bluuebunny/crossref_metadata_2025 huggingface dataset:
Técnica alternativa para fechamento de placas de microtécnica em exames de histocompatibilidade HLA
Authors: Paiva Sérgio Ré de , Paiva Tádia Maria Cordeiro de , Pontes Luciane Faria de Souza , Morínigo Fábio Cupertino
Published: October 2022

O Sistema HLA é composto por glicoproteínas integrais de membrana: as moléculas HLA A, B, C, DR, DO e DP. Entre as principais aplicações desse sistema encontram-se os estudos para os transplantes de medula óssea. Um importante avanço metodológico no estudo do sistema HLA surgiu com a descrição de um teste de microlinfocitotoxicidade: uma microtécnica empregada até os dias de hoje, na qual células portadoras dos HLA são utilizadas como alvo em reações de citotoxicidade desenvolvidas em microplacas específicas (placas Terasaki). A etapa final do método consiste na cobertura da placa com lamínula de vidro e leitura ao microscópio óptico de luz invertida. O presente trabalho apresenta uma técnica alternativa de fechamento da placa Terasaki que permite a leitura em microscópio óptico comum. Resume-se na colocação de um preparado tipo "gel" (Gelatina de Kaiser modificada) sobre a placa Terasaki ao término da metodologia usual, permitindo a inversão da mesma para leitura em microscópio óptico comum. O procedimento técnico de sorologia HLA é desenvolvido normalmente, e após coloração com eosina e fixação com formol neutro, a gelatina é dispensada na placa vagarosamente, devendo cobri-la homogeneamente. A preparação é deixada então à temperatura ambiente até que atinja o estado "gel". A leitura é feita em microscópio óptico comum, colocando-se a placa tampada com o fundo voltado para cima. Foram realizados 20 testes preliminares utilizando-se em paralelo a técnica convencional de fechamento e a técnica alternativa. A técnica mostrou-se econômica e de fácil execução, e a reprodutibilidade das leituras quando comparamos os dois métodos mostrou-se satisfatória. Nas placas em que se utilizou a Gelatina, novas leituras foram realizadas quinzenalmente durante 6 meses, e não se verificaram quaisquer alterações na morfologia celular nem no padrão de leitura.
Efecto bimodal de la ciclofosfamida en la terapia antineoplásica
Authors: Matar Pablo , Scharovsky O. Graciela
Published: October 2022

La Ciclofosfamida (Cy) es el agente alquilante más utilizado en el tratamento quimioterápico de diversas neoplasias humanas; habitualmente se la administra em combinación con otros citostáticos para lograr una mayor eficacia terapêutica. La mayoría de los protoeolos clínicos la emplean en dosis altas y suministrada en repetidas ocaciones a lo largo del tratamento antineoplásico, con Ias ya conocidas acciones colaterales, entre ellas la inmunodepresión. Sin embargo, en diferentes modelos experimentales en animales portadores de un tumor, la administración de uma dosis única y relativamente baja en un determinado momento de la respuesta inmune antitumoral, produce inmunopotenciación, a través de una inhibieión selectiva sobre los linfocitos T supresores. Posteriormente se demostró un efecto interesante y novedoso de éstas dosis bajas de Cy: su acción preferencial sobre células tumorales com fenotipo metastásico (probablemente debido a una inmunomodulación selectiva sobre dichas subpoblaciones celulares), ya que se observo una inhibieión total en la formación de Ias metástasis sin afectar el desarrollo dei tumor primário. Estos resultados senalan el efecto bimodal de la Cy sobre el sistema inmune dei huésped cuando se la utiliza en el tratamiento antineoplásico em diferentes dosis y esquemas de administración. La utilización de sustancias naturales denominadas “modificadores de la respuesta biológica”, ha derivado en lo que se conoce como cuarta modalidad terapêutica contra el cáncer. Se propone que la Cy sea considerada también dentro de ese contexto.
Câncer de esôfago: radioterapia pré-operatória
Authors: Silva Alcino Lázaro da , Nunes Tarcizo Afonso , Cunha Cassio Andrade , Carvalho Mário Gissoni de , Watty Arnaldo José , Silveira Filho Lourival da , Souza Antônio Francisco de , Martins Andréa Lúcia Oliveira Resende , Dourado Cândido , Martins Marcelo Mayrink
Published: October 2022

Um estudo realizado no Instituto Mineiro de Oncologia, no período de 1986 a 1992, envolveu 158 pacientes com câncer de esôfago. Destes, 47 (29,74%) foram submetidos a radioterapia (4400 cGy) e, um mês após, à esofagectomia. A histopatologia das peças ressecadas revelou a presença de tumor residual em 34 (72,34%) delas.
O auto-exame da boca como estratégia para a prevenção e o diagnóstico precoce do câncer bucal
Authors: Torres Inácio Andrade
Published: October 2022

O autor baseado em pesquisa bibliográfica e experiência profissional, aborda o câncer de boca enquanto problema nacional de saúde pública carente de discussão junto a comunidade e aponta o auto-exame como uma estratégia simples, eficaz e eficiente para a prevenção e o diagnóstico precoce dessa patologia.
Conhecimento de Enfermeiros sobre o Manejo da Dor Oncológica
Authors: Silva Beatriz Uchoa , Yoshioka Eliane Muta , Salvetti Marina de Góes
Published: October 2022

