bluuebunny/crossref_metadata_2025 huggingface dataset:
PEMODELAN FAKTOR EKONOMI MAKRO TERHADAP HARGA SAHAM TELKOM MENGGUNAKAN REGRESI SPLINE TRUNCATED MULTIVARIABEL DILENGKAPI GUI R
Authors: Saidah Lulu Maulatus , Suparti Suparti , Sudarno Sudarno
Published: January 2023

Stock prices are an important thing that investors should know before investing. Volatile stock prices require investors to know the factors that influence their changes. Stock price instability makes it very difficult for investors to make investments and affects the integrity they get. One of the factors that affect stock prices is macroeconomic factors consisting of rupiah exchange rate (X1), inflation (X2), and SBI interest rate (X3). A statistical method that can be used to model fluctuating data is spline nonparametric regression. This study aims to model macroeconomic factors against Telkom's stock price using multivariable truncated spline nonparametric regression with optimal knot point selection methods that minimize Generalized Cross Validation (GCV). Many knots used are a combination of 1 and 2 and the order used is a combination of 2, 3, and 4. The best multivariable truncated spline model is achieved on a knot combination (2,2,2) with the order X1, X2, X3 being 3, 2, 2 which results in an R2 value of 92.71% included in the strong model criteria. In the evaluation of model performance obtained a MAPE value of 1.857% which shows the model has excellent forecasting ability. In this study, a Graphical User Interface (GUI) program was formed R that can facilitate data analysis and produce more attractive display output.
PENERAPAN DIAGRAM KONTROL MEWMA DALAM PENGENDALIAN KUALITAS PRODUKSI KERIPIK SINGKONG PADA UMKM DI KOTA SEMARANG
Authors: Nesari Nesari , Mustafid Mustafid , Widiharih Tatik
Published: January 2023

Quality is the main thing that needs to be considered by every company. Ceriping Bintang Putra Bu Slamet is an UMKM (Usaha Mikro, Kecil dan Menengah) that produces cassava chips. During production, there are three quality characteristics, namely large crumbs defects, small crumbs, and chips sticking together. It is important to control these defects to produce quality products according to customer needs. This research was conducted from July to August 2021. The purpose of this study was to control the production quality of cassava chips using the Multivariate Exponentially Weighted Moving Average (MEWMA) control chart and multivariate process capability analysis. The MEWMA control chart is used to detect the shift in the process average which is more sensitive using weights (λ), while the process capability analysis is used to determine the process performance. The implementation of the MEWMA control chart is carried out in two stages, namely phase I control to obtain the optimal weighting and control limits so that it can be used in phase II control to monitor the average process for the next period. Based on the results of the analysis, the optimal weighting is λ =0,4 with BKA=201,7434, GT=113,538, and BKB=0 in phase I control. Then, the results of phase II control show a shift in the average process in a better direction. In addition, the results of the process capability analysis show an improvement in the performance of the production process from July 2021 to August 2021 with MCpm values of 0,535 and 1,147
PENERAPAN TUNING HYPERPARAMETER RANDOMSEARCHCV PADA ADAPTIVE BOOSTING UNTUK PREDIKSI KELANGSUNGAN HIDUP PASIEN GAGAL JANTUNG
Authors: Putri Tita Aulia Edi , Widiharih Tatik , Santoso Rukun
Published: January 2023

Heart failure is the number one cause of death every year. Heart failure is a pathological condition characterized by abnormalities in heart function, which results in the failure of blood to be pumped to supply metabolic needs of tissues. The application of data mining and computational techniques to medical records can be an effective tool to predict each patient's survival who has heart failure symptoms. Data mining is a process of gathering important information from big data. The collection of important information is carried out through several processes, including statistical methods, mathematics, and artificial intelligence technology. The AdaBoost method is one of the supervised algorithms in data mining that is widely applied to make classification models. Hyperparameter Optimization is selecting the optimal set of hyperparameters for a learning algorithm. AdaBoost has hyperparameters requiring a classification process set, namely learning rate and n_estimators. RandomSearchCV is a random combination method of selected hyperparameters used to train the model. This research uses heart failure patient data collected at the Faisalabad Institute of Cardiology and at the Allied Hospital in Faisalabad (Punjab, Pakistan) from April to December 2015. The research uses learning rate: [-2.2] (log scale), n_estimators start from 10 to 776, and Kfold=5 and produces the best hyperparameters in learning rate=0.01 and n_estimators=443 with an accuracy value of 0.85 and AUC value of 0.897.
PEMODELAN INDEKS PEMBANGUNAN MANUSIA DI JAWA TENGAH MENGGUNAKAN METODE REGRESI RIDGE DAN REGRESI STEPWISE
Authors: Sulistianingsih Erna , Suparti Suparti , Ispriyanti Dwi
Published: January 2023

The Human Development Index (HDI) is an important indicator in measuring the success of national development. Central Java with a high population can be considered as an obstacle and a driver of development. To find out the factors that affect HDI, it is necessary to make a model. One of the statistical methods that can be used is multiple linear regression analysis. However, in modeling multiple linear regression there are assumptions that must be met, namely linearity, normality, homoscedasticity, non-autocorrelation, and non-multicollinearity. If the non-multicollinearity assumption is not met, then another alternative is needed to estimate the regression parameters. Several methods that can be used are ridge regression and stepwise regression methods. The best model selection is done by looking at the smallest Mean Square Error (MSE) value. In this study, ridge and stepwise regression were applied to Central Java HDI data in 2021 and the factors that influence it, namely life expectancy at birth, expected years of schooling, average length of schooling, per capita expenditure, percentage of poor people, and unemployment open. Based on the Variance Inflation Factor (VIF) value of more than 10, it can be concluded that there is a multicollinearity violation. Modeling with stepwise regression produces the best model, with the smallest MSE value. The R square model value of 0,99 indicates that the model is included in the criteria for a strong model.
Total Intravenous Anesthesia (TIVA) pada Bedah Jantung Koroner
Authors: Yulia Mefri , Hadinata Yudi
Published: January 2023

