bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Microplastics on Global Public Health: A Systematic Review and Meta-Analysis
Authors: Adamopoulos Ioannis , Valamontes Antonios
Published: February 2025

Background: Microplastics (MP(s)) are an emerging environmental contaminant with growing concerns about their potential impact on human health. These particles, measuring less than 5 mm, are pervasive in the environment and have been detected in food, water, air, and human biological tissues. Despite increasing awareness, limited studies explore MP(s) exposure and its health risks. Research remains sparse on the breakdown of larger plastic fragments in biological systems and their long-term effects. Standardized exposure assessment methods, harmonized effect size reporting, and regulatory interventions are urgently needed. Methods: This systematic review and meta-analysis synthesize current evidence on human MP(s) exposure pathways, associated health risks, and knowledge gaps. Following PRISMA 2020 guidelines, we systematically searched multiple databases, including PubMed, Scopus, Web of Science, Embase, and Cochrane CENTRAL, to assess the extent of MP(s) exposure and its possible health implications. Results: Findings suggest widespread exposure through ingestion of food and water contamination, inhalation of airborne MP(s), and potential dermal absorption. Toxicological studies in animal models indicate that MP(s) can induce oxidative stress, metabolic dysfunction, immune dysregulation, and endocrine disruption. However, direct human health effects remain unclear due to methodological limitations, variability in exposure assessment, and a lack of long-term studies. Emerging research highlights concerns regarding neurological toxicity, reproductive health effects, and atmospheric transport mechanisms. Conclusions: The study analyzes the impact of MP(s) on public health, emphasizing the necessity for regulation and methods to limit its effects on ecosystems and humans. The findings highlight the importance of developing uniform guidelines for healthy persons, given the diversity in reported studies and the lack of existing guidelines. This global issue needs immediate action. Future research should prioritize longitudinal human studies, improved plastic detection techniques, and risk characterization frameworks to understand the public health implications of plastic exposure.
Advances in Nanotechnology-Based Biosensors for Disease Diagnosis
Authors: Karanikola Aikaterini-Eleftheria , Charistou Maria , Zarketan Despoina , Oikonomou Eleni , Charalampopoulou Eleftheria , Spyratou Ellas , Efstathopoulos Efstathios P
Published: February 2025

The foundation of human medicine and therapeutics lies in accurate and prompt diagnosis of the underlying cause of malaise. Biosensors have proven invaluable when incorporated in clinical practice. In recent years, the embodiment of nanomaterials in biosensors has shown promising results and improved sensitivity and specificity for the diagnosis of major causes of morbidity and mortality, such as cancer, cardiovascular and infectious diseases. Metal-based nanoparticles, carbon nanotubes and quantum dots are some of the most commonly used materials in the manufacturing of biosensors. In this review, the main biosensing methods, such as electrochemical, optical and piezoelectric, are presented. Furthermore, both established and emerging trends in biosensing methods for quick, reliable and safe disease diagnosis are being explored. Finally, future perspectives for point-of-care sensing systems and the development of biosensors for novel biomarkers are discussed.
Adaptive Cluster-Based Normalization for Robust TOPSIS in Multicriteria Decision-Making
Authors: Anes Vitor , Abreu António
Published: February 2025

In multicriteria decision-making (MCDM), methods like TOPSIS play a critical role in evaluating and comparing alternatives across multiple criteria. However, traditional normalization techniques often fall short when faced with data that includes outliers, large variances, or diverse measurement units, leading to rankings that may be skewed or biased. To address these challenges, this paper introduces an adaptive cluster-based normalization approach, applied to a real-world case study of selecting a city to host an international event. The method works by grouping alternatives into clusters based on their similarities in criterion values and applying tailored normalization within each group. This localized approach reduces the impact of outliers and ensures that scaling adjustments are aligned with the unique characteristics of each cluster. When tested in the case study, where cities were evaluated based on cost, infrastructure, safety, and accessibility, the cluster-based normalization method provided more stable and balanced rankings, even in the presence of significant data variability. By improving fairness and adaptability, this approach strengthens TOPSIS’s ability to deliver accurate, context-aware decisions, making it an invaluable tool for tackling complex datasets in real-world applications.
Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype
Authors: Maher Patrick , Guzman Emilia , Chaffin Joanna , Kashif Reema , Burnside Rachel D.
Published: February 2025

Background/Objective

Epstein-Barr Virus (EBV) infection can be associated with lymphocytic hematological malignancies, including Systemic Epstein-Barr Virus-Positive T-Cell Lymphoma of Childhood (SEBVTCL). A common complication of EBV infection, hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of immune activation that is present in virtually all cases of SEBVTCL, which requires urgent treatment as this malignancy can be rapidly fatal. Abnormal karyotypes have been strongly associated with SEBVTCL as a distinguishing feature from HLH in the literature. Here, we discuss the diagnostic challenges and social complications in a case of an unaccompanied minor immigrant patient with a highly complex karyotype diagnosed with SEBVTCL with associated HLH.

Methods

Laboratory testing confirmed the presence of EBV+ HLH and cytogenetic analysis was performed to investigate a neoplastic process in this patient, confirming SEBVTCL. Chromosomal microarray (CMA) was performed to try to clarify the complex findings by chromosome analysis but demonstrated normal results.

