bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisa Penyajian Laporan Keuangan Berbasis ERP (SAP) dengan Metode EUCS Di PT. Central Proteina Prima
Authors: Mentari Galih , Yulfajar Amrina
Published: September 2022

The purpose of this study is to see which SAP is used to provide reports to meet financial reporting requirements, as well as how the EUCS model is used to deliver financial reports. The research approach in this case study is qualitative. Data collection was carried out at PT. Central Proteina Prima through interviews, observations, and documentation. Based on this research, the results of using SAP are considered to meet the report quality requirements.cial reports in accordance with the Indonesian Financial Accounting Standards (SAK), which include the Financial Accounting Standards of the Indonesian Institute of Accountants (DSAK Statement) of the Financial Accounting Standards (PSAK) and the Interpretation of Financial Accounting Standards (ISAK), as well as the Regulations and DSAK Guidelines.
Pengaruh Motivasi Dan Disiplin Terhadap Kinerja Karyawan Pada PT. Cilpan Finance Tanggerang II
Authors: Fadli Roni , Mulyani Sri , Setianingsih Setianingsih
Published: September 2022

The purpose of this study is to determine the effect of compensation and motivation on turnover intention at PT. Bina Putra Makmur Nusantara. This study uses quantitative methods, with a population size of 51 respondents with saturated sampling type, namely all employees at PT. Bina Putra Makmur Nusantara. Collecting data using a questionnaire distributed to employees of PT. Bina Putra Makmur Nusantara. The collected data was then analyzed using Validity Test, Reliability Test, Classic Assumption Test, Simple Linear Regression Test, Multiple Linear Regression Test, Coefficient of Determination Test and Hypothesis Testing with the help of SPSS Version 25 program. Compensation variables have a negative effect on performance at PT. Bina Putra Makmur Nusantara, based on the results of an analysis of the influence of factors that influence turnover intention, shows tcount < ttable, namely -2.720 < 2.009, sig 0.009 < probability 0.05. Motivation variable has a positive and significant effect on performance at PT. Bina Putra Makmur Nusantara, motivation variable has the most dominant influence on performance with tcount > ttable, which is 4.652 > 2.009, and sig 0.000 < probability 0.005. Compensation and motivation variables together and simultaneously have a positive and significant effect on the performance of PT. Bina Putra Makmur Nusantara, because the fcount is greater than the ftable value, namely 137,048 > 3.19 with a significant level of < 0.05, which is 0.000.
Upaya Penerapan Kelasnya Manusia dalam Meningkatkan Motivasi Belajar
Authors: Dwi Safitri Elsa , Ardi M , Eka Priyantoro Dian , Mei Ratnasari Eka
Published: September 2022

Belajar melalui bermain merupakan teknik pengajaran yang berkesan bagi anak usia dini. Teknik ini dapat mendatangkan kesenangan dan kepuasan kepada peserta didik dalam program yang hendak disampaikan. Teknik belajar melalui bermain dapat dilakukan dengan menggunakan strategi, metode, materi atau bahan, dan media yang menarik agar mudah diikuti anak. Tujuan penelitian ini dimaksudkan untuk mengetahui bagaimana penerapan kelasnya manusia dalam meningkatkan motivasi belajar di PAUD Mentari Desa Sidoluhur, Kecamatan Bangunrejo, Kabupaten Lampung Tengah. Jenis penelitian yang digunakan adalah penelitian lapangan, adapun sifat penelitian yang digunakan adalah deskriptif kualitatif, dengan menggunakan sumber data primer dan sekunder berupa dokumen-dokumen yang berada di lembaga. Teknik pengumpulan data yang digunakan adalah wawancara, observasi, dan dokumentasi. Wawancara dilakukan kepada kepala sekolah, guru, dan wali murid, sedangkan observasi dilakukan untuk mengamati bagaimana keadaan proses belajar dan lembaga pendidikan tersebut. Serta dokumentasi digunakan sebagai pelengkap guna memperoleh data sebagai bahan informasi yang berupa data-data program yang ada. Pembelajaran dengan kelasnya manusia dapat meningkatkan motivasi belajar peserta didik, karena dengan display yang menarik akan memotivasi belajar peserta didik dan pembelajaran akan tersampaikan dengan baik. Faktor pendukung penerapan kelasnya manusia yaitu memanfaatkan barang-barang yang dapat dimanfaatkan kembali serta memiliki lingkungan yang mendukung dalam menunjang pembelajaran kelasnya manusia tersebut.
Modifikasi Intelegensi dan Berpikir Kritis dalam Memecahkan Masalah
Authors: Fauziah Erna , Kuntoro Tri
Published: September 2022

Tujuan penelitian ini adalah untuk menganalisis kemampuan pemecahan masalah matematik dan respon mahasiswa terhadap pembelajaran matematika melalui media pembelajaran  Games Asah Otak Modifikasi Berpikir Kritis. Penelitian ini dilaksanakan di Brain Academy Ruangguru Duren Sawit Jakarta Timur. Metode penelitian yang digunakan adalah quasi-eksperimen dengan desain penelitian Two Group Randomized Subject Posttest Only Design dengan tambahan hasil observasi. Subyek penelitian berjumlah 65 siswa, 35 siswa kelas eksperimen dan 30 siswa kelas kontrol yang diperoleh dengan teknik cluster random sampling. Kemampuan Pemecahan dan respon siswa diukur dengan menggunakan observasi, angket dan test. Hasil penelitian mengungkapkan bahwa secara deskripsi, media pembelajaran Games Asah Otak Modifikasi Berpikir Kritis berpengaruh terhadap kemampuan pemecahan masalah matematik. kemampuan pemecahan masalah matematik yang diajarkan dengan media pembelajaran Games Asah Otak Modifikasi Berpikir Kritis lebih baik daripada siswa yang diajarkan dengan cara biasa. Siswa menunjukkan respon positif yang sangat kuat terhadap penggunaan media pembelajaran Games Asah Otak Modifikasi Berpikir Kritis dalam pembelajaran matematika.
Effect of Personality Traits on Investment Intention of People: Kazakhstan Case
Authors: Sadykov Olzhas
Published: September 2022

