bluuebunny/crossref_metadata_2025 huggingface dataset:
Survivors’ perceptions regarding the follow-up of pain complaints after breast cancer treatment: Distinct coping patterns
Authors: Slaghmuylder Yaël , Lauwerier Emelien , Pype Peter
Published: January 2023

Introduction

After finishing cancer treatment, breast cancer survivors often experience both physical and psychosocial symptoms such as pain. In some, pain can persist for months or even years. Pain is a complex experience. Its occurrence and maintenance are explained through interactions between multiple factors, which are biological/physiological, psychological, and social in nature. Unaddressed needs related to this problem - such as insufficient pain relief, limited validation of the problem, and minimal physical and psychological support - may cause severe disability and negatively impact well-being and quality of life. This study investigated how breast cancer survivors perceive their (chronic) pain complaints to be addressed during follow-up care. Furthermore, we explored how they coped with the way their trajectories happened to unfold.

Methods

We conducted four focus groups with a total of thirty-one breast cancer survivors. Each focus group consisted of an asynchronous part with an online discussion platform and a synchronous part through video calls. Data analysis was guided by the Qualitative Analysis Guide of Leuven.

Results

Narratives revealed the unmet needs of survivors and showed variability in the lived experiences of having to deal with pain. Some survivors tend to ignore the pain, while others look for solutions to reduce pain. A third coping pattern is accepting pain and its impact. Furthermore, how survivors cope with pain is influenced by intrapersonal, interpersonal, and societal processes. For example, pain-related beliefs and prejudices among healthcare providers, family, friends, colleagues, other cancer survivors, and society could possibly steer a survivor towards a certain way of coping. In these processes, the role of healthcare providers seems pivotal. For instance, when survivors do not feel heard or taken seriously by healthcare providers, their acceptance of pain can be impeded.

Discussion

To conclude, a person’s way of coping with pain and the associated needs is dynamic and influenced by factors at multiple levels such as the intrapersonal, interpersonal and societal level. To sufficiently address the problem of pain among cancer survivors, we therefore also need actions that tackle the health care system and its stakeholders, as well as the public debate concerning cancer follow-up care.
Intention to consume news via personal social media network and political trust among young people: The evidence from Hong Kong
Authors: Zhang Youliang , Tian Zhen , Zhou Ziwei , Huang Jing , Zhu Alex Yue Feng
Published: January 2023

Introduction

Assessing the effect of different media sources on political trust provides an overall picture of the role of the current media landscape in influencing the legitimacy of political institutions.

Methods

A cross-lagged model was developed and tested by applying it to a three-wave dataset obtained by surveying young people in Hong Kong in order to evaluate the unique impact of intention to consume newsviapersonal social media network on political trust.

Results

After controlling for the impact of other news channels and respondents’ prior political interest, we found their political trust was most significantly affected by information intentionally obtained from friends and family through their personal social media network.

Discussion

Media exhibits a relatively weak effect on political trust, which is primarily influenced by selection, indicating that policymakers do not have to be concerned with online exchange of information that is critical of the government. Moreover, this evidence from Hong Kong suggests that, when it comes to developing political trust throughout the society, conflicts resulting from opposing views are better than ignorance.
Living in ancestrally diverse states of the United States is associated with greater vagal tone
Authors: Harrod Ethan G. , Shrira Ilan , Martin Jared D. , Niedenthal Paula M.
Published: January 2023

Historically, exposure to dissimilar others (“strangers”) was a physiologically arousing event—resulting in avoidance, distrust, and even conflict. Despite this, contemporary migration patterns are increasing intergroup contact. What gives rise to an individual’s ability to regulate their arousal such that social engagement with outgroup members is possible? We propose that cultural practices that evolve in ancestrally diverse, compared to ancestrally homogeneous, societies provide more opportunities for society members to engage in emotion regulation. This regulatory exercise, in turn, promotes higher vagal tone—a physiological indicator of one’s ability to effectively manage arousal in social interaction. In a secondary analysis of data from the MIDUS 2 Biomarker Project, we find that the ancestral diversity of the states of the United States significantly predicts the average vagal tone of the state’s citizens. The findings suggest that social context is associated with predictable and significant adaptations of human physiology over individual lifetimes.
Research on paths of opportunistic behavior avoidance and performance improvement in food supply chain from the perspective of social control
Authors: Lyu Tu , Guo Yulin , Geng Qixiang
Published: January 2023

It is essential to avoid opportunistic behaviors of food supply chain members to guarantee food safety and sustainable supply. This research adopted the perspective of supply chain membership governance to discuss the critical mechanisms of opportunistic behavior avoidance and performance improvement in the food supply chain. Two information-sharing mechanisms (information sharing with customers and information sharing with suppliers) were used as mediating variables to explore the mechanisms of how social control, information sharing, and opportunistic behavior worked on supply chain performance. Furthermore, an online questionnaire survey was conducted to collect 210 data samples from the food manufacturing industry in China, and the structural equation model method was applied to test the research hypotheses. According to the empirical research findings, social control can directly reduce opportunistic behaviors of supply chain members and reduce such behaviors indirectly via the mediating factor of information sharing; social control affects the supply chain performance via the mediating factors of information sharing and opportunistic behavior, instead of directly improving supply chain performance. Two information sharing mechanisms vary in their mechanism of influence. Information sharing with customers reduces opportunistic behaviors, but does not directly improve supply chain performance. Information sharing with suppliers enhances supply chain performance and reduces opportunistic behaviors. This research offers theoretical and practical suggestions for performance improvement and opportunistic behavior avoidance to promote food supply chain management.
Mindfulness and compassion training for health professionals: A qualitative study
Authors: Brun Clémence , Akinyemi Alexis , Houtin Laurène , Mizzi Claire , Cardoso Thierry , Isnard Bagnis Corinne
Published: January 2023

