecology of cavity nesting Hymenoptera within Irish agricultural landscapes. Three trap nests consisting of 110 mm diameter plastic pipe containing 100 cardboard nest tubes of varying diameter were placed at eight apple orchards and eight oilseed rape sites and left in the field for five months. Sealed nest tubes occurred at 15 of the 16 sites, and in 77% of the 48 nests. However, only 7% of the 4800 individual nest tubes were sealed, and only 4% produced cavity-nesting Hymenoptera. Three cavity nesting bee species (Hylaeus communis, Osmia bicornis, Megachile versicolor) and two solitary wasp species (Ancistrocerus trifasciatus, A. parietinus) emerged from nest tubes. There were significant differences among species in terms of emergence date and the diameter of nest tubes from which they emerged, the latter allowing the calculation of niche width and niche overlap, and informing choice of tube size in future studies/conservation efforts. Trap nests, therefore, offer a valuable tool for fundamental ecological research and a model system for investigating interactions between stem-nesting species within their wider ecological networks. The ability of trap nests to actually increase farmland pollinator abundance and diversity as part of agri-environment schemes requires additional investigation. However, used in sufficient numbers, these trap nests provide valuable biogeographical data for cavity nesting Hymenoptera and offer a viable means for long term monitoring of these species in Irish farmland.
The Development of an Ebook Integrated with Learning Management System to Improve Student's Metacognition Ability
Authors: Mardin Sutrisnawati , Ramadhan Achmad , Ismail Masrianih
Published: August 2022

This study aims to develop an ebook that is integrated with a Learning Management System (LMS) to improve students' metacognition skills. The research uses the ADDIE development model (Assumption, Design, Development, Implementation, Evaluation). The research data were obtained from 40 students who filled out the questionnaire and took the pretest and posttest. The effectiveness of the ebook on improving metacognitive skills used N-Gain analysis and to determine the difference between the experimental and control classes, a T-test was performed, using One Group Pretest and Post-test Design. The results showed that ebook development was very good. The development of ebooks integrated with LMS can significantly improve students' metacognitive abilities. Thus, this study recommends that lecturers use ebooks that are integrated into the learning management system so that learning can run effectively to improve students' metacognitive abilities.
Pengambangan Perangkat Pembelajaran Berbasis Pendekatan Saintifik Materi Pembelahan Sel Kelas XII SMA
Authors: Lodang Hamka , Baharuddin Rahmat , Kurnia Nani , Saenab Sitti
Published: August 2022

This research and development aims to produce learning tools in the form of handouts and Student Worksheets (LKPD) based on a scientific approach to cell division material for class XII SMA that are valid and practical, using the ADDIE development model which consists of five stages, namely analysis (analyze), design, development, implementation, and evaluation. The research location is at SMAN 1 Wonomulyo, Polewali Mandar, West Sulawesi. The research subjects were Biology teachers and class XII students of SMA 1 Wonomulyo. The assessment of the validity of the handouts and worksheets was carried out by two expert validators using a validation sheet. The practicality of the handouts and LKPD were assessed based on the responses of two teachers and 31 students using a questionnaire. The results showed that the average score of the total validity of the handouts and LKPD were 3.50 and 3.53, respectively, with a very valid category. The value of the practicality of the handouts based on the responses of teachers and students are 95.00% and 91.45%, respectively, in the very practical category. The practical value of the LKPD based on the responses of teachers and students is 93.75% and 91.13%, respectively, in the very practical category. It was concluded that the handouts and worksheets based on the scientific approach that were developed were stated to be very valid and very practical.
The relationship between positive thinking, social support, and students’ psychological well-being during online learning
Authors: Munandar Haris , Herman Herman , Putra Dimas Adi , Nilam Nilam
Published: August 2022

This research aimed to see the relationship between positive thinking and social support with psychological well-being in UMPR PGSD students during online learning.  The research was conducted in Muhammadiyah University of Palangkaraya campus area. The subjects were UMPR PGSD students who had taken the 4th semester of college minimal or above in this research.  The sampling technique used purposive sampling with criteria. This research used quantitative method by correlational study approach. Data analysis method used correlational analysis technique or regression analysis in this research. This research result was found that there were significant relationship between positive thinking and social support with psychological well-being in UMPR PGSD students during online learning with correlation coefficient (R) of 0.707 which was converted to F Regression of 28.407 with significance level of 0.000 (p< 0.05). The conclusion of the research was that the higher positive thinking and social support obtained students, the higher psychological well-being on students will be followed, n the other hand, the lower the high of positive thinking and social support obtained students, the lower the psychological well-being on students will be followed.
The Impression That I Get: The Influence of Brand Equity on Purchase Decisions
Authors: Musa Muhammad Ichwan , Sareong Wira Yunita , Haeruddin M. Ikhwan Maulana , Haeruddin Muhammad Ilham Wardhana , Burhanuddin Burhanuddin
Published: August 2022

