bluuebunny/crossref_metadata_2025 huggingface dataset:
Mechanism of private funding of higher education in OECD countries and Ukraine
Authors: HRYHORASH Olha
Published: June 2023

The mechanisms of higher education funding in the OECD countries and in Ukraine is considered in the paper. An analysis of the sources of higher education funding was carried out and separate indicators of higher education funding in OECD countries were considered. The mechanism of financial support for obtaining highereducation in countries, where public and private higher education funding prevails, is characterized. The peculiarities of higher education funding in Ukraine at the expense of private sources and the experience of using state loans are analyzed.
Educational trends in the conditions of the russian-Ukrainian war and current geopolitical challenges
Authors: DAVYDOVA Liudmyla , ZAIKO Lesia
Published: June 2023

The article is devoted to the issue of educational trends in the conditions of the Russian-Ukrainian war and the modern geopolitical challenges Ukraine and Ukrainian educators face. The state of quarantine restrictions due to the incidence of Covid-19 caused an active transition of most spheres of activity, including education, communication of educational process to the mixed form with the help of digital technologies. In particular, they became assistants to educators at various levels: from secondary school to institutions of higher education. The adaptation was successful with some shortcomings, which can be solved at the individual level of communication between teachers and students of different levels. Such educational trends as digitalization of the educational process, continuous learning, strengthening of social inclusion, academic integrity, combination of education with science, project-based learning, academic mobility of students and teaching staff, media literacy, psychological support of students in the educational process, recognition of the results of non-formal and informal of education within the educational process, visualization, gamification, interactivity of education, soft-skills: development of social and emotional intelligence,critical thinking, ability to quickly adapt to new conditions, etc. helped all participants of the educational process in Ukraine to boldly adapt to the unusual conditions of long-term quarantine and continue their work even in war conditions. Owing to the financial and material assistance of other countries, it is planned to rebuild destroyed educational institutions and infrastructure according to new standards, develop a new network of educational institutions, and develop in science and technology. The active implementation of educational trends at ZhytomyrIvan Franko State University allows the institution to develop educational directions even in conditions of geopolitical challenges and war.
Strategies of the Russian Companies in the E-Grocery Market
Authors: Andersen D. A.
Published: June 2023

The COVID-19 pandemic, as the main, but not the only factor, led to a rapid increase in consumer demand for grocery delivery services ordered via the Internet (e-grocery), as well as in the revenue of Russian companies on the e-grocery market during the period from 2019 to 2021. This article examines in detail main factors of the external and internal environment that influenced the change in the shares of companies on the Russian e-grocery market and provided strategic competitive advantages to leaders in the long-term period. As the result of studying the market situation during the period from 2019 to 2021, it was revealed that over the three years of the development of the e-grocery market in Russia, in each of the period different players were in the lead. Utkonos, X5 Retail Group and Sbermarket occupied from 13% to 19.5% of the total market. Based on data obtained during the market analysis using SV Matrix, the Russian e-grocery has moved from the stage of formation, competition between small players to the stage of maturity and struggle between consolidated alpha-companies. High entry barriers to a mature market require new companies to have sufficient capacity already at the start to secure their positions.
Quality of sleep and its associated factors among students at Hanoi Medical University
Authors:   School of Preventive Medicine and Public Health, Nguyen Thi Thu Huong , Le Dinh Luyen ,   School of Preventive Medicine and Public Health, Doan Ngoc Thuy Tien ,   School of Preventive Medicine and Public Health, Dam Thi Ngoc Anh ,   School of Preventive Medicine and Public Health, Vo Thi Thuy Ha ,   School of Preventive Medicine and Public Health, Tran Kim Thanh ,   School of Preventive Medicine and Public Health, Dang Quang Tan ,   School of Preventive Medicine and Public Health, Nguyen Thi Kim Ngan ,   Hanoi Medical University, Nguyen Thi Thuy ,   Hanoi Medical University
Published: June 2023

The quality of sleep plays an important role in human health. Objectives: The aim of the study is “To describe the status of sleep quality of students at Hanoi Medical University in 2021 and analyze some associated factors". Methods: A cross-sectional study was carried out among 361 students from the fist year to last year students of 9 majors studying in Hanoi Medical University. Resutls: The percentage of poor sleep quality according to the PSQI scale accounted for 33.8%. Poorer sleep quality in non-exercise students OR=1.99; (95%CI: 1.17-3.37); students had more than 2 hours and above using mobile phones before sleeping OR= 2.69; (95%CI: 1.3-5.56); students waked up in the middle of the night because of cell phones OR= 2.44; (95%CI: 1.37-4.35). Conclusion: The percentage of students with poor sleep quality is high, there should be improvements in students' behavior and healthy living as well as sharing from families and schools to create a comfortable environment for students. Keywords: sleep quality, students, Hanoi Medical University, PSQI (Pittsburgh Sleep Quality Index)
Situation of school myopia and some related factors in students in grades 4 - 5, primary school in tra on town, tra on district, vinh long province in 2022
Authors:   Primary school in tra on town, tra on district, vinh long province, Nguyen Ngoc Tram , Duong Minh Duc ,   Hanoi University of Public Health
Published: June 2023

