bluuebunny/crossref_metadata_2025 huggingface dataset:
Ekstrak Daun Meniran (Phyllanthus niruri L.) : Bagaimana Pengaruhnya Terhadap Jumlah Trombosit di Dalam Darah?
Authors: Sumiati Risma Laila , Baehaki Farhan , Nurdin Nurdin , Pakpahan Suyarta Efrida
Published: June 2024

Thrombocytopenia is a condition in which the platelet count is below normal (<150,000-450,000 cells/mm3). Until now, the treatment of thrombocytopenia has not yet found a specific drug and there are side effects from chemical treatment, so alternative solutions are needed, one of which is the use of meniran leaves (Phyllanthus niruri L.). The meniran plant is a wild plant that is often found in the wild, on the streets, as well as vacant land so that people can easily get these plants. The aim of this research was to determine the effect of meniran leaf extract (Phyllanthus niruri L.) on the number of platelets in mice induced by sodium phenytoin. The method used in this research was True Experimental with Pretest and Posttest with Control Group Design consisting of 5 groups which aimed to determine the effect of meniran leaf extract on platelet counts. The data collection technique used in this study used primary data, which was obtained from the results of examining platelet counts on day 0, day 3 after induction and day 7 after treatment with meniran leaf extract (Phyllanthus niruri L.). Then the data obtained was tested using SPSS with the non-parametric Kruskal-Wallis and Mann-Whitney tests. From 25 experimental animals, the results showed that there was a relatively significant increase in the number of platelets after being given therapy with meniran leaf extract (Phyllanthus niruri L.) but there was no difference between each dose. Based on the research results, it can be concluded that meniran leaf extract (Phyllanthus niruri L.) has an effect on increasing the number of platelets.
Ionic Conductivity Test of Chitosan Solid Electrolyte Polymer Membrane with the Addition of Ionic Liquid
Authors: Multazam Multazam , Ridwan Mohammad Ibnu , Ndruru Sun Theo C.L.
Published: June 2024

Lithium ion batteries are an alternative choice for fulfillment as an energy source. Beside that, lithium ion batteries are also use as energy storage. However, lithium ion batteries still use a liquid electrolyte which has the advantages of being toxic, explosive, and corrosive. So we need an alternative to replace liquid electrolyte, namely solid electrolyte membranes. The aim of this research is to determine the effect of adding ionic liquid [EMIm]Ac to chitosan polymer as a solid electrolyte polymer (SEP) membranes. Based on the resulta obtained, chitosan has been successfully isolated from chitin. Chitin isolated from shrimp shells. Based on the ionic conductivity value, the SEP membrane with the addition of 15% [EMIm]Ac ionic liquid has the highest ionic conductivity value, namely 5.02 x 10-5 S cm-1.
Analysis Of Caffeine In Packaged Drinks Using Thin Layer Chromatography (TLC) and Spectrophotometry Method
Authors: Munir Muhammad Abdurrahman , Emelda Emelda , Fatmawati Annisa , Nurhidayanti Nurhidayanti
Published: June 2024

Caffeine is a natural alkaloid compound found in plants in the leaves, seeds and fruit. The decision of the Food and Drug Supervisory Agency regarding provisions for supervision of supplements in Chapter VIII Article 18 paragraph two states that caffeine levels must not exceed 150 mg/day. The aim of this research was to find out caffeine level in energy beverages. This research method applied the UV-Vis spectrophotometry method and the TLC method. The maximum wavelength obtained in this study was 272.55 nm and the linear results and correlation coefficient obtained were obtained. The linearity value obtained at y= 0.0381x + 0.3285 with the correlation equation R2= 0.9389. Caffeine levels obtained from “brand A” energy drink powder samples for first replicate at 49.59 mg/g, second replicate was 48.78 mg/g, third replicate was 47.15 mg/g, and “brand B” sample for first replicate was 31.5625 mg/g, second replicate at 32.375 mg/g. The caffeine levels obtained in the “brand C” sample from first replicate at 59.43 mg/g, second replicate was 60.28 mg/g, and third replicate was 60.09 mg/g. The results of the standard Rf value for caffeine standard were 0.7, the “brand A” energy drink powder sample was 0.75, the “brand B” sample was 0.75 and the “brand C” was 0.75. The conclusion from this research was that the maximum wavelength was 272.55 nm, which was slightly different from the theoretical maximum wavelength of pure caffeine, namely 273 nm. The caffeine levels obtained for samples of energy drink powder from brands A and B met the requirements because it was <50 mg/package and brand C did not meet the requirements because it was >50mg/package. The Rf value results are satisfactory because they were at range 0.2-0.8.
Transforming Halal Training Through Gamification and Immersive Technology to Empower Talents
Authors: Masood Adlin , Mohd Anim Nur Aqilah Hazirah , Ismail Anita
Published: June 2024

With a 4-year Compound Annual Growth Rate (CAGR) of 7.5%, the Halal economy is estimated to reach US$2.8 trillion by 2025. To obtain and retain Halal certification, businesses must guarantee that their workers are knowledgeable and skilled. Implementing Halal-toyyiban in businesses can be complex, especially when the manufacturing entities are owned and managed by non-Muslims. Therefore, developing a Halal training programme is crucial. The main challenge is ensuring that trainees can retain and recall what they have learned, ultimately changing their work culture and mindset. To address this challenge, corporate Halal training programmes must include built-in learning retention elements, such as gamification through games. Gamification can enhance employee engagement and safety awareness, reduce training costs, and lower learning curves. Moreover, recent technological advancements in Augmented Reality (AR), Mixed Reality (MR), and gamification enhance user experience and performance in various domains. AR and MR are viable options as they can include aspects of the current environment in real-time and present a combination of the virtual world and reality. This study explores the viability of AR and MR gamified Halal training to empower Halal workers for businesses’ sustainability and expansion. The study reviews and analyses published literature from bibliographic and other acknowledged sources. Consequently, the authors discovered that while AR and gamification have been used extensively, combining both to enhance experiential learning and immersive experience is in its infancy. The findings suggest that leveraging these options can lead to future-oriented Halal training that improves experiential and immersive learning and is accessible anytime and anywhere.
Defining Inheritance Risk Management as A New Concept Towards Sustainability of Family Businesses
Authors: Abdulbasit Lutfy A. Al Obaidy  , Teoh Ai Ping  , Ganesan Yuvaraj , Alzaqeba Murad Ali Ahmad
Published: June 2024

