bluuebunny/crossref_metadata_2025 huggingface dataset:
A study of histomorphological features of fallopian tube and immunohistochemical stains for p53 & ki67 of the fimbrial end of fallopian tube
Authors: Nabina Leishangthem , Mutum Reeta , Laishram Rajesh Singh , Persy Haobijam , Rainy Rajkumari , Hussain Shaik Mahammad Abzal
Published: September 2024

: Fallopian tube is the origin of ovarian cancer especially high grade serous carcinoma. Precursor lesion of ovarian cancers in the fallopian tube now recognized includes p53 signature, secretory cell outgrowth (SCOUT), tubal intraepithelial lesion in transition (TILT) and serous tubal intraepithelial lesion (STIC) through histomorphological features and by using immunohistochemical staining for p53 and ki67. This study emphasizes in detection of precursor lesion in fallopian tube in all resected fallopian tube submitted in the department during the study period. Ability to detect precursor lesion would have profound impact on preventive strategies of ovarian cancer and modalities of management of the disease in the initial stages that ultimately help in reducing the disease burden and increasing overall survival rate.

: To determine the histomorphologiscl features of fallopian tube and to assess the evidence of precursor lesions in fallopian tube epithelium using immunohistochemistry stain p53 and ki67.

: The study was carried out in the department of pathology in collaboration with the department of obstretics and gynecology, regional institute of medical sciences. Study was conducted for two years from September 2018 to August 2020. All the fallopian tubes specimen received during the study period were included in the study except those specimen with damaged, autolyesd, of post radiation therapy and post chemotherapy patients. A total of 120 specimen were collected.

A total of 120 samples were included in the study. Mean age of the participants was 47 years with a minimum age of 24 years and maximum age of 72 years. 56. 7 % of the participants were in post menopausal age group. Out of the 120 cases only 12 cases (10 %) showed p53 signature and one case (0.8%) showed presence of STIC.

: Only one case of STIC was detected in the fallopian tube where the ovary had High grade serous carcinoma. Few cases showed for p53 signature evident by using IHC p53 and ki67 which is more frequent in corresponding ovarian pathology than uterine pathology.
Association of platelet parameters with chronic complications in type 2 diabetes mellitus
Authors: Persy Haobijam , Konjengbam Ratan , Ranabir Salam , Sorokhaibam Babina
Published: September 2024

To determine the association of platelet parameters with chronic complications in patients with type 2 diabetes mellitus.

Platelets play an important role in the integrity of normal homeostasis. Altered platelet morphology and platelet hyperactivity is associated with an increased prothrombotic state. In diabetes mellitus, there is increased platelet activity which eventually play a role in the development of vascular complications which are responsible for its morbidity and mortality.

A hospital based prospective cohort study was performed to study the level of platelet parameters in patients with type 2 diabetes mellitus. Platelet parameters such as platelet count, MPV (Mean Platelet Volume), PDW (Platelet Distribution Width), PCT (plateletcrit) and P-LCR (Platelet-Large Cell Ratio) were assessed using Mind ray BC-5150 Auto Haematology Analyser. The data were entered into SPSS (IBM) version 21 and descriptive statistical methods like mean, standard deviation, percentages, etc. were applied. T-test was applied to find out the association of platelet parameters in patients with type 2 diabetes mellitus at baseline and after 6 months of follow-up.

The age of the study population ranged from (30-60) years. From the total of 110 participants that were followed - up, 98(89.1%) presented with micro vascular complications. On the other hand, 32(29.1%) had at least one macro vascular complication. Platelet parameters – MPV, PDW, PCT and P-LCR were found to be significantly higher in type 2 DM with micro vascular as well as macro vascular complications as compared to those without complications.

Higher values of MPV, PDW, PCT and P-LCR indicates that platelet parameters can be used as better prognostic markers for early detection of diabetic complications and therefore can be used as a simple and cost-effective tool to monitor and predict the risk of micro vascular and macro vascular complications in diabetes.
Plasma cell granuloma middle ear: A rare lesion at a rare site
Authors: Somani Kavita , Singh Pretty , Poduval Sujatha
Published: September 2024

Plasma cell granuloma (PCG) is a rare non-neoplastic lesion, characterised by proliferation of immunoreactive polyclonal plasma cells present in a fibrous background. We present a case of 30 year male who presented with left sided otalgia, tinnitus and otorrhea along with mild conductive hearing loss. On CT scan a diagnosis of CSOM with granulation tissue was made however on histological examination, on microscopy with immunohistochemistry (IHC), it was reported as plasma cell granuloma of the middle ear. Middle ear plasma cell granuloma is a rare entity only few cases are reported in literature so far.

