bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparison between Male and Female Athletes in Relative Strength and Power Performances
Authors: Bartolomei Sandro , Grillone Giuseppe , Di Michele Rocco , Cortesi Matteo
Published: February 2021

The aim of this study was to compare male vs. female athletes in strength and power performance relative to body mass (BM) and lean body mass (LBM) and to investigate the relationships between muscle architecture and strength in both genders. Sixteen men (age = 26.4 ± 5.0 years; body mass = 88.9 ± 16.6 kg; height = 177.6 ± 9.3 cm) and fourteen women (age = 25.1 ± 3.2 years; body mass = 58.1 ± 9.1 kg; height = 161.7 ± 4.8 cm) were tested for body composition and muscle thickness (MT) of vastus lateralis muscle (VT), pectoralis major (PEC), and trapezius (TRAP). In addition, participants were tested for lower body power at countermovement jump (CMJP) and upper-body power at bench press throw (BPT). Participants were also assessed for one repetition maximum (1RM) at bench press (1RMBP), deadlift (1RMDE), and squat (1RMSQ). Significantly greater (p < 0.01) MT of the VL, PEC and TRAP muscles and LBM were detected in men compared to women. Significantly greater (p < 0.05) 1RMBP and BPT adjusted for LBM were detected in men than in women. No significant gender differences after adjusting for LBM were detected for 1RMSQ (p = 0.945); 1RMDE (p = 0.472) and CMJP (p = 0.656). Significantly greater (p < 0.05) results in all performance assessments adjusted for MT of the specific muscles, were detected in males compared to females. Superior performances adjusted for MT and LBM in men compared to women, may be related to gender differences in muscle morphology and LBM distribution, respectively.
Shielded Active Gas Forge Welding of an L80 Steel in a Small Scale Shielded Active Gas Forge Welding Machine
Authors: Palanisamy Vinothkumar , Solberg Jan Ketil , Moe Per Thomas
Published: February 2021

The Shielded Active Gas Forge Welding (SAG-FW) method is a solid-state welding technique in which the mating surfaces are heated by induction heating or direct electrical heating before being forged together to form a weld. In this article, an API 5CT L80 grade carbon steel alloy has been welded using the SAG-FW method. A small-scale forge welding machine has been used to join miniature pipes extracted from a large pipe wall. The welding was performed at three different forging temperatures, i.e., 1300 °C, 1150 °C and 950 °C, in some cases followed by one or two post weld heat treatment cycles. In order to qualify the welds, mechanical and corrosion testing was performed on miniature samples extracted from the welded pipes. In addition, the microstructure of the welds was analysed, and electron probe microanalysis was carried out to control that no oxide film had formed along the weld line. Based on the complete set of experimental results, promising parameters for SAG-FW welding of the API 5CT L80 grade steel are suggested. The most promising procedure includes forging at relative high temperature (1150 °C) followed by rapid cooling and a short temper. This procedure was found to give a weld zone microstructure dominated by tempered martensite with promising mechanical and corrosion properties. The investigation confirmed that small scale forge welding testing is a useful tool in the development of welding parameters for full size SAG-FW welding.
Evidence for Ecosystem-Level Trophic Cascade Effects Involving Gulf Menhaden (Brevoortia patronus) Triggered by the Deepwater Horizon Blowout
Authors: Short Jeffrey , Voss Christine , Vozzo Maria , Guillory Vincent , Geiger Harold , Haney James , Peterson Charles
Published: February 2021

Unprecedented recruitment of Gulf menhaden (Brevoortia patronus) followed the 2010 Deepwater Horizon blowout (DWH). The foregone consumption of Gulf menhaden, after their many predator species were killed by oiling, increased competition among menhaden for food, resulting in poor physiological conditions and low lipid content during 2011 and 2012. Menhaden sampled for length and weight measurements, beginning in 2011, exhibited the poorest condition around Barataria Bay, west of the Mississippi River, where recruitment of the 2010 year class was highest. Trophodynamic comparisons indicate that ~20% of net primary production flowed through Gulf menhaden prior to the DWH, increasing to ~38% in 2011 and ~27% in 2012, confirming the dominant role of Gulf menhaden in their food web. Hyperabundant Gulf menhaden likely suppressed populations of their zooplankton prey, suggesting a trophic cascade triggered by increased menhaden recruitment. Additionally, low-lipid menhaden likely became “junk food” for predators, further propagating adverse effects. We posit that food web analyses based on inappropriate spatial scales for dominant species, or solely on biomass, provide insufficient indication of the ecosystem consequences of oiling injury. Including such cascading and associated indirect effects in damage assessment models will enhance the ability to anticipate and estimate ecosystem damage from, and provide recovery guidance for, major oil spills.
Dynamic Model Identification of Ships and Wave Energy Converters Based on Semi-Conjugate Linear Regression and Noisy Input Gaussian Process
Authors: Liu Yanjun , Xue Yifan , Huang Shuting , Xue Gang , Jing Qianfeng
Published: February 2021

