bluuebunny/crossref_metadata_2025 huggingface dataset:
A Critical Review of English Narrative Teaching Practices From the Perspective of Brain Cognitive Science
Authors:   The Korean Society For Teaching English Literature, Yoon Goosaang
Published: January 2024

This paper explores the intersection of brain cognitive science and teaching English narrative reading, identifying three key brain characteristics observed during this process. Firstly, the brain fills in information gaps from incomplete sensory data. Secondly, it actively engages in imaginative and experiential involvement with the narrative, facilitated by the action-perception circuit and mirror neurons. Thirdly, narrative reading activates the Default Mode Network, prompting self-exploration. Despite these insights, textbooks, teaching methods, and assessments exhibit discrepancies, with a focus on didactic messages, grammar, and language testing. This paper advocates for a shift towards immersive narrative reading experiences by integrating brain cognitive science findings. It proposes four reading approaches—inferential, experiential, imagery, and scene reading. Bridging these gaps can enhance education by encouraging direct engagement, imaginative exploration, and alignment of assessments with teaching goals, fostering a deeper connection between students and narrative texts.
Improving Critical and Creative Thinking Skills in English Education: A Proposal for Narrative Text-Based Assessment in CSAT
Authors:   The Korean Society For Teaching English Literature, Choi Seokmoo
Published: January 2024

The 2015 and 2022 Revised English Curricula emphasize critical and creative thinking skills, but CSAT lacks appropriate evaluation items for these skills. To bridge this gap, this study proposes creating assessment questions that measure these skills using narrative texts. Crafting multiple-choice questions with narrative texts proves challenging due to their interpretative nature. To tackle this challenge, the study suggests formulating questions that require interpreting texts from specific perspectives, thereby constraining the meaning of the narrative texts. Two questions were created following these principles and validated as appropriate for the national college entrance exam. Most high school students and English teachers positively assessed both questions, confirming their suitability for evaluating critical and creative thinking skills in the national exam. Teachers find [Question 2] more challenging than [Question 1] due to its sole use of narrative texts, leading to less effective evaluation of critical and creative thinking skills—a problem stemming from teacher training programs discouraging the integration of narratives in English education.
Teaching English to Children Using Narrative Texts: Anthony Browne’s Gorilla
Authors:   The Korean Society For Teaching English Literature, Yang Yunjeong
Published: January 2024

This study discusses the educational value of narrative texts in order to utilize them in English education for elementary school and younger children. As children are born with the storytelling gene, listening to stories and storytelling are language acquisition methods close to children’s nature. In addition, the English curriculum was revised in 2022 to achieve ‘English communicative competence.’ Sub-competencies are presented as ‘cooperative communication,’ ‘knowledge information processing,’ ‘creative thinking,’ ‘self-management,’ ‘community,’ and ‘aesthetic sensibility’ (Ministry of Education, 2022c), emphasizing emotional aspects. Therefore, English education using narrative texts is urgently required. This study discusses academic and practical considerations to utilize narrative texts more effectively. Furthermore, it analyzes Anthony Browne’s picture book Gorilla as an example and creates a lesson plan.
Current Status and Prospect of Yann Martel Research in Korea: Focusing on Papers Published in Domestic Academic Journals from 2015 to 2023
Authors:   The Korean Society For Teaching English Literature, Park Jungman
Published: January 2024

More than 20 years have passed since 2002 when the novel Life of Pi and author Yann Martel’s name began to become known in Korea with the winning of the Man Booker Prize, and since 2004 when the novel was translated and published in Korea. Additionally, about 10 years have passed since the novel was adapted into a film in 2012, and the film Life of Pi was released in Korea the next year of 2013. It has been at least 10 or as long as 20 years since Yann Martel’s name was imprinted in the memory of Korean readers and the film public. At this point a question arises. So, how has Yann Martel been remembered during this period, not by readers and the film public, but by Korean academics? In other words, how has Yann Martel ‘research’ developed in Korea over the past 20 years to the present? Responding to the question, this study examines the development and status of Yann Martel research in Korea, focusing on research papers published in domestic academic journals over the past 20 years to date, to be precise, from 2015 to 2023. To this end, a quantitative analysis of the papers and a qualitative analysis of the topic and content covered by the papers will be conducted together. As a conclusion, this study will diagnose the challenges and future prospects left by the current Yann Martel research in Korea.
Vexas Syndrome: A Newly Discovered Hemato Inflammatory Disease
Authors: M Hamed Nahla A
Published: January 2024

VEXAS syndrome is a recently described hemato inflammatory disease. It is an acronym from the syndrome’s key characteristics: vacuoles in bone marrow biopsies, low levels of ubiquitin activating enzyme (E1 enzyme), X-linked, autoinflammatory, somatic. It results from a somatically acquired mutation affecting methionine 41 of the E1-ubiquitin ligase UBA1, leading to the expression of a catalytically impaired isoform that drives inflammation. As this gene is located on the X chromosome, only men appear to be affected by this syndrome. Patients have severe inflammatory symptoms that affect multiple organs. Clinical features bridge rheumatological, dermatological, ophthalmological, respiratory, and hematological conditions. There is an association between severe autoinflammatory manifestations and myeloid dysplasia.
Antifungal Activities of Copper Surfactants Derived from Neem (Azadirecta indica) and Karanj (Pongamiapinnata) Oils: A Pharmaceutical Application
Authors: Sharma Arun Kumar
Published: January 2024

