bluuebunny/crossref_metadata_2025 huggingface dataset:
Patch Testing In Nepalese Population: A Single Center Study From Kathmandu, Nepal
Authors: Paudel Sushil , Pun Guma , Parajuli Niraj , Sharma Rabindra
Published: May 2019

Introduction: Patch testing is a diagnostic tool used in investigation to identify specific allergens in allergic contact dermatitis (ACD). It helps find the prevalence and the trends of contact sensitization in the community.

Objective: To report the two year patch test results from a central hospital in Kathmandu.

Materials and Methods: Consecutive consenting patients of suspected ACD were patch tested with an Indian standard Series (Systopic) from June 2014 to August 2016.

Results: Out of 141 patients tested, 89 were female (63.12%) and 52 were male (36.88%). Hand eczema was the commonest pattern (53 patients) followed by persistent and recurrent eczema (44 patients) and face eczema (25 patients). Fifty- five patients (39%) had at least 1 positive allergic reaction. Among these, 16.31% were male and 22.70% were female. The most common allergen was nickel sulfate (19.9%) followed by fragrance mix (7.8%) and paraphenyldiamine (PPD) (6.4%). Out of total positive cases 27 (21 females and 6 males) had shown strong positive reactions (++). The Nickel Sulfate was responsible in majority of cases (18/27 cases). Farmers had the highest (57.14%) rate of positive allergic reactions followed by housewives (39.62%). According to the regional eczema, patients with persistent and recurrent eczema of different parts of body had the highest rate of positive allergic reactions (47.72%). Almost half of patient with facial eczema (40%) had positive patch test.

Conclusion: Larger studies are required in the different parts of the country to find a more accurate data regarding the sensitization pattern in Nepalese population.
Pattern of Pediatric Dermatoses in a Tertiary Referral Centre, Nepal
Authors: Sharma Rabindra
Published: May 2019

Introduction: Dermatological problems constitute at least one third of all outpatient visits to a pediatrician and similar number of all visits to a dermatologist involve children.Children are often exposed to climatic and social conditions that make them more likely to develop skin infections and skin injuries.Little is known about the impact of pediatric skin disease on health care systems in developing countries like Nepal. So, data on this study can be useful in monitoring changes in disease trends in children and planning health care programs.

 

Objectives: To know the current status of disease trends and ethnic distribution of common dermatoses among children (hospital  based) in this geographical locality.

 Materials and Methods: All children, 14 years and below, attending the dermatology out-patient department with any dermatoses were  enrolled in the study. The diagnosis was made by dermatologists based on detailed history and appropriate investigations. Patients were divided into four different age groups.

Results: A total of 424 children with skin related symptoms were enrolled in this study. The mean age of this population was 6.30 years and it ranged from 0.05(19 days) to14 years. A total of 146 infective and 278 non-infective dermatoses were encountered as the primary diagnosis. Infections and infestations were the most common group of disorders (34.4%, 146 cases), followed by dermatitis and eczemas (32.5%, 138 cases). Fungal infections were the most common infective conditions (11.6%, 49 cases).

Conclusion: Infections and infestations were the most common etiologic group of disorders followed by dermatitis and eczemas. Fungal infections were the most common infective conditions followed by pyoderma.
Upcoming Therapeutic Modalities for the Treatment of Keloids: An Update
Authors: Keyal Uma , Bhatta Anil Kumar
Published: May 2019

Introduction: Keloids are benign dermal tumors that generally form by local fibroblast proliferation and excessive collagen production following skin trauma. Several methods have been described for the treatment of keloid, often with suboptimal results and recurrences.

Objective: To update literature that provides information regarding upcoming therapeutic modalities for the treatment of keloids, including lasers, radiofrequency (RF), photodynamic therapy (PDT), and ultraviolet A1 (UVA1) irradiation.

Materials and Methods : A systematic review of the literature was performed for the original articles related to the treatment of keloids. The search terms ‘keloids’ and ‘lasers’ or ‘radiofrequency’ or ‘PDT’ or ‘UVA1’ was entered into a search of the National Library of Medicine’s PubMed Database.

Result: The search returned a total of 188 sources, of which, 26 articles met our inclusion criteria.

Conclusion: Combination approach is superior than solo therapy in the treatment of keloid. However, it is highly desirable that new emerging therapies undergo large-scale studies with long-term follow-up before being recommended conclusively as alternative therapies for the treatment of keloid. Moreover, lack of randomized clinical trials (RCTs) needs to be taken into consideration urgently.
Uma perspectiva analítico-comportamental do desenvolvimento
Authors: Schlinger, Jr. Henry D.
Published: May 2019

In this article, I describe how my behavior-analytic perspective on infant and child development evolved andwhat a behavior-analytic theory of development might look like. I begin by describing how my approach toteaching child development courses changed from focusing mostly on behavior analysis to teaching criticalthinking skills that would enable students to evaluate traditional developmental research and theory and thento find a behavior-analytic perspective more appealing. I describe the critical thinking skills I teach students,including nominal fallacy, circular reasoning, reification, and parsimony. Throughout, I contrast a traditionaldevelopmental approach to research and theory with a behavior-analytic approach. In particular, I notedifferences between the between-subjects experimental designs used by developmental researchers and thewithin-subjects experimental designs used by behavior analysts in terms of internal and external validity andtheir implications for theory construction. I argue that, because behavior-analytic theory is inductively derivedfrom decades of experimental analysis, it is in a better position to achieve the goals of prediction, control, andunderstanding and can generate successful technologies of behavior change.
Ultrasound guided bilateral erector spinae plane block for post-surgical pain in patients after thoracic surgery
Authors: Dmytriiev D V , Glazov E O , Marchuk O V , Zaletskiy B V
Published: May 2019

Objective: To examine the analgesic efficacy of bilateral erector spinae plane (ESP) block compared with conventional treatment for pain after thoracic surgery.

