bluuebunny/crossref_metadata_2025 huggingface dataset:
A new selection criterion for voltage windows of aqueous zinc ion hybrid capacitors: achieving a balance between energy density and cycle stability
Authors: Zeng Fanda , Gong Xiliang , Xu Zijin , Du Zhengyan , Xu Jian , Deng Ting , Wang Dong , Zeng Yi , Yu Shansheng , Meng Zeshuo , Hu Xiaoying , Tian Hongwei
Published: November 2023

Connected link between by-products and potential windows, with basic zinc sulfate from ZHSs inhibiting hydrogen evolution to protect electrode material. Results show balancing energy density and cycling stability in ZHSs with the proposed criterion.
A highly selective, efficient hydrogen gas sensor based on bimetallic (Pd–Au) alloy nanoparticle (NP)-decorated SnO2 nanorods
Authors: Pandey Gaurav , Lawaniya Shiv Dutta , Kumar Sanjay , Dwivedi Prabhat K. , Awasthi Kamlendra
Published: November 2023

The surging worldwide demand for hydrogen highlights the crucial need for advanced detection technologies, essential for enhancing safety and optimizing utilization across various applications.
Multiobjective Electric Vehicle Charging Network Planning Considering Chance‐Constraint on the Travel Distance for Charging
Authors: Guo Yunxiang , Zhang Xinsong , Li Daxiang , Gu Chenghong , Lu Cheng , Ji Ting , Wang Yue
Published: November 2023

Electric vehicle charging stations (EVCSs) are important infrastructures to support sustainable development of electric vehicles (EVs), by providing convenient, rapid charging services. Therefore, the planning of electric vehicle charging network (EVCN) has attracted wide interest from both industry and academia. In this paper, a multiobjective planning model for EVCN is developed, where a fixed number of EVCSs are planned in the traffic network (TN) to achieve two objectives, i.e., minimizing both average travel distance for charging (TDfC) of EVs and investment costs of EVCN. According to the random characteristics of EVs’ TDfC, its constraint is presented as a chance constraint in the developed EVCN planning model. The nondominated sorting genetic Algorithm II with the constraint domination principle (NSGA‐II‐CDP) is customized to solve the developed multiobjective EVCN planning model, by designing a special coding scheme, a crossover operator, and a mutation operator. Then, a maximum gradient principle of investment revenue is designed to select the optimal planning strategy from the Pareto‐optimal solution set, when taking the investment return ratio as primary consideration. A 25‐node TN is used to justify the effectiveness of the developed methodology.
QIoTChain: Quantum IoT‐blockchain fusion for advanced data protection in Industry 4.0
Authors: Sharma Aditya Kumar , Peelam Mritunjay Shall , Chauasia Brijesh Kumar , Chamola Vinay
Published: November 2023

The modern world has its foundation built on data. Data is generated all the time, and many aspects of the society and economy are built upon it. In today's world, data is employed in better decision‐making, innovation, and improving the efficiency of systems. It becomes essential to protect it from being tampered with or misused. Encryptions based on cryptographic systems are used in mainstream data protection these days. There have been newer iterations of mechanisms based on new techniques using blockchain and the zero trust model and even systems that employ fog computing along with content delivery networks. The advent of computation through quantum technologies also helped in developing data security with post‐quantum mechanisms. The critical conditions for the working of these mechanisms hinder their adoption primarily. This also leads current systems to lack one or more of these technologies. Thus, the importance of a unified system that can employ quantum technologies effectively becomes prominent and requires a definitive investigation. In this article, a Quantum‐IoT‐based data protection scheme that can be of value to Industry 4.0 is analyzed. Light is also shed on innovations in quantum computing that can help solve not just current problems but also the future.
3D‐printed heterogeneous isotropic–anisotropic dielectric resonator for singly fed dual‐band circularly polarised antennas
Authors: de Araùjo Bruno , Morlaas Christophe , Pascaud Romain , Chabory Alexandre , Grzeskowiak Marjorie , Mazingue Gautier
Published: November 2023

The design of three‐dimensional (3D)‐printed heterogeneous ceramics exhibiting isotropic and anisotropic dielectric permittivities at microwave frequencies is studied for dielectric resonator antenna (DRA) applications. The heterogeneous ceramics are engineered by using periodic structures made up of subwavelength unit cells filled with zirconia ceramic and air. Ceramic stereolithography (CSLA) allows the 3D printing of a one‐piece ceramic block mixing isotropic and anisotropic dielectric regions. In order to demonstrate the possibility of exploiting such 3D‐printed ceramics, a singly fed dual‐band circularly polarised DRA is presented. To achieve circular polarisation at both bands, the relative permittivity of the dielectric resonator is locally controlled by introducing anisotropic dielectric regions. The 3D‐printed DRA is finally measured, and its results agree well with the simulations.
Effect of Demineralization on Gelatin Production from Grasshopper (Valanga nigricornis) as an Alternative of Halal Gelatin
Authors: Amalia Rizka , Allamah Masah Ulfah Labibah , Paramita Vita , Kusumayanti Heny , Butsaina Dhiya’ulhaq Syaikha , Anggara Maharani Noor , Puspa Amalia Nourma
Published: November 2023

