bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of Red Cell Distribution Width (RDW) in the Diagnosis of Iron Deficiency Anemia
Authors: Purnamasidhi Cokorda Agung Wahyu
Published: April 2020

Background: Iron deficiency anemia (IDA) is the most prevalent micronutrient deficiency in the world. Morphologically, IDA is microcytic and hypochromic as is anemia on chronic disease (ACD) thereby creating confusion on peripheral blood smear examination. Red cell distribution width (RDW) has been proposed to be a more sensitive indicator to establish the possible origin of microcytic hypochromic anemia. Various previous studies have debated the role of RDW in diagnosis of IDA, with no conclusive word on the utility of RDW in diagnosing iron deficiency anemia.Objective. To study the utility of RDW in the diagnosis of IDAMethods: 93 patients with microcytic (MCV<80 fl) anemia were classified into iron deficient (IDA) and anemia on chronic disease (ACD/non-IDA) on the basis of serum ferritin and total iron binding capacity (TIBC). RDW values were obtained on an automated hematology analyzer. Receiver operator curves (ROC) were constructed and the utility of RDW in diagnosis of iron deficiency was studied.Â Results: The mean RDW value was 20.07Â±7.67% in IDA group (57 patients) compared to 17.60Â±3.23 % in the ACD group (36 patients) (p<0.001; CI 95%: 4,14-33,42). At a cut-off value of 17,35%, as obtained from the ROC curve, the sensitivity and specificity of RDW in diagnosis of IDA were 85,96% and 69,44% and a positive and negative predictive value of 81,66% and 75,75% respectively.Â Conclusions: RDW has a good sensitivity for screening diagnosis of IDA among patient with microcytic hypochromic anemia.
The relationship between forced expiratory volume 1 (FEV 1) with 25(OH) vitamin D level and hs-CRP in COPD in H. Adam Malik General Hospital Medan
Authors: Julike Katarina , Tarigan Amira Permatasari , Ganie Ratna Akbari
Published: April 2020

Background: The number of people with COPD according to WHO was increasing to 400 million people by 2020 and half of these occur in Indonesia. The incidence of COPD in Indonesia ranks 5th highest in the world at 7.8 million. COPD was a non-communicable disease that is thought to be closely related to the increasing number of smokers, especially in young age groups. This study aims to determine between FEV1 with 25 (OH) vitamin D level and hs-CRP in COPD patients.Methods: This study was a cross-sectional method conducted in H. Adam Malik General Hospital Medan, from January to June 2018 on 51 COPD patients who were treated at Pulmonology Outpatient Clinic. Spirometry examination, 25 (OH) levels of vitamin D, and hs-CRP was examined. Data were analyzed statistically using SPSS version 16 for windows.Results: Total 51 patients who participated in the study were all male. Based on Pearson Correlation Test, FEV1 value of COPD patients did not show a significant correlation with levels of 25 (OH) vitamin D. While the Spearman Rank Correlation Test shown significant correlation with hs-CRP levels. Anova test results and Kruskal Wallis test on levels of 25 (OH) vitamin D, hs-CRP and Leukocyte counts shown no significant differences with GOLD criteria. Conclusion: The mean FEV1 value of COPD patients, 25 (OH) levels of vitamin D and the number of Leukocytes shown no significant statistical difference, whereas the higher the FEV1value, the lower the hs-CRP.
The difference of nitric oxide (NO) and serum creatinine (SC) levels in hemodialyzed and non-hemodialyzed chronic kidney disease patients at H. Adam Malik Hospital, Medan, Indonesia
Authors: Marpaung Ruslan Dame Hotmauli , Ganie Ratna Akbari , Nasution Alwi Thamrin
Published: April 2020

Background: Chronic Kidney Disease is structural or functional abnormalities of the kidney that last more than 3 months, with or without decreased glomerular filtration rate (GFR) which can be exacerbated by reduced production of Nitric Oxide (NO) or increased serum creatinine level. Hemodialysis is a removal process of solute from the circulation of patients with an impaired renal function to the fluid dialysate by diffusion process through the semi-permeable membrane. This study aims to determine the difference of the Nitric Oxide (NO) and serum creatinine (SC) levels between regular hemodialysis and non-hemodialysis CKD patients.Methods: A cross-sectional study was conducted at Outpatient and Inpatient Section of Nephrology Division, Internal Medicine Department, H. Adam Malik Hospital, Medan during July-August 2017 among 27 respondents who undergone regular Hemodialisa (HD) and 27 respondents in non-Hemodialisa (non-HD) group. The patients that fulfill the inclusion criteria of the study were enrolled. Nitric Oxide examination was carried out by using Chemwell analyzer with a double-antibody sandwich method using Enzyme method -Linked Immunosorbent Assay (ELISA).Results: There was no significant difference of NO-levels between HD groups (1476.14Â± 1431.1 ÂµM) with non HD (1123.06 Â± 1150.83 ÂµM) (P= 0.250). However, there was a significant difference of creatinine level between HD groups (11.8Â±3.26 pg/mL) with a non-HD group (5.71Â±5.03 pg/mL) (P = 0.000).Conclusion: No significant difference of NO levels were found in HD patients and non-HD CKD patients. However, a current study exhibits a significant relationship between SC levels of CKD patients between both groups.
One stage release of circumferential constriction band in upper limb with multiple Z-plasty technique: a case report
Authors: Sanjaya I Gusti Putu Hendra , Hamid Agus Roy Rusli Hariantana , Samsarga Gede Wara
Published: April 2020

