bluuebunny/crossref_metadata_2025 huggingface dataset:
Ethanol inhibited growth hormone receptor-mediated endocytosis in primary mouse hepatocytes
Authors: Ge Zihan , Liu Xingjie , Yang Yu , Hainan Lan , Zhang Yawen , Zhang Wei , Xian Li , Li Ruonan
Published: November 2024

Objectives

Growth hormone (GH) exhibits various essential physiological functions, which are exerted by its binding to growth hormone receptor (GHR). Ethanol has been demonstrated to have an impact on GH’s biological activity. Nevertheless, mechanism underlying the regulation of the biological activity of GH by ethanol have yet to be fully elucidated.

Methods

This study utilized an indirect immunofluorescence assay to identify GHR expression in mouse hepatocytes. Western blot was used to determine the impact of ethanol on GH-induced intracellular signalling. Indirect immunofluorescence and colocalization experiments were used to determine the effect of ethanol on GH-GHR’s nuclear localization and endocytosis.

Results

GHR was primarily localized in the cell membrane and cytoplasm. The phosphorylation levels of JAK2 and STAT1/3/5 were markedly lowered after treatment with ethanol. On this basis, we further explored the mechanism underlying the regulation of GH biological activity by ethanol from the perspective of cell internalization. We found that the nuclear translocation of GH-GHR was inhibited when treated with ethanol. In addition, the results of colocalization analyses revealed that ethanol inhibited GHR-mediated nuclear translocation may mainly by inhibiting caveolin-dependent endocytosis.

Conclusions

Our study showed that ethanol inhibits GH signaling ability in a time-dependent manner. Ethanol could inhibit the nuclear localization of GH-GHR, which may be linked to the inhibition of the interaction between GHR and caveolin. The combined effect of these factors downregulated the GH-GHR signal. This study laid a foundation for further exploring the mechanism that the effects of ethanol on GH biological activity.
Terminal Pleistocene–Early Holocene human occupation in north-central Chile
Authors: Troncoso Andrés , Pascual Daniel , Escudero Antonia , Pino Mariela , Hernández Daniel , López-Méndoza Patricio , Moya Francisca , Armstrong Felipe , Vera Francisca , Delgado Manuela , Artigas Diego , Larach Pablo , Chávez María Alejandra
Published: November 2024

While a clear human presence may be recognised in the Andes by 12 000–11 000 cal BP, most archaeological research has focused on occupation of the Andean highlands. To understand the initial occupation of inland areas of South America, the authors consider regional connections and spatial exploitation strategies of hunter-gatherers highlighted in a recent survey of Andean sites. Focusing on north-central Chile, artefacts and radiocarbon dates from three rock shelters suggest sporadic and brief occupation during the Terminal Pleistocene–Early Holocene. Co-occurrence of marine and montane resources, the authors argue, demonstrates a strategy of high mobility and local adaptation in early Andean occupation, using rock shelters as landmarks to navigate and learn new landscapes.
Untwisting Beycesultan Höyük: the earliest evidence for nålbinding and indigo-dyed textiles in Anatolia
Authors: Maner Çiğdem , Abay Eşref , Karadağ Recep , Torgan Güzel Emine
Published: November 2024

Cuneiform tablets indicate the importance of textile manufacturing in the Bronze Age Old Assyrian Colony Period and Hittite Empire, yet the organic traces of this industry rarely survive. Two burnt textile fragments found at Beycesultan offer an unexpected insight into the Bronze Age textile industry in Anatolia. Here, the authors present the results of chromatographic and microscopic analyses that indicate one fragment was made from hemp using the nålbinding, or single-needle knitting, technique and was dyed with the woad or indigo plant, while the other was a natural tabby weave. Both add to our understanding of the diversity of textile production in the Bronze Age.
ENGINEERED CHITOSAN NANOPARTICLES FOR ENCAPSULATION OF THYMOL
Authors: Arserim-uçar Dılhun Keriman
Published: November 2024

This study successfully obtained chitosan thymol nanoparticles using an electrohydrodynamic technique, which is a simple one-step procedure. The morphological and physical characterization, antioxidant, and antimicrobial activity assessments of electrosprayed thymol-loaded chitosan nanoparticles (CTNPs) were carried out. The ABTS assay and the agar well diffusion test were used to determine the antioxidant and antimicrobial activities of the CTNP samples, respectively. The results showed that CTNPs possessed efficient antimicrobial capacity against B. cereus, S. aureus, E. coli, and S. typhimurium. CTNPs indicated a radical scavenging activity of 90% regarding the ABTS assay. CTNPs with biological activities could be an effective alternative for practical food safety and health applications. In this study, the use of electrohydrodynamic atomization technique to produce biopolymer nanoparticles present a novel approach for encapsulating thymol-like volatile active agents.
The Effect of Aural and Visual Presentation Formats on Categorical and Dimensional Judgements of Emotion for Sung and Spoken Expressive Performances
Authors: Miksza Peter , Tan Daphne , Potter Robert F. , Booth McCall
Published: November 2024

The purpose of this study was to investigate the effects of visual information on the perception of emotion in three contexts: a short spoken phrase, an analogous short melody, and a longer melody with greater complexity of pitch and rhythm. Participants without substantial formal music training were assigned to either an audio-only, visual-only, or audiovisual presentation mode; all observed musicians and actors who sang melodies or spoke phrases intending to communicate happiness, sadness, or anger. Participants rated these performances for positive and negative valence, energy arousal, and tension arousal. They were also asked to select the discrete emotion they perceived, and to rate how certain they were about this selection. Participants perceived energy arousal and tension arousal as fairly distinct features of the performances and the performances were perceived as having clear dimensional characteristics based on intended emotion (e.g., happy performances had the highest positive valence, lowest negative valence, etc.). Regarding presentation, participants in the audiovisual mode categorized emotional intentions with greater accuracy than those in the others. Although ratings of negative valence, energy, and tension ratings were more extreme for actors than for musicians, participants were most in agreement about the valence of the actors’ sung performances.
Effects of Melodic Contour on Sung Speech Intelligibility in Noisy Environments in Musicians and Nonmusicians
Authors: Hsieh I-Hui , Liu Jia-Wei
Published: November 2024

