bluuebunny/crossref_metadata_2025 huggingface dataset:
Nilai Tukar Nelayan Kabupaten Situbondo
Authors: Pahlewi Anita Diah , Ramli Ramli , Novianti Vita
Published: February 2024

Nelayan sangat tergantung terhadap musim. Pengukuran terhadap  kesejahteraan  nelayan  membutuhkan  indikator  yang  secara cepat  dan  tepat  untuk  melihat  gambaran  kesejahteraan  yang  telah  dicapai.  Salah  satu indikator  yang  dipercaya  dapat  digunakan  untuk melihat  kesejahteraan  rumah  tangga  adalah indikator Nilai Tukar  Nelayan (NTN). Tujuan dari penelitian Nilai Tukar Nelayan ini adalah mengetahui karakteristik nelayan dan pencapaian Nilai Tukar Nelayan di Kabupaten Situbondo sehingga dapat dimanfaatkan untuk memberikan masukan dalam formulasi sasaran dan penyusunan kebijakan untuk meningkatkan kesejahteraan nelayan. Metode yang digunakan dalam penelitian Nilai Tukar Nelayan ini ialah survei. Jumlah responden dalam Kajian Nilai Tukar Nelayan (NTN) ini sebanyak 189 responden. Karakteristik responden dalam kajian ini meliputi kelompok umur dan tingkat pendidikan. Karakteristik responden nelayan berdasarkan kelompok umur terdiri dari 43% responden nelayan berada pada kelompok umur 41 – 50 tahun, 22% kelompok umur 30-40 tahun, 20% kelompok umur dibawah 30 tahun dan paling sedikit 15% kelompok umur 51-60 tahun. Hasil analisis karakteristik responden nelayan berdasarkan Tingkat Pendidikan, mayoritas responden merupakan  lulusan Sekolah Dasar (SD) kebawah yaitu sebanyak 69%, 23% lulusan Sekolah Lanjutan Tingkat Pertama (SLTP) dan hanya 8% yang pernah mengenyam pendidikan Sekolah Lanjutan Tingkat  Atas (SLTA). Nilai NTN Kabupaten Situbondo periode Januari – Oktober 2022 adalah 1,043 atau nilai NTN tersebut berada disekitar angka satu yang berarti keluarga nelayan di Kabupaten Situbondo pada Tahun 2022 hanya mampu memenuhi kebutuhan hidupnya dan masuk kategori rentan miskin serta belum mampu mengkonsumsi kebutuhan sekunder atau tersier, untuk menabung dalam bentuk investasi barang.
Akurasi Pengukuran Gelombang Di Depan Model Pemecah Gelombang Terapung
Authors: Rahman Sabaruddin , Timang Novrian Yosua , Baeda Achmad Yasir
Published: February 2024

Gelombang laut merupakan pergerakan dari air laut di permukaan dengan gerakan naik ataupun turun yang berbentuk sama seperti garis sinusoidal, yang dapat timbul diakibatkan oleh gaya pembangkit pada permukaan laut dengan macampembangkit gelombang laut oleh angin, gaya tarik menarik antara bumi, bulan dan matahari, gempa dan terakhir olehgerakan kapal. Gelombang reguler diuji dalam flume gelombang dengan panjang 25 m, lebar 1 m dan kedalaman 1,2 myang dilengkapi dengan generator gelombang tipe flap. Penyerap gelombang di ujung lainnya dibangun dari gundukanbatu. Delapan titik pengukur gelombang (HR Wallingford 8 saluran) ditempatkan bersama dengan panjang gelombang.Probe gelombang 1-5 diatur pada jarak 0,1L sedangkan 5-8 diatur pada 0,2L. Pembangkit gelombang kemudianmenghasilkan fluktuasi muka air yang meningkat hingga mencapai ketinggian gelombang yang diinginkan. Setelahbeberapa gelombang datang, gelombang pantul kemudian menurunkan fluktuasi muka air hingga mencapai kondisigelombang stabil (yang bentuk dan tinggi puncaknya relative sama) yang menunjukkan bahwa gelombang yangdihasilkan adalah gelombang linear. Metode R2 digunakan untuk mengevaluasi akurasi pengukuran gelombang, bahwametode dua titik dengan jarak pengukur gelombang 0,2L adalah metode terbaik untuk mengukur tinggi gelombang.Keduametode tersebut dibandingkan dengan metode umum untuk mendapatkan yang sesuai untuk setiap kasus. Gelombangyang dibangkitkan cenderung nonlinier dengan bertambahnya tinggi gelombang. Keakuratan berkurang karena nonliniergelombang yang dihasilkan. Kinerja pembangkit gelombang dapat ditingkatkan dengan mengurangi refleksi gelombang.Ada pengaruh jarak pengukur gelombang terhadap akurasi pengukuran tinggi gelombang. Akurasi yang baik dapatdicapai pada jarak probe gelombang 0,2L untuk metode dua titik dan tiga titik.
A Systematic Review on Employee Performance: Scopus Database
Authors:   Research Scholar, Department of Commerce, MaharshiDayanand University, Rohtak, Harayana, India, SAINI RAM RATTAN ,   Professor, Department of Commerce, MaharshiDayanand University, Rohtak, Harayana, India
Published: February 2024

According to recent HR studies, employees play vital role to the success of organizations. In recent years, employee performance has gained popularity as a research issue in HR studies, attracted researchers to pinpoint its various determinants. To identify the areas where employee performance could be improved, researchers have undertaken a number of studies over a decade on the different perspectives of performance. The objective of this review is to discuss the dimensions of employee performance, recent advancements in the employee performance areas, the influence of a few key factors on employee performance, as well as its prospects in improving employee performance.
Peran Pendidikan Agama Kristen dalam Memerangi Radikalisme dan Ekstremisme: Menumbuhkan Cinta, Perdamaian, dan Rasa Hormat
Authors: Messakh Jefrit Johanis , Boiliu Esti Regina
Published: February 2024

