bluuebunny/crossref_metadata_2025 huggingface dataset:
KHẢO SÁT MỐI LIÊN QUAN VÀ ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ SUY SINH DỤC NAM BẰNG TESTOSTERONE THAY THẾ TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2023 - 2024
Authors: Nguyễn Trung Hiếu , Trần Huỳnh Tuấn , Lê Thanh Bình , Lê Thanh Tâm , Trần Quốc Cường
Published: December 2024

Đặt vấn đề: Suy sinh dục nam là một vấn đề sức khỏe ảnh hưởng đến nhiều nam giới. Việc chẩn đoán và điều trị sớm có thể giúp cải thiện chất lượng cuộc sống cho người bệnh. Liệu pháp thay thế testosterone, đặc biệt là testosterone gel 1%, là một phương pháp điều trị hiệu quả và được dung nạp tốt. Mục tiêu nghiên cứu: Khảo sát mối liên quan đến suy sinh dục nam và đánh giá kết quả điều trị suy sinh dục nam bằng liệu pháp testosterone thay thế. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang, tiến cứu trên 34 bệnh nhân suy sinh dục nam được chỉ định điều trị liệu pháp testosterone thay thế tại Bệnh viện Trường Đại học Y Dược Cần Thơ từ tháng 12/2023 đến hết tháng 06/2024. Tiến hành theo dõi 3 tháng điều trị. Kết quả: Nồng độ testosterone có mối liên quan đến các yếu tố: chỉ số khối cơ thể, đái tháo đường, vòng bụng, rối loạn lipid máu, giãn tĩnh mạch thừng tinh (p < 0,05). 100% bệnh nhân có tăng nồng độ testosterone trong máu sau 3 tháng điều trị, có sự cải thiện triệu chứng suy sinh dục sau điều trị bằng bộ câu hỏi triệu chứng thiếu hụt nội tiết tố nam và bộ câu hỏi chỉ số quốc tế về chức năng cương dương. 5,88% ghi nhận tác dụng phụ khi dùng testosterone gel. Kết luận: Liệu pháp thay thế testosterone được coi là liệu pháp tiêu chuẩn cho suy sinh dục nam, trong đó testosterone gel 1% là biện pháp đơn giản và được dung nạp tốt.
ĐÁNH GIÁ TÁC DỤNG CHỐNG OXY HÓA IN VITRO CỦA CAO CHUẨN HÓA QUẢ THỂ NẤM VÂN CHI ĐỎ (PYCNOPORUS SANGUINEUS MH225776)
Authors: Đặng Bảo Trân , Nguyễn Thị Ngọc Vân , Đặng Duy Khánh , Dương Tuyết Ngân , Đặng Thị Tú Mai , Phạm Thanh Toàn , Lý Ngọc Yến Linh , Cao Yến Linh , Trần Đức Tường , Dương Xuân Chữ
Published: December 2024

Đặt vấn đề: Nấm Vân chi đỏ là một loại nấm dược liệu giàu các hoạt chất có hoạt tính sinh học, trong đó đáng quan tâm là hợp chất phenolic. Phenolic hiện diện ở nhiều loài thực vật khác nhau và được chứng minh là có khả năng chống oxy hóa vô cùng hiệu quả. Tuy nhiên, chưa có nghiên cứu nào chứng minh khả năng chống oxy hóa của phenolic có trong cao chuẩn hóa quả thể nấm Vân chi đỏ. Mục tiêu nghiên cứu: Xác định hàm lượng phenolic và đánh giá tác dụng chống oxy hóa in vitro của cao chuẩn hóa quả thể nấm Vân chi đỏ được trồng tại Trường Đại học Đồng Tháp. Đối tượng và phương pháp nghiên cứu: Cao chuẩn hóa quả thể nấm Vân chi đỏ; định lượng phenolic bằng phương pháp HPLC với đầu dò PDA; đánh giá tác dụng chống oxy hóa in vitro của cao chuẩn hóa quả thể nấm Vân chi đỏ bằng ba phương pháp DPPH, ABTS•+ và RP. Kết quả: Hàm lượng phenolic là 7,33mg/100g cao; cao chuẩn hóa quả thể nấm Vân chi đỏ thể hiện hoạt tính chống oxy hóa tốt khi khảo sát ở cả ba phương pháp DPPH, ABTS•+ và RP, với giá trị IC50  lần lượt là 73,84 µg/mL ± 3,24; 73,76 µg/mL ± 2,25 và 85,18 µg/mL ± 2,29. Kết luận: Dựa vào giá trị IC50 ở cả 3 phương pháp DPPH,  ABTS•+ và RP nhận thấy cao chuẩn hóa quả thể nấm Vân chi đỏ có hoạt tính chống oxy hóa in vitro.
ÇALIŞMA BELLEĞİ VE KARAR VERME İLİŞKİSİNİN NÖROPSİKOLOJİK TEMELLERİ
Authors: Coşkun Nilgün
Published: December 2024

Bu çalışmanın amacı insanların günlük yaşamlarında büyük önem taşıyan bilişsel beceriler arasında bulunan çalışma belleği ve karar verme becerileri arasındaki ilişkiyi nöropsikolojik temelleri açısından inceleyen çalışmaların derlenmesidir. Literatür incelendiğinde, karar verme fonksiyonlarının frontal korteksin ventromedial alanı ile ilişkili olduğuna bunun yanında çalışma belleğinin dorsolateral alan ile ilişkili olduğuna dair kanıtlar görülmektedir. Bu durum iki işlev arasında bir ayrışma olduğuna işaret olarak kabul edilebilir. Bununla birlikte, çalışma belleği ile ilişkili olduğu düşünülen dorsolateral prefrontal korteks bölgesinde bozulma yaşayan bireylerin çalışma belleği performanslarının düştüğü ancak bulguların aynı zamanda karar verme performanslarının da etkilendiğini göstermesi alanlar arasındaki etkileşimi kanıtlamaktadır.
International Drug Repurposing Patent Landscaping, Part 2: The Early Months of Covid-19
Authors: Mucke Hermann
Published: December 2024