Gelatin is a protein derivative product resulting from the collagen breakdown in a material. The protein content in dried grasshoppers, which are halal insects, reaches 40%. Hence, they have the potential to be produced as a substitute for non-halal gelatin. This study aims to determine the effect of various acid and base solvents and soaking time in the demineralization process on the characteristics of the gelatin. This study used a completely randomized design. The treatment of solvent types in the demineralization process used 6% HCl, 1% citric acid, 3% acetic acid, pineapple extract, and NaOH; while soaking times for treatment were 24 hours, 36 hours, and 48 hours. Each soaking time and solvent type in the demineralization process gave a significant effect on the yield value (P < 0.05). Demineralization treatment using 6% HCl for 48 hours showed gelatin with the best yield than other treatments, i.e., gelatin with a moisture content of 9.93%, ash content of 1.11%, and pH 5. The characteristics of gelatin in this study are under SNI 06-3735 of 1995.
Smart Crop Rotation For Sustainable Agriculture Against Climate Change Based On Local Wisdom
Authors: Wulandari Diah Ayu Retnani , Dewi Velia Aprita , Hidayat M. Arif
Published: November 2023

Rotation plant can in a manner effective reduce fragility system plant. Rotation plant need consider Lots factor. If happen error in election type plants, can lower results plant next. moment This rotation planting is done only based on estimate. exists artificial intelligence technology with use the Simple Multi Attribute Rating Technique (SMART) method that can used for optimization scheduling rotation plant. SMART is method weighting and calculation on determination scheduling rotation plant with determine ranking plant replacement in rotation plant based on criteria already determined. The criteria used namely botanical family, availability and needs water, and cost. Addition criteria based on culture on scheduling land agriculture as in a research pilot project in the region Java east use culture planting with “Pranata Mangsa” java’s calendar. Research results show application system supporters decision rotation plant use SMART method has accuracy by 90%. Ranking results sorted from percentage biggest until smallest.
Carbon Tax Policy Toward Net Zero Emission
Authors: Purwienanti Eiffeliena N.F. , Purwanto Purwanto
Published: November 2023

The use of fossil fuels as a primary energy source aims to meet the supply of energy needs. However, it is causing detrimental impacts on the environment in the form of pollutants and emissions of carbon dioxide as a greenhouse gas that have the potential for global warming. The net zero emission targets of various countries in 2050 and 2060 are used as a driving force to reduce the use of energy sources that cause greenhouse gas emissions. Furthermore, using renewable energies such as wind, solar, water and biomass energy replace fossil energy in an effort toward net zero emission. The policies of various countries to implement a carbon tax encourage renewable energy use to reach the net zero emission target. Indonesia targets net zero emission to be achieved by 2060 or even earlier. Thus, by 2030, it is targeted to reduce greenhouse gas emissions by 41% from BAU (business as usual) with international assistance and 26% without international assistance. Sweden's success in implementing a carbon tax starting in 1991, which has reduced greenhouse gas emissions by 35%, can be an example for other countries to implement a taxation system on fossil energy. The carbon tax implementation in Indonesia gradually starts on July 1, 2022, limited to coal-fired power plants (PLTU). It uses a cap and tax scheme, with tariffs applied to the number of emissions exceeding the set cap. Therefore, taxpayers can also take advantage of carbon certificates purchased on the carbon market to reduce their tax obligations.
Aspect-based sentiment analysis on student reviews using the Indo-Bert base model
Authors: Jazuli Ahmad , Widowati  , Kusumaningrum Retno
Published: November 2023

This study aims to gain a deeper understanding of online student reviews regarding the learning process at a private university in Indonesia and to compare the effectiveness of several algorithms: Naive Bayes, K-NN, Decision Tree, and Indo-Bert. Traditional Sentiment Analysis methods can only analyze sentences as a whole, prompting this research to develop an Aspect-Based Sentiment Analysis (ABSA) approach, which includes aspect extraction and sentiment classification. However, ABSA has inconsistencies in aspect detection and sentiment classification. To address this, we propose the BERT method using the pre-trained Indo-Bert model, currently the best NLP model for the Indonesian language. This study also fine-tunes hyperparameters to optimize results. The dataset comprises 10,000 student reviews obtained from online questionnaires. Experimental results show that the aspect extraction model has an accuracy of 0.890 and an F1-Score of 0.897, while the sentiment classification model has an accuracy of 0.879 and an F1-Score of 0.882. These results demonstrate the effectiveness of the proposed method in identifying aspects and sentiments in student reviews and provide a comparison between the four algorithms.
Crowdfunding Platform as an Open Innovation Model: The Importance of Effective Platform Governance
Authors: Juwita Oktalia , Isnanto R. Rizal , Prasetijo Agung B. , Slamin
Published: November 2023

Crowdfunding Platform (CFP) is another financing model that is different from the traditional financial institutions. CFP serves not only as a fundraising tool but also as a source of knowledge. CFP has several forms, namely equity-based, lending-based, reward-based, and donation-based. These forms of CFP divided into two classes, investment-based and non-investment-based. CFP is one form of platform Open Innovation (OI), where multiple stakeholders are involved in a funded project. OI refers to the collaborative innovation process. The involvement of multiple parties in OI leads to various risks that can result in collaboration failure, thus preventing the achievement of established CFP goals. Therefore, there is a need for effective governance in OI to manage potential conflicts, coordinate efficient knowledge sharing among the involved parties, and achieve the main objectives of the collaboration.
Performance Analysis of Islamic Banks in Indonesia Using Machine Learning
Authors: Ali Mahrus , Gernowo Rahmat , Warsito Budi
Published: November 2023