Reducing the carbon emissions of ships and increasing the utilization of marine renewable energy are the important ways to achieve the goal of carbon neutrality in ocean engineering. Establishing an accurate mathematical model is the foundation of simulating the motion of marine vehicles and structures, and it is the basis of operation energy efficiency optimization and prediction of power generation. System identification from observed input–output data is a practical and powerful method. However, for modeling objects with different characteristics and known information, a single modeling framework can hardly meet the requirements of model establishment. Moreover, there are some challenges in system identification, such as parameter drift and overfitting. In this work, three robust methods are proposed for generating ocean hydrodynamic models based on Bayesian regression. Two Bayesian techniques, semi-conjugate linear regression and noisy input Gaussian process regression are used for parametric and nonparametric gray-box modeling and black-box modeling. The experimental free-running tests of the KRISO very large crude oil carrier (KVLCC2) ship model and a multi-freedom wave energy converter (WEC) are used to validate the proposed Bayesian models. The results demonstrate that the proposed schemes for system identification of the ship and WEC have good generalization ability and robustness. Finally, the developed modeling methods are evaluated considering the aspects required conditions, operating characteristics, and prediction accuracy.
Proximate and Underlying Deforestation Causes in a Tropical Basin through Specialized Consultation and Spatial Logistic Regression Modeling
Authors: Plata-Rocha Wenseslao , Monjardin-Armenta Sergio Alberto , Pacheco-Angulo Carlos Eduardo , Rangel-Peraza Jesus Gabriel , Franco-Ochoa Cuauhtemoc , Mora-Felix Zuriel Dathan
Published: February 2021

The present study focuses on identifying and describing the possible proximate and underlying causes of deforestation and its factors using the combination of two techniques: (1) specialized consultation and (2) spatial logistic regression modeling. These techniques were implemented to characterize the deforestation process qualitatively and quantitatively, and then to graphically represent the deforestation process from a temporal and spatial point of view. The study area is the North Pacific Basin, Mexico, from 2002 to 2014. The map difference technique was used to obtain deforestation using the land-use and vegetation maps. A survey was carried out to identify the possible proximate and underlying causes of deforestation, with the aid of 44 specialized government officials, researchers, and people who live in the surrounding deforested areas. The results indicated total deforestation of 3938.77 km2 in the study area. The most important proximate deforestation causes were agricultural expansion (53.42%), infrastructure extension (20.21%), and wood extraction (16.17%), and the most important underlying causes were demographic factors (34.85%), economics factors (29.26%), and policy and institutional factors (22.59%). Based on the spatial logistic regression model, the factors with the highest statistical significance were forestry productivity, the slope, the altitude, the distance from population centers with fewer than 2500 inhabitants, the distance from farming areas, and the distance from natural protected areas.
The Need for Head Space: Brachycephaly and Cerebrospinal Fluid Disorders
Authors: Rusbridge Clare , Knowler Penny
Published: February 2021

Brachycephalic dogs remain popular, despite the knowledge that this head conformation is associated with health problems, including airway compromise, ocular disorders, neurological disease, and other co-morbidities. There is increasing evidence that brachycephaly disrupts cerebrospinal fluid movement and absorption, predisposing ventriculomegaly, hydrocephalus, quadrigeminal cistern expansion, Chiari-like malformation, and syringomyelia. In this review, we focus on cerebrospinal fluid physiology and how this is impacted by brachycephaly, airorhynchy, and associated craniosynostosis.
Influence of Cr, Mn, Co and Ni Addition on Crystallization Behavior of Al13Fe4 Phase in Al-5Fe Alloys Based on ThermoDynamic Calculations
Authors: Pang Na , Shi Zhiming , Wang Cunquan , Li Ninyu , Lin Yaming
Published: February 2021

Alloying is an effective method to refine coarse grains of an Al13Fe4 phase and strengthen Al-Fe alloys. However, the grain refinement mechanism remains unclear in terms of the thermodynamics. Herein, the influence of M-element, i.e., Cr, Mn, Co and Ni, addition on the activity of Al and Fe atoms, Gibbs free energy of the Al13Fe4 nucleus in Al-Fe melt and the formation enthalpy of an Al13Fe4 phase in Al-Fe alloys is systematically investigated using the extended Miedema model, Wilson equation, and first-principle calculations, respectively. The results reveal that the addition of different M elements increases the activity of Fe atoms and reduces the Gibbs free energy of the Al13Fe4 nucleus in Al-Fe melt, where the incorporation of Ni renders the most obvious effect, followed by Mn, Co, and Cr. Additionally, the formation enthalpy decreases in the following order: Al78(Fe23Cr) > Al78(Fe23Mn) > Al13Fe4 > Al78(Fe23Ni) > Al78(Fe23Co), where the formation enthalpy of Al78(Fe23Ni) is close to Al78(Fe23Co). Moreover, the presence of Ni promotes the nucleation of the Al13Fe4 phase in Al-Fe alloys, which reveals the mechanism of grain refinement from a thermodynamics viewpoint.
Formation of Citrazinic Acid Ions and Their Contribution to Optical and Magnetic Features of Carbon Nanodots: A Combined Experimental and Computational Approach
Authors: Mocci Francesca , Olla Chiara , Cappai Antonio , Corpino Riccardo , Ricci Pier Carlo , Chiriu Daniele , Salis Marcello , Carbonaro Carlo Maria
Published: February 2021