The spread of radicalism and extremism has become a global concern in recent decades. Issues regarding radicalism and extremism continue to develop in a flurry of problems. This requires the active role of Christian Religious Education to be carried out in a structured manner in order to be able to overcome this challenge by cultivating love, peace and respect. The purpose of this study is to describe the role of Christian Religious Education in fighting radicalism and extremism. The method used in this research is literature study. The result of this research is that Christian religious education can be a powerful force in fighting radicalism and extremism by instilling universal values such as love, peace and respect for fellow human beings. Christian Religious Education also plays a role in developing a deep understanding of Christian teachings which include values such as love for others, forgiveness, understanding, and tolerance. Christian Religious Education must build intercultural skills, and integrate social issues in the Christian Religious Education curriculum.
GAMBARAN MAKNA HIDUP PADA PSK REMAJA YANG MENJALANI REHABILITAS DI PSKW ANDAM DEWI SOLOK
Authors: Zhafran Ezra Akbar  , Nurmina
Published: February 2024

Prostitusi pada remaja sudah sangat mengkhawatirkan karena banyaknya kasus eksploitasi remaja. PSK remaja yang menjalani rehabilitasi karena ditangkap Satuan Polisi Pamong Praja (Satpol PP) akan menjadi sumber tekanan pada kehidupannya, terutama jika pelaku PSK masih remaja mereka cenderung lebih rentan mengalami berbagai dampak emosional dan psikologis yang negatif akibat hukuman seperti merasa bersalah, hilangnya kebebasan, adanya perasaan malu, sanksi ekonomi dan akan mempengaruhi penyesuaian fisik tetapi juga psikologis individu. Penelitian ini  bertujuan untuk melihat gambaran makna hidup pada PSK remaja yang menjalani rehabilitas di PSKW Andam Dewi Solok. Penelitian ini menggunakan pendekatan fenomenologis dengan metode kualitatif. Pengumpulan data dilakukan dengan menggunakan teknik wawancara semi terstruktur kepada 2 (dua) orang subjek yang merupakan PSK remaja yang sedang menjalani rehabilitas di PSKW Andam Dewi Solok. Teknik analisis data pada penelitian ini menggunakan teknik Interpretative Phenomenological Analysis (IPA). Hasil penelitian ini ditemukan bahwa subjek PSK remaja yang sedang menjalani rehabilitas dapat mencapai 5 (lima) tahapan dalam penemuan makna hidup yang dikemukakan oleh Bastaman. Kemudian, faktor yang mempengaruhi makna hidup pada penelitian ini adalah pemahaman diri, berperilaku positif, pengakraban hubungan, pendalaman catur nilai, dan ibadah.
Hubungan Optimisme dengan Work Readiness dalam Menghadapi Persaingan di Dunia Kerja Pada Siswa Sekolah Menengah Kejuruan (SMK) Negeri di Kota Padang
Authors: Syafrin Alhakim Hidayatullah , Dwatra Free Dirga , Mardianto  , Nio Suci Rahma
Published: February 2024

Penelitian ini bertujuan untuk mengetahui Hubungan Optimisme dengan Work Readiness dalam menghadapi persaingan di dunia kerja pada Siswa Kejuruan Menengah (SMK) di Negeri kota Padang. Jenis penelitian ini adalah penelitian kuantitatif dengan berbasis survei. Populasi penelitian adalah siswa SMK N di kota Padang. Subjek penelitian merupakan siswa SMKN kelas 12 di kota Padang yang berjumlah 238 siswa. Alat ukur penelitian ini menggunakan skala optimisme dan work Readiness. Teknik analisis data yang digunakan yaitu correlation product moment untuk menguji adanya hubungan antar variabel. Hasil uji hipotesis ini menunjukkan koefisien korelasi r=0,199 dengan signifikansi p = 0,002 (p<,0,05). Hal ini menandakan bahwa H0 ditolak dan Ha diterima. Hal ini menunjukkan bahwa terdapat hubungan positif yang signifikan antara optimisme dengan work readiness dalam menghadapi persaingan di dunia kerja pada siswa Sekolah Menengah Kejuruan (SMK) Negeri di kota Padang.
Appréciation de la gestion des ressources humaines à la société nationale d’électricité
Authors: MUKADI LUBOYA Roger
Published: February 2024

Dans une organisation professionnelle, la bonne gestion des ressources humaines conduit naturellement au succès. Cette étude réalisée révèle que SNEL respecte les prescrits du code de travail ainsi que la convention collective, bien que dirigée par des politiciens et non des managers. L’appréciation qui s’y dégage est mitigée : Mots clés : appréciation ; gestion de ressources humaines ; SNEL.
HARMONISASI KEBERAGAMAN: PENDEKATAN LIVING QUR'AN TERHADAP TAFSIR WAHBAH AZ-ZUHAYLI TENTANG AYAT-AYAT TOLERANSI DALAM KOMUNITAS
Authors: AZILA FITRIA , ZULYADAIN
Published: February 2024

