bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Authors: Nakaya Takeo , Ogawa Seishi , Manabe Ichiro , Tanaka Masami , Sanada Masashi , Sato Toshiro , Taketo Makoto M. , Nakao Kazuki , Clevers Hans , Fukayama Masashi , Kuroda Masahiko , Nagai Ryozo
Published: March 2023

PDF file - 674KB, Experimental design for the sorting of stem cells and TA cells from the duodenum of Lgr5-GFP-IRES-CreERT mice (Lgr5 Cre+ Catnb+/lox(ex3) Klf5flox/flox, Lgr5 Cre+ Catnb+/lox(ex3) Klf5+/+, and Lgr5 Cre+ Klf5flox/flox) for mRNA expression microarray analysis.
Supplementary Methods, Figure Legends, Tables 1 - 5 from HNRNPAB Induces Epithelial–Mesenchymal Transition and Promotes Metastasis of Hepatocellular Carcinoma by Transcriptionally Activating SNAIL
Authors: Zhou Zheng-Jun , Dai Zhi , Zhou Shao-Lai , Hu Zhi-Qiang , Chen Qing , Zhao Yi-Ming , Shi Ying-Hong , Gao Qiang , Wu Wei-Zhong , Qiu Shuang-Jian , Zhou Jian , Fan Jia
Published: March 2023

PDF file - 209K, Supplementary Table S1. Clinicopathologic characteristics of HCC patients. Supplementary Table S2. Primer sequences used in this study. Supplementary Table S3. Primary antibodies used in western blot, immunohistochemistry and immunofluorescence tests. Supplementary Table S4. Correlation between hnRNPAB and Snail expression and clinicopathologic characteristics in HCC (n=323). Supplementary Table S5. Univariate and Multivariate analyses of prognostic factors with TTR and OS in HCC patients (n=323).
Supplementary Figure 5 from ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis
Authors: Bid Hemant K. , Roberts Ryan D. , Cam Maren , Audino Anthony , Kurmasheva Raushan T. , Lin Jiayuh , Houghton Peter J. , Cam Hakan
Published: March 2023

PDF file - 111K, deltaNp63alpha regulates migration, VEGF and HRE promoter activity in a STAT3-dependent manner.
Supplementary Methods, Figures 1-3 from Impact of Tumor Progression on Cancer Incidence Curves
Authors: Luebeck E. Georg , Curtius Kit , Jeon Jihyoun , Hazelton William D.
Published: March 2023

PDF file - 8.8MB
Supplementary Tables 1 - 4 from CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer
Authors: Colbert Lauren E. , Petrova Aleksandra V. , Fisher Sarah B. , Pantazides Brooke G. , Madden Matthew Z. , Hardy Claire W. , Warren Matthew D. , Pan Yunfeng , Nagaraju Ganji P. , Liu Elaine A. , Saka Burcu , Hall William A. , Shelton Joseph W. , Gandhi Khanjan , Pauly Rini , Kowalski Jeanne , Kooby David A. , El-Rayes Bassel F. , Staley Charles A. , Adsay N. Volkan , Curran Walter J. , Landry Jerome C. , Maithel Shishir K. , Yu David S.
Published: March 2023

XLS file - 675KB, Full Results of Primary Gemcitabine Sensitivity Screen (S1). Known DNA Damage Response Genes Identified as Hits in Gemcitabine Sensitivity Screen (S2). Dysregulation, Differential Expression, and Literature RNAi Cross-Reference for Known DDR Genes and Select Hits (S3). Selected Top 15% of Gemcitabine Sensitivity Genes Tested on Secondary Screen (S4).
Supplementary Figures 1 - 6 from CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer
Authors: Colbert Lauren E. , Petrova Aleksandra V. , Fisher Sarah B. , Pantazides Brooke G. , Madden Matthew Z. , Hardy Claire W. , Warren Matthew D. , Pan Yunfeng , Nagaraju Ganji P. , Liu Elaine A. , Saka Burcu , Hall William A. , Shelton Joseph W. , Gandhi Khanjan , Pauly Rini , Kowalski Jeanne , Kooby David A. , El-Rayes Bassel F. , Staley Charles A. , Adsay N. Volkan , Curran Walter J. , Landry Jerome C. , Maithel Shishir K. , Yu David S.
Published: March 2023

PDF file - 981KB, Representative Immunohistochemistry for CHD7 Expression in Primary Tumor Tissue (S1). Network Analysis via MetaCore ExPlain Process Network Analysis for genes involved in CHK1, CDC25A, AURKB, PLK1, HUS1 pathway (S2). CHD7 Knockdown Causes Gemcitabine Sensitization (S3). Mice with Xenograft Tumors Showed No Significant Difference in Body Weight (S4). CHD7 Knockdown Effect on Cell Cycle (S5). Gemcitabine Does Not Significantly Change CHD7 Protein Levels in Cells (S6).
Supplementary Table 1 from CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Authors: Ooi Aikseng , Dykema Karl , Ansari Asif , Petillo David , Snider John , Kahnoski Richard , Anema John , Craig David , Carpten John , Teh Bin-Tean , Furge Kyle A.
Published: March 2023

XLSX file - 186K, Somatic mutation in PRCC2
Supplementary Figure 3 from CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Authors: Ooi Aikseng , Dykema Karl , Ansari Asif , Petillo David , Snider John , Kahnoski Richard , Anema John , Craig David , Carpten John , Teh Bin-Tean , Furge Kyle A.
Published: March 2023

PDF file - 197K, The pGL4luc2P-NRF2-ARE-Hygro construct (Promega)
Supplementary Figure Legend from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer
Authors: McCormack Emmet , Silden Elisabeth , West Richard M. , Pavlin Tina , Micklem David R. , Lorens James B. , Haug Bengt Erik , Cooper Michael E. , Gjertsen Bjørn Tore
Published: March 2023

PDF file - 99K
Supplementary Figure 1 from CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Authors: Ooi Aikseng , Dykema Karl , Ansari Asif , Petillo David , Snider John , Kahnoski Richard , Anema John , Craig David , Carpten John , Teh Bin-Tean , Furge Kyle A.
Published: March 2023

