bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatial patterns and influencing factors of financial agglomeration in Guangdong-Hong Kong-Macao Greater Bay Area
Authors: Wei Yujun , Wang Mengbin , Wei Xiaokun , Yuan Fan , Fan Jie , Ba Shusong
Published: August 2024

The Guangdong-Hong Kong-Macao Greater Bay Area (GBA) represents a significant economic zone with a diverse financial landscape. Understanding the spatial distribution of financial resources within this area is crucial for promoting balanced economic growth and financial development. This study investigates the spatial patterns of financial agglomeration in the GBA, identifying key influencing factors and assessing their impact on the region’s financial landscape. We employ the entropy value method to evaluate financial agglomeration levels across the GBA’s cities. Additionally, we use spatial econometric techniques to analyze the spatial correlations and the Geo-Detector model to determine the primary factors influencing financial agglomeration. The analysis reveals an overall increase in financial agglomeration, with significant disparities among cities. Key factors driving this agglomeration include transportation infrastructure, overseas trade, foreign direct investment (FDI), and technological advancements. Hong Kong and Shenzhen display notable unevenness in the distribution of financial industries. The interplay between finance, technology, and industrial sectors suggests considerable development potential. Understanding and optimizing the spatial distribution of financial resources is essential for fostering high-quality financial development and sustainable economic growth in the GBA. This study provides insights that can inform policy decisions aimed at enhancing financial integration and cooperation within the region.
Excitatory to inhibitory synaptic ratios are unchanged at presymptomatic stages in multiple models of ALS
Authors: Bonthron Calum , Burley Sarah , Broadhead Matthew J. , Metodieva Vanya , Grant Seth G. N. , Chandran Siddharthan , Miles Gareth B.
Published: August 2024

Hyperexcitability of motor neurons and spinal cord motor circuitry has been widely reported in the early stages of Amyotrophic Lateral Sclerosis (ALS). Changes in the relative amount of excitatory to inhibitory inputs onto a neuron (E:I synaptic ratio), possibly through a developmental shift in synapse formation in favour of excitatory transmission, could underlie pathological hyperexcitability. Given that astrocytes play a major role in early synaptogenesis and are implicated in ALS pathogenesis, their potential contribution to disease mechanisms involving synaptic imbalances and subsequent hyperexcitability is also of great interest. In order to assess E:I ratios in ALS, we utilised a novel primary spinal neuron / astrocyte co-culture system, derived from neonatal mice, in which synapses are formed in vitro. Using multiple ALS mouse models we found that no combination of astrocyte or neuron genotype produced alterations in E:I synaptic ratios assessed using pre- and post-synaptic anatomical markers. Similarly, we observed that ephrin-B1, a major contact-dependent astrocytic synaptogenic protein, was not differentially expressed by ALS primary astrocytes. Further to this, analysis of E:I ratios across the entire grey matter of the lumbar spinal cord in young (post-natal day 16–19) ALS mice revealed no differences versus controls. Finally, analysis in co-cultures of human iPSC-derived motor neurons and astrocytes harbouring the pathogenic C9orf72 hexanucleotide repeat expansion showed no evidence of a bias toward excitatory versus inhibitory synapse formation. We therefore conclude, utilising multiple ALS models, that we do not observe significant changes in the relative abundance of excitatory versus inhibitory synapses as would be expected if imbalances in synaptic inputs contribute to early hyperexcitability.
Improving semi-arid agroecosystem services with cover crop mixes
Authors: Moore Elizabeth A. , Norton Urszula
Published: August 2024

Winter wheat (Triticum aestivum, L.) production in the semi-arid US Northern High Plains (NHP) is challenged by frequent droughts and water-limited, low fertility soils. Composted cattle manure (compost) and cover crops (CC) are known to provide agroecosystem services such as improved soil health, and in the CC case, increased plant diversity, and competition with weedy species. The main concern of planting CC in winter wheat fallow rotation in regions that are more productive than the NHP, however, is the soil moisture depletion. It is unknown however, whether addition of CC to compost-amended soils in the NHP will improve soil properties and agroecosystem health without compromising already low soil water content. The main objective of this study was to assess the effects of four CC treatments amended with compost (45 Mg ha-1) or inorganic fertilizer (IF) (.09 Mg ha-1 mono-ammonium phosphate, 11-52-0 and 1.2 Mg ha-1ammonium sulfate, 21-0-0) on the presence of weeds, soil and plant total carbon (C), nitrogen (N), and biological dinitrogen (N2) fixation (BNF). Mycorrhizal Mix (MM), Nitrogen Fixer Mix (NF), Soil Building Mix (SB), a monoculture of phacelia (Phacelia tanacetifolia Benth L.) (PH), and a no CC control (no CC) were grown in native soil kept at 7% soil moisture in a greenhouse for a period of nine weeks. When amended with compost, MM was the most beneficial (48 g m-2 BNF and 1.7% soil C increase). SB had the highest germination, aboveground biomass, and decreased weed biomass by 60%. It also demonstrated the second highest amount of BNF (40 g m-2) and soil C increase by 1.5%. On contrary, IF hindered BNF by almost 70% in all legume-containing CC treatments and reduced soil C by 15%.
Study on the impact of digital transformation on green competitive advantage: The role of green innovation and government regulation
Authors: Wu Shaoling , Cheng Peng , Yang Fan
Published: August 2024

