bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Learning Outcomes - A Global Academic Challenge
Authors: Rakesh Dr. K. S. S. , Kalifungwa Dr. Patrick
Published: July 2023

Abstract: Changes in the assessment system, the learning environment, and the teaching and learning methodologies used in the classroom have resulted from the dramatic increase in students' access to higher education. After a lesson or series of lessons, students should have gained the information, skills, and abilities, as stated by the learning outcomes. This research used a qualitative methodology. Researchers used a questionnaire and in-person interviews as part of a qualitative methodology. Fivepoint Likert-scale questionnaires were distributed. There were both paper and online versions of the survey, and both were used to collect responses. The study's goals were to (a) identify the instruments and data collection methods currently being used by public and private universities to assess core research study student-learning outcomes, and (b) assess the degree to which these approaches to measurement were producing data that can be used for improvement. The schools' research study programs have identified certain learning outcomes as crucial to their success
Pesticide and Public Health: A Review
Authors: Sharma Dr. P. L. , Yadav Dr. Vipin Kumar
Published: July 2023

Abstract: Agadtantra, according to Acharya Sushruta, is a branch of Ayurveda that deals with the symptoms of various poisons, their combinations, and treatments for bites from poisonous animals like snakes, insects, spiders, rats, etc. The rising popularity of herbal medicines has also raised questions about the quality, efficacy, and safety of the raw materials used in their production, including food and fruits. Today, some people but the majority of foods contain highly polluted pesticide residue, and the public health is being impacted by the pesticide residue. Pesticides are the natural or synthetic agents are made to kill all types of pests. In different fields like agriculture, forestry, aquaculture, food industry etc. are use pesticides. The pesticides threaten public health and ecosystem by their higher consumption. For the importance of public health, WHO establish the classification of pesticides on the basis of toxicity with the comprehensive knowledge of classification of pesticides, gross use of pesticides can be minimized by using it judicially and it is helpful to public health & ecosystem
Desenvolvimento de microempreendimentos do setor cultural na região metropolitana do Rio de Janeiro
Authors: Da Costa Lima Thales Abreu , Da Gama Afonso Herlander Costa Alegre , Valente Ferreira Julio Cesar
Published: July 2023

O setor cultural representa quase 3% do PIB brasileiro, e emprega 5,5 milhões de trabalhadores, parte destes estão na informalidade e são "invisíveis" aos olhos do Estado. Os microempreendimentos do ramo da cultura são uma fonte de inovação a partir dos potenciais culturais locais. O objetivo desta pesquisa é capacitar a partir de uma estratégia de educação empresarial para microempreendedores culturais do Estado do Rio de Janeiro., com a finalidade de gerar novas oportunidades de negócios e renda. A pesquisa contempla as seguintes etapas/fases metodológicas: a Fase 1 compreende uma análise de dados da organização NaProCult; na Fase 2, foi elaborada um treinamento, validado por meio de um painel de especialistas; na Fase 3 realizou-se uma pesquisa-ação para a execução da capacitação, cujos resultados foram avaliados na Fase 4, por meio de um survey. Os resultados mostram que os fazedores de cultura têm pouco acesso a uma educação voltada para seus empreendimentos, como frameworks que proponham novas formas de gestão para o mercado de trabalho atual.
PET/CT with various radiopharmaceuticals in the complex diagnosis of medullary thyroid carcinoma: a review
Authors: Tsentr N. V. , Ertman A. E. , Ryzhkova D. V.
Published: July 2023

INTRODUCTION: Medullary carcinoma is a rare malignant neuroendocrine tumor of the thyroid gland. Medullary thyroid carcinoma (MTC) has no specific clinical symptoms. Due to the absence of specific symptoms, the disease is usually diagnosed at the stage of metastatic lesions of regional lymph nodes, and sometimes, internal organs. The five- and ten-year survival after detection of distant metastases is 25% and 10%, respectively.

OBJECTIVE: To analyze the available foreign and domestic literature to determine the role of PET/CT with various radiopharmaceuticals in the complex radiological diagnosis of MTC.

MATERIALS AND METHODS: A search was made for scientific publications and clinical recommendations in the information and analytical systems PudMed, elibrary over the past ten years, dedicated to the diagnosis of MTC, including PET/CT with 18F-DOPA, 18F-FDG, 68Ga-DOTA peptides, etc. by keywords «medullary thyroid cancer», «medullary thyroid carcinoma», «PET/CT», «18F-L-dihydroxyphenylalanine», «18F-DOPA», «18F-DOPA», «68Ga-DOTA peptides», «68Ga-DOTA-peptides», «theranostics», «theranostics».

RESULTS: The analysis of publications demonstrated the prospects for the use of PET/CT with various radiopharmaceuticals for the diagnosis of recurrent tumors and the prevalence of the process in biochemical recurrence of MTC, as well as the possibility of peptide-receptor radionuclide therapy for the treatment of advanced forms of the disease. The choice of radiopharmaceuticals is based on the results of laboratory diagnostics and conventional methods of anatomical imaging. PET/CT with 68Ga-DOTA peptides is performed to predict the effectiveness of peptide-receptor radionuclide therapy.

