bluuebunny/crossref_metadata_2025 huggingface dataset:
La búsqueda y el fracaso en la inteligibilidad como parte de la construcción de la identidad dramática
Authors: Rivero-Obra Mercedes
Published: May 2024

The Theory of Narrative Identity attempts to answer multiple concerns about the construction of self-concept. It suggests that the subject gives sense to their experiences by assimilating them as a set of narratives that explain their existence. This approach provides them with a foundation that makes it easy for them to gain self-understanding and plan their actions. However, the Theory of Narrative Identity is unable to face important difficulties related to intelligibility and social interaction. This work presents an alternative proposal thanks to the Theory of Dramatic Identity, which focuses its study on the action of the individual itself.

La Teoría narrativa de la identidad trata de dar respuesta a múltiples inquietudes sobre construcción del autoconcepto. Esta sugiere que el sujeto da sentido a su experiencia al asimilarla como un conjunto de narraciones que explican su existencia. Esto le proporciona una base que le facilita adquirir autocomprensión y planificar sus acciones. Sin embargo, la Teoría Narrativa de la identidad es incapaz de enfrentar importantes dificultades relacionadas con la inteligibilidad y la interacción social. Este trabajo presenta una propuesta alternativa a través de la Teoría dramática de la identidad, que centra su estudio en la agencia del sujeto.
“Nos falta esta última fuerza. Nos falta un pueblo”. Notas sobre el pensamiento y el pueblo que falta
Authors: Ramírez Vargas Carlos
Published: May 2024

There is a phrase by Paul Klee that insists and repeats itself in Deleuze's writing: "We are missing this last force. We are missing a people". However, the contemporary world is defined precisely by the fullness and the becoming population of peoples. This is why the concept of people constitutes an amphibology that is revealed in Deleuze's work as an appearance between people and thought. In this sense, the relationship between both concepts shows a set of aesthetic, political, and ontological consequences that these notes attempt to address in Deleuze's thought and beyond.

Hay una frase de Paul Klee que insiste y se repite en la mano de Deleuze: “Nos falta esta última fuerza. Nos falta un pueblo”. Sin embargo, el mundo contemporáneo se define justamente por el lleno y el devenir población de los pueblos. Es por esto que el concepto de pueblo constituye una anfibología que se revela en el trabajo de Deleuze como una comparecencia entre pueblo y pensamiento. En este sentido, la relación entre ambas categorías muestran un conjunto de consecuencias estéticas, políticas y ontológicas que estas notan intentan abordar en el pensamiento de Deleuze y más allá de éste.
La violencia de la voluntad general. Sobre la crítica a Rousseau en la Fenomenología del espíritu de Hegel
Authors: De Nicola Juan Pablo
Published: May 2024

El artículo analiza el tratamiento hegeliano del concepto de voluntad general de Rousseau en la Fenomenología del espíritu. Se teje una trama conceptual que enfatiza en: (i) la necesariedad del concepto de voluntad general de Rousseau en el entramado conceptual hegeliano; (ii) las implicancias de este concepto en la estructura política y social, en términos de una ausencia de instituciones de representación política en una sociedad ética; (iii) las consecuencias violentas y nihilistas de la extrapolación práctica de la voluntad general como axioma teórico.
PENGARUH DISIPLIN KERJA DAN MOTIVASI KERJA TERHADAP KINERJA PEGAWAI KANTOR CAMAT MEDAN TIMUR
Authors: Pasaribu Nexsi , Sitanggang Cindy , Tambunan Toman Sony
Published: May 2024

Penelitian ini mengangkat permasalahan: kinerja pegawai mengalami penurunan; disiplin kerja masih tergolong rendah: motivasi kerja kurang.Tujuan penelitian ini unutuk membangun model dengan menanalisis hubungan pengaruh antara variabel Disipin Kerja,Motivasi Kerja,Kinerja Pegawai. Jumlah sampel dalam penelitian ini adalah 18 pegawai. Berdasarkan latar belakang masalah,dirumuskan 3 hipotesis. Teknik pengumpulan data adalah menggunakan Kuisioner.Jenis penelitian yang digunakan adalah penelitian Kuantitatif. Data yang terkumpul selanjutnya dianalisis dengan menggunakan Uji Validitas, Uji Reabilitas, Analisis Regresi Linier Berganda, Uji Hipotesis dan Koefisien Determinasi, dengan bantuan program SPSS Version 22 For Windows. Hasil penelitian ini adalah: Pertama,Disiplin Kerja berpengaruh positif dan signifikan terhadap Kinerja Pegawai. Kedua,Motivasi Kerja berpengaruh positif dan signifikan terhadap Kinerja Pegawai. Ketiga, Disiplin Kerja dan Motivasi Kerja berpengaruh positif dan signifikan secara parsial terhadap Kinerja Pegawai
PENGARUH STRATEGI PEMASARAN ONLINE TERHADAP KEPUTUSAN PEMBELIAN PADA PLATFORM SHOPEE
Authors: Yosefin Theresia Manurung  , Ayu Juliani Teresia Daeli  , Toman Sony Tambunan
Published: May 2024

