bluuebunny/crossref_metadata_2025 huggingface dataset:
Feasibility and anticipated acceptability of community health worker-facilitated HPV self-sampling for cervical cancer screening around Lake County, Indiana
Authors: Adekunle Tiwaladeoluwa B. , Arreola Alyssa , Sembian Sathveka , Castro Raquel , Claure Layla , Balian Lara , Rodriguez Natalia M.
Published: June 2023

Background/Objective:

In light of calls to engage community health workers (CHWs) in the delivery of cervical cancer screening innovations, this study explores CHW perspectives on i) barriers to cervical cancer screening in a predominantly Hispanic community in Lake County, Indiana, the county with the highest cervical mortality in the state; and ii) the acceptability and feasibility of CHW-facilitated human papillomavirus (HPV) self-sampling as a means of reducing screening disparities.

Methods:

In 2021, in-depth interviews were conducted with 15 CHWs employed by Lake County community-based organizations including clinics, schools, and faith-based organizations.

Results:

Harnessing CHWs’ voices as insiders with knowledge of their communities’ health landscape, our analysis identified multilevel barriers to screening that spanned individual, interpersonal, and community levels of the socio-ecological model. CHW-facilitated HPV self-sampling shows promise of mitigating several barriers to cervical cancer screening. Privacy, time saved, and comfort were perceived to be facilitators for acceptability, with concerns about the novelty of this approach and trust in provider (as opposed to CHW) expertise emerging as key barriers. In terms of feasibility, synergies with existing CHW work, and some community members' prior experience with self-sampling were found to be facilitators, while CHW’s time limitations and self-efficacy in providing adequate medical support were areas of concern. Considerations for adoption included CHW training, gender concordance, safety, and respect, among others.

Conclusion:

This study provides critical insights from CHWs as key stakeholders on a screening model that directly engages them, which can inform implementation to increase screening in medically-underserved communities in the US.
Introduction: Power to the image! Science, technology and visual diplomacy
Authors: Turchetti Simone , Adamson Matthew
Published: June 2023

This special issue explores the power that images with a techno-scientific content can have in international relations. As we introduce the articles in the collection, we highlight how the study of this influence extends current research in the separate (but increasingly interacting) domains of history of science and technology, and political science. We then show how images of different types (photographs, cartoons and plots) can inform inter-state transactions through their public appeal alongside the better-studied dialogic practices of the diplomatic arena. Finally, we offer an analysis of the interlacing of different diplomatic tracks based on words and images and conclude that, in contrast with words, images conflate agency and argument, therefore creating opportunities to inform transactions and negotiations which their designers may not have even intended.
Effect of monochromatic light on light adaptation and opsin expression in Ectropis grisescens
Authors: Shan Yao , Xu Manfei , Tan Chang , Chen Zongmao , Wang Guochang , Bian Lei
Published: June 2023

Light has a substantial effect on the behaviour and physiology of nocturnal moths. Ectropis grisescens is a major nocturnal tea pest in China, and light traps are commonly used to control geometrid moths because of their positive phototaxis. However, some moths gather around light traps and enter the light adaptation state, which decreases the efficacy of light traps in controlling this pest. We identified opsin genes and the spectral sensitivities of the photoreceptors of E. grisescens moths. We also determined the effects of several monochromatic lights on opsin gene expression and light adaptation. We detected three types of opsin genes and six spectral sensitive peaks (at 370, 390, 480, 530, 550, and 580 nm). We also observed significant changes in the diurnal rhythm of opsin gene expression under different light conditions. When active males were suddenly exposed to different monochromatic lights, they quickly entered the light adaptation state, and the adaptation time was negatively correlated with the light intensity. Males were most sensitive to 390 nm wavelengths, followed by 544 nm, 457 nm, and 593 nm. Red light (627 nm) did not affect the activity of E. grisescens males but had detectable physiological effects.
The articulatory properties of apical vowels in Hefei Mandarin
Authors: Kong Huifang , Wu Shengyi , Li Mingxing , Shen Xiangrong
Published: June 2023

Apical vowels are widely observed across Chinese dialects, such as the rime of [sɹ̩55] ‘think’ in Mandarin Chinese, which is a syllabic approximant homorganic to its preceding sibilant. The apical vowels in Hefei Mandarin differ from those in Mandarin Chinese and most other languages in three aspects: (i) there are three phonetic apical vowels [ɹ̩], [ɹ̩ʷ], and [ɻ̩] while others usually have one or two, (ii) the alveolar apical [ɹ̩] appears after both homorganic and non-homorganic consonants, e.g. [sɹ̩] vs. [pɹ̩], and (iii) there is a phonological contrast between an unrounded apical [ɹ̩] and a rounded apical [ɹ̩ʷ], e.g. [sɹ̩] vs. [sɹ̩ʷ]. The articulatory properties of the three apical vowels were examined in this study using ultrasound techniques and the results revealed that: (i) the commonalities of tongue gestures for the apical vowels include a retracted tongue root, a lowered tongue dorsum or blade, or both, together with a coronal constriction implemented with the blade and/or the tip; (ii) lip gestures are involved in distinguishing the three apical segments; (iii) the three segments each have its distinct articulatory gestures within a speaker that cannot be simply attributed to the influence from their preceding consonants, with [ɹ̩] and [ɹ̩ʷ] involving a grooving in the front part of the tongue and [ɻ̩] involving a retraction of tongue body in the back region of the vocal tract; (iv) the articulatory gesture of [ɹ̩] after a homorganic consonant, e.g. in [sɹ̩], is similar to that after a non-homorganic consonant, e.g. in [pɹ̩], suggesting an independent articulatory target for this segment.
Giant cardiac cavernous haemangioma of the right atrium in a newborn successfully managed using combined therapy
Authors: Zhanatkyzy Aikerim , Gorbunov Dmitry , Ivanova-Razumova Tatiana , Baigalkanova Almira , Manabay Aizhan
Published: June 2023

Cardiac tumours are extremely rare. Most of the cases are diagnosed post-mortem.

