bluuebunny/crossref_metadata_2025 huggingface dataset:
Superparamagnetic Copper Ferrite Nanoparticles as an Efficient Heterogeneous Catalyst for the α‐Arylation of 1,3‐Diketones with CC Cleavage
Authors: Nguyen Anh T. , Nguyen Lan T. M. , Nguyen Chung K. , Truong Thanh , Phan Nam T. S.
Published: February 2014

Superparamagnetic CuFe2O4 nanoparticles were synthesized from CuCl2 and FeCl3 by a co‐precipitation method in ethylene glycol and characterized by several techniques, which included vibrating sample magnetometry, XRD, SEM, TEM, atomic absorption spectrometry, and nitrogen physisorption measurements. The CuFe2O4 nanoparticles could be used as a solid catalyst for the α‐arylation reaction of acetylacetone with iodobenzene to form phenylacetone as the principal product and 3‐phenyl‐2,4‐pentanedione as the byproduct. The reaction that used the CuFe2O4 nanoparticles as catalyst could proceed to completion with 95 % selectivity to phenylacetone. The CuFe2O4 nanoparticles could be separated easily from the reaction mixture by magnetic decantation and could be reused several times for the α‐arylation reaction without a significant degradation in catalytic activity.
The Role of Ru and RuO2 in the Catalytic Transfer Hydrogenation of 5‐Hydroxymethylfurfural for the Production of 2,5‐Dimethylfuran
Authors: Jae Jungho , Zheng Weiqing , Karim Ayman M. , Guo Wei , Lobo Raul F. , Vlachos Dionisios G.
Published: February 2014

We have previously shown that 2,5‐dimethylfuran (DMF) can be produced selectively from 5‐hydroxymethylfurfural in up to 80 % yield via catalytic transfer hydrogenation with 2‐propanol as a hydrogen donor and Ru/C as a catalyst. Herein, we investigate the active phase of the Ru/C catalyst by using extended X‐ray absorption fine structure, X‐ray photoelectron spectroscopy, and high‐resolution TEM analyses. The results reveal that RuO2 is the dominant phase in the fresh (active) catalyst and is reduced to metallic Ru during the reaction with the hydrogen produced in situ from 2‐propanol. The deactivation of the catalyst is correlated with the reduction of the surface of RuO2. Reactivity studies of individual phases (bulk RuO2 and reduced Ru/C catalysts) indicate that RuO2 mainly catalyzes the Meerwein–Ponndorf–Verley reaction of 5‐hydroxymethylfurfural that produces 2,5‐bis(hydroxymethyl)furan and the etherification of 2,5‐bis(hydroxymethyl)furan or other intermediates with 2‐propanol and that the reduced Ru/C catalyst has moderate hydrogenolysis activity for the production of DMF (30 % selectivity) and other intermediates (20 %). In contrast, a physical mixture of the two phases increases the DMF selectivity up to 70 %, which suggests that both metallic Ru and RuO2 are active phases for the selective production of DMF. The oxidation of the reduced Ru/C catalyst at different temperatures and the in situ hydrogen titration of the oxidized Ru/C catalysts were performed to quantify the bifunctional role of Ru and RuO2 phases. The mild oxidation treatment of the Ru/C catalyst at 403 K could activate the catalyst for the selective production of DMF in up to 72 % yield by generating a partially oxidized Ru catalyst.
A Mechanistic Study of Ni‐catalyzed Carbon Dioxide Coupling with Ethylene towards the Manufacture of Acrylic Acid
Authors: Yang Gang , Schäffner Benjamin , Blug Matthias , Hensen Emiel J. M. , Pidko Evgeny A.
Published: February 2014

The reaction mechanism of CO2 coupling with C2H4 by homogeneous Ni‐complexes bearing bidentate phosphorous ligands was studied by means of density functional theory calculations. The reaction is initiated by sequential coordination of C2H4 and CO2 to the Ni center, followed by a facile coupling step, which results in a stable nickelalactone intermediate. Subsequent decomposition of this intermediate through β‐H transfer is the rate‐determining step. Together with the following reductive elimination step to form acrylic acid they represent a strongly kinetically‐hampered process. Destabilization of the nickelalactone intermediate in the presence of large bite angle bidentate ligands has only a minor effect on the overall reaction energetics. Modifying the electronic properties of ligands is also not effective to drive the reaction in a catalytic manner. These studies indicate that the coupling reaction has to be enforced through an alternative route. It is predicted here that a base‐assisted decomposition of the nickelalactone intermediate represents a favorable reaction channel. The factors affecting the reactivity of this route are investigated. The best reactivity corresponds to the CH3OH‐solvated CH3ONa that allows the β‐H transfer step to proceed with a barrier of only 49 kJ mol−1.
[(NHC)Fe(CO)4] Efficient Pre‐catalyst for Selective Hydroboration of Alkenes
Authors: Zheng Jianxia , Sortais Jean‐Baptiste , Darcel Christophe
Published: February 2014

[(IMes)Fe(CO)4] [IMes=1,3‐bis(2,4,6‐trimethylphenyl) imidazol‐2‐ylidene] complex was found to be an efficient pre‐catalyst for the hydroboration of functional alkenes in the presence of pinacolborane at room temperature. Notably, UV irradiation (350 nm) is important to promote this catalytic transformation. Interestingly, high chemo‐ and regioselectivities were observed as only anti‐Markovnikov boronate derivatives were obtained and various functional groups can be tolerated.
Electrochemical Recognition of Selective Lead Adsorption on O2‐Plasma‐Treated Carbon Nanotubes
Authors: Wei Yan , Yang Ran , Liu Jin‐Huai , Huang Xing‐Jiu
Published: February 2014

Lead(II) is a highly toxic contaminant in the environment, and its removal in aqueous solution is generally governed by sorption processes on both organic and inorganic nanomaterials. In this work, an electrochemical method is developed for direct monitoring of the selective adsorption of lead(II) to surface hydroxyl groups of O2‐plasma‐treated carbon nanotubes. After accumulation of lead(II) from aqueous solutions at the open circuit potential, square‐wave anodic stripping voltammetry is performed by immersing an O2‐plasma‐treated carbon‐nanotube‐modified electrode into a detection cell containing 0.1 M NaAc–HAc solution. The process includes desorbing and measuring the amount of previously adsorbed lead(II). Overall, lead(II) adsorption is studied as a function of both the concentration of lead(II) and the pH value.
Triazole‐Tailored Guanosine Dinucleosides as Biomimetic Ion Channels to Modulate Transmembrane Potential
Authors: Kumar Y. Pavan , Das Rabindra Nath , Kumar Sonu , Schütte Ole Mathis , Steinem Claudia , Dash Jyotirmayee
Published: February 2014

