bluuebunny/crossref_metadata_2025 huggingface dataset:
OXIDATIVE STRESS AND THE BIOLOGICAL AND CHEMICAL PROCESSES IN HEALTH
Authors: Santos Julia Matzenbacher
Published: October 2020

N/A
L-GLUTAMINE SUPPLEMENTATION ASSOCIATED WITH MODERATE AEROBIC TRAINING IMPROVES BIOMETRIC, GLYCEMIC PROFILE AND THE ANTIOXIDANT DEFENSE
Authors: Bender dos Santos Analú , Corrêa Costa-Beber Lílian , De Pelegrin Basso Eloisa Gabriela , Brendler Goettems Fiorin Pauline , Bueno Basso Renan Daniel , Machado Sulzbacher Maicon , Stela Ludwig Mirna , Heck Thiago Gomes
Published: October 2020

Introduction: L-glutamine is a non-essential amino acid, whose intrinsic pool of appears to be depleted during catabolic conditions, such as intense or high duration exercise, and to avoid the exercise- related benefits. Therefore, its supplementation could provide an additional source of L-glutamine and prevent these effects. However, the oral intake of its free form has been discouraged, despites of some evidences reporting positive effects. Objective: to verify whether the L-glutamine supplementation (in its free form) could provide an additional improvement in biometric, glycemic and redox parameters, in animals undergoing moderate aerobic training (MAT). Methods: 28 Swiss male mice were divided into four groups: Cont (n=7), Ex (n=7), Glut (n=8), and Ex+Glut (n=6). Glut and Ex+Glut received gastric gavage of L-glutamine (1g/kg), while Cont and Ex groups received 100 µL of PBS one hour before exercising, five days/week, six weeks. Ex and Ex+Glut underwent moderate swimming, while Cont and Glut remained sedentary, for the same period. Mice started swimming with 2% of body weight attached to the tail during 20 min, and ended the experiment with 4% during 60 min. Results: L-glutamine supplementation increased the gastrocnemius mass and improved the glucose tolerance in animals submitted to MAT. It improved the antioxidant status in gastrocnemius, liver and pancreas, and declined it in adipose tissue in animals undergoing MAT. The drop of adipose antioxidant defense was associated with adiposity, while pancreas antioxidant activity was inversely associated with the glucose intolerance. Conclusion: L-glutamine (free form) improves biometric and glucose parameters, and enhances antioxidant activities.
Antimicrobial resistance screening and profiles: a glimpse from the South African perspective
Authors: Genthe B. , Ndlela L. , Madlala T.
Published: October 2020

According to the Centre for Disease Dynamics Economics and Policy, South Africa represents a paradox of antibiotic management similar to other developing countries, with both overuse and underuse (resulting from lack of access) of antibiotics. In addition, wastewater reuse may contribute towards antibiotic resistance through selective pressure that increases resistance in native bacteria and on clinically relevant bacteria, increasing resistance profiles of the common pathogens. Sediments of surface water bodies and wastewater sludge provide a place where antibiotic resistance genes are transferred to other bacteria. Crop irrigation is thought to be a potential source of exposure to antibiotic-resistant bacteria through the transfer from the water or sludge into crops. The objectives of this study were to examine the antibiotic-resistance profiles of Escherishia coli from three agricultural locations in the Western Cape, South Africa. Using a classical microbiology culture approach, the resistance profiles of E. coli species isolated from river water and sediments, farm dams and their sediments and a passive algal wastewater treatment ponds and sediment used for crop irrigation were assessed for resistance to 13 commonly used antibiotics. Randomly selected E. coli isolates from the sediment and water were tested for resistance. 100% of E. coli isolates were resistant to sulphamethoxazole, highlighting its relevance in the South African context. In river water and farm dam samples, only the E. coli isolated from sediment were found to be resistant to fluoroquinolone or fluorifenicol. In the wastewater treatment ponds, the resistance profiles of E. coli isolated from sediments differed from those isolated from effluent, with 90% of the effluent isolates being resistant to ampicillin. Isolates from the sediment were less resistant (40%) to ampicillin, whereas all the isolates from the pond water and sediment samples were resistant to sulphamethoxazole. These results illustrate the importance of developing a better understanding of antibiotic resistance in agriculture and wastewater scenarios to ensure remedial measures take place where the greatest benefit can be realised especially in countries with limited financial and infrastructural resources. Moreover, the potential for passive algal treatment as an effective, feasible alternative for wastewater treatment is highlighted, with comparable resistance profiles and a reducing overall resistance in the sediment samples.
A combined probabilistic framework to support investment appraisal under uncertainty in desalination projects: an application to Kuwait's water/energy nexus
Authors: Skourtos M. , Damigos D. , Kontogianni A. , Tourkolias C. , Marafie A. , Zainal M.
Published: October 2020

Quantifying uncertainty over technologies, costs, and prices that stem from site-specific conditions, technological particularities and future projections is an important element in the investment appraisal of desalination facilities. Yet, the majority of economic assessments in the field of desalination plants, so far, use deterministic estimation methods based on ‘best guess’ estimates and ceteris paribus sensitivity analyses. Aiming to fill this gap, this paper introduces a new approach towards comparing alternative technological options for desalination facilities under uncertainty based on the Levelized Cost of Water (LCOW). The proposed framework combines Monte Carlo simulations with scenario analysis and random-walk-based models to account for the cone of uncertainty of the LCOW. For purely illustrative purposes, five alternative combinations of desalination technologies and energy sources are examined in the State of Kuwait. The findings show that the proposed framework, although it cannot eliminate uncertainty, can assist decision-makers in managing it by framing the range of possible outcomes of the LCOW. In this way, it offers an insight into the accuracy of the estimates and allows the validation of the impact of risks and uncertainties against the acceptable tolerance level. Yet, several issues need to be addressed in future research.
Eğitimde Veli Katılımına Yönelik Çalışmaların İncelenmesi
Authors: KAHRAMANOGLU Recep , YÜCETAŞ ARTAN Gözde
Published: October 2020

