bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Kualitatif Kelengkapan dan Kekonsistensian Diagnosis di Rumah Sakit Patria IKKT
Authors: Suciyanti Suciyanti , Lily Widjaja  , Puteri Fannya  , Dina Sonia
Published: March 2024

Qualitative analysis is a review of filling in medical records related to the consistency of the contents of medical records. A good medical record must contain complete medical records. This type of research is descriptive with a qualitative approach with observation and interview data collection techniques. This qualitative analysis has 6 components. The purpose of this study was to find out a qualitative analysis of the completeness and consistency of diagnosis in dengue fever patients for the period September-October 2022. This research was conducted using a systematic random sampling method. From 85 medical records, the results of a qualitative analysis on the completeness of the consistency of the diagnosis obtained the percentage of consistency of 63.53%. While the results of the 6 subcomponents include: Completeness of diagnosis at admission: 58.82% incomplete, Consistency of diagnosis at admission: 58.82%, Completeness of diagnosis while being treated: 64.71%, Consistency of diagnosis while being treated amounted to: 64.71%, Completeness of diagnosis when going home amounted to: 67.06%, Consistency of diagnosis when going home amounted to: 67.06%. Of the 6 sub-components the highest proportion of consistency was consistency of completeness and consistency of diagnosis at the time of going home = 67.06%. While the lowest completeness & consistency of diagnosis at admission = 58.82%. The conclusion is that the qualitative analysis of the completeness and consistency of the diagnosis is not 100% in accordance with the Hospital MSS.
Hubungan Mutu Pelayanan Kesehatan dengan Tingkat Kepuasan Pasien Rawat Jalan di Poli Umum Puskesmas Kapan Kecamatan Mollo Utara Kabupaten Timor Tengah Selatan
Authors: Sarata Mega Inang Marsalina , Kenjam Yoseph , Yuliana Radja Riwu
Published: March 2024

The quality of health services is an important factor in the utilization of health services. Assessment of the quality of health services is not only on the physical recovery of diseases but also on the knowledge, attitudes, skills of officers when providing health services, communication, information, courtesy, punctuality, responsiveness and availability of adequate physical facilities and environments.  This study aims to analyze the relationship between the quality of health services and the level of outpatient satisfaction at the public poly Kapan Public Health Center, North Mollo District, South Central Timor Regency.  The quality of service analyzed includes the dimensions of physical evidence (tangible), reliability   (reliability), responsiveness (responsiveness), assurance (assurance) and empathy   (empathy).  This type of research is quantitative with an analyticalde science survey using a cross sectional design. The study sample amounted to 94 patients taken using a simple random sampling technique. Data analysis using chi square test  with significance level of 5%. The results showed arelationship between the quality of health services and the level of patient satisfaction based on the dimensions of physical evidence (tangible) p=0.001, dimensions  of reliability (reliability) p=0.008, dimensions of responsiveness p=0.001, dimensions of assurance (assurance) p=0.000 and    dimensions empathy p=0.001 in patients treated at the general poly Kapan Public Health Center, North Mollo District, South Central Timor Regency.
Pengaruh Sistem Informasi Manajemen Terhadap Efektivitas Kerja di Unit Farmasi Rumah Sakit Islam Ibnu Sina Bukittinggi Tahun 2022
Authors: Dessy Angraini  , Ikke Sabrina Putri  , Zulfa Zulfa
Published: March 2024

A good management information system has an influence on the effectiveness of employees' work, including in hospitals. In the pharmacy unit of the Bukittinggi Islamic Hospital, there are several shortcomings in the management information system, such as the input of new drugs that are not directly connected to the management information system at the hospital which causes disruption of waiting times for services at the hospital. The purpose of this study was to determine the effect of management information systems on work effectiveness in the pharmacy unit of the Islamic Hospital Ibnu Sina Bukittinggi. This study uses a cross sectional research method. The study population was all employees in the pharmacy unit of the Islamic Hospital Ibnu Sina Bukittinggi with a sample of 31 people. The sampling technique is total sampling. Data analysis technique is univariate and using structural equation path (smartPLS). The results showed that the t-table value was 1.96 with t-count 0.256, this indicates that t-count t-table means that there is no significant effect of management information systems on work effectiveness in the pharmacy unit of Ibnu Sina Islamic Hospital, Bukittinggi. Based on the r-square, the management information system is only able to affect the work effectiveness of employees by 64.1%, while 35.9% work effectiveness is influenced by other variables.
Faktor-Faktor Yang Berhubungan dengan Kejadian Stunting Pada Balita di Wilayah Kerja Puskesmas Bakunase Kota Kupang
Authors: Hendrika Octavia Nugraheni Kitu  , Yendris Krisno Syamruth  , Sigit Purnawan
Published: March 2024

Stunting or short stature is a term used for children whose height is below average (<-2 SD) of the same sex, chronological age and ideally from the same racial-ethnic group. Stunting can cause children to experience health problems during their growth and development, even irreversible. In the short term, stunting causes a slowdown in the process of growth and development and in the long term it will have an impact on cognitive aspects and the possibility of non-communicable diseases. Therefore, the incidence of stunting is an indicator of child welfare in a country. This study aims to analyze the factors associated with the incidence of stunting in toddlers in the Bakunase Community Health Center, Kupang City. This type of research is an analytical survey, with a case control design. The number of samples was 136 people which were divided into 68 case groups and 68 control groups. The data analysis technique used the chi-square statistical test. The results showed that there was a relationship between mother's knowledge (p value = 0.000, OR = 6.667), mother's attitude (p value = 0.000, OR = 5.808), mother's parenting style (p value = 0.000, OR = 5.093), living environment ( p value = 0.000, OR = 7.538), and the incidence of diarrhea (p value = 0.002, OR = .3.175) with the incidence of stunting in toddlers in the Working Area of the Bakunase Health Center, Kupang City. Therefore, health promotion and cross-sector cooperation are needed to overcome the problem of stunting.
Gambaran Penanganan Status Gizi Balita di Wilayah Kerja Puskesmas Jagir Surabaya
Authors: Jihan Ekanita Anwar  , Akas Yekti Pulih Asih  , Aviana Gita Lara
Published: March 2024