Bedah jantung koroner merupakan jenis operasi jantung yang paling sering dilakukan pada pasien dewasa. Pada penelitian yang dilakukan tahun 2011-2014 angka mortalitas bedah jantung koroner pada pasien dengan multipel lesi pembuluh darah sebesar 27,8%.Pasien yang dipertimbangkan untuk dilakukan bedah jantung koroner memerlukan penilaian risiko operatif, pemeriksaan menyeluruh dan manajemen perioperatif yang baik oleh dokter anestesi. Pemilihan teknik dan agen anestesia pada bedah jantung koroner telah berkembang pesat dengan tersedianya obat intravena yang memiliki durasi singkat dan mudah dititrasi seperti propofol dan remifentanyl yang memberikan efek sinergis dibandingkan penggunaan opioid dosis tinggi. Oleh karena itu, teknik total intravenous anesthesia (TIVA) mulai banyak dipilih seiring dengan perkembangan obat dan tersedianya alat seperti smart-pump infusion yang memungkinkan obat intravena untuk mencapai efek klinis yang diharapkan dan memberikan angka harapan hidup dan luaran yang lebih baik hingga beberapa tahun pascabedah.
Laparoskopi Hemihepatektomi pada Hepatoseluler Karsinoma Hemiliver Dextra Et Causa Hepatitis B
Authors: Andriani Ika Jati Setya , Sambdani Ibnu Siena
Published: January 2023

Latar Belakang: Reseksi hati untuk karsinoma hepatoseluler (HCC) saat ini dikenal sebagai prosedur yang lebih aman daripada sebelumnya karena kemajuan teknis dan perbaikan dalam manajemen pasien pascaoperasi dan tetap menjadi pengobatan lini pertama untuk HCC pada sirosis kompensasi. Hepatektomi adalah strategi pengobatan kuratif yang umum digunakan untuk pasien HCC stadium awal dan awal dengan fungsi hati yang dipertahankan. Teknik laparoskopi telah terbukti mempercepat pemulihan, meningkatkan nyeri pascaoperasi, dan menghasilkan kosmetik yang lebih baik daripada pendekatan terbuka.Kasus: Pasien laki-laki usia 51 tahun datang dengan nyeri perut kanan sejak 2 minggu, riwayat asma, hipertensi, penyakit jantung, sedasi, operasi, demam, sesak napas, batuk, pilek disangkal. Pasien tampak sakit sedang dengan kesadaran kompos mentis. Vital sign : tekanan darah  129/77 mmHg, laju jantung 83x/menit regular, isi dan tengangan cukup, laju napas 20x/menit, suhu = 36,2°C, saturasi oksigen 100% room air. Pada pemeriksaan laboratorium, ditemukan HBsAg = positif, AFP = 3,46 ng/ml, anti HCV = 0,09 IU/L, SGOT = 26 U/L, SGPT = 22 U/L. Pada pemeriksaan multislice computed tomography abdomen (MSCT abdomen), ditemukan hepatomegali disertai massa solid dengan area nekrotik di dalamnya pada segmen 8 hepar dan limfadenopati interaortocava.Pembahasan: HCC adalah tumor primer hati dan merupakan lebih dari 90%   tumor primer hati. HCC sekarang menjadi penyebab paling umum kelima kanker di seluruh dunia. Anestesi umum dipertahankan dengan anestesi volatil (isofluran sevofluran, desfluran, nitrous oxide), anestesi intravena (propofol, dexmedetomidine, ketamin, opiat), atau kombinasi dari semuanya, relaksan otot kerja pendek dan menengah lainnya (atracurium, rocuronium, vecuronium). Reseksi hati membawa risiko kehilangan darah yang melekat dengan pembedahan diseksi inferior vena cava (IVC), vena portal, dan vena hepatik dan transeksi parenkim yang sangat vaskularisasi.Kesimpulan: Hepatektomi laparoskopi menghindari kerugian dari hepatektomi standar pada pasien yang dipilih dengan benar dan bermanfaat untuk kualitas hidup pasien, karena merupakan prosedur invasif minimal.
Optimization of Liquid Soap Preparation Formula with the Addition of Black Rice (Oryza Sativa L. Indica) Extract as Anti-Radical Free based Virgin Coconut Oil (VCO)
Authors: Imamsyah Ragil Agnes Safira , Paramita Vita
Published: January 2023

