bluuebunny/crossref_metadata_2025 huggingface dataset:
Comunicación oral: discurso poderoso
Authors: Garzón Puetate Wilfrido Alejandro
Published: January 2024

Este capítulo se centra en las habilidades de comunicación oral. Desde habilidades de presentación hasta manejo del lenguaje corporal, los lectores aprenderán cómo pronunciar discursos públicos impactantes. El libro ofrece consejos sobre cómo superar el miedo escénico, mejorar el tono y mantener la atención del público.
Characteristics of Bacteriological Pulmonary Tuberculosis Cases for The January – August 2021 Period at Arifin Achmad Hospital, Riau Province
Authors: Lasmaria Rohani , Febrina Nidya , Simanjutak Arya Maganda
Published: January 2024

Background: Mycobacterium tuberculosis, which causes TB, is a deadly disease that mostly affects the lungs. Surveys revealed that although there was significant variance, the estimated incidence of bacteriologically proven pulmonary TB per 100 000 people aged 15 or older was high in several countries. With multisectoral action and responsibility to address the larger causes that influence the TB epidemic and the socioeconomic effect of TB, knowing and comprehending the sociodemographic features of tuberculosis can serve as a milestone in the End TB Strategy by 2035. Methods: Descriptive cross-sectional methodology was employed in this study to collect data. 154 samples were collected over the course of eight months in accordance with the inclusion criteria; the findings are displayed as a distribution table. Results: The study's results showed that of 154 samples, patients with positive bacteriological TB were more likely to be men than women, to be in their prime working years, to be HIV-negative and to be medication sensitive. Discussion: Knowing characteristics of patients with pulmonary tuberculosis in important due to prevent higher risk of drug resistant, non-adherence treatment and mortality
Anísio Teixeira: educação como pilar da transformação social no Brasil
Authors: Da Silva Genildo Ferreira
Published: January 2024

Por que persistir em explorar a vida e a obra do intelectual e educador Anísio Teixeira? Por acreditar que sua instigante biografia, ideias e atividades práticas permanecem oferecendo um vasto terreno para análises e interpretações inovadoras. Anísio é um intelectual crucial na história da educação e na política brasileira. As suas contribuições inestimáveis provocaram uma revolução no sistema educacional do país e suas ideias perduram como fonte de inspirações e reflexões. Foi um ardoroso defensor da educação como instrumento de transformação social na sua batalha de uma vida pela democratização do ensino, a universalização do acesso à educação de qualidade, além do seu marcante trabalho na criação de escolas públicas e na implementação de políticas educacionais inovadoras. Notavelmente, a sua visão de uma educação integral transcende a mera disseminação do conhecimento académico, pois busca desenvolver habilidades sociais, culturais e éticas nos alunos. Essa perspectiva continua a ser um paradigma pertinente para moldar um sistema educacional mais inclusivo e eficaz. O compromisso inabalável de Teixeira com a educação como veículo para a promoção da igualdade de oportunidades e com o desenvolvimento humano integral é atemporal e persiste desafiando e inspirando novas gerações de pensadores e estudiosos, garantindo que seus escritos ofereçam direcionamentos significativos para os desafios e debates contemporâneos. Eis do que trata o presente texto!
Wâhkôhtowin: Gestures in Kinship, Reciprocity, and Rematriation
Authors: Felsing Lara
Published: January 2024

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Knee Deep
Authors: Gwyn Lydia
Published: January 2024

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Techniques to improve web sites positioning in the World Wide Web
Authors: Marrón David González , Ramírez Verónica Paola Corona , Zuñiga Juan Alejandro Arrieta , Pérez Roberto Hernández
Published: January 2024

In this computer's era, characterized by the rapid proliferation of indexed documents across the World Wide Web, the imperative arises for the employment of diverse strategies to enhance the positioning of websites within search engines, including but not limited to Google, Yahoo, and Bing. The voluminous expanse of indexed documents on the web, exceeding 30 billion, underscores the need for a systematic approach. This paper introduces the Search Engine Optimization (SEO) technique a method designed to elevate the inherent attributes of websites, facilitating superior evaluation and ranking by search engines, Notably, search engines incorporate over 200 distinct features within their ranking algorithms, encompassing internal factors inherent to developed websites and external factors predominantly associated with usage frequency. This paper details the series of activities related to the SEO technique, as well as the measurement results obtained before and after its application.
Genetic population structure of the pen shell Atrina pectinata along the coastlines of China revealed by microsatellites
Authors: Zhu Peican , Wang Fukai , Wu Biao , Wang Feng , Wang Chunde , Zhang Xiaotong , Yu Kai , Liu Bo
Published: January 2024

Background

An ecologically and economically important species in East Asia, the natural resources of pen shell Atrina pectinate have suffered severe population declines due to habitat destruction, pollution, and overfishing. Assessing genetic diversity and population structure is the basis for establishing conservation programs for A. pectinate.

Results

Our data indicated that high genetic diversity was found in all six populations, with mean allelic richness (Ar) ranging from 8.255 to 9.734, mean observed heterozygosity (Ho) from 0.574 to 0.680, and mean expected heterozygosity (He) from 0.620 to 0.691. The five A. pectinate populations were divided into two clusters. This clustering result was partly consistent with their geographical origin; the RZ population did not cluster with the northern populations (DL, CD), suggesting that there is no genetic divergence and geographical differentiation between the North China Sea (CD, DL, and RZ) and the Southeast China Sea (HK and ST).

