bluuebunny/crossref_metadata_2025 huggingface dataset:
CFO overconfidence and conditional accounting conservatism
Authors: Qiao Lu , Adegbite Emmanuel , Nguyen Tam Huy
Published: November 2023

This study investigates the association between Chief Financial Officers (CFOs) overconfidence and conditional accounting conservatism. Relying on upper echelons and overconfidence theories and based on a large sample of US-listed firms’ data from 1992 to 2019 (21,626 firm-year observations), we find a statistically and economically significant negative relationship between CFO overconfidence and conditional accounting conservatism, suggesting that overconfident CFOs tend to diminish conditional accounting conservatism. These findings persist in a series of robustness tests. In the mechanism analysis, we predict that overconfident CFOs aim to convey private information by reducing conditional accounting conservatism. We prove this conjecture by observing that overconfident CFOs who adopt lower levels of conditional accounting conservatism increase earnings informativeness (i.e., the amount of information about future cash flows or earnings contained in current stock returns) and reduce their precautionary incentives to save cash. We further rule out another mechanism (i.e. compensation concerns) that may motivate overconfident CFOs to reduce conditional accounting conservatism. Moreover, we show that overconfident CFOs with higher powers are more able to minimize conditional accounting conservatism. Our study highlights the significance and motivation of overconfident CFOs in determining asymmetric recognition of good and bad news.
Celebrating Differences: A Conjoint Analysis of Senior Year Mechanical Engineering Students’ Occupational Preferences
Authors: Magarian James N. , Seering Warren P.
Published: November 2023

Given its ongoing struggles at attaining demographic diversity and its key role in nations’ economies, the engineering workforce receives considerable attention from researchers and policymakers. Yet, prior studies and STEM recruitment initiatives have often underemphasized the variety among available engineering jobs and careers. It therefore remains unclear which attributes of engineering work are most salient in shaping students’ choices to persist in or depart from engineering pathways. This study introduces a novel conjoint survey experiment conducted with over 1000 senior year mechanical engineering students. This randomized experiment allows the authors to disentangle supply-side and demand-side factors to assess engineering job attributes’ marginal influences on students’ occupational preferences, as well as to examine these attributes’ interaction effects with supply-side factors. Toward strengthening persistence in engineering pathways, findings suggest that broad STEM recruitment initiatives, though potentially advantageous in pre-college years, should give way to more targeted campaigns that increase university students’ awareness about key dimensions of variety across engineering work roles.
Do Virtual Environments Close the Gender Gap in Participation in Question-and-Answer Sessions at Academic Conferences? In Search of Moderation by Conference Format
Authors: Jarvis Shoshana N. , Nguyen Christine Q. , Zhu Minwan , Ebersole Charles R. , Kray Laura J.
Published: November 2023

Consistent with power and status differences between men and women in society, men tend to participate more than women do in question-and-answer (Q&A) sessions at in-person academic conferences. This gap in participation in scientific discourse may perpetuate the status quo. The current research examines whether this gender gap in participation in Q&A sessions extends to virtual conferences, which have become more prevalent during the COVID-19 pandemic. Due to shifts in conference formats to enable asynchronous, anonymous, and/or simultaneous participation, we examined whether virtual conferences are more inclusive, and mitigate the gender gap in Q&A participation. Across four virtual conferences that varied in gender representation and Q&A structured format, men continued to take a disproportionate amount of time and space in Q&A sessions. Disproportionate participation did not significantly vary between in-person and virtual formats and did not systematically vary by how the Q&A session was organized. In an all-chat virtual conference, gender differences in volubility were attenuated among higher status academics. Gendered participation and volubility were also impacted by which sub-discipline the presentation was in. Discussion considers the theoretical and practical implications of these findings for understanding the persistence of gender inequality in science. We encourage future research that attends to the cultural factors that promote or mitigate gender disparities in participation.
Mesoglycan for the secondary prevention of superficial vein thrombosis: a randomized, controlled, double-blind study (METRO Study)—rationale and protocol
Authors: Camporese G. , Bernardi E. , Bortoluzzi C. , Noventa F. , Simioni P. ,   for the METRO Investigator Study Group
Published: November 2023

No data is available about pharmacological secondary prevention of superficial vein thrombosis (SVT) despite 10–15% of patients develop venous thromboembolic complications at 3–6 months after an adequate treatment of the acute phase. To verify efficacy and safety of mesoglycan in secondary prevention of SVT recurrence and venous thromboembolic complications. Phase III multicenter, double-blind, randomized, superiority trial comparing mesoglycan 50 mg bid vs placebo in consecutive patients with a SVT extended at least 5 cm, after the initial 45-day treatment course with fondaparinux 2.5 mg once-daily. Primary efficacy outcome: SVT recurrence/extension, symptomatic venous thromboembolism (VTE), asymptomatic proximal deep-vein thrombosis, death. Primary safety outcome: major bleeding. We hypothesized a 12-month 15% incidence of the primary efficacy outcome in placebo group and a 50% risk reduction in mesoglycan group. A bilateral log-rank test with a sample of 650 patients (randomization 1:1) reach a 90% power, with an α-error of 0.025, of detecting a 7.0% difference (HR = 0.51) after 12 months of treatment, considering a 10% patients drop-out. At deadline (December 31, 2022) 570 patients have been randomized (10% drop rate). Mean age was 63.9 years, 58.8% were women. SVT involved great saphenous vein in 69.3%, small saphenous vein in 13.1%, and collaterals in 17.6% of patients. SVT was the first event in 61.7%, a recurrence in 38.3%, provoked in 50.2% and unprovoked in 49.8%. Patients not experiencing a primary outcome, or not retiring their consent will be followed up to December 31, 2024 when the final data analysis will be performed

ClinicalTrials.gov: NCT03428711.
Concurrent hypoglossal and phrenic nerve stimulation in patients with obstructive and treatment emergent central sleep apnea
Authors: Steffen Armin , Schöbel Christoph , Vogler Julia , Bruchhage Karl-Ludwig , Tilz Roland Richard
Published: November 2023

Background

Patients with obstructive or central sleep apnea are primarily treated with positive airway pressure treatment. There are novel implantable options targeting either obstructive sleep apnea using hypoglossal nerve stimulation (HNS) or central sleep apnea using phrenic nerve stimulation (PNS).