Methods: 34 patients with thoracic trauma were divided into 2 groups. Patients in group 1 (ESP block group, n = 14) received ultrasound-guided bilateral ESP block with 3 mg/kg of 0.375 % ropivacaine before anesthesia induction at the T6 transverse process level (Fig. 1). Patients in group 2 (acetaminophen and morphin group, n = 20) received acetaminophen (15 mg/kg every 6 hours – maximum 1 g) and morphine (10 mg every 8 hours) intravenously in the postoperative period. The primary study outcome was to evaluate pain at rest using a 10-point numeric rating scale (NRS). Mann – Whitney U-test was used for comparing NRS scores.

Results: The postoperative pain level after extubating and duration of analgesia during which NRS was < 4 of 10 was compared be-tween the groups. The median pain score at rest after extubating in group 1 was 0 of 10 until hour 6, 3 of 10 at hour 8, and 4 of 10 at hours 10 and 12 postextubation. These were significantly less in comparison with group 2 (p = 0.0001). Patients in group 1 had a significantly higher mean duration of analgesia (11.04 ± 0.18 hours), during which NRS was < 4 of 10, compared with group 2 (4.18 ± 0.14 hours) (p = 0.0001). Conclusion: ESP block safely provided significantly better pain relief at rest for longer duration as compared to intravenous acetaminophen and morphine.
Радіочастотна деструкція та лазерна деструкція тригерних точок у лікуванні міофасціального синдрому
Authors: Леонтьєв О Ю , Назаренко О С
Published: May 2019

Актуальність. Міофасціальний синдром (МФС) – це хронічний больовий синдром, який виникає у м’язах і проявляється однією або кількома тригерними точками. МФС діагностується у 88 % пацієнтів, які звернулися з болем у спині.

Мета. Оцінка ефективності радіочастотної деструкції (РЧД) та лазерної деструкції (ЛД) у лікуванні міофасціального синдрому.

Матеріали та методи. Відібрано пацієнтів з МФС, проліковані в нейрохірургічному відділенні ХОКЛ у 2016 р. – 2019 р. Всього 77. Розділено на 2 групи: 1 – пацієнти, яким проводилась РЧД, – 53 пацієнтів (жінок – 37, чоловіків – 16), середній вік 54,4 р. Після пробних блокад з анестетиками виконувалась РЧД апаратом Radionics RFG-3C 1–2 сесії. 2 група – пацієнти, яким проводилась ЛД, – 24 пацієнтів (жінок – 16, чоловіків – 7), середній вік 49,85 р. Після пробних блокад з анестетиками виконувалась процедура ЛД апаратом Ліка-хірург.

Результати лікування. Оцінка проводилась при госпіталізації та виписці за шкалами Освестрі, ВАШ, Проло. 1 група при госпіталізації Освестрі 18–91,1 (середнє 55,07), ВАШ 4–10 (середнє 7,6), Проло 2–8 (середнє 4,2), при виписці Освестрі 0–78 (середнє 28,26), ВАШ 0–8 (середнє 2,5), Проло 2–9 (середнє 6,3). 2 група Освестрі 26–86,6 (середнє 51,6), ВАШ 4–10 (середнє 6,08), Проло 2–7 (середнє 4,6), при виписці Освестрі 0–60 (середнє 25,05), ВАШ 0–4 (середнє 2,12), Проло 3–10 (середнє 6,7). Проведено статистичний аналіз шляхом множинної регресії. При порівнянні в обох групах покращення за Освестрі 26,11 в середньому, стандартне відхилення (СВ) 14,8, за ВАШ 4,77 в середньому, СВ 2,2, за Проло 2,29 в середньому, СВ – 1,57. Покращення за ВАШ (р = 0,000 002) та Проло (р = 0,005) статистично достовірні. За Освестрі (р = 0,8). Недоліки аналізу: не враховувались стать пацієнтів, тривалість хвороби. Рецидивів протягом 1–3 років не було.

Висновки:

Методи РЧД та ЛД статистично достовірно покращують стан пацієнтів з МФС.

Статистичної різниці у результатах лікування у групах РЧД та ЛД не виявлено, але потрібні детальніші дослідження. Перспективи подальших досліджень. За даними цього дослідження, методи однаково ефективні. Однак потрібні додаткові дослідження кожного методу.