Background

Compassion is a key component of quality care. Encouraging Health Care Professionals (HCPs) to develop a patient-centered care relationship through mindfulness and compassion training may be beneficial for both patients and HCPs.

Method

We assessed the impact of a compassion-centered mindfulness program [i.e., the Mindfulness Based (MB) CARE program] on healthcare practice conducting 10 phone interviews with HCPs who experienced the program.

Results

The training had an overall positive impact on the HCPs ability to feel compassion toward their patients and themselves, helped them develop kindness toward themselves and their patients, and enhanced their attention to their patient’s needs and theirs. Participants were better able to accept the difficult work experiences or those their patients experienced, with more perceived equanimity and less reactivity.

Conclusion

Professional mindfulness and compassion training programs could be operational levers for institutions aiming at fostering more compassionate HCPs–patients relationships.
I will speak up if I feel energetic: Effects of supervisor humor on employee voice
Authors: Li Daiheng , Liu Pan , Li Shuang , He Jieya
Published: January 2023

Extant literature on supervisor humor predominantly documents its beneficial effects on the organization, but its dark side receives little attention. Drawing on ego depletion theory, we proposed a conceptual model to examine the effects of two interpersonal types of supervisor humor (i.e., affiliative humor and aggressive humor) on employee voice. An empirical study with a sample covering 257 employees in China indicated that supervisor aggressive humor was negatively related to voice behaviorsviadepleting employees’ resource. In contrast, supervisor affiliative humor was positively related to voice behaviors owing to less depletion of employees. Contrary to prediction, emotional intelligence enhanced the positive effect of supervisor aggressive humor on employees’ depletion. Important theoretical and practical implications were discussed.
Performance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia
Authors: Gaubert Malo , Dell’Orco Andrea , Lange Catharina , Garnier-Crussard Antoine , Zimmermann Isabella , Dyrba Martin , Duering Marco , Ziegler Gabriel , Peters Oliver , Preis Lukas , Priller Josef , Spruth Eike Jakob , Schneider Anja , Fliessbach Klaus , Wiltfang Jens , Schott Björn H. , Maier Franziska , Glanz Wenzel , Buerger Katharina , Janowitz Daniel , Perneczky Robert , Rauchmann Boris-Stephan , Teipel Stefan , Kilimann Ingo , Laske Christoph , Munk Matthias H. , Spottke Annika , Roy Nina , Dobisch Laura , Ewers Michael , Dechent Peter , Haynes John Dylan , Scheffler Klaus , Düzel Emrah , Jessen Frank , Wirth Miranka ,   for the DELCODE study group
Published: January 2023

Background

White matter hyperintensities (WMH), a biomarker of small vessel disease, are often found in Alzheimer’s disease (AD) and their advanced detection and quantification can be beneficial for research and clinical applications. To investigate WMH in large-scale multicenter studies on cognitive impairment and AD, appropriate automated WMH segmentation algorithms are required. This study aimed to compare the performance of segmentation tools and provide information on their application in multicenter research.

Methods

We used a pseudo-randomly selected dataset (n = 50) from the DZNE-multicenter observational Longitudinal Cognitive Impairment and Dementia Study (DELCODE) that included 3D fluid-attenuated inversion recovery (FLAIR) images from participants across the cognitive continuum. Performances of top-rated algorithms for automated WMH segmentation [Brain Intensity Abnormality Classification Algorithm (BIANCA), lesion segmentation toolbox (LST), lesion growth algorithm (LGA), LST lesion prediction algorithm (LPA), pgs, and sysu_media] were compared to manual reference segmentation (RS).

Results

Across tools, segmentation performance was moderate for global WMH volume and number of detected lesions. After retraining on a DELCODE subset, the deep learning algorithm sysu_media showed the highest performances with an average Dice’s coefficient of 0.702 (±0.109 SD) for volume and a mean F1-score of 0.642 (±0.109 SD) for the number of lesions. The intra-class correlation was excellent for all algorithms (>0.9) but BIANCA (0.835). Performance improved with high WMH burden and varied across brain regions.

