bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Microbial Contamination of Toothbrushes and Their Decontamination Using Various Disinfectants
Authors: Joy Tom , Venugopal Sanjay , Sadanandan Sowmya , Mathew Melvin
Published: June 2022

Background:

Toothbrush often gets contaminated with use and also during storage. Although many toothbrush disinfection methods are mentioned in the past literature. To date there no absolute consensus on the topic.

Aims:

This study aimed to evaluate the microbial contamination of toothbrushes and their decontamination using various disinfectants.

Subjects and Methods:

Anin vitrostudy was carried out on 80 subjects with a gingival index (Loe and Silness, 1963) score of two or three received toothbrush and paste with complete oral hygiene instructions. After 1 month, toothbrushes were collected and checked for microbial contamination by aerobic culture. Toothbrushes were divided into four groups (n = 20) and treated with one of the following agents: Group A – 0.2% chlorhexidine gluconate, Group B – Listerine, Group C – Dettol, and Group D – tap water for 1 h. After an hour, the brushes were further cultured to evaluate the efficacy of each agent. Statistical procedures were performed using Statistical Package for the Social Sciences (SPSS) 16 software. Inferential statistics were performed using Chi-square analysis.P< 0.05 was set as statistically significant.

Results:

All the sampled toothbrushes had significant (P < 0.001) bacterial growth after 1 month of use. Most of the brushes were contaminated with Escherichia coli(17.1%). All the tested disinfectants significantly (P < 0.001) reduced bacterial growth and Dettol showed maximum effectiveness (95.3%).

Conclusions:

Toothbrushes significantly get contaminated after use, which is reduced after disinfecting the brushes. Although not 100% effective, all the disinfectants significantly reduced the bacteria, and Dettol was found to be comparatively better than other agents.
Dentists' Knowledge, Attitudes, and Professional Behavior Regarding Silver Diamine Fluoride
Authors: Mehlawat Jiksha , Marya Charu Mohan , Nagpal Ruchi , Kataria Sakshi , Taneja Pratibha
Published: June 2022

Background:

Dental caries is a major public health problem and is handled through either treatment or prevention. Unlike other fluoride-based caries preventive agents, silver diamine fluoride (SDF) can simultaneously prevent and arrest coronal and root dentine caries.

Aim:

The aim of this study is to assess dentists' educational experiences, knowledge, attitudes, and professional behavior regarding SDF use for caries prevention.

Methodology:

For the cross-sectional survey, a prevalidated questionnaire comprising of 33 questions was being prepared through the Google survey tool of Gmail and was sent to 200 dentists in North India region through Whatsapp groups of different communities or specialties. Data analysis was done using IBM SPSS version 16.

Results:

The response rate of 63.5% was received from 200 dentists, among which 28.8% were general practitioners and 35.2% were both academic and clinical practitioners. Only 5.6% respondents came up having been very well educated about SDF during Bachelors in Dental Surgery and Master of Dental Surgery in the classroom setting and 3.2% in the clinical setting. There were 14.4% participants who reported that they knew very well about what SDF is used for in dentistry, and 9.6% knew how SDF is used for treatment of tooth hypersensitivity, 24.8% knew how SDF is used to treat dental caries. The attitudes of the dentists toward SDF were positive. SDF use was considered a good treatment alternative for restorations in children with behavioral problems (17.6%), for patients who were medically fragile (12%) or had severe dental anxiety (19%) and strongly agreed to it.

Conclusion:

Results suggested that the majority of respondents were lacking in knowledge regarding usage of SDF in dentistry.
Ocular sporotrichosis from a tertiary referral center in Malaysia and review of literature in Southeast Asia
Authors: Ahmad-Fauzi Shazana , Abd-Manan Noranida , Yusof Nor-Sharina , Ibrahim Mohtar , Mohamad Shahidatul-Adha , Muhammed Julieana
Published: June 2022

Ocular sporotrichosis is rare in Malaysia and Southeast Asia and is increasingly reported in endemic areas of Brazil and Peru. We describe six cases of ocular sporotrichosis involving the bulbar conjunctiva and lid with a literature review on ocular sporotrichosis in Southeast Asia. In these series, four patients presented with similar findings of granulomatous lesion at the palpebral conjunctiva within 1–3 weeks. There was one case mistakenly diagnosed as conjunctival concretion due to its multiple yellowish nodules on the palpebral conjunctiva and another case as chalazion due to swelling of the lower lid. All patients showed immunocompetence. Four patients had an immediate contact with sick cats, one patient had a history of skin scratched by a healthy cat, and another patient had a history of gardening without direct contact with cat. Culture from conjunctival biopsy obtained from five patients and from ruptured lower lid nodules of one patient yielded Sporothrix schenckii. The patients were successfully treated with oral itraconazole 200 mg twice daily. Two patients developed symblepharon after completing treatment, while four patients showed good results without any sequelae.
Performance Optimization of Solar PV System Utilized for Cooling System
Authors: Mohammed Omar Hazem , Al-Salmany Ziyad Tariq
Published: June 2022

