bluuebunny/crossref_metadata_2025 huggingface dataset:
One Disease, Two Approaches. Acute Post-Streptococcal Glomerulonephritis – A Case Report of Two Young Patients
Authors: Lungu Tudor , Nagy Kinga Krisztina
Published: August 2021

Objective: Acute post-streptococcal glomerulonephritis (APSGN) is the most studied immune-mediated glomerulonephritis, being caused by streptococcal infections such as pharyngotonsillitis or skin infections (impetigo, erysipelas). Globally it is the main form of glomerular suffering among pediatric patients, especially between the ages of 3 and 15, but in the developed countries, the incidence of this condition has decreased significantly in the last decades. The majority of the medical literature indicates that the treatment in such a disease is symptomatic (the major goal being controlling of the edema and hypertension) associated with antibiotics for streptococcal infection. Due to some situations where antibiotic treatment cannot be administered, this case report hypothesized that homeopathy is a possible alternative treatment method for conventional therapy. We presented two cases diagnosed with APSGN: a nine-year-old boy treated homeopathically at home and a three-year-old girl treated conventionally during hospitalization. Analyzing the two cases, we observed that the patients were cured regardless of the therapeutic method approached. This aspect has an advantage in situations where there are limitations in the administration of allopathic treatment. According to homeopathic understanding, the success rate is higher when there are clear homeopathic symptoms for choosing the right remedy. Many more cases and much more research is needed to conclude that classical homeopathy can be a treatment option for this pathology. In conclusion, it is important to find a personalized therapy (allopathy or homeopathy) for each patient that will bring the maximum benefit, depending on the particularity of the case
A retrospective comparative cohort study on the routine pre-engraftment use of granulocyte colony-stimulating factor in allogeneic hematopoietic stem cell transplantation
Authors: Aydin Muruvvet Seda , Cengiz Esra , Gunes Ahmet Kursad , Ucar Mehmet Ali , Ceran Funda , Ozet Gulsum , Dagdas Simten
Published: August 2021

Objective: Myeloid growth factors have been often used in allogeneic hematopoietic stem cell transplantation settings. There are some controversies about increased graft versus host disease, relapse, and delayed platelet engraftment with those growth factors in the pre-engraftment period. In this study, we aimed to compare the transplantation outcomes of allogeneic hematopoietic stem cell transplantation recipients according to their myeloid growth factor support status.

Materials and Methods: Sixty-seven adult acute myeloid leukemia/myelodysplastic syndrome and acute lymphoblastic leukemia patients who underwent allogeneic peripheral blood stem cell transplantation from HLA-identical matched sibling donors were analyzed retrospectively. All-cause mortality at day 100, day 180, and at 1-year were the primary outcome measures. Secondary outcome measures were the engraftment kinetics, length of hospital stay, and graft-versus-host disease incidences.

Results: Growth factor supported group was younger (p=0.001), and the first complete remission status at transplantation was seen more compared to the unsupported group (p=0.04). Myeloablative conditioning was used more in growth factor supported group (p=0.004). Faster neutrophil engraftment (p=0.008) and delayed platelet engraftment (p=0.022) were seen in growth factor supported group. Graft-versus-host disease, relapse incidences, and all-cause mortality at day 100, day 180, and at 1-year were not different between groups. Steroid-resistant graft-versus-host disease was the only factor related with relapse (OR: 0.196, p=0.043).

Conclusion: This real-life study shows colony-stimulating-factors are safe in HLA-identical sibling allogeneic hematopoietic stem cell transplantation. Further prospective randomized controlled studies for different stem cell sources, different donors, and different conditioning and graft-versus-host disease prophylaxis regimens are mandatory.
Blockchain-Enabled Federated Learning on Kubernetes for Air Quality Prediction Applications
Authors: Benedict Shajulin , Saji Deepumon , P. Sukumaran Rajesh , M Bhagyalakshmi
Published: August 2021

The biggest realization of the Machine Learning (ML) in societal applications, including air quality prediction, has been the inclusion of novel learning techniques with the focus on solving privacy and scalability issues which capture the inventiveness of tens of thousands of data scientists. Transferring learning models across multi-regions or locations has been a considerable challenge as sufficient technologies were not adopted in the recent past. This paper proposes a Blockchain- enabled Federated Learning Air Quality Prediction (BFL-AQP) framework on Kubernetes cluster which transfers the learning model parameters of ML algorithms across distributed cluster nodes and predicts the air quality parameters of different locations. Experiments were carried out to explore the frame- work and transfer learning models of air quality prediction parameters. Besides, the performance aspects of increasing the Kubernetes cluster nodes of blockchains in the federated learning environment were studied; the time taken to establish seven blockchain organizations on top of the Kubernetes cluster while investigating into the federated learning algorithms namely Federated Random Forests (FRF) and Federated Linear Regression (FLR) for air quality predictions, were revealed in the paper.
The association of diet quality and lifestyle factors in children and adults with ADHD: a systematic review and meta-analysis
Authors: Papanastasiou George , Drigas Athanasios , Papanastasiou Pantelis
Published: August 2021