Bu çalışmada 2000-2018 yılları
arasında eğitimde veli katılımı konusunda yapılmış çalışmaların incelenmesi
amaçlanmaktadır. Bu amaç doğrultusunda 2000-2018 yılları arasında eğitimde veli
katılımı konusunda yazılmış makale, yüksek lisans ve doktora tezinden oluşan
144 çalışma incelenmiştir. Bu dokümanlara ulaşmak için Ulusal Tez Merkezi,
Google Akademik, Ulakbim, Dergipark gibi sitelerde alan yazın taraması
yapılmıştır. Bu çalışmalar amaç, yapıldığı yer, yayın yılı, yapıldığı kademe,
çalışma türü, çalışma yöntemi, çalışma deseni ve veri toplama araçları alt
problemleriyle ele alınmıştır. Bu çalışmada güvenilir bilgi elde etmek amacıyla
nitel araştırma modeli kullanılmıştır. Nitel araştırma modelinden doküman
incelemesi yöntemi kullanılmıştır. Bu yöntem ile eğitimde veli katılımı
konusunda yapılan çalışmalardan elde edilen veriler betimsel analiz yöntemi ile
analiz edilmiştir. 144 çalışmaya ait veriler sistemli ve açık şekilde
betimlenmiş, açıklanmış, yorumlanmış ve bazı sonuçlara ulaşılmıştır. Çalışmanın
sonucunda eğitimde veli katılımı konusunda daha çok nicel çalışma yapıldığı,
tarama deseni kullanıldığı, okul öncesi eğitim kademesinde yoğunlaştığı
görülmüştür. Çalışmalar daha çok Batı illerde yapılmış ve makale olarak
yazılmıştır. Son yıllarda veli katılımı konusunda yapılan çalışmalarda artış
olduğu ortaya çıkmıştır.
DESEMPENHO DE PLACAS DE FLUXO DE CALOR NO SOLO EM ÁREA COM CAPIM BRAQUIÁRIA
Authors: Couto João Paulo Chaves , Oliveira Aureo Silva de , Borges Tatyana Keyty de Souza , Pereira Monikuelly Mourato
Published: October 2020

As placas de fluxo de calor no solo são utilizadas em estudos de balanço de energia e demanda hídrica. Objetivou-se, com este estudo avaliar dois diferentes modelos de placas de fluxo de calor no solo, HFT3.1 e HFP01, denominadas REBS e HUKS para período de solo seco na Universidade Federal do Recôncavo da Bahia - UFRB, Campus Cruz das Almas, entre outubro e dezembro de 2015. Os valores R², para o período de solo seco, foram de 99,34; 96,86 e 99,04 % comparando placas do modelo HFT3.1 (REBS1 x REBS2), do modelo HFP01 (HUKS1 x HUKS2) e entre os modelos REBS e HUKS respectivamente. O modelo REBS apresentou maior amplitude de medição em relação ao modelo HUKS, sendo que a diferença pode ser atribuída às condições de instalação das placas.
Fast-Dissolving Solid Dispersions for the Controlled Release of Poorly Watersoluble Drugs
Authors: Tran Phuong H.L. , Lee Beom-Jin , Tran Thao T.D.
Published: October 2020

Solid dispersions offer many advantages for oral drug delivery of poorly water-soluble drugs over
other systems, including an increase in drug solubility and drug dissolution. An improvement in drug absorption
and the higher bioavailability of active pharmaceutical ingredients in the gastrointestinal tract have been reported
in various studies. In certain circumstances, a rapid pharmacological effect is required for patients. Fastdissolving
solid dispersions provide an ideal formulation in such cases. This report will provide an overview of
current studies on fast-dissolving solid dispersions, including not only solid dispersion powders with fast dissolution
rates but also specific dose form for the controlled release of poorly water-soluble drugs. Specifically,
the applications of fast-dissolving solid dispersions will be described in every specific case. Moreover, pharmaceutical
approaches and the utilization of polymers will be summarized. The classification and analysis of fastdissolving

solid dispersions could provide insight into strategies and potential applications in future drug delivery
developments.
Research and Patents on Coronavirus and COVID-19: A Review
Authors: Aranda Pilar , Wicklein Bernd , Ruiz-Garcia Cristina , Martín-Sampedro Raquel , Darder Margarita , del Real Gustavo , Ruiz-Hitzky Eduardo
Published: October 2020

Background:

COVID-19 pandemic is a global problem that requires the point of view of basic
sciences and medicine as well as social, economics and politics disciplines. Viral particles of
coronaviruses including SARS-CoV-2 as well as other enveloped viruses like influenza virus could be
considered as an approximation to functional core-shell nanoparticles and therefore, their study enters
the realm of nanotechnology. In this context, nanotechnology can contribute to alleviate some of the current
challenges posed by COVID-19 pandemic.

Methods:

The present analysis contributed to diverse sources of general information, databases on scientific
literature and patents to produce a review affording information on relevant areas where as
nanotechnology has offered response to coronavirus challenges in the past and may be relevant now, and
has offered an update of the current information on SARS-CoV-2 and COVID-19 issues.