PDF file - 772K, Knowledge-guided strategy of driver mutation discovery for NRF2 activation in sporadic PRCC2
Supplementary Figure 6 from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer
Authors: McCormack Emmet , Silden Elisabeth , West Richard M. , Pavlin Tina , Micklem David R. , Lorens James B. , Haug Bengt Erik , Cooper Michael E. , Gjertsen Bjørn Tore
Published: March 2023

PDF file - 1949K, Flow cytometry quantification of NTR/CytoCy5S fluorescence in NB4 cells � NTR � CytoCy5S.
Supplementary Tables 1 - 2 from Activation of HIF2α in Kidney Proximal Tubule Cells Causes Abnormal Glycogen Deposition but not Tumorigenesis
Authors: Fu Leiping , Wang Gang , Shevchuk Maria M. , Nanus David M. , Gudas Lorraine J.
Published: March 2023

PDF file - 63K, Supplemental tables for GGT-HIF2αM3 transcript quantification
Supplementary Figure 1 from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer
Authors: McCormack Emmet , Silden Elisabeth , West Richard M. , Pavlin Tina , Micklem David R. , Lorens James B. , Haug Bengt Erik , Cooper Michael E. , Gjertsen Bjørn Tore
Published: March 2023

PDF file - 402K, Synthesis, mechanism and spectral characteristics of CytoCy5S.
Supplementary Figure 5 from Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression
Authors: Keune Willem-Jan , Sims Andrew H. , Jones David R. , Bultsma Yvette , Lynch James T. , Jirström Karin , Landberg Goran , Divecha Nullin
Published: March 2023

PDF file - 89K, A. Gene expression profiles of widely used breast tumour cell lines were extracted from three different data sets, normalised and clustered into the designated molecular subtypes. The expression of PIP4K2A, 2B and 2C are graphically shown below. B. Box plots representing the expression of PIP4K2B in the three molecular subtypes determine by cluster analysis. C. Expression of PIP4K2B in normal cells (MCF10A) and luminal cells (MCF7) and ERBB2 positive cells (ZR-75).
Supplementary Figure 4 from Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression
Authors: Keune Willem-Jan , Sims Andrew H. , Jones David R. , Bultsma Yvette , Lynch James T. , Jirström Karin , Landberg Goran , Divecha Nullin
Published: March 2023

PDF file - 60K, A. The gene expression profiles of PIP4K2B in normal and tumour tissues were extracted (GSE10780) and compared. PIP4K2B levels were significantly lower in tumor samples (P=0.04) B. Breast tumour samples from 17 data sets representing 2999 tumours were clustered into the molecular subtypes shown. The PIP4K2B expressions are shown as box plots. Significant differences were determined between different subtyps and the p values for the comparisons are shown in the inset.
Supplementary Figure 2 from NADPH Oxidase NOX4 Supports Renal Tumorigenesis by Promoting the Expression and Nuclear Accumulation of HIF2α
Authors: Gregg Jennifer L. , Turner Robert M. , Chang Guimin , Joshi Disha , Zhan Ye , Chen Li , Maranchie Jodi K.
Published: March 2023

PDF file - 376K, Supplemental Figure 2. Characterization of 786-0 cells stably transfected with the human, full-length Nox4 cDNA. (a) Morphology of 786-0 cells following exogenous expression of Nox4 reveals smaller, denser, more-rounded appearance relative to parental 786-0 cells. (b) Cell viability assay. Equal numbers of untransfected cells or 786-0 Nox4 cells were plated in 96-well plates. After attachment, assay reagent was added, incubated at 37{degree sign}C, and the fluorescent signal read at 590 nm.
Supplementary Methods, Figure Legends, Table 1 from Activation of SOX2 Expression by BRD4-NUT Oncogenic Fusion Drives Neoplastic Transformation in NUT Midline Carcinoma
Authors: Wang Ranran , Liu Wei , Helfer Christine M. , Bradner James E. , Hornick Jason L. , Janicki Susan M. , French Christopher A. , You Jianxin
Published: March 2023

PDF file - 122KB, Supplementary Table S1. Real-time PCR primers used in this study.
Supplementary Figure Legends from Chromosome Instability Modulated by BMI1–AURKA Signaling Drives Progression in Head and Neck Cancer
Authors: Chou Chun-Hung , Yang Neng-Kai , Liu Ting-Yun , Tai Shyh-Kuan , Hsu Dennis Shin-Shian , Chen Ya-Wei , Chen Yann-Jang , Chang Cheng-Chi , Tzeng Cheng-Hwai , Yang Muh-Hwa
Published: March 2023

PDF file - 104KB
Supplementary Figure and Table Legends from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma
Authors: Santo Evan E. , Stroeken Peter , Sluis Peter V. , Koster Jan , Versteeg Rogier , Westerhout Ellen M.
Published: March 2023

Supplementary Figure and Table Legends PDF file - 63K, Legend for Supplementary Figures S1-S5 and Supplementary Table S1
Supplementary Figure 2 from Trask Loss Enhances Tumorigenic Growth by Liberating Integrin Signaling and Growth Factor Receptor Cross-Talk in Unanchored Cells
Authors: Spassov Danislav S. , Wong Ching Hang , Wong Sunny Y. , Reiter Jeremy F. , Moasser Mark M.
Published: March 2023

PDF file - 77K, Src activity in SmoM2 induced skin neoplasia
Supplementary Figure 1 from Trask Loss Enhances Tumorigenic Growth by Liberating Integrin Signaling and Growth Factor Receptor Cross-Talk in Unanchored Cells
Authors: Spassov Danislav S. , Wong Ching Hang , Wong Sunny Y. , Reiter Jeremy F. , Moasser Mark M.
Published: March 2023

PDF file - 127K, Lung metastases in PyMT mice
Supplementary Methods from Monoclonal Antibody Targeting of the Cell Surface Molecule TM4SF5 Inhibits the Growth of Hepatocellular Carcinoma
Authors: Kwon Sanghoon , Choi Kyung-Chan , Kim Young-Eun , Ha Yang-Wha , Kim Dongbum , Park Byoung Kwon , Wu Guang , Kim Doo-Sik , Lee Younghee , Kwon Hyung-Joo
Published: March 2023

