bluuebunny/crossref_metadata_2025 huggingface dataset:
Mobility Aware Energy Efficient Congestion Control in Mobile Wireless Sensor Network
Authors: Ahmad Awais , Jabbar Sohail , Paul Anand , Rho Seungmin
Published: March 2014

In this paper, we introduce a mobility aware and energy efficient congestion control protocol “time sharing energy efficient congestion control (TSEEC) for mobile wireless sensor network.” TSEEC is based on hybrid scheme of time division multiple access protocol (TDMA) and statistical time division multiple access (STDMA) protocol that inform the sensor nodes when to wake up and to go to listening state so as to save energy. This management helps in minimizing congestion and improving network energy conservation through its load based allocation (LBA) and time allocation leister (TAL) techniques. LBA is typically based on STDMA that uses sensor node information for assignment of dynamic timeslots to the sensor, nodes, whereas TAL targets the mobility management of sensor nodes that further comprises three main strategies of cluster member node that is, joining cluster, leaving cluster, and absence of data/redundant data with extricated time allocation (ETA), shift back time allocation (SBTA), and eScaped Time Allocation (STA) subtechniques. In addition, TSEEC protocol introduces the mobility pattern to control the mobile sensor node (MSN) movement to enable the protocol to effectively adapt itself to change the traffic environments and mobility. Mathematical analysis and NS2 simulation show that TSEEC outperforms SMAC in terms of energy consumption and packet deliver ratio. Furthermore, a comparative analysis of TSEEC with various well-known related MAC protocols is also given.
Effect of Various Pretreatment for Extracting Intracellular Lipid fromNannochloropsis oculataunder Nitrogen Replete and Depleted Conditions
Authors: Surendhiran Duraiarasan , Vijay Mani
Published: March 2014

Microalga is one of the most compelling microbial biomasses for biodiesel production. Various pretreatment processes, namely, enzyme treatment, lysis by acid, ultrasonicator, microwaves, autoclave, and 40% NaCl, for nitrogen replete and depleted algal cultures ofNannochloropsis oculatahad been carried out to check the most feasible and effective technique to disrupt cells for procuring lipids, for which concentrations were determined. Fatty acid composition, essential functional groups, and cell disruption were analyzed by GC-MS, FT-IR Spectroscopy, and Nile Red fluorescent microscopy, respectively. The present investigation showed that lipid yield was higher in nitrogen depleted cells than that in normally nourished cells. GC-MS revealed the presence of major fatty acids—palmitic, oleic, stearic, arachidic, lauric, and linoleic acids. Highest efficiency was found when cells were pretreated using acid for 3 h. The lipid content was calculated as 33.18% and 54.26% for nitrogen rich cells and nitrogen starved cells, respectively. This work thus aided in identifying the most eligible pretreatment process to avail lipids from cells, to convert them to eco-friendly and nonpolluting biodiesel.
Unclassified Diffuse Ductal Cholangiocarcinoma; Report of a Case
Authors: Aydın Ünal , Özsan İsmail , Karabuğa Türker , Alpdoğan Özcan , Ortaç Ragıp , Yoldaş Ömer , Şahin Erkan
Published: March 2014

Cholangiocarcinoma (CCA) is the second most common malignant tumor of the liver. It is simply classified as intrahepatic and extrahepatic CCA (including perihilar and distal extra hepatic CCA) according to the anatomic localization. Various classification systems were described for staging cholangiocarcinoma. We represent an interesting case of cholangiocarcinoma which is in the shadow area of classification by involving intrahepatic, hilar, and distal extra hepatic bile ducts. To our knowledge, this is the first case in the literature with diffuse bile duct involvement.
2D Direction of Arrival Estimation for Cross Array in the Presence of Mutual Coupling
Authors: Hu Weiwei , Zhang Aijun , Wang Changming
Published: March 2014

This paper proposes a new method for cross array to estimate two-dimensional direction of arrival (2-D DOA) in the presence of mutual coupling. In this method, the array elements which are affected by the same mutual coupling are chosen onx-axis andz-axis, respectively. Then a new matrix is constructed with the proper entries of cross covariance matrix of the chosen elements outputs onx-axis andz-axis. Propagation method (PM) and rotational invariance techniques for uniform linear array (ULA) are utilized in the constructed matrix to obtain two parameters correlated with elevations and azimuths. While calculating and pairing the two parameters, only once eigendecomposing and several division operations are required with the relationship among the matrix, its eigenvalues, and corresponding eigenvectors. Simulations are presented to validate the performance of the proposed method.
Dynamics of Graft Function Measured by DNA-Technology in a Patient with Severe Aplastic Anemia and Repeated Stem Cell Transplantation
Authors: Karastaneva Anna , Urban Christian , Lackner Herwig , Schwinger Wolfgang
Published: March 2014

Although bone marrow transplantation (BMT) from an HLA identical sibling is considered as treatment of choice in pediatric patients with severe aplastic anemia (SAA), a significant number of them experience graft failure (GF) after BMT. We report a case of an 8-year-old male patient with SAA who presented with a complicated posttransplant course due to parvovirus B19 infection and GF. A subsequent attempt to support the graft by antithymocyte globulin (ATG) and a peripheral stem cell boost resulted in transitory autologous recovery of hematopoiesis followed by mixed chimerism, supported by donor lymphocyte infusions (DLIs) and finally graft rejection with relapse of SAA. Permanent complete chimerism was achieved by a second BMT. Dynamics of graft function, measured by a single nucleotide polymorphism (SNPs) analysis, are discussed.
New Results and Generalizations for Approximate Fixed Point Property and Their Applications
Authors: Du Wei-Shih , Khojasteh Farshid
Published: March 2014

