bluuebunny/crossref_metadata_2025 huggingface dataset:
BÜROKRASİDEN SİYASETE TÜRKİYE BÜYÜK MİLLET MECLİSİNİN XIV. BAŞKANI NECMETTİN KARADUMAN
Authors: BULUT Sedef
Published: October 2023

Necmettin Karaduman, Türk siyasetinde iz bırakmış, Trabzon’un yetiştirdiği önemli devlet adamlarından birisidir. 1927 yılında Trabzon’da doğmuş, İlk ve ortaöğrenimini Trabzon’da tamamlamıştır. 1948 yılında Ankara Üniversitesi Siyasal Bilgiler Fakültesi’nden mezun olmuştur. Kaymakamlık ve Mülkiye Müfettişliği, Maraş, Erzurum ve İçel Valiliği görevlerinde bulunmuştur. Bürokrasideki başarılı çalışmalarının ardından bir süre özel sektörde yönetici olarak bulunmuş, 12 Eylül 1980 Müdahalesinin ardından sivil rejime dönüş sürecinde siyasete girmiştir. 6 Kasım 1983 tarihinde yapılan 17. Yasama Dönemi seçimlerinde Anavatan Partisi’nden (ANAP) Trabzon Milletvekili olmuştur. Karaduman, 4 Aralık 1983 ve 12 Eylül 1985 tarihlerinde iki kez olmak üzere Türkiye Büyük Millet Meclisi (TBMM) Başkanlığına seçilerek, 29 Kasım 1987 tarihine kadar bu görevde kalmıştır. Bu makale, Karaduman hakkında bir biyografi çalışması olmayıp TBMM içerisindeki faaliyetlerine odaklanmaktadır. Bu doğrultuda arşiv belgeleri, TBMM Zabıt Cerideleri, süreli yayınlar ve telif ve tetkik eserler yararlanılan başlıca kaynaklardır.
KİTAP DEĞERLENDİRME/BOOK REVIEW Ayhan Yüksel, GİRESUNLU SARIALEMDAROĞULLARI -BİR AİLE TARİHİ-, Serander Yayınları, İstanbul 2022, 384 s., ISBN: 978-605-2104-26-2.
Authors: AKSU KILIÇ Leyla
Published: October 2023

KİTAP DEĞERLENDİRME: Ayhan Yüksel, GİRESUNLU SARIALEMDAROĞULLARI -BİR AİLE TARİHİ-, Serander Yayınları, İstanbul 2022, 384 s., ISBN: 978-605-2104-26-2.
A rare variation of omohyoid and its embryological correlations- A case report
Authors: Chandra Prerna , Mishra Vivek , Sharma Shelja
Published: October 2023

The omohyoid muscle is important in radical neck dissection, as it is a landmark for this operation. Because it divides the anterior and posterior cervical triangles into smaller triangles and its particular relationship to the large cervical vessels, the presence of an anatomical variation of the omohyoid muscle is important. Either belly may be absent or double; and the inferior belly may be attached directly to the clavicle and the superior is sometimes fused with sternohyoid. Variations in the omohyoid muscle might be linked to differences in embryological development, which could influence the muscle’s final form and function. Anderson (Anderson, 1881) theorized that the superior belly of the omohyoid muscle is a true infrahyoid muscle, whereas the inferior belly most likely shares a common embryology with the subclavius muscle. As omohyoid mucle is used to achieve the reconstruction of the laryngeal muscles and bowed vocal folds, the knowledge of the possible anomalies of the omohyoid muscle is important.

In the present study, we have found a case with two inferior bellies & aberrant course of superior belly of omohyoid on right side of 40 years female cadaver embalmed with formalin during routine dissection at Department of Anatomy AIIMS Gorakhpur.

Omohyoid muscle is closely related to large vessels of neck & brachial plexus, so variations in this muscle are clinically important.
A study to assess the effectiveness of awareness program on knowledge regarding management of obesity among house wives in village (Larsun) of district Ganderbal Kashmir
Authors: Manzoor Nusrat , Ul Islam Ishat
Published: October 2023

Obesity often known as “NEW WORLD SYNDROME” is a new disease despite being an old recognized physical feature. Regardless of age or socioeconomic background, obesity is a serious social and psychological condition that affects practically everyone. The threat of invasion affects both developed and growing countries. Similar to how they do in industrialized countries, diet and lifestyle, which are significantly changing as a result of the economic and nutritional transition, have an impact on the risk of obesity. a significant risk factor for the onset of non-communicable diseases as hypertension and heart disease, among others Globally, obesity has reached epidemic levels; at least 2.8 million people die from being overweight or obese each year. Obesity was originally only a problem in high-income nations, but it is now widespread in middle- and low-income nations as well.

The knowledge of housewives in the village of Larsun, district of Ganderbal, regarding obesity was evaluated using a quantitative approach. Data from housewives who met the inclusion criteria were gathered using a purposeful sampling strategy. A self-administered structured knowledge questionnaire was used to obtain the data. 11 professionals validated the tool. By utilizing the Karal-Pearson correlation coefficient (r = 0.83), the tool's dependability was determined. Following the pretest, a structured teaching programme was offered. A posttest was conducted three months later. Quantitative analysis was used to examine the data.

The majority of the subject (12.9%) scored poorly on the pretest, followed by 61.3% who scored well, and 25.8% who scored well. 100% had outstanding knowledge on the posttest. The mean knowledge score before the test was (16.45 +_.943), and the mean knowledge score after the test was (28.45 +_1.12). Additionally, it showed that it had statistical significance (P 0.05).

