bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetically-Encoded Discovery of Proteolytically Stable Bicyclic Inhibitors of Morphogen NODAL
Authors: Wong Jeffrey Y. K. , Mukherjee Raja , Bilyk Olena , Miao Jiayuan , Triana Vivian , Miskolzie Mark , Lin Yu-Shan , Henninot Antoine , Dwyer John , Kharchenko Serhii , Iampolska Anna , Volochnyuk Dmitriy , Postovit John J. , Derda Ratmir
Published: February 2021

In this manuscript, we developed a Two-fold Symmetric Linchpin (TSL) that converts readily available phage display peptides libraries made of 20 common amino acids to genetically-encoded libraries of bicyclic peptides displayed on phage. TSL combines an aldehyde-reactive group and two thiol-reactive groups; it bridges two side chains of cysteine [C] with an N-terminal aldehyde group derived from the N-terminal serine [S], yielding a novel bicyclic topology that lacks a free N-terminus. Phage display libraries of SX1CX2X3X4X5X6X7C sequences, where Xi is any amino acids but Cys, were converted to a library of bicyclic TSL-[S]X1[C]X2X3X4X5X6X7[C] peptides in 45 ± 15% yield. Using this library and protein morphogen NODAL as a target, we discovered bicyclic macrocycles that specifically antagonize NODAL-induced signaling in cancer cells. At a 10 µM concentration, two discovered bicyclic peptides completely suppressed NODAL-induced phosphorylation of SMAD2 in P19 embryonic carcinoma. The TSL-[S]Y[C]KRAHKN[C] bicycle inhibited NODAL-induced proliferation of NODAL-Tky-nu ovarian carcinoma cells with apparent IC50 1 µM. The same bicycle at 10 µM concentration did not affect the growth of the control Tky-nu cells. TSL-bicycles remained stable over the course of the 72 hour-long assays in a serum-rich cell-culture medium. We further observed general stability in mouse serum and in a mixture of proteases (PronaseTM) for 33 diverse bicyclic macrocycles of different ring sizes, amino acid sequences, and cross-linker geometries. TSL-constrained peptides expand the previously reported repertoire of phage display bicyclic architectures formed by cross-linking Cys side chains. We anticipate that it will aid the discovery of proteolytically stable bicyclic inhibitors for a variety of protein targets.
CDCP1 promotes compensatory renal growth by integrating Src and Met signaling
Authors: Kajiwara Kentaro , Yamano Shotaro , Aoki Kazuhiro , Okuzaki Daisuke , Matsumoto Kunio , Okada Masato
Published: February 2021

Compensatory growth of organs after loss of their mass and/or function is controlled by hepatocyte growth factor (HGF), but the underlying regulatory mechanisms remain elusive. Here, we show that CUB domain-containing protein 1 (CDCP1) promotes HGF-induced compensatory renal growth. Using canine kidney cells as a model of renal tubules, we found that HGF-induced temporal up-regulation of Src activity and its scaffold protein, CDCP1, and that the ablation of CDCP1 robustly abrogated HGF-induced phenotypic changes, such as morphological changes and cell growth/proliferation. Mechanistic analyses revealed that up-regulated CDCP1 recruits Src into lipid rafts to activate STAT3 associated with the HGF receptor Met, and activated STAT3 induces the expression of matrix metalloproteinases and mitogenic factors. After unilateral nephrectomy in mice, the Met-STAT3 signaling is transiently up-regulated in the renal tubules of the remaining kidney, whereas CDCP1 ablation attenuates regenerative signaling and significantly suppresses compensatory growth. These findings demonstrate that CDCP1 plays a crucial role in controlling compensatory renal growth by focally and temporally integrating Src and Met signaling.
SARS-CoV-2 infection induces protective immunity and limits transmission in Syrian hamsters
Authors: Selvaraj Prabhuanand , Lien Christopher Z , Liu Shufeng , Stauft Charles B , Nunez Ivette A , Hernandez Mario , Nimako Eric , Ortega Mario A , Starost Matthew F , Dennis John U , Wang Tony T
Published: February 2021

A critical question in understanding the immunity to SARS-COV-2 is whether recovered patients are protected against re-challenge and transmission upon second exposure. We developed a Syrian hamster model in which intranasal inoculation of just 100 TCID50 virus caused viral pneumonia. Aged hamsters developed more severe disease and even succumbed to SARS-CoV-2 infection, representing the first lethal model using genetically unmodified laboratory animals. After initial viral clearance, the hamsters were re-challenged with 105 TCID50 SARS-CoV-2 and displayed more than 4 log reduction in median viral loads in both nasal washes and lungs in comparison to primary infections. Most importantly, re-challenged hamsters were unable to transmit virus to naïve hamsters, and this was accompanied by the presence of neutralizing antibodies. Altogether, these results show that SARS-CoV-2 infection induces protective immunity that not only prevents re-exposure but also limits transmission in hamsters. These findings may help guide public health policies and vaccine development and aid evaluation of effective vaccines against SARS-CoV-2.
Problems of the labor market of the Russian Federation and its legal support in the context of economic recession and pandemic
Authors: Shumilina Vera , Sidorina Tat'yana , Onopchenko Mikhail , Drobotenko Valeria , Varchenko Anna , Bondareva Kristina , Tepegendjiyan Anguelina , Filev Dmitriy , Krasnyanskaya Ekaterina , Matyushova Ellina , Pilyuk Darya , Krikunova Valentina , Goloschapova Tat'yana , Ignatenko Tat'yana , Volkova Vladislava
Published: February 2021

