bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of cardiac rehabilitation on elderly patients with Chronic heart failure: A meta-analysis and systematic review
Authors: Chen Zhuang , Li Ming , Yin Chenghua , Fang Youbo , Zhu Ye , Feng Jing
Published: August 2022

Aims

The purpose of this study was to investigate the effects of cardiac rehabilitation (CR) on elderly patients with Chronic heart failure (CHF) by literature search and meta-analysis.

Methods

We conducted an electronic search on PubMed, Cochrane Library, Embase, CNKI, Wanfang, and VIP database platforms. The search period was from the establishment of the database to November 2021 for randomized controlled studies (RCTs) related to the effects of CR on elderly patients with CHF. The RevMan 5.4 was used for meta-analysis.

Results

This study included 16 articles involving a total of 1782 patients, including 892 in the CR group and 890 in the control group. Meta-analysis showed that compared with conventional interventions, CR increased left ventricular ejection fraction in elderly patients with CHF [mean difference (MD):5.73,95% confidence interval (CI):2.05 to 9.40,Z = 3.05,P = 0.002], and decreased left ventricular end-diastolic diameter in elderly patients with CHF (MD:-4.82,95%CI:-7.49 to 15,Z = 3.54,P = 0.0004), increased the 6-minute walk test distance (MD:62.66,95% CI:44.40 to 80.92,Z = 6.72,P<0.00001), decreased the rehospitalization rate (OR:0.32,95%) CI: 0.21 0.49, Z = 5.33, P < 0.000001).

Conclusions

CR can improve cardiac function, prognosis and reduce rehospitalization rate of elderly patients with CHF.
‘We just don’t have this in us…’: Understanding factors behind low levels of physical activity in South Asian immigrants in Metro-Vancouver, Canada
Authors: Mahmood Bushra , Cox Susan , Ashe Maureen C. , Nettlefold Lindsay , Deo Neha , Puyat Joseph H. , Tang Tricia S.
Published: August 2022

Background

South Asian immigrants in western countries are at a high risk for metabolic syndrome and associated chronic disease. While a physically active lifestyle is crucial in decreasing this risk, physical activity (PA) levels among this group remain low. The objectives of this study were to explore social and cultural factors that influence PA behavior, investigate how immigration process intersects with PA behaviors to influence PA levels and to engage community in a discussion about what can be done to increase PA in the South Asian community.

Methods

For this qualitative study, we conducted four Focus Group Discussions (FGDs) among a subset of participants who were part of a larger study. FGD data was coded and analysed using directed content analysis to identify key categories.

Results

Participants expressed a range of opinions, attitudes and beliefs about PA. Most believed they were sufficiently active. Women talked about restrictive social and cultural norms that discouraged uptake of exercise. Post-immigration levels of PA were low due to change in type of work and added responsibilities.

Conclusion

Health promoters need to consider social, cultural, and structural contexts when exploring possible behavior change interventions for South Asian immigrants.
Effects of breathing reeducation on cervical and pulmonary outcomes in patients with non specific chronic neck pain: A double blind randomized controlled trial
Authors: Anwar Sahreen , Arsalan Asadullah , Zafar Hamayun , Ahmad Ashfaq , Hanif Asif
Published: August 2022

Objective

The purpose of this randomized controlled trial was to study effects of breathing reeducation in the treatment of patients with non specific chronic neck pain.

Methods

A total of sixty eight eligible patients with chronic neck pain were randomly allocated to breathing reeducation (BR) group (n = 34) and routine physical therapy (RPT) group (n = 34). Clinical outcomes were neck pain measured through visual analogue score, cervical active range of motion through CROM device, strength of neck muscles through hand held dynamometer and endurance of neck muscles measured through craniocervical flexion test. The neck disability was measured through neck disability index (NDI) and pulmonary outcomes such as forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and FEV1/FVC ratio were measured through Spirolab 4. The outcomes were assessed at baseline and at 4 and at 8 weeks from baseline.

Results

There were significant improvements in the BR group compared with the RPT group (P = 0.002) for cervical flexion, extension (P = 0.029), endurance (P = 0.042), strength of neck flexors (P <0.001), neck extensors (P = 0.034). Likewise there was a significant change in NDI (P = 0.011), FEV1 (P = 0.045), FVC (P <0.001), and FEV1/FVC ratio (P <0.001) in the BR group compared with the RPT group. The cervical side flexion and rotation showed no significant difference in breathing reeducation group with p > 0.05.

Conclusion

Breathing reeducation combined with routine physical therapy is an effective treatment in patients with non specific chronic neck pain.

Trial registration

IRCT 20200226046623N1, https://www.irct.ir/trial/46240.
SARS-CoV-2 infections in infants in Haiti 2020–2021; evidence from a seroepidemiological cohort
Authors: Louis Rigan , Pu Ruiyu , Logan Tracey D. , Trimmer-Smith Luke , Chamblain Richard , Gallagher Adriana , De Rochars Valery Madsen Beau , Nelson Eric , Cummings Derek A. T. , Long Maureen T. , Morris J. Glenn
Published: August 2022

