bluuebunny/crossref_metadata_2025 huggingface dataset:
Respon Hasil Sawi (Brassica juncea L.) Akibat Pemberian Dosis POC Substitusi AB Mix serta Media Tanam Pada Sistem Hidroponik
Authors: E.D. Purbajanti dan Sumarsono Ghaisani Nabilah Putri,
Published: October 2021

ABSTRAKPenelitian bertujuan untuk mengkaji pengaruh dosis pupuk organik cair daun gamal substitusi nutrisi AB Mix serta jenis media tanam yang tepat untuk pertumbuhan dan produksi sawi. Penelitian dilakukan pada tanggal 18 Februari - 25 April 2018 di Laboratorium Ekologi dan Produksi Tanaman serta Green House Fakultas Peternakan dan Pertanian, Universitas Diponegoro. Penelitian menggunakan percobaan faktorial dengan Rancangan Acak Lengkap terdiri dari 3 ulangan.  Faktor pertama adalah substitusi dosis pupuk, yaitu 100% AB Mix (A1), 75% AB Mix + 25% POC (A2), 50% AB Mix + 50% POC (A3), 25% AB Mix + 75% POC (A4) dan 100% POC (A5). Faktor kedua adalah jenis media tanam, yaitu rockwool (B1) dan cocopeat (B2). Parameter yang diamati adalah tinggi tanaman, jumlah daun, berat segar, berat kering dan serapan nitrogen. Data diolah dengan analisis ragam (uji F), dan dilanjutkan dengan uji DMRT. Hasil penelitian menunjukkan perlakuan sampai dosis 50% POC + 50% AB Mix pada media tanam rockwool menghasilkan berat segar setara dengan perlakuan 100% AB Mix dengan media tanam rockwool. Kata Kunci: Sawi, nutrisi AB Mix, POC, rockwool, cocopeat.
Analisis Pendapatan Usahatani Tebu Rakyat Di Kecamatan Trangkil Kabupaten Pati (Analysis of Sugar Cane is Farmer’s Farm Income in Trangkil District Pati Regency)
Authors: T. Ekowati dan  D. Sumarjono I.B. Satriyo,
Published: October 2021

ABSTRAKPenelitian bertujuan untuk menganalisis pendapatan bersih usahatani tebu rakyat di Kecamatan Trangkil Kabupaten Pati, menganalisis pendapatan tenaga kerja usahatani tebu rakyat di Kecamatan Trangkil Kabupaten Pati dan menganalisis pendapatan mencapai Upah Minimum Kabupaten (UMK) atau tidak. Lokasi penelitian ditentukan karena Kecamatan Trangkil memiliki produksi tebu rakyat terbanyak di Kabupaten Pati. Metode yang digunakan dalam penelitian adalah survai. Penentuan lokasi penelitian secara purposive. Data yang dikumpulkan dalam penelitian ini terdiri dari data primer dan sekunder. Pemilihan sampel ditentukan dengan metode random sampling adalah 40 responden petani. Hasil penelitian menunjukan bahwa produksi rata-rata tebu petani di Kecamatan Trangkil sebesar 136,3275 kg/musim tanam, dengan jumlah produksi tebu adalah 8179,65 kg/musim tanam, sehingga didapatkan penerimaan sebanyak Rp 69.527.025. Pendapatan bersih petani tebu di Kecamatan Trangkil dalam satu kali musim panen adalah Rp 46.801.988 atau dalam pendapatan bersih perbulan adalah Rp 4.680.198. Upah Minimum Kabupaten (UMK) Kabupaten Pati tahun 2018 adalah  sebesar Rp 1.585.000/bulan sedangkan rata-rata pendapatan yang diperoleh petani tebu di Kecamatan Trangkil Kabupaten Pati sebesar Rp 46.801.988/musim tanam. Rata-rata pendapatan petani tebu dalam satu bulan yaitu Rp 4.680.198. Kata Kunci: Pendapatan, Produksi, Tebu Rakyat, Upah Minimum Kabupaten (UMK), Usahatani
Pengaruh Perbedaan Panjang Kandang Dan Zona Penempatan Di Dalam Kandang Closed House Terhadap Total Leukosit Dan Differensial Leukosit Ayam Broiler
Authors: Teysar Adi Sarjana  dan  Retno Murwani Siti Sulaibah,
Published: October 2021

ABSTRAK            Penelitian bertujuan untuk mengkaji pengaruh perbedaan panjang kandang dan zona penempatan di dalam kandang closed house terhadap total leukosit dan differensial leukosit ayam broiler. Materi penelitian adalah 2 unit kandang closed house ukuran panjang 60 meter kapasitas 11.000 ekor dan ukuran panjang 120 meter kapasitas 22.000 ekor, pada penelitian digunakan 600 ekor ayam broiler dengan Rancangan Acak Kelompok Pola Split Plot dan dua faktor. Faktor pertama panjang kandang ukuran 60 dan 120 meter dan faktor kedua penempatan zona di dalam kandang yang dibagi menjadi 4 zona yaitu zona 1 diukur 0 meter jarak dari inlet, zona 2 diukur pada 1/4 panjang kandang, zona 3 diukur pada 1/2 panjang kandang, zona 4 diukur pada 3/4 panjang kandang. Hasil penelitian menunjukan ada interaksi pengaruh perbedaan panjang kandang dan penempatan zona di dalam kandang terhadap jumlah eusinofil. Panjang kandang 60 meter dan zona terdekat dengan inlet mempunyai jumlah eosinofil tertinggi. Panjang kandang 120 meter signifikan menurunkan jumlah heterofil. Zona yang semakin jauh dari inlet signifikan menurunkan total leukosit. Dapat disimpulkan bahwa broiler yang ditempatkan pada panjang kandang 60 meter dengan zona semakin dekat dengan inlet mempunyai jumlah eosinofil tertinggi. Kandang yang lebih panjang dapat menurunkan jumlah heterofil dan zona yang semakin jauh dari inlet dapat menurunkan total leukosit ayam broiler. Kata Kunci : closed house, panjang kandang, zona di dalam kandang, total leukosit, differensial leukosit, broiler
Pengaruh Biaya Sarana Produksi Dan Tenaga Kerja Terhadap Pendapatan Usahatani Cabai Rawit Merah Di Desa Kesambi Kecamatan Mejobo Kabupaten Kudus
Authors: Saparto  dan  Wiharso M. Faela Sofa,
Published: October 2021