This study aims to examine several factors that influence the performance of Islamic banks in Indonesia by using the variables Return On Assets (ROA), Operating Expenses for Operating Income (BOPO), Capital Adequacy Ratio (CAR), Non Performing Financing (NPF), Financing to Deposit Ratio (FDR) and Potential Losses (PK). The data used in the study takes secondary data from the website of the Financial Services Authority (OJK) from the recapitulation of reports from Islamic banks throughout Indonesia, data taken from 2011 to 2020 which is a combination of Time series and cross section data. The analysis technique used is machine learning with multiple linear regression. The results of the study after being calculated using SPSS, the t table value is 2.776 and the F table value is 5.05. The final result is the hypothesis (H6) is accepted, which means that the variables X1, X2, X3, X4, X5 have a simultaneous effect on Y. Then the ROA value simultaneously influenced by the value of BOPO, CAR, NPF, FDR AND PK..
The Relationship Analysis of Phone Use to Accident Risk on Online Motorcycle Taxi in Semarang Using Logistic Regression
Authors: Azzahra Faradhina , Susanto Novie , Tantyo Aldama Muhammad
Published: November 2023

The existence of online motorcycle taxis had become increased. Besides, in Semarang, Indonesia the recorded number of online motorcycle taxis violation increased by 30% and the number of accidents involving online motorcycle taxis increased by 79% between 2018 and 2019. It was necessary to explore further whether the use of mobile phones on online motorcycle taxis plays a role in the number of motorcycle vehicle accidents. The factors used were demographics, frequency, time, safety and accident risk, and data obtained using a questionnaire. Online motorcycle taxi drivers in Semarang, Indonesia, were participated in this study as respondents. The data were processed by descriptive methods and logistics regression. This study found the high level of unawareness of respondent to obligate the rules in using cellphones while driving and the difficulty of respondents applying safety rules. We found that those factors were significantly affect the risk of accidents on motorcycle. In addition, this research also obtained a formulation related with the risk of accidents occurring in online motorcycle taxi drivers.
Analyzing The Effect of “Lantana Amara” Invasion on Density, Frequency, Dominance, And Important Value Index of Woody Species in The Lake Tana Sub Basin
Authors: Bayu Tesfaye , Soeprobowati Tri Retnaningsih , Adissu Solomon , Warsito Budi
Published: November 2023

Invasive plant species can disrupt recovery pathways by altering species interactions and ecosystem structure and functioning. The species compositional changes induced by Lantana invasion are primarily driven by gradual changes in species density. This research tries to analyze the effect of
Lantana camara invasion of density, dominance, important value index, species richness, and evenness in the Lake Tana subbasin. The finding revealed that species dominance (48.36) in the not invaded area is higher than invaded area (121.07). The total number of species recode in invaded (2031) area was lower than in the uninvaded area (5085). The uninvaded area (3.73) is richer in terms of species composition than invaded area (2.84). The invasive species
Lantana camara affects the density, frequency, and important value index of other species by suppressing their composition. It also affects the species distribution by affecting species evenness and richness of the study area. The invasive species affect biodiversity composition and ecosystem services in the Lake Tana sub-basin. Comprehensive management strategies should be designed by the government, policymakers, and environmentalists to minimize the effect of Lantana camara invasion on biodiversity composition.
Utilization of Rice Straw into Bioethanol through Biological Pathways
Authors: Sukma Andhika Cahaya Titisan , Budiyono Budiyono , Al-Baarri Ahmad Ni'matullah
Published: November 2023

The increasing burning of fossil fuels and changes in land use and forestry increase the CO2 in the earth's atmosphere. This condition increases the earth's global temperature, thus causing climate change. In addition, the volume of rice straw waste is very abundant, and the most popular treatment is burning in rice fields. This process also contributes to air pollution and an increase in CO2 gas. Meanwhile, straw is lignocellulosic biomass containing cellulose and hemicellulose as a source of sugar to be converted into bioethanol. Lignocellulosic biomass conversion consists of three main stages, pretreatment, hydrolysis, and fermentation. The process of converting rice straw into bioethanol has been developed. However, the current obstacle is that the conversion process requires high energy, produces chemical waste, and is not environmentally friendly. A biological approach is preferred so that the rice straw conversion process becomes more sustainable. This paper reviews the pretreatment, hydrolysis, and fermentation processes in biologically converting rice straw into bioethanol. Thus it is expected to be able to respond to existing challenges through a biological and more environmentally friendly approach.
The Relationship Between Environmental Factors And Community Behavior With The Incidence of Dengue Hemorrhagic Fever (DHF) In The Working Area of The Lospalos Health Center Lautem Regency East Timor
Authors: da Costa Vaz Gaio Benigna , Martini  , Sutingsih Dwi
Published: November 2023

