bluuebunny/crossref_metadata_2025 huggingface dataset:
A changing landscape in collection development
Authors: Schmidt Jane , Jin Lei , Yan May
Published: August 2021

Ryerson University Library has been exploring different just-in-time acquisition models that provide us with cost-effective ways to purchase monograph titles with guaranteed usage. Based on our experience with Ebrary on the PDA (Patron Driven Acquisitions) Pilot, and with YBP on the DDA (Demand Driven Acquisitions) project, this discussion will focus on the theory behind our approach, the technicalities of implementation, and implications for future collection development strategies.
Perancangan Interior Omah Batik Di Bayat
Authors: Isma Annisa , Budiwiyanto Joko
Published: August 2021

Abstrak Perancangan Interior Omah Batik Di Bayat dengan tujuan menampung kegiatan - kegiatan  untuk mengembangkan batik tradisi khususnya di Bayat dengan menghadirkan tema dari beberapa motif pada batik  yang  di kemas dalam gaya artdeco Perancangan ini  menawarkan  fasilitas seperti galeri, toko,workshop,café da juga lobby. Tujuan tersebut dicapai dengan metode desain yang menggunakan proses desain meliputi input, sintesa dan output. Input berupa data literatur, lapangan, dan,sintesa melalui proses analisis desain, output berupa hasil desain. Pendekatan yang digunakan adalah pendekatan fungsi, ergonomi, tema dan gaya dan juga bahan. Analisa desain mengambil ide dari beberapa motif batik yaitu motif kawung, sidomukti, dan parang yang dipadukan dengan gaya artdeco. Hasil desain berupa perancangan Interior Omah Batik Di bayat yang mempunyai fasilitas utama berupa lobby, toko, galeri, café dan workshop.Fasilitas penunjang  yang meliputi penginapan,  ruang audio visual dan  perpustakaan yang di kemas dalam gaya artdeco.Kata Kunci: interior Oma Batik, motif batik, art deco
A Combination Design of Bag, Chair, Charger, Tables Made with Hazardous Waste Raw Materials in Tackling Environmental Pollution in the 4.0 Revolution Era
Authors: Fatah Muhamad Fadilah , Oftariano Melyndo Ari , Setiabudi Taksulanapurusa Zakly , Haryanto Eko Sri
Published: August 2021

The design of bags, chairs, chargers and tables is intended for commuter workers who carry out mobility activities every day. Design works that help to support commuter worker activities use a multi-functional system. The multi-function system is indicate by the shape and features attached. This product design method uses several stages including; 1) problem identification; 2) literature study: 3) design sketches, and: 4) design. The design results are turned into chairs, tables for lesehan (sitting on the floor) and bags. In addition, the other things are the storage box to store equipments for commuter workers while doing mobility and a solar cell which functions to capture sunlight which will be converted into electrical energy for energy sources to charge cellphones. Design works can be used in accordance with their respective functions. Design works carry the principle of multifunction, easy use, strong, lightweight and flexible. It is hoped that the design for this multi-functional products can be practical in use in the development of creative industries, and can overcome environmental pollution problems. From a theoretical perspective, it can be a reference for academics and science.
The Interior Designing of Lawu Resort Hotel with Tirta Intanpari Batik Theme in Tawangmangu
Authors: Widiyanto Wahyu Tri , Hapsari Putri Sekar
Published: August 2021

The increasing number of tourists visiting Tawangmangu tourist attraction, Central Java, and yet insufficient lodging facilities are some of what is behind the interior designing of Lawu Resort Hotel. Lawu Resort Hotel is a lodge with facilities to accommodate tourist activities. The design theme is intanpari tirta batik design with a contemporary style, meanwhile the design goal is to present an interior that follows current times advancement but still concerns on the culture. The design method adopted the stages of the Pamudji Suptandar design process with an outline of the process consisting of input, synthesis and output. The scope of work includes a lobby, restaurant, coffee lounge and guest room. The design results are in the form of a design proposal, which includes design concepts, work drawings, material schemes and animation.
Restoring what no longer exists: therapeutic and cultural issues regarding female genital mutilation/cutting
Authors: Coho Christie , Parra Sepúlveda Roxana
Published: August 2021

Female genital mutilation/cutting/circumcision (FGM/C) is a form of childhood sexual violence, typically perpetrated by females on females, which has been passed down the generations across cultures and communities around the world. While the explanations for this practice involve love, future security, and cultural pride, the resulting expression of these ideals is a physical-cum-sexual/psychological damaging of the genitalia and the self for the purpose of suppressing and dominating the female, particularly her sexuality.
Exploring this form of child abuse and sexual assault, this article will provide an overview of female genital mutilation. Varying purposes and functions of the practice are then outlined, from both cultures of origin and feminist perspectives. Psychological defences enabling the perpetuation of this harmful practice are explored. Potential versions of the therapeutic work are considered, which might involve resolving confusion, letting go of psychological defences, processing trauma and grief, reconfiguring attachment patterns, and/or re/connecting with one's body and sexuality. The journey is from victim to non-perpetrating, resilient survivor.
The experience of domestic violence survivors in the US family courts: gender bias in the court
Authors: Fischel-Wolovick Lisa
Published: August 2021