A “click” ion channel platform has been established by employing a clickable guanosine azide or alkyne with covalent spacers. The resulting guanosine derivatives modulated the traffic of ions across the phospholipid bilayer, exhibiting a variation in conductance spanning three orders of magnitude (pS to nS). Förster resonance energy transfer studies of the dansyl fluorophore with the membrane binding fluorophore Nile red revealed that the dansyl fluorophore is deeply embedded in the phospholipid bilayer. Complementary cytosine can inhibit the conductance of the supramolecular guanosine channels in the phospholipid bilayers.
ChemInform Abstract: Reactions of Lanthanide Atoms with Oxygen Difluoride and the Role of the Ln Oxidation State.
Authors: Mikulas Tanya , Chen Mingyang , Dixon David A. , Peterson Kirk A. , Gong Yu , Andrews Lester
Published: February 2014

Oxidative addition products OLnF2 (Ln: lanthanide) and OLnF are obtained by condensation of laser‐ablated Ln atoms with OF2 in excess argon or neon at 4 K.
ChemInform Abstract: Doping the Alkali Atom: An Effective Strategy to Improve the Electronic and Nonlinear Optical Properties of the Inorganic Al12N12 Nanocage.
Authors: Niu Min , Yu Guangtao , Yang Guanghui , Chen Wei , Zhao Xingang , Huang Xuri
Published: February 2014

Alkali metal doped M@Al12N12 (M: Li, Na, K) nanocages are characterized by B3LYP/6‐31+G(d), MP2 and QCISD ab initio computations.
ChemInform Abstract: Site‐Preference Among Three Anions in the Quaternary BaAl4‐Type Structure: Experimental and Computational Investigations for BaLi1.09(1)In0.91Ge2.
Authors: Nam Gnu , Jang Eunyoung , You Tae‐Soo
Published: February 2014

BaLi1.09In0.91Ge2 is synthesized from a mixture of Ba, Li, In, and Ge in a ratio of 1:2:2:2 (Nb tube, 950 °C, 5 h) and characterized by single crystal XRD and TB‐LMTO‐ASA quantum chemical calculations.
ChemInform Abstract: Polar Alignment of Λ‐Shaped Basic Building Units within Transition Metal Oxide Fluoride Materials.
Authors: Poeppelmeier Kenneth R. , et al. et al.
Published: February 2014

A series of compounds K10(M2OnF11‐n)3X (M: V, Nb, n = 2, X: (F2Cl)1/3, Br, Br4/2I4/2; M: Mo, n = 4, X: Cl, Br4/2, I4/2) is hydrothermally synthesized from aqueous mixtures of KX (X: F, Cl, Br, I), M2O5 (M: V, Nb) or MoO3, and HF (autoclave, 150 °C, 24 h).
ChemInform Abstract: Citric Acid‐Assisted Phase Controlled Synthesis of NaYF4:Yb3+,Tm3+ Crystals and Their Intense Ultraviolet Upconversion Emissions.
Authors: Jiang Tao , Qin Weiping , Zhou Jun
Published: February 2014

The title compound is hydrothermally synthesized from aqueous solutions containing Ln(NO3)3 (Ln: Y, Yb, Tm), citric acid, and NaF (autoclave, 180 °C, 12 h).
ChemInform Abstract: Preparation and Luminescent Properties of Cubic Potassium—Erbium Fluoride Nanoparticles.
Authors: Bartunek Vilem , Rak Jakub , Pelankova Barbora , Sofer Zdenek , Ulbrich Pavel , Kuchar Martin , Kral Vladimir
Published: February 2014

Cubic KErF4 nanoparticles are prepared from mixtures of Er(NO3)3, KCl, and [bmim]PF6 (PFA tube, 200 °C, 5 h), with [bmim]PF6 acting as both solvent and fluorine source.
ChemInform Abstract: Effect of Local Structure Distortion on Superconductivity in Mg‐ and F‐Codoped LaOBiS2.
Authors: Chen Haijie , Zhang Ganghua , Hu Tao , Mu Gang , Li Wei , Huang Fuqiang , Xie Xiaoming , Jiang Mianheng
Published: February 2014

Polycrystalline samples of La1‐xMgxO1‐2xF2xBiS2 (x = 0.1—0.35) are prepared by solid state reactions of stoichiometric mixtures of La2O3, La2S3, Bi2S3, BiF3, MgF2, LaF3, MgO, S, and Bi (evacuated quartz tube, 1073 K, 10 h).
ChemInform Abstract: Synthesis, Characterization, and Electronic Structure of Single‐Crystal SnS, Sn2S3, and SnS2.
Authors: Burton Lee A. , Colombara Diego , Abellon Ruben D. , Grozema Ferdinand C. , Peter Laurence M. , Savenije Tom J. , Dennler Gilles , Walsh Aron
Published: February 2014

Single crystals of SnS (I), SnS2 (II), and Sn2S3 (III) are grown by chemical vapor transport using stoichiometric amounts of Sn and S and I2 as transport agent (evacuated silica ampule, 950→850 °C for (I), 850→600 °C for (II), and 650→500 °C for (III)).
ChemInform Abstract: Cationic Disorder and Mn3+/Mn4+ Charge Ordering in the B′ and B′′ Sites of Ca3Mn2NbO9 Perovskite: A Comparison with Ca3Mn2WO9.
Authors: Lopez C. A. , Saleta M. E. , Pedregosa J. C. , Sanchez R. D. , Alonso J. A. , Fernandez‐Diaz M. T.
Published: February 2014

Polycrystalline Ca3MnIII2WO9 (I) and Ca3MnIII/IV2NbO9 (II) are prepared by calcination in air of stoichiometric mixtures of CaCO3, MnCO3, and WO3 (or Nb2O5) (Pt crucible, 800 °C, 12 h).
ChemInform Abstract: Transition‐Metal‐Doped Zinc Oxide Nanoparticles as a New Lithium‐Ion Anode Material.
Authors: Bresser Dominic , Mueller Franziska , Fiedler Martin , Krueger Steffen , Kloepsch Richard , Baither Dietmar , Winter Martin , Paillard Elie , Passerini Stefano
Published: February 2014

Zn0.9Fe0.1O (I) and Zn0.9Co0.1O (II) nanoparticles are prepared from their respective aqueous gluconate hydrates in a sucrose solution followed by H2O evaporation, drying at 300 °C, and calcination in air (450 °C, 3 h).
ChemInform Abstract: Reversible CO2 Absorption by the 6H Perovskite Ba4Sb2O9.
Authors: Dunstan Matthew T. , Liu Wen , Pavan Adriano F. , Kimpton Justin A. , Ling Chris D. , Scott Stuart A. , Dennis John S. , Grey Clare P.
Published: February 2014

Polycrystalline Ba4Sb2O9 is prepared by calcination of a stoichiometric mixture of BaCO3 and Sb2O3 (1273 K, 2 d).
ChemInform Abstract: Electrochemical Synthesis of a Lithium‐Rich Rock‐Salt‐Type Oxide Li5W2O7 with Reversible Deintercalation Properties.
Authors: Pralong Valerie , Venkatesh Gopal , Malo Sylvie , Caignaert Vincent , Baies Radu , Raveau Bernard
Published: February 2014

