bluuebunny/crossref_metadata_2025 huggingface dataset:
Skladištenje podataka u DNK molekulima
Authors: Josipović Andrea , Kovacevic Mladen
Published: July 2022

Potrebe za novim alternativama skladištenja sve veće količine podataka su evidentne. Čuvanje podataka u DNK molekulima se javlja kao jedna od opcija koja ima brojne prednosti u odnosu na postojeće mogućnosti. Kakav uticaj može imati na čitavu sferu skladištenja podataka, način realizacije i njene prednosti i mane detaljno su analizirane u ovom radu.
KONFIGURACIJA REVERZNOG PROKSIJA
Authors: Kostović Lara Mimica
Published: July 2022

U ovom radu predstavljena je tehnolo­gija reverznih proksi servera kao i konfiguracija istih. Naglasak je na njihovim osnovnim principima, mogućnos­tima primene, prednostima i nedostacima. U okviru rada posebno je istaknuta njihova arhitektura, kao i primena u preusmeravanju mrežnog prometa prema opterećenju. Kao primer konfiguracije i testiranja opisana je imple­mentacija sistema za praćenje vrednosti ulaganja u kriptovalute. Prilikom implementacije korišćene su sledeće tehnologije: Node.js, Nest.js i TypeScript. Za implementaciju reverznog proksi servera korišćen je NGINX.
КВАЛИТЕТ ЕЛЕКТРИЧНЕ ЕНЕРГИЈЕ У ПОСЛОВНИМ ЗГРАДАМА
Authors: Сатарић Стефан , Катић Владимир , Чорба Золтан
Published: July 2022

У овом раду је описано и анализи­рано мерење квалитета електричне енергије у три типичне пословне зграде у којима доминирају мали нелинеарни потрошачи, претежно кластери персо­налних рачунара. Процењене су девијације струја и напона услед виших хармоника и упоређене са важећим стандардима.
DER U MIKROMREŽI – SIMULACIJE U RAZNIM REŽIMIMA RADA
Authors: Radosavčev Dušan , Katić Vladimir , Stanisavljević Aleksandar
Published: July 2022

U ovom radu analiziran je uticaj distribuiranih elektroenergetskih resursa (DER) u mikro­mreži u različitim režimima rada. Simulacija je urađena u programskim paketima Matlab/Simulink i HOMER.
IMPLEMENTACIJA APLIKACIJE ZA SPORTSKA KLAĐENJA PRIMENOM ETHEREUM PLATFORME
Authors: Antolović Igor
Published: July 2022

U ovom radu predstavljeno je potencijalno rešenje za decentralizovanu aplikaciju za sportsku kladionicu u okviru Ethereum blockchain mreže. Objašnjenje su teorijske osnove i navedeni izazovi koji se susreću u ovom domenu. Opisane su terminologije vezane za ovu decentralizovanu aplikaciju kao što su blockchain tehnologija, Ethereum blockchain, koncept pametnih ugovora, Oracle entiteti i Solidity jezik. Na kraju je prikazan model i opis implementacije sistema, kao i završna zaključena zapažanja.
LINEARNI SISTEM ZA PRETVARANJE ENERGIJE MORSKIH TALASA U ELEKTRIČNU ENERGIJU
Authors: Aleksić Milena , Dumnić Boris
Published: July 2022

U ovom radu su predstavljeni osnovni tipovi uređaja za konverziju energije morskih talasa u električnu. Poseban akcenat je stavljen na engl. point absorber-e zasnovane na bovnom elementu sa linearnim generatorom, kao osnovnom delu električnog podsklopa. U radu je predstavljen matematički model linearnog sinhronog generatora sa stalnim magnetima, za potrebe simulacionog modela kreiranog u MATLAB softverskom okruženju. Nadalje je izvršena analiza odziva simulicionog modela, koji su u samom zaključku upoređeni sa drugim sistemima za konverziju morskih talasa u električnu energiju.
РАЗВОЈ АПЛИКАЦИЈЕ ЗА УПРАВЉАЊЕ РЕСТОРАНОМ РАДИ ПОМОЋИ СТУДЕНТИМА У УСВАЈАЊУ ЗНАЊА ИЗ ПРЕДМЕТА СПЕЦИФИКАЦИЈА И МОДЕЛОВАЊЕ СОФТВЕРА
Authors: Јовић Лазар
Published: July 2022

Држећи вежбе на предмету Спе­цификација и моделовање софтвера, на другој години смера Софтверско инжењерство и информационе технологије, увиђено је да постоји потреба за пројек­том који би студентима пружио увид у комплетно градиво примењено на реалан систем. Приказан је пут развоја софтвера, у који су укључени специфи­кација, моделовање, као и имплементација апликације која представља систем за управљање ресторана. Дијаграми који представљају UML моделе система креирани су у алату Magic Draw, док је имплемента­ција рађена у Java програмском језику, уз потребу Swing библиотеке за графички кориснички интерфејс.
UPRAVLJANJE VETROELEKTRANOM U USLOVIMA POREMEĆAJA U MREŽI
Authors: Perić Miljan , Katić Vladimir , Stanisavljević Aleksandar
Published: July 2022

U radu je razmatrana energiju vetra. Cilj ovog rada je analiza mogućnosti upravljanja vetroelektranom u uslovima poremećaja u mreži. Za analizu su korišćeni modeli iz Matlab/Simulink-a, kao i sopstveno razvijeni. Izvršene su izvršene su simulacije različitih vrsta poremećaja, koji se dešavaju u EES i analiziran je odziv sistema.
KLIJENTSKA APLIKACIJA ZA PRISTUP ETHEREUM PLATFORMI
Authors: Jurić Marko
Published: July 2022

U ovom radu opisani su osnovni principi distribuiranih sistema, razvoj blokčejn tehnologija kroz tri faze, pojam Ethereum platforme, kao i arhitektura klijenata za pristup Ethereum mreži. Predstavljeno je rešenje u vidu implementacije promene na Ethereum klijentu kao posledice zahteva Ethereum zajednice za ažuriranje Ethereum platforme
POZAJMLJIVANJE U KRIPTO VALUTAMA
Authors: Grujić Aleksandra
Published: July 2022

