bluuebunny/crossref_metadata_2025 huggingface dataset:
DIAGNÓSTICO DEL CAPITAL INSTRUMENTAL DE AREQUIPA COMO CIUDAD EMERGENTE DEL CONOCIMIENTO, 2008 – 2018
Authors: Larrea Glenn Roberto Arce , Mejía Wendy Anne Ugarte , Ninacondor Carlos Pedro Vera , Huayhua Graciel Anayka Bailon , Cotacallapa Carol Rudh Huamani , Callo Leidy Fiorela Rodrigo , Pacheco Estephany Yrasely Ramos , Pacheco Angela Daniela Portugal
Published: July 2024

El objetivo del artículo es brindar el diagnóstico del Capital Instrumental de Arequipa afianzado en el perfil cuantitativo y cualitativo de la ciudad; el estudio basa su análisis en las dimensiones de capital instrumental tangible e intangible de la ciudad de Arequipa; galardonada como ciudad emergente del conocimiento. El aporte se evidencia de  dos formas: divide el capital instrumental en dimensiones interdependientes que se adaptan al contexto  peruano (tanto en el ámbito tangible como en el ámbito intangible) y brinda una escala de clasificación a las dimensiones del capital instrumental, logrando así un diagnóstico de la capacidad tangible e intangible de la ciudad. Para ello, se utilizó la metodología del Sistema de Capitales, la cual asegura la calidad e innovación de los procesos en la Administración del Conocimiento (AC). Los resultados muestran la necesidad de potenciar ciertas dimensiones como: liderazgo empresarial e investigación y desarrollo, en el aspecto intangible para brindar un valor agregado a todas las actividades que en ella se desempeñan. Asimismo, en el aspecto tangible, es necesario implementar mejoras en la conectividad e informatización de la ciudad, el sector agrícola y los espacios de intercambio cultural y de negocios.DOI: 10.18226/23190639.v9n3.09 Glenn Roberto Arce Larrea*, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Wendy Anne Ugarte Mejía, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Carlos Pedro Vera Ninacondor, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Graciel Anayka Bailon Huayhua, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Carol Rudh Huamani Cotacallapa, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Leidy Fiorela Rodrigo Callo, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Estephany Yrasely Ramos Pacheco, UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Angela Daniela Portugal Pacheco UNSA - Universidad Nacional de San Agustín de Arequipa, Peru. Submetido: Janeiro 2022Aceito: Abril 22022 *Contato para Correspondênciaglenn@unsa.edu.pe
q−Relativistic wave equation of the form i∂^q·ψq + mψ_0 = Eψ
Authors: Jaramillo-Quiceno Julio Cesar
Published: July 2024

In this paper we introduce a q relativistic wave equation of the form i∂^q·ψq + mψ_0 = Eψ. We present the q-spinorial solutions using the method of separated variables in the q-relativistic wave equation. Some comments are mentioned at the end of the paper.
Síndrome de Boerhaave concomitante a neumonía por COVID-19: manejo con terapia combinada. Reporte de caso
Authors: Esteban-Mojica Olman , Prada-Rivera Mario Fernando , Peña-Delgado Mitzi Yurani , Sequea-Meneses David Mateo , Quintero Diana Clemencia
Published: July 2024

El síndrome de Boerhaave es una patología rara que conlleva una mortalidad que ronda entre el 30-50 %. Consiste en un desgarro transmural espontáneo del esófago secundario a un aumento súbito en la presión esofágica intraluminal, que en sólo tres reportes de la literatura ha estado asociado causalmente a infección por SARS-CoV-2. Se presenta el caso de un paciente masculino de 68 años con cuadro clínico de inicio súbito consistente en abundantes episodios de emesis que posteriormente presenta deterioro respiratorio, asociado a enfisema subcutáneo en hemitórax derecho. Se documenta neumonía por SARS-CoV-2 y Síndrome de Boerhaave, por lo que es llevado a esofagorrafia y dado evolución postquirúrgica tórpida, se indica terapia de vacío endoluminal con progreso favorable a los 4 meses de seguimiento. Esta patología representa un reto diagnóstico dado su inespecífica presentación clínica, por lo que el retraso en el reconocimiento impactará directamente en el abordaje terapéutico y pronóstico.
Hepatitis autoinmune seronegativa: reporte de un caso
Authors: Gomez-Pastrana Juan Carlos
Published: July 2024

La hepatitis autoinmune es una enfermedad inflamatoria y necrótica del hígado, crónica e infrecuente caracterizada por la presencia de autoanticuerpos. La incidencia y la prevalencia de esta varía entre continentes, incluso entre países, con una prevalencia a nivel mundial de 3 por cada 100 000 en la población adulta, siendo predominante en mujeres. El diagnóstico se basa en la medición de autoanticuerpos, como los autoanticuerpos antinucleares, anticuerpos antimúsculo liso y anticuerpos antimicrosomales de hígado y riñón. El 10 % no presentan anticuerpos denominándose hepatitis autoinmune seronegativa. A continuación, se presenta el caso de una mujer de 63 años, hipertensa, con cuadro de un año de evolución de astenia, acolia e ictericia mucocutánea y laboratorio con hipertransaminemia e hiperbilirrubinemia directa. Se diagnosticó enfermedad hepática crónica mediante biopsia y posteriormente hepatitis autoinmune ante negatividad de anticuerpos, finalmente se trató con corticoides y azatioprina, con resolución del cuadro.
Asociación entre la movilidad articular, composición corporal y actividad física autopercibida en universitarios de Bogotá, Colombia. 2023
Authors: Cardozo Luis Alberto , Cuellar-Peña Andrés Felipe , Reina-Monroy Javier Leonardo , Castillo-Daza Carlos Alberto , Masso-Calderón Ana María
Published: July 2024