INTRODUCTION:Â Congenital constriction band is an uncommon congenital abnormality with multiple disfiguring and disabling manifestations. The widely known management for the correction of congenital constriction band especially in circumferential constriction band is done in a multistage release of constriction band to eluding vascular and lymphatic embarrassment. The purpose of this case report was to present the outcome of one-stage release in terms of safety and aesthetic appearance.Â CASE DESCRIPTION:Women 28 year old came to outpatient plastic surgery clinic presented with circumferential constriction with no functional disability in her right arm since birth. Excision based on design of multiple Z-Plasty is started 2 cm proximal and distal from constricted band. The multiple Z- Plasty flaps are transposed around each other, changing the direction of the constriction band.Â  Postoperatively, the extremity circulation was normal, and no edema was observed. The range of motion is within normal limits and aesthetically acceptable for the patient.Â DISCUSSION: Patterson classified constriction ring syndrome into four types, and type II is the most common. In type II Paterson , there are normal full-layer skin structures and no important nerve or blood vessel was affected so an incision completely encircling an extremity would not interfere with distal circulation and provided strong evidence that one-stage resection of constriction band could be performed. Using multiple Z-Plasty for constriction band release leads to improvement of functional and cosmetic appearance of the defect.Â CONCLUSION: A one-stage release of circumferential constriction band in the upper limb using multiple Z-Plasty is considered as a safe treatment with an aesthetically acceptable result for the patient
The incidence of infection in open cruris fracture grade III A-B treated by external fixation after golden period at Dr. Moewardi General Hospital, Surakarta, Indonesia
Authors: Marpaung Johanes Rizal M , Herunefi Udy
Published: April 2020

Background: The management of open fractures continues to provide challenges for the orthopaedic surgeon. Despite the improvements in technology and surgical techniques, rates of infection and nonunion are still troublesome. Infections in patients with open cruris fracture open after the golden period often occur. There are many risk factors can affect it.Objective: To determine the incidence rate of infection in patients with open cruris fracture treated by external fixation after the golden period at Dr. Moewardi General Hospital from January to December 2018.Methods: The characteristics data of patients were observed by retrospective from the medical record of patients that diagnosed open cruris fracture after the golden period from January to December 2018.Results: In the period of January 2018 to December 2018 there were 55 open cruris fracture with infection incidence rates 72.7% and the most culture result were staphylococcal.Conclusion: the high incidence rates of infection was found in patients with open cruris fractures; therefore,Â  it requires treatment as soon as possible before the golden period.
The prevalence of urinary incontinence in aged women in Peguyangan Village, District of Tag-Tag Kelod, Denpasar, Bali
Authors: Batumalay Diviya , Yuliana Yuliana , Karmaya I Nyoman Mangku
Published: April 2020

Background: Urinary incontinence (UI) is a significant health problem with considerable social and economic impact. Distinguishing between prevalence and incidence of incontinence is important. There are significant variations in the severity and impact of incontinence, and its severity, frequency, and predictability all need to be considered when evaluating its effects on patients, the degree of bother is particularly significant when determining who will need treatment. Incontinence may be a result of bladder dysfunction, sphincter dysfunction, or a combination of both, but large-scale studies are not designed to determine the etiology. Aim: To know the prevalence of UI in aged women in Peguyangan village, Denpasar, Bali.Method: This is cross-sectional descriptive design conducted in Peguyangan Village Denpasar, Bali, in early July 2017. There were 79 of 94 aged women above 65 years involved in the survey using a questionnaire.Result: In young women, the prevalence of incontinence is usually low, but prevalence peaks around menopause, with a steady rise there-after into later life. Although the prevalence of stress and mixed (stress and urge) incontinence is higher than urge incontinence, the latter is more likely to require treatment. In women, moderate and severe bother have a prevalence ranging from about 3% to 17%. Severe incontinence has a low prevalence in young women but rapidly increases at ages 70 through 80.Conclusion: The prevalence is 0.076.
Perbandingan efektivitas teknik modifikasi dan konvensional pada operasi open pyelolithotomy batu staghorn
Authors: Sucipta I Gede Hendra , Oka Anak Agung Gde , Widiana I Gede Raka
Published: April 2020

Background: Open pyelolithotomy for staghorn stone patient management has a high stone-free rate. The disadvantages of open pyelolithotomy include aesthetics and postoperative complications, so a breakthrough to reduce these complications is needed, which can be achieved by doing modified open pyelolithotomy.Objective: To compare the modified and conventional open pyelolithotomy techniques according to the duration of operation, the volume of surgical bleeding, pain, and post-operative drop in hemoglobin (Hb).Method: A quasi-experimental study with twenty-two samples of staghorn stone patients was collected from October 2016 to October 2017. Parametric tests were used as data were normally distributed and homogeneous. The independent t-test was used to compare each measured parameter according to the type of operation. Analysis of covariance (ANCOVA) was used to control the variables of age, gender, and body mass index (BMI).Result: The modified technique had a shorter operating duration than the conventional method (p < .05). The volume of surgical bleeding in the modified technique was lower compared to the conventional technique (p < .05). Pain scores in the modified technique were lower than the conventional technique (p <Â  .05). The drop in Hb levels in the modified technique was lower than the conventional technique (p < .05). Analysis using ANCOVA found that the type of operation has a direct effect on the duration of operation, volume of surgical bleeding, and post-operative pain.Conclusion: The modified open pyelolithotomy technique was more effective than the conventional open pyelolithotomy technique based on the duration of operation, the volume of surgical bleeding, and post-operative pain scale. In this study, it was found that the drop in Hb levels was not directly affected by the type of surgery.
Hubungan prematuritas dengan kejadian sepsis neonatorum yang dirawat di ruang perinatologi dan neonatal intensive care unit (NICU) RSUD Wangaya kota Denpasar
Authors: Amanda Jaya I Gusti , Bikin Suryawan I Wayan , Pramitha Rahayu Putu
Published: April 2020