Eating habits of individuals with learning and behavioral difficulties is an important and emerging area of ​​nutrition expertise. An unhealthy diet, combined with limited physical activity, is linked with an increased risk of chronic diseases and a lower quality of life. The study aims to review in a systematic way evidence on: (a) the relationship between diet quality and ADHD; and (b) the effect of three lifestyle factors, physical activity, quality of sleep, and stress on children and adults with ADHD. In December 2020, we searched for relevant articles in PubMed and Scopus. The studies included were those that assessed diet, physical activity, sleep, and stress, of children and adults with ADHD. We identified a total of eighteen studies with an invasive and observational approach that matched our research criteria. Fourteen of these studies were included in the meta-analysis. The pooled analysis showed that a high-diet quality decreases the prevalence of ADHD in children (OR: 0.43, 95% CI: 0.28-0.70), while a poor diet quality is associated with an increased risk of ADHD in both children and adults (OR: 2.24, 95% CI: 1.49-3.65). Also, a poor lifestyle indicates a higher prevalence of ADHD in both children and adults (OR: 1.90, 95% CI: 1.43-2.61). This study is limited to its ability to extract data from some of the included studies while sampling was limited due to the absence of studies in adults with ADHD. The present study suggests that a high-quality diet with increased consumption of fruits, vegetables, and fish, may be protective against ADHD in children. On top of that, a poor-quality diet with higher consumption of sugar, sweetened drinks, and junk food, as well as a lifestyle that is characterized by reduced sleep and physical activity can be associated with increased risk of ADHD, for both children and adults. The current domain needs more experimental data
Parâmetros genéticos de progênies interpopulacionais de milho para caracteres relacionados com tolerância à seca
Authors: Bernini Cristiani Santos , Guimarães Paula de Souza , Gallo Paulo Boller , Paterniani Maria Elisa Ayres Guidetti Zagatto
Published: August 2021

A seca é uma das maiores limitações no cultivo de plantas e um grande desafio para programas de melhoramento genético que visam obter cultivares tolerantes. Esse trabalho objetiva estimar parâmetros genéticos de 196 progênies de milho obtidas de um sintético com alto grau de tolerância cruzado com a variedade IAC Maya latente, quanto a caracteres relacionados com tolerância à seca. Os experimentos foram conduzidos na Segunda Safra de 2012, em dois locais do Estado de São Paulo, sob delineamento de látice quadrado parcialmente balanceado 14 x 14, com duas repetições. Foi possível estimar os seguintes parâmetros: variância fenotípica, variância genética entre progênies, variância aditiva, herdabilidade em sentido amplo, coeficiente de variação genética e experimental, índice e ganho de seleção. Detectaram-se progênies com alta produtividade e caracteres secundários favoráveis para seleção em Campinas e Mococa, onde houve drástica seca no florescimento. As condições de estresse hídrico em Mococa provocaram reduções na variância entre progênies para todos os caracteres, exceto para intervalo entre florescimento (IF) e número de ramificações do pendão (NRP), e no ganho estimado de seleção para florescimento masculino (FM) e feminino (FF), para NRP, massa de grãos (MG) e prolificidade (PROL).
Tradisi Intelektual Fardhu Ain dan Fardhu Kifayah Pesantren dalam Menanggulangi Terorisme
Authors: Taqiyuddin Muhammad
Published: August 2021

Most people believe that religion and ideology contribute to the spread of terrorism. Thus, it can be seen from the method of text interpretation and the implementation of over-textual and rigid interpretations in religious studies that are very instant and indoctrinal; which resulted in the spread of 'radicalism'. This aspect forgets the essence of Islamic education which emphasizes tolerance, courtesy, and love for peace. Conversely, Islamic studies that are too contextual, will eliminate the epistemological footing; that is, their identity and essence, because they merely follow all the social changes that continue to occur without regard to the wisdom and wisdom of local wisdom. Thus, the search for knowledge is no longer sacred and then encourages the loss of etiquette (loss of adab). Therefore, conceptual efforts in Islamic education need to be carried out appropriately. This qualitative model study seeks to collect fragments and data from various studies based on Islamic turots on the fardhu ‘ain and fardhu kifayah models and their relevance in various contexts of Islamic studies such as integrative aspects between religious science and social science and contemporary technology. Through content analysis, thematic analysis as well as critical discourse analysis. This study concludes that the scientific equilibrium based on fardhu ‘ain and fardhu kifayah has proven to make Islamic insights and discourse broad and flexible, so as to give birth to attitudes that both physically and spiritually represent the essence of Islamic teachings themselves.
Konsep Jihad dalam Alquran dan Aktualisasinya dalam Pendidikan
Authors: Husni Husni
Published: August 2021

This article seeks to elaborate on the meaning of jihad in the Koran and its actualization in education. This research uses the content analysis method. Through a critical study of jihad’s meaning in the Koran, this study concludes that Islamic teachings love peace among human beings and do not want hostility and violence, let alone a war. In Islam, peace is not only for Muslims themselves but for humans even though when Muslims are attacked, every Muslim is obliged to defend himself in order to realize jihad fi sabi li llah. Therefore, jihad also means keeping peace not disturbed by intruders. The actualization of jihad in education refers to three educational foundations, ontological, epistemological, and axiological foundations
Perbandingan Hukum Kewarisan Mawâni’ Irtsi dan Dzaw Al-Arham dalam Kompilasi Hukum Islam dan Undang-Undang Waris Mesir
Authors: Bisri Hasan , Muchtar Ayi Ishak Sholih
Published: August 2021