Based on data from the World Health Organization (WHO) in 2017, more than half of the deaths of children under five years are caused by diseases that can be prevented and treated by easy and affordable interventions. The prevalence of wasting under five according to the Indonesian Nutritional Status Survey (2022) in the city of Surabaya is 6.1%. The wasting rate in the city of Surabaya is below the national and provincial averages. Meanwhile, the prevalence of underweight toddlers in the city of Surabaya is 7.5%, this prevalence rate is below the average prevalence of East Java Province, which is 15.8%. Descriptive research with retrospective design, using accidental sampling. In January and February, nutritional status in the normal category had the highest percentages, namely 80.86% and 82.26%. Interventions carried out by health workers resulted in a decrease in the percentage of malnutrition in February by 0.11%. The risk of over nutrition decreased by 1.12%, in nutritional status in the category of overweight and obesity there was also a decrease of 0.04% and 0.37%. Handling programs in reducing malnutrition rates in toddlers, namely monitoring weight and height / body length through home visits, giving milk (CFC), giving KIE to family members, coordinating with cross-sectors if there are obstacles related to non-health problems, there are a decrease in malnutrition status from 4 (0.15%) toddlers in January 2023 to 1 (0.036%) toddlers in February 2023, so that the numbers found are below the minimum target of 1.8% malnutrition rate of the total toddlers examined. The factor of malnutrition is due to congenital abnormalities or what is commonly called a congenital disease.
Pembaruan Rambu Dangerous Goods Area di Terminal Petikemas Nilam
Authors: Wahyu Nur Laili Sutarto  , Abdul Hakkim Zakkiy Fasya
Published: March 2024

There are hazards and risks, especially in the work area of ​​Nilam Terminal Port, which can occur because all activities are carried out every day by workers, passengers, or people around the area, such as loading and unloading of goods, boarding and alighting of passengers, equipment maintenance. , lifting and transporting ship services, as well as other supporting activities, of course require space and also qualified tools/materials to support it. However, apart from that, in utilizing the areas or materials needed, there are concerns and risks that will arise because not all areas or materials are safe, in fact there are so many things that are dangerous, so a warning is needed to serve as an appeal to the workforce. and also the passengers in the area to avoid it. Judging from the research conducted at the Patchouli Container Terminal, warning signs such as dangerous goods have not been implemented in the Port Terminal area so that it can increase the risk of work accidents for workers. So the purpose of this research is to analyze and review related to work safety in the Port Terminal area as well as to develop and recommend innovations in the form of hair renewal of dangerous goods area in the Patchouli Container Terminal. The research was used by discussion and observation methods from 5 August to 23 December 2022 at PT Pelindo Terminal Petikemas. Based on the results of the innovation recommended by the author, it is aimed at paying attention to dangerous areas and objects around the terminal in order to minimize and prevent work accidents for workers. In addition, the main goal is to provide health protection and also Occupational Safety and Health (K3) for workers and companies.
Pengaruh Media Film Pendek tentang SADARI terhadap Pengetahuan dan Sikap pada WUS
Authors: Modesta Yustina Yunita Goang  , Ribka Limbu  , Indriati A. Tedju Hinga
Published: March 2024

Short films are one of the media in health education which has the advantage of being able to convey messages realistically, practically and flexibly. Breast self-examination (BSE) is very important to be used as health education using short films for women of childbearing age. The purpose of this study was to determine the effect of short film media about BSE on the knowledge and attitudes of women of childbearing age (WUS) at KUB Maria Assumpta, Airnona Village, Kupang City. This research is a quantitative research with a quasi-experimental design and uses a pre test-post test with control group design. This research was conducted at KUB Maria Assumpta, Airnona Village, Kupang City with a sample of 36 WUS, using total sampling. The data analysis used was univariate and bivariate analysis using the Paired T-Test statistic. The results showed that short film media had an effect on increasing knowledge and attitudes regarding BSE in WUS at KUB Maria Assumpta, Airnona Village, Kupang City with p value = 0.000 (p˂0.05). Researchers suggest that women of childbearing age learn more about BSE by choosing good health education media so that it is hoped that they can increase knowledge and attitudes about BSE.
Analisis Kualitas Kesehatan Kerja dan Pengaruhnya pada Produktivitas Pengrajin Tenun Ikat Tradisional di Dusun Fopo Kelurahan Onatali Kecamatan Rote Tengah Kabupaten Rote Ndao
Authors: Jois Seselia Atriesta Seme  , Jacob M Ratu  , Soleman Landi
Published: March 2024

