bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring Challenges and Prospects of Solar Energy Entrepreneurship of Accra Metropolis in Ghana
Authors: Opoku Oscar Agyemang , Ebo Sampson Lord , Okudzeto Henry , Azebiik Anak Jesse
Published: February 2022

The demand for power in Ghana is increasing at a pace of 10% each year. To shift away from traditional energy-intensive economic development and its negative environmental impact, the government has begun to heavily promote the development of solar photovoltaic technology. This study explored the challenges and potential of solar energy entrepreneurship as well as the capacity of solar energy enterprises in the production and supply of solar energy, and the methodologies for implementing solar energy businesses in Ghana's Accra Metropolis. The research took a qualitative approach and used an exploratory design. The data were analysed thematically with the aid of NVivo version 11.0. In comparison to predicted market demands, solar energy firms did not have the resources to produce and supply solar energy. In addition, to promote their operations in Ghana, solar energy companies have used techniques such as discounts, installment payments, and price reductions for goods and services. Furthermore, high-interest rates, inadequate incentives, insufficient access to finance, and a lack of technical know-how for the operation and maintenance of solar energy technology were all obstacles to investment in solar energy generation. Notwithstanding the difficulties associated with its operations, the prospects for solar energy production in Ghana remain bright. The study recommended that the Ministry of Energy, in collaboration with renewable energy technology companies, educate the public about the benefits of solar energy technologies; the Ministry of Energy, in partnership with the government, ensure that the promise made in the energy policy of a 50% tax reduction on all imports of electrical goods is achieved. Moreover, financial institutions should make it easier for energy-producing firms to obtain credit.
PELATIHAN PEMANFAATAN MEDIA ONLINE SEBAGAI SARANA PENGEMBANGAN USAHA BAGI KOMUNITAS KULINER SEHATI
Authors: Yusa Viola De , JL Ana Risqa
Published: February 2022

Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk menambah dan mngembangkan pengetahuan tentang pemanfaatan media online sebagai sarana pengembangan usaha bagi komunitas Kuliner Sehati agar bisa mewujudkan ke arah yang lebih mandiri secara ekonomi dan mampu bersaing secara unggul dalam dunia usaha, maka tim memberikan materi dan pelatihan tentang pengembangan usaha melalui media online. Hasil dari pengabdian pada masyarakat yang telah dilaksanakan dengan menggunakan metode ceramah dan metode diskusi. Metode ceramah kegiatan terdiri dari penyampaian materi tentang pemasaran secara online, pemahaman terhadap media online, serta trik dan tips dalam usaha menggunakan media online seperti instagram, Facebook dan lain-lain. Metode diskusi kegiatan yang dilakukan sistem tanya jawab terhadap komunitas serta praktek dalam membuat akun Instagram untuk mempromosi usahanya. Berdasarkan hasil pengabdian, maka dapat disimpulkan bahwa dengan adanya pelatihan ini maka menjadi wadah bagi komunitas Kuliner Sehati yang ingin mengekspresikan hobby dan kecintaannya tentang semua hal berhubungan dengan makanan dan kuliner menjadi awal dari terbentuknya usaha.
PENINGKATAN KUALITAS SDM MELALUI KETRAMPILAN IPTEK DAN PEMBUATAN LAPORAN KEUANGAN SEDERHANA DI PAUD FLAMBOYAN BANDUNG
Authors: Kuraesin Aneu , - Suryaman , - Rukamana
Published: February 2022

Kegiatan pengabdian ini bertujuan untuk meningkatkan dan mengaplikasikan kemampuan dan keahlian sebagai dosen dalam wujud pemenuhan pengabdian kepada masyarakat sebagai bagian dari kewajiban tridharma perguruan tinggi. Pengabdian ini khususnya diberikan kepada staf dan guru guru di PAUD Flamboyan Kota Bandung. Pengabdian ini diberikan untuk meningkatkan kemampuan Sumber Daya Manusia dibidang Ilmu dan Teknologi di PAUD Flamboyan khususnya penggunaan pemakaian perangkat IT sederhana yang sudah dibuatkan softwarenya dan pembuatan laporan keuangan sederhana. Setelah pengabdian maka dapat disimpulkan bahwa (1) staf dan guru dapat memahami ilmu Teknologi sederhana (2) dapat membuat laporan keuangan sederhana yang baik dan benar.
PENINGKATAN KEMAMPUAN PRODUKSI PADA KELOMPOK USAHA MANUFAKTUR LOGAM
Authors: Ndaruhadi P.Y.M. Wibowo , Rosihan War’an , Paramita V. Santi
Published: February 2022

Keterbatasan dan kemampuan sumber daya yang dimiliki oleh usaha mikro seringkali menjadi masalah krusial dalam keberlangsungan operasional usahanya. Tujuan dari kegiatan pengabdian masyarakat melalui program kemitraan masyarakat ini adalah untuk meningkatkan kemampuan produksi pada kelompok usaha manufaktur logam. Bengkel Kembang Sore dan CV Egindo merupakan dua usaha mikro di daerah Cisangkan dan Gunung Batu - Cimahi yang bergerak dalam bidang pemesinan digandeng sebagai mitra pada program ini. Kegiatan utama dalam pelaksanaan program ini adalah pelatihan teori dan praktik dalam aspek teknikal dan manajerial serta dikuatkan dengan kegiatan pendampingan di lapangan. Aspek teknikal difokuskan pada bidang pengelolaan pahat sebagai perkakas potong dalam operasi pemesinan. Dukungan lain yang diberikan adalah penambahan fasilitas pendukung dalam operasi pemesinan, yaitu berupa fasilitas penggerindaan atau pengasahan pahat yang diperlukan. Kelancaran dan keberhasilan program ini sangat dipengaruhi oleh kerjasama dan tingkat partisipasi aktif dari mitra selama pelaksanaan semua kegiatan. Evaluasi dan pendampingan yang berkelanjutan serta penguatan dukungan bidang yang lain seperti desain dan penggunaan perangkat lunak adalah diperlukan dalam kegiatan berikutnya dalam koridor mitra binaan.
BANTUAN SOFTWARE SISTEM PENCATATAN AKUNTANSI PADA USAHA BANANA PAPER SADANG SERANG – COBLONG - BANDUNG
Authors: Kasim Erlynda Yuniarti , Rusyandi Deddy , Garibaldi Ganjar
Published: February 2022