There is a significant body of research on gender bias against women in the family courts. During the Covid-19 pandemic, battered women's vulnerability to domestic violence increased on a global level as women experienced a significant increase in the severity of abuse. The problems of gender bias and the treatment of battered women and their children have a long history of human rights' abuses. In particular, battered mothers have been the focus of gender-biased theories of parental alienation, used as a defence against claims of abuse and child maltreatment, despite a lack of empirical validity and acceptance. Additionally, the family courts in the United States are closed to the public and as a result there is a lack of transparency and accountability. A large-scale national study revealed that many supporting mental health professionals who provide custody evaluations lack a formal graduate education in domestic violence and child maltreatment. Furthermore, legislative presumptions that favour joint legal custody in custody decisions and requirements of co-parenting, fail to take into consideration the long-term public health risks of such chronic traumatic exposure. Finally, this article will address needed systemic reforms that include increased transparency, longterm court-monitoring, and supporting mental health professionals with formal graduate education in trauma, child development, and abuse, to promote resilience in vulnerable families.
The perfect man
Authors: de Mari Massimo
Published: August 2021

In this article I will describe a ten-year psychotherapy treatment, with a frequency of four to five sessions per week in the first two years, and one session every fortnight for the following eight years in prison, with a man sentenced to twenty-three years for murdering his wife.
I will analyse the complex personality of a young multi-talented male doctor, pushed to the edge of a chasm by a transgenerational destiny for males to be "the best" in everything.
This unconscious need forced him to build up a hypertrophic self of "the perfect man" who, faced with the frustrations of life, broke down, revealing a very fragile and immature core.
The collapsing of the ego led him to a killing which was meant to "save", in a distorted way, his project of being "the perfect father", without realising that he was, instead, destroying not only his wife's life, but his children's and his own life too.
DETERMINING THE EFFECTIVENESS OF A CPD PROGRAMME FOR ENHANCING SCIENCE TEACHERS’ SELF-EFFICACY TOWARDS MOTIVATIONAL CONTEXT-BASED TEACHING
Authors: Valdmann Ana , Rannikmae Miia , Holbrook Jack
Published: August 2021

The aim of this research is to determine the effectiveness of an enacted professional development (CPD) programme to promote teacher’s self-efficacy with respect to implementing motivational, context-based science teaching, following an education through science (EtS), three-stage model approach. The CPD is designed, based on a constructivist, socio-cultural professional development model (CSPM) to meet professional needs of each teacher within a predetermined teaching-learning approach and enacted through suitable instructional methods linked to teacher as learner, teacher as teacher and teacher as reflective practitioner. The effectiveness of the CPD is identified by means of a carefully constructed and validated Teacher Needs Questionnaire (TNQ), plus follow-up teacher interviews. Findings suggest the outcomes of the CPD, both from pre-post use of the TNQ and the undertaking of interventions, using teaching-learning modules based on the CPD, are effective in raising teacher’s self-efficacy with respect to new interdisciplinary content knowledge, teaching approaches and classroom implementation, seen as being in line with curriculum expectations. Key words: constructivist socio-cultural professional development model (CSPM), self-efficacy, Teacher Needs Questionnaire (TNQ), 3-stage education through science (EtS) model.
THE RELATIONSHIP BETWEEN SECONDARY SCHOOL STUDENTS’ SELF-REGULATED LEARNING SKILLS AND CHEMISTRY ACHIEVEMENT
Authors: Şen Şenol
Published: August 2021

Self-regulated learning skills (such as goal setting, organizing environment and time, seeking help and self-evaluation) are critical for students to be able to successfully and meaningful learn abstract concepts such as reduction, oxidation and electrolysis. The purpose of this research was to examine the relationships between self-regulated learning skills and chemistry achievement in Turkish secondary school students. Therefore, a structural equation model was developed and tested to model the relationships among task value, control of learning beliefs, performance-approach goals, mastery-approach goals, self-efficacy for learning and performance, metacognitive learning strategies, time and study environment management, effort regulation, and achievement in electrochemistry. Data was collected from 481 secondary school students through administration of the Achievement Goal Questionnaire, the Motivated Strategies for Learning Questionnaire and the Electrochemistry Concept Test. The results showed that students’ task value, performance-approach goals, and time and study environment management significantly positively correlated with achievement. Path analysis demonstrated that metacognitive learning strategies, mastery-approach goals, and effort regulation were predictors of students’ time and study environment management. Moreover, effort regulation, metacognitive learning strategies, and mastery-approach goals were found to have indirect effects, which were mediated by time and study environment management.
Key words: chemistry achievement, direct and indirect effects, self-regulated learning skills, secondary school students, path model.
EMPOWERING STUDENTS’ METACOGNITIVE SKILLS THROUGH NEW TEACHING STRATEGY (GROUP INVESTIGATION INTEGRATED WITH THINK TALK WRITE) IN BIOLOGY CLASSROOM
Authors: Listiana Lina , Susilo Herawati , Suwono Hadi , Suarsini Endang
Published: August 2021

