bluuebunny/crossref_metadata_2025 huggingface dataset:
GRAFENO: MATERIAL PROMISSOR NA ODONTOLOGIA
Authors: DANIEL RAMALHO DA SILVA  , JOÃO VITOR GUIMARÃES ROCHA  , ROCHA RODRIGUES MURILO , LUCAS DANTAS RUAS
Published: October 2023

O grafeno é uma das formas cristalinas do carbono, assim como o diamante, o grafite, os nanotubos de carbono e fulerenos. É reputado como um dos materiais mais promissores nas áreas da nanoquímica, nanoengenharia e nanobiologia. Possui elevada resistência mecânica e porosidade, além de rigidez e biocompatibilidade, qualidades que lhe confere competência nas áreas da odontologia: implantodontia, periodontia e dentística. O objetivo dessa revisão de literatura foi investigar as vantagens e desvantagens deste material, descrever suas características, em relação as suas propriedades físico-químicas visando relatar as possibilidades acerca da utilização e aplicação desse material no âmbito odontológico.
BENEFÍCIOS DA FISIOTERAPIA NEUROFUNCIONAL NO ATENDIMENTO DE PACIENTES COM SÍNDROME DE TOURETTE
Authors: Danielly Diniz Souza e Silva  , Alves de Oliveira Welton Alves de Oliveira , Araújo Vandy Winglinton Araújo Vandy , Montezzano Valintin Lacerda Rodrigo Antônio , Pereira de Faria Alice Pereira de Faria
Published: October 2023

A síndrome de Tourette é uma doença genética que afeta o sistema nervoso e se caracteriza por crises compulsivas, incluindo tiques motores e vocais, que podem prejudicar a vida psicológica e social do indivíduo. A síndrome, que geralmente começa antes dos dezoito anos, é incurável, mas controlável, e também pode ser acompanhada por sintomas obsessivo-compulsivos, dificuldades de aprendizagem e transtorno de atenção e hiperatividade. Frente a essa observação este estudo teve como objetivo descrever os benefícios da fisioterapia no cuidado de pacientes com síndrome de Tourette. Trata-se de um estudo bibliográfico, de natureza qualitativa e com fins descritivo, que foi produzido por meio de artigos científicos das bases de dados SciELO e Google Acadêmico. Para o levantamento bibliográfico, foram utilizadas as seguintes palavras-chave combinadas: Síndrome de Tourette; Fisioterapia; Reabilitação; Neurofuncional. Por fim, foram identificados os paralelos entre essa perspectiva teórica sobre a atenção e a abordagem postulada para o controle motor na fisioterapia neurofuncional, deste modo considerou-se que os benefícios que podem ser trazidos para os pacientes tais como: maior consciência corporal dos músculos ao redor dos sintomas; controle dos músculos, postura e respiração, relaxamento e fortalecimento Muscular, controle da dor e sobrecarga muscular, e a tradução da informação sensorial em resposta motora mais adequada.
A MATERNIDADE E SEUS IMPACTOS PSICOLÓGICOS NA DEPRESSÃO PÓS PARTO
Authors: Maria Tereza Oliveira Silverio  , Leticia Mendes Paiva
Published: October 2023

A DPP é uma condição que muitas mulheres enfrentam após o nascimento de seus bebês. No entanto, é uma condição que pode ser tratada desde o início da gestação como parte da prevenção da saúde emocional. Ela representa um fator relevante no cuidado com a saúde das mulheres, mas muitas vezes não recebe a devida atenção e tratamento, pois ainda é percebida como um tabu na sociedade. A promoção de iniciativas como o pré-natal psicológico poderia ser uma sugestão importante para políticas públicas de saúde no país, pois, aliadas ao pré-natal básico e a uma boa rede de apoio social, essas iniciativas poderiam prevenir muitos problemas sociais no Brasil e reduzir as taxas de mortalidade materna e perinatal. Em primeiro lugar, foram definidos critérios de inclusão para a seleção de estudos, como o período de publicação de 2013 a 2023, tipos de fontes (artigos científicos, teses, livros, etc.) e idiomas Português e Inglês. Em seguida, foi conduzida pesquisas sistemáticas em bases de dados acadêmicas, como PubMed, Scopus, PsycINFO e Google Scholar. A gravidez se caracteriza por substanciais flutuações hormonais, que, imediatamente após o parto, diminuem de forma acentuada. Juntamente com essas transformações físicas, uma série de variáveis psicológicas impacta o comportamento e o estado de ânimo da mulher, que se vê diante de novas responsabilidades associadas ao cuidado com o recém-nascido. O papel do psicólogo no tratamento da DPP é de suma importância. Entre as abordagens terapêuticas, destaca-se a Terapia Cognitivo-Comportamental, que possibilita a reconstrução da visão da paciente sobre sua realidade, ou seja, seus pensamentos relacionados à maternidade.
反思 2020-2030 年粮食和农业：植物和动物第二次驯化、奶牛养殖、工业化畜牧业的中断
Authors: Tubb Catherine , Seba Tony
Published: October 2023

美国的奶牛数量到 2030 年将下降 50%，畜牧业几乎破产。其他所有畜牧业都将遭遇类似的命运，而对整个价值链中的作物种植者和企业来说更是将造成严重的连锁反应。 《反思粮食与农业》表明精密生物学的快速发展和我们称之为“粮食即软件”的全新生产模式所带来的现代食品干扰将如何对工业化农业产生深远影响，同时还对更广泛的经济、社会和环境产生深远影响。
Exploration of Environmental Design Teaching Mode Based on Case Study
Authors: Xiao Xuebing
Published: October 2023

With the continuous development and progress of society, environmental design plays an increasingly important role in shaping livable cities, improving people's quality of life, and protecting the natural environment. However, the traditional teaching mode of environmental design is often teacher-centered, often ignoring the students' subjectivity and practical ability cultivation, while the teaching mode based on case study brings new ideas and methods for environmental design education. In this paper, we will discuss the advantages of the environmental design teaching mode based on the case study, and conduct an in-depth study on the preparation of teaching resources, construction of cases, and teaching implementation, to provide useful reference and inspiration for advancing the innovation and development of environmental design education.
Los Efectos de la Terapia Cognitivo-Conductual en la Ansiedad Social en Adolescentes
Authors: Silva Méndez Ana
Published: October 2023