PDF file - 158KB
Supplementary Figure 5 from Redox Modulation of Adjacent Thiols in VLA-4 by AS101 Converts Myeloid Leukemia Cells from a Drug-Resistant to Drug-Sensitive State
Authors: Layani-Bazar Adi , Skornick Itai , Berrebi Alain , Pauker Maor H. , Noy Elad , Silberman Alon , Albeck Michael , Longo Dan L. , Kalechman Yona , Sredni Benjamin
Published: March 2023

PDF file - 1086K, Fig. S5: Knocking out VLA-4 in mouse myelomonocytic leukemia cells or human AML leukemic cells induces drug sensitivity which is not further enhanced by AS101.
Supplementary Figure 2 from Redox Modulation of Adjacent Thiols in VLA-4 by AS101 Converts Myeloid Leukemia Cells from a Drug-Resistant to Drug-Sensitive State
Authors: Layani-Bazar Adi , Skornick Itai , Berrebi Alain , Pauker Maor H. , Noy Elad , Silberman Alon , Albeck Michael , Longo Dan L. , Kalechman Yona , Sredni Benjamin
Published: March 2023

PDF file - 766K, Fig. S2: Chemoresistance of myelomonocytic leukemia cells induced by BM Stromal cells is abrogated by AS101.
Supplementary Figure 1 from A Circadian Clock Transcription Model for the Personalization of Cancer Chronotherapy
Authors: Li Xiao-Mei , Mohammad-Djafari Ali , Dumitru Mircea , Dulong Sandrine , Filipski Elisabeth , Siffroi-Fernandez Sandrine , Mteyrek Ali , Scaglione Francesco , Guettier Catherine , Delaunay Franck , Lévi Francis
Published: March 2023

PDF file - 85K, Scheme of the mathematical model, describing the linear relation between input data (mRNA expression of Rev-erbalpha and Bmal1) and output data (body weight loss - BWL).
Supplementary Figures 1 - 5 from High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma
Authors: Crompton Brian D. , Carlton Anne L. , Thorner Aaron R. , Christie Amanda L. , Du Jinyan , Calicchio Monica L. , Rivera Miguel N. , Fleming Mark D. , Kohl Nancy E. , Kung Andrew L. , Stegmaier Kimberly
Published: March 2023

PDF file - 62K, Treatment of two Ewing sarcoma cell lines with A, dasatinib (SRC inhibitor) for 8 hours or B, PD0325901 (MEK inhibitor) for 72 hours eliminates phosphorylation of SRC and ERK, respectively (S1); Transduction with five FAK-directed shRNAs downregulate FAK expression compared to a control shRNA in the A673 Ewing sarcoma cell line (S2); Treatment of A673 and TC32 Ewing sarcoma cell lines with PF-562271 reduced cell growth (S3); Treatment of Ewing sarcoma cell lines with PF- 562271 impairs cell growth (S4); PYK2 is variably expressed in Ewing sarcoma cell lines (S5).
Supplementary Figure Legends from Human Rhomboid Family-1 Suppresses Oxygen-Independent Degradation of Hypoxia-Inducible Factor-1α in Breast Cancer
Authors: Zhou Zhuan , Liu Fangfang , Zhang Zhi-Song , Shu Feifei , Zheng Yangyang , Fu Li , Li Lu-Yuan
Published: March 2023

PDF file - 148KB
Supplementary Methods, Figure Legends from A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
Authors: Chang Yu-Hsiang , Connolly John , Shimasaki Noriko , Mimura Kousaku , Kono Koji , Campana Dario
Published: March 2023

PDF file - 298K, SF1. Cytokine/chemokine secretion of mock- and NKG2D-DAP10-CD3-transduced NK cells from 3 donors after incubation with a biotin-conjugated anti-NKG2D agonistic antibody (clone 1D11; eBioscience) and anti-biotin beads (MACSiBeads; Miltenyi Biotec) (see also Fig. 4 and Supplementary Table S1). Supplemental Movie. Live cell confocal photography of mock- (left panel) and NKG2D-DAP10-CD3-transduced NK cells (right panel) co-cultured U2 OS osteosarcoma cells. NK cells were labeled with PKH26 (Sigma) before culture and appear red. Microscopy was performed with a Nikon TE2000E2 microscope equipped with a Nikon C1Si confocal using 488nm and 561nm DPSS lasers for excitation. Temperature was maintained at 37oC and CO2 at 5% using an environmental control chamber. Images were acquired with a Nikon 40x 1.3 NA DIC objective every 30s for 2hr using Nikon EZC1 software. Imaris (Bitplane Scientific Software) was used to analyze speed and displacement of NK cells. Supplementary Table S1. Cytokine/chemokine secretion (mean � SD pg/mL) after stimulation of mock- or NKG2D-DAP10-CD3-transduced NK cells with anti-NKG2Da.
Supplementary Figure 3 from MyoD Is a Tumor Suppressor Gene in Medulloblastoma
Authors: Dey Joyoti , Dubuc Adrian M. , Pedro Kyle D. , Thirstrup Derek , Mecham Brig , Northcott Paul A. , Wu Xiaochong , Shih David , Tapscott Stephen J. , LeBlanc Michael , Taylor Michael D. , Olson James M.
Published: March 2023

PDF file - 1235K, MyoD is expressed in proliferating tumor cells in SmoA1, SmoA2 and Ptch conditional knock out medulloblastoma mouse models.
Supplementary Figure 9 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases
Authors: von Scheidt Bianca , Leung Patrick S.K. , Yong Michelle C.R. , Zhang Yu , Towne Jennifer E. , Smyth Mark J. , Teng Michele W.L.
Published: March 2023

PDF file - 96K, IL-23 expression is detected in MHCIIhiCD11c+CD11b+ cells but not in other populations in B16F10 tumor bearing lungs.
Supplementary Figure 3 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases
Authors: von Scheidt Bianca , Leung Patrick S.K. , Yong Michelle C.R. , Zhang Yu , Towne Jennifer E. , Smyth Mark J. , Teng Michele W.L.
Published: March 2023