Different methods were applied on Neem and Karanj oils; their Copper (II) soaps and also their Copper (II) soaps benzothiazole complexes to study their comparative fungicidal study. To find the biological activity different methods were used i.e. Antifungal Disk Diffusion Susceptibility Testing of Yeasts; approved Guideline (M 44-A, NCCLS, USA) and antifungal testing of Alternaria alternata suggested by Booth and Hawks worth. The testing was done on two species of Candida i.e. C.albicans and C.krusei. Antimicrobial disks used were Fluconazole, Amphotericin, Clotrimazole and Ketoconazole. These antimicrobial disks were used as standard, as the strains of Candida albicans and Candida krusei are susceptible to them. The diameter of zones of testing disks was compared with the zone diameter of these standards antimicrobial agents.
The Mysterious Domination of Food Contaminants and Adulterants in Bangladesh
Authors: Mohiuddin AK
Published: January 2024

Food adulteration and contamination are as old as the civilization itself. It is the consequence of the development of civilization, over utilization of nature, industrialization and in fact a price for the progress. It is highly prominent in Urban areas of Bangladesh. It is the consequence of commercialism of business people who are doing this knowingly to maximize profit. Higher degree of awareness shown by the people with higher educational background. Government regulatory agencies are less confident regarding food standard testing, as reported in the study. People with higher educational background show higher degree of awareness of how the quality of food should be maintained. A lack of confidence on the functions of government regulatory agency in testing the food standard is also reflected in the study. Safe food means, in general, there will be no danger from harmful elements such as pathogenic microorganisms, naturally occurring toxins and other potentially harmful chemicals that are deliberately added to food products in the country. The economic development of this country rarely reveals the basic literacy and consciousness of mass people. Necessary steps are to be taken to protect the environment for our own existence.
Complementary and Alternative Medicine: Evaluation of the Physicochemical and Thermal Properties of the Biofield Energy Treated Metronidazole
Authors: Jana Snehasis
Published: January 2024

Metronidazole is an antibiotic and is useful for antibacterial and antiprotozoal medication. In this research work, the impact of the Trivedi Effect® (Consciousness Energy Healing Treatment) on the physicochemical properties of metronidazole was evaluated using the modern analytical technique. Metronidazole sample was divided into two parts, one part of metronidazole was considered as a control sample (no Biofield Energy Treatment was provided); however, the other part of metronidazole, was exposed to the Consciousness Energy Healing Treatment remotely by a well-known Biofield Energy Healer, Alice Branton and termed as a treated sample. The peak intensities, as well as crystallite sizes of the treated metronidazole were significantly altered ranging from -97.25% to 463% and -83.18% to 123.79%, respectively; however, the average crystallite size was significantly decreased by 14.91% compared with the control sample. The particle size values in the treated metronidazole were significantly decreased by 14.69%(d10), 10.82%(d50), 19.14%(d90), and 16.88% {D (4,3)}; thus, the specific surface area was significantly increased by 24.7% compared to the control sample. The latent heat of fusion and latent heat of decomposition were decreased by 2.1% and 9.41%, respectively in the treated sample compared with the control sample. The total weight loss was increased by 2.56%; however, the residue amount was significantly decreased by 83.86% in the treated sample compared with the control sample.
Phytochemical Characterization and Antioxidative Property of Ocimum canum Sims
Authors: Revathilakshmi S
Published: January 2024

Medicinal plants are the richest bio-resource of drugs for traditional systems of medicine, modern medicine, nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates and chemical entities for synthetic drugs. In the present study aimed to find out the phytochemicals present in the various solvent leaf extracts of Ocimum canum Sims and all the fractions of O. canum demonstrated H-donor activity. The highest DPPH radical scavenging activity was detected in chloroform fraction (IC50 0.145mg/ml), followed by ethyl acetate, pet-ether and residual fractions (IC50 0.164, 0.29 and 0.6mg/ml respectively). The residual fraction of O. canum showed the highest reducing ability (absorbance 0.620) than all the other fractions tested. The scavenging activity of the pet-ether fraction (IC50 0.141mg/ml) was higher than that of quercetin (0.308mg/ml). The residual, chloroform and ethyl acetate fractions also showed significant scavenging activities (IC50 of RF, CF and EAF were 0.125, 0.186 and 0.232mg/ml respectively) when compared to the standard. The chloroform fraction showed strong nitric oxide scavenging activity (IC50 0.183mg/ml) and that of standard curcumin was 0.078mg/ml. The total antioxidant activity of the fractions of O. canum was determined by the thiocyanate method and compared with the standard, a-tocopherol. The phosphomolybdate method is quantitative, since the total antioxidant capacity is expressed as α-tocopherol equivalents. Among the fractions tested, the chloroform fraction showed the highest ferrous ion chelating ability (IC50 0.276mg/ml). Moreover, total phenolics concentration equivalents to gallic acid was found in the range of 59.50 to 109.0mg/g of plant extracts, which correlated with antioxidant activity. The findings indicated promising antioxidant activity of crude extracts of the above plants and needs further exploration for their effective use in both modern and traditional system of medicines.
Tea Diversification Products and Value Addition
Authors: Goswami Tridib Kumar
Published: January 2024