Metacognitive skills play an important role in various students’ cognitive activities. Metacognitive skills can make the students become self-regulated learners. Metacognitive skills in biology teaching can be empowered through the implementation of the appropriate teaching strategies. This research was a quasi-experimental research designed to compare the effect of Group Investigation (GI) strategy, Think Talk Write (TTW), Group Investigation integrated with Think Talk Write (GITTW), and conventional teaching strategy on the students’ metacognitive skills empowerment in biology teaching. Sample of this research were 162 students of the first year natural science class of senior high schools in Surabaya, Indonesia, academic year 2014/2015. The students’ metacognitive skills were measured using essay questions test, given at the beginning and at the end of the research. The results of the research showed that the implementation of teaching strategies had an effect to empower students' metacognitive skills. GITTW learning strategy had the biggest effect on the metacognitive skills empowerment. TTW learning strategy could improve students’ metacognitive skills higher than GI and conventional teaching strategy. This proves that GITTW is one of the teaching strategies that teachers should use to maximise the students’ metacognitive skills empowerment. Key words: biology teaching, teaching strategy, group investigation, metacognitive skills, think talk write
Efficacy of Polylactic-Co-Glycolic Acid Plate as a Graft Material in Septorhinoplasty
Authors: Kang Jae-Yoon , Kim Min-Su , Im Se Yeon , Park Soo Kyoung , Rha Ki-Sang , Kim Yong Min
Published: August 2021

Background and Objectives Polylactic-co-glycolic acid (PLGA) plate has been recognized for its biocompatibility and biomechanical properties and used widely in various clinical fields. The aim of this study was to evaluate the usefulness and reliability of PLGA plate as a graft material in septorhinoplasty.Subjects and Method Medical records were retrospectively analyzed for patients who underwent septorhinoplasty including extracorporeal septoplasty from January 2017 to June 2020. We evaluated demographics, diagnosis, operation techniques, and complications of PLGA plate as a graft material used in these patients.Results A total of 33 patients were enrolled in this study. Twenty-eight were male and 5 were female. The median age was 32 years old. The follow-up period after surgery was 6-32 months, and the mean follow-up period was 18.03 months. The PLGA plate was used in unilateral spreader graft (n=17), bilateral spreader graft (n=10), batten graft (n=3), strengthening of septal extension graft (n=2) and columellar strut graft (n=3), and fixing L-strut during extracorporeal septoplasty (n=12). During the follow-up period, no patient experienced extrusion or exposure of the grafts. Mild complications, such as redness of the columella skin, granulation in the marginal incision site, and pain on the nasal dorsum were observed in three patients; these complications were temporary and patients improved with conservative treatments.Conclusion The PLGA plate may be a useful graft material in correcting deviated nose especially when the harvested septal cartilage is insufficient and if used carefully in limited locations such as L-strut and columella.
Sublingual Gland Excision and Sclerotherapy for Plunging Ranula and Management of Recurrence
Authors: Kim Hyun Jung , Yi Hee Jun , Park Jin-A , Choi Nayeon
Published: August 2021

Background and Objectives For plunging ranula, excision of the sublingual gland has been the major treatment option, with sclerotherapy being widely used as minimal invasive treatment. We compared the outcomes of these two methods as an initial treatment for ranula and investigated the outcomes of salvage procedure in recurred patients.Subjects and Method Patients were classified into the excision group (n=35) and the sclerotherapy group (n=39) according to the type of their initial treatment. The outcomes of the initial and salvage treatment were determined as recurrence or non-recurrence at 3 months after treatment, and statistically compared between the excision and the sclerotherapy groups.Results Recurrence in the sclerothearpy group (n=20, 51.3%) showed a significantly higher rate (p<0.001) than in the excision group (n=3, 8.6%). Recurring patients who received treatment different from the initial treatment (n=7) were cured, while those who had same procedure as the initial treatment (n=11) showed recurrence of 72.7% (n=8). There was no procedure related complication among the patients.Conclusion Sublingual gland excision was more effective than ethanol sclerotherapy for the treatment of plunging ranula. In addition, sublingual gland excision was effective even after the failure of ethanol sclerotherapy.
Effect of Temporal Bone Fracture on the Prognosis of Benign Paroxysmal Positional Vertigo
Authors: Chang Munyoung , Lee Sei Young , Mun Seog-Kyun
Published: August 2021

Background and Objectives This study aimed to investigate whether benign paroxysmal positional vertigo (BPPV) accompanied by temporal bone fracture would be more resistant to canalith repositioning procedures (CRPs) than idiopathic BPPV.Subjects and Method Seventy-eight patients with BPPV were included in this study. Among them, 13 patients had temporal bone fractures and 65 had no temporal bone fractures. To identify the factors related to the number of CRPs performed until the remission of BPPV, sex, age, the presence of temporal bone fracture, hypertension, diabetes, dyslipidemia or osteopenia, BPPV affected side, and the type of affected semicircular canal were analyzed using the univariable regression analysis. Thereafter, the multivariable regression analysis was performed using only the variables that had a p-value of 0.2 or less in the univariable analysis.Results In the univariable analysis, temporal bone fracture, diabetes mellitus, and BPPV side showed relatively significant association with the number of CRPs (p<0.2). In the multivariable analysis, only temporal bone fracture showed a significant association with the number of CRPs (p=0.043, β=0.532, 95% CI: 0.017-1.046).Conclusion The major finding of this study is that BPPV, accompanied by temporal bone fracture, precipitated more resistance to CRPs than idiopathic BPPV did. Thus, patients with temporal bone fracture might need more intensive examination and treatment for BPPV than those without temporal bone fracture.
Peroxiredoxin 2 Inhibits Lipopolysaccharide Induced Mucin Expression and Reactive Oxygen Species Production in Human Airway Epithelial Cells
Authors: Kim Joon-Hee , Jo Sooyeon , Lee Sangjae , Yoo Gi Moon , Na Hyung Gyun , Choi Yoon Seok , Bae Chang Hoon , Song Si-Youn , Kim Yong-Dae
Published: August 2021