Introdução: A dor oncológica pode afetar o bem-estar físico, emocional e espiritual dos pacientes. O enfermeiro tem papel fundamental no controle desse sintoma, e a falta de conhecimento desse profissional pode ser uma barreira para o manejo adequado da dor. Objetivo: Avaliar o conhecimento de enfermeiros sobre manejo da dor oncológica e sua relação com variáveis sociodemográficas e de formação profissional. Método: Estudo descritivo transversal, realizado com enfermeiros de um Centro Oncológico no Estado de São Paulo. Os enfermeiros foram avaliados por meio de dois instrumentos para caracterização sociodemográfica/profissional e avaliação do conhecimento sobre manejo da dor no câncer, entre julho e setembro de 2019. Aplicaram-se os testes exato de Fisher e qui-quadrado de Pearson para avaliar a associação entre as variáveis. Resultados: Participaram do estudo 93 enfermeiros, predominantemente do sexo feminino (81,7%), católicos (36,6%), com média de seis anos de atuação profissional. Houve 50,5% de conhecimento inadequado sobre o manejo da dor oncológica e não se encontrou associação entre o conhecimento, as variáveis sociodemográficas e de formação profissional. Conclusão: Metade dos enfermeiros tem conhecimento inadequado sobre manejo da dor oncológica, e a falta de conhecimento não esteve associada às variáveis analisadas. Há necessidade de realizar intervenções educativas para melhorar o conhecimento dos enfermeiros e possivelmente aprimorar a assistência aos pacientes com dor oncológica.
Pemasaran Kampanye Sosial Yuk Nabung Saham dan Teori of Reasoned Action dalam Memperkirakan Niat Ber-investasi Saham (Studi Kasus pada new investor PT Reliance sekuritas Indonesia Tbk Cabang Tasikmalaya)
Authors: Budianto Apri , Badriatin Tine , Rinandiyana Lucky Radi
Published: October 2022

Penelitian ini dilakukan untuk mengetahui keefektifan Social Marketing Yuk Nabung Saham  dan Rational Action Theory dalam memprediksi niat berinvestasi saham investor baru pada Cabang PT. Reliance Securitas Indonesia Tbk Tasikmalaya. Metode yang dipakai yaitu metode deskriptif kualitatif. Hasil penelitian memperlihatkan bahwa kampanye social marketing Yuk Nabung Saham cukup efektif dalam memprediksi niat berinvestasi saham. Dengan kampanye pemasaran sosial Yuk Nabung Saham, kita berikan pemahaman baru kepada audiens tentang manfaat menyimpan saham. Teori tindakan rasional cukup efektif dalam memprediksi niat berinvestasi saham. Mengingat teori tindakan rasional yang merupakan salah satu cara untuk menyempurnakan penelitian ini, ternyata jika teori of reasoned action yang diterapkan oleh PT Reliance Securitas Indonesia Tbk Cabang Tasikmalaya lebih baik, maka harus dapat berniat untuk berinvestasi saham, meskipun persentasenya cukup rendah. Kampanye Pemasaran Sosial Yuk Nabung Saham dan Theory of Rational Action cukup efektif dalam memprediksi niat berinvestasi saham. Dengan kampanye pemasaran sosial Yuk Nabung Saham dan teori of Reasoned Action merupakan cara untuk meningkatkanniat berinvestasi penelitian ini membuktikan kampanye marketing social Yuk Nabung Saham yang lebih baik dan Teori of Reasoned Action yang dipimpin oleh PT Reliance Securitas Indonesia Tbk Cabang Tasikmalaya efektif dalam memprediksi niat untuk berinvestasi di saham, bahkan jika persentasenya cukup rendah..
Implementation of Personality Tests in the Learning Process in Era 4.0 Based on the Concept of Pumping HR Model for the world of Education in Indonesia
Authors: Ramly Amir Tengku
Published: October 2022

Understanding the character of learning is one of the important factors for success in learning and in the future. The era of 4.0 and the COVID-19 pandemic today has forced major changes in the teaching and learning system so that it is not disruptive. The learning process in the 4.0 era requires all-digital and effective breakthroughs. This condition is also supported by the COVID-19 pandemic which is predicted not to end soon. This study aims to (1) design a digital student character understanding test tool (2) develop students through a character approach to learning the Pumping HR Model concept, (3) develop teaching-learning techniques based on student character development through strengthening personality, competence and values. - spirituality values. The research method used is a qualitative study of literature and evaluation of the test equipment used for decades. The results of the study indicate that the implementation of personality tests (behavior and character) in the learning process in the 4.0 era greatly determines the effectiveness of the teaching and learning process. This effectiveness is strongly influenced by the implementation of three main components, namely (1) teacher integrity, (2) teacher competence, and (3) teacher personality in teaching, as part of the Pumping-HR Model framework.
Faktor Penentu Perilaku Hijau untuk Mengurangi Kantong Belanja Plastik
Authors: Humairoh Humairoh , Annas Mohammad
Published: October 2022

The environmental damage because by plastic waste is very stressful. Indonesia is the second country in the world to supply plastic waste into the ocean after China. one of the prevention efforts is to reduce using plastic shopping bags originating from the modern retail industry. This examines goals to analyze the impact of green promotion, green e-wom, and green consumer satisfaction factors on interest in the usage of zero plastic shopping bags and consumer behavior in reducing plastic shopping bags. The sample in this examination had 98 respondents who shop at modern retailers within the Tangerang area, Banten Province in assembly their each-day desires. The sampling approach used was purposive sampling. statistics collection used a survey approach with a questionnaire that was distributed thru the G-shape electronically. The statistics are processed with the assistance of the smart-PLS software program. The results display the positive effect of green marketing, green e-wom, green satisfaction, and interest in the use of zero plastic shopping bags on consumer behavior to reduce plastic shopping bags, both in part or simultaneously.
An Optimal Virtual Machine Placement Method in Cloud Computing Environment
Authors: Ramegowda Ashalatha
Published: October 2022