Results:

This review contribution includes specific information including: 1) An introduction to current research
on nanotechnology and related recent patents for COVID-19 responses; 2) Analysis of nonimmunogenic
and immunogenic prophylaxis of COVID-19 using Nanotechnology; 3) Tools devoted to detection
& diagnosis of coronaviruses and COVID-19: the role of Nanotechnology; and 4) A compilation on
the research and patents on nanotechnology dealing with therapeutics & treatments of COVID-19.

Conclusion:

Among the increasing literature on COVID-19, there are few works analyzing the relevance
of Nanotechnology, and giving an analysis on patents dealing with coronaviruses that may provide
useful information on the area. This review offers a general view of the current research investigation
and recent patents dealing with aspects of immunogenic and non-immunogenic prophylaxis, detection
and diagnosis as well as therapeutics and treatments.
Comparison of Interface Pressure, Contact Surface Area, and Percent Area of Coverage Between Two Suture Configurations for Hill-Sachs Remplissage
Authors: Pozo René , Reinares Felipe , Espinosa Maximiliano , Guarachi Juan Pablo , Sacre Michelle , Toro Felipe
Published: October 2020

Purpose:

To compare maximum contact pressure, contact surface area, and the percent area of coverage of the bone-tendon interface in the remplissage procedure between two different suture configurations (independent mattress versus double-pulley).

Methods:

A sample size of seven specimens per group was defined by a 96% power analysis.

Hill-Sachs lesions were created in all fourteen ex vivo ovine shoulders, corresponding to a 30% defect of the axial diameter of the humeral head (significant lesion according to literature). The defects were repaired using the remplissage technique applying one of the two randomly chosen suture configurations: two independent mattress sutures or a double-pulley. The contact pressure and contact surface area, as well as percent defect coverage, were recorded using a film sensitive to these parameters. Independent nonparametric tests (Mann-Whitney) were used for the statistical analysis.

Results:

The double-pulley group exhibited an average pressure of 0.128 ± 0.018 mPa, the contact surface of 0.199 ± 0.044 cm2, and 41.97 ± 9.8% defect coverage. The independent mattress group showed an average pressure of 0.102 ± 0.01 mPa, the contact surface of 0.081 ± 0.041 cm2, and defect coverage of 15.6 ± 8.1%. All three parameters were statistically superior in the double-pulley group (p=0.038, p=0.008, and p=0.008, respectively)

Conclusion:

The remplissage technique using the double-pulley configuration, presented superior biomechanical characteristics, in terms of contact pressure, contact area, and percent coverage of the defect, compared to the simple independent mattress configuration.
Osteonecrosis of the Femoral Medial Condyle Due to Leg Length Discrepancy After A Traffic Accident
Authors: Kusano Wataru , Mine Takatomo , Ihara Koichiro , Kawamura Hiroyuki , Shinohara Michio , Kuriyama Ryutaro , Tominaga Yasuhiro
Published: October 2020

Untreated leg length discrepancy can cause spontaneous osteonecrosis of the knee, which is associated with subchondral insufficiency fractures of the knee and progression or onset of osteoarthritis of the knee. Spontaneous osteonecrosis of the knee can be secondary to cartilage loss or additional subchondral changes. A 40-year-old female underwent opening-wedge high tibial osteotomy and osteochondral grafting for osteonecrosis of the femoral medial condyle and osteoarthritis of the knee caused by leg length discrepancy after a traffic accident. High tibial osteotomy and cartilage restoration are often considered for the treatment of knee osteonecrosis with cartilage damage in younger patients.
A Tablet App for Handwriting Skill Screening at the Preliteracy Stage: Instrument Validation Study
Authors: Dui Linda Greta , Lunardini Francesca , Termine Cristiano , Matteucci Matteo , Stucchi Natale Adolfo , Borghese Nunzio Alberto , Ferrante Simona
Published: October 2020

Background

Difficulties in handwriting, such as dysgraphia, impact several aspects of a child’s everyday life. Current methodologies for the detection of such difficulties in children have the following three main weaknesses: (1) they are prone to subjective evaluation; (2) they can be administered only when handwriting is mastered, thus delaying the diagnosis and the possible adoption of countermeasures; and (3) they are not always easily accessible to the entire community.

Objective

This work aims at developing a solution able to: (1) quantitatively measure handwriting features whose alteration is typically seen in children with dysgraphia; (2) enable their study in a preliteracy population; and (3) leverage a standard consumer technology to increase the accessibility of both early screening and longitudinal monitoring of handwriting difficulties.

Methods

We designed and developed a novel tablet-based app Play Draw Write to assess potential markers of dysgraphia through the quantification of the following three key handwriting laws: isochrony, homothety, and speed-accuracy tradeoff. To extend such an approach to a preliteracy age, the app includes the study of the laws in terms of both word writing and symbol drawing. The app was tested among healthy children with mastered handwriting (third graders) and those at a preliterate age (kindergartners).

Results

App testing in 15 primary school children confirmed that the three laws hold on the tablet surface when both writing words and drawing symbols. We found significant speed modulation according to size (P<.001), no relevant changes to fraction time for 67 out of 70 comparisons, and significant regression between movement time and index of difficulty for 44 out of 45 comparisons (P<.05, R2>0.28, 12 degrees of freedom). Importantly, the three laws were verified on symbols among 19 kindergartners. Results from the speed-accuracy exercise showed a significant evolution with age of the global movement time (circle: P=.003, square: P<.001, word: P=.001), the goodness of fit of the regression between movement time and accuracy constraints (square: P<.001, circle: P=.02), and the index of performance (square: P<.001). Our findings show that homothety, isochrony, and speed-accuracy tradeoff principles are present in children even before handwriting acquisition; however, some handwriting-related skills are partially refined with age.

