bluuebunny/crossref_metadata_2025 huggingface dataset:
Lattice-matched growth of high-Sn-content (x∼0.1) Si1−x
Sn
x
layers on Si1−y
Ge
y
buffers using molecular beam epitaxy
Authors: Fujimoto Kazuaki , Kurosawa Masashi , Shibayama Shigehisa , Sakashita Mitsuo , Nakatsuka Osamu
Published: March 2023

Silicon tin (Si1−x
Sn
x
) layers with an Sn content of 11%, which is almost 100 times the solid solubility limit, have been successfully grown on lattice-matched Si1−y
Ge
y
surfaces using molecular beam epitaxy. The crystallographic analyses revealed that the Sn precipitation did not occur during the growth, even using a deposition temperature (T
d) exceeding the Si-Sn eutectic point (231.97 °C). Further, the epitaxial thickness could be increased from 20 to 100 nm with T
d from 250 to 350 °C without any Sn precipitation. Utilizing a lattice-matched Si1−y
Ge
y
buffer will be a powerful tool to realize epitaxial Si1−x
Sn
x
layers with various Sn contents.
OCULAR MORBIDITY AMONG COVID PATIENTS AT A TERTIARY CARE RURAL HOSPITAL
Authors: H V Dr Pooja , Vineel Sai Dr Ravulapati
Published: March 2023

Purpose: The aim of this study was to assess the ocular morbidity among the patients post SARS-CoV-2 infection. Methods: This is a prospective observational study conducted on patients post SARS-Co-V-2 infection, at a dedicated tertiary COVID-19 hospital in South India from June,2020 to August, 2021.A thorough history regarding the onset, duration, progression, nature of symptoms and its associated factors, medication history, treatment history were elicited and documented. Ocular examination was performed by an ophthalmologist with proper care. Further investigations including imaging were sought for, depending on clinical indications. A Results: total of 60 patients were examined. Of them, 41 (68.3%) were males and 19 (31.7%) were females, the age group ranged from 12 years to 62 years. On clinical examination, 45 (75%) developed ocular manifestations, of which 22 (48.8%) had features suggestive of Bilateral viral conjunctivitis solely,20(44.4%) had features suggestive of viral retinitis and 2(4.4%) had combined features of conjunctivitis and viral retinitis. 1 (2.2%) patient had developed Mucor mycosis. In our study, Viral retinitis was most common ocula Conclusion: r morbidity among the covid patients.This pandemic has changed our lives in many ways and various ocular morbidities were seen too, of which few cases recovered with timely diagnosis and management.
A CASE OF GLIAL HETEROTOPIA INVOLVING ROOT OF NOSE- A RARITY
Authors: Saha Sutirtha , Banerjee Pranabashish , Chowdhury Kanishka , Sikder Biswajit
Published: March 2023

Heterotopic neuroglial tissue represents normal brain tissue in an abnormal location away from the CNS. It is a rare congenital anomaly and the majority of these lesions are diagnosed at birth. We present this case report to highlight the occurrence of heterotopic glial tissue in the nose in children. It being a rare disease, very few articles in the literature have documented the occurrence of heterotopic glial tissue in extracranial sites. The entity put the surgeons in dilemma as to the diagnosis and managemen
A STUDY ON CLINICAL PROFILE OF SNAKE BITE IN TERTIARY CARE HOSPITAL
Authors: Kumar Dr. Mudige Arun , Babu Dr. V.O. Mahesh , Padmaja Dr. B. , Bheemasenachari Dr. M.
Published: March 2023

Aim and objective : To study the prevalence of poisonous and non-poisonous snake bites in Anantapur with reference to age, sex, occupation, part of body bitten, time of bite and and the types of poisonous snakes common in this locality and their clinical manifestations This is a descriptive study conducted between October 2021 to O Methods : ctober 2022 at a tertiary health care centre in Andhra Pradesh. Snake bites who were admitted and treated during this period were included in this study. The prevalence of poisonous and non-poisonous snake bites in Anantapur with reference to age, sex, occupation, part of body bitten, time of bite and seasonal variation, and the types of poisonous snakes common in this locality and their clinical manifestations were studied. Results : A total of 100 patients were studied. Out of 100, 72 patients were of poisonous snakebite and 28 patients were of non-poisonous snake bite. Out of these 72 poisonous snake bites, 38 were viperine snake bites, 22 were neuroparalytic snake bites and 12 were locally toxic snake bites. Among various manifestations snake bite with ischemic stroke is very rare which is observed in 3 cases during this period. Conclusion : Snake bite is still a dreadful condition. Delay in hospitalization is associated with poor prognosis and increased mortality rate due to consumptive coagulopathy, renal failure, and respiratory failure. Unusual complications like Disseminated intravascular coagulation (DIC) and ischemic stroke and myocardial infarction were observed in present study
ROLE OF EMF DETECTOR FOR THE INVESTIGATION OF LAMBI DEHAR MINES 10KM FAR FROM LIBRARY CHOWK MUSSOORIE
Authors: Habibullah Mansur , Rai Shyam Prakash
Published: March 2023

There are many unsolved questions which are haunting, these happen from many years. Actually many persons ask do ghosts really exist. In India there are many haunting place as in Kolkata Wipro Company where situated it's really haunted. In India 87% persons believe that ghost is exist all time. As that I visited the place Lambi Dehar Mines and it is infamous one of most haunted places in uttarakhand. This place is a ghost area and by EMF meter and I give rent two two ojhas and they went with me this time. By our research i faced many horror incidents. As I mentioned below
Genetic diversity of capsid protein (p24) in human immunodeficiency virus type-1 (HIV-1) variants circulating in the Russian Federation
Authors: Kuznetsova A. I. , Munchak I. M. , Lebedev A. V. , Tumanov A. S. , Kim K. V. , Antonova A. A. , Ozhmegova E. N. , Pronin A. Yu. , Drobyshevskaya E. V. , Kazennova E. V. , Bobkova M. R.
Published: March 2023