The title compound is synthesized by electrochemical lithium intercalation into Li2W2O7, which is obtained by solid state reaction of stoichiometric mixtures of Li2CO3 and WO3 (500 °C, 24 h).
ChemInform Abstract: Synthesis, Crystal Structure, and Properties of Sodium Heptafluorodiantimonate(III) Hydrate (NaSb2F7·H2O).
Authors: Zemnukhova L. A. , Udovenko A. A. , Makarenko N. V. , Fedorishcheva G. A. , Kavun V. Ya. , Slobodyuk A. B. , Didenko N. A.
Published: February 2014

The new title compound is obtained from an aqueous solution of NaSCN and SbF3 in a molar ratio of 1:2 (Pt crucible, slow crystallization at room temperature).
ChemInform Abstract: Preparation and Photoluminescence of Green‐Emitting Phosphors SrGa2S4: Eu.
Authors: Na Sang‐Hee , Cho Young‐Sik , Do Young Rag , Huh Young‐Duk
Published: February 2014

The photoluminescent properties of the title phosphor as a green emitting candidate for phosphor‐converted three‐band white LEDs are examined.
ChemInform Abstract: Hydrothermal Synthesis of LaCO3OH and Ln3+ ‐Doped LaCO3OH Powders under Ambient Pressure and Their Transformation to La2O2CO3 and La2O3.
Authors: Lee Min‐Ho , Jung Woo‐Sik
Published: February 2014

LaCO3OH powders are prepared from mixtures of La(NO3)3 and urea dissolved in a mixture of ethylene glycol and water (reflux, 24 h).
ChemInform Abstract: Ba3TM2Se9 (TM: Nb, Ta): Synthesis and Characterization of New Polyselenides.
Authors: Chung Ming‐Yan , Lee Chi‐Shen
Published: February 2014

Ba3Nb2Se9 (I) and Ba3Ta2Se9 (II) are prepared by solid state reactions of stoichiometric mixtures of the elements (evacuated silica tubes, 1023 K, 1 d).
ChemInform Abstract: Synthesis and Crystal Structures of (pyH)2[Mo2O4F6] and (pipH2)[Mo2O4F6]; Vibrational Band Assignment for [Mo2O4F6]2‐ Anion.
Authors: Veryasov Gleb , Morozov Dmitry , Goreshnik Evgeny , Jesih Adolf
Published: February 2014

Compounds (II) and (IV) are characterized by single crystal XRD and Raman spectroscopy.
ChemInform Abstract: Ferroelectric Transition in the Inorganic Supramolecular Complex (Hg6P4)(CuCl3)2.
Authors: Jiang Xiao‐Ming , Yan Zhi‐Bo , Liu Dan , Wang Jing‐Xue , Liu Mei‐Feng , Guo Guo‐Cong , Jin Biao‐Bing , Li Xiao‐Guang , Liu Jun‐Ming
Published: February 2014

Red single crystals of the new title compound are prepared by stoichiometric solid state reaction of Hg2Cl2, red P, and Cu (evacuated Pyrex tube, 1.
ChemInform Abstract: Asymmetric Diels—Alder Cycloadditions of D‐Erythrose 1,3‐Butadienes to Achiral t‐Butyl 2H‐Azirine 3‐Carboxylate.
Authors: Duarte Vera C. M. , Faustino Helio , Alves Maria J. , Fortes Antonio Gil , Micaelo Nuno
Published: February 2014

The Diels—Alder reaction of D‐erythrose derived 1,3‐butadienes (II) with tert‐butyl 2H‐aziridine 3‐carboxylate, generated in situ by from azide (I), is described.
ChemInform Abstract: Synthesis of Nitrogenated Heterocycles by Asymmetric Transfer Hydrogenation of N‐(tert‐Butylsulfinyl)haloimines.
Authors: Pablo Oscar , Guijarro David , Yus Miguel
Published: February 2014

It provides a simple and efficient method to prepare aziridines, pyrrolidines, piperidines, and azepines with high optical purity.
ChemInform Abstract: Allene Relay: Palladium‐Catalyzed Bicyclization of Allene‐Propargylic Carbonates with Geminal Bis(nucleophile)s.
Authors: Ye Juntao , Ma Shengming
Published: February 2014

An efficient synthesis of fused hetero‐ and carbocycles is presented using the Pd‐catalyzed coupling of allene‐propargylic carbonates with geminal bis‐nucleophiles such as malonoesters, malononitrile, and β‐ketoesters.
ChemInform Abstract: Wittig Reagents as Metallocarbene Precursors: In situ Generated Monocarbonyl Iodonium Ylides.
Authors: Ho Phyllis E. , Tao Jason , Murphy Graham K.
Published: February 2014

A proof of concept study to determine the suitability of iodonium ylide is presented.
ChemInform Abstract: In situ Generation of Diimide from Hydrazine and Oxygen: Continuous‐Flow Transfer Hydrogenation of Olefins.
Authors: Pieber Bartholomaeus , Martinez Teixeira Sabrina , Cantillo David , Kappe C. Oliver
Published: February 2014

The presented catalyst‐free procedure is applicable to several internal and terminal alkenes with high conversions and yields.
ChemInform Abstract: Regio‐ and Stereoselectivity in the Concatenated Enyne Cross Metathesis—Metallotropic [1,3]‐Shift of Terminal 1,3‐Diyne.
Authors: Wang Kung‐Pern , Cho Eun Jin , Yun Sang Young , Rhee Jee Young , Lee Daesung
Published: February 2014

Enyne cross metathesis of terminal 1,3‐diynes with various alkenes affords two product types of distinctive connectivity, as the result of a uniform mode of initiation but different modes of termination events with or without metallotropic [1,3]‐shift.
ChemInform Abstract: Steric Control of Site Selectivity in the Pd‐Catalyzed C—H Acetoxylation of Simple Arenes.
Authors: Cook Amanda K. , Emmert Marion H. , Sanford Melanie S.
Published: February 2014

Pd‐catalyzed oxidative acetoxylation of benzenes is studied using hypervalent iodine acetates.
ChemInform Abstract: Catalytic Fluorination of 1,3‐Dicarbonyl Compounds Using Iodoarene Catalysts.
Authors: Kitamura Tsugio , Muta Kazutaka , Kuriki Satoshi
Published: February 2014

Optimized reaction conditions are developed for the fluorination of 1,3‐dicarbonyl compounds by using aqueous hydrofluoric acid, iodoarene as catalyst, and MCPBA as terminal oxidant.
ChemInform Abstract: Chemoselective Carbozincation of Cyclopropene for C—C Bond Formation and Cleavage in a Single Operation.
Authors: Endo Kohei , Nakano Takeo , Fujinami Shuhei , Ukaji Yutaka
Published: February 2014

The title reaction sequence gives highly functionalized and sterically congested alkylamines.
ChemInform Abstract: 3‐Chloro‐1‐lithiopropene, a Functional Organolithium Reagent, and Its Reactions with Alkylboronates to Give 3‐Alkylprop‐1‐en‐3‐ols.
Authors: Smith Keith , Elliott Mark C. , Jones D. Heulyn
Published: February 2014

Treating 1‐bromo‐3‐chloropropene (II) with tBuLi leads to the formation of unstable 3‐chloro‐1‐lithiopropene which is trapped in situ by alkylboronic esters.
ChemInform Abstract: Multifaceted Catalysis Approach to Nitrile Activation: Direct Synthesis of Halogenated Allyl Amides from Allylic Alcohols.
Authors: Lester Roy P. , Dunsford Jay J. , Camp Jason E.
Published: February 2014

