bluuebunny/crossref_metadata_2025 huggingface dataset:
Conservation and Restoration of Mangroves in Response to Invasion of Spartina alterniflora Based on the MaxEnt Model: A Case Study in China
Authors: Cui Lina , Berger Uta , Cao Minmin , Zhang Yaqi , He Junming , Pan Lianghao , Jiang Jiang
Published: June 2023

In China, the invasion of Spartina alterniflora is an important driver for the decrease of mangrove area and ecological service functions related to this habitat. In the past few decades, S. alterniflora clearing and mangrove restoration projects have mainly focused on the areas where it is already changed but ignored the potential distribution areas. This study suggested that implementation of mangrove protection prior to the areas with the threat of S. alterniflora invasion could greatly improve protection efficiency and save costs. Thus, using Maximum Entropy Modeling (MaxEnt), we estimated the potential spatial distribution of both mangroves and S. alterniflora in China, considering the current distribution data, topographical, sediments, sea surface temperature and bioclimatic variables. What’s more, we identified and calculated the potential distributed areas in each province. We aimed to explore (i) the key factors determining the distribution of mangrove and Spartina alterniflora along the coastline and (ii) the hotspots of their competitive occurrence, including S. alterniflora invasion areas and mangroves degradation areas, in order to support mangrove conservation. The model showed that the distance to the coastline and the topography play important roles in the distribution of S. alterniflora, while mangroves were more sensitive to the range of the annual sea surface temperature. Our results furthermore confirm that S. alterniflora has a wider potential distribution area (~10,585 km2) than mangroves (~9124 km2) at the coastline of China; and predict the provinces Zhangzhou, Quanzhou, Zhanjiang, Beihai and Wenzhou as hotspots for the competition between mangroves and S. alterniflora. We propose that priority should be given to the protection or restoration of mangrove plants in those areas which are co-suitable for mangroves and S. alterniflora. In these areas, management measures should be conducted that hinder S. alterniflora invasions or clear existing S. alterniflora plants, firstly. This study provides guidance for the management of native species by preventing biological invasion.
Regeneration and Growth following Silvicultural Treatments in a Productive Central Hardwood Forest
Authors: Inglis Emily N. , Holzmueller Eric J. , Ruffner Charles M. , Groninger John W.
Published: June 2023

The lack of desirable oak (Quercus spp.) regeneration on upland sites is a problem in the Central Hardwood Region. While the reintroduction of fire, thinning, and/or harvesting has been proposed as a solution to increase oak regeneration, these treatments may have limited impact on productive sites, and the effects on the growth of residual midstory oak stems is not clear. This study examined the regeneration response and growth of residual midstory white oak (Quercus alba) stems in a mature, oak-dominated, upland forest following four treatments: (1) burn, (2) thin and burn, (3) harvest and thin and burn, and (4) no treatment (control) at Trail of Tears State Forest located in southern Illinois. Results indicated there was no significant difference in oak density among treatments for any regeneration size class. In addition, none of the treatments resulted in a radial growth release in residual midstory white oak stems. These results suggested these treatments may need to be modified to increase oak regeneration on productive sites and indicated that there may not have been enough time since treatment application, or treatments may not have been intense enough, to release midstory residual stems.
Mental Health Issues as a Consequence of the Pandemic: Group Psycho-Educational Intervention to Support Patients Recovered from COVID-19 Infection
Authors: Vagnini Denise , Lamperti Nicolò , Molgora Sara , Barile Francesca , Facchin Federica , Mazza Umberto , Saita Emanuela
Published: June 2023

Common psycho-physical symptoms have emerged in patients who were previously recovered for COVID-19 infection, including traumatic experience and enduring emotional disturbances. A group psycho-educational intervention of seven weekly sessions and a follow-up after three months was proposed to all Italian-speaking patients formally discharged from a public hospital in northern Italy and physically recovered from infection. Eighteen patients were recruited and divided into four age-homogenous groups, each led by two facilitators (psychologists and psychotherapists). The group sessions followed a structured format with thematic modules, including main topics, tasks, and homework assignments. Data were collected through recordings and verbatim transcripts. The objectives of the study were twofold: (1) to analyze the emerging themes and gain insight into the significant aspects of the participants’ lived experience of COVID-19, and (2) to examine changes in how participants approached these themes throughout the intervention process. Semantic-pragmatic text analyses, specifically thematic analysis of elementary context and correspondence analysis, were conducted using T-LAB software. Linguistic analysis revealed a congruence between the intervention’s objectives and the participants’ experiences. The study highlighted an evolution in the narratives, as participants transitioned from a passive and concrete perspective on the disease to a more comprehensive cognitive and emotional elaboration of their personal illness stories. These findings hold potential relevance for healthcare services and professionals working in this field.
The Impact of the Organization of Public Health Systems on the Ability of Countries to Resist the COVID-19 Pandemic: The Experience of Developed Countries of the World and Ukraine
Authors: Kuzior Aleksandra , Vasylieva Tetiana , Liuta Olga , Deineka Olha , Kashcha Mariia
Published: June 2023

