bluuebunny/crossref_metadata_2025 huggingface dataset:
Reimagining the Populism and Leadership of Miss Fatima Jinnah
Authors: Zaheer Sana , Chawla Muhammad Iqbal
Published: July 2020

This article explores dynamics of Miss Fatima Jinnah’s leadership qualities by applying the Ideational approach. The article aims to re-think the scenario of Pakistan at the eve of presidential elections 1965 with regarding populism. It underscores causes, events and consequences of the 1965’s Elections by re-contextualizing the views and actions of Miss Jinnah. She won the elections, but a large-scale rigging deprived her of becoming the first lady President of Pakistan and in Islamic World. She did not play an active part in the political arena until the Presidential elections challenging the military dictator. This study attempts to answer why the Mother of the land opted for the politics of resistance; how she took an active part in the election campaign, and what were the implications of her participation in the elections by situating her role in national politics through the theoretical lens of populism.
The Impact of Abusive Constitutionalism on Democracy in Pakistan
Authors: Amin Husnul , Qurban Shafiq , Siddiqa Maryam
Published: July 2020

This research concerns the constitutional development in Pakistan with a specific reference to 21st Amendment to the Constitution of Pakistan. It is widely perceived among scholarly and semi-scholarly circles that the tendency of militarys direct intervention in politics; toppling democratically elected government has been declined for the last many decades across the world. According to the new trends, military interferes in the state affairs through indirect means. One of the indirect means includes abusive constitutionalism that involves constitutional amendment and constitutional replacement as mechanisms for constitutional change. The paper explores whether 21st Amendment to Constitution of Pakistan was an abusive constitutionalism that really empowered military to get a strong hold on key policy making areas of national interest during the democratic rule. The research concludes that the 21st Amendment was an abusive constitutionalism as it curtailed civil liberties and fundamental rights of the citizens and hence undermined democracy in Pakistan.
Social Media, Democracy and Fake News in Pakistan: An Analysis
Authors: Haseeb Ur Rehman  , Hussain Shabir , Durreshehwar
Published: July 2020

In this study, the researchers examined the prevalence of fake news in the social media debates on Pakistani politics and society. The content analysis showed that both Twitter and Facebook carried a sizeable number of fake news relating to the politics and international affairs, military, economy and religion. Though more fake news was posted relating to politics and politicians, fake news stories relating to international relations got more likes and share as compared to other topics. Interestingly, even though the fake news was busted as fake and not genuine, these continued getting attention of people. This indicates the influence of cult following and populism on the Pakistani social media users. The findings of this study support the available scholarship on the prevalence of fake news, its popularity and spread in the Western world.
The Position of Afghan Refugees under Various Agreements and Constitution of Pakistan: An Analysis
Authors: Zubair Muhammad , Shahzad Suhail , Aqeel Khan Muhammad
Published: July 2020

This article explores the legal position of Afghan refugees in Pakistan (as it has no refugee related legislation at national level nor a signatory to refugee related instruments at international level) in the light of . various agreements which it has concluded with the UNHCR and the Afghan government along with the various protections available under the 1973 Constitution. A total of eight agreements which started with the first one in 1988 have been concluded among the Government of Pakistan (GOP), the United Nations High Commissioner for Refugees (UNHCR) and the Government of Afghanistan (GOA) under which various rights have been extended to them apart from their refugee status recognition. The Constitution of Pakistan also affords them certain fundamental rights irrespective of their status as they are currently living in Pakistan’s territorial jurisdiction, which enables them to claim those rights. Their life and liberty is as protected as any other citizen of Pakistan.
Determination of Education and Training, Discipline, Leadership Style on Loyalty Through work Satisfaction of Pamong Praja Police Units Uniters in Bintan Regency
Authors: Harianti Venny , Wibisono Chablullah , Indrayani
Published: July 2020

The human resources strongly influence the success of an organization in achieving its goals at the management level (elements of the leader/officials), at the staff/employee level; it is one of the determining factors in the success of an organization. Proper discipline will have an impact on high loyalty. It is highly desirable to conduct research for finding relation between human resources and achievement of an organization. Researchers used data processing using SEM with AMOS version 24 software; the sample of respondents numbered 138. The value of square multiple correlation training, discipline, leadership style, and job satisfaction showed 2.90%. Thus, it can be stated that changes in loyalty are determined by the contribution of training,discipline, leadership style, and job satisfaction; by 2.90%, the remaining 7.10% is the contribution of other variables that have not been included in this study. Changes in loyalty are determined by the contribution of training, discipline.
IMPLEMENTATION OF ECONOMIC ORDER QUANTITY (EOQ) ON INVENTORY EFFICIENCY IN PT. HEALTH TODAY INDONESIA
Authors: Adawiyah Al , Umam Khoirul
Published: July 2020

Optimal inventory management is one of the main problems that is often encountered in the company's production activities which leads to the company's overall efficiency and profitability. PT. Health Today Indonesia is one of the companies experiencing this problem. Thus, this descriptive research with a quantitative approach aims to find solutions to these problems. Secondary data analysis from the 2013-2016 report uses the Economic Order Quantity (EOQ) calculation model from several divisions that are relevant to the 5 main products namely Fruit Smoothies, Bubble, Trisco, Honey and Sunfield. The results showed that the company was able to increase production efficiency, but this was not an actual condition due to externalities and the company's internal policy to delay the addition of purchases of raw materials and inventory, making the trend of inefficiency of the company's production decreased.

Keyword:Economic Order Quantity, Inventory Management, Production
Pengaruh Persepsi Kualitas, Citra Merek, Brand WarenessPadaKeputusan Pembelian Pada CV Pia Manalagi KetapanKota Probolinggo
Authors: Hidayatullah Elmas MuhammadSyarif
Published: July 2020

Based on research to know the effectof perception the quality, brand image, brand awareness trhadap decision the purchase by consumers CV.Pia Manalagi Ketapang ProbolinggoCity.Population research every consumer CV.Pia Manalagi Ketapang ProbolinggoCity.Sample consist of 30 respondents to technique incidental sampling.The method of analysis data using the validity, reliability test, regression analysis linear multiple and analysisthe coefficients determination.Based on the results of the testing of hypotheses done can be concluded that variable perception the quality, image brands and brand awareness based partial having influence a positive and significant on the decision the purchase CV.Pia Manalagi Ketapang ProbolinggoCity.The coefficients analysis determination show 69,7 % decision buy effectby perception the quality, brand image, brand awareness.