This study presents and discusses international patent applications claiming known pharmaceutical agents for repurposed use in the treatment of Coronavirus Disease 2019 (Covid-19). These applications were published by the World Intellectual Property Office (WIPO) during the second half of 2021, corresponding to filings made during the first six months of the pandemic (January to June 2020). Of the 93 identified documents, 46 claimed agents that had been approved, were in development, or had been discontinued as antiparasitics, antibiotics, anticancer agents, or immunomodulators. The remaining 47 documents concerned a wide variety of other original uses, from psychiatry to osteoporosis, and correspondingly diverse mechanisms of action. The most significant patent applications are presented and discussed in brief. The landscape of patent applications seeking to repurpose pharmaceutical agents for use in the treatment of Covid-19, filed during the early stages of the pandemic, is impressive. It provides insight into the intellectual property track pursued by industry, academia, and government organizations during these tumultuous months.
İlkokul Öğrencilerinin Eleştirel Düşünme Eğilimlerinin Çeşitli Değişkenler Açısından İncelenmesi
Authors: Oğuz Osman , Aybek Birsel
Published: December 2024

Bu araştırmanın amacı; ilkokul öğrencilerinin eleştirel düşünme eğilimleri ile çeşitli değişkenler arasındaki ilişkileri belirlemektir. Araştırma ilişkisel tarama modelinde bir çalışmadır. Bu araştırmanın örneklemi 2023-2024 eğitim öğretim yılında Adana’nın Karataş ilçe merkezinde bulunan ilkokullarda öğrenim gören 3 ve 4. sınıf öğrencilerinden oluşan 283 öğrenci oluşturmaktadır. Araştırmada veriler, eleştirel düşünme eğilimi için Akar ve Uluçınar (2021) tarafından geliştirilen “İlkokul Öğrencileri için Eleştirel Düşünme Eğilimleri Ölçeği” kullanılarak toplanmıştır. Öğrencilerin sosyo-demografik özelliklerini belirlemek için ise araştırmacılar tarafından geliştirilen Kişisel Bilgi Formu’ndan yararlanılmıştır. Verilerin analizinde betimsel istatistiklerin yanı sıra, t testi analizi, Pearson momentler çarpımı katsayısı korelasyonu, tek yönlü varyans (ANOVA) ve çoklu doğrusal regresyon analizi yöntemleri kullanılmıştır. Araştırmanın sonucunda öğrencilerin eleştirel düşünme eğilimi puanlarının iyi olduğu, eleştirel düşünme eğilimi puanlarının; cinsiyet değişkeninde anlamlı bir farklılık oluşturmadığı ancak akademik başarı, anne-baba eğitim düzeyi, kitap okuma sıklığı, ailenin gelir düzeyi ve öğrencilerin katıldıkları sosyal aktivite değişkenlerine göre anlamlı farklılıklar olduğu sonucuna ulaşılmıştır. Ayrıca öğrencilerin eleştirel düşünme eğilimi üzerinde akademik başarı, kitap okuma sıklığı ve baba eğitim durumunun anlamlı bir yordayıcı olduğu sonucuna ulaşılmıştır.
The role of state institution «Republican research center for radiation medicine and human ecology» in the healthcare system and its development prospects
Authors: Rozhko A. V. , Zyblevа S. V. , Zharikova A. V. , Mitsura V. M. , Baginskaya N. N.
Published: December 2024

The article highlights the main results of the activities of the state institution «Republican Research Center for Radiation Medicine and Human Ecology» in research and diagnostic and treatment work. The role of the institution in the development of the healthcare system of the Gomel region has been shown, achievements in improving the health of the population affected by the Chernobyl accident, research and educational activities has been reflected. Promising areas of activity has been identified
Development of Digital Registration Information System in Kelurahan to Improve Administration Efficiency and Transparency
Authors: Putri Riski Ananda
Published: December 2024

This research aims to develop a digital registration information system in urban villages to increase efficiency and transparency in administrative processes. This web-based designed information system is expected to be able to overcome various problems that often occur in manual administration, such as data inaccuracies, long processing times, and lack of transparency. The research methods used include literature study, needs analysis, system design, implementation, and evaluation. At the initial stage, a needs analysis is carried out to identify the features needed by users, namely village staff and residents.The results of this analysis are used as a basis in designing system architecture and user interfaces. System implementation is done using the latest web technology that ensures the system can be accessed easily and securely. Next, the system is tested through several stages of trials involving end users to ensure its functionality and reliability.The results showed that this digital registration information system was able to increase the efficiency of the administrative processby up to 40% compared to the manual method, as well as increase transparency through real-time application status tracking features and structured data storage. With this system, residents can register and monitor the status of their applications online, reducing the need to come directly to the village office. The conclusion of this study is that the development of a digital registration information system in urban villages can significantly improve administrative efficiency and transparency, as well as provide convenience for residents in accessing public services. It is expected that this system can be widely implemented in various urban villages to support the modernization of public services in Indonesia.
Nghiên cứu mô hình thực nghiệm xe máy điện hai bánh trong vận tải hành khách đô thị
Authors: Đinh Quang Toàn  , Đào Phúc Lâm  , Bùi Đăng Trình
Published: December 2024

Nghiên cứu này nhằm phân tích các yếu tố ảnh hưởng đến chi phí khai thác và vận hành xe điện 2 bánh trong vận tải hành khách tại các đô thị. Trong bối cảnh đô thị hóa và gia tăng ô nhiễm môi trường, việc áp dụng xe điện 2 bánh trở thành một giải pháp quan trọng nhằm giảm thiểu khí thải và ùn tắc giao thông. Nghiên cứu đã xác định các yếu tố chính ảnh hưởng đến chi phí này, bao gồm chi phí năng lượng, chi phí bảo trì, chi phí bảo hiểm và chi phí quản lý. Sử dụng mô hình hồi quy để phân tích dữ liệu thu thập từ 35 xe điện PCX Honda, kết quả cho thấy mức tiêu hao năng lượng, sửa chữa và bảo trì là những yếu tố chính có tác động đáng kể đến chi phí vận hành. Kết quả cũng chỉ ra rằng cần có chính sách hỗ trợ từ chính phủ để thúc đẩy việc sử dụng xe điện 2 bánh, tạo điều kiện cho phát triển một hệ thống giao thông bền vững và thân thiện với môi trường. Nghiên cứu không chỉ có ý nghĩa thực tiễn mà còn cung cấp cái nhìn khoa học để định hướng phát triển giao thông trong tương lai.
Türkiye’de okul öncesi dönemde “okuryazarlık” kavramı ile ilgili yapılan lisansüstü tezler
Authors: Serdaroğlu Hasan Uğur , Bekır Hatice
Published: December 2024