Kegiatan Pengabdian ini bertujuan untuk membantu Mitra dalam menyelesaikan permasalahan pencatatan akuntansi dengan memberikan Software Aplikasi Pencatatan Akuntansi yang dikembangkan sendiri oleh Tim dengan harapan mitra dalam hal ini “Banana Paper” yang berlokasi di Jl. Sadang Serang No 8 Kecamatan Coblong Kota Bandung dapat mengaplikasin software ini agar dapat menyelesaikan salah satu masalah dalam mencatat transaksi akuntansi dan memberikan dampak positif terhadap kemajuan usaha Banana Paper. Setelah dilakukan pelatihan cara mengaplikasikan software Aplikasi Pencatatan Akuntansi, mitra kini dapat menhasilkan laporan keuangan seperti neraca dan Laba rugi dengan hanya meng-inputkan kegiatan transaksi yang terjadi, dengan sedikit catatan bahwa mereka harus lebih memahami memahami penomoran akun dan pengelompokan akun debit dan akun Kredit.
PENERAPAN MANAJEMEN KEUANGAN SEDERHANA, PENGUKURAN BIAYA PRODUKSI DAN PENGEMBANGAN PASAR PADA PERUSAHAAN KERUPUK DAN BASRENG “D’ RISA” (DRS) KABUPATEN BANDUNG
Authors: Supriyanto Dodi , Taufiqurrochman Cecep
Published: February 2022

Sudah menjadi rahasia umum bahwa dalam usaha UMKM itu banyak sekali kelemahan-kelemahana dalam berbagai sisi. Kelemahan yang paling menonjol dalam kegiatan UMKM itu adalah lemahnya dalam pencatatan keuangan, tidak jelasnya tata kelola karena tidak menggunakan fungsi manajemen dan belum bisa dipisahkan antara harta perusahaan dengan harta pemiliknya. Untuk mengurangi permasalahan dalam UMKM itu antara lain dengan memberikan sosialisasi dan pelatihan tentang penerapan manajemen keuangan, pengukuran biaya produksi dan Pengembangan Pasar. Pengabdian ini menggunakan metode deskriftif melaluikunjungan langsung ke lapangan dan wawancara, hal ini adalah untuk mengetahui gambaran objek yang diteliti secara nyata sesuai dengan kondisi yang ada di lapangan. Dalam pengumpulan data dilakukan dengan wawancara dan on the spot langsung ke objeknya. Disamping itu, dilakukan penelitian kepustakaan.

Berdasarkan hasil pengabdian kepada masyarakat menunjukan bahwa kegiatan usaha ini belum sepenuhnya menggunakan penerapan manajemen keuangan sederhana, pengukuran biaya produksi tidak dilakukan dan tanpa catatan serta pengembangan pasar masih dilakukan dengan cara konservatif. Namun demikian, omset usahanya terus meningkat baik dari produksi baso goreng dan kerupuknya.. Pasar yang sudah di jangkaunya adalah pasar Rangkas Bitung, Tangerang dan Karawang.Penjualan dilakukan cash and carry atau pembayaran dengan waktu tangguh 1 minggu, dimana pembayarannya via bilyet giro atau cek. Dapat disimpulkan bahwa pemasaran yang dilakukan masih tradisional.
PELATIHAN PENYUSUNAN LAPORAN KEUANGAN DAN PERENCANAAN STRATEGI PEMASARANPADA UMKM CLOTHING – UNSCARRED
Authors: Prawirasasra Kannya , Maulani Terra Saptina
Published: February 2022

Kota Bandung merupakan salah satu kota kreatif di dunia, hal tersebut ditandai dengan berkembangnua industri kreatif di berbagai bidang. Salah satu sektor yang paling berpotensi adalah di bidang fashion, hal ini dibuktikan dengan meningkatnya pertumbuhan distro, clothing dan factory outlet. Salah satu clothing yang telah berdiri sejak tahun 2015 adalah UNSCARRED. Usaha ini masih tergolong UMKM, dengan target pasar nya adalah anak muda berbasis komunitas Skater. Semakin berkembangnya industri ini menimbulkan persaingan yang tidak dapat dihindarkan baik dari dalam kota maupun luar kota karena menyasar pasar yang sama, maka dari itu perlunya mempernahankan usaha agar tidak kalah persaingan dengan dilakukannya strategic marketing plan. Tidak hanya persoalan di bidang pemasaran, hambatan lain yang dihadapi oleh usaha ini adalah tidak adanya pencatatan keuangan yang sistematis dikarenakan minimnya pengetahuan mengenai keuangan, terbatasnya alat bantu dalam membuat laporan keuangan yang terdapat di pasaran memiliki harga yang relatif mahal, serta minimnya modal, mengakibatkan perusahaan tidak memiliki SDM yang berkompeten dalam menyusun laporan keuangan. Dengan dilakukannya pengabdian ini berupa Pelatihan Penyusunan Laporan Keuangan dan Perencanaan Strategi Pemasaran Pada UMKM Clothing – UNSCARRED dapat membantu pelaku usaha meningkatkan keterampilan sebagai bekal untuk bersaing.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PENGGUNAAN MASKER SAAT PANDEMI COVID-19 PADA MASYARAKAT DI PAKUSARI JEMBER
Authors: ACHMAD AFIFIL AFTON
Published: February 2022

