bluuebunny/crossref_metadata_2025 huggingface dataset:
The well-being of people with anterior cruciate ligament rupture-related post-traumatic osteoarthritis in Aotearoa New Zealand
Authors: O'Brien Daniel William , Rabey Martin , Reid Duncan , Ellis Richard , Uluinayau Tammi Wilson , Whittaker Jackie L. Whittaker Jackie L.
Published: November 2024

Background
Anterior cruciate ligament (ACL) ruptures are a potent risk factor for post-traumatic knee osteoarthritis (PTOA). Annually, in Aotearoa New Zealand, approximately 2,500 people under the age of 30 undergo ACL reconstruction surgery. Due to the young age of injury and surgery, many develop osteoarthritis before age 50 and have a higher likelihood of requiring total knee replacement compared to the general population. This study aimed to gain insight into the medium- to long-term impacts of ACL rupture on people's well-being in Aotearoa New Zealand, by exploring their lived experiences five or more years post-injury.
Method
In this Interpretive Description observational study, we conducted semi-structured interviews with people who had ruptured their ACL and had or were at risk of developing PTOA. Analysis was conducted guided by Braun and Clarke’s Reflexive Thematic Analysis.
Findings:
12 people (7 women, median age 49.5 [25–62] years) were interviewed. Three themes were generated from the data: 1) Nobody Ever Told Me…, 2) The Post-Rehabilitation Void, and 3) The Elephant in the Room: The Psychosocial Impact. Participants commonly described fear, grief and long-term psychological impacts, and most reported wanting to know more about the long-term management of their knees.
Conclusion and Impact:
The study highlights opportunities to provide better long-term support and management, improve outcomes, and reduce the burden on these individuals. ACL injury can profoundly impact people's lives in the long term. Better education, support services, and consideration of psychosocial factors are needed. Addressing identified barriers could reduce the individual and socioeconomic burden of PTOA for New Zealanders. Future research involving stakeholders must establish acceptable long-term management programs tailored to the local population.
When Q Fever Strikes Twice; Meningoencephalitis and Hepatitis B Reactivation in the Setting of Advanced HIV Infection: A case report and review of the literature
Authors: Alshanaqeeti Shatha , Akshita Jain , Sharma Soumit , Lyke Kirsten
Published: November 2024

Background
Q fever is an emerging zoonotic disease caused by Coxiella burnetii. Its unique structure allows it to survive environmental stress as well as the intracellular acidic environment. C. burnetti also evades the immune system further contributing to it’s virulence. Human infection occurs following inhalation of fomites or contact with body fluids from infected animals. Q fever manifest in various clinical forms, with acute presentations often involving nonspecific febrile illness, hepatitis, or pneumonia. Meningioencephalitis is rare and associated with increased mortality.
Case Presentation
We present a 30-year-old male who presented with an altered mental status, fever, and acute hepatitis, found to have a new diagnosis of advanced HIV infection and hepatitis B. Q fever serologies were consistent with acute Q fever and he was treated for Q fever aseptic meningioencephalitis with Doxycyline with significant improvement in fever and mental status.
Conlusion
The findings in this case highlight the interplay of Q fever with HIV infection and its possible role in hepatitis B reactivation. Infection with C. burnetti results in CD4 cell activation and cytokine release, an effect that is impaired in patients with advanced HIV/AIDS. In this review, we explore the pathophysiology, diagnostic challenges, and management of Q fever in advanced HIV and how that interplays with hepatitis B co-infection. Further research is needed to explore the relationship between Q fever, HIV, and hepatitis B.
A New Accurate and Robust Method Based on Deep Neural Networks for Fault Location in HVDC Systems
Authors: Merlin Victor Luiz , Santos Ricardo Caneloi , Pavani Ahda , Vieira José Carlos Melo
Published: November 2024

This paper proposes a new method based on Deep Neural Networks and direct-current (DC) voltage signal for fault location in High Voltage Direct Current (HVDC) systems. The proposed solution uses only local measurements and a reasonable sampling frequency, which ensures its applicability. Performing an intelligent signal processing, the power system reliability and availability can be improved, without additional devices or communication links. The proposed method takes advantage of the high capability of neural networks for pattern recognition, associating the frequency spectrum of faulted signals to specific fault locations. The training process is detailed and the definition of the most suited neural network architecture is presented. The method is validated by using different HVDC systems, different fault types and fault resistances. The results reveal the good performance and robustness of the proposed method and its potential for application for real scenarios.
WITHDRAWN: Housing price prediction using numeric and textual data in Karachi
Authors: KHAN MUHAMMAD KASHIF , KIRCHBERGER MARTINA
Published: November 2024

The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
I-Viewer: An Online Digital Pathology Analysis Platform with Agentic-RAG AI Copilot
Authors: Rong Ruichen , Luo Danni , Gu Zifan , Quan Peiran , Villanueva-Miranda Ismael , Wang Jonathan , Yang Shengjie , Chi Zhikai , Leavey Patrick , Yang Donghan M. , Xie Yang , Zhan Xiaowei , Xiao Guanghua
Published: November 2024

