bluuebunny/crossref_metadata_2025 huggingface dataset:
BTB-autograft for mini open ACL replacement
Authors: Thomas Wolfram , Thomas Sascha , Walter Sebastian
Published: March 2016

Aims and Objectives:

This study intended to develop a new surgical approach combining easy operative handling as well as high functional outcomes for the reconstruction of the ACL.

Materials and Methods:

For the substitution of the ACL we use a Bone-tendon-bone auto-graft. After resecting the transplant from its original position and the mobilization of the Hoffa body the surgeon has an optimal sight onto the site of damage. During the whole intervention, the joint capsule is not resected.

Results:

In the time between September 2009 and January 2012 we treated 24 consecutive patients using this approach. Patients were evaluated using the Lysholm and the IKDC Score. Before the intervention patients scored 48, 6 ± 7, 4 resp. 43, 0 ± 4,8. After 36 months patients’score improved to 97, 1 ± 2, 6 resp. 96, 8 ± 2, 4; p = 0,037).

Conclusion:

Easy handling and precise placement of the graft demand the consideration of this technique as a standard treatment option.
Radiostereometric Evaluation of Tendon Elongation after Distal Biceps Repair
Authors: Marshall Nathan , Keller Robert A. , Guest John-Michael , Moutzouros Vasilios
Published: March 2016

Objectives:

Operative repair of distal biceps tendon ruptures have shown successful outcomes. However, little is known about the amount of tendon or repair site lengthening or creep. Treatment algorithms in regards to repair fixation, immobilization, initiation of activity and physical therapy are largely made on previous tendon healing principles and anecdotal findings. The purpose of our study was to evaluate distal biceps tendon repair via intratendinous radiostereometric analysis to evaluate tendon lengthening/creep at different time intervals of healing.

Methods:

Ten patients were recruited who sustained a distal biceps rupture requiring operative repair. Distal biceps repairs were performed using an endobutton only, single incision technique. Intraoperatively, two 2-mm tantalum beads with laser-etched holes were sutured to the distal biceps tendon. One bead was placed at the radius tendon interface and the other placed 1cm proximal to the first bead. Beads were evaluated via both CT scans immediately post-operatively and at 16 weeks and x-rays obtained at time 0 and then at 4, 8, and 16 weeks. Measurements were made using the endobutton to bead and bead-to-bead distances in order to assess repair site elongation as well as tendon elongation over time. Following final follow-up, patients underwent a DASH questionnaire and ultrasound to confirm the integrity of the tendon.

Results:

Ten patients were included in the study. Nine patients had complete ruptures with one having a partial rupture that underwent completion and subsequent repair. All patients showed statistically significant lengthening after surgery. The mean amount of lengthening after surgery was 21.8 mm (range 10.1-29.7 mm, p < 0.05). The repair site lengthened a mean of 12.5 mm (range 8.8-17.0 mm, p <0.05) and the tendon lengthened a mean of 9.4 mm (range: 4.0-18.8 mm, p<0.05) from surgery to final follow-up. The greatest change in lengthening was noted between time 0 and week 4 (mean: 11.8 mm, range: 4.0-18.0 mm, p<0.05), with the least amount of lengthening between week 8 and week 16 (mean: 3.6 mm, range: 2.1-5.5 mm, p<0.05). Average DASH scores after surgery was 4.5 (range: 2.5-16.7). Final ultrasound evaluations found no re-ruptures in any of the patients.

Conclusion:

This study’s findings suggest that all patients undergoing distal biceps tendon repair have significant elongation of their repair site and tendon after surgery, with the greatest amount of lengthening seen in the early post-operative period. These findings lend insight into decision-making with regards to intraoperative repair fixation and post-operative activity protocols while also adding knowledge to overall tendon repair principles.
Lacertus Fibrosis versus Achilles Allograft reconstruction for Chronic Distal Biceps Tears
Authors: Ramirez Miguel , Murthi Anand
Published: March 2016

Objectives:

Chronic distal biceps tears can be difficult to treat as in many cases, the remaining biceps tendon is significantly retracted and an allograft may be required to provide length for reconstruction. The lacertus fibrosis (LF), being a local, stout, fibrous sheath, can potentially be used as a reconstruction graft, obviating the need for allograft tissue. The purpose of this study is to evaluate the strength of the lacertus fibrosis compared to achilles allograft (AA) for distal biceps reconstruction.

Methods:

10 fresh-frozen matched cadaveric pairs of elbows were used in this study. The distal biceps tendon was isolated and 3 centimeters of tendon was resected. In Group 1, the LF was identified and released from its distal attachment, maintaining its attachment to the biceps muscle. This was then tubularized and repaired to the radius via button fixation. In Group 2, an AA tendon graft was sutured to the biceps muscle via Pulvertaft weave and similarly repaired to the ulna via button fixation. The prepared radii were rigidly mounted at a 45-degree angle in a MTS electromechanical test frame (MTS Systems, Eden Prairie, MN). The proximal biceps muscle was secured in a custom fabricated cryogenic grip and allowed to freeze for 60s prior to testing. Two differential variable reluctance transducers (DVRTs) were mounted on the specimens, one at the radius-soft tissue junction and the second in the muscle or muscle allograft tissue junction proximal to the repair. Specimens were then loaded at a displacement rate of 20 mm/min until failure. Failure was defined as a 3 mm displacement of the DVRT located at the radius-soft tissue junction. Stiffness was calculated from the initial linear portion of the load versus radial DVRT curve. A t-test was used to determine if any observed differences were significant (p≤0.05)

Results:

Load to failure, as defined as a 3mm gap formation by DVRT was similar between both groups. Load to failure in Group 1 (LF) was 20.17 ± 5.52 N versus 16.89 ±4.54 N in Group 2 (AA) (p=0.18). Stiffness of the construct was also not statistically different, with Group 1 (LF) averaging 12.32± 7.11 KPa versus 10.48 ± 5.66 KPa in Group 2 (AA) (p=0.34).