This study investigates the relationship between success, Inheritance Risk Management (IRM), and sustainability in family businesses. This paper is based on a quantitative approach. The population includes family-owned businesses located in Abu Dhabi that have been in operation for at least two generations. The study sample consisted of family-owned business members. However, this paper focuses only on measuring variables and testing hypotheses for the proposed measurement. Due to the complexity of the model, Smart PLS-4 was used. Through an analysis of empirical data and theoretical frameworks, the research explores the direct and mediated relationships between these key variables. The findings underscore the critical role of success in driving effective risk management practices within family enterprises. Furthermore, the study highlights the significance of IRM in promoting the sustainability and resilience of family businesses over time. The results reveal a direct positive correlation between success and sustainability, emphasizing the importance of achieving and maintaining success for long-term viability. Additionally, the mediating role of IRM underscores its crucial contribution to the overall sustainability of family businesses. The study identifies various challenges in managing inheritance risks and ensuring the continuity of family enterprises, including maintaining family control, balancing family and operational responsibilities, succession planning, grooming successors, and respecting family elders. By addressing these challenges and leveraging IRM strategies, family businesses can navigate uncertainties and capitalize on opportunities, ensuring continued success across generations. These findings provide valuable insights for strategic decision-making and resource allocation in family enterprises, guiding efforts to enhance governance structures, succession planning, and risk mitigation practices. In addition, this research contributes to advancing our understanding of the complexities surrounding family businesses and underscores the importance of proactive risk management and strategic planning for long-term sustainability.
Peripheral muscular strength and functionality as predictors of extubation success after myocardial revascularization
Authors: Cordeiro André Luiz Lisboa , Mascarenhas Hayssa de Cássia , Soares Lucas Oliveira , Pimentel Vitória de Oliveira , Souza e Souza Layla , Marchesini Arthur , Ferreira Gabriel Velloso Dantas Batista Andrade , Guimarães André Raimundo
Published: June 2024

Introduction: Maximum inspiratory pressure (MIP) and the rapid and shallow breathing index are predictors for successful extubation. Peripheral muscle strength and functionality appear as possible predictors of success for extubation in other patient profiles, however, there is little evidence in patients undergoing to Coronary Artery Bypass Grafting (CABG). Objective: To assess peripheral muscle strength and functionality as predictors of success for extubation in patients undergoing to CABG. Methods: Prospective cohort study. At the time of hospital admission, patients were assessed for MIP, maximum expiratory pressure (MEP), Medical Research Council (MRC), peak of expiratory flow (PEF) and Functional Independence Measure (FIM). Patients were divided into two groups: Success Group (SG), which remained on spontaneous ventilation for more than 48 hours, and failure group (FG) that required invasive support in less than 48 hours. We compared the influence of muscle strength, cough and functionality variables between these groups. Results: 74 patients, Success Group (n = 59) and Failure Group (n = 15), were evaluated. The CI 95% was -1 (-5.33 to 3.33) in MIP, 4 (2.14 to 5.86) in MEP, 13 (-35.31 to 61.31) in PEF, 7 (6.27 to 7.73) in the MRC and 9 (8.08 to 9.92) in the FIM. Conclusion: Peripheral, expiratory muscle strength and functionality demonstrated a statistically significant influence on the success of extubation in patients after CABG.
Correlação entre a frequência de treinamento e o estado humor de corredores de rua: estudo transversal
Authors: Moraes Bárbara Celina , Santos Ana Lívia dos , Simola Rauno Álvaro de Paula , Santos Andrêza Soares dos , Salgado José Vítor Vieira
Published: June 2024

Introdução: Este estudo investiga a correlação entre frequência de treinamento e o estado de humor em praticantes de corrida de rua. Destaca-se a crescente popularidade da corrida de rua e seus benefícios para a saúde física e mental. Métodos: Foi realizado um estudo de natureza transversal, empregando questionário online para coletar dados sociodemográficos, informações sobre a prática esportiva e avaliação do estado de humor por meio da Escala de Humor de Brunel (BRUMS). A análise estatística, conduzida no SPSS 25, tendo os dados descritos como média ± desvio padrão. Resultados: Os resultados da pesquisa apontam que a frequência de treinamento não demonstrou correlação significativa com a melhoria no estado de humor. Conclusão: Destaca-se a importância do cuidado com a saúde mental para otimizar o desempenho esportivo e sugere-se a necessidade de estudos adicionais para uma compreensão mais abrangente dessas dinâmicas.
Efeitos do jejum intermitente em variáveis fisiológicas e psicobiológicas no Taekwondo durante período pré-competitivo
Authors: Magalhães Júlia Pessoa , Araujo Igor Natan Rodrigues , Silva Ronaldo Ângelo Dias da , Drummond Marcos Daniel Motta
Published: June 2024

