bluuebunny/crossref_metadata_2025 huggingface dataset:
Multiplicative design and technological solutions in development and industrial application of pulse-cyclic electrochemical method
Authors: Usov S.V. , Sukhochev G.A. , Zhdanov A.V. , Mitrofanov A.N. , Tochilin I.P.
Published: May 2024

The article presents multiplicative design and technological directions in the development and application of the pulse-cyclic method of volumetric shaping. Previously published scientific and technical publications dealt with the consideration of technological and metal-physical aspects of pulse-cyclic shaping. At the same time, the achieved indicators of these parameters are largely determined by the implemented design and technological solutions of the equipment used. The applied modular principle of construction of metalworking equipment. Allows for the construction of multiplicative design and technological solutions in the development of equipment for the industrial application of the electrochemical pulse-cyclic method. On the basis of the proposed approach, electrochemical copy-piercing machines of the EHP-1 model were created and introduced into industrial production. The presented multiplicative solutions in this article show how it is possible to create high-tech domestic machine-tool equipment. Ensuring the scientific and technical competitiveness of the developed pulse-cyclic electrochemical processing allows solving complex industrial problems to provide electrochemical equipment with the required level of accuracy and performance.
Electrolic plasma polishing of complex parts in magnetic field
Authors: Krioni N.K. , Mingajev A.D. , Kutluev V.M. , Mingajeva A.A.
Published: May 2024

The article discusses a new technology of electrolyte-plasma polishing (EPP) of turbomachine parts with the imposition of an external magnetic field, which improves the quality of the surface layer. The results of experimental studies of the effect of electrolytic-plasma polishing of blades made of titanium alloy VT6 with the imposition of an external magnetic field are presented, indicating the prospects of using the proposed EPP method for processing parts of complex configuration, as well as the possibility of increasing the stability of the EPP process with the introduction of a magnetic field as an additional technological factor.
Pesquisa Sobre os Fatores Limitantes da Gestão do Capital de Giro em Micro e Pequenas Empresas na Cidade de Arinos-MG
Authors: Oliveira Paloma Lopes , Alves Raquel Aparecida , Campos Gevair
Published: May 2024

O estudo em questão discute os fatores limitantes da gestão do capital de giro em MPEs em uma pequena cidade do Noroeste do estado de Minas Gerais ao propor o seguinte questionamento: Quais são os fatores limitantes da gestão de capital de giro nas micro e pequenas empresas no município de Arinos-MG? Para responder à questão levantada, os objetivos geral e específicos foram compreender os fatores limitantes da gestão de capital de giro nas micro e pequenas empresas, levantar o perfil dos gestores, descrever os instrumentos, as ferramentas e metodologias usadas para gerir o capital de giro e investigar as fontes de capital de giro e como ocorre o fluxo desses recursos. De natureza quantitativa e descritiva, a pesquisa se serviu de um formulário de pesquisa da plataforma Google Forms para questionar, via WhatsApp, vinte e nove gestores de MPEs do ramo de comércio varejista de produtos em geral que possuem empresas com mais de três anos, vendem a prazo e são classificadas como micro e pequenas empresas de acordo com a Lei n.º 123/2006. Os resultados apontam que os fatores que contribuem e os problemas enfrentados giram em torno do pouco prazo para pagamento de fornecedores, pagamento de juros e impostos além da necessidade de empréstimo e burocracia para captar recursos e não ter disponibilidade dos documentos exigidos pela instituição financeira; e as principais conclusões giram em torno da necessidade do gestor em continuar buscando aprendizado e aperfeiçoar a prática para minimizar os impactos da escassez de capital no curto prazo.
Hip sonography in Switzerland
Authors: Dubs Beat
Published: May 2024

The diagnosis of hip dysplasia has developed very differently in different countries over the last few decades. The development and current situation in Switzerland is described in this paper. In the meantime, early diagnosis by means of Graf hip sonography, corresponding to screening, has been established, although it varies from region to region. The training system for examiners is also clearly regulated. The massive reduction in costly treatments and operations documents the success of the efforts made in Switzerland.
How did the COVID-19 pandemic affect Corporate Cash Holdings Determinants? An Applied Study on Saudi Arabia Firms
Authors: Moez Dabboussi , Abdulrahman Badreldin Mohamed Ahmed
Published: May 2024

The COVID-19 pandemic has introduced substantial uncertainty and economic disruptions, prompting numerous firms to increase their cash reserves as a significant advantage to enable effective management of exogenous shocks. Using a sample of 120 non-financial firms listed on the Saudi Stock Exchange between 2012 and 2022, we examine the determinants of cash holdings. By dividing the sample into two sub-periods: pre-Covid and under Covid and applying the panel data approach, the results show a significant difference between the determinants of cash holdings of the two groups of firms. During the COVID-19 pandemic, cash holding has increased with firm size, cash flow, Cost of Capital, and net working capital, while it has decreased with dividend payment, and return on invested capital. The research provides support for the pecking order theory, indicating that Saudi firms have maintained relatively stable cash management policies and remained unaffected throughout the pandemic. This study sheds light on the supportive role of the Saudi government in assisting firms facing liquidity challenges, offering a comprehensive understanding of the subject. Furthermore, it contributes to the existing literature on corporate finance by exploring new factors that drive cash management decisions.
Adapting To Change: A Study Of Post-Pandemic Millennial Housing Preferences
Authors: Bedi Abdullah , Aswin Rahadi Raden
Published: May 2024