Here, we will discuss clinical presentation, histological diagnosis with IHC and management of this rare entity at an unusual location along with review of literature.
Is there a need for employee protection processes in U.S. organizations today? A comparative study to assess the progress of procedural and distributive justice systems today versus unionization
Authors: Cates Steven , Jackson Jason , O’Hare Carrie
Published: September 2024

This research study was undertaken to complete a comparative study of the seminal work conducted by Anderson and Ruderman on procedural and distributive justice systems versus unionization. This research was conducted in 2023. The main focus of this research effort was to determine if current U.S. organizations were utilizing any form of justice system in protecting employees’ rights and providing processes that would prevent employees from having a desire to join a union for its protections. Parts of the original survey used by Anderson and Ruderman were used in this study to address the research questions and hypotheses posed for this study. A statistical analysis of the data was conducted, and the results indicated employees have a need for protection in their employment relationship. It is suggested that procedural and distributive justice systems be implemented as an alternative to unionization of employees to meet these employee protections.
O uso de inteligência artificial como ferramenta de apoio à linguística aplicada na educação especial inclusiva: revisão bibliográfica
Authors: Milan Davi , Soares Tainara de Sousa , Lucena João Batista , Gomes Antonio José Ferreira , Rodrigues Lucas Ferreira , Oliveira José Walber Vieira de , Schon Gislaine , Frimaio Fabíola de Fátima Andrade
Published: September 2024

O tema deste estudo é a aplicação da inteligência artificial (IA) como ferramenta de apoio à linguística aplicada na educação especial inclusiva. O objetivo principal é investigar como a IA pode ser utilizada para desenvolver soluções tecnológicas que adaptem materiais didáticos, melhorem a comunicação e facilitem a aprendizagem personalizada para estudantes com necessidades educacionais especiais. A metodologia adotada é uma revisão bibliográfica, abrangendo pesquisas científicas e publicações relevantes que discutem a integração de IA em contextos educacionais inclusivos. O levantamento de dados incluiu a análise de estudos de caso e projetos de pesquisa que exemplificam o uso de tecnologias baseadas em IA para atender às diversas necessidades dos alunos. Os resultados obtidos indicam que a IA tem potencial significativo para apoiar o aprendizado de estudantes com deficiências, particularmente na adaptação de materiais didáticos e na superação de barreiras linguísticas e textuais. Tecnologias como assistentes virtuais, softwares de reconhecimento de voz e sistemas de aprendizagem adaptativa demonstraram ser eficazes em melhorar a acessibilidade e a personalização do ensino. Conclui-se que, embora a IA ofereça oportunidades promissoras para a educação especial inclusiva, é necessário um investimento contínuo em pesquisa e desenvolvimento, bem como na formação de professores, para que essas tecnologias possam ser plenamente integradas ao ambiente educacional de forma eficaz e ética.
Innovative Methods for Control of Electric Vehicles
Authors: Vacheva Gergana , Hinov Nikolay , Gilev Bogdan
Published: September 2024

In the current paper is presented an examination of the innovative methods for control of electric vehicles. Principal characteristics of linearization of nonlinear system, model predictive control and neural network are proposed. The main objective of this research is to determine the important advantages and disadvantages of the different approaches for control.
Intellectual Search of Emerging Research Fields Utilizing Large Scientific Publication Arrays: “Public Governance” Field as an Example
Authors: Liliia Matraeva , Julia Sunaeva , Alexey Belyak , Natalia Korolkova , Olga Kaurova
Published: September 2024

In order to predict the development of any scientific field of knowledge, it is necessary to present modern achievements and discoveries, authoritative expert opinions of key scientists of the studied area. However, the Modern “digital Universe” is changing and expanding at such a speed that doubles the amount of data every two years, which has led to the accumulation of huge streams of scientific information that it has become impossible to be covered fully based on traditional scientific search techniques. This article’s outcomes can be used as an intellectual basis by scientists involved in this progressing topic.
Features of the Management Process of Ambidextrous Companies
Authors: Kovtun Vita , Andriushchenko Kateryna , Horbova Natalia , Lavruk Oksana , Yelyzaveta Muzychka Yelyzaveta
Published: September 2024

The main purpose of this paper is devoted to studying economic factors within industrial production and development in the framework of concept Industry 4.0., all in the context features of the management process of ambidextrous companies. The economic factors regarding the development of enterprises under the conditions of digitization are systematized. Such factors as the need to develop a new type of intellectual value chain, production of individual and customized goods with reasonable prices and the use of learning factories have specific meaning in the framework of this problem. The results obtained can be used by business entities while implementing the decoded platform.
Microeconomic Implications of Environmental Tax
Authors: Meta Mehmed , Elfić-Zukorlić Elma , Bećirović Suad , Ćatović Azra
Published: September 2024

The devastation of the environment occurs mainly as a result of intensive economic development. The study of its consequences is a subject of interest of experts from various professional orientations. Economic theorists, ecologists and all those involved in the creation of solutions in the field of environmental policy, product designers and new technological procedures constantly point to the need for alignment of economic development goals and the environmental consequences that economic progress causes. Excluding natural disasters, external diseconomies in production are the most powerful cause of environmental degradation, regardless of whether they occur in the form of hydro, aero or lithium pollution. The aim of this paper is to show how the introduction of pollution taxes affects the behavior of market players, the amount of pollution and the magnitude of social well-being. In most cases, the market mechanism cannot adequately address the problem of negative externalities in production. But, on the other hand, this state, because of limited information on the consequences of environmental damage or for other reasons, through its intervention in the market, can produce an outcome worse than that created by the uncontrolled market.
Implementing the Praxeological Approach to Teaching Practice at Pedagogical University
Authors: Lyashova Nadiia , Pomyrcha Svitlana , Beskorsa Olena , Ishutina Olena , Khvashchevska Olha
Published: September 2024

