bluuebunny/crossref_metadata_2025 huggingface dataset:
Способы защиты обеспечения информационной безопасности детей от интернет-угроз
Authors: Е.З. Глазунова , Д.Ф. Кабирова , К.С. Добролюбова
Published: December 2024

В статье рассматриваются проблемы и значимость информационной безопасности детей в Интернете, так как Интернет стал неотъемлемой частью нашей жизни. Дети с малых лет активно пользуются сетью для общения, обучения и развлечений. Однако с каждым днем возрастает количество и разновидности интернет-угроз, с которыми могут столкнуться дети. Информационная безопасность детей в Интернете – это важная задача, которая требует особого внимания со стороны родителей и общества. В статье представлены основные интернет-угрозы и даны рекомендации для того, чтобы обезопасить младшее поколение от негативного воздействия.

This article discusses the problems and importance of information security of children on the Internet. Since the Internet has become an integral part of our lives. Children actively use the Internet from an early age to communicate, learn and have fun. However, the number and types of Internet threats that children may face are increasing every day. It is important to know the threats of the Internet in order to protect children from their effects. The information security of children on the Internet is an important task that requires special attention from parents and society. This article presents the main Internet threats and makes recommendations in order to protect the younger generation from the negative impact of ill-wishers.
Эволюция подходов к определению объекта и методов стимулирования закупок инновационной и высокотехнологичной продукции
Authors: К.В. Лазаренко
Published: December 2024

Статья рассматривает эволюцию подходов к определению объектов и методов стимулирования закупок инновационной и высокотехнологичной продукции в России. Анализируются особенности законодательства, регулирующего государственные и муниципальные закупки и закупки отдельными видами юридических лиц. Отмечается недостаточная четкость в определениях инновационной и высокотехнологичной продукции, что затрудняет их стимулирование. Рассматриваются изменения в законодательстве, включая введение новых критериев оценки продукции. Предлагается пересмотреть понятия и улучшить координацию механизмов стимулирования для более эффективной поддержки инноваций.

The article examines the evolution of approaches to determining the objects and methods of stimulating purchases of innovative and high-tech products in Russia. The features of legislation regulating state and municipal procurement (44-FZ) and procurement by certain types of legal entities (223-FZ) are analyzed. There is a lack of clarity in the definitions of innovative and high-tech products, which makes it difficult to stimulate them. Changes in legislation are being considered, including the introduction of new criteria for evaluating products. It is proposed to revise the concepts and improve the coordination of incentive mechanisms to more effectively support innovation.
The Effect Of A Balance Of Tapioka And Wheat Flour On The Level Of Likes Of Dumbo Catfish Meatballs
Authors: Junianto Junianto , M.A Abshar , Ahmad Y Fathan , Dwi C Angga , A Ghanialy
Published: December 2024

One fish that has various benefits and an interesting taste is the African catfish (Clarias gariepinus). African catfish meat can be processed into meatball products. The level of liking for meatballs can be influenced by the type and amount of filling ingredients used. The aim of this research is to determine the balance of tapioca flour and wheat used in making African catfish meatballs to produce the most preferred product.  The research method used was experimental with a completely randomized design consisting of 4 balanced treatments of tapioca and wheat flour, namely 100%: 0%; 90% : 10%; 80% : 20%; and 7% : 30%.  The four treatments were repeated 15 times according to the number of panelists used.  The parameters observed were the level of preference for the appearance, taste, aroma and texture of African catfish meatballs.  Testing the level of liking was carried out using a hedonic test.  The panelists used were 15 semi-trained panelists.  The data were analyzed using the Friedman test to determine the effect of treatment on the level of preference for the appearance, taste, aroma and texture of African catfish meatballs.  If there is an effect then proceed with the Multiple comparison test to determine the differences between treatments.  The Bayes method was used to determine the best treatment.  Based on the research results, the best treatment was obtained from a balance of tapioca flour and wheat at 70% and 30%.  The dombu catfish meatballs obtained from this treatment had an average level of preference for appearance, aroma, texture and taste of 6.06 (usual - like); 6.06 (regular - like); 6.06 (regular - like); and 5.66 (usual- like).
The Role of Insulin-Like Growth Factor (IGF-1) Signaling During Physical Exercise: A Systematic Review
Authors: Ayubi Novadri , Wibawa Junian Cahyanto , Aljunaid Mohammed , Jr. Procopio B. Dafun , Ming Jiang Wen
Published: December 2024

Exercise is one of the non-pharmacological therapies that functions to improve public health. This study seeks to determine how increased IGF-1 levels during exercise as a hormone can trigger growth. For this study, a number of journal databases were searched, such as PubMed, Web of Science, Embase, and Science Direct. This study considers several aspects, such as research on exercise and IGF-1 published in reputable journals over the past five years. Our analysis only includes items published in reputable international journals. Using databases total of 159 publications were found. In this comprehensive analysis, about ten carefully selected and peer-reviewed papers were included. The standard operating procedure for this investigation was developed using Preferred Reporting Systematics and Meta-analysis (PRISMA). Based on the results of this systemic investigation, exercise has been shown to increase IGF-1 levels, a hormone that promotes growth. Physical exercise as a therapeutic effort and a means of improving public health.
From Dustings of Snow to Wax Tablets. Forms of Remembrance in Selected Poems by Krisztina Tóth
Authors:   Sapientia Hungarian University of Transylvani, Mihály Vilma-Irén
Published: December 2024