PDF file - 84K, Combined anti-CD40/IL-23p19 mAb therapy suppresses established subcutaneous B16F10 tumors and is primarily dependent on T cells.
Supplementary Figures 1-8 from Cotargeting Androgen Receptor and Clusterin Delays Castrate-Resistant Prostate Cancer Progression by Inhibiting Adaptive Stress Response and AR Stability
Authors: Matsumoto Hiroaki , Yamamoto Yoshiaki , Shiota Masaki , Kuruma Hidetoshi , Beraldi Eliana , Matsuyama Hideyasu , Zoubeidi Amina , Gleave Martin
Published: March 2023

PDF - 359K, S1: Schema illustrating generation of CRPC and MDV3100 resistant tumors and cell lines. S2: CLU is induced by CSS, bicalutamide and MDV3100 in LNCaP cells. S3: CLU is induced by MDV3100 in time and dose dependent manner. S4: CLU knockdown synergistically enhances MDV3100-induced inhibition of C4-2 but not in PC-3 cell growth. S5: CLU silencing enhances MDV3100 effect on AR transcription activity. S6: CLU knockdown in combination with MDV3100 decreases AR protein levels. S7: Effect of CLU knockdown and MDV3100 on AR expression. S8: Effect of MDV3100 on HSF-1 transcriptional activity.
Supplementary Figure 6 from Epigenetic States of Cells of Origin and Tumor Evolution Drive Tumor-Initiating Cell Phenotype and Tumor Heterogeneity
Authors: Chow Kin-Hoe , Shin Dong-Mi , Jenkins Molly H. , Miller Emily E. , Shih David J. , Choi Seungbum , Low Benjamin E. , Philip Vivek , Rybinski Brad , Bronson Roderick T. , Taylor Michael D. , Yun Kyuson
Published: March 2023

H&E of tumor derived from injecting SMO;GFAP_cre tumor spheres.
Supplementary Figure 3 from CUL4A Induces Epithelial–Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression
Authors: Wang Yunshan , Wen Mingxin , Kwon Yongwon , Xu Yangyang , Liu Yueyong , Zhang Pengju , He Xiuquan , Wang Qin , Huang Yurong , Jen Kuang-Yu , LaBarge Mark A. , You Liang , Kogan Scott C. , Gray Joe W. , Mao Jian-Hua , Wei Guangwei
Published: March 2023

PDF file - 293K, Supplemental Figure 3. CUL4A promotes migration and invasion-metastasis of human normal mammary and cancer cells.
Supplementary Table 2 from Histone Chaperone CHAF1A Inhibits Differentiation and Promotes Aggressive Neuroblastoma
Authors: Barbieri Eveline , De Preter Katleen , Capasso Mario , Chen Zaowen , Hsu Danielle M. , Tonini Gian Paolo , Lefever Steve , Hicks John , Versteeg Rogier , Pession Andrea , Speleman Frank , Kim Eugene S. , Shohet Jason M.
Published: March 2023

XLSX file - 17K, Gene Ontology (GO) analysis of gene sets regulated by retinoic acid treatment.
Supplementary Figure 2 from Histone Chaperone CHAF1A Inhibits Differentiation and Promotes Aggressive Neuroblastoma
Authors: Barbieri Eveline , De Preter Katleen , Capasso Mario , Chen Zaowen , Hsu Danielle M. , Tonini Gian Paolo , Lefever Steve , Hicks John , Versteeg Rogier , Pession Andrea , Speleman Frank , Kim Eugene S. , Shohet Jason M.
Published: March 2023

PDF file - 53K, Effect of retinoic acid (RA) treatment on neuroblastoma cells.
Supplementary Table 1 from Oligodendrocyte Progenitor Cells Promote Neovascularization in Glioma by Disrupting the Blood–Brain Barrier
Authors: Huang Yujie , Hoffman Caitlin , Rajappa Prajwal , Kim Joon-Hyung , Hu Wenhuo , Huse Jason , Tang Zhongshu , Li Xuri , Weksler Babette , Bromberg Jacqueline , Lyden David C. , Greenfield Jeffrey P.
Published: March 2023

PDF - 93K, Authentication of Gl261 cells in related to "cell lines and mice lines" section in Materials and Methods.
Supplementary Methods and Supplementary Figures 1 through 14 from Oligodendrocyte Progenitor Cells Promote Neovascularization in Glioma by Disrupting the Blood–Brain Barrier
Authors: Huang Yujie , Hoffman Caitlin , Rajappa Prajwal , Kim Joon-Hyung , Hu Wenhuo , Huse Jason , Tang Zhongshu , Li Xuri , Weksler Babette , Bromberg Jacqueline , Lyden David C. , Greenfield Jeffrey P.
Published: March 2023

PDF - 9162K, Supplementary Methods: Including additional materials and methods Supplementary References: Including reference cited in the supplementary methods Supplementary Figures and Legends: S1. expression of stromal PDGFRalpha in various animal models. S2. Lineage and distribution of stromal PDGFRalpha+ cells. S3. Blood vessel density and pericytes in Gl261 glioma model. S4. Knocking out PDGFRalpha suppresses infiltration of BMDCs without affecting hematopoiesis. S5. Isolation and verification of OPCs from glioma S6. Endothelial tubule formation, endothelial sprouting, and permeability with GA-OPCs and astrocytes. S7. Proliferation of glioma cells with or without activated endothelial cells S8. Microarray analysis on GFP+/F4/80+ BMDCs S9. Hematopoiesis in PDGF-C -/- mice. S10. Astrocytes and endothelial cells express PDGF-C & pro-angiogenic profile of OPCs. S11. Blood vessel staining of grade III Patients S12. Expression of PDGF-C was analyzed in REMBRANDT database. S13. the correlation of PDGF-C with paitents' survial in Mesenchymal, Neural, Pro-neural subsets of GBM. S14. The correlation of PDGF-A and PDGF-B with paitent's survial in classical subset of GBM.
Supplementary Figure 1 from Unbiased Compound Screening Identifies Unexpected Drug Sensitivities and Novel Treatment Options for Gastrointestinal Stromal Tumors
Authors: Boichuk Sergei , Lee Derek J. , Mehalek Keith R. , Makielski Kathleen R. , Wozniak Agnieszka , Seneviratne Danushka S. , Korzeniewski Nina , Cuevas Rolando , Parry Joshua A. , Brown Matthew F. , Zewe James , Taguchi Takahiro , Kuan Shin-Fan , Schöffski Patrick , Debiec-Rychter Maria , Duensing Anette
Published: March 2023