Penelitian ini mengangkat permasalahan  strategi pemasaran  masih tergolong rendah, dan konsumen belum sepenuhnya merasa puas dalam berbelanja online sehingga bisa mempengaruhi keputusan pembelian. Tujuan penelitian ini adalah untuk mengetahui pengaruh strategi pemasaran terhadap keputusan pembelian pada platform Shopee. Berdasarkan latar belakang masalah, di rumuskan 2 hipotesis, yaitu dengan variabel independent strategi pemasaran (X) dan variabel dependent keputusan pembelian (Y). Jumlah sampel dalam penelitian ini adalah 56 konsumen. Jenis penelitian ini adalah kuantitatif dengan variabel independent strategi pemasaran (X) dan variabel dependent keputusan pembelian (Y). Dalam menganalisis data menggunakan regresi sederhana, uji hipotesis dan koefisien determinasi dengan bantuan program SPSS version 26 For Windows. Berdasarkan hasil uji parsial (uji t) dapat disimpulkan bahwa strategi pemasaran mempunyai pengaruh positif dan signifikan terhadap keputusan pembelian, dimana positif ditunjukkan dengan nilai 74,462 dan signifikan ditunjukkan dengan 0,000 < 0,05. Hasil penelitian ini adalah variabel strategi pemasaran berpengaruh secara positif dan signifikan terhadap keputusan pembelian.
PENGARUH PROMOSI DAN GAYA HIDUP TERHADAP KEPUTUSAN PEMBELIAN GO-FOOD DI KOTA MEDAN
Authors: AdenovlinBonivasya  , Toman Sony Tambunan
Published: May 2024

Go-Food merupakan fitur yang menyediakan layanan belanja makanan dan minuman pesan antar kepada pelanggan. Layanan ini sangat cocok bagi konsumen yang ingin menikmati berbagai jenis makanan cepat saji, namun tidak memiliki motor atau waktu serta tidak mengetahui akses jalan. Konsumen lebih mudah mengambil keputusan pembelian makanan dan minuman melalui Go - Food karena memerlukan sedikit usaha dan tidak terlalu rumit dalam bertransaksi. Penelitian ini bertujuan untuk mengetahui pengaruh: (1) promosi terhadap keputusan pembelian, (2) gaya hidup terhadap keputusan pembelian, dan (3) promosi dan gaya hidup terhadap keputusan pembelian. Penentuan sampel dilakukan dengan cara insidental sampling sehingga diperoleh sebanyak 52 orang sampel. Dalam menganalisis data menggunakan regresi berganda, uji hipotesis yakni uji parsial dan uji anova serta koefisien determinasi dengan bantuan program SPSS. Berdasarkan uji parsial dapat disimpulkan bahwa promosi yang dilakukan Go-Food mempunyai pengaruh terhadap keputusan pembelian dan gaya hidup juga memilki pengaruh terhadap keputusan pembelian masyarakat.  Hasil uji Anova menunjukkan bahwa secara simultan promosi dan gaya hidup memiliki pengaruh terhadap keputusan pembelian.
PENGARUH HUBUNGAN KERJA DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN PT. TOBA PULP LESTARI MEDAN
Authors: Lonisa Melfrinda Br. Ginting  , Eka Sonia Br.Tarigan  , Toman Sony Tambunan
Published: May 2024

Tujuan penelitian ini adalah untuk mengetahui pengaruh hubungan kerja dan motivasi kerja terhadap kinerja karyawan pada PT. Toba Pulp Lestari. Jenis penelitian ini adalah Kuantitatif dengan dua variabel independen yang terdiri dari hubungan kerja (X1), motivasi kerja (X2), dan variabel dependen kinerja karyawan PT. Toba Pulp Lestari (Y). Sampel yang diambil menggunakan metode slovin dan populasi sebanyak 35 karyawan. Data yang terkumpul selanjutnya dianalisis dengan menggunakan analisis regresi linear berganda, uji hipotesis dan koefisien determinasi dengan bantuan program SPSS Version 25 For Windows. Hasil penelitian dapat diketahui bahwa hubungan kerja, motivasi kerja berpengaruh signifikan terhadap kinerja karyawan PT. Toba Pulp Lestari. Hal ini diperkuat dengan signifikansi pengaruh masing-masing dan seluruh variabel < 0,05 sehingga hipotesis dapat diterima. Dari hasil penelitian menunjukkan bahwa hubungan kerja dan motivasi kerja terbukti mempengaruhi kinerja karyawan pada PT. Toba Pulp Lestari. Maka pemimpin harus bisa memberikan motivasi kepada karyawannya dan mencontohkan hubungan kerja yang baik.
PENGARUH BEBAN BERLEBIH TERHADAP UMUR RENCANA PERKERASAN JALAN (STUDI KASUS JALAN CEMARA MEDAN)
Authors: Hidayat Iman , Putra Nusa Eka
Published: May 2024

Tujuan penelitian ini : (1) memahami pengaruh beban berlebih (overload) pada perkerasan jalan dan (2) menganalisis pengaruh beban berlebih (overload) pada perkerasan jalan menggunakan metode Bina Marga (BM) 2013. Jenis penelitian yang digunakan dalam penelitian ini yaitu penelitian survei dengan jenis data kuantatif. Data yang dikumpulkan berupa data primer diperoleh dari pengamatan secara langsung di jalan Cemara Medan dan data sekunder yang diperoleh dari institusi Pemerintah. Metode analisis data yang digunakan pada penelitian ini mengacu pada Manual Desain Perkerasan Jalan Nomor 02/M/BM/2013 yang dikeluarkan Kementerian Pekerjaan Umum Direktorat Jendral Bina Marga yakni dengan : (1) mencari angka ekivalen kendaraan, (2) menghitung angka ekivalen akibat adanya beban berlebih kendaraan,  dan (3) menghitung nilai CES. Hasil penelitian menunjukkan bahwa : (1) adanya beban berlebih (overload) mengakibatkan perubahan angka ekivalen yang cukup besar karena penambahan beban melebihi beban sumbu standar pada sumbu kendaraan yang menyebabkan penambahan daya rusak yang cukup signifikan. Kerusakan terjadi lebih cepat karena konsentrasi beban tiap roda kendaraan sangat tinggi apalagi dengan adanya beban berlebih, karena pada perencanaan perkerasan jalan masih mengacu kepada desain kendaraan untuk muatan normal. Mekanisme beban kendaraan dalam mempengaruhi perkerasan jalannya tergantung pada luas bidang kontak ban dan bentuk konfigurasi sumbu kendaraan. (2) Pada kondisi tanpa adanya pertambahan lalu lintas, maka umur perkerasan diperkirakan akan berakhir pada tahun ke 10 sejak jalan dibuka sesuai dengan rencana. Namun, dengan adanya kondisi pertambahan lalu lintas 10% maka terjadi pengurangan dengan persentase (-10%) dari umur rencana 10 tahun.
Influence Free Cash Flow and Growth Opportunity against Company Values with leverage as a Variable Intervening
Authors: Agostinho Pinto Soares  , Muchlis Mas'ud  , Alfiana
Published: May 2024

