bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship Between Mothers’ Role and Knowledge in Recurrence Prevention of Food Allergy for Children Under Five Years-Old
Authors: Rinawarti Fitria
Published: April 2018

There are 30-40% of people with allergies world wide in 2011, this is based on data from the Center for Disease Control and Prevention (CDC) more than tripled from 1993 to 2006. Parents play an important role in overcoming the recurrence of allergies in children in order of recurrence allergies and more severe recurrence. The goal of the study is to analyze association mothers’s role and knowledge in recurrence prevention of food allergy in children under five years-old. The study is an analytic observational research with cross sectional design. Method of sampling usedis simple random sampling. The samples were 39 mothers who have children under five years-old with food allergy in Rumah Sakit Islam Jemursari Surabaya. Analysis used chi-square test with α = 0.05 significance level.The results revealed the knowledge of mothers’ with allergy recurrance is 15 person (38,5%) have a good knowledge in prevention of food allergy in children under five years-old, while mothers’s role in recurrence prevention of food allergy in children under five years-old is 26 person (66,7%) have a role unfavorable. The statistical test by using chi-square revealed there were association between mothers’role (ρ=0,030) and mother’s of knowledge (ρ=0,00001)in recurrence prevention of food allergy for children under five years-old.The conclusions of the results this study is mothers’s role with unfavorable to have children under five years-old with an allergy recurrence of severe allergy, while mothers with good knowledge to have children under five years-old with an allergy reccurrance of mild allergy.Keywords: recurrence allergies, mother’s role, mother’s knowledge
The Association of Socioeconomic and Nutritional with Risk of Tuberculosis in DM Type 2 Patient
Authors: Fitri Pantaria Noor , Isfandiari Muhammad Atoillah
Published: April 2018

Diabetes mellitus (DM) is a diseases caused by less effective insulin use. East Java is the ten highest province for Diabetes prevalence all over Indonesia. DM patient risk higher for TB. This research aims to find out relationship between social-economy and nutrition status with TB occurrence to DM-type 2 sufferer in Kecamatan Tambaksari. This research is retrospective quantitative with case control design with age and sex corresponding. Sample of the research was counted by matching formula obtained out of 38 DM-TB sufferers for cases and 38 DM for control. Sample case and control were taken by simple random sampling. Characteristic result of DM and TB sufferers in Kecamatan Tambaksari 50% aged between 56–65 year. Amount of the sufferers 60,5% male. Education level is irrelated to the risk of TB occurrences in DM-type 2 sufferer, (p = 0.608 (> α= 0.05). Working status is related to the risk of TB occurrence to type 2 DM sufferer, (p = 0.022,OR = 3.2; 95%CI = 1.288-8.440). Waged level is related to the risk of TB occurrence to DM-type 2 sufferer, (p.= 0.009,OR = 13.214; 95%CI = 1,597-109.370). Nutrition status is related to TB occurrence to DM-type 2 sufferer, (p = 0.000, OR = 17.889; 95%CI = 4.653-68.772). The conclusion of this research is social economy factor, that is unemployed and wage < UMK, and nutrition status IMT < 18.5 related to TB occurrence to DM-type 2 sufferer. It needs to perform socialization for eating pattern regulation to DM-type 2 sufferer, TB screening to sufferer to DM-type 2 sufferer with nutrition status IMT < 18.5, and assistance for DM-type 2 with TB to have medical treatment routinely.Keywords: Tuberculosis, Diabetes Mellitus, socioeconomic, nutritional status
Response Optimization of a Chemical Gas Sensor Array Using Temperature Modulation
Authors: Durán Cristhian , Benjumea Juan
Published: April 2018

This paper consists in the design and implementation of a simple conditioning circuit to optimize the electronic nose performance, where a temperature modulation method was applied to the heating resistor, in order to study the sensor’s response and determine whether they are able to make the discrimination when are exposed to different Volatile Organic Compounds (VOC’s). This study was based on determining the efficiency of the gas sensors to be used in order to perform an Electronic Nose, improving the sensitivity, selectivity and repeatability of the measuring system and selecting the type of modulation (e.g. Pulse Width Modulation) for the analytes detection (i.e, Moscatel wine samples (2% of Alcohol) and Ethyl-Alcohol (70%)). The results demonstrated that using temperature modulation technique to the heater of sensors, it is possible to achieve a good discrimination of VOC's in fast and easy form, through a chemical sensors array. A discrimination model based on Principal Component Analysis (PCA) was implemented to each sensor, and data responses obtained gave a variance of 94.5% and 100% accuracy.
Seismic and Energy Renovation. A Review of the Design Approach in Italy and in Romania
Authors: Georgescu Emil-Sever , Georgescu Mihaela Stela , Macri Zina , Marino Edoardo Michele , Margani Giuseppe , Meita Vasile , Pana Radu , Petran Horia , Rossi Pier Paolo , Sapienza Vincenzo , Voica Marius
Published: April 2018

Most European cities are characterized by very large areas, often formed by buildings with low quality, from a series of point of view. The possibility of renovating them is strategic to improve both the quality of life and to the possibility of economic recovery for building companies. In the last decades, the attention of the scientific community has been addressed to the energy renovation, thanks to the strong activities of the European Community in this field. However, since a relevant part of the EC territory is at risk of earthquake, the possibility to combine both energy and seismic renovation actions may be strategic for many countries. In particular, Italy and Romania are linked by a common social tradition that springs from the Roman Empire. Nowadays, this link is stronger, thanks to common interests in social, cultural and business fields. Therefore, the investigation of possible synergies for seismic and energy renovation strategies may be really interesting for both countries. This paper represents the first step in this direction. After an overview of regulations and common practices for buildings with reinforced concrete structures, in both states, some key combined renovation interventions will be described and discussed, as well as advantages and perspectives of integrated renovation approaches.
Crowdfunding as an Alternative Means for Funding Sustainable Appropriate Technology—With a Focus on the Factors Determining the Acceptance of Backers
Authors: Moon Younghwan , Hwang Junseok
Published: April 2018