PDF - 890K, The transcriptional inhibitor mithramycin A (MMA) is an effective inducer of GIST cell apoptosis and cell cycle arrest.
Supplementary Materials and Methods, Figures 1 - 2, Table 1 from NOTCH3 Signaling Regulates MUSASHI-1 Expression in Metastatic Colorectal Cancer Cells
Authors: Pastò Anna , Serafin Valentina , Pilotto Giorgia , Lago Claudia , Bellio Chiara , Trusolino Livio , Bertotti Andrea , Hoey Timothy , Plateroti Michelina , Esposito Giovanni , Pinazza Marica , Agostini Marco , Nitti Donato , Amadori Alberto , Indraccolo Stefano
Published: March 2023

PDF file - 146KB, Figure S1. Notch2/3 neutralization impairs Notch signaling in CRC cells. Figure S2. Study of the Msi-1 promoter activity in vitro. Table S1: primer sequences.
Data Supplement from Cancer Affects microRNA Expression, Release, and Function in Cardiac and Skeletal Muscle
Authors: Chen Daohong , Goswami Chirayu P. , Burnett Riesa M. , Anjanappa Manjushree , Bhat-Nakshatri Poornima , Muller William , Nakshatri Harikrishna
Published: March 2023

Supplementary Figure S1. miR-486 expression analysis.
Supplementary Tables 1 - 4 from Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging
Authors: Allen Michael D. , Luong Phuong , Hudson Chantelle , Leyton Julius , Delage Barbara , Ghazaly Essam , Cutts Rosalind , Yuan Ming , Syed Nelofer , Lo Nigro Cristiana , Lattanzio Laura , Chmielewska-Kassassir Malgorzata , Tomlinson Ian , Roylance Rebecca , Whitaker Hayley C. , Warren Anne Y. , Neal David , Frezza Christian , Beltran Luis , Jones Louise J. , Chelala Claude , Wu Bor-Wen , Bomalaski John S. , Jackson Robert C. , Lu Yong-Jie , Crook Tim , Lemoine Nicholas R. , Mather Stephen , Foster Julie , Sosabowski Jane , Avril Norbert , Li Chien-Feng , Szlosarek Peter W.
Published: March 2023

PDF file - 198K, Table S1 Correlation between ASS1 expression and various clinicopathological factors. Table S2 Univariate log-rank analysis for disease-specific survival and metastasis-free survival. Table S3 Correlation between ASS1 IHC and pyrosequencing of primary bladder cases. Table S4 Combination index (CI) analysis.
Supplementary Methods from Small Molecule Agonists of PPAR-γ Exert Therapeutic Effects in Esophageal Cancer
Authors: Sawayama Hiroshi , Ishimoto Takatsugu , Watanabe Masayuki , Yoshida Naoya , Sugihara Hidetaka , Kurashige Junji , Hirashima Kotaro , Iwatsuki Masaaki , Baba Yoshifumi , Oki Eiji , Morita Masaru , Shiose Yoshinobu , Baba Hideo
Published: March 2023

PDF file - 165K
Supplementary Figure 4 from shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer
Authors: Deng Tao , Liu Jeff C. , Chung Philip E.D. , Uehling David , Aman Ahmed , Joseph Babu , Ketela Troy , Jiang Zhe , Schachter Nathan F. , Rottapel Robert , Egan Sean E. , Al-awar Rima , Moffat Jason , Zacksenhaus Eldad
Published: March 2023

PDF file - 131KB, Supplementary Figure S4 shows the effect of autophagy inhibitors CQ and 5-MA on proliferation and survival of HER2+ mouse and human breast cancer cell lines.
Supplementary Figure 4 from Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer
Authors: Meeker Stacey , Seamons Audrey , Paik Jisun , Treuting Piper M. , Brabb Thea , Grady William M. , Maggio-Price Lillian
Published: March 2023

PDF file - 103K, High dietary vitamin D decreases expression of proinflammatory and chemotactic cytokines in proximal colon tissue and feces 1 week post H. bilis-infection.
Supplementary Figure 3 from shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer
Authors: Deng Tao , Liu Jeff C. , Chung Philip E.D. , Uehling David , Aman Ahmed , Joseph Babu , Ketela Troy , Jiang Zhe , Schachter Nathan F. , Rottapel Robert , Egan Sean E. , Al-awar Rima , Moffat Jason , Zacksenhaus Eldad
Published: March 2023

PDF file - 55KB, Supplementary Figure S3 shows expression of kinase hits in primary and secondary Her2/Neu tumor cells from RNA profiling analysis.
Supplementary Figure 2 from Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer
Authors: Meeker Stacey , Seamons Audrey , Paik Jisun , Treuting Piper M. , Brabb Thea , Grady William M. , Maggio-Price Lillian
Published: March 2023

PDF file - 63K, High dietary vitamin D decreases diarrhea in H. bilis-infected Smad3-/- mice.
Supplementary Figure S5 from LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase
Authors: Peng Hongzhuang , Talebzadeh-Farrooji Mehdi , Osborne Michael J. , Prokop Jeremy W. , McDonald Paul C. , Karar Jayashree , Hou Zhaoyuan , He Mei , Kebebew Electron , Orntoft Torben , Herlyn Meenhard , Caton Andrew J. , Fredericks William , Malkowicz Bruce , Paterno Christopher S. , Carolin Alexandra S. , Speicher David W. , Skordalakes Emmanuel , Huang Qihong , Dedhar Shoukat , Borden Katherine L.B. , Rauscher Frank J.
Published: March 2023