Introduction. The human immunodeficiency virus (HIV) protein p24 plays an important role in the life cycle of the virus, and also is a target for diagnostic tests and for new antiretroviral drugs and therapeutic vaccines. The most studied variant of HIV-1 in the world is subtype B. In Russia, the most common variant is A6, the spread of recombinant forms (CRF63_02A6, CRF03_A6B) is observed as well as circulation of G and CRF02_AG variants. However, a detailed study of the p24 protein in these variants has not yet been conducted. The aim was to study the features of the p24 protein in HIV-1 variants circulating in Russia and estimate the frequency of occurrence of pre-existing mutations associated with resistance to lenacapavir, the first antiretroviral drug in the class of capsid inhibitors. Materials and methods. The objects of the study were the nucleotide sequences obtained from the Los Alamos international database and clinical samples from HIV infected patients. Results and discussion. The features of HIV-1 variants circulating in Russia have been determined. V86A, H87Q, I91F are characteristic substitutions in A6 genome. It is shown that the presence of preexisting mutations associated with resistance to lenacapavir is unlikely. Conclusion. Features of the p24 protein in HIV-1 variants circulating in Russia allow them to be distinguished from others variants and among themselves. The prognosis for the use of lenacapavir in Russia is generally favorable. The results obtained could be taken into account in developing and using antiretroviral drugs and therapeutic vaccines.
Increasing Serum Levels of Nephronectin Based on Exposure Duration of Marble Dust in Industry Workers
Authors: Akbar Jimmy , Astuti Triwahju , Putra Ngakan Putu Parsama , Sari Fitri Indah
Published: March 2023

Background: Exposure to silica dust is still an occupational health problem worldwide. The marble industry is one of the industries at risk of causing respiratory disease in its workers. Exposure to marble dust in the airways triggers pulmonary fibrosis via nephronectin (Npnt) as an α8β1 integrin ligand, which is an extracellular matrix protein. The purpose of this study is to look at how serum nephronectin (NPNT) levels change over time after being exposed to marble dust. Methods: This was a cross sectional analytical study of marble industry workers. A significant difference test is carried out on 4 groups of subjects (n=50), including marble industry workers with exposure durations of 1-5 years (n=12), 6-10 years (n=14) and >10 years (n=14), as well as non-marble industry workers (unexposed) as control subjects (n=10). A correlation test was performed to see the relationship between duration of exposure and serum Npnt levels.Results: The median age value in the exposed group was 40.5 (20-67) years. There was a significant difference (P=0.012) in the median Npnt level of the exposed group [1.699 (0.22–5.27) ng/mL] and the non-exposed group [0.678 (0.21–1.96) ng/mL]. The median value of nephronectin levels in the 10 years exposed group [2.4710 (1.74–5.27) ng/mL] were significantly different with both the 1–5 years exposed group (P=0.0001) with a median value of 0.6960 (0.22–2.27) ng /mL and the 6–10 years exposed group (P=0.039) with a median value of 1.0480 (0.27–4.29) ng/mL. There was a significant (P=0.0001) positive relationship (r=0.633) between the length of exposure and the level of Npnt. Conclusion: The duration of marble dust exposure had a significant effect on serum Npnt levels. The longer the marble industry workers were exposed to marble dust, the higher the serum Nephronectin level.
IN-VIVO ASSESSMENT OF HYPOGLYCEMIC AND ANXIOLYTIC ACTIVITIES ON SWISS ALBINO MICE AND ANTHELMINTIC ACTIVITY ON EARTHWORM OF METHANOLIC EXTRACT OF MICROCOS PANICULATA LEAVES
Authors: Sadiatul Marzan  , Latifa Bulbul  , Md. Abdul Halim  , Md. Zahir Alam
Published: March 2023

The aim of the present study is to investigate the hypoglycemic, anxiolytic and anthelmintic activities of the methanolic extract of Microcos paniculata Leaves. The hypoglycemic activity was evaluated by measuring the blood glucose level of swiss albino mice, and anxiolytic activity was evaluated by hole board and elevated plus-maze tests on swiss albino mice. The anthelmintic activity was evaluated by measuring the paralysis and death times of adult earthworms. The methanolic extract of M. peniculata showed a highly significant (p< 0.001) hypoglycemic effect by reducing blood glucose levels with time, and the reduction is also dose-dependent. In the hole board test, the extract caused a large increase in the number of head dips. In the elevated plus-maze test, the extract caused a large increase in the amount of time spent in the open arm and a decrease in the amount of time spent in the closed arm. The extract showed highly significant (p< 0.001) anthelmintic activity by causing paralysis and death of earthworms in a short period, which is inversely proportional to increasing the concentration of extract. The evaluated results indicate the presence of hypoglycemic, anxiolytic and anthelmintic activities of this plant extract. Further investigation needs to be done to pick out the phyto-constituents responsible for these activities.
KEYWORDS: Hypoglycemic, Anxiolytic, Anthelmintic, Microcos paniculata Leaves, Swiss albino mice, Earthworms
Ryt z zamku krzyżackiego w Toruniu. Przyczynek do badań nad średniowiecznymi projektami elementów architektury na obszarze państwa zakonu krzyżackiego w Prusach
Authors: Szczupak Dominika
Published: March 2023