ABSTRAK            Penelitian bertujuan untuk mengetahui: (1) pendapatan usahatani cabai rawit merah; (2) pengaruh biaya sarana produksi dan tenaga kerja terhadap pendapatan cabai rawit merah.  Penelitian dilakukan di Desa Kesambi Kecamatan Mejobo Kabupaten Kudus pada bulan September 2018 s.d Juli 2019.  Jumlah populasi petani sebanyak 130 orang dengan luas kepemilikan lahan berkisar 0,100 s.d. 0,500 ha. Penelitian dengan metode survei dan penentuan responden menggunakan metode sampling Stratified Random Sampling dengan jumlah sampel 25% atau 33 responden.  Pengumpulan data dengan wawancara dan pengamatan.  Data yang dicatat adalah data biaya pengeluaran berupa biaya : bibit, pupuk, pestisida, tenaga kerja, penyusutan peralatan, sewa lahan, sewa mesin, dan pajak. Data penerimaan diperoleh dari data produksi dikalikan harga jual. Pendapatan petani dianalisis dengan analisis biaya dan penerimaan. Pengaruh biaya sarana produksi dan tenaga kerja terhadap pendapatan dianalisis dengan analisis regresi linier berganda.  Hasil penelitian : (1) Rata-rata pendapatan per hektar sebesar Rp. 42.499.673,-; (2) Ada pengaruh yang sangat nyata (P1%) biaya sarana produksi dan tenaga kerja terhadap pendapatan.  Persamaan regresi penduganya : Y = 94.879 + 54,078 X1** – 8,021 X2** + 7,207 X3** + 2,104 X4* ; (X1=bibit, X2=pupuk, X3=pestisida, X4=tenaga kerja); R2ajd = 0,999.  Kesimpulan : usahatani cabai rawit merah menguntungkan dan ada pengaruh yang sangat nyata dari biaya sarana produksi dan tenaga kerja terhadap pendapatan usahatani cabai rawit merah di Desa Kesambi Kecamatan Mejobo Kabupaten Kudus. Kata kunci : pendapatan, biaya sarana produksi tenaga, cabai rawit
Unconstitutional legislative solutions enshrined by the 1968 Code of Criminal Procedure
Authors: TOADER TUDOREL , SAFTA MARIETA
Published: October 2021

This study presents development of the case-law of the Constitutional Court, from
declaring the unconstitutionality of the legal norm to declaring the
unconstitutionality of the legislative solution promoted by the respective norm,
with special reference to criminal procedure law. The constitutional review
transcends the strict framework of the limits of the referrals addressed to the
Court, for the purpose to drain the legislative system of those provisions that
resume legislative solutions found to be unconstitutional. Thus emphasizes the
sanctioning effect on the legal rule that constituted the subject matter of the
constitutional review, as well as a preventive effect, given the legislator’s
inability to resume a legislative solution declared unconstitutional, except for
the situation where a change in the socio-economic context would occur.
Constitutional reform in Ukraine - a means of improving the judiciary
Authors: ȘCERBANIUK OLEKSANDR
Published: October 2021

This study reveals recent constitutional developments in Ukraine, notably in the
constitutional jurisdiction, emphasizing the strengthening of the Constitutional
Court’s role, as a key institution that aims at protecting and developing the
principles and values of constitutionalism and, thereby, the rule of law.
Judges and assistant -magistrates within constitutional courts
Authors: TOADER TUDOREL , SAFTA MARIETA
Published: October 2021

This study brings together the decision component into the constitutional jurisdiction
(constitutional judge) and the one supporting the decision-making
process (assistant-magistrate/referendary/legal assistant/adviser etc. of the
constitutional judge). The analysis regarding the appointment/entry
requirements into the profession, the duties and the status of the constitutional
judge and respectively of the assistant-magistrate, aims at emphasizing, in
particular, the complementary roles of the two analysed offices and their
importance for the exercise of the constitutional justice.
Roughness into the Channel Create the Flood Situation - A Case Study at Lower Reach of Shilabati River Basin, Paschim Medinipur, West Bengal
Authors: Chaudhury Dr. Suparna
Published: October 2021

Roughness into the channel of streams and rivers determines several important hydraulic parameters must be properly represented in models for estimating water discharge and sediment transport. Hydraulic parameters mainly gradient, hydraulic radius, width, width-depth ratio, wetted perimeter and cross sectional area are considered for analysing the ability of channels to carry discharge but resisting forces are opposing component of this movement. This paper reviews to evaluate the different approaches used to identify the roughness and to understanding of how flow resistance is created by roughness in open channel flows. The Shilabati river basin embraces a portion of the eastern fringe of the Chotonagpur plateau. South west monsoon is the principal source of rainfall in this area. After the heavy storm, the low lying depression in the lower reach of this catchment attracts huge flood water and sediments from it upper catchment, sub-tributaries and larger catchments of neighbouring rivers mainly Damodar, Darakeswar, and Kangsabati. The upper courses are steeper (0.84) and rocky facilitating easy drainage, that gradually concentrates at lower reach as it lost its capacity due to sudden reduction of gradient (Gadghat, 0.08; Bandar, 0.02). In the Shilabati river the cross sectional area changes through time in response to fluctuations in discharge. Channel slopes near these gauging stations are surveyed, that shows continuously decreasing tendency towards lower catchment. Capacity of channel is measured by conveyance of flow. Roughness coefficient value at three gauging station (Banka 0.50, Gadghat near Ghatal 0.82 and at estuary, Banka,1) measuring by the Manning’s equation depicts that the resistance to flow increases steadily at downstream. Channel substrate mainly vegetation and netting also influences the boundary roughness and flow resistance. Friction from sediment load mainly grain roughness are responsible for generating resistance which steadily declines movement and create jamming of water which ultimately leads to flood and water storage situation.
Picudo del nopal (Metamasius spinolae Gyllenhal): florívoro y frugívoro de Opuntiacanta brigiensis Lynch (Cactaceae)
Authors: Cárdenas-Ramos Diana , Mandujano María C.
Published: October 2021

