bluuebunny/crossref_metadata_2025 huggingface dataset:
Magnetic Behavior of an Iron Gluconate/Polyaniline Composite
Authors: Koshikawa Yusuke , Goto Hiromasa
Published: September 2021

Oxidative polymerization conducted the synthesis of polyaniline in the presence of iron gluconate in the water. Iron gluconate is present in the resulting polyaniline (PANI). The PANI composite exhibited multiple signals in electron spin resonance, including half-field resonance of multiple spin states, the center-field resonance of polarons as radical cations in conducting polymer, and a signal from a defect in the main chain. Infrared (IR) absorption spectroscopy measurements confirmed the chemical structure of the PANI composite. The composite exhibits the mixed magnetism of PANI as a conducting polymer and Fe ions in the composite according to superconducting interference device (SQUID) measurements. Combining organic-conjugated polymers and inorganic materials can result in a unique magnetism.
To Grasp the World at a Glance: The Role of Attention in Visual and Semantic Associative Processing
Authors: Gronau Nurit
Published: September 2021

Associative relations among words, concepts and percepts are the core building blocks of high-level cognition. When viewing the world ‘at a glance’, the associative relations between objects in a scene, or between an object and its visual background, are extracted rapidly. The extent to which such relational processing requires attentional capacity, however, has been heavily disputed over the years. In the present manuscript, I review studies investigating scene–object and object–object associative processing. I then present a series of studies in which I assessed the necessity of spatial attention to various types of visual–semantic relations within a scene. Importantly, in all studies, the spatial and temporal aspects of visual attention were tightly controlled in an attempt to minimize unintentional attention shifts from ‘attended’ to ‘unattended’ regions. Pairs of stimuli—either objects, scenes or a scene and an object—were briefly presented on each trial, while participants were asked to detect a pre-defined target category (e.g., an animal, a nonsense shape). Response times (RTs) to the target detection task were registered when visual attention spanned both stimuli in a pair vs. when attention was focused on only one of two stimuli. Among non-prioritized stimuli that were not defined as to-be-detected targets, findings consistently demonstrated rapid associative processing when stimuli were fully attended, i.e., shorter RTs to associated than unassociated pairs. Focusing attention on a single stimulus only, however, largely impaired this relational processing. Notably, prioritized targets continued to affect performance even when positioned at an unattended location, and their associative relations with the attended items were well processed and analyzed. Our findings portray an important dissociation between unattended task-irrelevant and task-relevant items: while the former require spatial attentional resources in order to be linked to stimuli positioned inside the attentional focus, the latter may influence high-level recognition and associative processes via feature-based attentional mechanisms that are largely independent of spatial attention.
Identifying Métiers Using Landings Profiles: An Octopus-Driven Multi-Gear Coastal Fleet
Authors: Szynaka Monika J. , Erzini Karim , Gonçalves Jorge M. S. , Campos Aida
Published: September 2021

The multi-gear coastal vessels in the Algarve (South Portugal) own licenses for various fishing gears. However, it is generally uncertain what gears they use, which is problematic as each individual gear is responsible for unique impacts on the resources and the environment. In this study, landing profiles identified for the multi-gear coastal fleet (2012–2016) were used as support in defining potential métiers using k-mean clustering analysis (CLARA) along with information from past studies on métiers. The results showed that more than 50% of the vessels were engaged in the octopus fishery year-round, using traps, while a small percentage (~13%) were entirely dedicated to clam dredging. In general, gillnets (21%) were used to target monkfish, hake and bastard soles, while trammel nets (6%) were used to target cuttlefish, with some vessels alternating the fishing gears (either seasonally or annually) according to target species. The method for the initial characterization of this fleet’s métiers and its efficiency with limited data is discussed, as well as the utility of this segmentation in support of management advice.
A Simulation Approach to the Definition of the Subsystems Parameters in Small Container Terminals
Authors: Stojaković Maja , Twrdy Elen
Published: September 2021

This article deals with the extremely difficult problem faced by a large number of smaller ports: how to enable small container terminals to simultaneously receive two ships of post-Panamax size, and at the same time provide effective transshipment operations on an individual terminal subsystem, which would enable the fast turnaround of the ship in port and at the same time provide the port the possibility to increase annual traffic. For this purpose, a simulation approach was used in a hypothetical small size container terminal. The performed simulations covered all the berth-yard-berth operations focusing on the correct allocation of transfer mechanization to ensure optimal results on the sea side of the terminal. The results obtained were used to define the key parameters on the basis of which a Decision Support Tool was created. The aim of the Decision Support Tool is to help port operators to identify their current problems quickly and effectively and to give them an insight into the measures that need to be implemented to accommodate two post-Panamax ships at the terminal at the same time.
Hydrodynamic Sensitivity of Moored and Articulated Multibody Offshore Structures in Waves
Authors: Jiang Changqing , el Moctar Ould , Schellin Thomas E.
Published: September 2021