Conclusion

Our results show no significant genetic differentiation between samples from the North China Sea and the Southeast China Sea. High dispersal potential of larvae by passive drift with ocean currents may explain the lack of genetic differentiation between samples. The results suggest a weak level of genetic structure in A. pectinate with a long planktonic larval stage.
Combined Effects of Drought and Low Temperature on Germination and Seedling Growth of Melon Cultivars
Authors: KAYA Gamze
Published: January 2024

The study aimed to determine the effects of drought (0.0, -2.0, -4.0, and -6.0 bar PEG 6000) and low temperature (18°C) on the germination and early seedling growth of three melon cultivars (Kırkağaç 589, Hasanbey 1, and Toros Sarıbal). Germination percentage, mean germination time, germination index, root length, shoot length, fresh and dry weight of the seedling, and vigor index of the melon cultivars were investigated. The results showed significant effects of low temperature and drought stress on the germination and seedling growth of melon cultivars. As temperature decreased and drought increased, the germination percentage decreased, and mean germination time was delayed. Drought stress led to a decrease in germination percentage, index, and all investigated seedling growth parameters, while the response of melon cultivars to drought stress varied. Seedling growth was more affected by low temperature than germination. Low temperature decreased germination percentage from 87.2% to 63.7% and seedling fresh weight from 140 mg/plant to 64 mg/plant. Each increase in drought levels resulted in a decrease in germination and seedling growth parameters of melon cultivars. Any seedling growth was not observed in Hasanbey 1 and Toros Sarıbal at -6.0 bar at 18°C. Melon cultivars showed different levels of tolerance to drought stress during germination and seedling growth stages, while they could maintain it up to -4.0 bar. It was concluded that Kırkağaç 589 germinated and grew better under drought stress at both optimum and low temperatures.
Proposed Marketing Strategy of Healthcare IVD Distributor Post Covid 19 Pandemic (Case Study of PT. Sinergy Diagnostic)
Authors:   School of Business and Management, Institut Teknologi Bandung, Indonesia, Mulya Mirza Khoerun Furqon , Aprianingsih Atik ,   School of Business and Management, Institut Teknologi Bandung, Indonesia
Published: January 2024

With the passage of time and the enhancement of societal well-being, there has been an increasing demand for health services within the community. The COVID-19 pandemic has had a profound effect on worldwide health systems and has caused a substantial overhaul in the healthcare industry. PT. Sinergy Diagnostic has been a distributor of In Vitro Diagnostics (IVD) for over 17 years and has catered to several clients. These establishments encompass medical laboratories, clinics, hospitals, and public institutions that are owned by both private and government entities effectively demonstrates the strategic implementation of Operation Cooperation (KSO). Amidst the pandemic, the company witnessed a significant surge in sales of Point of Care Testing (POCT), which can be attributed to the increased demand for quick diagnostic testing. Nevertheless, since the epidemic has concluded, the need for POCT is expected to decrease, presenting a potential threat to the company’s sales revenue, which became increasingly dependent on this category throughout the pandemic period. PT Sinergy Diagnostic must reassess its business plan and adjust to the evolving market conditions in order to maintain its company performance. For solving the problem, this study utilize a mixed research methodology, internally assesses PT Sinergy Diagnostic’s market position and operational capabilities through the application of the STP Analysis, Marketing Mix 7Ps, and the VRIO Analysis. For external, customer analysis conducted using interview method involved a total of 15 respondents and analysis of the data using descriptive statistical methods.
Health Claims in Food Products: Buyers Attitude and Behaviour in Indonesia
Authors:   School of Business Management, Institut Teknologi Bandung, Indonesia, Wangsaatmaja Addina , Sunitiyoso Yos ,   School of Business Management, Institut Teknologi Bandung, Indonesia
Published: January 2024

This study explores the dynamics of health claims in food products and investigates the attitudes and behaviors of buyers in Indonesia. With a growing global trend towards healthier lifestyles, understanding consumer responses to health-related claims on food items is crucial. The research delves into the factors influencing buyer attitudes, examining the impact of demographic variables, socio-cultural nuances, and individual attitudes towards health claims. Through a combination of qualitative and quantitative methodologies, the study aims to unveil patterns in consumer decision-making processes and discern the extent to which health claims influence purchasing behaviors in the Indonesian market. By shedding light on the intricate interplay between health claims and consumer choices, this research contributes valuable insights for both the food industry and policymakers seeking to foster healthier dietary practices in Indonesia.
Sistem Informasi Kepegawaian Berbasis Web Studi Kasus PT. Hara Sentosa Mandiri
Authors: Pamungkas Panji Putra , Danny Muhtajuddin , Muhidin Asep
Published: January 2024

