bluuebunny/crossref_metadata_2025 huggingface dataset:
Millî Mücadele’den Cumhuriyet Dönemine İngiliz Belgelerinde Suriye ve Mısır’daki “Kemalist Ajanlar”
Authors: MÜJDECİ Mustafa
Published: June 2022

Bu çalışmada 1921-1926 yılları arasını kapsayan dönemde Ortadoğu’da görev yapmış bazı Türk görevlileri ve faaliyetleri İngiliz belgeleri zaviyesinden incelenecektir. “Turkish and Kemalist Agents” başlığını taşıyan dosyada yer alan belgelerde özellikle bölgede görev yapan Türk görevliler konu edilmiştir. Kahire merkezli İngiliz Yüksek Komiserliği’nin kaşesini taşıyan bu belgeler Şam, Halep, Beyrut ve Kahire gibi merkezlerdeki İngiliz görevliler tarafından hazırlanmış gizli ibareli raporlardan müteşekkildir. Çalışmada resmi kayıtların ortaya konulması ve değerlendirilmesi yapılacak olsa da istihbarat ve ajanlıkla ilgili faaliyetlerin doğası gereği “bilinmeyen/açıklanamayan” ve “kapalı” kalan kısımlarının olduğu göz önünde bulundurulmalıdır.
I dialog. Intersektionella läsningar av hemhörighet, migration och kunskapsproduktion
Authors: Lundberg Anna , Farahani Fataneh
Published: June 2022

The dialogue-based article departs from our persistent research engagement with intersectional feminist approaches and questions related to racialisation, representation, locationality and positionality. We focus on the notion of home and homelessness, longing and belonging, migration and knowledge production. Some of the troubling questions we engage with are: How are the (im)possibility of feeling at home, migratory subject positions, and knowledge production conditioned by shifting socio-political contexts, culturally coded circumstances and the conceptualisation of difference? How do constantly shifting and intersected power hierarchies (re)shape the conceptualisation and (re)presentation of the certain types of knowledge and knowledge-makers through academic production, and through literary and visual means? These questions are discussed in dialogue between us, two Swedish gender researchers interested in cultural practices and cultural representations. The article unfolds through a dialogical method where, initially, our respective positions and research inputs, in relation to the article’s questions, are presented. The article continues to discuss the very same questions predominantly through different literary and visual examples. Chimamanda Ngozi Adichies’ TED talk, “The Danger of a Single Story”, has an evolving and central role in our dialogue. By linking different examples to the existing intersecting institutionalised power relations, we show that the personal is institutional.
Rasifiering av kunskapsproduktion
Authors: Farahani Fataneh , Thapar-Björkert Suruchi
Published: June 2022

The central aim of this article is to examine intersectional processes of racialisation within the academic communities: racialisation of knowledge producers and their produced knowledge. We explore what kinds of knowledge productions and knowing subject positions are rendered (im)possible in everyday academic interactions. We use our racialised scholarly experiences as a methodological entry point to contextualise the navigations and negotiations of shifting and intersecting power relations. Our analytical reasoning is presented through several steps. First, we discuss how academic habitus and affiliations maintained in various formal and informal forums are based on established, racialised norms. Second, we discuss how the presence or absence of epistemic entitlement within different academic settings and communities is established through racialised hierarchies. Thus the physical, social, intellectual and emotional spaces that we inhabit create comfort zones for some and discomfort zones for others. Third, we argue how managing the existing accent ceiling becomes a mode for navigating the conditioning norms of whiteness. In our conclusions, we reflect on the passivity, silences as well as (mis)use of the vocabulary of anti-racism and intersectionality as a form of ‘white’ capital for shoring their privileges further rather than undoing it.
Retrofili och begäret efter det förflutna
Authors: Fjelkestam Kristina
Published: June 2022

In this article, I question hierarchies of temporality by a critical examination of difference, that is, the time conception of a still indicative demarcation between past, present and future characteristic of the historical consciousness in Western society. My approach consists of a tripartite theoretical argument, which makes up for the first part of the article. The first step is constituted by my thesis in which I claim that a pivotal driving force in Western hierarchical historiography consists of the desire for the past, implicating a desire for difference. The second step complicates this desire by establishing a multidimensional model of desire, in which difference is diffused into differences motivated by cognition, emotion, politics and sexuality. The third step raises the possibility of dissolving difference altogether by an analytical concept I name retrophilia, love of the past, where time levels are claimed to be encouraged to collapse. In the second part of the article I concretize my argumentation by a reading of Gabriella Håkansson’s historical novel Aldermanns arvinge (Aldermann’s heir, 2013), set in the eighteenth century. By using a multidimensional model of desire and the figuration of retrophilia as reading tools, I conclude that the novel stages difference in the plural rather than the singular. These differences are evoked by multidimensional desires in which the past does not have to play the part of the Other. Instead embodiment and sensual experience give way to alternative ways of understanding both time and history.
Educational tourism and its challenges during the pandemic
Authors:   Grigol Robakidze University, Gvaramadze Anna
Published: June 2022

Educational tourism, also known as edu-tourism, is one of the trends that have higher growth in recent years. The aim of the article is to highlight the importance of the educational tourism and the impact of COVID 19 on educational tourists. This is a theoretical research based on the review of appropriate literature, usage of secondary sources, logical construction and the scientific induction. Nowadays, tourists are beginning to give more importance to new ways of knowing different tourist destinations, so the possibilities of learning grow significantly. Educational tourism delineates its boundaries with other types of tourism and education activities. It is one of the famous sub-types of tourism in the world today. Its popularity and necessity in the tourism market increases day by day. To define simply, educational tourism is when the main purpose of the trip is the learning itself. Educational tourism is considered as an essential market segment in the tourism industry and not surprisingly, many countries use it as one of the main earning source. The research revealed that even though definitions of educational tourism and tourists vary, there is still the way to conceptualize the market segment and look at the broad range of activities, such as: school trips, study tours, exchange programs, under and post graduate studies, short courses, language courses and other classic educationrelated activities. It was also found that despite the pandemic compared to other countries, the number of educational tourists leaving Georgia is higher than in previous years.
Realization of Child Rights in Municipalities
Authors:   Grigol Robakidze University, Kiladze Sopio
Published: June 2022