Digital pathology has seen significant advancements in artificial intelligence (AI) applications. However, challenges persist in integrating these solutions into digital pathology platforms for human and AI collaborations. We introduce I-Viewer, an online AI Copilot framework designed to facilitate real-time human-AI and human-human collaboration for digital pathology analysis. The I-Viewer platform enables precise annotations and descriptions from tissue to the nuclei level through an Agentic-Retrieval Augmented Generation (RAG) system. By leveraging agents' outputs as reference points, aggregating information through the RAG system, and incorporating Large Language Models (LLM) for human feedback and refinement, I-Viewer sets a new standard for collaborative and accurate digital pathology analysis. We demonstrate I-Viewer's effectiveness on different pathology tasks using three datasets across different types of cancers, including non-small cell lung cancer, breast cancer, and colorectal cancer. The results show that I-Viewer achieves significant improvements in annotation speed and accuracy for pathology tasks, such as detecting cell morphology, cellular structures, and tumor growth patterns, outperforming current individual foundation models. Through its advanced AI agents, collaborative features, and LLM integrations, I-Viewer optimizes diagnostic workflows in clinical care and biomedical research.
Genome-wide methylomics identifies pre-existing DNA methylation signatures in the prefrontal cortex of alcohol-naïve rhesus monkeys defining neural vulnerability for future risky ethanol consumption.
Authors: Cervera-Juanes Rita , Zimmerman Kip D. , Wilhelm Larry , Lowe Clara Christine , Gonzales Steven W. , Carlson Tim , Hitzemann Robert , Ferguson Betsy M. , Grant Kathy A.
Published: November 2024

Alcohol use disorder (AUD) is a highly prevalent, complex, multifactorial, and heterogeneous disorder. Currently, 11% and 30% of adults meet the criteria for past-year and lifetime AUD, respectively. Identification of the molecular mechanisms underlying risk for AUD would facilitate effective deployment of personalized interventions. Previous studies using rhesus monkeys and rats, have demonstrated that individuals with low cognitive flexibility and a predisposition towards habitual behaviors show an increased risk for future heavy drinking. Further, low cognitive flexibility is associated with reduced dorsolateral prefrontal cortex (dlPFC) function in rhesus monkeys. To explore the underlying unique molecular signatures that increase risk for chronic heavy drinking, a genome-wide DNA methylation (DNAm) analysis of the alcohol-naïve dlPFC-A46 biopsy prior to chronic alcohol self-administration was conducted in 11 male macaques. The DNAm profile provides a molecular snapshot of the alcohol-naïve dlPFC, with mapped genes and associated signaling pathways that vary across individuals. The analysis identified 1,463 differentially methylated regions related to unique genes that were strongly associated with a range of daily voluntary ethanol intakes consumed over 6 months. These findings translate behavioral phenotypes into neural markers of risk for AUD, and therefore hold promise for parallel discoveries in risk for other disorders involving impaired cognitive flexibility.
Application of Mini-CEX combined with student-standardized patient in rehabilitation medicine residents’ standardized training
Authors: Zeng Yaqin , Cheng Ruidong , Shao Zhouli , Zhang Li
Published: November 2024

Background: The mini clinical evaluation exercise (Mini-CEX) is widely recognized as an effective measure for standardized training for resident physicians (RST) in European and American countries. However, in China, the Mini-CEX evaluation is limited to clinical patients. No previous studies have examined the effectiveness and correct methods of Mini-CEX, combined with student-standardized patient (SSP) evaluation, in rehabilitation medicine education. Therefore, this study aimed to explore whether combining Mini-CEX and SSP can improve resident physicians’ clinical and communication skills.
Methods: The sample comprised students who received standardized training for resident physicians from January 2022 to December 2023. Before the training began, the observation and control groups underwent Mini-CEX evaluation. During the training period, the observation group underwent Mini-CEX combined with SSP evaluation every two weeks, while the control group was not evaluated. Before leaving the department after the eighth week, the resident physicians’ learning outcomes were uniformly evaluated, including theoretical knowledge, Mini-CEX, clinical thinking ability, and specialized skill operation ability evaluation. A questionnaire survey method was adopted to collect students’ evaluations of teaching.
Results: The Mini-CEX combined with the SSP group showed a significant improvement in resident physicians’ comprehensive clinical ability (p<0.05). Compared with traditional Mini-CEX, resident physicians made greater progress in clinical thinking and patient communication skills (p<0.05). The survey results indicated that resident physicians have a high level of satisfaction with the evaluation of Mini-CEX combined with SSP.
Conclusion: Mini-CEX combined with SSP is an effective and reliable evaluation method for rehabilitation resident physician training, which fully emphasizes its advantages in improving students’ clinical abilities.
Enhancing Multi-View Deep Image Clustering via Contrastive Learning for Global and Local Consistency
Authors: Shi Fuhao , Lu Hu
Published: November 2024