This mini review focuses on the issues leading to the development of wide range of value added tea diversification products and the associated health benefits either as nutraceutical beverage or confectionary items or in the form of toiletries and cosmeceuticals being commercialized in different parts of the world that are gaining consumer acceptance and also a win over strategy to face the global marketing challenges by tea industries.
Formulation Design for Poorly Water-Soluble Drug by Using Solid Dispersion of Telmisartan for Solubility and Dissolution Rate Enhancement
Authors: Paul A Deevan
Published: January 2024

Formulating the drug into solid dispersion (SD) by fusion method and solvent evaporation method using different grades of PEG in comparison to plain telmisartan drug with optimised solid dispersion tablets. The Preformulation studies like FTIR and DSC studies for drug excipient compatibility stated that the drug and carrier selected for the study and are compatible for further studies. SD was prepared by using the drug Telmisartan by two methods, fusion method and solvent evaporation method, eighteen formulations were prepared and characterized in terms of various parameters. The in vitro drug for all the formulations were in the range of 82.38%-95.73% for fusion method and 91.45% to 96.81% for solvent evaporation method and tablets it ranges from 95.70% to 99.40%. The in-vitro release studies have shown that the cumulative drug release values were within the range of 14.23%-94.54% for fusion method, 18.57%- 95.89% for solvent evaporation method and 14.35% - 99.53% for tablets. The fast drug release about 99.53% was found in the F22 formulation by solvent evaporation method in solid dispersion tablets in the ratio of 1:2 and drug content was found to be 99.53% and disintegration time was 1.09 seconds and all parameters were found to be greater than all other formulations.
Conventional Surgery or Minimally Invasive Osteosynthesis for the Diaphyseal Fractures of the Tibia
Authors: Plain Pazos Claribel
Published: January 2024

Introduction. Tibial fractures are common injuries. Minimally invasive osteosynthesis, with conventional percutaneous plate, has been described as a technique that seeks to preserve soft tissue viability as much as possible. Method. A prospective, longitudinal, coasi-experimental study is carried out on surgical treatment of tibial fractures, using theoretical and empirical research methods. Results. The largest number of patients belong to the male sex (n=89), adults between 40 and 59 years old, with fractures of the middle third of the tibia, mainly short oblique line and with average times for the intervention in the conventional approach group is of 2.89 days, average surgical time of 73.8 minutes and 8.89 days of stay, with significant differences compared to the MIPO group where the average time for the intervention is 3.10 days, average surgical time of 38.2 minutes and 3.36 days of stay. The group treated with MIPO shows earlier consolidation (1.5 weeks) Conclusions. Minimally invasive osteosynthesis has advantages regarding the reduction of surgical times, complications and consolidation.
Traumatic Hip Dislocation Associated with Iatrogenic Proximal Femoral Physeal Fracture in Children: A Systematic Review and Case Report
Authors: Mohammed Hushlul Sulaiman
Published: January 2024

Background: Traumatic hip dislocation (THD), which accounts for 3% of all joint dislocations in children which is a rare condition. pediatric hip dislocation with transphyseal femoral neck fracture accounts for less than one percent of all hip injuries. Less than 8% of hip fractures and 1% of pediatric fractures are caused by femoral head and neck fractures. A high rate of complications is linked to transphyseal femoral neck fracture related THD. Avascular necrosis, premature epiphyseal closure, nonunion, soft tissue loss injuries in open fracture-dislocation that necessitate negative pressure wound therapy, leg length discrepancy, coxavara, and the angular deformity that goes along with it are list of these complications.
The Effect of Schroth Exercises on Pulmonary Function in Adolescent Idiopathic Scoliosis
Authors: Tunc Hande
Published: January 2024

Background: Idiopathic scoliosis is a three-dimensional structural deformity and adolescent form is the most common type (AIS). Conservative treatment methods in AIS include brace and scoliosis-specific exercise treatments. Respiratory limitations have been reported in relation to the nature of scoliosis itself. However, the evidence regarding treatment interventions is controversial. The purpose of the study, to investigate the effects of Schroth exercises on pulmonary functions on adolescents who use rigid braces and perform Schroth exercises.
Kajian Pustaka: Faktor-Faktor Risiko Penyakit Mulut dan Kuku pada Hewan Pemamah Biak (Ruminansia) Kecil
Authors: Pamungkas Pandu Adjie , Putra Putu Dian Purnama , Nugraha Gede Wiyasa Ardy , Candrayani Putu Prema , Jesus Carmelita Soares de , Batan I Wayan
Published: January 2024

Penyakit Mulut dan Kuku (PMK) merupakan penyakit akut yang sangat menular. Selain itu, virus penyakit mulut dan kuku diketahui menghambat pertumbuhan dan reproduksi pada hewan ruminansia kecil. PMK merupakan penyakit yang sangat penting karena menyerang ternak ruminansia dengan seroprevalensi keseluruhan sebesar 11,48%. Saat ini, wabah penyakit mulut dan kuku sedang meningkat di Indonesia sehingga tulisan ini diharapkan dapat menjadi informasi yang berguna untuk menekan penyebarannya. Tinjauan pustaka yang digunakan pada studi literatur ini yaitu menggunakan penelusuran pustaka dengan melakukan pencarian artikel jurnal yang terkait dengan topik yang akan dibahas yaitu faktor risiko PMK pada ruminansia kecil dari beberapa sumber seperti artikel-artikel pada Frontiers in Veterinary Science dan Google Scholar. Faktor risiko pada hewan ternak ruminansia kecil yang berhubungan dengan seropositif PMK meliputi agroekologi, sistem produksi, umur, jenis kelamin, kontak dengan satwa liar, iklim, ras, interaksi dengan ternak lain, manajemen, dan sanitasi ternak. PMK diduga awalnya terjadi di Italia Utara pada tahun 1514 dan di Afrika Selatan pada tahun 1780. Penyakit ini memiliki morbiditas yang tinggi hingga 100% dan mortalitas yang rendah. Berdasarkan hasil pustaka ini dapat disimpulkan bahwa ditemukan adanya beberapa faktor risiko penyakit mulut dan kuku pada ruminansia kecil terdapat lima yaitu spesies, ras, umur, jenis kelamin, dan asal hewan. Mengingat terbatasnya penelitian yang telah dilakukan hingga saat, perlu dilakukan penelitian lebih lanjut mengenai kejadian penyakit mulut dan kuku terutama pada ruminansia kecil.
Disorientasi Zakat Cultural-Based Deviance on Islamic Law; Zakat Tekke Wale’ Spending in Basala, Konawe, Southeast Sulawesi, Indonesia
Authors: Kamaruddin  , Misbahuddin  , Suprijati Sarib  , Syamsul Darlis
Published: January 2024