Конфлікт інтересів. Відсутній.
Le manager face aux paradoxes du changement
Authors: Rieu Plichon Caroline
Published: May 2019

Le changement produit incertitude et paradoxes, que les managers ont pour mission de gérer. La littérature en management recommande de réduire l’incertitude et d’éclaircir les paradoxes, en mobilisant des aptitudes reflétant une capabilité dite positive. Cet article1 explore une autre voie pour gérer le changement, par le concept méconnu de capabilité négative – une aptitude à rester dans les doutes et l’incertitude (Keats, 1970) et propose une grille d’analyse de ces capabilités opposées. Par la capabilité négative, nous souhaitons réhabiliter le management de l’incertitude – et non sa minimalisation – dans les organisations.
Wunderlich's syndrome as the fatal complication of a renal angiomyolipoma: a case report and review of the literature
Authors: ARSLAN Fatma Zeynep , ALTUNKESER Ayşegül
Published: May 2019

Wunderlich
syndrome (WS) is a rare acute abdominal condition, which is  characterized with spontaneous nontraumatic
renal haemorrhage into the subcapsular and perirenal spaces. Renal cell
carcinoma, angiomyolipoma, renal cysts, vasculitis or blood dyscrasias are
among the known risk factors. We
report a case of Wunderlich's syndrome in an 59 year old woman associated with
massive retroperitoneal hemorrhage.
Sistem Pendukung Keputusan Pemilihan Media Cetak Sebagai Sarana Promosi Menggunakan Metode Analytical Hierarchy Process Dan Weighted Product
Authors: Gunawan Gunawan
Published: May 2019

The selection of advertising media in the development and business competition is very important. It determines that criteria and the alternative for each person is different. It makes decisions are very difficult because we have a lot of choices, time and cost.Decisions that are fast and appropriate in determining the best print media as a promotion, which is in accordance with the needs and desires of the advertiser.Selection of Analytical Hierarchy and Weighted Product (WP) method as a tool to assist in making decisions with calculations done by using AHP to get criteria weight and continue using the WP method. Both methods can provide recommendations in the selection of print media as a medium of promotion. The result of combining the two methods results in a rankingKeywords : Analytical Hierarchy Process    Weighted Product, media print
Biological activities of spike moss Selaginella tamariscina (Beauv.) Spring. collected from Co Thach, Binh Thuan
Authors: Do Tran Ngoc Bao , Le Tien Thi My , Dinh Hiep Minh , Quach Phuong Ngo Diem
Published: May 2019

In Vietnam, Selaginella tamariscina (Beauv.) Spring. has been used as a traditional medicine for osteoarthritis, haemorrhage, hepatitis, burn, … However, Selaginella tamariscina is less studied than in other countries. Therefore, this research focuses on study some bioactivities (such as antioxidative, antibacterial activities, and inhibition of albumin denaturation) and preliminary phytochemical screening of six extracts (ethanol extracts of root, leaf, whole plant, petroleum extracts of root, leaf, whole plant) of S. tamariscina collect from Co Thach, Binh Thuan Province. The preliminary phytochemical screening results show that Selaginella tamariscina extracts have most of secondary metabolite groups such as phenolics, alkaloids, flavonoids, steroids, and lactone. The antibacterial activity of the ethanol extract of root is higher than that of other extracts. Moreover, the ethanol extract of root also has the highest reducing ability and free radical scavenging activity, with EC50 = 1.590 ± 0.091mg/ml. In the anti-denaturation of albumin test, the petroleum ether extract of whole plant has the lowest IC50 at 99 ± 5μg/ml.
Isolation of Streptococcus mutans causing cavities and study of the inhibition of this bacteria by some common medicinal plants
Authors: Luu Lat Hong , Le Vuong Duong , Phan Trang Thi Phuong
Published: May 2019

The aim of this study is the selection of some folk medications which can inhibit the Streptococcus mutans causing cavities. The authors isolated 139 strains from 153 dentin caries collected at the National Hospital of Odonto- Stomatology in HCM City. Based on the characteristic colonies on the MSB selective medium (Mitis Salivarius Agar supplemented with sucrose and bacitracin), resulting of stained Gram and biochemical assay, there are 66 strains of S. mutans. Examination of antimicrobial resistance levels of 66 isolates and S. mutans ATCC 25175 (control) isolates and tested seven common plants in folk such as Eichchornia crassipes, Polygonum aviculare, Sauporus androgynus, Phyllanthus urinaria, Pogostemon cablin, Areca catechu and Camellia sinensis proable antimicrobial. The results showed that Polygonum aviculare had the highest antibacterial activity against S. mutans and its chloroform extract show the strongest effect.
Theoretical study on structures and electronic properties of Na8TM clusters (TM = Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn)
Authors: Nguyen Hong Van , Nguyen That Van , Le Bong Thi , Do Huong Thi Thanh , Huynh Truc Thi Thanh
Published: May 2019

Na8TM (TM = Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn) clusters are optimized by DFT calculations combining the Triple zeta valence plus polarization (TZVP) method to determine magnetic torque values on orbits, point groups, electron structures, and spin density images of the atomic groups. The results indicate that Na atoms in Na8TM cluster strongly affect the total magnetic moment of the whole group of atoms. In a cluster, each Na atom contributes one electron which combines with valence electron of transition metal for creating a sum of valence electron of the cluster. Atomic groups with the highest magnetic moments are Na8V (5 B) and non-magnetic clusters are Na8Ni and Na8Zn. The electronic structure and magnetic properties of the clusters resemble those of some metals and transition metal ions. This study will orientate to substitution in magnetic materials by metal clusters.
Consensus Integrase of a New HIV-1 Genetic Variant CRF63_02A1
Authors: Agapkina Yu. Yu. , Pustovarova M. A. , Korolev S. P. , Zyryanova D. P. , Ivlev V. V. , Totmenin A. V. , Gashnikova N. M. , Gottikh M. B.
Published: May 2019