This study aims to determine the effect of brand equity on purchasing decisions in which there are four variables: (1) the effect of brand awareness on purchasing decisions at PT. Sarana Sinar Sulawesi (SSS) in South Sulawesi Province. (2) The influence of brand association of purchasing decisions at PT. Sarana Sinar Sulawesi in South Sulawesi Province. (3) The effect of perceived quality on purchasing decisions at PT. Sarana Sinar Sulawesi (SSS) in South Sulawesi Province. The population in this study were all consumers of PT. Sarana Sinar Sulawesi in 2017, while the sample taken was 100 respondents. The data analysis technique used was multiple regression analysis using two statistical method tests, namely partial test (t test) and simultaneous test (f test). The results of this study indicate that multiple regression analysis, the regression equation Y = 13.342 + 0.100X1 + 0.295X2 + 0.015X3 + 0.198X4 + 4.202 is obtained. Based on statistical data analysis, all variables are valid and reliable. In the classical assumption test, it is stated that all indicators are normally distributed and there is a significant linear relationship between each independent variable and the dependent variable. The coefficient of determination test results shows that 74% of purchasing decisions at PT. Sarana Sinar Sulawesi is influenced by the variables examined in this study.
Utilization Of Imagination-Based Plasticine Media In Improving Fine Motor Skills In Kindergarten
Authors: Andayani Faridah , Wijayanti Catur Nur
Published: August 2022

The purpose of the study was to determine efforts to improve students' fine motor skills through plasticine play activities. The research subjects of the students of TK Dharma Wanita Persatuan Pangkemiri Sidoarjo East Java, totaling 15 people. The focus of the study was fine motor and plasticine play activities. This study used a classroom action research approach with descriptive data analysis to display data using student observation sheets. The results of data analysis showed that plasticine play activities were able to improve children's fine motor skills. The improvement appears in the ability to form eye and hand coordination and the smoothness of the child's hands. The analysis data of the results showed an increase from cycle I with the completeness of learning outcomes of 23% with an average score of 1.80 to 40% of the totality of learning outcomes and the average score of students of 2.47 in cycle II and continued to increase in cycle III with the acquisition of completeness of learning outcomes reaching a maximum of 100% with an average score of students of 3.27.
An Analysis of Phrases in Technology Brands Slogan and its Contribution in Teaching English Grammar
Authors: Rizal Ifan Nur , Sumardiyani Listyaning , Lestari Maria Yosephine Widarti
Published: August 2022

A phrase is a group of words that serves as a unit of a sentence. There are several types of phrases namely noun phrase, verb phrase, adjective phrase, adverb phrase, and prepositional phrase. A phrase used in an advertisements and promotional activities such slogans. Every commercial product makes a slogan to attract the attention of target market. This study is a content analysis which aimed at analyzing kind of phrases in syntax categories that found in English technology brand slogans and its contribution in teaching English grammar. The method used in this study was qualitative descriptive to investigate and describe kind of phrase in 40 technology brand slogans and clarify the contribution of the analysis to teaching English grammar. In collecting the data, researcher used note taking. The result shown that researcher find some phrases form. The analysis was recommended by the researcher as a teaching media since its accordance with the English teaching syllable.
Physicochemical Characteristics of Catfish (Clarias sp) Sausage with Addition of Moringa Leaf Flour (Moringa oleifera)
Authors: Rahayu Septiani Dwi , Dwi Ujianti Rizky Muliani , Nurdyansyah Fafa
Published: August 2022

