bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep Learning-based Research Model of COVID-19
Authors:   Department of General Surgery, The Affiliated Bozhou Hospital of Anhui Medical University, Bozhou, Anhui Province, China, Chen Wenli , Fan Xueqin ,   Department of Nursing, The Affiliated Bozhou Hospital of Anhui Medical University, Bozhou, Anhui Province, China, Huang Shuqin ,   epartment of General Surgery, The Affiliated Bozhou Hospital of Anhui Medical University, Bozhou, Anhui Province, China, Gao Yuen ,   Department of Nursing, The Affiliated Bozhou Hospital of Anhui Medical University, Bozhou, Anhui Province, China
Published: August 2023

Coronavirus disease 2019 is an acute infectious pneumonia. The initial symptoms in infected patients are mostly fatigue, dry cough and fever, before gradually developing into more severe symptoms such as breathing difficulties. At present, the route of transmission, occurrence and development, vaccine research and development, and treatment methods of the new coronavirus pneumonia have not yet been fully clarified. Animal models are widely used to study and clarify the pathogenesis of various human diseases but there is currently no suitable animal model that can fully simulate the clinical manifestations of patients with new coronavirus pneumonia. Therefore, it is very important to establish and screen potentially suitable animal models for the study into the new coronavirus pneumonia. This article reviews the current research status of animal models of new coronavirus pneumonia, and compares the basis of different animal models for new corona pneumonia. The advantages and disadvantages of the research have sorted out the latest research progress of different types of animals in the new coronavirus pneumonia animal model, in order to provide references for the in-depth development of experimental animal models on novel coronavirus pneumonia.
Reappraising Effective Regulation in Preventing Human Organs Trafficking in Africa: Kenya and Nigeria in Perspective
Authors: Adewumi Tayewo A. , Ogunkorode Oluwayemi O.
Published: August 2023

Over the years, the issue of illegal human organ harvesting and trafficking has been an international concern. There have been so many stories of victims being promised better opportunies overseas but ended up being untraceable all over the world. The news that most of these people seeking greener pastures abroad must have fallen victim to the illegal international human harvesting and trafficking syndicates is quite alarming. The  government of the countries, their citizens to be  wary of the "too sweet to be true" job opportunities abroad and a better life abroad. United Nations' concern on this issue brought about the resolution adopted by the General Assembly at its 73rd session held on 17 December2018 on strengthening and promoting effective measures and international cooperation on organ donation and transplantation to prevent and combat trafficking in person persons for organ removal and trafficking in human organs. This article examines the law relating to organ harvesting and trafficking in Nigeria and Kenya putting into consideration the United Nations resolution. The article observes that Nigeria with its Trafficking in Person (Prohibition) Law Enforcement and Administration Act 2015 and Kenya with the Counter-Trafficking In Persons Act No. 8 of 2010 are yet to adopt the United Nations General Assembly resolution on strengthening and promoting effective measures and international cooperation on organ donation and transplanation to prevent and combat trafficking in persons for organ removal and trafficking in human organs. The article recommends total conformity with theUN resolution.
Advertising Factors Affecting Purchase Intention of Sportswear Products for Batam City People
Authors: Nurhamidah Rahel , Fahlevi Renza
Published: August 2023

Purpose – This study aims to verify whether the variables in social media advertising affect the Purchase Intention of sportswear products mediated by the Attitudes toward Advertising variable. Methodology/ approach – This study uses a causal-comparative method. The population in this study is the people of Batam City who actively use social media. The research sample is Batam City people who have watched social media advertisements. The sample collected in this study numbered 305 respondents. The data is then processed using SmartPLS software. Findings – It is found that social media advertising variables, namely Entertainment, Informativeness, Emotional Appeal, and Creativity have a significant positive effect on Attitudes toward Advertising and indirectly influence Purchase Intention mediated by Attitudes toward Advertising. Novelty/value – This study differentiates itself from the previous research not discussing sportswear products during the Covid-19 pandemic in Batam City.

Keywords: Entertainment, Informativeness, Credibility, Emotional Appeal, Creativity, Attitudes toward Advertising, Purchase Intention
Online Learning Experiences for Speaking Activities among Malaysian Undergraduate ESL Students
Authors: Saputra Syahwil , Mohd Tahir Mohd Haniff , Ariff Albakri Intan Safinas Mohd , Zaini Khazaila , Mokhtar Mazlin Mohamed , Ismail Noriah , Anisaturrahmi Anisaturrahmi , Sholihah Siti Zurriyatun
Published: August 2023

Speaking practice is crucial for ESL (English as a Second Language) students. Nevertheless, accomplishing speaking activities via online learning might be difficult for the college students at universities in Malaysia as they are non-native English speakers. There have been several studies about students' perceptions and preferences on online learning. Nonetheless, there was only a little research conducted to ascertain deep online learning perceptions and preferences of the undergraduate ESL students in Malaysia. The current article's goal was to look at ESL learners' opinions on the experiences through online connected to speaking activities at a public institution in Tanjong Malim. The mixed-research method of study was used. In this article, observation checklist, semi-structured student interview, and questionnaire were employed to get the information from the sample. The sample was then subjected to statistical analysis and standard deviation, mean score, as well as percentage to identify the Malaysian undergraduate ESL students toward online learning platforms, the difficulty that the learners encountered during the online learning, and the strategies implemented by undergraduate ESL students. Whereas the interview result was analysed by thematic analysis. The findings indicate that the use of technology for distant learning for undergraduate ESL students to improve speaking abilities was progressing well. This signifies that the students perceived that they have knowledge to use the online platforms with mean (x)= 4.07. However, several students noted that their main concern when undertaking online speaking exercises was the connection speed with mean (x)= 3.93. As a result, soliciting thoughts or ideas to boost their engagement in online speaking projects was beneficial to the pupils with mean (x)= 3.97.
Exploring Sir Walter Scott's Notions of Scottish Identity in the Context of Brexit and Scottish Independence
Authors: Alanazi Maha , Mahfouz Ahmad , Omar Abdulfattah
Published: August 2023