Few data are available on frequency of SARS-CoV-2 infection among very young children in low- to middle-income countries (LMIC), with the studies that are available biased towards higher income countries with low reported infection and seroconversion rates. Between February 2019 and March 2021, 388 dried blood spot (DBS) samples were obtained from 257 children less than 30 months of age as part of a prospective observational cohort study of pregnant women and their infants in Haiti; longitudinal samples were available for 107 children. In a subsequent retrospective analysis, DBS samples were tested by ELISA for antibody targeting the receptor binding domain of the SARS-CoV-2 S1 protein. Over the course of the study, 16·7% of the infants became seropositive. All seropositive samples were collected after March 19, 2020 (the date of the first reported COVID-19 case in Haiti) with the highest hazards measured in August 2020. Sampling date was the only covariate associated with the hazard of seroconversion. Our data provide an estimate of SARS-CoV-2 infection rates among very young children without prior SARS-CoV-2 exposure during the initial pandemic waves in Haiti, and demonstrate that these children mount a detectable serological response which is independent of patient age.
Aerobic exercise regulates FGF21 and NLRP3 inflammasome-mediated pyroptosis and inhibits atherosclerosis in mice
Authors: Li Xiao-Hong , Liu Liang-Zhong , Chen Lin , Pan Qi-Ni , Ouyang Zi-Yao , Fan De-Jing , Pan Xiao , Lu Su-Yu , Luo Qiu-Hu , Tao Pin-Yue , Huang Hui-Qiao
Published: August 2022

Fibroblast growth factor 21 (FGF21), a known risk factor for atherosclerosis, is readily regulated by exercise, and it can inhibit NOD-like receptor protein 3 (NLRP3)-mediated pyroptosis. However, it is not clear whether aerobic exercise inhibits atherosclerosis via these pathways. Eight-week-old apolipoprotein E-deficient (ApoE-/-) mice on a high-fat diet were randomly divided into 1-h post-exercise (EX-1h), 24-h post-exercise (EX-24h), and sedentary (SED) groups. C57BL/6J wild-type mice fed normal chow served as controls (WT group). Mice in the EX-1h and EX-24h groups were subjected to treadmill exercise training for 12 weeks. Aerobic exercise reduced body weight; blood glucose, lipid, and inflammation levels; and aortic plaque area proportion. Aerobic exercise increased the sensitivity of FGF21 by upregulating the expression of the downstream receptor adiponectin (ApN); the serum FGF21 level after exercise increased initially, and then decreased. Aerobic exercise downregulated the expression of NLRP3 inflammasome-mediated pyroptosis-related markers in the aorta, and FGF21 may participate in the above process. Meanwhile, the liver may be the tissue source of serum FGF21 during aerobic exercise. In conclusion, aerobic exercise may inhibit atherogenesis by regulating FGF21 and NLRP3 inflammasome-mediated pyroptosis. Our study provides new information on the atherosclerosis-preventing mechanism of aerobic exercise.
Relationships of sphenoid sinus pneumatization with internal carotid artery characteristics
Authors: Kang Yun Jin , Cho Jin-Hee , Kim Do Hyun , Kim Sung Won
Published: August 2022

Objective

We explored the clinical significances of the relationships among sphenoid sinus aeration, intersphenoid sinus septum (ISS), and internal carotid artery (ICA).

Methods

We retrospectively reviewed the preoperative paranasal sinus computed tomography scans and the medical charts of 490 patients who were treated by the endoscopic endonasal transsphenoidal approach. We analyzed sphenoid sinus pneumatization, number of ISS, and positional relationships between the ICA and ISS (including ICA prominence and the thickness of surrounding bone).

Results

ISS were often present in the ICAs of patients with presellar pneumatization (36.2%; p = 0.042). Sphenoid sinus pneumatization status significantly differed according to number of ISS (p < 0.001), ICA prominence (p < 0.001), ISS insertion into the ICA (p = 0.042), and distance from ISS to ICA (p = 0.004). When sphenoid sinus aeration was poor, the ICA was not prominent, and the ISS were attached to or lay close to the paraclival ICA.

Conclusions

Patients with presellar pneumatization exhibited less prominent ICAs, and more ISS attached to or near the paraclival ICA, than did other patients. Therefore, particular caution is required when using the endoscopic endonasal transsphenoidal approach to treat patients with poor sphenoid sinus aeration.
Network analysis based on big data in social media of Korean adolescents’ diet behaviors
Authors: Song JongHwi , Yoo SooYeun , Yang JunRyul , Yun SangKyun , Shin YunHee
Published: August 2022

Adolescents are increasingly interested in weight control; hence, proper health education is important for helping them control their weight properly. This study was designed to pick out social media words that express adolescents’ diet behaviors, and identify the associations and types between such words and the behaviors. It used text-mining techniques and semantic network analysis for related big data collected from the Internet on adolescents’ diet behaviors. Text mining was used to extract meaningful information from unstructured text data, whereas semantic network analysis was used to understand the relationships between keywords. The top five keywords were “obesity,” “health,” “exercise,” “eat,” and “increase” in online news, and “exercise,” “eat,” “weight loss,” “obesity,” and “health” in blogs. The betweenness centrality of “appearance” was particularly higher than that of other centralities in online news. As a result of the CONCOR analysis, eight clusters each were identified in online news and blogs. This study’s results will serve as a basis for weight management-related intervention strategies, reflecting the perspectives of adolescents. It also has significance as basic data to provide correct information, and establish desirable weight control in the future.
Exploring healthcare providers’ perceptions regarding the prevention and treatment of chronic pain in breast cancer survivors: A qualitative analysis among different disciplines
Authors: Slaghmuylder Yaël , Pype Peter , Van Hecke Ann , Lauwerier Emelien
Published: August 2022

Background

The prevention and treatment of chronic pain problems in breast cancer follow-up care require an adequate response from healthcare providers. Generally, this involves the uptake of evidence-based principles regarding pain management in everyday practice. However, despite the extensive literature on effective pain interventions, systematic and coordinated follow-up care is lacking for breast cancer survivors with pain problems in Flanders, Belgium.