In this case, a tumour was found in a neonate during routine ultrasound screening in the first trimester of pregnancy. After birth, resection of the formation was performed and histologically confirmed as a cavernous haemangioma. Additionally, propranolol was prescribed in order to prevent relapse.
ON THE SAFE STORAGE OF BAGASSE
Authors: MITCHELL S. L. , MYERS T. G.
Published: June 2023

In this paper, we investigate the thermal evolution in a one-dimensional bagasse stockpile. The mathematical model involves four unknowns: the temperature, oxygen content, liquid water content and water vapour content. We first nondimensionalize the model to identify dominant terms and so simplify the system. We then calculate solutions for the approximate and full system. It is shown that under certain conditions spontaneous combustion will occur. Most importantly, we show that spontaneous combustion can be avoided by sequential building. To be specific, in a situation where, say, a$4.7\,$m stockpile can spontaneously combust, we could construct a$3\,$m pile and then some days later add another$1.7\,$m to produce a stable$4.7\,$m pile.
CONDITIONAL FLATNESS, FIBERWISE LOCALIZATIONS, AND ADMISSIBLE REFLECTIONS
Authors: GRAN MARINO , SCHERER JÉRÔME
Published: June 2023

We extend the group-theoretic notion of conditional flatness for a localization functor to any pointed category, and investigate it in the context of homological categories and of semi-abelian categories. In the presence of functorial fiberwise localization, analogous results to those obtained in the category of groups hold, and we provide existence theorems for certain localization functors in specific semi-abelian categories. We prove that a Birkhoff subcategory of an ideal determined category yields a conditionally flat localization, and explain how conditional flatness corresponds to the property of admissibility of an adjunction from the point of view of categorical Galois theory. Under the assumption of fiberwise localization, we give a simple criterion to determine when a (normal epi)-reflection is a torsion-free reflection. This is shown to apply, in particular, to nullification functors in any semi-abelian variety of universal algebras. We also relate semi-left-exactness for a localization functor L with what is called right properness for the L-local model structure.
Changes in Tropical Cyclone Disasters Over China During 2001–2020
Authors: Li Ying , Zhao Shanshan , Zhao Dajun , Gao Ge , Xu Hongxiong , Jiang Yundi
Published: June 2023

Tropical cyclones (TCs) constitute one of the major types of meteorological disasters in China, causing extensive damage. Based on the latest quality‐controlled provincial‐level TC disaster losses data over China from 2001 to 2020, the spatiotemporal variation in TC disaster and its link with TC activity in the form of prevailing track, precipitation, and intensity were investigated. Results showed that the areas impacted by TCs expanded significantly in the past decade (2011–2020) compared with the previous decade (2001–2010) throughout China, while the direct economic losses resulting from TCs did not increase significantly. Regionally, TC disaster losses increased in Northeast China but decreased in Fujian province. Causal analysis indicated that the increased influential TC (ITC) frequency and TC precipitation together led to the increase in damage for northern China. Also, more westward ITCs resulted in the increase in TC disasters for southwestern China. For southeastern China, the reduction in TC disasters was related to the northward shift in the northwestward ITC track. Although TC disasters increase with exposure, they are heavily influenced by TC track, precipitation, and intensity. Our findings suggest that more attention should be paid to TC prediction and early warning in northern China, especially Northeast China, where TC disasters are growing but there is greater vulnerability and insufficient capacity for TC prevention and mitigation.
Clear Air Turbulence Resolved by Numerical Weather Prediction Model Validated by Onboard and Virtual Flight Data
Authors: Yoshimura R. , Ito J. , Schittenhelm P. A. , Suzuki K. , Yakeno A. , Obayashi S.
Published: June 2023

A clear air turbulence (CAT) occurred on 30 December 2020 over Tokyo, Japan. The CAT was largely generated by breaking Kelvin‐Helmholtz (KH) instability waves in the free atmosphere. A regional numerical weather prediction model simulated the event with fine resolution (35 m). Onboard‐recorded flight data and a flight simulation were utilized to validate the meteorological simulation. The locations of the reproduced strong turbulence agree well with the regions where flights encountered turbulence on that day. In a simulation with the finest resolution, the KH waves and their breaking were resolved. When the resolution was finer, the turbulent eddies were stronger, causing meteorological effects on the airplanes. The response of a virtual airplane to the simulated turbulence was estimated using a flight simulation. By comparing onboard‐recorded data with virtual flight data, we confirm that turbulent eddies are reasonably reproduced.
Global Crustal Thickness Revealed by Surface Waves Orbiting Mars
Authors: Kim D. , Duran C. , Giardini D. , Plesa A.‐C. , Stähler S. C. , Boehm C. , Lekić V. , McLennan S. M. , Ceylan S. , Clinton J. F. , Davis P. , Khan A. , Knapmeyer‐Endrun B. , Panning M. P. , Wieczorek M. , Lognonné P. , Banerdt W. B.
Published: June 2023