Conclusion:

Lacertus fibrosis reconstruction for chronic distal biceps tears was as strong biomechanically as the commonly used achilles tendon allograft in terms of load to failure and construct stiffness. This may be a reasonable alternative for chronic distal biceps reconstruction in which primary repair is not possible.
A transplant “immunome” screening platform defines a targetable epitope fingerprint of multiple myeloma
Authors: Schieferdecker Aneta , Oberle Anna , Thiele Benjamin , Hofmann Fabian , Göthel Markus , Miethe Sebastian , Hust Michael , Braig Friederike , Voigt Mareike , von Pein Ute-Marie , Koch-Nolte Friedrich , Haag Friedrich , Alawi Malik , Indenbirken Daniela , Grundhoff Adam , Bokemeyer Carsten , Bacher Ulrike , Kröger Nicolaus , Binder Mascha
Published: March 2016

Key Points

The myeloma transplant B-cell immunome is predictive for response to treatment. It may be exploited by immunosequencing and library technology as a source for unique target structures and antibodies for immunotherapy.
Biosafety of biotechnologically important microalgae: intrinsic suicide switch implementation in cyanobacterium Synechocystis sp. PCC 6803
Authors: Čelešnik Helena , Tanšek Anja , Tahirović Aneja , Vižintin Angelika , Mustar Jernej , Vidmar Vita , Dolinar Marko
Published: March 2016

In recent years, photosynthetic autotrophic cyanobacteria have attracted interest for biotechnological applications for sustainable production of valuable metabolites. Although biosafety issues can have a great impact on public acceptance of cyanobacterial biotechnology, biosafety of genetically modified cyanobacteria has remained largely unexplored. We set out to incorporate biocontainment systems in the model cyanobacterium Synechocystis sp. PCC 6803. Plasmid-encoded safeguards were constructed using the nonspecific nuclease NucA from Anabaena combined with different metal-ion inducible promoters. In this manner, conditional lethality was dependent on intracellular DNA degradation for regulated autokilling as well as preclusion of horizontal gene transfer. In cells carrying the suicide switch comprising the nucA gene fused to a variant of the copM promoter, efficient inducible autokilling was elicited. Parallel to nuclease-based safeguards, cyanobacterial toxin/antitoxin (TA) modules were examined in biosafety switches. Rewiring of Synechocystis TA pairs ssr1114/slr0664 and slr6101/slr6100 for conditional lethality using metal-ion responsive promoters resulted in reduced growth, rather than cell killing, suggesting cells could cope with elevated toxin levels. Overall, promoter properties and translation efficiency influenced the efficacy of biocontainment systems. Several metal-ion promoters were tested in the context of safeguards, and selected promoters, including a nrsB variant, were characterized by beta-galactosidase reporter assay.
Does the Technological Content of Government Demand Matter for Private R&D? Evidence from US States
Authors: Slavtchev Viktor , Wiederhold Simon
Published: March 2016

Governments purchase everything from airplanes to zucchini. This paper investigates the role of the technological content of government procurement in innovation. In a theoretical model, we first show that a shift in the composition of public purchases toward high-tech products translates into higher economy-wide returns to innovation, leading to an increase in the aggregate level of private R&D. Using unique data on federal procurement in US states and performing panel fixed-effects estimations, we find support for the model's prediction of a positive R&D effect of the technological content of government procurement. Instrumental-variable estimations suggest a causal interpretation of our findings. (JEL H57, H76, O31, O32, O38)
The Response of Tail Risk Perceptions to Unconventional Monetary Policy
Authors: Hattori Masazumi , Schrimpf Andreas , Sushko Vladyslav
Published: March 2016

We examine the impact of unconventional monetary policy (UMP) on stock market tail risk and risks of extreme interest rate movements. We find that UMP announcements substantially reduced option-implied equity market tail risks and interest rate risks. Most of the impact derives from forward guidance rather than asset purchase announcements. Communication about the future path of policy rates reduced volatility expectations of long-term rates and the associated risk premia. The reaction of equity market tail risk, in turn, points to the risk-taking channel of monetary policy, as the commitment to low funding rates may have relaxed financial intermediaries’ risk-bearing constraints. (JEL E52, E58, G12, G13, G14)
Concerning immune synapses: a spatiotemporal timeline
Authors: Ortega-Carrion Alvaro , Vicente-Manzanares Miguel
Published: March 2016

The term “immune synapse” was originally coined to highlight the similarities between the synaptic contacts between neurons in the central nervous system and the cognate, antigen-dependent interactions between T cells and antigen-presenting cells. Here, instead of offering a comprehensive molecular catalogue of molecules involved in the establishment, stabilization, function, and resolution of the immune synapse, we follow a spatiotemporal timeline that begins at the initiation of exploratory contacts between the T cell and the antigen-presenting cell and ends with the termination of the contact. We focus on specific aspects that distinguish synapses established by cytotoxic and T helper cells as well as unresolved issues and controversies regarding the formation of this intercellular structure.
THEORETICAL FOUNDATIONS OF THE STUDY OF THE PHENOMENON OF ELECTORAL CULTURE
Authors: Лыткина  , Lytkina Kseniya
Published: March 2016

