bluuebunny/crossref_metadata_2025 huggingface dataset:
Towards SDGs 4 and 8: How Value Co-Creation Affecting Entrepreneurship Education’s Quality and Students’ Entrepreneurial Intention
Authors: Walidayni Carissa Tibia , Dellyana Dina , Chaldun Evy Rachmawati
Published: March 2023

Vocational high school (VHS) is a formal education designed to equip students with ready-to-use industrial skills upon graduation. However, its graduates continue to dominate the Open Unemployment Rate, despite the Indonesian government’s efforts to incorporate entrepreneurship education into the VHS curriculum. The premise of education as a service with students as the customers has inspired this research to study the phenomena of entrepreneurship education in VHS from the Service–Dominant Logic perspective. This study aimed to investigate the direct effect of students’ value co-creation on their entrepreneurial intention and the mediating role of the quality and satisfaction of entrepreneurship education. The PLS-SEM method was applied to analyze 202 samples of VHS students from 13 administrative regions within West Java Province, Indonesia. It was found that students’ value co-creation in entrepreneurship education significantly affected the education quality and students’ entrepreneurial intention. However, the mediating role of students’ satisfaction was significantly influenced by education quality and value co-creation only, while satisfaction itself could not influence entrepreneurial intention. These findings are expected to be considered by the government and VHS to further involve the students in value co-creation since it can enhance the quality of entrepreneurship education and, thus, students’ interest in becoming entrepreneurs. The results of this study are committed towards the SDG 4 and 8’s initiatives to provide quality education in order to boost entrepreneurship for economic growth.
Avoiding “Paper Parks”: A Global Literature Review on Socioeconomic Factors Underpinning the Effectiveness of Marine Protected Areas
Authors: Di Cintio Antonio , Niccolini Federico , Scipioni Sara , Bulleri Fabio
Published: March 2023

Marine protected areas (MPAs) are a common management tool for preserving marine biodiversity and halting resource depletion. Despite the number of MPAs rapidly increasing worldwide, there are concerns over the full achievement of their objectives. Indeed, in some cases—the phenomenon of so-called “paper parks”—protected areas totally fail to achieve their conservation and socioeconomic targets. Therefore, identifying the factors underpinning MPA success or failure is crucial to increase their effectiveness. To achieve this goal, we performed a global literature review on the socioeconomic factors that managers should pursue to enhance MPA effectiveness on a global scale. A search of the Scopus database, using strings of keywords connected by Boolean operators, generated a batch of 715 items, out of which 68 were retained after the application of inclusion/exclusion criteria. Six other articles were added through the scanning of the literature cited in selected papers. We grouped MPA success-factors into 13 main groups and ranked them according to the frequency of citation in the literature. Our findings identify stakeholder involvement, increasing communication and awareness between specific stakeholder groups, as well as ensuring appropriate enforcement and monitoring, control and surveillance, as the leading factors for MPA success. Our results will assist in the process of upcoming global expansion of MPAs, thus contributing to improving conservation of marine biodiversity and associated livelihoods.
A Simulation-Based Optimization Model for Control of Soil Salinization in the Hetao Irrigation District, Northwest China
Authors: Zhang Yunquan , Yang Peiling
Published: March 2023

The average annual water diversion of the Hetao Irrigation District (HID) from the Yellow River is 4.5 billion cubic meters, mainly used for surface irrigation. Because the groundwater depth is shallow, strong evaporation conditions and unmatched irrigation conditions lead to serious soil salinization in the area; thus, the irrigation area’s ecological environment is fragile. Based on the current situation of the Yellow River irrigation project in the area, an interval two-stage robust stochastic optimization model is proposed to address the problem. In 2015, the Shuguang Experimental Station in the middle of the HID, Inner Mongolia, discussed the impact of different degrees of water–salt coordinated regulation on water consumption, yield and price of wheat, maize and sunflower under drip irrigation conditions. The obtained results provide the water shortage and water distribution targets of multiple water sources and multiple water levels in five irrigation areas of the HID. Those water distribution targets were used as the main input parameter and entered into the SALTMOD model based on the principle of water and salt balance. The output included data on groundwater mineralization and groundwater depth. It was observed that (1) integrated interval two-stage robust stochastic programming and the SALTMOD Model to couple optimization model under uncertainty can simulate a model together; (2) systemic risk issues were considered; and (3) the proposed method can be applied to the HID in northwest China to solve the soil salinization control problem. This approach is applicable to arid and semiarid regions that face similar problems.
Comparative Analysis of Spectroscopic Studies of Tungsten and Carbon Deposits on Plasma-Facing Components in Thermonuclear Fusion Reactors
Authors: Stankevich Vladimir G. , Svechnikov Nickolay Y. , Kolbasov Boris N.
Published: March 2023