CONCLUSION: PET/CT with various radiopharmaceuticals makes a significant contribution to the diagnosis of recurrent tumors, assessment of the prevalence of the tumor process and selection of patients for peptide-receptor radionuclide therapy.
Personality Features That Contribute to Transition of Young People from Unregistered Marriage to Marital Relations
Authors: Poznyakov Vladimir P. , Poddubny Sergey E. , Panfilova Yuliya M.
Published: July 2023

The study examined the role of personality traits and value orientations of young people (both men and women) as factors contributing to the transition from an unregistered marriage to marital relations. The differences in the severity of personality traits and the importance of individual values among the partners living in unregistered and registered marriages were revealed. The sample of the study included two groups of respondents aged 18 to 35: partners in an unregistered marriage (cohabitation) - 144 persons (men and women 50% each) and partners in a registered marriage - 120 persons (men - 42.5%, women - 57.5%). The research methods and tools included: S.H. Schwartz’s Values Questionnaire (Personality Profile Section), 50-point form of L. Goldberg’s Five-Factor Personality Inventory and a scale for assessing the intention to marry and commitment to have and raise children. The results of both questionnaires were processed using the Multipsychometer hardware-software diagnostic complex, which converted the initial test scores into a 10-point equal-interval Sten scale. The presence and nature of the statistical influence was established using multiple linear regression analysis, statistical differences were identified using Student’s t -test and Mann - Whitney U -test. According to the results of the study, the personality trait “agreeableness” was the leading factor in the commitment to have and raise children as well as in the readiness to register a marriage with a partner. The significant differences in the severity of personality traits and the significance of individual values in the partners who were in a registered and unregistered marriage were identified statistically. It was found that the respondents in a registered marriage, compared with their counterparts in an unregistered marriage, had significantly more prominent personality traits such as “agreeableness” and “emotional stability” and, for them, the values “universalism”, “benevolence” and “self-direction” were more important. The obtained results can be used to scientifically substantiate practical recommendations for managers and specialists involved in the support and development of the family institution in modern Russian society, as well as in the practice of individual and family counseling.
Theoretical Bases for Designing a Methodology of Training Teachers for Intercultural Interaction
Authors: Dzhurinsky Alexander N. , Zhukova Tatiana A. , Bogoslovskiy Vladimir I. , Andreeva Ekaterina Yu.
Published: July 2023

The intensification of the processes of globalization and integration of cultures has set before many multi-ethnic countries the task of building a multicultural society that develops according to the laws of tolerance, cooperation and mutual respect. This problem is particularly acute in the regions due to the differences in ethno-cultural and migration processes in any of them, different degree of dynamics and constant changeability of these processes. These factors determine the specific nature of training teachers for intercultural interaction in each particular region. Currently there is a situation when it is impossible to use a unified experience in training teachers for intercultural interaction equally in a single region: it is obvious that each region needs its own methodology. This determines the relevance of the research due to the existing trend of dynamic regional development under the influence of migration and ethno-cultural processes as well as the necessity to find mechanisms for training teachers for intercultural interaction in the dynamic ethno-cultural environment of the region through the analysis of various precedents. Thus, the purpose of this study is to design a methodology for training teachers for intercultural interaction in the context of dynamic ethno-cultural processes. Research objectives: to analyze the current state of knowledge of the problem of training teachers for intercultural interaction in the system of higher pedagogical education in Russia, as well as the current state of international studies on the problem of multicultural education based on the ideas of inter-ethnic dialogue; and to develop an algorithm for designing a methodology for training teachers for intercultural interaction in the context of dynamic migratory and ethno-cultural processes in the regions. The results of the study make it possible to propose a systematic algorithm for designing a methodology for training teachers for intercultural interaction based on the generalized regional experience; and to characterize the content of each stage of this algorithm. The study expands the ideas about the training of teachers for intercultural interaction in an ethno-cultural region, the specifics of implementing the principle of regionalization and comparative studies. The proposed methodology will make it possible to identify general, particular and single changes in the training of teachers for intercultural interaction, taking into account the regional specificity and dynamism of ethno-cultural processes in each region.
Contributions of Individual Intellectual Integrations to the Academic Achievement of Humanities Students
Authors: Dorfman Leonid Ya. , Kalugin Alexey Yu.
Published: July 2023

