bluuebunny/crossref_metadata_2025 huggingface dataset:
İs Combined Acellular Collagen Matrix and High Tibial Osteotomy Treatment Effective In Osteochondral Defects? Preliminary Study
Authors: KONYA Mehmet Nuri , HORATA Erdal , MARALCAN Gökhan , ERTEN Abdullah Recep , TURAMANLAR Ozan
Published: February 2018

Aim:  In this study, we want to compare clinical and
radiological results of 12 patient treated with acellular collagen matrix (ACM)
and High Tibial osteotomy-cellular collagen matrix(ACM-HTO) combination.Method: In this study, we
evaluated 12 patients with chondral lesion prospectively the years of between
2014- 2016 after ethical approval. Cartilage damage was diagnosed with MRI and
cartilage degeneration volume was calculated with Mimics medical image
processing software and axis deviation was diagnosed with ortho X-ray. Patients
were divided into two groups. ACM only (Group 1) and ACM- HTO (Group 2). Results:
 ACM only group consists of 5 patients.
Preoperative mean of chondral lesion volume was 77.11±137.5 (0.27-321.61).
Post-operative mean Knee  score was
175.20±24.4(150-203) and chondral lesion volume was 0.3±0.03(0-0.8). ACM-HTO
group consists of 7 patients. Preoperative mean of chondral lesion volume was
112.72±239(0.27- 653). Post-operative mean of HSS score was 155±20.4(135-183)
and chondral lesion volume was 0.26±0.09(0-0.69).Conclusion: According to these
results, all patients’ HSS scores and Cartilage volume are increased, but there
were no significant differences were found between two groups.
Femur kırıklarının intrameduller çivi ile tedavisinde radyasyon maruziyeti azaltılabilir mi?
Authors: Konya Mehmet Nuri , Kaya Ömer Ali
Published: February 2018

Amaç: Bu  çalışmada, serbest el tekniği ve
elektromanyetik navigasyon sistemi ile distal kilitleme yapılan intramedüller
çivi ameliyatı yapılan olguları, cerrahi süresi ve radyasyon maruziyeti
açısından karşılaştırmayı amaçladık. Yöntem:  Şubat 2012-Şubat 2013 arasında femur kırığı
olan  40 hasta değerlendirildi. Distal
manyetik kilitlemeli İntramedüller Çivileme (DMK+) ve  distal serbest el kilitli intramedüller
çivileme (DMK-) tekniği ile operasyon yapıldı. Distal kilitleme sırasında
kullanılan floroskopi süresi, radyasyon maruziyeti ve cerrahi süresi
karşılaştırıldı. Alınan radyasyon dozu; TC sivil savunma müdürlüğünden temin
edilen NAB 223 marka radyasyon ölçer ile ölçüldü. Bulgular: DMK (-) grubunda 20
femur kırığı mevcuttu.  Distal kilitleme
sırasında ortalama skopi süresi33,7± 12,6 idi, ameliyat süresi 68.50±7.1dk idi.
Radyasyon dozu femur kırığı için 461,7±172,7 idi.  DMK (+) grubunda 20 hastada femur kırığı
mevcuttu. Distal kilitleme sırasında ortalama skopi süresi  29±17,6 idi, 
ameliyat süresi 66.25±10.1 dk. İdi. Radyasyon dozu ise 397,3±241,1 idi. Sonuç: Uzun kemik
kırıklarına uygulanan İntramedüller Çivileme tekniklerini karşılaştırdığımız bu
çalışmada distal manyetik kilitlemeli İntramedüller civilerin alınan skopi
sayısı, ameliyat süresi ve kanama miktarını kilitsiz intramedüller çivilere
göre anlamlı şekilde azaltmadığı gözlenmiştir (p>0.05).
Bilimsel Dergiler Neden Gerekli ?
Authors: Gültekin Fatih
Published: February 2018

Bilimsel Dergiler Neden Gerekli?
Uluslararası Bilimsel Dergi İndeksleri, Önemleri ve Türkiye Kaynaklı Dergilerin Durumu: Bölüm 2: Türkiye’deki Durum
Authors: Asan Ahmet
Published: February 2018

Bu çalışmada, uluslararası bilimsel dergi indekslerinde özellikle
PubMed ve Web of Science kapsamındaki
Türkiye adresli dergilerin güncel listesi, bu dergilerin etki faktörü
değerleri, JCR 2015 dergi sayısı, yayın sayısı ve diğer güncel veriler
sunulmuştur. Bilgiler derlenirken, çeşitli internet sitelerinden,
kitap-dergilerden ve yazarın görüşleri dikkate alınmıştır. Yapılan incelemede,
halen PubMed kapsamında  23, SCI-Expanded
+ SSCI + AHCI kapsamında 66 ve ESCI kapsamında ise 92 Türkiye kaynaklı derginin
olduğu görülmüştür. SCI-Expanded ve SSCI kapsamında Türkiye kaynaklı dergiler
arasında Q1 kategorisinde dergi yoktur, Q2 kategorisinde 2, Q3 kategorisinde 9
ve geriye kalan 49 dergi ise Q4 kategorisindedir.
HUBUNGAN EMOSIONAL DAN SPRITUAL TERHADAP KADAR KORTISOL PERAWAT DI RUMAH SAKIT SULTAN AGUNG SEMARANG
Authors: Sari Rita Kartika
Published: February 2018

