bluuebunny/crossref_metadata_2025 huggingface dataset:
Um Sentido para a Experiência Escolar em Tempos de Pandemia
Authors: Carvalho José Sérgio Fonseca de
Published: January 2021

Resumo: No presente artigo a emergência da pandemia global é analisada como um fator que torna ainda mais visível e aguda a crise da educação. Isso ocorre porque à não presencialidade espacial dos alunos agrega-se o esvaziamento da dimensão temporal da educação. Esse esvaziamento é tratado a partir da narrativa da experiência escolar de uma adolescente. Sua interpretação e análise apontam para a necessidade de a experiência escolar propiciar a seus alunos a oportunidade de habitarem um outro mundo no tempo e no espaço por meio do acesso e da ressignificação de obras ficcionais e historiográficas nas quais a experiência de viver uma pandemia seja reconfigurada à luz do presente.
Negação da Política e Negacionismo como Política: pandemia e democracia
Authors: Duarte André de Macedo , César Maria Rita de Assis
Published: January 2021

Resumo: O texto se desenvolve em três etapas complementares: primeiro, discutimos a estratégia da negação da política, com a qual Bolsonaro afrontou valores democráticos sem romper definitivamente com a democracia, tanto na campanha presidencial como na pandemia. No segundo momento, discutimos a estratégia do negacionismo como política, importante para a compreensão do modo como Bolsonaro empreendeu sua gestão da pandemia. No terceiro momento, argumentamos que durante a pandemia aquelas duas estratégias se conjugaram, produzindo fenômenos sócio-políticos que corroem a democracia, como a banalização das mortes e a naturalização da clivagem entre vidas valiosas, vidas submetidas a processos de menos-valia e vidas descartáveis.
Mais uma Lição: sindemia covídica e educação
Authors: Veiga-Neto Alfredo
Published: January 2021

Resumo: Este artigo articula os desdobramentos das crises geradas pela pandemia da COVID-19, com as deficiências da educação escolar, no Brasil. Argumenta que uma escola marcada por desigualdades, exclusões, elitismo, facilitação e superficialidade vem gerando amplos contingentes de estultos e refratários às orientações científicas de prevenção à pandemia e seu controle. Tal situação é agravada por parte das classes políticas dirigentes, cujos líderes são fiéis adeptos do negacionismo, fundamentalismo político e religioso, anticientificismo e conspiracionismo. Propõem-se alguns princípios norteadores para a educação científica com ênfase nas dimensões gnosiológica e formativa. É feita uma revisão da nomenclatura usada pelos estudos sobre pandemias.
Comunicação Educativa: perspectivas e desafios com a COVID-19
Authors: Escola Joaquim José Jacinto
Published: January 2021

Resumo: A reflexão sobre a comunicação educativa instiga-nos a refletir sobre a importância da comunicação humana e das mediações tecnológicas na educação. A situação pandémica que atinge o mundo colocou-nos um conjunto de desafios sem paralelo. A história da comunicação, (Cloutier, 2001) bem como a periodização das tecnologias na educação (Costa, 2007) comprovam uma estreita relação entre os tipos de comunicação, os dispositivos utilizados, e as respostas disponibilizadas pela comunicação educativa em face dos desafios que a COVID-19 colocou, tendo como pano de fundo o contexto de ensino português.
Maternal and fetal outcomes of pregnancy in chronic kidney disease: diagnostic challenges, surveillance and treatment throughout the spectrum of kidney disease
Authors: Gouveia Inês Filipe , Silva Joana Raquel , Santos Clara , Carvalho Claudina
Published: January 2021

Abstract Pregnancy requires several physiological adaptations from the maternal organism, including modifications in the glomerular filtration rate and renal excretion of several products. Chronic kidney disease (CKD) can negatively affect these modifications and consequently is associated with several adverse maternal and fetal adverse outcomes (gestational hypertension, progression of renal disease, pre-eclampsia, fetal growth restriction, and preterm delivery). A multidisciplinary vigilance of these pregnancies is essential in order to avoid and/or control the harmful effects associated with this pathology. Dialysis and transplantation can decrease the risks of maternal and fetal complications, nonetheless, the rates of complications remain high comparing with a normal pregnancy. Several recent developments in this area have improved quality and efficacy of treatment of pregnant women with CKD. This article summarizes the most recent literature about CKD and pregnancy.
Bilateral renal infarction in a patient with severe COVID-19 infection
Authors: Añazco Percy Herrera , Balta Fernando Mayor , Córdova-Cueva Liz
Published: January 2021

Abstract Thromboembolic events are frequent in patients with COVID-19 infection, and no cases of bilateral renal infarctions have been reported. We present the case of a 41-year-old female patient with diabetes mellitus and obesity who attended the emergency department for low back pain, respiratory failure associated with COVID-19 pneumonia, diabetic ketoacidosis, and shock. The patient had acute kidney injury and required hemodialysis. Contrast abdominal tomography showed bilateral renal infarction and anticoagulation was started. Kidney infarction cases require high diagnostic suspicion and possibility of starting anticoagulation.
Terminologia especializada de enfermagem para cuidado à pessoa com insuficiência cardíaca crônica
Authors: Nascimento Maria Naiane Rolim , Moreira Antonia Elizangela Alves , Ramos Natana de Morais , Gomes Emiliana Bezerra , Félix Nuno Damácio de Carvalho , Oliveira Célida Juliana de
Published: January 2021