This work investigates the performance and energy effectiveness of a solar photovoltaic (PV) system used to provide a cooling system for a building in Iraq. To achieve the goal, simulations and optimization are utilized to find the economic feasibility of the building in Iraq. In addition, a comparative study is conducted to compare the economic feasibility of PV cooling based on two options. The first option depends on the conventional electrical grid to offer cooling for the Iraqi building. The second option relies on a solar PV system to provide the electrical power for cooling the same building. The major numerical analysis results revealed that using a PV system can save roughly 45% electrical power compared to the option when the electrical power is drawn from the conventional grid. For this reason, it is predicted that the PV system can save a higher level of greenhouse gas (GHG) emissions compared to the first option. The results of this research revealed that the cooling load of the building in Samawah, Iraq equalled 600 kW. The PV system required to operate the cooling of the Samawah building during summer equals 18 kW peak. Using a solar PV system would be more economically feasible than the electrical power drawn from the electrical grid. Utilizing PV cooling is considered beneficial for the environmentas it can save GHG emissions that cause significant air quality problems and global warming.
Postbuckling behaviour of isotropic thin rectangular plates with one free edge
Authors: Adah E.I. , Onwuka D.O. , Ibearugbulem O.M. , Ubi S.E. , Nwigwe E.E.
Published: June 2022

This work aims to evaluate the individual stiffness of six plates’ boundary conditions with one free edge to obtain the specific mathematical models for predicting the postbuckling loads of the six plates’ boundary conditions under consideration. The shape profiles of each of the six plates were differentiated and substituted into the individual stiffness integrals to obtain the numerical values of the individual stiffness. The individual stiffness values were then substituted into the total bending and membrane stiffness expressions and evaluated. The resulting total and membrane stiffness expressions were thereafter substituted into the general postbuckling equation and evaluated to obtain specific mathematical models for the six plate types to predict the postbuckling loads of each plate. The newly formulated mathematical models were validated by carrying out numerical predictions of the postbuckling loads of each plate. The critical load obtained was compared with those in the literature and was found adequate. Additionally, the results showed a gradual increase in the strength of plate beyond the initial yield point which is in line with the behavior of plates. Based on these observations it was concluded that the newly formulated mathematical models for predicting the postbuckling strength of thin isotropic rectangular plates considered here were adequate and that the models will provide an easy means of analyzing thin plates for postbuckling loads.
Development and validation of a colorimetric method for determination of tadalafil using ion-pair complexation with bromophenol blue
Authors: Ajima Ukpe , Idowu Olaitan James , Poyi Olanike Catherine , Onah Johnson Ogoda
Published: June 2022

Tadalafil belongs to the class of phosphodiesterase (PDE5) inhibitors used for the management of erectile dysfunction and other conditions. The study reports a colorimetric method for the determination of tadalafil. The method is based on the reaction of the drug with bromophenol blue in acetate buffer (pH 2.8) to form a yellow coloured complex showing maximum absorbance at 415 nm. A linear calibration curve was obtained between 2 and 22 μg/mL of tadalafil with correlation coefficient (r2) of 0.972 and molar absorptivity of 15,267 Lmol-1cm-1. The method similarly demonstrated good precision with intra-day precision ranging from 3.68-5.89 %RSD and inter-day precision of 0.66 – 4.45 % RSD. The developed method was successfully applied to the analysis of tadalafil in tablet formulation and could serve as a useful tool in the quality assessment of this medication.
Identification of Bioactive Compounds in Sclerotia Extracts from Pleurotus tuber-regium (Fr.) Sing. using Gas Chromatograph– Mass Spectrometer (GC-MS)
Authors: Odiase-Omoighe J.O. , Agoreyo B.O.
Published: June 2022

King tuber mushroom (Pleurotus tuber-regium) is a tropical mushroom commonly seen in Australia, Africa and Asia. Trado-medical practitioners use the sclerotia for the treatment of various health disorders. This research aimed at identifying the biologically active compounds present in the sclerotia of this mushroom. In this study, the fungus was first extracted with methanol and re-extracted with ethyl acetate (EA) and dichloromethane (DCM) separately to obtain EA and DCM extracts. Gas chromatography–mass spectrometric (GC-MS) technique was used for the identification of compounds present in EA and DCM extracts. Results revealed the presence of a total of at least twenty-six (26) compounds with 14 and 12 from EA and DCM extracts respectively. The bioactives include n-Hexadecanoic acid, Oleic acid, 10-Octadecenal, Palmitoleic acid, 9, 17-octadecadienal-(z), 11-octadecenoic and methyl ester-(z). In EA extract, n-Hexadecanoic acid had highest concentration (37.67%) followed by 20.65% of 9,12 Octadecadienoic acid and the least was 9,17 Octadecadienal with 0.539%. In DCM extract, 11-Octadecenoic acid methyl ester was most abundant (18.344%) followed by Pentadecanoic acid 14 methyl-methyl ester (14.105%) and the least (4.058%) was 9,12-Octadecadienoic acid. These compounds possess various reported medicinal properties (such as the treatment of high blood pressure, diabetes, asthma, fever and cancer) that could be harnessed for health benefits. Other identified compounds with unknown functions are Trans-2-Dodecen-1-ol trifluoroacetate, cis-11-Hexadecenal, Methyl-18-methylnonadecanoate and Methyl-18-methyl-tetracosanoate. This identification is useful for the establishment of the medicinal properties of the mushroom and isolation of the bioactive compounds, which production can further be enhanced by cost-effective biotechnology techniques.
Thermal Stability of Bio-Polymers and their Blends
Authors: Eiroboyi Itohan , Ikiensikimama S. S.
Published: June 2022

