bluuebunny/crossref_metadata_2025 huggingface dataset:
Neonatal outcomes of patients with vaginal delivery after a Caesarean section
Authors: UYSAL Emre , KULHAN Nur Gözde , GÜNENC Oğuzhan
Published: December 2023

Purpose: The rates of caesarean section (CS) have been increasing in recent years in Türkiye and throughout the world. A previous CS is known to not be an absolute indication for repeat CS, and vaginal delivery (VD) (trial of labor after caesarean (TOLAC)) can occur after a CS. The aim of this study was to investigate the neonatal outcomes of TOLAC patients in Konya City Hospital.

Materials and Methods: A retrospective analysis was made of the records of all the births in Konya City Hospital between 10 August 2020 and 10 June 2022. The study included all patients with full or nearly complete cervical dilation-effacement and who had a previous CS. These patients were compared with patients who had elective CS and VD. A total of 119 patients were included in the study in 3 groups; TOLAC n:32, CS n:42, VD n:45.

Results: TOLAC patients gave birth earlier and the infant birth weight (2991.25gr), length (50.66cm) and head circumference (34.09cm) measurements were found to be significantly lower than those of the other groups. The development of any problem (icterus, respiratory distress syndrome (RDS), oxygen requirement, hypoglycemia, hypothermia) was determined at a significantly higher rate in the TOLAC (21.9%).

Conclusion: Patients with a history of CS do not have to have a repeat CS. TOLAC can be performed in appropriate cases, but care should be taken against uterine rupture, the need for emergency CS, and adverse neonatal outcomes.
Relaciones Universidad - Empresa en el Contexto Paraguayo - Oportunidad para el Sistema de Innovación
Authors: Flores-Alatorre José Francisco , Caballero García Cristina R. , Arroyo-Vázquez Mónica , Pacheco-Blanco Bélgica
Published: December 2023

El presente documento describe el desarrollo de las misiones de las Universidades como un elemento evolutivo de estas organizaciones. Siendo la tercera misional como un elemento de vinculación participativa en dimensiones sociales, empresarial, emprendedora y tecnológica. Las universidades paraguayas actualmente presentan una limitada comprensión teórica - metodológica y técnica de las actividades de las RUE a través de la tercera misión universitaria. El presente documento analiza documentalmente desde el marco normativo nacional como una posible limitante a la explotación de los conocimientos, tecnologías y capacidades instaladas de la universidad. Visualizar las posibilidades de las actividades de la tercera misión universitaria permite dinamizar las Relaciones Universidad Empresa (RUE). Los vínculos entre las relaciones universidad-empresa (RUE) necesitan un mecanismo contractual sólido. Reforzar estos mecanismos para facilitar la ejecución de estas relaciones no solo se presenta como una oportunidad para la innovación en el ámbito universitario, sino también como una posibilidad económica beneficiosa para la institución académica. En la actualidad, la Universidad Autónoma de Asunción cuenta con una Oficina de Transferencia de Resultados de Investigación (OTRI) denominada Innova Lab - UAA. Esta entidad representa una excelente oportunidad para fortalecer y fomentar el desarrollo de las conexiones entre RUE en la ciudad de Asunción. La oficina cuenta con todos los elementos técnicos necesarios para la implementación exitosa de este tipo de relaciones, incluyendo modelos contractuales y programas específicos de vinculación. Estas sinergias nos permitirán desarrollar la tercera misional de las universidades vigente a nivel internacional y colocar a la universidad como una organización a la vanguardia. La OTRI: Innova Lab - UAA es una estructura de interfaz, son oficinas acompañan el proceso de transferencia de conocimientos y de tecnología a la sociedad a través de mecanismos legales vigentes en el país o en el lugar a explotar. Permitiendo diversificar ingresos para los investigadores, inventores, estudiantes y resto de la comunidad universitaria, a través de la protección de los resultados de investigación y desarrollo que puedan contener una posibilidad de generar valor agregado. Mejorar las relaciones intra-institucionales direccionando actividades internas que permitan direccionar gestión de proyectos de: investigación, desarrollo de prototipos y actividades de innovación. A ampliarse las oportunidades de resultados de investigación con posibilidad de protección, visualizando la trasferencia tecnológica y/o de conocimientos. Las REU amplían las probabilidades de generar este tipo de oportunidades de retroalimentación al mismo sistema.
Опухоли вилочковой железы (тимомы и рака тимуса)
Authors: Барболина Т. Д. , Аллахвердиев А. К. , Владимирова Л. Ю. , Деньгина Н. В. , Козлов Н. А. , Пикин О. В.
Published: December 2023

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Хронические вирусные гепатиты
Authors: Феоктистова П. С. , Винницкая Е. В. , Нурмухаметова Е. А. , Тихонов И. Н.
Published: December 2023

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Неврологические осложнения противоопухолевой лекарственной терапии
Authors: Латипова Д. Х. , Андреев В. В. , Маслова Д. А. , Новик А. В. , Проценко С. А.
Published: December 2023

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Коррекция гепатотоксичности, индуцированной противоопухолевой терапией
Authors: Ткаченко П. Е. , Ивашкин В. Т. , Маевская М. В.
Published: December 2023

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Protective role of melatonin in ultraviolet radiation- induced oxidative stress in human skin photoaging
Authors: Suyanto Maria Veronica Putri , Widianti I Gusti Ayu
Published: December 2023