The molecular model is one of the most appealing to explain the peculiar optical properties of Carbon nanodots (CNDs) and was proven to be successful for the bottom up synthesis, where a few molecules were recognized. Among the others, citrazinic acid is relevant for the synthesis of citric acid-based CNDs. Here we report a combined experimental and computational approach to discuss the formation of different protonated and deprotonated species of citrazinic acid and their contribution to vibrational and magnetic spectra. By computing the free energy formation in water solution, we selected the most favoured species and we retrieved their presence in the experimental surface enhanced Raman spectra. As well, the chemical shifts are discussed in terms of tautomers and rotamers of most favoured species. The expected formation of protonated and de-protonated citrazinic acid ions under extreme pH conditions was proven by evaluating specific interactions with H2SO4 and NaOH molecules. The reported results confirm that the presence of citrazinic acid and its ionic forms should be considered in the interpretation of the spectroscopic features of CNDs.
Development and Properties of New Mullite Based Refractory Grog
Authors: Zemánek David , Lang Karel , Tvrdík Lukáš , Všianský Dalibor , Nevřivová Lenka , Štursa Petr , Kovář Pavel , Keršnerová Lucie , Dvořák Karel
Published: February 2021

The presented study is focused on optimization and characterization of a high-alumina refractory aggregate based on natural raw materials—kaolins, claystone, and mullite dust by-product (used to increase the alumina and mullite contents, respectively). In total, four individual formulas with the Al2O3 contents between 45 and 50 wt.% were designed; the samples were subsequently fired, both in a laboratory oven and an industrial tunnel furnace. The effects of repeated firing were examined during industrial pilot tests. Mineral and chemical compositions and microstructures, of both the raw materials and designed aggregates, were thoroughly investigated by the means of X-ray fluorescence spectroscopy, powder X-ray diffraction, and optical and scanning electron microscopies. Porosity, mineral composition, and mullite crystal-size development during the firing process were also studied. Based on the acquired results, the formula with the perspective to be used as a new mullite grog, featuring similar properties as the available commercial products, however, with reduced production expenses, was selected. The quality of grog determines to a large extent the properties of the final product. Hence, optimization of aggregates for specific refractories is of a great importance. The production of engineered aggregates provides the opportunity to utilize industrial by-products.
Prediction of Compressive Strength of Fly Ash Based Concrete Using Individual and Ensemble Algorithm
Authors: Ahmad Ayaz , Farooq Furqan , Niewiadomski Pawel , Ostrowski Krzysztof , Akbar Arslan , Aslam Fahid , Alyousef Rayed
Published: February 2021

Machine learning techniques are widely used algorithms for predicting the mechanical properties of concrete. This study is based on the comparison of algorithms between individuals and ensemble approaches, such as bagging. Optimization for bagging is done by making 20 sub-models to depict the accurate one. Variables like cement content, fine and coarse aggregate, water, binder-to-water ratio, fly-ash, and superplasticizer are used for modeling. Model performance is evaluated by various statistical indicators like mean absolute error (MAE), mean square error (MSE), and root mean square error (RMSE). Individual algorithms show a moderate bias result. However, the ensemble model gives a better result with R2 = 0.911 compared to the decision tree (DT) and gene expression programming (GEP). K-fold cross-validation confirms the model’s accuracy and is done by R2, MAE, MSE, and RMSE. Statistical checks reveal that the decision tree with ensemble provides 25%, 121%, and 49% enhancement for errors like MAE, MSE, and RMSE between the target and outcome response.
Regulating Effect of Cement Accelerator on High Content Solid-Wastes Autoclaved Aerated Concrete (HCS-AAC) Slurry Performance and Subsequent Influence
Authors: Xie Dingkun , Cai Lixiong , Wang Jie
Published: February 2021

Adverse side-effects occurred in slurry foaming and thickening process when carbide slag was substituted for quicklime in HCS-AAC. Cement accelerators were introduced to modify the slurry foaming and coagulating process during pre-curing. Meanwhile, the affiliated effects on the physical-mechanical properties and hydration products were discussed to evaluate the applicability and influence of the cement accelerator. The hydration products were characterized by mineralogical (XRD) and thermal analysis (DSC-TG). The results indicated that substituting carbide slag for quicklime retarded slurry foaming and curing progress; meanwhile, the induced mechanical property declination had a negative effect on the generation of C–S–H (I) and tobermorite. Na2SO4 and Na2O·2.0SiO2 can effectively accelerate the slurry foaming rate, but the promoting effect on slurry thickening was inconspicuous. The compressive strength of HCS-AAC obviously declined with increasing cement coagulant content, which was mainly ascribed to the decrease in bulk density caused by the accelerating effect on the slurry foaming process. Dosing Na2SO4 under 0.4% has little effect on the generation of strength contributing to hydration products while the addition of Na2O·2.0SiO2 can accelerate the generation and crystallization of C–S–H, which contributed to the high activity gelatinous SiO2 generated from the reaction between Na2O·2.0SiO2 and Ca(OH)2.
Properties of a New Insulation Material Glass Bubble in Geopolymer Concrete
Authors: Shahedan Noor Fifinatasha , Abdullah Mohd Mustafa Al Bakri , Mahmed Norsuria , Kusbiantoro Andri , Tammas-Williams Sam , Li Long-Yuan , Aziz Ikmal Hakem , Vizureanu Petrică , Wysłocki Jerzy J. , Błoch Katarzyna , Nabiałek Marcin
Published: February 2021