Numerous studies have investigated the concept of the nation and Scottish identity in the prose fiction of Sir Walter Scott. These studies have traditionally highlighted Scott’s role in reshaping public perceptions of the Scottish Highlands, their culture, and the suffering of the Highlanders under the British Empire, through his detailed knowledge of Scottish history and culture. However, it is essential to reconsider this issue in light of recent historical and political developments in Scotland after Brexit and the calls for independence by various Scottish thinkers, writers, and political leaders, aiming to join the European Union. This study revisits Scott’s concept of the Scottish nation and identity in his two texts, “The Highland Widow” and “The Two Drovers”. The findings suggest that the nationalist sentiment in Scott's writings is relevant to the social and political changes occurring in Scotland, Europe, and globally. It can be argued that much of the contemporary discourse on Scottish independence can be traced back to Scott's works, indicating a recurring historical pattern. Scott expressed concern for the loss of Scottish national identity and the right of self-determination. His texts vividly demonstrate the interconnection of past and present events, embodying both historical and contemporary perspectives.
Elliptical Humeral Head Implants in Anatomic Total Shoulder Arthroplasty
Authors: Cohn Matthew R. , Austin Luke S. , Williams Gerald R. , Abboud Joseph A.
Published: August 2023

Humeral implants for anatomic total shoulder arthroplasty and hemiarthroplasty have typically used spherical humeral heads that have a uniform diameter and radius of curvature. However, the native humeral head has a more elliptical morphology, which has spurred interest in nonspherical implant designs. Cadaveric studies indicate that the native humeral head diameter is 10% longer in the superior-inferior plane than the anterior‐posterior plane and has a radius of curvature that is approximately 8% greater. An elliptical implant that more closely replicates native anatomy may allow for more accurate coverage of the humeral resection surface with less implant overhang and risk of overstuffing. Biomechanical evidence suggests that an elliptical implant yields glenohumeral kinematics that mimic the native joint, and early clinical results are promising. As clinical research continues to emerge, it will become clearer whether encouraging cadaveric, biomechanical, and early clinical data translates to meaningful sustained improvements in patient outcomes.
ESG and Value Creation in Private Equity Investments: Analysing the Effects
Authors: Kaul Sahib
Published: August 2023

The present research evaluates the influence of Environmental, Social, and Governance (ESG) standards on the returns of private equity and explores the methods employed by private equity enterprises to incorporate ESG criteria into their investment choices. The research additionally identifies the ESG factors that are deemed most significant by private equity enterprises and scrutinises the possible advantages and disadvantages of ESG investment in the private equity sector. The present study employed a mixed-methods design, comprising a quantitative investigation of private equity returns and a qualitative exploration conducted with private equity firms. The research proposes that private equity enterprises ought to contemplate the incorporation of ESG standards into their investment assessments as a means of attaining superior returns and more effectively mitigating risk. Additional investigation is required to examine the influence of distinct ESG factors on private equity gains and to establish uniform gauges for assessing ESG accomplishments within the private equity sector.
Strategi Guru Pendidikan Agama Islam Dalam Pembentukan Kedisiplinan Siswa Di SMA Negeri 1 Jombang
Authors: Hamdy Mustain , Himami Ahmad Shofiyul , Rozaq Abd.
Published: August 2023

PAI teacher strategy is needed in the formation of student discipline character. Strategy is a pattern that is planned and determined intentionally to carry out activities or actions. The strategy includes the objectives of the activity, who is involved in the activities, the process of activities, and the means of supporting activities. The focus of this research includes: 1. How is the strategy of PAI teachers in the formation of discipline. 2. What are the inhibiting and supporting factors in the formation of discipline. The research objectives are: 1. To describe the strategy of PAI teachers in forming student discipline in SMA Negeri 1 Jombang. 2. Describing student discipline at SMA Negeri 1 Jombang. 3. Describe the factors supporting and inhibiting the formation of student discipline in SMA Negeri 1 Jombang? This study uses a qualitative method with a qualitative descriptive design that uses data collection techniques through observation, interviews and documentation. The results of the study show that: 1. The strategy used by PAI teachers in forming student discipline uses strategies inside and outside the classroom. The strategies in the classroom are using Expository, Inquiry and Reflective learning strategies and strategies outside the classroom are using exemplary methods, habituation and punishment. 2. The discipline applied at SMA Negeri 1 Jombang is time discipline, discipline to enforce and obey the rules, discipline in attitude and discipline in worship. 3. Supporting factors are the cooperation between the principal and the waka student, PAI teachers, teachers of other subjects, and a supportive family environment. While the inhibiting factor is the lack of awareness of the students themselves, many parents pay less attention to their children, especially in terms of discipline and its influence on the family and community environment.
ANALYSIS OF THE INFLUENCE OF PEDAGOGIC COMPETENCE, DIGITAL LEADERSHIP ON CAREER DEVELOPMENT
Authors: Rahmatsah Putra  , Rusyidi Abubakar  , Anwar Puteh  , Marbawi  , Ibrahim Qamarius  , Yulius Dharma
Published: August 2023

