bluuebunny/crossref_metadata_2025 huggingface dataset:
Marine Microorganisms: New Frontier in Antimicrobial Therapeutics
Authors: Mandal Supratim
Published: March 2023

Emerging resistance to available antibiotics is one of the biggest problems of
mankind. This problem brings a serious question to the researcher’s mind: What will be
the next promising source of novel antimicrobial compounds to overcome drug
resistance? Although many synthetic or modified chemical compounds can be used as a
new source of the drug, nature is the richest and most versatile source of new
antibiotics. Natural products and their derivatives are far more important in the
discovery of new reliable sources of pharmaceuticals. We can use natural compounds
and their derivatives to treat cancer, diabetes, and inflammatory and infectious
diseases. Other reasons why natural compounds are a good choice for new drug
discovery are their lesser side effects, skill to control the existence and development of
diseases and potential to act against resistant strains of disease-forming
microorganisms. A huge number of diversified chemical components of marine
microorganisms, provide us with a rich and versatile source of biologically active
components. But among this enormous microbial diversity, very few amounts have
been explored till now. Marine microorganisms and their metabolites are reported as an
effective and promising sources of new antibiotics or drugs that can act against various
antibiotic-resistant strains of pathogenic microorganisms. Marine bacteria, fungi, and
cyanobacteria provide numerous industrially useful bioactive components which
further possess antibacterial, antifungal and antimycobacterial activities. There are
many biotechnological methods and machines like biosensors which is used to detect
and isolate useful target components from marine microorganisms. A slight
modification in the chemical groups of marine microbes-derive bioactive compounds
generates their new derivatives, mimetic and structural analogs that can serve as a
novel drug against pathogenic microorganisms. Every structurally different molecule
acts functionally with numerous biological activities against various pathogenic
microorganisms. This criterion makes marine-derived products more valuable to us in
this contemplative time of drug resistance. In this chapter, we discuss various
metabolites of marine microorganisms (bacteria, fungi, actinomycetes, and
cyanobacteria) having promising antimicrobial properties which could act as a potential
natural source of drugs against pathogenic microorganisms.
Advent of Pharmabiotics as a Promising Therapeutic Tool for Human Health and Diseases Management
Authors: Mulay Vanita , Satav Dhanashri , Fernandes Austin , Pisalwar Priyanka , Ahmed Shadab
Published: March 2023

With the recent advances in understanding the role of the gut microbiome
and human health, it has become evident that pharmabiotics have huge potential in the
therapeutics as well as supplement industries for conditions leading to impaired
microbiota. Pharmabiotics can be referred to as a class of microbial therapeutic
probiotics which could be live bacterial cells of human origin or their products with
clinically proven pharmacological activities found to be beneficial in human disease
conditions. So, the mechanism by which bacteria produce synergistic beneficial effects
on health could help us to develop a scheme to understand the delicate relationship
between the gut microbiome and human health. In this chapter, we will emphasize the
role of gut microbiota, the pharmabiotics they produce and how it affects different
physiological and metabolic and host-microbe interactions leading to the production of
bioactive chemicals with health benefits, eventually leading to the establishment of a
healthy immune system. The chapter will also discuss the repercussions of disturbed
gut microbiota on overall human health, including host psychiatric health. The fact that
pharmabiotics acting as antimicrobial agents will produce no resistant variety is also an
added bonus that increases the scope for discovery of such novel therapeutic agents.
Students’ readiness in following online learning during the Covid-19 pandemic
Authors: Wakijah Siti , Sukardi Thomas , Sudira Putu , Pramu Pramu , Iskandar Ranu , Haq Rijalul
Published: March 2023

The Covid-19 pandemic has impacted various sectors, including the education sector. This study aimed to determine Polbangtan YoMa students’ readiness to follow online learning during the Covid-19 pandemic. This research is survey research. The subjects of this study were 158 Polbangtan YoMa students. The instrument used for data collection was a questionnaire. Data were analyzed using descriptive statistics. This study results are: (1) the aspects of facilities and infrastructure get the percentage of 66%, meaning that Polbangtan YoMa students are ready to follow the learning from the aspect of  facilities and infrastructure; (2) the technological literacy aspect gets the percentage of 65%; meaning the Polbangtan YoMa students are ready to follow the learning from the aspect of their technological literacy abilities; (3) the quality aspect of online interactions gets the percentage 35%; meaning that Polbangtan YoMa students are not ready to take part in learning from the aspect of online interaction quality capabilities; (4) aspects of the benefits of online learning get the average sroce percentage of 52%, meaning that Polbangtan YoMa students agree that online learning will be helpful; (5) aspects of assistance services get the percentage of 67%, meaning that Polbangtan YoMa students entirely agree that assistance services help in online learning; and (6) aspects of online learning prospects get the average score percentage of 57%, meaning that Polbangtan YoMa students somewhat agree that online learning provides online learning prospects, thus Polbangtan YoMa students are ready to do online learning with an average proportion of 57%. The online learning model used at Polbangtan YoMa is asynchronous learning using e-learning, WhatsApp, and Google Classroom.
Effect of cloud computing on digital content skills and technology acceptance among secondary school students
Authors:   Curriculum and Instruction Department, Umm Al-Qura University, Mecca, Saudi Arabia, Alqarni Ali Suwayid , Al-Osaimi Ali Mutlaq ,   Curriculum and Instruction Department, Umm Al-Qura University, Mecca, Saudi Arabia
Published: March 2023