The purpose of the study is to analyze the presence of functional interrelationships between the level of funding of the healthcare sector and the country’s ability to withstand any pandemic, using the example of the COVID-19 pandemic. Official indicators presented by the WHO, analytical reports by Numbeo (the world’s largest cost-of-living database), and the Global Health Security Index were used for the study. Using these indicators, the authors analyzed the following: the level of the spread of coronavirus infections in the world’s countries, the share of public expenditures on the development of the medical sphere in the GDP of the countries, and the development of the healthcare sector in 12 developed countries and Ukraine. These countries were grouped into three groups, based on the model of the organization of the healthcare sector (Beveridge model, Bismark model, Market (private) model). The Farrar–Glauber method was used to check for multicollinearity in the input dataset, and thirteen relevant indicators were selected. These indicators took part in the formation of the generalized characteristics of the country’s medical sphere and the ability to resist the pandemic. The state of readiness of countries to resist the spread of coronavirus infections was assessed using the country’s index of vulnerability to COVID-19 and the integral index of the development of medicine. Additive convolution was used in combination with sigma-limited parameterization to form an integral index of the country’s vulnerability to COVID-19 and to determine the weights of each indicator. The convolution of indicators according to the Kolmogorov–Gabor polynomial was used to construct an integral index of the development of medicine. Thus, while analyzing the ability of countries to resist the pandemic in terms of models of organization of the healthcare sector, it should be noted that none of the models demonstrated absolute effectiveness in the fight against the mass spread of COVID-19. The calculations made it possible to determine the nature of the relationship between the integral indices of the development of medicine and the vulnerability of countries to COVID-19, as well as a country’s potential ability to resist any pandemic and prevent the mass spread of infectious diseases.
COVID-19 and (Im)migrant Carers in Italy: The Production of Carer Precarity
Authors: Dotsey Senyo , Lumley-Sapanski Audrey , Ambrosini Maurizio
Published: June 2023

This article explores the impact of COVID-19 restrictions on foreign health workers in Italy. Focusing on caregivers in Lombardia, we explore what we call carer precarity, an emergent form of precarity resulting from pandemic restrictions exacerbating existing socio-legal vulnerabilities. The duality of the carer role—complete household and societal reliance in addition to simultaneous socio-legal marginalization—shapes their precarity. Utilizing data from 44 qualitative interviews with migrant care workers in live-in and daycare facilities that were conducted prior to and during the COVID-19 pandemic in Italy, we demonstrate how the migrant populations working in the care sector were particularly adversely affected due to their migratory status and working conditions. Migrants are excluded from or have differential access to a range of benefits or entitlements and are employed in undervalued work. Workers with live-in employment experienced tiered access to benefits plus the spatiality of restrictions, resulting in their near-complete confinement. Drawing on Gardner (2022) and Butler’s (2009) conceptualizations of precarity, we describe the emergence of a new form of pandemic-induced spatial precarity for migrant care workers at the nexus of gendered labor, limited mobility, and the spatiality of and a hierarchy of rights associated with migratory status. The findings have implications for healthcare policy and migration scholarship.
Accounting for Area Sources in Air Pollution Models
Authors: Venkatram Akula , Thiruvenkatachari Ranga Rajan
Published: June 2023

Area sources are important components of comprehensive air pollution models. The literature describes several approaches to modeling dispersion from such sources, but there is little consensus on an approach that can be applied to arbitrarily shaped area sources and is numerically efficient at the same time. This paper brings together ideas from previous work to propose an approach that meets these requirements. It is based on representing an area source as a set of line sources perpendicular to the wind direction; the number of line sources is determined by the specified precision of the concentration computed at a receptor impacted by the area source. Although AERMOD and the OML model incorporate versions of this approach, the open literature lacks an adequate description. This paper fills this important gap and also provides examples of its application. We show that different shaped area sources with the same emissions and emission density yield significantly different downwind concentration patterns. We then demonstrate the utility of the method through inverse modeling to estimate methane emissions from manure lagoons located in a dairy.
Being a Fair Neighbor—Towards a Psychometric Inventory to Assess Fairness-Related Perceptions of Airports by Residents—Development and Validation of the Aircraft Noise-Related Fairness Inventory (fAIR-In)
Authors: Hauptvogel Dominik , Schreckenberg Dirk , Rothmund Tobias , Schmitz Marie-Therese , Bartels Susanne
Published: June 2023

Aircraft noise causes a variety of negative health consequences, and annoyance is a central factor mediating stress-related health risks. Non-acoustic factors play an important role in the experience of annoyance where the aspect of fairness is assumed to be a vital component. This paper describes the development of the Aircraft Noise-related Fairness Inventory (fAIR-In) and examines its factorial validity, construct validity and predictive validity. The development of the questionnaire included expert consultations, statements from airport residents and a large-scale online survey around three German airports (N = 1367). Its items cover distributive, procedural, informational and interpersonal fairness. Via mailshot, almost 100,000 flyers were sent out in more (>55 dB(A) Lden)- and less (≤55 dB(A) Lden)-aircraft-noise-exposed areas around Cologne-Bonn, Dusseldorf and Dortmund Airport. Thirty-two items were carefully selected considering reliability, theoretical importance and factor loading calculated via exploratory factor analysis (EFA), with all facets achieving high internal consistency (α = 0.89 to 0.92). The factorial validity, analyzed via a confirmatory factor analysis (CFA), revealed that viewing distributive, procedural, informational and interpersonal fairness as distinct factors produced a better fit to the data than other categorizations with fewer factors. The fAIR-In shows adequate results in terms of construct validity and excellent results in terms of the predictive validity of annoyance by aircraft noise (r = −0.53 to r = −0.68), acceptance of airports and air traffic (r = 0.46 to r = 0.59) and willingness to protest (r = −0.28 to r = −0.46). The fAIR-In provides airport managers with a reliable, valid and easy-to-use tool to design, monitor and evaluate efforts to improve the neighborliness between an airport and its residents.
STAT3-Mediated Promoter-Enhancer Interaction Up-Regulates Inhibitor of DNA Binding 1 (ID1) to Promote Colon Cancer Progression
Authors: Lin Zhike , Liu Ying , Xu Tian , Su Ting , Yang Yingying , Liang Runhua , Gu Songgang , Li Jie , Song Xuhong , Liang Bin , Leng Zhijun , Li Yangsihan , Meng Lele , Luo Yijing , Chang Xiaolan , Huang Dongyang , Xie Lingzhu
Published: June 2023