Okul öncesi eğitimin temel amaçlarından biri çocukları ilkokula hazırlamaktır. Bu amaca ulaşmak için doğumdan itibaren gelişmeye başlayan okuryazarlık sürecini inceleyen araştırmalar okul öncesi dönemi ele alacak şekilde yapılmış, erken okuryazarlığa odaklanılmıştır. Zaman içerisinde okuma ve yazmanın çok daha fazlası olan afet okuryazarlığı, fiziksel okuryazarlık, ekolojik okuryazarlık, sürdürülebilirlik okuryazarlığı, kültürel okuryazarlık, matematik okuryazarlığı, müze okuryazarlığı gibi birçok yeni okuryazarlık türü karşımıza çıkmaktadır. Bundan yola çıkarak bu çalışmada gün geçtikçe artan ve kavramsallaşan okuryazarlık türlerinin okul öncesi dönemde nasıl ele alındığı, nelere odaklanıldığını belirlemek amaçlanmıştır. Bu amaç doğrultusunda okul öncesi dönemde okuryazarlık kavramı ile ilgili yayımlanan lisansüstü tezler, içerik analizi yöntemlerinden betimsel içerik analizi yaklaşımıyla incelenmiştir. Araştırma sonucunda, okul öncesi dönemde okuryazarlıkla ilgili yayımlanan lisansüstü tezlerin sayısının arttığına, çoğunlukla nicel yöntemlerle gerçekleştirildiğine ve en fazla yüksek lisans tezi olarak yayımlandığına ulaşılmıştır. İncelenen araştırmaların çalışma grubunun çoğunlukla sadece çocuk, ebeveyn ve öğretmen olacak şekilde tek bir gruptan oluştuğu; babalara çok az yer verildiği, büyük ebeveynlere neredeyse yer verilmediği saptanmıştır. Okul öncesi dönemde okuryazarlıkla ilgili lisansüstü tezlerin neredeyse yarısı erken okuryazarlık kapsamında yayımlanmıştır. İncelenen çalışmalarda, düşük oranda araştırma yapılan okuryazarlık türleri arasında ev okuryazarlığı, dijital okuryazarlık, medya okuryazarlığı, bilimsel okuryazarlık, duygusal okuryazarlık, çevre okuryazarlığı, sağlık okuryazarlığı, iklim okuryazarlığı, müzik okuryazarlığı, beslenme okuryazarlığı, teknolojik okuryazarlık, finansal okuryazarlık, görsel okuryazarlık, veri okuryazarlığı, harita okuryazarlığı, bilgi okuryazarlığı, su okuryazarlığı, reklam okuryazarlığı, eleştirel okuryazarlık ve değerlendirme okuryazarlığı bulunmaktadır. Türkiye’de okuryazarlık araştırmaları yapılmasına ihtiyaç olduğu ve bu ihtiyacın karşılanmasında özellikle okul öncesi dönemle ilgili yapılacak okuryazarlık araştırmalarının katkı sağlayacağı düşünülmektedir. Bulgular alanyazın ve okul öncesi eğitim programı doğrultusunda değerlendirilerek önerilere yer verilmiştir.
Mitybos terapinė reikšmė onkologinių pacientų sveikatai
Authors: Misevičienė Jūratė , Rakauskienė Vitalija
Published: December 2024

Kiekvienais metais pasaulyje nuo onkologinių ligų miršta apie aštuonis milijonus žmonių. Pagrindinės priežastys vėžio ligos kontekste – nepakankamas maisto suvartojimas, sumažėjęs fizinis aktyvumas ir katabolinių medžiagų apykaitos sutrikimai. Klinikinis požiūris į sergančius onkologinėmis ligomis per pastarąjį dešimtmetį labai pasikeitė: pereinama prie labiau į asmenį orientuoto terapinio plano, pacientų įgalinimo ir įtraukimo į visus galimus priežiūros aspektus. Daugiamodalės intervencijos, įskaitant farmakologines priemones, mitybos paramą ir fizinius pratimus, gali būti pagrįstas būdas užkirsti kelią vėžio kacheksijai, sarkopenijai, nes dažnas vėžiu sergančių pacientų mitybos trūkumas gali apriboti atsaką net į geriausius gydymo būdus, jei mitybos problemos nėra tinkamai valdomos. Teorine ir praktine reikšme svarbu vertinti onkologine liga sergančiųjų mitybos terapinę naudą organizmui priešvėžinio gydymo ir ligos remisijos laikotarpiu. Naujų tikslinių terapijų ar imunomoduliatorių įvedimas susijęs su ilgesniu asmenų išgyvenamumu. Šiame besikeičiančiame kontekste tiksli ir savalaikė mityba aktyvaus gydymo metu išlieka labai svarbi. Žmonėms, sergantiems vėžiu, yra didelė ligos pasikartojimo ir gretutinių ligų rizika, todėl reikia strategijų šiai rizikai sumažinti. Viena perspektyvi strategija, skirta keičiamiems gyvenimo būdo veiksniams, įskaitant mitybą ir fizinį aktyvumą. Tačiau šiuo metu trūksta veiksmingų, įrodymais pagrįstų išteklių perimti naujus gyvenimo būdo įpročius. Taikyti tyrimo metodai: mokslinės literatūros analizė; kiekybinis tyrimas – anketinė apklausa; tyrimo duomenų aprašomoji ir grafinė analizė. Atlikus tyrimą ir įvertinus mitybos terapinę reikšmę sveikatai, nustatyta, kad vartojant maistines medžiagas, mikroelementus, makroelementus daugumai respondentų sveikata pagerėjo visame vėžio kontinuume. Nepakankama mityba turi būti įtraukta į paciento diagnozę, o mitybos intervencijos turi būti laikomos pagrindine paciento medicininės terapijos dalimi.
Šlaunies tiesiojo raumens viskoelastinių savybių bei KMI sąsajos po kelio sąnario endoprotezavimo
Authors: Lenčiauskienė Daiva
Published: December 2024