The Code on the Rights of the Child is the legislative act of utmost importance, which created legal bases for realization of the UN Convention on the Rights of the Child. Amongst other important novelties, it defines delegation of certain functions regarding child protection on municipalities, which changes attitude of Georgian state conceptually with regard to child protection. Taking into consideration, that according to Georgian Constitution, local issues should be decided at the local level and municipalities in comparison with other entities are closer to children and their families, these changes have huge positive impact, not only for ensuring child protection quality, but also for strengthening local self-governments in general. The Code on the Rights of the Child has defined municipality as the state entity in horizontal division of powers, under coordination of which are unified with child rights realization connected all state agencies, as well as public private entities implementing public functions. Also, municipalities have possibility to implement their own rights in child rights field, but at the same time, obligation to fulfill delegated rights from concrete state entities. The Code defines concrete mechanisms, which have huge importance, on the one side, for strengthening weak developed self-governments, on the other side, for ensuring child rights.
Mencari Indonesia 3: Esai-Esai Masa Pandemi
Authors: Tirtosudarmo Riwanto
Published: June 2022

Buku ini adalah edisi revisi dari seri ketiga Mencari Indonesia yang sebelumnya telah diterbitkan pada 2019. Edisi revisi ini diterbitkan melalui program akuisisi Penerbit BRIN agar menjangkau khalayak pembaca yang lebih luas. Sebagaimana tecermin dalam judulnya, seri ketiga ini berisi esai-esai yang ditulis pada masa pandemi Covid-19, yang tidak hanya merupakan isu kesehatan belaka, tetapi juga memengaruhi tatanan sosial, ekonomi dan politik. Komentar-komentar penulis sebagai cendekiawan sosial yang menaruh perhatian khusus pada migrasi penduduk, dituangkan dalam bentuk tulisan-tulisan mengenai pelbagai isu sosial yang muncul saat pandemi, yaitu isu Papua, hantu komunisme, rekayasa sosial, kebebasan akademis dan isu-isu lain yang menjadi keprihatinan kita bersama. Buku ini, yang ditulis berdasarkan perspektif seorang intelektual dalam menghadapi berbagai persoalan bangsa yang kian kompleks saat pandemi, diharapkan dapat menjadi literatur tidak hanya kalangan peneliti, akademisi dan kalangan yang menaruh minat khusus pada isu sosial dan politik bangsa, tetapi juga menjadi bacaan yang menginspirasi masyarakat umum
Cinematheraphy dalam Islam
Authors: Azharmubarak Muh
Published: June 2022

Cinematherapy is one of various techniques in therapy, but in this paper the researcher tries to combine cinematherapy techniques and the use of Islamic films in cinematherapy techniques. This study has a purpose, namely, to analyze the development of cinematherapy to help clients, and the lack of specific references that discuss cinematherapy in a religious context. Therefore, this research is here to try to contribute in the academic and social sciences in terms of counseling guidance so that it can contribute to the development of cinematherapy in Islam. The method used in this research is library research from the findings of journals that specifically discuss cinematherapy problems, namely 16 journals obtained through geoogle schoolar, garuda journals, sinta journals, and various searches found. The results of the study found that the cinematherapy technique has a high success rate in terms of general scientific fields but specifically the use of cinematherapy in Islam to overcome client problems has not been found. Therefore, researchers are trying to present Islamic values ​​in cinematherapy techniques as a form of scientific development in the form of cinematherapy as techniques and methods in overcoming client problems
Keywords: therapy, film, cinematherapy, islam
Problematika Guru Pai sebagai Konselor dalam Rangka Optimalisasi Layanan BK Di Sekolah
Authors: . Adiansyah
Published: June 2022

Education is expected to be a good community personality forming agent and full of responsibility through the role of BK teachers. In the process of implementation, education is faced with the complexity of problems, one of which is related to the lack of availability of BK teachers. So that this kind of condition forces in many schools / madrasahs still make PAI teachers as BK teachers and will eventually cause problems. This research is a library research in digging and getting an overview of the problems of PAI teachers as counselors in order to optimize BK services in schools. The problems experienced come from internal and external factors. Internal problems include perception and understanding considering that BK services are not the work of PAI teachers, BK services are considered as additional tasks, the lack of knowledge of PAI teachers in mastering the field of BK science. External problems include the lack of understanding of parents towards BK services, BK Services are only complementary as if it can be done by anyone, BK teachers are considered school police so that learners feel afraid of BK teachers.
Keywords: Problematics;Islamic Religious Education Teacher; Counselors
Keterampilan Konselor Berbasis Budaya
Authors: Roza Nidya , . Silvianetri , Fitriani Wahidah
Published: June 2022

The skills that must be possessed by a counselor are not only basic skills in understanding techniques to carry out various counseling services. However, a great counselor must also master and know the various values ​​that live in society, even though these values ​​are different from the values ​​they hold. It is possible that a counselor will deal with clients from different cultural backgrounds. This article was written with the aim of describing the cultural-based counseling skills that should be held by a counselor, especially counselors who are in a culturally diverse society. This article uses library research methods and literature studies by analyzing various interesting studies that give rise to new theories that can be seen logically to become something that can be applied in the field. Improving the skills of the counselor does not need to be by eliminating or removing the basic skills that the counselor already has. Even the various abilities that counselors already have can be used by utilizing and devoting these strengths to the fullest.
Keywords: counselor skills; culture-based counseling
Makna Feminin dalam Iklan Shampo Pantene Gold Series
Authors: Eko Saputro Deviq , Supriatno Djoko
Published: June 2022

