bluuebunny/crossref_metadata_2025 huggingface dataset:
Biochemical reactivity and Inhibiting studies on cyclopentane-anthraquinone based compounds as potential Vascular endothelial growth factor Inhibitors
Authors: Oyebamiji Abel K. , Akintelu Sunday A. , Akintayo Emmanuel T. , Babalola Jonathan O.
Published: June 2024

Introduction: The efficiency of heterocyclic compounds as potential vascular endothelial growth factor inhibitor has drawn the attention of scientists globally.Objective of study: this work is aimed at identifying the most proficient anticancer cyclopentane-anthraquinone based compound via density functional theory and molecular modeling analysis.Method: In this work, the inhibiting capacities of cyclopentane-anthraquinone based compounds were examined using insilico method. The optimization was carried out using density functional theory and the molecular modeling studies were executed via induce fit docking and molecular dynamics simulation methods.Result: Compound 13 among other compounds have highest binding affinity compared to 5-FU (Standard) via induce fit docking study; however, the report by binding energy, root mean square deviation and root mean square fluctuation via molecular dynamic simulation study revealed otherwise. The pharmacokinetic study on compound 13 and 5-FU was examined and reported. Conclusion: These discoveries may provide perception into developing more potent potential library of drug-like triazole-based compounds as proficient anti-diabetic agents.
A Review of Eight Cases of Odontoma in Children in a Northern Nigeria Hospital
Authors: MALAMI Abdulrahman Bala , OKOLO Chizoba Chineme , OGUCHI Chikaodi O , ABORISADE Adetayo Oluwole , JIBRIL Muhammad , ADEYEMO Yewande Isabella
Published: June 2024

Background: Odontoma is a tumour-like mass resulting from the disarray in the differentiation of dental tissues. Objective: To describe the pattern of presentation of odontomas at a paediatric dentistry clinic in northern Nigeria over 24 months and discuss the comprehensive management of two cases.
Methods: A prospective cohort study was conducted, recruiting paediatric patients suspected of having an odontoma over 24 months. Clinical records were reviewed, and data on demographics, clinical presentation, medical history, diagnostic investigations, and follow-up were collected. Two cases of odontoma were comprehensively managed and presented.
Results: Eight cases of odontoma were reported, with no gender predilection. The lesions were observed in the first and second decades of life; they affected the anterior maxillae. Compound odontomas were more prevalent than complex variants. The most common effect was the impaction of primary or permanent teeth. Two cases, involving an 11-year-old male and an 11-year-old female, were managed through surgical enucleation and orthodontic treatment.
Conclusion: Although rare, odontoma is a common cause of unerupted or displaced teeth in children. Regular comprehensive oral examinations, including radiographic screening, are crucial for early diagnosis and management of these lesions.
Periscoping Supportive Supervision and Employee Service Delivery in Public Organisations in Nigeria: The Nexus
Authors: Usulor Solomon , Agbii Christian , Chukwuemeka Emma
Published: June 2024

Employees’ service delivery isfundamental for the achievement of organizational goals, and organizations are curious to identify the factors that positively affect employees’ ability to work. Supportive supervision is a process that uses dialogue and constructive feedback to help staff, and the entire organizations to improve their performance in pursuit of the organization’s goal, for growth and developmentIt can also be described as a relationship between senior and junior member of a profession that is evaluative, extends over time, serves to enhance the skills of the junior person, and monitors the quality of the services offered by the junior person and acts as gate keeping to the profession. By employing supportive supervision, administrators can not only create a healthy work environment, but also improve and sustain the performance and satisfaction of the employees in their organization. Content analysis technique was adopt4ed as a mode of analysis. The study made some fundamental revelations and recommendations were derived from the findings of the study.
Collective bargaining as a catalyst to industrial harmony in Nigeria’s Public Service. South East Public Service in perspective
Authors: Igbokwe Chukwuma
Published: June 2024

One of the most important functions of organized labor in Nigeria is collective bargaining. Absence of it brings about industrial disharmony which affects performance. This study therefore focused on collective bargaining as a catalyst for industrial harmony in the public service in Nigeria with peculiar emphasis on South-East geopolitical zone. Two research questions and two hypotheses were raised to guide the study. The study adopted a descriptive survey method of investigation. Data obtained were analyzed using Mean index, mean, standard deviation and independent t-test. The analysis was done using Statistical Package for Social Science (SPSS) version 25. The result of the hypotheses test shows that; state governments poor response to public servants grievances fuelled industrial disharmony and that their non adherence to collective bargaining agreements disrupted industrial peace in South East public service between 2010-2022. Based on the findings of this study, the research recommended that; state governments of South East, Nigeria should through the relevant agencies maintain flow of communication with the Labour Unions, giving response to workers grievances, adhere to collective agreements and avoid communication gap. The implication is that if the recommendations of this study are implemented, there will be relative industrial harmony in the public service of South East states that will engender growth and development of the public service and the economy of the entire zone.
Placide Mumbembele. Le retour du masque Kakuungu en République Démocratique du Congo : Au-delà du geste.
Authors: Bamana Gaby
Published: June 2024

no abstract
Does Ethical Guidance Improve the Performance of Organizations? Reflections From Tanzanian Health Centers
Authors: Kinemo Stella
Published: June 2024

Effective employee performance is important for health centers in delivering health services to the communities. One of the factors to be considered in improving performance is ethical leadership behavior. There has been a growing concern about unethical behaviour in Tanzania specifically on health care. The most common unethical practices are petty corruption, theft of medicine for sale, favoritism, and bribery. This study aimed to determine whether employees of health centers were guided on ethical behavior and determine the influence of ethical guidance on the performance of employees of health centers in Morogoro municipal council, Tanzania. A cross-sectional research design was adopted. The study sample size was 72, drawn from a target population of employees of five health centers. Purposive and random sampling approaches were utilized in the sampling process. A structured questionnaire was used as a data collection technique. Descriptive and regression analysis were used to analyze the quantitative data. The findings revealed that ethical guidance had a significant effect on the performance of employees of health centers in Morogoro municipality.
Pathology of experimental Salmonella gallinarum infection in turkeys (Meleagris gallopavo)
Authors: Igwe AO , Akpan EI , Tchokote EY , Okonkwo CJ , Agada GOA , Ezema WS , Okoye JOA
Published: June 2024