Objetivo: Investigar os efeitos do jejum intermitente de 12 horas, realizado ao longo de quatro semanas, no período pré-competitivo de treinamento do Taekwondo, em variáveis fisiológicas e psicobiológicas. Métodos: A amostra foi composta por 9 atletas de Taekwondo (idade 18,4 ± 3,3 anos; peso 63,58 ± 6,57 kg; altura 1,72 ± 0,05 metros; experiência na modalidade de 9,2 ± 3,4 anos), de ambos os sexos. Como critério de inclusão, os atletas deveriam ser eutróficos e objetivar redução da massa corporal. A duração total do estudo foi de 6 semanas, sendo as 2 primeiras destinadas a familiarização e confiabilidade, enquanto nas 4 semanas seguintes foi realizado o treinamento, com jejum intermitente de 12 horas, em um período pré-competitivo. Foram avaliadas as seguintes variáveis, antes, durante e após o período de 4 semanas de treinamento: escala de recuperação percebida, variabilidade da frequência cardíaca, percepção subjetiva do esforço da sessão. A avaliação da qualidade de sono foi realizada antes e após o período deste treinamento. Resultados: Não foram encontradas diferenças significativas na escala de recuperação percebida, assim como na variabilidade da frequência cardíaca. Na avaliação da qualidade de sono também não foram encontradas diferenças significativas na “hora de acordar”, na “duração do sono” e no “score global”. A percepção subjetiva do esforço sessão também não apresentou diferenças significativas ao longo do estudo. Conclusão: O jejum intermitente de 12 horas, realizado ao longo de 4 semanas, durante o período pré-competitivo de treinamento de Taekwondo, não influencia negativamente em variáveis fisiológicas e psicobiológicas.
Chimeric antigen receptor T-cell therapy in childhood acute myeloid leukemia: how far are we from a clinical application?
Authors: Naik Swati , Velasquez M. Paulina , Gottschalk Stephen
Published: June 2024

Recurrent and/or refractory (R/R) pediatric acute myeloid leukemia (AML) remains a recalcitrant disease with poor outcomes. Cell therapy with genetically modified immune effector cells holds the promise to improve outcomes for R/R AML since it relies on cytotoxic mechanisms that are distinct from chemotherapeutic agents. While T cells expressing chimeric antigen receptors (CAR T cells) showed significant anti-AML activity in preclinical models, early phase clinical studies have demonstrated limited activity, irrespective of the targeted AML antigen. Lack of efficacy is most likely multifactorial, including: (i) a limited array of AML-specific targets and target antigen heterogeneity; (ii) the aggressive nature of R/R AML and heavy pretreatment of patients; (iii) T-cell product manufacturing, and (iv) limited expansion and persistence of the CAR T cells, which is in part driven by the immunosuppressive AML microenvironment. Here we review the results of early phase clinical studies with AML-specific CAR T cells, and avenues investigators are exploring to improve their effector function.
Allogeneic chimeric antigen receptor T cells for children with relapsed/refractory B-cell precursor acute lymphoblastic leukemia
Authors: Locatelli Franco , Del Bufalo Francesca , Quintarelli Concetta
Published: June 2024

Chimeric antigen receptor (CAR) T-cell therapy has emerged as a breakthrough cancer therapy over the past decade. Remarkable outcomes in B-cell lymphoproliferative disorders and multiple myeloma have been reported in both pivotal trials and real-word studies. Traditionally, the use of a patient’s own (autologous) T cells to manufacture CAR products has been the standard practice. Nevertheless, this approach has some drawbacks, including manufacturing delays, dependence on the functional fitness of the patient’s T cells, which can be compromised by both the disease and prior therapies, and contamination of the product with blasts. A promising alternative is offered by the development of allogeneic CAR-cell products. This approach has the potential to yield more efficient drug products and enables the use of effector cells with negligible alloreactive potential and a significant CAR-independent antitumor activity through their innate receptors (i.e., natural killer cells, γδ T cells and cytokine induced killer cells). In addition, recent advances in genome editing tools offer the potential to overcome the primary challenges associated with allogeneic CAR T-cell products, namely graft-versus-host disease and host allo-rejection, generating universal, off-the-shelf products. In this review, we summarize the current pre-clinical and clinical approaches based on allogeneic CAR T cells, as well as on alternative effector cells, which represent exciting opportunities for multivalent approaches and optimized antitumor activity.
Розвиток дослідницької компетентності майбутніх менеджерів освіти засобами цифрових технологій в умовах магістратури
Authors: Махиня Тетяна
Published: June 2024

Стаття носить прикладний характер та ґрунтується на результатах анонімного онлайн опитування здобувачів другого (магістерського) рівня вищої освіти освітньо-професійної програми «Управління навчальним закладом» щодо готовності до використання цифрових технологій у процесі розвитку їх дослідницької компетентності в умовах магістратури.
Дослідженням було охоплено 72 здобувачів першого та другого року навчання із числа педагогічних працівників закладів освіти різних типів та форм власності усіх регіонів України. Опитування проводилося у 2023/24 навчальному році на кафедрі педагогіки, адміністрування і спеціальної освіти ДЗВО «Університет менеджменту освіти».
Результати опитування дозволили констатувати, що майбутні менеджери в цілому розуміють сутність поняття «дослідницька компетентність» та визначають його провідну роль у власному професійному становленні. На основі самоаналізу готовності майбутніх менеджерів освіти до використання цифрових технологій на різних етапах наукових досліджень встановлено, що більше 58 % опитаних вважають, що їм притаманний достатній рівень та зацікавлені у його підвищенні в умовах магістратури.
На основі виокремлення проблемних моментів у формування дослідницької компетентності майбутніх менеджерів освіти в умовах магістратури визначено шляхи удосконалення змісту освітньо-професійної програми «Управління навчальним закладом» у ДЗВО «Університет менеджменту освіти». Результати опитування дозволили переглянути структуру індивідуальних науково-дослідних завдань з дисципліни «Методологія наукових досліджень» та осучаснити зміст завдань відповідно до сучасного стану розвитку цифрових технологій збору, аналізу та представлення даних, а також для співпраці та спільної роботи з колегами та іншими дослідниками.
Reducción del Impacto Ambiental con Desechos Industriales en Pavimentos por Análisis del California Bearing Ratio
Authors: Torres-Hoyer Roberto , Peña Jackeline , Millalén Fernanda , Picón Ricardo , Barreto Wilmer , Peña Oswaldo , Torres-Hoyer Jesús
Published: June 2024