Results:

Chromosome analysis demonstrated a highly complex hypertriploid clone that confirmed a diagnosis SEBVTCL. After declining treatment, the patient was discharged to his guardian against medical advice and succumbed to his disease shortly after.

Conclusions:

SEBVTCL can be challenging to diagnose due to the similarity in clinical and pathological presentations. In virtually all cases reported in the literature, an abnormal karyotype has been reported to be the most important prognostic factor. We proposed that in cases with diagnostic ambiguity, an abnormal karyotype can help favor SEBVTCL over EBV+ HLH.
Fragile Peace, Handle With Care: Revisiting Character Education and Ethnic Relations in Post-Conflict Sambas Regency, Indonesia
Authors: Kurniawan Syamsul , Miftah Muhammad , Taufik Egi Tanadi
Published: February 2025

This qualitative research examined the challenges of the character education for Malay-speaking Muslim children in Sambas Regency, Indonesia, a post-conflict region marked by inter-ethnic tensions. Based on observation, interviews, and literature review, the discussion explored the impact of prolonged ethnic conflict on the education system, character building, and transitional peacemaking. Schools in Sambas faced significant challenges in integrating peace and multicultural education into teaching practices. The discussion illustrated how institutional character education fosters multiculturalism and peace by addressing the residual effects of conflict while aligning with government regulations and local wisdom. It argued that while character education is a long-term effort, it held promise for fostering sustainable positive peace and inter-ethnic harmony. The insights from Sambas offered a framework for character education in similar conflict-affected regions, emphasize the importance of peace and multicultural values in education.
Integration of Multimedia in Toddlers’ Education of the Al-Qur’an: A Case of Kampong Gunong Qur’anic House Belitung
Authors: Febrino Febrino , Karyono Karyono , In’ami Moh
Published: February 2025

This study explores the use of multimedia in teaching the Al-Qur'an to toddlers at the Kampong Gunong Qur'anic House in Belitung. Using a qualitative case study approach, data were gathered through interviews, observations, and documents. The findings highlight the effective use of multimedia tools, particularly Syaikh Kamil El Laboudy’s murattal video, in the Tabarak method of Al-Qur'an learning. This approach successfully motivated toddlers to memorize the Al-Qur'an quickly while improving the quality of their recitation. However, the study's limitations included its focus on a single institution and the short duration of the research, which did not examine long-term effects on childhood’s cognitive and spiritual development. Despite these limitations, the study contributed valuable insights into integrating technology in early children's religious education and offered recommendations for future research on the long-term impacts of multimedia-assisted Al-Qur'an learning.
Religious Moderation Education Model in Islamic Boarding Schools Based on the Teachings and Strategies of the Walisongo's Da'wah
Authors: Ihsan Ihsan , Khafidzin Zaenal , Zuhri Achmad
Published: February 2025

This article aims to analyze the model of religious moderation education in Islamic boarding schools, focusing on the implementation of Walisongo's da'wah teachings and strategies. The development of Walisongo's da'wah teachings and strategies is essential for reinforcing religious moderation in Islamic boarding schools, thereby serving as a model for religious moderation education. This study falls under the category of qualitative descriptive research. The phenomenological approach was employed to investigate the implementation of Walisongo's da'wah teachings and strategies in religious moderation education within Islamic boarding schools thoroughly and comprehensively. This study was carried out in Central Java Province, utilizing purposive sampling to select participants from Al-Hidayat Lasem Islamic Boarding School, Qudsiyyah Kudus Islamic Boarding School, Futuhiyyah Demak Islamic Boarding School, Annawawi Purworejo Islamic Boarding School, and Al-Hikmah Benda Sirampog Brebes Islamic Boarding School. The research data were collected through documentation, observation, and interviews, followed by qualitative descriptive analysis. The study's findings indicate that the teachings and strategies of Walisongo's da'wah, as adopted by Islamic boarding schools in Central Java, encompass the preservation of local wisdom, opposition to fanaticism, promotion of economic independence, nationalism, broad insight, and community protection. The Islamic boarding school curriculum includes teachings, instructional materials, examples set by Kiai, and the prevailing culture, which collectively fosters student behaviors characterized by tolerance, respect for ulama, historical awareness, trustworthiness, knowledge development, commitment to state principles, and open-mindedness.
Microscopic, Stereological, and Biochemical Investigation of the Effects of Vitamin B12 on Vascular Changes in an Experimental Subarachnoid Hemorrhage Model in Rats
Authors: Yücel Murat , Çetin Eyüp , Demirtaş Cumaali , Sönmez Cansu , Güler Eray Metin , Beyaztaş Hakan
Published: February 2025