The quality of health is closely related to occupational safety and health in the workplace, if the quality of work health is good, the work output will increase. The purpose of this study was to describe the level of quality of health seen from the dimensions of fatigue, muscle complaints, dimensions of occupational diseases in the work life of weavers, to analyze the influence between the dimensions of fatigue and the work productivity of weavers, to analyze the influence between the dimensions of muscle complaints and the work productivity of weavers, to analyze the influence between the dimensions of occupational diseases and the work productivity of weavers. The type of research used is analytic correlation with a quantitative approach and a cross sectional design. The number of samples using total sampling is 60 people. Unibivariate and bivariate data analysis using the chi square test. The results of the bivariate analysis showed that there was a relationship between the dimension of fatigue and work productivity p = 0.007, the dimension of muscle complaints p = 0.000, the dimension of work-related illness p = 0.000. Thus the quality of the health of the weavers is not good, so there is a need for socialization regarding the analysis of the health quality of the weaver workers through direct counseling and through various other media. Weavers are also expected to have awareness to pay more attention to their work patterns so that their health can be maintained properly.
Analisis Postur Kerja Terhadap Keluhan Gangguan Muskuloskeletal pada Pekerja Pemanen Kelapa Sawit
Authors: Rizki Asih Gustara  , Susilawati Susilawati
Published: March 2024

Musculoskeletal diseases (MSDs) are a common complaint because oil palm harvesting is still a manual, labor-intensive and repetitive activity that requires human labour. Due to the non-ergonomic working position, harvesters are prone to musculoskeletal diseases. This study examines the risk factors for musculoskeletal disorders (MSDs) in the agricultural industry using a kind of descriptive analysis and literature review methodology. Five publications were found as a result of a Google Scholar search after a literature search was conducted online at different websites. This research was conducted on 5 publications, all of which were national articles and met the inclusion criteria. To find a solution to a problem, information is evaluated and processed through the steps of organizing, synthesizing, identifying and further analyzing. The findings show that the incidence of musculoskeletal diseases (MSDs) in agricultural workers is influenced by personal factors (age, gender, years of service, medical history, and psychosocial factors), occupational factors (work posture, workload, work duration, repetitive movements and manual materials handling), and environmental factors (work space). Working age is the personal element that is most strongly associated with the occurrence of musculoskeletal diseases (MSDs). Among the workplace and environmental variables that have a substantial correlation with the prevalence of musculoskeletal diseases (MSDs), are work posture and work environment.
Deteksi Mutasi A3243G MTDNA pada Penderita Diabetes Melitus Tipe 2 Menggunakan PCR Alelle’s Specific Amplification (PASA)
Authors: Lestari Windi , Kasmuddin Kasmuddin , Rantisari T A. Meinar Dwi , Saleh Adriandy
Published: March 2024

Type 2 diabetes mellitus is one of the most common metabolic disorders caused by a combination of two men factors: impaired insulin secretion by pancreatic β cells and the inability of insulin-sensitive tissues to respond properly to insulin. The genetically predisposed from of diabetes known as type 2 diabetes mellitus produce the ATP required for the secretory process. An A to G mutation at the 3243-nucleotide position of mitochondrial DNA tRNALeu gene is associated with damage. Maternally Inherited Diabetes and Deafness (MIDD), which was identified as the cause of the mutation, the Allele’s Specific Amplification (PASA) PCR method was chosen because it had not been widely used by other researchers and to increase detection accuracy because the A3243G mtDNA mutation is a heteropblastic mutation. The aim of th research was to detect the A3243G mtDNA mutation in type II diabetes mellitus patiens by using Allele’s Specific Amplification (PASA) PCR. This type of qualitative descriptive research. The result showed the appearance of a 200 bp band in 10 out of 15 samples amplified with D1/DN primer pairs for normal mtDNA and D1/DMt prime pairs.
Faktor Yang Berhubungan Dengan Status Gizi Balita (Bawah Lima Tahun) di Wilayah Kerja Puskesmas Naioni Kota Kupang
Authors: Far Far Gracia Ch. G , Nur Marselinus Laga , Takaeb Afrona E.L
Published: March 2024

Inadequate Nutritional status of Children under five is still a public health issue in Kupang City. The purpose of this study was to analyze factors related to the nutritional status of toddlers (under five years) in the working area of ​​the Naioni Health Center, Kupang City. This study used an analytic observational method with a cross sectional study approach. The total sample of 93 people was selected using the cluster random sampling technique. The results of bivariate analysis using the chi-square test showed that there was a significant relationship between mother's knowledge and toddler nutritional status (p-value=0.024), mother's education (p-value=0.003), family income (p-value=0.005), exclusive breastfeeding (p-value=0.010), and a history of infectious diseases (p-value=0.019). Mother's knowledge is the most related factor to the nutritional status of toddlers. The variable that has no significant relationship is the mother's occupation (p-value = 0.138). Therefore the conclusion of this research is mother’s knowledge, mother’ level of health education, family income, and exclusive breast feeding are variables which have significant relationship with toddles nutritional status while mother’s occupation is a variable which has no relationship with toddler nutritional status in Naioni Health Centre. It is suggested to the health officer to increase health promotion about nutritional status to the community.
Analisis Kualitatif Konsistensi Pencatatan Rekam Medis Rawat Inap Kasus Penyakit Dalam di Rumah Sakit Pelabuhan Jakarta
Authors: Putri Nurindahsari  , Dina Sonia  , Lily Widjaja  , Daniel Happy Putra
Published: March 2024

