bluuebunny/crossref_metadata_2025 huggingface dataset:
Polarimetry-inspired feature fusion spectroscopy (PIFFS) for ammonia sensing in water
Authors: Fan Axin , Xu Tingfa , Teng Geer , Li Jianan , Zhang Yuhan , Wang Xi , Xu Chang , Yan Peilin , Xu Xin
Published: May 2022

The sustainable use of water resources is inseparable from water pollution detection. The sensing of toxic ammonia nitrogen in water currently requires auxiliary reagents, which may cause secondary pollution. Benefiting from the ability of substances to change light characteristics, this work proposes polarimetry-inspired feature fusion spectroscopy (PIFFS) to detect ammonia. The PIFFS system mainly includes a light source, a quarter-wave plate (QWP), a linear polarizer (LP) and a fiber spectrometer. The target light containing substance information is polarization modulated by adjusting the QWP and LP angles. Then, the Stokes parameters of target light can be calculated by appropriate modulations. The feasibility of PIFFS method to detect ammonia nitrogen is verified by experiments on both standard water samples and environmental water samples. Experimental results show that inspired by the first Stokes parameter, the fused features provide superiority in classifying ammonia concentration. The results also demonstrate the effectiveness of support vector machine-based concentration classification and random forests-based spectral selection. The interaction between light and substances ensures that the proposed PIFFS method has the potential to detect other pollutants.
Design study of a cross-dispersed spatial heterodyne spectrometer: erratum
Authors: Chu Qihang , Li Xiaotian , Jirigalantu  , Sun Ci , Chen Jun , Wang Jianing , Sun Yuqi , Bayanheshig
Published: May 2022

We present an erratum to our article [Opt. Express 30(7), 10547 (2022)10.1364/OE.448504].
Demonstration of 10-channel mode- and polarization-division multiplexed free-space optical transmission with successive interference cancellation DSP
Authors: Li Yiming , Hu Zhouyi , Benton David M. , Ali Abdallah , Patel Mohammed , Ellis Andrew D.
Published: May 2022

We experimentally demonstrate 10-channel mode-division multiplexed free-space optical transmission with five spatial modes, each carrying 19.6925-Gbaud dual-polarization quadrature phase shift keying signals. Strong inter-mode cross talk is observed in our commercially available photonic lantern based system when using a complete orthogonal mode set as independent channels. A successive interference cancellation based multiple-input multiple-output digital signal processing (DSP) algorithm is first applied to mitigate the inter-mode cross talk in mode-division multiplexed systems. The DSP also supports unequal transmit and receive channel numbers to further improve the cross talk resiliency. Compared to the conventional minimum mean square error DSP, the required optical signal-to-noise ratio of the successive interference cancellation DSP is decreased by approximately 5 dB at the hard-decision forward error correction limit. As a result, this system demonstrates a record-high independent channel number of 10 and spectral efficiency of 13.7 b/s/Hz in mode-division multiplexed free-space optical systems.
Secure OFDM transmission scheme based on chaotic encryption and noise-masking key distribution
Authors: Wan Yibin , Ren Jianxin , Liu Bo , Mao Yaya , Chen Shuaidong , Wu Xiangyu , Li Ying , Wu Yongfeng , Zhao Lilong , Sun Tingting , Ullah Rahat
Published: May 2022

In this Letter, we propose a secure orthogonal frequency division multiplexing (OFDM) transmission scheme based on chaotic encryption and noise-masking key distribution. With the implementation of a three-dimensional digital chaotic system, the security performance is effectively enhanced by scrambling the phase, symbol, and subcarrier frequency of the OFDM signal. The proposed noise-masking key distribution can mask the key information of the chaotic system into noise and transmit it with the chaotic encrypted signal simultaneously. By this mechanism, the legal receiver can realize uninterrupted authentication and decryption even if the key is constantly updated. Transmission of a 62.2-Gb/s quadrature phase shift keying (QPSK) and 124.4-Gb/s 16 quadrature amplitude modulation (16QAM) OFDM signal over a 2-km 7-core fiber using the proposed scheme is experimentally demonstrated. The results show that the proposed scheme can realize security enhancement and cost-effective key distribution without significant bit error ratio (BER) performance degradation.
Femtometer-resolved wavelength monitor based on photodiode optoelectronic chromatic dispersion with RF phase-shift amplification
Authors: Liokumovitch Egor , Glasser Ziv , Sternklar Shmuel
Published: May 2022

The spectral sensitivity of photodiode-based optoelectronic chromatic dispersion is enhanced by phase-shift amplification using RF interferometry. With phase-shift amplification of

G
=
4
⋅

10
4

, a peak phase-shift sensitivity of Δθ = 27 deg/pm is achieved, corresponding to a spectral resolution of Δλ
res
 = 1 fm. This all-electronic solid-state technology can serve as an on-chip inexpensive technique for femtometer-resolved wavelength monitoring.
Multi-trait and multi-environment Bayesian analysis to predict the G x E interaction in flood-irrigated rice
Authors: da Silva Júnior Antônio Carlos , Sant’Anna Isabela de Castro , Silva Siqueira Michele Jorge , Cruz Cosme Damião , Azevedo Camila Ferreira , Nascimento Moyses , Soares Plínio César
Published: May 2022