Latar belakang: Penularan Covid-19 sangat mudah sekali menyebar dan merupakan sebuah penyakit yang menyebabkan pandemic berkepanjangan. Oleh karena itu penggunakan masker sangatlah dibutuhkan dan diperlukan guna memutus rantai penyebaran Covid-19. Penelitian ini bertujuan untuk mendeskrisikan faktor-faktor yang berhubungan dengan Penggunaan Masker Saat Pandemi Covid-19 Pada Masyarakat di Pakusari Jember.Metode: Penelitian ini menggunakan desain penelitian analitik kuantitatif dengan pendekatan cross sectional. Pengambilan sampel secara Purposive Sampling dengan jumlah responden yaitu sebanyak 100 responden.Hasil: Hasil penelitian menunjukan bahwa variable pengetahuan, pendidikan, dukungan keluarga, dan sikap warga mempunyai hubungan dengan Penggunaan Masker Saat Pandemi Covid-19 Pada Masyarakat di Pakusari Jember.Kesimpulan: Penggunaan masker sangat dibutuhkan oleh warga disaat pandemic seperti saat ini sehingga dibutuhkan kesadaran dari masyarakat agar masyarakat bisa menggunakan masker saat beraktivitas
ANALISIS FAKTOR YANG MEMPENGARUHI KUALITAS HIDUP PADA PASIEN DENGAN BREAST CANCER: LITERATURE REVIEW
Authors: SUHARTA, DWI AISYAH
Published: February 2022

Latar belakang: Breast cancer merupakan salah satu kanker yang paling umum pada wanita diseluruh dunia. Indonesia berada di urutan ke-8 di Asia Tenggara dan ke-23 Asia. Salah satu dampak paling nyata pada penderita breast cancer adalah penurunan kualitas hidup baik dari segi fisik atau psikososial.Metode: Data penelitian ini diambil dari empat database yang relevan seperti PubMed, Science Direct, EBSCO dan Google Scholar dengan menggunakan metode PIOS (Participant, Intervention, Outcomes and Study Design) dan istilah MeSH pada mesin pencarian. Kata kunci “kualitas hidup” or “quality of life” and “kanker payudara” or “breast cancer”. Data yang diambil adalah journal yang terbit tahun 2012-2021 berbahasa Inggris dan berbahasa Indonesia (open access dan full text) serta original article. Dari n= 3. 252 artikel yang di temukan, hanya n=10 yang memenuhi kriteria inklusi.Hasil: Hasil dari literature review ini menjelaskan bahwa terdapat beberapa faktor yang dinilai berpengaruh terhadap kualitas hidup individu breast cancer antara lain faktor dukungan (dukungan sosial dan dukungan keluarga), motivasi diri atau efikasi diri, gaya hidup, karakteristik demografi (umur, pekerjaan, tingkat pendidikan, sosial ekonomi) dan karakteristik klinis penderita breast cancer (Stadium penyakit dan status pengobatan (kemoterapi).Kesimpulan: Mengidentifikasi faktor tersebut sangat penting, guna merumuskan intervensi keperawatan yang lebih komprehensif, dimana hal ini diharapkan meningkatkan kualitas kesehatan fisik, psikis, maupun sosial pada individu breast cancer.
Pelaksanaan Timbangan dalam Jual Beli Ayam Potong di Tinjau Dari Perspektif Ekonomi Islam (Studi Kasus di Pasar Raya Amahami Kota Bima)
Authors: Wahyunti Sri , Setyani Eka
Published: February 2022

Penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif. Dengan tekhnik pengumpulan data observasi, dokumentasi, dan wawancara. Penelit melakukan pengecekan ulang terhadap data yang diperoleh dan menggunakan teknik triangulasi. Setelah itu, menganalisisnya melalui reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini dapat diketahui bahwa penerapan Ekonomi Islam terhadap praktek timbangan jual beli ayam potong di Pasar Raya Amahami belum diterapkan secara efektif.   Karena   ada beberapa pedagang yang belum sempurna dalam menggunakan timbangannya dalam menjual ayam potong.
Jual Beli Online dengan Sistem Dropship dalam Perspektif Islam
Authors: Fadhillah Nur , Alamin Zumhur
Published: February 2022

Seiring berjalannya waktu jual beli online mulai berkembang dalam hal model transaksinya seperti penggunaan sistem dropship. Jual beli dengan sistem dropship ini menjadi salah satu alternatif yang dipilih dikarenakan tidak memerlukan modal besar bahkan tanpa modal sekalipun.

Transaksi jual beli online dengan sistem dropship setelah dikaji dari sisi rukun dan syarat jual beli Islam telah memenuhi rukun akad dalam syariah. Sedangkan Pada sisi kepemilikan atas objek barang dalam praktik jual beli sistem dropship memiliki dua pendapat, yaitu: pertama, diperbolehkan dengan catatan penjual mendapatkan ijin dari pemilik barang dan penjual dapat menghadirkan barang tersebut. Kedua dilarang, karena penjual menjual barang bukan miliknya/ barang masih berada pada pemiliknya (supplier).
基于董事会特征角度下企业社会责任对财务绩效的影响 —以福耀集团为例
Authors: 蔡 浣萍 , 张 茖 , 蔡 兰英
Published: February 2022

本文以福耀集团为例，从董事会特征的角度（董事会规模、董事会独立性）对福耀集团的社会责任和财务绩效关系进行分析和检验。本文采用理论分析与实证检验相结合的研究方法。研究结果表明，企业社会责任对财务绩效具有显著的积极影响，且董事会规模越大、独立性越高，这种积极影响越大。
ON ONE METHOD OF PREDICTING THE RELATIVE HUMIDITY OF THE MINE AIR
Authors: Oniani Shurman , Lanchava Omar , BOLKVADZE Soslan
Published: February 2022

On the basis of the law of conservation of energy a differential equation of the balance of mass has been derived and solved for an elementary length of the underground working district. Formulae have been obtained for determining the relative humidity of the mine air for the circuit «of the workings.
CONCERNING THE THERMO-MOISTURE TRANSFER IN A MASSIF
Authors: Oniani Shurman , Lanchava Omar
Published: February 2022

A technique is proposed for determining the thermo-gradient coefficients on the basis of an analysis of the thermo-moisture transfer in rocks. The values of these coefficients are presented for some rocks.
Pertusaria wui sp. nov. on bamboo from Yunnan, China
Authors: Zhang Jiarong , Liu Lin , Xue Xiandong , Ren Qiang
Published: February 2022

A new species Pertusaria wui is described from bamboo in Yunnan Province, China. Diagnostic characters include a thin, shiny, off-white, continuous and crustose thallus, numerous (mostly conical) verrucae with punctiform ostioles, uniseriate ascospores of 47.5–62.5 ×
25–30 μm, 8-spored asci, and major lichen compounds lichexanthone and stictic acid.
Validation of five Peronospora species names
Authors: Davis William J. , Crouch Jo Anne
Published: February 2022