Studies on the erosion products of tungsten plasma-facing components (films, surfaces, and dust) for thermonuclear fusion reactors by spectroscopic methods are considered and compared with those of carbon deposits. The latter includes: carbon–deuterium CDx (x ~ 0.5) smooth films deposited at the vacuum chamber during the erosion of the graphite limiters in the T-10 tokamak and mixed CHx-Me films (Me = W, Fe, etc.) formed by irradiating a tungsten target with an intense H-plasma flux in a QSPA-T plasma accelerator. It is shown that the formerly developed technique for studying CDx films with 15 methods, including spectroscopic methods, such as XPS, TDS, EPR, Raman, and FT-IR, is universal and can be supplemented by a number of new methods for tungsten materials, including in situ analysis of the MAPP type using XPS, SEM, TEM, and probe methods, and nuclear reaction method. In addition, the analysis of the fractality of the CDx films using SAXS + WAXS is compared with the analysis of the fractal structures formed on tungsten and carbon surfaces under the action of high-intensity plasma fluxes. A comparative analysis of spectroscopic studies on carbon and tungsten deposits makes it possible to identify the problems of the safe operation of thermonuclear fusion reactors.
Numerical Method for Solving Fractional Order Optimal Control Problems with Free and Non-Free Terminal Time
Authors: Al-Shaher Oday I. , Mahmoudi M. , Mechee Mohammed S.
Published: March 2023

The optimal control theory in mathematics aims to study the finding of control for a dynamic system over time, where an objective function is optimized. It has a broad range of applications in engineering, operations research, and science. The main purpose of this study is to provide numerical algorithms for two cases of optimal control problems of fractional order that involve fractional order derivatives with free and non-free terminal time. In addition to comparing the numerical results for three test problems with exact solutions of these problems, various computer simulations are also introduced.
Deep Reinforcement Learning Reward Function Design for Autonomous Driving in Lane-Free Traffic
Authors: Karalakou Athanasia , Troullinos Dimitrios , Chalkiadakis Georgios , Papageorgiou Markos
Published: March 2023

Lane-free traffic is a novel research domain, in which vehicles no longer adhere to the notion of lanes, and consider the whole lateral space within the road boundaries. This constitutes an entirely different problem domain for autonomous driving compared to lane-based traffic, as there is no leader vehicle or lane-changing operation. Therefore, the observations of the vehicles need to properly accommodate the lane-free environment without carrying over bias from lane-based approaches. The recent successes of deep reinforcement learning (DRL) for lane-based approaches, along with emerging work for lane-free traffic environments, render DRL for lane-free traffic an interesting endeavor to investigate. In this paper, we provide an extensive look at the DRL formulation, focusing on the reward function of a lane-free autonomous driving agent. Our main interest is designing an effective reward function, as the reward model is crucial in determining the overall efficiency of the resulting policy. Specifically, we construct different components of reward functions tied to the environment at various levels of information. Then, we combine and collate the aforementioned components, and focus on attaining a reward function that results in a policy that manages to both reduce the collisions among vehicles and address their requirement of maintaining a desired speed. Additionally, we employ two popular DRL algorithms—namely, deep Q-networks (enhanced with some commonly used extensions), and deep deterministic policy gradient (DDPG), which results in better policies. Our experiments provide a thorough investigative study on the effectiveness of different combinations among the various reward components we propose, and confirm that our DRL-employing autonomous vehicle is able to gradually learn effective policies in environments with varying levels of difficulty, especially when all of the proposed rewards components are properly combined.
What Makes a Good Critical Literature Review Paper?
Authors: Garrod Brian
Published: March 2023

Literature review papers are highly influential in directing academic discourse, not only because they map the state of the art in a subject area, but also because they show future research prospects by identifying weaknesses, limitations, and gaps in the extant body of knowledge on a particular subject [...]
Immunotoxicity of Three Environmental Mycotoxins and Their Risks of Increasing Pathogen Infections
Authors: Sun Yuhang , Song Yuqi , Long Miao , Yang Shuhua
Published: March 2023

Aflatoxin B1 (AFB1), ochratoxin A (OTA), and deoxynivalenol (DON) are the three mycotoxins that have received the most scholarly attention and have been tested most routinely in clinics. These mycotoxins not only suppress immune responses but also induce inflammation and even increase susceptibility to pathogens. Here, we comprehensively reviewed the determining factors for the bidirectional immunotoxicity of the three mycotoxins, their effects on pathogens, and their action mechanisms. The determining factors include mycotoxin exposure doses and times, as well as species, sex, and some immunologic stimulants. Moreover, mycotoxin exposure can affect the infection severity of some pathogens, including bacteria, viruses, and parasites. Their specific action mechanisms include three aspects: (1) mycotoxin exposure directly promotes the proliferation of pathogenic microorganisms; (2) mycotoxins produce toxicity, destroy the integrity of the mucosal barrier, and promote inflammatory response, thereby improving the susceptibility of the host; (3) mycotoxins reduce the activity of some specific immune cells and induce immune suppression, resulting in reduced host resistance. The present review will provide a scientific basis for the control of these three mycotoxins and also provide a reference for research on the causes of increased subclinical infections.
Host-Specific Interplay between Foot-and-Mouth Disease Virus 3D Polymerase and the Type-I Interferon Pathway
Authors: Sarry Morgan , Caignard Grégory , Dupré Juliette , Zientara Stephan , Vitour Damien , Bakkali Kassimi Labib , Blaise-Boisseau Sandra
Published: March 2023

Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals. One of the issues related to this disease is the persistence of its causative agent, foot-and-mouth disease virus (FMDV). While the mechanisms of FMDV persistence remain unclear, there are clues that it may be related to protein–protein interactions (PPI) between viral proteins and cellular proteins involved in the interferon (IFN) response. Since FMDV persistence has been described in cattle, sheep and goats but not in swine, we screened PPI involving FMDV proteins and sixteen major type-I IFN pathway proteins from these four species by nanoluciferase-2-hybrid complementation assay, in order to identify new PPI and determine their host specificity. As the results concerning the 3Dpol were the most interesting in view of the limited data concerning its role in immune escape, we decided to focus particularly on this protein. The identified PPI were confirmed by GST pull-down. We identified PPI between 3Dpol and seven IFN pathway proteins, namely, IKKα, IKKε, IRF3, IRF7, NEMO, MDA5 and MAVS. These PPI are conserved among the four studied species, with the exception of the one between 3Dpol and MAVS, which was only found with the swine protein. We also showed, using luciferase reporter assays, that 3Dpol could inhibit the induction phase of the IFN pathway. These results demonstrate, for the first time, a putative role for 3Dpol in FMDV innate immune escape.
Research Advances on the Stability of mRNA Vaccines
Authors: Cheng Feiran , Wang Yiping , Bai Yu , Liang Zhenglun , Mao Qunying , Liu Dong , Wu Xing , Xu Miao
Published: March 2023

Compared to other vaccines, the inherent properties of messenger RNA (mRNA) vaccines and their interaction with lipid nanoparticles make them considerably unstable throughout their life cycles, impacting their effectiveness and global accessibility. It is imperative to improve mRNA vaccine stability and investigate the factors influencing stability. Since mRNA structure, excipients, lipid nanoparticle (LNP) delivery systems, and manufacturing processes are the primary factors affecting mRNA vaccine stability, optimizing mRNA structure and screening excipients can effectively improve mRNA vaccine stability. Moreover, improving manufacturing processes could also prepare thermally stable mRNA vaccines with safety and efficacy. Here, we review the regulatory guidance associated with mRNA vaccine stability, summarize key factors affecting mRNA vaccine stability, and propose a possible research path to improve mRNA vaccine stability.
Chikungunya Virus: Priority Pathogen or Passing Trend?
Authors: Montalvo Zurbia-Flores Gerardo , Reyes-Sandoval Arturo , Kim Young Chan
Published: March 2023

Chikungunya virus (CHIKV) is considered a priority pathogen and a major threat to global health. While CHIKV infections may be asymptomatic, symptomatic patients can develop chikungunya fever (CHIKF) characterized by severe arthralgia which often transitions into incapacitating arthritis that could last for years and lead to significant loss in health-related quality of life. Yet, Chikungunya fever (CHIKF) remains a neglected tropical disease due to its complex epidemiology and the misrepresentation of its incidence and disease burden worldwide. Transmitted to humans by infected Aedes mosquitoes, CHIKV has dramatically expanded its geographic distribution to over 100 countries, causing large-scale outbreaks around the world and putting more than half of the population of the world at risk of infection. More than 50 years have passed since the first CHIKV vaccine was reported to be in development. Despite this, there is no licensed vaccine or antiviral treatments against CHIKV to date. In this review, we highlight the clinical relevance of developing chikungunya vaccines by discussing the poor understanding of long-term disease burden in CHIKV endemic countries, the complexity of CHIKV epidemiological surveillance, and emphasising the impact of the global emergence of CHIKV infections. Additionally, our review focuses on the recent progress of chikungunya vaccines in development, providing insight into the most advanced vaccine candidates in the pipeline and the potential implications of their roll-out.
The Fourth Dose of mRNA COVID-19 Vaccine Following 12 Different Three-Dose Regimens: Safety and Immunogenicity to Omicron BA.4/BA.5
Authors: Kanokudom Sitthichai , Chansaenroj Jira , Suntronwong Nungruthai , Assawakosri Suvichada , Yorsaeng Ritthideach , Nilyanimit Pornjarim , Aeemjinda Ratchadawan , Khanarat Nongkanok , Vichaiwattana Preeyaporn , Klinfueng Sirapa , Thongmee Thanunrat , Srimuan Donchida , Thatsanathorn Thaksaporn , Sudhinaraset Natthinee , Wanlapakorn Nasamon , Honsawek Sittisak , Poovorawan Yong
Published: March 2023

The aim of this study is to investigate the reactogenicity and immunogenicity of the fourth dose using monovalent mRNA vaccines after different three-dose regimens and to compare the 30 µg BNT162b2 and 50 µg mRNA-1273 vaccines. This prospective cohort study was conducted between June and October 2022. The self-recorded reactogenicity was evaluated on the subsequent 7 days after a fourth dose. The binding and neutralizing activity of antibodies against the Omicron BA.4/5 variants were determined. Overall, 292 healthy adults were enrolled and received BNT162b2 or mRNA-1273. Reactogenicity was mild to moderate and well tolerated after a few days. Sixty-five individuals were excluded. Thus, 227 eligible individuals received a fourth booster dose of BNT162b2 (n = 109) and mRNA-1273 (n = 118). Most participants, regardless of the type of previous three-dose regimens, elicited a significantly high level of binding antibodies and neutralizing activity against Omicron BA.4/5 28 days after a fourth dose. The neutralizing activity against Omicron BA.4/5 between the BNT162b2 (82.8%) and mRNA-1273 (84.2%) groups was comparable with a median ratio of 1.02. This study found that the BNT162b2 and mRNA-1273 vaccines can be used as a fourth booster dose for individuals who were previously immunized with any prior three-dose mix-and-match COVID-19 vaccine regimens.
A Novel Vaccine Strategy to Prevent Cytauxzoonosis in Domestic Cats
Authors: Weerarathne Pabasara , Maker Rebekah , Huang Chaoqun , Taylor Brianne , Cowan Shannon R. , Hyatt Julia , Tamil Selvan Miruthula , Shatnawi Shoroq , Thomas Jennifer E. , Meinkoth James H. , Scimeca Ruth , Birkenheuer Adam , Liu Lin , Reichard Mason V. , Miller Craig A.
Published: March 2023