The ultraviolet radiation of the sun that reaches the earth is made up of ultraviolet A (95%) and ultraviolet B (5%). Exposure to ultraviolet radiation (UVR) is the main factor in photoaging. Chronic exposure to sunlight acts as an environmental stressor, leading to oxidative damage or stress. Oxidative damage stimulates the accumulation of free radicals, such as reactive oxygen species (ROS) or reactive nitrogen species (RNS) that are responsible for premature skin aging. Photoaged skin is characterized externally by irregular pigmentation, wrinkles, and reduced skin elasticity, and internally by the breakdown of dermal collagen and elastin. Free radicals can be scavenged and the skin can be protected from further oxidative damage by antioxidants. Melatonin is a hormone produced mainly by the pineal gland, as well as many other organs, including the skin. One of the functions of melatonin is exerted by the antioxidative melatoninergic system to prevent ultraviolet (UV)-induced skin photoaging. The aim of this review was to study the protective effect of melatonin on skin photoaging resulting from UVR exposure. The references were tracked using various databases, such as Google Scholar and PubMed with regard to publications in English for the last 5 years (2019-2023). Melatonin inhibits UVR-induced aging in multiple ways, such as protecting skin cells, binding free radicals, accelerating the activity of antioxidant enzymes, preventing increased mitochondrial membrane permeability, and assisting electron transport efficiency in the mitochondrial respiratory chain. Exogenous application of melatonin is usually by the oral route, but for localized effects on the skin, topical administration is recommended, with consideration of preparations with a better half-life and bioavailability. Understanding the protective antioxidant function of melatonin in UV-induced skin photoaging helps to optimize its application. The protective properties of melatonin against UVR-oxidative stress-induced photoaging will be further explored in this review.
AİHM KARARLARI IŞIĞINDA TERÖRLE MÜCADELEDE İDARİ KOLLUĞUN GENEL İZLEME VE TAKİP YETKİSİ VE ÖZEL HAYATIN KORUNMASI
Authors: Aydın İbrahim
Published: December 2023

Terör eylemlerinin ana hedefi cebir ve şiddet kullanarak anayasal düzeni ortadan kaldırmak ve temel hak ve hürriyetleri yok etmektir. Siyasi gerilimler, savaşlar, kitlesel göçler, iletişim, bilişim ve ulaşım teknolojilerinde yaşanan devasa değişimler yeni güvenlik tehditlerini de beraberinde getirmiştir. Sınır aşan terörist faaliyetler, organize kaçakçılık ve siber suçlar giderek yaygınlaşmıştır. Bu tehditlere karşı devletler, idari kolluğun terörle mücadelede, istihbarat toplama, izleme ve takip gibi yetkilerini artırma eğilimine girmiştir. Diğer taraftan bu durum özel hayatın korunması hakkının ihlali tartışmalarını da beraberinde getirmiştir. Ulusal mahkemelere ve Avrupa İnsan Hakları Mahkemesine ihlal başvuruları yapılmıştır. AİHM’in bu konudaki kararları hükümetler açısından da yol gösterici niteliktedir. Bu çalışmada idari kolluğa verilen genel izleme ve takip yetkisinin AİHM içtihatları açısından tartışılması amaçlanmıştır. Özel hayatın korunması ve gizliliği, ulusal güvenlik ve istihbarat kavramları hakkında açıklayıcı bilgilerin verilmesinin ardından idari kolluğa verilen genel izleme ve takip yetkileri tartışılmış ve devamında benzer uygulamalar hakkında AİHM içtihatları örneklendirilmiştir. Bu çalışmanın son kısmında bir kısım öneriler de üretilmiştir.
ПРИМЕТЫ И ПОВЕРЬЯ БУРЯТ ИРКУТСКОЙ ГУБЕРНИИ НА ОСНОВЕ ПОЛЕВЫХ ДНЕВНИКОВ М. Н. ХАНГАЛОВА
Authors:   Бурятский государственный университет имени Доржи Банзарова, Б. Б. Ангархаев
Published: December 2023

В статье представлены приметы и поверья бурят Иркутской губернии, которые были описаны в дневниках Матвей Николаевича Хангалова в конце XIX —начале XX века. У бурят существует целый комплекс представлений о приметах и поверьях. Основываясь на них, буряты верили, что смогут предугадать грядущие со-бытия. Приметы и поверья проявлялись в знаках, которые можно было увидеть практически везде. Именно эти знаки отражены в статье. Были проанализированы основные приметы и поверья бурят. Некоторые приметы имеют сопутствующую легенду для укрепления веры в примету. В статье были использованы научные работы по данной тематике и источник личного происхождения, а именно полевые дневники М. Н. Хангалова, которые хранятся в фондах Национального музея Республики Бурятия.
СЫЗРАНЬ В ПЕРИОД ЧЕХОСЛОВАЦКОГО МЯТЕЖА 1918 г.: ОСНОВНЫЕ СОБЫТИЯ, УЧАСТНИКИ, СУДЬБЫ
Authors:   Краеведческий музей городского округа Сызрань, Л. М. Куракина
Published: December 2023