Introducción: la movilidad articular es una cualidad física que disminuye con el avance de la edad si no se entrena de manera sistemática. Desempeña un papel crucial en la realización eficiente de las actividades cotidianas, desde acciones sencillas como caminar hasta movimientos más complejos como realizar actividad física. Objetivo: analizar la relación entre los niveles de movilidad articular, la composición corporal y la actividad física autopercibida en estudiantes universitarios. Metodología: diseño transversal con un enfoque descriptivo-correlacional, y se implementó un muestreo por conveniencia. Para evaluar la movilidad articular se utilizó la batería de pruebas flexitest, la composición corporal se evaluó a través de bioimpedancia tetrapolar y se registró la actividad física autopercibida mediante la “escala subjetiva de actividad física”. Resultados: participaron en el estudio 72 sujetos universitarios con una edad promedio de 22,4 ± 3,74 años. Se encontró que las mujeres presentan niveles de movilidad articular superiores a los hombres, 55,50 puntos vs. 48,92, respectivamente (p = 0,003). Además, se observó una mayor frecuencia en la categoría “alta” en el nivel de movilidad articular en los participantes (45,2 %). No se encontró una asociación significativa entre los niveles de movilidad articular, la composición corporal y la actividad física (p > 0,05). Más del 56 % de los participantes no cumplen con las recomendaciones mínimas de actividad física a la semana recomendadas. Conclusiones: los niveles de movilidad articular y composición corporal varía según el sexo, se deben diseñar estrategias institucionales para la promoción de la actividad física.
Double wavefront reversal during six-wave interaction on Kerr nonlinearity in a waveguide with infinitely conducting surfaces
Authors: Ivakhnik Valery V. , Kapizov Darkhan R. , Nikonov Vladimir I.
Published: July 2024

Background. Generation of a wave with a double reversed wavefront in multimode waveguides increases the efficiency of six-wave radiation converters and expands the possibilities of its use in adaptive optics problems and the conversion of complex spatially inhomogeneous waves.
Aim. The quality of double wavefront reversal during six-wave interaction in a waveguide with infinitely conducting surfaces with Kerr nonlinearity is analyzed for the ratio of the wave numbers of the pump waves equal to 2 and 0,5, and the condition that one of the pump waves excites the zero mode of the waveguide, and the amplitude distribution of the other pump wave excites the edges of the waveguide are described by a Gaussian function.
Methods. The influence of pump wave parameters on the half-width and contrast of the amplitude modulus of the object wave was studied using numerical methods. A wave from a point source located on the front face of the waveguide was used as a signal wave.
Results. The dependences of the half-width and contrast of the amplitude modulus of the object wave on the ratio between the width of the waveguide and the width of the Gaussian pump wave are obtained.
Conclusion. It is shown that the maximum change in the characteristics of a wave with a double reversed wavefront is observed when the width of the Gaussian pump waves changes in the range from 0,3 to 2 half-widths of the waveguide.
Parametrical synthesis of various radio devices with the set quantity of identical cascades of type «the nonlinear part – the resistive two-port network»
Authors: Golovkov Alexander A.
Published: July 2024

Background. Presence of possibility of analytical definition of a part of parametres of various radio devices, optimum by criterion of maintenance of preset values of modules and phases of transfer functions on necessary quantity of frequencies, considerably reduces time of numerical optimisation of other part of parametres by criterion of formation demanded PFC and FFC in a strip of frequencies. Till now such problems dared concerning radio devices only with one cascade of type «a nonlinear part – the coordination the device» or «the coordination the device – a nonlinear part». In quality согласующего devices were used the jet, resistive, complex or mixed two-port networks. The problem of multicascade radio devices with jet two-port networks is solved also. Change of basis for the coordination two-port networks and a place of inclusion of a nonlinear part leads to change of area of a physical realizability.
Aim. Working out of algorithms of parametrical synthesis of radio devices with any quantity of identical and unequal cascades of type «a nonlinear part -the coordination the resistive two-port network» by criterion of maintenance of the set frequency characteristics. Nonlinear parts are presented in the form of a nonlinear element and parallel either consecutive on a current or pressure of a feedback.
Methods. The theory of two-port networks, matrix algebra, a decomposition method, a method of synthesis of actuation devices microwave, numerical methods of optimisation.
Results. In interests of achievement of the specified purpose systems of the algebraic equations are generated and solved. Models of optimum two-port networks in the form of mathematical expressions for definition of interrelations between elements of their classical matrix of transfer and for search of dependences of resistance of two-poles from frequency are received. It is shown, that at certain parities between quantity of cascades and values of resistance of a source of a signal and loading of the one-cascade radio device frequency characteristics of one-cascade and multicascade radio devices appear identical or similar. Such schemes are named by equivalent.
Conclusion. The comparative analysis of theoretical results (PFC and FFC radio devices, value of parametres), received by mathematical modelling in system MathCad, and the experimental results received by circuit engineering modelling in systems OrCad and MicroCap, shows their satisfactory coincidence.
Convergence region size research of television signal superposition iteration method for measurement machine vision system
Authors: Diyazitdinov Rinat R.
Published: July 2024