ABSTRAK Stresor perawat dapat berasal dari lingkungan kerja seperti beban kerja, suasana kerja, shift kerja, iklim organisasi. Stres yang terjadi terus menerus mempengaruhi kondisi dan fungsi psikoneuroimunologis perawat. Spiritual dipercaya dapat mempengaruhi seseorang untuk meningkatkan kekuatan dan arahan terhadap koping serta pemecahan masalah dalam kehidupan. Penelitian ini bertujuan untuk mengetahui hubungan keadaan emosional dan spritual terhadap keadaan kortisol pada perawat. Desain yang digunakan dalam penelitian adalah cross sectional dengan pendekatan time series design.Sampel sebesar 35 orang. Hasil pengukuran emosional minggu pertama dan ke dua paling besar kesadaran, minggu ke tiga dan empat adalah empati. Keadaan spiritual minggu pertama paling besar kesadaran diri 1.64±0.36, pada minggu ke dua kesadaran diri dan kebenaran 1.64±0.36, pada minggu ke tiga dan ke empat kebenaran 2.49±0.15 dan 2.72±0.14, rerata kadar kortisol pada minggu pertama 181.14±59.52, minggu ke empat 88.43±24.86, keadaan spiritual lebih cenderung dapat menurunkan kadar kortisol dibanding dengan keadaan emosional yang dapat dilihat dari nilai emosional β = -148.54 dengan konstanta 19.50 dan nilai spiritual β = -139 dengan konstanta 47.47,hal ini memberikan interpretasi bahwa peningkatan keadaan emosional satu point dapat menurunkan kortisol -168.04 dan setiap satu point peningkatan spiritual dapat menurunkan kortisol -186.55.Berdasarkan hasil penelitian dapat disimpulkan 1). Terdapat hubungan yang signifikan antara keadaan emosional dan spiritual terhadap kadar kortisol pada perawat di RSI Sultan Agung Semarang. 2). Keadaan emosional dan spiritual dapat menjadi penanda keadaan kortisol pada perawat di RSI Sultan Agung Semarang. Kata kunci: Kortisol, Emosional dan Spiritual, Perawat
POTRET PELAKSANAAN PATIENT SAFETY MAHASISWA PROFESI NERS
Authors: Puspita Sari Dyah Wiji
Published: February 2018

ABSTRAKTerjadinya insideninsiden keselamatan pasien yang disebabkan oleh mahasiswa dapat menimbulkan berbagai efek yang merugikan bagi pasien. Penelitian ini bertujuan untuk mendiskripsikan profil pelaksanaan program keselamatan pasienoleh mahasiswa profesi ners. Penelitian ini melibatkan 36 mahasiswa profesi Ners yang dipilih secara total sampling yang sedang praktik di ruang rawat inap RSISA. Metode dalam penelitian ini adalah diskriptifeksploratif.Berdasarkan hasil analisis data dengan menggunakan distribusi frekuensi menunjukkan bahwa profil pelaksanaan patient safety oleh mahasiswa profesi ners berada dalam kategori sedang. Hasil penelitian ini memiliki implikasi bahwa setiap rumah sakit pendidikan wajib meyakinkan mahasiswa yang akan menjalani praktik klinik untuk paham tentang pelaksanaan program patient safety.Kata kunci:pelaksanaan, keselamatan pasien, mahasiswa profesi ners
TERAPI MUSIK REBANA MAMPU MENURUNKAN TINGKAT STRES PADA LANSIA DI UNIT PELAYANAN SOSIAL PUCANG GADING SEMARANG
Authors: Luthfa Iskim , Khasanah Furaida , Sari Dyah Wiji Puspita
Published: February 2018

ABSTRAKStress yang terjadi pada lansia yang di rawat di Unit Pelayanan Sosial Pucang Gading Semarang disebabkan oleh beberapa hal antara lain, lansia merasa kesepian karena jauh dari keluarga, merasa terasing karena harus tinggal di lingkungan yang baru, mengalami ketergantungan dan ketidakberdayaan. Salah satu terapi untuk menurunkan stress pada lansia yaitu dengan musik tradisional rebana. Terapi musik tradisional rebana menyerupai terapi okupasional yang cara kerjanya mampu menurunkan hormon kortisol yang disebabkan karena stress sehingga tubuh menjadi tenang dan rileks, sehingga seseorang mampu melupakan permasalahannya.Penelitian kuasi eksperimen ini didesain menggunakan pre-test and post-test with control group. Pengambilan sampel menggunakan tekhnik purposive sampling, sampel dalam penelitian sebanyak 20 lansia, yang dibagi menjadi 2 kelompok yaitu 10 lansia kelompok perlakuan dan 10 lansia kelompok kontrol. Untuk kelompok perlakuan diberi intervensi yaitu pemberian terapi musik rebanaselama 30 menit, pemberian terapi musik rebana dilakukan 1 kali seminggu selama 8 minggu. Sedangkan untuk kelompok kontrol tidak diberikan intervensi apapun. Instrument penelitian stress menggunakan skala Holmess dengan 36 pertanyaan.Hasil, Uji independent t test didapatkan pada kelompok perlakuan tingkat stress menurun dari 1,7 menjadi 1,3 (nilai p = 0,037). Untuk kelompok kontrol tingkat stress juga menurun dari 1,3 menjadi 1,2 (nilai p = 0,545), namun penurunan ini dinilai tidak signifikan.Kesimpulannya : Terapi musik rebana mampu menurunkan tingkat stress pada lansia di Unit Pelayanan Sosial Pucang Gading Semarang.Kata kunci : Musik rebana, Stres, Lansia.
THE INFLUENCE OF DHARMAGITA�S ON COGNITIVE FUNCTION IN ELDERLY
Authors: Darma Yanti Ni Putu Emy
Published: February 2018