The biggest challenge for the reproduction of flood-irrigated rice is to identify superior genotypes that present development of high-yielding varieties with specific grain qualities, resistance to abiotic and biotic stresses in addition to superior adaptation to the target environment. Thus, the objectives of this study were to propose a multi-trait and multi-environment Bayesian model to estimate genetic parameters for the flood-irrigated rice crop. To this end, twenty-five rice genotypes belonging to the flood-irrigated rice breeding program were evaluated. Grain yield and flowering were evaluated in the agricultural year 2017/2018. The experimental design used in all experiments was a randomized block design with three replications. The Markov Chain Monte Carlo algorithm was used to estimate genetic parameters and genetic values. The flowering is highly heritable by the Bayesian credibility interval: h2 = 0.039–0.80, and 0.02–0.91, environment 1 and 2, respectively. The genetic correlation between traits was significantly different from zero in the two environments (environment 1: -0.80 to 0.74; environment 2: -0.82 to 0.86. The relationship of CVe and CVg higher for flowering in the reduced model (CVg/CVe = 5.83 and 13.98, environments 1 and 2, respectively). For the complete model, this trait presented an estimate of the relative variation index of: CVe = 4.28 and 4.21, environments 1 and 2, respectively. In summary, the multi-trait and multi-environment Bayesian model allowed a reliable estimate of the genetic parameter of flood-irrigated rice. Bayesian analyzes provide robust inference of genetic parameters. Therefore, we recommend this model for genetic evaluation of flood-irrigated rice genotypes, and their generalization, in other crops. Precise estimates of genetic parameters bring new perspectives on the application of Bayesian methods to solve modeling problems in the genetic improvement of flood-irrigated rice.
Virulence and antimicrobial resistance gene profiles of Staphylococcus aureus associated with clinical mastitis in cattle
Authors: Neelam  , Jain V. K. , Singh Mahavir , Joshi Vinay G. , Chhabra Rajesh , Singh Kuldeep , Rana Y. S.
Published: May 2022

Staphylococcus aureus (S. aureus) is the most prevalent microorganism associated with mastitis in cattle, which harbours several virulence factors and antibiotic resistance genes. The present study aimed to characterize S. aureus isolated from mastitic milk of the cattle for antibiotic resistance (blaZ and mecA), haemolysins (hla and hlb) and enterotoxins (sea, seb, sec, and sed) genes. A total of 69 staphylococci were isolated and phenotypically characterized for haemolytic properties on 5% sheep blood agar medium. Out of 69 isolates, 55 (79.71%) were identified as S. aureus by polymerase chain reaction assay. Among S. aureus, the majority of the isolates harboured the gene blaZ (92.73%), followed by coa (89.09%), hlb (60%) and hla (49.09%). Gene mecA responsible for methicillin resistance was detected in 23.64% of S. aureus isolates. Enterotoxin genes seb (9.09%), sec (1.82%) and sed (7.27%) responsible for food poisoning were detected at a comparatively lower rate and none of the S. aureus strain was found positive for sea. Additionally, antimicrobial susceptibility study of S. aureus against 18 antimicrobial discs showed maximum resistance to oxytetracycline, penicillin, and fluoroquinolone groups, contrarily, we observed maximum sensitivity to methicillin and cefuroxime antimicrobials. The high occurrence rate of S. aureus harbouring genes for virulence factors and antimicrobial resistance needs appropriate strategies to control the pathogen spread to the human population.
Pulmonary endothelial cells from different vascular segments exhibit unique recovery from acidification and Na+/H+ exchanger isoform expression
Authors: Adams Dylan , Choi Chung-Sik , Sayner Sarah L.
Published: May 2022

Sodium-hydrogen exchangers (NHEs) tightly regulate intracellular pH (pHi), proliferation, migration and cell volume. Heterogeneity exists between pulmonary endothelial cells derived from different vascular segments, yet the activity and isoform expression of NHEs between these vascular segments has not been fully examined. Utilizing the ammonium-prepulse and recovery from acidification technique in a buffer lacking bicarbonate, pulmonary microvascular and pulmonary artery endothelial cells exhibited unique recovery rates from the acid load dependent upon the concentration of the sodium transport inhibitor, amiloride; further, pulmonary artery endothelial cells required a higher dose of amiloride to inhibit sodium-dependent acid recovery compared to pulmonary microvascular endothelial cells, suggesting a unique complement of NHEs between the different endothelial cell types. While NHE1 has been described in pulmonary endothelial cells, all NHE isoforms have not been accounted for. To address NHE expression in endothelial cells, qPCR was performed. Using a two-gene normalization approach, Sdha and Ywhag were identified for qPCR normalization and analysis of NHE isoforms between pulmonary microvascular and pulmonary artery endothelial cells. NHE1 and NHE8 mRNA were equally expressed between the two cell types, but NHE5 expression was significantly higher in pulmonary microvascular versus pulmonary artery endothelial cells, which was confirmed at the protein level. Thus, pulmonary microvascular and pulmonary artery endothelial cells exhibit unique NHE isoform expression and have a unique response to acid load revealed through recovery from cellular acidification.
Patritumab deruxtecan (HER3-DXd), a novel HER3 directed antibody drug conjugate, exhibits in vitro activity against breast cancer cells expressing HER3 mutations with and without HER2 overexpression
Authors: Koyama Kumiko , Ishikawa Hirokazu , Abe Manabu , Shiose Yoshinobu , Ueno Suguru , Qiu Yang , Nakamaru Kenji , Murakami Masato
Published: May 2022