The funding of the study came to the conclusion that there was a considerable improvement in housewives' understanding of obesity following the implementation of a self-structured instruction programme.
Unsuspected partial hydatidiform moles discovered at laparotomy: A case report
Authors: Merina Hikmah Febty , Rohmah Siti Fatkhiyyatur
Published: October 2023

Gestational trophoblastic disease which develops from placenta and can metastases, involves hydatidiform mole also known as molar pregnancy. It’s extremely rare to have a pregnancy involving hydatidiform mole and a live fetus.

A 30-year-old Javanese woman, gravida 2, para 1, referred to Temanggung Hospital who experienced uterine contractions and vaginal bleeding at 32 weeks’ gestation was considered to have placenta previa. A 2 cm cervical dilation was found during genital exam, along with a cluster of blackish red little grape-like vesicles from her vagina She has never had ultrasound examination. We decide to do emergency cesarean section with their consent. Following spinal anesthesia, the patient experienced an episode of generalized tonic-clonic seizure then she was lost consciousness and needed to be intubated. Later, for mechanical ventilation, she was sent to the ICU. a 950 g, 40 cm long male newborn was delivered with Apgar scores of 6, 6, and 7 respectively at the 1,5, and 10-minute. He was taken right away to the NICU. The placenta which was large and hydropic was recovered manually. Diagnosis was confirmed by histopathology.

Ultrasound is the main method for diagnosing hydatidiform moles. There were just a few changes to the villous vesicles in PHM patients and the majority of pregnancies ended in abortion and fetal death. Despite the extremely low occurrence of the illness, this case is significant since PHM recognition and diagnosis are crucial for patient management. When delivering a live fetus with a hydatidiform mole, a caesarean section is advised because uterine contractions might drive hydatidiform tissue into the abdominal cavity, increasing the risk of pulmonary embolism.

Under careful management, a partial hydatidiform mole and pregnancy can lead to the delivery of a healthy fetus and a live birth.
Construction and Assessment of the Psychometric Characteristics of the Sahm-based Lifestyle Questionnaire
Authors: Esmaeily Masoumeh , Shadabmehr Fahimeh , Dehdast Kowsar
Published: October 2023

Aim: The present research was conducted with the purpose of designing and determining some psychometric characteristics of the Sahm-based lifestyle questionnaire, and this study was done with a practical goal. Methods: The statistical population of the research included all people aged 18 to 60 living in Tehran in 2023, of which 389 people were selected through available sampling and answered the questionnaire. In order to check the validity of the questionnaire, the method of exploratory factor analysis was used, and the content validity of the instrument was confirmed by consulting experts. In order to check the reliability of the tool, Cronbach's alpha method was used. All statistical analyzes were performed by SPSS-25 software. Findings: Based on the findings of the research, exploratory factor analysis with principal components showed that the Sahm-based lifestyle questionnaire is a 13-component tool that explains 57.24 percent of the “Sahmgozari” (partake or sharing) variance. Cronbach's alpha of the whole questionnaire is 0.93 and for components such as meaning-based (0.78), responsibility-based (0.74), agency (0.73), security-based (0.71), principle-based (0.73), respect-based (0.71), intention-based (0.73) , personal peace (0.80), the best role-playing (0.72), formative relationships (0.67), bond-making (0.63), harmonization with goals (0.63), and selectiveness (0.65) were reported. Conclusion: According to the findings, it can be concluded that the Sahm-based lifestyle questionnaire has appropriate and acceptable validity and reliability in the sample of participants in the research.
A Systematic Review of Factors associated with Complicated Grief
Authors: Makvand Zeinab Abbasi , Yousefi Emad , Khajepoor Leyla , Jocar Soheila
Published: October 2023

Aim: This research was conducted with the aim of providing a comprehensive summary of empirical evidence related to complicated bereavement. Methods: This was a qualitative research using systematic review of sources. In this regard, initially, the research literature related to bereavement during the years 2000 to 2021 were examined. The number of 547 articles were identified as related. Finally, according to the entry or inclusion criteria, 42 studies were selected and examined in the final stage. Data were reviewed by two reviewers working independently, and examined using the tool proposed by PRISMA (2009). The reviewers compared the data and discussed disagreements to reach consensus. Consensus data were used in the final analysis. Findings: Finally, data was placed in two groups: Therapeutic factors (encouraging self-regulation, sharing pain with others or restorative retelling, facing or reviewing avoidant situations, reviewing positive memories of the deceased person and inviting negative memories) and risky factors (weakness in mourning rituals, little social support, negative meaning of loss) were placed. Conclusion: Social support is especially important in the treatment of people suffering from complicated grief.
Comparing the Effectiveness of Mindfulness-based Compassion Therapy and Positive Cognitive-Behavioral Therapy on Self-Efficacy of Female-Headed Households
Authors: Rahbarian Azam , Sharifi Tayebeh , Ghazanfari Ahmad
Published: October 2023