Background and Objectives Peroxiredoxin (Prx) is an antioxidant enzyme involved in signaling pathway. Prx2 is the most abundant in mammalian gray matter neurons and has protective role under oxidative stress. MUC5AC and MUC5B are typical mucin genes in human airway epithelial cells. Even if free radicals play a key role in chronic respiratory inflammatory diseases, the effects of the Prx2 on mucin expression and oxidative stress are not clearly known. The purpose of this study is to investigate the effect of Prx2 on lipopolysaccharide (LPS)-induced MUC5AC/5B expression and reactive oxygen species (ROS) in human airway epithelial cells.Subjects and Method In NCI-H292 cells and human nasal epithelial cells, the effects of Prx2 on LPS-induced MUC5AC/5B expression and ROS production were investigated using reverse transcriptase-polymerase chain reaction, real-time polymerase chain reaction, enzyme linked immunosorbent assay (ELISA) and flow cytometry analysis.Results MUC5AC, MUC5B mRNA expression and protein production were increased by LPS. ROS production was also increased by LPS. Prx2 suppressed the LPS-induced MUC5AC mRNA expression and protein production as well as ROS production. However, Prx2 did not inhibit MUC5B mRNA expression and protein production. N-acetylcysteine, diphenyleneiodonium, and apocynin also inhibited LPS-induced ROS production.Conclusion These results may show that Prx2 suppresses LPS-induced MUC5AC expression via ROS in human airway epithelial cells.
Markovian Approach to Stock Price Modelling in the Nigerian Oil and Gas Sector
Authors: Ayo Adekunle S. , Uwabor Eboigbe S.
Published: August 2021

The study investigates the stock price movement of quoted Nigerian oil and gas firms using the Markovian model. Specifically, the study estimates the change in likelihoods and steady-state distribution of the share prices of the firms to determine the average time spent by the share price to move to another state and the turnover rate of the selected stocks. Markov chain-based stochastic modelling approach was employed by using the daily closing share prices of all the seven oil and gas firms quoted on the Nigerian Stock Exchange from April 2017 to January 2020. The study finds that the transition probabilities and the steady-state distribution of all the firms are stationary at first-order, implying that chain depends on the previous state. The steady-state probabilities of all the firms examined exhibit relatively high price stability in the long run. The study recommends that investors with diverse attitudes to risk-taking can explore the estimated long-run prospect of the investigated stocks in making guided investment decisions.
Analysis of Reinforcement System (Rock Bolt and Shotcrete) Effect on The Pillars Strength in Underground Mining Using Physical Models Testing in Laboratory
Authors: Dzakir La Ode , Rai Made Astawa , Widodo Nuhindro Priagung
Published: August 2021

The effects of reinforcement system on pillars were tested in laboratory, using three types of pillars with different strengths. The tests were performed using the UCS machine, to test pillar without reinforcement, pillar with rock bolt reinforcement, pillar with shotcrete reinforcement and pillar with the combination of both rock bolt and shotcrete reinforcement. Uniaxial compressive strength (UCS) testing aims to determine the effects of the reinforcement system on pillar strength. The results of this study indicate that the reinforcement system on high strength pillars causes a strength increase of 14.93% on pillar with rock bolt reinforcement, 21.45% on pillar with shotcrete reinforcement and 34.67% on pillar with combination of rock bolt and shotcrete reinforcement. On medium strength pillars, reinforcement installation shows a strength increase of 16.27% on pillar with reinforced rock bolt, 19.83% on pillar with reinforced shotcrete and 44.40% on pillar with combination of rock bolt and shotcrete reinforcement. Likewise, on low strength pillars, reinforcement installation causes a strength increase of 13.13% on pillar with reinforced rock bolt, 36.21% on pillar with reinforced shotcrete and 53.85% on pillar with combination of rock bolt and shotcrete reinforcement. The results of laboratory testing and numerical modeling indicate that the increase in strength occurs because the horizontal displacement on the surface of the pillar wall is detained by shotcrete and faceplate on rock bolt, so that the pillar seems to have confining pressure throughout the pillar wall surface, which is called as equivalent confining pressure.
Korelasi Point Load Index dan Uniaxial Compressive Strength pada Satuan Batupasir dan Batulempung Formasi Latih untuk Penentuan Koefisien Kekuatan Batuan di Pit X Tambang Batubara PT Berau Coal, Kalimantan Timur
Authors: Adriansyah Yan , Krisnantara Guruh , Setiadi Kurniawan
Published: August 2021

Physical and mechanical properties of rock for engineering purposes are indispensable for any civil/construction, mining and other engineering requirment. The results of the uniaxial compressive strength (UCS) test are very much needed in various geotechnical analyzes or engineering, in particular in the mining industry in relation to the calculation of the pit slope design and other mining infrastructure. Rock samples used in this study were obtained from the results of geotechnical drilling (full core drilling). The rock engineering properties test to obtain UCS and PLI values was carried out in the laboratory. Testing the rock hardness index using the point load index (PLI) can be done more quickly, cheaply, practically and can use rock samples with a variety of sample shapes.         The focus and object of the research are mudstone and sandstone units as part of the Lati Formation. These two types of layers are the most dominant rock types as a constituent of the pit slopes in the research area. To ensure that the correlation results are in accordance with the rules of scientific research, the distribution of UCS and PLI data from laboratory test results is verified using a statistical approach / testing. Correlation and analysis between the two rock engineering properties test results are very useful for geotechnical analysis data input. The coefficient or constant values obtained can be used to determine the rock strength values used in various geotechnical analyzes so that the analysis can be carried out more efficiently, effectively and quickly and can support geotechnical engineering work.
DOES HUMAN RESOURCES DEVELOPMENT AND ORGANIZATIONAL CULTURE STILL IMPACT ON EMPLOYEE PERFORMANCE?
Authors: Sulastini Hj.
Published: August 2021

