bluuebunny/crossref_metadata_2025 huggingface dataset:
JURIDICAL REVIEW MOTOR VEHICLE NOISE THRINGS IN INDONESIA'S POSITIVE LAW
Authors: Suparyo  , Ardiansyah  , Bagio Kadaryanto
Published: July 2022

As referred to in Article 106 paragraph (3) in conjunction with Article 48 paragraph (2) and paragraph (3) shall be sentenced to a maximum imprisonment of 1 (one) month or a maximum fine of Rp. 250,000.00 (two hundred and fifty thousand rupiah). As for the formulation of the problem in this study is HowMean Motor Vehicle Noise Threshold, HowJuridical Overview Motor Vehicle Noise Threshold, and HowLegal SettlementMotor Vehicle Noise Threshold in Indonesian Positive Law. The method used is normative legal research. Data sources consist of primary legal materials, secondary legal materials, and tertiary legal materials. In this study the data were analyzed qualitatively and in drawing conclusions the authors applied the method of deductive thinking. Based on the results of the study it is known thatMean Motor Vehicle Noise Threshold that is in the Regulation of the State Minister of the Environment Number 7 of 2009 concerning the New Type Motor Vehicle Noise Threshold. In the attachment of the Minister of Environment Regulation Noise Threshold confirms that the motorcycle noise threshold under 175cc is 80 dB and above 175cc is 83 dB.Juridical Overview Motor Vehicle Noise Threshold that in Article 285 of Law Number 22 of 2009 concerning Road Traffic and Transportation paragraph (1) that everyone who drives a Motorcycle on the Road that does not meet the technical and road-worthy requirements which includes rearview mirrors, horns , headlights, brake lights, directional lights, reflecting devices, speed measuring devices, exhaust, and tire groove depth as referred to in Article 106 paragraph (3) in conjunction with Article 48 paragraphs (2) and (3) shall be punished with imprisonment for a maximum of 1 (one) month or a maximum fine of Rp. 250,000.00 (two hundred and fifty thousand rupiah). Legal SettlementMotorized Vehicle Noise Threshold In Indonesian Positive Law that in taking action by law enforcement in this case the police and the Transportation Agency in carrying out enforcement in terms of noise testing, they never test how much noise is produced and law enforcers do not have the tools to measure the noise level generated from exhaust of motorized vehicle users on the highway.
THE LEGAL POWER OF THE AUTHENTICITY OF BIPARTITE JOINT AGREEMENT BETWEEN PT PLATINUM CERAMICS INDUSTRY SURABAYA AND WORKERS
Authors: Riawanto Riawanto , Harianti Isnin , Rohmah Mayza H
Published: July 2022

The aim of research is To know the executory power attached to an Act (written proof) and Conducting a legal analysis of a BIPARTITE PB registered with PHI, so that it can be executed appropriately if there is an act of default. The method used is normative juridical law research, which essentially examines laws that are conceptualized as norms or rules that apply in society. The result showed that Notaries play a role in carrying out some of the authority or duties of the state in the civil domain, and are referred to as general officials who are authorized to make AO which is a manifestation of the wilsvorming of the parties, made before a notary or by a notary.
ANALYSIS OF THE IMPLEMENTATION OF AREA ENTRY PERMITS (SIMA) IN AN EFFORT TO IMPROVE EMPLOYEE PERFORMANCE AT PERTAMINA EP CEPU'S JTB GAS DRILLING PROJECT
Authors: Hidayat Ahmad , Paizal Andi
Published: July 2022

Many work accidents are caused by undisciplined in the use of PPE (Personal Protective Equipment), not complying with standard procedures, and using the wrong machine and equipment. The purpose of this study is to analyze and evaluate SIMA implementation in the JTB-PEPC Gas drilling project, and using qualitative research methods with data collection techniques of observation, interviews, and documentation. The results of this study show that the SIMA implementation to improve employee performance in the JBT-PEPC Gas drilling project has been running Process by producing faster drilling times than the target and can reduce the number of work accidents, but in SIMA implementation there are still some findings that have not been maximized, because they are still found violations that can affect employee performance will cause work accidents and employee discipline is still low in the use of PPE.
IMPLEMENTATION OF STATE PROPERTY MANAGEMENT POLICY AT THE SECRETARIAT GENERAL OF THE GENERAL ELECTION SUPERVISORY AGENCY REPUBLIC OF INDONESIA
Authors: Ahmad Hidayat  , Fahdrian Kemala
Published: July 2022

Implementation of policies on the management of state goods at the Secretariat General of the General Elections Supervisory Agency of the Republic of Indonesia. The purpose of this study was to determine and evaluate the implementation of policies on the management of state property in the General Secretariat of the General Elections Supervisory Agency. The theory used as a reference is the theory of George C. Edward III which states that there are four things that affect the implementation of policies, namely communication, resources, disposition and structure of the bureaucracy. This study uses a qualitative method with eleven informants consisting of officials/employees in the Secretariat General of the General Elections Supervisory Agency and the Provincial General Elections Supervisory Agency, officials within the Ministry of Finance and members of the working group of the Government Accounting Standards Committee. Based on the results of the research, it is known that the implementation of the policy on the management of state property within the Secretariat General of the General Elections Supervisory Agency has not gone well. The factors that influence the implementation of the policy are communication, resources, disposition and bureaucratic structure. The inhibiting factors are resources, disposition and bureaucratic structure, while communication does not become an obstacle in implementing state property management policies at the Secretariat General of the General Elections Supervisory Agency.
INFLUENCE OF SERVICE QUALITY AND OPERATIONAL STANDARD OF SERVICE PROCEDURES (SOP) ON SATISFACTION OF COMMUNITY AT ONE-STOP SERVICE IMPLEMENTING UNIT SUB DISTRICT GUNUNG SAHARI UTARA
Authors: Tuswoyo  , Kartika Methasari
Published: July 2022