Resumo Objetivo Construir uma terminologia especializada de enfermagem para o cuidado à pessoa com insuficiência cardíaca crônica. Método Estudo metodológico, realizado em duas etapas: identificação dos conceitos relevantes em artigos científicos relacionados à prioridade de saúde eleita e mapeamento cruzado dos conceitos identificados com os conceitos da CIPE®. Resultados Extraíram-se 333 conceitos únicos úteis ao cuidado de enfermagem relacionado à afecção em questão, logo submetidos à etapa do mapeamento cruzado com os conceitos da CIPE® 2019-2020. Foram classificados 201 conceitos como constantes e 132 não constantes. Na análise de similaridade e abrangência, 85% foram classificados como iguais e 15% similares. Os conceitos não constantes caracterizaram-se 44% como mais abrangentes, 11% mais restritos e 45% sem concordância. Quanto à classificação dos conceitos nos sete Eixos da CIPE®, caracterizou-se por Eixo Foco (50%), Eixo Julgamento (13%), Eixo Meio (12%), Eixo Ação (10%), Eixo Localização (9%), Eixo Tempo (4%) e Eixo Cliente (2%). Conclusões e implicações para a prática Foi possível construir terminologia especializada de enfermagem com base na CIPE® para o cuidado à pessoa com insuficiência cardíaca crônica, em que 40% dos conceitos que compõem a terminologia não estão constantes na versão 2019-2020 da classificação, sendo passíveis de inserção em versão posterior.
A Percepção e o Discurso de Jovens Brasileiros sobre os Partidos Ecológicos
Authors: Barros Antonio Teixeira de , Mitozo Isabele Batista
Published: January 2021

RESUMO O artigo tem por objetivo analisar como os partidos ecológicos são vistos pelos jovens no Brasil e, consequentemente, qual o perfil dos eleitores dessas legendas. Para tanto, realiza um estudo exploratório a partir da aplicação de um questionário a 710 informantes. Para analisar os dados, o aporte teórico utiliza contribuições da sociologia político-ambiental e da sociologia da juventude. Dentre os resultados obtidos a partir do cruzamento de variáveis, pode-se constatar que conhecer o partido e suas propostas, estar em faixa etária jovem mais avançada, assim como ter maior nível de escolaridade e renda familiar se associam positivamente ao voto de jovens nos partidos ecológicos. Conclui também que os vínculos sociais continuam relevantes para a construção social da reputação política dos partidos, uma vez que os jovens tomam conhecimento das propostas das agremiações (sobretudo, PV e REDE) por meio de seu círculo de amigos.
MULHERES EM HOME OFFICE DURANTE A PANDEMIA DA COVID-19 E AS CONFIGURAÇÕES DO CONFLITO TRABALHO-FAMÍLIA
Authors: LEMOS ANA HELOÍSA DA COSTA , BARBOSA ALANE DE OLIVEIRA , MONZATO PRISCILA PINHEIRO
Published: January 2021

RESUMO Esta pesquisa objetivou compreender os impactos que a adoção do home office, no período da quarentena da Covid-19, teve no conflito trabalho-família vivida por trabalhadoras brasileiras. Para alcançar o objetivo, foram entrevistadas 14 profissionais com diferentes arranjos familiares. Todas as entrevistadas relataram sobrecarga de trabalho devido às exigências organizacionais, às demandas com os filhos e com a casa. Apesar disso, cabe destacar que, de acordo com os depoimentos, a sobrecarga de trabalho não intensificou o conflito trabalho-família para todas, o que vai na contramão do previsto na literatura. Algumas entrevistadas alegaram que o home office aproximou-as dos filhos e maridos e propiciou mais tempo para atividade físicas e de lazer. Tal achado pode contribuir para ampliar o debate sobre o conflito trabalho-família, muitas vezes conflituosa, ao postular que não apenas o tempo, a pressão e o comportamento são fontes deste conflito, mas também a distância física que as horas dedicadas ao trabalho fora de casa requerem.
EFEITOS DA INFORMAÇÃO NA INSEGURANÇA E ENGAJAMENTO NO TRABALHO EM TEMPOS DE PANDEMIA
Authors: FRARE ANDERSON BETTI , BEUREN ILSE MARIA
Published: January 2021

RESUMO Pandemias suscitam cenários de incerteza que afligem até mesmo pessoas acostumadas a promover congruên cia de informações, como em empresas fintechs. Assim, objetiva-se investigar os efeitos do compartilhamento vertical da informação na mitigação da insegurança no trabalho e no engajamento no trabalho, moderada pela credibilidade da informação de mídias sociais sobre pandemia. Uma survey foi realizada com funcionários da maior startup financeira brasileira e, na análise dos dados, aplicou-se modelagem de equações estruturais e fuzzy-set QCA. Os resultados apontam que compartilhamento vertical da informação mitiga insegurança no trabalho e exerce efeitos no engajamento no trabalho. Compartilhamento vertical da informação e ausência da insegurança são, respectivamente, quase sempre e sempre necessárias, e suficientes para alto engajamento no trabalho. Ademais, a credibilidade da informação modera a relação entre insegurança e engajamento no trabalho. Esses resultados proporcionam contribuições ao revelar efeitos de antecedentes da insegurança e do engajamento no trabalho num período singular de pandemia.
ATUAÇÃO EMPRESARIAL PARA SUSTENTABILIDADE E RESILIÊNCIA NO CONTEXTO DA COVID-19
Authors: NICOLLETTI MARIANA , ALEM GABRIELA , BLAZEK MARTA , FILLIPPI PAOLA , BISMARCHI LUIS FELIPE
Published: January 2021