The article explores theoretical foundations of the study of the phenomenon of electoral culture. Different interpretations of the concept are presented; the components that make up the structure of electoral culture are provided. The article describes features and the most common approaches to classify electoral culture, presents relationships between the concepts of «political culture» and «electoral culture». It is shown that the study of various aspects of electoral culture can be considered as a perspective direction of sociological research, which allows predicting the behavior of the subjects of the electoral process with a high degree of probability.
THE PROGRAM APPROACH OF TECHNICAL INFRASTRUCTURE OF CROP PRODUCTION OF THE OREL REGION
Authors: Докукина  , Dokukina Irina , Полянин  , Polyanin Andrey , Макарова  , Makarova Yuliya
Published: March 2016

In the article the theoretical bases of the program approach of the development of technical infrastructure are revealed. This direction is based on receiving a certain outcome in solving the problem. Target orientation involves setting the objectives for which the program actions are provided. Proposals on the development of the program in the form of a draft concept of additional regional program will be based on the indicative rates.
Self-Regulatory Institute of the Russian Financial Market and Prospects of Its Improvement
Authors: Смирнов  , Smirnov E.
Published: March 2016

The Federal Law of July 13, 2015 №223-FZ effective at the beginning of this year, provided all the necessary

conditions of a legal nature for the creation of effective self-regulation system in the Russian financial market.
Innovation, Financial Capacity of the Organization: Concepts Detaling
Authors: Подлепа  , Podlepa V.
Published: March 2016

The article discusses key issues of innovative development of the organizations associated with the concept and

definition of the capacity of the organization and its components.
Integrative Capabilities, Vertical Integration, and Innovation Over Successive Technology Lifecycles
Authors: Helfat Constance E. , Campo-Rembado Miguel A.
Published: March 2016

The analysis presented here provides a new explanation for why vertically integrated and specialized firms may continue to coexist as industries evolve, especially during time periods when conditions unequivocally favor lower cost specialized firms. In contrast to the common view that firms should match their organizational form to the prevailing nature of technology, vertically integrated firms may rationally choose to stay integrated and bear the sunk costs of developing integrative capabilities as well as the ongoing costs of maintaining them, even when they lose money during some time periods due to competition from lower cost specialized firms. In particular, in industries characterized by successive systemic innovations, which entail interdependence across stages of production, some firms may remain vertically integrated to maintain their capability to innovate over multiple cycles of technological innovation. The results hinge on the sunk costs of long-lived investments in integrative capabilities. An extension to the analysis suggests that vertically integrated firms may retain their organizational form to pioneer systemic innovations in other industries, including industries not subject to frequent technology lifecycles—providing another explanation of product-market diversification and market entry over time.
Drought tolerance selection of soybean lines generated from somatic embryogenesis using osmotic stress simulation of polyethylene glycol (PEG)
Authors: SUNARYO WIDI , WIDORETNO WAHYU , NURHASANAH NURHASANAH , SUDARSONO SUDARSONO
Published: March 2016

Abstract. Sunaryo W, Widoretno W, Nurhasanah, Sudarsono. 2016. Drought tolerance selection of soybean lines generated from somatic embryogenesis using osmotic stress simulation of polyethylene glycol (PEG). Nusantara Bioscience 8: 45-54. Somaclonal variation is an alternative source to create genetic variability including generating a novel character like drought tolerance. The objective of this research was to select the drought-tolerant lines derived from somatic embryogenesis (somaclones) of 4 soybean genotypes using drought stress simulated by Polyethylene Glycol (PEG). Soybean seeds (R1 generation) generated from 37 somaclones (R0 generation) were grown on semi-hydroponic system using Greenleaf as supporting medium. The seedlings were watered with half strength of liquid Murishage and Skoog nutrient. The PEG solution treatment of either 0% or 15% (PEG: w/v = -0.41 Mpa osmotic potential) was applied in the MS solution, from the seedlings of 14 days old until harvesting period. The vegetative growth, intensity of leaf firing, plant biomass, and drought sensitivity index variables were observed during the PEG application. The same procedure was applied to the seeds, propagated conventionally, from the same genotypes as controls. The results showed that somatic embryogenesis had altered the drought sensitivity of soybean genotypes under drought stress simulated by PEG. Interestingly, the different drought tolerance level was shown by the R1 plants. Some lines were increased and the other lines were decreased compared to the control genotypes. From a total of 185 R1 plants, 4 plants increased their tolerance against drought stress and grouped as tolerant genotype.
Individuals With Disabilities Who Have Diabetes: Do We Have Targeted Interventions?
Authors: Comer-HaGans DeLawnia , Austin Shamly , Ramamonjiarivelo Zo
Published: March 2016

According to 2010 data from the Centers for Disease Control and Prevention (CDC), diabetes is the seventh leading cause of death in the United States. It is assumed that various diabetes interventions are available to help individuals manage this chronic disease, but that is not the case. The literature is scant regarding interventions focused on people with disabilities who have diabetes. The purpose of this article is to review interventions specifically focused on people with disabilities who have diabetes and to discuss the effect of these interventions on this population.
From Nonissue to Healthcare Crisis: A Historical Review of Aging and Dying With an Intellectual and Developmental Disability
Authors: McGinley Jacqueline M.
Published: March 2016