Daugiau kaip 50 proc. pacientų, kuriems atliekamas kelio sąnario endoprotezavimas, yra nutukę (Odum ir kt., 2013). Be lokalaus uždegimo, sukelto šlaunies tiesiamojo raumens pažeidos operacijos metu, organizmą veikia lėtinis, sisteminis, nutukimo paveiktas uždegimas. Blogėja sisteminė kraujotaka, mažėja raumeninio audinio jėga ir storis, didėja intraraumeninių riebalų kiekis, vystosi atsparumas insulinui (Vincent ir kt., 2012). Palangos reabilitacijos ligoninėje atliktas kiekybinis, vienmomentinis skerspjūvio tyrimas. Duomenys buvo renkami nuo 2020-06-30 iki 2020-09-30. Tyrime dalyvavo 21 (68,2 ± 4,61 metų) pacientas po kelio sąnario endoprotezavimo operacijos. Atsižvelgiant į KMI (kūno masės indeksą), tiriamieji suskirstyti į tris grupes. I grupės tiriamieji turėjo antsvorį, II grupės – I laipsnio nutukimą, III grupės – II laipsnio nutukimą. Kiekvienoje grupėje buvo po 7 tiriamuosius. Šio tyrimo tikslas – įvertinti šlaunies tiesiojo raumens viskoelastinių savybių bei KMI sąsajas po kelio sąnario endoprotezavimo. Tyrimo metu taikyti šie tyrimo metodai: KMI skaičiuoklė ir miotonometrija. Rankiniu MYOTON-PRO miotonometru vertintas šlaunies tiesiojo raumens tonusas (raumens osciliacijos dažnis), elastingumas (raumens gęstančių virpesių logaritminis dekrementas) ir kietumas. Statistinė duomenų analizė atlikta naudojant SPSS 25,0 statistinės analizės paketus. Ryšiui tarp parametrų įvertinti naudotas neparametrinis Spirmeno koreliacijos koeficentas r, įvertintas jo patikimumas. Esant p < 0,05 koreliacijos koeficientas vertintas kaip statistiškai reikšmingas. Tyrimo rezultatai atskleidė labai stiprų atvirkštinį antsvorio ryšį su tiesiojo šlaunies raumens tonusu (r = -0,82 p < 0,05) ir elastingumu (r = -0,75 p = 0,05) bei I laipsnio nutukimo ryšį su tiesiojo šlaunies raumens kietumu (r = -0,75 p = 0,05). Visų grupių tiriamųjų šlaunies tiesiojo raumens viskoelastinių savybių sąsajų su KMI rezultatai parodė stiprų atvirkštinį KMI ryšį su tiesiojo šlaunies raumens kietumu (r = -0,79 p < 0,01), tonusu (r = -0,66 p < 0,01) ir vidutinio stiprumo ryšį su šlaunies tiesiojo raumens elastingumu (r = -0,50 p < 0,05). Esant II laipsnio nutukimui tiesiojo šlaunies raumens viskoelastinės savybės buvo blogesnės nei esant antsvoriui ar I laipsnio nutukimui.
Lietuvos kolegijų socialinės atsakomybės ataskaitų palyginamasis vertinimas
Authors: Nastaravičė Karolina , Kazlauskienė Vilma , Klimavičienė Irena
Published: December 2024

Socialinės atsakomybės tema tampa vis svarbesnė ne tik privačiam, bet ir viešajam sektoriui. Visi šioje srityje įgyvendinti pokyčiai ir atlikta pažanga dažniausiai atsispindi socialinės atsakomybės ataskaitose. Tačiau kyla daug diskusijų dėl pačių socialinės atsakomybės ataskaitų rengimo, kadangi dauguma gairių, rekomendacijų, standartų ar kt. turi tam tikrų spragų. Pasigendama detalesnio reikalavimų, keliamų socialinės atsakomybės ataskaitų turiniui, apimčiai pristatymo. Be to, stokojama mokslinių publikacijų, kuriuose būtų nagrinėjami aukštųjų mokyklų socialinės atsakomybės ataskaitų rengimo ir pateikimo klausimai. Šiame straipsnyje, taikant mokslinės literatūros analizės ir aukštųjų mokyklų socialinės atsakomybės bei kitų dokumentų analizės metodus, siekiama įvertinti Lietuvos kolegijų socialinės atsakomybės ataskaitas. Atlikta mokslinės literatūros ir aukštųjų mokyklų socialinės atsakomybės ataskaitų bei kitų dokumentų analizė parodė, kad yra parengti įvairūs standartai, gairės, klausimynai, nurodantys koks turėtų būti socialinės atsakomybės ataskaitų turinys. Vieni iš pagrindinių, kurie aptariami straipsnyje, tai Pasaulinės atskaitingumo iniciatyvos standartai, ISO 26000 standarto gairės ir Jungtinių Tautų Pasaulinio susitarimo klausimynas. Panevėžio kolegija, Šiaulių valstybinė kolegija, Kauno kolegija ir Vilniaus kolegija taip pat rengia bei teikia socialinės atsakomybės ataskaitas, vadovaujantis įvardintais dokumentais, kadangi priklauso Jungtinių Tautų pasaulinio susitarimo iniciatyvai bei yra įpareigotos teikti socialinės atsakomybės ataskaitas. Pastebėta, kad visos kolegijos rengia ir teikia skirtingas socialinės atsakomybės ataskaitas – skiriasi struktūra, apimtis, pavadinimas ir kt. Pastebima, kad tiek Pasaulinės atskaitingumo iniciatyvos standartai, tiek ISO 26000 standarto gairės, tiek Jungtinių Tautų Pasaulinio susitarimo klausimynas palengvina socialinės atsakomybės ataskaitų rengimą ir pateikimą aukštosiose mokyklose, tačiau šių dokumentų išsamumo, aiškumo, tinkamumo klausimas išlieka tolimesnių tyrimų šioje srityje objektu.
Bendrojo polifenolinių junginių kiekio ir antioksidacinio aktyvumo nustatymas fermentuotuose siauralapio gauromečio (Chamerion angustifolium L.) lapuose
Authors: Čerčikienė Irena , Jurkevičiūtė Jolanta , Radveikienė Ingrida
Published: December 2024

