bluuebunny/crossref_metadata_2025 huggingface dataset:
Green Extraction of Polyphenols via Deep Eutectic Solvents and Assisted Technologies from Agri-Food By-Products
Authors: Zhou Man , Fakayode Olugbenga Abiola , Li Haoxin
Published: September 2023

Polyphenols are the largest group of phytochemicals with important biological properties. Their presence in conveniently available low-cost sources, such as agri-food by-products, has gained considerable attention in their recovery and further exploitation. Retrieving polyphenols in a green and sustainable way is crucial. Recently, deep eutectic solvents (DESs) have been identified as a safe and environmentally benign medium capable of extracting polyphenols efficiently. This review encompasses the current knowledge and applications of DESs and assisted technologies to extract polyphenols from agri-food by-products. Particular attention has been paid to fundamental mechanisms and potential applications in the food, cosmetic, and pharmaceutical industries. In this way, DESs and DESs-assisted with advanced techniques offer promising opportunities to recover polyphenols from agri-food by-products efficiently, contributing to a circular and sustainable economy.
Zinc Oxide-Encapsulated Copper Nanowires for Stable Transparent Conductors
Authors: Wang Bo , Yu Shihui , Huang Liang
Published: September 2023

Cu nanowire (NW)-based transparent conductors are considered to be highly promising constituents of next-generation flexible transparent electronics. However, the fast oxidation of copper under ambient conditions hinders the use of Cu NWs. Herein, we demonstrate a low-cost and scalable approach for preparing a ZnO shell on the surface of Cu NWs under ambient conditions. The covered ZnO shells enhance the oxidative stability of Cu NWs. The optical and electrical properties of ZnO@Cu NWs remain similar to the original performance of the Cu NWs (for example, before encapsulating: 13.5 Ω/sq. at 84.3%, after encapsulating: 19.2 Ω/sq. at 86.7%), which indicates that encapsulation with a ZnO shell enables the preservation of the transparency and conductivity of Cu NW networks. More importantly, the ZnO@Cu NWs exhibit excellent stability in terms of long-term storage, hot/humid environments, and strong oxidizing atmosphere/solution.
Investigation of the Optical Nonlinearity for Au Plasmonic Nanoparticles Based on Ion Implantation
Authors: Chu Huiyuan , Wang Hongpei , Huang Yancheng , Dai Hao , Lv Menglu , Zhang Ziyang , Jiang Cheng
Published: September 2023

The Au ion implantation process has emerged as an effective and simple method to be utilized for the fabrication of opto-electronic materials and devices due to numerous fascinating features of Au nanoparticles such as surface plasmon resonance (SPR), large third-order nonlinearity and a fast response time. In this paper, we describe the fabrication of a novel Au nanoparticle saturable absorber (Au NP-SA) by embedding the Au NPs into a SiO2 thin film using the ion implantation process, which shows excellent saturable absorption features due to the localized surface plasmon resonance (LSPR) effect of Au NPs. A stable and high-quality pulsed laser with a repetition rate of 33.3 kHz and a single pulse energy of 11.7 nJ was successfully constructed with the Au NP-SA. Both the stable operation characteristic of the obtained Q-switched pulsed laser and the high repeatability of the fabrication process of the Au NP-SA were demonstrated. In addition, the simple feasibility and maturity of the ion implantation process allow for the plasmonic nanoparticles to be easily integrated into other types of opto-electronic materials and devices to further improve their performance, and shows immense potential for the production of wafer-level products.
Predictive Equation for Basal Metabolic Rate in Normal-Weight Chinese Adults
Authors: Wang Xiaojing , Mao Deqian , Xu Zechao , Wang Yongjun , Yang Xiaoguang , Zhuo Qin , Tian Ying , Huan Yuping , Li Yajie
Published: September 2023

This study aimed to develop a predictive equation for basal metabolic rate (BMR) in normal-weight Chinese adults and provide a reference for establishing the national recommended dietary energy intake. A new equation for BMR was derived from a sample of 516 normal-weight Chinese adults (men = 253, women = 263), and this sample was collected from two previous studies. Furthermore, the accuracy of this new equation and eight other previous predictive equations was reviewed. The agreement and reliability were compared in terms of bias, accuracy, the intraclass correlation coefficient, and Bland–Altman plots between predictive equations. In addition, the newly developed equation was further verified using a small independent sample, which contained 41 healthy Chinese adults (men = 21, women = 20). The measured BMR (mBMR) of all participants, measured using indirect calorimetry, was 1346.2 ± 358.0 kcal/d. Thirty participants were excluded based on Cook’s distance criteria (Cook’s distance of ≥0.008). Previous equations developed by Henry, Schofield, Harris–Benedict (H-B), Yang, and Hong overestimated the BMR of healthy Chinese adults. The present equation displayed the smallest average bias (0.2 kcal/d) between the mBMR and predicted basal metabolic rate (pBMR). The limits of agreement of the present equation from Bland–Altman plots were −514.3 kcal/d and 513.9 kcal/d, which is the most narrow and balanced limit of agreement. Moreover, in the verification of the testing database, the pBMR of the new equation was not significantly different from the mBMR, and the accuracy was 75.6%. Compared with pre-existing equations, the present equation is more applicable to the prediction of BMR in healthy Chinese adults. However, further studies are required to verify the accuracy of this new equation.
Differential Metabolites in Osteoarthritis: A Systematic Review and Meta-Analysis
Authors: Liao Zeqi , Han Xu , Wang Yuhe , Shi Jingru , Zhang Yuanyue , Zhao Hongyan , Zhang Lei , Jiang Miao , Liu Meijie
Published: September 2023