ErbB3 (HER3), a member of the HER family, is overexpressed in various cancers and plays an important role in cell proliferation and survival. Certain HER3 mutations have also been identified as oncogenic drivers, making them potential therapeutic targets. In the current study, antitumor activity of patritumab deruxtecan (HER3-DXd), a HER3 directed antibody drug conjugate, was evaluated in tumor models with clinically reported HER3 mutations. MDA-MB-231, a HER3-negative human triple-negative breast cancer cell line, was transduced with lentiviral vectors encoding HER3 wild type (HER3WT), one of 11 HER3 mutations, or HER3 empty vector (HER3EV), in the presence/absence of HER2 overexpression. Targeted delivery of HER3-DXd was assessed using cell-surface binding, lysosomal trafficking, and cell-growth inhibition assays. HER3-DXd bound to the surface of HER3WT and mutant cells in a similar, concentration-dependent manner but not to HER3EV. HER3-DXd was translocated to the lysosome, where time- and concentration-dependent signals were observed in the HER3 mutant and HER3WT cells. HER3-DXd inhibited the growth of HER3WT and HER3 mutant cells. HER3-DXd activity was observed in the presence and absence of HER2 overexpression. These data suggest that HER3-DXd may have activity against tumors expressing wild type HER3 or clinically observed HER3 mutations, supporting further clinical evaluation.
Prevalence, trends and associated factors of hypertension and diabetes mellitus in Bangladesh: Evidence from BHDS 2011 and 2017–18
Authors: Sathi Nusrat Jahan , Islam Md. Akhtarul , Ahmed Md. Sabbir , Islam Sheikh Mohammed Shariful
Published: May 2022

The evolving pandemic of non-communicable diseases like hypertension, diabetes mellitus are globally on the rise, and the trend is also escalating in Bangladesh. We aimed to assess the prevalence trend and associated factors of hypertension (HTN), diabetes mellitus (DM), and hypertension- diabetes mellitus combined (HDC) among Bangladeshi adults from 2011 to 2018. Two nationally representative cross-sectional data from Bangladesh Demographic and Health Survey (BDHS): 2011 and 2017–18 were utilized. According to baseline characteristics, the average annual rate of change (AARC) was applied to quantify the annual rate of increase/decrease in HTN, DM, and HDC from 2011 to 2018. The prevalence ratios of HTN, DM, and HDC were assessed through modified Poisson regression with robust error variance (PR, 95% Confidence Interval (CI)). The data were prepared in SPSS version 23 and exported to Stata version 13 for further analysis. Among 11,686 participants, the overall mean age of the study participants was 52.79 years, Standard Deviation (SD)±12.99, and 42.28% were female. From 2011–2018, HTN, DM, and HDC prevalence in Bangladesh has increased by 13, 3.2, and 3.1 percentage points, respectively. The average annual rate of increase was observed in the HTN and HDC prevalence by all socio-economic and demographic categories during 2011–2018. The prevalence of HDC among Chittagong residents was approximately double in 2018: 3.95% (2011) versus 6.59% (2018). Increased age, inactive workers, overweight adults, and adults in wealthy families were common risk factors associated with HTN, DM, and HDC in Bangladesh. The prevalence of developing HTN and HDC was significantly higher among adults aged ≥ 70 years (PR: 2.70, 95% CI: 2.42–3.00; PR: 2.97, 95% CI: 2.08–4.24, respectively). A comprehensive approach of different stakeholders is required to develop appropriate strategies, including appropriate weight management, adequate physical activity, and healthier food habits. Health agencies should take initiatives to spread awareness among people at an early age, but special attention is needed for older people and those at risk for NCDs.
School-going adolescent girls’ preferences and views of family planning services in Phalombe district, Malawi: A descriptive, cross-sectional study
Authors: Chimatiro Chancy Skenard , Mpachika-Mfipa Felistas , Tshotetsi Lumbani , Hajison Precious L.
Published: May 2022

Background

Low uptake of family planning services by adolescent girls remains a public health concern. An estimated 120 out of every 1,000 girls aged 15 to 19 years are having unplanned pregnancies in the sub-Saharan region. Between January and June 2020, the Phalombe District of Malawi reported 3,030 adolescent pregnancies. At this stage, most Malawian schools were closed due to the COVID-19 pandemic. The high rate of adolescent pregnancies prompted the Ministry of Health to provide emergency contraceptives to reduce the number of unplanned pregnancies among adolescents. The provision of emergency contraceptives would be effective if girls were willing and able to access these family planning services. We thus explored the views of school-going adolescent girls regarding their preferences for modern family planning methods including emergency contraceptives in Phalombe, Malawi.

Methods

This was a cross-sectional, descriptive study, where quantitative data were collected using a structured questionnaire. Participants included randomly sampled school-going adolescent girls from eight purposively selected secondary schools and eight randomly selected primary schools. All the schools were sampled from three purposively selected Traditional Authorities namely Nkhulambe, Jenala and Nkhumba which had reported high numbers of adolescent pregnancies. We analyzed the GeoPoints for schools and health facilities using ArcGIS, while adolescent girls’ views were analyzed using STATA.

Results

Participants included 388 adolescent girls, ranging in age from 10 to 19 years (median age = 15.5 years, SD = 1.9 years). Participants were hesitant to use contraceptives because they were afraid of being stigmatized and embarrassed, had to travel long distances to reach the service center, knew little about modern family planning and were afraid of medical complications.

Conclusion

The uptake of family planning services by adolescent girls can be improved by bringing healthcare services closer to schools and homes. Family planning services should employ health workers who are non-judgmental and who are able to remove the stigma associated with family planning. Health workers should at any given opportunity, address the misconceptions and beliefs that adolescents have towards contraceptives. Community sensitization and health talks should be done to improve adolescent girls’ understanding of family planning services.
Association of lipoprotein (a) with coronary artery disease in a South Asian population: A case-control study
Authors: Joseph Jacob , Menon Jaideep Chanayil , Sebastien Placid K. , Sudhakar Abish , John Denny , Menon Geetha R.
Published: May 2022

Introduction

Coronary artery disease (CAD), the leading cause of mortality worldwide, is characterised by an earlier onset and more severe disease in South Asians as compared to Western populations.