Perempuan merupakan sosok yang berpengaruh dalam dunia periklanan, keterlibatan perempuan dalam dunia iklan didasari atas dua faktor, yaitu yang pertama perempuan adalah pasar besar dalam industri periklanan, kedua perempuan dipercaya mampu menguatkan pesan dalam iklan. Salah satu produk yang melibatkan perempuan dalam iklan yaitu produk shampo pantene gold series, Dalam iklan tersebut banyak banyak menggambarkan sisi feminin dalam diri perempuan seperti halnya senyuman, tubuh yang seksi. Tujuan dari penelitian ini adalah untuk mengetahui makna feminin dalam iklan shampo pantene gold series. Bahan dari penelitian ini berupa iklan shampo pantene gold series. Jenis penelitian ini adalah penelitian kualitatif dan bersifat deskriptif dengan metode analisis semiotika Roland Barthes yang mengkaji makna denotasi, konotasi dan mitos. Hasil dari penelitian ini ada 3 hal mengenai makna feminin dalam iklan. 1) makna feminin tentang keanggunan 2) makna feminin tentang kecantikan 3) makna feminin tentang keseksian.

 

Kata Kunci : Makna, Feminin, Iklan, Semiotika.
Analisis Perekrutan Caleg dari Partai Keadilan Sejahtera (PKS)
Authors: Navisatuzzuhro Luluk , Alkaff Alwi
Published: June 2022

Partai politik merupakan salah satu  tempat yang tepat untuk proses rekrutmen politik,dalam rangka mengorganisir kekuasaan secara demokratis. Dalam literatur-literatur ilmu politik di jelaskan bahwa partai politik memiliki beberapa fungsi seperti: Sarana Politik,Sarana sosialisasi dan pendidikan politik,Sarana rekrutmen politik,Sarana peredam dan pengatur konflik. Rekrutmen politik merupakan sebuah proses awal yang akan sangat menentukan kinerja perlemen (legislatif). Fokus masalah yang diteliti dalam skripsi ini adalah bagaimanaPerekrutan Caleg dari Partai Keadilan Sejahtera. DPD Kabupaten Jember. Tujuan penelitian ini adalah untuk mengetahui Bagaimana Perekrutan Caleg dari Partai Keadilan Sejahtera. DPD kabupaten Jember. Untuk mengidentifikasi permasalah tersebut maka jenis penelitian yang digunakan adalah penelitian kualitatif dengan pendekatan deskriptif. Adapun teknik pengumpulan data melalui, wawancara, observasi,dan dokumentasi.

Dari Penelitian ini memperoleh hasil yang dapat di tunjukan bahwa Analisis Perekrutan Calon Legislatif dari Partai Keadilan Sejahtera DPD Jember  menggunakan item 1). Mekanisme Rekrutmen calon Legislatif DPD  PKS Jember 2). Syarat-syarat dalam Proses Perekrutan Caleg 3).Macam-macam Kalangan dalam Perekrutan Caleg 4). Proses Pendaftaran Caleg 5). Pihak-pihak yang berwenang dalam perekrutan caleg 6). Proses penetapan Caleg  7).Faktor pendukung dan penghambat dalam perekrutan caleg 8). Jangka waktu dalam Perekrutan caleg  9). Biaya pengeluaran Caleg 10). Perolehan Kursi di parlemen dalam pemilu 2019 .

Adapun kesimpulan dari penelitian ini menunjukkan bahwa dalam tahap rekrutmen calon  anggota Legislatif melalui partai politik pada pemilu 2019 di partai PKS dilakukan oleh tim pemenangan pemilu yang di sebut Tim Penjaringan.Tim penjaringan merekrut kader dengan dua sumber yaitu Eksternal dan Internal. Sumber eksternal berasal dari masyarakat yang bukan kader partai sedangkan sumber Internal merupakan kader dari partai PKS sendiri.

 

Kata Kunci:Partai Politik, Rekrutmen Politik,Partai Keadilan Sejahtera (PKS)
Oral squamous cell carcinoma – clinical characteristics, treatment, and outcomes in a single institution retrospective cohort study
Authors: Janiak-Kiszka Joanna , Nowaczewska Magdalena , Kaźmierczak Wojciech
Published: June 2022

Introduction: Squamous cell carcinoma (SCC) is a common malignancy with high morbidity and mortality.

 Aim: The aim of this study was to analyze the data of patients treated for malignant tumours of the oral cavity at the Department of Otolaryngology, Head and Neck Surgery, and Laryngological Oncology Ludwik Rydygier Collegium Medicum in Bydgoszcz between 2003–2011 to asses the influence of risk factors on survival in patients with squamous cell carcinoma of the oral cavity.

  Material and methods: Material was collected from 62 patients treated for oral SCC between 2003–2011. Forty-three were men (69.35%) with a mean age of 56.33 years. The medical records were analysed, especially history, operative reports, histopathology reports, survival, adjuvant treatment and recurrence.

 Results: All patients underwent surgical treatment (33.87% also had partial removal of the lower jaw, 67.74% adjuvant radio-therapy, 11.29% radiochemotherapy). More than half reported to the doctor within 6 to 15 weeks from the onset of symptoms. The majority smoked and drank alcohol (96.32%). Five-year disease specific survival (DSS) was 68.69%.