The study aims to describe the current situation and analyze some factors related to school myopia in students in grades 4 - 5 of primary school in Tra On town, Tra On district, Vinh Long province in 2022. Using a descriptive cross-sectional study with analysis, using a total sampling method with 507 grade 4 and 5 students, assessing myopia by eye examination by an ophthalmologist, evaluating related factors through a set of prepared questionnaires, analyzing data according to research objectives. The rate of students in grades 4 - 5 with myopia is 18,9%. Factors associated with myopia include: family history of nearsightedness; tutoring/studying at home continuously >1 hour; the posture of studying at home is not correct; watch TV frequently and watch TV continuously for >1 hour; frequent use of phone/tablet and continuous use >1 hour; frequent use of computers and continuous use >1 hour; do not regularly play sports/outdoor activities. Keywords: School myopia, Primary school student, related factors.
Psychological distress among undergraduate students of Khanh Hoa Medical College in 2021 and associated factors
Authors:   Khanh Hoa Provincial Center for International Health Quarantine, Bui Duc Trung , Le Huu Tho ,   Nha Trang City Party Committee, Nguyen Thai Quynh Chi ,   Hanoi University of Public Health
Published: June 2023

The study was carried out to describe the psychological disorders of regular students at Khanh Hoa Medical College in 2021 and some related factors. Research method: A cross-sectional study, combining quantitative and qualitative, was conducted from March to October 2021 on over 752 undergraduate students of Khanh Hoa Medical College in 2021. The study used the tool Kessler 6 (K6) with total score from 0-24. The K6 higher score shows that the level of psychological disorder is more severe. The results showed that the rate of psychological disorders among students was 46.5%; accordingly, the mild, moderate and severe levels were 36.4%, 9.3% and 0.8%. Factors related to psychological disorders included: gender, physical health status, school year, previous semester's academic results, playing sports, using alcohol, parents’ marital status, friends care, sharing, helping, frequency of hospital duty. Conclusions and recommendations: With nearly 50% of the students at Khanh Hoa Medical College have psychological disorders, the school needs to have more leisure activities, training classes to help them solve their difficulties. Keywords: Psychological distress, Kessler 6, Khanh Hoa medical college.
Trend of HIV prevalence and risk behaviors among men who have sex with men in Can Tho city and An Giang province, 2017 – 2020
Authors:   HIV/AIDS Global Fund Project, Nguyen Vi Thuy , Bui Thi Tu Quyen ,   Hanoi University of Public Health, Pham Duc Manh ,   Department of HIV/AIDS Prevention and Control
Published: June 2023

Objective: To describe the HIV infection tendencies and risk behaviors among men who have sex with men (MSM) in Can Tho and An Giang between 2017 and 2020. Method: Repeated cross-sectional study design based on the analysis of HIV sentinel surveillance (HSS) data collected in An Giang and Can Tho between 2017 and 2020. A trend analysis is applied to evaluate the changes in HIV infection and high-risk behaviors over time. Result: HIV prevalence is 16.3% of the MSM population, an increase from 14.4% to 19%, with a rising trend among those aged 25 and older. MSMs are increasingly more likely to have sex relationships at younger ages, engage in prostitution, group sexual activity, regularly have sex without using a condom, look for sexual partners online, use stimulants, and have syphilis. The percentage of MSM who receive free condoms, STIs testing and treatment is decreasing. Conclusion: The HIV transmission among MSM in the two middle provinces of the Cuu Long River Delta raises alarm, particularly with the current relatively high rate of HIV infection among young individuals. With the insufficient coverage of HIV preventive programs, several HIV-transmitted risk behaviors worsen. These two provinces should prioritize comprehensive HIV/AIDS prevention interventions with an emphasis on MSM. Key words: Trend analysis, HIV, MSM, risk behaviors, HSS
Health-related quality of life among chronic heart failure patients at the central highlands regional general hospital in 2021
Authors:   Central Highlands Regional General Hospital, Nguyen Ngoc Nhu Khue , Pham Thai Son ,   Vietnam Heart Institute, Le Tu Hoang ,   Hanoi University of Public Health
Published: June 2023

Objective: the study aims to describe the health-related quality of life and identify some associated factors to the quality of life of chronic heart failure out-patients at Central Highlands Regional General hospital. Methods: The study used cross-sectional study on 194 chronic heart failure patients who were aged 18 years old or older at cardiology clinic of the Central Highlands Regional General Hospital and they had a stable medical condition for at least one month before. SF-36 questionaire was used. Main findings: Mean score of health-related quality of life among chronic heart failure patients was medium-good (50.40±18.78). The mean score of quality of life about physical health and mental health was medium–poor (41.14±22.50) and medium–good (59.66±19.48), respectively. Female patients (p=0.044), NYHA classification that was greater than or equal to 3 (p<0,001), having chronic comorbidities (p=0.010) had a lower physical health score than the others. Patients who had higher classification of NYHA (p<0.001) had poorer metal health score than others. Patients who had higher classification of NYHA (p<0.001) and had more comorbidities (p<0.031) had worse health-related quality of life score than others. Conclusion: Quality of life should be assessed periodically during the outpatient treatment of chronic heart failure patients. It is necessary to optimally control the number of chronic comorbidities, improve the NYHA classification to improve the quality of life of patients with chronic heart failure. Keywords: chronic heart failure; health-related quality of life; SF-36.
The Physical Drivers and Observational Tracers of CO-to-H2 Conversion Factor Variations in Nearby Barred Galaxy Centers
Authors: Teng Yu-Hsuan , Sandstrom Karin M. , Sun Jiayi , Gong Munan , Bolatto Alberto D. , Chiang I-Da , Leroy Adam K. , Usero Antonio , Glover Simon C. O. , Klessen Ralf S. , Liu Daizhong , Querejeta Miguel , Schinnerer Eva , Bigiel Frank , Cao Yixian , Chevance Mélanie , Eibensteiner Cosima , Grasha Kathryn , Israel Frank P. , Murphy Eric J. , Neumann Lukas , Pan Hsi-An , Pinna Francesca , Sormani Mattia C. , Smith J. D. , Walter Fabian , Williams Thomas G.
Published: June 2023