The contributions of individual intellectual integrations to the academic achievement of humanities students from the standpoint of the system’s principle, the system-integrative approach and the concept of dual systems were studied. System 1 (integral individuality) and system 2 (intelligence and creativity) were considered in the context of the cultural and educational environment. The purpose of the study was to identify the effects that this dual system produces on the academic achievement of students. The effects were tested under two conditions: (1) systems 1 and 2 operated together, and (2) systems 1 and 2 operated in parallel and separately. The study involved 415 humanities students of higher educational institutions of Perm, including 293 females and 122 males aged 17 to 22 years ( M = 18.6; SD = 1.0). Specially developed methods were used to study the properties of individuality (nervous system, temperament and personality), indicators of crystallized and/or fluid intelligence, and indicators of creativity (fluency, originality and flexibility). During the study, three models (full, correlated and uncorrelated) were developed and tested. The full model had an acceptable fit with the data and indicated the contribution of Conscientiousness (system 1) and Crystallized Intelligence (system 2) to the academic achievement. The correlated model was in good fit with the data and indicated the contribution of Conscientiousness , Neuroticism (system 1), and Crystallized Intelligence (system 2) to the academic achievement. Taken together, these properties explained 19% of the variance in the academic achievement. The uncorrelated model was consistent with the correlated model, except for the integration of systems 1 and 2, and was badly fitted to the data. The results of the study correlated well with the results of meta-analyses. The individual intellectual integrations were limited and selective. They affected some variables but did not touch other ones. Thus, the considered dual system functions rather jointly than separately.
Mentoring Technologies in Psychotherapy, Education, Management and Intercultural Relations: Results of the International Psychological Forum at the Russian-Armenian University
Authors: Berberyan Asya S. , Bashkin Evgeniy B. , Bzhoyan Elene A. , Ermakov Dmitry S. , Amantay Zhuldyz
Published: July 2023

On May 16-17, 2023, the Russian-Armenian University (RAU; Yerevan, Republic of Armenia) hosted the International Psychological Forum “The Phenomenon of Mentoring: an Existential-Humanistic Paradigm and Implementation Technologies in Education, Management, Psychotherapy and Intercultural Relations”. The objectives of the Forum included (1) finding solutions to urgent problems of personal development through mentoring in the field of psychology, education, management, production, research, creative activities, etc.; (2) discussing scientific results and innovative technologies in the field of mentoring; (3) exchanging experience; and (4) establishing creative contacts. The forum brought together more than 100 participants (heads of scientific and educational organizations, scientific and pedagogical workers, practical psychologists, postgraduate and graduate students) from Armenia, Belarus, Germany, Kazakhstan, Kyrgyzstan, Russia, the Czech Republic, Israel, etc. The article presents the main events that included plenary and breakout sessions, roundtable discussions, interactive lectures, master classes, and a teleconference.
Location of links in the pharmaceutical value chain in Сhina: the role of contract research organizations
Authors: Volgina Natalia A. , Li Na
Published: July 2023

Cross-border pharmaceutical value chains are expanding their presence in international production, including in the highly profitable RD link. Leading pharmaceutical companies, known as Big Pharma, are establishing contract relationships with research organizations in many countries around the world, including emerging economies where China plays a very significant role. The purpose of this study is to assess the placement and location of Chinese contract research organizations in the RD links of the international pharmaceutical chain. As a result of the study, the authors came to the following conclusions. The development of the Chinese market can be dated to the beginning of the 2000s, when outsourcing firms for large international pharmaceutical companies began to be created. The Chinese market for contract research organizations has developed at a faster rate compared to the world market. As the key explanations for the rapid development of the Chinese market, the authors highlight the strong state support of the Chinese government, the improvement in the quality of research services provided by Chinese companies, as well as the lower price of these services compared to competitors. Market development relies primarily on the close ties of Chinese contract research organizations with Big Pharma companies. Demand from local Chinese pharmaceutical companies and from foreign affiliates of small and medium-sized of pharmaceutical companies located in China plays an increasing role in stimulating the market for contract research organizations. The rapid development of the Chinese market for contract research organizations has been accompanied by its consolidation and concentration, as well as monopolization in some market subsectors. Market consolidation was also supported by the accelerated pace of MA in pharmaceutical RD amid the pandemic.
Foreign trade relations between Russian Federation and Syrian Arab Republic in terms of Eurasian integration
Authors: Tinkova Arina A. , Digilina Olga B. , Alkanj Alabseh Yamen
Published: July 2023

The issues of the relevance of foreign trade cooperation between Russia and Syria, including the opportunities and risks of the Syrian economy for partners; the current state of bilateral trade between Russia and Syria; Syria as a promising direction for the Russian export business and the need for its development are considered. The authors analyzed the foreign trade potential of the dynamics and structure of foreign trade relations, identified comparative advantages in the world commodity markets, determined the place and role of bilateral foreign trade partnership. Russia is one of the key export markets for Syrian agricultural products, whose price competitiveness is supported by zero preferential duties within the framework of the unified system of preferences of the Eurasian Economic Union. In the course of the study, the authors identified the volume of unrealized export potential of Syria to the EAEU countries and vice versa, including in the structure of goods. It is concluded that it is necessary to develop trade relations on a bilateral basis with the help of instruments aimed at raising awareness of consumer demand and supply of national producers, as well as through “soft power” instruments in the field of education. It seems that Syria’s obtaining observer status in the EAEU will become an incentive to strengthen trust relations and investment attractiveness, which, in turn, will become the basis for joint work on infrastructure cross-border logistics projects in Syria (the Five Seas Strategy) and will reduce costs for increasing mutually beneficial bilateral trade. The study contains theoretical and statistical justification, as well as practical proposals for the development of friendly relations and strategic partnership with the Syrian Arab Republic in the context of the development of integration processes of the Eurasian Economic Union.
Current state and prospects of development of China’s seaports
Authors: Semenova Nelli K.
Published: July 2023

