bluuebunny/crossref_metadata_2025 huggingface dataset:
Ataques de animais peçonhentos no Pará: Correlação entre óbitos e soroterapia no contexto da urgência e emergência
Authors: Rocha Rafael Malcher Meira , Dias Felipe Véras , Mineshita Bruno Kenji Hosoda , Ferreira Luís Arthur Moreira , Souza Gabriel Ribeiro de , Costa Juliana Furtado Ribeiro da
Published: February 2024

Os ataques por animais peçonhentos consistem em uma problemática importante para saúde pública, sobretudo em regiões predominantemente rurais, as quais são mais sujeitas a conter um maior número desses animais. Assim, são necessários eficazes protocolos em caso de ataques de animais peçonhentos, uma vez que a soroterapia é o tratamento mais indicado e os soros precisam estar disponíveis no momento do atendimento a essas vítimas. A seguinte produção tem como objetivo correlacionar a evolução do caso de pacientes vítimas de ataques por animais peçonhentos com o tempo entre o ataque e o atendimento, bem como à aplicação da soroterapia, especificamente no estado do Pará. É um estudo quantitativo, analítico, observacional e transversal, no qual foram utilizados dados sobre ataques de animais peçonhentos de 2013 até 2022 no estado do Pará coletados no Departamento de Informática do Sistema Único de Saúde. Foi verificado que os melhores prognósticos estavam entre os pacientes que procuraram atendimento médico com uso da soroterapia de 1 a 3 horas após a picada, evoluindo para cura total, enquanto os que procuravam atendimento 6 horas após a picada possuíam maiores índices de óbito. Além disso, apesar da irregularidade dos casos no período analisado, o fator tempo de atendimento após a picada, aliado com o uso da soroterapia, representou melhores prognósticos, com taxas de cura total de aproximadamente 84% com o tempo de resposta ideal sendo de 1 hora após o ataque.
Abordagem cirúrgica no tratamento de anquilose da articulação temporomandibular
Authors: Gomes Luize Marinho , Cordeiro Layla Ferreira Sousa , Nascimento Wendy Saureana Maior de Oliveira , Araújo Felipe Nunes , Dutra Ilana Raquel Rocha , Marinho Jéssica Alves , Agostinho Cícero Newton Lemos Felício
Published: February 2024

A anquilose da articulação temporomandibular (ATM) ocorre quando o complexo disco-côndilo se une à superfície articular do osso temporal, resultando em uma alteração anatômica-funcional. Sua etiologia é multifatorial, sendo o trauma associado a fratura condilar a causa mais comum. Essa condição resulta em vários problemas funcionais, destacando-se a limitação na abertura bucal e a redução da capacidade de mastigação nos pacientes afetados. O diagnóstico é estabelecido através da correlação entre os aspectos clínicos e de imagem, possibilitando uma avaliação precisa e embasando as decisões terapêuticas. Atualmente, várias modalidades cirúrgicas são empregadas para tratar a anquilose da ATM, estas incluem artroplastia em gap, artroplastia interposicional, reconstrução articular e distração osteogênica. Nesse sentindo, o presente trabalho tem como objetivo apresentar e analisar as diferentes intervenções cirúrgicas usadas no tratamento de anquilose da ATM, oferecendo uma visão concisa das possíveis formas de tratamento. Para desenvolver o presente artigo, foram realizadas pesquisas nas bases de dados do Google Acadêmico, PubMed e SciELO. O estudo abrangeu obras publicadas entre 2013 e 2023, nos idiomas português, inglês e espanhol. Essa revisão ressaltou as várias técnicas disponíveis para abordar a anquilose da ATM. No entanto, controvérsias persistem em relação ao método padrão de tratamento, sem um consenso claro entre os pesquisadores. Independentemente da técnica adotada, é essencial que o tratamento não apenas alivie os sintomas, mas também restaure a funcionalidade do sistema estomatognático e reduza os riscos de reanquilose.
A questão da qualidade de vida relacionada ao trabalho de psicólogos que trabalham no Sistema Único de Assistência Social
Authors: Oliveira Ivy Ivanira de , Costa Márcio Luís , Justi Jadson
Published: February 2024

Este estudo teve como objetivo proporcionar uma compreensão mais aprofundada sobre os fatores que impactam a Qualidade de Vida no Trabalho dos psicólogos que atuam no Sistema Único de Assistência Social, contribuindo para a identificação de elementos que podem ser trabalhados e melhorados nesse contexto. O presente estudo enquadra-se metodologicamente como uma revisão integrativa composta de produções científicas do período compreendido de janeiro de 2015 a junho de 2022, voltada para a discussão da qualidade de vida relacionada ao trabalho de profissionais da Psicologia no Sistema Único de Assistência Social, em especial nos Centros de Referência de Assistência Social e Centro de Referência Especializado de Assistência Social. Como resultados têm-se que em 2017, 2019, 2020 e 2022 foram publicados 12 trabalhos relacionados ao tema, sendo 3 em cada ano. Em 2015 e 2016 publicou-se 1 trabalho por ano. Em 2018 e 2021, foram 4 trabalhos publicados, 2 em cada ano, fechando o total de 18 estudos. Nas considerações finais evidenciaram-se inúmeros fatores com potencial para influenciar na Qualidade de Vida no Trabalho do psicólogo no Sistema Único de Assistência Social. Entretanto, há várias intervenções possíveis para tratamentos de problemas de saúde e/ou prevenção para o bem-estar de pessoas e organizações de trabalho: mudança do funcionário, observação das características do trabalho da pessoa ou do clima organizacional, mudança no ambiente de trabalho, tratamento individual, entre outras.
Modifications to Child Restraints for Children With Disabilities – Experiences of Australian Caregivers and Health Professionals
Authors: Cook Lyndall , Bilston Lynne , Whyte Tom
Published: February 2024