Using songs to facilitate speech processing in noisy environments seems appealing and practical. However, current research suggests otherwise, possibly due to the simplicity of sung speech contours. This study investigates the effects of contour tonality on sung speech intelligibility in noisy environments. A cohort of 20 trained musicians and 20 nonmusicians were tested on the intelligibility of Mandarin sentences sung on tonal, atonal, and fixed-pitch melodies or normally spoken under three signal-to-noise ratios (SNRs: −3, −6, and −9 dB). Perceptual musical skills related to speech-in-noise perception were also assessed. Results showed that overall speech-in-noise intelligibility decreased as the SNR decreased, with spoken speech being more intelligible than sung speech. Sung speech intelligibility was higher for fixed- than variable-pitch contours, with no difference between tonal and atonal melodies. No musician advantage was reported for spoken speech. Musicians, nonetheless, outperformed nonmusicians in identifying sung speech across all melodic contour types. Moreover, the musician sung speech advantage correlated with enhanced music perception abilities on pitch and accent. These results suggest that musicians have an advantage in sung speech in noisy environments. However, melody tonality provided no additional benefits, suggesting that imposing tonality on sung speech does not improve speech perception in noisy environments.
Features of hear microelement composition in children with type 1 diabetes mellitus
Authors: Yunatskaya Tatyana A. , Turchaninov Denis V. , Vlasenko Natalya Yu. , Vilms Elena A. , Shcherba Elena V.
Published: November 2024

Objective: Assessment of the characteristics of the microelement composition of the hair of children with type 1 diabetes mellitus (T1DM) to develop recommendations for diet correction. Material and methods. The study involved children with T1 DM (n=28) and practically healthy children from the comparison group (n=56) aged 3-5 years living in the Omsk region. The elemental composition of hair was analyzed by atomic emission and mass spectrometry with inductively coupled argon plasma. The research materials were subjected to statistical processing using nonpara-metric criteria. Results. The elemental profile of hair of children with T1 DM has been determined. Significant differences were found in the amounts of microelements in hair: lower values of beryllium (p=0.0001), chromium (p=0.003), lithium (p=0.005), vanadium (p=0.005), selenium (p=0.043), and large amounts of cuprum (p=0.025), phosphorus (p=0.001) in the hair of children with diabetes in comparison with the group of practically healthy ones. In the group of children with T1DM, there was a smaller proportion of people with insufficient magnesium (p=0.003), phosphorus (p=0.001), and cuprum (p=0.001). The severity of mineral metabolism disorders (MMD) was less in the group of children with T1DM: 53.6% of children were classified as having no MMD or having minor MMD. Conclusions. The elemental composition of the hair of children with T1DM was characterized by higher amounts of phosphorus and cuprum, lower content of chromium, selenium, beryllium, lithium and vanadium. The proportion of children with insufficient supply of magnesium, phosphorus, cuprum was higher in the comparison group. The degree of MMD in the group of children with T1 DM was generally less.
Collaboration of inter university research in the field of experimental surgery
Authors: Alipov Vladimir V. , Rykhlov Andrey S. , Tuchina Elena S. , Skripal Anatoly V. , Shipovskaya Anna B. , Musaelyan Ara G. , Gritsai Ulyana O. , Alieva Sofia G.
Published: November 2024

The article presents historical milestones and traditions laid down by S. I. Spasokukotsky in the development of experimental surgery in Saratov. The procedure and principles of conducting surgical experiments on laboratory animals are described. Twenty years of experience in interuniversity experimental research are summarized, the stages of postoperative treatment of abscesses of various localizations, based on computer modeling of a surgical experiment and modern technologies, are given. It has been shown that combining the knowledge and resources of interuniversity research teams in conducting a surgical experiment makes it possible to achieve better treatment results in clinical surgery.
Mandibulada Multilokuler Görünümlü Multiple Myelom: Radyografik Bulgularla Olgu Sunumu
Authors: Çam Kübra , Zengin Ayşe Zeynep
Published: November 2024

Amaç: Multiple myelom (MM), plazma hücrelerinin kemik iliğinde anormal immunoglobulin üretmeleri ile karakterize malign bir hastalıktır. Genellikle mandibulada kortikal yapı içermeyen, iyi sınırlı zımba deliği şeklinde radyolusent görüntü verir. Bu olgu sunumunun amacı, MM tanılı hastada farklı radyografik bulgular gösteren mandibular lezyonun sunulmasıdır.
Olgu sunumu: 49 yaşında MM tanılı erkek hasta bifosfonat kullanımı öncesi kliniğimize başvurdu. Panoramik radyografda sol mandibula angulus bölgesinde 2. ve 3. molar dişlerin apekslerini ve inferior alveolar kanalı içine alan, 3. molar dişte kök rezorpsiyonuna sebep olmuş, lobüle iyi sınırlı multiloküler görünümlü radyolüsent alan ve ramus orta kısmında iyi sınırlı zımba deliği görünümlü radyolüsent lezyon izlendi. Mevcut bilgisayarlı tomografi görüntülerinde aksiyel kesitlerde mandibula ramus bölgesinde hafif ekspansiyon gösteren, bukkal ve lingual kortikal kemiği inceltip yer yer destrükte eden, lobüle zayıf sınırlı homojen, hipodens kemik lezyonu görüldü.
Sonuç: Klinisyenlerin mandibulada görülen kistik veya multiloküler görünümlü lezyonların ayırıcı tanısında MM lezyonlarını da göz önünde bulundurmaları gerekmektedir.
Türkiye’deki Diş Hekimlerinin COVID-19 Farkındalığının Değerlendirilmesi: Bir Kesitsel Çalışma
Authors: Ibrahımov Ismayıl , Önder Mustafa Ercüment , Basmacı Fulya , Keleş Ayşe , Çizmeci Şenel Figen , Tekin Umut
Published: November 2024