Methods

This is an observational study on 928 individuals who attended three tertiary care centres in Kerala, India from 2014-to 2017. The demographic, anthropometric, behavioural factors and the lipoprotein (Lp(a)) and cholesterol values were compared between the two groups and across disease severity. The Chi-square test was used to compare the categorical variables and independent sample t-test for the continuous variables. Multivariable logistic regression was performed to investigate the association of demographic, clinical and behavioural factors with the disease. Odds ratios are presented with a 95% confidence interval. In individuals below 50 years, two logistic regression models were compared to investigate the improvement in modelling the association of the independent factors and Lp(a) with the occurrence of the disease.

Results

We included 682 patients in the diseased group and 246 patients treated for non-coronary conditions in the control group. Those in the control group were significantly younger than in the diseased group(p<0.002). Significantly more patients were diabetic, hypertensive, tobacco users and consumers of alcohol in the diseased group. Multivariable logistic regression on data from all age groups showed that age (OR = 2.55, 95% CI 1.51–4.33, p = 0.01), diabetes (OR = 3.71, 95% CI 2.42–5.70, p = 0.01), hypertension (OR = 3.03, 95% CI 2.12–4.34, p = 0.01) and tobacco use (OR = 5.44, 95% CI 3.39–8.75, p = 0.01) are significantly associated with the disease. Lp(a) (OR = 1.22, 95% CI 0.87–1.72) increased the odds of the disease by 22% but was not statistically significant. In individuals below 50 years, Lp(a) significantly increased the likelihood of CAD (OR = 3.52, 95% CI 1.63–7.57, p = 0.01). Those with diabetes were seven times more likely to be diseased (OR = 7.06, 95% CI 2.59–19.21, p = 0.01) and the tobacco users had six times the likelihood of disease occurrence (OR = 6.38, 95% CI 2.62–15.54, p = 0.01). The median Lp(a) values showed a statistically significant increasing trend with the extent/severity of the disease in those below 50 years.

Conclusion

Age, diabetes, hypertension and tobacco use appear to be associated more with the occurrence of coronary artery disease in adults of all ages. Lipoprotein(a), cholesterol and BMI categories do not seem to be related to disease status in all ages. However, in individuals below 50 years, diabetes, tobacco use and lipoprotein (a) are significantly associated with the occurrence of the disease.
Longitudinal links between behavioral activation coping strategies and depressive symptoms of U.S. adults living alone during the COVID-19 pandemic
Authors: Kim Seoyoun , Yoon Hyunwoo , Morton Patricia , Jang Yuri
Published: May 2022

The COVID-19 pandemic and related physical distancing measures have posed a significant threat to the mental health of adults, particularly those living alone. Accordingly, the World Health Organization implemented the #HealthyAtHome program, encouraging people to keep in regular contact with loved ones, stay physically active, and keep a regular routine. The current study aims to examine a micro-longitudinal link between behavioral activation coping strategies (exercise, meditation, relaxation, and social connection) and depressive symptoms among adults who lived alone during the COVID-19 pandemic. We used 21 biweekly waves of longitudinal data from the Understanding America Study (UAS) collected between April 2020 and February 2021 (N = 1,280). The multilevel models with correlated random effects were estimated to examine lagged effects of coping strategies (t-1) on depressive symptoms (t). The results showed that exercise was predictive of lower depressive symptoms even after controlling for time-invariant and time-varying covariates. The results showed that modifiable lifestyle factors, such as taking time to exercise, may be beneficial for the mental health of Americans living in single-person households.
Effect of ultraviolet C emitted from KrCl excimer lamp with or without bandpass filter to mouse epidermis
Authors: Narita Kouji , Asano Krisana , Yamane Kyosuke , Ohashi Hiroyuki , Igarashi Tatsushi , Nakane Akio
Published: May 2022

It has been reported that 222-nm ultraviolet C (UVC) exerts a germicidal effect on bacteria and viruses as well as UV radiation emitted from a conventional germicidal lamp but is less toxic to the mammalian cells than that from a germicidal lamp. An excimer lamp filled with krypton chloride (KrCl) gas principally emits 222-nm UVC. However, the lamp also emits a wide band of wavelengths other than 222 nm, especially UVC at a longer wavelength than 222 nm and ultraviolet B, which cause DNA damage. There are some reports on the critical role of bandpass filters in reducing the harmful effect of UVC emitted from a KrCl excimer lamp in a human skin model and human subjects. However, the effectiveness of a bandpass filter has not been demonstrated in animal experiments. In the present study, mice were irradiated with UVC emitted from a KrCl excimer lamp with or without a bandpass filter. UVC emitted from an unfiltered KrCl lamp at doses of 50, 150 and 300 mJ/cm2 induced cyclobutyl pyrimidine dimer (CPD)-positive cells, whereas UVC emitted from a filtered lamp did not significantly increase CPD-positive cells in the epidermis. The present study suggested that the bandpass filter serves a critical role in reducing the harmful effect of emission outside of 222 nm to mouse keratinocytes.
Influenza A virus NS1 protein hijacks YAP/TAZ to suppress TLR3-mediated innate immune response
Authors: Zhang Qiong , Zhang Xujun , Lei Xiaobo , Wang Hai , Jiang Jingjing , Wang Yuchong , Bi Kefan , Diao Hongyan
Published: May 2022