This research aims to find out the influence of pedagogical competence and digital leadership on career development's impact on the performance of East Aceh State High School teachers. The data in this study used primary data in the form of questionnaires compiled following indicators of research variables and distributed to 180 teachers of East Aceh State High School with sampling techniques conducted in the first stage of stratified random sampling then carried out with simple random sampling techniques or simple randomization of respondents in this study. Data analysis methods are used by structural analysis (SEM) and processed with the analysis of structural moments (AMOS) program. The results of the study found that there is an influence of pedagogical competence and digital leadership on career development and teacher performance, there is also digital leadership influence on the performance of High School teachers in East Aceh Regency. Furthermore, the results of this study show that pedagogical competence predominantly affects the performance of East Aceh State High School teachers.
THE EFFECT OF SOCIAL MEDIA MARKETING ON PURCHASE DECISIONS THROUGH CONSUMER BUYING INTEREST AS AN INTERVENING VARIABLE CASE STUDY OF COFFEE SHOP KOPIKUNI MEDAN
Authors: Muammar Rifqi  , Yossie Rosanty  , Elfitra Desy Surya
Published: August 2023

The culture of drinking coffee is not just thirst-quenching but can be a companion to daily activities such as gathering with friends, running a business, attending reunions, and so on. As a result, the culture of drinking coffee has become an integral part of our lifestyle, yet we continue to ignore the fact that it has caused the popularity of coffee consumption to skyrocket. This type of research uses a quantitative approach. This research was conducted at Kopikuni Medan. The sample of this research is 22 X 5 110 respondents. Test the validity and suitability of the model Loading Factor, Average Variance Extracted (AVE), and Composite Reliability. Data analysis techniques used the Structural Equation Modeling (SEM) method to test the hypotheses in this study. Purchase intention has a positive and significant effect on purchase decision Social media marketing has a positive and significant effect on purchase intention Social media marketing has a positive and significant effect on purchase decision Social media marketing has an effect on purchase decision through purchase intention. This study concludes that the variable of social media marketing that is the most significant in purchasing decisions are context and communication. Therefore, Kopikuni is advised to optimize the context and communication aspects of social media marketing by paying attention to the delivery of messages, message designs, and content posted via Kopikuni social media. Thus, Kopikuni can be remembered more by customers.
Nâng cao độ chính xác mô hình số độ cao DEM bằng mạng NƠ RON HOPFIELD với tập dữ liệu điểm độ cao bổ sung.
Authors: Nguyễn Quang Minh , Nguyễn Thị Thu Hương , Hoàng Thị Thủy , Lã Phú Hiến , Nguyễn Văn Chức , Đỗ Văn Dương
Published: August 2023

Bài báo đề cập đến việc cải thiện độ chính xác của mô hình số độ cao (Digital Elevation Model - DEM). Mặc dù, các thuật toán tái chia mẫu song tuyến, bicubic, Kriging và mô hình tăng độ phân giải bằng mạng nơ ron Hopfield (HNN) cho phép nâng cao độ chính xác cho mô hình số độ cao, đặc biệt là mô hình số độ cao từ các nguồn dữ liệu toàn cầu như SRTM, ASTER, v.v., sự tham gia của dữ liệu độ cao bổ sung cũng có thể cải thiện hơn nữa độ chính xác của mô hình số độ cao. Bài báo này đề xuất một mô hình HNN với sự tham gia của hàm hiệu chỉnh độ cao và sự thay đổi của điều kiện ràng buộc. Mô hình được thử nghiệm đánh giá tại Cao Bằng với dữ liệu DEM SRTM 30 m tại một khu vực có kích thước 1650 m × 1344 m, với 130 điểm độ cao được sử dụng để nâng cao độ chính xác và 64 điểm được sử dụng để đánh giá. Kết quả thử nghiệm cho thấy độ chính xác của DEM tăng lên tới 30% nhờ các điểm độ cao bổ sung. Kết quả cho thấy mô hình có khả năng được áp dụng trên thực tế để nâng cao độ chính xác của mô hình số độ cao DEM, đặc biệt là các DEM toàn cầu.
Comparison of brainstem auditory evoked potentials and event-related potential-300 parameters among different severity levels of depression: A study on adult patients
Authors: Gupta Anita , Singh Samir , Yadav Jai , Sharma Hanjabam , Chakravartty Anandita
Published: August 2023

Background: Depression, a serious mental health issue, linked to disruption in mood and cognitive abilities. One of the most crucial elements in the diagnosis and treatment of depression is its severity. Few researches have been conducted to determine the severity of depression on the brainstem and cognitive functioning. Therefore, this study focuses on evaluating brainstem auditory evoked potentials (BAEPs) and event-related potential (P300) parameters among depressive patients regarding severity levels (mild, moderate, and severe).