Amaç: Bu çalışmada COVID-19 salgını döneminde Türkiye’de çalışan diş hekimlerinin COVID-19'la ilgili bilgi düzeyinin ve farkındalığının değerlendirilmesi amaçlanmaktadır.
Gereç ve Yöntemler: Çalışmamız Türkiye genelinde üniversite hastanelerinde, ağız ve diş sağlığı merkezlerinde ve özel poliklinik ve muayenehanelerde çalışan diş hekimleri üzerinde uygulanmıştır. Türk diş hekimlerinin COVID-19 enfeksiyonu hakkındaki farkındalığını değerlendirmek için çevrimiçi anket kullanılmıştır. Çalışma yapılmadan önce güç analizi kullanılarak örneklem büyüklüğü hesaplanmış ve 700 katılımcı olarak belirlenmiştir. Toplam 42 sorudan oluşturduğumuz çevrimiçi anket formu 5 bölümden oluşturulmuştur.
Bulgular: Bu süreçte diş hekimleri acil ve zorunlu hizmetler dışındaki tedavileri yapmaları konusunda hastaların baskısı ile karşılaştıklarını (509 kişi), hasta veya yakınları tarafından şiddete maruz kaldıklarını (152 kişi) bildirmiştir. COVID-19 enfeksiyonunu ciddi bir halk sağlığı sorunu olarak yorumlayan diş hekimi sayısı 738 (% 95.9) dir. 681 (% 88.5) diş hekimi bu enfeksiyonla ilgili Sağlık Bakanlığı tarafından ilan edilen rehber, sunum ve güncellemeleri rutin olarak takip ettiğini bildirmiştir. Ayrıca 82 (% 10.6) diş hekimi bu dönemde diş hekimliği ile ilgili alınan önlemlerin diş hekimi ve yardımcılarının korunması için yeterli olduğuna “tamamen katılıyorum” şeklinde, 195 (% 25.3) diş hekimi ise “katılıyorum” şeklinde cevap vermiştir.
Sonuçlar: diş hekimlerinin, COVID-19 semptomları ve bulaşma yolları, KKE kullanımı, diş hekimliği kliniklerinde bu enfeksiyonun yayılma riskinin daha fazla olması konusunda farkındalığının yüksek olduğu saptanmıştır.
Anahtar Kelimeler: Covid-19, Diş hekimleri, Farkındalık
Sarkopenik veya Olası Sarkopenik Hastaların Ağız Sağlığı Durumunun Değerlendirilmesi
Authors: Mevlanaoğlu Uzun Merve , Coskun Akar Gulcan , Alpöz Esin , Daylan Ayşe , Kılavuz Aslı , Kayhan Koçak Fatma Özge , Savaş Sumru
Published: November 2024

Amaç: Fiziksel yetersizlik, düşük yaşam kalitesi ve ölüm gibi kötü sonuçlara yol açabilen, jeneralize ve progresif kas kütlesi ve kuvvet kaybı ile karakterize bir sendrom olarak tanımlanan ve görülme sıklığı yaşla artış gösteren sarkopenik durumların ağız sağlığı üzerindeki etkisinin değerlendirilmesi amaçlandı.
Gereç ve Yöntemler: Çalışmaya Ocak 2021-2022 tarihleri arasında sarkopeni ön tanısı ile değerlendirilen yaşları 66-103 arasında değişen 27’si kadın (% 69.2) 39 olgu (olası sarkopeni 9 kişi, sarkopeni 8 kişi, normal 22 kişi) dahil edildi. Sarkopeni EWGSOP2 kriterlerine göre tanımlandı. Bölgesel değerlendirmelerde el kavrama gücü kesim noktaları erkeklerde 32 kg, kadınlarda ise 22 kg olarak alındı. Tüm olguların ağız içi değerlendirmeleri (ağız açma miktarı, ağız içi protez kullanım durumları ve çeşitleri) diş hekimi tarafından kaydedildi. Ağız içi algısı için Yaşlı Ağız Sağlığı Tanılama İndeksi (YASTİ) kullanıldı.
Bulgular: Tüm olgularda ağız açma miktarı normal değerlerde olup kontrol grubunun ağız açma miktarı sarkopeni grubunda daha yüksek olduğu gözlendi (p=0.013). Olgulardan sadece sekiz tanesi ağız protezi kullanmamakta, sarkopeni gruplarında yer almayan ve alt üst tam dişsiz olan bir olgunun protez gereksinimi bulunmaktadır. Ağız protezi gereksinimi olmayan sarkopeni ve olası sarkopeni grubunda yer alan birer olgunun indeks değerinin ‘orta’ olduğu, normal olarak değerlendirilen grupta ise ‘yüksek’ değer kaydedilmediği gözlendi. Sarkopeni ve YASTİ arasındaki ilişki anlamsız bulundu (p≥0.05).
Sonuçlar: Kısıtlı örneklem grubu üzerinde yapılan çalışmada sarkopeni verileri ile YASTİ arasında anlamlı korelasyon bulunmadı. Bununla birlikte sarkopenili hastaların ağız açıklığı miktarının daha düşük olduğu saptandı. Sarkopeninin YASTİ üzerindeki etkisini belirlemek için daha geniş popülasyon çalışmalarına ihtiyaç duyulmaktadır.
Anahtar Kelimeler: Olası Sarkopeni, Sarkopeni, Yaşlı Ağız Sağlığı Tanılama İndeksi
A tipi silikonların temas açısı ve çekme testi ile karşılaştırılması
Authors: Demir Necla , Çapar Zişan
Published: November 2024