Human Resource Information System (HRIS) is a very important system in an organization or institution, which aims to manage employee data, employee attendance, employee salaries, and so on. However, at present there are still many organizations or institutions that still use traditional systems. PT. Hara Mandiri Sentosa is one of the private companies that has not adopted an integrated human resource information system, such as using employee data with books, attendance filled in in writing by employees, and salary calculations that are summarized through the attendance so that they are prone to errors in the process. This research aims to build a web-based human resource information system using the waterfall method. The results of this study indicate that the system that was built can overcome the risk of errors in the process. This system is able to make the processing of human resource data more efficient and data security guaranteed.
Aplikasi Pencatatan Keuangan Berbasis Website Dengan Metode Rapid Application Development Pada PT Samsriwi Adi Megah
Authors: Apisca Dhea , Surojudin Nurhadi , . Edora
Published: January 2024

In an increasingly competitive and rapidly changing business world, keeping company finances organized and transparent is key to success. The website-based financial recording application comes as a modern solution that provides convenience and efficiency in managing the Company's finances. PT Samsriwi Adi Megah is one of the garment companies. It was found that financial record management still relies on the Microsoft Office Excel application so that it experiences searching for data within a certain period of time. This is because financial data is stored in many Excel worksheets or separate files. To overcome these problems, companies need to develop a website-based financial recording application with the rapid application development method. With an integrated system, the Company can accelerate the data processing process, facilitate report making and improve the right decision making.  The application of financial recording applications can improve the efficiency of PT Samsriwi Adi Megah's financial data processing and provide accurate and fast information.
Efeito da variação de temperatura no bacterioma do intestino médio de Aedes aegypti e seu impacto na modulação da digestão de sangue
Authors:   , Profeta Camila Aparecida
Published: January 2024

Sabe-se que a temperatura desempenha um papel na resistência/suscetibilidade dos mosquitos a infecções por patógenos, e em vários sistemas foi verificado um fenótipo resistente a baixas temperaturas. Estudos recentes mostraram que as bactérias do intestino médio parecem estimular o sistema imunológico do mosquito e, indiretamente, aumentar a proteção contra patógenos invasores. Em insetos hematófagos, não está claro como o repasto sanguíneo e a variação da temperatura ambiental afetam o bacterioma do inseto hospedeiro. Esse conhecimento é fundamental para compreender o impacto da temperatura na fisiologia do mosquito, a fim de buscar novas perspectivas de controle. Neste estudo, foram realizados experimentos no bacterioma intacto e reduzido para investigar a contribuição das bactérias intestinais na taxa de digestão do sangue em diferentes temperaturas (20, 28 e 36°C). Primeiramente, um coquetel de antibióticos (300 μg/ml) foi administrado às fêmeas do mosquito Aedes aegypti por 48 horas. Depois os mosquitos foram alimentados com sangue de camundongo e expostos às três temperaturas. O intestino médio foi dissecado 24 horas e 48 horas após a alimentação (ABF). Para obter taxas de digestão de proteínas em cada temperatura, foram determinados o conteúdo total de proteína e albumina, bem como a atividade de tripsina. Finalmente, para analisar as alterações na expressão gênica envolvida na resposta ao bacterioma intacto e reduzido, o RNA total foi extraído do intestino médio, dissecado 24 horas após a alimentação sanguínea, utilizando o RNeasy Mini Kit seguindo as instruções do fabricante. Nossos resultados demonstram que em um ambiente intestinal com carga bacteriana reduzida há menor teor de proteína e atividade enzimática a 28 e 36°C 24 horas após a alimentação sanguínea, demonstrando que o efeito da temperatura na digestão sanguínea depende do bacterioma intestinal. Além disso, a redução da carga bacteriana impactou na expressão dos transcritos, o que acarretou diminuição e aumento na expressão dos genes envolvidos na digestão sanguínea em 24 (ABF) nas três temperaturas. Embora sejam necessárias mais investigações para determinar os mecanismos moleculares destes processos, os nossos resultados indicam que a redução da carga bacteriana combinada com a variação da temperatura afeta a digestão sanguínea, bem como a expressão gênica associada a estes processos, o que por sua vez afeta a competência do vector. Palavras chaves: Aedes aegypti; temperatura; digestão do sangue; bacterioma intestinal; processos fisiológicos.
Lack of small business participation (small fishing companies SIC Code 13100) in the Transport Education Training Authority-Supported Schemes
Authors: Alexander Malcolm
Published: January 2024

The study focusses on the transport sector, where company participation level is measured at approximately 20% of levy paying enterprises, and this level is mostly based on relatively high levels of participation from large and medium-sized companies. The study explores the relationship between Sector Education and Training Authorities (SETAs) and the companies within the sectors they are mandated to serve by researching the Transport Education Training Authority (TETA) maritime subsector. The research focus is on small companies and the focus is specifically on the low rate of participation of smaller entities in the skills development landscape. The consequences of the lack of participation are investigated and the study concludes that the SETA’s ability to effectively research its sector skills, as well as the SETAs ability to provide effective skills planning in support of the national agenda, are both negatively affected by current levels of poor participation. The research was conducted on small fishing companies registered with TETA, in order to determine the reasons for low participation in the government’s mandatory grant scheme. The research is survey-based across participating and non-participating small companies. In addition, it is proposed that the elements contained herein are transferable to other subsectors of the transport economy (e.g. air, road and rail), and to the multitude of other SETAs that have small companies registered with them. Succinctly, there is no financial incentive to a small company to participate, the SETAs should consider incentives schemes to increase participation that is project-based and allows for subsidised training. The value of an improved Sector Skills Plan (SSP) that matches the skills needs of the sector increases the likelihood of projects having a meaningful impact on the sector and reduces fruitless and wasteful expenditure in the sector. The small business environment has huge potential to assist in skills development, a skilled workforce, improved productivity and reducing unemployment. The findings and solutions are important tools for taking the maritime development agenda forward.
Modern shipping needs to be cybersecure: A South African perspective
Authors: von Solms Rossouw , von Solms Suné
Published: January 2024

