bluuebunny/crossref_metadata_2025 huggingface dataset:
SAĞLIK HİZMETLERİNDE HASTA GÜVENLİĞİ VE YAPAY ZEKA: BİBLİYOMETRİK BİR ANALİZ
Authors: Şahin Dilek
Published: December 2024

Bu çalışmanın amacı, sağlık hizmetlerinde hasta güvenliği ile ilgili yapay zeka içerikli yayınların bibliyometrik analizini gerçekleştirmektir. Web of Science’da, 24/09/2024 tarihinde 1991-2024 yılları arasındaki hasta güvenliğinde yapay zeka konularını kapsayan İngilizce olarak yayınlanmış sağlık hizmetlerine yönelik araştırma ve derleme makaleler taranmıştır. Analizler açık kaynak kodlu R tabanlı bibliometrix aracı ve Biblioshiny web kullanıcı ara yüzü kullanılarak gerçekleştirilmiştir. Taramalar sonucu, hasta güvenliği ve yapay zeka konularına ilişkin 1273 yayına ulaşılmıştır. Araştırmaya dahil edilen makalelere 61 ülkeden 2267 kurumun dahil olduğu, bu yayınların 692 dergide yayınlandığı ve 7908 yazar tarafından yazıldığı saptanmıştır. Yayınların 2019 yılından sonra hızlı bir ivme kazandığı ve tüm yayınların %85,46'sının son beş yıldaki çalışmalardan oluştuğu belirlenmiştir. Bu konuda en fazla yayına sahip olan ülke Amerika Birleşik Devletleri ve en çok yayın yapılan dergi Cureus Journal of Medical Science’dır. Konuya ilişkin en fazla yayını olan yazar Bates D. W.’dir. Anahtar kelimeler ile eş-oluşum ağ analizi yapılmış ve 6 küme ortaya çıkmıştır. Hasta güvenliği ve yapay zeka konusunda yönergeler, etkililik, bilgisayar-destekli tespit konuları trend konular olarak ortaya çıkmıştır. Araştırma kapsamında gelecekteki hasta güvenliğinde yapay zeka araştırmalarını ilerletmek için özellikle uluslararası iş birliğine odaklanılması ve hasta güvenliğinde yapay zekanın kullanımına ilişkin sınıflandırmaların yapılması önerilmektedir.
A Bibliometric Analysis of Publications on Political Advertising in Web of Science and Scopus Databases
Authors: Uçak Aziz
Published: December 2024

In this article, a bibliometric analysis is conducted by means of VOSviewer software to put forward the bibliometric view of academic works on political advertising in Web of Science and Scopus databases. In this direction, general data regarding the publications in the databases as well as citation, co-authorship, and bibliographic coupling maps of the publications are presented. In this way, the study aims to see the place of political advertising studies in other academic works. The data related to the publications were collected from Web of Science and Scopus databases on 31.07.2024. While the first political advertising publication indexed in Scopus was published in 1972; the first publication on the topic was published in Web of Science in 1976. Hence, whereas the analyses in relation to Scopus database cover the dates between 1972 and 31.07.2024; the analyses related to Web of Science database cover the dates between 1976 and 31.07.2024. There are 868 detected publications in total on the topic in Scopus, whereas there are 739 in Web of Science between those dates. Analyzes indicate that the data in both databases considerably put forward consistent results with each other.
La represión económica en la provincia de León durante la Guerra Civil y la posguerra: las incautaciones de bienes
Authors: Rodríguez Guerra Ana Cristina
Published: December 2024

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EVALUATION OF ASPERGILLUS NIGER CONTAMINATION AND OCCURRENCE OF CITRININ IN RED CHILLI (CAPSICUM ANNUUM) SAMPLES
Authors: Mishra Arpita , Menon Sangeetha , Emmanuel E.S Challaraj , Ravichandran Kushbu
Published: December 2024

Numerous Ascomycete fungi produce toxic, low-molecular-weight secondary metabolites known as mycotoxins. Mycotoxin contamination poses a global challenge to food safety, and growing regulatory expectations regarding the presence of mycotoxins in various products have spurred increased research into detecting these toxins in food and animal feed. Mycotoxin contamination has been reported in many significant spices, including chillies. However, most research has focused on aflatoxins as primary contaminants, highlighting the need to investigate other lesser-studied mycotoxins, such as citrinin and patulin. Consequently, the current study aimed to screen for fungal contamination in locally available red chilli varieties and detect the presence of mycotoxins. Random samples of red chilli were collected to isolate and identify the fungi responsible for producing mycotoxins. High-performance liquid chromatography (HPLC) techniques and Fourier transform infrared (FTIR) spectroscopy were employed to analyze the extracted mycotoxins qualitatively. Morphological and molecular characterization through 18S rRNA sequencing of the isolated samples confirmed the presence of Aspergillus niger in red chilli. HPLC and FTIR analyses of the red chilli samples confirmed the occurrence of citrinin. Very few studies have reported the production of Citrinin by A. niger in red chilli. Further research is necessary to conduct quantitative analyses and assess the effects of citrinin on human health.
Effect of salinity stress on antioxidant activity and secondary metabolites of Piper betle
Authors: Sahu Abhaya Kumar , Priyadarshini Preeti , Dash Bishakha , Behera Beda Saurav , Gochhi Sunil Kumar , Pradhan Dipransu , Kumari Punam
Published: December 2024