U ovom radu opisana je arhitektura sistema za pozajmljivanje u kripto valutama i način na koji funkcioniše pomoću pametnih ugovora. Pored toga opisani su centralizovani i decentralizovani sistemi i njihove prednosti i mane, kao i osnovni koncepti distribuiranih sistema i blokčejn tehnologije sa fokusom na Ethereum-u.
АНАЛИЗА АЛАТА ЗА КРЕИРАЊЕ ГРАФИЧКЕ КОНКРЕТНЕ СИНТАКСЕ НАМЕНСКИХ ЈЕЗИКА
Authors: Јовкић Јован
Published: July 2022

У овом раду описан је графички наменски језик за моделовање рецепата за припрему јела. Описано је окружење које је коришћено за израду апстракне синтаксе, а након тога приказана је апстрактна синтакса овог језика, као и детаљан опис сваког од концепата. Графичка конкретна синтакса је моделована уз помоћ три различита алата. Сваки алат је детаљно описан, односно описане су све технологије које су кориштене у изради мастер рада. Након тога приказана је примена сваког појединачног алата на изради конкретне синтаксе језика за приказивање рецепата. Овај део представља и круцијалну тачку самог рада. На крају су укратно сумирана искуства употребе сва три алата. За развој метамодела коришћено је окружење Eclipse Modeling Framework. За развој конкретне синтаксе коришћени су следећи алати: Sirius, Eugenia и VisualStudio.
АНАЛИЗА ПЕРФОРМАНСИ УПИТА У РЕЛАЦИОНИМ БАЗАМА ПОДАТАКА У ЗАВИСНОСТИ ОД УПОТРЕБЕ ИНДЕКСА
Authors: Арсенијевић Никола
Published: July 2022

Kреирана је једноставна релациона база података и мерено је време потребно да се изврше различити типови упита над базом података, користећи различите индексе. База података се састоји из 20 табела исте шеме релације али са променљивим бројем насумично генерисаних торки. Над сваком од њих су креирани индекси типа Б-стабло и бинарни индекс. Са свим релацијама и свим типовима индекса вршило се 7 одабраних, фреквентних упита и мерено је просечно време одзива. На крају су сва добијена мерења приказана графички у трослојној веб апликацији.
RAZVOJ RAČUNARSKE IGRE „HAPPY BIKER“
Authors: Mendrei Andrea
Published: July 2022

U ovom radu je opisan tok razvoja računarske igre namenjenoj deci. Opisan je celokupan tok igre, osnovna pravila i prepreke u igri. Zatim je opisan način modelovanja nekih modela u igri. Dalje, u radu se govori i o položajima kamera i zvučnim efektima imple­mentiranim u igri. Na kraju je ukratko opisan i pozadinski kod koji je korišćen u igri.
STRUJNI LIMITERI – IZBOR LOKACIJE ZA OGRANIČENJE VREDNOSTI STRUJE KRATKOG SPOJA
Authors: Šavija Jelena
Published: July 2022

U ovom radu su detaljno objašnjeni tipovi strujnih limitera, kao i kratki spojevi. Detaljnije su pojašnjeni određeni algoritmni za određivanje optimalne lokacije strujnih limitera. Dati su rezultati proračuna kratkog spoja određene distributivne mreže bez i sa strujnih limitera, kao i rezultati pretrage optimalne lokacije tih strujnih limitera.
NELINEARNA STATIČKA ANALIZA VIŠESPRATNE ZIDANE ZGRADE U NOVOM SADU
Authors: Kojić Božidar
Published: July 2022

Dokaz nosivosti za seizmička dejstva se sprovodi putem nelinearne statičke analize (“pushover”), koja se u Evrokodu daje kao alternativa linearnim metodama analize, ali i za verifikaciju performansi postojećih objekata. Pri analizi kapaciteta, razmatrana su granična stanja ograničenja oštećenja (DL), nosivosti (SD) i blizu kolapsa (NC). Prvu celinu rada čini tehnički opis konstrukcije sa osvrtom na način dimenzionisanja elemenata kosntrukcije. Drugu celinu čine teorijska poglavlja o odredbama Evrokodova 8-1 i 8-3, o načinima analize konstrukcija na seizmička dejstva i o načinima modeliranja zidanih konstrukcija. Praktični deo prikazuje nelinearnu statičku analizu i zaključke, na osnovu dobijenih rezultata, i opravdanost propisa za jednostavne zidane konstrukcije i propisanih vrednosti faktora ponašanja u Evrokodu 8.
PROJEKAT AB VIŠESPRATNE STAMBENE ZGRADE PREMA EVROKODU I UPOREDNA ANALIZA PRORAČUNA GRANIČNOG STANJA TRANSVERZALNIH SILA PREMA EC2 I BAB87
Authors: Erić Vladimir
Published: July 2022

Ovim radom predstavljena je analiza opterećenja i statičko-dinamički proračun armirano betonske konstrukcije sa dimenzionisanjem elemenata prema Evrokodu. Izvršeno je i upoređivanje proračuna transverzalnih sila prema BAB87 i Evrokodu.
PRINCIPI LEAN KONCEPTA U PROIZVODNIM PROCESIMA
Authors: Brujić Dejana
Published: July 2022

Lean proizvodnja predstavlja jedan kompletan sistem upravljanja preduzećem sa ciljem da se  eliminišu gubici. Primenom lean alata koji su sastavni deo Lean koncepta omogućuje se da preduzeće poveća produktivnost, obezbedi visok kvalitet proizvoda i snizi cene svojih proizvoda.
PROJEKAT ARMIRANOBETONSKE KONSTRUKCIJE VIŠESPRATNE ZGRADE KONSTRUKTIVNOG SISTEMA DUKTILNIH ZIDOVA
Authors: Lazić Stevo
Published: July 2022