The R&D and propagation of sustainable appropriate technology requires the provision of stable funding. Crowdfunding is a form of funding whereby small sums of investments or contributions are collected from among the general public and used to finance the development of goods or services. This method has been in use widely in arts and culture fields, and presents a useful alternative means for funding appropriate technology projects. The aim of this study is to identify the factors influencing the backers who participate in appropriate technology projects through crowdfunding platforms, analyzing the relationships between these factors, and thereby establishing the usefulness of crowdfunding as a viable new alternative. The analysis results indicate that key factors influencing user intention to crowdfund appropriate technology projects include social influence, effort expectancy, and perceived trust. In contrast to the findings of previous studies, performance expectancy was not found to have a significant effect. This reflects the fact that, compared to the crowdfunding conducted for other purposes, crowdfunding for appropriate technology is closer in nature to donations. These findings indicate that for funding to be successful, aggressive online exposure using the SNS of backers should be pursued from the early stages of funding.
Effect of Massoia (Massoia aromatica Becc.) Bark on the Phagocytic Activity of Wistar Rat Macrophages
Authors: Hertiani Triana , Yuswanto Agustinus , Utami Tunjung Pratiwi Sylvia , Mashar Harlyanti
Published: April 2018

Massoia (Massoia aromatica Becc., Lauraceae) bark has been widely used as a component of traditional Indonesian medicine. The indigenous people boil or steam the bark for traditional applications. Our preliminary research revealed the potency of Massoia essential oil and its major compound, C-10 Massoialactone as potential immunomodulator in vitro. However, no scientific evidence regarding its in vivo effects is available. Therefore, this study evaluated the potential immunomodulatory effects of Massoia bark infusion on the nonspecific immune response (phagocytosis) of Wistar rats. The aqueous extract of Massoia bark was obtained by boiling pulverized bark in water, and the C-10 massoialactone content of the extract was determined through Thin Layer Chromatography (TLC) densitometry. For the in vitro assay, macrophages were treated with the freeze-dried infusion at the concentrations of 2.5, 5, 10, 20, or 40 μg/mL media. For the in vivo assay, 2-month-old male Wistar rats were divided into 5 groups. The baseline group received distilled water at the dose of 1 mL/100 g BW with the immunostimulant herbal product “X” administered as the positive control at the dose of 0.54 mL/rat. The treatment groups received the infusion at a dose of 100, 300, or 500 mg/100 g BW. Treatments were given orally every day for 14 days. The ability of macrophage cells to phagocyte latex was determined as phagocytic index (PI) and was observed under microscopy with 300 macrophages. The in vitro study revealed that the phagocytic activity of the infusion-treated macrophages significantly increased in comparison with that of the control macrophages in a concentration-dependent manner. Among all treatment concentrations, the concentration of 40 μg/ml provided the highest activity with a PI value of 70.51% ± 1.11%. The results of the in vivo assay confirmed those of the in vitro assay. The results of the present study indicate that Massoia bark can increase the phagocytic activity of rat macrophage cells. Its potential as a naturally derived immunomodulatory agent requires further study.
Comparison of the Plasma Temperature and Electron Number Density of Pulsed Electrolyte Cathode Atmospheric Pressure Discharge and Direct Current Solution Cathode Glow Discharge
Authors: Wang Jinmei , Li Shiyu , Zheng Peichao , Chen Yanying
Published: April 2018

A novel plasma source of pulsed electrolyte cathode atmospheric pressure discharge (pulsed-ECAD) driven by an alternating current (AC) power supply coupled with a high voltage diode was generated, and the discharge was generated in the open-to-air atmosphere between a metal electrode and a small-sized flowing liquid cathode. The spatial distribution of plasma temperatures (excitation, vibrational and rotational) of the pulsed-ECAD were investigated. The electron excitation temperature of H Texc(H), vibrational temperature of N2 Tvib(N2), and rotational temperature of OH Trot(OH) were measured as 4900±36-6800±108 K, 4600±86-5800±100 K and 1050±20-1140±10 K, respectively. Meanwhile, the temperature characteristics of dc solution cathode glow discharge (dc-SCGD) were also studied for comparison with pulsed-ECAD. The effects of operating parameters, including discharge voltage and discharge frequency, on the plasma temperatures were investigated. The electron number density determined in the discharge system and dc-SCGD were within the range (3.8–18.9) ×1014 cm-3 and 2.6×1014-17.2×1014 cm-3, respectively.
Microcirculatory Bloodstream Malfunctioning in Patients with Natural-Focal Infections
Authors: Grachieva O. V. , Sadretdinov R. A.
Published: April 2018

Represented are the results of examination of the 42 patients with Q-fever using laser Doppler flowmetry. Based on the data obtained identified are the skin microcirculatory disorders among the patients depending on their age, gender, severity of the disease, and occurrence of complications. Laser Doppler flowmetry predictors can be used for earlier diagnostics, prognostication, and prophylaxis of complications as well as evaluation of the efficacy as regards an ongoing therapy in Q-fever patients.
Сравнительная оценка балансного и синоптического методов определения ассимиляционной ёмкости водных экосистем
Authors: Асадов Х. Г. , Аскерова С. А.
Published: April 2018