The purpose of this research is to test and analyze the effect free cash flow and growth opportunities to company value with leverage as a variable intervening in textile and garment companies on the IDX in the 2019-2022 period. In this study the approach used by researchers is quantitative research and uses statistical formulas to help analyze the data and facts obtained. This data collection uses secondary data which can be taken from the Textile and Garment Sector companies listed on the IDX in the 2019-2022 period. The research model used ispath analysis. Data processing path analysis using program assistance IBM SPSS Statistics 25. The research results conclude Free Cash Flow not able to affect the value of the company (PBV), Free Cash Flow able to influence Leverage (THE), Growth opportunity (PER) is able to affect the value of the company (PBV), Growth opportunity (PER) is not able to influence leverage (THE), Leverage (DER) is not able to affect the value of the company (PBV), Leverage (DER) is not able to mediate the relationship between free cash flow to firm value (PBV), Leverage (DER) is not able to mediate the relationship between Growth Opportunity (PER) to firm value (PBV).
Implementastion of Internal Inventory Merchandise Control System
Authors: Dita Andhini Setiyowati  , Dwi Anggarani  , Endah Puspitosarie
Published: May 2024

Internal control is a security measure to prevent damage, theft or other irregularities. The formulation of the problem in this research is "How is the implementation of the internal control system for merchandise inventory at PT. Sinarmas Distribution Nusantara Malang Branch.” The purpose of this research is to find out how the internal control system for merchandise inventory at PT. Sinarmas Distribution Nusantara Malang Branch. This type of research is descriptive research. The data analysis method used in this research is qualitative analysis. Results of research into PT's internal inventory control. Sinarmas Distribution Nusantara Malang Branch is in accordance with the five components of internal control according to COSO. This shows that internal control over merchandise inventory at PT. Sinarmas Distribution Nusantara Malang Branch is in the very effective category. In order for internal control over inventory to be more effective, companies should be more committed to existing ethics and carrying out work in accordance with predetermined duties and responsibilities.
Market Retribution Market Potential Analysis in Malang City
Authors: Mulyono  , Survival
Published: May 2024

The factors that determine the success of collecting market levies are the number of traders, the area of ​​kiosks, stalls and open grounds, rates and the collection performance (efficiency and effectiveness of collection) of market levies. Because more and more people are taking advantage of regional government services, regional revenues from levies are also increasing. This can be seen from the economic development of the Malang City area, therefore the presence of traders greatly influences the effectiveness of market levy receipts. The aim of the work on preparing this potential market levy analysis document is to: 1) Examine current market management patterns based on relevant regulations or policies. 2) Identify and study the pattern of determining levies or rents on markets based on market classification in order to measure more optimal levels of income. This type of research is policy research which aims to explore various information related to market service fees in order to provide recommendations for policy making for regional (market) asset management. The analysis technique in this research uses descriptive statistical analysis techniques. The research results show that optimization of sources of Regional Original Income (PAD), including market levies, needs to be carried out to improve the regional financial capacity of Malang City. What can be done immediately is to intensify existing regional income objects or sources, especially through the use of information technology.
Exploring Ungrammatical Patterns in Indonesian Student Thesis Writing: A Comprehensive Analysis
Authors: Susanto Arju , Darwis Muhammad , . Lukman , . Kaharuddin
Published: May 2024

This research discusses the pattern of ungrammatical Indonesian language in student thesis writing. This research aimed 1) to describe the pattern of ungrammatical Indonesian in student thesis writing, and 2) to analyze the pattern of ungrammatical Indonesian in student thesis writing. This research used eclectic theories about morpho-syntax, syntax, and task words. This research used descriptive analysis method. The work steps of this research begin with identifying patterns of ungrammatical Indonesian language in student thesis writing, then analyzing and describing it. The results of this research show that there are several patterns of ungrammatical Indonesian language morphosyntactically, combining the affixes me-...-i and me-...-kan, redupliation, and from a syntactic perspective there are ungrammatical structures of phrases, clauses and complete sentences, there are sentences with no subject, sentences with no predicate, and sentences with no subject and no predicate. The research results in terms of task words showed ungrammaticalities in the application of prepositions and conjunctions.
PENGARUH LITERASI KEUANGAN, PERENCANAAN KEUANGAN DAN GAYA HIDUP TERHADAP PENGELOLAAN KEUANGAN PADA IBU RUMAH TANGGA DI DESA BANGAK
Authors: Anis Setianingsih  , Heny Kurnianingsih
Published: May 2024

This research aims to determine the influence of financial literacy, financial planning and lifestyle on planning the needs of housewives in Bangak Village. The population used in this research was housewives who lived in Bangak Village. Sampling method by
Probability Sampling using Simple Random Sampling technique. Determining the number of respondents at 95 using the Slovin formula. The results of the hypothesis t test in this research show that in particular the financial literacy variable (Xi) has a positive and significant influence on financial management (Y). The financial planning variable (X2) has a negative and insignificant effect on financial management (Y). The lifestyle variable (X3) has a positive and significant effect on financial management (Y). Based on the table from the F test, financial literacy, financial planning and lifestyle simultaneously have a positive and significant effect on financial management among housewives in Bangak Village.
The Impact of Life Skills Training on Distress Tolerance, Psychological Adaptation, and High-Risk Behaviors in Incarcerated Women
Authors: Divanbeigi Roya , Manzari Tavakoli Alireza , Manzari Tavakoli Hamdolah
Published: May 2024