 Conclusions: The age over 65 did not significantly influence DSS. The location on the anterior two thirds of the tongue gave the best outcome, while the worst outcome was observed in the retromandibular triangle area which was statistically almost significant (p = 0.06843). In the case of higher degrees of local and regional advancement and a higher stadium, a worse out-come was recorded. Positive surgical margins were identified in 11.29% of the cases, but they had no impact on the results of treatment. No worsening of the outcome was proven for the patients who reported to the doctor later than 15 weeks following the occurrence of symptoms.
Outcomes of surgery for gouty tophi in the extremities
Authors: Żyluk Andrzej , Fliciński Filip
Published: June 2022

 Introduction: Gouty tophi occur in approx. 50–60% of patients suffering from gout. Their occurrence is related to severity of disease and effectiveness of treatment. They develop more frequently in patients with long lasting and poorly controlled disease.

 Aim: The aim of the study was to evaluate the results of surgical treatment of gouty tophi of the upper and lower extremities.

 Materials and methods: The results of surgical treatment of gouty tophi in the extremities in 14 patients, 13 men and 1 woman, at a mean age of 51 years, are presented. Twelve patients had tophi localized in the upper extremities, whereas 3 had tophi in the lower limbs (1 patient had upper and lower extremity involved). The duration of disease to the operation was a mean of 8 years.

 Results: Seven patients received excision of a single tophus, and the remaining patients had 3–15 operations performed due to multiple tophi over a period from 3 months to 2 years. The treatment outcomes were assessed at a mean of 3 years (range 2–8) after the last operation in a form of phone interview.

 Conclusions: All patients declared satisfaction from the result of treatment. No case of complication or tumor recurrence was noted. The results confirm usefulness of surgical treatment in this form of gout.
Bite wounds to the hand – a review
Authors: Żyluk Andrzej
Published: June 2022

Bite wounds occur as a result of bite by an animal or a human. They are relatively frequent due to the growing number of pets living with people, as well as from inadequate human-animal interactions. The knowledge of most surgeons about the management of these injuries is relatively outdated, whereas the current literature points to important changes in this field. The article presents several aspects concerning epidemiology, classification, bacteriology, and characteristics of bite wounds to the hand. Based on the actual literature, detailed rules for the management of these injuries are described. This information may prove useful in the daily practice of surgeons and doctors at emergency departments who are frequently faced with bite wounds.
Comparison of the results of using a self-adhesive mesh and a polypropylene mesh in open inguinal hernia repair: a prospective randomized controlled study
Authors: Emral Ahmet Cihangir , Anadol Ahmet Ziya , Kozan Ramazan , Cetinkaya Gokay , Altiner Saygin , Aytac Abdulkadir Bulent
Published: June 2022

 Introduction: Inguinal hernia repair is the most common operation worldwide. The essential factors in hernia repair have been the postoperative quality of life, early return to work, low recurrence rate, and chronic pain prevention.

 Aim: The aim of this study was to compare the short- and long-term results of the self-adhesive mesh and the conventional polypropylene mesh in Lichtenstein repair.

  Material and methods: A total of 100 male patients were randomized and operated on, 50 with the self-adhesive mesh (S group), 50 with the conventional polypropylene mesh (P group). Prospectively, the patients were followed for an average of 36 months. The two groups were compared for the duration of surgery, duration of hospital stay, duration of daily activity/resumption of work, postoperative pain, chronic pain, recurrence, wound infection, hematoma/seroma formation, and postoperative analgesic consumption.

 Results: The study involved 39 patients in the P group and 37 patients in the S group who underwent inguinal hernia surgery. The P group had a longer mean operation time than the S group, and the difference between the two groups was statistically significant (45.1 ± 6.6 min vs. 28.8 ± 3.0 min, P = 0.0001). In recurrence, postoperative discomfort, chronic pain, length of hospital stay, daily activity/return to work, wound infection, hematoma/seroma, and postoperative analgesic use, there was no statistically significant difference between the two groups.

 Conclusion: It was found that the self-adhesive mesh did not produce statistically significant advantages over the conventional polypropylene mesh, except for operative time, in the Lichtenstein repair.
“Impact of preoperative gastrointestinal microbiota on weight-loss after Roux-en-Y gastric bypass: a pilot study “
Authors: Stefura Tomasz , Zając Maciej , Zapała Barbara , Gosiewski Tomasz , Skomarovska Oksana , Pędziwiatr Michał , Major Piotr
Published: June 2022

Background information: In recent years the composition of gut microbiome has been linked to development of several diseases. The goal of the following study was to establish whether it is connected to the outcome of bariatric surgery. The objective was to analyze the oral and gut microbiota of patients suffering from morbid obesity who underwent laparoscopic Roux-en-Y gastric bypass (LRYGB).

Methods: The following is a prospective cohort study that was conducted between November 2018 and June 2019. Participants underwent LRYGB surgery. Patients then were assigned to group 1- success (surgical participants who achieved a percentage of excess weight loss [%EWL] >50%), group 2 (surgical participants who achieved a %EWL <50%). The follow up to establish the %EWL was conducted 6 months after the surgery. Before surgery, oral swabs were obtained, and stool samples were provided. The endpoint was the composition of the gut microbiota.

Results: Group 1 consisted of 4 participants; group 2 consisted of 2 participants. No participants were lost to follow-up during the study. Participants in group 1 had an oral microbiota that was enriched in the family Tissirelia of the phylum firmicutes. Gut microbiome of patients in group 1 was enriched with with Tanerella of the Bacteroidetes phylum. Group 2 did not present enriched microbiota by any of the analyzed organisms. Gut microbiota was enriched by deltaprotebacteria class (phylum Proteobacteria), bernesiellaceae of the phylum Bacteroidetes.
Randomised controlled trial: standard lightweight mesh vs self-gripping mesh in Lichtenstein procedure
Authors: Zamkowski Mateusz , Ropel Jerzy , Makarewicz Wojciech
Published: June 2022

 Introduction: Lichtenstein hernioplasty has been a gold standard of hernioplasty for 30 years now. However, the procedure may be followed by an unacceptably high rate of chronic pain, numbness and discomfort.