Title compounds (III) and (V) are synthesized from the reaction of allylic alcohols (I) and halogenated nitriles (II) and (IV), respectively.
ChemInform Abstract: Formation of 2‐Halomethylene‐4‐cyclopentene‐1,3‐diones and/or 2‐Halo‐1,4‐benzoquinones via Ring‐Expansion of 4‐Ethynyl‐4‐hydroxy‐2,3‐substituted‐2‐cyclobuten‐1‐ones. Total Synthesis of Methyl Linderone.
Authors: Yin Hong , Dantale Shubhada W. , Akhmedov Novruz G. , Soederberg Bjoern C. G.
Published: February 2014

The synthetic value of the present ring‐expansion protocol is demonstrated by a short total synthesis of methyl linderone (XI).
ChemInform Abstract: Construction of Enantioenriched Cyclic Compounds by Asymmetric Allylic Alkylation and Ring‐Closing Metathesis.
Authors: Giacomina Francesca , Alexakis Alexandre
Published: February 2014

In some cases the two step procedure is performed in one pot without quenching the reaction mixture after the allylic alkylation step before the Grubbs catalyst is added.
ChemInform Abstract: The Cope Rearrangement of gem‐Dimethyl Substituted Divinylcyclopropanes.
Authors: Osler Jonathan D. , Unsworth William P. , Taylor Richard J. K.
Published: February 2014

The rate‐retarding effect of gem‐dimethyl substitution on the Cope rearrangements of divinylcyclopropanes is demonstrated for the first time.
ChemInform Abstract: Cross‐Coupling Reaction of a Highly Strained Molecule: Synthesis of σ—π Conjugated Tetrahedranes.
Authors: Kobayashi Yuzuru , Nakamoto Masaaki , Inagaki Yusuke , Sekiguchi Akira
Published: February 2014

Reaction of tetrakis(trimethylsilyl)tetrahedrane with MeLi produces a solution of tris(trimethylsilyl)tetrahydryl lithium which is easily amenable for Pd‐catalyzed cross‐coupling processes to produce thermally stable arylated tetrahedranes.
ChemInform Abstract: Selective Direct Heterocoupling of Alkenes Catalyzed by in situ Generated Ruthenium Complexes.
Authors: Simon Marc‐Olivier , Darses Sylvain
Published: February 2014

This method yields the exo‐(E) products with excellent selectivity from bicyclic alkenes and Michael acceptors.
ChemInform Abstract: Palladium‐Catalyzed Methylation of Alkynyl C(sp)—H Bonds with Dimethyl Sulfonium Ylides.
Authors: Liu Yan‐Yun , Yang Xu‐Heng , Huang Xiao‐Cheng , Wei Wen‐Ting , Song Ren‐Jie , Li Jin‐Heng
Published: February 2014

Various different functionalized alkynes can be methylated through a C(sp)—C(sp3) bond formation process.
ChemInform Abstract: Rhodium(III)‐Catalyzed Intermolecular N‐Chelator‐Directed Aromatic C—H Amidation with Amides.
Authors: Zhao Huaiqing , Shang Yaping , Su Weiping
Published: February 2014

Rh‐catalyzed direct C‐H bond amidation is achieved with different N‐heterocycles as directing groups and tosylamides and trifluoroacetamide as coupling partners.
ChemInform Abstract: Formation of 2‐(Phenylsulfonyl)resorcinols (= 2‐(Phenylsulfonyl)benzene‐1,3‐diols) from Symmetrically Substituted Maleic Anhydrides (= Furan‐2,5‐diones).
Authors: Abou‐Hadeed Khaled , Hansen Hans‐Juergen
Published: February 2014

Treatment of cyclopentene‐1,3‐diones (V) with lithium (phenylsulfonyl)methanide (II) and with excess amounts of BuLi leads to the formation of benzene‐1,3‐diols (VI).
ChemInform Abstract: Copper‐Catalyzed Enantioselective Henry Reaction of Enals and Subsequent Iodocyclization: Stereoselective Construction of Chiral Azatricyclic Frameworks.
Authors: Zhou Yirong , Zhu Yuequan , Yan Shaobai , Gong Yuefa
Published: February 2014

The presented method gives access to a broad scope of functionalized β‐nitro allylic alcohols in high yields and enantioselectivities from cyclic and acyclic enals.
ChemInform Abstract: Asymmetric Ring Opening of meso‐Epoxides with Aromatic Amines Using (R)‐(+)‐BINOL‐Sc(OTf)3‐NMM Complex as an Efficient Catalyst.
Authors: More Ganesh V. , Bhanage Bhalchandra M.
Published: February 2014

Inexpensive and simple starting materials are used for the in situ generation of the highly efficient title complex.
ChemInform Abstract: Selective Hydroformylation—Acetalization of Various Olefins Using Simple and Efficient Rh‐Phosphinite Complex Catalyst.
Authors: Khan Shoeb R. , Bhanage Bhalchandra M.
Published: February 2014

The reaction does not require any acid co‐catalysts and tolerates aromatic and aliphatic alkenes.
ChemInform Abstract: Aerobic Oxidation of Aldehydes by Visible Light Photocatalysis.
Authors: Iqbal Naeem , Choi Sungkyu , You Youngmin , Cho Eun Jin
Published: February 2014

A highly efficient photolytic oxidation of aliphatic and aromatic aldehydes to the corresponding carboxylic acids is developed using molecular oxygen as oxidant and a fluorinated iridium complex as photocatalyst.
ChemInform Abstract: Pd‐Catalyzed Alkynylation of 2‐Chloroacetates and 2‐Chloroacetamides with Potassium Alkynyltrifluoroborates.
Authors: Molander Gary A. , Traister Kaitlin M.
Published: February 2014

A protocol is developed to allow the coupling of N‐substituted chloroacetamides and analogous esters with alkynyltrifluoroborates to give β,γ‐alkynyl amides and esters in good yields.
ChemInform Abstract: Carbon—Sulfur Bond Formation Catalyzed by [Pd(IPr*OMe)(cin)Cl] (cin = cinnamyl).
Authors: Bastug Gulluzar , Nolan Steven P.
Published: February 2014

The Pd complex (PIC) is found to be an efficient catalyst for the coupling of aryl halides with thiols.
ChemInform Abstract: S‐, N‐, and Se‐Difluoromethylation Using Sodium Chlorodifluoroacetate.
Authors: Mehta Vaibhav P. , Greaney Michael F.
Published: February 2014

A cost‐effective protocol for the decarboxylative difluoromethylation of aromatic and heteroaromatic thiols is developed using sodium chlorodifluoroacetate as reaction component.
ChemInform Abstract: Stereoselective Formation of Z‐ or E‐Vinyl Thioethers from Arylthiols and Acetylenes under Transition‐Metal‐Free Conditions.
Authors: Liao Yunfeng , Chen Shanping , Jiang Pengcheng , Qi Hongrui , Deng Guo‐Jun
Published: February 2014