The present study aims at discussing memory and remembrance
through their relationship with literature, more precisely, poetry. The
analysis reaches back to Plato’s dialogue about the primacy of orality over
literacy. Relying on the myth of Mnemosyne and Lethe, it then flows over
to look at poetry as a special type of remembrance. Poems seem to remain
ambiguous in nature, concealing and revealing truth at the same time.
However, through this constant hide-and-seek with the audience, as far as
their interpretations are concerned, they unravel the art of creation itself.
They bring the reader back to the origins, to the source of memories. The
practical part of the study consists of presenting and analysing contemporary
Hungarian poems by Krisztina Tóth. The poems were selected arbitrarily,
but they refer to or hint at Mnemosyne and/or memory
Music in János Térey’s Verse Novel A Legkisebb Jégkorszak [The Shortest Ice Age]
Authors:   University of Novi Sad, Kocsis Lenke
Published: December 2024

Mentioning composers, singers, bands, and well-known musical events and citing lyrics have all been well-established and commonplace practices in literature throughout the ages. The interpretation of these gestures usually resembles the process of understanding other kinds of allusions, references, and intertextuality because that is what the above listed instances ultimately are. When it comes to art forms that combine multiple forms of media, such as films, the use of music as background score, soundtrack, etc. is usually perceived as a fundamental part of the work, and its absence is always noted. Such frequent or constant appearance of music in literary works is not commonplace, and it typically means that the plot and theme of the text itself are music, or at least they are heavily music-oriented. The 2015 verse novel of János Térey is quite peculiar in this regard. On average, a song, a piece, a composer, or a band is mentioned on every seventh page of the book. The music referenced includes numerous genres from metal to pop, classical, jazz, and even hymns. The situations vary from background music on the radio to a character listening to his/her favourite song or someone reminiscing about an event. The variety of music and the situations it appears in throughout the novel indicate a conscious effort on the author’s part. The paper aims to examine how the various lyrical citations and musical references found throughout János Térey’s A Legkisebb Jégkorszak [The Shortest Ice Age] function as literary devices.
The Effect of Physical Work Environment and Extrinsic Motivation on Employee Performance at PT Kamigumi Indonesia in Bandar Lampung
Authors:   Institut Informatika dan Bisnis Darmajaya, Lampung, Indonesia, Suwardi Muhammad , Zuriana Zuriana ,   Institut Informatika dan Bisnis Darmajaya, Lampung, Indonesia
Published: December 2024

The performance of a company's employees is expected to be optimal if they pay attention to several factors, one of which is the physical work environment and extrinsic motivation. This research will show how much influence it has. The type of research used in this research is quantitative research with associative methods, the population of this research data is all 35 employees of PT Kamigumi Indonesia. The sample collection used is saturated sampling technique. The results showed that the physical work environment and extrinsic motivation had a positive impact on the performance of PT Kamigumi Indonesia employees. Thus, a company or leadership can pay attention to this factor and can be facilitated both the physical work environment and extrinsic motivation so that the company's employee performance becomes more optimal. Other studies need to also consider research on leadership style on the physical work environment, and motivation. So as to further enrich knowledge about variables that can affect employee performance.
Evaluation of Entreprenuerial Propensity and Interests of Undergraduates in Entrepreneurship Education in Selected Universities, Osun State
Authors: OGUNGBOYE Stephen Ayobami , OLADIIPO Samuel Adewale , AKINTUNDE-ADEYI Juliana Funmilayo , ALAGBE Bakare Akeem
Published: December 2024

Entrepreneurial Propensity and Interest are one of the major contributing factors to the formation, growth and development of entrepreneurship capacity in individuals by promoting self-reliance and brings about initiatives. This study examined the entrepreneurial propensity and interest (EPI) of undergraduates in the selected Universities in Osun State. This study adopted a cross-sectional survey method whereby data for the study were primarily and secondarily sourced through the administration of a structured questionnaire as well as journals and magazines with396 questionnaires administered to the respondents and 350were retrieved, suitable for the research. Descriptive statistics and inferential statistics were employed for the data analysis. The descriptive statistics included frequency counts, percentages, mean and standard deviation while the inferential statistics were regression analysis and Chi-square used to test the hypotheses. The study reveals that 55.9% of the undergraduates were interested in starting their businesses after school; it was also revealed that 34.80% do not like the approach and method used in teaching entrepreneurship in their universities. The study concluded that Personal attitude is positively related to entrepreneurial propensity and interest of undergraduates and has a statistically significant effect on it. Also, government and other stakeholders support services are positively related to entrepreneurial intention of University undergraduates. The study recommended that the students in the universities should engage more in entrepreneurship activities with their little finance and universities should encourage entrepreneurship activities.
Perceptions of Virtual Reality as a Learning Tool in Electrical and Electronic Engineering
Authors: Abeygunawardena Nuwanthi , Jathunga Thanushika
Published: December 2024

This study explores the integration of Virtual Reality (VR) into Electrical and Electronic Engineering (EEE) education, focusing on enhancing student engagement through technology- enabled learning. Expanding on earlier research showcasing VR’s effectiveness in various disciplines, this study examines its potential benefits for EEE students in Sri Lanka. Using a survey of EEE undergraduates from a Sri Lankan engineering institute, the study identifies the benefits, obstacles, and possible improvements associated with VR’s implementation in the EEE curriculum. Results reveal that VR can significantly boost student engagement and deepen understanding compared to traditional learning methods. However, challenges such as health concerns, limited content availability, and financial constraints were identified as barriers to its widespread adoption. The paper concludes with targeted recommendations to address these challenges, aiming to support sustainable VR adoption and optimize its educational value in the Sri Lankan EEE context.
Characteristics of Effective Investment Evaluation Methods for Servicescape Intangible Value Quantification
Authors: Arifin Syarah Syazwani , Mohammad Izran Sarrazin , Jalil Rohaya Abdul
Published: December 2024