Cloud computing is formally known as an Internet-centered computing technique used for computing purposes in the cloud network. It must compute on a system where an application may simultaneously run on many connected computers. Cloud computing uses computing resources to achieve the efficiency of data centres using the virtualization concept in the cloud. The load balancers consistently allocate the workloads to all the virtual machines in the cloud to avoid an overload situation. The virtualization process implements the instances from the physical state machines to fully utilize servers. Then the dynamic data centres encompass a stochastic modelling approach for resource optimization for high performance in a cloud computing environment. This paper defines the virtualization process for obtaining energy productivity in cloud data centres. The algorithm proposed involves a stochastic modelling approach in cloud data centres for resource optimization. The load balancing method is applied in the cloud data centres to obtain the appropriate efficiency.
Scheduling Algorithms: Challenges Towards Smart Manufacturing
Authors: Degu Workneh Abebaw , Gmira Maha
Published: October 2022

Collecting, processing, analyzing, and driving knowledge from large-scale real-time data is now realized with the emergence of Artificial Intelligence (AI) and Deep Learning (DL). The breakthrough of Industry 4.0 lays a foundation for intelligent manufacturing. However, implementation challenges of scheduling algorithms in the context of smart manufacturing are not yet comprehensively studied. The purpose of this study is to show the scheduling No.s that need to be considered in the smart manufacturing paradigm. To attain this objective, the literature review is conducted in five stages using publish or perish tools from different sources such as Scopus, Pubmed, Crossref, and Google Scholar. As a result, the first contribution of this study is a critical analysis of existing production scheduling algorithms' characteristics and limitations from the viewpoint of smart manufacturing. The other contribution is to suggest the best strategies for selecting scheduling algorithms in a real-world scenario.
ОСОБЛИВОСТІ ПРОФЕСІЙНОГО СТАНОВЛЕННЯ СТУДЕНТІВ-ПСИХОЛОГІВ
Authors: Осьодло В. , Сердюк Л. , Курбатова А.
Published: October 2022

У статті здійснено аналіз психологічних чинників професійного становлення студентів ЗВО. Виявлено особливості мотивів вибору професії та професійної спрямованості студентів, здійснено аналіз мотиваційно-смислових та особистісних характеристик їх професійного становлення. Визначено, що психологічний зміст професійного становлення студентів полягає в знаходженні особистісних основ професійного вибору.
АСПЕКТИ ПРОЯВІВ НЕГАТИВНИХ ПСИХОЛОГІЧНИХ РЕАКЦІЙ НА РЕАЛІЇ ВІЙНИ В УКРАЇНСЬКОМУ СУСПІЛЬСТВІ
Authors: Скрипкін О.
Published: October 2022

В статті викладено результати досліджень проявів характерних негативних психологічних реакцій, які виникли в українському суспільстві з початком широкомасштабної військової агресії Російської Федерації проти України. Описано орієнтовний механізм їх формування та характер відображення в міжособистісних (міжгрупових) комунікаціях на воєнному тлі.
ІНДИВІДУАЛЬНО-ПСИХОЛОГІЧНІ ОСОБЛИВОСТІ СУБ`ЄКТІВ, ЯКІ ДЕМОНСТРУЮТЬ РІЗНІ ВИДИ ОСОБИСТІСНОГО ВИБОРУ
Authors: Якимчук Б.
Published: October 2022

У статті подано результати емпіричного дослідження, яке ставило на меті виокремити два основні види особистісного вибору – активний та реактивний (на основі суб'єктивного параметра – підстав для аргументації власного вибору), а також основні індивідуально-психологічні особливості суб'єктів, що характеризуються різними видами вибору. Зазначається, що суб'єкти, які демонструють різні види особистісного вибору, розрізняються за такими індивідуально-психологічними передумовами, як життєстійкість, толерантність до невизначеності, усвідомленість життя, параметри суб'єктивної якості вибору, тип каузальної орієнтації, ставлення до особистого майбутнього, тривалість тимчасової перспективи, особливості самоорганізації діяльності та самоефективності.
ІНДИВІДУАЛЬНО-ПСИХОЛОГІЧНІ ПЕРЕДУМОВИ ТА ВИДИ ОСОБИСТІСНОГО ВИБОРУ
Authors: Якимчук І.
Published: October 2022

У статті подано результати виокремлення видів особистісного вибору за суб'єктивними та об'єктивними параметрами та вивчення індивідуально-психологічних особливостей суб'єктів, що демонструють різні види особистісного вибору. При одночасному розгляді суб'єктивних та об'єктивних параметрів можна виокремити три види особистісного вибору: реактивний вибір, активний вибір незмінності та активний вибір невідомості. Можливість здійснення вибору того чи іншого виду забезпечується наявністю індивідуально-психологічних передумов, які є низкою диспозицій, різний рівень виразності яких створює більш менш сприятливі умови для здійснення вибору різного виду. Різні види особистісного вибору відображають різні способи осмислення, аргументації, підготовки, а також різні механізми його здійснення.
ГЕНДЕРНІ ОСОБЛИВОСТІ МІЖОСОБИСТІСНОЇ ВЗАЄМОДІЇ СТУДЕНТІВ-ПСИХОЛОГІВ ЯК ПЕРЕДУМОВА ФОРМУВАННЯ ГОТОВНОСТІ ДО ПРОФЕСІЙНОЇ ДІЯЛЬНОСТІ
Authors: Комар Т.
Published: October 2022

