bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effectiveness of Using Picture and Picture Methods Through Storytelling in Improving Essay Writing Skills For Japanese Literature Study Program Students At Pakuan University
Authors: Karyati Alo , Rahmawati Yelni
Published: January 2023

This study discusses the effectiveness of using the picture and picture methode through storytelling ini improving the ability to write essay/sakubun in Japanesse Study Program students at Pakuan University. Composing or Sakubun is a person's ability to pour his thoughts into written form. In composing there are various methods, one of which is picture and picture. Picture and picture method is a learning model that uses pictures that are arranged and combined into an essay. Meanwhile, storytelling is the delivery of stories to listeners that are fun, not patronizing and can develop imagination. The formulation of the problem in this study, including: (1) can the picture and picture method through storytelling improve students' pocketbook writing skills? (2) How is the student's Sakubun writing ability after using the Picture and picture method through storytelling? (3) how is the students' writing ability after using the picture and picture method through storytelling. The purpose of this research is (1) to find out whether the picture and picture method through storytelling can improve students' pocketbook writing skills (2) to find out how students' pocketbook writing skills are after using the Picture and picture method through storytelling? (3) knowing how the students' pocketbook writing skills are after using the picture and picture method through storytelling. The method used in this research is pure experiment or true experiment. The population and sample in this study were the third semester students of the Japanese literature study program at Pakuan University as many as 22 people. The data analysis technique in this study used SPSS 16. The results of this study are expected to be useful for Japanese language learners throughout Indonesia, especially for learners who sakubun.
The Effects of Continuing Prostitution on Prostitution Women, Community Women, and Anti-prostitution Activists: Focused on Their Experiences in Wanwol-dong, Busan
Authors:   The Women’s Studies Center, Choi Su Yeon
Published: January 2023

In this study, the Busan Wanwol-dong the red light district, the first brothel in Korea, continues to this day under the connivance and management of the central and local governments. Laws and norms are inconsistent, ‘Wanwol-dong’ itself has a mixture of residential and commercial areas, or is closely connected, affecting the residents of the community. In this regard, I studied what the experience of the prostitution women, local community women, and anti-prostitution activists, who are directly victims of Wanwol-dong, by the continuation of the Wanwol-dong prostitution gathering place, and what the impact was depending on the location. To this end, 9 research participants who were closely related to the Busan Wanwol- dong the red light district were selected and conducted as a case study method. The research participants' experience of social control, masculine culture, and connivance and management, which are formal regulations, due to the continuation of the Busan Wanwol the red light district differs depending on the location of women, Prostitution women, community women, and anti- sex trafficking activists repeatedly practice femininity of the 'protected sex' and 'non-protected sex', and as they become gendered, they internalize double norms and become marginalized. However, anti-prostitution activists challenge patriarchal double norms and cause cracks in the empowerment of sex while eradicating prostitution and closing down the Wanwol-dong assembly point in Busan while supporting prostitution women. In addition, prostitution in a specific area spreads the conventional wisdom that prostitution is considered natural, and the demand for sex purchase increases. As it becomes insensitive to violence against women, it strengthens violence against women and puts them in an inferior position, deepening gender empowerment. The Busan Wanwol-dong the red light district is directly and indirectly connected to the local community, such as violence against women and illegal acts, as residential and commercial areas develop through acquiescence and management, which are formal regulations of the government and local governments. Indifference to or concealment of prostitution. In addition, as the system and norms in the local community are inconsistent with each other, the law does not play a role, which is the cause of the persistence of the Busan Wanwol-dong the red light district.
Capital Account Liberalization Debates
Authors: Singh Rimjhim
Published: January 2023

Abstract: The case for capital account liberalization has been the centre of outgoing debate. This paper discusses both the short term and longer term flows (FDI). This paper is divided into 5 sections. Section 1 presents the claims of neoclassical economists who believe that the case for free trade is the same as the case for capital account liberalization. They further point out that such liberalization increases social welfare and promotes efficiency. Section 2 provides the critique of the classical view as several assumptions made in traditional theory may not hold in real life. Section 3 provides the empirical evidence to claim that free capital flows lead to instability and culminate into a crisis. Section 4 explores the effects of FDI on countries and concludes that unrestricted flows may not always benefit nations. Section 5 analyses empirically the effect of FDI on inequality, long term and short term economic growth.
Performance of High-Strength Concrete Properties for Two Locally Available Aggregates: Partial Gradation Approaches
Authors: Pertiwi Dewi , Agusdini Theresia Maria Chandra , Komara Indra , Wahyu Ahmad
Published: January 2023

The aggregates in a concrete play a role in both strength and durability. Without a change of doubt, aggregates have a significant impact on mechanical, fresh and long-term performance properties of concrete. Low quality aggregates will give low behaviours that affect the condition of the concrete. In this investigation, improvement of local’s aggregate - natural mount sand and uncrushed mount gravel taken from Lumajang, Pasuran and Bangkalan, used as the parameter study. This study is conducted to support the low characteristics aggregate in terms of water absorption, sorptivity and compressive strength concrete. Three mixes variables are used based on w/c content, 0.40, 0.35 and 0.30 reflected the concrete quality. On the other hand, concrete mixes with locally grading group are 80 % aggregate from Bangkalan and 20 % aggregate from Lumajang or Pasuruan + Bangkalan (M4 and M5). The results indicated that the M4 and M5 grading group concrete mix had the maximum compressive strength out of the eight different concrete mixes. This particular mixture also improves the water absorption and sorptivity of the concrete.
HIGHLIGHTSTen concrete mixes with three concrete types were prepared using mount sand uncrushed mount gravel, with respect to understanding mechanical and physical properties comparing to 28-day compressive strength results. Those three mixes, M1, M2 and M3, provided to give the alternative of using unused coarse aggregate with low characteristic under three different w/c ratio i.e., 0.40, 0.35 and 0.30. Those conditions relate to the concrete quality - minimum compressive strength that normally used in the construction. Low characteristic aggregate, without a doubt impacting on long term performance properties of concrete structure. Locally available materials taken from Lumajang, Pasuruan and Bangkalan were used as the combined grading group of fine and coarse aggregate in each mixture. It was found that the optimum combine grading group was fine aggregate from Bangkalan + coarse aggregate from Lumajang or Pasuruan + Bangkalan (M4 and M5). Using M4 and M5 grading group, results indicated that, the highest compressive strength among the eight concrete mixes. In addition, these concrete mixes also illustrate to have low sportively and water absorption.
GRAPHICAL ABSTRACT
Osteogenesis imperfecta/Ehlers-Danlos overlap syndrome (COL1-related disorder) and pregnancy
Authors:   Department of Obstetrics and Gynecology, Faculty of Medicine, Palacky University and University Hospital Olomouc, Czech Republic, Šinská Alexandra , Hostinská Eliška , Pilka Radovan
Published: January 2023