Servicescape upgrades are often regarded as improvements to the intangible aspects of business performance, such as an increased sense of place, levels of comfort, safety, pleasure, inspiration, and satisfaction for both customers and employees. This presents a significant challenge for facilities managers who must convince the top management, particularly the finance department, that a proposed service scape upgrade will yield financial benefits for the business. Although investment return evaluation methods that are purportedly able to quantify intangible values exist, these methods are typically designed to measure only the monetary costs and benefits associated with a project. As a result, they may not fully capture the intangible value inherent in service scape upgrading investments. In response to this gap, the authors are conducting a research to develop an anticipated investment return calculation theoretical model for service scape upgrades based on the quantification of intangible values. This paper presents a part of the findings from the first phase of the research which focuses on identifying the essential characteristics needed for an investment return evaluation method to quantify service scape intangible values. A mix of qualitative and quantitative approach was adopted, starting with the identification of the characteristics from the literature. Twelve experts that included academics and practitioners in economic valuation, non-market valuation, and methodologies for quantifying intangible values were then interviewed to assess whether the identified characteristics are indeed required to quantify service scape intangible values. The interview data were analysed progressively using content analysis, frequency and Relative Importance Index until data saturation was achieved. The result indicates that qualitative metrics, and long-term perspective are the most important characteristics needed for an investment evaluation method to quantify service scape intangible values. These findings will help guide the selection of appropriate investment evaluation methods to be incorporated into the anticipated investment return theoretical model for service scape upgrades. This in turn may assist decision-makers alike to determine the investment return of a proposed service scape upgrading project in monetary sense despite the intangible nature of the project’s values.
Dünyada Kamu Denetim Kurumları: İngiltere, Rusya, Almanya, Hindistan, Çin, Amerika Birleşik Devletleri ve Brezilya Örneği
Authors: Altunoğlu Bilge Kaan , Damar Muhammet , Özen Ahmet
Published: December 2024

Denetim, genel olarak belirlenen standartlara, yasal düzenlemelere veya belirlenmiş prosedürlere uygunluğun değerlendirilmesi ve bu standartların, yasaların veya prosedürlerin gerektirdiği şekilde hareket edilip edilmediğinin kontrol edilmesi sürecidir. Bu süreç, finansal raporlama, iç kontrol sistemleri, yasal uyumluluk, risk yönetimi, operasyonel etkinlik ve verimlilik gibi çeşitli alanlarda gerçekleştirilebilir. Denetimin iki boyutu olup bunlardan özel sektör firmalarının denetimi ve kamu kurumlarının denetimidir. Kamu denetim kurumları kamu harcamalarının denetlenmesinde merkezi bir rol oynamakta ve hükümetin kamu fonlarını nasıl topladığını, yönettiğini ve harcadığını denetlemektedir. Bu tür denetim kamu sektöründe hesap verebilirlik süreci açısından hayati önem taşımakta ve kamu harcamalarının değerlendirilmesi için ölçütler ve izlenmesi için de düzenli bir araç sağlamaktadır. Elbette her ülkenin kendi yapısına özgü kamu denetim kurumları bulunmakta olup diğer ülke kurumlarıyla benzer veya farklılıklara sahip olabilmektedir. Nitekim bu çalışmada küresel alanda gerek ekonomik gerekse coğrafi nitelikleri itibariyle yedi ülke (Çin, İngiltere, Rusya, Almanya, Hindistan, Brezilya ve Amerika Birleşik Devletleri) belirlenmiş ve bu ülkelerin kamu denetimlerinin genel görünümü incelenmiştir. Genel olarak, kamu denetimi her ülkede önemli bir rol oynamakla birlikte her ülkede farklılık gösterebilmektedir. Bununla birlikte tüm ülkelerde temel denetim değerleri olarak bağımsızlık, şeffaflık ve hesap verebilirlik mutlaka göz önünde bulundurulmalıdır. Sonuç olarak her ülkenin kendi siyasi ve idari yapılanmasına özgü denetim kurumları mevcut olabilse de denetim hedefleri küresel çapta ortak değerler olarak dikkat çekmektedir.
Aprendendo com o Nosso Sagrado: a força dos orixás, das caboclas e caboclos, das vovós e pretos velhos na luta contra o racismo
Authors: Chagas M. S. , Versiani Maria Helena , Azeredo Thiago Botelho
Published: December 2024

Neste capítulo é discutido o papel e a importância do acervo “Nosso Sagrado”, composto por objetos religiosos afro-brasileiros transferidos para o Museu da República (RJ) em 2020, após campanhas por justiça reparatória e a pedido de lideranças religiosas que agora participam da gestão desse acervo no museu. O texto analisa como o racismo religioso contribuiu para a naturalização de desigualdades sociais, políticas e econômicas que marginalizam as religiões afro-brasileiras e seus praticantes. Os autores argumentam que o acervo "Nosso Sagrado" transcende uma coleção de objetos materiais e deve ser visto como um patrimônio cultural abrangente, incorporando as memórias e práticas religiosas de gerações que preservam e compartilham as religiosidades afro-brasileiras, incluindo o culto a orixás, caboclos, caboclas, vovós e pretos velhos. O capítulo explora, ainda, o potencial educacional e pedagógico desse acervo como ferramenta estratégica no combate ao racismo, ressaltando que a preservação do "Nosso Sagrado" envolve não apenas a conservação material, mas também o respeito, a dignidade e os direitos das pessoas que mantêm essas tradições vivas, em uma luta contínua por reparação e pela construção de uma sociedade mais justa e inclusiva.
As festas de santo como referências culturais dos quilombos de Oriximiná
Authors: Carvalho L. G.
Published: December 2024