Формування готовності до професійної діяльності психолога розглядається у взаємозв’язку із гендерною самоідентифікацією, що здійснюється в умовах міжособистісної взаємодії студентства, яка спрямована на становлення певного типу поведінки в різноманітних ситуаціях спілкування, на безконфліктну взаємодію, а саме на шляхи поведінки у ній задля досягнення конструктивного результату у соціальній та професійній діяльності відповідно до схильностей особистості, вимог до сучасного професіонала.
ПСИХОЛОГІЧНІ ОСОБЛИВОСТІ ОСОБИСТІСНИХ ЗМІН ПЕРЕСЕЛЕНЦІВ В УМОВАХ ІНШОЇ КРАЇНИ (НА ПРИКЛАДІ НОРВЕГІЇ)
Authors: Максименко Ю. , Морозова-Йоханнессен О.
Published: October 2022

У статті розкрито особливості особистісних змін переселенців з України внаслідок російського вторгнення під час їх перебування у Норвегії. Дослідженням охоплено 102 особи віком від 18 до 75 років, серед яких студенти, молодь, матері з дітьми, пенсіонери. Емпірично встановлено наявність у респондентів низки психологічних особливостей що торкаються емпатичних процесів, які розглядались в вигляді широкого кола переживань іншої людини.
Documentosophy as the philosophical conceptualization of document entity
Authors: Stolyarov Yu. N.
Published: October 2022

The author continues to substantiate the goal set by Arkady Sokolov to conceptualize the document entity.

   As the initial point, he took Sokolov’s definition of documentosophy as the segment of sociocultural space to build, transfer, preserve and user meaningful communication messages referred to as documents. Sokolov also refers to the sphere of sociocultural production where the documents emerge, circulate and are preserved, as the documentosphere. The author argues that the adequate definition of the document is possible in its dialectic object-subject perception according to the international definition: the document is an object or recorded information provided that in the given documentation process (rather than generally!) it can be considered (by a subject) as a discrete whole. This results in the need to specify restrictions and to formulate narrower definition of the document specifically for each individual documentation process. The fundamental provision of relativity, conformity and conventionality of the concept “document” is explained; the author criticizes the mediaology claiming to replace documentive concepts with medialogical structures. In fact, the subject of documentology coincides with that of mediaology. However, firstly, each science has its own term, and, secondly, these are just their approaches that differ, i. e. the ontological approach is applied in documentology, and the communicative one in mediaology. The mediaology has been diligently though unreasonably avoiding the concepts of “document” and “information”. Thirdly, as opposed to documentology, the mediaology has been still unable to propose any brand-new and valuable insight into the document phenomenon.
Blockchain analysis of the Bitcoin market. (Part 1) (The article published both in original and Russian translation)
Authors: Makarov I. , Schoar A.
Published: October 2022

This article presents a detailed analysis of the Bitcoin network (Bitcoin) and its main participants, carried out by authoritative experts - Igor Makarov from the London School of Economics and Antoinette Shoart from the Massachusetts Institute of Technology - on behalf of the National Bureau of Economic Research (NBER) - a private organization in the United States. The Bitcoin network is defined as a new database that includes a large number of public and proprietary sources for linking bitcoin addresses to real objects and an extensive set of algorithms for extracting information about the behavior of major market participants. The analysis of the Bitcoin ecosystem consisted of three main stages. First, the volume of transactions and the network structure of the main participants in the blockchain are analyzed. Secondly, the concentration and regional composition of miners who carry out verification (verification) and ensure the integrity of the blockchain registry (ledger, ledger) are documented. Thirdly, the concentration of ownership of the largest holders of bitcoins is considered.
Theoretical principles and practical approaches to the relations regulation between the participants of the meat supply chain
Authors: Kopytets N. , Voloshyn V.
Published: October 2022

The article is studies theoretical principles and practical approaches to the settlement of relations between the food chain participants in the meat market. The issues of formation and transformation of food chains are currently one of the most discussed and studied by foreign and domestic scientists. It is substantiated that the share of direct producers of beef and pork has a negative dynamics of reduction and ﬂuctuates within 30-40% in the fnal price formation. The share of producers in the retail price of poultry meat is much higher (47.1-59.5%) due to vertical integration and a closed production cycle. It is proved that the inconsistency of economic relations between the participants of the "production - processing - trade - the meat market consumer" chain aﬀects both the supply of meat processing plants with raw materials and the formation of prices that would satisfy all the participants and results in unsatisfactory price situation for meat. Generalization of theoretical, methodological and practical principles of the "production-processing-trade-consumption" food chain, analysis and evaluation of the role of each of the links and studying the international experience gives grounds for identifying a number of areas in regulation of the relations and predetermine the increase the producer share in the chain through concluding fair and eﬀective agreements between meat market participants; creation of agricultural service cooperatives and other associations of producers; establishment and running a network of wholesale markets for agricultural products; support for the creation and development of short supply chains; development of innovative logistics approaches and methods based on modern digital technologies. It is established that the relations between the participants of the chain "production-processing-trademeat market consumption" should be based on the principles of trust, justice, mutual respect, corporate social responsibility. It is substantiated that changes in consumer demands for food, including meat, increased competition, changes in government regulation, technological advances, increased emphasis on efficiency and sustainability, food safety aﬀect changes in business and competitiveness strategies, which ultimately cause transformations in food chains in the form of new and innovative logistics approaches and methods.
Key words: meat market, food chain, price, relationship settlement, innovative logistics approaches.
The tools of convergence theory in economic science and practice of regional policy in Ukraine
Authors: Shibaeva N. , Storozhenko I. , Baban T.
Published: October 2022

