bluuebunny/crossref_metadata_2025 huggingface dataset:
DESENVOLVIMENTO DE ESTRATÉGIAS PEDAGÓGICAS POR MEIO DO PROJETO “OS TRILHOS DO RECOMEÇO PARA O AVANÇO ESTUDANTIL”: UMA EXPERIÊNCIA DA REDE MUNICIPAL DE ENSINO DE CORUMBÁ-MS NO ENFRENTAMENTO À PANDEMIA DA COVID-19
Authors: Silveira Adrielli Rocha , Barbosa Evaldo Neves , Da Costa Fabiane Aparecida Brandão , Rabelo José Augusto Albuquerque , Sambrana Jorge Luiz Samaniego , Ligier Luciana Moreira , De Moura Maria Aparecida Dias , Tasseo Waldir Ortiz
Published: January 2024

O projeto "Os Trilhos do Recomeço para o Avanço Estudantil" foi desenvolvido pela Rede Municipal de Ensino de Corumbá-MS como resposta aos desafios impostos pela pandemia da Covid-19. Diante da necessidade de adaptação ao ensino remoto, a Secretaria Municipal de Educação implementou estratégias como formação virtual de professores, elaboração de atividades online, e busca ativa para mitigar as perdas de aprendizagem. O projeto incluiu a Avaliação de Percurso, análise de dados, e a recomposição da aprendizagem por meio de sequências didáticas e atividades interdisciplinares. Destaca-se a importância da interação entre os componentes curriculares de língua portuguesa e matemática, priorizando o aprimoramento dessas habilidades. O retorno gradual às aulas presenciais, protocolos de biossegurança, e a aplicação do Plano de Estudo Tutorado complementaram as estratégias. O projeto visou promover a formação integral dos estudantes, considerando a saúde emocional e o enfrentamento dos desafios pós-pandemia.
Effect of supplementation of area specific mineral mixture on reproductive performance of the cows
Authors: MOHAPATRA P , SWAIN R K , MISHRA S K , SAHOO G , ROUT K K
Published: January 2024

Sample of feeds and fodders and serum of cows were collected for mineral analysis. An on-farm trial was carried out in which 80 cows having reproductive disorders were allotted to 4 groups with 20 animals — G1 (control); G2 20 an oestrous heifers supplemented with area specific mineral mixture (ASMM) @ 50 g/day/animal (ANH); G3, 20 anoestrous cows supplemented with ASMM @ 50 g/day/animal (ANC); and G4, 20 repeat breeding cows supplemented with ASMM @ 50 g/day/animal (RBC). In cows, the mean serum Ca and P levels were lower while the mean Zn, Cu, Mn and Fe were higher than critical level. At the end of experimental feeding, the body weights, metabolic body weights, dry matter intake per kg metabolic body weight, DCP and TDN intake of the animals did not differ significantly. The overall serum mineral levels and biochemical values increased significantly in supplemented group than in un-supplemented group. The percentage conception was 5, 40, 40 and 35 in G1, G2, G3 and G4 groups, respectively. Services per conception were significantly lower in the mineral supplemented group than control. Similarly the post-partum oestrous was significantly lower in G2 and G3 cows compared to control animals. Thus the reproductive performance improved due to supplementation of area specific mineral mixture.
Preliminary evaluation of papain: its enzymatic characteristics and effects on growth performance and nutrient digestibility in weaned piglets
Authors: LING BAOMING , FENG DINGYUAN , ZUO JIANJUN , ZHANG ZHONGYUE
Published: January 2024

The present study was conducted to investigate the influence of papain (Carica papaya L.) on performance and nutrient digestibility of weaned piglets and to evaluate whether soy protein ingredients supplemented with papain could replace part of high grade animal protein ingredients in weaned piglet feed. The results showed that Km, optimal pH and temperature of papain were 6.6875 mg/mL, 7.0° and 55°C respectively. It had a good stability when either pH ranged from 5.0 to 9.0 or temperature ranged from 4 to 65°C. The addition of papain at 75 mg/kg level significantly increased in vitro crude protein digestibility of soybean meal and piglet feed. Piglets (300; (Pietrain×Duroc)× (Landrace×Yorkshire)) weaned at 21±1 days with an initial body weight (BW) of 5.92±0.47 kg were assigned by BW, sex, and litter according to a randomized complete block design. The animal trial consisted of 5 dietary treatments with 6 replicates/treatment and 0 piglets/replicate. The dietary treatments were positive control (PC), negative control (NC), NC + 50 mg/kg papain, NC + 75 mg/kg papain, and NC +00 mg/kg papain. The results showed that papain significantly decreased diarrhea incidence of piglets fed the diets containing high level of soy-source protein material. There was a linearly improved apparent crude protein digestibility with the increasing dosage of protease. In conclusion, papain supplementation could be considered as an effective solution to break the inclusion limit of soybean source protein ingredients in weaned piglet diet.
Polymorphism of insulin like growth factor binding protein 3 (IGFBP3) partial gene in mithun
Authors: PANIGRAHI MANJIT , KUMAR SUBODH , DEB S M , MITRA ABHIJIT , CHOWDHARY HITU , SHARMA ARJAVA
Published: January 2024

