bluuebunny/crossref_metadata_2025 huggingface dataset:
IUCN Red List of Ecosystems, Mangroves of South India and Sri Lanka, and Maldives
Authors: Selvam Vaithilingam , Ramasubramanian R. , Kathiresan Kandasamy , Manoj Prasanna M.G. , Sunanda Kodikara K. A. , Amarasinghe Mala , Suarez Ena
Published: May 2024

Mangroves of South India and Sri Lanka, and Maldives is a regional ecosystem subgroup (level 4 unit of the IUCN Global Ecosystem Typology). It includes the marine ecoregions of Western India, South India and Sri Lanka, and Maldives. The mapped extent in 2020 was 249.2 km2, representing 0.2% of the global mangrove area. The environmental settings of this ecoregion differ widely ranging from open coast, lagoonal, deltaic and estuarine mangrove formations. The mangroves of Maldives grow on a calcareous mud substratum; those in all other parts of this ecoregion occur on fine terrigenous sediments. The biota is characterized by 21 species of true mangroves. The mangroves of the southernmost east coast of India are dominated by a single, highly saline-tolerant species: Avicennia marina. In contrast, elsewhere in this ecoregion, diverse species constitute the mangrove floral community. There are at least five endangered mangrove-associated bird species and one shark species in the IUCN Red List. The major threats to the mangroves of this ecoregion are reduction in freshwater flow and subsequent development of hypersaline conditions; conversion of mangroves for aquafarming and tourism development; changes in sediment dynamics; poor exchange of tidal water; and climate change especially sea-level rise and storm surges. Today the South India, Sri Lanka, and Maldives mangroves cover ranges between 197.1 and 249.2 km2 according to different available sources. This is higher than our broad estimation for 1970. The mangrove net area change fluctuates between -4.7 and -26.8% 1996 to 2020 based on the data sources. If this trend continues, an overall loss between 49% and 58 % is projected over the next 50 years. Under a high sea-level rise scenario (IPCC RCP8.5) 82.7% of this ecoregion’s mangroves would be submerged by 2060. Moreover, 3.2% of the mangroves are undergoing degradation, with the potential to increase to 9.5% within a 50-year period, based on a vegetation index decay analysis. Overall, the South India and Sri Lanka, and Maldives mangrove ecosystem is assessed as Critically Endangered (CR).
A Grid-based Framework for Managing Autonomous Vehicles' Movement at Intersections
Authors: Ghadi Maen
Published: May 2024

With a full fleet of autonomous vehicles (AV) in the future, the concept of signal-free intersections has attracted transportation researchers. Multiple studies have investigated different methods and protocols to facilitate vehicle decision-making at intersections. Most of these methods have relied on strong centralized or inter-vehicle communications. This research aims to develop a new protocol for managing vehicle movement at four-leg intersections assuming a fully automated fleet. The main concept of the proposed protocol is to maintain a continuous movement of vehicles entering the intersection, without stopping in queues, by controlling their sequence of movements. In the methodology a dynamic occupancy grid (DOG) approach is applied by initially dividing the intersection into dynamic grids (i.e. cells). The cells are in a virtual movement, emanating away from each lane-group without overlapping, like a gear machine. Each vehicle sits on a specific cell to traverse the intersection safely at a predetermined time. In other words, vehicles approaching an intersection must register their speed and position by certain sensors, and in return receive the appropriate acceleration and speed to finally be allocated to the suitable moving grids. The efficiency of the applied protocol was demonstrated by a practical example that presented a higher intersection capacity value exceeding the ideal saturation flow rate in some cases. This reflects the efficiency of the implemented protocol and its applicability to different low to high traffic flows. Moreover, the protocol shows more flexibility in dealing with different weather, geometric and traffic conditions.
Three dimensions advection-diffusion equation in unstable condition
Authors:   Mathematics and Theoretical Physics, Nuclear Research Center, Egyptian Atomic Energy Authority, Cairo-Egypt, ESSA Khaled S. M. , ELSAID Sawsan E. M. ,   Mathematics and Theoretical Physics, Nuclear Research Center, Egyptian Atomic Energy Authority, Cairo-Egypt
Published: May 2024

The advection-Diffusion Equation in three dimensions was solved using the Separation variable, Substitution and Laplace transform methods, taking into account that eddy diffusivity along the horizontal, lateral coordinates and wind velocity are constant respectively, while the vertical eddy diffusivity is a function of the vertical height "z", Monin- Obukhov length "L" friction velocity at different emission rate and operation of iodine (I-131) in an unstable condition. We took the measured data from Inshas, Cairo, Egypt and compared the concentration of the calculated results with the results obtained from the solution equation at heights of 0.7, 27, and 43 meters. We found that all models are within a factor of two with the observed data from statistical evaluations in unstable conditions, we found that all models fell into a factor of two with the observed data. Whereas with NMSE and FB, the current models correlate better with the observed data.
Obtaining of transdermal patches by means of natural active principles
Authors:   „Ion Holban“ Technical College, Iaşi, Roumania, ȘALARIU Mihaela , MOCANU Mihaela ,   „Gheorghe Asachi“ Technical University  of  Iaşi, Faculty of Chemical Engineering and Environmental Protection, Department of Organic, Biochemical and Food Engineering, Iaşi, Roumania
Published: May 2024