The traditional standalone operational technology systems that control multiple mechanical systems on board a ship get increasingly integrated with modern information and communications technology (ICT)-related systems. These ICT systems that continuously become interconnected with operational technologies and systems include the Internet-of-Things (IoT), autonomous technologies and the internet with adequate bandwidth etc. The IoT typically employs numerous sensors and captures vast amounts of data, which is processed, transmitted and turned into trusted intelligence to the advantage of all parties involved. Furthermore, modern navigational systems utilise global positioning systems (GPS), radar, sonar and computerised maps. These are used in conjunction with modern communication systems to communicate related data used for accurate navigation. In addition, autonomous technologies are highly dependent on accurate data communicated to them. Thus, it is clear that data is rightly termed ‘the new gold’ in the shipping industry. On the other hand, the maritime industry, like most other industries, is highly vulnerable to cybersecurity attack. As more data is captured, processed and communicated for the more critical shipping activities, the more vulnerable the industry will become to modern cybersecurity threats. Therefore, the interfaces between sensors, devices and different technologies, and the communication of captured data need to be properly secured. Furthermore, many of the shipping industry staff working with technologies where data are captured and communicated need to be educated on how to assist in securing this data. This paper will emphasise the continued use of ICTrelated systems in the shipping industry, and how this digitalisation and smart use of ICT solutions will benefit the maritime industry. In light of this, the purpose of this paper is to highlight the continued vulnerabilities to modern cybersecurity threats, and to discuss some solutions to securing these technologies towards securing the industry as a whole. The paper will also address aspects of educating maritime staff in technology-related areas ranging from the ICT- and cybersecurity-related topics that need to be included in maritime curricula, on the more formal side, to making all staff members more cybersecurity aware, on the more informal side.
Mosquito Control, Killing Them Before They Hatch
Authors:   School of Liberal Art, University of St. Thomas of Houston, Houston, USA, Tran Phi
Published: January 2024

Mosquitoes are the most harmful insects who cause 2 million illnesses, kill 28 thousand people daily, most of them are in underdevelopment countries where a good part of the population is living without running water, people store water in large containers for their daily uses especially for food preparation, cooking, and drinking; there come mosquito habitats. People there are looking up to science for uncharm methods to kill those mosquito-to-be larvae and pupae that are already in their home. Proposed methods include introductions of oil, soap, toxin, or larvae eating fish contaminate their waters making them unfit for human consumption, they do not welcome. Because the insects are naturally air breathers, using minuscule snorkeling syphons, the experiments used CO2 to suffocate them by bending a duct to redirect smog from small candles onto the water surface. As the result, they were all killed in minutes.
Hybrid Model for Improved Heart Disease Prediction
Authors:   Independent Researcher, Avon, Indiana, USA, Khankhoje Rohit
Published: January 2024

Cardiovascular disease, which encompasses various conditions affecting the heart and blood vessels, is a significant global health concern and a primary cause of mortality on a global scale. These ailments have a profound impact on heart function, blood circulation, and overall well-being. This investigation introduces a novel hybrid model that effectively combines the strengths of Decision Tree (DT), Logistic Regression (LR), and Artificial Neural Network (ANN) algorithms, thereby significantly augmenting the accuracy of heart disease prediction. The model demonstrates exceptional performance, boasting an impressive accuracy rate of 88%, which surpasses the individual accuracies of DT at 99%, LR at 80%, and ANN at 86%. Furthermore, the hybrid approach excels in precision, recall, and F1-score metrics, thereby substantiating its reliability and robustness as a predictive tool for heart disease. This research underscores the advantages of incorporating multiple algorithms in order to create a more efficient predictive model for cardiovascular health diagnostics.
Strategic Technical Debt Management: An In-depth Analysis of its Consequences and Mitigation Strategies in the Financial Industry
Authors:   Senior Advisor, Fiserv, United States, Mooghala Sridhar
Published: January 2024

This research looks into the important area of "Strategic Technical Debt Management" in software programs and shows how it has big effects on the complicated financial industry. This paper also takes a close look at how technical debt affects the quality, maintainability, and speed of software, focusing on how it affects economic systems. Adding graphs, tables, charts, and pictures to a story makes it better by making complicated ideas easier to understand. Real-life case studies from the banking sector give us concrete information and show us more effective methods. This paper is meant to make a big contribution to the conversation about strategic technical debt. It is aimed at both practitioners and academics and will be published in reputable journals.
DIGITAL PLATFORMS IN IMPROVING THE ACTIVITIES OF AGRICULTURAL COOPERATION
Authors:   Chelyabinsk State University, Abilova Ekaterina V.
Published: January 2024