Background: High expression of inhibitor of DNA binding 1 (ID1) correlates with poor prognosis in colorectal cancer (CRC). Aberrant enhancer activation in regulating ID1 transcription is limited. Methods: Immunohistochemistry (IHC), quantitative RT-PCR (RT-qPCR) and Western blotting (WB) were used to determine the expression of ID1. CRISPR-Cas9 was used to generate ID1 or enhancer E1 knockout cell lines. Dual-luciferase reporter assay, chromosome conformation capture assay and ChIP-qPCR were used to determine the active enhancers of ID1. Cell Counting Kit 8, colony-forming, transwell assays and tumorigenicity in nude mice were used to investigate the biological functions of ID1 and enhancer E1. Results: Human CRC tissues and cell lines expressed a higher level of ID1 than normal controls. ID1 promoted CRC cell proliferation and colony formation. Enhancer E1 actively regulated ID1 promoter activity. Signal transducer and activator of transcription 3 (STAT3) bound to ID1 promoter and enhancer E1 to regulate their activity. The inhibitor of STAT3 Stattic attenuated ID1 promoter and enhancer E1 activity and the expression of ID1. Enhancer E1 knockout down-regulated ID1 expression level and cell proliferation in vitro and in vivo. Conclusions: Enhancer E1 is positively regulated by STAT3 and contributes to the regulation of ID1 to promote CRC cell progression and might be a potential target for anti-CRC drug studies.
Molecular Farming of Pembrolizumab and Nivolumab
Authors: Stark Michael C. , Joubert Anna M. , Visagie Michelle H.
Published: June 2023

Immune checkpoint inhibitors (ICIs) are a class of immunotherapy agents capable of alleviating the immunosuppressive effects exerted by tumorigenic cells. The programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) immune checkpoint is one of the most ubiquitous checkpoints utilized by tumorigenic cells for immune evasion by inducing apoptosis and inhibiting the proliferation and cytokine production of T lymphocytes. Currently, the most frequently used ICIs targeting the PD-1/PD-L1 checkpoint include monoclonal antibodies (mAbs) pembrolizumab and nivolumab that bind to PD-1 on T lymphocytes and inhibit interaction with PD-L1 on tumorigenic cells. However, pembrolizumab and nivolumab are costly, and thus their accessibility is limited in low- and middle-income countries (LMICs). Therefore, it is essential to develop novel biomanufacturing platforms capable of reducing the cost of these two therapies. Molecular farming is one such platform utilizing plants for mAb production, and it has been demonstrated to be a rapid, low-cost, and scalable platform that can be potentially implemented in LMICs to diminish the exorbitant prices, ultimately leading to a significant reduction in cancer-related mortalities within these countries.
Transcriptome Sequencing and WGCNA Reveal Key Genes in Response to Leaf Blight in Poplar
Authors: Wang Ruiqi , Wang Yuting , Yao Wenjing , Ge Wengong , Jiang Tingbo , Zhou Boru
Published: June 2023

Leaf blight is a fungal disease that mainly affects the growth and development of leaves in plants. To investigate the molecular mechanisms of leaf blight defense in poplar, we performed RNA-Seq and enzyme activity assays on the Populus simonii × Populus nigra leaves inoculated with Alternaria alternate fungus. Through weighted gene co-expression network analysis (WGCNA), we obtained co-expression gene modules significantly associated with SOD and POD activities, containing 183 and 275 genes, respectively. We then constructed a co-expression network of poplar genes related to leaf blight resistance based on weight values. Additionally, we identified hub transcription factors (TFs) and structural genes in the network. The network was dominated by 15 TFs, and four out of them, including ATWRKY75, ANAC062, ATMYB23 and ATEBP, had high connectivity in the network, which might play important functions in leaf blight defense. In addition, GO enrichment analysis revealed a total of 44 structural genes involved in biotic stress, resistance, cell wall and immune-related biological processes in the network. Among them, there were 16 highly linked structural genes in the central part, which may be directly involved in poplar resistance to leaf blight. The study explores key genes associated with leaf blight defense in poplar, which further gains an understanding of the molecular mechanisms of biotic stress response in plants.
Salen-like Chromium and Aluminum Complexes as Catalysts in the Copolymerization of Epoxides with Cyclic Anhydrides for the Synthesis of Polyesters
Authors: Santulli Federica , Grimaldi Ilaria , Pappalardo Daniela , Lamberti Marina , Mazzeo Mina
Published: June 2023