La sub-base del pavimento requiere materiales adecuados para el soporte necesario. Tradicionalmente, se ha utilizado material de préstamo, lo que genera un impacto ambiental. Este estudio analizó el potencial de reutilizar cenizas de desecho industrial depositadas en vertederos. Se realizaron ensayos de laboratorio mezclando el suelo con diferentes proporciones de cenizas. Se determinó la relación entre humedad y peso seco del suelo, se realizó el ensayo C.B.R. (California Bearing Ratio) y se calculó el espesor de pavimentos, con un mismo espesor de sub-base. A medida que aumenta el porcentaje de cenizas, la calidad del suelo disminuye, pero sigue cumpliendo los requisitos para ser utilizado como sub-base. Se recomienda considerar las cenizas de desecho industrial como un material de reciclaje viable en la construcción de pavimentos, lo que reduciría el impacto ambiental asociado a su disposición en vertederos.
La Evaluación Fisicomecánica del Concreto al Adicionar Cenizas del Tallo de Algarrobo para Pavimentos Rígidos - Ayacucho, Perú
Authors: Alex Farfan , Quispe Yuan , Vildoso Alejandro
Published: June 2024

Los pavimentos rígidos están sujetos a transmisiones de cargas vehiculares que producen fisuras y grietas, debido a un mal diseño. Esto afecta al tránsito vehicular y al medio ambiente. El objetivo del estudio es conocer la influencia de la ceniza del tallo de algarrobo (CTA) para el concreto de diseño f’c 210 Kg/cm2. En el cual, se incorporó una serie de dosificaciones del 0 % (concreto patrón), 5 %, 8 % y 12 % de CTA. El estudio presenta una técnica cuantitativa y diseño cuasiexperimental. Se realizó un total de 60 muestras de concreto: divididas en 36 probetas cilíndricas de 15 x 30 cm para compresión, 12 viguetas de 15 x 15 x 50 cm para flexión y 12 discos de concreto de 5 x 10 cm para abrasión. Los resultados, a los 28 días, fueron los siguientes: al (0 %) de 243 Kg/cm2, 5 % de 247 Kg/cm2, 8 % de 224 Kg/cm2 y 12 % de 216 Kg/cm2; para las resistencias a compresión. Concreto patrón (0 %) de 26 Kg/cm2, 5 % de 29 Kg/cm2, 8 % de 30 Kg/cm2 y 12 % de 31 Kg/cm2 para las resistencias a flexión. Concreto patrón (0 %) con un desgaste de 0.63 %, 5 % con un desgaste de 0.66 %, 8 % con un desgaste de 0.74 % y 12 % con un desgaste de 0.77 % para las resistencias a abrasión. Se concluye que el porcentaje óptimo e ideal es la adición parcial de CTA al 5 %; donde mejoran las características mecánicas del concreto en el diseño de pavimento rígido.
Metodologia de pesquisa em Educação Matemática: complementaridade otteana baseada na semiótica
Authors: De Assis Clímaco Humberto , Borges de Paula Jacqueline , Figueiredo da Silva Santana Geslane
Published: June 2024

Neste artigo, a "Complementaridade otteana fundamentada na Semiótica" é apresentada como uma metodologia de pesquisa em Educação Matemática. Os fundamentos filosóficos e epistemológicos que embasam essa metodologia são explorados, destacando-se seu papel na investigação educacional. São demonstradas diferentes abordagens práticas da mencionada Complementaridade, por meio de alguns exemplos de pesquisas que a utilizaram como base. Encerra-se o relato deste estudo, expondo as principais conclusões: a importância de abordar o caráter social e histórico da Matemática para compreender a própria natureza da disciplina Matemática, a compreensão de que a interdisciplinaridade é um fator central para a fundamentação da Educação Matemática e o entendimento de que adotar uma abordagem metodológica de pesquisa, sustentada na abordagem da Complementaridade otteana, exige que o pesquisador em Educação Matemática assuma o propósito de construção e constituição de uma “sempre renovada” postura investigativa, a cada problema e objeto que se pretende investigar.
Percepções docentes sobre as práticas pedagógicas da educação infantil utilizadas na vigência da pedagogia histórico-crítica em um município da região norte paranaense
Authors: Abreu Bueno Lucineide , Lema Mazzafera Bernadete
Published: June 2024

Objetivou-se compreender as percepções dos professores em relação às práticas pedagógicas, a partir da Pedagogia Histórico-Crítica, a fim de identificar suas aplicações na Educação Infantil.  Foi realizada uma revisão bibliográfica qualitativa e uma pesquisa de campo com 47 docentes, que responderam uma entrevista estruturada, cujas análises das respostas basearam-se nas concepções de: práticas pedagógicas, Pedagogia Histórico-Crítica e verificação do processo de ensino e aprendizagem. Dos resultados, houve o predomínio de: meios avaliativos enquadrados na objetividade (atividades impressas) e práticas pedagógicas como a contação de histórias. Quanto à Pedagogia Histórico-Crítica, cerca de cinco entrevistados apresentaram maior aproximação com perspectivas filosóficas e seis com perspectivas psicológicas da dimensão utilizada. Conclui-se que a teoria, embora compreendida por alguns docentes, não alcança plenamente o cotidiano escolar e práticas pedagógicas, que permanecem restritas por diretrizes legais. A realidade do ensino parece corroborar a ideia de que o sistema educacional limita o potencial da educação.
A política dos laboratórios de informática em escolas públicas: o PROINFO em interpretações docentes
Authors: Gomes Roberta Mirnas de Oliveira , Medeiros Emerson Augusto de , Santos Jean Mac Cole Tavares
Published: June 2024