Aim: Due to the lack of proper training, female-headed households are suddenly faced with a lot of responsibilities without prior training, as a result of which they suffer stressful conditions and psychological pressure, and finally, the self-efficacy of these females is affected. The purpose of this research was to investigate the effectiveness of mindfulness-based compassion therapy and positive cognitive-behavioral therapy on female-headed households' self-efficacy. Methods: The design of this research was quasi-experimental with pre-test, post-test and three-month follow-up with a control group. The statistical population of research included female-headed households in Shahrekord in the year 2022. In this research, 60 women whose self-efficacy questionnaire score were between 17 and 34 were selected through purposive sampling and were randomly assigned to 2 experimental groups and one control group (20 persons in each group). Then, the experimental groups were treated with eight 120-minute mindfulness-based compassion therapy and positive cognitive-behavioral therapy. The data were collected from the GSE-17 self-efficacy questionnaire, and finally, were analyzed through repeated measure analysis of variance. Findings: The findings showed that in the two stages of post-test and follow-up, the average score of self-efficacy in the two experimental groups was significantly different from the control group. Also, the results of the findings indicated the greater effectiveness of positive cognitive-behavioral therapy. Conclusion: Based on the results of this research, it is suggested to use positive cognitive-behavioral therapy along with other treatment methods to increase the self-efficacy of female-headed households.
A Rare Manifestation of Leptospirosis: Long-Term Elevation in Liver Enzymes
Authors: ÇAKIR Yasemin , GÖKÇE Özlem , TUNCA Bekir
Published: October 2023

Leptospirosis is a bacterial zoonosis that is endemic in many tropical and subtropical regions. The disease is transmitted to humans by contact with the urine or an environment contaminated with the urine of infected animals. The clinical manifestations of leptospirosis vary from subclinical infection to severe illness with multiorgan dysfunction. This case report aimed to present a leptospirosis case diagnosed with detailed anamnesis and progressed with long-term elevation in liver function tests, in a non-endemic region. A 28-year-old male patient was admitted with complaints of weakness, fever, and vomiting. As a result of the detailed anamnesis, it was learned that the patient with hyperbilirubinemia, elevated liver enzymes, and kidney failure had contact with polluted water in a rural area, and the patient was followed up with a preliminary diagnosis of leptospirosis. Leptospirosis may present with different clinical presentations and be confused with many diseases, risk factors should be carefully questioned.
Study of Population Dynamics of Insect-pests in Different Growing Environments and their Relationship with Microclimate of Pigeonpea Cultivars
Authors: Kumar Rajesh , Niwas Ram , Khichar M.L. , Kamboj Mohit , . Kartik
Published: October 2023

Background: Pigeonpea is a low input, rainfed crop that provides economic returns every part of the plant. Insect-pests are the major biotic constraints limiting the productivity of this crop. Keeping all these factors in mind, the present experiment was conducted to study the population dynamics of insect-pests in different growing environments and their relationship with microclimate of pigeonpea cultivars. Methods: A field experiment was conducted at research farm of Department of Agricultural Meteorology, Chaudhary Charan Singh Haryana Agricultural University, Hisar, during Kharif season 2017. Insect-pests population was recorded from the five tagged plants at weekly interval starting from 38th standard meteorological week (SMW) till harvesting of the crop. Ground sheet method was used to record the population of larvae of M. vitrata and H. armigera. Larvae of M. vitrata and H. armigera falling on cloth sheet of size 60 cm × 60 cm laid near plant stem were counted. Web formed by M. vitrata larvae were visually counted and then removed to count larvae feeding inside the webs. Result: In our experiment, it was found that H. armigera infestation started from 38th SMW in all the varieties and D1 and D2 sown crop while in D3 sown crop it started in 40th SMW. On the other hand the larval population of M. vitrata started from 38th SMW, 39th SMW and 40th SMW in all varieties and D1, D2 and D3 sown crops, respectively where as the formation of webs in all the varieties and D1 sown crop started from 38th SMW while in D2 and D3 sown crops started from 39th SMW and continued till 45th SMW. Mean larval population of H. armigera, M. vitrata and number of webs per plant was found highest in D1 sown crop on variety Manak.
Slav Çocukların Okula Uyum Sürecinde Yaşadıkları Sorunlara İlişkin Öğretmen Görüşlerinin İncelenmesi
Authors: ÖZEL Özge , GÜL Mümine
Published: October 2023

Gün geçtikçe dünyada ve ülkemizde göç hareketliği devam etmekte ve birçok ülkedeki göçmen sayısı da sürekli artmaktadır. Türkiye de son yıllarda yoğun göç alan ülkelerden biridir. Ülkedeki göçmen sayısının artması eğitimde çokkültürlülüğün önemini öne çıkarmaktadır. Özellikle okula başlangıç olan okul öncesi dönem göçmen çocukların hem eğitime hem de topluma uyum sağlama basamakları olduğu için çok kritik bir öneme sahiptir. Bu nedenle bu araştırmanın amacı okul öncesi dönemdeki Slav çocukların okula uyum sürecindeki adaptasyon sorunları hakkında öğretmen görüşlerinin incelenmesidir. Araştırma nitel yöntemlerden biri olan durum çalışması olarak düzenlenmiştir. Araştırmanın katılımcıları amaçlı örneklem yöntemlerinden biri olan uygun örneklem yöntemine göre seçilmiştir. Bu kapsamda çalışmanın katılımcılarını Rusya-Ukrayna savaşı nedeniyle en çok göç alan Antalya ili Serik ilçesinde en az bir tane Slav öğrencisi olan 5 okul öncesi öğretmeni oluşturmaktadır. Veriler yarı yapılandırılmış görüşmeler yoluyla toplanmıştır. Araştırma kapsamında toplanan veriler, içerik analizi yöntemi ile analiz edilmiştir. Araştırmada öğretmenlerden elde edilen bulgular, Slav çocukların uyum sürecine ilişkin alınan eğitimler, uyum sürecinde yaşadıkları sorunlar, eğitim sürecinde yaşadıkları sorunlar, diğer öğrencilerle yaşadıkları sorunlar, uyum sürecini kolaylaştırmak için kullanılan yöntemler, eğitim çalışmalarında kullanılan yöntemler ve uyum sürecini kolaylaştırmak için öneriler olmak üzere yedi ana tema altında açıklanmıştır. Sonuç olarak Slav çocukların adaptasyon sürecindeki en büyük sorunlarının dil ve kültür farklılıklarından kaynaklı uyum sorunları olduğu ortaya çıkmıştır. Öğretmenler bu sorunlarla başa çıkmak için akran eğitimi, teknolojik uygulamalar, tercümanlar ve aile işbirliklerine başvurduklarını belirtmiştir. Buna ek olarak çokküültürlü eğitim başta olmak üzere evrensel dil eğitimi ve hızlandırılmış uyum eğitimlerinin gerekliliğini vurgulamışlardır.
Structural and organometric changes of the uterus in conditions of dark deprivation
Authors: Kondakova Larisa I. , Kalashnikova Svetlana A.
Published: October 2023