Digital transformation enables small and medium enterprises (SMEs) to reduce or overcome their reliance on resources and energy, thereby minimizing their environmental impact and providing them with sustainable green competitive advantages. However, the reasons for this phenomenon are not yet clear. To further investigate this issue, we selected 391 Chinese SMEs to examine the relationships among green transformation, green innovation, government regulation, and green competitive advantages. Green innovation includes green product innovation and green process innovation, while government regulation includes incentive regulation, constraint regulation, and guidance regulation. The empirical results show that digital transformation can enhance SMEs’ green competitive advantages. Additionally, the hypothesized mediating effect of green product innovation and green process innovation between digital transformation and green competitive advantages is supported, while the moderating effect of incentive regulation, constraint regulation, and guidance regulation on the relationship between digital transformation and green product innovation and green process innovation is also confirmed. The findings of this study may contribute to more effective management of digital transformation and green innovation in SMEs, thereby promoting their development.
Identifying the key components of social support for patients living with type 2 diabetes: A protocol for a systematic review and meta-analysis of type 2 diabetes social support interventions
Authors: Madroumi Reda , Newson Lisa , Umeh Frederick Kanayo , Poole Helen , Jones Andrew
Published: August 2024

Type 2 diabetes (T2D) is a disease that impacts a huge portion of the world’s population. The number of T2D cases is expected to keep rising during the next decade. Committing to the treatment to manage this condition makes participants feel a burden of emotions making them require emotional support from caregivers or close ones. Support from family or caregivers can help improve glycaemia control, medication adherence, and T2D self-management. However, little is known about what aspects of social support effectively improve patients’ T2D self-management outcomes. The aim of this systematic review and meta-analysis is to identify the effective components of social support that can help participants improve their T2D self-management. Methods: The protocol of this review was developed based on the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The PRISMA recommendations were applied to develop a search strategy in collaboration with a team of academics to identify relevant T2D social support interventions via healthcare and psychology databases, Medline, Web of Science, ProQuest, CINHAL. Discussion: This review will provide an overview of what intervention social support components have a significant impact on T2D glycaemia control. These findings will inform future T2D interventions on what social support components could be used to encourage better diabetes self-management and glycemic control.
Using Google Street View for virtual observations of neighborhoods and dwelling units: A feasibility study
Authors: Yan Ting , Yang Xin (Rosalynn) , Sun Hanyu , Cantor David
Published: August 2024

In face-to-face household surveys, field interviewers are sometimes asked to make notes of characteristics of the dwelling unit on the sampled address as well as its surroundings before making contact with a household member living at the sample address. Field interviewer observations of this kind are used to improve efficiency of field data collection and to be used as nonresponse adjustment. However, field interviewer observations can be expensive and the quality of observations needs to be improved. Recently, survey organizations start to utilize Google Street View to conduct virtual observations of the dwelling unit and the neighborhood. This paper reports a feasibility study that evaluates the feasibility of using virtual observations, assesses its agreement with field interviewer observation results, and examine whether virtual observations correlate with survey response status and survey estimates. We found moderate to high agreements between virtual and interviewer observation results. We also found that some observation results are significantly related to response status and survey estimates. However, virtual observations using GSV have coverage issues, which could limit their potential use.
Association of IL13 polymorphisms with susceptibility to myocardial infarction: A case-control study in Chinese population
Authors: Chen Rong , Bao Qiaoling , Ma Xiaofeng
Published: August 2024

Background

Inflammatory cytokines play a major role in the pathogenesis of myocardial infarction (MI). Although information on the importance of interleukin 13 (IL13) in human MI is limited, it has been well documented in the mouse model. Genetic variation in the IL13 gene has been associated with the structure and expression of the IL13. In the present study, we hypothesized that IL13 common genetic variants would be associated with a predisposition to the development of MI.

Materials and methods

The present study enrolled 305 MI patients and 310 matched healthy controls. Common genetic polymorphisms in the IL13 gene (rs20541, rs1881457, and rs1800925) were genotyped using the TaqMan SNP genotyping method. Plasma levels of IL13 were measured using an enzyme-linked immunosorbent assay (ELISA).

Results

In MI patients, minor alleles of the IL13 rs1881457 and rs1800925 polymorphisms were less common than in healthy controls [rs1881457: AC (P = 0.004, OR = 0.61), C (P = 0.001, OR = 0.66); rs1800925: CT (P = 0.006, OR = 0.59)]. Further haplotype analysis of three studied SNPs revealed a significant association with predisposition to MI. Interestingly, IL13 rs1881457 and rs1800925 were linked to plasma levels of IL13: the reference genotype had higher levels, heterozygotes were intermediate, and the alternate genotype had the lowest levels.