Background
Spontaneous subarachnoid hemorrhage (SAH) is a severe neurological condition with significant morbidity and mortality. Cerebral vasospasm, a common complication of SAH, is a leading cause of delayed ischemic injury. Oxidative stress and inflammation are central to the pathophysiology of vasospasm. Vitamin B12, a water-soluble vitamin with antioxidant and anti-inflammatory properties, has shown potential neuroprotective effects in experimental models.
Objectives
This study aimed to investigate the effects of vitamin B12 on vascular changes, oxidative stress, and inflammatory markers in an experimental rat model of SAH.
Methods
Eighteen Sprague Dawley rats were divided into three groups: a control group, an SAH group, and an SAH + B12 group. SAH was induced by injecting autologous blood into the cisterna magna. The SAH + B12 group received intraperitoneal vitamin B12 (15 mcg/kg) at 1 and 24 hours post-SAH. Biochemical parameters, including total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and inflammatory cytokines (IL-1β, IL-6, TNF-α), were analyzed. Histopathological evaluation of the basilar artery was performed, measuring arterial diameter and wall thickness.
Results
The SAH group exhibited significant elevations in TOS, OSI, IL-1β, IL-6, and TNF-α levels, along with decreased TAS, indicating heightened oxidative stress and inflammation. The SAH + B12 group showed significant reductions in TOS, OSI, and inflammatory cytokines compared to the SAH group (p < 0.05), alongside improved TAS levels. Histopathological findings demonstrated reduced arterial wall thickening and preserved lumen diameter in the SAH + B12 group compared to the untreated SAH group.
Conclusion
Although the differences in arterial diameter and wall thickness were not statistically significant, the findings suggest that vitamin B12 may mitigate SAH-induced vascular injury by reducing oxidative stress and inflammation. These results highlight the potential of vitamin B12 as a therapeutic agent for SAH-related vasospasm. Further studies are needed to validate these findings in larger populations and clinical settings.
Treatment Efficacy and Lung Abnormalities of Amikacin Liposome Inhalation Suspension for Refractory Mycobacterium avium Complex Pulmonary Disease: A Two-Center Retrospective Cohort Study
Authors: Tokita Nozomi , Ito Masashi , Urabe Naohisa , Fujiwara Keiji , Furuuchi Koji , Kodama Tatsuya , Ohe Takashi , Kurosaki Atsuko , Tanaka Yoshiaki , Yoshiyama Takashi , Kishi Kazuma , Ohta Ken , Morimoto Kozo
Published: February 2025

Background: The guideline recommends the addition of amikacin liposome inhalation suspension (ALIS) to guideline-based therapy for patients with refractory Mycobacterium avium complex pulmonary disease (MAC-PD). The real-world data on the treatment efficacy and safety of ALIS remain insufficient.
Research Question: What factors influence culture conversion during treatment with ALIS, and what are the best practices for managing ALIS-related adverse events, particularly ALIS-related lung abnormalities (ALIS-RLA)?
Study Design and Methods: This was a two-center retrospective cohort study involving 87 patients with refractory MAC-PD who received ALIS from August 2021 to September 2023. On the basis of data obtained from medical records, adverse events were assessed in 76 patients, whereas treatment efficacy was evaluated in 49 patients.
Results: The overall sputum culture conversion rate was 28.6%. However, among patients without cavities, it was significantly higher at 64.7%. Prognostic factors associated with culture conversion included a greater body mass index (19.5 kg/m2 vs. 17.2 kg/m2, p=0.010), a lower rate of prior aminoglycoside administration (50.0% vs. 91.4%, p=0.003), a lower rate of cavity formation (21.4% vs. 82.9%, p<0.001), and a lower radiological severity, as calculated by the NICE scoring system (7.0 vs. 14.0, p=0.006).
The most frequent adverse event was dysphonia, which occurred in 53.9% of the patients. Newly developed ALIS-RLA were observed in 82.1% of patients who underwent chest computed tomography (67 patients): 53 patients (79.1%) had multiple nodular patterns, 18 patients (26.9%) had the organizing pneumonia pattern, one patient (1.5%) had the diffuse alveolar pattern and another (1.5%) had the hypersensitivity pneumonitis pattern. Among patients with ALIS-RLA, 92.7% were asymptomatic, and 85.5% were able to continue ALIS.
Interpretation: Introducing ALIS at an early stage is crucial for preventing the progression of MAC-PD. Although ALIS-RLA were observed in 82.1% of patients, discontinuation of ALIS appeared unnecessary in asymptomatic cases of ALIS-RLA.
Global trends of Neck pain, 1990-2019, and trends prediction: studied from the Global Burden of Disease Study 2019
Authors: Song Junjie , Li Jianming , Sun Shengtao , Liu Jianyu
Published: February 2025

Background
Neck pain is a disease of the musculoskeletal system caused by various factors, which has a high incidence, morbidity, and disease burden. Based on data from the Global Burden of Disease Study (GBD) 2019, the authors analyzed the incidence, prevalence, and rates of DALYs for neck pain at the gender, age, and sociodemographic index levels, respectively, to explore the epidemiological characteristics and disease burden of neck pain.
Methods
The Joinpoint regression model was used to analyze the 30-year prevalence trend of neck pain. The Autoregressive Integrated Moving Average (ARIMA) is used to predict future trends in neck pain.
Results
In 2019, the global age-standardized incidence rate, age-standardized prevalence rate, and age-standardized DALYs rate per 100,000 population were 579.09 (95% uncertainty interval 457.90 to 729.64), 2696.52(95% UI 2177.01 to 3375.19), and 267.35(95% UI 175.53 to 383.54), respectively. Countries with high sociodemographic indexes have high prevalence trends, and the Low SDI countries had the lowest disease burden of neck pain. The predicted incidence in 2026 is 609.85 per 100,000 population.
Conclusions
In summary, the prevalence of neck pain and the burden of the disease have increased over the past 30 years, especially since 2011, with the incidence increasing year by year in high-SDI countries. The overall prevalence is higher in women than in men. There is a trend toward younger people.
Influence of Therapeutic Adherence, Patient-Therapist Alliance, and Patient-Centred Rehabilitation Approach in Subacute Stroke Rehabilitation: Protocol for a Prospective Observational Study.
Authors: Arranz-Escudero Adrián , Ortiz-Gutiérrez Rosa , Carpio-Calatayud Ester , Díaz-Arribas María J , Cano-de-la-Cuerda Roberto , Martín-Casas Patricia
Published: February 2025