Metamasius spinolae es un insecto fitófago que ataca las estructuras vegetativas de algunos géneros de la familia Cactaceae. El objetivo del trabajo es dar a conocer los hábitos florívoros y frugívoros de M. spinolae. Entre 2017 y 2018, observaciones mensuales se realizaron para registrar la incidencia de ataque de este coleóptero y describir el daño en las estructuras vegetativas y reproductivas de Opuntia cantabrigiensis. Metamasius spinolae tiene hábitos herbívoros al consumir cladodios jóvenes y areolas. Este insecto es un florívoro que consume parcialmente el perianto y elimina el gineceo de los botones. El daño impide la reproducción exitosa de los individuos. Este insecto actúa como frugívoro al alimentarse de la pulpa de los frutos maduros. Lo importante es apreciar la conducta depredadora de M. spinolae debido a que su hábito alimenticio no solo se restringe a las estructuras vegetativas de los hospederos que ataca.
MEMBANGUN MOTIVASI BELAJAR MELALUI PEMBELAJARAN AKTIF DAN PENGGUNAAN KOMIK BERBASIS DISCOVERY LEARNING
Authors: SYAHREZA ACHMAD
Published: October 2021

Belajar di masa pandemi covid-19 memberi dampak bagi peserta didik, diantaranya ialah penurunan motivasi belajar. Kondisi ini merupakan tantangan bagi guru, dan hal ini membuka pintu untuk menemukan solusi atas persoalan yang muncul. Salah satu upaya yang dilakukan ialah pembelajaran aktif dan penggunaan komik berbasis discovery learning. Metode penelitian ini disusun dan dilakukan dengan pendekatan kualitatif deskriptif melalui studi kasus. Data yang diperoleh dari studi literatur sebagai data sekunder, adapun data primer diperoleh dari wawancara, angket, observasi, dan dokumentasi. Dalam penerapannya diperoleh hasil yang sesuai dengan apa yang diharapkan, berdasarkan hasil wawancara dan angket bahwa pembelajaran aktif dan penggunaan komik mendorong motivasi belajar peserta didik. Oleh karena itu, pembelajaran aktif dan penggunaan komik yang diteliti dengan pendekatan kualitatif deskriptif dalam studi kasus mampu membangun motivasi belajar siswa pada masa pandemi covid-19 di SMP Islam Integral Luqman Al Hakim, Kota Batam.
PENGARUH KEPEMIMPINAN KEPALA SEKOLAH DALAM ORGANISASI TERHADAP KINERJA GURU
Authors: DARMININGSIH DARMININGSIH
Published: October 2021

Penelitian ini bertujuan untuk mengetahui pengaruh kepemimpinan kepala sekolah, dalam organisasi dan kinerja guru di Gugus I Kecamatan Seberida. Untuk menganalisis pengaruh kepemimpinan kepala sekolah dalam organisasi secara parsial terhadap kinerja guru di Gugus I Kecamatan Seberinda. Penelitian ini berjenis eksplanatory. Populasi dalam penelitian ini adalah semua guru di Gugus I Kecamatan Seberida yang berjumlah 40 orang. Metode sensus sampling digunakan mengingat jumlah populasinya sedikit. Dengan demikian jumlah sampel penelitian ini sebanyak 40 orang. Teknik analisis data pada penelitian ini adalah menggunakan statistic inferensial dengan menggunakan analisis regresi linier berganda. Hasil analisis data menunjukkan bahwa kondisi variabel kepemimpinan kepala sekolah, Iklim organisasi dan kinerja guru di SD Negeri Gugus 1 Kecamatan Seberida dalam kondisi baik. Secara simultan variabel kepemimpinan kepala sekolah dalam organisasi mempunyai pengaruh yang signifikan terhadap kinerja guru di SD Negeri Gugus 1 Kecamatan Seberida. Secara parsial variabel kepemimpinan kepala sekolah dalam organisasi mempunyai pengaruh yang signifikan terhadap kinerja guru di SD Negeri Gugus 1 Kecamatan Seberida.
HUBUNGAN METODE DISKUSI KELOMPOK DENGAN MOTIVASI BELAJAR TERHADAP DAYA SERAP PESERTA DIDIK PADA PEMBELAJARAN PAK DAN BUDI PEKERTI
Authors: SOPAKUA SAMEL , LABOBAR WILHELMUS , LATUIHAMALLO FEBY
Published: October 2021

Penerapan metode diskusi secara tepat dapat mendorong terjadinya interaksi peserta didik selama pembelajaran yang akan berdampak pada daya serap peserta didik. Interaksi di kelas melalui metode diskusi dapat menumbuhkan motivasi belajar peserta didik. Dengan motivasi yang terus tumbuh membuat peserta didik dapat menyerap dengan baik materi pembelajaran. Penelitian ini merupakan kuantitatif dengan uji statistik korelasi. Hasil penelitian menunjukan bahwa (1) Terdapat hubungan yang positif dan signifikan antara metode diskusi kelompok dengan daya serap peserta didik pada Mata pelajaran PAK di SMP. Dengan koefisien korelasi sebesar 0,418 dan nilai kontribusi variabel X1 terhadap Y sebesar 17,74 % dikategorikan sedang. (2) Terdapat hubungan yang positif dan signifikan antara motivasi belajar siswa dengan daya serap siswa. Dengan koefisien korelasi sebesar 0,418 dan nilai kontribusi variabel X2 terhadap Y sebesar 18,58% dikategorikan sedang. (2) Terdapat hubungan yang positif dan signifikan antara metode diskusi kelompok dan motivasi belajar dengan daya serap peserta didik. Dengan koefisien korelasi ganda sebesar 0,498, dikategorikan sedang dengan nilai kontribusi variabel X1, X2 terhadap Y sebesar 24,80%. Hubungan ini menunjukan Fhitung = 91,223 > Ftabel = 4,78 sehingga dapat disimpulkan bahwa makin tinggi dan baik penerapan metode diskusi dan motivasi belajar maka semakin tinggi daya serap peserta didik pada Mata pelajaran PAK di SMP. Demikian pula sebaliknya, makin rendah metode diskusi kelompok dan motivasi belajar maka semakin rendah daya serap siswa pada di Mata pelajaran PAK di SMP.
PENGARUH GAME HIDE A WORD TERHADAP KEMAMPUAN BERBICARA BAHASA INGGRIS SISWA
Authors: HARTIWI JUNI
Published: October 2021