The article deals with the issue of improving the process of organizing the pre-service teaching as one of the priority conditions for developing future primary school teachers’ professional competence. It is determined that the effective way of solving this problem is to form the future teachers’ successful pedagogical experience while both studying at the university and having teaching practice. The emphasis is on the effectiveness of the praxeological approach. The authors claim that the coverage of various aspects of organizing the teaching practice, research and systematic analysis of theoretical foundations and problems of different directions have long been in sight of scholars; it is proved by the detailed analysis of scientific works by foreign and native scholars. The stage-by-stage implementation of the praxeological approach to the organization of the assistant practice for Master students of the specialty “Primary Education” and its influence on the professional development of future specialists are highlighted.
A Custom-based Crossover Technique in Genetic Algorithm for Course Scheduling Problem
Authors: Harry Saptarini Ni Gusti Ayu , Ciptayani Putu Indah , Irawan Purnama Ida Bagus
Published: September 2024

Genetic algorithm is widely used in scheduling, which crossover is one of the important operators. This paper aims to propose a custom crossover technique in genetic algorithm to solve the course scheduling problem. This technique proposes only one offspring on each crossover by choosing the best gene from each parent. The result shows that the proposed technique can be applied to solve the scheduling problem which is better compared to the one-point and two-point crossover with the best fitness value 0.0049. Its best fitness after the convergence state is more stable than two other techniques.
The Analyze of Translation Techniques in Despicable Me 3 Movie
Authors: Warda Ummu , Ashari Erwin , Sinaga Juwita Boneka , Adam
Published: September 2024

Translation is frequently employed to facilitate concept expression in the target language, accelerate language acquisition, and give us more confidence when comprehending words and expressions from other languages. Translation is not merely about converting words from one language to another; it is a comprehensive process that facilitates the expression of concepts in the target language, accelerates language learning, and boosts confidence in understanding foreign words and expressions.For this study, the researcher used a descriptive qualitative research approach. In this research the researcher  will translate a movie with the title is ‘Despicable me 3’ to analyze the 18 translation techniques used in the movie. the researcher analyze there are only 14 translation techniques that used in ‘Despicable me 3’ movie.
Production Scheduling System Based on Customer Orders at AsMedia Percetakan Nganjuk
Authors: Ananda Melyka Ayu , Handayani Wiwik
Published: September 2024

This research aims to identify the most effective production scheduling system at AsMedia Percetakan Nganjuk to reduce delays in order fulfillment. The proposed scheduling method is based on a priority rule system with the following criteria: First Come First Served (FCFS), Short Processing Time (SPT), Long Processing Time (LPT), and Earliest Due Date (EDD). Based on the results of data analysis and discussion, the First Come First Served (FCFS) and Earliest Due Date (EDD) methods are considered superior compared to the other methods. This is based on findings that show the effectiveness of the First Come First Served (FCFS) and Earliest Due Date (EDD) methods aligns with current criteria, including minimum average completion time, maximum utilization, minimum average number of jobs in the system, and minimum delays. Therefore, the researcher recommends that AsMedia Percetakan Nganjuk use the First Come First Served (FCFS) and Earliest Due Date (EDD) methods as alternative production scheduling methods. Given the relatively high average job delays with each method used, the company is deemed less effective in production scheduling. This is evident from the relatively high average job delays with each method used. Therefore, the solution the researcher can offer to AsMedia Percetakan Nganjuk is to increase the workforce and production machine capacity.
Análise de imagens do processo de divisão celular em livros de Ciências da Natureza - biologia do ensino médio: uma abordagem a partir da Teoria Cognitivista da Aprendizagem Multimídia
Authors: Guilherme da Silva Filha Josefa Maria , Das Neves Ricardo Ferreira
Published: September 2024

O ensino de Biologia compreende conceitos complexos e abstratos, cujos livros didáticos atuam como ferramentas que diminuem a abstração do conteúdo e aproximam o aluno do assunto estudado, auxiliando na aprendizagem. Com isso, este trabalho teve como objetivo analisar imagens de divisão celular em livros de Ciências da Natureza do ensino médio a partir da Teoria Cognitivista da Aprendizagem Multimídia (TCAM). Para pesquisa foram selecionados cinco livros didáticos de Ciências da Natureza e suas tecnologias aprovados pelo PNLD 2021. Com base na TCAM, as imagens do processo de divisão celular foram analisadas, e com isso identificou-se que algumas delas violam os princípios de Coerência, Sinalização e Contiguidade Espacial e ainda apresentam equívocos. Portanto, conclui-se que é muito importante que os docentes analisem os livros didáticos antes de utilizá-los em sala de aula, para evitar que esses venham comprometer a aprendizagem dos discentes.
QUANDO FALAM OS RIOS DA AMAZÔNIA: QUEM SÃO E COMO SÃO PRODUZIDOS OS ATINGIDOS POR GRANDES PROJETOS EM BARCARENA, NO PARÁ
Authors: Rodrigues Robert Damasceno Monteiro
Published: September 2024