In the present paper the contributions are directed to obtaining transdermal therapeutic patches provided with a functional cotton textile support (acting as a reservoir) which would result in the controlled release of certain natural active principles (propolis and menthol), with .pharmaceutical action on people and children in order to support the treating and preventing of some irritations, wounds, injuries, scratches as well as certain allergic skin conditions in a natural, efficient and comfortable manner which would avoid the classic administration . In order to prove and characterize the inclusion of the active principles (propolis and menthol) into the cavity of the reactive cyclodextrin product grafted on the surface of the biofunctional textile support the following analytical methods were applied: scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and thermogravimetric analysis (TG-DTG).
Nonionic surfactant-templated mesoporous silica as supports for nickel active catalysts in liquid phase organic compounds oxidation
Authors:   “Ilie Murgulescu” Institute of Physical Chemistry, Roumanian Academy, Bucharest, Roumania, BALCAN Marieta , ANGHEL Dan F. ,   “Ilie Murgulescu” Institute of Physical Chemistry, Roumanian Academy, Bucharest, Roumania, NEGOESCU Daniela ,   “Ilie Murgulescu” Institute of Physical Chemistry, Roumanian Academy, Bucharest, Roumania, BRATAN Veronica ,   “Ilie Murgulescu” Institute of Physical Chemistry, Roumanian Academy, Bucharest, Roumania, PARVULESCU Viorica
Published: May 2024

Three surfactants were selected from a series of EOx/POy/EOx triblock copolymers and ethoxylated octylphenol as nonionic templating agents for the synthesis of silica mesoporous materials at room temperature and by hydrothermal treatment. The surfactants were ethylene oxide-propylene oxide-ethylene oxide tri-block copolymers (Pluronic F68) and a polydisperse ethoxylated octylphenol (Triton X-100). The obtained materials were compared with SBA-15 mesoporous silica synthesized with Pluronic P123 surfactant and were used as support to obtain Ni and NiTi-silica catalysts (2.5% NiO, 5% TiO2). The synthesized materials were characterized by X-ray diffraction, scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption, IR and UV-Vis spectroscopy. Catalytic and photocatalytic activity of Ni and NiTi-silica samples were tested, with and without H2O2, for phenol and Brilliant Blue FCF dye oxidative degradation in the liquid phase. The obtained results showed a significant effect of surfactant on silica structure, morphology and texture, and catalytic and photocatalytic properties.
Green inhibition of copper corrosion by ammoides verticillata oil in 1M nitric acid: weight lossand Raman spectroscopic mapping studies
Authors:   Laboratory of Catalysis and Synthesis in Organic Chemistry BP 119, University of Tlemcen, Algeria, CHABANE Naziha , DERGAL Fayçal ,   Laboratory of Catalysis and Synthesis in Organic Chemistry BP 119, University of Tlemcen, Algeria, ATTAR Tarik ,   Higher School of Applied Sciences of Tlemcen, BP 165, 13000 Bel Horizon, Tlemcen, Algeria, BELARBI Nadia ,   Center for Scientific and Technical Research in Physico-chemical Analyzes (CRAPC). BP 384, industrial zone 42004 Tipaza, Algeria, CHIKHI Ilyas ,   Laboratory of Catalysis and Synthesis in Organic Chemistry BP 119, University of Tlemcen, Algeria, CHARIGUI Samir ,   Laboratory of Catalysis and Synthesis in Organic Chemistry BP 119, University of Tlemcen, Algeria, MUSTAPHA Mohamed Abou ,   Center for Scientific and Technical Research in Physico-chemical Analyzes (CRAPC). BP 384, industrial zone 42004 Tipaza, Algeria, LERARI Djahida ,   Center for Scientific and Technical Research in Physico-chemical Analyzes (CRAPC). BP 384, industrial zone 42004 Tipaza, Algeria, BACHARI Khaldoun ,   Center for Scientific and Technical Research in Physico-chemical Analyzes (CRAPC). BP 384, industrial zone 42004 Tipaza, Algeria
Published: May 2024

The present study was designed to predict and analyze the effect of the essential oil of Ammoides verticillata (A.E.O) originating from the city of Souahlia (Tlemcen), which is located in northwest Algeria and its major compound on the inhibition of copper corrosion in 1 M HNO3. Gas chromatography coupled with mass spectrometry (GC-MS) revealed that carvacrol constitutes 67.89% of the essential oil. The study investigated the effect of concentration and temperature on copper corrosion and inhibitory efficiency using the gravimetric method. The findings indicate that A.E.O and carvacrol independently exhibit good inhibition properties on copper in 1 M HNO3, with the highest inhibitory efficiency at 1.5 g/L for A.E.O and 0.1 g/L for carvacrol, respectively. The adsorption of A.E.O and carvacrol on copper follows the Langmuir and Frumkin isotherm, respectively. The study also found competitive adsorption between iodide ions and A.E.O, as shown by the synergy parameter. Finally, Raman spectroscopy was used to analyze the immersed copper surface and mapping was used to characterize the surface layers in the different corrosive media used, which allowed us to develop a precise mapping of the corroded parts with the inhibited parts. This method will allow us to really see the inhibition effect of our materials.
Study on the performance of green corrosion inhibitor in protection of API5LX60 in seawater environment
Authors:   Departement of chemistry, Water and Environment Science and Technology Laboratory, Mohamed Cherif Messaadia University, Souk-Ahras, Algeria, SOBHI Nour El Houda , BOUKHOUIETE Amel ,   Departement of chemistry, university Badji-Mokhtar, Annaba, Algeria, FOUDIA Malika ,   Laboratory of energy and electrochemistry of solid (LEES), University Ferhat Abbas 1, Setif, Algeria, BENIDIR Sofiane ,   Laboratory  of Electrochemistry and Materials (LEM), Processes Engineering Dept., Faculty of  Technology, University Ferhat Abbas-Setif 1,  Setif, Algeria
Published: May 2024