Dalam pembelajaran yang dilakukan oleh guru untuk membantu siswa agar lebih terampil menggunakan bahasa yang sedang dipelajari, sering kali game menjadi salah satu pilihannya. Ada ratusan game yang bisa digunakan dalam proses belajar mengajar. Secara alamiah, kebanyakan siswa menyukai game dalam dunia mereka, salah satunya adalah Game Hide a Word. Penelitian ini bertujuan untuk mencari tahu apakah Game Hide a Word dapat meningkatkan kemampuan berbicara bahasa Inggris mahasiswa. Subjek penelitian ini adalah mahasiswa D3MI2 AMIK Dian Cipta Cendikia yang berjumlah 38 orang. Hasil penelitian menunjukkan bahwa Game Hide a Word berpengaruh yang positif dan signifikan terhadap kemampuan berbicara mahasiswa, terutama pada komponen accuracy dan fluency. Yang  mencakup ketepatan kalimat yang dibuat oleh mahasiswa dan kelancaran mahasiswa dalam menyampaikan kalimat secara lisan.
Radiative and microphysical responses of clouds to an anomalous increase in fire particles over the Maritime Continent in 2015
Authors: Takeishi Azusa , Wang Chien
Published: October 2021

Abstract. The year of 2015 was an extremely dry year for Southeast Asia where the direct impact of strong El Niño was in play. As a result of this dryness and the relative lack of rainfall, an extraordinary amount of aerosol particles from biomass burning remained in the atmosphere over the Maritime Continent during the fire season. This study uses the Weather Research and Forecasting model coupled with Chemistry to understand the impacts of these fire particles on cloud microphysics and radiation during the peak biomass burning season in September. Our simulations, one with fire particles and the other without them, cover the entire Maritime Continent region at a cloud-resolving resolution (4 km) for the entire month of September in 2015. The comparison of the simulations shows a clear sign of precipitation enhancement by fire particles through microphysical effects; smaller cloud droplets remain longer in the atmosphere to later form ice crystals, and/or they are more easily collected by ice-phase hydrometeors, in comparison to droplets under no fire influences. As a result, mass of ice-phase hydrometeors increases in the simulation with fire particles, so does rainfall. On the other hand, we see no clear sign of temperature differences between the two simulations that could stem from the semi-direct effects of aerosols by absorbing the incoming solar radiation. Clouds are more reflective in the simulation with fire particles as ice mass increases. Combined with the direct scattering of sunlight by aerosols, the simulation with fire particles shows higher albedo over the simulation domain on average. The simulated response of clouds to fire particles in our simulations clearly differs from what was presented by two previous studies that modeled aerosol-cloud interaction in years with different phases of El Niño-Southern Oscillation (ENSO), suggesting a further need for an investigation on the possible modulation of fire-aerosol-convection interaction by ENSO.
SURVEY ON THE USE OF CARBAPENEM ANTIBIOTICS AT CAN THO CHILDREN’S HOSPITAL
Authors: Huong Bui Dang Lan , Tri Bui Dang Minh , Ngan Le Thi Kim
Published: October 2021

Objective: To survey the use of carbapenem antibiotics at Can Tho Children’s Hospital. Objects and methods: Retrospective-descriptive study on 140 medical records of patients being treated at departments of Can Tho Children’s Hospital during the period from June 1st, 2020 to December 31st, 2020. Results: 26.43% of carbapenems were indicated empirically initiate, 73.57% of carbapenem was indicated in alternative regimens as the presence of microbiological results or worsened or impaired patient status. Carbapenem was mainly used in combination regimens. The proportion of the combination in the initiation regimen was 100%. In which, the proportion of combination regimen between carbapenem and an antibiotic (or vancomycin or gentamicin) was mainly. The rate of combination of three antibiotics was 18.9%. In the replacement regimen, the proportion of combination regimen was 79.6%. Of these, 57.3% of the carbapenem was combined with another antibiotic, most of which was combined with vancomycin. Combination regimen of three or four antibiotics accounted for a low percentage. Conclusion: 26.43% of carbapenem was indicated empirically initiate, 73.57% of carbapenem was indicated in an alternative regimen in the presence of microbiological results or worsened or impaired patient status. Carbapenem was mainly used in combination regimens.
THE DIAGNOSTIC VALUE OF MAGNETIC RESONANCE IMAGING IN SUBACROMIAL IMPINGEMENT SYNDROME
Authors: Nguyet Dang Bich , Long Nguyen Tien , Lenh Bui Van , Trung Nguyen Quang
Published: October 2021

The retrospective study was performed on 45 patients with subacromial impingement syndrome who underwent magnetic resonance imaging (MRI) which then were compared with the results of their arthroscopy.

