bluuebunny/crossref_metadata_2025 huggingface dataset:
Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine
Authors: Wang Mengyun , Gao Yang , Qu Pengxiang , Qing Suzhu , Qiao Fang , Zhang Yong , Mager Jesse , Wang Yongsheng
Published: October 2017

Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and proteins may be one important factor contributing to developmental failure in somatic cell cloned embryos. In the present study, we found microRNA-449b (miR-449b) was highly expressed in sperm. Target gene predictions and experimental verification indicate that several embryonic development-related genes, including CDK6, c-MYC, HDAC1 and BCL-2, are targets of miR-449b. We therefore investigated the role of miR-449b using somatic cell nuclear transfer (SCNT) embryo model. Bovine fetal fibroblasts, expressing miR-449b through a doxycycline (dox) induced expression system were used as nuclear donor cells for SCNT. The results showed that miR-449b expression in SCNT embryos significantly enhanced the cleavage rate at 48 h after activation and the levels of H3K9 acetylation at the 2-cell to 8-cell stages, meanwhile, significantly decreased the apoptosis index of blastocysts. In addition, we verified miR-449b could regulate the expression levels of CDK6, c-MYC, HDAC1 and BCL-2. In conclusion, the present study shows that miR-449b expression improves the first cleavage division, epigenetic reprogramming and apoptotic status of bovine preimplantation cloned embryos.
School-based assessment of amblyopia and strabismus among multiethnic children in rural China
Authors: Pan Chen-Wei , Chen Xuejuan , Zhu Hui , Fu Zhujun , Zhong Hua , Li Jun , Huang Dan , Liu Hu
Published: October 2017

We aimed to determine the prevalence and possible ethnic variations in strabismus and amblyopia among multiethnic school-aged children in rural China. A total of 9,263 children (4,347 Han, 3,352 Yi, 799 Dai and 765 Bai) aged 6 to 14 years were analyzed. Comprehensive eye examinations including monocular distance visual acuity, anterior segment examination, autorefraction, cover testing and ocular motility were conducted. Manifested strabismus was detected in 3.53% of the overall population. The prevalence of strabismus was 3.29% in Han, 4.12% in Yi, 2.25% in Dai, and 3.66% in Bai ethnic groups with marginally inter-ethnic differences (P = 0.046). There was an increasing trend in the prevalence of strabismus with increasing age (P < 0.001). Amblyopia affected 132 children (1.43%) overall, with no statistical differences in gender and age. The prevalence of amblyopia was highest in Dai ethnic group (2.00%) and lowest in ethnic Yi ethnic group (1.04%) with no significant difference being detected (P = 0.062). Refractive error and strabismus were the two major factors associated with amblyopia. No significant ethnic differences in strabismus and amblyopia among Chinese ethnic minorities were observed. Refractive error and strabismus were the major causes for amblyopia in rural Chinese children.
Dysfunctional Early Processing of Facial Expressions in Hazardous Drinkers: Evidence from an ERP Study
Authors: Zhang Hui , Jin Yi , Chan John S. Y. , Yang Feng-Chi , Cui Fang
Published: October 2017

Chronic alcohol intoxication impairs multiple cognitive functions. According to the dual system model (DSM), the development of alcohol dependence (AD) involves the imbalance between the automatic-affective system and the reflective system. However, the cognitive functions of non-AD hazardous drinkers (HDs) remain unclear. The present study aimed to explore how the HDs process facial expressions differently from the healthy subjects. Sixteen HDs and seventeen control subjects (CSs) completed an emotional working memory (WM) task while the electroencephalogram (EEG) was recorded. We found that there was no significant group difference in behavioral performance between the two groups. In the ERP data, relative to the CSs, the HDs showed delayed latencies of P1 and N170. Moreover, the CSs showed significant differences between the amplitudes of neural/fear and disgust expressions while these differences were insignificant in the HDs. The current results suggest that the main deficits in the processing of facial expression in HDs existed in the early automatic-affective system instead of in the reflective system.
Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues
Authors: Parra Edwin R. , Uraoka Naohiro , Jiang Mei , Cook Pamela , Gibbons Don , Forget Marie-Andrée , Bernatchez Chantale , Haymaker Cara , Wistuba Ignacio I. , Rodriguez-Canales Jaime
Published: October 2017

Immune-profiling is becoming an important tool to identify predictive markers for the response to immunotherapy. Our goal was to validate multiplex immunofluorescence (mIF) panels to apply to formalin-fixed and paraffin-embedded tissues using a set of immune marker antibodies, with the Opal™ 7 color Kit (PerkinElmer) in the same tissue section. We validated and we described two panels aiming to characterize the expression of PD-L1, PD-1, and subsets of tumor associated immune cells. Panel 1 included pancytokeratin (AE1/AE3), PD-L1, CD4, CD8, CD3, CD68, and DAPI, and Panel 2 included pancytokeratin, PD-1, CD45RO, granzyme B, CD57, FOXP3, and DAPI. After all primary antibodies were tested in positive and negative controls by immunohistochemistry and uniplex IF, panels were developed and simultaneous marker expressions were quantified using the Vectra 3.0™ multispectral microscopy and image analysis InForm™ 2.2.1 software (PerkinElmer).These two mIF panels demonstrated specific co-localization in different cells that can identify the expression of PD-L1 in malignant cells and macrophages, and different T-cell subpopulations. This mIF methodology can be an invaluable tool for tumor tissue immune-profiling to allow multiple targets in the same tissue section and we provide that is accurate and reproducible method when is performed carefully under pathologist supervision.
IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8+ T cells
Authors: Li Lei , Jay Steven M. , Wang Yan , Wu Shu-Wei , Xiao Zhengguo
Published: October 2017