Qualitative analysis is an activity that examines the filling of medical records for inconsistent and incomplete contents, which indicates that the medical records are inaccurate and incomplete. The purpose of this study was to find out a qualitative analysis of the reliability of recording medical records of inpatient cases of internal medicine for the year 2022. This type of research uses a descriptive method with a quantitative approach and data collection by observation and interviews. Of the 99 medical records, the results obtained were 96% consistent and 4% inconsistent. And the results of the 4 subcomponents include: At the time of admission, namely the consistency of the initial assessment of nurses and inpatient doctors, the results were 98% consistent. On the subcomponent during hospitalization, namely the consistency of progress notes between doctors and nurses, obtaining results of 99% consistency, Consistency of Doctor's Instructions with delivery notes the drug gets 93% consistent results, when going home, namely the consistency of the doctor's return summary and the nurse gets 94% consistency results. Of the 4 sub-components that have the highest consistency, the consistency between the doctor's and nurse's developmental records obtains 99% consistent results. While the lowest was the consistency of the Doctor's Instructions with a record of drug administration obtaining 93% consistent results. The conclusion is that the qualitative analysis of medical record recording is not 100% consistent. It is recommended that the Jakarta Harbor Hospital make standard operating procedures and implement related qualitative analysis of medical records.
Gambaran Faktor-Faktor Penyebab Stunting pada Balita di Wilayah Kerja Puskesmas Sibela Kota Surakarta
Authors: Siti Mutmainah  , Riyani Wulandari
Published: March 2024

Indonesia is the second rank with the highest stunting rate in the Southeast Asia region. Stunting in Central Java reached 20.9%. Meanwhile, Surakarta City is the second highest rank for stunting in Central Java, namely 29.38%. Sibela Health Center is one of the Health Centers with the highest stunting prevalence in Surakarta. Stunting can be caused by maternal factors, toddler factors as well as social, economic, and environmental factors. The purpose of this study was to determine the factors that cause stunting in toddlers at Sibela Health Center in Surakarta City. The method of this study is the Cross- Sectional Survey method collecting data on one population. The results showed that stunting in toddlers at Sibela Health Center in Surakarta city was caused namely energy, and protein on toddlers had not been fulfilled (64.2%), including income under the region's minimum wage (76.9%) and most toddlers are exposed to cigarette smoke (50.7%).
Faktor Risiko yang Berhubungan dengan Perilaku Seksual Pranikah pada Remaja Akhir Usia 20-24 Tahun di Kelurahan Namosain
Authors: Defika Adriana Leonora Ello  , Yuliana Radja Riwu  , Honey Ivon Ndoen
Published: March 2024

Premarital sexual behavior in adolescents is a serious problem in Indonesia. Every year the phenomenon of free sex or premarital sexual behavior by teenagers continues to increase and even adds to the rate of STI transmission and the incidence of HIV/AIDS. The purpose of this study was to determine the risk factors associated with premarital sexual behavior in late adolescents aged 20-24 years in the Namosain Village. This type of research is a quantitative study using a cross sectional research design. The sample size of this study was 340 late adolescents aged 20-24 years in the Namosain village. The results of this study showed that there was no relationship between knowledge and premarital sexual behavior with a p-value = 0.339 > α = 0.05. There is a relationship between sources of information and premarital sexual behavior with a p-value = 0.004 < α = 0.05. There is a relationship between peers and premarital sexual behavior with a p-value = 0.000 < α = 0.05. There is no relationship between parenting style and premarital sexual behavior with a p-value = 1.000 > α = 0.05. There is a relationship between dating style and premarital sexual behavior with a p-value = 0.000 < α = 0.05. Suggestions for parents can apply democratic parenting to children, so they can build good communication with children.
Gambaran Status Kesehatan Masyarakat RT 04 dan RT 07 Dusun Pringgolayan, Kecamatan Banguntapan, Kabupaten Bantul
Authors: Tyas Aisyah Putri  , Aini Zahra  , Asma Karimah  , Reyna Maulidian
Published: March 2024

Health is one of the most important needs in human life. The four main factors that affect the health status of the community are family genetics, environment, individual behavior, and health care facilities. Community diagnosis is important because it can identify broad issues and cover various aspects of the community such as culture, social structure, community roles, and so on. The purpose of this study was to determine the health status of the community at RT 04 and RT 07 in Pringgolayan Hamlet, Banguntapan District, Bantul Regency. This research is a research with a descriptive quantitative design with a purposive sampling method sampling technique with a total of 117 household heads (KK) respondents with data collection through interviews and door-to-door visits. The results of this study revealed that the public health status in RT 04 and RT 07 mostly implemented clean and healthy living behaviors. Conclusion: The public is aware of health behaviors that must be carried out in their daily activities, and health workers are expected to be even more active in conducting health education to the public.
Gambaran Kepatuhan Pasien dengan Penyakit Ginjal Kronis dalam Menjalani Hemodialisis di RSUD Prof.Dr.W.Z. Johanes
Authors: Ishak O. Terru Leo  , Tadeus A.L. Regaletha  , Sigit Purnawan
Published: March 2024

Hemodialysis is a tool that patients with chronic kidney disease (CKD) need to replace damaged kidney function. Compliance with hemodialysis plays an important role in the patient's health condition. Since 2021, the number of hemodialysis patients at RSUD Prof.DR.W.Z. Johanes, from 108 patients to around 85 patients remaining in 2022. This study aims to provide an overview of CKD patients' compliance in undergoing hemodialysis at RSUD Prof.DR.W.Z. John. This type of research is qualitative with a case study approach. Eight key informants and two supporting informants using purposive sampling. The research results showed that generally, hemodialysis compliance among informants was good. Predisposing factors, knowledge about hemodialysis and its risks, motivation to comply with hemodialysis such as the hope of health, not wanting to give up, want to work, and also the desire to still live with the family as well as belief in the benefits of hemodialysis encouraging informants to be more compliant. Supporting factors such as completeness of facilities and affordability of access to services encourage more optimal hemodialysis. Reinforcing factors such as emotional, instrumental, and information support provided by family and health workers increase informants' compliance with hemodialysis. Hemodialysis units can improve and maintain the quality of hemodialysis facilities and services. Existing health workers can increase patient knowledge and motivation by maintaining positive communication during the hemodialysis process. The family can be a positive companion for the fulfillment of hemodialysis patients. Hemodialysis patients must maintain and improve their physical and mental condition.
Faktor yang Berhubungan dengan Status Gizi Anak Balita di Wilayah Kerja Puskesmas Atambua Selatan Kabupaten Belu
Authors: Anna Henny Talahatu  , Jelin Adu  , Afrona E. L Takaeb
Published: March 2024