Известно, что ассимиляционная емкость (АЕ) водной акватории определяется как максимальная динамическая вместимость такого количества загрязняющих веществ определённого вида, которое может быть за единицу времени накоплено, разрушено, трансформировано и выведено за пределы экосистемы при условии отсутствия нарушения её нормального функционирования. Статья посвящена сравнительному исследованию показателей АЕ, рассчитанных по балансному и синоптическому методам. Предложено геометрическое представление указанных сравниваемых методов в трёхмерном пространстве {Т, V, C}, где T — временной интервал, V — объём водной массы, C — концентрация загрязняющих веществ. Приведены количественные соотношения между двумя рассмотренными показателями АЕ. Полученные результаты применены к выбранным зонам акватории северной части прибрежной зоны азербайджанского сектора Каспийского моря. Показано, что для зимнего сезона значения ассимиляционной ёмкости, рассчитанные по синоптическому методу (Аc), несколько ниже, чем аналогичные показатели, рассчитанные по балансному методу (Ар), и составляют (0,6 ÷ 0,8) от Ар. Такой результат можно считать лучше известных результатов, в которых разница в оценках достигает одного порядка.
Response of Grain Legumes to Phosphorus Application in the Guinea Savanna Agro‐Ecological Zones of Ghana
Authors: Adjei‐Nsiah S. , Alabi B.U. , Ahiakpa J.K. , Kanampiu F.
Published: April 2018

Core Ideas

Rhizobium inoculation is effective in increasing soybean yields with little financial cost.

Grain legumes respond significantly to P‐fertilizer application in the savanna agro‐ecological zone of Ghana.

Promiscuous soybean responds well to inoculation in the savanna agro‐ecological zone of Ghana.

A significant number of smallholder farmers could benefit from application of rhizobium inoculants to soybean, both agronomically and economically.

Grain legumes (cowpea, peanut, and soybean) play important roles in household food and income security in smallholder farming systems in the Guinea Savanna agro‐ecological zones of Ghana. However, yields are low, rarely exceeding 600 kg ha−1, prompting the need to evaluate responses of grain legumes to P fertilizer applications for two seasons. Conducting P studies is critical to help farmers adopt economic‐based recommendations. Treatments evaluated in 2015 for the three crops were (i) farmers’ practice (no input and planted by farmer); (ii) control (no input and planted by researcher), and (iii) triple super phosphate (TSP) fertilizer. However, for soybean, an additional two treatments (inoculant only and inoculant plus TSP fertilizer) were included. In 2016, the treatments were the same, except on‐farm demonstrations were not conducted on cowpea. The demonstrations were laid out in a Randomized Complete Block Design with each demonstration representing a replicate within a region. On average, P‐fertilizer application increased yields by 296; 527, and 390 kg ha−1 for cowpea, peanut, and soybean grains, respectively. On average over the two seasons, P‐fertilizer increased yield by 9.85; 13.00, and 17.56 per kg ha−1 kg−1 P applied for cowpea, soybean, and peanut, respectively, and these applications were cost effective. Peanut showed little response to P in the Upper East Region compared with a greater response in the Northern and Upper West Regions, suggesting that benefits from P‐fertilizer for peanut may be location‐specific. On average, rhizobium inoculation increased grain yield by 157 kg ha−1 across the three regions and significantly positive effects of inoculation were observed in both seasons. Our results show that substantial increases in grain legume yield may be achieved by applying P fertilizers, but farmers cannot afford them because of their relatively high cost. Planting adapted and improved varieties and using rhizobium inoculants may provide the most economically viable and low risk options for increasing yields of grain legumes in the savanna agro‐ecological zones of Ghana
Phosphorus Leaching from Soil Cores from a Twenty‐Year Study Evaluating Alum Treatment of Poultry Litter
Authors: Anderson Kelsey R. , Moore Philip A. , Miller David M. , DeLaune Paul B. , Edwards Dwayne R. , Kleinman Peter J. A. , Cade‐Menun Barbara J.
Published: April 2018

Adding alum to poultry litter is a best management practice used to stabilize P in less soluble forms, reducing nonpoint‐source P runoff. However, little research has been conducted on how alum additions to litter affect subsequent leaching of P from soil. The objective of this study was to evaluate the effects of alum‐treated versus untreated poultry litter on P leaching from soil cores receiving long‐term poultry litter applications. Two intact soil cores were taken from each of 52 plots in a long‐term study with 13 treatments: a control, four rates each of untreated and alum‐treated litter (2.24, 4.49, 6.72, and 8.96 Mg ha−1), and four rates of ammonium nitrate (65, 130, 195, and 260 kg N ha−1). One core from each plot received the same fertilizer as for the previous 20 yr, whereas the other was unfertilized in the study year, resulting in a total of 25 treatments. Cores were exposed to natural rainfall, and P leaching was measured for 1 yr. The average soluble reactive P concentrations in the leachate varied from 0.16 to 0.44 mg P L−1 in fertilized alum‐treated cores, whereas leachate from cores fertilized with untreated litter ranged from 0.40 to 2.64 mg P L−1. At the highest litter rate (8.96 Mg ha−1), alum reduced total dissolved P and total P concentrations in leachate by 83 and 80%, respectively, compared with untreated litter. These results indicate that alum additions to poultry litter significantly reduced soluble and total P fractions in leachate.

Core Ideas

This study used soil cores from a 20‐yr small plot study.

Alum additions to poultry litter have a legacy effect on soil‐test P.