The present study investigated the pathology of a local Nigerian Salmonella gallinarum strain in turkeys. Fifty white Nicholas day-old poults were randomly assigned into two groups of 25 each: A/SGI – Salmonella gallinarum infected and B/SGU – Salmonella gallinarum uninfected. At fourteen-week-old, each bird in group A/SGI turkeys was inoculated with 0.2mL of 1×108 cfu of the Salmonella gallinarum orally into the crop by oral gavage, while each bird in group B/SGU received 0.2 mL of phosphate buffered saline through the same route as placebo. They were examined at different days post-challenge. A/SGI turkeys showed inappetence, depression, and yellow-green diarrhoea. The body weights were significantly (P <0.05) lower than those of B/SGU turkeys. Mortality in A/SGI was 60%. A/SGI turkeys initially had swollen and congested visceral organs with mahogany and bronze sheen liver and spleen, followed by atrophy of the pancreas and heart with thickened pericardium. The histopathological changes were fibrinoheterophilic exudate in the hepatic parenchyma with necrosis of the hepatocytes and epithelium of the bile duct, followed at the later stage by fibrosis and vacuolar degeneration. Severe lymphoid depletion was observed in the spleen. There was marked necrosis followed by pancreatic fibrosis. The heart showed marked congestion, inflammatory oedema with fibrinoheterophilic exudate, myocardial necrosis and myocardial fibrosis. These findings suggest that initial swelling, congestion of visceral organs and distinctive coppery bronze sheen of the liver and spleen, atrophy of the heart and pancreas, and fibrinoheterophilic exudates in the liver, spleen, heart and pancreas, hepatic and pancreatic fibrosis and hepatocellular vacuolar degeneration were lesions of Fowl typhoid in turkeys observed in this study.
Establishment of a failure mode and effects analysis for high-risk breviscapine-based traditional Chinese medicine injection
Authors: Mei Yingying , Zhang Tiandong , Zuo Xu , Bu Ziyun
Published: June 2024

Purpose: To assess the failure modes and effects of clinical application of breviscapine-based traditional Chinese medicine injection  (TCMI).
Methods: 229 reports on clinical application errors, medication errors or management measures relating to breviscapine injection were  collected by searching various databases. A clinical application and safety evaluation questionnaire was formulated for use in the failure  mode and effects analysis (FMEA) of breviscapine injection. The questionnaire survey was then distributed to 100 doctoral, nursing and  pharmaceutical personnel in Xinxiang Central Hospital who were randomly chosen to participate.
Results: A total of 81 (83.5 %) valid questionnaires were retrieved. A total of 29 potential failure types, failure causes and failure effects  were identified. Mean values of all risk priority numbers (RPN) of the 29 failure modes were ranked comprehensively. The failure modes  identified as top 10 risk factors include; detailed information regarding the patient’s medical, allergy and family disease history not being provided to physicians (75.22); incorrect choice of drug manufacturer and lot number (74.95), drugs not being dispensed on the spot  (72.16); inappropriate choice of solvent (71.31); drugs not suitable for combination therapy (70.81); inappropriate choice of solvent  dosage (69.14); individual patient differences not taken into consideration (67.07); infusion rate too fast (67.00); off-label drug use (65.32); and age of the patient not taken into consideration (64.96).
Conclusion: As a risk management tool, the FMEA conducted in this study  reduces potentially dangerous clinical application of high-risk TCMI, standardizes the medication process and significantly reduces  occurrence of adverse reactions to TCMI. Future studies are required to validate these claims.
Clinical effect of suspension training and Mulligan technique in combination with celecoxib in the treatment of chronic non-specific lower back pain
Authors: Wang Cong , Zhang Guannan , Wang Jingru , Zhang Wendong , Zhang Yu , Gu Yatong
Published: June 2024

Purpose: To investigate the clinical efficacy of suspension training and Mulligan technique in combination with celecoxib in the  management of chronic lower back ache of unknown causes.
Methods: A total of 100 subjects with persistent lower back pain of unknown etiology treated in the Sports Medical Rehabilitation Center, Shijiazhuang, China from June 2019 to December 2020, were assigned at random to control and study cohorts (n = 50/group). Celecoxib (100 to 200 mg/day) was taken orally, once or twice daily by  the control cohort, while the other cohort received suspension training, Mulligan technology (once a day, 8 weeks) and celecoxib. The  treatment effect, pain and dysfunction scores, inflammatory indicators, quality of life, and complications were compared on Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI).
Results: The effect of Macnab standard in study group was significantly better  than that in control group (p < 0.05). After treatment, VAS and ODI scores in both cohorts were significantly lower than pretreatment  values, but were significantly lesser in the study cohort. Furthermore, TNF-α level, and levels of CRP and IL-6 were significantly reduced  when compared with pre-treatment levels, and were significantly lower in study cohort. The GQOL-74 scores in both groups were  significantly increased after treatment, but were significantly lower in the control cohort (p < 0.05). No significant variations were seen in  cases of complications between both cohorts.
Conclusion: The use of suspension training and Mulligan technology in combination with  celecoxib in treating persistent lower back pain of unknown cause is beneficial in reducing lower back pain, mitigating dysfunction, and  improving patients' quality of life. There is however a need for more studies to validate these findings.
Supercritical fluid carbon dioxide extract of Alpinia oxyphylla ameliorates dextran sulfate sodium-induced intestinal barrier damage in mice
Authors: Yang Fan , Tao Yongqing , Chen Chen , Zhao Wei , Wang Juan , Peng Beibei , Lv Ke , Erah Patrick O. , Zhao Hui
Published: June 2024