Conclusions

The designed app represents a promising solution for the screening of handwriting difficulties, since it allows (1) anticipation of the detection of alteration of handwriting principles at a preliteracy age and (2) provision of broader access to the monitoring of handwriting principles. Such a solution potentially enables the selective strengthening of lacking abilities before they exacerbate and affect the child’s whole life.
Mobile and Wearable Technology for the Monitoring of Diabetes-Related Parameters: Systematic Review (Preprint)
Authors: Rodriguez-León Ciro , Villalonga Claudia , Munoz-Torres Manuel , Ruiz Jonatan R , Banos Oresti
Published: October 2020

BACKGROUND

Diabetes mellitus is a metabolic disorder that affects hundreds of millions of people worldwide and causes several million deaths every year. Such a dramatic scenario puts some pressure on administrations, care services, and the scientific community to seek novel solutions that may help control and deal effectively with this condition and its consequences.

OBJECTIVE

This study aims to review the literature on the use of modern mobile and wearable technology for monitoring parameters that condition the development or evolution of diabetes mellitus.

METHODS

A systematic review of articles published between January 2010 and July 2020 was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Manuscripts were identified through searching the databases Web of Science, Scopus, and PubMed as well as through hand searching. Manuscripts were included if they involved the measurement of diabetes-related parameters such as blood glucose level, performed physical activity, or feet condition via wearable or mobile devices. The quality of the included studies was assessed using the Newcastle-Ottawa Scale.

RESULTS

The search yielded 1981 articles. A total of 26 publications met the eligibility criteria and were included in the review. Studies predominantly used wearable devices to monitor diabetes-related parameters. The accelerometer was by far the most used sensor, followed by the glucose monitor and heart rate monitor. Most studies applied some type of processing to the collected data, mainly consisting of statistical analysis or machine learning for activity recognition, finding associations among health outcomes, and diagnosing conditions related to diabetes. Few studies have focused on type 2 diabetes, even when this is the most prevalent type and the only preventable one. None of the studies focused on common diabetes complications. Clinical trials were fairly limited or nonexistent in most of the studies, with a common lack of detail about cohorts and case selection, comparability, and outcomes. Explicit endorsement by ethics committees or review boards was missing in most studies. Privacy or security issues were seldom addressed, and even if they were addressed, they were addressed at a rather insufficient level.

CONCLUSIONS

The use of mobile and wearable devices for the monitoring of diabetes-related parameters shows early promise. Its development can benefit patients with diabetes, health care professionals, and researchers. However, this field is still in its early stages. Future work must pay special attention to privacy and security issues, the use of new emerging sensor technologies, the combination of mobile and clinical data, and the development of validated clinical trials.
Preliminary Screening for Hereditary Breast and Ovarian Cancer Using a Chatbot Augmented Intelligence Genetic Counselor: Development and Feasibility Study (Preprint)
Authors: Sato Ann , Haneda Eri , Suganuma Nobuyasu , Narimatsu Hiroto
Published: October 2020

BACKGROUND

Breast cancer is the most common form of cancer in Japan; genetic background and hereditary breast and ovarian cancer (HBOC) are implicated. The key to HBOC diagnosis involves screening to identify high-risk individuals. However, genetic medicine is still developing; thus, many patients who may potentially benefit from genetic medicine have not yet been identified.

OBJECTIVE

This study’s objective is to develop a chatbot system that uses augmented intelligence for HBOC screening to determine whether patients meet the National Comprehensive Cancer Network (NCCN) BRCA1/2 testing criteria.

METHODS

The system was evaluated by a doctor specializing in genetic medicine and certified genetic counselors. We prepared 3 scenarios and created a conversation with the chatbot to reflect each one. Then we evaluated chatbot feasibility, the required time, the medical accuracy of conversations and family history, and the final result.

RESULTS

The times required for the conversation were 7 minutes for scenario 1, 15 minutes for scenario 2, and 16 minutes for scenario 3. Scenarios 1 and 2 met the BRCA1/2 testing criteria, but scenario 3 did not, and this result was consistent with the findings of 3 experts who retrospectively reviewed conversations with the chatbot according to the 3 scenarios. A family history comparison ascertained by the chatbot with the actual scenarios revealed that each result was consistent with each scenario. From a genetic medicine perspective, no errors were noted by the 3 experts.

CONCLUSIONS

This study demonstrated that chatbot systems could be applied to preliminary genetic medicine screening for HBOC.
An Infection Model for severe COVID-19 (Preprint)
Authors: Ho P
Published: October 2020

UNSTRUCTURED

We wish to propose an infection model to address some of the unique and unusual features observed in COVID-19, eg. why were severe patients mounting more intense immune response compared to the mild cases, why did severe patients demonstrate higher and more protracted viral shedding when the immune response was greater, etc. In this exposition, we will first describe a generic acute viral infection framework based on work done mainly in influenza infection to understand the acute infective cycle, then contrast it with COVID-19 data to highlight main differences to construct a pathogenic model, and finally extrapolate to discuss applications in potential therapeutic considerations.
Универсальный высокоавтоматизированный лазерный технологический комплекс на базе многолучевого лазера
Authors: Чухланцев Д.О. , Умнов В.П. , Мальцев В.В. , Шипихин Д.А.
Published: October 2020