O presente artigo tem por objetivo analisar como os professores concebem o Programa Nacional de Tecnologia Educacional (PROINFO), enquanto política educacional no contexto da escola pública. Em parâmetros metodológicos, utilizamos da abordagem qualitativa, a medida em que nos aproximamos, em meio à realização de entrevistas com quatro professores, atuando em duas escolas da rede estadual de ensino do Rio Grande do Norte, no referido programa. Como referencial teórico, a pesquisa recorreu aos estudos de Stephen Ball e seus colaboradores (1992; 2011; 2016), que nos permitiram investigar a proposta do PROINFO frente ao ciclo de políticas, sobretudo, observando as múltiplas demandas, discursos, significados, interpretações e atuações no contexto da prática escolar. Avaliamos que os docentes reconhecem a política do PROINFO pelo laboratório de informática. Contudo, a relação dos atores com o PROINFO ocorre em meio à criatividade e à responsabilidade ao depararem-se com uma estrutura fragilizada que desafia as práticas docentes.
Analisis Sentimen Pengguna Twitter dalam Pemilihan Presiden (PILPRES) 2024 dengan Menggunakan Algoritma K-Means
Authors: Amin Abdusy Syakur , Kurniadi Dede , Nurzaman Muhammad Zein , Nurfadillah Rifa Sri , Khoerunisa Sarah , Khaerunisa Nisrina , Ajiz Rafi Nurkholiq , Jembar Tegar Hanafi , Faisal Ridwan Nur
Published: June 2024

Salah satu bentuk penegakan demokrasi yang dilakukan oleh Negara Kesatuan Republik Indonesia yaitu melalui penyelenggaraan pemilihan presiden atau sering dikenal juga dengan istilah pilpres. yang diadakan setiap lima tahun sekali untuk memilih Presiden selanjutnya. Kemudian disamping itu, dalam era digital ini masyarakat semakin aktif menggunakan media sosial untuk menyampaikan pandangan, pendapat, dan sentimen mereka terkait dengan pemilihan presiden. Menjelang pilpres 2024 banyak kalangan seperti partai politik, tim sukses, buzzer, dan para pendukung memanfaatkan media sosial sebagai media berkampanye untuk meningkatkan popularitas dan elektabilitas bakal calonnya. Salah satu media sosial yang banyak digunakan dalam media promosi partai politik adalah twitter. Yang digunakan oleh orang-orang untuk mengirimkan berbagai komentar yang bisa bersifat positif atau negatif mengenai pemilihan tersebut. Terkadang, orang juga mengeluarkan pendapat yang bersifat hoaks sebelum atau selama pemilihan berlangsung. Mengingat komentar-komentar di Twitter saat ini sulit untuk dikategorikan sebagai positif atau negatif, diperlukan analisis sentimen guna memahami sikap publik terhadap pemilihan presiden tersebut. Penelitian ini bertujuan untuk mengevaluasi dokumen teks dan menentukan apakah dokumen tersebut memiliki orientasi sentimen positif atau negatif. selain itu metode yang digunakan yaitu K-Means untuk  melakukan clustering pada data. Hasil dari pembobotan ini berupa sentimen positif dan negatif. Data diambil dari Twitter mengenai pemilu presiden (pilpres)  2024  sebanyak 1015 data tweet.
PENGARUH VARIASI BASIS TERHADAP DAYA SIMPAN SALEP YANG MENGANDUNG EKSTRAK ETANOL DAUN BELIMBING WULUH (Averhoa bilimbi (L))
Authors: Lestari Tri Puji , Kurniawati Evi , Widyaningrum Esti Ambar
Published: June 2024

Starfruit wuluh, scientifically known as Averrhoa blimbi L., contains secondary metabolites such as flavonoids and tannins, which function as antibacterial agents. The extract of starfruit wuluh leaves is formulated into a ointment for easy application. The selection of a suitable ointment base is crucial to achieve the formulation's effectiveness. Understanding the influence of using different bases, specifically oil-in-water emulsion base and water-soluble ointment base, on the stability of ointment containing ethanol extract of starfruit wuluh leaves is the aim of this research. Stability testing is conducted for two weeks at room temperature. Physicochemical tests include organoleptic evaluation, homogeneity, adhesiveness, pH, and spreading ability of the formulation. The results indicate that the variation in the type of base does not affect organoleptic aspects, homogeneity, and pH during storage but does impact adhesiveness and spreading ability of the ointment containing starfruit wuluh leaf extract during storage
Implementasi Penggunaan Load Cell pada Mesin Peniris Minyak untuk Keripik Usus
Authors: Adimi Akbar Roisul , Fauziyah Mila , Dewatama Denda
Published: June 2024

Chicken ntestinal chips are processed foods that are often found in the general public. Intestinal chips are also an innovation from the community that processes waste from slaughtering chicken, namely intestines, into processed food. Processing of chicken intestinal chips determines the yield of these products so that chips can be produced which have a good shape and are not crushed, have a pleasant aroma, good taste, and have a brownish yellow and crunchy color. The process of making intestinal chips goes through several processes, one of which is the process of draining the oil. In the process of draining oil from intestinal chips it takes a long time. To shorten the time, an oil slicing machine is needed so that it does not require a long time but manual slicing can also be done. Drain speed control using the PID method. This method is expected to maintain the stability of the draining cycle. The results of the test obtained the value of Kp = 6, Ki = 2, Kd = 3 at the stirring speed control with a set point of 1400 RPM with the response results namely rise time of 16 s, delay time of 4 s, settling time of 66.5 s, Mp of 1.95%, peak time of 15.5 s, ESS of 1.95% and -2.25%.
Kontrol High Speed Extruder pada 3D Printer 2x2x2 Meter Berbasis MCU Bigtree
Authors: Resti Dyah Ayu Retno Palupi  , Setiawan Budhy , Pracoyo Agus
Published: June 2024