We report observations of Rayleigh waves that orbit around Mars up to three times following the S1222a marsquake. Averaging these signals, we find the largest amplitude signals at 30 and 85 s central period, propagating with distinctly different group velocities of 2.9 and 3.8 km/s, respectively. The group velocities constraining the average crustal thickness beneath the great circle path rule out the majority of previous crustal models of Mars that have a >200 kg/m3 density contrast across the equatorial dichotomy between northern lowlands and southern highlands. We find that the thickness of the Martian crust is 42–56 km on average, and thus thicker than the crusts of the Earth and Moon. Considered with the context of thermal evolution models, a thick Martian crust suggests that the crust must contain 50%–70% of the total heat production to explain present‐day local melt zones in the interior of Mars.
Variation of the Jovian Magnetopause Under Constant Solar Wind Conditions: Significance of Magnetodisc Dynamics
Authors: Feng Enhao , Zhang Binzheng , Yao Zhonghua , Delamere Peter A. , Zheng Zhiqi , Dunn William R. , Ye Sheng‐Yi
Published: June 2023

It is generally believed that variations in the upstream solar wind (SW) and interplanetary magnetic field (IMF) conditions are the main cause of changes of Jupiter's magnetopause (JM) location. However, most previous pressure balance models for the JM are axisymmetric and do not consider internal drivers, for example, the dynamics of the magnetodisc. We use three‐dimensional global magnetosphere simulations to investigate the variation of the JM under constant SW/IMF conditions. These simulations show that even without variations in the upstream driving conditions, the JM can exhibit dynamic variations, suggesting a range as large as 50 Jupiter radii in the subsolar location. Our study shows that the interchange structures in the Jovian magnetodisc will introduce significant radial dynamic pressure, which can drive significant variation in the JM location. The results provide important new context for interpreting the JM location and dynamics, with key implications for other internally mass‐loaded and/or rapidly rotating systems.
Tidally Modulated Glacial Seismicity at the Foundation Ice Stream, West Antarctica
Authors: Lucas Erica M. , Nyblade Andrew A. , Aster Richard C. , Wiens Douglas A. , Wilson Terry J. , Winberry J. Paul , Huerta Audrey D.
Published: June 2023

We investigate the occurrence of repeating glacial seismicity near the grounding line of the Foundation Ice Stream and further upstream using continuous broadband seismic data collected by Polar Earth Observing Network (POLENET/A‐NET) stations from 2014 through 2019. Through manual identification and cross‐correlation analysis, 2,237 discrete icequakes (1.5  ML  2.6) are detected in two spatial clusters, one located at the grounding line of the Foundation Ice Stream (2,219 event detections) and a second located further upstream proximal to a subglacial ridge (18 event detections). Seismicity is predominantly concentrated in the Schmidt Hills, located adjacent to the grounding line of the Foundation Ice Stream, and shows clear ocean tide modulation. Seismic events primarily occur during spring tides, and, on a shorter timescale, concurrent with the rising tide preceding daily maximum high tide. The seismicity can be attributed to stick‐slip motion and fracturing that preferentially occur during rising tides. Seismicity located further upstream in the southern portion of the Foundation Ice Stream most likely reflects basal stick‐slip processes associated with the subglacial topographic high.
Spatio‐Temporal Coarse‐Graining Decomposition of the Global Ocean Geostrophic Kinetic Energy
Authors: Buzzicotti M. , Storer B. A. , Khatri H. , Griffies S. M. , Aluie H.
Published: June 2023

We expand on a recent determination of the first global energy spectrum of the ocean's surface geostrophic circulation (Storer et al., 2022, https://doi.org/10.1038/s41467-022-33031-3) using a coarse‐graining (CG) method. We compare spectra from CG to those from spherical harmonics by treating land in a manner consistent with the boundary conditions. While the two methods yield qualitatively consistent domain‐averaged results, spherical harmonics spectra are too noisy at gyre‐scales (>1,000 km). More importantly, spherical harmonics are inherently global and cannot provide local information connecting scales with currents geographically. CG shows that the extra‐tropics mesoscales (100–500 km) have a root‐mean‐square (rms) velocity of ∼15 cm/s, which increases to ∼30–40 cm/s locally in the Gulf Stream and Kuroshio and to ∼16–28 cm/s in the ACC. There is notable hemispheric asymmetry in mesoscale energy‐per‐area, which is higher in the north due to continental boundaries. We estimate that ≈25%–50% of total geostrophic energy is at scales smaller than 100 km, and is un(der)‐resolved by pre‐SWOT satellite products. Spectra of the time‐mean circulation show that most of its energy (up to 70%) resides in stationary eddies with characteristic scales smaller than (<500 km). This highlights the preponderance of “standing” small‐scale structures in the global ocean due to the temporally coherent forcing by boundaries. By coarse‐graining in space and time, we compute the first spatio‐temporal global spectrum of geostrophic circulation from AVISO and NEMO. These spectra show that every length‐scale evolves over a wide range of time‐scales with a consistent peak at ≈200 km and ≈2–3 weeks.
Widespread Bradyrhizobium distribution of diverse Type III effectors that trigger legume nodulation in the absence of Nod factor
Authors: Camuel Alicia , Teulet Albin , Carcagno Mélanie , Haq Fazal , Pacquit Valérie , Gully Djamel , Pervent Marjorie , Chaintreuil Clémence , Fardoux Joël , Horta-Araujo Natasha , Okazaki Shin , Ratu Safirah Tasa Nerves , Gueye Fatou , Zilli Jerri , Nouwen Nico , Arrighi Jean-François , Luo Haiwei , Mergaert Peter , Deslandes Laurent , Giraud Eric
Published: June 2023