Objective: The study aimed to evaluate the impact of life skills training on distress tolerance, psychological adaptation, and high-risk behaviors among incarcerated women. Methods: This was an applied, experimental study. The study population consisted of incarcerated women in Kerman Central Prison in 2022. Sixty participants exhibiting high-risk behaviors were randomly assigned into an experimental group (30 women) and a control group (30 women). The experimental group received the World Health Organization's (WHO, 1998) ten-session life skills training program, each lasting 90 minutes, while the control group was placed on a waiting list. Both groups were assessed using the Simons and Gaher Distress Tolerance Scale (2005), the Derogatis Psychological Adaptation Scale (1986), and the Rajaee and Shafiei High-Risk Behavior Questionnaire (2011) before and after the intervention. Data were analyzed using multivariate analysis of covariance with SPSS software. Findings: Results indicated that life skills training significantly impacted distress tolerance, psychological adaptation, and high-risk behaviors in incarcerated women (p < .01). Conclusion: Life skills training can be effectively utilized to enhance distress tolerance and psychological adaptation, and to reduce high-risk behaviors.
Novel in silico nano-drug design and delivery systems employing the density functional theory: a review
Authors:   College of Pharmacy, University of Babylon, Hillah, Iraq, Aysa Noor Hadi , Aziz Safa Wahab ,   College of Pharmacy, University of Babylon, Hillah, Iraq, Al-Assaly Rafal ,   College of Pharmacy, University of Babylon, Hillah, Iraq
Published: May 2024

Nanoinformatics is a next-generation method for designing and simulating nanodrug candidates. It involves combining bioinformatics and quantum tools to predict and evaluate drugs. This approach addresses scientific problems in cheminformatics, configuration optimization, drug development, and administration. The integration of bioinformatics and quantum tools is crucial for the understanding of these advancements.
Comparative assessment of the effects of two intrauterine systems for long-term contraception on some haematological, biochemical, and immunological markers
Authors:   Al-Yarmouk Hospital, Al-Karkh Health Office, Baghdad, Iraq, Al-Humadi Farah W. , Waleed Qassim Hiba ,   Al-Karkh Health Office, Ministry of Health, Baghdad, Iraq, Majeed Hameed Ali ,   Baghdad University Hospital, General Directorate of the Medical City, Baghdad, Iraq, Al-Athari Ali Jihad Hamid ,   College of Pharmacy, Al-Mustaqbal University, Hillah, Iraq, Jaber Umran Bushra ,   Department of Gynaecology and Obstetrics, College of Medicine, University of Babylon, Hillah, Iraq, Al-Saigh Rafal J. ,   Department of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Hillah, Iraq
Published: May 2024

An intrauterine system (IUS) is a type of contraception tool that is used in order to control fertility and prevent concep¬tion in women for a long period. The aim of this study was to assess the influence of copper- versus levonorgestrel-releasing IUSs on women’s health. This is a descriptive cross-sectional study of 75 women that were randomly se¬lected (50 women that used a copper-releasing IUS and the remaining 25 that used a levonorgestrel-releasing IUS) amongst those attending out patient’s clinics at Hillah, Iraq, from March to July 2016. All women were between 18 to 46 years of age, and have had an IUS for at least three months. The measurement of serum ceruloplasmin (SCerP), haemoglobin, vitamin D (VD), interleukin-6 (IL-6), and interferon-gamma (IFN-γ) levels was undertaken. Our results revealed that the copper-releasing IUS group has low haemoglobin and VD levels, along with high levels of SCerP and proinflammatory cytokines. One the other hand, the levonorgestrel-releasing IUS group displayed no significant changes on the above markers. We can conclude that the levonorgestrel-releasing IUS is free of any adverse effect when compared to a copper-releasing IUS, at least with regard to the parameters examined by our study.
Beneficial effect of Alhagi maurorum on rats submitted to sulfadimidine-induced kidney injury
Authors:   Department of Biology, College of Science, University of Babylon, Hillah, Iraq, Alkhafaji Nada Mahdi , Alharbi Hussein Jasim ,   Department of Biology, College of Science, University of Babylon, Hillah, Iraq
Published: May 2024

Alhagi maurorum is one of the many plants that have proven effectiveness in folklore medicine and that are still utilized to treat disease or disorders, thanks to their phytochemical compounds and other secondary metabolites. Sulfadimidine, chemical known as 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-sulfonamide, is an antibacterial drug that has side-effects on organs such as the kidney. In this study, the unwanted acute effect of this sulfonamide and of its metabolites was recorded in the form of rat interstitial nephritis and as an increase in creatinine and blood urea nitrogen (BUN) levels. Results showed a significant (P<0.05) decrease in BUN levels in rat groups treated with the ethanolic extract of Alhagi maurorum as a therapy, but there were no significant differences ob¬served in terms of the creatinine levels in these groups. The undertaken histological study revealed an almost normal histological appearance of the kidneys in the two groups of rats that were treated with the plant extract as a therapy after the damage that occurred as a result of the drug injection (interstitial nephritis, infiltration lympho¬cytes, and mild tubular atrophy). Our study suggests a potential benefit from natural plants in the treatment of drug-related adverse effects.
Cytotoxic effects of the Crassula ovata n-hexane fraction on human esophagus cancer KYSE-30 cells
Authors:   Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Babylon, Babylon, Iraq, Al-yassery Hawraa Kareem , Kadhim Enas Jawad ,   Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Baghdad, Baghdad, Iraq
Published: May 2024