The purpose of this research is to know the influence of service quality and operational standard of service procedures (SOP) to public satisfaction at One-Stop Service Implementing Unit Sub District Gunung Sahari Utara. This research is a quantitative field research. Field research is a study to obtain data that actually occurs in the field. While quantitative means to emphasize the analysis of numerical data (numbers) obtained by statistical methods. The method used in this research is Survey research method. The population in this study were all applicants who used the services of One-Stop Service Implementing Unit Sub District Gunung Sahari Utara, taken based on the average number of visitors per month (period September - October 2017). So the sample in this study is as many as 271 people. The sampling technique used in this research is convenience/accidental sampling. Based on the result of F test analysis known that the value of F count 41.304, and with the level of significance (p-value), 0.000. This means that the value of Sig<value of (0.000 < 0.05), it can be concluded that Service Quality (X1) and Standard Operational Procedure Service (X2) together have a very significant effect on Satisfaction of society (Y). The result of Determination Coefficient analysis is known that the influence between Quality of service (X1) and Standard Operational Procedure Service (X2) on Satisfaction of society (Y) obtained coefficient of determination equal to 0.236. This implies that about 23.6% of the variations occurring in Community Satisfaction in the One-Stop Service Implementing Unit Sub District Gunung Sahari Utara can be explained by Quality of Service and Standard Operational Procedure of Service.
IMPLEMENTATION OF UNLIMITED DENTAL SUPERVISION
Authors: Teti Sutriani  , Montisa Mariana  , Irma Maulida
Published: July 2022

Since the beginning of January 2013, the number of registered dental professionals is ± 75,000. There are still many dental artisan practices indicating that our society is interested in dental services. The legal basis for dental work has been regulated by the government, in this case the Ministry of Health issued Permenkes No. 53/DPK/1/K/1969 and Permenkes No. 339/MENKES/PER /V/1989 on dental work. The regulation regulates the authority, prohibition and licensing of dental artisans.In Indonesia, dental technicians who carry out dental work are required to register with the district/city government or the local district/city health office to obtain a dental technician's license. The dental technician's license is valid for two years and can be extended as long as it meets the requirements.Research with approach methodnormative juridical, namely the method of collecting data by conducting a literature review associated with problems as mentioned above. Based on the results of the research, dentists who carry out dental work without having a dental technician's license and work outside their authority can be subject to sanctions based on the Medical Practice Act article 73 paragraph (2). the person concerned is subject to sanctions. If the patient feels aggrieved by the services provided by the dental artisan, the patient can claim compensation. The Cirebon City Health Office has not carried out periodic supervision of dental artisans in the city of Cirebon. This is because there are obstacles in the workforce (HR) to carry out such supervision.
NORMATIVE TEST FOR ENFORCEMENT OF COLONIAL LAW AND MORAL JUSTICE ARTICLE OF CONTROVERS IN THE NATIONAL KUHP BILL
Authors: Waluyadi
Published: July 2022

Indonesia is an independent country. In criminal law it is still colonized. At first, the implementation of the colonial Criminal Code (KUHP) was only temporary. The law has legalized the adjustment of the implementation of the colonial Criminal Code in the spirit of an independent and sovereign state. I just don't have the courage to do it. The plan to stipulate the original Indonesian Criminal Code was met with demonstrations. In this paper, the problem that will be revealed is what is the normative measure of the enforcement of the colonial Criminal Code in Indonesia and how is the moral justice of the controversial articles in the National Criminal Code Bill. This paper is sourced from normative research. The data used is secondary data. Data collection was carried out by means of a literature study, The data were analyzed qualitatively and presented in descriptive form. From the results of the research, it is known that the Act has legalized the enactment of the colonial Criminal Code in Indonesia, with exceptions. The articles in the Draft Criminal Code which are considered controversial have already accommodated moral values.
3F. COLLEGE LES CAMPELIERES
Authors: PLAKSIN Makarii
Published: July 2022

The purpose of the research is to study the process of learning in French colleges based on the written record of works of personal origin (on the basis of the LES CAMPELIÈRES college). Research methodology includes the following main methods: survey method, comparative, induction and deduction, descriptive, generalization. Thanks to this, the work traces its own logic of thinking, characteristic of each generation, regarding the education system in France. The scientific novelty consists in the use of interdisciplinary connections of the study based on the subjectivity of the relations of the participants in the learning process. The work presents memories of college teachers, 3rd grade students and their parents. Conclusion. The LES CAMPELIÈRES Class 3 F Graduate Book contains memoirs of the learning atmosphere, verbal evaluations of the teaching aids used in the educational establishment. The work with the class was evaluated by the teachers: Virginie RABAUTE, Caroline DUCH, Laurie PETITGIRARD, Céline BRIGHIGNI DE BUSTOS. The material of the Book can be used in research on the theory and practice of teaching in France, the history of education. The research is not exhaustive and involves the accumulation of material for analysis, systematization and formulation of conclusions, which is a promising task for those interested.
Continuous Extensions On Euclidean Combinatorial Configurations
Authors:   National Aerospace University ”Kharkiv Aviation Institute”, Ukraine, Pichugina Oksana , Yakovlev Sergiy ,   National Aerospace University ”Kharkiv Aviation Institute”, Ukraine
Published: July 2022