This paper details analytical research results into a novel geopolymer concrete embedded with glass bubble as its thermal insulating material, fly ash as its precursor material, and a combination of sodium hydroxide (NaOH) and sodium silicate (Na2SiO3) as its alkaline activator to form a geopolymer system. The workability, density, compressive strength (per curing days), and water absorption of the sample loaded at 10% glass bubble (loading level determined to satisfy the minimum strength requirement of a load-bearing structure) were 70 mm, 2165 kg/m3, 52.58 MPa (28 days), 54.92 MPa (60 days), and 65.25 MPa (90 days), and 3.73 %, respectively. The thermal conductivity for geopolymer concrete decreased from 1.47 to 1.19 W/mK, while the thermal diffusivity decreased from 1.88 to 1.02 mm2/s due to increased specific heat from 0.96 to 1.73 MJ/m3K. The improved physicomechanical and thermal (insulating) properties resulting from embedding a glass bubble as an insulating material into geopolymer concrete resulted in a viable composite for use in the construction industry.
Influence of Laboratory Long-Term Aging on Selected Fracture Parameters of Asphalt Mixtures
Authors: Vacková Pavla , Valentin Jan , Belhaj Majda
Published: February 2021

The paper presents the influence of laboratory aging simulation on fracture properties determined on 150 variants of asphalt mixtures. The fracture properties were determined by two different test approaches—semi-circular bending test (SCB test) and three-point bending test on beam specimens (3-PB test). The aging was simulated according to one of the methods defined in EN 12697-52 (storage of test specimens in chamber at temperature of 85 °C for 5 days). The evaluated group of variants covered asphalt mixtures for all road layers. The group was further divided according to used bituminous binder (unmodified vs. modified) and reclaimed asphalt content. The results showed that strength parameters (flexural strength and fracture toughness) increase with aging. It further shows that fracture work provides more complex information about the cracking behavior. For the aging indexes, it was found that for mixtures with modified binders and mixtures which did not contain reclaimed asphalt (RA), the values were higher. The aging indexes for fracture work showed different results for both performed tests.
Aircraft Impact Effects on an Aged NPP
Authors: Lo Frano Rosa
Published: February 2021

The impact of an aircraft is widely known to be one of the worst events that can occur during the operation of a plant (classified for this reason as beyond design). This can become much more catastrophic and lead to the loss of strength of/collapse of the structures when it occurs in the presence of ageing (degradation and alteration) materials. Therefore, since the performance of all plant components may be affected by ageing, there is a need to evaluate the effect that aged components have on system performance and plant safety. This study addresses the numerical simulation of an aged Nuclear Power Plant (NPP) subjected to a military aircraft impact. The effects of impact velocity, direction, and location were investigated together with the more unfavorable conditions to be expected for the plant. The modelling method was also validated based on the results obtained from the experiments of Sugano et al., 1993. Non-linear analyses by means of finite element (FE) MARC code allowed us to simulate the performance of the reinforced concrete containment building and its impact on plant availability and reliability. The results showed that ageing increases a plant’s propensity to suffer damage. The damage at the impact area was confirmed to be dependent on the type of aircraft involved and the target wall thickness. The greater the degradation of the materials, the lower the residual resistance capacity, and the greater the risk of wall perforation.
Predicting Workability of a Low-Cost Powder Metallurgical Ti–5Al–2Fe–3Mo Alloy Using Constitutive Modeling and Processing Map
Authors: Pan Di , Liu Bin , Xu Rongjun , Qiu Jingwen , Liu Chunxuan
Published: February 2021

A low-cost titanium alloy (Ti–5Al–2Fe–3Mo wt.%) was designed and fabricated by blended elemental powder metallurgy (BEPM) process. The high-temperature deformation behavior of the powder metallurgical Ti–5Al–2Fe–3Mo wt.% (PM-TiAlFeMo) alloy was investigated by hot compression tests at temperatures ranging from 700 to 1000 °C and strain rates ranging from 0.001 to 10 s−1. The flow curves were employed to develop the Arrhenius-type constitutive model in consideration of effects of deformation temperature, strain rate, and flow stress. The value of activation energy (Q) was determined as 413.25 kJ/mol. In order to describe the workability and predict the optimum hot processing parameters of the PM-TiAlFeMo alloy, the processing map has been established based on the true stress–true strain curves and power dissipation efficiency map. Moreover, microstructure observations match well with the analyses about deformation mechanisms, revealing that dynamic recovery and dynamic recrystallization are dominant softening mechanisms at relatively high temperatures. However, the kinking and breaking of microstructure prefer to occur at relatively low temperatures.
Wiener–Hosoya Matrix of Connected Graphs
Authors: Ibrahim Hassan , Sharafdini Reza , Réti Tamás , Akwu Abolape
Published: February 2021

Let G be a connected (molecular) graph with the vertex set V(G)={v1,⋯,vn}, and let di and σi denote, respectively, the vertex degree and the transmission of vi, for 1≤i≤n. In this paper, we aim to provide a new matrix description of the celebrated Wiener index. In fact, we introduce the Wiener–Hosoya matrix of G, which is defined as the n×n matrix whose (i,j)-entry is equal to σi2di+σj2dj if vi and vj are adjacent and 0 otherwise. Some properties, including upper and lower bounds for the eigenvalues of the Wiener–Hosoya matrix are obtained and the extremal cases are described. Further, we introduce the energy of this matrix.
Antiviral Potential of Algal Metabolites—A Comprehensive Review
Authors: Pagarete António , Ramos Ana Sofia , Puntervoll Pål , Allen Michael J. , Verdelho Vítor
Published: February 2021