This paper aims to determine the impact of cloud computing digital content skills and technology acceptance among secondary school students. Using the quasi-experimental research design, the researchers succinctly measured the cloud computing effects on three variables: Cognitive achievement, digital content skills, and technology acceptance. A sample of 86 secondary school students in Jeddah was sampled using the cluster random sampling technique. The sample was divided into an experimental group and a control group; each group consisted of 43 students. Data were collected via a cognitive and performance test and a technology acceptance scale. Findings showed statistically significant differences between the mean scores of the experimental and control groups in the achievement test, the observation sheet, and the post-technology acceptance scale in favor of the experimental group (α=0.05). This indicates a positive impact of cloud computing on digital content skills and technology acceptance among secondary school students. Based on the findings, it is recommended to (a) effectively use cloud computing Apps and (b) replace the traditional paper-based method with technology to effectively store and work on available Apps embedded in cloud computing.
Contenidos digitales como herramienta de fortalecimiento para la escritura de textos descriptivos
Authors: Jiménez-Ordoñez Silvia Elena , Romero-Vergara Astrith Esther , Peñate Katia Ester
Published: March 2023

Objetivo. diseñar contenidos digitales como respuesta a las falencias en la producción escrita de textos descriptivos. Método. se trata de una investigación de campo, descriptiva, proyectiva en la que se usó la encuesta a 30 docentes y una prueba escrita sobre la comprensión y producción de textos descriptivos, aplicada a 21 estudiantes. Resultados. se evidencia que los estudiantes comprenden los textos descriptivos, pero que al momento de escribir no tienen las competencias para generar este tipo de textos. Para ello se propone una serie de contenidos digitales publicados en un blog de acceso abierto, que pueda ser usado en aula a fin de fortalecer la producción de textos descriptivos. Conclusiones. el desarrollo de competencias de escritura de textos descriptivos implica procesos tardíos que se compatibilizan con la naturaleza del desarrollo de la escritura; sin embargo, existen ejercicios adaptados al nivel de desempeño que contribuyen en la consolidación paulatina de las competencias.
ChatGPT in Clinical Toxicology
Authors: Sabry Abdel-Messih Mary , Kamel Boulos Maged N
Published: March 2023

ChatGPT has recently been shown to pass the United States Medical Licensing Examination (USMLE). We tested ChatGPT (Feb 13, 2023 release) using a typical clinical toxicology case of acute organophosphate poisoning. ChatGPT fared well in answering all of our queries regarding it.
Model for Achieving a Coordinated Access to Lung Cancer Care in Selected Public Health Facilities in KwaZulu-Natal, South Africa: Protocol for a Qualitative Study (Preprint)
Authors: Lubuzo Buhle , Hlongwana Khumbulani , Ginindza Themba
Published: March 2023

BACKGROUND

Timely delivery of high-quality cancer care to all patients is barely achieved in South Africa and many other low- and middle-income countries, mainly due to poor care coordination and access to care services. After health care visits, many patients leave facilities confused about their diagnosis, prognosis, options for treatment, and the next steps in their care continuum. They often find the health care system disempowering and inaccessible, thereby making access to health care services inequitable, with the resultant outcome of increased cancer mortality rates.

OBJECTIVE

The aim of this study is to propose a model for cancer care coordination interventions that can be used to guide and achieve coordinated access to lung cancer care in the selected public health care facilities in KwaZulu-Natal.

METHODS

This study will be conducted through a grounded theory design and an activity-based costing approach that will include health care providers, patients, and their caregivers. The study participants will be purposively selected, and a nonprobability sample will be selected based on characteristics, experiences of the health care providers, and the objectives of the study. With the study’s objectives in mind, communities in Durban and Pietermaritzburg were selected as study sites, for the study along with the 3 public health facilities that provide cancer diagnosis, treatment, and care in the province. The study involves a range of data collection techniques, namely, in-depth interviews, evidence synthesis reviews, and focus group discussions. A thematic and cost-benefit analysis will be used.

RESULTS

This study receives support from the Multinational Lung Cancer Control Program. The study obtained ethics approval and gatekeeper permission from the University’s Ethics Committee and the KwaZulu-Natal Provincial Department of Health, as it is being conducted in health facilities in KwaZulu-Natal province. As of January 2023, we had enrolled 50 participants, both health care providers and patients. Dissemination activities will involve community and stakeholder dissemination meetings, publications in peer-reviewed journals, and presentations at regional and international conferences.

CONCLUSIONS

This study will provide comprehensive data to inform and empower patients, professionals, policy architects, and related decision makers to manage and improve cancer care coordination. This unique intervention or model will address the multifactorial problem of cancer health disparities. If successful, this study will affect the design and implementation of coordination programs to promote optimal cancer care for underserved patients.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/34341
A Novel and Integrated Digitally Supported System of Care for Depression and Anxiety: Findings From an Open Trial (Preprint)
Authors: Wolitzky-Taylor Kate , LeBeau Richard , Arnaudova Inna , Barnes-Horowitz Nora , Gong-Guy Elizabeth , Fears Scott , Congdon Eliza , Freimer Nelson , Craske Michelle
Published: March 2023

BACKGROUND

The global burden of anxiety and depression has created an urgent need for scalable approaches to increase access to evidence-based mental health care. The Screening and Treatment for Anxiety and Depression (STAND) system of care was developed to meet this need through the use of internet-connected devices for assessment and provision of treatment. STAND triages to level of care (monitoring only, digital therapy with coaches, digital therapy assisted by clinicians in training, and clinical care) and then continuously monitors symptoms to adapt level of care. Triaging and adaptation are based on symptom severity and suicide risk scores obtained from computerized adaptive testing administered remotely.

OBJECTIVE

This article discusses how the STAND system of care improves upon current clinical paradigms, and presents preliminary data on feasibility, acceptability, and effectiveness of STAND in a sample of US-based university students.

METHODS

US-based university students were recruited and enrolled in an open trial of the STAND system of care. Participants were triaged based on initial symptom severity derived from a computerized adaptive test and monitored over 40 weeks on anxiety, depression, and suicide risk to inform treatment adaptation and evaluate preliminary effectiveness.

RESULTS

Nearly 5000 students were screened and 516 received care. Depression and anxiety severity scores improved across all tiers (P<.001 in all cases). Suicide risk severity improved in the highest tier (ie, clinical care; P<.001). Acceptability and feasibility were demonstrated.