El objetivo de esta investigación fue analizar la ansiedad social en la población y determinar su impacto en la vida diaria. Se realizó un estudio transversal utilizando un cuestionario para evaluar la frecuencia y la intensidad de los síntomas de ansiedad social en diversas situaciones sociales. La muestra fue de 100 personas de entre 18 y 50 años, de ambos géneros y de diferentes niveles socioeconómicos. Los resultados indican que un alto porcentaje de personas experimenta ansiedad social en diversas situaciones cotidianas. En particular, hablar en público y hacer presentaciones son situaciones que generan un alto nivel de ansiedad en las personas encuestadas. Asimismo, se encontró que la ansiedad social afecta negativamente la capacidad de las personas para manejar situaciones sociales estresantes, y que muchos encuestados han evitado situaciones sociales por miedo o ansiedad. La ansiedad social es un problema importante que afecta a muchas personas en su vida diaria, limitando su capacidad para interactuar con los demás y desarrollarse en su trabajo y en su vida personal. Esta investigación destaca la importancia de identificar y tratar la ansiedad social, y sugiere que se necesitan más programas de prevención y tratamiento para abordar este problema.
MATHEMATICAL MODELING AND COMPUTATIONAL EXPERIMENT OF THE PROCESS THE ATMOSPHERIC TRANSPORT OF SALT-DUST AEROSOLS FROM THE ARAL SEA BASIN
Authors:   Dilshot Akhmedov, Sharipov Daler
Published: October 2023

Atmospheric transport of salt-dust aerosols is a sophisticated effect mainly depending on the meteorological situation. Since the dried bottom of the Aral Sea is considered as emissions source, precisely the wind removal of aerosol particles is implied here. It should be noted that the wind erosion of the ground cover can be considered as a special case of the hydrodynamics of multiphase flows, which is of particular scientific interest. In this regard, vertical wind profile, which depends on the roughness of the ground cover and the stability of the atmosphere, become to one of essential aspects for outdoor airflow simulations. Thus, the aim of this work is to study the influence of the vertical wind profile on the atmospheric transport of salt-dust aerosols. The results of computational experiments on the airflow characteristics at various heights, values of the ground-level wind speed and the roughness coefficient are presented in the paper. As well as the results of numerical calculations demonstrating the influence of the horizontal and vertical components of the wind speed on the distribution of suspended aerosol particles within the considered area.
Implikasi Tekanan Kepada Pengamal Pemulihan: Analisis Terhadap Keletihan Emosi, Mekanisme Daya Tindak dan Sokongan Pekerjaan
Authors:   Jabatan Dakwah dan Pembangunan Insan, Akademi Pengajian Islam, Universiti Malaya 50603 Kuala Lumpur, MALAYSIA, Yusmini Md. Yusoff  , Nur Akmal Zakiah Ahmad  ,   Jabatan Dakwah dan Pembangunan Insan, Akademi Pengajian Islam, Universiti Malaya 50603 Kuala Lumpur, MALAYSIA, Tengku Sarina Aini Tengku Kasim  ,   Program Pendidikan Islam, Akademi Pengajian Islam, Universiti Malaya 50603 Kuala Lumpur, MALAYSIA
Published: October 2023

Profesion hubungan menolong yang menjurus kepada aspek pemulihan berpotensi mendedahkan para pengamal kepada tekanan. Sifat kerja yang sentiasa berhadapan dengan isu-isu kemanusiaan yang kompleks dan rumit memberi implikasi tertentu kepada golongan tersebut. Justeru, artikel ini membincangkan tentang sindrom keletihan emosi, mekanisme daya tindak dan sokongan pekerjaan yang diambil dan dapat dicapai oleh para pengamal pemulihan yang berdepan dengan kes-kes penyimpangan agama. Metode kajian yang digunakan adalah bersifat kualitatif melalui penggunaan teknik temu bual mendalam. Seramai sepuluh informan terdiri daripada pengamal pemulihan Muslim di sekitar Selangor dan Wilayah Persekutuan, Putrajaya terlibat dalam kajian ini. Analisis dapatan kualitatif dijalankan secara deskriptif dan hasil kajian mendapati sindrom keletihan emosi memberi kesan signifikan kepada para pengamal pemulihan sama ada secara profesional atau personal.
Needs Analysis Review: Constructs of Integrated Principal Leadership Model and Counselling Approach
Authors:   School of Applied Psychology, Social Work and Policy Universiti Utara Malaysia, Mohd Shahid bin Ahmad  , Rosliza Ahmad  ,   School of Applied Psychology, Social Work and Policy Universiti Utara Malaysia, Fatimah Zailly Ahmad Ramli  ,   School of Applied Psychology, Social Work and Policy Universiti Utara Malaysia
Published: October 2023

The needs analysis study was carried out to investigate the issues related to principal leadership and counselling that led to the need for constructing the Integrated Principal Leadership Model and Counselling Approach (M-KIPK) which was developed using the design and development research (DDR). This study was carried out qualitatively and quantitatively. In the needs analysis phase, data collection was conducted through questionnaires distributed to 282 participants from eight (8) MRSMs in Perak. Descriptive statistics namely frequency and percentage were used to analyse the data while the qualitative study involved interviews of 13 participants who have had experience in leadership and counselling. The findings showed that the participants’ confidence on the need for counselling approach in principal leadership practice and that counselling knowledge would improve the administrative quality of principals was high with mean values of 4.46 or 97.90% and 4.52 or 98.50% respectively. In conclusion, the construction of the M-KIPK Model is necessary in the management of the principal leadership in the school with the inclusion of the counselling constructs. Therefore, the implementation of the M-KIPK Model will assist principals in improving their leadership qualities.
Monitoring Scheme for Safety Hazard Status of Urban Rail Transit Operation Equipment and Facilities Based on Blockchain Technology
Authors: Li Meng , Lin Qi
Published: October 2023