Ehlers-Danlos syndrome is in a group of connective tissue disorders that can result in a range of complications during pregnancy. Clinical manifestations include skin hyperextensibility, atrophic scarring, poor wound healing, hyperflexibility or higher risk of organ ruptures (uterine rupture, aortal dissection). The combination of Ehlers-Danlos syndrome and osteogenesis imperfecta is very rare (< 1/1,000,000 according to Orphanet). We are presenting a case of woman with osteogenesis imperfecta/ Ehlers-Danlos overlap syndrome and her pregnancy complicated by aortal dilatation. Our case has attempted to highlight the potential obstetric complications and to attract the attention of clinical physicians to the rare but extremely dangerous syndrome. Key words: Ehlers-Danlos syndrome – osteogenesis imperfecta – COL1-related disorder – pregnancy – aortal dissection
Vulvar carcinoma and its recurrences – principles of surgical treatment
Authors:   Gynecological Oncology Center, Department of Obstetrics and Gynecology, Medical Faculty of Masaryk University and University Hospital Brno, Czech Republic, Viktora Libor , Minář Luboš , Felsinger Michal , Weinberger Vít
Published: January 2023

Objective: A comprehensive overview of the surgical treatment of vulvar cancer, including recurrent forms. Methodology: A review work providing a basic overview of the pathogenesis, dia gnosis and surgical treatment of vulvar cancer with a focus on the possibilities of treatment of its recurrences. It includes an illustrative case report presenting a patient with invasive squamous cell carcinoma of the vulva with iterative local recurrences and subsequent development of tumor triplicity and distant metastatic involvement. Conclusion: Surgical treatment remains the main modality of vulvar cancer therapy, even in the case of locally advanced or recurrent findings. In these cases, multidisciplinary cooperation of operational fields is necessary. The discipline of treated patients with participation in regular dispensary care plays an important role in the early detection of recurrences. (Chemo)radiotherapy remains a possible alternative to the surgical solution; in clinical practice, radiotherapy has an irreplaceable place in adjuvant therapy. Regional and distant recurrences are characterized by a poor prognosis. Key words: vulvar cancer – surgery – local recurrence – groin (inguinal) recurrence – distant recurrence – chemoradiotherapy
Pelvic packing in the treatment of severe postpartum posthysterectomiam hemorrhage
Authors:   University Department of Gynecology and Obstetrics, Clinical Hospital Sveti Duh Zagreb, Catholic University of Croatia Zagreb, Croatia, Habek Dubravko , Pavlović Goran , Cerovac Anis
Published: January 2023

Introduction: Pelvic packing (PP) as a simple method of ”damage control surgery” in severe abdominopelvic hemorrhage in gynecological and obstetric surgery after emergency obstetrics or gynecological hysterectomy. Objective: To present the case of successful PP as a simple and effective method in refractory pelvic bleeding after emergent peripartum hysterectomy and severe obstetric shock with consumptive coagulopathy. Case report: Acording to laboratory findings and clinical condition in a 30-year-old (G2 P2) parturient, it was most likely an obstetric embolism with uterine rupture as the cause of severe postparum hemorrhage with disseminated intravascular coagulopathy and obstetrics hemorrhagic shock development in the described case. Pelvic packing after postpartum hysterectomy was the definitive minimally invasive and simple hemostatic procedure. Conclusion: The use of pelvic packing and obstetrics skills should be included in the protocol as a necessary, life-saving, and uncomplicated vital indication procedure. Key words: postpartum hemorrhage – obstetrics shock – emergency postpartum hysterectomy – pelvic packing
Kıblenin Kâbe ye Çevrilmesiyle ilgili Rivâyetlerin Değerlendirilmesi
Authors: Özpınar Ömer
Published: January 2023

Kıblenin Beyt-i Makdis’ten Kâbe’ye çevrilmesine, kıblenin tahvîli denmektedir. Kıblenin çevrilmesiyle ilgili ‎rivâyetler, hadîs ve siyer kaynaklarında nakledilmektedir. Bu rivâyetler temelde üç hususta bilgi içermektedir. ‎Birincisi, tahvîl emrinin Hz. Peygamber’e nerede ve nasıl indiğidir. İkincisi, Kâbe’ye doğru kılınan ilk namazın ‎hangi namaz olduğu bilgisidir. Üçüncüsü, tahvîl haberi ulaştığında namazın geri kalanını Kâbe’ye doğru ‎tamamlayan iki kıbleli mescit halkının kimler olduğudur. Ancak hadîs ve siyer kaynaklarındaki bu rivâyetlerin ‎bir kısmı birbiriyle çelişmektedir. Dolayısıyla kıblenin tahvîlinin gerçekleşmesiyle ilgili farklı değerlendirmelere ‎yol açmaktadır. İşte bu makale, hadîs ve siyer kaynaklarındaki kıblenin tahvîliyle ilgili farklı ve çelişkili ‎rivâyetleri literatür taraması yöntemiyle tespit edip değerlendirmeyi amaçlamaktadır. Metot olarak hadîs ve ‎siyer kaynaklarındaki ilgili rivâyetler ayrı başlıklar altında ele alınıp rivâyet usulü ve bütünlük ilkesine göre ‎incelenmektedir. Böylece kıblenin tahvîliyle ilgili rivâyetler, kaynak ve muhteva farklılığına göre tespit edilmeye ‎ve akabinde bütünlük ilkesi bağlamında değerlendirilmeye çalışılmaktadır. ‎
İzzeddîn el-Haznevî nin Hayatı, İlmî ve Tasavvûfî Kişiliği
Authors: Az Ahmet
Published: January 2023