The COVID-19 pandemic has fundamentally altered societal dynamics, particularly in the realm of residential preferences. This thesis investigates the shifting trends in post-pandemic housing preferences and their impact on residential decision-making. Key factors such as size, layout, amenities, location, outdoor spaces, and technological advancements are scrutinized to comprehend the shifting landscape of residential choices. The study reveals an increased emphasis on home office spaces and adaptable layouts as a response to the pandemic's transformative influence. It also highlights a growing inclination towards outdoor spaces like gardens and multi-function rooms due to the increasing trend of working at home during and after pandemic. Additionally, changing priorities in location selection and the rising importance of health-related aspects in home design are explored. Employing qualitative methods, the research conducts semi-structured interviews with eleven (11) diverse respondents to gain insights into post-COVID-19 house preferences and decision-making processes. The findings provide valuable guidance for real estate professionals, urban planners, and architects, aiding them in adjusting to the evolving needs and preferences of residents. Beyond academic realms, the study carries practical implications, contributing to the creation of innovative housing solutions aligned with changing preferences and responsive to post-pandemic societal demands. Ultimately, it seeks to inform policymakers and stakeholders, facilitating the development of sustainable residential environments that effectively address the evolving needs of individuals and communities in the aftermath of the COVID-19 pandemic.
Deciding the Best Location for RM Bunut Sari to Open A New Branch in Greater Bandung
Authors: Prawira Ichsan Ramadhan , Putro Utomo Sarjono
Published: May 2024

This research aims to support the Sundanese restaurant RM Bunut Sari in determining the optimal location for opening a new branch in the Greater Bandung area of West Java. Environmental analysis is conducted by assessing the internal capabilities of RM Bunut Sari and examining external market conditions in Bandung City, Bandung Regency, and West Bandung Regency. Analytical Hierarchy Process (AHP) modeling is then utilized to evaluate which alternative location offers the greatest strategic advantages. Based on comparisons across decision criteria such as parking facilities, building size, visibility, distance from competitors, and property prices, Bandung Regency emerges as the recommended location. An implementation plan details the necessary launch activities spanning site selection, renovation, licensing and permissions, staffing, promotions, and eventual restaurant opening. The recommendations highlight leveraging RM Bunut Sari’s existing strengths in taste quality and service experience while closely monitoring operational and marketing outcomes from the new branch. Thus the analytical approach delivers an optimized location choice for RM Bunut Sari’s expansion, guided by environmental analysis and multi-criteria decision making.
The Influence of Net Profit Margin, Return on Asset, Current Ratio, Price Earning Ratio, Solvency Ratio on Market Price
Authors: Mashoeda Ivena
Published: May 2024

This study aims to analyze the influence of Profit Margin, Return on Assets, Current Ratio, Solvency Ratio on Market Price. Information about company share prices is related to these 5 variables. The data used in this research is the Consumer Good Industry Company (CGIC) which has complete data related to these variables so that the sample obtained is 13 companies in 2019-2022. The data analysis technique used in this research is the selection of a panel data regression model with the Chow test, Hausman test, large range multiplier (LM) test, and parameter significance test. The test results can be concluded that Net Profit Margin (NPM) has a significant effect on Market Price (MP) while Return on Assets (ROA), Current Ratio (CR), Price Earning Ratio (PER), Solvency Ratio (SR) do not have a significant effect on Market Price (MP).
ASUHAN KEBIDANAN PADA IBU BERSALIN NY S DENGAN DIDAMPINGI SUAMI GUNA PENGURANGAN RASA CEMAS MENGHADAPI PROSES PERSALINAN DI PUSKESMAS TANJUNG BALAI KARIMUN
Authors: Dwi Handayani Pratiwi , Aryaneta Yenni , Aidina Dyka
Published: May 2024

One of the hardest experiences for a mother is childbirth, because giving birth is one of the stakes for the life and death of a mother. Husband support during childbirth is a source of strength for mothers that cannot be provided by health workers. Objective To provide comprehensive and continuous midwifery care for mothers giving birth, with management of midwifery care in accordance with midwifery service standards. The midwifery care that was implemented was Midwifery Care for Mrs. S in Birth Accompanied by Her Husband to Reduce Anxiety in Facing the Childbirth Process. The practice report preparation method is descriptive research with the case study method conducted at the Tanjung Balai Karimun Health Center in March 2023. The subjects used in the case study with midwifery care management is Mrs. S. Results and Conclusions Evaluation of the care provided related to Midwifery Care for Mothers in Birth Mrs. S Accompanied by Her Husband to Reduce Anxiety Facing the Childbirth Process there is a reduction in the anxiety that mothers feel
A new fossil Malthodes (Coleoptera: Cantharidae) from the Baltic amber Lagerstätte