Studies from research have shown that one of the major problems associated with the use of polymers during polymer flooding is polymer degradation. Polymers lose their viscosity as well as their efficiency in the presence of high temperatures. Hence, the need for polymers that are environmentally friendly and can withstand high reservoir temperatures. Therefore, this study was necessary to address this challenge. Three commercial bio-polymers currently being used in the oil and gas industry were used in this study, they are Xanthan gum, Guar gum, and the Imported Locust bean gum (LBG). Also used in this study were, Gum Arabic and Nigerian Locust bean gum (LBG). The thermal stabilities of these polymers were investigated at different temperatures to determine their thermal resistances at high temperatures. Polymer blending was applied to study the impact of blending on the thermal stabilities of the different polymer blends formulated. Rheological analysis was carried out before and after subjecting the polymers and polymer blends using temperatures from 50oC to 150oC. The results showed that Guar gum, Imported LBG, and Nigerian LBG displayed improved resistances from 75oC to 90oC compared to Xanthan gum, which was thermally stable up to 70oC. Furthermore, the blends showed higher stable temperatures compared to that of polymers alone and also compared to the thermal stability of Xanthan gum. This study showed that the blends would perform better at high-temperature reservoir conditions.
Effect of chloroprocaine combined with morphine on analgesia, adverse reactions and dynamic changes in inflammation in patients receiving TURP
Authors: Zhu Lin , Lin Peili , Lv Xulei , Zhao Jingyu , Li Mengmeng
Published: June 2022

Purpose: To investigate the influence of chloroprocaine combined with morphine on the analgesic effects, adverse reactions and inflammation factors in patients receiving transurethral resection of the prostate (TURP).Methods: A total of 80 patients with benign prostatic hyperplasia (BPH) in the Fourth Medical Center of Chinese PLA General Hospital, Beijing 100048, China, were divided into morphine group and combination-therapy group (morphine combined with chloroprocaine). Pain index, changes in inflammatory factors and incidence of adverse reactions in the two groups of patients were assessed.Results: The morphine group and combination-therapy group showed basic profile prior to the treatments. Visual Analogue Scale (VAS) scores before operation and 6 h after operation in the morphine group were similar to those in the combination-therapy group, but the scores at 12, 24 and 48 h after operation in the combination-therapy group were significantly lower than those in the morphine group. Similarly, the combination-therapy group showed lower levels of substance P (SP) and bradykinin (BK) at 12, 24 and 48 h after operation than the morphine group (p < 0.05). Both groups exhibited similar levels of serum inflammatory factors before the operation, but the levels decreased in the combination-therapy group when compared with those in the morphine group after operation (p < 0.05). The combination-therapy group also showed a lower incidence of adverse reactions than the morphine group.Conclusion: Chloroprocaine combined with morphine effectively ameliorates postoperative pain, lowers secretion of tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10), and decreases the incidence of postoperative adverse reactions, thus affording a high level of safety after operation.
Título en español.
Authors: Cook Melville T.
Published: June 2022

Resumen en español.
EVALUATION OF PHENOLIC COMPOUNDS IN WHITE WINES TREATED WITH ENZYMES
Authors: Scutarasu Elena Cristina , Cotea Valeriu , Luchian Camelia Elena , Trinca Lucia Carmen , Scutarasu Andrei
Published: June 2022

Wine's quality is influenced both by the grape characteristics and winemaking protocols. Awareness of the significant role of enzymes preparations in beverages technologies contributes to the optimization of the manufacturing process, for improving the chemical composition of the resulting wine and its organoleptic properties. This paper focuses on monitoring the impact of different commercial enzymes (pectinases and β-glycosides) on the main phenolic compounds content of Sauvignon blanc wines. For this experiment, ten phenolic compounds were quantified using a liquid-chromatography (LC) system coupled with ion trap mass spectrometer. The results indicated a significant influence of enzymes on wine’s phenolic fraction. Experimental samples presented high content in protocatechuic acid (9.99 - 13.75 μg/mL) and caftaric acid (2.69 - 9.80 μg/mL). The use of pectinases lead to an increase of phenolic compound’s concentration compared to the control.
Uji Kualitas Fisik dan Nilai pH Silase Pakan Komplit Berbahan Dasar Jerami Jagung (Zea Mays) dengan Penambahan Azolla (Azolla pinnata) sebagai PakanTernak Ruminansia
Authors: Sandi Ricky , Kadir Muhammad Jurhadi , Rasbawati Rasbawati
Published: June 2022