Keywords: Perception of quality, brand image, brand awareness, purchasing decision
Experience of Intra-University Cooperation in the Process of Creating Professionally-Oriented Foreign Language Textbooks
Authors: Popova N. V. , Almazova N. I. , Evtushenko T. G. , Zinovieva O. V.
Published: July 2020

The article discusses the creation of professionally-oriented foreign language textbooks in the process of interaction between the department of foreign languages and the specialized departments of a technical university. Inter-departmental cooperation is considered as a university resource for improving the quality of higher education; examples of successful interdepartmental cooperation at the Peter the Great St. Petersburg Polytechnic University are given. It is shown that a characteristic feature of a professionally-oriented textbook of the new generation, created by the joint efforts of the linguistic and specialized departments is the widespread use of the elements of the computer-based learning environment, which contributes to a more effective mastering of the subject content. A list of seven English language textbooks created as a result of inter-departmental cooperation, and a brief analysis of the problems that arose in the process of communication between specialists of linguistic and technical profiles are presented. It is shown that the process of creating foreign language textbooks can be simultaneously used as a practice-oriented interdisciplinary project for master degree students of a linguistic profile who participate in it as developers of the linguistic content of these textbooks. Participation of the postgraduates in this project is supported by the curricular discipline “Interdisciplinary links in higher education” and teaching practice.
Customization of a University Graduate: Illusion or Requirement of Time?
Authors: Leushin I. O. , Leushina I. V.
Published: July 2020

The article focuses on the problems of the implementation of the educational process in the University, taking into account the interests and needs of employers in the context of the transition of Russian higher education to the updated educational standards designed to take into account the requirements of applicable professional standards. The reasons of emergence of a situation, when a young specialist, sharply focused on the needs of a particular employer is unable to solve professional problems in conditions of other industrial sites and laboratories. The authors demonstrate the negative effects of the so-called «in-depth professionalization» and isolation of graduates from the competition held by the University in the interests of the particular employer. The article dwells on the preventive measures to eliminate these phenomena in the framework of «university – employer » cooperation, taking into account the individual interests of the student who is originally a full stakeholder of educational process. The term «customization» derived from marketing means fine tuning of graduates according to the specific requirements of a particular employer. The article provides a critical analysis of customization with regard to the Russian higher education in the historical aspect. The authors substantiate the need of complex customization of graduates, which implies that all University partners and stakeholders should be involved in educational process. Such complex customization may engage regional resource centers, centers of competence, centers of excellence and centers of engineering which are free from corporate interests.
Evaluation of the Engineering Curriculum Elements for Compliance
Authors: Chuchalin A. I.
Published: July 2020

Rubrics have been developed to evaluate the level of compliance of curriculum elements with the recommendations of the CDIO-FCDI-FFCD Standards in the process of modernizing engineering programs for undergraduate, graduate and postgraduate studies. As an example, the author presents the results of the evaluation of engineering undergraduate program courses for compliance with the recommendations of the CDIO Standards in the form of total and differentiated ratings of the modules of the humanities and social sciences, natural sciences and mathematics, basic engineering and specialized professional courses. Based on the ratings, the initial (before modernization) and planned (after modernization) levels of compliance of the program modules with the recommendations of each of the 12 CDIO Standards are determined. Using the rubrics enables to involve all the instructors in the process of engineering program modernization.
Application of the Monti procedure in Adult Continent Cutaneous Urinary Diversion.
Authors: GALIQI Gëzim , BAJRI Luan , PESHA Albert , KONI Artan , SHEGA Bledar
Published: July 2020

Introduction; Monti and co. described in 1997 is a continent catheterizable conduit using short segments of the ileum (1). The use of this technique allows us to obtain 2 to 2.5 cm segment of the ileum to achieve a tabularized segment of 7-8 cm. The 15 cm of terminal ileum was not routinely used for this type of procedure. After the reconstruction of a tunnel, anastomosis was performed on the superior part of the posterio-lateral junction of the bladder.

Objectives: To report 6 cases using the Monti procedure with ileum for adult continent cutaneous urinary diversion, from different etiologies.

Materials and Methods: From 2007 to 2020 we treated 6 patients with different conditions with this procedure. First case was a middle-aged woman with a big vesico-vaginal fistula (fig.3) It was unappropriated to be closed with satisfactory functional results in terms of continence, because a part of the sphincter was destroyed also. The reason of damage was auto mutilation as a result of borderline personality.

Discussion: Monti procedure associating Mitrofanoff principle was mainly used in pediatric patients (1,2,3) That’s because of the relatively easy execution of the “Mitrofanoff principle” and the high degree of continence obtained with its use (4). But can we use the same principle to resolve some difficult cases in adult urology also?

Conclusion: The Monti tunnel is a valid option for continent intermittent catheterisation. It’s also an alternative to be adjunct with Mitrofanoff procedure when needed. We used it when the appendix was not appropriate to be used as a tunnel or when it was missing. It has a good continent percentage and it can be done rather easily. Of course, ours is a small series of cases to represent more important conclusions.
Reference System from Health Levels to Emergency Clinic Center in Kosovo
Authors: LENJANI Basri , BAFTIU Nehat , RASHITI Premtim , BUNJAKU Ilaz , ARSLLANI Nuhi , KRASNIQI Blerim , MAKOLLI Shpresa , LENAJNI Dardan , LJUHAR Kenan , ZALIHIĆ Adem , GAVRANOVIĆ Aida , DEMI Arban
Published: July 2020

The process of patient referral system at the level of health care is a comprehensive institutional framework with responsible, well-defined competencies, as a network of cooperation with the general goal of maintaining health, treatment, stabilization, transport and medical care up to in the complete recovery of the sick. The process of patient referral system in most countries in Europe and in the world is a challenge for most developing and developed countries. The mechanisms of the referral system function at different national, regional and municipal levels based on national laws and policies and work on the basis of efficient lines of communication by creating clear and simple steps and procedures described. The referral system in Kosovo is disorganized, chaotic, the Ministry of Health must have a national document of the referral system for patients at the health level, and before that all health care professionals are educated, trained on the way of the referral system, which cases must be sent from the primary, secondary and tertiary level. At the national level, the National Coordinating Council with a national plan of the patient referral system can convey the quality; help the health care professionals based on the current health legislation, the harmonization of unique standardized protocols with follow-up guidelines. Patients at the country level.
Vowel transitions in the Northern dialect of North accent of the Azerbaijani language and “kipchak” language elements in them
Authors:   State Pedagogical University, Samedova Konul
Published: July 2020

The influence of Oghuz and Kipchak languages should be especially noted when talking about related languages. Because these languages are at the heart of the phonetics, vocabulary and grammar of the Azerbaijani dialects. Studying the history of a language and the role of intra-linguistic and extraneous influences is valuable and important enough to reveal the history of not only one language, but also of related languages close to that language. The Northern dialect of North accent of the Azerbaijani language which are vast in terms of territory, differ in the richness and diversity from other accents of the Azerbaijani language. Although there are many dialect features in this region, the dialects of the northern group combine the richness of both Oghuz and Kipchak language elements. The article identifies traces of Kipchak language features in dialectological materials collected from northern dialects, and thus the formation of Kipchak tribes in these regions is proved by linguistic facts.The article talks about the dialectological tasks of the interchangeability of sounds in the dialect (pronunciation) of the Azerbaijani language and vowel sound transitions in the dialect of the groups of the Northern dialect. This phonetic process, in contrast to the literary language, is more common in the adverb (manner of speaking, pronunciation). The study of these phonetic processes is of great importance for dialectical study (concept), as well as for the simultaneous study of the phonetics of languages, the level of their mutual integration into each other in Turkological linguistics (philology, linguistics). The article also clarifies the similarities and parallelism of the transition of vowels of the Northern dialect of the Azerbaijani language with elements of the “kipchak” language. The process of transition of the Northern dialect and their interchangeability is investigated, analyzed, studied using (based on) the table of M.Shiraliev’s groupings
锻炼才是提高免疫力的良方？
Authors: 康 宇
Published: July 2020