Salt stress is the most devastating abiotic stress that drastically limits the productivity and quality of crops. This study assessed the impact of NaCl concentrations (100, 200, and 400 mM) on betel vine's antioxidant activities and secondary metabolites (Piper betle L.). Results of the study suggest that the activity of antioxidative enzymes was enhanced at 100 and 200 mM NaCl levels but reduced at 400 mM NaCl. Further, the GC-MS analysis revealed the increased production of secondary metabolites such as alkane, ester, fatty acid, phenolic, and terpene compounds during salt stress. These findings would be helpful for further investigations that could lead to enhanced production of secondary metabolites in betel vine for industrial and medicinal benefits.
Introgressing photoperiod/thermo-sensitive genic male sterile gene into Basmati 370 rice
Authors: Nyankemba Beatrice Nyarangi , Arunga Edith Esther , Nthakanio Paul Njiruh
Published: December 2024

The emasculation of male gametes in pollen-recipient parents among self-pollinated crops (rice) is key to producing quality hybrid rice seeds. One of the emasculation tools in rice breeding is the photoperiod-thermo sensitive genic male sterility (P/TGMS) method, which ultimately requires long daylight length and high-temperature growth conditions to induce male gametes sterility. Using the P/TGMS method to produce hybrid Basmati rice seeds has been slow because no commercial line has been developed. Crossing the Basmati rice line with a non-aromatic rice line produces F1 with non-basmati quality traits. This study aimed to introgress the p/tgms12-1 gene into Basmati 370 by treating P/TGMS lines (IR-7327-2376-157S and IR-75589-31-27833S) with daytime temperatures (>33ºC) under a polythene greenhouse to emasculate pollen and cross-pollinating them with Basmati 370. Marker-assisted backcrossing was used to develop the BC1F2 Basmati breeding lines evaluated for pollen sterility and agro-morphological traits. Pollen sterility was tested by staining with 1% iodine potassium-iodide solution (I2KI), in which fertile and sterile pollen grains were stained with blue-black and yellow-pink dyes, respectively. The acquisition of near-complete pollen sterility among female parents is a manifestation of the greenhouse temperatures effectively emasculating pollen in P/TGMS parents and BC1F2. Analysis of variance on agro-morphological data showed significantly better agro-morphological traits in BC1F2 than the parents and significantly higher pollen sterility in P/TGMS lines than Basmati 370 (P≤0.05). The presence of the fgr gene in BC1F2 lines was confirmed using SSR markers, and the hybrids had both homozygous aromatic and heterozygous non-aromatic traits, the successful development of BC1F2 with p/tgms12-1 and fgr genes. The results obtained from this study are a major milestone towards improving Basmati rice yields in Kenya using hybrid seeds.
Sağlık Yönetimi Öğrencilerinin Yeşil Yönetim ve Sürdürülebilirlik Algısının İncelemesi
Authors: Akgün Feyza
Published: December 2024

Topluma çevre sorunlarına duyarlı bireyler kazandırmanın yolu bireylerde yeşil yönetim ve sürdürülebilirlik kavramlarının algılanması ve geliştirmesiyle mümkündür. Sağlık sektörü gibi köklü bir hizmet sektörünün yeşile dönmede payı oldukça büyüktür, bu bağlamda, geleceğin sağlık yöneticilerinin yeşil yönetim ve sürdürülebilirlik adına bilgi birikimine sahip olmaları ve gelecekte mesleki hayatlarında bu bilgi birikimini iş hayatında uygulamaları gerekmektedir. Bu çalışmada, yeşil yönetim ve sürdürülebilirlik kavramları araştırılmış, ayrıca öğrencilerle yarı yapılandırılmış görüşmeler yapılarak açık uçlu sorular sorulmuş bu soruların cevapları ana başlıklar altında birleştirilerek yorumlanmış, metaforik incelemeler yapılarak ve son olarak öğrencilerden görüşmelere gelirken ilgili çalışmanın öğrencilerde uyandırdığı fikirlere yönelik fotoğraflamaya dayalı görseller (fotoğraflar) getirilmesi istenerek bu fotoğraflar kapsamındaki öykülemeler (metinler) oluşturulmuştur. Öğrencilerin sürdürülebilirlik konusunda değindikleri önemli tema olan geri dönüşüm faaliyetleriyle ilgili verdiği bilgiler incelenmiş ve bu konudaki bilgi düzeylerinin yeterli olduğu kanısına varılmıştır. Ayrıca, yeşil yönetim denildiğinde hastanelerde yapılan çalışmalarla ilgili bilgi düzeyi yeterli bulunup bulgularda açıklanmıştır.
Review the Importance of Breastfeeding from the Perspective of the Holy Quran and Medical Literature
Authors: Yavari Mohammad Reza , Salmani Mohammad Javad , Barzegar Kazem , Salmani Nodoushan Mohammad Hossein
Published: December 2024

Background: Mother's breast milk is the sole and best food for a neonate. It is one of the blessings of Almighty God that is physiologically given to the child through the mother’s breast. Breastfeeding is one of the issues receiving special attention in the Holy Quran. Nowadays, this issue has been explored and investigated in scientific and medical literature. In the present review, the importance of breastfeeding was examined from the reported medical scientific studies and articles and compared with the verses of the Holy Quran and authentic Islamic traditions.
Methods: This study was a review developed by PubMed, Web of Science, and Google Scholar using predetermined keywords. Authentic valid narrations related to breastfeeding in Arabic and articles published in English during 2014-2024 on its importance in neonatal health were selected by the present researchers. After applying inclusion criteria, the papers related to this topic were screened by experts for suitability.
Results: This review included one verse of the Holy Quran, 3 valid authentic Islamic traditions, and 6 scientific medical literature highlighting the importance of mothers’ breastfeeding. Thematic analysis indicated the health and safety of mothers during breastfeeding. Breastfeeding duration and breastfeeding time are important points in the Holy Quran and traditions emphasized by researchers.
Conclusion: The present study revealed that the results of scientific medical literature, like the Holy Quran, emphasized the importance of breastfeeding. There are special instructions for breastfeeding in the Holy Quran. Today, the guidelines of the Quran in this field of study are emphasized in scientific research articles.
The Impact of Bullying on Adolescent : A Systematic Review
Authors: Paramita Sintia , Palipung Rizky Yuniarti , Ni'matuzahroh
Published: December 2024