Methods

Patients with sleep apnea were implanted with both HNS and PNS devices, and their response to each therapy was monitored using home sleep tests as well as Epworth Sleepiness scale (ESS).

Results

We evaluated our concurrent neurostimulation approach in two patients. Both patients were implanted with two neuromodulation devices: The first case suffered from treatment emergent central sleep apnea after HNS activation for primarily obstructive sleep apnea (apnea–hypopnea index/AHI 54/h). The central portion resolved under PNS (AHI 23.7/h). The second case suffered from predominantly central sleep apnea (AHI 82/h). Here, the PNS device was implanted first, resulting in a subsequent reduction of the central portion. The residual obstructive sleep apnea was addressed using HNS (AHI 5.4/h). No interaction between the HNS and PNS systems was noticed in either of the two patients.

Conclusions

In selected cases, a concurrent treatment with hypoglossal and phrenic nerve stimulation may lead to improvement of sleep apnea and patient satisfaction in a safe manner.
Acute cerebellitis following COVID-19 infection associated with autoantibodies to glutamate receptors: a case report
Authors: Watanabe Takuya , Kakinuma Yuki , Watanabe Keiko , Kinno Ryuta
Published: November 2023

While COVID-19 infection by the SARS-CoV-2 virus was initially identified as a respiratory disease, mounting evidence suggests its association with various neurological issues as well. Notably, COVID-19 has been linked to acute cerebellitis (AC) and post-infectious cerebellar ataxia. The precise underlying mechanisms behind these neurological effects remain unclear. Our case report describes AC following COVID-19 infection, associated with autoantibodies to glutamate receptors (GluRs), hinting at immunological involvement. The case is a 56-year-old woman who experienced fever and fatigue due to COVID-19 infection. About 2 weeks after these symptoms improved, she showed cerebellar symptoms such as ocular overshoot and ataxia when presenting to our hospital. Her cerebrospinal fluid (CSF) findings were normal. Brain MRI revealed cerebellar abnormalities. Treatment with methylprednisolone led to symptom improvement. Later tests of CSF yielded positive results for autoantibodies to GluRs. Our findings suggest a possible immune-mediated mechanism in the onset of AC following COVID-19 infection. Clinicians should consider the possibility of immunological pathogenesis when diagnosing cerebellar symptoms after COVID-19 infection.
RETRACTED ARTICLE: Unmanned Vehicle Fusion Positioning Technology Based on “5G + Beidou” and 3D Point Cloud Image
Authors: Fu Siyong , Zhao Qinghua , Fan Zhen , Tao Qiuxiang , Liu Hesheng
Published: November 2023

Unmanned vehicles need to know their location and direction information accurately to plan and navigate their paths. However, the positioning system is susceptible to interference from a variety of factors, which leads to increased positioning errors, thereby affecting the accuracy of unmanned vehicle positioning. An unmanned vehicle fusion positioning technology based on the "5G + Beidou" integrated positioning system was proposed. While using the "5G + Beidou" base station for positioning, the 3D point cloud image was fused, and the high-precision real-time positioning was carried out through the vehicle's autonomous navigation algorithm. This paper first analyzed the current situation and characteristics of GNSS technology and studied the key technologies and principles of the "5G + Beidou" integrated positioning system. Then, aiming at the difficulty of 5G base station deployment, the GNSS system parameter optimization scheme based on a multidimensional fusion structure was designed. Finally, in the experiment, it was verified that the fusion system could achieve higher precision positioning results compared with traditional single-dimensional GNSS and multi-dimensional GNSS. The technical advantages of "5G + Beidou" were used for data fusion processing of unmanned vehicles, and a positioning method based on the combination of 3D point cloud image and high-precision map was proposed. Through some experiments, it was concluded that the fusion location method could control the error below 0.1, which showed the accuracy of the fusion location.
The Trial Innovation Network Liaison Team: building a national clinical and translational community of practice
Authors: Palm Marisha E. , Thompson Dixie D. , Edwards Terri , Swartz Kitt , Herzog Keith A. , Bansal Shweta , Echalier Benjamin , DeHart Kristen Clasen , Denmark Signe , Wilson Jurran L. , Nelson Sarah , Waddy Salina P. , Dunsmore Sarah E. , Atkinson Jane C. , Wiley Ken , Hassani Sara , Dwyer Jamie P. , Hanley Daniel F. , Dean J. Michael , Ford Daniel E.
Published: November 2023