The paper aims to study relationship between personality traits (“big five” traits, such as openness, conscientiousness, extraversion, neuroticism, and agreeableness), as well as financial literacy of retail investors on willingness to make investment decisions on financial assets in Kazakhstan. Survey collection method of 200 randomly selected people from different social statuses, geographical locations (cities, countryside) and ages via internet, printed papers, and face-to-face meetings. There were decided to approach exploratory study with pragmatic philosophical view. Due to the reason of usage questionnaire, quantitative approach will be the most suitable approach for the study. The research is tended to be completed during the one academic semester. Hence, cross-sectional study is the best fitted type of study for the research paper. Salary, extraversion, agreeableness, preferences on investment instruments and level of financial literacy have statistically significant positive impact on intention of people to participate in investment activities. Conversely, openness trait found to has statistically significant negative impacts on investment intention of participants. Other variables do not have a statistically significant negative or positive impacts on investment willingness within the country. Intention to make investment decisions can be identified by screening of secondary data received from related papers, intention to make risky investments and level of risk tolerance toward investment decisions. However, level of tolerance toward risks varies according to the individuals' level of neuroticism, agreeableness, as well as level of sadness, conscientiousness, and financial literacy.
The Effect of Supply Chain Management on Competitive Advantage: Mediating Role of Supply Chain Responsiveness in Ethiopian Food Processing Industry
Authors: Nigatu Habtemariyam Tilahun , Amentie Kero Chalchissa
Published: September 2022

This study aims to examine the indirect impact of supply chain management (SCM) in its five dimensions (supplier relationship, customer relationship, information sharing, information quality and postponement) on the competitive advantage in its five dimensions (Cost, Quality, Delivery Time, flexibility, and innovation) through supply chain responsiveness as a mediator. Furthermore, 234 questionnaires were distributed in food processing industries. The total of 215 questionnaires was analyzed. For a robust result, we conducted exploratory factor analysis (EFA) using Varimax rotation and confirmatory factor analysis (CFA) to check the scale. Furthermore, we test validation of the second-order construct. Structural equations modelling (SEM) using AMOS 24 was used to test the hypotheses. The results of analysis show that the supply chain management practice (SCMP) has a positive and statistically significant influence on supply chain responsiveness (β = 0.909, p-value = 0.000) and the competitive advantage of firms with the standardized coefficient of (β= 0.639, p-value = 0.000). Similarly, the supply chain responsiveness has a positive and significant effect on competitive advantage by (β = 0.352, p-value = 0.000), on the other hand, supply chain management practice (SCMP) has a significant indirect effect on competitive advantage by (β = 0.320, p-value = 0.000) through supply chain responsiveness. Accordingly, we suggest that managers of food processing should properly manage their supply chain management practice, develop a responsive supply chain to gain a competitive advantage. But this study was limited only to food processing with plc and Share Company.
Barriers of Good Corporate Governance Practices: Evidence from Emerging Economy
Authors: Liu Yin
Published: September 2022

Corporate governance (CG) is often split among rule and principle-based methods to regulation in distinctive institutional contexts. CG practices are divergent among countries due to differences in their institutional environments. Therefore, the purpose of this study is to identify the barriers of CG practices and compliance in Pakistan. The primary data is collected from 105 Pakistan Stock Exchange (PSX) listed firms through survey questionnaire. The study employed the exploratory factor analysis (EFA) to identify the barriers of good CG practices and compliance in Pakistan.

Using exploratory factor analysis (EFA), this study identified five major barriers, i.e. firm level barriers (lack of auditor independence, board ineffectiveness, lack of shareholders’ awareness), external barriers (political and governmental interference in business activities, weak legal control and enforcement, high levels of corruption), social barriers (strong social ties among different stakeholders, interpersonal connections among boards of directors (BoDs), education and training barriers (lack of professional education and training among stakeholders) and legal barriers (fewer voting rights) which restrain good CG practices in Pakistan.

The study contributes to existing CG literature and highlights the barriers which hinder the good CG practices and compliance, especially in the context of Pakistan. The findings are applicable to other emerging markets especially in Asian countries due to similar socio-economic environment.
Macht Putin den (Neo-)Realismus stark?
Authors: Zürn Michael
Published: September 2022

Roland Czada fordert in seinem Leviathan-Beitrag, dem (neo)-realistischen Paradigma in den Internationalen Beziehungen den ihm zustehenden Raum zu geben. Der „normative Institutionalismus“ - so der Name des imaginierten Gegners - beruhe auf naiven Annahmen und führe die Politik in die Irre. Wenn man die Lakatos-Kriterien für ein progressives Forschungsprogramm heranzieht, ergibt sich ein anderes Bild. Das (neo-)realistische Forschungsprogramm erklärt den russischen Angriff auf die Ukraine kaum, hat Schwierigkeiten, die Reaktionen auf diesen Krieg zu verstehen, und bleibt bei vielen anderen wichtigen Fragen der Weltpolitik seltsam leise. Auch kann man nicht darauf bauen, dass eine (neo-)realistisch angeleitete Politik klüger wäre, weil die Verbindung von Theorie und ihren realen politischen Empfehlungen nur sehr lose ist.
Digitalisieren und zugänglich machen! Rechtliche und kulturethische Aspekte im Umgang mit historischen Klangaufnahmen des Berliner Phonogramm-Archivs
Authors: Kirchmair Lando
Published: September 2022