The digital transformation of the agricultural industry can lead to a «gap» between small forms of agricultural business and large agricultural holdings due to various conditions and characteristics of agricultural production. The article analyzes digital services used in agriculture, considers the benefits of digital transformation for farms and agricultural cooperatives, and proposes a model of a digital platform for small forms of agricultural business.
INTELLIGENT ROBOTIC TECHNOLOGIES AND THEIR ANALYSIS
Authors:   Ural State Economic University, Rozhkov Evgeniy V.
Published: January 2024

The article is devoted to the study of processes associated with the possibility of using robotic technologies and analysis in the economy. The study is aimed at conducting a preliminary analysis of the use of robotic technologies. The methodological base of the research includes empirical methods of analysis and synthesis, descriptions, etc. The author’s work showed the need to determine the capabilities of robotic technologies at the scientific level. Examples of the use of robotic technologies and analysis are given. The author publishes a number of articles on the topic of digitalization in the economy of the city and the region.
INNOVATIVE SYSTEMS FOR MANAGEMENT DECISION SUPPORT: ANALYSIS AND APPLICATION OF EXISTING SYSTEMS
Authors:   Grozny State Oil Technical University named after Academician M.D. Millionshchikov, Suleymanova Leila O. , Tavbulatova Zulai K. ,   Chechen State University, Magomaeva Leila R. ,   Grozny State Oil Technical University named after Academician M.D. Millionshchikov
Published: January 2024

In this scientific article, the analysis, development and application of innovative management decision support systems was carried out. Various systems were reviewed such as SAP Business Objects, IBM Cognos, Oracle Business Intelligence and ITSM 365. Each system was analyzed against a number of criteria such as data analytics capabilities, usability, performance and price. As a result, the advantages and disadvantages of each system were identified, which helped to determine their effectiveness and suitability for use in enterprises. It was found that the development and implementation of management decision support systems can face difficulties, such as the high cost of development, the need to take into account the specifics of each individual organization and business processes, as well as the complexity of implementing and training staff.
Evaluation of Caspase-8 Level in Serum of Patients with Autoimmune Thyroid Disorders
Authors: Albadri Mohammed , Nasser Issam Jumaa , Ali A.A Mahdi
Published: January 2024

Autoimmune thyroid diseases (AITDs), including Graves' disease and Hashimoto's thyroiditis, are characterized by lymphocytic infiltration of the thyroid and the production of thyroid autoantibodies. While the etiology of AITDs is still not fully understood, a combination of genetic susceptibility and environmental triggers is believed to contribute to the breakdown in immune tolerance. This study aimed to evaluate the levels of thyroid hormones (T3, T4, TSH), Anti-thyroid peroxidase Abs (Anti-TPO Abs), Anti-Thyroglobulin Abs (Anti-TG(, and apoptosis marker (Caspase-8 ) in Iraqi patients with AITDs compared to healthy controls.
              A total of 1000 patients participated in the study 820 were excluded from the study because it was non-immune thyroid disease, and 180 subjects were recruited, including 60 Graves’ disease patients, 60 HT patients, and 60 healthy controls. Serum levels of T3, T4, TSH, Anti-TPO Abs and Anti-TG, caspase 8, and inhibin were measured. T3 and T4 levels were significantly decreased in Hashimoto's thyroiditis patients and increased in Graves’ disease patients compared to controls. TSH was significantly elevated in Hashimoto's thyroiditis and reduced in Graves’ disease patients. Caspase-8 was significantly higher in Hashimoto's groups compared with the control group, and Significantly lower in Graves group compared with the control group.
In conclusion, an altered balance in thyroid hormones, Anti-TPO Abs, Anti-TG, and apoptosis markers occurs in AITDs. Elevated caspase-8 suggests that increased apoptosis may contribute to thyroid damage in AITDs. Further research is needed to clarify the roles of these mediators in AITD pathogenesis.
Locational and Seasonal Bioaccumulation of Heavy Metals in Bivalves Sinanodonta woodiana and Unio tigridis from the Al-massab alam River, Thi-qar province
Authors: M. Al-taher Qasim
Published: January 2024

The aim of this research was to measure and compare the contents of three elements  (chromium, uranium, and aluminum) in water, sediments, and oysters (Unio tigridis and Sinanodonta woodiana) from three stations in different seasons. The results showed that the concentration of these elements varied widely while exhibiting some trends and patterns. Chromium had very low concentration in water as well as oysters yet there was an increase in sediments during winter until autumn. Uranium had low concentrations in water plus oysters however its concentration increased significantly during summer including autumn season in water as well as sediments. Aluminum exhibited wide variations among stations and seasons with no clear trend or pattern both in water, sediments and oysters. Several factors might have caused variations of these elements such as; natural geochemical background, anthropogenic activities, hydrological conditions, biological processes and analytical methods used. It is therefore necessary to conduct more research on these variations so that their causes could be identified as well as their effects while assessing the potential ecologic impacts plus human health risks within the study area.
PENGARUH KEMASAN DAN ORIENTASI PASAR TERHADAP KEPUASAN KONSUMEN TEH BOTOL SOSRO DI KECAMATAN MEUREUDU KABUPATEN PIDIE JAYA
Authors: Muammar Muammar , Ismayli Ismayli , Isnaini T
Published: January 2024