Este artigo tem como objetivo apresentar um recorte de uma análise sobre o modo como são produzidos os afetados por grandes projetos minerais, logísticos e portuários no município de Barcarena, no estado do Pará. Partimos das histórias de vida de quatro atingidos, suas reflexões, análises, concepções e experiências em relação aos grandes projetos. A produção desses impactados é concebida na perspectiva da psicologia social crítica e, portanto, fundamenta-se nos pressupostos do materialismo histórico-dialético, por considerar os sujeitos como produtores da história e da realidade e, desse modo, de si próprios. Ao analisar as transformações nos modos de vida deles, concluímos que é indispensável considerar a realidade de suas experiências com os grandes projetos, pois é ela que materializa a totalidade dos fatores sociais, econômicos, ideológicos, objetivos e subjetivos, macro e microestruturais que se articula para determinar o modo como são produzidos.
A ILHA DA PACOCA: UMA VIAGEM PELO IMAGINÁRIO MÍTICO PRESENTE NOS ROMANCES CAFÉ CENTRAL E ANDURÁ, DE PAES LOUREIRO
Authors: De Sousa do Rosário Jocenilda Pires , De Almeida Carlos Henrique Lopes
Published: September 2024

Os dois romances de Paes Loureiro publicados até o momento, Café Central: O tempo submerso nos espelhos (2011) e Andurá, onde tudo é e não é (2020), trazem um cenário que resgata as lendas e mitos da região amazônica, onde realidade e imaginário ficam entrelaçados. A ambientação romanesca das duas obras é feita considerando espaços físicos íntimos do escritor, como a região das ilhas de Abaetetuba, em especial a ilha da Pacoca, apresentando personagens que estão diretamente ligados a esses lugares e às vivências na região amazônica.
Introdução didática ao estudo da agressão pela Análise do Comportamento
Authors: Terhoch Gabriel Bueno , Soares Pedro Felipe dos Reis
Published: September 2024

Este artigo é uma introdução didática ao estudo da agressão (comportamento agressivo) em uma perspectiva analítico-comportamental. Agressão pode ser definida como um comportamento que expõe outro(s) organismo(s) a estimulação aversiva ou que cria condições para que isso ocorra. Na condição de comportamento, a agressão está relacionada a eventos ambientais antecedentes e consequentes, e este trabalho tem como objetivo expor algumas das relações de controle já identificadas pela literatura analítico-comportamental. Primeiramente, são apontadas algumas das relações de controle do comportamento agressivo, junto a resultados experimentais que ilustram com cada relação identificada. Em seguida, o modelo experimental de agressão induzida por estimulação aversiva é brevemente apresentado e discutido. Por fim, são debatidas as implicações desse conhecimento para a prática aplicada do analista do comportamento. Destaca-se que uma perspectiva comportamental da agressão rompe com a lógica internalista que atribui apenas ao indivíduo a causa desse comportamento, permitindo maior grau de previsão e controle do comportamento agressivo a partir da ênfase à interação com variáveis ambientais. Palavras-chave: agressão, comportamento agressivo, artigo didático.
Equivalência de Estímulos na obra de Sidman: primeiro experimento, conceito e hipóteses sobre a origem do fenômeno
Authors: Azoubel Marcos Spector , Leite Emerson Ferreira da Costa , Micheletto Nilza
Published: September 2024

O objetivo deste artigo é introduzir o conceito de equivale?ncia de esti?mulos com base na obra de Sidman. Para isso, abordamos o conceito de equivalência de estímulos, apresentando o primeiro estudo sobre o tema, o contexto em que foi realizado e informações sobre a sua primeira replicação. Apresentamos também uma sumarização do conceito conforme a proposta de Sidman e seus colaboradores e algumas implicações para interpretações de fenômenos tradicionalmente entendidos como cognitivos, tais como representação simbólica, significado e pensamento lógico. Em seguida, indicamos as hipóteses desses e de outros autores sobre a origem das relações de equivalência – debate que se destaca na comunidade científica. Por fim, discutimos alguns dos caminhos abertos pela proposta teórica de Sidman para a prática e teoria em Análise do Comportamento. Desejamos que este texto ajude na construção de um debate entre as diferentes alternativas teóricas para a equivalência de estímulos consistente com as propostas dos autores, não baseado em caricaturas dessas propostas.Palavras-chave: equivalência de estímulos, Sidman, comportamento simbólico, teoria, Análise do Comportamento.
Microencapsulation of pitaya juice (Stenocereus stellatus) by spray drying using mixtures of fructans, whey protein, and modified starch as carrier agents
Authors: Soto-Dagnino María Aurora , Sánchez-Madrigal Miguel Ángel , Heredia-Olea Erick , Meléndez-Pizarro Carmen Oralia , Ortiz-Basurto Rosa Isela , Ortiz-Basurto Rosa Isela , Lardizábal-Gutiérrez Daniel , Paraguay-Delgado Francisco , Neder-Suárez David , Quintero-Ramos Armando
Published: September 2024

