bluuebunny/crossref_metadata_2025 huggingface dataset:
Study Of The Marketing Development Of Tilapia (Oreochromis Niloticus) In Soppeng Regency
Authors: A. Nadia Mughsita Sani  , Hamzah  , Sri Suro Adhawati
Published: January 2024

This research examines the policy strategy for developing tilapia marketing in Soppeng district. Marketing development is needed to achieve equal distribution of profits from the tilapia business for marketing institutions. The PPA was carried out through a meeting of coastal area management planning experts, as part of the development of tilapia marketing. PPA aims to involve stakeholders to produce identification and definition of key variables, definition of future state variables, scenario building, and formulation of strategies and anticipated actions. The FGD results obtained 6 variables with the highest scores, namely consumer understanding, digital marketing, market demand, government support, distribution and supply chain, sustainable marketing. In this context, the participants created implementation strategies and anticipatory actions, (1) Providing education to people who will become consumers about the importance of consuming fish that is rich in nutrients; (2) digitizing tilapia fish business actors; (3) Pay attention to and record the stock and demand for Tilapia fish; (4) paying more attention to business actors (fishermen and fish farmers) as a measure for regional food security; (5) Providing opportunities and supporting the Tilapia distribution and supply chain (6) Creating a fisheries system from raw materials, then processing them carefully so that no waste is left, then creating a culinary village program containing fishing spots for consumers and restaurants with a fisheries menu . The strategic implications and anticipatory actions above are stakeholder needs that can be met through intervention in various determining variables in Tilapia Marketing Development.
Overview of Site Effects and the Application of the 2022 New Zealand NSHM in the Wellington Basin, New Zealand
Authors: Kaiser Anna Elizabeth , Hill Matt P. , de la Torre Chris , Bora Sanjay , Manea Elena , Wotherspoon Liam , Atkinson Gail M. , Lee Robin , Bradley Brendon , Hulsey Anne , Stolte Andrew , Gerstenberger Matt
Published: January 2024

We provide an overview of the treatment of site effects in the New Zealand National Seismic Hazard Model (NZ NSHM), including a case study of basin effects in central Wellington. The NZ NSHM 2022 includes a change in site parameter from subsoil class (NZS class) to VS30. Poor NZ VS30 characterization is a major source of uncertainty in the NSHM; however, advanced site characterization in Wellington allows for in-depth study. First, we construct a regional 3D shear-wave velocity model and maps of site parameters (T0, NZS class, and VS30) for central Wellington. At central city soil sites, we find the ratios of NZ NSHM 2022 hazard spectra with respect to the current equivalent design spectra range from factors of ∼0.8–2.6 (median ∼1.5), depending on local site conditions and spectral period. Strong amplification peaks at 0.5–2 s are observed in central Wellington. Linear site-specific amplifications from multiple methods are compared at 13 stations and are well-defined by both site-to-site residuals and response spectral ratios relative to station POTS. At many deeper soft sites (VS30<300  m/s), strong amplification peaks occur around T0 that are underpredicted by mean ergodic ground-motion model (GMM) predictions. This underprediction is slightly enhanced when using basin-specific Z1.0 as an additional site parameter. Our study highlights outstanding challenges in modeling strong basin response within shallow basins in NSHMs, including the need to consider region- or basin-specific modeling approaches as well as nonlinear effects at high shaking intensities that dominate the hazard. For New Zealand, in general, as illustrated in the Wellington case study, a priority is the further characterization of VS30 (and VS) for the seismic network to better isolate and quantify uncertainties in seismic hazard and allow useful exploration of regional–GMM adjustments and partially nonergodic approaches.
Event study announcement of fraud and abnormal returns of BUMN companies
Authors: Nafisa Umi Zahrotin , Makaryanawati Makaryanawati , Yusoff Haslinda
Published: January 2024

Abstract This study aims to determine the effect of fraudulent financial reporting of BUMN on abnormal returns. This study is important because most of the research examining these events has been conducted in developed markets. This study uses an event study approach with a window period of five days before and five days after the incident. By using the purposive sampling method, five BUMN companies that were reported to have committed the fraudulent in 2019 was selected in this study. The result shows that the incident of fraudulent financial report announcements does not significantly affect abnormal returns. This finding shows that the investors reaction the fraudulent news be not significant. This concludes that the news of fraudulent BUMN companies is not strong enough to influence investment decisions in the capital market. The results of this study are useful for investors in considering investment decisions in state-owned companies because they have fundamentally strong capital, so investors feel safe to invest. The results of this study contribute to the literature by adding new insights about fraud announcement events in BUMN. The results of this study also support the signal theory concept because investors respond to the second and third events as bad signalsAbstrak Penelitian ini bertujuan untuk mengetahui pengaruh peristiwa pengumuman kecurangan BUMN terhadap abnormal return. Penelitian inipenting untuk dilakukan karena sebagian besar penelitian yang mengkaji peristiwa tersebut dilakukan di pasar negara maju. Penelitian ini menggunakan pendekatan event study dengan periode jendela lima hari sebelum dan lima hari setelah peristiwa. Dengan menggunakan metode purposive sampling, lima perusahaan BUMN yang diberitakan melakukan kecurangan pada tahun 2019 menjadi sampel dalam penelitian ini. Hasilnya menunjukkan bahwa peristiwa pengumuman kecurangan tidak berpengaruh secara signifikan terhadap abnormal return. Temuan ini menunjukkan bahwa reaksi investor atas berita kecurangan tidak signifikan. Artinya berita kecurangan perusahaan BUMN tidak cukup kuat untuk memengaruhi keputusan investasi di pasar modal. Hasil penelitian ini bermanfaat bagi investor dalam mempertimbangkan keputusan investasi di perusahaan BUMN karena memiliki modal yang kuat secara fundamental, sehingga investor merasa aman untuk beinvestasi. Hasil penelitian ini berkontibusi pada literatur dengan menambah wawasan baru tentang peristiwa pengumuman kecurangan di BUMN. Hasil penelitian ini juga mendukung konsep teori sinyal karena investor merespons peristiwa kedua dan ketiga sebagai sinyal buruk
Analysis of Risks Arising from the Use of Autonomous Vessels
Authors: Šikić Mario , Jančić Andro , Jureško Mihovil , Mohović Đani
Published: January 2024