身体的免疫力降低原因有很多,其中一个是大多数幼儿存在的,就是平日里不喜欢锻炼,过惯了舒适的生活使得自己没法“迈开腿”,经常不爱运动的幼儿,免疫力也会相对下降,当幼儿身体的“保护”功能开始下降的时候,一些细菌、病毒就会“趁虚而入”,幼儿就很容易出现体弱多病的情况,也会变成易病体质。当幼儿的生活中缺乏锻炼时,他的身体体质就会变得非常差,免疫力也会非常的差。机体的免疫力好,体内对病原的反应快、消除的也快。锻炼身体能增强免疫力,不过要坚持经常锻炼才有效。但是,过量运动后抵抗力反而从增强往下走,因此运动一定要适量。
论教育孩子的方法
Authors: 胡 元
Published: July 2020

家庭教育,是教育的组成部分之一,是终身教育,它开始于孩子出生之日,婴幼儿时期的家庭教育是“人之初”的教育,在人的一生中起着奠基的作用。孩子上了小学、中学后,家庭教育既是学校教育的基础,又是学校教育的补充和延伸。著名心理专家郝滨老师曾说过：“家庭教育是人生整个教育的基础和起点”。家庭教育是对人的一生影响最深的一种教育,它直接或者间接地影响着一个人人生目标的实现。
现代信息技术在幼儿园语言教学中的运用研究
Authors: 金 艳萍
Published: July 2020

随着我国信息技术的发展,其在各行各业中的重要性日益凸显。在幼儿语言教学过程中,运用现代信息技术有助于为幼儿创造良好的教学氛围和教学环境,有助于创新教学形式激发幼儿的学习兴趣,提升幼儿的语言表达和应用能力。基于此,本文主要探讨现代信息技术在幼儿园语言教学过程中的运用。
浅析湖南省山地型风电场建设对鸟类迁徙的影响及对策建议
Authors: 殷 芙蓉 , 黄 河仙 , 李 翔 , 颜 剑波
Published: July 2020

本文以湖南省山地型风电规划及场址分布特征与境内鸟类迁徙通道的位置关系为切入点,从鸟类迁徙习性和风电场运行特征两个方面分析湖南省山地型风电场建设对鸟类迁徙的影响,探讨风电机与鸟类相撞的影响因素,提出鸟类保护措施,为环境保护部门和从事风电场开发与管理的研究和工作人员提供参考。
浅谈乡镇林业站如何保护森林资源
Authors: 李 自元
Published: July 2020

森林资源是人类赖以生存和发展的重要资源,保护生态环境具有非常重要的意义,是一项惠及子孙、意义无限的伟大事业,是林业生产的希望工程。乡镇林业站是森林保护的主要执行者,是林业主管部门联系广大林农的纽带和桥梁,是各项林业工作的真正落脚点。为此,我将要在本文中对乡镇林业站如何保护森林资源进行探讨,希望对促进我国林业事业的发展,可以起到有利的作用。
生物滤池处理废气技术在城市污水处理厂废气净化中的应用
Authors: 郑 达
Published: July 2020

城市污水处理厂在工业生产过程中会产生很多废气,不仅对自然环境产生不利影响,还会对周围居民的生活产生影响。所以,城市污水处理厂需要严格控制废气排放质量,采用先进的技术对废气进行净化。本文主要研究生物滤池处理废气技术在污水处理厂废气净化中的应用,分析生物净化技术的应用,对废气净化的效果进行研究,希望对城市污水处理厂废气净化工作具有积极作用。
浅析城市污水处理对环境保护工程的重要性
Authors: 郑 淑琴
Published: July 2020

近年来,随着城市化的快速发展,城市污水处理也成为了一项非常庞大又不可避免的市政问题,同时城市污水处理能力的高低也体现了整个城市的发展水平。城市污水一旦处理不好,不仅影响市容市貌,也会给环境保护带来巨大的负担和压力,且长期持续容易影响城市的长久发展。基于此,本文首先讲述了城市污水处理对环境保护工程的重要性,然后对我国城市污水处理的现状进行了研究,并且提出了城市污水处理的措施,以此希望能给城市污水处理带来更好的发展。
环境监测在大气污染治理中的作用及措施
Authors: 张 宏伟
Published: July 2020

大气污染是我国环境问题中较为突出的环境污染问题,环境监测是一种结合物理、化学等多领域的综合监测手段,也是大气污染治理的数据基础和行动依据。因此为了保障大气污染治理的有效性,本文概述了环境监测与大气污染,对环境监测在大气污染治理中的作用及其措施进行了探讨分析。
中山市民众镇生态环境保护问题与对策
Authors: 唐 明云
Published: July 2020

这些年,随着中国城市化的发展,农村的生产和生活环境有了很大提升和改善。相关城镇化建设工作也取得了突破性的进展,全面有效地带动了社会经济发展及我国现代化建设。然而,在加速城市化进程中,我国农村生态环境面临着巨大的挑战。因此,需要在此基础上,分析相关环境发展中面临的不可避免的问题,提出相关发展措施及建议,以促进中国城市化的良性发展。基于此,本文以中山市民众镇为例,首先分析了中山市民众镇城镇化建设对生态环境的影响,其次分析了中山市民众镇生态环境保护存在的问题,并提出相应的对策。
固相微萃取法在环境监测中的应用
Authors: 徐 艳萍
Published: July 2020

目前,工业污染问题日益严重,在短期内很难得到有效缓解,且各种生活垃圾也会对生态环境造成一定的污染,尤其是有机物污染问题。为了有效地解决这些问题,相关部门必须引进固相微萃取法,将其应用到环境监测过程中,文章主要针对固相微萃取法在环境监测中的应用进行了分析。
环境管理体系分析填埋和焚烧无害化处置固体废弃物
Authors: 杜 娜
Published: July 2020

防治固体废弃物的环境污染是促进环境和循环经济可持续发展的必然之路,本文以固体废弃物无害化处置中常见的焚烧和填埋两种技术为例,以环境管理体系为视角,概述了固体废弃物生命周期中重要过程的环境因素识别和关键控制点等问题。
探析重金属污染土壤的修复技术及其修复效果评定
Authors: 刘 海龙
Published: July 2020