 Aim: To compare outcomes of Lichtenstein repair using a Parietene ProGrip self-fixing mesh versus the standard lightweight macroporous mesh.

 Material and methods: As many as 141 patients with unilateral primary inguinal hernia participated in this single-centre, randomised, prospective, single-blind (patient-blinded) study. Randomisation yielded two treatment groups: control group of 88 patients treated with Lichtenstein method using lightweight standard mesh (LS) and study group of 53 patients receiving treatment with self-fixing mesh (PG). Patients were followed up for 6 months. Primary outcome was the presence and severity of postoperative pain at discharge, at 30 days and 6 months post-procedure. Other study parameters were: duration of the procedure, duration of hospitalisation, presence of early and late complications, time needed to return to full activity and patient satisfaction.

 Results: No statistically significant differences in pain severity were demonstrated at discharge or at long-term follow-up. In the first 30 days post-procedure the patients in the PG group complained of pain of greater severity on the NRS (2.0 vs 1.4) (P = 0.0466). The duration of the procedure in the PG group was 9.4 minutes shorter than in the LS group (P = 0.0027). No statistically significant differences between the groups were found in other studied parameters.

Conclusions: Self-fixing mesh can be safely used in inguinal canal repair procedures. It significantly shortened the duration of the procedure but at the same time did not reduce the severity of pain, including the rate of chronic postoperative inguinal pain.
Small-molecule inhibitors of the PERK-mediated Unfolded Protein Response signaling pathway in targeted therapy for colorectal cancer
Authors: Rozpedek-Kaminska Wioletta , Piotrzkowska Danuta , Galita Grzegorz , Pytel Dariusz , Kucharska Ewa , Dziki Łukasz , Dziki Adam , Majsterek Ireneusz
Published: June 2022

 Introduction: The newest data has reported that endoplasmic reticulum (ER) stress and PERK-dependent Unfolded Protein Response (UPR) signaling pathway may constitute a key factor in colorectal cancer (CRC) pathogenesis on the molecular level. Nowadays used anti-cancer treatment strategies are still insufficient, since patients suffer from various side effects that are directly evoked via therapeutic agents characterized by non-specific action in normal and cancer cells.

 Aim: Thereby, the main aim of the presented research was to analyze the effectiveness of the small-molecule PERK inhibitor NCI 12487 in an in vitro cellular model of CRC.

 Materials and methods: The study was performed on colorectal cancer HT-29 and normal human colon epithelial CCD 841 CoN cell lines. The cytotoxicity was measured by XTT assay, evaluation of apoptosis was performed by caspase-3 assay, whereas cell cycle analysis via the propidium iodide (PI) staining.

 Results: Results obtained have demonstrated that the investigated compound is selective only for HT-29 cancer cells, since at 25 μM concentration it significantly decreased HT-29 cells viability in a dose- and time-dependent manner, evoked increased caspase-3 activity and arrest in the G2/M phase of the cell cycle. Moreover, NCI 12487 compound markedly decreased HT-29 cells viability, increased caspase-3 activity and percentage of cells in sub-G0/G1, thus promoted apoptosis of cancer HT-29 cells with induced ER stress conditions.

 Conclusion: Thus, based on the results obtained in this study it may be concluded that small-molecule modulators of the PERK-dependent UPR signaling pathway may constitute an innovative, targeted treatment strategy against CRC.
Ileal pouch-anal anastomosis in paediatric age group: perioperative period, functional outcome and patient satisfaction
Authors: Sosnowska-Sienkiewicz Patrycja , Michalik Karolina , Mańkowski Przemysław
Published: June 2022

 Introduction:  Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is a procedure which enables reconstruction of the continuity of the gastrointestinal track after resection of the large intestine and rectum. The most common diseases that require this type of resection include: ulcerative colitis and familial adenomatous polyposis.

 Aim: The study aimed to determine the effectiveness of IPAA in the surgical treatment of the paediatric age group.

 Material and methods: The research material was collected based on medical records of 21 patients who underwent proctocolectomy at the Department of Pediatric Surgery, Traumatology, and Urology of the Medical University of Poznan in 2000–2021.

 Results:  In a group of 21 patients, 11 children were qualified for proctocolectomy due to ulcerative colitis (UC), 6 due to familial adenomatous polyposis (FAP), 3 due to Hirschsprung’s disease (HD), and one child due to Crohn’s disease (CD). Early complications in treated patients included dehiscence of the postoperative wound, bleeding from the lower gastrointestinal tract and anastomotic leakage. Late complications included pouchitis, stenosis of the ileostomy, narrowing of the anastomotic site and soiling. Quality of life was rated at an average of 9–10 by 16 patients on a scale of 1–10.

 Conclusions: IPAA is a proven method of reconstruction for the paediatric age group requiring proctocolectomy. Complications are common, most often related to the underlying disease and the clinical condition of the patients. Despite possible complications, patients rate their quality of life high on the scale. Each qualification for surgery should be carried out in a multidisciplinary team.
Skin Metastases of Gastrointestinal Neuroendocrine Tumors – Literature Review
Authors: Molasy Bartosz , Zemła Patryk , Kuśnierz Katarzyna
Published: June 2022

 Introduction: Gastrointestinal neuroendocrine neoplasms arise from cells of the diffuse endocrine system (DES) located in the digestive tract. They are often diagnosed in an advanced stage, when distant metastases appear. Skin metastases of neuroendocrine tumors are extremely rare.

 Aim: The aim of the study was to collect and analyze cases of skin metastases of gastrointestinal neuroendocrine neoplasms.