Представлен лазерный комплекс с шестилучевым электроразрядным лазером. Лазерная система разработана в компании «ТермоЛазер» и предназначена для технологических процессов лазерной обработки. Комплекс обладает системой управления мощностью каждого луча и их взаимного расположения в зоне обработки. Это позволяет использовать лазерную систему в широком диапазоне применений с высоким качеством выполнения лазерных операций (для резки, сварки, модификации поверхности деталей, наплавки).
О СОСТОЯНИИ МЕТРОЛОГИЧЕСКОГО ОБЕСПЕЧЕНИЯ ОЦЕНКИ СООТВЕТСТВИЯ И КАЧЕСТВА ПРОДУКЦИИ В ПРОЦЕССЕ ПРОИЗВОДСТВА
Authors: Пронякин В. , Комшин А.
Published: October 2020

Достижение высокого уровня, качества и конкурентоспособности отечественной продукции на мировом рынке недостижимо без квалифицированного метрологического обеспечения оценки соответствия продукции в процессе производства. В то же время
в промышленности отсутствует необходимое количество кадров специалистов-метрологов.
ЭПИДЕМИЯ COVID-19 И МАШИНОСТРОЕНИЕ: ОПЫТ КНР
Authors: Акимов А.
Published: October 2020

Рассмотрены меры стимулирования машиностроительных отраслей китайской экономики, направленные на противодействие спаду, обусловленному пандемией коронавируса COVID-19 и торможением вследствие этого мировой экономики.
ПРИМЕНЕНИЕ T-FLEX АНАЛИЗА ДЛЯ ОПРЕДЕЛЕНИЯ КОЭФФИЦИЕНТА ЗАПАСА ОБРАЗЦА ПЛА-ПЛАСТИКА НА РАСТЯЖЕНИЕ
Authors: Маренкова А. , Дикарева В. , Петров П. , Сопрыкин Б.
Published: October 2020

Рассмотрена возможность применения современных CAE-программ для прогнозирования способности образца из полимерного материала выдерживать нагрузки, превышающие расчетные. Сделана оценка возможности расчета с применением САЕ-системы коэффициента запаса образца ПЛА-пластика на этапе выбора формы образца для испытания на растяжение.
On Development of American-Chinese Trading Relations
Authors: Pogodin S. N. , Yagya T. S.
Published: October 2020

The article is devoted to the analysis of the of American-Chinese trading relations’ development at the present stage. The economic strategies of the USA and China towards each other in the period up to 2016 are investigated and the changes that have occurred in the positions and activities of the administration of these two states since 2017 are tracked. The statistical data reflecting the state of bilateral trade of the USA and China, their investment activities for the period up to 2016 and in the new period from 2017 are analyzed. The emphasis is on identifying new features of American-Chinese trade and investment cooperation during the D. Trump’s administration. Attention is paid to the motives of the trade conflict named the trade war between the USA and China, and its results.
Evaluación de la política pública sobre bioetanol como combustible en Perú, 2003-2019
Authors: Pacheco Canales Yanina Roxana
Published: October 2020

La política que el gobierno peruano utiliza para la promoción del bioetanol como combustible no ha logrado los resultados que se esperaban al momento de su diseño. En ese contexto, el objetivo de este artículo es evaluar la política energética. Con esa finalidad, se utilizan los aportes de los expertos en la materia para evaluar la eficacia de los instrumentos empleados y sus impactos. Luego, se analizan los elementos necesarios para replantear el diseño de la política. En consecuencia, se plantea la inclusión del objetivo de disminuir el calentamiento global y la creación de una entidad multisectorial como articuladora del mercado de biocombustibles, además de ajustes que conlleven una política pública con mejores beneficios para la sociedad.
Evolución y tendencias investigativas en marketing orientado a industrias culturales y creativas: un análisis bibliométrico en Scopus
Authors: Valencia Jackeline , Umba López Ana María , Moná Ana María , Valencia-Arias Alejandro , Patiño Vanegas Camilo
Published: October 2020

El objetivo de esta investigación es examinar la evolución y tendencias investigativas sobre marketing orientadas a industrias culturales y creativas. La metodología parte de un análisis bibliométrico de 374 documentos académicos obtenidos a partir de una ecuación de búsqueda formulada en Scopus, para esto se plantearon indicadores de cantidad, calidad y estructura. Entre los hallazgos, se observa que es necesario un mayor enfoque en economías emergentes, ya que su contexto social, cultural y económico es particular. Se concluye que los temas más investigados son: estrategia de mercado, diseño de producto, influencia del factor cultural, gestión de la industria (en términos de capacidades operativas y operacionalización) y acciones de internacionalización orientadas a la expansión de dichas industrias.
Mutaciones estatales y el complejo hidrocarburífero de formosa
Authors: Giuliano Ernesto Fabián
Published: October 2020

El presente trabajo analiza el proceso de mutación del Estado y la dinámica de políticas públicas productivistas fragmentarias que se van acoplando a las alteraciones, continuidades y reforzamientos acaecidos en el complejo hidrocarburífero de Formosa, Argentina en el marco de su inserción periférica intra-nacional y supranacional entre 1991-2012. Con una metodología que combina fuentes documentales con datos cuantitativos, se observa al Estado provincial mutando nuevas funciones económicas cuyo entramado resulta similar a lo que Jessop llama Estado workfarista. De este proceso se estudia cómo la dinámica de plegamiento de políticas públicas productivistas fragmentarias configuran un patrón regulativo escalar neoliberal en el complejo hidrocarburífero, lo que facilita la penetración del gran capital, el control y el manejo de activos como el petróleo y su explotación extractivista-exportadora. Esa lógica de acumulación hace emerger relaciones asimétricas de poder en lo político, económico y social. De modo que, el espacio económico-territorial en estudio se transforma con la continuidad de desigualdades persistentes.
ACEPÇÕES DO CONTEMPORÂNEO
Authors: Maia Francisco Jadson Silva , Almeida Luzia Cristina Lopes , Herculano Maia Lídia Raquel , Galeno Alexsandro
Published: October 2020