В статье рассматриваются события, происходившие в г. Сызрани во время чехословацкого мятежа 1918 г. После заключения сепаратного Брестского мира Советской России с Германией и выхода России из войны вновь возник вопрос о судьбе военнопленных чехословаков. Было принято решение об их эвакуации сначала через Мурманск, затем Владивосток. Эшелоны с размещенными в них войсками чехословацкого корпуса, насчитывающего около 50 тыс. вооруженных солдат, растянулись по железной дороге практически через всю Россию: от Пензы до Владивостока. Военное руководство Антанты рассчитывало использовать эти части для свержения власти большевиков. В этом отношении они находили поддержку со стороны всех антибольшевистских сил. В горнило событий начала чехословацкого мятежа и первого периода гражданской войны попали все основные железнодорожные станции по пути следования эшелонов чехословацкого корпуса. Город Сызрань стал вторым важным пунктом после Пензы, в котором впервые в военном столкновении сошлись еще не до конца оформленные силы «красных» и «белых». Почти каждый день в период с конца мая до начала октября 1918 г. город, оказавшийся в прифронтовой зоне, переживал драматические события. Несколько раз власть менялась. Каждая такая смена власти была сопряжена с расправами над активистами, а иногда и случайными людьми. Значительное число горожан, обывателей занимали выжидательную позицию, предполагая поддержать в итоге ту власть, которая окажется сильнее. Верх взяли «красные», потеряв часть своих наиболее рьяных активистов. Судьбы многих других участников как со стороны разделявших позицию новой власти, так и особенно тех, кто поддержал «белых», навсегда изменились. В итоге произошла почти полная замена городской «верхушки»: с бывшей, происходившей из дворянской, купеческой, чиновничьей среды, на новую, пролетарскую. Среди тех, кто оказался в водовороте событий лета 1918 г. был и бывший городской архитектор Сызрани Сергей Петрович Щербаков.
Scientific Research Institute for Systems Research of the Russian Academy of Sciences
Authors: Приходько Д.И. , Мокряков А.В. , Горшков В.В.
Published: December 2023

Рассматривается особый класс приложений для операционной системы, которая предназначена для работы на нескольких режимах микропроцессора, – многоразрядные (мультиразрядные) приложения. Назначение рассматриваемых приложений – способность работать на нескольких режимах микропроцессора, который используется в экстремальных условиях окружающей среды. Указанный эффект в микропроцессоре достигается путем программного отделения поврежденных частей кристалла от целой части. Поэтому микропроцессор, режим работы которого определяется накопленными повреждениями, используется преимущественно в экстремальных условиях, к которым относятся условия космоса. В связи с этим для работы вычислительной системы в космических условиях дополнительно необходим не только специальный микропроцессор, но и особое программное обеспечение, которое способно работать на различных режимах микропроцессора. Рассмотрены базовые механизмы этого особого программного обеспечения на примере типа приложения на основе Windows исполняемого файла.

The article describes a special class of applications for operating systems: multi-bit (multi-bit) applications, which are applications that can work in several modes on a microprocessor used in extreme environmental conditions. At the technical level, by using logical separation of damaged parts of the microprocessor and changing the mode of operation of the microprocessor from more to less at the cost of reducing the accuracy of calculations, reduce the likelihood of failure of both programs and the operating system itself. There fore, for a microprocessor whose mode of operation is determined by accumulated damage, and therefore is used mainly in extreme conditions, which include space conditions. There fore, for the operation of a computer system in space conditions, not only a special microprocessor is additionally required, but also special software that is capable of operating in various modes of the microprocessor. The article discusses the basic mechanisms of this special software using the example of the type of application based on the Windows executable file.
Secuencia didáctica: una estrategia pedagógica para la formación en cultura ciudadana
Authors: Caicedo Zúñiga Schirley , Ospina Ladino Santiago
Published: December 2023

This article is the result of a Participatory Action Research that was carried out with students from grades six to eleven who assume the role of section representatives of the INEM Luis López de Mesa educational institution of the municipality of Villavicencio – Meta, taking into account who are the spokespersons chosen by their colleagues and who are assigned responsibilities in the exercise of leadership. As objectives, the researchers proposed: Identify the behaviors of the students that reflect the lack of civic culture in the institution, design a didactic sequence for the training of section representatives that contributes to the constitution of civic culture and propose the implementation of activities pedagogical activities led by section representatives in relation to the constitution of citizen culture. To collect information, three instruments were applied: analysis of documents, observation and implementation of a didactic sequence distributed in six sessions, with the last session being the planning by the participants of a Citizen Culture Day aimed at colleagues, through from which the learning acquired was evaluated and at the same time it became the action plan to address the institution’s problems. The conclusions highlight the analytical capacity of the participants to address the real situations raised, the empowerment of the role of leaders and the solutions proposed to intervene, which were characterized by creativity.
Adverse Childhood Experiences and Academic Procrastination in Emerging Adult Students: The Mediating Effect of Self-Regulation
Authors: Tahani Adhwaa Viera Mahsa , Kurniawati Kurniawati , Amaranggani Anindhita Parasdyapawitra , Rahmandani Amalia
Published: December 2023