Objective

This study aimed to gather insight into healthcare providers’ perceptions of pain prevention and treatment in breast cancer follow-up care, particularly with attention to the multilevel influences on pain follow-up.

Methods

We conducted four online focus groups with twenty-two healthcare providers from different disciplines such as oncologists, pharmacists, nurses, physiotherapists, and psychologists. Data analysis was guided by the Qualitative Analysis Guide of Leuven. This guide is inspired by the constant comparison method, based on Grounded Theory.

Results

The identified influencing factors were thematically grouped into four levels: at the level of the individual healthcare provider, in interaction with the patient, in interaction with colleagues, and at the context level. At each level, we distinguished factors related to healthcare providers’ perceptions such as awareness, knowledge, attitudes, beliefs, experiences, and intentions. For example, because of a lack of knowledge and certain beliefs among healthcare providers, referral to other disciplines often does not happen in the context of pain.

Conclusion

This study points out the need to explore the prevention and treatment of chronic pain after breast cancer from a multidimensional point of view. This involves not only the characteristics of individual healthcare providers but is also inherently interactional and system-like in nature. This analysis provides opportunities for the development of interventions that target the influencing factors of prevention and treatment of chronic pain in breast cancer survivors.
Age differences in functioning and contextual factors in community-dwelling stroke survivors: A national cross-sectional survey
Authors: Olafsdottir Steinunn A. , Hjaltadottir Ingibjörg , Galvin Rose , Hafsteinsdottir Thora B. , Jonsdottir Helga , Arnadottir Solveig A.
Published: August 2022

Background

Our study aimed to map functioning and contextual factors among community-dwelling stroke survivors after first stroke, based on the International Classification of Functioning, Disability and Health (ICF), and to explore if these factors differ among older-old (75 years and older), younger-old (65–74 years), and young (18–65 years) stroke survivors.

Methods

A cross-sectional population-based national survey among community-dwelling stroke survivors, 1–2 years after their first stroke. Potential participants were approached through hospital registries. The survey had 56.2% response rate. Participants (N = 114, 50% men), 27 to 94 years old (71.6±12.9 years), were categorized as: older-old (n = 51), younger-old (n = 34) and young (n = 29). They answered questions on health, functioning and contextual factors, the Stroke Impact Scale (SIS) and the Behavioural Regulation Exercise Questionnaire-2. Descriptive analysis was used, along with analysis of variance for continuous data and Fisher´s exact tests for categorical variables. TukeyHSD, was used for comparing possible age-group pairings.

Results

The responses reflected ICF´s personal and environmental factors as well as body function, activities, and participation. Comparisons between age-groups revealed that the oldest participants reported more anxiety and depression and used more walking devices and fewer smart devices than individuals in both the younger-old and young groups. In the SIS, the oldest participants had lower scores than both younger groups in the domains of activities of daily living and mobility.

Conclusion

These findings provide important information on needs and opportunities in community-based rehabilitation for first-time stroke survivors and reveal that this population has good access to smart devices which can be used in community integration. Moreover, our results support the need for analysis in subgroups of age among the heterogenous group of older individuals in this population.
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
Authors: Hall Ross , Guedán Anabel , Yap Melvyn W. , Young George R. , Harvey Ruth , Stoye Jonathan P. , Bishop Kate N.
Published: August 2022

SARS-CoV-2 is a betacoronavirus and the etiological agent of COVID-19, a devastating infectious disease. Due to its far-reaching effect on human health, there is an urgent and growing need to understand the viral molecular biology of SARS-CoV-2 and its interaction with the host cell. SARS-CoV-2 encodes 9 predicted accessory proteins, which are presumed to be dispensable for in vitro replication, most likely having a role in modulating the host cell environment to aid viral replication. Here we show that the ORF6 accessory protein interacts with cellular Rae1 to inhibit cellular protein production by blocking mRNA export. We utilised cell fractionation coupled with mRNAseq to explore which cellular mRNA species are affected by ORF6 expression and show that ORF6 can inhibit the export of many mRNA including those encoding antiviral factors such as IRF1 and RIG-I. We also show that export of these mRNA is blocked in the context of SARS-CoV-2 infection. Together, our studies identify a novel mechanism by which SARS-CoV-2 can manipulate the host cell environment to supress antiviral responses, providing further understanding to the replication strategies of a virus that has caused an unprecedented global health crisis.
Proportionality or Rationality in Socio-Economic Rights Adjudication? Case Study of the Czech Constitutional Court’s Judgment in Compulsory Vaccination Case
Authors: Červínek Zdeněk
Published: August 2022

Proportionality represents the basic methodological approach towards constitutional rights adjudication. The million-dollar question raised in current doctrinal work is the question of its limits. One such limit concerns the applicability of the doctrine to socioeconomic rights. Since the doctrine and case law of constitutional courts do not provide clear answers in this regard, the main goal of this paper is to assess whether proportionality is a suitable method to review interferences with socio-economic rights. First, the paper discusses the theoretical aspects of this issue, primarily the paradigmatic structure of constitutional review. Second, the paper continues with a case study of the Czech Constitutional Court. In order to review interferences of these rights, the Constitutional Court applies the rationality test. The abstract definition of the test implies only means-ends analysis. Notwithstanding this, it represents an open-ended standard akin to proportionality. The paper concludes by assessing whether there are differences between these two standards of review of reasonableness.
Effect of Supplementing Ground Leaf of Misai (Orthosiphon stamineus) in Diet on Growth Performance of Broiler Chickens
Authors: Malahubban Masnindah , Zakry A A
Published: August 2022