Ryt z zamku krzyżackiego w Toruniu w świetle analiz czytelnych obecnie żłobków oraz fotografii sprzed kilku lat daje się odczytać jako przedstawienie maswerku. Na podstawie dotychczasowych ustaleń badaczy na temat faz budowy toruńskiego zamku oraz jego topografii i układu przestrzennego podjęto próbę ustalenia chronologii wykonania rytu i funkcji obiektu, w którym się znajdował. Istotne znaczenie dla wyjaśnienia przyczyn wyrycia przedstawienia maswerku miało niewątpliwie odkrycie reliktów detali architektonicznych w obrębie zamku wysokiego oraz odnalezienie pewnych analogii z kościołem św. Jakuba w Nowym Mieście Toruniu.
Collaboration as 21st Century Learning Skill at Undergraduate Level
Authors: Musarrat Riaz  , Dr. Marium Din
Published: March 2023

This research work is about collaboration as an important learning skill of the 21st century skill set. Collaboration means to work to gather or to work as team to attain some certain common objectives. This research study highlights different advantages to work as a collaborative team. It covers both quantitative and qualitative aspects of the topic. Detailed interviews are conducted from students and as well a survey was also conducted to check to what extent students are using this skill of collaboration in their learning process. Six students from BS English and BS Education were selected for interview section and 200 students from BS English and BS Education were surveyed in this study. Both quantitative and qualitative results are analysed and conclusion is drawn on the basis of results. Convergent parallel mix method design is used to analyse the data. Data analysed with simple descriptive statics and thematic analysis of the conducted interviews. The results of this study shows that collaborative tasks are used among students in their process of learning but not at a larger scale. Group work and combine projects and assignments are included but just for once or twice in a semester.
Uttarakhand Movement: The Perspective of Political Parties and from the Eye of Media
Authors: - Naveen Prakash Nautiyal
Published: March 2023

In the post-independent period of India, most of all the political parties have involved in some form to affect the claim of separate hill state Uttarakhand from the Uttar Pradesh because of its specific topographical circumstances, economic activities, the exceptional cultural uniqueness of region, existence, practices and many more. Subsequently understanding the many grounds which controlled to the Uttarakhand separate state movement, it is authoritative to recognize the contribution of political parties in the identical. Major focus of this paper is to analyse the role of several national/regional political parties in the Uttarakhand separate state movements which intended at the demanding of separate for this specific region.

In late decade of eighties, mass movement for state for hilly Uttarakhand selected up push and question of separate state again came into the priority position. In the year of 1994 when the Uttar Pradesh state government stated 27 percent reservation for the Other Back Classes in government jobs and education, there were youth agitation all over hills against the reservation. By way of the OBC represents only 2 to 3 percent of the hill region, the step to save 27 percent seats for OBC, was consideration baseless and unpractical. The matter of reservation for the OBCs converted in mobilizing youth to backing the call for a separate Uttarakhand state. The very first time in the demanding of the mass movement youths involved in such record numbers, till now they were perceptible by their absenteeism.

The demand to call back 27 percent reservation for the O.B.Cs quickly transformed into the reservation to whole of hilly region. Finally, all the issues remained into the background and the require of statehood ship came into front in the entire mass movement. Males were all the time involved in the movement but the questions which needed bigger demand for women were employment opportunities, choices for their children and the increasing usage of liquor by men in the hills. These were the issues which directly involve the happiness of their families.
Since 1952 three models of separate governmental setup for Uttarakhand have been suggested from time to time: first, a complete state comparable to other states in Indian Union; second, an autonomous Uttarakhand and; third, Union Territory type. The first form initiates support with the Uttarakhand Kranti Dal. The second was advocated by the C.P.I. and the Uttarakhand Sangharsh Vahini till 1989. The Indian Congress party had constantly favoured Union Territory category for Uttarakhand (Pathak 1989:40-47).
Faktor Internal dan Eksternal Pelayanan Makanan yang Mempengaruhi Kepuasan Pasien di Ruang Rawat Inap Kelas 3 RSUD Budhi Asih Jakarta Timur
Authors: Nurdini Dahlia , Wijayanti Wiwit
Published: March 2023

Pelayanan makanan merupakan salah satu kegiatan pelayanan gizi di Rumah Sakit. Faktor Internal Pelayanan Makanan yang meliputi variasi makanan, warna, aroma, tekstur dan cita rasa serta Faktor Eksternal Pelayanan Makanan seperti penampilan dan keramahan petugas, kebersihan alat dan penampilan makanan. Penelitian ini bertujuan untuk mengetahui faktor internal dan faktor eksternal pelayanan makanan yang mempengaruhi kepuasan pasien. Metode penelitian ini  menggunakan survei cross sectional dengan jumlah responden 40 orang. Analisis univariat karakteristik responden didapatkan umur ≥ 35 tahun (52,5%), jenis kelamin perempuan (60%), mayoritas ibu rumah tangga, lama hari rawat terbanyak 4 hari. Analisis Bivariat menunjukan tidak ada hubungan antara Faktor Internal dan Faktor Eksternal Pelayanan Makanan dengan Kepuasan Pasien masing – masing p value = 1,000 (p 0,05). Perlu adanya perbaikan dalam peralatan makan pasien kelas 3 di rumah sakit Budhi Asih.
Hubungan Tingkat Pengetahuan dan Gaya Hidup dengan Kejadian Hipertensi di RW 08 Wilayah Kerja Puskesmas Kampungtengah Kramat Jati
Authors: Dewi Nurma
Published: March 2023