Urban rail transit plays a very important role in cities’ social and economic development. To ensure the safe and stable operation of urban rail transit operation equipment and facilities, it is necessary to monitor a large number of safety hazard statuses and data and improve the over-centralisation of traditional monitoring. This paper designs a scheme for storing, validating and monitoring the safety hazard status of urban rail transit operation equipment and facilities based on blockchain technology. The safety hazards of equipment and facilities during the operation stage of urban rail transit are listed using the literature analysis method and the case study method. The European RAMS (reliability, availability, maintainability and safety) standard method is used to determine the safety hazard status of equipment and facilities by availability index. Based on the features of the consensus mechanism, smart contract and other features of blockchain technology, this paper designs an overall scheme for storing, verifying and monitoring the safety hazard status of equipment and facilities. This scheme provides a practical operation method for evaluating the safety hazard status of rail transit equipment and facilities, which is conducive to the safety rectification of the entire urban rail transit.
Evaluation of Stated Preference Surveys with Statistical Methods
Authors: Sipos Tibor
Published: October 2023

In this paper, the author investigated the stated preference survey in transport modelling. The research was conducted to ensure that the best fractional orthogonal design of stated preference paired comparison survey would not increase the error or uncertainty in transport-related decision modelling. The research was conducted based on artificial Monte Carlo simulated respondents, and the results were assessed with standard mathematical-statistical tools. Although the assessment should have resulted in 0% errors, according to our 2,000 sample, a minor 5% of errors occurred. The problem to be investigated in this paper is that the best-designed survey could have some errors.
Alterations in cortical excitability during pain: A combined TMS-EEG Study
Authors: Chowdhury Nahian S , Chiang Alan KI , Millard Samantha K , Skippen Patrick , Chang Wei-Ju , Seminowicz David A , Schabrun Siobhan M
Published: October 2023

Transcranial magnetic stimulation (TMS) has been used to examine inhibitory and facilitatory circuits during experimental pain and in chronic pain populations. However, current applications of TMS to pain have been restricted to measurements of motor evoked potentials (MEPs) from peripheral muscles. Here, TMS was combined with electroencephalography (EEG) to determine whether experimental pain could induce alterations in cortical inhibitory/facilitatory activity observed in TMS-evoked potentials (TEPs). In Experiment 1 (n = 29), multiple sustained thermal stimuli were administered to the forearm, with the first, second and third block of thermal stimuli consisting of warm but non-painful (pre-pain block), painful (pain block) and warm but non-painful (post-pain block) temperatures respectively. During each stimulus, TMS pulses were delivered while EEG (64 channels) was simultaneously recorded. Verbal pain ratings were collected between TMS pulses. Relative to pre-pain warm stimuli, painful stimuli led to an increase in the amplitude of the frontocentral negative peak ∼45ms post-TMS (N45), with a larger increase associated with higher pain ratings. Experiments 2 and 3 (n = 10 in each) showed that the increase in the N45 in response to pain was not due to changes in sensory potentials associated with TMS, or a result of stronger reafferent muscle feedback during pain. This is the first study to use combined TMS-EEG to examine alterations in cortical excitability in response to pain. These results suggest that the N45 TEP peak, which indexes GABAergic neurotransmission, is implicated in pain perception and is a potential marker of individual differences in pain sensitivity.
The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
Authors: Tejeda-Munoz Nydia , Azbazdar Yagmur , Monka Julia , Binder Grace , Dayrit Alex , Ayala Raul , O'Brien Neil , De Robertis Edward M
Published: October 2023

Activation of the Wnt pathway lies at the core of many human cancers. Wnt and macropinocytosis are often active in the same processes, and understanding how Wnt signaling and membrane trafficking cooperate should improve our understanding of embryonic development and cancer. Here, we show that a macropinocytosis activator, the tumor promoter phorbol 12-myristate 13-acetate (PMA), enhances Wnt signaling. Experiments using the Xenopus embryo as an in vivo model showed marked cooperation between the PMA phorbol ester and Wnt signaling, which was blocked by inhibitors of macropinocytosis, Rac1 activity, and lysosome acidification. Human colorectal cancer tissue arrays and xenografts in mice showed a correlation of cancer progression with increased macropinocytosis/multivesicular body/lysosome markers and decreased GSK3 levels. The crosstalk between canonical Wnt, focal adhesions, lysosomes, and macropinocytosis suggests possible therapeutic targets for cancer progression in Wnt-driven cancers.
Interface-acting nucleotide controls polymerization dynamics at microtubule plus- and minus-ends
Authors: McCormick Lauren A , Cleary Joseph M , Hancock William O , Rice Luke M
Published: October 2023

GTP-tubulin is preferentially incorporated at growing microtubule ends, but the biochemical mechanism by which the bound nucleotide regulates the strength of tubulin:tubulin interactions is debated. The ‘self-acting’ (cis) model posits that the nucleotide (GTP or GDP) bound to a particular tubulin dictates how strongly that tubulin interacts, whereas the ‘interface-acting’ (trans) model posits that the nucleotide at the interface of two tubulin dimers is the determinant. We identified a testable difference between these mechanisms using mixed nucleotide simulations of microtubule elongation: with self-acting nucleotide, plus- and minus-end growth rates decreased in the same proportion to the amount of GDP-tubulin, whereas with interface-acting nucleotide, plus-end growth rates decreased disproportionately. We then experimentally measured plus- and minus-end elongation rates in mixed nucleotides and observed a disproportionate effect of GDP-tubulin on plus-end growth rates. Simulations of microtubule growth were consistent with GDP-tubulin binding at and ‘poisoning’ plus-ends but not at minus-ends. Quantitative agreement between simulations and experiments required nucleotide exchange at terminal plus-end subunits to mitigate the poisoning effect of GDP-tubulin there. Our results indicate that the interfacial nucleotide determines tubulin:tubulin interaction strength, thereby settling a longstanding debate over the effect of nucleotide state on microtubule dynamics.
Human receptive endometrial organoid for deciphering the implantation window
Authors: Zhang Yu , Zhao Rusong , Yang Chaoyan , Song Jinzhu , Liu Peishu , Li Yan , Liu Boyang , Li Tao , Yin Changjian , Lu Minghui , Hou Zhenzhen , Zhang Chuanxin , Chen Zi-Jiang , Wu Keliang , Zhao Han
Published: October 2023