This study aims to analyze (1) the effect of human resource development on employee performance, (2) ) The Influence of Organizational Culture on Employee Performance (3) The Influence of Human Resource Development and Organizational Culture on Employee Performance. The object of this research is PT.Sega Mas Banjarmasin. This study uses a survey method with a cross section design. The sampling technique uses saturated side (census). Respondents in this study were 40 permanent employees at PT.Sega Mas-Banjarmasin. This research resulted in the findings that by developing education and training, work capacity, knowledge skills, skills abilities, attitudinal abilities of employees organizational goals were achieved. Human Resource Developmentis a way to achieve an organizational goal effectively and efficiently through the implementation of individual duties and obligations in the organization. The findings of this study seem to enrich understanding of how to improve organizational performance through the inculcation of an effective Organizational Culture. This study found that the Organizational Culture that is built by increasing the culture of innovation, employee-oriented organizational activities and also paying attention to existing problems have implications for employee serenity and performance
VALUE ADDED MODEL OF COCONUT PROCESSING INDUSTRY (CASE STUDY)
Authors: Zhia Nurfajriah , Mahfud Halim , Purabaya Rudhy Ho
Published: August 2021

Coconut commodity has a strategic value because it has an important role in the economy, society and culture of Indonesian society. Coconut plant is a multipurpose plant where all parts of the plant have economic value, one of which is coconut husk. The potential of coconut coir is very large and has not been used optimally. Whereas coconut coir, when processed, will produce various products such as home industries, furniture, geotextiles, boards, and creative industries. This study is aimed at analyzing the potential development of the coconut coir processing industry and the added value that will be generated using the case study method and the location selection is done deliberately (purposive sampling). The business financial feasibility model obtained is a predictive model for analysis and planning of business financial feasibility through the NPV, IRR, PBP, BCR criteria with various scenarios of changes in prices, interest rates, and production scale.The business balance model obtained is a predictive model that can be used to analyze the price gap level to plan the price level that will provide proportional profit to produce coconut coir processing factory business. Based on the results of the verification of the model with input using the assumption of parameter values, it shows that the coconut coir processing industry is feasible to run.
DECISION MAKING ANALYSIS OF AUTO-ID SYSTEM USING ANALYTICAL HIERARCHY PROCESS (AHP) AT PT. AKG
Authors: Akbar Rezananda Yulian , Hisjam Muhammad
Published: August 2021

The increasingly competitive industrial competition makes companies from all sectors around the world change the system to be more efficient and effective. One of the efforts to improve the company is by implementing a Warehouse Management System (WMS). Lately, many large companies are implementing Auto-ID (automatic identification) technology to solve existing problems. The types of Auto-ID technology that are often used are barcode, RFID and QR code technology. PT AKG is a manufacturing company that produces and markets plastic finished materials to serve the needs of other companies has not yet implemented WMS, this causes human error due to the process still manual. This research proposed to find the best warehouse management system using the Analytical Hierarchy Process (AHP) method for PT. AKG. Alternative systems in this study are barcode, RFID, and QR code with the criteria used are cost, fuctionality, performance, and sustainability. Based on the results, the system chosen is the QR code with a score of 0.578084. QR codes can make it easier for operators and PPIC department staff to take notes and minimize recording errors. Recording that originally used Microsoft Excel and paper as a tool is no longer needed because operators only need to scan using a smartphone that is connected to the company's warehouse management system.
SUPPLY CHAIN RISK ANALYSIS IN KUB – IK MATARAM MACOA WITH HOUSE OF RISK (HOR)
Authors: Padhil Ahmad , Chairany Nurul , Ahmad Arfandi , Ramli Hardianti , Malik Rahmaniah
Published: August 2021

(KUB - IK ) Mataram  Macoa is a cocoa industry . The cocoa industry can produce chocolate with a cocoa material capacity of 87 kg per month or 1.0444 tons per year. Based on data from the Polewali Mandar Regency Statistics Agency, in 2018 the chocolate industry has a prospect that is still less proven with the data from BPS Polewali Mandar Regency, there is only 1 group of cocoa industry centers and the number of business units is 1 unit (BPS Polewali Mandar Regency, 2018).The company does not currently have a structured risk management to identify and mitigate risks that occur, especially in the supply chain function. By using the House of Risk method, the risks that may arise and their causes can be identified to simultaneously find ways to mitigate these risks to improve the operational quality of the Kelompok Usaha Bersama Industri Kecil Mataram Macoa  and open opportunities to detect profitable business opportunities for the company. The purpose of this paper is to determine the causes of the dominant risk and design response measures in the Kelompok Usaha Bersama Industri Kecil Mataram  Macoa. The basic method of writing is descriptive method and is implemented by using a case study method through a quantitative approach. The selection of respondents was carried out using purposive sampling technique. Methods of data collection by observation, in-depth interviews, questionnaires and literature study. The results of this paper indicate that in the activity plan there are 2 risks, in source activity there are 5 risks, in make activities there are 5 risks, in delievery activities there are 3 risks, and in return activities there is 1 risk. The risk treatment plan is designed to reduce the risk status for each risk event using a risk matrix
EVALUATION OF WORK POSITION USING SUBYECTIVITY APPROACH BASED ON RULA METHOD
Authors: Hanafi Ahmad
Published: August 2021