This study aims to compare the inheritance law in Egypt with the existing inheritance law in the compilation of Islamic law in Indonesia. More specifically, this comparative study focuses on the issue of mawani’ irtsi (barrier of inheritance) and inheritance of dzaw arham (relatives of male or female). This is a qualitative research based on library research. The content analysis method is used to describe mawani’ irtsi and dhaw arham in the inheritance laws of Egypt and Indonesia. The results of this study indicate differences between the inheritance laws of Egypt and Indonesia; first: the compilation of Indonesian inheritance law always adjusts to the times, while the Egyptian inheritance law is still traditional by maintaining the views of classical scholars. This is evident when it explained one barrier to inheritance namely religious differences; second: Indonesian inheritance legal material explored classical books, studied modern legislation, and observed local traditions. This can be seen when it explained that men and women get the same share as long as the basis of their agreement. While Egyptian inheritance laws do not take into account modern legislation and do not adopt local traditions; third: the material description in the compilation of inheritance law in Indonesia is concise and sometimes general in nature while the description of the material inheritance law of Egypt is more detailed. This is seen when it explained one of the barrier of inheritance is intentionally killing an heir. In the inheritance law of Egypt, it is explained in detail about types of killings which are a barrier to inheritance, while in the compilation of Indonesian inheritance law is explained in general.
Kepemimpinan Perempuan dalam Perspektif Al-Qur’an
Authors: Kamil Kamil , Suriadi Suriadi
Published: August 2021

The issue of the status of women in Islamic studies is still interesting and inexhaustible and invites polemics. Historical facts prove that women were placed in an inferior position almost throughout Muslim history while men were in a superior position. It’s happening because of the interpretation of the Qur'an carried out by classical commentators who tend to be influenced by deeply entrenched patriarchal culture. In the view of a society that adheres to patriarchy, the view of subordinating women to male superiority is influenced by religious doctrine but if you look at the doctrine of Islam itself, it turns out that the idea of egalitarianism is highly upheld. Basically, the Qur'an provides an obvious justification for the equality of women with men but at the level of reality, it turns out that egalitarian ideas in the Qur'an often clash with public responses that tend to be biased.
Memperkecil District Magnitude, Menuju Multipartai Sederhana di Dewan Perwakilan Rakyat Republik Indonesia
Authors: Muzzammil Sahel
Published: August 2021

Sejak memasuki Era Reformasi, Indonesia melalui amandemen Undang-Undang Dasar 1945 (UUD 1945) telah meneguhkan komitmen terhadap sistem pemerintahan presidensial, namun sistem kepartaian yang terbangun (multipartisme ekstrem) justru tidak kompatibel dengan sistem tersebut. Penelitian ini bertujuan memaparkan inkompatibilitas tersebut sepanjang perjalanannya hingga masa sekarang. Dengan metode penelitian doktrinal dan pendekatan sejarah di dalamnya, penelitian ini menemukan konsekuensi multipartisme ekstrem yang tidak menguntungkan bagi pemerintahan Indonesia mewujud ke dalam beberapa bentuk, mulai dari impeachment sampai dengan koalisi yang justru menyandera. Ini memberi sinyal bahwa secara subtil sesuatu perlu dilakukan untuk penyederhanaan sistem multipartai di Indonesia, termasuk dengan memperkecil apa yang dinamakan district magnitude.

 Kata kunci: Presidensialisme; Multipartai; District Magnitude.
Analisis Penghambat Perkembangan Praktek Akuntansi di Badan Usaha Milik Desa
Authors: Palupi Ade
Published: August 2021

Penelitian ini menganalisa mengapa sebuah Badan Usaha Milik Desa (BUMDes) belum mampu mempraktekkan akuntansi sesuai dengan standar akuntansi yang berlaku. Penelitian bersifat studi kasus dengan menggunakan BUMDes MW yang terletak di sebuah Desa di Jawa Barat. Data diperoleh dengan wawancara, observasi dan dokumentasi. Data dianalisa dengan pendekatan interpretatif dan menggunakan teori modal Bourdieu (1986) sebagai kerangka teori. Hasil penelitian adalah BUMDes MW belum mampu mempraktekkan akuntansi yang sesuai dengan standar akuntansi karena keterbatasan kepemilikan tiga jenis modal, yaitu modal ekonomi, modal budaya dan modal sosial. BUMDes masih menggantungkan modal keuangannya kepada pemerintah desa. Pengetahuan, ketrampilan dan sistem akuntansi yang terbatas merupakan faktor modal budaya yang belum secara optimal dimiliki oleh BUMDes. Hubungan kerjasama dengan pihak luar untuk membantu dalam pelaksanaan akuntansi juga belum dilakukan oleh BUMDes. Hal ini merupakan faktor modal sosial yang belum dimiliki oleh BUMDes. Kondisi keterbatasan ketiga modal ini juga membawa dampak manajemen keuangan BUMDes belum terlaksana dengan baik. Dengan demikian, posisi BUMDes dalam melaksanakan program pemberdayaan ekonomi desa masih belum kuat di lingkungan desa tempat BUMDes tersebut berada.