Human endometrial receptivity is a critical determinant of pregnancy success; however, in vivo studies of its features and regulation are particularly challenging due to ethical restriction. Recently, the development of human endometrial organoids has provided a powerful model to examine this intricate biological process. In this study, we established a specialized human window-of-implantation (WOI) endometrial organoid system that mimics the in vivo receptive endometrium. The endometrial organoid recapitulates not only the structural attributes of glands and stroma, but also the in vivo endometrium’s cell types at the single-cell level. Furthermore, the WOI endometrial organoid exhibits the features of in vivo implantation endometrium such as hormone responsiveness, secretory functions, and distinctive implantation window hallmarks, including decidualization, extracellular matrix (ECM) remodeling, pinopode formation, cilia generation and metabolism. This in vitro model also effectively demonstrates the process of proliferation-secretory transformation, ciliary epithelium differentiation, and epithelial-mesenchymal transition (EMT). As such, WOI organoids hold great promise as a robust platform to unravel the intricate mechanisms governing endometrial receptivity regulation, maternal-fetal interactions, and associated diseases, ultimately driving impactful advancements in the field.
Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase
Authors: Boulet Manon , Gilbert Guerric , Renaud Yoan , Schmidt-Dengler Martina , Plantié Emilie , Bertrand Romane , Nan Xinsheng , Jurkowski Tomasz , Helm Mark , Vandel Laurence , Waltzer Lucas
Published: October 2023

N6-methyladenine (6mA) DNA modification has recently been described in metazoans, including in drosophila, for which the erasure of this epigenetic mark has been ascribed to the Ten Eleven Translocation (TET) enzyme. Here, we re-evaluated 6mA presence and TET impact on drosophila genome. Using axenic or conventional breeding conditions, we found only traces of 6mA by LC-MS/MS and no significant increase in 6mA levels in the absence of TET. Further molecular and genetic analyses suggest that TET does not demethylate 6mA but acts essentially in an enzymatic-independent manner. Our results call for further caution concerning the role and regulation of 6mA DNA modification in metazoans.
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
Authors: Currie Michael J. , Davies James S. , Scalise Mariafrancesca , Gulati Ashutosh , Wright Joshua D. , Newton-Vesty Michael C. , Abeysekera Gayan S. , Subramanian Ramaswamy , Wahlgren Weixiao Y. , Friemann Rosmarie , Allison Jane R. , Mace Peter D. , Griffin Michael D.W. , Demeler Borries , Wakatsuki Soichi , Drew David , Indiveri Cesare , Dobson Renwick C.J. , North Rachel A.
Published: October 2023

Tripartite ATP-independent periplasmic (TRAP) transporters are secondary-active transporters that receive their substrates via a soluble binding protein to move bioorganic acids across bacterial or archaeal cell membranes. Recent cryo-EM structures of TRAP transporters provide a broad framework to understand how they work, but the mechanistic details of transport are not yet defined. Here we report the cryo-EM structure of the
Haemophilus influenzae N
-acetylneuraminate TRAP transporter (
Hi
SiaQM) at 2.99 Å resolution (extending to 2.2 Å at the core), revealing new features. The improved resolution (the previous
Hi
SiaQM structure is 4.7 Å resolution) permits accurate assignment of two Na
+
sites and the architecture of the substrate binding site, consistent with mutagenic and functional data. Moreover, rather than a monomer, the
Hi
SiaQM structure is a homodimer. We observe lipids at the dimer interface, as well as a lipid trapped within the fusion that links the SiaQ and SiaM subunits. We show that the affinity (
K
D
) for the complex between the soluble
Hi
SiaP protein and
Hi
SiaQM is in the micromolar range and that a related SiaP can bind
Hi
SiaQM, highlighting features of the complex interface. This work provides key data that enhances our understanding of the ‘elevator-with-an-operator’ mechanism of TRAP transporters.
Representaciones sociales sobre la experiencia de elaborar pósteres académicos: el caso de estudiantes de Ingeniería Electrónica en un curso de escritura
Authors:   Pontificia Universidad Católica del Perú, Tavera Elizabeth , Gamarra Ruiz Marlon M. ,   Pontificia Universidad Católica del Perú, Vásquez Pacheco Víctor ,   Pontificia Universidad Católica del Perú, Alatrista Rocío ,   Pontificia Universidad Católica del Perú
Published: October 2023

Esta investigación busca comprender las representaciones sociales (RS) sobre el proceso de construir y socializar un póster por parte de un grupo de estudiantes de Ingeniería Electrónica que se encuentra en la última etapa de formación universitaria. La metodología adoptó un enfoque cualitativo, de carácter descriptivo-interpretativo y transversal. Como técnica de análisis, se siguieron las orientaciones de la teoría fundamentada (TF). Los resultados del estudio muestran una representación central de la producción y socialización del póster como un conjunto de tareas complejas y muy exigentes, cuya elaboración demanda habilidades lingüístico-cognitivas y sociales, así como destrezas multimodales para las que los alumnos no han sido suficientemente preparados. Asimismo, se concibe la elaboración y socialización de pósteres como una experiencia que genera efectos epistémicos, emocionales y crítico-reflexivos.
Productivity of Dry Grains of Cowpea [Vigna unguiculata (L.)] Creole Cultivar (Canupum), as a Function of Different Planting Densities
Authors: Alves Natalia Fernandes de Oliveira , Linhares Paulo César Ferreira , Sousa Vitória Eduarda de , Carlos Karen Geovana da Silva , Santos Mateus de Freitas Almeida dos , Peixôto Letícia Samilly de Lima , Lobato Lucas Vinicius Cunha , Leite Isaque de Oliveira , Paiva Marynara Rita da Silva , Assis Janilson Pinheiro de , Rodrigues Walter Martins , Lima Isaac Reinaldo Pinheiro de
Published: October 2023

Aims: Cowpea [Vigna unguiculata (L.)] is a legume of great importance, being a source of food rich in protein, being essential for human nutrition and produced during the rainy season in the semi-arid region of Brazil. In this sense, the objective was to study the efficiency of different planting densities on cowpea productivity in the Brazilian semi-arid region.