The establishment of the rhizobium-legume symbiosis is generally based on plant perception of Nod factors (NFs) synthesized by the bacteria. However, some Bradyrhizobium strains can nodulate certain legume species, such as Aeschynomene spp. or Glycine max, independently of NFs, and via two different processes that are distinguished by the necessity or not of a type III secretion system (T3SS). ErnA is the first known type III effector (T3E) triggering nodulation in Aeschynomene indica. In this study, a collection of 196 sequenced Bradyrhizobium strains was tested on A. indica. Only strains belonging to the photosynthetic supergroup can develop a NF-T3SS-independent symbiosis, while the ability to use a T3SS-dependent process is found in multiple supergroups. Of these, 14 strains lacking ernA were tested by mutagenesis to identify new T3Es triggering nodulation. We discovered a novel T3E, Sup3, a putative SUMO-protease without similarity to ErnA. Its mutation in Bradyrhizobium strains NAS96.2 and WSM1744 abolishes nodulation and its introduction in an ernA mutant of strain ORS3257 restores nodulation. Moreover, ectopic expression of sup3 in A. indica roots led to the formation of spontaneous nodules. We also report three other new T3Es, Ubi1, Ubi2 and Ubi3, which each contribute to the nodulation capacity of strain LMTR13. These T3Es have no homology to known proteins but share with ErnA three motifs necessary for ErnA activity. Together, our results highlight an unsuspected distribution and diversity of T3Es within the Bradyrhizobium genus that may contribute to their symbiotic efficiency by participating in triggering legume nodulation.
A family of oxychloride amorphous solid electrolytes for long-cycling all-solid-state lithium batteries
Authors: Zhang Shumin , Zhao Feipeng , Chen Jiatang , Fu Jiamin , Luo Jing , Alahakoon Sandamini H. , Chang Lo-Yueh , Feng Renfei , Shakouri Mohsen , Liang Jianwen , Zhao Yang , Li Xiaona , He Le , Huang Yining , Sham Tsun-Kong , Sun Xueliang
Published: June 2023

Solid electrolyte is vital to ensure all-solid-state batteries with improved safety, long cyclability, and feasibility at different temperatures. Herein, we report a new family of amorphous solid electrolytes, xLi2O-MCly (M = Ta or Hf, 0.8 ≤ x ≤ 2, y = 5 or 4). xLi2O-MCly amorphous solid electrolytes can achieve desirable ionic conductivities up to 6.6 × 10−3 S cm−1 at 25 °C, which is one of the highest values among all the reported amorphous solid electrolytes and comparable to those of the popular crystalline ones. The mixed-anion structural models of xLi2O-MCly amorphous SEs are well established and correlated to the ionic conductivities. It is found that the oxygen-jointed anion networks with abundant terminal chlorines in xLi2O-MCly amorphous solid electrolytes play an important role for the fast Li-ion conduction. More importantly, all-solid-state batteries using the amorphous solid electrolytes show excellent electrochemical performance at both 25 °C and −10 °C. Long cycle life (more than 2400 times of charging and discharging) can be achieved for all-solid-state batteries using the xLi2O-TaCl5 amorphous solid electrolyte at 400 mA g−1, demonstrating vast application prospects of the oxychloride amorphous solid electrolytes.
Temperature-dependent rearrangement of gas molecules in ultramicroporous materials for tunable adsorption of CO2 and C2H2
Authors: Zhang Zhaoqiang , Chen Yinlin , Chai Kungang , Kang Chengjun , Peh Shing Bo , Li He , Ren Junyu , Shi Xiansong , Han Xue , Dejoie Catherine , Day Sarah J. , Yang Sihai , Zhao Dan
Published: June 2023

The interactions between adsorbed gas molecules within porous metal-organic frameworks are crucial to gas selectivity but remain poorly explored. Here, we report the modulation of packing geometries of CO2and C2H2clusters within the ultramicroporous CUK-1 material as a function of temperature. In-situ synchrotron X-ray diffraction reveals a unique temperature-dependent reversal of CO2and C2H2adsorption affinities on CUK-1, which is validated by gas sorption and dynamic breakthrough experiments, affording high-purity C2H2(99.95%) from the equimolar mixture of C2H2/CO2via a one-step purification process. At low temperatures (<253 K), CUK-1 preferentially adsorbs CO2with both high selectivity (>10) and capacity (170 cm3g−1) owing to the formation of CO2tetramers that simultaneously maximize the guest-guest and host-guest interactions. At room temperature, conventionally selective adsorption of C2H2is observed. The selectivity reversal, structural robustness, and facile regeneration of CUK-1 suggest its potential for producing high-purity C2H2by temperature-swing sorption.
Determining spin-orbit coupling in graphene by quasiparticle interference imaging
Authors: Sun Lihuan , Rademaker Louk , Mauro Diego , Scarfato Alessandro , Pásztor Árpád , Gutiérrez-Lezama Ignacio , Wang Zhe , Martinez-Castro Jose , Morpurgo Alberto F. , Renner Christoph
Published: June 2023