We first introduce the concept of manageable functions and then prove some new existence theorems related to approximate fixed point property for manageable functions andα-admissible multivalued maps. As applications of our results, some new fixed point theorems which generalize and improve Du's fixed point theorem, Berinde-Berinde's fixed point theorem, Mizoguchi-Takahashi's fixed point theorem, and Nadler's fixed point theorem and some well-known results in the literature are given.
Diffusion Processes Satisfying a Conservation Law Constraint
Authors: Bakosi J. , Ristorcelli J. R.
Published: March 2014

We investigate coupled stochastic differential equations governingNnonnegative continuous random variables that satisfy a conservation principle. In various fields a conservation law requires a set of fluctuating variables to be nonnegative and (if appropriately normalized) sum to one. As a result, any stochastic differential equation model to be realizable must not produce events outside of the allowed sample space. We develop a set of constraints on the drift and diffusion terms of such stochastic models to ensure that both the nonnegativity and the unit-sum conservation law constraints are satisfied as the variables evolve in time. We investigate the consequences of the developed constraints on the Fokker-Planck equation, the associated system of stochastic differential equations, and the evolution equations of the first four moments of the probability density function. We show that random variables, satisfying a conservation law constraint, represented by stochastic diffusion processes, must have diffusion terms that are coupled and nonlinear. The set of constraints developed enables the development of statistical representations of fluctuating variables satisfying a conservation law. We exemplify the results with the bivariate beta process and the multivariate Wright-Fisher, Dirichlet, and Lochner’s generalized Dirichlet processes.
Gender Differences in Pulmonary Function, Respiratory Symptoms, and Macrophage Proteomics among HIV-Infected Smokers
Authors: Rahmanian Shiva D. , Wood Karen L. , Lin Shili , King Mark A. , Horne April , Yang Shangbin , Wu Haifeng M. , Diaz Philip T.
Published: March 2014

Background. HIV-infected subjects have an increased incidence of pulmonary emphysema. There are known gender differences in COPD phenotypic expression and diagnosis, but this is not well characterized in lung disease related to HIV. We analyzed a group at risk for the development of COPD (HIV-infected smokers) to determine gender differences in pulmonary symptoms, pulmonary function tests, and HRCT appearances.Methods. This was a cross-sectional, baseline analysis of a prospective study performed between 2006 and 2010. We performed symptomatic, pulmonary function, and computed tomography assessments in 243 HIV-infected smokers. In a subset bronchoalveolar lavage was performed with proteomic analysis of their alveolar macrophages.Results. The majority of the participants were male 213 (87.6%). There was significantly higher percentage of cough and phlegm production in males. There was also a lower FEV1 and a higher RV in males than females. Proteomic analysis revealed 29 proteins with at least a 2-fold higher expression in males and 13 identified proteins that were higher in females.Conclusions. In this group of HIV-infected smokers, airway symptoms and pulmonary function test abnormalities were higher in men than women. These gender differences may be due to differential expression of certain proteins in this group.
Hypoxia-Induced Endothelial Damage and Microthrombosis in Myocardial Vessels of Newborn Landrace/Large White Piglets
Authors: Faa Armando , Xanthos Theodoros , Fanos Vassilios , Fanni Daniela , Gerosa Clara , Pampaloni Pietro , Pais Maria Elena , Faa Gavino , Iacovidou Nicoletta
Published: March 2014

Objective.Evaluating the presence of endothelial changes in myocardial vessels in an experimental model of hypoxia and resuscitation in newborn piglets.Methods.Fifty male Landrace/Large White neonatal piglets were studied: ten of them were allocated in group A (control group, SHAM-operated). In group B (forty animals, experimental group) normocapnic hypoxia was induced by decreasing inspired concentration of O2to 6%–8%. When the animals developed bradycardia or severe hypotension, reoxygenation was initiated. The animals of group B were allocated in 4 subgroups of 10, according to the concentration of O2they were resuscitated with (groups 1, 2, 3, and 4 received 18%, 21%, 40%, and 100% O2, resp.).Results.Control group animals did not show any significant endothelial lesions. Contrarily, endothelial lesions were detected in all experimental group cases. When these lesions were analyzed in the different heart zones, no significant difference in their incidence was observed; analyzing the frequency in the animals of the 4 subgroups, only microthrombosis showed a higher frequency in animals in groups 4 and 3.Conclusions.Endothelial damage represents a diffuse pathological feature in the myocardial vessels of piglets subjected to normocapnic hypoxia and resuscitation suggesting a possible role of hyperoxygenation in aggravating endothelial damage.
Flow Merging and Hub Route Optimization in Collaborative Transportation
Authors: Weng Kerui , Xu Zi-hao
Published: March 2014

This paper studies the optimal hub routing problem of merged tasks in collaborative transportation. This problem allows all carriers’ transportation tasks to reach the destinations optionally passing through 0, 1, or 2 hubs within limited distance, while a cost discount on arcs in the hub route could be acquired after paying fixed charges. The problem arises in the application of logistics, postal services, airline transportation, and so forth. We formulate the problem as a mixed-integer programming model, and provide two heuristic approaches, respectively, based on Lagrangian relaxation and Benders decomposition. Computational experiments show that the algorithms work well.
Performance Optimization, Prediction, and Adequacy by Response Surfaces Methodology with Allusion to DRF Technique
Authors: Shukla Lokesh , Nishkam Anita
Published: March 2014