An efficient anti‐Markovnikov hydrothiolation of acetylenes with arylthiols is reported.
ChemInform Abstract: Iron Halide‐Mediated Regio‐ and Stereoselective Halosulfonylation of Terminal Alkynes with Sulfonylhydrazides: Synthesis of (E)‐β‐Chloro and Bromo Vinylsulfones.
Authors: Li Xiaoqing , Shi Xinhua , Fang Mingwu , Xu Xiangsheng
Published: February 2014

Halosulfonylation of terminal alkynes is achieved with sulfonylhydrazides as the sulfonyl precursor and iron halide as halide source in the presence of TBHP, allowing the regio‐ and stereoselective generation of (E)‐β‐chloro and bromo vinylsulfones.
ChemInform Abstract: Arylation of Lithium Sulfinates with Diaryliodonium Salts. A Direct and Versatile Access to Arylsulfones.
Authors: Umierski Natalie , Manolikakes Georg
Published: February 2014

An efficient, transition‐metal‐free arylation of lithium sulfinates, obtained from reactions of the corresponding organolithium reagents with sulfur dioxide, is described.
ChemInform Abstract: Difluoro(sulfinato)methylation of N‐Sulfinyl Imines Facilitated by 2‐Pyridyl Sulfone: Stereoselective Synthesis of Difluorinated β‐Amino Sulfonic Acids and Peptidosulfonamides.
Authors: Prakash G. K. Surya , Ni Chuanfa , Wang Fang , Zhang Zhe , Haiges Ralf , Olah George A.
Published: February 2014

Fluoroalkylation of chiral imines (I) using 2‐pyridyl‐SO2‐CF2H as masked difluoro(sulfinato)methylation reagent is developed resulting in a highly stereoselective synthesis of optically active α,α‐difluoro‐β‐amino sulfones.
ChemInform Abstract: Pd‐Catalyzed Direct Arylation of Nitro(pentafluorosulfanyl)benzenes with Aryl Bromides.
Authors: Wang Chao , Yu Yan‐Bo , Fan Shilu , Zhang Xingang
Published: February 2014

A facile access to SF5‐containing aryl derivatives is developed using a Pd‐catalyzed direct C‐H arylation reaction of the corresponding SF5‐substituted nitrobenzenes.
ChemInform Abstract: Palladium‐Catalyzed Desulfitative Cross‐Coupling of Sodium Arylsulfinates with Aryl Bromides and Chlorides: An Alternative Convenient Synthesis of Biaryls.
Authors: Zhou Chao , Li Yaming , Lu Yang , Zhang Rong , Jin Kun , Fu Xinmei , Duan Chunying
Published: February 2014

The title reaction proceeds under relatively mild reaction conditions without the need for additives, base or co‐catalyst.
ChemInform Abstract: Phosphine‐Catalyzed Domino Benzannulation: An Efficient Method to Construct Biaryl Skeletons.
Authors: Zheng Jie , Huang You , Li Zhengming
Published: February 2014

The phosphine‐catalyzed reaction of dienic sulfones with allenoates is developed to synthesize a variety of functionalized biaryls.
ChemInform Abstract: Pd(0)‐Catalyzed 1,1‐Diarylation of Ethylene and Allylic Carbonates.
Authors: Saini Vaneet , Liao Longyan , Wang Qiaofeng , Jana Ranjan , Sigman Matthew S.
Published: February 2014

1,1‐Diarylalkenes are easily synthesized from a mixture of aryldiazonium tetrafluoroborates, arylboronic acids and olefins such as ethylene or allylic carbonates via a one‐step procedure.
ChemInform Abstract: Room‐Temperature Bismuth‐Catalyzed Bis‐arylation of Carbonyl Compounds with Aryl Ethers and Phenols.
Authors: Liu Congrong , Li Manbo
Published: February 2014

The combined use of the Lewis acid catalyst and TmsCl at room temperature gives access to a wide range of bis‐ and triarylmethanes in good to excellent yields.
ChemInform Abstract: Pd‐Catalyzed Semmler—Wolff Reactions for the Conversion of Substituted Cyclohexenone Oximes to Primary Anilines.
Authors: Hong Wan Pyo , Iosub Andrei V. , Stahl Shannon S.
Published: February 2014

A synthesis of primary anilines and 1‐aminonaphthalenes via a modified Semmler—Wolff reaction is presented.
ChemInform Abstract: Chiral N‐Fluorodibenzenesulfonimide Analogues for Enantioselective Electrophilic Fluorination and Oxidative Fluorination.
Authors: Zhu Chuan‐Le , Maeno Mayaka , Zhang Fa‐Guang , Shigehiro Taiki , Kagawa Takumi , Kawada Kosuke , Shibata Norio , Ma Jun‐An , Cahard Dominique
Published: February 2014

The electrophilic fluorination is demonstrated on the compounds (I), (III), and (V).
ChemInform Abstract: Synthesis of Phenanthrenes by Cationic Chromium(III) Porphyrin‐Catalyzed Dehydration Cycloaromatization.
Authors: Wakabayashi Ryota , Kurahashi Takuya , Matsubara Seijiro
Published: February 2014

The dehydrative cycloaromatization of biphenyloxirans to give a variety of phenanthrene derivatives by using a readily available cationic chromium porphyrine complex as catalyst is described.
ChemInform Abstract: Synthesis of Highly Substituted Hexahelicenes
Authors: Schwertel Manfred , Hillmann Sabine , Meier Herbert
Published: February 2014

synthesis of C2‐symmetric hexahelicenes with four or six alkoxy chains
ChemInform Abstract: Synthesis of Benzannulated Spiroacetals Using Chiral Gold—Phosphine Complexes and Chiral Anions.
Authors: Quach Rachelle , Furkert Daniel P. , Brimble Margaret A.
Published: February 2014

The asymmetric cyclization of the diol (I) with respect to the enantioselectivity of the formation of the spiroacetal (III) is investigated.
ChemInform Abstract: Fused Spirocyclic Imidazolone Ketals.
Authors: Arduengo Anthony J. III , Gurau Gabriela , Kelley Steven P. , Marshall William J. , Runyon Jason W.
Published: February 2014

Mild oxidation of zwitterionic azolium alkoxides (I) and (III) under anhydrous conditions leads to new stable spirocyclic ketals (II) and (IV).
ChemInform Abstract: Activation of Hydrogen Peroxide by Diphenyl Diselenide for Highly Enantioselective Oxaziridinium Salt Mediated Catalytic Asymmetric Epoxidation.
Authors: Buckley Benjamin , Elliott Claire E. , Chan Yohan , Dreyfus Nicholas , Page Philip C. Bulman
Published: February 2014

Perselenic acid, generated in situ from diphenyl diselenide and hydrogen peroxide, is demonstrated to be a useful oxidant for the transformation of trisubstituted ethylene derivatives to epoxides.
ChemInform Abstract: One‐Step Preparation of O‐(α‐Bromoacyl) Cyanohydrins by Minor Enantiomer Recycling: Synthesis of 4‐Amino‐2(5H)‐furanones.
Authors: Hertzberg Robin , Moberg Christina
Published: February 2014