Projektovana je armiranobetonska konstrukcija višespratne stambene zgrade, spratnosti Po+Pr+9, prema evropskim propisima za konstrukcije. Analizirana su sva mjerodavna dejstva na konstrukciju, sprovedeno je dimenzionisanje i dati su planovi armiranja karakterističnih konstruktivnih elemenata. Konstrukcija je projektovana za srednju klasu duktilnosti. Analizirani su projektni zahtjevi definisani Evrokodom 8 za zidove za ukrućenje i primarne seizmičke stubove, projektovane za srednju i visoku klasu duktilnosti. Karakteristični zid je dimenzionisan za srednju klasu duktilnosti dok su karakteristični stubovi dimenzionisani za srednju i visoku klasu duktilnosti. Usvojena količina armature je poređena sa količinama dobijenim primjenom domaćih propisa.
ИДЕЈНО РЕШЕЊЕ ОДВОЂЕЊА УПОТРЕБЉЕНИХ И АТМОСФЕРСКИХ ВОДА НАСЕЉА ПАВЛИШ
Authors: Перковић Николина , Stipić Matija Stevan
Published: July 2022

У раду је приказано идејно решење одвођења употребљених и атмосферских вода насеља Павлиш. Представљен је  пример сепаративног канализационог система који чине две канализационе мреже где се једном одводи отпадна вода из домаћинства и индустрије а другом атмосферске воде. Хидрауличка анализа одвођења употребљених и атмосферских вода из предметног насеља извршена је помоћу програмског пакета EPA SWMM 5.1.
REHABILITACIJA KOLOVOZNE KONSTRUKCIJE POSTUPKOM HLADNOG RECIKLIRANJA NA LICU MESTA, PRIMER DEONICE PADEJ-SAJAN l~2.05km
Authors: Jekić Stefan
Published: July 2022

Rad sadrži opis primene i izvođenje postupka za iskorišćenje materijala iz postojeće kolovozne konstrukcije na gradilištu po sistemu „hladne reciklaže“ uz dodatak vezivnih sredstava. Sam postupak je prikazan na praktičnom primeru deonice državnog puta Padej Sajan (L~2.05km).
PROJEKAT VODOVODNE I HIDRANTSKE MREŽE ZA VISOKE STAMBENE OBJEKTE NA PRIMERU „SKYLINE – KULA A“
Authors: Trebovac Vladimir
Published: July 2022

U radu su izložene metode koje se koriste za projektovanje vodovodne i hidrantske mreže  za visoke stambene objekte. Za dimenzionisanje mreže korišćena je Brix-ova metoda, kao i softverski paket EPANET. Na osnovu analiziranja kritičnih tačaka mreža je podeljena po zonama i za svaku zonu određeno postrojenje za povišenje pritiska.
Formulation, Phytochemical Estimation of Active principles by Spectroscopic methods and Comparison of the Poly Herbal Anti-diabetic tablet with The Commercial tablets
Authors: Chauhan Nidhi N. , Mistry Rujuta , Vasava Parul , Mandale Drasti
Published: July 2022

Diabetes mellitus is a group of metabolic disorders characterized by increased glucose levels over a prolonged period. The poly-herbal anti-diabetic tablet was formulated in the laboratory by using herbs of Enicostemma littorale (EL) (Gentianaceae), roots of Aconitum heterophyllum (AH) (Ranunculaceae), rhizomes of Picrorhiza kurroa (PK) (Scrophulariaceae), and fruits of Piper longum (PL) (Piperaceae). Furthermore, Laboratory formulation (LF) and Marketed formulations (MFs) were tested for Phytochemical screening and Qualitative chemical examination. From their result, isolation of active principles, Swertiamarin (EL-1) and Piperine (PN-1), was done and subjected to phytochemical examination by Modern analytical methods like TLC, UV, FTIR. Finally, the quantification and estimation of the afore-mentioned compounds were achieved by HPTLC. SSE of all the four formulations and the chemical tests proved alkaloids, flavonoids, carbohydrates, tannins, phenols and phytosterols. Comparing the data from the melting point, TLC, UV, and IR studies of EL-1 and PN-1 with standard Biomarkers, further calculation of both markers concentrations was done with the help of the calibration equation and the peak area derived from the chromatogram. Study outcomes signify that LF was more potent than MFs for anti-diabetic activity, signifying as a promising natural and safe remedy for the prevention of diabetic complications.
Formulation and In vivo studies of Clopidogrel by Self-Nanoemulsifying Drug Delivery System
Authors: Adella Aparna , Yamsani Shravan Kumar
Published: July 2022

A self-nano emulsifying drug delivery system (SNEDDS) has been explored to improve poorly water-soluble drug clopidogrel’s solubility and dissolution rate. Different formulations were prepared using oil, surfactant, and co-surfactant in varying ratios. From the ternary phase diagram resultant formulations were investigated for clarity, phase separation, drug content, % transmittance, globule size, freeze-thaw, in vitro dissolution studies, particle size analysis, and zeta potential. Based on particle size, zeta potential and dissolution profile, and other studies, F6 was the best formulation of clopidogrel SNEDDS. The particle size of the optimized SNEDDS formulation was found to be 5.2 nm, and zeta potential was found to be -29 mV which complies with the requirement of the zeta potential for stability. The % release from optimized SNEDDS formulation F6 was highest (98.93%) and faster than other SNEDDS formulations and pure drug substance (32%), indicating the influence of droplet size on the drug dissolution rate. FTIR data revealed no physicochemical interaction between drug and excipients. In vivo bioavailability studies were carried out on the optimized formulation (F6), mean time to attain peak drug concentration (Tmax) was 0.5 ± 0.53 and 1.5 ± 0.72 minutes for the optimized and pure drug, respectively, while means maximum drug concentration (Cmax) was 6.77 ± 1.73 ng/mL and 2.10 ± 0.39 ng/mL respectively. AUC0-α and AUC0-t for the optimized formulation were significantly higher (p<0.05) 20.5 ± 2.48 ng.h/mL than the pure drug 6.34 ± 1.73 ng h/mL, respectively. Thus, the results indicate clopidogrel with SNEDDS formulation may be used to improve solubility and dissolution rate for the effective management of heart disease.
Anti-obesity Activity of Extract of Curculigo orchioides Gaertn. Root in High Fat Diet-induced Obesity in Rats
Authors: Tiwari Richa , Gupta Pankaj , Verma Amit K.
Published: July 2022