Background: Premature neonates have an immature immune system due to the lack of IgG antibodies. These antibodies do not cross the placenta from mother to baby at last trimester that can increase the risk of neonatal sepsis. This study aims to determine the relationship between prematurity and the incidence of neonatal sepsis at Perinatology Ward and NICU Wangaya General Hospitals, Denpasar.Methods: This research used analytical observation with cross sectional study design from January-April 2018. The samples involved are 50 neonates, admitted at Perinatology Ward and NICU Wangaya Hospital and fulfilled the inclusion and exclusion criteria. Samples were obtained by using consecutive sampling method and using secondary data from the medical recordResult: 23 samples (46%) premature and 27 samples (54%) were not premature, out of 50 samples as many as 20 samples with neonatal sepsis. From the results of hypothesis testing using the chi-square test, the p-value is 0.005, and the prevalence risk was 2.73.Conclusion: Prematurity is significantly related with the incident of neonatal sepsis at Perinatology Ward and NICU Wangaya Hospital, Denpasar City.
Awareness of breast cancer risk factors and practice of breast self - examination among female students in Medical Faculty, Udayana University, Bali
Authors: Kalithasan Shalini , Rusdi Antara Gede Eka
Published: April 2020

Background: Breast cancer patients generally have low rates of survival rates due to late-stage diagnosis as patients usually present at and late stage because of lack of awareness and ignorance of risk factors.Methods: The objectives of this study are to evaluate the knowledge of risk factor for breast cancers and the practice of breast self-examination among female students in medical faculty at Udayana University. A cross sectional study conducted over a period of one month. 100 female students were volunteered to take part in the survey. The data were analyzed descriptively.Results: A half of the students have moderate knowledge of breast cancer risk factors, and the majority of the students do not practice breast self-examination monthly.Conclusions: It was suggested to students have more concern about relevant education programs that are having around them.Â
Uji korelasi leukosit esterase dan nitrit dengan kultur urin pada infeksi saluran kemih
Authors: Malau Ursula Nauli , Adipireno Purwanto
Published: April 2020

Background: Urinary tract infection (UTI) is a condition where the urinary tract is infected by pathogens, causing microorganisms in urine. The gold standard examination for UTI is urine culture. Urine culture has some weaknessess. It takes around two days to get result and requires quite expensive cost. Leukocyte esterase and nitrite are relatively inexpensive, less-time consuming and easy to do laboratory tests that can detect UTI.Aim: To explore the correlation of leukocyte esterase and nitrite with urine culture in UTI patients.Methods: A cross sectional study of 42 UTI adult patients which treated at Dr. Kariadi hospital Semarang in September until October 2018. Combur dipstick using colorimetry method and urine culture using convensional method. Correlation test analyze using contingency coefficient.Results: The correlation analysis showed there was a positive correlation between urine esterase leukocytes with urine culture (p = 0.044 and r = 0.152) and there was no correlation between urine nitrite with urine culture (p = 0.272),.Conclusion: There was a correlation between urine leukocyte esterase and urine culture and there was no correlation between the urine nitrite to urine culture. However further researches are needed to analyze factors that affecting the UTI diagnostic.
Hubungan antara Chronic Kidney Disease (CKD) dengan hipotiroid di RSUP Dr. Kariadi Semarang, Indonesia
Authors: Dharmanta I Gede Ardy Surya , Samsuria Indranila Kustarini
Published: April 2020

Background: Thyroid hormone in many previous studies have been linked to chronic kidney disease (CKD). There are several interactions between renal dysfunction and thyroid hormones that influence each other. The aim of this study was to see the effect of CKD on the thyroid.Methods: Cross sectional studies on subject data taken retrospectively by looking at medical records on a single center Dr. Kariadi Semarang Hospital during the period 1 June 2017 â€“ 1 June 2018 to then observe the correlation effect of CKD on thyroid hormones by comparing serum urea and creatinine with T3, T4 andTSH.Results: There was a significant correlation of CKD on T3 and TSH levels with ureum (p = 0.020 and p = 0,0,25), and there was a significantly weak correltaion with creatinin (p = 0,081), but there was no significant correlation in T4 (p=0,102; p = 0,108).Conclusion: The results of this study can be concluded that there is a significant correlation between Chronic Kidney Disease (CKD and hypothyroidism, especially the correltation effect of T3 with ureum and creatinine, and TSH with ureum.
Analisis rasio netrofil limfosit dan rasio platelet limfosit terhadap penanda gangguan ginjal pada penyakit systemic lupus erythematosus di RSUP dr. Wahidin Sudirohusodo tahun 2017-2018
Authors: Lauddin Evi Andriyani , Nurulita Asvin , Muhadi Darwati
Published: April 2020