Owners of swallow's nest in Basala District, South Konawe Regency give zakat of tekke wale' (swallow's nest) using gold zakat rate. This implies deviation from Islamic law and striking difference from the provisions of zakat law formulated by most Muslim scholars. This research aims to reveal the business phenomenon and practice of tekke wale' zakat spending, the factors beyond preference to use zakat with gold rate as well as culture-based deviations on Islamic law regarding this specific practice of zakat. This research is qualitative with an empirical-normative approach which includes interviews with swallow nest owners, community leaders, and religious leaders. Besides, it involves literature review to gather the data. The research shows that swallow nest business is a relatively new livelihood for local people so they have no definite guidance on how to spend the zakat. Their preference using gold zakat rate are due to five factors, ranging from lack of knowledge, assumption that swallow's nest is not a part of agricultural business, easy calculation in giving zakat using gold rate, following the previous swallow's nest owners, to easiness to determine the zakat recipients and spending period. Meanwhile, three forms of deviation from Islamic law existing at the practice urges the specific legal product concerning this specific commodity.
Tagyîr Mawdhî’ Inhirâf Qiblat al-Masjid fî Bamîkasân ‘alâ Asasi al-Tiknôlôjiyya al-Mutaqaddimah: al-Tahlîla al-Ijtimâ’î wa al-Tsaqafî
Authors: Elhas Hosen , Abdul Jalil  , Abd. Wahed  , Ach. Muzayyin  , Ziyad Ravaşdeh
Published: January 2024

Reposition of wrongly-established qibla direction typically brings into controversy, particularly among takmir as the mosque officiants. However, what occured in Pamekasan shows different trends. This research therefore focuses on how the Pamekasan based takmir responded on the qibla direction reposition issue. It is a descriptive one based on qualitative data. The data was collected using interview to the takmir  and participatory observation at the research locus. The obtained data was then sorted and systematically arranged for verification to draw a conclusion. The research comes to a conclusion that; first, the deviation of qibla direction on the research locus was caused by wrongly-determined direction in the initial mosque building process due to the ignorance of Islamic astronomy or so called ilmu falaq theories. The mistake was figured out trough verification on the sun image and qiblat direction application. Second; the reposition was initiated by takmir who firstly consulted with experts on Islamic law and falaq, made scientific investigation by rechecking the mosque qibla direction using advanced technology, then announced the process result to the mosque congregation, and made a deliberation forum before doing the reposition replacing the older with the more accurate and newer one. Third; takmirs’ perception on the mosque qibla reposition tends to be supporting rather than opposing.
Soekertijo: The Lunge of Officers from Lumajang 1946-1988
Authors: Anggraeni Dwi Ayu , Suharto Suharto , Izzah Latifatul
Published: January 2024

This thesis discusses the role and career of Soekertijo during his time in the military. Soekertijo first entered the world of military education during the Japanese occupation of Indonesia, he graduated from Pembela Tanah Air (PETA). After Indonesia's independence, he formed Section II. Soekertijo Company began to show its work in the national arena such as defending Indonesia's sovereignty from Dutch Military Aggression I and Dutch Military Aggression II, in addition, Soekertijo also cracked down on separatist groups such as DI/TII to PRRI. The approach used by the author is the Biography approach, while the theory used in this study is the Charisma Theory from Max Weber's writings. The writing of this thesis is more emphasized on Soekertijo's role when defending Indonesia's independence, is a history in the form of a biography, because it will narrate the events of Soekertijo's past as part of the process of forming his leadership spirit, adolescence and his journey before becoming a company commander to becoming a Major General. The temporality of this article began in 1946, which was the momentum for the success of Section II of Kompi Soekertijo in defeating the Dutch Military at Klakah Station, while the deadline for this article was 1988, marking the inauguration of the Juang Kompi Soekertijo Monument in Yosowilangun as a form of appreciation for his dedication to country.