 Materials and methods: A literature search across PubMed and Medline databases from 1969 up to 2021 was performed. We reviewed English literature according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. The following keywords were used: “neuroendocrine tumor”, “neuroendocrine neoplasm”, “neuroendocrine carcinoma”, “NET”, “NEN”, “skin and cutaneous metastases”, “lymph nodes”. The characteristics of patients, grading, tumor localization and other data that was found in publications were assessed. Case reports and case series were included.

 Results: The initial search strategy yielded 14 results in PubMed and 3 in the Medline database. We removed duplicates after we imported the citations with a citation manager. We found 17 publications concerning skin metastases of neuroendocrine neoplasms. The analysis of 18 cases concerned 13 NECs and 5 NETs. In most cases, the metastases are small, painless and located on the scalp or lower extremities. Skin metastases may be the first symptom of the disease. The pancreas is the most common primary tumor site.

 Conclusions: NEN metastases to the skin are often diagnosed with disseminated neoplastic process, which is associated with poor prognosis and high mortality. NET metastases to the skin may occur with an unknown primary site. Skin metastases of neuroendocrine tumors should be considered during the diagnosis of skin tumors.
Does the orientation of the styloid process cause Eagle Syndrome? An anatomical study of the styloid process in 72 Greek skulls
Authors: Paraskevas George , Poutoglidis Alexandros , Lazaridis Nikolaos , Asouhidou Irene , Chrysanthou Chrysanthos , Apostolidou Elpida , Iliou Kalliopi , Tsetsos Nikolaos , Forozidou Evropi , Karamitsou Paraskevi , Skalias Antonios , Vlachtsis Konstantinos
Published: June 2022

Introduction: Patients often suffer from an elongated styloid process. This clinical entity is well known and is described as Eagle syndrome. The presence of this anatomical variation is not always associated with symptoms. However, there is a strong correlation between the elongated styloid process and Eagle syndrome

 Aim: This study aims to calculate the incidence of elongated styloid processes in the Greek population, to analyze the morphometric characteristics of styloid processes, and to compare these among sexes.

 Material and methods: This is a single-center retrospective study. All skulls were donated to the Department of Anatomy, the Ari-stotle University of Thessaloniki from January 2013 to May 2019 for research purposes. A styloid process longer than 30 mm was considered elongated. We used Welch’s t-test for the statistical analysis of the data.

 Results: The prevalence of elongated styloid processes was 35%. The average diameter was 3.32 mm and the average total length was 25.02 mm. There was no statistically significant difference between male and female skulls, though the female styloid processes were slightly longer and the male ones were slightly wider. Symmetry was recorded in 31% of skulls. Average axial angle was 650 but in 4% of cases it was less than 200.

 Conclusions: The elongated styloid process is not a rare entity. Eagle syndrome should always be considered in the differential diagnosis when patients report chronic sore throat. Our anatomical findings add a new dimension to the etiopathogenesis of Eagle syndrome.
Selective Spinal Nerve Root Block as an efficacious modality of treatment in lower backache with radiculopathy in cases of single level prolapsed intervertebral disc
Authors:   Department of Orthopaedics, Bharati Vidyapeeth Medical College and Hospital, Katraj, Pune, Khurana Vipul , Pundkare Gopal ,   Department of Orthopaedics, Bharati Vidyapeeth Medical College and Hospital, Katraj, Pune
Published: June 2022

Background: Back pain affects everybody at some point in their life and is one of the most common complaints evaluated by a spine surgeon. Lower limb radiculopathy is commonly associated with conditions like disc herniation, facet or ligamentous hypertrophy, and spondylolisthesis. The present study was conducted to assess the prognosis after a single dose of Selective Spinal Nerve Root Block in patients with lower backache with radiculopathy with a single level disc prolapse. Methods:Forty patients with complaints of lower backache with lower limb radiculopathy with a single level Prolapse Intervertebral disc[Magnetic Resonance Imaging (MRI) diagnosed] were assessed on the basis of Visual Analogue Scale score and Roland Morris Questionnaire score at different time intervals pre and post single level spinal nerve root block to assess the reduction in pain. Results:Pain recurrence was noted in four (10%) patients at 3-month post block and total five patients at six months post block. Five (12.5%) patients underwent a surgical procedure after six months of a block. A significant (p<0.0001) reduction in the Roland Morris Questionnaire scores (Mean 19.53) and Visual Analogue Scale score for back pain (Mean 4.48) and leg pain (Mean 7.5) were observed during the follow-ups of Roland Morris Questionnaire scores at three months (Mean 2.55) and six months (Mean 3.55); with Visual Analogue Scale score at three months for back pain (Mean 1.60), leg pain (Mean 1.45) and six months for back pain (Mean 1.07) and leg pain (Mean 2.2) in 35 (87.5%) study subjects after block. Conclusion: The study recorded a pain-free period averaging six months with positive outcomes in almost all patients, indicating selective nerve root block efficacy among patients with lower back pain with radiculopathy with a single level prolapsed intervertebral disc, especially in younger patients and those with a short duration of symptoms.
STABILITY ANALYSIS OF ROCK SLOPE USING SLOPE STABILITY PROBABILITY CLASSIFICATION (SSPC) METHOD IN PIYUNGAN-PATUK AREA, YOGYAKARTA SPECIAL REGION
Authors: Wiratama Rana
Published: June 2022