Coupling of cyanides of type (I) with various aldehydes using a one‐step recycling procedure allows formation of (α‐bromoacyl) cyanohydrins in good yields with high diastereoselectivity.
ChemInform Abstract: Phosphine Catalyst‐Controlled Cycloaddition or Dienylation Reactions of Trifluoromethyl Aryl Ketones with Bis‐substituted Allenoates.
Authors: Xiao Hua , Chai Zhuo , Yao Ri‐Sheng , Zhao Gang
Published: February 2014

Depending on the used phosphine organocatalyst, the reaction of activated ketones (I) and allenoates (II) yields either tertiary dienols or furan derivatives with quaternary stereocenters.
ChemInform Abstract: One‐Pot Synthesis of Substituted Benzo[b]furans from Mono‐ and Dichlorophenols Using Palladium Catalysts Bearing Dihydroxyterphenylphosphine.
Authors: Yamaguchi Miyuki , Katsumata Haruka , Manabe Kei
Published: February 2014

It is found that the phosphine (DHP) efficiently promotes the Pd‐catalyzed reaction of 2‐chlorophenols with terminal alkynes.
ChemInform Abstract: Diastereo‐ and Enantioselective Three‐Component Coupling Approach to Highly Substituted Pyrrolidines.
Authors: Chaulagain Mani Raj , Felten Albert E. , Gilbert Kevin , Aron Zachary D.
Published: February 2014

The enantioselective synthesis of substituted pyrrolidines through a mild Lewis‐acid catalyzed three‐component coupling reaction between amino acids, heteroaromatic aldehydes, and olefins is reported.
ChemInform Abstract: A Novel Tandem Sequence to Pyrrole Syntheses by 5‐endo‐dig Cyclization of 1,3‐Enynes with Amines.
Authors: Bharathiraja Ganesan , Sakthivel Sekarpandi , Sengoden Mani , Punniyamurthy Tharmalingam
Published: February 2014

A new approach to highly substituted pyrroles by using 1,3‐enynes and primary amines in the presence of excess iodine is developed.
ChemInform Abstract: Chiral Scandium(III)‐Catalyzed Enantioselective α‐Arylation of N‐Unprotected 3‐Substituted Oxindoles with Diaryliodonium Salts.
Authors: Guo Jing , Dong Shunxi , Zhang Yulong , Kuang Yulong , Liu Xiaohua , Lin Lili , Feng Xiaoming
Published: February 2014

The scalable method is applicable to a broad range of arylated oxindoles and diaryliodonium salts with high to excellent enantioselectivity.
ChemInform Abstract: Construction of Functionalized Spiro 1,4‐Benzoxazine Oxindole Derivatives via Domino Mannich‐Alkylation of α‐Halocarbonyl Compounds with Imines.
Authors: Huang Xiao , Zhang Ya‐Ru , Li Xin‐Sheng , Xu Dong‐Cheng , Xie Jian‐Wu
Published: February 2014

The reaction proceeds under mild conditions and allows the preparation of the title compounds on a gram scale.
ChemInform Abstract: Ruthenium‐Catalyzed Regioselective C2 Alkenylation of Indoles and Pyrroles via C—H Bond Functionalization.
Authors: Li Bin , Ma Jianfeng , Xie Weijia , Song Haibin , Xu Shansheng , Wang Baiquan
Published: February 2014

Under these new conditions a wide range of 2‐alkenylated indoles and pyrroles as well as 2,5‐dialkenylated pyrroles are available.
ChemInform Abstract: Controlling the Molecular Topology of Vinylogous Iminium Ions by Logical Substrate Design: Highly Regio‐ and Stereoselective Aminocatalytic 1,6‐Addition to Linear 2,4‐Dienals.
Authors: Silvi Mattia , Chatterjee Indranil , Liu Yiankai , Melchiorre Paolo
Published: February 2014

A novel diphenylprolinol catalyzed vinylogous cascade reaction of 3‐hydroxy‐2‐oxindoles (I) with dienals (II) is developed to produce spirooxindoles through an asymmetric 1,6‐1,4 sequential addition.
ChemInform Abstract: Urea Activation of Nitrimines: A Mild, Metal‐Free Approach to Sterically Hindered Enamines.
Authors: Nickerson David M. , Angeles Veronica V. , Mattson Anita E.
Published: February 2014

N‐Nitrosubstituted imines react with a wide range of secondary amines in the presence of an urea catalyst to give different sterically encumbered enamines under mild and metal‐free conditions.
ChemInform Abstract: Synthesis of a Potential Intermediate for TMC‐95A via an Organocatalyzed Aldol Reaction.
Authors: Pearson Anthony J. , Panda Santanu , Bunge Scott D.
Published: February 2014

This describes the synthesis of pseudopeptide organocatalysts and their application in the asymmetric aldol reaction to yield compounds (III).
ChemInform Abstract: Gold‐Catalyzed Cascade C—C and C—N Bond Formation: Synthesis of Polysubstituted Indolequinones and Pyrroles.
Authors: Abdukader Ablimit , Xue Qicai , Lin Aijun , Zhang Ming , Cheng Yixiang , Zhu Chengjian
Published: February 2014

Au/Ag‐catalyzed condensation of 2‐bromonaphthoquinone or nitrostyrenes with enaminones provides an efficient synthesis of the title compounds (III) or (VI).
ChemInform Abstract: Enantioselective Synthesis of Angularly Substituted 1‐Azabicyclic Rings: Coupled Dynamic Kinetic Epimerization and Chirality Transfer.
Authors: Aron Zachary D. , Ito Tatsuya , May Tircia L. , Overman Larry E. , Wang Jocelyn
Published: February 2014

This method starts from substrates with high enantiomeric excesses and proceeds with excellent chirality transfers (usually ≥ 96%) yielding products with up to three stereocenters.
ChemInform Abstract: Synthesis of Benzotrifuran and Benzotripyrrole Derivatives and Molecular Orientations on the Surface and in the Solid State.
Authors: Tsuji Hayato , Cantagrel Guillaume , Ueda Yasuyuki , Chen Ting , Wan Li‐Jun , Nakamura Eiichi
Published: February 2014

An interesting synthesis of 2,5,8‐trisubstituted benzotrisfurans and analogous benzotrispyrroles is developed using the base promoted reaction of triethynyltrifluorobenzenes (I) and (III) with water or primary amines.
ChemInform Abstract: Catalyst Free Michael Addition of 3‐Methyl‐2‐pyrazolin‐5‐one to β‐Nitrostyrenes “on Water”: A Green Protocol for Facile Synthesis of 4‐(1‐Aryl‐2‐nitroethyl)‐3‐methyl‐1H‐pyrazol‐5‐ol.
Authors: Meshram H. M. , Kumar Nadigama Satish , Nanubolu Jagadeesh Babu , Rao L. Chandrasekhara , Rao N. Nageswara
Published: February 2014

The reaction is conducted under environmentally benign conditions.
ChemInform Abstract: Synthesis and Tautomerism of Substituted Pyrazolo[4,3‐c]pyrazoles.
Authors: Kadam Shivaji S. , Maier Lukas , Kostakis Ioannis , Pouli Nicole , Tousek Jaromir , Necas Marek , Marakos Panagiotis , Marek Radek
Published: February 2014