An imbalance in the body's number of antioxidants and free radicals can cause oxidative stress and trigger various degenerative diseases (WHO, 2016). One way to prevent free radicals from entering the body is to bathe with soap. Black rice extract can be an antioxidant in soap because it contains anthocyanin pigments and has high bioactive compounds (Chakuton et al., 2012). Selection of Virgin Coconut Oil (VCO) as a raw material for soap because it has a high lauric acid content and is helpful for moisturizing and smoothing the skin (Afrozi et al., 2021). This study aimed to analyze the quality of liquid soap from the hydrolyzed Virgin Coconut Oil (VCO) and the effect of using bases KOH, NH4OH, and black rice extract accompanied by varying base concentrations, time, and temperature treatments. The independent variables for process optimization were the concentration of KOH: NH4OH (30:70, 50:50, 70:30)%, stirring time (65, 85, 105) minutes, and operating temperature (60, 75, 90) °C. Based on the results obtained, the optimum level of FFA (resulting in a small FFA%) was obtained with the minimized variable conditions, namely using a concentration of 16,4% KOH, and an operating temperature of 49,7 °C, a stirring time of 51.4 minutes, and composite desirability of 0,895897.
Optimization of Biosorbent on Cd(II) Metal Biosorption Using Duck Eggshell Waste
Authors: Tasmalia Ria , Prameswari Nida Hamidah , Paramita Vita
Published: January 2023

Every year the production of duck eggs in Indonesia has increased, this case leads to an increase in the waste of duck eggshells. Duck eggshell waste has components that can be utilized into a biosorbent. To improve the quality of the biosorbent, can be done with an activation method and immobilization method. The purpose of this study was to determine the effectiveness of biosorbents made from duck eggshell waste in absorbing Cd(II) metal. In this study, duck eggshells were activated with physical activation by heating in a furnace at a temperature of 900oC for 2 hours. Independent variables of this study are biosorbent mass, contact time and concentration of cadmium solution. Critical values for Cd levels optimization conditions are accomplished when the biosorbent mass 1.45 grams, contact time 100 minutes and Cd solution concentration 86 ppm with a percentage decrease in Cd levels in the amount of 89%.
Vlastnosti úloh z organické chemie a biochemie vyplývající z položkové analýzy oborového testu z chemie v rámci přijímacího řízení na Přírodovědeckou fakultu Univerzity Karlovy
Authors: Šrámek Martin , Teplá Milada
Published: January 2023

Článek představuje výsledky položkové analýzy oborových testů z chemie zadávaných pro účely přijímacího řízení na Přírodovědecké fakultě Univerzity Karlovy v letech 2016 až 2019 a navazuje na dříve publikované články zaměřené na obecnou a anorganickou chemii. Cílem zkoumání byla identifikace nejvíce obtížných úloh pro uchazeče o studium a rovněž necitlivých úloh, tj. takových, které nedostatečně rozlišovaly úspěšné uchazeče od uchazečů neúspěšných. Obtížné úlohy byly identifikovány na základě vypočtení indexu obtížnosti. Necitlivé úlohy byly stanoveny na základě výpočtu koeficientů ULI(1/2) a RIR.Výsledky položkové analýzy odhalily, že v rámci organické chemie a biochemie byly pro uchazeče obtížné úlohy ze čtyř okruhů (reakce v organické chemii, konstituce látek a izomerie, klasifikace organických látek, enzymy). Necitlivé úlohy byly detekovány u sedmi témat, která obsahovala alespoň jednu necitlivou položku (např. kyselost a zásaditost organických látek, vzorce v biochemii, biochemické reakce, . . . ). Necitlivost úlohy často souvisela s vysokým počtem kroků nutných k jejímu úspěšnému vyřešení.
Sprawozdanie z konferencji naukowej pt.: „Molestowanie seksualne. Analiza zjawiska i przeciwdziałanie” 8 marca 2021 r., Wydział Studiów Edukacyjnych Uniwersytetu im. Adama Mickiewicza w Poznaniu (on-line)
Authors: Świeżek Klarysa , Jezierska Julia
Published: January 2023

Sprawozdanie z konferencji naukowej pt.: „Molestowanie seksualne. Analiza zjawiska i przeciwdziałanie” 8 marca 2021 r., Wydział Studiów Edukacyjnych Uniwersytetu im. Adama Mickiewicza w Poznaniu (on-line)
Portret Stanisława Staszica w opowiadaniu Mary Hoare pt. Nie sądź
Authors: Laskowski Maciej
Published: January 2023

The subsequent study expands upon the connections between Stanisław Staszic and English literature. Specifically, the paper portrays the Polish Enlightenment thinker as an inspiration of Mary Anne Hoare’s short story entitled Judge not! (Polish Nie sądź) with Staszic as its main protagonist. The ensuing presentation appears very important to many readers, including scholars who (falsely) attribute the story’s authorship to Charles Dickens. The research aims to verify if the idiosyncrasies conveyed by Hoare in her narrative were actually the Pole’s characteristics. At this point, the paper examines the specifics attributed by the Irish authoress to Staszic specifically, making him the focal point of her work. In order to accomplish the set goals, the behind the scenes and the essence of Hoare’s work have been illustrated. Finally, I hope that the article will help to promote the story which has nearly slipped into oblivion and to underline Staszic’s multifaceted activity and life. It has earned him a place in English literature through the pen of a female writer from Ireland.
The Outline of Communal ‘Ars Moriendi’ in Egalitarian Transhumanism
Authors: Polowczyk Łukasz Paweł
Published: January 2023

This paper outlines the proposal for an egalitarian, transhumanist, and communal version of ars moriendi that should be coherent and meet the consequentialist criteria of the principle of minimizing anti-values and maximizing values, especially the ethical values of freedom and happiness. Transhuman-ist augmented dying (AD) refers to the extended body-mind, free from harmful religious and political ideologies. At present, a feasible art of dying can be systematically supported by anesthetics and psy-chedelics (entheogens), computer games, virtual reality, and good death machines. Its egalitarian form requires a deeply democratic society, and its progress may need a transition to a type 1 society on the Kardashev scale.
The COVID-19 Pandemic Between Bio-Ethics, Bio-Law and Bio-Politics: A Case Study on The Italian Experience of The DuPre Commission
Authors: Testoni Ines
Published: January 2023