Penelitian ini bertujuan untuk mengeksplorasi dinamika masyarakat di Dusun Karang Pangsor, Desa Pemenang Barat, yang melibatkan dua agama utama, Islam dan Hindu. Meskipun adanya perbedaan keyakinan, masyarakat tersebut berhasil mempertahankan harmoni sosial, menciptakan lingkungan yang aman, tenteram, dan damai. Fokus utama penelitian ini adalah pada implementasi penafsiran Wahbah Az-Zuhayli terhadap ayat-ayat toleransi antar umat beragama, dengan menggunakan pendekatan Living Qur'an. Metode penelitian yang digunakan bersifat kualitatif, mengusung pendekatan penelitian lapangan, atau dikenal sebagai penelitian Living Qur'an, yang mengamati praktik implementasi al-Qur'an dalam konteks masyarakat. Pengumpulan data dilakukan melalui observasi, wawancara, dan dokumentasi sebagai data primer, dan mendukungnya dengan referensi dari buku, jurnal, makalah, kitab tafsir, serta dokumen resmi sebagai data sekunder. Hasil penelitian mengindikasikan bahwa (1) ayat-ayat tentang toleransi mendorong sikap penghormatan, pemahaman, dan saling menghargai antar umat beragama, yang bertujuan untuk mencapai kerukunan dan perdamaian, dan (2) masyarakat di Dusun Karang Pangsor berhasil menerapkan sikap toleransi sesuai dengan interpretasi Wahbah Az-Zuhayli, yang diwujudkan dalam saling menghormati dan menghargai perbedaan agama sebagai bentuk praktik Living Qur'an.
Characterization and Delineation of Potential Evaporite Geohazards Using Electrical Resistivity Methods along FM 2185, Culberson County, Texas
Authors: Perkins Lenora D. , Stafford Kevin W. , Brown Wesley A.
Published: February 2024

Extensive karst development within the Delaware Basin of West Texas and southeastern New Mexico poses a significant threat to infrastructure. Dissolution of regional evaporite strata have led to karst geohazards including sinkholes, subsidence features, and caves. The study area is located within the Gypsum Plain in Culberson County, Texas, and includes outcrops of Permian Castile and Rustler strata that host gypsum karst. Land reconnaissance surveys conducted during summer of 2019 documented numerous surface karst features proximal to Farm to Market Road 2185 (FM 2185). In combination with traditional survey techniques, electrical resistivity methods were used to delineate karst features along a 48 km segment of FM 2185. Capacitively-coupled resistivity (CCR) and direct-current resistivity (DCR) methods were used to characterize evaporite karst features that do not manifest surficially but pose potential geohazard concerns. CCR data were acquired using the Geometrics OhmMapper G–858 resistivity system, which uses a dipole-dipole configuration composed of five receivers connected by 2.5 m coaxial cables and a transmitter offset of 2.5 m. In combination with the medium analyzed, this geometric configuration enabled resistivity soundings up to 2.5 m deep. DCR data was collected with a SuperSting (R8/IP) multi-electrode earth resistivity meter using 112 electrodes with 2 m spacing and a dipole-dipole array configuration. This enabled a depth of investigation of up to 25 m. Data were processed using Advanced Geosciences Inc.’s (AGI’s) EarthImager 2D software and used to delineate and characterize karst-related geohazards in the shallow subsurface within the study area. Five sites are presented to demonstrate karst variability and electrical resistivity method effectiveness in geohazard detection in gypsum strata.
PENERAPAN ROUTE PELAYARAN KAPAL PENYEBERANGAN MERAK-BAKAUHENI DAN ARAH SEBALIKNYA TERHADAP TRAFFIC SEPARATION SCHEME (TSS) SELAT SUNDA
Authors: Nursyamsu  , Joko Sulistiono  , Sandi Wahyu Prabowo
Published: February 2024

Pada dunia pelayaran, keselamatan kapal untuk mencapai pelabuhan

tujuan mempakan hal yang wajib terwujud agar misi transportasi orang maupun

barang dapat terpenulii. Keselamatan pelayaran mempakan keseluruhan proses

yang hams dijalani dari kapal sandar, kapal memuat, kapal berlayar ke pelabuhan

tujuan sampai kapal itu membongkar muatannya.

Pada saat kapal berlayar tentunya sangat diperlukan navigator yang

memiliki kompetensi untuk melayarkan kapal sesuai dengan ukuran dan daerah

pelayaran. Navigator akan memahami prosedur, ketentuan peraturan pencegahan

tubrukan di laut dengan ketentuan penunjang lainnya. Di dalam peraturan P2TL

aturan 10 tentang bagan pemisah lalu lintas atau Traffic Separation Scheme (TSS)

dibuat untuk membentuk alur pelayaran dengan arah yang sama sehingga dapat

mengontrol alur pelayaran kapal di perairan tersebut.

Indonesia mempakan negara kepulauan pertama di dunia yang memiliki

bagan pemisahan lalu lintas berdasarkan hasil keputusan sidang Plenary

International Maritime Organization (IMO) Sub Committee Navigation

Communication and Search and Rescue (NCSR).

Dikarenakan ramainya perairan ini maka kapal yang melintasi hams

berlayar dengan hati-hati serta menggunakan secara maksimal peralatan navigasi

yang ada. Kapal yang paling sering menggunakan jalur atau melintasi jalur

tersebut adalah kapal penyeberangan. Tentunya kapal-kapal ini harus senantiasa

menjalakan semua ketentuan jika berlayar pada jalur TSS selat sunda ini baik

penggunaan alur yang benar dan peralatan navigasi penunjang yang dibutuhkan

demi keselamatan pelayarannya.