Introduction. Adherence to guidelines and recommendations during rehabilitation is frequently demonstrated to be poor in stroke patients, which may impede their progress. Although several clinical risk factors have been explored to explain this phenomenon, personal factors remain underexamined in the literature. The present study aims to investigate the impact of therapeutic adherence, therapeutic alliance, and patient-centred perception on rehabilitation outcomes in stroke patients.
Methods and analysis. An observational study comprising two phases will be conducted at a neurorehabilitation hospital in Madrid, Spain. In the first phase, the content of the Scale of Adherence to Treatment of Physiotherapy (AdT-Physio) and the Therapeutic Alliance in Physiotherapy Questionnaire (CAF-P) will be adapted for the stroke population using the Delphi method to achieve consensus among at least 15 experts nationwide. Following this, a pilot study will be conducted to evaluate the comprehensibility of the adapted questionnaires. In the second phase, a content validation and correlation study of these questionnaires will be conducted through a prospective longitudinal observational study with multiple measurement points. Stroke patients aged over 18 years, in the subacute stage, and undergoing neurorehabilitation programmes will be included. Sociodemographic and clinical data will be collected at baseline, while physical capacities (assessed through trunk control, balance, and gait performance scales) will be evaluated throughout the rehabilitation process and at discharge. The target sample size is set at n=59, accounting for a 20% dropout rate. A comprehensive psychometric analysis will be performed, including the examination of convergent and criterion validity through correlations with relevant measures. Reliability will be assessed using Cronbach's alpha and test-retest correlation coefficients, and mean differences will be analysed using analysis of variance (ANOVA).
Ethics and dissemination. The present study has been granted ethical approval by the Ethics Committee of the Hospital Universitario Clínico San Carlos (Madrid, Spain), with the reference number 23/438. Prior to participation, all subjects will be required to provide written informed consent. The findings will be disseminated through publication in a peer-reviewed scientific journal.
Postgraduate Theses on Coaching Practice in Special Education: A Systematic Review Study
Authors: Alp Zekai Alper , Aksoy Veysel , Yetkin Ahmet İlkhan
Published: February 2025

Introduction: The importance of evidence-based practices in special education has been a focal point for the field. Ensuring the implementation of evidence-based interventions with high reliability and the effective results in special education have revealed the importance of programs aimed at increasing the competencies of individuals providing interventions and coaching have become widespread. Coaching practices, which is considered a new area for special education, has not yet been determined creates conceptual confusion.
Method: In this systematic review study, it was aimed to examine descriptively and methodologically the theses involving coaching practices with individuals with special needs and to provide a conceptual framework for coaching practices. In this context, twenty theses, fifteen of which were doctoral theses and five master's theses, were examined in the database of the National Thesis Center of the Council of Higher Education (YÖKTEZ), including the year of production, participants, type of coaching, setting, dependent and independent variables, effectiveness data for acquisition, monitoring and generalization, application, inter-observer reliability and social validity data regarding their reliability and validity.
Findings: The findings obtained from the study show that the training programs offered to parents, teachers and siblings, which include side-by-side, distance and hybrid coaching practices, are effective in helping individuals with autism spectrum disorder (ASD), intellectual disability, specific learning disability and multiple disabilities to acquire skills, and in helping parents, teachers and typically developing siblings to maintain and generalize the skills acquired by individuals with special needs. In all the theses examined, it is seen that social validity data were collected in addition to intervention and inter-observer reliability data.
Discussion: The findings of the thesis studies included in the review were discussed with the findings of other studies examining coaching practices in the field of special education in the literature and suggestions were made for the future.
Pengaruh Faktor Internal Dan Eksternal Terhadap Harga Saham
Authors: Sondakh Michael Krisnaputra , Sumiati Sumiati
Published: February 2025

The purpose of this study is to analyze the effects of internal factors consisting of Return on Assets (ROA) and Price-to-Earnings Ratio (PER) and external factors consisting of global coal price and global gas and oil price on the stock price movement of coal mining companies listed on the Indonesia Stock Exchange during the 2018-2022 period. This quantitative research examines eight coal mining companies listed on the IDX in the 2018- 2022 period, which were selected using simple random sampling technique with several criteria. The results of the data analysis performed in SPSS 22 indicate that Return on Asse (ROA) and Price-to-Earnings Ratio (PER) have positive and significant effects on the stock price movement of the coal mining companies. Further, global coal price has no significant effect, while global oil and gas price has positive and significant effect on the said price movement.
 
