bluuebunny/crossref_metadata_2025 huggingface dataset:
Facing a Second Wave from a Regional View: Spatial Patterns of COVID-19 as a Key Determinant for Public Health and Geoprevention Plans
Authors: Cos Olga De , Castillo Valentín , Cantarero David
Published: November 2020

Several studies on spatial patterns of COVID-19 show huge differences depending on the country or region under study, although there is some agreement that socioeconomic factors affect these phenomena. The aim of this paper is to increase the knowledge of the socio-spatial behavior of coronavirus and implementing a geospatial methodology and digital system called SITAR (Fast Action Territorial Information System, by its Spanish acronym). We analyze as a study case a region of Spain called Cantabria, geocoding a daily series of microdata coronavirus records provided by the health authorities (Government of Cantabria—Spain) with the permission of Medicines Ethics Committee from Cantabria (CEIm, June 2020). Geocoding allows us to provide a new point layer based on the microdata table that includes cases with a positive result in a COVID-19 test. Regarding general methodology, our research is based on Geographical Information Technologies using Environmental Systems Research Institute (ESRI) Technologies. This tool is a global reference for spatial COVID-19 research, probably due to the world-renowned COVID-19 dashboard implemented by the Johns Hopkins University team. In our analysis, we found that the spatial distribution of COVID-19 in urban locations presents a not random distribution with clustered patterns and density matters in the spread of the COVID-19 pandemic. As a result, large metropolitan areas or districts with a higher number of persons tightly linked together through economic, social, and commuting relationships are the most vulnerable to pandemic outbreaks, particularly in our case study. Furthermore, public health and geoprevention plans should avoid the idea of economic or territorial stigmatizations. We hold the idea that SITAR in particular and Geographic Information Technologies in general contribute to strategic spatial information and relevant results with a necessary multi-scalar perspective to control the pandemic.
Hearing the Voices of Wingless Angels: A Critical Content Analysis of Nurses’ COVID-19 Experiences
Authors: Arasli Huseyin , Furunes Trude , Jafari Kaveh , Saydam Mehmet Bahri , Degirmencioglu Zehra
Published: November 2020

The world has been affected by an outbreak of the novel coronavirus (COVID-19). Health care workers are among those most at risk of contracting the virus. In the fight against the coronavirus, nurses play a critical role. Still, most social media platforms demonstrate that nurses fear that their health is not being prioritized. The purpose of this study is to investigate nurses’ experiences through analyzing the main themes shared on Instagram by nurses during the COVID-19 pandemic. In contrast with highly structured research, the current paper highlights nurses’ natural language use in describing their experiences during the first months of the outbreak in their workplace. Instagram captions were utilized as a data source. Leximancer was utilized for the content analysis of nurses’ narratives towards their coronavirus experience. We sought to accomplish three research objectives: the first was to identify the main themes in the descriptions of nurses’ experiences shared via their social media, specifically Instagram; then, to determine the relationships among concepts, and finally, to give useful implications based on the findings. The current study uses a qualitative (i.e., narratives) approach to analyze the main components of the nurses’ experiences during the pandemic. The Leximancer software analysis revealed nine major textual themes and the relationships among these themes. In order of the relative importance, the themes were “patients”, “coronavirus”, “exhaustion”, “family”, “hospital”, “personal protective equipment” (PPE), “shift”, “fear”, and “uncertainty”. The results offer practical implications based on the social media information regarding nurses’ overall experiences.
Temporal and Spatial Heterogeneity of Soil Erosion and a Quantitative Analysis of its Determinants in the Three Gorges Reservoir Area, China
Authors: Chu Lin , Sun Tiancheng , Wang Tianwei , Li Zhaoxia , Cai Chongfa
Published: November 2020