Soils fertilized with alum had significantly lower Mehlich‐3 P values below 10 cm.

Alum additions bind organic P in poultry litter and soil.

Total P leachate losses were reduced by 86% with alum.
Uso nocivo y potencial de abuso de la quetiapina. Reporte de caso y revisión de la evidencia
Authors: García Muñoz Erik
Published: April 2018

La quetiapina es un antipsicótico de segunda generación que tiene un amplio espectro de empleo en el tratamiento de varias enfermedades psiquiátricas, incluyendo a los trastornos por consumo de sustancias. A pesar de su eficacia y usos aprobados, hay varios informes de su potencial de abuso. En este artículo se reporta el primer caso en Hispanoamérica sobre uso riesgoso de quetiapina. Además, se incluye una revisión de la literatura que toma en cuenta reportes de caso, estudios epidemiológicos y estudios en modelos animales. El uso riesgoso o patrón de búsqueda-uso compulsivo de la quetiapina se reporta en individuos vulnerables con historial de trastornos por uso de sustancias, a menudo por consumo de cocaína. Se discuten las hipótesis sobre este fenómeno. A pesar de que la evidencia más fuerte de este tema procede de estudios preclínicos y no de mejores fuentes, los informes de casos como este deben ser tomados en cuenta en la evaluación de los pacientes, en cuanto a la utilidad de esta droga y sus posibles riesgos en el tratamiento de trastornos por uso de sustancias.
La incidencia del peritaje psicológico en la decisión judicial
Authors: Escobar Bedoya Estefanía , Granada de Espinal Luz Amparo
Published: April 2018

El presente artículo desarrolla fundamentalmente la importancia probatoria del peritaje, específicamente, del peritaje psicológico y su posterior incidencia en la decisión judicial en materia procesal. Para esto se tratarán los conceptos, sus particularidades, su repercusión como medio de prueba en un proceso jurídico, puesto que un correcto y verídico dictamen psicológico puede esclarecer los hechos. Así el juez podrá proferir una sentencia más justa, al considerar el análisis psicológico que le han dado los estudiantes de esta área a un tema que es tanto jurídico como psicológico. Por esto y por la naturaleza sobre derecho y sociedad del grupo de investigación Jurisol se realizará un acercamiento al tema con los estudiantes de Derecho y con los psicólogos en formación pertenecientes al semillero de derecho privado de la Universidad Católica Luis Amigó. Al tener un carácter interdisciplinario, el producto académico que presentamos tendrá mayor alcance para la investigación, gracias a los insumos que puede aportar para las áreas del Derecho y la Psicología que se unen y complementan aquí en un tema específico.
Aportes del constructivismo y la cultura matríztica a la terapia familiar sistémica
Authors: Valdés Gallego Ángela Viviana , Ruiz Garro Gloria Emilse , Restrepo Ríos July Andrea , Cardona Muñoz Lina María
Published: April 2018

El presente artículo contiene resultados de la revisión de la noción de matríztica y constructivismo en los postulados de Humberto Maturana y su relación con la Terapia Familiar Sistémica, desde un enfoque cualitativo con alcances hermenéuticos. La estrategia fue documental y la técnica de generación de información fue la revisión bibliográfica. La muestra correspondiente al análisis fue de diecisiete textos. La revisión documental arrojó categorías principales Matríztica vs Patriarcado y Lenguaje como fundamento de la construcción de lo humano. Evidenciándose así la importancia de éste último y la experiencia, en la construcción de los significados y las descripciones alternativas en el ámbito de la Terapia Familiar Sistémica.
Optimization, equilibrium and kinetic studies of Zn2+ and Ni2+ adsorption from aqueous solutions using composite adsorbent
Authors: Zwain Haider M. , Vakili Mohammadtaghi , Dahlan Irvan
Published: April 2018

A novel RHA/PFA/CFA composite adsorbent was synthesized from rice husk ash (RHA), palm oil fuel ash (PFA), and coal fly ash (CFA) by modified sol-gel method. Effect of different parameters such as adsorbent dosage, contact time, and pH were studied using batch experiment to optimize the maximum zinc (Zn2+) and nickel (Ni2) adsorption conditions. Results showed that the maximum adsorption condition occurred at adsorbent amount of 10 g/L, contact time of 60 min, and pH 7. At this condition, the removal efficiencies were 81% and 61% for Zn2+ and Ni2+, in which the adsorption capacities (qmax) were 21.74 mg/g and 17.85 mg/g, respectively. Adsorption behavior of RHA/PFA/CFA composite adsorbent was studied through the various isotherm models at different adsorbent amounts. The results indicated that the Freundlich isotherm model gave an excellent agreement with the experimental conditions. Based on the results obtained from the kinetic studies, pseudo-second-order was suitable for the adsorption of Ni2+ and Zn2+, compared to the pseudo-first-order model. The results presented in this study showed that RHA/PFA/CFA composite adsorbent successfully adsorbed Zn2+ and Ni2.
Climate change mitigation and adaptation in agriculture: the case of the olive
Authors: Montanaro G. , Nuzzo V. , Xiloyannis C. , Dichio B.
Published: April 2018