The use of herbs in animal nutrition is one of the important approaches in overcoming the disadvantages of excessive use of artificial chemicals in animal nutrition. The present study was done to evaluate response of broilers feeding on a diet supplemented with the ground leaf of misai (Orthosiphon stamineus). The birds in this, study were 160 one-day-old male broiler chickens, given ad libitum water and feed for up to 20 days. Treatments were given to 21-day-old male broiler chickens. Data was collected and evaluated after slaughtering 42-day- male broiler chickens. It was shown that supplementing broiler diets with O. stamineus powdered leaf at a rate of 8 g/kg resulted in growth performance comparable to tetracycline and Vitamin E supplementation. It was also shown that supplementing the diet with 8 g/kg O. stamineus had a blood enzyme-lowering effect. In broilers receiving tetracycline supplementation, however, significant serum enzyme activity was observed. Results also showed that 8 g/kg of ground O. stamineus leaf in the diet was equivalent to 200 mg/kg Vitamin E supplementation. Therefore, O. stamineus leaf powder can promote organic, safe, and sustainable broiler chicken production, and as diet supplement.
The Role of Selenium in Controlling Reproductive Disorder in Beef Cattle
Authors: Wiedosari Ening , Sani Yulvian
Published: August 2022

Reproductive failure is regarded as a problem in the breeding of beef cattle as indicated by low calving rate, low conception rate, longer periods of calving interval, and neonatal mortality. Selenium deficiency may lead to non-infectious reproduction disorder in ruminants. The purpose of this review is to evaluate the role of selenium in preventing reproduction failure of beef cattle. In the reproduction process, selenium is required for cellular respiration, cellular oxidation, DNA and RNA replication, the integrity of cells membrane, and releasing free radicals. Selenocysteine (SeCys) is the main component of selenoprotein consisting of glutathione peroxidase (GPX) to inhibit free radicals formation and reduce risks of tissue damage. Glutathione peroxidases (GPXs) involved are: GPX-1 (cytosolic), GPX-2 (gastrointestinal specific), GPX-3 (plasma/extracellular), GPX-4 (phospholipid-hydroperoxides/intracellular) and GPX-5 (spermatozoa mitochondrial capsule). Selenium as an antioxidant is potentially involved in reducing fertility, stillbirth, abortus, and premature in cows based on oxidative stress and selenium deficiency. In male cattle, the role of selenium is to maintain the integrity of cells membrane, spermatozoa fertility, and ejaculation. The selenium deficiency may therefore affect spermatozoa fertility, motility, and fusion to oocytes due to lipid peroxidation. It is then regarded as a factor in reproductive failure mainly in the infertility of cattle. Treatments for reproductive failure due to selenium deficiency could be conducted by supplementing selenium in the mineral mix, periodical dosing of selenium salt, and providing Se-mineral block,  the combination of selenium and vitamin E or selenium supplementation in soils to improve the quality of fodder and feeds.
Currículo e tecnologias digitais na escolarização de jovens e adultos no Brasil: uma análise sistemática e integrativa
Authors: Jackiw Elizandra , Benvenutti Cristiane Dall’Agnol da Silva , Haracemiv Sonia Maria Chaves
Published: August 2022

O artigo tem como objetivo contribuir para a sistematização de conhecimentos sobre currículo e tecnologias digitais no campo da Educação de Jovens e Adultos no Brasil. Apresenta um mapeamento de pesquisas que tratam sobre o tema e os principais fundamentos e autores recorrentes nas produções científicas da área. Metodologicamente, caracteriza-se como um estudo bibliográfico, de abordagem qualitativa, cujo percurso metodológico inclui revisões sistemáticas e integrativas de artigos selecionados no portal de periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, entre os anos de 2007 a 2017. Ao se analisar em profundidade os artigos selecionados, evidenciou-se que a inserção de recursos tecnológicos digitais na mediação do saber e do conhecimento para jovens e adultos deve ser pensada a partir da construção de um currículo que modifique a forma de ensino rígido, fragmentado e descontextualizado, tão presente na Educação de Jovens e Adultos.
Empatia no contexto educacional: relatos de estudantes jovens e adultos
Authors: Carmo Gerson Tavares do , Souza Rozana Quintanilha Gomes
Published: August 2022

Este artigo discorre sobre a importância de valorizar a empatia no contexto educacional e, particularmente, na Educação de Jovens e Adultos. Como objetivo, pretende-se investigar como a empatia ou a falta dela na relação professor-aluno pode interferir no processo de ensino e aprendizagem. Para tanto, aplicou-se um questionário a uma turma de estudantes jovens e adultos de um campus do Instituto Federal Fluminense, que foi elaborado com base na teoria de Carl Rogers sobre o construto multidimensional da empatia, no qual inclui três componentes: cognitivo, afetivo e comportamental. Os dados obtidos revelam que, em meio a um ambiente não propício à empatia, os alunos buscam, por iniciativa própria, estratégias para criar relações empáticas com os professores para continuarem vinculados à escola.
Indicadores de avaliação do Ensino Remoto Emergencial em uma escola pública brasileira durante a pandemia de Covid-19
Authors: Ferreira Andreia de Assis , Matos Santer Alvares de , Silveira Guilherme Carvalho Franco da
Published: August 2022