O trabalho examina as festas de santo no contexto do inventário de referências culturais dos quilombos de Oriximiná (PA), realizado em 2013 e 2014. Esse inventário surgiu como alternativa a um processo de tombamento que, por mais de 15 anos, permaneceu suspenso no Instituto do Patrimônio Histórico e Artístico Nacional (Iphan). A autora questiona a divisão conceitual e operacional do patrimônio cultural em material e imaterial, argumentando que as festas de santo, destacadas como as celebrações mais representativas nos territórios quilombolas da região, estão intrinsecamente ligadas às edificações e às expressões culturais locais. Carvalho defende que essas festividades devem ser compreendidas em sua totalidade, exigindo uma abordagem de proteção que considere tanto os aspectos materiais quanto imateriais envolvidos.
Quilombos, reminiscências históricas e oralidade: uma análise do tombamento constitucional de quilombos em diálogo com as teorias decoloniais
Authors: Santos B. M. , Michelan Kátia Brasilino
Published: December 2024

Neste capítulo, aborda-se a proteção dos quilombos como patrimônios culturais, aprofundando essa problemática na análise da Portaria Iphan nº 135/2023, que regulamenta o procedimento para tombamento de documentos e sítios com reminiscências dos antigos quilombos. Utilizando o referencial teórico do pensamento decolonial, as autoras defendem que a implementação dessa normativa pode fortalecer políticas públicas voltadas para a reparação social no Brasil contemporâneo, promovendo uma abordagem que valoriza a memória e a cultura quilombola sob uma perspectiva de justiça histórica.
Dimensiones del ensayo benedettiano: lo performático, lo autopoético y lo agónico. Propuestas de análisis para la práctica discursiva de un intelectual comprometido.
Authors: Correa Lust Constanza
Published: December 2024

La prolífica incursión que Mario Benedetti realiza en la escritura ensayística a lo largo de toda su producción y la complejidad que este material manifiesta ponen en evidencia el carácter de práctica discursiva intelectual que este género representa. El autor uruguayo continúa con una tradición continental que aborda al ensayo como modo privilegiado de intervención social y cultural de los intelectuales (Maíz, 2004 y 2010; Weinberg, 2007 y 2019; Scarano, 1991 y 2010; Aínsa, 2014) y se sirve de este género para dar cauce a sus reflexiones y posicionamientos bajo la concepción de la obra de arte como una herramienta de transformación de la realidad circundante. Por consiguiente, sus libros de ensayos devienen un resultado procesual que reclama, para un análisis cabal de su totalidad, la contemplación de distintas dimensiones que lo atraviesan. Nuestra propuesta supone, entonces, un abordaje del ensayo benedettiano desde tres de ellas: la performativa, la autopoética y la agónica. A través de la consideración de estas aristas en que puede desmenuzarse el ensayo en tanto práctica discursiva de un intelectual comprometido (Correa Lust, 2020), se buscará ahondar sobre el valor particular que este género proporciona al estudio de la obra de uno de los escritores más comprometidos con la causa revolucionaria de los años sesenta y setenta de nuestro continente.
Ocupaciones humanas en el piedemonte oriental de la sierra de San Luis
Authors: Carrera Aizpitarte Manuel , Cena Di Matteo Malena
Published: December 2024

Las Barranquitas es un sitio localizado en el piedemonte de la sierra de San Luis. Su registro arqueológico está compuesto principalmente por artefactos líticos, y en menor medida por fragmentos cerámicos y óseos. Los materiales se obtuvieron en distintas circunstancias de recolección, por lo que fueron divididos en dos conjuntos para su análisis. El conjunto A está integrado por los ítems obtenidos sobre un camino de tierra y en la barranca adyacente, mientras que los del conjunto B proceden de prospecciones sistemáticas efectuadas en el campo que se ubica lindante al camino. En ambos conjuntos las materias primas más utilizadas son el cuarzo y las rocas silíceas. El objetivo de este trabajo es comparar la información generada en cada conjunto y vincularla con el proceso de ocupación de este espacio. Además, se busca indagar acerca de la procedencia de los recursos líticos y su relación con la gestión de rocas y los circuitos de movilidad de los grupos humanos. Las características macroscópicas de las materias primas indican que la obtención se realizó principalmente en fuentes cercanas que no implicaron grandes costos de aprovisionamiento. Por otro lado, la presencia diferencial de grupos tipológicos sugiere que el conjunto A podría presentar materiales de distintos niveles estratigráficos y correspondientes a diferentes cronologías, mientras que el conjunto B podría estar acotado a momentos más tardíos. De esta manera, se plantea que Las Barranquitas pudo haber sido un espacio ocupado reiteradas veces, desde el Holoceno temprano/medio hasta el tardío final.
Driving Continuous Improvement in Engineering Projects with AI-Enhanced Agile Testing and Machine Learning
Authors: Abhishek Goyal
Published: December 2024