Place of Study: The experiment was conducted from September to December 2021 at the Rafael Fernandes experimental farm, in the district of Alagoinha (5º03'37 "S, 37º23'50" W), northwest of Mossoró, State of Rio Grande do Norte, Brazil,

 Study Design and Methodology: The experimental design used was randomized complete blocks with five treatments (1.0; 2.0; 3.0, 4.0 and 5.0 plants hole-1) with four replications. Each plot consisted of dimensions of 3.5 m x 4.8 m, with six rows of 4.8 m in length, with a total area of 18.2 m2, with the useful area being the four central rows, with dimensions of 2.8 x 4.8 m, with an area of 13.44 m2, for collecting dry grains.

Agronomic Characteristics of Cowpea [Vigna unguiculata (L.)]: Number of pods, expressed in units ha-1 (NV), length of pods, expressed in cm (CPV), weight of one hundred grains, expressed in grams (P100G), dry grain productivity, expressed in kg ha-1 (PG), number of grains pod-1, expressed in units (GV), dry grain index, expressed in percentage (IGS) and pod production, expressed in grams (PV) of cowpea, Creole cultivar (canapum).

Conclusions: The highest grain productivity was influenced by planting densities, with the density of 3.4 plants per pit being the one that resulted in the highest productivity (409.78 kg ha-1). For the characteristic weight of 100 dry grains, the density of one plant per hole was the one that promoted the highest average weight with a maximum value of 28.24 g.

For farmers who cultivate in a family farming system, a planting density of three plants per hole is recommended.
Neuroprotective Activity of Catharanthus roseus Ethanol Extract by Acetylcholinesterase Inhibition and Neurite Outgrowth Studies
Authors: Doan Nguyet Thi , Nguyen Duong Hoang , Nguyen Tru Van
Published: October 2023

Aims: To investigate biological activities for neuroprotective effect of Catharanthus roseus.

Methodology: Catharanthus roseus was identified using DNA barcoding, utilizing matK, trnH-psbA, and rbcL markers. Additionally, thin-layer chromatography (TLC) method was used to analyze the phytochemistry compounds present in the C. roseus extracts. Moreover, acetylcholinesterase (AChE) inhibition activity was tested using a modified Ellman’s method. Finally, neurite outgrowth activity was determined in rat glial C6 cells treated with varying concentrations of C. roseus extracts.

Results: Overall, the plant samples which were collected in Laocai, Vietnam were successfully identified through DNA barcoding regions, using trnH-psbA, matK, and rbcL genes. Phytochemical analysis detected the presence of sterols, terpenoids, flavonoids, polyphenolic in the ethanol extract and its fraction from C. roseus. Additionally, the extracts of C. roseus displayed remarkably high acetylcholinesterase inhibitory activity. Moreover, the ethanol extract of C. roseus shown the most potent neurotrophic activity in a preliminary cell-based screening based on C6 cells neurite outgrowth.

Conclusion: These results demonstrate that Catharanthus roseus could be a strong candidate for developing pharmacological drugs to treat neurodegenerative diseases.
CRISTIANISMO E GÊNERO
Authors: Silveira Ronie
Published: October 2023

O artigo se propõe a analisar as relações culturais existentes entre o Cristianismo e as questões de gênero no ambiente contemporâneo. Para isso, sua perspectiva se desgarra de pontos de vista religiosos e teológicos, considerando a dinâmica cultural dessa religião no ocidente. O que se verifica, então, é que não há incompatibilidade entre o dispositivo cristão da integração subordinada da pessoa com a ampliação da liberdade ao âmbito da sexualidade. Mais precisamente, a liberdade sexual contemporânea adquire seu sentido como um caso particular da liberdade cristã. A liberdade sexual é completamente cristã.
DELEGACIAS ESPECIALIZADAS DE ATENDIMENTO ÀS MULHERES EM SITUAÇÃO DE VIOLÊNCIA EM SALVADOR (BAHIA, BRASIL): LOCALIZAÇÃO, ÁREAS DE CORBERTURA E ACESSIBILIDADE
Authors: Moreno Marcos
Published: October 2023

Este artigo apresenta os resultados da pesquisa que identifica e analisa a localização, as áreas de cobertura e a acessibilidade das duas Delegacias Especializadas de Atendimento às Mulheres (DEAMs) instaladas no município de Salvador (Bahia, Brasil), tendo como corte temporal o ano 2020 (que marcou o início da pandemia por Covid-19). Metodologicamente, foram indagadas distintas fontes de informação documental para responder a questões-chave sobre o local onde estão instaladas as infraestruturas físicas em que se realizam os atendimentos e sobre as áreas da cidade que são cobertas pelo serviço (encontrando-se este fator inerentemente associado às condições de acessibilidade). No enquadramento analítico considerou-se que tais elementos são centrais na política pública, pois podem incidir na decisão de mulheres em situação de violência de procurar (ou deixar de procurar) ajuda nesse serviço especializado. Os resultados mostram uma invisibilização (sistemática e persistente ao longo do tempo) das informações e dados que justifiquem as decisões do governo do Estado no que diz respeito à suas escolhas geográficas na instalação das DEAMs e na definição das suas áreas de atuação, fragilizando com isso a qualidade do serviço.
HISTÓRIAS SÁFICAS NÃO CONTADAS: UM RECORTE NAS SUBJETIVIDADES LÉSBICAS AFETADAS POR PRODUÇÕES NARRATIVAS
Authors: Ferreira Ariane Corrêa , Bruhn Marília Meneghetti
Published: October 2023