From an economic point of view, ports contribute to the comprehensive development of cities and can have a comprehensive stimulating effect on the economy of the interior. As a hub connecting various modes of transport, such as railways, highways, aviation and pipelines, ports are an indispensable component of the state’s transport network. During the gradual improvement of the Chinese transport system. At the same time, ports are the gateway for the foreign trade of a country or region. The efficiency of ports is directly related to the effectiveness of foreign economic cooperation. In addition, the development of ports is closely linked to the economic security of the country. Ports initiate the socio-economic growth of the region, serve as a center of social activity. Ports are also a major source of employment, as ports employ a large number of workers. The emergence of China as a great maritime power is becoming a fait accompli before our eyes. In the context of profound changes in the domestic and international macro environment, the port industry of the People’s Republic of China is accelerating the pace of transformation and modernization, adhering to new development concepts and providing strong support for the economic development of the state. The study reveals China’s modern leadership in the global port industry, formed in the fierce competition of the largest ports in East Asia. The stages of development of the ports of the People’s Republic of China and the role of the planned economy in this process, the modern structure of the port economy of the People’s Republic of China and the leading ports of the country are analyzed. New trends and prospects for the development of both continental and foreign ports of the People’s Republic of China are considered. The paper analyzes the place of the People’s Republic of China in the modern world port industry, determines the stages of development of China’s ports and the role of the planned economy in this process, studies the modern structure of the port economy of the People’s Republic of China and the country’s leading ports, identifies new trends and prospects for the development of mainland and foreign ports of the People’s Republic of China, analyzes key trends and problems underlying recent changes in the the port system of China. To date, there has not been a comprehensive study in the Russian bibliography that gives a general idea of the role of the port economy in the development of the PRC economy and China’s leadership in the port and shipping industries of the world. The present study aims to fill this gap.
Assessment of the effectiveness of budget financing of innovative Russian universities
Authors: Kovelsky Viktor V. , Rostova Elena P.
Published: July 2023

The research is devoted to the study of the effectiveness of public funding of innovative universities of the Russian Federation that participated in the 5-100 project and have the status of national research universities. Analysis of the spending of taxpayers’ money has always been one of the important elements of federal accounting and control of any state. The 5-100 project itself was an important milestone in the development of Russian universities and in increasing their competitiveness in the international market. Of course, like any significant project with significant funding, “5-100” in all the years of its existence caused a variety of emotions, from complete delight to complete rejection. One of the elements of negative rhetoric was the investment of federal funds for the development of the scientific research of universities. However, during numerous inspections, no significant violations were identified, and the results of the project were found to be satisfactory. At the same time, the authors of this article were interested in exploring the deeper layers of the 5-100 project the relationship between the territorial components and a number of important indicators, such as, for example, publication activity, income from scientific research and a number of others. Based on the analysis of statistical data, the heterogeneity of the ratio of RD results and the volume of budget financing of universities was revealed, and the influence of the territorial factor on the studied indicators was shown. Based on the analysis of eight indicators characterizing the publication activity of university employees and the volume of RD funding, the universities considered in the study are divided into three clusters without considering the territorial feature. The analysis made it possible, among other things, to identify the uneven distribution of budgetary funding for RD. The authors explain this effect by the territorial features of universities, when regional universities receive less funding compared to universities in the Central Federal District and the North-West Federal District. At the same time, not all universities of the Central Federal District and the North-West Federal District are distinguished by a high number of publications in domestic and foreign information and analytical systems of scientific citation. Yet, even with the distribution of funds, which could be more efficient, the significance of the 5-100 project for the development of the higher education system is still great and the current most important projects of the Ministry of Education and Science, such as Priority 2030, continue the best that was in project “5-100”.
Assessing the impact of technological sanctions on computer equipment imports
Authors: Naumov Vladimir N. , Zhiryaeva Elena V.
Published: July 2023