The high genetic variability of the human immunodeficiency virus (HIV-1) leads to a constant emergence of new genetic variants, including the recombinant virus CRF63_02A1, which is widespread in the Siberian Federal District of Russia. We studied HIV-1 CRF63_02A1 integrase (IN_CRF) catalyzing the incorporation of viral DNA into the genome of an infected cell. The consensus sequence was designed, recombinant integrase was obtained, and its DNA-binding and catalytic activities were characterized. The stability of the IN_CRF complex with the DNA substrate did not differ from the complex stability for subtype A and B integrases; however, the rate of complex formation was significantly higher. The rates and efficiencies of 3-processing and strand transfer reactions catalyzed by IN_CRF were found to be higher, too. Apparently, all these distinctive features of IN_CRF may result from specific amino acid substitutions in its N-terminal domain, which plays an important role in enzyme multimerization and binding to the DNA substrate. It was also found that the drug resistance mutations Q148K/G140S and G118R/E138K significantly reduce the catalytic activity of IN_CRF and its sensitivity to the strand transfer inhibitor raltegravir. Reduction in sensitivity to raltegravir was found to be much stronger in the case of double-mutation Q148K/G140S.
Isolation, Purification and Characterization of L,D-transpeptidase 2 from Mycobacterium tuberculosis
Authors: Baldin S. M. , Shcherbakova T. A. , Švedas V. K.
Published: May 2019

L,D-transpeptidase 2 from Mycobacterium tuberculosis plays a key role in the formation of nonclassical 3-3 peptidoglycan cross-links in a pathogens cell wall making it resistant to a broad range of penicillin antibiotics. The conditions of cultivation, isolation, and purification of recombinant L,D-transpeptidase 2 from M. tuberculosis have been optimized in this study. Oxidation of the free SH groups of catalytic cysteine Cys354 is an important factor causing the inactivation of the enzyme, which occurs during both the expression and storage of enzyme preparations. The biochemical characteristics of purified L,D-transpeptidase 2 and L,D-transpeptidase 2 lacking domain A were determined; the kinetic constants of enzyme-catalyzed nitrocefin transformation were evaluated.
Thermodynamics of the DNA Repair Process by Endonuclease VIII
Authors: Kladova O. A. , Kuznetsov N. A. , Fedorova O. S.
Published: May 2019

In the present work, a thermodynamic analysis of the interaction between endonuclease VIII (Endo VIII) and model DNA substrates containing damaged nucleotides, such as 5,6-dihydrouridine and 2-hydroxymethyl-3-hydroxytetrahydrofuran (F-site), was performed. The changes in the fluorescence intensity of the 1,3-diaza-2-oxophenoxazine (tCO) residue located in the complementary chain opposite to the specific site were recorded in the course of the enzyme-substrate interaction. The kinetics was analyzed by the stopped-flow method at different temperatures. The changes of standard Gibbs free energy, enthalpy, and entropy of sequential steps of DNA substrate binding, as well as activation enthalpy and entropy for the transition complex formation of the catalytic stage, were calculated. The comparison of the kinetic and thermodynamic data characterizing the conformational transitions of enzyme and DNA in the course of their interaction made it possible to specify the nature of the molecular processes occurring at the stages of substrate binding, recognition of the damaged base, and its removal from DNA.
Membina Kemampuan Kepala Sekolah dalam Melakukan Evaluasi dan Pelaporan Pelaksanaan Program Kegiatan Sekolah melalui Supervisi Manajerial di Wilayah Kepengawasan Gugus Sekolah 03 Kecamatan Prajuritkulon dan Gugus Sekolah 01 Kecamatan Kranggan Kota Mojoker
Authors: Sunarijah Sunarijah
Published: May 2019

In this global era, the ability of schools to change depends on their capacity to learn ... Principals, for example, must comply with various system requirements and manage routine administrative tasks. The principal is required to be able to evaluate and report on the implementation of school activities. The purpose of this study are: Describe the ability of the principal in evaluating and reporting the implementation of school activity programs in the field of Work Programs, Regulations and Decisions, Guidance, Other Administration through managerial supervision in School Cluster Monitoring Areas 03 Prentarakulon District and School Clusters 01 Kranggan District Mojokerto City . This research uses action research as many as two cycles. Each cycle consists of one meeting, each meeting consisting of four stages: design, activities and reflection and revision observations. The target of this research is the Principal in the School Cluster Monitoring Area 03 of the Prentarakulon and School Cluster 01 District of Kranggan, Mojokerto City with 12 people. Data obtained in the form of managerial supervision results which include: Work Programs, Regulations and Decisions, Guidance, Other Administration. The success of the learning process in cycle II shows that the cycle can be stopped because it has met the target of> 80%. This is evident from the average increase in the performance of principals from 72.70% in the initial conditions, increasing to 78.92% in the first cycle and increasing to 87.81% in the second cycle. The conclusions of this research are: 1) The principal can evaluate and report on the implementation of the school activity program in the Field of Work Program through managerial supervision. 2) Principals can evaluate and report on the implementation of school activities in the field of Regulations and Decisions through managerial supervision. 3) The principal can evaluate and report on the implementation of school activities in the field of guidance through managerial supervision. 4) The school principal can evaluate and report on the implementation of other administrative activities in the school administration program through managerial supervision
Pengaruh Enabling environment, Knowledge infrastructure, Human and physical resource terhadap Kemampuan Mengajar Semester Akhir dengan Variabel antara School Management and Governance pada Program studi Pendidikan Agama Islam Sekolah Tinggi Ilmu Tarbiyah
Authors: Ashar Salim
Published: May 2019