Background. Image processing is used in machine vision measurement systems, which are widely used in industrial applications. One of the important tasks in processing is image superposition. Registration methods must fulfill two basic requirements: satisfactory registration quality and practical processing time. One of the methods that meets these requirements is iterative superposition.
Aim. The aim is to study the size of the area (region of convergence) for the values of the parameters of the initial approximation, which ensures satisfactory superposition. The size of the region determines the performance of the iterative algorithm.
Methods. The size of the region of convergence was determined experimentally: correlation analysis and statistical simulation.
Results. Experiments have shown if a sampling step is no more than 1/10 of the size of the image fragment, then the probability of correct registration is almost equal to one. If this threshold is exceeded, then the probability decreases.
Conclusion. The size of the region of convergence of the iterative image registration method has been established. It is possible to design processing algorithms and predict processing time by obtaining results. The superposition method was introduced into a machine vision system to recognize contact wire clamps on the railway. Image superposition in this system is carried out in real time.
Antenna array of waveguide horns with an E-plane aperture, as well as horns with an aperture in the E- and H-planes
Authors: Pasternak Yuri G. , Pendyurin Vladimir A. , Proskurin Dmitry K. , Safonov Kirill S.
Published: July 2024

Background. Currently, in connection with the conduct of a special military operation, the issue of the availability of inexpensive mobile terminals for high-speed satellite communications of domestic production is very relevant, as well as due to the large extent of the territories of our country, there are a number of areas where cellular communication is absent, for example, the Taiga, the Arctic, the territory of the Arctic Ocean, etc. Therefore, the only possible connection in these territories is satellite communication.
Aim. Development of a linear equidistant antenna array with equal amplitude and common-mode excitation for a mobile satellite communication terminal.
Methods. The antenna array was designed from the open ends of waveguides with a cross section of 19 × 11 mm with air filling. Adjacent pairs of radiating waveguides are powered by an E-planar divider: the waveguide is divided in half in height by a thin metal diaphragm, wave reflections from which are insignificant; further, in each half of the power divider, height-separated right and left turns and smooth transitions in the E-plane are implemented – an extension from 5,25 mm to 11 mm.
Results. An antenna array with a period of 19,5 mm has been developed. Overall dimensions: opening width – 624 mm, height – 12 mm, depth – 118 mm. A feature of the antenna array design is the use of smooth asymmetric transitions in the E-plane according to the exponential law; in the opening of the headlights, waveguide asymmetric horns alternate, with a period equal to 4 values of the width of the waveguides, taking into account the width of their narrow walls, expanding in the upper (2 adjacent radiators) and lower (next 2 radiators) directions.
Conclusion. The advantage of using an approach to the construction of linear antenna arrays powered by multichannel power dividers is the ability to minimize the depth of the antenna system. The main disadvantages are the constructive and technological complexity of power dividers and significant power losses with a large number of channels. Possible manufacturing technologies of the developed phased array: 1. Stamping of polystyrene of the inner part of the power divider and emitters. Next, polishing, copper spraying and electroplating with a layer of copper. 2. Printing on a 3D polystyrene printer, polishing, copper spraying and copper electroplating. 3. Manufacture of a power divider using SIW technology based on standard microwave laminates. The use of metallized through holes for matching power dividers. Antenna elements and coaxial waveguide junctions are made by stamping from polystyrene, or printing on a 3D printer from polystyrene, then polishing, spraying a layer of copper and electroplating with a layer of copper. 4. Metal stamping of the power divider, emitters and coaxial waveguide junctions (2 parts). The dielectric insert can be printed on a 3D printer made of polystyrene.
Caracterização dos pacientes atendidos com traumatismo cranioencefálico num hospital público de Minas Gerais
Authors: Siqueira Jânio Eduardo , Dutra Cíntia Machado , Ferreira Lúcia Aparecida
Published: July 2024

Objetivo: descrever as características sociodemográficas dos pacientes atendidos com traumatismo cranioencefálico em um hospital público. Método: estudo descritivo, transversal, de abordagem quantitativa, com o levantamento de dados secundários obtidos no Departamento de Informática do Sistema Único de Saúde, período de 2022 e 2023, consideradas as seguintes variáveis de preenchimento obrigatório do Sistema de Informações Hospitalares: sexo, faixa etária, cor/raça e óbitos. Os dados foram analisados por meio de estatística descritiva. Resultados: foram registradas 464 internações por traumatismo cranioencefálico, sendo a maior frequência no sexo masculino, em pacientes que se declaram de cor branca e com faixa etária de 40 a 69 anos. Do total de 64 óbitos por traumatismo cranioencefálico, houve maior frequência também no sexo masculino, em pacientes de cor parda e com idade 40 a 69 anos. Conclusão: a compreensão das características sociodemográficas dos pacientes com traumatismo cranioencefálico pode contribuir para a melhoria dos protocolos de tratamento e prevenção, e aponta a necessidade de abordagens personalizadas que considerem as diversas facetas do perfil sociodemográfico dos indivíduos afetados.
Análise da acessibilidade potencial à rede de atenção primária em um município do interior mineiro
Authors: Chirieleison Fernandes Januário , Vicente Ferreira Ricardo , Abreu Manuela de , Silva Caixeta Daniel Edson , Oliveira Carvalho Célia Maria , Santos Álvaro da Silva
Published: July 2024