Curculigo orchioides known as Musali or Talamuli in Ayurveda. Rhizome of C. orchioides is one of a reputed drugs mentioned in the ancient books of Ayurveda and Siddha, Unani and used as an analgesic, anti-inflammatory, spermatogenic, aphrodisiac, immunostimulant, hepatoprotective, anti-asthmatic etc. To investigate the anti-obesity activity of extract of C. orchioides root in high fat diet-induced obesity rats. The five groups in this study were, group I (normal), group II received high fat diet, group III received obese rats given orlistat (50 mg/kg, p.o.), groups IV-Obese rats given extract of C. orchioides root 500 mg/kg,p.o. and groups V-Obese rats given extract of C. orchioides 1000 mg/kg, p.o. On 30th day of experiment, blood glucoses level, lipid profile and biochemical parameter were performed. Body weight of animals was significantly (p < 0.05) maintained in all treatment groups. Progressive maintained blood glucose, lipid profile, and oxidative stress biomarkers were found in all treatment groups during study. The obtained results clearly suggested that C. orchioides possess pronounced anti-obesity potential.
Complete ADMET Profile and Molecular Docking Analysis of Phytoconstituents of Glycyrrhiza glabra and Asparagus racemosus
Authors: Choudhary Balram , Jalwal Pawan
Published: July 2022

The whole study was designed to find out probable anti-diabetic potential of various phytoconstituents of Glycyrrhiza glabra and Asparagus racemosus. The study was further aimed at correlating the relationship between various phytoconstituents of both plants with major receptors playing an important role in diabetes mellitus by in silico and in vitro techniques. For in-silico all the constituents were screened by applying ADMET filters. Selected phytoconstituents were further analyzed through molecular docking. Main four PDB’s 1IR3, 1US0, 2FV6, and 20QV for Insulin receptor, Aldose Reductase, Protein tyrosine phosphatase 1 and Human Dipeptidyl Peptidase IV (DPP4), respectively considered in the study. Molegro Virtual Docker version 6.0 tool employed to carry out the whole study. In contrast to internal ligands Licoriphenone, Hyperoside, Quercetin, Licoarylcoumarin, Glyzarin, and Glabrone represent the best docking results with all the four PDB’s. In in vitro alpha-amylase inhibitory assay, both plants’ combination was examined, and results exhibited that 2:1 GAM and 1:2 GAM have higher inhibitory potential than that of individual extract in contrast standard acarbose. The whole study gives insight that both plants probably have anti-diabetic potential due to the presence of studied biomarkers.
Development of Counseling Information System with Structured Analysis and Modeling in Object Oriented Approach
Authors: Pamuji Agus
Published: July 2022

The need and development of information systems continue to occur. The presence of an information system allows communication between users in counselling services. The development of information systems is a complex concept and has challenges in addition to problems. The main problem is that the requirements for the system are often not explained, making it difficult for designers and system analysts to understand, and adapt the design results to the needs of each user. The motivation of this research is to develop a counselling information system with an object-oriented approach. The method used in the development is the implementation of analysis and building a structured model with the output forming classes and their associations. The final result shows that the class that has been formed reduces the complexity of the system.
Influence of Adding Different Fillers on Polyethylene Properties
Authors: Al-shakoor Abdulla Abd , Majeed Ame’r H. , Ghani Saba A.
Published: July 2022

The aim of this study was focused on the improvement of pouring, mechanical and thermal properties of high density polyethylene using chemically treated kawaline as a filler which is composed of 10% carbamide and 90% kawaline. A composed had been made among the new filler (kawaline-carbamide), alumina and the pure kawaline in improving the latter properties of polyethylene. It was found that all the mentioned properties affect deeply by filler type and its content. Also it was found that the suitable filler is alumina and kawaline –carrbamide in less performance.
Curvature Ductility of Reinforced Concrete Column Sections Under Different strain Rates
Authors: Al-Azawi Thamir K. , Al-Azawi Raad K. , Ibrahim Teghreed H.
Published: July 2022

This paper presents theoretical parametric study of the curvature ductility capacity for reinforced concrete column sections. The study considers the behavior of concrete and reinforcing steel under different strain rates. A computer program has been written to compute the curvature ductility taking into account the spalling in concrete cover. Strain rate sensitive constitutive models of steel and concrete were used for predicting the moment-curvature relationship of reinforced concrete columns at different rate of straining. The study parameters are the yield strength of main reinforcement, yield strength of transverse reinforcement, compressive strength of concrete, spacing of ties and the axial load. The results indicated that higher strain rates improve both the curvature ductility and the moment capacity of reinforced concrete column sections.
Study of Possibility of Using The Reed as Thermal Insulation
Authors: Aslan Sami R. , Mahdi Farouk M. , Ahmed Ahmed H.
Published: July 2022

The present work aimed to study the thermal insulation of the reed so as to be used as a natural thermal insulation due to its availability, mechanical properties and the high porosity of voids. Samples of different thicknesses have been prepared from different diameters of reed. For binding of reed layers white glue and metal wires are used. The thermal conductivity for the specimen is measured by home made box type device in the temperature range 40-90Co and for the different thicknesses. A theoretical model was prepared by using finite element ANSYS program to calculate the thermal conductivity. Comparison of the theoretical and experimental values for thermal conductivity indicates 90% agreement between them. The results showed that the behavior of the thermal conductivity of the reed is similar to the other insulators and its values is in the range 0.039-0.094 W/m Co . By comparing these values with the well known insulator, Stirobore, whose thermal conductivity is in the range 0.0336-0.0433 W/m Co. It could be said that the reed is acceptable as thermal insulation material.
Study The Effect of Industrial Waste (Industrial Water) on The Engineering Properties of Expansive Clayey Soil
Authors: Al-layla Mohammed T. H. , Ahmed Al-kiki Ibrahim M.
Published: July 2022