Cognitive impairment is a condition that negatively impacts the survival of the elderly. Dharmagita is a spiritual song that is one of the sensory stimulation techniques that are good for the elderly. Singing a song may stimulate the release of endorphins and serotonin that can trigger somebody�s thinking and learning. Dharmagita Award is intended to provide sensory stimuli in the elderly so that they can improve the cognitive function of the elderly. This study aimed to determine the effect of Dharmagita on the cognitive function of the elderly. This study was a pre-experimental study with a one-group pretest-posttest design. The sample consisted of 12 elderly people selected by purposive sampling. The data collection was done by using the MMSE questionnaire. The results showed the average scores of the cognitive function before and after Dharmagita, which were 23.92 and 25 respectively. Based on the statistical results using a paired t-test, there were significant differences in cognitive function with the significance level p = 0.001 meaning that there was Dharmagita influence on the cognitive function of the elderly. Therefore, it is recommended to the elderly, caregivers and policy makers to use Dharmagita in improving the cognitive function of the elderly.Keywords: Cognitive function, Dharmagita, Mini Mental Status Examination
KERONCONG MUSIC REDUCES POSTOPERATIVE PAIN IN CRITICAL CARE UNIT
Authors: IDA VITANI RAIMONDA AMAYU
Published: February 2018

Background: Pain that has been experienced by patients in intensive care can lead them into worse condition. The efforts relieving the pain have been done a lot. One of them is to use music therapy. Nevertheless, the researcher has not found the the research of keroncong music therapy as original Indonesian classical traditional music for pain. Purpose: The aims of this study was to know the effect of keroncong music for pain level of the postoperative patients in intensive care. Method: This research used quasy experimental with pre-post nonequivalent control group design on 32 postoperative patients in critical care rooms. Keroncong music therapy has been implemented to the second day postoperative patients, it has been given twice a day and each implementation the patients listened keroncong music for 20 minutes. The pain level was measured using Visual Analogue Scale (VAS). Result: Postoperative pain level in intervention group (22,94 � 14,63) significantly decreased than control group (2,06 � 21,90) with p = 0,003, with a difference of mean 20.88 mm decrease in pain.Conclusion: Keroncong music therapy had effect on the decreasing of pain level of postoperative patients. Keroncong music therapy can be recommended to be independent complementary nursing intervention to decrease the pain level of postoperative patients in intensive care unit.�Keywords: Music therapy; Pain; Postoperative, Keroncong
PORTRAIT OF SELF EFFICACY AND CONSERVATIONMATERNITY NURSING CARE ON PATIENT WITH CERVICAL CANCER
Authors: WURININGSIH APRILIANI YULIANTI
Published: February 2018

Cervical cancer is one of the main chronic diseases in women with a variety of symptoms throughout the patient's life. The adaptation process of the symptoms is an important part which is the responsibility of patients with chronic diseases such as cervical cancer. Conservation and self-efficacy models can assist nurses through a framework based on four principles of conservation that are integrated with all four components of self-efficacy. The integration of these two models can represent the views of individual holistically, active, and independent, and involves the active participation of the patient in the nursing plan. This can help patients to manage a normal life in order to survive and improve their health status.Keywords: cervical cancer, the integration of conservation and self-efficacy theory.
SELF-CONFIDENCE OF NURSES TO TREAT SUDDEN DETERIORATION PATIENTS IN MEDICAL WARDS
Authors: AMAL AHMAD IKHLASUL
Published: February 2018

Background: Sudden deterioration defined as a condition in which a progression over a complex illness. Progression of pain to the patient causing displacement status characterized by the vital signs of patients who experienced abnormality. Nurses in medical and surgical ward almost everytime facing with patients with acute deterioration conditions. Nurses should have confidence when giving proper treatmen for acute patents deterioration. Methods: This study utilize quantitative descriptive research conducted in the hospital ward illness Islam Sultan Agung Semarang. The number of respondents that used in this study were 98 nurses, utilized consecutive sampling technique. Results: The results showed that the average level of confidence gained nurses treating patients in the ward conditions of acute deterioration in the disease is expressed 3.03. It is mean that respondents have moderate level of confidence. Conclusions: The level of confidence of nurses in treating patients with acute exacerbation of conditions needs to be improved to provide excellent service qualityKeywords: nurse, self-confidence, sudden deterioration
IDENTIFICATION OF COMMUNICATION BETWEEN FAMILY AND PRESBYACUSIS PATIENT WHO STAYS IN ONE HOUSE
Authors: AMAL AHMAD IKHLASUL
Published: February 2018

Presbyacusis hearing loss is common in elderly. Patients with presbyacusis may feel neglected by the family and the surrounding environment. It should be takes the right way to communicate with presbyacusis patients, so that communication can be done effectively. This study aims to identify the phenomenon of family communication with presbyacusis patients who stays in one house. Qualitiataive research design was used in this reserch with� phenomenologycal approach. In-depth interviews and observation was used as data collection method. The results of the research found that the family have an understanding about the meaning of communication which is talking alone and talking with others. Family barriers when communicating with presbyacusis patients are difficult to understand what is the family talking about, difficult to talk, disconnected, family feel annoyed and must be patient when communicating. The family communicates with presbyacusis patients using verbal (verbal) communication such as repetition of speech, non-verbal communication (gesture) that is by mouth movement, touching the shoulders, face-to-face when communicating, hand movements. As a conclusion of this research was obtained the understanding of communication, family barriers when communicating with presbiakusis patients, the way families communicate, family reasons using verbal communication (verbal) and non-verbal (cues).Keywords: family communication, presbyacusis, phenomena
The Effect Of Progressive Muscle Relaxation On Sleep Quality In Patients With Hypertension In South Cilacap City
Authors: KASRON KASRON , SUSILAWATI SUSILAWATI
Published: February 2018