Historically, algae have stimulated significant economic interest particularly as a source of fertilizers, feeds, foods and pharmaceutical precursors. However, there is increasing interest in exploiting algal diversity for their antiviral potential. Here, we present an overview of 50-years of scientific and technological developments in the field of algae antivirals. After bibliometric analysis of 999 scientific references, a survey of 16 clinical trials and analysis of 84 patents, it was possible to identify the dominant algae, molecules and viruses that have been shaping and driving this promising field of research. A description of the most promising discoveries is presented according to molecule class. We observed a diverse range of algae and respective molecules displaying significant antiviral effects against an equally diverse range of viruses. Some natural algae molecules, like carrageenan, cyanovirin or griffithsin, are now considered prime reference molecules for their outstanding antiviral capacity. Crucially, while many algae antiviral applications have already reached successful commercialization, the large spectrum of algae antiviral capacities already identified suggests a strong potential for future expansion of this field.
The Rare Case of Perirenal Abscess in a Child—Possible Mechanisms and Methods of Treatment: A Case Report and Literature Review
Authors: Sosnowska-Sienkiewicz Patrycja , Bućko Ewa , Mańkowski Przemysław
Published: February 2021

Renal and perirenal abscesses are very rare in children. They can be present as an acute emergency condition or insidiously as a chronic disease. The diagnosis is not so obvious, and it is a big challenge, especially when it can simulate a kidney tumor. The treatment can be conservative, preferably with targeted antibiotics, or surgical, consisting primarily of drainage. This publication aims to present a clinical case in which both diagnosis and treatment were a big challenge for the entire treatment team. A 10-year-old male patient was admitted to the hospital because of mild abdominal pain and a temperature of 37.5 °C. The symptoms lasted for a week. In the computed tomography (CT), the lesion’s dimensions were 11.1 × 8.2 × 25 cm, and inflammation, abscess, cyst, and abdominal tumor have been suggested. The decision about surgical treatment was made. An enormous abscess near the right kidney was localized. The patient’s condition stabilized after surgery. Unfortunately, due to persistent purulent reservoirs, a second laparotomy was necessary. During the extensive diagnostic cystourethrography performed, vesicoureteral reflux was visualized. In conclusion, though a perinephric abscess is very rare in children, it should be taken into consideration in patients with non-specific abdominal symptoms. The imaging using ultrasound and CT scan with contrast enhancement is crucial to recognize and properly treat the condition. In terms of a small abscess, the only antimicrobial treatment using antibiotics of a broad spectrum can be considered. However, the drainage of an abscess, either percutaneous or open, should be used. For the large abscess, the open drainage seems to be a primary method of treatment. The importance of cooperation in a multidisciplinary team is crucial, as the diagnosis and treatment of underlying causes are essential.
Neuropsychiatric Consequences of Lipophilic Beta-Blockers
Authors: Cojocariu Sabina Alexandra , Maștaleru Alexandra , Sascău Radu Andy , Stătescu Cristian , Mitu Florin , Leon-Constantin Maria Magdalena
Published: February 2021

Beta-blockers are a class of drugs with important benefits in cardiovascular pathology. In this paper, we aim to highlight their adverse and therapeutic effects in the neuropsychiatric field. With respect to permeability, we would like to mention that most beta-blockers are lipophilic and can cross the blood–brain barrier. Observational studies show the presence of neuropsychiatric side effects when taking beta-blockers, and is the reason for which caution is recommended in their use in patients with depressive syndrome. From a therapeutic point of view, most current evidence is for the use of beta-blockers in migraine attacks, essential tremor, and akathisia. Beta-blockers appear to be effective in the treatment of aggressive behavior, beneficial in the prevention of posttraumatic stress syndrome and may play a role in the adjuvant treatment of obsessive–compulsive disorder, which is refractory to standard therapy. In conclusion, the relationship between beta-blockers and the central nervous system appears as a two-sided coin. Summarizing the neuropsychiatric side effects of beta-blockers, we suggest that clinicians pay special attention to the pharmacological properties of different beta-blockers.
The Role of Exercise to Reduce the Impact of Diabetes in the Seminal Quality: A Systematic Review
Authors: Lavín-Pérez Ana Myriam , Collado-Mateo Daniel , Villafaina Santos , Calle-Guisado Violeta
Published: February 2021

Background and Objectives: One of the most relevant consequences of diabetes mellitus is the temporal or complete infertility which can happen in young individuals. Therefore, the current systematic review aimed to investigate the effects of exercise to reduce the impact of Type 2 Diabetes Mellitus (T2DM) in seminal quality and related parameters. Materials and Methods: A systematic search was conducted in Pubmed and Web of Science databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (1) the study included at least one experimental and one comparison group, (2) the sample of the study was comprised of humans or animals with diabetes mellitus, (3) an intervention based on physical exercise was conducted, and (4) the study reported variables related to the seminal quality. Results: A total of 115 articles were identified. However, only six accomplished the inclusion and exclusion criteria. This systematic review includes a sample size of 260 participants (180 rats and 80 humans). Intervention ranged from 6 to 14 weeks, with 3–6 days per week. All interventions performed endurance training (50–70% VO2max or maximum heart rate). Physical exercise increased sperm count, motility, and morphology, as well as improved testosterone, Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH) levels. Moreover, physical exercise intervention reduced the percentages of sperms with negative Tubular Differentiation Index (TDI) and Spermiogenesis Index (SPI), DNA fragmentation, and also ameliorated the diabetes-induced apoptosis and improved sperm apoptosis index. Conclusions: Physical exercise could ameliorate diabetic pathological effects on sperm quality and related parameters that cause infertility or subfertility conditions. However, further homogeneous studies are needed to confirm these findings.
Mutual Influence of Psoriasis and Sport
Authors: Custurone Paolo , Macca Laura , Bertino Lucrezia , Di Mauro Debora , Trimarchi Fabio , Vaccaro Mario , Borgia Francesco
Published: February 2021