Results: 95.2% out of the cases were found to have type II and III acromion morphology; 73.8% had subacromial enthesophyte spurs; 66.7% had subacromial bursitis; 97.6% showed lesions of supraspinatus tendons in which partial–thickness rotator cuff tear was the most commonly seen. MRI showed a sensitivity (Sn) of 91.6%, specificity (Sp) of 72.2%, positive predictive value (PPV) of 81.4%, negative predictive value (NPV) of 86.67% in diagnosing subacromial bursitis. For partial-thickness rotator cuff tear, it showed a Sn of 92.5%, Sp of 93.3%, PPV of 96.1%, NPV of 87.5%. In evaluation of full-thickness rotator cuff tear, MRI showed a Sn of 100% and Sp of 100%.
THE SITUATION OF PRATICE CERVICAL CANCER PREVENTION AMONG REPRODUCTIVE AGE WOMEN AND HAVING GYNECOLOGICAL EXAMINATION AT LAM DONG GENERAL HOSPITAL
Authors: Hanh Nguyen Thi Hong
Published: October 2021

Objectives: The aims of this study to assess the practice of preventing cervical cancer of 15 - 49 years old and having gynecological examination women at Lam Dong General Hospital. Research method: A cross-sectional description. Interviewed practice about cervical cancer prevention of 400 women. Results: Over the course of the study, 400 women showed the number of women who had not been vaccinated is still high at 85.5%, the rate who had not been screened for cervical cancer is 62.3%. Based on the results of the study, we recommend that reproductive age women should be communicated more frequently about HPV vaccination and periodic cervical cancer screening to prevent cervical cancer.
ASSESSMENT OF THE SITUATION OF USE OF BLOOD PRESSURED DRUGS IN THE TREATMENT OF HIGH BLOOD PRESSURE FOR OUTCOME PATIENTS AT NAM DINH PROVINCIAL HOSPITAL IN JANUARY 2021
Authors: Khanh Nguyen Thi , Duong Nguyen Thi Tuyet
Published: October 2021

Hypertension is a disease that seriously affects the health and life expectancy of the community, playing a major etiological role in target organ damage. The selection of antihypertensive drugs to ensure reasonable safety and effectiveness is always a matter of concern of the medical industry. Applying the cross-sectional method on 2,640 patients being examined and treated for hypertension at Nam Dinh general hospital, it was found that 54.67% female patients accounted for the majority. The age of disease in both sexes is over 50 years old with a relatively high frequency of comorbidities. Most of them were prescribed drug combinations in treatment 77,9%. The group of ACE inhibitors + calcium blockers is the most common combination. ACE inhibitors are also the most commonly prescribed drugs in monotherapy. 11,4% of cases had adverse drug interactions, the most dangerous combination is UCMC + Potassium chloride and UCMC + Spironolactone causing hypokalemia. The most common interaction between beta-blockers and calcium blockers increases the antihypertensive effect.
KNOWLEDGE, PRACTICE TOWARD COVID-19 PREVENTION AMONG PEOPLE LIVING IN TAN PHU DISTRICT, HO CHI MINH CITY 2020
Authors: Ha Do Thi , Thuy Le Thuy Bich , Tinh Le Van
Published: October 2021

This study aims to assess the accessibility of information ressources and knowledge, practice toward COVID-19 prevention among people living in Tan Phu district, at Ho Chi Minh City. Cross-sectional study was performed from June 2020 and used two-stage random sampling. Data was collected by self-management questionnaire. Television and the Internet are most commonly accessed. Many people underrate COVID-19 infected risk in healthy people, children, and young people, and misperception that only wearing masks properly does not need to use other precautions, limiting hand washing practices and cleaning surfaces. Health education and communication programs need to pay more attention to the limitations of knowledge and practice, and choose appropriate communication channels to improve the effectiveness of COVID-19 prevention and control
Effectiveness of Comprehensive Educational Package on Knowledge Regarding Promotion of Health and Prevention of Complication among Hypertensive Patients at Selected Hospital, Tamilnadu
Authors: J Hema. , R Karthi.
Published: October 2021

Aim: to assess the effectiveness of a comprehensive educational package on knowledge regarding promotion of health and prevention of complications among hypertensive patients.
Objectives: (i) To assess the pre and post test level of knowledge regarding promotion of health and prevention of complications among hypertensive patients. (ii) To evaluate the effectiveness of a comprehensive educational package on knowledge regarding promotion of health and prevention of complications among hypertensive patients. (iii) To find out the association between the post test level of knowledge on the promotion of health and prevention of complications with selected socio-demographic variables of patients with hypertension.
Methodology: A Pre experimental research design was carried out in this study. 60 samples were selected by using non-probability purposive sampling technique. The pre and post test level of knowledge was assessed by using structured knowledge questionnaires.
Results: The pre test mean was 11.5 with a standard deviation of 3.24 and the post test mean was 24.37 with a standard deviation of 2.98. The mean difference of pre and post test is 12.87; standard error is 0.29. The ‘T’ value is 44.37 is Highly Significant at p<0.05 it indicates that the knowledge level of hypertensive patients regarding promotion of health and prevention of complications was increased after the comprehensive educational package.
Conclusion: The study concluded that the level of knowledge among hypertensive patients is increased after giving a comprehensive educational package and it proved that a comprehensive educational package increases the level of knowledge.

Keywords: Comprehensive educational package.
Effectiveness of Structured Teaching Programme on Knowledge Regarding Oral Health Hazards among Tobacco Users in Selected Village at Villupuram
Authors: Porselvi M. , R Karthi. , Kumar G.Ranjith
Published: October 2021

Aim: The study aims to create awareness among Tobacco users on knowledge regarding Oral Health Hazards.
Objectives:
i) To assess the pre and post test level of knowledge of oral health hazards among tobacco users.
ii) To assess the effectiveness of structured teaching programme on knowledge of oral health hazards among tobacco users.
iii) To find the association between post test level of knowledge regarding oral health hazards among tobacco users with their socio demographic variables.
Methods & Materials: A quantitative research approach-Pre-experimental research design with one group pre test and post test design was adopted. 50 samples were selected for the study by using non probability purposive sampling technique.
Results: The study findings shows that in pre test level of knowledge among 50 samples 42(84%) had inadequate knowledge and 8(16%) had moderate adequate knowledge. In post test level of knowledge among 50 samples 33(66%) had moderate adequate knowledge and 17(34%) had had excellent knowledge. The pre test mean was 5.74 with the standard deviation of 10.29 and the post test mean was 14.6 with the standard deviation of 9.91 the mean difference of pre and post is 8.86; standard error is 1.401 ‘t’ value is 34.775 significant at p<0.05 it indicates that the knowledge level of tobacco users improved after structured teaching programme. The finding of the study shows that there is significant association between level of knowledge with occupation p<0.05.
Conclusion: The study finding shows that, the post test level of knowledge is better than the pre-test knowledge. Hence it can be concluded that, structured teaching programme on oral health hazards was effective in improving the knowledge level among tobacco users.