An effective cytotoxic T lymphocyte (CTL) response against intracellular pathogens is generally accomplished by immense CTL expansion and activation, which can destroy infected cells. Vigorous immune responses can lead to activation of bystander CD8+ T cells, but the contribution from antigen-specific CTLs is not well understood. We found that CTLs secrete extracellular vesicles following antigen stimulation. These CTL-derived vesicles contain CTL proteins and exhibit markers and size profiles consistent with exosomes. Interestingly, further stimulation of CTLs with IL-12 impacts exosome size and leads to selective enrichment of certain exosomal proteins. More important, exosomes from IL-12-stimulated CTLs directly activated bystander naïve CD8+ T cells to produce interferon-γ (IFNγ) and granzyme B (GZB) in the absence of antigens, whereas control exosomes derived from antigen-stimulated CTLs did not. In addition, IL-12 induced exosomes are able to strengthen the effects of weak antigen stimulation on CTLs. Proteomic analysis demonstrates that IL-12 stimulation alters catalytic and binding activities of proteins in CTL exosomes. Our findings indicate that the biological function and morphology of exosomes secreted by CTLs can be influenced by the type of stimulation CTLs receive. Thus, a fully functional, ongoing, antigen-specific CTL response may influence bystander CD8+ T cells through secretion of exosomes.
Computational Analysis of the Molecular Mechanism of RamR Mutations Contributing to Antimicrobial Resistance in Salmonella enterica
Authors: Liu Yen-Yi , Chen Chih-Chieh
Published: October 2017

Antimicrobial resistance (AMR) in pathogenic microorganisms with multidrug resistance (MDR) constitutes a severe threat to human health. A major causative mechanism of AMR is mediated through the multidrug efflux pump (MEP). The resistance-nodulation-division superfamily (RND family) of Gram-negative bacteria is usually the major cause of MDR in clinical studies. In Salmonella enterica, the RND pump is translated from the acrAB gene, which is regulated by the activator RamA. Many MEP-caused AMR strains have high ramA gene expression due to mutations in RamR, which has a homodimeric structure comprising the dimerization domain and DNA-binding domain (DBD). Three mutations on the dimerization domain, namely Y59H, M84I, and E160D, are far from the DBD; the molecular mechanism through which they influence RamR’s binding affinity to the ramA gene promoter and consequently disrupt RamA remains unclear. The present study conducted molecular dynamics simulations, binding free energy calculations, and normal mode analysis to investigate the mechanism through which Y59H, M84I, and E160D mutations on the dimerization domain influence the binding affinity of RamR to the ramA promoter. The present results suggest that the three mutations alter the RamR structure, resulting in decreased DNA-binding affinity.
An ultrasensitive sandwich immunoassay with a glucometer readout for portable and quantitative detection of Cronobacter sakazakii
Authors: Ye Lingxian , Zhao Guangying , Dou Wenchao
Published: October 2017

A new immunoassay for the detection of C. sakazakii was developed using PGM, antibodies and glucose oxidase coated silica nanoparticles and immune magnetic nanoparticles.
Sequential growth of CaF2:Yb,Er@CaF2:Gd nanoparticles for efficient magnetic resonance angiography and tumor diagnosis
Authors: Liu Kun , Yan Xu , Xu Yun-Jun , Dong Liang , Hao Li-Na , Song Yong-Hong , Li Fei , Su Yang , Wu Ya-Dong , Qian Hai-Sheng , Tao Wei , Yang Xian-Zhu , Zhou Wei , Lu Yang
Published: October 2017

It is a significant challenge to develop nanoscale magnetic resonance imaging (MRI) contrast agents with high performance of relaxation.
Resistive memory devices based on a triphenylamine-decorated non-precious cobalt(ii) bis-terpyridine complex
Authors: Tang Jian-Hong , Sun Tian-Ge , Shao Jiang-Yang , Gong Zhong-Liang , Zhong Yu-Wu
Published: October 2017

The sandwiched devices of a cobalt(ii) bis-terpyridine complex display appealing flash-type resistive switching (ON/OFF >103; voltage <±3 V).
Copper(i)-catalysed asymmetric allylic reductions with hydrosilanes
Authors: Nguyen T. N. Thanh , Thiel Niklas O. , Teichert Johannes F.
Published: October 2017

The copper(i)-catalysed asymmetric allylic reduction enables a regio- and stereoselective transfer of a hydride nucleophile in an SN2′-fashion onto allylic bromides.
Unprecedented magnetic behaviour in lanthanide-based ionic liquids
Authors: Monson Todd C. , Stevens Tyler E. , Leger Jean L. , Manson Jamie L. , Lovejoy Katherine S. , Newsham Aimee L. , Del Sesto Rico E.
Published: October 2017

Ionic liquids containing lanthanide halide anions give the opportunity to investigate magnetic behaviour in non-ordered systems.
Acid/base-controllable fluorescent molecular switches based on cryptands and basic N-heteroaromatics
Authors: Cheng Ming , Zhang Jing , Ren Xintong , Guo Shuwen , Xiao Tangxin , Hu Xiao-Yu , Jiang Juli , Wang Leyong
Published: October 2017

Two kinds of fluorescent BMP32C10-based cryptands1and2have been developed.
Rapid synthesis of hierarchical, flower-like Ag microstructures with a gemini surfactant as a directing agent for SERS applications
Authors: Xia Yan , Gao Zhinong , Liao Xueming , Pan Chenchen , Zhang Yingfang , Feng Xuesong
Published: October 2017

Various hierarchical Ag microstructures, including sensitive SERS substrate flower-like structures, can be designed and rapidly synthesized under different conditions.
A Zn(ii) complex with large channels based on 3′-nitro-biphenyl-3,5,4′-tricarboxylic acid: synthesis, crystal structure, fluorescence sensing of ATP, ADP, GTP, and UTP in aqueous solution and drug delivery
Authors: Zhang De-chun , Li Xia
Published: October 2017