Penelitian ini bertujuan untuk mengetahui kualitas fisik dan nilai pH silase pakan komplit berbahan dasar jerami jagung (Zea mays) dengan penambahan Azolla (Azolla pinnata) sebagai pakan ternak ruminansia. Menggunakan metode rancangan acak lengkap (RAL) dengan empat perlakuan dan tiga ulangan. S1 (jerami jagung 50% + azolla 30% + pakan tambahan 20%), S2 (jerami jagung 50% + azolla 25% + pakan tambahan 25%), S3 (jerami jagung 50% + azolla 20% + pakan tambahan 30%) dan S4 (jerami jagung 50% + azolla 15% + pakan tambahan 35%). Hasil Sidik ragam menunjukkan bahwa silase pakan komplit berbahan dasar jerami jagung dengan penambahan azolla sebagai pakan ternak ruminansia tidak berpengaruh nyata (P>0.05) terhadap warna, jamur, aroma dan tekstur (kualitas fisik) dan pH. Disimpulkan bahwa penambahan azolla (Azolla pinnata) pada level yang berbeda terhadap silase pakan komplit berbahan berbahan dasar jerami jagung (Zea mays) tidak berpengaruh terhadap pH dan kualitas fisik silase. Hasil terbaik diperoleh pada perlakuan S1 dengan penambahan azolla sebanyak 25%.
This study aims to determine the physical quality and pH value of complete feed silage made from corn straw (Zea mays) with the addition of azolla (Azolla pinnata) as ruminant feed. Using a completely randomized design (CRD) method with four treatments and three replications. S1 (corn straw 50% + azolla 30% + additional feed 20%), S2 (corn straw 50% + azolla 25% + supplementary feed 25%), S3 (corn straw 50% + azolla 20% + supplementary feed 30%), and S4 (Corn Straw 50% + Azolla 15% + Additional Feed 35%). The results of the variance test showed that complete feed silage made from corn straw with the addition of azolla as ruminant feed had no significant effect (P>0.05) on color, mold, scent and texture (physical quality) and pH. It was concluded that the addition of azolla (Azolla pinnata) at different levels to complete feed silage made from corn straw (Zea mays) did not affect the pH and physical quality of silage. The best treatment in S1 with the addition of azolla as much as 25%
GREEN MANURE AS A SOIL FERTILITY AND ENVIRONMENTAL OPTION IN SEMIARID AGROSYSTEMS: MINERALIZATION RATE AND N CONTENT
Authors: Hernández-Herrerías León Bartolomé , De León-González Fernando , Rodríguez-Sánchez Luis Manuel , Barrales-Brito Edgar , Hidalgo Moreno Claudia , Fuentes-Ponce Mariela Hada
Published: June 2022

Green manures are an adequate alternative for improving the availability of nitrogen and phosphorus for crop nutrition, within a global context of decreasing soil fertility and the urgent need to care for the environment. Mixteca region, covers a wide area of central Mexico, characterized by a semi-arid climate, eroded calcareous soil, and rural poverty. With the aim of proposing technologies for improving soil quality and increasing the availability of nitrogen and phosphorus, an experiment was conducted using green manures: Canavalia ensiformis, Dolichos lablab, Leucaena leucocephala and Avena strigosa and Phaseolus vulgaris, that would ensure a balance between N and P release and the requirements of maize cultivation. The rate of enriched soil mineralization with green manures was determined through incubation, controlled for 15 days with CO2 emissions using an OxiTop OC110® kit as an indicator of decomposition. CO2 emissions were greatest in the soil established with Leucaena leucocephala and least in the soil with no fertilizer, with emissions descending in the following order: Leucaena leucocephala > Canavalia ensiformis > Avena strigosa +Phaseolus vulgaris > Dolichos lablab > soil without green manure. It is assumed that a greater flow of CO2 is accompanied by greater mineralization and release of nutrients. The Ntotal in the soil treated with green manures was similar and greater than that of the soil without fertilizer. Soil treated with Avena strigosa+Phaseolus vulgaris contained the highest values of Nmineral (N-ammonium + N-nitrate). POlsen content in soils with green manures was double that of the soil without fertilizer. Incubation provided the opportunity of identifying those green manures with higher agronomic potential in the area under study. The biomass comprising Leucaena leucocephala leaves and tender stems constitute an alternative for improving soil by providing OM. However, when considering the availability of N and P, the Avena strigosa+Phaseolus vulgaris combination is a superior alternative for meeting the needs of maize cultivation.
INTERVENTION AND FORECAST MODELS FOR THE PRICE PAID TO PRODUCER OF BEE (Apis mellifera L.) HONEY IN MEXICO
Authors: Luis-Rojas Samuel , García-Sánchez Roberto Carlos , García-Mata Roberto , Arana-Coronado Oscar Antonio , Ramírez-Valverde Benito
Published: June 2022

Bee (Apis mellifera L) honey is one of the oldest foods that humans have used. Since ancient times, it has been used as a healthy product due to its sweetening and healing properties. In 2020, Mexico produced 54 121 tons (Mg), which ranked the country as the tenth largest producer in the world. The hypothesis was that current honey prices can be explained by previous prices and that they influence the increase in the population of hives and the production of honey in Mexico. To test this hypothesis, the objective of this research was to develop a forecast model for the annual average prices of honey in Mexico (AAPH). The data comprised the 1966 to 2019 prices and the Box-Jenkins methodology of Autoregressive Integrated Moving Average (ARIMA), with and without intervention, was used. The parameters of the models were estimated with the maximum likelihood method of the SAS® software, while the structural change was calculated with the corresponding library (strucchange) of the R software. A model based on the AAPH series was adapted for the 1966−2019 period and validated with data from 2018 and 2019. The series presents five periods of trend structural changes of AAPH: 1966−1985; 1986−1995; 1996−2003; 2004−2008; and 2009−2019. The best estimated model without intervention was ARIMA (1, 1, 1) and the best model with intervention was ARIMA (1, 1, 0), which indicates that the prices of previous years can explain the AAPH. The predictions had a mean absolute percentage error (MAPE) of 8.16 % for the model without intervention and 4.02 % for the model with intervention. Both estimated models suggested that the AAPH have an upward trend in the medium term. The ARIMA model with intervention provided a more accurate estimation of the AAPH and information to plan and make decisions for the next five years.
DESARROLLO DE COMPETENCIAS PARA LA CULMINACIÓN DE PROYECTO DE TESIS EN EL DEPARTAMENTO DE INGLÉS
Authors: Dabaje Fátima Omar , González Liz Aneth
Published: June 2022