CONCLUSIONS

STAND is a feasible and acceptable model of care that can reach large numbers of individuals. STAND showed preliminary effectiveness on all primary outcome measures. Current directions to improve STAND are described.
Đánh giá phương pháp tính toán lưu lượng nước mùa lũ tại trạm Vàm Nao
Authors: Phạm Thi Thu Hoa , Phạm Mỹ Hạnh
Published: March 2023

Dữ liệu lưu lượng nước thực đo tại các trạm quan trắc được sử dụng trong nhiều lĩnh vực như giao thông vận tải, thủy lợi và nông nghiệp. Tại vị trí sông Vàm Nao, nơi hợp lưu của sông Tiền và sông Hậu, cơ chế dòng chảy phức tạp, việc tính toán lưu lượng nước cần sự chính xác cao. Bài viết này dựa trên kết quả mô hình dòng chảy hai chiều được tính toán trên phần mềm Telemac 2D cho khu vực nghiên cứu từ trạm Châu Đốc và trạm Tân Châu xuống đến trạm Long Xuyên và trạm Chợ Mới. Mục tiêu chính của bài viết là đánh giá phương pháp tính toán lưu lượng nước mùa lũ tại trạm Vàm Nao. Dữ liệu lưu lượng nước thực đo mùa lũ tại trạm Vàm Nao năm 2017 được kiểm tra và đánh giá lại, từ đó có cơ sở để khẳng định rằng phương pháp tính toán lưu lượng mùa lũ tại trạm Vàm Nao cần được khắc phục và đề xuất phương pháp hợp lí để tính toán lưu lượng nước mùa lũ là nên dùng chế độ đo và phương pháp tính toán ở mùa kiệt tại trạm Vàm Nao.
Phân loại ảnh dựa vào hàm mật độ xác suất được trích xuất
Authors: Võ Văn Tài , Trần Nam Hưng , Huỳnh Văn Nhạng
Published: March 2023

Nghiên cứu nhằm đề xuất một thuật toán phân loại ảnh dựa vào hàm mật độ xác suất một chiều được trích xuất. Đầu tiên, dựa vào độ phân giải mức xám, mỗi ảnh được trích xuất thành một hàm mật độ xác suất một chiều đại diện và được chặt cụt trên đoạn Tiếp theo, xác suất tiên nghiệm của một ảnh cần phân loại được xác định dựa vào bài toán phân tích chùm mờ. Cuối cùng, một nguyên tắc phân loại cho ảnh được đề xuất. Ảnh được xếp vào một nhóm đã biết nếu nó có xác suất tiên nghiệm và sự tương tự  đến nhóm đó lớn nhất. Thuật toán đề nghị được minh hoạ từng bước và được áp dụng trên những tập ảnh cụ thể. Áp dụng đã cho kết quả tốt bởi vì nó có sai số thấp hơn nhiều phương pháp khác. Nghiên cứu này cũng cho thấy tiềm năng trong áp dụng thực tế của nhiều lĩnh vực liên quan đến nhận dạng ảnh.
Hiệu quả của dịch chiết bã hạt cây sở (Camellia oleifera) và tinh dầu cây dầu giun (Chenopodium ambrosioides L.), cây nghể răm (Polygonum hydropiper L.) trong phòng trừ rầy mềm (Aphis gossypii) gây hại cây chanh dây (Passiflora edulis)
Authors: Nguyễn Thị Liên , Trương Minh Ngọc , Đỗ Thị Mai Trinh , Hồ Thị Nguyệt , Lê Thị Huyền
Published: March 2023

Bài viết trình bày các kết quả thực nghiệm về hiệu lực phòng trừ rầy mềm của một số dịch chiết có nguồn gốc từ thảo mộc. Độc tính của cây sở (Camellia oleifera) (sử dụng phương pháp ethanol), cây dầu giun (Chenopodium ambrosioides L.) và cây nghể răm (Polygonum hydropiper L.) (sử dụng phương pháp nước) lên rầy mềm trong điều kiện phòng thí nghiệm và nhà màng đã được đánh giá, thông qua hiệu quả diệt rầy mềm của dịch chiết bã hạt cây sở ở nồng độ 20%  đạt hiệu quả tốt nhất (75,25% đối với rầy mềm sau 96 giờ phun), tinh dầu giun đạt hiệu quả tốt nhất (76,67% đối với rầy mềm ở nồng độ 0,20%) và tinh dầu nghể răm đạt hiệu quả tốt nhất (64,25 đối với rầy mềm ở nồng độ 0,25%). LC50 cuả tinh dầu giun, tinh dầu nghể răm, dịch chiết bã hạt sở lần lượt là 0,06%; 0,11%; 5,24 %. Hỗn hợp dịch chiết phối trộn nồng độ tinh dầu giun 0,4% và nồng độ dịch chiết bã hạt sở 20% đạt hiệu quả tốt nhất là 97,33% đối với rầy mềm ở 96 giờ sau khi xử lý. Hiệu lực tiêu diệt rầy mềm trên cây chanh dây của chế phẩm sinh học được đánh giá thông qua thực nghiệm trong điều kiện nhà màng, ở nồng độ 250 mL/L có hiệu quả cao trong việc phòng trừ rầy mềm.
Dấu ấn sông nước Đồng bằng sông Cửu Long trong sáng tác của Nguyễn Ngọc Tư
Authors: Nguyễn Thị Phương Nghi , Nguyễn Thị Hồng Hạnh
Published: March 2023