Sausage is a processed food product that is generally made of meat, fat, filler, water, binder and salt. Catfish is a source of animal protein that has advantages compared to other animal products, namely catfish which is rich in lysine, and leucine. Moringa leaf flour is Moringa leaves that are given drying, milling treatment to facilitate processing into various food products and as a fortification material with high nutrition. This study aims to determine the effect of differences in concentration of catfish: tapioca flour with the addition of Moringa leaf flour on the physicochemical properties of catfish sausage. The results obtained in the study that the difference in the concentration of catfish: tapioca flour and the addition of Moringa leaf flour affect the analysis of water content 58%; fat content 13%; ash content 1.85%; protein content 18.09%; color parameter L* 47,26-66,48; color parameter a* (-4.43)-5.40; color parameter b* 14.25-26.71.
MϕA-h-Convexity and Hermite-Hadamard Type Inequalities
Authors: Varošanec Sanja
Published: August 2022

We investigate a family of MϕA-h-convex functions, give some properties of it and several inequalities which are counterparts to the classical inequalities such as the Jensen inequality and the Schur inequality. We give the weighted Hermite-Hadamard inequalities for an MϕA-h-convex function and several estimations for the product of two functions.
Formation of self-control skills in students in the concept of linguistic education
Authors: Bystray Elena B. , Belova Larisa A. , Slabysheva Alevtina V. , Orlova Irina A. , Shtykova Tatiana V.
Published: August 2022

The article is devoted to the study of the problem of the formation of self-control skills in students in the study of a foreign language. The main research methods are the analysis of scientific literature on the problem in the works of domestic and foreign scientists, regulatory and legislative acts of the Russian Federation on higher professional education, as well as diagnostic techniques, including observation, questioning, testing and data processing methods. To solve the problem of developing self-control skills, a pedagogical experiment was carried out. The analysis of the results of the pedagogical experiment confirmed that the development of self-control mechanisms in students studying a foreign language is possible when designing the learning process and using educational strategies.
Examination of the linguocultural characteristics of english based on the analysis of american situational comedies
Authors: Sokolova Natalia Leonidovna , Sergeeva Marina Georgiyevna
Published: August 2022

The article is devoted to the problem of studying the linguocultural characteristics of English based on the analysis of American situational comedies. The study highlights the role of humor and understanding of the cultural figures, necessary for the most effective English language learning. Summing up the results of the research, situational comedy (sitcom) is the most convenient material for studying the linguocultural characteristics of English, due to the abundance of various linguocultural markers and lexical units. The study aims at improving students’ language proficiency by studying the linguocultural characteristics of English based on the analysis of American situational comedies. The results of the study allow concluding that studying the linguocultural characteristics of English based on the analysis of American situational comedies leads to the improvement of students' language proficiency.
National images of the world: verbal and v isual components of the linguistic consciousness of the chinese and russians (on the example of the concept “holiday”)
Authors: Haitong Pei , Chulkina Nina Leonidovna
Published: August 2022

The purpose of the study is to analyze the verbal and visual components of the linguistic consciousness of the Chinese and Russians as components of the national image of the world. The study discusses various points of view on the concept “national image of the world”, and points to certain criteria for defining it. Various interpretations of the concept of human linguistic consciousness in modern linguistics are considered. The method of a drawing experiment was used. At the first stage of the experiment, students were asked to draw the first things that come to mind as a reaction to words and phrases that were obtained as reactions to a HOLIDAY stimulus at the stage of a previously conducted associative experiment. At the second stage, these drawings were shown to new respondents collected. They received the following task: to name the first five words that arise in the mind when looking at this picture. The results of the study confirmed the hypothesis that representatives of different nationalities have similarities in the main thematic groups of associates, but the ratio of these groups is different, which leads to a difference in conceptual fields.
Fixed point theorems of maps satisfying generalized condition (B) in ordered partial metric spaces
Authors: Hashim Amal M.
Published: August 2022

The main purpose of this paper is to introduce and prove some fixed point (F.P) theorems by using a generalized condition (B) in ordered partial metric space. Our results improve and unify a multitude of (F.P) theorems and generalize some recent results in ordered partial metric space
Random Fractional Laplace Transform for Solving Random Time-Fractional Heat Equation in an Infinite Medium
Authors: Khudair Ayad R.
Published: August 2022