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that causes damage to several organ systems including the kidneys. The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) continue to be developed as a marker of SLE disease activity. This study aimed to assess NLR and PLR for markers of kidney disorders in SLE.Method: A retrospective study evaluated NLR and PLR with routine urine results including proteinuria, hematuria, and casts from 40 subjects of SLE patients at Dr.Wahidin Sudirohusodo Hospital Makassar from July 2017 - July 2018. Descriptive statistical analysis, frequency distribution and Mann-Whitney statistical test.Results: NLR values were significantly higher in positive hematuria than negative hematuria, which was 7.44 compared to 3.80 (p <0.05).Conclusion: A significant relationship between increased NLR values and hematuria can be used as a marker of early occurrence of lupus nephritis even though no manifestations or signs of other kidney disorders are found.
Hubungan suami perokok terhadap bayi berat lahir rendah pada neonatus di ruang Perinatologi RSUD Wangaya kota Denpasar
Authors: Grandinata Soeseno William , Bikin Suryawan I Wayan , Widiasa A.A. Made
Published: April 2020

Background: Low birth weight babies (LBW) are still a problem. The causes of LBW are multifactorial, one of which is exposure to toxic substances (cigarettes). Exposure to cigarette smoke can disrupt fetal development during the womb. Based on studies, active and passive smokers have almost the same level of risk. This study aimed to find out about a smoker's husband as a risk factor for the occurrence of low birth weight babies in neonates at Perinatology Room of Wangaya Hospital, Denpasar.Methods: Analytical observational research with case-control research design. The study sample was all neonates who were treated in the Perinatology Room of Wangaya Hospital from May to August 2018 and fulfilled the inclusion and exclusion criteria. Based on the calculation of the sample size, 72 neonates were obtained. The sample is determined by consecutive sampling. In this study, data were obtained from medical records (documentation) and questionnaires.Result: Samples were divided into two groups, namely the case group and controls where each group consisted of 36 samples. As many as 23 of the 36 neonates who were smokers' husbands suffered from low birth weight babies (63.88%), while 13 others did not suffer from low birth weight babies (36.11%). The results of hypothesis testing using the chi-square test, the value of p = 0.03 (p < 0,05, OR = 2,78, CI = 0,091-0,267).Conclusion: Smokers' husbands were significantly a risk factor for the occurrence of low birth weight babies in neonates who were treated in the Perinatology room of Wangaya Hospital, Denpasar.
Perbedaan stress kerja pada perawat di ruang unit gawat darurat dengan perawat di ruang rawat inap Rumah Sakit â€œSâ€ di Kota Denpasar tahun 2017
Authors: Putri Mahastuti Putu Dharma , Muliarta I Made , Adiputra Luh Made Indah Sri Handari
Published: April 2020

Introduction: Job stress can be interpreted as a demand or stressor that can cause a complaint or stress caused by work. This study was conducted to know the difference of job stress that happened at Emergency Room and inpatient ward at Sanglah Hospital Denpasar. Method: This study used cross sectional analytic design and the data was analyze from the job stress questionnaire that was validated. Questionnaires were given to nurses that working in the emergency room and inpatient ward at Sanglah Hospital Denpasar. The samples size is 116 subjects. Result: The result is 7 nurses at the emergency room (12.1%) and 29 inpatients (50%) had mild stress, 33 ER nurses (56.9%) and 25 inpatients (43.1%) experienced moderate stress meanwhile, at 18 ER nurses (31%) and 4 inpatients (6.9%) had severe stress. Based on statistical test to find out the difference of work stress using Mann-Whitney test, the result of Mann-Whitney U value is 841.0 and p value is 0.000. So it can be concluded that p valueÂ  <0.05. Conclusion: Thus, there is a significant difference in the level of work stress between nurses who served in the emergency room with inpatient care.
Impact of depression on the academic performance of international students in Udayana University
Authors: James Jacintha , Sawitri AA. Sagung , Ariastuti Luh Putu , Aryani Putu
Published: April 2020

Background: Depression is a mental disorder that affects an individualâ€™s mood and emotion. Depression is very common among the students. In this study, the impact of depression, especially on the academic performance of students who are abroad, studies along with the risk factors of depression.Aim: The study aims to know the relationship between depression and the academic performances of international students studying abroad. Â Method: In this analytic study, a cross sectional method was being used. This method is being used to analyze the relationship between the factors that influence the academic performance and also to investigate the relationship between depression and academic performance of the students.Result: As for the residence factor, the student who was lived alone performed better in academic. For the method of study factor, the student who conducts independent learning performs well in academic whereas for the factor back to Malaysia in a year, the students who go back to Malaysia less than or twice a year performs better in their academic. As for the family support factor, students who have good family support obtain good results in academic performance, but for factor family financial support, students with inadequate financial support obtain good results in their academic.
Kondisi optimal PCR untuk mendeteksi gen FimH isolat klinis Escherichia coli penyebab infeksi saluran kemih
Authors: Zharaswati Prisela , Budayanti Ni Nyoman Sri , Fatmawati Ni Nengah Dwi
Published: April 2020