RESUMO O enfrentamento da crise da Covid-19 ressaltou a importância do olhar crítico e sistêmico para a atuação empresarial para sustentabilidade. Este artigo tem como objetivo discutir a sustentabilidade, através das lentes teóricas de sustentabilidade “forte” e “fraca” e suas relações com os paradigmas econômicos; apresentar a teoria da resiliência como alternativa frente aos atuais desafios; e analisar, com base nos conceitos apresentados, indícios de como as organizações estão reagindo inicialmente, em suas atuações com sustentabilidade, à crise da Covid-19. Para tanto, foram realizadas entrevistas semiestruturadas com empresas que atuam no Brasil. Como resultado, indícios de realinhamento ao propósito inicial da empresa de criar valor para a sociedade coexistem com indícios de continuidade da aposta em soluções via mercado e da busca por crescimento infinito em um planeta com recursos limitados.
THE BURNOUT EPIDEMIC DURING THE COVID-19 PANDEMIC: THE ROLE OF LMX IN ALLEVIATING PHYSICIANS’ BURNOUT
Authors: MOURA EDUARDO CARDOSO DE , FURTADO LILIANE , SOBRAL FILIPE
Published: January 2021

ABSTRACT During COVID-19 pandemic, physicians are being exposed to unprecedented adverse working conditions that lead to increased occurrence of burnout. While supportive leadership is considered effective in preventing burnout, little is known about the role of leadership in extreme situations. Drawing on leader-member exchange (LMX) theory, we hypothesize that high-LMX relationships lead to lower levels of burnout, as they shape physicians’ perceptions of psychosocial job demands and resources. We also contend that this effect will be stronger for frontline physicians, as they are more exposed to job stressors. In a field study with 2,708 Brazilian physicians, we found support to the alleviating role of LMX, but contrary to what we predicted, we found that this effect is weaker for frontline physicians. Overall, our findings reinforce the importance of establishing high-quality relationships between supervisors and medical staff to mitigate the experience of burnout, however, they also highlight that extreme conditions, such as the COVID-19 pandemic, might constrain the beneficial effects of leadership behaviors.
Source-sink relationships of wheat plants obtained by the application of systemic herbicides
Authors: Fioreze Samuel Luiz , Drun Robson Pelissari , Wuaden Ana Flávia , Mazzuco Volni , Oliveira James Cruz de
Published: January 2021

Abstract: The objective of this work was to evaluate the potential of solute translocation among stems of wheat (Triticum aestivum), by the application of the systemic herbicides clethodim and glyphosate. The experiments were carried out in greenhouse conditions, using wheat cultivars with contrasting potential for tillering, during the winter of 2017 and 2018 in Southern Brazil. Clethodim was applied on isolated stems, to evaluate the potential translocation of solutes from the first three tillers. Translocation was evaluated by the yield parameters on stem ears not treated with clethodim. Glyphosate was used to evaluate the potential translocation of solutes from late tillers. Translocation was evaluated by the assimilation of carbon in stems without the glyphosate treatment. When applied on isolated primary tillers, clethodim reduced yield parameters only in treated stems, which shows that the assimilates were targeting the main sink, in detriment of the other organs. There was a decrease in net carbon assimilation in stems without the glyphosate treatment at the first visible node stage. Glyphosate applied on late tillers, at anthesis, reduced even more net carbon assimilation in nontreated stems of the primary tillers of the BRS Parrudo wheat cultivar (low tillering). Well-developed late tillers show higher potential of solute translocation to the whole plant than the poor-developed ones.
Discrimination of responses of corn genotypes to drought through physiological, growth, and yield traits
Authors: Santos Thiago Teixeira , Casari Raphael Augusto das Chagas Noqueli , Molinari Hugo Bruno Correa , Kobayashi Adilson Kenji , Souza Júnior Manoel Teixeira , Silva Vivianny Nayse Belo , Ferreira Thalita Massaro Malheiros , Sousa Carlos Antônio Ferreira de
Published: January 2021

Abstract: The objective of this work was to evaluate different traits of four corn (Zea mays) genotypes with contrasting responses to drought and to determine the main traits associated to such responses. The experiment was carried out in a greenhouse. The plants were grown in pots subjected to full irrigation. Drought was imposed to plants at 54 days after sowing and kept constant for 12 consecutive days; however, a group of plants remained under full irrigation. Traits related to leaf gas exchange, photochemical apparatus, growth, and yield were assessed, and data were subjected to hierarchical agglomerative clustering and principal component analysis. DKB 390 distinguishes from the other genotypes for growth and yield traits, while 2B-707 and DKB 390 discriminate from 'BRS 1030' and 'BRS 1010' for physiological traits. Ear length, kernel number per ear, above-ground dry matter, shoot dry matter, and plant height are the most important growth and yield traits to discriminate genotype-dependent drought tolerance. Among the physiological traits, the most important are: chlorophyll content, absorptivity, leaf temperature, maximum fluorescence in the dark-adapted state, minimum fluorescence in the dark-adapted state, water-use efficiency, and intercellular CO2 concentration.
The Unusual Composition of Demand during the Pandemic
Authors: Aladangady Aditya , Garcia Daniel
Published: January 2021

In most recessions, household spending on goods—particularly durables—and housing tends to fall sharply and remain weak for many quarters. In contrast, services spending has generally responded little to business cycles. This time, however, the opposite has occurred, as shown in Figure 1.
Problem of the Vertical Deflection in High-Precision Inertial Navigation
Authors:   Concern CSRI Elektropribor, St. Petersburg, Russia, Peshekhonov V.G. ,   ITMO University, St. Petersburg, Russia
Published: January 2021

The paper addresses the systematic error of an inertial navigation system, caused by the discrepancy between the plumb line and the normal to the reference ellipsoid surface. The methods of this discrepancy estimation, and their use for correcting the output data of inertial navigation systems are studied.
Strapdown Attitude Computation: Functional Iterative Integration versus Taylor Series Expansion
Authors:   Shanghai Jiao Tong University, Shanghai, China, Wu Y. , Litmanovich Y.A. ,   Central Scientific and Research Institute “Elektropribor”, Saint Petersburg, Russia
Published: January 2021