The proportions of agave fructans (FRU), octenyl succinate starch (OSA starch), and whey protein concentrate (WPC) as carrier agents for the encapsulation of pitaya juice composed of a mixture of pitayas red and orange were evaluated using a D-optimal mixture design. The carrier agents had a significant effect on betalains and polyphenol contents and antioxidant activity, as well as on luminosity and b* parameter of resuspended powders resulting the highest values at high proportions of WPC. Also, WPC decreased the hygroscopicity and increased the glass transition temperature with a structure characterized by fissures and porous surfaces in the powders. Optimum encapsulated powder was a mixture of 8.36 % FRU, 81.64 % WPC, and 10 % OSA starch based on reaching the maximum of betalains, polyphenols, antioxidant activity and b* parameter of color. These results suggest that a mixture of carrier agents with high proportion of WPC is a good alternative to improve pigment preservation of pitaya juice.
Entre a prescrição e a realidade: estratégias de produção e comercialização solidárias em rede de agricultores familiares: o caso da rede mandioca no Maranhão
Authors: Carneiro Marcelo Sampaio
Published: September 2024

O artigo analisa como a Cáritas Brasileira, entidade ligada à Igreja católica, preocupada com a forte presença de agricultores nas estatísticas de trabalho escravo rural, investiu na constituição de uma rede de organizações de base no estado do Maranhão, de forma a garantir a segurança alimentar e o fortalecimento econômico da agricultura familiar. Essa articulação de organizações, denominada Rede Mandioca, desenvolveu um conjunto de ações para fortalecer a produção e comercialização da farinha de mandioca, dentre as quais se destacam a realização de feiras, a organização de cooperativas e o repasse de equipamentos para o beneficiamento desse produto. A partir dos dados analisados, é possível verificar que essas ações são incorporadas de forma diferenciada pelos agricultores, apontando para a existência de diferenças entre as medidas prescritas e as estratégias definidas pelas famílias dos participantes da Rede.
Encountering and Identifying Different Forms of Domestic Violence in Shelters and Community Care Services in Finland During the COVID-19 Pandemic
Authors: Hietamäki Johanna , Kekkonen Outi , Karhinen-Soppi Anu , Kaittila Anniina , Kangas-Kalinen Annamari , Tuominen Jarno , Husso Marita
Published: September 2024

During the COVID-19 pandemic, restrictions such as lockdowns and social distancing have been used to control coronavirus. These restrictions may increase the risk of domestic violence (DV) and discourage victims from getting help. We examined the consequences that the pandemic had on different forms of DV and different victim groups of DV. An online survey of shelter clients (N= 47), interviews with clients in community care services (N= 2), and eight focus group interviews with professionals (N =27) working in shelters and community care services were used for data. We used a mixed-methods approach in the analysis, which showed that clients in shelters reported more violence during the pandemic than prepandemic. Psychological, controlling, and financial violence increased the most during the pandemic, according to the survey data. Coercive control was the most visible type of violence from the perspective of three vulnerable groups: intimate partners, children, and migrants. The research findings will help us arrange services to identify and better manage pandemic lockdown-associated violence.
Acute Health System-Level Interventions for Identification and Management of Domestic Abuse: Preliminary Interrupted Time Series Evaluation
Authors: Melendez-Torres G. J. , Hepworth E. , Sloane V. , Jackson S. , Nicholas R. , Cohen C. E.
Published: September 2024

This preliminary interrupted time series analysis evaluated different interventions to improve identification of victim-survivors of domestic abuse in one U.K. National Health Service trust, focusing on emergency department, sexual health services and human immunodeficiency virus care, and obstetrics and gynecology. This analysis demonstrated that while system-level interventions can improve identification of domestic abuse in clinical contexts, the exact nature of interventions most likely to be effective may vary in different clinical contexts. For example, none of the modeled interventions generated significant impacts in emergency department contexts, and estimates were close to the null in all cases, but routine inquiry demonstrated effectiveness in sexual health services, while implementation generated improved effectiveness in the obstetrics and gynecology setting.
Transitioning from Full-time Employment to Entrepreneurship: How Networking Affect Entrepreneurial Survival and Success
Authors: Kumar Satish
Published: September 2024

This career shift from a salaried job to entrepreneurship is a significant change, having a number of associated challenges and opportunities. This paper examines the role of networking in enabling an entrepreneur to negotiate the challenges and succeed in his transition process. The influence of these networking activities on an individual's ability to navigate the intricate aspects involved in entrepreneurship, in enhancing the chances of survival and success in competitive business environments, is shown through analysis of already existing research and empirical evidence.

In this paper, the theoretical bases of networking in entrepreneurship are analyzed as a way to explain its importance for access to crucial resources, information, and opportunities while carrying out entrepreneurial activities. Coupling the findings of previous studies, this paper will show how and why networking can help realize the transition from full-time employment to entrepreneurship and provide expansion and durability for nascent ventures. This work will further relate research on the different types of networks, such as social networks, professional societies, mentorship programs, entrepreneurial communities, and their inferences on entrepreneurial outcomes. The research was able to delve deeper into the details of networking strategies and the implications it had on entrepreneurial survival and success in pointing out suggestions to those intending to start a business while maintaining a full-time job.  
This paper makes a strong contribution to the entrepreneurship literature in respect of demonstrating the contribution of networking within the transition process and making the processes more likely to result in successful new businesses. Results show clearly the need for strategic networking activities by those moving from ordinary employment into entrepreneurship; this is not a passive activity, so there is an obvious requirement for the networking of active processes with different networks in order to connect with resources and opportunities that would support sustainable enterprise growth.
Recognising Heritage for Human Rights and Development
Authors: Shahab Sofaya
Published: September 2024