The Hippo signaling pathway, which is historically considered as a dominator of organ development and homeostasis has recently been implicated as an immune regulator. However, its role in host defense against influenza A virus (IAV) has not been widely investigated. Here, we found that IAV could activate the Hippo effectors Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) through physical binding of the IAV non-structural protein 1 (NS1) with C-terminal domain of YAP/TAZ, facilitating their nuclear location. Meanwhile, YAP/TAZ downregulated the expression of pro-inflammatory and anti-viral cytokines against IAV infection, therefore benefiting virus replication and host cell apoptosis. A mouse model of IAV infection further demonstrated Yap deficiency protected mice against IAV infection, relieving lung injury. Mechanistically, YAP/TAZ blocked anti-viral innate immune signaling via downregulation of Toll-like receptor 3 (TLR3) expression. YAP directly bound to the putative TEADs binding site on the promoter region of TLR3. The elimination of acetylated histone H3 occupancy in the TLR3 promoter resulted in its transcriptional silence. Moreover, treatment of Trichostatin A, a histone deacetylases (HDACs) inhibitor or disruption of HDAC4/6 reversed the inhibition of TLR3 expression by YAP/TAZ, suggesting HDAC4/6 mediated the suppression function of YAP/TAZ. Taken together, we uncovered a novel immunomodulatory mechanism employed by IAV, where YAP/TAZ antagonize TLR3-mediated innate immunity.
Bizkaiko euskararen barne-egituraketaz: sartaldea eta sortaldea
Authors: Zuloaga Eneko
Published: May 2022

Lan honetan Bizkaiko euskara dut aztergai; zehazki, Bizkaiko mendebala eta ekialdea bereizteko balio dezaketen lau ezaugarri aurkezten ditut. Orain arte ez da gaiari buruzko monografiko sakonik egin, eta lan honek hurbilketa izan nahi du. Izan ere, denok darabilgu gogoan banaketa hori, eta uste dut merezi duela zenbait ikuspegi eta ideia aztertzea eta zehaztea. Horretarako, aurretik egindako lan apurrak eta nik neuk lan honetarako baztertutako ezaugarriak aurkeztu ondoren, baliagarritzat jotako laurak aztertu ditut; zehazki, (-o + -a > ua erdiko bokala igotzea, soziatiboko markak, hurbiltze-adlatiboaren markaren aldaerak eta *edun aditzaren 3. pertsona pluraletan -de pluralgilearen -de & -e aldaerak. Ezaugarri bakoitzak egun duen hedadura mugatu ondoren, azken mendeotako bilakabidea aztertu dut testu arkaiko, zahar eta klasikoak oinarri hartuta. Horrek, gainera, bidea eman dit ezaugarri horien eta Bizkaiko euskararen historia hobeto ezagutzeko, eta ikuspegi teorikoari eta erabaki metodologikoei buruz zenbait hausnarketa egiteko.
Euskal lexiko etnometeorologikoaren azterketa: kultura eta kognizioa
Authors: Dieguez Kepa
Published: May 2022

“Euskal lexiko etnometeorologikoaren azterketa” deritzon tesiaren laburpen moldatua da artikulu hau. Horretarako, azaltzen da zein testuinguru teorikotan kokatzen den eta zein jakintzaz baliatzen den; ondoren, metodologia etnolinguistikoaren berri ematen da, datuak sailkatu, interpretatu eta azaltzeko. Behin hori eginda, fenomeno atmosferiko nagusien lexikoaren azterketaren emaitza behinenak adierazten dira, eta, azkenik, lexiko guztia aintzat harturik, ondorio nagusien berri ematen da.
Vinsonen eta van Eysen arteko gutunak
Authors: Munduate Ugartemendia Manex
Published: May 2022

Lan honen helburua XIX. mendeko bi euskalariren arteko gutunak arakatuz horien edizioa osatzea da, garai hartako euskalaritza eta hizkuntza-ideien inguruan gutxi gorabeherako ikuspegi bat eduki ahal izateko. Hautatu dudan gutun-sorta 1868tik 1901era Julien Vinsonek eta Willem Jan van Eysek elkartrukatutako ehun eta hiru gutunek osatzen dute.
Oro har, Vinsonen hizkuntzalaritza ikuspegiak van Eysenarekin bat egiten du, besteak beste euskoiberismoaren auziari eta euskal gramatikaren eta aditz ereduaren orokortasunei dagokienez. Alabaina, badira euren artean eztabaida sortzen duten gai zehatzagoak ere.
Gainera, gutunetan batez ere Vinsonek garaiko hizkuntzalari nahiz euskalariekin izandako aurrez aurrekoak ere azaleratzen dira.
Amaitzeko, ezin alde batera utzi batak zein besteak euskal testu zaharren bilketa eta edizioan eginiko lanak. Gutunetan zehar aipamen ugari jasotzen dituzte edizioen bilketa eta prestaketa lanek.
Evaluación de la intervención en paciente diabético en la farmacia comunitaria (zona urbana en Valladolid durante el periodo de abril a junio del 2021)
Authors: Valles Martín Elena , Mateos Rodríguez Elena , Treceño Lobato Carlos , Melgar Vicente María José
Published: May 2022

La diabetes mellitus es una enfermedad crónica que presenta una prevalencia en la población española del 6,8?%, siendo el 96,6?% diabetes mellitus tipo II.

Tomando como un gran problema de salud esta enfermedad, el objetivo de este estudio es la búsqueda proactiva desde la oficina de farmacia de los problemas relacionados con la medicación o resultados negativos de los medicamentos con la finalidad de poder resolverlos y mejorar su calidad de vida.

En una primera fase, se hizo el cribado de inclusión de pacientes al estudio y, posteriormente, se realizaron encuestas a los mismos para la recogida de información necesaria para el trabajo.

Gracias a los resultados que obtuvimos, pudimos ver que muchos pacientes tenían PRM y RNM que podían ser subsanables si eran detectados, como, por ejemplo, problemas de salud insuficientemente tratados, interacción potencial o probabilidad de efectos adversos. Además, el paciente tratado con monoterapia de metformina tenía mayor probabilidad de sufrir reacciones adversas o PRM derivados del medicamento.