Multi-view clustering (MVC) is a data clustering method with many applications, including but not limited to image and video analysis, text and language processing, bioinformatics, and signal processing. The objective of multi-view deep clustering is to enhance the efficacy of clustering algorithms by integrating data from disparate views. However, discrepancies and inconsistencies between different views frequently reduce the precision of the clustering outcomes. In the recent popular comparative learning, it has been observed that the processing of positive and negative samples does not consider the multi-view consistency information, ultimately resulting in a decline in clustering accuracy. In this paper, we put forth a global and local consistency-based contrast learning framework to enhance the efficacy of multi-view deep clustering. First, a global consistency constraint is designed to ensure that the global representations of different views can be aligned to capture the data's main features. Secondly, we introduce a local consistency mechanism, which aims to preserve the unique local information in each view and obtain efficient, positive samples to improve the complementarity and robustness of the inter-view representations through comparative learning. The experimental results demonstrate that the proposed method markedly enhances the clustering performance on several real benchmark datasets, mainly when dealing with multi-view data with incompleteness.
Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining
Authors: Godinez-Macias Karla P. , Chen Daisy , Wallis J. Lincoln , Siegel Miles G. , Adam Anna , Bopp Selina , Carolino Krypton , Coulson Lauren B. , Durst Greg , Thathy Vandana , Esherick Lisl , Farringer Madeline A. , Flannery Erika L. , Forte Barbara , Liu Tiqing , Magalhaes Luma Godoy , Gupta Anil K. , Istvan Eva S. , Jiang Tiantian , Kumpornsin Krittikorn , Lobb Karen , McLean Kyle , Moura Igor M. R. , Okombo John , Payne N. Connor , Plater Andrew , Rao Srinivasa P. S. , Siqueira-Neto Jair L. , Somsen Bente A. , Summers Robert L. , Zhang Rumin , Gilson Michael K. , Gamo Francisco-Javier , Campo Brice , Baragaña Beatriz , Duffy James , Gilbert Ian H. , Lukens Amanda K. , Dechering Koen J. , Niles Jacquin C. , McNamara Case W. , Cheng Xiu , Birkholtz Lyn-Marie , Bronkhorst Alfred W. , Fidock David A. , Wirth Dyann F. , Goldberg Daniel E. , Lee Marcus C.S. , Winzeler Elizabeth A.
Published: November 2024

The identification of novel drug targets for the purpose of designing small molecule inhibitors is key component to modern drug discovery. In malaria parasites, discoveries of antimalarial targets have primarily occurred retroactively by investigating the mode of action of compounds found through phenotypic screens. Although this method has yielded many promising candidates, it is time- and resource-consuming and misses targets not captured by existing antimalarial compound libraries and phenotypic assay conditions. Leveraging recent advances in protein structure prediction and data mining, we systematically assessed the Plasmodium falciparum genome for proteins amenable to target-based drug discovery, identifying 867 candidate targets with evidence of small molecule binding and blood stage essentiality. Of these, 540 proteins showed strong essentiality evidence and lack inhibitors that have progressed to clinical trials. Expert review and rubric-based scoring of this subset based on additional criteria such as selectivity, structural information, and assay developability yielded 67 high priority candidates. This study also provides a genome-wide data resource and implements a generalizable framework for systematically evaluating and prioritizing novel pathogenic disease targets.
Synergistic Improvement of Stone Matrix Asphalt Mixtures Incorporating Reclaimed Asphalt Aggregates and Warm Mix Additives Using Multivariate Analysis
Authors: N Jivitha , A Ramesh , V Venkat Ramayya , M Kumar
Published: November 2024

The demand for sustainable, eco-friendly and economically viable road construction methods has spurred researchers to explore the integration of Reclaimed Asphalt Pavement (RAP)-derived aggregates and warm mix additives into Stone Matrix Asphalt (SMA) mixtures. In pursuit of this goal, this study seeks to pinpoint the optimal material composition for SMA by incorporating RAP and warm mix additives. Diverse SMA mixes were prepared as per MS-2 manual series with PMB 70, 13.2 mm Nominal Maximum Aggregate Size, varying proportions of RAP (20–40%), warm mix additives (2–5%) and waste cooking oil (WCO) as rejuvenating agent. Laboratory tests viz. Saturates-Aromatics-Resins-Asphaltenes (SARA) Analysis, Marshall parameters, Indirect Tensile Strength, Moisture Susceptibility, Resilient Modulus and Rutting Resistance were performed. Grey relational analysis was employed to establish correlations between performance parameters and prioritize them accordingly. Heat maps were generated using the Python Jupiter platform for better visualization of results. The laboratory evaluations revealed that SMA mixtures formulated with 3% Sasobit in Polymer-Modified Bitumen (PMB) and 30% RAP along with 6% WCO exhibited exceptional performance across all test parameters. Grey relational grades provided coefficients for the test parameters, facilitating the ranking of potential mixtures based on overall performance and aiding in the selection of the most suitable mix designs. The results underscored the effectiveness of warm mix additives and the synergistic benefits of RAP in enhancing the performance properties of SMA mixtures. The current study supports up the idea of using WMA technology in combination with 6%WCO and 30% RAP in SMA mixtures produced with PMB. These findings offer valuable insights for the development and selection of SMA mixtures that promote enhanced efficacy and sustainable road construction practices.
The Efficacy and Safety of Early Treatment with Rituximab in Children with steroid-sensitive Nephrotic Syndrome: A Randomized Controlled Trial
Authors: Zhang Xiaoyue , Deng fang
Published: November 2024