3D printer merupakan suatu inovasi terbaru dalam dunia teknologi. Industri manufaktur saat ini mengalami kemajuan pesat dan 3D printer menjadi salah satu alat yang berguna dalam industri tersebut. Alat ini dapat mencetak benda-benda tiga dimensi dari gambar CAD (Computer Aid Design). Di Indonesia, 3D printer digunakan untuk membuat prototype dengan cepat sehingga mempercepat pengembangan produk baru. Tahapan pembuatan prototype dengan 3D printer meliputi pengolahan file digital, proses slicer, dan G-Code, hingga menjadi objek benda nyata berbentuk 3D. Agar dapat bekerja dengan efisien, 3D printer membutuhkan extruder dengan kecepatan tinggi yang mampu mendorong lelehan plastik dengan cepat menuju nozzle, sehingga filamen plastik dapat meleleh keluar. Kecepatan extruder diatur oleh motor stepper dan menggunakan Bigtreetech dan Marlin Firmware untuk kontrol high speed extruder.
PROGRAMMABLE KONTROL UNTUK SEKUENSIAL PROSES PADA MESIN PEMBUATAN SABUN CUCI CAIR BERBASIS MIKROKONTROLER
Authors: Thaif_m Muhammadthaif , Setiawan Budhy , Gillang Al Azhar
Published: June 2024

Usaha mikro kecil dan menengah (UMKM) dengan potensi pengembangan internal di lembaga bina ummat Al-furqon yang sudah ada sebelumnya yaitu produksi sabun cuci cair. dimana usaha ini, santri dilibatkan dalam proses produksi sehingga, kapasitas produksi terbatas hanya 40 Liter.  oleh karna itu, proses produksi tidak efisien dan beresiko karena pelaku harus bersentuhan langsung dengan bahan asam dan basa kuat saat memproduksi sabun cuci cair.
Peningkatan potensi dilakukan dengan pembuatan mesin untuk proses pembuatan sabun cuci cair berkapasitas 100 Liter. Studi kali ini untuk mengoptimalkan produksi sabun cuci cair dengan mendesain, mengembangkan dan menerapkan Kontrol sekuensial pada miktrokontroller untuk proses pembuatan sabun cuci cair untuk mengontrol aKtuator berdasarkan hasil yang didapat pada penelitian ini mesin pembuatan sabun cuci cair dengan kontrol sekuensial proses dapat diimplementasikan. Dengan kontrol sekuensial tersebut proses pembuatan sabun cair lebih cepat dan efisien.
Implementasi Keamanan Box Penerima Paket Berbasis IoT
Authors: Jazilah Afwatul , Siradjuddin Indrazno , Gillang Al Azhar
Published: June 2024

Seiring dengan berkembangnya serta kemajuan teknologi memudahkan kita untuk dapat memenuhi berbagai kebutuhan hidup tanpa harus keluar rumah, yaitu dengan berbelanja secara online. Penggunaan jasa pengiriman juga meningkat drastis, namun tidak terlepas dari berbagai masalah yang terjadi dalam proses pengiriman barang. Salah satu masalah yang sering terjadi adalah penerima paket tidak berada di tempat. Pada kasus ini biasanya alternatif yang dilakukan oleh kurir seperti barang atau paket di lempar kedalam pagar atau di letakan di depan pintu rumah bahkan paket dititipkan ke tetangga. Berdasarkan permasalahan tersebut, maka dibuatlah alat untuk menerima paket yaitu membuat sebuah kotak (box) paket yang didalamnya dapat menampung paket-paket yang datang dengan menggunakan teknologi internet of things (IoT). Pemilik paket menginputkan nomor resi yang tertera pada paket menggunakan aplikasi telegram, setelah itu data tersebut akan disimpan pada mikrokontroler ESP32. Pada pintu paket dilengkapi dengan Doorlock agar pintu terkunci dan tidak dapat dibuka. Kemudian terdapat Motor Dc power window yang berfungsi untuk mengangkat pintu secara otomatis. Doorlock akan terbuka, ketika barcode pada paket discankan melalui barcode scanner GM65 yang ditandai dengan menyalanya pilot lamp berwarna hijau dan berbunyinya buzzer. Setelah itu, ketika paket telah masuk kedalam box maka pada aplikasi telegram akan mendapatkan sebuah pesan yang berisi tentang keterangan paket dengan nomor resi tersebut telah masuk.
Sistem Pengaman pada Smart Traktor Menggunakan Sensor GPS Berbasis IoT
Authors: Atok Ulloh  , Achmad Affandi  , Nurir Rohmah  , Fardany Faisal A. Labib , Catur Firmansah Aprilian
Published: June 2024

Penggunaan traktor merupakan salah satu perkembangan teknologi di bidang pertanian.  Adapun pengembangan pada traktor tangan yaitu Smart Tractor. Smart Tractor  merupakan traktor tangan yang telah dimodifikasi menjadi sistem kendali jarak jauh untuk mempermudah petani dalam membajak sawah. Namun dengan adanya teknologi tersebut mengakibatkan munculnya sebuah permasalahan baru seperti pencurian, penggunaan yang tidak sesuai lokasi dan lain sebagainya.  Untuk menjawab permasalahan tersebut, diperlukan sistem pengaman pada Smart Tractor. Sistem pengaman tersebut dibuat menggunakan Modul GPS sebagai sensor posisi, Node MCU ESP32 sebagai mikrokontroler, dan Relay. Sistem keamanan ini juga dilengkapi fitur (Internet of Thing) IoT melalui aplikasi thinger i.o. sehingga dapat diakses melalui smartphone. Data yang dikirimkan oleh Modul GPS adalah data titik koordinat latitude dan longitude serta gambar berupa maps yang ditampilkan pada dashboard thinger i.o. dan dapat diakses melalui smartphone. Hasil pembacaan Modul GPS divalidasi keakuratannya dengan pembacaan Google Maps. Sistem keamanan juga dilengkapi dengan Relay yang terhubung dengan aki. Tujuannya adalah untuk memutuskan aki apabila objek mengalami tindak pencurian. Relay juga dapat diakses menggunakan smartphone. Secara keseluruhan, sistem pengaman pada Smart Tractor ini memiliki hasil yang akurat, dibuktikan dengan nilai maksimal error yang kecil sebesar 0.0009% untuk data longitude dan 0.0012% untuk data latitude.
Simulasi Kontrol PID Ziegler-Nichols pada Sistem Penghancuran Batu dengan Motor Induksi 3 Fasa 20HP
Authors: Ramadhan Novalliansyah Ramadhan
Published: June 2024