The link between psoriasis and sport is a controversial issue. The topic has been poorly investigated, and nowadays there are many unsolved questions, dealing with the role of psoriasis in influencing the sporting habits of patients and, vice versa, the impact of sport activity on course, severity and extent of the disease, with particular regard to the indirect benefits on cardiovascular risk and metabolic syndrome. Moreover, the role of physical activity on patients’ quality of life and the potential limitations on physical activity due to joint involvement have not been well elucidated until now. In this narrative review we will try to provide answers to these queries.
Mathematical Modeling of the Effect of Pulsed Electric Field on the Specific Permselectivity of Ion-Exchange Membranes
Authors: Gorobchenko Andrey , Mareev Semyon , Nikonenko Victor
Published: February 2021

The application of pulsed electric field (PEF) in electrodialysis has been proven to be efficient for a number of effects: increasing mass transfer rate, mitigation of scaling and fouling, reducing water splitting. Recently, the improvement of the membrane permselectivity for specific counterions was discovered experimentally by the group of Laurent Bazinet (N. Lemay et al. J. Memb. Sci. 604, 117878 (2020)). To better understanding the effect of PEF in electrodialysis, simulations were performed using a non-stationary mathematical model based on the Nernst–Planck and Poisson equations. For the first time, it was not only the condition used when the current density is specified but also the condition when the voltage is set. A membrane and two adjacent diffusion layers are considered. It is shown that when applying the regime used by Lemay et al. (the same current density in conventional continuous current (CC) mode and during the pulses in PEF mode), there is a significant gain in specific permselectivity. It is explained by a reduction in the membrane concentration polarization in PEF mode. In the CC mode of electrodialysis, increasing current density leads to a loss in specific permselectivity: concentration profiles in the diffusion layers and membrane are formed in such a way that ion diffusion reduces the migration flux of the preferentially transferred ion and increases that of the poorly transferred ion. In PEF mode, the concentration profiles are partially restored during the pauses when the current is zero. However, if a different condition is used than the condition applied by Lemay et al., that is, when the same average current density is applied in both the PEF and CC modes, there is no gain in specific permeability. It is shown that within the framework of the applied mathematical model, the specific selectivity depends only on the average current density and does not depend on the mode of its application (CC or PEF mode).
Porous Hydrophobic–Hydrophilic Composite Hollow Fiber and Flat Membranes Prepared by Plasma Polymerization for Direct Contact Membrane Distillation
Authors: Sharma Ashok K. , Juelfs Adam , Colling Connor , Sharma Saket , Conover Stephen P. , Puranik Aishwarya A. , Chau John , Rodrigues Lydia , Sirkar Kamalesh K.
Published: February 2021

High water vapor flux at low brine temperatures without surface fouling is needed in membrane distillation-based desalination. Brine crossflow over surface-modified hydrophobic hollow fiber membranes (HFMs) yielded fouling-free operation with supersaturated solutions of scaling salts and their precipitates. Surface modification involved an ultrathin porous polyfluorosiloxane or polysiloxane coating deposited on the outside of porous polypropylene (PP) HFMs by plasma polymerization. The outside of hydrophilic MicroPES HFMs of polyethersulfone was also coated by an ultrathin coating of porous plasma-polymerized polyfluorosiloxane or polysiloxane rendering the surface hydrophobic. Direct contact membrane distillation-based desalination performances of these HFMs were determined and compared with porous PP-based HFMs. Salt concentrations of 1, 10, and 20 wt% were used. Leak rates were determined at low pressures. Surface and cross-sections of two kinds of coated HFMs were investigated by scanning electron microscopy. The HFMs based on water-wetted MicroPES substrate offered a very thin gas gap in the hydrophobic surface coating yielding a high flux of 26.4–27.6 kg/m2-h with 1 wt% feed brine at 70 °C. The fluxes of HFMs on porous PP substrates having a long vapor diffusion path were significantly lower. Coated HFM performances have been compared with flat hydrophilic membranes of polyvinylidene fluoride having a similar plasma-polymerized hydrophobic polyfluorosiloxane coating.
Electrosynthesis of Electrochromic Polymer Membranes Based on 3,6-Di(2-thienyl)carbazole and Thiophene Derivatives
Authors: Kuo Chung-Wen , Chang Jui-Cheng , Chang Jeng-Kuei , Huang Sheng-Wei , Lee Pei-Ying , Wu Tzi-Yi
Published: February 2021