Dengue hemorrhagic fever (DHF) is an infectious disease caused by a virus Arbovirus known as the genus flavivirus family flaviviridae transmitted by the bite of the mosquito Aedes aegypti. Knowing the relationship between environmental factors and community behavior with the incidence of Dengue Hemorrhagic Fever (DHF) in the working area of the Lospalos Health Center, Lautem Regency. This type of research is an observational analytical study with a Control case approach. The study respondents amounted to 96 people according to the specified criteria selected by the simple random sampling method. Data collection was carried out by questionnaires and interviews. Data analysis was performed using chi square and multiple logistic regression. Environmental and behavioral factors of the community associated with the incidence of dengue hemorrhagic fever (DHF) are occupancy density (p = 0.000), frequency of landfill draining (p = 0.000), extension experience (p = 0.002), knowledge (p = 0.000), action (p = 0.007), presence of larvae (p = 0.008) and place of presence of larvae (p = 0.002) while what is not related is attitude (p = 0.037). The most dominant variable is Knowledge with an OR of 30.37 (9.899-93.181) public knowledge has the most influence on the incidence of bloody fever. Health workers should provide more counseling to increase public knowledge.
Sustainable policy and planning of Borobudur Tourism Village, Central Java post Covid-19 Pandemic
Authors: Oktavilia Shanty , Wahyuningrum Indah Fajarini Sri , Utami Sri , Damayanti Nadia
Published: November 2023

This study aims to identify potential mapping and analyze the problems faced by tourism village entrepreneurs in the Borobudur Tourism Area, Central Java after the pandemic. This study uses primary and secondary data. Quantitative analysis using descriptive analysis method is considered appropriate to describe the potential conditions and problems faced by tourism village entrepreneurs. This research obtained the results that each village has a uniqueness that can be raised and collaborated on in the form of inter-village tour packages. The problems faced by tourist villages are relatively homogeneous because they have the same socio-cultural background. The highest approval was mainly in an effort to increase the segment and target market for tourism objects and develop tourism activities and attractions based on local wisdom. The relationship between actors/stakeholders in the development of a tourist village in the Borobudur Tourism Area shows a very strong relationship. The implication of this research is that the unique potential of each village spread across the Borobudur Tourism Area can be addressed and managed wisely by business actors so that they can provide economic and community benefits.
The Role of the Social Environment and Social Capital in Improving the Welfare of Returning Migrants in Central Java
Authors: Suyanto Suyanto
Published: November 2023

The aims of this study are: (1) to explain the use of social capital in improving the welfare of returning migrant households; (2) to explain the interaction of the social environment and social capital in determining the welfare of the household; (3) identifying stakeholders in improving the welfare of returning migrants. The research design is a survey and case study. This study chose the research location in Central Java. Determination of the sample using the technique of multi-stages and purposive sampling. Collecting data using observation, structured interviews, and in-depth interviews.Data analysis uses descriptive statistics, the descriptive statistical and qualitative analysis and categorical. Return migrants more than 40 percent still maintain contact and always keep in touch. Actors involved in organizing return migrants are NGOs, companies, government, and religious organizations. The obstacle for returning migrants to increasing household welfare from the use of social capital is that there are still very few returning migrants who are members of organizations, those who join organizations are also just for non-productive communication, organizations are only a place to meet misses and mutual help. The social environment is more dominated by various traditional practices, limited to those who know them well, there is less innovation.
A Saprobic Index for quality of Minapadi Water and the Fish Osmotic Performance Level of Minapadi
Authors: Siregar Zaenal Arifin , Anggoro Sutrisno , Irianto Hari Eko , Purnaweni Hartuti
Published: November 2023

Ending hunger is one of the Sustainable Development Goals (SDG) that must be achieved to achieve prosperity. The supply of these food needs connects with human dwelling requirements. Numerous technologies have been developed to solve these difficulties. One of these technologies is minapadi, which uses land effectively. For sustainability objectives to be realized, using such technology must preserve environmental quality. This research intends to assess changes in water quality resulting from the usage of minapadi, as well as fish osmosis performance in minapadi. This research is performed to determine the effect of minapadi technology on water and fish. Samberembe Sleman is the location that has been adopting minapadi for a long time and is the Food and Agriculture Organization of the United Nations (FAO) pilot site. In order to acquire data for use in computing the Tropic Saprobity Index, the minapadi water of Samberembe was collected monthly for four months during the study. Blood samples from tilapia (Oreochromis niloticus) were collected in the fourth month to determine osmotic performance levels. The acquired findings have the highest SI value of 0.986 and the lowest SI value of 0.968. The state of β (meso/oligo saprobik) has the highest TSI value with a value of 1.011, while the state has the lowest TSI value with a value of 0.995 β (meso saprobik). Iso-hyperosmotic is the pattern of osmoregulation in tilapia (Oreochromis niloticus) in minapadi. Stable SI and TSI levels at Minapadi do not fluctuate. This result suggests that the water quality is with lightly contaminated water, yet the TSI value indicates that the water is fertile and potable. The normal condition of fish in minapadi indicates that the use of minapadi does not affect environmental conditions.
Microplastic Pollution in Indonesia: The Contribution of Human Activity to the Abundance of Microplastics
Authors: Setyaningsih Wahyu , Hadiyanto Hadiyanto , Triadi Putranto Thomas
Published: November 2023