The RSM introduces statistically designed experiments for the purpose of making inferences from data. The second-order model is the most frequently used approximating polynomial model in RSM. The most common designs for the second-order model are the 3kfactorial, Doehlert, Box-Behnken, and CCD. In this Box and Behnken design of three variables is selected as a representative of RSM and 70 : 30 polyester-wool DRF yarn knitted fabrics samples as a process representative. The survey reveals that second-order model is the most frequently used approximating polynomial model in RSM. The Box-Behnken is the most suited design for optimization and prediction of data in textile manufacturing and this model is well-suited for DRF technique yarn knitted fabric. The trend was as higher wool fiber length shows higher fabric weight, abrasion, and bursting strength, correlation of TM was not visible; however, role of strands spacing is found dominant in comparison to other variables; at 14 mm spacing it shows optimum behaviors. The optimum values were weight (gms/mt2) 206 at length 75 mm, TM 2.5 and 14 mm spacing, abrasion (cycles) 1325 at length 70 mm, TM 2.25 and 14 mm spacing, bursting (kg/cm2) 14.35 at length 70 mm, and TM 2.00 and 18 mm spacing. A selected variables, fiber length, TM, and strand spacing, have substantial influence. The adequacies of response surface equations are very high. The line trends of knitted fabric basic characteristics were almost the same for actual and predicted models. The difference (%) was in range of 1.21 to −1.45, 2.01 to −7.26, and 17.84 to −6.61, the accuracy (%) was in range of 101.45 to 98.79, 107.27 to 97.99, and 106.61 to 82.16, and the Discrepancy Factor (R-Factor) was noted to be 0.016, 0.002, and 0.229 for weight, abrasion, and bursting, respectively, between actual and predicted data. TheL-estimation factors for actual and predicted data were that (i) the ratio were in range of 1.01 to 0.99, 1.02 to 0.93, and 1.22 to 0.94 for weight, abrasion, and bursting, respectively, (ii) the multiple-ratio was in range of 1.26 to 0.86, (iii) the ratio product was in range of 1.22 to 0.92, and (iv) the toting ratio was in range of 1.02 to 0.94.
Synthesis and Biological Activities of 4-Aminoantipyrine Derivatives Derived from Betti-Type Reaction
Authors: Mohanram Ipsita , Meshram Jyotsna
Published: March 2014

The present work deals with the synthesis and evaluation of biological activities of 4-aminoantipyrine derivatives derived from a three-component Betti reaction. The synthesis was initiated by the condensation of aromatic aldehyde, 4-aminoantipyrine, and 8-hydroxyquinoline in presence of fluorite as catalyst in a simple one-step protocol. The reactions were stirred at room temperature for 10–15 min achieving 92–95% yield. The structures of synthesized derivatives were established on the basis of spectroscopic and elemental analysis. All derivatives 4(a–h) were screened in vivo and in vitro for anti-inflammatory and anthelmintic activity against a reference drug, Diclofenac and Albendazole, respectively. The screening results show that compounds 4c, 4d, 4f, and 4h were found to possess potential anti-inflammatory activity while compounds 4a, 4b, 4e, and 4g are potent anthelmintic agents when compared with reference drugs, respectively. The bioactivity of these derivatives has also been evaluated with respect to Lipinski’s rule of five using molinspiration cheminformatics software.
Manilkara zapota (Linn.) Seeds: A Potential Source of Natural Gum
Authors: Singh Sudarshan , Bothara Sunil B.
Published: March 2014

Mucilage isolated from seeds of Manilkara zapota (Linn.) P. Royen syn. is a plant growing naturally in the forests of India. This mucilage is yet to be commercially exploited, and characterized as polymer. Various physicochemical methods like particle size analysis, scanning electron microscopy, thermal analysis, gel permeation chromatography, X-ray diffraction spectrometry, zeta potential, Fourier transform infrared spectroscopy, and nuclear magnetic resonance spectroscopy have been employed to characterize this gum in the present study. Particle size analyses suggest that mucilage has particle size in nanometer. Scanning electron microscopy analysis suggests that the mucilage has irregular particle size. The glass transition temperature of the gum was observed to be 138°C and 136°C by differential scanning calorimetry and differential thermal analysis, respectively. The thermogravimetric analysis suggested that mucilage had good thermal stability. The average molecular weight of mucilage was determined to be 379180, by gel permeation chromatography, while the viscosity of mucilage was observed to be 219.1 cP. The X-ray diffraction spectrometry pattern of the mucilage indicates a completely amorphous structure. Elemental analysis of the gum revealed the contents of carbon, hydrogen, nitrogen, and sulfur to be 80.9 (%), 10.1 (%), 1.58 (%), and 512 (mg/kg), respectively. Mucilage had specific content of calcium, magnesium, potassium, lower concentrations of aluminum, cadmium, cobalt, lead, and nickel. The major functional groups identified from FT-IR spectrum include 3441 cm−1 (–OH), 1660 cm−1 (Alkenyl C–H & C=C Stretch), 1632 cm−1 (–COO–), 1414 cm−1 (–COO–), and 1219 cm−1 (–CH3CO). Analysis of mucilage by paper chromatography and 1D NMR, indicated the presence of rhamnose, xylose, arabinose, mannose, and fructose.
Metabotropic Glutamate Receptor 5 Negative Modulation in Phase I Clinical Trial: Potential Impact of Circadian Rhythm on the Neuropsychiatric Adverse Reactions—Do Hallucinations Matter?
Authors: Abou Farha Khalid , Bruggeman Richard , Baljé-Volkers Corine
Published: March 2014