In 2016, the National Center for Advancing Translational Science launched the Trial Innovation Network (TIN) to address barriers to efficient and informative multicenter trials. The TIN provides a national platform, working in partnership with 60+ Clinical and Translational Science Award (CTSA) hubs across the country to support the design and conduct of successful multicenter trials. A dedicated Hub Liaison Team (HLT) was established within each CTSA to facilitate connection between the hubs and the newly launched Trial and Recruitment Innovation Centers. Each HLT serves as an expert intermediary, connecting CTSA Hub investigators with TIN support, and connecting TIN research teams with potential multicenter trial site investigators. The cross-consortium Liaison Team network was developed during the first TIN funding cycle, and it is now a mature national network at the cutting edge of team science in clinical and translational research. The CTSA-based HLT structures and the external network structure have been developed in collaborative and iterative ways, with methods for shared learning and continuous process improvement. In this paper, we review the structure, function, and development of the Liaison Team network, discuss lessons learned during the first TIN funding cycle, and outline a path toward further network maturity.
Are new digital technologies and social media causing the spike in anxiety and depression in young people?
Authors: Hickie Ian B. , Kay Lambkin Frances , La Sala Louise , Robinson Jo , Iorfino Frank
Published: November 2023

The increasing rates of anxiety, depression and self-harm reported by young people in developed countries over the last decade has led to speculation about the associations between this evidence of deteriorating mental health and wellbeing and the rapid spread and use of new digital technologies, social media and personal messaging platforms (Orben and Przybylski, 2019; Nesi, 2020). It has become commonplace to assert that these rapid technological changes, and their associated adverse impacts on social group function and interpersonal behaviour, are the cause of these fundamental epidemiological shifts.
Peer Versus Pure Benchmarks in the Compensation of Mutual Fund Managers
Authors: Evans Richard , Gómez Juan-Pedro , Ma Linlin , Tang Yuehua
Published: November 2023

We examine the role of peer (e.g., Lipper manager indices) versus pure (e.g., S&P 500) benchmarks in fund manager compensation. We model their impact on manager incentives and then test those predictions using novel data. We find that 71% of managers are compensated based on peer benchmarks. Consistent with the model, peer-benchmarked fund managers exhibit higher effort generating higher gross performance and collect higher fee income. Analyzing advisors’ choice between benchmark types, we show that peer-benchmarking advisors cater to more sophisticated and performance-sensitive investors, and are more likely to sell through direct channels, consistent with investor heterogeneity and market segmentation.
LINEAR GROWTH OF TRANSLATION LENGTHS OF RANDOM ISOMETRIES ON GROMOV HYPERBOLIC SPACES AND TEICHMÜLLER SPACES
Authors: Baik Hyungryul , Choi Inhyeok , Kim Dongryul M.
Published: November 2023

We investigate the translation lengths of group elements that arise in random walks on the isometry groups of Gromov hyperbolic spaces. In particular, without any moment condition, we prove that non-elementary random walks exhibit at least linear growth of translation lengths. As a corollary, almost every random walk on mapping class groups eventually becomes pseudo-Anosov, and almost every random walk on
$\mathrm {Out}(F_n)$
eventually becomes fully irreducible. If the underlying measure further has finite first moment, then the growth rate of translation lengths is equal to the drift, the escape rate of the random walk.

We then apply our technique to investigate the random walks induced by the action of mapping class groups on Teichmüller spaces. In particular, we prove the spectral theorem under finite first moment condition, generalizing a result of Dahmani and Horbez.
Efficient Measurement of Global Human Identification and Citizenship	– Is One Item Sufficient?
Authors: Geisen Philipp , Trutzenberg Friedemann , Eid Michael
Published: November 2023

Abstract: To address the complexity of global challenges (e.g., migration, climate change), research must examine many constructs and their interrelationships. Therefore, efficient assessment methods (e.g., short scales) are required, especially when constructing large-scale social surveys. A widely used instrument for assessing global identification as an important predictor of behavior related to coping with global challenges is the Identification With All Humanity (IWAH) scale ( McFarland et al., 2012 ). With the present study, we aimed to investigate whether this scale can be sufficiently represented by a single item. Using bifactor-(S*I − 1) models, we analyzed whether one item from the scale itself (Item 5) and a related single-item measure from the World Values Survey (WVS; Inglehart et al., 2018 ) could adequately represent a German version of the IWAH scale. The sample ( n = 1,369) was representative of the German population regarding age, gender, income, education, and region of residence. Item 5 showed an appropriate single-item reliability (.82) and represented 64–93% of the true variance in the individual IWAH items, whereas the WVS item (Rel( YWVS) = .61) represented 52–81%. To reflect the multidimensionality of the IWAH, a 4-item short scale is recommended.
Validity of an Inconsistency Scale for the PID-5 in	Community-Dwelling Younger and Older Adults
Authors: Dubois Allyson , Sellbom Martin , Rossi Gina
Published: November 2023

Abstract: The Personality Inventory for DSM-5 (PID-5; Krueger et al., 2012 ) is a self-report questionnaire measuring pathological traits of personality disorders. Keeley and colleagues (2016) developed an Inconsistency Scale for the PID-5 (PID-5-INC) to detect random responses. We examined the ability of the PID-5-INC to detect inconsistent responders in a new linguistic context (Dutch) and age group (older adults). The Dutch PID-5 version ( van der Heijden et al., 2014 ) was administered to two Dutch community-dwelling younger (18–64 years old: N = 439) and older adults (65 years or older: N = 251). The PID-5-INC item pairs showed large interitem correlations in the younger adult sample and at least medium interitem correlations, except for one item pair, in the older adult sample. Similarly to Keeley and colleagues , a cut-off score of 17 was the optimal cut-off point for both the younger and older adult samples. However, for the younger adult sample, a cut-off score of 16 provided an even better balance between specificity and sensitivity. We concluded that our results support the use of the PID-5-INC in Dutch-speaking community-dwelling younger and older adults and point out the importance of including validity scales for self-report questionnaires.
Acidified drinking water improves motor function, prevents tremors and changes disease trajectory in Cln2R207X mice, a model of late infantile Batten disease
Authors: Kovács Attila D. , Gonzalez Hernandez Jose L. , Pearce David A.
Published: November 2023