Bullying is an act that can hurt others both verbally and non-verbally which is carried out continuously and over a long period of time. Bullying behavior can cause the victim to be in a constant state of intimidation. The purpose of this systematic review is to determine the impacts of bullying behavior on adolescents. There are twelve journals that provide information related to the dangers and what are the impacts of bullying behavior on adolescents. The literature search was conducted using one database, Scopus. Only studies that were published in English and examined bullying and the impact of bullying were included in this systematic review. The results of this systematic review revealed that bullying behavior has many negative impacts on both perpetrators and victims, including disrupting mental health and physical health, lowering academic achievement, and can even lead to suicidal behavior.
Cooperative identity: a systematic literature review
Authors: Barden Júlia Elisabete , Forgiarini Deivid Ilecki , Sindelar Fernanda Cristina Wiebusch , Cyrne Carlos Cândido da Silva , Garcia Alexandre de Souza
Published: December 2024

Cooperatives driven by the Cooperative Identity have a scope of action that goes beyond their economic purposes. This article aims to understand how the Cooperative Identity has been discussed between the years 2019 to 2023. A systematic literature review was conducted using the Methodi Ordinatio approach on databases, and the content was analyzed using Mendeley®, VOSviewer®, and NVivo® software. The results indicate a prevalence of discussions on the 5th principle (Education, Training, and Information) and little discussion on the other six principles. Among the principles not discussed are those that impact management and, in turn, can strengthen the Cooperative Identity. In general, cooperatives are mainly treated as mere subjects of study.
Received: 23 October 2023 Accepted: 11 October 2024
Análisis de la política pública para la gestión de la Economía Social en el Estado de Tlaxcala, México
Authors: Medina Conde Analaura , Flores Ilhuicatzi Uziel
Published: December 2024

La Economía Social es un importante instrumento para el crecimiento económico y vertebración territorial, por ello, el objetivo es analizar la política pública implementada para la gestión de la Economía Social en el Estado de Tlaxcala. La metodología consiste en un estudio de dogmática jurídica y un análisis estádistico descriptivo. En los resultados, se observa un decremento neto del 76,47% del monto de apoyos en el periodo 2013-2019, en el año 2019 solo 12 municipios recibieron apoyo representando el 19,67% y una disminución del 81,97% respecto del año 2018, lo que demuestra falta de voluntad política de motivar la Economía Social en el estado.
Recibido: 11 enero 2024Aceptado: 09 noviembre 2024
La buena persona cooperativa educada y comprometida como estándar fiduciario de conducta aplicable a los sujetos particulares del derecho cooperativo: una propuesta doctrinaria para Latinoamérica
Authors: Colón Morales Rubén
Published: December 2024

El Derecho cooperativo Latinoamericano carece de una normativa jurídica especializada sobre los deberes de fiducia de los sujetos especiales del Derecho cooperativo, diseñada específicamente en función de los preceptos filosóficos y valores del cooperativismo. En algunas jurisdicciones incluso subsiste la práctica de recurrir al uso de arquetipos conductuales desarrollados en otros contextos del Derecho Empresarial, cuya aplicación dentro del Derecho cooperativo resulta contraria a su esencia filosófica. Sostenemos que el desarrollo y consolidación del Derecho cooperativo precisaría de la elaboración de estándares conductuales jurídicos específicamente diseñados para regir a los sujetos particulares del Derecho cooperativo. A base de la amplia literatura filosófica examinada proponemos la incorporación dentro de los cuerpos normativos del Derecho cooperativo Latinoamericano un estándar fiduciario especialmente construido para regir la conducta de tales, a saber: el arquetipo de las buenas personas cooperativas educadas y comprometidas.
Recibido: 21 mayo 2024 Aceptado: 05 noviembre 2024
La fiscalidad adecuada como herramienta impulsora de la creación de las sociedades cooperativas en el sector de la pesca y la acuicultura
Authors: Aranburu Edriga
Published: December 2024

El objetivo de este trabajo es analizar la fiscalidad que se les aplica a las sociedades cooperativas que operan en el sector de la pesca y acuicultura para que así se pueda optar por la creación de estas sin tener que elegir el modelo usual de las sociedades mercantiles que se rigen por la Ley Real Decreto Legislativo 1/2010, de 2 de julio, por el que se aprueba el texto refundido de la Ley de Sociedades de Capital. De esta manera se pretende poner en valor a las sociedades cooperativas del mar como modelo a seguir en el mundo globalizado en el que vivimos.
Recibido: 27 mayo 2024Aceptado: 23 octubre 2024
AI in supply chains: freedom from slavery revisited
Authors: Laukyte Migle , Arismendy Mengual Lorena María
Published: December 2024