Today, in a modern market economy, one of the main factors of production is the labor market. The labor market and its mechanisms regulate the levels of employment of the population, supply and demand for labor, the level of wages, and the characteristics of the distribution of labor.
To study the labor market, it is necessary to collect statistical data and analyze them. Labor market statistics are an important component of socio-economic statistics. It is closely related to other sections of socio-economic statistics, such as population statistics, statistics of economic sectors, the system of national accounts, etc. The conclusions drawn from the statistical study of the labor market characterize the state and development of the economy and are necessary for making informed economic and social decisions.
The main branch of law that regulates relations in the labor market is labor law. It is one of the leading, complex and most important branches of law in the Russian Federation.
In the conditions of economic recession and pandemic, new problems of the labor market of the Russian Federation and its legal support have emerged.
This monograph, dedicated to modern problems of the labor market, is the result of the joint work of teachers and students of the Department of Economic Security, Accounting and Law of the Don State Technical University.
UNEMPLOYMENT IN RUSSIA AND OTHER COUNTRIES OF THE WORLD UNDER THE INFLUENCE OF THE COVID-19 PANDEMIC
Authors: Shumilina Vera , Varchenko Anna
Published: February 2021

The chapter provides information on the unemployment rate in Russia and around the world in the context of the spread of COVID-19, and what measures have been taken to support the unemployed population
ESSENCE OF LABOR LAW IN THE RUSSIAN FEDERATION
Authors: Shumilina Vera , Bondareva Kristina
Published: February 2021

The chapter provides information on the legal system of the Russian Federation, its goals, tasks and functions, which reflect the whole essence of the relationship between the employer and the worker.
Implementation of the national project "Labor productivity and employment support" on the territory of the Rostov region
Authors: Sidorina Tat'yana , Ignatenko Tat'yana
Published: February 2021

The chapter is devoted to the study of the implementation of the national project "Labor productivity and employment support" on the territory of the Rostov region.
FACTORS AFFECTING THE RELIABILITY OF FINANCIAL REPORTING WAJO THE COUNTY LOCAL GOVERNMENT
Authors: Hajra Dian , Majid Jamaluddin
Published: February 2021

This study aims to see whether the quality of human resources, the application of accounting standards and information governance affects the financial reporting of local governments in Wajo Regency. The population of this study were all employees of the financial division of the SKPD in the scope of Wajo Regency, namely the Department of Public Works for Spatial Planning and Land, the Office of Health and the Office of Agriculture and Food Security. This type of research is quantitative research. Collecting data from filling out questionnaires. The data collected were processed using SPSS with multiple linear regression analysis to test the hypothesis. Based on the results of research, the government can ignore that the quality of human resources and the application of accounting standards have a positive effect on regional financial reporting. Meanwhile, the use of information technology has no effect on local government financial reporting. This may be due to the fact that the SKPD is lacking in maximizing the integrated computer system.
STRATEGIES FOR INCREASING THE PERFORMANCE OF EMPLOYEES IN. BANK RAKYAT INDONESIA (PERSERO) TBK UNIT BULUMARIO PASANGKAYU CITY
Authors: Arfah Muhammad
Published: February 2021

The background of this purchasing problem is taken from the presence od employees who are not in accordance with existing abilities or slills so that they do not work and are delayed in a job. The type of research used is descriptive qualitative in which the authors describe the results describe the results of observations and direct interviews with the head of the bullumary unit and employees at PT. Bank Rakyat Indonesia (Persero) Tbk Bulumario Unit Pasangkayu City. Wring the final project is the result of writing done in june to july 2020. Research as outlined in this thesis aims to determine the strategy for developing employee performance in PT. Bank Rakyat Indonesia (Persero) Tbk Bulumario Unit Pasangkayu City. The results showed that the strategy  for developing employee performance at PT. Bank Rakyat Indonesia (Persero) Tbk. Bulumario Unit In Pasangkayu City consists of 1. Improving discipline 2.Conducting training 3.Career path 4.Providing benefits to amployee 5.Maintaining good relations between employees.
EFFECT OF FINANCIAL PERFORMANCE ON COMPANY VALUE AT PT. GUDANG GARAM Tbk
Authors: Yanti Nurmi , Nurulrahmatiah Nafisah
Published: February 2021

This study was conducted to determine the effect of financial performance as measured by liquidity and solvency ratios on firm value at PT. Gudang Garam tbk in the period 2012-2018. The data used in this study are the financial statements of PT. Gudang Garam tbk from 2012-2018. The population used in this study is financial statement data for 29 years, from 1990 to 2018 with the sample used in the form of balance sheet and profit and loss statements for 7 years from 2012 to 2018. The sampling technique uses purposive sampling with data criteria in the latest publications and data. The method of analysis in this research is the method of associative statistical analysis. The data collection technique used literature study and documentation methods while the data analysis used was multiple linear regression, classical assumption test, correlation coefficient, multiple determination coefficient and hypothesis test (2-party t test) using the SPSS software program. From this study it can be concluded that the liquidity ratio has no significant effect on firm value, while the solvency ratio has no and significant effect on firm value. And simultaneous research (f test) shows that there is a significant influence between the liquidity and solvency ratios on firm value
THE EFFECT OF BUDGET PARTICIPATION, TOTAL QUALITY MANAGEMENT, AND ENVIRONMENTAL UNCERTAINTY ON MANAGERIAL PERFORMANCE KI IN PT. TONASA LINES SHIPPING IN PANKEP DISTRICT
Authors: Zulfadli Muh. , Hajering Hajering , Amiruddin Amiruddin
Published: February 2021