Agriculture might serve as a mitigation solution through carbon (C) sequestration in soil, in tree biomass and reducing greenhouse gas (GHG) emissions. Increased C is beneficial for some soil structures and functions, improving the use of water and in turn the crop adaptation. This study reports on the synergy between mitigation and adaptation in agriculture through the paradigm of the olive (Olea europaea). Through data on net ecosystem productivity and soil respiration, the role of olive groves to store C in tree biomass (from 0.36 to 2.78 t CO2 ha−1 yr−1) and into soil (∼8.5 t CO2 ha−1 yr−1) is reviewed. The influence of some management practices on that role is also discussed. The overall climatic impact of olive fruit and oil production has been evaluated also considering GHG emissions by field operations (e.g., pruning, mulching of cover crop, fertilization, harvest, etc.) and by the extraction and bottling of oil. Soil C as interface between climate change mitigation and adaptation has been delineated, linking C-induced improvements in soil properties to increased water storage and reduced run-off and erosion. The outcomes may strengthen the environmental role of agriculture and promote synergistic mitigation and adaptation policies assisting in soil and water resources conservation.
Porous PVDF/PANI ion-exchange membrane (IEM) modified by polyvinylpyrrolidone (PVP) and lithium chloride in the application of membrane capacitive deionisation (MCDI)
Authors: Zhang Yiming , Zhang Wei , Cházaro-Ruiz Luis F.
Published: April 2018

In this work, polyvinylidene fluoride (PVDF)/polyaniline (PANI) heterogeneous anion-exchange membranes filled with pore-forming agents polyvinylpyrrolidone (PVP) and lithium chloride were prepared by the solution-casting technique using the solvent 1-methyl-2-pyrrolidone (NMP) and a two-step phase inversion procedure. Key properties of the as-prepared membranes, such as hydrophilicity, water content, ion exchange capacity, fixed ion concentration, conductivity and transport number were examined and compared between membranes in different conditions. The pore-forming hydrophilic additives PVP and lithium chloride to the casting solution appeared to improve the ion-exchange membranes (IEMs) by increasing the conductivity, transport number and hydrophilicity. The effects of increasing membrane drying time on the porosity of the as-prepared membranes were found to lower membrane porosity by reducing membrane water content. However, pore-forming agents were found to be able to stabilise membrane transport number with different drying times. As-prepared PVDF/PANI anion-exchange membrane with pore-forming agent is demonstrated to be a more efficient candidate for water purification (e.g. desalination) and other industrial applications.
Curcumin as an Adjunct Therapy and microRNA Modulator in Breast Cancer
Authors: Norouzi Saeed , Majeed Muhammed , Pirro Matteo , Generali Daniele , Sahebkar Amirhossein
Published: April 2018

Background:

Pathogenesis of breast cancer is paralleled by distinct alterations in the expression profile
of several microRNAs (miRNAs). Recent studies have shown that miRNAs can serve as diagnostic and prognostic
markers, and also as therapeutic targets in breast cancer. Curcumin is a biologically active dietary polyphenol
that has emerged with strong anti-tumor properties that are also documented in breast cancer.

Methods:

A multi-database electronic search was performed to provide an overview of curcumin as an adjunct
therapy and miRNA modulator in breast cancer and highlight the significance of observations for the treatment of
cancer therapies.

Results:

The putative anti-tumor properties of curcumin are mediated by diverse mechanisms including inhibition
of cell proliferation, metastasis, migration, invasion and angiogenesis, and induction of G2/M cell cycle arrest,
apoptosis and paraptosis. Recent evidence implies that curcumin can interact with several oncogenic and tumorsuppressive
miRNAs involved in different stages of breast cancer. In this context, up-regulation of miR181b,
miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown
following the treatment of several breast cancer cell lines with curcumin. These effects lead to the suppression of
tumorigenesis and metastasis, and induction of apoptosis.

Conclusion:

Curcumin appears as an important miRNA modulator in breast cancer. However, further investigations
are warranted to elucidate the impact of curcumin on miRNA transcriptome profile of breast cancer and the
resulting impact of experimental models.
A Very Rare Cause of Lower Limb Ischemia in Young People: Popliteal Artery Entrapment
Authors: Altinsoy Hasan Baki , Alatas Ozkan , Khalil Emjed , Kara Kenan Abdurrahman , Okten Candan Cudi , Dogan Omer Faruk
Published: April 2018

Background:

Popliteal artery entrapment syndrome (PAES) is a very rare pathology that can cause lower extremity ischemia in healthy young people. Anomalous anatomic relationships between the popliteal artery (PA) and the surrounding musculo-tendinous structures cause PAES. We present 31 patients with PAES in 35 limbs that were treated surgically in our clinic within a 12-year period.

Patients and Methods:

From 2001 to 2015, 31 patients (mean age: 32 ± 7.4 years) underwent surgery for PAES. ; 4 patients presented had bilateral PAES. Doppler ultrasonography (US), magnetic resonance angiography (MRA), and conventional angiography were performed as diagnostic procedures. We detected Type I PAES in 4 limbs and Type II PAES in 12 limbs. In the remaining 19 limbs, we diagnosed Type III or Type IV PAES. Simple release of the PA, PA embolectomy and simple release, and the radial artery (RA) patch angioplasty, with or without thromboendarterectomy (TEA), were performed. In 12 limbs, PA continuity was provided by RA interposition.

Results:

With the exception of 5 patients, no complications were seen after surgery. Haematoma was detected in 2 patients and local infection in 2 patients. One patient required a revision for recurrent PA thromboembolic event 12 h after surgery. At a median follow- up of 23 months (range: 11-29 months), there were no postoperative complications.