This paper addresses the link between Artificial Intelligence (AI) and the human and fundamental right to freedom from slavery: in particular, we focus on the modern slavery in global supply chains and the possibility to use AI to identify it. We analyze the slavery and its modern version, situate the AI within the human rights debate and argue that we should not only focus on how AI can violate and infringe the human rights, but also explore how AI could be useful in identifying violations and helping to combat them. We emphasize the need for inclusive datasets and stakeholder oversight and argue in support of AI to enhance transparency of international supply chains while cautioning against biases. We conclude by outlining the importance of responsible AI deployment and making a case for more regulatory efforts to protect the fundamental human right to freedom from slavery in supply chain operations.
Received: 27 May 2024Accepted: 12 September 2024
The human right to participate and its connection to artificial intelligence
Authors: Montero Caro María Dolores
Published: December 2024

This article analyses the right to participate in democracy as a human right and its link to the development and implementation of artificial intelligence. First, it explores the fundamental aspect of the right to participate as a human right in the democratic framework, reflecting on its importance and its basic function of generating open spaces for the debate and presentation of other rights, highlighting that political participation generates a pull effect on other rights as citizens are in a favourable position for the defence and recognition of their rights. Next, emphasis is placed on the role of emerging technologies in facilitating and enhancing democratic engagement, bearing in mind that technological development has a direct influence on all aspects of people’s lives, so that democracy in general, and each society’s methods of organisation in particular, are also affected. Finally, a significant part of the discussion revolves around the future perspective of artificial intelligence and its potential impact on democracy, exploring both favourable developments and potential challenges. Artificial intelligence will undoubtedly continue to conquer more spheres of human endeavour, so it is worth reflecting on the importance of adapting this new technology to the future of democracies, while respecting its essential elements and guaranteeing citizens’ fundamental rights. Finally, the article concludes by summarising the main ideas and implications, underlining the critical importance of safeguarding democratic principles in the midst of technological advances.
Received: 30 May 2024 Accepted: 02 December 2024
Towards a better protection of human rights through the use of AI and related technologies in budgeting and auditing of public expenditure
Authors: Grau Ruiz María Amparo
Published: December 2024

The full potential of many human rights cannot be reached due to the economic costs in their development. The use of artificial intelligence and related technologies in budgetary and audit processes could help in a better allocation of scarce public resources and deliver savings due to better targeting in programming and execution, avoiding irregularities and corruption. When public and corporate organizations automate processes, monitoring should ensure their compliance with regulation or voluntary commitments affecting environmental, social, and governance criteria. Many funds are granted to support digitalization processes if safeguards related to human rights are respected. The provision of goods and services like health and education is often subject to additional technological requirements. In both cases, an efficient supervision is crucial for fairness, in terms of accessibility and the effective protection of human rights.
Received: 08 September 2024 Accepted: 10 December 2024
Impacto de la inteligencia artificial en los derechos de los interesados: una perspectiva práctica
Authors: González Tapia María Luisa
Published: December 2024

Los denominados derechos del interesado, que aparecen regulados en el Capítulo III del Reglamento (UE) 2016/679, constituyen una de las principales herramientas puestas a disposición de los individuos para conseguir el control efectivo sobre sus datos personales. Entre dichos derechos figuran los de acceso, rectificación, supresión, oposición, portabilidad y limitación del tratamiento, además del poco ejercitado hasta la fecha derecho a no ser objeto de decisiones automatizadas. Como norma general, estos derechos son directamente exigibles frente al responsable del tratamiento, que debe dar una respuesta formal dentro un plazo definido, incluso en aquellos supuestos en que corresponda la denegación de la solicitud. Este artículo analiza los cambios que la sucesiva implantación de sistemas de inteligencia artificial puede provocar en las peticiones de los afectados y los problemas prácticos a los que, previsiblemente, se enfrentarán los responsables del tratamiento que deban darles respuesta. En particular, resalta la importancia de realizar una adecuada interpretación y aplicación del artículo 22 del citado Reglamento (UE) 2016/679, relativo a decisiones automatizadas.
Recibido: 30 mayo 2024 Aceptado: 25 octubre 2024
Balcerzak, Michal and Julia Kapelańska-Pręgowska, eds. 2024. Artificial Intelligence and International Human Rights Law. Developing Standards for a Changing World
Authors: Artíñano Ortiz Itziar
Published: December 2024

This work analyzes the intersections between artificial intelligence (AI) and human rights from an international perspective. It analyzes the regulatory efforts of essential entities such as the United Nations, the Council of Europe, and the European Union. Recent initiatives that aim to establish ethical and legal standards to address the risks associated with AI are highlighted. Mass surveillance, algorithmic bias, and privacy violations stand out among these aspects. The book takes a unique approach, integrating a normative perspective with analyses of specific cases to examine the impact of artificial intelligence in key areas such as justice, health, labor rights, and privacy. It delves into challenges such as video manipulation, facial recognition regulations, and ethical conflicts in applying autonomous technologies in international settings. The book underscores the necessity of a flexible legal framework that accommodates technological advances while upholding fundamental rights. It also underscores the need to strengthen the responsibility of states and private entities to protect these rights. This volume is a fundamental reference point in the creation of international norms that ensure artificial intelligence respects human rights and proactively participates in their promotion in a globalized and constantly evolving world. Its insights are invaluable in the field of AI ethics and human rights.
Hıdırellez As An Experience Of Women's Self-Presentation In A Mediterranean Village
Authors: Durna Nehir
Published: December 2024