Plastic in Indonesia are used as wrappers on household scale to large industrial products. To reach low-income consumers the company releases cheap plastic products and daily necessities in smaller plastic wrap which causes high use of plastics even in rural areas and causes macro to micro-sized plastics pollution. This study used a systematic literature review method. Google Scholar and Science Direct databases are used in this literature study. The inclusion criteria in selecting articles to be reviewed contain the keywords "microplastic", "microplastic abundance" and "urban areas". Based on these criteria 32 articles published since 2014. Most of the research was carried out in coastal and marine environment. The greatest abundance of microplastic is found in coastal areas sediments and estuary water. The dominant forms are fragments and fibers with polypropylene (PP) and polyethylene (PE) types. The morphology and types indicate that the source is secondary microplastics mostly comes from human activities in urban areas. More microplastic research is needed in Indonesia, especially in the terrestrial area including in soil and groundwater to identify the main sources of pollution, the effect of waste management on microplastic abundance and identify pathways for microplastic pollution from land to the sea.
Filtration Test Fe3+ by Duck Feather -Na2S2O5 - High Dencity Polyethylene (HPDE) Composite
Authors: Utami Umi Baroroh Lili , Ariyani Dahlena
Published: November 2023

The problem of disposing of waste into the aquatic environment is heavy metal pollution such as iron (Fe). The manufacture of High Dencity Polyethylene (HDPE) plastic composites with keratin from duck feathers is expected to overcome these problems. This composite was made for duck feathers with 0.325M Na2S2O5 and continued with the percentage between HDPE polyethylene and duck feathers at 30:70. HDPE was dissolved using xylen and benzoyl peroxide and anhydrous maleic acid were added at a temperature of 145oC and duck feathers were added which had been activated with 0.325M Na2S2O5. While stirring until blended, then molded to form pellets while still hot. The continuous filtration test was carried out by placing the composite in a cylindrical tube made of glass with a weight of 4 grams, a flow rate of 200 ml/min. The concentration of iron (Fe) flowed was 100 ppm, and measurements of the water flow were carried out for every 200 ml. The adsorption capacity was calculated using the Thomas Equation. The results showed that the continuous absorption of Fe3+ duck feather composite- Na2S2O5 -HDPE showed that the adsorption capacity was 93.302 mg/g.
Structural Equation Model Determinants of Risk Factors for Hypertension Status in Urban Areas in Kotabumi 1 Community Health Center, North Lampung Regency, Lampung Province, Indonesia
Authors: Aryanti Sri , Wulan Sumekar Rengganis Wardani Dyah , Fatriyadi Suwandi Jhons , Bakri Samsul , Tugiyono
Published: November 2023

WHO, 2021 estimates 1.28 billion adults aged 30-79 years worldwide suffer from hypertension. Identify the significant influence of socio-economic factors and risk factors for the occurrence of hypertension status and prove the hypothesis. Case and control studies in November-December 2022 328 samples, 164 case groups and 164 control groups aged > 18 years who live in the urban area of the Kotabumi Health Center I North Lampung Regency, Lampung Province, Indonesia. Latent variables consist of Hypertension, Socio-economy, Environmental, Lifestyle, and Health Services, which are measured through appropriate indicators. Data collection was carried out through observation, in-depth interviews and questionnaires. Data analysis with Structural Equation Modeling (SEM) PLS 3.0. Determinants of socio-economic variables, health services, environment and lifestyle have a significant relationship to the incidence of hypertension by 55.8% in urban areas of North Lampung Regency, indicating that education, access to health services, stress levels and physical activity affect the status of events is the strongest indicator in explaining the causes of hypertension. This research can support the hypertension control program by improving socio-economic. health services through increased access to health services, the environment to reduce stress levels, and lifestyle through increased physical activity. It needs the support of other stakeholders, especially in urban areas in low-income countries and middle class who have socioeconomic as the main problem that caused the incident hypertension, including Indonesia.
La myopathie centronucléaire liée au gène de la dynamine 2
Authors: Bitoun Marc
Published: November 2023

La myopathie centronucléaire autosomique dominante (AD-CNM) est une myopathie congénitale rare caractérisée par une faiblesse musculaire et par la présence de noyaux centraux dans les fibres musculaires en absence de tout processus de régénération. L’AD-CNM est due à des mutations du gène DNM2 codant la dynamine 2 (DNM2), une volumineuse GTPase impliquée dans le trafic membranaire intracellulaire et un régulateur des cytosquelettes d’actine et de microtubules. Les mutations de la DNM2 sont associées à un large éventail clinique allant de formes sévères néonatales à des formes moins graves à début plus tardif. La signature histopathologique inclut une centralisation nucléaire, une prédominance et une atrophie des fibres lentes, ainsi que des travées sarcoplasmiques en rayons de roue. Pour expliquer la dysfonction musculaire, plusieurs mécanismes physiopathologiques affectant des étapes clés de l’homéostasie musculaire ont été identifiés. Ils incluent des défauts du couplage excitation-contraction, de la régénération musculaire, des mitochondries ou de l’autophagie. Plusieurs approches thérapeutiques sont en développement, en particulier la modulation de l’expression de la DNM2 pan-allélique ou ne ciblant que l’allèle muté, ouvrant ainsi la porte à des essais cliniques dans cette pathologie.
Weiter wollen – Personalentwicklung bei Mitarbeitenden mit psychischen Problemen
Authors: von Eisenhart Rothe Anna
Published: November 2023