Sông nước Đồng bằng sông Cửu Long từ lâu được xem là tài sản vô giá và là nét đẹp đặc trưng cho vùng đất Nam Bộ của Việt Nam. Cảnh sông nước đã trở thành chất liệu cho sáng tác của nhiều nhà văn, trong đó có Nguyễn Ngọc Tư. Trong những trang văn của Nguyễn Ngọc Tư, sông nước Đồng bằng sông Cửu Long hiện lên hết sức sinh động và ấn tượng, vừa gần gũi, thân quen khi hiện diện trong từng nếp ăn, ở của người địa phương vừa nên thơ, mê hoặc như níu chân du khách. Đặc biệt, bên những dòng sông ấy còn hiện lên một thực trạng đáng báo động của một môi sinh đang bị hủy diệt. Sáng tác của Nguyễn Ngọc Tư đã cất lên tiếng nói phản tỉnh, kêu gọi việc nâng cao ý thức cùng những hành động thiết thực để bảo tồn những giá trị của tự nhiên nói chung và sông nước nói riêng.
What Characteristics are Important to Acute Care Health Professionals in Australia when Choosing a Palliative Care Prognostic Tool
Authors: Gaans Dr. Deborah van , Anastasi Ms. Lucy
Published: March 2023

Prognostic tools can aid acute care health professionals in the recognition of dying and identify when a patient should transition from active treatment to palliative care. The recognition of dying has important implications not only for the patient, but also for their family and others involved in providing care. Several prognostic tools are used in the Australian acute care setting, however they are not yet routine practice. Identifying what characteristics are important to acute care health professionals when choosing a palliative care prognostic tool may inform how the tools are presented and could increase their utilization by non-palliative care specialists. This survey found that the Supportive and Palliative Care Indicators Tool (SPICT) and Surprise Question are the most commonly known prognostic tools and are used in several clinical areas within the acute care setting. Acute care health professionals prefer validated prognostic tools which are easy to use, and are designed to be administered with the patient, substitute decision maker and the clinical team. The survey also identified the need for palliative care prognostic tools to be included within undergraduate teaching programs, further increasing the awareness and utilization of prognostic tools by health professionals working within the acute care setting.
SOCIAL INFLATION IN MTPL INSURANCE
Authors: Mecheski Stevcho , Joldeska Irina , Koseska Elena , Krstanoski Antonio , Naumoski Darko
Published: March 2023

The insurance industry is facing the negative effects of inflation in the post-pandemic period. In addition to economic inflation, the insurance industry also faces the phenomenon of social inflation, i.e. abnormal growth of claims caused by various social factors. In this paper, we examine whether insurance companies in the Balkans face social inflation. We analyze the growth rate of motor third-party liability insurance claims in 11 countries of the region for the period 2011-2020, including a more detailed analysis of the insurance market in the Republic of North Macedonia. The results show that there is no systematic existence of social inflation, but occasional abnormal shifts are noticeable for certain countries in the region, especially EU countries, i.e. certain companies in the Republic of North Macedonia. In addition, we find that social inflation occurs in countries with a higher rule of law index, indicating that low institutional development and low trust in institutions potentially prevent the development of social inflation. The paper contributes to the current literature by analyzing the problem in an international context and in a new region, as well as producing recommendations for policy makers.
Sistemas constructivos de la Ciudad Universitaria
Authors: Lazo Carlos
Published: March 2023

El arquitecto Carlos Lazo escribió un ameno texto en donde aborda los sistemas constructivos de la Ciudad Universitaria, repasando sus características y los principios bajo los cuales se rigieron tanto la elección del tipo de estructura, como de los materiales con los que se construyeron los diversos edificios del proyecto. Pone especial atención en la construcción del Estadio Olímpico, detallando momentos del proceso constructivo, desde la elección de una estructura de tierra, la solución lógica debido a la naturaleza del terreno. Lazo estuvo directamente involucrado en la ejecución del proyecto constructivo, por lo que este texto, escrito en 1952, ofrece una comprensión profunda de Ciudad Universitaria.
Mirando al minimalismo
Authors: Morales de Vega Luis Ángel
Published: March 2023

En el análisis de la relación entre el observador y las composiciones minimalistas, necesitamos estudiar diferentes acepciones del verbo mirar: la mirada de la élite, aparentemente cultivada; la mirada del pueblo ciego que necesita del kitsch; la mirada del inconsciente. Mirar y recorrer; mirar y comparar nuestro cuerpo con el entorno; mirar y desenfocar para completar lo borroso con nuestras emociones; mirar y construir tridimensionalmente; mirar y sentir con los cinco sentidos. La mirada háptica.
El paisaje es un punto más, una conversación con Manuel Mollá Ruiz-Gómez
Authors: Meza Aguilar María del Carmen
Published: March 2023

Entender el paisaje requiere de una vida completa de estudio con la mente abierta a toda manifestación del hombre sobre el medio, los lugares que transita, las expresiones culturales de los pueblos; todo ello visto con una mirada aguda y una amplia cultura que permita comprender y atar los cabos de lo visto para comprender el paisaje. Esta perspectiva privilegiada fue la característica del Dr. Manuel Mollá Ruiz-Gómez, a quien tuve la fortuna de conocer en 1990, en la primera de sus luego innumerables visitas a nuestro país, y quien falleció en 2019. Sirva pues esta entrevista realizada unas semanas antes de su fallecimiento, en una sobremesa vespertina, como un homenaje póstumo en agradecimiento a su magnífica aportación al estudio del paisaje.
Entrevista a Alberto González Pozo
Authors: Drago Elisa
Published: March 2023

El arquitecto Alberto González Pozo fue galardonado con la cátedra Extraordinaria Federico Mariscal, que cada año elige a profesionales de la arquitectura en México, para dictar una serie de 10 sesiones sobre su trayectoria personal y profesional. Además de las charlas, se presentó una exposición inaugurada en la galería Maria Luisa Dehesa Farías. Esta entrevista es parte de las actividades de esta cátedra, en la cual Elisa Drago platica con González Pozo repasando su trayectoria profesional y experiencias al trabajar con otros arquitectos como Abraham Zabludovsky, Enrique de la Mora, Fernando López Carmona, entre otros, abordando también su aprendizaje de viajes, sus primeros proyectos, así como su labor editorial y de difusión de la arquitectura.
Prevalence and Antibiotic Sensitivity Profile of Bacteria in Patients with Ear Infections
Authors: Al-Tulaibawi Nooralden Abdulkarem Jasim , Aal-Aaboda Munaf , Al-Qaesy Diana Basim Abdulhameed
Published: March 2023