É premente a necessidade de se estabelecer indicadores de avaliação para o Ensino Remoto Emergencial, possibilitando avaliá-lo e aperfeiçoá-lo, potencializando processos de ensino mais qualificados. Assim, a pesquisa se propôs a desenvolver e validar um instrumento com indicadores para avaliar, institucionalmente, a proposta de organização e oferta do Ensino Remoto Emergencial, do ponto de vista dos diferentes sujeitos de uma escola pública brasileira. A pesquisa envolveu a elaboração de indicadores, seguida da realização de grupos focais que os analisaram, sugerindo modificações. Os indicadores modificados foram submetidos, por escrito, aos sujeitos da pesquisa, que validaram as alterações. Inicialmente os indicadores eram constituídos por 58 itens, tendo havido exclusões, inclusões, reestruturações e aglutinações, culminando no instrumento final de 42 itens. Além dos produtos da pesquisa, o processo de criação, especialmente em função da metodologia empregada, se constituiu num significativo momento de reflexão de todos os sujeitos envolvidos no Ensino Remoto Emergencial.
PEIXOTO, Adão José. (Org.) Fenomenologia: diálogos possíveis. Campinas: Editora Alínea; Goiânia: Editora da PUC de Goiás, 2011. 221p.
Authors: Silva Sandra Maria Glória da , Silva Maria Aparecida da
Published: August 2022

PEIXOTO, Adão José. (Org.) Fenomenologia: diálogos possíveis. Campinas: Editora Alínea; Goiânia: Editora da PUC de Goiás, 2011. 221p.
             O livro Fenomenologia: diálogos possíveis, organizado por Adão José Peixoto, reúne artigos que abordam a aplicação dessa teoria do conhecimento como referencial para pesquisa nas áreas de Educação, Psicologia, Matemática, Enfermagem e Literatura. Apresenta os fundamentos da Fenomenologia e os procedimentos para aplicação do método fenomenológico em situações contemporâneas. Os autores propõem a ampliação do diálogo entre a Fenomenologia e outras áreas do conhecimento.
             A Fenomenologia, método de investigação filosófica elaborado por Edmund Husserl no final do século XIX, surgiu com o intuito de transpor a relação antagônica entre objetivismo e subjetivismo. Enquanto o cientificismo da filosofia positivista busca o conhecimento científico neutro e advoga o distanciamento entre o sujeito e o objeto, a Fenomenologia propõe a inseparabilidade entre o sujeito e o objeto. A perspectiva fenomenológica intenta ver além do cientificismo das ciências naturais e demonstrar a inexistência de um sujeito puro, ou seja, desvinculado do objeto. Por trás dos atos e dos fenômenos humanos observáveis, os fenomenólogos consideram a existência latente de valores, de finalidades que precisam ser interpretados e compreendidos. Assim, a Fenomenologia procura resguardar a especificidade do fenômeno humano com a intenção de evitar que as ciências humanas adquiram uma feição determinista, capaz de negar a liberdade humana.
Data de registro:12/02/2012
Data de aceite:08/02/2013
Uso de robótica en una emergencia sanitaria
Authors: Becerra Yeyson , Arbulu Saavedra Mario Ricardo
Published: August 2022

Contexto: La covid-19 ha acelerado la integración de la robótica y sistemas autónomos a los distintos sectores económicos, esto se ha presentado principalmente por la necesidad de mantener a las personas distanciadas para reducir el riesgo de contagio. En el mundo, han venido emergiendo y adaptándose diversos sistemas robóticos para ayudar a combatir la pandemia y reactivar nuevamente la economía.  
Método: Este trabajo presenta inicialmente las medidas que se han tomado en el mundo para luchar en contra de la pandemia, así como el impacto que ha dejado en la economía global. Posteriormente se seleccionan tres grupos de robots y se demarcan las principales tareas que estos han desarrollado durante dicho periodo.
Discusión: Si bien la robótica se presenta como una herramienta en la lucha contra la pandemia y un motor para reactivar la economía, se deben tener en cuenta desafíos como el remplazo de humanos por robots en ciertas labores, mayor inequidad, falta de privacidad en espacios públicos e incremento de recursos para la investigación en robótica.
Conclusiones: Se prevé un incremento en la demanda de robots para los próximos años, así como un decremento en la interacción entre humanos. El fin de la pandemia no hará retroceder la integración de los robots a los diversos sectores de la economía. La robótica es una tecnología disruptiva que hará cambiar al mundo en los próximos años.
Método: Este trabajo presenta inicialmente las medidas que se han venido tomando alrededor del mundo para luchar en contra de la pandemia, así como el impacto que ha venido dejando en la economía mundial. Posteriormente se seleccionan tres grupos de robots y se demarcan las principales tareas que estos han desarrollado durante la pandemia.
Discusión: Si bien la robótica se presenta como una herramienta en la lucha contra la pandemia y un motor para reactivar la economía, se deben tener en cuenta desafíos como tales como el remplazo de humanos por robots en ciertas labores, mayor inequidad, falta de privacidad en espacios públicos e incremento de recursos para la investigación en robótica.
Conclusiones: Se prevé un incremento en la demanda de robots para los próximos años, así como se espera un decremento en la interacción entre humanos. El fin de la pandemia no hará retroceder la integración de los robots a los diversos sectores de la economía. La robótica es una tecnología disruptiva que hará cambiar al mundo en los próximos años.
Pengaruh Lama Aerasi yang Berbeda Terhadap Pertumbuhan Populasi dan Kualitas Warna dari Kutu Air Raksasa (Daphnia magna)
Authors: Gideon Pierre Charismanuel , Sucahyo Sucahyo , Hastuti Susanti Pudji
Published: August 2022