This Research deals with the effect of industrial waste on the engineering properties of clayey soil .The investigated soil was obtained from (1.0) meter depth Al- Yarmook district in Mosul City. The soil can be described as light brown stiff clay, in organic clay with high plasticity (CH), and it contains (38%) clay size particles (≤ 0.002 mm). The soil was treated with four types of industrial waters, taken from several factories located in Mosul city and from fertilizers factory in Baiji region. The Results, show that the industrial waters caused a little reduction in the liquid limit and Increased the plasticity index, except the fertilizers factors Industrial waters where plasticity index of the soil decrease with increasing the addition of this type of industrial waters. As far as the effect of industrial waters on the compaction characteristics, the result showed that the maximum dry density of the soil increased with the addition of industrial waters and the optimum moisture content decreased. The industrial waters increased the unconfined compressive strength and the shear strength parameters (angle of internal friction (φ’ ) and cohesion (c’)) , except the industrial waters from sugar and yeast factories decreased the angle of internal friction . The study, showed that the swelling percentage and swelling pressure increased with increasing the concentration of industrial waters, except the industrial waters of the fertilizers factory, where the swelling characteristics decreased.The results of consolidation test showed that the compression Index (cc) and coefficient of consolidation (cv) increased when the soil was treated with industrial waters. The results of chemical tests showed that the values of cat ion exchange capacity and organic matter content increased while the (pH- value) decreased for treated soil, except the Industrial waters of fertilizers factory, which caused an increase in the (pH- value) .
A influência de atividades recreativas com pacientes oncológicos: uma revisão narrativa
Authors: Queiroz Bianca Gomes , Mendonça Marcos Antônio
Published: July 2022

Objetivo: Descrever a influência positiva de atividades recreativas no tratamento de pacientes com câncer. Revisão bibliográfica: O tratamento de câncer pode ser uma experiência desagradável e dolorosa para qualquer pessoa, sendo uma fonte de estresse e angústia gerados tanto pelos temores relacionados à própria doença quanto pela convivência com eventuais sofrimentos. A maioria dos pacientes em tratamento quimioterápico possui uma imagem negativa do hospital devido ao uso de medicamentos, procedimentos invasivos, afastamento da rotina e desconfortos gerados pela internação. A presença de atividades lúdicas no processo de tratamento oncológico é de grande importância. Essas atividades possibilitam uma assistência mais humanizada, melhorando a qualidade de vida de indivíduos com câncer, reduzindo os efeitos psicológicos da hospitalização. A humanização do ambiente de tratamento oncológico é uma estratégia de cuidado integral com o ser humano, permitindo uma promoção de saúde com bem-estar biopsicossocial e espiritual, sendo a prioridade a beneficência do doente, considerando a pessoa humana em primeiro lugar. Considerações finais: Dessa forma, atividades recreativas possuem efeitos positivos tornando o ambiente hospitalar mais agradável, por meio de brincadeiras que ajudam as pessoas com câncer a lidar com conflitos e reduzir a angústia originada pela doença e pelo período de hospitalização.
Comportamento sexual e conhecimento acerca das infecções sexualmente transmissíveis entre acadêmicos de medicina
Authors: Lara Thaís Moreira , Neves Ana Cláudia Ferreira , Oliveira Beatriz Pereira , Nogueira Patrícia Pereira
Published: July 2022

Objetivo: Avaliar o comportamento sexual e o conhecimento acerca das Infecções Sexualmente Transmissíveis (IST) entre os acadêmicos do curso de Medicina de uma instituição privada do Rio de Janeiro. Métodos: Trata-se de estudo transversal descritivo e quantitativo, realizado através de aplicação de questionário anônimo contendo 30 perguntas, através do Formulário Google. A análise dos dados foi realizada no formulário da plataforma Google, sendo posteriormente transferida para o Excel. O Teste T de Student foi realizado para verificar presença de relevância estatística, através do valor p < 0,001. O estudo foi aprovado por Comitê de Ética em Pesquisa. Resultados: A amostra contou com 204 acadêmicos, os quais estavam divididos em ciclo básico (46,1%), clínico (33,8%) e internato (20,1%). Destes, 93,6% afirmaram já ter praticado alguma modalidade sexual, dos quais 66% afirmaram o uso de métodos de barreira e 45,6% já utilizaram algum método contraceptivo de emergência. Ao analisar o questionário obteve-se que o nível de conhecimento foi baixo acerca das manifestações clínicas do vírus da imunodeficiência humana e outras IST, como a tricomoníase. Conclusão: Apesar do conhecimento obtido no curso sobre IST e suas formas de prevenção, os acadêmicos ainda apresentam comportamentos de risco e lacunas de conhecimento sobre determinadas doenças.
Asma Pós-Covid: um relato de caso
Authors: Santos Ana Beatriz da Silva , Alves Maria Eduarda Lima , Araújo Danielle Guimarães , Brandão Aline do Nascimento , Leão Alexia Simas Varela , Leão Neto Antonio Targino de Souza , Farias Kelly Soares
Published: July 2022

Objetivo: Relatar o caso de uma paciente que desencadeou um quadro de asma brônquica após a infecção por SARS-CoV-2. Detalhamento do caso: O caso descrito é de uma paciente do sexo feminino, não tabagista, não diabética, 55 anos, enfermeira, parda, sem histórico de asma. A paciente apresentou sintomatologia para Covid-19 e foi diagnosticada em 20/06/2020. Um mês após término dos sintomas, a paciente apresentou indisposição, fadiga e tosse seca, levando-a a procurar a Unidade de Pronto Atendimento (UPA). Posteriormente, com a persistência e intensificação dos sintomas, a paciente procurou um pneumologista. Após avaliação clínica, dos exames de imagem e espirometria, descartou-se diagnósticos clínicos e foi prescrito relvar 100/25mcg por dia. Contudo, não houve efeito. Os novos episódios cursaram com dispneia. Prontamente, houve a busca por um segundo pneumologista. Na avaliação clínica, foram identificados sibilos à ausculta e solicitados exames de imagem. Assim, houve o diagnóstico clínico de asma. Destarte, a dose do Relvar passou para 200/25mcg com resposta terapêutica satisfatória.  Nesse cenário, foi possível avaliar a associação entre SARS-CoV-2 e asma. Considerações finais: Tal discussão é relevante para o âmbito científico dado a escassez de relatos na literatura sobre o desenvolvimento de asma decorrente da infecção por Covid-19.
SARS-CoV-2 e doenças cardiovasculares: uma revisão integrativa
Authors: Santos Yasmin Cristina Garcia , Armi Camila Lourenço , Oliveira Tathiane Souza de
Published: July 2022