Introduction : Patients with hypertension patients can have sleep disorders such as dizziness or headache, feeling tired during the day, anxiety, decreasing concentration and irritability. This study aimed to evaluate the effect of progressive muscle relaxation (PMR) on sleep quality in patients with hypertension in South Cilacap City. Method : The research used quasi-experiment with pre-post test without control group. Respondents werw patients with hypertension in South Cilacap City, with the criteria forthose who were active in health care programme, able to perform independent activities, consume of anti-hypertensive drugs, have done PMR regularly for 7 days, and the exclusion criteria was patients with impaired osteoarthritis and rheumatoid arthritis. Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality twice, before and 7 days after interventions PMR. Statistic analysis used wilcoxon test. 16 respondents included in the criteria. Result : The quality of sleep before treatment PMR was 7 people (43.8%) poor, 9 people (56.3%) very bad. After treatment PMR was 3 people (18.8%) rather good, 13 people (81.3%) less good. The analysis shown the sleep quality was difference between before and after PMR with p-value <0.001. Discussion : The study shows there is difference between before and after PMR in hypertensive patients in South Cilacap. PMR can be used to improve the sleep quality of hypertensive patients.
The Catholic Church and the Evangelisation of 'Nomads' in Italy
Authors: Piasere Leonardo
Published: February 2018

It was only in the 1900s that the Catholic Church began to concern itself systematically with the evangelisation of 'Nomads'. The pastoral strategies did not develop as a monolithic set of actions within the Catholic Church; rather, they varied in relation to specific events and showed considerable diversification. The article discusses this complexity and the interplay between different imageries about the Roma and Sinti and different evangelisation modalities. Eventually, it identifies three active lines which operated within the Catholic Church: the Church of 'projects' for integration, the Church that evangelises, and the Church that 'smells of sheep'. Each line built on different categorisations of Roma and Sinti and proposed different pastoral strategies. The article sums up the history of each line, their evolution and their 'evangelisation imagery' by evoking the actions of three pioneer priests who, as of the 1950s, started pastoral action among Roma and Sinti in Italy.
Romani (Im)Mobility, between Camps, Evictions and Ambivalent Representations of 'Nomads' in the Eternal City
Authors: Solimene Marco
Published: February 2018

This paper explores the trajectories of Bosnian Romani families who migrated to Rome between 1970 and 2000. These families were involved in the Italian and Roman authorities' attempts to govern 'Gypsies/Roma/ Nomads' through different combinations of inclusion and exclusion, and forced to face the radicalisation of xenophobic and anti-Gypsy discourses within Italian society. This paper unravels the complex relations between Romani practices and ideological elaborations of mobility and stability; different and ambiguous ideas of 'Nomads' as constructed and deployed by the Roman authorities; and the consequent sedentarisation and nomadisation processes of the Romani population living in the Eternal City.
Italian Kalderaša between Northern Italy and the Swiss Canton of Ticino. Categorisations, Policies, Everyday Practices
Authors: Bizzini Nadia
Published: February 2018

The article presents the ethnographic case of a group of
Kalderaša
Roma who currently, depending on the time of year, live either side of the border between Italy and Switzerland. Historically, these families have been subject to various categorisations and consequently to different policies that have made them into 'foreign nomads' to be sedentarised in the Swiss territory and into 'ex-nomads' or 'sedentary nomads' without the right to practice nomadism in Italy. The article shows how this group of
Kalderaša
Roma have dealt with the different historical categorisation and policy configurations in both Switzerland and Italy, managing to maintain their own identity and practices as 'peripatetic service nomadic communities'.
The Use of
Zingari/Nomadi/Rom
in Italian Crime Discourse
Authors: Catalano Theresa
Published: February 2018

This study examines the use of the metonymies
zingari/nomadi/rom
[Gypsies/Nomads/Roma] in Italian media discourse, in order to critically reflect on their relation to the perception of Roma. The author analyses the frequency of these terms in general discourse and crime discourse, as well as the way they are used in context. The findings reveal that nomadi and rom are used to directly and indirectly index Roma, and have a significant impact on their ethnicisation and criminalisation. In addition, the episodic framing of crime events, combined with the use of these metonymies, erases the Italian government's responsibility for the conditions of Roma in Italy.
The Seasonal Mobility of Sinti Fairground Workers in the Modena Province
Authors: Secchi Laura
Published: February 2018

This research report sheds light on the scarcely known world of Sinti fairground workers living in the Modena province in Italy's Emilia-Romagna region. The families described herein alternate between a settled life in winter and an itinerant one in summer. In wintertime, they remain in a so-called 'micro-area' situated in the Modena province. In summer, the families that live together during the winter months leave the microarea and spread out following precise itineraries. This report, based on ethnographic fieldwork, reveals the intricate pattern that connects working activities, family ties, spatial strategies and relations with the local authorities.
Le poids économique direct de la culture en 2016
Authors: Picard Tristan
Published: February 2018

En 2016, le poids économique direct de la culture, c’est-à-dire la valeur ajoutée de l’ensemble des branches culturelles, est de 44,5 milliards d’euros. La part de la culture dans l’ensemble de l’économie (2,2 %) est en baisse continue depuis 2003 (2,5 %). La cause principale de cette baisse est la crise structurelle touchant les branches de la presse et du livre (0,6 % du pib en 2003, 0,4 % en 2016). L’année 2016 est marquée par une conjoncture difficile pour les branches du patrimoine et du spectacle vivant (respectivement – 1,2 % et – 1,8 % par rapport à 2015), conséquence directe des attentats de l’année 2015 qui ont eu un impact fort sur le tourisme étranger en Île-de-France et sur les coûts de sécurisation des événements et des équipements culturels. À l’inverse, les arts visuels (+ 3,9 %), l’audiovisuel (+ 2,5 %) et les agences de publicité (+ 2,5 %) poursuivent leur croissance. Représentant 29 % de la valeur ajoutée des branches culturelles, l’audiovisuel est toujours la première branche culturelle en termes de poids économique. En 2015, 620 000 personnes travaillent dans les secteurs culturels (2,4 % de la population active), principalement dans le livre et la presse (18 %), les arts visuels (16 %) et l’audiovisuel (15 %). Un tiers des actifs travaillant dans les secteurs culturels sont indépendants, contre seulement 12 % dans la population active.
Les racines de la complexité en mosaïque
Authors: Chapouthier Georges
Published: February 2018