Con todo ello, la intervención del farmacéutico en la detención y resolución de estos problemas conlleva la mejora de la calidad de vida del paciente diabético.
Continuing Medical Education Questions: May 2022
Authors: Inamdar Sumant
Published: May 2022

Article Title: Evolutionary medicine perspectives: Helicobacter pylori lactose intolerance, and three hypotheses for functional and inflammatory gastrointestinal and hepatobiliary disorders
Continuing Medical Education Questions: May 2022
Authors: Dulaney David T.
Published: May 2022

Article Title: Irritable bowel syndrome and long-term risk of cancer: a prospective cohort study among 0.5 million adults in UK Biobank.
Mapas de comunicaciones de Barranquilla. Primera mitad de siglo XX
Authors: Vidal Ortega Antonino , Uribe Marenco Marlem
Published: May 2022

Planos de rutas aéreas y ferroviarias, entre otras de Colombia elaboradas por Karl Parrish.
Indios y españoles en la antigua provincia de Santa Marta, Colombia Documentos de los siglos XVI y XVII.
Authors: D'Amato Castillo Guissepe
Published: May 2022

Reseña del libro "Indios y españoles en la antigua provincia de Santa Marta, Colombia Documentos de los siglos XVI y XVII" del autor Karl Langebaek
De rebeldes a sediciosos. Cultura política en la nueva granada en la primera mitad del siglo X
Authors: Monsalvo Mendoza Edwin , Conde Calderón Jorge
Published: May 2022

Este artículo analiza la transición del gobierno desde la disolución de Colombia y los primeros años de la Nueva Granada a partir de los discursos que las facciones santanderistas y bolivarianas crearon para señalar a sus contrincantes políticos. Creando así un ambiente de sospecha en el que pulularon las acusaciones de rebeldía o sedición como arma política para justificar la expulsión o el fusilamiento de los adversarios. La fuente que utilizamos son procesos judiciales contra conspiradores y sediciosos. La hipótesis que aquí sostenemos es que esta estrategia permitió que la facción que se encontrara en el gobierno se apoderara de los cargos públicos y a los que estaban por fuera de éste, como una medida de coacción al gobierno al mantener viva la amenaza de una supuesta guerra racial.
Dinámicas del poblamiento en el caribe continental colombiano (1938-2005)
Authors: Avella Francisco , Mahecha Nathaly
Published: May 2022

El espacio regional del Caribe continental colombiano está organizado de acuerdo al difícil poblamiento de lo que desde la colonia tradicionalmente se han llamado "zonas no aptas para el poblamiento". Estas zonas están caracterizadas por ser demasiado bajas, inundables, calurosas, de prolongadas sequías, y con períodos de intensas lluvias que no permiten una humedad relativa del suelo aceptable a lo largo de todo el año, por lo que no son aptas para la agricultura, según diversos analistas. Este espacio ha sido ocupado por una población que se ha movido entre la esperanza de tener tierras y la frustración de perderlas. Lo que ha producido una dinámica poblacional, que el estudio capta a partir de los saldos de efecto migratorio (SEM e ISEM) en municipios agrupados en comarcas, como los estudiaron Guhl y Fornaguera, en cada uno de los Censos entre 1938 y 1964. El objeto de este análisis es el de buscar relaciones entre los procesos migratorios de "resto" (área rural) y "cabecera" (área urbana), comparando los períodos intercensales, para formular posibles explicaciones sobre la asociación que los episodios violentos tienen con estos procesos migratorios y como se reflejan en la organización espacial del dichos territorios. Los resultados muestran patrones cíclicos en el área rural inversamente complementarios a los procesos violentos, que en unos períodos intercensales expulsan y en los más recientes atraen población. Lo que solo se puede entender a partir del contexto particular del conflicto en cada una de las comarcas, pues la suma de lo que sucede en las comarcas, no es igual al resultado de toda la región. Por el contrario su comportamiento es diferente.
Diligencias de secuestros practicadas en 1820 por las autoridades republicanas de Mompós en contra de los españoles opuestos a la causa patriota
Authors: Pita Pico Roger
Published: May 2022

El documento que se transcribe a continuación revela los detalles del proceso de secuestro de las casas y bienes muebles pertenecientes a los desafectos españoles residentes en la localidad de Mompós a mediados del año 1820. Abandono, desolación y estancamiento económico es lo que se observa en las descripciones de los activos incautados, lo cual es reflejo de la represión aplicada por el gobierno republicano después de haber recuperado definitivamente esta zona de la Costa Caribe.
Retos pedagógicos y perspectivas teóricas de la educación intercultural en el Caribe colombiano
Authors: Castro Suarez Celmira  Josefa , Alarcón Meneses Luis Alfonso
Published: May 2022

Dado el interés e importancia de estudios donde se entrecrucen lo intercultural y lo educativo presentamos aquí algunas reflexiones sobre los retos pedagógicos y las perspectivas teóricas de la educación intercultural. Para ello partimos de la premisa que el mundo que vivimos implica afrontar retos de distinto orden, uno de estos retos es continuar construyendo una educación capaz de formar al individuo para desenvolverse en la compleja y diversa sociedad actual. Esto significa, que la región Caribe requiere una educación que no solamente se centre en la transmisión de nuevos conocimientos y en el aprendizaje de habilidades y destrezas tecnológicas para desempeñarse en los espacios laborales, sino una educación fundamentada en el reconocimiento de la diversidad sociocultural y económica de su entorno social.
Presencia extranjera en Barranquilla: el caso de los alemanes, sus actividades económicas y el final de su influencia en la urbe caribeña, 1930-1941
Authors: Lázaro Julián Andrés
Published: May 2022