O presente trabalho expõe os desdobramentos da civilização da leveza, como cunha Gilles Lipovetsky (2016), o tipo atual de projeto civilizatório e suas representações em circuitos midiáticos, articulando especialmente questões referentes à produção, à cultura e ao trabalho. Leveza e liquidez assinalam conjuntamente a precariedade e a insegurança, mas também se contrariam, pois Lipovetsky (2016) e Zygmunt Bauman (2001) parecem divergir sobre a incursão do prazer frente ao trabalho e dos possíveis ganhos civilizatórios desse contexto. Em tempo, a emergência de um capitalismo criativo, transestético estabelece uma economia do leve que dá à cognição e à subjetividade papéis centrais na elaboração de produtos e serviços. Nesta perspectiva, as considerações de Lipovetsky (2016) e Byung-Chul Han (2015) atuam conjuntamente e oferecem uma análise que verifica o caráter esquivo e ambíguo das transformações técnicas atuais, apresentadas tanto nos objetos ultraleves quanto nas implicações de desempenho e de cansaço do trabalho na contemporaneidade. Com enfoque predominantemente teórico, esses aspectos relacionados à leveza e ao cansaço são aqui discutidos tendo como base a obra de Lipovetsky e o olhar para as representações desses fenômenos em espaços midiáticos hegemônicos, como a Veja SP.
Palavras-chave: Civilização da leveza. Cansaço. Trabalho. Lipovetsky.
A COMUNIDADE ARTESÃ DO ALTO DO MOURA NO SÉCULO 21
Authors: Sá Marcio , Souza Denise Clementino de , Sousa Jessica Rani Ferreira de , Leal Bárbara Tayná
Published: October 2020

Este trabalho teve como objetivo caracterizar as tensões disposicionais emergentes entre membros-proprietários(as) de negócios na comunidade artesã do Alto do Moura, Pernambuco, neste século 21. Nesse sentido, são recuperadas discussões acerca dos conceitos de território, urbanização e espaço social na literatura nacional e internacional, que permitiram situar as tensões emergentes na comunidade enquanto um espaço social local em transformação. Apoiando-se na noção de tensão disposicional (Bourdieu) como instrumento teórico e metodológico, a pesquisa foi norteada por uma abordagem epistêmica construtivista e utilizou como intrumentos para o trabalho de campo entrevistas semiestruturadas, notas de campo e grupos focais. As principais tensões disposicionais analisadas foram referentes às novas paisagens, vizinhanças e à insegurança comunitária, associadas aos conjuntos habitacionais mais recentes e a seus novos moradores, e à concorrência exacerbada e ao fator classe na aceitação social, relativos às mudanças no padrão de relacionamento comunitário.

Palavras-chave: Comunidade artesã. Alto do Moura. Espaço social local. Tensões disposicionais emergentes.
CATADORAS DE MATERIAIS RECICLÁVEIS E O CUIDADO EM SAÚDE
Authors: Vasconcelos Joaquim Pedro Ribeiro , Bruna Carvalho Barros Rosa Nobre  , Izabel Cristina Bruno Bacellar Zaneti  , Sílvia Maria Ferreira Guimarães
Published: October 2020

As trabalhadoras catadoras de materiais recicláveis são fundamentais na promoção de ações sustentáveis para a proteção do meio ambiente, apesar de viverem num cenário de precarização da vida. Diante disso, este artigo tem como objetivo compreender o contexto de vida e o cuidado em saúde dessas mulheres na lida cotidiana. Este estudo revela o universo dessas trabalhadoras informais organizadas em uma associação com sede em Ceilândia (DF). Foram realizadas entrevistas semiestruturadas com as catadoras, sendo complementada pela observação de suas atividades cotidianas no galpão de triagem de materiais recicláveis. Os achados apontam para questões marcantes relativas a: precariedade do trabalho na lógica da reestruturação produtiva do capital; opressões das mulheres na perspectiva interseccional de raça, gênero e classe; as dificuldades do acesso aos serviços oficiais de saúde. Especialmente, é discutido também as experiências relacionadas à assistência à saúde e à rede popular de compartilhamento do cuidado como forma de resistência.

Palavras-chave: Trabalho. Catadoras de materiais recicláveis. Sociabilidades. Saúde.
INVISIBILIDADES, INSURGÊNCIAS E EMERGÊNCIAS
Authors: Recoaro Deise , De Menezes Marilda Aparecida , Jard da Silva Sidney , Santos Júnior Jaime
Published: October 2020

Neste artigo, apresentamos os resultados parciais de uma pesquisa sobre as trajetórias de vida de mulheres que participaram do ciclo de greves históricas do ABC Paulista. Desse recorte mais amplo, fizemos uma incisão neste texto para trazer, na composição dos casos, as memórias de mulheres que assumiram cargos na estrutura sindical. Na hipótese de que os efeitos das formas de opressão que marcavam as trajetórias ocupacionais das mulheres na indústria metal-mecânica e nas montadoras do parque automotivo dessa região ecoavam nas estruturas sindicais, reproduzindo clivagens de gênero, importa-nos compreender as estratégias de resistência, as formas de engajamento na militância e os efeitos na ação sindical. As memórias deixam entrever o lento processo de reconhecimento das demandas de gênero, a perenidade das tensões relativas a essa clivagem nas estratégias de luta e as disputas discursivas por legitimidade das histórias das mulheres na narrativa sobre as greves do ABC Paulista.