Academic procrastination has been investigated for its relationship with low self-regulation, which is most likely influenced by adverse childhood experiences (ACEs). This quantitative study utilizes a survey and cross-sectional approach to explore the role of self-regulation in mediating the connection between ACEs and academic procrastination in emerging adult students. A convenience sample of 253 Indonesian students (Mage=20.40; SDage=1.518; Nfemale=97.1%) was obtained. The measurements included the Indonesian version of the Adverse Childhood Experiences Questionnaire (ACE-Q), the short version of the Self-Regulation Questionnaire (SSRQ), and the Academic Procrastination Scale. Statistical analysis was conducted using SPSS version 26. Out of all the participants, 74.3% reported experiencing at least one ACE. Although bivariate correlation analysis revealed a relationship between the variables, hypothesis testing through path analysis indicated that ACE did not have a direct effect on academic procrastination (B=0.871, SE=0.576, β=0.080; p 0.05), except when mediated by self-regulation (Sobel Statistic Test results: Z=4.51; p 0.001). This study highlights the importance of understanding the severity of ACEs in addressing poor self-regulation and mitigating academic procrastination among emerging adult students. Future studies may consider examining different types of ACEs, various aspects of self-regulation, and the role of sex.
The diagnostic performance of microRNAs expression levels in cellular aspirate of solitary thyroid nodule overrides that of cytology
Authors: Hussein Tawfik Ahmed T. , Hafez Emad Eldein M. Abdel , Marie Yasmin M. , Elbalshy Abdel Latif , Habashy Omnia Y.
Published: December 2023

Background: Evaluation of the diagnostic performance of estimated expression levels of microRNAs 203a, 206 and 576 in the cellular aspirate of solitary thyroid nodule (STN) in comparison to cytological examination for identification of malignant TN.
Methods: The 74 patients with STN underwent clinical and US evaluation and gave blood samples for estimation of serum levels of thyroglobulin (TG) and anti-thyroglobulin antibodies (ATG). Then, fine-needle aspiration was performed to obtain cellular aspirate for cytological examination and estimation of levels of microRNAs. The appropriate surgical procedure was undertaken and the excised specimens were sent for pathological diagnosis.
Results: Pathologically, 19 nodules had papillary thyroid carcinoma (PTC), 6 nodules had follicular carcinoma and one medullary carcinoma, while 48 nodules were benign nodules. Cytological examination diagnosed malignancy in 5 specimens, while specimens were suspicious of malignancy, 25 specimens were diagnosed as benign and 14 specimens as non-diagnostic. Serum levels of TG and ATG were significantly higher with malignancy. Expression levels of miR-203a and 206 were significantly lower, while miR-576 were significantly higher in malignant than benign aspirates. Multivariate regression analysis showed more significant ability for miR-576 level than cytological examination as screening and for miR-203a than miR-206 as diagnostic for malignant aspirate and for PTC
Conclusions: Estimation of expression levels of microRNAs in cellular aspirate of STN is feasible and accurate for detection of the malignancy. Down-expression of miR-203a and over-expression of miR-576 in tissue aspirate are more diagnostic for TC and can specify PTC cases out of other TC cases.
Pre-operative rehabilitation in reducing post operative pain
Authors: Kanagarathinam Siva Subramanian , Devakumar Satish Murugesan , Inbasekaran Anbarasu , Urabinhatti Kiran Arjun , Umesh Rohan N. , Naik R. K. Hanumantha , Thangasamy Selvaraj , Sathyanesan Jeswanth
Published: December 2023

Background: Prehabilitation is the process of improving the functional reserve of the patient. It is being a new paradigm increasingly being applied in recent days for all types of surgeries. The postoperative outcome of the patient is being affected if their functional reserve is low. It induces major complications, reduced ambulation and higher respiratory and wound related complications. One of the major factors in reducing the mobility of the patient is postoperative pain following surgery. Many studies are being done in assessing the effectiveness of prehabilitation in improving the postoperative outcome of the patients. We have done a study to evaluate the efficacy of the prehabilitation in relation to the postoperative pain score in pancreatic surgery and its outcome.
Methods: To study the effect of prehabilitation over the postoperative pain score. All patients related to benign and malignant disorders of pancreas who were subjected to surgery were taken in to study. The nutritional regimen, additional protein intake and their physical activity along with their preoperative Metabolic equivalents were taken in to study. All patients were studied for their postoperative pain score and data generated comparing their preoperative workup with postoperative pain scale.
Results: The higher metabolic equivalents had a higher significant value relating to their pain scale. The distance covered in a day also influenced the postoperative pain. About the protein intake it was shown that additional protein intake in the preoperative period has shown a significant impact on the postoperative pain scale.
Conclusions: From this little cohort group it cannot be generalised but In relation to the prehabilitory measures for pancreas related surgery in our surgical gastroenterology department. It is shown that preoperataive additional protein intake and their physical activity especially their metabolic equivalents prior to surgery had a good relation to their pain scale showing a positive correlation between them.
Study of laparoscopic drainage of liver abscess
Authors: Nadar Premalatha Andrews , Lanjewar Sunil M.
Published: December 2023

Background: Open surgical drainage was the initial treatment method for liver abscess until 1980s when image guided percutaneous aspiration in combination with antibiotic therapy became the standard of care, although open surgical drainage of liver abscess becomes necessary in some cases. Laparoscopic drainage can be considered as an alternative to surgical drainage as it reduces the morbidity and mortality and improves recovery when other treatment modalities fail. The current study is undertaken to assess the efficacy in short & long-term considering the complications, morbidity & mortality.
Methods: In this study, we will describe the procedure and clinical outcome of laparoscopy guided drainage of liver abscess.
Results: 38 cases with liver abscess were treated by laparoscopic drainage. Mean age in the study was 42 years. Mean operating time was 88 minutes. Laparoscopic drainage was uneventful in majority (78.94%). Conversion to open surgery was noted in 6 patients. No postoperative mortality was noted.
Conclusions: Laparoscopic drainage of large liver abscess is a safe treatment option. Rapid drainage & early recovery are the well-known advantages, although some limitations will require conversion for safety of the patient.
Giant peritoneal loose body: a challenging diagnosis in an asymptomatic patient
Authors: Silva André A. , Reis Rui A. , Rocha Catarina C. , Pinto-de-Sousa João
Published: December 2023