Keywords: Tobacco users, Oral Health Hazards.
Introspecting the Role of Gram Panchayat in Structuring Rural Economy: An Experience from Bhograi Block in Odisha during COVID-19
Authors: Jena Dr. Dhirendra Kumar
Published: October 2021

PRIs were established with a hope to strengthen the rural India. But during Covid-19, it was experienced that they were not even able to support for livelihood to the rural people. Even in the midst of pandemic, though there was life threat situation, people migrated to cities in search of their livelihood. In this backdrop, this paper highlights the available livelihood supportive infrastructure, livelihood generating base and livelihood supporting mechanisms and schemes and unutilized natural resources in the Gram Panchayats. Particularly, this paper focuses on the strength of Gram Panchayat’s self fund, schemes and activities excluding central and state government funding and schemes. The work is produced by the data from both primary and secondary sources. And to make it more scientific, both quantitative and qualitative methods are applied. For this work, Bhograi block of the district of Balasore in Odisha has been taken as area of study. From the study, it is experienced that there is available resources lying unutilised but due to lack of interest, attitude, commitment of the local representatives and officials of Gram Panchayat resources can’t be utilized to harness benefits for people creating jobs and engagements. Finally, some remedial measures like behavioural and attitudinal autonomy of the officials, political neutrality, constitution of Panchayat Development Council (PDC) etc. are suggested to over the problem.

Keywords: Gram Panchayat, Rural Economy, Bhograi Block, Odisha, COVID-19
Le management de continuité d’activité en période de crise sanitaire : cas des entreprises de FES Shore
Authors: HABBANI Souad , EL JAMOUSSI Yasmina
Published: October 2021

Le Maroc, à l’instar du monde souffre de la propagation du coronavirus, cette pandémie qui a mis en danger non seulement l’existence de l’être humain, mais a impacté également l’économie nationale et internationale, cette dernière a été estimé en tant que pire des crises qu’à connu le monde depuis la guerre mondiale, ce qui amène a posé la question sur la place des entreprises en tant que premières entités impactées par cette crise et leurs comportement afin d’assurer la continuité d’activité et de minimiser le maximum possible les conséquences négative sur la rentabilité.

Le management de continuité d’activité intervient donc pour aider les entreprises à faire face à des situations imprévues comme le cas du covid 19, pouvant affecter son fonctionnement normal.
Une expansion de l’économie vers l’environnement
Authors: LEHMER Oumaima , El ABBADI Abderrazak
Published: October 2021

Les patrimoines naturel et culturel sont minés par les actions humaines sournoises, le rapport homme-environnement actuel est considéré comme étant un présage de déstabilisation de la balance de l’environnement, de l’écosystème et de l’économie.

La question de la mise en protection, de la conservation et de la régénération ne date pas d’hier. En effet, plusieurs interventions ont eu lieux pour pouvoir permettre au Maroc une croissance soutenue et durable. Cependant, elles semblent à bien des égards être reprochées.

Dans le secteur du tourisme, l’appauvrissement des atouts de la biodiversité, paysagers et génétiques dû aux activités touristiques est très considérable, de ce fait, la régulation des équilibres devrait être imminente surtout suite à l’ouverture du monde rural et naturel au tourisme.

Voulant axer l’activité touristique, le développement durable et l’environnement au centre d’une politique de gestion originale et durable. Les Paiements pour Services Environnementaux sont considérés comme étant le vocable commun qui permet de tracer un enjeu collectif mobilisant différents acteurs et mariant des secteurs malgré leur divergence. C’est une nouvelle approche managériale de développement représentant un gage d’efficacité par rapport aux autres mesures de conservation et ayant des échos de réussite dans plusieurs pays du globe. Nous pouvons les considérer comme étant un nouvel parangon face aux problèmes venant pallier les limites des instruments antérieurs.

Dans notre cas, l’idée est de procréer une production monétaire au service de l’environnement et du patrimoine culturel et naturel dans un cadre touristique et durable.

De ce fait, notre fond PSE est une notion discursive qui lie plusieurs raisonnements et les rend conciliables, mais aussi, qui fait remonter une panoplie d’interrogations relatives à la détermination des acteurs concernés, au montant de financement, à la définition du service environnementale, de son bénéficiaire et de ses bénéfices… Des interrogations auxquelles nous avons apporté des éléments de réponse à travers cet article qui vise à recentrer les principes de ces procédés socioéconomique et environnemental et les converger vers une application sur le secteur touristique dans les régions rurales.
Laparoscopic cystectomy with
lymphadenectomy and ileoconduitis creation:
А case report
Authors: Kurmanov T. A. , Digay A. K. , Mugalbekov Sh. B. , Zhumagazin Zh. D. , Mukazhanov A. K. , Mustafinov D. D.
Published: October 2021