Individuals with intellectual and developmental disabilities are living unprecedentedly longer lives primarily due to the long-term benefits of the deinstitutionalization movement and widespread improvements in health outcomes. However, the consequences of this protracted aging process are significant, complex, and often poor not only for the individuals and their caregivers but for the mainstream healthcare community. This article will explore, utilizing a constructionist perspective, how these challenges evolved from a nonissue to an impending crisis in less than 25 years. Additionally, present-day efforts by researchers, policymakers, and practitioners to address these challenges will be explored and recommendations will be made for future directions.
Unternehmen in der sozial-ökologischen Transformation
Authors: Scholl Gerd , Mewes Heike
Published: March 2016

Einführung in das Schwerpunktthema
Transformative Potenziale von Unternehmen, die nicht wachsen wollen
Authors: Mewes Heike , Gebauer Jana
Published: March 2016

Sozial-ökologischer Wandel erfordert eine radikale Veränderung unserer Märkte durch nachhaltige Angebote. Die Annahme, dass hierfür die guten Unternehmen bloß wachsen müssten, greift aber zu kurz. Postwachstumsunternehmen verändern Märkte und Wirtschaftsweisen auch, wenn sie selbst nicht wachsen wollen.
The impact of economic trends on environmental policy-making
Authors: Steinebach Yves , Knill Christoph
Published: March 2016

In order to explore the relationship between environmental policy-making and economic trends we propose a measurement concept that adopts an aggregate view on the development of policy actions. In a second step, we apply our concept to environmental policy-making and contrast the observed patterns with macroeconomic data.
Zehn Meilensteine für eine nachhaltige Bioenergiestrategie in Deutschland
Authors: Pfeiffer Diana , Stur Bianca , Ponitka Jens , Arendt Oliver , Thrän Daniela
Published: March 2016

Die Transformation des Energiesystems von fossilen zu erneuerbaren Energieträgern ist ein erklärtes politisches Ziel. Aus dieser Absichtserklärungergibt sich die Frage der konkreten Umsetzung. Welche Rolle kann dabei die Bioenergie übernehmen?
Jenseits von Nachfrage und Angebot
Authors: Warnke Philine
Published: March 2016

Innovationspolitik ist zumeist Industriepolitik. Dabei wird die hohe gesellschaftliche Bedeutung von unspektakulären, nicht kommerziellen Alltagsinnovationen unterschätzt. Innovationspolitik muss daher auch diese kollaborativ geschaffenen Innovationen in den Blick nehmen.
Why Realists Need Tropes
Authors: Keinänen Markku , Hakkarainen Jani , Keskinen Antti
Published: March 2016

We argue that if one wishes to be a realist, one should adopt a realist ontology involving tropes instead of a Russellian ontology of property universals and objects. Either Russellian realists should adopt relata-specific relational tropes of instantiation instead of facts, or, better, convert to Neo-Aristotelian realism with monadic tropes. Regarding Neo-Aristotelian realism, we have two novel points why it fares better than Russellian realism. (1) Instantiation of property universals by tropes, and characterisation or inherence between tropes and objects, are more transparent ontological notions than relational inherence, which is assumed in Russellian realism with the relational tropes of instantiation. (2) Neo-Aristotelian realism makes better sense about abstract universals, which are a more viable option than concrete universals.
Speeding of α Decay in Strong Laser Fields
Authors: Mişicu Ş , Rizea M.
Published: March 2016

An extremely high-intensity laser interaction with a nucleus that is undergoing spontaneous α-decay is investigated in the framework of the time-dependent one-body Schrödinger equation solved by a Crank-Nicolson scheme associated with transparent boundary conditions. The wave-packet dynamics are determined for various laser intensities and frequencies for continuous waves and for sequences of few-cycle pulses. We show that pulse sequences containing an odd number of half-cycles determine an enhancement of the tunneling probability and therefore a drastic decrease of alpha half-lives compared to the field-free case and the continuous wave case.
Zinc supplementation prolongs the latency of hyperthermia-induced febrile seizures in rats
Authors: Aydın L , Erdem SR , Yazıcı C
Published: March 2016

Some studies have shown a relationship between febrile seizures and zinc levels. The lowest dose zinc supplementation in pentylenetetrazole seizure model has a protective effect. But, zinc pretreatment has no effect in maximal electroshock model. However, it is unclear how zinc supplementation affects hyperthermia-induced febrile seizures. The aim of the present study was to investigate the effects of zinc supplementation on febrile seizures in male Sprague-Dawley rats. The rats were randomly assigned to four groups. Zinc supplementation was commenced 5 days prior to febrile seizure induction by placing the animals in a water bath at 45°C. We measured the rectal temperature and determined the febrile seizure latency, duration, and stage. In the zinc-supplemented group, both the seizure latency and the rectal temperature triggering seizure initiation were significantly higher than in the other groups. We suggest that zinc supplementation can positively modulate febrile seizure pathogenesis in rats.
Butterflies (Lepidoptera: Papilionoidea and Hesperioidea) of the Private Reserve of Natural Heritage Fazenda Lontra/Saudade, Itanagra, Northern Coast of Bahia, Brazil
Authors: Paluch Márlon , Mielke Olaf Hermann Hendrik , Linhares Lucílio Matos , Silva Diego Carvalho da
Published: March 2016