Die Restitutionsdebatte ist von großer gesellschaftlicher Bedeutung; einen juristischen, moralischen und politischen Königsweg scheint es indes nicht zu geben. Dieser Beitrag beleuchtet die bisher wenig beachteten, als Weltdokumentenerbe ausgezeichneten Bestände des Berliner Phonogramm-Archivs. Sie enthalten historische Klangaufnahmen aus aller Welt, die, so das Plädoyer dieses Beitrags, digitalisiert und sodann Open Access der Weltöffentlichkeit zur Verfügung gestellt werden sollten.
Der Einfluss der Corona-Pandemie auf den niedersächsischen Strafvollzug aus Sicht der Anstaltsleitungen
Authors: Schüttler Helena , Neumann Merten , Henningsmeier Isabel , Tischmeyer Tiffany
Published: September 2022

Die Corona-Pandemie hat den Strafvollzug - und die Anstaltsleitungen als zentrale Entscheidungsinstanz - vor besondere Herausforderungen gestellt. Im Rahmen des Forschungsprojektes „Corona Behind Bars (CoBiBar)“ werden die Auswirkungen der Corona-Pandemie für die Anstaltsleitungen, die Mitarbeitenden des allgemeinen Vollzugsdienstes sowie die Gefangenen umfassend untersucht. In dem vorliegenden Beitrag werden die ministeriellen Vorgaben, Veränderungen und Maßnahmen aus Sicht von sechs Anstaltsleitungen in Niedersachsen betrachtet. Die Ergebnisse zeigen auf, dass eine Vielzahl von Maßnahmen und Einschränkungen getroffen wurden, um einer Ausbreitung des Coronavirus entgegenzutreten. Gleichzeitig wurden ausgleichende Maßnahmen (u. a. das Angebot der Videotelefonie oder eine Erweiterung der Telefonzeit) zur Verfügung gestellt. Die umgesetzten Einschränkungen wurden vor allem zu Beginn der Pandemie als stark eingeschätzt. Dies spiegelt sich auch in der Bewältigung der Wellen wider, wobei sich hier die Wahrnehmung zwischen den Anstalten deutlich unterscheidet. Neben einem erhöhten Zeitaufwand wurde der Anstieg der Krankheitsfälle sowie eine gesteigerte Unzufriedenheit des Personals als Folgen der Pandemie angegeben. Die Auswirkungen der Corona-Pandemie auf Mitarbeitende und Inhaftierte werden in den noch folgenden Teilschritten des Projektes umfassend beleuchtet.
Investigation of Association Between Insulin Injection Technique and Blood Glucose Control in Patients with Type 2 Diabetes
Authors: Mehrabbeik Akram , Namiranian Nasim , Azizi Reyhaneh , Aghaee Meybody Mohammadreza , Shariati Mahbobeh , Mahmoudi Kohani Hassan Ali
Published: September 2022

Background: The appropriate insulin injection skill is essential for optimal blood sugar control in patients with diabetes. However, the art of insulin injection is still not well understood in numerous medical centers. Objectives: This study was designed to determine the association between appropriate insulin injection and blood glucose control in patients with type 2 diabetes in Yazd, Iran. Methods: This cross-sectional study was conducted on 301 patients with type 2 diabetes who referred to Diabetes Research Center in Yazd within August 2020 to February 2021. Based on simple random sampling, the subjects with inclusion criteria, such as age >18 years, using an insulin pen for at least 3 months, and self-injection, were selected. The insulin injection technique was evaluated by a 13-item researcher-made questionnaire. The total score of this questionnaire was 26, and its validity and reliability were confirmed. The data were analyzed using SPSS software (version 20). Results: The mean age of the participants was 59.83 ± 10.26 years, and 60.1% had primary school or less education. Most participants (87%) used a needle more than five times, and almost half of them (53.5%) did not rotate the injection sites properly. The patients who reported pain during injection had statically lower injection scores than others (17.90 vs. 19.38, P = 0.001). There was a significant negative correlation between insulin injection score with fasting blood sugar (β = -0.232, P < 0.001), two-hour postprandial glucose (β = -0.164, P = 0.005), and hemoglobin A1c (HbA1c) level (β = -0.263, P < 0.001). Conclusions: None of the patients in this study fully followed the principles of a proper injection, which can lead to pain during injection, lipohypertrophy, hyperglycemia, and increased HbA1c levels.
Exploring Challenges and Needs of Parents Providing Care to Children with Autism Spectrum Disorders: A Qualitative Study
Authors: Hosseinpour Amirhossein , Younesi Seyed Jalal , Azkhosh Manoochehr , Safi Mohammad Hadi , Biglarian Akbar
Published: September 2022

Background: The circumstances and needs of children with autism spectrum disorder (ASD) affect children and their families. Objectives: This study aimed to explore the challenges and needs of parents caring for children with ASD. Methods: An exploratory qualitative method and the conventional content analysis method were employed in the present study. Participants were 18 parents with children with ASD in Tehran who were recruited by the accessible sampling method. To collect data, semi-structured, face-to-face, and in-depth interviews were used. The interviews were audio-recorded and transcribed verbatim into Microsoft Word software. Qualitative analysis was performed using the content analysis approach. Results: Parents had three main needs in caring for their children: (1) first, issues and problems related to diagnosis, treatment, and rehabilitation, including three categories (issues and problems of diagnosis and treatment, issues and problems of rehabilitation, and inadequate therapeutic support); (2) second, issues and problems related to parents, including four categories (parents’ lack of knowledge and awareness about ASD, lack of life skills, daily problems of parenting, and familial & marital issues); and (3) third, financial, cultural, and social issues, including two categories (financial problems and social & cultural problems). Conclusions: The needs and challenges mentioned by the parents of children with ASD highlighted the need for medical, educational, and counseling services and emotional and material support from the community and the government. Planning and implementing support programs enable parents to face problems strategically, which ultimately improves their quality of life.
Is There Any Difference Between Maneuver Simulation and Scenario Workshop Learning about Radiation Triage?
Authors: Delsooz Mostafa , Mazloum Seyed Reza , Mirhaghi Amir
Published: September 2022