Chromium and aluminum complexes bearing salalen ligands were explored as catalysts for the ring-opening copolymerization (ROCOP) of succinic (SA), maleic (MA), and phthalic (PA) anhydrides with several epoxides: cyclohexene oxide (CHO), propylene oxide (PO), and limonene oxide (LO). Their behavior was compared with that of traditional salen chromium complexes. A completely alternating enchainment of monomers to provide pure polyesters was achieved with all the catalysts when used in combination with 4-(dimethylamino)pyridine (DMAP) as the cocatalyst. Poly(propylene maleate-block-polyglycolide), a diblock polyester with a precise composition, was obtained by switch catalysis, in which the same catalyst was able to combine the ROCOP of propylene oxide and maleic anhydride with the ring-opening polymerization (ROP) of glycolide (GA) through a one-pot procedure, starting from an initial mixture of the three different monomers.
Stability Characterization of the Novel Anti-Cancer HM-10/10 HDL-Mimetic Peptide
Authors: Dempsey Michael P. , Andersen Katelyn E. , Wells Brittney M. , Taylor Mitchell A. , Cashman Clay L. , Conrad Lesley B. , Kearney Claire A. , Conklin Mary B. , Via Emily R. , Doe Emily M. , Komirisetty Ravikiran , Dearborn Susan , Reddy Srinivasa T. , Farias-Eisner Robin
Published: June 2023

Epithelial adenocarcinoma of the ovary and colon are associated with the highest rates of cancer-related deaths in women in the U.S. The literature supports the role of HDL-associated apolipoproteins in the treatment of cancer and other pro-inflammatory diseases. Previously, we developed a novel 20-amino acid mimetic peptide, HM-10/10, which potently inhibits tumor development and growth in colon and ovarian cancer. Here, we report the properties of HM-10/10 relative to its stability in vitro. The results demonstrated that HM-10/10 had the highest half-life in human plasma compared to plasma from other species tested. HM-10/10 demonstrated stability in human plasma and simulated gastric environment, increasing its promise as an oral pharmaceutical. However, under conditions modeling the small intestine, HM-10/10 demonstrated significant degradation, likely due to the peptidases encountered therein. Furthermore, HM-10/10 demonstrated no evidence of time-dependent drug–drug interactions, although it demonstrated CYP450 induction slightly above cutoff. As proteolytic degradation is a common limitation of peptide-based therapeutics, we are pursuing strategies to improve the stability properties of HM-10/10 by extending its bioavailability while retaining its low toxicity profile. HM-10/10 holds promise as a new agent to address the international women’s health crisis of epithelial carcinomas of the ovary and colon.
The Brain Pre-Metastatic Niche: Biological and Technical Advancements
Authors: Geissler Maximilian , Jia Weiyi , Kiraz Emine Nisanur , Kulacz Ida , Liu Xiao , Rombach Adrian , Prinz Vincent , Jussen Daniel , Kokkaliaris Konstantinos D. , Medyouf Hind , Sevenich Lisa , Czabanka Marcus , Broggini Thomas
Published: June 2023

Metastasis, particularly brain metastasis, continues to puzzle researchers to this day, and exploring its molecular basis promises to break ground in developing new strategies for combatting this deadly cancer. In recent years, the research focus has shifted toward the earliest steps in the formation of metastasis. In this regard, significant progress has been achieved in understanding how the primary tumor affects distant organ sites before the arrival of tumor cells. The term pre-metastatic niche was introduced for this concept and encompasses all influences on sites of future metastases, ranging from immunological modulation and ECM remodeling to the softening of the blood–brain barrier. The mechanisms governing the spread of metastasis to the brain remain elusive. However, we begin to understand these processes by looking at the earliest steps in the formation of metastasis. This review aims to present recent findings on the brain pre-metastatic niche and to discuss existing and emerging methods to further explore the field. We begin by giving an overview of the pre-metastatic and metastatic niches in general before focusing on their manifestations in the brain. To conclude, we reflect on the methods usually employed in this field of research and discuss novel approaches in imaging and sequencing.
An Unsupervised Graph-Based Approach for Detecting Relevant Topics: A Case Study on the Italian Twitter Cohort during the Russia–Ukraine Conflict
Authors: De Santis Enrico , Martino Alessio , Ronci Francesca , Rizzi Antonello
Published: June 2023

On 24 February 2022, the invasion of Ukraine by Russian troops began, starting a dramatic conflict. As in all modern conflicts, the battlefield is both real and virtual. Social networks have had peaks in use and many scholars have seen a strong risk of disinformation. In this study, through an unsupervised topic tracking system implemented with Natural Language Processing and graph-based techniques framed within a biological metaphor, the Italian social context is analyzed, in particular, by processing data from Twitter (texts and metadata) captured during the first month of the war. The system, improved if compared to previous versions, has proved to be effective in highlighting the emerging topics, all the main events and any links between them.
Local Community Detection in Graph Streams with Anchors
Authors: Christopoulos Konstantinos , Baltsou Georgia , Tsichlas Konstantinos
Published: June 2023

Community detection in dynamic networks is a challenging research problem. One of the main obstacles is the stability issues that arise during the evolution of communities. In dynamic networks, new communities may emerge and existing communities may disappear, grow, or shrink. As a result, a community can evolve into a completely different one, making it difficult to track its evolution (this is known as the drifting/identity problem). In this paper, we focused on the evolution of a single community. Our aim was to identify the community that contains a particularly important node, called the anchor, and to track its evolution over time. In this way, we circumvented the identity problem by allowing the anchor to define the core of the relevant community. We proposed a framework that tracks the evolution of the community defined by the anchor and verified its efficiency and effectiveness through experimental evaluation.
Glassy and Rubbery Epoxy Composites with Mesoporous Silica
Authors: Gkiliopoulos Dimitrios , Bikiaris Dimitrios , Efstathiadis Doukas , Triantafyllidis Konstantinos
Published: June 2023