The aim of this qualitative study was to consider the question of whether the Italian political management of the pandemic respected the European bio-ethical and bio-juridical approaches in light of the principles of autonomy, dignity, integrity and vulnerability. As no specific consolidated literature exists on the subject, the Italian situation was taken into consideration, specifically the work of a spontaneous commission (DuPre) that collected the reflections of academics and researchers interested in discussing political decisions for the management of the emergency, which was the coronavirus disease (COVID-19) pandemic. The analysis took into account the contributions of scholars during two conferences (without proceedings), which were transcribed and examined. From the texts processed with a thematic analysis, three main themes emerged: ‘pandemic as a state of exception, sovereignty and crisis of democracy’, ‘the value of doubt and refutation’ and ‘elimination of informed consent between persuasion and blackmail’. In this paper, the final bio-political considerations on the European approach and the management of the COVID-19 pandemic in Italy are presented.
The Central Role of Schools in Promoting Death Education Interventions
Authors: Fagnani Giuditta
Published: January 2023

Avoidance of discussion about death is common in contemporary Western societies. Plenty of literature substantiates that (at the beginning of the sentence), the actual tendency toward death denial can produce many negative effects such as the suppression of death-related thoughts and emotions. Death Education aims to strengthen the psychological anchors that allow us to recognize the profiles of anguish, prevent the decompensating factors of pathological mourning and process the experiences of loss at all ages. The article aims to support the usefulness and use of Death Education interventions in schools and their central role in promoting these interventions.
Platone, Prm. 133b4- c1 / 134e9- 135b2. Quali logoi nella gumnasia per un tis refrattario alla persuasione e sensibile alle contraddizioni come Antistene?
Authors: Mazzara Giuseppe
Published: January 2023

In this study, I show how Plato in the Parmenides reprises the encounter with the Phaedo’s Antisthenes, whom I elsewhere assumed to be one of the various tis that get examined in the dialogue. Now, with the Parme­nides’ tis, a similar situation arises: this Antisthenes embodies such characteristics as being “an expert in many areas”, “not without natural gifts” and “capable of following with critical intelligence” the logoi taken from “distant premises.” In the four logoi of the gumnasia, I highlight how Plato, in developing his exercise, proceeds on his own way without openly arguing with any tis and how, despite his detached attitude, his hodos, while interweaving with that of his colleague Antisthenes, enters into a conflict. I then demonstrate how the two paths, despite having a common aporetic beginning (the objections of Gorgias to Parmenides and the testimony of Proclus against Antisthenes), at times overlap and at times are mutually exclusive. From this, I also argue that whoever wrote the dialogue must have been aware that the path, although appar­ently linear and rectilinear, was in fact bumpy and tortuous.
The Figure of Socrates in Numenius of Apamea: Theology, Platonism, and Pythagoreanism (fr. 24 des Places)
Authors: Volpe Enrico
Published: January 2023

Numenius is one of the most important authors who, in the Imperial Age, deal with the figure of Socrates. Socrates is important in the Platon­ic tradition, in particular in the sceptical tradition, when the Socratic dubitative “spirit” of the first Platonic dialogues became important to justify the “suspension of judgement.” Numenius criticises the whole Academic tradition by saying that the Academics (particularly the sceptics) betrayed the original doctrine of Plato and formulated a new image of Socrates. For Numenius, Socrates plays a central role because Plato would have inherited his doctrine. What does Socrates’s doctrine consist in? According to Numenius, Socrates theorised a “doctrine of three Gods” (which can be likely found in the second Platonic epistle) which is strictly bound up with the main aspect of Plato’s thought. In fact, in Numenius’s view, Plato belongs to a genealogy which can be linked to Pythagoras himself. From this perspective, Numenius says that Socrates’s original thought is a theology which also belongs to the Pythagorean tradition and which Plato further developed. For Nume­nius, Socrates is not the philosopher of doubt, but a theologian who first theorised the existence of three levels of reality (Gods), which is also the kernel of Numenius’s metaphysical system. For this reason, Numenius puts Socrates within a theological genealogy that begins with Pythago­ras and continues with Socrates and Plato, and that the Academics and the Socratics failed to understand.
Stability of stationary solutions to the three-dimensional Navier-Stokes equations with surface tension
Authors: Watanabe Keiichi
Published: January 2023

This article studies the stability of a stationary solution to the three-dimensional Navier-Stokes equations in a bounded domain, where surface tension effects are taken into account. More precisely, this article considers the stability of equilibrium figure of uniformly rotating viscous incompressible fluid inR3{{\mathbb{R}}}^{3}, which are rotationally symmetric about a certain axis. It is proved that this stability result can be obtained by the positivity of the second variation of the energy functional associated with the equation that determines an equilibrium figure, provided that initial data are close to an equilibrium state. The unique global solution is constructed in theLp{L}^{p}-in-time andLq{L}^{q}-in-space setting with(p,q)∈(2,∞)×(3,∞)\left(p,q)\in \left(2,\infty )\times \left(3,\infty )satisfying2/p+3/q<12\hspace{0.1em}\text{/}p+3\text{/}\hspace{0.1em}q\lt 1, where the solution becomes real analytic, jointly in time and space. It is also proved that the solution converges exponentially to the equilibrium.
Behavior of circular skirted footing on gypseous soil subjected to water infiltration
Authors: Aljuari Khawla A. , Fattah Mohammed Y. , Alzaidy Mohammed N. J.
Published: January 2023