Background: Urinary tract infection is one of the most common infectious diseases and the second most common infection after respiratory tract infection. Bacteria are the most common cause of urinary tract infections in more than 95% of cases. Escherichia coli is the most common bacteria that found in 80-90% of cases of urinary tract infection. The critical virulence factor of Escherichia coli is the type 1 fimbriae with the adhesion subunit, fimH, plays an essential role in the pathogenesis of urinary tract infection.Aim: The research aims to obtain the optimal condition of PCR in detecting the fimH gene with modification of annealing temperature in the PCR process.Method: This study used a sample of fimH DNA genes from clinical isolates of E. coli causing UTI. The second PCR used an annealing temperature of 57Â°C and a third PCR using an annealing temperature of 64Â°C. The electrophoresis results are then viewed with an ultraviolet transilluminator. Result: The optimization finding showed that the annealing temperature of 52 Â°C, 57 Â° C, and 64Â°C could detect the fimH gene where the higher the temperature used by Tm, the less the specificity produced.Conclusion: The optimum annealing temperature of PCR to identify the fimH gene from E.coli causes the UTI is in the temperature of 64Â°C with better specificity than of 52Â°C. The annealing temperature of 64Â°C indicates the lowest specificity.
Proporsi depresi pada penderita diabetes melitus tipe 2 di RSUP Sanglah Denpasar
Authors: Krisnawan Gede Aditya Ersa , Aryani Putu , Sari Komang Ayu Kartika
Published: April 2020

Introduction: Over 285 millions of people in 2010 in the world live with diabetes mellitus type 2 (DMT2). In Indonesia based on Riskesdas 2013, 2.45 millions of people live with DMT2 or around 1.5% of Indonesiaâ€™s total population. One of the disease causded by DMT2 is depression. 30% people with DMT2 has also experience depression. Depression in Indonesia based on Riskesdas 2013 has 19 millions of people suffering from it or 11.6% of Indonesiaâ€™s total population.Method: This research was a descriptive study with cross-sectional approach. The subjects was 51 patients diagnosed with diabetes melitus type 2 and did the follow-up in Diabetic Centre of RSUP Sanglah from October-November 2017.Data for this research was acquired Â from interview using Zung Self Depression Scale (ZSDS).Result: The results showed 78.9% sample which experience depression higher in women (80.0%), the unemployeed subject (88.6%), medium educational degree (86.2%), duration of illness >5 years (87.5%), the usage of insulin (81.0%), and patient with complication history (78.8%).Conclusion: Higher depression was found in patients with DMT2 with female gender, not working, disease duration> 5 years, history of insulin use, and had a history of complications. The proportion of depression in DMT2 patient was high, thus further research on relation between depression and DMT2 is necessary to conduct
Hubungan antara obesitas dan insiden kanker kolorektal di RSUP Sanglah tahun 2016-2017
Authors: Trisuladara Anak Agung Sagung Mirah , Sueta Made Agus Dwianthara , Adnyana Made Suka
Published: April 2020

Introduction: Colorectal cancer is the third malignant disease in Indonesia. Obesity is one of the risk factors related to colorectal cancer. This research aims to role out relationships between obese and age to the incidence of colorectal cancer at Sanglah General Hospital.Method: Study design using case-control analytic model, covering 274 samples, divided into the group of colorectal cancer (137 persons) and non-cancer samples (137 persons). Secondary data were used for analysis obtained from medical records in year period of 2016-2017 at Sanglah General Hospital. Data were analyzed using Chi-square analysis and risk estimate model.Result: The result showed that the majority of colorectal cancer patients were male (53.3%), meanwhile for non-cancer patients were female (50.4%). The average age of colorectal cancer patients was 54 years old while 42 years for non-colorectal cancer patients. Based on the BMI groups, majority of cancer colorectal patients (62%) belongs to obese, while only 39.4% for non-colorectal cancer patients. Result of analysis showed that there is significant relationship between obese and the incidence of colorectal cancer (p value <0.001), with the risk increase of prevalence by 1.588 times higher for those patients with BMI â‰¥23.00 kg/m2 (95% CI 1.235-2.040). Result from the Chi-square test also indicated that there is significant relationship between age above 40 years and the incidence of colorectal cancer (p value <0.001).Conclusion: It can be concluded that there is significant relationships between obese and age above 40 years to the incidence of colorectal cancer.
The influence of light physical activity on scale of pain in elderly with knee osteoarthritis
Authors: Subramaniam Prasenah , Astika Nyoman , Mariadi Ketut
Published: April 2020

Background: Osteoarthritis (OA) is a collection of mechanical variations of joint thinning, including the articular ligament and the subchondral bone.Aim: This study aims to find out how some light physical activity correlates with the pain scale among elderly with knee osteoarthritis and also to find out whether light physical activity in the elderly helps reduce pain in knee osteoarthritis.Method: This research is a descriptive cross sectional study. The sample in this study was elderly people aged 50 years and above with a total of 70 samples were selected using multistage random sampling technique located in Badung Market, Kumbasari Market, and Renon Field. Data were obtained by interviewing respondents who previously provided informed consent using structured questionnaires. The degree of pain caused by osteoarthritis was measured using The Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and the total score.Results: Distribution of sex within samples found that women (54.3%) and men (45.7%). Researchers found that the mean age of respondents was 61.2 (SD + 3.75) years. The total number of respondents who have exercise habits is 52.9%. The average WOMAC score was 23 (SD +2,319) with a minimum score of 18 and a maximum of 27. Respondents with WOMAC score <23 were 52.9% whereas respondents with WOMAC score> 23 were 47.1%. Cross-tabulation results showed 97.3% of respondents with a WOMAC score <23 had exercise habits.Conclusion: The exercise habits of the elderly with knee osteoarthritis can reduce pain when measured using a 0-4 scale and the WOMAC pain scale.
Perbedaan rerata kadar protein-C pada sepsis neonatorum dengan kultur positif dan negative di RSUP H. Adam Malik Medan tahun 2018
Authors: Nugraha Jeffry , Loesnihari Ricke , Tjipta Guslihan Dasa
Published: April 2020