El proyecto tiene como propósito el aprendizaje del idioma inglés mediante el uso de nuevas herramientas tecnológicas y la formulación de proyectos de graduación, desde la asignatura de Metodología de la Investigación en la carrera licenciatura en Humanidades con especialización en inglés, de la Universidad de Panamá. Dentro del grupo de necesidades detectadas en esta carrera se pueden mencionar: estudiantes que solo optan por cursar estudios hasta el nivel técnico, biblioteca con literatura muy antigua sobre temas del idioma inglés, bajo nivel con relación a la asignatura Metodología de la Investigación, para la realización del Trabajo de Graduación. Para ello, el Departamento de Inglés ha centrado su atención en fomentar y actualizar la utilización de recursos tecnológicos en el proceso de enseñanza –aprendizaje, incrementar el número de horas clases en la asignatura Metodología de la Investigación que solamente se ve en el quinto semestre de la carrera; de esta manera, se estaría dentro de las exigencias en la educación del siglo XXI. La investigación es participativa y de campo porque los estudiantes aplican sus conocimientos en un contexto real y de enfoque determinado. El diseño de investigación es transeccional, es decir, se realizará en un solo momento. La muestra utilizada en el estudio estuvo conformada por 50 estudiantes de la Universidad de Panamá que estén o hayan cursado la materia Metodología de la Investigación, la cual forma parte del plan de estudio de la Licenciatura en Humanidades con especialización en el idioma inglés. La técnica utiliza fue la encuesta. Para su aplicación, se diseñó un instrumento con ocho (8) preguntas de respuestas cortas. En el análisis preliminar del estudio los estudiantes manifiestan la necesidad de utilizar aplicaciones tecnológicas, mejorar las metodologías, reconocen el desarrollo de habilidades en el diseño del trabajo de graduación, también el desarrollo de habilidades actitudinales.
PRESCRIPCIÓN POTENCIALMENTE INAPROPIADA EN ADULTOS MAYORES UTILIZANDO LOS CRITERIOS STOPP-START EN LA POLICLÍNICA DE SAN FRANCISCO. PERIODO ENERO 2021-JUNIO 2021
Authors: Saenz Valencia Larissa Yadira
Published: June 2022

Los problemas relacionados con los medicamentos pueden ser ocasionados por la prescripción potencialmente inapropiada de medicamentos (PPIM). Una herramienta recomendada para su identificación es el criterio STOPP (Older Persons’ potentially inappropriate Prescriptions) - START (Screening Tool to Alert doctors to Right Treatment). El objetivo del estudio es determinar PPIM en adultos mayores que reciben atención farmacéutica en la Policlínica de San Francisco. Materiales y métodos: Estudio farmacoepidemiológico observacional descriptivo prospectivo, que evalúa la calidad del uso de los medicamentos. Lugar de trabajo: Policlínica de San Francisco. Población en estudio: adultos mayores de 60 años, que recibieron seguimiento farmacoterapéutico durante el período de enero 2021 a junio 2021. Las PPIM se identificaron utilizando los criterios STOPP-START, versión 2014; se seleccionaron los más adecuados para evaluar la farmacoterapia de pacientes ambulatorios. Resultados: Cincuenta pacientes mayores de 60 años recibieron seguimiento farmacoterapéutico en la Policlínica de San Francisco; 47 (94,0%) pacientes con al menos una PPIM correspondiente a un criterio STOPP. Mediante 17 de los 41 criterios STOPP seleccionados se identificaron 145 PPIM. Mediante 7 de los 11 criterios START seleccionados se identificaron 50 PPIM. Medicamentos con mayor cantidad de PPIM: benzodiacepinas e inhibidores de la bomba de protones. Conclusiones: Se identificó una elevada prevalencia de PPIM. Los datos obtenidos permiten valorar la utilidad de estos criterios en la detección de PPIM. Los criterios STOPP-START se incluyeron como respaldo en la toma de decisiones durante el seguimiento farmacoterapéutico, para generar intervenciones farmacéuticas que optimicen la farmacoterapia. Estas actividades contribuyen a la seguridad del paciente, una dimensión de la calidad en salud.
DISEÑO DE UN SISTEMA TECNOLÓGICO EN LA TIENDA
Authors: Gómez Anayansi
Published: June 2022

El propósito de este proyecto, elaborado en la empresa MELO S.A., específicamente la que está ubicada en el corregimiento Juan Díaz de la Ciudad de Panamá, es dar a conocer o informar tanto el personal y colaboradores que trabajan en esa tienda, como a la clientela del sector, la importancia de utilizar como una ventaja estratégica, la tecnología y su operatividad en cada puesto de trabajo. Así como la necesidad para agilizar las funciones habituales que se llevan de manera cotidiana dentro de la tienda. Es por ello por lo que la innovación y el cambio tecnológico se consideran factores claves para el crecimiento económico de la empresa, que permitan la ejecución o el desarrollo de las operaciones más eficientes y eficaces; lo cual optimiza, se reducen o se eliminan acciones que en el pasado imposibilitaba una cierta flexibilidad en los procesos. En este sentido el Banco Interamericano de Desarrollo (BID) apoya la creación de empresas de base científico-tecnológica para potenciar la productividad de la economía y enfrentar los desafíos socio ambientales en Latinoamérica, y acortar las “brechas enormes” con el mundo desarrollado. Como preámbulo al estudio ya se realizó un sistema de software donde se obtiene un avance tecnológico de cobro computarizado y con factura fiscal, esto conlleva rapidez en los procesos de cobro, menos fila, clientes satisfechos, menor tiempo realizando sus compras y ejecutando el pago, además de conocer el inventario de los productos en venta, al cierre de la empresa.
Combating psychological distress with psychedelics in cancer patients
Authors: Fatima Syeda Zainab , Zaheer Saba
Published: June 2022