Inducing and controlling spin-orbit coupling (SOC) in graphene is key to create topological states of matter, and for the realization of spintronic devices. Placing graphene onto a transition metal dichalcogenide is currently the most successful strategy to achieve this goal, but there is no consensus as to the nature and the magnitude of the induced SOC. Here, we show that the presence of backscattering in graphene-on-WSe2 heterostructures can be used to probe SOC and to determine its strength quantitatively, by imaging quasiparticle interference with a scanning tunneling microscope. A detailed theoretical analysis of the Fourier transform of quasiparticle interference images reveals that the induced SOC consists of a valley-Zeeman (λvZ ≈ 2 meV) and a Rashba (λR ≈ 15 meV) term, one order of magnitude larger than what theory predicts, but in excellent agreement with earlier transport experiments. The validity of our analysis is confirmed by measurements on a 30 degree twist angle heterostructure that exhibits no backscattering, as expected from symmetry considerations. Our results demonstrate a viable strategy to determine SOC quantitatively by imaging quasiparticle interference.
Halide-assisted differential growth of chiral nanoparticles with threefold rotational symmetry
Authors: Zheng Jiapeng , Boukouvala Christina , Lewis George R. , Ma Yicong , Chen Yang , Ringe Emilie , Shao Lei , Huang Zhifeng , Wang Jianfang
Published: June 2023

Enriching the library of chiral plasmonic nanoparticles that can be chemically mass-produced will greatly facilitate the applications of chiral plasmonics in areas ranging from constructing optical metamaterials to sensing chiral molecules and activating immune cells. Here we report on a halide-assisted differential growth strategy that can direct the anisotropic growth of chiral Au nanoparticles with tunable sizes and diverse morphologies. Anisotropic Au nanodisks are employed as seeds to yield triskelion-shaped chiral nanoparticles with threefold rotational symmetry and high dissymmetry factors. The averaged scattering g-factors of the l- and d-nanotriskelions are as large as 0.57 and − 0.49 at 650 nm, respectively. The Au nanotriskelions have been applied in chiral optical switching devices and chiral nanoemitters. We also demonstrate that the manipulation of the directional growth rate enables the generation of a variety of chiral morphologies in the presence of homochiral ligands.
Embedding oxophilic rare-earth single atom in platinum nanoclusters for efficient hydrogen electro-oxidation
Authors: Wang Xiaoning , Tong Yanfu , Feng Wenting , Liu Pengyun , Li Xuejin , Cui Yongpeng , Cai Tonghui , Zhao Lianming , Xue Qingzhong , Yan Zifeng , Yuan Xun , Xing Wei
Published: June 2023

Designing Pt-based electrocatalysts with high catalytic activity and CO tolerance is challenging but extremely desirable for alkaline hydrogen oxidation reaction. Herein we report the design of a series of single-atom lanthanide (La, Ce, Pr, Nd, and Lu)-embedded ultrasmall Pt nanoclusters for efficient alkaline hydrogen electro-oxidation catalysis based on vapor filling and spatially confined reduction/growth of metal species. Mechanism studies reveal that oxophilic single-atom lanthanide species in Pt nanoclusters can serve as the Lewis acid site for selective OH-adsorption and regulate the binding strength of intermediates on Pt sites, which promotes the kinetics of hydrogen oxidation and CO oxidation by accelerating the combination of OH−and *H/*CO in kinetics and thermodynamics, endowing the electrocatalyst with up to 14.3-times higher mass activity than commercial Pt/C and enhanced CO tolerance. This work may shed light on the design of metal nanocluster-based electrocatalysts for energy conversion.
Altering the spectroscopy, electronic structure, and bonding of organometallic curium(III) upon coordination of 4,4′−bipyridine
Authors: Long Brian N. , Beltrán-Leíva María J. , Sperling Joseph M. , Poe Todd N. , Celis-Barros Cristian , Albrecht-Schönzart Thomas E.
Published: June 2023

Structural and electronic characterization of (Cp′3Cm)2(μ−4,4′−bpy) (Cp′ = trimethylsilylcyclopentadienyl, 4,4′−bpy = 4,4′−bipyridine) is reported and provides a rare example of curium−carbon bonding. Cp′3Cm displays unexpectedly low energy emission that is quenched upon coordination by 4,4′−bipyridine. Electronic structure calculations on Cp′3Cm and (Cp′3Cm)2(μ−4,4′−bpy) rule out significant differences in the emissive state, rendering 4,4′−bipyridine as the primary quenching agent. Comparisons of (Cp′3Cm)2(μ−4,4′−bpy) with its samarium and gadolinium analogues reveal atypical bonding patterns and electronic features that offer insights into bonding between carbon with f-block metal ions. Here we show the structural characterization of a curium−carbon bond, in addition to the unique electronic properties never before observed in a curium compound.
Offshore freshened groundwater in the Pearl River estuary and shelf as a significant water resource
Authors: Sheng Chong , Jiao Jiu Jimmy , Luo Xin , Zuo Jinchao , Jia Lei , Cao Jinghe
Published: June 2023

Large-river deltaic estuaries and adjacent continental shelves have experienced multiple phases of transgressions and regressions to form interlayered aquifer-aquitard systems and are expected to host vast paleo-terrestrial groundwater hundreds of kilometres offshore. Here, we used offshore hydrogeology, marine geophysical reflections, porewater geochemistry, and paleo-hydrogeological models, and identified a previously unknown offshore freshened groundwater body with a static volume up to 575.6 ± 44.9 km3 in the Pearl River Estuary and adjacent continental shelf, with the freshwater extending as far as 55 km offshore. An integrated analysis of stable isotopic compositions and water quality indices reveals the meteoric origins of such freshened groundwater and its significance as potential potable water or raw water source for desalination. Hotspots of offshore freshened groundwater in large-river deltaic estuaries and adjacent continental shelves, likely a global phenomenon, have a great potential for exploitable water resources in highly urbanized coastal areas suffering from freshwater shortage.
Coherent heteroepitaxial growth of I-III-VI2 Ag(In,Ga)S2 colloidal nanocrystals with near-unity quantum yield for use in luminescent solar concentrators
Authors: Lee Hak June , Im Seongbin , Jung Dongju , Kim Kyuri , Chae Jong Ah , Lim Jaemin , Park Jeong Woo , Shin Doyoon , Char Kookheon , Jeong Byeong Guk , Park Ji-Sang , Hwang Euyheon , Lee Doh C. , Park Young-Shin , Song Hyung-Jun , Chang Jun Hyuk , Bae Wan Ki
Published: June 2023