Some Peronospora names included in the last major taxonomic treatment (a 1991 annotated list of names) were invalid because the author failed to provide the Latin description required at the time of their proposal. Here five such names—Peronospora coronillae-minimae,
P . erini, P. papaveris-pilosi, P. ranunculi-flabellati, and P. viciicola—are validated either by providing an English description or by reference to the original English description.
First report of Podosphaera cercidiphylli on endangered Cercidiphyllum japonicum in China
Authors: Peng Zi-Jia , Liu Shu-Yan , Yu Zhong-Dong , Qi Mei
Published: February 2022

A powdery mildew collected from the protected and endangered species Cercidiphyllum japonicum was identified morphologically as Podosphaera cercidiphylli, an identification confirmed by sequence analyses of the internal transcribed spacer (ITS) and large subunit (LSU)
of nuclear ribosomal DNA (nrDNA). This is the first report of P. cercidiphylli in China.
Macromycetes from woodland zones of Milpa Alta mayoralty, Mexico City, Mexico
Authors: Sierra Sigfrido , Castro-Santiuste Sandra , Rodríguez-Gutiérrez Ibeth , González-Mendoza Areli E. , Gutiérrez-Sánchez Mario Aarón , Chávez-García Lisette , Guzmán-Ramírez Daniela Abigail , Ruiz-Ramos José de Jesús , Galván-Becerril Guadalupe , López-Garduza Navith Alejandra , Pérez-Ramírez Lilia , Cifuentes Joaquín
Published: February 2022

The beautifully illustrated 30-page "Macromycetes from woodland zones of Milpa Alta mayoralty, Mexico City, Mexico" by Sierra and eleven co-authors may now be downloaded from Mycotaxon's mycobiota webpage. This brings to 151 the number of free-access Fungae uploaded or linked to http://www.mycotaxon.com/mycobiota/index.html
Spectrophotometric Estimation of Iron (III) in Iron Polysaccharide Complex Capsule Formulation and its Accelerated Stability
Authors: Salman Zafar Salman Zafar , Farrukh Sier Farrukh Sier , Samiullah Samiullah , Gohar Ayub and Rahat Ullah Gohar Ayub and Rahat Ullah
Published: February 2022

Iron plays a pivotal role in human physiology, while its deficiency may prove fatal in severe cases. Analytical methods for the quantitative determination of iron are thus very important. Herein, we report the estimation of iron in iron Polysaccharide complex (IPSC) using raw material and formulations, through a spectrophotometric analytical method. IPSC capsules were formulated and their stability was studied by developing a simple and validated analytical method. The process is based on the acid hydrolysis of IPSC and the development of chromogen by reacting ammonium thiocyanate with IPSC, maximum absorption at 474 nm was observed. Beerand#39;s Lambert law (linearity response) was found in the range of 10-20 μg/ml with excellent correlation coefficient of determination (R = 0.998). The quantification and detection limits were established to be 0.45 mcg/ml and 0.14 mcg/ml correspondingly. The recovery of IPSC analysis was 99.25 to 102.28 %. Percentage assay of IPSC capsules showed results around 102.34 %. The formulated IPSC capsule was stable under accelerated conditions for 6 months (% assay andgt; 91.69). The dissolution profile over 60 minutes showed a better dissolution (94%) compared with the internationally marketed IPSC capsule (92%).
Interaction of Nitroglycerin with Bovine Serum Albumin and the Influence of Metal Ions on the Binding
Authors: Chengman Bao Chengman Bao , Jialian Wang Jialian Wang , Xuehong Tong Xuehong Tong , Chunli Zhang Chunli Zhang , Xinhui Tang Xinhui Tang
Published: February 2022

The effect of Cu2+, Ca2+, Mg2+and Zn2+ on the interaction between nitroglycerin and bovine serum albumin was investigated. The bimolecular quenching rate constant, the Stern-Volmer quenching constant, the binding constants and the number of binding sites were calculated in the absence and presence of Cu2+, Ca2+, Mg2+and Zn2+. The quenching constants of nitroglycerin to bovine serum albumin were increased in the presence of metal ions. Static quenching mechanism was also confirmed. The binding constants of nitroglycerin to bovine serum albumin were influenced by different metal ions. The enthalpy change, free energy chang, entropy change and the distance between the donor and the acceptor at different temperatures were calculated. The results indicated that energy transfer from bovine serum albumin to nitroglycerin occurs with high probability.
2-Mercaptobenzimidazole Derivatives as Novel Butyrylcholinesterase Inhibitors: Biology-Oriented Drug Synthesis (BIODS), In-Vitro and In-Silico Evaluation
Authors: Muhammad Yousaf Muhammad Yousaf , Momin Khan Momin Khan , Mumtaz Ali Mumtaz Ali , Abdul Wadood Abdul Wadood , Ashfaq Ur Rehman Ashfaq Ur Rehman , Muhammad Saeed Jan Muhammad Saeed Jan , Abdul Sadiq and Faima Alam Abdul Sadiq and Faima Alam
Published: February 2022