土壤是重要的自然资源,能够为农作物提供丰富的能源与养料,对促进农业产业的发展具有重要意义。工业废气的排放、人类生活污水的排放、汽车尾气的排放、过量使用农药等行为,都是造成土壤重金属超标的重要原因。为了保证人们身体健康和正常的生活,必须要做好重金属污染土壤的治理工作。鉴于此,文章就重金属污染土壤的修复技术及其修复效果进行了简要分析。
竞争攻击行为的影响因素实验
Authors: 王 英月
Published: July 2020

攻击行为是以伤害另一生命的身体或心理为目的的行为,即对他人的敌视、伤害或破坏性行为。本实验采用竞争反应时范式,2×2×2的被试间设计,探究图片启动线索(中性、攻击性)和攻击类型(主动、被动)及性别对大学生竞争攻击行为的影响。实验结果表明：(1)攻击类型对大学生的攻击行为没有显著影响；(2)图片启动线索对大学生的攻击行为有接近显著的影响,接受攻击性图片刺激的大学生比接受中性图片刺激的大学生更具攻击性；(3)性别对大学生的攻击行为有显著影响,男性大学生比女性大学生更具攻击性。日常生活中,在家庭、学校、集市等社会区域,人们都经常出现攻击行为,本实验有利于进一步研究攻击行为产生的原因及预防措施。
TRIZ理论在机械类专业创新能力培养模式构建
Authors: 单 武斌
Published: July 2020

随着我国进入新的发展阶段,产业升级和经济结构调整不断加快,各行各业对技术技能人才的需求越来越紧迫,高职学生作为新一代技术创新的主要力量,如何培养高职学生的创新能力显得至关重要。文章针对高职学生工程机械类专业技术创新能力现状分析,针对机械设计专业的人才培养方案、教学设计、考核体系等提出了看法和建议,并通过比赛的促进与激励,注重学生在学习、设计过程中的实践性体验,有效提高人才培养质量与职业岗位能力的匹配度,挖掘学生的创业潜能。
高校家庭经济困难学生的精准认定研究
Authors: 于 景琦 , 吕 征
Published: July 2020

高校资助育人工作是人才培养的重要环节,也是新时代精准扶贫思想政策的具体落实。现阶段我国高校资助工作面临着诸多困境,本研究旨在精准扶贫的视角下,通过广泛研究全省高校家庭经济困难学生认定工作的实践情况及现状,深度探究其中可能存在的问题和面临的挑战。同时基于高校认定工作的实际数据分析和调查研究,为高校家庭经济困难学生认定工作提供参考依据,使高校资助工作更加精准全面。
浅谈幼儿园主题墙的创设
Authors: 詹 晓冉
Published: July 2020

幼儿园的环境形形色色,每一处都对幼儿的发展有很大的影响,班级主题墙也不例外。它作为幼儿园中一个重要的墙面环境,对幼儿的健康发育也起到了很大的影响,其所发挥的教育价值也是非常之大。但是,尽管幼儿园的主题墙具有以上所述的众多教育价值,在真正实施布置的过程中,依然存在如下许多的不足：如主题墙所体现的教育目标模糊,幼儿的主体地位没有充分体现等。针对这一现状,可以通过明晰环境创设所要达到的目标,凸显幼儿的主体地位；重视环创的内容的选择,密切联系幼儿的活动；加强家长和幼儿园的有效互动,使材料更丰富几个方面来改善上述存在的问题。
试论教育的主要方式和主要内容——运用更好的教育 创造更好的明天
Authors: 张 紫峰
Published: July 2020

人在世界中,对一种事物由感官接触,到认知、理解的状态,并形成一种相对完善或理性的自我意识思维。教育的根本是以人的一种相对成熟或理性的思维来认知对待事物。教育既是传播知识与传授能力的过程,也是滋养心灵与培育人格的过程,影响每个人的成长,也影响世界的进步。我们研究教育的方式和教育的内容,在现实中可以运用更好的教育,创造更好的明天。
中学田径体育训练改革措施
Authors: 刘 洋
Published: July 2020

中学体育教学质量直接影响学生整体的身体素质,合理加强中学体育教学能够有效促进中学学生身心健康发展,在一定程度上提高了学生的综合素质,使教学效果得到最大化的提升。做好田径体育训练开展,则能够为学生身体素质的提升提供借鉴,能够让学生的身体素质得到提高。本文就中学田径体育训练改革路径进行探索,希望可以为中学田径教学的优化提供借鉴。
解析高中英语课堂教学的导入艺术
Authors: 高 健
Published: July 2020

课堂导入是课堂教学的基础,导入的合理性与否,关系着教学质量的高低,对学生知识的学习有着重大意义。高中作为教学的关键环节,为提高教学质量,合理应用课堂导入是非常必要的。本文以高中英语教学为出发点,对课堂导入艺术实行分析探讨,希望可以加深学生对英语知识的掌握。
《JavaScript语言》课程中思政元素的融合初探
Authors: 陈 冬梅
Published: July 2020

课程思政是一种综合教育理念,将思想政治工作贯穿教学始终,实现思政课和专业课的有机结合。文中以立德树人为根本任务,对计算机网络专业课程《JavaScript语言》课程中思政元素的融合进行了初步探究。
情景教学在对外汉语教学中的应用策略
Authors: 李 妍丽
Published: July 2020

当前在对外汉语教学中,情景教学受到大家的广泛关注,其直接性、互动性强的特点,使课堂教学变得更加生动有趣,激发学生的学习兴趣,这便于学生更好的解读和掌握相关知识。教师可以通过创造语言环境来培养学生语言运用、文化认知、发展想象等方面的能力,从而更好的推广我国汉语言文化。文章通过对情景教学的作用进行分析,总结出一些情景教学在对外汉语教学中的应用策略。
文字云图与批判性思维的培养
Authors: 胡 亚男
Published: July 2020

文字云图是一种基于词频的可视化工具,能够直观地显示词语密度和重要性。本文从批判性思维的重要性及其在教学中的发展现状入手,旨在探讨文字云图在阅读教学中的使用对于提高学生批判性思维的有效性和可行性。教师通过使用文字云图,设计出多样化的教学活动,多维度培养学生的批判性思维,推动英语教学的发展。
基于凸轮控制的无碳小车关键结构分析与设计
Authors: 肖 晓萍 , 张 立红 , 陈 聪聪
Published: July 2020

本文设计一种基于凸轮机构的双8字无碳小车。通过分析双8字运行轨迹及合理假设,建立了基于圆弧加三次B样条轨迹的数学模型,同时由估计各弧段长度设计凸轮特征参数,结合从动件推杆运动规律应用解析法建立凸轮轮廓线数学模型,利用MATLAB软件生成凸轮轮廓线,最后制作小车实物,通过测试验证了小车行驶平稳,轨迹重复精度较高,也说明了设计方法的可行性和正确性。
简析微课在中职Flash动画设计教学中的应用
Authors: 王 燕
Published: July 2020