Background: Very little information on maneuver simulations (MS) effectiveness in radiation triage (RT) training is currently available. Objectives: The present study aimed to compare the effect of MS and scenario workshops (SW) on rescuers' learning of RT. Methods: This quasi-experimental study was conducted on rescuers in July 2020. For this purpose, two military medical centers were randomized into two groups, intervention (MS) and control (SW). The main tool was the researcher-made Radiation Triage Knowledge Questionnaire (RTKQ). In this respect, the pre-test was performed using the RTKQ questionnaire. The first post-test, two weeks following the intervention, was also done through the RTKQ and the objective structured clinical examination (OSCE), and the second post-test was conducted four weeks after the intervention, only via the RTKQ. Results: In total, 30 rescuers with a mean age of 22 participated in this study. During the pre-test, the difference in knowledge between the two study groups (intervention and control) was not significant. In the first post-test, no significant difference was also observed in the levels of knowledge between MS and SW groups respectively (80.0 ± 8.9 vs. 79.3 ± 0.8), but the difference in skills between the study groups was significant (89.3 ± 10.3 vs. 61.3 ± 16.0). In the second post-test, there was a significant difference between the mean value of the levels of knowledge (76.0 ± 9.1 vs. 64.7 ± 10.9) and skills (written scenarios) (71.3 ± 9.9 vs. 54.0 ± 0.14) in two study groups. Conclusions: Both training methods improved RT knowledge and skills, but MT was more effective than SW in boosting and maintaining knowledge and skills up to one month after the intervention. The utilization of MS in RT training was also accompanied by greater effectiveness.
What is the Meaning of Beauty’s Leading Us before the Face of God?
Authors: Ramos Alice M. ,   Philosophy Documentation Center
Published: September 2022

For Dietrich von Hildebrand beauty invites us to transcendence and leads us before the face of God, or in conspectu Dei. In order to elucidate what this means attention will be focused first on the objective importance of beauty, which carries with it according to von Hildebrand a message such that it speaks to us. The meaning of beauty as a “word” needs to be grounded in a metaphysics of the Logos which is in fact Light and Beauty, making everything a participant in its light and beauty. If beauty as that which is important in itself or as value speaks to us, then a response is needed on our part, but responses to beauty can vary as von Hildebrand indicates in distinguishing between appropriate and inappropriate responses; why this is so will occupy briefly the second part of this paper. And lastly, the “call” of beauty to us is related to the final perfection of the human person, where true identity is achieved and where we will at last stand before the face of God.
Aquinas on Bodily or Sensible Beauty
Authors: Rubin Michael J. ,   Philosophy Documentation Center
Published: September 2022

Thomas Aquinas consistently maintains that there are two kinds of beauty: bodily or sensible beauty and spiritual or intelligible beauty. Due to the lively debate over whether intelligible beauty is a transcendental for Thomas, discussions of his aesthetics have tended either to ignore his views on sensible beauty or to mention them only in passing. The present paper will therefore give a brief overview of Thomas’s thought on bodily beauty. The first section will discuss the objective aspects of sensible beauty for Thomas, i.e., its definition and three conditions, while the second will present his views on its subjective aspects, i.e., how we experience it, why it pleases us, and its importance for human flourishing. The third and final section will examine how Thomas’s account of sensible beauty affects his views on the beauty of the glorified human body and of the universe as a whole after the Last Judgment.
Students of Revolution: An Essay on Ali Shariati’s Counter-Pedagogy
Authors: Mansoori Naveed ,   Philosophy Documentation Center
Published: September 2022

Though Ali Shariati is well-known as the “ideologue” of the Islamic Revolution of Iran, this essay considers Shariati conversely as a student of revolution. It begins by posing a distinction between the apprentice and the autodidact through reference to Ibn Tufayl’s Hayy ibn Yaqzan and introduces a third term, the collaborator, that is crucial to Shariati’s account of counter-pedagogy. The essay then reconstructs Shariati’s critique of the pedagogical state. There, he recalls resisting interpellation by learning from other pasts, refusing instruction, and learning from others. Finally, I show changes in how Shariati conceptualized self-transformation, from an autodidactic process of soul-searching to a collaborative process that gives soul to a collective. On becoming immersed in the sounds of his compatriots grieving the martyrs of struggle, Shariati attests to being a student of history: the curriculum of a people becoming, the history of struggle, and its instructors, those who modeled it, pivoted around a refusal to be instructed. Overall, this essay develops an account of media environments as informal pedagogical spaces.
The Search for God in the works of A. Hitchcock and I. Bergman
Authors: Popova Liana
Published: September 2022