Schiff bases gaining remarkable importance day by day in the current situation Schiff bases are found to be a valuable pharmacophore for the synthesis and development of various biologically active heterocyclic compounds. In recent past, we have reported various classes of compounds as enzyme inhibitors, in continuation; A series of 2-Mercaptobenzimidazole hydrazone derivatives (9-42) were synthesized through multistep reactions in high yields and evaluated for butyrylcholinesterase inhibition. In present study, 2-ethylthio benzimidazole was formed by the reaction of 2-Mercaptobenzimidazole with bromoethane. In the second step (2-(2-(ethylthio)benzimidazolyl)acetate) obtained by the reaction of 2-ethylthio benzimidazole with ethyl chloroacetate. In the third step, 2-(2-(ethylthio)benzimidazolyl)acetate was refluxed in methanol with hydrazine hydrate and get 2-((ethylthio)benzimidazolyl)acetohyrazide. In the last step, 2-((ethylthio)benzimidazolyl)acetohyrazide was reacted with different aldehydes in the presence of glacial acetic acid (catalyst) to get a series of 2-Mercaptobenzimidazole hydrazone derivatives. Product was characterized by 1H NMR and 13C NMR.
These newly synthesized compounds showed varying degree of butyrylcholinesterase inhibition. Compound no. 15 with (IC50 = 25.10 and#177; 0.90 and#181;M) was found to be most active in the whole series. Similarly, compounds 42, 12, 40, 17, 22, 28 and 09 exhibited excellent activity with IC50 values are (IC50 = 25.36 and#177; 0.57 and#181;M, IC50 = 27.30 and#177; 0.52 and#181;M, IC50 = 34.31 and#177; 0.59 and#181;M, IC50 = 51.29 and#177; 0.64 and#181;M, IC50 = 54.52 and#177; 0.95 and#181;M, IC50 = 57.90 and#177; 0.45 and#181;M and IC50 = 60.93 and#177;0.67 and#181;M) respectively as compared to standard galantamine 18.13and#177;0.20 and#181;M. Molecular docking helped to find interactions between butyrylcholinesterase enzyme and test compounds.
This study results that Schiff bases have been discovered a new class of butyrylcholinesterase inhibitors which have not been discovered earlier.
Structure, Dielectric Properties and Impedance Spectroscopy of BaTi0.97(Zn,V,Ta)0.03O3 Ceramics
Authors: Raz Muhammad Raz Muhammad , Sajid Ali Sajid Ali , Yaseen Iqbal Yaseen Iqbal , Amir Khesro and Muhammad Uzair Amir Khesro and Muhammad Uzair
Published: February 2022

BaTi0.97Zn0.01V0.01Ta0.01O3and#172; sample was prepared using the conventional mixed oxide sintering route. The samples were characterized using X-ray diffraction, Raman spectroscopy, Scanning Electron Microscopy and Impedance spectroscopy. Structure of the sample was analyzed using Rietveld analysis which showed the formation of tetragonal symmetry. Raman spectroscopy was also in agreement with the XRD results, further indicating the ferroelectric signature in the sample. Electrical microstructure analyzed by impedance spectroscopy analysis revealed two electroactive regions in the sample, belonging to the grain boundary and bulk. An extrinsic conduction mechanism was observed across the sample. Dielectric properties as a function of temperature demonstrated phase transition (TC) at ~ 94 and#176;C, with relative permittivity ~ 3280 at TC. Antiferroelectric-like double hysteresis loops were observed in P-E analysis. The energy storage density was calculated to be 0.26 J/cm3 at an electric field of 50 kV/cm, indicating that BaTi0.97Zn0.01V0.01Ta0.01O3and#172; ceramics can be potentially useful base materials for high density energy storage capacitors.
Molecular Docking Studies on Gingerol Analogues toward Mushroom Tyrosinase
Authors: Sabrina Benouis Sabrina Benouis , Fouad Ferkous Fouad Ferkous , Khairedine Kraim Khairedine Kraim , Ahmed Allali Ahmed Allali , Youcef Saihi Youcef Saihi
Published: February 2022

The gingerol presents the starting point of our work which aims to discover new inhibitors of the tyrosinase enzyme. Therefore, we have studied the activity of gingerol derivatives as inhibitors against mushroom tyrosinase based on the molecular docking.
Molecular docking studies were performed on a series of gingerol analogues retrieved from Zinc database (with 70% as similarity threshold). The gingerol analogues were docked within the active site region of mushroom tyrosinase (PDB: 2Y9X) using Molegro Virtual Docker V.5.0.
The results of molecular docking studies revealed that some analogues of gingerol have higher Moldock score (in terms of negative energy) than gingerol and the experimentally known inhibitors of tyrosinase, and showed favourable molecular interactions exhibiting common molecular interaction with Ala323, Met280 and Asn260 residues of tyrosinase. Furthermore, the top docked compounds used in this work do not violate the Lipinsky rule of five.
Synthesis, Structure and Properties of Two-Dimensional Coordination Polymer Based on 3,5-di(benzimidazol-1-yl)pyridine
Authors: Guo Jun Wu Guo Jun Wu
Published: February 2022

[Cu(L)(AIP)·1.5H2O]n (1) [L= 3,5-di(benzimidazol-1-yl)pyridine, H2AIP= 5-aminoisophthalic acid] was prepared by the solvothermal reaction, which was characterized by single-crystal X–ray diffraction, infrared spectroscopy, and elemental analysis. 1 exhibits an infinite two dimensional [Cu(AIP)]n sheet parallel to (0 1 1) crystal plane. Furthermore, complex 1 displays good photocatalytic degradation of methyl blue (MB).
Antioxidant and Phenolic Characterization with HPLC of Various Extract of Verbascum glomeratum Linneus
Authors: i dem Aydin i dem Aydin , Akgul Rakhimzhanova Akgul Rakhimzhanova , zge Kilin arslan and Ramazan Mammadov zge Kilin arslan and Ramazan Mammadov
Published: February 2022

Verbascum L. species have been used since ancient times in traditional medicine thanks to their bioactive compounds. In this study, we evaluated the antioxidant activity and phenolic contents of ethanolic and acetonic extract of Verbascum glomeratum that collected from Denizli, Turkey. The antioxidant activity were evaluated by using various methods (β-carotene/linoleic acid, ferric reducing power assays (FRAP), radical scavenging assays of 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2and#39;-azino-bis-3-ethyl benzthiazoline-6-sulphonic acid (ABTS), phoshomolibdenum methods) and total phenolic, flavonoid and tannin contents in the extracts were determined. Antioxidant activity was determined as β-carotene/linoleic acid (%58.5and#177;0.021), DPPH (IC50: 1.220and#177;0.025) and ABTS (IC50:1.552and#177;0.021), ferric reducing antioxidant power (FRAP) (4.151and#177;0.056 mgTE/g), phoshomolibdenum assay (8.218and#177;0.015 mgAE/g) total phenolic, total flavonoid and tannin contents was found as (4.41and#177;0.007 mgGAE/mL), (87.142and#177;0.009 and#181;QE/g), and (30.178and#177;0.008 mgCEs/g) respectively, and then 14 different phenolic compounds in ethanol extracts was carried out by HPLC. Epicatechin (2742.09 and#181;g/g) and 2,5dihidroksi (2544.96 and#181;g/g) were the most abundant phenolic constituents in the extracts. According the results, the extract of V. glomeratum may be considered as a potential source of biological agents.
Discrimination of Mungbean Cultivars/Varieties Based on Minor Saccharides Composition by HPLC Coupled with Multivariate Statistical Analysis
Authors: Mudasir Majeed Mudasir Majeed , Abdullah Ijaz Hussain Abdullah Ijaz Hussain , Shahzad Ali Shahid Chatha Shahzad Ali Shahid Chatha , Ghulam Mustafa Kamal and Qasim Ali Ghulam Mustafa Kamal and Qasim Ali
Published: February 2022