Asymmetry in electrostatic surface of PINCH LIM1 and LIMD2 domains.
Data Supplement from BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity
Authors: Cao Yuan , Slaney Clare Y. , Bidwell Bradley N. , Parker Belinda S. , Johnstone Cameron N. , Rautela Jai , Eckhardt Bedrich L. , Anderson Robin L.
Published: March 2023

Supplementary Figure 1. BMP4 regulates G-CSF in the weakly metastatic EO771 cells.
Data Supplement from BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity
Authors: Cao Yuan , Slaney Clare Y. , Bidwell Bradley N. , Parker Belinda S. , Johnstone Cameron N. , Rautela Jai , Eckhardt Bedrich L. , Anderson Robin L.
Published: March 2023

Supplementary Figure 3. Effect of BMP4 on the phenotype of 4T1.2 cells.
Supplementary Figure Legends and References from LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase
Authors: Peng Hongzhuang , Talebzadeh-Farrooji Mehdi , Osborne Michael J. , Prokop Jeremy W. , McDonald Paul C. , Karar Jayashree , Hou Zhaoyuan , He Mei , Kebebew Electron , Orntoft Torben , Herlyn Meenhard , Caton Andrew J. , Fredericks William , Malkowicz Bruce , Paterno Christopher S. , Carolin Alexandra S. , Speicher David W. , Skordalakes Emmanuel , Huang Qihong , Dedhar Shoukat , Borden Katherine L.B. , Rauscher Frank J.
Published: March 2023

Legend for Supplementary Figures S1-S6. Also includes Supplementary References.
Supplementary Figure 2 from Vaccine-Mediated Immunotherapy Directed against a Transcription Factor Driving the Metastatic Process
Authors: Ardiani Andressa , Gameiro Sofia R. , Palena Claudia , Hamilton Duane H. , Kwilas Anna , King Thomas H. , Schlom Jeffrey , Hodge James W.
Published: March 2023

PDF file - 358KB, Expression of EMT marker expression in primary tumor and lung metastases.
Supplementary Figure 4 from Apoptosis Imaging for Monitoring DR5 Antibody Accumulation and Pharmacodynamics in Brain Tumors Noninvasively
Authors: Weber Thomas G. , Osl Franz , Renner Anja , Pöschinger Thomas , Galbán Stefanie , Rehemtulla Alnawaz , Scheuer Werner
Published: March 2023

PDF file - 186KB, Supplementary Figure 4 - Antibody penetration is enhanced in U87-Luc and U251 brain xenograft tumors indicating BBB disruption.
Supplementary Figure 2 from Loss of Androgen Receptor Expression Promotes a Stem-like Cell Phenotype in Prostate Cancer through STAT3 Signaling
Authors: Schroeder Anne , Herrmann Andreas , Cherryholmes Gregory , Kowolik Claudia , Buettner Ralf , Pal Sumanta , Yu Hua , Müller-Newen Gerhard , Jove Richard
Published: March 2023

PDF file - 5546K, Supplementary Fig.2: STAT3 activation is associated with upregulated CSC marker expression.
Supplementary Figure Legend from Novel Mechanism of MDA-7/IL-24 Cancer-Specific Apoptosis through SARI Induction
Authors: Dash Rupesh , Bhoopathi Praveen , Das Swadesh K. , Sarkar Siddik , Emdad Luni , Dasgupta Santanu , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 66K
Supplementary Figure 4 from Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1
Authors: Bronisz Agnieszka , Wang Yan , Nowicki Michal O. , Peruzzi Pierpaolo , Ansari Khairul I. , Ogawa Daisuke , Balaj Leonora , De Rienzo Gianluca , Mineo Marco , Nakano Ichiro , Ostrowski Michael C. , Hochberg Fred , Weissleder Ralph , Lawler Sean E. , Chiocca E. Antonio , Godlewski Jakub
Published: March 2023

PDF file - 98K, FIGURE S4 related to FIGURE 5. Visualization of GBM-derived EVs uptake.
Data Supplement from AR-Regulated TWEAK-FN14 Pathway Promotes Prostate Cancer Bone Metastasis
Authors: Yin JuanJuan , Liu Yen-Nien , Tillman Heather , Barrett Ben , Hewitt Stephen , Ylaya Kris , Fang Lei , Lake Ross , Corey Eva , Morrissey Colm , Vessella Robert , Kelly Kathleen
Published: March 2023

Supplemental Figure 3. (A) Western blot analysis of the DU145/RasB1IÎºBÎ±SR cell line, with or without prior doxycycline induction for 2 days, harvested at various time points (min) after TWEAK treatment (50ng/ml) and assayed for the proteins indicated. (B) In vitro growth of the DU145/RasB1IÎºBÎ±SR cell line with and without prior doxycycline induction. *p<0.05. (C) Average body weight of mice bearing DU145/RasB1IÎºBÎ±SR tumors in mice fed with doxycycline on day 0 (n=9) or day 14(n=9). **p<0.01 vs control (n=8). (D) Western blot analysis of Fn14, IKKB and NIK levels in DU145/RasB1Fn14KD cell lines rescued by re-expression of Fn14, IKKBS177E S188E , and NIKâˆ†T3.
Supplementary Figure 4 from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth
Authors: Barceló Carles , Paco Noelia , Morell Mireia , Alvarez-Moya Blanca , Bota-Rabassedas Neus , Jaumot Montserrat , Vilardell Felip , Capella Gabriel , Agell Neus
Published: March 2023

PDF file - 31K, Fig. S4. Treatment with PKC inhibitor Edelfosine inhibits tumor growth of HAKRASG12V in a Ser181 KRAS phosphorylation-dependent fashion.
Supplementary Materials and Methods, Figures 1 - 14, Table 1 from PCAT-1, a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer
Authors: Prensner John R. , Chen Wei , Iyer Matthew K. , Cao Qi , Ma Teng , Han Sumin , Sahu Anirban , Malik Rohit , Wilder-Romans Kari , Navone Nora , Logothetis Christopher J. , Araujo John C. , Pisters Louis L. , Tewari Ashutosh K. , Canman Christine E. , Knudsen Karen E. , Kitabayashi Naoki , Rubin Mark A. , Demichelis Francesca , Lawrence Theodore S. , Chinnaiyan Arul M. , Feng Felix Y.
Published: March 2023