The Private Reserve of Natural Heritage Fazenda Lontra/Saudade (FLS), located in the Northern Coast of Bahia state, Brazil, is the largest (1,377.33 ha) preserved Atlantic Forest area between Paraguaçu and São Francisco rivers in Bahia and Sergipe, respectively. A list of 260 species belonging to six families of butterflies is presented herein, being recorded 4 species of Papilionidae, 16 of Pieridae, 29 of Lycaenidae, 41 of Riodinidae, 87 of Nymphalidae and 83 of Hesperiidae. The butterfly community was composed mainly by widespread species commonly found in open habitats. There were also many species typical of forested areas, as such Morpho telemachus richardusFruhstorfer, 1898 (Nymphalidae: Morphini), a new record to the Northeastern Brazil.
Manager's Discretionary Power and Comparability of Financial Reports: An Analysis of the Regulatory Transition Process in Brazilian Accounting
Authors: Ribeiro Alex Mussoi , Carmo Carlos Henrique Silva do , Fávero Luiz Paulo Lopes , Carvalho L. Nelson
Published: March 2016

This research aimed to directly evaluate the impact of the accounting regulatory flexibility movement on the comparability of financial reports. The country chosen for the analysis was Brazil, because it was one of the few countries in the world where a process of regulatory change from a completely rule-based standard with a strong link to tax accounting (Lopes, 2011) to a principle-based standard with greater need for decision by managers who prepare the financial reports took place. To measure comparability, the accounting function similarity model developed by DeFranco, Kothari and Verdi (2011) was used. The companies analyzed were all listed ones with full data for the period concerned having, at least, a pair company within the same economic activity sector. To obtain the research results, we adopted a panel data model where the years 2005 to 2012 were compared to the year 2004. The results obtained prove that, on average, there was no significant decrease in the comparability level within country during the regulatory transition period in Brazil. On the contrary, there was an increase in genuine comparability in the year 2012 when compared to 2004. In the model adjusted by stepwise, the years 2011 and 2012 had a significantly higher average comparability when compared to 2004. The results found corroborate other researches addressing the quality of accounting information (Collins, Pasewark, & Riley, 2012; Psaros & Trotman, 2004; Agoglia, Doupnik, & Tsakumis, 2011) and prove the superiority of the principle-based standard also over the comparability of financial reports. The main conclusion of this research is that increasing manager's discretionary power through flexibility of accounting standards does not decrease the comparability of financial reports.
EDUCAÇÃO PERMANENTE NO CONTEXTO HOSPITALAR: A EXPERIÊNCIA QUE RESSIGNIFICA O CUIDADO EM ENFERMAGEM
Authors: Flores Giovana Ely , Oliveira Dora Lúcia Leidens de , Zocche Denise Antunes de Azambuja
Published: March 2016

Resumo O artigo aborda o processo de formação vivenciado por enfermeiras educadoras no contexto hospitalar, na perspectiva da educação permanente em saúde, com destaques para as experiências que constituíram esse processo, os sentidos dessa formação e as mudanças decorridas no desenvolvimento do cuidado de enfermagem com base nas aprendizagens significativas. Tratou-se de estudo qualitativo exploratório-descritivo, desenvolvido por meio de grupos focais com sete enfermeiras que atuavam no Programa de Educação Permanente em Enfermagem num hospital universitário, em Porto Alegre, no estado do Rio Grande do Sul, em 2010, à luz dos pressupostos da Política Nacional de Educação Permanente em Saúde. A análise de conteúdo, do tipo temático, foi realizada utilizando-se o software NVivo 8.0 para organização e categorização dos dados obtidos. Os resultados mostraram que a participação das enfermeiras no programa resultou em abertura para diversas mudanças no seu processo de trabalho e na modelagem de ensino-aprendizagem instituída, ampliando conceitos e espaços de formação com ênfase no aprendizado coletivo no trabalho e sobre ele, o que causa impacto no cuidado de enfermagem.
"EXERCÍCIOS DE RACIOCÍNIO" EM TRÊS LINGUAGENS: ENSINO DE FÍSICA NAS SÉRIES INICIAIS
Authors: Lima Maria da Conceição Barbosa , Carvalho Anna Maria Pessoa de
Published: March 2016

Com o objetivo de estudarmos a adequação de histórias infantis como instrumento de ensino de Física para crianças, elaboramos uma atividade que foi desenvolvida em uma turma do segundo ano do ensino fundamental de uma escola pública da cidade de São Paulo. Após a leitura da história, os alunos receberam um exercício de raciocínio para discutirem em pequenos grupos sem qualquer estímulo à experimentação. Depois desta etapa as crianças foram convidadas a discutirem suas idéias e/ou conclusões com toda a turma, numa grande roda. Para em seguida relatarem suas experiências, de maneira individual, através de um desenho e/ou pequena redação. Neste trabalho apresentamos a análise de suas falas durante a discussão da grande roda e a análise de seus relatos.
SURGERY VERSUS ENDOSCOPIC THERAPIES FOR EARLY CANCER AND HIGH-GRADE DYSPLASIA IN THE ESOPHAGUS: a systematic review
Authors: BUSTAMANTE Fabio Alberto Castillo , HOURNEAUX DE MOURA Eduardo Guimarães , BERNARDO Wanderley , SALLUM Rubens Antonio Aissar , IDE Edson , BABA Elisa
Published: March 2016