This paper focuses on the analysis of risks arising from the use of autonomous ships. The concept
of autonomy is defined, different levels of autonomy are mentioned, and the differences between
unmanned vessels and autonomous ships are well known. The transition to autonomous ships
brings certain risks that need to be managed. Therefore, this paper analyses the risks associated with
autonomous ships, which have received significant attention in recent years. An important aspect in
considering risks is human error, which according to various studies is the most common cause of
maritime accidents. However, autonomy also has the potential to create accidents, which manifest
in five unacceptable hazards in the initial configuration of the ship. The main hazard human error,
interaction with manned vessels and object detection, interaction with the physical environment, system
failure, cyber-attacks, and equipment failure. The focus of the ship’s work is to prevent and reduce the
probability of critical events and their causes and maximize operational efficiency and performance.
A retrospective and observational study of the adverse drug reactions reported in a tertiary care hospital
Authors: Vemuri Veena Rani
Published: January 2024

Background: Adverse drug reaction (ADR) is considered a common cause of prolonged hospitalization and death among patients. Pharmacovigilance is essential in the surveillance of adverse drug reactions. The responsibility of a healthcare professional is to report any adverse reaction that occurs with the use of drugs. This helps in providing a database and improving the safety of patients. The aim of the study was to determine the incidence of ADR, assess causality, severity, and preventability of the submitted adverse drug reactions, increase the awareness of preventability of adverse drug reactions in health care professionals by conducting regular workshops on ADR, and document occurrence of a rare ADR.
Methods: A retrospective observational study was conducted to assess the ADR reported to the ADR monitoring Centre, for the past 6 years included in the study. The data were entered into Microsoft excel and analyzed using descriptive statistics. Mean and standard deviation were calculated for the categorical data. Drugs were classified according to the class. Reactions were analyzed using scales and presented in descriptive statistics.
Results: A total of 95 ADR reports were received and reported. These ADRs were associated with a total of 108 drugs that were prescribed- the occurrence of ADRs dominated among females 60% (57). Antimicrobials were causing the highest number of adverse reactions 21 (19.44%) and antituberculosis drugs and radiocontrast media were associated with the following larger number of the ADRs 19 (17.59%).  Intravenous at 40% was the most common route related to the development of ADR. The most common ADR caused by antimicrobials was rash (9), antitubercular therapy commonly caused hepatitis, and chills and rigors were more common with radiocontrast media. Most of the reactions observed in the patients were moderate reactions at 52.63% with 3.16% fatal ones.
Conclusions: In this study, the predominant causative drugs associated with ADR were antimicrobials, antitubercular drugs, and radiocontrast media. The number of ADRs reported though was less there was a wide range of drugs causing ADR that were reported which gave a broader spectrum for analysis. There is a requirement for active monitoring of ADRs to understand the occurrence as well as help in prevention.
A Quasi-experimental study on the effectiveness of primary caregiver social support capacity on self-management practices of clients living with type II diabetes in Machakos county, Kenya
Authors: Kiarie Jackline Njeri , Mambo Susan Njoki , Kamundi George Kimathi
Published: January 2024

Background: Diabetes is a fast-growing public health emergency, projected to affect 643 million people by 2045. While primary caregiver social support can influence the self-management practices of Type 2 diabetes (T2D) clients, there's often limited capacity to provide it. The study determined the effectiveness of enhanced caregivers' social support capacity on self-management practices of T2D clients in Machakos.
Methods: A six-month quasi-experimental study design that adopted quantitative and qualitative data collection and analysis approaches. Primary caregivers at the Matungulu intervention site were trained on T2D self-management and types of social support, with no intervention conducted at the Masinga control site.
Results: Over 90% of the 227 primary caregivers were female, with a mean age of 43.28, supporting approximately three T2D clients each. Post-intervention, a 27.2% change in capacity to identify all T2D self-management practices was noted compared to a 7.6% change in the control group. The greatest contribution was in the primary caregivers' ability to provide tangible, followed by emotional and informational social support, resulting in a statistically significant improvement in the self-management practices in the intervention site, B=0.140 (95% CI: 0.072, 0.208), t=4.046, p<0.001. Consequently, the difference in blood glucose levels was statistically significant, crude OR=3.213 [95% CI: 2.039, 5.063], p<0.001.  
Conclusions: Enhanced capacity to provide social support positively correlates with the T2D clients' self-management practices. Further investigation of factors that hinder the full realization of primary caregiver social support capacity benefits in improving self-management capacities among T2D clients is recommended.
Imagen Hauntológica
Authors: GAVILANES PANDO GEOVANNY
Published: January 2024