Skirted footings are used to increase the final carrying capacity of shallow foundations resting on unstable soil and to decrease settling by limiting the soil beneath them. Skirted footings are utilized as an alternative to pile driving in poor strength soils at the top layer, such as gypseous soil, to save project costs and time spent installing piles while maintaining excellent performance. The settling of circular skirted footings resting on gypseous soil subjected to loading, infiltration, and collapsing stages was investigated using numerical calculations in this research study to determine their stability under environmental loadings. Finite element analyses were carried out using the commercially available software GEO-STUDIO. The stage of gypseous soil and variable skirt depth to footing diameter ratios (d/D) were taken into consideration. The findings reveal that both the soil stage and the skirt embedment ratio have a substantial impact on the ultimate bearing capacity and the settlement of weak soil, with the skirt embedment ratio increasing resulting in superior skirted footing performance. Furthermore, the improvement in settlement for the loading stage is the smallest, whereas the value for the collapsing soil stage is the largest.
Licensing Case-mismatches and dependent plural markers in Korean left-node-raising
Authors: Kim Jeong-Seok , Choi Seojin , Lee Jee Young
Published: January 2023

Left-node-raising (LNR), as a mirror image of right-node-raising (RNR), is a phenomenon in which the leftmost constituent is shared by the two conjuncts. In this paper, we empirically and theoretically explore two distinctive properties of LNR in Korean: licensing Case-mismatches of a shared element and the dependent plural markertul. We argue that the first conjunct Case-licensing of the shared element in LNR is crucial across Case types. We thus confirm the explanatory edge of the scrambling-plus-proanalysis of LNR, nullifying previous symmetric analyses of LNR such as across-the-board scrambling and multidominance. Additionally, we argue that LNR is not a mirror image of RNR in that symmetric analyses may explain the distribution of the dependent plural marker in RNR but not that of the dependent plural marker in LNR. Therefore, we argue against a unified analysis of RNR and LNR. We further show that the island effect of LNR is evidence of the scrambling-plus-proanalysis of LNR.
Linguistic complexity of public legal information texts for young persons
Authors: Mamac Monaliza Hernandez
Published: January 2023

The present study explores the linguistic complexity (LC) of public legal information (PLI) texts for young persons by deploying the Hallidayan model of lexical density and grammatical intricacy. It examines how the Australian legal statutes’ grammatical intricacy and lexical density are reformulated into PLI texts to make them more accessible for a specific vulnerable group. The findings reveal that although the PLI texts were claimed to be written in plain language, they trade some types of complexity for others. The paper extends Halliday’s model of complexity by adding lower rank complexes and embedded clause complexes as realisations of intricacy and density. It proposes “embedded intricacy” as a feature of a hybrid of spoken and written language. Furthermore, the study suggests reconsidering how law can be recontextualised for young persons in a more accessible way.
Preparation of zwitterionic ionic surfactants-based sulphonyl for steel protections: Experimental and theoretical insights
Authors: Shafek Samir H. , Ghiaty Eman A. , El Basiony Nasser M. , Badr Emad A. , Shaban Samy M.
Published: January 2023

Designating an organic inhibitor with a specific chemical structure that actively participates in steel protection by increasing adsorption on the steel surface. Based on that, we synthesized three zwitterionic surfactants based on azomethine with different hydrophobic chain lengths labeled ZWSO, ZWSD, and ZWSH. The presence of azomethine group, electrons, and heteroatoms in the zwitterionic surfactant’s amphipathic structure helped to improve C-steel protection. Their inhibitory activity toward steel corrosion was investigated utilizing electrochemical impedance spectroscopy (EIS), gravimetrical, and potentiodynamic polarization techniques. Importantly, the surfactant tail influenced corrosion inhibition performance; as surfactant tail length increased, so did inhibition efficiency due to increased adsorption affinity. The inhibition efficiencies of ZWSO, ZWSD, and ZWSH are 87.15, 89.82, and 91.36%, respectively. Tafel data clarified that ZWSO, ZWSD, and ZWSH inhibitors behave as mixed-type inhibitors following the modified Langmuir isotherm. The inhibitors can adsorb physiochemically on the steel surface with ∆G
ads ranges from −38.48 to −44.6 kJ mol−1. The SEM confirms that the morphology of C-steel becomes smoother because of inhibitor adsorption. The DFT and MCs output data supported the experimental performance of the tested ZWSO, ZWSD, and ZWSH inhibitors and especially their dependence on surfactant tail length.
Association Between Patient and Facility Characteristics and Rehabilitation Outcomes After Joint Replacement Surgery in Different Rehabilitation Settings for Older Adults: A Systematic Review
Authors: Osundolire Seun , Mbrah Attah , Liu Shao-Hsien , Lapane Kate L.
Published: January 2023

Background and Purpose:

In the United States, an exponential increase in total hip arthroplasty (THA) and total knee arthroplasty (TKA) demand has occurred over the last 2 decades. Evidence suggesting patients receiving inpatient rehabilitation following a TKA or THA experience similar outcomes as those with rehabilitation in other settings led to dramatic shifts in postsurgical care settings owing to Centers for Medicare & Medicaid Services (CMS) payment reforms. A contemporary synthesis of evidence about the association between patient and facility factors and outcomes from older adults undergoing THA or TKA in the United States is needed.