This study focuses on the ways in which the Cultural Protection Fund intersects with the Integrated Review (IR), the objectives of Overseas Development Assistance (ODA) funding and the Foreign, Commonwealth and Development Office’s (FDCO) International Development Strategy (IDS). From the research, it is possible to see how heritage interventions, such as the CPF - and most specifically its community oriented approach - acts as a mode of operating within other spaces and areas. This includes promoting open societies by enhancing understanding and tolerance of other cultures and groups, furthering opportunities for women and girls, and upholding human rights and identities by establishing connections to place and preserving cultural and religious practices.
Competencias transversales del tutor clínico de las especializaciones en Enfermería: resultados de la autoevaluación
Authors: Montero-Díaz Rodrigo , González-Juárez Graciela , Ponce-Gómez Gandhy
Published: September 2024

Objective: Analyze the transversal competencies of clinical tutors through diagnostic self-assessment to identify strengths and areas of opportunity in clinical tutoring.
Material and methods: This is a quantitative, descriptive and cross-sectional study. The sample consisted of 95 clinical tutors hired to teach academic activities related to clinical practice in the specializations and who were willing to participate. A self assessment scale was designed that contains three dimensions and subdimensions of transversal competence and was validated by expert judging and a pilot study. It was applied through the Google Forms platform. The total variable was calculated and the corresponding percentages were obtained.
Results: A differentiated diagnosis was made in strengths and areas of opportunity in the transversal competencies of the clinical tutor. In general, the self-assessment demonstrates that high percentages in the dimensions considered with not significant variations in these.
Conclusions: The transversal competencies of the clinical tutor demand differentiated training to achieve a profile that contributes to the development of transversal competencies such as the ability to design learning scenarios, specialized care and the ability to evaluate learning in real practice scenarios.
 Keywords: Mentor; Preceptorship, Tutor; Competency-based education.
INCONSTITUCIONALIDADE VITANDA: o novo regime jurídico das instituições de educação e de assistência social previsto no art. 12, da Lei n. 9532/97
Authors: Carvalho Paulo de Barros
Published: September 2024

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PRINCÍPIO DA INSIGNIFICÂNCIA NO DIREITO PENAL
Authors: Arruda Rejane Alves de
Published: September 2024

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A PROBLEMÁTICA ÉTICO-JURÍDICA DA REPRODUÇÃO HUMANA ASSISTIDA E SEUS REFLEXOS NO DIREITO CIVIL E CONSTITUCIONAL
Authors: Guimarães Luís Paulo Cotrim
Published: September 2024

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AS ALDEIAS INDÍGENAS FORAM TRANSFORMADAS NUM ESTOQUE ESTRATÉGICO DE MÃO-DE-OBRA BARATA E DESQUALIFICADA
Authors: Pauletti Maucir
Published: September 2024

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EFFECT OF MORINGA (Moringa oleifera) LEAF EXTRACT ON IN VITRO INHIBITION OF Candida albicans BIOFILM
Authors: Sulistyani Herastuti , Sulastri Siti , Agustina Dewi , A'yun Quroti
Published: September 2024

Background: Oral candidiasis is an opportunistic infection in the oral cavity. This infection is caused by the fungus Candida albicans. The most important virulent attribute of this fungus is its ability to form biofilms, which can adhere to mucosa, epithelial lining, organs, prostheses or dentures. The formed biofilm is resistant to antifungal drugs. Objectives: The purpose of this study was to determine the effect of Moringa (Moringa oleifera) leaf extract on the inhibition of Candida albicans biofilm formation in vitro. Methods: This type of research is experimental study using post tests with control group design. Fungus used in this study was Candida albicans ATCC 10231. Determination of minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were conducted by microdilution method. Inhibition test of C. albicans biofilm formation was carried out using the polystyrene microplate assay method. Concentration of extracts used in this study were 12.5%, 6.25%, 3.13% and 1.57%. Inhibitory activity of biofilm was measured using a crystal violet (CV) assay. Results: The results showed that MIC of Moringa leaf extract against the fungus C. albicans was at a concentration of 6.25%. Moringa leaf extract starting at a concentration of 3.13% already has had ability to inhibit formation of C. albicans biofilm. Conclusion:  It can be concluded that Moringa leaf extract can inhibit formation of Candida albicans biofilm, so it can be developed as an alternative herbal ingredient to prevent oral candidiasis.EFFECT OF MORINGA (Moringa oleifera) LEAF EXTRACT ON IN VITRO INHIBITION OF Candida albicans BIOFILM
THE EFFECTIVENESS OF CINNAMON BARK EXTRACT PASTE (Cinnamomum burmanii) IN ELIMINATING Candida albicans IN THERMOPLASTIC NYLON
Authors: Sinaga Gloria Meyana , Arifin Rahmad , Diana Sherli , Wardani Ika Kusuma , Erlita Isyana
Published: September 2024