El presente artículo aborda a la fotografía analógica en la contemporaneidad como resultado de una búsqueda de la imagen hauntológica, definición emergente a partir de los conceptos de hauntología y hauntología sónica planteados por Jacques Derrida y Mark Fisher respectivamente. En la primera parte, se aborda el proceso de cambio tecnológico y cultural desde las primeras cámaras de madera y cartón hasta la modernidad digital del sensor y el pixel. En la segunda parte, se exploran aplicaciones móviles, el cambio del entorno fotográfico gracias a las redes sociales y filtros de software. Finalmente, como respuesta a la pregunta ¿porqué usamos cámaras de rollo y artefactos del pasado en la modernidad del iPhone? se propone el concepto de imagen hauntológica, que se encuentra en la búsqueda de un pasado virtual en una equivalente nostalgia material por medio de procesos y circuitos fotográficos combinados entre analógico y digital.

PALABRAS CLAVE: Fotografía, Renacimiento analógico, hauntología, culture visual, nostalgia.
que compensa mais: gasolina ou etanol?
Authors: Ester Gonçalves Thais , Deodato André Augusto
Published: January 2024

Neste artigo apresentamos o relato de uma experiência vivenciada durante a disciplina de Estágio Supervisionado, em especial, durante a regência de uma aula na qual foi realizada uma atividade investigativa. Assim, estabelecemos como objetivo analisar as estratégias adotadas pelos alunos durante tal atividade, na qual noções de porcentagem foram mobilizadas para reflexão sobre o consumo de combustível em automóveis. Para tanto, do ponto de vista teórico, o relato lança mão de um conceito de investigação que ressalta a importância de se valorizar o papel social da Matemática na sociedade. Do ponto de vista metodológico, nos valemos da legitimidade reconhecida nas pesquisas sobre a própria prática. Torna-se imperativo ressaltar que o material, sobre o qual incidirá a análise, foi produzido a partir do acesso aos registros de uma aula no relatório de estágio e no diário de campo de um dos autores. Como principais resultados, destacamos: i) a atividade  investigativa pareceu ter incentivado  os alunos no sentido de utilizarem o conceito de porcentagem para comparar qual combustível era economicamente mais vantajoso, a partir de uma ação de coletar informações reais sobre os preços praticados pelos postos de combustível da cidade em que residiam; ii) por meio da atividade investigativa, os estudantes fizeram uso de duas estratégias diferentes para o cálculo de porcentagens.
Multi-level territorial monitoring in Switzerland as a case in federalism and multi-polarity
Authors: Kellenberger Marco
Published: January 2024

In Switzerland, spatial observation and monitoring systems are very much defined and implemented at the various levels of government. This takes into account the fact that the main challenges and issues differ greatly not only between the levels of government but also regionally. The exchange processes between the levels of state, as well as between the various actors at the respective levels are interwoven in many ways, and this peculiarity of political work is also reflected in the implementation of indicator and monitoring systems. Although strongly characterised by the subsidiarity and independence of the respective level, a lively and well-balanced interaction between different actors can also be observed. This results in a somewhat multipolar picture within and across the levels, with a strong focus on cross-sectoral coordination and cooperation. The main goal of this article is to give an insight into and to deepen the understanding of the main characteristics and processes, dependencies, and interactions in the context of territorial monitoring in Switzerland. The insight is provided from a rather subjective perspective and based on a long-time institutional experience in this field.
Z rodziną wychodzi się najlepiej na zdjęciu. Relacje Raskolnikowów w powieści Zbrodnia i kara Fiodora Dostojewskiego
Authors: Kożuchowska Julia
Published: January 2024

Tematem artykułu jest próba analizy rodziny Raskolnikowów oraz relacji pomiędzy poszczególnymi jej członkami w powieści Zbrodnia i kara Fiodora Dostojewskiego.

W badaniach wykorzystano metody psychoanalizy Jacques’a Lacana i Carla Gustava Junga oraz hermeneutykę.

Człowiek jako stworzenie stadne od zarania dziejów tworzy swego rodzaju rodziny. Rodzina jest podstawową i bardzo ważną grupą społeczną, do której przynależą ludzie. Rodzice uczą dzieci zachowań i reakcji na dane sytuacje, przekazują im zasady moralne i poświęcają się dla prawidłowego rozwoju potomstwa. Rodzice są wzorami do naśladowania dla dzieci i na podstawie obserwacji zachowań dorosłych dzieci kształtują swój charakter, mechanizmy obronne oraz światopogląd. Ważnym nauczycielem umiejętności interpersonalnych jest również rodzeństwo, które uczy między innymi kompromisów, zdolności negocjowania oraz odpowiedzialności za innych. Rodzina Raskolnikowów jest niepełna z powodu samobójczej śmierci ojca, którego nieobecność odbiła się na życiu Pulcherii, Rodiona i Awdotii. Mimo trudnej sytuacji życiowej, ubóstwa i różnorakich problemów, każdy z członków rodziny okazuje wobec innych szacunek, troskę i gotowość do poświęceń. Każde z nich przedkłada dobro innych nad swoje, nie oczekując niczego w zamian. Zbrodnia Rodiona wpłynęła na jego relacje z matką i siostrą, przez co ich stosunki uległy pogorszeniu, lecz ostatecznie losy każdego z bohaterów kończą się szczęśliwie.
A Delirium Prevention and Management Initiative: Implementing a Best Practice Recommendation for the NICU
Authors: Hardin Barbara G. , McCarter Andrea , Hamrick Shannon E. G.
Published: January 2024

