bluuebunny/crossref_metadata_2025 huggingface dataset:
O ESVAZIAMENTO DO DEBATE POLÍTICO DAS QUESTÕES PERTINENTES À REDISTRIBUIÇÃO E O AGRAVAMENTO DOS EFEITOS DA PANDEMIA NA VIDA DAS MULHERES
Authors: Friedrich Denise Bittencourt , Leite Lívia Maria Firmino
Published: January 2023

O tema do presente trabalho versa sobre o afastamento da política dos temas pertinentes a redistribuição, situação que acentuou os efeitos da pandemia na vida das mulheres, já que estas encontram-se, na grande maioria, na base da pirâmide social. O objetivo da pesquisa foi levantar dados para verificar se a teoria de Nancy Fraser oferece um suporte teórico para melhor compreender a política neoliberal que aderiu exclusivamente a pauta de reconhecimento, deixando de lado a redistribuição, fato que levou ao aumento da pobreza e aumentou o fosso que separa os mais ricos dos mais pobres. Desta forma, a autora acredita que a política deve retomar a pauta da forma diretas ou indiretas de redistribuição de renda, já que apenas a luta pela inclusão dos excluídos e pelo reconhecimento de grupos minoritários não deram e não darão conta de reduzir as injustiças sociais. Neste contexto, a pesquisa norteou-se pela seguinte indagação:  a pandemia do COVID 19 atingiu mais gravemente as mulheres devido a carência de políticas de redistribuição de renda que norteia a política neoliberal de reconhecimento? A conclusão que se chega, baseada nos números levantados e dados oficiais, é que sim.  Desta forma, pode-se responsabilizar a falta de uma pauta política realmente comprometida com as questões da pobreza, da redistribuição de renda e da redução de desigualdade como uma das responsáveis pelos altos índices de óbito decorrentes da COVID 19 entre as mulheres. O método utilizado foi o hipotético dedutivo, uma vez que a hipótese foi testada diante dos dados coletados.
INSTITUIÇÕES PARTICIPATIVAS E EFETIVIDADE DELIBERATIVA
Authors: Silva Rocha Wagner Tadeu , Bento Almeida Lindijane de Souza
Published: January 2023

Este artigo busca compreender a atuação do Conselho Municipal de Assistência Social do Natal/RN no período de março de 2020 a novembro de 2021, caracterizado pela instauração da pandemia da COVID-19. Investigou-se o desenho institucional pela Lei de Criação e Regimento Interno do conselho, e o processo deliberativo por meio das atas de reuniões para aferir a efetividade deliberativa sobre a política municipal de assistência social. Ademais, foram realizadas entrevistas virtuais semiestruturadas com representantes da sociedade civil e governo para entender a percepção acerca da dinâmica de funcionamento. Os resultados mostram que o desenho possui alto grau de institucionalização para o ordenamento do seu funcionamento, alto grau de representação para os segmentos adquirirem presença e médio grau de democratização, devido à concentração de poderes pelo presidente. Após forte atuação em 2020, o conselho encerrou 2021 com menor rendimento, retornando ao mesmo nível em um contexto sem pandemia.
ROTEM and Bivalirudin: The Confounding Challenges Ahead
Authors: Mujahid Omer Mohammed , Prakash Mohit , Choudhury Minati
Published: January 2023

Direct thrombin inhibitors directly bind to active sites on thrombin and exert their anticoagulant effect. Bivalirudin is used an alternative in cases of heparin-induced thrombocytopenia, heparin resistance, anaphylactic reaction to UFH, or anti-thrombin III deficiency. Here, we report a case of a 31-year-old female patient, diagnosed with recurrent chronic thromboembolic pulmonary hypertension posted for redo pulmonary thromboendarterectomy. Monitoring anticoagulation during bivalirudin therapy is sometimes confounding and challenging. Prolongation of CT on INTEM and HEPTEM has shown moderate to strong correlation with traditional laboratory tests like aPTT and HPTT (aPTT with Hepzyme). ROTEM can be a way forward for monitoring bivalirudin therapy.
Quantification of the Relationship Between the Height – Diameter of (Pinus brutia Ten), Calabrian Pine Trees in Four Different Microsites in Duhok Governorate. Kurdistan Region, Iraq
Authors: Salih Tariq K. , Abdulaziz Hayfaa M. Saaed
Published: January 2023

A sample of 120 trees was purposely selected from four different microsites (Behere, Swaratoka, Zawita, and Semel), (30 trees from each microsite) in the Duhok governorate. 100 of which were used for model calibration and the rest were used for validation of the selected regression equation. This study consisted of two main parts. In the first part  ,In the beginning, a scatter diagram was conducted for each microsite to detect the type of relationship between height and diameter at breast, which in turn will decrease the number of regression models that will be tested. Accordingly, 4 regression equations were developed for each of the four microsites separately. These models can be used to see how the ratio of height diameter in each of the studied sites is inter-correlated and which of them is the most appropriate for producing Calabrian pine trees.  In the second part, all microsites were then treated as one sample for estimating the parameters of 25 regression models using Excel and Statographic packageThe developed regression models underwent a screening process in order to find the most appropriate one to be used for the prediction of the height of Calabrian pine grown in the four mentioned microsites in Duhok governorate. Many measures of precision among them coefficient of determination, Bias%, Mean absolute error, Ohtomo’s unbiased test, Furnival Index, and AIC criterion were used for testing the performance of the developed equations in the prediction of the height. At last, the equation  was selected, as the best regression model. This equation shows that there is a linear relationship between  and a curvilinear relationship between D and H. The study showed that the height–diameter ratio was highest in Swaratoka and was the most appropriate microsite among the rest, followed by Behere, then Zawita and Semel came in last place.
Nanostructured Silver Thin Film: Using Successive Ionic Layer Adsorption and Reduction Method
Authors: Yatem Ari A. , Rammoo Mohammed S.
Published: January 2023