All children travelling in motor vehicles must be properly secured in a size-appropriate child restraint. However, for many children with a disability, standard child restraints are not suitable, and health professionals or caregivers modify restraints. There is however little data characterising these modifications. This study examined the modifications used to assist with the restraint of children aged 0-16 years with additional needs in motor vehicles. Two anonymous online surveys, one for caregivers and one for health professionals on child restraint use and modifications to seating for children with disabilities were undertaken. The quantitative and qualitative data were analysed with descriptive statistics. Eighty-six responses were analysed (40 caregivers and 46 health professionals). The majority (95.7%) of health professionals and 22.5 percent of caregivers reported having used modifications. Additional padding for postural support was the most frequently used modification (47.7% health professionals, 10% caregivers). Specialised harnesses were the most frequently used accessory used by health professionals (47.8%), with cross chest straps most frequently used by the surveyed caregivers (10%). Challenges for children with disabilities using compliant child restraints continue to persist, despite the use of modifications. There is also a lack of evidence on the impact of the modifications on restraint performance, potentially placing children at risk.
Is there an ideal One Health Curriculum?
Authors: Stephen Craig , Kock Richard
Published: February 2024

In this podcast conversation, Craig Steven, Executive Director at the McEachran Institute, and Professor Richard Kock, Editor in Chief of Research Directions One Health, discuss the concept of One Health and its importance in addressing complex global challenges. This podcast was hosted by Martin Delahunty.
URGENSI PENGEMBANGAN GURU DALAM MENJAGA EKSISTENSI GURU PENDIDIKAN ISLAM DI ERA INDUSTRI 4.0
Authors: Hairani Esi
Published: February 2024

Artikel ini bertujuan untuk membahas pengembangan Sumber Daya Manusia (SDM) Pendidikan Islam dalam menanggapi tantangan era Industri 4.0. Metode penulisan artikel ini adalah dengan melakukan studi literatur dan analisis data untuk mendapatkan gambaran tentang dampak Industri 4.0 pada pendidikan Islam dan keterampilan yang dibutuhkan oleh guru sebagai SDM Pendidikan Islam. Selain itu, artikel ini juga membahas model pengembangan SDM guru Pendidikan Islam yang tepat untuk era Industri 4.0. Hasil penelitian menunjukkan bahwa tantangan era Industri 4.0 memerlukan SDM Pendidikan Islam yang memiliki keterampilan dan kompetensi yang berbeda dengan era sebelumnya, seperti keterampilan teknologi dan keterampilan sosial. Oleh karena itu, model pengembangan SDM guru Pendidikan Islam yang tepat harus memperhatikan pengembangan keterampilan tersebut melalui evaluasi diri, kerjasama dengan institusi atau lembaga lain, pengembangan keterampilan teknologi, pengembangan keterampilan sosial, dan pengembangan pembelajaran berkelanjutan. Dengan menerapkan model pengembangan SDM guru Pendidikan Islam yang tepat, diharapkan guru Pendidikan Islam dapat mempersiapkan siswa untuk menghadapi tantangan dan memanfaatkan peluang di era Industri 4.0.Â
Pengaruh Pembelajaran Tahfizh Qurâ€™an Terhadap Emosi Peserta Didik
Authors: Fitriani Rizky
Published: February 2024

The purpose of this study was to determine the effect of learning the Qur'an on the emotions of students in class VI SDIT Assalam Curug Tangerang Regency. This research is a quantitative research. The research was carried out at SDIT Assalam Curug Tangerang, with a population of 118 students, and the sample was drawn to 30 people as a sample. Data collection techniques are questionnaires/questionnaires, observation, and decomentation methods. The instrument validity test technique uses the Pearson Product Moment formula and is strengthened by the Statistical Product and Service Solutions (SPSS) version 26 application. And the reliability technique uses the SPSS application and there are 2 types of tables, namely cases processing summary and reliability statistics. Data analysis used statistical data analysis techniques, namely: editing, scoring, and tabulating. In this study it can be seen that the Alternative Hypothesis (Ha) is accepted and the Zero Hypothesis (Ho) is not accepted.
PENINGKATAN HASIL BELAJAR FIQIH MELALUI METODE MAKE A MATCH KELAS
Authors: Nurwahidah Siti
Published: February 2024

The purpose of this study is to find out the fiqh learning process by applying the make a match method in class VII MTs Daarul Muttaqien and to find out the fiqh learning outcomes of class VII MTs Daarul Muttaqien students after the make a match method is applied. This research is a Class Action Research (PTK) conducted collaboratively with Fiqih teachers in Class VII MTs Daarul Muttaqien. This research was carried out in two cycles with pre-action or pre-cycle activities first carried out. The subjects of this study were 28 students of class VII B MTs Daarul Muttaqien. The data collection techniques used in this study were observations, interviews and learning outcomes tests. The collected data is then analyzed through three stages, namely data reduction, data presentation and drawing conclusions. The results showed that the fiqh learning process through the application of the make a match method went well and succeeded in increasing student activities when participating in learning. Meanwhile, student learning outcomes also experienced an increase as indicated by the increase in the number of students who experienced complete learning where in pre-action it was known that only 10 students completed learning (35.71%), increased to 20 students in cycle I (71.43%) and increased again to 25 students in cycle II (89.29%).
TANTANGAN PERILAKU: PENGARUH GAME ONLINE TERHADAP PERILAKU AGRESIF SISWA MTS HASANUSSHOLIHAT
Authors: Faradis Khairuna Adzkia , Ahmad Gunaldi
Published: February 2024