在现阶段中等职业院校Flash动画设计教学过程中,广泛存在着重理论、轻实践的情况。且整体Flash动画设计教学方法较陈旧,不仅无法有效提高中职生学习知识的兴趣,而且抑制了中职生专业技能的有效提升。这种情况下,研究基于微课的中职Flash动画设计教学非常有意义。基于此文章探讨在Flash动画设计教学活动中如何开展微课教学,以期为相关教育学者提供一定的研究资料。
探析互动式教学法在中职园林3DMAX教学中的应用
Authors: 邬 月野
Published: July 2020

近年来有许多中职教师将各类教学法运用在课堂中,互动式教学法就是其中之一。互动式教学法中的师生互动、生生互动需要由课堂教学活动来引导。园林3DMAX教学中采用互动式教学法不仅可以让教师和学生更好地交流,还可以使学生更加积极主动地学习。基于此,本文就互动式教学法在中职园林3DMAX教学中的应用进行探析。
探讨高校体育公选课视阈下大学生对武术的认知水平——以北海艺术设计学院为例
Authors: 韩 传杰
Published: July 2020

本文根据北海艺术设计学院二年级学生在体育公共选课的时候,学生对武术认知程度进行了调查表明和结果显示：①大部分学生喜欢武术,对于北海艺术设计学院武术课程开设的必要性,大部分大学生对此十分认同；②当代大学生对武术的认知及其相关知识的途径,不仅是通过影视武侠剧(功夫片、动作片)、武术的电视节目、还通过武侠小说、武术表演节目及武术书籍或者视频等形式,认知渠道较为多样化；③当前高校武术教学目标基本吻合,但是大学生对于通过学习武术,了解中华武术的认知程度也较低。④我们应该通过教师专业素质和考核评价机制等因素,提高学生对学习武术兴趣。
大学生明礼意识养成教育现状及路径分析
Authors: 李 晓东 , 李 天娇
Published: July 2020

党的十八大以来,曾多次强调弘扬中华传统文化对涵养社会主义核心价值观的重要作用,在十九大报告中亦指出,深入挖掘中华传统文化蕴含的思想观念,人文精神,道德规范,结合时代要求继承创新,让中华文化展现出永久魅力和时代风采。明礼而知耻,崇德以向善。礼作为传统文化的重要组成部分,明礼与否是个人修养及社会文明程度的重要体现,国内外学者也普遍承认明礼对于个人修养和社会发展具有重要性。明礼强调的是社会之于人的外在规定性,大学生所具备的道德品质,是个体心理意识、习惯的养成,是内化的道德规范在具体行为中的外化展现。明礼意识养成教育丰富了养成教育理论,又深化了礼与伦理,礼与教育的理论研究,同时是大学生成才的重要因素,进行精神修养的重要内容,但当下大学生明礼意识养成教育中普遍存在理念缺位,内容不完善及方式趋于形式化等特点,同时也面临着社会转型期所带来的价值观浮躁,大学生自身道德困惑等挑战,对此现状,本文通过道德规范,时间活动及加强制度建设三方面进行路径分析。
大学生阅读习惯养成教育现状及路径分析
Authors: 李 晓东 , 李 天娇
Published: July 2020

当代大学生可选择的阅读条件和阅读方式越来越丰富,但大学生却面临着浅阅读、碎阅读甚至阅读量匮乏等阅读困境。党的十九大报告中提出“建设学习型社会”,2019年推动全民阅读第六次被写进《政府工作报告》,2019年8月21日,在考察读者出版社集团时强调,要提倡多读书,建设书香社会。9月9日,在给国家图书馆老专家回信中提出要“创新服务方式,推动全民阅读,更好满足人们精神文化需求。”这些改革措施充分体现了党和政府对于持续推进全民阅读的高度重视。大学生良好阅读习惯的养成是对大学生的素质教育,也会增加大学生的道德力量,起到对大学生思想政治教育的作用。本文即针对当下大学生阅读习惯养成教育所存在的问题进行探究并提出相应对策。
楼宇电气自动化控制系统的设计及应用探究
Authors: 章 群芳
Published: July 2020

楼宇自动化系统的主要运作方式是由中央计算机整合控制,各个控制子系统共同配合,是一种对综合性、整体性要求较高的自动化系统。在当前的楼宇自动化系统当中,主要采用的是传感技术,以及当前许多控制系统中会使用的现代通信技术。
初中化学生活化教学探究
Authors: 王 峰
Published: July 2020

教育的发展使得越来越多新的教学方法开始出现在教师的教学中,生活化教学策略就是其中之一。所谓生活化教学策略,就是教师在教学的过程中,结合知识引入生活元素,这种教学策略符合新课程改革的内容,能够有效地激发学生的学习兴趣,让学生了解知识学习的意义,提升学生的学习效果。基于此,本文将以初中化学为例,谈一谈初中化学生活化教学策略,希望能够为广大教师同胞们提供有效地借鉴。
高校实验室安全管理体系构建与实践
Authors: 苗 淼 , 刘 方卉竹
Published: July 2020

现阶段,高校缺少对实验室安全管理的重视性,同时缺少完善的安全管理体系。本文基于此展开研究,分析高校实验室安全管理所面临的新形势,主要讲述我国教育部门针对高校实验室安全问题所发布的新要求,并且在这基础上提出高校实验室安全管理体系的创建,从根本上解决高校实验室所面临的问题,解决高校的安全责任,完善高校实验室的安全健康建设。
地方理工院校外语本科专业应用型人才培养模式探究
Authors: 胡 金
Published: July 2020

基于桂林理工大学外语本科专业人才培养的前期调研,分析了该校外语本科专业应用型人才培养中存在的应用型人才缺乏全面深入研究、课程设置缺乏科学性和系统性等问题,剖析了问题存在的原因,提出地方理工科高校外语本科专业人才培养要在回归学科本位、加强人文教育的基础上,提升科学素养,找准专业定位,凝练专业特色,通过人才培养模式创新来实现应用型人才培养的目标。
Impact of Entrepreneurial Characteristics and Access to Credit on Business Performance of Small Business (Case: Brown Sugar Processing in Agam District)
Authors: Firnalista Nadia , Nofialdi  , Azriani Zednita
Published: July 2020

Small businesses' performance needs to be improved because it plays an essential role in driving economic growth and development. This study focuses on examining the effect of entrepreneurial characteristics on small business performance. Data was collected through a survey by giving questionnaires to 100 small business entrepreneurs processing brown sugar. Structural Equation Model (SEM) was chosen to ensure the relationship between variables. Empirical findings indicate that entrepreneurial characteristics affect business performance directly and indirectly through credit access, entrepreneurial characteristics affect credit access, and credit access affects business performance. Business performance improvement of brown sugar entrepreneurs needs government assistance and building networks.
The Role of Agricultural Extension in Increasing Competence and Income Rice Farmers
Authors: Managanta Andri Amaliel
Published: July 2020