Landslide events in an area are manifestations of unstable slope conditions so evaluation of slope stability and mapping of areas prone to landslides is very important as an effort to mitigate landslides. In this study, the Slope Stability Probability Classification (SSPC) method was used to evaluate slope stability in the Piyungan-Patuk area. which is a rock mass classification system for slope stability that classifies 3 (three) different rock masses through a three-step approach namely: Exposure Rock Mass (ERM), Reference Rock Mass (RRM), and Slope Rock Mass (SRM). Slope stability analysis results on 18 selected slopes obtained a probability of slope stability with very low to very high classification with a probability value of stability <0.5 to> 95, where the probability value is strongly influenced by rock mass parameters such as rock strength, discontinuity, and weathering rate.
ESTIMATION OF ANDESITE RESOURCES USING THE CROSS-SECTION METHOD OF PT. AKAM IN THE DISTRICT SORONG PROVINCE OF WEST PAPUA
Authors: Valderama Aldi F. , Hutapea Ricardo O.M.
Published: June 2022

One of the technical requirements in renewing mining operation permits, according to ‘Peraturan Menteri Energi dan Sumber Daya Mineral Nomor 34 Tahun 2017’, is the balance sheet of resources and reserves. Before the expiration of the production permit of PT. AKAM was then needed to calculate the andesite resource in the operation area of PT. AKAM in Sorong, Papua Barat. The Cross Section method is considered to be the best way to estimate the andesite resource because this method can be utilized to find out the layout of the overburden and mineral. The results highlighted that andesite resource in the operation area of PT. AKAM was approximately 405.780.313 m³, with a cover layer of 498,937 m³. The productivity age of PT. AKAM is predicted to be 49,64 years, with an annual production of 8.112 m³
MINERALS AND COAL RESERVES POTENTIAL IN INDONESIA AND THE WORLD
Authors: Setiawan Arif
Published: June 2022

Mineral and coal resources and reserves in the world even in Indonesia need to be known, considering that until now more and more industries need it, so that it can cause a reduction in raw material supply for the industry. To find out the number of resources and reserves, data or information is needed, so after knowing the relevant information, it is expected to know what strategies to do. The method used is the comparison between Indonesian data and world data so that the percentage of ownership in Indonesia can be known. The results showed that coal in Indonesia was estimated to range from 2% -3% of coal in the world. For metal minerals, Indonesia had 6.08% nickel, 6.82% cobalt, 14.05 lead, 9.63% zinc, 3.33% bauxite, 0.72 iron, 4.63 gold, 16.67% tin, 3.29% copper, 19.17 manganese, 0.44% chromium, 0.17 titanium.
CULTURAL PUBLIC INSIGHTS ON PT. SDIC PAPUA CEMENT INDONESIA LIMESTONE MINING AT MANOKWARI
Authors: Awandoi Maria A. I. , Birawaputra Indra
Published: June 2022

People in the Doput village and Misapmeysi villages, based on their local knowledge and understandings, have different points of view in perceiving problems resulting from mining activities, particularly impacts that have been experienced. To find out the villagers’ perceptions, a questionnaire consisting of questions about language, local knowledge, technology, art, traditional livelihood, religion, and kinship was distributed to 50 respondents in the two villages. The results showed that 74%– 88% of the respondents have good perceptions in terms of local culture. This is because the respondents assumed that the local culture still existed, and even would be preserved both before and after the limestone mining activities of PT. SDIC Papua Cement Indonesia Manokwari. The average percentage of cultural variables were perceived from good to very good; language (74%), natural knowledge (88%), technology (83%), art (74,67%), living livelihood traditional (83,33%), religion (85%), and kinship (84%). In general, the results indicated that the limestone mining in Maruni has been positively perceived by the villagers, especially from the cultural perspective.
The Presence of Trihalomethanes and Haloacetic Acids in Tropical Peat Water
Authors: Zevi Yuniati , Qadafi Muammar , Notodarmojo Suprihanto
Published: June 2022

The presence of dissolved organic matter (DOM) in tropical peat water affects the appearance of trihalomethanes (THMs) and haloacetic acids (HAAs) in natural water sources. However, information about the presence of THM and HAA in tropical peat water is still limited. This study was conducted to determine the presence of THMs and HAAs in tropical peat water taken from a canal and a river in Riau Peatland, Indonesia, influenced by the seasons and the tides. DOM was measured by dissolved organic carbon (DOC) and UV254 absorbance. The presence of THMs and HAAs was determined based on total THM4 and HAA5 and correlated with chloride and bromide concentrations. The concentrations of chloride and bromide in the river water were higher than in the canal water because of tidal influence. Total THM4 in canal water reached 22.70 ± 0.90 and 10.78 ± 0.71 µg/L in the dry and rainy seasons, respectively, but only reached 16.64 ± 1.93 and 5.52 ± 0.05 µg/L in the river water. In contrast to THM4, total HAA5 in the river water was higher than in the canal water and reached 104.01 ± 4.67 and 106.39 ± 9.53 µg/L in the dry and rainy seasons, respectively, but only reached 9.83 ± 0.48 and 56.87 ± 6.11 µg/L in the river water. THM4 predominated in the dry season while HAA5 predominated in the rainy season.
Tình trạng thiếu năng lượng trường diễn và một số yếu tố liên quan ở phụ nữ tuổi sinh đẻ tại Vũ Thư, Thái Bình năm 2015.
Authors: Trần Việt Nga , Lê Danh Tuyên , Phạm Vân Thúy , Trần Thúy Nga , Ninh Thị Nhung
Published: June 2022