The effect of 30-day dark deprivation (light-dark cycle 24/0 h, artificial illumination 300 Lux) and 14-day correction with melatonin on the endometrium of the uterus was studied in an experiment on mongrel females of 4 months of age. It was found that 30-day dark deprivation leads to hyperplastic processes of the endometrium: an increase in the number of uterine glands (by 18.9 % p 0.05), thickening of the endometrium (by 12.5 %, p 0.05). Morphometric characteristics of the endometrium: single-layer columnar epithelium of the endometrium and uterine glands were corrected by administration of exogenous melatonin for 14 days.
Influence of local administration of autologous platelet-rich plasma on the level of expression of matrix metalloproteinases in experimental tendinopathy
Authors: Malanin Dmitry A. , Laskov Ilya G. , Ekova Maria R. , Rogova Lyudmila N. , Grigorieva Natalia V. , Povetkina Victoria N. , Demeshchenko Maxim V. , Voronina Anastasia V.
Published: October 2023

Purpose: To evaluate the expression of matrix metalloproteinases in the calcaneal tendon tissue under conditions of experimental tendinopathy and under the influence of local administration of autologous platelet-rich plasma.

Material and methods: The study was conducted on 20 mature Wistar rats divided into 5 groups. In all groups, experimental modeling of tendinopathy of the calcaneal tendon was performed by intra- and near-tendon injection of 0.5 ml of a 10 % suspension of sterile talc. Further, autologous platelet-rich plasma (PRP), hyaluronic acid preparation Rusvisk (Russia) or their sequential combination was injected into the area of tendinopathy. The results of the study were evaluated after 10 weeks; autopsy preparations prepared for immunohistochemical analysis were studied using light microscopy and morphometry.

Results: Histological signs characteristic of tendinopathy were identified: disorganization of collagen structures, mucoid and lipoid degeneration, neovascularization, lymphoid-histiocytic infiltration. Injection of PRP into the area of simulated tendinopathy, hyaluronic acid, or their sequential combination led to changes in the immunohistochemical pattern of the tissue. As a result, there was a decrease in the expression of immunoreactive material in the cytoplasm of tenocytes and cells of the inflammatory infiltrate, compared with the picture observed in micropreparations in animals with tendinopathy, which were not subjected to any manipulations.

Conclusion: The introduction of PRP into the area of the calcaneal tendon under conditions of experimental tendinopathy reduces the level of expression of matrix metalloproteinases and, thereby, preserves the structure of the tendon tissue, demonstrating tendoprotective properties.
Individual variability of the dimensional characteristics of the cervical vertebrae in the applied aspect of developing neurosurgical interventions
Authors: Nikolenko Vladimir N. , Moshkin Andrey S. , Khalilov Maksud A.
Published: October 2023

Modern methods make it possible to study the anatomical structures of the spine with a high degree of detail, which is in demand in neurosurgical practice when planning the most optimal surgical approaches or installing microsurgical stabilizing structures.
Aim: To identify the features of the variability of the size of the cervical spine bodies in the frontal plane during MRI examination.
Materials and methods: 105 magnetic resonance tomograms were studied, in three projections, morphometry of the cervical vertebral bodies and statistical analysis were carried out.
Results and discussion: Among women, the median widths of the C4, C5 vertebrae were the closest, differing by 0.7 mm. The most pronounced differences in the height of the vertebral bodies among men are between C7 and C5, reaching 2 mm.
Conclusion: Differences in the average width of the vertebral bodies of the cervical spine in men and women do not exceed 8 mm. The greatest height differences were for C7 and C5. The data obtained make it possible to improve the methods of computer processing, to improve the methods of personalized treatment of patients when planning endoscopic microsurgical operations and fixing microsurgical stabilizing structures.
Comparative study of methods for the modernization of mesh prostheses as a matrix for the cultivation of fibroblasts
Authors: Ivanov Ilya S. , Ushanov Alexander A. , Mishina Ekaterina S. , Plotnikov Vladislav A. , Bobkova Alexandra R. , Tolkachev Kirill S.
Published: October 2023