The CO-to-H2 conversion factor (α
CO) is central to measuring the amount and properties of molecular gas. It is known to vary with environmental conditions, and previous studies have revealed lower α
CO in the centers of some barred galaxies on kiloparsec scales. To unveil the physical drivers of such variations, we obtained Atacama Large Millimeter/submillimeter Array bands (3), (6), and (7) observations toward the inner ∼2 kpc of NGC 3627 and NGC 4321 tracing 12CO, 13CO, and C18O lines on ∼100 pc scales. Our multiline modeling and Bayesian likelihood analysis of these data sets reveal variations of molecular gas density, temperature, optical depth, and velocity dispersion, which are among the key drivers of α
CO. The central 300 pc nuclei in both galaxies show strong enhancement of temperature T
k ≳ 100 K and density

n

H

2

>

10

3

cm−3. Assuming a CO-to-H2 abundance of 3 × 10−4, we derive 4–15 times lower α
CO than the Galactic value across our maps, which agrees well with previous kiloparsec-scale measurements. Combining the results with our previous work on NGC 3351, we find a strong correlation of α
CO with low-J
12CO optical depths (τ
CO), as well as an anticorrelation with T
k. The τ
CO correlation explains most of the α
CO variation in the three galaxy centers, whereas changes in T
k influence α
CO to second order. Overall, the observed line width and 12CO/13CO 2–1 line ratio correlate with τ
CO variation in these centers, and thus they are useful observational indicators for α
CO variation. We also test current simulation-based α
CO prescriptions and find a systematic overprediction, which likely originates from the mismatch of gas conditions between our data and the simulations.
The 2013 November 12 Solar Energetic Electron Event Associated with Solar Jets
Authors: Wang 王 Wen 雯 , Battaglia Andrea Francesco , Krucker Säm , Wang 王 Linghua 玲华
Published: June 2023

We investigate the hard X-ray (HXR) flare-associated “prompt” solar energetic electron (SEE) 2013 November 12 event with joint EUV jet observations from Solar Dynamics Observatory/Atmospheric Imaging Assembly and STEREO-A/EUVI. The SEE energy spectrum observed by Wind/3D Plasma and Energetic Particle shows a triple-power-law shape with a low-energy break of 10.0 ± 1.7 keV and a high-energy break of 56.6 ± 8.9 keV, which has never been reported before for jet-related SEE events. Associated HXR emissions observed by RHESSI and FGST/Gamma-ray Burst Monitor show three distinctive peaks with different spectral indices β
HPE of HXR-producing electrons (HPEs) derived by means of thick-target bremsstrahlung model. The high-energy spectral index β
3 = 4.63 ± 0.65 of SEE is consistent with the HPE spectral index β
HPE derived in HXR peak 1 but different from β
HPE of HXR peak 2 and peak 3. The main stream of EUV jets reaches a speed of 370 ± 25 km s−1 after an acceleration of up to 2.9 ± 0.4 km s−2 in a timescale of ∼2 minutes, and the acceleration time coincides with the decay phase of HXR peak 1. EUV observations from two different viewing directions help to reconstruct the jet magnetic configurations. After the investigation on HXR emissions and jet configurations, the interchange-reconnection model triggered by the emerging flux could be a satisfactory explanation for this jet event.
Stellar Parameters and Chemical Abundances Estimated from LAMOST-II DR8 MRS Based on Cycle-StarNet
Authors: Wang Rui , Luo A-Li , Zhang Shuo , Ting Yuan-Sen , O’Briain Teaghan ,   LAMOST MRS Collaboration
Published: June 2023

Deriving stellar atmospheric parameters and chemical abundances from stellar spectra is crucial for understanding the evolution of the Milky Way. By performing a fitting with MARCS model atmospheric theoretical synthetic spectra combined with a domain-adaptation method, we estimate the fundamental stellar parameters (T
eff, log g, [Fe/H], v
mic, and v
mac) and 11 chemical abundances for 1.38 million FGKM-type stars of the Medium-Resolution Spectroscopic Survey (MRS) from LAMOST-II DR8. The domain-adaptation method, cycle-starnet, is employed to reduce the gap between observed and synthetic spectra, and the L-BFGS algorithm is used to search the best-fit synthetic spectra. By combining the Two Micron All Sky Survey photometric survey data, Gaia EDR3 parallax, and MIST isochrones, the surface gravities of the stars are constrained after estimating their bolometric luminosities. The accuracy of T
eff, log g, and [Fe/H] can reach 150 K, 0.11 dex, and 0.15 dex, evaluated by the PASTEL catalog, asteroseismic samples, and other spectroscopic surveys. The precision of these parameters and elemental abundances ([C/Fe], [Na/Fe], [Mg/Fe], [Si/Fe], [Ca/Fe], [Ti/Fe], [Cr/Fe], [Mn/Fe], [Co/Fe], [Ni/Fe], and [Cu/Fe]) is assessed by repeated observations and validated by cluster members. For spectra with signal-to-noise ratios (S/Ns) greater than 10, the precision of the three stellar parameters and elemental abundances can achieve 76 K, 0.014 dex, 0.096 dex, and 0.04–0.15 dex. For spectra with S/Ns higher than 100, the precision stabilizes at 22 K, 0.006 dex, 0.043 dex, and 0.01–0.06 dex. The full LAMOST MRS stellar properties catalog is available at doi: 10.12149/101242.
OSSOS. XXVII. Population Estimates for Theoretically Stable Centaurs between Uranus and Neptune
Authors: Dorsey Rosemary C. , Bannister Michele T. , Lawler Samantha M. , Parker Alex H.
Published: June 2023