Keywords: Soekertijo, Section II of the Soekertijo Company, Military, Dutch Military Agression and Separatist Group.
Megalithic Culture In Suboh Sub District Situbondo Regency
Authors: Handoko Nurcholis Fitrio , Swastika Kayan , Na'im Mohamad , Pratama Akhmad Ryan , Puja Gusti Ngurah Ary Kesuma , Jamil Robit Nurul
Published: January 2024

The megalithic culture in Suboh District, Situbondo Regency has its own uniqueness, namely the mortar stones, where the mortar stones in Suboh District have holes around the main hole, where the holes function to place crushed grain and there are also many archaeological remains that have not been recorded. The aim of this research is to add to the inventory of archaeological remains, social, economic and cultural systems. The type of research is qualitative research. The research methods are: (1) heuristics, (2) criticism, (3) interpretation, (4) historiography. Based on the research results, the typology of archaeological remains in Suboh District consists of three types, namely sarcophagi, stone mortars and stone monoliths with a hollow stone type. Community supporters of megalithic culture in Suboh District already know the concept of belief in the spirits of ancestors (acestor-worship). Social, economic and cultural life has recognized an egalitarian agricultural system.

Keywords: Culture, Suboh, Megalithic
Utilization Of the Sarekat Islam Building in Semarang As A Living History Learning Model for History Subjects During The Indonesian Movement
Authors: Khotimah Siti Khusnul
Published: January 2024

This article contains the history of the establishment of the Sarekat Islam building, including the background to the establishment of the building, its functions, and its development over time. Later from this research it can be linked to history learning, both in terms of its benefits and its application in education. The struggle of the heroes needs to be told to students clearly by utilizing historical relics such as buildings or objects related to historical events. The lack of interest of students in exploring history and the existence of historic buildings that have not been utilized optimally is the reason for this research being conducted. The introduction of the Sarekat Islam building will later use the living history learning model. This model utilizes the surrounding environment to channel learning objectives. It is expected that students can understand the meaning of learning history. The method used in this research is the literature study method. This means that researchers utilize previous sources related to the problem to be solved to complete the research. The purpose of this research is to encourage students to think chronologically, be active, and have a high spirit of nationalism. On the other hand, with this paper it is hoped that history educators can make historical references.

Keywords: Sarekat Islam Building in Semarang, living history, movement history
Soviet Union Spionage Arrest In Indonesia 1982
Authors: Ukasyah Syifa Surya , Puji Rully Putri Nirmala , Triyanto Jefri Rieski , Prasetyo Guruh , Soepeno Bambang
Published: January 2024

The purpose of this study is to analyze the events of the Soviet Union's espionage arrest in Indonesia in 1982. The formulation of the problem in this research is (1) The Soviet Union's Efforts to Steal Indonesian Maritime Data, (2) The Process of the Soviet Union's Intelligence Arrests for Espionage in Indonesia, and (3) the Settlement of the Soviet Union's Espionage Case in Indonesia in 1982. The method used is historical methodology which includes five selection steps including topics, heuristics, source criticism, interpretation and historiography. The Soviet Union's espionage arrest occurred in 1982 which was carried out by a task force codenamed Pantai, a joint effort between the State Intelligence Coordinating Agency (BAKIN) and a task force led by Brigadier General M.I Sutaryo. The cause of the Soviet Union's espionage arrest was an attempt to steal Indonesia's secret deep data regarding the condition, content and depth of the sea in the Lombok Strait and the Natuna Islands. The perpetrators of Soviet espionage who were caught by the Beach task force named Sergei Egorov and Alexander Finenko. The case settlement process was carried out by giving persona non-grata status and closing the Soviet Union's Aeroflot airline operating in Indonesia.

Keywords: Espionage Arrest, Soviet Union Espionage, Data Theft
Schopenhauer como educador
Authors: Peixoto Enock da Silva
Published: January 2024

Schopenhauer como educador é a terceira, das quatro Considerações Intempestivas e, nesta obra, o então mestre de Nietzsche figura como modelo de educador. Schopenhauer é visto por Nietzsche, neste momento, como um exemplo de gênio, pois figurou na sociedade como exceção, não como regra. A universidade da época e a estrutura estatal são reprovadas por Nietzsche, e, para as confrontar, ele as utiliza como chave de leitura crítica o pensamento do autor conterrâneo. Estudaremos, perpassando as análises que Nietzsche de que modo este autor figurou como alguém que apontou para uma educação intempestiva. Como essa postura de esforço de priorizar a singularidade pode ser configurada como perspectiva também artística.
The Potential Effect of Berberine on 5-Fluorouracil Induced Gastrointestinal Mucositis in Rats
Authors: KIRCADERE Melike , HARMANCI Nuşin , EROĞLU Ezgi , ÇENGELLİ ÜNEL Çiğdem , ŞAHİN Erhan , YİGİTASLAN Semra
Published: January 2024

5-Fluorouracil (5-FU), an antineoplastic agent, causes intestinal mucositis (IM) that limits the drug efficacy. The aim of this study was to reveal the protective and/or therapeutic effects of berberine (BER), an isoquinoline quaternary alkaloid, on IM induced by 5-FU in rats. Forty Wistar albino male rats were randomly divided into five groups: Control, 5-FU, 5-FU+BER75 (75 mg/kg/day), 5-FU+BER150 (150 mg/kg/day) and 5-FU+BER300 (300 mg/kg/day). 5-FU was intraperitoneally (i.p) injected at a dose of 60 mg/kg on alternate days for 4 days, while other groups were orally received BER daily for 7 days. By the end of study, intracardiac blood samples were collected and intestinal tissues were removed for histological examination. TNF-α, IL-6 and NF-κB levels were measured in serum using commercial ELISA kits. Results showed that BER at increasing doses ameliorated body weight loss and histopathological damage. It was concluded that BER may be effective in the treatment and/or prophylaxis of the damage in the gastrointestinal system caused by 5-FU in a dose-dependent manner.
“Not much room for mushrooms” in the heart: knowns and unknowns of fungal infective endocarditis
Authors: Mistiaen Wilhelm
Published: January 2024