Objetivo: avaliar a distribuição das Unidades Básicas de Saúde e a acessibilidade potencial à Atenção Primária à Saúde das populações na área urbana de um município mineiro. Método: Estudo quantitativo realizado no primeiro trimestre de 2024 na cidade de Uberaba, Minas Gerais, utilizando dados preliminares do Censo de 2022, do Instituto Brasileiro de Geografia e Estatística, e dados de localização das Unidades Básicas de Saúde obtidos junto à Secretaria Municipal de Saúde. Baseou-se no método two-step Floating Catchment Area method para calcular a acessibilidade potencial da população à rede de Atenção Primária. As informações geradas foram analisadas por meio de mapas temáticos e estatísticas descritivas. Resultados: a cidade de Uberaba possui uma população de 337.836 habitantes, das quais 310.271 concentram-se em áreas urbanas com alta densidade, e dispõe de 27 Unidades Básicas de Saúde na área urbana. A distribuição populacional: 732 setores censitários caracterizados por alta densidade de edificações, sendo que 48% concentra-se entre 372 a 721 habitantes, 31% entre 214 a 372, e 7% de 721 a 1265. Ao considerar o raio de influência de 1.000m a partir de cada UBS, observa-se que, aproximadamente, 15 (56%) cobrem uma população residente potencial de 6.400 e 12.500 pessoas, enquanto apenas duas (7%) alcançam entre 3.300 e 6.400. Por sua vez, 10 unidades (38%) cobrem uma população residente potencial de 12.500 a 18.700. Conclusão: a distribuição das Unidades Básicas de Saúde na acessibilidade potencial é adequada e acompanham a distribuição populacional.
PENERIMAAN PANELIS TERHADAP ES KRIM ALPUKAT
Authors: Anwar Chairil , Irhami Irhami , Aprita Ika Rezvani , Irmayanti Irmayanti , Kemalawaty Mulla
Published: July 2024

Buah alpukat memiliki daging buah dengan warna yang menarik, tidak manis namun beraroma khas, serta memiliki kandungan lemak yang tinggi. Kandungan lemak tinggi ini menjadikan alpukat berpotensi sebagai krim nabati dalam basis pembuatan es krim sehingga berfungsi memberikan aroma dan kontribusi rasa, serta untuk memberi tekstur halus pada es krim. Tujuan penelitian ini adalah untuk mengetahui pengaruh penambahan buah alpukat (Persea americana Mill) sebagai krim nabati terhadap kualitas organoleptik es krim. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan konsentrasi penambahan buah alpukat yang terdiri 4 (empat) taraf perlakuan, yaitu A=20%, B=40%, C=60%, dan D=80%. Konsentrasi buah alpukat berpengaruh sangat nyata (P<0,01) terhadap nilai organoleptik warna dan rasa namun berpengaruh tidak nyata (P>0,05) terhadap nilai organoleptik aroma dan tekstur. Es krim dengan kualitas organoleptik terbaik diperoleh pada perlakuan penambahan alpukat pada konsentrasi 40% dengan karakteristik: warna 4,10 (suka); rasa 4,00 (suka); aroma 3,65 (suka); dan tekstur 3,46 (agak suka).
ESTIMASI ENERGI DAN PRODUK SAMPING FERMENTASI RANSUM BERBASIS INDEKS SINKRONISASI PROTEIN-ENERGI BERDASARKAN STOIKIOMETRI VOLATILE FATTY ACIDs: KAJIAN IN VITRO
Authors: Syamsi Afduha Nurus , Widodo Hermawan Setyo , Candrasari Dewi Puspita , Subagyo Yusuf , Ifani Merryafinola , Safitri Lis
Published: July 2024

Ransum berbasis indeks sinkronisasi protein-energi (SPE) merupakan pengembangan nutrisi ruminansia yang ditujukan pada optimalisasi sintesis protein mikroba (SPM). Optimalisasi SPM diupayakan dengan sinkronisasi ketersediaan ammonia dan energi melalui indeks antara 0-1. Semakin simultanya kedua senyawa tersebut diharapkan mampu meningkatkan kecernaan, produksi volatile fatty acid (VFA), dan estimasi energi yang dihasilkan. Tujuan penelitian ini adalah untuk menghitung estimasi produksi energi dan produk samping pada ransum berbasis indeks SPE melalui stoikiometri pembentukan VFA. Materi penelitian adalah cairan rumen kambing jawa randu yang di ambil sesaat setelah ternak dipotong. Penelitian menggunakan Rancangan acak lengkap (RAL) dengan 5 perlakuan (Indeks ransum 0,55; 0,6; 0,65; dan 0,7) dan 4 ulangan. Estimasi energi dan produk hasil samping fermentasi dihitung berdasarkan stoikiometri pembentukan VFA. Data dianalisis dengan analisis variansi. Hasil menunjukkan bahwa ransum berbasis indeks SPE tidak berpengaruh nyata (P>0,05) terhadap semua variablel (estimasi energi reaktan, total produksi energi, efisiensi produksi energi, methane, energi terbuang, hidrogen, karbon dioksida, dan air). Disisi lain, penelitian menunjukkan bahwa ransum berbasis indeks SPE menghasilkan estimasi efisiensi produksi energi yang rendah, karena estimasi produksi methane yang tinggi. Hal ini disebabkan karena tingginya proporsi serat ransum, pembentukan asetat, serta H2 dan CO2.
PENGARUH FAKTOR SOSIAL EKONOMI TERHADAP MINAT MASYARAKAT BETERNAK SAPI BALI DI KECAMATAN NAPABALANO KABUPATEN MUNA
Authors: Abadi Musram , Indi Amiluddin , Firmanto Firmanto
Published: July 2024

Penelitian ini bertujuan untuk menganalisis pengaruh faktor sosial ekonomi terhadap minat masyarakat beternak sapi Bali di Kecamatan Napabalano Kabupaten Muna. Penelitian ini menggunakan metode survei dengan penentuan lokasi secara sengaja (purposive sampling), dengan pertimbangan bahwa Kecamatan Napabalano Kabupaten Muna merupakan daerah dengan populasi sapi Bali terbanyak. Analisis data yang digunakan adalah analisis regresi linier berganda dengan variabel yang diamati adalah aspek sosial (faktor masyarakat, status sosial) dan aspek ekonomi (pendapatan peternak, sumber pendapatan, dan pemasaran). Nilai F hitung sebesar 5,863 lebih besar dari nilai F tabel (2,262). Nilai koefisien determinan (R2) sebesar 0,3999 dan nilai signifikansi sebesar 0,000 (<0,05). Maka dapat disimpulkan bahwa masyarakat di Kecamatan Napabalano Kabupaten Muna dipengaruhi oleh faktor sosial ekonomi dalam beternak sapi Bali.
DIFFICULTIES IN DIAGNOSING COMPLICATIONS OF DUODENAL DIVERTICULAR DISEASE
Authors: YAROVENKO GALINA V. ,   Samara State Medical University, KATORKIN SERGEY E. , KOLTSOV ANTON E. , AKANIN MAKSIM S. ,   Samara State Medical University,   Samara State Medical University,   Samara State Medical University
Published: July 2024