Objective: To evaluate the efficacy and safety of early Rituximab (RTX) treatment in reducing relapses within two years for newly diagnosed steroid-sensitive nephrotic syndrome (SSNS).
Methods: A randomized controlled trial was conducted in the Anhui Children's Hospital from June 2021 to February 2022. This prospective study included 30 children diagnosed with initial SSNS who were randomly divided into RTX and steroid control groups. The RTX group received 375 mg/m2 RTX within one week, while the control group underwent standard treatment according to current evidence-based guidelines. Kaplan-Meier analysis was used to assess relapse-free survival rates and the incidence of frequent relapsing nephrotic syndrome/steroid-dependent nephrotic syndrome (FRNS/SDNS). Analysis of variance was employed to evaluate IL-8 levels before and after treatment.
Results: The two-year survival curves, with relapse as the endpoint event, showed significant differences between the RTX and steroid control groups (log-rank test c2=5.49, P<0.05). The two-year relapse-free survival rates were 57.14% and 21.42% for the RTX and control groups, respectively. In the RTX group, IL-18 decreased significantly from 55.90±12.36 pre-treatment to 24.98±1.96 one month post-treatment (P<0.05).
Conclusion: Early RTX treatment can improve relapse-free survival rates in pediatric SSNS patients. IL-18 levels decrease one month after RTX treatment. This therapy is relatively safe, and no severe adverse reactions were observed.
Development of Arduino-based Electronic Component Testing Device
Authors: Entienza Rexcel
Published: November 2024

As advancements in electronics continued, the limitations of traditional component testers became increasingly evident. Most available testers were designed to evaluate a single component type, resulting in a circuit testing process that was often cumbersome and time-consuming. This inefficiency posed challenges to both learning and innovation in educational and professional environments. To address the growing demand for more efficient and versatile testing tools, the development of a multi-component tester became crucial. The proposed project aimed to create an integrated electronic components tester capable of evaluating a wide range of components, including integrated circuits (ICs), resistors, transistors, and capacitors. This all-in-one device was designed to streamline the testing process, improving the user experience in electronics laboratories and supporting professionals in the fields of electronics repair and development.
Hepatoprotective Potential of Methanolic Extracts from Jatropha integerrima Leaves Against Carbon Tetrachloride (CCl4) Induced Rat Model.
Authors: Yousaf Faha , Iqbal Zafar
Published: November 2024

Introduction: Liver diseases are a significant public health issue globally, often caused by exposure to hepatotoxins like carbon tetrachloride (CCl4), which induces oxidative stress and liver injury. Natural compounds, particularly plant-based products, have gained attention for their hepatoprotective properties. Jatropha integerrima, a plant known for its antioxidant and anti-inflammatory effects, has not been extensively studied for its hepatoprotective effects against CCl4 induced liver damage.Methodology: Methanolic extracts of Jatropha integerrima leaves were prepared using a Soxhlet extraction method. Forty Sprague Dawley rats were divided into five groups: a control group, a CCl4-treated group, a silymarin-treated group (standard treatment), and two groups treated with low (200 mg/kg) and high (400 mg/kg) doses of the Jatropha extract. Liver function biomarkers, including bilirubin, alanine transaminase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP), were measured. Oxidative stress markers, total antioxidant capacity (TAC) and total oxidative stress (TOS), were also evaluated. Histopathological analysis of liver tissues was performed to assess structural damage.Results: CCl4-induced liver damage resulted in significant increases in serum liver enzymes and oxidative stress markers. Treatment with Jatropha integerrima extract significantly reduced ALT, AST, ALP, and bilirubin levels in a dose-dependent manner. The high-dose group showed reductions comparable to silymarin. TAC levels were significantly improved, while TOS levels were reduced. Histopathological analysis revealed that the high-dose Jatropha group showed near-complete restoration of liver architecture, with reduced necrosis and inflammation.Discussion: The hepatoprotective effects of Jatropha integerrima may be due to high concentrations of polyphenols and flavonoids available in this plant to counter act the free radicals and oxidative stress. These results confirm to other research on other species of Jatropha and increase the therapeutic value of Jatropha integerrima as a natural means to treating hepatotoxicity ailments.Conclusion: Methanolic extracts of Jatropha integerrima provide substantial hepatic protection against CCl4 induced liver injury in rats through marked improvement in liver function, reduction of oxidative stress and better maintenance of hepatic morphology. These findings indicated that Jatropha integerrima might provide a promising alternative for treating any kind of liver diseases and this study has to pave the way for further research in order to discover the full potential and efficacy of Jatropha integerrima in treating diseases of the liver.
Analysis of Gene Expression Linked to Efflux Pumps and Porins in Pseudomonas aeruginosa Isolates
Authors: Rahi Alya Amer
Published: November 2024