Objective: conduct a comparative study of methods for the modernization of mesh prostheses as a matrix for the cultivation of fibroblasts.
Materials and methods: In the experiment conditions, polycaprolactone substance was applied to the surface of mesh hernioendoprostheses according to the original method proposed by V.V. Bereshchenko and a team of co-authors (2019). The polyvinylidene fluoride "Uniflex Standard" prosthesis (Lintex LLC, St. Petersburg, Russia) was chosen as the object of study. After applying the polymer, low-temperature plasma treatment was performed with the characteristics: frequency 5 kHz, pulse voltage 10 kV, power density 2 W/cm2, exposure time 5 minutes. After that, the samples were sterilized using X-ray radiation with a power of 150 kV and an exposure of 3 min. The application of cells was carried out by introducing samples into a DMEM medium with fibroblast culture for 5 days. The obtained samples were studied using scanning electron microscopy. Statistical processing was performed using the nonparametric Mann-Whitney test in the Statistica 10 program (Dell Software Company, Round Rock, Texas, United States of America).
Results: The data obtained indicate the successful attachment of fibroblasts to the surface of modified hernioprostheses.
Emphysematous pyelonephritis and emphysematous cystitis: case report
Authors: Doronin Andrey B. , Zipunnikov Vasily P. , Kuznetsov Alexander A. , Shchelkov Sergey V. , Kapenkin Alexander V.
Published: October 2023

Emphysematous pyelonephritis (EP) is a special form of acute pyelonephritis caused by gas-forming bacteria, leading to necrotic damage to kidney tissue and paranephral fiber. The process is more often one-sided, but about 10 % of the EP cases described in the literature were bilateral in nature. The article describes a clinical case of bilateral emphysematous pyelonephritis in combination with emphysematous cystitis.
Intraoperative prevention of postoperative ammetropies by intrastromal ring implantation
Authors: Izmailova Svetlana B. , Suchkova Valeria A. , Taevere Mariam R. , Zimina Marina V. , Harutyunyan Lana L.
Published: October 2023

The experiment was carried out on 6 isolated donor (cadaver) eyes, penetrating keratoplasty was performed with intrastromal ring implantation according to the proposed method.When modeling the technology we proposed, we obtained patterns identical to those given, we observed a complete cut of the cornea without the formation of tissue bridges and adhesions. The developed new femtosecond laser cutting patterns made it possible to implant the intrastromal ring into the residual corneal stroma of the recipient without the need for additional fixation.
Clinical features of recurrent bronchitis in children with persistent herpes virus infections
Authors: Kasymova Ekaterina B. , Yengibaryan Karine Zh. , Arsanova Khadi I. , Sirotenk Viktor S.
Published: October 2023

A special place is given to the priority areas in pediatrics to improve the basics of medical supervision of patients with recurrent bronchopulmonary pathology, in particular recurrent bronchitis. Among the reasons that often determine the onset of the disease, its subsequent course, and sometimes the outcome, an important role is given to infection, including herpesvirus.
EXPLANATION OF THE MOLECULAR MECHANISM OF ANTI-DEPRESSION THERAPY USING WEBINARS AS LEARNING COMMUNICATION MEDIA
Authors: Agus Adhe Septa Ryant , Khotib Junaidi
Published: October 2023

The Covid-19 Pandemic outbreak has changed various forms of life in society, including restrictions on activities in an open-source environment. The pandemic has also created various kinds of unresolved mental health problems, both in the national dan global area, both those who are directly exposed to the virus and those who are not. Today, the community is still struggling to control the spread of Covid-19, but on the other hand, it has caused the spread of feelings of anxiety, fear and mental pressure due to isolation, physical distancing restrictions, social relations, and other uncertainties. Therefore, these webinar activities were held as one of the online learning communication media, in terms of providing mattery regarding the molecular mechanism of antidepressant therapy, which during the post-Covid-19 pandemic its use increased due to social reasons. This webinar media was very effective without having to gather a crowd and aims to increase knowledge, especially among participants in terms of handling mental health such as depression in terms of its pharmacology therapy. Then, knowing the mechanism of molecular action can improve the optimization of antidepressant therapy according to the patient’s condition. The target participants in this webinar are health workers, students of health study programs, and common people. The webinar activity was conducted by the online system, using the Zoom meeting platform, and was held on April 15th, 2023, then was attended by 241 people, who came from all over Indonesia. From the implementation of the webinar activities, it is known that there has been an increase in understanding of the molecular matter that has been given, this can be seen from the percentage of the correct answers in the post-test evaluation compared to the answers in the pre-test.
INCREASING AWARENESS OF DEPRESSION IN ADOLESCENTS AND CHILDREN THROUGH ONLINE CAMPAIGN ACTIVITIES
Authors: Senjaya Aloysia Ayfen , Hadi Vivia Inayah , Fajrin Hasna Rosyada , Latifah Wahyu Nur , Kencana Cempaka Puspa , Adiningtyas Asri , Tiara Diah Sosialita  , Nawangsari Nur Ainy Fardana
Published: October 2023