Peritoneal loose bodies are rare surgical or imaging findings. In most cases, PLBs are small in size, usually from 5 to 20 mm. Giant PLBs measuring more than 50 mm are even rarer. Only a few cases of giant PLBs have been reported. The authors report a case of a giant PLB with only mild symptoms and with no preoperative diagnosis, highlighting the importance of being aware of the characteristic findings of these lesions to establish a correct diagnosis, avoiding unnecessary surgery.
A report of a giant parathyroid adenoma
Authors: Rodrigues Ana Catarina M. , Muller Catarina , Moreira Carlos , Alves Duarte Gil , Fernandes Sara , Caires António Girão , Fernandes Jorge , Caldeira Carmo
Published: December 2023

Giant parathyroid adenoma is a rare condition characterized by the presence of an abnormally large tumor in the parathyroid gland. A 62-year-old patient diagnosed with primary hyperparathyroidism and severe nephrolithiasis leading to nephrectomy. During workup for etiologic origin of hyperparathyroidism she was found to have a giant parathyroid adenoma with 7,8x3,6x4,3 cm estimated dimensions, located posteriorly to the trachea and extending to the thoracic inlet. She was then submitted to a Kocher cervicotomy and a partial superior sternotomy. The diagnosis is initially made throw laboratorial tests that reveal the elevated calcium and PTH levels. After diagnosis, imaging studies are essential to locate the gland in order to safely remove the entire associated adenoma. Management of giant adenoma is surgical with most patients achieving cure after the gland excision.
Z dziejów polskiej przysięgi wojskowej
Authors: Ciechanowski Grzegorz
Published: December 2023

This publication analyzes the content of the Polish military oath, taking into account the historical, social and political background of the events. In four chapters, examples of this ceremony are given, starting from antiquity, through the medieval oaths of vassals for loyalty to the seniors, then the sound of the military rotas of the army of the Polish-Lithuanian Commonwealth is presented. We will find here a record of the oaths of Polish soldiers from the period of the Duchy of Warsaw, the Kingdom of Poland and national uprisings in the 19th century. These ceremonies were accompanied by symbolic elements, a special place was occupied by vexills – banners and banners, and this issue was also given attention. Source materials were widely used during the work, the author also conducted a query of Polish and foreign literature on the subject, trying to reach source materials with transcriptions characteristic of the era in which they were created. Hence the large number of quoted texts, both in terms of the content of the oath rot and the memories written down by the witnesses of these ceremonies. All chapters are illustrated with iconographic material.
Algoritms for determining the attitude position of an unmanned aerial vehicle relative to the landing platform by using computer vision
Authors: Gainutdinova T. Yu. , Novikova S. V. , Gainutdinov V. G. , Trusfus M. V. , Litvin V. M.
Published: December 2023

Algorithms for determining the attitude position of an aircraft or helicopter-type unmanned aerial vehicle relative to the landing platform with special optical marks are considered. An assessment is made of the possibility of calculating the angular position, height and distance to the landing platform in real time based on image processing by a separate on-board processor combined with a digital optical camera into a single measuring unit. The results of calculating the aircraft attitude relative to the landing platform moving along a program trajectory using computer vision algorithms are presented. Simulation of the process of recognizing optical marks on a moving platform from a moving aircraft confirmed that using a processor with a program for recognizing and identifying optical marks by using computer vision and algorithms for calculating the position of the aircraft relative to landing platforms can assuredly provide reliable information about the positioning of an unmanned aerial vehicle relative to the landing platform in real time and can be used in conjunction with other navigation aids (or independently) to ensure accurate landing of unmanned aircraft.
Wielki fakt zła i pytanie o Bożą dobroć
Authors: Hołda Miłosz
Published: December 2023

W książce Między ukryciem a jawnością. Esej z filozofii religii i teologii filozoficznej Jacek Wojtysiak podejmuje między innymi zagadnienie Bożej dobroci. Poszukuje najbardziej przekonującej odpowiedzi na pytanie o to, jak pogodzić z istnieniem Boga wielki fakt zła. Proponuje także reinterpretację tradycyjnego ujęcia Bożej dobroci poprzez rozwinięcie koncepcji Briana Daviesa. Uważam, że podjęta przez J. Wojtysiaka próba może zostać uzupełniona o kilka istotnych kwestii. W niniejszym tekście wskazuję możliwe uzupełnienia i dopowiedzenia. Zwracam uwagę na możliwe niepożądane konsekwencje płynące z niektórych proponowanych przez J. Wojtysiaka rozwiązań. Pokazuję także, w jaki sposób można by uzupełnić propozycję Autora, by możliwe było uniknięcie tych konsekwencji. Zwracam uwagę na wskazywane w dyskusjach wokół problemów zła i Bożej ukrytości niebezpieczeństwa związane z modyfikacją przypisywanego Bogu atrybutu dobroci. Dyskutuję zagadnienie „łaski kreacyjnej”, umieszczając je w nieco innym, niż to czyni Autor, kontekście. Na koniec, podejmując wyzwanie rzucone przez J. Wojtysiaka, polegające na próbie pogodzenia wielkiego faktu zła z Bożą dobrocią, przedstawiam propozycję nowego ujęcia tego zagadnienia.
Wiedza testymonialna a rozumowanie ukryte
Authors: Gałecki Sebastian
Published: December 2023

