Renal biopsy in diabetic patients (experience of Nephrology Department of Clinic for Internal Diseases UCC Banjaluka)
Authors: Basta Jovanović Gordana , Salapura Aleksandra , Vojvodić Dragan 
Published: July 2014

&lt;p&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.119px; top: 394.957px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.16849);&quot; role=&quot;presentation&quot;&gt;Introduction&lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 214.402px; top: 394.957px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.11335);&quot; role=&quot;presentation&quot;&gt;. Apart from diabetic nephropathy diabetic patients may experience a nondiabetic kidney &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 414.964px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.06783);&quot; role=&quot;presentation&quot;&gt;disease and the kidney biopsy is the best way to diagnose it. The aim of the study is to show the frequency &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 434.964px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.11251);&quot; role=&quot;presentation&quot;&gt;und type of nondiabetic kidney disease diagnosed by kidney biopsy in diabetic patients.&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 464.414px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.15857);&quot; role=&quot;presentation&quot;&gt;Methods&lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 185.694px; top: 464.414px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.1105);&quot; role=&quot;presentation&quot;&gt;. We presented the results of renal biopsy in diabetic patients performed at the Department of &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 484.414px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.09154);&quot; role=&quot;presentation&quot;&gt;Nephrology Clinic for Internal Medicine from April 2007 to May 2013. During the period nine biopsies &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 504.414px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.12858);&quot; role=&quot;presentation&quot;&gt;in diabetic patients were performed (from the total of 157). The biopsy was performed with a biopsy &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 524.413px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.1368);&quot; role=&quot;presentation&quot;&gt;gun- Gun Fast with 16G needle diameter, under control of ultrasound device (Toshiba Famio 5 with&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 544.413px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.10315);&quot; role=&quot;presentation&quot;&gt;probe guide). Two tissue samples were taken: one for optical microscopy and the other for immunoflu&lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 564.413px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.09241);&quot; role=&quot;presentation&quot;&gt;orescence. The mean duration of diabetes was 4.9 years, in two men and seven women. One patient had &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 584.413px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.12583);&quot; role=&quot;presentation&quot;&gt;retinopathy, whereas seven patients had hypertension.&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 613.863px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.15009);&quot; role=&quot;presentation&quot;&gt;Results&lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 174.56px; top: 613.863px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.0997);&quot; role=&quot;presentation&quot;&gt;. The indications for biopsy in our diabetic patients were: six patients with nephrotic syndrome, &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 633.862px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.08362);&quot; role=&quot;presentation&quot;&gt;two with asymptomatic urinary abnormalities (persistent proteinuria and/or microhematuria), one patient &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 653.862px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.1217);&quot; role=&quot;presentation&quot;&gt;with systemic lupus erythematosus. Six patients had a histological diagnosis of diabetic nephropathy, &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 673.862px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.12002);&quot; role=&quot;presentation&quot;&gt;two patients had diabetic nephropathy combined with other disease (one combined with hypertensive&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 693.862px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.14594);&quot; role=&quot;presentation&quot;&gt;nephroangiosclerosis and the other with lupus nephritis), and one patient had primary membranous &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 713.862px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.12085);&quot; role=&quot;presentation&quot;&gt;glomerulonephritis.&lt;/span&gt;&lt;br role=&quot;presentation&quot; /&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 743.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.15026);&quot; role=&quot;presentation&quot;&gt;Conclusion&lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 205.47px; top: 743.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.14154);&quot; role=&quot;presentation&quot;&gt;. Renal biopsy in our nine patients with diabetes showed that three patients (33.3%) had &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 763.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.15765);&quot; role=&quot;presentation&quot;&gt;nondiabetic kidney disease. In total, two out of three patients with nondiabetic kidney disease had &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 783.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.11173);&quot; role=&quot;presentation&quot;&gt;glomerulal disease and one had vascular disease (hypertensive nephroangiosclerosis). Although fewer &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 803.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.10269);&quot; role=&quot;presentation&quot;&gt;patients were considered in comparison to the studies of the other authors, our first experience shows a &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 823.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.08519);&quot; role=&quot;presentation&quot;&gt;significant percentage of diabetic patients with nondiabetic kidney disease, which can only be diagnosed &lt;/span&gt;&lt;span dir=&quot;ltr&quot; style=&quot;left: 118.11px; top: 843.311px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.1154);&quot; role=&quot;presentation&quot;&gt;and confirmed by kidney biopsy.&lt;/span&gt;&lt;/p&gt;