ABSTRAKTujuan penelitian ini untuk mengetahui Pengaruh Kemasan dan Orientasi Pasar Terhadap Keputusan Pembelian Teh Botol Sosro di Kecamatan Meureudu Kabupaten Pidie Jaya. Sampel penelitian ini 100 orang responden, data dikumpulkan dengan kuesioner, analisis data menggunakan regresi linier berganda. Hasil penelitian diperoleh nilai koefisien korelasi (R) sebesar 87,3% dapat memberikan pengertian ada hubungan antara faktor kemasan (X1), dan faktor oreintasi pasar (X2), dengan kepuasan konsumen (Y). Semakin tingginya nilai yang diperoleh maka semakin erat pula hubungan antara variabel independen dengan variabel dependen, artinya semakin erat pula hubungan antara kemasan dan orientasi pasar memiliki hubungan yang erat dengan kepuasan konsumen dengan nilai sebesar 87,3% dalam katagori hubungan yang kuat. Nilai koefisien diterminasi (R2) adalah sebesar 76,3% dapat memberikan pengertian ada pengaruh yang signifikan antara faktor kemasan dan orientasi pasar dengan kepuasan konsumen.
Nanotechnology and Its Impact on Physical Sciences
Authors: Madjozi Monica
Published: January 2024

Purpose: The main objective of this study was to explore nanotechnology and its impact on physical sciences.

Methodology: The study adopted a desktop research methodology. Desk research refers to secondary data or that which can be collected without fieldwork. Desk research is basically involved in collecting data from existing resources hence it is often considered a low cost technique as compared to field research, as the main cost is involved in executive’s time, telephone charges and directories. Thus, the study relied on already published studies, reports and statistics. This secondary data was easily accessed through the online journals and library.

Findings: The findings revealed that there exists a contextual and methodological gap relating to nanotechnology and its impact on physical sciences. Preliminary empirical review revealed that nanotechnology has significantly transformed physical sciences, particularly in physics, chemistry, materials science, and condensed matter physics. It has facilitated the development of novel materials and devices, enabling advancements in quantum technologies and nanoelectronics. Interdisciplinary collaboration is key, emphasizing the need for researchers from diverse scientific backgrounds to work together to harness nanotechnology's full potential. Additionally, the study underscores the importance of ongoing research to address ethical, safety, and environmental concerns associated with nanotechnology, ensuring its sustainable integration into physical sciences.

Unique Contribution to Theory, Practice and Policy: The Quantum Confinement Theory, Materials Science and Nanomaterials Theory and the Interdisciplinary Collaboration Theory may be used to anchor future studies on nanotechnology. The recommendations stemming from the study advocated for fostering interdisciplinary collaboration among researchers, investing in nanoscience education, promoting ethical and responsible research practices, and supporting long-term environmental assessments. These suggestions aim to facilitate the seamless integration of nanotechnology into the physical sciences, ensuring that it leads to innovative breakthroughs while addressing ethical, safety, and environmental considerations.
Apoptotic and Autophagic Cell Death Effects of the Hexane Extract of Tropical Marine Algae Halymenia durvillei against Human Glioblastoma Cells: In vitro and in silico Studies
Authors: Vivithanaporn Pornpun , Siangcham Tanapan , Tanawoot Varitta , Settacomkul Rapeewan , Pranweerapaiboon Kanta , Meemon Krai , Niamnont Nakorn , Tamtin Montakan , Sobhon Prasert , Sangpairoj Kant
Published: January 2024

Glioblastoma (GBM) considered as aggressive brain cancer with high mortality rate in patients even after surgical resection. Resistant to chemotherapy is the major problem in GBM therapy. Discovery of novel bioactive compounds from algae is being investigated as alternative sources for potential treatment as well as prevention in glioblastoma. This study revealed the effects of marine red algae extract from hexane solvent fraction of Halymenia durvillei (HDHE) on proliferation and cell death in A172 human GBM cells. HDHE decreased proliferation and promoted cell cycle arrest at G2/M phase. HDHE induced apoptotic cell death in A172 cells through mitochondrial membrane dysfunction, the decrease of anti-apoptotic Bcl-2 protein expression, and activation of caspase 3/7. Moreover, HDHE increased intracellular reactive oxygen species (ROS) production and accumulation of LC3-II, an autophagic marker. The docked conformation of palmitic acid, a major component of HDHE, showed a high affinity binding to TP53 and Beclin-1 as cell death-related target molecules. This research conclusively demonstrated that HDHE might serve as a potent anticancer agent against glioblastoma by promoting apoptotic and autophagic cell death in A172 human GBM cells.
HIGHLIGHTS

The palmitic acid-enriched extract of red alga Halymenia durvillei (HDHE) could inhibit proliferation of A172 human glioblastoma cells by arresting cell cycle at G2/M phase
HDHE could induce both caspase-dependent apoptotic and autophagic death of A172 cells
Palmitic acid, a major component of HDHE, showed a high affinity binding to TP53 and Beclin-1
The extract could be beneficial to develop as chemopreventive agents or food supplements against glioblastoma