The aim of this research is to determine the effect of using online games on the aggressive behavior of students at MTs Hasanusshobayar Pakulonan Barat, Tangerang Regency. This research is a descriptive quantitative correlational type. The subjects of this study were students at MTs Hasanussholihat Pakulonan Barat, Tangerang Regency. Totaling 140 students. The research sampling technique used random sampling technique. Data collection techniques are observation, interviews, questionnaires and documentation. A quantitative descriptive approach was used with correlation analysis. Data was collected from 56 respondents through questionnaires, interviews and observations. Statistical tools, including SPSS, were used for data analysis.The research revealed that 73% of respondents fell into the moderate online game usage category, while 14% and 13% fell into the low and high categories respectively. Regarding aggressive behavior, 50% fell into the low category, 43% in the medium category, and 7% in the high category. The Pearson correlation coefficient was 0.475, indicating a positive relationship between online game use and aggressive behavior. The significance value is below 0.01, indicating a statistically significant relationship. The coefficient of determination (R-squared) was 0.226, indicating that 22.6% of the variation in aggressive behavior could be explained by online game use.
O Conto dos Contos e a Narrativa Fantástica de Garrone
Authors: De Moraes Bruna Cason Torquato
Published: February 2024

Este artigo trata da análise da narrativa do filme O Conto dos Contos, do diretor italiano Matteo Garrone. Colocando cada uma de suas personagens como um tópico, analisa a ideia maniqueí­sta da separação do bem e mal comumente presente nos contos de fadas, e como o diretor transpõe tal noção para levar a seus espectadores versões mais reais e humanas dos já conhecidos arquétipos narrativos apresentados por Vladimir Propp. Não obstante, é também estudada a escolha da narração mais "grotesca", que conversa mais com os contos originais propostos pelos irmãos Grimm do que com as versões mais leves apresentadas, mais tarde, pelos estúdios Walt Disney. Com três estórias simultâneas, é ainda questionada a importância da relação entre as tramas e as personagens dentro de uma obra fí­lmica, e até que ponto as ligações que criamos entre elas nos ajudam a passar a mensagem que pretendemos. No caso d'O Conto dos Contos, veremos que a ligação quase inexistente entre as personagens não atrapalha a ideia pretendida pelo filme.
GÊNERO E SEXUALIDADE NO CINEMA ESPANHOL, NO GOVERNO SOCIALISTA PÓS-FRANQUISTA: IDENTIDADES E EROTISMO EM OS AMANTES
Authors: Medeiros André Aparecido
Published: February 2024

Esta pesquisa visa a uma investigação da representação de gênero e sexualidade no cinema espanhol, no governo socialista pós-Franco, centrada na noção de voyeurismo direcionado à mulher, com a satisfação do olhar masculino, reconhecendo a erotização feminina nesse perí­odo. Problematiza-se a forma com que a mulher é apresentada, por reforçar papéis sociais do gênero feminino que frequentemente ultrapassam as caracterí­sticas isoladas das personagens, passando a endossar e a reproduzir a visão hegemônica sobre a mulher, servindo a interesses pessoais, sociais, culturais, polí­ticos e econômicos. Assim, a mulher é representada mais pelo que o homem e a sociedade esperam dela do que pelo que ela poderia ser, se eliminadas as expectativas de gênero. Optou-se pelo estudo do filme Os Amantes (Amantes, Vicente Aranda, 1991). Constata-se que o filme possui inovações, porém elas não ocorreram buscando a satisfação do público feminino. O cinema do perí­odo, por vezes, aponta para a necessidade de a mulher servir sexualmente ao homem, ou ser por ele realizada, de modo a justificar a exaltação erótica, sendo Os Amantes um exemplo disso.
Arte conTexto: corpo como resistência
Authors: Schip Larissa
Published: February 2024

Este artigo aborda três trabalhos em ví­deo, concernentes ao documental e ao autorretrato desenvolvidos a partir da minha experiência e da minha atuação como organizadora e participante da Marcha das Vadias de Curitiba, movimento feminista contemporâneo. Estas propostas de criação se concentram tanto no uso do meu corpo como resistência quanto nas minhas sensações resultantes desse embate social. Sendo assim, esta investigação aborda o conceito da grupalidade, central para o desenvolvimento dos trabalhos, compreendendo relações libertárias entre o corpo de artista e o outro, seja o outro humano ou animal. Destacam-se, em especial, a ideia de performance como linguagem nas artes visuais e o conceito de performatividade baseado na argumentação de Judith Butler.
UM'S 30 ANOS - SOBRE MEMÓRIAS E PROPOSIÇÕES
Authors: Silva Rosemeri Rocha da
Published: February 2024

Este artigo trata da pesquisa desenvolvida no UM-Núcleo de Pesquisa Artí­sticaem Dança da UNESPAR/FAP, especificamente sobre o projeto de pesquisa intitulado UM's30 ANOS, o qual se debruça sobre a história deste grupo, durante as três décadas vividas(1987 a 2017). A proposta teve como ponto de partida revisitar as obras criadas sob o olharde três (3) colaboradores atuais que desenvolvem pesquisas colaborativas junto a estenúcleo. A meta desejada foram proposições de ações que mostrassem a memória das obrasdeste repertório, reconfigurando e criando outras obras que discutissem a processualidade,a sensorialidade e as poéticas distintas que foram se estabelecendo durante o decorrerdestes anos. Assim, este artigo apresenta um mapa organizativo deste núcleo ondeaborda as estratégias metodológicas, os conceitos que são intrí­nsecos à esta pesquisaque trata dos processos investigativos, perceptivos e cognitivos, atrelados aos processosde criaçãoartí­stica colaborativas/compartilhadas. Faz parte deste artigo a apresentação derelatos dos colaboradores sobre o processo das obras criadas neste projeto de pesquisa.PALAVRAS-CHAVE: Memória. Performatividade. Mapas. Proposições.
ABRIR ESPAÇOS: O EVENTO DANÇA PERFORMATIVA DO "UM – NÚCLEO DE PESQUISA ARTÍSTICA EM DANÇA DA UNESPAR" NO MUSEU OSCAR NIEMEYER
Authors: Silveira Danilo
Published: February 2024