Objetivo: Identificar a relação entre as complicações cardiovasculares ao Covid-19, sendo desenvolvidas após infecção. Métodos: Trata-se de uma pesquisa bibliográfica, correspondente ao tipo revisão integrativa. Onde foram considerados pesquisas que abordavam o público jovem e adultos que foram hospitalizados por Covid-19 e desenvolveram complicações cardíacas após a sua recuperação. Dos quais, foram utilizados estudos colhidos através de combinações de descritores em saúde, nas seguintes bases de dados: Biblioteca Virtual em Saúde (BVS), Sistema de Análise e Recuperação de Literatura Médica Online (MedLINE/PubMed), Literatura Latino Americana e do Caribe em Ciências da Saúde (LILACS). Resultados: Foram selecionados 17 artigos, após avaliação na íntegra, os principais achados mostram através evidências científicas com exames laboratoriais e de imagem específicos juntamente com a fisiopatologia na fase aguda da doença, a relação da Covid-19 e as sequelas presentes na pós-infecção. Considerações finais: As complicações cardíacas podem estar associadas aos fatores de inflamação sistêmica, que possibilitam a lesão dos cardiomiócitos, através dos efeitos citotóxicos diretos, além de impactar no processo de ligação aos receptores da ECA2 no tecido cardíaco.
Ships with ‘hitch-hiking’ critters connect Antarctica to the rest of the world
Authors: McCarthy Arlie
Published: July 2022

Ships expose the Antarctica to many kinds of human impacts, including invasive species that cannot cross the rough seas of the Southern Ocean without help. To successfully conserve iconic Antarctic species and environments we need to know where non-native species might come from, and where to look for them in Antarctica
Pemrograman Linier untuk Optimalisasi Operasi Mobilisasi (Studi Kasus pada Operasi Hulu Pengeboran Minyak dan Gas)
Authors: Muhammad Rilly Aka Yogi  , Benny Hamdi Rhoma Putra  , Fitra Lestari
Published: July 2022

[ID] Studi kasus pada penelitian ini diadopsi pada sebuah perusahaan multinasional yang bergerak dalam operasi hulu pengeboran minyak dan gas di Indonesia. Penelitian ini bertujuan untuk mendistribusikan beban dari berbagai fasilitas yang ada pada area pengeboran melalui simulasi optimalisasi mobilisasi Concrete Slab (CS). CS diperlukan dalam operasi pekerjaan persiapan lokasi pengeboran. Kemudian, Pendekatan Simulasi dilakukan menggunakan metode pemrograman linier terhadap kondisi batas antara lain peralatan, durasi, dan jarak melalui fungsi tujuan adalah untuk menekan biaya operasional selama kurun waktu 1 tahun operasi terhadap operasi eksisting pada tahun sebelumnya. Hasilnya ditemukan bahwa terdapat potensial reduksi biaya sebesar 31.36% melalui optimalisasi pada rute operasi. Disarankan penelitian lebih lanjut untuk menentukan total faktur tahunan yang optimal dengan multi variable dalam memobilisasi material, pelat beton (concrete slab), dari satu lokasi ke lokasi lainnya.

[EN] The case study in this study was adopted by a multinational company engaged in upstream oil and gas drilling operations in Indonesia. This study aims to distribute material from various existing facilities in the drilling area through a simulation of optimization of Concrete Slab (CS) mobilization. CS is required in the operation of drilling site preparation work. Then, the simulation approach is carried out using a linear programming method for boundary conditions including equipment, duration, and distance through the objective function is to reduce operational costs for a period of 1 year of operation against existing operations in the previous year. The results found that there is a potential for cost reduction of 31.36% through optimization of the operating route
Estimasi Biaya Pemeliharaan Bangunan Mall di Indonesia (Studi Kasus Kota Palembang)
Authors: Susanti Betty , Foralisa Toyfur Mona , Sho Merri
Published: July 2022

[ID] Di kota besar seperti Palembang terdapat beberapa bangunan mall yang telah berusia belasan tahun dan mengalami kerusakan arsitektur. Salah satu faktor penyebab kerusakan dikarenakan masa pakai bangunan atau yang disebut dengan degradasi. Untuk mengembalikan kondisi bangunan ke keadaan semula dan memperpanjang umur bangunan, diperlukan pemeliharaan dengan melakukan perbaikan atau penggantian komponen bangunan. Pemeliharan bangunan memerlukan biaya yang terencana. Hal yang menjadi fokus penelitian ini adalah pemeliharaan preventif dan corrective. Tujuan penelitian ini adalah menghitung estimasi besaran biaya pemeliharaan bangunan untuk 10 tahun mendatang. Metode Composite Condition Index digunakan untuk menghitung besar tingkat kerusakan bangunan. Penggantian komponen bangunan dilakukan dengan memprediksi kondisi komponen bangunan, sedangkan estimasi biaya pemeliharaan menggunakan metode analisis nilai masa depan. Analisis data menggunakan data kuantitatif dengan variabel penelitian adalah semua biaya pemeliharaan. Hasil perhitungan menunjukkan nilai Indeks Kondisi Bangunan untuk komponen arsitektur bangunan mall adalah 76,24% yang berarti ada 23,76% kerusakan bangunan. Kerusakan terbesar terjadi pada area koridor yaitu sebesar 25,47% dengan Indeks Kondisi Bangunan sebesar 74,53%. Biaya pemeliharaan tertinggi terjadi pada tahun ke-7 sebesar USD 580,854. Biaya ini meningkat 5,8 kali lipat dibandingkan tahun pertama, dengan penggantian material komponen terbesar untuk komponen lantai dan pengecatan dinding.