PDF file - 2687KB, Supplementary Figure S1: Effect of PCAT-1 on RAD51 foci formation. Supplementary Figure S2: PCAT-1 impairs homologous recombination. Supplementary Figure S3: PCAT-1 expression alters gamma-H2AX formation. Supplementary Figure S4: PCAT-1 expression effects clonogenic survival when treated with PARP inhibitors Olaparib or ABT-888. Supplementary Figure S5: PCAT-1 expression effects clonogenic survival when treated with ionizing radiation. Supplementary Figure S6: Treatment of PCAT-1 isogenic cells with ABT-888. Supplementary Figure S7: PCAT-1 overexpression in RWPE engenders sensitivity to genotoxic stress. Supplementary Figure 8: BRCA2 knockdown rescues RAD51 foci formation in LNCAP shPCAT1 cells after PARP inhibition. Supplementary Figure 9: PCAT-1 expression does not impact cell cycle distribution. Supplementary Figure S10: Effect of PCAT-1 in vivo on Olaparib treatment. Supplementary Figure S11: PCAT-1 does not operate via an epigenetic or STAU1-based mechanism. Supplementary Figure 12: PCAT-1 is cytoplasmic and effects target mRNA stability. Supplementary Figure 13: PCAT-1 overexpression in RWPE cells. Supplementary Figure 14: A model of PCAT-1 function in homologous recombination in prostate cancer. Supplementary Table 1: Primer Pairs used in this study.
Supplementary Methods from Bcl2 Induces DNA Replication Stress by Inhibiting Ribonucleotide Reductase
Authors: Xie Maohua , Yen Yun , Owonikoko Taofeek K. , Ramalingam Suresh S. , Khuri Fadlo R. , Curran Walter J. , Doetsch Paul W. , Deng Xingming
Published: March 2023

PDF file - 37K
Data Supplement from Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Authors: Tchaicha Jeremy H. , Akbay Esra A. , Altabef Abigail , Mikse Oliver R. , Kikuchi Eiki , Rhee Kevin , Liao Rachel G. , Bronson Roderick T. , Sholl Lynette M. , Meyerson Matthew , Hammerman Peter S. , Wong Kwok-Kin
Published: March 2023

Supplemental Figure 3. Extracellular Domain FGFR2 mutant mouse IHC.
Supplementary Figure 4 from Maintaining Glycogen Synthase Kinase-3 Activity Is Critical for mTOR Kinase Inhibitors to Inhibit Cancer Cell Growth
Authors: Koo Junghui , Yue Ping , Gal Anthony A. , Khuri Fadlo R. , Sun Shi-Yong
Published: March 2023

PDF file - 213KB, Effects of INK128 and AZD8055 on decreasing cyclin D1 levels and on suppressing mTOR signaling in human NSCLC cell lines with varied sensitivities to TORKinibs.
Supplementary Materials and Methods from Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53
Authors: Zhang Shengliang , Zhou Lanlan , Hong Bo , van den Heuvel A. Pieter J. , Prabhu Varun V. , Warfel Noel A. , Kline Christina Leah B. , Dicker David T. , Kopelovich Levy , El-Deiry Wafik S.
Published: March 2023

Supplementary Materials and Methods
Supplementary Figure Legends from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

PDF file - 84K
Supplementary Figure 7 from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

PDF file - 30K, Mir-221 expression decrease mRNA expression levels of SOCS3 or IRF2.
Supplementary Figure 6 from Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3
Authors: Kneitz Burkhard , Krebs Markus , Kalogirou Charis , Schubert Maria , Joniau Steven , van Poppel Hein , Lerut Evelyne , Kneitz Susanne , Scholz Claus Jürgen , Ströbel Philipp , Gessler Manfred , Riedmiller Hubertus , Spahn Martin
Published: March 2023

PDF file - 30K, Stable miR-221 expression in PC-3 clones mediates growth inhibition and activates genes involved in the interferon signaling pathway.
Supplementary Tables 1 - 10 from Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
Authors: Wang Bin , Wang Qiang , Wang Zhe , Jiang Jun , Yu Shi-Cang , Ping Yi-Fang , Yang Jing , Xu Sen-Lin , Ye Xian-Zong , Xu Chuan , Yang Lang , Qian Cheng , Wang Ji Ming , Cui You-Hong , Zhang Xia , Bian Xiu-Wu
Published: March 2023

Table S1. The levels of ALDH1+ cells and CD56+ cells and the clinical parameters of breast cancers. Table S2. Univariate analysis of potential prognostic factors for the ALDH1low and ALDH1high subgroups of breast cancers. Table S3. Multivariate analysis of potential prognostic factors for the ALDH1low and ALDH1high subgroups of breast cancers. Table S4. Patient characteristics of primary breast cancers for culture. Table S5. Antibodies used in the study. Table S6. Primers used for cloning coding sequence of MICA and MICB. Table S7. Primers sequences that were used in the qRT-PCR. Table S8. Small interference RNA sequences for knockdown of MICA and MICB expression. Table S9. Primers used for cloning of MICA-3â€™UTR and MICB-3â€™UTR. Table S10. Nucleotide sequences of MICA-3â€™UTR and MICB-3â€™UTR with mutant binding sites for miRNA-20a.
Supplementary Figure 5 from Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
Authors: Wang Bin , Wang Qiang , Wang Zhe , Jiang Jun , Yu Shi-Cang , Ping Yi-Fang , Yang Jing , Xu Sen-Lin , Ye Xian-Zong , Xu Chuan , Yang Lang , Qian Cheng , Wang Ji Ming , Cui You-Hong , Zhang Xia , Bian Xiu-Wu
Published: March 2023