Batten disease is a group of mostly pediatric neurodegenerative lysosomal storage disorders caused by mutations in the CLN1–14 genes. We have recently shown that acidified drinking water attenuated neuropathological changes and improved motor function in the Cln1R151X and Cln3−/− mouse models of infantile CLN1 and juvenile CLN3 diseases. Here we tested if acidified drinking water has beneficial effects in Cln2R207X mice, a nonsense mutant model of late infantile CLN2 disease. Cln2R207X mice have motor deficits, muscle weakness, develop tremors, and die prematurely between 4 and 6 months of age. Acidified water administered to Cln2R207X male mice from postnatal day 21 significantly improved motor function, restored muscle strength and prevented tremors as measured at 3 months of age. Acidified drinking water also changed disease trajectory, slightly delaying the death of Cln2R207X males and females. The gut microbiota compositions of Cln2R207X and wild-type male mice were markedly different and acidified drinking water significantly altered the gut microbiota of Cln2R207X mice. This suggests that gut bacteria might contribute to the beneficial effects of acidified drinking water. Our study demonstrates that drinking water is a major environmental factor that can alter disease phenotypes and disease progression in rodent disease models.
Engineered CHO cells as a novel AAV production platform for gene therapy delivery
Authors: Nagy Abdou , Chakrabarti Lina , Kurasawa James , Mulagapati Sri Hari Raju , Devine Paul , Therres Jamy , Chen Zhongying , Schmelzer Albert E.
Published: November 2023

The Herpes simplex virus (HSV)-based platform for production of recombinant adeno-associated viral vectors (rAAVs) yields higher titers and increased percentage of full capsids when compared to the triple transient transfection (TTT) method. However, this platform currently faces two major challenges. The first challenge is the reliance on commercial media, sometimes supplemented with serum, leading to costly manufacturing and a high risk for introduction of adventitious agents. The second challenge is that the production of HSV-1 relies on adherent complementing Vero cells (V27), making it difficult to scale up. We engineered serum-free-adapted CHO cells expressing key HSV-1 entry receptors, HVEM and/or Nectin-1 to address the first challenge. Using high-throughput cloning methods, we successfully selected a HVEM receptor-expressing clone (CHO–HV–C1) that yields 1.62 × 109, 2.51 × 109, and 4.07 × 109 viral genome copies/mL with rAAV6.2-GFP, rAAV8-GFP, and rAAV9-GFP vectors respectively, within 24 h post rHSV-1 co-infection. Moreover, CHO–HV–C1-derived rAAVs had comparable in vitro transduction, infectivity, and biodistribution titers to those produced by TTT. The second challenge was addressed via engineering CHO–HV–C1 cells to express HSV-1 CP27. These cells successfully produced rHSV-1 vectors, but with significantly lower titers than V27 cells. Taken together, the CHO/HSV system provides a novel, scalable, reduced cost, serum-free AAV manufacturing platform.
A classification method for soybean leaf diseases based on an improved ConvNeXt model
Authors: Wu Qinghai , Ma Xiao , Liu Haifeng , Bi Cunguang , Yu Helong , Liang Meijing , Zhang Jicheng , Li Qi , Tang You , Ye Guanshi
Published: November 2023

Deep learning technologies have enabled the development of a variety of deep learning models that can be used to detect plant leaf diseases. However, their use in the identification of soybean leaf diseases is currently limited and mostly based on machine learning methods. In this investigation an enhanced deep learning network model was developed to recognize soybean leaf diseases more accurately. The improved network model consists of three parts: feature extraction, attention calculation, and classification. The dataset used was first diversified through data augmentation operations such as random masking to enhance network robustness. An attention module was then used to generate feature maps at various depths. This increased the network’s focus on discriminative features, reduced background noise, and enabled the use of the LeakyReLu activation function in the attention module to prevent situations in which neurons fail to learn when the input is negative. Finally, the extracted features were then integrated using a fully connected layer, and the predicted disease category inferred to improve the classification accuracy of soybean leaf diseases. The average recognition accuracy of the improved network model for soybean leaf diseases was 85.42% both higher than the six deep learning comparison models (ConvNeXt (66.41%), ResNet50 (72.22%), Swin Transformer (77.00%), MobileNetV3 (67.27%), ShuffleNetV2 (59.89%), and SqueezeNet (72.92%)), thus proving the effectiveness of the improved method.The model proposed in this paper was also tested on the grapevine leaf dataset, and the performance ability of the improved network model remained due to other common network models, and overall the proposed network model was very effective in leaf disease identification.
Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury
Authors: Štepánková Kateřina , Chudíčková Milada , Šimková Zuzana , Martinez-Varea Noelia , Kubinová Šárka , Urdzíková Lucia Machová , Jendelová Pavla , Kwok Jessica C. F.
Published: November 2023