Selon le modèle de la complexité en mosaïque, inspiré par l’anatomie des êtres vivants, la complexité émerge par l’application répétée de deux grands principes : juxtaposition d’unités similaires et du même ordre de complexité, puis intégration de ces unités dans un ensemble plus complexe dont elles constituent des parties, tout en conservant une certaine autonomie, comme les tesselles d’une mosaïque. Reposant sur la non-séparation d’unités issues de la reproduction asexuée, ce modèle est compatible avec le darwinisme sans être strictement darwinien. Il a pu être généralisé à d’autres domaines : langage, création littéraire et musicale, urbanisme, robotique et même astrophysique.
L’architecture fonctionnelle du langage et le modèle de la complexité en mosaïque
Authors: Robert Stéphane
Published: February 2018

La séquentialité formelle du langage est traversée par un emboîtement de niveaux structurels qui peut être décrit suivant le modèle de la complexité en mosaïque issu de la description du vivant : les unités minimales d’un premier niveau sont regroupées par juxtaposition pour être intégrées en unités du niveau supérieur où elles se spécialisent dans de nouvelles fonctions. Ce modèle s’applique également à la construction du sens d’un énoncé où l’intégration du sens des parties dans le tout se caractérise par de remarquables effets non linéaires. Enfin, la distinction entre différents degrés d’intégration des parties dans le système permet d’ébaucher une typologie de la complexité structurelle des langues et des états de langues et d’ouvrir sur un modèle de production du langage.
La morale en mosaïque
Authors: Nurock Vanessa
Published: February 2018

En développant l’hypothèse de la mosaïque proposée par Georges Chapouthier, on peut dresser les grandes lignes d’une morale en mosaïque et dégager les conséquences normatives de cette hypothèse. L’idée d’une mosaïque morale peut s’envisager de deux manières complémentaires, d’une part en s’intéressant à la question du pluralisme moral, en y incluant notamment la morale animale et la question des relations morales, d’autre part, en interrogeant la mosaïque que constitue notre capacité morale.
De l’ontologie au droit : quels fondements ?
Authors: Barthélémy Jean-Hugues
Published: February 2018

Il s’agit d’abord de contextualiser puis de problématiser le « modèle de la complexité en mosaïque », qui fait la singularité de l’ontologie cosmogénétique de Chapouthier. Deux questions fondamentales sont alors abordées : quel rôle doit revenir à l’ontologie au sein des différentes problématiques de la philosophie ? Et que faut-il entendre par « droit » lorsqu’on se propose d’accorder des droits à l’animal ? C’est l’articulation entre ontologie, éthique et droit qui se prête à une refondation réorganisatrice. Un dialogue s’esquisse ainsi entre l’anthropologie proposée par Chapouthier et celle qui conduit à « l’humanisme décentré ».
Mosaïque et intégration : éléments historiques et épistémologiques
Authors: Dupont Jean-Claude
Published: February 2018

Le modèle de complexité en mosaïque proposé par Georges Chapouthier repose sur deux principes de base : juxtaposition et intégration, mis au service d’une conception évolutionniste générale. La recherche d’une définition de l’intégration passe par une reconstitution de la généalogie du concept depuis Herbert Spencer, jusqu’à son enracinement dans la pensée biologique. Ce faisant, nous montrons la convergence du projet de Chapouthier avec la pensée spencérienne.
La complexité en mosaïque à l’épreuve du scepticisme
Authors: Forest Denis
Published: February 2018

Trois questions sont posées au modèle de la complexité en mosaïque. La première porte sur la relation entre le modèle et son illustration, en privilégiant l’exemple du cortex cérébral et des conceptions rivales qui peuvent en être proposées. La seconde porte sur l’universalité des « principes » de juxtaposition et d’intégration, et sur la relation entre science et philosophie. La troisième porte sur la limitation du nombre de principes à deux : peut-on envisager d’autres manières de faire des touts que la juxtaposition et l’intégration ?
Réponses : approches philosophiques de la complexité en mosaïque
Authors: Chapouthier Georges
Published: February 2018

Les analyses qui précèdent permettent d’esquisser deux types d’extension de la problématique soulevée. D’une part le modèle peut être étendu au langage et à la morale et comparé aux thèses de Herbert Spencer. D’autre part se dessinent aussi des « au-delà » philosophiques du modèle, qui mènent à des horizons ontologiques ou à des questionnements profonds sur la nature métaphysique du modèle proposé.
Un professeur de philosophie débutant sous le second Empire
Authors: Trochu Thibaud
Published: February 2018

Deux lettres de 1866 et 1867 adressées par Théodule Ribot, alors jeune professeur de philosophie au lycée de Vesoul, à son condisciple Léonce Pingaud, et les rapports administratifs et pédagogiques rédigés dans les mêmes années par ses supérieurs hiérarchiques sur sa conduite et son enseignement permettent d’illustrer la situation des professeurs de philosophie sous le Second Empire.
Genomic integration of HHV-6 mimicking viral reactivation after autologous stem cell transplantation
Authors: Mineri Rossana , Mariotti Jacopo , Sarina Barbara , Morabito Lucio , Crocchiolo Roberto , Bramanti Stefania , Sarno Tiziana , Tordato Federica , Carlo-stella Carmelo , Santoro Armando , Castagna Luca
Published: February 2018