Conclusions:

PAES can result in lower limb ischemia due to chronic vascular trauma in young healthy patients. The use of diagnostic tools such as US, a non-invasive method, and MRA are effective diagnostic tools for early diagnosis. With their combined approach, exact and early diagnosis can be achieved. PA release, alone or with arterial bypass using RA, is a viable treatment option when intervention is necessary to prevent limb loss in the early stages of the disease.
Síntesis in‐situ, caracterización, evaluación antibacterial y nanotoxicológica de cueros sintéticos de cloruro de polivinilo conteniendo nanopartículas de cobre (PVC/NPsCU 0 )
Authors: Salazar Robert , Aquino Myshell , Alvarez Y.
Published: April 2018

Agentes capaces de transmitir enfermedades como las bacterias, virus y hongos son los principales causantes de las infecciones intrahospitalarias (IIH) en el mundo, esto ha motivado el desarrollo de los Nuevos Materiales basados en la Nanotecnología, donde en una rama de este se sintetizan nanocompósitos antibacteriales del tipo: Polímero/Metal Antibacterial, sintetizando superficies con gran actividad inhibidora de bacterias. En el presente trabajo, se han generado nanocompósitos poliméricos antibacteriales, preparando el Policloruro de Vinilo (PVC) de resina en emulsión como plastisol y sintetizando nanopartículas de Cobre dentro de la matriz polimérica (in‐situ). La descripción de la metodología se da con la síntesis de un precursor de Cobre para posterior dispersión mediante pulsos ultrasónicos, posterior estabilización y mezclado con los aditivos del PVC para posterior reducción química durante el gelificado de los plastisoles. El análisis espectral de los laminados de PVC/NPsCu0 por medio de Fluorescencia de Rayos X en Energía Dispersiva (FRX‐ED), utilizando el software específico PyMca 4.7.4, revelan que la importancia del tiempo de gelificación del PVC guarda relación con el grado de reducción del Ácido Ascórbico (AA) sobre el Cu2+. Por otro lado, resultados del análisis por Espectroscopia Electrónica de Barrido (MEB) revelan que las dimensiones de las NPsCu0 varían en un rango de 50 a 250 nm. Los patrones de difracción de Rayos X (DR‐X) evidencian la parcial cristalización polimérica del PVC y la presencia de Cu0. Se confirmó la actividad antibacteriana de los laminados de PVC/NPsCu0 por el método de difusión de disco sobre Eschericcia coli O157:H7; el halo de inhibición promedio resultó ser de 9,7 mm que implica un significativo efecto bactericida sobre la cepa mencionada. La viabilidad del desarrollo de estos nanocompósitos poliméricos se estudió por medio de un ensayo nanotoxicológico mediante el análisis citotóxico de los nanocompósitos de PVC/NPsCu0 en células de sangre periférica humana, concluyendo que dicho efecto citotóxico sobre células sanas es menor al 8%. La viabilidad del desarrollo de estos nanocompósitos poliméricos se estudió por medio de un ensayo nanotoxicológico mediante el análisis citotóxico de los nanocompósitos de PVC/NPsCu0 en células de sangre periférica humana, concluyendo que dicho efecto citotóxico sobre células sanas es menor al 8%.
Implementación de un robot móvil para optimizar el flujo documentario en el área de logística usando tecnologías de robótica autónoma basada en la plataforma de software libre ROS
Authors: Calle Flores Iván , Paredes Maraza Rider V. , Bazan Yaranga Cristopher , Guardia Guizado Aldo A.
Published: April 2018

El presente proyecto consistió en la implementación de un robot móvil autónomo capaz de facilitar el flujo de documentos entre las diferentes áreas de una empresa, universidad, etc. Este robot es capaz de navegar de manera completamente autónoma en ambientes reales tal como los ambientes del CTIC, FIM, FIEE, etc. Tan solo especificando el punto inicial, el mapa del ambiente de navegación, y el punto deseado, este robot es capaz de generar el camino óptimo para llegar a dicha meta, y luego seguir este camino con la capacidad de evitar obstáculos si estos se presentan. Dadas estas características, este robot se puede usar en aplicaciones logísticas en donde el robot debe llevar paquetes, cargas, etc., a algún punto especificado por el usuario. En el proyecto se tienen dos modelos, el primer robot llamado R2D2‐R1 puede llevar cargas de hasta 3kg, y el segundo robot llamado R2D2‐R2 puede llevar cargas de hasta 25kg. Cabe señalar que los algoritmos implementados en este proyecto representan el estado del arte del campo de la robótica autónoma, y su desempeño se ha comprobado en las diversas pruebas de navegación realizadas en ambientes de la UNI. Este proyecto contribuye a cumplir con la misión de la UNI en los temas de innovación y gestión tecnológica para contribuir al bienestar de la sociedad y desarrollo del país.
“Security Union” and the digital sphere: unpacking securitization processes
Authors: Fernandes Sandra
Published: April 2018

Since 2016, the EU is boosting its agenda on security in a geopolitical context that comprises multiple challenges, namely the fight against terrorism, the migration pressure, relations with Russia, Brexit, and the redefinition of the Euro-Atlantic partnership. This article exposes drivers of the EU’s perspective on security, in particular, in the context of the “Security Union” framework and the emergence of the digital sphere as a defence matter.
Testing a Web-Based Interactive Comic Tool to Decrease Obesity Risk Among Minority Preadolescents: Protocol for a Pilot Randomized Control Trial (Preprint)
Authors: Leung May May , Mateo Katrina F , Verdaguer Sandra , Wyka Katarzyna
Published: April 2018

BACKGROUND

Childhood obesity is a public health crisis, particularly in low-income, minority populations in the United States. Innovative and technology-enhanced interventions may be an engaging approach to reach at-risk youth and their parents to improve dietary behaviors and feeding practices. However, such tools are limited, especially ones that are theory-based; co-developed with user-centered approaches; tailored to low-income, minority preadolescents; and include parent-focused content.