 Kata kunci: Akuntansi, BUMDes, Bourdieu, Desa
Analisis Pengaruh Islamic Governance terhadap Pengungkapan ISR pada Bank Syariah di Indonesia
Authors: Milenia Hidayah Fazrin , Syafei Ade Wirman
Published: August 2021

Penelitian ini bertujuan untuk menganalisis pengaruh Islamic governance terhadap pengungkapan Islamic social reporting pada bank syariah di Indonesia pada tahun 2016 hingga 2019. Pengukuran ISR menggunakan tingkat pengungkapan indeks ISR. Populasi dalam penelitian ini adalah bank syariah yang terdaftar di OJK. Sampel dipilih menggunakan metode purposive sampling dan memperoleh 44 sampel. Data yang digunakan adalah data sekunder, yaitu laporan tahunan. Analisis data yang digunakan adalah uji asumsi klasik, dan agresi linier berganda. Hasil dari penelitian ini menunjukkan bahwa secara simultan ukuran dewan pengawas syariah, frekuensi rapat dewan pengawas syariah, ukuran dewan komisaris, frekuensi rapat dewan komisaris, ukuran dewan direksi, dan frekuensi rapat dewan direksi memiliki pengaruh signifikan terhadap pengungkapan ISR. Berdasarkan hasil analisis secara parsial, ukuran dewan pengawas syariah, dan frekuensi rapat dewan direksi memiliki pengaruh signifikan terhadap pengungkapan ISR. Sementara itu, variabel independen lain tidak memiliki pengaruh signifinkan terhadap pengungkapan ISR.

Kata Kunci: Dewan pengawas syariah, Dewan komisaris, Dewan direksi, dan Pengungkapan ISR
Hacia un acuerdo nacional para mejorar la calidad de la educación básica y media en Colombia
Authors: De Zubiría Samper Julián
Published: August 2021

El artículo presenta una caracterización de los indicadores de calidad de la educación escolar en Colombia, relacionándolos  con algunas pruebas internacionales, mostrando las diferencias notables que existen. A si mismo se refiere a los estudios decisivos de  promoción de  dicha calidad, señalando como los docentes y la escuela se constituyen en recursos decisivos de promoción de dicha Calidad. Como consecuencia , el artículo invita a un debate responsable y serio sobre las evidencias que en ese aspecto existen en Colombia
Investigación latinoamericana sobre enseñanza eficaz
Authors: Román Marcela
Published: August 2021

La investigación Latinoamericana de enseñanza eficaz (ILEE), que se presenta en este artículo busca determinar cuales son los factores de aula asociados al desempeño de los estudiantes en América Latina y cuánto explican del rendimiento alcanzado por ellos. La ILEE analiza el desempeño en Lengua y Matemática de casi 5.000 alumnos de tercer grado de primaria y las características y prácticas pedagógicas de sus 203 docentes, distribuidos en 84 escuelas públicas de ocho países de América Latina: Bolivia, Chile, Colombia, Cuba, Ecuador,Pánama , Perú, Venezuela.Para la identificacion y cuantificación de los factores y variables utiliza un modelo multinivel de dos niveles(estudiante y aula ), desde la perspectiva analítica de valor agregado en educación. Desde dicho enfoque para identificar y conocer el aporte concreto de un factor de aula al desempeño de los estudiantes, es necesario descontar el aporte o efecto de factores y variables externas propias del estudiante y sus familias, tales como su nivel cultural y situación socioeconómica, el género, lengua materna o los años de escolarización previa a la primaria, entre otros. Los resultados y hallazgos de esta investigación permiten así conocer qué parte del desempeño de los estudiantes es responsabilidad de la escuela y qué parte es responsabilidad de las características personales y familiares de ellos o del contexto local y nacional en el cual se insertan las escuelas. Entre dichos resultados se constata el echo de que para que una escuela sea eficaz, es necesario que en ella se instalen procesos de enseñanza eficaces.
The postmethod condition, an oportunity for going into a “New pedagogical era”
Authors: Martínez Rodríguez Diana Katerine
Published: August 2021

One of the current but unknown topics for new English teachers’ generation is the Postmethod condition. Its correct use causes a great impact on the teaching and learning process,for this reason it has been considered as the starting point of a new era in respect to pedagogy specifically for some eastern countries. This is not a research article, but it is more oriented to reflect upon Kumaravadivelu’s ideasand the current situation of the Postmethod Condition in Colombia, as well as, to invite ELT teachers to become part of a “new pedagogical era”. It concludes that Postmethod is a good option to rethink about our Language Teaching practice in order to contribute to a real and authentic pedagogicalepoch.
Formar docentes en tiempos de equivalencias generalizadas
Authors: Narodowski Mariano
Published: August 2021

Este artículo analiza los cambios culturales ocurridos en la situación de la infancia y la adultez en los últimos cincuenta años y sus consecuencias en el campo de la educación escolar y, especialmente, de la formación docente. En la primera parte, y en base a los clásicos trabajos antropológicos de Margaret Mead, el artículo explica la naturaleza de la infancia y de la adultez y las condiciones culturales que daban sustento a los vínculos asimétricos que entre ellos se establecian, advirtiendo que las instituciones escolares de la modernidad funcionaban a partir de estas catacterísticas y estas condiciones. En la segunda parte de este trabajo, se desarrollan las  transformaciones operadas en el seno de la condición posmoderna de la cultura para tratar de comprender cómo las asimetrías van perdiendo su legitimidad y con ellas el posicionamiento socialmente naturalizado de la función adulta. Se explica que relaciones desjerarquizadas ocupan el lugar de las asimetrías tradicionales y que, por ende, se materializan en una generalización de los vínculos basado en posiciones crecientemente equivalentes. Finalmente, el artículo advierte respecto de las efectos de esta situación en la formación docente. Se postula la necesidad de enfoques basados en escenarios de crisis recurrentes y en la necesidad de perfiles de educadores flexibles, atentos a las oportunidades que se presentan para la construcción de asimetrías contingentes y se sugieren caminos estratégicos para ese logro.
Alternativas al desarrollo y educación en América Latina
Authors: Guido Guevara Sandra
Published: August 2021