The corrosion inhibition of metals in seawater can be achieved by the addition of inhibitors to the system that prevent corrosion from taking place on the metal surface. The effect of ascorbic acid on carbone steel corrosion in seawater were investigated by means of different techniques: gravimetric method, electrochemical polarization and electrochemical impedance spectroscopy and the scanning electron microscopy (SEM). The results obtained show that the acid ascorbic effectively inhibits the corrosion of steel X60. The optimal inhibitory efficiency is obtained at a concentration of 0.05 g/L of the inhibitor, with a maximum value of 77%. This inhibitor presents a mixed inhibition character. SEM studies confirm the absence of the deterioration products on the surface of the specimens.
inclusión educativa de alumnos con discapacidad en la escuela regular.
Authors: Vergara Fregoso Martha , Rivas Castañeda Rocío
Published: May 2024

El presente texto forma parte de la investigación dirigida a la indagación de los significados sobre la inclusión educativa de alumnos con discapacidad que refieren los profesores de escuelas primarias regulares, públicas, de una zona escolar en un municipio del estado de Jalisco, México, realizada en el año 2016.  Para ello se presentan algunos de los hallazgos sobre las vivencias y experiencias que han tenido los profesores y que comparten a través de la narración. Para la selección de los profesores que participaron en el estudio, se aplicó un cuestionario que aportó la información para la caracterización de cada uno de ellos, y posteriormente se realizaron entrevistas a profundidad a los 23 profesores de una zona escolar del municipio de Zapopan, Jalisco. Finalmente la información fue interpretada a partir de la fenomenología comprensiva.
Los hallazgos evidencian que los significados construidos por los profesores, reflejan las experiencias que han vivido a través de la atención de alumnos con discapacidad, de igual manera se pueden inferir algunos de los valores, éticos y profesionales que dan cuenta del compromiso moral, personal y profesional, entre otros aspectos.
Abstract from Current Literatures Vol. 46(3)
Authors: Editor The
Published: May 2024

Abstract not available
BANGLADESH J CHILD HEALTH 2022; VOL 46 (3) : 148-150
Association of Risk Factors with Female Pattern Hair Loss
Authors: Nasrin Tanjina , Wahab Md Abdul , Khondker Lubna , Safa Noor Ruhus
Published: May 2024

Introduction: Female Pattern Hair Loss (FPHL) is one of the main causes of hair loss in adult women and has a major impact on individual’s quality of life. It evolves from the progressive miniaturization of follicles that lead to a subsequent decrease of the hair density, leading to a non-scarring diffuse alopecia. In spite of the high frequency of the disease and the relevance of its psychological impact, its pathogenesis is not yet fully understood, being influenced by genetic, hormonal, and environmental factors. Objective: To evaluate etiological factors associated with female pattern hair loss. Materials & Methods: This was a hospital-based case control study, conducted in the Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU) from March, 2021 to August, 2022. In this study, total 100 females aged 18 to 45 years were enrolled. Among them, 30 females had history of hair loss >6 months, presented to outpatient department, BSMMU were included as case & 70 healthy females who had no history of hair loss included as control according to inclusion & exclusion criteria. Diagnosis of FPHL was made clinically & Ludwig classifications were used to assess the degree of hair loss. Information on possible risk factors for FPHL was collected using a questionnaire interview. Result: The mean age of the patients with FPHL was 41.0±7.77 years with majority belongs to >40 years of age group & their mean duration of hair loss was 26.3±12.0 months. Among the patients of FPHL, 36.7% had history of inadequate intake of iron containing food, 66.7% had family history of alopecia, 36.7% had history of increased bleeding during their menstruation, 20.0% had multiple (>3) childbirth & 23.3% had hypertension. About 86.7% patients with FPHL had low serum ferritin (<30ng/ml) with mean serum ferritin level was 20.25±16.07ng/ml and 66.7% patients of FPHL had low Hb (<12 µg/l) with mean Hb was 11.47±1.52 µg/l. In the multivariate logistic regression analysis significant association found with FPHL were age (OR 2.013, 95% CI 0.672-3.714), family history of alopecia (OR1.231, 95% CI 0.162-1.991) and lower serum ferritin level (OR1.090, 95% CI 1.043-1.139). Conclusion: Age, family history of alopecia, lower serum ferritin may be implicated as risk factors for female pattern hair loss.
Medicine Today 2023 Vol.36 (1): 7-11
Efficacy of Doxylamine and Pyridoxine during Pregnancy Induced Nausea and Vomiting
Authors: Rani Paul Tinni , Muzammel Hossain Khan Md , Paul Shukdeb , Nahar Amirun , Ahmed Estiak , Diba Chowdhury Farah
Published: May 2024

Introduction: Nausea and vomiting in pregnancy (NVP) is the most common medical condition of pregnancy causes a significant clinical, psychological and economic burden. Therefore, it is very important to treat this condition appropriately and effectively. The combination of Doxylamine and Pyridoxine is recommended as first-line therapy for nausea and vomiting in pregnancy. Objectives: To observe the therapeutic efficacy of combined Doxylamine and Pyridoxine for treatment of nausea and vomiting in pregnancy. Materials and Methods: An observational study was conducted on patients with nausea and vomiting in pregnancy attended the Model Family planning clinic in the Department of Obstetrics and Gynaecology, Sylhet MAG Osmani Medical College Hospital, Sylhet during the period from January 2019 to December 2019. A total 90 patients with clinically meaningful nausea vomiting (Pregnancy-Unique Quantification of Emesis [PUQE] score > 6) were selected and given 2-4 tablets each containing combined Doxylamine succinate 10 mg and Pyridoxine hydrochloride 10 mg based on a pre-specified titration protocol response to symptoms by respective physician and PUQE score was recorded in all participants before initiation of treatment and at 8th day and 15th day of treatment. In course of follow up period 7 patients were dropped out and finally 83 patients were analyzed in this study. Result: The mean PUQE score was decreased from 10.27 ± 1.76 to 7.94 ± 1.75 at 8th day and to 5.35 ± 1.47 at 15th day of treatment was significant (p<0.001). The percentage reduction of PUQE score was 23.14% at 8th day and 46.91% at 15th day of treatment. The difference was significant (p<0.001). Conclusion: Combined Doxylamine-Pyridoxine is effective and well tolerated in the treatment of nausea and vomiting in pregnancy (NVP).
Medicine Today 2023 Vol.36 (1): 26-30
La participación de la comunidad en la restauración del patrimonio material e inmaterial, ¿es posible?
Authors: García Olivares Gerardo Jesus
Published: May 2024