A fragment of 652 bp corresponding to exon–2–3 of IGFBP3 gene was amplified in 90 mithun (Bos frontalis). The PCR- RFLP analysis showed the absence of polymorphism in this fragment with respect to HinfI restriction enzyme and showed only 2 restriction sites, which produced 3 fragments of 314, 206 and 132 bp (AA genotype). Six single nucleotide differences viz. T34C, C164G, T175C, A354G, T599C and G614A existed in mithun sequences when compared to cattle. The neocleotide and amino acid sequence homology between them was 98.2 and 100% respectively. Mithun had minimum deviation from cattle with respect to nucleotide as well as amino acid sequences. The sequence of the amplicon, which was the first report on mithun IGFBP3, was submitted to GenBank (Accession number EF686017).
Hill cattle of Pithoragarh district of Uttarakhand
Authors: PUNDIR R K , SINGH P K , SHARMA D , SAINI A , SINGH C V , PRAKASH B
Published: January 2024

The Pithoragarh district had 2.23 lakh of cattle and 0.86 lakh buffaloes in 2003. Among the cattle there were 92.81% indigenous and most of them (more than 99%) were non- descript and need their characterization. A survey, including 82 farmers and 194 animals of different age and sex was conducted in 8 villages of Munsyari block of Pithoragarh district to characterize the hill cattle. The survey revealed that large number of hill cattle were available in the remote areas like in Munsyari block of the district and in surrounding areas there were large number of crossbred cattle mainly reared for milk production. In the surveyed area cattle were reared for milk, bullock power and manure. Animals were reared mainly on semi-intensive system of management i.e. grazing from morning to afternoon and thereafter stall feeding. In some villages there were no grazing, all the animals were stall fed. Animals were small in size with cylindrical-shaped body. Body colours vary in different colours i.e. brown, black and white or black & white. Tail was long touching to ground with black or white switch. The ranges of different biometric traits showed that animals were closer to Vechur and Punganaur breeds of cattle for their shape and size but smaller than the Hariana and Sahiwal breeds of cattle. The hill cattle available in Pithoragarh area were smaller in size as compared to hill cattle of Almora and bigger to that of cattle of Rudarprayag district. The average birth weight was 9.14 kg The average age at first calving, daily milk yield, lactation length, dry period, service period and calving interval were 40 months, 1.41 kg, 208 days, 138 days, 105 days and 485 days, respectively. Bullocks of the breed were used for 25–40 days in a year for different agricultural operations. A pair of bullock could plough about 6–8 Nali (0.4 acre) of land in a day.
Red Purnia cattle – an unexplored indigenous germplasm
Authors: CHANDRAN P C , DEY A , PANDIAN S JEGAVEERA , BARARI S K , KAUSHAL D K
Published: January 2024

Purnia cattle are small-to medium-size, distributed in Purnia district and adjoining areas of Araria and Katihar districts of Bihar. Red Purnia are not enlisted among the recognized breeds of cattle in India, as there is lack of preliminary information about the cattle. The cattle exist in two different varieties viz. grey and red. The estimated population of Red Purnia is 2.19 lakhs. The herd size was small with the average of 3.6 and 81% of herds possessed at least 1 cow with 1 or 2 calves. Various morphometric characteristics and body weight of Red Purnia cattle were evaluated on randomly selected 875 animals. Red Purnia cattle are low milk yielders with the average peak yield is 2.88±0.31 litres. These cattle have better reproducing ability with the calving interval of 15.0±0.41 months and 1.31±0.11 number of services/conception. Strategies for genetic improvement of the cattle are discussed.
Effect of concentrate and urea molasses mineral block supplementation on the Effect of concentrate and urea molasses mineral block supplementation on the
Authors: MURALIDHARAN J , SIVAKUMAR K , RAMESH V , PRAKASH SINGH D ANANDHA , SARAVANAKUMAR V RAMESH
Published: January 2024

Present study was carried out to find out the effect of concentrate and urea molasses mineral block supplementation on growth performance of 40 weaned Mecheri ram lambs under two systems of rearing, for 5 months. It was observed that supplementation significantly increased the body weight of grazing lambs and UMMB was found to be a versatile supplement for growing Mecheri sheep. Animals under grazing with supplementation had significantly higher ADG than animals under stall feeding.
Effect of residue incorporation and INM on productivity of spring maize (Zea mays) in rice (Oryza sativa)-based cropping system
Authors: SAHOO PRIYANKA , SINGH THAKAR , SAINI KULVIR SINGH , KAUR JAGMOHAN
Published: January 2024

A field experiment was conducted during 2019 and 2020 at the research farm of Punjab Agricultural University, Ludhiana, Punjab to study the effect of integrated nutrient management (INM) on grain yield, economics, and system productivity of spring maize (Zea mays L.) under residue incorporation in a diversified cropping system. The main plot consisted of 4 treatment combinations, viz. straw removal + 100% NPK + farmyard manure (FYM) @50 t/ha; straw removal + 150% NPK; straw incorporation + 100% NPK + FYM @50 t/ha; and straw incorporation + 150% NPK, while sub-plot consisted of 3 nutrient levels (75%, 100% and 125% NPK) applied to spring maize planted in a single row and double rows on bed. The results revealed that combined application of straw incorporation + 100% NPK + FYM @50 t/ha resulted in significantly higher grain yield (80.1 and 83.6 q/ha), net returns (259.9 and 300.2 ×103 ₹/ha), benefit cost ratio (1.34 and 1.51) and system productivity (82.9 and 89.1 kg/ha/day) of spring maize and application of 125% NPK to double row on bed resulted in significantly higher grain yield (14.6%, 12.9%) and system productivity (5.4%, 4.7%) as compared to 100% NPK to single row on bed during 2019 and 2020, respectively. Residue incorporation along with INM increased grain yield, net returns, nutrient uptake and system productivity of spring maize.
The enunciative mode in the comic "Miss Davis: The life and struggles of Angela Davis"
Authors: Caldas de Souza Dantas Vivianne , Palmira Salme de Aragão Verônica
Published: January 2024