Cancer is the leading cause of death worldwide and being diagnosed with cancer can be the source of severe pain and emotional distress to patients. It is not uncommon to find symptoms of depression, anxiety, hopelessness, loss of will to live, and meaning of life. Mitchell et al, found that the symptoms of depression and anxiety are present among 30-40% of hospitalized cancer patients, and 70-90% of cancer patients experience significant pain 1. These symptoms are found to have further debilitating effects on patients which include, non-compliance to medications, decreased quality of life and social functioning, suicidal thoughts, and poor progression and outcomes of the disease.
---Continue
Integral assessment of drinking water from underground sources of the Salgir river basin
Authors: Ivanyutin Nikolay M. , Podovalova Svetlana V. , Dzhaparova Ayshe M.
Published: June 2022

Introduction. Most of the steppe zone of Crimea has a shortage of surface water resources. Therefore, groundwater is used for drinking water supply. Over the past few decades, the growth of anthropogenic activities has led to its widespread pollution. The daily use of water that doesn’t meet the standards can have a negative impact on the health of local residents. The problem of satisfying the population with water that is harmless in its chemical composition makes it necessary to conduct studies to assess its quality and determine the risk to public health according to the regulatory documents in force to develop measures to bring their quality composition to the normative level. The purpose of the study is to assess the risk to the health of the population from pollutants of underground water sources contained in drinking water located in the Salgir river basin. Materials and methods. This work presents the results of the study of the groundwater quality. The samples were extracted in the Salgir river basin. The study was based on the testing of health risk calculations set forth in P 2.1.10.1920-04 and MR 2.1.4.0032-11. The initial data were information on the results of chemical analyses of groundwater for 2018 and 2019. Results. As a result of the calculation of olfactory-reflex and non-carcinogenic risks of 178 drinking water sources, as well as calculation of an integral indicator characterizing the dangerous impact of water on health, the most significant role in the formation of organoleptic effects was revealed to be provided by the smell of water and its stiffness, and non-carcinogenic - by nitrates and in one case by boron. Limitations. Firstly, a carcinogenic risk assessment was not carried out due to the lack of data on toxic components (arsenic, cadmium, lead and others) in water. Secondly, not all settlements located in the Salgir river basin are included in the study, because of the lack of data on the quality of groundwater for these villages. Conclusion. The calculated values of integral indicators, combining these risks, made it possible to assess the quality of water in each water intake and the most significant harmful effects of damage to the organs and systems of the human body. The method used to assess the safety of drinking water makes it possible to develop measures to increase the efficiency of its post-treatment before supplying it to the consumer.
The possibility of using different types of polymeric and polymer-containing reusable containers (literature review)
Authors: Alekseeva Anna V. , Evseeva Irina S. , Ushakova Olga V. , Tregubova Lyudmila Ju.
Published: June 2022

The article contains a review of the literature devoted to research the possibility of using polymeric materials as returnable containers for the supply of water to consumers. When conducting a literature search, the following databases were used: Pubmed, Scopus, Web of Science, MedLine, Global Health, RSCI. The purpose of the work was to collect information on the sources of contamination of drinking water packed in polymer containers based on the literature data and evaluate the possibilities of its safe reuse. Conducted information and analytical studies have shown that the repeated use of polymer containers (in particular, PET containers) may be unreliable, both in terms of chemical and microbiological safety. The paper identifies the main chemical components migrating from polymer containers, which have the greatest impact on the quality of drinking water. The influence of storage temperature, the duration of contact of plastic with water, abrasion of the material, the influence of photochemical aging of bottles and the impact of disinfectants are also considered. The conducted studies have shown that at the moment there are no regulatory and methodological documents regulating the possibility and conditions for the reuse of plastic containers (19-liter bottles), the number of cycles of its reuse, the indicators by which the assessment is made, and the criteria by which the already used container cannot be used further. The possibility of multiple reuse of polymer containers for water storage currently needs to be regulated. There is little literature data on the wear resistance of various types of plastic and the maximum number of cycles of detergents and disinfectants that it can withstand without destroying its structure. Taking into account the data on the destructive changes in polymers under the influence of external factors (temperature, sunlight, etc.), and in the process of treating it with detergents, it is necessary to propose and scientifically substantiate documents regulating the use of returnable packaging, taking into account the materials of modern research. It is also necessary to search for safe, simple and effective methods and means of disinfection of polymer containers.
Relevant issues of determining total organic carbon in water
Authors: Nekrasova Larisa P.
Published: June 2022