Colloidal Ag(In,Ga)S2 nanocrystals (AIGS NCs) with the band gap tunability by their size and composition within visible range have garnered surging interest. High absorption cross-section and narrow emission linewidth of AIGS NCs make them ideally suited to address the challenges of Cd-free NCs in wide-ranging photonic applications. However, AIGS NCs have shown relatively underwhelming photoluminescence quantum yield (PL QY) to date, primarily because coherent heteroepitaxy has not been realized. Here, we report the heteroepitaxy for AIGS-AgGaS2 (AIGS-AGS) core-shell NCs bearing near-unity PL QYs in almost full visible range (460 to 620 nm) and enhanced photochemical stability. Key to the successful growth of AIGS-AGS NCs is the use of the Ag-S-Ga(OA)2 complex, which complements the reactivities among cations for both homogeneous AIGS cores in various compositions and uniform AGS shell growth. The heteroepitaxy between AIGS and AGS results in the Type I heterojunction that effectively confines charge carriers within the emissive core without optically active interfacial defects. AIGS-AGS NCs show higher extinction coefficient and narrower spectral linewidth compared to state-of-the-art heavy metal-free NCs, prompting their immediate use in practicable applications including displays and luminescent solar concentrators (LSCs).
Ultracompact single-nanowire-morphed grippers driven by vectorial Lorentz forces for dexterous robotic manipulations
Authors: Yan Jiang , Zhang Ying , Liu Zongguang , Wang Junzhuan , Xu Jun , Yu Linwei
Published: June 2023

Ultracompact and soft pairwise grippers, capable of swift large-amplitude multi-dimensional maneuvering, are widely needed for high-precision manipulation, assembly and treatment of microscale objects. In this work, we demonstrate the simplest construction of such robotic structures, shaped via a single-nanowire-morphing and powered by geometry-tailored Lorentz vectorial forces. This has been accomplished via a designable folding growth of ultralong and ultrathin silicon NWs into single and nested omega-ring structures, which can then be suspended upon electrode frames and coated with silver metal layer to carry a passing current along geometry-tailored pathway. Within a magnetic field, the grippers can be driven by the Lorentz forces to demonstrate swift large-amplitude maneuvers of grasping, flapping and twisting of microscale objects, as well as high-frequency or even resonant vibrations to overcome sticky van de Waals forces in microscale for a reliable releasing of carried payloads. More sophisticated and functional teamwork of mutual alignment, precise passing and selective light-emitting-diode unit testing and installation were also successfully accomplished via pairwise gripper collaborations. This single-nanowire-morphing strategy provides an ideal platform to rapidly design, construct and prototype a wide range of advanced ultracompact nanorobotic, mechanical sensing and biological manipulation functionalities.
Interaction between tissue-dwelling helminth and the gut microbiota drives mucosal immunoregulation
Authors: Wang Yugui , Guo Aijiang , Zou Yang , Mu Wenjie , Zhang Shengying , Shi Zhiqi , Liu Zhongli , Cai Xuepeng , Zhu Xing-Quan , Wang Shuai
Published: June 2023

Tissue-dwelling helminths affect billions of people around the world. They are potent manipulators of the host immune system, prominently by promoting regulatory T cells (Tregs) and are generally associated with a modified host gut microbiome. However, the role of the gut microbiota in the immunomodulatory processes for these non-intestinal parasites is still unclear. In the present study, we used an extra-intestinal cestode helminth model-larval Echinococcus multilocularis to explore the tripartite partnership (host-helminth-bacteria) in the context of regulating colonic Tregs in Balb/c mice. We showed that larval E. multilocularis infection in the peritoneal cavity attenuated colitis in Balb/c mice and induced a significant expansion of colonic Foxp3+ Treg populations. Fecal microbiota depletion and transplantation experiments showed that the gut microbiota contributed to increasing Tregs after the helminth infection. Shotgun metagenomic and metabolic analyses revealed that the gut microbiome structure after infection was significantly shifted with a remarkable increase of Lactobacillus reuteri and that the microbial metabolic capability was reprogrammed to produce more Treg cell regulator-short-chain fatty acids in feces. Furthermore, we also prove that the L. reuteri strain elevated in infected mice was sufficient to promote the colonic Treg frequency and its growth was potentially associated with T cell-dependent immunity in larval E. multilocularis infection. Collectively, these findings indicate that the extraintestinal helminth drives expansions of host colonic Tregs through the gut microbes. This study suggests that the gut microbiome serves as a critical component of anti-inflammation effects even for a therapy based on an extraintestinal helminth.
Accelerating materials-space exploration for thermal insulators by mapping materials properties via artificial intelligence
Authors: Purcell Thomas A. R. , Scheffler Matthias , Ghiringhelli Luca M. , Carbogno Christian
Published: June 2023