A 3D Zn(ii)–MOF with large cubic channels was synthesized. It showed fluorescence sensing of ATP, ADP, GTP, and UTP. Furthermore, it exhibited a remarkable capacity for and controlled release of 5-fluorouracil.
Stacking-enriched magneto-transport properties of few-layer graphenes
Authors: Do Thi-Nga , Chang Cheng-Peng , Shih Po-Hsin , Wu Jhao-Ying , Lin Ming-Fa
Published: October 2017

The quantum Hall effects in sliding bilayer graphene and a AAB-stacked trilayer system are investigated using the Kubo formula and the generalized tight-binding model.
Cancer classification with a network of chemical oscillators
Authors: Gizynski Konrad , Gorecki Jerzy
Published: October 2017

We discuss chemical information processing considering dataset classifiers formed with a network of interacting droplets.
Interplay of twist angle and solvents with two-photon optical channel interference in aryl-substituted BODIPY dyes
Authors: Alam Md. Mehboob , Misra Ramprasad , Ruud Kenneth
Published: October 2017

The destructive two-photon optical channel interference in BODIPY dyes can be turned to constructive by changing either the solvent or the dihedral angle.
Fluorescent chemosensors: the past, present and future
Authors: Wu Di , Sedgwick Adam C. , Gunnlaugsson Thorfinnur , Akkaya Engin U. , Yoon Juyoung , James Tony D.
Published: October 2017

Fluorescent chemosensors for ions and neutral analytes have been widely applied in many diverse fields such as biology, physiology, pharmacology, and environmental sciences.
Beyond soft chemistry – bulk and surface modifications of polycrystalline lepidocrocite titanate induced by post-synthesis thermal treatment
Authors: Maluangnont Tosapol , Chanlek Narong , Suksawad Thitiporn , Tonket Nisarat , Saikhamdee Panwarot , Sukkha Usa , Vittayakorn Naratip
Published: October 2017

Increased interlayer expansion and reduction of layered charge density in lepidocrocite-titanate.
Unusual differences in the reactivity of glutamic and aspartic acid in oxidative decarboxylation reactions
Authors: But Andrada , van der Wijst Evie , Le Nôtre Jérôme , Wever Ron , Sanders Johan P. M. , Bitter Johannes H. , Scott Elinor L.
Published: October 2017

Chemically similar acidic amino acids present remarkable differences in reactivity under oxidative decarboxylation conditions for the production of biobased nitriles.
Using recyclable pH-responsive lignin amphoteric surfactant to enhance the enzymatic hydrolysis of lignocelluloses
Authors: Cai Cheng , Zhan Xuejuan , Zeng Meijun , Lou Hongming , Pang Yuxia , Yang Jia , Yang Dongjie , Qiu Xueqing
Published: October 2017

Adding recyclable pH-responsive lignin amphoteric surfactant (SLQA) can enhance enzymatic hydrolysis and enable the comprehensive utilization of lignocelluloses.
Isotachophoresis applied to biomolecular reactions
Authors: Eid C. , Santiago J. G.
Published: October 2017

This review discusses research developments and applications of isotachophoresis (ITP) to the initiation, control, and acceleration of chemical reactions, emphasizing reactions involving biomolecular reactants such as nucleic acids, proteins, and live cells.
The use of matched molecular series networks for cross target structure activity relationship translation and potency prediction
Authors: Keefer Christopher E. , Chang George
Published: October 2017

Matched molecular series (MMS) network for PDE2A, DGAT1, and HCV showing the relationships between shared MMS/target combinations.
Experimental and theoretical investigation of the high dielectric permittivity of tantalum doped titania
Authors: Anithakumari Palavalasa , Prasad Mandal Balaji , Nigam Sandeep , Majumder Chiranjib , Mohapatra Manoj , Kumar Tyagi Avesh
Published: October 2017

High dielectric permittivity is observed due to conducting grains and insulating grain boundaries.
A convenient and label-free colorimetric assay for dopamine detection based on the inhibition of the Cu(ii)-catalyzed oxidation of a 3,3′,5,5′-tetramethylbenzidine–H2O2 system
Authors: Wang Hai-Bo , Li Yang , Dong Gao-Li , Gan Tian , Liu Yan-Ming
Published: October 2017

A convenient and label-free colorimetric assay was reported for dopamine detection based on the inhibition of the Cu2+ catalyzed oxidation of a TMB–H2O2 system.
Visible-light-responsive catalysis of a zinc-introduced lacunary disilicoicosatungstate for the deoxygenation of pyridine N-oxides
Authors: Jeong Jinu , Suzuki Kosuke , Yamaguchi Kazuya , Mizuno Noritaka
Published: October 2017

A mononuclear zinc-introduced lacunary disilicoicosatungstate showed efficient photocatalytic activity in the selective deoxygenation of pyridine N-oxides under visible light irradiation.
Ultrathin graphene nanosheets derived from rice husks for sustainable supercapacitor electrodes
Authors: Sankar S. , Lee Hwauk , Jung Hyun , Kim Aran , Ahmed Abu Talha Aqueel , Inamdar Akbar I. , Kim Hyungsang , Lee Sejoon , Im Hyunsik , Young Kim Deuk
Published: October 2017

Ultrathin graphene nanosheets were derived from rice husks via KOH activation and they showed excellent electrochemical performances.
Facile fabrication of PS/Fe3O4@PANi nanocomposite particles and their application for the effective removal of Cu2+
Authors: Li Yunxing , Qiu Ji , Ye Sunjie , Wang Likui , Yang Cheng , Sun Peidong , Wang Chuanxi
Published: October 2017