Conclusion

To conclude, the deep learning algorithm, when retrained, performed well in the multicenter context. Nevertheless, the performance was close to traditional methods. We provide methodological recommendations for future studies using automated WMH segmentation to quantify and assess WMH along the continuum of cognitive impairment and AD dementia.
Medical outcomes study social support survey (MOS-SSS) in patients with chronic disease: A psychometric assessment
Authors: Merino-Soto Cesar , Núñez Benítez Miguel Ángel , Domínguez-Guedea Miriam Teresa , Toledano-Toledano Filiberto , Moral de la Rubia José , Astudillo-García Claudia I. , Rivera-Rivera Leonor , Leyva-López Ahidée , Angulo-Ramos Marisol , Flores Laguna Omar Arodi , Hernández-Salinas Gregorio , Rodríguez Castro Jorge Homero , González Peña Omar Israel , Garduño Espinosa Juan
Published: January 2023

Purpose

Currently, information on the psychometric properties of the Medical outcomes study-social support survey (MOS-SSS) for patients with chronic disease in primary health care, suggests problems in the dimensionality, specifically predominant unidimensionality in a multidimensional measure. The aim of this study was to determine the internal structure (dimensionality, measurement invariance and reliability) and association with other variables.

Methods

A total of 470 patients with chronic disease from a Family Medicine Unit at the Instituto Mexicano del Seguro Social, IMSS, with a mean age of 51.51 years were included. Participants responded to the Questionnaire of Sociodemographic Variables (Q-SV), SF-36 Health-Related Quality of Life Scale–version 1.1, and MOS-SSS.

Results

Non-parametric (Mokken scaling analysis) and parametric (confirmatory factor analysis) analyses indicated unidimensionality, and three-factor model was not representative. A new 8-item version (MOS-S) was developed, where measurement invariance, equivalence with the long version, reliability, and relationship with the SF-36 were satisfactory.

Conclusion

The MOS-SSS scale is unidimensional, and the shortened version yields valid and reliable scores for measuring social support in patients with chronic disease at the primary health care.
Loneliness in sports active and non-active school-age children: Can sport protect children against loneliness?
Authors: Tubić Tatjana , Modrić Toni , Sekulić Damir , Bianco Antonino , Radjo Izet , Drid Patrik
Published: January 2023

Introduction

This study aims to examine can sport protect children against loneliness and, if yes, whether this relationship depends on gender and/or sports-related variables.

Methods

The sample includes 762 10-year-old children (414 boys). The total score of The Children's Loneliness Scale is a dependent variable in the study, while sports participation (sports active—individual or team sports, or non-active) and level/duration of sports participation are independent variables.

Results

Obtained results indicate that the degree of loneliness differs depending on gender and whether the children are in sports activities or not. Unlike the level of sports participation, the duration of sports participation is relevant to the loneliness degree in both boys and girls.

Discussion

This research results could represent the right direction for educators and/or parents in their endeavor to preserve and develop school-age children's mental health.
Inflammation mediated the effect of dietary fiber on depressive symptoms
Authors: Zhang Ting , Cui Xiao-mei , Zhang Yu-ying , Xie Tao , Deng Yuan-jia , Guo Fang-xi , Wang Qi , Wu Qing-feng , Dong Ming-hua , Luo Xiao-ting
Published: January 2023

Background and aims

Previous studies showed that inflammation affects depressive symptoms. Dietary fiber may be associated with inflammation and depressive symptoms. We aimed to investigate the relationship between inflammation and depressive symptoms at different levels of dietary fiber intake and to explore whether dietary fiber affects depression through inflammation.

Methods

A total of 8,430 National Health and Nutrition Examination Survey (NHANES) samples were collected between 2015 and 2018. Factor analysis was used to determine dietary patterns. Linear regression and logistic regression analysis were used to explore the relationship between nutrients, inflammation, and depressive symptoms, and the mediation analysis was conducted using the bootstrap method.

Results

Factor 3 (dietary fiber and vitamins) was inversely associated with depressive symptoms and inflammation. The upper quartile scores of the dietary inflammatory index (DII) and C-reactive protein (CRP) were associated with depressive symptoms compared with controls (DII: OR = 1.851, 95% CI: 1.267–2.705; CRP: OR = 1.737, 95% CI: 1.136–2.656). The DII score and CRP were associated with depressive symptoms in the group with low dietary fiber intake (DII: OR = 2.736, 95% CI: 1.628–4.598; CRP: OR = 2.092, 95% CI: 1.196–3.658) but not in the high dietary fiber intake group. Mediating analysis showed that CRP partially mediated the effect of dietary fiber intake on depressive symptoms (βindirect = −0.0025, 95% CI: −0.0038 to −0.0013), and the mediated proportion was 10.5%.

Conclusion

In this study, we found that DII scores and CRP were not associated with depressive symptoms in participants with high dietary fiber intake, and inflammation partially mediates the effect of dietary fiber on depressive symptoms.
Identifying risk factors of developing type 2 diabetes from an adult population with initial prediabetes using a Bayesian network
Authors: Fuster-Parra Pilar , Yañez Aina M. , López-González Arturo , Aguiló A. , Bennasar-Veny Miquel
Published: January 2023

Background

It is known that people with prediabetes increase their risk of developing type 2 diabetes (T2D), which constitutes a global public health concern, and it is associated with other diseases such as cardiovascular disease.

Methods

This study aimed to determine those factors with high influence in the development of T2D once prediabetes has been diagnosed, through a Bayesian network (BN), which can help to prevent T2D. Furthermore, the set of features with the strongest influences on T2D can be determined through the Markov blanket. A BN model for T2D was built from a dataset composed of 12 relevant features of the T2D domain, determining the dependencies and conditional independencies from empirical data in a multivariate context. The structure and parameters were learned with the bnlearn package in R language introducing prior knowledge. The Markov blanket was considered to find those features (variables) which increase the risk of T2D.