The spectroscopic data for all isomers [(III)‐(V)] and [(VII)‐(IX)] are interpreted by DFT methods.
ChemInform Abstract: Synthesis of Substituted 5‐Bromomethyl‐4‐nitroimidazoles and Use for the Preparation of the Hypoxia‐Selective Multikinase Inhibitor SN29966.
Authors: Lu Guo‐Liang , Ashoorzadeh Amir , Anderson Robert F. , Patterson Adam V. , Smaill Jeff B.
Published: February 2014

Various synthetic methods leading to 5‐(bromomethyl)‐4‐nitroimidazoles are described.
ChemInform Abstract: One‐Pot Synthesis of Isoxazoles from Enaminones: An Application of Fe(II) as the Catalyst for Ring Expansion of 2H‐Azirine Intermediates.
Authors: Zheng Yunhui , Yang Chao , Zhang‐Negrerie Daisy , Du Yunfei , Zhao Kang
Published: February 2014

A direct one‐pot method for the synthesis of isoxazoles from enaminones (I) is described through their PIDA‐promoted cyclization to azirines followed by a previously reported FeCl2‐catalyzed rearrangement.
ChemInform Abstract: Supported Protic Acid‐Catalyzed Synthesis of 2,3‐Disubstituted Thiazolidin‐4‐ones: Enhancement of the Catalytic Potential of Protic Acid by Adsorption on Solid Supports.
Authors: Kumar Dinesh , Sonawane Mukesh , Pujala Brahmam , Jain Varun K. , Bhagat Srikant , Chakraborti Asit K.
Published: February 2014

The reaction does not require any additional reagent and the products are easy to isolate.
ChemInform Abstract: Anodic Mediated Synthesis and Antifungal Study of Bis‐1,3,4‐oxadiazoles.
Authors: Sharma L. K. , Saraswat A. , Singh S. , Siddiqui I. R. , Kehari H. K. , Singh R. K. P.
Published: February 2014

New bis‐1,3,4‐oxadiazoles (IIb)—(IId) show efficient antifungal activity against C.
ChemInform Abstract: Novel Iodine Catalyzed Diastereoselective Synthesis of trans‐2,6‐Disubstituted Tetrahydro‐2H‐pyrans: Synthesis of C1—C13 Fragment of Bistramide‐A.
Authors: Yadav Jhillu Singh , Gyanchander Eppa , Mishra Anand Kumar , Adithya Peddapuram , Das Saibal
Published: February 2014

Trans‐2,6‐substituted 2‐allylated pyrans are stereoselectively prepared by iodine catalyzed allylation of the corresponding tetrahydro‐2H‐pyranols.
ChemInform Abstract: Stereospecific Asymmetric N‐Heterocyclic Carbene (NHC)‐Catalyzed Redox Synthesis of Trifluoromethyl Dihydropyranones and Mechanistic Insights.
Authors: Davies Alyn T. , Taylor James E. , Douglas James , Collett Christopher J. , Morrill Louis C. , Fallan Charlene , Slawin Alexandra M. Z. , Churchill Gwydion , Smith Andrew D.
Published: February 2014

In the presence of the chiral chloride (NHC), α‐aroyloxyaldehydes undergo stereoselective cyclization with (E)‐ and (Z)‐trifluoromethyl enones to afford syn‐ and anti‐dihydropyranones.
ChemInform Abstract: CuCl2‐Catalyzed Regioselective Dehydrogenative C—H Activation: Synthesis of Coumarin, Quinolone, and Naphthalene Based Pyrrolone Derivatives.
Authors: Roy B. , Hazra Somjit , Mondal Biplab , Majumdar K. C.
Published: February 2014

The reaction is carried out under aerobic conditions and proceeds mostly regioselectively to afford the fused coumarin, quinolone and naphthalene heterocycles.
ChemInform Abstract: Sulfoxide‐Directed Enantioselective Synthesis of Functionalized Tetrahydropyridines.
Authors: Fernandez de la Pradilla Roberto , Simal Carmen , Bates Robert H. , Viso Alma , Infantes Lourdes
Published: February 2014

The highly selective base‐promoted cyclization of enantiopure sulfinyl dienamines provides stereodefined sulfinyl tetrahydropyridines (diastereoselectivity up to 98%).
ChemInform Abstract: Organocatalytic Activation of Alkylacetic Esters as Enolate Precursors to React with α,β‐Unsaturated Imines.
Authors: Hao Lin , Chen Shaojin , Xu Jianfeng , Tiwari Bhoopendra , Fu Zhenqian , Li Tong , Lim Jieyan , Chi Yonggui Robin
Published: February 2014

The first asymmetric organocatalytic activation of simple alkylacetic esters is presented giving products in high yields and with excellent enantioselectivities.
ChemInform Abstract: Applications and Limitations of the I2‐Mediated Carbamate Annulation for the Synthesis of Piperidines: Five‐ versus Six‐Membered Ring Formation.
Authors: Corkran Hilary M. , Munneke Stefan , Dangerfield Emma M. , Stocker Bridget L. , Timmer Mattie S. M.
Published: February 2014

Depending on the substrates ‐ which are derived from carbohydrates ‐ the I2‐mediated cyclization yields either furan or piperidine derivatives.
ChemInform Abstract: Removal of the Pyridine Directing Group from α‐Substituted N‐(Pyridin‐2‐yl)piperidines Obtained via Directed Ru‐Catalyzed sp3 C—H Functionalization.
Authors: Maes Bert U. W. , et al. et al.
Published: February 2014

The authors present two methods for the title transformation.
ChemInform Abstract: Gold‐Catalyzed Cyclization of 3‐(2′‐Azidoaryl)‐1‐arylpropargyl Carbonates or 3‐Aryl‐1‐(2′‐azidoaryl)propargyl Carbonates to Produce Quinolines.
Authors: Zhu Shugao , Wu Luling , Huang Xian
Published: February 2014

The title reactions allow facile access to biologically important quinolines.
ChemInform Abstract: Catalytic sp3 C—H Oxidation of Peptides and Their Analogues by Radical Cation Salts: From Glycine Amides to Quinolines.
Authors: Jia Xiaodong , Wang Yaxin , Peng Fangfang , Huo Congde , Yu Liangliang , Liu Jing , Wang Xicun
Published: February 2014

A catalytic α‐sp3 C—H oxidation of glycine amides and peptides is achieved under radical cation salt catalysis in the presence of oxygen, producing a series of substituted quinolines.
ChemInform Abstract: Regioselective Synthesis of 1,2‐Dihydroquinolines by a Solvent‐Free MgBr2‐Catalyzed Multicomponent Reaction.
Authors: Gutierrez Rsuini U. , Correa Hans C. , Bautista Rafael , Vargas Jose Luis , Jerezano Alberto V. , Delgado Francisco , Tamariz Joaquin
Published: February 2014