Continuous improvement projects follow unique selection, deployment, and tracking processes. In today’s fast-paced engineering projects, it has become crucial to drive actionable change for continuous improvement to support the delivery of success. Software development has been a major adopter of agile approaches because of the iterative nature of the process and how well it fits the ever-changing goals of engineering projects. This article delves into the topic of how software development and engineering project management may be improved by using AI and ML in Agile testing procedures. With the help of AI, working in teams, it is possible to sort out routine processes, create more test cases, and use obtained outcomes to reasonably distribute resources and time frames. Data mining, for example, helps in predictive analysis in order to detect risks and any possible slowdown for further action to be taken. The ability to receive constant feedback from AI reinforces the Agile testing process to thereby enable fast identification of problems, better organisational cooperation and successful implementation of intricate projects. This paper discusses the methodologies of Agile testing, a role of AI in enhancing testing efficiency, and best practices for incorporating AI in Agile engineering projects
Herbal Medicines for Diabetes Mellitus
Authors: Sumeet Bankar  , Vikas Sanap  , Prashant Sirsat
Published: December 2024

Diabetes mellitus is a systemic metabolic disease characterized by hyperglycemia, hyperlipedemia, hyperaminoacidemia, and hypoinsulinaemia it leads to decrease in both insulin secretion and insulin action.1 It is frequently associated with the development of micro and macro vascular diseases which include neuropathy, nephropathy, cardiovascular and cerebrovascular diseases.2 The disease is associated with reduced quality of life and increased risk factors for mortality and morbidity
ANALISIS PENERAPAN SISTEM MANAJEMEN KESELAMATAN DAN KESEHATAN KERJA DI RSIA CAHAYA MEDIKA KECAMATAN TAMBUN UTARA
Authors: Ningsih Ningsih
Published: December 2024

Menurut Menteri Kesehatan Republik Indonesia Nomor 66 Tahun 2016 tentang keselamatan dan kesehatan kerja rumah sakit, rumah sakit merupakan lingkungan kerja yang berisiko  tinggi terhadap keselamatan dan kesehatan semua pihak yang terlibat, sumber daya manusia rumah sakit, pasien pengunjung, dan lingkungan sekitar. Penelitian ini bertujuan untuk diketahuinya informasi mendalam mengenai penerapan SMK3 mulai dari kebijakan, perencanaan, pelaksanaan, pemantauan dan laporan K3RS. Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif. Informan dalam penelitian ini adalah 3 informan yaitu Pimpinan RSIA, Kepala Bagian K3RS dan Kepala HRD RSIA. Pengumpulan data  dilakukan dengan wawancara, observasi dan telaah dokumen. Hasil penelitian menunjukan bahwa RSIA Cahaya Medika membuat kebijakan K3RS berupa komitmen K3 dan sarana & prasarana K3, membuat perencanaan K3RS dengan manajemen resiko dan dibentuknya program K3,pelaksanaan K3 akan  dilakukan  bersamaan  dengan  pelaksanaan  pelayanan  kerja  pada  karyawan  dan pengendalian  kebakaran,  melakukan  pemantauan  dan  pelaporan  K3.  Namun  RSIA Cahaya Medika tidak melakukan pemantauan sarana dan prasarana K3 secara optimal, tidak m enyusun manajemen resiko dan tidak adanya pelaporan K3RS. Saran   dari  peneliti  ini  adalah  diharapkan  dapt  meningkatkanpelaksanaan  penerapan pencatatan dan pelaporan dokumen pada semua jenis kegiatan/program K3 sehingga menjadi indikator untuk perencanaan kesehatan kerja selanjutnya.
GALILEU GALILEI
Authors: Barbosa Cloves , Wilson Tafner Junior Armando
Published: December 2024

This paper has the goals to introduce the Galilei’s contribution to science. Galilei leaved in medieval historical time. He took the Francis Bacon’s theory to make observation on skay. Galilei was a big creator of instruments to research. Galilei invented a series of instruments during your life. He involved in the context of the theories of geocentrism e heliocentrism. Because this, Galilei was problems with ecclesiastical power.
Comparison of early and late term results of onlay and sublay mesh approaches in open incisional hernia surgery
Authors: Kılavuz Hüseyin , Güngör Feyyaz , Demir Murat , Kurtuluş İdris
Published: December 2024

Aims: Despite the increase in minimally invasive techniques, open techniques continue to be frequently used in incisional hernia repairs. In open incisional hernia surgeries, onlay and sublay techniques are the most frequently preferred depending on the area where the mesh is placed. In this study, we aimed to compare these two techniques by analyzing perioperative findings.
Methods: Data from elective open incisional hernia surgeries (onlay and sublay) performed by the same surgical team in the general surgery clinic between 01.01.2023 and 31.12.2023 were retrospectively reviewed. Emergency surgeries, laparoscopic or combined surgeries, patients who did not undergo mesh repair, patients who received preoperative botulinum toxin due to “loss of domain”, patients with missing data, and patients who did not continue their follow-up were excluded from the study.
Results: The data of a total of 74 patients who met the inclusion criteria were analyzed in the study. Onlay procedure was performed in 53 (71%) patients and sublay procedure was performed in 21 (19%) patients with a retromuscular approach. No intraoperative complications were detected in any of the patients. There were statistically significant differences between the groups in terms of female gender (p: 0.007), duration of surgery (p<0.001) and duration of hospital stay (p<0.001). There were no statistically significant differences between the groups in terms of complications (p:0.42), unexpected re-admission (p:0.779) and six-month recurrence (p: 0.779).
Conclusion: Onlay or sublay techniques can be safely applied in open incisional hernia surgery because they have acceptable complication and recurrence rates. Surgical experience and patient factors are the main determinants of which technique to apply.
Investigation of the effect of disease acceptance and action status of type 2 diabetes patients receiving oral antidiabetic and insulin treatment on their compliance to treatment
Authors: Özel Çakır Filiz , İncaman Deniz , Çiftci Nurcan
Published: December 2024