We calculate the upper bounds of the population of theoretically stable Centaur orbits between Uranus and Neptune. These small bodies are on low-eccentricity, low-inclination orbits in two specific bands of semimajor axis, centered at ∼24.6 and ∼25.6 au. They exhibit unusually long Gyr-stable lifetimes in previously published numerical integrations, orders of magnitude longer than that of a typical Centaur. Despite the increased breadth and depth of recent Solar System surveys, no such objects have been found. Using the Outer Solar System Origins Survey simulator to calculate the detection efficiency for these objects in an ensemble of fully characterized surveys, we determine that a population of 72 stable Centaurs with absolute magnitude H

r
≤ 10 (95% confidence upper limit) could remain undetected. The upcoming Legacy Survey of Space and Time will be able to detect this entire intrinsic population, due to its complete coverage of the ecliptic plane. If detected, these objects will be interesting dynamically accessible mission targets—especially as comparison of the stable Centaur orbital phase space to the outcomes of several modern planetary migration simulations suggests that these objects could be close to primordial in nature.
Medication Cost Concerns and Disparities in Patient-Reported Outcomes Among a Multiethnic Cohort of Patients With Systemic Lupus Erythematosus
Authors: Aguirre Alfredo , DeQuattro Kimberly , Shiboski Stephen , Katz Patricia , Greenlund Kurt J. , Barbour Kamil E. , Gordon Caroline , Lanata Cristina , Criswell Lindsey A. , Dall’Era Maria , Yazdany Jinoos
Published: June 2023

Objective

Concerns about the affordability of medications are common in systemic lupus erythematosus (SLE), but the relationship between medication cost concerns and health outcomes is poorly understood. We assessed the association of self-reported medication cost concerns and patient-reported outcomes (PROs) in a multiethnic SLE cohort.

Methods

The California Lupus Epidemiology Study is a cohort of individuals with physician-confirmed SLE. Medication cost concerns were defined as having difficulties affording SLE medications, skipping doses, delaying refills, requesting lower-cost alternatives, purchasing medications outside the United States, or applying for patient assistance programs. Linear regression and mixed effects models assessed the cross-sectional and longitudinal association of medication cost concerns and PROs, respectively, adjusting for age, sex, race and ethnicity, income, principal insurance, immunomodulatory medications, and organ damage.

Results

Of 334 participants, medication cost concerns were reported by 91 (27%). Medication cost concerns were associated with worse Systemic Lupus Activity Questionnaire (SLAQ; beta coefficient [β] 5.9, 95% CI 4.3-7.6;P< 0.001), 8-item Patient Health Questionnaire depression scale (PHQ-8; β 2.7, 95% CI 1.4-4.0;P< 0.001), and Patient-Reported Outcomes Measurement Information System (PROMIS; β for physical function −4.6, 95% CI −6.7 to −2.4;P< 0.001) scores after adjusting for covariates. Medication cost concerns were not associated with significant changes in PROs over 2-year follow-up.

Conclusion

More than a quarter of participants reported at least 1 medication cost concern, which was associated with worse PROs. Our results reveal a potentially modifiable risk factor for poor outcomes rooted in the unaffordability of SLE care.
Psychiatric Morbidity Is Common Among Children With Juvenile Idiopathic Arthritis: A National Matched Cohort Study
Authors: Pedersen Malthe Jessen , Høst Christian , Hansen Stefan Nygaard , Deleuran Bent Winding , Bech Bodil Hammer
Published: June 2023

Objective

Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease that causes joint inflammation and pain. Previous studies have indicated affected mental health and increased risk of psychiatric conditions among patients with JIA. We aimed to explore differences in psychiatric morbidity between children with JIA and their peers. We further studied if parental socioeconomic status (SES) influences the association between JIA and the risk of psychiatric morbidity.

Methods

We used a matched cohort design to estimate the association between JIA and psychiatric disease. Children with JIA, born between 1995 and 2014, were identified in Danish national registers. Based on birth registers, we randomly selected 100 age- and sex-matched children per index child. Index date was the date of the fifth JIA diagnosis code or the date of matching for reference children. End of follow-up was the date of psychiatric diagnosis, death, emigration, or December 31, 2018, whatever came first. Data were analyzed using a Cox proportional hazard model.

Results

We identified 2086 children with JIA with a mean age at diagnosis of 8.1 years. Children with JIA had a 17% higher instantaneous risk of a psychiatric diagnosis when compared with the reference group, with an adjusted hazard ratio of 1.17 (95% CI 1.02-1.34). Relevant associations were found only for depression and adjustment disorders. Stratifying our analysis for SES showed no modifying effect of SES.