The current study shows the cytotoxicity effect of the Crassula ovata n-hexane extract on esophagus can¬cer. C. ovata is a perennial succulent plant belonging to the Crassulaceae family. In Africa, the leaves were used medicinally to cure epilepsy and diarrhoea by boiling them in milk. The hexane fraction, which is obtained through the maceration method, demonstrates the presence of many compounds that have an anticancer effect, which are ob¬tained by gas chromatography - mass spectroscopy. The phytosterol compound was isolated by a preparative thin layer chromato¬graph and was identified by liquid chromatography - mass spectroscopy. The hexane fraction was found to possess a strong anticancer effect against esophagus cancer. The obtained data from the human esophagus cancer KYSE-30 cell-line were analysed by one-way ANOVA, with a significance level of p<0.05.
Ceruloplasmin levels in β-thalassaemia major: therapeutic insights and implications for iron homeostasis
Authors:   College of Pharmacy, University of Babylon, Hillah, Iraq, Al-Hindy Hayder Abdul-Amir , Mousa Mazin J. ,   College of Pharmacy, University of Babylon, Hillah, Iraq, Joudah Muthanna Mohammed ,   Merjan Medical City, Babil Health Directorate, Babylon, Iraq
Published: May 2024

Ceruloplasmin (CP) is an enzyme that has ferroxidase activity and is important in maintaining iron homeostasis and serving as a copper-transporter in the bloodstream. Beta-thalassemia major (BTM), a common hereditary disorder in Iraq, can affect CP activity in patients with iron overload resulting from frequent blood transfusions in order to sustain haemoglobin levels. The current study is a single-center observational research. CP activity was measured in 304 patients (120 females and 184 males). Anthropometric indices were recorded and the iron load status was determined by measuring serum ferritin. Ninety-two healthy individuals were also included as a control group. Our findings re¬vealed no relationship between age, body mass index, or plasma ferritin and CP activity in BTM patients. No significant influence of sex on CP activity was observed. The outcomes provide insight into assumed pathways regulating CP, and add to the growing body of research on CP’s contribution to iron metabolism in BTM patients. To our knowledge, this work is the only study of its kind in Iraq, provides the groundwork for upcoming studies and potential therapeutic lines by generating insightful data on the multifaceted relationships between iron homeostasis, CP, and BTM.
Phytochemical screening and antimicrobial activity of some medicinal plants
Authors:   College of Pharmacy, University of Babylon, Hillah, Iraq, Al-Taei Alaa Hamady Obeid , Saleh Rasha Hadi ,   College of Pharmacy, University of Babylon, Hillah, Iraq, Kadhum Samah Ahmed ,   College of Pharmacy, University of Babylon, Hillah, Iraq, Omran Aseel Mohammad ,   College of Pharmacy, University of Babylon, Hillah, Iraq, Ewadh Ruqaya Munther Jalil ,   College of Pharmacy, University of Babylon, Hillah, Iraq, Owadh Hasanain Hasan ,   Department of Pharmacology and Toxicology, College of Pharmacy, Al-Mustaqbal University, Babylon, Iraq
Published: May 2024

The antimicrobial activity of the aqueous and ethanolic extracts of Myrtus communis, Ammi visnaga, and Equisetum arvense was investigated against Staphylococcus aureus, Escherichia coli, and Candida albicans by using the agar well diffusion method. Serial concentrations (15%, 30%, and 50%) of the extracts of each plant were tested and compared with gentamicin (10 μg) and fluconazole (25 μg). Most of the extract concentrations showed a relatively high antimicrobial activity against all the tested microbes, and the ethanolic extract was more effective than the aque¬ous extract. The activity of plant extracts increased with the increasing extract concentration of Myrtus communis, which appeared to possess a more antimicrobial activity than the other plants assessed; in fact, its ethanolic extract exhibited the highest inhibition zone against S. aureus (32 mm). The ethanolic plant extracts at a concentration of 50% displayed the maximum activity against the herein assessed isolates. Moreover, E. coli showed a higher sensi¬tivity to most extracts, while the lowest effect being noticed on C. albicans.
SOSIALISASI PERILAKU ECO-DRIVING BAGI PENGENDARA SEPEDA MOTOR USIA REMAJA MENUJU PENGHEMATAN ENERGI FOSIL
Authors: Kemas Abdul Fattah , Indriyani
Published: May 2024

Along with the growth of the vehicle population, there is an increase in fuel consumption, where fuel is a source of fossil energy, so at some point, this fossil energy source will run out. For this reason, saving efforts are needed. The growth in the motorized vehicle population is also accompanied by an increase in school-aged or teenage motorcyclists, so efforts to save fuel consumption should also involve school-aged or teenage riders. Eco-driving behaviour needs to be socialized to them. This PKM activity aims to provide knowledge to school-aged or teenage motorbike riders so that there is a willingness to cultivate eco-driving behaviour. Based on the analysis carried out using the paired t-test, the knowledge of socialization participants increased significantly. With this increase in knowledge, it is expected that eco-driving behaviour can become a driving culture, especially for school-aged or teenage drivers.
Socio-Economic Problems of Agricultural Laborers in Punjab (Pakistan)
Authors: Jamshed Farhat , Afzal Afzaal , Arshad Muhammad
Published: May 2024

The development of the agriculture sector is one of the most imperative factors for fulfilling basic human needs, alleviating poverty, boosting shared prosperity, and becoming a significant contributor to national development for most developing countries. Over one billion of the world's labour force is engaged directly and indirectly in this sector, one-third of the world's workforce. Unfortunately, the laborers working in the agriculture sector face multidimensional socioeconomic problems such as poor livelihood conditions, meagre employment circumstances, long working hours, fewer rewards, unavailability of basic safety facilities, remuneration and pitiable nutrition, among others. To understand the contributing factors responsible for socioeconomic problems, this study was conducted in three divisions of Punjab province: Gujranwala, Faisalabad, and Dera Ghazi Khan. For this purpose, a multistage simple random sampling procedure was applied to approach the participants. The interview schedule was used as a tool for data collection and validated through pilot testing. The study's findings revealed that the laborers’ employment conditions could have been more conducive while agricultural laborers were receiving lesser wages. The agricultural laborers have to face many health hazards. In contrast, the majority of the laborers were exploited only due to their illiteracy and ignorance about Government policies and laws related to them. Many participants reported chronic socioeconomic problems significantly associated with their working environment, amenities and available facilities.
SOLUSI PENINGKATAN KUALITAS IMPLEMENTASI HOTS PADA PEMBELAJARAN IPA SEKOLAH DASAR
Authors: Hs Atika Maulidina
Published: May 2024