The subject of this article is the work of A. Hitchcock and I. Bergman, which are well studied both in Russia and abroad. The relevance of this study is due to the fact that so far no attempt has been made among researchers to investigate the influence of A. Hitchcock's work on I. Bergman. The purpose of this study is a comparative analysis of the work of A. Hitchcock and I. Bergman, identifying similarities and differences, including in matters of religious faith; studying such a little-known aspect as the influence of A. Hitchcock on the work of I. Bergman. The author also pays attention to the consideration of the religious views of A. Hitchcock, to which the researchers paid little attention. This study uses an integrated approach, including a comparative method for analyzing the connections between directors, a phenomenological method, as well as a method of psychoanalysis in their combination and complementarity. The novelty of this research consists in identifying the links between directors, in applying an integrated approach to the analysis of their works. The conclusion is made about the religious views of A. Hitchcock and I. Bergman, their similarities and differences. Bergman's religious views underwent a long transformation throughout his life. Hitchcock's religious views were more conservative and stable, which affects the rhythm of his paintings.
Rethinking the representation of sound
Authors: Bola Łukasz
Published: September 2022

Blindness triggers a reorganization of the visual and auditory cortices in the brain.
Atavismo religioso, sacrificios humanos y defensa cultural: el caso Painecura (1962)
Authors: Céspedes Rodrigo , Al Fakih Fátima
Published: September 2022

En 1960 se produjo un mega-terremoto que produjo además un maremoto de grandes proporciones. Una comunidad mapuche realizó un sacrificio humano para calmar a la naturaleza y detener la catástrofe. El Tribunal absolvió a los imputados por miedo insuperable impulsado por una fuerza irresistible, procedimiento en el cual el aspecto cultural jugó un rol relevante.
Supraventricular Tachycardia Following Mitral Valve Surgery
Authors: Carbone Vincenzo , Carbone Giovanni , Cassese Antonio
Published: September 2022

A man in his mid-50s with a history of mitral valve repair presented to the emergency department with complaints of recent-onset palpitation. The QRS complexes displayed pairs of beats exhibiting complete right bundle branch block and QRS duration of 140 milliseconds followed by a third beat with normal configuration and QRS duration of 70 milliseconds. What would you do next?
Semen Quality Following Long-term Occupational Exposure to Formaldehyde in China
Authors: Lv Mo-qi , Wang Hai-xu , Yang Yan-qi , Sun Rui-fang , Ge Pan , Zhang Jian , Zhao Wen-bao , Han Shui-ping , Zhou Dang-xia
Published: September 2022

Importance

The potential effects of long-term occupational exposure to formaldehyde (FA) on human semen quality is not clear.

Objective

To assess whether long-term occupational exposure to FA is associated with semen quality.

Design, Setting, and Participants

This population-based cohort study was conducted from June 1 to June 30, 2021, in Xi’an, China. Participants were adults aged 23 to 40 years who had lived in the study area for 24 months or longer. Data analysis was performed from September 1 to October 1, 2021.

Exposures

Long-term occupational exposure to FA was measured using a formaldehyde detector, and the FA exposure index (FEI) was calculated as follows: FEI = final concentration of FA (mg/m3) × work time during a workday (hour) × cumulative workdays (year).

Main Outcomes and Measures

Semen samples were collected by masturbation after 3 to 7 days of abstinence and were then assessed by the computer-automated semen analysis system, Baso-Papanicolaou staining, and sperm-chromatin structure assay.

Results

A total of 205 men (mean [SD] age, 29.49 [3.64] years), with 124 individuals in the FA exposure group (mean [SD] FEI, 73.72 [54.86]) and 81 age-matched controls, were included in the final analysis. Long-term personal occupational exposure to FA was significantly associated with poor semen quality. Specifically, a 1-unit increase in FEI was associated with a change of −0.99% (95% CI, −1.00% to −0.98%) in total sperm motility, −0.99% (95% CI, −0.99% to −0.97%) in progressive sperm motility, −0.05% (95% CI, −0.08% to −0.02%) in curvilinear velocity, −0.07% (95% CI, −0.10% to −0.04%) in straight line velocity, −0.07% (95% CI, −0.10% to −0.04%) in time-average velocity, −0.98% (95% CI, −0.99% to −0.93%) in normal sperm morphology, −0.24% (95% CI, −0.35% to −0.11%) in seminal neutral glucosidase, −0.61% (95% CI, −0.66% to −0.56%) in seminal plasma zinc, 0.52% (95% CI, 0.15% to 1.02%) in beat cross frequency, and 0.10% (95% CI, 0.06% to 0.14%) in the DNA fragmentation index. These associations remained significant after adjusting for confounding factors. Furthermore, subgroup analysis found that high levels of oxidative stress might promote the associations between FA exposure and semen quality.

Conclusions and Relevance

This study found an association between long-term occupational exposure to FA and semen quality. This deterioration was dose and time dependent and might be induced by oxidative stress.
Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post–COVID-19 Conditions
Authors: Wang Siwen , Quan Luwei , Chavarro Jorge E. , Slopen Natalie , Kubzansky Laura D. , Koenen Karestan C. , Kang Jae Hee , Weisskopf Marc G. , Branch-Elliman Westyn , Roberts Andrea L.
Published: September 2022

Importance

Few risk factors for long-lasting (≥4 weeks) COVID-19 symptoms have been identified.

Objective

To determine whether high levels of psychological distress before SARS-CoV-2 infection, characterized by depression, anxiety, worry, perceived stress, and loneliness, are prospectively associated with increased risk of developing post–COVID-19 conditions (sometimes called long COVID).

Design, Setting, and Participants

This prospective cohort study used data from 3 large ongoing, predominantly female cohorts: Nurses’ Health Study II, Nurses’ Health Study 3, and the Growing Up Today Study. Between April 2020 and November 2021, participants were followed up with periodic surveys. Participants were included if they reported no current or prior SARS-CoV-2 infection at the April 2020 baseline survey when distress was assessed and returned 1 or more follow-up questionnaires.