Bu çalışma 20. yüzyılda 1925-1992 yılları arasında yaşamış, Nakşbendî-Hâlidîliğin
bir kolu olan Haznevîliğin, Suriye başta olmak üzere ülkemizde ve birçok Avrupa
ülkesinde yayılmasında önemli katkıları olan İzzeddîn el-Haznevî’nin (öl.
1413/1992) hayatı, ilmî ve tasavvûfî kişiliği hakkındadır. Babası Ahmed elHaznevî’ye nisbetle Hazneviyye olarak anılan bu ekol, gerçek kimliğine İzzeddîn elHaznevî ile kavuşmuş, daha sonra talebeleri ve halifeleri sayesinde ilmî ve tasavvûfî
faaliyetler artarak devam etmiştir. Gerek ilmî gerek tasavvûfî yönüyle toplumun dinî
ve ictimaî hayatında derin izler bırakan İzzeddîn el-Haznevî, terbiye metodu ve
eğitimci kişiliğiyle de ön plana çıkmış dönemin önemli şahsiyetlerinden biridir.
Nitekim o, Hazneviyye dergâhının irşâd yöntemine eğitimsel bir perspektif
kazandırarak ulemâ kesiminin de takdirini kazanmayı başarmış ve toplumun dinî
konularda bilinçlenmesine kaynaklık etmiştir. İlim-irfân metodunun şeriata ittiba,
muhabbet, ihlas ve teslimiyet temelleri üzerine inşa edildiğini ifade eden İzzeddîn elHaznevî, özellikle siyasete ve siyasîlere karşı mesafeli tutumu ve kimseden maddi
yardım kabul etmemesiyle de dikkat çekmektedir. Binâenaleyh, bu çalışmada,
İzzeddîn el-Haznevî’nin hayatı, ilmî ve tasavvufî görüşlerinin yanı sıra, Haznevîliğin
doğup geliştiği Suriye’de onunla başlayan tecdit hareketini ve dergâhının ıslahat
çizgisini de ortaya koymaya çalışacağız
Kadının Emeğine ve Çalışma Hayatına Oku Dergisinden Bakmak
Authors: Taş Mustafa
Published: January 2023

Türkiye'de 1950’lerde iç göçle birlikte kırsaldan gelen ailelerin kızları okumaya, kadınları uzmanlık istemeyen işlerde çalışmaya başlayınca, bu durum, muhafazakârlar tarafından en çok tartışılan konulardan biri olmuştur. Bu çalışma, 1961 yılında yayın hayatına başlayıp 209 sayı çıktıktan sonra 1979 tarihinde kapanan, İslamın İlk Emri Oku dergisinde yayınlanan yazılarda, kadının çalışma hayatını incelemeyi amaçlamaktadır. Sosyal sorunlar çalışılırken, konuyu öncesi ve sonrası ile ele almak yarar sağlayabilir. Bu yüzden derginin yayın hayatı öncesi ve sonrasında kadının meslek hayatıyla ilgili kitap, dergi makale, film gibi çeşitli eserlerden faydalanılmıştır.
Genel olarak dergide bulunan yazılar akademik değildir. Günlük konuşma dilini kullanmışlar, bazen düşüncelerini organize etmede zorlanmışlardır. Konumuzla ilgili bir örnek vermek gerekirse, kadın, İslami şartları yerine getirirse çalışabilir dedikten birkaç paragraf sonra, kadının evinde oturması daha uygundur demişlerdir. Ayrıca yazıların çoğu bir tekrar niteliğindedir. Aynı konuyu belirli aralıklarla ele almalarına rağmen genellikle düşünceleri ve meseleyi algılayışları çok değişmemiş, farklı bir argüman geliştirememişlerdir.
Oku dergisi yazarları, kadının çalışmasına nas ve geleneksel kültürü gerekçe göstererek karşı çıkmışlardır. Onlara göre kadının çalışması ancak zorunluluk hallerinde mümkündür. Bu halde bile kadın, kocasından veya velisinden izin almalıdır, tesettürüne özen göstermeli ve mahremiyete dikkat etmelidir. Bu dönemin anlayışından olsa gerek 1980’lerde üniversitelerde boy gösteren tesettürlü kızlar için okumanın amacı çalışmak değildir. Tebliğde bulunmak, iyi bir eş ve anne olmak önceliklidir. Ancak kısa bir süre sonra muhafazakâr kadın öğretmen, hekim ve avukat olarak kamusal tecrübeye ortak olmuştur.
Ehl-i Sünnet Kelamında Tekvin Sıfatı İle İlgili Tartışmalar ve Eş arilerin Açmazları
Authors: Şahin Necati
Published: January 2023