The purpose of the study is to assess the risks of economic modernization caused by technological sanctions. Hypothesis: the imposed sanctions had little effect on actual imports of computer hardware components to Russia. Since the sanctions under consideration have been tightened since 2014, it was assumed that there were no fundamental changes in the structure and volume of imports. Analysis of the US export control system showed that there are four reasons for controlling the export to the Russian Federation of a number of computers and their components. For export to the Russian Federation and Belarus all applications for licenses are considered with a presumption of denial. The embargo policy provides for the restriction of exports to Russia of goods of headings 8541 (semiconductor devices) and 8542 (electronic integrated circuits). Enterprises that are considered military end users are restricted from exporting to them chips with high processing speed. The embargo covers quantum computers that are believed not to be manufactured in Russia. The dominant subheadings in the import structure are 8542 31 (microprocessors) and 8542 39 (other integrated circuits). Clusters of exporting countries have been constructed using the methods of principal components and multidimensional scaling. It is established that the main ones are China, Taiwan, Vietnam and Malaysia. Next, an analysis of the dynamics of imports was performed to test the hypothesis. Graphical, quantitative methods of the theory of time series, methods of mathematical statistics and regression analysis are used. For countries without export controls the increase in imports to Russia over 15 years, both in terms of processors (160 %) and integrated circuits (224 %), was an order of magnitude greater than for countries with export controls. As the share of imports from countries without export controls increases, the significance of sanctions decreases, which confirms the formulated hypothesis. At the same time, the “foreign direct product” rule, which allows the US to control exports from Taiwan, could negatively affect this dynamic.
China’s arms trade: trends and challenges
Authors: Reshetnikova Marina S. , Shvets Sergey S.
Published: July 2023

Over the past decade, China has made significant progress in the development of the defense industry; today, China is able to produce almost all the nomenclature items of weapons, military vehicles, and ammunition. The aim of the research is to analyze China’s successes in the development of the defense sector; it is highlighted that the Chinese military-industrial complex has reached the point of technological self-sufficiency at this time. The essential features of the public-private partnership model (“the triple helix”) are considered. The authors tracked the evolution of China’s export regulations as they related to the selling of goods from the militaryindustrial complex. The share of Chinese military-industrial complex exports in the global arms market is revealed. The study shows the escalation of US-Chinese rivalry in the field of building up military capacities and establishing export ties. Trade in military-industrial complex products is a means for China to achieve its foreign policy goals. The authors discuss possible areas for improving the country’s export strategies and vectors of geographical coverage of foreign trade, as well as barriers and difficulties in the development of foreign trade in military-industrial complex products.
Diversification of Transport Links in the “Asia — Europe” Container Shipping Traffic
Authors: Shcherbinin N. V. , Rusinov I. A.
Published: July 2023

In the modern foreign economic conditions, the development of container shipping through the system of international transport corridors in the Eurasian space is one of the key aspects in order to improve the national transport complex and to ensure the economic sustainability of the federal subjects of Russia. The object of this research is the «Asia-Europe» segment of the container transportation market, the research subject is to make assessment of the feasibility of the container shipping routes diversification in Eurasia.

Aim. To consider the possibilities of the Russian transport system in conditions of restructuring supply chains and container shipping intensification through the international transport corridor “West — East”.

Tasks. To identify the directions of increasing the competitiveness of the Russian Federation container system; to determine the main routes of the ITC “West — East» system; to implement the statistical analysis of container shipping data in Russia; to complete the comparative analysis of container transportation through ITC “West — East” and through alternative routes in the “Asia — Europe” connection.

Methods. The collection of the data on the main ITC “West — East” routes in accordance with the following systems: Organisation for Cooperation between Railways (OSJD), Eurasian Development Bank (EDB), Directorate of International Transport Corridors (DITC), Russian Foreign Trade Academy (RFTA), Centr Ekonomiki Infrastruktury (CEK).

Results. The research of the relevant container shipping routes of Russian goods in the current industry conditions and the consideration of the main advantages of containerized cargo delivery routes diversification in the “Asia — Europe” connection were carried out.

Conclusions. The demand for container transportation routes passing through ITC “West — East” has increased in parallel with the process of cargo flows redirection. Diversification of containers delivery routes leads to significantly reduction of the transit time and support the development of the national transport system.
On Issue of Current Development of Tourism between Russia and China
Authors: Yagya T. S.
Published: July 2023

The article is devoted to Russian-Chinese tourism cooperation. It noted that this cooperation is a promising direction in the development of relations between Russia and China. The article examines the state of development of Russian-Chinese tourism cooperation, reveals the factors that attract Chinese tourists to Russia. It tells about the growing trend of Chinese interest in Russian tourist destinations. The article pays attention to the importance of the Russian-Chinese tourism forums held every year, as well as the importance of the “Visit Russia” tourism office. It talks about the successful work of the Russian tourism association “World Without Borders” and the Chinese Association of travel companies. The article reveals a number of unresolved problems in the development of the Russian-Chinese tourism industry, and also indicates the measures taken by the Russian and Chinese governments, which led to activity in the development of Russian-Chinese bilateral tourism. Prospects in the development of tourism in Russia and China, as well as measures to restore the tourism industry after the Covid-19 pandemic are considered.

Aim. To investigate present status and development of Russian-Chinese tourism.

Tasks. To analyze present status of development of Russian-Chinese relations in the field of tourism, to identify their features and problems; to find out opportunities of Russian tourism market focused on Chinese tourists and possible ways to develop tourism between two countries.

Methods. This article is created based on empirical methods such as comparative analysis, as well as theoretical research methods such as deduction, the method of historical analysis, statistical methods, general logical methods (analysis and synthesis).