Background:
Efflux pumps (EPs) are essential in bacterial resistance, actively expelling antibiotics to reduce susceptibility. In Pseudomonas aeruginosa, they show a role in multi-drug resistance. Porin modifications, are serious for carbapenem uptake, and enhance resistance by restricting antibiotic entry.
Objective:
This study investigates the roles of efflux pumps and porins in antibiotic resistance, aiming to guide more effective treatment strategies for Pseudomonas aeruginosa infections.
Materials and Methods:
A total of 300 clinical specimens were collected from Hilla Teaching Hospitals between January and June 2024, comprising wounds (40%), burns (40%), blood (12%), and urine (8%). Bacteria were cultured, identified through Gram staining and biochemical tests, and confirmed as Pseudomonas aeruginosa (8.33%) via the Vitek-2 system. Antimicrobial susceptibility testing was conducted for 16 antibiotics. Efflux pump genes (adeB, adeJ) were detected using PCR, and their expression was quantified through RT-qPCR.
Results:
Pseudomonas aeruginosa isolates showed high resistance to β-lactams, carbapenems, and aminoglycosides, with colistin remaining effective. The adeB gene was present in all isolates, while adeJ was absent. Overexpression of OperD (80%) and adeB (44%) was observed, alongside complete downregulation of the CarO gene (100%).
Conclusion:
This study identified Pseudomonas aeruginosa in 8.33% of clinical specimens, revealing key resistance mechanisms, including OperD and adeB overexpression and CarO downregulation.
Introducing Cryptographic Behavioral Signatures for Ransomware Detection: A Novel Approach Using Hybrid Computational Profiling
Authors: Algarica Naomi , Winterburn Imogen , Penrose James , Greythorne Katrina
Published: November 2024

Emerging threats in cybersecurity necessitate innovative detection methodologies capable of addressing rapidly evolving attack mechanisms. Cryptographic Behavioral Signatures (CBS) were introduced as a dual-layered approach integrating cryptographic analysis with behavioral profiling to enhance the detection of malicious activities within digital systems. The framework achieved robust detection capabilities across diverse ransomware families through the systematic identification of cryptographic entropy anomalies and behavioral deviations from normal operational patterns. Experimental evaluations demonstrated high detection accuracy, with minimal false positive and false negative rates, even under conditions of significant noise and computational complexity. A modular architectural design enabled seamless integration into distributed environments, maintaining consistent performance while balancing computational efficiency and scalability. Unlike traditional signature-based or heuristic approaches, CBS achieved adaptability to previously unseen threats through intrinsic profiling mechanisms, reducing dependency on extensive labeled datasets. Quantitative analyses highlighted the framework’s resilience against adversarial evasion tactics, as well as its ability to detect zero-day attacks through entropy-based cryptographic markers. Comparative evaluations demonstrated its superiority over conventional methods, particularly in environments demanding precision and low latency. System resource utilization metrics further validated its feasibility for deployment in resource-constrained and large-scale infrastructures. Comprehensive testing across encryption depths and noise levels provided additional evidence of its operational reliability. The research demonstrated the potential for bridging theoretical advancements in profiling with practical applications in threat mitigation. By leveraging the unique behavioral and cryptographic markers of malware, the framework addressed critical gaps in the cybersecurity landscape while offering a scalable and adaptive solution to evolving challenges.
СОВРЕМЕННОЕ ЛАТЕНТНОЕ ВАРВАРСТВО: ПРОИСХОЖДЕНИЕ, СУЩНОСТЬ И НЕОПРЕДЕЛЕННОСТЬ
Authors: А.В. БУДАНОВ
Published: November 2024

Целью статьи является анализ происхождения и проявлений современного латентного варварства. Приведено общее определение этого типа варварства. Конкретизированы дефиниции варварство скрытое, варварство скрываемое. Рассмотрены современные предпосылки, причины и условия существования и развития латентного варварства. Специально проанализирована роль диалектики цивилизационных процессов и возможностей их реверсивной динамики в развитии современного латентного варварства. Противоречия между уровнем развития гуманистических начал современной цивилизации и нарастанием варварства как результата современного цивилизационного кризиса охарактеризованы в качестве базового условия существования и развития латентного варварства. Показана особая опасность этого типа варварства для современных цивилизационных процессов и его разрушительноe воздействиe на личность. Намечены некоторые пути дальнейшего исследования проблемы.

The aim of the article is the analysis of the origin and the manifestations of the modern latent barbarity. The common definition of that type of barbarity was given. The definitions as hidden barbarity, hides barbarity made more concrete. The modern prerequisites, reasons and conditions of appearance and development of the latent barbarity were analyzed. The role of the dialectics of the civilizational processes and the possibility of its reverse dynamics in the development of the modern latent barbarity were analyzed specially. The contradictions between the level of development of humanistic principles of the modern civilization and the increase of barbarity, which is the result of the modern civilizational crisis, were characterized as the basic condition of the appearance and the development of the latent barbarity. The particular danger of that type of barbarity for the modern civilizational processes and its destructive influence on the person are characterized. Some ways of the further investigation of the problem were outlined.
ЛАТЕНТНОЕ ВАРВАРСТВОУ ФУКИДИДА
Authors: И.Е. СУРИКОВ
Published: November 2024

В отличие от Геродота, у которого тема мир эллинства мир варварства проходит через весь труд, в сочинении Фукидида варвары появляются относительно редко. Конечно, нельзя сказать, что совсем не появляются: достаточно вспомнить душераздирающее описание резни наемникамифракийцами жителей беотийского Микалесса. Однако основной пафос Истории Фукидида в другом: показать, как многолетняя, кровопролитная, а главное междоусобная и братоубийственная война самих греков делает как бы варварами в худшем смысле слова, то есть манифестирует в них черты латентного варварства. Встатье указывается, что лексика, связанная с варварами и варварством, в труде Фукидида распределена неравномерно. Чаще всего она фиксируется в первой книге, которая наименее однородна по содержанию. В так называемой Археологии, в частности, имплицитно ставится вопрос о различиях между эллинами и варварами. Историк отмечает, что есть на окраинах Греции племена, которые хотя этнически и являются эллинами, но по реалиям жизни больше похожи на варваров (например, этолийцы). Но в дальнейшем по ходу повествования всё более нагромождается некая всеобщая варваризация в Элладе с соответствующей эскалацией жестокости. Данной тематике посвящены несколько эмоциональных, гневных пассажей Фукидида.