O artigo em questão se edifica a partir do interesse em percepções provenientesda existência do evento Danças Performativas realizado pelo UM – Núcleo de PesquisaArtí­stica em Dança da UNESPAR nas dependências do Museu Oscar Niemeyer - MON. Odebate, neste texto, tem por interesse gerar uma ponderação que versa um discurso sobreintencionalidade e espaço, abordando a discussão sobre a relação da dança que existe emespaços não tão convencionais. O grande objetivo será construir uma reflexão a partir doestudo e análise da teoria de intencionalidade trazida por Milton Santos (2014) pensandosobre a estratégia de "abrir espaços" como possibilidade criativa do grupo estudado UM.PALAVRAS-CHAVE: Dança. Espaço. Intencionalidade. Museu.
IMAGEM, CORPO E DANÇA: IMPRECISÕES QUANTO A REPRESENTAÇÃO
Authors: Bittencourt Adriana
Published: February 2024

O presente artigo aborda a existência de conjunturas que se delineiam, nos diasatuais, na produção de conhecimento em dança. A partir de pressupostos que defendemque as imagens no corpo são seus modos de operar e de se comunicar com o mundo, é quese estabelecem relações entre as imagens no corpo e as imagens produzidas no campoda cultura, tendo como eixo central a dança. Promove a percepção de que as imagens nocorpo geram imagens nos contextos e que as mesmas estabelecem correlações. Comotodo existente, as imagens negociam e evoluem e expõem seus significados. Na evidênciaconstante da propagação de imagens em diversos contextos, a questão da representaçãotorna-se fundamental para pôr em discussão os equí­vocos que se apresentam, de formarecorrente, como í­ndices de estabilidade. Tais equí­vocos se vinculam a entendimentossobre as imagens do corpo.PALAVRAS-CHAVE: Dança. Imagens. Contextos. Representação.
MALANDRAGEM ESTÉTICA EM EXECUÇÕES INSTRUMENTAIS DE UM GUITARRISTA CUBANO
Authors: Gomes Fábio , Cit Simone
Published: February 2024

A pesquisa buscou, em um primeiro momento, investigar o que caracteriza os procedimentos malandros de acordo com o método da redução estrutural de dados sociais, presente na Dialética da Malandragem (Antonio Candido). Posteriormente, o trabalho canalizou seus esforços para identificar procedimentos malandros em execuções instrumentais de Manuel Galbán (1931 – 2011), um í­cone da guitarra cubana. Assim, o objetivo geral da pesquisa é identificar o que define uma execução malandra na guitarra elétrica, a partir do método proposto por Candido. Vale ressaltar que o método é oriundo do campo literário, mas sua amplitude permite a aplicação em outras áreas artí­sticas, como na música. Ao decorrer do processo de investigação, foram utilizados os seguintes procedimentos metodológicos: 1) pesquisa bibliográfica; 2) pesquisa fonográfica; 3) pesquisa audiovisual; 4) análise das informações sob a luz da Dialética da Malandragem. Com isso, os resultados alcançados foram o entendimento da eficácia de um método da literatura na música popular, o entendimento da malandragem estética e sua importância na arte/performance e a discussão sobre o que configura um procedimento malandro na guitarra elétrica. Por fim, o trabalho sugeriu duas considerações acerca dos procedimentos malandros que envolvem a execução instrumental de Manuel Galbán.
PERCEPÇÕES DOS ESTUDOS HISTÓRICOS NAS ARTES CÊNICAS
Authors: Campos Luiz
Published: February 2024

O presente artigo visa alimentar de forma breve, o leitor para algumas percepções no campo da história, fazendo-os entender os principais caminhos que os estudos da história percorreram, explicitando conceitos não só da história, mas também de memória, eventos históricos e os motivos que impulsionam os historiadores da atualidade, relacionando com a história do teatro. O estudo pertence ao Grupo de Pesquisa Histórica, Polí­tica e Cena da Pós-Graduação da Universidade Federal de São João Del-Rei.
UM DIÁLOGO ENTRE DANÇA E PINTURA: O HIBRIDISMO DRAMATÚGICO ENTRE PINA BAUSCH E MARK ROTHKO
Authors: Vieira Lucan
Published: February 2024

O presente trabalho traz um breve levantamento histórico através dos teóricos Silveira (2015) e Baal-Teshuva (2003) a respeito dos trabalhos de Pina Bausch e Mark Rothko a fim de introduzir o leitor em suas estéticas. Por conseguinte, ele se aprofunda em questões que vão de encontro a um diálogo entre artes e entre artistas colocando o hibridismo e a dramaturgia visual como os norteadores da conversa. Este fator é esboçado pelo entrecruzamento estético a fim de encontrar similaridades poético/visuais dos artistas entre o uso das cores; traços; gestos; movimentos; potencialidades da forma; suas relações de criação; seus entendimentos a respeito do público – e, em meio a isso, discutir e apontar onde eles se aproximam e onde se afastam poético-esteticamente.
OS JOGOS TEATRAIS E AS IDENTIDADES DE GÊNERO NO AMBITO ESCOLA
Authors: Gonçalves Célia Raquel , Martins Guaraci da Silva Lopes
Published: February 2024