The monitoring of HHV-6 after allogeneic hematopoietic stem cell transplantation (HSTC) has proven to be useful in preventing life-threatening complications; however, the pathogenic role of HHV-6 after autologous HSCT is not well-characterized, although viral reactivation might be responsible for significant complications even after autologous HSCT. Here we report for the first time to our knowledge the case of a patient with genomic integration of HHV-6, presenting with high titers of HHV-6 after autologous HSCT, mimicking HHV-6 reactivation. The presence of viral DNA in the follicle bulb confirmed the genomic integration and allowed the discontinuation of the antiviral treatment to the patient.  This case might be helpful for discriminate HHV-6 reactivation from viral integration, thus avoiding unnecessary and potentially toxic antiviral therapy once the genomic integration is confirmed.
ELOTUZUMAB FOR THE TREATMENT OF RELAPSED OR REFRACTORY MULTIPLE MYELOMA, WITH SPECIAL REFERENCE TO ITS MODES OF ACTION AND SLAMF7 SIGNALING
Authors: Taniwaki Masafumi , Yoshida Mihoko , Matsumoto Yosuke , Shimura Kazuho , Kuroda Junya , Kaneko Hiroto
Published: February 2018

Elotuzumab, targeting signaling lymphocytic activation molecule family 7 (SLAMF7), has been approved in combination with lenalidomide and dexamethasone   (ELd)   for relapsed/refractory  multiple myeloma (MM) based on the findings of the phase III randomized trial  ELOQUENT-2 (NCT01239797). Four-year  follow-up  analyses  of  ELOQUENT-2 have demonstrated  that  progression-free survival was 21%  in  ELd  versus  14%  in  Ld. Elotuzumab binds a unique epitope on the membrane IgC2 domain of SLAMF7, exhibiting a dual mechanism of  action:  natural  killer  (NK)  cell-mediated  antibody-dependent  cellular  cytotoxicity  (ADCC) and  enhancement  of  NK  cell  activity.  The  ADCC  is  mediated  through  engagement  between  Fc portion  of  elotuzumab  and  FcgRIIIa/CD16  on  NK  cells. Enhanced NK cell cytotoxicity results fromm phosphorylation  of  the  immunoreceptor  tyrosine-based  switch  motif  (ITSM)  that  is induced via elotuzumab binding and recruits the SLAM-associated adaptor protein EAT-2.The coupling of EAT-2 to the phospholipase Cg enzymes SH2 domain leads to enhanced Ca2+. Influx and MAPK/Erk pathway activation, resulting in granule polarization and enhanced exocytosis inNK  cells. Elotuzumab  does not stimulate the  proliferation of MM cells due to a lack of EAT-2.The  inhibitory  effects  of  elotuzumab  on  MM  cell  growth  are  not  induced by  the lack  of  CD45, even  though  SHP-2,  SHP-1,  SHIP-1,  and  Csk may be  recruited  to  phosphorylated  ITSM  of SLAMF7.  ELd  improves PFS in patients  with  high-risk  cytogenetics,  i.e.  t(4;14),  del(17p),  and 1q21  gain/amplification. Since  the immune  state  is  paralytic  in  advanced  MM,  the  efficacy  of ELd with minimal toxicity may bring forward for consideration of its use in the early stages of the disease.
AN OBSERVATIONAL STUDY OF THE EFFECT OF HEMOGLOBINOPATHY, ALPHA THALASSEMIA AND HEMOGLOBIN E ON P. VIVAX PARASITEMIA
Authors: Para Suparak , Mungkalasut Puncharee , Chanda Makamas , Nuchprayoon Issarang , Krundsood Srivicha , Cheepsunthorn Chalisa Louicharoen
Published: February 2018

Background: The protective effect of α-thalassemia, a common hematological disorder in Southeast Asia, against Plasmodium falciparum malaria has been well established. However, there are much less well understood the effect of α-thalassemia against P.vivax. Here, we aimed to investigate the proportion of α-thalassemia including the effect of α-thalassemia and HbE on the parasitemia of P.vivax in Southeast Asian malaria patients in Thailand.Methods: A total of 210 malaria patients, admitted to the Hospital for Tropical Diseases, Thailand during 2011-2012, consist of 159 Myanmeses, 13 Karens, 26 Thais, 3 Mons, 3 Laotians, and 6 Cambodians were recruited. Plasmodium spp. and parasite densities were determined. Group of deletion mutation (--SEA, -α3.7, -α4.2deletion) and substitution mutation (HbCS and HbE) were genotyped using multiplex gap-PCR and PCR-RFLP, respectively.Results: In our malaria patients, 17/210 homozygous and 74/210 heterozygous -α3.7 deletion were found. Only 3/210 heterozygous -α4.2 deletion and 2/210 heterozygous--SEA deletion were detected. HbE is frequently found with 6/210 homozygote and 35/210 heterozygote. The most common thalassemia allele frequencies in Myanmar population were -α3.7 deletion (0.282), followed by HbE (0.101), HbCS (0.016), -α4.2 deletion (0.009), and --SEA deletion (0.003). Only density of P.vivax in α-thalassemia trait patients (-α3.7/-α3.7, --SEA/αα, -α3.7/-α4.2) but not in silent α-thalassemia (-α3.7/αα, -α4.2/αα, ααCS/αα) were significantly higher compared with non α-thalassemia patients (p=0.027). Density of P.falciparum significantly increased in heterozygous HbE patients (p=0.046).Conclusions: Alpha-thalassemia trait is associated with high level of P.vivax parasitemia in malaria patients in Southeast Asia.
Challenges arising from use of HVDC
Authors: Ildstad Erling
Published: February 2018

Direct Current (DC) power systems have been in use since the early 1880s. However, for more than 100 years the 3 phase AC transmission system has been the dominant transmission system for electric power. The main reason for this is the ease of changing voltage levels and grid connection using reliable AC transformers and breakers. During the last 60 years new converter technology has made HVDC the most efficient and economical long distance point to pointpower transmission transportation. 