There are two basic approaches to strapdown attitude computation, namely, the traditional Taylor series expansion approach and the Picard iterative method. The latter was recently implemented in a recursive form basing on the Chebyshev polynomial approximation and resulted in the so-called functional iterative integration approach. Up to now a detailed comparison of these two approaches with arbitrary number of gyroscope samples has been lacking for the reason that the first one is based on the simplified rotation vector equation while the second one uses the exact form. In this paper, the mainstream algorithms are considerably extended by the Taylor series expansion approach using the exact differential equation and recursive calculation of high-order derivatives, and the functional iterative integration approach is re-implemented on the normal polynomial. This paper applies the two approaches to solve the strapdown attitude problem, using the attitude parameter of quaternion as a demonstration. Numerical results under the classical coning motion are reported to assess all derived attitude algorithms. It is revealed that in the low and middle relative conic frequency range all algorithms have the same order of accuracy, but in the range of high relative frequency the algorithm by the functional iterative integration approach performs the best in both accuracy and robustness if the Chebyshev polynomials and a larger number of gyroscope samples are to be used. The main conclusion applies to other attitude parameters as well.
Influence of Random Error of Temperature Sensors on the Quality of Temperature Compensation of Fog Bias by the Neural Network
Authors:   OKB TSP Scientific Production Limited Liability Company, Minsk, Belarus, Klimkovich B.V.
Published: January 2021

The formulas are obtained for estimating the «random walk» type noise of algorithmic compensation for the gyro bias. An example of estimating the statistical significance of the factors influencing the bias when calibrating a fiber-optic gyroscope in the operating temperature range and at different rates of their change is given. It is shown that the random error of temperature sensors can play a major role in the “random walk” noise of the algorithmic compensation for the gyro bias and exceed the gyro self noise. An example of obtaining a regression dependence of algorithmic compensation for gyro bias using a neural network with a multilayer perceptron is given. The factors influencing the choice of the time constant of the differentiating low-frequency temperature filter are considered. Experimental dependences of the random error of the bias algorithmic compensation on the value of the random error of temperature sensors are presented and the necessity of using temperature sensors with a minimum random error is shown.
Effect of Unequal Intensities of Counter-Propagating Waves on the Frequency Response of Laser Gyroscopes
Authors:   Polyus Research Institute named after M.F. Stel’makh, JSC, Moscow, Azarova V.V. , Golyaev Yu.D. ,   Polyus Research Institute named after M.F. Stel’makh, JSC, Moscow, Kuznetsov E.V. ,   Polyus Research Institute named after M.F. Stel’makh, JSC, Moscow
Published: January 2021

Frequency response of a laser gyroscope was studies by numerical modelling of a complete system of equations describing it. The calculation results are compared to the results of experimental measurements taken on a precision dynamic test bench. The frequency response was measured for a gyroscope based on a four-mirror ring laser with a non-planar contour, operating on He-Ne active mix at the wavelength of 632.8 nm. In the gyroscope under study, the sign-variable dither was implemented on the basis of Zeeman magnetooptical effect. The relationship between the measured and designed values of the frequency response distortions has been found. The relationship between the frequency response distortions in a laser gyroscope and inequality of field intensities of the counterpropagating waves (CPW) has been numerically calculated and confirmed by experiments. Based on the research results, the parameters of a ring laser can be optimized to improve the accuracy of measurements by means of laser gyroscopes.
Katsaus koronan vaikutuksista taiteen ja kulttuurin alojen toimintaedellytyksiin ja kulttuuripolitiikkaan Suomessa
Authors: Jakonen Olli , Luonila Mervi , Renko Vappu , Kanerva Anna
Published: January 2021

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Does sector matter?
Authors: Ruusuvirta Minna
Published: January 2021

YTM, KTM Minna Ruusuvirran kulttuuripolitiikan/yhteiskuntapolitiikan alaan kuuluvan väitöskirjan ”Does sector matter? Plural characteristics and logics in third sector festival organisations” tarkastustilaisuus pidettiin Jyväskylän yliopistossa 23. maaliskuuta 2019. Vastaväittäjänä toimi dosentti, FT, kaupunkitietopäällikkö, Timo Cantell (Helsingin kaupunki) ja kustoksena oli professori Miikka Pyykkönen (Jyväskylän yliopisto).
Nuorten yhteiskunnallinen osallistaminen kulttuuri- ja vapaa-ajan toiminnan kautta
Authors: Kumpulainen Kaisu , Husu Hanna-Mari
Published: January 2021

Nuorten osallistumisen ja osallisuuden lisäämisestä on tullut tärkeä yhteiskunnallinen tavoite, jota yritetään edistää erilaisten ohjelmien ja projektien kautta. Tarkastelemme artikkelissa osallistamista tutkimalla nuorille vuosina 2017­–2018 suunnattua kulttuuri- ja vapaa-ajan toimintaa Keski-Suomessa. Tutkimme, miten kulttuuriin liittyvällä toiminnalla pyritään edistämään nuorten laajempaa yhteiskunnallista osallistumista ja osallisuutta. Olemme haastatelleet 15 projekteissa työskentelevää tai vapaaehtoisena toimivaa henkilöä, ja analysoineet aineistoa osallistumisen kulttuurisen, sosiaalisen, taloudellisen ja poliittisen ulottuvuuden kautta. Tulosten mukaan nuorten osallistumista tutkittaessa on tärkeää nähdä kulttuuriin osallistuminen laajan määritelmän kautta, jotta voidaan tunnistaa myös ne osallistumisen tavat ja muodot, jotka jäävät helposti virallisten tarkastelujen ulkopuolelle. Nuorten osallistumisen ja osallisuuden rakentuminen on moninainen ja pienistä askelista rakentuva prosessi.
Protein Transfer v1
Authors: J Burgess Steven
Published: January 2021