Spinal cord injury (SCI) induces the upregulation of chondroitin sulfate proteoglycans (CSPGs) at the glial scar and inhibits neuroregeneration. Under normal physiological condition, CSPGs interact with hyaluronan (HA) and other extracellular matrix on the neuronal surface forming a macromolecular structure called perineuronal nets (PNNs) which regulate neuroplasticity. 4-methylumbelliferone (4-MU) is a known inhibitor for HA synthesis but has not been tested in SCI. We first tested the effect of 4-MU in HA reduction in uninjured rats. After 8 weeks of 4-MU administration at a dose of 1.2 g/kg/day, we have not only observed a reduction of HA in the uninjured spinal cords but also a down-regulation of CS glycosaminoglycans (CS-GAGs). In order to assess the effect of 4-MU in chronic SCI, six weeks after Th8 spinal contusion injury, rats were fed with 4-MU or placebo for 8 weeks in combination with daily treadmill rehabilitation for 16 weeks to promote neuroplasticity. 4-MU treatment reduced the HA synthesis by astrocytes around the lesion site and increased sprouting of 5-hydroxytryptamine fibres into ventral horns. However, the current dose was not sufficient to suppress CS-GAG up-regulation induced by SCI. Further adjustment on the dosage will be required to benefit functional recovery after SCI.
Prognostic value and immune landscapes of immunogenic cell death-associated lncRNAs in lung adenocarcinoma
Authors: Shu Kexin , Cai Chenxi , Chen Wanying , Ding Jiatong , Guo Zishun , Wei Yiping , Zhang Wenxiong
Published: November 2023

Immunogenic cell death (ICD) has been demonstrated to activate T cells to kill tumor cells, which is closely related to tumor development, and long noncoding RNAs (lncRNAs) are also involved. However, it is not known whether ICD-related lncRNAs are associated with the development of lung adenocarcinoma (LUAD). We downloaded ICD-related genes from GeneCards and the transcriptome statistics of LUAD patients from The Cancer Genome Atlas (TCGA) and subsequently developed and verified a predictive model. A successful model was used together with other clinical features to construct a nomogram for predicting patient survival. To further study the mechanism of tumor action and to guide therapy, we performed enrichment analysis, tumor microenvironment analysis, somatic mutation analysis, drug sensitivity analysis and real-time quantitative polymerase chain reaction (RT-qPCR) analysis. Nine ICD-related lncRNAs with significant prognostic relevance were selected for model construction. Survival analysis demonstrated that overall survival was substantially shorter in the high-risk group than in the low-risk group (P < 0.001). This model was predictive of prognosis across all clinical subgroups. Cox regression analysis further supported the independent prediction ability of the model. Ultimately, a nomogram depending on stage and risk score was created and showed a better predictive performance than the nomogram without the risk score. Through enrichment analysis, the enriched pathways in the high-risk group were found to be primarily associated with metabolism and DNA replication. Tumor microenvironment analysis suggested that the immune cell concentration was lower in the high-risk group. Somatic mutation analysis revealed that the high-risk group contained more tumor mutations (P = 0.00018). Tumor immune dysfunction and exclusion scores exhibited greater sensitivity to immunotherapy in the high-risk group (P < 0.001). Drug sensitivity analysis suggested that the predictive model can also be applied to the choice of chemotherapy drugs. RT-qPCR analysis also validated the accuracy of the constructed model based on nine ICD-related lncRNAs. The prognostic model constructed based on the nine ICD-related lncRNAs showed good application value in assessing prognosis and guiding clinical therapy.
Rapid, label-free classification of glioblastoma differentiation status combining confocal Raman spectroscopy and machine learning
Authors: Wurm Lennard M. , Fischer Björn , Neuschmelting Volker , Reinecke David , Fischer Igor , Croner Roland S. , Goldbrunner Roland , Hacker Michael C. , Dybaś Jakub , Kahlert Ulf D.
Published: November 2023

Multifactor classification of tumor stem cells and their differentiated counterparts by label-free diagnostics.
Ti3C2Tx MXene-embedded MnO2-based hydrophilic electrospun carbon nanofibers as a freestanding electrode for supercapacitors
Authors: Wang Zhaorui , Zhang Deyang , Guo Ying , Jiang Hao , Wang Di , Cheng Jinbing , Chu Paul K. , Yan Hailong , Luo Yongsong
Published: November 2023

MnO2 nanoflowers electrodeposited on a self-supported and electroconductive electrode in which 2D Ti3C2Tx nanosheets are encased in carbon nanofibers.
Synthesis of 3-aminoindenes and cis-1-aminoindanes by Zn(OTf)2-catalyzed cyclization of o-alkynylbenzaldehydes with tertiary alkyl primary amines
Authors: Yao Tuanli , Zhu Rui , Liu Tao
Published: November 2023

A one-pot two-step cyclocarboamination of o-alkynylbenzaldehydes with tertiary alkyl primary amines was realized to afford a range of 3-aminoindenes and cis-1-amino-2-arylindanes with excellent chemo- and diastereo-selectivity.
1,2-Fluorosulfenylation of unactivated alkenes with thiols and a fluoride source promoted by bromodimethylsulfonium bromide
Authors: Yang Zihui , Liu Jia , Xie Lan-Gui
Published: November 2023

A practical method that enables the fluorosulfenylation of unactivated alkenes and gaseous ethylene processing directly with thiols and fluoride salts is presented.
The PEC performance of BiVO4 was enhanced by preparing the CoFeBi/BiVO4 photoanode using an ultrafast photoassisted electrodeposition method
Authors: Zhao Xiaojuan , Rui Yifan , Bai Yan , Huang Jingwei , She Houde , Peng Jianhong , Wang Qizhao
Published: November 2023