In this study the author has the objective to determine the effect of budget participation, total quality management and environmental uncertainty on managerial performance on PT Pelayaran Tonasa Lines in Pangkep Regency. The hypothesis of this study is: Suspected of budget participation, total quality management and environmental uncertainty have a significant impact on the performance of managerial on PT Pelayaran Tonasa Lines in Pangkep Regency.  The data required in this study is primary data in the form of respondents’ assessment of participation, total quality management, environmental uncertainty and performance of managerial. Data collection methods used in this study is the questionnaire as well as a literature review on the books related to the subject matter covered. Data analysis techniques used by Multiple Linear Regression Test, t test, F test, Coefficient of Determination Test. The results of this study indicate: (1) budget participation a positively and significantly effect on the managerial performance; (2) total quality management a positively and not significantly effect on the managerial performance; and (3) environmental uncertainty a positively and significantly effect on the managerial performance
Efeitos da temperatura e do teor de água na qualidade de grãos de canola durante o armazenamento
Authors: Haeberlin Luana , Nunes Camila Fontoura , Bilhalva Nairiane , Medeiros Elton Pilar , Paraginski Ricardo Tadeu
Published: February 2021

A canola apresenta elevado potencial de utilização no Brasil como alternativa para sistemasprodutivos de inverno. Dentre os fatores que afetam a qualidade de armazenamento da canola,a temperatura e a umidade dos grãos são os principais, pois estando inadequados aceleram asreações bioquímicas e metabólicas dos grãos que acarretam em perdas. Assim, considerandoa crescente produção de canola, o objetivo do trabalho foi determinar os efeitos da umidadedos grãos, temperatura e tempo de armazenamento seguras para manutenção da qualidade degrãos de canola armazenados. Os grãos foram armazenados por um período de 180 dias comos teores de água de 8, 10, 12 e 14% nas temperaturas de 7, 17 e 27°C, e foram avaliados osparâmetros de qualidade tecnológicos de grãos. Os resultados indicaram que as temperaturasde 17 e 27°C ocasionaram as maiores reduções de qualidade nos parâmetros avaliados dosgrãos armazenadas com 12 e 14% de umidade. A temperatura de 27°C ocasionou perdas dequalidade nas amostras armazenadas com 10% de umidade. Na temperatura de 7°C ocorreumelhor conservação das sementes nos teores de água de 8, 10 e 12% durante 180 dias dearmazenamento.
Índios, imigrantes e refugiados: os Warao e a proteção jurídica do estado brasileiro.
Authors: Marinho Cirino Carlos Alberto
Published: February 2021

O artigo busca refletir sobre a situação dos Warao, da Venezuela, na condição de índios, imigrantes e refugiados no estado de Roraima, Brasil. O trabalho é construído com base em trabalhos etnográficos que trazem registros dos elementos da cultura tradicional e das mudanças ocorridas ao longo dos anos. Traçamos o percurso migratório dos Warao, ao adentrar o território brasileiro pelo município de Pacaraima, assim, como uma discussão sobre as formas de abrigamento e as políticas públicas então criadas para minorar a situação de vulnerabilidades do grupo.  Num segundo momento, analisamos o modus vivendi dos Warao como abrigados para, depois, traçarmos um discurso sobre os dispositivos jurídicos que a garantem aos Warao, enquanto índios, imigrantes e refugiados direitos constitucionais e infraconstitucionais.
Una antropología con un compromiso ético y político: entrevista con Esteban Emilio Mosonyi
Authors: Marinho Cirino Carlos Alberto , Silva Lima Carmen Lúcia , González Muñoz Jenny
Published: February 2021

Es una gran satisfacción ofrecer a las y los lectores de la Revista EntreRios este diálogo con el doctor Esteban Emilio Mosonyi, prestigioso antropólogo conocido por su amplia producción intelectual y actuación comprometida con los pueblos indígenas y sus causas sociales. Nacido el 14 de marzo de 1939, en Budapest, Hungría, migra con su familia a Venezuela siendo aún niño, producto de los avatares de la segunda guerra mundial. De manera que ciertamente es húngarode nacimiento, pero venezolano de corazón.
Metode Quick Count dan Analisis Autokorelasi Spasial Menggunakan Indeks Moran (Studi Kasus: Pemilihan Presiden Indonesia Tahun 2019 di Kalimantan Timur)
Authors: Veronika Riska , Hayati Memi Nor , Purnamasari Ika
Published: February 2021

Quick count is a quick caculation method based on sampling that is used to show the results of the temporary vote before the official election results are published. Votes can be influenced by party bases in various regions, so the linkage of the results of vote acquisition between regions needs to be taken into account. Spatial autocorrelation is the correlation between variables and themselves based on space or region. This research has a goal to determine the difference between the results of the estimated vote acquisition using the quick count method with the results of the KPU vote and spatial autocorrelation using the Moran index to determine whether or not there is a spatial autocorrelation of the results of the vote acquisition in the presidential election. The data used is the vote acquisition data of each pair of presidential candidates in the 2019 Indonesian presidential election in East Kalimantan Province using stratified random sampling. The results of the difference between the estimated votes obtained by the quick count method and the KPU calculation is relatively small at 0.01% and from the results of the spatial autocorrelation test hypothesis it is known that there is no spatial autocorrelation of the results of the vote acquisition for each pair of Indonesian presidential candidates in 10 districts/cities in East Kalimantan in 2019.
Optimasi Laju Pengerjaan Material AISI P20 Proses Electrical Discharge Machining (EDM) Sinking Menggunakan Metode Taguchi
Authors: Rachman Farizi , Purnomo Dhika Aditya , Setiawan Tri Andi , Fajardini Ridhani Anita
Published: February 2021