The Successive Ionic Layer Adsorption and Reduction (SILAR) method was utilized to produce nanostructured silver thin films on a glass substrate. Ag nanoparticles were grown using SILAR parameters such as silver nitrate (AgNO3), reduction time, reduction agent in an aqueous solution of hydrazine hydrate with various concentrations, and growth cycles. In this study, X-ray diffraction (XRD), scanning electron microscopy (SEM), and UV-visible-NIR absorption spectroscopy techniques were used to assess the produced silver thin film nanostructure. The size and spreading of the formed silver nanoparticles are observed to grow with the reducing agent and eventually saturate for constant growth cycles. As a result, the size and the distribution of the produced Ag nanoparticles grow uniformly. Higher growth cycles, however, caused Ag nanoparticles to lose their homogeneity and change into gravel-shaped particles. Therefore, silver nanoparticles that have been produced with the ideal SILAR conditions can be employed as an extremely sensitive, repeatable substrate with an exceptionally efficient factor. Moreover, the Effect of the concentration of HyH on the properties of SILAR-grown silver thin films has been extensively studied.
Employing EMG sensors in Bionic limbs based on a New Binary Trick Method
Authors: Mohammed Mohammed Guhdar , Salih Belnd Saadi , Haji Vaman Muhammed
Published: January 2023

Human muscles can be read by using electromyography (EMG) sensors, which are electrical signals generated by the muscles of human and animal bodies. This means it is possible to use electricity generated by muscles to control actuators/servo motors for any specific tasks. This could support a wide range of applications, especially for people with disabilities. One such application would be making bionic limbs based on servo motors. According to a study held by the K4D helpdesk report based on estimations that 15.3% of the world’s population has a moderate or severe disability, this proportion is likely to increase to 18-20% in conflict- affected areas (Thompson, 2017). The goal of this study is to make bionic limbs affordable by minimizing the cost while maintaining accuracy at an acceptable rate. To achieve this goal, the study proposes a new idea for using electromyography (EMG) sensors in bionic limbs, which suggests a decrease in the number of EMG sensors to decrease the cost and power consumption. Decreasing the number of EMG sensors will result in a loss of accuracy in controlling actuators (servo motors) because usually, each sensor is responsible for activating one servo motor. In normal projects, one will need at least six EMG sensors to control six servo motors. The study will use only three EMG sensors to control/activate six servo motors depending on the binary trick idea suggested by this study, which is manipulating all three input signals from EMG sensors at once and then deciding which servo motor to activate by using a supervised machine learning technique such as K-nearest neighbors (kNN).
Qualitative Assessment of Soil and Sediment Pollution with Some Heavy Metals: A Case Study of Duhok Valley in The Kurdistan Region of Iraq
Authors: Qaseem Najlaa Mohammad Ali , Khalid Maher , Al-Saffawi Abdulazeez
Published: January 2023

The current study was conducted on the valley of Duhok and the agricultural lands irrigated from it, where three sites were identified for collecting samples quarterly from soil and sediment using clean plastic bags for the purpose of measuring lead, nickel, cobalt and copper. Pollution load index (PLI), Nemerow pollution index (PIN), Potential Ecological Risk (PER) and Geo-accumulation Index (Igeo) were also calculated according to the internationally approved methods. The results indicated that most of lead, nickel and copper concentrations in soils and sediments exceeded the limits allowed by WHO, reaching annual rates (96.758, 168.746 and 29.88) , (111.25, 219.65 and 48.162) mg.kg-1, respectively. This fluctuation in concentrations was reflected in the values of the studied indicators for both soil and sediment, where 50% and 58% of the studied specimen are of the polluted grade and the remnant are of the non-polluted grade according to the PLI values. So is the case with PIN where 58% of the soil specimen and 41.6% of the sediment samples were of the severe pollution grade, while 25% and 33.3% of the specimen were of the heavy pollution grade and the remnant were slightly pollution grade. The same applies to the results of the PER index values, where 50% and 41.67% of the specimen were from the Medium ecological risk category, and the rest were from the low ecological risk category, likewise for the (Igeo) values, 100% and 96% of the soil and sediment samples were from the Weakly polluted category.
The Role of Strategic Vigilance as an Entrance to Achieving the Strategic Leadership in Saudi Universities
Authors: Bani Hani Sylvia Ismail Mohammad
Published: January 2023

The study aimed to reveal the strategic vigilance’s impact in Saudi universities through its dimensions: (competitive vigilance, technological vigilance). The descriptive analytical approach was used in this research, and the study sample included (62) faculty members in three universities (Hail University, Umm Al-Qura University, Taibah University). The necessary analytical statistics were conducted, in addition to testing the validity of the hypotheses. It was concluded that there is an essential role for strategic vigilance as an entry point to achieve strategic leadership in Saudi universities. The results of hypothesis testing also showed that there is a significant positive impact at the significance level (0.05) of competitive vigilance and technological vigilance dimensions on strategic leadership. Accordingly, the study recommended adopting the requirements of strategic vigilance and employing them in Saudi universities.
قلق الموت ما بعد الجلطة الدماغية لدى عينة من المصابين بالجلطة الدماغية في جمعية بيت لحم العربية للتأهيل والجراحة
Authors: خاروفة ميرنا ماريو , حسين علا علي
Published: January 2023