Conclusions

In the Chinese population, IL13 (rs1881457 and rs180092) variants are associated with different plasma IL13 levels and offer protection against MI development. However, additional research is required to validate our findings in different populations, including descent samples.
Staphylococcus aureus/Staphylococcus epidermidis from skin microbiota are balanced by Pomegranate peel extract: An eco-sustainable approach
Authors: D’Arcangelo Sara , Di Fermo Paola , Diban Firas , Ferrone Vincenzo , D’Ercole Simonetta , Di Giulio Mara , Di Lodovico Silvia
Published: August 2024

The imbalance in skin microbiota is characterized by an increased number of pathogens in respect to commensal microorganisms. Starting from a skin microbiota collection, the aim of this work was to evaluate the possible role of Pomegranate (Punica granatum L.) Peel Extract (PPE) in restoring the skin microbiota balance acting on Staphylococcus spp. PPE was extracted following green methodology by using n-butane and the Dimethyl Ether (DME) solvents and analyzed for phytochemical composition and antimicrobial activity. The PPE antimicrobial action was evaluated against Gram +, Gram − bacteria and yeast reference strains and the most effective extract was tested against the main skin microbiota isolated strains. PPE extracted with DME showed the best antimicrobial action with MICs ranging from 1 to 128 mg/mL; the main active compounds were Catechin, Quercetin, Vanillic acid and Gallic acid. The PPE in DME anti-adhesive effect was examined against S. epidermidis and S. aureus mono and dual-species biofilm formation by biomass quantification and CFU/mL determination. The extract toxicity was evaluated by using Galleria mellonella larvae in vivo model. The extract displayed a significant anti-adhesive activity with a remarkable species-specific action at 4 and 8 mg/mL against S. epidermidis and S. aureus mono and dual-species biofilms. PPE in DME could represent an eco-sustainable non-toxic strategy to affect the Staphylococcal skin colonization in a species-specific way. The innovation of this work is represented by the reuse of food waste to balance skin microbiota.
Hexane extract from black soldier fly prepupae: A novel immunomodulatory strategy against Aeromonas hydrophila infection in zebrafish
Authors: Qosimah Dahliatul , Amri Indah Amalia , Pratama Dyah Ayu Oktavianie A. , Permata Fajar Shodiq , Noorhamdani Noorhamdani , Widasmara Dhelya , Sabri Jasni
Published: August 2024

Background and Aim: Aeromonas hydrophila infections in fish result in significant financial losses within aquaculture. Previous research indicates black soldier fly (BSF) prepupae provide immunomodulatory benefits through their fatty acids, chitin, and proteins. The study evaluated the impact of hexane extract from black soldier fly prepupae (HEBP) on interleukin (IL)-4 and IL-10 cytokine expression in zebrafish, both infected and uninfected with A. hydrophila.

Materials and Methods: Adult zebrafish (aged 4–5 months) was assigned to a negative control group (fed commercial feed), a positive control group (commercial feed + A. hydrophila infection at 107 colony-forming unit/mL), and three treatment groups (T1, T2, T3) that received HEBP at doses of 1000; 2000 and 4000 mg/kg feed for 30 days, respectively. A. hydrophila infection was introduced on day 31 through immersion. Analysis of IL-4 and IL-10 expression in the head kidney trunk region (body without head and tail) through quantitative polymerase chain reaction was conducted on day 33.

Results: The HEBP modulated the immune response to A. hydrophila infection at a concentration of 1000 mg/kg feed, as evidenced by an increase in IL-4 and IL-10 expression in the groups not infected with the bacteria. However, these cytokines were decreased in the infected groups.

Conclusion: A feed concentration of 1000 mg/kg HEBP was identified as optimal for cytokine modulation. This discovery marks a significant advancement in the development and benefit of a natural extract-based immunomodulator in a zebrafish model, which is potentially immunotherapeutic against bacterial infections in fish for the aquaculture industry.

Keywords: Aeromonas hydrophilia, black soldier fly larvae, hexane extract, immune modulation, zebrafish.
Governança Inteligente do Turismo: analisando indicadores em Bonito (MS)
Authors: Juchneski Daniele Paula , Grechi Dores Cristina , Biz Alexandre Augusto
Published: August 2024

O modelo de governança inteligente dos destinos turísticos se fundamenta no alinhamento entre as novas tecnologias da informação e comunicação e a gestão pública do turismo. O objetivo desta pesquisa foi analisar a governança do turismo no Município de Bonito (MS) a partir dos indicadores de governança inteligente, propostos pelo Instituto Valenciano de Turismo (Invat.Tur, 2015, 2017, 2020). O estudo foi desenvolvido por meio da triangulação de fontes: pesquisa bibliográfica, documental e empírica, incluindo entrevista semiestruturada realizada com os atores relacionados à governança do turismo no município. Os resultados demonstram que o sistema de gestão do turismo tem potencial para desenvolver uma governança inteligente, contudo, para que funcione efetivamente será necessário implantar algumas ações, a saber: desenvolver um plano de gestão que contemple os indicadores de governança inteligente do turismo; desenvolver um sistema criando uma teia de dados abertos e transparentes, com dados de diferentes formatos e conteúdo, com informações sobre o funcionamento e a estrutura da administração turística pública e privada; desenvolver campanhas de sensibilização que envolvam residentes, turistas e empresas para alcançar níveis mais elevados de consciência social sobre a importância do turismo.
Recent Trends In E-waste Management: Towards Revolutionizing Global Recycling
Authors: V Nidhi , Jaggal Ashwini , H Rakshith
Published: August 2024