Ritüeller, toplumsal belleğin aktarılarak devamlılığının sağlandığı ve bugünün yeniden üretildiği, tekrara dayalı en temel pratiktir. Hıdırellez, durağan kış mevsiminin sona ererek doğanın canlandığı ve yeni bir yılın başlangıcını temsil eden bahar mevsiminin karşılandığı mevsimsel geçiş ritüelidir. Hıdırellez kutlamalarını Antalya-Elmalı Tekke köyünde yaşayan kadınların anlatıları üzerinden değerlendiren bu makale, gözlem ve derinlemesine görüşmelerden oluşan saha verilerine dayanmaktadır. 
Tekke Köyü’nde Hıdırellez’e dair bilginin kuşaklararası aktarımında, ritüel ve uygulamaların devam ettirilmesinde kadınlar da önemli rol oynamaktadır. Aynı zamanda kutlama ve ritüeller içinde köy kadınları için sıkı örüntülere sahip gündelik hayat ve ev sınırları dışına çıkma olanakları da barındırmaktadır. Makalede, bu olanakların sınırları ve geçmişten bugüne Hıdırellez’in Tekke Köyü sakini kadınlar tarafından hangi ritüel, inanış ve uygulamalarla kutlandığı ele alınmaktadır.
Makalenin temel sorunsalı Hıdırellez ritüelinin köy kadınlarına köy hayatının yeknesak rutinini bozacak ve kendi varlığını özgürce deneyimleyebileceği bir imkân alanı sunup sunmadığıdır. Hem geleneksel hem de dini bir veçhesi olan Hıdırellez ritüelinin kadınlar tarafından geçmişten günümüze nasıl deneyimlendiğine dair değişimi anlamak için farklı yaş aralıklarından kadınların tanıklığına başvurulmuştur. Farklı kuşaklardan kadınların Hıdırellez deneyimlerine dair farklar, bahse konu imkân alanının sınırlarını anlamamız açısından önemli ipuçları sunmuştur.
Serologic predictors of thyroid immune-related adverse events during immune checkpoint inhibitors therapy: a retrospective cohort study
Authors: Glibka Anastasia A. , Mazurina Natalia V. , Sarantseva Ksenia A. , Kharkevich Galina Y. , Volkonskii Mikhail V. , Elfimova Alina R. , Troshina Ekaterina A.
Published: December 2024

Rationale: Immune-related adverse events (irAEs) are a specific type of drug toxicity that can occur in cancer patients undergoing immunotherapy with immune checkpoint inhibitors (ICIs). Endocrine irAEs rank the 3rd after the skin and gastrointestinal ones. Clinical course of endocrine irAEs usually results in irreversible damage of the glands function. Prevailing thyroid disorders among endocrine irAEs, their reactivity compared to that of autoimmune thyroiditis, the risk of potential temporary or complete withdrawal of the immunotherapy would make it necessary to search for markers able to identify the most susceptible patient groups.
Aim: To evaluate an association between baseline laboratory parameters (hormonal, biochemical, and serological) in patients with malignant solid neoplasms before the first course of anti-tumor immunotherapy with ICIs in monotherapy and the subsequent development of thyroid irAEs.
Methods: In this retrospective cohort we analyzed medical files from 102 adult patients (50 (49%) men, median age 60 years) with confirmed solid malignant tumors who were treated in two specialized in-patient departments from January 2020 to February 2022. Their baseline blood samples for subsequent evaluation of thyroid function, carbohydrate and calcium metabolism, as well as to exclude adrenal insufficiency were taken before the initiation of the first course of specific immunotherapy with ICIs. Thereafter, the patients were monitored for any registered irAE for up to 34 months from the beginning of the antitumor immunotherapy with ICIs.
Results: Thyroid irAEs were registered in 13/102 (12.7%) patients. Only two markers were significantly associated with the development of thyroid disorders under immunotherapy with ICIs: baseline levels of anti-thyroperoxidase antibodies (TPOAb) ≥ 7.54 IU/mL (reference range (RR) 0–5.6) and anti-thyroglobulin antibodies (TgAb) ≥ 16.45 IU/mL (RR 0–115) (p 0.001). For TPOAb ≥ 7.54 IU/mL and TgAb ≥ 16.45 IU/mL, the areas under the ROC curve (AUC) were 0.828 [95% confidence interval (CI) 0.678–0.979] and 0.875 [95% CI 0.742–1.000], diagnostic sensitivity was 75% [95% CI 48–92] and 92% [95% CI 64–100], diagnostic specificity 92% [95% CI 85–96] and 84% [95% CI 77–86], prognostic values of the positive result 69% [95% CI 44–85] and 58% [95% CI 40–63], and prognostic values of the negative results 94% [95% CI 87–98] and 98% [95% CI 90–100], respectively.
Conclusion: Baseline levels of TPOAb and TgAb may serve as markers for the risk of thyroid irAEs in cancer patients with solid malignancies who are planned to receive anti-tumor immunotherapy with ICIs.
Effect of Motivational Interviewing on Medication Adherence in Patients with Bipolar Disorder: Systematic Review
Authors: Erkuş Şeyma , Babaoğlu Elçin
Published: December 2024

This systematic review was conducted to examine the effect of motivational interviewing method on compliance with medication treatment in individuals diagnosed with bipolar disorder. In this systematic review, the literature was searched in the databases of ''Cochrane, SpringerLink, Ovid, Science Direct, PubMed, ProQuest, Networked Digital Library of Theses and Dissertations (NDLTD), ULAKBIM, YÖKTEZ'', published in the last 5 years, in English language, using the keywords and combinations of ''motivational interviewing'', ''bipolar disorder'', ''adherence''. The titles and abstracts of the studies were reviewed and 6 studies, including 4 randomized controlled trials and 2 nonrandomized studies, that met the inclusion criteria were included in the systematic review. As a result of this systematic review, it was determined that the motivational interviewing method was effective in increasing medication compliance in patients diagnosed with bipolar disorder. In the studies, it was determined that motivational interviewing was applied alone, with medication reminder system or with an educational program. It was determined that motivational interviewing was applied twice a week or twice a month, between 20-60 minutes and between 3-6 sessions. Subjective and objective measurement tools assessing medication adherence and symptoms were used to evaluate the effect of motivational interviewing. It is recommended to increase randomized controlled experimental research examining the effect of motivational interviewing method on medication adherence in patients diagnosed with bipolar disorder and to use motivational interviewing techniques and skills by mental health professionals to increase patients' medication adherence.
Measuring Insight: A Comprehensive Look at Its Core Elements
Authors: Herdi Oğuzhan
Published: December 2024