Aims: This study aimed to determine the effect of disease acceptance and action status on treatment compliance in Type 2 DM patients receiving oral antidiabetic and insulin treatment.
Methods: This study is a comparative cross-sectional study. A total of 122 patients, including 61 patients receiving oral antidiabetic treatment and 61 patients receiving insulin treatment, were included in this study. The data of the study were collected with the "Individual Introduction Form", "Acceptance and Action Diabetes Questionnaire", and "Type 2 Diabetes Mellitus Treatment Patient Compliance Scale".
Results: There is a significant and negative correlation between the total score of the Acceptance and Action Diabetes Questionnaire and the total score of the Type 2 Diabetes Mellitus Treatment Patient Compliance Scale (r=-0.375; p<0.05). The study observed that as the total score of the Acceptance and Action Diabetes Questionnaire increased, the total score of the Type 2 Diabetes Mellitus Treatment Patient Compliance Scale decreased.
Conclusion: In our study, it was observed that the compliance level of type 2 DM patients using insulin or OAD was moderate, and their acceptance and action levels were above average.
Clinical characteristics of patients admitted to Samsun Training and Research Hospital from the Turkiye-Syria earthquake region
Authors: Türe Eda , Özgen Emre , Oruç Muhammet Ali , Görgün Selim , Güzel Murat
Published: December 2024

Aims: After the two major earthquakes that occurred in the Türkiye-Syria region on February 6th, 2023, earthquake casualties presented to hospitals in various centers across the country. This study aimed to analyze the characteristics of the presentations made to the emergency department and outpatient clinics of our tertiary hospital from the earthquake region after the earthquake.
Methods: A total of 1534 earthquake casualties who were admitted to the Samsun Training and Research Hospital emergency department and outpatient clinics with the diagnosis code X-34 were included in the study. The data of the patients were scanned retrospectively through the online system and age, sex, presentation date, clinic and hospitalization status were recorded.
Results: The mean age of the patients was 24.6±25.9 (range: 0-98) years. Six hundred eighty-six (44.7%) patients were male, 441 (28.7%) were age under 18 years, and 1199 (78.2%) were admitted or brought to the emergency room or intensive care units (ICUs). A total of 210 (13.7%) patients were hospitalized after being admitted or brought to the hospital. No fatalities were recorded among the earthquake casualties who presented. A total of 730 (47.6%) patients were admitted to our hospital within the first 30 days after the earthquake. The highest presentation peak period was between days 5 and 9. The mean age in women, inpatients, patients presnting to outpatient clinics, and patients from Adana, Hatay, Kahramanmaraş and Osmaniye provinces was significantly higher than the other groups (p<0.001 for each). The rates of hospitalized patients were found to be significantly higher in women (p=0.002), patients presenting to outpatient clinics (p<0.001), and patients presenting within the first 30 days after the earthquake compared to other groups (p<0.001). The rates of patients presenting to emergency rooms or ICUs were significantly higher in men (p=0.011) and in those who presented within the first 7 days after the earthquake compared with the other groups (p=0.001).
Conclusion: The findings obtained from our study indicated that the prognosis was good for earthquake casualties who presented to our hospital, which is far from the center of a major earthquake, that the highest number of presentations was between the 5th and 9th days, the period between the earthquake and the hospital admission was a determining factor in terms of the clinic presented and hospitalization, and the proximity to the center of the earthquake did not affect the prognosis in presentations. Our findings also show that the age group is an important factor in terms of the clinic of presentation, hospitalization, the period after the earthquake, and the province from which the presentation is made.
Evaluation of dyspepsia symptom severity in pediatric patients: association with endoscopic and pathological findings
Authors: Kurt Cemil Cihad , Taşar Medine Ayşin , Kırbaş Nihan , Dallar Bilge Yıldız
Published: December 2024

Aims: There is diagnostic difficulty in distinguishing between organic and functional causes of dyspepsia, which is characterized by a variety of gastrointestinal symptoms. This study aimed to evaluate the correlation between dyspeptic complaints, clinical symptoms, endoscopic findings, and pathology results in pediatric patients.
Methods: A total of 159 children aged 8-17 years with dyspeptic complaints underwent upper gastrointestinal endoscopy (UGE). The Dyspepsia Symptom Severity Index (DSSI), comprising three parts (dysmotility-like, reflux-like, and ulcer-like symptoms) and 19 questions, was used to assess symptom severity. Endoscopic procedures were performed under general anesthesia, and biopsy samples were obtained.
Results: The study included 159 patients with a median age of 15 years (ranging from 8 to 17 years). Among them, 29.1% were male (38) and 76.9% were female (121). DSSI scores were calculated for each subgroup and the total score. When assessing the relationship between chronic diseases and DSSI scores, no significant association was found (p=0.48). However, smoking showed a significant correlation with DSSI scores (p=0.01 for dysmotility-like, p=0.02 for reflux-like, and p<0.01 for ulcer-like symptoms). Gender differences were observed in DSSI scores, with girls exhibiting significantly higher median scores for dysmotility-like findings compared to boys (p=0.02). Endoscopy findings also correlated with DSSI scores, with significantly higher scores in patients with ulcers (p<0.01). Pathological findings such as esophagitis were found to have significant associations with reflux-like symptoms (p=0.04), and crypt hyperplasia was associated with ulcer-like symptoms (p=0.04) in patients with DSSI subgroup scores. However, no significant differences were found between pathology findings and dyspepsia severity, significant associations were observed between UGE findings (such as ulcers, pangastritis, erosional areas, and fragility) and ulcer-like symptoms.
Conclusion: The study found significant links between dyspepsia severity and endoscopic results, stressing the need for reliable symptom scales for pediatric patients. It also highlights smoking as a factor in dyspepsia severity in children. Further research is needed to evaluate endoscopy's effectiveness in distinguishing between organic and functional dyspepsia. The study points out the limited understanding and consensus on diagnosing and managing dyspepsia in children, calling for the development of validated symptom scales and further research into cost-effective management strategies.
Effect of lipoic acid on cisplatin-induced cardiotoxicity and inflammation in cardiomyocytes
Authors: Yazğan Yener , Çınar Ramazan , Yazğan Betül
Published: December 2024