Dalam penelitian ini menitik beratkan kepada penerapan peraturan TSS

bagi kapal penyeberangan dan peran dari VTS selat Sunda dalam mengontrol

kepatuhan kapal terhadap TSS ini.
Optimalisasi penerapan keselamatan kerja dalam upaya pencegahan kecelakaan kru pada saat bekerja di Kapal MV. Cepat
Authors: Rikardo Dapid , Saleh Sahar , Nurrahman Muhammad Hanief
Published: February 2024

Teknologi peralatan di atas kapal telah berkembang semakin canggih dan modern. Perkembangan teknologi tersebut tidak semata-mata dapat menghindarkan para awak kapal dari kecelakaan saat bekerja. Ada beberapa faktor utama penyebab terjadinya kecelakaan saat bekerja, seperti faktor internal dan faktor eksternal. Penelitian ini bertujuan untuk mengetahui optimalisasi penerapan keselamatan kerja di atas kapal. Pemerintah menerapkan peraturan menyangkut keselamatan dan keamanan kerja di atas kapal. Organisasi internasional seperti International Maritime Organization (IMO) juga menekankan kepada seluruh perusahaan di dunia internasional untuk memperhatikan keselamatan para awak kapal. Penelitian ini dilakukan di atas kapal semen dan dilaksanakan selama 12 bulan. Penelitian ini termasuk dalam penelitian kualitatif menggunakan metode wawancara dan observasi. Populasi dalam penelitian ini berjumlah 22 orang, dengan jumlah sampel sebanyak 9 orang. Hasil dari penelitian ini menunjukkan bahwa awak kapal telah menjalankan prosedur tentang keselamatan dengan baik, serta memastikan bahwa alat keselamatan yang ada selalu dalam kondisi lengkap dan baik.
The equipment technology on board ships has developed increasingly sophisticated and modern. The development of this technology can not only prevent ships from accidents while working. Several main factors cause workplace accidents, such as internal and external factors. This research aims to determine the optimization of the implementation of work safety on ships. The government implements regulations regarding work safety and security on ships. International organizations such as the International Maritime Organization (IMO) also put pressure on all companies in the global world to pay attention to the safety of ship crews. This research was conducted on a cement ship for 12 months. This research is included in qualitative research using interview and observation methods. The population in this study was 22 people, with a sample size of 9 people. The research results show that the ship's crew has carried out safety procedures well and ensured that the existing safety equipment is always in complete and good condition.
Development of Leaf Area Model in Chokeberry Plant Grown in Different Irrigation Water Quality
Authors: AKYÜZ Ayşe , CEMEK Bilal
Published: February 2024

Chokeberry is a berry fruit species that has grown in the world in a few decades, and it is used in many fields, especially in the pharmaceutical industry. There needs to be a study examining the relationship between leaf area and irrigation water quality in this species, whose cultivation has started to increase. In this study, which was carried out between 2021 and 2022, the effects of irrigation water quality on leaf area in 1-year-old chokeberry plants of the 'Viking' variety grown in peat and soil media were determined. Irrigation water with 0.65 dS m-1 (Control), 2dS m-1, 4dS m-1, 8dS m-1, and 10dS m-1 electrical conductivity were used in the study. A model was developed in this study to estimate leaf area (LA) using leaf width (W) and leaf length (L) values to determine leaf area. The proposed prediction model was determined as "LA=2.86+4.448×W+0.33×L2-1.496×L " (R2= 0.99). Three-dimensional graphs of the developed models were drawn, and the changes in leaf width, length, and leaf area values against irrigation water salinity were determined. As a result, it was determined that there was a negative relationship between the electrical conductivity of irrigation water and leaf width, length, and area values.
Variations on the theme of "ballet" in the works of Eric Satie
Authors: Porubina Marina Vladimirovna
Published: February 2024

The work of Erik Satie, his value assessment, as well as the peculiarities of the author's non-normative artistic thinking have repeatedly become the subject of musicological discussions, but still a number of his artistic discoveries in different genre areas remain out of the researchers' field of vision. The proposed article analyzes the French composer's ballet work, which became a space of experimentation in the process of searching for a new image of a musical-choreographic performance. The material of the study includes not only the odious "Parade", which became a manifesto of the "new art", but also four other works by Erik Satie in the genre of ballet, without the study of which it is impossible to draw a complete picture of this sphere ("Uspud", "The Adventures of Mercury", "Eccentric Beauty", "The Spectacle is Canceled"). Their consideration from the point of view of the evolution of the author's approach to the creation of music for a ballet performance, as well as in the aspect of revealing content-semantic, compositional-dramaturgical and stylistic innovations, is the subject of research in this article. In the process of studying the problem, a comprehensive approach is applied, combining comparative and cultural-historical methods with theoretical and analytical tools of musicology. In the course of the analysis, the author comes to the conclusion that all components of the artistic whole of a ballet performance undergo transformation. At the narrative and semantic level, there is a gradual rejection of the traditional libretto, procedurally revealing the fabula of what is happening on stage, in favor of a small script plan, often without development and cause-and-effect relationships between episodes. The compositional and dramaturgical solution of the ballets is based on the suite, which is the root of the genre, but interpreted in a modified form, with the active involvement of combinatorics and montage. The musical and stylistic appearance of the performances is also often determined by an "anti-academic" concept characteristic not only of this genre, but also of Erik Satie's work in general. The sound space of the composer's ballets is highly heterogeneous and represents a mix of academic musical traditions with the culture of everyday life, both musical (music hall, cabaret, jazz) and extra-musical (the use of everyday objects reproducing the noise of the urban environment in the score of Parade).
The Influence of the Green Hospital Implementation Policy on the Energy Saving Behavior of XYZ Hospital Employees Using the Theory of Planned Behavior Approach
Authors: Asmawati Dika , Adisasmito Wiku Bakti Bawono
Published: February 2024