Problem ukrytości Boga staje się coraz częściej dyskutowanym tematem filozoficznym. W swoim artykule chciałbym zająć się kwestią nazwaną przez Jacka Wojtysiaka (w jego książce Między jawnością a ukryciem) (Wojtysiak 2023) „wiedzą testymonialną” i powiązać ją z Newmanowską koncepcją rozumowania implikatywnego. Odróżnienie od siebie dwóch rodzajów rozumowania — jednego spontanicznego, praktycznego, znajdującego swoje zastosowanie m.in. w obszarze wiary i moralności, oraz drugiego krytycznego, analitycznego i retrospektywnego, używanego w nauce, a także w filozofii i teologii – wydaje mi się kluczowe dla zrozumienia obserwowalnej ukrytości Boga.
Czy istnieją „rzetelnie niewierzący”? Odpowiedź teistyczna
Authors: Mordarski Ryszard
Published: December 2023

W złożonej argumentacji Jacka Wojtysiaka przeciwko argumentowi z ukrytości znajduje się przesłanka o istnieniu rzetelnie niewierzących. W niniejszym artykule przedstawiam powody, dla których klasyczny teista nie powinien akceptować tej przesłanki. W przeciwnym razie musiałby założyć, że wina za istnienie „rzetelnie niewierzących” tkwi po stronie Boga. A to prowadzi do destrukcyjnego dla teisty wniosku, że Bóg chrześcijański nie jest Bogiem wszech-przymiotów.
The Communion of Saints in the Light of Ancestor Veneration in Africa and Its Sequels on the Christian Theology of Hope
Authors: Omollo Fredrick
Published: December 2023

The article argues that the praxis of ancestor veneration in Africa is a system akin to the Christian belief in the “communion of saints.” It is a system for realizing the fullest potential of human (religious) experience. Humanness is a skill developed to become more and more human with God’s help. In this regard, well-being, or in the Christian sense, “salvation” is the fruitful accomplishment of a person’s proficiencies by sustaining beneficial relationships between earthly descendants and their ancestors. This worldview is scrutinized through the lens of the Christian doctrine of the communion of saints; thus, it is a present reality and pathway to attaining fullness of well-being. The author recognizes the tripartite Church and identifies the “exalted spiritual life,” “resurrected life,” and divine life as systematically possessed through living the doctrine of the communion of saints. Christian hope is thoroughly Christological, transcending merely natural ties.
Terapia nutricional para insuficiência renal
Authors: Abreu Ana Carolina Alves , Silva Ana Carolina Siqueira , Ribeiro Isabella Ferreira , Alves Thaís Aparecida , Chagas Mariana Monteiro
Published: December 2023

A dieta desempenha um papel crucial e determinante, conferindo benefícios significativos aos pacientes diagnosticados com Doença Renal Crônica (DRC). O rim, enquanto órgão filtrador, requer uma carga metabólica reduzida para aliviar a sobrecarga funcional renal. Portanto, ao planejar a dieta para controlar ou minimizar os sintomas da DRC, o profissional de saúde deve levar em consideração o estágio específico da doença. O planejamento dietético varia de acordo com a condição clínica atual do paciente, sendo essencial analisar as causas subjacentes da doença, incluindo possíveis comorbidades como hipertensão arterial e diabetes mellitus. Nesse sentido, o acompanhamento nutricional emerge como um elemento de extrema importância para modular a progressão da doença. O trabalho mencionado concentra-se no acompanhamento de um indivíduo em tratamento para insuficiência renal crônica, que aguarda um transplante. No contexto desse acompanhamento, o objetivo é orientar, incentivar e promover hábitos saudáveis durante o processo de tratamento. O projeto visa realizar avaliações do consumo alimentar do paciente, propondo, consequentemente, alterações nos hábitos alimentares visando aprimorar seu estado nutricional, contribuindo assim para a desaceleração da progressão da doença.
Fluorescence polarization immunoassay for the determination and screening of medicines.
Authors: Mukhametova L. I. , Eremin S. A.
Published: December 2023

Modern clinical medicine with its achievements has helped a person to get rid of many infectious and non-communicable diseases, restore health, preserve and improve the quality of life of people with chronic dis- eases. Tens of thousands of medicines are used in medical practice. However, paradoxical as it sounds, having created medicines for almost all diseases, humanity has not become healthier and the need for medicines is only growing every year. More than 20 % of people receiving medications during therapy have various complications. Therefore, the search for medicines does not stop, but only increases at the present time. Another important problem is the detecting drugs in environmental objects and food products. Most drugs that get into wastewater from pharmaceutical factories and farms, even after treatment at wastewater treatment plants, are still diagnosed in the water. The method of fluorescence polarization is extremely widespread in clinical and biomedical fields. Thanks to the introduction into laboratory diagnostics of devices capable of measuring the signal of fluorescence polarization on microplates, polarization fluorescent analysis is used not only in the traditional format: the detection of drugs in human physiological fluids, environmental objects and food, but also in high-tech screening of drugs, significantly speeding up and facilitating the process of identifying new drugs.
Features of the appearance of clinical cardiomyopathies against the background of truncating variants in the ttn gene: a review of the literature and an analysis of the appearance.
Authors: Vakhrushev Yu. A. , Andreeva S. Ye. , Gudkova A. Ya , Kovalchuk T. S. , Alekseeva D. Yu. , Khodot A. A. , Vasichkina E. S. , Yaznevich O. O. , Bortcova M. A. , Kostareva A. A.
Published: December 2023