Hipertensi merupakan penyakit kardiovaskuler yang paling umum di derita oleh masyarakat. Seseorang dikatakan hipertensi bila hasil pemeriksaan tekanan darah sistolik â‰¥ 140 mmHg dan diastolik â‰¥ 90 mmHg. Tekanan darah tinggi seringkali disebut â€œsilent killerâ€ karena tidak memiliki tanda dan gejala. Kurangnya pengetahuan dan gaya hidup yang tidak sehat dapat menjadi penyebab terjadinya peningkatan tekanan darah dan dapat menjadi komplikasi penyakit jantung, gagal ginjal dan stroke. Tujuan Penelitian adalah untuk mengetahui hubungan tingkat pengetahuan dan gaya hidup dengan kejadian hipertensi di Puskesmas Kampungtengah Kramat Jati. Metode penelitian menggunakan desain Deskriptif Korelasi dengan pendekatan Cross Sectional Survey. Teknik pengambilan sampel menggunakan purposive sampling dengan jumlah 83 responden. Uji statistika menggunakan uji Chi Square. Hasil penelitian ini adalah terdapat hubungan yang signifikan antara tingkat pengetahuan dengan kejadian hipertensi (p = 0,002), terdapat hubungan yang signifikan antara hubungan gaya hidup dengan kejadian hipertensi (p = 0,000). Direkomendasikan untuk menugaskan tenaga kesehatan terutama perawat dalam memberikan pendidikan kesehatan tentang pengetahuan hipertensi, memperbaiki cara gaya hidup yang baik agar dapat mencegah terjadinya komplikasi. Selain itu dapat meningkatkan program senam hipertensi dan skrining hipertensi untuk pencegahan terjadinya komplikasi.
Edukasi Peran Orangtua dalam Mendukung Kesehatan Siswa Sekolah Dasar Melalui Asupan Gizi yang Optimal
Authors: Simanjorang Chandrayani , Karima Ulya Qoulan , Buntara Arga , Izza Fathia Nurul , Riyantiasis Erlina , Adha Namira
Published: March 2023

Indonesia menjadi salah satu negara dengan permasalahan gizi pada anak Sekolah Dasar. Dengan demikian penerapan gizi seimbang di lingkungan sekolah dasar dapat menjadi salah satu upaya yang sangat penting dalam menurunkan prevalensi masalah gizi di Indonesia. Permasalah mittra (SD Islam Serambi Depok) diantaranya belum tersedianyan kantin sehat dan seringnya siswa tidak konsentrasi saat belajar karena belum sarapan. Oleh karena itu sangat diperlukan peran orangtua siswa terutama Ibu dalam menerapkan gizi seimbang bagi anak-anak mereka. Tujuan dari pengabdian ini adalah melakukan edukasi peran orangtua dalam mendukung kesehatan siswa sekolah dasar melalui asupan gizi seimbang. Metode yang digunakan yaitu ceramah dan diskusi dengan 12 orangtua siswa. Topik edukasi yang diberikan adalah 1) Gizi seimbang anak sekolah, 2) Nasihat dan Penguatan oleh Guru Tentang Gizi Seimbang. Media edukasi yang digunakan adalah materi dalam bentuk power point dan media leaflet. Evaluasi dilakukan pada tahap persiapan, pelaksanaan, dan peningkatan pengetahuan. Hasil menunjukkan bahwa terdapat peningkatan pengetahuan peserta dari rata-rara skor 39,58 menjadi 76,04. Dibutuhkan rencana tindak lanjut dari pihak sekolah dalam pembuatan program sarapan bersama dengan menu seimbang yang melibatkan para orangtua siswa.
Edukasi Gizi Seimbang dan Cegah Anemia Pada Remaja
Authors: Angesti Annisa Nursita , Wijayanti Wiwit , Wandini Kartika , Winarta I Made , Prikhatina Ratih Agustin
Published: March 2023

Remaja merupakan kelompok usia yang mendapatkan perhatian dalam memperbaiki gizi selama periode 1000 HPK. Periode 1000 HPK akan menentukan kualitas hidup generasi selanjutnya sebab dimulai dari masa kehamilan. Defisiensi zat gizi mikro seperti anemia masih menjadi tantangan besar bagi Indonesia mengingat jumlahnya masalahnya meningkat selaama beberapa tahun terakhir. Remaja dengan masalah anemia akan berisiko menjadi ibu hamil yang anemia dan melahirkan bayi anemia, BBLR dan stunting, sehingga masalah anemia akan terus berlanjut ke generasi selanjutnya. Salah satu upaya yang dapat dilakukan adalah dengan meningkatkan kesadaran dan pengetahuan remaja tentang cegah anemia dengan konsumsi makanan sumber zat besi dan makanan bergizi seimbang. Kegiatan edukasi diperlukan untuk menyampaikan informasi agar meningkatkan pengetahuan remaja mengenai anemia melalui kegiatan penyuluhan. Teknik permainan puzzle isi piring makanku dan media audio visual melalui video animasi dipilih agar pesan dapat tersampaikan dengan baik pada remaja, sehingga remaja dapat menerapkan prinsip gizi seimbang dalam kehidupan sehari-hari. Pelaksanaan kegiatan pengabdian masyarakat ini dapat diterima baik oleh remaja dengan adaya peningkatan pengetahuan tentang anemia, antusias serta perhatian selama kegiatan berlangsung.
Sosialisasi Pentingnya Donor Darah dan Dampak Anemia Bagi Kesehatan Reproduksi Wanita Pada Siswi di SMA Negeri 48 Jakarta
Authors: Fatimah Sundari , Utami Febi Puji
Published: March 2023