Se propone a partir de un caso aparecido en un periódico sobre la restauración de una imagen devocional las implicancias que tiene la restauración en la comunidad especialmente cuando se trata d piezas que están vinculadas al patrimonio inmaterial. Se hace hincapié en la posibilidades de realizar procesos participativos con la comunidad local para mejorar la toma de decisiones en el proceso de restauración. A partir de un texto como la Teoría Contemporánea de la Restauración se planta la necesidad de reflexionar sobre algunos de los conceptos monolíticos del campo de la Restauración aplicados al campo del patrimonio inmaterial o de aquellas obras materiales vinculadas a él como autenticidad, la objetividad, deterioro reversibilidad y legibilidad. También pretende proponer el debate si en las manifestaciones del patrimonio inmaterial se puede plantear la restauración o solamente acciones de salvaguarda y como la participación de los portadores resulta necesaria para que las intervenciones de restauración mantengan ese patrimonio colectivo activo desde una mirada más antropológica.
Presupuesto participativo como mecanismo para la distribución de los recursos públicos locales
Authors: Roa-Bustamante Juan , Miranda-Pichucho Freddy
Published: May 2024

Es importante solventar las incertidumbres acerca de la capacidad del presupuesto participativo para influir de manera significativa en la distribución de los recursos públicos, por esta razón, se planteó como objetivo de la investigación, interpretar el presupuesto participativo como un mecanismo de participación ciudadana para la eficiente distribución de recursos públicos locales, específicamente en los Gobiernos Autónomos Descentralizados cantonal, y parroquiales de Puyango. Empleando un enfoque cualitativo e inductivo, por medio de una revisión documental; para realizar la triangulación entre teorías y bibliografías revisadas, criterios de los autores y análisis de las entrevistas semiestructurada a actores claves. La investigación adoptó el enfoque descriptivo, profundizar los elementos y sus categorías, así como para entender el origen de los conceptos y sus significados. Los entrevistados jugaron un papel importante para fortalecer la información recabada sobre en la aplicación del presupuesto participativo, en la distribución de los recursos públicos tanto en el sector urbano y rural, donde la sociedad civil es crucial en la toma de decisiones. Para el análisis se utilizó la Teoría fundamentada, en conjunto con la hermenéutica, permitiendo interpretar comprensivamente la información proporcionada por los involucrados, la teoría y el criterio de los investigadores en la aplicación del presupuesto participativo a través de sus experiencias activas, permitiendo determinar cómo categorías emergentes a la participación ciudadana y su proceso, a los resultados y proyectos prioritarios, distribución equitativa entre lo urbano y rural, impacto de la infraestructura y los servicios, participación activa de las comunidades, logros y desafíos, y conciencia social.
¿En qué temáticas de la sostenibilidad hacen énfasis las empresas? Un estudio de caso de una empresa azucarera de Ecuador.
Authors: González-Márquez José , Reyes Victor , Sequera-Morales Adriana , Sánchez-Ancajima Raúl
Published: May 2024

La sostenibilidad se entiende como el paradigma dominante del presente siglo, donde se ha constituido en un requerimiento para las organizaciones. En este trabajo se explora la problemática del desempeño sostenible con el propósito de configurar clúster similares y homogéneos que resumen el reporte de la sostenibilidad de una empresa azucarera de Ecuador. Se revisó literatura de sostenibilidad, correspondientes al periodo 2012 – 2022, que fueron analizadas en cuanto a los componentes social, económico y ambiental. El trabajo tuvo un diseño explicativo y multivariado. La exploración del desempeño mediante una escala ordinal, demuestra que cumplen con los lineamientos de la “triple botton line”, evidenciándose un reporte integral, donde se destacan los aspectos económicos (serie GRI-200), el impacto social (serie GRI-400). También reportan las métricas ambientales (serie GRI-300). El desempeño evaluado a la empresa se realizó con base a los indicadores GRI, de donde se desprende un desempeño medio, que ha venido incrementándose en cuanto a mejoras y a número de contenidos, desde el año 2012. Se agruparon los 18 contenidos en dos clústeres (t de Student: p-valor. <0.05). El primero explica el 56.98% de la varianza. El segundo clúster/factor contempló una varianza explicada de 36.81%. El total acumulado fue de un 93.79% de varianza explicada, siendo esto un valor alto. Debido a lo que se deja de explicar, surge la necesidad de incorporar otras variables a los estudios multivariados. Se impone explorar e incorporar otros factores, para poder mejorar el modelo.
Palabras clave: medio ambiente, organización, sostenibilidad.
Estrategias digitales para la personalización de experiencias de viaje en la provincia Manabí
Authors: Sánchez-Cherres José , Zaldumbide-Peralvo David
Published: May 2024