This protocol is based on the assumption that TGX pre-cast gels have been used, the procedure is very similar for self-made gels, just that the running time is longer. Using the transfer packs is economically similar to wet-transfer using MeOH. Note: Clean the apparatus immediately after use with dH2O and dry. This prevents the build-up of salts and rust which impair performance. Literature: Full manual: https://www.bio-rad.com/webroot/web/pdf/lsr/literature/10020688.pdf Quick-start: https://www.bio-rad.com/webroot/web/pdf/lsr/literature/10016505D.pdf Transfer pack: https://www.bio-rad.com/webroot/web/pdf/lsr/literature/10019593D.pdf
Fluorescent Western Protocol v1
Authors: J Burgess Steven
Published: January 2021

Analysis of proteins using fluorescent immunoblot. Note: - The choice of secondary antibody depends on the choice of primary antibody, whether it is derived from a mouse (monoclonal) or a rabbit (polyclonal). - It is advisable to stick to the 800CW wavelength to avoid problems with chlorophyll autofluorescence encountered with the 680CW antibodies. Literature: https://www.licor.com/documents/fxc6evxvxbub4srkqy6i9yg46l7i0xz5
XPRIZE SANATA Protocol for Saliva LFIA Test v1
Authors: Thomas Mario , Sollen Jasmine , Ivanova Natalia , Feng Michelle , Fayek Reda , Abdilla Heidi , Lim Stephanie , Naaum Amanda , J Rumery Holly , Escobar Mario
Published: January 2021

This procedure outlines the protocol for testing for SARS-CoV-2 using a saliva sample collected from an individual. The purpose of this test is to detect low levels of SARS-CoV-2 antigen at a higher sensitivity. Precision Biomonitoring Inc. developed an ultra-rapid digital, disposable, highly-sensitive and inexpensive testing device used for screening purposes. The mobile app complementary to this medical device is connected through Bluetooth. Using this innovation, the user can be tested at point-of-care (POC) by a health care professional, and obtain qualitative results.
Features of the second half of pregnancy in women with labor abnormalities
Authors: Shokirova U. G. , Pakhomov S. P. , Ustyuzhina A. S. , Matrosova A. V.
Published: January 2021

Aim: conduct a systematic analysis of pregnancy development, investigate clinical and laboratory data affecting development of labor abnormalities in women residing in the Belgorod region. Materials and Methods. From 2014 to 2018, 484 women were examined and divided into 2 groups: main group consisted of those who had childbirth complicated with labor abnormalities (n = 344), whereas control group consisted of women lacking complications during delivery (n = 140). The following methods were used in the study: questionnaires, general clinical methods, biochemical blood tests in pregnant and postpartum women, populational statistics as well as methods of standard and multivariate statistics. Results. In the second half of pregnancy in women with labor abnormalities revealed higher rate of moderate preeclampsia (34.30 ± 2.56 % vs. 10.71 ± 2.61%; p < 0.05), polyhydramnios (11.34 ± 1.71 % vs. 5.71 ± 1.96 %; p < 0.05), chronic intrauterine hypoxia (29.6 ± 2.46 % vs. 12.86 ± 2.83 %; p < 0.05), chronic utero-placental insufficiency (60.47 ± 2.64 % vs. 20.00 ± 3.38 %; p < 0.05), sexually transmitted infections (3.78 ± 1.03 % vs. 0.71 ± 0.71 %; p < 0.05), acute respiratory viral infection (8.72 ± 1.52 % vs. 3.57 ± 1.57 %; p < 0.05) as well as a combination of several types of pathology (8.72 ± 1.52 % vs. 13.57 ± 2.89 %; p < 0.05). Laboratory parameters in women with labor abnormalities compared with control antepartum group were noted to have significantly decreased count of red blood cells (3.89 ± 0.38×1012/L vs. 3.99 ± 0.40×1012/L; p = 0.006), eosinophils (0.95 ± 0.69×109/L vs. 1.20 ± 0.67×109/L; p = 0.026) and platelets (226.29 ± 62.71×109/L vs. 245.44 ± 60.32×109/L; p = 0.0003). Blood biochemical parameters in women with labor abnormalities vs. control group were featured with significantly decreased level of bilirubin (6.76 ± 3.16 μmol/L vs. 9.88 ± 3.60 μmol/L; p < 0.05) and alanine aminotransferase (13.94 ± 10.08 U/L vs. 19.41 ± 14.40 U/L; p = 0.004). Analyzing coagulation parameters in the main group showed significantly reduced fibrinogen level (4.30 ± 1.00 g/L) compared with control group (4.71 ± 1.14 g/L; p < 0.05) as well as elevated international normalized ratio (1.07 ± 0.11 vs. 1.03 ± 0.10; p = 0.001). Conclusion. Our study data found that pregnant women with labor abnormalities had altered clinical and laboratory parameters observed as early as in the second half of gestation, which may be used to calculate an individual risk of such labor complication.
Magnesium-containing composition influencing morphological parameters and gelatinase B activity in endometrial tissues in experimental chronic endometrial inflammation
Authors: Rogova L. N. , Tikhaeva K. Yu. , Tkachenko L. V. , Shesternina N. V. , Povetkina V. N. , Staravoitov V. A. , Dyachkova S. Yu.
Published: January 2021

Aim: to assess an effect of medicinal magnesium-containing composition on gelatinase B expression intensity and morphological parameters of chronic experimental endometrial inflammation.