Este artículo de reflexión presenta una propuesta alternativadesde América Latina al modelo económico del desarrollo propio de ideas capitalistas y su articulación con el campo educativo. El concepto de desarrollo y su incidencia en políticas y prácticas educativas se contrasta con perspectivasdiferentes, que tienen como principios la filosofía del “Buen Vivir” y la integración “bio-cultural”. Dentro de los proyectos educativos fundamentados en esta perspectiva se analizan dos ejemplos, el de la Universidad InterculturalAmawtay Wasi en Ecuador y el del Sistema de Educación Indígena Propio (SEIP) en Colombia.
Las búsquedas del pensamiento propio desde el buen vivir y la educación popular. Urgencias de la educación latinoamericana a propósito de las relaciones entre saber y conocimiento
Authors: Mejía J. Marco Raúl
Published: August 2021

El texto pretende organizar algunos de los ejes centrales de la  problematización que se realizó por los diferentes viceministerios  adscritos al Ministerio de Educación de Bolivia, de educación regular, alternativa  y especial, universitaria, de ciencia,  tecnología e innovación, así como con el equipo de investigación del Ministerio. En esta perspectiva, el presente documento es una especie de memoria intelectual de las diferentes reuniones, seminarios y talleres desarrollados durante esa semana en el  diálogo e interpelación con los fundamentos de la educación popular presentes en  la IEP y el proyecto educativo boliviano  consignado en la Ley 070, la cual busca  en su formulación, en el acápite de Bases, Fines y Objetivos: “la construcción del Estado plurinacional y el buen vivir”.
Los saberes tecnomediados de niños, niñas y jóvenes de hoy: entre lo online y lo offline del mundo de la vida
Authors: Ramírez Cabanzo Ana Brizet
Published: August 2021

En la actualidad se plantea que niños, niñas y jóvenes dan cuenta de la emergencia de otras formas de aprendizaje y de saber en el entorno de la tecnocultura, gracias a que configuran ecosistemas comunicativos dentro de las interacciones que mantienen con los espacios de la web 2,0; en este contexto; le corresponde a la escuela visibilizar estos saberes tecnomediados para que se haga posible comprender el carácter hipertextual, conectivo e interactivo de sus narrativas, propias de la convergencia digital, y dar cuenta de que como sujetos acontecen, más que nunca, entre lo online y lo offline.
Aprendizajes y capacidades fundamentales: claves de un nuevo escenario educativo
Authors: Ademar Horacio , Vidales Silvia Noemí
Published: August 2021

A la luz de los propósitos de democratizar  el acceso y apropiación del conocimiento,  construir ciudadanía y humanizar , en este  artículo se sostiene una perspectiva que  concibe a las capacidades asociadas a procesos tanto cognitivos como socioafectivos que garantizan la formación  integral A partir de ello, los proyectos curriculares y pedagógicos  deberán  enmarcarse   en políticas educativas inclusivas, preocupadas por la calidad, relevancia y  pertinencia de los saberes, y orientadas al  crecimiento y mejora de los sujetos y las  comunidades.
HEALTH RISK RELATED TO EXPOSURE TO TOXIC COMPOUNDS CONTAINED IN MINERAL AND SPRING WATERS
Authors: Tomczyk Katarzyna , Dziubanek Grzegorz , Kowalska Anna , Szymala Iwona , Łabuz-Roszak Beata
Published: August 2021

The aim: The study aimed to assess the content of selected toxic compounds in mineral and spring waters available on the Polish market regarding potential health risks to consumers. Materials and methods: Selected mineral and spring waters available on the Polish market were the study’s objects. The content of such chemical compounds as arsenic, cadmium, lead, copper, and mercury in selected mineral and spring waters was analyzed. The content of metals in the samples was determined by inductively coupled plasma mass spectrometry (ICP-MS). Additionally, a literature review was performed to determine nitrates contamination of bottled waters available on the Polish market. Based on the collected data, an assessment of exposure and health risk to consumers was performed. Results: Arsenic had the highest mean concentration in the analyzed water samples. Consumption of such contaminated waters may be a significant health risk factor for consumers. Literature data indicate a relatively low content of nitrates in bottled waters available on the Polish market. Consumption of such mineral waters is not a significant source of exposure and does not translate into a significant health risk for consumers. Conclusions: To ensure consumers’ health safety, there is a need to monitor the content of potentially harmful compounds in mineral and spring waters available on the Polish market.
A MATHEMATICAL MODEL FOR PREDICTING THE OUTCOME OF TREATMENT OF MULTIDRUD-RESISTANT TUBERCULOSIS
Authors: Shevchenko Olha S. , Todoriko Liliia D. , Ovcharenko Iryna A. , Pogorelova Olga O. , Semianiv Ihor O.
Published: August 2021