The aim of this paper is to analyze the enunciative mode of discourse, looking at the narrative, descriptive and argumentative modes, both in verbal and non-verbal elements. This work refers to the analysis of the introductory chapter of the book "Miss Davis: THE LIFE AND FIGHTS OF ANGELA DAVIS". The book's introduction is entitled "Black Panther Party Headquarters, Oakland, 1969", in comic strips, which are part of the Black Panther Party's program and present Angela Davis' participation in the party. The research methodology is bibliographical and qualitative, with Patrick Charaudeau's Semiolinguistic Discourse Analysis as its theoretical basis, the Modes of Discourse Organization and, as a basis for analysis, the Enunciative Mode of Discourse. The book is about the progressive struggle of the African-American people for equal rights, with Angela Davis' participation being fundamental for black feminism in the USA. According to Focault (2014), the action of the characters in the comics, when enunciating, questions the sovereignty of truth, which is the concept of hierarchy of the white, cis man. In other words, when the Black Panthers question, they suspend the sovereignty of the discourse of the signifier (the police and the state).
Financial analysis of small hospitals in the state of Pernambuco from 2009 to 2015
Authors: Feitosa Daize Kelly da Silva , Santos Isadora Sabrina Ferreira dos , Souza Kaio Flávio Freitas de , Rodrigues Bárbara Letícia Silvestre , Barreto Isabel de Jesus Brandão , Ribeiro Erlene Roberta
Published: January 2024

This article presents the results of a research that aimed to evaluate the economic and financial performance of the Hospital Units qualified in the National Policy of Small Portiers Hospitals (HPP) in the state of Pernambuco, from 2009 to 2015. In order to discuss the implications of the results for the financial sustainability of the units, indicating possible alternatives. The survey data were obtained from a sample of 59 small hospitals registered in the National Health Establishments Registration System (CNES), through the System Financial Limits of Control Medium and High Complexity (SISMAC) and Information Systems Hospital and ambulatory (SIA and SIH). These secondary data were analyzed by the Consumer Price Index (IPCA). Data analysis showed a significant loss of financial capacity of the studied hospitals and significant differences between the reported amounts of revenues and performance over the years. Showing the need to point out possible strategies redirection of resources or change the service profile of these units and analyze the feasibility of HPP policy.
Sustainability in focus: From management to environmental legislation in Brazil
Authors: Pereira William Marques , Nunes Elen Rosa dos Reis , Santos Giovanna Parisi Cabeça , Rodrigues Zelinda Duarte , Vieira Layane de Souza , Nunes Tiago da Silva , Moreira Auricilene Gomes , Melo Felipe Cristian Neves de
Published: January 2024

The present work aims to analyze the management and its environmental dimension through the premises of sustainability, bringing in this context the importance of legislation relevant to the environment. Thus showing that the legal frameworks referring to the place where life develops in the territory are supported by the Federal Constitution and other various legislations. This research was built from bibliographic studies and documentary analysis in works by the main authors on the relationship management-sustainability-legislation, under a complex view. In this way, a more detailed analysis of the subject is produced, in the search for an understanding of this relationship, showing the importance of environmental licensing in Brazil.
Project #sextoupedagógico for teachers in the municipal school system of Benevides, Pará, Brazil
Authors: Calderaro Kelly Lene Lopes , Silva Francilene Sodré da , Sampaio Antonia Roberta Mitre , Pompeu Josué Lacerda
Published: January 2024

Education is related to activities that provide the student's learning as a way of fully constructing the subject. In this context, the Pedagogy of Projects emerges, a systematic teaching and learning system that is characterized by the systematized conduction of techniques and activities that promote the construction of knowledge. Thus, the present study aimed to analyze the importance of projects in education, emphasizing the role of school management in conducting this methodology. To conduct this work, a bibliographic research was carried out, from which it can be pointed to the fact that Project Pedagogy, despite being a methodology that has been used and disseminated in the educational environment for a long time, still encounters resistance in many school institutions. This fact indicates the need for school management to assume its role in the pedagogical qualification of schools and to equip its teachers to work with projects. This can happen through the organization of times and spaces, the awareness of the school community and the in-service training of teachers, in order to achieve a culture of projects in the school environment.
Entrepreneurial drops: The role of narrative in the simple organic brand
Authors: Coltro Amabile , Oliveira Giulia Loreto Lovo de
Published: January 2024

The aim of this article is to explore the relationship between brand narrative and entrepreneurship, as evidenced in this case study of the Brazilian brand Simple Organic. A thorough literature review reveals that brand narrative is a communication strategy and a tool that can shape the very essence of an enterprise. It can be concluded that, throughout the journey of this natural and organic cosmetics brand, narratives play a crucial role in building the brand's identity, influencing consumer perceptions, and contributing to entrepreneurial success. The choice of Simple Organic as the subject of study is justified by its remarkable rise in the market and its authentic approach, communicating identity, values, and commitments through various channels, from social media to product packaging. This study highlights the importance of this strategic communication in brand perception. Ultimately, this research expands our academic understanding and provides practical guidance for entrepreneurs and marketing professionals seeking to build authentic and impactful brands.
Qualified dating and common-law marriage: A necessary differentiation
Authors: Rodrigues Edwirges Elaine , Alvarenga Maria Amália de Figueiredo Pereira
Published: January 2024