Ear infections are extremely common and widespread otological disorders in children and adults. Accordingly, it is critical to identify the etiological factors and determine their antimicrobial susceptibility to achieve successful clinical outcomes. Ear swab samples were collected from patients aged 10-69 years at the Al-Sadar Teaching Hospital in Al-Amara city and cultured using the standard microbiological methods. The VITEK 2-compact system was used to analyze the bacterial isolates. A total of 100 samples were obtained; ear infection was slightly elevated in men (58%), but this was not significant. A significantly higher incidence of ear infection was observed in the patients aged 10–19 years (P≤ 0.05). Of the 100 examined ear swab samples, 76 yielded positive culture results, and of these, 61 were axenic and 15 were mixed. Among the 91 retrieved bacterial isolates, Pseudomonas aeruginosa (24/91, 26.3%) and Staphylococcus aureus (21/91, 23%) were the common causative agents of ear infection, while Haemophilus influenzae (2/91, 2.19%) and Staphylococcus hominis (1/91, 1.09%) were less common. Most bacterial isolates showed high sensitivity to imipenem and amikacin (87.9% and 79.1%, respectively; P≤ 0.01), followed by ciprofloxacin and gentamicin (67% and 60.4%, respectively; P≤ 0.05), and low sensitivity to amoxicillin/clavulanic acid and ampicillin (15.3% and 6.6%, respectively). Multidrug resistance was observed in most of the isolates.
juguetes electrónicos especializados y su influencia en el desarrollo cognitivo social y emocional de los niños entre 5 y 7 años
Authors: Jurado Pruna Francisco Xavier , Escobar Redín Erika Sofía , Albuja Mariño Patricia Alexandra , Albarracín Guarochico Wilmer Fabián
Published: March 2023

La etapa de la niñez constituye una época para el descubrimiento y la exploración en la que se desarrolla el aprendizaje de una forma natural, en este sentido los juegos son esenciales porque a través de estas actividades los niños conocen su entorno, desarrollan sus habilidades y aprenden a relacionarse, mientras que los juguetes les permiten enfrentarse a la realidad cuando son herramientas que facilitan la resolución de conflictos. Para el proyecto se empleó una metodología cualitativa, con alcance exploratorio y descriptivo, junto a una investigación previa que permitió establecer los parámetros de diseño de dos dispositivos electrónicos junto con sus estrategias didácticas, que tienen las características de ser juguetes que pueden ser utilizados como elementos para ayudar en la estimulación del pensamiento lógico en niños de entre cinco y siete años, los cuales facilitan el desarrollo de diversas habilidades, como la atención, la abstracción, la memoria, la representación, la simbolización y la resolución de problemas.
Impacts of Climate Change on Area and Production Under Different Crops in Bhandara District: Central India
Authors: Kapse Dr. Ganesh Motiram
Published: March 2023

Abstract: The present study Impacts of Climate Change on Area and production under different crops in Bhandara district, Central India. The hydrological parameters such as rainfall, drainage analysis, topographic parameters, and land-use patterns were evaluated and interpreted for district management of the area. This has been done using the sofware of the Arc map module in Arc GIS 9.3 and ERDAS Imagine 9.2 satellite image analysis. The hydrological investigation shows that the climate of the basin is characterized by hot summer from March to May followed by a rainy season from June to September. The postmonsoon season is also observed in the month of October. The annual mean rainfall range varies from 1,000 to 1,400 mm. The temperature rises rapidly from March to May. The monthly average maximum temperature rises to 47.50 Celsius in the month of May. In summer, the nights are cool compared to the scorching heat of the day. Bhandara district receives more rainfall than other districts of Maharashtra. The main crop here is paddy (rice). And 70% of agriculture is rain dependent. Total average rainfall for five years in seven districts of Bhandara district was recorded. Considering the total average rainfall in 5 years, Lakhandur taluka has the highest rainfall while Tumsar taluka has the lowest
Comparative Analysis of Legal Protection and Criteria of Well-Known Marks (Indonesia, United States, India, China, and Germany)
Authors: Winatha I Gede Mahatma Yogiswara , Prathama A.A.Gede Agung Indra , Kayuan Putu Chandra Kinandana
Published: March 2023

Trademark functions as a distinguishing mark between goods and/or services of its kind, as well as an identification mark for goods and/or services from the producer concerned. In order to be a well-known and widely recognized mark by the world community, and also to gain a good reputation it requires a very high investment to maintain quality and perform massive promotions in many countries. Considering this, lawful protection of well-known marks is a must. This research uses a normative juridical method by examining regulations and analyzing the previous studies, as well as other relevant legal materials to determine the criteria of well-known marks and the law protection provided for well-known marks in Indonesia. The results of this study indicate that the regulation of the criteria for well-known marks in Indonesia still does not set concretely the minimum number that must be met for each criterion. Furthermore, in principle, Indonesia provides legal protection for well-known marks, both registered and unregistered in Indonesia.
Analysis of Student Metacognitive Relationships with Problem Solving Abilities in Biology Learning
Authors: Yuni Astuti  , Izzah Nurul
Published: March 2023