Materials and Methods. There were conducted experiments with 60 sexually mature female Wistar rats to determine an effect of medicinal magnesium-containing composition (contains magnesium chloride – a natural polymineral Bischofite) on gelatinase B activity in endometrial tissues (counting number of gelatinase-B-positive cells and intensity of gelatinase B expression), morphological parameters of cell infiltration, as well as amount of magnesium in red blood cell mass collected from the inferior vena cava and subclavian vein. All such parameters were assessed in experimental animals from 4 groups: group 1 – animals in baseline state, group 2 – control, group 3 – experimental chronic endometritis (CE), group 4 – experimental CE after treatment with medicinal magnesium-containing composition. Results. It was found that use of medicinal magnesium-containing composition increased amount of erythrocyte magnesium up to the baseline level and increased both number and expression intensity of stromal gelatinase B-positive cells. In addition, magnesium level in erythrocyte mass from the inferior vena cava was increased and accompanied with restored eosinophil-plasmacyte as well as significantly elevated macrophage-lymphocyte infiltration in endometrial tissues compared to CE animals lacking therapy. Conclusion. The results of this study allow us to conclude about importance of gelatinase B in pathogenesis of experimental chronic endometrial inflammation as well as an opportunity of regulating gelatinase B activity by applying medicinal magnesium containing drug in pathogenetic therapy of experimental CE.
Specifics of prescribing menopausal hormonal therapy in patients with the anamnestic endometriosis
Authors: Yarmolinskaya M. I. , Shalina M. A. , Seyidova C. I.
Published: January 2021

Administration of menopausal hormone therapy (MHT) in patients with genital endometriosis (GE) is a controversial issue requiring a patient-personalized approach. Current principles for MHT selection and prescription in patients with anamnestic endometriosis are presented, which are based on the guidelines of the International Menopause Society (IMS), The European Menopause and Andropause Society, local and foreign publications retrieved from electronic data bases PubMed, Cyberleninka. The data of our study on observing 724 patients with GE treated with diverse MHT types were presented and analyzed (428 women in perimenopausal period, 296 in postmenopausal period). Patients with endometriosis in perimenopausal and postmenopausal periods showed more prominent manifestations of climacteric and post-ovariectomy syndromes, as well as high risk of reduced bone mineral density (BMD) due to repeated surgery on the ovaries and preceding long-term “antiestrogen therapy”. Custom-compounded MHT based on components combinations, dosage and administration route provides a significantly improved quality of life for patients with endometriosis, prevents loss of BMD and reduces risk of cardiovascular diseases. Using low and ultra-low dose estrogen bioidentical to natural substances in this patient group minimizes a risk of disease recurrence.
Serous papillary cystadenofibroma combined with extended external genital endometriosis
Authors: Syrkashev E. M. , Solopova A. E. , Asaturova A. V.
Published: January 2021

Ovarian cystadenofibroma (CAF) is a rare ovarian tumor originating both from epithelial and stromal components being, however, classified as epithelial tumors. CAF prevalence among all ovarian tumors does not exceed more than 1.7 %. CAFs are commonly asymptomatic, in extremely rare cases of large tumor or ovarian torsion pain sensation may be noted. External genital endometriosis (EGE) is a chronic gynecological disorder that occurs in women of reproductive age and cause infertility and pelvic pain. EGE prevalence comprises around 10 % in women of reproductive age, 20–50 % in women with infertility, and almost 90 % in women with chronic pelvic pain. Magnetic resonance imaging (MRI) is method of choice in diagnostics of such pathology due to the high natural soft tissue contrast and functional techniques such as diffusion-weighted images (DWI) and dynamic contrast enhancement (DCE). Surgery planning, necessity for systemic therapy or follow-up directly depend on imaging and diagnostic laparoscopy results. Here we present a clinical case of rarely combined serous papillary CAF with extended EGE accompanied with consequences of intra-tumoral hemorrhage. Case study demonstrates main visualization characteristics that provide correct differential diagnosis and exclude malignancy transformation.
Genetic engineering approaches to the development of modern therapeutics
Authors: Bogomolova E. G. , Kopeykin P. M. , Tagaev A. A.
Published: January 2021

The classic approach to production of protein-based therapeutics is their isolation from natural sources. This approach was associated with a number of difficulties, such as collecting the primary material from natural sources, isolating and purifying the protein, and its standardizing. With the development of recombinant DNA technology, itbecame possible to obtain large quantities of protein preparations lacking any contaminations. Human insulin produced using recombinant DNA technology is the first commercial therapeutic obtained by this way. Due to the rapid development of genetic engineering technologies, a large number of proteins have been obtained inEscherichia colicells. In recent years, the approach for the development of drugs based on DNA molecules containing genes encoding therapeutic proteins has been developing more actively. Today, many scientists believe in the prospects of application of DNA vaccines. The ease of production, stability, the ability to mimic natural infections and elicit appropriate immune responses make this vaccine platform extremely attractive. Delivery and targeting of immunologically relevant cells are major tasks for maximizing the immunogenicity of DNA vaccines. Several different approaches that are currently being used to achieve this goal are discussed in this review. Pharmaceuticals based on nucleic acids have a number of undeniable advantages. The main options for prophylactic RNA vaccines, the methods used to deliver RNA to the cell, and methods for increasing the effectiveness of RNA vaccines are discussed. Usage of therapeutic drugs based on protein molecules and low molecular weight compounds is complicated by the fact that they cannot be targeted at a specific gene or its protein product, responsible for the occurrence of the disease. Action of nucleic acids can be directly directed to a particular DNA region in order to edit its nucleotide sequence. This method allows to correct a genetic defect, eliminating the cause of the disease. The principles of gene therapy and the successes achieved in this area are discussed. This review summarizes current achievements in the development of drugs based on recombinant proteins and nucleic acids.
Sas enterprise guide 6.1:
independent groups comparison for nominal data
Authors: Bunenkov N. S. , Bunenkova G. F. , Komok V. V. , Grinenko O. A. , Nemkov A S.
Published: January 2021