ABSTRACT Background Esophageal cancer occurs as a local disease in 22% of cases, and a minority of this disease is limited to the mucosa or submucosa (early lesions). Endoscopic mucosal resection, endoscopic submucosal dissection, photodynamic therapy, laser therapy, and argon plasma coagulation have emerged as alternatives to surgical resection for early lesions. Objective The aim of this systematic review is to identify studies that statistically compare survival, disease-free survival, morbidity and mortality associated with the procedure, and mortality associated with cancer in the endoscopic versus surgical therapies. Data sources A systematic review using MEDLINE, COCHRANE, EMBASE, EBSCO, LILACS, Library University of Sao Paulo, BVS, and SCOPE. Study selection Randomized controlled trial, controlled clinical trial, clinical trial, and cohort study. Criteria - Studies that statistically compare survival, disease-free survival, morbidity and mortality associated with the procedure, and mortality associated with cancer in patients who underwent endoscopic and surgical therapy for early lesions of esophageal cancer. Data extraction Independent extraction of the articles by two authors using predefined data fields, including study quality indicators. Limitation Only retrosprospective cohort studies comparing the endoscopic and surgical therapies were recovered. Results The survival rates after 3 and 5 years were different and exhibited superiority with the surgical therapies over time. Endoscopy is superior in the control of mortality related to cancer with a high rate of disease recurrence. With regard to the comorbidity and the mortality associated with the procedure, endoscopy is superior. Conclusion There is no evidence from clinical trials. In this systematic review, surgical therapies showed superiority for survival, and endoscopic therapies showed superiority in the control of mortality related to cancer with a high rate of disease recurrence; also, for the comorbidity and the mortality associated with the procedure, endoscopy is superior. Prospective, controlled trials with large sample sizes are necessary to confirm the results of the current analysis.
ESOPHAGEAL CARCINOMA: IS SQUAMOUS CELL CARCINOMA DIFFERENT DISEASE COMPARED TO ADENOCARCINOMA? A transversal study in a quaternary high volume hospital in Brazil
Authors: TUSTUMI Francisco , TAKEDA Flavio Roberto , KIMURA Cintia Mayumi Sakurai , SALLUM Rubens Antônio Aissar , RIBEIRO JUNIOR Ulysses , CECCONELLO Ivan
Published: March 2016

ABSTRACT Background Esophageal cancer is one of the leading causes of mortality among the neoplasms that affect the gastrointestinal tract. There are several factors that contribute for development of an epidemiological esophageal cancer profile in a population. Objective This study aims to describe both clinically and epidemiologically the population of patients with diagnosis of esophageal cancer treated in a quaternary attention institute for cancer from January, 2009 to December, 2011, in Sao Paulo, Brazil. Methods The charts of all patients diagnosed with esophageal cancer from January, 2009, to December, 2011, in a Sao Paulo (Brazil) quaternary oncology institute were retrospectively reviewed. Results Squamous cell cancer made up to 80% of the cases of esophageal cancer. Average age at diagnosis was 60.66 years old for esophageal adenocarcinoma and 62 for squamous cell cancer, average time from the beginning of symptoms to the diagnosis was 3.52 months for esophageal adenocarcinoma and 4.2 months for squamous cell cancer. Average time for initiating treatment when esophageal cancer is diagnosed was 4 months for esophageal adenocarcinoma and 4.42 months for squamous cell cancer. There was a clear association between squamous cell cancer and head and neck cancers, as well as certain habits, such as smoking and alcoholism, while adenocarcinoma cancer showed more association with gastric cancer and gastroesophageal reflux disease. Tumoral bleeding and pneumonia were the main causes of death. No difference in survival rate was noted between the two groups. Conclusion Adenocarcinoma and squamous cell carcinoma are different diseases, but both are diagnosed in advanced stages in Brazil, compromising the patients' possibilities of cure.
Abundância de inimigos naturais de pulgões do trigo em diferentes distâncias da borda da mata
Authors: Bortolotto Orcial Ceolin , Menezes Jr Ayres de Oliveira , Hoshino Adriano Thibes
Published: March 2016

Resumo: O objetivo deste trabalho foi avaliar a abundância de inimigos naturais de pulgões do trigo (Triticum aestivum) em diferentes distâncias da borda da mata (2,0 a 200 m), nos municípios de Londrina e Ibiporã, PR, na safra 2008. No total, foram quantificados 11.316 pulgões, 682 múmias, 487 parasitoides e 20.366 predadores. Não foi observada influência consistente da distância da borda da mata sobre os pulgões e os parasitoides. Entre os predadores, a família Dolichopodidae foi a mais abundante (87,74 e 98,55% em Ibiporã e Londrina, respectivamente) e apresentou maior população próximo à borda da mata, o que indica que essa área de refúgio favorece esse predador.
Bases ósseas e musculares do corte comercial de pescoço de jacaré-do-pantanal (Caimanyacare Daudin, 1802)
Authors: Figueiredo Sandra I.S. , Araújo Luciana B.M. , Ferraz Rosa H.S. , Araújo Eugênio G.
Published: March 2016

Resumo: O jacaré-do-pantanal (Caiman yacare) é uma espécie abundante no ecossistema do Pantanal. Sua exploração comercial está regulamentada desde 1990 e se tornou um agronegócio em expansão. Para atender essa demanda, uma unidade processadora instalada em Mato Grosso, vem comercializando carne de jacaré em diferentes cortes, entre os quais o filé de dorso, oriundo do pescoço, nos últimos quatro anos. O objetivo desta pesquisa foi descrever os músculos e correspondentes bases ósseas desse corte. Para a descrição de ossos, utilizaram-se seis carcaças desossadas de exemplares juvenis de jacaré-do-pantanal, além de um exemplar adulto obtido após morte do animal, por doação, do Zoológico da UFMT. Os ossos foram macerados em água corrente, clareados com solução de água oxigenada a 10 volumes, e seus detalhes anatômicos foram descritos. Para descrever o músculo, 24 exemplares juvenis foram obtidos após abate e esfola, conservados em freezer e descongelados quando utilizados, sem qualquer fixação. Após a evisceração, foram dissecados em ambos os antímeros, para verificação de simetria de ocorrência, fixações musculares, relacões de sintopia, forma e arquitetura muscular. Verificou-se que a coluna cervical em C. yacare apresenta nove vértebras cervicais (VC), associadas com as respectivas costelas, que servem de base principal ao filé de dorso, que é constituído pela musculatura cervical, exceto os músculos intertransversais cervicais e intercostais cervicais externos.
Exploring Herbicidal Potential of Aqueous Extracts of Some Herbaceous Plants Against Parthenium Weed
Authors: SAFDAR M.E. , TANVEER A. , KHALIQ A. , ALI H.H. , BURGOS N.R.
Published: March 2016