Nutritional problem in toddlers are still a public helath problem in the South Atambua sub-district, Belu district. The purpose of this study was to analyze factors related to children under five in the working area of the Atambua Selatan Helath Center, Belu Regency. The population in this study were all mothers with toddlers aged 12-59 montsh, totaling 2.126 toddlers. The sample consisted of 219 mothers with random sampling. Data analysis was performed by univariate analysis and bivariate analysis by Chi-Square test. This type of research is aquantitative study using a cross sectional design.  study uses a type of quantitative research with a cross-sectional study design with random sampling techiniques. Respondents in this study were mothers of toddlers, totaling 219 people. The study used univariate and bivariate analysis with the Chi Square test. The results of this study indicate that the variables related to nutritional status are knowledge (0,000), occupation (0,001), education (0,000) and food consumption (0,000). While the variable that is not related to nutritional status is income (0,721). Mother’s nutritional knowledge, mother’s occupation, mother’s education and food consumption have a significant relationship, while family income has no significant relationship with nutritional status. Community Healtg Centers are expected to be able to maximize counseling and counseling activities on a regular basis regarding toddler nutrition and the use of helath promotion media. As well as, the activie role of health workers is urgently needed, especially nutrition and health promotion staff to increase education efforts on the importance of nutritious food for toddlers.
Tingkat Pengetahuan Mahasiswa Prodi Manajemen Informasi Kesehatan tentang Penyakit Malaria
Authors: Bernad Julvian Zebua  , Jetslin Simbolon  , Selviani Damayanti Sipayung
Published: March 2024

Malaria is a disease caused by parasites (protozoa) from the genus Plasmodium which live and reproduce in human red blood cells. This disease is naturally transmitted through the bite of female Anopheles mosquitoes. This study aims to determine the level of student knowledge about malaria in epidemiology courses. This research was conducted at STIKes Santa Elisabeth Medan in October using descriptive research methods. The population used was all level 1 and level 2 health information management study program students at STIKes Santa Elisabeth Medan with a sample size of 15 people. The instruments used were interviews and observations. The form of questionnaire used is a closed questionnaire, where the respondent chooses the correct answer according to the answer chosen in the research questionnaire. The research results showed that students with knowledge understood (73.7%) and did not understand (13.15%) it can be concluded that the level of knowledge of level I and II students of the Health Information Management study program knew about malaria in the epidemiology course, therefore students had to learn and understand and apply malaria prevention in epidemiology courses.
Gambaran Penerapan Sistem Manajemen Keselamatan dan Kesehatan Kerja RSI Ibnu Sina Simpang Empat Tahun 2023
Authors: Mailan Azima  , Meri Herliza  , Dessy Angraini
Published: March 2024

Hospitals are workplaces that have a large workforce with a high risk of occupational disease or work accidents. Based on interviews conducted at RSI Ibnu Sina Simpang Empat and data reports, there were 6 cases of work accidents in 2022. The research aims to find out an overview of the implementation of the occupational safety and health management system at Ibnu Sina Simpang Empat Islamic Hospital in 2023. The research design uses qualitative methods with descriptive approach. The informants in this research were the K3RS committee, nurses and human resources. The research was carried out by means of in-depth interviews, observation and document review. The research results show that the K3 policy has been issued by the hospital director and K3 experts have been consulted. K3RS planning involves identifying the environment in the field and taking considerations. The implementation of the K3RS plan is guided by Minister of Health Regulation No. 52 of 2018. Monitoring and evaluation of K3RS performance is carried out by the K3RS team once every three months. Reviewing and improving K3RS performance is an evaluation carried out twice a year. It is recommended to hospital management that educational delivery is not only verbal but also in writing and on sheets regarding the delivery of the applicable laws.
Faktor-Faktor yang Berhubungan dengan Kejadian Anemia pada Remaja Putri di SMA Negeri 2 Kupang Tengah
Authors: Fitri Sevrilianti Boimau  , Afrona E. L Takaeb  , Maselinus Laga Nur
Published: March 2024

Anemia is a condition in which the number of red blood cells or hemoglobin is less than normal or the level of red blood cells/hemoglobin in the blood decreases. The prevalence rate of anemia in indonesia in 2021 in adolescents is 32%, meaning that 3-4 out of 10 adolescents suffer from anemia. The prevalence rate of anemia in female adolescents at SMA N 2 Kupang Tengah in 2022 is 43 female adolescents. Objective; this study was to determine the factors associated with the incidence of anemia in young women at SMA N 2 Kupang Tengah. The type of research used in this research is an analytic survey with a cross-sectional research design using quantitative research methods. This research began in December 2022-January 2023 at SMA N 2 Kupang Tengah, Kupang Regency. The method used in this research is random sampling. The statistical test used in this study is the Chi-Square. The results showed that the factors associated with anemia in female adolescents at SMA N 2 Kupang Tengah were knowledge level (p=0.000), income level (p=0.000), menstrual cycle (p=0.023), nutritional status (p=0.100). Bivariate analysis showed that there was a relationship between knowledge level, income level, menstrual cycle and nutritional status which had no relationship. It was concluded that the factors associated with the incidence of anemia in SMA N 2 Kupang Tengah were suggested to health workers to increase promotional efforts by conducting socialization or counseling to increase the knowledge of young women.
Dipyridamole cocrystal tablets with enhanced solubility and dissolution at intestinal pH
Authors: NİJHAWAN Monika , DHYAGALA Sadhana , GUNNAM Sailaja , ALETİ Rajeswari , SAXENA Dr Trapti
Published: March 2024