Die Zahlen der Krankschreibungen aufgrund psychischer Erkrankungen steigen und steigen. Die letzten Jahre beschleunigten diese Entwicklung rasant, und auch Therapeuten und Therapeutinnen sind betroffen. Will man diese Mitarbeitenden halten, fördern und will man verhindern, dass sich Lernblockaden manifestieren, gilt es zu handeln. Schließlich sind Fachkräfte so rar wie nie. Eine engagierte Personalentwicklung kann helfen, Mechanismen entgegenzuwirken, die die berufliche Weiterentwicklung ausbremsen.
Komplexes Wunderwerk – Wundheilung
Authors: Herberhold Malte
Published: November 2023

Das Thema Wundheilung bildet die Basis vieler Heilungsprozesse, die auch Physiotherapeut*innen begleiten. Dabei ist es wichtig, bei den Einflussfaktoren Hygiene, Stress, Aktivität, Schlaf und Ernährung auf dem neuesten Wissensstand zu sein.
„Haben Sie kurz Zeit?“ – Maier-Kolumne
Authors: Maier Ulrike
Published: November 2023

Physiotherapeutin im Krisenmodus im Post-Corona- und Energienot-Zeit-alter. Lesen Sie, wie in dieser Gemengelage Worte jeden Praxisalltag sprengen.
Advances in the Synthesis of Spirocyclic Nucleosides
Authors: Kumar Sumit , Khan Yousuf , Arora Aditi , Sharma Vivek K. , Singh Sunil K. , Kumar Manish , Rungta Pallavi , Singh Brajendra K.
Published: November 2023

The nucleosides are the building blocks for nucleic acids and composed of a five-carbon sugar bearing either pyrimidine or purine nucleobase. The biological properties of nucleosides can be tailored by chemically modifying the five-carbon sugar to influence its sugar pucker. The spirocyclic scaffold is an indispensable scaffold in more than ten approved drugs, and its inherent three-dimensionality makes it an ideal modification to influence the sugar pucker and biological properties of nucleosides. However, the introduction of spirocyclic scaffold is often synthetically challenging due to increase in synthetic steps and stereocenters. The present review highlights the advances in synthetic methodologies developed during the past decades for accessing various members of the spiro-functionalized nucleoside family.

1 Introduction

2 C-1′-Spirocyclic Nucleosides

3 C-2′-Spirocyclic Nucleosides

4 C-3′-Spirocyclic Nucleosides

5 C-4′-Spirocyclic Nucleosides

6 Miscellaneous Spirocyclic Nucleosides

7 Conclusion and Future Perspectives
Homoeopathic Management of Male Infertility—A Case Series
Authors: Kumar K.B. Dileep , Rath Padmalaya , Thakur Tushita
Published: November 2023

Background and Objectives Male infertility means a man is not able to start a pregnancy with his female partner. Infertility affects 10 to 15% of the couples globally. Male factor infertility contributes to about 20 to 30% of the cases. Low sperm concentration, poor sperm motility and abnormal sperm morphology are the main etiological factors for male infertility. For some patients, high cost of conventional treatment can be a deterrent while some fail to respond to it. Therefore, there is a need to explore the role of homoeopathy as an alternative.

Methods Five male patients with infertility were treated with homoeopathic medicine based on the totality of symptoms after consulting repertory and Materia Medica. Further studies with suitable sample size are the cases were followed up with laboratory investigations are reported according to the HOM-CASE guidelines.

Results Improvement was guaged by sperm analysis of all five men during treatment and all five cases resulted in pregnancy.

Conclusion Further studies with suitable sample size are Warranted for further validation of the results.
An Evidence-Based Case Report of Female Infertility Treated with Individualised Homoeopathic Medicine
Authors: Pandit Raj K.
Published: November 2023

Introduction Infertility is defined as the failure to conceive within 1 or more years of regular unprotected coitus. The World Health Organization (WHO) estimates the overall prevalence of primary infertility in India to be between 3.9 and 16.8%. Medical therapy includes the treatment of reversible endocrine or infectious causes of subfertility. In the medical literature, case reports of infertility are scanty. We aimed to report a case treated with homoeopathic constitutional medicine in a lady suffering from infertility.

Case summary A female patient, aged 30, married for 6 years, presented with a complaint of having no issue despite treatment of infertility for a couple of years by a reproductive endocrinologist. Subsequent investigations showed that her ovarian reserve was inadequate. She was encouraged to undergo in vitro fertilisation because her husband's semen analysis report was normal. She decided to take homoeopathic treatment and received individualised care based on the holistic tenets of homoeopathy. After 3 months of treatment with the constitutional homoeopathic drug Natrum muriaticum, she became pregnant and gave birth to a healthy boy at term. This case report demonstrates the beneficial effects of individualised homoeopathy on infertility. The Modified Naranjo Criteria score (MONARCH) showed causal attribution of changes in her condition to the homoeopathic treatment.
Aberrant Right Subclavian Artery—To Test or Not to Test, That Is the Question
Authors: Chawla Gurnihal , Balakrishnan Bijoy K. , Batra Meenu , Sidhik Afshana , Laad Aditi , Patil Swapneel N. , Madhusoodhanan Lipi , Gopinathan K. K.
Published: November 2023

Objectives This study aimed to determine if isolated fetal aberrant right subclavian artery (ARSA) is associated with an increased risk of chromosomal abnormalities and to see whether or not invasive testing should be considered.