Abstrak
Penelitian ini memiliki tujuan untuk menganalisis pengaruh faktor internal yaitu Return On Asset (ROA) serta Price to Earning Ratio (PER) dan faktor eksternal yaitu Harga batubara global serta harga minyak bumi dan gas global terhadap pergerakan harga saham perusahaan pertambangan batubara yang terdaftar dalam Bursa Efek Indonesia (BEI) pada periode 2018-2022. Jenis penelitian ini adalah kuantitatif dengan menguji 8 perusahaan pertambangan batubara dalam BEI periode 2018-2022. Sampel diambil sesuai dengan kriteria yang digunakan dengan metode Simple Random Sampling lalu dianalisis dengan metode analisis regresi berganda menggunakan SPSS 22. Hasil dari penelitian menunjukkan Return On Asset (ROA) serta Price to Earning Ratio (PER) berpengaruh positif dan signifikan, Harga batubara global tidak berpengaruh signifikan serta harga minyak bumi dan gas global berpengaruh positif dan tidak signifikan terhadap pergerakan saham perusahaan pertambangan batubara.
Creating a Proletarian Avant-Garde: Changing Strategies of Journal Editors Returning to Hungary after Emigrating to Western Europe
Authors: Dobo Gabor
Published: February 2025

Research on European avant-garde periodicals often highlights their role in a transnational network characterized by non-hierarchical knowledge production.However, this perspective faces a challenge when examined in the context of East Central Europe. For example, studies reveal that journal editors returning from Western European emigration to Hungary between the two world wars, by departing from the cultural milieu of the core countries, found themselves excluded from transnational circulation. In contrast to both global and local analyses, my focus is on reinterpreting the history of Hungarian avant-garde periodicals between 1925 and 1928 as an adaptation to local circumstances. Specifically, I aim to explore the modes of production and ideologies available to avant-garde editors, notably Lajos Kassák and Aladár Tamás, who returned from Western Europe to reintegrate their journals into the Hungarian-speaking communities of the successor states of the Austro-Hungarian Monarchy. Drawing on extensive archival sources, I trace the transformation of avant-garde journals, once integral to the transnational network, shifting their focus from a middle-class readership and/or an audience composed by fellow avant-garde editors to increasingly engage with local working-class readers. The central point of examination is the journal 365, edited in both Vienna and Budapest. Furthermore, I undertake an analysis of closely affiliated companion journals, including Ma [Today], Dokumentum, Uj Föld [New World/New Ground], 100%, and Munka [Work/Labour].
A Century of Scripting through German Children’s Periodicals
Authors: Van de Wiele Eva
Published: February 2025

Relying on Robin Bernstein’s field-changing analysis of historical objects as ‘scriptive things’, this article considers ‘movable sections’ of German children’s periodicals to chart the evolution of pedagogical paradigms and gendered ideas between 1850 and 1950. More specifically, I consider needlework for girls and construction sections aimed at boys through a historical lens. These movable sections, along with the scribbles left on them, foreground a legacy of interactive and gendered inculcation and offer childhood scholars clues to ground these ‘movable sections’ in their wider media and educational environment.
Exploring Social Media Use Among Medical Students Applying for Residency Training: Cross-Sectional Survey Study
Authors: Jandu Simi , Carey Jennifer L
Published: February 2025

Background

Since the COVID-19 pandemic, residency candidates have moved from attending traditional in-person interviews to virtual interviews with residency training programs. This transition spurred increased social media engagement by residency candidates, in an effort to learn about prospective programs, and by residency programs, to improve recruitment efforts. There is a paucity of literature on the effectiveness of social media outreach and its impact on candidates’ perceptions of residency programs.

Objective

We aimed to determine patterns of social media platform usage among prospective residency candidates and social media’s influence on students’ perceptions of residency programs.

Methods

A cross-sectional survey was administered anonymously to fourth-year medical students who successfully matched to a residency training program at a single institution in 2023. These data were analyzed using descriptive statistics, as well as thematic analysis for open-ended questions.

Results

Of the 148 eligible participants, 69 (46.6%) responded to the survey, of whom 45 (65.2%) used social media. Widely used social media platforms were Instagram (19/40, 47.5%) and Reddit (18/40, 45%). Social media influenced 47.6% (20/42) of respondents’ opinions of programs and had a moderate or major effect on 26.2% (11/42) of respondents’ decisions on program ranking. Resident-faculty relations and social events showcasing camaraderie and wellness were the most desired content.