Authors: Parisi Francesco , Fanti Fabrizio
Published: May 2024

A new species of soldier beetle (family Cantharidae) from Eocene Baltic amber: Malthodes (s. str.) vallombrosa sp. nov., is described, diagnosed and illustrated. The morphological affinities with the most similar species are discussed. The Eocene Baltic amber was very rich in species of the genus Malthodes. The evolution of these insects probably began after or near the mass extinction that occurred 66 Ma.
DTI Measurements for Huntington Disease Using Mricloud
Authors: Arslan Ayla , Nisari Mehtap , Güler Emel , Bağcı Uzun Gökçe , Gültekin Murat , Dönmez Halil , Bağcı Keziban , Acer Niyazi
Published: May 2024

Aim: Neurodegenerative diseases are important health problems that affect many people. In this study, it was aimed to examine the brain regions of Huntington's patients by performing brain parcellation.
Material and Method: 8 controls and 8 Huntington's patients participated in the study. We measured four Diffusion Tensor Imaging metrics which were axial diffusivity, mean diffusivity, radial diffusivity and fractional anisotropy performing brain parcellation over Diffusion Tensor Imaging for control and patient groups. We used a full automated data-driven approach to study the whole brain, divided in regions of interest using mricloud.
Results: When the huntington disease group compared to control group, We found that mean diffusivity and axial diffusivity increased frontal, parietal, temporal, occipital, corpus callosum, white matter, limbic and subcortical structures, and radial diffusivity increased corpus callosum, capsula interna (p
TURNOVER INTENTION PERAWAT DI RUMAH SAKIT
Authors: Sabatini Monika Steffi Novia , Dwiantoro Luky , Dewi Nur Setiawati
Published: May 2024

Turnover intention adalah karyawan mempunyai niat untuk meninggalkan pekerjaannya yang sekarang dan mencari pekerjaan yang baru dalam rentang waktu tertentu.  Angka kejadian turnover perawat di rumah sakit yaitu jumlah perawat yang keluar pada tahun 2018 adalah  12,7% dan pada tahun 2019 perawat yang keluar adalah 12,4%. Identifikasi turnover intention penting dilakukan untuk meningkatkan retensi perawat di rumah sakit. Penelitian ini bertujuan untuk mengidentifikasi turnover intention di rumah sakit.   Metode penelitian yang digunakan adalah deskriptif kuantitatif. Sampel penelitian sebanyak 86 perawat yang dipilih secara purposive. Pengumpulan data menggunakan kuesioner yang terdiri dari 15 pertanyaan yang dibagikan kepada 86 perawat di rumah sakit yang sebelumnya telah dilakukan uji validitas dengan hasil t-hitung item 15 pertanyaan kuesioner variabel turnover intention lebih besar dari t-tabel (1,6632) maka pernyataan dinyatakan valid dan dapat digunakan dalam penelitian.  Hasil penelitian menunjukkan bahwa 84 perawat (97,67%)  berada pada kategori “sedang” sedangkan sisanya yaitu 2 perawat (2,33%) berada pada kategori “tinggi”. Hasil penelitian juga menunjukkan bahwa perawat ada kemungkinan untuk keluar dari rumah sakit dijabarkan dengan pertanyaan dalam kuesioner yaitudari rumah sakit lain. Penelitian yang dilakukan pada perawat di rumah sakit terhadap turnover intention memberikan kesimpulan bahwa ada kecenderungan perawat di rumah sakit melakukan turnover intention.
FAKTOR YANG BERHUBUNGAN DENGAN BERSIHAN JALAN NAPAS PADA PASIEN DENGAN GENERAL ANASTESI DI RUANG RECOVERY
Authors: Kristyanta Hery , Widyaningsih Widyaningsih , Mandaty Fhandy Aldy
Published: May 2024

General anesthesia (GA) is an agent used to relieve pain during surgery. Some patients after receiving general anesthesia experience ineffective airway clearance. Ineffective airway clearance in patients under general anesthesia is related to the patient's internal condition before surgery. The purpose of this study is to determine the relationship between smoking, alcohol consumption, congenital lung disease, and age with ineffective airway clearance in patients with GA in the recovery room. This study used a cross-sectional design. The number of samples used was 52 patients using purposive sampling. The instrument used is an observation sheet to identify factors of congenital lung disease, smoking, alcohol consumption, and age. Data analysis using chi-square. The results showed that there was a relationship between congenital lung disease, smoking, alcohol consumption, and age with ineffective airway clearance in patients with general anesthesia in the recovery room, respectively p=0.002, p=0.001, p=0.011, p=0.007. The factors associated with ineffective airway clearance in postoperative patients under general anesthesia include congenital lung disease, smoking, alcohol consumption, and age.
Passando a boiada: efeitos da suspensão da inspeção de exportações de produtos de madeira nativa
Authors: Araújo Cláudio , Féres José Gustavo
Published: May 2024