The reinforcing efficiency of SBA-15-type mesoporous silica, when used as additive in epoxy polymers, was evaluated in this study. The effects of silica loading and its physicochemical characteristics on the thermal, mechanical, and viscoelastic properties of glassy and rubbery epoxy mesocomposites were examined using SBA-15 mesoporous silicas with varying porosities (surface area, pore size, and volume), particle sizes, morphologies, and organo-functionalization. Three types of SBA-15 were used: SBA-15 (10) with 10 nm pore diameters and long particles, SBA-15 (5) with 5 nm pore diameters and short particles, and SBA-15 (sc) with 10 nm pore diameters and short particles (“sc” for short channel). SBA-15 (10) was modified with propyl-, epoxy-, and amino-groups to study the effect of functionalization. The glassy or rubbery epoxy polymers and mesocomposites were produced by the crosslinking of a diglycidyl ether of bisphenol A (DEGBA) epoxy resin with isophorone diamine (IPD) or Jeffaminje D-2000, respectively. Mesoporous silica was uniformly dispersed inside the polymer matrices; however, the opacity levels between the rubbery and glassy samples were different, with completely transparent rubbery composites being prepared with as high as a 9 wt. % addition of SBA-15. The mechanical and thermal performance properties of the mesocomposites were dependent on both the type of the curing agent, which affected the cross-linking density of the pristine polymer matrix, and the characteristics of the mesoporous silica variants, being, in general, improved by the addition of up to 6 wt. % silica for the glassy polymers and up to 9 wt. % for the rubbery polymers.
Clonal Diversity of Candida auris, Candida blankii, and Kodamaea ohmeri Isolated from Septicemia and Otomycosis in Bangladesh as Determined by Multilocus Sequence Typing
Authors: Sathi Fardousi Akter , Aung Meiji Soe , Paul Shyamal Kumar , Nasreen Syeda Anjuman , Haque Nazia , Roy Sangjukta , Ahmed Salma , Alam Mohammad Monirul , Khan Shahed , Rabbany Mohammad Arif , Biswas Joy Prokas , Kobayashi Nobumichi
Published: June 2023

Candida auris, Candida blankii, and Kodamaea ohmeri have been regarded as emerging fungal pathogens that can cause infections with high mortality. For genotyping of C. auris, a multilocus sequence typing (MLST) scheme based on four locus sequences has been reported, while there is no typing scheme for C. blankii and K. ohmeri. In the present study, the existing MLST scheme of C. auris was modified by adding more locus types deduced from sequence data available in the GenBank database. Furthermore, MLST schemes of C. blankii and K. ohmeri were developed using the four cognate loci (ITS, RPB1, RPB2, D1/D2) and similar sequence regions to those of C. auris. These MLST schemes were applied to identify the ST (sequence type) of clinical isolates of C. auris (n = 7), C. blankii (n = 9), and K. ohmeri (n = 6), derived from septicemia or otomycosis in Bangladesh in 2021. All the C. auris isolates were classified into a single ST (ST5) and clade I, having a Y132F substitution in ERG11p, which is associated with azole resistance. Similarly, all the C. blankii isolates belonged to a single type (ST1). In contrast, six K. ohmeri isolates were assigned to five types (ST1-ST5), suggesting its higher genetic diversity. These findings revealed the availability of MLST schemes for these three fungal species for understanding their clonal diversity among clinical isolates.
Epidemiology, Modern Diagnostics, and the Management of Mucorales Infections
Authors: Pham David , Howard-Jones Annaleise R. , Sparks Rebecca , Stefani Maurizio , Sivalingam Varsha , Halliday Catriona L. , Beardsley Justin , Chen Sharon C.-A.
Published: June 2023

Mucormycosis is an uncommon, yet deadly invasive fungal infection caused by the Mucorales moulds. These pathogens are a WHO-assigned high-priority pathogen group, as mucormycosis incidence is increasing, and there is unacceptably high mortality with current antifungal therapies. Current diagnostic methods have inadequate sensitivity and specificity and may have issues with accessibility or turnaround time. Patients with diabetes mellitus and immune compromise are predisposed to infection with these environmental fungi, but COVID-19 has established itself as a new risk factor. Mucorales also cause healthcare-associated outbreaks, and clusters associated with natural disasters have also been identified. Robust epidemiological surveillance into burden of disease, at-risk populations, and emerging pathogens is required. Emerging serological and molecular techniques may offer a faster route to diagnosis, while newly developed antifungal agents show promise in preliminary studies. Equitable access to these emerging diagnostic techniques and antifungal therapies will be key in identifying and treating mucormycosis, as delayed initiation of therapy is associated with higher mortality.
Fear of COVID-19 Effect on Stock Markets: A Proposal for an Algorithmic Trading System Based on Fear
Authors: Paule-Vianez Jessica , Orden-Cruz Carmen , Gómez-Martínez Raúl , Escamilla-Solano Sandra
Published: June 2023