O presente texto busca o aprofundamento da reflexão sobre a importância do ensino do teatro, no processo de desestabilização de discursos discriminatórios contra pessoas que manifestam a sua identidade de gênero e sexualidade para além dos padrões da heterossexualidade. Para tanto, recorreu-se à autores interessados no campo da educação, da pedagogia teatral e das relações de gênero. A pesquisa de campo também foi utilizada nesta investigação cientí­fica, trabalho este que envolveu estudantes do Ensino Fundamental em uma determinada escola da rede pública paranaense. O efetivo espaço do teatro na educação escolar brasileira permanece um desafio a ser superado, pois ainda hoje esta área de conhecimento humano é compreendida como mera atividade de recreação e entretenimento. Contudo, a pesquisa realizada evidenciou que o teatro é de suma importância em ações pedagógicas comprometidas com o ensino e aprendizagem do educando. Mais precisamente, a pedagogia teatral contribui sobremaneira no processo de questionamento das complexas relações de proibição, produção e naturalização das identidades de gênero.
A FORMAÇÃO DO ATOR: POR UM ATOR-EMANCIPADO
Authors: Ferreira Ricardo Di Carlo
Published: February 2024

A pesquisa ora apresentada possui caráter de revisão bibliográfica e dedica-se à investigação da formação atorial, da Antiguidade à Contemporaneidade, ancorando-se na análise reflexiva a respeito das pedagogias do ator, que congregam o entendimento histórico reconstruí­do sobre o artista cênico e a sua formação. Desse modo, a argumentação considera as notórias transformações das concepções metodológicas do processo de profissionalização atorial, que em seu transcorrer histórico vieram a balizar as perspectivas contemporâneas de aprendizagem sob o viés do trabalho do ator sobre si mesmo, e, portanto, a de um artista da cena que opera a partir da criação de si. Nesta esteira, este estudo ancora-se em um primeiro momento no rascunho histórico evolutivo das teorias do ator, em seguida busca identificar os aspectos operativos cogentes ao suporte de sua qualificação formal/informal nos espaços contemporâneos de formação. E, finalmente, propõe possí­veis caminhos de realização atorial ao artista da cena que venham a lhe possibilitar a sua permanência no campo atuacional pelo viés da formação de um ator-emancipado.
ENSINO DE CINEMA A PARTIR DE OFICINAS: PERSPECTIVAS DE CRIAÇÃO NA SEMANA DE ENSINO, PESQUISA E EXTENSÃO DO CURSO DE PEDAGOGIA (2018-2019)
Authors: Lima Halyne Czmola , Tinte Rita de Cássia , Cordeiro Sara Reis
Published: February 2024

Este artigo surge da experiência e reflexão sobre duas oficinas de cinema ministradas na Semana de Ensino, Pesquisa e Extensão do curso de Pedagogia da Universidade Federal do Paraná, nos anos de 2018 e 2019, que tiveram como objetivos possibilitar aos futuros docentes o contato com as artes do ví­deo, ofertando atividades de criação prática sobre audiovisual, conhecimentos teóricos sobre as relações entre cinema e educação, bem como potencialidades educativas no ambiente institucional escolar. Contendo considerações acerca do que foi observado e analisado enquanto dados qualitativos sobre as vivências dos participantes, discussões originadas a partir das demandas cinematográficas dos sujeitos (incluindo relações entre cinema e surdez; cinema e educação fí­sica; imagem e som), e os processos percorridos do ensinar ao criar, concluindo com a necessidade do cinema na escola e suas dinâmicas de apreensão, para o desenvolvimento de novas metodologias e maneiras de compreender o cinema e as artes do ví­deo enquanto patrimônio cultural e dever social da escola de disseminação.
Active trachoma: enhancing image classification using pretrained SOTA models and explainable AI
Authors: Pan Yongjun , Lan Wenyao , Xu Binbin
Published: February 2024

Background

Trachoma, an infectious disease that leads to blindness, continues to pose a significant public health challenge in over 40 countries as of 2023. The initial phase of this disease, “active trachoma” is characterized by inflammation and can be effectively treated with non-surgical interventions. However, if left untreated, it progresses to the “scarring” phase, often requiring surgical intervention. Earlier detection of “active trachoma” is critical to prevent unnecessary surgery and also to reduce the transmission of the infection. Developing accessible tools for a region with limited resources is necessary. Deep neural networks have proven their effectiveness in numerous image and vision-related tasks, yet research on “active trachoma” has received still little attention.

Method

In this study, we adapted several pre-trained state-of-the-art deep neural network models like ResNet, Xception from image classification on “active classification” task. Further experiments were also conducted in three cases: training from scratch, training from pretrained models on raw images and on region-of-interest (ROI) focused images.