Abstract. Introduction. Duodenal diverticulum is a hernia‒like protrusion of the duodenal wall. In terms of prevalence, this disease ranks second among all diverticula of the gastrointestinal tract after colonic diverticula. Aim. To substantiate the difficulty of diagnosing duodenal diverticulum perforation, based on a clinical case. Materials and Methods. A clinical case dated December 2021 of successful diagnostics and treatment of duodenal diverticulum perforation in female patient A. aged 68 is presented, based on the practice of the surgeons of the Surgery Unit in the Clinic of Hospital Surgery of Samara State Medical University. A set of laboratory investigations was performed, such as clinical blood analysis, biochemical blood analysis, coagulation profile, clinical urine analysis, and blood tests for HIV, viral hepatitis, and syphilis. Instrumental diagnostic methods were used, such as ultrasound (Aloka SSD 1700 (Japan)), CT (Revolution EVO (Russia)) of abdominal organs, review radiography, and Napalkov test. Results and Discussion. Laboratory and instrumental diagnostics, such as ultrasound and survey radiography, and primary laparotomy turned out to be insufficient for correct diagnosis and reasonable treatment. Napalkov test was performed, which revealed the contrast agent flow into retroperitoneum. The patient underwent relaparotomy, during which the duodenal diverticulum perforation by a foreign body (a fragment of a laurel leaf) was found. Conclusions. The case presented is an example of timely diagnosis of duodenal diverticulum perforation. The surgeons’ experience allowed them to suspect perforation in a short time, which helped avoid serious complications and contributed to the patient’s recovery. With timely diagnosis of such a rare and grave complication as duodenal diverticulum perforation, its clinical cure is justified.
РАСПРОСТРАНЕННОСТЬ И ЗАБОЛЕВАЕМОСТЬ РАССЕЯННОГО СКЛЕРОЗА В ГОРОДЕ БАКУ (РЕСПУБЛИКА АЗЕРБАЙДЖАН)
Authors: GULIYEVA AYGUN I. ,   Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev
Published: July 2024

Abstract. Introduction. Multiple sclerosis is a common neurological disease that causes inflammation and degeneration in the central nervous system. Globally, there is a growing trend in the prevalence of multiple sclerosis, with various incidences ranging from stable to increasing. Aim. To determine the prevalence and incidence of multiple sclerosis in the city of Baku. Materials and Methods. The study was conducted based on the State program. A total of 535 patients were diagnosed with multiple sclerosis between 2013 and 2019. Of these, 70.1% were female and 29.9% were male. The data was processed by the Statistica for Windows 10 software package using absolute and relative indicators. Results and Discussion. The overall prevalence of multiple sclerosis was 23.3 cases per 100,000 population by 2019. At the same time, the indicator increased in both women and men (from 12.7 to 32.5 in women and from 7.6 to 14.0 in men, respectively). Patients in the age group from 20 to 40 years prevailed over the rest. In the group under 19 years of age, men predominated, and starting from 20 years of age, women predominated. The prevalence of multiple sclerosis among residents of the central areas of the city was higher than in coastal areas, their ratio was 1.4:1.0. The incidence rate remained relatively stable over the study period (2.1–2.9/100,000), while the rate increased from 2.7 to 3.7 in women and decreased from 2.1 to 0.9 in men. Conclusions. The prevalence of multiple sclerosis in the city of Baku showed an increasing trend, with the city being classified as a medium-risk zone for MS. The indicator prevailed among women and residents of the central regions of the city. The incidence remained stable due to an increase in the rate among women with a parallel decrease among men. The incidence of MS prevailed in the age range from 20 to 40 years.
RISK FACTORS OF RESISTANCE IN JUVENILE MYOCLONIC EPILEPSY
Authors: GAMIROVA RIMMA G. ,   Kazan Federal University, SOKOLOVA ALINA A. , GOROBETS ELENA A. , GAMIROVA REGINA R. ,   Kazan Federal University,   Kazan Federal University,   Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, Japan
Published: July 2024