Within the framework of Space@Sea project, an articulated modular floating structure was developed to serve as building blocks for artificial islands. The modularity was one of the key elements, intended to provide the desired flexibility of additional deck space at sea. Consequently, the layout of a modular floating concept may change, depending on its functionality and environmental condition. Employing a potential-flow-based numerical model (i.e., weakly nonlinear Green function solver AQWA), this paper studied the hydrodynamic sensitivity of such multibody structures to the number of modules, to the arrangement of these modules, and to the incident wave angle. Results showed that for most wave frequencies, their hydrodynamic characteristics were similar although the floating platforms consisted of a different number of modules. Only translational horizontal motions, i.e., surge and sway, were sensitive to the incident wave angle. The most critical phenomenon occurred at head seas, where waves traveled perpendicularly to the rotation axes of hinged joints, and the hinge forces were largest. Hydrodynamic characteristics of modules attached behind the forth module hardly changed. The highest mooring line tensions arose at low wave frequencies, and they were caused by second-order mean drift forces. First-order forces acting on the mooring lines were relatively small. Apart from the motion responses and mooring tensions, forces acting on the hinge joints governed the system’s design. The associated results contribute to design of optimal configurations of moored and articulated multibody floating islands.
A Heuristic Approach for Inter-Facility Comparison of Results from Round Robin Testing of a Floating Wind Turbine in Irregular Waves
Authors: Gueydon Sebastien , Judge Frances , Lyden Eoin , O’Shea Michael , Thiebaut Florent , Le Boulluec Marc , Caverne Julien , Ohana Jérémy , Bouscasse Benjamin , Kim Shinwoong , Day Sandy , Dai Saishuai , Murphy Jimmy
Published: September 2021

This paper introduces metrics developed for analysing irregular wave test results from the round robin testing campaign carried out on a floating wind turbine as part of the EU H2020 MaRINET2 project. A 1/60th scale model of a 10 MW floating platform was tested in wave basins in four different locations around Europe. The tests carried out in each facility included decay tests, tests in regular and irregular waves with and without wind thrust, and tests to characterise the mooring system as well as the model itself. While response amplitude operations (RAOs) are a useful tool for assessing device performance in irregular waves, they are not easy to interpret when performing an inter-facility comparison where there are many variables. Metrics that use a single value per test condition rather than an RAO curve are a means of efficiently comparing tests from different basins in a more heuristic manner. In this research, the focus is on using metrics to assess how the platform responds with varying wave height and thrust across different facilities. It is found that the metrics implemented are very useful for extracting global trends across different basins and test conditions.
Numerical Modelling of Oil Spill Transport in Tide-Dominated Estuaries: A Case Study of Humber Estuary, UK
Authors: Eke Chijioke D. , Anifowose Babatunde , Van De Wiel Marco J. , Lawler Damian , Knaapen Michiel A. F.
Published: September 2021

Oil spills in estuaries are less studied and less understood than their oceanic counterparts. To address this gap, we present a detailed analysis of estuarine oil spill transport. We develop and analyse a range of simulations for the Humber Estuary, using a coupled hydrodynamic and oil spill model. The models were driven by river discharge at the river boundaries and tidal height data at the offshore boundary. Satisfactory model performance was obtained for both model calibration and validation. Some novel findings were made: (a) there is a statistically significant (p < 0.05) difference in the influence of hydrodynamic conditions (tidal range, stage and river discharge) on oil slick transport; and (b) because of seasonal variation in river discharge, winter slicks released at high water did not exhibit any upstream displacement over repeated tidal cycles, while summer slicks travelled upstream into the estuary over repeated tidal cycles. The implications of these findings for operational oil spill response are: (i) the need to take cognisance of time of oil release within a tidal cycle; and (ii) the need to understand how the interaction of river discharge and tidal range influences oil slick dynamics, as this will aid responders in assessing the likely oil trajectories.
Ship Trajectory Prediction Based on Bi-LSTM Using Spectral-Clustered AIS Data
Authors: Park Jinwan , Jeong Jungsik , Park Youngsoo
Published: September 2021

According to the statistics of maritime accidents, most collision accidents have been caused by human factors. In an encounter situation, the prediction of ship’s trajectory is a good way to notice the intention of the other ship. This paper proposes a methodology for predicting the ship’s trajectory that can be used for an intelligent collision avoidance algorithm at sea. To improve the prediction performance, the density-based spatial clustering of applications with noise (DBSCAN) has been used to recognize the pattern of the ship trajectory. Since the DBSCAN is a clustering algorithm based on the density of data points, it has limitations in clustering the trajectories with nonlinear curves. Thus, we applied the spectral clustering method that can reflect a similarity between individual trajectories. The similarity measured by the longest common subsequence (LCSS) distance. Based on the clustering results, the prediction model of ship trajectory was developed using the bidirectional long short-term memory (Bi-LSTM). Moreover, the performance of the proposed model was compared with that of the long short-term memory (LSTM) model and the gated recurrent unit (GRU) model. The input data was obtained by preprocessing techniques such as filtering, grouping, and interpolation of the automatic identification system (AIS) data. As a result of the experiment, the prediction accuracy of Bi-LSTM was found to be the highest compared to that of LSTM and GRU.
Method for the Coordination of Referencing of Autonomous Underwater Vehicles to Man-Made Objects Using Stereo Images
Authors: Bobkov Valery , Kudryashov Alexey , Inzartsev Alexander
Published: September 2021