Electrical Discharge Machining atau EDM merupakan proses permesinan non-konvensional. Sistem kerja EDM dengan memanfaatkan energi panas dari proses loncatan bunga api listrik (spark) akibat adanya perbedaan muatan di antara elektroda dan benda kerja yang terisi cairan dielektrik. EDM sinking secara digunakan untuk memproduksi mold dan dies. Salah satu material yang digunakan dalam industri pembuatan mold adalah AISI P20. Pada proses pembuatan mold menggunakanEDM sinking perlu memperhatikan laju pengerjaan material yang memiliki karakteristik kualitas semakin besar nilainya maka semakin baik. Nilai laju pengerjaan material yang besar dapat meminimalkan biaya produksi. Metode Taguchi digunakan dalam penelitian ini untuk menghasilkan nilai optimal laju pengerjaan material. Desain eksperimen menggunakan orthogonal array L18 untuk mengkombinasikan empat variabel proses yaitu jenis elektroda, gap voltage, on time, dan off time. Berdasarkan hasil analisa setting parameter untuk laju pengerjaan material yang optimal menggunakan tembaga, gap voltage 40 volt, on time 150 μs, dan off time 20 μs.
ANALYSIS OF BPK LEGAL BASIS FOR FORESIGHT AUDITORS FOR THE ACCELERATED ACHIEVEMENT OF THE SUSTAINABLE DEVELOPMENT GOALS
Authors: Putra Angga Kiryaditama
Published: February 2021

Law Number 15 of 2004 and Law Number 15 of 2006 only lay down the authority of the BPK in conducting audits in general and the types of audits that can be conducted by BPK. These regulations, however, do not specifically and explicitly provide the authority to the conduct of a foresight audit. Foresight audit launched by BPK in the 2016-2020 BPK Strategic Plan will be very important in the achievement of sustainable development goals (SDGs) by 2030, given that the BPK will provide feedback and suggestions on important future policies to accelerate the achievement of SDGs. Legal instruments have an important role for BPK as the legal basis for the institution in achieving the Highest Maturity Model of the Accountability Organization in conducting a foresight audit. This study employs a normative legal research method that aims to explore and study regulations that support BPK as a foresight auditor in the future. The results illustrate that the legal basis or legal instruments for the exercise of BPK’s foresight audit authority is sufficient but still needs to be improved. The addition of legal instruments and authorities can be a solution to ensure that any foresight audit performed in the future can run optimally and accelerate the achievement of the SDGs.
THE AUDIT BOARD OF THE REPUBLIC OF INDONESIA’S OPINION: BETWEEN REGIONAL FINANCIAL PERFORMANCE AND PUBLIC WELFARE (THE STUDY ON REGENCIES AND CITIES IN RIAU PROVINCE)
Authors: Saragih Golden Victor Vica Roy , Hasibuan Arby Novrika
Published: February 2021

This study aims to determine and analyze the influence of local government financial performance on public welfare with the opinion of The Audit Board of the Republic of Indonesia (BPK) as mediation. This study was quantitative using panel data of 12 regencies and cities in Riau Province. The secondary data used was local government financial performance data, public welfare data, and the opinion from BPK Riau Representative from 2014 to 2018. The data analysis tool used for the hypothesis testing was path analysis with the SEM-PLS approach. The result shows that local government financial performance has been positively and significantly correlated to the public welfare in the regencies and cities in Riau Province, but not significant to the BPK’s opinion. Besides, the BPK’s opinion also does not correlate to public welfare. These findings indicate that the opinion of BPK has not been able to verify the correlation between the local government's financial performance and public welfare. Thus, it cannot be a benchmark in predicting the public welfare level.
THE EFFECT OF HUMAN RESOURCES AND INFORMATION TECHNOLOGY ON THE REVALUATION OF GOVERNMENT FIXED ASSETS
Authors: Indra Indra
Published: February 2021

The central government has implemented a government fixed asset revaluation policy. The main objective of the policy is to present the fair value of fixed assets in the government's financial statements. However, the results of fixed asset revaluation are not accepted by the BPK and must be corrected and recorded in the government financial statements for the 2019 fiscal year. Competent human resources and the use of information technology are considered two factors needed to achieve the revaluation objectives. This study was conducted to determine the level of significance of these two factors by distributing questionnaires to BMN officers and assessors from 82 ministries/agencies throughout Indonesia. The research data were processed by path analysis method using the Structural Equation Model (SEM) partial least squares (PLS) through Smart PLS 3.3.2 software used to assess measurement models and research structural models. The results of data processing concluded that the competence of human resources and information technology has a significant effect on the revaluation of government fixed assets. However, information technology needs to be improved again because the significance value is only half that of the human resources competency value.
Avaliação dos resultados do exame papanicolaou não procurados por mulheres de uma Unidade Básica de Saúde no município de Cajazeiras – Paraíba
Authors: Fernandes Lyvia Maria , Junior Francisco Assis Cavalcante , Abreu Rogéria Mônica Seixas Xavier de , Barbosa Marcos Alan Sousa , Souza Marilena Maria de
Published: February 2021