Herein we reported a facile approach to fabricating polystyrene/Fe3O4@polyaniline nanocomposite particles with high adsorption capacity and good recyclability for Cu2+.
Characterization of carboxylate nanoparticle adhesion with the fungal pathogen Candida albicans
Authors: Lyden Amy , Lombardi Lisa , Sire Wilfried , Li Peng , Simpson Jeremy C. , Butler Geraldine , Lee Gil U.
Published: October 2017

Carboxylate nanoparticles bind strongly to hyphal adhesin Als3 ofCandida albicansand the interaction is related to the physiochemical properties of particles.
Biocompatible silver, gold and silver/gold alloy nanoparticles for enhanced cancer therapy: in vitro and in vivo perspectives
Authors: Shanmugasundaram Thangavel , Radhakrishnan Manikkam , Gopikrishnan Venugopal , Kadirvelu Krishna , Balagurunathan Ramasamy
Published: October 2017

Actinobacterially synthesised silver, gold and silver/gold alloy nanoparticles for enhancedin vitroandin vivocancer therapy.
A Ni(OH)2–CoS2 hybrid nanowire array: a superior non-noble-metal catalyst toward the hydrogen evolution reaction in alkaline media
Authors: Chen Lanlan , Zhang Jiayu , Ren Xiang , Ge Ruixiang , Teng Wanqing , Sun Xuping , Li Xuemei
Published: October 2017

A Ni(OH)2–CoS2 nanowire array on a carbon cloth acts as a 3D catalyst electrode for a hydrogen evolution reaction, with only 99 mV overpotential to drive 20 mA cm−2 in 1.0 M KOH, 100 mV less than that of a CoS2 nanoarray.
Ultra-sensitive near-infrared graphene photodetectors with nanopillar antennas
Authors: Liu Yu , Huang Wen , Gong Tianxun , Su Yue , Zhang Hua , He Yiwen , Liu Zhiwei , Yu Bin
Published: October 2017

Graphene has been demonstrated as a candidate for optoelectronic devices due to its broad absorption spectrum and ultra-high carrier mobility.
A small graphene oxide sheet/polyvinylidene fluoride bilayer actuator with large and rapid responses to multiple stimuli
Authors: Xu Guochuang , Zhang Miao , Zhou Qinqin , Chen Hongwu , Gao Tiantian , Li Chun , Shi Gaoquan
Published: October 2017

A high-performance actuator should be able to deliver large-shape deformations, fast actuations and sensitive responses to multiple stimuli.
A thiol-free synthesis of alkynyl chalcogenides by the copper-catalyzed C–X (X = S, Se) cross-coupling of alkynyl carboxylic acids with Bunte salts
Authors: Liu Fanmin , Yi Wenbin
Published: October 2017

A thiol-free protocol is developed for the copper-catalyzed C–X (X = S, Se) cross-coupling of alkynyl carboxylic acids with Bunte salts.
Synthesis of mono- and di-arylated acenaphthylenes and programmed access to dibenzo[j,l]fluoranthenesviapalladium-catalysed C–H bond functionalisation
Authors: Shi Xinzhe , Roisnel Thierry , Soulé Jean-François , Doucet Henri
Published: October 2017

Access to symmetrical and non-symmetrical C1,C2-diarylated acenaphthylenes and to dibenzo[j,l]fluoranthenes using programmed Pd-catalysed C–H bond functionalization.
Facile green synthesis of nanomagnets for modulating magnetohyperthermia: tailoring size, shape and phase
Authors: Silva M. P. , Drummond A. L. , Aquino V. R. R. , Silva L. P. , Azevedo R. B. , Sales M. J. A. , Morais P. C. , Bakuzis A. F. , Sousa M. H.
Published: October 2017

Isometric and anisometric iron oxide magnetic nanoparticles, synthesized via an eco-friendly route, present modulated heating efficiency for magnetic hyperthermia applications.
A Raman spectro-microscopic investigation of ETFE-based radiation-grafted anion-exchange membranes
Authors: Lee Wai Hin , Crean Carol , Varcoe John R. , Bance-Soualhi Rachida
Published: October 2017

Raman spectro-microscopy on a radiation-grafted anion-exchange membrane detected alkali degradation throughout its cross-section that quantitatively matched loss of ion-exchange capacity.
Anthocyanins from black wolfberry (Lycium ruthenicum Murr.) prevent inflammation and increase fecal fatty acid in diet-induced obese rats
Authors: Yin Jinjin , Wu Tao
Published: October 2017

This study aimed to determine whether black wolfberry (Lycium ruthenicumMurr.) anthocyanin (BWA) consumption can alleviate oxidative stress and reduce inflammation in high-fat diet-induced obese male Sprague-Dawley rats.
Restorable, high-strength poly(N-isopropylacrylamide) hydrogels constructed through chitosan-based dual macro-cross-linkers with rapid response to temperature jumps
Authors: Ma X. M. , Li R. , Ren J. , Lv X. C. , Zhao X. H. , Ji Q. , Xia Y. Z.
Published: October 2017

Thermo-responsive, high mechanical poly(N-isopropylacrylamide) hydrogels with excellent recoverability and rapid response rate are constructed on chitosan-based dual macro-cross-linkers.
Biofunctionalisation of p-doped silicon with cytochrome c553minimises charge recombination and enhances photovoltaic performance of the all-solid-state photosystem I-based biophotoelectrode
Authors: Janna Olmos Julian David , Becquet Philippe , Gront Dominik , Sar Jarosław , Dąbrowski Andrzej , Gawlik Grzegorz , Teodorczyk Marian , Pawlak Dorota , Kargul Joanna
Published: October 2017

Passivation of p-doped silicon substrate was achieved by its biofunctionalisation with hexahistidine-tagged cytochrome c553, a soluble electroactive photosynthetic protein responsible for electron donation to photooxidised photosystem I.
Does Flory–Rehner theory quantitatively describe the swelling of thermoresponsive microgels?
Authors: Lopez Carlos G. , Richtering Walter
Published: October 2017