Aims and Objective: The study aims to assess BAEPs and ERP (P300) parameters among different severity levels (mild, moderate, and severe) of depressive patients and compare the results.

Materials and Methods: This cross-sectional study included 55 depressive patients divided into three groups fulfilling the diagnostic criteria of the diagnostic and statistical manual of mental disorders, fourth edition (DSM-IV) for major depressive disorder (MDD). The severity of depression was measured by the Hamilton Depression Rating Scale (HDRS). The BAEPs and ERP (P300) were recorded using NeuroStim-NS 21 and auditory oddball paradigm, respectively. Data were analyzed by one-way ANOVA followed by post hoc tests. P < 0.05 was considered statistically significant.

Results: A significant difference was found among three groups of depression severity in BAEPs, wave I for the right ear and IPL I-III for the left ear. P300 wave latency was found to be significant between mild and moderate, and also between moderate and severe groups.

Conclusion: The reported differences in BAEPs and ERP P300 latencies can be attributed to the delay in auditory processing of depressive individuals.
The replacement gilt: Current strategies for improvement of the breeding herd
Authors: Malapolska Martyna , Tuz Ryszard , Lambert Barry , Nowicki Jacek , Schwarz Tomasz
Published: August 2023

The efficiency of swine production is affected by many factors. One of the most economically important factors is gilt reproductive performance. To achieve satisfactory results in breeding, both environmental and genetic factors must be monitored and constantly improved. For many years, intensive selection in the swine industry for increased carcass muscle to fat ratio has led to deterioration in some reproductive traits (eg, less favorable development of the reproductive system in gilts, problems with fertilization, large litters but tiny piglets). In recent years, many producers have focused on increasing litter size and weaning weights of piglets in addition to an emphasis on increasing sow productive life span. In replacement gilts, the systematic evaluation of both reproductive and structural soundness is of paramount importance. The main aim of this review is to summarize the current criteria for selecting replacement gilts.
Lessons learned from managing electronic sow feeders and collecting weights of gestating sows housed on a large commercial farm
Authors: Thomas Lori , Goncalves Marcio , Vier Carine , Goodband Robert , Tokach Mike , Dritz Steve , Woodworth Jason , DeRouchey Joel
Published: August 2023

An observational study was conducted on a commercial 5600-sow farm using electronic sow feeders (ESF) to collect daily feed intake and scales to obtain sow body weights. The challenges that emerged during this study and proposed solutions may be useful for future research projects in commercial farms with ESF feeding systems. A total feed delivery per day was reported for females, regardless of how many times they may have entered the feeding station. It would be valuable to obtain records for individual feeding events to determine how many times females entered the feeding stations and if it was a feeding or non-feeding event. In this system, there was wide variation in daily sow weights because they entered the feeding station several times a day. Discrepancies in individual body weight were found to be attributed to the speed a sow moved across the scale, long scale length, and interference with the scale antenna. Possible solutions include adding panels before and after the scale, reducing scale length, and careful placement of the antenna. Nevertheless, combining the feeding of gestating sows via ESF with daily weight collection has the potential to generate valuable data sets.
Effects of pigs per feeder hole and group size on feed intake onset, growth performance, and ear and tail lesions in nursery pigs with consistent space allowance
Authors: Laskoski Fernanda , Faccin Jamil , Vier Carine , Goncalves Marcio , Orlando Uislei , Kummer Rafael , mellagi Ana , Bernardi Mari , Wentz Ivo , Bortolozzo Fernando
Published: August 2023

Objective: To determine the effects of varying the number of pigs per feeder hole and group size on feed intake onset, growth performance, and lesions in nursery pigs. Materials and methods: A total of 630 pigs were randomly assigned at weaning (mean [SD] age of 20.5 [0.9] d and weight of 5.59 [0.9] kg) to one of four treatments: 3.75, 5.00, 6.25, or 7.50 pigs per feeder hole, which was achieved by altering group size with 15, 20, 25, or 30 pigs per pen, respectively. Pigs were fed a meal diet containing 1% iron oxide dye for three days post-weaning. Rectal swabs were evaluated to assess the onset of feed intake. Pigs were weighed weekly and presence of ear and tail lesions were recorded. Results: Decreasing the number of pigs per feeder hole resulted in a decrease in onset of feed intake (P < .001). Average daily gain tended to increase linearly as the number of pigs per feeder hole decreased (P = .06). No statistically significant responses were observed for average daily feed intake and feed efficiency (P > .12). The lowest occurrence of tail lesions (P < .05) was observed in the treatment with 3.75 pigs per feeder hole. The highest incidence (P < .05) of ear lesions occurred in the treatment containing 7.50 pigs per feeder hole. Implications: Decreasing the number of pigs per feeder hole in the nursery period may result in faster onset of feed intake, improved growth performance, and reduced ear and tail lesions.
Evident similarity of porcine postparturient dysgalactia to subclinical porcine coliform mastitis
Authors: Pospischil Andreas , Bertschinger Hans
Published: August 2023