The aim: Predicting the effectiveness of treatment for MRI of the lungs by developing a mathematical model to predict treatment outcomes.
Materials and methods: 84 patients with MRI of the lungs: group 1 (n = 56) – with signs of effective TB treatment at the end of the intensive phase; group 2 (n = 28) – patients with signs of ineffective treatment. We used the multivariate discriminant analysis method using the statistical environment STATISTICA 13.
Results: During the discriminant analysis, the parameters of the clinical blood analysis (monocytes, stab leukocytes, erythrocytes) were selected, which were associated with high (r> 0.5) statistically significant correlations with the levels of MMP-9, TIMP-1, oxyproline and its fractions and aldosterone in the formation of the prognosis. The mathematical model allows, in the form of comparing the results of solving two linear equations and comparing their results, to predict the outcome of treatment: “1” effective treatment, “2” – ineffective treatment. Early prediction of treatment effectiveness is promising, as it allows the use of the developed mathematical model as an additional criterion for the selection of patients for whom surgical treatment is recommended, in order to increase the effectiveness of treatment.
Conclusions: An additional criterion for predicting ineffective MRI treatment, along with the criteria provided for by WHO recommendations, is a mathematical model that takes into account probably strong correlation (r = 0.5, p <0.05) between the factors of connective tissue destruction, collagen destruction, aldosterone , and indicators of a clinical blood test (between levels of OBZ and monocytes (r = 0.82, p = 0.00001), OB and monocytes (r = 0.92, p = 0.000001) OB and stab leukocytes (r = – 0.87, p = 0.0003) OBZ and stab leukocytes (r = – 0.53, p = 0.017), aldosterone and ESR.
APPLICATION OF THE SACCHAROMYCES BOULARDII PROBIOTIC COMPLEX IN THE CORRECTION OF INTRAINTESTINAL HOMEOSTASIS IN PATIENTS WITH DYSBIOTIC DISORDERS DUE TO ANTIBIOTIC THERAPY
Authors: Kvit Adrian D. , Tutka Mykhaylo M. , Laba Oksana V. , Kunovskiy Volodymyr V.
Published: August 2021

The aim: Evaluation of the effectiveness of the biotherapeutic agent Saccharomyces boulardii in the treatment complex of patients with clinical manifestations of dysbiosis and/or signs of enteric insufficiency refractory to previous therapy, to develop ways for their medical correction.
Materials and methods: The study included 209 patients, treated during 2018-2020, grouped into main and the comparison group. The main group was divided into subgroups depending on the nosological form of the underlying disease: surgical – 36, general therapeutic – 58, gynecological – 47 patients. Main group treatment was supplemented with Saccharomyces boulardii for 10-14 days from the first day of inclusion of patients in the observation group.
Results: The analysis of motor-evacuation disorders verified flatulence in 89.47%, localized epigastric pain in 22.48%, diarrhea in 55.02%, and constipation in 11.48% of cases. Based on the results of laboratory parameters, an absolute increase in the number of leukocytes in the range from 12.4 ± 1.8 x 109 / l to 14.7 ± 2.8 x 109 / l with a neutrophilic formula shift, bilirubinemia to 54.4 ± 12.2 mmol / l , elevated levels of urea to 14.7 ± 3.9 and creatinine to 0.199 ± 0.07 mmol / L.
Conclusions: After completion of the treatment course (main group), a significant (p <0.05) improvement in the general condition (decrease in stool frequency within 1–4 times (2.3 ± 0.28) per day, the absence of rumbling, flatulence and pain in abdomen) in 131 (92.9%) of 141 patients included in the study was stated. Clinical improvement was confirmed by bacteriological studies of copro-culture.
ENLIGHTENMENT ACTIVITIES IN THE FIELD OF HEALTH AND MEDICINES IN THE CONTEXT OF GOOD PHARMACY PRACTICE
Authors: Ubohov Serhii H. , Soloviov Serhii O. , Todosiichuk Tetiana S. , Todorova Violetta I. , Trokhymchuk Viktor V. , Pilipchuk Liubov B.
Published: August 2021

The aim: To study and substantiate normative, organizational and methodical approaches to the conducting of enlightenment activities in the field of health preservation and proper use of medicines in the context of the prospect of implementation of Good Pharmacy Practice (GPP) in Ukraine.
Materials and methods: The research methods are: questionnaire survey, bibliographic, systemic review, systemic analysis, generalization, graphical modeling. The questionnaire survey was conducted by filling out questionnaires by pharmacists on paper or electronic media.
Results: It is found that 51,5 % of the pharmacies surveyed are involved in sanitary enlightenment activities on health preservation and proper use of medicines. The need for introducing mechanisms to encourage pharmacy institutions to participate more actively in sanitary enlightenment among the population is substantiated. The expediency of combination of active and passive forms of sanitary enlightenment in pharmacies is shown. The enlightenment program «Health and Medicines» for the population has been developed. Methodical approaches to conducting enlightenment classes have been worked out. The algorithm infographic, describing the content of main consumer (patient) measures towards quality control of medicines purchased in the pharmacies, has been developed.
Conclusions: The implementation of the results of the study into the professional activities of pharmacists will significantly increase the erudition of citizens on preserving health and proper use of medicines and is the important element in the implementation of international GPP standard in domestic pharmacies.
YOUTH AND MENTAL HEALTH: LIFE SATISFACTION, WELLBEING, AND SOCIETAL PARTICIPATION IN THE CONTEXT OF A TRANSITIONING STATE
Authors: Vus Viktor V. , Syurina Elena V. , Brückner Tanya , Fradelos Evangelos C. , Papathanasiou Ioanna V. , Omelchenko Liudmyla M. , Vakulich Tetyana M.
Published: August 2021