Salah satu pakan alami yang paling baik dalam budidaya perikanan adalah D. magna yang sudah banyak dibudidayakan dan dapat diambil langsung dari alam, namun belum cukup dalam memenuhi kebutuhan. Untuk itu penelitian ini bertujuan untuk mengetahui pengaruh pertumbuhan populasi dan kualitas warna dari D. magna berdasarkan lama aerasi sehingga dapat mengetahui lama aerasi yang paling optimal untuk kultur D. magna. Penelitian ini dilaksanakan dengan membuat tiga faktor perlakuan dan satu faktor kontrol. Faktor kontrol adalah tanpa aerasi, faktor A dengan aerasi 3 jam/hari, faktor B dengan aerasi 6 jam/hari, dan faktor C dengan 24 jam aerasi. Masing – masing faktor memiliki 3 kali pengulangan. Hasil penelitian menunjukkan bahwa lama waktu aerasi 3 jam/hari adalah faktor paling optimal dalam menunjang pertumbuhan populasi D. magna dan faktor kontrol yaitu tanpa pemberian aerasi paling optimal dalam menunjang warna D. magna. Hasil analisis data dalam uji Friedman menunjukkan adanya perbedaan pengaruh pada pertumbuhan D. magna. Hasil pengukuran kualitas air menunjukan kadar DO cenderung turun bahkan melewati batas minimum, namun pada faktor C kadar DO masih dalam kadar optimal. Suhu berkisar 24.1 – 30.6 ℃ dan pH berkisar 6.3 – 7.0. Kondisi ini masih dalam kisaran optimum untuk kultur D. magna.  One of the best natural feeds in aquaculture is D. magna which has been widely cultivated and can be taken directly from nature, but is not sufficient to meet the needs. For this reason, this study aims to determine the effect of population growth and color quality of D. magna based on aeration time so that can determine the most optimal aeration time for D. magna culture. This research was conducted by making three treatment factors and one control factor. The control factor was without aeration, factor A with aeration 3 hours/day, factor B with aeration 6 hours/day, and factor C with 24 hours aeration respectively. Each factor has 3 repetitions. The results showed that aeration time of 3 hours/day was the most optimal factor in supporting the growth of D. magna population and the control factor without aeration was the most optimal in supporting the color of D. magna. The results of data analysis in the Friedman test showed there were different effect on the growth of D. magna. The results of water quality measurements show that DO levels tend to fall even past the minimum limit, but in factor C, DO levels are still in optimal levels. The measurement of temperature ranges from 24.1 – 30.6 and the pH ranges from 6.3 – 7.0. This condition was still in the optimum range for D. magna culture
Khasminskii-type theorem for a class of stochastic functional differential equations
Authors: Ma Li , Wang Ru , Yan Liangqing
Published: August 2022

This paper is concerned with the existence and uniqueness theorems for stochastic functional differential equations with Markovian switching and jump, where the linear growth condition is replaced by more general Khasminskii-type conditions in terms of a pair of Lyapunov-type functions.
Low IGF1 and high IGFBP1 predict diabetes onset in prediabetic patients
Authors: Meyer Nina M T , Kabisch Stefan , Dambeck Ulrike , Honsek Caroline , Kemper Margrit , Gerbracht Christiana , Arafat Ayman M , Birkenfeld Andreas L , Schwarz Peter E H , Machann Jürgen , Osterhoff Martin A , Weickert Martin O , Pfeiffer Andreas F H
Published: August 2022

Objectives

Some individuals develop type 2 diabetes mellitus (T2DM) despite significant metabolic improvements through lifestyle intervention. We tested the hypotheses that insulin growth factor 1 (IGF1) and its binding proteins 1 and 2 predict the onset of T2DM in prediabetes patients and determine the capacity for metabolic regeneration.

Design

We measured fasting serum IGF1, insulin growth factor-binding protein 1 (IGFBP1) and IGFBP2 in three randomized controlled lifestyle intervention trials, covering at least 1 year of intervention period and 1 year of additional follow-up.

Methods

Within a sample of 414 high-risk prediabetes patients (58% women; 28–80 years), we analyzed fasting serum concentrations of IGF1, IGFBP1 and IGFBP2 in relation to diabetes incidence and metabolic parameters over 2 years. Three hundred and forty-five subjects finished the first year of intervention.

Results

The interventions significantly improved body weight (BMI: −3.24%, P < 0.001), liver fat (−36.8%, P < 0.001), insulin sensitivity (IS) (homeostatic model assessment-insulin resistance: −6.3%, P < 0.001) and insulin secretion (disposition index: +35%, P < 0.001) in the cohort. Fourteen percent developed T2DM within 2 years. Mean IGFBP1 levels at baseline were lower in prediabetes compared to a healthy population. Also, prediabetes patients with obesity and nonalcoholic fatty liver disease had lower IGFBP1. Those with impaired glucose tolerance had higher IGFBP1 compared to those with only impaired fasting glucose. Baseline IGF1 was lower (122.5 vs 146.6 µg/L) and IGFBP1 was higher (3.32 vs 2.09 µg/L) in subjects who developed T2DM (n = 57), resulting in a significant prediction of diabetes incidence (hazard ratio (HR) IGF1: 0.991 µg/L, P = 0.003; HR IGFBP1: 1.061 µg/L, P = 0.002). This translates into a 20% and 9% difference in T2DM incidence for IGF1 and IGFBP1, respectively. Despite reduced weight, visceral fat and hepatic fat in response to 1 year of lifestyle intervention, those who developed T2DM had not improved insulin sensitivity, glucose tolerance or IGFBP1.