The present commentary aims to motivate future research and initiate new investigation on porcine periparturient disorders. After a short characterization of the clinical presentation of coliform mastitis, this commentary concentrates on the subclinical variant. The subclinical form of the disease resembles in most aspects what is referred to as postparturient dysgalactia syndrome of sows, and is considered highly prevalent in the field. Since the recent introduction of the ill-defined postparturient dysgalactia syndrome, experimental work has declined. Except for review articles, there is a shortage of recent publications in this area. Previously published experimental data led to a promising approach to prevent coliform mastitis by reducing the level of teat contamination by coliform bacteria. With the ongoing need to reduce antimicrobial use in food-producing animals, there is a continued need to investigate preventive strategies.
The use of oral fluid diagnostics in swine medicine
Authors: Bjustrom-Kraft Jordan , Christopher-Hennings Jane , Daly Russ , Main Rodger , Torrison Jerry , Thurn Mary , Zimmerman Jeffrey
Published: August 2023

Swine veterinarians in North America have applied oral fluid-based testing methodologies for an increasing number of systemic, respiratory, and enteric disease diagnostic applications. Since the first report of oral fluid testing in 2008, nucleic acid and antibody assays have been described in the peer-reviewed literature for many pathogens affecting swine. As evidence of the US swine industry’s growing utility of oral fluids as a diagnostic tool, the cumulative number of swine oral fluid diagnostic tests conducted at three veterinary diagnostic laboratories in the upper Midwest (Iowa State University, South Dakota State University, and University of Minnesota) has increased from approximately 21,000 tests in 2010 to nearly 370,000 tests in 2016. The objective of this review is to describe the developments in oral fluid diagnostics that have led to its widespread use and to highlight areas of concern as this technology is increasingly implemented by producers and veterinarians.
Subclinical colitis associated with moderately hemolytic Brachyspira strains
Authors: Costa Matheus , Ek Courtney , Patterson Mo , Nosach Roman , Detmer Susan , Fernando Champika , Paul-McKenzie Gabrielle , van Ravenstein Steve , Enns Cole , Loewen Matthew , Hill Janet , Harding John
Published: August 2023

Objective: Microbiological and virulence characterization of 2 moderately hemolytic Brachyspira strains. Materials and methods: Clinical isolates were obtained from diarrheic (3603-F2) and healthy (G79) pigs. Phenotypic characterization included assessment of hemolytic activity on blood agar and biochemical profiling. Genotyping was performed by sequencing the nicotinamide adenine dinucleotide oxidase (nox) gene, whole genome sequencing, and comparison to relevant Brachyspira. Pig inoculation included 4 treatment groups in 2 challenge experiments: negative control (sterile broth media; n = 12), positive control (Brachyspira hampsonii genomovar 2 strain 30446; n = 18), and 3603-F2 (n = 12) or G79 (n = 12). Fecal scoring and rectal swabbing for culture were performed daily. Animals were euthanized following onset of mucohemorrhagic diarrhea or between 21 and 28 days post inoculation (dpi). Gross and microscopic pathology were assessed. Terminal colon samples were used to characterize post-infection mucosal ion secretion. Results: Both strains were moderately hemolytic. Whole genome and nox sequencing identified 3603-F2 as Brachyspira murdochii and G79 as a novel strain. Both challenge trials revealed intestinal colonization, but no mucohemorrhagic diarrhea. Sporadic watery diarrhea was induced by 3603-F2 associated with a pattern of microscopic lesions similar to pigs with swine dysentery (positive controls). No diarrhea was observed in G79 inoculated pigs, but microscopic lesions were more severe than in controls. Both strains induced greater colonic anion secretory potential than negative controls 21 dpi. Implications: Allegedly avirulent Brachyspira species most closely related to B murdochii can be associated with subclinical colitis and may be a concern for grow-finish pigs.
Impact assessment of new US Food and Drug Administration regulations on antibiotic use: A post-enactment survey of swine practitioners
Authors: Rademacher Christopher , Pudenz Christopher , Schulz Lee
Published: August 2023

Following a 2016 pre-enactment survey, 42 swine veterinary practitioners were surveyed in 2017 to assess post-enactment impacts of the revised Veterinary Feed Directive (VFD). The survey evaluated veterinarian-client-patient relationships, client recruitment, VFD fees and creation, record keeping, education and training, business costs, and changes in antibiotic usage and on-farm management.
Development of a herd-specific lung homogenate for exposure to Mycoplasma hyopneumoniae under field conditions
Authors: Robbins Rebecca , Betlach Alyssa , Mondragon-Evans Maria , Pieters Maria
Published: August 2023

The swine industry is known for holding high standards of disease control and elimination. However, partial disease control for Mycoplasma hyopneumoniae at the farm level has been evident and has driven initiatives for unconventional health management strategies. Several approaches focused on gilt exposure for M hyopneumoniae using a herd-specific lung homogenate have been performed in the field. Nevertheless, variations in efficacy are apparent and a publicly available protocol for producing M hyopneumoniae lung homogenate under field conditions is not available. In this practice tip, a protocol is described for developing a herd-specific lung homogenate for M hyopneumoniae exposure intended for use in veterinary-supervised elimination or control programs. A herd-specific lung homogenate inoculum, free of secondary respiratory pathogens for the herd of intended use and with an adequate M hyopneumoniae concentration, was obtained through extensive diagnostic testing and evaluation of M hyopneumoniae localization within the lung. Molecular methods were applied to characterize the M hyopneumoniae present in the lung and to evaluate the genomic stability of the bacterium during the exposure process. In doing so, a herd-specific M hyopneumoniae lung homogenate for gilt acclimation was obtained under field conditions.
Evidence of improved reporting of swine vaccination trials in the post-REFLECT statement publication period
Authors: Moura Cesar , Totton Sarah , Sargeant Jan , O'Sullivan Terri , Linhares Daniel , O'Connor Annette
Published: August 2023