Results

The BN model established the different relationships among features (variables). Through inference, a high estimated probability value of T2D was obtained when the body mass index (BMI) was instantiated to obesity value, the glycosylated hemoglobin (HbA1c) to more than 6 value, the fatty liver index (FLI) to more than 60 value, physical activity (PA) to no state, and age to 48–62 state. The features increasing T2D in specific states (warning factors) were ranked.

Conclusion

The feasibility of BNs in epidemiological studies is shown, in particular, when data from T2D risk factors are considered. BNs allow us to order the features which influence the most the development of T2D. The proposed BN model might be used as a general tool for prevention, that is, to improve the prognosis.
Health behaviors and subsequent mental health problems during the COVID-19 pandemic: A longitudinal analysis of adults in the UK
Authors: Russell Jonsson Kenisha , Taylor-Robinson David C. , Schultz Straatmann Viviane , Melis Gabriella , Adjei Nicholas Kofi
Published: January 2023

Introduction

Public health mitigation policies aimed at slowing the spread of COVID-19 led to an increase in mental health problems (MHPs). This study examines the association between multiple pre-pandemic health behaviors and MHPs prior to, and during, the COVID-19 pandemic.

Methods

We analyzed a representative population sample of 11,256 adults (aged 20–65 years) from Understanding Society—The UK Household Longitudinal Study. Baseline data from participants interviewed in 2017/2019 (wave 9) were linked to web surveys conducted during the COVID-19 pandemic. We used latent class analysis (LCA) to identify mutually exclusive health behavior (physical activity, alcohol consumption, eating habits and smoking tobacco) clusters by gender, and examined the sociodemographic correlates of each cluster. We assessed how pre-pandemic latent classes of health behaviors were associated with changes in MHPs during the pandemic using fixed effects regression models.

Results

Three health behavior clusters were identified: positive (33%), moderate (24%), and high risk (43%), where similar behaviors clustered within individuals and sociodemographic circumstances. In particular, gender, age, migrant status and ethnicity were found to have strong associations with each cluster. Our results also demonstrated a clear association in MHPs with health behaviors both prior to, and during the pandemic. There were significant increases in MHPs between 2017/2019 and January 2021, with fluctuations coinciding with changes in public health mitigation policies. Assessments across the three clusters showed about 25.2%, 16.9%, and 0.7% increases in MHPs in the positive, moderate and high risk health behavior clusters, respectively.

Discussion

This study shows that pre-pandemic health behaviors were significantly associated with mental health before and during the pandemic. Holistic policy interventions and promotions targeting multiple health behaviors may be an effective strategy to improve mental health in the pandemic recovery period.
The provision and utilization of essential health services in Afghanistan during COVID-19 pandemic
Authors: Neyazi Narges , Lindan Christina , Perdes Saber , Ibrahimi Abdul Ghani , Horemans Dirk , Al Afsoor Deena
Published: January 2023

Introduction

The COVID-19 pandemic has disrupted provision of essential health services and overwhelmed even robust health systems worldwide. The Afghanistan health system has suffered both from the pandemic, as well as from political upheaval and regime change.

Methods

We evaluated essential service delivery using data collected from a cross-sectional survey of health care facilities in Afghanistan based on administration of a World Health Organization standardized assessment of frontline service readiness. A multi-stage sampling scheme was used to identify a representative sample of 92 health facilities (68 clinics and 24 hospitals) providing essential health services in five provinces. Facility managers were asked to report on changes in health service delivery in late 2021 and early 2022 (corresponding to the end of a significant national COVID-19 surge in infections) compared to the same period one year earlier.

Results

Among health facilities evaluated; 29 were in urban and 63 were in rural settings. Most facilities reported an increase in the provision of outpatient care particularly in maternal and child health services as well as for tuberculosis, chronic respiratory diseases, mental health, and substance abuse; the number of in-patients also increased. In contrast, provision of services for malaria, neglected tropical diseases, and community outreach programs decreased. Nearly all facilities used strategies to maintain services, including targeting high-risk patients, promoting self-care, and redirecting patients to alternative health care sites. Nearly three fourth (70.6%) of facilities provided no training about COVID-19 to staff; only 65.2% referred COVID-19 patients to designated hospitals and 44.6% had safe transportation for these patients.

Discussion

Increased demand for services during this period was likely due to a backlog in need generated during the preceding COVID-19 surge and the political changes happened a few months earlier to this survey. Facilities used various methods to maintain services, although the decrease in provision of community outreach was concerning. Facilities appeared to be able to maintain essential health services, despite an increase in demand. However, awareness and training of COVID-19 protocols and appropriate and safe referrals need to be improved. In general, these series of surveys are informative and helpful to identify any changes in provision of essential health services and can facilitate recovery of health systems during and after pandemics.
Perceptions of COVID-19 among frontline health workers in Burkina Faso
Authors: Yaya Bocoum Fadima , Kadio Kadidiatou , Some Télesphore , Ouedraogo Adidjata , Drabo Maxime , Kouanda Seni
Published: January 2023

Introduction

In Burkina Faso, the first cases of COVID-19 were reported in March 2020. Health personnel are on the front line of COVID-19 control, and it is important to understand their perceptions and knowledge of the disease. The objective was to determine the knowledge and perceptions of healthcare personnel of COVID-19 in the city of Ouagadougou.