Cytauxzoonosis is caused by Cytauxzoon felis (C. felis), a tick-borne parasite that causes severe disease in domestic cats in the United States. Currently, there is no vaccine to prevent this fatal disease, as traditional vaccine development strategies have been limited by the inability to culture this parasite in vitro. Here, we used a replication-defective human adenoviral vector (AdHu5) to deliver C. felis-specific immunogenic antigens and induce a cell-mediated and humoral immune response in cats. Cats (n = 6 per group) received either the vaccine or placebo in two doses, 4 weeks apart, followed by experimental challenge with C. felis at 5 weeks post-second dose. While the vaccine induced significant cell-mediated and humoral immune responses in immunized cats, it did not ultimately prevent infection with C. felis. However, immunization significantly delayed the onset of clinical signs and reduced febrility during C. felis infection. This AdHu5 vaccine platform shows promising results as a vaccination strategy against cytauxzoonosis.
Streamflow Estimation in a Mediterranean Watershed Using Neural Network Models: A Detailed Description of the Implementation and Optimization
Authors: Oliveira Ana Ramos , Ramos Tiago Brito , Neves Ramiro
Published: March 2023

This study compares the performance of three different neural network models to estimate daily streamflow in a watershed under a natural flow regime. Based on existing and public tools, different types of NN models were developed, namely, multi-layer perceptron, long short-term memory, and convolutional neural network. Precipitation was either considered an input variable on its own or combined with air temperature as another input variable. Different periods of accumulation, average, and/or delay were considered. The models’ structures were optimized and automatically showed that CNN performed best, reaching, for example, a Nash–Sutcliffe efficiency of 0.86 and a root mean square error of 4.2 m3 s−1. This solution considers a 1D convolutional layer and a dense layer as the input and output layers, respectively. Between those layers, two 1D convolutional layers are considered. As input variables, the best performance was reached when the accumulated precipitation values were 1 to 5, and 10 days and delayed by 1 to 7 days.
Cyanobacterial Blooms Increase Functional Diversity of Metazooplankton in a Shallow Eutrophic Lake
Authors: Tian Xue , Yuan Yuxiang , Zou Yuanchun , Qin Lei , Zhu Xiaoyan , Zhu Yu , Zhao Yuxi , Jiang Mengyu , Jiang Ming
Published: March 2023

Harmful cyanobacterial blooms disrupt aquatic ecosystem processes and biological functions. However, studies focusing on the effect of cyanobacterial blooms on the functional diversity of consumers are still insufficient. To examine the interactions of cyanobacterial blooms and the diversity and composition of metazooplankton, we investigated the variation in metazooplankton and their driven variables during the cyanobacterial bloom and non-bloom periods in 2020 and 2021 in Lake Xingkai. We found that cyanobacterial blooms reduced the metazooplankton species diversity but increased their biomass, functional dispersion, and functional evenness. Generalized additive mixed model results revealed that cyanobacteria showed different effects on metazooplankton biodiversity and functional diversity during the bloom and non-bloom periods. Variance partitioning analysis indicated that cyanobacteria, physicochemical variables, and temporal variation explained 15.93% of the variation in metazooplankton during the bloom period and 20.27% during the non-bloom periods. Notably, cyanobacteria during the bloom period explained more variations in metazooplankton composition than those during the non-bloom period. Our results suggest that cyanobacterial blooms significantly impact the functional diversity and community composition of metazooplankton. Physicochemical and spatiotemporal factors may mask the effects of cyanobacteria on metazooplankton. Our findings may improve the understanding of the dynamics and responses of metazooplankton communities to environmental changes and cyanobacterial blooms disturbances and enhance our ability to assess the effectiveness of aquatic ecosystem restoration and eutrophication management.
Geometry of Local Scour Holes at Boulder-like Obstacles during Unsteady Flow Conditions and Varying Submergence
Authors: Schlömer Oliver , Herget Jürgen
Published: March 2023

Local scour holes are erosional bed structures that are related to different scientific disciplines in Earth science and hydraulic engineering. Local scouring at naturally placed boulders is ubiquitous, but many competing factors make it difficult to isolate the effects of a given variable. This is especially true for local scouring at natural instream obstacles that are exposed to unsteady flow conditions in the course of flood hydrograph experiments. Experimental investigations in laboratory flumes offer the advantage that boundary conditions can be systematically varied. We present novel experimental data on the impact of the submergence ratio, hydrograph skewness, and flow intensity on local scouring at boulder-like obstacles during unsteady flow and evaluate the effect of discharge chronologies. In total, 48 flume experiments on subcritical clear-water conditions and channel degradation were performed. The experimental results reveal that local scouring dominantly occurred at the rising limb when flow depth was comparable to the obstacle size, so the obstacle was unsubmerged. The steeper the rising limb, the quicker the local scour hole matured. The experimental results are relevant for the hydraulic interpretation of local scour holes found at boulders in the field. They may be utilized as a proxy for the minimum duration of the beginning stage of a flood.
Smooth Switching Method for Multi-Mode Synchronous Space Vector Modulation of NPC Three-Level Inverter
Authors: Zhang Guozheng , Zhao Guoao , Li Chen , Li Xinmin , Gu Xin
Published: March 2023