In this paper, we introduce a concept of the Euclidean combinatorial configuration as a mapping of a set of certain objects into a point of Euclidean space. We classify Euclidean combinatorial configurations sets based on their structure and constraints. The proposed typology forms the basis for studying continuous functional representations of combinatorial configurations. Special classes of functional extensions are introduced, their properties are described, and corresponding examples are given.
ANÁLISIS DE LA ELABORACIÓN DE HARINA NO CONVENCIONAL DE ZANAHORIA (DAUCUS CAROTA)
Authors: Ormaza César , Saavedra Vivian
Published: July 2022

El presente trabajo de investigación realizado en la Escuela Superior Politécnica de Chimborazo. tiene como finalidad aportar con nuevas alternativas tanto nutricionales como comerciales de la harina de zanahoria, que utilizándola para la agroindustria pasaría a contribuir al desarrollo económico de nuestro país. Por tal razón este trabajo describe el proceso de análisis de elaboración de harina no convencional de zanahoria, cuyas características son las de una harina muy rico, nutritivo y saludable para quien la consuma; además la utilización de la zanahoria es debido a que es una hortaliza muy poco industrializada motivo por el cual existe un alto porcentaje de desperdicios. Para la determinación del experimento se aplicó un diseño experimental 2k cuyos resultados fueron: temperatura 68°C, tiempo de secado de 8 horas y espesor de rodaja 5 mm. Se realizaron análisis fisicoquímicos, microbiológicos y bromatológicos en la harina, los mismos que se encuentran dentro de los límites establecidos por las normas para harina convencional y para harina no convencional. Además, se determina el aporte nutricional de la harina obteniéndose en carbohidratos rangos aproximados de 73%; fibra 8%; proteína 5%; grasa 2%; azúcares 6%; sodio 164 mg/100g y almidón 28,31%. Se analizaron las propiedades físicas de la zanahoria amarilla relacionándola con su granulometría, para efecto se tomó cinco unidades, las cuales se van separando por fracción hasta que tenga la consistencia de una harina.
Tıbbi Terminolojide Akronimler. Almanca-Türkçe Dil İkilisi Örneği
Authors: TURAN Dilek
Published: July 2022

Tıbbi terminoloji çok eskilere dayanan tarihi bir süreç içerisinde gelişen, günümüze kadar sürekli yenilenen ve gelişim gösteren bir özel alan dilidir. Dolayısıyla dinamik bir yapıya sahiptir ve Tıp alanındaki yeni gelişmelere açık bir yapısı vardır. Tıbbi terminolojide yer alan terimlerin oluşturulma biçimleri çok farklı kaynaklardan ve yapılardan oluşmaktadır. Tıp terimleri çoğunlukla Latince, Yunanca, Arapça ve son yıllarda artan sayıyla da İngilizce kökenli sözcüklerden üretilmektedir. Günümüzde Tıp bilimine (özellikle de patolojiye) yeni yerleşen terimlerde sıkça kısaltmalara (kısma adlara) rastlanmaktadır. Bu kısaltmalar Latince, Yunanca ve özellikle de İngilizce sözcük ve sözcük gruplarının baş harflerinden oluşturulan akronimlerdir. Bu çalışmada akronimlerin diller arasındaki farklılık ve tutarsızlıklarının olduğu Almanca-Türkçe örneğinden yola çıkılarak gösterilmeye çalışılacak ve Tıp metinleri çevirisi için ortaya çıkabilecek sorunlar üzerinde durulacaktır.
Vaterdezentrierungen
Authors: Schmid Rafaela
Published: July 2022

In der Kriegskinderforschung wird die Abwesenheit des biologischen Vaters und das Aufwachsen nur bei der biologischen Mutter als problematisch für die psychische Entwicklung von Kindern postuliert. Der abwesende biologische Vater rückt ins Zentrum, mit ihm steht und fällt die psychische Gesundheit des Kindes.

Rafaela Schmid etabliert eine neue Reflexionsebene im Fachdiskurs um (kriegsbedingte) ›Vaterlosigkeit‹. Sie nähert sich der Problematik exemplarisch mittels einer hermeneutischen Lektüre und Interpretation der Fachliteratur über sogenannte ›Besatzungskinder‹. Darin enthaltene Verkürzungen psychoanalytischer Konzepte werden durch eine Auseinandersetzung mit der Stellung des Vaters in der Theorie Freuds sichtbar, was in der Folge eine Dezentrierung des biologischen Vaters möglich macht. So kann das gängige eindimensionale und von patriarchalen Strukturen bestimmte Narrativ der ›Vaterlosigkeit‹ als Mangelzustand herausgefordert werden.
Informationelle und finanzielle Unabhängigkeit des Aufsichtsrats und seiner Mitglieder
Authors: Vossen Christina
Published: July 2022

This dissertation takes an in-depth look at the many different ways in which a budgetary right for the supervisory board, introduced into the debate on stock corporation law in 2011, could be structured and sheds light on its functional added value with a view to effective supervisory board activity. Based on the urgent need for the supervisory board to be as independent as possible from the executive board in terms of information and finances, a detailed proposal is developed for a budgetary right to be integrated into the German Stock Corporation Act de lege ferenda, which can make a decisive contribution to making supervisory board activities more effective. A topic that is more topical than ever in view of a corresponding legislative initiative.
Versöhnung durch Wahrheit?
Authors: Burkard Hannah Katharina
Published: July 2022