Reliable artificial-intelligence models have the potential to accelerate the discovery of materials with optimal properties for various applications, including superconductivity, catalysis, and thermoelectricity. Advancements in this field are often hindered by the scarcity and quality of available data and the significant effort required to acquire new data. For such applications, reliable surrogate models that help guide materials space exploration using easily accessible materials properties are urgently needed. Here, we present a general, data-driven framework that provides quantitative predictions as well as qualitative rules for steering data creation for all datasets via a combination of symbolic regression and sensitivity analysis. We demonstrate the power of the framework by generating an accurate analytic model for the lattice thermal conductivity using only 75 experimentally measured values. By extracting the most influential material properties from this model, we are then able to hierarchically screen 732 materials and find 80 ultra-insulating materials.
Investigating genomic medicine practice and perceptions amongst Australian non-genetics physicians to inform education and implementation
Authors: Nisselle Amy , King Emily , Terrill Bronwyn , Davey Belinda , McClaren Belinda , Dunlop Kate , Graves Debra , Metcalfe Sylvia , Gaff Clara
Published: June 2023

Genomic medicine is being implemented on a global scale, requiring a genomic-competent health workforce. To inform education as part of implementation strategies to optimize adoption of genomics by non-genetics physicians, we investigated current practices, perceptions and preferences relating to genomic testing and education. Australian non-genetics physicians completed an online survey; we conducted univariate and multivariate analyses of determinants of confidence and engagement with genomic medicine. Confident or engaged respondents were more likely to be pediatricians, have completed continuing genomics education (CGE) and/or have genomics research experience. Confident or engaged respondents were also more likely to prefer to request genomic testing with support from genetics services than other models. Respondents who had completed CGE and were engaged reported higher confidence than those who were not engaged. We propose a progression of genomic competence aligned with service delivery models, where education is one enabler of mastery or independence to facilitate genomic tests (from referral to requesting with or without clinical genetics support). Workplace learning could provide additional impetus for adoption.
To restrict or not to restrict? Practical considerations for optimizing dietary protein interactions on levodopa absorption in Parkinson’s disease
Authors: Rusch C. , Flanagan R. , Suh H. , Subramanian I.
Published: June 2023

Administration of levodopa for Parkinson’s disease (PD) has remained the most effective therapy for symptom management despite being in use for over 50 years. Advancing disease and age, changing tolerability and gastrointestinal (GI) dysfunction may result in change in dietary habits and body weight, as well as unpredictable motor fluctuations and dyskinesias. Dietary proteins which convert into amino acids after digestion are implicated as major factors that inhibit levodopa absorption. For people living with PD (PwP) who experience motor fluctuations, low protein diets (LPD) and protein redistribution diets (PRD) may be effective and are often recommended as a non-pharmacologic approach for improving levodopa bioavailability. However, there is a lack of consensus on a standard definition of these diets and appropriate treatment algorithms for usage. This may be due to the paucity of high-level evidence of LPD and PRD in PwP and whether all or specific subgroups of patients would benefit from these strategies. Managing diet and protein intake with proper education and monitoring may reduce complications associated with these diets such as dyskinesias and unintentional weight loss. Additionally, alterations to medications and GI function may alter levodopa pharmacokinetics. In this narrative review we focus on 1) mechanisms of dietary protein and levodopa absorption in the intestine and blood brain barrier, 2) dietetic approaches to manage protein and levodopa interactions and 3) practical issues for treating PwP as well as future directions to be considered.
Biodiversity of Philippine marine fishes: A DNA barcode reference library based on voucher specimens
Authors: Bemis Katherine E. , Girard Matthew G. , Santos Mudjekeewis D. , Carpenter Kent E. , Deeds Jonathan R. , Pitassy Diane E. , Flores Nicko Amor L. , Hunter Elizabeth S. , Driskell Amy C. , Macdonald Kenneth S. , Weigt Lee A. , Williams Jeffrey T.
Published: June 2023

Accurate identification of fishes is essential for understanding their biology and to ensure food safety for consumers. DNA barcoding is an important tool because it can verify identifications of both whole and processed fishes that have had key morphological characters removed (e.g., filets, fish meal); however, DNA reference libraries are incomplete, and public repositories for sequence data contain incorrectly identified sequences. During a nine-year sampling program in the Philippines, a global biodiversity hotspot for marine fishes, we developed a verified reference library of cytochrome c oxidase subunit I (COI) sequences for 2,525 specimens representing 984 species. Specimens were primarily purchased from markets, with additional diversity collected using rotenone or fishing gear. Species identifications were verified based on taxonomic, phenotypic, and genotypic data, and sequences are associated with voucher specimens, live-color photographs, and genetic samples catalogued at Smithsonian Institution, National Museum of Natural History. The Biodiversity of Philippine Marine Fishes dataset is released herein to increase knowledge of species diversity and distributions and to facilitate accurate identification of market fishes.
Global climatological data of ocean thermohaline parameters derived from WOA18
Authors: Chu Peter C. , Fan Chenwu
Published: June 2023

This is a global ocean climatological dataset of 17 thermohaline parameters such as isothermal layer (ITL) depth (hT), mixed layer (ML) depth (hD), thermocline gradient (GT), pycnocline gradient (GD) determined from temperature (T) and salinity (S) profiles of the National Centers for Environmental Information (NCEI) world ocean atlas 2018 (WOA18) using the double gradient method along with the identity-index (i-index) showing the quality of the determination. With the identified (hT, hD) and (GT, GD), other parameters such as ITL heat content (HITL), mixed layer fresh-water content (FML), maximum thermocline gradient (GTmax), thermocline depth (hth), temperature at thermocline depth (Tth), maximum density gradient GDmax), pycnocline depth (hpyc), density at pycnocline depth (ρpyc), and (hT − hD) (barrier layer if positive or compensated layer if negative). The dataset is located at the NOAA/NCEI website (https://doi.org/10.25921/j3v2-jy50). It provides useful background information for ocean mixed layer dynamics, air-sea interaction, climatological studies. This paper is the only document for the dataset.
Ocean Sciences with the Spilhaus Projection: A Seamless Ocean Map for Spatial Data Recognition
Authors: Chen Jie , Zhang Tao , Tominaga Masako , Escartin Javier , Kang Ruixin
Published: June 2023