In view of the numerous transformations faced by Family Law, over time, the stable union has been legally recognized as a family entity, and for this purpose, it is enough to fulfill its characterizing elements determined by the legislator. On the other hand, the institute of qualified dating has acquired new contours, becoming the target of jurisprudential and doctrinal discussions, which began to highlight the differences between stable union and the so-called qualified dating, mainly seeking to avoid the possible confusion of legal effects between such institutes. Thus, through the deductive method, a review of the specialized bibliography in Family Law related to the institutes of stable union and qualified dating was carried out, seeking to outline the main element responsible for differentiating them, that is, the animus familiae, in addition to pointing out the effects produced by them and discussing the validity of the dating contract.
Thermorregulation in long distance race: Literature rewiew
Authors: Breguez Igor , Schueda Marco Antonio , Pelchebiski Anna Júlia , Amorim Beatriz Ribeiro da Silva de , Barros Rafaella Gugelmin , Gavronski Thaysa Bruna
Published: January 2024

The literature review of the present study demonstrates that during physical exercise, the body produces heat through the working muscles, generating thermal stress. Through the analysis of articles mainly from the last five years, we concluded that to maintain stable body temperature, the body uses regulatory mechanisms dependent on environmental, task and personal parameters. In intense exercise and in hot environments, blood flow to the skin can increase significantly, and sweating is also increased. However, non-thermal reflexes during exercise cause the regulation of blood flow in the skin to be different from that at rest. The body adjusts the threshold for dilation of skin blood vessels to a higher core body temperature and modifies sensitivity to this temperature change. Regular training improves these adaptations, allowing athletes to dissipate heat more effectively. This review highlights the physiological mechanisms involved in thermal regulation during exercise, discusses the estimation of core temperature in humans, and presents new nutritional approaches to evaluate parameters to maintain stable core temperature.
Uso seguro de produtos químicos do cotidiano - Experiência narrada em uma atividade de extensão
Authors: Santos Theo Álex Souza dos , Fialho Gabriela Silva , Santos José Carlos Oliveira
Published: January 2024

O papel da química em nosso cotidiano é inegável, especialmente quando se trata dos produtos que usamos em nossas casas diariamente. O estudo e compreensão dos produtos químicos e sua aplicação segura no nosso cotidiano desempenham um papel crucial na vida moderna. Este trabalho teve como objetivo promover a conscientização sobre o uso correto de produtos químicos no cotidiano entre os estudantes do Ensino de Jovens e Adultos do Ensino Médio em uma escola da rede pública estadual localizada na Paraíba. A palestra foi concebida como uma iniciativa de compartilhamento de conhecimento com a comunidade escolar externa, como parte das atividades de extensão, uma das áreas de atuação do Programa de Educação Tutorial (PET). A aplicação da palestra foi feita por meio de slides apresentados por parte dos palestrantes e também foi utilizado um questionário desenvolvido e previamente testado para ser aplicado na fase final da palestra. A necessidade de utilizar os produtos químicos domésticos de maneira segura e responsável de grande importância, tanto em nível individual como coletivo. A realização desta atividade extensionista desempenhou um papel crucial para a conscientização das pessoas a respeito do uso correto de domissanitários e os perigos que misturas de produtos químicos podem ocasionar à saúde e ao meio ambiente.
Química, educação e saúde: O impacto dos sais minerais à saúde humana
Authors: Nogueira Jociele Cristine Alves , Gomes Liliane Santos , Santos José Carlos Oliveira
Published: January 2024

Os alimentos possuem nutrientes que se destacam por suas funções químicas específicas e propriedades físico-químicas particulares, e essas determinadas características desempenham papel fundamental no organismo, tendo cada uma suas especificidades, influenciando diretamente suas funções e processos no corpo humano. No âmbito do ensino de Química, um assunto que tem recebido destaque é a química associada aos alimentos, proposta nos documentos oficiais para o ensino. O presente estudo é focado na aplicação de temas contextualizados durante uma aula de química ministrada para estudantes do ensino médio. Esta ação foi desenvolvida no ambiente escolar, especificamente por alunas pertencentes ao grupo PET- Química da Universidade Federal de Campina Grande, cujo objetivo principal é introduzir e destacar o tema “Química e saúde: Benefícios dos Sais Minerais para a nossa saúde" como um assunto relevante no contexto da química e na vida cotidiana dos alunos. De acordo com os resultados, os estudantes afirmaram ter aprendido novos fundamentos acerca dos benefícios dos sais minerais para a saúde por meio da palestra, o que constitui um indicador promissor do impacto educacional subjacente à referida atividade. Adicionalmente, grande parte deles mostrou estar ciente da importância do consumo de alimentos ricos em sais minerais, realçando, assim, a necessidade contínua de disseminação de informações relativas a temática.
Endocardite Infecciosa: Enfoque profilático
Authors: Silva Mayara Angélica Cobuci da , Sousa Guilherme Costa de , Almeida Larah Luzia Costa Corrêa de , Cortela Denise da Costa Boamorte , Sérvio Thaianne Cavalcante , Gattas Leila Valderes Souza
Published: January 2024

A Endocardite Infecciosa (EI) é uma complicação de elevada morbimortalidade e potencialmente evitável em pacientes valvopatas. Praticamente qualquer agente pode causar EI, embora os mais frequentes sejam bactérias gram-positivas, principalmente Staphylococcus, Streptococcus e Enterococcus.
Phishing in Web 3.0
Authors: Elatoubi Mohamed
Published: January 2024