هدفت هذه الدراسة التعرف إلى مستوى قلق الموت ما بعد الجلطة الدماغية لدى عينة من المصابين بالجلطة الدماغية، والكشف عن الفروق في مستوى قلق الموت لديهم تبعا لمتغيرات الدراسة (الجنس، العمر، المستوى التعليمي، تكرار الإصابة، ووجود أقارب توفوا بجلطة دماغية). ولتحقيق أهداف الدراسة تم استخدام المنهج الوصفي التحليلي، وذلك بتطبيق مقياس قلق الموت المكون من (24) فقرة على عينة متيسرة قوامها (50) فرد المتواجدين في جميع اقسام جمعية بيت لحم العربية للتأهيل والجراحة. وأظهرت نتاـئج الدراسة أن مستوى قلق الموت لدى أفراد الدراسة جاء بدرجة متوسطة. كما أشارت النتائج إلى عدم وجود فروق ذات دلالة إحصائية عند مستوى الدلالة (≤0.05) في مستوى قلق الموت ما بعد الجلطة الدماغية لدى المصابين بالجلطة تعزى لمتغيرات الدراسة (الجنس، العمر، المستوى التعليمي، تكرار الجلطة ووجود أقارب توفوا بجلطة دماغية). وفي ضوء هذه النتائج أوصت الدراسة تصميم برامج إرشادية وعلاجية متخصصة لخفض درجة قلق الموت لدى المرضى ما بعد الجلطة الدماغية في جمعية بيت لحم العربية للتأهيل، وذلك لتمكين المريض من تعلم آليات التعامل مع الاعراض النفسية والجسدية.
السلوك الصحي وعلاقته بالقلق الوجودي لدى عينة من طالبات الكليات الصحية خلال جائحة كورونا
Authors: الحارثي سارة مفلح شالح
Published: January 2023

هدفت الدراسة الحالية إلى التحري عن العلاقة بين السلوك الصحي والقلق الوجودي لدى طالبات الكليات الصحية خلال جائحة كورونا، اتبعت الدراسة المنهج الوصفي الارتباطي، وطبقت على عينة قوامها (300) من طالبات الكليات الصحية بكليات الطب والصيدلة والعلوم الطبية التطبيقية قسم التمريض، بجامعة شقراء، ومن الأدوات تم استخدام مقياس السلوك الصحي (إعداد الباحثة) ومقياس القلق الوجودي إعداد (سعد وآخرون 2019)، وتوصلت نتائج الدراسة إلى "وجود علاقة بين السلوك الصحي والقلق الوجودي لدى الطالبات عينة الدراسة، كما تبين وجود كما تبين وجود فروق ذات دلالة إحصائية في متوسطات درجات العينة على مقياس السلوك الصحي ومقياس القلق الوجودي، كما تبين وجود إسهام نسبي إيجابي للسلوك الصحي على القلق الوجودي لدى الطالبات عينة الدراسة، وتوصى الدراسة الحالية بتفعيل دور الجامعات في إقامة ندوات تثقيفية لطالبات كليات التمريض للتوعية بالسلوك الصحي، والعمل على رفع المستوى الثقافي لطالبات كليات التمريض، وعقد دورات تدريبية لطالبات كلية التمريض لتخفيض القلق الوجودي لديهم.
Simultaneous Bilateral Dentigerous Cysts at the Mandibular Notch with Ectopic Third Molars: A Case Report
Authors:   1 First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Japan, A Sugauchi , T Uchihashi ,   1 First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Japan, Y Yokota ,   1 First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Japan, Y Kitaoka ,   1 First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Japan, T Inubushi ,   Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Japan, Y Ogaya ,   Department of Pediatric Dentistry, Graduate School of Dentistry, Osaka University, Japan, S Tanaka ,   1 First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Japan
Published: January 2023

Dentigerous cysts usually develop in the 2nd to 4th decades of life and contain the crown of an unerupted or impacted tooth. It is commonly observed in the mandibular third molar region. Typically, this kind oflesion presents withno symptoms, is often discovered during routine radiographic examination, and presents unilaterally. We report a case of a 59-year-old woman with bilateral radiolucent lesions located at the incisula mandibulae, containing the third molars. Histology of the specimens extracted from both sides showed findings of infected dentigerous cysts. It is an unusual case with regard to the site of the cysts as well as their simultaneity and bilaterality.
Angstrom-confined electrochemical synthesis of non van der Waals 2D metal oxides
Authors: Ji Dali , Lee Yunah , Nishina Yuta , Kamiya Kazuhide , Daiyan Rahman , Wen Xinyue , Chu Dewei , Yoshimura Masamichi , Kumar Priyank , Andreeva Daria , Novoselov Kostya , Lee Gwan-Hyoung , Joshi Rakesh , Foller Tobias
Published: January 2023