The ocean, as a vast interconnected body of water on Earth, plays an essential role in Earth’s planetary dynamics, climate change, and the evolution of human society and decision-making processes. An ocean-focused global map is necessary to visually capture numerous phenomena within the world’s ocean and seafloor. Here we present the power of the Spilhaus square projection with various geological and geophysical datasets, including bathymetry, teleseismicity, seafloor geography, and seafloor spreading parameters. The Spilhaus projection, compared to widely-used map projections (e.g., Mercator and Robinson), emphasizes the seamless connection of water masses surrounded by continents. This projection has recently garnered attention for presenting ocean-oriented data, although it is not extensively used and currently supported by the ArcGIS software. Maps presented here provide not only a novel geological perspective on the world ocean as a whole body, but also new insights/questions to be addressed regarding features and processes of the water body, the seafloor, and ocean-atmosphere dynamics, which can be used for research, education, media, and policy decisions, and promote similar approaches.
Simulated Inherent Optical Properties of Aquatic Particles using The Equivalent Algal Populations (EAP) model
Authors: Lain Lisl Robertson , Kravitz Jeremy , Matthews Mark , Bernard Stewart
Published: June 2023

Paired measurements of phytoplankton absorption and backscatter, the inherent optical properties central to the interpretation of ocean colour remote sensing data, are notoriously rare. We present a dataset of Chlorophyll a (Chl a) -specific phytoplankton absorption, scatter and backscatter for 17 different phytoplankton groups, derived from first principles using measured in vivo pigment absorption and a well-validated semi-analytical coated sphere model which simulates the full suite of biophysically consistent phytoplankton optical properties. The optical properties of each simulated phytoplankton cell are integrated over an entire size distribution and are provided at high spectral resolution. The model code is additionally included to enable user access to the complete set of wavelength-dependent, angularly resolved volume scattering functions. This optically coherent dataset of hyperspectral optical properties for a set of globally significant phytoplankton groups has potential for use in algorithm development towards the optimal exploitation of the new age of hyperspectral satellite radiometry.
HANDdata – first-person dataset including proximity and kinematics measurements from reach-to-grasp actions
Authors: Mastinu Enzo , Coletti Anna , Mohammad Samir Hussein Ali , van den Berg Jasper , Cipriani Christian
Published: June 2023

HANDdata is a dataset designed to provide hand kinematics and proximity vision data during reach to grasp actions of non-virtual objects, specifically tailored for autonomous grasping of a robotic hand, and with particular attention to the reaching phase. Thus, we sought to capture target object characteristics from radar and time-of-flight proximity sensors, as well as details of the reach-to-grasp action by looking at wrist and fingers kinematics, and at hand-object interaction main events. We structured the data collection as a sequence of static and grasping tasks, organized by increasing levels of complexity. HANDdata is a first-person, reach-to-grasp dataset that includes almost 6000 human-object interactions from 29 healthy adults, with 10 standardized objects of 5 different shapes and 2 kinds of materials. We believe that such data collection can be of value for researchers interested in autonomous grasping robots for healthcare and industrial applications, as well as for those interested in radar-based computer vision and in basic aspects of sensorimotor control and manipulation.
HeiPorSPECTRAL - the Heidelberg Porcine HyperSPECTRAL Imaging Dataset of 20 Physiological Organs
Authors: Studier-Fischer Alexander , Seidlitz Silvia , Sellner Jan , Bressan Marc , Özdemir Berkin , Ayala Leonardo , Odenthal Jan , Knoedler Samuel , Kowalewski Karl-Friedrich , Haney Caelan Max , Salg Gabriel , Dietrich Maximilian , Kenngott Hannes , Gockel Ines , Hackert Thilo , Müller-Stich Beat Peter , Maier-Hein Lena , Nickel Felix
Published: June 2023

Hyperspectral Imaging (HSI) is a relatively new medical imaging modality that exploits an area of diagnostic potential formerly untouched. Although exploratory translational and clinical studies exist, no surgical HSI datasets are openly accessible to the general scientific community. To address this bottleneck, this publication releases HeiPorSPECTRAL (https://www.heiporspectral.org; https://doi.org/10.5281/zenodo.7737674), the first annotated high-quality standardized surgical HSI dataset. It comprises 5,758 spectral images acquired with the TIVITA® Tissue and annotated with 20 physiological porcine organs from 8 pigs per organ distributed over a total number of 11 pigs. Each HSI image features a resolution of 480 × 640 pixels acquired over the 500–1000 nm wavelength range. The acquisition protocol has been designed such that the variability of organ spectra as a function of several parameters including the camera angle and the individual can be assessed. A comprehensive technical validation confirmed both the quality of the raw data and the annotations. We envision potential reuse within this dataset, but also its reuse as baseline data for future research questions outside this dataset.

Measurement(s)
Spectral Reflectance

Technology Type(s)
Hyperspectral Imaging

Sample Characteristic - Organism
Sus scrofa