The emergence of Web 3.0 technologies is undoubtedly shifting the phishing threat landscape by empowering traditional attack vectors and forcing attackers to adapt and leverage new techniques. Offering new opportunities for the attackers to exploit and adding new challenges for cybersecurity professionals. This paper aims to exhibit the evolution of phishing attacks in Web 3.0, the different techniques and novel technologies cybercriminals leverage for scaling phishing campaigns, and explores the challenges and promising solutions defenders can adopt to narrow the strategic gap in this emerging component of the attack vector. The paper commences by summarizing the different wide web generations until it reaches Web 3.0 and starts exploring its architectural distinguishing features. Afterward, it deductively treats the convoluting threats of the new web technology as an entrance to focus on phishing attacks by discussing the concept of phishing from various angles while shedding light on emerging threats from phishing 3.0 and potential solutions that can make a substantial impact.
Quantitative Models for Supply Chain Risk Analysis in Water Tank Manufacturing: A Case Study of a Factory in Aba, Nigeria
Authors: Ezeaku N. I. , Uzorh A. C. , Obiukwu O. O. , Godwin S. I. , Ekpechi D. A.
Published: January 2024

Quantitative models for supply chain risk analysis of water tank manufacturing company factory Aba, Abia state has been studied. Aba being one of the biggest cities known for commercial activities in southern part of Nigeria, couple the weight of weight and area of a water tank, has made the supply mechanism of the product costly.  This study delves into the complexities of supply chain management, aiming to identify risk assessment models, vulnerabilities, propose optimal scenarios, and recommend enhanced risk management strategies. Risk factors identification, route time estimation, critical path analysis, cost-related risk assessment, comparison of logistic choices, and decision tree and mitigation were used to instigate and determine the best path for the supply flow of the system and save cost.  From the results obtained, the analysis reveals that PATH 6 is the most time-efficient route, with the critical path identified as 62 hours, furthermore, two transportation/logistic choices were compared, with the second choice considered more cost-effective (N6.6m) than the first (N6.9m), the developed decision tree model, explores vulnerabilities in the supply chain and proposes mitigation strategies. This research has suggested some applicable guides to optimize supply chain managements, which includes partnering with distributors, leasing warehouses, or collaborating with retailers, with each decision weighed against various factors and costs to align with the company's best interests. The study underscores the importance of considering every component of the supply chain during decision-making to effectively mitigate risks.
The Effect of Supplementing White Sweet Lupine Grain Meal (Lupinus albus L.) on Blood and Milk Metabolites, Milk Yield, and Quality of Dairy Cows in Ethiopia
Authors: Birhan Malede , Mekuriaw Yeshambel , Tassew Asaminew , Tegegne Firew
Published: January 2024

Feed is the cornerstone of dairy production, serving as a crucial input for sustainable milk production. This trial aimed to investigate the effect of white sweet lupine grain meal inclusion on feed intake, blood and milk metabolites, milk yield, and quality. The experimental cows had a parity of 2±0.71 (mean ± SD), a daily milk yield of 12.72 ± 0.9, and an average body weight of 412.6 ± 21.5 kg. The varying proportions of treatment diets were: 75, 50, 25 and 0% (T1, T2, T3 and T4) treatment groups respectively. Data collected during the study were subjected to analysis of variance to determine significant differences. Cows fed diet T1 showed a better dry matter (10.39 kg/day), organic matter (7.31 kg/day), nitrogen (2.42 kg/day), and NDF intakes (3.75 kg/day) that had significant difference on (p<0.05). When lupine inclusions dropped from 75 to 50 and even to 25%, the N digestibility decreased from 76.63, 70.66, and 65.6%, respectively, and the digestibility of N in all treatment diets significantly decreased (p < 0.01). Once more, cows fed T1 diet had the highest (p<0.01) plasma glucose concentration (116.81 mg/dl) among the four experimental groups. Cows fed T2 and T4 diets showed significant variation at (p<0.05) in plasma glucose levels, with values of 108.7 and 110.16 mg/dl, respectively. Cows fed T1 had relatively lower plasma beta-Hydroxybutyric acid and non-esterified fatty acid concentrations (p<0.05) than others, with mean values of 3.23 and 1.28 mg/dl respectively. The partial inclusion of white sweet lupine grain meal up to the level of 75% is highly suggested as a better alternative feed source.
Antibacterial Activity of Some Selected Marine Macro-algae from Rameswaram Coastal Region, India
Authors: Selvaraj Nandhini , Francis Mishel , Senthilkumar Pavithra , Annamalai Aravinth , Sivakumar Saroja Ramasubbu
Published: January 2024

Marine algae are known as source of bioactive secondary metabolites. Twenty macroalgae were collected from Mandapam cost, Gulf of Mannar, Rameswaram were tested against two-gram negative bacteria’s using agar well diffusion method. The following species were used in the current study include seven species in Chlorophyta (Caulerpa peltata, Ulva lactuca, Halimeda gracilis , Chaetomorpha aerea, Cladophora vagabunda, Enteromorpha flexuosa, Halimida macroloba), seven in Phaeophyta (Sargassum cinereum, Padina boergesenii, Sargassum cristaefolium, Turbinaria decurrens,  Turbinaria conoides, Hydroclathrus clathratus, Lobophora variegate) and six in Rhodophyta (Hypnea spicefera, Solieria robusta, Porphyra indica, Ceramium rubrum, Gelidiella acerosa  Gracilaria edulis). They were air-dried thoroughly and powdered using a grinder. Powdered algae were extracted using solvents such as water, ethanol and methanol. In the present study ethanol extract was found to be excellent antibacterial activity from macroalgae. Among the selected Twenty different macroalgae the red algae (Rhodophyta) showed the higher antibacterial activity followed by brown (Phaeophyta) and green (Chlorophyta) against the tested two selective negative bacteria (Pseudomonas aeruginosa and Klebsiella pneumoniae).  This finding supports the view that algal extracts are a reliable source of bioactive compounds for upcoming medication development.
Implementation and Fabrication of Hybrid Solar Inverter
Authors: Nasir Areeba , Gull Nayab , Ahmad Raees , Raza Syed Saqlain
Published: January 2024