This study analyzes the fear of COVID-19 effect on European stock market returns. For this purpose, the search volumes (SV) collected by Google Trends (GT) and Wikipedia were used as proxies of fear of COVID-19. In a sample from 13 European stock markets, fear of COVID-19 was found to be associated with negative European stock returns. Our research employed this observation to propose an algorithmic trading system based on fear of COVID-19. Back-testing results show the possibility of extraordinary returns based on this system. These findings have important implications for political authorities, the mass media, and investors.
Comparative Study of the Relationship between Microstructure and Mechanical Properties of Aluminum Alloy 5056 Fabricated by Additive Manufacturing and Rolling Techniques
Authors: Evstifeev Alexey , Volosevich Darya , Smirnov Ivan , Yakupov Bulat , Voropaev Artem , Vitokhin Evgeniy , Klimova-Korsmik Olga
Published: June 2023

In recent years, additive manufacturing of products made from 5000 series alloys has grown in popularity for marine and automotive applications. At the same time, little research has been aimed at determining the permissible load ranges and areas of application, especially in comparison with materials obtained by traditional methods. In this work, we compared the mechanical properties of aluminum alloy 5056 produced by wire-arc additive technology and rolling. Structural analysis of the material was carried out using EBSD and EDX. Tensile tests under quasi-static loading and impact toughness tests under impact loading were also carried out. SEM was used to examine the fracture surface of the materials during these tests. The mechanical properties of the materials under quasi-static loading conditions exhibit a striking similarity. Specifically, the yield stress σ0.2 was measured at 128 MPa for the industrially manufactured AA5056_IM and 111 MPa for the AA5056_AM. In contrast, impact toughness tests showed that AA5056_AM KCVfull was 190 kJ/m2, half that of AA5056_IM KCVfull, which was 395 kJ/m2.
Investigations of Structural, Magnetic, and Electrochemical Properties of NiFe2O4 Nanoparticles as Electrode Materials for Supercapacitor Applications
Authors: Kumar Shalendra , Ahmed Faheem , Shaalan Nagih M. , Arshi Nishat , Dalela Saurabh , Chae Keun Hwa
Published: June 2023

Magnetic nanoparticles of NiFe2O4 were successfully prepared by utilizing the sol–gel techniques. The prepared samples were investigated through various techniques such as X-ray diffraction (XRD), transmission electron microscopy (TEM), dielectric spectroscopy, DC magnetization and electrochemical measurements. XRD data analysed using Rietveld refinement procedure inferred that NiFe2O4 nanoparticles displayed a single-phase nature with face-centred cubic crystallinity with space group Fd-3m. Average crystallite size estimated using the XRD patterns was observed to be ~10 nm. The ring pattern observed in the selected area electron diffraction pattern (SAED) also confirmed the single-phase formation in NiFe2O4 nanoparticles. TEM micrographs confirmed the uniformly distributed nanoparticles with spherical shape and an average particle size of 9.7 nm. Raman spectroscopy showed characteristic bands corresponding to NiFe2O4 with a shift of the A1g mode, which may be due to possible development of oxygen vacancies. Dielectric constant, measured at different temperatures, increased with temperature and decreased with increase in frequency at all temperatures. The Havrilliak–Negami model used to study the dielectric spectroscopy indicated that a NiFe2O4 nanoparticles display non-Debye type relaxation. Jonscher’s power law was utilized for the calculation of the exponent and DC conductivity. The exponent values clearly demonstrated the non-ohmic behaviour of NiFe2O4 nanoparticles. The dielectric constant of the nanoparticles was found to be >300, showing a normal dispersive behaviour. AC conductivity showed an increase with the rise in temperature with the highest value of 3.4 × 10−9 S/cm at 323 K. The M-H curves revealed the ferromagnetic behaviour of a NiFe2O4 nanoparticle. The ZFC and FC studies suggested a blocking temperature of ~64 K. The saturation of magnetization determined using the law of approach to saturation was ~61.4 emu/g at 10 K, corresponding to the magnetic anisotropy ~2.9 × 104 erg/cm3. Electrochemical studies showed that a specific capacitance of ~600 F g−1 was observed from the cyclic voltammetry and galvanostatic charge–discharge, which suggested its utilization as a potential electrode for supercapacitor applications.
CH3NH3PbI3/Au/Mg0.2Zn0.8O Heterojunction Self-Powered Photodetectors with Suppressed Dark Current and Enhanced Detectivity
Authors: Wang Meijiao , Zhao Man , Jiang Dayong
Published: June 2023

Interface engineering of the hole transport layer in CH3NH3PbI3 photodetectors has resulted in significantly increased carrier accumulation and dark current as well as energy band mismatch, thus achieving the goal of high-power conversion efficiency. However, the reported heterojunction perovskite photodetectors exhibit high dark currents and low responsivities. Herein, heterojunction self-powered photodetectors, composed of p-type CH3NH3PbI3 and n-type Mg0.2Zn0.8O, are prepared through the spin coating and magnetron sputtering. The obtained heterojunctions exhibit a high responsivity of 0.58 A/W, and the EQE of the CH3NH3PbI3/Au/Mg0.2Zn0.8O heterojunction self-powered photodetectors is 10.23 times that of the CH3NH3PbI3/Au photodetectors and 84.51 times that of the Mg0.2ZnO0.8/Au photodetectors. The built-in electric field of the p-n heterojunction significantly suppresses the dark current and improves the responsivity. Remarkably, in the self-supply voltage detection mode, the heterojunction achieves a high responsivity of up to 1.1 mA/W. The dark current of the CH3NH3PbI3/Au/Mg0.2Zn0.8O heterojunction self-powered photodetectors is less than 1.4 × 10−1 pA at 0 V, which is more than 10 times lower than that of the CH3NH3PbI3 photodetectors. The best value of the detectivity is as high as 4.7 × 1012 Jones. Furthermore, the heterojunction self-powered photodetectors exhibit a uniform photodetection response over a wide spectral range from 200 to 850 nm. This work provides guidance for achieving a low dark current and high detectivity for perovskite photodetectors.
Effect of Carbon Nanofibers on the Strain Rate and Interlaminar Shear Strength of Carbon/Epoxy Composites
Authors: Santos Paulo , Silva Abílio P. , Reis Paulo N. B.
Published: June 2023