Introduction. Total organic carbon (TOC) is a generalized indicator characterizing the pollution of water bodies with organic substances. In accordance with SanPiN 2.1.3864-21 for drinking water, the standard value of TOC content is set equal to 5 mg/dm3. Currently, total carbon analyzers are widely used to determine TOC. Despite its undoubted advantages, the determination of TOC on analyzers has many bottlenecks. Purpose of the study. Analysis of the TOC values of water samples of various origins, obtained using different methods and measurement conditions. Materials and methods. Determination of TOC was carried out with a total carbon analyzer TOC-VCHP (Shimadzu) in accordance with the operation manual of the difference measurement method (TOC) and non-blown organic carbon (NPOC). The objects of study were the water of natural sources, the centralized water supply system of various districts of Moscow, standard solutions of organic compounds. Results. It has been established that during the operation of the analyzer in the analysis of natural and drinking water, incomplete disclosure of humic and fulvic compounds is observed, which cannot be established by standard tests provided for carbon analyzers. The lack of standardized procedures for degassing sparkling water can lead to TOC errors of thousands of percent. Limitation. The limit of determined TOC values was 0.5 mg/dm3. Conclusion. To control the correctness of the determination of TOC in drinking, natural and waste waters, standard samples of humic compounds are required that are characteristic of a particular area with a certified TOC value. It is required to develop and implement a standard procedure for degassing gaseous samples when determining TOC, since the lack of control of this stage of analysis can lead to unacceptable errors in the determination.
Menstrual Leave Policy; Between Gender Sensitivity and Discrimination Against Female Workers
Authors: Widyani I Dewa Ayu
Published: June 2022

The right to get a job and a decent job is a human right, that is why the concept of labor protection emerged. Job protection is specifically given to female workers. One of the special policies that protect female workers is the menstrual leave policy. The menstrual leave policy is a policy that should be appreciated; however, it turns out that this policy actually triggers discrimination against female workers. This research will discuss the basic considerations of special protection for female workers, normative provisions regarding menstrual leave for female workers and discriminatory practices in menstrual leave policies. The menstrual leave policy is the protection of workers and human rights. This policy is contained in Article 81 of the Law of the Republic of Indonesia Number 13 of 2003 concerning Manpower. In practice, female workers do not take menstrual leave because they have the potential to experience discrimination in the form of verbal violence and economic violence.
Boost Zakat Fundraising Through E-Customer Relationship Management in Digital Era
Authors: Doddy Muhammad , Ali Juhary , Hindardjo Anton , Sani Asrul
Published: June 2022

At present, zakat payments allow payment via online. Therefore, the relationship between the Amil Zakat Institution and the muzakki must be strengthened, primarily through online zakat payments. E-CRM or what is known as e-Customer Relationship Management is used to facilitate the implementation of CRM in the world of digital payments. E-CRM allows the Amil Zakat Institution to provide appropriate services to satisfy muzakki and increase muzakki loyalty in paying zakat through online applications. Also, the E-CRM feature is essential for management. Zakat Payer Relations Online, without the e-CRM feature, CRM in the world of online zakat payments cannot be realized. Some literature there is no theoretical model for E-CRM implementation on online zakat payments. Besides, there are shortcomings in previous studies that focused on identifying the importance and categorization of e-CRM features in the various stages of the transaction cycle. So, this study seeks to fill the information gap based on empirical data obtained from the survey. The purpose of this study is to examine the relationship between E-CRM features in online zakat payments and online zakat payer loyalty at various stages of the pre-payment, when-payment, and post-payment transaction cycle. The results of this study indicate that the use of E-CRM in online zakat payment applications can affect the satisfaction and loyalty of online zakat payers. Research contributes to the role of the E-CRM feature in increasing the loyalty of zakat payers online at various stages of the payment cycle. What's more, this study highlights the critical elements of the E-CRM program, where online zakat payment applications must invest to increase the loyalty of zakat payers.
Pengaruh Media Sosial dan Kepercayaan Terhadap Keputusan Pembelian Produk Pada Yuikaa Shop Bima
Authors: Humairah Jihan Fahirah , Haryanti Intisari
Published: June 2022

This study aims to determine the direct effect of social media and trust on product purchasing decisions at Yuikaa Shop Bima. This research method using quantitative methods. The sample used in this study was purposive sampling, the total of 100 respondents who had bought Yuikaa Shop Bima products. The analysis technique used is multiple linear analysis to determine how much influence the independent variables have on the dependent variable collectively and to find out how much influence the independent variables have on the dependent variable individually. Based on the results of this study, it shows that social media and trust have a significant effect on purchasing decisions at Yuikaa Shop Bima either partially or simultaneously.
Pengaruh Capital Adequacy Ratio Dan Non Performing Financing Terhadap Return Bagi Hasil Deposito Mudharabah Bank Umum Syariah
Authors: Syera Inda Arfa , Affiah Hajar
Published: June 2022

Tujuan khusus penelitian ini yaitu untuk mengetahui pengaruh Capital Adequacy Ratio, dan Non Performing  Financing terhadap return bagi hasil deposito Bank Umum Syariah. Pendekatan yang dilakukan dalam penelitian ini adalah pendekatan kuantitatif. Data yang digunakan berupa data sekunder yang berbentuk time series yang berasal dari website Otoritas Jasa Keuangan (OJK). Populasinya adalah data bulanan  dari bulan Januari 2016 sampai periode Desember 2019 sedangkan sampelnya adalah data tahunan dari tahun 2016 sampai tahun 2019. Analisis penelitian yang dilakukan yaitu regresi linier berganda, uji asumsi klasik (uji normalitas, uji multikolinearitas heteroskedastisitas dan uji autokorelasi), dan uji statistik (koefisien determinasi (R2), uji F statistik, dan uji t statistik). Hasil penelitian ini adalah maka variabel capital adequacy ratio dan non performing financing berpengaruh signifikan secara bersama-sama (simultan) terhadap variabel return bagi hasil deposito mudharabah Bank Umum Syariah.
Optimalisasi Akuntabilitas Pada Perangkat Daerah Kabupaten Simalungun
Authors: Tamba Dang Panagaman , Astuti Widya , Sari Maya
Published: June 2022