El estudio se centra en cómo adaptar las experiencias de viaje en la región de Manabí, Ecuador, utilizando estrategias digitales, especialmente al identificar que la falta de uso efectivo y mejora de estrategias digitales representa un vacío importante que puede ser aprovechado para aumentar la satisfacción de los turistas y potenciar su valor turístico, esto significa que la industria turística se encuentra actualmente confrontando varios obstáculos. 
La metodología de estudio comprendió tanto técnicas cuantitativas como cualitativas, mediante la aplicación de encuestas a una muestra intencional de turistas que visitaron Manabí y de la encuesta a expertos en temáticas de turismo; para analizar la información obtenida en cuanto al reconocimiento de pautas de conducta, gustos y corrientes que individualizan y adaptan la vivencia durante los viajes, además de los puntos de vista, incentivos y vivencias personales subjetivas vinculadas con la integración de la tecnología y la personalización en la industria turística. Los resultados revelan que una correcta aplicación de estrategias digitales adaptadas a las necesidades de cada turista, tiene el potencial de influir en su decisión de visitar un destino turístico, elevar la satisfacción y su fidelidad, lo que a su vez puede impulsar el progreso sostenible y la competitividad de la industria turística a nivel local. 
Concluyendo en la necesidad de mejorar la infraestructura tecnológica existente, brindar programas de formación en competencias digitales a los profesionales del sector turístico y desarrollar estrategias que centralice y agrupe todos los recursos y servicios turísticos disponibles en la región.
Biological activity an in silico toxicity of phenolic compounds found in cupuaçu seed (Theobroma grandiflorum)
Authors: Ferreira Matheus Cardoso , Crispim Amanda do Egito , Aguiar Adma Maria Farias de , Lopes Anna Julia Santa Brígida , Correa-Barbosa Juliana
Published: May 2024

Cupuaçu (Theobroma grandiflorum) from the Malvaceae family, has seeds rich in flavonoids. The biological activities of seeds are diverse, however, there are scarce data on these metabolites. The study aimed to evaluate, through in silico methods, the biological, toxicological, and pharmacokinetic potential of metabolites present in the cupuaçu seed. The metabolites hypolaetina 3'-methylether 8-O-β-D glucuronide, theograndin II, hypolaetina 3'-methylether 8-O-β-D 3”-sulfated glucuronide, isoscutellarein 8-0-β-D glucuronide and theograndin I were analysed through Pubchem to search for structures, and PreADMET (pharmacokinetics and toxicity) and PASS online for biological activities (PA >98%). The results demonstrated low human intestinal absorption, in addition to weak to moderate distribution across the blood-brain barrier. All phenolic compounds showed weak to moderate binding to plasma proteins and low permeability in CaCo2 cells, except for isoscutelarein 8-0-β-D glucuronide and hypolaetina 3'-methylether 8-O-β-D glucuronide with moderate permeability, being non-mutagenic. Furthermore, they had the potential to inhibit CYPs, such as CYP-2C9 and CYP-3A4. Also, the structures showed toxicity in Medaka fish, but they did not present toxicity in algae and Daphnia sp. Finally, the molecules presented the following main properties: hemostatic, cardioprotective, and antioxidant action, among others. The compounds presented varied biological activity profiles, but their pharmacokinetic and toxicity were not promising, limiting the potential for developing new drugs. The use of technologies is suggested to transform them into prodrugs, carriers, and the use of molecular modeling.
Mortalidade por pancreatite aguda no Brasil no período de 2013 a 2023
Authors: Costa Rômulo Carvalho , Santana Maria Beatriz Porto , Santos Áleff Edrei Gomes , Muniz Filho Carlos da Silva , Silva Ana Victoria Lima Passos da , Dantas Maria Eduarda Pereira , Jesus Alícya Matias de , Rosa Daniel Maciel , Santos Vivyan Maria Lima
Published: May 2024

A Pancreatite Aguda (PA) é definida como uma doença inflamatória da glândula pancreática, devido a ação de enzimas inadequadamente ativadas, ocasionando edema, hemorragia e até mesmo necrose pancreática e peripancreática, assim, o objetivo deste estudo é analisar quantitativamente a quantidade de óbitos por pancreatite aguda nos hospitais brasileiros das cinco regiões do país, no período entre Janeiro de 2012 a Setembro de 2023. Metodologia: realizou-se um estudo epidemiológico transversal descritivo embasado no departamento de informação de saúde do SUS (DATA/SUS) utilizando as variáveis: internações hospitalares, taxa de mortalidade, óbitos, faixa etária, cor/raça, sexo, caráter de atendimento e macrorregião de saúde, média de internação hospitalar. Resultados: a pancreatite aguda provocou a morte de 19.867 brasileiros durante o período de 2012 a 2023. A partir da análise dos dados, pôde-se observar uma maior concentração do número de óbitos na região sudeste do país, de homens entre 60 e 69 anos. Conclusão: é possível que diversos fatores corroboram com esse achado, como as características sociais e demográficas, aspectos ligados ao estilo de vida e exposição ambiental, bem como melhor acesso aos serviços de diagnóstico, quando comparado com as demais regiões brasileiras.
PEMANFAATAN MEDIA YOUTUBE DALAM PEMBELAJARAN PAI BERBASIS DARING DI MASA PANDEMI COVID-19 UNTUK MENINGKATKAN HASIL BELAJAR PESERTA DIDIK KELAS VIII 7 SMP NEGERI 11 TANGGERANG SELATAN TAHUN 2021
Authors: Sadiyah Halimatus
Published: May 2024