Inverters are frequently utilized in home and industrial settings to act as an alternative source of electricity in case the utility network's electrical supply is interrupted. However, due to the low capacity of the battery, the inverter was shut down for the heavy-load appliances. This endeavour is constructed in a way that uses solar energy to get around this restriction. An inverter powered by a battery makes up the hybrid inverter with a solar battery charging system. It incorporates maximum power point tracking (MPPT) to extract maximum power from the solar panels and efficiently charge the batteries. With the assistance of driver circuitry and a transformer, this inverter can generate up to 230V. The solar power source itself and the grid power supply are used to charge the battery. If the solar power supply is available, the relay circuitry uses the solar power to supply the load. Otherwise, the load connects to the grid power supply. The battery is also charged by this solar power source to be used as a backup in the future. When solar power is unavailable, charging the battery with the main supply is a pleasant option. As a result, this inverter may last longer and give the consumer an uninterrupted power supply.
Histopathological results after MRТ/US fusion guided biopsy of prostate lesions classified asPIRADS 3
Authors:   Clinic of Urology, Military Medical Academy, Sofia, Bulgaria, Todorova Viktoria , Gatsev Ognyan ,   Clinic of Urology, Military Medical Academy, Sofia, Bulgaria, Petrov Petar ,   Clinic of Urology, Military Medical Academy, Sofia, Bulgaria, Hristov Konstatin , Petkova Kremena ,   Clinic of Urology, Military Medical Academy, Sofia, Bulgaria,   Clinic of Urology, Military Medical Academy, Sofia, Bulgaria, Saltirov Iliya ,   Clinic of Urology, Military Medical Academy, Sofia, Bulgaria
Published: January 2024

Introduction: Мagnetic resonance tomography (MRT) has become an established part of prostate cancer diagnosis. MRT/US fusion guided biopsy enables obtaining tissue samples directly from lesions suspected for prostate cancer. The introduction of the Prostate Imaging-Reporting and Data System (PI-RADS) precises the cases in which performance of target biopsy is needed by categorization of suspected prostate lesions according to the probability of detecting prostate cancer. It is debatable whether PI-RADS 3 lesions in MRТ (MRТ) represent a significant risk for prostate cancer. Objectivе: The objective of this study is to assess the incidence of carcinoma-positive histological results in PIRADS 3 compliant lesions from MRТ. Material and methods: Medical records of 99 patients, who underwent transperineal MRТ/US fusion prostate biopsy of suspicious lesions on MRТ, classified as PI-RADS 3, between January 2019 and December 2022 were retrospectively analyzed. Results: Patients` mean age was 65.6±6.8 years. Mean volume of the prostate gland was 54.2±20.2 cc and the mean value of prostate-specific antigen was 18.5±6.3. Pathologic finding from digital rectal examination of the prostate gland appeared in 18 (18.2%) patients. Mean size of the lesion from MRI was 12.9±5.24 mm. The suspect lesions were localized mainly in the peripheral zone of the prostate gland – 60 (60.6%), secondly in the transitional zone – 35 (35.4%). Seminal vesicles invasion and lymphade-nomegaly were rare – 1 (1%) and 2 (2%) cases. Histopathological results in 63 (63.6%) patients was benign prostatic hyperplasia. 24 (24.2%) lesions were classified as 3+3=6 according to Gleason Score, 4 (4.0%) as 3+4=7 and 8 (8.1%) as 4+3=7. Conclusion: The results of this retrospective study shows that PI-RADS 3 lesions take an intermediate position in regard to histopathological findings. The resulting almost equal number of patients diagnosed with BPH and prostate cancer is proof of this. PI-RADS 3 lesions carry a relatively small risk of clinically significant cancer (csPCa).
Future Perspectives: A Literature Review of the Urologist’s New Potential Tool-Artificial Intelligence
Authors:   Clinic of Urology, UMBAL SofiaMed, Sofia, Krastev Kristiyan , Tsvetkov Nikola ,   Clinic of Urology, UMBAL SofiaMed, Sofia, Stoyanov Nikola ,   Clinic of Urology, UMBAL SofiaMed, Sofia, Ibrahimov Korai ,   Clinic of Urology, UMBAL SofiaMed, Sofia, Davidov Kaloyan ,   Clinic of Urology, UMBAL SofiaMed, Sofia
Published: January 2024