Abstract. Introduction. Juvenile myoclonic epilepsy is the most common form of genetic generalized epilepsy, which is included in the group of idiopathic generalized epilepsies. The etiology of drug-resistant forms of juvenile myoclonic epilepsy, which represent a serious clinical problem, is currently a controversial issue. Aim. To reveal the most significant risk factors of resistance in juvenile myoclonic epilepsy. Materials and Methods. The observational retrospective study included 56 patients, 46 (82%) women and 10 (18%) men. Inclusion criteria: patients diagnosed with juvenile myoclonic epilepsy based on the criteria of the International League Against Epilepsy, treatment for at least 2 years. The type and frequency of epileptic seizures, the onset and course of the disease, concomitant diseases, family history, all available results of 1-2 hours video electroencephalographic monitoring with sleep, and magnetic resonance imaging results were analyzed. Depending on the treatment effect, all patients were divided into two groups: 1 – without seizures, 2 – with seizures. Lack of complete seizure control for at least 2 years was considered intractable epilepsy. Risk ratios as outcomes for dichotomous variables in two compared groups for various characteristics and their confidence intervals were calculated using the Review Manager program (v5.3). Differences were considered significant at P<0.05. Results and Discussion. As a result, there were obtained data on the resistance of juvenile myoclonic epilepsy depending on the age of disease onset, the type of epileptic seizures, changes in the electroencephalogram, and the type of antiepileptic treatment. Conclusions. The most significant risk factors of resistance in juvenile myoclonic epilepsy have been identified: frequent generalized tonic-clonic seizures (more than 5 times a year) accompanying the basic disease, depression, anxiety, and lack of response to the treatment with valproic acid. At the same time, non-compliance, sleep disturbances, consumption of alcohol and energy drinks during therapy are factors that can be controlled during the physician’s individual work with the patient aimed at the explanation and prevention of risks in treatment.
ACQUIRED HEMOPHILIA A IN THE MODERN MEDICAL REALITY: PRACTICAL CLINICAL EXPERIENCE
Authors: ADIEVA ADELYA A. ,   Kazan State Medical University, IVANOVA ELENA V. , POLOVINKINA EKATERINA N. , BELOUSOVA ELENA N. , KOSTERINA ANNA V. ,   Kazan State Medical University,   Republican Clinical Hospital, Kazan,   Kazan State Medical University,   Kazan State Medical University
Published: July 2024

Abstract. Introduction. Acquired hemophilia A is a rare form of severe coagulopathy with an autoimmune mechanism of development. It occurs due to the formation of circulating inhibitory factor VIII (FVIII) antibodies, which leads to impaired activation of factor X and the occurrence of spontaneous bleeding in patients without previous hemostasis system pathology. In about a half of the cases, FVIII autoantibodies appear in patients without any comorbidities. It should be noted that the average age of patients was 74 years at the time of diagnosis. However, the occurrence of the disease in young women is rare and may be associated with pregnancy and childbirth. Given the rarity of this disease, the management of these patients is a challenging clinical problem. Aim. To describe a clinical case of diagnosis and treatment of a patient with the inhibitor form of acquired hemophilia A (AHA). Materials and Methods. A 38–year–old female patient had acute hemorrhagic syndrome of the hematoma type, manifested by large hematomas in different areas of the body. During the patient’s stay in the hospital, standard lab tests were made, the test results were evaluated over time, and instrumental diagnostics was performed. Results and Discussion. The typical hematoma type of bleeding detected during diagnosing, prolongation of coagulation parameters, presence of factor VIII inhibitor (605 BU), and a decrease in factor VIII level down to 0.5%) verified the AHA diagnosis. Methods of substitution, immunosuppressive therapy, and monoclonal antibodies were successfully used to treat AHA in this patient. The patient is followed up by a hematologist at the place of residence. Hematomas did not recur. Conclusions. This clinical observation demonstrates the peculiarities of the course, diagnostic algorithm, and management of patients with AHA without any concomitant pathology, with a history of only prolonged postpartum uterine bleeding, and with no autoimmune or malignant diseases.
Pengaruh Media Pembelajaran Terhadap Kemandirian Belajar dan Keterampilan Menulis Teks Drama
Authors: Razanah Marini , Solihati Nani , Safi'i Imam
Published: July 2024

Students' ability in writing drama text is influenced by several factors that occur in learning. The purpose of the study was to determine the effect of learning media and students' independence in learning on the skills of writing drama texts of students in class XI of SMAN 21 East Jakarta. This research used experimental method. The population in this study were all students of class XI of SMAN 21 East Jakarta. The research sample was conducted using Purposive Sampling technique as many as 60 students who were divided into two groups, where 30 students learned using family movie drama media and the other 30 people learned using conventional media. The instruments used in this study are: Learning independence questionnaire and drama text writing skill test. The results showed that the use of family film drama media gave better results in the aspects of learning independence and drama text writing skills. The use of conventional media makes students learn through several stages or indirectly. The use of family film drama media is recommended in learning to write drama texts because it can provide a direct picture and increase students' learning independence and motivation
Perkembangan Bahasa Anak Perempuan Usia 3 Tahun di Desa Teumpeun
Authors: Istiqamah Istiqamah , Nurfazilah Nurfazilah , Nazlina Saskia Aulia , Ilmi Nurul , Intan Cut
Published: July 2024

Language is a human communication system that is used to understand each other with certain goals. This research aims to find out the process of language development in three year old children. The method used in this research is a descriptive method with a qualitative approach. The results of the research found that Aqila can now say 2 to 4 words such as drink milk, Dad buy snacks. By using data collection techniques in the form of observation, interviews and documentation. The results of interviews with the child's parents and observing directly his language development showed that this child experienced language development according to the level at his age, including the words mother, father, sister, brother, milk, traveling. This research can conclude that Aqila often omits several phonemes or even adds phonemes to her vocabulary. Such as changing the consonant phoneme /k/ to consonant phoneme /t/, and changing the consonant phoneme /l/ to consonant phoneme /r/.
Kemampuan Menulis Karangan Eksposisi Menggunakan Media Gambar Fotografi Siswa Kelas X MIA 2 SMAN 3 Sungai Penuh
Authors: Maiza Suci , Septia Emil
Published: July 2024