Materials in 2-dimensional (2D) form show remarkable properties and unexplored scientific phenomena compared to their bulk form. Layered, van der Waals (vdW) materials have an obvious 2D structure, whereas non-vdW materials have no preference to obtain 2D form. This limits the number of currently available 2D non-vDW materials. Here, we introduce a straightforward electrochemical method utilizing the angstrom-confinement of laminar reduced graphene oxide (rGO) nanochannels to obtain a porous polycrystalline network of 2D transition metal oxides (2D-TMO), a class of non-vdW materials. During synthesis the angstrom-confinement provides a thickness limitation, forcing sub-unit cell growth of 2D-TMO with oxygen and metal vacancies. We showcase that Cr2O3, a material without significant catalytic activity for OER in bulk form, can be activated as a high-performing catalyst if synthesized in the 2D sub-unit cell form. Our approach creates a strategy for combining the high activity of 2D form and high stability and robustness of bulk form. Our accessible method for obtaining 2D-TMO holds high promise to yield exciting properties for fundamental science and applications.
Space charge governs the kinetics of metal exsolution
Authors: Weber Moritz Lukas , Šmíd Břetislav , Breuer Uwe , Rose Marc-André , Menzler Norbert H. , Dittmann Regina , Waser Rainer , Guillon Olivier , Gunkel Felix , Lenser Christian
Published: January 2023

Nanostructured composite electrode materials play a major role in the field of catalysis and electrochemistry. Self‐assembly of metallic nanoparticles on oxide supports via metal exsolution relies on the transport of reducible dopants towards the perovskite surface to provide accessible catalytic centers at the solid/gas interface. However, it is unclear if exsolution can be driven from the oxide bulk or if the process is limited to surfaces and interfaces, where strong electrostatic gradients and space charges typically control the properties of oxides. Here we reveal that the nature of the surface‐dopant interaction is the main determining factor for the exsolution kinetics of nickel in SrTi0.9Nb0.05Ni0.05O3‐ẟ and that the exsolution depth is strongly limited to the near‐surface region of the perovskite oxide. Electrostatic interaction of dopants with surface space charge regions forming upon thermal annealing result in strong surface passivation i.e. a retarded exsolution response. We furthermore demonstrate the controllability of the exsolution response via engineering of the perovskite surface chemistry. Our findings indicate that tailoring the electrostatic gradients at the perovskite surface is an essential step to improve exsolution type materials in catalytic converters.
Memory unlocks the future of biomolecular dynamics: Transformative tools to uncover physical insights accurately and efficiently
Authors: Dominic Anthony , Cao Siqin , Montoya-Castillo Andres , Huang Xuhui
Published: January 2023

Conformational changes underpin function and encode complex biomolecular mechanisms. Gaining atomic-level detail of how such changes occur has the potential to reveal these mechanisms and is of critical importance in identifying drug targets, facilitating rational drug design, and enabling bioengineering applications. While the past two decades have brought Markov State Model techniques to the point where practitioners can regularly use them to glimpse the long-time dynamics of slow conformations in complex systems, many systems are still beyond their reach. In this perspective, we discuss how memory can reduce the computational cost to predict the long-time dynamics in these complex systems by orders of magnitude and with greater accuracy and resolution than state-of-the-art Markov State Models. We illustrate how memory lies at the heart of successful and promising techniques, ranging from the Fokker-Planck and generalized Langevin equations to deep learning recurrent neural networks and generalized master equations. We delineate how these techniques work, identify insights that they can offer in biomolecular systems, and discuss their advantages and disadvantages in practical settings. We show how generalized master equations can enable the investigation of, for example, the gate-opening process in RNA polymerase II and demonstrate how our recent advances tame the deleterious influence of statistical underconvergence of the molecular dynamics simulations used to parameterize these techniques. This represents a significant leap forward that will enable our memory-based techniques to interrogate systems that are currently beyond the reach of even the best Markov State Models. We conclude by discussing some current challenges and future prospects for how exploiting memory will open the door to many exciting opportunities.
Basis for accurate protein pKa prediction with machine learning
Authors: Cai Zhitao , Liu Tengzi , Lin Qiaoling , He Jiahao , Lei Xiaowei , Luo Fangfang , Huang Yandong
Published: January 2023

pH regulates protein structures and the resulting functions in many biological processes via protonation and deprotonation of ionizable side chains where the titration equilibra is determined by pKa. To accelerate pH-dependent molecular mechanism research in life science or industrial protein and drug designs, fast and accurate pKa prediction is crucial. Here we present a theoretical pK data set PHMD549, which was successfully applied to four distinct machine learning methods, including DeepKa that was proposed in our previous work. To reach a valid comparison, EXP67S was selected as the test set. Encouragingly, DeepKa was improved significantly and outperforms other state-of-the-art methods, except for the constant-pH molecular dynamics, which was utilized to create PHMD549. More importantly, DeepKa reproduced experimental pKa orders of acidic dyads in five enzyme catalytic sites. Apart from structural proteins, DeepKa was found applicable to intrinsically disordered peptides. Further, in combination with solvent exposures, it's revealed that DeepKa offers the most accurate prediction under the challenging circumstance that hydrogen bonding or salt bridge interaction is partly compensated by desolvation for a buried side chain. Finally, our benchmark data qualify PHMD549 and EXP67S as the basis for future developments of protein pKa prediction tools driven by artificial intelligence. In addition, DeepKa built on PHMD549 has been proved an efficient protein pKa predictor and thus can be applied immediately to, for example, pKa database construction, protein design, drug discovery and so on.
Chemical limits on X-ray nanobeam studies in water
Authors: Björling Alexander , Marcal Lucas A. B. , Arán-Ais Rosa M. , Solla-Gullón Jose
Published: January 2023