Fungal infective endocarditis is a rare but highly lethal condition. Its diagnosis is often delayed due to nonspecific symptoms, inconclusive medical imaging, and negative blood cultures. Recent reviews of cases and series over the last 5 years indicate that the condition remains rare and lethal. If fungi are identified as the causative agents in more than 5% of patient cases with infective endocarditis, it is likely that risk factors such as immune suppression or cardiac implants are probably involved. A series derived from recent case reports indicates that Candida and Aspergillus are still the main causative infectious agents, with. C parapsilosis on the rise. From these cases, diagnostic clues (frequent embolisms, ophthalmic involvement, large, mobile and friable vegetation, non-valvular cardiac manifestations) are pointing towards fungal IE. These reports, however, are not standardized and a publication bias towards rare microorganisms or towards a favorable outcome might exist. Complications might be underreported, and important data such as diagnostic delay are absent or difficult to retrieve. Pharmacologic treatment is not fully standardized. Knowledge of resistant strains in this respect is important. Statistical analysis for the effect of complications and treatment modalities on outcome shows that any result should be treated cautiously. The current series is by no means a valid substitute for a well-designed series of fungal endocarditis. However, the better outcome with Candida and patients treated with surgery confirm earlier results. An international multicentric standardized registry of cases with fungal endocarditis in order to improve the outcome of this disease is highly needed. The effect of diagnostic delay on outcome remains elusive and should be resolved.
Perencanaan teknis kegiatan backfilling tambang batubara di CV Cinta Puri Pratama
Authors: Saputra Candra Andy , Triantoro Agus , Annisa Annisa
Published: January 2024

CV Cinta Puri Pratama mulai memasuki tahap mine closure yang ditandai dengan habisnya bahan galian yang ekonomis untuk ditambang sehingga menyisakan adanya lubang bukaan. Untuk melakukan penimbunan daerah tambang yang telah selesai di tambang, digunakan metode backfilling dengan memperhatikan volume material tanah timbunan dan lubang bukaan yang ingin ditutup. Setelah melakukan kegiatan penambangan diharapkan bekas lubang tersebut sesuai dengan kondisi semula meskipun tidak sempurna namun dikembalikan mendekati kondisi awal sebelum dilakukan penambangan. Metode backfilling yang digunakan dalam penelitian ini adalah metode full backfilling yang mana material yang tersedia langsung digunakan untuk menutup lubang bukaan. Dalam penilitian ini, perhitungan volume dibantu dengan menggunakan bantuan software minescape 5.7. Setelah melakukan analisis data, maka didapatkan volume lubang bukaan sebesar 588.882,95 m3 dengan volume material waste yang telah disediakan sebesar 5.497.229,16 m3. Perencanaan kegiatan tersebut menggunakan 2 fleet penambangan dengan masing-masing 1 unit Excavator Komatsu PC300LC-7, serta 5 unit alat angkut dump truck Scania P30 dan Faw J5-336. Proses kegiatan ini direncanakan selesai hingga akhir Maret 2019 dengan total biaya Rp 2.675.761.250,- perbulan.
Perencanaan reklamasi peruntukan lain pada lubang bekas tambang emas di wilayah pertambangan rakyat Provinsi Kalimantan Barat
Authors: Rivaldo Syafiq , Purwoko Budhi , Meilasari Fitriana
Published: January 2024

Kegiatan pertambangan rakyat atau yang biasa disebut PETI (Pertambangan Emas Tanpa Izin) mengakibatkan munculnya berbagai permasalahan lingkungan. Oleh karena itu, perlu dilakukan kegiatan reklamasi. Reklamasi merupakan salah satu cara pengendalian lingkungan akibat dari kegiatan pertambangan. Kegiatan reklamasi tidak hanya semata kegiatan revegatasi, tetapi dapat dilaksanakan dalam peruntukan lainnya seperti budidaya. Oleh karena itu tujuan dari penelitian ini adalah mengkaji pemanfaatan lubang bekas tambang terhadap pembangunan berkalanjutan terutama pemanfaatannya sebagai kolam budidaya. Penelitian yang dilakukan menggunakan metode kuantitatif. Dalam perencanaan reklamasi peruntukan lain sebagai kolam budidaya, kualitas air dan perencanaan sistem drainase merupakan hal utama yang harus diperhatikan. Parameter baku mutu air dalam perencanaan kolam budidaya yaitu pH, BOD, COD, Fe dan Hg. Hasil dari pengujian sampel air pada lubang yang akan dijadikan kolam reklamasi sudah berada di bawah ambang batas baku mutu air untuk kolam budidaya. Pada perencanan sistem drainase kolam, hasil perhitungan diperoleh debit air limpasan 0,65 m3/detik dengan perencanaan sistem drainase pada kolam sepanjang 123 m dengan bentuk trapesium.
Forma y construcción en las bóvedas de ladrillo: los casos de la Fuente Grande de Ocaña y el Ayuntamiento de Toledo = Form and construction in brick vaults: The cases of Ocaña Fountain and Toledo City Hall
Authors: Rabasa Díaz Enrique , López Mozo Ana , Calvo López José María
Published: January 2024