Method

The study was conducted in five plots in the city of Ouagadougou. A total of 20 health workers from public and private health centers in the city of Ouagadougou were selected during May 2020. In-depth individual interviews were conducted, and a thematic analysis was performed using NVIVO.

Results and discussion

The routes of transmission identified were promiscuity, respiratory tract, and physical contact. Various symptoms have been noted, such as fever, cough, and runny nose. However, they recognize that these symptoms are not sufficient to make a diagnosis of COVID-19. Similarly, the treatments mentioned are modern medicine and phytomedicine.

Conclusion

The research has generated information on healthcare workers' knowledge and perceptions of COVID-19. Therefore, they are useful for decision-making regarding protective measures for health workers in the management of COVID-19.
A prediction model for the 5-year, 10-year and 20-year mortality of medullary thyroid carcinoma patients based on lymph node ratio and other predictors
Authors: An Yanhua , Lu Jingkai , Hu Mosheng , Cao Qiumei
Published: January 2023

Aim

To explore the predictive value of lymph node ratio (LNR) for the prognosis of medullary thyroid carcinoma (MTC) patients, and constructed prediction models for the 5-year, 10-year and 20-year mortality of MTC patients based on LNR and other predictors.

Methods

This cohort study extracted the data of 2,093 MTC patients aged ≥18 years undergoing total thyroidectomy and neck lymph nodes dissection. Kaplan-Meier curves and log-rank tests were performed to compare survival curves between LNR < 15% group and LNR ≥ 15% group. All data was divided into the training set (n = 1,465) and the testing set (n = 628). The random survival forest model was constructed in the training set and validated in the testing set. The area under the curve (AUC) was employed for evaluating the predictive ability of the model.

Results

The 5-year, 10-year and 20-year overall survival (OS) and cause-specific survival (CSS) of MTC patients with LNR <15% were higher than those with LNR ≥15%. The OS was 46% and the CSS was 75% after 20 years' follow-up. The AUC of the model for the 5-year, 10-year, and 20-year OS in MTC patients was 0.878 (95%CI: 0.856–0.900), 0.859 (95%CI: 0.838–0.879) and 0.843 (95%CI: 0.823–0.862) in the training set and 0.845 (95%CI: 0.807–0.883), 0.841 (95%CI: 0.807–0.875) and 0.841 (95%CI: 0.811–0.872) in the testing set. In the training set, the AUCs were 0.869 (95%CI: 0.845–0.892), 0.843 (95%CI: 0.821–0.865), 0.819 (95%CI: 0.798–0.840) for the 5-year, 10-year and 20-year CCS in MTC patients, respectively. In the testing set, the AUCs were 0.857 (95%CI: 0.822–0.892), 0.839 (95%CI: 0.805–0.873) and 0.826 (95%CI: 0.794–0.857) for the 5-year CCS, 10-year CCS and 20-year CCS in MTC patients, respectively.

Conclusion

The models displayed good predictive performance, which might help identify MTC patients might have poor outcomes and appropriate interventions should be applied in these patients.
Quantitative systems modeling approaches towards model-informed drug development: Perspective through case studies
Authors: Verma Meghna , Gall Louis , Biasetti Jacopo , Di Veroli Giovanni Y. , Pichardo-Almarza Cesar , Gibbs Megan A. , Kimko Holly
Published: January 2023

Quantitative systems pharmacology (QSP) modeling has become an increasingly popular approach impacting our understanding of disease mechanisms and helping predict patients’ treatment responses to facilitate study design or development go/no-go decisions. In this paper, we highlight the notable contributions and opportunities that QSP approaches are to offer during the drug development process by sharing three examples that have facilitated internal decisions. The barriers to successful applications and the factors that facilitate the success of the modeling approach is discussed.
Effects of dietary fermented peony seed dreg on the laying performance, albumen quality, antioxidant capacity, and n-3 PUFA-enriching property of laying hens
Authors: Wan Yi , Ma Ruiyu , Qi Renrong , Lu Jing , Wang Zaigui , Ma Qiugang , Liu Wei , Li Junying , Li Yan , Zhan Kai
Published: January 2023

Introduction

It is of great importance to seek agro-industrial byproducts that can serve as unconventional or alternative feedstuffs for poultry, especially those that are substitutive sources of n-3 polyunsaturated fatty acids (PUFAs), as this will contribute to alleviating feed shortage pressure and improving poultry performance and product quality. In this study, the effects of dietary fermented peony seed dreg (FPSD) on the production performance of hens and fatty acid composition of meat and egg yolk were evaluated.

Methods

A total of 480 54-week-old Xinyang chickens were divided into 5 groups: control (basal diet); 5% peony seed dreg (PSD); and 5%, 7% and 9% FPSD, and each group consisted of 6 replicates with 16 birds per replicate. Production performances were recorded daily, and egg quality, serum parameters, antibody titers and fatty acid profile in the muscle and yolk were measured at 64 weeks of age.