The success of agricultural development in Indonesia in developing the ability of farmers is inseparable from the role of extension services carried out professionally. This study aims to (1) Analyzing the level of farmers 'perceptions about the role of extension workers in improving the competence of rice farmers in Tayawa Village, and (2) Analyzing factors that influence the level of farmers' perceptions about the role of extension workers in increasing the competence of rice farmers in Tayawa Village. This research uses a survey method with a descriptive analysis approach and a quantitative paradigm, supplemented with qualitative data information to support and sharpen quantitative analysis. The level of competence of middle rice farmers tends to be low, due to the weak role of agricultural extension workers. The role of the instructor as a communicator, facilitator, educator, and communicator turned out to have a positive effect on increasing the competence of rice farmers. But now these factors tend to be low so that it is still lacking in efforts to increase the competence of rice farmers.
MENINGKATKAN PEMAHAMAN BACA SISWA DENGAN REVIEW MENGGUNAKAN TEKNIK ISHIKAWA FISHBONE DI SMPN 1 TAJURHALANG BOGOR
Authors: Lisdawati Aprillia Putri
Published: July 2020

Memahami isi bacaan adalah hal terpenting dalam membaca. Namun, pemahaman siswa akan bacaannya masih sangat rendah. Mereview adalah salah satu cara yang dapat digunakkan dalam memahami isi bacaan. Salah satu teknik review yang dapat membuat siswa memahami bacaannya ialah teknik Ishikawa Fishbone. Teknik ini dapat membantu siswa dalam mengidentifikasi identitas buku, jenis bacaan dan grammatika maupun penambahan vocabulary (kosa kata bahasa inggris) siswa. Penelitian ini melibatkan 5 responden yang berasal dari kelas 9 di SMPN 1 Tajurhalang Bogor, dengan beberapa tahapan yaitu penjelasan, praktik pembuatan dan interview. Responden memiliki tanggapan yang sangat beragam, tetapi memiliki kecenderungan yang sama yaitu teknik Ishikawa Fishbone dapat membantu mereka dalam memahami bacaannya.
PROPOSAL PROGRAM KREATIVITAS MAHASISWA PEMBUATAN FLUME TANK SEDERHANA UNTUK PRAKTIKUM HIDRAULIKA DI FAKULTAS TEKNIK UNIVERSITAS IBN KHALDUN BOGOR
Authors: Insan Muhammad Khaerul , Ikhsan Muhammad , Adhyaksa Tirta
Published: July 2020

Flume tank atau tanki berarus adalah sebuah bentuk konstruksi alat yang dapat menampung air dalam jumlah tertentu dan dapat digunakan sebagai alat pengamatan, pengukuran maupun pengujian yang dilengkapi dengan arus air yang terkontrol. Pada proses perkuliahan hidrolika saluran terbuka dalam suatu instansi pendidikan tinggi perlu suatu media pembelajaran sebagai aplikasi teori yang dijelaskan pada materi perkuliahan, terkadang pada proses praktikum diperlukan kunjungan ke pihak yang bersedia dan memiliki alat praktikum yang akan digunakan sebagai media pembelajaran. Maka dari itu, penelitian ini bertujuan untuk membuat inovasi terbaru terhadap Flume Tank yang pada umumnya digunakan pada proses praktikum pembelajaran hidrolika saluran terbuka agar menjadikannya lebih praktis dan efisien di Fakultas Teknik Jurusan Teknik Sipil Universitas Ibn Khaldun Bogor.
Embolization of anterior cranial fossa dural arteriovenous fistula
Authors: Md Yusoff Bazli , Mohamad Jamali Ahmad Aizuddin , Abdul Haq Saifuddin Mohd Syafiek , Abdullah Mohd Shafie , Izaini Ghani Abdul Rahman
Published: July 2020

Dural arteriovenous fistulas (DAVFs) are abnormal connections between branches of the intracranial arteries and dural veins or sinuses. Advancements in the technique of endovascular embolization has made it the treatment of choice for DAVFs. The goal of treatment is to completely occlude the fistula orifice while maintaining the normal cerebral venous drainage. Depending on the site of the DAVF, endovascular treatment has its own challenges to the performing physician. In this case report, we will discuss complex anterior cranial fossa DAVFs, treatment approaches, and complications of the treatment.
Operational Methods for Charging of Electric Vehicles
Authors: Csonka Bálint , Havas Márton , Csiszár Csaba , Földes Dávid
Published: July 2020

The increasing number of electric vehicles induces a new relationship between the electric vehicles, transportation network and electric network. The deployment of the charging infrastructure is a prerequisite of the widespread of electric vehicles. Furthermore, the charging process and energy management have a significant influence on the operation of both the transportation and electric networks. Therefore, we have elaborated novel operational methods that support the deployment of charging infrastructure for electric cars and buses operating in public bus service, and the energy management. Weighted sum-models were developed to assess candidate sites for public charging stations. The mathematical model of public bus services was elaborated that supports the optimization of static charging infrastructure at bus stops and terminals without schedule adjustments. The flexibility and predictability of charging sessions were identified as the main differences between charging infrastructure deployment for cars and buses. Furthermore, the flows of energy, information and value have been revealed among the components of charging with a focus on commercial locations, which is the basis of energy flow optimization on the smart grid.
ПОДАТКОВА РЕФОРМА ЯК СПОСІБ ТРАНСФОРМАЦІЇ ПАРАДИГМИ ПОДАТКОВОЇ ДІЯЛЬНОСТІ ДЕРЖАВИ
Authors: Мацелюх Н. П.
Published: July 2020

Стаття присвячена розгляду податкової реформи як трансформації парадигми податкової діяльності держави через кардинальне переосмислення її призначення. Поглиблено аналіз дефініцій: ідеологія та політика податкової діяльності держави, податкова система. Здійснено аналіз сучасного стану податкової системи, визначено методологічні підходи до її реформування, запропоновано перелік завдань для вирішення в процесі податкової реформи, які сприятимуть пожвавленню розвитку економіки, підвищенню її ефективності.
ФІНАНСОВІ ІНКЛЮЗІЇ У БАНКІВСЬКІЙ ПРАКТИЦІ
Authors: Клименко Д. Б.
Published: July 2020

Банківський сектор завжди був на передовій технологічних змін. Наразі банки переживають один з найбільш масштабних етапів еволюції, що зазначає більшість сучасних науковців і практиків. Банки перестають бути тим місцем, куди клієнти приходять за грошима, перетворюючись на сервісні центри необхідних фінансових послуг. У банківському середовищі визначають не тільки рівень наданих послуг, а й рівень розробки технологій, які збільшують ступінь участі суспільства в цілому, кожного громадянина зокрема, спрощують процес взаємодії клієнтів з банком на основі інклюзії, тобто доступності. Більшість країн мають розроблену національну стратегію з фінансової інклюзії. Фінансово інклюзивне українське суспільство зможе розвинути нову фінансову екосистему на базі мобільних операторів, фінтек-компаній та інтернет-платформ.
БЮДЖЕТНЕ ФІНАНСУВАННЯ ВИДАТКІВ НА ОХОРОНУ ЗДОРОВ’Я: СУЧАСНИЙ СТАН ТА ТЕНДЕНЦІЇ РОЗВИТКУ
Authors: Лантух К. О.
Published: July 2020