The present article discusses the concept of insight in terms of the scales in the literature that measure or assess insight. A search of Google Scholar and PubMed using the terms 'insight scale', 'insight questionnaire', 'insight survey', 'insight checklist', 'insight inventory' and ‘insight + major psychiatric diagnostic categories’ identified 44 scales that assess 6 different insight themes: 1) psychological insight, 2) cognitive insight, 3) clinical insight, 4) therapeutic insight 5) social insight, 6) Buddhist insight. Psychological insight is the state of awareness and understanding of one's own feelings, thoughts, beliefs, behaviours, personality, traits and whatever belongs to the self and the self's relationship with the environment. Cognitive insight assesses how inclined and intentional the person is to reflect on the cognitions he/she holds and at the same time how firmly he/she holds to his/her beliefs and cognitions and how much he/she believes in their accuracy. Clinical insight assesses awareness of the illness, importance of the symptoms and awareness of the cost of the illness. Psychotherapeutic insight is a type of insight that can be related to the patient's therapeutic rapport, in which the patient's awareness of himself or herself and the relationship he or she establishes with his or her environment during the sessions. While social insight brings the construct of insight a social context, Buddhist insight is an introspection or insight which is the aim of Buddhist or mindfulness practice. In conclusion, insight has a complex and unique construct which causes confusion while identify it comprehensively. Although there is an abundance of work on insight in the literature, there is still some way to go to elucidate this concept.
Taubat dan Etika Kerja Islam Terhadap Kebahagiaan Pada Karyawan PT “X” Pekanbaru
Authors: Melisa Kurnia Asfitri  , Mawaddah Khairani  , Rahmadhini  , Tsurayya Syarif Zain  , Heni Yuvita  , Raras Risia Yogasnumurti  , Yoga Aji Nugraha
Published: December 2024

Setiap orang bekerja bertujuan untuk memperoleh kebahagiaan. Penelitian ini bertujuan untuk melihat hubungan antar taubat dan etika kerja islam terhadap kebahagiaan pada karyawan PT X Pekanbaru. Sampel dalam penelitian ini berjumlah 50 orang, teknik sampling yang digunakan adalah sampling jenuh. Alat ukur yang digunakan dalam pengambilan data adalah skala taubat yang disusun oleh peneliti, skala islamic work ethic scale yang dikembangkan oleh Abbas Ali yang telah diadaptasi oleh Jamil (2007) dan skala Oxford Happiness Questionnaire versi Indonesia yang telah diadaptasi oleh Rahmawati, Saragih dan Adeline (2016). Data dianalisis menggunakan analisis regresi linier berganda. Hasil analisis diperoleh nilai signifikansi sebesar 0,000 atau (p<0,05) yang menunjukkan hasil bahwa terdapat pengaruh yang signifikan antara taubat dan etika kerja islam terhadap kebahagiaan pada karyawan PT X Pekanbaru.
Mental Health Clinical Placement of Social Work Students in Greece: Learning Outcomes and Impact on Future Career in the Mental Health Field.
Authors: Martinaki Sophia , Dedotsi Sofia , Kontoangelos Konstantinos
Published: December 2024

Education in the mental health field allows the evaluation of factors that are shaped during the period of studies and thus affect students before their placement in a psychiatric setting. In particular, theoretical training, attitudes towards mentally ill people, the degree of preparedness, and the desire to pursue a future career in this field are important factors associated with mental health education. This study included 101 Greek undergraduate social work students who completed their clinical placement in the settings of the 1st Psychiatric Clinic of the National and Kapodistrian University of Athens (NKUA) – Eginitio Hospital. By filling out the P/MHCPS scale, these students evaluated their placement experience on the first and last day of placement. Significant differences were recorded at the second measurement time point in terms of attitudes, course effectiveness, preparedness for mental health field, and negative stereotypes. The students’ theoretical background, degrees of preparedness and self-confidence, more positive attitudes, career interest in mental health, and satisfaction with the working environment are factors that enrich the social work students’ learning journey and confirm the positive impact of their clinical placement in the mental health field.
An investigation into when and how to train medical students for the most effective learning of non-technical skills: A qualitative study
Authors: Riaz Salman , Naemi Roozbeh
Published: December 2024