The aim: Youth are important societal actors. This is especially relevant when considering countries in transition such as Ukraine. This study examines well-being and societal participation – both key signifiers of mental health – of youth in Ukraine.
Materials and methods: A descriptive, cross-sectional survey with open and closed questions was utilized (n= 1562). Participants were asked to reflect on social concerns and to evaluate their well-being in different life spheres and their own mental health through activities such as interpersonal communication, self-perception and relaxation.
Results: Students showed positive mental health through their daily activities, but mental health indicated by life satisfaction ranged according to activities, age, gender and environment. Willingness to volunteer and connection to life can be attributed to feelings of learned helplessness in the face of problems deemed too complex, and participation in volunteering was linked to positive mental health and feelings of empowerment.
Conclusions: The study contributes to understanding the status of Ukrainian youth’s mental health and the ways in which mental health is expressed. The results of the research assist in identifying avenues to reduce the impact of social frustration, improve mental health of citizens of transitional countries, and encourage social stability.
THE IMPORTANCE OF MENTAL RESILIENCE AGAINST LONELINESS DURING THE COVID-19 PANDEMIC IN DIALYSIS PATIENTS
Authors: Ołdakowska-Jedynak Urszula , Ryś Maria , Sztajerwald Tomasz , Malyszko Jolanta
Published: August 2021

The pandemic crisis of COVID-19 has caused anxiety and depressive symptoms to increase in many people worldwide. Yet, difficult situations may not only lead to various types of disorders, fears, anxieties and feelings of loss. They can also lead to positive changes, even to development or growth after experienced trauma, to positive adaptation, to changes in self-perception, changes in interpersonal relations or philosophy of life. Patients with chronic kidney disease, especially those on renal replacement therapy, often experience severe psychological problems such as anxiety disorders, depressive disorders, or difficulties related to coping with excessive stress.
The aim of our review is to disscus the appropriatness of mental health screening tools in patients with chronic kidney disease, including those on dialyses, during COVID-19 pandemic. Recently published studies indicate the limited available data evaluating the diagnostic accuracy of screening tools for mental status in patients with chronic kidney disease. This, it seems reasonable to stress the mental health associations with situational stress in this group of patients during the SARS-CoV-2 pandemic. It is also worth pointing out the need to research the impact of the mental disorders in this population on morbidity and mortality, taking into account other organ complications and the quality of life of patients not only during the SARS-CoV-2 pandemic. It is worth to to make every effort to reduce the severity of the anxiety and feelings of hopelessness in dialysis patients, to cope with the pandemic.
CLINICAL СASE: 41-YEAR MAN WITH NEUROLOGICAL SIGNS AND BACK PAIN AFTER PHYSICAL EXERCISES AND UNUSUAL IMAGING APPEARANCES
Authors: Yavorska Nataliya P. , Netliukh Andrii M. , Klymkiv Roksolana I. , Kulmatytskyi Andrii V. , Matolinets Nataliya V.
Published: August 2021

The aim was to describe the uncommon cause of back pain with successful treatment, precise diagnostic and good outcome. Lower back pain is prevalent among all the age groups and can derive from many potential anatomic sources. Here is presented the case of atypical course of back pain and neurological signs with point on importance of astute visualizations technics. This clinical case of 41-year old male patient who got back pain and neurological signs after intensive physical exercises and had no adequate response for anti-inflammatory and analgesic drugs demonstrated the importance of appropriate visualization and considering non-standard causes of these symptoms. This allowed to prescribe effective treatment with good outcome during follow-up period. This could be the supporting evidence for including such additional visualization in protocols for non-typical back pain after strenuous physical activity. Back pain is common condition with a variety of causes. It is important to consider them in case of inadequate results of treatment and use non-conventional investigation if appropriate, which improves the outcome. This could be the supporting evidence for including such additional visualization in protocols for non-typical back pain after strenuous physical activity.
Operation of a six-effect evaporator station with a deficit in the vapour balance
Authors: Lenard Piotr
Published: August 2021

During the operation of a six-effect evaporator station the vapour balance is subject of interfering incidents such as changing technological states of the process or surrounding conditions (ambient temperature e.g.) This article analyses and compares possible methods of managing the operation i.e. reaction to these incidents. In particular, methods of stabilizing the vapour balance by supplying water or thin juice to individual effects of the evaporator station and bypassing the vapours between effects are compared.
The best way of reacting to the overload of the evaporator station seems to be the bypass of vapour from an effect of higher parameters to an effect of lower parameters. This method creates a much faster reaction of the evaporator station to excessive bleeding of vapour than supply of water or thin juice, which need to mix with the juice in the vessels.
Feeding water to the thin juice tank or to one of the effects of the evaporator station to compensate excessive vapour consumption can be an acceptable solution in case of prolonged increase in vapour consumption from the evaporator station due to e.g. a significant decrease in ambient temperature.
Influence of exopolysaccharides on viscosity of sugar juices with low sucrose contents
Authors: Gruska Radosław , Antczak-Chrobot Aneta , Sobala Agnieszka , Wojtczak Maciej
Published: August 2021