Operando X-ray studies of chemical reactions have gained increasing interest lately, fuelled by the emergence of a new generation of powerful focused X-ray sources. Although it is well known that ionizing radiation causes damage to samples via radical chemistry, this effect is often overlooked in studies of working devices or catalysts where intense focused beams are used as nano-scale probes. Here, we show how an X-ray nano-beam directly causes a phase transition in Pd nanoparticles, and that a large oxidative potential must be applied to prevent the process. We present a chemical reaction-diffusion model which offers a plausible qualitative explanation of the observations, and which also suggests that prohibitive concentrations of reactive species will arise under any focused X-ray probe, calling into question the validity of these methods as applied to aqueous chemical and catalytic systems.
Fine tuning of quantum dots photocatalysts for the synthesis of tropane alkaloid skeletons
Authors: Dabbous Ali , Colson Eloïse , Chakravorty Debargha , Mouesca Jean-Marie , Lombard Christian , Caillat Sylvain , Ravanat Jean-Luc , Dubois Fabien , Dénès Fabrice , Renaud Philippe , Maurel Vincent
Published: January 2023

Several types of Quantum Dots (QDs) (CdS, CdSe and InP, as well as core-shell QDs such as type I InP-ZnS, quasi type-II CdSe-CdS and inverse type-I CdS-CdSe) were considered for generating α-aminoalkyl free radicals. The feasibility of the oxidation of the N-aryl amines and the generation of the desired radical was evidenced experimentally by quenching of the photoluminescence of the QDs and by testing a vinylation reaction using an alkenylsulfone radical trap. The QDs were tested in a radical [3+3]-annulation reaction giving access to tropane skeletons and that requires the completion of two consecutive catalytic cycles. Several QDs such as CdS core, CdSe core and inverted type I CdS-CdSe core-shell proved to be efficient photocatalysts for this reaction. Interestingly, the addition of a second shorter chain ligand to the QDs appeared to be essential to complete the second catalytic cycle and to obtain the desired bicyclic tropane derivatives. Finally, the scope of the [3+3]-annulation reaction was explored for the best performing QDs and isolated yields that compares well with classical iridium photocatalysis were obtained.
Dissent in the Sediment? – Lake sediments as archives of short- and long-range impact of anthropogenic activities in northeastern Germany
Authors: Simon Marcel Pierre , Schatz Marlene , Böhm Leonard , Papp István , Grossart Hans-Peter , Andersen Thorbjørn Joest , Bálint Miklós , Düring Rolf-Alexander
Published: January 2023

The suitability of lake sediment cores to reconstruct past inputs, regional pollution, and usage patterns of pesticides has been shown previously. Until now, no such data exist for lakes in eastern Germany. Therefore, ten sediment cores (length 1 m) of ten lakes in eastern Germany, the territory of the former German Democratic Republic (GDR), were collected and cut into 5-10 mm layers. In each layer, concentrations of trace elements (TEs) As, Cd, Cr, Cu, Ni, Pb, S, Zn, as well as of organochlorine pesticides (OCPs) were analyzed. A miniaturized solid-liquid extraction technique in conjunction with headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) was used for the latter. Of OCPs, only transformation products of dichlorodiphenyltrichloroethane (DDT) were found. Congener ratios indicate a mainly aerial input. In the lakes’ profiles, several regional features and also responses to national policies and measures are visible. Dichlorodiphenyldichloroethane (DDD) concentrations reflect the history of DDT use in the GDR. TEs show a uniform progression over time. They follow a trans-regional pattern and are indicative of activity and policy making in West Germany before 1990 instead of those in the GDR. Lake sediments proved to be suitable to archive short- and long-range impacts of anthropogenic activity. Our data can be used to complement and validate other forms of environmental pollution long-term monitoring and check for the efficiency of pollution counter measures in the past.
Competencias profesionales en perfiles digitales: especialistas en posicionamiento web
Authors: Escandell-Poveda Raquel , Papí-Gálvez Natalia , Iglesias-García Mar
Published: January 2023

La mejora de la empleabilidad es uno de los objetivos clave de las Universidades, para lo cual es imprescindible identificar las competencias de los perfiles profesionales surgidos en la era digital, como el especialista en posicionamiento web o SEO (Search Engine Optimizer). Este artículo realiza una propuesta de perfil competencial y compara el grado de importancia otorgado por empresas y profesionales de un conjunto de competencias previamente identificado. Se ha seguido un diseño exploratorio secuencial (Dexplos), en su modalidad derivativa, que combina una metodología mixta por etapas. Se parte del análisis de demanda laboral sobre SEO y se realizan 23 entrevistas a expertos. De esta fase se extraen las competencias y se crea un instrumento cuantitativo que se lanza a modo de encuesta a dos poblaciones: los negocios y las personas que trabajan en SEO. La encuesta obtuvo 340 respuestas de empresas y 311 de profesionales. Se aplican descriptivos y se comparan los grados de importancia con la prueba T de diferencias de medias para muestras independientes. Los resultados muestran que, además de demandar una combinación de competencias específicas de comunicación, marketing y tecnología, se confiere mucha importancia a las competencias genéricas, especialmente a la capacidad de actualización. Los profesionales otorgan más peso a todas ellas hasta el punto de mostrar diferencias significativas con la empresa en la mayoría de las competencias; pero se observan similitudes en el ranking de relevancia, cuestión que conduce a realizar una propuesta válida de cara a crear una oferta formativa que responda a las necesidades en la sociedad digital.
Influence of Ocular Therapies on Spherical and Cylindrical Power of the Eye: A Case Report
Authors: K Santhosh , G Harish , K Aparna
Published: January 2023