The use of an autonomous underwater vehicle (AUV) to inspect underwater industrial infrastructure requires the precise, coordinated movement of the AUV relative to subsea objects. One significant underwater infrastructure system is the subsea production system (SPS), which includes wells for oil and gas production, located on the seabed. The present paper suggests a method for the accurate navigation of AUVs in a distributed SPS to coordinate space using video information. This method is based on the object recognition and computation of the AUV coordinate references to SPS objects. Stable high accuracy during the continuous movement of the AUV in SPS space is realized through the regular updating of the coordinate references to SPS objects. Stereo images, a predefined geometric SPS model, and measurements of the absolute coordinates of a limited number of feature points of objects are used as initial data. The matrix of AUV coordinate references to the SPS object coordinate system is computed using 3D object points matched with the model. The effectiveness of the proposed method is estimated based on the results of computational experiments with virtual scenes generated in the simulator for AUV, and with real data obtained by the Karmin2 stereo camera (Nerian Vision, Stuttgart, Germany) in laboratory conditions.
Proteome Response of Meretrix Bivalves Hepatopancreas Exposed to Paralytic Shellfish Toxins Producing Dinoflagellate Gymnodinium catenatum
Authors: Chan Kin-Ka , Tam Nora Fung-Yee , Ng Christie , Kwok Celia Sze-Nga , Xu Steven Jing-Liang , Sze Eric Tung-Po , Lee Fred Wang-Fat
Published: September 2021

Paralytic shellfish toxins (PSTs) contamination of seafood has become a growing global problem. However, the molecular response of bivalves, some of the most popular seafoods, to PSP toxins has seldom been reported and the underlying molecular mechanisms of the interactions between Meretrix meretrix bivalves and PSTs-producing dinoflagellates are scarcely known. This study compared the protein expression profiles between PSP toxin-contaminated and non-PSP toxin contaminated M. meretrix, determined proteome responses and identified potential biomarkers based on feeding experiments. Results showed that the content of total PSP toxins in contaminated bivalves was 40.63 ± 4.08 μg saxitoxin (STX) equivalents per gram, with 95.3% in hepatopancreas, followed by gill (1.82%) and foot (1.79%). According to two-dimensional gel electrophoresis (2-DE), 15 differentially expressed proteins (at least 2-fold difference) between the hepatopancreas of bivalves with and without PSP toxins were detected. Eight of them were successfully identified by MALDI-TOF MS. These were catalase, protein ultraspiracle homolog, G2 and S phase-expression protein, paramyosin, Mn-superoxide dismutase, response regulator receiver domain-containing protein, sarcoplasmic calcium-binding protein and major facilitator superfamily transporters. The differences in the expression levels of the last three proteins involving in cell signaling, structure and membrane transport were 4.2, 5.3 and 4.9-fold, respectively. These proteins could be further developed as potential biomarkers. The other two up-regulated proteins, Mn-superoxide dismutase and catalase, were involved in cell defence mechanisms against oxidative stress, suggesting PSP toxin acts as xenobiotics and poses oxidative stress in bivalves. This study gives insights into the response of bivalves to PSP toxin-producing dinoflagellate at the proteomic level and the potential of using 2-DE to develop specific protein markers in bivalves.
Entomotoxic Activity of the Extracts from the Fungus, Alternaria tenuissima and Its Major Metabolite, Tenuazonic Acid
Authors: Salimova Dilara , Dalinova Anna , Dubovik Vsevolod , Senderskiy Igor , Stepanycheva Elena , Tomilova Oksana , Hu Qiongbo , Berestetskiy Alexander
Published: September 2021

The study of fungal antibiotics in their competitive interactions with arthropods may lead to the development of novel biorational insecticides. Extracts of Alternaria tenuissima MFP253011 obtained using various methods showed a wide range of biological activities, including entomotoxic properties. Analysis of their composition and bioactivity allowed us to reveal several known mycotoxins and unidentified compounds that may be involved in the entomotoxic activity of the extracts. Among them, tenuazonic acid (TeA), which was the major component of the A. tenuissima extracts, was found the most likely to have larvicidal activity against Galleria mellonella. In the intrahaemocoel injection bioassay, TeA was toxic to G. mellonella and of Zophobas morio with an LT50 of 6 and 2 days, respectively, at the level of 50 µg/larva. Administered orally, TeA inhibited the growth of G. mellonella larvae and caused mortality of Acheta domesticus adults (LT50 7 days) at a concentration of 250 µg/g of feed. TeA showed weak contact intestinal activity against the two phytophages, Tetranychus urticae and Schizaphis graminum, causing 15% and 27% mortality at a concentration of 1 mg/mL, respectively. TeA was cytotoxic to the Sf9 cell line (IC50 25 µg/mL). Thus, model insects such as G. mellonella could be used for further toxicological characterization of TeA.
In Vitro Effects of Leaf Extracts from Brassica rapa on the Growth of Two Entomopathogenic Fungi
Authors: Cerritos-Garcia Daniel G. , Avery Pasco B. , Martini Xavier , Candian Valentina , Cano Liliana M. , Cave Ronald D.
Published: September 2021