Objectives: Describe and compare the proportion of studies reporting the method used to assign study units to treatment groups, reporting a random allocation approach, reporting 18 REFLECT items, and the proportion of studies having a low risk-of-bias assessment in swine vaccination trial studies published after the REFLECT statement, compared to studies published before. Materials and Methods: The study population was 61 studies that evaluated vaccines targeted at pathogens affecting swine health or pork safety. Two reviewers assessed the reporting of 18 of 22 REFLECT items and 5 risk-of-bias domains. Results: Authors reported the method used to allocate experimental units in 33 of 42 (79%) and 14 of 19 (74%) studies published prior to and following REFLECT, respectively. There has been a substantial shift in the reporting of allocation approaches. Before 2011, only 2 of 25 (8%) studies that reported using random allocation provided supporting evidence. This increased in studies published between 2011-2017 (4 of 6; 66%). Before 2011, 8 of 33 (24%) studies reported using systematic allocation, which increased to 43% (6 of 14 studies) between 2011-2017. There has also been an increase in the prevalence of reporting for 14 of the 18 REFLECT items. There was an increase in the number of studies reporting evidence to support true randomization to group and data that suggests few baseline imbalances. Implications: Data from this study suggests swine vaccination trial reporting improved, which may be due to researchers having more access to better quality information.
Dexmedetomidine mediates the mechanism of action of ferroptosis in mice with Alzheimer’s disease by regulating the mTOR-TFR1 pathway
Authors: Qiao Li , Li Gang , Yuan Hong-Xun
Published: August 2023

Rapid-cycling bipolar disorder (RCBD) is a phase of bipolar disorder defined by the presence of ≥ 4 mood episodes in a year. It is a common phenomenon characterized by greater severity, a predominance of depression, higher levels of disability, and poorer overall outcomes. It is resistant to treatment by conventional pharmacotherapy. The existing literature underlines the scarcity of evidence and the gaps in knowledge about the optimal treatment strategies for RCBD. However, most reviews have considered only pharmacological treatment options for RCBD. Given the treatment-refractory nature of RCBD, nonpharmacological interventions could augment medications but have not been adequately examined. This review carried out an updated and comprehensive search for evidence regarding the role of nonpharmacological therapies as adjuncts to medications in RCBD. We identified 83 reviews and meta-analyses concerning the treatment of RCBD. Additionally, we found 42 reports on adjunctive nonpharmacological treatments in RCBD. Most of the evidence favoured concomitant electroconvulsive therapy as an acute and maintenance treatment. There was preliminary evidence to suggest that chronotherapeutic treatments can provide better outcomes when combined with medications. The research on adjunctive psychotherapy was particularly scarce but suggested that psychoeducation, cognitive behavioural therapy, family interventions, and supportive psychotherapy may be helpful. The overall quality of evidence was poor and suffered from several methodological shortcomings. There is a need for more methodologically sound research in this area, although clinicians can use the existing evidence to select and individualize nonpharmacological treatment options for better management of RCBD. Patient summaries are included to highlight some of the issues concerning the implementation of adjunctive nonpharmacological treatments.
Effect of cognitive behavioral group therapy on rehabilitation of community patients with schizophrenia: A short-term randomized control trial
Authors: Chen Xue-Lian , Deng Xiao-Ting , Sun Fu-Gang , Huang Qing-Jun
Published: August 2023

Rapid-cycling bipolar disorder (RCBD) is a phase of bipolar disorder defined by the presence of ≥ 4 mood episodes in a year. It is a common phenomenon characterized by greater severity, a predominance of depression, higher levels of disability, and poorer overall outcomes. It is resistant to treatment by conventional pharmacotherapy. The existing literature underlines the scarcity of evidence and the gaps in knowledge about the optimal treatment strategies for RCBD. However, most reviews have considered only pharmacological treatment options for RCBD. Given the treatment-refractory nature of RCBD, nonpharmacological interventions could augment medications but have not been adequately examined. This review carried out an updated and comprehensive search for evidence regarding the role of nonpharmacological therapies as adjuncts to medications in RCBD. We identified 83 reviews and meta-analyses concerning the treatment of RCBD. Additionally, we found 42 reports on adjunctive nonpharmacological treatments in RCBD. Most of the evidence favoured concomitant electroconvulsive therapy as an acute and maintenance treatment. There was preliminary evidence to suggest that chronotherapeutic treatments can provide better outcomes when combined with medications. The research on adjunctive psychotherapy was particularly scarce but suggested that psychoeducation, cognitive behavioural therapy, family interventions, and supportive psychotherapy may be helpful. The overall quality of evidence was poor and suffered from several methodological shortcomings. There is a need for more methodologically sound research in this area, although clinicians can use the existing evidence to select and individualize nonpharmacological treatment options for better management of RCBD. Patient summaries are included to highlight some of the issues concerning the implementation of adjunctive nonpharmacological treatments.
Global research trends and mapping knowledge structure of depression in dialysis patients
Authors: Al-Jabi Samah W
Published: August 2023