Conclusions

Lower IGF1 and higher IGFBP1 in prediabetes predicted the incidence of T2DM, indicating an impairment of beta-cell function, which explains the unresponsiveness to lifestyle intervention.
CURRENT PROBLEMS OF CONCLUSION OF ELECTRONIC CONTRACTS BETWEEN BUSINESS ENTITIES
Authors:   State Organization “V. Mamutov Institute of Economic and Legal Research of NAS of Ukraine”, Kyiv, Ukraine, Melikova V.I.
Published: August 2022

The article presents the results of the development of legislation governing the concept, form and procedure for concluding electronic contracts between business entities (B2B). The considered methods of concluding contracts on the Internet have already become widespread, although in the legal sense they remain poorly understood and insufficiently regulated. Therefore, it is now very important to lay the legal framework for the regulation of contractual relations on the Internet, because with the advent of new online services, there are new ways of concluding contracts. It is proposed to recognize the electronic form of contracts as a new form of contracts, other than simple written. The role of electronic digital signature in concluding electronic contracts has been established, the legislation regulating the use of electronic digital signature has been studied. It is proposed to improve the legislation of Ukraine, namely: allocation of the electronic form of the transaction in a separate, with its further division into electronic contracts concluded via the Internet using any available technical means (filling out the form in the browser / e-mail correspondence / use of managers or mobile applications) and concluded via the Internet with the obligatory use of electronic signatures.
РЕГІОНАЛЬНИЙ АСПЕКТ ВИРОБНИЦТВА ОЛІЙНИХ КУЛЬТУР В УКРАЇНІ
Authors: ЧЕХОВА Ірина
Published: August 2022

Встановлено, що олійні культури в Україні займають значне (на рівні понад 30%) місце в загальній структурі посівів сільськогосподарських культур у всіх природно-кліматичних зонах. Розглянуто зміну структури посівних площ олійних культур і динаміку їх виробництва в розрізі природно-кліматичних зон України за період 2017–2021 рр. Зафіксовано тенденцію до розширення посівів ріпака на 25% за рахунок скорочення посівів сої на 33%. Виявлено зональну спеціалізацію вирощування олійних культур в Україні. Соняшник і ріпак розміщуються в зоні Степу, соя – Лісостепу. Проаналізовано динаміку площ посіву і валових зборів ріпака, соняшнику, сої. Встановлено, що основні площі під соняшником зосереджено в Степу України (3,8 млн га), Лісостепу (2,2 млн га), Поліссі (554 тис. га), отже, динаміка є позитивною. Основні площі під соєю (757 тис. га) зосереджено в Лісостепу, в зоні Степу – 174 тис. га, в Поліссі – 390,3 тис. га, динаміка є негативною. Основні площі під ріпаком (461,5 тис. га) розміщено в зоні Степу України, у Лісостепу — 300,7 тис. га, Поліссі — 225,3 тис. га, динаміка є позитивною. Виявлено лідерів за обсягами виробництва олійних культур серед областей України, показники в яких забезпечуються за рахунок високої урожайності культур. Зроблено висновок про те, що виробництво олійних культур в Україні здійснюється інтенсивним шляхом. Перспективи подальшого розвитку виробництва олійних культур полягають у збільшенні їх валового збору за рахунок підвищення врожайності на основі впровадження сучасних сортів і гібридів рослин.
On a Small Collection of Spiders (Arachnida, Araneae) from Iraq, with New Species and Records
Authors: Zamani A. , Marusik Y.
Published: August 2022

The results of an investigation on a small collection of spiders from Najaf Province in southern Iraq are reported. Four species are described: Hersiliola babylonica sp. n. (♂♀; Hersiliidae), Liocranoeca deserticola sp. n. (♂; Liocranidae), Talanites sumericus sp. n. (♀; Gnaphosidae) and Zelotes jakesi sp. n. (♀; Gnaphosidae). Two families (Liocranidae; Miturgidae), five genera (Evippa Simon, 1882; Heriaeus Simon, 1875; Liocranoeca Wunderlich, 1999; Prochora Simon, 1886; Talanites Simon, 1893) and five species (Enoplognatha gershomi Bosmans & Van Keer, 1999; Evippa amitaii Armiach Steinpress et al., 2021; Heriaeus buffoni (Audouin, 1826); Prochora lycosiformis (O. Pickard-Cambridge, 1872); Thanatus vulgaris Simon, 1870) are recorded in Iraq for the first time; for E. gershomi, the epigyne is described for the first time, the male is redescribed and the species is newly reported also from Turkmenistan, Kazakhstan and Uzbekistan.
Acaridid Mite Species Communities in Agricultural and Industrial Objects of Storing and Concentration of Nutritive Substrates in Zhytomyr Polissia
Authors: Oksentiuk Ya. R. , Liashevych A. M. , Lupaina I. S.
Published: August 2022

This work presents the results of long-term complex study of acaridid mites’ fauna and ecology in different biotopes (agricultural and industrial objects) in Zhytomyr Polissia. There were 30 species identified, which belong to five families: Suidasidae, Acaridae, Glycyphagidae, Chortoglyphidae, Aeroglyphidae. The results showed that acarocomplex of industrial objects, like mills, granaries and warehouses, includes the 11 Acaridae species, and that of compound fodder factories — three species. Acarofauna of agricultural objects was shown to consist of 30 species: 21 in barns with animal feed (grains, compound feeds, hay and straw), 12 in outbuildings with livestock and poultry, 9 in beehives, 13 in vegetable storages. The qualitative differences of mentioned acarocomplexes were established, and the factors to possibly influence their dynamics were discussed.
Infection of Dice Snake (Reptilia, Colubridae) with Larvae of Eustrongylides excisus (Nematoda, Dioctophymatidae) in the Middle and Lower Dnipro River Basin
Authors: Yermolenko S. V. , Gasso V. A. , Hahut A. M. , Spirina V. A.
Published: August 2022