The static bending properties, different strain rates and interlaminar shear strength (ILSS) of carbon-fiber-reinforced polymers (CFRP) with two epoxy resins nano-enhanced with carbon nanofibers (CNFs) are studied. The effect on ILSS behavior from aggressive environments, such as hydrochloric acid (HCl), sodium hydroxide (NaOH), water and temperature, are also analyzed. The laminates with Sicomin resin and 0.75 wt.% CNFs and with Ebalta resin with 0.5 wt.% CNFs show significant improvements in terms of bending stress and bending stiffness, up to 10%. The values of ILLS increase for higher values of strain rate, and in both resins, the nano-enhanced laminates with CNFs show better results to strain-rate sensitivity. A linear relationship between the logarithm of the strain rate was determined to predict the bending stress, bending stiffness, bending strain and ILSS for all laminates. The aggressive solutions significantly affect the ILSS, and their effects are strongly dependent on the concentration. Nevertheless, the alkaline solution promotes higher decreases in ILSS and the addition of CNFs is not beneficial. Regardless of the immersion in water or exposure to high temperatures a decrease in ILSS is observed, but, in this case, CNF content reduces the degradation of the laminates.
Superelastic Nickel–Titanium (NiTi)-Based Smart Alloys for Enhancing the Performance of Concrete Structures
Authors: Alshannag Mohammad J. , Alqarni Ali S. , Higazey Mahmoud M.
Published: June 2023

Recent advances in materials science have led to the development of smart materials that can continuously adapt to different loading conditions and changing environment to meet the growing demand for smart structural systems. The unique characteristics of superelastic NiTi shape memory alloys (SMAs) have attracted the attention of structural engineers worldwide. SMAs are metallic materials that can retrieve their original shape upon exposure to various temperatures or loading/unloading conditions with minimal residual deformation. SMAs have found increasing applications in the building industry because of their high strength, high actuation and damping capacities, good durability, and superior fatigue resistance. Despite the research conducted on the structural applications of SMAs during the previous decades, the existing literature lacks reviews on their recent uses in building industry such as prestressing concrete beams, seismic strengthening of footing–column connections, and fiber-reinforced concrete. Furthermore, scarce research exists on their performance under corrosive environments, elevated temperatures, and intensive fires. Moreover, the high manufacturing cost of SMA and the lack of knowledge transfer from research to practice are the main obstacles behind their limited use in concrete structures. This paper sheds light on the latest progress made in the applications of SMA in reinforced concrete structures during the last two decades. In addition, the paper concludes with the recommendations and future opportunities associated with expanding the use of SMA in civil infrastructures.
Thermoelectric Properties of Cotton Fabrics Dip-Coated in Pyrolytically Stripped Pyrograf® III Carbon Nanofiber Based Aqueous Inks
Authors: Paleo Antonio J. , Krause Beate , Cerqueira Maria F. , González-Domínguez Jose M. , Muñoz Enrique , Pötschke Petra , Rocha Ana M.
Published: June 2023

The transport properties of commercial carbon nanofibers (CNFs) produced by chemical vapor deposition (CVD) depend on the various conditions used during their growth and post-growth synthesis, which also affect their derivate CNF-based textile fabrics. Here, the production and thermoelectric (TE) properties of cotton woven fabrics (CWFs) functionalized with aqueous inks made from different amounts of pyrolytically stripped (PS) Pyrograf® III PR 25 PS XT CNFs via dip-coating method are presented. At 30 °C and depending on the CNF content used in the dispersions, the modified textiles show electrical conductivities (σ) varying between ~5 and 23 S m−1 with a constant negative Seebeck coefficient (S) of −1.1 μVK−1. Moreover, unlike the as-received CNFs, the functionalized textiles present an increase in their σ from 30 °C to 100 °C (dσ/dT > 0), explained by the 3D variable range hopping (VRH) model as the charge carriers going beyond an aleatory network of potential wells by thermally activated hopping. However, as it happens with the CNFs, the dip-coated textiles show an increment in their S with temperature (dS/dT > 0) successfully fitted with the model proposed for some doped multiwall carbon nanotube (MWCNT) mats. All these results are presented with the aim of discerning the authentic function of this type of pyrolytically stripped Pyrograf® III CNFs on the thermoelectric properties of their derived textiles.
Approaching Self-Bonded Medium Density Fiberboards Made by Mixing Steam Exploded Arundo donax L. and Wood Fibers: A Comparison with pMDI-Bonded Fiberboards on the Primary Properties of the Boards
Authors: Vitrone Federica , Brinker Sascha , Ramos Diego , Ferrando Francesc , Salvadó Joan , Mai Carsten
Published: June 2023