Present study reports the potential use of HPLC coupled with principle component analysis (PCA) and partial least squares discriminant analysis (PLSDA), for differentiation of approved mungbean variety from the promising lines based on minor saccharides profiles. A total of 48 mungbean samples from one approved variety and seven promising lines were analyzed for minor saccharides using HPLC and multivariate statistical analysis. PCA showed a clear separation among the classes. PLSDA was conducted to extract the variables that were responsible for the separation of mungbean approved variety from the lines. Maltoheptaose, maltohexaose, maltopentaose, maltotretraose, maltitol, maltose, mannitole, betaine varied significantly while stachyose, raffinose, sucrose, lectitol, dulcitol, xylitol, galactose showed non-significant differences. Maltoheptaose, maltohexaose, maltotretraose, maltitol, mannitole and galactose were found as the most abundant compounds while stachyose, raffinose, sucrose, lectitol and betaine were found less abundant in all lines and approved variety of V. radiata. The study highlights metabolic variation among mungbean variety and lines for minor saccharides profiles and its usefulness for consumers to choose for their desired variety or line as well as for breeders to look into the genetic factors responsible for this variation.
Investigation of the Magnetic and Electronic Properties of Copper Nanocluster Cu14 Contaminated with Fe, Ni and Co
Authors: Maryam Darvishpour Maryam Darvishpour , Mohammad Hossein Fekri Mohammad Hossein Fekri
Published: February 2022

We have presented density functional calculations of the electronic structures and magnetic properties of bimetallics nanoclusters Cu14-nMn (n=1-3) (M=Fe, Ni and Co) in the FCC crystal structure. For the calculations of the physical properties of the compounds, we have used the full potential linearized augmented plane wave method. The magnetic nature, semiconducting, half metallicity and metalloid of transition metals clusters in the FCC crystal structure are investigated. Results show that studied systems have ferromagnetic properties against Cu14Cluster. It is found that band gap of the clusters decreases with doping of atoms compared to pure cluster Cu14, Particularly for Fe. These calculations show that Cu14 and Cu12Co2 are metals, while Cu13Fe, Cu12Fe2, Cu13Co, Cu11Co3 and Cu11Ni3 are half-metals and Cu11Fe3 and Cu12Ni2 are metalloid. Between these clusters, Cu13Ni is semiconductor. The spin polarization and the magnetic moment of the systems are dependent on number and type of the host transition metal atoms. The Cu13Ni has maximum spin polarization and stability. These results provide a new candidate for applications this series of compounds as dilute magnetic clusters and half-metal in spintronic devices.
Application of Modified PANI-ZnO Composites for NH3Gas Sensor at Ambient Temperature
Authors: Naimat Ullah Naimat Ullah , Anwar Ul Haq Ali Shah Anwar Ul Haq Ali Shah , Fazal Akbar Jan Fazal Akbar Jan , Rotaba Ansir Rotaba Ansir , Wali Muhammad Wali Muhammad
Published: February 2022

Polyaniline and zinc oxide nanoparticles were successfully synthesized through inverse emulsion polymerization method and hydrothermal method respectively. For ammonia gas sensing using LCR meter thin film of the composite was fabricated by using spin coater. The functional groups, morphological, optical, structural properties of zinc oxide nanoparticles, polyaniline (emeraldine salt) and composites were investigated by FTIR spectroscopy, Scanning electron microscopy (SEM), UV- Visible spectroscopy and XRD analysis. The formation of ZnO particles of different shapes in the nano range was confirmed from UV-visible and XRD analysis. UV visible spectrum shows the formation of nanoparticles of ZnO. Thin film of Polyaniline/zinc oxide composites were deposited on the surface of copper interdigitated electrode. The fabricated device showed sensitivity to ammonia gas (NH3) at ambient temperature (300 K). It was observed that the resistance is decreases with the increase of volume of ammonia gas. The electrical properties were also investigated of the different concentration of nanocomposite. Optimum sensing response was achieved with PANI in the presence of 50 wt% ZnO nanoparticles. It may also be inferred from this study that the solution mixing process to produce composites has promising future if handled carefully.
Bibliometric Analysis of Adsorption Literatures: Contribution from Pakistan (1991-2017)
Authors: Amtul Qayoom Amtul Qayoom , Ming Huang Wang Ming Huang Wang , Saeeda Nadir Ali and Yuh Shan Ho Saeeda Nadir Ali and Yuh Shan Ho
Published: February 2022

In present work, adsorption related research contribution of Pakistani researchers from 1991 to 2017 have been analyzed by bibliometric methods. In total, 1,737 articles were selected through Science Citation Index Expanded (Web of Science) and statistical analysis of selected publications was conducted on the basis of four indicators such as total number of citations since publication to the end of the recent year, the number of citation of an article in recent year only, the total number of citations for an article in its publication year, and the total number of citations per year. A sharp increase in research output was observed after year 2000 which may be credited to reforms of Higher Education Commission in Pakistan. Though Pakistani researchers produced fewer review papers as compared to original research articles, reviews received three fold more citations. Almost 95% adsorption related articles from Pakistan have been published in low impact factor journals. Multidisciplinary chemistry journals published most of adsorption related Pakistani articles with maximum publications (10%) in Journal of the Chemical Society of Pakistan. Among various research institutes, University of Peshawar, Pakistan ranked first on the basis of total number of articles, first author articles, and corresponding author articles. Six most highly cited publications belonged to Pakistan Council of Scientific and Industrial Research (PCSIR). Number of international collaborative publications increased since 1991 to 2017 and resulted in their ratio being higher as compared to single institutional or nationally collaborative publications. The main focus of adsorption related literature from Pakistan since 1991 to 2017 was removal of metallic or dye contaminants from water and/or industrial effluents.
Neuroprotectıve Potential of the Tubers of Corydalis triternata Zucc. Growing in Turkey
Authors: Mehtap K l c Mehtap K l c , Erdal Kaya Erdal Kaya , Ayhan Ibrahim Aysal Ayhan Ibrahim Aysal , Bilge Sener Bilge Sener
Published: February 2022