Palavras-chave: Sindicalismo. Greves. Gênero. ABC Paulista.
SINDICALISMO, AUTORITARISMO E REPRESSÃO ENTRE DOIS POLOS
Authors: Marinho Maria Gabriela Silva Martins da Cunha , Meza Eliane Cristina de Carvalho Mendoza , Fonseca Karen Christina Dias da
Published: October 2020

O artigo analisa, em perspectiva histórica, aspectos da repressão desencadeada pelo acirramento político de 1968, com ênfase nas greves de Osasco e reverberações no ciclo posterior do ABC paulista no final da década de 1970. Constrói a análise a partir da produção memorialística de personagens do período a partir de um ângulo menos frequente, no caso, a perspectiva dos agentes do status quo e da repressão política. Nesse sentido, localiza a participação do Exército e de empresários que se destacaram, sobretudo, na conjuntura de 1968, um dos momentos mais agudos do fechamento político durante o regime militar. O argumento desenvolvido pressupõe a mudança de escala e natureza da repressão e seu deslocamento de forças marcadamente policiais para a vinculação ao escopo das “atribuições” das Forças Armadas, em particular do Exército. Desse modo, sindicatos e sindicalistas passaram a compor o espectro do “inimigo interno” definido na Doutrina de Segurança Nacional.  Um dos aspectos destacados é o caráter estratégico do setor metalúrgico sobre o qual a repressão incidiu pesadamente, segmento no qual muitas empresas estiveram associadas ao capital internacional.  Por outro lado, além de assinalar a especificidade da atuação militar na repressão sindical, o artigo procura agregar como elemento de análise a presença do empresariado na escalada repressiva.

 

Palavras-Chave: Autoritarismo e repressão. Ditadura Civil-Militar e sindicalismo. Memória de greves e acirramento político. São Paulo e o estado de exceção.
Diagnóstico molecular de SARS-CoV-2
Authors: Pinilla Gladys , Cruz B Claudia Andrea , Navarrete O Jeannette
Published: October 2020

El diagnóstico de COVID-19 se basa tanto en aspectos clínicos como en pruebas de detección, pero los síntomas y signos clínicos de los pacientes infectados son altamente atípicos y, por lo tanto, las pruebas moleculares son indispensables para su diagnóstico. La reacción en cadena de la polimerasa con transcriptasa inversa (RT-qPCR) se lleva a cabo en laboratorios nivel BSL II; asimismo, los principales blancos moleculares para la detección viral son el gen E (envoltura), y el gen RdRP (ARN polimerasa dependiente de ARN). Los falsos negativos en este diagnóstico se deben a la calidad y cantidad de la muestra, condiciones de transporte, almacenamiento, y manejo de estas antes y después de la extracción (el ARN es termolábil y abundantes las RNasas), fase de la infección, mutaciones del virus y presencia de inhibidores de la PCR. En estos casos, se recomienda una nueva toma de muestra, especialmente de vías respiratorias bajas, para aumentar la carga viral. Se debe tener en cuenta la sensibilidad analítica de la RT-qPCR (5,2 copias de ARN/reacción) y que, una vez el RNA se extrae, se va degradando progresivamente afectando la sensibilidad diagnóstica de la prueba. Un diagnóstico oportuno permite optimizar el manejo (aislamiento y tratamiento) y monitorización de los pacientes, así como la aplicación de medidas de prevención y control de la expansión, y la vigilancia epidemiológica de la enfermedad.
Educação infantil e políticas públicas no Brasil: visões e reflexões
Authors: Carneiro Maria Angela Barbato
Published: October 2020

The contemporary society has been through a vast number of changes that affect childhood education in the whole world, especially in Brazil. The absence of public politics that includes the education of children between zero and seven years, has been incipient. Currently, we are facing serious social problems and there is a necessity of reviewing those politics in order to avoid going against democracy, offering low quality education to the less fortunate layers of society. Therefore, the present article is not the result of a research but has its goal based on concept of politics to analyze historically the course of childhood education in Brazil, taking in consideration its challenges, and reflect which are the possible changes to be considered for the next decade.
Inclusão, educação superior e educação do/no campo: o PRONERA no contexto do capital
Authors: Maciel Carina Elisabeth , Piatti Celia Beatriz , Souza Gisele da Rocha
Published: October 2020

This article aims to analyze the National Education Program on Agrarian Reform - PRONERA - as a higher education program that aims at inclusion at this level of education, but that finds resistance in the characteristics of a system that does not allow everyone access to education. This program is identified as State policy that has been maintained for 21 years, through clashes, struggles and demands, in opposition to the logic of plastered rural education, and proposes an emancipating, decolonizing education. The research is of bibliographic and documentary nature and, to subsidize the analyzes made, we resort to authors who reflect on the land struggle and agrarian reform, Rural Education, Alternation Pedagogy, Higher Education, in order to dialogue with Mészaros and Demir on the structural crisis of capital and its implications for rural education, with a focus on PRONERA. It is concluded that the inclusion policies made possible the development of PRONERA, but they maintain the neoliberal logic as structuring of this Program that, having as mentor an ultra-neoliberal government, has its principles shaken by the lack of resources and the prioritization of a privatized and meritocratic.
Organização do acesso e permanência das pessoas com deficiência no ensino superior a partir da instauração do Programa Incluir
Authors: Lara Patricia Tanganelli , Sebastián-Heredero Eladio
Published: October 2020