The polymer volume fraction of PNIPAM microgels in the collapsed state is estimated to be ≃0.44, independent of cross linking or molar mass. The Flory–Rehner model can accurately describe microgel swelling, but the accuracy of the obtained fit parameters is significantly poorer.
Programming the mechanics of cohesive fiber networks by compression
Authors: Vos Bart E. , Liebrand Luka C. , Vahabi Mahsa , Biebricher Andreas , Wuite Gijs J. L. , Peterman Erwin J. G. , Kurniawan Nicholas A. , MacKintosh Fred C. , Koenderink Gijsje H.
Published: October 2017

We report that networks of the biopolymer fibrin can be reinforced by compression–decompression through strain-induced bonds mediated by stress build-up in the network.
Reply to the ‘Comment on “Relating side chain organization of PNIPAm with its conformation in aqueous methanol”’ by A. Pica and G. Graziano, Soft Matter, 2017, 13, DOI: 10.1039/C7SM01065F
Authors: Mukherji Debashish , Wagner Manfred , Watson Mark D. , Winzen Svenja , de Oliveira Tiago E. , Marques Carlos M. , Kremer Kurt
Published: October 2017

We address on scientific grounds issues raised by a comment on our article in Soft Matter, 2016, 12, 7995, showing why requests to reinterpret our data do not hold.
Direct conversion of CO2to meso/macro-porous frameworks of surface-microporous graphene for efficient asymmetrical supercapacitors
Authors: Chang Liang , Stacchiola Dario J. , Hu Yun Hang
Published: October 2017

Meso/macro-porous frameworks of surface-microporous graphene are synthesized for excellent asymmetrical AC//MFSMG capacitors.
Seed mediated copper nanoparticle synthesis for fabricating oxidation free interdigitated electrodes using intense pulse light sintering for flexible printed chemical sensors
Authors: Ankireddy Krishnamraju , Druffel Thad , Vunnam Swathi , Filipič Gregor , Dharmadasa Ruvini , Amos Delaina A.
Published: October 2017

A facile aqueous-based seed-mediated chemical reduction method is developed for the synthesis of copper nanoparticles.
Controlled synthesis of sponge-like porous Au–Ag alloy nanocubes for surface-enhanced Raman scattering properties
Authors: Zhang Tao , Zhou Fei , Hang Lifeng , Sun Yiqiang , Liu Dilong , Li Huilin , Liu Guangqiang , Lyu Xianjun , Li Cuncheng , Cai Weiping , Li Yue
Published: October 2017

The sponge-like Au–Ag alloy nanocubes (NCs) showed excellent SERS performance derived from high-density “hotspots” in nanopores, sharp corners and edges, and synergistic effect between Au and Ag species.
Logic operation‐based Design for Testability method and parallel test algorithm for 1T1R crossbar
Authors: Liu Peng , You Zhiqiang , Kuang Jishun , Elimu Michael , Cai Shuo , Wang Weizheng
Published: October 2017

Among resistive random access memory (RRAM) architectures, one transistor one memristor (1T1R) crossbar is the most fledged one. For 1T1R crossbar, a logic operation‐based Design for Testability and parallel test algorithm, which is an improvement of March C*‐1T1R test algorithm, are proposed. The pass‐fail fault dictionary of the proposed test algorithm is analysed. Analytical results show that the proposed test algorithm can detect all the modelled faults caused by the parametric variation of memristors and traditional RAM. Compared with March MOM, March C* and March C*‐1T1R, the test time of the proposed test algorithm is reduced with a little area overhead for a large size crossbar.
Demonstration of fully vertical GaN‐on‐Si Schottky diode
Authors: Zhang K. , Mase S. , Nakamura K. , Hamada T. , Egawa T.
Published: October 2017

The realisation of a fully vertical gallium nitride (GaN)‐on‐silicon (Si) Schottky barrier diode (SBD) without using wafer bonding and Si substrate removal process is reported. The SBD presented a turn‐on voltage of 0.69 V at 1 A/cm2, breakdown voltage of 148 V with a specific on‐resistance of 13.9 mΩ cm2. The ideality factor and Schottky barrier height were 1.35 and 0.71 eV, respectively. An effective critical electric field was estimated to be 1.48 MV/cm. The Baliga's figure of merit for the SBD was calculated to be 1.57 MW/cm2. These results indicate the great potential of GaN‐on‐Si in achieving cost‐effective fully vertical power device.
Balanced UWB power divider with one narrow notch‐band
Authors: Wei Feng , Zhao Xi Bei , Wang Xin Yi , Li Bin , Shi Xiao Wei
Published: October 2017

A compact and simple differential ultra wideband (UWB) equal power divider (PD) with one narrow notch‐band is presented. The proposed PD is based on slotline resonators and balanced stepped‐impedance microstrip‐to‐slotline transition structures. A wide differential‐mode (DM) impedance bandwidth covering from 1.8 to 11.5 GHz can be achieved. Besides, independent common‐mode (CM) responses with a larger bandwidth and higher suppression can be obtained. It is noted that the DM passbands are independent from the CM responses, which significantly simplify the design procedure. In addition, a narrow and sharp DM notched band from 5.8 to 5.9 GHz is generated by adding one pair of quarter‐wavelength short‐circuited stubs next to the microstrip line symmetrically. In order to illustrate the effectiveness of the design, a prototype is fabricated and measured. A good agreement between the simulated and measured results is observed. To the best of authors’ knowledge, the proposed balanced UWB PD is the first ever reported.
Fault recovery for cascaded asynchronous sequential machines
Authors: Yang Jung‐Min , Kwak Seong Woo
Published: October 2017