Purpose: Inflammation and oxidative stress are the leading causes of intestinal barrier dysfunction and a wide range of diseases. The  purpose of this study was to explore the protective effect and elucidate potential mechanisms of supercritical carbon dioxide extract from  Alpinia oxyphylla Miq. (AOE) on intestinal inflammation.
Methods: The AOE was extracted by supercritical carbon dioxide extraction and its components were determined. Cytotoxicity of the  extract (0.05 to 20μg/mL) was determined on Caco-2 cells. In vitro assessment of whether AOE protected against LPS-induced intestinal  barrier dysfunction was done on Caco-2 cells pretreated with non-cytotoxic concentrations (0.5μg/mL and 1 μg/mL) of the extract. Experimental colitis of mouse model was induced by drinking water containing 3% dextran sulfate sodium (DSS). The intestinal  permeability was assessed by TEER and fluorescein isothiocyanate conjugated dextran (FITC). Pathological evidence and possible  mechanism were verified by tissue staining and molecular methods including quantitative real-time polymerase chain reaction (qRT-PCR) and western blot.
Results: TEER and FITC testing indicated that AOE pretreatment significantly improved intestinal barrier hemostasis  (p<0.05). Furthermore, AOE pretreatment counteracted DSS-induced upregulation of pro-inflammatory cytokines and oxidative stress  (p<0.05). Lastly, two crucial signal pathways regarding hemostasis of intestinal barrier, NF-κB and NOX1-LCN2, were significantly  attenuated upon AOE pretreatment (p<0.05).
Conclusion: This study sheds lights on the protective effect of AOE for intestinal hemostasis  and supports the development of AOE-based intestinal protective agents.
Validation of UV-visible spectrophotometric method for niclosamide in different media
Authors: Al-Jarsha Hayder Yahya Mansoor , Ghareeb Mowafaq M.
Published: June 2024

Purpose: To validate a UV-visible spectrophotometric technique for evaluating niclosamide (NIC) concentration in different media across  various values of pH.
Methods: NIC was investigated using a UV-visible spectrophotometer in acidic buffer solution (ABS) of pH 1.2,  deionized water (DW), and phosphate buffer solution (PBS), pH 7.4. The characterization of NIC was done with differential scanning  calorimeter (DSC), powder X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). The UV analysis was validated for  accuracy, precision, linearity, and robustness.
Results: The DSC spectra showed a single endothermic peak at 228.43 °C (corresponding to  the melting point of NIC), while XRD and FTIR analysis confirmed the identity, crystallinity and purity of NIC. In all media, the  measured concentration of NIC was within ± 5 % of the actual value, which confirmed accuracy. The percentage relative standard  deviation values were < 1 %, reflecting the precision of the  method. The range of concentration measured was between 2 and 24 µg/mL,  and all coefficient of determination (R2 ) values were > 0.99, indicating the linearity of the established analytical method. The limit of  detection (LOD) and limit of quantification (LOQ) values were 0.122 and 0.407 µg/mL in ethanol, 0.530 and 1.766 µg/mL in ABS (pH 1.2),  0.224 and 0.747 µg/mL in DW, and 0.798 and 2.662 µg/mL in PBS, pH 7.4. The robustness was confirmed as the measured concentration  under slight changes in temperatures and wavelengths were insignificant (p > 0.05).
Conclusion: Based on the results above, the UV- visible spectrophotometric method under investigation was validated to be accurate, precise, linear, and robust in all the different media  for the determination of NIC.
BİST İMALAT SEKTÖRÜNDE YER ALAN İŞLETMELERİN FİNANSAL PERFORMANSLARININ DEĞERLENDİRİLMESİ
Authors: Yiğiter Şule Yüksel , Özkan Erdem
Published: June 2024

Finansal analiz, işletmelerin mali durumunu değerlendirmek ve gelecekteki performanslarını tahmin etmek amacıyla finansal verileri inceleyen bir yöntemdir. İşletmelerin finansal durumlarının ve performanslarının bir sunumu olan finansal tablolar işletmeler tarafından hazırlanarak işletme sahipleri ve yöneticiler, yatırımcılar, müşteriler, satıcılar, kredi verenler ve sermaye piyasası kurumları gibi birçok çıkar grubunun bilgisine sunulmaktadır. Finansal tablolar, hem şirket içindeki kişiler (örneğin yöneticiler, denetim kurulları vb.) hem de şirket dışındaki kişiler (örneğin hisse senedi yatırımcıları, bankacılar, tedarikçiler, piyasa düzenleyicileri, hükümet organları) tarafından iş ve yatırım kararı vermede kullanılan temel bilgi kaynaklarından birini oluşturur. Tabloların analizi yapıldığında, işletmelerin güçlü ve zayıf yönleri, göstermiş olduğu performans, işletmenin gelecekteki durumu, yatırımların işe yarayıp yaramadığı, rakipler karşısındaki durumu gibi pek çok soruya cevap bulunacaktır. İşletmenin finansal durumunun değerlendirilmesinde finansal tabloların analizinde kullanılan Karşılaştırmalı Tablolar Analizi, Yüzde Yöntemi ile Analiz ve Oran Analizi yöntemlerinden faydalanılmıştır. Çalışmada öncelikle finansal analiz yöntemleri hakkında teorik bilgiler verilmiştir. Daha sonra BİST’de hisseleri işlem gören kimya ilaç petrol lastik ve plastik ürünler işletmesinin 2019-2021 yılı bilanço ve gelir tablosu verileri kullanılarak finansal analiz gerçekleştirilmiştir.
MANAJEMEN GREEN INDUSTRY DAN IMPLIKASINYA TERHADAP KEAMANAN LINGKUNGAN
Authors: Styawati Ika Hijria , Risdhianto Agung , Duarte Editha Praditya , Almubaroq Hikmat Zakky , Falefi Reinpal
Published: June 2024