Methods:

To identify eligible studies, we searched PubMed, Scopus, and CINAHL. We followed PRISMA guidelines to identify articles evaluating either patient or facility factors associated with outcomes after THA or TKA for older adults who may have been cared for in inpatient settings (ie, inpatient rehabilitation or skilled nursing facility [SNF]). Eligible articles were conducted in the United States and were published between January 1, 2000, and December 31, 2021.

Results:

We included 8 articles focused on patient factors and 9 focused on facility factors. Most included older adults and the majority were White (in those reporting race/ethnicity). Most studies evaluated outcomes at discharge and showed that patients admitted to inpatient rehabilitation facilities had either similar or better functional outcomes (mobility, self-care, and functional independence measure (FIM) score) and lower length of stay compared with those in SNFs. Few studies focused on home health care.

Conclusions:

The systematic review focused on older adults showed that findings in these patients are consistent with previous research. Older adults undergoing THA/TKA had acceptable outcomes regardless of postsurgical, inpatient setting of care. Research conducted after CMS payment reforms, in home health care settings, and in more diverse samples is needed. Given the known racial/ethnic disparities in THA/TKA and the shifts to postsurgical home health care with little regulatory oversight of care quality, contemporary research on outcomes of postsurgical THA/TKA outcomes is warranted.
Control of G2Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex
Authors: Roussat Melanie , Jungas Thomas , Audouard Christophe , Omerani Sofiane , Medevielle Francois , Agius Eric , Davy Alice , Pituello Fabienne , Bel-Vialar Sophie
Published: January 2023

During development, cortical neurons are produced in a temporally regulated sequence from apical progenitors, directly or indirectly, through the production of intermediate basal progenitors. The balance between these major progenitor types is critical for the production of the proper number and types of neurons, and it is thus important to decipher the cellular and molecular cues controlling this equilibrium. Here we address the role of a cell cycle regulator, the CDC25B phosphatase, in this process. We show that, in the developing mouse neocortex of both sex, deleting CDC25B in apical progenitors leads to a transient increase in the production of TBR1+neurons at the expense of TBR2+basal progenitors. This phenotype is associated with lengthening of the G2phase of the cell cycle, the total cell cycle length being unaffected. Usingin uteroelectroporation and cortical slice cultures, we demonstrate that the defect in TBR2+basal progenitor production requires interaction with CDK1 and is because of the G2phase lengthening in CDC25B mutants. Together, this study identifies a new role for CDC25B and G2phase length in direct versus indirect neurogenesis at early stages of cortical development.

SIGNIFICANCE STATEMENTThis study is the first analysis of the function of CDC25B, a G2/M regulator, in the developing neocortex. We show that removing CDC25B function leads to a transient increase in neuronal differentiation at early stages, occurring simultaneously with a decrease in basal intermediate progenitors (bIPs). Conversely, a CDC25B gain of function promotes production of bIPs, and this is directly related to CDC25B's ability to regulate CDK1 activity. This imbalance of neuron/progenitor production is linked to a G2phase lengthening in apical progenitors; and using pharmacological treatments on cortical slice cultures, we show that shortening the G2phase is sufficient to enhance bIP production. Our results reveal the importance of G2phase length regulation for neural progenitor fate determination.
Speakers’ Choice of Frame Reveals Little About Their Trait Emotions but More About Their Preferences and Risk Perception
Authors: Mayiwar Lewend , Løhre Erik
Published: January 2023

People’s decisions depend on how situations are described or framed to them. But how do speakers frame outcomes to others? What factors predict whether a speaker chooses to frame an investment opportunity in terms of its chances of failure or success? Drawing on the appraisal tendency framework, we investigated whether emotions associated with uncertainty (worry) might increase speakers’ preference for negative framing, whereas emotions associated with certainty (anger) might increase speakers’ preference for positive framing. Across two well-powered preregistered studies (NTotal = 1,350), participants responded to measures of dispositional worry and anger and completed framing tasks in different contexts. We told participants that a job applicant/investment in a medical treatment had an estimated chance of failure vs success (e.g., 40% chance of failure and 60% chance of success) and asked them whether they would describe the predicted outcome to their manager in terms of chances of failure or chances of success. Overall, we found little evidence for our hypothesized influence of dispositional worry and anger on framing using our preregistered analysis. However, exploratory analyses revealed that the predicted associations appeared when participants perceived high levels of risk in the decision scenarios. A stronger effect on frame preference was found for risk perception and willingness to recommend a decision, indicating that frames reveal more about such idiosyncratic responses than about emotional traits. Preregistrations, data, code, and materials can be found at https://osf.io/3e98a/.
The Future of Multilateralism and Global Development: Opportunities for Constitutive and Functional Reform
Authors: Singh J. P. , Woolcock Michael
Published: January 2023

In response to the numerous challenges facing contemporary multilateral organizations, and indeed the very idea of multilateralism itself, many have called for “wholesale change” yet few have provided specific details on substance or articulated how any such reforms might be supported (politically, financially) or implemented. We summarize key insights from a recent global initiative that sought to both provide a critical assessment of multilateralism at different units of analysis and offer credible corresponding responses, doing so within a basic framework distinguishing between multilateralism’s constitutive elements (e.g., the creation, organization, and collective understandings of the UN system) and its functional components (everyday activities such as budgets and hiring practices). This collection of fourteen papers and six commentaries highlights specific ways in which different kinds of political, policy, and procedural challenges might be addressed, including strategies to adopt more adaptive management practices, ensure compliance with dues-paying rules, and diffuse secession threats; enact difficult trade-offs between imperatives for transparency, accountability, and confidentiality; learn from regulatory innovations in trade and investment rules to strengthen labor, human rights, and the environment; formulate workable domestic and global rules for multilateral cooperation; enhance data on, studies of, and policy responses to rising inequalities; implement potential technical fixes to redress debilitating “binding constraints”; promote greater staff diversity (geographically, demographically, ideologically); forge greater complementarity between regional, “new” (Southern-based) and “established” multilateral organizations; secure the substantive contributions of small states; and respond proactively to the shifting contours of geopolitical rivalries, opportunities, and imperatives.
Turmeric Extraction (Curcuma Longa L) Using The Reflux Method And Characterization
Authors: Kusumaningrum Maharani , Ardhiansyah Hanif , Putranto Andika Wicaksana , Trihardini Anita , Kinanti Putri Arum , Maslahah Duwi Naely , Harianingsih Harianingsih
Published: January 2023