Metabotropic Glutamate Receptor 5 (mGluR5) negative allosteric modulators (NAMs) may play a role in some psychiatric disorders such as anxiety and depression. The pharmacokinetic profile and pharmacodynamics effects of mGluR5-NAMs have been previously reported. We performed a post hoc analysis of pharmacological and clinical data obtained from 18 young healthy female subjects who received a mGluR5-NAM in the context of a phase I drug-drug interaction study between a mGluR5 NAM and a monophasic oral contraceptive. mGluR5-NAM was administered in an escalating bidaily dose level design. There was no interaction between the OC and mGluR5-NAM. Higher morning mGluR5-NAM plasma concentrations were found compared to evening concentrations. Most of the observed clinically significant neuropsychiatric adverse reactions occurred nocturnally and included visual (pseudo) hallucinations, insomnia accompanied by secondary behavioural disorders, and cognitive dysfunction symptoms of sufficient severity to interfere with daily functioning.
Circadian rhythm-related physiological variations in drug absorption and disposition may explain this pharmacokinetics-pharmacodynamics apparently disproportionate relationship. We suggest that clinical trials evaluating basic pharmacokinetic properties of psychiatric medications consider potential drug's chronopharmacokinetics. This may assist with dose optimization and minimize serious neuropsychiatric adverse reactions in the vulnerable psychiatric patient.
Efficacy of Three Light Technologies for Reducing Microbial Populations in Liquid Suspensions
Authors: Birmpa Angeliki , Vantarakis Apostolos , Paparrodopoulos Spyros , Whyte Paul , Lyng James
Published: March 2014

The aim of the current study was to evaluate the effectiveness of three nonthermal light technologies (NUV-Vis, continuous UV, and HILP) on their ability to inactivateEscherichia coliK12 andListeria innocua.  E. coliK12 was selected as a representative microorganism for the enterohaemorrhagic foodborne pathogenE. coliO157:H7 andL. innocuaas a surrogate microorganism for the common foodborne pathogenListeria monocytogenes, respectively. The liquid matrix used for the disinfection experiments was a liquid matrix (MRD solution). The results of the present study show that the HILP treatment inactivated bothE. coliandL. innocuamore rapidly and effectively than either continuous UV-C or NUV-vis treatment. With HILP at 2.5 cm from the lamp,E. coliandL. innocuapopulations were reduced by 3.07 and 3.77 log10CFU/mL, respectively, after a 5 sec treatment time, and were shown to be below the limit of detection (<0.22 log10CFU/mL) following 30 sec exposure to HILP (106.2 J/cm2). These studies demonstrate the bactericidal efficacy of alternative nonthermal light technologies and their potential as decontamination strategies in the food industry.
Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis
Authors: Popławska-Kita Anna , Telejko Beata , Siewko Katarzyna , Kościuszko-Zdrodowska Maria , Wawrusewicz-Kurylonek Natalia , Krętowski Adam , Hryniewicka Justyna , Dzięcioł Janusz , Bauer Witold , Milewski Robert , Szelachowska Małgorzata , Górska Maria
Published: March 2014

Aim. The aim of the study was to compare the expression of sodium iodide symporter (NIS), thyroglobulin (Tg), tumor necrosis factor-α(TNFα), and interleukin-1βgenes in patients with Hashimoto’s thyroiditis (HT) and healthy individuals.Subjects and Methods.Thyroid cells were obtained from 39 patients with HT and 15 controls by an ultrasound guided fine needle aspiration biopsy.Results. The patients with HT had lower Tg and NIS mRNA (P=0.002andP=0.001, resp.), as well as higher TNFαmRNA expression (P=0.049) than the controls. In the HT group Tg mRNA expression correlated positively with NIS mRNA expression (R=0.739,P=0.0001) and thyroid volume (R=0.465,P=0.0005), as well as negatively with TNFαmRNA expression (R=-0.490,P=0.001) and anti-peroxidase antibodies (TPOAb) level (R=-0.482,P=0.0002), whereas NIS mRNA expression correlated positively with thyroid volume (R=0.319,P=0.02), as well as negatively with TNFαmRNA expression (R=-0.529,P=0.0006) and TPOAb level (R=-0.422,P=0.001).Conclusions.Our results suggest that decreased Tg and NIS expression in thyroid cells may result in reduced active iodide transport and reduced thyroid volume in patients with HT.
Black Coloured Urine following Organophosphorus Poisoning: Report of Two Cases
Authors: Basheer Aneesh , Mookkappan Sudhagar , Shanmugham Vijay , Natarajan Nagarajan , Kulirankal Kiran
Published: March 2014

Organophosphorus poisoning is common in rural Asia. Clinical features result from overactivity of acetylcholine receptors. Blackish discoloration of urine is not a feature of organophosphorus poisoning. Only one case of black colored urine following quinalphos poisoning has been reported in literature. We report two cases of organophosphorus poisoning from two different compounds, following which patients passed black colored urine, in the absence of haemolysis or rhabdomyolysis. These cases indicate that blackish discoloration of urine in organophosphorus poisoning might not be as uncommon as it was believed to be. Besides, urinary excretion of metabolites might be an underlying mechanism, rather than hemolysis.
Unusual Seven Coordination of Oxovanadium(V) Oximato Complex: Synthesis and X-Ray Crystal Structure
Authors: Elsayed Shadia A. , El-Hendawy Ahmed M. , El-Mahdy Mohamed I.
Published: March 2014