Results and discussion

Egg production, feed conversion ratio and egg albumen quality were improved (p < 0.05) by 5% and 7% FPSD groups compared to 5% PSD and the control diet. Immune status was not influenced by PSD, but antibody titres against H7N9 and ND were improved by FPSD diets during most of the experimental periods. Dietary 5% and 7% FPSD increased (p < 0.05) serum high density lipoprotein concentrations and glutathione peroxidase actives. Total n-3 polyunsaturated fatty acids (PUFA) in meat and yolk increased gradually, while the total saturated fatty acids (SFA) and the n-6/n-3 PUFA ratio decreased gradually with increasing dietary FPSD levels. In conclusion, up to 7% dietary FPSD has the potential use to be utilized as a supplement in Xinyang laying hen diets to produce n-3 PUFA-enriched meat and eggs and positively affect production performance and health status.
Numerical Simulations on the Performance of Two-Dimensional Serpentine Nozzle: Effect of Cone Mixer Angle and Aft-Deck
Authors: Ahmed Hamada Mohmed Abdelmotalib , Ahn Byung-Guk , Lee Jeekeun
Published: January 2023

The current study addresses the effect of different designs of the exhaust mixer and aft-deck on the performance of a two-dimensional convergent nozzle represented by the internal and external flows and heat transfer process. The effect of different exhaust mixer cone angles of 10°, 15°, and 20°, and different aft-deck lengths of 140 mm, 280 mm, and 420 mm on the nozzle performance was investigated. To address the effect of an aft-deck, the flow behavior of a nozzle with an aft-deck was compared to that of a nozzle without an aft-deck. Then, the effect of different aft-deck lengths and different aft-decks with rectangular and trapezoid shapes was investigated. The results demonstrated that increasing the mixer cone angle resulted in decreasing the high-temperature core flow and increasing the low-temperature bypass flow. Increasing the mixer cone angle resulted in reducing the velocity inside the nozzle and at the exhausted jet, which can reduce the noise generated by the engine. Furthermore, increasing the mixer cone angle decreased the internal temperature of the nozzle and, along with the exhausted jet, decreased the infrared radiation. The results also illustrated that the presence of the aft-deck resulted in decreasing the pressure, temperature, and velocity inside the nozzle. The aft-deck also decreased the length and size of the potential core. The aft-deck length had no clear effect on the internal flow. However, increasing the aft-deck length resulted in a decrease in the exhaust gas temperature, which can decrease the infrared radiation. On another hand, using trapezoid and triangle aft-deck can enhance the performance of the nozzle by decreasing the velocity and temperature inside the nozzle and at the exhausted jet.
Comparative Biochemical and Transcriptome Analyses Reveal Potential Candidate Genes Related to Pericarp Browning in Red Rice
Authors: Lee Gileung , Park Jae Wan , Park Jisu , Han Ah-Reum , Hong Min Jeong , Jo Yeong Deuk , Kim Jin-Baek , Kim Sang Hoon , Choi Hong-Il
Published: January 2023

Proanthocyanidins (PAs) are major phytochemicals in rice, and accumulate abundantly in red pericarp (RP) rice. Consumers and rice breeders are increasingly showing interest in PAs because of their beneficial health effects; however, PA biosynthesis in rice is not well-understood. Therefore, to gain insights into this process, we performed comparative transcriptome analysis of grains harvested at 14 days after flowering (DAF; i.e., the stage at which active PA biosynthesis occurs without pericarp color change) and 28 DAF (the stage of late seed development with pericarp color change) from RP and white pericarp rice. In RP rice at 14 DAF, the expression levels of six structural genes (OsCHS, OsF3H, OsF3′H, OsDFR, OsANS, and OsLAR), one modification gene (OsUGT), and one transport gene (OsGSTU34) were significantly upregulated, along with the activation of Rc, the key regulator of PA accumulation in the pericarp. Functional enrichment analysis of 56 differentially expressed genes specifically upregulated in RP rice at 28 DAF revealed the presence of three laccase genes known to cause the browning reaction through oxidation. These results expand our understanding of PA biosynthesis in rice, and provide a genetic basis that will lead to further studies on the genes and underlying molecular mechanisms associated with this process.
Effect of Length of Storage and Chemical Additives on the Nutritive Value and Starch Degradability of Reconstituted Corn Grain Silage
Authors: Oliveira Késia da Silva , Salvati Gustavo Gonçalves de Souza , Morais Greiciele de , Carvalho-Estrada Paula de Almeida , Santos Willian Pereira dos , Salvatte Jéssica Mariane Silveira , Gritti Viviane Carnaval , Salvo Pedro Augusto Ribeiro , Arthur Bruno Augusto Valverde , Nazato Larissa Maniero , Nussio Luiz Gustavo
Published: January 2023