Background: One type of denture base that is widely used is thermoplastic nylon. Thermoplastic nylon not cleaned regularly will cause food residue to stick and give rise to fungi such as Candida albicans. Mechanical cleaning methods are more effective at removing microbes. However, regular toothpaste contains abrasive ingredients that can scratch dentures. Extracts from cinnamon bark can be used because they contain ingredients that can inhibit the growth of Candida albicans colonies. Purpose: To analyze the antifungal activity of using cinnamon bark (Cinnamomum burmanii) extract paste to eliminate Candida albicans on thermoplastic nylon. Methods: This research is purely experimental, using a pretest-posttest with a control group design. This study used 27 thermoplastic nylon plates measuring 65x10x3mm, which were divided into 3 groups, namely the cinnamon bark extract paste group with a concentration of 50%, Fresh 'n Brite paste as a positive control, distilled water as a negative control. Results: The results of the Kruskal-Wallis test show an effect based on treatment in each group. Conclusion: Fresh ‘n Brite denture paste as a positive control is more effective in eliminating Candida albicans on thermoplastic nylon than cinnamon bark extract paste with a concentration of 50% and distilled water as a negative control.
BASE SURFACE TEMPERATURE OF BULK FILL RESIN COMPOSITE WITH DIFFERENT THICKNESS
Authors: Harahap Sefty Aryani , Yudhit Astrid , Febyola Vivi Niwani , Harahap Naspati , Candra Graciella
Published: September 2024

Background: The material thickness is one factor that influences the polymerization of resin composites. Bulk fill resin composite is an efficient dental resin composite restoration material because it can be cured to a thickness of up to 4-5 mm. The thickness of the material can also affect the temperature rise, while maintaining the temperature is very important because a significant increase can damage the pulp. Purpose: This research aimed to analyze the base surface temperature of bulk fill resin composite with different thicknesses. Methods: Thirty bulk fill resin composite samples with a diameter of 5 mm were divided into three groups with different thicknesses, namely group I (3 mm), group II (4 mm), and group III (5 mm). Each group of samples was cured using an LED Light Curing Unit for 20 seconds, and carried out simultaneously with the measurement of the base surface temperature using a type-K digital thermocouple. Data analyzed using One Way ANOVA and LSD post hoc tests. Results: The mean and standard deviation of the base surface temperature of bulk fill resin composite in groups I, II, and III, respectively, is 37.56 ± 1.06oC, group II 36.89 ± 1.23oC, and group III 36.00 ± 1.2 oC. It showed significantly different between the groups (p<0,05). Conclusion: The thicker the bulk fill resin composite, the lower the base surface temperature.
EFFECT OF GALAM LEAF EXTRACT AND TRI-CALCIUM SILICATE CEMENT ON NEUTROPHIL CELLS IN WISTAR RAT PULP
Authors: Putra Fedriko Gamaliel , Diana Sherli , Dewi Nurdiana , Wasiaturrahmah Yusrinie , Carabelly Amy Nindia
Published: September 2024

Background: Pulp capping is a method of sealing the pulp chamber in teeth with cavities that extend to the pulp. Direct pulp capping involves applying a material directly onto the exposed pulp tissue. Tri-calcium silicate cement (Ca3SiO5) is commonly used due to its nanoparticle mineral composition, but it can cause continued inflammation. Galam leaf (Melaleuca cajuputi) is known for its anti-inflammatory properties, owing to secondary metabolites like alkaloids, flavonoids, polyphenols, and saponins, potentially compensating for the drawbacks of tri-calcium silicate cement. Purpose: To determine the effect of combining Galam leaf extract (Melaleuca cajuputi subsp. Cumingiana (Turz) Barlow) with tri-calcium silicate cement as a direct pulp capping material on neutrophil cell count in the pulp of Wistar rats (Rattus norvegicus). Methods: This pure experimental study used a posttest-only control design. Thirty-six Wistar rats were divided into nine groups: one received a combination of 100% Galam leaf extract and tri-calcium silicate cement; one positive control group received tri-calcium silicate cement alone; and one negative control group received direct placement with glass ionomer cement (GIC). The neutrophil cell count was assessed on days 1, 2, and 3. Results: Two-way ANOVA results indicated a significant effect based on treatment and time (p < 0.05). Further analysis with the Post Hoc Bonferroni test (p < 0.05) revealed differences in neutrophil cell counts across nearly all groups on days 1, 2, and 3. Conclusion: The combination of 100% Galam leaf extract and tri-calcium silicate cement significantly reduced neutrophil cell counts compared to both positive and negative control groups on days 1, 2, and 3, indicating anti-inflammatory effect.
Exploring intra-specific variability as an adaptive strategy to climate change: Response of 21 grapevine cultivars grown under drought conditions
Authors: Serrano Parra Argimiro Sergio , Martínez Gascueña Jesús , Alonso Gonzalo L. , Cebrián Tarancón Cristina , Mena Morales Adela , Chacón Vozmediano Juan L.
Published: September 2024

In recent decades, as a consequence of climate change, grape ripening is occurring under warmer and drier conditions, resulting in losses in the yield and quality of wine grapes. Several alternatives may reduce these negative effects. One that stands out for its potential for long-term adaptation is the selection of better-adapted plant material. For this purpose, during two consecutive years, several agronomic and quality parameters were recorded in 21 grapevine cultivars grown under two water stress levels (moderate and severe). The results revealed that some cultivars considered a minority, as well as others recently recovered from the viticultural heritage that had almost become extinct, could offer a similar and even better response to drought than other widespread cultivars. In particular, Maquías, Montonera del Casar, and Tortozona Tinta stood out for their high total acidity; Tinto Fragoso and Tinto Velasco for their high anthocyanin concentration; and Albillo Dorado and Moscatel Serrano for their high varietal aromatic potential. These cultivars could contribute to diversifying varietal offerings and to maintaining the sustainability of the wine sector in the coming decades.
PELATIHAN WORK LIFE BALANCE UNTUK STRES KERJA PADA PERAWAT WANITA
Authors: Briliani Afifah Tiara , Husna Aftina Nurul
Published: September 2024