The spectacular developments in modern times have undoubtedly enhanced the quality of our lives. At the same time, these have led to manifold complications. Growth in Information technology and communication sectors has inflated the usage of electronic equipment exponentially. The problem of the massive amounts of hazardous waste generated from electronic products is called E-waste i.e.,” Precious Rubbish” with the presence of indispensable materials in it. In the midst of the electronic revolution, e-waste is one of the meteoric rising issues of the world with estimated proportions of 50 million tonnes per annum approximately. This escalating challenge calls for greater emphasis on recycling and better management. The present concept poster deals with highly advanced techniques of recycling e-waste. However, it is only in the recent era that microorganisms have been applied on a broader magnitude in order to obtain numerous rare and commercial metals. Recycled materials are used as paramount innovations such as batteries in electronic vehicles, medals, eco brick, aluminum handbags, and jewelry. The approach of revolutionary recycling can lead to better prospects and could result in achieving milestones of the social change paradigm.
Ramírez Velázquez, B. R. (2023). Encuentros disciplinarios y debates metodológicos. La investigación crítica sobre las relaciones espacio / territorio
Authors: López Levi Liliana
Published: August 2024

Ramírez Velázquez, B. R. (2023). Encuentros disciplinarios y debates metodológicos. La investigación crítica sobre las relaciones espacio / territorio. México: Universidad Autónoma Metropolitana-Unidad Xochimilco 336 pp. ISBN 978-607-28-2791-2
Wilson, B. (2022). Metrópolis. Una historia de la ciudad, el mayor invento de la humanidad
Authors: Martínez Delgado Gerardo
Published: August 2024

Wilson, B. (2022). Metrópolis. Una historia de la ciudad, el mayor invento de la humanidad. España: Debate 525 pp., ISBN 978-84-18006-47-0
Exposición temporal: Dibújame un mapa de lo que no verás
Authors: Mijares Lara Marcela
Published: August 2024

Exposición temporal: Dibújame un mapa de lo que no verás, Casa del Lago de la UNAM. Primera Sección del Bosque de Chapultepec, s/n, San Miguel Chapultepec, 11850 Ciudad de México [Acceso peatonal por Av. Paseo de la Reforma, puerta principal al Zoológico] Del 8 de junio al 17 de noviembre de 2024
Exposición temporal: El arte de la cartografía en talavera poblana Carolino
Authors: Mendoza Vargas Héctor
Published: August 2024

Exposición temporal: El arte de la cartografía en talavera poblana Carolino. Centro Universitario de la Cultura y de los Saberes Edificio Carolino, primer patio 4 Sur 104, Centro Histórico Puebla, México Del 22 de mayo al 22 de septiembre 2024
Los enemigos de la inmaculada institucionalidad uruguaya
Authors: Castro Ramiro
Published: August 2024

Este trabajo dialoga con los estudios relacionados a la violencia represiva estatal, pues pretende abordar algunos aspectos del estado de excepción previo a la dictadura civil-militar uruguaya que comenzó en 1973; mediante el estudio de la legislación y el uso de fundamentos teóricos e instrumentos represivos aplicados por el Estado entre 1968 y 1972.
Nuevas configuraciones del derecho a pensión en Argentina
Authors: Cóceres Celeste
Published: August 2024

El presente trabajo analiza las pensiones en el derecho previsional argentino, prestaciones de la seguridad social que brindan cobertura frente a la contingencia social de desamparo por muerte. En particular, realiza un recorrido por su surgimiento, su finalidad originaria, y las modificaciones que fue acompañando la agenda pública,  conforme variaron las circunstancias socioculturales. En este devenir se destacan las reformas legislativas y su ampliación por vía jurisprudencial, ante nuevos presupuestos susceptibles de tutela. Asimismo,  se plantea la ineludible revisión de los supuestos, que garanticen la cobertura social frente a las necesidades económicas que genera la contingencia muerte, en equilibrio con la sustentabilidad del sistema y sin perder el foco del fundamento de esta institución.
Modern Perspectives on Hypertrophic Cardiomyopathy—No One Size Fits All
Authors: Doliner Brett , Gaddar Hadeel , Kalil Ramsey , Postalian Alexander
Published: August 2024

Despite substantial advances in the management of hypertrophic cardiomyopathy, advanced heart failure remains a major cause of morbidity in this patient population. This narrative review presents the case of a patient with hypertrophic obstructive cardiomyopathy who underwent alcohol septal ablation to frame a discussion of modern therapies for hypertrophic cardiomyopathy. The current treatment landscape includes medications, both old and new, and surgical and procedural interventions to relieve mechanical obstruction.