Unlike Herodotus, whose work is full with the world of Hellenism the world of Barbarism topic, in Thucydides treatise barbarians appear relatively seldom. Surely it is impossible to say that they never appear: it suffices to recollect the breathtaking description of the massacre made by Thracian soldiers in Mycalessus, Boeotia. However, the main pathetic of Thucydides Histories is another: to demonstrate how a long bloody war among Greeks makes them looking like barbarians in the worst meaning of the word, that is, manifests features of latent barbarity in them. The article points that vocabulary connected with barbarity and barbarians is distributed not in equal measure in different parts of Thucydides work. Most often it is used in Book One, which is the least homogeneous in its content. In socalled Archaeology, in particular, a question is implicitly posed on differences between Hellenes and barbarians. The historian notes that at the periphery of Greece there are tribes (for example, Aetolians), which, although Greek ethnically, are more similar to barbarians by features of their life. But further in the course of narration there appears the growth of a kind of general barbarization in Hellas, with corresponding escalation of cruelty. Several emotional, even angry passages are devoted by Thucydides to this theme.
ЛАТЕНТНОЕ ВАРВАРСТВО КАК МОТИВАНТИВАНДАЛЬСКОЙ РИТОРИКИВ СОЧИНЕНИЯХБЛОССИЯ ЭМИЛИЯ ДРАКОНЦИЯ
Authors: И.М. НИКОЛЬСКИЙ
Published: November 2024

В статье на примере творчества карфагенского поэта V в. Драконция рассматривается феномен латентного варварства как инструмента политической пропаганды в Поздней Античности. Основная идея состоит в том, что значительная часть его произведений, независимо от жанра и времени создания (среди них Искупление, Контроверсия о статуе храброго мужа, Трагедия Ореста и другие) содержат скрытую антивандальскую инвектику. Расшифровать ее оказывается возможным, обратив внимание на систему сквозных образов и терминов, выставляющих варваров в неприглядном свете.

The article deals with the problem of the latent barbarity as an instrument of political propaganda in Late Antiquity, by the case of Dracontius, a 5th century Carthaginian poet. The main idea is that most of his works, whatever their genre and time of creation (there are Satisfactio, Controversia de statua viri fortis, Orestis Tragoedia among them and others), contain implicit antiVandal invectics. It can be deciphered when drawing the attention on the system of crosscutting images and terms, showing the barbarians in an unflattering light.
БЛЕСК И НИЩЕТА КИРЕНЕИ: ЛАТЕНТНОЕ ВАРВАРСТВОВ «ЦИВИЛИЗОВАННЫХ» ОДЕЖДАХ
Authors: Л.Л. СЕЛИВАНОВА
Published: November 2024

В работе предпринята попытка взглянуть на события последнего десятилетия в одной из горячих точек планеты через прошлое в контексте проблематики цивилизация и варварство. Цель статьи выяснить, для чего использовалось, как проявлялось и к чему приводило латентное (скрываемое) варварство завоевателей в регионе Северной Африки в античную эпоху и в новейшее время. В связи с этим ставится задача: рассмотреть внутреннюю политику римлян в провинции Киренаика, колониальную компанию итальянских фашистов в Северной Африке и НАТОвскую интервенцию Ливии в 2011 г. Автор показывает, в какие разнообразные цивилизованные одеяния облачается латентное варварство ради достижения своих целей.

This article looks at recent developments in one of the most politically vulnerable regions of the world through its more distant past within the theoretical context of relationship between civilization and barbarism. The author demonstrates the similarity of purpose, attributes, and outcomes of the latent (crypto) barbarism of foreign invaders in northern Africa during the ancient and modern periods, by offering a diachronic comparison of Roman policy in the province of Cyrenaica, the colonial wars of Italian Fascism in northern Africa, and the military intervention of NATO in Libya in 2011. Putting such evidence together offers an ample illustration of how the latent barbarism has used the guise of promoting progress and civilization to pursue its own interests.
О локализации некоторых монетных дворов в Армении и Кавказской Албании (VIII ‒ начало XIV века)
Authors: А.В. Акопян
Published: November 2024