Polifenoliniams junginiams, esantiems augaluose, kaip ir kitoms biologiškai aktyvioms medžiagoms, šiuo metu skiriamas didelis dėmesys dėl jų antioksidacinių, antimikrobinių ir kt. savybių. Literatūroje nurodoma, kad augalinės kilmės žaliavose bei maisto produktuose esantys antioksidantai gali sumažinti laisvųjų radikalų kiekį organizme arba stabdyti jų susidarymą, taip pat jie gali padėti išvengti širdies ir kraujagyslių ligų, uždegiminių ir neurodegenericinių sutrikimų, vėžinių ląstelių dauginimosi ir kt. Siauralapio gauromečio (Chamerion angustifolium L.) lapai nuo seno naudojami tradicinėje ir liaudies medicinoje, jiems būdingas priešuždegiminis, antioksidacinis, priešvėžinis, skausmą mažinantis poveikis. Ieškant naujų skonių ir siekiant išsaugoti organoleptinės arbatų savybės bei vaistinėse žolelėse esančias biologiškai aktyvias medžiagas vis plačiau naudojamas jų fermentavimas, todėl svarbu parinkti tinkamą fermentacijos trukmę. Šiuo tyrimu buvo siekiama nustatyti kietafazės fermentacijos įtaką polifenolinių junginių kiekiui ir antioksidaciniam aktyvumui siauralapio gauromečio lapuose. Bendras polifenolinių junginių kiekis siauralapio gauromečio lapų ekstraktuose nustatytas Folin-Ciocalteu spektrofotometrijos metodu, o antioksidacinis aktyvumas nustatytas 2,2-difenil-1-pikrilhidrazilo (DPPH·) radikalų surišimo metodu. Tyrimu nustatyta, kad bendras polifenolinių junginių kiekis ir antioksidacinis aktyvumas fermentuoto siauralapio gauromečio lapuose priklauso nuo kietafazės fermentacijos trukmės. Optimali siauralapio gauromečio kietafazės fermentacijos trukmė yra 36 val., šiomis sąlygomis nustatytas didžiausias polifenolinių junginių kiekis (1,816 ± 0,005 mg/g) ir antioksidacinis aktyvumas (41,7 ± 1,51 proc.). Ilginant kietafazės fermentacijos trukmę bendras polifenolinių junginių kiekis ir antioksidacinis aktyvumas mažėjo. Įvertinus antioksidacinio aktyvumo priklausomybę nuo bendrojo polifenolinių junginio kiekio, nustatyta koreliacija tarp šių rodiklių (Rb = 0,782). Galima teigti, kad kuo daugiau polifenolinių junginių yra fermentuoto siauralapio gauromečio lapuose, tuo didesniu antioksidaciniu aktyvumu jis pasižymi.
Garbage in/Garbage out
Authors: Oluoch Isaac , Gerritsen Isabel , Wanjiru Nicera , Rovoga Eric
Published: December 2024

Geographic information has become increasingly relied upon in supporting decision-making in public administration as well as humanitarian intervention. One domain where such information has been important is waste management, notably improving the mapping of areas with the highest waste accumulation, finding suitable locations for landfills as well as planning transport routes for collection services. The utility of geographic information here reflects the capacity of visual information to mediate between human actors (e.g. municipal authorities) and the world in which they wish to make changes . In this paper, we shall be presenting insights from five focus groups that were conducted to assess the impact of the visualisation of waste accumulation in the ‘slums’ and informal settlements in Nairobi, Kenya, along with  factors that affected the readability and understanding of the visualisations presented in the focus groups. In this paper, we will be considering: i) the impact of design elements (e.g. level of detail and symbology) on raising problem awareness of the participants regarding the waste accumulation; and ii) the ethical and political concerns that arise from the way communities living in the DUAs are perceived from the visualisations.
Algunos fundamentos de decisiones educativas e investigativas en didáctica de las ciencias: un aporte a la reflexión de los docentes de biología
Authors: Peme-Aranega. C.
Published: December 2024

Abstract
The article deals with the thrcc standing paradigma in Social Sciences, which are the basis br educationalresearch: the pusitivist paradigm, the symbolic-interpretative, and the critical. It makes an anlysis of thefundamental principies of each one: the theoretical supports received; the purposes, the niethodologies. thetechniques and (lic instrumenis; the norms and the rules of research; the assumptions about knowledge; andthe considerations about the relationship between the scienlific knowledge and the social practice -that aretransferred, in the area of Education, in interactions between the Lheory and the educational practice, andbetween the researcher (scientific) and the practitioner (teacher). Tite purpose of the article it ro presentsume analysis' elements tu allow the Science Teaching researchers (in front of the simultaneous existenceof the three paradigms) tu think about diiferent altematives of work and tu adopt consclouS and foundedpostures for their actions. The article remarks that the future researches need not only a solid fonustion, butalso a perrnanent research practice.
Development of Sharia-Based Ecotourism in Pagar Alam City (Potential and Strategy in Utilizing Natural Resources Sustainably)
Authors: Alamsyah Syahril Ramadhon
Published: December 2024

Sharia integration in ecotourism means combining the basic principles of ecotourism such as nature conservation and local community empowerment with sharia rules. The development of ecotourism in Pagar Alam is a strategic opportunity, not only to increase the income of local communities, but also to support environmental conservation efforts and cultural heritage. In addition, with the increasing interest in sharia-based tourism, Pagar Alam has a great opportunity to attract Muslim tourists through the development of ecotourism destinations that are in accordance with Islamic principles.
Corporate Debt Structure over the Global Credit Cycle
Authors: Boyarchenko Nina , Elias Leonardo
Published: December 2024