(1) Many studies have attempted to utilize metabolomic approaches to explore potential biomarkers for the early detection of osteoarthritis (OA), but consistent and high-level evidence is still lacking. In this study, we performed a systematic review and meta-analysis of differential small molecule metabolites between OA patients and healthy individuals to screen promising candidates from a large number of samples with the aim of informing future prospective studies. (2) Methods: We searched the EMBASE, the Cochrane Library, PubMed, Web of Science, Wan Fang Data, VIP Date, and CNKI up to 11 August 2022, and selected relevant records based on inclusion criteria. The risk of bias was assessed using the Newcastle–Ottawa quality assessment scale. We performed qualitative synthesis by counting the frequencies of changing directions and conducted meta-analyses using the random effects model and the fixed-effects model to calculate the mean difference and 95% confidence interval. (3) Results: A total of 3798 records were identified and 13 studies with 495 participants were included. In the 13 studies, 132 kinds of small molecule differential metabolites were extracted, 58 increased, 57 decreased and 17 had direction conflicts. Among them, 37 metabolites appeared more than twice. The results of meta-analyses among four studies showed that three metabolites increased, and eight metabolites decreased compared to healthy controls (HC). (4) Conclusions: The main differential metabolites between OA and healthy subjects were amino acids (AAs) and their derivatives, including tryptophan, lysine, leucine, proline, phenylalanine, glutamine, dimethylglycine, citrulline, asparagine, acetylcarnitine and creatinine (muscle metabolic products), which could be potential biomarkers for predicting OA.
Plant Protein but Not Animal Protein Consumption Is Associated with Frailty through Plasma Metabolites
Authors: Tanaka Toshiko , Das Jayanta K. , Jin Yichen , Tian Qu , Moaddel Ruin , Moore Ann Zenobia , Tucker Katherine L. , Talegawkar Sameera A. , Ferrucci Luigi
Published: September 2023

There is evidence that the association of protein intake and frailty may depend on the source of dietary protein. The mechanism underlying this association is not clear. In this study, we explore circulating metabolites as mediators of the relationship between dietary protein and of frailty in participants of the Baltimore Longitudinal Study of Aging (BLSA). Cross-sectional analyses in 735 BLSA participants of associations between plant and animal protein intake and frailty. Usual protein intake from plant and animal sources were estimated with a Food Frequency Questionnaire (FFQ) and frailty was assessed with a 44-item Frailty Index (FI). Compared with the lowest quartile, higher quartiles of plant, but not animal, protein were associated with lower FI. Twenty-five plasma metabolites were associated with plant protein intake; of these, fifteen, including phosphatidylcholines, cholesterol esters, sphingomyelins, and indole metabolites, mediated the association between plant protein intake and FI. The protective association between plant protein consumption and FI is mediated by lower abundance of lipid metabolites and higher abundance of tryptophan-related metabolites.
Dietary Interventions in Ulcerative Colitis: A Systematic Review of the Evidence with Meta-Analysis
Authors: Herrador-López Marta , Martín-Masot Rafael , Navas-López Víctor Manuel
Published: September 2023

(1) Background: Ulcerative colitis (UC) is a chronic colon inflammation caused by genetic and environmental factors, including diet. This systematic review and meta-analysis aims to assess the impact of diet on UC management in children and adults (2) Methods: A comprehensive search across databases yielded relevant studies, and risk of bias in randomized controlled trials (RCTs) was assessed using the Cochrane Risk of Bias tool. This study was conducted in conformity to the 2020 PRISMA guidelines. The certainty of evidence for outcomes was evaluated using GRADE methodology. Meta-analysis was performed using Review Manager software version 5.4. (3) Results: Fourteen RCTs were included, results indicated higher clinical response, remission, and endoscopic remission rates in diet-treated groups. Carrageenan-free, anti-inflammatory, and cow milk protein elimination diets showed no significant advantages in maintaining clinical remission. However, a study involving fermented cow milk with bifidobacterial demonstrated favorable outcomes. Overall, pooled analysis leaned in favor of dietary intervention for sustaining clinical remission; (4) Conclusions: The relationship between diet and UC is an evolving terrain that demands deeper exploration. This systematic review and meta-analysis highlight the evolving relationship between diet and UC, necessitating further exploration. While understanding grows, adopting personalized dietary approaches could alleviate symptoms, and support a more positive disease trajectory.
Multitargeted Herbal Prescription So Shiho Tang: A Scoping Review on Biomarkers for the Evaluation of Therapeutic Effects
Authors: Tran Nguyen Khoi Song , Lee Ji Hwan , Lee Myong Jin , Park Jun Yeon , Kang Ki Sung
Published: September 2023