Penelitian ini bertujuan untuk mengetahui Pemanfaatan media Youtube Terhadap Hasil Belajar Peserta Didik Dalam Pembelajaran PAI Pada Peserta Didik Kelas VIII 7 SMP Negeri 11 Kota Tangerang Selatan Tahun 2021. Tujuan penelitian dalam penelitian ini yaitu; Mendeskripsikan proses pemanfaatan media Youtube untuk meningkatkan hasil belajar peserta didik dalam pembelajaran PAI berbasis daring kelas VIII 7 SMP Negeri 11 Tanggerang Selatan; Mendeskripsikan peningkatan hasil belajar peserta didik kelas VIII 7 SMP Negeri 11 Tanggerang Selatan setelah memanfaatkan media Youtube dalam pembelajaran PAI berbasis daring. Penelitian ini menggunakan metode penelitian tindakan kelas, kegiatan dilaksanakan dalam dua siklus dengan tahapan; perencanaan, pelaksanaan, hasil dan refleksi. Teknik pengumpulan data menggunakan rubrik penilaian tes. Analisis data dalam penelitian ini bersifat kualitatif dan kuantitatif. Peningkatan hasil belajar peserta didik ditunjukan pada nilai rata-rata komparasi hasil belajar peserta didik pada prasiklus, siklus I, dan siklus II dengan nilai KKM 75. Pada kondisi awal peserta didik mendapatkan nilai rata-rata 61,34 dengan presentase 26,66% peserta didik yang tuntas, kemudian pada siklus I peserta didik mendapatkan nilai rata-rata 72,34 dengan presentase 54% peserta didik yang tuntas dan pada siklus II peserta didik mendapatkan nilai rata-rata 80,67 dengan presentase 100% peserta didik yang tuntas.
PENGARUH TINGKAT PENGETAHUAN, PERAWATAN DAN EDUKASI GURU TERHADAP KESEHATAN GIGI SISWA DI SDN PAKUHAJI V KABUPATEN TANGERANG
Authors: Sentosa Bambang Mardi , Farida Ida , Homalia Siti
Published: May 2024

ABSTRACT Background: The prevalence of 2016 Global Burden of Disease Study, dental and oral health problems, especially tooth decay, are diseases that affect almost half of the worldâ€™s population (3,58 Billion people). One of the causes of dental health problems in Indonesia is the lack of knowledge, care and education of the teachers. Purpose: to find out whether there is an effect of the knowledge, care and education of the teachers toward the dental health of the students SDN Pakuhaji V Kabupaten Tangerang. Research method: this research used quantitative causal with cross sectional approach. Proportionate stratified random sampling was used to obtain 153 respondents. Result of the research: according to the T-test, the level of the knowledge had no effect toward studentsâ€™ dental health, while care and education of the teachers had effect on it. Based on the result of F-test, the level of knowledge, care and education of the teachers had effect toward studentsâ€™ dental health simultaneously with F- table 2,67 and sig 0,000. Conclusion: there was the effect of the level of knowledge, care and education of the teachers toward studentsâ€™ dental health.
PENGARUH PENDIDIKAN, PENGETAHUAN DAN PENYULUHAN KESEHATAN TERHADAP PENURUNAN GLUKOSA DARAH PADA PASIEN DM TIPE 2 DIPUSKESMAS PAKUHAJI KABUPATEN TANGERANG
Authors: Farida Ida , Sentosa Bambang Mardi , Hapsah Siti
Published: May 2024

ABSRACT Background: According to WHO, diabetes mellitus is a degenerative disease that is experienced by many Indonesians, and its prevalence continues to increase from year to year along with its complications. Good knowledge of disease is a provision as the basis for the application of health behavior of DM patients in managing themselves to achieve a better quality of life. Health education has a goal to change behavior starting from changes in education and knowledge. Purpose: To determine the effect of education, knowledge and health education on reducing blood glucose in type 2 DM patients at the Pakuhaji Public Health Center, Tangerang Regency. Research method: : this research used quantitative causal with a cross sectional approach, the technique used is sampling jenuh as many as 65 respondents. Result of the research: Based on the results of the T test, the effect of education has no effect on the decrease in blood glucose, knowledge has an effect on the decrease in blood glucose, and counseling has an effect on the decrease in blood glucose. Based on the results of the F test, the effect of education, knowledge and health education on the decrease in blood glucose results in F table 2.36 with a sig value of 0.000. Conclusion: The results showed that there was an effect of education, knowledge and health education on reducing blood glucose.
Analisis Penerapan Sanksi Pidana Pelaku Residivis Tindak Pidana Narkotika
Authors: Irawan Benny , Raymond Hizkia
Published: May 2024

Abstract In positive law, narcotics crimes are qualified as extraordinary crimes, because the impact of these crimes has a dangerous situation that is widespread. Law No. 35 of 2009 is the basic rule for law enforcement officers to carry out law enforcement for perpetrators. In Article 54 of the Law it is explained that judges are obliged to consider conducting medical rehabilitation for drug users. In Decision No. 745/Pid. Sus/2018/PN Srg, the defendant is a drug case recidivist who had previously been rehabilitated. By using a normative juridical research method that uses the approach of legislation and legal principles, this study aims to examine and determine the application of punishment to recidives in Decision No. 745/Pid. Sus/2018/PN Srg by using the theory of judges' considerations and the purpose of sentencing. The results of this study are the application of sanctions against narcotics crime recidivists must use the purpose of punishment which results in a deterrent effect for the perpetrator, so that the perpetrator does not repeat the action.
SORBENTS BASED ON THE Ni,Fe-LAYERED DOUBLE HYDROXIDES AND ITS MAGNETIC NANOCOMPOSITES FOR DEACTIVATION AND PRECONCENTRATION OF Cs(I) AND Sr(II) IONS FROM AQUEOUS SOLUTIONS
Authors: Hubetska Tamara , Demchenko Victor , Kobylinska Natalia
Published: May 2024