The BiVO4 photoanode modified with bimetallic CoFeBi exhibits a significant enhancement in photoelectrochemical (PEC) water splitting performance.
Electrochemical behavior of aluminum in triethylamine hydrochloride–aluminum chloride ionic liquid
Authors: Borozdin Alexey V. , Shevelin Peter Yu. , Elterman Vladimir A. , Yolshina Liudmila A.
Published: November 2023

Electrochemical deposition/dissolution of aluminum in a chloroaluminate ionic liquid based on triethylamine hydrochloride is complicated due to the formation of molecular aluminum chloride.
The intrinsically low lattice thermal conductivity of monolayer T-Au6X2 (X = S, Se and Te)
Authors: Ji Yupin , Chen Xihao , Sun Zhehao , Shen Chen , Wang Ning
Published: November 2023

The lattice thermal conductivities of T-Au6S2, T-Au6Se2 and T-Au6Te2 along the x-axis (y-axis) are 0.25 (0.23), 0.30 (0.21) and 0.12 (0.10) W m−1 K−1 at 300 K, respectively. These values are much lower than those of many materials.
The nature of the electronic ground state of M2C (M = Ti, V, Cr, Zr, Nb, Mo, Hf, Ta, and W) MXenes
Authors: García-Romeral Néstor , Morales-García Ángel , Viñes Francesc , de P. R. Moreira Ibério , Illas Francesc
Published: November 2023

A systematic computational study is presented aimed at accurately describing the electronic ground state nature and properties of M2C (M = Ti, V, Cr, Zr, Nb, Mo, Hf, Ta, and W) MXenes.
Highly efficient helium purification through a dual-membrane system: insights from molecular dynamics simulations
Authors: Pakdel Siamak , Erfan-Niya Hamid , Azamat Jafar , Hasanzadeh Amir
Published: November 2023

Initial configuration after 50 ns MD simulation under applied pressure of 2 MPa converted to final configuration. Complete separation of three components (He/N2/CH4) was simultaneously obtained by the dual membrane system.
Correction: The solution structures and relative stability constants of lanthanide–EDTA complexes predicted from computation
Authors: O’Brien Ravi D. , Summers Thomas J. , Kaliakin Danil S. , Cantu David C.
Published: November 2023

Correction for ‘The solution structures and relative stability constants of lanthanide–EDTA complexes predicted from computation’ by Ravi D. O’Brien et al., Phys. Chem. Chem. Phys., 2022, 24, 10263–10271, https://doi.org/10.1039/D2CP01081J.
Enhancing carbon capture efficiency with a large-sized bionic jellyfish-carbonic anhydrase complex
Authors: Zhu Xing , Du Chenxi , Gao Bo , He Bin
Published: November 2023

This study developed a robust bionic jellyfish-carbonic anhydrase complex (Bj-CA) for CO2 efficient capture.
Manipulation of the electrical and memory properties of MoS2 field-effect transistors by highly charged ion irradiation
Authors: Sleziona Stephan , Pelella Aniello , Faella Enver , Kharsah Osamah , Skopinski Lucia , Maas André , Liebsch Yossarian , Schmeink Jennifer , Di Bartolomeo Antonio , Schleberger Marika
Published: November 2023

Field-effect transistors based on molybdenum disulfide (MoS2) exhibit a hysteresis in their transfer characteristics, which can be utilized to realize 2D memory devices. Ion irradiation is used to manipulate the hysteresis.
Machine learning method aided discovery of the fourth-generation EGFR inhibitors
Authors: Zhang Yu , Li Yan
Published: November 2023

Machine learning assists exploration of fourth-generation EGFR inhibitors, feature contributions (SHAP), pharmacophore modeling, and molecular docking.
Polar moiety functionalized, controlled gelation to obtain highly efficient hydrogel nanocomposite: an expansion of green synthetic strategy
Authors: Sandhu Anuradha , Pandey Vivek , Pandey Tejasvi
Published: November 2023

Hydrogels have attracted worldwide attention in the era of sustainable development, and nanocomposite hydrogels have proven their efficient role as smart materials because of their stable behaviour and expanded surface area.
Co–MoCx supported on N-doped CNTs for efficient hydrogen evolution reaction under alkaline medium conditions
Authors: Shen Weilin , Suen Dawson Wai-Shun , Sze Eric Tung-Po , Chen Xiao , Liang Changhai , Tsang Chi-Wing
Published: November 2023

CoMoCx/N-CNTs prepared by a simple pyrolytic method afforded a high ECSA of 477.25 cm−2 and boosted the HER activity by 2-fold.
Overcoming the problem of insolubility to controllably synthesize AuCo alloy as a high performance electrocatalyst for the oxygen reduction reaction
Authors: Ren Zhandong , Xie Zhiqiang , Ming Ruoxi , Zhan Yiping , Xin Yuefei , Han Juanjuan , Zhuang Lin , Liu Yi , Zhu Yuchan
Published: November 2023

Overcoming the insolubility of Au and Co, AuCo alloy was synthesized by magnetron sputtering as a high-performance electrocatalyst for the oxygen reduction reaction.
Design and development of a Sb2WO6/graphene oxide (2D) nanocomposite as novel electrochemical metal-ion sensor and improved photocatalyst for the degradation of tetracycline
Authors: ul haq Zia , Nazir Irfan , Qureashi Aaliya , Ganaie Firdous Ahmad , Bashir Arshid , Fatima Kaniz , Shah Wajaht Amin , Rizvi Masood Ahmad
Published: November 2023