In this study, the authors investigate the fault‐tolerant control problem of a cascaded asynchronous sequential machine (ASM) in which two ASMs subject to adversarial inputs constitute a cascade composition. The main objective is to develop a corrective controller that can diagnose and tolerate any unauthorised state transition occurring in the cascaded machine. In particular, the authors address fault‐tolerant control for two control configurations, one with a state feedback and the other with an output feedback. The existence condition for a controller is found to be different with respect to each feedback availability. The authors apply the proposed control scheme to robust operations of memory scrubbing modules in space‐borne computers implemented on field‐programmable gate array systems. Experimental results show the practicability of the proposed methodology.
Automatic detection of individual and touching moths from trap images by combining contour‐based and region‐based segmentation
Authors: Bakkay Mohamed Chafik , Chambon Sylvie , Rashwan Hatem A. , Lubat Christian , Barsotti Sébastien
Published: October 2017

Insect detection is one of the most challenging problems of biometric image processing. This study focuses on developing a method to detect both individual insects and touching insects from trap images in extreme conditions. This method is able to combine recent approaches on contour‐based and region‐based segmentation. More precisely, the two contributions are: an adaptive k‐means clustering approach by using the contour's convex hull and a new region merging algorithm. Quantitative evaluations show that the proposed method can detect insects with higher accuracy than that of the most used approaches.
Analysis, design and experimental verification of a coaxial magnetic gear using stationary permanent‐magnet ring
Authors: Li Xianglin , Cheng Ming , Wang Yubin
Published: October 2017

This study presents the analysis and experimental verification of a coaxial magnetic gear (CMG) for speed‐change transmission. The key design of this CMG is to adopt a stationary permanent‐magnet (PM) ring between the inner and outer rotors, aiming at removing the PMs and only retaining the salient‐pole‐iron on the outer rotor to improve its mechanical reliability. Meanwhile, due to a large equivalent magnetic clearance promoting low torque ripples, the proposed CMG can offer the advantages of achieving a consistent speed ratio and stable transmission within the entire pull‐out torque range. By using the two‐dimensional finite element method, the detailed parametric analysis and static characteristics of the proposed CMG are performed to set up its design criteria. Moreover, a quantitative comparison with a conventional CMG is conducted, and a prototype is also fabricated for experimentation to verify the validity of the proposed CMG.
Performance evaluation of secure multipath retransmission mechanism in next generation heterogeneous communication systems
Authors: Zeng Jiaxin , Cao Yuanlong , Ke Fenfen , Huang Minghe , Zhang Guanghe , Lu Wei
Published: October 2017

With the standardisation of the fifth generation (5G) wireless network interface was established in 3GPP, the features of 5G arouse great interest both in academics and industry, even government. The significant advancements of 5G wireless network technology will make a great increase in the demand for content‐rich streaming media services. What's more, many mobile devices with heterogeneous network interfaces (4G, WiFi, and even 5G) connect multiple paths for data delivery simultaneously. Multiple Transmission Control Protocol (MPTCP) is recommended by Internet Engineering Task Force (IETF) to multi‐path parallel transmission, which is an important transport layer protocol. Although there are many attractive benefits by using MPTCP for data delivery, it becomes sensitive for MPTCP to network attacks. When a subflow with the MPTCP association suffers from some network attacks (e.g. denial of service attacks), there is undoubted that it will cause large numbers of retransmission data. Unfortunately, the regular MPTCP retransmission mechanisms retransmit data over the same path, which may cause receiver buffer blocking. In this study, the authors propose effective retransmission mechanisms in MPTCP for retransmitting data on a non‐congested path. The simulation results show that the proposed retransmission mechanism has better performance than the regular’ in the network attacks.
Janus‐configured all fibre laser Doppler velocimetry
Authors: Fan Zhe , Sun Qiao , Du Lei , Bai Jie
Published: October 2017

Laser Doppler velocimetry (LDV) is a high precision instrument based on the Doppler effect of a laser, and it would greatly improve the performance of vehicle navigation and vehicle velocity metrology for its advantages. To reduce the measurement error produced by a jolt of a vehicle, a novel Janus‐configured all fibre LDV is designed. The system comprising two independent interferometers is connected by 1.55 μm single mode fibre devices. Road experiments are carried out to compare the performances of the microwave radar, single beam LDV and Janus‐configured LDV. The Janus‐configured LDV is reliable to measure the velocity of the vehicle and its root‐mean‐square error is 0.0222 m/s, while it is 0.0284 m/s for the single beam LDV. The results validate that the designed LDV can achieve improved performance of vehicle velocity measurement.
The MUSE Hubble Ultra Deep Field Survey
Authors: Inami H. , Bacon R. , Brinchmann J. , Richard J. , Contini T. , Conseil S. , Hamer S. , Akhlaghi M. , Bouché N. , Clément B. , Desprez G. , Drake A. B. , Hashimoto T. , Leclercq F. , Maseda M. , Michel-Dansac L. , Paalvast M. , Tresse L. , Ventou E. , Kollatschny W. , Boogaard L. A. , Finley H. , Marino R. A. , Schaye J. , Wisotzki L.
Published: October 2017