This research uses the Theory of Planned Behavior as the theoretical framework to analyze the relationship between the implementation of green hospital policy and energy-saving behaviors of employees in the hospital environment. The study's sample consists of 150 permanent employees, and the statistical data are analyzed using the Structural Equation Modeling-Partial Least Square (SEM-PLS) technique. The analysis results indicate that implementing the green hospital policy influences the supportive factors of behavior: attitudes, subjective norms, and perceived behavioral control. However, the tests also reveal that subjective norms do not positively correlate with the energy-saving behaviors of employees at the hospital. The mediation analysis shows that attitudes and perceived behavioral control mediate between the green hospital policy and the intention to save energy. In contrast, subjective norms do not significantly mediate the relationship. As organizations strive for sustainability, these insights offer valuable guidance for refining policies and interventions that promote energy conservation among management and hospital staff.
Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing
Authors: Zhang Aixin , Jin Lei , Yao Shenqin , Matsuyama Makoto , van Velthoven Cindy TJ , Sullivan Heather Anne , Sun Na , Kellis Manolis , Tasic Bosiljka , Wickersham Ian , Chen Xiaoyin
Published: February 2024

Mapping the connectivity of diverse neuronal types provides the foundation for understanding the structure and function of neural circuits. High-throughput and low-cost neuroanatomical techniques based on RNA barcode sequencing have the potential to map circuits at cellular resolution and a brain-wide scale, but existing Sindbis virus-based techniques can only map long-range projections using anterograde tracing approaches. Rabies virus can complement anterograde tracing approaches by enabling either retrograde labeling of projection neurons or monosynaptic tracing of direct inputs to genetically targeted postsynaptic neurons. However, barcoded rabies virus has so far been only used to map non-neuronal cellular interactions in vivo and synaptic connectivity of cultured neurons. Here we combine barcoded rabies virus with single-cell and in situ sequencing to perform retrograde labeling and transsynaptic labeling in the mouse brain. We sequenced 96 retrogradely labeled cells and 295 transsynaptically labeled cells using single-cell RNA-seq, and 4130 retrogradely labeled cells and 2914 transsynaptically labeled cells in situ. We found that the transcriptomic identities of rabies virus-infected cells can be robustly identified using both single-cell RNA-seq and in situ sequencing. By associating gene expression with connectivity inferred from barcode sequencing, we distinguished long-range projecting cortical cell types from multiple cortical areas and identified cell types with converging or diverging synaptic connectivity. Combining in situ sequencing with barcoded rabies virus complements existing sequencing-based neuroanatomical techniques and provides a potential path for mapping synaptic connectivity of neuronal types at scale.
Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3
Authors: Hathaway Nicholas J , Kim Isaac E , WernsmanYoung Neeva , Hui Sin Ting , Crudale Rebecca , Liang Emily Y , Nixon Christian P , Giesbrecht David , Juliano Jonathan J , Parr Jonathan B , Bailey Jeffrey A
Published: February 2024

Most malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and PfHRP3, but deletions of pfhrp2 and phfrp3 genes make parasites undetectable by RDTs. We analyzed 19,313 public whole-genome-sequenced P. falciparum field samples to understand these deletions better. Pfhrp2 deletion only occurred by chromosomal breakage with subsequent telomere healing. Pfhrp3 deletions involved loss from pfhrp3 to the telomere and showed three patterns: no other associated rearrangement with evidence of telomere healing at breakpoint (Asia; Pattern 13-TARE1); associated with duplication of a chromosome 5 segment containing multidrug-resistant-1 gene (Asia; Pattern 13-5++); and most commonly, associated with duplication of a chromosome 11 segment (Americas/Africa; Pattern 13-11++). We confirmed a 13–11 hybrid chromosome with long-read sequencing, consistent with a translocation product arising from recombination between large interchromosomal ribosome-containing segmental duplications. Within most 13-11++ parasites, the duplicated chromosome 11 segments were identical. Across parasites, multiple distinct haplotype groupings were consistent with emergence due to clonal expansion of progeny from intrastrain meiotic recombination. Together, these observations suggest negative selection normally removes 13-11++pfhrp3 deletions, and specific conditions are needed for their emergence and spread including low transmission, findings that can help refine surveillance strategies.
Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation
Authors: Sperry Megan M , Charrez Berenice , Fotowat Haleh , Gardner Erica , Pilobello Kanoelani , Izadifar Zohreh , Lin Tiffany , Kuelker Abigail , Kaki Sahith , Lewandowski Michael , Lightbown Shanda , Martinez Ramses , Marquez Susan , Moore Joel , Plaza-Oliver Maria , Sesay Adama M , Shcherbina Kostyantyn , Sheehan Katherine , Takeda Takako , Del Campo Daniela , Andrijauskaite Kristina , Cisneros Exal , Lopez Riley , Cano Isabella , Maxwell Zachary , Jessop Israel , Veraza Rafa , Bunegin Leon , Percival Thomas J , Yracheta Jaclyn , Pena Jorge J , Wood Diandra M , Homas Zachary T , Hinshaw Cody J , Cox-Hinshaw Jennifer , Parry Olivia G , Sleeter Justin J , Weitzel Erik K , Levin Michael , Super Michael , Novak Richard , Ingber Donald E
Published: February 2024

Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially for organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screening of metabolism, mobility, and development in Xenopus, we identified an existing drug, SNC80, that rapidly and reversibly slows biochemical and metabolic activities while preserving cell and tissue viability. Although SNC80 was developed as a delta opioid receptor activator, we discovered that its ability to slow metabolism is independent of its opioid modulating activity as a novel SNC80 analog (WB3) with almost 1000 times less delta opioid receptor binding activity is equally active. Metabolic suppression was also achieved using SNC80 in microfluidic human organs-on-chips, as well as in explanted whole porcine hearts and limbs, demonstrating the cross-species relevance of this approach and potential clinical relevance for surgical transplantation. Pharmacological induction of physiological slowing in combination with organ perfusion transport systems may offer a new therapeutic approach for tissue and organ preservation for transplantation, trauma management, and enhancing patient survival in remote and low-resource locations.
A Cross-sectional Study to Assess Bacteriological Quality of Fresh Vegetable Salads and Associated Risk Factors in Food Service Establishments in Mwanza City
Authors: Magambo Juma Morigo John , Majaliwa Nuria , Kussaga Jamal B.
Published: February 2024