To meet the requirements of output harmonic distortion of neutral point clamped (NPC) three-level inverter under low switching frequency conditions, multi-mode synchronous space vector modulation is usually adopted. When switching between different pulse patterns, there will be oscillation in the output current. This paper proposes a smooth switching method for synchronous space vector modulation. This method compensates the phase angle of the reference voltage vector, in order to make the flux trajectories continuous before and after switching. Multi-position smooth switching can be realized in the fundamental period, and there is no delay in switching. Compared with direct switching, the total harmonic distortion rate of current during switching is reduced. The calculation of the phase angle compensation value of the reference voltage vector is not affected by the specific parameters and operating conditions of the motor, and can be carried out offline. Finally, experiments are carried out on a 7.5 kW induction motor fed by NPC three level inverter to verify the feasibility and effectiveness of the proposed method.
Penegakan Hukum dalam Pelayanan Pemungutan Pajak Kendaraan Bermotor (PKB) di Kantor Unit Pelaksana Teknis Pengelolaan Pendapatan Daerah (UPT PPD) Pandan, Provinsi Sumatera Utara
Authors: Tumanggor Posma , Zulyadi Rizkan , Siregar Taufik
Published: March 2023

The purpose of this study was to find out the legal arrangements, law enforcement obstacles and how to overcome them in collecting Motor Vehicle Tax (PKB) at the Pandan Regional Revenue Management Technical Implementation Unit Office (UPTPPD) based on the legal regulations in force in Pandan Region. The research method used in this research is Normative Juridical by searching and collecting data through library research from reading sources in the form of related legal books, opinions of legal experts, related laws and regulations, related websites and interview results. The results of the study show that the implementation of PKB collection at the Provsu BPPRD starts from registration, determination, payment by the taxpayer and validation to the deposit to the regional treasury by carrying out based on the Permen, Permendagri, Pergubsu that apply at UPT PPD Pandan as a form of implementation of Law no. 28 of 2009 concerning Regional Taxes and Levies. Furthermore, regarding obstacles in the implementation of motorized vehicle tax collection at the Regional Tax and Retribution Management Agency of North Sumatra Province, are the inclusion of the owner's identity (KTP and SIM) according to the tax note/STNK, technical gaps in service to taxpayers, PKB payments with the online system, payments via Banks, the large number of motor vehicle tax arrears objects both caused by the negligence of taxpayers in fulfilling their obligations to pay taxes.
Implementasi Peraturan Presiden Republik Indonesia Nomor 16 Tahun 2018 Tentang Pengadaan Barang Dan Jasa Pemerintah Pada Unit Pelaksana Teknis Jalan Dan Jembatan Kotanopan Dinas Bina Marga Dan Bina Konstruksi Provinsi Sumatera Utara
Authors: Matondang Andi Hakim , Hartono Budi , Harahap Dumasari
Published: March 2023

This study aims to find out and analyze the implementation and constraints in the Presidential Regulation of the Republic of Indonesia No. 16 of 2018 concerning Procurement of Government Goods and Services to the Kotanopan Road and Bridge Technical Implementation Unit of the Highways and Construction Services of North Sumatra Province. This research uses a descriptive method with a qualitative approach which is presented descriptively with a public administration juridical approach. The results showed that the Kotanopan Road and Bridge Technical Implementation Unit of the Highways and Construction Services of North Sumatra Province had not fully implemented the Procurement of Goods and Services (PBJ) according to Presidential Decree No. 16 of 2018. The obstacles faced are: there are individuals who seek personal gain from the implementation of road and bridge projects, the government's budget provision is often late, causing project implementation to falter, it is often difficult to identify the most urgent road and bridge needs due to weak information systems, as well as the lack of cooperation from external partner companies that try to cover up weaknesses in the results of project work at the time of handover.
Uso de AAS em pacientes cardiopatas e ocorrência de Úlcera Perfurada quais as melhores soluções? uma revisão sistemática com metánalise
Authors: Murta Marina Gabriela M. B. , Toqueton Tainá Rodrigues , Toqueton Tamires Rodrigues , Moraes Isabella Karoline Sousa , Marangoni Igor Parada , Mariano Pedro Henrique Mendonça , Brito Ogi Janderson Antunes de Castro , Moreira Camila Nascimento Portella de Barros , Drummond Júnior Délio Guerra , Duarte Aline Graziele Godoy , De Oliveira Elaine Ribeiro , Lima Mateus Além Silva , Mendes Filho Edivaldo Bezerra , Rossetto Isadora Silveira , Silva Ana Cláudia , Santos Sara Bastos , De Araujo João Victor Lima , Dias Lucas Furtado , Bernardes Gabriel Marquez , Magalhães Camilla Lafetá , De Deus Gabriely Gomides Couto , Leão Laríssa Assis Lima , Da Fonseca Maria Tereza Pasquini França , Soares Ariadne Barbosa , Buso Pedro Henrique , Carioca Marcus D Lucca , Araújo Letícia Faria , Sperandio Natalia Bertagnolli
Published: March 2023