Ao longo da existência do entretenimento, a vivência humana é representada de forma similar à vida real para divertir e emocionar os espectadores. Entretanto, no caso de mulheres lésbicas, a mídia acaba as retratando de forma estereotipada, atribuindo-as frequentemente um final trágico de solidão, conversão ou suicídio. O objetivo desta pesquisa é analisar como essas narrativas hegemônicas impactam nas produções de subjetividades lésbicas. Essa pesquisa qualitativa utiliza-se de uma metodologia cartográfica, na qual rodas de conversa com mulheres lésbicas são registradas em diário de campo. Por fim, o estudo indica que as representações midiáticas afetam a percepção de lésbicas sobre si mesmas, patologizando suas subjetividades e contribuindo para a negação da própria orientação sexual.
Gender Gap in Leadership of Clinical Trials
Authors: Waldhorn Ithai , Bomze David , Ben-Aharon Irit , Schlosser Shir , Markel Gal , Ludmir Ethan B. , Meirson Tomer
Published: October 2023

This cross-sectional study investigates representation of women as principal investigators of clinical trials by study phase, medical specialty, and representation of women trial participants.
Selfie-Induced Diagnostic Challenge in Horner Syndrome
Authors: Castro Luis F. , Butman John A. , Chittiboina Prashant
Published: October 2023

This case report describes an 18-year-old woman with neurofibromatosis type 1 and prior right brachial plexus neurofibroma resection who reported intermittent, unilateral facial flushing after exertion.
Antiplatelets Are Enough for Nondisabling Strokes
Authors: Braksick Sherri A. , Rabinstein Alejandro A.
Published: October 2023

This Viewpoint argues, in keeping with current stroke management guidelines, that patients with mild, nondisabling strokes should not receive thrombolysis, even when presenting within the time window for treatment.
Desulfurivibrionaceae
Authors: Sorokin Dimitry Y. , Merkel Alexander Y.
Published: October 2023

De.sul.fu.ri.vi.bri.o.na.ce'ae. N.L. masc. n.
Desulfurivibrio
, type genus of the family; L. fem. pl. n. suff.
‐aceae
, ending to denote a family; N.L. fem. pl. n.
Desulfurivibrionaceae
, the family of the genus
Desulfurivibrio
.

Thermodesulfobacteria / Desulfobulbia / Desulfobulbales / Desulfurivibrionaceae

The family
Desulfurivibrionaceae
includes obligately anaerobic, moderately salt‐tolerant, and obligately alkaliphilic chemolithoautotrophic bacteria with a unique energy metabolism consisting of elemental sulfur disproportionation. H
2
or formate can also serve as additional electron donors for sulfur reduction, while nitrate can be ammonified with either sulfide or formate as the electron donors. The cultured representatives are found exclusively in saline soda lakes. The family consists of a single genus
Desulfurivibrio
with the type species
D. alkaliphilus
and a second yet undescribed species “
D. dismutans
.”

DNA G
 + 
C content (mol%)
: 60.0–60.3 (whole‐genome sequences).

Type genus
:
Desulfurivibrio
Sorokin et al. 2008, VL123.
Natranaerovirga
Authors: Sorokin Dimitry Y. , Merkel Alexander Y.
Published: October 2023

Na.tra.nae.ro.vir.ga. N.L. neut. n.
natron
, soda (sodium carbonate) (derived from Arabic natrun); Gr. pref.
an‐
, not (here: inseparable prefix); Gr. masc. n.
aêr (gen. aeros)
, air; L. fem. n.
virga
, rod; N.L. fem. n.
Natranaerovirga
, an anaerobic rod living in soda.

Firmicutes A / Clostridia / “Lachnospirales” / “Natranaerovirgaceae” / Natranaerovirga

The genus
Natranaerovirga
is a member of the class
Clostridia
. It includes obligately anaerobic, fermentative heterotrophs whose key metabolic property is the ability to utilize polygalacturonates as growth substrates. The species of the genus are highly salt tolerant, chloride independent, and obligate alkaliphiles found in saline soda lakes and soils in Central Asia. The genus currently includes two species:
Natranaerovirga pectinivora
, the type species of the genus, and
Natranaerovirga hydrolytica
.

DNA G
 + 
C content (mol%)
: 31.3–32.3 (whole‐genome sequences).

Type species
:
Natranaerovirga pectinivora
Sorokin et al. 2012, VL145.
Pluralibacter
Authors: Brady Carrie L.
Published: October 2023

Plu.ra.li.bac'ter. L. masc./fem. adj.
pluralis
, belonging or relating to more than one, relating to many; N.L. masc. n.
bacter
, equivalent of bacterium, a small rod; N.L. masc. n.
Pluralibacter
, a bacteria (rod) from many sources.

Proteobacteria / Gammaproteobacteria / Enterobacterales / Enterobacteriaceae / Pluralibacter

Pluralibacter
species are regularly isolated from clinical samples, cosmetics, environmental sources including water, and vegetables and cereals as well as pear trees suffering from brown leaf spot disease. Cells are Gram‐stain‐negative, facultatively anaerobic, and motile rods. Species are mesophilic, favoring growth temperatures of 30–36°C. Carbon sources such as glucose,
l
‐arabinose, cellobiose, fructose, galactose, maltose, β‐methyl‐
d
‐glucoside,
d
‐mannitol, mannose,
N
‐acetylglucosamine, and
N
‐acetylgalactosamine are readily assimilated. Species form a monophyletic clade when phylogenetic analysis is based on multilocus sequence analysis (MLSA) or whole‐genome sequences. The major fatty acids are C
14:0
, C
16:0
, C
17:0
cyclo, and C
18:1
ω7
c
.

DNA G + C content (mol%)
: 57.0–60.0 (
T
m
).