The presence of dextran originating from frost-damaged or degraded beet is highly detrimental during beet sugar manufacture, because they cause difficulties in filtering the carbonatation juice. In this paper the impact of exopolysaccharides on the viscosity of low sucrose content juices including: raw juice, juice after the 1st filtration and thin juice were analyzed. Studies have shown that high molecular mass exopolysaccharides have a stronger effect on the juice viscosity than low molecular mass exopolysaccharides. However, the dynamic viscosity of technical sugar solutions (raw juice or thin juice) with exopolysaccharides at a content of up to 0.5 g/kg, is lower than the viscosity of pure sugar solutions having the same refractometric dry substance content (RDS).
Sistem Pakar dalam Menganalisis Alergi Kulit Manusia dengan Metode Certainty Factor
Authors: Adha Hafid Dwi , Sumijan S , Nurcahyo Gunadi Widi
Published: August 2021

The skin is human’s outer sense, which servers as protection from bacteria, viruses, and solar flares, and as a sense. Skin may suffer from a variety of factors, one of which is allergies. Human skin allergies result from a pressurized immune system that humans normally react to certain substances, such as food, animal hair, or medicine. In addition to the three factors, a current of society giveslittle attention to skin allergies and lack of care or awareness is a trigger factor. Thus, the aim of this research is to analyze human skin allergies using the Certainty Factor method. By conducting interviews and observations on Rahmatan Lil ‘Alamin Clinic, Padang City, found 10 skin allergic kinds, 27 skin allergic symptoms, and 50 patients data. Those data are treated using the Certainty Factor method with stages to decisive symptom and allergic code, set the rule, set the weight, and calculate Certainty Factor score. In this research, it obtained test results at a percentage of a large 92% and the most allergic diagnosed is allergic dermatitis. By the test results inferable that expert system designed can be used to determine the diagnosis of human skin allergies.
Introduction: the Interface of Culture and Communication Through Tourism
Authors: Zhang Jundan Jasmine , Doering Adam
Published: August 2021

The introduction to this special issue explores why in an "age of communication" it has become increasingly important to revisit a somewhat lost sense of communication that we describe as the interface of culture and communication. Inspired by Karen Barad's work and the diverse
range of contributions to this special issue, we reflect on the fragmented, multiplied, and diffracted sense of communication that has emerged in recent years. We examine this emergent form of communication through three interlinking yet distinct areas of study: "affective communication,"
"tourism media interface," and "interface of the human and nonhuman." Providing grounded empirical research alongside unique theoretical insights, the eight articles bring together a diverse and complex range of contexts that would otherwise not enter into conversation with one another. And
yet in their own ways each contribution challenges how communication has been approached and perceived in specific tourism settings and opens up spaces for understanding communication as diffraction and differentiation rather than a coming together. By revisiting communication in this way,
previous relationships embedded in tourism can be seen in new and interesting ways. The introduction to this special issue offers an initial exploratory conceptual framing of what we call the interface of culture and communication in effort to forefront new ways of thinking and engaging with
culture and communication in tourism studies and beyond.
Cross-cultural Communication Through Affect: The Potential for Postdisaster Tourism in Japan
Authors: Martini Annaclaudia , Vainio Anna
Published: August 2021

The success of tourism encounters can be aided by devising cross-cultural strategies so that conscious feelings (emotions) and subtle impressions (affects) of locals are communicated effectively to tourists. This article investigates how postdisaster tourism narratives, practices, and
landmarks can be used to "attune" the feelings of culturally different groups. After the Triple Disaster of 2011 in the Tōhoku region of Japan, the recovering communities have used tours as a way to support the local economy, confront their loss, and overcome trauma. As global attention
moves to new disasters, communities feel the need to attract more visitors and create new jobs for the locals. However, this has proven difficult: differences in expressing emotional responses caused tensions and dissatisfaction among locals and internationals, as locals feel misunderstood
and tourists do not see their expectations met. This hinders the tourist encounter, which is seen by some of the communities as crucial, as they feel that "being able to tell their stories" and "being remembered" is a central tenet of the recovery process. In the case of Japan, we argue, affect
can constitute an appropriate means to negotiate meaning and memory between Japanese and internationals. Affective elements are often overlooked by academics, as they are considered volatile and unstructured. There is no research that utilizes geographical and interdisciplinary theories of
affect to gain an in-depth understanding in the ways to communicate heritage and memory cross-culturally in disaster sites, as well as rigorous and appropriate approaches to affective methods. Affect can benefit both locals and visitors, as it bridges understandings of the delicate and complex
issues pertaining to disaster memory and heritage, and may lead to more socioculturally and politically sustainable approaches to planning, development, and management of tourism.
Digital Tourism Communication and Democracy
Authors: Munar Ana Maria , Ek Richard
Published: August 2021

Political philosophy is applied to analyze the democratic potential of tourism social media. This study shows that while these media have deliberative potential, they also reflect the postpolitical and postdemocratic condition in tourism digital communication. This analysis is illustrated
through the discussion of three metaphors: the menu, the stranger, and the tourist-light. The menu represents the increased invasion of lifeworlds by the commercialization and corporate regulation of the tourism social Web. The stranger symbolizes the weak accountability of online communities.
The tourist-light embodies the relevance of hedonism in virtual worlds. Social media contributes to digital narcissism and supports consumer centricity. Digital communication produces a sanitized version of tourism and entails a subtle constraint of political citizenship.