In order to satisfy the growing demand of electric energy consumption, new high capacity multi-terminal HVDC systems need to be developed. This is considered an enabling technology for access to remote renewable energy sources such as off-shore wind farms, hydroelectric power and desert solar plants.This review shows that acceptable solutions have to be found to interrupt HVDC short circuit currents. Higher voltage means that new types of reliable HVDC insulation systems have to be developed, including test procedures and designcriteria for insulation systems based upon combinations of gas, liquid and solids.
Conduction behavior of polyaniline/elastomer composites and the influence of carbon black addition
Authors: Sonerud Björn , Furuheim Knut Magne , Josefsson Staffan , Pelto Jani , Ketonen Marjo , Härkki Outi
Published: February 2018

Three different compositions of EPDM, polyaniline (PANI) and carbon black have been studied with respect to conduction properties. It could be concluded that both carbon black and polyaniline influence the low field conductivity. In addition, the influence of different conduction mechanisms was studied. Measurements on the temperature dependence of the electrical conductivity indicated that large amount of polyaniline in EPDM rubber manifested in 1D variable range hopping (1D-VRH) behavior whereas less amount, although still well above the percolation threshold, resulted in behavior more similar to the Arrhenius law. However, further studies are necessary to draw definitive conclusions on the influence of filler content. Studying the field dependent conductivity behavior it could be concluded that there is a Ohmic region at low field and a transition towards space charge limited current (SCLC) at higher field with possible influence of other conduction mechanisms.
Short and long term behavior of functionally filled polymeric insulating materials for HVDC insulators in compact gas-insulated systems
Authors: Tenzer Michael , Secklehner Maximilian , Hinrichsen Volker
Published: February 2018

Conventional insulators optimized for high-voltage alternating current transmission tend to accumulate surface and volume charges in direct voltage applications. This is especially true for gas-insulated systems, where the surrounding gas is extremely dry, thus having very low conductivity. This may result in a strong decrease of the dielectric strength of the insulators and can lead to dielectric breakdown, especially when polarity reversals are applied. Main challenges for the development of HVDC insulators are avoiding surface and volume charge accumulations and featuring both suitable capacitive and resistive field distributions. The use of polymeric insulation materials filled with functional fillers of defined low and possibly non-linear, field dependent electric conductivity avoids these charge accumulations. Several specimens of polymeric insulation materials of different, controlled conductivities for high field stress applications were produced and experimentally investigated for this contribution. Since electric conductivity depends on parameters such as temperature, humidity or long term ageing, the longterm behavior of the specimens was investigated in 1000 h tests under temperature and electrical field stress. Furthermore, tests in a high-voltage gas insulated test setup were performed in order to determine the dielectric strength of the filled polymers under high electric stationary and transient fields as present in gas insulated systems. Results of these investigations are presented and discussed in detail in this contribution.
Comparison of simulated and measured field dependent charge injection in mineral oil under dc bias
Authors: Hjortstam Olof , Sonehag Christian , Schiessling Joachim
Published: February 2018

The present study aims at the understanding of charge injection from metal electrodes into mineral oil under DC stress. The work focuses on the field dependence of the charge injection. In a previous article the electrical field in a blank oil gap with parallel electrodes is measured with a so called Kerr electro-optic technique. The data show that the electrical field is close to symmetric for low fields (~ 0.1 kV/mm) but strongly asymmetric at higher fields (~ 1 kV/mm). In the present study an ion drift model is used to analyze the data. We show that an ion drift model including a field dependent injection term can reproduce the measured results fairly well. Furthermore, the comparison of measured and simulated results shows that the charge injection is stronger from an electrode with positive polarity compared to one of negative polarity.
Surface potential decay on silicon rubber samples at reduced gas pressure
Authors: Alam Shahid , Serdyuk Yuriy V. , Gubanski Stanislaw
Published: February 2018

Accumulation of interfacial charges is an inherent feature of HVDC insulation based on solid and gaseous media. The collected surface charges can alter the geometrical electric field leading to undesirable phenomena such as partial discharges and even unexpected flashovers. In the present paper, surface potential decay on silicone rubber samples is analyzed at reduced pressures of ambient air that allows for elimination of surface charge neutralization by gas ions. Thus, influences imposed by bulk and surface conduction in the solid material are studied by means of computer simulations and experimental measurements. The results allow for identifying levels of bulk and surface conductivities above which the corresponding charge decay mechanism becomes dominant. It is shown that with a negligible space charge effect and significant surface leakage, there exists a notable spread of charge along gas-solid interface yielding visible crossover phenomenon in charge decay characteristics. It is also demonstrated that the effect of space charge in the material bulk on surface potential decay can only be significant within layers of material finer than ca. 100 μm.
Challenges when measuring the DC electric field very close to an insulator surface
Authors: Källstrand Birgitta , Borg Daniel , Walfridsson Lars , Johansson Kenneth , Doiron Charles
Published: February 2018

A small probe that can measure DC electric fields in air has been developed. As a consequence of the probe size, it is possible to measure close to the surface of e.g. an HVDC insulator, and to resolve the field with an excellent spatial resolution. However, challenges have been identified when performing measurements close to a surface and its influence on the measurement results have been quantified. Measurement procedures have been developed to be able to correct for the possible net charging of the probe.
Effect of Film Thickness and Electrode Area on the Dielectric Breakdown Characteristics of Metallized Capacitor Films
Authors: Rytöluoto Ilkka , Lahti Kari
Published: February 2018