Modern economic approaches to understanding the impact of disparities on the economic development of the regions of Ukraine are analyzed. The study was conducted using elements of convergence theory. The study was based on gross regional product (GRP) per capita and the Gini coefcient by region for the period 2004 - 2019. Absolute convergence was chosen as the methodological basis. Sigma and beta convergence methods were used to determine the trend of convergence of economic indicators between regions. The dynamics of inequality of the Ukraine regions development in the period from 2004 to 2019 was tested: the years in which regional policy was conducted in the absence of strategic planning (2004 - 2005) and with its use (2006-2019). It is established that sigma convergence processes were not observed during the analyzed period, as evidenced by the upward trend in the values of the calculated coefcient of variation and Gini coefcient. The reliability of the obtained results is confrmed by data obtained from other sources of information (Regional Human Development Index, data from the Ministry of Development of Communities and Territories of Ukraine). The calculation of the Gini forecast coefcient until 2027 did not confrm the decrease in the diﬀerentiation of the regions of Ukraine in the forecast period. The calculations showed that the average region needs 14.6 years to cover half of the distance that separates it from the steady state, which corresponds to a convergence rate of 3.37% per year. It was found that the current regional policy identifed trends in the study and developed forecasts are not taken into account, which complicates the achievement of the goal set in the State Strategy for Regional Development until 2027. It was found that the results do not allow conclusions about the eﬀectiveness of regional policy. Therefore, further research is needed, in particular the identifcation and calculation of variables that reﬂect the impact of regional policy on regional imbalances. It is also advisable to take into account and check the presence of "club" convergence, i.e. by groups of regions within the country.
Key words: convergence, regions, regional policy, development strategy, forecasting, level of development, economic growth, efficiency.
Conceptual bases of agricultural enterprises development
Authors: Lanchenko Y.
Published: October 2022

The subject of scientifc research is the scientifc and practical principles of development of various types of agricultural enterprises in Ukraine. The purpose of the article is to substantiate the conceptual directions of production in small, medium and large agricultural enterprises in the war and postwar period. The data of the State Statistics Service of Ukraine, regulatory acts of Ukraine and the scientifc research (abstract-logical, system approach, monographic, statistical-economic method) were used. Based on the retrospective analysis of agricultural enterprises production efciency, the key areas of economic activity of large, medium and small agricultural enterprises are identifed. In the conditions of wartime and the further postwar period, when a signifcant decline in investment activity is expected, agricultural production will be oriented towards more labor-intensive and less capital-intensive types of agribusiness, in particular in small and medium agricultural enterprises. In agricultural enterprises there is a different share of working capital in the total value of assets. In small enterprises, the capital structure is dominated by working capital, while in large – fxed capital and capital security is 3-4 times higher than in other types of enterprises in the branch. Based on this, in a state of war and the risk of capital investment in the industry, the most economically advantageous is the situation in small and medium enterprises, where the best rates of return on investment and rates of return. It is proved that for large agricultural enterprises it is necessary to determine the economic vectors of their development in the short and medium term. In particular, to diversify agribusiness and combine the development of crop and livestock production, to diversify sales channels to the external food market, and to focus on the domestic consumer market. Also, these companies need to pay attention to the production of biofuels, other energy resources and more. Based on the analysis of capital investment in various types of agricultural enterprises, the directions of investment in agricultural machinery and equipment are substantiated (they can be moved quickly in case of the military front approach). Such investment and reproduction processes can be traced in small and medium enterprises, in contrast to large enterprises, which have invested a lot in the construction of production and logistics facilities. Small, medium and large forms of entrepreneurship in agribusiness should take their place in the economy of rural areas. The study has generalized the conceptual directions – strategic landmarks of social and economic development of various types of agricultural enterprises for the future period are.
Key words: entrepreneurship, agricultural enterprise, farming, food security, employment, economic efciency, capital investments.
Fish biodiversity and livelihood of fishermen at an Oxbow lake of South-West Bangladesh
Authors: Jamil - , Sharif BM Newaz , Abit Lirong Yu , Miah Md Idris , Shahjahan Md
Published: October 2022

The present study was conducted to know the biodiversity status and assess the existing livelihood conditions of the fishers of Habullah Baor at Bagherpara upazila, Jashore district from November 2017 to April 2018. Sixty fishermen were randomly selected for collecting data through a semi structured questionnaire. The current study discovered that there were 11 different fish species from six orders and seven families in the Habullah baor. All of the sampled fishermen were Hindu. About 25% of the fishermen was young aged, majority was middle aged and 25% was old aged group. A total of 75% of the fishermen had nuclear family and 25% families lived in joint family. Among the fishermen 85% had a few decimal of cultivable land and 15% were truly landless. Annual income of the respondents varied from 30,000 to 70,000 BDT with an average of 42,833 BDT. All fishers had access to drinking water from tube wells. Most of the fishers lived in katcha houses. About 15% of the fishers enjoyed electricity facilities in their home. Among the fishermen investigated, majority had earthen latrine, 20% used tin shed latrine, 8% used concrete latrine and a few of them 10% had no latrine. There were no modern medical facilities in the villages. The respondents had no alternate income sources during the dry season and at the time of ban period. The fishers as a whole are leading measurable life due to great financial hardship. Proper conservation and management measures can be taken to enhance the availability of fish fauna in Habullah baor, so that, the fishermen can harvest ample fish on sustainable basis.
Asian J. Med. Biol. Res. 2022, 8 (3), 165-180
Gaya Kepemimpinan Otokratis dan Stres Kerja dalam Mempengaruhi Turnover Intention
Authors: Ayuningtyas Eka Avianti , Fadilah Dewi Oktavianti , Maskuri Muh. Ali , Marliah Siti
Published: October 2022