Workers' activities basically have a positive and negative impact, one of which is the result of a disturbed skeletal and muscular system, which is a decrease in the strength level of body parts which constitutes work productivity when carrying out daily activities. Knowing the danger level of body posture carried out by the welding position, so that it can be given useful input for the company's progress. The method used is the Rapid User Limb Assessment (RULA) method carried out on welding workers and the research method quantitatively and qualitatively then carried out statistical analysis, subjectivity and rula. The results showed that the final score of the posture of squatting, sitting and sitting in a chair had a score of 7, which means a high level of risk and needs immediate improvement. After evaluating the welding position improvement, there is a seat posture with a score of 3 which is a low risk level and requires changes. Same with the welding position sitting on the chair. The squat welding position with a score of 4 which is a low level risk level and sitting work posture has a score of 4 which means a low risk level, but requires a change for the future. From this study it was found that the relationship between Nordic Body Map and RULA was a continuity in squat work postures, which was found that this work posture had the highest risk of danger. Need to improve work posture in certain welding positions in this project or provide counseling about the dangers of work in the work posture if it continues
Antipredatory strategies of leatherback sea turtles during internesting intervals on St. Croix, US Virgin Islands
Authors: Asada A , Eckert SA , Hagey WH , Davis RW
Published: August 2021

Predators affect prey through mortality, and prey respond by employing antipredatory strategies. Although leatherback sea turtles Dermochelys coriacea are the largest sea turtle, they are susceptible to shark predation. Females lay multiple clutches of eggs separated by a ~10 d internesting interval at sea, during which they move many kilometers away from the nesting beach. The goal of this study was to test the hypothesis that this wide-ranging behavior was associated with predator avoidance. To accomplish this goal, we used animal-borne video and data recorders along with satellite telemetry to monitor diving behavior and track the at-sea movements of females during the internesting intervals on St. Croix, US Virgin Islands. After they departed the nesting beach, females immediately swam a mean maximum distance of 101 km from St. Croix. The mean transit distance during 10.19 d at sea was 466 km. We recorded 102 periods during which females inverted and rotated vigorously for an average of 2.7 min at or near the surface. Because females nesting on St. Croix commonly exhibit scars and fresh wounds, many of which result from shark encounters, this behavior likely represents a defensive response to predator attack. The frequency of defensive behaviors that occurred <6 km from the nesting beach (4.6 d-1) was 3.3-fold greater than when they were >6 km from shore (1.4 d-1). By moving offshore, females reduced the possibility of predator encounters by 53%.
Functional Training Effect on Functional Movements and Physical Capacity in 10 to 13-Year-Old Children Attending Swimming Activities
Authors: Budrienė Lina , Karpavičiūtė Vaida , Dudonienė Vilma
Published: August 2021

Background. Functional training is used both in rehabilitation - to restore lost functions, and in professional sports - to improve results in competitions. Functional training is characterized by complex training of physical features, and it develops specific movements.

The aim was to evaluate functional training effect on functional movements, static endurance of trunk muscles and dynamic balance in children aged 10 to 13 attending swimming activities.

Methods. The study involved 24 children in the age group of 10–13 who attended swimming activities 5 times a week. Subjects were randomly divided into two groups: subject (n = 12) and control (n = 12). Participants of the subject group while attending regular swimming activities were prescribed functional training of 10-week once a week with supervision of a physiotherapist. The participants of the control group while attending regular swimming activities were prescribed a routine swimmer training of 10-week once a week in the gym under the supervision of a sports coach. Static endurance, dynamic balance, leg muscle’s explosive force and swimming competition results corresponding to the time interval of the beginning and end of the study were assessed before and after the interventions.

Results. All the evaluated indicators had tendency to improve, but significant differences between the results of the two groups were found in the static endurance of the abdomen and trunk lateral muscles, dynamic balance, functional movements, long jump results and 50-meter swimming results.

Conclusion. Functional training under the supervision of a physiotherapist can significantly improve the functional and physical capacity of children attending swimming activities.

Keywords: physical characteristics, functional training, endurance, balance, functional movements.
Kojų raumenų stiprinimo ir tempimo pratimų poveikis moterų plokščiapėdystės simptomams, pusiausvyrai bei gyvenimo kokybei
Authors: Turauskaitė Inesa , Žlibinaitė Laura
Published: August 2021

Tyrimo pagrindimas. Nustatyta, kad sutrumpėjusių struktūrų tempimo bei nusilpusių raumenų stiprinimo pratimai gali sumažinti plokščiapėdystės simptomus. Visgi, neaišku, kaip kojų raumenų tempimo ir stiprinimo pratimai paveikia moterų plokščiapėdystės simptomus, pusiausvyrą bei gyvenimo kokybę.

Tikslas – nustatyti kojų raumenų stiprinimo ir tempimo pratimų poveikį moterų plokščiapėdystės simptomams, pusiausvyrai bei gyvenimo kokybei.