Medically complex infants experiencing NICU stays can be difficult to manage, exhibiting refractory agitation, disengagement, or both—all signs of delirium, which can present in a hypoactive, hyperactive, or mixed form. Though documented in other settings, delirium is under-recognized in NICUs. Pediatric studies show that a high percentage of patients with delirium are under the age of 12 months. Delirium is associated with increased ventilation days, hospital days, and costs. It negatively affects neurodevelopment and social interaction. Studies show that pediatric nurses are unprepared to recognize delirium. Our nurse-led multidisciplinary group created a best practice recommendation (BPR) focused on detecting delirium and minimizing risk through thoughtful sedation management, promotion of sleep hygiene and mobility, and facilitation of meaningful caregiver presence. Occasionally, medications, including melatonin and risperidone, are helpful. In 2019, we introduced this BPR to reduce delirium risk in our NICU. Practice changes tied to this initiative correlate with a significant reduction in delirium scores and risk including exposure to deliriogenic medications. A multidisciplinary care bundle correlates with decreased delirium screening scores in NICU patients.
УРБАНОНИМИ НОВОГ САДА У РОМАНУ КЊИГА О БЛАМУ
Authors: Marković Željko
Published: January 2024

У раду су разматрани урбаноними Новог Сада који чине топономастикон романа Александра Тишме Књига о Бламу. Тај топономастикон упоређен је са стварним топономастиконом града из времена приказаног у роману и анализирана су одступања која у односу на њега показује.
Protective effect of Moringa oleifera leaves extract on cardiac fibrosis of streptozotocin-induced diabetic rats
Authors: Salsabila Zadia Maheswari , Suryono . , Pralampita Pulong Wijang
Published: January 2024

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia that induces excessive reactive oxygen species (ROS) production and  causes oxidative stress. Diabetic cardiomyopathy is a diabetic complication characterized by structural and functional changes of the myocardium. Fibrosis is one of the pathological features of diabetic cardiomyopathy. Moringa oleifera leaves have been reported to possess antidiabetic and antioxidant activities which could prevent diabetic complications such as cardiomyopathy. A previous study reported that M. oleifera leaves extract have protective effects to the kidneys and liver of rats exposed to oxidative stress. This study aimed to investigate the protective effect of the M. oleifera leaves extract on cardiac fibrosis of rats induced by streptozotocin (STZ).  This was an experimental study using a posttest-only control group design. Thirty-three male Wistar rats were randomly divided into three groups i.e. normal control  group (Group 1) were administered normal saline, diabetic control group (Group 2) were administered normal saline, and diabetic treatment group (Group 3) were administered M. oleifera leaves extract. Diabetes induction of rats was conducted by intraperitoneally injection of STZ at dose of 45 mg/kg BW. The M. oleifera leaves extract at a dose of 1000 mg/kg BW was administered orally one time a day for 28 days. Statistical analysis was performed using the Kruskal-Wallis test followed by Mann Whitney. A significant difference in cardiac fibrosis occurrence between three groups was observed (p < 0.05). No cardiac fibrosis was observed in normal control group, meanwhile cardiac fibrosis was observed in all rats (9 rats) of the diabetic control group (G2). Only 2 rats in the treatment group (G3) had cardiac fibrosis. In conclusion, M. oleifera leaves extract can inhibit cardiac fibrosis in STZ-induced diabetic rats.
On some peculiarities of the renewal of national higher education system in Russia
Authors:   International Academy of Sciences of Higher Education, Senashenko Vasily S.
Published: January 2024

The purpose of this work is to discuss the problems that arise at the next stage of the renewal of the national system of higher education. Based on the results of the study, the author assesses the planned structural changes in higher professional education in Russia, the degree of their continuity with the existing structure of higher education, identifies the emerging features of the main educational programs of higher education, the degree of their compliance with the new requirements for specialists with higher professional education in various sectors of the national economy. It is shown that the proposed restructuring of the main educational programs of higher education needs a thorough adjustment, since it does not solve the problem of high-quality training of specialists with higher professional education based on the conjugation of the main educational programs of higher education and the sphere of work.
Axiological ambiguity of the social selection in education
Authors:   Volgograd State Technical University, Soloviev Andrey A.
Published: January 2024