Background: First ten months from conception is a period of susceptibility to infection. Diagnostic testing for disease must be conducted as quickly as possible for antimicrobial administration. Blood culture, the 'gold standard' for diagnosis, is full of shortcomings. Decreasing protein C levels are characteristic of sepsis due to an increase in consumption, degradation, or decreased synthesis, so that the onset of protein C deficiency may occur before the diagnosis of sepsis.Aim: The study aimed to determine the difference in mean serum C protein levels in septic neonatorum in which positive cultures compared with negative culturesMethods: The sample in this study were septic neonatorum patients in the perinatology unit of H. Adam Malik General Hospital Medan by consecutive sampling technique. The blood was incubated in BACTEC 9050 and identified with gram staining, gram-positive identified by catalase, coagulase and MSA tests, while gram-negative with API 20E. Protein C was examined with Coatron A4. A bivariate analysis determined differences in protein C in septic neonatorum with positive and negative cultures.Result: The prevalence of positive culture sepsis was 36.1%. The most common pathogens were Staphylococci epidermidis (19.4%). There was no significant difference in protein C levels between the septic neonatorum with positive and negative cultures (p = 0.166). Positive culture sepsis is a risk factor associated with protein C decreasing with p = 0.011. Positive culture sepsis had a higher risk of reducing protein C levels by 7.536 times compared to negative culture sepsis.Conclusion: There were no significant differences in protein C levels between septic neonatorum with positive and negative cultures, but sepsis was significantly associated with a decrease in C protein levels.
Analisis Corrected Count Increment (CCI) pada penderita post transfusi trombosit apheresis di RSUP Dr. Wahidin Sudirohusodo, Makassar, Indonesia
Authors: Asri Lisdiana Amin , Juliani Sri , Muhiddin Rachmawati
Published: April 2020

Background: Platelet refractoriness is a problem in the implementation of platelet transfusion. It is a lack of increased platelets after platelet transfusion. This study aimed to analyze the increase in platelet counts of patients who received apheresis platelet transfusion by using Corrected Count Increment (CCI) formula at Dr. Wahidin Sudirohusodo General Hospital Makassar.Methods: This was an observational cross sectional study with 242 thrombocytopenia patients. The success of platelet transfusion was calculated using the CCI formula with CCI values after transfusion of 4.5 x 109/L at 24 hours post transfusion. Statistical analysis used chi square, t-independent, and spearmenâ€™s correlation test, with significant test results if p-value was < 0.05.Results: An average increase of platelet counts was 28.5 x 109/L. Successful thrombocyte transfusion was found in 107 subjects (44.2%) and unsuccessful in 135 subjects (55.8%). The proportion of successful transfusion was found to be higher in men (45.5%) than women (43.2%), however, it was not significant (p > 0.05). There was a significant relationship between young age and successful thrombocyte transfusion (p < 0.001). Unsuccessful transfusion rate was high in cases of malignancy, infection, bleeding, and metabolic disease (p < 0.05).Conclusions: There was a significant negative correlation between age and CCI, older age presented lower value of CCI. Characteristics of disease affected the successful of apheresis thrombocyte transfusion.
Nilai rasio netrofil limfosit dan rasio trombosit limfosit pada pasien chronic kidney disease sebelum dan setelah hemodialisa
Authors: Nelly Nelly , Widaningsih Yuyun , Mangarengi Fitriani
Published: April 2020

Background: CKD is a world health problem with an increasing incidence, having a poor prognosis and requiring expensive treatment costs. Cardiovascular disease is the cause of high mortality rates in CKD patients due to inflammation. Neutrophil to lymphocytes ratio (NLR) and platelet to lymphocyte ratios (PLR) are considered as inflammatory markers that are cheap, fast and easily calculated from the routine blood examination. This study aimed to know the value of RNL and RTL in CKD patients before and after HD as the initial marker of inflammation. Method: Eighty-eight patients with CKD were divided into three groups before HD, after the first HD, and after the third HD. The neutrophil-lymphocyte ratio and platelet-lymphocyte ratio are calculated based on the results of routine blood tests. Data distribution was tested with Kolmogorov-Smirnov and analyzed by appropriate data testing.Results: RNL and RTL values in CKD patients after HD increased compared to before HD (p <0.05). There is a weak correlation between RNL values and serum urea levels. However, the RTL value only correlates with urea before hemodialysis.Conclusion: There are differences in RNL and RTL values in CKD patients before HD, after the first HD and third HD. There is a correlation between the RNL value and the state of uremia that is aggravated by HD
Analisis amilase serum pre dan post-endoscopic cholangiopancreatography pada penderita kanker pankreas tahun 2017-2018 di RSUP Dr. Wahidin Sudirohusodo, Makassar, Indonesia
Authors: Umar Nunung Meisari Indah , Nurahmi Nurahmi , Pakasi Ruland DN
Published: April 2020