Conclusion

Children with JIA had a higher risk of psychiatric diagnoses compared to their peers, especially diagnoses of depression and adjustment disorders. The association between JIA and psychiatric disease did not depend on parental SES.
Alerte enlèvements !
Authors: Raiman Pierre
Published: June 2023

Le Japon est le premier producteur de jeux vidéo à l’eau de rose. Appelés « jeux pour jeunes filles » ( otome gēmu ), ils proposent des gammes de « beaux gosses » formatés sur le modèle du prédateur, entraînant l’héroïne dans une histoire d’amour proche du rapt. Les scénarios reposent sur la mise en scène d’une perte de pouvoir, où la joueuse renonce à son libre arbitre. Les personnages les plus agressifs sont « irrésistibles », expliquent les fans qui désirent être « prises au piège ». En étudiant ces jeux et les tensions qu’ils révèlent, j’espère éclairer les dynamiques sociales dont ils reproduisent, et déconstruisent, les logiques. Ils sont indissociables du contexte qui les a vu naître : celui d’une baisse record du nombre de mariages et de naissances, pour lesquelles les autorités désignent comme coupables les « personnes qui vivent seules » ( o-hitori-sama ). Pourquoi préfèrent-elles des partenaires fictifs aux hommes de chair et d’os ? J’y vois l’expression d’une ambivalence à l’égard du mariage, désiré mais redouté.
Production de l’ignorance dans le contexte de l’autoritarisme conservateur en Russie : éléments d’analyse
Authors: Buduchev Vitaly , Le Marec Joëlle
Published: June 2023

Cet article est une contribution à la réflexion sur différentes formes de communications publiques dans un régime autoritaire, dans la Russie contemporaine. Il n’est pas fréquent de les évoquer au prisme de la fabrique de l’ignorance. Celle-ci résulte de plusieurs niveaux de contrôle : celui des discours étatiques (qui se confond avec la parole du chef), celui de l’action législative (qui détermine les conditions de possibilité de la parole critique) et celui des discours médiatiques. L’article se concentre sur certaines mesures contraignant la liberté d’expression au sein de l’espace public russe, sur les effets conjugués de l’action normative, communicationnelle et législative du pouvoir. Enfin, on considère les médias comme un moyen d’assurer une circulation des représentations du conservatisme comme cadre commun : l’ignorance collective résulte aussi de l’impossibilité du débat et du dialogue.
Le Yémen sur la voie de la paix ?
Authors: Mermier Franck
Published: June 2023

La reconnaissance, à Sanaa en avril 2023, des rebelles houthistes par le régime saoudien entérine la division politique du pays, dont l’unité menace toujours d’éclater.
La fabrique de l’étranger à Mayotte
Authors: Roinsard Nicolas
Published: June 2023

Les dispositifs politiques de production de l’étranger à Mayotte se heurtent au fait que les Mahorais et les étrangers partagent une même culture bantoue-islamique, ainsi que d’étroits liens de parenté.
Nouveaux fragments d’une mémoire infinie (V)
Authors: Renouard Maël
Published: June 2023

Dans ce cinquième volet de son enquête littéraire, Maël Renouard s’interroge sur la résurgence de termes tombés en désuétude, sur nos avatars durant les confinements et sur la multitude numérique face à l’empire des réseaux sociaux. Montaigne y critique le « registre des visages ».
Dans le miroir de Boutcha
Authors: Timofeeva Oxana , Chalier Jonathan
Published: June 2023

Le massacre de l’armée russe à Boutcha témoigne d’une pulsion de mort collective retournée contre le peuple ukrainien. Au lieu de se laisser emporter par la tempête de la révolution, la nation russe neutralise l’antagonisme social dans une guerre.
Quand l’art-thérapie soigne les soignants : Les effets des productions artistiques des patients sur la qualité de vie au travail des personnels soignants en cancérologie
Authors: Canolle Fabien , Bernard Nathalie , Vinot Didier
Published: June 2023

Nous cherchons à comprendre les effets de l’art-thérapie, exercée avec les patients en soins palliatifs en oncologie, sur la qualité de vie au travail (QVT) des personnels soignants. Nous l’étudions dans la perspective de la clinique de l’activité, i.e. , de la qualité du travail, en étudiant comment l’art-thérapie contribue à l’organisation du dialogue sur la qualité du travail et au développement du pouvoir d’agir des soignants dans un contexte hospitalier contraint. Nous menons une enquête dans un service de médecine palliative en cancérologie, avec trois modes de collecte de données (entretiens, focus group et observations). L’art-thérapie s’inscrit dans un dispositif de soin en participant à la transformation de l’environnement du travail, de la relation avec les patients, et de l’organisation coordonnée du travail du soin. Cela participe d’un mouvement dialogique, éthique et esthétique permettant de soigner le travail du soin et les soignants par le développement de leur pouvoir d’agir.
Les problèmes de maintenance dans l’industrie : un symptôme, mais de quoi ?
Authors: Messulam Pierre , Villette Michel
Published: June 2023

La dégradation de la qualité de la maintenance dans les industries de réseau se traduit par une multiplication des incidents, des pannes, et des arrêts de production. Cet entretien, fondé sur l’expérience professionnelle de Pierre Messulam, tente de saisir les ramifications causales de cette dégradation, symptôme d’un problème systémique de la société technologique du XXI e  siècle, particulièrement en France. La conjonction de transitions économiques, démographiques et techniques mal anticipées et mal gérées, aussi bien par le système éducatif que par les services publics de transport et d’énergie, ont conduit à une perte de savoir-faire. Le recours massif à la sous-traitance, les réductions d’effectifs touchant en particulier les agents de maitrise, le report des investissements de renouvellement des actifs, et l’espoir magique mis dans des solutions numériques ont pu masquer pendant un temps les tendances de fond de dégradation des systèmes sociotechniques. Or, les outils de métrologie et de modélisation saisissent imparfaitement le réel. Les écrans d’ordinateur ne montrent que des corrélations entre des données. Et un cahier des charges même très précis ne peut pas dire tout ce qu’il faut faire pour que ça marche.
Polyphasic identification of a Zygosaccharomyces rouxii isolated from grape juice concentrate and its control using thermal processing
Authors: Lee Wu-Joo , Nielsen Barbara , Younce Frank L. , Edwards Charles G. , Ünlü Gülhan
Published: June 2023