The new oxovanadium(V) complex, [VO(acac)(dametsc)] (1) (acac = acetylacetonate (-1), H2dametsc = diacetylmonoxime-4-ethylthiosemicarbazone), has been prepared and characterized by studying its physicochemical properties. The X-ray crystal structure of the complex (1) has been determined and showed the presence of vanadium(V) atom in a unique heptacoordination state with distorted pentagonal bipyramidal geometry. The oximato ligand in the pentagonal plane is bonded to the central vanadium atom in dihapto (η2= N,O) manner with the formation of three membered ring, while the other three coordination sites in the plane are occupied by hydrazinic imine nitrogen, thiolate sulfur, and one of the acac oxygen atoms. The axial position sites are defined by the other acac oxygen and the trans oxo-atom. The supramolecular structure of the complex is exclusively constructed by intermolecular interactions, N–H⋯O and C–H⋯O.
Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
Authors: Neofytou Kyriakos , Wasan Harpreet , Mudan Satvinder
Published: March 2014

Surgical resection is the only potentially curative strategy in the treatment of patients with colorectal liver metastases (CLM). Unfortunately, only about 10%–15% of patients are candidates for resection. Preoperative chemotherapy aims to increase the number of patients that may be eligible for liver resection by downsizing liver metastases. For patients with unresectable, chemotherapy refractory CLM the available treatment options are limited. Selective interarterial radiation therapy (SIRT) is one of the most promising treatment options for this group of patients. Although only a small number of these patients have been reported as becoming candidates for potentially curative hepatic resection following sufficient reduction in the volume of liver metastases, the question arises regarding the safety of liver resection in these patients. We report a case of a patient who presented unresectable liver relapse of CLM after previous right hepatectomy. He underwent SIRT which resulted in downsizing of the liver metastases making the patient candidate for left lateral sectionectomy. He underwent the redo hepatectomy without any complications. To the best of our knowledge, this is the first reported case of redo hepatectomy after SIRT for CLM.
Novel Technologies for Design and Analysis of Switching Mode Power-Supply Circuit Based on Solitary Electromagnetic Wave Theory
Authors: Tohya Hirokazu , Toya Noritaka
Published: March 2014

The novel solitary electromagnetic wave (SEMW) theory and the novel design methodologies of the switching mode power supply circuit (SMPC) are presented. The SEMW theory was developed as a basic theory of the design of all kinds of the switching mode circuit including SMPC by fusing the physics of semiconductor, nonlinear undulation, and electromagnetic wave. When the SEMW theory is used, the electromagnetic analysis of SMPC becomes possible by using only the real parameters based on the physics. The technologies of the low impedance lossy line (LILL) which is used to the DC line and the matched impedance lossy line (MILL) which is used to the switching line are also presented. They are effective for suppressing the electromagnetic interference. SMPC can be reconfigured to the quasistationary state closed circuit (QSCC) by applying LILL and MILL in accordance with the SEMW theory. No electromagnetic interference exist in QSCC. The buck converter which is one of the most popular DC-DC converters is presented as an example of the method for being reconfigured to QSCC. The conventional design tools which includes SPICE based on the AC circuit theory will be effective for the design and analysis of the inside circuit of QSCC.
Therapeutic Potential of Hydrazones as Anti-Inflammatory Agents
Authors: Kajal Anu , Bala Suman , Sharma Neha , Kamboj Sunil , Saini Vipin
Published: March 2014

Hydrazones are a special class of organic compounds in the Schiff base family. Hydrazones constitute a versatile compound of organic class having basic structure (R1R2C=NNR3R4). The active centers of hydrazone, that is, carbon and nitrogen, are mainly responsible for the physical and chemical properties of the hydrazones and, due to the reactivity toward electrophiles and nucleophiles, hydrazones are used for the synthesis of organic compound such as heterocyclic compounds with a variety of biological activities. Hydrazones and their derivatives are known to exhibit a wide range of interesting biological activities like antioxidant, anti-inflammatory, anticonvulsant, analgesic, antimicrobial, anticancer, antiprotozoal, antioxidant, antiparasitic, antiplatelet, cardioprotective, anthelmintic, antidiabetic, antitubercular, trypanocidal, anti-HIV, and so forth. The present review summarizes the efficiency of hydrazones as potent anti-inflammatory agents.
Modeling and Dynamical Behavior of Rotating Composite Shafts with SMA Wires
Authors: Ren Yongsheng , Dai Qiyi , An Ruijun , Zhu Youfeng
Published: March 2014

A dynamical model is developed for the rotating composite shaft with shape-memory alloy (SMA) wires embedded in. The rotating shaft is represented as a thin-walled composite of circular cross-section with SMA wires embedded parallel to shaft’s longitudinal axis. A thermomechanical constitutive equation of SMA proposed by Brinson is employed and the recovery stress of the constrained SMA wires is derived. The equations of motion are derived based on the variational-asymptotical method (VAM) and Hamilton’s principle. The partial differential equations of motion are reduced to the ordinary differential equations of motion by using the Galerkin method. The model incorporates the transverse shear, rotary inertia, and anisotropy of composite material. Numerical results of natural frequencies and critical speeds are obtained. It is shown that the natural frequencies of the nonrotating shaft and the critical rotating speed increase as SMA wire fraction and initial strain increase and the increase in natural frequencies becomes more significant as SMA wire fraction increases. The initial strain of SMA wires appears to have marginal effect on dynamical behaviors of the shaft. The actuation performance of SMA wires is found to be closely related to the ply-angle.
Characterization of Multiwalled Carbon Nanotube-Reinforced Hydroxyapatite Composites Consolidated by Spark Plasma Sintering
Authors: Kim Duk-Yeon , Han Young-Hwan , Lee Jun Hee , Kang Inn-Kyu , Jang Byung-Koog , Kim Sukyoung
Published: March 2014