Dice snakes can be a paratenic host for a stage IV of Eustrongylides excisus, Jägerskiöld, 1909 larva due to specific diet of the snakes. The infection rate of E. excisus in Natrix tessellata (Laurenti, 1768) was studied in the basin of the middle and the lower Dnipro River in 2013–2017. We searched for nematodes in snakes from four sites: Prydniprovska Thermal Power Station, Majorova Balka, Zaporizhzhia; National Nature Park Velykyi Luh. The snakes from all studied areas had high prevalence of infection (more than 90 %). The lowest level of intensity (2.50 ± 0.60) and abundance (2.27 ± 0.58) were in ecosystems near Prydniprovska ТPP. There was no significant difference between infection parameters in snakes from other groups. Capsules with larva localized in the gastrointestinal tract, liver, muscles, and lung. The most infected organ was the liver, statistical analysis showed significant differences with other organs. The lowest infection was found in the lung. Environmental pollution of the Dnipro River waters with pesticides and other pollutants accompanied by a climate change may influence on the E. excisus life cycle that needs additional studies.
Insurance and Health Care Outcomes in Regions Where Undocumented Children Are Medicaid-Eligible
Authors: Rosenberg Julia , Shabanova Veronika , McCollum Sarah , Sharifi Mona
Published: August 2022

OBJECTIVES

Expansion of insurance eligibility is associated with positive health outcomes. We compared uninsurance and health care utilization for (1) all children, and (2) children in immigrant families (CIF) and non-CIF who resided inside and outside of the seven US states/territories offering public health insurance to children regardless of documentation status (“extended-eligibility states/territories”).

METHODS

Using the cross-sectional, nationally representative National Survey of Children’s Health-2019, we used survey-weighted, multivariable Poisson regression to assess the association of residence in nonextended- versus extended-eligibility states/territories with uninsurance and with health care utilization measures for (1) all children, and (2) CIF versus non-CIF, adjusting for demographic covariates.

RESULTS

Of the 29 433 respondents, the 4035 (weighted 27.2%) children in extended- versus nonextended-eligibility states/territories were more likely to be CIF (27.4% vs 20.5%, P < .001), 12 to 17 years old (37.2% vs 33.2%, P = .048), non-White (60.1% vs 45.9%, P < .001), and have a non-English primary language (20.6% vs 11.1%, P < .001).

The relative risk of uninsurance for children in nonextended- versus extended-eligibility states/territories was 2.0 (95% confidence interval 1.4–3.0), after adjusting for covariates. Fewer children in extended- versus nonextended-eligibility states/territories were uninsured (adjusted prevalence 3.7% vs 7.5%, P < .001), had forgone medical (2.2% vs 3.1%, P = .07) or dental care (17.1% vs 20.5%, P = .02), and had no preventive visit (14.3% vs 17.0%, P = .04). More CIF than non-CIF were uninsured, regardless of residence in nonextended- versus extended-eligibility states/territories: CIF 11.2% vs 5.7%, P < .001; non-CIF 6.1% vs 3.1% P < .001.

CONCLUSIONS

Residence in nonextended-eligibility states/territories, compared with in extended-eligibility states/territories, was associated with higher uninsurance and less preventive health care utilization.
Discovery of Aedes (Ochlerotatus) pionips Dyar, 1919 (Diptera, Culicidae) in Germany
Authors: Kuhlisch Cornelius
Published: August 2022

A group of black-legged mosquito species within the subgenus Ochlerotatus Lynch Arribalzaga, 1891 of the genus Aedes Meigen, 1818 is difficult to identify based on their morphology. This group includes Aedes pionips Dyar, 1919, whose first record in the Erzgebirge (Germany) is reported in this study. The objective was to compile and add species specific characters for the morphological discrimination of Ae. pionips from similar mosquitoes in order to facilitate species identification. Generated cytochrome c oxidase subunit I gene DNA sequences of Ae. pionips from Germany were compared to sequences from related species, using a phylogenetic tree.
Współczesne teorie piękna i decorum. Wybór poglądów XX wieku
Authors:   Katolicki Uniwersytet Lubelski Jana Pawła II, Lublin, Polska, Klauza Karol
Published: August 2022

The aim of this study is an attempt to continue the discussion started by the extremely useful and competent synthesis of views on the relations between art and matter, presented in the article “The Transformations of the Symbolic and Theological Meaning of Matter Reflected in Christian Aesthetics and Art” by Janusz Krolikowski. Since the 16th century, European thought on the nature of beauty has been marked by interpretations that draw on the achievements of many academic disciplines. Numerous secular views on aesthetics were expressed in the period between the Baroque and positivism, and the ecclesiastical ones between the era of post-Tridentine theology to the time of accomodata renovatio of the Second Vatican Council and the concept of culture born out of it. Philosophers and art historians, especially of the nineteenth century, sought new justifications for changing views on beauty and its role in building the generational identity of the human being. In the field of philosophy, the views of George Berkeley and Immanuel Kant, among others, are experiencing a renaissance, and in religious thought, the same is true for the views of Joseph Ratzinger, prefect of the Congregation for the Doctrine of the Faith during the pontificate of John Paul II, concretised by the thought of Hans Urs von Balthasar. They correspond with the ideological inspirations of contemporary artists. Christian Churches undertake a dialogue with them in their Magisterium. In this way they develop elements of Christian aesthetics. Polish researchers have also made their contributions to this field.