We study the determinants of active debt management through issuance and refinancing decisions for firms around the world. We leverage instrument-level data to create a comprehensive picture of the maturity, currency, and security type composition of firms' debt for a large cross-section of countries. At the instrument level, we estimate a predictive model of prepayment as a function of interest costs savings and maturity lengthening motives. We document that there is substantial heterogeneity in prepayment across bonds and loans and across firms, depending on their reliance on bank lending. While debt prepayment is generally successful at extending average maturities and lowering interest rate costs at the firm level, these benefits appear smaller for issuers in emerging market economies. Tight global credit conditions reduce both the ability to prepay debt early and the effectiveness of debt refinancing in reducing interest costs and rollover risk. Put together, our results show that the impact of global credit conditions on firms' debt structure can be traced back to how instrument-level prepayment incentives change over the global credit cycle.
Penggunaan Metode Ilhaq Dalam Menentukan Status Hukum Pewarna Karmin Pada Industri Makanan dan Minuman
Authors: H. A. Sukandar  , Sudarna Nanong , Faridatul Anwar Dalfa , Hidarya Ia
Published: December 2024

Penelitian ini bertujuan untuk mengeksplorasi penerapan metode Ilhaq dalam menetapkan status hukum halal atau haram pewarna karmin dalam industri makanan dan minuman di Indonesia. Dengan populasi Muslim yang besar, permintaan akan kejelasan status halal untuk bahan seperti karmin semakin meningkat, terutama karena sumbernya berasal dari serangga. Hasil penelitian menunjukkan perbedaan interpretasi antara Nahdlatul Ulama (NU) di Jawa Timur dan Majelis Ulama Indonesia (MUI) terkait status halal karmin. NU cenderung menganggap karmin tidak halal, sementara MUI memberikan pandangan lebih fleksibel dengan mempertimbangkan proses pengolahan. Oleh karena itu, penelitian ini menyarankan perlunya kajian lebih mendalam untuk menghasilkan fatwa yang lebih konsisten dan memberikan kepastian hukum bagi konsumen dan produsen. Dengan pemahaman yang lebih jelas tentang metode Ilhaq dan prinsip-prinsip hukum Islam, diharapkan lembaga-lembaga terkait dapat merumuskan panduan komprehensif mengenai status halal karmin. Hal ini akan membantu konsumen dalam memilih produk sesuai keyakinan mereka dan memastikan produsen patuh terhadap standar halal yang diakui.
Manuela Álvarez Jurado. La visibilidad del traductor en los tratados de agricultura, agronomía, viticultura y vinificación (1773-1900).
Authors: Gómez Campos Manuel
Published: December 2024

Reseña
Genre et sexualité dans la littérature polynésienne
Authors: Vela Ameneiro Natalia
Published: December 2024

El género y la sexualidad siguen siendo temas tabú en muchas sociedades. La literatura puede convertirse en un medio para comprender que las identidades de género y las sexualidades son mucho más variadas de lo que pensamos. En la Polinesia Francesa, el māhū -o tercer género- y el raerae -o trans- son dos identidades visibilizadas en la literatura aut´óctona, como se ve en las obras de Chantal Spitz y Titaua Peu.

Le genre et la sexualité restent des sujets tabous dans de nombreuses sociétés. La littérature peut devenir un moyen de comprendre que les identités de genre et les sexualités sont beaucoup plus variées qu'on ne le pense. En Polynésie française, le māhū - ou troisième genre - et le raerae - ou trans - sont deux identités rendues visibles dans la littérature indigène, comme en témoignent les œuvres de Chantal Spitz et de Titaua Peu.
Transformasi Digital dalam Manajemen Jasa: Tantangan dan Peluang di Era Industri 4.0
Authors: Wahyuningjati Tri , Iskandar Syafna Hanifa , Sabrina Afiifah Nur , Saleh Mohamad Zein
Published: December 2024

Digital transformation in service management is becoming an important necessity in the Industry 4.0 era, which is characterized by technological advances such as the Internet of Things (IoT), artificial intelligence (AI), and big data. This research explores the challenges and opportunities facing the services sector in adopting digitalization. Digital transformation offers benefits such as improved operational efficiency, personalization of services, and better data-driven decision-making. However, challenges such as digital competency gaps, organizational culture resistance, cybersecurity, and technology infrastructure limitations are also identified. Through a qualitative approach, this research presents an in-depth analysis covering technology integration strategies, organizational culture change, and digital collaboration to improve customer experience. The results provide important insights for service companies in optimizing digitalization strategies to improve competitiveness and relevance in the market.
Abstrak
Transformasi digital dalam manajemen jasa menjadi kebutuhan penting di era Industri 4.0, yang ditandai oleh kemajuan teknologi seperti Internet of Things (IoT), kecerdasan buatan (AI), dan big data. Penelitian ini mengeksplorasi tantangan dan peluang yang dihadapi sektor jasa dalam mengadopsi digitalisasi. Transformasi digital menawarkan manfaat seperti peningkatan efisiensi operasional, personalisasi layanan, dan pengambilan keputusan berbasis data yang lebih baik. Namun, tantangan seperti kesenjangan kompetensi digital, resistensi budaya organisasi, keamanan siber, dan keterbatasan infrastruktur teknologi juga diidentifikasi. Melalui pendekatan kualitatif, penelitian ini menyajikan analisis mendalam yang mencakup strategi pengintegrasian teknologi, perubahan budaya organisasi, serta kolaborasi digital untuk meningkatkan pengalaman pelanggan. Hasil penelitian memberikan wawasan penting bagi perusahaan jasa dalam mengoptimalkan strategi digitalisasi untuk meningkatkan daya saing dan relevansi di pasar.
Kata kunci: transformasi digital, manajemen jasa, Industri 4.0, tantangan, peluang.
Museums and Community; Bridging the Gap between the Museum and its Audiences through Research & Education
Authors: Thebele Winani
Published: December 2024