Five carbazole-containing polymeric membranes (PDTC, P(DTC-co-BTP), P(DTC-co-BTP2), P(DTC-co-TF), and P(DTC-co-TF2)) were electrodeposited on transparent conductive electrodes. P(DTC-co-BTP2) shows a high ΔT (68.4%) at 855 nm. The multichromic properties of P(DTC-co-TF2) membrane range between dark yellow, yellowish-green, gunmetal gray, and dark gray in various reduced and oxidized states. Polymer-based organic electrochromic devices are assembled using 2,2′-bithiophene- and 2-(2-thienyl)furan-based copolymers as anodic membranes, and poly(3,4-ethylenedioxythiophene)-poly(styrene sulfonic acid) (PEDOT-PSS) as the cathodic membrane. P(DTC-co-TF)/PEDOT-PSS electrochromic device (ECD) displays a high transmittance change (ΔT%) (43.4%) at 627 nm as well as a rapid switching time (less than 0.6 s) from a colored to a bleached state. Moreover, P(DTC-co-TF2)/PEDOT-PSS ECD shows satisfactory optical memory (the transmittance change is less than 2.9% in the colored state) and high coloration efficiency (512.6 cm2 C−1) at 627 nm.
Selected Aspects of Cohesive Zone Modeling in Fracture Mechanics
Authors: Wciślik Wiktor , Pała Tadeusz
Published: February 2021

This review paper discusses the basic problems related to the use of cohesive models to simulate the initiation and development of failure in various types of engineering issues. The most commonly used cohesive zone models (CZMs) are described. Recent achievements in the field of cohesive modeling are characterized, with particular emphasis on the problem of mixed mode loading, the influence of the strain rate, the stress state triaxiality, and fatigue. A separate chapter of the work is devoted to the identification of cohesive parameters. Examples of the use of CZMs for the analysis of the fracture and failure process in various applications, both on the macro and microscopic scale, are given. The directions of CZMs development were indicated as well as the issues that are currently under particularly intensive development.
Influence of Aluminum on Fatigue Strength of Solution-Strengthened Nodular Cast Iron
Authors: Gebhardt Christian , Nellessen Johannes , Bührig-Polaczek Andreas , Broeckmann Christoph
Published: February 2021

The fatigue strength of high silicon-alloyed nodular cast iron is influenced by casting defects and graphite precipitates. The literature as well as the findings of this work show that these microstructural constituents can be tailored by controlling silicon microsegregation. In addition, segregations also affect the ferritic matrix microstructure locally. In the present work, silicon segregations in high silicon-alloyed ductile iron are specifically manipulated by small additions of aluminum. It was demonstrated how the aluminum content affects a wide range of microstructural constituents across a variety of length scales. Specimens from alloys with small additions of aluminum were fabricated and tested by rotating bending. Results show that the fatigue strength can be increased compared to a reference alloy with no aluminum. Microstructure analysis as well as fractography were performed concluding that microstructural changes could be attributed to the increased aluminum content, which allows the fatigue properties to be tailored deliberately. However, according to the results of this study, the negative effect of aluminum on castability and graphite morphology limits the maximum content to approximately 0.2 wt.%.
Targeted Metabolomic Assessment of the Sub-Lethal Toxicity of Halogenated Acetic Acids (HAAs) to Daphnia magna
Authors: Labine Lisa M. , Simpson Myrna J.
Published: February 2021

Halogenated acetic acids (HAAs) are amongst the most frequently detected disinfection by-products in aquatic environments. Despite this, little is known about their toxicity, especially at the molecular level. The model organism Daphnia magna, which is an indicator species for freshwater ecosystems, was exposed to sub-lethal concentrations of dichloroacetic acid (DCAA), trichloroacetic acid (TCAA) and dibromoacetic acid (DBAA) for 48 h. Polar metabolites extracted from Daphnia were analyzed using liquid chromatography hyphened to a triple quadrupole mass spectrometer (LC-MS/MS). Multivariate analyses identified shifts in the metabolic profile with exposure and pathway analysis was used to identify which metabolites and associated pathways were disrupted. Exposure to all three HAAs led to significant downregulation in the nucleosides: adenosine, guanosine and inosine. Pathway analyses identified perturbations in the citric acid cycle and the purine metabolism pathways. Interestingly, chlorinated and brominated acetic acids demonstrated similar modes of action after sub-lethal acute exposure, suggesting that HAAs cause a contaminant class-based response which is independent of the type or number of halogens. As such, the identified metabolites that responded to acute HAA exposure may serve as suitable bioindicators for freshwater monitoring programs.
Elevated Trehalose Levels in C. elegans daf-2 Mutants Increase Stress Resistance, Not Lifespan
Authors: Rasulova Madina , Zečić Aleksandra , Monje Moreno Jose Manuel , Vandemeulebroucke Lieselot , Dhondt Ineke , Braeckman Bart P.
Published: February 2021

The C. elegans insulin/IGF-1 (insulin-like growth factor 1) signaling mutant daf-2 recapitulates the dauer metabolic signature—a shift towards lipid and carbohydrate accumulation—which may be linked to its longevity and stress resistance phenotypes. Trehalose, a disaccharide of glucose, is highly upregulated in daf‑2 mutants and it has been linked to proteome stabilization and protection against heat, cold, desiccation, and hypoxia. Earlier studies suggested that elevated trehalose levels can explain up to 43% of the lifespan extension observed in daf-2 mutants. Here we demonstrate that trehalose accumulation is responsible for increased osmotolerance, and to some degree thermotolerance, rather than longevity in daf-2 mutants. This indicates that particular stress resistance phenotypes can be uncoupled from longevity.
Hemp-Based Microfluidics
Authors: Temirel Mikail , Dabbagh Sajjad Rahmani , Tasoglu Savas
Published: February 2021