To assess the phytotoxic potential of Achyranthes aspera, Alternanthera philoxeroides, Datura metel and Rumex dentatus against Parthenium hysterophorus, 5% (w/v on dry weight basis) aqueous extracts from root, stem, leaf, flower and whole plant were tested through a Petri plate-based germination and pot-cultured seedling bioassays. Achyranthes aspera and A. philoxeroides inhibited parthenium weed germination more than extracts from other species. Whole plant, leaf and fruit extracts of A. aspera reduced the germination percentage (5%); leaf extract from A. philoxeroides caused lower germination index (0.4), higher mean germination time (14 d) and longer time to 50% germination (13.5 d) of parthenium weed. In the foliar spray bioassay, A. aspera reduced parthenium weed shoot growth more than the other species whereas R. dentatus caused more reduction in root growth. Whole plant extract from A. aspera caused maximum reduction in parthenium weed seedling vigor index (98%) and seedling biomass (96%). The aqueous extracts of A. aspera and A. philoxeroides contained higher concentrations of phenolics viz. gallic (16.9 mg L-1), caffeic (7.4 mg L-1), chromatotropic (63.8 mg L-1), p-coumaric (10.5 mg L-1), m-coumaric (3.1 mg L-1), syringic (9.21 mg L-1) and 4 hydroxy-3-methoxy benzoic (118.6 mg L-1) acids compared with extracts of the other two species tested.
Leaching of Sulfentrazone in Soils from the Sugarcane Region in the Northeast Region of Brazil
Authors: BRAGA D.F. , FREITAS F.C.L. , ROCHA P.R.R. , ARAÚJO A.G.D. , MELO V.C.
Published: March 2016

Sulfentrazone leaching potential is dependent on soil properties such as strength and type of clay, organic matter content and pH, and may result in ineffectiveness of the product and contamination of groundwater. The objective of this study was to evaluate sulfentrazone leaching in five soils of the sugarcane region in the Northeast Region of Brazil, with different physical and chemical properties, by means of bioassay and high-performance liquid chromatography (HPLC) resolution. The experiment was conducted in a split plot in a completely randomized design. The plots had PVC columns with a 10 cm diameter and being 50 cm deep, filled with five different soil classes (quartzarenic neosol, haplic cambisol, yellowish-red latosol, yellowish-red acrisol, and haplic gleysol), and subplots for 10 depths in columns, 5 cm intervals. On top of the columns, sulfentrazone application was conducted and 12 hours later there was a simulated rainfall of 60 mm. After 72 hours, the columns were horizontally placed and longitudinally open, divided into sections of 5.0 cm. In the center of each section of the columns, soil samples were collected for chromatographic analyses and sorghum sowing was carried out as an indicator plant. The bioassay method was more sensitive to detect the presence of sulfentrazone in an assessment for chromatography soil, having provided greater herbicide mobility in quartzarenic neosol and yellowish-red latosol, whose presence was detected by the indicator plant to a depth of 45 and 35 cm, respectively. In the other soils, sulfentrazone was detected up to 20 cm deep. The intense mobility of sulfentrazone in quartzarenic neosol may result in herbicide efficiency loss in the soil because the symptoms of intoxication and the amount of herbicide detected via silica were highest between 15 cm and 35 cm depth regarding the soil surface layer (0-10 cm), indicating that sulfentrazone should be avoided in soils with such characteristics.
Estudio de la estructura y las propiedades mecánicas en un recubrimiento de circona estabilizada con 8% en mol de itria elaborado por proyección térmica por plasma a partir de suspensiones
Authors: Hurtado Francy Milena , Hernández Andrés González , Gómez María Esperanza López , Ageorges Hélène
Published: March 2016

El estudio de recubrimientos nanoestructurados fabricados mediante proyección térmica ha generado un gran interés en las últimas dos décadas debido a su considerable mejora en sus propiedades sobre todo en las propiedades físicas y mecánicas. Esta mejora resulta de reducir los tamaños de grano de su materia prima a escalas de 100 a 1000 veces más bajas comparadas con los recubrimientos convencionales microestructurados. Así, estos recubrimientos con estructuras a nivel nano y/o submicrométrica están empezando a ser usados en la industria gracias a sus sobresalientes propiedades y es fundamental el estudio de sus propiedades mecánicas para determinadas aplicaciones. En la actualidad, la indentación es la principal técnica de caracterización de recubrimientos y películas delgadas, a pesar de estar altamente influenciada por los defectos propios del recubrimiento en la vecindad de la indentación. La nanoindentación y la microindentación se presentan como la mejor opción para evaluar el comportamiento mecánico de estos recubrimientos nanoestructurados. Por esta razón, en este trabajo se analizó el efecto de la estructura de un recubrimiento de circona estabilizada con 8% en mol de itria (8YSZ) elaborado por proyección térmica por plasma a partir de suspensiones nanométricas (SPS) y su relación con sus propiedades mecánicas (dureza y módulo de elasticidad) medidas por las técnicas de nanoindentación y microindentación. El análisis de la estructura de la sección transversal mostró que el recubrimiento exhibe una estructura bimodal, la cual está compuesta por una zona con partículas nanométricas semifundidas (ZS) y lamelas con mayor grado de fusión (ZF). Los ensayos de nanoindentación mostraron una distribución de Weibull bimodal de sus propiedades mecánicas, la cual característica de este tipo de recubrimientos; mientras que la dureza (HV) y el módulo de elasticidad evaluados por microindentación, presentaron una distribución monomodal. Estos resultados de microindentación estuvieron influenciados por el área de contacto en las zonas indentadas en la estructura bimodal del recubrimiento.
Asphalt binders modified with Moringa Oleifera Lam oil
Authors: Lucena Lêda Christiane de F. Lopes , Silveira Iarly Vanderlei da , Costa Daniel Beserra da
Published: March 2016