Tujuan dari penelitian ini adalah untuk mengetahui urgensi HOTS dalam pembelajaran IPA SD, permasalahan dalam penerapannya, dan solusi permasalahan tersebut, sehingga tujuan HOTS di abad 21 dapat tercapai. Metode yang digunakan adalah studi kepustakaan dari 15 artikel terkait untuk mendapatkan informasi terkait dengan tujuan yang telah ditetapkan. Hasil yang diperoleh menunjukkan bahwa HOTS sangat penting untuk diterapkan pada pembelajaran IPA SD, namun dalam penerapannya masih terdapat permasalahan antara lain kurangnya kemampuan berpikir tingkat tinggi siswa, penilaian yang tidak sesuai, dan penggunaan bahan ajar yang tidak relevan. Hal-hal yang dapat dilakukan untuk permasalahan dengan menerapkan konsep pendekatan saintifik, mengubah sistem penilaian menjadi sistem penilaian otentik, dan meningkatkan kualitas bahan ajar agar sesuai dengan HOTS dan tujuan pembelajaran yang dirumuskan K13 untuk menghadapi abad 21 ini
Flow Cytometry: A Versatile and Powerful Tool for Drug Discovery and Development
Authors: Aru Basak , Yanikkaya Demirel Gulderen
Published: May 2024

Flow cytometry, a pivotal tool in clinical and research labs since the discovery of cell markers in the mid-1970s, plays a crucial role across all phases of drug discovery. Modern flow cytometers can detect rare cell types relevant to disease pathogenesis, measure numerous parameters simultaneously, thus, offer versatility in drug screening. In drug discovery studies, flow cytometry contributes to the assessment of drug pharmacokinetics, pharmacodynamics and safety in animal models and clinical trials. It can also be used to monitor drug efficacy and identify biomarkers for diagnosis and prognosis.
In essence, flow cytometry is a versatile, instrumental technique that supports drug discovery from target identification through to clinical development, limited only by the creativity of the researcher and the availability of fluorescent labels or specific size/scatter related findings. This review article focuses on the use of flow cytometry in drug discovery and drug development studies, summarizing not only conventional assays such as immunophenotyping, measurement of programmed cell death pathways and cell division to provide insights into drug effects and patient responses, but also novel approaches including mass cytometry, spectral cytometry, and droplet cytometry.
Keywords: Flow cytometry, drug discovery, drug development, mass cytometry, spectral cytometry
An MMPI short form to estimate profile shape and elevation
Authors: Burger Gary K. , Kabacoff Robert I.
Published: May 2024

Skinner, Reed, and Jackson (1976) have developed a system for characterizing the shape of MMPI profiles by relating them to three superordinate types--Neurotic, Psychotic and Sociopathic. Using a psychiatric sample, a short form was developed to estimate the position of MMPI profiles in this three dimensional system. An elevation scale was also constructed. Cross validated means, standard deviations, reliabilties and validities supported the use of the short form with psychiatric samples. Examples of the use of the short form were also discussed.
Herbæ medicæ: una aproximación a la historia de las boticas y los boticarios jesuitas neogranadinos
Authors: Gómez Gutiérrez Alberto
Published: May 2024

Con la fundación de la Compañía de Jesús en el siglo XVI se fortaleció la indagación científica y social. Esta comunidad religiosa se centró en destinos periféricos, viajando a lugares recónditos con su mensaje evangélico y, adicionalmente, con un espíritu característico de curiosidad y sistematización. Evidencia de ello es la extensa cartografía fluvial que produjeron los misioneros en sus viajes lejos de las ciudades principales en donde instauraron sus bases operativas en el Nuevo Reino de Granada. Una de estas bases fue de orden farmacológico, atendiendo a su conocimiento ilustrado y a su capacidad de indagación de nuevos medicamentos en regiones como la Orinoquia. Se presenta en este artículo el contexto de su instalación en los territorios hoy colombianos.
Selección de documentos sobre la Compañía de Jesús en el Archivo General de la Nación
Authors: Rodríguez Souquet Carlos
Published: May 2024

Esta sencilla contribución a la investigación académica sobre la Compañía de Jesús en Venezuela desea simplemente introducir al repositorio que sobre el tema guarda el Archivo General de la Nación. Ahora bien, antes de cruzar la puerta que conduce a los distintos Fondos, hemos querido reflexionar sobre el posible origen de la desconfianza que movió a Carlos III a expulsar a los Jesuitas de sus Reinos y a trabajar con ahínco por su extinción. Ojalá resulte un itinerario interesante.
Orígenes religiosos de la masonería
Authors: Ferrer Benimeli José
Published: May 2024

La masonería especulativa que hoy conocemos nace en Inglaterra a comienzos del siglo XVIII. Pero la masonería operativa, la de los constructores, de la que es continuación la actual, se remonta a varios siglos antes. Aquí se analizan algunos documentos de diferentes países: Reglamentos, estatutos, ordenanzas, constituciones… de esta masonería europea, desde el siglo XIII hasta el XVIII. Se incide, sobre todo, en los aspectos religiosos de esta masonería operativa estrechamente vinculados con la Iglesia católica.
José Gregorio Hernández, científico y creyente: una luz en la oscuridad
Authors: Duplá Francisco Javier
Published: May 2024