Metodai. Tyrime dalyvavo 16 moterų (amžius 28,19 ± 7,77 metų), turinčių plokščiapėdystės požymių. Tiriamosios atsitiktine tvarka buvo priskirtos į vieną iš dviejų grupių: kojų raumenų stiprinimo arba tempimo pratimų grupę. Kineziterapija vyko nuotoliniu būdu keturias savaites, penkis kartus per savaitę, vieno užsiėmimo trukmė – 30 min. Prieš ir po intervencijų buvo vertinama statinė ir dinaminė pusiausvyra, vidinis išilginis pėdos skliautas bei gyvenimo kokybė.

Rezultatai. Tiek po kojų raumenų stiprinimo, tiek po tempimo pratimų pakilo vidinis išilginis pėdos skliautas, pagerėjo pusiausvyros bei gyvenimo kokybės rodikliai (p < 0,05). Palyginus rezultatus tarp grupių, reikšmingo skirtumo nenustatyta nė vienam rodikliui.

Išvada. Kojų raumenų stiprinimo arba tempimo pratimai gali būti taikomi kaip veiksminga konservatyvi priemonė, kuri mažina moterų plokščiapėdystės simptomus, gerina pusiausvyrą ir gyvenimo kokybę.

Raktažodžiai: plokščiapėdystė, pratimai, pusiausvyra, pėdos skliautas, gyvenimo kokybė.
4–6 metų vaikų motorinių gebėjimų ir kognityvinių funkcijų sąsaja su kūdikystės bendrosios motorikos ropojimo funkcija
Authors: Urvikytė Silvija , Dudonienė Vilma
Published: August 2021

Tyrimo pagrindimas. Ropojimo raidos etapas kūdikystėje palengvina kūno padėties suvokimo vystymąsi, o vėliau ir motorinių įgūdžių vystymąsi, taip pat lavina atmintį, pagerina kognityvinę bei socialinę raidą (Xiong ir kt., 2018).

Tikslas – nustatyti vaikų motorinių gebėjimų ir kognityvinių funkcijų sąsajas su bendrosios motorikos ropojimo funkcija.

Metodai. 22 sveiki tiriamieji (4–6 metų amžiaus) pagal tėvų pateiktos apklausos atsakymus, suskirstyti į dvi grupes: nepraleidusius ir praleidusius ropojimo raidos etapą kūdikystėje. Visiems tiriamiesiems buvo vertintas funkcinis liemens stabilumas, pusiausvyra, koordinacija (šokinėjimas įvairiomis kryptimis, kamuolio gaudymas ir kamuolio spyrimas) bei kognityvinės funkcijos.

Rezultatai. 85 proc. ropojusių vaikų turėjo funkciškai nestabilų liemenį, neropojusiųjų grupėje – 78 proc., skirtumas statistiškai reikšmingas. Kūdikystėje ropojimo nepraleidę vaikai pusiausvyrą bandė išlaikyti vidutiniškai tris kartus, ropojimą praleidę – 10 kartų (p < 0,05). Vertindami koordinacinių gebėjimų užduočių atlikimą, nustatėme, kad tiek kūdikystėje ropojusių, tiek neropojusių vaikų šokinėjimo įvairiomis kryptimis ir kamuolio metimo koordinacija vertinama gerai, tačiau kamuolio spyrimo – patenkinamai. Ropojusių (89 proc.) ir neropojusių (78 proc.) vaikų dėmesio pastovumas vertinamas, atitinkamai – labai geras ir geras. Kūdikystėje nepraleidusių ropojimo vaikų raidos etapo grupėje, kamuolio gaudymas buvo tiesiogiai ir vidutiniškai stipriai susijęs su kamuolio spyrimo užduotimi (r = 0,556; p = 0,048).

Išvados. Tiriamieji, kurie kūdikystėje praleido ropojimo raidos etapą, atsistojo anksčiau. Vaikai, nepraleidę ropojimo raidos etapo kūdikystėje, pasižymėjo geresne pusiausvyra, tačiau koordinaciniai gebėjimai, funkcinis liemens stabilumas bei gebėjimas koncentruoti dėmesį nesiskyrė nuo vaikų, kurie kūdikystėje praleido ropojimo funkciją

Raktažodžiai: vaikų motoriniai gebėjimai, kognityvinės funkcijos, ropojimas.
Clinical and functionai efficiency of several large joints arthroplasty in patient with rheumatoid arthritis
Authors: Lapshina S. A. , Akhtyamov I. F. , Gilmutdinov I. Sh. , Volchenko D. V.
Published: August 2021

The article presents the issues of arthroplasty of several large joints in rheumatoid arthritis (RA), including the difficulties of perioperative management of young patients. The effectiveness of arthroplasty of several (from 2 to 4) large joints is shown in the management of patients with RA at the orthopedist and rheumatologist. Тhe absence of serious postoperative complications was demonstrated. The article presents а 20-year clinical case of a young patient with active RA and arthroplasty of 4 large joints. This example demonstrates the success and safety of multiple arthroplasty with a complete return of joint function and a decrease in RA activity during long-term dynamic follow-up at the orthopedist and rheumatologist.
Determination of body fat percentage by bioelectrical impedance analysis and dual-energy X-ray absorptiometry
Authors: Nikitinskaya O. A. , Toroptsova N. V.
Published: August 2021

Obesity is a risk factor for many chronic diseases. Several research methods are used to determine the amount of body fat, including the «gold standard» dual-energy X-ray absorptiometry (DXA). The bioelectrical impedance analysis (BIA) method is an alternative for assessing body composition that does not require special conditions for placement and examination, but the accuracy of its results depends on the hydration of the body.