Pure HA and 1, 3, 5, and 10 vol% multiwalled carbon nanotube- (MWNT-) reinforced hydroxyapatite (HA) were consolidated using a spark plasma sintering (SPS) technique. The relative density of pure HA increased with increasing sintering temperature, but that of the MWNT/HA composite reached almost full density at 900°C, and then decreased with further increases in sintering temperature. The relative density of the MWNT/HA composites increased with increasing MWNT content due to the excellent thermal conductivity of MWNTs. The grain size of MWNT/HA composites decreased with increasing MWNT content and increased with increasing sintering temperature. Pull-out toughening of the MWNTs of the MWNT/HA composites was observed in the fractured surface, which can be used to predict the improvement of the mechanical properties. On the other hand, the existence of undispersed or agglomerate MWNTs in the MWNT/HA composites accompanied large pores. The formation of large pores increased with increasing sintering temperature and MWNT content. The addition of MWNT in HA increased the hardness and fracture toughness by approximately 3~4 times, despite the presence of large pores produced by un-dispersed MWNTs. This provides strong evidence as to why the MWNTs are good candidates as reinforcements for strengthening the ceramic matrix. The MWNT/HA composites did not decompose during SPS sintering. The MWNT-reinforced HA composites were non-toxic and showed a good cell affinity and morphologyin vitrofor 1 day.
The Effect of Water Stress on Some Morphological, Physiological, and Biochemical Characteristics and Bud Success on Apple and Quince Rootstocks
Authors: Bolat Ibrahim , Dikilitas Murat , Ercisli Sezai , Ikinci Ali , Tonkaz Tahsin
Published: March 2014

The effects of different water stress (control, medium, and severe) on some morphological, physiological, and biochemical characteristics and bud success of M9 apple and MA quince rootstocks were determined. The results showed that water stress significantly affected most morphological, physiological, and biochemical characteristics as well as budding success on the both rootstocks. The increasing water stress decreased the relative shoot length, diameter, and plant total fresh and dry weights. Leaf relative water content and chlorophyll index decreased while electrolyte leakage increased with the increase of water stress in both rootstocks. An increase in water stress also resulted in reduction in budding success in Vista Bella/M9 (79.33% and 46.67%) and Santa Maria/MA (70.33% and 15.33%) combinations. However, the water stress in Santa Maria/MA was more prominent. The increase in water stress resulted in higher peroxidase activities as well as phenol contents in both rootstocks. Although catalase activity, anthocyanin, and proline contents increased with the impact of stress, this was not statistically significant. The results suggest that the impact of stress increased with the increase of water stress; therefore, growers should be careful when using M9 and MA rootstocks in both nursery and orchards where water scarcity is present.
Characterization of Corrosive Bacterial Consortia Isolated from Water in a Cooling Tower
Authors: Aruliah Rajasekar , Ting Yen-Peng
Published: March 2014

An analysis of a culturable corrosive bacterial community in water samples from a cooling tower was performed using traditional cultivation techniques and its identification based on 16S rRNA gene sequence. Seven aerobic bacterial species were identified: Pseudomonas putida ARTYP1, Pseudomonas aeruginosa ARTYP2, Massilia timonae ARTYP3, Massilia albidiflava ARTYP4, Pseudomonas mosselii ARTYP5, Massilia sp. ARTYP6, and Pseudomonas sp. ARTYP7. Although some of these species have commonly been observed and reported in biocorrosion studies, the genus Massilia is identified for the first time in water from a cooling tower. The biocorrosion behaviour of copper metal by the new species Massilia timonae ARTYP3 was selected for further investigation using a weight loss method, as well as electrochemical and surface analysis techniques (SEM, AFM, and FTIR). In contrast with an uninoculated system, thin bacterial biofilms and pitting corrosion were observed on the copper metal surface in the presence of M. timonae. The use of a biocide, bronopol, inhibited the formation of biofilm and pitting corrosion on the copper metal surface.
Nonuniform Dependence on Initial Data of a Periodic Camassa-Holm System
Authors: Wang Xiaohuan
Published: March 2014

This paper is concerned with some properties of a periodic two-component Camassa-Holm system. By constructing two sequences of solutions of the two-component Camassa-Holm system, we prove that the solution map of the Cauchy problem of the two-component Camassa-Holm system is not uniformly continuous inHs(𝕊),s>5/2.
Interstitial Keratitis, Vertigo, and Vasculitis: Typical Cogan’s Syndrome
Authors: Azami Ahad , Maleki Nasrollah , Kalantar Hormozi Mohammadreza , Tavosi Zahra
Published: March 2014