AbstractToledo City Hall and Ocaña Fountain, both works related in some way to Juan de Herrera, feature porticoes, of unknown authorship, with a series of brick vaults by slices, that is, with the main plane vertical or slightly pitched and the header face on the intrados, according to a very old craft technique which used no formwork. The article compares the two works on the basis of a precise survey and systematically analyses the brick arrangement, deepening in details that go beyond the mere bond description. It shows that, while those of Toledo present a conventional execution, in those of Ocaña the brick order is exceptionally regular and constant, and that the effort involved is consistent with the classical stone architecture it accompanies.ResumenEn el Ayuntamiento de Toledo y en la Fuente Grande de Ocaña, obras ambas relacionadas de alguna manera con Juan de Herrera, encontramos pórticos, de autoría incierta, con series de bó­vedas de ladrillo ejecutadas por hojas, es decir, con la tabla vertical o ligeramente inclinada y el canto o la testa visible en el intradós, según una técnica artesanal muy antigua que evita el uso de cimbras. El artículo compara las dos obras a partir de un levantamiento preciso, analiza siste­máticamente la disposición de las piezas, en detalles que van más allá de la mera descripción del aparejo, y muestra que, mientras las de Toledo presentan una ejecución convencional, en las de Ocaña el orden en la disposición de los ladrillos es excepcionalmente regular y constante y que el esfuerzo que esto supone es coherente con la arquitectura clásica en piedra a la que acompaña.
Un centro de investigaciones estéticas en el siglo XXX: una utopía de Francisco de Asís Cabrero = A center of aesthetic investigations in the 30th century: An utopia by Francisco de Asís Cabrero
Authors: De Coca Leicher José
Published: January 2024

AbstractIn the last of his Four Books on Architecture, Francisco de Asís Cabrero proposed in the year 3000 an International Institute of Aesthetic Experiences on the island of Vanikoro. It is a utopia, the result of his architectural research shown in each book: the vernacular origin (BI), the classical styles (BII), the «modern crisis» (BIII) and future times (BIV). At the same time, he accumulates his professional experience and the projects of unrealized «commemorative forms». We reviewed the project based on mathematical curves of evolution and the maximum human technology. We also go back through the Four Books looking for the references that allow us to understand the «lay out» of the project. The collective buildings of the avant-garde: the Unité d’Habitation, the Hele module by R. Leoz and the concrete art of M. Bill. Concepts such as «graphical science», «space grids», the «cubic figure» and «form-function inherence» allow us to understand the resulting form. The plants, not developed, are deduced from other realizations of the architect.        ResumenEn el último de sus Cuatro Libros de arquitectura Francisco de Asís Cabrero plantea en el año 3.000 un Instituto Internacional de Experiencias Estéticas en la isla de Vanikoro. Es una utopía, resultado de su investigación arquitectónica mostrada en cada libro: el origen vernáculo (LI), los estilos clásicos (LII), la «crisis moderna» (LIII) y los tiempos futuros (LIV). A la vez, recoge su expe­riencia profesional y los proyectos de las «formas conmemorativas» no realizados. Revisamos el proyecto fundamentado en curvas matemáticas de la evolución y el máximo tecnológico humano. También retrocedemos a lo largo de los Cuatro Libros buscando las referencias que nos permitan comprender las «trazas» del proyecto. Los edificios colectivos de las vanguardias: la Unidad de Habitación, el módulo Hele de R. Leoz y el arte concreto de M. Bill. Conceptos como la «ciencia grá­fica», las «redes espaciales», la «figura cúbica» y la «inherencia forma-función» permiten comprender la forma resultante. Las plantas, no desarrolladas, se deducen a partir de otras realizaciones del arquitecto.
Thinking Scripts
Authors: Marconi Valerio
Published: January 2024

Chinese traditional characters share with Peirce’s existential graphs the fact of being endowed with an object-language that they describe through a nonlinear syntax and in an iconic way. Here iconicity is not restricted to images and perceptive similarity since diagrams and graphic metaphors are iconic too. The graphs are shown to be a borderland between Western traditional logic and Chinese traditional writing and culture, so the écart (Jullien’s concept for cultural distance) between characters and graphs is preserved even though graphs break with the Western prejudice in favor of conventionality at the expense of iconicity in logical systems. The take-home lesson for the study of writing systems is to substitute the orality-writing duality with the interplay among orality, writing, and pictures thus shifting from a linguistic typology to a semiotic one.
Jean-Jacques Rousseau e sua política
Authors: De Morais Rodrigues Ubiratane
Published: January 2024

Tradução do artigo “Jean-Jacques Rousseau et sa politique”, de Eric Weil.
Sex Workers’ Professional Experiences in the Interplay of Structure and Agency in Croatia
Authors: Radačić Ivana , Antić Marija , Adamović Mirjana
Published: January 2024

There are still relatively few studies on job satisfaction and the quality of work ‎among sex workers, partly due to the ideologies surrounding sex work. In this ‎paper we move away from dichotomous thinking and investigate the professional experiences of indoor independent sex workers in Croatia against the ‎background of criminalised context and gendered socio-economic realities. ‎We look into sex workers’ motivations, perceptions and experiences, their ‎control and safety strategies.‎ The study shows that despite many structural constraints on the sex workers’ agency, all participants exercise some degree of autonomy and control ‎over their working lives. The factors that seem to be the most relevant in terms ‎of their ability to set up their own conditions, which in turn influences their experiences, are their economic situation, motivation and self-perception. Negative experiences mostly stem from criminalisation and stigmatisation of sex ‎work, which affects women primarily, and creates more risks to their health ‎and safety. The results of the study call for integrative policy approaches, ‎which presuppose full decriminalisation of adult voluntary sex work.
Prostate- Specific Antigen (PSA) Significance in Frail and Sarcopenic Men
Authors: Kostakopoulos Nikolaos A. , Bellos Themistoklis , Katsimperis Stamatios , Malovrouvas Evangelos , Papatsoris Athanasios
Published: January 2024