This study aimed to explore the undergraduate level at which the non-technical skills (NTS) should be taught. The objectives were to explore teachers’ perceptions of the effectiveness of simulation for NTS training and designing NTS simulation sessions to achieve student competence. A qualitative design was adopted, by interviewing 30 teachers and then using 5 focused group discussions for data triangulation and confirmation of responses. Thematic analysis was conducted to analyse the data by focusing on the ideas, experiences, opinions and meanings presented by the participants. Most of the participants strongly believed in the benefits of teaching NTS from pre-clinical years. Teachers’ consensus was to train students in communication, situation awareness, teamwork and leadership skills from pre-clinical years. However decision-making and stress management were agreed to be trained from clinical years as they require clinical knowledge. The use of simulation was found to be most effective for training among other methods like didactic sessions, case-based discussions and video-assisted learning. Simulation sessions integrating technical and NTS, fewer learning outcomes and effective debriefing were considered advantageous for effective learning. Simulation-based education using a spiral curriculum approach, starting training from pre-clinical years and gradually increasing difficulty through intricate exercises in clinical years can be suggested to achieve the desired competence of NTS.
Algorithm of complexing sensor data for tasks of automatic control of rolling stock
Authors: Ivanov Vadim , Ohotnikov Andrey , Gradusov Aleksandr
Published: December 2024

the article analyzes the research and works on processing Sensor data processing and navigation for mobile objects, including those with automatic control. automatic control. It is pointed out the necessity of integration of solutions based on vision and neural networks, taking into account the state of the environment. on the basis of vision and neural networks, taking into account the state of the environment. environment. The description of the algorithm and methods for complexing data received from sensor sensors of the onboard vision system of the rolling stock. Within the framework of the algorithm work the trajectory data\ processing: confirmation (removal) of the observed objects, construction of their trajectories, estimation of velocities and coordinates, formation of the list of global objects. To calculate the object motion model, an extended Kalman filter is applied Kalman filter, Hungarian algorithm and calculation of the Mahalanobis distance. Detailed The stages of detection, tracking and identification of obstacle objects are described in detail, as well as determination of their parameters (class, coordinates and velocity). The Experimental indicators used in this study. Relevance relevance and shown practical applicability of the described approach for the tasks of automatic control of rolling stock in the conditions of a digital railroad
Políticas de preservação digital no Brasil: um panorama do estado da arte
Authors: Santos Gildenir Carolino , Grácio José Carlo Abbud
Published: December 2024

Introdução: A preservação digital é crucial para garantir a longevidade e acessibilidade de informações em formato digital no Brasil. Diversas instituições desenvolveram políticas para lidar com os desafios da obsolescência tecnológica e da vulnerabilidade dos dados. Objetivo: Este estudo analisa as políticas de preservação digital de diferentes instituições brasileiras, identificando características comuns, desafios e tendências. Metodologia: Foram analisadas 13 políticas de preservação digital de instituições como universidades, arquivos nacionais, bibliotecas e órgãos governamentais. A análise focou em características comuns e desafios presentes nas políticas. Resultados: As políticas analisadas demonstram uma abordagem multidisciplinar, priorizando a longevidade dos dados e o gerenciamento de riscos. Há um foco na padronização de processos, incluindo gestão de metadados e migração de formatos. A acessibilidade também é destacada. Contudo, persistem desafios como a falta de recursos, a necessidade de mudanças culturais nas instituições, a carência de legislação específica, e a constante adaptação às novas tecnologias. Tendências futuras incluem o desenvolvimento de plataformas colaborativas, a utilização de inteligência artificial e a capacitação profissional. Conclusão: O estudo revela um cenário de avanços e desafios na preservação digital brasileira. A implementação de políticas eficazes e a cooperação interinstitucional são cruciais para a salvaguarda da memória digital do país, considerando a contínua evolução tecnológica e a necessidade de garantir a acessibilidade a longo prazo.
Normal İşiten Tinnitus Hastalarında Yüksek Frekans Odyometrinin Rolü
Authors: Altay Cumhur , Uzun Tankut , Müderris Togay
Published: December 2024

Amaç
Konvansiyonel odyometri testi normal olan tinnitus hastalarında yüksek frekans odyometri testinin önemini ve olası patolojilerin erken saptanmasındaki rolünü araştırmak.
Gereç ve Yöntem
Ocak 2018-Ocak 2021 tarihleri arasında İzmir Bakırçay Üniversitesi Çiğli Eğitim ve Araştırma Hastanesi KBB Kliniğine belirgin işitme kaybı olmaksızın uğultu ve çınlama şikayeti ile başvuran ve konvansiyonel odyometri sonuçları normal olan 18-45 yaş arası 60 hasta ile herhangi bir şikayeti olmayan konvansiyonel odyometri sonuçları normal olan 54 hasta çalışmaya dahil edildi. Çalışmaya dahil edilen tüm hastalara yüksek frekanslı odyometri de yapıldı.
Bulgular
Çalışmaya katılan tüm hastaların sağ ve sol kulakları için saf ses ve yüksek frekans ortalamaları karşılaştırıldığında, her iki kulakta saf ses ve yüksek frekans değerleri arasında istatistiksel olarak anlamlı fark bulundu.
Tartışma
Mevcut bulgular ışığında saf ses odyometrinin koklea ve işitmeyi tam olarak değerlendiremediği görülmektedir. Yüksek frekanslı odyometride tespit edilen bulguların tinnituslu hastaların tedavisine yönelik yapılacak araştırmalar için ufuk açıcı olduğuna ve yüksek frekans odyometrinin işitme kaybının erken teşhisi için değerli veriler sağladığına inanıyoruz.
Sonuç
Kurulacak yeni odyometri ünitelerinde ve mevcut altyapının modernizasyonunda mutlaka yüksek frekanslı odyometri cihazlarının ekipmanlara dahil edilmesi gerektiğini düşünüyoruz.
Phyllodes Tumors of the Breast: Recurrence and the Importance of Clinical Follow-up
Authors: Kılıç Berkay , İlhan Burak
Published: December 2024