Cogan’s syndrome (CS) is a chronic inflammatory disorder of unknown etiology that most commonly affects young adults. Clinical hallmarks are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between CS and systemic vasculitis as well as aortitis also exists. The diagnosis of CS is based upon presence of characteristic inflammatory eye disease and vestibuloauditory dysfunction. We describe classic Cogan’s syndrome in a 47-year-old female from Ardabil. The patient was admitted with headache, vertigo, nausea, vomiting, right leg claudication, musculoskeletal pains, bilateral hearing loss, and blindness for the past two months. Ophthalmologic examination revealed that visual acuity was 0.1 bilaterally. Conjunctival hyperemia, bilateral cataract, and interstitial keratitis were detected with a slit lamp examination. Pure tone audiogram (PTA) and auditory brain stem response (ABR) showed bilateral sensorineural hearing loss. The other differential diagnosis of CS was studied and ruled out. Pulse i.v. methylprednisolone and cyclophosphamide were given and were followed by oral prednisolone and cyclophosphamide. Clinical follow-up showed partial improvement.
Evidence for the Existence of Triple-Negative Variants in the MCF-7 Breast Cancer Cell Population
Authors: Leung Euphemia , Kim Ji Eun , Askarian-Amiri Marjan , Finlay Graeme J. , Baguley Bruce C.
Published: March 2014

The MCF-7 line, derived in 1973 from a malignant pleural effusion, is one of the most commonly used culture models for human breast cancer. Despite its long history, MCF-7 is a surprisingly heterogeneous line. We previously showed that if MCF-7 cells were cultured for a prolonged period either in the absence of estrogen or in the presence of the antiestrogen tamoxifen, sub-lines were selected that differed from the parental line in ploidy, mean cell volume, signaling pathway usage, and drug sensitivity. This suggests a process of selection of preexisting variants rather than of adaptation of the parental line. All the sublines were estrogen receptor (ER) positive, raising the question of whether MCF-7 also contains ER negative variants. Here, we have looked for such variants by culturing for a prolonged period in the presence of fulvestrant, an estrogen antagonist that has no estrogen agonist activity. Three sublines were developed, each of which was ER negative, progesterone receptor (PR) negative and expressed only a low level of HER2. Each of the variants differed from the original MCF-7 line in ploidy, modal cell volume, and signaling pathway usage. Control experiments in which cells were cultured for a prolonged period in the absence of estrogen selected for variants that were ER and PR positive. The properties of the triple-negative MCF-7 were compared with those of an existing triple-negative cell line, MDA-MB-231, and human epidermal growth factor receptor 2 (HER2)+ SKBr3, as well as from those of the “immortalized” breast epithelial line MCF10A. The results suggest that new variants or phenotypes of MCF-7 might be generated continuously in culture, and by implication this might apply to breast cancer development and even normal breast epithelial developmentin vivo.
The PVC Stripping Process Predictive Control Based on the Implicit Algorithm
Authors: Gao Shuzhi , Luan Liangliang
Published: March 2014

According to the nonlinear and parameters time‐varying characteristics of stripper temperature control system, the PVC stripping process Generalized Predictive Control based on implicit algorithm is proposed. Firstly, supporting vector machine is adopted to dynamically modelize for the stripper temperature; Secondly, combining with real‐time model linearized of nonlinear model, a predictive model is linearized for real‐time online correction. Then, the implicit algorithm is used for optimal control law. Finally, the simulation results show that the algorithm has excellent validity and robustness of temperature control of the stripper.
Localized Giant Cell Tenosynovial Tumor Seen in the Knee Joint
Authors: Beytemür Ozan , Albay Cem , Tetikkurt Ümit Seza , Öncü Mehmet , Baran Mehmet Ali , Çağlar Sever , Güleç Mehmet Akif
Published: March 2014

Tenosynovial giant cell tumor is a locally aggressive tumor arising from the synovia of the fibrous tissue surrounding the joints, tendon sheaths, mucosal bursas, and tendons. Although it is often to be observed at the hand, localized form is very rare in the knee joint. In this case report, we aimed to present a very rare case of a surgically treated intra-articular giant cell tenosynovial tumor arising from the hoffa’s infrapatellar fat pad of a 19-year-old male patient, by reviewing the literature. The patient we have treated with marginal excision was asymptomatic at the 14th month in the controls and recurrence was not detected.
Stress-Strain Relationship of Ca(OH)2-Activated Hwangtoh Concrete
Authors: Yang Keun-Hyeok , Mun Ju-Hyun , Hwang Hey-Zoo
Published: March 2014

This study examined the stress-strain behavior of 10 calcium hydroxide (Ca(OH)2)-activated Hwangtoh concrete mixes. The volumetric ratio of the coarse aggregate (Vagg) and the water-to-binder (W/B) ratio were selected as the main test variables. TwoW/Bratios (25% and 40%) were used and the value ofVaggvaried between 0% and 40.0%, and 0% and 46.5% forW/Bratios of 25% and 40%, respectively. The test results demonstrated that the slope of the ascending branch of the stress-strain curve of Ca(OH)2-activated Hwangtoh concrete was smaller, and it displayed a steeper drop in stress in the descending branch, compared with those of ordinary Portland cement (OPC) concrete with the same compressive strength. This trend was more pronounced with the increase in theW/Bratio and decrease inVagg. Based on the experimental observations, a simple and rational stress-strain model was established mathematically. Furthermore, the modulus of elasticity and strain at peak stress of the Ca(OH)2-activated Hwangtoh concrete were formulated as a function of its compressive strength andVagg. The proposed stress-strain model predicted the actual behavior accurately, whereas the previous models formulated using OPC concrete data were limited in their applicability to Ca(OH)2-activated Hwangtoh concrete.
Complete Renal Artery Embolization in a Comorbid Patient with an Arteriovenous Malformation
Authors: Thayaparan Anthony , Amer Tarik , Mahdi Eamon , Aboumarzouk Omar , Hughes Owen
Published: March 2014