We have conducted a two-layered spectroscopic survey (1′ × 1′ ultra deep and 3′ × 3′ deep regions) in the Hubble Ultra Deep Field (HUDF) with the Multi Unit Spectroscopic Explorer (MUSE). The combination of a large field of view, high sensitivity, and wide wavelength coverage provides an order of magnitude improvement in spectroscopically confirmed redshifts in the HUDF; i.e., 1206 secure spectroscopic redshifts for Hubble Space Telescope (HST) continuum selected objects, which corresponds to 15% of the total (7904). The redshift distribution extends well beyond z> 3 and to HST/F775W magnitudes as faint as ≈ 30 mag (AB, 1σ). In addition, 132 secure redshifts were obtained for sources with no HST counterparts that were discovered in the MUSE data cubes by a blind search for emission-line features. In total, we present 1338 high quality redshifts, which is a factor of eight increase compared with the previously known spectroscopic redshifts in the same field. We assessed redshifts mainly with the spectral features [O ii] at z< 1.5 (473 objects) and Lyα at 2.9 <z< 6.7 (692 objects). With respect to F775W magnitude, a 50% completeness is reached at 26.5 mag for ultra deep and 25.5 mag for deep fields, and the completeness remains ≳ 20% up to 28–29 mag and ≈ 27 mag, respectively. We used the determined redshifts to test continuum color selection (dropout) diagrams of high-z galaxies. The selection condition for F336W dropouts successfully captures ≈ 80% of the targeted z ~ 2.7 galaxies. However, for higher redshift selections (F435W, F606W, and F775W dropouts), the success rates decrease to ≈ 20–40%. We empirically redefine the selection boundaries to make an attempt to improve them to ≈ 60%. The revised boundaries allow bluer colors that capture Lyα emitters with high Lyα equivalent widths falling in the broadbands used for the color-color selection. Along with this paper, we release the redshift and line flux catalog.
Multi-wavelength campaign on NGC 7469
Authors: Peretz U. , Behar E. , Kriss G. A. , Kaastra J. , Arav N. , Bianchi S. , Branduardi-Raymont G. , Cappi M. , Costantini E. , De Marco B. , Di Gesu L. , Ebrero J. , Kaspi S. , Mehdipour M. , Middei R. , Paltani S. , Petrucci P. O. , Ponti G. , Ursini F.
Published: October 2017

We have investigated the ionic column density variability of the ionized outflows associated with NGC 7469, to estimate their location and power. This could allow a better understanding of galactic feedback of AGNs to their host galaxies. Analysis of seven XMM-Newton grating observations from 2015 is reported. We used an individual-ion spectral fitting approach, and compared different epochs to accurately determine variability on timescales of years, months, and days. We find no significant column density variability in a ten-year period implying that the outflow is far from the ionizing source. The implied lower bound on the ionization equilibrium time, ten years, constrains the lower limit on the distance to be at least 12 pc, and up to 31 pc, much less but consistent with the 1 kpc wide starburst ring. The ionization distribution of column density is reconstructed from measured column densities, nicely matching results of two 2004 observations, with one large high ionization parameter (ξ) component at 2 < log ξ< 3.5, and one at 0.5 < log ξ< 1 in cgs units. The strong dependence of the expression for kinetic power, ∝ 1 /ξ, hampers tight constraints on the feedback mechanism of outflows with a large range in ionization parameter, which is often observed and indicates a non-conical outflow. The kinetic power of the outflow is estimated here to be within 0.4 and 60% of the Eddington luminosity, depending on the ion used to estimate ξ.
Motion of discrete interfaces in low-contrast random environments
Authors: Ruf Matthias
Published: October 2017

We study the asymptotic behavior of a discrete-in-time minimizing movement scheme for square lattice interfaces when both the lattice spacing and the time step vanish. The motion is assumed to be driven by minimization of a weighted random perimeter functional with an additional deterministic dissipation term. We consider rectangular initial sets and lower order random perturbations of the perimeter functional. In case of stationary,α-mixing perturbations we prove a stochastic homogenization result for the interface velocity. We also provide an example which indicates that only stationary, ergodic perturbations might not yield a spatially homogenized limit velocity for this minimizing movement scheme.
Cu-Catalyzed Cascade Annulation of Diaryliodonium Salts and Nitriles: Synthesis of Nitrogen-Containing Heterocycles
Authors: Cao Chengyao , Sheng Jinyu , Chen Chao
Published: October 2017

Developing versatile methodologies to construct various nitrogen­-containing heterocycles is a crucially significant part of contemporary organic chemistry. This review summarizes recent developments on the formation of nitrogen-containing heterocycles triggered by diaryliodonium salts. Diaryliodonium salts, as electrophilic arylating agents in the presence of catalytic copper salts, can react with nitriles to give N-arylnitrilium cations, which are highly reactive species. These species can efficiently react with nucleophiles, including C-, N- and O-nucleophiles, to give the corresponding products. This strategy is not only efficient and convenient, but also enables the synthesis of diverse nitrogen-containing heterocycles such as quinolines, quinazolines, and phenanthridines.

1 Introduction

2 Strategies and Mechanisms

3 Cascade Annulations

3.1 Cascade Annulation of Diaryliodoniums, Nitriles and C-Nucleo­philes

3.2 Cascade Annulation of Diaryliodoniums, Nitriles and N-Nucleo­philes

3.3 Cascade Annulation of Diaryliodoniums, Nitriles and O-Nucleo­philes

4 Summary and Outlook
Thieme Chemistry Journals Awardees – Where Are They Now? Bis(2-pyridyl)amides as Readily Cleavable Amides Under Catalytic, Neutral, and Room-Temperature Conditions
Authors: Kumagai Naoya , Shibasaki Masakatsu , Adachi Shinya
Published: October 2017

Mild solvolytic cleavage of bis(2-pyridyl)amide under neutral and room-temperature conditions is described. The inherently stable amide was readily activated by catalytic amounts of metal cations to react with alcohols. Based on X-ray crystallographic analysis, the primary driving force was considered to be amide distortion induced by the metal coordination of two pyridyl groups in a bidentate fashion without affecting the amide functionality. The compatibility of the acid/base-sensitive functionalities and the absence of racemization during solvolysis highlight the mildness of the present protocol.
Cyclopropane Intermediates from Insertion Reactions of
Platinum–Carbenes: A Route to Heterospiranes
Authors: Oh Chang , Kim Kiseong , Kim Soyung
Published: October 2017