Turmeric (Curcuma longa L) is one of the many spices that grow on the Asian continent, especially Southeast and South Asia, which can be utilized to its full potential, especially the antioxidant compounds contained in curcuminoids. This study aims to determine the effect of different forms of turmeric, powder and fresh, on the extraction using the reflux extraction method and antioxidant activity using the DPPH method (2,2-Diphenyl-1-PicrylHydrazyl). The reflux extraction process was carried out using distilled water with three variations of sample forms, turmeric powder, fresh turmeric (grated turmeric and pieces of turmeric) with a solute/solvent ratio (w/v) (1:5). The viscous extract in the form of a paste was obtained after the distillation process and solvent evaporation. The best extracts and essential oils obtained were extracts from powdered turmeric samples with yields of 8.28 (% w/w) and essential oils of 0.44 g, which were clearer than the other two samples. The analysis showed that the sample of turmeric with the highest antioxidant activity was a sample of freshly grated turmeric with an IC50 value of 114.7 ppm with a moderate level of antioxidant activity. The cut turmeric sample has an IC50 value of 158.3 ppm, which is included in the weak antioxidant activity. The powdered turmeric sample has an IC50 value of 134.1 ppm with moderate strength.
La reparación a las víctimas de abuso sexual infantil: la necesaria reforma de los mecanismos de compensación
Authors: Arantegui Arràez Laura , Tamarit Sumalla Josep Maria
Published: January 2023

Aunque se suele aceptar la necesidad de que las víctimas menores de edad reciban una especial protección, los mecanismos de compensación vigentes no están diseñados para dar respuesta a sus necesidades específicas. Tras un examen del sistema público de ayudas y de las decisiones de los tribunales españoles respecto a la responsabilidad civil en favor de las víctimas de abuso sexual infantil, se formulan propuestas para diseñar un sistema de compensación justo y eficaz.
¿Es la regularización tributaria una causa de levantamiento de la pena?
Authors: Grigoras Ioana Andreea
Published: January 2023

El apartado cuarto del artículo 305 de nuestro Código Penal establece una particular y controvertida cláusula que permite que los sujetos que han cometido un delito fiscal queden exentos de pena si regularizan su situación con la Hacienda Pública reconociendo y pagando la deuda tributaria que tienen pendiente, antes de que la Administración, el Ministerio Fiscal o el Juez de Instrucción notifique el inicio de actuaciones destinadas a averiguar la existencia de la misma. El objetivo de este trabajo es abordar, desde una perspectiva dogmática, el estudio de la naturaleza jurídica y ubicación sistemática de la regularización tributaria. Se trata de dos cuestiones ampliamente debatidas por la Doctrina, sobre las que se han formulado múltiples interpretaciones, que condicionan de forma notable la exégesis del artículo 305.4 del Código Penal, así como los efectos de dicho precepto.
Las empresas del sector público empresarial responsables penalmente
Authors: Baucells Lladós Joan
Published: January 2023

Identificar como ratio legis de la reforma de 2015 la voluntad de exigir responsabilidad penal a las sociedades públicas mercantiles obliga a realizar una interpretación restrictiva de la exclusión penal de los entes públicos empresariales planteada por el art. 31 quinquies. A partir de ella, el concepto administrativo de “potestades públicas” y el comunitario de “servicios de interés general” permiten avanzar en un concepto penal relativamente autónomo sobre el cual fundamentar el trato discriminatorio entre las diversas entidades del sector público institucional. Así, el ejercicio de “potestades administrativas” permitirá delimitar los entes a quienes el apartado 1 del art. 31 quinquies excluye de responsabilidad penal. Por otro lado, el concepto comunitario de “servicio de interés general” permitirá excluir del régimen de responsabilidad limitada a aquellas sociedades mercantiles públicas que sólo desarrollan actividades económicas, quienes quedarían relegadas al régimen general de RPPJ.
Redistribución de la riqueza y delito tributario
Authors: De la Cuesta Aguado Paz Mercedes
Published: January 2023

Aceptando que la estructura típica del art. 305.1 CP no se ajusta al paradigma de los delitos de dominio, se sugiere convertir la finalidad de redistribución de la riqueza propia de los sistemas tributarios de los Estados democráticos y sociales –como el que diseña nuestra Constitución- en el referente valorativo que cumpla las funciones asignadas al bien jurídico protegido. Esta razón legitimante permite configurar el delito contenido en el art. 305.1 CP como un delito de infracción de deber, en el que la realización de la conducta típica (defraudar en sus distintas modalidades) cumple el tipo sin que sea necesario probar el perjuicio para la Hacienda Pública (como resultado naturalístico) y permite explicar la introducción de un límite mínimo a la cuantía defraudada y las atenuantes y agravantes específicas por razón de la cuantía. Además, esta razón legitimante también sirve para limitar el Ius puniendi, con lo que se superarían las objeciones teóricas a los delitos de infracción de deber en relación con el delito tributario.
Los sondeos electorales como problema de desinformación ¿Una verdad a medias? Estudio de caso sobre las Elecciones Autonómicas de la Comunidad de Madrid del 4 de Mayo de 2021
Authors: López Paz Laura
Published: January 2023