Results. The research showed great importance of cooperation between Russia and China in the field of tourism for two countries. This cooperation contributes to the growth of incomes of local population due to creation of a large number of new jobs, the improvement of communication and information infrastructure and an increase in level of involvement of countries in globalization processes. The results of the research are based on the analysis of data obtained from various available sources, including official statistics.

Conclusion. The importance of cooperation between Russia and China in the field of tourism and in the development of both Russian and Chinese economies in the XXI century is great. It seems to us that it is the merit of both Russian and Chinese governments supporting development of partnership relations in the field of tourism.
Integrity and Singularity: on a Civil Law Protection of the Privacy in the Countries of the Eurasian Economic Union
Authors: Volfson V. L.
Published: July 2023

The article assesses the need for a privacy right to be enshrined in the Russian civil law. In effect, the issue is whether time is ripe for the protection of a universal right that would cover all personal interests. Aim. To propose and substantiate civil law protection of the privacy by means of a single subjective right. Tasks. To submit the rationale for enshrining a universal personal right, to offer a concept of the privacy as a protectable legal asset, to respond to possible objections, to demonstrate advantages of a unified legal regime.

Methods. Alongside general scientific approaches, the methods used in the research include interpretation technique, comparative jurisprudence, applying assessment of law efficiency based on its concept as a way to harmonize private interests.

Results. While the idea of personal space is making its way to a greater identity in the minds of the Russian people, the civil legislation provides protection to such interests only in cases provided for by the law. However, the judicial protection of all personal interests by default outside the legal regime would be an inefficient solution. The author offers his own theory of privacy as a legal category. Apart of providing defense for any relevant interests, legal recognition of a single personal right will allow to identify features of protectability, to stipulate the exemptions, and make easier for the courts to deny protection in cases of abuse of the right.

Conclusions. The development of civil legislation is increasingly lagging behind the need in protection of personal interests. The author stands up for a single personal right to be enshrined in the law. The crucial test is whether such a right live up to expectations of the parties of relations in question, i.e. citizens of Russia, rather than the extent to which such a rule is recognized by other jurisdictions.
Prediksi Penjualan Tabung Gas LPG 5,5 kg di PT. Parafin Energi Mandiri dengan Menggunakan Metode Least Square
Authors: Oktavia Aulia , Nita Sri , Putra Roni Tri
Published: July 2023

PT. Parafin Energi Mandiri (PT. PEM) merupakan sebuah perusahaan yang bergerak di bidang pemasokan dan penjualan gas LPG non subsidi. Masalah yang sering muncul dalam berbisnis LPG adalah seringnya terjadi kelangkaan atau jumlah permintaan LPG 3 Kg yang mengakibatkan masyarakat beralih mengkonsumsi gas LPG non subsidi. Penelitian ini bertujuan untuk mengetahui prediksi jumlah penjualan tabung gas 5,5 Kg oleh PT. PEM pada Juni 2022 – Mei 2023 dengan menggunakan metode least square. Persamaan trend yang diperoleh adalah Y^'=850,083-12,631 X. Persamaan tersebut merepresentasikan bahwa akan terjadi penurunan penjualan tabung gas 5,5kg dari bulan ke bulan pada periode Juni 2022 – Mei 2023. Tingkat akurasi dari persamaan trend di atas adalah sebesar 10%. Artinya, persamaan trend tersebut dapat digunakan untuk memprediksi penjualan di bulan-bulan selanjutnya karena hasil prediksi yang dilakukan sangat akurat. Sehingga hasil prediksi penjualan tabung gas 5,5kg untuk 12 bulan mendatang (Juni 2022 – Mei 2023) dapat dijadikan pedoman dalam mengatur strategi penjualan agar nilai penjualan yang diperoleh maksimal. Tren penurunan ini juga terjadi pada angka jumlah penjualan tabung gas 5,5kg. Jumlah penjualan pada periode Juni 2021 – Mei 2022 adalah 10.201 tabung dan menurun menjadi 6.728 tabung pada periode Juni 2022 – Mei 2023. Kata kunci : Prediksi, Metode least square, Persamaan trend, Tingkat akurasi
Karakteristik Aljabar Lie Nonsolvable aff(2)
Authors: Kurniadi Edi , Kartiwa Alit
Published: July 2023

Dalam artikel ini, dipelajari tentang aljabar Lie affine berdimensi 6 yang sekaligus merupakan aljabar Lie Frobenius. Terdapat fungsional linear atau 1-form yang mengakibatkan aljabar Lie affine merupakan aljabar Lie Frobenius. Tujuan penelitian ini adalah untuk membuktikan bahwa fungsional linear tertentu yang dipilih dapat dihitung secara eksplisit dan berkorespondensi dengan struktur 2-form. Diberikan juga pemetaan antara aljabar Lie affine dengan ruang dualnya yang juga didefinisikan berkaitan dengan 2-form-nya. Hasil yang diperoleh menunjukkan eksistensi fungsional linear tersebut mengakibatkan adanya skew-symmetric nondegenerate closed 2-form yang merupakan turunan pertama dari fungsional linearnya.  Selanjutnya, dihitung juga elemen utama dari aljabar Lie affine berdimensi enam.