The synthesis and comparative evaluation of the adsorption capacity in relation to Sr(II) and Cs(I) ions of the carbonate form of Ni(II)/­Fe(III)–layered double hydroxides (NiFe-LDH) and their nanocomposites was carried out. At first, Fe3O4 nanoparticles having a crystallite size of 20–50 nm were obtained by Fe(III) precursors. In the second step, Fe3O4 nanoparticles were embedded in NiFe-LDH matrix by the co-precipitation at hydrothermal conditions and subsequent condensation of the basic solution containing Fe3O4nanoparticles. The influence of the physicochemical parameters of the synthesized sorbents on the efficiency of magnetic solid phase extraction of these radionuclides from aqueous solutions was investigated. Their effectiveness in extracting Sr(II) and Cs(I) ions with a change in the pH of the aqueous medium was evaluated, as well as sorption isotherms on the obtained sorbents at pH0 4.5–5.0 were obtained, and their analysis and processing were carried out to establish the mechanism of sorption extraction at all le­vels of filling of the sorption layer with analytes. Equilibrium adsorption data were analyzed using Freundlich and Langmuir isotherm models. Of the models tested, Langmuir isotherm expressions were found to give better fit to the experimental data compared to the Freundlich model. The applicability of mathematical models for estimating the kinetic patterns of sorption of radionuclides on NiFe-LDH and their magnetic nanocomposites was analyzed. The adequacy of the Boyd and Morris – Weber diffusion models in the initial section (up to F = 0.4–0.6) of the kinetic curves is shown. Kinetically, the growth of effective diffusion coefficients and adsorption rate constants is observed in the series: Fe3O4<NiFe-LDH<Fe3O4@NiFe-LDH, and the pseudo-second-order kinetic model most accurately reflects the patterns of sorption of these radionuclides. Due to high sorption efficiency and manufacturability, the obtained sorbents are promising for water purification from radioactive pollutants.
IMPREGNATED ACTIVATED CARBON MATERIALS FOR RESPIRATORY PURPOSE. CHEMISORPTION OF SULFUR DIOXIDE
Authors: Khoma Ruslan , Vodzinskii Sergey , Klimov Danyil
Published: May 2024

The review is devoted to the use of impregnated activated carbon materials as chemisorbents of sulfur (IV) oxide. General methods for obtaining ordinary activated carbon, preparation of raw materials, their chemical activation with alkalis and acids followed by heat treatment (carbonization) in an inert environment or in the presence of a gaseous oxidizer, the role of acid-base and redox catalysts in this process are considered. The influence of the chemical composition of the  activated carbon surface, the presence of functional groups, and their acid-base properties, as well as the products of surface reactions on the peculiarities of sulfur (IV) oxide  adsorption is analyzed from the point of view of SO2 removal efficiency and the possibility of SO2 regeneration. An important role in these processes is played by the  pore size, the possibility of co-adsorption of water, and the presence of an oxidant. The nature of adsorbent-adsorbate interactions on the surface of activated carbon, their ener­gy, in particular, the contribution of so-called "physical" adsorption, van der Waals forces, hydrogen bonding, and the influence of surface functional groups are discussed. The activation of carbon raw materials with nitrogen-containing compounds leads to the N-doping of the surface, which increases the efficiency of SO2 adsorption, facilitating not only van der Waals and electrostatic interactions, but also S←N binding. The influence of oxygen and oxygen-containing functional groups on SO2 adsorption is also discussed.
To obtain impregnated activated carbon for SO2 absorption, the original activated carbon of the required quality is impregnated with solutions of inorganic and organic compounds that remain on the inner surface of the activated carbon after drying. Impregnation blocks partly  the porosity of activated carbon, but makes it more capable of chemical adsorption. Chemisorption, in which certain chemical bonds are formed between the surface of the activated carbon and the compound being adsorbed, is more selective than physical adsorption, where the size of  molecules is critical for an effective capture process. It can be noted that unlike inorganic alkalis, which spoil the porous structure of activated carbon, treatment with a solution of ammonia or organic N-containing bases promotes SO2 absorption. A special place in gas purification is occupied by activated carbon impregnated with ionic liquids, non-aqueous solvents being used for impregnation. A separate issue of the chemisorption of sulfur (IV) oxide by samples of impregnated activated carbon based on d-metals will be discussed in detail below.
THE LIFE AND CREATIVE PATH OF YURІY DELIMARSKYІ (ON THE OCCASION OF THE 120 OF THE BIRTH OF YURIY DELIMARSKYІ)
Authors: Omelchuk Anatoliy , Koval Larisa
Published: May 2024

The article is devoted to the 120th anniversary of the birth of Yu.K. Delimarskyі, Member of the Academy of Sciences of Ukraine, Doctor of Chemistry, professor, honored scientist of Ukraine, winner of the State Prize of Ukraine in science and technology, L.V. Pysarzhevsky Prize of the Academy of Sciences of the Ukrai­nian SSR, D.I. Mendeleev Gold Medal, a scientist widely known to the scientific community, in particular in the field of electrochemistry of ionic melts and solid electrolytes, one of the talented representatives of the "Kyiv School of Electrochemistry" and co-author of the scientific discovery "The phenomenon of metal transfer from the cathode to the anode during the electrolysis of ionic melts". The article presents some facts of Delimarskyi's biography, in particular his education, the period of his formation as scientist electrochemist; scientific achievements achieved by him, his students and followers in the field of electrochemistry of molten salts, chemistry and technology of inorganic substances and non-ferrous metals. Delimarskyi's personal memories of his work at the V.I. Vernadskyi Institute of General and Inorganic Chemistry of the National Academy of Sciences of Ukraine are peresented.
Pendidikan Agama Islam dan Kualitas Ekonomi Keluarga Muslim
Authors: Rifai Moh
Published: May 2024