Background: Problem Solving is one of the 21st century skills that must be mastered by students. In biology learning, the ability of students to solve problems using their metacognitive skills to process information and knowledge to solve problems. This study aims to describe the relationship between metacognitive skills and problem-solving abilities in biology learning in class XI science. Methods: method used in this research is descriptive correlation. The sampling technique used Cluster Random Sampling with  52 sample. The instrument used in this study was a questionnaire for metacognitive skills as many as 14 statement items with a Likert Scale and an essay test instrument for problem solving abilities as many as 6 questions. The data analysis technique was carried out with the help of the SPSS verse 24 program. Results:  of the hypothesis test showed that the value of the correlation coefficient R was 0.123 > 0.05 which means there is no relationship, in the regression equation Y' = 43.6 + 0.245X indicates that the relationship is positive. . In the analysis of variance (F test) the calculated F value was 0.771 with a Significant of 0.384 > 0.05 which means that it is not significant. Conclusions :it can be said that Ha is rejected and Ho is accepted, there is no significant relationship between students' metacognitive skills and problem solving abilities in learning biology. This can be due to the distance learning process that is applied to students related to the outbreak of the Covid-19 virus.
Aktivitas Ekstrak Daun Nangka (Artocarpus heterophyllus L.) Terhadap Bakteri Staphylococcus epidermidis
Authors: Sri Wahyu Vita  , Putri Vidiasari Darsono  , Saftia Aryzki
Published: March 2023

Background: Jerawat merupakan penyakit infeksi yang masih menjadi masalah serius. Terapi yang digunakan untuk jerawat adalah antibiotik bakteri Clindamycin. Namun masih banyak terjadi resistensi terhadap antibiotik tersebut, salah satunya Staphylococcus epidermidis, sehingga perlu dicari obat antibakteri alternatif untuk mengatasi jerawat. Terapi nonfarmakologi yang sering digunakan adalah ekstrak daun nangka (Artocarpus heterophyllus L.) yang mengandung metabolit sekunder seperti flavonoid, saponin, dan tanin yang diduga efektif sebagai antibakteri. Metode: Jenis penelitian yang digunakan adalah True Experimental dengan desain penelitian Posttest-Only Control Group. Metode penelitian menggunakan difusi sehat dan pengenceran cairan, kemudian data dianalisis menggunakan ANOVA. Hasil: Ditemukan bahwa ekstrak daun nangka (Artocarpus heterophyllus L.) memiliki aktivitas antibakteri terhadap Staphylococcus epidermidis dengan diameter zona hambat pada konsentrasi 50 ppm 11,7 mm, konsentrasi 75 ppm 12,1 mm, konsentrasi 100 ppm sebesar 12,3 mm dan memiliki daya hambat minimal pada konsentrasi 50 ppm dengan p-value 0,007 pada Kruskall-Wallis Test dan Mann Whitney Test menunjukkan p-value 0,025. Tetap saja, ekstrak itu tidak memiliki kemampuan membunuh minimum. Kesimpulan: Ekstrak daun nangka hanya dapat menghambat pertumbuhan bakteri Staphylococcus epidermidis tetapi tidak dapat membunuh pertumbuhan bakteri tersebut.
Studi Pengaruh Iradiasi Gamma Terhadap Kadar Senyawa Bioaktif dan Aktivitas Antiinflamasi Jahe Merah (Zingiber officinale roscoe)
Authors: Aulia Nova Kusumaningtyas  , Harahap Yahdiana , Mun'im Abdul , Supandi Supandi
Published: March 2023

Background: In Indonesia, the use of herbal plants in overcoming several health problems shows a fairly high rate. Red ginger is one of the herbs that is widely consumed and empirically has the property of relieving or reducing inflammation. However, as is well known, in general the microbiological contamination of herbs is quite high. To maintain the quality of herbal plants, special treatment is required, to ensure that microbial contamination is within safe limits. This study aims to determine the effect of gamma irradiation on the number of microbial contamination, and the bioactive content of 6,8,10-gingerol; 6-shogaol in 70% ethanol extract of red ginger, and its activity as an anti-inflammatory.

Methodes: Samples of 70% ethanol extract of red ginger were irradiated with various doses of 0, 5, 7.5, 10 and 15 KGy. Microbiological contamination is determined in Total Plate Number and Yeast Mold Number. The content of compounds 6,8,10-gingerol and 6-shogaol was observed by high performance liquid method and their anti-inflammatory activity was observed by protein denaturation inhibition (BSA) method. Results: Gamma irradiation at doses of 0, 5, 7.5, 10 and 15 KGy reduced microbial contamination as the exposure dose increased, and did not affect the levels of bioactive 6,8,10-gingerol; 6-shogaol and its anti-inflammatory activity. The anti-inflammatory activity of 70% ethanol extract of red ginger is influenced by the content of bioactive compounds.

Conclusion: Gamma irradiation is effective for decontaminating microbiological contaminants, and improving the quality of red ginger, and does not affect the bioactive levels contained and its anti-inflammatory activity (in vivo).

 

Keywords: 6,8,10-gingerol, 6-shogaol;  Anti-inflammatory ; Irradiation gamma rays; Zingiber officinale roscoe; Bovine serum albumin
Pelatihan Desain Observasi Kelas Berbasis Refleksi Diri
Authors: Fitriani Somariah , Syarif Moh. Suryadi , Muljono Hery
Published: March 2023

Background: Proses pengamatan kelas yang dilakukan para guru menjadi faktor penting dalam refleksi pengajaran berbasis penelitian dan pengembangan profesionalisme guru. Oleh karena itu tujuan kegiatan pengabdian masyarakat ini adalah mencoba meningkatkan pengetahuan, perubahan sikap dan ketrampilan para guru dalam meneliti yang dikhususkan pada observasi kelas sebagai alat pengumpulan data. Metode: 33 Partisipan dalam pelatihan ini adalah para guru SD yang berlokasi di Jakarta dan Bekasi. Kegiatan workshop dilakukan selama tiga hari dari bulan Maret sampai Mei 2022 dimana masing-masing sesi berlangsung selama tiga setengah jam. Kegiatan dilakukan secara daring dengan mengunakan platform Zoom sesuai kesepakatan dengan partisipan. Metode pelaksanaan yang digunakan adalah metode ceramah, demonstrasi dan diskusi secara interaktif. Hasil: Hasil kegiatan menunjukkan kepuasaan peserta dalam mengikuti workshop dengan antusiasme mereka dalam bertanya dan mendiskusikan desain-desain penelitian yang bisa mereka lakukan di kelas. Selain itu, hasil evaluasi menunjukkan kebermanfaatan kegiatan ini yang berkontribusi secara praktis kepada praktek mengajar mereka yang berbasis pada penelitian. Kesimpulan: Kolaborasi antar guru dalam penelitian juga menjadi hal yang dianjurkan kami dalam meningkatkan ketrampilan mereka yang berdampak pada profesionalisme dan performa mereka sebagai guru pada penerapan kurikulum merdeka.
Pemberdayaan Masyarakat Melalui Revitalisasi Bumdes Berbasis Sosial Berkelanjutan
Authors: Susanto Sony , Sigit Winarto
Published: March 2023