Background. To date, the influence of genetic variants in the titin gene on the development of all types of cardiomyopathies has been proven, and this primarily applies to TTNtv, however, the high frequency of these variants in the control population (1–3 %) significantly complicates the determination of the pathogenicity of the detected variants. In addition, due to a significant population frequency (1–3 %) in patients with CMP, variants in the titin gene are often combined with causal variants in other genes, and thus can act as modifiers of the clinical course of the disease and myocardial remodeling.

Objective. To study the effect of shortening variants in the titin gene on the clinical course of cardiomyopathies in the presence of causative variants in other genes or etiological factors of the disease.

Design and methods. This article will consider three clinical cases of patients diagnosed with CMP who were treated at the Almazov National Medical Research Center. To conduct a genetic examination, next generation sequencing was used with a target cardiopanel to check 108 genes associated with the development of cardiomyopathies, as well as Sanger sequencing to exclude false positive results.

Results. During a genetic examination of the studied patients, identified genetic variants in the titin gene led to the syn- thesis of a truncated protein: in all cases, the reason for this was frameshift deletions located in exons with a PSI (Percent Spliced-In) level of 100%. According to the American College of Medical Genetics and Genomics pathogenicity classification, two genetic variants are classified as pathogenic and one is classified as probably pathogenic.

Conclusion. In these patients, we found shortening variants (frameshift deletions) in the titin gene, which acted as modifiers of myocardial remodeling.
A Topic-Based Diachronic Account of the Polysemy of the English Verb ‘Run’
Authors: Kiyama Naoki , Shibuya Yoshikata
Published: December 2023

This study discusses the polysemy and diachronic semantic frequency shifts of the English verb run using a topic model. The increase in corpus-based research in cognitive linguistics has yielded many empirical findings on various aspects of language. However, there are still areas that have not received sufficient attention. One such area is the study of word meaning in terms of related topics and social interest. In this paper, we analyze diachronic data collected from the NOW corpus (News on Web) and argue that the polysemy of run can be described in terms of topic, and that the change in the use of the meanings that this verb has can be described in terms of a change in social interest.
The Pronunciation of the Capital of Ukraine in English-Speaking Media
Authors: Bikelienė Lina
Published: December 2023

Speaker identity is one of the factors that might play a role in the realisation of sounds. Previous studies have observed that phonetic variations, alongside the formation of speaker’s identity, can index political meaning. This article aims at analysing a politically conditioned variation in rendering the name of the capital of Ukraine. Though the change from ‘Kiev’ to ‘Kyiv’ precedes the beginning of the Russian war in Ukraine, the analysis shows 24 February, 2022 has accelerated the process. Contrary to the general tendency for a language change to manifest first in the spoken mode and then proceed to writing, the findings indicate faster shift from ‘Kiev’ to ‘Kyiv’ in written English.
Tailoring International Pronunciation Activities for Hungarian Learners of English
Authors: Gyurka Noémi , Piukovics Ágnes
Published: December 2023

Pronunciation teaching is gaining more and more recognition in international contexts, however, empirical research concerning pronunciation teaching is underrepresented in the Hungarian educational context. While there are a few studies that briefly touch upon the learners’ attitudes towards pronunciation, there is limited data concerning the ways in which pronunciation could be integrated into the Hungarian English as a foreign language (EFL) classroom. Therefore, to narrow down the gap, this paper aims to investigate how international pronunciation activities could be modified when teaching Hungarian learners specifically, and how these activities could be integrated successfully into the classroom. The case study conducted involved 13 learners, who were taught by the first author of the paper as the teacher-researcher. The timeframe of the research was 11 weeks, throughout which altogether five pronunciation activities were tailored and integrated into the lessons. The results indicate that taking only methodological considerations when deciding on what feature to teach was not sufficient for successful integration. It was concluded that the learners needed to be aware of the goals of the task, its relevance to their development, and most importantly, they had to be motivated and in turn engaged, as all the factors mentioned above are prerequisites of successful integration.
Does nature work? Effects of workplace greenery on employee well-being
Authors: Popov Boris , Popov Snežana , Nastran Mojca
Published: December 2023

A significant number of studies have been conducted in order to explore the effects of greenery on various aspects of human functioning. However, little is known about how natural elements affect indicators of well-being at work, such as work burnout or work engagement. Two studies (Study 1, winter – Ljubljana, Slovenia; Study 2, spring – Novi Sad, Serbia) were performed in order to: 1) assess the effect of natural elements on work burnout and work engagement in two different seasons (winter and spring); 2) explore if gender moderates the effects of workplace greenery on work burnout and work engagement. The results from Study 1 (winter) showed that, after the exclusion of outliers from the dataset, neither indoor nor outdoor greenery had a significant effect on work engagement and work burnout. Contrary to this, in Study 2 (spring) outdoor greenery exerted a significant effect on both burnout and engagement, while indoor greenery did not. The moderating effect of gender was not clear and further studies on this topic are needed. Thus, the current research extends the existing literature on workplace greenery and demonstrates that natural elements can, to some extent, affect indicators of employee well-being, such as burnout and work engagement.
Disintegration predicts problem alcohol and drug use, quality of life, and experience in close relationships over the Big Five and HEXACO personality traits
Authors: Nedeljković Boban , Topalović Nevena
Published: December 2023