According to the guidelines of the European Association of Urology (EAU), it is recommended to exclude PSA testing when the expected remaining lifespan is less than 10 years. In this study, we provide a comprehensive analysis of the impact of prostate-specific antigen (PSA) testing on the quality of life of elderly men who are frail. We conducted a comprehensive literature review to identify publications that examine the use of PSA as a screening and prognostic tool for prostatic illnesses in frail men. Our search included the following keywords: Prostate-specific antigen, Frailty, Prostate cancer screening, Hypogonadism, and Benign Prostatic Obstruction (BPO). Prostate-specific antigen (PSA) testing can be used to identify prostate cancer in its early and treatable stages in fragile men with a life expectancy of over 15 years. Additionally, PSA testing allows for the evaluation of the effectiveness of various prostate cancer treatments and the monitoring of testosterone replacement therapy for hypogonadism. PSA is also indicative of the clinical development of patients with benign prostatic obstruction (BPO). Nevertheless, PSA is being extensively provided without individualised patient assessment, contributing to the economic strain on healthcare systems. Conducting a frailty evaluation on men to determine the potential advantages of PSA tests on their quality of life will help minimise avoidable expenses.
Effects of Different Temperature and Density on Quality and Microbial Population of Alfalfa Silage
Authors: Liu Jingyi , Hao Junfeng , Zhao Muqier , Yan Xingquan , Ge Gentu
Published: January 2024

In this study, alfalfa silage with different packing densities (500 kg/m3, 600 kg/m3 and 700 kg/m3) were set up under outdoor high temperature and indoor normal temperature. The chemical composition, fermentation quality and microbial community of alfalfa silage were analyzed. The results showed that DM and WAC content decreased with the increase of density. When the density is 600kg/m3, CP content reaches the maximum and ADF content is the lowest. Temperature has a certain effect on alfalfa silage. The content of Lactobacillus plantarum fermented at high temperature is lower than that fermented at normal temperature. At the same time, the content of Lactobacillus plantarum decreased with the increase of packing density. However, the content of Lactobacillus plantarum was the lowest when the packing density was 600 kg/m3 at high temperature. In summary, this study explained the effects of different temperature and density on alfalfa fermentation quality and microbial community, and clarified that the density should be reasonably controlled within 600 kg/m3 during alfalfa silage, providing theoretical support for production practice.
Spline Regression Mathematical Model for Obtaining a Sustainable Management in Young Beech (Fagus sylvatica L.) Stands
Authors: Crainic Ghiţă Cristian , Curila Mircea , Curila Sorin , Supuran Anamaria , Bica Alexandru Mihai
Published: January 2024

Having in view the sustainable management of forests, the intensity of silvotechnical interventions is analyzed and documented for young mixed beech stands regenerated naturally by taking into account the allometric relationships between some representative dendrometric elements, respectively, between the height of the trees and the corresponding diameter of their crowns. For this purpose, a functional dependence is established between the height and diameter of the tree crown from young beech stands within which silvotechnical interventions were or were not applied. A mathematical model based on cubic spline regression was developed, also taking into account the determination of the average diameter of the crown for each stand. This average diameter can be used to determine the optimal number of trees per surface unit (ha) at a given time. The research was carried out in three young beech stands, through statistical-mathematical inventories, on sample plots of 300 square meters with a tolerance of 10% and a coverage probability of 90%. The optimal diameter of the crown was obtained by applying the spline regression model, and the most appropriate functional dependence was established, resulting in a linear regression law with a positive slope.
Postprandial Plasma Glucose Measured from Blood Taken between 4 and 7.9 H Is Positively Associated with Mortality from Hypertension and Cardiovascular Disease
Authors: Wang Yutang
Published: January 2024

It is unknown whether postprandial plasma glucose measured from blood taken between 4 and 7.9 h (PPG4-7.9h) is associated with mortality from hypertension, diabetes, or cardiovascular disease (CVD). This study aimed to investigate these associations in 4,896 US adults who attended the third National Health and Nutrition Examination Survey. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of PPG4-7.9h for mortality. This cohort was followed up for 106,300 person-years (mean follow-up, 21.7 years). A 1-natural-log-unit increase in PPG4-7.9h was associated with a higher risk of mortality from hypertension (HR, 3.50; 95% CI, 2.34-5.24), diabetes (HR, 11.7; 95% CI, 6.85-20.0), and CVD (HR, 2.76; 95% CI, 2.08-3.68) after adjustment for all the tested confounders except hemoglobin A1c (HbA1c). After further adjustment for HbA1c, PPG4-7.9h remained positively associated with mortality from hypertension (HR, 2.15; 95% CI, 1.13-4.08) and CVD (HR, 1.62; 95% CI, 1.05-2.51), but was no longer associated with diabetes mortality. Subgroup analyses showed that similar results were obtained in the sub-cohort of participants without a prior diagnosis of myocardial infarction or stroke. In conclusion, PPG4-7.9h predicts mortality from hypertension and CVD independent of HbA1c.