A 28-year-old female reported with diminution of vision for distant objects in both the eyes since 12 years associated with occasional symptoms of eye strain and headache while working on the computers since five years. The subject was a diagnosed case of Compound Myopic Astigmatism and the treatment was planned on the understanding of the same as Prathama Patalagatha Timira. External ocular therapies mentioned in the classics like Virechana Nasya Tarpana Pindi and eye exercises for refractive errors were administered for the subject. Oral medication Mahatriphaladi Ghrita was started after the course of Pindi. Autorefraction was done at various stages of the treatment and during follow up. A change in spherical and cylindrical power was noted and hence an effort was made to understand the relation between the ocular therapies and power of the eye.nbsp
Efficacy of Nirgundi Patra Swarasa Nasya in Suryavarta with Special Reference to Frontal Sinusitis- A Case Study
Authors: Vidhya V Andarjanam , S Naveen B , Geetha B Kumari , Ajoy Viswam , Krishnan G Namboodiri
Published: January 2023

Suryavarta is one of the Shiro Rogas mentioned by Brihatrayis. Suryavarta is produced by Pitta and Vata as per Acharya Sushruta who mentioned that it is ldquoSarvatmakam Kastatamam Vikaramrdquo. Most of its clinical features can be correlated to the features of frontal sinusitis which is also known as vacuum headache or office headache as it affects routine and day-to-day activities of the people. Nasya Siravyadha Lepas etc. are the treatment options for Suryavarta. In the present case study a 27-year-old female patient complaining of Shirashoola Nasavarodha Shiroguruthwa and frontal sinus tenderness came to the outpatient department OPD. The patient was treated with Nasya Karma with Nirgundi Patra Swarasa added with Ghrita and Saindhava for 7 days and got relief from her symptoms.nbsp
A Review on Honey Contemplating Ayurvedic Emphasis Viz-A-Viz Source and Availability
Authors: K Sandhya , Pai Satish
Published: January 2023

Background Honey is considered to be a very important nutraceutical product since time immemorial and is collected from variable sources. Ayurveda emphasized the presence of eight types of honey best known for different medicinal and food purposes. Ethnic groups practicing folk medicine often collect honey from available sources and have little knowledge about their medicinal value. At present many brands of honey are being marketed with no mentioning about their source creating confusion among doctors as well as patients regarding their therapeutic value.Aims and Objectives To decode the concepts of identification and therapeutic usage of different varieties of honey mentioned in Ayurvedic literature with the modern knowledge about apiculture.Methods Present review article focuses on types of honey available from different varieties of bees and allied insects contemplating traditional knowledge. Information about different varieties of honey produced locally was collected from various sources and was compared with Ayurvedic classical literature to understand its therapeutic effects.Results Ayurveda has recognized the types of honey based on structure of honeybees and their hives. When these are compared with the varieties of honey currently available we can find many similarities with regard to the color and properties of the honey.Conclusion Commercial beekeeping relies on the Tuduve variety as they are easy to domesticate. There is a need for further study in this field to assess the exact medicinal value of various types of commercially available honey variants for effective utilization based on indication as both food and medicine.
Conceptual Review on Sugandha Cikitsā in Āyurveda
Authors: K Kavya , Shreevathsa Dr.
Published: January 2023

yurveda is an everlasting science with absolute principles. It not only is concerned with the treatment and cure of the diseases but also aims to allay one from all kind of miseries i.e. mental physical social and spiritual. Hence yurveda is not merely a system of medicine but also deals with all the aspects of life. The strength of any medical literature lies in its applicability and implimentation. For successful implimentation of medical literature periodical survey and evaluation is higly necessary. There are many such concepts in yurveda which may be of utmost utility in fulfilling the needs of mankind but the current trend of research is not much focused on literary research. Sugandha Cikits Aroma therapy is one such treatment trend which is having its application both in mantainance of health and cure of disease. Related references of Sugandha Cikitsand Saumansaya were collected from texts of Brhatray and other related sources to analyse the effects. Sugandha dravyas that are enriched with Gandha gua when enters nsa because oftheir Sukma amp Mrudu Gua does influence both arra and Manas. Sugandha dravys are considered as saumanasya janaka because of their positive effect on manas which in turn is also due to the pleasant aromas through which it does Svstya Rakaa of swastha and Vikra Praamana of tura.
Review on Vishajanya Janapadodwamsa Vyadhi with Special Reference to Environmental Toxicity
Authors: Mohan Gajula Vinay
Published: January 2023

Environmental toxicology is a multidisciplinary science that fills a significant gap in the field of toxicology. It is concerned with both humans and other living things and thus plays a vital role in tackling public health issues. With the growing number of environmental issues there is an urgent need for health solutions. Environmental toxicity and its health hazards has been in practice since 5000 years. In the olden days when kings entered the enemy kingdom along with their military they faced the threat of being poisoned by the entities like air water land grass and cattle feed. In present days because of human activities industries pesticides chemicals and other unhealthy behaviors the environment is getting poisoned and affecting the health of not only human beings but also other living creatures of the earth and aquatic ecosystem. The present COVID-19 crisis is also a kind of environmental toxicity affecting the whole world. This paper is an attempt to review the health problems and method of purification of such environmental particulates explained in classical texts and a discussion on the adaptation of these methods for challenging problems related to environmental toxicity in the present era.
Evolution of GURVADI GUNA– understanding and application: A review
Authors: Khare Divya , V. Savanur Prasanna
Published: January 2023