Em fevereiro de 2020, o Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis (Ibama) revogou a necessidade de autorização explícita das exportações de produtos de madeira nativa. Com isso, extinguia-se a necessidade de inspeções físicas das cargas exportadas. Tal medida gerou preocupações em relação a um potencial aumento no envio de madeira ilegal para o exterior. Este artigo procura fazer uma avaliação do impacto da suspensão das inspeções durante o período em que a medida esteve vigente. A análise identifica um aumento do registro de áreas de cortes seletivos desornados na Amazônia, prática tipicamente observada em áreas de extração ilegal de madeira, além de um aumento no volume de exportações que não parece ser explicado por variações de preços de mercado. Por fim, o texto reforça a necessidade de aperfeiçoar o rastreamento da cadeia de produção do setor madeireiro. Essa medida é fundamental para a modernização do setor, garantindo a produção sustentável e o uso eficiente dos recursos naturais, conforme preconizado pela agenda dos Objetivos de Desenvolvimento Sustentável (ODS).
Empirical Assessment of Maize Price Dynamics and Market Integration in Selected Regional Markets of Benue State, Nigeria.
Authors: Temitope Adefunsho Olatoye, , Okikioluwa Aderinsoluwa Dotun-Odumade, , Julius Olabode Elega,
Published: May 2024

This study investigated how maize prices move in selected regional markets in Benue State, Nigeria. The researchers looked at monthly maize price data from January 2008 to December 2018 to determine if the price series in these different markets were connected. Specific tests were used to determine if the prices influenced each other over time (market integration) and, if so, which market (rural or urban) tended to lead the price changes in the state. The result revealed that maize prices eventually stabilized over time (became stationary) and that rural and urban markets were indeed connected. There was also evidence of some level of market integration in the short term. Interestingly, the price changes in one market didn't always directly cause changes in the other market. In some cases, price changes seemed to flow in both directions. Based on these results, this study therefore recommends that the all stakeholders provide information centers and use media channels to improve communication between maize producers and consumers in the state; as this would allow actors to make more informed decisions about maize marketing.
Properties of the Line-of-sight Velocity Field in the Hot and X-Ray-emitting Circumgalactic Medium of Nearby Simulated Disk Galaxies
Authors: ZuHone John A. , Schellenberger Gerrit , Ogorzałek Anna , Oppenheimer Benjamin D. , Stern Jonathan , Bogdán Ákos , Truong Nhut , Markevitch Maxim , Pillepich Annalisa , Nelson Dylan , Burchett Joseph N. , Khabibullin Ildar , Kilbourne Caroline A. , Kraft Ralph P. , Nulsen Paul E. J. , Veilleux Sylvain , Vogelsberger Mark , Wang Q. Daniel , Zhuravleva Irina
Published: May 2024

The hot, X-ray-emitting phase of the circumgalactic medium of massive galaxies is believed to be the reservoir of baryons from which gas flows onto the central galaxy and into which feedback from active galactic nuclei and stars inject mass, momentum, energy, and metals. These effects shape the velocity fields of the hot gas, which can be observed via the Doppler shifting and broadening of emission lines by X-ray integral field units. In this work, we analyze the gas kinematics of the hot circumgalactic medium of Milky Way–mass disk galaxies from the TNG50 simulation with synthetic observations to determine how future instruments can probe this velocity structure. We find that the hot phase is often characterized by outflows from the disk driven by feedback processes, radial inflows near the galactic plane, and rotation, although in some systems the velocity field is more disorganized and turbulent. With a spectral resolution of ∼1 eV, fast and hot outflows (∼200–500 km s−1) can be measured, depending on the orientation of the galaxy on the sky. The rotation velocity of the hot phase (∼100–200 km s−1) can be measured using line shifts in edge-on galaxies, and is slower than that of colder gas phases but similar to stellar rotation velocities. By contrast, the slow inflows (∼50–100 km s−1) are difficult to measure in projection with these other components, but may be detected in multicomponent spectral fits. We find that the velocity measured is sensitive to which emission lines are used. Measuring these flows will constrain theories of how the gas in these galaxies evolves.
Probing Depth Variations of Solar Inertial Modes through Normal Mode Coupling
Authors: Mandal Krishnendu , Hanasoge Shravan M.
Published: May 2024

Recently discovered inertial waves, observed on the solar surface, likely extend to the deeper layers of the Sun. Utilizing helioseismic techniques, we explore these motions, allowing us to discern inertial mode eigenfunctions in both radial and latitudinal orientations. We analyze 8 yr of space-based observations (2010–2017) taken by the Helioseismic and Magnetic Imager on board the Solar Dynamic Observatory using normal mode coupling. Couplings between the same and different-degree acoustic modes and different frequency bins are measured in order to capture the various length scales of the inertial modes. We detect inertial modes at high latitude with azimuthal order t = 1 and frequency ∼ −80 nHz, measured in a corotating frame with a rotation frequency of 453.1 nHz. This mode is present in the entire convection zone. The presence of Rossby modes may be seen down to a depth of ∼0.83R
⊙, and the Rossby signal is indistinguishable from noise below that depth for high azimuthal order. We find that the amplitudes of these modes increase with depth down to around 0.92R
⊙ and decrease below that depth. We find that the latitudinal eigenfunctions of Rossby modes deviate from sectoral spherical harmonics if we use a similar approach as adopted in earlier studies. We find that spatial leakage and even pure noise in the measurements of nonsectoral components can also explain the abovementioned characteristics of the latitudinal eigenfunctions. This realization underscores the necessity for careful interpretation when considering the latitudinal eigenfunctions of Rossby modes. Exploring the depth-dependent characteristics of these modes will enable us to capture interior dynamics distinctly, separate from p-mode seismology.
The Effect of Starspots on Spectroscopic Age and Mass Estimates of Nonaccreting T Tauri Stars in the Taurus–Auriga Star-forming Region
Authors: Pérez Paolino Facundo , Bary Jeffrey S. , Hillenbrand Lynne A. , Markham Madison
Published: May 2024