Alternative medicines, especially herbal remedies, have been employed to treat infections and metabolism-related chronic inflammation because their safety and multidimensional therapeutic potential outweigh those of synthetic drugs. So Shiho Tang (SSHT), a well-known Oriental prescription (Xiao Chai Hu Tang in Chinese) composed of seven herbs, is traditionally prescribed to treat various viral infections and chronic metabolic disorders in Asia with or without the support of other natural medicines. To provide a general background on how SSHT is used as a medicinal alternative, we conducted a scoping review using the PubMed database system. Among the 453 articles, 76 studies used aqueous extracts of SSHT alone. This result included seven clinical studies and 69 basic studies: cell-based, animal-based, and ex vivo studies. The in vitro and clinical reports mainly focus on hepatic infection and hepatocarcinoma, and the documentation of in vivo tests of SSHT presents a wide range of effects on cancer, fibrosis, inflammation, and several metabolic disorder symptoms. Additionally, among the seven clinical records, two reverse-effect case studies were reported in middle-aged patients. In brief, this systematic review provides general knowledge on the natural remedy SSHT and its potential in phytotherapeutic primary health care.
First-Row Transition 7-Oxo-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidine Metal Complexes: Antiparasitic Activity and Release Studies
Authors: Martín-Montes Álvaro , Jimenez-Falcao Sandra , Gómez-Ruiz Santiago , Marín Clotilde , Mendez-Arriaga José M.
Published: September 2023

Leishmaniasis and Chagas disease are still considered neglected illnesses due to the lack of investment in research, despite the fact that almost one million new cases are reported every year. Four 7-oxo-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidine (HftpO) first-row transition complexes (Cu, Co, Ni, Zn) have been studied for the first time in vitro against five different species of Leishmania spp. (L. infantum, L. braziliensis, L. donovani, L. peruviana and L. mexicana) as well as Trypanosoma cruzi, showing higher efficacy than the reference commercial drugs. UV and luminescence properties were also evaluated. As a proof of concept, anchoring of a model high-effective-metal complex as an antiparasitic agent on silica nanoparticles was carried out for the first time, and drug-release behaviour was evaluated, assessing this new approach for drug vehiculation.
Development and Bioactivity of Zinc Sulfate Cross-Linked Polysaccharide Delivery System of Dexamethasone Phosphate
Authors: Dubashynskaya Natallia V. , Bokatyi Anton N. , Trulioff Andrey S. , Rubinstein Artem A. , Kudryavtsev Igor V. , Skorik Yury A.
Published: September 2023

Improving the biopharmaceutical properties of glucocorticoids (increasing local bioavailability and reducing systemic toxicity) is an important challenge. The aim of this study was to develop a dexamethasone phosphate (DexP) delivery system based on hyaluronic acid (HA) and a water-soluble cationic chitosan derivative, diethylaminoethyl chitosan (DEAECS). The DexP delivery system was a polyelectrolyte complex (PEC) resulting from interpolymer interactions between the HA polyanion and the DEAECS polycation with simultaneous incorporation of zinc ions as a cross-linking agent into the complex. The developed PECs had a hydrodynamic diameter of 244 nm and a ζ-potential of +24.4 mV; the encapsulation efficiency and DexP content were 75.6% and 45.4 μg/mg, respectively. The designed DexP delivery systems were characterized by both excellent mucoadhesion and prolonged drug release (approximately 70% of DexP was released within 10 h). In vitro experiments showed that encapsulation of DexP in polysaccharide nanocarriers did not reduce its anti-inflammatory activity compared to free DexP.
Superluminescent Diodes Based on Chirped InGaAs/GaAs Quantum Well-Dot Layers
Authors: Maximov Mikhail V. , Gordeev Nikita Yu. , Shernyakov Yuri M. , Kornyshov Grigoriy O. , Beckman Artem A. , Payusov Alexey S. , Mintairov Sergey A. , Kalyuzhnyy Nikolay A. , Kulagina Marina M. , Zhukov Alexey E.
Published: September 2023

We study the applicability of InGaAs/GaAs quantum well-dots (QWDs) for active regions of broadband superluminescent diodes (SLDs) emitting in the 950–1150 nm spectral range; 2 mm long SLDs with a bent section and an active region based on seven chirped QWD layers show emission spectra centered at 1030 nm with a full-width at half-maximum of 80 nm and an output power of 2 mW. In a 250 µm long SLD with a tilted stripe that has an increased output loss, the width of the emission spectra is 113 nm at 20 °C and 120 nm at 60 °C.
Inaugural Description of Extrafloral Nectaries in Sapindaceae: Structure, Diversity and Nectar Composition
Authors: Maximo Danielle , Ferreira Marcelo J. P. , Demarco Diego
Published: September 2023

Sapindales is a large order with a great diversity of nectaries; however, to date, there is no information about extrafloral nectaries (EFN) in Sapindaceae, except recent topological and morphological data, which indicate an unexpected structural novelty for the family. Therefore, the goal of this study was to describe the EFN in Sapindaceae for the first time and to investigate its structure and nectar composition. Shoots and young leaves of Urvillea ulmacea were fixed for structural analyses of the nectaries using light and scanning electron microscopy. For nectar composition investigation, GC-MS and HPLC were used, in addition to histochemical tests. Nectaries of Urvillea are circular and sunken, corresponding to ocelli. They are composed of a multiple-secretory epidermis located on a layer of transfer cells, vascularized by phloem and xylem. Nectar is composed of sucrose, fructose, xylitol and glucose, in addition to amino acids, lipids and phenolic compounds. Many ants were observed gathering nectar from young leaves. These EFNs have an unprecedented structure in the family and also differ from the floral nectaries of Sapindaceae, which are composed of secretory parenchyma and release nectar through stomata. The ants observed seem to protect the plant against herbivores, and in this way, the nectar increases the defence of vegetative organs synergistically with latex.
Analysis of Net Primary Productivity Variation and Quantitative Assessment of Driving Forces—A Case Study of the Yangtze River Basin
Authors: Liu Chenxi , Shi Shuo , Wang Tong , Gong Wei , Xu Lu , Shi Zixi , Du Jie , Qu Fangfang
Published: September 2023