This study examined the bacteriological quality of fresh vegetable salads and associated risk factors in restaurants and street food vendors in Nyamagana and Ilemela municipalities, Mwanza City, Tanzania. Thirty samples of vegetable salads (i.e., Kachumbari), along with 30 swabs from hands and chopping boards, were collected and analyzed. High contamination levels exceeding acceptable limits were observed with total bacterial counts, S. aureus, and E. coli ranging from 3.6 to 6.7 log CFU/g. All Kachumbari samples (100%) were unsatisfactory, and 17 (56.7%) had unsatisfactory E. coli levels. Moreover, 22 samples (73.3%) had unsatisfactory S. aureus levels, and 10 samples (33.3%) showed unsatisfactory Salmonella spp. contamination. Further, Kachumbari from street food vending sites had a significantly (p < 0.05) higher TBC mean value (6.5 ± 0.3 log CFU/g) than the one from restaurants (5.2 ± 0.6 log CFU/g). On the other hand, chopping boards and hands had high total counts ranging from 3.5 to 4.7 log CFU.cm-2. Also, the type of chopping board was significantly related to the S. aureus contamination levels in the Kachumbari salads (p < 0.05). The presence of both hygiene indicator microorganisms and pathogens indicates a potential public health risk associated with the consumption of Kachumbari. Urgent intervention measures are required to enhance handling practices, personal hygiene, and overall safety throughout the food value chain, thus ensuring the quality and safety of vegetable salads in food service establishments.
The Influence of the Demographic Factors of Nigerian Dental Practitioners on their Perception of Accelerated Orthodontics
Authors: Okino Benjamin O. , Okino Chikamaram O. , Ututu Chinyere , Orikpete Mariam , Onyeaso Chukwudi O.
Published: February 2024

Background: Although there are many studies on the reviving subject of accelerated orthodontics, there is paucity of information on the factors that could influence a dental practitioner’s perception of the concept.

Aim: To investigate the influence of the demographic factors of some Nigerian dental practitioners on their perception of accelerated orthodontics.

Materials and Methods: Electronic and physical methods of surveying the Nigerian dental practitioners were carried out between January and June 2023. The contents of the questionnaire involving their perception of accelerated orthodontics were analysed for associations with the participants’ demographics, using the IBM SPSS version 25. Descriptive statistics, the ANOVA and independent t-test were used with the significance level set at P< .05.

Results: No statistically significant associations were found between the participants’ demographics and their perception of accelerated orthodontics (P > .05), except for age group of 40-49 that revealed significant association with the local use of some medications intraorally (P<.05).

Conclusion/Recommendation: Generally, the participants’ demographics did not have significant influence on their perception of accelerated orthodontics, and further related studies are advocated.
Classification of Java Cities/Regencies Based on Human Development Index Using Discriminant Analysis and Naïve Bayes Classifier
Authors: Astrianka Orryza Oky , Efendi Achmad
Published: February 2024

Aims: This research aims at grouping of cities/regencies on the island of Java, where the central government as well as the most densely populated island in Indonesia, using linear discriminant analysis (LDA) and Naïve Bayes Classifier (NBC).

Study Design: Quantitative design.

Place and Duration of Study: Sample: The data used in this study is secondary data from the Indonesian Central Statistics Agency (Badan Pusat Statistik, BPS) regarding the 2022 Human Development Index (HDI) from 119 cities/regencies on the island of Java. The data used are four HDI indicators as independent variables (long and healthy living, knowledge, and the dimensions of decent living standards) and the HDI value as the dependent variable.

Methodology: The grouping was carried out using LDA and NBC. LDA is a type of multivariate analysis used in the dependency method where the relationship between variables can be distinguished between the independent variable and the dependent variable. It aims at obtaining discriminant function equations to group cases into certain groups and to determine differences between groups based on independent variables. Meanwhile, the NBC method is a simple probability-based prediction technique based on the application of Bayes' theorem (Bayes' rule) with a strong assumption of independence.

Results: Both LDA and NBC can be used for prediction and classification. Based on the results of the discriminant analysis, three discriminant functions were formed to group cities/regencies on the island of Java into three HDI groups. In the NBC analysis, the prior probability value for the very high category HDI group was 0.211, the high category HDI group was 0.606, and the medium category HDI group was 0.183. The research results show that LDA is better than the NBC for grouping cities/regencies based on the 2022 HDI indicators with an accuracy rate of 72.92%. Meanwhile, the NBC analysis only provides an accuracy of 64.58%. Three discriminant functions have been obtained to group cities/regencies on the island of Java based on the largest discriminant score where life expectancy makes the largest contribution in distinguishing each group.