GRAPHICAL ABSTRACT
Medicina estética y paciente oncológico. Una interacción posible y deseable
Authors: Esteban Herrero Margarita
Published: January 2024

La línea entre belleza y salud es extremadamente fina. La interacción entre la medicina estética y la oncología supone un papel más relevante en diagnosticar, prevenir, preservar y mejorar el deterioro físico y psicosomático al que puede verse sometido un paciente oncológico, sea por su enfermedad de base o por el tratamiento de esta.
Generación Z: desafíos para la educación superior en el nuevo milenio
Authors: Collantes G. Rubén D. , Jerkovic Maricsa
Published: January 2024

La Generación Z (Gen Z), son personas nacidas después del año 2000. Algunos critican la manera en la que la Gen Z se desenvuelve, al ser intolerantes y explícitos al expresarse; pero también se reconoce su dominio tecnológico. El presente trabajo reflexiona sobre la Gen Z y cómo hacen frente estos jóvenes a los desafíos de la educación superior en el nuevo milenio. Para ello, los autores analizaron 30 trabajos de especialistas, en complemento con su experiencia docente en años recientes. De acuerdo con el análisis, la Gen Z ha tenido contacto con las tecnologías de información y comunicación (TIC) desde que nacieron, por lo que su interacción social se apoya en estos medios, facilitando el proceso enseñanza-aprendizaje durante la pandemia por COVID-19. Sin embargo, son considerados muy sensibles a la crítica, realizan el esfuerzo mínimo para cumplir con lo solicitado, les cuesta analizar, interpretar y generar contenido original, desarrollan más competencias blandas, pero requieren fortalecer competencias duras necesarias frente a nuevos retos en este milenio. En conclusión, la Gen Z posee intereses diferentes a las generaciones previas, pero con potencial de aprender y desarrollarse como individuos competentes y completos, mediante una buena guía e instrucción por parte del docente.
Interculturalidad: un cambio de perspectiva en la educación
Authors: Portillo Wilches Jorge Camilo
Published: January 2024

El presente escrito tiene como objetivo indagar acerca de los aspectos más relevantes de la interculturalidad en el ámbito educativo, con el ánimo de brindar insumos que contribuyan en la construcción de un discurso epistémico que fundamente la práctica docente. A partir de una revisión documental se hace el análisis a la interculturalidad desde sus definiciones, orígenes, características, enfoques, metas, críticas y perspectivas emergentes en educación. Se concluye que: la interculturalidad tiene múltiples definiciones que evidencian la complejidad del concepto; su origen se remonta a la educación y las luchas de los pueblos indígenas; una educación intercultural es reflexiva, sistémica, equitativa, inclusiva, integral, justa, transformadora y universal. Entre los enfoques sobresale el de corte crítico, que busca hacer frente a la educación totalizadora, la principal meta es impulsar una pedagogía abierta al diálogo y coherente con las condiciones de los estudiantes. La crítica recae sobre el plano metodológico, sustentada en las incoherencias entre los discursos institucionales y las prácticas docentes. Por último, se plantean como perspectivas emergentes la construcción de nuevas bases conceptuales y metodológicas y las innovaciones en el proceso de formación docente para que la interculturalidad se viva realmente en las aulas de clase.
Identidad nacional y literatura panameña para niños y jóvenes en los planes y programas de estudio de Español en la etapa primaria del nivel de Educación Básica General de Panamá
Authors: Changmarín Romero Abril
Published: January 2024

El estudio se dirige a determinar la incorporación de la literatura infantil y juvenil de autores panameños en los planes y programas de estudio de la asignatura de Español de la educación primaria en Panamá, como medio por excelencia para la formación de la identidad nacional y cultural.  Para tal propósito se utilizó una metodología de tipo analítica-descriptiva   y el estudio de fuentes documentales y bibliográficas de interés.

Del trabajo se concluye que, aunque desde la instancia Constitucional y de la Ley 47 Orgánica de Educación se establece la formación de la identidad nacional como una de las finalidades y objetivos del sistema educativo, se observa una ruptura de tales intencionalidades debido a imprecisiones y omisiones en los programas de Español.

Por la importancia de los planes y programas curriculares como instrumentos orientadores del proceso de enseñanza-aprendizaje a nivel nacional, se advierte la necesidad de un replanteamiento de éstos, para fortalecer la formación de la identidad nacional y cultural mediante la lectura, apreciación, valoración y expresión creativa de obras de autores panameños de literatura infantil y juvenil.
Percepción de los estudiantes de psicología sobre la asignatura Psicología Industrial de la Universidad de Panamá
Authors: Córdoba-García Nancy , Arosemena Amy , Santos Figueroa Eloy Melvin
Published: January 2024