The random Laplace and Fourier transforms are very important tools to solve random heat problems. Unfortunately, it is difficult to use these random integral transforms for solving the fractional random heat problems, where the mean square conformable fractional derivative is used to express for the time fractional derivative. Therefore, this work adopts the extension of the random Laplace transform into random fractional Laplace transform in order to solve this kind of heat problems. The stochastic process solution of the fractional random heat in an infinite medium is investigated by using random fractional Laplace transform together with random Fourier transform. The mean and the standard diffusion of the stochastic process solution is computed for different value of fractional order. When α = 1, the results show agree with the available results in the references context.
System modernization of the Union state industrial base
Authors: Turko V. , Arzhaev F.
Published: August 2022

The necessity of having high-quality tools for the balanced development of the diversified complex of the Union State is substantiated. Based on existing developments, a working model of economic planning has been formed, supplemented with modern mathematical tools that have proven themselves in the recent past and can be used today with great efficiency.
Involvement of the intestinal microbiome in the tumor process of the gastrointestinal tract
Authors: Kuznetsov O. , Tsyrkunov V.
Published: August 2022

The article assesses the degree of participation of the microbiome in the development of the pre-tumor process of the gastrointestinal tract. The necessity of studying the pathology of the gastrointestinal tract at the genetic level in relation to the persistence of microorganisms that affect the expression of human genes is shown: their proteins and metabolites interact with the genome, modifying it. The role of opportunistic microflora in the regulation of the immune response in patients with cancer and changes in microbiocenosis in lesions of the large intestine, liver and pancreas, as well as its significance in carcinogenesis are presented. The need for further studies of the mechanisms of development of the tumor process of the gastrointestinal tract and determination of the relationship between the microbiome, the human immune system and carcinogenesis is emphasized.
PENGGUNAAN BAITED FADs SEBAGAI ALAT BANTU PEMIKAT DAN PENGUMPUL IKAN PADA MINI PURSE SEINE
Authors: Laoda Aryadiansyah Dwi Putra A , Zulkarnain  , Komarudin Didin , Sondita Muhammad Fedi Alfiadi
Published: August 2022

Nelayan Tenau di Kupang, Provinsi Nusa Tenggara Timur melakukan kegiatan penangkapan ikan pelagis dengan mini purse seine yang dilakukan pada malam hari menggunakan atraktor cahaya lampu tanpa atraktor rumpon. Lama waktu tunggu dalam proses pengumpulan ikan dengan cahaya lampu menyebabkan operasi penangkapan ikan tidak efektif dan jumlah ikan yang berkumpul di bawah sinar lampu tidak banyak. Penelitian ini mencoba menggunakan kombinasi atraktor rumpon dan umpan atau disebut juga dengan atraktor rumpon berumpan (baited FADs) sebagai perlakuan dalam penelitian. Tujuan penelitian ini adalah menentukan komposisi hasil tangkapan, menentukan pengaruh penggunaan baited FADs dibandingkan dengan kontrol terhadap hasil tangkapan dan jumlah hauling serta menentukan produktivitasnya. Penelitian ini menggunakan metode eksperimental fishing dengan 20 trip sebagai ulangan penelitian. Hasil penelitian menunjukkan bahwa pada mini purse seine perlakuan, terlihat ikan yang tertangkap lebih dari satu jenis per trip dibandingkan dengan mini purse seine kontrol. Hal ini diduga reaksi dari umpan tersebut menyebabkan ikan-ikan berkumpul pada baited FADs. Penggunaan baited FADs telah memberikan pengaruh yang nyata terhadap total berat hasil tangkapan (Asymp. Sig. (2-tailed) < 0,05) dan total hauling/trip (Asymp. Sig. (2-tailed) < 0,05). Persentase kenaikan produktivitas mini purse seine perlakuan terhadap kontrol sebesar 109,3% dan rata-rata produktivitas mini purse seine perlakuan dan kontrol masing-masing sebesar 226 kg/haul dan 202 kg/haul.

Kata kunci: baited FADs, experimental fishing, ikan pelagis, mini purse seine, produktivitas
Multi-Scale Pooling In Deep Neural Networks For Dense Crowd Estimation
Authors: Radhan Ali Raza , Jokhio Fareed Ahmed , Hussain Ghulam , Javed Kamran , Ahmed Arsalan
Published: August 2022