Exposures

Depression, anxiety, worry about COVID-19, perceived stress, and loneliness were measured at study baseline early in the pandemic, before SARS-CoV-2 infection, using validated questionnaires.

Main Outcomes and Measures

SARS-CoV-2 infection was self-reported during each of 6 monthly and then quarterly follow-up questionnaires. COVID-19–related symptoms lasting 4 weeks or longer and daily life impairment due to these symptoms were self-reported on the final questionnaire, 1 year after baseline.

Results

Of 54 960 participants, 38.0% (n = 20 902) were active health care workers, and 96.6% (n = 53 107) were female; the mean (SD) age was 57.5 (13.8) years. Six percent (3193 participants) reported a positive SARS-CoV-2 test result during follow-up (1-47 weeks after baseline). Among these, probable depression (risk ratio [RR], 1.32; 95% CI = 1.12-1.55), probable anxiety (RR = 1.42; 95% CI, 1.23-1.65), worry about COVID-19 (RR, 1.37; 95% CI, 1.17-1.61), perceived stress (highest vs lowest quartile: RR, 1.46; 95% CI, 1.18-1.81), and loneliness (RR, 1.32; 95% CI, 1.08-1.61) were each associated with post–COVID-19 conditions (1403 cases) in generalized estimating equation models adjusted for sociodemographic factors, health behaviors, and comorbidities. Participants with 2 or more types of distress prior to infection were at nearly 50% increased risk for post–COVID-19 conditions (RR, 1.49; 95% CI, 1.23-1.80). All types of distress were associated with increased risk of daily life impairment (783 cases) among individuals with post–COVID-19 conditions (RR range, 1.15-1.51).

Conclusions and Relevance

The findings of this study suggest that preinfection psychological distress may be a risk factor for post–COVID-19 conditions in individuals with SARS-CoV-2 infection. Future work should examine the biobehavioral mechanism linking psychological distress with persistent postinfection symptoms.
Real-time Tracking and Classification of Tumor and Nontumor Tissue in Upper Gastrointestinal Cancers Using Diffuse Reflectance Spectroscopy for Resection Margin Assessment
Authors: Nazarian Scarlet , Gkouzionis Ioannis , Kawka Michal , Jamroziak Marta , Lloyd Josephine , Darzi Ara , Patel Nisha , Elson Daniel S. , Peters Christopher J.
Published: September 2022

Importance

Cancers of the upper gastrointestinal tract remain a major contributor to the global cancer burden. The accurate mapping of tumor margins is of particular importance for curative cancer resection and improvement in overall survival. Current mapping techniques preclude a full resection margin assessment in real time.

Objective

To evaluate whether diffuse reflectance spectroscopy (DRS) on gastric and esophageal cancer specimens can differentiate tissue types and provide real-time feedback to the operator.

Design, Setting, and Participants

This was a prospective ex vivo validation study. Patients undergoing esophageal or gastric cancer resection were prospectively recruited into the study between July 2020 and July 2021 at Hammersmith Hospital in London, United Kingdom. Tissue specimens were included for patients undergoing elective surgery for either esophageal carcinoma (adenocarcinoma or squamous cell carcinoma) or gastric adenocarcinoma.

Exposures

A handheld DRS probe and tracking system was used on freshly resected ex vivo tissue to obtain spectral data. Binary classification, following histopathological validation, was performed using 4 supervised machine learning classifiers.

Main Outcomes and Measures

Data were divided into training and testing sets using a stratified 5-fold cross-validation method. Machine learning classifiers were evaluated in terms of sensitivity, specificity, overall accuracy, and the area under the curve.

Results

Of 34 included patients, 22 (65%) were male, and the median (range) age was 68 (35-89) years. A total of 14 097 mean spectra for normal and cancerous tissue were collected. For normal vs cancer tissue, the machine learning classifier achieved a mean (SD) overall diagnostic accuracy of 93.86% (0.66) for stomach tissue and 96.22% (0.50) for esophageal tissue and achieved a mean (SD) sensitivity and specificity of 91.31% (1.5) and 95.13% (0.8), respectively, for stomach tissue and of 94.60% (0.9) and 97.28% (0.6) for esophagus tissue. Real-time tissue tracking and classification was achieved and presented live on screen.

Conclusions and Relevance

This study provides ex vivo validation of the DRS technology for real-time differentiation of gastric and esophageal cancer from healthy tissue using machine learning with high accuracy. As such, it is a step toward the development of a real-time in vivo tumor mapping tool for esophageal and gastric cancers that can aid decision-making of resection margins intraoperatively.
Promoting endoscopists' health through cutting-edge motion analysis technology: Accuracy and precision of ergonomic motion tracking system for endoscopy suite (EMTES)
Authors: Ono Hiroaki , Hori Yasuki , Tsunemi Mafu , Matsuzaki Ippei , Hayashi Kazuki , Kamijima Michihiro , Ebara Takeshi
Published: September 2022

Objectives

Endoscopists often suffer from musculoskeletal disorders due to posture-specific workloads imposed by precise maneuvering or long procedural duration. An ergonomic motion tracking system for endoscopy suite (EMTES) was developed using Azure Kinect sensors to evaluate the occlusion, accuracy, and precision, focusing mainly on upper and lower limb movements.

Methods

Three healthy male participants pointed the prescribed points for 5 s on the designated work envelopes and their coordinates were measured. The mean occlusion rate (%) of the 32 motion tracking landmarks, standard deviation (SD) of distance and orientation, and partial regression coefficient (β) and R2 model fit for accuracy were calculated using the time series of coordinates data of the upper/lower limb movements.