The title reaction is catalyzed by magnesium bromide and carried out under solvent‐free conditions.
ChemInform Abstract: 6‐Trifluoromethyl‐phenanthridines Through Radical Trifluoromethylation of Isonitriles.
Authors: Zhang Bo , Mueck‐Lichtenfeld Christian , Daniliuc Constantin Gabriel , Studer Armido
Published: February 2014

A novel synthesis of 6‐perfluoroalkylated phenanthridines is developed using the reaction of biphenyl type isonitriles with Togni reagent (II) and analogs (X).
ChemInform Abstract: [2 + 2 + 2] Cyclotrimerization of Alkynes and Isocyanates/Isothiocyanates Catalyzed by Ruthenium—Alkylidene Complexes.
Authors: Alvarez Silvia , Medina Sandra , Dominguez Gema , Perez‐Castells Javier
Published: February 2014

This method uses established metathesis catalysts for the cyclotrimerization of diynes with isocyanates, isothiocyanates, or carbon disulfide to yield bicyclic heterocyclic products.
ChemInform Abstract: Synthesis of New Substituted 4‐Amino‐3,5‐dinitropyridine Derivatives.
Authors: Ma Congming , Wang Yongbin , Hou Kehui , Liu Zuliang , Yao Qizheng
Published: February 2014

Substrate (I), prepared by nitration of 2‐chloropyridine‐4‐amine, is treated with various reagents to give the corresponding 2‐substituted products.
ChemInform Abstract: Features of Switchable Multicomponent Heterocyclizations of Salicylic Aldehydes and 5‐Aminopyrazoles with Pyruvic Acids and Antimicrobial Activity of the Reaction Products.
Authors: Murlykina Maryna V. , Sakhno Yana I. , Desenko Sergey M. , Konovalova Iryna S. , Shishkin Oleg V. , Sysoiev Dmytro A. , Kornet Maryna N. , Chebanov Valentin A.
Published: February 2014

The three‐component reactions are carried out under thermodynamic control (reflux or microwave heating) and under kinetic control (ultrasonication).
ChemInform Abstract: Highly Enantioselective γ‐Amination by N‐Heterocyclic Carbene Catalyzed [4 + 2] Annulation of Oxidized Enals and Azodicarboxylates.
Authors: Chen Xiang‐Yu , Xia Fei , Cheng Jin‐Tang , Ye Song
Published: February 2014

The title reaction proceeds under mild conditions for a broad substrate scope and from readily available starting materials.
ChemInform Abstract: Ultrasound‐Promoted Efficient Domino Reaction for the One‐Pot Synthesis of Spiro‐5‐cyanopyrimidines: A Rapid Procedure.
Authors: Hussein Essam M.
Published: February 2014

The three‐component one‐pot synthesis of the title compounds gives considerably higher yields with shorter reaction times when conducted under ultrasonic irradiation compared to conventional heating.
ChemInform Abstract: Copper‐Catalyzed Direct Thiolation of Xanthines and Related Heterocycles with Disulfides.
Authors: He Zuying , Luo Fang , Li Yinglong , Zhu Gangguo
Published: February 2014

The title reaction of xanthines and related N‐heterocycles is achieved with Copper acetate as the catalyst and oxygen as a clean oxidant.
ChemInform Abstract: Is the 2,3‐Carbon—Carbon Bond of Indole Really Inert to Oxidative Cleavage by Oxone? — Synthesis of Isatoic Anhydrides from Indoles.
Authors: Nelson Amber C. , Kalinowski Emily S. , Czerniecki Nikolas J. , Jacobson Taylor L. , Grundt Peter
Published: February 2014

Contrary to previous reports, Oxone is found to oxidize indoles (I) via the cleavage of the 2,3‐C—C bond.
ChemInform Abstract: Rearrangement in the Synthesis of Annulated Lactams Starting from Benzothiazines.
Authors: Stalling Timo , Saak Wolfgang , Martens Juergen
Published: February 2014

A novel ring contraction of benzothiazine based methoxyamides is developed using an intramolecular AlCl3‐ or TiCl4‐promoted Friedel—Crafts reaction to give tetracyclic lactams.
ChemInform Abstract: Base‐Catalyzed Diastereoselective [3 + 3] Annulation of 3‐Isothiocyanatooxindoles and Azomethine Imines.
Authors: Zhu Gongming , Su Wangsheng , Wu Chongyang , Li Guofeng , Hong Liang , Wang Rui
Published: February 2014

The unprecedented title reaction is catalyzed by triethylamine affording triazinyl spirooxindoles in high yields and with high diastereoselectivities under mild conditions.
ChemInform Abstract: Facile Synthesis and Coupling of 3,9‐Dibromo‐6‐aryl‐5H‐dibenzo[d,f][1,3]diazepine Derivatives.
Authors: Tomar Manisha , Lucas Nigel T. , Muellen Klaus , Jacob Josemon
Published: February 2014

The title compounds can be further converted via a Suzuki‐coupling to derivatives (V) which are new π‐conjugated organic materials.
ChemInform Abstract: Palladium‐Catalyzed Asymmetric Hydrogenation of Dibenzo[b,f][1,4]thiazepines Activated by Broensted Acid.
Authors: Wang Jinzhu
Published: February 2014

In most cases the use of trifluoroethanol instead of dichloromethane increases the yield, but diminishes the enantioselectivity.
ChemInform Abstract: Regioselective Allene Hydrosilylation Catalyzed by N‐Heterocyclic Carbene Complexes of Nickel and Palladium.
Authors: Miller Zachary D. , Li Wei , Belderrain Tomas R. , Montgomery John
Published: February 2014

Regioselective hydrosilylation of allenes strictly depends on the choice of metal.
ChemInform Abstract: Acid‐Catalyzed Direct Conjugate Alkenylation of α,β‐Unsaturated Ketones.
Authors: Okamoto Kazuhiro , Tamura Eisuke , Ohe Kouichi
Published: February 2014

Treatment of the product (IIIa) with HBF4 gives the compound (IV) via 1,4‐phenyl shift.
ChemInform Abstract: Anchoring of Silyl Donors on a N‐Heterocyclic Carbene Through the Cobalt‐Mediated Silylation of Benzylic C—H Bonds.
Authors: Mo Zhenbo , Liu Yang , Deng Liang
Published: February 2014

Silyl‐donor functionalized NHC‐cobalt complexes are developed and used as catalyst for the hydrosilylation of 1‐octene with PhSiH3 (best catalyst is shown).
ChemInform Abstract: Hetero‐Dehydrocoupling of Silanes and Amines by Heavier Alkaline Earth Catalysis.
Authors: Hill Michael S. , Liptrot David J. , MacDougall Dugald J. , Mahon Mary F. , Robinson Thomas P.
Published: February 2014

The title catalysts are described as efficient pre‐catalysts for the dehydrogenative coupling of arylsilanes with primary and secondary amines.
ChemInform Abstract: Esterification of Five‐Membered Cyclic Phosphinic Acids under Mild Conditions Using Propylphosphonic Anhydride (T3P®).
Authors: Jablonkai Erzsebet , Milen Matyas , Drahos Laszlo , Keglevich Gyoergy
Published: February 2014

The title reaction gives good yields under mild reaction conditions.