Several promising new modalities for relieving obstruction are in the nascent stages of development.
PROBLEMS OF STAFFING OF NON-COMMERCIAL ORGANIZATIONS
Authors: Zakharova Tatiana ,   Plekhanov Russian University of Economics, Sadykova Ksenia , Styurina Daria ,   Plekhanov Russian University of Economics,   Plekhanov Russian University of Economics
Published: August 2024

Personnel management in non-profit organizations is a rather complicated system. Like the business environment, it includes all aspects of human resource management from strategy development and personnel policy to the release of staff, but the difference arises in the fact that compensation is often not fundamental in attracting and retaining staff. The growing popularity of volunteer projects contributes to the development of non-profit organizations around the world, and the significant impact of social pro-jects encourages to delve deeper into the study of this phenomenon. In reality, absolutely all organizational processes in non-profit organizations are related to the management of people. At the same time, there are a number of features that must be taken into account for the effective operation of non-profit organizations. The main problem of human resource management for non-profit organizations is the contradiction be-tween the needs of society in the social sphere, the qualitative renewal of its personnel, and its current state. Few want to build a career exclusively in the non-profit sector because of the low pay. In such struc-tures, non-material incentives, informal communications and the personality of the leader play an im-portant role. The purpose of the study is to analyze the possible problems of personnel management in non-profit organizations and find ways to overcome the inefficiency of non-profit organizations in the development of human resources. The methodological basis of the study was the basic theories and provisions of scientific literature in the field of economics and management. The information base of the study was the expert and statistical data of the analysts of Rosstat of the Russian Federation, ANO “Atlas non-profit organizations”, the Agency for Social Information in recent years. The article analyzes the basic principles, trends and features of hiring non-profit organizations em-ployees, incentives and motivators that work for people who are ready to devote their lives to helping and supporting those in need. The results of the study can be used in socially oriented non-profit organizations to improve the efficiency of existing systems.
ASSESSMENT OF THE ECONOMIC POTENTIAL OF SERVICE ENTERPRISES
Authors: Necheuhina Nadezhda ,   Ural State University of Economics, Mustafina Olga ,   Ural State University of Economics
Published: August 2024

Modern management practice at service enterprises is aimed at developing management decisions that ensure development efficiency, both in the current period and in the strategic perspective. Currently, in the economic literature there are opinions on various systems of indicators that allow for an analytical assessment of the economic potential of service enterprises. At the same time, there is no one frame of mind regarding the system of these key indicators. The relevance of the research topic is determined by the theoretical and practical need to develop a system of key indicators for assessing the economic potential of service enter-prises. To achieve this goal, there is a need to solve the following tasks: firstly, to perform the theoretical analysis of the systems of indicators that characterize the economic potential of enterprises; secondly, de-fine the goals and objectives of assessing the economic potential of enterprises; thirdly, develop a system of indicators for assessing the economic potential of service enterprises. The object of the study are the service enterprises, which ensure the process of formation of the system of economic potential. The subject of the study is the system of accounting and analytical support, thanks, to which the necessary accounting and analytical information is formed, which is the basis for assessing the economic potential of service en-terprises. In the course of the study, general and private methods (observation, comparison, experiment and description) have been used. The use of these research methods allowed the authors to compare the exist-ing theoretical provisions for assessing the economic potential of service enterprises, as well as to develop a scientifically based opinion on the most significant criteria for assessing economic potential. The practi-cal significance of the study lies in the development of a scientifically based position, assessment of the economic potential of service enterprises; the results of such an assessment form an analytical judgment about the level of socio-economic development and the possibilities of such development of an individual economic entity (service sector enterprise). Directions for further research are aimed at developing scientif-ically based views for assessing the economic potential of service enterprises in the system of universal and integrated indicators.
IMPACT OF INNOVATION AND INVESTMENT ACTIVITIES ON THE DEVELOPMENT OF ENTREPRENEURSHIP
Authors: Gelrud Yakov ,   South Ural State University, Jianan Cui ,   South Ural State University
Published: August 2024

At present, it is recognized all over the world that innovations are the first driving force for the development of both the state and enterprises. In this article, using the methodology of empirical re-search, using the financial data of selected companies, the role of innovative investments in the qualitative development of enterprises is analyzed. A hypothesis has been put forward and substantiated that innovative investments can effectively stimulate the qualitative development of enterprises, and the regulation of differ-ences in property rights can lead to differences in the degree of stimulation and to an increase in the efficien-cy of innovative activity of private enterprises. This article first examines the theoretical question of the im-pact of innovation on the qualitative development of enterprises, and then examines the relationship between them through empirical research. This study provides an opportunity to understand the Chinese theory of in-novative investment and development of high-quality enterprises, to help enterprises take a less evasive path, to give them guidance on innovative investment to maintain their competitive advantage. The government should also strongly support enterprises' investment in innovation in order to achieve the goal of qualitative development of the Chinese economy.
INFLUENCE OF THE CAPACITY OF REGULATED CROSSINGS ON THE QUANTITY OF EXHAUST GASES FROM VEHICLES
Authors: Shepelev Vladimir ,   South Ural State University, Glushkov Alexander , Fadina Olga , Kutuzova Vitalina ,   South Ural State University,   South Ural State University,   South Ural State University
Published: August 2024