The continuing research for the determination of bioactive secondary metabolites from Turkish geophytes as therapeutic agents for dementia is mainly based on the need for drug candidates affected to brain areas. In this study, the in vitro anticholinesterase activity of the alkaloidal fractions of the tubers of Corydalis triternata Zucc. was investigated for their neuroprotective potential. Furthermore, the content of the active alkaloid fractions of the tubers was determined by LC-Q-TOF-MS. The tubers of Corydalis triternata Zucc. were collected from Hatay province of Turkey. The plant species were also preserved as ex-situ in Yalova-Turkey. The alkaloidal extract was prepared from the tubers. The anticholinesterase activities of the extracts and fractions were tested by modification of the Ellman’s method. The optimization of LC-MS conditions was used in ESI in the positive ion mode. The in vitro tests were highlighted that the alkaloidal extract of the tubers exhibited the highest activity against AChE and BuChE with IC50 values of 17.56 and#177; 1.0 g/mL and 326.23 and#177; 2.6 g /mL (galanthamine 6.8 and#177; 0.5 g /mL and 344.4 and#177; 8.2 g /mL as positive control), respectively. The fractions CK-3 and 4 were showed the highest inhibitory activity against AChE with the IC50 value (6.88 and#177; 0.3 g mL and 7.26 and#177; 0.3 g /mL), the fractions CK-5,6,7 and 8 have indicated potent inhibitory activities by compared with galanthamine, which was used as positive control with IC50 value 6.8 and#177; 0.5 g /mL. Among the fractions obtained from the alkaloidal extract, protoberberine-type alkaloids were exerted the most promising activity against both cholinesterases. The present study was described for the first time the in vitro anticholinesterase activity of Corydalis triternata Zucc. as neuroprotective potential and their metabolite profile by LC-Q-TOF-MS. Besides, the anticholinesterase assays on alkaloidal extract and its fractions showed that protoberberine-type alkaloids were determined the most potent inhibitor against AChE and BuChE.
Effect of pH and Dodecylamine Concentration on the Properties of Dodecylamine Two-Phase foam
Authors: Weimin Xie Weimin Xie , Dongsheng He Dongsheng He , Shuang Liu Shuang Liu , Fei Chen Fei Chen , Hongqiang Li Hongqiang Li
Published: February 2022

Over-stabilized foam has always been a problem that plagues the dodecylamine (DDA) flotation system. In this study, a new device, “automatic foam analyzer”, was successfully used to characterize the behavior of foam in DDA solution. The effects of pH and DDA dosage on the foam properties were investigated from four aspects: bubble diffusion capacity, Bikerman coefficient, half-life period and solution conductivity, and the mechanism of pH and DDA concentration on foam properties was analyzed by solution chemistry and surface tension of DDA, then the change process of foam structure was deduced. The results showed that the foaming property and stability of DDA bubbles were the best at pH=8. Simultaneously, with the increase of DDA dosage, the foaming property of bubbles was enhanced, the half-life was prolonged, and the foam stability was also improved.
Synthesis and DFT Studies of Pyrimidin-1(2H)-ylaminofumarate Derivatives
Authors: Murat Saracoglu Murat Saracoglu , Zulbiye Kokbudak Zulbiye Kokbudak , M Izzettin Yilmazer and Fatma Kandemirli M Izzettin Yilmazer and Fatma Kandemirli
Published: February 2022

Pyrimidine derivatives have biological and pharmacological properties. Therefore, in this study we focused on the synthesis various Pyrimidine derivatives to make noteworthy contributions this class of heterocyclic compounds. In the present study, the new compounds (4-6) were obtained by the reactions of 1-amino-5-benzoyl-4-phenylpyrimidin-2(1H)-one (1), 1-amino-5-(4-methylbenzoyl)-4-(4-methylphenyl)pyrimidin-2(1H)-one (2) and 1-amino-5-(4-methoxybenzoyl)-4-(4-methoxyphenyl)pyrimidin-2(1H)-one (3) with dimethyl acetylenedicarboxylate. The structures of these compounds were proved by elemental analysis, FT-IR, 1H and 13C-NMR spectra. In addition to, quantum chemical calculations were made to find molecular properties of the pyrimidin-1(2H)-ylaminofumarate derivatives (4-6) by using DFT/B3LYP method with 6-311++G(2d,2p) basis set. Quantum chemical features such as EHOMO, ELUMO, energy gap, ionization potential, chemical hardness, chemical softness, electronegativity etc. values for gas and solvent phase of neutral molecules were calculated and discussed.
The role of serum D-dimer in the diagnosis of periprosthetic joint infection and timing of reimplantation
Authors: Sahin Erdem , Karaismailoglu Bedri , Ozsahin Mahmut Kursat , Botanlioglu Huseyin , Kaynak Gokhan
Published: February 2022

D-dimer is a fibrin degradation product formed by the destruction of the cross-linked fibrin clot by activation of the coagulation system. Many studies have shown that systemic and local infections cause fibrinolytic activities. The purpose of this study was to determine the role of serum D-dimer in the diagnosis of periprosthetic joint infection (PJI) and the timing of reimplantation. The patients who underwent primary and revision knee or hip arthroplasty between July 2018 and May 2019 were prospectively evaluated. All surgeries were performed by the same surgeon. 60 of 71 patients who met our criteria were included in the study, comprising of 27 primary arthroplasties (PA), 21 two-stage septic revision (SR) and 12 aseptic revision (AR). We analyzed D-dimer, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels. The values of the septic group were evaluated as two groups; Group 1 (before the first stage) and Group 2 (before the second stage) to investigate the role of D-dimer in determining the timing of reimplantation. D-dimer level was significantly higher in the SR group compared to PA and AR groups (p<0.001 and p=0.045). CRP and ESR levels were significantly higher in the SR group compared to PA and AR groups. There was no statistically significant difference between preoperative D-dimer levels of Group 1 and Group 2 (p=0.2). Serum D-dimer level can be used as an easy and inexpensive test to support the diagnosis of PJI. But the D-dimer level is not useful to determine the timing of reimplantation.
Only limited correlations between patient-reported outcomes and objectively monitored physical activity 10-years after THA
Authors: Jelsma Jetse , Van Kuijk Sander , Buil Ivo , Heyligers Ide , Grimm Bernd , Schotanus Martijn
Published: February 2022