The relevance of the problem is caused by the need for young people to make a conscious choice of life priorities and guidelines. The purpose of this article is to study the value foundations of individual choice and social selection in education. Different approaches to understanding the significance of the selection function of educational activity are presented. A classification of the priorities of professional and social choice, as well as criteria for choosing the optimal method of individual development, has been completed. The factors that determine the meaning of education in historical retrospect are studied. The internal mechanisms of the professional and educational structure of society, making it a channel of social mobility, are considered. At the same time, a position is presented that shows the ambiguity of the influence of one or another mechanism on the future — some events can simultaneously contribute to both vertical and horizontal mobility. The author also strives to identify the axiological principles of establishing the boundaries of attributing a particular case to different social elevators. The question is raised about the moral choice of a teacher when organizing teaching activities that take into account the abilities and prospects of students. The ambivalence of this situation in relation to the influence on the further activity of the subject is pointed out, and in this sense, both the inconsistency and the dialectical unity of social selection and personal choice are established.
Teacher training in Ivory Coast
Authors:   Yaroslavl State Pedagogical University named after K.D. Ushinsky, Danilova Larisa N.
Published: January 2024

In recent years, there has been a significant reinforcement of mutually beneficial cooperation between Russia and African countries on the broad agenda. Russia builds these relations, taking into account new African realities and on the principles of sovereignty respect, national interests and equality. Today, the African agenda actively reflects in political meetings, economic forums, and scientific conferences, where the most famous is the Russia-Africa Forum of 2019 and 2023. In Ivory Coast, a diplomatic mission first appeared 7 years after gaining sovereignty, but then the ties were severed on Ivorian initiative due to the remaining significant French influence. Since 1986, the relations have been friendly and today they cover political dialogue, security, trade and economics, investments, energy, mining and new technologies, scientific exchanges, cultural, educational areas, etc. The educational sphere has traditionally been represented only by the practice of studying Ivorians in Russian universities. Nowadays, Russia participates in educational projects already in Ivory Coast. But their educational system is very poorly covered in Russian scientifical literature. The objectives of the article are to identify specifics of teacher training in Ivory Coast and to determine its problems and achievements.
Opioid promotion in Canada: A narrative review
Authors: Lexchin Joel
Published: January 2024

Studies based on the United States Open Payment database have demonstrated an association between the promotion and prescribing of opioids. An equivalent database does not exist in Canada; therefore, I undertook a narrative review of the literature. In 2015, Purdue spent over CAN$4 million promoting a single product and generated over 160 pages of journal advertising. In the current review, I describe each of the six different forms of promotion that companies used to try and influence prescribing behaviour: messages from sales representatives, journal advertisements, company involvement in undergraduate medical education, key opinion leaders, clinical practice guidelines, and the funding of patient groups. Recent regulatory changes have decreased the volume of opioid promotion, but it would be incorrect to assume that it does not continue to influence the prescribing of this class of drugs.
Global Trade: Long-Term Trends and Structural Changes
Authors: Varnavskii V.
Published: January 2024

The paper considers long-term trends of global trade and there structural changes. We determine the elasticity of trade to GDP and the dynamics of the ratio of goods and services exports, as well as structural shifts in the major countries and regions of the world. The case study was focused on the USA–China trade relations and contradictions. Since 2007, PRC is the undisputed world’s largest exporter of goods. According to author’s estimates, in 2022 China was ahead of the United States in the total merchandise export by 1.5 trillion dollars. This corresponds to 6.3% of total world exports or 5.8% of US GDP. The trade war unleashed by former president D. Trump administration in 2018–2019 inevitably resulted in a decline in bilateral trade. However, this was just a temporary trend. The recent WTO statistics shows that US imports from China recovered by 2021 both in general volume and in the main categories of goods, both for intermediate and final consumption. Moreover, in 2022 its value, in particular for the analyzed commodity groups (aluminum, iron and steel) exceeded the indicators of 2017–2018. The author argues that, most importantly, there are long-term and fundamental implications of the trade conflict between the US and China rather than a transient decrease in mutual trade between the two flagships of globalization. In particular, it substantially exacerbated the protectionist biases in the international trade policies that became evident after the global financial crisis of 2008–2009. It triggered appearance of new rapidly rising actors at the international trade field such as India and Brazil. This points at major underlying shifts in the global production and supplies schemes. Basically, tensions between the two flagships of globalization produced much higher uncertainty in the global trade which, in the next decade, is unlikely to show the dynamics comparable to that of the period 2002–2008.
A New Readahead Framework for SSD-based Caching Storage in IoT Systems
Authors: Chang Hsung-Pin , Su Wei-Ming , Chang Da-Wei
Published: January 2024

In an IoT system, the sheer volume of data generated by numerous sensing devices necessitates a well-designed scheme for storing and retrieving data efficiently, enabling streamlined data processing and analytics. One promising storage architecture involves utilizing solid-state drives (SSDs) to cache data from hard disk drives (HDDs), thereby creating an SSD-based caching storage system. To further enhance access performance, it is possible to employ readahead techniques to minimize data access latency. However, the existing Linux readahead scheme falls short in fully leveraging SSD-based caching storage systems. We address this limitation by introducing a novel cross-layered readahead architecture that effectively communicates with the VFS layer, the file system layer, and the block I/O layer. This communication facilitates the acquisition of readahead timing, readahead data continuity, and readahead data location, respectively. To guide prefetching decisions, our architecture analyzes the degree of data access sequentiality, the performance model of the target storage device, and the access patterns of the I/O workload on the corresponding storage device. The implementation of this new architecture in the Linux kernel yields promising experimental results, demonstrating its robustness by consistently outperforming the stock Linux kernel. Notably, our architecture reduces the total execution time of the stock Linux kernel by up to 49%, except in cases of random workloads where both the stock Linux kernel and our architecture exhibit similar performance.
AOA Critical Issues Symposium: The Dynamic Environment of Health Care
Authors: Lundy Douglas W. , Jevsevar David S. , Porter Scott E. , Miller Thomas L.
Published: January 2024