The success of teaching learning depends on; (1) Enabling environment; (2) Knowledge infrastructure; (3) Human and physical resources, and (4) school management and governance. Finally, the above is determined by an education policy. The objectives of this study are: 1) To find out and analyze the influence of Enabling environment on school management and governance. 2) To find out and analyze the influence of Knowledge Infrastructure on school management and governance. 3) To find out and analyze the influence of Human and physical resources on school management and governance. 4) To find out and analyze the effect of the Enabling environment on the ability to teach in the final semester. 5) To find out and analyze the influence of Knowledge infrastructure on the ability to teach in the final semester. 6) To find out and analyze the influence of Human and physical resources on the ability to teach in the final semester. 7) To find out and analyze the influence of school management and governance on the ability to teach in the final semester. 8) To find out and analyze the direct influence of Enabling environment, Knowledge infrastructure and Human and physical resources on the ability of final semester teaching through variables between school management and governance. Based on the consideration of time, energy, and funds, as well as the scope of the problem and the large number of subjects in a population of 53 people, this study uses census research. Where all members of the population are sampled. The results of the study can be summarized as follows: 1) Enabling environment does not have a significant effect on school management and governance. 2) Knowledge infrastructure has a significant effect on school management and governance. 3) Human and physical resources have a significant effect on school management and governance. 4) Enabling environment has a significant effect on the ability to teach in the final semester. 5) Knowledge infrastructure has a significant effect on the ability to teach in the final semester. 6) Human and physical resources have no significant effect on the ability to teach in the final semester. 7) School management and governance have no significant effect on the ability to teach in the final semester. 8) Enabling environments, Knowledge infrastructure and Human and physical resources each directly influence the ability of final semester teaching through variables between school management and governance
An innovated integrated model using Singular Spectrum Analysis and Support Vector Regression optimized by intelligent algorithm for rainfall forecasting
Authors: Li Weide , Zhang Juan
Published: May 2019

Rainfall forecasting is becoming more and more significant and precipitation anomalies would lead to droughts and floods disasters. However, because of the complexity and non-stationary of rainfall data, it is difficult to forecast. In this paper, a novel hybrid model to forecast rainfall is developed by incorporating singular spectrum analysis (SSA) and dragonfly algorithm (DA) into support vector regression (SVR) method. Firstly, SSA is used for extracting the trend components of the hydrological data. Then, SVR is utilized to deal with the volatility and irregularity of the precipitation series. Finally, the parameter of SVR is optimized by DA. The proposed SSA-DA-SVR method is used to forecast the monthly precipitation for Songbai, Panshui, Lanma and Jiulongchi stations. To validate the efficiency of the method, four compared models, DA-SVR, SSA-GWO-SVR, SSA-PSO-SVR, SSA-CS-SVR are established. The result shows the proposed method has the best performance among all five models, and its prediction has high precision and accuracy.
Centro antifumo UOC Ser.D (Asp di Cosenza): Storia di una esperienza decennale
Authors: Calabria Roberto , Rota Amerigo Giuseppe , De Simone Alessandro
Published: May 2019

Il Centro Antifumo (Centro Trattamento Tabagismo - CTT) è stato istituito dall'ASP di Cosenza (Regione Calabria) presso la U.O.C. Ser.D di Cosenza nel mese di luglio dell'anno 2008 e compie quindi 10 anni di attività. In questo articolo si restituisce il report di una esperienza decennale che è riuscita ad ottimizzare un percorso di cura efficace e singolare che ha consentito di raggiungere negli anni alte percentuali di successi terapeutici.
Gli outcome nel trattamento dell'alcoldipendenza. L'esperienza del SA di piazza Montale – Torino
Authors: Sciutteri Bruno , Tortia Bruno , Bignamini Emanuele
Published: May 2019

Lo studio riguarda i dati clinici di efficacia dei trattamenti dell'utenza in carico al Servizio di Alcologia (SA) del Dipartimento Dipendenze Torino Nord nell'anno 2016. A fronte di un'utenza complessiva afferente al servizio nell'intero anno 2016   corrispondente a 212 utenti, i dati di efficacia verificati riguardano 144 pazienti per i quali sono stati individuati e verificati 236 obiettivi di cui 132 sanitari e 104 psico-socio-educativi (pse). La valutazione di efficacia viene espressa percentualmente, a seconda del grado di realizzazione, in obiettivi realizzati, parzialmente realizzati e non realizzati. L'efficacia del SA è quasi sovrapponibile a quella dei SerD in assenza di farmaco agonista. Il dato di efficacia degli obiettivi sanitari è significativamente superiore a quello degli obiettivi pse, tuttavia  bisogna considerare che il trattamento pse richiede  un "cambiamento" della persona  più "realizzativo", inevitabilmente meno efficace nel breve termine, ma potenzialmente determinante nel lungo periodo.
Terapia di gruppo: il setting gruppale nel trattamento delle dipendenze
Authors: Algisi Pietro
Published: May 2019