The ability to monitor the condition of individual road sections in the urban environment in or-der to manage traffic congestion more effectively is becoming increasingly important. At present, complex traffic management systems are being developed that can process data from both static and mobile sensors and provide traffic information for the road network. In addition to typical traffic data such as traffic flow, densi-ty and average speed, there is currently a great interest in environmental factors such as greenhouse gases, pollutant emissions and fuel consumption. In this work, monitoring using surveillance cameras of street sur-veillance with the help of convolutional neural networks is proposed. Testing of the system under various conditions showed an absolute percentage accuracy of detection and classification of vehicles, at least 92 %. As a result of the research, the most significant factors have been identified, by controlling which it is possi-ble to effectively influence the traffic lane capacity. A method for calculating the time of passing-by of the queue of non-group vehicles is proposed and the effect of acceleration on throughput is investigated, which will reduce the likelihood of congestion at regulated intersections. Studies have been conducted on the influ-ence of the speed of passage by motor vehicles of the nodes of the road network on the amount of emissions of pollutants into the atmosphere.
ADVANCED DEVELOPMENT STRATEGY IN EXPANDED MODELS REPRODUCING LABOR RESOURCES
Authors: Lavrentieva Irina ,   Chelyabinsk Branch of the Russian Academy of National Economy of Public Administration under the President of the Russian Federation, Topuzov Nikolai ,   Chelyabinsk Branch of the Russian Academy of National Economy of Public Administration under the President of the Russian Federation
Published: August 2024

This article reveals the content and conditions for the effective implementation of models re-producing labor resources that meet the requirements of the new technological structure. The research meth-odology is based on the principles of continuity, unification, rhythm, and consistency. The features, specific-ity, and shortcomings of existing models based on the transformation of objects of regulation, the influence of demographic, family, and reproductive-oriented approaches are substantiated. An analysis of the ele-ments, structure, stages, intercomponent connections, technologies and tools for regulating the reproduction of labor resources allows us to assess the shortcomings of linear, linear-adaptive, and iterative models based on types of reproduction, which contradicts the requirements of an innovative economy. The interactive model, which is based on the coordination and synchronization of network interaction between process participants, is represented by an integral set of two complementary reproductive subsystems – reproduc-tive (accounting for the results of parental labor) and that functioning in the real sector of the economy (in-dividual and group development trajectories and targeted specialization). By decomposing the model ele-ments, the authors identified the time compression during the reproduction of labor resources, which makes it possible to implement a strategy of advanced development on the basis of the reproduction of la-bor resources.
FORESIGHT RESEARCH TECHNOLOGY OF THE COMMODITY MARKET: A CASE STUDY ON TRENDS IN THE RUSSIAN BICYCLE MARKET
Authors: Sinyavets Tatyana ,   Dostoevsky Omsk State University
Published: August 2024

Foresight research into commodity markets is being changed by the restructuring of the Russian economy given global changes in the world order and requires further development. This article presents fore-sight research of the commodity market using ISM methodology, SWOT analysis, and the scenario method. As a case study, the product market of bicycles is considered as a typical market for consumer durables. Current trends in the commodity market with sanctions against Russia have been established. The basic provi-sions of the foresight study were successfully supplemented with a scenario prototype of market trends and the re-sults of management techniques, which made it possible to form a problem field for the bicycle market in Russia, considering supply and demand, and to develop pessimistic, optimistic, and basic scenarios for its development. The results of the study are relevant for entrepreneurs when making decisions on the development of new types of business, for local governments to develop urban infrastructure to maintain a healthy lifestyle culture.
THE TRANS-ARCTIC RAILWAY PROJECT: A COALITION ANALYSIS OF INVESTOR INTERACTIONS
Authors: Kibalov Evgeny ,   Institute of Economics and Industrial Engi-neering (IEIE) SB RAS, Gelrud Yakov , Shibikin Dmitry ,   South Ural State University,   Siberian Transport University
Published: August 2024

This study investigates the conditions for construction financing by private contractors of the western wing of the Transpolar route from Salekhard to Norilsk. The purpose of the article is to con-sider the complex interaction between the customer and expert groups when choosing contractors in condi-tions of limited investment, using the example of a large-scale railway project (LSRWP) Northern Latitu-dinal Way (NLW). The methodology is based on converting expert rankings in an ordinal scale into a nu-merical format, in the form of coefficients of the relative importance (CRI) using ORDEX software. The Shapley method is also considered, which affects the unions of contractors in different coalitions, and en-sures the reliable and timely implementation of the LIP-railway. The result of the work is a comparison of a fair compromise according to Granberg and a compromise according to Shapley, which makes it possible to expand the depth and quality of the analysis for cases when compromises do or do not coincide. The tools allow the customer at the pre-investment stage of the evaluation of LSRWP to structure uncertainty and, using decision theory, evaluate the project first in a situation of probabilistic uncertainty, and then in a situation of improbable (radical) uncertainty. Such an integrated approach allows the customer to avoid catastrophic errors at the pre-investment stage of evaluating projects of this class. The usefulness of the result for the customer lies in the ability to make informed decisions when dis-tributing a fixed amount of investment between contractors. This ensures, when united into different tech-nologically feasible coalitions, stability and reliability in implementing the project.
Effect of climate on variation of oil crop production in Anbar Governorate
Authors: Alalosy Bilal Muayad Abdulrahem , Daood Sulaf Taha , Mohamed Mohammed Rahim , Al-Karbouli Ali Suleiman Erzik , Ahmad Jumaa Mohammed , Abdel Ghani Emad T
Published: August 2024