Los sondeos electorales sirven para medir el interés social que la opinión pública procesa hacia aquellos que nos gobiernan o aspiran a hacerlo por lo que analizar cómo estos se han utilizado en las Elecciones Autonómicas de la Comunidad de Madrid del 4 de mayo de 2021 tiene por objetivo revisar el uso que se hizo de los mismos y descubrir si pueden llegar a considerarse como un problema de desinformación para la ciudadanía.
Modificando el pasado y el presente para manipular el futuro: herramientas para combatir la alteración consciente del discurso histórico y fáctico con fines espurios
Authors: Pinto Tortosa Antonio Jesús , Arsuaga Méndez Adán , García-Delgado Giménez Belén , Vilches Fuentes Gerardo
Published: January 2023

El desarrollo de las nuevas tecnologías de la información y la comunicación (TICs) ha conllevado una transformación absoluta del panorama mediático global. De resultas de ello, día tras día y cada vez con mayor frecuencia hemos de enfrentarnos a una avalancha de noticias, a través de medios convencionales y de medios novedosos, que complican el proceso de información del individuo y de la sociedad respecto a la realidad que les rodea. En definitiva, estamos expuestos a un volumen de datos cada vez mayor, pero carecemos de las herramientas precisas para procesarlos y extraer la información veraz a partir de ellos. Incorporando la perspectiva filosófica, psicológica y pedagógica, entendemos que la capacidad de juicio crítico incluye la habilidad para argumentar análisis, emitir juicios o realizar inferencias. Las tres capacidades resultan fundamentales cuando leemos información y noticias sobre el pasado reciente, o sobre nuestro contexto social en general: en la medida en que analizamos una noticia estamos realizando inferencias, a través de deducciones, inducciones o hipótesis; emitimos juicios, evaluando la información; y analizamos discursos.
El fenómeno de la desinformación como amenaza a los sistemas democráticos y la complejidad de su tratamiento
Authors: Sentí Navarro Carla
Published: January 2023

La era de la información viene de la mano, paradójicamente, de unos niveles alarmantes de desinformación a nivel global. El fenómeno de la desinformación es incesante y de gran calado, y afecta no sólo a todos ámbitos de la vida social, sino también a la funcionalidad de los sistemas democráticos. Y ello porque las respuestas que hay para combatir la desinformación tienden a limitar unas libertades esenciales para nuestros sistemas democráticos – la libertad de expresión y de información – con lo que se plantean serios retos para su tratamiento. El objetivo de este artículo es situar el conflicto en el contexto actual, haciendo una revisión de algunas respuestas que se han ido planteando para combatir la enorme cantidad de información no veraz que circula por el mundo y destacar los riesgos que estas técnicas conllevan.
POLARIZACIÓN POLÍTICA, POPULISMO Y DISCURSOS ANTAGÓNICOS EN AMÉRICA LATINA: ANÁLISIS DE LOS DEBATES PRESIDENCIALES DE CHILE (2021), COLOMBIA (2022) Y BRASIL (2022)
Authors: Mila Arturo , Yasuhiro Koike , Soengas Pérez José , Lara-Aguiar Jhonatan Andrés
Published: January 2023

La política latinoamericana se ha caracterizado recientemente por el surgimiento de liderazgos populistas radicales de izquierda y derecha, lo cual ha acentuado la polarización política en el continente. Desde un análisis discursivo multidimensional, el presente analiza los últimos debates presidenciales de Brasil, Chile y Colombia, para identificar cualidades del populismo radical y la construcción de la izquierda y la derecha en el continente. Las cualidades del populismo radical destacan en Petro (izquierda), Lula (izquierda) y Bolsonaro (derecha), mientras que el resto se inserta en un esquema político partidista tradicional y, aunque puedan tener cualidades carismáticas, no destacan como líderes outsider y son asociados a movimientos políticos previos (Kast al piñerismo y Gutiérrez al uribismo). Existen dos facetas en la construcción del discurso de los candidatos: una asociada al carisma y a la construcción del ideario del pueblo y otra que habitualmente confronta a sus adversarios políticos, más que generar propuestas.
Migración internacional de retiro y urnas: elecciones municipales españolas de 2019
Authors: Durán Muñoz Rafael
Published: January 2023

El fenómeno gerontomigratorio es una realidad nacional cuya concreción demográfica a nivel local puede incidir en los resultados de los comicios en los que tienen derecho de sufragio. Este artículo aborda el compromiso cívico de los gerontoinmigrantes de retiro y analiza los factores (des)movilizadores de su voto, siendo las últimas elecciones municipales celebradas en España, de 2019, el caso de estudio. Aparte de los correspondientes datos facilitados por el Instituto Nacional de Estadística y por el Ministerio del Interior, la investigación se nutre de los resultados de una encuesta multidisciplinar realizada durante 2020. Los gerontoinmigrantes de retiro se comportan políticamente en términos similares a como lo hacen los mayores en general. Al analizar los factores con capacidad explicativa del voto frente a la abstención, el Brexit ha aflorado como un fenómeno que afecta y diferencia a los británicos.