In the context of comparative legal history, the South African Truth and Reconciliation Commission is contrasted with the Study Commission for Working Through the History and the Consequences of the SED Dictatorship in Germany. In an extensive examination, central aspects of the commissions' mandates and their implementation are analyzed, thus providing a deeper understanding of the two truth commissions. Whilst the final reports of the commissions serve as a central source, personal interviews with experts in transitional justice and contemporary witnesses from South Africa are also included in the work.
Big Data and the Abuse of Dominance by Multi-Sided Platforms
Authors: Cyriac Noby Thomas
Published: July 2022

The author thoroughly examines the ability of Art.102 TFEU to protect competition against the abusive conduct by dominant platforms in an interdisciplinary manner. The initial part of the study clarifies the fundamentals of digital economy, especially Big Data and multi-sided platforms. The subsequent part elaborates on the relevant concepts that have been developed by the Commission and EU Courts in their decision-making practice on the interpretation of Art.102 TFEU, so as to assess their suitability for the prohibition of abuse by platform operators in the light of the intricacies of multi-sided markets. The existence and delimitation of a data market has also been innovatively discussed.
A New and Cost-Effective Approach to Risk Stratification for Children with Precursor B-Cell Acute Lymphoblastic Leukemia Based on Competing Outcomes
Authors: Bonakchi Hossein , Kuhestani Dehaghi Bentolhoda , Hosseini-Baharanchi Fatemeh Sadat , Parkhideh Sayeh , Farhangi Hamid , baghestani Ahmad reza
Published: July 2022

Background: Acute lymphoblastic leukemia (ALL) is a malignancy of the white blood cells characterized by its rapid and aggressive progress that needs immediate treatment. ALL could affect both adults and children. Various patient- and disease-related factors may be involved in ALL patients’ prognosis. Therefore, it is critical to identify important risk factors related to the competing outcomes of patients with ALL. Objectives: This study aimed to stratify the risk of outcomes of children with precursor B-cell ALL using demographic characteristics, laboratory characteristics, and extramedullary diseases. To achieve this goal, we used the best competing risks model to make an appropriate decision for children's treatment according to this classification. Methods: In this retrospective cohort study, 393 patients with ALL were included. ALL with B cell origins (CD20, CD19, CD10, and CD22 positive markers) was differentiated using flow cytometry. Complete remission was defined by a lymphoblast count of less than 5% in the bone marrow, presence of no blasts in cerebrospinal fluid (CSF), as well as complete disappearance of clinical symptoms. Patients with ALL were treated based on Berlin-Frankfurt-Münster (BFM). Competing outcomes were first-relapse and non-relapse mortality, respectively. Risk factors affecting competing outcomes were assessed based on a fully specified sub-distribution model. Results: Five-year estimates for overall survival and event free survival were 75% (95% CI: 69 - 79%) and 71% (95% CI: 66 - 75%), respectively. Five-year incidence rates for first-relapse and non-relapse mortality in children were 11.4% (95% CI: 8.32 - 15.16%) and 17.6% (95% CI: 13.98 - 21.67%), respectively. Moreover, according to the results, children with WBC > 50000, hemoglobin 8, and tumor lysis syndrome for the first-relapse outcome, and children with central nervous system (CNS) involvement and tumor lysis syndrome for the non-relapse mortality (NRM) outcome were considered as high-risk groups. Conclusions: We found that extramedullary diseases could have a crucial role in the risk stratification of children with precursor B-cell ALL. Therefore, for a targeted and effective treatment of high-risk children, in addition to chemotherapy, using appropriate PI3K pathway inhibitors, JAK2 pathway inhibitors, and antibody-based immunotherapy is recommended to reduce minimal residual disease and, consequently, mortality rate.
The “Effect of Marangoni convection on heat transfer in Phase Change Materials” experiment, from a student project to the International Space Station
Authors: Salgado Sánchez Pablo , Ezquerro Jose Miguel , Gligor Dan , Martínez Úrsula , Fernández Jose , Tinao Ignacio
Published: July 2022

This manuscript summarizes the educational and scientific outcome of the Research-based learning activities performed in the bachelor’s, master’s, and doctorate programmes in aerospace engineering at the Technical University of Madrid. The activities are related to the line of research in Phase Change Materials in microgravity developed at the Spanish User Support and Operations Centre. The principal scientific results obtained during these years are outlined, drawing particular attention to those related to the “Thermocapillary Effects in Phase Change Materials in Microgravity” experiment and the “Effect of Marangoni convection on heat transfer in Phase Change Materials” project. The outcomes of this research are discussed from an educational perspective. Since 2016, we observe an increased interest from students to participate in research activities, which has had direct positive impact on the production of scientific results
Bem-estar social em economia: Utilitarismo Benthamita ou Igualitarismo Seniano?
Authors: Moraes Mayara da Mata , Marin Solange Regina
Published: July 2022

O objetivo deste artigo é fazer uma revisão de literatura a respeito de como o utilitarismo clássico de Jeremy Bentham e o igualitarismo de Amartya Sen compreendem o bem-estar.  Bentham, com seu princípio da utilidade, foi um dos grandes influenciadores do que hoje se constitui como a economia do bem-estar predominante que entende bem-estar como função de utilidade e concebe o indivíduo com uma razão calculadora inata. Amartya Sen, crítico desse pensamento e seguindo os ensinamentos de Smith sobre motivação humana, apresenta a abordagem das capacitações com o objetivo de discutir bem-estar e de enfrentar problemas como desigualdades, garantia de direitos e pobrezas.
Analytical study on effect of central opening of masonry infill to the lateral strength of RC Frame structure
Authors: Medriosa Hamdeni , Maidiawati M , Tanjung Jafril , Zaidir Z
Published: July 2022