El presente trabajo tiene como objetivo describir algunas de las múltiples actividades económicas que desarrollaron los inmigrantes de origen alemán en Barranquilla durante el periodo que va de 1930 a 1941. Se expone aquí la manera como estos extranjeros se insertaron a través de diferentes ocupaciones en la dinámica económica que vivió la ciudad, siendo elementos dinamizadores de su desarrollo. El periodo de estudio corresponde a un momento de notable actividad de alemanes en Barranquilla, así como también a la última fase de su destacada participación en la vida de la urbe caribeña. Con todo ello se pretende destacar algunos rasgos de una de las colonias de extranjeros más influyentes en la historia de la ciudad.
Economía agrícola y circuitos comerciales en el Estado Soberano de Bolívar, 1857-1886
Authors: Flórez Bolívar Roicer Alberto
Published: May 2022

Este artículo estudia la agricultura en el Estado soberano de Bolívar y los circuitos comerciales que se construyeron alrededor de la economía agrícola. La idea central que se defiende es que a pesar de las limitaciones que presentaba la agricultura en cuanto a su nivel de exportación fue capaz de satisfacer las necesidades del mercado interno al ofrecerle a los habitantes del Estado los productos que necesitaban para su sustento y alimentación, permitiendo la creación y consolidación de circuitos comerciales a nivel provincial y comarcano, en los que algunos distritos desempeñaban un papel primordial como centros articuladores.
Territorialidad y ficción: ¿Una entente entre el foco españolista montevideano y la aislada Asunción?
Authors: Ribeiro Gutiérrez Ana
Published: May 2022

Montevideo es considerado un claro ejemplo de foco españolista desde el momento en que se inició el proceso revolucionario (que luego devino independentista), en 1811. Asunción, por su parte, fue ciudad-cabeza de un territorio que se aisló y proclamó tempranamente su independencia. Sin embargo, ambas ciudades habían intentado una fugaz entente. Las historiografías nacionales suelen narrar los hechos del pasado teniendo en cuenta los mapas políticos de sus respectivos países. Este artículo propone abordar ambas ciudades en el lapso 1810-1820, desde claves económicas y simbólicas que develan la ficción que encierra toda territorialidad, en tanto constructo.
Italia en Barranquilla. Año de 1938
Authors: D'Amato Castillo Guissepe , Vidal Ortega Antonino , Forbes Castillo Edwin
Published: May 2022

Texto documental extraído del libro "Los Italianos en Colombia" de 1938, que muestra un testimonio documental muy valioso que describe la Barranquilla de los años previos a la Segunda Guerra Mundial.
Revisitando un clásico: James Burney y su Historia de los Bucaneros de América. Una definición del mundo a principios del S. XIX
Authors: Marchena Fernández Juan
Published: May 2022

Entre la literatura y la historia y sobre la base de los escritos del navegante inglés James Burney el presente trabajo hace un recorrido a lo largo del siglo XVIII por el proceso de conocimiento de la navegación en los mares del planeta haciendo especial énfasis en los viajes por el Caribe.
Los marqueses de Santa Coa. Una historia económica del Caribe colombiano 1750-1810
Authors: Daza Villar Vladimir
Published: May 2022

Reseña del libro "Los marqueses de Santa Coa. Una historia económica del Caribe colombiano 1750-1810" escrito por Vladimir Daza
El reajuste del ejército neogranadino y la promulgación del Código de Milicia de 1794
Authors: Puentes Cala Mauricio
Published: May 2022

Breve reseña introductoria y transcripción del documento: Reglamento para las Milicias Disciplinadas de Infantería y Dragones del Nuevo Reyno de Granada, y Provincias agregadas a este Virreinato, elaborado en 1794, y que reposa en el fondo Secretaria de Guerra del Archivo General de Simancas en la ciudad de Valladolid (España). / Brief introductory summary and transcript of the document: Reglamento para las Milicias Disciplinadas de Infantería y Dragones del Nuevo Reyno de Granada, y Provincias agregadas a este Virreinato, created in 1794, and that rests in the Fund Secretaria de Guerra del Archivo General de Simancas in the city of Valladolid (Spain).
Has Barrio Abajo a patrimonial value or it is just a residential neighborhood?
Authors: Suárez Pérez Rosmery
Published: May 2022

Este artículo es una exploración preliminar del valor patrimonial del Barrio Abajo, no sólo como barrio fundacional de la ciudad de Barranquilla, y su significado histórico, sino en el abanico cultural que se desenlaza en su espacio urbano como red social articulada al centro histórico, y ahora valorado como patrimonio de la ciudad. El valorar dentro del Plan de Ordenamiento Territorial (POT) a Barrio Abajo como patrimonio, significaría protegerle de la demolición en aras de nuevos desarrollos urbanísticos como ampliación de vías, nuevos centros comerciales, entre otros, y aunque también goza de valor arquitectónico como el Barrio Alto Prado, busca demostrarse su valor social al ser garante de tradiciones e identidad de ciudad y por tanto necesario para el desarrollo social.
Reflexiones acerca de las consecuencias del contacto entre indios y no indios en Brasil: el caso de los indios de la ciudad de Ponta Grossa, provincia del Paraná
Authors: Barbosa de Moraes Barros Solange Aparecida , Ribeiro de Oliveira Junior Constantino , Taques Fonseca Buzato Luiz Fernando
Published: May 2022