Accurate age and mass determinations for young pre-main-sequence stars are made challenging by the presence of large-scale starspots. We present results from a near-infrared spectroscopic survey of 10 T-Tauri Stars in Taurus-Auriga that characterize spot-filling factors and temperatures, the resulting effects on temperature and luminosity determinations, and the consequences for inferred stellar masses and ages. We constructed composite models of spotted stars by combining BTSettl-CIFIST synthetic spectra of atmospheres to represent the spots and the photosphere along with continuum emission from a warm inner disk. Using a Markov Chain Monte Carlo algorithm, we find the best-fit spot and photospheric temperatures, spot-filling factors, as well as disk-filling factors. This methodology allowed us to reproduce the 0.75–2.40 μm stellar spectra and molecular feature strengths for all of our targets, disentangling the complicated multicomponent emission. For a subset of stars with multiepoch observations spanning an entire stellar rotation, we correlate the spectral variability and changes in the filling factors with rotational periods observed in K2 and AAVSO photometry. Combining spot-corrected effective temperatures and Gaia distances, we calculate luminosities and use the Stellar Parameters of Tracks with Starspots models to infer spot-corrected masses and ages for our sample of stars. Our method of accounting for spots results in an average increase of 60% in mass and a doubling in age with respect to traditional methods using optical spectra that do not account for the effect of spots.
Gaia23bab: A New EXor
Authors: Giannini T. , Schisano E. , Nisini B. , Ábrahám P. , Antoniucci S. , Biazzo K. , Cruz-Sáenz de Miera F. , Fiorellino E. , Gangi M. , Kóspál A. , Kuhn M. , Marini E. , Nagy Z. , Paris D.
Published: May 2024

On 2023 March 6, the Gaia telescope alerted a 2 mag burst from Gaia23bab, a young stellar object in the Galactic plane. We observed Gaia23bab with the Large Binocular Telescope obtaining optical and near-infrared spectra close in time to the peak of the burst, and collected all public multiband photometry to reconstruct the historical light curve. The latter shows three bursts in 10 years (2013, 2017, and 2023), whose duration and amplitude are typical of EXor variables. We estimate that, due to the bursts, the mass accumulated on the star is about twice greater than if the source had remained quiescent for the same period of time. Photometric analysis indicates that Gaia23bab is a class II source with age ≲1 Myr, spectral type G3−K0, stellar luminosity ∼4.0 L
⊙, and mass ∼1.6 M
⊙. The optical/near-infrared spectrum is rich in emission lines. From the analysis of these lines we measured an accretion luminosity and mass accretion rate (L
acc
burst ∼ 3.7 L
⊙,

M

̇

acc

burst ∼ 2.0 × 10−7
M
⊙ yr−1) consistent with those of EXors. More generally, we derived the relationships between accretion and stellar parameters in a sample of EXors. We find that, when in burst, the accretion parameters become almost independent of the stellar parameters and that EXors, even in quiescence, are more efficient than classical T Tauri stars in assembling mass.
Anxiety in the emergency medical practice – its psychiatric and somatic origin, comorbidities, behavior and treatment
Authors: Sarakostova Silvia , Pantileeva Diyana , Dilkov Dancho , Semerdzhieva Niya , Chaneva Mariya , Ivanova Stefka , Atanasova Ventseslava , Atanasov Petar , Rangelova Diana
Published: May 2024

Anxiety conditions and disorders are common in the general population, and patients suffering from them often seek the services of emergency departments. Anxiety is a psychopathological symptom that accompanies not only psychiatric conditions, but a wide range of somatic diseases, and a combination of both. The biochemical and pathophysiological mechanisms of psychosomatic interrelationship and comorbidity are complex and multi-layered. Thus, diagnosing the root cause of anxiety is a clinical challenge. Early, and on time, recognition of an anxiety disorder helps to avoid unnecessary investigations, ensures correct treatment and saves hospital resources. Careful use of medications, psychoeducation and referral to a specialist improves patient outcome with this potentially debilitating disease.

In this article, the authors aim to present in a synthesized form the main epidemiological data on the prevalence of anxiety symptoms and disorders, anatomical localization and biochemical mechanisms and relationships in the pathogenesis of anxiety symptoms, as well as to derive the main guidelines for recognizing and differentiating clinicopathological constellations in somatic conditions in emergency medical practice.

Materials and methods. Existing published studies from an international database, related to the subject of the article, have been thoroughly studied.

Results. Anxiety symptoms, in particular panic attacks and disorders, are widespread in primary care and occupy a significant part of the work process, especially at times of peak loads, natural disasters and situations of mass traumatism.

Conclusions. Timely training and good preparation for recognition and adequate assessment of anxiety conditions in primary and emergency medical care significantly shorten the therapeutic route of patients. They receive competent help on time, and the cost of their treatment is significantly reduced.