Cases of depression in children and adolescents show high rates in Indonesia. According to Riskesdas (2018) adolescents (15–24 years) in Indonesia have a percentage of depression around 6.2% and according to the Yogyakarta branch of Ikatan Dokter Anak Indonesia or Indonesian pediatrician association revealed that 3% of school-aged children and 6% of adolescents experience major depressive disorder. This sizable number comes from the assumption of the public that depression does not occur in children and adolescents. Therefore, the provision of information that increases public knowledge about depression in children and adolescents must be carried out so that both early and curative interventions can be carried out so that in the long run, the prevalence of depression in children and adolescents is reduced. This effort uses two methods 1) disseminating information through Instagram content @semicolonial.id, and 2) digital campaigns via Instagram of each campaign participant. The increase in knowledge of campaign participants (N = 21, Range age = 14–50 years, Mage = 23.5) was measured using  pre-test and post-test. The data processing used a descriptive statistical data analysis through SPSS version 25. The results shows an increase in participants' knowledge before (Range = 40–100, Mean = 71.9) and after (Range = 60–110, Mean = 91.9) the campaign. In conclusion, this campaign was successful in increasing the knowledge of campaign participants about depression in children and adolescents.
OPTIMALIZATION AND SOCIALIZATION OF INTERNET-BASED AQUACULTURE MEDIA CONDITION MONITORING TECHNOLOGY, ARSENIK 2
Authors: Megantoro Prisma , Delfianti Rezi , Putra Prastio Rizki , Nurrohma Hidayah Nayu , Fadhilah Marwan , Rahmad Muzadi Ahmad , Hudzaifah Abdillah Muhammad , Dwi Cahyono Heru , Alauddin Atallah Hafizh , Rafi Nabil Arsalan Muhammad
Published: October 2023

Indonesia's geographical condition, as a maritime country, has a wealth of natural resources in the form of water, which has the potential to support the economy in the aquaculture sector. One of them is the cultivation of freshwater fish ponds as has been carried out by the Maju Rukun Community Group (PokMas) in Ngerong Village, Pasuruan. Lack of equipment and knowledge in monitoring pond water conditions, resulting in problems with the fish nursery process. This is because water is a living medium for aquatic organisms, thus determining the survival of cultivated fish. Therefore, community service activities were held in the form of implementing an appropriate technology device "Arsenik version 2" and a mobile application that can be downloaded on Android to support water quality monitoring in aquaculture. In addition, socialization, training, and seminars regarding parameters of good pond water quality for fish farming were also provided to the Maju Rukun PokMas and the local community. Based on the positive response from the community, the implementation of the Arsenic device version 2 is considered very helpful in terms of monitoring the condition of pond water quality because it has informative parameter values and an easy presentation to understand so that the public can maintain the health of aquatic media for the aquaculture ecosystem in it.
TRAINING AND ESTABLISHMENT OF CODE BULE SYSTEM (EMERGENCY MANAGEMENT) IN ISLAMIC BOARDING SCHOOL DARUL MA’RIFAT GONTOR KEDIRI
Authors: Waloedjo Christrijogo Sumartono , Wirabuana Belindo , Susila Dedi , Sulistiawan Soni Sunarso
Published: October 2023

A heart attack is the sudden cessation of effective heart function in a healthy-looking individual. In general, worldwide morbidity and mortality associated with heart attacks are enormous. This shows the importance of Basic Life Support training for the layman considering the many incidents of cardiac arrest outside the hospital that need a lot of time to get the help of trained health workers The purpose of this social service is to increase knowledge and skills in the field of Basic Life Support, participants are able to practice handling code blue in accordance with the procedures and the flow of fast and precise and carry out Tri-Dharma Higher Education Faculty of Medicine Unair and RSUD Dr.Soetomo. Specific targets to be achieved are the formation of Code Blue System at Pondok Pesantren Putra and the formation of BLS Citizen Community in Kediri. The method used in community service is by In-house training supported by lecture, demonstration and practice methods. The targets of this activity are the students who include 38 students who are given Basic Life Support training for one day, then compared the level of knowledge and attitude before and after (pre post-test design). Different test results obtained p value = 0.352 this value is above 0.05 so that the difference test of attitude before and after training is not different meaningful. However, it does not mean that the training process can be considered unsuccessful in improving the attitude of all participants, because the average attitudes value is still high, more than 4. This is presumably still good attitude retention from Basic Life Support training which has been given in the same population a year ago (December 26, 2016).
IMPROVING STUDENT ACADEMIC RESILIENCE AT SMAN X SURABAYA
Authors: Fikri Hadyan Kusuma  , Cholicul Hadi  , Maria Eko Sulistyowati
Published: October 2023

Increasing academic resilience is very important because resilience is how individual go through challenges and face difficult experiences. Students who have high academic resilience are those who remain motivated for academic achievement and high academic performance even though they are faced with stressful situations and conditions that threaten their performance. The aim of this community service is to increase the academic resilience of SMAN X Surabaya students by providing materials and sharing. The method used to increase the academic resilience of SMAN X students is by providing material and sharing. Students of SMAN X were assessed for their academic resilience before and after giving material and sharing to find out changes in students' academic resilience scores. After pre-test, students were given the material about academic resilience, and at the end of it, students were asked to form a group that’s been determined and with one facilitator in each group that will guide them. In that group students were asked to share their experiences in dealing with challenging situations they’ve been through. Each group then summarize what they’ve learned from the story of every student within the group, after that each group then asked to present what they’ve learned within their group to the class. The participants were 34 students of SMAN X Surabaya. Results of test shows there was an increase in the academic resilience score from the average score before providing material and sharing of 112 to 116. These results mean that providing material and sharing increased the academic resilience of students at SMAN X Surabaya. the students were more likely to seek help, closer to their classmates, and more calm when faced with problem.
Pathogenetic Mechanisms of the Relationship Between Osteoarthritis and Intestinal Dysbiosis
Authors: Poryadin G. V. , Zakhvatov A. N. , Zakharkin I. A. , Parshina A. Yu. , Shaev A. A.
Published: October 2023