State-of-the-art-methods for counting persons in dense crowded places lack in estimating accurate crowd density due to following reasons. They typically apply the same filters over a complete image or over big image patches. Only then the perspective distortion can be compensated by estimating local scale. It is achieved by training an additional classifier with the optimal kernel size chosen from limited choices. These methods are restricted to the context they are applied on because they are not end-to-end trainable; cannot justify quick scale changes because they allocate a single scale to big image patches; and can only utilize a narrow range of receptive fields for the networks to be of a feasible size. In this study, we bring in an end-to-end trainable deep architecture that merges features achieved from multiple kernels of different sizes and learns various essential features such as quick scale changes and to utilize the right context at each image location. This technique flexibly encodes scale of related information to precisely predict crowd density. The training and validation loss of the proposed approach is 5% and 4% lower than the state-of-the-art context aware method, respectively.
Design and Development of GUI for the Mitigation of Chromatic Dispersion: A New Approach
Authors: Das Bhagwan , Zardari Nawaz Ali , Deeba Farah , Ramnani Dileep Kumar
Published: August 2022

Chromatic Dispersion (CD) is the important effect that is considering for optical communication system design as it broadens the pulse during the propagation along channel resulting in pulse overlapping and ultimately bit errors raises. The increment in bit error, in result reduce the performance of optical system. Therefore, mitigation CD is necessary in order to improve the performance of optical communication system. There are several techniques of mitigating CD have been proposed and all based on coding based and this will create issues for the communication design engineer that every time the parameters need to be revised. In order to avoid this issue, the ease for the system design engineer has been created in designing the Graphical User Interface (GUI). In this work, GUI is designed and developed that will request the parameters need to be select for the optical system and it will describe the all process for mitigating it from the system. In the first, the communication system designer have to select the Transmission along with modulation and after that transmission at distance is asked in terms of km. The CD is mitigated uses least mean square technique and Fast Fourier Transform method. The further smoothing of signal is improved by Pulse shaping via using the raised cosine filter. In the end, the original signal and the compensated signal are defined. The BER is also calculated to show whether the reduction through DSP is performed. The GUI is developed in MATLAB and every button backhand the strong coding is used in C++ for developing the system. The designed and developed system offers the ease of use for the communication engineer, in which on one platform the user can observer well the optical system instead of programming.

Keywords: , , , .
MnO2@Co3O4 nanocomposite based electrocatalyst for effective oxygen evolution reaction
Authors: Solangi Muhammad Yameen , Samo Abdul Hanan , Laghari Abdul Jaleel , Aftab Umair , Abro Muhammad Ishaque , Irfan Muhammad Imran
Published: August 2022

For large-scale energy applications, conceiving low-cost and simple earth-abundant electrocatalysts are more difficult. By using an aqueous chemical technique, MnO2 was added into Co3O4 with varying concentrations to prepare MnO2@Co3O4 nanocomposite (CM). In an aqueous solution of 1 M KOH, the electrocatalyst with a greater concentration of MnO2 outperforms in terms of OER. To confirm the composition, crystalline structure, and morphology of the electrocatalyst, analytical methods such as X-ray diffraction (XRD) techniques, Fourier transformed infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were used. At 20 mA/cm2 current density, the electrocatalyst had a lowest overpotential of 310 mV verses Reversible hydrogen electrode (RHE). The CM-0.4 electrocatalyst has a small Tafel slope value and charge transfer resistance of approximately 72 mV/dec and 74 Ω which confirm its high catalytic activity. The electrocatalyst reveals a double layer capacitance (Rct) of 18 µF/cm2 and an electrochemical active surface area (ECSA) of 450 cm2, demonstrating that addition of MnO2 impurities into Co3O4 enhances the active catalyst sites. These findings contribute to the knowledge of these kind of catalysts, that will assist in the development of novel electrocatalysts which are feasible for prospective energy generation technologies.
Qualitative study on Hilfer-Katugampola fractional implicit differential equations
Authors:   Department of Mathematics, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia, Elsayed E. M. ,   Department of Mathematics, Faculty of Science, Mansoura University, Mansoura 35516, Egypt, Harikrishnan S. ,   Department of Mathematics, TIPS College of Arts and Science, Coimbatore, India, Vivek D. ,   Department of Mathematics, PSG College of Arts & Science, Coimbatore-641 014, India, Kanagarajan K. ,   Department of Mathematics, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, India
Published: August 2022

This paper solves implicit differential equations involving Hilfer-Katugampola fractional derivatives with nonlocal, boundary, and impulsive conditions. In addition, some sufficient conditions are formulated for the existence and uniqueness of solutions to the given problem, and Hyers-Ulam stability results are also presented.