Penelitian ini bertujuan untuk mengembangkan pengendalian otomatis pada mesin crusher batu koral menggunakan metode PID Ziegler-Nichols. Mesin crusher otomatis diatur dengan parameter PID yang dihasilkan dari metode Ziegler-Nichols, yaitu Kp=0.0957, Ki=0.9643, dan Kd=0.0024, dengan respons stabil setiap 1 detik setelah terjadi osilasi. Metode PID dipilih karena kemampuannya untuk mengontrol sistem secara otomatis dengan mengkombinasikan proporsional, integral, dan derivatif dari kesalahan sistem. Metode Ziegler-Nichols digunakan untuk menentukan parameter PID dengan melakukan uji respons terhadap sistem dan mengidentifikasi parameter yang optimal. Hasil penelitian menunjukkan bahwa metode PID Ziegler-Nichols memberikan pengendalian yang efisien dan stabil pada mesin crusher, meningkatkan kinerja dan keandalan proses penghancuran batu koral secara keseluruhan. Penelitian ini memberikan kontribusi penting dalam pengembangan sistem pengendalian otomatis untuk industri pemecahan batu koral yang membutuhkan tingkat presisi dan efisiensi yang tinggi.
Identifikasi Warna Bola dan SILO Menggunakan Metode You Only Look Once Pada Robot Pengambil Bola
Authors: Akmal Revanza Akmal Pradipta , Ryan Yudha Adhitya  , Zindhu Maulana Ahmad Putra  , Ii'Munadhif  , Mohammad Abu Jami’in  , Muhammad Khoirul Hasin
Published: June 2024

Robots are a modern technology that is experiencing very rapid growth. Robots also have several types, one type of robot is Robot Vision. Robot Vision uses image processing and computer vision in carrying out its tasks, including recognizing objects and controlling robot movements. Taking the concept from the ABU (Asia Pacific Broadcasting Union) robot contest in 2024 where the robot is required to be able to pick up balls with red and blue colors which are then inserted into a place called SILO. The detection method used in this study uses the YOLO (You Only Look Once) method with the YOLOv5 version. The reason for choosing the YOLOv5 version is because of its ability to be more accurate than previous versions and lighter to run than newer versions. From the results of this study, it was found that the confidence value for each object was quite high, which was 0.90. In addition, the precision value against recall for all classes gets a value of 0.991 or 99.1%. For the ball and SILO classes, the precision to recall value is 0.993 or 99.3%. So it can be concluded that this method has good value in terms of detection and accuracy
Penerapan Logika Fuzzy untuk Meningkatkan Efisiensi Pengembangbiakan Maggot Berbasis IoT
Authors: Pratama Novaly Arya , Sutrisno Imam , Rinanto Noorman
Published: June 2024

The 3R Waste Disposal Site "REJOAGUNG BERSERI" in Rejoagung Village is facing household waste management issues, particularly with organic waste contaminating the environment. The proposed solution is cultivating maggots (black soldier fly larvae) using organic waste. The challenges in maggot cultivation include natural predators, non-ideal environmental conditions, and a sensitive life cycle. Maggots are a high-protein feed source for livestock, containing 42% protein and possessing antimicrobial properties. In this research, we propose a monitoring and control system for maggot cultivation based on fuzzy logic in an IoT implementation to improve the efficiency of maggot cultivation. This system will optimize environmental conditions based on IoT sensor data such as temperature, humidity, and light intensity, thereby enhancing the quality and quantity of maggot production.
Determination of the activity of the fimF gene and its N-terminal domain disrupted mutant on biofilm formation and its contribution to the oxidative stress response in S. Typhimurium
Authors: Sürkaç Tuba Nur , Akçelik Nefise , Akçelik Mustafa
Published: June 2024

Fimbriae is an important virulence factor which plays a key role in cell attachment and colonization of the intestinal mucosa during an infection of Salmonella, a pathogen that causes gastroenteritis and systemic infection in humans. In S. Typhimurium, type 1 fimbriae production strengthens the oxidative stress response. This study aimed to determine the effectiveness of the fimF gene and its N-terminal domain on biofilm formation in S. Typhimurium and their contribution to the oxidative stress response. Before the experiments to prove whether the N-terminal domain of the FimF protein is the region that determines the mechanism and function of the fimF gene; only the N-terminal domain of the fimF gene was cloned behind the pBAD promoter. As a result of biofilm experiments on polystyrene surfaces, it was determined that the biofilm production capacity was reduced significantly in mutant strains in terms of fimF and dam genes (P<0.01). In the oxidative stress response experiment conducted in the presence of hydrogen peroxide (H2O2), it was determined that the mutant strains were more resistant to hydrogen peroxide than the wild-type strain, therefore Salmonella cells perceived the absence of Dam methylase enzyme and FimF protein as a critical internal stress condition and produced strong responses to these stress conditions. As a result of comparative analysis of the N-terminal domain cloned mutant strain with the wild-type, it was proven that the N-terminal domain of the protein in question acts as an adapter protein, due to its close similarities with the wild-type.
Radiographic cardiac indices for healthy New Zealand white rabbits: A reference interval study based on echocardiography
Authors: Kaya Mahir , Çetinkaya Mehmet Alper
Published: June 2024