Heteroaromatic-anchored enynals with a pendent alkene group were successfully cyclized through a Huisgen-type [3+2] cycloaddition to give a tetracyclic Pt–carbene complex that underwent insertion into the C–H bond in the β-position to give fused cyclopropanes that are otherwise inaccessible. On heating, the cyclopropanes smoothly rearranged to form the corresponding heterospiranes with excellent levels of stereoselectivity and high yields.
Effects of Ulnar Styloid Fractures on Unstable Distal Radius Fracture Outcomes: A Systematic Review of Comparative Studies
Authors: Almedghio Sami , Almari Fayez , Chakrabarti Indranil , Arshad Mohammed
Published: October 2017

Purpose In this literature review, functional outcomes such as Disability of Arm, Shoulder and Hand (DASH) score and the visual analog scale (VAS) of pain along with clinical outcomes such as range of movement and grip strength of treated distal radius fractures (DRF) accompanied with ulnar styloid fractures (USF) will be compared with those with isolated DRF.

Materials and Methods We analyzed articles from MEDLINE, Embase, and CINAHL that met our predetermined inclusion and exclusion criteria as per the Preferred Reporting Items for Systematic Reviews and Meta-analysis statements. This resulted in the identification of 464 articles with 18 potentially eligible studies of which 6 were included at the full-text screening stage. The primary outcomes were wrist pain, range of motion, functional outcome and satisfaction, such as VAS, and the DASH questionnaire along with radiological assessment and incidence of complications.

Results These studies involved 796 participants with DRF and 806 wrists with DRF; 444 (55%) of DRF had an associated USF. Three studies did not report any statistically significant difference in DASH scores between the DRF patients with or without USF. Two studies reported worse DASH scores in the group with associated USF. Wrist pain was reported to be statistically significantly worse in patients with associated USF in two studies. Grip strength did not exhibit a statistically significant difference in any groups in four studies. On assessing the range of motion of the wrist and forearm, only one study reported a statistically significant difference in flexion at 2 years follow-up, with less flexion in patients with USF.

Conclusion This review suggests that there is no significant correlation between a USF and the functional and clinical outcomes of DRF treatment, albeit wrist pain and less flexion were reported in some studies to be associated with USF. There is a need for more robust evidence from large randomized controlled trials to specifically look at the effects of fixation versus nonfixation of USF on DRF, or large prospective cohort studies assessing DRF with and without USF, with a minimum of 12 months follow-up.

Level of Evidence Level II—therapeutic.
Barriers to Postpartum Follow-Up and Glucose Tolerance Testing in Women with Gestational Diabetes Mellitus
Authors: Yee Lynn , Battarbee Ashley
Published: October 2017

Objective This study aims to examine factors associated with postpartum follow-up and glucose tolerance testing (GTT) in women with gestational diabetes mellitus (GDM).

Materials and Methods Case-control study of women with GDM at a single institution with available outpatient records (January 2008–February 2016). Women with pregestational diabetes mellitus were excluded. The postpartum follow-up, GTT completion, and the reason for GTT completion failure (provider vs. patient noncompliance) were assessed. Bivariable and multivariable analyses were performed to identify factors associated with postpartum follow-up and GTT completion.

Results Of 683 women, 82.0% (n = 560) returned postpartum, and 49.8% (n = 279) of those completed GTT. Women with Medicaid and late presentation to care were less likely to return (adjusted odds ratio [aOR]: 0.3, 95% confidence interval [CI]: 0.2–0.6 and aOR: 0.4, 95% CI: 0.2–0.7), but if they did, both factors were associated with increased odds of GTT completion (aOR: 2.0, 95% CI: 1.3–2.9 and aOR: 3.5, 95% CI: 1.8–6.6). Patient and provider noncompliance contributed equally to GTT completion failure. Trainee involvement was associated with improved test completion (aOR: 4.6, 95% CI: 2.4–8.8).

Conclusion The majority of women with GDM returned postpartum, but many did not receive recommended GTT. Public insurance and late presentation were associated with failure to return postpartum, but better GTT completion when a postpartum visit occurred. Trainee involvement was associated with improved adherence to screening guidelines.
Follow-up of Congenital Diaphragmatic Hernia: Need for Routinary Assessment of Acid Gastroesophageal Reflux with pH-metry
Authors: Zanini Andrea , Farris Giorgio , Morandi Anna , Festa Irene , Brisighelli Giulia , Gentilino Valerio , Leva Ernesto , Macchini Francesco
Published: October 2017

Introduction We aim to assess gastroesophageal reflux (GER) in patients treated for congenital diaphragmatic hernia (CDH) and to determine whether a pH-metry investigation should be routinely performed in follow-up.

Materials and Methods Twenty-four-hour pH-metry at 1 year was performed in all patients treated for CDH between January 2014 and April 2015 (Group 1). We compared pH-metry results to those of two other groups: children treated for esophageal atresia (EA) (Group 2) and normal babies presenting with typical symptoms (Group 3). All the pH-metric findings were analyzed and compared. Intra-group analysis was performed in Group 1.

Results Group 1 consisted of 21, Group 2 of 24, and Group 3 of 21 patients. Mean pH-metry values for Groups 1, 2, and 3 were, respectively: reflux index (RI) 4.3, 5.1, and 3.9; total number of refluxes (NR) 79.5, 88.8, and 88.7; refluxes longer than 5′ (R > 5) 1.7, 2.3, and 1.47; and longest reflux episode (LR) 11.4, 13.3, and 8.6. No significant differences were found between Group 1 and the others. Only two CDH patients presented with GER-related symptoms. Patch was associated with significantly higher RI (8.5 vs. 2.98, p = 0.03). The worse was the defect, the worse were the pH-metric results (RI: A3.09, B3.15, and C9.1).

Conclusion We believe that a routine GER assessment should be performed in all CDH patients regardless the presence of symptoms.

Level of Evidence This is a Level II study.