Aims: Cisplatin (CPL) is a potent chemotherapeutic agent widely used to treat various cancers. However, CPL causes toxicity
in various tissues, including the heart. Lipoic acid (LPA) is a thiol compound with antioxidant, anti-inflammatory, and antiapoptotic properties. Although LPA has been reported to have protective effects in various cardiac diseases, the mechanisms underlying its cardio-protective effects have not been elucidated. This study aimed to establish a CPL-induced cardiotoxicity model in the H9c2 cardiomyocyte cell line, to understand the mechanisms underlying this cardiotoxicity, and to investigate the effect of LPA on cardiotoxicity.
Methods: H9c2 cardiomyocyte cells as control (CNT), CPL (40 µm), and LPA-1 (300 µm LPA, and 40 µm CPL), LPA-2 (500
µm LPA, and 40 µm CPL) in combination along with CIS were used. In the analyses made, glutathione (GSH) and glutathione
peroxidase (GSHPx) enzyme activity, lipid peroxidation [malondialdehyde, (MDA)] levels, inflammation markers interleukin
(IL) -1ß, IL-6, and tumor necrosis factor (TNF) -? levels, total oxidant/antioxidant (TOS and TAS) status levels, reactive
oxygen species (ROS) and caspase activity (Casp 3 and 9) in the cells were determined.
Results: CIS treatment caused cardiomyocyte cell toxicity and increased Casp 3, Casp 9, ROS, IL-1ß, IL-6, TNF-?, TOS, and
MDA levels while decreasing GSHPx, GSH, and TAS levels. Increased inflammation and impaired oxidant/antioxidant balance
in cardiomyocyte cells after CPL treatment were regulated by LPA treatment.
Conclusion: LPA treatment was found to have a protective effect against CPL-induced cardiotoxicity in cardiomyocyte cells.
Evaluation of the immature granulocyte count in idiopathic sudden sensorineural hearing loss
Authors: Yaşar Murat , Gülten Sedat
Published: December 2024

Aims: The purpose of our study was to show whether the immature granulocyte count (IGC) can be used as a prognostic marker in idiopathic sudden sensorineural hearing loss (ISSNHL).
Methods: This study is a retrospective case-control clinical study. Patients presenting to our clinic between June 2019 and June 2022, diagnosed with ISSNHL, and receiving the same treatment protocol were investigated. Preoperative complete blood count values of 40 normal individuals with normal hearing who presented to our clinic due to nasal septum deviation were adopted as the control group. Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) (platelet × neutrophil / lymphocyte) values were calculated in addition to IGC values in complete blood counts from the patient and control groups. The patient group was classified into treatment-responsive and non-responsive subgroups according to the results of audiological examinations performed after one month based on Siegel’s criteria. IGC, SII, NRL, and PLT values were compared between all groups.
Results: Comparison of the patient and control group’s complete blood count data revealed higher leukocyte and neutrophil counts, IGC and also NLR, PLR, and SII values in the patient group compared to the control group. However, lymphocyte counts were lower in the patient group. None of the parameters previously emerging as significant in the data of patients with healing and non-healing idiopathic sudden hearing loss were statistically significant, and IGC is of no prognostic value in ISSNHL.
Conclusion: IGC may be a novel and inexpensive indicator of ISSNHL and one easily determined with complete blood count, but it is of no prognostic value in the disease.
Impact of the COVID-19 pandemic on diagnostic breast biopsies: a retrospective comparative study
Authors: Taşkent İsmail , Ece Bünyamin , Koyun Mustafa
Published: December 2024

Aims: The purpose of this study is to evaluate and compare the quantity and pathological outcomes of diagnostic breast biopsy procedures performed in our interventional radiology unit before, during, and after the COVID-19 pandemic. This study aims to examine the influence of the COVID-19 pandemic on the quantity of biopsies performed and the rates of detecting malignancies during different time periods.
Methods: This retrospective study examined 365 patients who underwent diagnostic breast biopsies between January 2019 and January 2023. The study was approved by the hospital's ethics committee. After excluding 19 patients with inconclusive pathology results, a total of 346 patients were analyzed. Biopsies were performed utilizing 14-18 G tru-cut needles with the assistance of ultrasound guidance. Patients were classified into the following periods: pre-pandemic, pandemic, and post-pandemic. The histopathological findings were categorized as either benign or malignant. Statistical comparisons were conducted using the SPSS software, and a significance level of p<0.05 was used.
Results: The average age of the patients was 53.7 ± 15.7 years. Out of the total of 346 biopsies, 165 (47.7%) were determined to be malignant, while 177 (51.2%) were found to be benign. The distribution of biopsies was as follows: 76 (22.0%) were conducted before the pandemic, 13 (3.8%) were conducted during the pandemic, and 257 (74.3%) were conducted after the pandemic. There was a substantial decline in the number of biopsies during the pandemic compared to before the pandemic, and a significant rise in the post-pandemic period compared to both the pandemic and pre-pandemic periods (p=0.024 and p=0.041, respectively). The incidence of malignancies during the post-pandemic period was significantly greater compared to both the pre-pandemic period (p=0.045) and the pandemic period (p=0.027).
Conclusion: The COVID-19 pandemic caused substantial disruptions in breast cancer diagnostics, as indicated by a decrease in the number of biopsies performed and delays in the detection of malignancies. Following the pandemic, there was a significant rise in the incidence of malignancies, which can be attributed to the delays in diagnosing and treating these conditions during the pandemic. These findings indicate the significance for stronger healthcare strategies to reduce the effects of future crises on cancer management.
KẾT QUẢ ĐIỀU TRỊ PHẪU THUẬT GÃY MONTEGGIA Ở NGƯỜI TRƯỞNG THÀNH TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC
Authors: Vũ Văn Túc , Lê Mạnh Sơn , Đào Xuân Thành
Published: December 2024