Introduction: The overview aims to present the current state of artificial intelligence (AI) tools in the decision-making process, diagnosis, treatment possibilities, or outcome predictions in functional urology. Terminology: Artificial intelligence in healthcare includes computer systems that use reasoning and learning to analyze complex medical data and make predictions. Machine learning focuses on training computers with data to improve performance over time, especially in the case of processing medical information. Deep learning uses complex neural networks, inspired by the functional structure of the human brain, to extract information from medical data, improving the accuracy of diagnoses and speeding up investigations. Current AI Applications in Urology: The integration of artificial intelligence (AI) and artificial neural networks (ANN) in urological practice as a branch of medicine represents a promising potential for improving various aspects of patient care, diagnosis, surgical approaches with subsequent procedures resulting from rational and quick decision-making in the management of urological diseases (urolithiasis, BPH, oncology). AI technologies provide the opportunity to analyze large volumes of complex data, assist in clinical decision-making, optimize treatment strategies, and improve patient outcomes. Conclusion: The future and potential prospects of artificial intelligence as an auxiliary tool are significant, and the complete transition to them is still ahead. The field of AI support in urology is rapidly evolving, with continuous research and development focused on increasing the accuracy of diagnostic tools, refining surgical techniques, and improving treatment optimization. Continued research and clinical trials will be crucial for validating the effectiveness of AI and directing their integration into everyday urological practice.
Klasterisasi Kabupaten/Kota di Provinsi Kalimantan Barat Berdasarkan Rasio Guru dengan Murid di Tingkat SD, SMA, dan SMA Serta IPM Tahun 2022 Menggunakan Metode K-Means Clustering
Authors: Tri Putra Mufrih Nur Huda
Published: January 2024

Pemerintah Provinsi Kalimantan Barat ingin mengadakan percepatan peningkatan IPM sehingga dengan adanya penelitian ini dapat mengkategorikan kabupaten dan kota yang sebaiknya diberikan perhatian lebih dalam pembangunan pendidikan di wilayah tersebut. Tujuan dari penulisan jurnal ini adalh untuk mengkategorikan kabupaten dan kota yang ada di Provinsi Kalimantan Barat berdasarkan rasio guru dengan murid di tingkat SD, SMP, dan SMU serta IPM tahun 2022 sehingga dapat menjadi pertimbangan mengambil kebijakan dalam percepatan peningkatan IPM dari dimensi pengetahuan. Data yang digunakan dalam penelitian ini adalah data yang diunduh dari laman BPS Provinsi Kalimantan Barat. Data dianalisis menggunakan metode analisis klaster dengan metode pengklasteran K-means untuk membentuk beberapa klaster. Hasil yang diperoleh terbentuk tiga klaster, yaitu klaster 0, 1, dan 2. Klaster 0 dengan karakteristik rasio SD tinggi, rasio SMP tinggi, rasio SMU sedang, dan IPM tinggi. Klaster 1 dengan karakteristik rasio SD rendah, rasio SMP rendah, rasio SMU rendah, dan IPM rendah. Klaster 2 dengan karakteristik rasio SD sedang, rasio SMP sedang, rasio SMU tinggi, dan IPM sedang.
Movement Disorders Induced by Neurotoxins
Authors: Almikhlafi Mohannad A.
Published: January 2024

Parkinson’s disease (PD), first described by James Parkinson, remains the most prevalent neurological movement disorder in aging populations. This debilitating condition is characterized by the progressive degeneration of dopaminergic neurons within the substantia nigra (SN) pars compacta. Despite its discovery over two centuries ago, the etiology of PD remains elusive. To gain deeper insights into the underlying pathology, disease progression mechanisms, and potential therapeutic targets for symptom amelioration, animal models have emerged as invaluable tools. Among these, neurotoxins such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 6-hydroxydopamine (6-OHDA) are extensively utilized to induce acute PD models in mice and rats, respectively. This review comprehensively explores the contributions of these neurotoxin-induced models toward enhancing our understanding of PD pathogenesis and advancing therapeutic interventions. Additionally, it highlights key findings and promising avenues for future research in this critical area of movement disorders.
Synthesis and Photocatalytic Applications of Silver Sulfide Nanostructures: Recent Advancement
Authors: Kumar Umesh , Shekhar Aparna , Arora Vaishali , Singh Parul
Published: January 2024

Silver sulfide nanoparticles belong to the family of important metal chalcogenides. Silver sulfide has been extensively studied in recent years due to its applications in various fields ranging from biosensors, infrared detectors, and optoelectronics to catalysis. Silver sulfide is considered as a potential photocatalyst due to narrow band gap energy, mechanical and thermal stability, cyclability, and ease of synthesis. Different methods have been investigated to produce various forms of silver sulfide nanoparticles. The present chapter focuses on the recent progress in synthesis of silver sulfide nanoparticles using hydrothermal method, chemical bath deposition, microwave-based approach, sonochemical method, single molecular precursor’s decomposition, and green synthesis. Moreover, the application of silver sulfide nanoparticles in photocatalytic degradation of organic dyes is discussed in details.
Pulmonary Hypertension with “Normal” Pulmonary Vascular Resistance
Authors: Jumean Marwan , Nathan Sriram , Aponte Maria
Published: January 2024

Abstracts not available for Perspectives.
Hemodynamic Variations in Cardiogenic Shock Phenotypes
Authors: Katz Jason
Published: January 2024

Patients with cardiogenic shock are not all the same. They present with a variety of hemodynamic profiles and other features that may allow us to create specific phenotypes. It is possible that phenotyping these patients at presentation may then help us to identify the optimal and earliest therapies that will improve outcomes and, at the same time, help us to overcome some of the heterogeneity currently undermining clinical trials.
Houston SHOCK: A Practical Scoring System Incorporating Cardiogenic Shock Dynamic Changes
Authors: Jumean Marwan , Nathan Sriram , Gregoric Igor , Kar Biswajit
Published: January 2024