Este trabalho é uma pesquisa documental, exploratória, com abordagem quantitativa e teve como objetivo evidenciar as infecções sexualmente transmissíveis a partir dos resultados do exame Papanicolau não procurados por mulheres em uma Unidade Básica de Saúde, no município de Cajazeiras – Paraíba, no período de janeiro de 2010 a dezembro de 2015. A amostra foi composta por 113 resultados de exames Papanicolau, entre eles 30 (26%) tiveram resultado positivo para Infecções Sexualmente Transmissíveis (ISTs), sendo que um deles apresentou positividade para duas ISTs. O resultado negativo para a doença foi encontrado em 82 (73%) dos laudos, ressaltando que houve mais 1 (1%) resultado de alteração celular possivelmente não neoplásica. Dentre os resultados positivos para ISTs, 22 (71%) corresponderam aos casos de Vaginose e 9 (29%) aos casos de Candidíase. Denota-se que existe um número acentuado de mulheres que não retornaram à Unidade Básica de Saúde estudada para recolher os laudos do exame Papanicolau que apresentaram ISTs. Evidencia-se a relevância e necessidade do retorno das pacientes para recolherem o resultado do exame e a apresentação do mesmo ao profissional competente que, em casos positivos, poderá iniciar o tratamento precocemente, impedindo a transmissão e evitando outras infecções e prováveis complicações.

Palavras-chave: Papanicolau, Infecções Sexualmente Transmissíveis, rastreamento.
Comparative analysis of the efficiency of optical and calorimetric methods for studying the near-critical state of hydrocarbon mixtures
Authors: Podnek V.E. , Voronov V.P. , Kiyachenko Yu.F. , Sirota A.S.
Published: February 2021

By the example of a binary hydrocarbon methane–pentane mixture simulating the simplest gas-condensate system, it is shown that the optical method for studying the near-critical state of hydrocarbon fluid, using the measurement of the intensity of critical opalescence in the vicinity of the liquid–gas critical point, gives more accurate and reliable results for the dew–bubble curve and values of critical parameters of the fluid than classical adiabatic calorimetry, which uses the thermogram method to record the change in the phase state of the fluid in the near-critical region.
Technogenic factors of impact on productive sediments of hydrocarbon deposits and their relation to potential deformation of the Earth’s surface
Authors: Nikonov A.I.
Published: February 2021

The article presents the results of the studies of the assessment of subsidence of the Earth’s surface above hydrocarbon fields, obtained by mathematical modeling and on the basis of field observations. The purpose of these studies is the substantiation of changes in the initial physical-mechanical and strength properties of productive deposits in the process of exposure to them by various methods of development, comparison of estimates of subsidence of the Earth’s surface obtained by calculation and geodetic methods, taking into account the heterogeneity of the geological structure of the fields and the technogenic factors of impact. It is shown that the value of the calculated surface subsidence over the field, obtained on single data of the coefficient of pore compressibility of rocks and without taking into account the impact of the applied methods of development, does not allow an objective assessment of this process over the field area. The conclusion is made about the necessity of repeated profile leveling and gravimetric observations for a real assessment of the subsidence process of the Earth’s surface, which allows to control the industrial and environmental safety of natural and natural-technogenic objects in the field.
PARTICLES SIZE AND LATTICE STRAIN EFFECT ON THE OPTICAL CONSTANTS OF Fe3O4 NANOPARTICLES
Authors: Indrayana I Putu Tedy , Tuny Margaretha Tabita
Published: February 2021

In the case of optical sensors such as the Surface Plasmon Resonance (SPR) sensor, the Fe3O4 nanoparticles play a role to boost the signal however they can increase the detection sensitivity of the biosensor. For this application, the optical properties of Fe3O4 nanoparticles need to be studied. The optical properties are described in terms of their optical constants. Therefore, this work was purposed to study the effect of the particle size and lattice strain on the optical constants of Fe3O4 nanoparticles. Samples were synthesized by using the coprecipitation technique. Two calcination temperatures, i.e., 150oC and 250oC for 4 hours were applied to the samples. Samples were characterized for their diffraction pattern and optical properties by using XRD and Specular UV-Vis Spectroscopy technique, consecutively. The particle size and lattice strain were estimated by using the Williamson-Hall (W-H) method. The effect of the particle size and their optical constants on the reflectance curve in the SPR sensor application was also performed toward a simulation by using Winspall 3.02 software. The results show that calcination temperature causes an increase in particle size and a decrease in lattice strain. The optical constants, such as absorbance (A), absorption coefficient (α), extinction coefficient (k), refractive index (n), dielectric constants (ε), optical conductivity (σ), and the Urbach energy (Eu) significantly depended on particles size and lattice strain. However, the particle size and optical constant were significantly influent the SPR angle in the reflectance curve of Fe3O4
Salvação ou salvações?
Authors: Miranda Mário de França
Published: February 2021

O artigo estuda a noção cristã de salvação, confrontando-a com a compreensão desta realidade por parte das outras religiões. Numa primeira parte se considera a salvação cristã, suas expressões históricas e a experiência que dela podemos ter. Numa segunda parte se examina a questão das salvações oferecidas pelas outras religiões e como teólogos cristãos procuram resolvê-la. Numa terceira e última parte, de cunho mais sistemático, se oferece uma reflexão teológica que mantenha a unicidade e universalidade da salvação de Jesus Cristo e respeite o sentido e o valor dos caminhos salvíficos das outras religiões.
RUIZ BAZÁN, I. Daroca: historia, arquitectura y restauración. La conservación del patrimonio monumental (1939-2012).
Authors: Castellón Valderrama Angie
Published: February 2021