In order to get accuration analytical model for describing the lateral strength of brick masonry with openings, a newly simple method was introduced. Comparison of reinforced concrete frame structures with openings and the experimental results of brick masonry with openings (holes) of 25% and 40% was used in this analytical model. In the high-risk seismic areas many reinforced concrete buildings with infill frame with openings. Where the presence of openings will reduce the strength of the wall. In addition, the influence of the area and location openings in the walls are strongly needed to obtain a more realistic method for designing reinforced concrete structures. The brick mansory was assumed as the non-structural component. However, based on the observations after the earthquake, the presence of brick masonry has a significant contribution to the seismic capacity of reinforced concrete structures. The diagonal strut method was used, where the elastic and plastic behavior of the fill-portal by considering the limited ductility of the infill frame material. The comparison of the new analytical model and the experimental brick masonry with opening 25% and brick masonry with opening 40% shows a good agreement. Finally, it can be said that the new analytical model can be used.
An analysis of factors influencing the development of self-employment digitalization based on fuzzy logic
Authors: Plotnikov Andrei , Vorobets Taras , Urasova Anna
Published: July 2022

Self-employment in the Russian Federation is a special tax regime; tax on personal income is a simplified form of entrepreneurship. The self-employed are often associated with freelancers. The exponential growth of information increases uncertainty, and the development of digitalization levels out uncertainty. This work analyses the factors influencing the digitalization development of self-employment as an integral indicator that can affect the sustainability of self-employment. The main method used is a topological method based on the polymerase chain reaction method, as well as the model based on fuzzy sets theory - Mamdani fuzzy inference algorithms. The data for the study were collected through a survey posted on Google Forms. The respondents were experts in the self-employment sector. Eight people participated in the survey (4 - self-employed; 4 - university professors). The self-employed comprised the following areas: developer - 1; service worker - 1; online marketer - 1; musician, event host - 1. Further calculations were performed in Mathlab. According to the study results, the level of factors in the development of self-employed digitalization is 0.502, which corresponds to the third interval of the five-level classifier and has growth potential.
High Performance Computing (HPC) Security:
Authors: Guo Yang , Chandramouli Ramaswamy , Wofford Lowell , Gregg Rickey , Key Gary , Clark Antwan , Hinton Catherine , Prout Andrew , Reuther Albert , Adamson Ryan , Warren Aron , Bangalore Purushotham , Deumens Erik , Farkas Csilla
Published: July 2022

Security is an essential component of high-performance computing (HPC). HPC systems often differ based on the evolution of their system designs, the applications they run, and the missions they support. An HPC system may also have its own unique security requirements, follow different security guidance, and require tailored security solutions. Their complexity and uniqueness impede the sharing of security solutions and knowledge. This NIST Special Publication aims to standardize and facilitate the information and knowledge-sharing of HPC security using an HPC system reference model and key components as the basics of an HPC system lexicon. This publication also analyzes HPC threats, considers current HPC security postures and challenges, and makes best-practice recommendations.
Trabajo en cooperativas y acción colectiva. La subjetividad política como herramienta analítica
Authors: Veas Rocío
Published: July 2022

Las cooperativas de trabajo no solo han cumplido un importante rol paliativo ante los efectos adversos del sistema capitalista, sino que también han sido concebidas desde sus inicios como espacios efectivos o potenciales de transformación social. Con el objetivo de abordar este segundo rol disruptivo o transformador, el artículo propone caracterizar los procesos de subjetivación política que tienen lugar en el marco del trabajo colectivo, mediante los conceptos de subalternidad, antagonismo y autonomía. La estrategia metodológica se basa en un estudio en profundidad de cooperativas uruguayas: dos industriales, de integración obrera, y otras dos de servicios profesionales. La técnica principal es la entrevista en profundidad, complementada con la observación participante y el análisis de fuentes secundarias. El análisis del nivel individual implicó la construcción de una tipología que considera el sentido quedan al trabajo en cooperativas sus integrantes, y distingue entre trabajadores militantes, por necesidad, indiferentes y los perfiles híbridos. Los resultados del nivel colectivo muestran que la consolidación de cooperativas antagónicas, con un mayor impacto social, se relaciona con la presencia de objetivos ideológicos, los modelos participativos y una amplia consideración del plano reproductivo y de necesidades personales. Por su parte, la conformación de cooperativas subalternas ocurre cuando existen fuertes restricciones económicas y cuando se reproducen lógicas individualistas, con falta de participación e involucramiento. Se concluye sobre distintas nociones asociadas a la autonomía (como autodeterminación, libertad y desprotección) y se analiza la extensión de los resultados a otros contextos.
Cumplimiento normativo sobre información sostenible de las empresas españolas y sus efectos en los avances de la Agenda 2030
Authors: Gutiérrez Ponce Herenia , Chamizo González Julián , Puentes Gomez Johanna
Published: July 2022