The aim of this study was to evaluate the feed quality of reconstituted corn grain silage (RCGS), treated with chemical additives and stored for 15, 30, or 60 d in 5-L plastic buckets. Dry ground corn was rehydrated to 350 g·kg−1 and treated with either polysorbate 80 (2 L·t−1) (POL), propionic acid 28% (2 L·t−1) (PRO), Mycoflake™ (2 L·t−1-blend polysorbate 80 and propionic acid) (MYC) or nothing (CON). The effect of the length of storage was combined in a factorial arrangement with the additives. Ammonia-N increased from d-15 of storage. A treatment × storage length interaction was observed for ethanol content at d-60 of storage, and all treatments had lower ethanol concentration than CON. There was an interaction for butyric acid content at d-30 and d-60 of storage; CON showed higher butyric acid concentration than treated silages. Aerobic stability increased from d-15 to d-30. At d-15 of storage, the PRO and MYC treatments decreased the DM losses. The length of storage increased the ruminal in situ degradability of starch, and DM and MYC increased the DM degradability in 3.6 percentage units at 12 h of incubation, compared with POL. In conclusion, increasing the length of storage of the RCGS from d-15 to d-60 improved the starch and DM degradability. Mycoflake increased the availability of nutrients, and the length of storage enhanced the aggregation of particles; further, polysorbate 80 (Tween 80) might be further studied as a potential antimicrobial agent in silages.
Overcoming Challenges for Shoot Tip Cryopreservation of Root and Tuber Crops
Authors: Zhang A-Ling , Wang Min-Rui , Li Zhiying , Panis Bart , Bettoni Jean Carlos , Vollmer Rainer , Xu Li , Wang Qiao-Chun
Published: January 2023

Root and tuber crops (RTCs) are the second-most important carbohydrate commodity after cereals. Many species of the RTCs are vegetatively propagated, making their shoot tips the preferred material to be conserved for future uses. Shoot tip cryopreservation provides an important tool to support the long-term conservation of plant genetic resources. Over the past four decades, significant efforts have been undertaken to move shoot tip cryopreservation of RTCs from research projects to full-scale implementation in cryobanks. This comprehensive review focuses on the history of cryopreservation protocols developed in RTCs. The encapsulation and vitrification solution-based cryopreservation techniques followed by ultra-rapid freezing and thawing have been highly successful. Additionally, different strategies for improving the cryotolerance of shoot tips have been introduced to further increase post-cryopreservation recovery. Finally, the research conducted to explain the mechanism underlying cryoprotection and differential cryotolerance including the use of histological studies are highlighted.
Rhizosphere Microbial Community Shows a Greater Response Than Soil Properties to Tea (Camellia sinensis L.) Cultivars
Authors: Wei Sirou , Liu Boheng , Ni Kang , Ma Lifeng , Shi Yuanzhi , Leng Yang , Zheng Shenghong , Gao Shuilian , Yang Xiangde , Ruan Jianyun
Published: January 2023

Rhizosphere microbes play pivotal roles in regulating the soil ecosystem by influencing and directly participating in the nutrient cycle. Evidence shows that the rhizosphere microbes are highly dependent on plant genotype and cultivars; however, their characteristics in soils with different tea (Camellia sinensis L.) cultivars are poorly understood. Therefore, the present study investigated the rhizosphere soil properties, microbial community composition, and their potential functions under four tea cultivars Huangjinya (HJY), Tieguanyin (TGY), Zhongcha No.108 (ZC108), and Zijuan (ZJ). The study found a minor impact of cultivars on rhizosphere soil properties but a significant influence on microbial community structure. Except for available potassium (AK) (HJY > TGY > ZC108 > ZJ), tea cultivars had no significant impact on other soil properties. The tea cultivars resulted in substantial differences only in the diversity of soil bacteria of lower taxonomic levels (family to species), as well as significantly changed communities’ structure of bacteria and fungi (R2 = 0.184, p = 0.013 and R2 = 0.226, p = 0.001). Specifically, Proteobacteria, Actinobacteria, Chloroflexi, Acidobacteriota, and Firmicutes accounted for approximately 96% of the bacterial phyla in the tea soils, while Ascomycota, Mortierellomycota, Rozellomycota, Basidiomycota, and Monoblepharomycota (90% of the total) predominated the soil fungal community. Redundancy analysis (RDA) identified soil pH (14.53%) and ammonium-nitrogen (NH4+-N; 16.74%) as the key factors for the changes in bacterial and fungal communities, respectively. Finally, FAPROTAX analysis predicted significant differences in the carbon, nitrogen, and sulfur (C-N-S)-cycling among the soils with different tea cultivars, specifically, ZJ cultivar showed the highest C-cycling but the lowest N- and S-cycling, while FUNGuild analysis revealed that the pathotroph group was significantly lower in ZC108 than the other cultivars. These findings improve our understanding of the differences in microbial community characteristics among tea cultivars and provide a basis for precisely selecting and introducing excellent tea varieties in the agriculture practices.
The Effects of Short-Time Delayed Sealing on Fermentation, Aerobic Stability and Chemical Composition on Maize Silages
Authors: de Melo Natália Nunes , Carvalho-Estrada Paula de Almeida , Tavares Queila Gouveia , Pereira Lucelia de Moura , Delai Vigne Gabriela Leticia , Camargo Rezende Douglas Messias Lamounier , Schmidt Patrick
Published: January 2023