The dynamic health-care environment continues to undergo disruptive change. As the health-care system emerges from the pandemic, underlying issues have progressively become critical. Private equity acquisition is dramatically increasing, and consolidation in the entire health-care system limits choice and access. Challenges in the workforce and supply chain persist, adding pressure on already strained health-care organizations. Innovative solutions are required to provide equitable value-based access to orthopaedic care.
Tumu College of Education trainee teachers’ perceptions of mentors’ pedagogical knowledge
Authors: Osman Shani , Dangor Kassim File
Published: January 2024

The study accessed the perceptions of final year students in the Tumu College of Education towards the Pedagogic Knowledge (PK) of their mentors. It also investigated whether statistically significant differences existed in terms of mentees’ gender and programmes of study regarding the pedagogic knowledge of their mentors. The study used a census method to collect data from respondents for the study by distributing a closed-ended five-point Likert scale on Perceptions of Knowledge and Skills in Teaching (PKST) Questionnaires to all 215 students pursuing Early Grade and Primary Programmes, with an 84.2% (181) return rate. However, 175 respondents’ data were used, as six of the questionnaires contained incomplete data. Findings of the study revealed that participants perceived their mentors as having a high measure of PK, with an overall mean value for the student teachers ‘perceptions of their mentors PK of 3.62 (SD =.77). The study also revealed that there was no statistically significant difference in the perceptions of student teachers towards the PK of their mentors in terms of gender or programme of study. However, the study revealed that participants perceived their mentors to be less competent in effectively incorporating information and communication technology (ICT) in the classroom. It is recommended that the Ministry of Education and Ghana Education Service organise capacity building workshops for teachers to improve their competencies in integrating ICT in their classrooms.
Phosphorus fractions distribution and their relationship with physiochemical properties in the Agricultural soils of Yamuna River Region.
Authors: Sheshu Mutyalu , Hasan Amreen , Thomas Tarence , David Arun Alferd , Baradwal Akshita , Khatna Raghu Nandan Singh
Published: January 2024

Purpose: To expand research on soil phosphorus. Little is known about the concentrations of phosphorus fractions in the phosphorus-deficient area of the Yamuna River bank in Prayagraj. To overcome this gap, we suggest the exploitation of soil phosphorus fractions from soil samples in the study area.
Methods: We analysed 24 soil samples from four different depths at six different sites in agricultural fields around the Yamuna River. Samples were analysed, and different phosphorus fractions were sequentially extracted, followed by UV Spectrometry analysis of individual P fractions.
Results: We found that P-deficient soils were neutral in pH and low in salinity. Among the P fractions, calcium-P was the most predominant, followed by Fe-P, S-P, Occl-P, Red-P, and Al-P. The Overall results showed that available P, organic P, and Total-P decreased with increasing depth, whereas calcium P was significantly positively correlated with organic carbon ( r = 0.55*) and available nitrogen ( r = 0.55*), and significantly negatively correlated with clay (r = -0.32*), pH ( r = -0.22*), and EC ( r = -0.23*). Howe ever Occulated-P is a major contributing factor to the availability of P in soils.
Conclusion: Our regression equations showed that soil pH was the main soil property influencing the different P fractions. Applying organic P fertilizers can improve the quantity of P in these soils, and if enhanced analytical techniques are applied to soil samples, it is possible to gain more detailed insights into the dynamics of phosphorus fractions.
Associations Between Obstructive Sleep Apnea and Allergic Diseases: A Two-Sample Mendelian Randomization Study
Authors: Chen Jiaqin , Ma Xiaolu , Zhao QI , Zhang Zhongmian , Lin Zili , Wang Bin
Published: January 2024

Objectives:The objective of this study was to assess the causal relationship between obstructive sleep apnea (OSA) and allergic conditions including allergic asthma, allergic rhinitis, allergic conjunctivitis, and atopic dermatitis.
Design:We conducted a Mendelian randomization analysis to assess a potential causal relationship between OSA and allergic disease.
Setting and participants:All candidate gene data were from the IEU GWAS database, where OSA candidate genes included 16,761 cases and 201,194 controls, and the allergic disease dataset included allergic asthma (4,859 and 135,449 controls), allergic rhinitis (7,308 and 167,849 controls), allergic conjunctivitis (9,431 and 203,517 controls), and atopic dermatitis (7,024 and 198,740 controls).
Results:MR analysis using the IVW approach demonstrated that OSA was associated with a slight increase in the risk of allergic asthma (odds ratio [OR]=1.16; 95% confidence interval [CI]: 1.02–1.33; p = 0.019). Furthermore, compelling evidence emerged, indicating that OSA is associated with an elevated risk of other allergic conditions, such as allergic rhinitis (OR=1.16; 95% CI: 1.04–1.29; p = 0.006), allergic conjunctivitis (OR = 1.15; 95% CI: 1.05–1.27; p = 0.002), and atopic dermatitis (OR=1.16; 95% CI: 1.03–1.30; p=0.002). These results collectively contribute to a better understanding of the potential causal relationships between OSA and various allergic diseases.
Conclusion: The findings of the two-sample MR analysis indicated that OSA exhibited a potential increased risk of allergic diseases.
Automatic Beam Optimization Method for Scanning Electron Microscopy based on Electron Beam Kernel Estimation
Authors: Kim Kwangrak , Cho Yunje , Cho Junghee , Park Jonghyeok , Wang Jeonghyun , Jeong Seunggyo , Lee Jubok , Hwang Yun , Kim Jiwoong , Yu Jeongwoo , Jung Heesu , Park Hyenok , Shon Subong , Jo Taeyong , Lee Myungjun
Published: January 2024