Writing skill is one of the critical linguistic aspects to be developed in language skills. One alternative to attract students' attention and motivation in the learning process is photographic image media. This research objective was to describe the writing skill of an expository essay using photographic image media in class X MIA 2 at SMAN 3 Sungai Penuh. The expository essay included structural aspects, content aspects, and linguistic aspects. The research design was quantitative research with a descriptive method. The research population consisted of 172 students of class X MIA at SMAN 3 Sungai Penuh, with a sample of 36 people. The research instruments were performance tests, observations, field notes, observation guidelines, and assessment sheets. The data collection technique in this research was giving an exposition essay writing test and documentation. The research indicated that the use of photographic image media could help students of class X MIA 2 at SMAN 3 Sungai Penuh in writing expository essays. It could be seen in the results of the exposition writing test of students who obtained a mean score of 81.25 with a percentage of 75% in the capable category.
Analisis Kandungan Logam Dan Ftalat pada Komponen Eletronik menggunakan XRF dan Py/GC-MS
Authors: Lestari Ayu Zakiyah , Maulida Nabilah
Published: July 2024

Abstrak
Perkembangan elektronik pada bidang industri mempengaruhi kehidupan sehari hari. Penggunaannnya yang berlebihan dapat meningkatkan resiko berbahaya pada penggunanya. Salah satu faktor bahaya pada komponen elektronik yang digunakan adalah terdapatnya logam dan flatat. RoHS merupakan regulasi Uni Eropa yang mengatur pembatasan penggunaan zat-zat berbahaya seperti Pb, Hg, Cd, dan Cr6+, serta PBB, PBDE, DIBP, DBP, BBP, dan DEHP dalam produk-produk elektronik dan listrik. Penelitian ini bertujuan untuk mengetahui kandungan zat-zat berbahaya yang diatur oleh RoHS pada sampel komponen elektronik. Metode yang digunakan adalah skrining awal menggunakan XRF dan penetapan kadar ftalat dengan Py/GC-MS. Hasil penelitian menunjukkan bahwa sampel tidak mengandung logam berat (Cd, Hg, Cr), DIBP, BBP, dan turunan Br. Kandungan Pb, DBP, dan DEHP yang terdeteksi memiliki konsentrasi rendah dan tidak melebihi batas maksimum penggunaan ftalat yang ditetapkan oleh RoHS, sehingga part elektronik tersebut dapat digunakan dalam produksi.
Kata kunci: elektronik, ftalat, logam, Py-GC-MS, RoHS, XRF
Abstract
The development of electronics in the industrial sector affects daily life. Its excessive use can increase the risk of harm to its users. One of the hazardous factors in the electronic components used is the presence of metals and flattates. RoHS is a European Union regulation that regulates restrictions on the use of hazardous substances such as Pb, Hg, Cd, and Cr6+, as well as PBB, PBDE, DIBP, DBP, BBP, and DEHP in electronic and electrical products. This study aims to determine the content of RoHS-regulated hazardous substances in electronic component samples. The methods used were preliminary screening using XRF and determination of phthalate levels by Py/GC-MS. The results showed that the samples did not contain heavy metals (Cd, Hg, Cr), DIBP, BBP, and Br derivatives. The detected Pb, DBP, and DEHP contents had low concentrations and did not exceed the maximum limit of phthalate use set by RoHS, so the electronic parts could be used in production.
Keywords:electronics, metals,  phthalates,  Py-GC-MS, RoHS, XRF
Pemanfaatan Serat Bambu Sebagai Bahan Tambah Campuran Beton
Authors: Mulyati  , Arman Arman , Aulia Farhan Muhammad , Alawiyah Nurfelia
Published: July 2024

Bambu merupakan tanaman penghasil serat yang dapat digunakan sebagai alternatif bahan tambah serat untuk campuran beton untuk mengatasi retak pada beton. Tujuan dari penelitian ini adalah untuk mengetahui nilai kuat tekan dan kuat tarik belah beton dari penggunaan serat bambu sebagai bahan tambah campuran beton.  Bambu yang digunakan adalah bambu petung dan bambu apus, ukuran serat panjang 20 mm dan diameter 1-2 mm, dengan persentase 1%, 2%, 3%, 4%, 5% dari berat semen.  Perencanaan campuran beton menggunakan SNI 7656-2012 untuk kuat tekan rencana 20 MPa pada umur 28 hari.  Hasil pengujian kuat tekan dan kuat tarik belah beton dari persentase penggunaan serta, untuk bambu petung diperoleh kuat tekan beton rata-rata berturut-turut sebesar 23,58 MPa, 24,69 MPa, 19,45 MPa, 17,17 MPa, 13,02 MPa, dan kuat tarik belah beton berturut-turut sebesar 2,05 MPa, 2,40 MPa, 2,06 MPa, 2,03 MPa, 2,02 MPa, sedangkan untuk bambu apus diperoleh kuat tekan beton rata-rata berturut-turut sebesar 22,56 MPa, 23,07 MPa, 15,37 MPa, 14,09 MPa, 14,07 MPa, dan kuat tarik belah beton rata-rata berturut-turut sebesar 2,15 MPa, 2,50 MPa, 2,47 MPa, 2,40 MPa, 2,30 MPa.  Penggunaan serat bambu sampai 2% pada campuran beton dapat meningkatkan kuat tekan beton, dan penggunaan serat bambu sampai 5% dapat meningkatkan kuat tarik belah beton.   Serat bambu petung menghasilkan kuat tekan beton yang lebih tinggi dari pada serat bambu apus, sedangkan serat bambu apus menghasilkan kuat tarik belah beton yang lebih tinggi dari pada serat bambu petung.
“The Arab-Latin Question”. A Review of: Brenet, J.-B. Chto znachit myslit’? Arabo-latinskij otvet [Que veut dire penser? Arabes et Latins]. М.: Ad Marginem Press, 2024, 152 pp. (Russian Translation)
Authors: Nofal Faris O. ,   RAS Institute of Philosophy
Published: July 2024