The development and maturation of group intervention techniques have conferred more and more to grouptherapy the characteristics of an effective intervention technique on many pathologies and from the ‘70s therehas been a progressive application of this technique to the specific field of addiction therapy with a growing consensusby specialists for the positive outcomes supported by scientific literature.Also in Italy, the use of this work tool is a reality that is characterizing more and more the practice in differentclinical areas of addiction and group intervention has become one of the main therapeutic resources of outpatientand hospital team for the wide range of possible strategies and for the high number of patients that is possibleto treat effectively, combining the criteria of efficacy and of efficiency.This article highlights the specific processes and dynamics of psychodynamic oriented psychotherapeutic grouptreatment, which aims to develop a better self-protective ability not only trough the identification and experimentationof new psyco-behavioural strategies different from the dysfunctional ones of substance abuse but alsotrough the acquisition of instruments and resources to find your own "welfare system", affective, emotional,physic and mental, and to try to keep it in balance as much as possible
Implementation of Problem Formulation Management in Improving the Quality of Research in Higher Education
Authors: Nirmalasari Leli , Harahap Eka Purnama , Faradilla Fitri
Published: May 2019

Basically in conducting a study there are problems that can be used as a means toachieve a goal or goal in the study. Everyone who conducts research must have their ownmethod, concept, or method in formulating the problem that is the object of the research. In thispaper will explain the techniques or ways that can be done in relation to formulating problems inresearch including determining a topic to be discussed in research, making backgroundproblems, explaining problem identification, limiting the scope of research, determiningproblems that are worthy of research, making questions in research, and determine the goals,benefits, and uses of the research. With the concept of planning and mature thinking toformulate and determine the formulation of the problem, it is expected that the research that willbe conducted will be focused and directed so that it does not extend to the discussion that is notthe topic of his research. With the formulation of this problem also the reader becomes aware ofthe results and objectives to be conveyed in a study. Therefore in this study we will discuss thesteps or ways in preparing the formulation of a problem that is good and right in order tofacilitate the implementation of a research activity.
The Effect of Rinfogroups as a Discussion Media in Student Learning Motivation
Authors: Rahardja Untung , Aini Qurotul , Khoirunisa Alfiah
Published: May 2019

In the current era of globalization, technology management has touched every aspect of human life. The combination of these two factors will become an innovation in the management of education. At Raharja College, the entire academic community has facilities in the form of an official e-mail, namely Information which functions as a communication medium. However, there is no place for discussion management between students and lecturers, so that the discussion process of learning is considered to be ineffective and inefficient because it is still done directly. Therefore, it is necessary to optimize the use of RinfoApps which is used as a discussion medium for online learning. RinfoGroups is one of the Google System features that can be used as a formal media for the online learning discussion management process. By creating a forum called the class mailing list at RinfoGroups, students and lecturers can discuss anytime, students can share about learning material, and lecturers can also monitor the effectiveness of student discussions, this certainly has a significant influence on student learning motivation. Supported by 2 (two) research methods, namely library research and observation methods. The final results of the research that has been achieved are the formation of a discussion media that is easily accessible anywhere and anytime so that the discussion process between students and lecturers becomes more effective and efficient.

Keywords: Rinfogroups, Media Communication, Students, Discussion
Pemanfaatan Google Scholar Dan Citation Dalam Memenuhi Kebutuhan Pembuatan Skripsi Mahasiswa Pada Perguruan Tinggi
Authors: Rahardja Untung , Tiara Khanna , Rosalinda Iis Ariska
Published: May 2019

Pada perkembangan teknologi saat ini, menulis dokumen secara digital sudah banyak dilakukan oleh para mahasiswa. Namun, mencari sumber referensi yang sah dan mengetahui apakah tulisan tersebut mengandung unsur plagiarism atau tidak masih mengalami banyak  kendala. Selama ini terkadang para mahasiswa masih banyak yang mencari referensi dari sumber yang belum terpercaya, padahal hal tersebut dapat menjadi hal yang sangat fatal untuk penulisan laporan Tugas Akhir (TA) dan Skripsi. Oleh karena itu Google mensupport dengan adanya sistem google scholar sebagai sumber informasi dan referensi yang sah. Selain google scholar, Google pun mensupport dengan pembuatan Citation (Daftar Pustaka),yang k ita ketahui selama ini membuat daftar pustaka dilakukan dengan cara  manual. Karena  perkembangan  jaman  Google  kembali mensupport  pembuatan  data menggunakan citation dengan terkomputerisasi oleh sistem. Pada penelitian ini menggunakan metode mind  mapping dan analisa SWOT. Diharapkan dengan adanya penelitian ini mahasiswa mampu membuat laporan Tugas Akhir (TA) dan Skripsi menemukan referensi yang lebih luas dan dapat memudahkan para penguji sidang menemukan plagiarism pada laporan Tugas Akhir dan Skripsi  yang dibuat oleh mahasiswa.

Kata kunci : Skripsi, Google Scholar, Citation

On development of current technologies, writing documents digitally has been done by the students. However, finding a legitimate reference source and find out whether the text contains elements of palgiarism or not still encountered many constraints. During this time the students sometimes still mecari references  from  sources  that  have not been reliable, but it can be very fatal for the final project  report  writing  (TA)  and  Thesis.  Therefore  Google  support  by  having  the  system  google scholar as a source of information and reference. In addition to google scholar, Google any support with the creation of Citation (bibliography), which we know as long as it mak es the references done by manual. Because of the changing times Google returns support creation of data using the citation with a computerized system. On the research method using mind mapping and SWOT analysis. It is hoped this research with the students are able to make the final project reports (TA) and Thesis find a broader reference and can facilitate the trial examiners find final project reports on plagiarism and Thesis made by students.