Irene Ruiz Bazán presenta en este libro, publicado por la reconocida Institución Fernando el Católico de la Diputación de Zaragoza, su tesis doctoral Daroca: historia, arquitectura y restauración. La conservación del patrimonio monumental (1939-2012) en la que ha demostrado su destreza para sintetizar la historia de la conservación del patrimonio arquitectónico español desde el fin de la Guerra Civil Española hasta la actualidad, refiriendo a sus principales actores, investigadores e instrumentos de gestión, a través del ejemplo de un municipio con marcado carácter histórico, como es el citado municipio aragonés, y las intervenciones más destacadas sobre sus bienes monumentales durante la segunda mitad del siglo XX.
HERNÁNDEZ PARDOS, Antonio y FRANCO CALVO, Jesús G. (Coords.). La antigua sinagoga de Híjar. Claves de un monumento excepcional (Teruel, España) The old synagogue of Hijar. Keys to an exceptional monument (Spain). Teruel: Acrótera. Gestión del Patrimonio, 2019.
Authors: Pallarés Jiménez Miguel Ángel
Published: February 2021

“Acrótera. Gestión del Patrimonio”, con el patrocinio del Ayuntamiento de Híjar, el Instituto de Estudios Turolenses y el Grupo de Investigación ARGOS, de la Universidad de Zaragoza, ha editado una monografía sobre la sinagoga de Híjar, un monumento excepcional que se ha conservado hasta nuestros días como ermita cristiana bajo la advocación de San Antonio Abad (vulgo de San Antón), sita en el barrio homónimo. Tras dos años de rigurosas excavaciones arqueológicas llevadas a cabo por dicha empresa, dentro del proyecto de restauración del edificio, se han localizado e interpretado elementos que lo definen como el antiguo templo de la judería local en los siglos XIV y XV, lo que se había intuido desde hacía tiempo tanto por sus características formales como por su peculiar situación en el trazado urbano de Híjar. El resultado de estos trabajos ha hecho que el Gobierno de Aragón lo haya declarado Bien de Interés Cultural en marzo de 2018, máxima figura de protección legal del Patrimonio Histórico español, ya que, hasta el momento, constituye la única sinagoga medieval conservada en dicha Comunidad con suficientes certezas arqueológicas, a la espera de que se estudien los restos de las de Calatayud y Uncastillo.
ALMARCHA NÚÑEZ-HERRADOR, Esther, GARCÍA CUETOS, María Pilar y VILLENA ESPINOSA, Rafael (eds.). Spain is different. La restauración monumental en el segundo franquismo. Cuenca: Genueve Ediciones, 2019.
Authors: Iniesta Sepúlveda Víctor
Published: February 2021

El conocido eslogan turístico de la España de los años cincuenta titula este libro, que expone los resultados de un proyecto de investigación financiado por el Ministerio de Economía y Competitividad y los Fondos FEDER. La publicación, editada por Esther Almarcha Núñez-Herrador, María Pilar García Cuetos y Rafael Villena Espinosa, continúa la línea de investigación transitada en trabajos anteriores, centrados en la restauración monumental durante la posguerra y el periodo de autarquía. En esta ocasión, la etapa estudiada es el segundo franquismo, de 1959 a 1975.
La fábrica reutilizada: la contribución de la arqueología de la arquitectura al conocimiento y puesta en valor del patrimonio industrial
Authors: Medeiros Leonor
Published: February 2021

Las fábricas, que son las estructuras más representativas de la sociedad industrial, han sido modificadas, reconstruidas y ampliadas en innumerables ocasiones a lo largo de su historia, debido a su carácter funcional y adaptativo. Las huellas de estos cambios reflejan las decisiones de los propietarios, los nuevos valores estéticos, o la evolución tecnológica.Los ejemplares que han sobrevivido hasta nuestros días están profundamente amenazados, como consecuencia de la falta de comprensión de los valores de este patrimonio y de la vorágine de renovación urbana actual. Pero este patrimonio, comúnmente infravalorado en la gestión del territorio, contiene historias y conocimientos que, para estar al servicio de la sociedad actual, requieren un estudio y registro sistemático, atento y urgente.Este artículo propone, por tanto, un análisis de la contribución de las herramientas de la arqueología de la arquitectura en los trabajos de arqueología industrial, para la comprensión de las profundas transformaciones de estos objetos en cuatro etapas clave de la vida del edificio: diseño, instalación y uso, abandono, rehabilitación. Por lo tanto, se trata de llamar la atención sobre la pertinencia de este enfoque sobre el patrimonio edificado para su comprensión, documentación, interpretación y puesta en valor durante la fase de levantamiento.
Las materias de Patrimonio y Museología en el grado de Historia del Arte en universidades españolas
Authors: Arciniega Garcia Luis
Published: February 2021