Mục tiêu: Mô tả đặc điểm lâm sàng và hình ảnh Xquang của nhóm bệnh nhân nghiên cứu. Nhận xét kết quả phẫu thuật điều trị phẫu thuật gãy Monteggia ở người trưởng thành tại Bệnh viện Hữu nghị Việt Đức. Đối tượng và phương pháp: Mô tả cắt ngang 35 bệnh nhân (BN) gãy Monteggia ở người trưởng thành đã được chỉ định phẫu thuật tại Bệnh viện Hữu nghị Việt Đức từ 01/2019- 12/2023 bằng phân loại Bado. Lấy mẫu tất cả các bệnh nhân đủ tiêu chuẩn chọn mẫu và đồng ý tham gia nghiên cứu. Kết quả: Trong 35 BN, tuổi trung bình 35.43 ± 13.8 tuổi (thấp nhất là 19 và cao nhất là 71 tuổi), tỉ lệ (%) nam/nữ: 57.1/42.9. Kết quả gần: Về kết quả chỉnh trục và kết xương hết di lệch (32/35BN) chiếm tỉ lệ 91.4%, di lệch ít (3/35BN) chiếm tỉ lệ 8.6% và không có BN nào có kết quả kém. Về phục hồi giải phẫu chỏm quay theo tiêu chí: có 34/35 BN sau khi kết hợp xương trụ chỏm quay về vị trí, có 1/35 bệnh nhân phải mở khớp lồi cầu cánh tay - chỏm quay để đặt lại chỏm. Kết quả xa: Kết quả liền xương theo Trần Đình Chiến: liền tốt 32/35 BN chiếm 91.4%, liền xấu 8.6%, không có trường hợp nào gãy PTKX. Kết quả chung về tại thời điểm khám lại đánh giá theo thang điểm Anderson: rất tốt (24/35BN) chiếm tỷ lệ 68.6%, tốt (9/35BN) chiếm tỉ lệ 25.7% và trung bình (2/35BN) chiếm tỉ lệ 5,7% và không có kết quả kém, trong đó đánh giá chức năng khớp khủy theo Mayo Elbow Performance Score (MEPS) trung bình là 90.14±9.4 điểm (thấp nhất là 70 điểm và cao nhất là 100 điểm). Không có bệnh nhân nào bị trật lại chỏm quay sau phẫu thuật. Tất cả các trường hợp liệt thần kinh quay đều tự phục hồi sau 6 tháng mà không cần can thiệp phẫu thuật. Kết luận: Phẫu thuật kết hợp xương gãy Monteggia ở người trưởng thành là phương pháp an toàn, hiệu quả, sớm phục hồi chức năng cho cho người bệnh.
MỘT SỐ YẾU TỐ NGUY CƠ CỦA TIM BẨM SINH Ở TRẺ DƯỚI 5 TUỔI TẠI BỆNH VIỆN ĐA KHOA TỈNH TUYÊN QUANG
Authors: Nguyễn Thị Thu Hương , Lê Thị Kim Dung , Nguyễn Thị Phượng , Đỗ Thị Thu Giang
Published: December 2024

Mục tiêu: phân tích một số yếu tố nguy cơ của tim bẩm sinh ở trẻ dưới 5 tuổi tại bệnh viện Đa khoa tỉnh Tuyên Quang năm 2023-2024. Đối tượng: nhóm bệnh gồm 168 trẻ dưới 5 tuổi mắc tim bẩm sinh và nhóm chứng là 336 trẻ không mắc tim bẩm sinh và các dị tật bẩm sinh khác đến khám, điều trị tại bệnh viện Đa khoa tỉnh Tuyên Quang. Phương pháp: Nghiên cứu bệnh chứng. Kết quả: Một số yếu tố nguy cơ đến tim bẩm sinh ở trẻ dưới 5 tuổi được xác định trong nghiên cứu này bao gồm: Mẹ mắc cảm cúm (OR=2,3; 95%CI: 1,4-3,8), đái tháo đường (OR=3,2; 95%CI: 1,5-6,9), tăng huyết áp (OR=2,8; 95%CI: 1,4-5,9), mẹ đã từng phá thai hoặc sảy thai (OR=2,0; 95%CI: 1,2-3,5) và bố ≥ 40 tuổi khi mẹ mang thai (OR=4,2; 95%CI: 1,4-13,3). Kết luận: Mẹ mắc cảm cúm, đái tháo đường, tăng huyết áp khi mang thai, mẹ đã từng phá thai hoặc sảy thai và bố ≥ 40 tuổi khi mẹ mang thai là yếu tố nguy cơ của tim bẩm sinh.