Keywords : Thesis, Google Scholar, Citation
Penerapan Sistem Autentikasi Sertifikat Sebagai Pengambil Keputusan Validasi Sertifikat Pada Perguruan Tinggi
Authors: Rahardja Untung , Harahap Eka Purnama , Fresandy Gilang
Published: May 2019

Pengembangan sistem adalah suatu cara untuk memberikan inovasi terbaru pada Perguruan Tinggi  dimana  sistem  yang  dibuat  harus  berdasarkan  apa  yang dibutuhkan para Pribadi Raharja. Autentikasi sertifikat dimaksudkan untuk  melengkapi dan mengoptimalkan Validasi Sertifikat pada PO Sidang, salah satunya terdapat poin Validasi Sertifikat dan Tridharma. Mahasiswa harus melakukan validasi dengan cara submit via website dan akan di review oleh admin.  Dengan  hadirnya  autentikasi  sertifikat  ini  admin  bisa  mengecek   keaslian  dari sertifikatnya dimanapun dan kapanpun. Dan sertifikat akan terdokumentasi dengan baik  di dalam database. Jadi admin bias lebih baik  lagi dalam melakukan validasi dan mengurangi potensi pemalsuan sertifikat.

System development is a way to provide the latest innovations in Higher Education where the system  created  must  be  based  on  what  is  needed  by  Personal  Raharja. Certificate authentication for Structure and optimal Validation of Certificates on PO Session, one of the points. Certificate Validation and Tridharma. Students must validate by submitting via website and will be reviewed by admin. With the presence of this certificate authentication admin can check the authenticity of the certificate wherever and whenever. And certificates will be well documented in the database. So admin bias is better in validating and reducing the potential for certificate forgery.
Penerapan Dashboard Sebagai Media Pengumpulan Data Laporan Penulisan Mahasiswa di Widuri Menggunakan Rinfo Spreadsheet Pada Perguruan Tinggi
Authors: Handayani Indri , Kurniati Dian , Yakin Saeful Aenul
Published: May 2019

Dashboard adalah satu aplikasi yang secara real time akan memonitoring berbagai informasi yang dibutuhkan oleh suatu organisasi atau perusahaan dengan berbagai macam format. Dengan adanya perkembangan teknologi informasi yang canggih, saat ini Widuri yang merupakan salah satu website yang ada di Perguruan Tinggi Raharja ternyata belum menerapkan dashboard pada website tersebut sehingga menyulitkan para admin widuri dalam merekap laporan performa widuri wayang. Maka diperlukannya penerapan dashboard pelaporan penulisan Widuri pada Website Widuri dengan menggunakan mediawiki yang bisa menampung dan mengolah data untuk dijadikan sebuah informasi yang dibutuhkan.

Kata kunci : Dashboard, Widuri, Informasi Dashboard is an application that in real time will monitor various information needed by an organization or company with various formats. With the development of sophisticated information technology, this time Widuri is one of the websites in the College Raharja was not yet apply the dashboard on the website so difficult for the administrators of widuri in recording performance reports puppet widuri. So the need for the application of dashboard reporting Widuri writing on Widuri Website by using mediawiki that can accommodate and process data to be a needed information.

Keywords: Dashboard, Widuri, Information
Video Company Profile LIVE Kota Tangerang Dengan Teknik Editing Menggunakan Adobe Premier Pro
Authors: Handayani Indri , Setiadi Ade , Ramadani Rizki
Published: May 2019

Kota Tangerang adalah wilayah baru hasil dari perkembangan Kabupaten Tangerang provinsi Banten. Kota Tangerang berkembang dan menunjukan diri sebagai kota metropolitan penyangga ibu kota Jakarta. Pemerintah Kota Tangerang memiliki program besar membangun kota layak huni, layak investasi, layak dikunjungi, dan kota cerdas yang saat ini kenal dengan Tangerang Liveable, Investable, Visitable, E-City (LIVE). Tujuan dari penelitian ini adalah memperkenalkan program pemerintah Kota Tangerang. Manfaat dari penelitian ini adalah sebagai media informasi dan promosi. Metode yang digunakan yaitu dengan cara observasi lapangan dan studi pustaka. Pendekatan masalah yaitu membuat analisa, story board, pengambilan gambar, proses pengeditan video dan rendering. Dalam pembuatan video ini menggunakan software Adobe Premier Pro CC 2018 dan hasil dari video profile program Kota Tangerang LIVE dibuat dalam format mp4 kemudian diupload dalam social media youtube dengan tujuan dapat dilihat oleh masyarakat luas, khususnya warga Kota Tangerang.