OBJECTIVE

The objectives of this study include assessing the feasibility and acceptability and exploring the potential impact of the Intervention INC (Interactive Nutrition Comics for urban, minority preadolescents) Web-based tool, which is focused on decreasing childhood obesity risk in black/African American and Latino children aged 9 to 12 years.

METHODS

Intervention INC is underpinned by the narrative transportation theory, social cognitive theory, and health belief model, and it was co-developed by children and parents from the intended population. The child component consists of a 6-chapter interactive nutrition comic optimized for use on tablet devices, a goal-setting and self-assessment feature, and weekly text/email messages and reminders. The parental component consists of 6 Web-based newsletters, access to the child comic, and weekly text/email messages and reminders. The tool was evaluated using a pilot, single-blind, 2-group randomized controlled study design. Child-parent dyads were randomized to either the experimental or comparison group and assigned to a targeted behavior (increase fruit/vegetable or water intake) based on initial screening questions. Data were collected at 4 time points: baseline (T1), intervention midpoint (T2), intervention endpoint (T3), and 3 months postintervention (T4). Primary measures comprise usage, usability, and feasibility of the Web-based tool. Secondary measures comprise dietary knowledge, preferences, and intake and anthropometric measures (for child) and feeding practices and home food environment (for parent).

RESULTS

Study enrollment was completed in November 2017. A total of 89 child-parent dyads were randomized to either the experimental (n=44) or comparison (n=45) group. Data analysis is currently being conducted.

CONCLUSIONS

This study aims to implement and assess an innovative approach to deliver health messages and resources to at-risk minority preadolescents and their parents. If found to be acceptable, engaging, feasible, and a potential approach to improve dietary behaviors, a full-fledged randomized controlled trial will be conducted to assess its efficacy and potential impact.

CLINICALTRIAL

ClinicalTrials.gov NCT03165474; https://clinicaltrials.gov/ct2/show/NCT03165474 (Archived by WebCite at http://www.webcitation.org/73122IjgP)

INTERNATIONAL REGISTERED REPOR

RR1-10.2196/10682
Patient-Physician Communication in the Era of Mobile Phones and Social Media Apps: Cross-Sectional Observational Study on Lebanese Physicians� Perceptions and Attitudes (Preprint)
Authors: Daniel Fady , Jabak Suha , Sasso Roula , Chamoun Yara , Tamim Hani
Published: April 2018

BACKGROUND

The increased prevalence of virtual communication technology, particularly social media, has shifted the physician-patient relationship away from the well-established face-to-face interaction. The views and habits of physicians in Lebanon toward the use of online apps and social media as forms of patient communication have not been previously described.

OBJECTIVE

The aim of this study is to describe the views of Lebanese physicians toward the use of social media and other online apps as means of patient communication.

METHODS

This was a cross-sectional observational study using an online survey that addressed physicians’ perceptions on the use of virtual communication in their clinical practice. The study took place between April and June 2016, and was directed toward physicians at the American University of Beirut Medical Center.

RESULTS

A total of 834 doctors received the online survey, with 238 physicians completing the survey. Most of the participants were from medical specialties. Most responders were attending physicians. Less than half of the respondents believed that Web-based apps and social media could be a useful tool for communicating with patients. Email was the most common form of professional online app, followed by WhatsApp (an instant messaging service). The majority of participants felt that this mode of communication can result in medicolegal issues and that it was a breach of privacy. Participants strictly against the use of virtual forms of communication made up 47.5% (113/238) of the study sample.

CONCLUSIONS

The majority of physicians at the American University of Beirut Medical Center are reluctant to use virtual communication technology as a form of patient communication. Appropriate policy making and strategies can allow both physicians and patients to communicate virtually in a more secure setting without fear of breaching privacy and confidentiality.
Design of Electronic Mass Balance of Gram Scale Using a Gage Strain Sensor
Authors: Sulistyanto Muhammad Priyono Tri , Pranata Kurriawan Budi , Endarko Endarko , Muntini Melania Suweni
Published: April 2018

This research is conducted by utilizing strain gage uniaxial sensor with internal resistance 120 ohms and brass cantilever beam that is to build electronic mass scale in gram level. Basically, the aim of this research is to study deflect phenomenon measured by the strain gage sensor attached in the end of brass cantilever beam. Brass material was chosen to build cantilever as its Young moudulus contanst is bigger than other materials. Whilst mass loads for analizing brass cantilever profile are calibrated by manual Ohaus mass scale (PA214 type) with 0.07 gram load variations. The test result of this electronic mass scale system gets relationship of mass load data variation versus output voltage data (from differential amplifier). The relationship between mass and voltage can be approached by polynomial formula m = 4.2372V2 – 2.4551V + 1.5606 where m in gram and V in volt, and it gets 0.07 or 7% average error (less than linear formula approach). This formula is used further for programming ADC in 8-bit microcontroller to calculate mass and the calculation is shown in LCD 16x2.
Pengaruh Adaptasi Waktu Administrasi yang disebabkan Penggunaan Lembar Jawaban Komputer terhadap Hasil CFIT 3 A dan 3 B
Authors: Saptoto Ridwan
Published: April 2018