Net primary productivity (NPP) can indirectly reflect vegetation’s capacity for CO2 fixation, but its spatiotemporal dynamics are subject to alterations to some extent due to the influences of climate change and human activities. In this study, NPP is used as an indicator to investigate vegetarian carbon ability changes in the vital ecosystems of the Yangtze River Basin (YRB) in China. We also explored the NPP responses to climate change and human activities. We conducted a comprehensive analysis of the temporal dynamics and spatial variations in NPP within the YRB ecosystems from 2003 to 2020. Furthermore, we employed residual analysis to quantitatively assess the contributions of climate factors and human activities to NPP changes. The research findings are as follows: (1) Over the 18-year period, the average NPP within the basin amounted to 543.95 gC/m2, displaying a noticeable fluctuating upward trend with a growth rate of approximately 3.1 gC/m2; (2) The areas exhibiting an increasing trend in NPP account for 82.55% of the total study area. Regions with relatively high stability in the basin covered 62.36% of the total area, while areas with low stability accounted for 2.22%, mainly situated in the Hengduan Mountains of the western Sichuan Plateau; (3) NPP improvement was jointly driven by human activities and climate change, with human activities contributing more significantly to NPP growth. Specifically, the contributions were 65.39% in total, with human activities contributing 59.28% and climate change contributing 40.01%. This study provides an objective assessment of the contributions of human activities and climate change to vegetation productivity, offering crucial insights for future ecosystem development and environmental planning.
Transcriptome Analysis Reveals Key Genes and Pathways Associated with the Regulation of Flowering Time in Cabbage (Brassica oleracea L. var. capitata)
Authors: Wang Jiao , Zhang Bin , Guo Huiling , Chen Li , Han Fengqing , Yan Chao , Yang Limei , Zhuang Mu , Lv Honghao , Wang Yong , Ji Jialei , Zhang Yangyong
Published: September 2023

Flowering time is an important agronomic trait in cabbage (Brassica oleracea L. var. capitata), but the molecular regulatory mechanism underlying flowering time regulation in cabbage remains unclear. In this study, transcriptome analysis was performed using two sets of cabbage materials: (1) the early-flowering inbred line C491 (P1) and late-flowering inbred line B602 (P2), (2) the early-flowering individuals F2-B and late-flowering individuals F2-NB from the F2 population. The analysis revealed 9508 differentially expressed genes (DEGs) common to both C491_VS_ B602 and F2-B_VS_F2-NB. The Kyoto Encyclopedia of Genes and Genomes (KEGGs) analysis showed that plant hormone signal transduction and the MAPK signaling pathway were mainly enriched in up-regulated genes, and ribosome and DNA replication were mainly enriched in down-regulated genes. We identified 321 homologues of Arabidopsis flowering time genes (Ft) in cabbage. Among them, 25 DEGs (11 up-regulated and 14 down-regulated genes) were detected in the two comparison groups, and 12 gene expression patterns closely corresponded with the different flowering times in the two sets of materials. Two genes encoding MADS-box proteins, Bo1g157450 (BoSEP2-1) and Bo5g152700 (BoSEP2-2), showed significantly reduced expression in the late-flowering parent B602 compared with the early-flowering parent C491 via qRT-PCR analysis, which was consistent with the RNA-seq data. Next, the expression levels of Bo1g157450 (BoSEP2-1) and Bo5g152700 (BoSEP2-2) were analyzed in two other groups of early-flowering and late-flowering inbred lines, which showed that their expression patterns were consistent with those in the parents. Sequence analysis revealed that three and one SNPs between B602 and C491 were identified in Bo1g157450 (BoSEP2-1) and Bo5g152700 (BoSEP2-2), respectively. Therefore, BoSEP2-1 and BoSEP2-2 were designated as candidates for flowering time regulation through a potential new regulatory pathway. These results provide new insights into the molecular mechanisms underlying flowering time regulation in cabbage.
The Effect of Different Rhizobial Symbionts on the Composition and Diversity of Rhizosphere Microorganisms of Chickpea in Different Soils
Authors: Zhang Junjie , Wang Nan , Li Shuo , Wang Jingqi , Feng Yufeng , Wang Entao , Li Youguo , Yang Tao , Chen Wenfeng
Published: September 2023