Type species
:
Pluralibacter gergoviae
Brady et al. 2013, VL154 (Brenner et al. 1980).
Intrinsic Highly Conductive and Mechanically Robust Li‐Rich Cathode Materials Enabled by Microstructure Engineering for Enhanced Electrochemical Properties
Authors: Liu Yuanyuan , Zhang Chenying , Lin Liang , Ai Xin , Gui Siwei , Guo Weibin , Li Saichao , Wang Laisen , Yang Hui , Peng Dong‐Liang , Xie Qingshui
Published: October 2023

Li‐rich Mn‐based layered oxides (LRLO) are considered promising cathode candidates for high‐energy‐density lithium‐ion batteries (LIBs). However, severe capacity/voltage fading and poor rate performance hinder their practical application. Herein, a microstructure engineering strategy is put forward to design the unique bayberry‐like Li1.2Mn0.54Co0.13Ni0.13O2 (LRLO‐S) cathode material, composed of a spherical core and the shell self‐assembled by radially oriented nanorods with intrinsic rapid electron and ion transport capability, benefiting to increase the electrochemical reaction kinetics during cycling. Meanwhile, the radial texturing of the nanorods in shell layer forms a natural protective interface constituted by thermodynamically stable (003) planes, resisting electrolyte corrosion effectively. Furthermore, the configuration of orderly self‐assembled nanorods can effectively regulate the stress and strain to stabilize the lattice framework, finally improves the cycling stability of LRLO. As a result, the elaborately designed LRLO‐S cathode delivers remarkable high‐rate long‐term cycling stability with high capacity retentions of 91.2% after 500 cycles at 1 C and of 81.3% after 1000 cycles at 5 C. More importantly, the voltage stability is enhanced greatly with a superior retention of 89.6% after cycling 500 times at 1 C. Here a valuable strategy is provided to develop intrinsic mechanically robust high‐performance Li‐rich‐layered cathode materials for advanced LIBs.
Optically Active A‐Shaped Cyclic Molecules Based on Planar Chiral [2.2]Paracyclophanes Emitting Bright Circularly Polarized Luminescence with High Anisotropy Factors
Authors: Matsumura Kensei , Inoue Ryo , Morisaki Yasuhiro
Published: October 2023

Optically active A‐shaped cyclic molecules are synthesized by incorporating a planar chiral [2.2]paracyclophane unit to form a helical structure. These molecules exhibit large molar absorption coefficients, moderate photoluminescence (PL) quantum efficiencies, and high circularly polarized luminescence (CPL) anisotropy factors, resulting in high CPL brightness values (BCPL values). According to the time‐dependent density functional theory (TD‐DFT) theoretical studies, extended π‐conjugated moieties act as light‐harvesting units, and emissions occur from the helical skeletons. The TD‐DFT calculations reproduce the experimentally determined absorption, PL, circular dichroism, and CPL properties of the A‐shaped cyclic molecules.
A Glutathione Peroxidase‐Mimicking Nanozyme Precisely Alleviates Reactive Oxygen Species and Promotes Periodontal Bone Regeneration
Authors: Zhu Bijun , Wu Jiangjiexing , Li Tong , Liu Songtao , Guo Junheng , Yu Yijun , Qiu Xinyi , Zhao Yue , Peng Haoran , Zhang Jinli , Miao Leiying , Wei Hui
Published: October 2023

The use of oxidoreductase nanozymes to regulate reactive oxygen species (ROS) has gradually emerged in periodontology treatments. However, current nanozymes for treating periodontitis eliminate ROS extensively and non‐specifically, ignoring the physiological functions of ROS under normal conditions, which may result in uncontrolled side effects. Herein, using the MIL‐47(V)‐F (MVF) nanozyme, which mimics the function of glutathione peroxidase (GPx), it is proposed that ROS can be properly regulated by specifically eliminating H2O2, the most prominent ROS. Through H2O2 elimination, MVF contributes to limiting inflammation, regulating immune microenvironment, and promoting periodontal regeneration. Moreover, MVF stimulates osteogenic differentiation of periodontal stem cells directly, further promoting regeneration due to the vanadium in MVF. Mechanistically, MVF regulates ROS by activating the nuclear factor erythroid 2‐related factor 2/heme oxygenase 1 (Nrf2/HO‐1) pathway and promotes osteogenic differentiation directly through the phosphatidylinositol 3‐kinase/protein kinase B (PI3K/Akt) pathway. A promising periodontitis therapy strategy is presented using GPx‐mimicking nanozymes through their triple effects of antioxidation, immunomodulation, and bone remodeling regulation, making nanozymes an excellent tool for developing precision medicine.
Labile Coordination Interphase for Regulating Lean Ion Dynamics in Reversible Zn Batteries
Authors: Wang Chenxiang , Zhu Jason Zi Jie , Vi‐Tang Samantha , Peng Bosi , Ni Chenhao , Li Qizhou , Chang Xueying , Huang Ailun , Yang Zhiyin , Savage Ethan J. , Uemura Sophia , Katsuyama Yuto , El‐Kady Maher F. , Kaner Richard B.
Published: October 2023