Despite the efforts to improve the methodological standards of silage trials, many factors that can influence the results of lab-scale studies need to be better understood. This study aimed to determine the effects of short-time delayed sealing and inoculation with a blend of Lentilactobacillus buchneri and Lactiplantibacillus plantarum on fermentation, aerobic stability, and chemical composition of silages. Whole-crop maize was treated with or without a commercial inoculant and ensiled (29.3% dry matter) for 55 days in 8.8 L PVC silos that were sealed immediately (up to 30 min delay) or after a delay (90, 150, or 210 min between chopping and sealing) with five replicates each. The increasing air exposure before sealing increased fermentation losses and reduced silage nutritional value. Crude protein and ash were significantly affected by inoculation, with control treatments showing higher ash and lower protein values. Lignin, neutral detergent fiber, and acid detergent fiber were only affected by the delay period. The longer the sealing delay, the higher the gas production, and the lower the starch values and lactic acid content observed in samples. Inoculation was inefficient in reducing total dry matter losses, but it increased aerobic stability, acetic acid, and ethanol contents of silages and reduced effluent loss. Control silages had higher total dry matter loss during the aerobic exposure than inoculated silages. The results confirmed that the delay periods tested were long enough to negatively interfere with the chemical composition of silages, especially the fibrous fraction content.
Survey of Zoonotic Diarrheagenic Protist and Hepatitis E Virus in Wild Boar (Sus scrofa) of Portugal
Authors: Santos-Silva Sérgio , Moraes Danny Franciele da Silva Dias , López-López Pedro , Palmeira Josman D. , Torres Rita T. , São José Nascimento Maria , Dashti Alejandro , Carmena David , Rivero-Juarez Antonio , Mesquita João R.
Published: January 2023

Enteropathogenic parasites and viruses have been frequently reported in swine and can infect a wide range of mammals, including humans. Among the wide variety of parasites infecting swine, diarrhoeagenic protists are among those that cause significant morbidity. Hepatitis E virus (HEV) has also been reported both in domestic pigs and wild boar and is known to have an important public health significance. These agents share the fecal–oral transmission route, but data on their fecal shedding and circulation pathways are still lacking or incomplete. Hence, the aim of the present study was to characterize the presence of microeukaryotes and HEV in the wild boar of Portugal. Wild boar stool samples (n = 144) were obtained during the official hunting seasons (October to February) in 2018/2019, 2019/2020, and 2021/2022 and tested for Cryptosporidium spp., Balantioides coli, Giardia duodenalis, Blastocystis sp., Enterocytozoon bieneusi and HEV by molecular assays, followed by sequencing and phylogenetic analysis. We have detected Cryptosporidium scrofarum (1.4%, 95% CI: 0.2–4.9), B. coli (14.6%, 95% CI: 9.2–21.4), Blastocystis ST5 (29.2%, 95% CI: 21.9–37.2) and HEV genotype 3 (2.8%, 95% CI: 0.7–6.9; subgenotypes 3e and 3m). Co-infections were observed in thirteen animals where two were positive for both HEV and B. coli, one was positive for both C. scrofarum and Blastocystis ST5, and ten were positive for both B. coli and Blastocystis ST5. Giardia duodenalis and E. bieneusi were not detected in the surveyed wild boar population. As far as we know, this is the first report describing protist infections by Cryptosporidium spp., B. coli, and Blastocystis sp., as well as the first identification of the emerging HEV genotype 3m in wild boar of Portugal. The present work shows that potentially zoonotic protozoa and HEV are circulating in wild boar populations in Portugal. Awareness and epidemic-surveillance network implementation measures targeting wild boar are needed to prevent the spread of these pathogenic agents to humans.
Serum Anti-Müllerian Hormone Levels and Estrous Monitoring of GnRH Agonist Deslorelin-Induced Estrus in Bitches: A Pilot Study
Authors: Chotimanukul Sroisuda , Goericke-Pesch Sandra , Suwimonteerabutr Junpen , Singlor Jinda , Sangkrachang Ekkaphot , Tummaruk Padet , Ponglowhapan Suppawiwat
Published: January 2023

This study was performed to monitor estrous patterns and, more importantly, changes in anti-Müllerian hormone (AMH) concentrations during the peri-ovulatory period in deslorelin-induced estrous bitches. Healthy anestrous bitches (n = 4) were used. Estrus and ovulation were monitored after deslorelin implantation. Blood samples were collected for analysis of progesterone, estradiol-17ß and AMH concentrations before implantation (day 0) and on days 6, 8, 10, 12, 14, 16, 18, 20 and 22 after implantation. Six days following treatment, all bitches showed estrus signs. Ovulation took place between days 12 and 15. Circulating AMH concentrations varied among bitches from 0.12 to 3.08 ng/mL. However, no significant differences in AMH levels (mean ± SD) were observed between day 0 and days following post-implantation (p > 0.05). There were no significant correlations between AMH and estradiol or AMH and progesterone (p > 0.05). Ultrasonographically, the number of clearly identifiable ovarian follicles was higher before ovulation and the area of ovaries increased after ovulation (p < 0.05). Except for AMH, changes in vaginal cytology, estradiol-17ß and progesterone levels observed in our study were similar to naturally occurring estrus. Large intra- and inter-individual variation in AMH were observed suggesting that AMH is currently not suitable as a canine fertility marker to monitor ovarian response to deslorelin treatment for estrus induction.