La denominada información ESG (Environmental Social Governance) y concretada en Objetivos de Desarrollo Sostenible (ODS) es cada vez más significativa en las economías de todo el mundo y contribuye a la transparencia de las organizaciones. En este sentido, el ordenamiento europeo y español establece que las empresas incluyan en sus informes anuales información no financiera sobre medioambiente, aspectos sociales y de gobernanza. Esta investigación tiene como objetivo analizar el cumplimiento normativo o compliance de las empresas españolas en materia medioambiental, social y de gobernanza desde una perspectiva multidisciplinar: la jurídica y la económica. Se ha realizado una investigación cualitativa mediante un estudio exploratorio, descriptivo y analítico de la relación entre las malas prácticas empresariales que configuran delitos penales durante el periodo de diciembre de 2015 y diciembre de 2019 y su repercusión en los ODS. Los resultados demuestran la importancia de implementar modelos de prevención y gestión de riesgos en los informes, así como procedimientos de auditoría de cumplimiento de la legislación en materia Environmental Social Governance (ESG). Además, se evidencia el impacto negativo de los delitos empresariales en un conjunto de ODS y metas que afectan a las Cinco Áreas Críticas de la Agenda de Desarrollo (las cinco P`s) analizando las sentencias dictadas por el Tribunal Supremo español (TS) que son una fuente valiosa de información cuantitativa y cualitativa que debería incluirse en el “Estado no financiero” y en Global Reporting de las empresas.
Desarrollo cooperativo a partir del impulso sindical. El caso de las Cooperativas de Artistas y Oficios Conexos en Uruguay
Authors: Romero Melina , Torrelli Milton
Published: July 2022

El cooperativismo uruguayo se caracteriza por su fuerte vinculación con gremios y sindicatos, siendo la figura cooperativa frecuentemente utilizada como herramienta para abordar las reivindicaciones sindicales. Es el caso de las Cooperativas de Artistas y Oficios Conexos (CAOC), una nueva figura jurídica en el país, creada a partir de negociaciones entre los sindicatos de las artes escénicas y el Estado, que busca incluir en la seguridad social a un sector informal y tradicionalmente desprotegido. Este trabajo analiza, a partir de un estudio de caso de abordaje cualitativo, la singularidad de la relación entre estos sindicatos y las dos primeras cooperativas de artistas establecidas (Valorarte y Coopaudem). El objetivo es comprender el funcionamiento de estas organizaciones que, tal como se observa en el abordaje conjunto ante la crisis COVID-19, configuran un claro ejemplo de la posibilidad de generar alianzas estratégicas entre sindicalismo y cooperativismo. El rol protagónico de los sindicatos en el proceso de conformación de esta clase de cooperativas, así como en la fundación de las dos mencionadas CAOC, confirma la clara vigencia de estas cooperativas como herramienta sindical. Asimismo, se constata que esta relación cuasi simbiótica presenta fortalezas en lo operativo y en la consecución de los fines de cada organización, constituyendo una modalidad novedosa e innovadora, pero también tensiona los principios de libre membresía y autonomía cooperativa. Finalmente, se valora que profundiza debilidades en la inserción y vínculo con el resto del sector cooperativo, con quien mantienen un escaso contacto desde su génesis.
Mutational robustness changes during long-term adaptation in laboratory budding yeast populations
Authors: Johnson Milo S , Desai Michael M
Published: July 2022

As an adapting population traverses the fitness landscape, its local neighborhood (i.e., the collection of fitness effects of single-step mutations) can change shape because of interactions with mutations acquired during evolution. These changes to the distribution of fitness effects can affect both the rate of adaptation and the accumulation of deleterious mutations. However, while numerous models of fitness landscapes have been proposed in the literature, empirical data on how this distribution changes during evolution remains limited. In this study, we directly measure how the fitness landscape neighborhood changes during laboratory adaptation. Using a barcode-based mutagenesis system, we measure the fitness effects of 91 specific gene disruption mutations in genetic backgrounds spanning 8000–10,000 generations of evolution in two constant environments. We find that the mean of the distribution of fitness effects decreases in one environment, indicating a reduction in mutational robustness, but does not change in the other. We show that these distribution-level patterns result from differences in the relative frequency of certain patterns of epistasis at the level of individual mutations, including fitness-correlated and idiosyncratic epistasis.
Population-based sequencing of Mycobacterium tuberculosis reveals how current population dynamics are shaped by past epidemics
Authors: Cancino-Muñoz Irving , López Mariana G , Torres-Puente Manuela , Villamayor Luis M , Borrás Rafael , Borrás-Máñez María , Bosque Montserrat , Camarena Juan J , Colijn Caroline , Colomer-Roig Ester , Colomina Javier , Escribano Isabel , Esparcia-Rodríguez Oscar , García-García Francisco , Gil-Brusola Ana , Gimeno Concepción , Gimeno-Gascón Adelina , Gomila-Sard Bárbara , Gónzales-Granda Damiana , Gonzalo-Jiménez Nieves , Guna-Serrano María Remedios , López-Hontangas José Luis , Martín-González Coral , Moreno-Muñoz Rosario , Navarro David , Navarro María , Orta Nieves , Pérez Elvira , Prat Josep , Rodríguez Juan Carlos , Ruiz-García Ma Montserrat , Vanaclocha Hermelinda ,   Valencia Region Tuberculosis Working Group, Comas Iñaki
Published: July 2022