Penelitian ini dilakukan di PT. Bersama Lemindo Abadi dengan tujuan yaitu mengetahui pengaruh gaya kepemimpinan otokratis dan stres kerja terhadap turnover intention. Data penelitian diperoleh dari sampel penelitian yaitu 74 karyawan menggunakan sampel jenuh dengan jalan mengisi kuesioner penelitian. Analisis dilakukan secara kuantitatif yaitu analisis deskriptif, uji instrumen, persyaratan analisis, model dan hipotesis melalui regresi linier ganda pada taraf uji 5%. Penelitian menunjukkan bahwa gaya kepemimpinan otokratis positif dalam mempengaruhi turnover intention. Stres Kerja positif dalam mempengruhi turnover intention.This research was conducted at PT. Together with Lemindo Abadi with the aim of knowing the influence of autocratic leadership style and work stress on turnover intention. The research data was obtained from the study sample, namely 74 employees using saturated samples by filling out the research questionnaire. The analysis was carried out quantitatively, namely descriptive analysis, instrument tests, analysis requirements, models and hypotheses through double linear regression at a test level of 5%. Research shows that autocratic leadership styles are positive in influencing turnover intentions. Work Stress is positive in affecting turnover intention.
Kualitas Pemasaran Digital, Produk dan Distribusi dalam Upaya Mewujudkan Kepuasan Pelanggan
Authors: Asari Muhamad , Mahmudah Siti
Published: October 2022

Penelitian ini berupaya memperoleh gambaran kualitas pemasaran digital, produk dan distribusi dalam mewujudkan kepuasan pelanggan.  Populasi yang dipilih adalah terbatas pada pelanggan produk madu Kp. Cioray Klapanunggal Desa Leuwikaret Kabupaten Bogor Binaan STIE IPWIJA. Kemudian penarikan sampel sebanyak 100 responden dari  anggota populasi dilakukan secara insidental. Data kuantitatif diperoleh dari persepsi pelanggan melalui pengisian kuesioner yang dianalisis dengan regresi linier berganda. Hasil penelitian menunjukkan kualitas pemasaran digital, produk dan distribusi positif mempengaruhi kepuasan pelanggan.This research seeks to obtain an overview of the quality of digital marketing, products and distribution in realizing customer satisfaction.  The population chosen is limited to customers of honey products Kp. Cioray Klapanunggal Leuwikaret Village, Bogor Regency, Assisted by STIE IPWIJA. The sampling of 100 respondents from members of the population was carried out incidentally. Quantitative data are obtained from customer perception through the filling out of questionnaires analyzed by multiple linear regression. The results showed that the quality of digital marketing, products and distribution positively affected customer satisfaction.
Using mathematics to known how to teach climate change to pre-service teachers: Is knowledge enough?
Authors: Fuertes-Prieto Miguel Ángel , Ferrari-Lagos Enzo , Andrés-Sánchez Santiago , Corrochano Diego , Ballegeer Anne-Marie , Delgado-Martín Maria Laura , Herrero-Teijón Pablo , Ruiz Camilo
Published: October 2022

Climate Change is one of the greatest challenges for humanity and education plays a fundamental role in raising awareness in society about the importance and need to take adaptation and mitigation measures. Climate Change can be treated from the point of view of education as a competence formed by three dimensions: knowledge, skills and attitudes. In this study we have looked to establish how these three parts are related among them, and if an increase in the part of knowledge also implies a change in skills and/or attitudes. To this purpose, 84 future pre-service teachers have received training focused only on the knowledge part about climate change: what it is and what its causes are. Through a survey carried out before and after the training, the value of each of the parts that make up the competition has been measured. The results show that a training focused on knowledge also improves the attitudinal part, but not the skills part. Therefore, if you want to achieve complete climate competence, it is not enough to teach knowledge, but it is also necessary to pay attention to skills during the formation. These results should be considered when designing the teaching on Climate Change, in order to optimize the resources and time available.
Exploring Alignment between the Lesotho Secondary DS teachers' Pedagogy and Work Related Skills
Authors: Lekhanya Ngoanannete , Raselimo Mohaeka Gabriel
Published: October 2022

This paper explores alignment between Lesotho secondary Development Studies (DS) teachers’ pedagogical practices and corporate world skills. The study complimentarily employed three research questions in determining approaches teachers employ in DS classrooms, corporate world skills such approaches are intended to promote and availability of necessary resources to support their promotion. Data was generated from six schools using semi-structured interviews and classroom observations. The findings reflected no interface between interviews generated data and observations on teachers’ practices. Despite being highly qualified and experienced, DS teachers in Lesotho are inclined to rote learning and therefore fail to deliver appropriate DS pedagogy for attainment of the desired work competencies. The practiced subject pedagogy is inconsistent with its teaching philosophy, the theoretical framework and complementing theory in this study. The findings suggested that there is need to revise teacher training programmes while also introducing continuous professional development (CPD) to change DS teachers’ pedagogical practices.
Avaliação de cultivares de soja para a região do ecótono cerrado pantanal
Authors: Prochnow Leticia Carolina de Oliveira , Guedes Pedro Henrique , Santana Dthenifer Cordeiro , Torres Francisco Eduardo
Published: October 2022