A administração do ácido acetilsalicílico (AAS) é uma das medidas indicadaspelos médicos em caso de suspeita de infarto agudo do miocárdio. De acordo com os especialistas, o medicamento serve para diminuir a agregação de plaquetas e inibir a formação de coágulos no interior das artérias. O objetivo deste estudo é verificar na literatura o uso do Ácido Acetilsalicílico (AAS) em pessoas cardiopatas e sua possível relação com o aparecimento de úlcera. Trata-se de uma revisão sistemática com base em publicações, dos último cinco anos, que essa temática, extraídas de bases de dados eletrônicas como Scielo, PubMed, Lilacs, BVS, Embase e Medline, em língua inglesa e portuguesa. Dos estudo que se aproximaram do objetivo da pesquisa, muitos não relataram a estreita relação entre o uso AAS e o surgimento de úlcera. Assim, espera-se que este estudo sirva de incentivo para que mais estudos sejam realizados sobre essa temática afim de estabelecer e conhecer se há alguma relação entre o fármaco e a doença.
Surjektifitas Pemetaan Eksponensial untuk Grup Lie Heisenberg yang Diperumum
Authors: Kurniadi Edi , Maharani Putri Giza , Kartiwa Alit
Published: March 2023

The Heisenberg Lie Group is the most frequently used model for studying the representation theory of Lie groups. This Lie group is modular-noncompact and its Lie algebra is nilpotent. The elements of Heisenberg Lie group and algebra  can be expressed in the form of matrices of size 3×3. Another specialty is also inherited by its three-dimensional Lie algebra and is called the Lie Heisenberg algebra. The Heisenberg Lie Group whose Lie Algebra is extended to the dimension 2n+1 is called the generalized Heisenberg Lie group and it is denoted by H whose Lie algebra is h_n. In this study, the surjectiveness of exponential mapping for H was studied with respect to h_n=⟨x ̅,y ̅,z ̅⟩  whose Lie bracket is given by  [X_i,Y_i ]=Z.  The purpose of this research is to prove the characterization of the Lie subgroup with respect to h_n. In this study, the results were obtained that if ⟨x ̅,y ̅ ⟩=:V⊆h_n a subspace and a set  {e^(x_i ) e^(x_j )  ┤| x_i,x_j∈V }=:L⊆H then L=H and consequently Lie(L)≠V.
Synthetic Minority Oversampling Technique Pada Model Logit dan Probit Status Pengangguran Terdidik
Authors: Fatimah Fatimah , Fitrianto Anwar , Indahwati Indahwati , Erfiani Erfiani , Khikmah Khusnia Nurul
Published: March 2023

Educated unemployment is caused by a misalignment of educational development planning and employment development, resulting in underemployed graduates from various educational institutions. Unemployment data in DKI Jakarta shows an unequal class. Unbalanced data is a severe problem of modeling because it can cause prediction errors that affect the accuracy of the resulting model. Using SMOTE to handle unbalanced data will likely increase the model’s accuracy. This study aims to find the best model for identifying the factors influencing the status of educated unemployment using logit and probit models and handling unbalanced data using SMOTE. The results showed that the independent variables that affect the status of educated unemployment in the logit and probit models are the same: age group and participation in training. The independent variables that affect the status of educated unemployment in the logit and probit models with SMOTE are also the same: age group, marital status, and participation in training. Unbalanced data handling using SMOTE can increase the balanced accuracy value significantly. Balanced accuracy values for the logit and probit models with SMOTE are higher than the logit and probit models without SMOTE. The logit model with SMOTE is the best because it has the highest balanced accuracy value compared to other models. According to the logit model with SMOTE, the educated unemployed in DKI Jakarta are young and have never married. There is a need for the government to play a role in improving the quality of educational institutions in producing graduates who meet company qualifications and can be hired by employers. Unemployed people who have attended the training, despite having a higher education, may also become unemployed. The training provided has not been able to reduce the unemployment rate. As a result, the government should be able to provide training to improve entrepreneurship skills while also providing capital in the form of business loans to reduce educated unemployment.
METHODOLOGY FOR IMPROVING THE EFFECTIVENESS OF THE FACE IDENTIFICATION ALGORITHM
Authors: Вивчарь Р.М. , Пачин А.В. , Титаренко И.О. , Киричек Р.В.
Published: March 2023

Рассмотрена методика повышения эффективности алгоритмов идентификации лиц в различных биометрических системах. Представлены основные показатели эффективности алгоритмов идентификации лиц (точность идентификации, ее полнота и продолжительность, а также затраты вычислительных ресурсов), приведен порядок их оценивания. Представлены рекомендации по повышению показателей эффективности алгоритмов идентификации в случае получения их неудовлетво­рительных оценок. Ключевые слова: идентификация лиц, эффективность, биометрические системы

The article discusses a technique designed to improve the effectiveness of algorithms for face identification in various biometric systems. The main indicators of the effectiveness of face identification algorithms (accuracy of identification; completeness of identification; duration of identification; costs of computing resources) are presented, the order of their evaluation is given. Recommendations for improving the efficiency of identification algorithms in case of obtaining unsatisfactory ratings are presented.
CURRENT PROBLEMS OF LICENSING INTERNET SERVICES THAT MAKE VOICE CALLS TO THE PSTN NETWORK
Authors: Пальцин Д.А. , Фень А.С. , Гусев В.М. , Деарт И.Д.
Published: March 2023

Совершенствование пакетных технологий коммутации создало возможность передачи голосовой информации по сетям передачи данных, что оправданно с точки зрения эффективного использования дорогостоящей телекоммуникационной инфраструктуры. При этом практика применения новых технологий зачастую опережает нормативное регулирование, что создает неопределенности как в отношениях между операторами связи, так и в объемах и качестве услуг, предоставляемых абонентам. В настоящей работе проводится анализ действующих нормативных требований и сложившейся практики предо­ставления услуг интернет-сервисов. Особое внимание уделено возникшим практическим вопросам реализации, зачастую не определенным в нормативных требованиях или допускающим возможность их противоречивого толкования.