This study aimed to determine the inhibitive or stimulatory effects of leaf extracts from two Brassica rapa subspecies on the hyphal growth of two well-known entomopathogenic fungi, Cordyceps fumosorosea and Beauveria bassiana. Extract concentrations of 50, 25, and 10% w/v based on leaf fresh weight were prepared from turnip (B. rapa subspecies rapa) and bok choy (B. rapa subspecies chinensis) leaves. Each concentration was individually incorporated into potato dextrose agar plates for in vitro bioassays. The center of each plate was inoculated with 20 µL of a fungal suspension that was allowed 24 h to soak into the agar before sealing the plates and incubating them at 25 °C under a 14-h photophase. The fungal colony perimeter was marked 5 days after inoculation on two perpendicular lines drawn on the bottom of each plate. Radial colony growth was measured from 4 marks per plate 5, 10, and 15 days later. Radial growth rates for both fungi were 1.3–2.0 and 0.9–1.4 times faster with bok choy and turnip extracts, respectively, at the 25% and 50% concentrations compared to the no-extract control treatment. Therefore, bok choy and turnip leaf extracts can stimulate entomopathogenic fungus growth within 15 days. Biochemical compounds in the extracts include sesquiterpenes, α-copaene, β-selinene, γ-gurjunene, calamenene, cubenene, and α-calacorene.
Insights into the Role of Fungi in Pine Wilt Disease
Authors: Vicente Cláudia S. L. , Soares Miguel , Faria Jorge M. S. , Ramos Ana P. , Inácio Maria L.
Published: September 2021

Pine wilt disease (PWD) is a complex disease that severely affects the biodiversity and economy of Eurasian coniferous forests. Three factors are described as the main elements of the disease: the pinewood nematode (PWN) Bursaphelenchus xylophilus, the insect-vector Monochamus spp., and the host tree, mainly Pinus spp. Nonetheless, other microbial interactors have also been considered. The study of mycoflora in PWD dates back the late seventies. Culturomic studies have revealed diverse fungal communities associated with all PWD key players, composed frequently of saprophytic fungi (i.e., Aspergillus, Fusarium, Trichoderma) but also of necrotrophic pathogens associated with bark beetles, such as ophiostomatoid or blue-stain fungi. In particular, the ophiostomatoid fungi often recovered from wilted pine trees or insect pupal chambers/tunnels, are considered crucial for nematode multiplication and distribution in the host tree. Naturally occurring mycoflora, reported as possible biocontrol agents of the nematode, are also discussed in this review. This review discloses the contrasting effects of fungal communities in PWD and highlights promising fungal species as sources of PWD biocontrol in the framework of sustainable pest management actions.
Physical Inactivity: A Modifiable Risk Factor for Morbidity and Mortality in Kidney Transplantation
Authors: Ponticelli Claudio , Favi Evaldo
Published: September 2021

In patients with chronic kidney disease, sedentary behavior is widely recognized as a significant risk factor for cardiovascular disease, diabetes, obesity, osteoporosis, cancer, and depression. Nevertheless, the real impact of physical inactivity on the health of kidney transplant (KT) recipients remains uncertain. Over the last decade, there has been a renewed interest in exploring the effects of regular physical exercise on transplant-related outcomes. There is now mounting evidence that physical activity may reduce the burden of cardiovascular risk factors, preserve allograft function, minimize immunosuppression requirement, and ameliorate the quality of life of KT recipients. Many positive feedbacks can be detected in the early stages of the interventions and with a minimal exercise load. Despite these encouraging results, the perceived role of physical activity in the management of KT candidates and recipients is often underrated. The majority of trials on exercise training are small, relatively short, and focused on surrogate outcomes. While waiting for larger studies with longer follow-up, these statistical limitations should not discourage patients and doctors from initiating exercise and progressively increasing intensity and duration. This narrative review summarizes current knowledge about the deleterious effects of physical inactivity after KT. The benefits of regular physical exercise are also outlined.
Dialectical Behaviour Therapy Improves Emotion Dysregulation Mainly in Binge Eating Disorder and Bulimia Nervosa: A Systematic Review and Meta-Analysis
Authors: Rozakou-Soumalia Natalia , Dârvariu Ştefana , Sjögren Jan Magnus
Published: September 2021

Emotion dysregulation is a transdiagnostic phenomenon in Eating Disorders (ED), and Dialectical Behaviour Therapy (DBT) (which was developed for reducing dysregulated emotions in personality disorders) has been employed in patients with ED. This systematic review and meta-analysis investigated whether the effect of DBT was stronger on emotion dysregulation, general psychopathology, and Body Mass Index (BMI) in participants with ED, when compared to a control group (active therapy and waitlist). Eleven studies were identified in a systematic search in accordance with PRISMA guidelines. Most studies included participants with Binge Eating Disorder (BED) (n = 8), some with Bulimia Nervosa (BN) (n = 3), and only one with Anorexia Nervosa (AN). The pooled effect of DBT indicated a greater improvement in Emotion Regulation (ER) (g = −0.69, p = 0.01), depressive symptoms (g = −0.33, p < 0.00001), ED psychopathology (MD = −0.90, p = 0.005), Objective Binge Episodes (OBE) (MD = −0.27, p = 0.003), and BMI (MD = −1.93, p = 0.01) compared to the control group. No improvement was detected in eating ER following DBT (p = 0.41). DBT demonstrated greater efficacy compared with the control group in improving emotion dysregulation, ED psychopathology, and BMI in ED. The limitations included the small number of studies and high variability.
Access to Prenatal Testing and Ethically Informed Counselling in Germany, Poland and Russia
Authors: Orzechowski Marcin , Timmermann Cristian , Woniak Katarzyna , Kosenko Oxana , Mikirtichan Galina Lvovna , Lichtshangof Alexandr Zinovievich , Steger Florian
Published: September 2021