Background: Pancreatic cancer is a cancer of the thirteenth sequence of events worldwide and the fourth most common cause of death by some cancers. Amylase levels can increase if there is damage to pancreatic cells. Therapeutic ERCP procedure is expected to reduce amylase levels that are elevated in pancreatic cancer. This study aimed to evaluate the preand post ERCP serum amylase in pancreatic cancer patients.Method: Observational retrospective using data from pancreatic cancer patients in January 2017 - January 2018 at the Laboratory of Clinical Medicine and Mechanical Installation of Dr. Wahidin Sudirohusodo Hospital, Makassar. Data were analysed using SPSS version 22 software for windows.Results: Total of 39 pancreatic cancer subject aging 31â€“93 years were found, most of them were women. PreERCP amylase levels with a value of 167.5 Â± 235.6 as against of 137.5 Â± 159.4 in post ERCP. Some subject showed a decreased level and some showed an increased level. Statistical tests did not show significant results (Wilcoxon-signed rank test p> 0.05).Conclusion: Serum amylase levels that have increased therapeutic post ERCP can be information for clinicians to pay more attention to ERCP cannulation techniques in order to avoid post ERCP complications.
Gambaran hasil pemeriksaan faal hemostasis pada penderita Diabetes Melitus tipe-2 (DM-2) di RSUP Sanglah, Bali, Indonesia
Authors: Pramudita Nyoman , Mulyantari Ni Kadek
Published: April 2020

Background: Diabetes Mellitus Type II (DM-2) is a type of hyperglycemic state which is related to metabolic disorders caused by mutations in several genes. Faal hemostasis is a function of the body that aims to maintain the blood that has been thinned so that the blood flowing in the veins and could be interfere with blood glucose level. This study aims to describe the faal hemostasis examination in patients with DM-2 in Sanglah Hospital.Methods: A cross-sectional study was conducted among patients with diabetes mellitus type II (DM-2) who were hospitalized in Sanglah hospital at the period started from January 1st to December 31st, 2015. The sample selection were using consecutive sampling with a total of twenty eight samples. Data were analyzed using SPSS version 17 for WindowsResults: The study found that males were predominant in this study (53.6%). In addition, 51-60 years age group were also predominant (39.3%), following by history of hypertension (82.1%), 10-14 seconds of Prothrombin Time (PT) (67.9%), 30-40 seconds of Activated Partial Thromboplastin Time (APTT) (53.5%), and bleeding time (BT) > 1.3 minutes (67.9%).Conclusion: Several faal hemostasis assessments were predominant in patients with DM-2 such as 10-14 seconds of PT, 20-40 seconds of APTT, and bleeding time more than 1.3 minutes.
Teknik two step-cutaneous plasty shaft Penis dengan scrotal skin pada kasus parafinoma penis: laporan kasus
Authors: Pratama Putu Kurnia Darma , Sanjaya I Putu Gde
Published: April 2020

Background: Penile injection of paraffin is one of procedure that people think can increase penile size. Nevertheless, many people do not know if paraffin injection causes significant adverse effects such as penile paraffinoma. A surgical procedure by wide excision of skin and subcutaneous tissue infiltrated by paraffin continued with appropriate phalloplasty could be done as definitive therapy with the good aesthetic and functional result. This case report aims to present penile parafinoma or sclerosing lipogranuloma due to subcutaneous penile injection of paraffin, its management and the result after surgical procedure.Case: A 40-year-old man came to the Urology Polyclinic, Mangusada Badung Regional Hospital who presented with penile swelling and pain for 3 days. There was a history of subcutaneous penile injection of paraffin about one-year ago by non-medical personnel. On examination of genital organ, there was swelling on entire penile skin with tenderness and induration. A surgical procedure was performed using a two-step cutaneous plasty technique with scrotal flaps on the shaft of the penis. After two months, the surgical procedure gave an excellent penile aesthetic and functional result.Conclusion: Penile parafinoma is a lipogranulomatous inflammatory reaction due to injection of paraffin substance, which cases are still found today, especially in Indonesia. Reconstructive surgery is the definitive therapy to overcome aesthetic or functional problems.
Administration of sildenafil citrate not able to reduced hs-CRP on erectile dysfunction patient at Doctor Soetomo Hospital, Surabaya, Indonesia
Authors: Pramesemara I Gusti Ngurah , Marthasari Rossy Sintya , Octarina Rezia , Silalahi Ahmad Ricardo Syukur , Hartono Judie , Tanojo Tjahjo Djojo
Published: April 2020

Background: Phosphodiesterase type-5 (PDE5) inhibitors was the first choice for the oral treatment of erectile dysfunction because of its ability to prevent endothelial dysfunction and restored erectile function properly. However, the inflammatory parameter such as hs-CRP can be used to assess the performance of PDE5 inhibitors as well as clinical questionnaires, IIEF-5, and EHS. So that, this study aims to determine the effect of PDE5 inhibitors administration such as sildenafil citrate 50 mg per day can decrease the value of hs-CRP, as well as increased the IIEF-5 and EHS at Dr. Soetomo General Hospital.Methods: A true clinical experimental studies used pretest and posttest control group design were carried out among 20 patients during 4 weeks. In the next 2 weeks, the crossover was conducted among respondents for the washout period whereas divided into 2 groups, control (K1 and K2) and treatment (P1 and P2). Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 16.0 software for Windows.Results: The average age of group K1 and P2 was 51 Â± 12.07 years old whereas 48.60 Â± 15.40 years old in group P1 and K2. The research was conducted in Andrology Clinic of Doctor Soetomo Hospital in Surabaya during June to November 2017. The research data were not normally distributed, then analyzed by two-tail T-group tests and Wilcoxon test at significance level Î±=0.05. The results showed that PDE5 inhibitors did not decrease the hs-CRP significantly (p>0.05), but increased EHS (p<0.05) and increased IIEF-5 (p<0.05) significantly.Conclusion: This study concluded that the administration of sildenafil citrate per day by oral increased the EHS and IIEF-5, but not able to reduced hs-CRP in patients with erectile dysfunction significantly.
Study of knowledge in diarrhea and personal hygiene among students below 10 years old in SD Santo Yoseph 2, Denpasar in 2016-2017
Authors: Manogaran Karthigeyan , Utama I Made Gede Dwi Lingga , Gustawan I Wayan
Published: April 2020