Darah adalah salah satu komponen sangat penting dalam tubuh manusia. Memilih untuk mendonorkan darah dapat menyelamatkan banyak nyawa. Bukan hanya memberikan keuntungan bagi penerima darah, pendonor juga mendapatkan manfaat seperti membantu membuang lebihnya zat besi yang ada dalam tubuh. Zat besi yang sangat lebih dalam darah akan mengoksidasi kolesterol. Hasil proses oksidatif akan menumpuk di dinding arteri sehingga meningkatkan terjadinya serangan jantung dan stroke. Selain itu penting untuk diketahui dampak anemia bagi kesehatan reproduksi wanita, karena anemia berhubungan dengan masa menstruasi yang dialami, namun karena tidak diimbangi dengan pola makan dan gizi seimbang. Faktor penyebab anemia pada remaja putri antara lain gayaÂ hidup seperti pola makan, lauk pauk,Â dan kurang menyukai sayur. Tujuan utama untuk memberikan sosialisasi kepadaÂ siswi di sekolah menengah atas mengenai pentingnya donor darah dan dampak anemia bagi kesehatan reproduksi wanita. Selain upaya pemerintah, harus adanya peran aktif orang tua dalam memberikanÂ gizi seimbang kepada anak-anaknya.Â Idealnya setiapÂ orang butuh zat gizi 20 mg/hari, namun nyatanya rata-rataÂ asupan makananÂ hanya 5,4 mg/hari. Kegiatan diawali dengan penjajakan lokasi dan pengurusan ijin serta waktu pelaksanaan dengan mitra. Kegiatan dilakukan di SMA N 48 Jakarta dan diikuti oleh 38 siswi. Bentuk pengabdian yang diberikan berupa: (1) Sosialisasi pentingnya donor darah, (2) Sosialisasi dampak anemia bagi kesehatan reproduksi wanita, dan (3) Pemberian materi gizi (makanan sehat dan tablet tambah darah). MelaluiÂ sosialisasi ini diharapkan permasalahanÂ anemia padaÂ remaja putri dapat dicegah sejak dini.Â Hasil kegiatan pengabdian kepada masyarakat ini dapat dijadikan acuan dalam meningkatkan program kesehatan masyarakat dan kesehatan reproduksi wanita.Â Kata Kunci : Sosialisasi, Donor Darah, Anemia, Kesehatan Reproduksi.
A review of immediate drug release dosage forms
Authors: B Dhanakishore , M V Jhansi Priya , Narapusetty Naidu
Published: March 2023

Tablets are currently the most widely used dosage form due to their ease of self-administration, compactness, and simple production. In many situations, rapid action is necessary rather than conventional therapy. Immediate release dosage forms have become an alternative to traditional oral dose forms in order to address these shortcomings. Immediately after administration, immediate medication release dose forms dissolve more quickly. Super disintegrants such carboxymethylcellulose (Croscarmellose), sodium starch glycolate (Primogel, Explotab), cross-linked polyvinylpyrrolidone (Polyplasdone), and others are employed as the fundamental method in the manufacture of tablets. After being administered to the stomach, these powerful disintegrants instantly dissolve tablets. In this area, parenteral dosage forms and instant release liquid dosage forms have both been introduced for the treatment of patients. It is possible to administer suspensions in liquid dose form using common dispersion agents as hydroxypropyl methylcellulose, AOT (dioctyl sulfosuccinate), etc. Many medications, including neuroleptics, cardiovascular medications, analgesics, antihistamines, and other medications, can be thought of as candidates for this dose form as a result of the advent of immediate release therapy. Pharmaceutical companies frequently create a certain medication entity in a new and improved dosage form as the drug entity's patent life is about to expire. While providing its patient group with a more practical dosage form or dosing schedule, a new dosage form enables a producer to extend market exclusivity.
Valley development and Quaternary tectonics in the Hlučínská pahorkatina (hilly land)
Authors: Czudek Tadeáš
Published: March 2023

The author describes delis, dry valleys, river valleys, cryopediments as well as valley asymmetry in the area consisting of Pleistocene deposits. Special attention is devoted to the role of Quaternary tectonics in valley development. Hlučínská pahorkatina (hilly land) is situated in the region near the Czechoslovak-Polish frontier (North-West from Ostrava, North Moravia, Czechoslovakia).
Coriolis Force and Baer Law
Authors: Loyda Ludvík , Podracký Pavel
Published: March 2023

According to the Baer law - often applied in geomorphology - what we call the Coriolis force causes the shifting of water flows regardless of their speed and direction. The author pays attention to the fact that many geomorphological phenomena remain quantitatively unexplained (with the aid of modern mathemathical-physical methods). On many examples he shows that in comparison with other agents (wind, oscillations of the streamline, tectonics) the Coriolis force is very small to be of any importance.
Comparative study of machine learning methods in the task of diagnostics of synchronous electric motors
Authors: Дюк В.А. , Каминский В.Ю.
Published: March 2023

Экспериментально подтверждена эффективность современных инструментов машинного обучения для решения задачи бессенсорной диагностики синхронных электродвигателей. Многие из представленных методов продемонстрировали способность строить высокоточные модели в рамках сформулированной задачи. Важным в проведенном анализе являются преимущества примененной предобработки электрических сигналов с помощью метода эмпирической модовой декомпозиции. Эта предобработка во многом обусловила высокие показатели диагностических моделей. Сравнительное исследование различных инструментов машинного обучения показало, что наиболее точные результаты продемонстрировали методы: деревьев решений, случайного леса и ближайших соседей (точность диагностики более 99,78%). Вместе с тем, при использовании тех или иных методов следует учитывать, что несмотря на высокие результаты метода ближайших соседей для его реализации потребовалось почти в 100 раз больше временных ресурсов. С другой стороны, хотя методы деревьев решений и случайного леса построили модели примерно одинаковой точности, модель случайного леса оказалась на два порядка более ресурсоемкой при её формировании и на порядок более ресурсоемкой при её использовании.