Discussion. Modern medical science, including psychiatric, offers advanced drug and non-drug methods for the treatment and prevention of anxiety conditions and disorders.
Machine Teaching Allows for Rapid Development of Automated Systems for Retinal Lesion Detection From Small Image Datasets
Authors: Drakopoulos Michael , Hooshmand Donna , Machlab Laura A. , Bryar Paul J. , Hammond Kristian J. , Mirza Rukhsana G.
Published: May 2024

Machine teaching, a machine learning subfield, may allow for rapid development of artificial intelligence systems able to automatically identify emerging ocular biomarkers from small imaging datasets. We sought to use machine teaching to automatically identify retinal ischemic perivascular lesions (RIPLs) and subretinal drusenoid deposits (SDDs), two emerging ocular biomarkers of cardiovascular disease. IRB approval was obtained. Four small datasets of SD-OCT B-scans were used to train and test two distinct automated systems, one identifying RIPLs and the other identifying SDDs. An open-source interactive machine-learning software program, RootPainter, was used to perform annotation and training simultaneously over a 6-hour period. For SDDs at the B-scan level, test-set accuracy = 92%, sensitivity = 100%, specificity = 88%, positive predictive value (PPV) = 82%, and negative predictive value (NPV) = 100%. For RIPLs at the B-scan level, test-set accuracy = 90%, sensitivity = 60%, specificity = 93%, PPV = 50%, and NPV = 95%. Machine teaching demonstrates promise within ophthalmic imaging to rapidly allow for automated identification of novel biomarkers from small image datasets.

[
Ophthalmic Surg Lasers Imaging Retina
2024;55:475–478.]
Breadmaking and protein characteristics of wheat (Triticum aestivum L.) genotypes tolerant against drought and heat in Algeria
Authors: Mahroug Hamida , Mouellef Adra , Bourekoua Hayat , Djeghim Fairouz , Chenchouni Haroun , Benbelkacem Abdelkader , El Okki Mohamed Hadef , Fetouhi Awatif , Silini Nedjla , de la Barca Ana María Calderón
Published: May 2024

The primary staple of the Algerian population is wheat, and due to climate change, it is necessary to look for wheat genotypes with a high yield, drought and heat tolerance, and disease resistance, in addition to high quality for bread-making and other foodstuffs. Our objective of this study was to investigate 17 genotypes of Triticum aestivum L., including 10 traditionally cultivated, 2 recently introduced, and 5 currently in development, with the goal of identifying those exhibiting high-quality attributes for breadmaking and superior technological properties, while maintaining low levels of immunoreactive gluten. We conducted analyses on chemical composition, immunoreactive gluten content, as well as the secondary structure of proteins and the conformation of starch in flours obtained from different wheat bread genotypes grown in similar watering and other conditions. Additionally, the rheological characteristics of the dough were measured using an alveograph and rheoviscosimeter. We also explored the physical properties and technological attributes relevant to the bread-making process. The major results indicated low heterogeneity among genotypes concerning immunoreactivity. The characteristics of 17 Triticum aestivum L. genotypes form four groups included: Group A: Traditional, recently, or not yet cultivated in Algeria, with the highest β-sheet, W values, and protein contents; B: Highest protein content, lowest β-sheet, and medium W and P/L values. C: Four of the traditional, recently, or not yet cultivated genotypes with the highest bread specific volume, low protein, and W and P/L values. Group D: Traditional genotypes, with the lowest specific volume of bread and a low protein content. Some of the traditional cultivated wheat genotypes in Algeria could be changed, although almost all the drought and disease resistant genotypes could be used for bread-making, which was excellent news because of global warming.
¿Qué tan equilibrado está el multilingüismo en la publicación científica? Un análisis global desde la base de datos del Directory of Open Access Journals (DOAJ)
Authors: del Rio Riande Gimena , Lujano Vilchis Ivonne
Published: May 2024

El concepto de multilingüismo equilibrado (Sivertsen, 2018) busca establecer instrumentos para documentar y medir el uso de una lengua para diferentes propósitos en la investigación, proporcionando así una base para el monitoreo de la globalización de la investigación en una dirección más responsable (p. 2). Sin embargo, un análisis del Directorio de Revistas de Acceso Abierto (DOAJ), la base de datos más grande de revistas en accesoabierto producidas en más de 130 países al día de hoy no muestra ningún multilingüismo equilibrado. DOAJ promueve la diversidad lingüística indexando revistas en 80 idiomas, incluyendo variaciones dialectales, idiomas indígenas e idiomas hablados por menos de 50,000 hablantes (por ejemplo, el aragonés).
En este artículo presentamos las principales tendencias relacionadas con los idiomas en los que las revistas publican sus contribuciones de texto completo para responder a este panorama desequilibrado. Realizamos un análisis descriptivo de las 17,564 revistas listadas en DOAJ hasta abril de 2023. Nuestros hallazgos muestran que el 65% (11,331) de las revistas listadas publican solo en un idioma, y el 35% (6,234) publican en dos, tres y hasta 16 idiomas. La investigación también muestra que el 50% de las revistas multilingües tienen su sede en Asia y América Latina.
Impacts of Climate Changes on Traffic Flows Using Geospatial Data Analysis
Authors: Claver Jimbo Henri , Perin Nagueu Djambong Lionel , Thomas Bouetou , Paul Tchoua
Published: May 2024