The aim of the study was to prepare dipyridamole(DPM) cocrystals to alter itsphysicochemical properties as it ispoorly soluble in water, 6.8 pHbuffer and belongs to BCS class II. Cocrystals were prepared usingneat grinding method.

Initial screening of cocrystals was done with melting point determination indicating formation of nine cocrystals. Based upon interference studies nine cocrystalswere finalized for solubility and dissolution studies. DPM-citric acid, DPM-hippuric acid, DPM-tartaric acid and DPM-oxalic acid cocrystalsshowed the significant enhancement in solubility and dissolution in 6.8 pH buffer.Further confirmation was done by DSC and PXRD studies. DPM-hippuric acid cocrystalshave shownpromising results for formation of cocrystals and considered for tablet formulation. DPM-hippuric acid cocrystal tablets were prepared by using various levels of carboxymethyl cellulose and microcrystalline cellulose. These tablets showed acceptable physical characteristics with subsequent rapid dissolution.
Development and Evaluation of Pullulan Based Mouth Dissolving Film of Furosemide
Authors: SHAH Aafreen , ATNERİYA Umesh Kumar , JOSHİ Umashankar , SOLANKİ Dharmendra
Published: March 2024

Mouth dissolving oral film is an innovative approach as Oromucosal route for systemic delivery of therapeutically/medicinally active drug substance. As we know Furosemide belongs class IV in BCS classification of drug, having low solubility and permeability due to the presence of strong inter and intramolecular bond. Due to low aqeous solubility, it exhibits low oral bioavailability. Here we are preparing mouth dissolving film of furosemide to increase its solubility, which ultimately will enhance its bioavailability. By this way, we will achieve more rapid drug absorption, desired pharmacological effect with quick onset of action by avoiding degradation in GIT and first pass metabolism. This system will provide maximum therapeutic efficacy and maximum stability by reducing the frequency of dosage and as well as improve patient compliance. The present research aimed to prepare pullulan based mouth dissolving oral films of furosemide used in treatment and control of hypertension. Pullulan was selected as film former exhibit better moisture retention, oxygen barrier and uniform film forming properties. Due to the hydrophilic nature of pullulan, it provides quick dissolution. By considering above points, the film was prepared through solvent casting method by pullulan as film-forming polymer, glycerol as plasticizer and lepidium sativum mucilage as a natural disintegrant known as Asaliyo. Disintegration time, drug release, moisture loss and folding endurance of film were evaluated. Promising batch F6 exhibited better drug dissolution 98.75±0.09% within 8±0.4 minutes than the other films. The disintegration time for batch F6 was 23±5 sec. It is evident from the above results that it is an innovative dosage form to improve the drug delivery, onset of action as well as improve patient compliance.
Investigation of the Effects of Oleuropein on Mouse Detrusor Muscle Contractility
Authors: BARUT Elif Nur , ÖZTÜRK Ahmet Can , ENGİN Seçkin , RENDA Gülin
Published: March 2024

Oleuropein (OLE), Akdeniz bölgesinde yetişen ve birçok biyolojik aktiviteye sahip olan Olea cinsinin en iyi bilinen türü olan Olea europaea L.'den (zeytin) izole edilen önemli bir biyoaktif bileşiktir. Bu çalışmada Olea europaea L.'den izole edlen OLE’nin izole fare detrusor düz kas kontraktilitesine etkisini incelemeyi amaçladık. OLE Olea europaea L'den izole edildi ve in vitro organ banyosu sistemi kullanılarak izole fare detrusor düz kas şeritlerinin kontraktilitesi üzerine OLE’nin etkisi incelendi. Kümülatif OLE’nin (10-8-10-3 M) uygulamasının KCl ile ön-kasılma oluşturulmuş detrusor şeritleri üzerinde gevşetici etkisi araştırıldı. Ayrıca OLE (10-4 ve 10-3 M) inkübasyonunun KCl, karbakol (CCh) ve elektriksel alan stimülasyonu (EAS) ile indüklenen kasılma yanıtları üzerine konsantrasyona-bağımlı etkisi değerlendirildi. KCl ile ön kasılma oluşturulmuş detrusor şeritlerinde OLE, yüksek konsantrasyonda (10-3 M) belirgin gevşeme yanıtına neden oldu. Ayrıca OLE (10-3 M) inkübasyonu KCl, CCh ve EAS ile indüklenen kasılma yanıtlarını anlamlı olarak azalttı (p
Metronidazole Loaded Novel Microemulsion Formulation for Topical Delivery and Characterization With Validated New UPLC Method
Authors: ÇEVİKELLİ Tilbe , GÜVEN Umay Merve , ÖZTÜRK A. Alper
Published: March 2024