Hemp is a sustainable, recyclable, and high-yield annual crop that can be used to produce textiles, plastics, composites, concrete, fibers, biofuels, bionutrients, and paper. The integration of microfluidic paper-based analytical devices (µPADs) with hemp paper can improve the environmental friendliness and high-throughputness of µPADs. However, there is a lack of sufficient scientific studies exploring the functionality, pros, and cons of hemp as a substrate for µPADs. Herein, we used a desktop pen plotter and commercial markers to pattern hydrophobic barriers on hemp paper, in a single step, in order to characterize the ability of markers to form water-resistant patterns on hemp. In addition, since a higher resolution results in densely packed, cost-effective devices with a minimized need for costly reagents, we examined the smallest and thinnest water-resistant patterns plottable on hemp-based papers. Furthermore, the wicking speed and distance of fluids with different viscosities on Whatman No. 1 and hemp papers were compared. Additionally, the wettability of hemp and Whatman grade 1 paper was compared by measuring their contact angles. Besides, the effects of various channel sizes, as well as the number of branches, on the wicking distance of the channeled hemp paper was studied. The governing equations for the wicking distance on channels with laser-cut and hydrophobic side boundaries are presented and were evaluated with our experimental data, elucidating the applicability of the modified Washburn equation for modeling the wicking distance of fluids on hemp paper-based microfluidic devices. Finally, we validated hemp paper as a substrate for the detection and analysis of the potassium concentration in artificial urine.
Recent Advances in Ammonia Gas Sensors Based on Carbon Nanomaterials
Authors: Bannov Alexander G. , Popov Maxim V. , Brester Andrei E. , Kurmashov Pavel B.
Published: February 2021

This review paper is devoted to an extended analysis of ammonia gas sensors based on carbon nanomaterials. It provides a detailed comparison of various types of active materials used for the detection of ammonia, e.g., carbon nanotubes, carbon nanofibers, graphene, graphene oxide, and related materials. Different parameters that can affect the performance of chemiresistive gas sensors are discussed. The paper also gives a comparison of the sensing characteristics (response, response time, recovery time, operating temperature) of gas sensors based on carbon nanomaterials. The results of our tests on ammonia gas sensors using various techniques are analyzed. The problems related to the recovery of sensors using various approaches are also considered. Finally, the impact of relative humidity on the sensing behavior of carbon nanomaterials of various different natures was estimated.
Unveiling the Bovine Epimural Microbiota Composition and Putative Function
Authors: Pacífico Cátia , Petri Renée Maxine , Ricci Sara , Mickdam Elsayed , Wetzels Stefanie Urimare , Neubauer Viktoria , Zebeli Qendrim
Published: February 2021

Numerous studies have used the 16S rRNA gene target in an attempt to characterize the structure and composition of the epimural microbiota in cattle. However, comparisons between studies are challenging, as the results show large variations associated with experimental protocols and bioinformatics methodologies. Here, we present a meta-analysis of the rumen epimural microbiota from 11 publicly available amplicon studies to assess key technical and biological sources of variation between experiments. Using the QIIME2 pipeline, 332 rumen epithelial microbiota samples were analyzed to investigate community structure, composition, and functional potential. Despite having a significant impact on microbial abundance, country of origin, farm, hypervariable region, primer set, animal variability, and biopsy location did not obscure the identification of a core microbiota. The bacterial genera Campylobacter, Christensenellaceae R-7 group, Defluviitaleaceae UCG-011, Lachnospiraceae UCG-010, Ruminococcaceae NK4A214 group, Ruminococcaceae UCG-010, Ruminococcaceae UCG-014, Succiniclasticum, Desulfobulbus, and Comamonas spp. were found in nearly all epithelium samples (>90%). Predictive analysis (PICRUSt) was used to assess the potential functions of the epithelial microbiota. Regularized canonical correlation analysis identified several pathways associated with the biosynthesis of precursor metabolites in Campylobacter, Comamonas, Desulfobulbus, and Ruminococcaceae NK4A214, highlighting key metabolic functions of these microbes within the epithelium.
Gut–Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions
Authors: De Pessemier Britta , Grine Lynda , Debaere Melanie , Maes Aglaya , Paetzold Bernhard , Callewaert Chris
Published: February 2021

The microbiome plays an important role in a wide variety of skin disorders. Not only is the skin microbiome altered, but also surprisingly many skin diseases are accompanied by an altered gut microbiome. The microbiome is a key regulator for the immune system, as it aims to maintain homeostasis by communicating with tissues and organs in a bidirectional manner. Hence, dysbiosis in the skin and/or gut microbiome is associated with an altered immune response, promoting the development of skin diseases, such as atopic dermatitis, psoriasis, acne vulgaris, dandruff, and even skin cancer. Here, we focus on the associations between the microbiome, diet, metabolites, and immune responses in skin pathologies. This review describes an exhaustive list of common skin conditions with associated dysbiosis in the skin microbiome as well as the current body of evidence on gut microbiome dysbiosis, dietary links, and their interplay with skin conditions. An enhanced understanding of the local skin and gut microbiome including the underlying mechanisms is necessary to shed light on the microbial involvement in human skin diseases and to develop new therapeutic approaches.