Objektif. Penelitian ini bertujuan untuk menjelaskan pentingnya Green industry sebagai solusi bagi tantangan lingkungan global. Penelitian ini juga berupaya untuk memahami faktor-faktor yang mempengaruhi keputusan organisasi dalam mengadopsi praktik Green industry, serta mengidentifikasi dampak positifnya
Material and Metode. Data dikumpulkan melalui studi literatur, analisis paper dan artikel di Google Scholar, serta sumber dari media resmi. Data literatur dianalisis secara naratif, fokus pada konsep manajemen Green industry, penerapannya, dan dampaknya pada keamanan lingkungan. Hasil analisis data disajikan dalam bentuk narasi untuk menggambarkan hubungan antara konsep, implementasi, dan keamanan lingkungan.
Hasil. Manajemen Green industry adalah konsep manajemen yang bertujuan mengurangi dampak negatif industri terhadap lingkungan dengan prinsip-prinsip seperti pengurangan emisi gas rumah kaca, penghematan energi, pengurangan limbah, penggunaan bahan baku yang ramah lingkungan, dan penggunaan teknologi yang ramah lingkungan. Penerapan Manajemen Green industry memiliki manfaat seperti penghematan biaya operasional dan peningkatan reputasi perusahaan. Dalam konteks global, terdapat perkembangan positif seperti kebijakan dan regulasi yang mendukung, inovasi teknologi ramah lingkungan, peningkatan kesadaran masyarakat, dan kolaborasi antar pihak. Adopsi Manajemen Green industry dapat mengurangi dampak negatif terhadap lingkungan, meningkatkan kinerja ekonomi perusahaan, dan berkontribusi pada kebijakan lingkungan yang lebih baik. Adopsi ini juga memiliki dampak positif pada kebijakan lingkungan, seperti meningkatkan daya saing perusahaan, menghemat sumber daya alam dan energi, serta mendukung pembangunan berkelanjutan.
Kesimpulan. Manajemen Green industry memiliki potensi untuk mengurangi dampak negatif industri terhadap lingkungan, meningkatkan efisiensi, dan mendukung pembangunan berkelanjutan, tetapi menghadapi tantangan seperti biaya implementasi, kurangnya sumber daya manusia terampil, dan dukungan pemangku kepentingan yang belum menerapkan praktik ramah lingkungan.
A MOBILIDADE URBANA DE ESTUDANTES QUE PROCURAM FORMAÇÃO PROFISSIONAL E TECNOLÓGICA
Authors: Magalhães de Alcântara Willian , Vitor Gobis Verges João , Maschio Fioravanti Lívia
Published: June 2024

Esta pesquisa teve o objetivo de analisar as características do deslocamento dos estudantes para o Instituto Federal de Mato Grosso - Campus Várzea Grande. A partir da identificação do perfil geral dos grupos pesquisados, dos problemas encontrados no trajeto, das desigualdades socioespaciais urbanas e dos problemas do transporte público municipal e intermunicipal, pretendeu-se evidenciar possíveis impactos para o desenvolvimento das atividades discentes no campus. A metodologia empregada foi a revisão bibliográfica, levantamento e análise de dados e aplicação de questionários com os estudantes. Como resultado, elaborou-se um diagnóstico sobre a situação da mobilidade dos estudantes do campus, especificamente sobre o transporte público, apontando suas possibilidades e limitações. Os resultados contribuem tanto para fundamentar reivindicações para melhoria dos transportes, quanto para permitir à gestão escolar melhor compreender as demandas dos estudantes e repensar o cotidiano de algumas atividades do campus.
Understanding Organ Donation Messaging: A Qualitative Inquiry
Authors: Britt Rebecca K. , Ritchart Amy A.
Published: June 2024

Promoting health communication about organ donation remains a crucial objective within Native American communities. The goals of the current study were to communicate with young adult Native Americans about the Organ Donation Willingness Model (ODWM; Horton & Horton, 1991) to gain their responses to materials from campaigns about donation strategies tailored to Native American communities. Six focus groups were conducted with a total of 31 participants. Data were analyzed using thematic analysis (Braun & Clarke, 2019, 2022) and following Smith’s guidelines (2008), which include showing deep respect for the group participants, conducting the study in a face-to-face setting, and being active listeners of the group and their cultural norms, exercising special attention towards those norms. The analysis generated four themes: (1) knowledge and transplantation support emerging from family and community factors; (2) conflicting cultural beliefs; (3) geographic opportunities for improved health care, and finally, (4) the presence of Native Americans as tokenized people in campaign messages. Future collaboration with rural communities and campaign messages could focus on approaches that emphasize communal voice, social representations theory, and clear message strategies.
Literasi Keuangan Sejak Dini Pada Anak
Authors: Nurlasera  , Julina  , Lahamid Qomariah , Zuhra Fatimah
Published: June 2024

Perkembangan dunia yang sangat kompleks saat ini menuntut anak-anak harus mulai bisa bertanggungjawab atas masa depan keuangannya. Edukasi dalam pengenalan literasi keuangan menjadi ilmu yang sangat penting diberikan kepada anak-anak sejak usia dini. Literasi keuangan bertujuan untuk memastikan bahwa anak mampu mengelola keuangannya dengan baik. Program kegiatan pengabdian masyarakat ini dilakukan bertujuan untuk memberikan pembinaan terkait literasi keuangan dan menggunakan uang yaitu membelanjakan, menabung dan berinfaq sebagai Upaya untuk peningkatan literasi keuangan kepada anak-anak di Rumah Cinta Alppind Riau “Sakinah” Pekanbaru. Metode kegiatan ini adalah dengan penyampaian materi yang interaktif dan komunikatif dengan melakukan kegiatan sosialisasi tentang edukasi finansial dan membuat kegiatan jual beli, menabung dan berinfaq kepada anak-anak. Hasil kegiatan pengabdian masyarakat ini diharapkan anak-anak dapat menambah wawasan mengenai literasi keuangan, menumbuhkan minat menabung dan berinfaq sejak dini serta mendidik anak-anak untuk lebih bujak dalam menggunakan uang.
PERANCANGAN VIDEO PANDUAN PENGGUNAAN WONDERSHARE FILMORA 12 MENGGUNAKAN BAHASA MELAYU DENGAN MODEL 4D
Authors: Bayu Syahputra  , Tony Wibowo  , Said Teguh Putra Ramadhan
Published: June 2024