An alternative approach for measuring breakdown characteristics of metallized and non-metallized polymer films has been previously developed at TUT. The method enables measurement of multiple breakdowns beyond the weakest point of each sample film by utilizing low-energy self-healing breakdown of metallized film. The method yields a large amount of breakdown data even from a relatively small sample area which enables the formation of detailed material-specific breakdown fingerprints. In this paper, some preliminary results of an ongoing further research on the area and thickness dependence of the breakdown characteristics of various polymer films are presented.
Developement of insulation system for variable speed driven motors; performance of a corona resistant magnet wire
Authors: Nuorala Tomi , Lehtonen Janne , Takala Markus
Published: February 2018

The amount of variable speed drive (VSD) motors and generators is growing constantly, but VSD use causes partial discharges (PDs) which are the most common reason for the winding damage. Magnet wire manufacturers have developed products that are more resistant against PDs. The objectives of this study were to resolve if the other properties of a corona resistant (CR) magnet wire are sufficient compared to reference wire. Dimension measurement, mandrel, peel, breakdown voltage and pin hole tests were made to both wires.
Enhancement of Water Tree initiation due to residual and applied Mechanical Strain on XLPE Cables
Authors: Ildstad Erling , Årdal Aarseth Simon , Faremo Hallvard
Published: February 2018

This paper present results from laboratory water tree experiments performed on samples of commercial available 6/10 kV XLPE insulated cables. The main purpose of the investigation was to examine possible water tree enhancement, due to mechanical tension of the insulationDuring water tree ageing at 50 Hz AC voltage of 14 kV (E_max = 5.2 kV/mm) the cable samples were mechanically stretched at 1%, using both static and dynamic mechanical load varying at 0.1 Hz. In addition, thermal treatment indicated a total residual longitudinal mechanical strains of 6%, frozen in during th emanufacturing process.Both the density and growth rate of vented and bow-tie water trees was found to increase with increasing applied mechanical tension. During non-strained thermal treatment the axial length of cables was reduced by about 6%. The low density of vented trees originating from te outer insulation screen supports the assumption that frozen in compressive stresses at the outer insulation surface may balance the effect of applied strain.
Influence of DC Stress Superimposed with High Frequency AC on Water Tree Growth in XLPE Insulation
Authors: Mauseth Frank , Hvidsten Sverre , Sæternes Hans-Helmer , Aakervik Jørund
Published: February 2018

Power electronics used for HVDC converters will stress cable insulation with a DC voltage with superimposed transients. The effect these transients have on the performance of the polymeric cable insulation is yet not clear. The main purpose of this work has been to investigate the effect of such transients on XLPE cable insulation when exposed to moisture. Laboratory experiments were performed on Rogowski shaped test objects with an insulation thickness of 1.3 mm. At one of the semi-conductors, 20 sodium chloride (NaCl) particles were placed in order to facilitate initiation of vented water trees. The test objects were conditioned with water at 20 °C for two months ensuring saturation of water inside the insulation system before testing.The test objects were aged with an AC voltage simulating the transients from a HVDC converter. Experiments were performed using the AC voltage with and without DC stress to investigate the influence of the DC level on the water tree growth. The ageing was done at 30 °C.Test objects were taken out and inspected for water tree growth regularly. The results show a rapid ageing caused by water treeing when exposed to the DC voltage overlaid AC voltage with a frequency of 5 kHz and a pure AC voltage stress.
Correction of Geometric Influence in Permittivity Determination
Authors: Xu Xiangdong , Bengtsson Tord , Blennow Jörgen , Gubanski Stanislaw
Published: February 2018

Determination of relative permittivity of dielectric materials is generally done with a rather low accuracy, in the order of several percent. This is in a sharp contrast to the accuracy of measurements of the dissipation factor, both usually being determined in the same measurement. A common understanding for the inferior accuracy in permittivity measurements is the effects of electrode edges. However, further studies indicate that geometric effects, arising from electrode shielding box, guard ring, electrode supporting materials, etc., also influence the accuracy significantly if the responding voltage present at the measuring electrode is non-negligible. With help of the Finite Element Method (FEM), geometric correction factors are estimated from an electrode model to increase the accuracy. This study is specially focused on the application of contact-free electrode arrangement using the air reference method. In this paper, a few examples of how geometric influences affect results are presented as well as a comparison of experimental results. From these insights, we discuss how to minimize and compensate the geometric effects.
System for detection and analysis of partial discharges under transient voltage application
Authors: Kjær Søren Valdemar , Holboell Joachim
Published: February 2018

A measuring system for detection and analysis of partial discharges (PD) in electrical insulation under fast repetitive pulse voltage application has been developed. Partial discharges can be triggered by transient voltages and are considered as being one initial cause of insulation failure.The experimental setup consists of a specially designed pulse generator for generation of fast voltage transients. The pulses are unipolar, with the peak variable voltage of up to 10 kV and with an adjustable frequency from 0 Hz to 1.7 kHz, burst frequency of up to 2 MHz.Partial discharge inception under pulse voltage application was determined by data acquisition by means of a standard oscilloscope and suitable data analyses in Matlab, using wavelet transform and denoising techniques. The measurement results are presented in a partial discharge classification pattern designed to be used in connection with fast repetitive pulses as originating from power electronics.The feasibility of the test system for insulation diagnostics was illustrated by application to twisted pairs of enamelled winding wire.The test system is suitable for achieving new results to get better knowledge of degradation mechanisms in insulating materials exposed to fast transients from eg. power electronics.
VLF Testing of High Voltage Cables, State of the Art
Authors: Mohaupt P , Miseli K , Geyer H
Published: February 2018

A new testing method for testing long and extra-long high voltage cables, called Differential Resonance Technology (DRT) is presented. The working principle, the application, as well as the several challenges for onsite testing in an on- and offshore environment are described.