Amaç: Bu çalışmanın amacı sürfaktan ve nanopartikül içeriği farklı a tipi silikon ölçü materyallerine temas açısı/ıslanabilirliği (contact angle) ve çekme testi (tensile strenght) uygulanarak materyallerin çekme dayanıklılığı ve hidrofilik özelliklerini değerlendirmektir.
Yöntem: Çalışmamızda a tipi polivinil siloksan ölçü materyallerinden nanopartikül ve sürfaktan içerikleri farklı olan Zhermack Elite Hd (Ivoclar, Vivadent, Lienchenstein, Germany) ile Imicryl Spirias (Konya, Türkiye) kullanılmıştır. Temas açısı testi ve çekme testi için 20’şer örnek hazırlanmıştır. Dataphysics Oca 50 micro cihazında başlangıç olarak 0.138 sn. ve bitiş olarak 82.8. sn.deki temas açısı ölçümleri yapılmıştır. DVT GPE 13888 YBS cihazda 50 mm/dk hızda çekme testi uygulanmıştır. Numunelerin koptuğu anda uygulanan kuvvet Fmax (Mpa), çekme uzama yüzdesi (ΔL) ve elastik modülüsü (E= N/mm²) kayıt edilmiştir. Sonuçlar IBM SPSS V23 ve RStudio ile analiz edilmiştir.
Bulgular: Temas açısı ölçüm değerleri arasındaki fark istatistiksel olarak anlamlı bulunmuştur (p
Comparison of the Effect of Adhesive Protocols and Light Curing Units on the Repair Bond Strength of Bulk Fill Composite Resins
Authors: Bilge Kübra , İpek İrem , Aşar Enes Mustafa
Published: November 2024

Background: The aim of this study is to compare the shear bond strength (SBS) after the repair of a microhybrid composite resin (CR) with three different bulk fill CRs using a 2nd and 3rd generation light-emitting diode (LED) light curing units and a universal adhesive with different application protocols.
Methods: 120 acrylic blocks, each with an open surface and a depth of 2 mm and a diameter of 6 mm, were filled with a microhybrid CR (Filtek Z250) and cured with an LED for 20 seconds. The samples were roughened for 5 seconds with a diamond fissure bur under water cooling and then subjected to 5,000 thermal cycles. A universal adhesive was applied to the prepared samples using two different protocols (total etch and self-etch), and samples were then filled with bulk fill CRs. Each bulk fill CR group was polymerized with 2nd and 3rd generation LED to form subgroups (n=10). The SBS values were recorded in MPa using a universal testing device.
Results: The highest SBS values were obtained for the X-tra Fil group in total etch mode with polymerization using 3rd generation LED, while the lowest SBS values were found for Filtek One Bulk Fill group in self-etch mode with polymerization using the 3rd generation LED. In all groups, total etch mode yielded higher SBS values compared to self-etch mode.
Conclusion: Different adhesive protocols and LCUs were found to affect the SBS values of bulk fill CRs during repair.
Hepatitis C Virus Testing Among Perinatally Exposed Children: 2018 to 2020
Authors: Woodworth Kate R. , Distler Samantha , Chang Daniel J. , Luong Jackie , Newton Suzanne , Akosa Amanda , Orkis Lauren , Reynolds Bethany , Carpentieri Cynthia , Willabus Teri , Osinski Anthony , Shephard Hanna , Halai Umme-Aiman , Lyu Caleb , Sizemore Lindsey , Sandul Amy , Tong Van T.
Published: November 2024

OBJECTIVE

To assess the frequency of hepatitis C virus (HCV) testing among a population-based cohort of perinatally exposed children and identify factors associated with testing.

METHODS

Using a population-based surveillance cohort of perinatally exposed children born from 2018 to 2020 from 4 US jurisdictions (Georgia; Massachusetts; Allegheny County, Pennsylvania; and Los Angeles County, California), we describe the frequency, timing, and type of HCV testing among children and identify characteristics associated with having an HCV test result by the age of 2 to 3 years. Data were obtained from electronic laboratory reporting, vital records, and medical records.

RESULTS

Of 803 perinatally exposed children, 7 (1%) died before the age of 24 months. Of 796 children, health departments were unable to find medical records or laboratory reports for 181 (23%). Among those with medical record abstraction at 24 months or testing reported before the age of 3 years (n = 615), 50% had an HCV test. The majority (70% of those tested) were tested for HCV antibodies at the age of 18 months or later, although 9% had an HCV nucleic acid test at ages 2 to <6 months. No characteristics examined were found to be significantly associated with having testing reported.