Among the shat padarthas told in Ayurveda guna finds a lot of practical applications in the diagnosis and treatment of diseases. Dravya holds its identity based on the gunas present in it. Ayurveda Samhitas have detailed the panchabhautic composition of gurvadi gunas. We also find references regarding the evolution of Panchamahabhutas srushti utpatti krama their pradhana gunas specific properties and bhutantara praveshakrita gunas imbibed properties during evolution. The concept of pancheekarana explains the evolution of karya dravyas in specific physical forms with gunas imbibed during the process of evolution. Yet the concept is not elaborate and clear enough to be applied to understand a disease and treat it. Dr. Purushottam Hirlekar in his book lsquoShareeram Tattva Darshanam Naama Vaataadi Dosha Vijnanamrdquo has tried to put some light on the evolution of gunas. The concept of evolution of gunas from bhutasamyoga combination of mahabhutas explained by him appears to be more practical as a disease can be properly understood by applying this concept of evolution of a wide range of gunas from five mahabhutas. The possible application of this concept in diagnosis and treatment has been discussed with a few examples which support its practical applicability.
Voluntary Search-and-Rescue Workers’ Experiences After Witnessing Trauma in the Earthquake Field
Authors: KÖSE Ayşen
Published: January 2023

Turkey has an earthquake-prone geography, and as in Turkey, when professional resources are not sufficiently available in a community hit by a disaster, volunteer search-and-rescue workers’ help is crucial for quickly meeting disaster-area needs. However, few studies focus on volunteer search-and-rescuer’s post-traumatic reactions although trauma literature has grown regarding professional search-and-rescue teams’ post-traumatic responses. Based on this gap in the literature, this study was conducted. This qualitative study provides an in-depth understanding of secondary trauma and vicarious post-traumatic growth among 13 search-and-rescue team workers involved in disaster relief activities following the 2020 Izmir earthquake in Turkey. Data were collected through semi-structured interviews, and an interpretive phenomenological approach was used. The findings revealed that the participants suffered secondary traumatic stress symptoms, namely, hyperarousal, intrusive images, and thoughts but experienced vicarious post-traumatic growth in discovering personal strength, relating to others, appreciating life, and striving to do their job better. This study’s findings can be a source for developing psychosocial post-disaster support services and interventions for volunteers and be used to improve pre-field preparation training content for voluntary search-and-rescue teams. The findings also underlined the fact that focusing on facilitating vicarious post-traumatic growth is as crucial as overcoming voluntary search-and-rescue workers’ post-traumatic stress.
La modelización en mecánica: una estrategia para su aprendizaje
Authors: Cabral Rosetti Luis , Castillo Rosas Adriana
Published: January 2023

Con la intensión de fortalecer las estrategias de enseñanza de los profesores que dictan los cursos de Mecánica Clásica, construimos y discutimos una serie de problemas retadores para la asignatura de Dinámica dentro de la llamada Estrategia Progresiva de Modelización vinculando diferentes conocimientos de matemáticas, física y computo. Las pruebas hechas en Cursos de capacitación a profesores nos hablan de resultados satisfactorios.
Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility
Authors: Cinato Mathieu , Mardani Ismena , Miljanovic Azra , Drevinge Christina , Laudette Marion , Bollano Entela , Henricsson Marcus , Tolö Johan , Bauza Thorbrügge Marcos , Levin Max , Lindbom Malin , Arif Muhammad , Pacher Pal , Andersson Linda , Olofsson Charlotta S , Borén Jan , Levin Malin C
Published: January 2023

The adult heart develops hypertrophy to reduce ventricular wall stress and maintain cardiac function in response to an increased workload. Although pathological hypertrophy generally progresses to heart failure, physiological hypertrophy may be cardioprotective. Cardiac-specific overexpression of the lipid-droplet protein perilipin 5 (Plin5) promotes cardiac hypertrophy, but it is unclear whether this response is beneficial. We analyzed RNA-sequencing data from human left ventricle and showed that cardiacPLIN5expression correlates with up-regulation of cardiac contraction–related processes. To investigate how elevated cardiac Plin5 levels affect cardiac contractility, we generated mice with cardiac-specific overexpression ofPlin5(MHC-Plin5mice). These mice displayed increased left ventricular mass and cardiomyocyte size but preserved heart function. Quantitative proteomics identified sarcoplasmic/endoplasmic reticulum Ca2+ATPase 2 (SERCA2) as a Plin5-interacting protein. In situ proximity ligation assay further confirmed the Plin5/SERCA2 interaction. Live imaging showed increases in intracellular Ca2+release during contraction, Ca2+removal during relaxation, and SERCA2 function in MHC-Plin5versus WT cardiomyocytes. These results identify a role of Plin5 in improving cardiac contractility through enhanced Ca2+signaling.
IMPACT OF THE CONTINENTAL FREE TRADE AREA ON THE COMPETITIVENESS OF THE ECONOMY OF THE REPUBLIC OF COTE D'IVOIRE
Authors:   RUDN-University, N’DJAH Amoin Jocelyne-Sandra , Aidrous Irina A.Z. ,   RUDN-University
Published: January 2023