Methods We conducted a retrospective study from January 2017 to December 2021. All prenatally diagnosed cases of ARSA were reviewed and their clinical data were collected. Amniocentesis was advised after genetic counseling in every case of ARSA.

Results One hundred and thirteen patients of ARSA were diagnosed at 21.2 ± 2.4 weeks of gestational age. Eighty-eight fetuses had isolated ARSA. Eighty-three patients underwent amniocentesis. Of those, six had Down syndrome and one had Turner syndrome. Four fetuses with genetic abnormalities had no other ultrasound findings; however, the association of isolated ARSA with chromosomal abnormalities was not statistically significant (p-value = 0.998). Ten patients underwent termination of pregnancy including seven with chromosomal abnormalities and three fetuses with other structural anomalies. The mean age of postnatal follow-up was 2.2 years. Mild respiratory distress was seen in one fetus. No neonatal intensive care unit admissions were present.

Conclusion Isolated ARSA by itself does not significantly increase the risk of associated chromosomal abnormalities. The detection of fetal ARSA, however, mandates a detailed fetal ultrasound. Invasive testing can be deferred in cases of isolated ARSA. Larger prospective studies are required to see the role of cell-free DNA as an optimal alternative option.
Updates in Cleft Care
Authors: Parham Matthew J. , Simpson Arren E. , Moreno Tanir A. , Maricevich Renata S.
Published: November 2023

Cleft lip and/or palate is a congenital malformation with a wide range of presentations, and its effective treatment necessitates sustained, comprehensive care across an affected child's life. Early diagnosis, ideally through prenatal imaging or immediately postbirth, is paramount. Access to longitudinal care and long-term follow-up with a multidisciplinary approach, led by the recommendations of the American Cleft Palate Association, is the best way to ensure optimal outcomes. Multiple specialties including plastic surgery, otolaryngology, speech therapy, orthodontists, psychologists, and audiologists all may be indicated in the care of the child. Primary repair of the lip, nose, and palate are generally conducted during infancy. Postoperative care demands meticulous oversight to detect potential complications. If necessary, revisional surgeries should be performed before the child begin primary school. As the child matures, secondary procedures like alveolar bone grafting and orthognathic surgery may be requisite. The landscape of cleft care has undergone significant transformation since early surgical correction, with treatment plans now tailored to the specific type and severity of the cleft. The purpose of this text is to outline the current standards of care in children born with cleft lip and/or palate and to highlight ongoing advancements in the field.
Dosage of Alcohol, Cocaine and Marijuana in Patients with Moderate and Severe Traumatic Brain Trauma Attended at the Hospital of Clinics of the Federal University of Uberlândia
Authors: Dias Paulo César Marinho , Resende Elmiro Santos , Faria José Weber Vieira de
Published: November 2023

Introduction In Brazil, there are 125,000 hospitalizations a year for traumatic brain injuries (TBI) at a high socio-economic cost, causing serious and permanent sequelae, often associated with the use of alcohol, cocaine and marijuana.

Objective to discover the epidemiological characteristics of patients with moderate and severe TBI, treated at the Emergency Room of the Hospital of Clinics of the Federal University of Uberlândia (UFU), and their association with the use of alcohol, cocaine and marijuana.

Material and Methods saliva and urine samples were collected from 80 patients with moderate and severe TBI, aged ≥18 years, between September 2020 and December 2021. Research was made into the use of alcohol, cocaine and marijuana, using chromatographic immunoassay test kits.

Results A total of 28 cases (35%) were positive for alcohol, 22 cases for marijuana (27.5%) and 23 cases for cocaine (28.7%). The average age was 41 years old, with a predominance between 20 to 49 years old and of the male sex (90%). Accidents occurred mainly at night (52.5%) and on weekdays (65%). The most frequent cause of accident was transport (53.8%), followed by falls (22.5%) and aggression (16.2%). Of the transport accidents, motorcycle and automobiles accidents predominated (28.75%). Overall mortality was 16.2%, with zero positive cases for alcohol, 17.4% positive for cocaine and 27.3% positive for marijuana.

Conclusion we observed an association between TBI, alcohol, marijuana and cocaine, as well as an increase in cocaine and marijuana cases when compared with a study performed at this institution in 2003.
Ein Extremitätenschmerz, der keiner ist – Arm- und Beinschmerzen aus der Wirbelsäule
Authors: Supp Georg
Published: November 2023

Bei einem isolierten Schmerz an den Extremitäten empfiehlt die Literatur bisher kein Screening der Wirbelsäule. In der Praxis findet es schon gar nicht statt. Die EXPOSS-Studie zeigt nun, dass die Wirbelsäule sogar häufig für solche Beschwerden verantwortlich ist. Der Artikel zeigt, wie diese Erkenntnis in den Alltag umgesetzt werden kann.
Modeling the significance of work culture on burnout, satisfaction, and psychological distress among the Gen-Z workforce in an emerging country
Authors: Chen Xuelin , Masukujjaman Mohammad , Al Mamun Abdullah , Gao Jingzu , Makhbul Zafir Khan Mohamed
Published: November 2023