Results and discussion

The results indicate that these models outperformed the previous studies using the same dataset, achieving an improvement of 6\% on detection of follicular trachomatous inflammation and 12\% for detection of intense trachomatous inflammation. Furthermore, we employed the eXplainable Artificial Intelligence tool Grad-CAM, which revealed a significant discrepancy between eyelid's geometric centroid and attention centroid from models with high classification accuracy. This finding suggests that the conventional method of selecting a region of interest based on the geometric centroid may need to be adjusted. Using XAI can offer valuable insights into understanding the classification and progression of active trachoma.
Enhancing the authenticity of animal by-products: harmonization of DNA extraction methods from novel ingredients
Authors: Filipa-Silva Andreia , Castro Raquel , Rebelo Mariana , Mota Maria J. , Almeida André , Valente Luísa M. P. , Gomes Sónia
Published: February 2024

Introduction: The increasing global pressure to explore alternative protein sources derived from animal by-products has opened-up opportunities, but it has also created the need to assess their compliance with labelling statements, to ensure consumer’s trust in the composition of both feed and food products. Assessing the authenticity of highly processed animal by-products, particularly within the rapidly expanding Halal food market, presents a significant challenge due to the lack of robust and standardized methodologies. However, the success of DNA based authenticity system is highly dependent on the extracted DNA quantity, quality, and purity ratios from heterogeneous matrices.

Material and methods: In this work, nine DNA extraction methods were tested on selected processed animal by-products with high-value and interest for the feed industry: meals from poultry meat, blood and feather, and hydrolysates from swine meat and bone, fish, and black soldier fly. The proposed DNA extraction methods are developed to specifically target swine-specific mitochondrial region, as a case study.

Results and discussion: Both the conventional CTAB method and the commercial kits, specifically Invisorb® Spin Tissue Mini and NucleoSpin™ Food, demonstrated superior extraction efficiency and quality ratios. Nevertheless, commercial kits enabled faster detection in comparison to the conventional methods. The absence of swine DNA was successfully validated and confirmed in all animal meals and hydrolysates that did not contain swine in their composition beforehand, demonstrating their compliance with the Halal market requirements.
COVID-19 in pulmonary critically ill patients: metagenomic identification of fungi and characterization of pathogenic microorganisms
Authors: Huang Changjun , Chang Siyuan , Ma Rui , Shang Yishu , Li Yuexia , Wang Yun , Feng Min , Guo Wenzhi
Published: February 2024

Background

Fungal co-infection is prevalent in critically ill patients with COVID-19. The conventional approach applied to fungal identification has relatively low sensitivity and is time-consuming. The metagenomic next-generation sequencing (mNGS) technology can simultaneously detect a variety of microorganisms, and is increasingly being used for the rapid detection and diagnosis of pathogens.

Methods

In this single-center retrospective study, we described the clinical presentation and outcomes of COVID-19 and mNGS positive for fungi in pulmonary critically ill patients during the outbreak of Omicron infection from December 2022 to January 2023.

Results

Among 43 COVID-19 patients with acute respiratory distress syndrome (ARDS) on a single intensive care unit (ICU), 10 were reported to be fungal positive using the mNGS test. The number of pathogenic microorganisms detected by mNGS was significantly higher than that via traditional methods, especially in the detection of fungi and viruses. Aspergillus infection was dominant, and most of these patients also had concurrent bacterial or viral infections. Probable or possible COVID-19-associated pulmonary aspergillosis (CAPA) was diagnosed in all 10 patients, and the prognosis was poor.

Conclusion

Patients with COVID-19 may be at increased risk of developing fungal infections as well as concurrent bacterial or viral infections, and mNGS can be a powerful tool in identifying these infections. Clinicians should be aware of the increased risk of fungal infections in COVID-19 patients, particularly those who have underlying immunocompromising conditions, and should monitor for early signs of infection.
Identification of a novel Scn3b mutation in a Chinese Brugada syndrome pedigree: implications for Nav1.5 electrophysiological properties and intracellular distribution of Nav1.5 and Navβ3
Authors: Fan Jun , Wang Shao-hua , Cao Li-li , Li Wei-jie , Sun Shao-xi , Luo Shao-ling , Pan Yi-chao , Tan Wen-liang , Wu Tian-yuan , Liu Zhen , Yu Bing-bo
Published: February 2024

Background

The Scn3b gene encodes for Navβ3, a pivotal regulatory subunit of the fast sodium channel in cardiomyocytes. However, its mutation status in the Chinese population suffering from Brugada Syndrome (BrS) has not been characterized, and the contributory pathophysiological mechanisms to disease pathology remain undefined.

Methods and Results

A Scn3b (c.260C>T, p.P87l) mutation was identified in a patient with BrS of Chinese descent. Functional analyses demonstrated that sodium channel activation for the wild type, mutant samples, and co-expression of both commenced at −55 mv and peaked at −25 mv. The mutant group exhibited a notable reduction, approximately 60%, in peak sodium channel activation current (INa) at −25 mv. The parameters for half-maximal activation voltages (V1/2) and slope factors (k) showed no significant differences when comparing wild type, mutant, and combined expression groups (P = 0.98 and P = 0.65, respectively). Additionally, no significant disparities were evident in terms of the steady-state sodium channel inactivation parameters V1/2 and k (with P-values of 0.85 and 0.25, respectively), nor were there significant differences in the activation time constant τ (P = 0.59) and late sodium current density (P = 0.23) across the wild-type, mutant, and co-expressed groups. Confocal imaging and Western blot analysis demonstrated decreased plasma membrane localization of SCN3B and SCN5A in the P87l group. Computational simulations of cardiac action potentials suggested that SCN3B P87l can alter the morphology of the action potentials within the endocardium and epicardium while reducing the peak of depolarization.