У статті здійснено аналіз практики бюджетного фінансування видатків на охорону здоров’я за період 2014–2018 рр. Встановлено, що в останні роки в Україні отримали розвиток альтернативні форми залучення коштів до фінансування охорони здоров’я, зокрема добровільні лікарняні каси. Апробація нових моделей бюджетного фінансування медичних установ проводиться в ряді пілотних регіонів. Однак механізм бюджетного фінансування системи охорони здоров’я не зазнав суттєвих змін порівняно з радянським періодом. Обґрунтовано, що упродовж 2014–2018 років видатки зведеного бюджету України на охорону здоров’я збільшилися на 66,3 %, що має більше номінальний характер і пояснюється значними темпами інфляції, а не реальним зростанням видатків, оскільки у відсотковому відношенні до ВВП та загальних видатків зведеного бюджету видатки на охорону здоров’я не демонстрували зростаючої тенденції.
KANUNLARLA YASAKLANMIŞ İŞLERİN VERGİLENDİRİLMESİ VE KAZANÇ MÜSADERESİ
Authors: DURDU Muhammet
Published: July 2020

Vergiyi doğuran olayın kanunlarla yasaklanmış olması vergilendirmeyi nasıl etkileyecektir? Bu hususta Vergi Usul Kanunu, 9 uncu maddesinde açıkça, vergilendirmeyi etkilemeyeceği yönünde düzenleme yapmıştır. Fakat konusu suç olan veya kabahat teşkil eden bir fiil sebebiyle elde edilen gelirin vergilendirilmesi çeşitli sakıncalar doğurmaktadır. İlk başta, vergi hukuku, kanunla yasaklanmış fiilleri aklamış gibi bir izlenim ortaya çıkmaktadır. Ayrıca bu tür kazançlar hakkında kazanç müsaderesi veya mülkiyetin kamuya geçirilmesi tedbirinin uygulanması, fail hakkında, gerçekten bir kazanç elde etmeden vergi ödemesini gerektirebilmektedir. Bu husus caydırıcılık açısından faydalı gibi görünse de, vergiyi bir tür caydırıcılık unsuru olarak görmenin doğru olmadığı vurgulanmıştır. Ayrıca suç işlemiş bile olsa, bir kişi hakkında müsadere veya mülkiyetin kamuya geçirilmesi neticesinde iktisadi bir kazanç olmadan vergilendirme yapılması, vergi adaletine ve mülkiyet hakkına aykırı bir durumdur. Zira ekonomik yaklaşım ilkesi gereği duruma iktisadi açıdan bakılırsa, kazanç müsaderesine veya mülkiyetin kamuya geçirilmesine tabi tutulan bir gelir ortadan kalkmıştır ve vergilendirilecek bir kazanç yoktur.
Correlação matemática da massa específica da polpa de seriguela em diferentes temperaturas e estádios de maturação
Authors: Pereira Tamires dos Santos , Silva Virgínia Mirtes de Alcântara , Silva Lucas Rodolfo Inácio da , Luiz Márcia Ramos , Santos Newton Carlos , Almeida Raphael Lucas Jacinto , Ribeiro Victor Herbert de Alcântara , Muniz Cecília Elisa de Sousa , Eduardo Raphael da Silva , Silva Rebeca de Almeida
Published: July 2020

O objetivo do presente trabalho foi determinar a massa específica teórica da polpa de seriguela em diferentes temperaturas e estádios de maturação e ajustar aos dados obtidos funções polinomiais avaliando assim suas correlações matemáticas. As seriguelas foram classificadas em cinco diferentes estádio de maturação, o despolpamento aconteceu de forma manual, sendo utilizado nos experimentos o conjunto casca e polpa. A massa específica teórica foi calculada e os modelos matemáticos polinomiais foram ajustados aos dados da massa específica da polpa de seriguela em função da temperatura (25, 30, 35, 40, 45 e 50 °C) para cada um dos 5 estádios de maturação. Para o estádio de maturação I, a polpa apresentou aumento de 1035,88 para 1044,29 kg/m3; II de 1046,99 a 1055,50 kg/m3; III de 1053,95 a 1062,36 kg/m3; IV de 1062,94 a 1071,35 kg/m3; V de 1072,30 a 1080,71 kg/m3 em decorrência da diminuição da temperatura. A massa específica apresentou correlação positiva em relação ao avanço no estádio de maturação da polpa da seriguela e o inverso em relação a temperatura, sendo justificado pelo aumento da concentração no teor de sólidos solúveis totais. Os resultados foram representados por modelos matemáticos e o ajuste das funções polinomiais mostrou uma adequação satisfatória, no entanto o modelo com quatro termos apresentou o melhor ajuste com R2 igual a 1 para todos os estádios de maturação.
Caloric restriction and Spirulina platensis extract against ferrous ion (Fe2+) in the aging of Saccharomyces cerevisiae cells deleted to the SIR2 gene
Authors: Benetti Fábia , Dias Thanise Antunes , Costa Jorge Alberto Vieira , Bertolin Telma Elita
Published: July 2020

The aging process is aggravated by the presence of a high load of oxidative stress associated with the body's imbalance concerning certain metals, with emphasis on iron. Spirulina platensis extract (SP) and caloric restriction (CR) are nutritional interventions capable to mitigate the effects of aging-related diseases. The objective of this study was to determine the effects of SP and CR against ferrous ion on the aging of Saccharomyces cerevisiae deleted of SIR2 gene. Methods: Saccharomyces cerevisiae standard (WT) and sir2Δ strains, cultured in 2% or 0.5% (CR) glucose YPD media, whether exposed to 0.8 mg/mL SP and 1mM Fe2+. Cell viability and lipoperoxidation were analyzed. Results showed reduced cell survival and increased lipid peroxidation in the SIR2 gene deletion. Statistically significant results were found after aging for WT, SP, CR, SP + Fe2+, CR + Fe2+ treatments. The therapies CR and SP showed a protective effect against ferrous ion.
Long-Term Results of Enriched Environment and Erythropoietin After Hypobaric Hypoxia in Rats
Authors: HRALOVÁ M. , ANGEROVÁ Y. , GUEYE T. , BORTELOVÁ J. , ŠVESTKOVÁ O. , ZIMA T. , LIPPERTOVÁ-GRÜNEROVÁ M.
Published: July 2020