The above theme chosen by the Romanian Journal of Museums, together with the theme for International Museums Day for 2024 (Museums, Education and Research) are clearly embedded in the ICOM definition for museums, which emphasises the educational role of the museum and its dynamic relationship with society. Museums offer a captivating preview into our collective heritage, making them indispensable places for learning, inspiration, and wonder. This also talks about a museum whose doors are open to all sectors of the society. It serves society through “community education”, entertainment and as a platform for discussions, performances, showcasing talents and celebrating culture. It covers different activities that allow individuals and the community to make positive changes in their own lives, through education, personal development, self-awareness and pride. The museum, therefore, becomes a community centre with a participatory approach and also an ecological centre focusing on science and research. Therefore, the aim of this paper is to demonstrate this evolutionary and diverse nature of the museum through its key functions in society. My paper also seeks to establish how much the museum has truly established itself as a dynamic tool for education and research. What learning and research activities serve to bridge the gap between museums and their audiences? The article uses case studies from Botswana and Malawi to authenticate and support its arguments.
Relația dintre obiectele muzeale și datele într-o colecție digitală de fotografii etnografice
Authors: Tatai Orsolya
Published: December 2024

In the museum setting, various forms of data – written, visual, material, or digital – are pivotal for the preservation and display of cultural heritage. This research focuses on interpreting data as intangible elements within the museum environment, enveloping the exhibited or archived tangible objects. By referencing Arjun Appadurai’s concept of “thing” and its application to “data”, the study investigates how this data influences our perception and engagement with museum artifacts. Through a specific case study centered on an ethnographical photo collection, the research underscores the dynamic relationship between tangible objects and the intangible data that contextualizes and enhances our encounters with cultural heritage in museums.
Muzeu pentru Mileniul III
Authors: Chirilă Oana-Alexandra
Published: December 2024

In times when we are progressively trying to configure museum models focusing on the relationship with the public rather than the object, this article revisits two concepts that could prove useful in our endeavours: ‘third place’, stemming from urban planning and sociology, and ‘third space’, as defined by critical theory. Framing the museum as a ‘third place’ and a ‘third space’ at the same time, I posit, could help us not only to solidify our visitors’ pool but also to contribute substantially to the social health of our respective communities.
Goodwill, Morality and Legislation in Restitution & Provenance Politics; a Reflection on Customary Laws and Property Ownership in Africa
Authors: Thebele Winani
Published: December 2024

Calls for restitution and provenance research over colonial objects have embraced museums globally. The two theoretical undertakings complement one another. Governments, heritage institutions and individuals are reviewing the provenance of their colonial collections and returning them to descendant communities. Widely publicised return undertakings and ceremonies attest to this. Scholars and curators have revolutionised their thinking, approaches and writings with an intent to decolonize narratives associated with the colonial holdings. Conversations through seminars, conferences, workshops and political statements complement the efforts. However, the returns are usually presented as voluntary gestures, driven by morality, redress, equality, correction of colonial wrongs and calls for human rights. This article argues that there are also legal obligations as evidenced by developments in Europe and America today. The article methodologically interrogates three intertwined subjects: 1. the current state of affairs with Africa’s colonial heritage; 2. the customary laws on collective ownership of heritage by communities as a contributory catalyst to the migration of heritage; and 3. an ignored factor in the quest for repatriations and the development of national legal structures by states that hold colonial objects. The argument is that these should be balanced; the returns are not only based on morality and goodwill by hosting states, but are also enforced by legal obligations. The paper further argues that all stakeholders should be taken on board in provenance and restitutions, particularly the descendant communities, their wishes and customs. These present as part of ‘best museum practise’ and the decolonization narrative.
Modificări legislative în domeniul muzeal și al protejării patrimoniului
Authors: Vasile Alis
Published: December 2024

The paper is a critical overview of the recently issued regulations (December 2022 – June 2024) on movable cultural heritage and museums in Romania. The main elements of the new regulations reinforce the advisory role of the scientific external body of the Romanian Ministry of Culture, the National Commission for Museums and Collections, administrative procedures for declaring cultural goods as national treasure and for the pre-emption right of the Romanian state in acquiring cultural goods classified as national treasure, as well as new sanctioning competences for the Romanian Police, in the field of national movable cultural heritage.
Neuropsychiatric Considerations for the Assessment of Psychogenic Non-epileptic Seizures in Youth: A Trainee Perspective
Authors: Silver William , Hauptman Aaron
Published: December 2024

Psychogenic nonepileptic seizures (PNES) are paroxysmal events that present the outward appearance of epileptic seizures but lack underlying epileptiform discharges. Up to 20% of children who undergo video electroencephalogram monitoring have PNES. The International League Against Epilepsy (ILAE) provides guidelines for the assessment and management of pediatric PNES. PNES is also often comorbid with neurodevelopmental disorders. Distinguishing between PNES, epileptic seizures, and other neuropsychiatric conditions can be challenging. This article highlights some of the diagnostic challenges, utilizing ILAE guidelines, from the perspective of a developmental neuropsychiatry trainee.
Technological Analysis of Pedagogical Practices in Colombian Public Schools: A Case Study of Valledupar in Mathematics, Spanish Language, and Natural Sciences
Authors: Wilcar Damian Cifuentes Alvarez  , Maria Alexandra Chirino Kammerer  , Freddy Enrique Sierra Carrillo  , Roberto Antonio Martínez Medina
Published: December 2024

Within the framework of the institutional improvement of the Popular University of Cesar, and seeking to replicate what was done in 2012, by the Jorge Tadeo Lozano University of Colombia, which carried out a project called Pedagogies on the Move, which is presented as "an opportunity to reflect on and support the pedagogical work of schools". In 2013, significant progress had been made in the knowledge of 16 schools in 9 different regions of the country. The objective of this research is to understand the world of pedagogical practices within the regular classrooms of basic primary and secondary education of Colombian public schools in Valledupar, Cauca, Caldas, Córdoba, Santander and Valle del Cauca, in the fifth, sixth and seventh grades. It seeks to inquire about: The pedagogical logics - what it means to learn and how this process is promoted - that guide teachers; the pedagogical practices they carry out in classes of mother tongue (Spanish), mathematics or natural sciences. Under the epistemological and methodological approaches of ethnography, based on the assumption that the teacher is not a mere executor of pedagogical norms or curricular guidelines, nor a solitary subject who invents them, nor does he limit himself to listening to what his administrative superiors or his expert advisors tell him. In addition to this, that each teaching practice, for each one, is associated with its own pedagogical logic, the daily teaching practices in their own schools are made known.
Complex Impedance Spectroscopy Analysis of Quaternary Ionic Glass System
Authors: V A Adhwaryu  , H P Raval  , P B Shukla  , D K Kanchan
Published: December 2024