Transmission is a driver of tuberculosis (TB) epidemics in high-burden regions, with assumed negligible impact in low-burden areas. However, we still lack a full characterization of transmission dynamics in settings with similar and different burdens. Genomic epidemiology can greatly help to quantify transmission, but the lack of whole genome sequencing population-based studies has hampered its application. Here, we generate a population-based dataset from Valencia region and compare it with available datasets from different TB-burden settings to reveal transmission dynamics heterogeneity and its public health implications. We sequenced the whole genome of 785 Mycobacterium tuberculosis strains and linked genomes to patient epidemiological data. We use a pairwise distance clustering approach and phylodynamic methods to characterize transmission events over the last 150 years, in different TB-burden regions. Our results underscore significant differences in transmission between low-burden TB settings, i.e., clustering in Valencia region is higher (47.4%) than in Oxfordshire (27%), and similar to a high-burden area as Malawi (49.8%). By modeling times of the transmission links, we observed that settings with high transmission rate are associated with decades of uninterrupted transmission, irrespective of burden. Together, our results reveal that burden and transmission are not necessarily linked due to the role of past epidemics in the ongoing TB incidence, and highlight the need for in-depth characterization of transmission dynamics and specifically tailored TB control strategies.
Senescent preosteoclast secretome promotes metabolic syndrome associated osteoarthritis through cyclooxygenase 2
Authors: Su Weiping , Liu Guanqiao , Mohajer Bahram , Wang Jiekang , Shen Alena , Zhang Weixin , Liu Bin , Guermazi Ali , Gao Peisong , Cao Xu , Demehri Shadpour , Wan Mei
Published: July 2022

Background:

Metabolic syndrome–associated osteoarthritis (MetS-OA) is a distinct osteoarthritis phenotype defined by the coexistence of MetS or its individual components. Despite the high prevalence of MetS-OA, its pathogenic mechanisms are unclear. The aim of this study was to determine the role of cellular senescence in the development of MetS-OA.

Methods:

Analysis of the human osteoarthritis initiative (OAI) dataset was conducted to investigate the MRI subchondral bone features of MetS-human OA participants. Joint phenotype and senescent cells were evaluated in two MetS-OA mouse models: high-fat diet (HFD)-challenged mice and STR/Ort mice. In addition, the molecular mechanisms by which preosteoclasts become senescent as well as how the senescent preosteoclasts impair subchondral bone microenvironment were characterized using in vitro preosteoclast culture system.

Results:

Humans and mice with MetS are more likely to develop osteoarthritis-related subchondral bone alterations than those without MetS. MetS-OA mice exhibited a rapid increase in joint subchondral bone plate and trabecular thickness before articular cartilage degeneration. Subchondral preosteoclasts undergo senescence at the pre- or early-osteoarthritis stage and acquire a unique secretome to stimulate osteoblast differentiation and inhibit osteoclast differentiation. Antagonizing preosteoclast senescence markedly mitigates pathological subchondral alterations and osteoarthritis progression in MetS-OA mice. At the molecular level, preosteoclast secretome activates COX2-PGE2, resulting in stimulated differentiation of osteoblast progenitors for subchondral bone formation. Administration of a selective COX2 inhibitor attenuated subchondral bone alteration and osteoarthritis progression in MetS-OA mice. Longitudinal analyses of the human Osteoarthritis Initiative (OAI) cohort dataset also revealed that COX2 inhibitor use, relative to non-selective nonsteroidal antiinflammatory drug use, is associated with less progression of osteoarthritis and subchondral bone marrow lesion worsening in participants with MetS-OA.

Conclusions:

Our findings suggest a central role of a senescent preosteoclast secretome-COX2/PGE2 axis in the pathogenesis of MetS-OA, in which selective COX2 inhibitors may have disease-modifying potential.

Funding:

This work was supported by the National Institutes of Health grant R01AG068226 and R01AG072090 to MW, R01AR079620 to SD, and P01AG066603 to XC.
Global analysis of cytosine and adenine DNA modifications across the tree of life
Authors: Varma Sreejith Jayasree , Calvani Enrica , Grüning Nana-Maria , Messner Christoph B , Grayson Nicholas , Capuano Floriana , Mülleder Michael , Ralser Markus
Published: July 2022

Interpreting the function and metabolism of enzymatic DNA modifications requires both position-specific and global quantities. Sequencing-based techniques that deliver the former have become broadly accessible, but analytical methods for the global quantification of DNA modifications have thus far been applied mostly to individual problems. We established a mass spectrometric method for the sensitive and accurate quantification of multiple enzymatic DNA modifications. Then, we isolated DNA from 124 archean, bacterial, fungal, plant, and mammalian species, and several tissues and created a resource of global DNA modification quantities. Our dataset provides insights into the general nature of enzymatic DNA modifications, reveals unique biological cases, and provides complementary quantitative information to normalize and assess the accuracy of sequencing-based detection of DNA modifications. We report that only three of the studied DNA modifications, methylcytosine (5mdC), methyladenine (N6mdA) and hydroxymethylcytosine (5hmdC), were detected above a picomolar detection limit across species, and dominated in higher eukaryotes (5mdC), in bacteria (N6mdA), or the vertebrate central nervous systems (5hmdC). All three modifications were detected simultaneously in only one of the tested species, Raphanus sativus. In contrast, these modifications were either absent or detected only at trace quantities, across all yeasts and insect genomes studied. Further, we reveal interesting biological cases. For instance, in Allium cepa, Helianthus annuus, or Andropogon gerardi, more than 35% of cytosines were methylated. Additionally, next to the mammlian CNS, 5hmdC was also detected in plants like Lepidium sativum and was found on 8% of cytosines in the Garra barreimiae brain samples. Thus, identifying unexpected levels of DNA modifications in several wild species, our resource underscores the need to address biological diversity for studying DNA modifications.
A machine learning-based approach for sentiment analysis on distance learning from Arabic Tweets
Authors: Almalki Jameel
Published: July 2022