A yeast, isolated from grape juice concentrate by a grape juice processing company in central Washington, was subjected to thermal processing in 52° Brix grape juice concentrate, commercial grape juice, and Yeast-Mold (YM) medium to determine D-values and z-values in the search for an effective means of control. At 50 ℃ in grape juice concentrate the D-value was 33.44 minutes, dropping rapidly as the temperature increased to 52.5 ℃, 55 ℃, 57.5 ℃, and 60 ℃. From this data, a z-value was determined to be 4.38 ℃. Grape juice and YM broth were similarly tested. Commercial grape juice at 45 ℃, 47 ℃, and 50 ℃ showed D-values of 9.80, 7.68, and 1.42, respectively, resulting in a z-value of 5.69 ℃. The isolate heat treated in YM broth at 40 ℃, 45 ℃, 46 ℃, 47.5 ℃, and 50 ℃ showed no effect at 40 ℃ but at higher temperatures, with a D-value of 2.28 at 45 ℃, 1.61 at 46 ℃, 1.05 at 47.5 ℃, and with a z-value of 7.46 ℃. This data suggests that an increase in the concentration of sugars in the environment has a protective effect on the yeast against elevated temperatures. Even so, pasteurization at 90 ℃ for thirty seconds appears to be an effective means of control for the yeast investigated. A yeast with the identical colony and cell morphology was isolated from 52° Brix grape juice concentrate from the same grape juice processing company. Both isolates were subjected to 28S DNA sequencing and FAME analysis for identification and determined to be Zygosaccharomyces rouxii, a known problem yeast in the grape juice and wine-making industry, to this point unknown in the central Washington region.
Controllability of fractional stochastic evolution inclusion via Hilfer derivative of fixed point theory
Authors: Moumen Abdelkader , Alsinai Ammar , Shafqat Ramsha , Albasheir Nafisa A. , Alhagyan Mohammed , Gargouri Ameni , Almazah Mohammed M. A.
Published: June 2023

In this study, we use the Hilfer derivative to analyze the approximate controllability of fractional stochastic evolution inclusions (FSEIs) with nonlocal conditions. By assuming that the corresponding linear system is approximately controllable, we obtain a novel set of adequate requirements for the approximate controllability of nonlinear FSEIs in meticulous detail. The fixed-point theorem for multi-valued operators and fractional calculus are used to achieve the results. Finally, we use several instances to demonstrate our findings.
An adversarially consensus model of augmented unlabeled data for cardiac image segmentation (CAU+)
Authors: Cheng Wenli , Jiao Jiajia
Published: June 2023

High quality medical images play an important role in intelligent medical analyses. However, the difficulty of acquiring medical images with professional annotation makes the required medical image datasets, very expensive and time-consuming. In this paper, we propose a semi-supervised method, $ {\mathrm{C}\mathrm{A}\mathrm{U}}^{+} $, which is a consensus model of augmented unlabeled data for cardiac image segmentation. First, the whole is divided into two parts: the segmentation network and the discriminator network. The segmentation network is based on the teacher student model. A labeled image is sent to the student model, while an unlabeled image is processed by CTAugment. The strongly augmented samples are sent to the student model and the weakly augmented samples are sent to the teacher model. Second, $ {\mathrm{C}\mathrm{A}\mathrm{U}}^{+} $ adopts a hybrid loss function, which mixes the supervised loss for labeled data with the unsupervised loss for unlabeled data. Third, an adversarial learning is introduced to facilitate the semi-supervised learning of unlabeled images by using the confidence map generated by the discriminator as a supervised signal. After evaluating on an automated cardiac diagnosis challenge (ACDC), our proposed method $ {\mathrm{C}\mathrm{A}\mathrm{U}}^{+} $ has good effectiveness and generality and $ {\mathrm{C}\mathrm{A}\mathrm{U}}^{+} $ is confirmed to have a improves dice coefficient (DSC) by up to 18.01, Jaccard coefficient (JC) by up to 16.72, relative absolute volume difference (RAVD) by up to 0.8, average surface distance (ASD) and 95% Hausdorff distance ($ {HD}_{95} $) reduced by over 50% than the latest semi-supervised learning methods.
A Quantitative Approach for the Accurate CFD Simulation of Hover in Turbulent Flow
Authors: Chaderjian Neal M.
Published: June 2023

Time-dependent Navier–Stokes simulations have been carried out for a V22 rotor in hover using an improved, lowdissipation, HLLE ++ upwind algorithm in the OVERFLOW code. Emphasis is placed on lessons learned over the past decade regarding the effects of high-order spatial accuracy,
grid resolution, and the use of detached eddy simulation in predicting the figure-of-merit, the rotor's chief performance parameter. A general quick-start procedure is described together with a statistical measure of FM convergence that reduces hover computations by fourfold, similar to computational
work for forward flight. Cartesian adaptive mesh refinement is used to resolve the tip–vortex to its correct physical size. This adaptive mesh refinement in the rotor wake also revealed a complex turbulent flow with worm-like structures of various scales. These structures were numerically
found a decade ago and recently observed in experiment.
Transgender population in the Russian Federation: diversity and trends
Authors: Solovieva Nadezhda V. , Makarova Ekaterina V. , Kremenitskaya Svetlana A.
Published: June 2023