Conclusions

Social media is used by the majority of residency candidates during the residency application process and influences residency program ranking. This highlights the importance of residency programs in leveraging social media usage to recruit applicants and provide information that allows the candidate to better understand the program.
Implementation of a centralized health quarantine information system at the Pangkalpinang Port Health Office
Authors: Pratama Fikry , Ahmad Riris Andono , Sanjaya Guardian Yoki
Published: February 2025

Purpose: This research aims to evaluate and analyze the factors affecting the implementation the health quarantine information system (SINKARKES) in KKP Pangkalpinang.
Methods: Quantitative research with cross-sectional design research. The population studied several 65 respondents. Test statistical and data analysis using structural equation model Partial least-square with smartpls 3.0 software.
Results: Five factors have significant effects in supporting the success of the implementation of SINKARKES, the quality of the system to the user satisfaction, the quality of information on user satisfaction, the quality of service to user satisfaction, the use of systems against net benefit and management support of net benefit.
Conclusions: The implementation of SINKARKES uses a top-down approach with the development and adjustment of a system that runs thoroughly by focusing on meeting the needs of the central unit. This approach model is considered not ideal for the characteristics of the complex health quarantine information system module.
Improving the SRAM Layout Design using Cadence Virtuoso
Authors: R N Nandhini
Published: February 2025

The explosive growth in semiconductor technology has fuelled the need for high-speed, low-power, and small form
factor memory solutions, and Static Random Access Memory (SRAM) is an indispensable part of contemporary integrated
circuits. The conventional SRAM structures are beset with formidable power consumption, area, and stability trade-offs at
different Process, Voltage, and Temperature (PVT) conditions. This paper introduces an optimized method for SRAM layout
design with Cadence Virtuoso for 6T, 7T, 8T, and 10T SRAM cells to improve their performance in power-constrained and highspeed applications.
The methodology uses layout optimization methods like transistor sizing, W/H ratio tuning, and power-conscious circuit design
to obtain a balanced trade-off between read/write stability, leakage power minimization, and access speed enhancement. Detailed
simulations are performed with varying PVT to analyse the effects of such variations on energy efficiency, area saving, and
reliability. The results show that there is substantial improvement in the cell stability and power consumption and the optimized
structures are suitable for next-generation high-performance and low-power computing devices.
Service Quality of Selected Indian Companies in the Post-Acquisition Period: A Study of the E-Commerce Sector
Authors: Chaudhuri Arpita Sil
Published: February 2025

Mergers and acquisitions (M&A) represent key strategies for corporate restructuring, aimed at achieving growth,
sustaining competition, and generating synergy. As an essential component of business strategy, M&A has gained significant
popularity among corporations and is widely utilized as a restructuring tool. In India, several sectors have actively engaged in
M&A transactions in recent years, with the E-commerce sector standing out due to its rapid expansion. The Indian e-commerce
industry has experienced remarkable growth over the past few years, driven by increased smartphone penetration, rising demand
for international consumer products, and enhanced digital infrastructure. Additionally, the COVID-19 pandemic and
subsequent lockdowns led to a surge in online purchases of essential goods. Recognizing the sector’s potential, the Government
of India has permitted 100% Foreign Direct Investment (FDI) in online retail to encourage new entrants and foster industry
growth. Mergers and acquisitions often respond to technological advancements or evolving market dynamics, necessitating
strategic shifts. In the dynamic e-commerce landscape, service quality and customer satisfaction play a crucial role in shaping
consumer purchase intentions. Maintaining high service standards is essential for businesses to build a sustainable competitive
advantage and ensure customer retention. Any transformation in the industry directly impacts consumers—either positively or
negatively—depending on market conditions and corporate decisions. Therefore, strategic planning should prioritize customer
interests to maintain trust and business continuity. This research focuses on evaluating service quality and customer satisfaction
in selected Indian e-commerce companies during the post-acquisition period, analyzing the implications of M&A on customer
experiences
The Gig Economy Revolution: Evaluating Income Streams and Economic Contributions in Malaysia
Authors: Ahamad Nawawi Nurul Hidayah , Ramli Rosiati , Khalid Norlin , Abdul Rashid Siti Fatimah
Published: February 2025

There has been scant research about the gig economy revolution in Malaysia. Evaluating the exponential growth of the Malaysian gig economy is difficult as there is a lack of dependable data on digital platform revenues. This study fills this gap by examining administrative data from the principal agency propelling Malaysia's digital economy. Between 2016 and 2021, the proliferation of gig workers and digital platforms markedly increased, offering stable incomes and augmenting Malaysia's economic revenue. Significantly, earnings from digital gig employment have surpassed conventional physical gig employment. The growth of local digital platforms during the pandemic of COVID-19 is driven by an increased demand for online services. Regulatory oversight is crucial for safeguarding gig workers and ensuring fair income distribution within this sector.
A Systematic Review of the Challenges and Opportunities of the Agriculture Economic Sector in Malaysia
Authors: Shariff Sharina , Baharudin Siti ‘Aisyah , Ismail Nor Asmat
Published: February 2025

Globalization brings the emergence of technology which has dramatically changed the traditional nature of the agriculture sector into a modern which currently achieves sustainability to address issues of food security, aging and unemployment in most agriculture sectors of the world countries. Particularly, Malaysia's agriculture sector faces challenges, including a labor shortage due to its domination by aging farmers, and low youth participation due to negative agricultural perspectives.  Nevertheless, this sector remains crucial and looking forward to sustainability as world population growth is the challenge of agriculture found among Malaysian researchers. Another hand, several themes of opportunities have been found that had been expected to respond to the current agriculture challenges trends such as youth, modern agriculture and agricultural entrepreneurship which have been often discussed in the literature.  Agriculture Entrepreneurship and emerging trends of technology changes have raised the attention to be integrated to respond and create an opportunity for the group of youth to respond through their agriculture sector participation which had been often discussed among previous researchers.  Youth are identified as the key to productivity capability and inclusive development as aligned to the establishment of the youth agropreneur unit in 2013 which aims to groom a new breed of youth Agropreneur in Malaysia under Malaysia National Agriculture Policy 2030.  Therefore, the purpose of the study is to review past studies and to analyze the pattern of the challenges and opportunities of the agriculture sector in Malaysia.
The Interplay between Risk Management and Internal Control Towards Corporate Tax Aggressiveness
Authors: Muhmad Siti Nasuha , Mohd Nasir Noor Emilina , Muhmad Siti Nurain , Rashid Norfadzilah
Published: February 2025