Thiếu năng lượng trường diễn gây nhiều hậu quả cho phụ nữ tuổi sinh đẻ như tăng nguy cơ mắc các bệnh nhiễm trùng và giảm khả năng đáp ứng miễn dịch dẫn đến chậm hồi phục khi mắc bệnh. Phương pháp: Nghiên cứu cắt ngang mô tả, chọn mẫu ngẫu nhiên hệ thống 548 phụ nữ tuổi sinh đẻ 20-49 tuổi tại huyện Vũ Thư tỉnh Thái Bình. Mục đích: Mô tả tình trạng thiếu năng lượng trường diễn và một số yếu tố liên quan. Kết quả: Trung bình chiều cao 152,7± 4,4 (cm), cân nặng 46,5 ± 5,3 (kg), BMI 19,9 ± 2,0 (kg/m2), Tỷ lệ thiếu năng lượng trường diễn là 20,4%, trong đó, độ I là 14,1%, độ II là 3,8% và độ III là 2,6%. Đối tượng có thu nhập thấp, có nhiều hơn hai con, bị tiêu chảy cấp trong tháng qua, hay bị thiếu máu có nguy cơ cao bị thiếu năng lượng trường diễn (p< 0,05). Cần tích cực triển khai các can thiệp dinh dưỡng, nhằm nâng cao thể trạng và sức khỏe cho nhóm phụ nữ tuổi sinh đẻ.
ĐẶC ĐIỂM KHẨU PHẦN CỦA LƯU HỌC SINH LÀO TRƯỜNG ĐẠI HỌC TÂY BẮC NĂM 2020
Authors: Phạm Thị Thanh Tú , Lê Đức Cường , Nguyễn Văn Công
Published: June 2022

Mục tiêu: Nghiên cứu mô tả đặc điểm khẩu phần ăn của lưu học sinh Lào trường Đại học Tây Bắc, mức độ đáp ứng nhu cầu khuyến nghị về hàm lượng các chất để đưa ra những khuyến nghị phù hợp. Phương pháp: Điều tra tần suất tiêu thụ lương thực, thực phẩm và khẩu phần ăn 24 giờ trên 82 đối tượng là lưu học sinh Lào. Kết quả: Nghiên cứu cho thấy năng lượng khẩu phần trung bình của lưu học sinh là 2007,1 ± 362,2 kcal/ngày, Tỷ lệ các chất sinh năng lượng trong khẩu phần của lưu học sinh Lào P:L:G là 15,8 : 32 : 52,1. Tỷ lệ lưu học sinh Lào đạt được nhu cầu khuyến nghị về năng lượng là 35,4%, trong đó tỷ lệ nam đạt nhu cầu khuyến nghị là 29,5% và nữ là 42,1%. Tỷ lệ lưu học sinh đạt nhu cầu khuyến nghị về phospho đạt tỷ lệ cao nhất 86,6%, tiếp theo là kẽm đạt 74,4%, vitamin A đạt 62,2%, vitamin C đạt 59,8%, vitamin B1 đạt 54,9%, Canxi đạt 30,5%, vitamin B2 đạt 25,6% và cuối cùng thấp nhất là sắt đạt 12,2%. Tỷ lệ các lưu học sinh nam đạt nhu cầu về chất khoáng và vitamin hầu hết cao hơn nữ.
MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN TCBP Ở TRẺ 7-11 TUỔI TẠI 2 TRƯỜNG THUỘC HUYỆN THUẬN CHÂU VÀ THÀNH PHỐ SƠN LA, TỈNH SƠN LA, NĂM 2020
Authors: Đào Thị Lan Hương , Phan Hướng Dương , Phan Ngọc Quang
Published: June 2022

Nghiên cứu cắt ngang nhằm xác định một số yếu tố liên quan đến TCBP (TCBP) ở học sinh tiểuhọc tại hai trường thuộc huyện Thuận Châu và thành phố Sơn La, tỉnh Sơn La. Tổng số 865 phụhuynh của trẻ ở độ tuổi 7-11 tại địa bàn được chọn tham gia nghiên cứu. Sử dụng bộ câu hỏi đã được thiết kế sẵn để thu thập các thông tin về: gia đình, chế độ ăn uống và hoạt động thể lực của trẻ thông qua phỏng vấn gián tiếp bố, mẹ hoặc người chăm sóc trẻ. Kết quả cho thấy trẻ nam, ở thành phố, dân tộc Kinh, gia đình có chi phí trung bình cho thực phẩm của cả gia đình > 4 triệu/ tháng, thói quen ham ăn/ăn nhiều, ăn > 3 bữa chính/ngày, ăn bữa cuối trong ngày lúc sau 20 giờ, xem ti vi
DIỄN BIẾN MỘT SỐ CHỈ SỐ NHÂN TRẮC VÀ ĐẶC ĐIỂM DẬY THÌ CỦA NỮ HỌC SINH DÂN TỘC THÁI LỨA TUỔI 15 TẠI BA TRƯỜNG THCS THUỘC HUYỆN THUẬN CHÂU, TỈNH SƠN LA GIAI ĐOẠN 2019 - 2021
Authors: Trần Thị Minh , Trần Khánh Thu , Nguyễn Thế Điệp
Published: June 2022

Mô tả cắt ngang kết hợp theo dõi theo chiều dọc được tiến hành trên 209 học sinh nữ dân tộcThái sinh năm 2006 ở 3 trường THCS tại huyện Thuận Châu tỉnh Sơn La nhằm đánh giá diễnbiến các chỉ số nhân trắc và đặc điểm tuổi dậy thì của trẻ. Sử dụng chỉ số Z-Score BMI theotuổi để đánh giá tình trạng dinh dưỡng. Kết quả cho thấy có 85,2% học sinh đã có kinh nguyệt,còn 14,8% chưa có. Thời điểm có kinh nguyệt phổ biến nhất là độ tuổi 13-14 tuổi với tỷ lệ66%; Mức tăng cân nặng và chiều cao khoảng 6,2 kg và 6,9 cm, tỷ lệ suy dinh dưỡng (SDD)thấp còi giảm mạnh từ 23,4% xuống 12,4% trong đó SDD thể nặng giảm từ 3,3% xuống 1,9%,thể vừa giảm từ 20,1% xuống 10,5%. Tỷ lệ SDD gầy còm giảm từ 2,4% xuống còn 0,5%. Tỷlệ thừa cân béo phì (TCBP) giảm từ 4,3% còn 1,0%.