The different elements of climate have an effective impact on the nature and quality of cultivated crops in any region and this effect is reflected by determining the thermal, photovoltaic, and water requirements and the time of germination and growth for each crop, The results show that there is a difference in climatic conditions in each of the study stations within Anbar Governorate, and this variation is evident in the climatic elements affecting the growth and maturity of oily crops, especially the general average temperature and the maximum and minimum temperature rates, which increased in 2022 compared to the year 2000. In the shadow of the decrease in the amounts of rain from what it was in the past, this difference was reflected in the quantities of production between those years, as the output in the year 2000 was more than the amount of production in the year 2022 for all crops, so the amount of production for the Maize crop in the year 2000 was (22620) tons, while in the year 2022 (16450) tons, while the sunflower crop was (40.6) tons, while in the year 2022 (15.1) tons, and the cotton crop in the year 2000 was (57.6) tons, while the production reached in 2022 (11.1) tons, the sesame crop in the year 2000 (1873) and in the year 2022 (210.3) tons.
Comparing the efficacy, safety, and satisfaction for moderate to severe glabellar frown lines between abobotulinum toxin A and incobotulinum toxin A: a multicenter randomized study
Authors: Lee Jong Hun , Lee Seo Koo , Kim Sang Hun , Lee Sun Jae , Kim Jun Hyun , Park Eun Soo
Published: August 2024

Background Botulinum toxin type A is widely used to improve facial wrinkles associated with aging, and various types are available. However, the efficacy, particularly the duration of effect, varies among these types, and research on this subject is limited. This study aimed to compare the efficacy and safety of incobotulinum toxin A and abobotulinum toxin A.Methods This prospective analysis included cases of moderate to severe glabellar lines treated with either incobotulinum toxin A or abobotulinum toxin A. After a 24-week follow-up, clinical photos were taken at each visit. The severity of the glabellar lines was evaluated by three groups: the investigator, the patients, and an independent evaluator.Results The study included a total of 42 patients. When comparing the improvement rates of glabellar lines at maximum frown for both groups at the week-4 visit, which was the primary efficacy endpoint, no statistically significant difference was observed. However, the abobotulinum toxin A group demonstrated a higher improvement at the week-24 visit, as evaluated by the investigator, and this difference was statistically significant.Conclusions Overall, the abobotulinum toxin A group exhibited a higher improvement rate in the glabellar lines at the frown state. The difference in the improvement rate at the week-24 visit was 36.86%, which was statistically significant.
The TOM complex from an evolutionary perspective and the functions of TOMM70
Authors: Özdemir Metin , Dennerlein Sven
Published: August 2024

In humans, up to 1,500 mitochondrial precursor proteins are synthesized at cytosolic ribosomes and must be imported into the organelle. This is not only essential for mitochondrial but also for many cytosolic functions. The majority of mitochondrial precursor proteins are imported over the translocase of the outer membrane (TOM). In recent years, high-resolution structure analyses from different organisms shed light on the composition and arrangement of the TOM complex. Although significant similarities have been found, differences were also observed, which have been favored during evolution and could reflect the manifold functions of TOM with cellular signaling and its response to altered metabolic situations. A key component within these regulatory mechanisms is TOMM70, which is involved in protein import, forms contacts to the ER and the nucleus, but is also involved in cellular defense mechanisms during infections.
Quality of outcome (QoO) in oral cancer patients: prospective perioperative analysis of patients’ resilience and satisfaction during inpatient stay at a University Medical Centre in Germany
Authors: Kröplin Juliane , Reppenhagen Jil-Charlot , Hirsemann Anke , Liese Jan , Frerich Bernhard
Published: August 2024

Objectives

Quality assurance strategies for head and neck surgery can improve patient outcomes. This study aims a perioperative analysis of indicators in the quality of outcome in oral cancer patients with special focus on patient`s resilience and satisfaction before and after surgery.

Methods

Patients with oral cancer (OCP) and indication for surgical resection were included in a prospective study. General and disease-related data as well as parameters of patient-specific resilience (RS-11 questionnaire) and physical strength (ECOG-Score) were collected. Importance and satisfaction using the nine items family/friends, sports activities/physiotherapy, participation in culture, professional perspectives, sexuality, enjoyable food, external appearance, social recognition and independence were analysed. The data collection took place pre- and postoperatively (mean: 10th postop day) during the inpatient stay.

Results

Twenty-eight patients with oral cancer (OCP) were analysed (male: n=23, female n=5). The rate of R0 resections was 92.6 %. The average length of stay was 21 days. n=16 of all patients was tracheotomised postop (preop: n=0). n=0 patients confirmed psycho(onco)logical support preop (postop: n=19). Sports activities/physiotherapy was provided to n=3 patients preop (postop: n=21). The mean pre and postop pain perception was 3/10. The RS-11 score decreased significantly postoperatively (p=0.01). A significant loss of satisfaction was seen in the areas of enjoyable food (p<0.001), social recognition (p=0.01), external appearance (p=0.01) and independence (p<0.001).