Tekvin meselesi aslında hep insanın merakını celbeden bir konu olmuştur. Arap dilinde tekvin kelimesi tef’il babında k-v-n kökünden türetilmiş bir mastardır. Bu terim, tef’il kalıbında meydana getirme, yoktan yaratma gibi anlamlarda kullanılmaktadır. Tekvin meselesi aslında birçok açıdan tartışılmakla birlikte, yaratmanın yoktan olduğu konusunda genel olarak ilahi dinlerin ve özel olarak da İslam ekollerinin görüşleri birbirine yakındır. Eş’ariler yaratma konusunda eylemi gerçekleştiren bir sıfat olarak gördükleri kudret sıfatına ağırlık verirken, Maturidiler, kudret sıfatının yanında tekvin sıfatına ayrı bir önem atfetmişlerdir. Çünkü kudret sıfatı, bir şeye güç yetirilebileceğini ifade ederken, tekvin sıfatı onu kesin olarak ortaya koymayı ifade eder. Maturidilere göre tekvin, Allah’ın zatı ile kaim ezeli bir sıfat olmasından hareketle yaratma eylemi bu sıfatla gerçekleşmektedir. Burada Eş’ariler Matüridilerin aksine yaratma fiiilini kudret sıfatına yüklemekle hem güç hem de eylemin tek sıfatta gerçekleştiğini iddia etmektedirler. Halbuki bir şey hakkında güç ve kuvvet sahibi olmak, onunla ilgili bir tasarrufta bulunmak ayrı bir durumdur onu yaratmak varlık sahasına çıkarmak ayrı bir durumdur ve farklı sıfatlara sahip olmayı gerektirmektedir.
Kur an Perspektifinden Din-Bilim İlişkisi Abdulkadir KARAKUŞ
Authors: KARAKUŞ Abdulkadir
Published: January 2023

Din, Allah’ın sözlü âyetleri olan vahyini, bilim ise tabi olduğu yasaları bildirmek üzere Allah’ın evrene kodladığı sözsüz âyetlerini anlamayı konu edinen alanlardır. Din, yaratıcının kim olduğunu ve yaratılışın niçin gerçekleştiğini açıklarken bilim, yaratılışın nasıl gerçekleştiği üzerine yoğunlaşır. Bu iki alanın bilgi elde etme metotları birbirinden tamamen farklı olmakla beraber aynı hakikatleri değişik lisan ile ifade ederler. Bu sebeple birbirlerinin rakibi ve alternatifi değil aksine tamamlayıcısı konumundadırlar. Allah Kur’an’da çok açık ve anlaşılır bir şekilde insanları gözlem ve deney yoluyla yani bilimsel metotlar kullanarak varlıkla ilgili araştırmalar yapmaya, bunlar üzerinde düşünüp tefekkür etmeye teşvik etmiştir. Din, kendini bilimin doğrulamasına ihtiyaç duymayacak kadar açık, bilim de kullandığı metotlar itibarıyla somut ve anlaşılır bir alandır. Her ikisi de Allah’ın âyetlerini ele aldıkları için birbirlerini tamamlayan yönleri mevcuttur. Bu sebeple yaratılışla ilgili âyetlerin üzerinde durmadığı “Nasıl yaratıldı?” sorusunun cevabını merak edenlerin, bilimsel verilere yönelmesi gerekmektedir. Bu makalede, Kur’an âyetleri çerçevesinde bilim ve din ilişkisi ele alınmaya gayret edilecek ve her iki yolla elde edilen bilginin birbiriyle ilişkisinin sınırları tespit edilmeye çalışılacaktır
Recep KOYUNCU, Teoriden Pratiğe Vakf ve İbtidâ -Kur ân-ı Kerîm in Anlaşılması Bağlamında-
Authors: Aslan Emine
Published: January 2023

Kaynağı bizzat Kur’ân-ı Kerim’in kendisi olan vakf ve ibtidâ, kırâat ve tecvîd ilimlerinin en önemli alt dallarından biri olarak görülmektedir. Makâsıd-ı ilâhînin doğru bir şekilde anlaşılması ve içerdiği i‘câzın açığa çıkması; Kur’ân-ı Kerim kırâati esnasında nerede nasıl durulacağını ve nereden nasıl okumaya başlanacağını bilmeye imkân sağlayan bu ilimle mümkündür. Vakf ve ibtidâ kurallarına uyulmadığı, diğer bir ifadeyle gelişigüzel vakfedilip yine belli bir kaideye bağlı kalmaksızın ibtidâ edildiği takdirde ortaya çıkması muhtemel anlam değişimi ve bozulmalarına kapı aralanmış olur. Dolayısıyla bu ilmin Kur’ân’ın mânasıyla doğrudan ilişkili olduğu ve bir bakıma onun muhafazasını üstlendiği söylenebilir.
Tanıtımını yapacağımız bu eser, “Teoriden Pratiğe Vakf ve İbtidâ -Kur’ân-ı Kerim’in Anlaşılması Bağlamında-” başlığıyla kırâat ilmine dair kıymetli çalışmaları bulunan Recep Koyuncu tarafından doktora tezi olarak kaleme alınmıştır. Vakf ve ibtidâ ilmini Kur’ân-ı Kerim’in anlaşılması bağlamında kapsamlı bir şekilde ele alan çalışma, bir giriş ve üç ana bölüm olmak üzere toplam iki yüz yetmiş beş sayfadan müteşekkildir.
Pengembangan Soal Evaluasi Berbasis Game dengan Menggunakan Aplikasi Wordwall
Authors: Sholeh Muhammad , Hamzah Amir , Basuki Untung Joko , Susanto FX. Guntur Putra
Published: January 2023