CONCLUSIONS

In this surveillance report, we identify the gaps in current testing among children perinatally exposed to hepatitis C. Provider education and resources for health departments for follow-up and linkage to care can improve the identification of children requiring treatment, a vital piece of HCV elimination.
Bioestimulación radical y radiación solar en plantas en vivero de Coffea arabica L.
Authors: Aguilar-Luna Jesús Mao , Hernández-Vargas Liliana , Hernández-Ángel Rodolfo
Published: November 2024

Introducción. En etapa de vivero se pueden conformar plantas de Coffea arabica con calidad, que reduzcan los efectos estresantes después del trasplante, que aumenten la eficiencia fotosintética y que mantengan una tasa de crecimiento constante. Objetivo. Evaluar el efecto de bioestimulantes y radiación solar en el crecimiento y fisiología de plantas de C. arabica en etapa de vivero. Materiales y métodos. Los experimentos se realizaron dentro de un microtúnel en la Benemérita Universidad Autónoma de Puebla, México; cada cual duró 270 días, realizados en 2018 y 2022. En un diseño factorial en bloques; factor 1 (bioestimulantes: testigo, hongos micorrízicos, algas marinas y polímeros orgánicos), factor 2 (radiación: 81, 168, 278 y 440 µmol m-2 s-1), factor 3 (variedades: Costa Rica 95, Marsellesa, Caturra Roja y Garnica). Se determinó: colonización micorrízica (CM), proporción del sistema radical (PSR), tasa de crecimiento (TC), proporción de parte aérea (PPA), clorofilas y contenido nutricional. A los datos se les realizó un ANOVA para detectar diferencias entre tratamientos. Resultados. A los 270 días después de la siembra, la variedad Marsellesa bioestimulada con hongos micorrízicos y expuesta a una irradiancia de 168±36 µmol m-2 s-1, alcanzó valores altos en CM con 36,51 % y TC  con 0,175 g g-1 día. En Costa Rica 95 y Marsellesa, la bioestimulación con polímeros y una irradiancia de 440±59 µmol m-2 s-1, se relacionó significativamente (p≤0,05) con incrementos de 3,08 mg g-1 PMF en clorofila total. En Marsellesa se obtuvieron contenidos nutricionales altos en N, P, K, Ca y Mg, al bioestimular con polímeros y 168±36 µmol m-2 s-1 de irradiancia. Conclusiones. La bioestimulación radical con hongos micorrízicos y niveles de irradiación de 168 a 278 µmol m-2 s-1, propiciaron un mejor desarrollo en plantas de cafeto.
The relationship between attorney and judge: an ethical dilemma
Authors: Duliba Yevheniia , Teremetskyi Vladyslav
Published: November 2024

The relevance of this research lies in clarifying the nature of the relationship between an attorney and a judge in the context of power dynamics, professional ethics and interpersonal communication. The purpose of the study is to determine the role of professional ethics in shaping the relationship between an attorney and a judge, as well as the impact of personal relationships between attorneys and judges on the judicial decision-making process. The methodological basis of the study is general scientific and special legal methods of knowledge, in particular philosophical dialectic, comparative legal, idealisation and formalisation methods. The materials used for this study are the works of domestic and foreign scholars, and the provisions of national, foreign and international legislation.
The results of the study show that the relationship between an attorney and a judge is inherently complex, dynamic and critical, since it is at the intersection of legal norms, professional ethics and personal interactions.
The relationship between attorneys and judges is an important component of the judicial process, as it affects the efficiency and fairness of decisions. These relationships are formed through a complex interplay of historical, ethical, professional, as well as personal interactions. Effective communication, mutual respect and a clear understanding of the role of each party are crucial to strengthen constructive relationships.
The findings of the study indicate that a constructive relationship between judges and attorneys is an important element in ensuring the integrity of the legal system. Adhering to established ethical standards and maintaining an atmosphere of mutual respect and professionalism, judges and attorneys promote the administration of justice in accordance with the needs of all participants in the process, thereby increasing the level of trust and reliability of the judicial system
Selection of the optimal formulation of the biopolymer system for the stimulation of productive formations
Authors: Rubel Viktoria , Slichenko Roman
Published: November 2024

The object of study in this paper is the biopolymer system «X» – a complex composition that includes a biopolymer, salts and a thermal stabiliser intended for use in drilling fluids at high temperatures. The components of the formulation include complex reagent «X» for regulating structural, mechanical, rheological and filtration properties, as well as inhibitors (sodium and potassium chloride) and filler. Components of the biopolymer system (sodium chloride, organo-mineral colmatant thermal stabiliser) increase its thermal stability. One of the most problematic areas is the mechanism of sodium chloride's thermal stabilising effect. It is associated with an increase in the overall mineralisation of the drilling mud, which leads to a certain conformation of biopolymer molecules, accelerates gelation processes and counteracts the temperature dilution of the system.
The results obtained can be explained as follows:
– an increase in the concentration of sodium chloride leads to an increase in the ionic strength of the solution, which contributes to a change in the conformation of biopolymer molecules, enhancing intermolecular interactions and, as a result, increasing the viscosity and stability of the system;
– the organo-mineral colmatant heat stabiliser promotes the formation of a filtration crust on the well walls, which prevents fluid loss and reduces rock permeability;
– all components of the system interact with each other, affecting the properties of the solution. The optimum ratio of components allows achieving the required rheological characteristics and ensuring the stability of the system at high temperatures.
As a result of processing the information on technologies for tapping productive horizons, the disadvantages and advantages of each of them were noted. The existing drilling fluid systems used to tap productive horizons at high temperatures were considered. However, more attention was paid to the selection of a new optimal formulation of the biopolymer system, in accordance with the specified rheological and structural and mechanical properties for further implementation in practice. This ensures the possibility of obtaining predictive parameters of the drilling mud.
The proposed system has a number of advantages over similar ones, namely:
– the system retains its properties at high temperatures;
– the system provides the required values of viscosity, filtration and static shear stress;
– due to the use of an optimal formulation, high efficiency is achieved at a relatively low cost.
Conversa evânica: por uma outra genealogia do ensaio
Authors: Magalhães Danielle
Published: November 2024