Previous research showed difference in intelligence level caused by difference in answering method. This research aimed to adapt test time administered using computer answer sheet. Adaptation time was conducted by comparing time needed to give answer by making cross line and blackening answer dots using 2B computer pencil. Experiment method with two independent group design had chosen. Data analysis showed no difference in raw score between control group and experiment group in CFIT 3A (t = 1.045, p > 0.05), CFIT 3B (t = 0.368, p > 0.05), and CFIT 3A and 3B (t = 0.791, p > 0.05). Data analysis also found no difference in intelligence level between both groups in CFIT 3A (t = 1.063, p > 0.05), CFIT 3B (t = 0.470, p > 0.05), and CFIT 3A and 3B (t = 0.771, p > 0.05). Adaptation administration time did not change intelligence test results.  Abstrak.Hasil penelitian sebelumnya menunjukkan adanya perbedaan tingkat inteligensi yang disebabkan oleh perbedaan metode memberikan jawaban. Penelitian ini bertujuan melakukan adaptasi terhadap tes yang menggunakan lembar jawaban komputer. Adaptasi waktu dilakukan dengan membandingkan waktu yang dibutuhkan untuk memberikan jawaban dengan cara menyilang dan menghitamkan alternatif jawaban menggunakan pensil 2B. Metode eksperimen dengan desain dua kelompok independen dipilih dalam penelitian ini. Analisis data menunjukkan tidak terdapat perbedaan skor mentah antara kelompok kontrol dan kelompok eksperimen pada CFIT 3A (t = 1,045, p > 0,05), CFIT 3B (t = 0,368, p > 0,05), serta CFIT 3A dan 3B (t = 0,791, p > 0,05). Analisis data juga menemukan tidak terdapat perbedaan tingkat inteligensi antara kedua kelompok pada CFIT 3A (t = 1,063, p > 0,05), CFIT 3B (t = 0,470, p > 0,05), serta CFIT 3A dan 3B (t = 0,771, p > 0,05). Adaptasi waktu administrasi tidak mengubah hasil tes inteligensi.
RESPON PRIMIPARA SAAT DIPUTUSKAN SECTIO CAESAREA DARURAT
Authors: Sari Febria Syafyu
Published: April 2018

Primipara yang akan menjalani persalinan secara Sectio Caesarea (SC) dapat mempengaruhi  kesiapan praoperatif saat diputuskan SC. Ketidaksiapan primipara dalam menghadapi praoperatif SC dapat meningkatkan resiko depresi postpartum. Penelitian kualitatif dengan pendekatan desain fenomenologi deskriptif yang bertujuan untuk mengeksplorasi respon pertama kali primipara pada praoperatif SC. Penelitian ini dilaksanakan pada tahun 2016 di ruang Kebidanan, dengan jumlah partisipan sebanyak enam orang yaitu enam pasien SC darurat. Hasil penelitian ini dianalisis menggunakan metode Collaizi. Etika yang diperhatikan dalam penelitian ini dengan menghormati prinsip etik penelitian dan keabsahan data memperhatikan kriteria: credibility, transferability, dependability dan confirmability. Didapatkan hasil penelitian yaitu respon fisik dan psikologis. Hasil penelitian ini dapat disimpulkan bahwa hampir keseluruhan partisipan  mengalami kecemasan. Partisipan berusaha mendekatkan diri pada Tuhan, berdoa dan berserah diri  sehingga tidak terbentuk koping yang mal adaptif.  Saran untuk petugas kesehatan dapat melakukan asuhan keperawatan psikososial sehingga dapat menanamkan kepercayaan kepada ibu yang akan melakukan persalinan SC dan dapat  menurunkan kecemasan

 

Primiparas who will undergo cesarean delivery by Caesarea (CS) may affect preoperative preparedness when the CS is decided. Primiparous unpreparedness in the face of preoperative CS may increase the risk of postpartum depression. Qualitative research with descriptive phenomenology design approach aimed to explore primitive experience on CS preoperative. The study was conducted in January - July 2016 in Midwifery room, with six participants, six emergency CS patients. The results of this study were analyzed using the Collaizi method. Ethics is considered in this study with respect to the principles of research ethics and data validity pay attention to the criteria: credibility, transferability, dependability and confirmability. The result of this research is perception to CS. The results of this study can be concluded that participants perceive CS which is a frightening invasive action that will endanger the safety of mother and fetus .. Suggestions for mothers can be the next learning in the face of labor by looking at experience in facing preoperative emergency CS
Impact and Reception of a Required 4-Week Palliative Medicine Rotation
Authors: Simmons B. Brent , Petrie Alison , Gracely Edward
Published: April 2018

Background and Objectives: Hospice and palliative medicine (HPM) is one of three Accreditation Council for Graduate Medical Education accredited clinical subspecialties available to family medicine graduates for fellowship training. Despite this, training is not currently a curriculum requirement. We have pioneered a required 4-week palliative medicine rotation into the curriculum.
Methods: Twenty-eight residents who completed the palliative medicine rotation across four classes were surveyed to assess how the rotation improved their level of comfort with providing end-of-life (EOL) care and to demonstrate the need of formal palliative medicine training. Wilcoxon signed ranks test was used to detect statistical differences between the mean level of comfort of residents pre- and postrotation with providing the basic skills needed to practice HPM.
Results: The HPM rotation significantly improved the residents’ level of comfort in all areas of measured EOL care (P<0.001). All residents surveyed strongly agreed that the rotation was valuable to their future and 100% of residents strongly agreed that an HPM rotation should be required.
Conclusions: Formal HPM training should be a required component in residency education and considerations should be given to the 4-week format. This rotation provides a model that can be implemented in other residency programs nationally. Implementation of this rotation may help close the enormous gap of patients not receiving quality EOL care.
Pengelola Jurnal
Authors: Jurnal Pengelola
Published: April 2018

Pengelola Jurnal