The Disintegration trait (i.e., proneness to psychotic-like experiences and behaviors) was recently proposed as the basic personality trait that supplements the space of individual differences framed by well-known Big Five and HEXACO models. In this research, we provided additional evidence of the unique contribution of Disintegration in predicting the individual differences in some outcomes whose relations with this trait are mainly unexplored. In the first study (N = 300), we employed a 20-item measure of Disintegration (DELTA-20), a short form of the Big Five Inventory (BFI-10), alcohol and drug use disorders identification tests (AUDIT, DUDIT), and Flanagan's Quality of Life Scale (QoLS). The results showed that Disintegration predicts higher levels of problem alcohol and drug use, and lower quality of life, over and above the Big Five traits, thus increasing the proportion of explained variance by 3% and 1%, respectively. In the second study (N = 537), we used a 10-item measure of Disintegration (DELTA-10), a 60-item form of HEXACO, and a Serbian version of the Modified and Revised Experiences in Close Relationship scale (SM-ECR-R). The results showed that Disintegration predicts higher levels of avoidance and anxiety in close relationships over and above HEXACO traits, with an incremental contribution in the explained variance of 2% and 11%, respectively. In sum, our findings suggested that the Disintegration trait, assessed by either the shorter or longer measure, accounts for unique variance in individual, wellbeing-related outcomes, and dyadic functioning-related outcomes. The limitations and future directions are discussed.
Family Transmission of Executive Functions: Mix of Traditional and Citizen Science Research Approach
Authors: Milovanović Ilija , Sadiković Selka , Krstić Tatjana , Stojadinović Aleksandra
Published: December 2023

The aim of this study was to examine the family transmission of executive functions deficits (working memory and inhibitory control) from parents to children, using a combination of traditional and citizen science research approaches. The final sample consisted of 110 families with two children (440 participants; 110 pairs of children, 110 fathers and 110 mothers). Children were preadolescent (6 to 10 years old; 24 pairs) or adolescent (11 to 15 years old; 86 pairs) siblings. The research results indicated that the inhibitory control of the mother is related to the inhibitory control of the younger child, and that the inhibitory control of the father is related to the inhibitory control of the older child in the family, regardless of developmental period. In the father-child relationship, it was revealed that there is a strong connection between parental and child working memory. On the other hand, there are significant interaction of mothers' working memory and age of children in the second-born child. Potential mechanisms of transmission were discussed, bearing in mind the specifics of mother's and father's involvement in raising children, as well as the potential direction of this research question towards the sphere of behavioral genetics and parenting styles.
Promoting Open Science Principles and Primenjena psihologija (Applied Psychology)
Authors: Mellor David , Pajić Dejan
Published: December 2023

At its heart, “open science” is a simple matter of sharing key parts of the research process that are traditionally not shared. These include detailed methods, protocols, and other materials needed to conduct the work: detailed analytical steps or code used for data analysis, the raw data collected during an investigation, and preliminary drafts of the manuscript. A default towards not sharing may be for many reasons, but for many years, the largest reason is that it was simply not possible to share raw data before online publication became the standard. That status quo became embedded in lab culture, and simply changing the status quo in a community as decentralized as the scientific community is always going to be a slow process. The fact that sharing more details about the process of scientific research represents a possible risk for the researcher, in a system where only statistically significant findings are publishable (Dickersin 1990; Komukai, Sugita, and Fujimoto 2023) and where others are not required to share their materials, makes it all the more challenging to move beyond the current state. By presenting activities at the Center of Open Science and efforts by the Primenjena psihologija editorial board, we appeal to our readers and fellow researchers to embrace the open science practice and use the examples provided in this special issue as a guidance for their future scientific endeavors.
Limited recovery following acellular nerve allograft reconstruction in major peripheral nerve injuries
Authors: Chi David , Johnson Anna Rose , Mackinnon Susan E.
Published: December 2023

Recent studies suggest that acellular nerve allografts (ANA) have similar efficacy as nerve autografts in certain applications of nerve surgery. However, multiple studies also demonstrate the limitations of nerve allografts, resulting in poor patient outcomes. This submission discusses a recent case series of patients who failed allograft use with subsequent histologic analyses of these allografts. Recommendations on the treatment of nerve gaps are presented, drawing from our current understanding of allograft and autograft utility in reconstruction. Factors taken into account include recipient critical nerve function, existent nerve gap, and nerve diameter.
Is a Theory of Virtue Politics Possible in Modern Nation-State Context?
Authors: FIRTIN Erol
Published: December 2023

This article calls for a possibility of virtue ethical theory of politics in contemporary political theory by locating its key sources in normative virtue ethics. First, it evaluates the growing literature on politics and virtue ethics and evaluates their promises. The following sections briefly account for two versions of virtue ethics and two key concepts, character traits and justice, to draw a framework for developing a theory of virtue politics. The last section discusses the mod- ern nation-state as the most critical setback in articulating a virtue-based political act.