The improvement of packet switching technologies has made it possible to transmit voice information over data transmission networks, which is justified in terms of efficient use of expensive telecommunications infrastructure. At the same time, the practice of using new technologies often outstrips regulatory regulation, which creates uncertainty both in the relationship between telecom operators and in the volume and quality of services provided to subscribers. This paper analyzes the current regulatory requirements and the current practice of providing Internet services. Special attention is paid to the practical implementation issues that have arisen, which are often not defined in the regulatory requirements or allow for the possibility of their contradictory interpretation.
RESEARCH ON WATER QUALITY IN THE DNIESTER RIVER 2019-2021
Authors: Marusic Galina , Sava Nina , Braniste Rodica
Published: March 2023

The article examines the water quality of the Dniester River for the period 2019-2021. Are analyzed the data concerning the degree of pollution of the Dniester River and its tributaries. Is discussed the negative impact of the detected pollutants on human health. The results of the statistical analysis using R language tools are presented. Is proposed the statistical model for approximation of the analyzed data.
Magnetic-laser therapy in multidisciplinary rehabilitation of patients with chronic non-specific dorsalgia with high intensity pain syndrome in outpatient care
Authors: Vasilyeva-Linetska L.Ya. , Manoilenko N.Yu.
Published: March 2023

The effectiveness of the analgesic impact of magnetic-laser therapy (MLT) and its combinations with other methods with have a aproved analgesic effect used for multidisciplinary rehabilitation of patients with chronic nonspecific dorsalgia (CNSD) with marked pain syndrome in a polyclinic has been studied. 107 patients with high intensity pain syndrome (on a VAS scale from 6 to 8 points is severe pain) in CNSD exacerbation phase were included. The patients were divided into five homogeneous groups. All patients were treated with kinesiotherapy (KT). In addition, patients of the 1st group were treated with MLT; patients of the 2nd group were treated with sinusoidal modulated currents (SMT); patients of the 3rd group were treated with ultraphonophoresis with non-steroidal anti-inflammatory drugs (UPP NSAID); patients of the 4th group were treated with complex of MLT and SMT; patients of the 5th group were treated with MLT and UPP NSAID. Pain dynamics was assessed using VAS, while patient functional capabilities - using FAS-9 questionnaire. MLT application in 1st group patients decreased pain and altered functions very slightly (p>0.05). Ten sessions of SMT or UPP together with KT caused transition of severe pain to moderate - from (5.67±0.37) to (3.30±0.26) and from (5.75±0.34) to (3.72±0.31) points, respectively (p<0.001), which allowed to increase significantly the activity of KT. MLT and SMT combination after 8 sessions has caused two-fold pain decrease – from (5.96±0.39) to (2.82±0.25) points (p<0.001) and significantly improved movement biomechanics. SMT or UPP combination with MLT potentiates antinociceptive effect of both modalities, so patient functional capabilities regenerate earlier. This fact allows to apply KT from the first day of rehabilitation, which leads to the reduction of rehabilitation time.

Keywords: chronic non-specific dorsalgia, multidisciplinary rehabilitation, kinesiotherapy, magnetic- laser therapy, sinusoidal modulated currents, NSAID ultraphonophoresis.
Features of drug pharmacotherapy in patients with heart failure after pacemaker implantation
Authors: Voronenko O.S.
Published: March 2023

Over the past decades, an increase in mortality from chronic heart failure (CHF) has been recorded, for the treatment of which the implantation of an electrocardiostimulator can be used. The medical support of the patient with a pacemaker was optimized depending on the functional class (FC) of CHF. An increase in both the frequency of prescription and the dose of (3-adrenergic receptor blockers with an increase in the FC of CHF in patients with CHF at a one-year follow-up period after implantation of pacemakers was shown. This not only improves myocardial contractility, but also reduces the risk of complications of pacing. Patients with implanted pacemakers require careful titration of medications taking into account the FC of CHF, especially with regard to its high FC, primarily for therapy with angiotensin-converting enzyme inhibitors, antiplatelet agents, and antiarrhythmic drugs.