Este artículo analiza la incorporación en el ámbito universitario de los contenidos de Patrimonio y Museología vinculados a la Historia del Arte. A pesar de que son inherentes al nacimiento de la disciplina, su presencia explícita en los planes de estudio es bastante reciente. Con especial protagonismo se incorporaron con la creación de la licenciatura de la Historia del Arte y, después, del grado. En este caso, a partir de su diseño bajo las exigencias del Espacio Europeo de Educación Superior (EEES). Con dicho marco, se compara la actual representación de las asignaturas de Patrimonio y Museología en el grado de Historia del Arte en las universidades españolas, así como su imbricación con los másteres oficiales. A través de gráficas y una tabla se visualiza la dispar distribución de créditos, y se analizan los resultados atendiendo a las diferentes políticas llevadas a cabo, que en algunos casos están en la raíz del concepto mismo de Historia del Arte
Critical and Analytical View on Modern Television Speech
Authors: Danilevskaja Natalija Vasiljevna , Chigovskaja-Nazarova Janina Aleksandrovna
Published: February 2021

The purpose of the study is to identify specific features of the current cultural and speech situation in television journalistic discourse. Parameters of the language norm violation in journalistic speech are systematized. The following research methods are used: observation, analysis, systematization, comparison, interpretation, generalization. The research material includes texts of the “News” and “Political Talk Show” genres represented in broadcast schedule of the central Russian TV channels. Scientific originality of the study involves a comprehensive linguo-stylistic analysis of modern television journalistic speech. The research findings are as follows: the authors prove that violations of the literary norm in television speech affect all the levels of the language system.
Creating Interdisciplinary Courses in the Process of Studying a Foreign Language at Nonlinguistic University
Authors: Voskovskaya Angela Sergejevna , Karpova Tatiana Anatoljevna
Published: February 2021

The purpose of the study is to identify educational and methodological foundations for creating interdisciplinary integrative courses. The authors consider the content and language integrated approach to studying foreign languages at nonlinguistic universities. Scientific novelty of the research lies in the fact that possibility of logical relationship between different disciplines at the university in the process of learning a foreign language is determined. As a result of the experimental study, a developed and tested author’s curriculum of an interdisciplinary course proved its effectiveness in accordance with the developed success indicators for organisation of interdisciplinary courses.
Microfield “Der zweite Gang” (“Second Courses”) as Part of Lexical-Semantic Field “das Essen” (“Food”) in E. M. Remarque’s Novel “Der schwarze Obelisk”
Authors: Kurenkova Tatyana Nikolaevna , Strekaleva Tatyana Vladimirovna
Published: February 2021

The purpose of the research is to determine the place of the microfield “Der zweite Gang” (“Second Courses”) in the structure of the lexical-semantic field “das Essen” (“Food”), to show constituents of this microfield, properties and interaction of lexical units within it. This lexical-semantic field was built on the basis of the novel “Der schwarze Obelisk” (“The Black Obelisk”) by E. M. Remarque. Scientific novelty of the research lies in the fact that the texts of E. M. Remarque’s works have not been previously studied from the standpoint of the field approach, lexis with food semantics in the novel “Der schwarze Obelisk” is analysed for the first time. As a result, the pre-created lexical-semantic field “das Essen” was studied in detail, an analysis of the lexical units that possess semantics of food and belong to the microfield “Der zweite Gang” was provided, the place of the microfield in the considered lexical-semantic field was determined, the differential features, which can be used to divide lexical units within the specified microfield, were presented, their interaction was described.
The Greek-Macedonian Conflict and Its Impact on the European Integration Process in the Balkans
Authors: Koźbiał Krzysztof
Published: February 2021

The Greek-Macedonian dispute over the name of the Macedonian country had a negative impact on the stabilization in the southern Balkan region. Its duration caused a delay in talks on the accession of the state to the Union, which have not been taken up until now. Greece’s behavior is difficult to describe in other words than destructive and devoid of deeper logic. The authorities in Athens denied the use of the term «Macedonia» by their northern neighbour, and then agreed to the name 'Northern Macedonia' at the turn of 2018 and 2019. Having made this change and signing the agreement with Greece, the authorities in Skopje probably hoped to open talks on the membership in the organization in 2019. However, this has not happened yet. Key words: North Macedonia; Greece; Greek-Macedonian conflict; European integration; Balkans; European Union.
The Situation in the Azov Sea as a Precondition for the International Dispute
Authors: Hrynchak Volodymyr
Published: February 2021

The article analyzes the legal nature, essence and content of the international disputes between Ukraine and the Russian Federation over the annexation of the Crimean Peninsula, ensuring free navigation in the Kerch Strait, and access of the Ukrainian naval vessels to the Azov Sea. It is significantly focused on the difficulty to classify this type of disputes, positive and negative sides of the phenomenon for the national interests of Ukraine and possible prospects of the conflict resolution. It is emphasized on the inadmissibility of delay from the Ukrainian side in taking protective and preventive measures in the process of the international conflict development in order to encourage the opposite side in peaceful resolution. At the same time, it is focused on the absence of active effect of the third parties’ involvement in the peaceful dispute resolution, absence of mediators and proper interest from the international organizations that tighten Ukraine’s political maneuver possibilities. Particular emphasis is put on the Russian Federation’s tactics and strategies of the international dispute resolution; its well-planned and intercorrelated policy of escalation, extension and alteration of intergovernmental allegations, abuse of rights, application of double standards, substitution of concepts, usage of international analogies to disguise its intentions and interests. It is confirmed the Russian Federation’s dominant position in the relationship with Ukraine and permanent gain of benefits, even minimal, from any situation, including the exchange of Ukrainian captured sailors. The article suggests the wider use of the information constituent of preventive measures to underestimate or devalue object and subject of the international dispute in order to distract the opposite side’s interest from the dispute. It is analyzed the feasibility of the building of the channel through the Crimean isthmus discussion. Key words: international situation; international dispute; protective measures in the international dispute; preventive measures in the international dispute.
Comparative Analysis of Tax Policy Indices of EU Countries, Central Europe Countries and Ukraine
Authors: Moskalyk Liana , Moskalyk Roman
Published: February 2021