The development of new methods in the field of prenatal testing leads to an expansion of information that needs to be provided to expectant mothers. The aim of this research is to explore opinions and attitudes of gynecologists in Germany, Poland and Russia towards access to prenatal testing and diagnostics in these countries. Semi-structured interviews were conducted with n = 18 gynecologists in Germany, Poland and Russia. The interviews were analyzed using the methods of content analysis and thematic analysis. Visible in all three countries is a connection of prenatal medicine with the politically and socially contentious issue of pregnancy termination. Respondents in Poland and Russia concentrated on the topic of inadequate resources. Quality of information for expectant mothers is an important point in all three countries. Only in Germany was the issue of language barriers in communication raised. With regard to non-invasive prenatal testing (NIPT) respondents in Germany focused on the ethical issues of routinization of testing; in Poland and Russia they concentrated on fair access to NIPT. Challenges in all three countries arise from structural factors such as imprecise and prohibitive regulations, lack of resources or organization of healthcare services. These should be addressed on a political and medico-ethical level.
Predictors of the CD24/CD11b Biomarker among Healthy Subjects
Authors: Shapira Shiran , Aiger Gal , Ohayon Amitay , Kazanov Dina , Mdah Fatin , Shimon Marina Ben , Hay-Levy Mori , Banon Lian , Laskov Ido , Mashiah Jacob , Lev-Ari Shahar , Arber Nadir
Published: September 2021

The CD24 gene has raised considerable interest in tumor biology as a new prognostic factor and a biomarker for the early detection of cancer. There are currently no studies that assess predictors of CD24 in blood tests among healthy individuals. Our aims were (1) to evaluate predictors of the CD24/CD11b biomarker among healthy subjects and (2) to assess CD24/CD11b levels of participants with and without benign tumors. Our cohort included 1640 healthy subjects, aged 20–85, recruited at the Health Promotion and Integrated Cancer Prevention Center (ICPC) in the Tel Aviv Medical Center. Eligible subjects completed a detailed questionnaire on medical history and other epidemiologic information. CD24/CD11b expression in peripheral blood leukocytes (PBLs) obtained from blood samples of participants was analyzed by flow cytometry. Our results showed that the average levels of CD24/CD11b in healthy patients (22.8 ± 9.3) was statistically significant lower compared to subjects with benign cancers (26.1 ± 10.5, p < 0.001). Our multivariable analysis demonstrated that elevated levels of CRP (coefficient β: 1.98, p = 0.011) were significantly associated with high levels of CD24/CD11b expression among healthy participants. Other risk factors of cancer were not associated with elevated CD24 levels among healthy subjects. In conclusion, our findings may assist in further development and optimization of the CD24/CD11b biomarker to serve as a cancer screening test for early detection of cancer among the healthy population.
Does the Money Multiplier Hold in Pacific Island Countries? The Case of Papua New Guinea
Authors: Ofoi Mark , Sharma Parmendra
Published: September 2021

This is the first study to systematically assess the significance of the standard money multiplier vis-à-vis the bank credit transmission channel in the case of Pacific Island Economies, focusing on Papua New Guinea. The vector autoregressive model comprising six variables—interest rate, inflation rate, loans, deposits, reserve money, and real output—was estimated using quarterly data for the period 1980q1 to 2017q4. We applied the ordinary least squares (OLS) method to estimate the system of vector autoregressions (VARs). The estimation was conducted for the full and sub-sample periods. From the impulse response functions generated, the results suggest that the money multiplier does not hold and that the transmission to bank credit appears weak. It seems that the ability of the Central Bank to make loanable funds available through its conduct of monetary policy may not enhance private sector credit. On the other hand, there appears to be a significant and positive association between bank deposits and credit, suggesting that bank deposits and credit are endogenous and demand driven.
Risk Assessment of Express Delivery Service Failures in China: An Improved Failure Mode and Effects Analysis Approach
Authors: Shan Hongmei , Tong Qiaoqiao , Shi Jing , Zhang Qian
Published: September 2021