The review is devoted to the work of the French medievalist and historian Jean-Baptiste Brené (born 1972) “Que veut dire penser? Arabes et Latins” (2022), first published in Russian. The author critically examines Brené’s excursions into the history of Arab Peripatetism and proves their irrelevance to the stated topic of the book. At the same time, the reviewer demonstrates postmodernist essence of treatise main idea — the postulate about the positive openness of cognition “cosmic” phenomenon.
Combination of different drugs can enhance prevention of CIAKI through inhibition of endoplasmic reticulum stress-induced apoptotic pathway
Authors: Wang Xuan , Han Shan , Cong Hongliang
Published: July 2024

Introduction: Contrast-induced acute kidney injury(CIAKI) is an important clinical complication that occurs after the application of contrast in percutaneous coronary intervention. The pathogenesis of CIAKI is complex. Studies have shown that the cell apoptosis induced by endoplasmic reticulum stress (ERS) play an important role in the renal tubular injury of CIAKI. It was suggested that atorvastatin, probucol and alprostadil can inhibit renal tubular cell apoptosis to prevent CIAKI. However, there is no specific research about the above effect of the drug combination. Therefore, this study intends to establish the rat CIAKI model by meglumine diatrizoate and add drug intervention, to compare the influence of combined drugs with the single atorvastatin for CIAKI by inhibiting ERS specific molecular chaperone.
Method and Result: 50 Wistar rats were randomly divided into 5 groups: Group A (atorvastatin group, n=10); Group P (probucol + atorvastatin group, n=10); Group Q (alprostadil + atorvastatin group, n=10); Group NC (contrast group, n=10); Group N (control group, n=10). After treated with meglumine diatrizoate and different drugs, the kidneys were obtained for HE, TUNEL staining and real-time RT-PCR, western blot, immunohistochemitry to detect the expression of nucleic acid and protein levels of GRP78, GADD153/CHOP, Caspase-12 in the ERS pathways. Group NC has the significantly highest creatinine rise rate, expression level of protein and nucleic acid in the five groups, with the most serious cell injury and apoptosis in HE and TUNEL staining. Compared with the single atorvastatin group, creatinine rise rate and expression of protein in the combined medication groups were decreased to some extent, whose histological morphology was also improved. This was especially evident in the group Q.
Conclusion: The renal cell apoptosis induced by ERS pathway may play an important role in pathogenesis of CIAKI induced by meglumine diatrizoate. Atorvastatin, probucol and alprostadil can prevent the occurrence of CIAKI, may through the inhibition of cell apoptosis induced by ERS pathway. The protective effect for CIAKI of probucol or alprostadil combined with atorvastatin may be stronger than the single atorvastatin through ERS pathway, with the more effect of the combination of alprostadil and atorvastatin.
PEMBINAAN UMKM DALAM ASPEK KOMUNIKASI PEMASARAN SEBAGAI WUJUD PEMBERDAYAAN PEREMPUAN DI SEKITAR KAWASAN WISATA PANTAI
Authors: Habib Muhammad Alhada Fuadilah , Sutopo Sutopo
Published: July 2024

Abstrak: Penelitian ini mengkaji pemberdayaan perempuan pelaku UMKM di kawasan wisata pantai Kabupaten Tulungagung melalui pembinaan komunikasi pemasaran. Pemberdayaan perempuan sangat penting dalam meningkatkan kesejahteraan masyarakat lokal dan ekonomi daerah. Perempuan memainkan peran vital dalam UMKM di sektor pariwisata, terutama dalam usaha mikro, kecil, dan menengah. Melalui pelatihan dan pendampingan, perempuan dapat meningkatkan keterampilan manajerial dan pemasaran, yang berdampak positif pada kesejahteraan ekonomi dan sosial. Temuan penelitian menunjukkan bahwa pelatihan komunikasi pemasaran meningkatkan kapasitas perempuan dalam mengelola bisnis, meningkatkan kepercayaan diri, dan memperluas pasar melalui teknologi digital. Namun, UMKM di kawasan ini menghadapi tantangan seperti keterbatasan modal, akses pasar, dan keterampilan teknis. Program pemberdayaan yang berkelanjutan dan dukungan dari pemerintah serta organisasi non-pemerintah sangat diperlukan untuk mengatasi hambatan ini. Penelitian ini menyarankan pendekatan holistik yang mencakup pelatihan, akses teknologi, dan kolaborasi antara berbagai pemangku kepentingan untuk menciptakan ekosistem yang mendukung pertumbuhan UMKM. Dengan demikian, pemberdayaan perempuan pelaku UMKM dapat berkontribusi lebih besar pada pembangunan ekonomi dan sosial di kawasan wisata pantai Kabupaten Tulungagung.
Kata Kunci: Pemberdayaan Perempuan; UMKM; Komunikasi Pemasaran; Wisata Pantai.
Abstract: This study examines the empowerment of women entrepreneurs in micro, small, and medium enterprises (MSMEs) in the coastal tourist areas of Tulungagung Regency through marketing communication training. Women's empowerment is crucial for enhancing local community welfare and regional economic development. Women play a vital role in MSMEs in the tourism sector, especially in micro, small, and medium enterprises. Through training and mentoring, women can improve their managerial and marketing skills, positively impacting economic and social welfare. The study's findings indicate that marketing communication training enhances women's capacity to manage businesses, boosts their confidence, and expands their markets through digital technology. However, MSMEs in this area face challenges such as limited capital, market access, and technical skills. Sustainable empowerment programs and support from the government and non-governmental organizations are essential to overcome these barriers. This study suggests a holistic approach that includes training, technology access, and collaboration among various stakeholders to create an ecosystem that supports MSME growth. Thus, empowering women entrepreneurs in MSMEs can significantly contribute to economic and social development in the coastal tourist areas of Tulungagung Regency.
Keywords: Women's Empowerment; MSMEs; Marketing Communication; Coastal Tourism.