Vivimos en la actualidad una transformación en la manera de entender la fe religiosa, que se deriva de la cultura positivista iniciada en el siglo XIX. En Venezuela esa cultura afectó a los intelectuales del país, pero apenas influyó en la cultura religiosa andina, donde nació José Gregorio Hernández. El artículo recorre la vida de José Gregorio desde su infancia en Isnotú, sus estudios de bachillerato y de medicina en Caracas, su envío a París para adquirir los últimos conocimientos en medicina, su trabajo en Caracas como médico y como catedrático con gran reconocimiento social, sus relaciones familiares muy afectivas, su inesperada muerte y la fama de santidad recientemente reconocida oficialmente por la Iglesia.
La luz a veces impide corroborar si estamos enmascarados. Una lectura de El hablador de Mario Vargas Llosa
Authors: Blancofombona Maguy
Published: May 2024

Dos estudiantes de la Universidad de San Marcos, Lima, inscritos en etnología establecen una amistad mientras realizan sus trabajos de campo con los indios machiguengas, habitantes de la Amazonía peruana. Ambos provienen de medios diferentes, físicamente Saúl Zurata es un personaje con una gran mancha en un lado del rostro como si tuviera una máscara natural que lo separa de los demás.
En Florencia, veintinueve años más tarde, el escritor que ha ido de vacaciones para leer a Dante y a Maquiavelo entra en una galería y descubre unas fotos que muestran a los indios machiguengas. Le llama la atención una donde aparece un hablador y los indios a su alrededor escuchándolo. La imagen produce una sensación tan fuerte en el escritor que este decide que el fotografiado es Mascarita, el compañero de estudios, que se había vuelto hablador y posaba con el loro que siempre llevaba sobre su hombro. El viaje a Florencia ha terminado porque el escritor ha regresado mentalmente a su país natal.
¿Es América parte de Occidente o no? Es preciso dejar de lado los intereses ideológicos que han impedido la integración de los países y de las zonas que conforman al continente, apoyándose en el español que es la lengua que ha consolidado la unión como no lo ha hecho ninguna otra zona del mundo, sin que por ello olvidemos las lenguas locales que integran también al ser americano.
Contra las Logias y las Grafías
Authors: Lahoud Daniel Lahoud
Published: May 2024

El presente ensayo es parte de una investigación que se realizó sobre la vida y obra del Padre Antonio José Sucre, conocido con el título que ostentaba en la metropolitana de Caracas, El Arcediano, se trata de un personaje interesante que ofrece una visión distinta al clero venezolano del siglo XIX, muy vinculado al proyecto liberal que se ejecutó entre los gobiernos de Páez, Guzmán Blanco e incluso en la época del Liberalismo Amarillo. Sucre es además de un prelado culto, alguien que no fue sumiso ante el poder, por lo que resalta por la profundidad y la vehemencia de sus escritos, en el presente ensayo se va a desarrollar la polémica que generó la masonería en su tiempo y cómo esta estaba extendida entre los políticos del país, además la documentación facilita entender cómo había un abismo cultural entre los saberes del Arcediano y las debilidades de un clero con fe, pero que no alcanzaba en su conocimiento a Sucre.
¿Esto es la Civilización? La discusión en relación al Código Civil de 1868
Authors: Lahoud Daniel
Published: May 2024

Este ensayo parte del Patronato del siglo XIX y el intento de consumar un Concordato entre la santa sede y la república, y luego el intento de aprobar un Código Civil en 1868, que aunque no se logró sancionar dio pie a una discusión interesante donde participaron el arzobispo Guevara y Lira, y de una manera muy destacada el arcediano Antonio José Sucre. La polémica por el lado civil y político la realizó Julián Viso. Tocarán temas de la vida de las personas y los llamados bienes de manos muertas, que brindarán un marco propicio para que el Arcediano nos dé una lección de los principios de la sociedad desde la óptica de la Iglesia
El licenciado José Grau: asesor, teniente, intendente, catequista. Un colaborador civil en la “Gran Colombia”
Authors: Perrone Luis Daniel
Published: May 2024

El objetivo de este trabajo consiste en describir y analizar las labores políticas realizadas por el Licenciado José Grau, abogado de Cumaná, en colaboración con el Intendente José Francisco Bermúdez en el Departamento Orinoco de la “Gran Colombia” (antigua República de Colombia), con la finalidad de revisar críticamente la visión que se tiene comúnmente de los gobiernos del siglo XIX como productos de la racionalidad y voluntad de un solo sujeto. Para lograr nuestro cometido recurrimos a un método que combina el estudio institucional y decisional de la política con énfasis en las relaciones interpersonales, en las que entran en juego el reconocimiento y la influencia individual. Por último, desplegamos una serie de conclusiones relativas a las nuevas miradas que podrían surgir de la historia política de Venezuela del siglo XIX si se presta mayor atención a las complejidades de las decisiones colectivas dentro del ámbito del poder público
Ilustración Venezolana y Paideia Colonial
Authors: Nava Contreras Mariano
Published: May 2024

El presente texto forma parte del ensayo titulado Criollo y afrancesado. Para una caracterización de laIlustración venezolana (Caracas, 2014), que mereció el Premio Nacional de Ensayo “Estefanía Mosca”. Se haceun bosquejo de las condiciones históricas y socioeconómicas que condicionaron el surgimiento delpensamiento ilustrado en Venezuela durante la segunda mitad del siglo XVIII, y se comentan las primeras obrasescritas en el país en el espíritu de la Ilustración.
Reinaldo Rojas, Cumaná en la formación del estado-nacional venezolano (1515-1811), Caracas, Ediciones Fundación Centro Gumilla, 2021, 111 pp
Authors: Berrizbeitia Aristeguieta Emilio Luis
Published: May 2024