The effectiveness of modern machine learning tools for solving the problem of sensorless diagnostics of synchronous electric motors has been experimentally confirmed. Many of the presented methods have demonstrated the ability to build high-precision models within the framework of the formulated task. Important in the analysis are the advantages of the applied preprocessing of electrical signals using the method of empirical mode decomposition. This preprocessing largely caused the high performance of diagnostic models. A comparative study of various machine learning tools showed that the most accurate results were demonstrated by the methods of: decision trees, random forest and nearest neighbors (diagnostic accuracy is more than 99.78%). At the same time, when using certain methods, it should be borne in mind that despite the high results of the nearest neighbors method, its implementation required almost 100 times more time resources. On the other hand, although the methods of decision trees and random forest built models with approximately the same accuracy, the random forest model turned out to be two orders of magnitude more resource-intensive when it was formed and more than an order of magnitude more resource-intensive when it was used.
Scheme of building a computational experiment for calculating climatic and ionospheric parameters of the Earth
Authors: Колин А.Д. , Медведев В.В.
Published: March 2023

В данной работе представлена математическая модель расчета высотно-временных параметров нейтрального и ионного состава, скоростей, температуры, описываемая системой дифференциальных уравнений с не самосопряжённым дифференциальным оператором. Таким образом целью данной работы является правильное написание системы дифференциальных уравнений, описывающих мезосферу, термосферу и ионосферу, а также метод их решения и проверку правильности полученных результатов, что и составляет валидация, верификация, идентификация. В результате проведенных исследований, для этих уравнений, путем свертки написана однородная, консервативная, разностная схема, численно устойчивая удовлетворяющая принципу максимума, построенная на основе интегро-интерполяционного метода, которая решается методом прогонки. Была написана блок-схема численного решения этих уравнений, которая существенно облегчает понимание всей структуры такой модели и позволяет проводить вычислительный эксперимент для любого пользователя.

This paper presents a mathematical model for calculating the height-time parameters of the neutral and ionic composition, velocities, temperature, described by a system of differential equations with a non-self-adjoint differential operator. Thus, the purpose of this work is the correct writing of a system of differential equations describing the mesosphere, thermosphere and ionosphere, as well as a method for solving them and checking the correctness of the results obtained, which is validation, verification, identification. As a result of the research, for these equations, by convolution, a homogeneous, conservative, difference scheme was written, numerically stable satisfying the maximum principle, built on the basis of the integro-interpolation method, which is solved by the sweep method. A block diagram for the numerical solution of these equations was written, which greatly facilitates the understanding of the entire structure of such a model and makes it possible to conduct a computational experiment for any user.
Industrial Yeast Characterisation for Single Cell Protein Application
Authors: De-Barros Maria Clara , Bizerra-Santos Júlia , Maia Luanna , Ribeiro-Filho Normando
Published: March 2023

Food waste and protein for food and feed are among the worldwide concerns. For years, yeast cells have been used for food production; and lately, have been applied for protein enrichment and for food recovery. Breweries, wineries, and distilleries generate a large amount of yeasts that are mostly wasted. Moreover, food loss that includes fruit waste is also a world concern, therefore, identifying the characteristics of yeast cells to drive its application to the correct source can be useful for reducing fruit waste and yeast waste. Therefore, this work aimed to evaluate the potential of yeast strains used by breweries, wineries, and distilleries for future application as single cell proteins including food waste recovery, sustainable food processing, protein for vegetarian products, or world's protein necessities. Two Saccharomyces cerevisiae (NCYC2592 and M2), and one Saccharomyces pastorianus (W34/70) were evaluated by using traditional and modern methods for evaluating four tests including permissive growth temperature, capacity to grow on different carbon sources, DNA fingerprint (physiological differentiation), and mineral content. NCYC2592 can grow at 40 °C. W34/70 can grow on melibiose and rhamnose; NCYC2592 and M2 could not grow on these carbohydrates. P, K and Mg are the most abundant minerals present in all strains. Yeasts that contain higher concentration of macro-minerals such as P, K, and Mg can grow under higher temperatures.
Celebrity and the Cultural Nation.Thomas Mann’s Lotte in Weimar
Authors: Piel Maryann
Published: March 2023

Abstract Mann’s 1939 Goethe novel, Lotte in Weimar, is a valuable text through which to understand the role of celebrity in the literary and political landscape of the early 20th century. I explore the ways in which an engagement with the field of Celebrity Studies
makes possible a reading of Mann’s Goethe as a palimpsest of the historical celebrity author, Mann, a 20th century celebrity author, and Hitler, Germany’s most famous politician in the media age. Mann’s own experiences in the spotlight, especially those gathered in his exile
years, inform the social and familial relationships at the center of the novel. Furthermore, Mann takes an ironic stance towards the “Goethe Mythos,” thereby undermining the validity of the cult of genius and inviting a reading that recognizes its shared features with the cult
of modern celebrity that made possible Hitler’s rise to power.
Der Zauberer im Netz.Literatur und Leben in der brasilianischen Rezeption des Zauberberg
Authors: Soethe Paulo
Published: March 2023