Penggunaan teknologi informasi dalam mendukung proses pembelajaran sudah menjadi salah satu  kebutuhan yang harus dipersiapkan para guru. Guru harus menyesuaikan perkembangan    teknologi informasi. Guru harus beradaptasi dan menyesuaikan dengan anak-anak yang lebih banyak menggunakan teknologi informasi dan lebih pintar dalam menggunakan smartphone.  Banyak aplikasi yang dapat digunakan dalam mendukung proses pembelajaran berbasis teknologi infomasi. Salah satu aplikasi yang dapat digunakan dalam pembuatan soal online adalah dengan menggunakan aplikasi Wordwall. Tujuan dari kegiatan ini diantaranya memberikan alternatif kepada para guru dalam penggunaan aplikasi untuk membuat latihan soal online. Pemilihan aplikasi Wordwall dengan pertimbangan aplikasi tersebut mudah digunakan dan soal yang disajikan ke siswa dapat dipilih dalam bentuk permainan. Dengan mengemas dalam permainan diharapkan siswa merasa senang dalam mengerjakan soal. Metode dalam kegiatan dilakukan dengan memberikan pelatihan dan mempraktikkan secara langsung. Penggunaan metode praktik ini diharapkan para guru dapat langsung mengimplementasikan pembuatan soal. Hasil dari kegiatan ini,  para guru mampu mengembangkan soal online dan membentuk luaran soal dengan berbagai bentuk permainan dan mendistribusikan soal ke siswa
Developmental coordination disorder in school children- A systematic review
Authors: B. Sujatha , Somasundaram Sivaruban , Alagesan Jagatheesan , Adhitya P.S. Vikram
Published: January 2023

Developmental Coordination Disorder (DCD) is defined as a severe delay in perceptual-motor and psychomotor development that affects children who are intellectually normal and have no physical, sensory, or neurological conditions. It is described as a deficiency in the development of gross and fine motor abilities that cannot be accounted for by a lack of general education or exposure to equivalent opportunities to develop motor skills as their peers. Between May 2000 and May 2021, systematic reviews were published; these were included. The articles were shortlisted for full-text review after the reviewers independently read each title and abstract and determined that they looked at motor interventions intended to enhance movement skills in kids with developmental coordination disorder to improve fitness levels for the heart and lungs. This study looked at 72 review articles in total. The study included articles that offered advice on how to improve someone's cardiovascular and respiratory fitness. Activities such as organized sports, exercise, movement, balance training, and motor interventions were defined as motor interventions. According to the study's findings, kids with DCD have trouble moving about and are generally inactive. Conclusion: Improving motor skills and cardiorespiratory fitness have a significant impact on DCD children's quality of life.
A study on the utilization of Ayushman Bharat arogya scheme among patients admitted to a tertiary care hospital during Covid pandemic
Authors: Rao Amit Kumar , K Shrisharath , S Nanjesh Kumar , Hiremath Shivkumar , P Jagannath , S Erappa
Published: January 2023

Introduction and Aim: In India, most of the households face financial hardships due to catastrophic health care expenses. In response to covid-19 pandemic, the government launched the Ayushman Bharat Arogya Karnataka program, which offered health insurance for the coverage of covid-19 treatment costs and prevent families from undergoing financial hardships and incurring healthcare costs. The purpose of this study was to investigate and compare the utilization of the Ayushman Bharat insurance scheme among covid-19 positive and non-covid patients admitted to a tertiary care hospital in the Karnataka district of Dakshina Kannada.
 
Methodology: Data was collected from medical records of a tertiary care hospital in the Dakshina Kannada District of Karnataka for this cross-sectional study. The data collected was analyzed using the Microsoft Excel program, and the results subjected to statistical analysis using IBM SPSS software ver.20.
 
Results: The study found that there was a significant association between utilization of ABArK among patients (Covid and non-Covid) admitted to the hospital. While the utilization of ABArK among covid patients was found to be 51.3%, the utilization among non-covid patients was only 14.1% (X2= 1242.32, p value <0.001).
 
Conclusion: To improve the utilization of this scheme, public awareness activities must be conducted. As a result, less out-of-pocket expenditure would be incurred and access to healthcare facilities made easier.
Association of prolactin and insulin with obesity in women with polycystic ovarian syndrome
Authors: K. Lavanya , N. Palaniappan , V.M. Vinodhini , Kumar K. Mahesh , Silambanan Santhi
Published: January 2023

Introduction and Aim: Polycystic Ovarian Syndrome (PCOS) manifests with menstrual irregularities, infertility, galactorrhoea and hirsutism. Hormonal irregularities are found to be the pathogenesis behind PCOS. The study was aimed to evaluate whether obesity is associated with serum prolactin and insulin levels in PCOS women. 
 
Materials and Methods: This case control study was conducted in a tertiary care hospital in Chennai. Control group included 30 apparently healthy women and cases included 30 PCOS patients, diagnosis based on Rotterdam criteria. The individuals were of 20-40 years of age in both the groups. The serum prolactin and insulin were analysed by ELISA. The obtained data were checked for normality of distribution and subjected to statistical analysis. Receiver Operating Characteristics (ROC) curve was done. Statistical analyses were performed using SPSS version 16.0. P less than 0.05 was considered statistically significant.
 
Results: The median and interquartile range (IQR) of serum insulin were 11.5 (1.8-70) and 5 (1.8-44) mIU/L in cases and controls respectively. The cut-off level of insulin was 7.0 mIU/L. The median and IQR of serum prolactin were 12.5 (4.5-53.0) and 12 (3.5-20) ng/mL in cases and controls respectively. BMI was positively correlated with age of the participants and prolactin.
 