The purpose of the study is to develop metronidazole (MET) containing microemulsion systems for topical application, to overcome limitations of local antibacterial treatments. For preparation of drug loaded microemulsions pseudo-phase diagram technique was applied; IPP as oil phase, Span 80 and Cremophor EL as surfactant, ethanol and propylene glycol as co-surfactant and distilled water was used as aqueous phase. Globule size ranging between 126.82.8 to 150.81.6 nm and PDI between 0.210.02 to 0.350.06 were obtained. Zeta potentials of the formulations measured as 0.480.08 – 0.680.14 mV and conductivity was between 0.50.0 and 0.60.0, implicating the formation of w/o emulsions. A UPLC method was developed and validated according to the ICH Q2 (R1) guideline, for quantification of MET, and drug content was calculated as 99.180.08 – 99.330.12%. MET release of 80.620.86% for S1MET and 62.061.08% for S2MET formulations at 24h, indicated the control over the MET release by the microemulsions. After 3. and 6. months, there were no difference in physicochemical properties of microemulsions and MET release showed similar profile; implicating the good stability of formulations.
The Inhibitory Effect of Trimethylamine (TMA), an Intestinal Bacterial Metabolite, on Endothelial Vasorelaxation in Rat Mesenteric Artery
Authors: ÖZKAN Melike Hacer
Published: March 2024

The effect of the gut microbiota metabolite trimethylamine-(TMA) in isolated vessels is unknown yet. Previously TMAO, the hepatic oxidation product of TMA, at 3 mM has been shown to inhibit endothelium-dependent vasorelaxations of isolated arteries only after 24-hour-interactions. In this study, the effects of TMA (at 1 mM) on endothelium-dependent relaxations with acute (1 or 4 hours) and longer (24 hours) incubation periods were evaluated in superior mesenteric arteries of rat. Acute exposure to TMA of 1 hour significantly inhibited acetylcholine-stimulated endothelium-derived hyperpolarizing (EDH) type relaxations, and this inhibition gradually intensified as the incubation period was prolonged to 4, and 24 hours. The area under the curves (AUCs) of the relaxation-response curves after 1 and 24 hours of TMA incubation were found significantly different compared to each other, whereas similar AUC values were obtained after 4, and 24 hours of incubations. Contractile responses to phenylephrine, and nitric oxide (NO)-mediated relaxations of acetylcholine were similar in arteries before and after pretreatment with TMA for 24 hours. These data indicate that TMA selectively inhibits EDH-type relaxations in rat isolated mesenteric arteries. Although the inhibitory effect of TMA intensifies over time, it appears to be more pronounced during acute incubation periods. The findings strengthen the evidence that TMA is a more toxic metabolite on vascular tone than TMAO.
Comparativo da especificidade das escalas de Tinetti e SPPB na avaliação de idosos saudáveis e com disfunções neuromotoras no sul de Goiás
Authors: Carvalho Fernanda Gabriella Lima de , Pin Alessandro dos Santos , Martins Camila Alves , Neto Santos Paula Correa
Published: March 2024

Introdução: o aumento da população idosa no mundo e as alterações fisiológicas decorrentes desse processo refletem a necessidade de boas ferramentas de avaliação para a identificação precoce de possíveis declínios. Objetivo: comparar os achados da avaliação pelas escalas Short Physical Performance Battery (SPPB) e Índice de Equilíbrio e Marcha de Tinetti validadas no Brasil, verificando a especificidade de cada escala na avaliação de idosos saudáveis e com disfunções neuromotoras. Métodos: 76 indivíduos, 43 saudáveis e 33 com disfunção neuromotora, de ambos os sexos, com idade mínima de 60 anos, residentes nos municípios de Caldas Novas-GO, Itumbiara-GO e Goiatuba-GO, foram avaliados em dias alternados pelas escalas SPPB e Tinetti. Resultados: os grupos apresentaram pontuações maiores nas avaliações pelo Índice Tinetti, o que sugere maior sensibilidade da SPPB na avaliação da marcha e do equilíbrio desses indivíduos. Conclusão: SPPB mostrou-se mais específica que o Índice de Tinetti, sendo capaz de detectar alterações que o Índice Tinetti não foi capaz de encontrar.
Properties of pellets made of agglomerated pine and spruce sawdust with theaddition of wheat bran
Authors: Dobrowolska Ewa
Published: March 2024

The effect of the addition of 10%, 15% and 20% wheat bran to pine and spruce sawdust on the kineticstrength, bulk density and specific density of the conglomerate pellet was determined. It turned out that with anincreasing proportion of wheat bran in the sawdust mixture, there was a gradual increase in specific densitycompared to that of pellets agglomerated from wood sawdust alone. At a 20 per cent share of wheat bran, therewas a 7 per cent increase in the kinetic strength of pellets obtained from both types of sawdust. Slight fluctuationsin the bulk density of the pellets occurred with a change in the proportion of wheat bran. The share of wheat branranging from 10% to 20% in the absolutely dry sawdust mixture did not decrease the calorific value. The significantdecrease in calorific value of 13% was mainly due to the increase in moisture content to 12% of the sawdust-wheatbran mixture.
UMA ANÁLISE INTERDISCIPLINAR GEOHISTÓRICA: AS VITRINES SOCIAIS DA BELLE ÉPOQUE NA PRAÇA DOS MÁRTIRES E DA PRAÇA DO FERREIRA EM FORTALEZA, CEARÁ, BRASIL
Authors: Nascimento Marcos Vinícius Vieira do
Published: March 2024