Abstract Der Beitrag befasst sich mit der neueren Rezeption von Thomas Manns Der Zauberberg in seinem ,Mutterland‘ Brasilien. Der familiengeschichtliche Hintergrund wird kurz dargelegt, aktuelle Daten zur Zirkulation und Rezeption der brasilianischen Übersetzung
des Romans in der Neuausgabe von 2016 werden besprochen. Der Sichtbarmachung von individuellen Leseerfahrungen und der Entstehung literarischer Diskurse in den Sozialnetzwerken schenkt der Text besondere Aufmerksamkeit: Das Beispiel aus Brasilien macht erstens deutlich, dass der mittlerweile
hundert Jahre alt werdende Roman von Thomas Mann gerade jetzt unter vielen, auch jüngeren Leserinnen und Lesern großen Anklang findet, und zweitens, dass durch Digitalisierung und neue Herangehensweisen wie die Netnography auch zum Werk des ,Zauberers‘ ein neues, ergiebiges
Areal der international und interdisziplinär ausgerichteten Forschung entsteht.
Selbstprüfung. Versuch über Thomas Mann und eine vergessene politische Tugend
Authors: Blaumer Nikolai
Published: March 2023

Abstract Seit seiner Hinwendung zur Demokratie kultivierte Thomas Mann eine politische Tugend, die gerade für einen Intellektuellen seiner Generation alles andere als selbstverständlich war. Er scheute sich nicht, sein eigenes Denken fortwährend kritisch zu
prüfen und Positionen auch öffentlich zu korrigieren. Jene bemerkenswerte Qualität Thomas Manns ist lange übersehen worden. Sie sollte gerade angesichts der politischen ,Zeitenwende‘ unserer Tage Vorbild sein.
Method Validation for Determination of Paracetamol in Tablet Dosage Form Using UV-Visible Spectrophotometer
Authors: Ben-Hander Gazala Mohamed
Published: March 2023

A simple, accurate, and cost-effective UV-spectrophotometric method for determining Paracetamol in tablet pharmaceutical formulations has been developed. The method was designed and validated in accordance with the criteria of the International Conference on Harmonization (ICH). The developed method was validated statistically concerning linearity range, precision, accuracy, the limit of detection and the limit of quantitation. The study used ethanol-water as a solvent, and λmax was found to be 243 nm. In the range of 2.0–16.0 µg mL-1, a pure drug concentration was prepared, and linear regression analysis revealed a good linear connection with an R2 value of 0.999. The detection and quantification limits were determined to be 0.5 and 1.5 µg mL-1, respectively. The recoveries ranged between 103 and 109%, and the relative standard deviation was less than 2%, indicating that this method was developed for the potential determination of Paracetamol in tablet dosage formulations.
Scintillators for Precision y-Spectrometers
Authors: Belousov Maksim , Ignat'ev Oleg
Published: March 2023

The article analyzes the possibilities of using modern scintillators that provide a relative energy resolution along the y-line of 137Cs ER662keV ≤ 5%. Precision gamma spectrometers are relevant for use in technological processes of the nuclear industry, at nuclear power plants for monitoring the activity of air, waste water and adjacent areas, etc. Now 36 scintillation crystals are known that meet the above mentioned requirement. Of these, only 8 are produced by industry. Seven crystals are candidates for development in industrial production. The rest are hardly suitable for practical use due to the low light yield of LY (Cs2NaGdCl6:Ce, Tl2LiYCl6:Ce and TlCaCl3, for example). Eu-activated crystals have a high light output (LY = 60÷100 ph/MeV) and a low light output nonlinearity (NLY = 7÷10%) in a wide range of electron energies, which is extremely important for the spectrometry of “soft” y-radiation (ER662keV ≤ 10%). Due to the high self-absorption of light, these scintillators lose their advantages in the energy range Ey = 200÷3000 keV. The article shows that among the scintillators suitable for the simultaneous detection of gamma and neutron radiation, crystals containing 6Li are more preferable.
Legal Case Method applied to the film "Judgment at Nuremberg"
Authors: Manzanero Delia
Published: March 2023

The aim of this paper is to reflect and comment on certain scenes from Stanley Kramer’s film Judgment at Nuremberg based in the Case Method methodology used in university lessons to teach Law and Ethics. The judgement which this film addresses is extraordinary, being one in which judges themselves were judged by other judges; as such, it presents a perfect example through which to think about the social responsibility of the legal profession with respect to the application of Law and what relationship this has to broader moral and ethical considerations of the value of human rights.
SCREENING AND TRADING PROCEDURES IN THE SHARIA CAPITAL MARKET
Authors: Lubis Ihsan Helmi
Published: March 2023

Sharia capital market is an activity concerned with public offerings and trading of securities, public companies related to securities issued, as well as institutions and professions related to securities that are run on the basis of sharia principles. This is certainly not separated from the screening procedures that must be passed to get into the Jakarta Islamic Indexs (JII). This means not all types of shares can enter in JII. The purpose of this screening is to fulfill the principle that an investor only transactions (trading) on something kosher or not contrary to Islamic Sharia. This paper will try to expose the screening procedure until trading in the sharia capital market.
To what extent was the exposure risk of COVID-19 amongst the healthcare workers in Mumbai from March 2021-October 2021?
Authors: Anand Gauravv
Published: March 2023