This study presents an unexplored method to produce formaldehyde-free MDF. Steam exploded Arundo donax L. (STEX-AD) and untreated wood fibers (WF) were mixed at different mixing rates (0/100, 50/50, and 100/0, respectively) and two series of boards were manufactured, with 4 wt% of pMDI, based on dry fibers, and self-bonded. The mechanical and physical performance of the boards was analyzed as a function of the adhesive content and the density. The mechanical performance and dimensional stability were determined by following European standards. The material formulation and the density of the boards had a significant effect on both mechanical and physical properties. The boards made solely of STEX-AD were comparable to those made with pMDI, while the panels made of WF without adhesive were those that performed the worst. The STEX-AD showed the ability to reduce the TS for both pMDI-bonded and self-bonded boards, although leading to a high WA and a higher short-term absorption for the latter. The results presented show the feasibility of using STEX-AD in the manufacturing of self-bonded MDF and the improvement of dimensional stability. Nonetheless, further studies are needed especially to address the enhancement of the internal bond (IB).
Peumus boldus Used in the Synthesis of ZnO Semiconductor Nanoparticles and Their Evaluation in Organic Contaminants
Authors: Maro Caree Abigail García , Gálvez Horacio Edgardo Garrafa , Olivas Osvaldo de Jesús Nava , Morales Mizael Luque , Hernández Diana Vargas , Flores Hugo Galindo , Carmona Víctor Manuel Orozco , Chinchillas Manuel de Jesús Chinchillas
Published: June 2023

The high demand for nanomaterials in the field of industry and science has forced researchers to develop new synthesis methods that are more efficient, economical, and environmentally friendly. At present, the application of green synthesis has taken a great advantage over conventional synthesis methods because it helps with the control of the characteristics and properties of the resulting nanomaterials. In this research, ZnO nanoparticles (NPs) were synthesized by biosynthesis using dried boldo (Peumus boldus) leaves. The resulting biosynthesized NPs had a high purity, quasi-spherical shape with average sizes ranging from 15 to 30 nm and a band gap of ~2.8–3.1 eV. These NPs were used in the photocatalytic activity of three organic dyes. The results showed degradation of 100% methylene blue (MB) in 180 min, 92% methyl orange (MO) in 180 min, and 100% Rhodamine B (RhB) in 30 min of exposure. These results show that the Peumus boldus leaf extract is effective in the biosynthesis of ZnO NPs with good photocatalytic properties.
Pyrolized Diatomaceous Biomass Doped with Epitaxially Growing Hybrid Ag/TiO2 Nanoparticles: Synthesis, Characterisation and Antibacterial Application
Authors: Brzozowska Weronika , Wojtczak Izabela , Railean Viorica , Bekissanova Zhanar , Trykowski Grzegorz , Buszewski Bogusław , Sprynskyy Myroslav
Published: June 2023

In the pursuit of innovative solutions for modern technologies, particularly in the design and production of new micro/nanostructured materials, microorganisms acting as “natural microtechnologists” can serve as a valuable source of inspiration. This research focuses on harnessing the capabilities of unicellular algae (diatoms) to synthesize hybrid composites composed of AgNPs/TiO2NPs/pyrolyzed diatomaceous biomass (AgNPs/TiO2NPs/DBP). The composites were consistently fabricated through metabolic (biosynthesis) doping of diatom cells with titanium, pyrolysis of the doped diatomaceous biomass, and chemical doping of the pyrolyzed biomass with silver. To characterize the synthesized composites, their elemental and mineral composition, structure, morphology, and photoluminescent properties were analysed using techniques such as X-ray diffraction, scanning and transmission electron microscopy, and fluorescence spectroscopy. The study revealed the epitaxial growth of Ag/TiO2 nanoparticles on the surface of pyrolyzed diatom cells. The antimicrobial potential of the synthesized composites was evaluated using the minimum inhibitory concentration (MIC) method against prevalent drug-resistant microorganisms, including Staphylococcus aureus, Klebsiella pneumonia, and Escherichia coli, both from laboratory cultures and clinical isolates.
Low Profile Dual-Band Polarization Conversion Metasurface with Omnidirectional Polarization
Authors: Zhang Jun-Jie , Xu Wei-Xi , Zhao Yu-Tong , Xie Han-Yu , Zu Hao-Ran , Wu Bian
Published: June 2023

In this work, a dual-band transmissive polarization conversion metasurface (PCM), with omnidirectional polarization and low profile, is proposed. The periodic unit of the PCM is composed of three metal layers separated by two substrates. The upper patch layer of the metasurface is the patch-receiving antenna, while the bottom layer is the patch-transmitting antenna. Both antennas are arranged in an orthogonal way so that the cross-polarization conversion can be realized. The equivalent circuit analysis, structure design, and experimental demonstration are conducted in detail, the polarization conversion rate (PCR) is greater than 90% within two frequency bands of 4.58–4.69 GHz and 5.33–5.41 GHz, and the PCR at two center operating frequencies of 4.64 GHz and 5.37 GHz is as high as 95%, with a thickness of only 0.062λL, where λL is the free space wavelength at the lowest operating frequency. The PCM can realize a cross-polarization conversion, when the incident linearly polarized wave at an arbitrary polarization azimuth, which indicates that it has the characteristics of omnidirectional polarization.