Background: Chickpea (Cicer arietinum L.) is currently the third most important legume crop in the world. It could form root nodules with its symbiotic rhizobia in soils and perform bio-nitrogen fixation. Mesorhizobium ciceri is a prevalent species in the world, except China, where Mesorhizobium muleiense is the main species associated with chickpea. There were significant differences in the competitive ability between M. ciceri and M. muleiense in sterilized and unsterilized soils collected from Xinjiang, China, where chickpea has been grown long term. In unsterilized soils, M. muleiense was more competitive than M. ciceri, while in sterilized soils, the opposite was the case. In addition, the competitive ability of M. ciceri in soils of new areas of chickpea cultivation was significantly higher than that of M. muleiense. It was speculated that there might be some biological factors in Xinjiang soils of China that could differentially affect the competitive nodulation of these two chickpea rhizobia. To address this question, we compared the composition and diversity of microorganisms in the rhizosphere of chickpea inoculated separately with the above two rhizobial species in soils from old and new chickpea-producing regions. Results: Chickpea rhizosphere microbial diversity and composition varied in different areas and were affected significantly due to rhizobial inoculation. In general, eight dominant phyla with 34 dominant genera and 10 dominant phyla with 47 dominant genera were detected in the rhizosphere of chickpea grown in soils of Xinjiang and of the new zones, respectively, with the inoculated rhizobia. Proteobacteria and Actinobacteria were dominant at the phylum level in the rhizosphere of all soils. Pseudomonas appeared significantly enriched after inoculation with M. muleiense in soils from Xinjiang, a phenomenon not found in the new areas of chickpea cultivation, demonstrating that Pseudomonas might be the key biological factor affecting the competitive colonization of M. muleiense and M. ciceri there. Conclusions: Different chickpea rhizobial inoculations of M. muleiense and M. ciceri affected the rhizosphere microbial composition in different sampling soils from different chickpea planting areas. Through high throughput sequencing and statistical analysis, it could be found that Pseudomonas might be the key microorganism influencing the competitive nodulation of different chickpea rhizobia in different soils, as it is the dominant non-rhizobia community in Xinjiang rhizosphere soils, but not in other areas.
Increasing Functionality of Fish Leather by Chemical Surface Modifications
Authors: Zilberfarb Achiad , Cohen Gali , Amir Elizabeth
Published: September 2023

Fish skin is a by-product of the fishing industry, which has become a significant environmental pollutant in recent years. Therefore, there is an emerging interest in developing novel technologies to utilize fish skin as a versatile raw material for the clothing and biomedical industries. Most research on finishing procedures is conducted on cattle leather, and practically very limited information on fish leather finishing is found in the literature. We have developed three functional surface finishing treatments on chromium (CL)- and vegetable (VL)- tanned salmon leather. These treatments include hydrophobic, oil repellent, and electro-conductive ones. The hydroxyl functional groups present on the surface of the leather were covalently grafted with bi-functional aliphatic small molecule, 10-undecenoylchloride (UC), by esterification reaction forming hydrophobic coating. The surface hydrophobicity was further increased via covalent binding of perfluorodecanethiol (PFDT) to the double bond end-groups of the UC-modified leather via thiol-ene click chemistry conditions. The oleophobic coating was successfully developed using synthesized fluorinated silica nanoparticles (FSN) and polyvinylidene fluoride-co-hexafluoropropylene (PVDF-HFP), showing oil repellency with a contact angle of about 100° for soybean oil and n-hexadecane. The electrically conductive coating was realized by the incorporation of conjugated polymer, polyaniline (PANI), via in situ polymerization method. The treated leather exhibited surface resistivity of about 5.2 (Log (Ω/square)), much lower than untreated leather with a resistivity of 11.4 (Log (Ω/square)).
Ce-radical Scavenger-Based Perfluorosulfonic Acid Aquivion® Membrane for Pressurised PEM Electrolysers
Authors: Siracusano Stefania , Giacobello Fausta , Tonella Stefano , Oldani Claudio , Aricò Antonino S.
Published: September 2023

A Ce-radical scavenger-based perfluorosulfonic acid (PFSA) Aquivion® membrane (C98 05S-RSP) was developed and assessed for polymer electrolyte membrane (PEM) electrolyser applications. The membrane, produced by Solvay Specialty Polymers, had an equivalent weight (EW) of 980 g/eq and a thickness of 50 μm to reduce ohmic losses at a high current density. The electrochemical properties and gas crossover through the membrane were evaluated upon the formation of a membrane-electrode assembly (MEA) in a range of temperatures between 30 and 90 °C and at various differential pressures (ambient, 10 and 20 bars). Bare extruded (E98 05S) and reinforced (R98 05S) PFSA Aquivion® membranes with similar EWs and thicknesses were assessed for comparison in terms of their performance, stability and hydrogen crossover under the same operating conditions. The method used for the membrane manufacturing significantly influenced the interfacial properties, with the electrodes affecting the polarisation resistance and H2 permeation in the oxygen stream, as well as the degradation rate, as observed in the durability studies.
A Concise Guide to Silicone-Based Spring-Roll Actuator Assembly
Authors: Ghazaryan Gagik , Khmelnitskaia Alina , Bezsudnov Igor , Kalinina Aleksandra , Agina Elena , Ponomarenko Sergey
Published: September 2023

A spring-roll actuator is a multilayer configuration of dielectric elastomer actuators that deforms in response to an electric field. To date, all spring-roll actuators are based on acrylate dielectric elastomers (DEs), and a few can reach deformations on a par with strains observed in natural muscles. Sensitivity to temperature and humidity, as well as the slow response times of acrylates, limit the commercialisation of these actuators. In this work, we developed a spring-roll actuator using commercial silicone DEs because they allow for a broader range of processing temperature and rapid response. Electrodes were deposited on a pre-strained DE film, coated with functional organosilicone polymer composite, and rolled around a metal spring. The coating enhanced the interfacial adhesion between DE and compliant electrodes, preserving the integrity and electro-mechanical properties of the fabricated spring-roll actuator. As to performance, the silicone-based spring-roll actuator could bear 200 times its own weight and displace it by 6% at the applied electric field of 90 V/μm.
Morphology Control of Electrospun Brominated Butyl Rubber Microfibrous Membrane
Authors: Zhu Tianxiao , Tian Ruizhi , Wu Liang , Zhang Dingyi , Chen Leying , Zhang Xianmei , Hao Xiangyang , Hu Ping
Published: September 2023