Resumo O século do ensaio foi o século da colonização e da queima de milhares de mulheres europeias e não europeias. Segundo a filósofa e historiadora Silvia Federici, dentre as mulheres acusadas de bruxaria estavam aquelas que partilhavam uma amizade subversiva, seja como modo de se aliarem e resistirem à violência arbitrária de seus maridos e da sociedade patriarcal, seja como uma cumplicidade entre mulheres que abortavam, espontaneamente ou não, contra o imperativo estatal de procriar. Se o ensaio nasce, como gênero, associado à amizade, com Montaigne, como seria pensar outra genealogia do ensaio como um gênero que nascesse da amizade subversiva dessas mulheres que foram queimadas como “bruxas” por fazerem um uso não racional e não ocidental da linguagem, como, por exemplo, conversar com a serpente?
Estudos Literários em questão: paradoxo ou utopia?
Authors: Costa Cristina Henrique da
Published: November 2024

Resumo Uma análise da situação dos Estudos Literários no Brasil evidencia que a riqueza de sua diversificação não tem resultado numa pacífica convivência de seus estudiosos. Na contramão das explicações habitualmente mobilizadas, este artigo propõe então investigar os motivos teóricos do fenômeno de polarização dos Estudos Literários partindo da vontade de assumir um problema teórico interno à disciplina. Em seu aspecto paradoxal, as teorias de literatura, quaisquer que sejam, definem seu objeto de estudo através de um discurso normativo implícito ou explícito. O artigo sugere que tal aspecto paradoxal pode ser revertido através do uso das ferramentas da hermenêutica: círculo, paradigma e conflito. Por fim, a partir da ideia de conflito das interpretações e com o apoio da hermenêutica crítica de Paul Ricœur, conclui-se pela possibilidade de compreender melhor, e talvez de ultrapassar a polarização atual dos Estudos Literários.
La Forme de l’essai comme théorie critique
Authors: Couto Elvis Paulo
Published: November 2024

Résumé L’objectif principal de cet article est de démontrer, dans l’argumentation de « L’essai comme forme », de Theodor Adorno, l’existence d’un ensemble cohérent de prolégomènes à une théorie dialectique de la critique littéraire. Il s’agit de voir dans quelle mesure les attributs de la forme de l’essai peuvent être compris comme des principes d’interprétation de l’œuvre littéraire et quelles limites et contributions l’entendement adornien de ces principes présente pour l’actuel débat épistémologique de la théorie littéraire.
Comunidade de Prática de Enfermagem: conectando enfermeiros e enfermeiras na Região das Américas
Authors: Dias Bruna Moreno , Pérez Johel Nazareth Díaz , Cassiani Silvia Helena de Bortoli
Published: November 2024

Objetivo: analisar o perfil de utilização e o conteúdo das mensagens da Comunidade de Prática de Enfermagem da Região das Américas da Organização Pan-Americana da Saúde como ferramenta voltada ao compartilhamento de experiências, conhecimentos e oportunidades para enfermeiros e enfermeiras. Método: estudo descritivo e qualitativo, cujo objetivo foi analisar as mensagens publicadas nos fóruns da Comunidade de Prática. Os dados foram analisados por meio de análise de conteúdo. Resultados: a Comunidade de Prática permitiu a participação de 1765 profissionais de 20 países, com 4001 mensagens publicadas. Os temas analisados (educação, emprego, liderança e prestação de serviços) foram abordados na perspectiva de profissionais de diferentes países, apresentando os desafios que enfrentam e os suas reflexões sobre a situação da Enfermagem na Região. Conclusão: a plataforma permitiu que profissionais de diferentes países e áreas interagissem e debatessem temas relevantes para o ensino e a prática da Enfermagem na Região das Américas. Através da Comunidade de Prática, espera-se aumentar o compromisso, a cooperação e a solidariedade para a aprendizagem coletiva e o desenvolvimento de capacidades, maximizando a contribuição dos enfermeiros com os serviços e sistemas de saúde.
Padrão de uso de smartphones e tablets em crianças de até cinco anos de idade na Espanha: um estudo transversal
Authors: Paz-Cantos Sonia de , González-Marrón Adrián , Lidón-Moyano Cristina , Cerrato-Lara Maria , Díez-Izquierdo Ana , Martínez-Sánchez Jose M
Published: November 2024

Objetivo caracterizar o padrão de uso de smartphones e tablets em uma amostra de crianças de até cinco anos de idade e avaliar com quais variáveis ele está associado. Método estudo transversal com 410 pais de crianças de até cinco anos de idade. Os dados foram obtidos por meio de um questionário online . Foram coletadas perguntas sobre o tempo e o padrão de uso diário de smartphones e tablets . Calculamos a porcentagem geral (e o intervalo de confiança de 95%) e a mediana (e o intervalo interquartil) do tempo de uso de cada dispositivo, de acordo com as variáveis associadas à criança e as características do entrevistado. Resultados estima-se que 44,7% (IC 95%: 37; 51) das crianças usavam smartphones e/ou tablets diariamente. O tempo médio de uso de smartphones e tablets, separadamente, foi de 30 minutos por dia para smartphones (8,6-38,6) e 30 (17,1-60,0) para tablets . Nas crianças que têm acesso livre aos dispositivos, 11,6% (IC 95%: 6; 16) usam esses dispositivos até 30 minutos depois de acordar durante a semana, 15,4% (IC 95%: 10; 21) durante os finais de semana e 14,0% (IC 95%: 8; 19) usam smartphone e/ou tablet até 1 hora antes de dormir. Conclusão mais de quatro em cada dez crianças de nossa amostra usavam smartphones e/ou tablets diariamente. A enfermagem comunitária pode ser um caminho viável para a implementação de programas educacionais voltados para a promoção de práticas saudáveis no uso de dispositivos eletrônicos por crianças, dado o padrão de uso excessivo de telas na população pediátrica.
Assessment of physicochemical characteristics and bioactive compounds of the essential oil of wild herbs aromatic from Andean region of South Perú
Authors: Barrial-Lujàn A. I. , Taipe-Pardo F. , Lima-Roman P. , Correa-Cuba O. , Aroni-Huamán J. , Salas-Villano T. S. , Solano-Gutierrez J. , Machaca Rejas J. , Barrial-Lujàn C. , Arevalo-Quijano J. C. , Huamán-Carrión M. L.
Published: November 2024