In orthopaedics, patient reported outcomes (PROMs) are designed to quantify changes in pain and to assess physical function, most often after joint arthroplasty. However, PROMs have some disadvantages, most important is their subjective nature. The aim was to investigate how patient-self-reported-outcomes of general health, disease-specific outcome and physical function, joint-awareness and self-perceived activity- levels are correlated with objectively-measured physical-activity (PA) parameters derived from wearable activity-monitors (AM) in subjects with a hip-arthroplasty. A prospective cohort study was conducted in a group of 32 patients, with a mean follow-up of 10 years after total hip arthroplasty. To assess different domains, the SF-36 (general health), HOOS-PS (pain/functional outcome), FJS-12 (joint awareness) and SQUASH (physical activity) were chosen. Activity-monitoring was performed using a 3-axis accelerometer, gyroscope and magnetometer. No significant correlations between PA-parameters and the FJS-12 and SQUASH were found. The HOOS- PS was significant correlated with BMI, the daily time walking and total-time active and the amount of daily steps. The physical functioning-subscale of the SF-36 was significant negative correlated with BMI and time sitting, but significant positive correlated with time walking, total-time active and the amount of daily steps. Considering the value of PA for maintaining general health, the value of using sensor-based AMs to assess efficacy of treatments in this health related dimension or use it as a tool for patient education, awareness and communication, seems very high.
Minimally invasive plate osteosynthesis without floating segment fixation for segmental fracture of femur
Authors: Jitprapaikulsarn Surasak , Gromprasit Arthit , Patamamongkonchai Chawanan , Thremthakanpon Witoon
Published: February 2022

Segmental fractures of the femur are technically difficult to manage by intramedullary nailing, the gold standard treatment. We specifically describe minimally invasive plate osteosynthesis (MIPO) without floating segment fixation for this particular fracture pattern. Twenty patients with segmental fractures of the femur were operated on by the MIPO technique. Data were collected on operative time, postoperative complications, union times, and clinical outcomes. The mean operative time was 63.5 minutes (range 50-90). There were no peri-operative complications. All fractures were united with a mean union time of 16.1 weeks (range 12-20). Regarding postoperative malalignment, limb shortening was demonstrated in 4 patients, valgus angulation in 2 and varus angulation in 3. One patient had a bent plate with 7°varus angulation. According to the Thoresen score, 13 were determined to be excellent values, 6 to be good and 1 to be fair. MIPO without floating segment fixation is a safe and effective alternative for segmental fractures of the femur especially in circumstances that are unsuitable or unfeasible for intramedullary nailing.
Ganz osteotomy for treatment of hip dysplasia through intra-pelvic approach. Early results
Authors: Saied Ahmed M , Abouelnas Bassam , El-Adl Wael , Verdonk Rene , Zaghloul Khaled
Published: February 2022

Ganz periacetabular osteotomy (PAO) is a technically demanding surgical procedure. It requires cutting around the acetabulum to mobilize it under fluoro- scopic control. The radiolucent table and good quality imaging are mandatory to perform this osteotomy in a safe way. Modification of Ganz osteotomy was developed a with minimal soft tissue exposure using intra-pelvic approach which allows direct visualization of the quadrilateral plate. The purpose of the present study was to review the early results in the initial group of patients who had this procedure. The Ganz PAO was performed on 8 cases painful dysplastic hips, using the intra-pelvic approach through the Pfannenstiel incision. All of the osteotomies were performed under fluoroscopic control and direct visualizing the osteotomy site from the same incision. The acetabular fragment was medialized and redirected anterolaterally then fixed with 3 screws. The pre-operative Harris hip score mean was 66.8 and improved to be 92.7 (p value <0.0005) and this was statistically significant. Radiologically the CEA improved in the pre-operative X-ray from mean of 13.12 degree to 28.37 degrees (p value <0.0005) and this was statistically significant. Painful dysplastic hips should be treated before function becomes seriously impaired. The Ganz osteotomy through an intra-pelvic approach, can be done with minimal exposure to radiation in a relatively short time.
Superior clinical results and higher satisfaction after customized compared with conventional TKA
Authors: Zeh Alexander , Gehler Valentina , Gutteck Natalia , Beckmann Johannes , Brill Richard , Wohlrab David
Published: February 2022

Investigation of functional outcome and patient`s satisfaction after implantation of a customized versus conventional TKA. In 31 consecutively enrolled patients with primary gonarthrosis, 33 customized TKA (custTKA) and in 31 patients, a conventional TKA (convTKA) was implanted. Perioperative and postoperative management were identical. Radio- graphic evaluation, ROM, KSS (Knee society score) and WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) were performed and patients satisfaction was evaluated after 3 and 12 months. Groups were comparable for age, sex, body mass index and extension/flexion.

After 92 days average flexion in the convTKA group was significantly higher (119 vs. 113 degrees; unpaired t-test). At 375 days, mean flexion in both groups was 120 degrees. There was a significant higher number of outliers of neutral mechanical axis for convTKA patients (11 vs. 3; Chi-squared test). After 92 days there was no difference for KSS (convTKA: 160, custTKA: 167) but significant better results for WOMAC (19 vs. 40) in the custTKA group (unpaired t-test, p= 0.02). In addition, significantly better KSS (181 vs. 156) and WOMAC (99 vs. 42) were found for the custTKA group at 375 days (unpaired t-test, p= 0.002 and 0.001). Patients with the custTKA implant reported significant higher fulfillment of their ex- pectations regarding function and knee strength. In the present study, the patients with a custTKA implant showed significantly superior short-term clinical results and fulfillment of their expectations regarding knee function.