Corporate tax aggressiveness has become a major issue in the international business environment as they exploit the loopholes of legitimate tax avoidance. Although these techniques have the potential to increase revenues, they are viewed critically by regulators and society. Due to the reputational and financial impact associated with aggressive tax planning, effective measures are required to manage the risks and ensure compliance with tax laws. In addressing the issue of corporate tax aggressiveness, this paper examines the role played by risk management and the effectiveness of internal controls. Based on agency theory, tax aggressiveness often represents an agency problem between agent and principal. Therefore, effective risk management provides a systematic approach to recognizing and mitigating the potential pitfalls of aggressive tax strategies, while robust internal controls ensure compliance and align tax practices with governance standards. This study underscores the critical need for companies to view tax aggressiveness not just as a financial strategy, but as a governance challenge that requires robust risk mitigation and control systems. Although it can bring financial benefits and competitive advantages, it also carries financial, reputational and regulatory risks that jeopardize long-term value. Hence, companies should pursue a balanced approach to tax planning that harmonizes profitability targets with social expectations and regulatory standards.
Metabolic dysfunction associated with alterations in gut microbiota in adolescents with obesity
Authors: Xie Quin Yuhui , Granato Alessandra , Wong Anthony , Yau Christopher , Noseworthy Rebecca , Chen Tina , Gianetto-Hill Connor , Allen-Vercoe Emma , Guidos Cynthia J. , Hamilton Jill K. , Danska Jayne S.
Published: February 2025

Obesity in childhood is associated with adulthood obesity, type 2 diabetes (T2D), and future metabolic complications. The gut microbiome is a modifier of host metabolic function with altered bacterial composition associated with disease risk. Few studies have investigated the relationships between metabolic disease, inflammation and the gut microbiota in youth where these connections likely originate. Here we characterized the gut microbiome of a cohort of 56 non-diabetic adolescents with obesity using fecal DNA sequencing with absolute bacterial quantitation together with immune and metabolic profiling. We observed multi-log order variation in absolute bacterial biomass dependent on host environment and associated with bacterial taxonomic composition based on a nested case-control comparison. Participants with higher biomass displayed a healthier phenotype with higher gut microbiome diversity, lower abundance of taxa associated with inflammation and pathogenicity such as Escherichia Coli, and lower levels of neutrophil activities. Further association analysis revealed sex-dependent variation, with higher levels of insulin resistance, fasting triglycerides, and markers of neutrophil activities in male adolescents with lower bacterial biomass. Together these results suggest that intestinal bacterial biomass and composition are associated with metabolic and inflammatory dysregulation evident before T2D diagnosis and identify sex differences in microbiome-associated metabolic dysfunction in adolescents with obesity.
Peran Hedging dalam Membangun Citra Positif dalam Pidato Presiden AS
Authors: Suswati Rita , Pratiwi Dinda Khairani , Manullang Jessica Paskah Elizabeth , Nailah Nailah
Published: February 2025

Hedging merupakan strategi retorika yang penting dalam wacana politik, digunakan untuk menunjukkan derajat keyakinan dan membangun citra positif pemimpin, khususnya dalam pidato Presiden AS (1993-2021). Tujuan penelitian ini adalah untuk menganalisis peran hedging dalam membangun citra positif dan memahami variasi penggunaannya berdasarkan konteks politik dan audiens. Metode yang digunakan adalah studi pustaka kualitatif, dengan analisis data sekunder berupa transkrip pidato dan literatur terkait. Temuan utama menunjukkan bahwa penggunaan hedging bervariasi antara presiden, di mana Bill Clinton dan Barack Obama menggunakannya untuk mempertahankan kredibilitas dan memperkuat komitmen, sementara Donald Trump menggunakannya lebih sedikit, tetapi tetap dalam konteks diplomatik. Kesimpulan penelitian menegaskan bahwa hedging memiliki peran penting dalam membangun citra positif pemimpin, namun harus digunakan dengan hati-hati agar tidak disalahartikan sebagai ketidakpastian. Kata kunci: hedging, strategi retorika, wacana politik, citra positif
The Industrialization of Soviet Art Culture in the 1917–1930s
Authors:   N.G. Chernyshevsky Saratov State University, Zhumaev Roman A.
Published: February 2025