Reseña
MINERAL STATUS OF GREEN PEAS GROWTH BY DROUGHT AND AMINO ACID SPRAYING
Authors: El-Dewiny Camilia Y. , Mansour Hani A. , Saad AbdelGawad , Saad Sherif S. , Abd-Elmabod S. K. , Mostafa Fayza E. , Azab Nahed A. , R.S Makar , S.A Shahin
Published: May 2024

A greenhouse pot experiment was conducted 2023 at the National Research Centre in Dokki, Cairo, Egypt to investigate the impact of proline and glutamic acid on the growth, photosynthetic pigments, and mineral levels of Green Peas plants. The absence of irrigation has a detrimental impact on the growth of Green Peas plants, namely in terms of plant height, number of green leaves and stem, as well as the dry weight of leaves and top. The depressing impact was greater when irrigation was absent during the blossoming stage compared to the filling stage. This statement holds true for the conditions indicated earlier. In general, the utilization of amino acids (namely glutamic and proline) enhanced development characteristics. The application of glutamic acid resulted in greater plant height, leaf count, and dry weight of both stems and tops compared to the effects of proline spraying. The absence of irrigation at any growth stage in the study had no impact on the concentration of Chlorophyll (Ch. A and Ch. A + Ch. B). However, there was a modest effect on the concentrations of carotenoids and total Chlorophyll. Nevertheless, the concentration of (Ch. B) exhibited an increase during the fruiting phase under drought treatment. However, this rise needed to be more substantial to reach a statistically significant level. The ratio of Chlorophyll A to Ch. B increased exclusively during the dry period. The utilization of glutamic acid resulted in the highest levels of Ch.A, Ch.B total chlorophyll concentrations, with just a modest impact on carotenoid levels. In addition, the ratios of carotenoids in Ch. A and Ch. B, as well as the combined ratios of Ch.A and Ch.B exhibited similar reactions.
BARRIERS TO EXPANDED PROGRAM ON IMMUNIZATION (EPI) AS PERCEIVED BY THE POPULATION OF RAVI TOWN LAHORE, PUNJAB, PAKISTAN
Authors: Jameel Waleed , Ilyas Arooj , Aftab Asad A. , Fasih Muhammad , Ahmad Irfan , Awais Dua
Published: May 2024

This study was conducted to examine the barriers to an Expanded program in Immunization (EPI) as perceived by the population of Ravi Town Lahore, Punjab, Pakistan. A total of 386 respondents participated in this study. Participants were chosen using a non-probability sampling method. Data were collected using a validated questionnaire and analysis was done using Statistical Package for Social Sciences (SPSS). Results revealed that each factor is listed along with its minimum and maximum values, mean, standard deviation, and standard error. For instance, "Where to seek treatment when sick" ranges from 1.00 to 4.00, with a mean of 1.6321 and a standard deviation of 0.87053. Other factors, such as "Long distance to HF" and "Lack of Vaccine," also display similar descriptive statistics. Missed outreach sessions by Vaccinator in the area, long waiting times and lack of health facilities were the major barriers on the part of the government side whereas ignorance, lack of awareness and illiteracy were key barriers on the part of consumers. Ensuring regular visits by vaccinators, accompanied by social mobilization efforts to raise awareness about the importance of vaccination and facilitating the registration of children by Lady Health Workers (LHWs) or Social Promoters (SPs), can significantly improve vaccination outcomes.
Von Neumann-Jordan constant, James constant, and Dunkl-Williams constant for small Morrey spaces
Authors: Mu'tazili Aqfil , Gunawan Hendra
Published: May 2024

In this article, we compute Von-Neumann-Jordan constant, James constant, and Dunkl-Williams constant for small Morrey spaces. We find that the three constants are the same as those for the classical Morrey spaces.
Safety of the suburethral sling surgery by transobturator access in patients under 45 years of age
Authors: Reva I. A. , Chernushenko A. S. , Gvozdev M. Y. , Aliev R. I. , Kotelnikova A. A. , Kim V. S.
Published: May 2024

Introduction. Symptoms of stress urinary incontinence develop with age in every third woman. To date, suburethral sling surgery is the «gold standard» treatment for stress urinary incontinence. Sling operation is possible by various approaches, each of them has its own advantages and disadvantages. It is believed that transobturator access is combined with the risks of damage of the obturator vessels, tendons of the adductor muscles of the thigh, ranches of the genital and anterior labial nerves. In connection with the above, most authors do not recommend the transobturator access for younger patients.

The purpose of the study. To evaluate the efficacy and safety of suburethral sling surgery by transobturator access in patients under 45 years of age suffering from stress and mixed forms of urinary incontinence.

Materials and methods. A single-center, retrospective observational study was conducted. The anamnestic data of the patients, efficacy (according to the examination in the chair, questionnaires ICIQ-SF, IIQ-7) and safety (the presence of erosions of the synthetic prosthesis, dyspareunia and chronic pain by examination, survey and questionnaires VAS, ODI) were evaluated. The analysis of the obtained data was carried out using the Microsoft Excel data array processing program.

Results. After applying the inclusion and exclusion criteria, 61 patients participated in the study. The subjective effectiveness of the operation was 98.3%, the objective effectiveness was 95%. No erosion of the synthetic prosthetic device was observed in any patient. Chronic pain persisting for more than 1 month was noted in 1 patient (1.7%). Complaints of dyspareunia were also noted in only 1 patient (1.7%).

Conclusion. The obtained results indicate the high efficiency and safety of transobturator access, and allow us to conclude that the use of transobturator access as a technique for primary implantation of a suburethral sling in young patients is justified.
Clinical Applications of the Markers of Lithogenic Activity in Kidney Stone Disease
Authors: Alfimov A. E. , Alexeeva D. Yu. , Korolev D. O. , Gorinova D. M. , Enikeev M. E. , Rapoport L. M.
Published: May 2024

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