A soja possui grande importância social e afeta de maneira significativa a economia do Brasil e do mundo. Por ser cultivada em diversas regiões é importante desenvolver cultivares que adaptam aos distintos microclimas de cada local. Por essa perspectiva é essencial avaliar como as cultivares se comportam em uma dada região antes de implantar ela como lavoura. O objetivo deste trabalho foi avaliar caracteres agronômicos em diferentes cultivares de soja implementadas no ecótono Cerrado Pantanal. O experimento foi conduzido na safra 2019/2020 no setor de Fitotecnia da Universidade Estadual de Mato Grosso do Sul - Unidade Universitária de Aquidauana (UEMS/UUA), no município de Aquidauana-MS. O delineamento experimental foi de blocos ao acaso, com vinte e três tratamentos e quatro repetições, avaliando 23 cultivares. Feita a coleta e tabulação dos dados, eles foram submetidos as análises multivariadas: Componentes principais e análise de cluster. A cultivar C11 se destacou com a variável AP, fator indireto contribuinte na produtividade assim como AIV, que houve destaque para as cultivares C13, C16 e C17. A cultivar C7 alcançou a maior média para a MCG.
Evaluation of surgery indication of cold knife conization and anatomopathological reports in patients with cervical squamous intraepithelial lesion or cervical cancer
Authors: Moraes Bárbara Bomfim Muniz , Uyeda Maria Gabriela Baumgarten Kuster , Mattos Patrícia Napoli Belfort , Almeida Bruna Cristine de , Campos Madalena Leonor Pereira , Focchi Gustavo Rubino de Azevedo , Speck Neila Maria Góis , Tso Fernanda Kesselring
Published: October 2022

O objetivo desse trabalho fundamentou-se em avaliar a concordância entre a indicação cirúrgica de conização clássica por citologia cervical (CC), biópsia ou excisão da zona de transformação (EZT), e o resultado anatomopatológico final das pacientes submetidas ao procedimento devido a lesões precursoras ou câncer do colo do útero. Além disso, visou observar a presença de lesão residual após EZT com diagnóstico histológico de  carcinoma espinocelular (CEC) microinvasivo e margens comprometidas por lesão intraepitelial de alto grau (LIEAG). Para tal, realizou-se estudo retrospectivo envolvendo 82 mulheres com lesões intraepiteliais cervicais ou câncer com idade entre 28 e 71 anos. Estas foram submetidas a citologia cervicovaginal, biópsia de colo ou EZT entre janeiro de 2014 e janeiro de 2020 e tiveram a conização clássica indicada de acordo com os resultados dos procedimentos diagnósticos. A indicação cirúrgica foi a citologia em 30.5% dos casos; em 12.2%, foi devido à biópsia cervical, e em 24.4%, devido à citologia confirmada pela biópsia. Além disso, 32.9% das pacientes tiveram a cirurgia realizada devido a margens comprometidas após EZT. Foi encontrada concordância em 57.3% das indicações e 42.7% não apresentaram concordância. Observou-se lesão residual em 55.6% de todas as pacientes submetidas a EZT, mas no grupo de CEC microinvasivo, houve taxa de 60% de ausência de lesão residual na peça cirúrgica da conização. Portanto, isso indica que a EZT parece ser tratamento eficaz para o CEC microinvasivo do colo do útero, e uma cirurgia complementar parece não ser necessária na presença de margens comprometidas por LIEAG.
Justiça ambiental enquanto consciência social em tempos de negacionismo
Authors: Rosa Gisele da Silva Rezende da , Campos Juliano Bitencourt , Silva Alex Sander da , Zocche Jairo José , Vieira Reginaldo de Souza
Published: October 2022

Nesse ensaio critico-reflexivo busca-se discutir o papel da justiça ambiental enquanto consciência social, articulando a discussão com a necessidade de se pensar os desafios em tempos de negacionismo. Uma questão que se coloca aqui é: de que forma a consciência social pode interferir na construção da justiça ambiental, a partir de um contexto social local, com influência global em tempos de negacionismo? O objetivo central do presente texto diz respeito a enfrentar o debate contemporâneo em torno dos conceitos de justiça ambiental e consciência social, de modo a intervir de forma qualificada para que o atual quadro seja modificado. A pesquisa foi desenvolvida utilizando o método  dialético, por intermédio da abordagem qualitativa, com técnicas de pesquisa documental- trazendo aspecto legal e bibliográfico. Entre os resultados que podem ser apontados estão a identificação de relações humanas estabelecidas que, por vezes, têm causado prejuízo as questões ambientais decorrentes de um contexto desafiador e do modus operandi como forma de Resistencia critica que se contrapõe a esse negacionismo.
Avaliação da prevalência infecciosa e sensibilidade aos antimicrobianos em otite externa de cães em Mineiros região Centro-Oeste do Brasil
Authors: Ribeiro Debora da Silva Freitas , Supptitz Jederson da Silva , Ribeiro Rodrigo Martins
Published: October 2022