Kata kunci : Aljabar Lie Affine, Aljabar Lie Frobenius, Fungsional Linear, 2-Form, Ruang Vektor Dual.
Development of Physics Learning Devices in High School Based on Science Technology Engineering and Mathematics (STEM) Assisted by Android in Dynamic Electricity Subject Matter
Authors: Ansar Mohammat Ari , Werdhiana I Komang , Darsikin Darsikin
Published: July 2023

This research is a development research with a 4D development model. The study was conducted in class XII IPA 1 and IPA 2 in SMA Negeri 1 Moutong, each class consisted of 25 students. The instruments used were observation sheets, test questions and documentation. The data obtained consisted of experimental class data and control class data. For Cognitive tests in the experimental class, data were obtained that the percentage of graduation was 89%, while for the control class the percentage of graduation was 76%. For the attitude assessment, in the experimental class the total percentage of all meetings was 84,4%, while in the control class the total percentage of all meetings was 79%. For the Skills assessment, in the experimental class the total percentage of all meetings was 80%, while in the control class the total percentage of all meetings was 76%. For Percentage of Activity of Students, in the experimental class the total percentage of all meetings was 81,3%, while in the control class the total percentage of all meetings was 79,1%. Then from the process of analyzing Validity, Reliability, Difficulty Index, and Differences in the items it was found that, 24 items were received from a total of 25 items submitted. As well as in the interview results were found, namely a positive response from the teacher and students interviewed. The performance of the Android application is very good, able to calculate each score of the experimental class students in 0 (zero) seconds. So, it was concluded that the learning devices developed and assisted with Android were valid, practical and effective quality.
Title Successful Prenatal Treatment with Continuous Chronic Maternal Hyperoxygenation Therapy in Hypoplastic Left Heart in Two Pregnancies: Case report
Authors: Gedikbasi Ali , Bolluk Gokhan , Oztarhan Aylin , Vural Cagdas , Oztarhan Kazim
Published: July 2023

ABSTRACT Maternal hyperoxygenation (MH) has been studied as a
diagnostic tool to evaluate pulmonary vasculature and as a treatment
option to improve the growth of fetal left heart in fetuses with
left-sided cardiac defects. Chronic maternal hyperoxygenation (CMH)
therapy leads to an improvement in fetal pulmonary blood flow resulting
in an enhanced venous return to the left heart with increased
gestational age. With this manipulation it is anticipated to augment
blood flow directed remodeling of the left heart structures and to
improve left heart growth spanning from the mitral valve to the aortic
isthmus. However, there are concerns about CMH therapy with regard to
fetal complications with growth restriction and fetal brain development.
Now, with two successful cases we try to discuss this fetal treatment
option and related concerns.
NRF2 signaling in cytoprotection and metabolism
Authors: Murakami Shohei , Kusano Yusuke , Okazaki Keito , Akaike Takaaki , Motohashi Hozumi
Published: July 2023

The KEAP1-NRF2 system plays a central role in cytoprotection and defense
mechanisms against oxidative stress. Because KEAP1 serves as a biosensor
for electrophiles by using its reactive thiols and because NRF2 is a
transcriptional factor regulating genes involved in the sulfur-mediated
redox reactions, the KEAP1-NRF2 system has been regarded as a
sulfur-utilizing cytoprotective mechanism. NRF2 is a key regulator of
cytoprotective genes, such as antioxidant and detoxification genes, and
also to possess potent anti-inflammatory activity. NRF2 has been
recently focused as a great modifier/regulator for the cellular
metabolism and mitochondrial function. Particularly, the NRF2-mediated
regulatory mechanisms of metabolites and mitochondria has been
considered diverse, but has not been fully-clarified yet. This review
article provides an overview of the molecular mechanisms that regulate
NRF2 signaling and its cytoprotective roles, and also highlights NRF2
contribution to the cellular metabolism, particularly in the context of
mitochondrial function and newly found sulfur metabolism.
Enhanced immunity against to SARS-CoV-2 in returning ex-patriot Chinese
Authors: Sun Jiufeng , Yuan Runyu , Chen Huimin , Yi Lina , Li Xinxin , Hu Ximing , Li Xing , Zhang Huan , Zhou Pingping , Liang Chumin , Lin Huifang , Zeng Lilian , Zhuang Xue , Ruan QianQian , Chen Yueling , Deng Yingyin , Liu Zhe , Lu Jing , Xiao Jianpeng , Chen Liang , Xiao Xincai , Li Jing , Li Baisheng , Li Yan , He Jianfeng
Published: July 2023