Scanning Electron Microscopy (SEM) leverages electron wavelengths for nanoscale imaging. Achieving optimal imaging requires precise adjustment of parameters like focus, stigmator, and aperture alignment, and therefore a process traditionally relies on skilled personnel and time-consuming adjustments. Existing auto-focus (AF) and auto-stigmation (AS) methods face challenges due to the interdependent nature of these parameters and sample diversity. This paper introduces a novel beam kernel estimation method, designed to independently optimize SEM parameters, irrespective of sample variations. Our approach disentangles the mutual influences among parameters, enabling concurrent optimization of focus, stigmator x, y, and aperture-align x, y. This method demonstrates robust performance, yielding average errors of 1.00µm for focus, 0.30% for stigmators, and 2.28% for aperture alignment, significantly outperforming the sharpness-based approach with its average errors of 6.42µm for focus and 2.32% for stigmators, and lacking in aperture-align capabilities. The key innovation of our approach lies in its ability to address the complex interplay of SEM parameters through a blind deconvolution model, facilitating rapid and automated optimization. This advancement not only enhances the precision and efficiency of SEM operations but also broadens its applicability across various scientific and industrial fields.
Quantitative DigitoGraphy: a Comprehensive Real-Time Remote Monitoring System for Parkinson’s Disease
Authors: Hoffman Shannon , Schmiedmayer Paul , Gala Aryaman , Wilkins Kevin , Parisi Laura , Karjagi Shreesh , Negi Aarushi , Revlock Simon , Coriz Christopher , Revlock Jeremy , Ravi Vishnu , Bronte-Stewart Helen
Published: January 2024

People with Parkinson’s disease (PWP) face critical challenges, including lack of access to neurological care, inadequate measurement and communication of motor symptoms, and suboptimal medication management and compliance. We have developed QDG-Care: a comprehensive connected care platform for Parkinson’s disease (PD) that delivers validated, quantitative metrics of all motor signs in PD in real time, monitors the effects of adjusting therapy and medication adherence and is accessible in the electronic health record. In this article, we describe the design and engineering of all components of QDG-Care, including the development and utility of the QDG Mobility and Tremor Severity Scores. We present the preliminary results and insights from the first at-home trial using QDG-Care. QDG technology has enormous potential to improve access to, equity of, and quality of care for PWP, and improve compliance with complex time-critical medication regimens. It will enable rapid “Go-NoGo” decisions for new therapeutics by providing high-resolution data that require fewer participants at lower cost and allow more diverse recruitment.
Machine learning for catalyst design: data matters
Authors: Mendes Pedro , Vermeire Florence , Haute Thibaut Van , Thybaut Joris W.
Published: January 2024

Catalyst design via machine learning relies directly on models. This study
investigated to what extent those models and their output for catalyst design,
i.e. the key catalyst properties, depend on the data characteristics
such as volume, number of features, design space, correlation between features,
and experimental uncertainty. Both an in silico and an experimental
catalytic dataset were explored. All data characteristics proved to impact
either the model performance and/or the most important catalyst properties
recognized. Particularly, sufficiently large experimental datasets as well as
uncorrelated and well-designed experimental variables (i.e. catalyst or operating
conditions) are rare in literature, but not particularly difficult to obtain
in practice. Acquiring new data with the inferred characteristics would better
ensure sound models, even if case-specific investigations may also render
existing data as useful.
Supporting professionals in the use of N95 masks at the start of a COVID-19 pandemic: a quality improvement approach
Authors: Couture Camille , Lavoie Marie-Eve , Mauriello Katerine , Layani Geraldine
Published: January 2024

Background: At the beginning of the COVID-19 pandemic, healthcare professionals (HCP) faced many clinical uncertainties, due in part to the rapid evolution of knowledge about this disease and how to adequately protect themselves. The impact of a workshop alone on improving healthcare professionals’ (HCP) knowledge of the proper use of N95 masks at the beginning of the COVID-19 pandemic was unknown.
Objective:We aimed to describe the development and implementation of a workshop on the proper use of N95 masks in hospital and its impact on HCP knowledge.
Design: Quality improvement approach using a mixed-method, pre/post workshop design, based on the ADDIE instructional design framework.
Setting and participants: All HCP working in one hospital in an urban region (Laval, Canada) in April 2020 were eligible.
Intervention: Workshop content based on recommendations and procedures available at that time and validated by hospital microbiologists.
Main outcome measures: We assessed participants’ knowledge on using N95 masks by questionnaires, pre and post workshop.
Results: We elaborated the workshop content on and it was offered to HCP within one month. Of the 150 HCP who attended the 18 workshops, 69 completed the pre- and post-questionnaires. Most were women (88%) and nurses (59%). Participants’ knowledge increased after the workshop (24-85%) and their anxiety was subjectively reduced. Conclusion: Using a workshop to share the latest recommendations on the proper use of N95 masks increased HCPs’ confidence. The quality improvement approach allowed the flexibility and speed of action required in an urgent sanitary context.
MacErt Culture Media: A Cost-Effective Selective Media for Carbapenemase Producing Enterobacterales Surveillance
Authors: SOW Ousmane , CISSE Abdoulaye , NDIAYE Issa , NIANG Elhadj Aly , WANE Abdoul Aziz , FALL Cheikh , SAMBE Bissoume , Mohammed Nuredin Ibrahim , DIEYE Yakhya , SECK Abdoulaye
Published: January 2024