Conclusion: PCOS is prevalent among obese reproductive individuals. Insulin was markedly elevated in PCOS individuals. Insulin resistance alters levels of luteinizing hormone and sex hormone binging globulins. Hyperprolactinemia is associated with anovulation or oligoovulation, galactorrhoea and hirsutism. In obese PCOS women, prolactin and insulin could be diagnostic markers of PCOS.
In-vitro effectiveness of essential oils against isolated Klebsiella pneumoniae and Acinetobacter baumannii: A narrative review
Authors: T. M. Mohammed Anees , Deekshit Vijaya Kumar , Shetty A. Veena
Published: January 2023

Modern healthcare involves various invasive devices and procedures for better outcomes and recovery. It can be associated with healthcare-associated infections, including central line-associated, catheter-associated UTIs, and ventilator-associated pneumonia. Infections in ICU settings are serious and can lead to severe complications and higher morbidity rates. The infective pathogens in ICUs are drug-resistant, putting alarming pace with higher significance of alternative management and are one among the most significant encounters met by physicians and academicians. The inefficaciousness of existing pharmacological therapy has led to the identification and development of bioactive essential oils with higher antimicrobial potential. Essential oils are used in the formulation of drugs, cosmetics, and in food for their medicinal properties. Literature has revealed the susceptibility of microbes to the antimicrobial effects of essential oils and encouraged researchers to focus more on developing essential oils in nano-formulations to improve their antimicrobial effect. Encapsulation intensifications the antimicrobial efficacy of essential oils with controlled/sustained release and facilitates adjacent interaction. However, the exact mechanism involved is unknown. This review discusses the effectiveness and safety of essential oils expressed with MIC, MBC, and MIC/MBC ratios reported in various fragments of the world.
Role of serum lipoprotein(a) and its gene polymorphisms in cardiovascular burden among Indians: Coincidental association or causal relationship?
Authors: Kulkarni Vineet , Shetty Sukanya , Bhandary Roopa , Chakraborty Anirban , K. Subramanya
Published: January 2023

The increase in mortality rate due to coronary artery disease (CAD) is a major public concern among Indians. Smoking, obesity, type II diabetes are strong predisposing factors for CAD. However, the incidences of CAD in patients without these classical risk factors point to the need for identifying novel predictive biomarkers of CAD. The epidemiological studies conducted among European, African, Chinese populations, have demonstrated quite convincingly that Lipoprotein(a) is positively correlated with CAD. However, such studies are very few in the Indian context. It has been suggested that serum Lp(a) at levels more than 20mg/dL is independently associated with the risk of CAD among Indians, particularly in the young and immigrant population. Further, CAD subjects with comorbidities tend to have higher serum Lp(a) level compared to CAD subjects without any comorbidities. Genome wide association studies demonstrated that certain SNPs in the Lp (a) encoding gene (LPA), including rs10455872, rs3798220 and rs2266788 are more prevalent among Indians and are found to be strongly associated with CAD complications.  Thus, based on the results of limited studies conducted in the Indian population so far, serum Lp(a) appears to be a strong and reliable risk factor for the development of CAD among Indians. However, the role of other factors like serum triglycerides, total cholesterol, homocysteine and CRP also need to be considered in determining CAD risk. The focus in this review is to highlight the recent studies on the role of Lp(a) in cardiovascular diseases in Indian population, particularly in the context of genetic polymorphisms.
Gastroprotective effects of Triticum aestivum Linn., extract on ethanol-induced gastric ulcer in Wistar rats
Authors: Susan Oomen Sainu , Fernandes Hilda , Holla Rajendra
Published: January 2023

Introduction and Aim: Triticum aestivum (wheatgrass) is high in nutrient availability and antioxidant enzymes. It also functions as a detoxifier and aids in the rejuvenation of healthy cells. The current study sought to determine the gastroprotective impact of aqueous ethanolic extract of wheatgrass on the ethanol-induced gastric ulcer.

 

Materials and Methods: Wistar rats were given an oral dosage of 100% ethanol (1 ml/200g) to cause gastric ulcers. A reference medicine called omeprazole was given orally at dosages of 20 mg/kg body weight and 200 and 400 mg/kg of wheatgrass extract, respectively. Blood samples were taken an hour after ethanol administration, and the stomachs of deceased rats were then examined biochemically, macroscopically, and microscopically.

 

Results: The gastric ulcer index considerably decreased after taking wheatgrass extract orally, which showed a considerable attenuation of gastric ulcer. The serum level of TNF-? and the activity of the gastric MPO were both significantly enhanced by pre-treatment with wheatgrass extract. Furthermore, compared to the ethanol-induced group, wheatgrass pre-treatment dramatically boosted gastric levels of enzymatic and non-enzymatic antioxidants, including CAT, TAC, and GSH with concurrent reductions in MDA levels. Further evidence for these conclusions came from histopathology research, which showed that wheatgrass had a healing impact on the hemorrhagic shock brought on by ethanol poisoning.

 

Conclusion: Due to its propensity to decrease oxidative stress and gastric inflammation, wheatgrass extract may have gastroprotective effects on ethanol-induced stomach ulcers.
Extraction and characterization of nickel oxide nanoparticles from Hibiscus plant using green technology and study of its antibacterial activity
Authors: Al-saidi Muthana , Jaleel Ahmad Al-bana Read , Hassan Ekhlas , Laftaah AL-Rubaii Bahaa Abdullah
Published: January 2023

Introduction and Aim: Nanomaterials are tiny particles varying in size from 1-100 nanometers with wide implications in the fields of medicine, biology, and pharmaceutical sciences. In this study, we aimed to extract Nickel oxide nanoparticles (NiO-NP) from the tropical hibiscus plant, and evaluate these nanoparticles for their structural features as well as study the antimicrobial activity of NiO-NPs against Gram-positive and Gram-negative bacteria.
 
Materials and Methods: NiO nanoparticles were synthesized by green nanotechnology using hibiscus extract and nickel nitrate as precursors. The NiO nanoparticles obtained were investigated for its surface properties using X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy and UV-Vis analysis. Transmission Electron Microscopy (TEM) was used in calculating the size of NiO nanoparticles. The antimicrobial activity of the NiO particles was tested against E. coli and S. aureus test strains.
 