A otite externa é uma patologia inflamatória muito comum em pequenos animais, sendo uma das principais afecções que motivam os tutores de cães e gatos a procurarem atendimento veterinário. É uma doença que apresenta diversos fatores desencadeadores e tem os agentes infecciosos como as principais causas. Os sinais clínicos observados nos animais são eritema, dor, prurido, secreção otológica, odor fétido e meneios de cabeça. O diagnóstico se baseia na anamnese, exame clínico do animal, com auxílio do otoscópio, considerando os achados epidemiológicos, resultados dos exames citológicos, culturas e testes de sensibilidade antimicrobiana. O tratamento é firmado na prévia limpeza do conduto auditivo aliado à terapia antimicrobiana tópica e ou sistêmica. O objetivo deste trabalho é estabelecer a microbiota bacteriana, fúngica e parasitária, presentes nas otites externas infecciosas de cães e gatos atendidos na clínica veterinária, bem como identificar os antimicrobianos com maior eficácia in vitro e obter dados epidemiológicos tais como raça, sexo e faixa etária predominante sobre essa afecção na região de Mineiros/GO.
A eficácia da Aloe vera no processo cicatricial da Lesão Por Pressão: um estudo de caso
Authors: Ribeiro Jhenyfer Alves , Rocha Kallyna de Oliveira Sousa , Dias Pinheiro Julliana , Souza Nathalya Jacob Rodrigues
Published: October 2022

O presente estudo teve como objetivo relatar o processo cicatricial de uma LPP tratada com gel à base de Aloe vera. Trata-se de um estudo de caso descritivo, com abordagem qualitativa, desenvolvido em um hospital público na região Sul do Estado do Tocantins, com um paciente hospitalizado que apresentava LPP estágio 4 na região sacral. Realizou-se a anamnese, exame físico e acompanhamento do processo cicatricial da lesão, utilizando o gel à base de Aloe vera a 0,5%. O processo de cicatrização foi acompanhado através do registro fotográfico nos dias 0, 30, 75 e 150 de tratamento. Os resultados obtidos foram satisfatórios, evidenciando que a Aloe vera tem grande ação no processo de reparação, cicatrização e hidratação tecidual. Conclui-se que uso da Aloe vera, no tratamento de lesões por pressão, pode trazer benefícios, devido ao seu grande potencial cicatrizante, facilitando a cura e reconstituição dessas lesões.
Optimizing preparation of the fenell (foeniculum vulgare L.) extracts by using ultrassound - methodology in accordance with the principles of green chemistry
Authors: Leão Enzo Mendes , Costa Clara Cardoso , Campos Catharine de Sousa Batista , Silva Bárbara Ferreira Lemos da , Machado Ana Maria de Resende , Lucas Esther Maria Ferreira
Published: October 2022

Fennel (foeniculun vulgare L.) is a vegetal species that presents bioactive monoterpenes. These compounds are lipophilic substances almost insoluble in water. The best conditions to extract these substances, employs organic solvents or heating process. With the aim to developing new extractive methods in which the green chemical principles cam be applied, this work was performed. The effect of the use of ultrasound during the preparation of fennel extracts by water infusion and by ethyl acetate maceration methods was verified. The ethyl acetate extracts, and the organic portion of the aqueous extracts were analyzed by gas chromatography coupled to mass spectrometry. The ethyl acetate extraction, without the use of ultrasound leads only to the extraction of two metabolites (fenchone and anethole), the maceration performed by using ultrasound by 5 and 10 minutes, promoted the extraction of seven metabolites (a-pinene, L-fenchone, estragole, anethole, β-caryophyllene, a-cadenol, and geranylgeraniol), while the use of ultrasound in times upper than 10 minutes leas to extracts with 4 metabolites (a-pinene, L-fenchone, estragole and limonene). The aqueous extracts submitted or not to the use of ultrasound led to the extraction of the same and five metabolites (D-limonene, L-fenchone, estragole, and anethole).
Idoso hospitalizado: Enfoque na humanização da assistência em enfermagem
Authors: Silva Francisca de Souza Abreu , Silva Francisco Ronner Andrade da , Salgado Paula Regina Rodrigues , Caetano Bruno Rolim Félix , Souza Bruna Caroline Ruthes de , Pedroza Ariadne Pereira , Carvalho Enyedja Kerlly Martins de Araújo , Carvalho José Ribamar Marques de , Araújo Andrea Mendes , Lavôr Maria Jaqueline Moura
Published: October 2022

Introdução: O envelhecimento populacional compreende um fenômeno em crescimento, tornando-se um desafio para todos e, em especial, para os serviços de saúde, pois impulsiona também o aumento da prevalência das doenças crônicas degenerativas e, consequentemente, a hospitalização dos idosos Objetivo: Identificar as práticas assistenciais de enfermagem voltadas à humanização direcionada ao atendimento do idoso hospitalizado. Método: Revisão Integrativa, uma Prática Baseada em Evidências (PBE), em que foram identificados 93 artigos extraídos das bases de dados indexadas na Biblioteca Virtual em Saúde (BVS): Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (SCIELO), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Portal CAPES) e Sistema Online de Busca e Análise de Literatura Médica (MEDLINE). Foram selecionados mediante a leitura analítica 10 artigos, considerando como critério de inclusão os artigos completos disponíveis na íntegra, no idioma português e publicados entre os anos de 2017 e 2021, com discussões relevantes ao idoso hospitalizado. Como critério de exclusão, artigos duplicados, fora do tema e do período definido para essa pesquisa. Resultados: Mediante a leitura dos artigos que compõem o corpus desta pesquisa, observa-se que, apesar de ser uma prática conhecida e desenvolvida por muitos, ainda se faz necessária a realização de novos estudos que possibilitem abordagens a partir das opiniões dos próprios idosos, não apenas dos profissionais, visto que essa é uma população que tende a crescer ainda mais e, sobretudo, porque a humanização durante o atendimento é uma prática preconizada em lei.