Abstract Essential oils are a subject of study due to the heterogeneity of their components, which vary according to the genus and species of the plant material. The objective of this study was the physicochemical characterization and bioactive components of the essential oil (EO) extracted from wild punamuña (Satureja Boliviana) and runtuhuayra (Clinopodium Weberbaueri (Mansf.) Govaerts) herbs from high Andean areas of southern Peru. The extraction of the EO from both species was carried out using the steam distillation technique, the density characterization using gravimetric methods and the acidity, peroxide index and refraction by analytical methods recommended by the Norma Tecnica Peruana (NTP). The bioactive compounds were quantified using gas chromatography coupled to a mass spectrometry detector (GC-MS). A better EO performance was obtained from punañuna 0.38% (w/w) compared to runtuhuayra 0.28% (w/w); In both samples, the density and refractive index were similar values (0.93-0.94) g/mL and (1.528-1.520) (p>0.05) respectively; However, the acid and peroxide index showed a significant difference between the samples studied (p<0.05). 37 bioactive compounds synthesized as secondary metabolites in Satureja Boliviana EO were identified, with the majority being monoterpenes (62%) highlighted by menthone, L-menthone, pulegone and 3-cyclohexen-1-one. 2-isopropyl-5-methyl, linalool, α-cadinene and α-cadinol; Meanwhile, in the EO of Clinopodium Weberbaueri, 28 compounds were detected and quantified, in which monoterpenes predominate (61%) made up of pulegone (45.67%); isomenthol (13.85%), menthone (6.05%), carvacrol (5.39%), and also D-limonene; o-cymene; 3-octanol; β-pinene and α-terpineol successively. This characterization of the EO of the aforementioned samples reveals recent a new additive or ingredient alternative for the industry due to its biological value associated with antioxidant, antimicrobial, anti-inflammatory activities and psychotherapeutics.
Evolution of the use of conversational agents in business education: Past, present, and future
Authors: Bohorquez-Lopez Victor Wilfredo
Published: November 2024

Abstract Purpose: The primary objective of this article is to answer the proposed research questions by analyzing the publications on artificial intelligence (AI), education, business, and conversational agents (CAs) or chatbots within the Scopus database to identify the most frequent terms used by scholars over the years, as well as to classify the research evolution based on the most important thematic trends. Originality/value: The study contributes to the literature by offering insights into the thematic landscape of AI-related research across multiple domains. By employing a comprehensive methodology, the article provides a nuanced understanding of the intersection between AI, education, business, and CAs. Design/methodology/approach: The methodology comprises two main components. Firstly, topic modeling is applied by the year of publication to summaries of articles meeting the search criteria. Secondly, grounded theory coding was used to categorize generated themes into more meaningful classifications. This dual approach ensures a rigorous data analysis and facilitates the identification of overarching thematic trends. Findings: The results reveal five thematic trends investigated in the analyzed publications: 1. student-centered learning in higher education; 2. interactive methods using the natural language processing (NLP) approach; 3. technological solutions and ChatGPT in a university context; 4. enhancing education through intelligent platforms; and 5. challenges for social and academic integration of AI tools. Additionally, the study proposes a research agenda with some questions as future avenues of inquiry.
Physicochemical characterization of fresh and germinated bean and cowpea varieties
Authors: Rodrigues Larissa M. de S. , Queiroz Alexandre J. de M. , Figueirêdo Rossana M. F. de , Albuquerque Junior Nailton de M. , Paiva Yaroslávia F. , Santos Francislaine S. dos , Amadeu Lumara T. S. , Melo Bruno A. de , Gomes Josivanda P.
Published: November 2024

ABSTRACT Beans are a vital component of the human diet, being able to supply a large part of the daily protein requirements of individuals, in addition to containing considerable amounts of iron, calcium, vitamins, carbohydrates, fiber, and lysine. Controlled germination is an accessible and effective technique that aims to improve the nutritional, functional, and sensory qualities of seeds intended for food consumption. This study aimed to characterize fresh and germinated beans of Phaseolus vulgaris (carioca, branco, preto, gordo varieties) and Vigna unguiculata (cowpea). The germination process was conducted in trays containing the sand substrate (350 g) in the environmental conditions of the laboratory. The fresh and germinated beans were evaluated for physicochemical variables in triplicate. The germination process increased moisture content, water activity, ash, pH, soluble alcohol acidity, proteins, ascorbic acid, phenols, tannins, flavonoids, anthocyanins, and carotenoids. On the other hand, there was a reduction in the content of lipids, starch, and total sugars in bean seeds. With the increase in bioactive compounds, it was found that the germination process is an excellent method for increasing the nutritional quality of beans.
Energy performance of sugarcane harvesters equipped with knives and saws for basal cutting
Authors: Marques Filho Aldir C. , Testa João V. P. , Martins Murilo B. , Bortolheiro Fernanda P. de A. P. , Almeida Pablo L. de , Lanças Kléber P.
Published: November 2024

ABSTRACT The mechanized cutting of sugarcane requires improvements, as cutting tools can affect the longevity of sugarcane fields and increase production costs. Furthermore, these tools can increase the energy demand of machines in the field. This study evaluated the sugarcane harvester performance equipped with different basal cutting devices: impact cutting (blades) and continuous cutting (saws) in three commercial sugarcane production areas. The experimental design was completely randomized in a 3 × 2 factorial scheme with six repetitions. Effective fuel consumption and harvesting capacity were evaluated. The saws increased fuel consumption per area by 3.9 and 8.9% per Mg harvested. The crop’s yield characteristics determine harvesting systems’ energy demand. For yields above 90 Mg ha-1, energy demand has stabilized up to 120 Mg ha-1. The fuel demand for harvesting ranged between 1.0 and 1.2 L Mg-1 of harvested material. Regardless of the cutting system, each Mg requires 37.3 kJ of energy to be removed from the field.
Bio-electrical properties of apples in function of sample volume and temperature and probe configuration
Authors: Cai Honghao , Wu Jiaqing , Chen Jiashun , Xu Gongqin
Published: November 2024