[EN] In a big city like Palembang, several mall buildings are a dozen years old and have architectural damage. One factor that causes damage is the life of the building or what is called degradation. Maintenance is required to restore the condition of the building to its original state and extend its life. Maintenance is done by repairing or replacing building components. Building maintenance requires planned costs. This research focuses on preventive and corrective maintenance. This study aims to calculate the estimated cost of building maintenance for the next ten years. We used the Composite Condition Index method to calculate the level of damage to the building. Replacement of building components was done by predicting the condition while estimating maintenance costs using the future value analysis method. Data analysis using quantitative data with research variables are all maintenance costs. The calculation results show the Building Condition Index value for the architectural component of the mall building is 76.24%, which means there is 23.76% building damage. The most significant damage occurred in the corridor area, 25.47%, with 74.53% a Building Condition Index. The highest maintenance costs happened in the 7th year of USD 580,854. Compared to the first year, this cost increased 5.8 times, with the most extensive component material replacement for flooring and wall painting components.
Current status of transvaginal mesh implants use in the surgical treatment of stress urinary incontinence and pelvic prolapse
Authors: Shakhaliev Rustam A. , Shulgin Andrei S. , Kubin Nikita D. , Kuzmina Irina N. , Suchkov Denis A. , Shkarupa Dmitry D.
Published: July 2022

The use of synthetic implants in stress urinary incontinence and pelvic prolapse surgery is being actively debated today, not only among experts in the field but also in the media, the patient community, and even in legal and political set. Such response has had a natural effect on the clinical application of the technology. An absurd situation is observed in some countries: the bans imposed by the authorities have directly or indirectly restricted patients' access to the most sophisticated technologies with proven efficacy. This literature review aims to systematize the perspectives of the scientific and regulatory communities in leading countries on the use of transvaginal mesh implants in the treatment of stress urinary incontinence and pelvic prolapse.
Non-invasive diagnosis and non-surgical treatment of endometriosis: A review
Authors: Podzolkova Natalia M. , Fadeev Igor E. , Mass Elizaveta E. , Poletova Tatiana N. , Sumyatina Liliana V. , Denisova Tatyana V.
Published: July 2022

Endometriosis is a hormone-dependent condition occurring in women of predominantly reproductive age. It has an extremely diverse localization, clinical course and outcomes. The need for organ-sparing treatment to preserve and/or restore fertility, the negative effects of radical surgery for endometriosis on ovarian reserve and the effectiveness of assisted reproductive technologies, and the benign nature of the disease, which tends to self-limitation after menopause, lead to the search for effective methods of non-surgical treatment and the need for noninvasive diagnosis of endometriosis. The article presents the current principles of non-surgical management of patients with endometriosis.
Reproductive health of adolescent girls born prematurely: new forecasting opportunities
Authors: Malyshkina Anna I. , Batrak Nataliya V. , Fomina Maria M. , Kiseleva Olga Yu. , Shepelev Dmitrij V.
Published: July 2022

Background. Premature delivery remains one of the most pressing issues in obstetrics.
Aim. To assess the reproductive health of 16-year-old adolescent girls born prematurely to develop an algorithm to optimize its state.
Materials and methods. A total of 180 adolescent girls aged 16 years were evaluated. The study group consisted of 120 adolescents born at a gestational age of 2736 weeks. Subgroup 1 consisted of 18 girls born at a gestational age of 2733 weeks, and subgroup 2 consisted of 102 adolescent girls born at 3436 weeks of gestation. The comparison group consisted of 60 girls born at term. The study material was peripheral venous blood. Hormonal and ultrasonic examination of the internal genital organs were performed.
Results. In the main group vs. comparison group, an increase in serum leptin levels was observed: 9.4 (6.1; 15.5) and 6.9 (4.2; 9.2) ng/ml (p0.01). The leptin blood concentration in subgroup 2 showed a positive correlation with the body mass index (p=0.001). A more frequent increase in the number of antral follicles (10 in each ovary) was recorded in adolescents born prematurely. When assessing the results of correlation analysis, a positive direct correlation between the number of antral follicles and serum leptin concentration in adolescent girls born prematurely (p0.001) was observed. It was found that with a leptin level 15.8 ng/ml, there is an increase in the number of antral follicles, which may be the cause of reproductive disorders.
Conclusion. Premature delivery and its long-term consequences (obesity and metabolic syndrome) contribute to hyperleptinemia, leading to ovarian function suppression in adolescents. Therefore, it is necessary to include leptin level measurement in the algorithm of examining adolescent girls for timely diagnosis and subsequent treatment of possible reproductive disorders.
Current state of COVID-19 in pregnancy
Authors: Sinchikhin Sergey P. , Bragina Galina S. , Parshina Olga V. , Stepanyan Lusine V. , Nasri Onsi , Sinchikhina Ekaterina S. , Berkalieva Asemgul R.
Published: July 2022

There is still a risk of a new wave of coronavirus infection in the general population and among pregnant women. Considering the possible adverse impact of COVID-19 on gestation, it is necessary to update information on the course, prevention, and treatment of the disease in this group of patients. The article includes data from foreign and domestic studies published recently on COVID-19, describing the emergence of new strains of the virus and gestational changes that increase the risk of infection and severe complications, demonstrating the importance of preventive measures. The information provided will contribute to the physicians' awareness, including obstetricians and gynecologists, of COVID-19.
Diagnostic efficacy of transperineal sonography in the verification of pelvic floor muscular and fascial defects. Case report
Authors: Orazov Mekan R. , Khamoshina Marina B. , Gevorgian Dianna A.
Published: July 2022