Rechargeability in zinc (Zn) batteries is limited by anode irreversibility. The practical lean electrolytes exacerbate the issue, compromising the cost benefits of zinc batteries for large‐scale energy storage. In this study, a zinc‐coordinated interphase is developed to avoid chemical corrosion and stabilize zinc anodes. The interphase promotes Zn2+ ions to selectively bind with histidine and carboxylate ligands, creating a coordination environment with high affinity and fast diffusion due to thermodynamic stability and kinetic lability. Experiments and simulations indicate that interphase regulates dendrite‐free electrodeposition and reduces side reactions. Implementing such labile coordination interphase results in increased cycling at 20 mA cm−2 and high reversibility of dendrite‐free zinc plating/stripping for over 200 hours. A Zn||LiMn2O4 cell with 74.7 mWh g−1 energy density and 99.7% Coulombic efficiency after 500 cycles realized enhanced reversibility using the labile coordination interphase. A lean‐electrolyte full cell using only 10 µL mAh−1 electrolyte is also demonstrated with an elongated lifespan of 100 cycles, five times longer than bare Zn anodes. The cell offers a higher energy density than most existing aqueous batteries. This study presents a proof‐of‐concept design for low‐electrolyte, high‐energy‐density batteries by modulating coordination interphases on Zn anodes.
Sugar‐Derived Nanocrystalline Graphite Matrix C/C Composites with Excellent Ablative Resistance at 3000 °C
Authors: Zhang Wenzheng , Tan Mingyi , Chen Daming , Sun Boqian , Cheng Yuan , Xun Liancai , Hu Jingsheng , Hou Chenlin , Liu Yuxuan , Fang Yuhao , Hu Ping , Han Wenbo , Dong Shun , Du Shanyi , Han Jiecai , Miao Shuxi , Yang Qidong , Zhou Yanchun , Zhang Xinghong
Published: October 2023

Sugars are renewable resources essential to human life, but they are rarely used as raw materials for the industrial production of carbon‐based materials, especially for the preparation of carbon fiber‐reinforced carbon‐matrix (C/C) composites, which are extremely useful for the semiconductor and aerospace sectors. Herein, a method utilizing sugar‐derived carbon to replace petrochemicals as dense matrix to preparing C/C composites is reported. The matrix from sugar‐derived C/C (S–C/C) composites has a nanocrystalline graphite structure that is highly thermally stable and effectively bonded to the carbon fibers. The mechanical properties of the S–C/C composite are comparable to those prepared from petrochemical sources; significantly, it exhibits a linear ablation rate of 0.03 mm s−1 after 200 s of ablation at 3000 °C in 10 MW m−2 heat flux. This new class of S–C/C is promising for use in a broad range of fields, ranging from semiconductor to aerospace.
Broadband Microelectromechanical Systems‐Based Silicon Nitride Photonic Switch
Authors: Swain Shubhashree , Zawierta Michal , Gurusamy Jega , Martyniuk Mariusz , Keating Adrian , Putrino Gino , Faraone Lorenzo , Silva Dilusha
Published: October 2023

Over the past three decades, silicon photonic devices have been core to the realization of large‐scale photonic‐integrated circuits. However, silicon nitride is another key complementary metal oxide semiconductor‐compatible material for high‐density photonic‐integrated circuits, having low manufacturing costs, low optical losses, and excellent mechanical properties, that can provide enhanced performance over silicon in an integrated photonic platform. This article presents the design, fabrication, and testing of a proof‐of‐concept switchable silicon nitride photonic coupler that leverages these properties combined with microelectromechanical systems actuation. The photonic platform uses a moveable suspended waveguide to enable efficient out‐of‐plane switching and is built using conventional lithographic techniques to demonstrate the high compatibility with existing microelectronic fabrication techniques. The photonic switch is measured to have an insertion loss of 2.6 dB and an ON/OFF extinction ratio of 34 dB at the output of the suspended waveguide, at a wavelength of 1470 nm. Detailed simulations demonstrate broadband operation over a 600 nm wavelength range from 1.25 to 1.85 μm which is experimentally validated over the range from 1.25 to 1.61 μm. To the best of knowledge, this is the broadest operation range ever demonstrated by a photonic switch in simulation.
Base‐Promoted Synthesis of N−H Free Pyrroles via net [3+2]‐Cycloaddition
Authors: Jin Huimin , Zhou Fan , Xiang Zhenhua , Chen Lingfeng , Liang Guang , Walsh Patrick J. , Li Jie
Published: October 2023

A base‐promoted net‐[3+2] cycloaddition of nitriles and 1‐arylpropynes for the synthesis of pyrroles is described. The developed method provides convenient access to various 2,5‐disubstituted or 2,4,5‐trisubstituted pyrroles in 40% to 96% yields (32 examples). Among methods for the synthesis of pyrroles, the protocol presented here stands out for its convenience and atom‐economy.
Mitigating Intrinsic Interfacial Degradation in Semi‐Transparent Perovskite Solar Cells for High Efficiency and Long‐Term Stability
Authors: Naqvi Syed Dildar Haider , Son Kyungnan , Jung Wonzee , Hwang Hui ung , Lee Sangmin , Lee Arheum , Keum Minjong , Kim Sunwook , Kim Jeong Won , Kang Min Gu , Song Hee‐eun , Hong Sungjun , Jeong Inyoung , Ahn Seungkyu , Lambertz Andreas , Ding Kaining , Duan Weiyuan , Yim Kanghoon , Ahn SeJin
Published: October 2023

Conventional semi‐transparent perovskite solar cells (ST‐PSCs) generally exhibit inferior performance and stability relative to opaque PSCs. However, a comprehensive understanding of the origins of inferior performance and stability of ST‐PSCs and a practical solution to these challenges are both lacking. Here, it is shown for the first time that lithium ions from a lithium bis(trifluoromethanesulfonyl)imide (LiTFSI)‐doped 2,2′,7,7′‐tetrakis[N,N‐di(4‐methoxyphenyl)amino]−9,9′‐spirobifluorene (Spiro‐MeOTAD) hole‐transport layer (HTL) can diffuse into the molybdenum trioxide buffer layer at their interface, yielding ST‐PSCs with lower efficiency and accelerated degradation. It is also demonstrated that this undesired Li‐ion diffusion can be avoided by HTL surface modification with stable lithium oxides. Using this approach, the constructed ST‐PSC exhibits a new record power conversion efficiency (PCE) of 22.02% (21.68% certified) and a fill factor of >80%, with >99% shelf‐stability after 400 h and >99% operational stability for 240 h, which clears away this longstanding limitation of the performance and stability of ST‐PSCs. This strategy is also applied to fabricate four‐ and two‐terminal perovskite/silicon tandem solar cells with bifacial equivalent efficiencies of 31.5% and 26.34%, respectively, at 20% albedo.