The Incluir Program influenced institutional policies for the implementation of accessibility actions for people with disabilities in higher education, in all Brazilian states. With financial support from the MEC, Brazilian universities created and/or restructured diversity support units in Federal Institutions of Higher Education and State Institutions of Higher Education. Thus, the objective of this work is to analyze how the current situation is, from the productions of theses and master's thesis, since their publication, to understand how these Higher Education institutions have organized to support the entry and permanence of people with disabilities after this financial contribution and the publications of the inclusion public policies in Brazil. The methodological procedures of this research are qualitative and bibliographic in nature, using content analysis. The results of this investigated period revealed progress in the implementation of public policies, after 2005, with the creation of diversity support units and resources for the inclusion of young people and adults with disabilities, it was also possible to identify the need for teacher formation and for professionals working in these institutions to eliminate the attitudinal and communication barriers located in many higher education institutions.
Desafios e perspectivas do estudante com deficiência visual na educação superior: análise da produção científica
Authors: Costa José Aparecido da , Madruga Rosely dos Santos , Anache Alexandra Ayach , Sebastian-Heredero Eladio
Published: October 2020

The inclusion of students with visual impairments in higher education has still been challenging for managers and teachers to ensure academic success. Despite the investment initiatives by the government, but they are still insufficient in the face of the difficulties of access and permanence of these students. Therefore, the objective of this work is to analyze research on access and permanence with an emphasis on Specialized Educational Assistance for students with visual impairments in the productions of the Special Education Journal of the Federal University of Santa Maria (UFSM) in the period from 2014 to 2019. We used a quantitative-qualitative analysis of the nature of reviewing scientific production in the journal in question, for this we work with the indicators of disability, visual impairment, higher education, access, permanence, specialized educational assistance and their combinations. The search resulted in 519 articles, of which only 39 address inclusion in higher education. 14 were selected for analysis, dealing with visual impairment, higher education, inclusion and permanence. We conclude that the number of visually impaired students in Higher Education has increased by more than 50% (fifty percent), that there is a set of legislation that favors inclusion, but the conditions, whether of resources/technologies or teacher formation, do not yet appear for its effectiveness, according to research. Specialized educational assistance, guaranteed by law, is not yet perceived as materialized. Publications are relevant for the creation of new policies, actions and strategies for the permanence of students with disabilities in higher education and specialized educational assistance according to their specificities, but it still need further study.
Association of Maternal Prepregnancy Diabetes and Gestational Diabetes Mellitus With Congenital Anomalies of the Newborn
Authors: Wu Yuxiao , Liu Buyun , Sun Yangbo , Du Yang , Santillan Mark K. , Santillan Donna A. , Snetselaar Linda G. , Bao Wei
Published: October 2020

OBJECTIVE

To examine the association of maternal prepregnancy diabetes, gestational diabetes mellitus (GDM), and 12 subtypes of congenital anomalies of the newborn.

RESEARCH DESIGN AND METHODS

We included 29,211,974 live births with maternal age ranging from 18 to 49 years old documented in the National Vital Statistics System in the U.S. from 2011 to 2018. Information on prepregnancy diabetes, GDM, and congenital anomalies was retrieved from birth certificates. Log-binomial regression was used to estimate risk ratios (RRs) and 95% CIs for congenital anomalies overall and by subtypes.

RESULTS

Of the 29,211,974 live births, there were 90,061 infants who had congenital anomalies identified at birth. The adjusted RRs of congenital anomalies at birth were 2.44 (95% CI 2.33–2.55) for prepregnancy diabetes and 1.28 (95% CI 1.24–1.31) for GDM. The associations were generally consistent across subgroups by maternal age, race/ethnicity, prepregnancy obesity status, and infant sex. For specific subtypes of congenital anomalies, maternal prepregnancy diabetes or GDM was associated with an increased risk of most subtypes. For example, the adjusted RRs of cyanotic congenital heart disease were 4.61 (95% CI 4.28–4.96) for prepregnancy diabetes and 1.50 (95% CI 1.43–1.58) for GDM; the adjusted RRs of hypospadias were 1.88 (95% CI 1.67–2.12) for prepregnancy diabetes and 1.29 (95% CI 1.21–1.36) for GDM.

CONCLUSIONS

Prepregnancy diabetes and, to a lesser extent, GDM were associated with several subtypes of congenital anomalies of the newborn. These findings suggest potential benefits of preconception counseling in women with preexisting diabetes or at risk for GDM for the prevention of congenital anomalies.
Driving Safety in Adolescents and Young Adults With Type 1 Diabetes
Authors: Roberts Alissa J. , Moss Ashley , Malik Faisal Saleem , Taplin Craig , Pihoker Catherine , Hirsch Irl B. , Read Kendra , Yi-Frazier Joyce P
Published: October 2020

Adolescent and young adult (AYA) drivers are
at high risk for automobile accidents and fatalities (1–3).
Unintentional accidents were the leading cause of death in 2017 of individuals aged
15– 19 years in the United States (4). Factors that increase driving safety risk
associated with AYA drivers include lack of driving experience, developmental
factors such as poor executive function, and propensity for risk-taking
behaviors (5,6).
Furthermore, cognitive abilities such as self-control and emotional regulation
are continuing to develop through late adolescence and into young adulthood, making
AYA drivers particularly vulnerable to practicing unsafe driving behaviors (7). Brain development—in particular the
prefrontal cortex, which relates to impulse control—is known to continue well
into young adulthood, not reaching adult dimensions until the mid-20s (8,9).