This chapter explores the complex interplay between climate change and the accuracy of traffic flow predictions, focusing on the crucial use of geospatial data analysis. The potential effects of extreme weather events, such as heavy precipitation, storms, and heat waves, on traffic patterns should be considered to improve the robustness of traffic management systems. In this study, the authors demonstrate the effectiveness of geospatial data analysis in considering climatic and environmental variables to improve the accuracy of traffic flow forecasts. By integrating data into predictive models, we provide tangible evidence of the impacts of climate change on urban traffic patterns. The results obtained from data and simulations on machine learning models such as Lasso regression, random forest, XGboost and LTSM gave us very good results. prediction performance on the random forest with a correlation coefficient of 0.94; an RMSE of 265 and a MAE of 279 thus demonstrating its effectiveness for predicting traffic flow.
Enhancing Cyber Security Through Generative Adversarial Networks
Authors: Jewani Varkha Kumarlal , Ajmre Prafulla E. , Atique Mohammad , Chaurasia Suhashini
Published: May 2024

GANs, or generative adversarial networks, are becoming a very useful tool in many fields, such as data generation, natural language processing, and computer vision. They still have untapped potential to strengthen cyber security protocols, nevertheless. The uses and ramifications of using GANs to improve cyber security are explored in this abstract. First, by using GANs for data augmentation, realistic and varied datasets that are essential for training malware classifiers, anomaly detection models, and intrusion detection systems can be created. Through the generation of synthetic data that closely mimics real-world cyber threats, GANs enable more thorough and efficient training, strengthening security mechanisms against emerging cyber-attacks in the process. GANs help with security testing and password cracking. This helps security experts assess how strong passwords are and strengthen authentication procedures to fend off possible intrusions.
Enhancing Network Analysis Through Computational Intelligence in GANs
Authors: Bellapukonda Padma , Ayyadurai Sathiya , Mirza Mohsina , Subramaniam Sangeetha
Published: May 2024

In the discipline of allowsrative artificial intelligence, generative adversarial networks have become an effective tool that allow for the creation, modification, and synthesis of extremely realistic content in a variety of domains. This chapter focuses on applying computational intelligence techniques to improve network analysis in GANs. The authors examine the research on GANs' uses in radiology, emphasizing their potential for diagnosis and image enhancement in healthcare. Next, we investigate the application of computational intelligence techniques, like Wasserstein GANs and recurrent neural networks, to enhance training stability and produce higher-quality generated data. In order to increase the accuracy of the generated data even further, they also look into adding other features made with the Fourier transform and ARIMA. Trials show that the information produced by these upgraded GANs can be efficiently used for training energy forecasting models.
Location of metastasis and complications in patients with venous thromboembolism and cancer: systematic review
Authors: Barca-Hernando Maria , Garcia-Garcia Victor , Jara-Palomares Luis
Published: May 2024

According to current guidelines, patients with venous thromboembolism (VTE) and active cancer should receive prolonged anticoagulant treatment (>6 months). In patients with cancer-associated thrombosis (CAT), metastasis is a factor in recurrent VTE and bleeding; however, the function of metastasis location remains unclear. In order to assess the risk of complications (such as bleeding or recurrent VTE) based on the location of metastases in patients with CAT, we conducted a systematic review. The PubMed database search was used to perform a systematic review. MESH terms pertaining to metastasis, VTE, and neoplasms were employed. Patients with CAT who were at least eighteen years old and receiving therapeutic doses of anticoagulants were included, as were details regarding the locations of metastases and the availability of patients who had complications (bleeding or recurrent VTE). Among the 1,447 articles found by the search, 7 retrospective studies met all eligibility requirements and were added to the analysis. The majority of these studies addressed brain metastases. Studies found that intracranial hemorrhage occurred between 4% and 19% of the time. In the context of brain metastases and VTE, other studies examined the safety and effectiveness of direct oral anticoagulants in comparison to low-molecular-weight heparin. This systematic review draws attention to the paucity of data regarding the impact of metastasis location on complications in CAT patients. Further research is required to assess the effect of metastasis location on the risk of VTE complications in patients with CAT.
Endothelial cell dysfunction in cancer: a not-so-innocent bystander
Authors: Ünlü Betül , Joshi Neha , O'Sullivan Jamie M.
Published: May 2024