Brominated butyl rubber (BIIR) is a derivative of butyl rubber, with the advantage of high physical strength, good vibration damping performance, low permeability, aging resistance, weather resistance, etc. However, it is hard to avoid BIIR fiber sticking together due to serious swelling or merging, resulting in few studies on BIIR electrospinning. In this work, brominated butyl rubber membrane (mat) with BIIR microfiber has been prepared by electrospinning. The spinnability of elastomer BIIR has been explored. The factors influencing the morphology of BIIR microfiber membranes have been studied, including solvent, electrospinning parameters, concentration, and the rheological property of electrospinning solution. The optimal parameters for electrospinning BIIR have been obtained. A BIIR membrane with the ideal microfiber morphology has been obtained, which can be peeled from aluminum foil on a collector easily without being broken. Anti-bacterial property, the electrical conductivity of these membranes, and the mechanical properties of these samples were studied. The optimized BIIR electrospinning solution is Bingham fluid. The results of these experiments show that a BIIR membrane can be used in the field of medical prevention, wearable electronics, electronic skin, and in other fields that require antibacterial functional polymer materials.
Recent Advances in UV-Cured Encapsulation for Stable and Durable Perovskite Solar Cell Devices
Authors: Cao Mengyu , Ji Wenxi , Chao Cong , Li Ji , Dai Fei , Fan Xianfeng
Published: September 2023

The stability and durability of perovskite solar cells (PSCs) are two main challenges retarding their industrial commercialization. The encapsulation of PSCs is a critical process that improves the stability of PSC devices for practical applications, and intrinsic stability improvement relies on materials optimization. Among all encapsulation materials, UV-curable resins are promising materials for PSC encapsulation due to their short curing time, low shrinkage, and good adhesion to various substrates. In this review, the requirements for PSC encapsulation materials and the advantages of UV-curable resins are firstly critically assessed based on a discussion of the PSC degradation mechanism. Recent advances in improving the encapsulation performance are reviewed from the perspectives of molecular modification, encapsulation materials, and corresponding architecture design while highlighting excellent representative works. Finally, the concluding remarks summarize promising research directions and remaining challenges for the use of UV-curable resins in encapsulation. Potential solutions to current challenges are proposed to inspire future work devoted to transitioning PSCs from the lab to practical application.
Thin-Film Composite Membrane with Porous Interlayer Composed of Dendritic Mesoporous Silica Nanoparticles for Enhanced Nanofiltration
Authors: Jiang Chi , Zhang Mengmeng , Hou Yingfei
Published: September 2023

Positively charged nanofiltration (NF) membranes show great potential in the fields of water treatment and resource recovery. However, this kind of NF membrane usually suffers from relatively low water permeance. Herein, a positively charged NF membrane with a porous interlayer is developed, where the interlayer is formed by assembling dendritic mesoporous silica nanoparticles (DMSNs) after the formation of a polyamide layer. This post-assembly strategy avoids the adverse effect of the interlayer on the formation of positively charged NF membranes. The porous DMSN interlayer provides abundant connected channels for water transport, thus endowing the NF membrane with enhanced water permeance. A series of DMSNs with different sizes was synthesized, and their influence on membrane formation and membrane performance was systematically investigated. The optimized membrane exhibits a CaCl2 rejection rate of 95.2% and a water flux of 133.6 L·h−1·m−2, which is 1.6 times that of the control group without an interlayer. This work represents an approach to the fabrication of a positively charged NF membrane with porous interlayers for high-efficiency cation rejection.
Predictive Methodology for Quality Assessment in Injection Molding Comparing Linear Regression and Neural Networks
Authors: Fernández Angel , Clavería Isabel , Pina Carmelo , Elduque Daniel
Published: September 2023

The use of recycled polypropylene in industry to reduce environmental impact is increasing. Design for manufacturing and process simulation is a key stage in the development of plastic parts. Traditionally, a trial-and-error methodology is followed to eliminate uncertainties regarding geometry and process. A new proposal is presented, combining simulation with the design of experiments and creating prediction models for seven different process and part quality output features. These models are used to optimize the design without developing additional time-consuming simulations. The study aims to compare the precision and correlation of these models. The methods used are linear regression and artificial neural network (ANN) fitting. A wide range of eight injection parameters and geometry variations are used as inputs. The predictability of nonlinear behavior and compensatory effects due to the complex relationships between this wide set of parameter combinations is analyzed further in the state of the art. Results show that only Back Propagation Neural Networks (BPNN) are suitable for correlating all quality features in a single formula. The use of prediction models accelerates the optimization of part design, applying multiple criteria to support decision-making. The methodology is applied to the design of a plastic support for induction hobs. Furthermore, this methodology has demonstrated that a weight reduction of 27% is feasible. However, it is necessary to combine process parameters that differ from the standard ones with a non-uniform thickness distribution so that the remaining injection parameters, material properties, and dimensions fall within tolerances.
Preparation and Performance of Silicone Rubber Composites Modified by Polyurethane
Authors: Gao Lijun , Li Ying , Fu Wensheng , Zhou Liming , Fang Shaoming
Published: September 2023