The concern with sustainable development has driven efforts to the study of green technologies to minimize the environmental impacts without compromising pavement quality. In this scenery, the paving industry has started to research and apply warm asphalt mixtures, which are produced in lower temperatures than conventional mixtures and reduce the expenses in fuels. The warm mixtures can result from the addition of an oil, usually organic, to the conventional binder, decreasing the binder's viscosity. Moringa oleifera Lam Seeds possess an oil content varying between 38 and 40% and have antioxidant and lubricant properties. This study aimed to evaluate the changes in properties related to consistency and the effective variation of mixing and compaction temperatures due to asphalt modification with the oil of Moringa oleifera Lam as green additive. The Moringa oleifera Lam oil was extracted by pressing of seeds. Then, 6 mixtures were made using 50/70 PAC and Moringa Oleifera Lam oil in different proportions (0.5%, 1%, 1.5%, 2%, 2.5% and 3%), as well as a reference sample (pure PAC). The binders were analysed using Brookfield Viscosity, Penetration, Softening Point and Rolling Thin Film Oven (RTFOT) Tests. The results showed that the addition of Moringa oleifera Lam oil must be made for contents in the range of 0.5% to 1%, once that to these contents there is a significant reduction in machining and compaction temperatures (≈ 5 °C) without compromising the asphalt binder performance.
Utilização de argilas fibrosas e tubulares para a liberação modificadas de fármacos: uma revisão
Authors: Silva Josany Saibrosa da , Vilarinho Ana Cristina Sousa Gramoza , Barud Hernane da Silva , Silva Filho Edson Cavalcanti da , Nunes Livio Cesar Cunha
Published: March 2016

Nas últimas décadas o uso de argilominerais nas áreas de Ciência e Engenharia de Materiais tem recebido notória atenção para a sua utilização no carreamento de fármacos. Dentre os diversos tipos de argilas, as fibrosas e as tubulares tem sido utilizadas na preparação de bionanocompósitos, devido as suas propriedades inerentes, como exemplo a elevada área superficial. Esta pesquisa visou o levantamento bibliográfico da utilização das argilas tubulares e fibrosas para o carreamento de fármacos. A busca por artigos foi realizado no banco de dados Web of Science, utilizando combinação dos termos: Fibrous Clay and drug delivery, Tubular Clay and drug delivery, Halloysite and drug delivery, Imogolite and drug delivery, Palygoskite and drug delivery e Sepiolite and drug delivery. Foram encontrados o total de 36 artigos durante a pesquisa. Observou-se que a maioria dos artigos utilizam as argilas em combinação com outros materiais (com formação de compósitos e blendas), principalmente polímeros, a fim de expandir as propriedades que melhoram a vetorização de insumos farmacêuticos ativos (IFAs), tais como a modificação do tamanho dos poros, do pH, da energia de ligação entre as moléculas, entre outros. Assim, evidencia-se que o interesse pela utilização das argilas no campo terapêutico tem aumentado, mostrando a relevância de pesquisas na área de medicamentos e materiais.
Instalación de la escuela monocultural en la Araucanía, 1883-1910: dispositivos de poder y Sociedad Mapuche
Authors: Sepúlveda Juan Mansilla , Llancavil Daniel Llancavil , Chacaltana Manuel Mieres , Vargas Elizabeth Montanares
Published: March 2016

Resumen Este artículo surge de un estudio historiográfico sobre la instalación de la escuela monocultural en la región de la Araucanía, en el sur de Chile entre 1883 y 1910. El objeto es analizar a la escuela como principal dispositivo de poder que permitió legitimar la instalación e implementación del curriculum nacional chileno en territorio mapuche. En esta investigación se piensa que la comprensión de los actuales problemas interculturales que se manifiestan entre los conocimientos mapuche y saberes propios de la sociedad occidental, tienen una explicación en el modo como se instaló y proyectó la escuela en la Araucanía a fines del siglo XIX. Con el análisis teórico documental que se realiza se pretende comprender la dinámica que adquirió la escuela en un diagrama disciplinario de poder-saber que se articuló desde la capital de la República de Chile, para lograr integrar a los mapuches al proyecto Estado-Nación que había sido pensado y soñado por los grupos dirigentes oligárquicos de Chile. Así, en este texto se exponen muestras empíricas de material de archivo que han sido confrontadas con fuentes secundarias que develan la presencia de nuevos actores, tales como inspectores, visitadores de escuelas, profesores, quienes asumieron la misión de concretar el curriculum prescrito republicano en territorio indígena. Fue posible encontrar que durante la instalación de la escuela monocultural a fines del siglo XIX y comienzos de la conmemoración del primer centenario de la Independencia de Chile no hubo contextualización curricular.