This research was intended to identify reference intervals for the radiographic cardiac indices [vertebral heart scale (VHS), radiographic left atrial dimension (RLAD), and vertebral left atrial size (VLAS) of 58 healthy, adult New Zealand white rabbits based on echocardiography. The VHS, VLAS, and RLAD measurements were taken from contrast right lateral (R) and ventrodorsal (VD) thoracic radiographs. The correlations between these radiographic cardiac indices and echocardiographic parameters were then evaluated. The mean values with a reference interval were 7.94±0.31 vertebrae (v) (7.2-8.6 v) for R-VHS and 8.67±0.33 v (7.8-9.2 v) for VD-VHS. The median values with a reference interval were 1.5 v (1-2 v) for VLAS and 1 v (0.7-1.4 v) for RLAD. Body weight and gender had no effect on radiographic cardiac indices. There were positive correlations between all radiographic indices obtained from the R contrast radiographs and the echocardiographic parameters (rs≥0.421, P<0.0001). Excellent intraobserver agreement was determined for the radiographic measurement methods (intraclass correlation coefficients ≥0.818). The contrast thoracic radiography appears to represent a useful technique for the accurate determination of radiographic cardiac indices. The findings can be used as reference values for radiographic cardiac evaluation in both pet and laboratory rabbits.
KNOWLEDGE AND PERCEPTION OF UNVACCINATED PEOPLE TOWARDS COVID-19 VACCINE IN BOGOR, INDONESIA.
Authors: Widyastiwi Widyastiwi , Kusumanita Miselia
Published: June 2024

Background: The Indonesian government had been implementing a vaccination program since early 2021. Bogor Regency is one of the areas with a relatively low vaccination coverage compared to other areas in West Java. This phenomenon could be influenced by perceptions based on public knowledge of the Covid-19 vaccine.
Method: A cross-sectional study was conducted between May and July 2022. Unvaccinated people data was collected from Tamansari Public Health Center and the minimum sample size was determined using a 5% alpha error. Total 154 participants were enrolled in this study, with inclusion criteria: age >18 years old, had not received covid-19 vaccination, able to communicate, and willing to participate. Knowledge and perception were measured by a valid and reliable questionnaire. The correlation between knowledge and perception was analyzed using Spearman’s test, p<0,05 considered significant.
Objectives: This study aimed to evaluate the knowledge and perceptions of unvaccinated people towards Covid-19 vaccination in Tamansari Public Health Center working area, Bogor.
Result: The present study reported that 100% of participants were not willing to get vaccinated. Demographic data showed that the educational background of most of the participants is an elementary school (88,3%). Knowledge assessment towards Covid-19 vaccination showed that 63,6% of participants had poor knowledge of Covid-19, meanwhile, 32,5% and 3,9% of others had moderate and good knowledge, respectively. The majority of the participant had a negative perception towards Covid-19 vaccination (51,95% very negative, 38,96% negative). The top three negative perceptions opined by participants were Covid-19 vaccination would not affect their health during the pandemic era, hesitant about Covid-19 vaccine effectivity in preventing Covid-19, and afraid that Covid-19 vaccination could induce illness (scored 4,63; 4,49; and 4.47 of 5.00, respectively). ow level of knowledge significantly correlated with negative perception (p<0.05) towards Covid-19 vaccination with a correlation coefficient is 0.404 (moderate).
Conclusion: This study concluded that poor knowledge could affect the negative perception towards Covid-19 vaccination, which may be contributed as a barrier to the Covid-19 vaccination program. Our findings may provide information for the authorities and stakeholders to promote and improve knowledge and perceptions towards COVID-19 vaccination among unvaccinated people.
Prática educativa: trilha Serviços Ecossistêmicos da Árvore
Authors: Costa Clayton Angelo Silva
Published: June 2024

Estudos sinalizam o aumento do número de pessoas usando espaços públicos ao ar livre, principalmente após o período de isolamento social provocado pela doença do coronavírus 19 (COVID-19). O referido aumento requer, por parte do poder público, a potencialização do planejamento ambiental para parques urbanos, com reflexo no bem-estar mental das pessoas, a partir de propostas de práticas educativas de cunho socioambiental. As práticas podem envolver os serviços ecossistêmicos, o ser humano, a percepção e a Educação Ambiental. Trata-se de uma pesquisa qualitativa com o objetivo de apresentar as etapas de um planejamento ambiental, envolvendo os serviços ecossistêmicos das árvores, o ser humano, a percepção e a Educação Ambiental para trilhas em Espaços Verdes Urbanos (EVU).
Análise textual discursiva e a Educação Ambiental
Authors: França Andreia Castro de Sousa , Nascimento Jackgrayce Dutra , Firmo Wellyson da Cunha Araújo
Published: June 2024

Este artigo ressalta a importância da Educação Ambiental (EA) e seu compreender sobre o olhar da Análise Textual Discursiva (ATD), e teve como objetivo principal mapear os trabalhos publicados no portal da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), de 2012 a 2022. Para isso, utilizou-se uma metodologia de abordagem qualitativa, com características de pesquisa descritiva. Conclui-se que existem poucos trabalhos científicos que envolvam o tema ATD e EA, o que faz refletir sobre a sua recente perda de espaço no currículo da Educação Básica, e que o compreender sobre a EA precisa de mais força e mais pesquisas relacionadas com a sua importância como formadora e transformadora crítica do cidadão.
Os caminhos para uma Educação Ambiental com hortas escolares: um estudo de caso em Caxias do Sul (RS)
Authors: Righi Eléia , Linhar William , Fonseca Fabiana Lazzerini da , Drawanz Bruna Bento , Trentin Carline
Published: June 2024

Esse trabalho teve por objetivo trazer os caminhos para uma Educação Ambiental com hortas escolares urbanas. O local se localiza no Instituto Estadual de Educação Cristóvão de Mendoza, localizado em Caxias do Sul (RS). Esse projeto de extensão está no seu quarto ano de implementação e assume também, responsabilidade ambiental e social, propiciando o resgate dos saberes dos estudantes, em relação aos conteúdos que se pretende trabalhar, constituindo-se o ponto de partida para o processo de ensino e aprendizagem.