Objective:to develop algorithm of independent groups comparison for nominal data of prospective non-randomized clinical trial AMIRI CABG (ClinicalTrials.gov Identifier: NCT03050489) using SAS Enterprise Guide 6.1.
Materials and methods.Data collection was performed according to prospective non-randomized clinical trial AMIRI CABG in Pavlov First St. Petersburg State Medical University, Saint Petersburg, Russia between 2016-2019years with 336 patients. Patients were allocated into three groups of treatment. There is database which include following information: gender, myocardial infarction, stroke and postoperative bleeding. Comparison for nominal data (gender and incidence of myocardial infarction, stroke and bleeding) were calculated with SAS Enterprise Guide6.1 software with Chi-squared test and exact Fisher test.
Results.There was developed algorithm of two independent groups comparison for nominal data.
Conclusion.Presented algorithm of data analysis allows to compare independent groups for nominal data.
Determination of the trace element composition of human hair
Authors: Savinov S. S. , Riadchikova N. A. , Pikalova T. M. , Drobyshev A. I.
Published: January 2021

Hair is one of the promising non-invasive samples for monitoring the trace element composition of the human body. But it is necessary to take into account the individual and subpopulation characteristics of sample donors. Inthis work, we experimentally studied the features of the analysis of human hair samples for the determination of trace elements by arc atomic emission spectrometry using a dry residue after acid mineralization. Validation was carried out by comparative analysis by the method used, as well as by atomic emission spectrometry with inductively coupled plasma. It has been shown that the concentrations of Al, B, Ca, Cu, Fe, Mg, Mn, P, Pb, Zn in a set of 50samples from different donors obey the lognormal law, and therefore, the geometric mean (or median) is preferable as mean value. The content of Ca and Mg is higher in the female hair, while the content of Pb is higher in the male hair. Theconcentrations of Fe, Mn, and Pb are slightly higher in the hair of smokers than in non-smokers, but this difference is not statistically significant (probably due to the small sample size). Although the concentrations of several elements (including Mg, Mn, and P) differ in the hair of donors living in different regions of Russia, we failed to establish asignificant difference of this factor. Positive correlations were found between the contents of some elements, in particular, Mg/Ca, Al/Fe, Al/P, Cu/Fe, Cu/P, Fe/P, weaker relationships were found for Al/Cu, Ca/Mn, Cu/Pb, Mn/P.
Time Correction of Ocean-Bottom Seismometers Using Improved Ambient Noise Cross Correlation of Multicomponents and Dual-Frequency Bands
Authors: Tian Jinyu , Lin Jian , Zhang Fan , Xu Min , Zhang Yayun , Guo Laiyin , Zeng Xin
Published: January 2021

An effective approach was developed for identifying and correcting ocean-bottom seismometer (OBS) time errors through improving ambient noise cross-correlation function (NCCF) analysis and combination with other methods. Significant improvements were illustrated through analyzing data from a passive-source seismic experiment in the southwestern sub-basin of the South China Sea. A novel method was first developed that can effectively identify errors in the sampling frequency of the OBS instruments. The traditional NCCF method was then expanded by increasing the analyzed data spectrum from a single-frequency band to dual-frequency band pairs, thus doubling the number of available data points and substantially improving the time correction quality. For data with relatively low signal-to-noise ratios, the average time errors were reduced from the original average values of 60–80 ms by the conventional methods to <40  ms using the improved approaches. The new multistep procedure developed in this study has general applicability to analysis of other OBS experiments. The demonstrated significant improvements in the data quality are critical for advancing seismic tomography and other modern marine geophysical studies that require high accuracy in the OBS data.
Türk Sinemasında Gazeteci İmgesinin İnşası (1933-1965)
Authors: ÜNAL Barışkan
Published: January 2021

Araştırma, gazeteci karakterin ilk sunulduğu Cici Berber’den (Muhsin Ertuğrul, 1933) toplumsal gerçekçi akımı da içine alan Yeşilçam’ın yükselişinin ilk dönemine kadar, 1933-1965 yıllarında sinemada gazeteci imajı/imgesini ele almıştır. Toplumlarda gazeteciye yönelik güven-güvensizlik konusunda ikircikli yaklaşım bulunurken, bunda filmlerde inşa edilen ve on yıllarca pekiştirilen imajların da etkisi vardır. Özellikle de ardılları için ilham ve model oluşturduğundan ilk dönemlerde kurulan ve basmakalıplaştırılan imajların tespiti kamunun süregelen bakışını ve gazeteci temsilinin sinemada kökenini anlamada önem taşımaktadır. Bu noktada Hollywood sinemasına dair birçok araştırma bulunurken, Türk sinemasında genel anlamda çok sınırlı, ilk dönemleri kapsayansa hiç araştırma olmadığı görülmüştür. Bu bağlamda çalışmada, gazetecinin ana veya etkin yan karakter olduğu 28 film, Campbell ve Vogler’in Kahraman Yolculuğu ile Amerikan filmlerinde gazetecilerin yolculuk şeması temelinde ve sinema genelinde gazeteci karakterine dair ortaya konan sınıflandırmalar, arketipler ve stereotipler üzerinden belirlenen parametrelerle analiz edilmiştir. Araştırma sonucunda, Türk filmlerinde gazetecinin yolculuğunda anlatının kendi özgün yapısını kurduğu görülmüştür. Filmlerde gazeteci kategorilerinden hem Hakikat Araştırmacısı hem Manşet Gazetecisi hem de ikisinin melez inşasına rastlanmış, klasik Yeşilçam’da iki tipleme de kahraman arketipine yerleştirilirken, toplumsal gerçekçilik filmlerinde ilkinin özgür basın temsilcisi ve kahraman, ikincisinin kötü adam ve güdümlü gazeteci olarak inşa edildiği tespit edilmiştir. Bunun yanında, Cici Berber’den itibaren gazetecinin haberi elde etmek için Kılık Değiştiren arketipinde, Yılmaz Ali’den itibaren de hafiye olarak sunumuna rastlanmıştır. Sinemada genelindeki gazeteci stereotiplerinin bir kısmı Türk filmlerinde de belirirken, özgün stereotip inşaları da bulunmuştur. Tüm bu temsillerin özünde basının gücüne dair mitlerin inşası dikkati çekmiştir.
Gloria Velásquez’s Roosevelt High School series: towards quality multicultural literature through rainbow coalitions
Authors: Fernández Rodríguez Carolina
Published: January 2021