O presente trabalho tem como propósito abordar algumas questões relacionadas aos indígenas no Brasil a fim de compreender melhor a atual situação dos índios aldeados que transitam pelas cidades em busca de alternativas de sobrevivência. Assim, a pesquisa partirá primeiramente de um estudo bibliográfico que aborda a construção da figura do índio no pensamento brasileiro, analisando posteriormente como se estabeleceu o relacionamento entre Estado (colonial e nacional), sociedade e povos indígenas a partir destas representações. Ao final, será apresentadauma reflexão acerca da condição destes indígenas, tendo como exemplo os índios da cidade de Ponta Grossa/PR, Brasil. Estas análises vislumbrarão que a história de relacionamento entre índios e não-índios no Brasil sempre foi marcada pelos conflitos, tendo em vista as diversas formas negativas de se representar o índio, e que, apesar de haver recentes ganhos no campo político e jurídico, ainda há práticas e atitudes discriminatórias.
Ulrika Gustafsson och Hanna Kurtén (red.), Zacharias Topelius Läsning för barn
Authors: Bjorvand Bjørkøy Aasta Marie
Published: May 2022

Review/Recension
港式中文转述动词 “谓、指、话” 的共时状况与历时发展
Authors: 涵韬 徐
Published: May 2022

“谓、指、话” 是港式中文里典型的转述动词。文章既讨论了它们语义、结构与功能的共时表现，又考察其来源与历时发展变化情况。其中，“谓”是从古代汉语传承至早期现代汉语并沿用至港式中文的；“指” 来自早期现代汉语，是在英语 “point out” 影响下由 “指出” 简缩而来的，可以认为是英源形式；“话” 从古代汉语保留至粤方言继而进入港式中文。“谓、指、话”的产生发展过程表明，文言、粤语、英语是港式中文的主要来源及构成成分，而早期现代汉语则是港式中文的 “底本”。
Numerical solutions of the Bagley–Torvik equation by using generalized functions with fractional powers of Laguerre polynomials
Authors: Yüzbaşı Şuayip , Yıldırım Gamze
Published: May 2022

In this study, a collocation approach is presented to solve Bagley–Torvik equation, which is a class of fractional differential equations. As most fractional differential equations do not have exact analytical solutions, it is needed numerical methods. This study is important because it presents a numerical method for fractional differential equations. The main purpose of this method is to obtain the approximate solution based on Laguerre polynomials of the Bagley–Torvik equation. To date, a collocation method based on the Laguerre polynomials has not been studied for the solutions of the Bagley–Torvik equation. This reveals the novelty of the study. The approximate solution is sought in form of the fractional powers of the Laguerre polynomials. By using the Caputo derivative, the matrix relation is created for term with fractional derivative in the equation. Similarly, the matrix relation of second derivative is computed in equation. Then, by using these matrix relations and the collocation points, the Bagley–Torvik problem is converted into a system of the linear algebraic equations. The solution of this system gives the coefficients of the assumed solution. Secondly, an error estimation method is given with the help of the residual function and also the Laguerre polynomial solution is improved by using the estimated error function. Then, the method is applied to four examples and the obtained numerical results are shown in tables and graphs. Also, the comparisons are made with other methods in the literature and so the presented method gives better results than other methods.
Design, preparation, and functionalization of nanobiomaterials for enhanced efficacy in current and future biomedical applications
Authors: Ramburrun Poornima , Khan Riaz A. , Choonara Yahya E.
Published: May 2022

Biocompatible, attuned, and congruent stimuli-responsive polymers of synthetic and plants and animals-based origins are essential raw materials for constructing bio-matching scaffolds, devices, and vehicles for payload deliveries, tissue engineering, therapeutics, and diagnostic purposes, and also as fill-in materials at biosites for various biomimetic applications. The nanobiomaterials for nanobiotechnology, nanopharmaceuticals, and nanobioengineering requires to have fit-in intrinsic chemical, physical, physico-chemical, mechanical, biological, and chemo-biological characteristics. The developed nanomaterials are also required to be receptive and biomimicking in quality, and they must not be toxic at any stage of use or implantation, minimally or of zero order degradation together with aging and use-related degradation, and last a life-time. The biomaterial at the upgraded scale needs to possess intricate characteristics equivalent to the biological materials, and compatible to the biological-sites during transportation, delivery, and site-unloading, and use. Recent developments in nanobiomaterial substrate designs and structure, characteristics, design requirements, chemo-biological interface related bio-systems response-compatibility, biomaterial synchronized, contemporaneous, and evolving applications in health care, therapeutics, nanomedicine, bio-hazard prevention, toxicity and ways of toxicity-control are outlined. The structure-function relationship, scope and limitations, structural and functional classes, and diversified biological outreach are discussed.
The Orseolos
Authors: Báling Péter
Published: May 2022

This study examines the lineage of the Orseolo dynasty: the origins of the family and the genealogical data on its members. In the Hungarian historiography the ancestry of the Orseolos was a subject of lengthy debates, the present paper therefore aims to clarify all those questions that arose during these disputes in the light of the available sources. Since Peter – a member of the dynasty – arose on the throne of the Hungarian Kingdom in the 11th century, the study not only discusses in detail the genealogy of the king, but his rule and political role as well.
A Hungarian-Croatian Aristocrat from a new Perspective
Authors: Végh Ferenc
Published: May 2022

Peter Zrinyi’s (†1671) name became inséparable from his participation in the conspiracy led by palatine Ferenc Wesselényi (also known as Zrinsko-Frankopan plot) which is the most examined period of his lifetime. The Croatian historiography has been focusing on his role in the movement, still considering him an early representative of the thought of independence. Peter Zrinyi’s literary activities have been researched relating to the political ones too. His military career, however, is practically unexamined; not even its major stages are known. Hungarian historians having national sympathies could also be blamed for this backlog due to the fact that they totally neglected his person pushing Nicholas Zrinyi forward in his stead. The present paper aims to outliné Peter Zrinyi’s advancement from a new perspective, namely in interaction with that of Nicholas Zrinyi. As we will see, the first decade spent together in Mura-köz had playéd an important rolé that Peter oriented himself towards Croatian territories.