The article analyzes the tax policies of EU member states, Central European countries and Ukraine for the period 2005–2018, in particular: the level of tax revenues, profit tax, other taxes on business, taxes on income, profits and capital gains, taxes on goods and services, labor tax and contributions, time to prepare and pay taxes, number of tax payments. As a result of the study, we see signs of convergence in tax policies of Ukraine and EU member states, especially since 2014 (after the Revolution of Dignity in Ukraine). Tax policy trends over recent years in Ukraine are most in line with those of post-socialist Central European countries. This may be a sign that Ukraine is following a similar path to tax policy reforms, as is the case of Central European countries while integrating into European Union. The important issue for Ukraine is equitable distribution of tax pressure on business (optimize) and individuals (weaken) in order to move closer to EU indicators. Key words: tax policy; tax revenues; taxation; budget; economy of Ukraine; European Union; Central European countries.
Do I dream of conscious sheep: On self as a mental construct
Authors: Le Tam-Tri
Published: February 2021

I give some demonstrations for philosophy on the self and make connection to contemporary spirituality.
Teknik Shooting Dalam Sepakbola
Authors: Aras Arsyad
Published: February 2021

Sepak bola adalah cabang olahraga yang menggunakan bola sepak terbuat dari bahan kulit dan dimainkan oleh dua tim yang beranggotakan sebelas orang serta beberapa pemain cadangan”. Untuk memenangkan permainan ini kedua tim harus memasukkan bola ke gawang lawan tanpa menggunakan tangan. Tim yang berhasil membobol bola ke gawang lawan paling banyak akan menjadi pemenangnya. Pada dasarnya shooting sangat di perlukan dalam permainana sepak bola karena inti dari sebuah permainan sepak bola yaitu gool yang di cetak melalui shooting , Teknik dasar sepak bola dapat meliputi teknik-teknik dalam menendang, menggiring, mengontrol, menyundul, merebut, melempar ke dalam.
NAFOSTED - Quỹ Phát triển khoa học và công nghệ Quốc gia: Hội đồng khoa học ngành Kinh tế học
Authors: Pape Helpe
Published: February 2021

© Copyright 2008-2021. NAFOSTED - Quỹ Phát triển khoa học và công nghệ Quốc gia.
General Solution Of Nth-Order Linear Ordinary Differential Equation With Constant Coefficients
Authors: Jha Rajnish Kumar
Published: February 2021

In this paper we present a formula for the general solution of Nth-order linear ordinary differential equation with constant coefficients as our main result. In this regard we also present two supporting results in this paper which reduce the order of the concerned differential equation by one and give the relation between the coefficients of the initial differential equation and the differential equation obtained. We also discuss about the complementary solution and homogeneous equations with regard to the main result described in this paper.
Aturan pembuktian tautologi
Authors: PRANATA ALDY SYURYO
Published: February 2021

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Predicting online behavioural responses to transcranial direct current stimulation in stroke patients with anomia
Authors: Hope Thomas , Ondobaka Sasha , Akkad Haya , Nardo Davide , Crinion Jenny
Published: February 2021

BACKGROUND: Anomia, or difficulty naming common objects, is the most common, acquired impairment of language. Effective therapeutic interventions for anomia typically involve massed practice at high doses, requiring significant investment from patients and therapists. Aphasia researchers have increasingly looked to neurostimulation to accelerate these treatment effects, but the evidence behind this intervention is sparse and inconsistent.AIM: Here, we hypothesised that group-level neurostimulation effects might belie more systematic structure at the individual level. We sought to test the hypothesis by attempting to predict the immediate (online), individual-level behavioural effect of neurostimulation in patients with anomia.METHODS: 36 stroke patients, each with anomia at least 6 months post-onset, were asked to perform naming and judgement tasks both with concurrent neurostimulation and with sham stimulation. Using clinical, (pre-stimulation) behavioural and MRI data, and Partial Least Squares regression, we attempted to predict the effect of neurostimulation on accuracies and reaction times in both tasks. Model performance was assessed via cross-validation, and performances compared to that of a null model, which predicted the mean neurostimulation effects for all patients.RESULTS: Models derived from pre-stimulation data consistently out-performed the null model when predicting neurostimulation effects on accuracies and reaction times in both judgement and naming. Notably, we could predict declines in performance just as well as improvements.CONCLUSIONS: Inter-patient variation in online responses to neurostimulation is to some extent systematic and predictable. That declines in performance were just as predictable as improvements, implies that the effect of neurostimulation on performance in patients with anomia is unlikely to be a placebo. However, the online effect of the intervention appears to be just as likely to interfere with task performance, as it is to improve performance.
Language input to infants of different socioeconomic statuses: A quantitative meta-analysis
Authors: Dailey Shannon , Bergelson Elika
Published: February 2021

This Registered Report has been accepted at Developmental Science.
2012 Music performance review on Lebanese Andrew Andraos
Authors: Gordon Anna
Published: February 2021

This research article reports and reviewsthe art performance Andrew Andraos popularly known as young Pavarotti of the Middle East. We study the music performance of this young star using Audience interviews.