ABSTRACT The quality of fruit can be quickly and accurately assessed using bio-impedance spectroscopy, but no comprehensive studies have been conducted on how the detection conditions affect their bio-electrical properties. Accordingly, this study aims to investigate the effects of sample volume, sample temperature, probe depth and probe distance on the bio-electrical properties of apples and uses a controlled bi-variable method to determine the optimal parameter settings, thus providing researchers with reliable references. Two different measurement methods, the spike method and the contact method, are used to measure the electrical properties of apples under various conditions and to compare the results. It is verified that the effects of sample volume, temperature, probe depth, and probe distance on bio-electrical properties follow physical laws when using the spike method. The contact method, however, is prone to errors and is not suitable for large-scale samples. The optimal conditions for the spike method, determined by a bi-variable approach, are sample volume of 20 cm3 (5 × 2 × 2 cm), probe distance of 2.5 cm at 1 kHz and 1 cm at 20 kHz, and probe depth of 1 cm.
De Inezita Barroso a Marília Mendonça: o legado de violeiras e cantoras na música caipira e sertaneja
Authors: Guerra Luiz Antonio , Rebelo Francine
Published: November 2024

Resumo Este artigo busca problematizar a memória da música caipira e sertaneja, enfatizando a contribuição das mulheres em meio à hegemonia masculina, desde a década de 1930 até os dias de hoje, em função de sua conexão histórica com culturas rurais tradicionais. Na primeira parte do texto, sobre as violeiras, como na segunda, sobre as cantoras e as compositoras, são analisadas as trajetórias, os obstáculos e as estratégias das artistas em sua luta por reconhecimento nesse estilo musical quase centenário.
Implications of seed coat cracking on soybean seed quality
Authors: Teixeira Sheila Bigolin , Zorato Maria de Fátima , Meneghello Geri Eduardo
Published: November 2024

ABSTRACT: Seed coat cracking is a “physiological defect” that occurs in soybean seeds, affecting their integrity. The objective of this study was to evaluate the effect of seed coat cracking on the physiological quality and storability of soybean seeds. Seeds from three lots were used: one from the NS 7209 IPRO cultivar and two from the 8473 RSF cultivar, produced in the states of Goiás and Mato Grosso, Brazil. Each lot was manually segregated into three portions: the original lot (OL), seeds with an intact seed coat (IS), and seeds with a cracked seed coat (CS), which were stored at temperatures of 15 °C and 28 °C for 270 days. The experiment was carried out in a completely randomized design. Vigor and viability were evaluated using the tetrazolium test, first germination count, germination test, accelerated aging, and electrical conductivity at 0, 45, 90, 135, 180, 225, and 270 days of storage, as well as seedling emergence in a seedbed after 0, 90, 180, and 270 days of storage. Seed coat cracking in soybean reduced the physiological quality of the lots in all the tests compared to seeds with intact seed coats, and this effect was more pronounced when seeds were stored at 28 °C. Seed coat cracking contributes to increased seed deterioration in soybean when seeds are stored under high-temperature conditions.
From “pipes” to operators: a new social existence in the factory under workers` management
Authors: Takahashi Mara Alice Batista Conti , Mandl Alexandre Tortorella
Published: November 2024

Abstract Introduction this essay deals with the changes in the subjective sphere of a segment of the working class, in their experience of self-management at Flaskô, the longest-running factory under workers’ control in Brazil. Objective to analyze the perspective of workers’ subjectivity as protagonists and arrangers of a real utopia of work transformation. Methods the essay approach is based in oral history methodology, focused on the social construction of the memory of its actors, based on the testimonies and life stories of four workers. Results a new way of producing, made possible by the democratization of the social relations of production, has led to an increment in the professional genre and an increase in workers’ power to act, as the main factor in human self-realization, preservation of the quality of work, and workers’ health. Conclusion the Flaskô experience was a powerful articulation of anti-capitalist strategies, within the order, which, by aiming to maintain jobs through the nationalization of the factory under workers’ management, transformed the destructive elements of capitalist management modes that kill and sicken workers, enabling a new form of social existence for its workers, through the democratization of the social relations of production.
A Model of Human Occupation-based intervention for individuals with Obsessive-Compulsive Disorder: two case reports
Authors: Turk Zehra Yeniceli , Turan Zeynep Celik , Abaoglu Hatice
Published: November 2024

Abstract Introduction Preliminary occupational therapy intervention studies are much needed. Although the importance of Obsessive Compulsive Disorder (OCD) recognized as highly restrictive for individuals, there are only e few studies addressing occupational therapy interventions for them. Objectives This study aimed to examine the effectiveness of a person-centered, holistic occupational therapy assessment and interventions using the conceptual model of practice, the Model of Human Occupation (MOHO), for persons diagnosed with OCD. Method A demographic information form, Occupational Self-Assessment (OSA), Model of Human Occupation Screening Tool (MOHOST), and a semi-structured interview form were employed pre and post-intervention. The Pittsburgh Sleep Quality Index was also used for Case 2. Results After 16 sessions, the findings showed positive results of the person-centered occupational therapy intervention on occupational participation and performance in both cases. Conclusion This study highlights the effectiveness of occupational therapy intervention on occupational participation and performance, based on the MOHO approach for two cases of individuals with OCD.