The body’s homeostasis depends on the vascular endothelium, which controls angiogenesis, vascular tone, inflammation, cell trafficking, hemostasis, and the movement of nutrients and waste out of the body. Endothelial cells (ECs) are the primary gatekeepers of many of these vessel wall functions, despite only having a single cell’s thickness. Normally quiescent ECs in the context of cancer are activated by anti-cancer therapies, the tumor microenvironment, and factors secreted by the tumor. Crucially, this dysfunctional endothelium actively participates in tumor metastasis and progression rather than just acting as a passive bystander. Compared to the healthy vasculature, ECs in the tumor vasculature are heterogeneous and have a different gene expression profile. Tumor-associated ECs, in particular, exhibit increased pro-angiogenic characteristics and upregulated expression of adhesion molecules and proinflammatory cytokines, facilitating the intra- and extravasation of spreading tumor cells. Furthermore, the downregulation of important anticoagulant molecules and increased endothelial secretion of prothrombotic molecules can directly encourage cancer-associated thrombosis. Many anti-cancer therapies are also less effective in their delivery and function when there is dysfunction in the tumor endothelium. The review highlights some of the most recent research showing how tumor-associated ECs influence angiogenesis, inflammation, coagulation, and metastasis to contribute to the progression of tumors. Undoubtedly, a better understanding of how the tumor microenvironment subverts quiescent ECs and how phenotypic alterations in the vessel wall support the survival and spread of tumor cells will aid in the identification of new therapeutic targets to slow the advancement of cancer.
Factor XI inhibitors: a new option for the prevention and treatment of cancer-associated thrombosis
Authors: Di Nisio Marcello , Candeloro Matteo , Potere Nicola , Porreca Ettore , Weitz Jeffrey I.
Published: May 2024

Venous thromboembolism (VTE) is a relatively common complication in cancer patients with potentially dire consequences. Anticoagulants are the mainstay of treatment of cancer-associated VTE. The anticoagulants most often used are low-molecular-weight heparin (LMWH) and direct oral factor (F) Xa inhibitors, which include apixaban, edoxaban, and rivaroxaban. Most guidelines recommend primary VTE prophylaxis with LMWH, apixaban, or rivaroxaban after abdominal or pelvic cancer surgery, or in high-risk ambulatory cancer patients. Both oral FXa inhibitors and LMWH have limitations. LMWH requires daily subcutaneous injections, and because of its renal clearance, its use may be problematic in patients with severe kidney disease. The risk of bleeding with oral FXa inhibitors may be higher than with LMWH in patients with intraluminal gastrointestinal or genitourinary cancers. Other problems with oral FXa inhibitors include potential drug-drug interactions and dosing issues in patients with thrombocytopenia or severe kidney or liver disease. Therefore, there remains a need for convenient and safer anticoagulants for VTE treatment in cancer patients. FXI has emerged as a potentially safer target for anticoagulants than FXa because FXI is essential for thrombosis, but mostly dispensable for hemostasis. This review summarizes the currently available therapeutic options for cancer-associated VTE, highlights knowledge gaps, and discusses the potential of FXI inhibitors to address key unmet clinical needs in this vulnerable patient population.
Machine learning in cancer-associated thrombosis: hype or hope in untangling the clot
Authors: Patell Rushad , Zwicker Jeffrey I. , Singh Rohan , Mantha Simon
Published: May 2024

The goal of machine learning (ML) is to create informative signals and useful tasks by leveraging large datasets to derive computational algorithms. ML has the potential to revolutionize the healthcare industry by boosting productivity, enhancing safe and effective patient care, and lightening the load on clinicians. In addition to gaining mechanistic insights into cancer-associated thrombosis (CAT), ML can be used to improve patient outcomes, streamline healthcare delivery, and spur innovation. Our review paper delves into the present and potential applications of this cutting-edge technology, encompassing three areas: i) computer vision-assisted diagnosis of thromboembolism from radiology data; ii) case detection from electronic health records using natural language processing; iii) algorithms for CAT prediction and risk stratification. The availability of large, well-annotated, high-quality datasets, overfitting, limited generalizability, the risk of propagating inherent bias, and a lack of transparency among patients and clinicians are among the challenges that must be overcome in order to effectively develop ML in the health sector. To guarantee that this powerful instrument can be utilized to maximize innovation in CAT, clinicians can collaborate with stakeholders such as computer scientists, regulatory bodies, and patient groups.
Geospatial epidemiology of coronary artery disease treated with percutaneous coronary intervention in Crete, Greece
Authors: Melidoniotis Evangelos , Kalogeropoulos Kleomenis , Tsatsaris Andreas , Zografakis-Sfakianakis Michail , Lazopoulos George , Tzanakis Nikolaos , Anastasiou Ioannis , Skalidis Emmanouil
Published: May 2024

Coronary artery disease (CAD) constitutes a leading cause of morbidity and mortality worldwide. Percutaneous coronary intervention (PCI) is indicated in a significant proportion of CAD patients, either to improve prognosis or to relieve symptoms not responding to optimal medical therapy. Thus the annual number of patients undergoing PCI in a given geographical area could serve as a surrogate marker of the total CAD burden there. The aim of this study was to analyze the potential, spatial patterns of PCItreated CAD patients in Crete. We evaluated data from all patients subjected to PCI at the island’s sole reference centre for cardiac catheterization within a 4-year study period (2013-2016). The analysis focused on regional variations of yearly PCI rates, as well as on the effect of several clinical parameters on the severity of the coronary artery stenosis treated with PCI across Crete. A spatial database within the ArcGIS environment was created and an analysis carried out based on global and local regression using ordinary least squares (OLS) and geographically weighted regression (GWR), respectively. The results revealed significant inter-municipality variation in PCI rates and thus potentially CAD burden, while the degree and direction of correlation between key clinical factors to coronary stenosis severity demonstrated specific geographical patterns. These preliminary results could set the basis for future research, with the ultimate aim to facilitate efficient healthcare strategies planning.