Kata kunci: Kota Tangerang, LIVE, Video Profile
Optimalisasi Informasi Manajemen Laporan Assignment Pada Website Berbasis Content Management System
Authors: Rahardja Untung , Aini Qurotul , Apriani Desy , Khoirunisa Alfiah
Published: May 2019

Seperti yang kita ketahui saat ini , Indonesia sudah memasuki era revolusi 4.0 yang mana pada era tersebut memiliki pengaruh besar terhadap perubahan yang terjadi di semua bidang. Termasuk dalam bidang pendidikan khususnya, perubahan yang terjadi di dunia pendidikan saat ini begitu pesat dengan ditinggalkannya metode belajar yang masih menggunakan cara konvensional. Mengerjakan tugas dengan buku, komunikasi tatap muka, mengumpulkan assignment dalam bentuk hardcopy, yang tentunya akan menyebabkan banyak kerugian dalam jangka waktu tertentu, seperti banyak assignment yang lama tertimbun dan sulit untuk ditemukan ketika dibutuhkan. Metode tersebut tentunya dianggap sebagai cara yang membosankan dan membuang banyak waktu, di mana mahasiswa tidak dapat mengeksplorasi dalam proses pembelajaran yang akan memakan waktu lama untuk melakukan pencarian manual untuk jumlah file yang telah dikumpulkan. Pada saat ini penerapan metode pembelajaran dengan konsep menata banyak laporan pengerjaan assignment dalam sebuah website content management system. Metode pembelajaran ini dibuat untuk memaksimalkan cara menata laporan assignment mahasiswa guna efisiensi manajemen waktu, oleh karena itu metode pembelajaran ini dapat diterapkan sebagai manajemen pendidikan di pendidikan tinggi. Diharapkan dengan adanya metode ini dapat meningkatkan manajemen waktu dalam belajar sehingga memotivasi untuk mengeksplorasi kemampuan dalam proses pembelajaran yang ada.

Kata kunci: Management, Content Management System, Assignment
Acerca del uso ritual de las drogas como derecho humano: el caso del peyote en México
Authors: Ruiz Flores López Pamela
Published: May 2019

El presente trabajo repasa la legislación nacional e internacional correspondiente al uso ritual de las drogas en México, misma que, defendiendo los derechos humanos de los pueblos indígenas en el país, cuenta con una protección constitucional y de tratados internacionales para hacer uso pleno de este ritual. Tras un recuento de esta legislación, se analizan los retos a perseguir en la búsqueda de una protección total, y no sólo legislativa. El presente trabajo toma como ejemplo los retos que encuentra el uso ritual del peyote en México, buscando esclarecer la situación actual del empleo ritual de las drogas en el país, así como la agenda pendiente.
The Role of Language and its Analysis in James Joyce`s Dubliners within the Light of Cultural Materialism
Authors: Gaeini Mojgan , Soqandi Mahnaz , Basirizadeh Fatemeh Sadat
Published: May 2019

Language, Social identity and Religion are three major concerns of cultural studies. Language in literary texts plays a major role in constructing meaning and reflecting the author`s intention. Likewise religion as a cultural politics is a dominant factor in shaping mind as well in affecting the framework of literary text. Religion is one of the emerging issues in the modern era and forms the backbone of most literary works. Religion as a theme is seen to influence the operation of those who believe in it. It forms the functional framework that predetermines ones actions and behavior. Furthermore, social identity decides on the status of the social class and their material life situation.  Social identity relates to how we identify ourselves in relation to others according to what we have in common. All these issues are interrelated since they all cooperate and construct a social and cultural materiality. James Joyce could be placed among the most dominant cultural authors whose concern is the material life, social class, social identity and cultural crisis. As an outstanding author, Joyce is well known for his typical depiction, musical decoration as well as his sticking to proper cultural and social materials and issues such as religious matters. His major short story collection, Dubliners, revolves around the lifestyle of the Irish middle-class in Dublin around the late 1800s and early 1900s. This collection is decorated with violated norms and ritualistic behavior that are part of social constructs. Addressing social, religious and cultural issues, cultural materialists believe that “literature can serve as an agent of change”, since a culture`s hegemony is unstable. Raymond Williams views culture as a “productive process” that is, part of the means of production, and cultural materialism often identifies what he called “residual”, “emergent” and “oppositional” cultural elements. Seemingly, James Joyce`s Dubliners pertains to the notion of language, social identity and religion as cultural practices within the framework of cultural materialism. This study aims to clarify how James Joyce`s Dubliners reflects the notions of language, social identity and religion as cultural practices and how they construct social and cultural products within the framework of cultural materialism to show how James Joyce criticizes Irish culture at the beginning of the Twentieth century.
The Effect of Islamic Education Subject on the Development of Student Social Behavior
Authors: Wardany Diny Kristianty
Published: May 2019

This research departs from the assumption that learning Islamic Education is expected to be able to develop several obstacles in the lives of students both in the community and schools to students who behave well, learning activities and introduce good behavior to students, aiming to make students obedient in worshiping in the form of Islamic social morality. This research was conducted with quantitative methods, where data was taken through observation, interviews and research questionnaires, which were then processed using product moment techniques, the purpose of which was to find out the relationship between Islamic Education and the development of students' social behavior. The results showed that Islamic Education and students 'social behavior mostly showed good categories, and the results of hypothesis testing showed that learning Islamic Education had a strong relationship with the development of students' social behavior.
Adverse effects of venlafaxine therapy and risk factors for their occurrence
Authors: Suwała Justyna , Oleś Marta , Wiela-Hojeńska Anna
Published: May 2019

Pharmacovigilance is an important aspect of depression treatment, considering that 40–90% of patients experience side effects of antidepressant use. This paper discusses the issues of optimising the use of venlafaxine, including its pharmacodynamic and pharmacokinetic properties, indications, adverse effects and risk factors for their occurrence, such as co-morbidities or genetic polymorphisms and interactions with other drugs.