Relevance: Radical cystectomy remains the “gold standard” of treatment for muscle-invasive and locally advanced
bladder cancer. The article describes the capacity and technique of laparoscopic cystoprostatectomy with lymphadenectomy and the creation of an ileoconduitis in bladder cancer,
since the authors could not find publications on conducting
laparoscopic cystoprostatectomy with the creation of an ileoconduitis in oncological and urological clinics in Kazakhstan
by domestic specialists.
The purpose was to describe an attempt to reproduce laparoscopically the method of open radical cystectomy as accurately as possible.
Results: In the described case, the patient diagnosed with
the bladder cancer T2N0M0 IIst underwent surgery in the form
of laparoscopic cystectomy with lymphadenectomy and the creation of an ileoconduitis. This method of surgical intervention is
minimally invasive, less traumatic, and ensures quick recovery in
the postoperative period.
Conclusion: Laparoscopic execution of radical cystectomy
allows preserving the advantages of minimally invasive interventions without losing the reliability of the well-proven open
surgery. Currently, the implementation of such minimally invasive surgical interventions is possible in many clinics in Kazakhstan, equipped with endoscopic video equipment, if there are
specialists experienced in open surgery.
Method for Trifuzol-Neo assay determination by GC-MS
Authors: Yaroshenko A.A. , Parchenko V.V. , Bihdan O.A. , Panasenko O.I. , Karpenko Yu V. , Karpun E.O.
Published: October 2021

The derivatives of 1,2,4-triazole are of the great scientific interest in the fields of pharmaceutics, agricultural chemistry, and construction The production of Trifuzol-Neo has already been launched, and it is now commercially available. Compounds based on 1,2,4-triazole may also be useful in veterinary practice due to their antiviral activity. Trifuzol-Neo, or piperidinium ([5-(2-furanyl)-4-phenyl-4Н-1,2,4-triazol-3-yl]thio)acetate (Figure 1), has already proved to be an effective immunostimulator for poultry.Since that, the quality control of raw materials and the ready product is required during the production stage. Currently, there is only one method for determination of the assay of Trifuzol-Neo, which involves HPLC-DMD (Center of Medical Research Information and Patent and Licensing Practice of Ukraine. The main disadvantages of HPLC-DMD are the use of relatively high amounts of costly solvents (acetonitrile in this case), considerable baseline instability, and time-consuming system stabilization. Gas-chromatography is able to avoid these constrictions since it involves gas as a mobile phase, which is a more cost-effective and reproducible alternative. The newly developed GC/MS method for Trifuzol-Neo assay determination consists of the following steps: weighing 20.0mg of Trifuzol-Neo powder, dillution in 20mL methanol, injection of 0.5uL of the obtained solution to GC column (at least three times). The same operations are done with a Trifuzol-Neo standard.
Stability Indicating RP-UPLC Method for Simultaneous Estimation of Rabeprazole Sodium and Mosapride Citrate in Tablet Dosage form
Authors: Patel Nilesh K. , Rana Bhumika H. , Patel Dhruti M. , Vyas Amitkumar J. , Patel Ashok B. , Patel Ajay I.
Published: October 2021

RP- UPLC method was developed and validated for the simultaneous determination of Rabeprazole sodium and Mosapride citrate in tablet dosage form. The separation was achieved on a BEH C18 (50mm × 2.1mm× 1.7µm) column using mobile phase of Ammonium acetate buffer: Acetonitrile (60:40% v/v). The flow rate was 0.4 ml/min and detection was carried out at 270nm and column oven 35ºC. Rabeprazole sodium and Mosapride citrate was subjected to stress condition including Acidic, Alkaline, Oxidation, Photolysis and Thermal degradation. This method was validated as per ICH (Q2R1) guideline.
Standardization and Phytochemical screening of Carica papaya seeds
Authors: Singh Varsha , Rizvi Aleza , Singh Sara Udaivir
Published: October 2021

The present work focus to evaluate the physicochemical and preliminary phytochemical studies on the seeds of family Caricaceae. The plants resources which are used in pharmaceutical formulation standardization was carried out on the basis of organoleptic properties, physical characteristics, and physico-chemical properties. Different Physicochemical parameters ash values, extractive values, loss on drying, foreign matter, fluorescence analysis, and pH were evaluated. Macroscopical characteristics and Physicochemical parameters like total ash, acid insoluble ash and water soluble ash were found to be 83.7%, 71.7% and 61.5% w/w respectively. Hexane, ethyl acetate, ethanol and water soluble extractive values (hot)were 7.6%, 11.6%, 27.4%, 37.5%w/w respectively. The pH of 1% and 10% aqueous solution was found to be 3.57 and 3.78 respectively. Preliminary phytochemical screening showed the presence of Tannins, Proteins and amino acids, Glycosides, Phenolic compounds, Carbohydrates, Saponins, Alkaloids and Flavonoids. Thin layer chromatographic studies also had been done on ethanolic and hexane extracts. HPTLC fingerprinting is a valuable method for the quantitative determination of phytochemicals present in plant extract. These studies aim to investigating referential information for correct identification and standardization of this plant secondary metabolites.
The Isolation of specifically lytic phages along with their extracted endolysins as antibacterial agents to MDR Enterococcus faecalis
Authors: Ahmed Shaymaa Husham , Hafidh Rand R.
Published: October 2021