This study aims to explore the relationship between Islamic religious education and the economic quality of Muslim families. Islamic religious education is an important aspect of Muslim life that plays a role in shaping their values, beliefs and religious practices. Meanwhile, the quality of the family economy is an important indicator to measure the welfare and sustainability of family life. The literature research method, which is also known as the literature research method, involves collecting, analyzing, and synthesizing information from various sources of literature that is relevant to answering research questions or understanding the topic under study. The results of this study indicate that there is a significant relationship between Islamic religious education and the economic quality of Muslim families. Families that have a higher level of Islamic religious education tend to have better economic quality. Islamic religious education can provide a strong moral and ethical foundation in managing family economic resources, avoiding behavior that is inconsistent with religious principles, and increasing sound financial understanding and practice. This finding has important implications for the development of Islamic religious education and programs that focus on the economic empowerment of Muslim families. Efforts to increase access to and quality of Islamic religious education can contribute to improving the economic quality of Muslim families as a whole. In addition, an approach that integrates aspects of Islamic religious education and finance can help develop financial literacy and good financial management among Muslim families. However, this study also acknowledges that there are other factors that can affect the economic quality of Muslim families, such as macroeconomic factors, level of general education, and access to economic opportunities. Therefore, further research is needed to deepen understanding of this relationship and other relevant factors.
ANALISIS PERAN MEDIA SOSIAL DALAM PENGHIMPUNAN DAN PELAPORAN DANA ZIS KEPADA MUZAKKI STUDI KASUS LAZISMU KABUPATEN PATI
Authors: Subkhan Andrean Fajar
Published: May 2024

Penelitian ini mengungkap tentang peranan media sosial dalam penghimpunan dan pelaporan dana ZIS kepada muzakki lazismu pati. Terdapat dua permasalahan dalam penelitian ini yaitu bagaimana peran penggunaan media sosial dalam penghimpunan serta pelaporan dana ZIS kepada muzakki dan dampak positif penggunaan media sosial dalam penghimpunan dan pelaporan dana ZIS kepada muzakki. Untuk menjawab pertanyaaan tersebut peneliti menggunakan metode kualitatif dengan memperoleh datanya dari hasil wawancara, observasi dan dokumentasi. Hasil penelitian menunjukkan bahwa media sosial memiliki peranan yang sangat penting dalam kegiatan penghimpunan dan pelaporan dana ZIS kepada muzakki. Salah satunya yaitu dengan adanya media sosial, proses penghimpunan dana ZIS lebih optimal, serta dalam memberikan laporan-laporan terkait dana ZIS yang terhimpun kepada muzakki menjadi lebih mudah, sehingga para muzakki atau donatur bisa mengetahui dana yang telah mereka berikan digunakan untuk apa saja. Selain itu, dampak positif yang dirasakan adalah mempermudah mencari donator, Dapat memberikan atau menyebarkan informasi yang ada di LAZISMU Pati, mempermudah LAZISMU dalam mempererat silaturahim dengan para donator, dan Dapat meningkatkan kepercayaan masyarakat terhadap LAZISMU Pati.
Assessment of the content of short-chain fatty acids in ulcerative colitis as an indicator of the patient's metabolic health
Authors: Bikbavova G. R. , Livzan M. A. , Lisyutenko N. S. , Romanyuk A. E. , Indutny A. V. , Martynenko O. V.
Published: May 2024

Numerous studies show that in the pathogenesis of ulcerative colitis (UC), a significant role is played by a change in the diversity of the intestinal microflora, which is associated with fewer bacteria producing short-chain fatty acids (SCFAs). SCFCS affect the differentiation and activation of cells of the immune system, play a protective role in maintaining the integrity of the epithelial barrier, participate in the regulation of intestinal peristalsis and blood supply to its wall, muscle anabolism, bioavailability of amino acids.

The aim of the study. To evaluate the content of SCLC in the feces of UC patients with varying degrees of severity of the current attack, as well as to investigate the relationship between the content of SCLC with dietary characteristics, body mass index (BMI), and dyspenia.

Materials and methods. The study involved 80 UC patients, conducted a survey, objective examination, filling out medical history and outpatient records, blood and stool sampling. The content of SCLC was determined in feces. The study of nutritional characteristics in patients with UC was conducted using a standardized questionnaire of the WHO CINDI program. Statistical methods: median (Me), upper and lower quartiles (P25, P75) were calculated; Mann-Whitney criterion; Kolmogorov-Smirnov criterion; nonparametric correlation analysis was performed.

Results. The absolute content of SCFCS in the feces of patients with UC is lower than the reference values. The relative content of propionic acid in the subgroup with severe attack was significantly lower than in the remission subgroup, in the subgroup with mild and moderate attack of the disease. In patients with body weight deficiency, the relative content of propionic acid is lower than in UC patients with normal or overweight. A positive relationship was found between the total content of SCFCS in feces and the amount of dietary fiber consumed in the form of fruits and vegetables. In patients with dinapenia, the relative content of butyric acid in feces is significantly lower than in patients without dinapenia.
Side effects of proton pump inhibitors with long-term use: focus on the urinary system
Authors: Trukhan D. I. , Viktorova I. A.
Published: May 2024

Proton pump inhibitors (PPIs) are the most effective drugs for treating acid-related diseases. In recent decades, the use of PPIs has increased exponentially. For a long time, PPIs were considered completely safe drugs for both short-term and long-term use. However, modern clinical guidelines note that when prescribing PPIs in large doses for a long period, the possibility of side effects should be taken into account. In recent years, a number of foreign reviews have been published that examine the associations between PPIs and a number of diseases/conditions. We searched the PubMed and Scopus information databases for publications on the safety of PPI use, including sources up to January 30, 2024. In this review, we examined the effect of long-term use of PPIs on the urinary system. This review demonstrates possible changes in the urinary system and an increased risk of developing nephrolithiasis, acute interstitial nephritis, acute kidney injury, chronic kidney disease, end-stage renal failure with long-term use of PPIs, which should certainly be taken into account when prescribing them for a long period, especially in patients with comorbid pathology.