Silicone rubber composites with good comprehensive properties modified with polyurethane were obtained through mixing and vulcanizing methods. Firstly, the polyurethane prepolymer with double bonds was prepared by polytetrahydrofuran glycol (PTMG, Mn = 1000), isophorone diisocyanate (IPDI), and 2-hydroxyethyl methacrylate (HEMA). The prepolymer was then added to the silicone rubber compounds to prepare silicone rubber composites, combining the excellent properties of polyurethane with the silicone rubber materials. The effects of polyurethane content on the mechanical properties, insulation, hydrophobicity, thermal stability, and flame retardancy of composites were studied in detail. The results showed that the silicone rubber composites not only have good hydrophobicity, thermal stability and flame retardant properties, but the addition of polyurethane significantly improves the tensile strength at room and low temperatures and the volume resistivity of the materials. The tensile strength increased by 32.5%, and the volume resistivity nearly doubled. The excellent electrical insulation, high hydrophobicity and good mechanical properties make the silicone rubber composites appropriate for use in the field of polymeric house arresters.
Utilizing Novel Lignocellulosic Material from Hart’s-Tongue Fern (Asplenium scolopendrium) Leaves for Crystal Violet Adsorption: Characterization, Application, and Optimization
Authors: Mosoarca Giannin , Vancea Cosmin , Popa Simona , Dan Mircea , Boran Sorina
Published: September 2023

In this work, a new lignocellulosic adsorbent was obtained and tested for crystal violet dye removal from water. The material was obtained from hart’s-tongue fern (Asplenium scolopendrium) leaves after minimal processing, without chemical or thermal treatment. The surface of the material was characterized using a variety of techniques, including FTIR, SEM, and color analysis. The effect of various factors on the adsorption capacity was then investigated and discussed. The kinetic and equilibrium studies showed that the general-order kinetic model and the Sips isotherm are the most suitable to describe the adsorption process. The equilibrium time was reached after 20 min and the maximum calculated value of the adsorption capacity was 224.2 (mg g−1). The determined values for the thermodynamic parameters indicated physical adsorption as the main mechanism involved in the process. The Taguchi method was used to optimize the adsorption conditions and identify the most influential controllable factor, which was pH. ANOVA (general linear model) was used to calculate the percentage contribution of each controllable factor to dye removal efficiency. Analysis of all the results shows that hart’s-tongue fern (Asplenium scolopendrium) leaves are a very inexpensive, readily available, and effective adsorbent for removing crystal violet dye from aqueous solutions.
Effectiveness of Different Application Modalities on the Bond Performance of Four Polymeric Adhesive Systems to Dentin
Authors: Bourgi Rim , Hardan Louis , Cuevas-Suárez Carlos Enrique , Devoto Walter , Kassis Cynthia , Kharma Khalil , Harouny Ryan , Ashi Tarek , Mancino Davide , Kharouf Naji , Haikel Youssef
Published: September 2023

One of the major goals of adhesive dentistry is to improve the interaction of the already-existing adhesives with different substrates by using different application techniques. Thus, the objective of the present in vitro study was to assess the bond performance of four adhesive systems, Prime&Bond Universal (PBU), Clearfil SE Bond (CSE), OptiBond Universal (OBU), and OptiBond FL (OBFL), to dentin using various application modes: passive application (PA), active application (AA), Compo-Vibes modified application (CVM), and Compo-Vibes application (CV). Eighty extracted human molars were allocated into four groups based on the application modalities tested. The micro-tensile bond strength as well as fracture mode were tested in accordance with ISO/TS 11.405 after 24 h and 6 months of aging. Adhesive contact angle (CA) and scanning electron microscope analysis were also performed (n = 3). Statistical tests were performed with α = 0.05. After 24 h, a significant difference with a higher bond strength value was found for PBU in the AA modality and for CSE in the CVM modality (p < 0.05). However, no significant difference was shown between the techniques used among the other adhesives (OBFL and OBU). Moreover, at 24 h, only the PA demonstrated significant differences between the tested materials (p < 0.05). After 6 months, CSE, PBU, and OBU demonstrated significant differences between the techniques (p < 0.05), with a higher bond strength for CSE in AA and CVM modalities, for PBU in AA modality, and for OBU in AA and PA modalities. No significant differences were found between the techniques used among the OBFL (p > 0.05). In addition, only the CVM technique demonstrated significant differences between the tested materials after 6 months. CV and CVM showed a decreased value after aging for CSE and PBU, respectively. However, all the modalities decreased for OBU and OBFL after aging. All the adhesives showed marked resin infiltration into dentinal tubules in AA among all the modalities tested. Both universal adhesive systems (OBU and PBU) demonstrated statistically lower CA when compared to the other systems (CSE and OBFL) (p < 0.05) when applied in the PA mode. Concerning the AA mode, only CSE and OBFL were tested. The AA demonstrated lower CA values compared to the same adhesives in PA (p < 0.05). It could be concluded that the bond strength could be influenced by both materials and application techniques. It seems that the AA technique could be recommended as a gold standard for the application of an adhesive system to dentin. Plus, the CV and CVM modalities after 6 months of aging were considered stable for PBU and CSE, respectively. Consequently, the performance of these adhesive systems might vary when applied to other modalities. Future studies are needed to test this hypothesis.
Anticancer Drug-Loaded Chitosan Nanoparticles for In Vitro Release, Promoting Antibacterial and Anticancer Activities
Authors: Ahmad Naushad , Khan Mohammad Rizwan , Palanisamy Subramanian , Mohandoss Sonaimuthu
Published: September 2023