Video adalah rangkaian gambar yang bergerak disertai dengan audio untuk menyampaikan sebuah informasi. Video sendiri merupakan media penyampaian informasi paling diminati saat ini. Media informasi melaui video dianggap lebih mudah dimengerti dan tidak membosankan. Dengan kemajuan teknologi yang semakin massif, banyak budaya luar yang juga masuk dan diterapkan oleh masyarakat. Akibatnya banyak budaya daerah yang mulai ditinggalkan bahkan dilupakan. Dengan tujuan untuk melestarikan bahasa daerah melayu yang semakin luntur di Kepulauan Riau, penulis menggunakan bahasa melayu sebagai bahasa pengantar pada video panduan ini. Perancangan video panduan menggunakan metode kualitatif dengan melakukan wawancara kepada kuasi ahli dan metode RnD (Research and Development) dengan model 4D (define, design, development, disseminate). Model ini adalah satu model yang digunakan untuk mengembangkan perangkat pembelajaran. Pada tahap define, penulis melakukan wawancara guna menggali informasi. Pada tahap design, penulis mengembangkan materi yang sudah didapatkan pada tahap sebelumnya menjadi skrip narasi dan papan cerita. Pada tahap develop penulis mengembangkan proses sebelumnya menjadi sebuah video yang kemudian akan melewati proses uji kelayakan dan kesesuaian oleh para ahli bahasa. Kemudian pada tahap disseminate, video yang sudah diuji disebarkan melalui platform youtube..
SISTEM PELAYANAN ADMINISTRASI KEPENDUDUKAN DESA PANDA BERBASIS WEB
Authors: Khairunnisa Khairunnisa  , Shiva Gumanti Nazwa Zania , Fifi Andriani  , Jannah Miftahul
Published: June 2024

Saat ini, sistem informasi berbasis web berkembang dengan cepat, dalam instansi pemerintah yang dekat dengan masyarakat, lingkup desa adalah salah satu penerapan pengurusan administrasi. Selama administratif dilakukan secara manual di kantor desa, seringkali ada antrian dan pengelolaan data yang buruk. Akibatnya, sistem ini dibuat untuk membantu berbagai tugas administrasi kependudukan di desa. Penelitian ini memaksimalkan seperti melampirkan file surat terverfikasi petugas, rekap surat secara otomatis dalam bentuk laporan dan arsip surat, dan memberikan pemberitahuan secara langsung ke alamat email pemohon. Analisis, desain pengembangan, implementasi, dan pemeliharaan sistem adalah semua bagian dari pengembangan sistem menggunakan metode prototype. Sistem Pelayanan Ad-ministrasi Kependududkan Berbasis Web untuk mengelola pengajuan surat adalah studi kasus Desa Panda. Hasil pengujian UAT menunjukkan bahwa 80% sistem memenuhi kebutuhan pengguna
PEMANFAATAN SAM DAN YOLOV8 UNTUK DETEKSI DAN SEGMENTATION MRI TUMOR OTAK
Authors: Ardiansyah Ardiansyah , Qodri Krisna Nuresa , Banna Dion Al , Al-Baihaqi Muhammad Zulfikhar
Published: June 2024

Perkembangan kecerdasan buatan (AI) terkhusus untuk bidang Computer Vision (CV) yang bertujuan untuk mendapatkan informasi berdasarkan data yang terdapat pada media visual seperti gambar, video, ataupun lainnnya. AI pada bidang kesehatan seperti pengenalan citra atau Deep Learning (DL) menjadi pembahasan yang sering dijadikan objek penelitian dan pengembangan. Keterbatasan di bidang kesehatan menjadi kemunculan pemanfaatan AI di bidang kesehatan sehingga mendorong penelitian DL dilakukan. Segmentation Anything Model (SAM) dan YOLOv8 merupakan algoritma baru yang diperkenalkan. Sehingga, penelitian ini bertujuan mengukur pemanfaatan SAM dan YOLOv8 untuk deteksi dan segmentasi pada data MRI Brain Tumor. Sebelum Proses training peneliti melakukan perbandingan segmentasi roboflow dan model SAM terlebih dahulu. Dataset dilabeling menggunakan Bounding Box oleh para ahli dari Hayatabad Medical Complex Peshawar. Dataset berisikan 455 glioma, 550 meningoma, 620 pituitary. Penelitian yang telah dilakukan menyimpulkan pemanfaatan SAM sangat mempermudah proses anotasi. YOLOv8 dengan task segmentasi mendapatkan hasil akurasi Box untuk semua kelas 86% presisi, 87% Recall, 89% mAP50 dan 71% mAP 50-95. Sedangkan evaluasi performa mask mendapatkan hasil 86% presisi, 87% Recall, 89% mAP50, dan 70% mAP50-95. Penelitian yang dilakukan mendapatkan model yang telah dilatih menggunakan YOLOv8n-seg mendapatkan hasil sangat baik meskipun merupakan model terkecil dari YOLOv8. Penelitian ini mendapatkan kelas tumor jenis glioma menjadi kelas dengan hasil yang terendah dikarenakan dataset yang digunakan tidak banyak. Disarankan untuk penelitian selanjutkan menggunakan data augmentasi untuk menambah penggunaan dataset setiap kelas. Sehingga memberikan hasil yang lebih baik.
RETURN AND RISK INTERDEPENDENCE BASED ON THE INDEX MOVEMENT IN STOCK MARKETS AND THEIR INFLUENCE ON THE EFFECTS OF INVESTMENT
Authors: Prdić Nedeljko
Published: June 2024

The aim of the work paper is to analyse the success of the model for predicting the movement of stock market indices, that is based on the measurement of the optimal return and risk ratio. The intention is to find out how potential investors can use the ratio of return and risk index-based model to help investment decision making. It is a time-varying interdependence that can influence the result of investment. It has been concluded that the financial success result depends on the choice of a time-sensitive algorithm. The results of the research can help investment analysts who practically conduct index valuations and time frame of investments. The contribution of the research basically reflects as a framework and guidance to potential investors for future implementations.
CHURCH SERVICES - OPPORTUNITIES AND CHALLENGES OF ECUMENISM
Authors:   Donau-Universität Krems - Fakultät für Bildung, Kunst & Architektur, Rohrbach Wolfgang
Published: June 2024