After global cerebral hypoxia, many patients are severely disabled even after intensive neurorehabilitation. Secondary mechanisms of brain injury as a result of biochemical and physiological events occur within a period of hours to months, and provide a window of opportunity for therapeutic intervention. Erythropoietin (EPO) has been shown to be neuroprotective in the brain subjected to a variety of injuries. Fifty-nine 3-month-old male Wistar rats were randomly distributed to experimental groups with respect to the housing (enriched environment – EE, standard housing – SH), to hypoxia exposure, and to EPO treatment. An acute mountain sickness model was used as a hypobaric hypoxia simulating an altitude of 8000 m. One half of the animals received erythropoietin injections, while the others were injected saline. Spatial memory was tested in a Morris water maze (MWM). The escape latency and the path length were measured. Better spatial learning in MWM was only seen in the group that received erythropoietin together with enriched environment. EPO administration itself had no influence on spatial memory. The results were very similar for both latencies and path lengths. These results support the idea that after brain injuries, the recovery can be potentiated by EPO administration combined with neurorehabilitation.
Saturated Hydrogen Saline Attenuates Endotoxin-Induced Acute Liver Dysfunction in Rats
Authors: XU X.-F. , ZHANG J.
Published: July 2020

To determine the effect of saturated hydrogen saline on lipopolysaccharide (LPS)-induced acute liver dysfunction, rats were divided into control, LPS, and LPS plus saturated hydrogen saline (LPS+H2) groups. Treatment with saturated hydrogen saline prolonged the median survival time and reduced liver dysfunction. Moreover, saturated hydrogen saline significantly reduced pathological alterations in liver tissues, the number of ballooned hepatocytes, serum tumor necrosis factor (TNF)-α and interleukin (IL)-6 levels, and myeloperoxidase (MPO) and malondialdehyde (MDA) levels in liver tissues (P<0.05). Cell apoptosis was detected in liver tissues after LPS treatment, and attenuated by saturated hydrogen saline treatment. Saturated hydrogen saline also decreased phosphorylated extracellular signal-regulated kinase (p-ERK), phosphorylated Jun kinase (p-JNK), nuclear factor-kappa B (NF-κB), and second mitochondria-derived activator of caspase (Smac) levels, and increased p38 activation (P<0.05). Thus, saturated hydrogen saline may attenuate LPS-induced acute liver dysfunction in rats, possibly by reducing inflammation and cell apoptosis. Mitogen-activated protein kinase (MAPK), NF-κB, and Smac may contribute to saturated hydrogen saline-mediated liver protection.
Neuregulin-1 Protects Against Doxorubicin-Induced Apoptosis in Cardiomyocytes Through an Akt-Dependent Pathway
Authors: AN T. , ZHANG Y. , HUANG Y. , ZHANG R. , YIN S. , GUO X. , WANG Y. , ZOU C. , WEI B. , LV R. , ZHOU Q. , ZHANG J.
Published: July 2020

In previous studies, it has been shown that recombinant human neuregulin-1(rhNRG-1) is capable of improving the survival rate in animal models of doxorubicin (DOX)-induced cardiomyopathy; however, the underlying mechanism of this phenomenon remains unknown. In this study, the role of rhNRG-1 in attenuating doxorubicin-induce apoptosis is confirmed. Neonatal rat ventricular myocytes (NRVMs) were subjected to various treatments, in order to both induce apoptosis and determine the effects of rhNRG-1 on the process. Activation of apoptosis was determined by observing increases in the protein levels of classic apoptosis markers (including cleaved caspase-3, cytochrome c, Bcl-2, BAX and terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) staining). The activation of Akt was detected by means of western blot analysis. The study results showed that doxorubicin increased the number of TUNEL positive cells, as well as the protein levels of cleaved caspase-3 and cytochrome c, and reduced the ratio of Bcl-2/Bax. However, all of these effects were markedly antagonized by pretreament with rhNRG-1. It was then further demonstrated that the effects of rhNRG-1 could be blocked by the phosphoinositole-3-kinase inhibitor LY294002, indicating the involvement of the Akt process in mediating the process. RhNRG-1 is a potent inhibitor of doxorubicin-induced apoptosis, which acts through the PI3K-Akt pathway. RhNRG-1 is a novel therapeutic drug which may be effective in preventing further damage from occurring in DOX-induced damaged myocardium.
Geometric Modeling of the Valencia Orange (Citrus sinensis L.) by Applying Bézier Curves and an Image-Based CAD Approach
Authors: Tinoco Hector A. , Barco Daniel R. , Ocampo Olga , Buitrago-Osorio Jaime
Published: July 2020

The computer-aided design of fruits are used for different purposes, e.g., to determine mechanical properties by applying engineering simulations, to design postharvest equipment, and to study the natural changes related to the topology. This paper developed a methodology to model Valencia orange (Citrus sinensis), applying Bézier curves and an image-based CAD approach; the orange geometry was designed for different ripening stages. In the modeling process, a 3D construction was carried out using third-order Bézier curves, adjusted to the images taken in orthogonal planes. Four control points defined each profile to compose the geometric pattern of the orange, with geometric errors lower than 3%. Two prediction models were proposed to relate the orthogonal dimensions with a factor size; this means that two dimensions out of three can be predicted. The results showed that the shape ratios kept constant in any ripening stage; however, the radius of curvature evidenced differences in the analyzed shape profiles. The methodological framework presented in the paper might be used to draw other types of citrus fruits. This contribution is a tool to model fruits in 3D, instead of using expensive technological equipment, since it is only necessary to apply computer design tools.
Evaluation of the Potential Effects of Drought on Summer Maize Yield in the Western Guanzhong Plain, China
Authors: Shen Hongzheng , Chen Yizheng , Wang Yongqiang , Xing Xuguang , Ma Xiaoyi
Published: July 2020

Drought and uneven distribution of precipitation during stages of crop growth exert a severe reduction on crop yield. It is therefore necessary to evaluate the impact of drought on crop yields. In this study, data from a two-year (2016 and 2017) field experiment were used to calibrate and evaluate the parameters of the Decision Support System for the Agrotechnology Transfer (DSSAT) model. The evaluation model was then employed to analyze the impact of potential drought on the yield of summer maize (Zea mays L.) over different growth stages for 46 years (1970–2015). The simulated summer maize flowering and harvest date differed by three and one days of the observed in 2017. The d-index value and the normalized root-mean-square error (nRMSE) of the simulated and measured values were 0.90 and 3.72%, 0.95 and 10.21%, and 0.92 and 13.12%, for summer maize yield, soil water content, and leaf area index, respectively. This indicates that the parameters of the DSSAT model were extremely reliable and that the simulation results were better. The yield reduction of summer maize was concentrated within the range of 0–40% from 1970 to 2015, and the two-stage yield reduction was higher than the one-stage yield reduction. The highest probability of yield reduction occurs if drought occurs during jointing and heading stages. Irrigation is therefore recommended during jointing stage or heading stage. If local irrigation conditions permit, irrigation can be carried out both at the jointing and heading stages. This study provides a theoretical basis for drought resistance management and scientific irrigation of summer maize in the western Guanzhong plain.