Background: Sosial berkelanjutan (Social Sustainability) merupakan hal yang perlu menjadi perhatian dalam pengembangan desa hal tersebut mengacu pada tindakan yang mendukung pengembangan desa selaras dengan keperdulian terhadap lingkungan. Permasalahan mitra yang beberapa dusun alami yaitu kekeringan, dimana hal ini merupakan fokus utama yang perlu diselesaikan. Kegiatan dilaksanakan pada bulan Mei sampai Agustus 2022. Metode: Tim pengabdi melakukan Focus Grup Discussion (FGD), benchmarking dan edukasi pengelolaan air yang berkelanjutan. Hasil: Hasil program pengabdian yaitu revitalisasi peran kader BUMDES dan pengelolaan air, sehingga air bisa di distribusikan ke seluruh masyarakat. Rencana tindak lanjut dalam pengabdian masyarakat ini adalah melakukan monitoring evaluasi hasil tindak lanjut FGD dan benchmarking yang sudah dilakukan. Kesimpulan: Monitoring pengelolaaan air yang sustainable perlu dilakukan agar dapat terus berjalan dan dimanfaatkan oleh masyarakat.
Гүний Хоолойн газар доорхи усны ашиглалтын нөлөө
Authors: Д.Алтантунгалаг  , П.Ууганбаяр  , С.Отгонбаатар
Published: March 2023

Comparative methods and the last decade of daily data were used estimate the relationship between precipitation and groundwater level response, and to analyze the consumption influence on confined aquifers in Gunii khooloi groundwater deposit, Umnugovi province, Mongolia.We have synthesized all the available data derived from the monitoring studies as well as carried out field measurements in this study. As a result of the monitoring study, water level of confined aquifer has been decreasing since 2011 related to the water consumption. There is a small depression cone in the eastern part of the area. According to the water level contour of 2013, groundwater level in confined aquifer near to the pumping well in the central part has been fluctuated and decreased about 10m. But it is observed that water level fluctuation is relatively stabilized from the 2015.
“Гуулин улсын судар”-ын тухай
Authors: B. Ariunbaigali
Published: March 2023

History of Goryeo Dynasty is one of the official histories of Korea and included Goryeo Dynasty’s politic, economy, social culture and biography of public figures which is most important fundamental source for our current studying the ancient history of that time. Therefore, many research studies has been made on the History of Goryeo Dynasty in perspective of manuscript study, literature study and culture study in apart from of history, at present in Korea. This source is written right after establishment of Joseon Dynasty as chronicle of the Goryeo Dynasty’s late period, whereas Korean scholars cannot eject view that political justification view point reflected on establishment of Joseon Dynasty.

However, the Goryeo Dynasty’s all time king’s Joseon wangjo sillok (실록. 實錄Veritable Records of the Joseon Dynasty) was used as the main source of creating the History of Goryeo Dynasty and the people present at that time such as “Comprehensive records arranged by year (편년통록. 編年通錄)” by Kim Kwan-ui (김관의. 金寬毅), “Comprehensive records of Gangmo (편년강목. 編年綱目)” by Min Ji (민지. 閔漬), “Records of reflection from Mirror (금경록. 金鏡錄)” by Yi Saek (이색. 李穡)and Yi Yinbok (이인복. 李仁復), “Sikmok pyeonsurok (식목편수록. 拭目編修錄)” and “Prescribed Ritual Text of the Past and Present (고금상정례. 古今詳定禮)” by Choe Yun-ui(최윤의. 崔允儀), “Ikjae-nango(익재난고. 益齋亂藁)” and “Scribbles of Old Man Oak (역옹패설. 櫟翁稗說)” by Yi Jehyeon (이제현. 李齊賢), and “Jugwanyukik (주관육익. 周官六翼)” by Kim, Goo-Yong(김구용. 金九容) are used as reference. Thus, researchers conclude that it describe assure true history of that period and one can say it elevate the value of the source.
Мигель Де Сервантес Сааведра ба монгол уншигчид
Authors: D. Galbaatar , G. Galbayar
Published: March 2023

Miguel de Cervantes is one of the world's pre-eminent novelists and the most celebrated figure in Spanish Renaissance literature. His life corresponds to the blend of high adventure and grim reality that shaped his masterpiece. His works have served as an illuminating mirror for each age that pick it up.

His most renowned work is “Don Quixote”, regarded as a world’s classic literature. The value of any literary creation is in its artistry. Artistically, the tradition and development of the novel, as well as its central concerns of human psychology and social satire, the question of human identity, and the interplay of the artist between the real and the imagined, can all be traced directly to life of Cervantes. In our opinion, the picaresque adventures of the mad Quixote and his ‘impossible dream’ and victory of reason and fact over fancy and idealism exhort the readers which makes “Don Quixote” as a stimulating novel. 