This report presents socio-demographic data of gender incongruent patients, searching for gender affirming medical care (GAMC) in Russia by retrospective medical records analysis of patients. Data of 1117 patients were included in the analysis. Over the period from 2014 to 2021, there was a significant increase in the number of applications (+123.2%). Among all transgender individuals 44.01% were trans femine (MtF) and 55.99% (n=630) were trans masculine (FtM), 1.2% was non-binary persons. The average age for GAMC application in MtF was 26 years and in FtM was 23 years. Majority of patients experienced gender incongruence (GI) since pre-pubertal age (median 11.0). Age of acceptance oneself as a "transgender " was 17.0 years, earlier in FtM, later in MtF. The first coming-out was made at 20 (22 for MtF, 19 for FtM). Depression was diagnosed in 82,4% cases,12.6% of patients have suicide attempts. 53.6%, were already taking hormonal therapy (76.7% MtF, 32.3% FtM). The Russian transgender population is big, stigmatized, ethnically and culturally heterogeneous group, that has little visibility. Further research is essentials for formation of professional attitude in the medical environment.
A Young Boy with Gynecomastia
Authors: Hasan Md. Mahmud , Ansari M. A. Jalil , Prasad Indrajit , Saifuddin Mohammad , Islam Moinul , Sharifuzzaman Mirza , Alam Mohammad Jahangir , Sutradhar Palash Chandra , Khan Mohammad Shohel , Najifa Wafia
Published: June 2023

Ovotesticular disorder of sex development (ovotesticular DSD) is defined as the presence of testicular and ovarian tissue in the same individual. Both external and internal genitalia of patients with ovotesticular DSD display a spectrum of phenotypes. Most children present with ambiguous genitalia in combination with unilateral or bilateral undescended gonads. We present late-diagnosed boy who presented with bilateral enlargement of the breast (gynecomastia) and male external genitalia. One should consider the possibility of ovotesticular DSD when managing boys with gynecomastia.
Clinical and Hormonal Profile of Polycystic Ovary Syndrome Phenotypes
Authors: Hossain Mohammad Afjal , Pathan Md Faruque , Afsana Faria , Sharifuzzaman Mirza , Amin Farzana , Kabir Md Lutful , Mahmud Nusrat , Saifuddin Mohammad , Qureshi Nazmul Kabir , Selim Shahjada , Kamrul-Hasan A. B. M.
Published: June 2023

Background:

Polycystic ovary syndrome (PCOS) is a heterogeneous androgen-excess disorder with varying degrees of reproductive and metabolic abnormalities, whose diagnosis is based on anthropometric, biochemical, and radiological abnormalities. This study was conducted to observe the frequency of different phenotypes of PCOS and to observe the pattern of clinical profile and hormonal changes among them.

Methods:

This cross-sectional observational study was conducted at the Endocrinology and Obstetrics and Gynecology Outpatient Department of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine, and Metabolic Disorders over the period of 13 months, dated from April 2016 to April 2017. Eighty patients clinically diagnosed as a case of PCOS were included in this study as per inclusion and exclusion criteria. Patients were categorized into four different phenotypes based on the presence of oligo-anovulation (O), hyperandrogenism (H), and polycystic ovarian morphology (P): (i) Phenotype A (O + H + P), (ii) Phenotype B (O + H), (iii) Phenotype C (H + P), and (iv) Phenotype D (O + P). Demographic, clinical, anthropometric, and hormonal profiles were recorded and compared among phenotypes of PCOS by ANOVA and Chi-square test.

Results:

Most prevalent phenotype in the study population was Phenotype A (55%), followed by Phenotype D (22.5%), Phenotype B (15%), and Phenotype C (7.5%). Hirsutism, acne, acanthosis nigricans, and family history of diabetes mellitus were more common in Phenotype A and Phenotype B than in Phenotype C and Phenotype D (P < 0.001, P = 0.029, P = 0.008, and P = 0.048, respectively). Relatively, higher body mass index, waist circumference, and waist–hip ratio were found in Phenotypes A and B than in other phenotypes (P < 0.001, P < 0.001, and P < 0.001, respectively). Phenotypes A and B had higher serum total testosterone, luteinizing hormone (LH), free androgen index, and lower sex hormone-binding globulin than other phenotypes (P = 0.003, P = 0.007, P = 0.001, and P < 0.001, respectively). Follicle-stimulating hormone (FSH), LH/FSH ratio, prolactin, and thyroid-stimulating hormone were comparable in all phenotypes (P 0.445, 0.204, 0.748, and 0.811, respectively).

Conclusions:

The PCOS in certain subgroups such as Phenotypes A and B had higher hyperandrogenism and was associated with adverse anthropometric and clinical parameters. Clinical and hormonal findings are different in different phenotypes.
Promising Response with PI3K Inhibitor for a Patient with Heavily Pretreated PIK3CA Mutation Head-and-Neck Cancer
Authors: Lee Ming-Jing , Kao Hsiang-Fong
Published: June 2023

The treatment options for patients with head-and-neck squamous cell carcinoma (HNSCC) are limited when the disease progresses after taking platinum, a PD-1 inhibitor, and cetuximab. To develop new agents for managing such pretreated malignancies, therapies targeting carcinogenic pathways could be possible in HNSCC patients. Several pathways have been identified in HNSCC, including the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway. The PI3K/AKT/mTOR pathway is frequently dysregulated in various cancers due to activating mutations or amplification of PIK3CA. The inhibition of this pathway has been proven to improve clinical outcomes in some malignancies with PIK3CA mutations. We report a heavily pretreated HNSCC patient with a good treatment response to alpelisib, a PI3K inhibitor. Furthermore, we discuss the possible limitations of alpelisib monotherapy and possible solutions to overcome these limitations.
Small Pancreas Neuroendocrine Tumors: How Small is Small?
Authors: Chen Ming-Huang , Hsieh Chia Hsun , Yang Ching-Yao , Tsai Hui-Jen , Chen Li-Tzong ,   On Behalf of Taiwan Neuroendocrine Tumor Society
Published: June 2023

Objective:

The current study aimed to investigate the issues in contemporary management strategies that focus on small pancreatic neuroendocrine tumors (PNETs).