Objective. To compare the results of determining the percentage of body fat using multi-frequency (MF) BIA and DXA.

Material and methods. The study included 20 volunteers (11 women and 9 men) aged 26 to 70 years without serious metabolic, cardiovascular or endocrine diseases. Two repeated measurements were performed using the MF-BIA method on the MS FIT device and the DXA method on the Lunar Prodigy Advance device.

Results. There were no significant differences in the average percentage of body fat in repeated measurements by MF-BIA and DXA methods, and the intra-group correlation coefficients (r2 ) were 0.999 and 0.997, respectively. A high and significant correlation in percentage of body fat was found between the MF-BIA and DXA (r = 0.973, p < 0.001). The average difference between the results of these two methods was 0.1243%. Differences in percentage of body fat that exceeded two or more standard deviations were detected less than in 5% cases, so the data on body fat content estimated using DXA and BIA are consistent and can be considered almost equal.

Conclusion. Our study has shown that the MS FIT body composition device using the MF-BIA method can be an alternative to DXA for assessing the percentage of body fat without introducing additional formulas to recalculate the data obtained.
Possibilities of personalized approach to genetically engineered biological therapy of rheumatoid arthritis
Authors: Shilova L. N. , Spitsina S. S.
Published: August 2021

Rheumatoid arthritis is the most common rheumatic disease characterized by damage to the synovium, progressive destruction of cartilage and bone tissue. As a result of the establishment of the biological role of cytokines, it became possible to intervene in the main links of the pathogenesis of the disease, which led to inhibition of the main pathological process in RA – autoimmune inflammation.

The aim. To consider the possibilities of optimizing the biological therapy of rheumatoid arthritis by identifying predictors of anti-inflammatory efficacy among clinical and laboratory markers.

Basic provisions. Despite the success of genetically engineered biological drugs in the treatment of inflammatory arthritis, due to the lack of predictive biomarkers, the use of a trial and error approach, empirical therapy, is inevitable, which does not always lead to satisfactory results. The study of the main biomarkers of RA provides new insights into their potential association with various clinical phenotypes.

Conclusion. This patient-centered approach offers the prospect of improving treatment outcomes through the use of specific drugs in certain patient groups.
Itch in Hymenoptera Sting Reactions
Authors: Cerpes Urban , Repelnig Maria-Lisa , Legat Franz J.
Published: August 2021

Insect stings and the resulting itch are a ubiquitous problem. Stings by members of the insect order Hymenoptera, which includes sawflies, wasps, bees and ants, and especially by bees and wasps are extremely common, with 56–94% of the population being stung at least once in their lifetime. The complex process of venom activity and inflammation causes local reactions with pain and pruritus, sometimes anaphylactic reactions and more seldomly, as in case of numerous stings, systemic intoxication. We reviewed the literature regarding itch experienced after Hymenoptera stings, but found no study that placed a specific focus on this topic. Hymenoptera venoms are composed of many biologically active substances, including peptide toxins and proteinaceous toxins. Peptide toxins from bee venom cause cell lysis and ion channel modulation in the peripheral and central nervous systems, while toxins from wasp venom induce mast cell degranulation and chemotaxis of polymorphonuclear leukocytes in the skin. The proteinaceous toxins cause a disruption of the cell membranes and necrotic cell death, degradation of hyaluronan (an extracellular matrix glycosaminoglycan), increased vascular permeability, hemolysis, as well as activated platelet aggregation. Mediators which could be directly involved in the venom-induced pruritus include histamine and tryptase released from mast cells, interleukin-4 and interleukin-13 from Th2 lymphocytes, as well as leukotriene C4. We postulate that a pruriceptive itch is induced due to the pharmacological properties of Hymenoptera venoms.
Purification of Modified Therapeutic Proteins Available on the Market: An Analysis of Chromatography-Based Strategies
Authors: Sánchez-Trasviña Calef , Flores-Gatica Miguel , Enriquez-Ochoa Daniela , Rito-Palomares Marco , Mayolo-Deloisa Karla
Published: August 2021

Proteins, which have inherent biorecognition properties, have long been used as therapeutic agents for the treatment of a wide variety of clinical indications. Protein modification through covalent attachment to different moieties improves the therapeutic’s pharmacokinetic properties, affinity, stability, confers protection against proteolytic degradation, and increases circulation half-life. Nowadays, several modified therapeutic proteins, including PEGylated, Fc-fused, lipidated, albumin-fused, and glycosylated proteins have obtained regulatory approval for commercialization. During its manufacturing, the purification steps of the therapeutic agent are decisive to ensure the quality, effectiveness, potency, and safety of the final product. Due to the robustness, selectivity, and high resolution of chromatographic methods, these are recognized as the gold standard in the downstream processing of therapeutic proteins. Moreover, depending on the modification strategy, the protein will suffer different physicochemical changes, which must be considered to define a purification approach. This review aims to deeply analyze the purification methods employed for modified therapeutic proteins that are currently available on the market, to understand why the selected strategies were successful. Emphasis is placed on chromatographic methods since they govern the purification processes within the pharmaceutical industry. Furthermore, to discuss how the modification type strongly influences the purification strategy, the purification processes of three different modified versions of coagulation factor IX are contrasted.