“Don Quixote” has been translated, in full, into Mongolian in 1972 and it represented broadly in art and drama.
Запятая в монгольском предложении: случаи постановки
Authors: D. Suvdantsetseg
Published: March 2023

Өгүүлэлд монгол хэлээр эх бүтээх болон монгол хэлний цэг тэмдгийн дүрэмд заасан тасалбарыг түлхүү хэрэглэх зарим тохиолдлыг хэсэгчлэн тусгаж байгаа билээ. Цэг тэмдгийн хэрэглээ болон тасалбарын олон үүрэг өгүүлбэрийн өгүүлбэр зүйн бүтэц болон түүний өгүүлбэр зүйн шинж чанараар нөхцөлдөж буй  монголын уран зохиолын хэрэглэгдэхүүн, мөн орос хэл рүү орчуулсан эхийн хэрэглэгдэхүүнтэй зэрэгцүүлэн авч үзсэн болно. Сүүлчийнх нь төрөл бус хэлнүүдийн өгүүлбэр зүйн өвөрмөц шинж болон цэг тэмдгийн хэрэглээний онцлогийг илрүүлэх боломж олгож байна. Нийлмэл өгүүлбэрийг цэг тэмдгээр хэлбэржүүлэхэд тасалбарын оролцоог онцлон авч үзлээ. Монгол, буриад, алтай хэлнүүдийн өгүүлбэр зүйн асуудлыг судалсан  нэрт хэл шинжээчдийг даган зохиогч үйлийн нэг эзэнтэй, олон өгүүлэхүүнтэй ба үйлийн нэг эзэн-олон өгүүлэхүүнтэй хам бүтцийг цэг тэмдгийн үүднээс шинжлэхийг зорив. Энэ нь орос хэлтэй харьцуулахад монгол хэлний  энгийн нийлмэл өгүүлбэр болон угсарсан нийлмэл өгүүлбэрийн өвөрмөц шинж болон эдгээр өгүүлбэрт хэрэглэж байгаа тасалбарын олон үүргийг илрүүлэх боломж олгож байна.
Англи хэлний заах арга зүйн сургалтад “моос” буюу бүх нийтэд нээлттэй онлайн сургалтыг ашиглах нь - ”Shaping the way we teach, 2” сургалтын жишээн дээр
Authors: N. Khosbayar
Published: March 2023

Massive Open Online Courses are web-based courses which have a goal of following unlimited participation. Although it began in the 1980’s, it has become free for everyone in last couple of years. Today most major universities are offering courses and they are working as partners with Courseria, Edx or Udocity webs. These courses help EL teachers and students who want to improve their crafts and skills. However it has spread and developed, still there are some challenges for students who wants to accomplish the course.
Нэр томьёоны бодлого
Authors: A. Enkhtuya
Published: March 2023

This article illustrates modern tendency of terminology, concept on terminology policy as a part of language policy, terminology applications and products, terminology planning, international aspects of terminology work, different categories of organization and network as well as some units responsible for terminology affairs in Mongolia and the necessity of policy to provide the coherence of terminology-related affairs in Mongolia.
Хүмүүнлэгийн ухааны чиглэлийн мэргэжлийн англи хэлний тухайд (курс хичээлийн онцлог)
Authors: Дмитриевна Ребикова Любовь , Ts. Erdenechimeg , Ts. Tsetsegmaa
Published: March 2023

ОХУ-д мэргэжлийн англи хэлийг (бизнесийн англи хэл) харьцангуй богино хугацааны өмнөөс буюу 1970 оноос  тусгай курс хичээл болгон судалж эхэлсэн байна.  Гадаад улс орнуудтай харилцах ажил хэргийн хамтын ажиллагаа хурдацтай хөгжиж ирсэн 1990 -д онд мэргэжлийн англи хэлний эрэлт хэрэгцээ эрс нэмэгдсэн. “Деловой английский язык” нэршил нь англи хэл дээрх “Business English”, нэр томьёны орчуулга бөгөөд англи - орос толь бичигт ‘business’ үгийн хэд хэдэн салаа утгын орчуулгыг  толилуулсан байна.
Үндэсний онцлог бүхий үгийн орчуулгын тухайд (Д.Нацагдоржийн “Шувуун саарал” өгүүллэгийн англи орчуулгын жишээгээр
Authors: D. Jivaa
Published: March 2023

Translation of cultural words is an important issue due to cultural gap between the source and target languages, as well as they cannot be literally translated. Since cultural concepts carry local inference, they are challenging tasks to be completed by a translator. The translation of the short story “A swift-footed steed” by B.Damdin ensured the equivalent including an appropriate descriptive function. To avoid distorting the meaning of the source language, the translator did not use literal translation. However, he used techniques including paraphrase, explanation, transcription and descriptive translations conveniently. This translation can be practical for translators who are performing culture-specific concepts.
Гадаад хэл сурах үеийн алдаа, үүнд хандах багш суралцагчийн хандлага
Authors: D. Sainbilegt , M. Chamintsetseg
Published: March 2023

Foreign language education has been developing as an interdisciplinary field of linguistics, education, and psychology and many studies have been done, such as teachers’ and students’ perceptions towards teaching and learning activities, curriculum, teaching and learning materials as well as a teacher development. This study investigated teachers’ and learners’ attitudes towards error correction, including the necessity, frequency, timing, type, method, and delivering agent of error treatment. One hundred sixty adult foreign language students and 25 teachers in three departments at Humanities Division, School of Arts and Sciences, National University of Mongolia participated in the surveys. The student participants’ proficiency levels varied from low intermediate to advanced.

The results revealed that both the teachers and students agreed that student errors should be treated, but students wanted more correction than their teachers thought. The teachers and students had significantly different opinions about timing, method, and delivering agents of error correction, as well as types of errors that need to be corrected.
Хятадын боловсролын систем дэх уламжлалт хятад судлалын нөлөө, чиг хандлага
Authors: L. Soyol , L. Solongo
Published: March 2023

The main purpose of an education system of any country is to make the citizens adapt moral behavior and ethics, at the same time offering basic knowledge of both natural and social science. Therefore, books and writings from the past play an inevitable role in making the above-mentioned objectives possible. We will discuss briefly about the impact of Chinese classical literature works to the field of Sinology and its future research tendency as they are the key subjects in learning about the history, culture, and tradition.