Conclusion: As a result, in this case LDA is a better classification method than the NBC. It is also of important to note medium class regions for further actions from stakeholders.
Hypercholesterolemia Familial: Early Cardiovascular Complications, Treatment Challenges, and the Fatal Consequences of Delayed Diagnosis: an in-Depth Case Study
Authors: Boutgourine Mina , Rouam Hafssa , Jamili Mohammed El , Hattaoui Mustapha El
Published: February 2024

Familial Hypercholesterolemia (FH) is among the most common genetic disorders, present from birth. The transmission is mainly autosomal dominant. It is characterized by a exclusive increase in low-density lipoproteins (LDL). It is associated with a high risk of premature cardiovascular complications. The diagnosis of FH is generally based on the clinical presentation or genetic tests. The commonly used criteria are those of the Dutch Lipid Clinic Network. FH is a hereditary condition still largely underdiagnosed and undertreated. The prognosis of the disease is related to atheromatous cardiovascular complications, which, in the absence of treatment, lead to the patient's death in the first three decades, often due to myocardial infarction or sudden death. The management of familial hypercholesterolemia systematically involves two categories of measures: so-called hygienic-dietary measures associated with the treatment of other risk factors when they exist, and drug treatments. Familial hypercholesterolemia is still poorly detected. It is necessary to develop systematic approaches to identify patients with FH, conduct cascade screening of their relatives, and increase awareness and control of FH.
AgriTech Revolution: Next-Generation Supply Chain in America's Agriculture
Authors: Adesiyan Joseph Seun , Raffington Andrew Everton
Published: February 2024

With the advent of the 21st century, a novel era of technological advancement has profoundly impacted several sectors, with the inclusion agriculture. This paper examines the transformative task of evolving technologies in reorchestrating the agricultural supply chain during the revolutionary wave of AgriTech in American agriculture. As part of this research, we will analyze how cutting-edge technologies, such as the Internet of Things (IoT), Artificial Intelligence (AI), robotics, bigdata, and blockchain, are being integrated, and examine how these technologies have an impact on agricultural practices, supply chain efficiency, and sustainability in general. With a comprehensive literature review and case study analysis, the study explores AgriTech in the United States and its trajectory towards a more data-driven, automated, and interconnected agriculture industry. The paper determines how these innovations lead to increased crop yields, improved resource management, and extra transparent and robust supply chains. Furthermore, the research addresses the challenges, including the digital divide, investment barriers, and skill gaps, which could impede the widespread adoption of these technologies. Furthermore, our study reignites the opportunities presented by AgriTech, such as reduced environmental footprint, improved food safety, and the potential to meet the increasing global food demand sustainably. The future endeavor speculates on the evolving landscape of AgriTech, positing a scenario where advanced technologies not only dictate farming practices but also reshape the entire food supply chain, from farm to fork. Hence, the research presents a critical analysis of the next-generation supply chain in American agriculture, driven by AgriTech innovations. The result aims to provide valuable insights for stakeholders such as farmers, agribusinesses, technology providers, policymakers, and consumers, offering a comprehensive understanding of the dynamic interplay between technology and agriculture in the modern era.
Identifying Sustainable Biomedical Solid Waste Management Practices in the Context of Limited Resources in Selected Healthcare Facilities in Douala Cameroon
Authors: Peter Nkwenti , Marie Etame Loe Gisele , Nga Nnanga
Published: February 2024

Aims: To Identify sustainable Biomedical solid waste management practices in the context of limited resources in selected HCFs in Douala, Cameroon.

Study Design:  A cross-sectional survey with quantitative and qualitative study design was adopted for data collection from workers in the HCFs and also identifying the process of waste management.

Place and Duration of Study: This study was carried out in the some selected HCFs in the Douala region of Cameroon between January 2023 to June 2023.

Methodology: Study respondents were working in different sections of the HCFs and comprised of the following categories: doctors, laboratory scientists, cleaners, nurses and administrative/clerical workers. Field visitations and interactions with HCFs officials took place during the random sampling technique which was used in determining the sample size of 200 workers, Out of the sample size of 200 who were given questionnaires in order to provide data for the study, 150 valid mail questionnaires were retrieved and used for analysis. Every questionnaire was verified by validity. There’s also questions related funds, facilities availability, training and personal protective equipment. All of the data were coded and analyzed. The results were calculated based on sums and percentages of variables with SPSS vers.26 software and chi-square analysis with the level significance of p-value less than 0.05 was analyze

Results: This finding could also indicate that imbibing sustainable biomedical wastes management practices increases with higher experience in the hospital. Furthermore, communal bin disposal of biomedical wastes was the only statistically significant category under disposal method, indicating that waste disposal may be lacking in terms of sustainable practices. [30] also identified biomedical wastes disposal in open dumps among health workers in Saudi Arabia, attributable to poor sustainable waste training and lack of regulatory frameworks. I PCA results indicate that there are two dimensions of prevalent biomedical wastes in the hospital studied, as explicated by the two components retained

Conclusion: The limited resources and government policies and local councils influences sustainable waste management practices and this paper aimed at identifying some of the solutions towards improving Sustainable waste management policies. The practice of biomedical waste management in the study area was low. Level of education, taking training on biomedical waste management, availability of color-coded three bins, and attitude of health care workers were significantly associated with biomedical waste management practices. Hence, in-service training is recommended to improve biomedical waste management practices.
A Study of ZSM-5 Molecular Sieve Shaping for an Innovative Cyclohexene Hydration Process
Authors: Wang Baohe , Jin Dianyi , Zhang Zhaobang , Ai Zihan , Zhu Jing
Published: February 2024

The development of the zeolite molecular sieves (ZSM-5) molding technique is essential for the cyclohexene hydration reaction distillation process in both industrial and research settings. The reactive distillation process can solve many of the drawbacks associated with the existing technique of manufacturing cyclohexanol via cyclohexene hydration, such as high catalyst digestibility, low conversion rate, and operational challenges. This study developed a series of molded ZSM-5 catalysts with various binder types and contents were constructed. The suggested pseudo-boehmite and hydroxypropyl methylcellulose were chosen as binders for extrusion molding of ZSM-5. The effects of binders on the strength reliability were investigated by strength tests and statistical analysis of the Weibull function. The effects of binders on the physical structure, acidity, and catalytic performance of ZSM-5 were investigated by X-ray diffraction, scanning electron microscopy, physical adsorption of N2, and desorption of NH3. The findings demonstrate that the addition of binder has no effect on ZSM-5's crystal structure. The experiment's results showed that the molded catalyst could be used for the hydration process with over 95% selectivity and a yield of 10.45% cyclohexanol. Copyright © 2024 by Authors, Published by BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Preliminary results on the Immobilisation of Radionuclides from Waters with Specific Adsorbers Based on Phosphate Salts
Authors: Valentini Ganzerli Maria Teresa , Maggi Luigino , Crespi Caramella Vera , Berzero Antonella
Published: November 2004