Background: Multidrug-resistant (MDR) enterococci have become a major problem in recent times and have been reported increasingly around the world. Lytic phages infect bacteria leading to rapid host death with limited risk of phage transduction, underlining the increasing interest in potential phage therapy in the future. Objective (s): The aim of this study is to use phage therapy as alternative approach for treatment of Enterococcus faecalis infections that recorded as MDR in Iraq to tackle this problem. Materials and Methods: Thirty E. faecalis isolates were collected from patients with different infectious diseases such as urinary tract infection (UTI), diabetic foot, septicemia, and wound infections. The isolation of specific lytic phages was from different environmental sources such as (sewage, and wastewater). The biokinetic assays were carried out to measure the characteristics of the isolated phage. The study of the bacteriophage and the formed phage cocktail infectivity against isolates E.faecalis was tested by the top layer assay. The phage endolysin was extracted from the best bacteriophage that gave best results. Results: All the isolated E.faecalis was reported as MDR in this study. About 75 E.faecalis specific phages were isolated and purified. All the isolated bacteria were 100% sensitive to the lytic phages. The formed phage cocktail was capable to create inhibition zones on the most bacterial isolates' lawns. The molecular weight and the concentration of the extracted endolysin was evaluated in this study and found to be as (48 kDa) and (0.5mg/ml), respectively. The antibacterial activity of the extracted endolysin was evaluated by the turbidity reduction assay. A clear decline in the bacterial growth was manifested (5x107 CFU/ml) to (1x104 CFU/ml), in which the bacterial growth was reduced by (3.63 log). The endolysin found to be effective against 90% of E.faeclais isolates. Conclusion: The activity of the isolated specific phage together with the activity of the formed phage cocktail, were efficient as successful and inexpensive method of therapy against MDR E.faecalis. The potential of the extracted endolysin over the phage therapy was verified in this study. The coverage rate and the absence of resistant E.faecalis to the phage and its endolysin had emphasized on the importance of this alternative therapy to commonly used antibiotics. List of abbreviation: MDR = multiple drug-resistant, E. faecalis = Enterococcus faecalis, BT = burst time, BS = burst size, IP = infective percentage, Phage =bacteriophage, CFU = Colony forming unit, kDa = Kilodalton, OD = Optical Densities.
Quantitative estimation of Silybin in Iraqi Silybum marianum by HPLC
Authors: Eldalawy Rasha , Al-Ani Widad M K , Abdul Kareem Wasan
Published: October 2021

Milk thistle's extract by an organic solvent is known as silymarin, which is a mixture of about 75% flavolignan and trace content of flavonoid (mainly taxifolin), other ingredients involve fatty acids and polyphenolic compounds. The major flavolignans are silybin, isosilybin, silydianin, and silychristin, quantitatively silybin is considered as the major compound followed by isosilybin, and both are represent approximately 60% of silymarin. This study was designed to determine the concentration of silybin in different parts of the plant and to study the effect of extraction methods, solvents and the time of collection on silybin concentration, which have been done by HPLC instrument. The results show that the higher yield of silybin is obtained from the seed using ethanol in the soxhlet apparatus and that all other parts of the plant which are produced in huge amount by the plant also contain a good concentration of silybin when compared with seeds, So they can be used as an alternative source for silybin production.
Reverse Phase High Performance Liquid Chromatographic Method for Separation and Estimation of impurities present in Pharmaceutical Formulation of Empaglifozin
Authors: Patel N , Patel S
Published: October 2021

Empaglifozin is a Sodium-glucose co-transporter-2 inhibitors work by inhibiting SGLT2, to prevent reabsorption of glucose and facilitate its excretion in urine. Impurities in pharmaceuticals which are unwanted chemicals that remain with the active pharmaceutical ingredients (APIs), or develop during stability testing, or develop during formulation or upon aging of both API and formulation. A simple and very sensitive method developed for estimation of impurities present in Empaglifozin formulation by Reverse Phase High Performance Liquid Chromatographic method. Method is capable to detect impurities in very low level (1µg/mL). Chromatographic separation of six different impurities was achieved on Inertsil ODS-2 (250 x 4.6) mm, 3µm column using gradient elution method at 30°C column temperature and the detection was carried at 230nm at a flow rate of 1.0 mL/min. The method was validated as per ICH Q2(R1) guideline along with stress studies.
Isolation and Characterization of Flavonoids of the Ethanolic extracts of stems of Mimosa hamata (Willd.) by Chromatographic techniques
Authors: Khan N.I. , Hatapakki B.C. , Tamboli A.M.
Published: October 2021

Since there are many bioactive compounds present in plant material containing various multi-component mixtures, their separation and determination is important to identify the active phytoconstituents responsible for pharmacological activity. Practically most of them have to be separated by column chromatographic techniques. The present study deals with the identification and characterization of bioactive principles from the stems of Mimosa hamata. The isolated fractions from the ethanolic extracts of stems of Mimosa hamata was carried out by column chromatography. For separation of a bioactive compound, the solvent system tried for column chromatography was Chloroform: Methanol in various ratios like 90:10, 80:20, 70:30, and 60:40 amongst these we could separate the first fraction at 80:20 and second fraction at 70:30. Two flavonoids compounds were isolated from the ethanolic extracts of stems of the medicinal plant Mimosa hamata (Willd). Based on chemical and spectral analyses their structures were elucidated as Quercetin and Cirsimaritin. From the above study it reveals the presence of flavonoids in the ethanolic extracts of stems of Mimosa hamata (Willd.) was isolated using column chromatography further subjected to characterization of isolated compounds including UV, IR, NMR and Mass spectroscopic study for elucidating the structure of the two separated compounds. The interpreted data concluded that, both isolated compounds are flavonoids i.e. Cirsimaritin and Quercetin. The pharmacological effect of Mimosa hamata stems may be due to the presence of its phytoconstituents flavonoids.
Optimization of Extraction of Curcuminoids from Turmeric Powder (Curcuma longa)
Authors: V. Vyshali , Jyotsna N. Lalitha , Bakshi Vasudha , Ismail Syed , Mohanty Dibyalochan , T. Kavitha , M. Manoj
Published: October 2021

In this study extraction of curcuminoids from turmeric was explored by various methods of extraction. For extraction soxhelet, ultrasonication and distillation methods were employed for separation of curcuminoids from turmeric powder under more or less varying same parameters. The results were analyzed and compared with reference method. The UV-Vis spectroscopy, HPLC and TLC were used for the confirmation and quantification of extract. The TLC analysis showed the three bands denoted the presence of three curcuminoids. The UV-Vis spectral analysis specified the absorption peak at 425nm. The HPLC studies implied the existence of three peaks for sonicated extract. The interpretation of the observation emphasized that the yield of extraction was higher for sonication method than remaining other extraction methods under varying parameters. Hence sonication method was considered as optimized extraction method which was time saving and less energy consuming favorable extraction method. The emphasized characteristics of improved extraction methods including cost-effectiveness (due to much saving in time and energy consumption) and environmentally benign nature make them more favourable extraction methods.