The progressive secularization of Europe has become an undeniable social fact in recent decades. The separation of state and church, religion and politics, is now widely regarded as the fundamental achievement of modern times. At the same time, however, Europe follows a tradition of Christianity that is over 1,500 years old. At the meeting of the Central Committee of the World Council of Churches (February 9-15, 2022), it was emphasized, among other things: "European churches are struggling with the influence of a secularized society on their lives and witness." Individual churches cannot solve complex problems, but together there would be more opportunities than challenges. In Montenegro, about half of the population (with higher education) sees a promising future for their country in ecumenical and cosmopolitan thinking and action. Another part of the population of Montenegro still sees nationalist structures and their political representatives as salvation and maximum independence for their country. However, in a populist way, the fact that, especially small countries, need external partnerships is ignored. It seems that the politicians in question are more concerned about their position, about which Caesar said in ancient times: "It is better to be first in a Gallic village than second in Rome". To explain ecumenism in more detail, let's use an analogy - imagine that all Christian churches are housed in one multi-story building. Each church occupies one floor. What good is it for a church on the 20th floor, for example, to only reinforce the walls and floors in its premises for stabilization, if the foundation of the entire house, including the supporting pillars (which connect several floors in the lower and upper parts) would be unstable. Many church decision-makers today see ecumenism as an opportunity for preservation, salvation and future-oriented influence on the "house" of Christian cultural heritage. It should be noted that, although an increasing part of the European population stopped participating in traditional religious practice (at least, regularly), the level of private religious beliefs remained relatively high.
THE ESTABLISHING OF ROMAN POSTAL SERVICE
Authors:   University of Kragujevac, Faculty of Law, Serbia, Vladetić Srđan
Published: June 2024

The beginnings of the postal service can be found with the Egyptians, Persians or Greeks, but nowhere did the service have such scope and such organization as it was with the ancient Romans. The conquering spirit and pragmatic character of this people was the impetus for the construction of a magnificient network of roads that was built for two basic reasons – the rapid movement of the Roman army and timely and precise communication, primarly for administrative and military needs. The paper will first point out the way of transmitting messages during the period of the republic and reexamine the possibility of the existence of a state postal service in this period, and then the reforms implemented by Augustus and their significance will be exposed.
SERVICE ACTIVITY OF TRADITIONAL CHURCHES AND RELIGIOUS COMMUNITIES IN THE REPUBLIC OF SERBIA
Authors:   University of Kragujevac, Faculty of Law, Serbia, Petrović Luka
Published: June 2024

The work deals with the area of services provided by traditional churches and religious communities, with the aim of gratification the religious needs of citizens. Commonly called religious organizations, churches and religious communities represent a specific type of social organizations that have a distinct influence on social events. By analyzing the regulations governing the activities and treatment of churches and religious communities, we come to the conclusion that the mentioned organizations perform worship services, religious rites and other religious activities that satisfy the needs of their believers. The indicated activities of religious organizations can be treated as religious services, that is, services of churches and religious communities. In this labor, we first conceptually define the term "religious services", and then point out certain specificities of this type of services. We consider the issue related to settlement of services provided by religious organizations to be the most sensitive. In that domain, it is important to take into account the autonomous law of religious organizations, which regulates these issues. At the very end, we will look at the question of the educational activity of religious organizations. Educational activities are carried out in two ways: through religious educational institutions and by organizing religious classes in state and private schools. In this way, religious organizations provide religious education services to citizens. It is the state's obligation to create conditions for the functioning and realization of religious education, given that the right to religious education is included in the corpus of human and minority rights and freedoms, ie it represents a constitutive element of freedom of religion.
A Case of Pregnant Woman with Severe Mitral Regurgitation Demonstrating Left Ventricular Non-compaction
Authors: Abburu Alekhya
Published: June 2024

Left ventricular non-compaction is a rare form of cardiomyopathy. It is characterized by a thin compacted epicardial layer and a noncompacted endocardial layer with significant wall trabeculations and intertrabecular recesses that communicate with the ventricular cavity. It could be either in isolated form or coexists with other congenital heart diseases including valvular heart disease. It is associated with congestive heart failure, life threatening cardiac arrhythmia and thromboembolic complications. Adult LVNC has a prevalence of 0.01-0.27%. Diagnostic workup includes echocardiography, contrast ventriculography, and CT/MRI. Cardiac magnetic resonance imaging provides greater sensitivity and specificity, with a noncompacted to compacted myocardium ratio of > 2.3. Here we present an isolated case of Left ventricular non-compaction in a 21-year-old female due to underlying heart failure, suspected of Chronic Rheumatic Heart Disease. There is no specific treatment for LVNC, therapeutic measures are used for patient symptom relief with consideration of implantable cardioverter defibrillator and cardiac transplantation.
Effect of Three Polishing Systems on Surface Properties of Resin Composites with Different Filler Particles
Authors: Silva2 Moreira da
Published: June 2024

Objective: To evaluate the effect of rubber points and spiral-shaped wheels of three polishing systems on the surface properties (surface roughness and gloss) of four universal resin composites loaded with different filler particle systems.

Methods: Disk-shaped specimens of four resin composites loaded with different filler particles systems (n = 5 for each group): nanofilled (Z350 – Z3), suprananofilled (Estelite Omega – EO), submicron-hybrid (Brilliant Everglow – EG) and hybrid (Vitra – VI) were built up to standardized surface roughness and submitted to three polishing systems, all of them with tip and spiral-shaped wheels: Jota (JO), Ultradent (UD) and American Burrs (AB). Surface roughness (Sa parameter) was evaluated under 3D-laser confocal microscopy and gloss (gloss unit – GU) by using a glossmeter. Data were analyzed with two-way ANOVA and Tukey HSD test.

Results: Surface roughness ranged from 0.33 to 0.53 μm for rubber points and from 0.22 to 0.55 µm for spiral-shaped wheels. Regarding gloss, the ranges were 33.9 to 64.4 GU for rubber points and 29.7 to 61.5 GU for spiral-shaped wheels.