Results

The mean occlusion rate was 5.2 ± 10.6% and 1.6 ± 1.4% for upper and lower limb movements, respectively. Of the 32 landmarks, 28 (87.5%) had occlusion rates of 10% or less. The mean SDs of 4.2 mm for distance and 1.2° for orientation were found. Most of the R2 values were over 0.9. In the case of right upper/lower limb measurement for orientation, β coefficients ranged from 0.82 to 1.36.

Conclusion

EMTES is reliable in calculating occlusion, precision, and accuracy for practical motion-tracking measurements in endoscopists.
Dynamic FDG‐PET demonstration of functional brain abnormalities
Authors: Quigg Mark , Kundu Bijoy
Published: September 2022

Positron emission tomography with fluorine‐18 fluorodeoxyglucose (18F‐FDG‐PET) has been used over 3 decades to map patterns of brain glucose metabolism to evaluate normal brain function or demonstrate abnormalities of metabolism in brain disorders. Traditional PET maps patterns of absolute tracer uptake but has demonstrated shortcomings in disorders such as brain neoplasm or focal epilepsy in the ability to resolve normally from pathological tissue. In this review, we describe an alternative process of metabolic mapping, dynamic PET. This new technology quantifies the dynamics of tracer uptake and decays with the goal of improving the functional mapping of the desired metabolic activity in the target organ. We discuss technical implementation and findings of initial pilot studies in brain tumor treatment and epilepsy surgery.
Relation of nonlinear oscillator design based on phase reduction method and fractional derivative
Authors: Hongu Junichi , Iba Daisuke
Published: September 2022

For wide application of the synchronization properties of nonlinear oscillators in control and signal processing engineering field, a common design method for nonlinear oscillator models is required. The output response of a nonlinear oscillator excited by a periodic signal implicitly includes information on both the instantaneous phase and the amplitude of the input signal. The design of a nonlinear oscillator model that can synchronize with an arbitrary cyclic phenomenon can be enabled by explicitly expressing the dynamics of both phase and amplitude with the phase reduction method and organizing them by the number of events in one period. Assuming the cyclic phenomenon to be a single periodic signal, the properties of the generalized nonlinear oscillator model depend on the phase resolution of the signal, which is associated with the phase‐shift of fractional calculus. Thus, this study verifies the validity of fractional calculus through the input‐output characteristic of the generalized nonlinear oscillator model. Numerical simulation using a fractional differentiator with backward‐difference demonstrated that increasing the phase resolution of a single periodic signal improves the estimation accuracy of the phase and amplitude of the signal by employing a generalized nonlinear oscillator model.
Alkaline‐Earth‐Metal‐Ions Blending Enhanced Self‐Activated and Bi3+‐Activated Mechanoluminescence from Ca1‐xBaxZnOS
Authors: Jia Jingna , Gao Xuwen , Zou Guizheng
Published: September 2022

The self‐activated mechanoluminescence (ML) of oxysulfides MZnOS (M = Ca, Sr, Ba) is very weak, and bright ML from these hosts is usually achieved with activator‐doping strategy. Herein, a promising alkaline‐earth‐metal‐ion blending strategy, instead of activator doping, is proposed to achieve intense and self‐activated ML from MZnOS. Upon partially substituting the Ca2+ of CaZnOS with Ba2+ and vice versa, intense and eye‐visible ML is achieved via exerting a small mechanical stimulus of 2 N onto the obtained Ca1‐xBaxZnOS (0 < x < 1). The luminescence center for ML of Ca1‐xBaxZnOS is intrinsic oxygen vacancy, so that Ca1‐xBaxZnOS can give off efficient and self‐activated ML. Under optimum conditions, the maximum ML emission of Ca0.84Ba0.16ZnOS is about 50‐folds and 170‐folds to that of CaZnOS and BaZnOS, respectively. Promisingly, Bi3+ can be incorporated into the lattice of Ca1‐xBaxZnOS, transferring ML center from the oxygen defects of Ca1‐xBaxZnOS to the activator of Ca0.96‐xBaxZnOS:Bi0.04, and eventually enable further enhanced ML by about twofolds. This alkaline‐earth‐metal‐ion blending strategy can also enhance Bi3+‐activated ML from M0.96ZnOS:Bi0.04, the maximum emission for ML of Ca0.80Ba0.16ZnOS:Bi0.04 is 36‐folds and 38 folds to that of Ca0.96ZnOS:Bi0.04 and Ba0.96ZnOS:Bi0.04, respectively. This work opens an avenue to develop new ML hosts and luminophores with efficient emission.
Magnetized Microcilia Array‐Based Self‐Powered Electronic Skin for Micro‐Scaled 3D Morphology Recognition and High‐capacity Communication
Authors: Zhou Qian , Ji Bing , Hu Fengming , Dai Ziyi , Ding Sen , Yang Hao , Zhong Junwen , Qiao Yancong , Zhou Jianhua , Luo Jianyi , Zhou Bingpu
Published: September 2022