Rapid-cycling bipolar disorder (RCBD) is a phase of bipolar disorder defined by the presence of ≥ 4 mood episodes in a year. It is a common phenomenon characterized by greater severity, a predominance of depression, higher levels of disability, and poorer overall outcomes. It is resistant to treatment by conventional pharmacotherapy. The existing literature underlines the scarcity of evidence and the gaps in knowledge about the optimal treatment strategies for RCBD. However, most reviews have considered only pharmacological treatment options for RCBD. Given the treatment-refractory nature of RCBD, nonpharmacological interventions could augment medications but have not been adequately examined. This review carried out an updated and comprehensive search for evidence regarding the role of nonpharmacological therapies as adjuncts to medications in RCBD. We identified 83 reviews and meta-analyses concerning the treatment of RCBD. Additionally, we found 42 reports on adjunctive nonpharmacological treatments in RCBD. Most of the evidence favoured concomitant electroconvulsive therapy as an acute and maintenance treatment. There was preliminary evidence to suggest that chronotherapeutic treatments can provide better outcomes when combined with medications. The research on adjunctive psychotherapy was particularly scarce but suggested that psychoeducation, cognitive behavioural therapy, family interventions, and supportive psychotherapy may be helpful. The overall quality of evidence was poor and suffered from several methodological shortcomings. There is a need for more methodologically sound research in this area, although clinicians can use the existing evidence to select and individualize nonpharmacological treatment options for better management of RCBD. Patient summaries are included to highlight some of the issues concerning the implementation of adjunctive nonpharmacological treatments.
PEMBELAJARAN MATEMATIKA TENTANG PENGUKURAN WAKTU, PANJANG DAN BERAT DI SEKOLAH DASAR
Authors: Unaenah Een , Rafidah Aura Rahmatun , Tsabitah Jihan Fitri , Septia Nirmala
Published: August 2023

The purpose of this research is to describe how well the students at SDN Cipondoh 02 which is located on Jl. KH Hasyim Ashari, RT.002/RW.01, Nerogtog, Kec. Pinang, Kota Tangerang, Banten 15148, understands the material for measuring time, length and weight. This study looked at how well students understood the material for measuring length, time, and weight. This survey was conducted on 25 students, which was also conducted through interviews with the homeroom teacher of class IV students at SDN Cipondoh 02. Many students already understand measurement, but there are students who still don't understand it, according to the results of interviews and studies that have been conducted. The methods used to obtain this information are interviews, observation, and asking questions (tests). After getting the results, the data is then examined using qualitative data analysis techniques. Based on interviews, observations, and asking questions (tests), 75% of students already know the content of the measurement, and 25% of students still have difficulty understanding it. This is caused by various circumstances that affect students.
Introduction to doors Workshops on Edge Computing (2021-2023)
Authors: Vakaliuk Tetiana A. , Semerikov Serhiy O.
Published: August 2023

The Edge Computing Workshop, known as "doors", has evolved as a prominent international forum for researchers, practitioners, and industry experts to converge and discuss the latest advancements and applications in the field of edge computing. This paper provides an overview of the doors workshops held from 2021 to 2023, highlighting their objectives, topics of interest, committees, and the significant contributions made by researchers during these years. The workshops have played a pivotal role in fostering collaboration, sharing insights, and exploring emerging trends in edge computing, addressing challenges related to infrastructure, systems, security, applications, and more. This paper underscores the importance of these workshops in advancing the field and promoting innovation in the era of digital transformation.
Đánh giá công tác lập và thực hiện quy hoạch, kế hoạch sử dụng đất cấp huyện: trường hợp nghiên cứu tại huyện Thọ Xuân, tỉnh Thanh Hóa
Authors: Tám Đỗ Thị , Hiệu Đỗ Đình , Linh Trương Đỗ Thùy , Hạnh Nguyễn Thị Hồng
Published: August 2023

Nghiên cứu nhằm đánh giá thực trạng và đề xuất giải pháp nâng cao hiệu quả lập và thực hiện quy hoạch, kế hoạch sử dụng đất (QH, KHSDĐ) giai đoạn 2011-2020 và KHSDĐ năm 2021 huyện Thọ Xuân, tỉnh Thanh Hóa. Các phương pháp nghiên cứu sử dụng là: điều tra thứ cấp, điều tra sơ cấp, đánh giá theo thang đo 5 cấp của Likert, T-test và đánh giá theo độ lệch giữa kế hoạch và thực hiện. Kết quả cho thấy về thời gian QH, KHSDĐ được duyệt rất chậm so với kế hoạch đề ra. Tên gọi các chỉ tiêu sử dụng đất (SDĐ) trong các phương án QH, KHSDĐ giữa các thời kỳ có sự khác biệt rất nhiều. Về tỉ lệ diện tích thực hiện, trong tổng số 74 chỉ tiêu sử dụng đất có 42 chỉ tiêu (chiếm 56,76%) đạt mức thực hiện rất tốt (13 chỉ tiêu đất nông nghiệp, 28 chỉ tiêu đất phi nông nghiệp). Có tới 17 chỉ tiêu SDĐ (chiếm 37,04%) thực hiện ở mức rất kém (100% là đất phi nông nghiệp). Kết quả điều tra 100 cán bộ cho thấy trong 14 tiêu chí có 3 tiêu chí được đánh giá ở mức rất tốt; 5 tiêu chí ở mức tốt, 3 tiêu chí ở mức trung bình; 3 tiêu chí ở mức độ kém. Từ đó đề xuất giải pháp để nâng cao hiệu quả công tác lập và thực hiện QH, KHSDĐ.
L52328 Composite Repair of Mechanically-Damaged Pipes
Authors: Alexander  , Bedoya
Published: August 2023