The goal of this paper is to study several YA novels by Chicana writer Gloria Velásquez, the Roosevelt High School series (1994-2018), as an educating tool within the framework of multicultural education. The analysis takes into account Velásquez’s choice of problematic situations (related to racism, sexism, or homophobic harassment, among others) and the solutions her novels propose, which include both individual responses and community-organized measures. Special attention is given to the criticism according to which Velásquez’s Latinx and multi-ethnic characters are steeped in stereotypes, which would cancel the books’ potential capacity to inspire social change. In contrast with this negative vision, this paper proves that Velásquez’s series offers empowering role models for teen Latinxs of various ethnic backgrounds and effectively calls for the neutralization of race, class and gender stereotypes, thus contributing to the implementation of Jesse Jackson’s 1984 proposal that ethnic minorities should form a “rainbow coalition”.
An Anthropological Study of Hospitality: The Innkeeper and the Guest
Authors:   Universidad de Palermo, Buenos Aires, Argentina, Korstanje Maximiliano E.
Published: January 2021

In an ever-changing world which characterizes by the decline of hospitality, the anthropological insight is essentially vital to envisage the future of Western civilization. Amitai Touval adventures to reach a much deeper and better understanding of hospitality; en his recently-published book, [An anthropological study of Hospitality: the innkeeper and the guest], which is formed by two chapters, he offers a more than interesting argument. The first chapter, which entitles The Inkeeper, speaks us of his experiences in Eastern Germany. Rather, the second one goes through the evolution of hospitality in the digital media as well as virtual world. In so far as technology monopolizes hospitality, the guest-host relations are more impersonal. The author discusses critically the limitations of Airbnb.
Theoretical Reflections on Public Governance and Tourist Governance
Authors:   Universidade de São Paulo, São Paulo, Brasil, Kalaoum Fausi , Trigo Luiz Gonzaga Godoi ,   Universidade de São Paulo, São Paulo, Brasil
Published: January 2021

The changes due to the social and political aspect around the world, which began around the 70's, contributed to rethink a new model [or models] of public management. This structural change in the Brazilian State, which some authors define as Governance, is the starting point for this work. Thus, the objective of this work is to stimulate and contribute to a theoretical construction of Governance and its application to the touristic governance. With a qualitative approach, the bibliographic research was used as a technique in engendering this work, focusing on the readings on Public Governance, New Public Management and Tourism Governance. Among the results achieved are the identification of divergences or lack of precision of the concept of governance and the identification of common elements in the literature that may help a better understanding of this construct.
Numerical Study of Heat Transfer and Exergy Analysis of Shell and Double Tube Heat Exchanger
Authors: Abdulrahman Ruslan S. , Ibrahim Farah A. , Faisel Safaa H.
Published: January 2021

The heat exchanger (HX) plays a key role for several industries, to reduce the energy consumption by rising heat transfer rate through heat exchanger. In this study, numerical simulation of shell and double tube heat exchanger without and with baffles is analyzed to evaluate the heat transfer and exergy analysis. A numerical simulation of 3D model with turbulent flow at the range (4000-12000) is performed with commercial computational fluid dynamics (CFD) software ANSYS (Fluent). The circular vents baffles model is used at the side of the shell. The simulation results show that the circular vents on the baffles of the heat exchanger have a significant impact on thermal- hydraulic performance and exergy analysis. Also, the results show that the heat exchanger effectiveness with baffles increases by 17% at high Reynolds number comparing with heat exchanger without baffles. Besides, the highest value of exergy loss reached to 42W with baffles presence. Finally, it is concluded that the heat exchanger with baffles gives better hydraulic and thermal performance than that of heat exchanger without baffles.
Perjumpaan school: a new model of character learning in plural community
Authors: Quddus Abdul
Published: January 2021

Family, education school and community are strategic educational institutions in shaping the character of the nation that upholds integrity, honesty and commitment, but the fact is that these various institutions have not yet fully embodied the characters they aspire. Many character problems and abnormal social relations are experienced by learners in Indonesian educational institutions. Various models of character internalization emerged and developed to respond to this fact, including the Integrated Islamic School (SIT) education model, Living Values Education (LVE), The ESQ Way 165 and the Perjumpaan School Community. This article aims to analyze the character learning model developed by Perjumpaan School. This study uses qualitative research with descriptive analysis as a model for data analysis. This study found that Perjumpaan School has developed a new model in character learning. Perjumpaan School emphasized mental state management and languaging. Mental state is related to positive feelings or emotions while languaging is the use of norms inherent in language action. Positivity mental state and languaging in every encounter are efforts to normalize social relations that are open, tolerant and mutually acceptable to plural society.