Pelvic floor insufficiency (PFI) is one of the most common and understudied gynecological diseases. PFI is a major public health problem that will steadily increase due to population aging. The issues of early diagnosis remain unresolved. Physical examination remains the primary method of evaluating PFI, but manual examination alone is not enough to diagnose hidden pelvic floor (PF) defects. Topical verification of muscular and fascial PF defects is necessary to route patients for non-surgical or surgical treatment. 2D/3D transperineal sonography is a non-invasive, simple, and the most common method of imaging PF structures.
Expression of pituitary gonadotropic hormone and sex hormones receptors in endometrial cellular components during menstrual cycle
Authors: Magnaeva Alina S. , Tregubova Anna V. , Tsitrina Alexandra A. , Asaturova Alexandra V. , Shamarakova Marina V. , Tabeeva Guzal I. , Ezhova Larisa S. , Kalinina Elena A. , Bozhenko Vladimir K.
Published: July 2022

Introduction. The main function of the endometrium is to create the optimal environment for embryo implantation, controlled by multicomponent signaling pathways. They are modulated by progesterone and estradiol acting through related estrogen receptors (ER) and progesterone receptors (PR). Alteration in steroid hormone, follicle-stimulating hormone (FSHR), and luteinizing hormone (LGHR) receptor expression are underlying factors in the development of various reproductive disorders. Therefore, understanding the physiological features of receptors expression and localization in tissues is extremely important for a proper comprehensive assessment of the endometrial condition.
Materials and methods. The expression of ER, PR, FSHR, and LGHR in endometrial samples of healthy females from different menstrual periods, who applied for assisted reproductive technologies (ART) due to male infertility, was assessed by immunofluorescence.
Results. The increase in immunoreactivity of ER, PR, FSHR, and LGHR in the glands and stroma of the endometrium is initiated during the early proliferation stage and reaches its maximum during the late proliferation stage. Subsequently, ER expression in the glands and stroma gradually decreases throughout the early and middle stages of secretion; PR immunoreactivity in the stroma and FSHR and LGHR in all endometrial components persists throughout the secretion stage.
Conclusion. The correspondence between the change of the studied receptors' expression and endometrium structural features at different stages of the menstrual cycle was demonstrated. The increased expression of ER, PR, FSHR, and LGHR in the endometrium at the proliferation stage coincides with the growth period of the uterine body mucosa, and the increased immunoreactivity of PR, FSHR, and LGHR during the secretion stage is associated with its decidual transformation and seems to create conditions for successful implantation and embryo development if pregnancy occurs.
Relevance of abnormal uterine bleeding issue in young women and its comprehensive solution considering 2021 Russian Guidelines
Authors: Chernukha Galina E.
Published: July 2022

Abnormal uterine bleeding is a common problem in gynecology. It is a general term to describe menstrual disorders, including frequency, regularity, duration, and bleeding volume in non-pregnant women. Up to 1/3 of women experience this condition during their lifetime. Heavy menstrual bleeding not related to structural abnormality can be a serious health problem for many young women. It has a profound adverse impact on many aspects of their lives and increases the risk of iron deficiency anemia. However, up to half of these women consider the volume of menstrual blood loss normal, and physicians do not ask the relevant questions during counseling. The Russian Clinical Guidelines "Abnormal Uterine Bleeding" provide physicians guide to the assessment, management, and choice of treatment for women with heavy menstrual bleeding.
Scleroatrophic lichen: current view and hypotheses
Authors: Khryanin Alexey A. , Sokolovskaia Asia V. , Bocharova Valentina K.
Published: July 2022

Scleroatrophic lichen (SL) is a chronic inflammatory skin disease of unknown etiology characterized by scar formation. The most frequent localization of SL is the anogenital area. In females, the most common anogenital symptoms are pain, itching, dysuria and dyspareunia. Male patients often present with complaints of a white rash on the penile skin, itching, painful erections and urination, and bleeding or ulceration during intercourse. Although clinical descriptions of SL date back to the mid-20th century, the pathophysiological mechanism remains unclear to this day. The main hypotheses of the pathophysiology of SL are infectious, autoimmune, and chronic irritation theories (occlusive exposure to various irritants, such as urine, leads to chronic skin injury that causes the disease). It is assumed that SL quite often goes undiagnosed for a long time. However, sometimes dermatoses such as eczema in the anogenital area are misdiagnosed by specialists as SL. In this article, the authors discuss in detail the existing hypotheses of SL development, its clinical manifestations, and current methods of diagnostics and therapy.
Meshless sacrocolpopexy for post-hysterectomy vaginal vault prolapse: vascularized flap technique. Case report. Video case**
Authors: Kubin Nikita D. , Shkarupa Dmitry D. , Basos Alexander S. , Shulgin Andrei S. , Labetov Ivan A. , Shakhaliev Rustam A. , Suchkov Denis A.
Published: July 2022

The absence of rigid fixation point, tissue atrophy and multi-compartment defects make post-hysterectomy vaginal vault prolapse a real challenge for the surgeon. The gold standard for treatment of post-hysterectomy vaginal vault prolapse is sacrocolpopexy. Unfortunately, this approach does not allow to perform reliable long-term meshless reconstruction in the anterior and posterior compartments. Moreover, the use of a mesh is associated with the risk of erosion. Aim to show the possibility of replacing a standard mesh with a vaginal flap during laparoscopic sacrocolpopexy. A 60-year-old patient with post-hysterectomy prolapse stage III underwent meshless laparoscopic vaginal-assisted sacrocolpopexy. The duration of the surgery was 105 min (35 min vaginal part and 70 min LS part). Intraoperative blood loss was 55 ml. No intraoperative and early postoperative complications were recorded. According to the ultrasound postvoiding residual was 35 ml, hematomas in the operation area were not visualized. During the exam in 12 months after the surgery, no signs of POP (Aa -2 Ba -3 C -8 Ap -3 Bp -3 tvl 9 gh 4 pb 3), erosion and any pain were detected. The results of the questionnaires were as follows: PFDI-20 22,92, PISQ-12 31 and ICIQ-SF 1. According to ultrasound the volume of residual urine was 0 ml. This approach allows to eliminate completely the risk of erosion and create a unified plastic natural construction from the vaginal cuff and tailored flap.