Conclusions

Supportive therapy measures to promote mental and physical fitness of oral cancer patients are part of inpatient care at our clinic. However, there is no standardised monitoring of these therapies. Digitally supported and standardised programmes to increase mental and physical fitness in both prehospital and inpatient care might lead to an improvement in the quality of outcome despite shortage of resources in terms of time, costs and personnel. A minimally invasive approach to tracheal cannula management and lymph node management in the treatment of OCP can help to reduce the length of stay in the intensive care unit.
Ambivalent Utopias: Corporate Biopower and the Gendered Limits of Agency in Reset
Authors: Lei Jun
Published: August 2024

This article examines Reset (逆时营救, 2017), a Chinese science fiction film that diverges from the genre’s typical patriotic themes. Reset offers a compelling case study for exploring technoscience’s impact – as a tool of corporate biopower and neocolonialism – on human corporeality, subjectivity, and female agency. The film’s protagonist, Xia Tian, transforms from a career-focused scientist to time-traveling cyborgs, ultimately reverting to a traditional maternal role. Analyzing this trajectory through Foucault’s biopower, Haraway’s cyborg feminism, and contemporary theories on reproductive futurism and sacrificial motherhood, the study unveils Reset’s function as an allegorical lens. It magnifies the effects of global corporate biopower on human subjectivity, particularly female agency amid apocalyptic upheavals. Xia Tian’s journey illustrates the complexities professional women face in balancing career and family, reflecting broader societal issues and mirroring Chinese cultural imperatives that simultaneously valorize motherhood and women’s workforce participation. Reset performs a double movement: introducing alternative forms of womanhood via cyborg iterations while framing these as incompatible with the envisaged societal future. This paradox highlights the film’s ambiguous stance, critiquing neocolonial capitalism’s manipulation of human bodies while exhibiting a conservative approach to gender roles.
Perceived quality of a nighttime hospital soundscape
Authors: Lenzi Sara , Lindborg PerMagnus , Spagnol Simone , Kamphuis Daan , Özcan Elif
Published: August 2024

The hospital soundscape is known for high noise levels and a perception of chaos, leading to concerns about its impact on patients, families, professionals, and other hospital staff. This study investigates the relationship between sound, Annoyance, and sleep quality in a multi-patient neurology ward. A mixed-methods approach was employed. Interviews were conducted with medical staff (n = 7) to understand their experiences with sound. Questionnaires and sleep tracking devices (n = 20) assessed patient sleep quality and Annoyance caused by sound events. In addition, listeners (n = 28) annotated 429 nighttime audio recordings to identify sound sources and rate Annoyance level, which we considered the key emotional descriptor for patients. Over 9,200 sound events were analysed. While snoring, a patient-generated sound dominated the nighttime soundscape and was highly rated for Annoyance, and staff-generated sounds such as speech and footsteps were found to contribute more to accumulated Annoyance due to their extended duration. This study suggests that patient sleep quality can be improved by focusing on design interventions that reduce the impact of specific sounds. These might include raising awareness among staff about activities that might produce annoying sounds and implementing strategies to mitigate their disruptive effects.
Parameter optimization for ultrasonic-assisted grinding of γ-TiAl intermetallics: A gray relational analysis approach with surface integrity evaluation
Authors: Yang Song , Zhang Guangjin , Xiao Guoqing
Published: August 2024

The processing of γ-TiAl intermetallic compound (Ti–45Al–2Mn–2Nb) is essential for manufacturing aircraft engine components, known for their challenging machinability. This study delved into the machining performance of γ-TiAl intermetallic compound through ultrasonically assisted grinding experiments. Various grinding parameters, such as wheel rotation speed (v
s), feed rate (v
w), depth of grinding (a
p), and ultrasonic amplitude (A), were investigated to understand their effects on grinding forces, temperatures, and surface quality. Gray relational analysis (GRA) and analysis of variance were used to analyze experimental data and ascertain the optimal machining parameters for ultrasonically assisted grinding of γ-TiAl intermetallic compound. Additionally, post-processing surface integrity, encompassing surface roughness, morphology, and residual stresses, was evaluated. The optimal grinding parameter combination was determined as F
n = 3.22 N, F
t = 1.08 N, and T = 174°C through GRA. Under the selected machining conditions, the depth of cut exerted the most significant influence on the grinding force and temperature, while the effect of wheel speed was the weakest. The surface roughness (Ra) of the workpiece increased with increasing feed rate and depth of the cut but decreased gradually with increasing wheel speed. Upon applying ultrasonic vibration, there was a notable decrease in surface roughness, ranging from 20.12 to 7.67%. However, the increase in the wheel speed, depth of cut, and feed rate inhibited the reduction of roughness due to ultrasonic vibration. Ultrasonic vibration effectively reduced the profile height of the workpiece surface, with a maximum reduction of 1.94 μm within the selected range. Nonetheless, as the wheel speed, depth of cut, and feed rate increased, the effectiveness of this reduction gradually diminished.