Penelitian ini bertujuan untuk menguji dan menganalisis apakah kejelasan sasaran anggaran dan sistem pengendalian intern berpengaruh terhadap akuntabilitas kinerja organisasi perangkat daerah kabupaten Simalungun dengan komitmen organisasi sebagai variabel pemoderasi. Jenis penelitian ini menggunakan pendekatan asosiatif. Populasi dalam penelitian ini adalah pegawai-pegawai pada Organisasi Perangkat Daerah Kabupaten Simalungun. Responden yang digunakan adalah Kepala Dinas, Sekretaris, dan Bendahara Pengeluaran dengan jumlah 90 orang. Hasil penelitian menunjukkan bahwa; (1) ada pengaruh kejelasan sasaran anggaran terhadap akuntabilitas kinerja OPD; (2) ada pengaruh sistem pengendalian intern terhadap akuntabilitas kinerja OPD; (3) komitmen organisasi dapat memoderasi pengaruh kejelasan sasaran anggaran terhadap akuntabilitas kinerja; (4) komitmen organisasi dapat memoderasi pengaruh sistem pengendalian intern terhadap akuntabilitas kinerja.
Optimalisasi Return Deposito Mudharabah Di Bank Umum Syariah
Authors: Anggeraini Faulia , Syera Inda Arfa
Published: June 2022

The main objective of this study is to determine the effect of return on assets and operating costs of income on the return on profit sharing from mudharabah deposits in Islamic commercial banks. The population and sample in this study are Islamic Banking Statistics (SPS) data, which includes statistics on Return on Assets, Operating Costs of Operational Income, and return on profit sharing from mudharabah deposits for Islamic Commercial Banks from January 2016 to December 2019. The results show that partial and simultaneous return on assets and operating costs of operating income have a positive and significant effect on return for the results of mudharabah deposits for Islamic Commercial Banks. However, the most dominant variable that has the greatest influence in this study is the operational cost of operating income.
The practice of Medical Laboratory Science Post-Act 857 era: Perceived role conflicts with ‘Laboratory Physicians’ and other scientists in Ghana
Authors: Adu-Gyasi Dennis
Published: June 2022

Medical Laboratory Science practice in Ghana faced several challenges at a period without regulation. In this era where the practice of the profession is regulated, turfs are being held to impede the development of medical laboratory professionals. In responding to the threat to the profession, the Medical Laboratory Science Professional Body in Ghana commissioned an expert committee to review what pertains to international practice. The committee was to proffer direction to the implementors of health policies in Ghana. The outcome of the committee’s work was disseminated as a position paper which is presented to the scientific community to inform of the autonomy of the medical laboratory science profession post regulatory era in Ghana.
A homoeopathic drug proving of Chamaeleo dilepis dilepis with a subsequent comparison of this remedy to those remedies yielding the highest numerical value and total number of rubrics on repertorisation of the proving symptoms
Authors:   , Moore Debora
Published: June 2022

The purpose of this investigation was to determine the effect of Chamaeleo dilepis dilepis on healthy volunteers (provers), and to record the signs and symptoms produced, so that it may be prescribed to those suffering from similar symptoms as determined by the Law of Similars. A further aim of the investigation was to compare the materia medica of Chamaleo dilepis dilepis as determined by proving symptoms to those remedies yielding the highest numerical value and total number of rubrics on repertorisation of the proving symptoms of Chamaeleo dilepis dilepis.
A prospective, epidemiological pilot study to investigate the level of knowledge of homoeopathy and its contextualization in health shops in the Gauteng area
Authors:   , Tatalias Janet Anne
Published: June 2022

Globally, complementary and alternative medicine is a rapidly expanding sector of which homeopathy and the sale of ‘over-the-counter’ homeopathic medicines is an integral part. In South Africa, the sale of homeopathic products in 2003 increased by 16.4% over figures for 2000. The sale of homeopathic medicines specifically, increased by 23% for the same period, and the sale of homeopathic medicines consists of 67% of all homeopathic products sold. The main method of distribution of these products is via retail outlets like health shops and pharmacies (Health Products Association, 2005). It is thus expected that health shop staff have a basic understanding of complementary therapies, including homeopathic medicines, due to the fact that these products are available ‘over-the-counter’ in health shops. To be effective health service providers, they are expected to understand the principles of homeopathy and its application via the available ‘over-the-counter’ homeopathic products. However, at best we can only assume the understanding that the health shop staff have. Thus, the level of understanding of homeopathy amongst health shop staff was examined through the use of a quantitative questionnaire.
An epidemiological study of selected risk factors associated with low back pain amongst refuse truck drivers in the eThekwini Municipality
Authors:   , Miosh S. Ramroop
Published: June 2022

Motivation: Lower back pain (LBP) has been found to affect workers and often result in higher costs to industry than any other musculoskeletal disorder. Traditionally, the most widely investigated risk factors for LBP have been biomechanical demands of the job. By examining LBP, both its prevalence and distribution, it becomes possible to focus on contributory risk factors that bring on its onset. Aim: To identify the selected risk factors associated with prevalence of LBP amongst refuse truck drivers in the eThekwini Municipality, and to evaluate the relationship between the selected risk factors and the prevalence of LBP.