AIM: Phyllodes tumors, including benign and borderline types, have a substantial potential for recurrence. The objective of this study was to evaluate histologic features that can help predict recurrences, and to emphasize the importance of close follow-up in this regard.
MATERIAL AND METHOD: The demographic, clinicopathological characteristics, treatment approaches, and follow-up data of the 64 patients who were treated between 2006 and 2018 at the Istanbul University, Institute of Oncology with the diagnosis of phyllodes tumors were evaluated retrospectively by examining the patient files and pathology records.
RESULTS: The median age was 38.8±12.2. The median tumor size was 53.1 mm (range, 11 mm to 210 mm). The phyllodes tumors were classified as follows: benign (n= 36, 56.3%), borderline (n= 11, 17.2%), and malign (n= 17, 26.6%). High mitotic number, cellular pleomorphism, stromal overgrowth, tumoral heterogeneity, and tumor margin irregularity were found to be independent prognostic factors in the development of local recurrence. The common feature of tumor recurrence in the process of benign and borderline phyllodes tumors was tumor margin irregularity. The mean period of recurrence of phyllodes tumors was determined as 29.7 months (range, 10 to 64). In the study, 7 out of 10 recurrences were observed when excision was performed with an insufficient surgical margin of closer than 1 cm, and in three cases when a clear surgical margin was obtained far than 1 cm (p= 0.045).
CONCLUSION: Phyllodes tumors were classified as benign, borderline, and malignant. A negative surgical margin of ≥1cm plays a major role in the management of phyllodes tumors. The study may emphasize the importance of close follow-up, given that the recurrence period is short, especially if tumor margin irregularity is detected on definitive pathological examination, even if it is benign or borderline type.
Keywords: Phyllodes tumor, breast surgery, margin status
Complicated Intraabdominal Infections; Epidemiology of Microorganisms, Resistance Profiles ans Risk Factors Associated with Mortality
Authors: Üçer Sengül , Baykam Nurcan
Published: December 2024

Aim: The threat of antimicrobial resistance has been identified as one of the major challenges in the management of complicated intra-abdominal infections(cIAIs). In this study, we aimed to describe the clinical, microbiological and resistance profiles of complicated intra-abdominal infections and to assess the risk factors related to resistance and mortality.
Material and Method: Seventy-nine patients undergoing surgery or interventional drainage for cIAIs with a positive microbiological culture were documented.
Results: Among these patients 79,7% were affected by health care associated IAIs while remaining 20,3% cases were identified as cIAI in the community. In 79 cases, 143 microorganisms were isolated and the leading microorganism was E.coli (34.9%) followed by Enterococcus spp. (17.4%). Among Enterobacteriaceae (n:96), 53.6% of the strains had ESBL and 36.8% were Multi Drug Resistant (MDR) bacteria. The overall mortality rate was 22.8%. According to univariate analysis, the use of broad spectrum antibiotics between initial intervention and re-operation was a significant risk factor for presence of ESBL. By multivariate analysis of the data; isolation of MDR bacteria, Enterococcus spp as an etiologic agent and presence of chronic obstructive pulmonary disease were statistically significant indicators for mortality.
Discussion: These data indicate that local community and nosocomial resistance patterns should guide empiric antimicrobial therapy.
Conclusion: To have the efficient data for resistance patterns, culture of the materials should not be neglected in either hospital or community acquired IAIs.Due to the increase in the prevalence of ESBL positive and MDR bacteria, demonstration of the epidemiological data in populations and each hospital is crucially important for accurate selection of initial empirical antibiotherapy
Effectiveness of RFDT learning based on TPACK framework in improving the critical and creative thinking abilities of prospective biology teacher students
Authors: Siswati Bea Hana , Hariyadi Slamet
Published: December 2024

The emphasis on 21st-century skills, particularly critical and creative thinking, has driven educational advancements, including technology integration through frameworks like TPACK (Technological Pedagogical Content Knowledge). This study examines the effectiveness of RFDT (Reading, Finding, Discussing, and Talking) learning grounded in TPACK to enhance students' critical and creative thinking. Using a one-group pretest-posttest pre-experimental design, 30 biology education students in professional education courses were assessed through critical and creative thinking essay tests administered before and after TPACK-based RFDT learning. Findings reveal a significant improvement in both critical thinking scores (from 62.3 to 77.63) and creative thinking scores (from 61.8 to 80.76), with p < 0.05. These results highlight the potential of TPACK-based RFDT in developing essential thinking skills, promoting a dynamic and interactive learning environment. Future research with a larger sample and advanced experimental designs is recommended to validate these findings further.Abstrak. Penekanan pada keterampilan abad ke-21, terutama berpikir kritis dan kreatif, telah mendorong kemajuan pendidikan, termasuk integrasi teknologi melalui kerangka TPACK (Technological Pedagogical Content Knowledge). Studi ini meneliti efektivitas pembelajaran RFDT (Reading, Finding, Discussing, and Talking) berbasis TPACK dalam meningkatkan kemampuan berpikir kritis dan kreatif siswa. Dengan menggunakan desain pra-eksperimen pretest-posttest satu kelompok, 30 mahasiswa program studi pendidikan biologi yang mengikuti mata kuliah profesi kpendidikan  dinilai melalui tes esai berpikir kritis dan kreatif yang diberikan sebelum dan sesudah pembelajaran RFDT berbasis TPACK. Hasilnya menunjukkan peningkatan signifikan pada skor berpikir kritis (dari 62,3 menjadi 77,63) dan skor berpikir kreatif (dari 61,8 menjadi 80,76), dengan p < 0,05. Hasil ini menunjukkan potensi RFDT berbasis TPACK dalam mengembangkan keterampilan berpikir yang esensial, serta mendorong lingkungan belajar yang dinamis dan interaktif. Penelitian selanjutnya dengan sampel yang lebih besar dan desain eksperimental yang lebih kompleks direkomendasikan untuk memperkuat temuan ini.