Targeted drug delivery to tumor cells may be possible using nanoparticles containing human therapeutic drugs. The present study was carried out to develop cisplatin (CP) and 5-fluorouracil (FA) encapsulated chitosan nanoparticles (CSNPs), crosslinked with sodium tripolyphosphate (TPP) by an ionic gelation method and in vitro release, promoting antibacterial and anticancer activities. The prepared CSNPs, before and after CP and FA encapsulation, have been studied using various characterization techniques such as FTIR, XRD, SEM, and TEM-SAED patterning. The composites were well-dispersed, with an average particle size diameter of about 395.3 ± 14.3 nm, 126.7 ± 2.6 nm, and 82.5 ± 2.3 nm, respectively. In vitro release studies indicated a controlled and sustained release of CP and FA from the CSNPs, with the release amounts of 72.9 ± 3.6% and 94.8 ± 2.9%. The antimicrobial activity of the CSNPs-FA (91.37 ± 4.37% and 89.28 ± 3.19%) showed a significantly better effect against E. coli and S. aureus than that shown by the CSNPs-CP (63.41 ± 3.84% and 57.62 ± 4.28%). The HCT-116 cell lines were selected for in vitro cell cytotoxicity and live/dead assay to evaluate the preliminary anticancer efficacy of the CSNPs-CP and CSNPs-FA towards successfully inhibiting the growth of cancer cells.
Application of Filtering Techniques to Smooth a Surface of Hybrid Digital Bathymetric Model
Authors: Lubczonek Jacek , Zaniewicz Grzegorz
Published: September 2023

The aim of the research is to identify the optimal method for smoothing the surface of a hybrid digital bathymetric model (HDBM). The initiation of this research is justified by the fact that a model created from diverse types of data may have different surface textures and outliers. This diversity may cause problems in subsequent data processing stages, such as generating depth contours. As part of the adopted research methodology, fifteen filters were analysed. Filtering techniques were examined for filter type, the number of iterations, weights, and window size. The result is the adopted research methodology, which enabled the selection of the optimal filtering method. The research undertaken in this work is an extension of the methodology for developing an HDBM. An important aspect of the research is the approach to elaborating on such kinds of models in shallow and ultra-shallow waters adjacent to the land, as well as the use of data obtained by modern measurement platforms, such as unmanned surface vehicles (USV) and unmanned aerial vehicles (UAV). The studies fit into the general context of works related to the development of this type of model and undoubtedly provide a solid reference for further development or improvement of similar methods.
Advancements in Spaceborne Synthetic Aperture Radar Imaging with System-on-Chip Architecture and System Fault-Tolerant Technology
Authors: Xie Yu , Xie Yizhuang , Li Bingyi , Chen He
Published: September 2023

With the continuous development of satellite payload and system-on-chip (SoC) technology, spaceborne real-time synthetic aperture radar (SAR) imaging systems play a crucial role in various defense and civilian domains, including Earth remote sensing, military reconnaissance, disaster mitigation, and resource exploration. However, designing high-performance and high-reliability SAR imaging systems that operate in harsh environmental conditions while adhering to strict size, weight, and power consumption constraints remains a significant challenge. In this paper, we introduce a spaceborne SAR imaging chip based on a SoC architecture with system fault-tolerant technology. The fault-tolerant SAR SoC architecture has a CPU, interface subsystem, memory subsystem, data transit subsystem, and data processing subsystem. The data processing subsystem, which includes fast Fourier transform (FFT) modules, coordinated rotation digital computer (CORDIC) modules (for phase factor calculation), and complex multiplication modules, is the most critical component and can achieve various modes of SAR imaging. Through analyzing the computational requirements of various modes of SAR, we found that FFT accounted for over 50% of the total computational workload in SAR imaging processing, while the CORDIC modules for phase factor generation accounted for around 30%. Therefore, ensuring the fault tolerance of these two modules is crucial. To address this issue, we propose a word-length optimization redundancy (WLOR) method to make the fixed-point pipelined FFT processors in FFT modules fault tolerant. Additionally, we propose a fault-tolerant pipeline CORDIC architecture utilizing error correction code (ECC) and sum of squares (SOS) check. For other parts of the SoC architecture, we propose a generic partial triple modular redundancy (TMR) hardening method based on the HITS algorithm to improve fault tolerance. Finally, we developed a fully automated FPGA-based fault injection platform to test the design’s effectiveness by injecting errors at arbitrary locations. The simulation results demonstrate that the proposed methods significantly improved the chip’s fault tolerance, making the SAR imaging chip safer and more reliable. We also implemented a prototype measurement system with a chip-included board and demonstrated the proposed design’s performance on the Chinese Gaofen-3 strip-map continuous imaging system. The chip requires 9.2 s, 50.6 s, and 7.4 s for a strip-map with 16,384 × 16,384 granularity, multi-channel strip-map with 65,536 × 8192 granularity, and multi-channel scan mode with 32,768 × 4096 granularity, respectively, and the system hardware consumes 6.9 W of power to process the SAR raw data.