With the rapid growth of express delivery industry, service failure has become an increasingly pressing issue. However, there is a lack of research on express service failure risk assessment within the Failure Mode and Effects Analysis (FMEA) framework. To address the research gap, we propose an improved FMEA approach based on integrating the uncertainty reasoning cloud model and the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) method. The cloud model describing randomness and fuzziness in uncertainty environment is adopted to achieve the transformation between the qualitative semantic evaluation of occurrence (O), severity (S), and detection (D) risk factors of FMEA and the quantitative instantiation and set up the comprehensive cloud of risk assessment matrix for express delivery service failure (EDSF). The TOPSIS method calculates and ranks the relative closeness coefficients of EDSF mode. Finally, the rationality and applicability of the proposed method are demonstrated by an empirical study for the express delivery service in China. It is found that among 18 express delivery service failure modes, six service failure modes with high risk are mainly located in the processing and delivery stages, while six service failures with the relatively low risk are involved in the picking-up and transportation stages. This study provides insight on how to explore the risk evaluation of express delivery service failure, and it helps express delivery firms to identify the key service failure points, develop the corresponding service remedy measures, reduce the loss from service failures, and improve the service quality.
Singapore vs. the ‘Singapore of Africa’—Different Approaches to Managing Urban Agriculture
Authors: Górna Ada , Górny Krzysztof
Published: September 2021

Through structured comparison, this article seeks to present the different approaches to urban agriculture in the cities of Singapore and Kigali. The former is seen as a model ‘smart city’ worth following worldwide, while the latter is frequently referred to as the ‘Singapore of Africa’. The research conducted was divided into two stages. The first one was desk-based and included the analysis of satellite and aerial images along with the analysis of legal documents regarding land ownership and urban agriculture management. The second one was based on field work carried out in 2019 in both cities and comprised the mapping of areas encompassed by urban agriculture, the collection of photographic documentation, field observations, as well as semi-structured interviews. The research was summarized in line with a comparative analysis of institutional and legal framework of urban agriculture and policy towards its development; spatial features of urban agriculture, including distribution, location, and area; as well as inherent features of urban agriculture, including systems of production, main crops, production methods, and functions. The process makes it clear that despite the fact that urban agriculture is considered in planning documents of both cities, the scale of the activity and the approach towards it differ markedly. In Singapore, the authorities support mainly the high-technology and land-efficient solutions, with other, low-profit forms of agricultural activity being pushed out from the urban space. In turn, in Kigali, where the scale of agricultural activity is incomparably greater, the inhabitants enjoy a certain freedom to make use of unused land in cultivation, which increases their food security and enhances their ability to cope with external stresses.
New Round of Collective Forest Rights Reform, Forestland Transfer and Household Production Efficiency
Authors: Yu Jinna , Wei Yiming , Fang Wei , Liu Zhen , Zhang Yujie , Lan Jing
Published: September 2021

The purpose of this paper was to analyze the influence mechanism of the new round of Collective Forest Rights Reform (CFRR) on farmers’ production efficiency from the perspective of forestland transfer. Based on the panel data of field investigation in Jiangxi Province, a panel logit model was used to verify whether the new round of CFRR has affected farmers’ forestland circulation behavior. The results showed that the new round of CFRR has played a significant role in promoting forestland circulation. Secondly, the non-parametric DEA method was used to estimate the technical, scale, and comprehensive efficiency of households. DID and panel quantile models were constructed to analyze the impact of forestland inflow policy and forestland outflow policy effects on rural household productivity. The regression results showed that the effect of forestland inflow has had a significantly positive impact on scale and comprehensive efficiency, but it only had a significant effect on technical efficiency in the 0.1 quartile. The effect of forestland outflow was not found to be significant for technical, scale, and comprehensive efficiency, but it was found to be negative for technical efficiency in the 0.75 quartile and negative for scale efficiency in the 0.5 and 0.75 quantiles.
A Synthesis of Land Use/Land Cover Studies: Definitions, Classification Systems, Meta-Studies, Challenges and Knowledge Gaps on a Global Landscape
Authors: Nedd Ryan , Light Katie , Owens Marcia , James Neil , Johnson Elijah , Anandhi Aavudai
Published: September 2021

Land is a natural resource that humans have utilized for life and various activities. Land use/land cover change (LULCC) has been of great concern to many countries over the years. Some of the main reasons behind LULCC are rapid population growth, migration, and the conversion of rural to urban areas. LULC has a considerable impact on the land-atmosphere/climate interactions. Over the past two decades, numerous studies conducted in LULC have investigated various areas of the field of LULC. However, the assemblage of information is missing for some aspects. Therefore, to provide coherent guidance, a literature review to scrutinize and evaluate many studies in particular topical areas is employed. This research study collected approximately four hundred research articles and investigated five (5) areas of interest, including (1) LULC definitions; (2) classification systems used to classify LULC globally; (3) direct and indirect changes of meta-studies associated with LULC; (4) challenges associated with LULC; and (5) LULC knowledge gaps. The synthesis revealed that LULC definitions carried vital terms, and classification systems for LULC are at the national, regional, and global scales. Most meta-studies for LULC were in the categories of direct and indirect land changes. Additionally, the analysis showed significant areas of LULC challenges were data consistency and quality. The knowledge gaps highlighted a fall in the categories of ecosystem services, forestry, and data/image modeling in LULC. Core findings exhibit common patterns, discrepancies, and relationships from the multiple studies. While literature review as a tool showed similarities among various research studies, our results recommend researchers endeavor to perform further synthesis in the field of LULC to promote our overall understanding, since research investigations will continue in LULC.
The Causal Relationship between Endothelin-1 and Hypertension: Focusing on Endothelial Dysfunction, Arterial Stiffness, Vascular Remodeling, and Blood Pressure Regulation
Authors: Kostov Krasimir
Published: September 2021