Composite materials continue to gain wider acceptance in the pipeline industry for repairing a range of pipeline anomalies. This success is due in large part to two factors. The first contributor is the execution of comprehensive research programs such as the first PRCI MATR-3-3, State of the Art Assessment of Composite Repair Systems and this second program contained herein focused on evaluating composite materials to repair damaged pipelines. The second factor associated with the widespread use of composite materials is the successful two-decade history that composite materials have had in repairing pipelines. While there have been a few unfortunate incidents in the field (primarily related to poor installation), composite materials have proven themselves to be well suited for repairing high pressure gas and liquid pipelines. The need existed for a set of integrity assessment procedures and guidelines to ensure proper use and application of composite repair materials for mechanically-damaged pipes.

The results of this program indicate that when properly designed and installed, composite repair systems are able to restore integrity to mechanically-damaged pipes to a state that makes them fit for continued use at their normal design conditions. When composite materials are used for repairs, whether the repair involves corrosion, dents, or other anomalies, an integrity assessment should be completed. The integrity assessment procedures and guidelines presented in this report include an estimate of the future operating conditions to ensure that the design is adequate for the intended service.
L30050 Feasibility of Basing Natural Gas Pipeline Operating Pressure on Hydrostatic Test Pressure
Authors: Duffy
Published: August 2023

This report presents the results of a study to determine whether natural gas pipeline operating pressure could be based on some percent of hydrostatic test pressure versus the currently used percent of specified minimum yield strength. The study included the following:

- A study of hydrostatic testing techniques;

- Analysis of hydrostatic test data of many thousands of miles of pipe tested to actual yield in the field and analysis of the operating experience of these lines;

- Results of full-scale experiments to study the relation between flow size and failure pressure;

- Results of investigation of the behavior of defects in a yield environment; and

- Compilation and appraisal of important factors necessary for evaluating the feasibility of basing operating pressure on the hydrostatic test pressure.

Analysis includes an assessment as to if it is both technically feasible and desirable to set the allowable operating pressure as a percentage of the hydrostatic test pressure level.
PR-276-094509-R01 Develop Fracture Initiation Criteria for High-Strength Steel Line Pipe Phase II
Authors: Shim D. J. , Wilkowski Gery , Uddin Mohammed , Kalyanam Sureshkumar , Mincer P.
Published: August 2023

This report summarizes the major findings from a PRCI Project on developing fracture initiation criteria for axial flaws (both through-wall and surface flaws) in high-strength line-pipe materials. This work was originally done on the basis to see if improvements were needed for higher-grade steels, but interestingly there were several outcomes that affect predictions for all piping steels. One of the outcomes of this work is a new correlation between Charpy USE and J-R curve for high-strength materials. Although it is based on limited data, it was demonstrated that there is significant difference compared to the existing correlation. Another interesting finding is the effect of the internal patch on burst pressure of axial through-wall-cracked pipe test. Careful experimental and detailed finite element analyses showed patching affects burst pressure by at least 10-percent which affects the leak-rupture boundary. For axial surface-cracked pipes, the effect of crack shape on the crack-driving force was investigated. Finally, it was demonstrated that the actual axial surface-cracked pipe bulging factor is considerably lower than bulging factor empirically derived at Battelle in the 1970s. If past bulging factor is used for subcritical crack growth (e.g., for SCC or fatigue analyses), the crack growth and start of ductile tearing can be significantly overpredicted. Overall, J-T analysis provided the most accurate results when proper crack-driving forces and J-R curves were used (both for axial through-wall-cracked pipe and axial surface-cracked pipe). This report also includes recommendations for future work.
L51436 Brittle Fracture Arrest in Gas Pipelines
Authors: Maxey  , Kiefner  , Eiber
Published: August 2023

The phenomenon of brittle fracture arrest has been studied by Battelle Columbus Laboratories for the Pipeline Research Council International, Inc. and for the British Gas Corporation (BGC). Pertinent studies have been made independently by BGC for both steel and plastic (PVC) pipes. These studies have revealed that it is possible to obtain arrest of brittle or cleavage fractures propagating in natural gas pipelines under certain conditions..

The specific purpose of this report is to combine the previous work on brittle fracture initiation, propagation, and arrest into a consistent hypothesis, to show how this hypothesis can be used in design, and to show how current API specifications can be used to accomplish these designs or, alternatively, what additional supplementary requirements need to be added to API specifications. Current API 5LX Line Pipe Specifications have Supplementary Requirements SR5 and SR6, which relate to Charpy V-notch (CVN) Impact Testing and Drop Weight Tear Testing (DWTT), respectively, for 20-inch-diameter or larger pipe. Most of the experimental work, also, has been on pipes in this size category. Consequently, the analysis here will be pertinent mainly to the larger pipe sizes. This report describes the conditions that are necessary for control of propagating brittle fractures and also suggests other considerations with regard to fracture initiation.