In January 2021, the African Continental Free Trade Area (AfCFTA) came into effect despite the difficult conditions of the Covid-19 pandemic. The agreement aims, in particular, at creating a single and liberalized market for goods and services and facilitating the movement of capital, people and investment across the continent. The AfCFTA is expected to have a positive impact on national competitiveness GDP levels, trade, production and welfare of African countries, for example in the Republic of Ivory Coast, additional benefits will also be mainly focused on intra-African trade. The article presents the economic factors of the Republic of Côte d'Ivoire and defines its economic potential on the African continent. Also, based on the conducted SWOT analysis, we identified the internal environment (strengths and weaknesses) and the external environment (opportunities and threats) of the participation of the Republic of Côte d'Ivoire in the African Continental Free Trade Area.
THE STUDY OF GENDER DIFFERENCES IN THE PROPENSITY FOR MANAGEMENT STYLES AMONG MANAGERS
Authors:   N.N. Zubov’s State Oceanographic Institute, Protsenko Sergey A.
Published: January 2023

The article presents a study that examines the results of a socio-psychological study of the propensity for management styles in men and women and makes several practical recommendations for managers. The study involved 227 male and female managers with different work experience (from 1 to 23 years) and age (from 24 to 63 years). Of these, 85 are men and 142 are women. All of them are heads of various departments: 85 senior managers, 83 middle managers and 59 junior managers. Based on the data, the greatest division between men and women turned out to be among middle managers. While among senior managers and junior managers, an approximate equal distribution turned out. It is also worth noting that in all groups there are more female subjects than male subjects. The psychometric method "Business Profile 6" was used to study the tendency to management styles among managers. The data were processed by the t-Student criterion. In men and women, differences in the severity of the following management styles (I. Adizes) were revealed: manufacturer, administrator, entrepreneur, integrator. Recommendations are given for planning and organizing recruitment, staff development and team formation.
USING LEGAL TOOLS TO PROTECT THE SINGLE MARKET OF THE EU AND ITS SUBJECTS IN THE CONTEXT OF THE SANCTIONS WAR AGAINST RUSSIA
Authors:   MGIMO University, Gulieva Ainur Rzagulu-Gezy
Published: January 2023

The article examines the consequences of the sanctions war declared by Western countries against Russia. The author gives a brief description of the sanctions imposed since February 2022 against individuals and legal entities of Russia. Further, the author highlights the main problematic consequences of restrictive measures negatively affecting the economy of the EU member states. Information is provided on measures taken by national governments to counter inflationary pressure. Then the author considers the proposals put forward by the European Commission aimed at overcoming the energy crisis. As a result of the study, the author concludes that the European bureaucracy in the process of combating the negative consequences of the sanctions imposed against Russia faces the interests of not only national governments, but also corporate players who seek to maximize profits against the background of the crisis.
“Mending Bridges”: English Teachers Teaching for Social Cohesion
Authors: Nojaja Vincent , Kajee Leila
Published: January 2023

This article explores English Home and First Additional Language (English HL/FAL) teachers’ insights into social cohesion and what their understandings imply for teaching the language in diverse secondary schools in South Africa. Twenty-seven years into democracy, South African society remains beset with social challenges, such as increasing inequalities, poverty, and violence indicating intolerance and a general decline of moral fibre in society. Guided by the theory of social justice in education and supported by the notion that critical pedagogy has the potential to transform society, this qualitative case study explored English teachers’ perceptions of a cohesive society, and the way they teach for such a society. This study explored whether their theoretical understanding of the concept improves teachers’ positioning of education in diverse secondary schools, to achieve the broader objectives outlined in the national curriculum, and successfully foster social change in post-apartheid South African society. Conducted through the method a qualitative exploratory case study, data were elicited through semi-structured interviews and lesson observations of seven English HL/FAL teachers from three diverse secondary schools in Merafong City, in the Gauteng Province, in South Africa. Using content analysis to analyse data, this study found that teachers perceived a cohesive society as one of solidarity, respect, peace, humanity, and equal treatment. Interestingly, some teachers could not clearly link the concept with formal education, or in fact, English teaching, something which indicated that their pedagogic knowledge is limited, thus impeding the process of improving social cohesion in society.
Challenges of Implementing the Individualized Education Plan (IEP) for Special Needs Children with Learning Disabilities: Systematic Literature Review (SLR)
Authors: Rashid Syar Meeze Mohd , Wong Mei Ti
Published: January 2023

This study identified teacher challenges in the implementation of the individualized education plan (IEP) for special educational needs (SEN) children with learning disabilities (LD). A systematic literature review (SLR) was conducted to identify and synthesize the literature on this topic. Twelve studies met the inclusion criteria and were included in the analysis. Most of the findings indicated that teachers face challenges in all three aspects of competency challenges, that is knowledge, skill, and attitude challenges. Lack of knowledge on criterion-referenced tests (f = 3; 42%) can be considered as the biggest knowledge challenge faced by teachers. The biggest skill challenge was also found in the evaluation process, with teachers being less efficient in carrying out the evaluation process (f = 4; 57%). In terms of attitude challenges, the lack of motivation (f = 4; 66%) in implementing the IEP for LD children is the most common challenge encountered by teachers. Therefore, the results of the analysis and research carried out can serve as a guide and reference for educators, the Ministry of Education (MOE), and future researchers in an effort to solve teachers’ competency challenges in the IEP implementation process. However, additional high-quality research or an empirical study should be conducted to verify the validity of the conceptual framework formed by conducting a survey study in Malaysia.