Hypertension (HTN) is one of the most prevalent diseases worldwide and is among the most important risk factors for cardiovascular and cerebrovascular complications. It is currently thought to be the result of disturbances in a number of neural, renal, hormonal, and vascular mechanisms regulating blood pressure (BP), so crucial importance is given to the imbalance of a number of vasoactive factors produced by the endothelium. Decreased nitric oxide production and increased production of endothelin-1 (ET-1) in the vascular wall may promote oxidative stress and low-grade inflammation, with the development of endothelial dysfunction (ED) and increased vasoconstrictor activity. Increased ET-1 production can contribute to arterial aging and the development of atherosclerotic changes, which are associated with increased arterial stiffness and manifestation of isolated systolic HTN. In addition, ET-1 is involved in the complex regulation of BP through synergistic interactions with angiotensin II, regulates the production of catecholamines and sympathetic activity, affects renal hemodynamics and water–salt balance, and regulates baroreceptor activity and myocardial contractility. This review focuses on the relationship between ET-1 and HTN and in particular on the key role of ET-1 in the pathogenesis of ED, arterial structural changes, and impaired vascular regulation of BP. The information presented includes basic concepts on the role of ET-1 in the pathogenesis of HTN without going into detailed analyses, which allows it to be used by a wide range of specialists. Also, the main pathological processes and mechanisms are richly illustrated for better understanding.
Anemia in Sports: A Narrative Review
Authors: Damian Marc-Tudor , Vulturar Romana , Login Cristian Cezar , Damian Laura , Chis Adina , Bojan Anca
Published: September 2021

Recent years have brought about new understandings regarding the pathogenesis of anemia in sports. From hemodilution and redistribution considered to contribute to the so-called “sports anemia” to iron deficiency caused by increased demands, dietary restrictions, decreased absorption, increased losses, hemolysis, and sequestration, to genetic determinants of different types of anemia (some related to sport), the anemia in athletes deserves a careful and multifactorial approach. Dietary factors that reduce iron absorption (e.g., phytate, polyphenols) and that augment iron’s bioavailability (e.g., ascorbic acid) should be considered. Celiac disease, more prevalent in female athletes, may underlie an unexplained iron deficiency anemia. Iron loss during exercise occurs in several ways: sweating, hematuria, gastrointestinal bleeding, inflammation, and intravascular and extravascular hemolysis. From a practical point of view, assessing iron status, especially in the athletes at risk for iron deficiency (females, adolescents, in sports with dietary restrictions, etc.), may improve the iron balance and possibly the performance. Hemoglobin and serum ferritin are measures that are easily employable for the evaluation of patients’ iron status. Cutoff values should probably be further assessed with respect to the sex, age, and type of sport. A healthy gut microbiome influences the iron status. Athletes at risk of iron deficiency should perform non-weight-bearing, low-intensity sports to avoid inducing hemolysis.
Seminal Plasma Protein N-Glycan Peaks Are Potential Predictors of Semen Pathology and Sperm Chromatin Maturity in Men
Authors: Maric Tihana , Katusic Bojanac Ana , Matijevic Ana , Ceppi Marcello , Bruzzone Marco , Evgeni Evangelini , Petrovic Tea , Wójcik Iwona , Trbojevic-Akmacic Irena , Lauc Gordan , Jezek Davor , Fucic Aleksandra
Published: September 2021

Background: Male infertility is increasingly becoming a health and demographic problem. While it may originate from congenital or acquired diseases, it can also result from environmental exposure. Hence, the complexity of involved molecular mechanisms often requires a multiparametric approach. This study aimed to associate semen parameters with sperm DNA fragmentation, chromatin maturity and seminal plasma protein N-glycosylation. Methods: The study was conducted with 166 participants, 20–55 y old, 82 normozoospermic and 84 with pathological diagnosis. Sperm was analyzed by Halosperm assay and aniline blue staining, while seminal plasma total protein N-glycans were analyzed by ultra-high-performance liquid chromatography. Results: Sperm DNA fragmentation was significantly increased in the pathological group and was inversely correlated with sperm motility and viability. Seminal plasma total protein N-glycans were chromatographically separated in 37 individual peaks. The pattern of seminal plasma N-glycan peaks (SPGP) showed that SPGP14 significantly differs between men with normal and pathological semen parameters (p < 0.001). The multivariate analysis showed that when sperm chromatin maturity increases by 10%, SPGP17 decreases by 14% while SPGP25 increases by 25%. Conclusion: DNA integrity and seminal plasma N-glycans are associated with pathological sperm parameters. Specific N-glycans are also associated with sperm chromatin maturity and have a potential in future fertility research and clinical diagnostics.
The Procoagulant Activity of Emoxilane®: A New Appealing Therapeutic Use in Epistaxis of the Combination of Sodium Hyaluronate, Silver Salt, α-tocopherol and D-panthenol
Authors: Belvedere Raffaella , Novizio Nunzia , Eletto Daniela , Porta Amalia , Bagnulo Antonino , Cerciello Andrea , Di Maio Umberto , Petrella Antonello
Published: September 2021