Culture media play a crucial role in the identification of bacterial pathogens. This study aimed to evaluate the performance of MacErt1 and MacErt2 culture media, for the selective detection of Carbapenemase-Producing Enterobacterales (CPEs).
MacErt1 and MacErt2 were formulated by supplementing MacConkey agar with 0.5 mg/L and 1 mg/L of ertapenem, respectively. The two media were assessed using a panel of 26 characterized Enterobacterales, including CPEs producing OXA-48, NDM, and KPC. Then, the media were employed under realistic conditions for the analysis of wastewater. For each wastewater sample, 10 ml were filtered, and the membrane was placed on MacErt agar, followed by overnight incubation. Subsequently, colonies underwent further examination. Antimicrobial susceptibility tests and Conventional PCR targeting oxa-48-like, ndm, kpc, vim, and imp were conducted on the colonies to assess carbapenem resistance genes presence.
MacErt1 exhibited excellent sensitivity (100%) for NDM, KPC, and OXA-48-like producers, while MacErt2 showed a sensitivity of 60% for OXA-48-like CPEs but maintained high sensitivity (100%) for NDM and KPC producers. MacErt1 and MacErt2 exhibited specificities for CPEs of 93% and 71%, respectively. The application of MacErt1 to wastewater samples yielded a sensitivity of 100% and a specificity of 83% for CPEs.
The study underscores the efficacy and cost-effectiveness of MacErt1 and MacErt2 culture media, in detecting CPEs. MacErt1 exhibits 100% sensitivity across all CPEs, with 83% specificity in wastewater samples. MacErt2, with a specificity of 93% and 100% sensitivity for NDM and KPC producers, emerges as an excellent choice when targeting these specific strains.
Analysis by TeloView® Technology Predicts the Response of Hodgkin’s Lymphoma to first line ABVD Therapy
Authors: Knecht Hans , Johnson Nathalie , Bienz Marc , Brousset Pierre , Memeo Lorenzo , Shifrin Yulia , Louis Sherif , Mai Sabine
Published: January 2024

Classic Hodgkin’s lymphoma (cHL) is a curable cancer with disease-free survival rate of over 10 years. Over 80% of diagnosed patients respond favorably to first line chemotherapy. However, 15-20% of patients experience refractory or early relapsed disease. To date, the identification of such patients is still not possible using traditional clinical risk factors. The three-dimensional (3D) telomere analysis has been shown to be a reliable structural biomarker to quantify genomic instability, inform on disease progression, and predict patients’ response to therapy in several cancers, particularly hematological disorders. The 3D telomere analysis previously also elucidated biological mechanisms related to cHL disease progression. Here we report results of a multicenter retrospective clinical study including 156 cHL patients. We used the cohort data as a training dataset and identified significant 3D telomere parameters suitable to predict individual patient outcome at point of diagnosis. Multivariate analysis allowed for developing a predictive model using four telomeric parameters as predictors, including the proportion of t-stumps (very short telomeres). The percentage of t-stumps was the most prominent predictor to identify refractory/relapsing cHL prior to the initiation of ABVD therapy. The model characteristics include AUC of 0.83 in ROC analysis, sensitivity, and specificity of 0.8 and 0.75 respectively.
Prevalence and Associated Factors of Chronic Diseases among University Academics
Authors: Khamaiseh Abdullah , Habashneh Sakhaa
Published: January 2024

Background
Chronic disease problems are globally, regionally, and locally on the rise, marking that non-communicable chronic diseases (NCCDs) are never again associated with wealth. NCCDs are to blame for 70% of the entire deaths in the whole world. This study aimed to assess the prevalence of and factors associated with chronic diseases among academics at Mutah University-Jordan.
Methods
A cross-sectional approach is used. The study sample consists of the all academics teaching in all faculties at Mutah University. A 2-part self-administered and structured questionnaire of the participants’ demographic data and the Sample Questionnaire Chronic Disease developed by Stanford Patient Education Research Center were distributed to collate data.
Results
The five conditions with the highest degree of prevalence among the participants were hypertension (19.6%), DM (17.5%), Rheumatoid (14.2%), Cardiac diseases (12.6%), and respiratory disorders (11.3%).
Conclusions
Smoking and being overweight were the major risk factors observed among academics and were more prevalent among men than women. Healthy lifestyle programs encouraging appropriate dietary habits and physical activity are strongly recommended in the universities.