Keywords: chronic heart failure, pacemaker implantation, drug therapy.
Otxandioko hizkera: adinaren araberako bariazioa
Authors: Ormaetxea José Luis
Published: March 2023

Lan honekin aztertu nahi da zer bariazio dagoen euskalkia erabiltzen dutenen artean. Alegia, adina aldaera soziolinguistikoa kontuan hartuta, zeintzuk diren helduen eta gazteen artean dauden hizkuntza-desberdintasunak. Azterketa herri bakarrean egin da, Bizkaiko Otxandion, eta hizkuntzaren hainbat alor bereiziz: lexikoa, izen-morfologia, aditz-morfologia eta sintaxia. Arreta berezia jarri zaio euskara batuaren eraginari.
Los efectos educativos a largo plazo de una expansión a gran escala de la oferta de educación preescolar: evidencia para Argentina
Authors:   , González Fabián Enrique
Published: March 2023

La educación preescolar universal experimentó un incremento importante en las décadas de 1980 y 1990, tanto en países desarrollados como en desarrollo. Sin embargo, los estudios que analizan los efectos de estas políticas son escasos, centrados en su mayoría en resultados de corto plazo y en países desarrollados. Este trabajo analiza el impacto de una expansión a gran escala de la oferta de educación preescolar en Argentina en resultados educativos de los niños beneficiados, llevada adelante en el periodo 1993-1999. Explotando la introducción progresiva del programa, la cual es una fuente de variabilidad exógena entre provincias y en el tiempo, se encuentra que el programa incrementó la matriculación en el nivel secundario y los años de educación alcanzados por los beneficiados. Teniendo en cuenta que el programa habría contribuido a desarrollar habilidades cognitivas y no cognitivas en la infancia temprana, según evidencia previa de Berlinski et al. (2009), se concluye que este es el principal mecanismo, descartando otros potenciales canales.
Contribución al estudio químico de los insecticidas del comercio a base de piretro
Authors:   , Margulis Moisés
Published: March 2023

La República Argentina consume anualmente de 4 á 5 millones de litros de diversas soluciones insecticidas, las que se han incorporado como elementos defensivos en los últimos años en casas, habitaciones, establecimientos comerciales, industrias, etc., para destruir los insectos y parásitos que pululan en los meses de Diciembre a Marzo inclusive. Estas soluciones insecticidas son utilizadas en la vida doméstica sin un control analítico adecuado, que asegure su innocuidad y establezca como es lógico el tenor en principios activos. Ante esa evidencia tantas veces comprobada, nos hemos propuesto abordar el problema, con la esperanza de poder traer algún beneficio a la salud pública, librada hasta hace poco tiempo, salvo algunas excepciones, a la voluntad más o menos honorable de sus preparadores industriales. * Entre los técnicos del país se ha vulgarizado la creencia de que no es posible establecer, en los insecticidas a base de piretro, por vía química, la cantidad de piretrinas existentes en los líquidos o sus extractos concentrados. Últimamente (febrero de 1935) apareció una reglamentación en la provincia de Buenos Aires donde se exige una valoración química para los polvos insecticidas, dejando al solo arbitrio de la prueba fisiológica las numerosas soluciones insecticidas y líquidos mosquicidas, que se expenden en el comercio, cuyos agentes comerciales declaran, sin excepción, que todos son preparados a base de piretro. Numerosos investigadores, en diversas partes del mundo, han discutido respecto de la necesidad de realizar el control químico de esos preparados; por nuestra parte, hemos querido reunir todo ese material experimental disperso para ponerlos al servicio de los laboratoristas, porque la higiene pública reclama la comprobación de la eficiencia de los insecticidas para quienes van dirigidos y su absoluta innocuidad para los seres y elementos que los rodean.
The history of the revolutionary Northern Euroasia: anthropology of science life and global cooperation (1957—2019)
Authors: Исхаков С.М.
Published: March 2023

Статья посвящена Совету по истории революций, реформ, социальных движений в Северной Евразии, возникшему в Академии наук СССР в середине ХХ века и ликвидированному в 2019 г. Рассматривается международное сотрудничество советских и российских исследователей, сотрудничавших с этим Советом, показано значение этого сотрудничества для появления новых идей, стимулирования новаторского поиска, расширения документальной основы изучения истории Северной Евразии в ХХ веке, характеризуется роль историков, которые внесли тот или иной вклад в международную научную жизнь, дается представление о том, как складывалось взаимодействие историков разных стран с представителями Российской академии наук. В статье особое внимание уделено малоизвестным эпизодам академической антропологии и повседневности.

The article is dedicated to the Council of the History of Social Movements, Reforms and Revolutions in Northern Euroasia. It was established in the middle of the 20th century at the Russian Academy of Science and existed till 2019. Shown is the importance of international connections of Russian and Soviet scientists, who took part in the Council. Those connections brought new ideas, stimulated new approaches, new sources were available for further research on the History of Northern Euroaisa in the 20th century. Special attention is paid to lesser-known episodes of academic everyday life and anthropology.
Decision Making Support System for the Diagnostics of the Cardiovascular System Pathologies by the X-ray Images of the Chest
Authors: Radzhabov A. G.
Published: March 2023

The lack of universal (generalized) data sets, as well as the lack of annotated data, creates the need to study the possibilities of neural network approaches for specific data sets. The importance of building algorithms for detecting extrapulmonary pathologies on chest X-ray images is dictated by the great social significance of many diseases of this group (for example, cardiovascular diseases), given the availability of such images, due to the widespread use of minimally invasive and relatively cheap X-ray diagnostic methods. One of the most impor tant issues in solving the problems of automating the classification of medical images is data preparation. As a result of work on the image base, the performance of the final algorithm has been increased from 75 to 95 %. The processing of the entire volume of the obtained images and their diagnostics for a wide list of pathologies are difficult for medical institutions because of the limited resources. In this regard, it is advisable to use the automation of segmentation and recognition processes, which even at the first stages of development of the technology makes it possible to redistribute the attention of doctors, focusing on potentially pathological cases and returning attention to cases mistakenly identified as non-pathological.