Conclusion: In general, JO and AM produced lower surface roughness and higher gloss than UD and EO and Z3, resin composites with smaller filler particles, presented better gloss than VI and EG.
Avoiding Aortic Arch Debranching with a Custom-Made Solution a Tailored Approach to Aortic Disease
Authors: Linardi Daniele
Published: June 2024

Penetrating Atherosclerotic Ulcer (PAU) is one of the acute aortic syndromes representing a medical and surgical emergency that could lead to rapid evolution and significant complications. Depending on the aortic section involved in the PAU, the treatment with endovascular prosthesis could be challenging and often requires personalized prosthesis to face anatomical peculiarities. The aortic arch could be one of the most complex locations due to the origin of supra-aortic branches and the need for previous or subsequent carotid-subclavian bypass grafting. The use of scalloped and fenestrated prostheses makes it possible to manage aortic pathology without further vascular surgery.
COVID-19 Pandemisinin Sağlık Ekonomisi Üzerine Etkisinin İncelenmesi
Authors: Kambur Elif Sena
Published: June 2024

Sağlık sektörü, insanlığın var oluşundan bu yana önemli gelişmeler yaşamış ve yaşamaya devam etmektedir. Bu gelişmeler yöntem, teknik ve teçhizatlarla ilgili önemli gelişmelerdir. Bu gelişmelerle birçok hastalığa çare bulunmuş, yeni teşhis ve tedavi yöntemleri geliştirilmiş ve geliştirilmeye devam etmektedir. Her ne kadar önemli gelişmeler kat edilmiş olsa da toplumlar farklı dönemlerde farklı bulaşıcı hastalıklarla karşı karşıya kalmış ve kalmaya devam etmektedir. Bulaşıcı hastalıkların yayılması, epidemileri bir diğer adıyla salgınları meydana getirmektedir. Epidemilerin veya salgınların sınırları aşarak uluslararası boyutlara ulaşması ve birden çok ülkeye yayılmasıyla da pandemiler meydana gelmektedir. Pandemiler, yayıldıkları ülkelerde tüm sektörleri; ekonomiyi, sosyal hayatı ve ruh sağlığını etkilemekte ve birtakım olumsuzlara neden olmaktadır. Son yıllara gelindiğinde, bu pandemilerden biri olan COVID-19 ortaya çıkmış ve COVID-19 küresel ölçekli bir sorun olarak kendini göstermiştir. Tüm dünyada COVID-19 pandemisi ile vaka ve ölüm sayıları hızla artış göstermiştir. Bu dönemde sağlık hizmetlerine başvurularda ve özellikle de yoğun bakım ve acil servislerin kullanımında yoğunluklar yaşanmıştır. Bu durumlar ise ülke sağlık sistemlerinde ciddi sorunlar yaratmış ve ülkelerin sağlık ekonomileri üzerinde ağır yükler oluşturmuştur. Bu çalışmada ise dünya tarihinde yaşanan salgınlardan kısaca bahsedilerek, COVID-19 pandemisinin dünya genelinde ve Türkiye’de sağlık ekonomisi üzerinde yarattığı etkiler derlenmiştir ve gelecekte olası pandemilerin zararlı etkilerini en aza indirebilmek amacıyla öneriler sunulmuştur.
Implementasi TQM Pada Lembaga Filantropi Sebagai Upaya Peningkatan Kepercaayan Publik
Authors: Faujiah Ani , Habibi Muhammad , Rizky Meidiana Dinda
Published: June 2024

Filantropi dapat diartikan sebagai tindakan sukarela dan kedermawanan yang dilakukan untuk kepentingan publik. Jika ditarik ke belakang, sejarah filantropi di Indonesia bermula dari unsur filantropi tradisional yang bersumber dari agama, terutama Kristen dan Islam. Filantropi keagamaan di Indonesia ini terkait dengan kegiatan misionaris serta dakwah. Pada tahun 2022 lalu, telah ramai diperbincangkan kasus dugaan penyelewengan dana donasi masyarakat oleh lembaga Aksi Cepat Tanggap (ACT). Dugaan penyelewengan itu diungkap majalah Tempo edisi 2 Juli 2022. ACT merupakan salah satu lembaga filantropi yang ada di Indonesia. Untuk mengembalikan citra positif pada lembaga filatropi khususnya pada lembaga Ziswaf perlu adanya perbaikan sistem yang ada salah satu upaya yang bisa dilaksanakan adalah penerapan TQM. Total Quality Manajemen System atau disingkat dengan TQM adalah sebuah manajemen kualitas yang lebih berfokus pada pelanggan dengan cara melibatkan seluruh level tingkatan karyawan dalam mengerjakan peningkatan ataupun perbaikan secara kontinyu. Dalam penelitian ini berfokus pada penerapan TQM pada lembaga filantropi (Ziswaf) dalam upaya meningkatkan kepercayaan masyarakat dengan pendekatan studi literatur.
 
Kata kunci : Filatropi, TQM  (Total Quality Manajemen), Ziswaf.
Urgency Of Career Women By Islamic Perspective
Authors: Dewi Riza Lisvi Vahlevi
Published: June 2024

Nowadays, a mother not only plays a role in taking care of the household, but also works. There are several factors that cause a mother to work, one of which is economic matters. From this, researchers want to dig deeper information about the incident. The purpose of this study was to determine the role of working housewives in improving family welfare and Islamic views on this phenomenon. This research uses descriptive qualitative methods and data collection techniques by interviewing and literature study. The results of this study are that working housewives can have an impact on the welfare of their families because they can financially support their husbands and their children's education. Even though they work they still pay attention to household matters. So, mothers do not do things that are contrary to what is in the teachings of Islam.
 