Results:  X-ray diffraction (XRD) and Fourier transform infrared (FT-IR) spectroscopy studies confirmed the formation of pure and well- crystallized NiO nanoparticles. The TEM analysis displayed that the size of nanoparticles to be within the limits of 71. The NiO-NP particles displayed antimicrobial properties and inhibited the growth of bacterial test strains used in this study.
 
Conclusion: The study demonstrated that nano Nickel oxide (NiO) particles could be successfully prepared using the hibiscus aqueous plant extract. The NiO-NP exhibited antimicrobial property against pathogenic E. coli and S. aureus bacteria, indicating that it could be used in formulations for treating infections by these organisms.
Green chili (Capsicum frutescens) ethanol extracts lowered triglyceride levels in rats fed with high-fat diet
Authors: Prawitha Pinatih Putu Teja , Ayu Dewi Ni Nyoman , Gede Sutadarma I Wayan
Published: January 2023

Introduction and Aim: Cardiovascular diseases (CVDs) are the world’s leading cause of death. Capsaicinoids, naturally occurring alkaloids found in Capsicum peppers, have been shown to lower plasma lipids and prevent atherosclerotic plaque formation. The present study aimed to compare the efficacy between Capsicum frutescens ethanol extract and statins on improving lipid profile in rats fed with high-fat diet.
 
Materials and Methods: Twenty-five 3 months’ old rats weighing approximately 200 ±10 g were divided into five groups of five rats each: normal-fed (NF), high-fat diet fed (FF), high-fat fed with 10mg/kg BW Capsicum frutescens ethanol extract (FF-C), high-fat fed with 0.36 mg statin (FF-S), and high-fat fed with Capsicum extract and statin (FF-CS). The experimental period lasted 6 weeks. Blood sample was then collected and analyzed for serum total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C).
 
Results: Between treatment groups, there was a significant difference of TC and TG levels (p < 0.05). The high-fat diet increased TC (mean difference (MD) 35.0 ± 9.7 mg/dL, p = 0.022) and TG (MD 76.67 ± 21.8 mg/dL, p = 0.026) significantly between NF and FF group. The addition of Capsicum frutescens decreased triglyceride levels significantly between FF and FF-C group (MD -39.4 ± 18.8 mg/dL, p = 0.038). No other significant difference was found between other treatment groups.
 
Conclusion: The addition of Capsicum frutescens ethanol extract has shown to be effective in lowering triglyceride levels, but not other lipid profile parameters, among rats fed with high-fat diet.
Effect of Cymbopogon citratus on biofilm production by multidrug resistant Acinetobacter baumannii
Authors: Aquinas Natasha , Suman Ethel , B. Dhanashree , Hegde Ashwini
Published: January 2023

Introduction and Aim: Acinetobacter baumannii, is the cause of many nosocomial infections which poses a serious threat to patients. Being a highly resistant organism, it has been placed in the critical priority list by WHO in 2017, thereby requiring newer effective drugs and alternative strategies. Increased antibiotic resistance has made it difficult to treat patients infected with this organism. The study aimed to find the biofilm forming ability of multidrug resistant A.baumannii causing respiratory tract infections, to find the genes responsible for biofilm production and to find the effect of Cymbopogon citratus (lemon grass) extract on biofilm.
 
Materials and Methods: The antibiogram profile was studied for the Acinetobacter isolates obtained from endotracheal aspirates, endotracheal tubing tips by antibiotic susceptibility testing and Vitek-2. Genes known to be associated with biofilm production, (AbOmpA, Bap) in Acinetobacter were detected by Polymerase chain reaction (PCR). The Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), Minimum Biofilm Inhibitory Concentration (MBIC), Minimum Biofilm Eradication Concentration (MBEC) of Cymbopogon citratus essential oil was determined by microtiter plate method.
 
Results: Isolates that were tested were found to be Multidrug resistant (MDR) and Extremely drug resistant (XDR) with highest resistance to Carbapenems (95.83%). Activity of Cymbopogon citratus EO was determined. The isolates predominantly showed MIC of 2% and MBC was 8%. MBIC was found to be 1%. However, Cymbopogon citratus EO did not eradicate the preformed biofilms. All 24 isolates showed AbOmpA gene and six showed presence of Bap gene.
 
Conclusion: This study demonstrated that isolates that produced the Bap gene were Extremely drug resistant (XDR). Biofilm formation was inhibited by Lemongrass essential oil (EO) but it did not eradicate the preformed biofilms.
Etiology, clinical and laboratory characteristics, and outcomes in patients with acute viral hepatitis
Authors: Ainura Kutmanova , Lira Imanbaeva , Aisuluu Buranchieva , Ainura Dzhangazieva , Mira Tursunbaeva , Gulkaiyr Zakirova , Tagaev Tugolbai , Vipin
Published: January 2023

Introduction and Aim: Kyrgyzstan is one of the most focused countries in the WHO European Region for acute viral hepatitis. The objective of this study is to evaluate the etiology, clinical and laboratory characteristics, and outcomes in patients with acute viral hepatitis.
 
Materials and Methods: This is a prospective study conducted on 122 patients with acute viral hepatitis at our hospital from March 2017 to June 2020. The diagnosis of acute viral hepatitis was based on the standard case definition: sudden onset with symptoms of a) acute illness (fever, malaise, weakness); b) liver damage (anorexia, nausea, jaundice, dark urine, right upper quadrant tenderness); c) elevation activity of alanine aminotransferase is more than ten times compared to normal levels.
 
Results: One hundred and twenty-two patients with acute viral hepatitis, including hepatitis A virus - 44 (36.1%), hepatitis B virus - 45 (36.9%), hepatitis C virus - 11 (9.0%), unspecified etiology - 22 (18, 0%). Patients with unidentified hepatitis, diagnosed through anti-HSV IgG was detected in 19 (86.4%) cases, anti-EBV IgG was detected in 18 (81.8%) cases, and 14 (63.6%) patients with anti-CMV IgG were present.
 