Data Sources and Study Selection:

We searched various scientific databases using specific keywords.

Results:

Surveillance-only strategies were considered for selected patients. The exact cut-off value of small neuroendocrine tumors for surveillance-only strategies needs to be verified with additional high-level evidence.

Conclusion:

There is no consensus on the size and treatment strategy for small PNETs currently. Patients with small nonfunctioning PNETs require individualized recommendations for surgery versus active surveillance based on tumor size, radiographic characteristics, and patient characteristics, such as age and comorbidities and also patient references.
Pneumothorax during Alectinib Treatment for a Uterine Inflammatory Myofibroblastic Tumor with Lung Metastasis
Authors: Lin Chang-Ting , Wu Chen-Hsuan , Huang Hsuan-Ying , Liu Chien-Ting
Published: June 2023

An inflammatory myofibroblastic tumor (IMT) is an uncommon sarcoma subtype with histopathological features, including inflammatory infiltrates. Anaplastic lymphoma kinase (ALK) gene rearrangement has been reported in half of the patients with IMTs; therefore, crizotinib, an ALK inhibitor, may achieve a response rate of 50% in these patients. We present a case with an initial diagnosis of uterine sarcoma and multiple lung metastases. After the failure of doxorubicin-based chemotherapy, revised pathology from a palliative hysterectomy revealed an IMT with ALK gene rearrangement. Treatment with alectinib achieved an excellent tumor response. The accurate differential diagnosis of uncommon sarcoma subtypes is crucial because a specific targeted therapy may considerably alter treatment outcomes.
Adjuvant Chemotherapy in Patients with Low-Risk Epithelial Ovarian Cancer: A Taiwanese Cohort Study
Authors: Lo Yuan-Ting C. , Ku Hsiu-Ying , Chang Cheng-Shyong , Ch’ang Hui-Ju , Ho Chih-Ming , Liu Tsang-Wu , Lin Shih-Min
Published: June 2023

Background:

Whether or not patients with stage I epithelial ovarian cancer (EOC) benefit from postoperative chemotherapy in the Asian population remains unclear. This retrospective cohort study was aimed at investigating the use of adjuvant chemotherapy in clinical practice to treat patients with early-stage EOC considering clinical factors.

Materials and Methods:

A total of 414 patients with the International Federation of Gynecology and Obstetrics (FIGO) stage IA–IC and grade 1 EOC were enrolled from the Taiwan Cancer Registry. We used multivariable Cox proportional-hazards models to control for clinical factors. The overall survival (OS) and disease-free survival (DFS) were estimated with the Kaplan–Meier method.

Results:

DFS did not improve significantly for patients with FIGO stage IA/IB EOC receiving adjuvant chemotherapy, with a 10-year DFS rate of 98% and 88% for those with and without adjuvant chemotherapy, respectively (hazard ratio [HR] = 0.41, 95% confidence interval [CI]: 0.05–3.36). OS did not improve significantly for patients with FIGO stage IA/IB EOC with adjuvant chemotherapy (HR = 0.86, 95% CI: 0.18–4.22) or stage IC (HR = 0.50, 95% CI: 0.10–2.45). OS did not differ significantly for patients with optimal (10-year OS: 92% with chemotherapy and 86% without chemotherapy in the log-rank test, P = 0.629) or nonoptimal staging (10-year OS: 73% with chemotherapy and 90% without chemotherapy in the log-rank test, P = 0.959).

Conclusion:

Adjuvant chemotherapy did not improve the prognosis of patients with low to intermediate-risk EOC and optimal/nonoptimal surgery. This result should be considered in clinical practice.
Left Ventricular Strain in Systemic Diseases
Authors: De Aniruddha
Published: June 2023

Systemic diseases consist of various pathological conditions with a wide range of symptoms, often with progressive clinical worsening. Cardiac involvement is not uncommon in many of these conditions. Subclinical myocardial dysfunction is the common manifestation during the early stages of the disease and recognition of early myocardial dysfunction is very important for diagnosis and future prognosis. Left ventricular ejection fraction (LVEF) is considered less sensitive to detect early LV myocardial dysfunction. Strain imaging, performed using speckle-tracking echocardiography (STE), has emerged as a robust tool for detecting early subclinical myocardial dysfunction. The longitudinal muscle fibres are predominantly found in the sub-endocardium and are more susceptible to damage since the sub-endocardium is comparatively less perfused. Hence, longitudinal strain is impaired early in the course of the disease and helps in detecting subtle cardiac involvement in various systemic diseases. Global longitudinal strain, which is the average longitudinal strain of all the LV myocardial segments, is currently the most useful strain parameter for this purpose.
Left Atrial Strain: Crucial Cardiac Navigator in Practice
Authors: Sengupta Shantanu P. , Agarwal Ashish
Published: June 2023

Left ventricular (LV) diastolic pressure estimation is essential for characterization of heart failure. Despite extensive research and the availability of numerous metrics, the assessment of LV diastolic pressures both at rest and after exertion has been challenging. Left atrial strain assessment by echocardiography has recently shown promise in correlating with LV end-diastolic pressure. This review provides information about this novel technology.