Background: The lack of basic knowledge of diarrhea and also poor self-hygiene might be the risk factors of diarrhea.Aim: The study aims to identify the knowledge of diarrhea and personal hygiene among student below 10 years old in SD Santo Yoseph 2, Denpasar, Bali. Method: This cross sectional study was conducted on students below 10 years old in SD Santo Yoseph 2, Denpasar. Fifty students participated in this study, and they were divided into two groups. Of total study participants, 25 were from 8 years old, and 25 were from 9 years old. They were asked to fill up a self-administered questionnaire. The variables assessed were their knowledge of diarrhea (definition, etiology, risk factors, sign and symptoms, complications, treatment and management, and prevention) and application of personal hygiene.Result: About 34% of 50 students below 10 years old in SD Santo Yoseph respectively had good knowledge of diarrhea. However, 66% of students had very less knowledge about diarrhea where they get below. For the application of personal hygiene, 24% of students managed to get a good score while 74% of them failed to get a good score. The vast majority had adequate knowledge of the definition of diarrhea. At the same time, the majority of the students was unable to know that dehydration is the complication of diarrhea due to the loss of a large amount of water and salt in the body.Conclusion: Though the overall knowledge in diarrhea and application of hygienic lifestyle among the students were poor, few minorities of the students had a good understanding of both these variables. There is a strong need for early childhood education about knowledge in diarrhea and personal hygiene in school level itself as a method of prevention.
Profil dermatitis seboroik pada pasien di Poliklinik Rawat Jalan Kulit dan Kelamin RSUD Wangaya Denpasar periode Oktober 2017-Oktober 2018
Authors: Elisia Elisia , Dalem Pemayun Tjokorda
Published: April 2020

Introduction: Seborrheic dermatitis is a chronic superficial skin disorder occurs in 2-5% of population with the symptom of erythematous plaque with slightly yellowish scaling and without clear border, it caused by multifactorial etiopathogenesis includes sebaceous gland secretion, Malassezia fungi colonization, and immune response. This disease is higher in rich sebaceous gland area, is mostly found in the face, upper trunk, and intertriginous (inguinal, inframammary, and axilla).Aim: This study aimed to know the profile of seborrheic dermatitis patients in dermatovenereology outpatient clinic of Wangaya General Hospital in October 2017-October 2018 period.Methods: This study is a retrospective study based on the number of cases, sex, age group, location of lesion, and type of treatment from patient medical records of dermatovenereology outpatient clinic in Wangaya General Hospital in 2017-2018 period.Results: Seborrheic dermatitis mostly found in men (64,2%) with the adult age group is the highest number (77,6%). This disease often affected the face area in 36 patients (53,7%). The most frequent treatment used was anti-inflammation agent in 41 samples (61,2%). In this study, anti-inflammation used were topical corticosteroids (64,2%), there were betamethasone for adults and hydrocortisone for children.Conclusion: Seborrheic dermatitis were mostly found in male, occurred in the age group â‰¥35 years. The location of lesion is higher found in face area and mostly treated with corticosteroidÂ
Analisis nilai diagnostik C-reactive protein pada pasien pediatrik dengan apendisitis di RSUP Dr. Wahidin Sudirohusodo, Makassar, Indonesia
Authors: Hermawan Hermawan , Muhadi Darwati , Samad Ibrahim Abdul
Published: April 2020

Background : Acute appendicitis associated with acute phase reaction is the most prevalent disease which requires emergency surgery. Its delayed diagnosis and unnecessarily performed appendectomies lead to numerous complications. In our study, we aimed to detect the role of C-reactive protein (CRP) in the exclusion of acute and complicated appendicitis and diagnostic accuracy in pediatric age group.Methods : A retrospective analytic observational study with cross-sectional design was performed on 69 children with definitive appendicitis. Appendectomized patient groups were constructed based on the results of histopathological evaluation. The area under a receiver operating characteristic (ROC) curve (AUC) was performed to examine diagnostic accuracy.Results : Based on cut-off values of â‰¥ 22,6 mg/dL for CRP level, diagnostic parameters were as follow : sensitivity 97,4%, specificity 80,0%, PPV 97,4%, NPV 80,0%, and diagnostic accuracy 89,9%. AUC values were 0,98 (95% CI 0,96 â€“ 9,99) for CRP.Conclusion : For complicated appendicitis, CRP has the highest degress of diagnostic accuracy. The diagnosis appendicitis should be made primarily based on clinical examination, and obviously more specific and systemic inflammatory markers are needed. Cut-off values of CRP â‰¥ 22,6 mg/dL provides discrimination values for complicated appendicitis.