Conclusions

The pathogenic impact of the Scn3b P87l mutation predominantly originates from a reduction in peak INa activation current coupled with decreased cell surface expression of Nav1.5 and Navβ3. These alterations may influence cardiac action potential configurations and contribute to the risk of ventricular arrhythmias in individuals with BrS.
InClass – an instrument to assess classroom management in inclusive and special education with a focus on heterogeneous learning groups
Authors: Lutz Stephanie , Frey Anne , Rank Astrid , Gebhardt Markus
Published: February 2024

Organizing lessons for heterogeneous learning groups is a challenge for student teachers and novice teachers. To observe and improve classroom management during student teaching, we have developed an assessment tool. The aim of this study is to evaluate and improve the instrument “Scale for Classroom Management in Inclusive Schools (InClass)” with data from 480 student teachers in internships at elementary or special schools in Germany and Austria. The instrument consists of the three dimensions Adaptive Teaching Scale (ATS), Relationship Scale (RS), Behavior Management Scale (BMS). Confirmatory factor analyses revealed good reliable values (CFI = 0.97, TLI = 0.96, RMSEA = 0.06, SRMR = 0.04) for the three-factor InClass model and could confirm the theoretically developed scales. The latent correlations were between r = 0.74 and r = 0.63. Teachers in elementary schools also showed latent correlations between the three dimensions and their assessment of the implementation of inclusive education in the school ranging from r = 0.51 to r = 0.84. In order to meet the individual needs of all students, with and without special educational needs (SEN), novice teachers in particular should be supported in dealing with heterogeneous learning groups and in using effective classroom management. Instruments such as InClass help student teachers evaluate and reflect on instruction and therefore have an important contribution to teacher education.
Evaluating conserved domains and motifs of decapod gonadotropin-releasing hormone G protein-coupled receptor superfamily
Authors: Buckley Sean J. , Nguyen Tuan Viet , Cummins Scott F. , Elizur Abigail , Fitzgibbon Quinn P. , Smith Gregory S. , Mykles Donald L. , Ventura Tomer
Published: February 2024

G protein-coupled receptors (GPCRs) are an ancient family of signal transducers that are both abundant and consequential in metazoan endocrinology. The evolutionary history and function of the GPCRs of the decapod superfamilies of gonadotropin-releasing hormone (GnRH) are yet to be fully elucidated. As part of which, the use of traditional phylogenetics and the recycling of a diminutive set of mis-annotated databases has proven insufficient. To address this, we have collated and revised eight existing and three novel GPCR repertoires for GnRH of decapod species. We developed a novel bioinformatic workflow that included clustering analysis to capture likely GnRH receptor-like proteins, followed by phylogenetic analysis of the seven transmembrane-spanning domains. A high degree of conservation of the sequences and topology of the domains and motifs allowed the identification of species-specific variation (up to ~70%, especially in the extracellular loops) that is thought to be influential to ligand-binding and function. Given the key functional role of the DRY motif across GPCRs, the classification of receptors based on the variation of this motif can be universally applied to resolve cryptic GPCR families, as was achieved in this work. Our results contribute to the resolution of the evolutionary history of invertebrate GnRH receptors and inform the design of bioassays in their deorphanization and functional annotation.
The impacts of housing conditions on physical and mental health: a critical mini-review informed by a rapid conversion of evidence from Alidoust and Huang (2021)
Authors: Simpson Amelia , Filipe Luís , Benedetto Valerio , Hill James
Published: February 2024

This article provides a summary and critical appraisal of the systematic review conducted by Alidoust et al.
1 regarding the various effects of housing on both physical and psychological well-being. We aim to discuss the review's findings against existing published evidence to draw out policy and practical implications. Our mini-review illuminates a wide range of housing-related factors which impact on health around which we draw evidence-based policy initiatives and implications, and outline avenues for future research. This mini-review is part of the wider Rapid Conversion of Evidence Summaries (RaCES) program which aims to critically appraise systematic reviews and highlight evidence-based policy and practice implications.
Potentially harmful elements and health risk assessment in groundwater of urban industrial areas
Authors: Ishtiaq Muhammad , Khan Muhammad Jibran , Khan Said Akbar , Ghani Junaid , Ullah Zahid , Nawab Javed , Alrefaei Abdulwahed Fahad , Almutairi Mikhlid H. , Alharbi Sultan N.
Published: February 2024

Groundwater quality was investigated in three urban semi-arid multi-industrial metropolitan areas i.e. (Hayatabad Industrial Estate, Peshawar (HIEP), Gadoon Industrial Estate, Swabi (GIES) and Hattar Industrial Estate, Haripur (HIEH). The main aim of the study was to determine their physicochemical parameters, potentially harmful elements (PHEs) concentration, pollution sources and public health risks in semi-arid multi-industrial metropolitan areas of Khyber Pakhtunkhwa (KPK), Pakistan. The physicochemical parameters (pH, TDS and EC), PHEs (Cd, Zn, Pb, Cr and Ni) concentrations and Mg in drinking water sources were found within the permissible limits, except Fe, which exceeded the World Health Organization (WHO) acceptable limit. Among PHEs, Zn had the highest contribution rates of 69.6%, 58.2% and 67.64% in HIEP, GIES and HIEH, respectively, while Cd showed the lowest contribution rates (3.15%, 1.98% and 2.06%) for HIEP, GIES and HIEH respectively. Principal component analysis (PCA) showed significant correlations between parameters, with contributions of industrial effluents and wastewater discharge (46.81%), mixed sources (34.05%) and geo-genic sources (19.14%) for drinking water in the study area. The carcinogenic risk (CR) for Cd, Cr, Ni and Pb, were found within the acceptable threshold value of 1 × 10−4. This study suggests that urban groundwater should also be regularly monitored for PHEs contamination as over-extraction, industrialization and informal E-waste recycling events surges the public health risks globally, facing related environmental contamination difficulties of the urban groundwater.
Temporal dynamics of immune-stromal cell interactions in fracture healing
Authors: Capobianco Christina A. , Hankenson Kurt D. , Knights Alexander J.
Published: February 2024