Electronic skin (e‐skin), which mimics the tactile perception as human skin, is of interest to advance robotics, prosthetics, and human‐machine interactions (HMI). However, the construction of artificial e‐skin with the simulated function of morphology recognition and stimuli response remains challenging. Here, the design of a multifunctional and self‐powered e‐skin system based on the whisker‐like magnetized micro‐cilia array (MMCA) and the underneath flexible coils is reported. Owing to the excellent flexibility of the MMCA, the adaptive micro‐cilia bending can be produced according to the tactile inputs or surface morphologies. With built‐in magnetic moments, the MMCA deformation thus alters the magnetic flux distribution, which induces an electromotive force (voltage) in the coils for pressure detection and quantitative recognition of micro‐scaled 3D morphologies. It is shown that using the distinct voltage intensities and waveforms, the optimized e‐skin can be applied for real‐time healthcare monitoring, Braille identification, and reconstruction of relief information. By customizing the magnetic moment alignments in MMCA, one e‐skin device can further produce distinguishable signals to build up multi‐commands for efficient HMI, e.g., underwater Morse code communication. Along with temperature tolerance and environmental immunity, the e‐skin exhibits the potential to serve as an effective channel for intelligent 3D topology recognition and high‐capacity communications.
Perovskite‐Socketed Sub‐3 nm Copper for Enhanced CO2 Electroreduction to C2+
Authors: Li Yuxi , Liu Fuzhu , Chen Zitao , Shi Lei , Zhang Zhenbao , Gong Yue , Zhang Yu , Tian Xuezeng , Zhang Yu , Qiu Xiaoyu , Ding Xiangdong , Bai Xuedong , Jiang Heqing , Zhu Yongfa , Zhu Jiawei
Published: September 2022

In situ socketing metal nanoparticles onto perovskite oxides has shown great potential in heterogeneous catalysis, but its employment in boosting ambient CO2 electroreduction (CER) is unexplored. Here, a CER catalyst of perovskite‐socketed sub‐3 nm Cu equipped with strong metal–support interactions (SMSIs) is constructed to promote efficient and stable CO2‐to‐C2+ conversion. For such a catalyst, plentiful sub‐3 nm ellipsoid Cu particles are homogeneously and epitaxially anchored on the perovskite backbones, with concomitant creation of significant SMSIs. These SMSIs are able to not only modulate electronic structure of active Cu and facilitate adsorption/activation of key intermediates, but also to strengthen perovskite–Cu adhesion and intensify resistance to structural degradation. Beneficial from these advantageous merits, when evaluated in CER, it performs comparably to or better than most reported Cu‐based heteronanostructures. Relative to a physical‐mixture counterpart, it features marked improvements (up to 6.2 folds) in activity and selectivity for C2+, together with greatly boosted stability (>80 h). This work gives a new avenue to rationally design more advanced Cu‐based heteronanostructures for CER.
High Hysteresis Suspended Wetting State: A Wetting Regime for Controlled Trapping of Drops on Micro‐Trench Covered Surfaces
Authors: Rajak Anil , Rühe Jürgen
Published: September 2022

Wetting of simple liquids on rough surfaces is usually described either by the Cassie–Baxter model where drops are suspended over the roughness features with air trapped below, or by the Wenzel model where the drops are impaled on the roughness features. According to the Wenzel model, drops can be trapped on the surfaces, whereas in the Cassie–Baxter model, the drops can be easily released upon adding a small tilt. Surfaces with very regular surface pattern, such as closely spaced micro‐trenches, can exhibit the so‐called High Hysteresis Suspended State (HySS). In this state the drops assume a spherical shape with air trapped below them, a characteristic feature of the Cassie–Baxter state, but show a very high contact angle hysteresis (up to >70°), typical for the Wenzel regime. The HySS regime is studied as a function of the surface geometry, applied pressure and the mass of the drop. Through roll‐off measurements it is shown that surfaces with controlled trapping conditions can be generated, where drops can be captured, however, upon addition of a small amount of energy (e.g., induced by tilt) can be released. The parameters that can be used to control the “depth” of the trap are elucidated.
One‐Step Spraying Fabrication of Superomniphobic Coatings with Anti‐Flame, Anti‐Corrosive, and Mechanochemically Durable Ability
Authors: Bu Xinyu , Zhang Hailong , Sun Chaofan , Ji Xingxiang , Tao Furong , Gai Ligang , Jiang Haihui , Liu Libin
Published: September 2022

A durable and high‐quality superomniphobic coating that gives good repellency to water and organic liquid with lower surface tension is critical for basic research and practical applications. Although it has made significant progress, incorporating flame retardancy without sacrificing its superomniphobicity and durability remains a challenge. Here, these challenges are addressed by one‐step spraying suspension consisting of epoxy resin, micro/nano‐particles, and flame retardant. The durability and flame retardancy can be regulated by adjusting the mass ratio of different components and curing temperature. The resulting coating possesses good superomniphobicity (repelling liquids with surface tension as low as 21 mN m−1) and mechanochemical durability even under severe environments such as harsh abrasion, high temperature, erosion of aqua regia, and other strong alkaline substances. In addition, the coating is resistant to metal corrosion and exhibits excellent flame retardance ability. Combined with this convenient spraying process, the coating is more conducive to realizing industrial production.
Responsive Chiral Photonic Cellulose Nanocrystal Materials
Authors: Qu Dan , Rojas Orlando J. , Wei Bing , Zussman Eyal
Published: September 2022

Responsive photonic crystals have attracted significant attention in fundamental scientific research and technological applications. Upon applying external stimuli, such as mechanical, electrical, magnetic, and optical triggers, the optical properties of photonic crystals can be actively tuned. Among a large number of photonic crystals, cellulose nanocrystals (CNCs) are considered one of the most promising materials due to their renewability, simplicity of preparation, and unprecedented chirality. A comprehensive overview of the fundamental design principles, methodologies, responsive mechanisms, and practical applications of responsive chiral photonic CNC materials is presented here. The changes in helix pitch, refractive index, orientation, and resulting structural and optical properties of chiral photonic CNCs in response to various stimuli are discussed. Thereafter, novel applications of responsive chiral photonic CNCs, such as colorimetric sensors, photonic actuators, rewritable photonic papers, and anti‐counterfeiting smart tags are described. We conclude by discussing future challenges and opportunities for developing high‐performance responsive chiral photonic CNC materials.