As transformações advindas da Belle Epoque impactaram fortemente o mundo, e essas inúmeras transformações impactaram a capital cearense, Fortaleza, do final do século XIX até a década de 1920. Essas transformações foram sentidas fortemente na economia e na cultura dessa cidade, principalmente nos costumes que eram influenciados pelo modo de vida francês. A Praça dos Mártires e a Praça do Ferreira, ambas localizadas no Centro de Fortaleza, foram os espaços onde essas mudanças ficaram mais perceptíveis, pois eram locais de intensas trocas sociais, servindo de vitrine social e de externalização de hábitos ditos sofisticados. Esse artigo visa entender as principais mudanças que essas transformações, que aconteceram em ambas as praças, causaram na sociedade fortalezense, e com uma abordagem geohistórica, trazer uma reflexão entre passado e presente, compreendendo em sua totalidade como esses espaços estão na atualidade e como essas marcas continuam no cotidiano.
CÂNCER DO COLO DE ÚTERO: CONDUTAS INTERDISCIPLINARES
Authors: Silva William Gomes da , Gomes Larissa Gabriela de Souza , Paiva Mariana Ferreira de Sousa Moreira , Giuliani Carla Denari , Malizia Izabel Cristina Queiroz , Resende Tatiana Carneiro de , Melo Joseane Dias de Lima , Jesus Maristela Rodrigues de
Published: March 2024

O Câncer do Colo do Útero é uma neoplasia maligna, que se localiza no tecido da cérvice uterina, causando alterações celulares de maneira imperceptível. O principal fator de risco  para  o  surgimento  dessa  doença  é  o  contato  com  o Papilomavírus Humano (HPV), que infecta pele, sendo transmitido através das relações sexuais . Os fatores ambientais e genéticos também favorecem o aparecimento do câncer. As ações de prevenção do câncer de colo de útero são de baixo custo e são acessíveis quando se considera a relação custo/benefício; não é necessário o acesso a alta densidade tecnológica.
DESAFIOS ADMINISTRATIVO-ORGANIZACIONAIS NO GERENCIAMENTO SUSTENTÁVEL DE PNEUMÁTICOS INSERVÍVEIS
Authors: Silva Lívia Pereira de Castro da , Santos Gerdana Maria do Nascimento , Cavalcante Bárbara Fernanda Silva Pereira , Arrivabene Liliane da Silva
Published: March 2024

Este artigo aborda os desafios administrativo-organizacionais relacionados à gestão sustentável de pneus inservíveis no Brasil, considerando o aumento da frota de veículos. A Política Nacional de Resíduos Sólidos (PNRS) destaca a necessidade de responsabilidade ambiental na gestão de resíduos, incluindo pneus, e incentiva práticas de reciclagem modernas e logística reversa. A gestão inadequada de pneus descartados apresenta desafios operacionais, econômicos e riscos de sanções legais para as organizações. Estratégias sustentáveis, como ISO 14001 e ESG, são adotadas para integrar práticas sustentáveis nas operações empresariais. Desafios operacionais incluem o processo logístico de coleta e descarte, exigindo parcerias eficazes e gestão eficiente de resíduos. Desafios econômicos envolvem custos de eliminação, transporte e a necessidade de explorar métodos eficazes de reciclagem. Riscos legais podem resultar em sanções e danos à reputação, destacando a importância de cumprir normas ambientais. A Reciclanip, programa da Associação Nacional de Indústrias de Pneumáticos, é referência em logística reversa desde 1999, coletando e destinando pneus inservíveis. No entanto, a política de recolhimento pode variar entre setores e regiões, levando empresas a adotar estratégias próprias. Para enfrentar esses desafios, organizações podem implementar programas internos de recolhimento, estabelecer parcerias com empresas de reciclagem, participar de programas governamentais, oferecer incentivos financeiros e investir em tecnologias para reciclagem e reutilização. Essas práticas não apenas aliviam desafios administrativos, mas também contribuem para a redução dos impactos ambientais. Conclui que a responsabilidade ambiental não é apenas uma obrigação, mas uma oportunidade para as organizações demonstrarem compromisso com a sustentabilidade e construírem uma imagem corporativa positiva.
Desarrollo neurobiológico de la conciencia fonológica y su relación con la lectoescritura
Authors: Andrade-Santamaría Jorge Vladimir , Andrade-Solís Paola Elizabeth , Zumba-Faicán Diana Patricia
Published: March 2024

La lectura y escritura aún requiere aportes para su mejoramiento y es un reto frecuente en la sociedad sobre todo educativa, lo que se hace necesario direccionar la enseñanza desde el cerebro del que aprende. En concordancia con lo señalado, el objetivo principal de esta investigación fue analizar las bases neurobiológicas que intervienen en la conciencia fonológica para el desarrollo de la lectoescritura en estudiantes de educación general básica. Para ello, metodológicamente se utilizó un enfoque de investigación mixta e hibrida, cuyas técnicas de recolección de datos fueron la encuesta a 29 estudiantes, entrevista a 6 padres de familia y a un docente de la Unidad Educativa Angel Polibio Chaves de la ciudad de Guaranda, provincia Bolívar, Ecuador. Una vez obtenido el diagnóstico se elaboró estrategias didácticas que potencian la conciencia fonológica que al aplicarlas revelan que cuando se enriquece el medio en el que se desarrollan los niños y se estimula su cerebro mayor es la conexión y la activación psíquica de los procesos cognitivos y lingüísticos. De ahí que al situar en acción el neuroaprendizaje, es más que suficiente para reducir las dificultades en las habilidades lingüísticas.

Palabras Clave: conciencia fonológica, lectoescritura, desarrollo neurobiológico, estrategias didácticas.