The world witnessed an epidemic and healthcare workers played a vital role. They played a key role in providing essential health services and distributing COVID-19 vaccines along with balancing the additional service requirements. In their endeavors to protect the larger group, they ran a higher chance of being infected and were subjected to various dangers, including psychological discomfort, exhaustion, stigma, and many others. Also, the data related to healthcare workers and the risks of taking care of patients is insufficient. Hence, it is imperative to examine and study elevated risk because of COVID-19 among healthcare workers to avert further spread. The author of this paper attempts to study the correlation of exposure risk with infection while treating the patient. A detailed study was conducted to assess the risks associated with getting exposed to COVID-19 among healthcare workers in Mumbai city and data were collected through a questionnaire that was framed for collating information on socio-demographic factors as well as exposure-related. The assessment of the risk related to disease because of exposure was done and the data was examined using the SPSS tool.A total of 209 healthcare workers were studied, out of which 16 (7.6%) tested positive for COVID-19. The result states that the factors related to exposure had no correlation to patients who tested positive. While in the risk category, the high exposure was showing strong relation with a positive test of COVID-19. The respondents with risk of high category were more frequent to get infected. It was needed to educate and train them at different levels in the hospitals to find out standard practices in order to prevent COVID-19 among healthcare providers. Along with that, designing appropriate preventive measures to reduce the exposure risk at all levels among healthcare sectors also a must.
Study of injuries epidemiological charasteristics in Georgia on the example of Adjara region
Authors: SUKNIDZE Mariam , PITSKHELAURI Nato , CHIKHLADZE Nino
Published: March 2023

Introduction. Injury is a significant public health concern that is a leading cause of mortality and disability worldwide. Injuries have a significant financial and quality-of-life impact on persons and communities. The absence of fundamental epidemiological data on the prevalence of injuries prevents developing countries from creating effective prevention programs. The goal of this study was to characterise the epidemiological features of injury in the Adjara region. Material and methods. The database and source of the data that we used in this article were provided from the Georgian National Center for Disease Control and Public Health’s 2019 database, which contains all hospitalizations in the Adjara area and was utilized to find trauma cases that were treated at medical facilities. Based on the ICD-10 diagnosis codes S and T, as well as V-Y, cases were chosen. Version 23.0 of SPSS was used to analyze the data. Results. Between the ages of 0 and 103, there were a total number of 2,239 patients, inclusive 1,321 (59%) – males, and 918 (41%) – women, who were hospitalized for treatment of an injury. The incidence was highest among those aged 65 and over (n=510; 23%), followed by those aged 20-34 (n= 488; 20%). The most prevalent cause of injury was falling (n=1,324; 59%), followed by exposure to inanimate mechanical forces (n=244; 11%). The range of hospital stays was from 1 to 3,652 days, with a median and mode of 3 and 2 days. Conclusions. This study provides information for public health decision-making. In order to enhance the standard of treatment and focus efforts on avoiding more injuries, intervention strategies may be devised using our data to understand better the extent of the injuries and outcomes linked to traumatic injury hospitalizations.
Parents' knowledge, attitudes and practices regarding household injury of children under 5 years old
Authors: CAZACU-STRATU Angela , COCIU Svetlana , PLAMADEALA Alexandru , COMAN Madalina
Published: March 2023

Introduction. Around 950,000 children and teenagers die each year as a result of injuries and violence throughout the world. The most common cause of death for children under the age of five is trauma that occurs in the home environment.  Aim of the study: To assess the knowledge, attitudes and practices of parents with children aged 0-5 years old regarding unintentional injuries among home environment. Materials and methods. Parents of children under five years old were asked to complete a survey between October and December 2021, which was distributed online via social media. The questionnaire contained 43 items and was analysed using Microsoft Excel. Results. The questionnaire was completed by 300 parents with children up to 5 years old, mostly aged between 26-35 years old (72%), with high education (79.3%), of them 96% females, majority from urban areas (79.7%), with medium socio-economic status. Nearly 75% of respondents believe their child could get hurt at home, most commonly through an injury (42.7%), followed by ingesting foreign objects (22%). Falls were the primary cause of the majority of the child's accidents over the last year (60%) despite them being uncommon (54.7%) and infrequent (22%) in nature. Most often (54.7%), parents said that they see and hear their child all the time, but occasionally leave them for a short time. When their child suffered an injury at home, only 33.3% of parents sought medical attention. Conclusion. The results of this study will allow for a greater focus on young children's safety in the household. By identifying and emphasizing the knowledge, attitudes, and practices of parents with children 0–5 years old, we will be able to notify the necessary authorities and advise particular measures to prevent home accidents.
A tűzoltósági, katasztrófavédelmi légzésvédelem története, jelene és jövőbeli lehetőségei
Authors: Pántya Péter
Published: March 2023

Aim: Intervention activities in fire and disaster management areas typically take place in a damaged environment that is hazardous to occupants. The composition, pollution and oxygen content of the air, which has a direct impact on the tactics, methods and personnel conditions of intervention, can be a major source of danger during firefighting, technical rescue or disaster relief operations. There was no significant difference in these damage conditions in the recent (last decades) and more distant (‘hundred years’) past, however this is a very under-researched and under-publicised area. If necessary and possible, the air at the scene of the damage has always had to be isolated from the fire-fighting forces, as centuries of research have shown. The aim of this article is to explore the past in this aspect and to summarise the available Hungarian and international literature. Compressed air respiratory protection is mainly applicated in the fire service field, hence the focus of this article too. The general firefighting environment, the contingency at the scene of the fire, and the circumstances of interventions requiring respiratory protection are described. This will be followed by a review of the more distant and then more recent past solutions, describing the historical and, as they have evolved, the current national and international technical environment in the field of respiratory protection.Methodology: In the article, the current research results of national and international authors in the field under study and the scarcity of available research were analysed by using literature search.Findings: The research and this publication will review the past solutions and historical developments in firefighter respiratory protection that have led to the capabilities used nowadays.Value: This summarizing work can be considered as a niche work, especially few researches and writings in Hungarian language deal with the field of firefighting, the early possibilities of respiratory protection.