The present paper is focused on the ability of aluminium phosphate (ALPC), magnesium ammonium phosphate (MGPC), magnesium hydrogen phosphate (MGHPC), and calcium hydrogenphosphate(CAHPC), adsorbed onto charcoal, to immobilise actinides by adsorption from natural waters. The objective of this process is to evaluate the environmental pollution due to the actinides. Europium, thorium, protactinium, neptunyl, and uranyl ions were chosen to simulate actinides in the +3, +4, +5 and +6 oxidation state. The adsorbers were tested using natural waters samples. The adsorption trends and capacities were analysed. ALPC and MGPC exhibited a similar behaviour and adsorbed demonstrating that the +5, +4 and +3 actinide ions can be easily immobilised from natural waters and may be successfully used at pH 7—8. MGHPC may be used at a higher pH, whereas CAHPC is effective in the whole pH range. In all cases, thorium, protactinium and europium were strongly
Determination of Metal Components in Marine Sediments Using Energy‐Dispersive X‐Ray Fluorescence (ED‐XRF) Spectrometry
Authors: Tung Joanne Wai Ting
Published: November 2004

A rapid energy‐dispersive X‐ray fluorescence (ED‐XRF) spectrometric method for the analysis of metal components of marine sediments has been presented. Calibrations were made using synthetic matrix. The agreement of the results for sediment standard reference materials with reference values is satisfactory. Major advantages of the nondestructive ED‐XRF technique over conventional chemical digestion methods include the applicability to analyzing the major oxide components, as well as to trace metals, and the avoidance of hazardous chemicals. The method has been applied to the routine analysis of Hong Kong marine sediment.
Separation of B6 Vitamers with Micellar Liquid Chromatography Using UV and Electrochemical Detection
Authors: Hadjmohammadi Mohammad Reza , Momenbeik Fariborz , Hoseinalizade Khorasani Jafar
Published: November 2004

Separation of six vitamers of vitamin B6 was performed by RP‐HPLC using micellar mobile phase, UV and electrochemical detection. Effect of temperature, type and amount of organic modifier in mobile phase on efficiency and asymmetry factor showed that, the appropriate conditions were temperature of 35 °C and 3.0‐5.0 % (v/v) 1‐butanol in mobile phase. Variations of selectivity factor versus 1‐butanol concentration, pH of mobile phase, and SDS concentration was investigated and the following optimized conditions were selected for the separation: 3.0 % (v/v) 1‐butanol, pH=5.5 and 65 mM SDS in mobile phase. Electrochemical behavior of vitamers in optimized mobile phase was investigated using cyclic voltammetry, and potential of +1.2 V versus Ag/AgCl(Sat.) was chose as working potential. Finally, separation of B6 vitamers using UV detection at 254 nm and electrochemical detection at +1.2 V was compared.
Risk and protective factors for Parkinson's disease: A study in Swedish twins
Authors: Wirdefeldt Karin , Gatz Margaret , Pawitan Yudi , Pedersen Nancy L.
Published: November 2004

Many studies have shown a protective effect of cigarette smoking on Parkinson's disease. However, criticism has been raised concerning confounding by genetic factors. We investigated the associations between Parkinson's disease and smoking, alcohol, coffee, area of living, and education in a co‐twin control study. Because twins are matched for genetic and familial environmental factors, this design controls for confounding by these factors. We also examined control subjects unrelated to cases. Exposure information was taken from questionnaires answered in the 1960s and 1970s. Parkinson's disease cases were identified through the Swedish Inpatient Discharge Register (IDR) and the Cause of Death Register. In the unrelated control subject comparison, 476 Parkinson's disease cases and 2,380 control subjects were included. In the co‐twin control comparison, 415 same‐sex twin pairs were included. There was an inverse association between smoking and Parkinson's disease using unrelated control subjects and co‐twin control cases. There was no association between Parkinson's disease and alcohol, coffee, or area of living. High educational level was associated with Parkinson's disease in the unrelated control subject comparison but not in the co‐twin control comparison. We confirm the protective effect of smoking on Parkinson's disease and establish that the association is only partially explained by genetic and familial environmental factors. Ann Neurol 2004
Untreue Enzyme in der Biokatalyse: mit alten Enzymen zu neuen Bindungen und Synthesewegen
Authors: Bornscheuer Uwe T. , Kazlauskas Romas J.
Published: November 2004

Mit der Entdeckung hochstereoselektiver Enzyme mit breiter Substratspezifität hat sich die Biokatalyse in den letzten Jahrzehnten rasant entwickelt. Ein neues Forschungsgebiet beschäftigt sich mit Enzymen, die eine breite Reaktionsspezifität bei der Katalyse alternativer Reaktionen aufweisen. Oft unterschätzt, spielt diese katalytische Promiskuität (catalytic promiscuity) eine natürliche Rolle in der Evolution und in manchen Fällen auch in der Biosynthese von Sekundärmetaboliten. In diesem Kurzaufsatz werden Beispiele für katalytische Promiskuität mit aktuellen und möglichen Anwendungen in der Synthese vorgestellt. Kombiniert mit Protein‐Engineering könnten dank dieser Eigenschaft die Verwendungsmöglichkeiten von Enzymen in der organischen Synthese deutlich erweitert werden.