В статье обобщаются сведения о новых локализациях и чтениях названий монетных дворов, работавших на территории исторической Армении и Кавказской Албании с VIII в. до начала XIV века. Чтение монетного двора на омейядском дирхаме 89/708г. как Албанк и отнесение его к Кавказской Албании указывается как возможное, но требующее дополнительного подтверждения из других письменных источников, надежно соотносимых с этим регионом. Приводятся пять локализаций для монетного двора Арминиййа омейядского и аббасидского времени. Это Дамаск (монеты 78/69798г. возможно, в Дамаске были сделано только штемпели для этих монет), Двин (в 81256/700870 и 277332/890944 гг.), возможно, Амида (или где-то в области Алдзник, в 261277/874891 гг.), скорее всего, Бардаа (в 265277/878891 гг.) и, возможно, где-то в области Васпуракан (замок Даройнк или о. Ахтамар, в 355/966 г. более точная локализация затруднительна ввиду мобильности столицы Васпураканской Армении). Исправлено общепринятое, но неверное чтение монетного двора Мадин Бджунайс: его корректное чтение Мадин Бxунайс, а локализация в армянской области Апаhунес. Констатируется отсутствие уверенности в отождествлении раннемонгольского монетного двора Бб с топонимом Бавонк в области Арагацотн. Доказывается, что локализация хулагуидского монетного двора Пол-и рас ( Мост через Аракс ) должна связываться не с Нахичеваном, но с двумя крупнейшими инженерными сооружениями через эту реку Ходаферинскими мостами, интенсивно использовавшимися в указанное время.

The new localization and reading for mints located on the territory of historical Armenia and Caucasian Albania generalized and discussed in the article. The reading of the mint for the Umayyad dirham 89 AH/708 AD as Albanq and its identity with (Caucasian) Albania proposed to be possible, but requires confirmation in other written sources, reliably attributed to the this region. The five localizations of mint Arminiyya of Umayyad and Abbsid time are listed. They are Damascus (78 AH / 69798 AD possibly in Damascus only dies of this year were produced), Dvin (81256 AH / 700870 AD and 277332 AH / 890944 AD), perhaps Amida (or somewhere in Ajnik, in 261277 AD / 874891 AD), presumably Bardhaa (265277 AH / 878891 AD) and possibly somewhere in the region of Vaspurakan (castle of Daroink or island of Atamar, in 355 AH / 966 AD more precise localization of coinage in Vaspurakan Armenian impossible in view of the mobility of its capital). The longstanding erroneous reading of the mint Madin Bjunays was corrected the mintname should be read as Madin Bunays with localisation in the Armenian region of Apahunik (Apahunes). Still not a definitive the identification of the Mongol time mintplace Bb with the village Bawonk in the Aragacotn region of Armenia. The localization of lnid time mint Pol-i ras (Bridge over the Araxes) proved to be bonded not with Nakhjawn, but with the largest bridges on this river Khod fern bridges, heavily used at the specified time.
Северная граница Белозерского княжества по актам XV–XVI веков
Authors: А.Л. Грязнов
Published: November 2024

В статье анализируются сведения источников о политической и епархиальной принадлежности территорий и отдельных пунктов на севере Белозерья. Уточнение епархиальных границ и выяснение их изменений на протяжении XVIXVII вв. позволяют выявить следы колонизационных волн из Ростовской и Новгородской земель в древнерусский период и определить новгородско-белозерскую границу в XIIIXIV веках. Систематизация сведений об административной структуре Чарондской округи и о пересечении церковной юрисдикции на ее территории показывает, что положения Яжелбицкого договора об отказе новгородцев от приобретений на Белоозере были связаны с проникновением новгородских землевладельцев на Белоозеро, которое к середине XV в. стало вполне ощутимым. Источники дают возможность раскрыть механизм, форму и географию таких приобретений. Расположение административных и политических границ на севере Белозерья связано с историей освоения региона и формированием транспортных артерий еще в древнерусский период. Несмотря на относительную стабильность границ, наблюдаются их подвижки на локальном уровне, что было связано как с политической ситуацией, так и с успехами одной из сторон в хозяйственной сфере.

The article analyzes information about the political and diocesan affiliation of territories and individual points in the north of Belozere. Clarification of the diocesan borders and explanation of their changes during the 16th17th centuries reveal traces of colonization waves from the Rostov and Novgorod lands in the Old Russian period and determine the Novgorod-Belozersk border in the 13th14th centuries. The systematization of information about the administrative structure of the Charonda district and about the intersection of church jurisdiction in its territory shows that the provisions of the Yazhelbitsky agreement on the refusal of Novgorodians of acquisitions at Beloozero were related to the penetration of Novgorod landowners into Beloozero, which by the middle of the 15th century became quite tangible. Sources provide an opportunity to reveal the mechanism, form and geography of such acquisitions. The location of administrative and political borders in the north of Belozere is associated with the history of the development of the region and the formation of transport arteries in the Old Russian period. Despite the relative stability of the borders, they are moving at the local level, which was associated both with the political situation and with the successes of one of the parties in the economic sphere.
City-state in the modern world: Distinguishing features, advantages and problems
Authors: И.Ю. Окунев , Б.А. Барабаш
Published: November 2024

Статья посвящена феномену города-государства : соотношению города и государства, а также отличительным характеристикам города-государства с точки зрения современного подхода кего изучению. В статье произведена попытка провести классификацию современных городов-государств наряду с микрогосударствами, объединенными общим понятием малые политии , осуществлен анализ статусно-ролевых наборов, функциональных ниш и интересов трех типов малых политий: микрогосударства, города-государства изависимого города на примере Бутана, Сингапура и Гонконга