Bone fracture repair is a complex, multi-step process that involves communication between immune and stromal cells to coordinate the repair and regeneration of damaged tissue. In the US, 10% of all bone fractures do not heal properly without intervention, resulting in non-union. Complications from non-union fractures are physically and financially debilitating. We now appreciate the important role that immune cells play in tissue repair, and the necessity of the inflammatory response in initiating healing after skeletal trauma. The temporal dynamics of immune and stromal cell populations have been well characterized across the stages of fracture healing. Recent studies have begun to untangle the intricate mechanisms driving the immune response during normal or atypical, delayed healing. Various in vivo models of fracture healing, including genetic knockouts, as well as in vitro models of the fracture callus, have been implemented to enable experimental manipulation of the heterogeneous cellular environment. The goals of this review are to (1): summarize our current understanding of immune cell involvement in fracture healing (2); describe state-of-the art approaches to study inflammatory cells in fracture healing, including computational and in vitro models; and (3) identify gaps in our knowledge concerning immune-stromal crosstalk during bone healing.
Does tranexamic acid have a positive effect on the outcome of older multiple trauma patients on antithrombotic drugs? An analysis using the TraumaRegister DGU®
Authors: Fitschen-Oestern Stefanie , Franke Georg Maximilian , Kirsten Nora , Lefering Rolf , Lippross Sebastian , Schröder Ove , Klüter Tim , Müller Michael , Seekamp Andreas ,   TraumaRegister DGU
Published: February 2024

Background

Acute hemorrhage is one of the most common causes of death in multiple trauma patients. Due to physiological changes, pre-existing conditions, and medication, older trauma patients are more prone to poor prognosis. Tranexamic acid (TXA) has been shown to be beneficial in multiple trauma patients with acute hemorrhage in general. The relation of tranexamic acid administration on survival in elderly trauma patients with pre-existing anticoagulation is the objective of this study. Therefore, we used the database of the TraumaRegister DGU® (TR-DGU), which documents data on severely injured trauma patients.

Methods

In this retrospective analysis, we evaluated the TR-DGU data from 16,713 primary admitted patients with multiple trauma and age > =50 years from 2015 to 2019. Patients with pre-existing anticoagulation and TXA administration (996 patients, 6%), pre-existing anticoagulation without TXA administration (4,807 patients, 28.8%), without anticoagulation as premedication but TXA administration (1,957 patients, 11.7%), and without anticoagulation and TXA administration (8,953 patients, 53.6%) were identified. A regression analysis was performed to investigate the influence of pre-existing antithrombotic drugs and TXA on mortality. A propensity score was created in patients with pre-existing anticoagulation, and matching was performed for better comparability of patients with and without TXA administration.

Results

Retrospective trauma patients who underwent tranexamic acid administration were older and had a higher ISS than patients without tranexamic acid donation. Predicted mortality (according to the RISC II Score) and observed mortality were higher in the group with tranexamic acid administration. The regression analysis showed that TXA administration was associated with lower mortality rates within the first 24 h in older patients with anticoagulation as premedication. The propensity score analysis referred to higher fluid requirement, higher requirement of blood transfusion, and longer hospital stay in the group with tranexamic acid administration. There was no increase in complications. Despite higher transfusion volumes, the tranexamic acid group had a comparable all-cause mortality rate.

Conclusion

TXA administration in older trauma patients is associated with a reduced 24-h mortality rate after trauma, without increased risk of thromboembolic events. There is no relationship between tranexamic acid and overall mortality in patients with anticoagulation as premedication. Considering pre-existing anticoagulation, tranexamic acid may be recommended in elderly trauma patients with acute bleeding.
A comparative analysis of intravenous infusion methods for low-resource environments
Authors: Tomobi Oluwakemi , Avoian Samantha , Ekwere Ifeoma , Waghmare Shivani , Diaban Fatima , Davis Gabrielle , Sy Yacine , Ogbonna Oluchi , Streete Kevin , Aryee Ebenezer , Kulasingham Vasanthini , Sampson John B.
Published: February 2024

Introduction

Intravenous (IV) therapy is a crucial aspect of care for the critically ill patient. Barriers to IV infusion pumps in low-resource settings include high costs, lack of access to electricity, and insufficient technical support. Inaccuracy of traditional drop-counting practices places patients at risk. By conducting a comparative assessment of IV infusion methods, we analyzed the efficacy of different devices and identified one that most effectively bridges the gap between accuracy, cost, and electricity reliance in low-resource environments.

Methods

In this prospective mixed methods study, nurses, residents, and medical students used drop counting, a manual flow regulator, an infusion pump, a DripAssist, and a DripAssist with manual flow regulator to collect normal saline at goal rates of 240, 120, and 60 mL/h. Participants’ station setup time was recorded, and the amount of fluid collected in 10 min was recorded (in milliliters). Participants then filled out a post-trial survey to rate each method (on a scale of 1 to 5) in terms of understandability, time consumption, and operability. Cost-effectiveness for use in low-resource settings was also evaluated.

Results

The manual flow regulator had the fastest setup time, was the most cost effective, and was rated as the least time consuming to use and the easiest to understand and operate. In contrast, the combination of the DripAssist and manual flow regulator was the most time consuming to use and the hardest to understand and operate.

Conclusion

The manual flow regulator alone was the least time consuming and easiest to operate. The DripAssist/Manual flow regulator combination increases accuracy, but this combination was the most difficult to operate. In addition, the manual flow regulator was the most cost-effective. Healthcare providers can adapt these devices to their practice environments and improve the safety of rate-sensitive IV medications without significant strain on electricity, time, or personnel resources.