Knockdown of MICA or MICB in non-BCSCs.
Supplementary Figure 7 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Authors: Guillemette Shawna , Branagan Amy , Peng Min , Dhruva Aashana , Schärer Orlando D. , Cantor Sharon B.
Published: March 2023

PDF file - 57K, Supplemental Figure 7. Mutations in FANCJ and MMR loci occur in melanoma genomes
Supplementary Figure 7 from GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2
Authors: Yang Liquan , Friedland Scott , Corson Nancy , Xu Lei
Published: March 2023

PDF file - 1762K, This figure shows the distribution pattern of Nf fragments in MC-1 cells.
Supplemental Table 1 from The Alarmin HMGN1 Contributes to Antitumor Immunity and Is a Potent Immunoadjuvant
Authors: Wei Feng , Yang De , Tewary Poonam , Li Yana , Li Sandra , Chen Xin , Howard O.M. Zack , Bustin Michael , Oppenheim Joost J.
Published: March 2023

Supplemental Table 1. Prediction of H-2-Kb MHC class I epitopes for human and mouse HMGN1
Supplementary Tables 1 - 4 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 88K, Supplementary Table I. Baseline characteristics of the HNSCC patients for microarray analysis. Supplementary Table II. Short Tandem Repeat Profile of the 2 HNSCC Cell Lines. Supplementary Table III. NOTCH Signaling Pathway Genes assigned in KEGG pathway database and shown on expression microarrays. Supplementary Table IV. Summary of the mRNA levels of NOTCH signaling pathway genes in the cohort of 44 HNSCC tumors and 25 normal mucosas measured by Affymetrix expression array.
Supplementary Materials from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

PDF file 121K, Supplementary Methods and Figure Legends
Supplementary Figure Legends from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: March 2023

PDF file, 83K.
Dataset S3 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

XLSX file 30K, Up-regulated genes assigned to GO:0008152 metabolic processing
Supplementary Figure 6 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 268K, Stainings of cytosolic DNA in Ara-C treated BC2 cells and Yac-1 cells in the presence of caffeine.
Supplementary Table 1 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: March 2023

PDF file - 22KB, Primer and shRNA sequences.
Supplementary Figure 6 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 157K, Proliferative Effect of CLPTM1L Depletion in Lung Tumor and Immortalized Bronchial Epithelial Cells.
Supplementary Table 1 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: March 2023

XLSX file - 398K, Lists of genes differentially regulated by DHT in cyclin D1+/+ mice, DHT regulated genes in cyclin D1-/- mice and genes differentially regulated by cyclin D1.
Supplementary Figure 1 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 94K, Relative CLPTM1L expression data from TCGA.
Supplementary Figure 4 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: March 2023

PDF file - 107K, Cyclin D1 expression signature is induced in prostatospheres and induction of Wnt.
Supplementary Table 1 from Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells
Authors: Satelli Arun , Mitra Abhisek , Cutrera Jeffry J. , Devarie Marcos , Xia Xueqing , Ingram Davis R. , Dibra Denada , Somaiah Neeta , Torres Keila E. , Ravi Vinod , Ludwig Joseph A. , Kleinerman Eugenie S. , Li Shulin
Published: March 2023

PDF file - 2927KB, Cell surface vimentin expression in different sarcoma cell lines.
Supplementary Figure 2 from Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells
Authors: Satelli Arun , Mitra Abhisek , Cutrera Jeffry J. , Devarie Marcos , Xia Xueqing , Ingram Davis R. , Dibra Denada , Somaiah Neeta , Torres Keila E. , Ravi Vinod , Ludwig Joseph A. , Kleinerman Eugenie S. , Li Shulin
Published: March 2023

PDF file - 89KB, In vivo detection of CTC from Mice and Dog models.
Supplementary Figures 1-3 from Extracellular RNA Liberates Tumor Necrosis Factor-α to Promote Tumor Cell Trafficking and Progression
Authors: Fischer Silvia , Gesierich Sabine , Griemert Barbara , Schänzer Anne , Acker Till , Augustin Hellmut G. , Olsson Anna-Karin , Preissner Klaus T.
Published: March 2023

PDF-180K, Supplementary Figure 1: Adhesion of tumor cells to endothelial cells by partly degraded eRNA. Supplementary Figure 2: eRNA-induced adhesion of tumor cells. Supplementary Figure 3: eRNA-mediated adhesion and transmigration of mouse fibrosarcoma cells.
Supplemental Methods and Reference from Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Authors: Qin Yan-Ru , Qiao Jun-Jing , Chan Tim Hon Man , Zhu Ying-Hui , Li Fang-Fang , Liu Haibo , Fei Jing , Li Yan , Guan Xin-Yuan , Chen Leilei
Published: March 2023

Description of additional methods and procedures used in the study. Also includes supplemental reference.
Supplementary Methods, Figure Legends, Tables 1 - 5 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 193K, Supplementary Table S1: Primers used to amplify the full-length mouse ICAT cDNA. Supplementary Table S2: Primers used to create the ICAT DQE mutant. Supplementary Table S3: Primers used for real-time quantitative PCR. Supplementary Table S4: siRNA oligonucleotides sequence. Supplementary Table S5: Endogenous level of ICAT, b-catenin, NEDD9 and Rac-GTP, cell morphology and migration speed in metastatic melanoma cell lines differ from non-metastatic cell lines.
Supplementary Figure 6 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: March 2023

PDF file - 126K, (A) IF images of Lu1205 cells transiently transfected with pcDNA3 (Mock), CMV::ICAT WT (ICAT WT), CMV::ICAT DQE (ICAT DQE) expression vectors and treated for 24 hr with NSC23766 (Rac inhibitor) or Y27632 (Rho/ROCK inhibitor). Cells were incubated with an anti-phalloidin-FITC antibody (green) and DAPI (blue). B, Percentage of Lu1205 round cells after transfection and inhibitor treatment. The values reported are means plus-minus SEM of three independent measures. Note that overexpression of ICAT WT in the presence of Y27632 (ROCK inhibitor) increases slightly, but significantly (p=0.03), the number of round cells when compared to Y27632-treated cells. ns = non significant.