Epistaxis is one of the most frequent hemorrhages resulting from local or systemic factors. Its management without hospitalization has prompted an interest in locally applied hemostatic agents. Generally, the therapy approaches involve sprays or creams acting as a physical barrier, even used as tampons or gauze. In this study, we have investigated the activity of Emoxilane®, a combination of sodium hyaluronate, silver salt, α-tocopherol acetate and D-panthenol, which is known to be able to separately act in a different biological manner. Our in vitro results, obtained on endothelial and nasal epithelial cells, have shown that the association of these molecules presented a notable antioxidant activity mainly due to the α-tocopherol and D-panthenol and a significant antimicrobial role thanks to the silver compound. Moreover, remarkable hemostatic activity was found by evaluating plasmin inhibition attributable to the sodium hyaluronate. Interestingly, on human plasma, we have confirmed that Emoxilane® strongly induced the increase of thrombin levels. These data suggest that the use of this association could represent an appealing pharmacological approach to actively induce hemostasis during epistaxis. Our future perspective will aim to the creation of a formulation for an easy topical application in the nose which is able to contrast the bleeding.
Computational Insights into the Interaction between Cytoadherence Receptor gC1qR and the DBLβ12 Domain of a Plasmodium falciparum PfEMP1 Ligand
Authors: Bakri Rowaida , Rehan Mohd , Shamshad Hina , Hafiz Abdul
Published: September 2021

Human receptor gC1qR is a 32 kD protein that mediates the cytoadherence of Plasmodium falciparum-infected erythrocytes (IEs) to human brain microvascular endothelial cells (HBMEC) and platelets. The cytoadherence of IEs to gC1qR has been associated with severe malaria symptoms. The cytoadherence to gC1qR is mediated by the Duffy binding-like β12 (DBLβ12) domain of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), PFD0020c. Here, we report the structural insights into the binding of the DBLβ12 domain of PfEMP1 with the human receptor gC1qR using computational methods. A molecular model of the DBLβ12 domain was generated and used for protein–protein docking with the host receptor gC1qR. The protein–protein docking revealed that the DBLβ12 asymmetrically interacts with two subunits of the gC1qR trimer at the solution face of gC1qR. A total of 21 amino acid residues of DBLβ12 interact with 26 amino acid residues in the gC1qR trimer through 99 nonbonding interactions and 4 hydrogen bonds. Comparative analysis of binding sites on the DBL domain fold for the two receptors gC1qR and ICAM1 showed that the two sites are distinct. This is the first study that provides structural insights into DBLβ12 binding with its receptor gC1qR and may help in designing novel antisevere malaria interventions.
Helium Bubbles and Blistering in a Nanolayered Metal/Hydride Composite
Authors: Taylor Caitlin A. , Lang Eric , Kotula Paul G. , Goeke Ronald , Snow Clark S. , Wang Yongqiang , Hattar Khalid
Published: September 2021

Helium is insoluble in most metals and precipitates out to form nanoscale bubbles when the concentration is greater than 1 at.%, which can alter the material properties. Introducing controlled defects such as multilayer interfaces may offer some level of helium bubble management. This study investigates the effects of multilayered composites on helium behavior in ion-implanted, multilayered ErD2/Mo thin film composites. Following in-situ and ex-situ helium implantation, scanning and transmission electron microscopy showed the development of spherical helium bubbles within the matrix, but primarily at the layer interfaces. Bubble linkage and surface blistering is observed after high fluence ex-situ helium implantation. These results show the ability of metallic multilayers to alter helium bubble distributions even in the presence of a hydride layer, increasing the lifetime of materials in helium environments.
Effect of Amorphous Metallic Fibers on Strength and Drying Shrinkage of Mortars with Steel Slag Aggregate
Authors: Kim Ji-Hwan , Bae Sung-Ho , Choi Se-Jin
Published: September 2021

Recently, with increasingly stringent environmental regulations and the depletion of natural aggregate resources, high-quality aggregates have become scarce. Therefore, significant efforts have been devoted by the construction industry to improve the quality of concrete and achieve sustainable development by utilizing industrial by-products and developing alternative aggregates. In this study, we use amorphous metallic fibers (AMFs) to enhance the performance of mortar with steel slag aggregate. Testing revealed that the 28-day compressive strength of the sample with steel slag aggregate and AMFs was in the range of 48.7–50.8 MPa, which was equivalent to or higher than that of the control sample (48.7 MPa). The AMFs had a remarkable effect on improving the tensile strength of the mortar regardless of the use of natural aggregates. With AMFs, the drying shrinkage reduction rate of the sample with 100% steel slag aggregate was relatively higher than that of the sample with 50% natural fine aggregate. Furthermore, the difference in the drying shrinkage with respect to the amount of AMFs was insignificant. The findings can contribute to sustainable development in the construction industry.