Cardiogenic shock has an unacceptably high mortality rate and additional tools are needed to improve outcomes. The Society of Cardiovascular Angiography and Interventions (SCAI) shock severity classification has provided a unified definition of shock severity that has proven to be reproducible and predictive of survival. However, cardiogenic shock assessment goes beyond standardizing its severity, and a uniform and practical approach to comprehensive assessment that may guide therapy in a dynamic state is currently lacking. Since cardiogenic shock is a rapidly evolving pathophysiological catastrophe, we propose a new assessment tool – the Houston SHOCK Score – which incorporates dynamic changes. The acronym SHOCK can be used to emphasize five key aspects of patients in cardiogenic shock: Severity, Hemodynamics, Onset, Causes, and Kinetics. We believe this tool provides physicians with vital information that will facilitate appropriate care by incorporating dynamic changes in the patient’s profile.
Surviving Sepsis Campaign: Strategies to Implement in Cardiogenic Shock Management
Authors: Burke James
Published: January 2024

The Surviving Sepsis Guidelines can serve as a structure to help educate and create a set of recommendations on how to care for patients through this complicated pathway of shock. Designing a cardiogenic shock bundle could reduce the variability of care and possibly improve survival. Also, a more standard protocol would allow a review of the outcomes and a system to change practice nationally when new data or technology becomes available. This could create a continuous quality improvement cycle. Creating a “Surviving Cardiogenic Shock” system could help provide awareness for recognition of cardiogenic shock and advanced management alternatives needed at level one and two hospitals. The creation of cardiogenic shock systems of care would support smaller hospitals with a Hub and Spoke structure. Cardiogenic shock is not septic shock, but those in cardiology and cardiac critical care can and should take lessons from the Surviving Sepsis Campaign.
Future Perspectiv erspectives in Acute My es in Acute Myocarditis Complicated by Cardiogenic Shock
Authors: Tavecchia Giovanni , Cartella Iside , Ammirati Enrico
Published: January 2024

Acute myocarditis is an inflammatory disease of the myocardium with a highly variable clinical course. Fulminant myocarditis (FM) represents the most threatening scenario with hemodynamic compromise and cardiogenic shock at presentation. Despite medical advances and the availability of promising mechanical circulatory support (MCS), FM is burdened by a dismal prognosis. Early referral to tertiary hospitals with MCS facilities and prompt diagnosis with endomyocardial biopsy are critical steps toward optimal management. Moreover, beyond supportive care, the prevention of irreversible myocardial damage with immunomodulating therapies must be proven in clinical trials. In this editorial, we briefly describe current evidence and future perspectives regarding the management of myocarditis complicated by cardiogenic shock.
Racial Variations in Shock Presentation and Outcome
Authors: Bailey Steven
Published: January 2024

Working toward inclusive strategies for data sampling, trials, and triage is essential. Whatever the approach, it is important to do better than what has been done in the past when considering race and ethnicity in patient care. Although there may be limited publications with information on this topic, they have shown clear differences in patient outcomes with possible associations with gender, race, and ethnicity. It is critical to view the implications of this on socioeconomic status, access, resources, patient phenotypes, and patient desires and expectations. The disparities must first be recognized before any treatment options can be identified.
Hyperthermic Extr thermic Extracorpor acorporeal Applied T eal Applied Tumor Ther umor Therapy (HEATT®) in Advanced Unresponsive Cancer
Authors: Zwischenberger Joseph , Skaggs Peyton , Breetz Katherine , Winetz Jan , Vertrees Roger
Published: January 2024

Hyperthermia has been utilized for cancer therapy, including metastatic cancer, for decades with isolated success. Previous research has indicated that the elevated temperature of 42°C induces cell death, apoptosis, or senescence of responsive cancers, providing a mechanism for tumor destruction and management. Veno-venous perfusion-induced systemic hyperthermia (V-V PISH) may be the key to improving advanced tumor responsiveness to previously failed chemotherapy and/or radiation as combination therapy. The most recent iteration of V-V PISH, Hyperthermic Extracorporeal Applied Tumor Therapy (HEATT®), provides homogeneous heating of all tissues with electrolyte and pH control and continues to prove safe and effective. The utilization of HEATT® in advanced, unresponsive cancers should be further explored as a part of integrative oncology care.
Exégesis agustiniana en los libros XV, XVI y XVII del De Ciuitate Dei
Authors: Sánchez-Andrés María ,   Order of Augustinian Recollects
Published: January 2024

En el artículo se aborda la exégesis bíblica agustiniana presente en los libros XV a XVII del De ciuitate Dei. Con relación al libro XV se analiza la autoridad que el Hiponense les confiere a las Escrituras. Posteriormente se destaca el tema de la inspiración de la Sagrada Escritura, como obra del Espíritu Santo. En vista de que en el libro XV del De ciuitate Dei san Agustín da una gran importancia a las diferentes versiones bíblicas, el artículo hace una breve presentación de las versiones bíblicas mencionadas por san Agustín, para exponer la autoridad y validez que les confería a las mismas. Se expone la interpretación exegética de los nombres de los personajes del Antiguo Testamento. Se hace asimismo referencia a las consideraciones intratextuales que san Agustín hace dentro del libro XV, particularmente las relativas al Contra Faustum y sus implicaciones exegéticas. Con relación a los libros XVI y XVII se hace la presentación de los principales elementos exegéticos que el obispo de Hipona desarrolla dentro de los libros XVI y XVII del De ciuitate Dei- Se destacan, en primer lugar, los principios generales exegéticos que san Agustín ofrece en los dos libros anteriormente mencionados. Posteriormente el artículo presenta el vocabulario utilizado por el Obispo de Hipona para designar la labor exegética hecha por él, así como las diversas implicaciones y aplicaciones de la hermenéutica bíblica. En tercer lugar se ponen de manifiesto las diversas interpretaciones e implicaciones espirituales que tienen para san Agustín los nombres de personajes y lugares del Antiguo Testamento mencionados en estos dos libros.