The paper is devoted to the phenomenon of a city-state: the correlation of the city and the state, as well as the distinguishing characteristics of the city-state from the point of view of the modern approach to its study. The paper attempts to classify modern city-states along with micro-states united by the general concept of small polities, analyzes the status-role sets, functional niches and interests of three types of small polities: microstates, city-states and dependent cities using the example of Bhutan, Singapore and Hong Kong.
Cвидетельства иностранцев о водных путях, которыми они впервые попали на Русь (XVI – начало XVII в.)
Authors: А.В. Постников
Published: November 2024

Статья посвящена анализу сообщений иностранных путешественников XVI начала XVII в., прибывавших на Русь водными путями. Записки этих путешественников, а также составленные ими карты являются ценным источником не только по истории географических знаний и картографии, но и по истории освоения внутренних водных путей Русского государства важнейших транспортных артерий, соединявших бассейны Белого и Балтийского морей с акваторией Каспийского моря. Встатье рассматриваются данные о путешествиях в Московию в XVI в. представителей английской Московской компании Ричарда Ченслера, братьев Боро, Томаса Соутэма, Джона Спарка, Этнони Дженкинсона, которые внесли большой вклад в географическое описание и картографирование Восточной Европы. Исследуются свидетельства о деятельности голландских купцов и мореходов, путешествовавших на Русь в XVIв. Симона ван Салингена и Корнелия де Мейера, а также карта Балтийского моря Корнелиуса Дутса 1589 года. Подробно анализируется географическая информация, содержащаяся в Записках о Московии Генриха фон Штадена (вторая половина XVI века). Чертеж украинским и черкасским городам от Москвы до Крыма (первая половина XVII в.), на котором представлена гидрография южной части Русского государства, рассматривается в контексте работы по картографированию русских земель, проводившейся на Руси во второй половине XVI начале XVII века.

The paper is devoted to the analysis of reports of foreign travelers from the 16th to the beginning of the 17th century, who arrived in Russia by water. The notes of these travelers, as well as the maps compiled by them, are a valuable source not only for the history of geographical knowledge and cartography, but also for the history of the development of the inland waterways of the Russian state the most important transport arteries connecting the basins of the White and Baltic Seas with the Caspian Sea. The paper discusses data on travels to Muscovy in the 16th century by representatives of the English Muscovy Company Richard Chansellor, the Borough brothers, Thomas Southam, John Sparke, Anthony Jenkinson who made a great contribution to the geographical description and mapping of Eastern Europe. The evidence of the activities of Dutch merchants and sailors traveling to Russia in the 16th century Simon von Saling and Cornelius de Meyer is investigated, as well as a 1589 map of the Baltic Sea by Cornelius Duts. The geographical information contained in the Notes on Muscovy by Heinrich von Staden (second half of the 16th century) is analyzed in detail. A drawing to Ukrainian and Cherkassky cities from Moscow to Crimea (the first half of the 17th century), which shows the hydrography of the southern part of the Russian state, is considered in the context of the work on mapping of the Russian lands carried out in Russia from the second half of the 16th to the beginning of the 17th century.
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Authors: Soran Mamand Abdullah  , Ebraheem Khaleel Fethullah
Published: November 2024

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Authors: Surwd Fuwad Mohammed Sarraj  , Amanj Ghazi Shaker Agha
Published: November 2024

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Authors: Chaware Neamat Saleh  , Renas Khalis Nader
Published: November 2024

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Authors: Srusht Jawhar Hawez
Published: November 2024

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Clinical Courses and Outcomes of COVID-19 in Patients Undergoing Chronic Hemodialysis and Peritoneal Dialysis in Northeast Thailand
Authors: Waramit Sirayut
Published: November 2024

End-stage renal disease (ESRD) is one of the risk factors for infection, morbidity, and mortality in SARS-CoV-2. This study was aimed to evaluate the prevalence, clinical courses, and outcomes of patients undergoing chronic hemodialysis (HD) and peritoneal dialysis (PD). Materials and Methods: This was a retrospective study of ESRD patients admitted to Sakon Nakhon Hospital between October 2020 and September 2022. Data were analyzed for the incidence, demographic characteristics, clinical outcomes, laboratory tests, and mortality rates of the HD and PD patients who tested positive for COVID-19. Results: There were 73 ESRD patients (mean age 58.7 years, male 50.7%), who were positive for COVID-19 infection, of which 76.7% were on HD and 23.3% in the PD program. Hypertension (89.0%) and diabetes (54.8%) were more frequent comorbid conditions. Compared to the route of transmission, the HD group was more from hospital transmission (P = 0.03), while home transmission was more common in the PD group (P = 0.003). Serum potassium (P = 0.008) and albumin (P = 0.0005) were more in HD than PD, but bicarbonate (P = 0.01) was less. There was no significant in severity (P = 0.88) and mortality (P = 0.55) between both groups. Seven (9.6%) patients died. Risk factors compared between survivor and non-survivor groups significantly were serum albumin <3.5 g/dL (P = 0.008) and vaccination <2 shots (P = 0.04). Risk factor associated mortality in COVID-19 patients ongoing dialysis was low serum albumin <3.5 g/dL ([OR] 11.22, 95%, [CI] 1.27–98.91, P = 0.029). Conclusion: ESRD patients undergoing HD or PD were susceptible to COVID-19 infection. A comparison between the standard deviation and PD was found, but there was no significant difference in the clinical course and outcome of treatment in both groups.