Human resources are widely recognized as critical factors for promoting sustainable development in organizations. However, the evolving workplace landscape and uncertainties pose significant challenges to Gen Z workers in China, leading to increased psychological distress and decreased performance. This study investigates the effects of 996 work culture, work overload, perceived career development opportunities, and perceived pay for performance on the psychological distress experienced by Chinese Gen Z workers. Using a quantitative and cross-sectional approach, we obtained 676 responses from Chinese Gen Z workers. We also utilized partial least squares structural equation modeling to examine and forecast the extent of the impact of the independent variables. The empirical findings reveal that 996 work culture and work overload indirectly influence the psychological distress of Gen Z workers in China via job burnout and job satisfaction; whereas perceived career development opportunities and perceived pay for performance indirectly influence their psychological distress via job satisfaction. Our research extends the existing literature by providing insights into the complex associations between various work-related factors (particularly 996 work culture) and psychological distress among Gen Z workers in China. Regarding policy implications, this study emphasizes the significance of considering the mental health of young employees as a crucial aspect of organizational management and suggests practical measures that organizations can adopt to ensure long-term psychological well-being and workforce engagement.
Exhibiting fashion on the heritage site: the interrelation between body, heritage space, and fashionable clothing
Authors: Lan Lan , Liu Peng
Published: November 2023

The article examines a fashion exhibition at a heritage museum on a historic site in terms of fashion museology. Fashion museology, which has emerged from the growing phenomenon of exhibiting fashion in museums, advocates the visual representation and holistic atmosphere of the curatorial space that determines the on-site audience experience. This article focuses on how the interrelation between fashionable clothing, the bodies of the audience, and the heritage space constructs a hybrid space in which bodily movement articulates the displayed clothing. We consider the heritage space to be a performative event and explore how heritage museums can harness and make practical use of the affective interrelationship within the designed museum space in terms of the quality of the fashion exhibition experience. Museum audiences are situated in and moved around by the curated spatial environment, which is a space with cultural residuals and historical inheritance, where the bodily encounter with the displayed clothing occurs. The investigation of this interaction via case studies sheds light on the overlooked haptic experience and spatial storytelling in fashion exhibitions. The site-specific interaction at the heritage space mediates the body in multiple ways. Such curated bodily movement acts as a narration that imbues the clothing on display with meanings.
A More Meticulous Method for Modeling Renewable Energy Storage Capacity
Authors: Ikenson Ben
Published: November 2023

Parzen window estimation technique promises greater accuracy, and profit, for wind and solar energy production
Cryogenic vacuum valve with actuation times down to 50 ms
Authors: Klimes J. W. , Kanika  , Krishnan A. , Reich B. , Anjum K. K. , Baus P. , Birkl G. , Quint W. , Schott W. , Vogel M.
Published: November 2023

We have conceived, built, and operated a cryogenic vacuum valve with opening and closing times as short as 50 ms that can be used in strong magnetic fields and across a broad range of duty cycles. It is used to seal a cryogenic Penning trap at liquid-helium temperature for long-term storage of highly charged ions in a vacuum better than 10−15 hPa from a room-temperature ion beamline at vacuum conditions around 10−9 hPa. It will significantly improve any experiment where a volume at the most extreme vacuum conditions must be temporarily connected to a less demanding vacuum during repeated experimental cycles. We describe the design of this valve and show measurements that characterize its main features.
Spatially resolved readout of a Fabry–Perot ultrasound sensor interrogated through a multimode optical fiber using wavefront shaping
Authors: Keenlyside Benjamin , Marques Dylan , Redgewell Nathaniel , Cherkashin Maxim , Zhang Edward , Beard Paul , Guggenheim James
Published: November 2023

The spatially resolved interrogation of a Fabry–Perot ultrasound sensor using a laser beam focused through a multimode fiber is demonstrated. To scan the beam across the sensor as required to read it out, optical wavefront shaping was employed to compensate for the scrambling of light in the fiber. By providing a means to map ultrasound through inexpensive, lightweight fibers, this could lead to new ultrasonic and photoacoustic imaging systems, such as endoscopes and flexible handheld probes.
Temperature dependent behavior of a kA-class superconducting flux pump with a continuous cylindrical stator
Authors: Venuturumilli S. , Francis A. C. , Pantoja A. E. , Taylor R. W. , Brooks J. M. , Moseley D. A. , Badcock R. A. , Bumby C. W.
Published: November 2023

A high temperature superconducting (HTS) dynamo is a type of device known as a “flux pump” that can inject DC into a closed superconducting circuit. Here, we report experimental results from a variable-temperature dynamo-type HTS flux pump operated within a cryo-cooled chamber. This device employs a “continuous stator” topology, whereby an HTS “coated conductor” is wrapped to form a cylinder around a mechanical rotor such that applied flux from the rotor magnet must always penetrate the stator. This leads to a high current device that can inject >1 kA into a series-connected HTS coil at 53 K. The open-circuit DC output voltage (Voc) from this HTS dynamo has been studied at stator temperatures between 35 and 95 K and attained a maxima at a temperature ∼5 K lower than the stator Tc. At lower temperatures, Voc decreases and falls to zero below ∼40 K. This non-intuitive effect is found to be due to flux-screening by critical currents flowing with the HTS stator, which increase with decreasing temperature. These shielding currents prevent flux from penetrating the HTS stator and, hence, reduce the magnitude of locally induced emf (and thus DC output) within the HTS film. A key implication of these results is that all magnetically driven HTS flux pumps should be operated at temperatures well above their flux-screening point, and this consideration must be taken into account for future designs of multi-kA class HTS flux pumps.