Key Words : Ibu Rumah Tangga, Kesejaheraan Keluarga, Perspektif Islam
Đánh giá đường huyết chu phẫu và các biến chứng sau phẫu thuật ở bệnh nhân đái tháo đường tại Khoa Ngoại Tổng Hợp Bệnh viện Đa khoa thành phố Cần Thơ năm 2020
Authors: Lưu Ngọc Trân , Châu Thị Lệ Ninh , Cao Thị Minh Trang , Bùi Xuân Trà
Published: June 2024

Tăng đường huyết chu phẫu làm tăng tỉ lệ biến chứng sau phẫu thuật ở bệnh nhân đái tháo đường [9], [14]. Chỉ 59% bệnh nhân nhập viện được kiểm soát đường huyết. Tại Việt Nam, chưa có nghiên cứu đánh giá mối liên quan giữa đường huyết chu phẫu và tỉ lệ biến chứng sau phẫu tại khoa ngoại tổng hợp. Mục tiêu: Đánh giá đường huyết chu phẫu. Xác định tỉ lệ các biến chứng sau phẫu thuật. Phân tích mối liên quan giữa đường huyết chu phẫu và các biến chứng sau phẫu thuật. Kết quả: Đạt mục tiêu đường huyết cao nhất trước phẫu thuật (64,2%) và thấp nhất ở ngày đầu tiên sau phẫu thuật (46,9%). Phẫu thuật lớn và chương trình có tỉ lệ đạt mục tiêu đường huyết cao. 66,7% bệnh nhân có biến chứng sau phẫu thuật, thường gặp nhất là viêm phổi (29,3%), nhiễm trùng vết mổ (19,5%). Đường huyết cao trước phẫu thuật tăng biến chứng hô hấp (p = 0,005) và tử vong (p = 0,043). Đường huyết đạt mục tiêu ở cả ba thời điểm có biến chứng thấp hơn 0,33 lần với p=0,031. Kết luận: Biến chứng thường gặp nhất là viêm phổi, nhiễm trùng vết mổ và suy thận cấp. Đường huyết cao trước phẫu thuật tăng biến chứng suy hô hấp và tử vong. Việc kiểm soát tốt đường huyết ở cả ba thời điểm làm giảm tỉ lệ biến chứng.
Suy tim ở bệnh nhân đái tháo đường: Từ cơ chế bệnh sinh đến cập nhật điều trị
Authors: Nguyễn Nguyên Trang
Published: June 2024

Đái tháo đường là một bệnh mạn tính, phức tạp, đòi hỏi sự chăm sóc y tế không ngừng, vừa kết hợp kiểm soát làm giảm các yếu tố nguy cơ vừa kiểm soát glucose máu. Theo ước tính, năm 2017 hiện có khoảng 451 triệu người bị đái tháo đường trên thế giới, dự kiến đến năm 2045 con số này sẽ đạt lên đến 693 triệu người. Và điều đặc biệt quan trọng là có đến khoảng một nửa số bệnh nhân (49,7%) bị đái tháo đường mà không được chẩn đoán. Các biến chứng tim mạch hiện tại vẫn là nguyên nhân hàng đầu của tỷ lệ mắc bệnh cũng như tỷ lệ tử vong ở cả bệnh nhân đái tháo đường típ 1 lẫn đái tháo đường típ 2. Bệnh nhân đái tháo đường có nhiều khả năng phát triển suy tim sung huyết hơn bệnh nhân không bị đái tháo đường (tỷ lệ mắc bệnh 30,9 so với 12,4 trường hợp trên 1.000 người/năm, tần suất mới mắc suy tim cao gấp 2,5 lần ở bệnh nhân đái tháo đường (95%, Cl 2,3-2,7). Sự khác biệt về tỷ lệ phát triển suy tim sung huyết giữa những người có và không mắc bệnh đái tháo đường lớn hơn nhiều ở các nhóm tuổi trẻ hơn. Ngoài tuổi tác và bệnh thiếu máu cơ tim, kiểm soát đường huyết kém hơn là một trong những yếu tố dự báo quan trọng về sự tiến triển suy tim sung huyết. Tình trạng suy tim ở bệnh nhân đái tháo đường, ngoài nguyên nhân mạch máu lớn là tăng huyết áp và bệnh lý động mạch do xơ vữa, thì biến chứng vi mạch là bệnh cơ tim đái tháo đường cũng chiếm vị trí quan trọng.
Phân loại bệnh lý bàn chân ở bệnh nhân đái tháo đường
Authors: Nguyễn Hải Thủy , Huỳnh Lê Thái Bão , Hoàng Thị Bích Ngọc
Published: June 2024

Đái tháo đường là một trong những bệnh lý phổ biến nhất trên toàn cầu. Bệnh cảnh này liên quan đến nhiều biến chứng do sự liên quan tiến triển ở nhiều hệ thống trên cơ thể. Bệnh lý bàn chân là một trong những biến chứng nghiêm trọng nhất ở bệnh nhân đái tháo đường. Tuy nhiên, bệnh lý bàn chân thường bị bỏ qua bởi bệnh nhân đái tháo đường và cả bác sĩ điều trị dẫn đến sự gia tăng số ca cắt cụt chi lớn trong thời gian gần đây. Nhiều phân loại khác nhau đã được đề xuất trong nhiều thập kỷ trở lại đây nhằm mô tả bệnh lý bàn chân, trong khi đó rất nhiều nhà lâm sàng chưa hề biết đến. Đặc biệt là ở các nước đang phát triển và kém phát triển, nơi mà bệnh lý này đang gia tăng một cách mạnh mẽ. Một trong những lý do chính của sự thiếu xót này là bệnh lý bàn chần thường ít được giảng dạy và thảo luận trong chương trình y khoa tiêu chuẩn. Ở một góc độ khác, bác sĩ lâm sàng quan tâm nhiều hơn đến việc tìm hiểu các phân loại khác như vậy trong các bệnh khác, trong khi bệnh lý bàn chân đái tháo đường thực sự đáng được quan tâm hơn. Tổng quan này lần đầu tiên phục vụ cho việc khảo sát các phân loại khác nhau được đề xuất, từ đó giúp các bác sĩ điều trị khác nhau tự cập nhật về bệnh lý bàn chân ở bệnh nhân đái tháo đường.