Work stress is a common issue experienced by nurses, particularly married female nurses. Literature suggests that work-life balance enhancement can mitigate work stress. This study aims to assess the effectiveness of outsourcing-based work-life balance training in reducing job stress among married female nurses. A quasi-experimental one-group pretest-posttest design was conducted with 10 married female nurses. Data were collected using psychological scales (pretest and posttest), daily journal entries, follow-up interviews, and post-training evaluations. Data were analyzed using paired sample t-tests with IBM SPSS Statistics 25. The data analysis showed a significant result (t(9) = 3.929, p < 0.05, 95% CI = 2.885-10.715), indicating that work-life balance training is effective in reducing job stress among married female nurses.
Monitoring Macroinvertebrates as Bioindicators and Water Physicochemical Parameters in the Tambak Rejo River, Sidoarjo.
Authors: Robbi Adinda Atthiyatur , Munfarida Ida , Oktorina Sarita , Suprayogi Dedy , Setyowati Rr Diah Nugraheni
Published: September 2024

Sungai Tambak Rejo merupakan sungai yang berada di desa Tambak Rejo, Kabupaten Sidoarjo. Sungai Tambak Rejo, merupakan sungai utama yang mengaliri tiga kelurahan yaitu tambak sumur, tambak rejo dan tambak sawah. Berbagai karakteristik lokasi menjadikan sungai ini memiliki berbagai limbah yang dihasilkan baik limbah domestik, limbah industri dan limbah pertanian. Hal ini tentunya dapat menyebabkan penurunan kuaitas air sungai, apabila limbah yang dihasilkan tidak diolah dengan benar. Pemantauan makroinvertebrata sebagai bioindikator kualitas air sungai merupakan tujuan penelitian ini, dimana biota ini dapat digunakan sebagai indikator biologis karena adanya habitat dan keberadaannya sangat dipengaruhi secara langsung di dalam perairan. Pengukuran parameter fisik-kimia air juga dilakukan untuk menyesuaikan kualitas air sungai dengan baku mutu yang telah ditetapkan, paramet yang diukur ialah Ph, Suhu, TSS, BOD, COD dan Kadar mangan. analisis makroinvertebrata menggunakan dua metode yakni, metode indeks biotilik dan metode indeks biotik,  Pada Indeks Biotilik, Titik I dan Titik II dikategorikan sebagai sungai tercemar sedang dan Titik III diktegorikan sebagai sungai tercemar ringan. Pada Indeks Biotik, Titik I tergolong pada perairan kotor sedang Titik II tergolong pada perairan kotor sedang dan berat. beberapa parameter fisika-kimia yang tidak sesuai dengan baku mutu, yakni BOD, pada titik I, titik II. COD, pada titik I-III.
Parent Emotion Socialization (PES) and Emotion Variables in Children and Adolescents: A Systematic Review
Authors: Makruf Herlin Asfarina , Iswinarti  , Hasanati Nida
Published: September 2024

Parent emotion socialization (PES), a response used when reacting to the emotional expression of children, is classified into supportive and non-supportive categories and varies at each stage of development. In this context, emotion, which is measured based on a strong theoretical foundation, plays an important role in children and adolescent development in terms of social functioning, academic achievement, and the development of psychopathology. The status as a single domain of study depends on each theoretical perspective applied. Based on prediction, the types of related variables also vary depending on each theoretical perspective. Therefore, this study aimed to fill the gap of reviews on the types of emotion variables. The association between the dynamics of emotion variables and PES was determined by analyzing 15 international journals. The results showed that emotion regulation was the variable most associated with PES in children and adolescents, serving as a moderator or vice versa. Other variables included self-conscious emotion, social and emotional adjustment, expression of emotion, negative emotionality/lability, and emotion processing. In conclusion, practitioners were provided with considerations regarding the measurement, study, and development of PES topics and various emotion variables.
The Determinants of Academic Resilience among Undergraduate Students Post COVID-19
Authors: Daulay Nurussakinah
Published: September 2024

This study examines the determinants of students academic resilience, particularly the impact of social support and gratitude in the aftermath of the COVID-19 pandemic. A total of 240 students were selected as participants, with data collected through surveys by distributing online questionnaires. The instruments adopted were the Multidimensional Scale of Perceived Social Support, The Gratitude Questionnaire-6, and the Academic Resilience Scale. Furthermore, the data collected were analyzed using multiple regression and path analysis. The results showed that: 1) social support did not influence gratitude (F(1,238) = .488, p = .485; p>0.01) and academic resilience (F(1,238) = .568, p = .452; p>0.01), 2) gratitude had a significant impact on academic resilience (F(1,238) = 6.854, p = .009; p<0.01). Despite reduced social support from parents, lecturers, and the community during the pandemic, internal protective factors proved instrumental in navigating challenging circumstances and fostering the cultivation of academic resilience.