Renal arteriovenous malformations are uncommon and are rarely a cause for presentation. However, they can occasionally pose life-threatening problems. We present a case of an elderly female who underwent a complete left renal artery embolization, following a difficult presentation complicated by advanced dementia and multiple comorbidities. This is the first documented case of complete renal artery embolisation used to treat a renal AVM.
Pinning Group Synchronization in Complex Dynamical Networks with Different Groups of Oscillators
Authors: Deng Guangming
Published: March 2014

This paper investigates the pinning control schemes and corresponding criteria for group synchronization in a complex dynamical network with different types of chaotic oscillators. We present the linear pinning and adaptive pinning control schemes to make different groups of oscillators synchronize to their own synchronization states, respectively. The globally asymptotically stable criteria for group synchronization are derived, which indicate that the group synchronization can be realized only by pinning a part of nodes in a general network. Finally, some numerical simulations are provided to verify the theoretical results.
A Delayed and Rather Unusual Presentation of a Bladder Injury after Pelvic Trauma: 5 Years after a Road Traffic Accident
Authors: Davarinos Nikolaos , Thornhill John , McElwain JP , Moore David
Published: March 2014

Associated injuries frequently occur in patients who sustain fractures of the pelvis. Specifically, high-energy trauma resulting in pelvic fractures places the bladder and urethra at risk for injury, often resulting in significant complications. Timely identification and management of genitourinary injuries minimize associated morbidity. Prompt injury identification depends upon a systematic evaluation with careful consideration of the mechanism of injury. Physical examination is pertinent as well as analysis of the urine and appropriate diagnostic imaging. Despite such increased vigilance genitourinary injuries get missed and delayed presentations in the order of a few weeks have been well documented. To our knowledge, this is the first report of its kind in the literature showing such a particularly delayed (5 years) and rather unusual presentation of a bladder injury after pelvic trauma.
Oral and Dental Considerations in Pediatric Leukemic Patient
Authors: Padmini Chiyadu , Bai K. Yellamma
Published: March 2014

Throughout the world, there have been drastic decline in mortality rate in pediatric leukemic population due to early diagnosis and improvements in oncology treatment. The pediatric dentist plays an important role in the prevention, stabilization, and treatment of oral and dental problems that can compromise the child’s health and quality of life during, and follow up of the cancer treatment. This manuscript discusses recommendations and promotes dental care of the pediatric leukemic patients.
Toona sinensisInhibits LPS-Induced Inflammation and Migration in Vascular Smooth Muscle Cells via Suppression of Reactive Oxygen Species and NF-κB Signaling Pathway
Authors: Yang Hsin-Ling , Huang Pei-Jane , Liu Yi-Ru , Kumar K. J. Senthil , Hsu Li-Sung , Lu Te-Ling , Chia Yi-Chen , Takajo Tokuko , Kazunori Anzai , Hseu You-Cheng
Published: March 2014

Toona sinensisis one of the most popular vegetarian cuisines in Taiwan and it has been shown to possess antioxidant, antiangiogenic, and anticancer properties. In this study, we investigated the antiatherosclerotic potential of aqueous leaf extracts fromToona sinensis(TS; 25–100 μg/mL) and its major bioactive compound, gallic acid (GA; 5 μg/mL), in LPS-treated rat aortic smooth muscle (A7r5) cells. We found that pretreatment with noncytotoxic concentrations of TS and GA significantly inhibited inflammatory NO andPGE2production by downregulating their precursors, iNOS and COX-2, respectively, in LPS-treated A7r5 cells. Furthermore, TS and GA inhibited LPS-induced intracellular ROS and their corresponding mediator, p47phox. Notably, TS and GA pretreatment significantly inhibited LPS-induced migration in transwell assays. Gelatin zymography and western blotting demonstrated that treatment with TS and GA suppressed the activity or expression of MMP-9, MMP-2, and t-PA. Additionally, TS and GA significantly inhibited LPS-induced VEGF, PDGF, and VCAM-1 expression. Further investigation revealed that the inhibition of iNOS/COX-2, MMPs, growth factors, and adhesion molecules was associated with the suppression of NF-κB activation and MAPK (ERK1/2, JNK1/2, and p38) phosphorylation. Thus,Toona sinensismay be useful for the prevention of atherosclerosis.
Robust Sampled‐Data H∞ Control for Vibration Mitigation of Offshore Platforms with Missing Measurements
Authors: Cai Mingjie , Xiang Zhengrong , Karimi Hamid Reza
Published: March 2014

This paper presents a robust sampled‐data H∞ control for vibration attenuation of offshore platforms with missing measurements subject to external wave force. It is well known that the phenomena of missing measurements are unavoidable due to various reasons, such as sensor aging and sensor temporal failure, which may degrade the control system performance or even cause instability. For active vibration control of offshore platforms with sampling measurements, to deal with the missing measurements, a robust sampled‐data H∞ control method is proposed in this paper. The robust sampled‐data H∞ state feedback controller is obtained in terms of the solvability of certain linear matrix inequalities (LMIs). Finally, simulations on an offshore platform are exploited to demonstrate the effectiveness of the proposed method. The simulation results show that the designed robust sampled‐data H∞ control scheme is effective to attenuate the external wave force in the presence of missing measurements.