The potential association between dysbiosis of the gut microbiota and osteoarthritis is confirming by a growing number of studies. Given the social significance, the high prevalence of osteoarthritis, and evidences that quantitative and qualitative modification of the gut microbiota affects its progression, it seems important to clarify the underlying mechanisms of this association. Osteoarthritis is a multifactorial joint disease, which is based primarily on the progressive degeneration of articular cartilage. Impaired metabolic activity of chondrocytes, consisting in an imbalance in the extracellular matrix synthesis and degradation processes, causes the persistent release of molecular patterns associated with damage. This leads to the activation of a wide range of innate immune cells receptors and is the basis for the development of an inflammatory reaction in the joint. The involvement of macrophages in the synovial membrane and their activation leads to the production of pro-inflammatory cytokines, leading to the development of chronic low-grade inflammation in the joint, supporting the synthesis of catabolic enzymes by chondrocytes and escalating the cartilage degeneration. Microbial dysbiosis, defined as an adverse modification in the diversity, structure, or metabolic activity of the gut microbiota, is a hidden risk factor, accompanied by metabolic endotoxemia and, consequently, by increased production of pro-inflammatory cytokines, that support the systematic low-grade inflammation and pathophysiological mechanisms of osteoarthritis. It has been shown that dysbiosis of the gut microbiota intestinal takes part in the formation of other osteoarthritis risk factors for, for example, obesity and metabolic disorders. The identification of important interrelated pathophysiological mechanisms of these pathologies will contribute to the development of new pathogenetic treatment methods with their subsequent active introduction into clinical practice.
Multidisciplinary Approach to the Management of a Patient with Right-Sided Infective Endocarditis on Maintenance Hemodialysis
Authors: Ponomareva E. Yu. , Kosheleva N. A. , Sedov D. S.
Published: October 2023

Infective endocarditis in patients on maintenance hemodialysis occurs more often than in the population, manifests severe complications and is characterized by high mortality. The management of such patients requires the participation of several specialists. In the presented clinical observation, both typical characteristics of infective endocarditis on maintenance hemodialysis (staphylococcal etiology, association with vascular access devices, metabolic and hemodynamic risk factors) and peculiarities of a particular case (nature of nephropathy that led to maintenance hemodialysis, mechanism of right heart damage, which is uncommon for infective endocarditis on maintenance hemodialysis) are discussed in comparison with literature data. Interdisciplinary interaction of doctors of several specialties contributed to the choice of the right tactics and a favorable outcome of the disease.
Castleman’s Disease. Association with System Scleroderma
Authors: Yagoda A. V. , Koroy P. V. , Kharchenko D. P. , Bondarenko E. V.
Published: October 2023

The article presents an observation of a rare benign lymphoproliferative disease — Castleman’s disease, with pronounced systemic symptoms. The clinical case is of interest not only for the rarity of pathology, but also for the peculiarities of clinical manifestations, including paraneoplastic pseudosclerodermic clinical and immunological syndrome, which was not previously described in the context of Castleman’s disease, Raynaud’s syndrome, severe pulmonary hypertension and a suspected (not proven morphologically) variant of extranodal lesion with its previously also notobserved localization in the sigmoid colon wall.
Format for safe introduction of robotic esophagectomy
Authors: Erodotou Maria , Lagarde Sjoerd M. , Wijnhoven Bas P.L. , van der Sluis Pieter C.
Published: October 2023

The aim of this study is to review the current literature on the learning curve for robotic-assisted minimally invasive esophagectomy (RAMIE) and explore strategies for introducing and implementing RAMIE. A literature search of electronic databases (Pubmed and Science Direct) was conducted using multiple combinations and synonyms of the keywords “esophageal cancer”, “robotic esophagectomy”, “RAMIE”, and “learning curve” up to March 31, 2023. In total, eighteen studies were included. Fourteen studies reported on surgeons with experience in minimally invasive surgery. Seven studies reported on surgeons with prior robotic experience for benign diseases or experience as observant or assistant in robotic surgery or experience on cadaveric robotic training. Four studies reported on a specific training pathway. The learning curve was mostly analyzed using the cumulative sum control chart (CUSUM). The most commonly used measured variables were the total operation time, the thoracic and abdominal console time, the lymph node yield, and vocal cord palsy rates. Τhe learning curve plateaus for the total operative time, the vocal cord palsy rates, and the lymph node yield varied between 20-80, 15-80, and 18-73 cases, respectively. At present, several centers are increasingly adopting RAMIE for esophageal cancer. Education about the learning curve of RAMIE is crucial for the training pathway in order to safely introduce RAMIE in centers without pre-existing robotic esophagectomy experience.
PENERAPAN METODE SAVING MATRIX DALAM PENENTUAN RUTE TERPENDEK PENGANGKUTAN SAMPAH DI KABUPATEN KUBU RAYA
Authors: Muhaimin Ikbal , Yundari Yundari , Pasaribu Meliana
Published: October 2023