Solvothermal synthesis of hierarchical orthorhombic Sb2WO6 nanostructures on layered GO for heavy metal ion sensing and photocatalysis.
Design, synthesis, molecular docking and molecular dynamic studies of novel benzimidazole–thiazole derivatives as potent and selective COX-2 inhibitors
Authors: Irmak Nurdan Ebru , Saglık Begum Nurpelin , Celik Ismail , Tahsin Sen Hasan , Ozkay Yusuf , Ayhan-Kılcıgil Gülgün
Published: November 2023

New benzimidazole–thiazole compounds were synthesized to selectively inhibit COX-2.
Atropisomers and a copper(ii) complex derived from 1,3-dimethyl-5-(8′-quinolinylazo)-6-aminouracil: structures, magnetism and biological properties
Authors: Nandi Nishithendu Bikash , Das Nishan , Ghanta Susanta , Puzari Krishti Rekha , Dutta Pranab , Kłak Julia , Sieroń Lesław , Maniukiewicz Waldemar , Misra Tarun Kumar
Published: November 2023

Quinolinylazo-6-aminouracil acts as an excellent potential precursor to form bioactive atropisomers of 8-azaxanthine and an axially elongated distorted square pyramidal Cu(ii) complex.
Correction: Nickel carbonate (Ni2(CO3)3) as an electrocatalyst and photo-electrocatalyst for methanol electro-oxidation
Authors: Udachyan Iranna , Bhanushali Jayesh T. , Patra Shanti G. , Zidki Tomer , Mizrahi Amir , Meyerstein Dan
Published: November 2023

Correction for ‘Nickel carbonate (Ni2(CO3)3) as an electrocatalyst and photo-electrocatalyst for methanol electro-oxidation’ by Iranna Udachyan et al., J. Mater. Chem. A, 2023, 11, 17769–17778, https://doi.org/10.1039/D3TA02713A.
An archaeoacoustic study on shape: the case study of the Iffland Theatre’s history (1802–1817)
Authors: Postma Barteld N.J. , Katz Brian F.G.
Published: November 2023

Previous studies have discussed six pre-Sabine quantifiable guidelines employed in room acoustic design: voice directivity, audience rake, “echo theory”, stage acoustics, reverberation, and length, width, and height ratios. Around the turn of the 18th century, these notions led to two shapes that were theoretically regarded optimal for rooms with acoustical demands: ellipse and semi-circle. The first of these shapes to be tested was the ellipse in the design for the Iffland Theatre (1802–1817). As the resulting acoustics were notoriously poor, contemporary architects and acousticians discussed the grounds for the failed acoustics as well as possible corrections. Multiple subsequent halls were also based on lessons learned from this acoustic failure. As part of this archaeoacoustics research, geometric acoustic numerical simulations were employed to estimate the actual and renovated room acoustic conditions. Three configurations of the hall have been reconstructed. Results show that the hall’s shape led to sound focusing and that the rounded proscenium arch likely induced echoes. Proposed solutions of the time to increase the scattering or absorption appear unlikely to have solved the observed acoustic problems.
Quantification of amplitude modulation of wind turbine emissions from acoustic and ground motion recordings
Authors: Blumendeller Esther , Gaßner Laura , Müller Florian J.Y. , Pohl Johannes , Hübner Gundula , Ritter Joachim , Cheng Po Wen
Published: November 2023

Amplitude modulation (AM) is a common phenomenon associated with wind turbine (WT) related noise annoyance. Within the interdisciplinary project Inter-Wind, acoustic, ground motion, and meteorological data are captured to be evaluated with noise reports of residents living near a wind farm in Southern Germany. The recorded data builds a solid data base for the evaluation of AM. The occurrence of AM is detected within acoustic and ground motion data and set in relation to all available data, including WT operational parameters, meteorology, and noise reports. In this study, the origins of detected AM are tones at 57.8 Hz and 133 Hz, related to the generator and drive train, which are amplitude modulated by the blade passing frequency. AM detection was successful both with acoustic as well as ground motion data. A comparison of a method for AM detection developed by the Institute of Acoustics (IOA reference method) with a method specifically developed to detect AM in ground motion data showed that the reference method detected AM three to six times more often than the newly developed method. AM occurred most likely during stable atmospheric conditions, with a positive lapse rate, and was (albeit to a small degree) more likely to be detected when residents reported higher levels of annoyance.
Analysis of TPACK Learning Media Ability of Biology Teachers in Tanjungpinang City Coastal Area
Authors: Nevrita Nevrita , Oprasmani Elfa , Sumarni Een
Published: November 2023

The ability of TPACK in learning media is the ability of teachers to integrate pedagogy, content, and technology into the learning media used. But in fact, there are still biology teachers who are unskilled in using technology in learning media. Some teachers only use PowerPoint as a learning media in the classroom. So therefore, it is necessary to analyze the ability of TPACK learning media of biology teachers in coastal. Thus can be used as information to improve the quality of learning media developed by teachers in each school of Tanjungpinang city coastal area, in order to goals of SDGs in its education of the city. This research aim to describe the profile of the ability of TPACK learning media Biology teacher in Tanjungpinang city coastal area. The data collection technique was carried out using the learning media TPACK Biology and Science questionnaire. The questionnaire was given to 14 Tanjungpinang High School Biology teachers who are in the area coast. Research results show that TPACK Learning Media ability High School Biology Teachers in the Coastal Area of Tanjungpinang City of 76.79% with good criteria.
Exposition Of Green Energy Development Integration In Mantang Village Area Bintan Regency
Authors: Mujahidin Muhamad , Rusfa  , Paramita Bunga
Published: November 2023