An investigation uses the rapid quench method to prepare and characterise a quaternary glass system with the chemical composition ????????−????2????−????2????3−????2????5. Alkali metal ion (????), metal oxides (????2????), boron oxide (????2????3), and phosphorus oxide (????2????5) make up the composition of the glass system. This points to a complicated network in which alkali metal oxides alter the network structure and phosphorus and boron serve as mixed network formers.The rapid quench approach was used to prepare the glasses, which usually entails rapidly cooling a molten material to inhibit crystallisation and encourage the creation of an amorphous (glassy) structure. X-ray diffraction (XRD) was utilised for structural characterisation to analyse the degree of crystallinity.
Highly Sensitive RF Energy Harvesting System for Wireless Protocol in IoT Devices
Authors: Abhay R Kasetwar  , Sanjay L Badjate  , Vicky Butram  , Milind S. Narlawar  , Sagar Pradhan  , Rahul Pethe
Published: December 2024

In this paper, a co-design methodology for Radio frequency (RF) energy harvester and an ultra-low Power Management Unit (PMU) is developed in order to achieve highest system efficiency. Antenna-Converter interface model is analyzed as it plays a crucial role in order to achieve better sensitivity. Matching network realized between the interface model act as a voltage magnifier circuit as well as provides interface impedance matching. The designed system harvests energy for operating PMU whenever RF power in the environment is around -30 dBm with power conversion efficiency of 38 %. The complete schematic is simulated using Advance Design System (ADS) tool which finally generates regulated DC output voltage of 500 mV with a load current of 5 mA.
Development of a Buyer Persona Strategy for the Design of a Digital Platform Focused on the Livestock Sector in the Colombian Caribbean Zone
Authors: Gustavo Adolfo Ramos Gélvez  , Cindy Lorena García Pinto  , Fanny Matilde Pinzon Candelario  , Lina María Wadnípar Cano  , Yaneth de Jesús Galindo Mora  , Yamile Rojas Mora  , Luis Miguel Barreto Lopez  , Claudia María Vitola Otálora
Published: December 2024

The research proposal is aimed at strengthening animal production in the Caribbean area, through e-extension consultancy mediated by the use of ICT, taking into account the problems faced by this sector in terms of access to information and use of new technologies to improve their production and business processes. With the creation of a Buyer persona, we seek to identify the type of population that would be willing to be part of a digital platform, and the type of content to provide, seeking to bring the academy closer to the productive sector, thus being able to provide solutions to real problems, allowing to test the knowledge acquired by students with the support of teachers.
For this reason, it is proposed to develop a buyer persona methodology, through the use of surveys, to determine our client and service to be targeted in the diagnosis of the livestock sector in the Caribbean zone, which allows to recognize the priorities of the sector in livestock consulting and support of these, being such an important link in the economy of the area and for this,  students and teachers of the Zootechnical program of the Universidad Nacional Abierta y a Distancia - UNAD, will carry out the implementation of the methodology described here. With the creation of the buyer persona, it is intended to develop in the future a technological tool from the analysis carried out in order to deliver a multimedia product where teachers and students work as a team to provide support to this sector.
An Ensemble Based Clustering and Classification Framework for Prediction of Agricultural Crop Yield
Authors: Udhaya Priya J  , Dr. K. Nirmala
Published: December 2024

Agriculture, a critical sector in India's economy, is deeply influenced by various factors such as climate, soil quality, irrigation, and economic conditions. Accurate prediction of crop yield is essential for both farmers and businesses operating in the agricultural supply chain. Historical data on crop yields can inform decision-making, reduce risks, and enhance the efficiency of supply chain operations, including the scheduling of production and the marketing of agricultural products. However, existing methods for predicting crop yield often face challenges in accuracy and generalizability.This study proposes an ensemble-based clustering and classification framework to improve the prediction of agricultural crop yield. The framework includes three main components: (i) pre-processing of agricultural datasets, (ii) ensemble clustering using two optimization algorithms—Enhanced Artificial Bee Colony Optimization (EABCO) and Shuffled Frog Leaping Algorithm (SFLA), and (i) classification of clustered datasets using Enhanced K-Nearest Neighbor (KNN) classification. The proposed method aims to reduce the limitations farmers face in selecting suitable crops for specific regions and to enhance the accuracy of crop yield predictions by identifying key indicators of agricultural field heterogeneity.The framework was implemented in a Java environment and tested on datasets related to paddy crop yield. The performance of the proposed method was evaluated using accuracy, precision, recall, F-measure, and percentage error. The results demonstrate that the proposed EABCO-SFLA clustering ensemble, combined with Enhanced KNN classification, achieves higher accuracy (92.7%), improved precision (91.2%), better recall (90.6%), and a reduced percentage error (5.3%) compared to existing classifiers. This approach provides a more reliable prediction of crop yield, enabling better decision-making in agriculture and supply chain management.
Academic Achievements And Engagement With Students At Indian Business Schools Providing Hybrid Courses
Authors: Dr. Aravinda Reddy M N  , Dr Kiran Kumar Thoti  , Dr. Kumuda P.R  , Mr. V Narendhra  , Prof. Dr. Mohammad Asif Pasha
Published: December 2024

Studying the effects of the change is critical as educational institutions around the world deal with the confluence of traditional and online learning environments. The purpose of this research is to determine whether and how hybrid learning influences student happiness and success at Master Students. The study's overarching goal is to shed light on the complex interplay between factors including course materials, technology interfaces, and interactive modalities and student happiness. Simultaneously, it seeks to track how hybrid learning affects academic performance, specifically looking at test scores and total accomplishment. The purpose of this research is to examine, through examination of exam scores, how hybrid learning influences the happiness and academic success of students enrolled in Master Programs (such as MBA and PGDM) at B-Schools in India. A total of 202 students from Indian business schools were the intended subjects. Digital technology and online resources have the potential to impact student engagement, flexibility, and access to instructional materials through their incorporation into the learning process. To what degree, if any, hybrid learning improves master's students' happiness and performance in the classroom remains an open question.