The process of transporting waste from the Waste Disposal Site (TPS) to the Final Disposal Site (TPA) is one of the problems in Kubu Raya district that needs attention. This is because the volume of waste in each TPS in Kubu Raya varies, and the number and capacity of transport vehicles provided by the PUPR Office of Kubu Raya is limited. Of course, these problems affect the distance traveled by the transport vehicle, travel time and costs incurred. Therefore, it is necessary to choose the optimal transportation route. The route is said to be optimal when each TPS is transported one way and does not exceed the capacity of the conveyance, so that the total distance obtained is the minimum total distance. The existing problems are then modeled in mathematical form and solved using the Saving Matrix method. This method combines destination points that can be traversed one way by paying attention to the volume of demand for each destination so as not to exceed the vehicle capacity. Based on the research results obtained four optimal vehicle routes with a total distance of 141.6 km. with details for the distance of vehicle route one which is 41.5 km, vehicle route two is 35.95 km, vehicle route three is 35.9 km, and vehicle route four is 28.25 km. This shows that the application of the Saving Matrix method provides more efficient results compared to the previous route of 162 km
UKURAN RISIKO ATAS PERTANGGUNGAN DENGAN BESAR KLAIM YANG TERMODIFIKASI
Authors: Lestia Aprida Siska
Published: October 2023

Coverage modifications results in the amount of payment or reimbursement of claims not being the same as that proposed by the policyholder. Determination of the deductible causes claims below that value to be borne by the policyholder. Meanwhile, setting a policy limit results in a maximum value for claims borne by the insurance company (maximum covered loss). The size of risk as an important value in risk management, which in its determination depends on the distribution of losses in the form of claims, will also be affected by coverage modifications. In this study, risk measure was determined based on the standard deviation and value at risk that using quantile values. In addition, a risk measure is also determined in the form of a conditional tail expectation which is the average value of the loss over a certain quantile and the risk measure is based on a proportional hazard transformation. The size of the risk is determined by the coverage modified by the deductible and policy limit. Apart from that, it is also taken into account that there may be inflation, which of course will also have an impact on the distribution of claims. The observed claim size is known to have a Weibull distribution with certain parameter values, which heavy tailed. The results obtained indicate that modifications in the form of setting deductibles and policy limits have an impact on the magnitude of all risk measures obtained.
SIFAT SUBGRUP NORMAL DARI ANTI SUBGRUP NORMAL FUZZY
Authors: Hira Cendikia , Abdurrahman Saman , Thresye Thresye
Published: October 2023

A fuzzy set is a concept theory that provide a solution of problem that cannot be explained by crisp set. Along with time, research of a fuzzy set are combined with algebra that produce fuzzy algebra. One of the research is a fuzzy subgroup and fuzzy level subset. The other research is an anti fuzzy subgroup that is inspired by a fuzzy subgroup. The purpose of this research is to write further study of anti fuzzy subgroup properties by induction of properties of fuzzy algebra such as fuzzy set, fuzzy subgroup, and anti fuzzy subgroup. The research procedure is to study the basic concept of fuzzy set, fuzzy subgroup, and anti fuzzy subgroup. Using that concept to proof the properties of the anti fuzzy subgroup. The conclusions are in the anti fuzzy subgroup, set  with  anti fuzzy subgroup is a subgroup of a group  that can be applied to complement of  and normal anti fuzzy subgroup closely related to anti fuzzy left coset, right coset, and middle coset.
MODIFIKASI HILL CIPHER DENGAN MENGGUNAKAN MATRIKS KUNCI ORTHOGONAL DAN TRANSPOSITION SUBSTITUTION LEFT RIGHT SHIFT (TSLRS)
Authors: Nugraha Yuniardi Wahyu , Thresye Thresye , Soesanto Oni
Published: October 2023

Matrix is a collection of components arranged in rows and columns, concept of a matrix can be used in solving a problem related to cryptography. A mathematician named Lester Hill created a polyalphabetic cryptographic system called the Hill Cipher. Hill cipher is an algorithm that in its process uses a matrix with size (a × a) as the key matrix. The classic Hill Cipher has the disadvantage that the operation used is not complicated. In this study, the classic Hill Cipher will be modified by using an orthogonal matrix as the key matrix, as well as adding several other operations such as transposition, substitution, and bit shift. This study compares the performance of the traditional Hill Cipher and the modified Hill Cipher in terms of cryptographic techniques on data(text). This research was conducted by encrypting and decrypting the classic Hill Cipher and modified Hill Cipher using similar data (text). Furthermore, a simulation will be carried out using Matlab so that it can use data (text) with a larger size. The results obtained are Hill Cipher which has been modified using an asymmetric cryptographic system, that is in left-right shift process so that the matrix keys will be different when use for encryption and decryption. Because it uses a different key in the encryption and decryption process, thus increasing the level of difficulty in decoding the message.
PERAMALAN JUMLAH PRODUKSI BATUBARAMENGGUNAKAN METODE ARIMA (STUDI KASUS: PT ARUTMIN INDONESIA SITE ASAM-ASAM)
Authors: Simanjuntak Gadys Nauli , Salam Nur , Maisarah Maisarah
Published: October 2023

In the world of industry and investment, the mining sector has an important role in producing natural resources in Indonesia. South Kalimantan Province is one of the regions which is very famous for being rich in natural resources, especially in the mining sector, especially energy minerals in the form of coal. In recent years, coal production at PT. Arutmin Asam Asam experienced an unstable amount of production. This study aims to obtain the best model and predict the amount of coal production at PT Arutmin Indonesia Site Asam-Asam, South Kalimantan Province using the ARIMA (Autoregressive Integrated Moving Average) method. The best Autoregressive Integrated Moving Average (ARIMA) method for predicting coal production at PT Arutmin Indonesia Site Asam-Asam is the ARIMA model (2,1,3) with a smaller Root Mean Square Error (RMSE) compared to other models, namely 92029.74. Forecasting results of coal production at PT Arutmin Arutmin Site Asam-Asam from January to August 2023 tend not to indicate stability or there will be increases and decreases in the forecasting results obtained.