Green Energy from the perspective of energy processing and utilization is fundamental in sustainable regional expansion. This research gathered 12 hamlets in the coordinate area of Mantang Island in Bintan Regency as representatives for realizing the Lagrange and Laplace transform method used is determining utilization targets, regulations regarding the selection of types of energy sources and regulations regarding the use of technology in the form of indicators of extensive evolution. based on proportional accumulation of the observation area from 2020 to 2023, this research implements a form of affiliate quality improvement version and performance calculations, and extensively utilizes economic constraints and technology indicator study patterns, to examine Lagrange and Laplace transform patterns and spatial dissemination of green energy development in the testing area. the results show the following. (1) the causes influencing the development of green energy in the research area indicate that the gradation of impact of the three aspects is growing, and the gradation of impact of one of the qualities is shrinking, and the percentage of divergence is gradually decreasing, which shows the concept of infrastructure versus environmental preferences. (2) Large Mantang and Small Mantang in the current conditions and the tendency to use green energy and changes in the islands need to be taken into account. Mantang Besar, Bintan Regency is in a good status, while Mantang Kecil has little green energy exploitation potential and it is hoped that this will be explored. (3) The sample area shows “high-high” or “low-low” agglomeration, the result is special treatment in the form of a subsidy on the selling priceelectricity produced using renewable energy and subsidies for the purchase price of fuel originating from renewable energy, utilization of bioenergy for electricity generation reached 1,717.9 MW
The Outside of Port Limit (OPL) as a new maritime zone to overcome marine pollution due to oil sludge impacting the coast of Bintan, Indonesia to actualise sustainable development
Authors: Thahira Atika , Syofyan Syofirman , Daulay Zainul , Ferdi
Published: November 2023

The Coastal pollution in Bintan, Indonesia, caused by illegal oil sludge discharge from vessels breaches the provisions of the International Convention for the Prevention of Pollution from Ships (MARPOL) regarding the sludge oil discharge 30 ppm from tank cleaning and 15 ppm from machinery spaces, which is has been problem since the 1970s until today, The culprit has not been found until now because the problem of proof scientific verification between the pollutant and the impact of the pollution. Based on research using a research paradigm, qualitative methodology, and empirical legal research, The results of this study indicate the eastern segment 2 of the Singapore Strait, which is a grey area, is a source of oil sludge pollution. Therefore, it is recommended to make a strategy to overcome this pollution with establish and regulate a new maritime zone, namely, outside of port Limit (OPL) in the United Nations Convention on the Law of the Sea (UNCLOS), thus littoral state can establish OPL in their territorial sea to monitor and prevent illegal sludgde oil discharges into the sea and especially the problem of oil sludge pollution in Bintan can be overcome. Therefore, sustainable development goals can be realized.
An Overview of the Indonesian Abalone Industry: Production, Market, Challenges, and Opportunities
Authors: Dwi Eny Djoko Setyono , Hollanda Arief Kusuma
Published: November 2023

The Indonesian abalone industry has been experiencing growth in recent years and holds significant potential for further expansion. This paper provides a comprehensive review of the current state of the abalone industry in Indonesia, including production processes, markets, and trade, as well as the challenges and opportunities faced by the industry. The study found that the growth of the Indonesian abalone industry is driven by both the domestic market and the increasing demand for Indonesian abalone in international markets. Despite these opportunities, the industry faces various challenges, such as illegal fishing practices, intense competition, and fluctuating prices. The Indonesian government has implemented regulations to promote sustainable harvest and trade practices to address these challenges. The industry is focused on producing high-quality abalone to maintain its competitive position in the global market. The Indonesian abalone industry needs to overcome these challenges To sustain its growth in the future, expand its market reach through international trade, and continuously produce high-quality products. This review provides valuable insights into the Indonesian abalone industry and highlights potential future directions for growth. The findings of this study could be useful for industry players, policymakers, and researchers interested in the development of the Indonesian abalone industry.
Synthesis of Mil-100(Fe)@Fe3O4 Composite using Zircon Mining Magnetic Waste as an Adsorbent for Methylene Blue Dye
Authors: Pasaribu Marvin Horale , Karelius Karelius , Ramdhani Eka Putra , Agnestisia Retno , Pereiz Zimon , Toepak Erwin Prasetya
Published: November 2023

The objectives of the present study are to synthesize MIL-100(Fe)@Fe3O4 composite and to clarify its ability as an adsorbent for methylene blue dye. The magnetite (Fe3O4) was synthesized using iron precursor from the zircon mining magnetic waste. The MIL-100(Fe) was composited with magnetite using a room-temperature in situ synthesis method. The MIL-100(Fe)@Fe3O4 composite obtained was then characterized using the Fourier transform infrared spectroscopy and X-ray diffraction. The synthesized MIL-100(Fe) and MIL-100(Fe)@Fe3O4 were then used to adsorb methylene blue dye from aqueous phase. The maximum methylene blue removal from both adsorbents was obtained at pH of 9. The adsorption kinetics showed that the adsorption followed a pseudo second-order kinetics model with the rate constant values for MIL-100(Fe) and MIL-100(Fe)@Fe3O4 were 1.012 x 10-2 and 3.963 x 10-2 g/mg.menit, respectively. The results also showed that the adsorption isotherm of MIL-100(Fe) and MIL-100(Fe)@Fe3O4 follows the Langmuir isotherm for adsorption capacities were 137.70 and 151.47 mg/g, respectively. The results indicate that the iron content in the zircon mining magnetic waste as precursor for synthesis MIL-100(Fe)@Fe3O4 composite can be employed as an excellent adsorbent for removal of methylene blue dye from aqueous phase.