Social media platforms such as Twitter, YouTube, Instagram and Facebook are leading sources of large datasets nowadays. Twitter’s data is one of the most reliable due to its privacy policy. Tweets have been used for sentiment analysis and to identify meaningful information within the dataset. Our study focused on the distance learning domain in Saudi Arabia by analyzing Arabic tweets about distance learning. This work proposes a model for analyzing people’s feedback using a Twitter dataset in the distance learning domain. The proposed model is based on the Apache Spark product to manage the large dataset. The proposed model uses the Twitter API to get the tweets as raw data. These tweets were stored in the Apache Spark server. A regex-based technique for preprocessing removed retweets, links, hashtags, English words and numbers, usernames, and emojis from the dataset. After that, a Logistic-based Regression model was trained on the pre-processed data. This Logistic Regression model, from the field of machine learning, was used to predict the sentiment inside the tweets. Finally, a Flask application was built for sentiment analysis of the Arabic tweets. The proposed model gives better results when compared to various applied techniques. The proposed model is evaluated on test data to calculate Accuracy, F1 Score, Precision, and Recall, obtaining scores of 91%, 90%, 90%, and 89%, respectively.
The Christology behind The Black Messiah
Authors: Petersen Carsten Elmelund
Published: July 2022

Abstract Allan Boesak developed his ethics of the Black Messiah in the 1970s while he wrote his dissertation in Kampen, The Netherlands. These ethics said no to slavery, colonialism, apartheid, racism, and poverty as a consequence of oppression. Behind these ethics lies the Christological problem. Jesus Christ is truly God and truly human being, which is the universal Christian creed. What is the relationship between the universal confession to Jesus Christ as true God and true human being and the contextual confession to the Black Messiah? The Black Messiah is black for the black people for identification. Is the true humanity universal and the color contextual? The article gives a possible solution. Keywords: Allan Boesak, Black Theology, Black Ethics, Black Messiah, Black Christ, Christology
Cardiovascular Risk among Healthcare Workers in DCH and DCHC Hospitals during COVID-19 Duty: Correlation of Stress Score with Blood Pressure and Lipid Profile
Authors: Hundekari Jagdish , Wasnik Sanjay , Mittal Rahul , Kot Lokendra
Published: July 2022

Introduction: Healthcare workers (HCW’s) are at the frontline of the Coronavirus Disease-2019 (COVID-19) pandemic, participating directly in the diagnosis and treatment of Coronavirus patients for the past two years. This puts them at a larger risk of causing long-term stress, mental anguish, and other negative psychological impacts. Aim: To evaluate stress score, serum lipid profile and blood pressure in a Dedicated COVID Hospital (DCH) and Dedicated COVID Health centre (DCHC) among HCWs, and to correlate the perception of psychological stress with serum lipid profile. Materials and Methods: This was a hospital-based crosssectional study conducted from the month of March 2021 to August 2021. Seventy-five HCWs (35 men and 40 women) from DCH and DCHC were included in this study. In these participants, socio-demographic and perceived stress, serum lipid profile was measured. The studied population was divided into two groups: Group A (HCWs in direct contact with COVID-19 patients) and Group B (HCWs not in direct contacts with patients). Stress scores, serum lipid levels, systolic and diastolic Blood Pressure (SBP and DBP) of all the participants were measured and compared with that of controls, using Student’s t-test. Stress scores of HCWs in direct contact with patients were correlated with SBP and DBP and serum lipid profile by using Pearson correlation coefficient (r). Results: Stress levels were significantly higher in Group A (p>0.05), but serum lipid levels were not significant. Stress levels of Group A were found to correlate strongly with blood Total Cholesterol (TC), (p<0.001) serum Triglyceride (TG), (p<0.01) High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), LDL/HDL, and SBP and DBP (p<0.001). Conclusion: Stress scores were elevated in HCWs in direct contact with patients (Group A) and these strongly correlate with serum lipid levels and BP. The health authorities are responsible for implementation of strategies to manage this psychological stress.
Estimation of the Resource Use Efficiency and Constraints Faced by the Farmers in Sugarcane Cultivation in Balrampur District of Uttar Pradesh
Authors: Tripathi Devendra Mani , Maurya Mukesh Kumar , Kumari Suman , Karchuli Amit Singh
Published: July 2022

To study the resource use efficiency and constraints faced by the farmers in Balrampur district of Uttar Pradesh was conducted in agriculture year 2020-21. Multistage sampling technique was used. The study pertains and data gathered was analyzed and it was found that the return to scale in marginal farm was 0.93, in small size farm it was about 0.92 and in medium size farm the return to scale was found to be 0.96. The major constraints faced by the farmers in production of Sugarcane are High cost of Input, High Interest on Loans, High Labor Cost, High Incidence of Disease, Lack of Irrigation water supply, Inadequate Credit, Delay in Sanction of crop loan, Uncertain Weather, Lack of knowledge and important Technology and Poor Soil Fertility and the constraint faced by the farmers in Marketing of Sugarcane are Delay in Cash Payment, High Commission Charges, Malpractices in weighing, Price Fluctuation, High cost of transportation, Lack of storage facility, Market is far from production, Lack of information about government schemes and subsidies, Illegal deduction and Lack of skilled labor.