Background Global COVID-19 vaccination programs effectively
contain the fast spread of the SARS-CoV-2. Characteristic the immunity
status of returned populations will favor for understanding the
achievement of herd immunity and long-term management of COVID-19 in
China. Methods Returning travellers were recruited from 7
quarantine stations in Guangzhou, China. The immunity statuses of
participants were determined through Competitive ELISA,
Micro-Neutralization Assay and Enzyme-Linked FluoroSpot Assay.
Results A total of 272 subjects were involved in questionnaire
survey, in which 235 (86.4%) were returning ex-patriot Chinese and 37
(13.6%) were foreigners. Blood and throat swabs specimens were
collected from each of 108 returning ex-patriot Chinese. The
neutralizing antibody against SARS-CoV-2 was detected in
~90% of returning ex-patriot Chinese, either in the
primary or the homologous and heterologous booster vaccination group.
The serum NAb titers of them were significantly decreased against
SARS-CoV-2 Omicron BA.5, BF.7, BQ.1 and XBB.1 compare with prototype
virus. However, memory T cell responses including specific IFN-γ and
IL-2 were no differences in either group. Smoking, drinking, SARS-CoV-2
infection, COVID-19 vaccination, and the time interval between last
vaccination and the sampling were independent influencing factors for
NAb titers against prototype SARS-CoV-2 and variants of concerns. The
dose of vaccination was the unique common influencing factor for Omicron
variants. Conclusions The herd immunity was established in
returning ex-patriot Chinese who exposure to the complicated infection
and vaccination circumstance. Domestic residents will benefit from
booster of COVID-19 vaccines either in homologous and heterologous
vaccination after re-opening of China, as well as breakthrough
infection.
Gut microbial assembly among freshwater Atlantic salmon reared in a natural stream system during a simulated farm escape and introgression event
Authors: Schaal Patrick , Cheaib Bachar , Heys Chloe , Kaufmann Joshka , Phillips Karl , Ryder Liz , McGinnity Philip , Llewellyn Martin
Published: July 2023

Intestinal microbial communities are influenced by a confluence of
ecological forces. Understanding the dynamics between environment,
microbiota and host is essential to gain insights into microbial
community assembly processes. However, few studies systematically assess
the contribution of different environmental sources to gut microbial
community composition. We used a common garden experiment to determine
the roles of biotic, abiotic and stochastic processes shaping gut
microbial communities in Atlantic salmon (Salmo salar) in a
natural river during a simulated 10-month farm escape scenario. Most of
the taxa found in the salmon intestine originated from
macroinvertebrates (the potential food source) rather than the water
column, indicating that diet is an important factor in community
assembly. The contribution of food sources to the fish gut community was
lowest in winter and increased over March and May, reflecting
seasonality in fish appetite. Previous work in salmon has hinted at a
role for maternal effects in driving inter-generational sharing of
microbial taxa. Our results suggest a possible host and/or maternal
genetic effect affecting inter-individual differences in gut microbial
community composition, whereby distinct assemblages were noted between
farmed, wild and hybrid fish. Neutral modelling estimated that the
majority (86%) of taxa present in the gut are transient. Overall, our
data highlight the significance of both deterministic and stochastic
drivers influencing the seasonal fluctuations of gut microbial
communities in young Atlantic Salmon and hint at potential genetic or
maternal effects on fish microbiota. These findings greatly enhance our
understanding of the complex interactions between hosts, their living
environment and associated microbiota.
The Therapeutic Effect of Bismuth Subsalicylate in a Propionic Acid-Induced Autism Model
Authors: Koenhemsi Lora , Güneş Berzah , Eroğlu Ebru , Erbaş Oytun
Published: July 2023

Backround and Aim: Autism is a clinically well-defined disorder
that has no treatment yet. Other than behavior modification studies,
medical treatments are still investigating. Rat is among the most
frequently used experimental animals in such studies. Although various
drugs cause autism in this animal species, propionic acid (PPA) was used
in this study. Bismuth subsalicylate is frequently used in the treatment
of gastrointestinal diseases in clinics and has anti-inflammatory and
antacid effects. In our study, we examined the effects of bismuth in
rats with autism using PPA. Materials and Methods: Thirty male
rats were used in this study and 20 of them were given PPA
intraperitoneally at 250 mg/kg/day for five days. Rats were randomly
divided into three groups: Group 1 (no procedure was applied, n=10),
Group 2 (intraperitoneal PPA+1 ml/kg/day % 0.9 salines given orally,
n=10), and Group 3 (intraperitoneal PPA+60 mg/kg/day bismuth
subsalicylate given orally, n = 10). After 15 days of treatment;
behavioral tests, blood tests, and histopathology samples were taken.
Results: A significant improvement was observed in autism-like
behaviors in rats treated with bismuth. Tumor necrosis factor-alpha
(TNF-α), Interleukin-17 (IL-17), IL-6, prostaglandin E2 (PGE2), and
malondialdehyde (MDA) levels decreased, and brain-derived neurotrophic
factor (BDNF) levels increased in the bismuth group.
Conclusion: This study showed that bismuth can be used in
addition to other treatments for autism. However, further studies on the
subject are needed.