Los psicólogos industriales se especializan en analizar el comportamiento humano en el lugar de trabajo, utilizando sus conocimientos para mejorar aspectos como la productividad, la satisfacción laboral, el liderazgo, la selección y capacitación de personal. Considerando la importancia de esta disciplina, se llevó a cabo un estudio para determinar la percepción de los estudiantes de psicología respecto a la asignatura de Psicología industrial. Esta investigación se realizó en la facultad de Psicología en el campus Harmodio Arias Madrid de la Universidad de Panamá, se tomaron 75 estudiantes de IV y V año de la licenciatura, seleccionándose una muestra de conveniencia de 45 personas. El estudio se enmarcó en el paradigma cualitativo y tuvo un enfoque descriptivo cuantitativo de corte transversal, utilizando un diseño no experimental.  Para registrar las valoraciones cualitativas, se utilizó la encuesta y la recopilación de los datos se utilizó un cuestionario diseñado específicamente para cumplir con el objetivo del estudio. Los resultados obtenidos revelaron que la mayoría de los encuestados considera la asignatura relevante y útil para su futura carrera profesional. Sin embargo, existen opiniones divididas en cuanto al nivel de interés, motivación y aplicación práctica de los conocimientos adquiridos en la asignatura. Estos hallazgos proporcionan una visión integral sobre cómo los estudiantes perciben y valoran la psicología industrial en el contexto de su formación académica y futura trayectoria profesional.
Primary Care - A brief summary that every Cephaliatrist should know
Authors: Ribeiro Fernanda Cristina Poscai , Pereira Kleber Fernando , César Âlcantara Ramos de Assis
Published: January 2024

Introduction
Primary Health Care (PHC) serves as the foundation of the healthcare system, playing a vital role in disease prevention, treatment, and health promotion. It functions as the first point of contact between patients and the healthcare system, offering comprehensive and continuous care.
Objectives
The primary objective of this review is to provide an in-depth understanding of PHC, with a focus on its structure, processes, services, and projects, as a basis for potential initiatives related to headache disorders.
Methodology
The literature review encompassed various sources, including Google Scholar, Scielo, Pubmed/Medline, Lilacs, and government sources. Keywords related to PHC, including topics such as structure, functioning, and services, as well as specific areas like Women's Health, Mental Health, vaccination, and child healthcare, were employed.
Results
PHC is responsible for coordinating the Regionalized Healthcare Network (RAS), which includes Primary Care, communication centers, secondary and tertiary care points, support systems, and governance. PHC serves as the gateway, providing various services, including women's health, mental health, vaccination, child healthcare, and various other medical services. Furthermore, teams, such as the Family Health Strategy and the Family Health Support Center, play distinct roles in health promotion and care coordination. The focus of PHC includes territorialization, vaccination, wound care, women's health, and child healthcare, with a commitment to interventions and projects aimed at improving the quality of care and achieving positive outcomes.
Conclusion
PHC can play a crucial role in addressing headache disorders, offering early diagnosis, appropriate management, and the promotion of healthy habits. Investing in programs and professional training within PHC can be essential to provide effective care and reduce the demand for emergency care in cases of headache disorders.
Perceção do conhecimento e implementação da Classificação Internacional de Funcionalidade (CIF) da Organização Mundial de Saúde (OMS) pelos profissionais de saúde
Authors: Jacobsohn Lia , Neves Maria Ana
Published: January 2024

Introdução: A CIF é uma das classificações internacionais elaborada pela OMS, passível de ser aplicada em diversos aspetos da saúde e de traçar um perfil de funcionalidade da pessoa. Visa facilitar a interdisciplinaridade, unificar a comunicação entre os profissionais de saúde e estruturar os processos de avaliação, universalizando a forma de apresentação de resultados (WHO, 2001). A literatura atual tende a ser parca e divergente no que respeita a objetivos de investigação e opções metodológicas, o que suscita dúvidas e torna urgente perceber as limitações sobre o conhecimento e implementação da CIF na prática clínica dos profissionais de saúde. Objetivos: Pretende-se desenvolver uma revisão de escopo para explorar a produção científica sobre o conhecimento e perceção dos profissionais de saúde sobre a CIF e a sua implementação na prática clínica. Material e Métodos: Estudo não experimental, descritivo, pesquisa na PubMed com as palavras-chave: ICF; Health Professionals; Knowledge; Perception; artigos na área das ciências da Saúde sobre o conhecimento ou perceção ou implementação da CIF. Resultados: Através da revisão de escopo para os outcomes apresentados foram identificados 26 artigos, demonstrando a escassez de informação sobre o tema. Os profissionais de reabilitação são os que mais utilizam a CIF, sendo a maioria dos estudos da medicina de reabilitação. Alguns autores referem não encontrar estudos sobre o perfil de conhecimento da CIF em médicos e enfermeiros, sugerindo uma heterogeneidade no conhecimento entre os diferentes profissionais de saúde. No entanto, é possível encontrar estudos em contextos mais específicos, como o conhecimento sobre Core Sets, em médicos, enfermeiros, fisioterapeutas e terapeutas ocupacionais. Há estudos que identificam diferentes níveis de conhecimento e aplicação da CIF na prática profissional nas diferentes partes do mundo, sugerindo recomendações e soluções para estas disparidades. Os estudos existentes foram realizados e recolhem dados em diferentes países como Paquistão, Brasil, Israel, África do Sul, Suécia, Arabia Saudita. Conclusões: Apesar da escassa informação sobre a aplicabilidade da CIF na prática clínica dos profissionais de saúde, os Fisioterapeutas são uma das classes profissionais que mais se destaca no estudo e publicação sobre esta temática.