Conclusion: This study demonstrates the need to consider herpes viruses in the differential diagnosis of patients with unspecified liver lesions.
Role of videolaparoscopy in the surgical treatment of hepatic cystic echinococcosis
Authors: Toktogaziev Bakyt , Aitbaev Siezbek , Abdiev Allan , Toktosunov Arsen , Rysova Aiperi , Imankulov Mikhail , Yethindra Vityala , Kanteti Krishna Priya
Published: January 2023

Introduction and Aim: Cystic echinococcosis (CE) is the most common parasitic disease in Kyrgyzstan, which can affect all organs and organ systems of the body, but its most common localization is the liver and lungs. This study aimed to describe the possibilities and main stages of videolaparoscopy in the surgical treatment of hepatic CE.
 
Materials and Methods: Twenty-five patients aged 17-64 years who were under observation were admitted to the surgical department of our hospital from 2018-2022, were diagnosed with hepatic CE, and underwent surgical treatment by videolaparoscopy.
 
Results: The variant of the surgical technique was based on the use of three trocars including paraumbilical (basic – 10mm), epigastric (introduction and removal of a rubber sac with a chitinous sheath – 10 mm), and hypochondrium (on the right – 5mm). Only in three cases, it became necessary to include the 4th trocar mesogastric (on the right – 5mm), as demonstrated. The operation duration was 60±5 minutes. Drainage in the abdominal cavity was installed according to the location of the cavity and removed for 2-3 days.
 
Conclusion: Laparoscopic methods of treatment of hepatic CE provide greater efficiency when performed with proper surgical manipulations by considering the size and localization of cysts.
Cuidados paliativos en adultos mayores con cáncer de próstata
Authors: Espinosa Benítez Quenia Lorena , Jiménez Ayala Verónica Graciela , Bautista Rueda Irlanda Alicia
Published: January 2023

Introducción: El cáncer de próstata es de las enfermedades oncológicas que presentan mayor incidencia, con una probabilidad casi nula de encontrar una cura, por ello es necesaria la implementación de cuidados paliativos y de apoyo para mejorar la calidad de vida del paciente y su entorno durante su transición a través del cáncer. Objetivo: Analizar los cuidados paliativos en adultos mayores con cáncer de próstata Materiales y métodos: Revisión documental de investigaciones recientes y estudios clínicos tanto a nivel descriptivo, teórico como experimental enfocado en cuidados paliativos en adultos mayores con cáncer de próstata. Resultados: Un enfoque de cuidados paliativos, centrado en la calidad de vida y el alivio de los síntomas, puede servir como marco importante para brindar apoyo a los pacientes en sus últimos años de vida. Conclusiones: Los cuidados paliativos siguen siendo una disciplina relativamente nueva, requiere una mejor aplicación a nivel clínico, organizacional con soporte científico para lograr una integración eficiente al sistema de salud.
Estimating turbulent energy flux vertical profiles from uncrewed aircraft system measurements: Exemplary results for the MOSAiC campaign
Authors: Egerer Ulrike , Cassano John J. , Shupe Matthew D. , de Boer Gijs , Lawrence Dale , Doddi Abhiram , Siebert Holger , Jozef Gina , Calmer Radiance , Hamilton Jonathan
Published: January 2023

Abstract. This study analyzes turbulent energy fluxes in the Arctic atmospheric boundary layer (ABL) using measurements with a small Uncrewed Aircraft System (sUAS). Turbulent fluxes constitute a major part of the atmospheric energy budget and influence the surface heat balance by distributing energy vertically in the atmosphere. However, only few in-situ measurements exist of the vertical profile of turbulent fluxes in the Arctic ABL. The study presents a method to derive turbulent heat fluxes from DataHawk2 sUAS turbulence measurements, based on the flux gradient method with a parameterization of the turbulent exchange coefficient. This parameterization is derived from high-resolution horizontal wind speed measurements in combination with formulations for the turbulent Prandtl number and anisotropy depending on stability. Measurements were taken during the MOSAiC expedition in the Arctic sea ice during the melt season of 2020. For three example cases from this campaign, vertical profiles of turbulence parameters and turbulent heat fluxes are presented and compared to balloon-borne, radar and near-surface measurements. The combination of all measurements draws a consistent picture of ABL conditions and demonstrates the unique potential of the presented method for studying turbulent exchange processes in the vertical ABL profile with sUAS measurements.
The Four-Wavelength Photoacoustic Aerosol Absorption Spectrometer PAAS-4λ
Authors: Schnaiter Franz Martin , Linke Claudia , Asmi Eija , Servomaa Henri , Hyvärinen Antti-Pekka , Ohata Sho , Kondo Yutaka , Järvinen Emma
Published: January 2023

Abstract. In this paper the Photoacoustic Aerosol Absorption Spectrometer PAAS-4λ is introduced. PAAS-4λ was specifically developed for long-term monitoring tasks in (unattended) air quality stations. It uses four wavelengths coupled to a single acoustic resonator in a compact and robust set-up. The instrument has been thoroughly characterized and carefully calibrated in the laboratory using NO2/air mixtures and Nigrosin aerosol. It has an ultimate 1σ detection limit below 0.1Mm-1 at a measurement precision and accuracy of 3 % and 10 %, respectively. In order to demonstrate the PAAS-4λ suitability for long-term monitoring tasks, the instrument is currently validated at the air quality monitoring station Pallas in Finland, about 140 km north of the Arctic circle. Eleven months of PAAS-4λ data from this deployment are presented and discussed in terms of instrument performance. Intercomparisons with the filter-based photometers COSMOS, MAAP, and AE33 demonstrate the capabilities and value of PAAS-4λ, also for the validation of the widely used filter-based instruments.