The aim of the article is an attempt to identify the features of the industrial approach to art in early Soviet cultur-al policy. The article analyzes the technical vocabulary in the language of Soviet power in the first decades of the 20th century, examines the sectoral approach to the management of artistic culture in the early USSR, in-cluding centralization, unification and planning of cultural production. As one of the markers of the industrial turn in the art of the first post-revolutionary decades, the spread of industrial subjects in the art of the period under consideration is highlighted. The author believes that the changes in the USSR cultural policy associated with the new industrial understanding of art make it possible to use the term “industrialization of artistic culture” in relation to these processes. As a result of this industrial turn in Soviet culture, the Soviet system itself can be considered as a cultural super-industry with centralized management of artistic culture.
Con los tacos en la alfombra. Proceso de investigación y experiencias de campo en el abordaje de elites económicas en la provincia de Córdoba, Argentina, 2015-2019
Authors: Schaigorodsky Emilia
Published: February 2025

El presente artículo tiene por objeto dar cuenta del diseño y proceso de investigación llevado adelante en torno a las sociabilidades con lo político de la elite económica empresarial de la provincia de Córdoba, Argentina, en el período 2015-2019. Reconstruimos el proceso en sus momentos, desde los obstáculos y elementos inesperados que produjeron redefiniciones desde el diseño original. Las principales conclusiones abrevan en la literatura metodológica sobre la investigación en sectores privilegiados, y resaltan las fronteras y asimetría entre los esquemas de percepción y relación personales, y los vínculos identificados en el campo.
PENGARUH PROMOSI KUALITAS PELAYANAN DAN KUALITAS PRODUK TERHADAP LOYALITAS NASABAH DENGAN KEPUASAN NASABAH SEBAGAI VARIABEL MODERATING PADA BANK SYARIAH INDONESIA KCP ENREKANG
Authors: SAHARUDDIN HASRUL , Gani Nuraeni , Gani Ilham
Published: February 2025

The aim of this research is to analyze and find out how much influence promotion of service quality and product quality has on customer loyalty with customer satisfaction as a moderating variable at the Indonesian sharia bank KCP Enrekang. This type of research is quantitative research using a comparative approach which can be interpreted as research that compares one object with another. The sampling technique used was purposive sampling. The results of this research show that promotions do not have a positive and significant effect on customer loyalty, service quality has a positive and significant effect on customer loyalty, product quality has a positive and significant effect on customer loyalty, customer satisfaction is unable to moderate the influence of promotional variables on customer loyalty, customer satisfaction is not able to moderate the influence of service quality variables on customer loyalty, customer satisfaction is able to moderate the influence of product quality variables on customer loyalty.
Efektivitas Penerapan Akad Musyarakah Mutanaqisah (MMQ) Pada Pembiayaan Griya Hasanah Di Bank Syariah Indonesia KCP Makassar Veteran
Authors: Ismatul Husnah  , Samsul  , Kamaruddin
Published: February 2025

Home Ownership Credit Financing (KPR) in Islamic banks has various contract systems, including a sale and purchase contract (Murabahah), Istishna contract and participation (Musyarakah Mutanaqishah). This study aims to determine the effectiveness of the application of the Musyarakah Mutanaqisah contract in Griya Hasanah Financing at Bank Syariah Indonesia KCP Makassar Veteran. This research uses Qualitative research methods. The informants in this study were Branch Managers and Financing Section Employees at Bank Syariah Indonesia KCP Makassar Veteran. The data collection methods used are observation, interview, and documentation. The results showed that the application of the Musyarakah Mutanaqisah (MMQ) contract in financing Home Ownership Credit Products (KPR) / Griya at Bank Syariah Indonesia KCP Makassar Veteran was used for Refinancing, not purchasing a new house. Its application has been said to be effective which is seen by using 5 indicators, namely: Program Success, Target Success, Satisfaction with the Program, Input and Output Levels, and Achievement of Overall Goals.
 
Keywords: Effectiveness, Musyarakah Mutanaqisah, Griya Hasanah Financing.
Perkembangan Pasar Modal terhadap Pertumbuhan Ekonomi Indonesia Tahun 2019-2023
Authors: Putri Diva Carrisa , Amalia As’adi Firda Rizqi , Alfado Chievo Javantara  , Moch Miqdad  , Maryam Bte Badrul Munir
Published: February 2025

Penelitian ini mengeskplorasi peran pasar modal syariah dalam mendukung pertumbuhan ekonomi Indonesia dari tahun 2019 hingga 2023. Pasar modal syariah, termasuk sukuk dan saham syariah, telah memberikan kontribusi penting terhadap Produk Domestik Bruto (PDB) negara. Hasil analisis menunjukkan bahwa pasar modal syariah terus berkembang dalam hal asset dan jumlah investor, yang mencerminkan peningkatan inklusi keuangan dan stabilitas ekonomi. Dengan mengacu pada data dari Otoritas Jasa Keuangan (OJK), penelitian ini menggunakan metode studi kepustakaan dengan analisis deskriptif untuk mengevaluasi kontribusi aset syariah terhadap ekonomi nasional. Kesimpulan penelitian ini menyoroti bahwa perkembangan produk syaruah, regulasi OJK, dan inovasi produk memiliki dampak positif yang signifikan terhadap pertumbuhan ekonomi jangka panjang. Pasar modal syatiah juga memiliki potensi besar untuk mendukung pertumbuhan ekonomi jangka panjang dan inklusi keuangan, dengan harapan bahwa penguatan regulasi dan inovasi akan terus mendorong kontribusi positif bagi perekonomian nasional.