As the most typical ecologically fragile area in South China, the Three Gorges Reservoir Area (TGRA) suffers from water and soil loss, which has threatened the local ecological environment. Understanding the spatial heterogeneity of soil erosion and exploring its determinants are of great significance in preventing soil erosion and maintaining ecological sustainability in the TGRA. This study investigates the spatial heterogeneity of soil erosion and quantitatively identifies the determinants in the TGRA based on the Chinese Soil Loss Equation (CSLE) and geographical detector method. This study concluded that the soil erosion status generally improved from 1990 to 2015, showing an increasing trend from 1990 to 2000 and a decreasing trend from 2000 to 2010. Slope, land use, and vegetation coverage were the dominant individual factors affecting soil erosion in the TGRA. For the interaction factor, the combinations of land-use type and slope and vegetation coverage and slope were the key determinants, explaining 68.7% and 63.1% of the spatial heterogeneity of soil erosion in the TGRA from 1990 to 2015, respectively. Moderate and higher levels of soil erosion occurred in areas where the slope was greater than 25°. Among the land-use types, dry land and bare land were prone to soil erosion. These findings reveal that land-use type and vegetation coverage should be considered for the effective prevention of soil erosion, and cultivation on sloped farmland should be prohibited, especially on slopes higher than 25° in the TGRA.
First Report of Canine Infection by Leishmania (Viannia) guyanensis in the Brazilian Amazon
Authors: Santos Francisco J. A. , Nascimento Luciana C. S. , Silva Wellington B. , Oliveira Luciana P. , Santos Walter S. , Aguiar Délia C. F. , Garcez Lourdes M.
Published: November 2020

The American cutaneous (CL) and visceral leishmaniasis (VL) are zooanthroponoses transmitted by sand flies. Brazil records thousands of human leishmaniasis cases annually. Dogs are reservoirs of Leishmania infantum, which causes VL, but their role in the transmission cycle of CL is debatable. Wild mammals are considered reservoirs of the aetiological agents of CL (Leishmania spp.). Objective: To describe the aetiology of leishmaniasis in dogs in an endemic area for CL and VL in the Amazon, Brazil. Methods: Clinical evaluation and blood collection of 40 dogs from the villages Ubim (20) and Socorro (20), city of Tomé-Açu, state of Pará, were carried out. The DNA extracted from the blood was used for PCR with Leishmania-specific primers targeting the hsp70-234 gene sequence. Products were sequenced (ABI3500XL), and the sequences were aligned, edited (BioEdit), and analyzed (Blastn). Results: Of the 34 amplified samples, 21 were sequenced, namely Leishmania infantum (12), L. guyanensis (5), L. braziliensis (3), and Leishmania sp. (01). Conclusion: Given the diversity of circulating pathogens, elucidation of the role of the dog in the Leishmania spp. cycle in Amazonian villages is imperative to the surveillance of CL in the region. We present the first report in Brazil, confirmed by sequencing, of canine infection by L. guyanensis, a species highly resistant to treatment in humans, with the drug of first choice (Glucantime®).
Sleep Duration, Sleep Quality and Physical Activity, but Not Sedentary Behaviour, Are Associated with Positive Mental Health in a Multi-Ethnic Asian Population: A Cross-Sectional Evaluation
Authors: Vaingankar Janhavi Ajit , Müller-Riemenschneider Falk , Chu Anne Hin Yee , Subramaniam Mythily , Tan Linda Wei Lin , Chong Siow Ann , van Dam Rob M.
Published: November 2020

Background: We assessed the associations of sleep, physical activity and sedentary behaviour with positive mental health (PMH) in the multi-ethnic population of Singapore. Methods: The Singapore Health 2 study is a nationally representative cross-sectional survey among residents aged 18–79 years. A PMH instrument was administered to 1925 participants to obtain total PMH and six sub-component scores. Self-rated sleep duration, sleep quality, sedentary behaviour and physical activity were assessed. Multivariable linear regression analyses were conducted. Results: The mean age of the participants was 40.1 (SD 14.3) years. Sleep duration (≥8 h/night: β = 0.17,95% CI: 0.02–0.32; 7–< 8 h/night: β = 0.17,95% CI: 0.03–0.30 versus <6 h/night, p = 0.002), sleep quality (very good: β = 0.45,95% CI: 0.29–0.60; fairly good: β = 0.20,95% CI: 0.06–0.33 versus very/fairly bad; ptrend < 0.001) and physical activity (high: β = 0.19,95% CI: 0.05–0.32; moderate: β = 0.15, 95% CI: 0.03–0.27 versus low; ptrend < 0.001) were directly associated with total PMH. Sedentary behaviour was not significantly associated with PMH. Sleep duration, sleep quality and physical activity were directly associated with the PMH sub-components ‘emotional support’ and ‘personal growth and autonomy’. Conclusions: Duration and quality of sleep and physical activity were directly associated with PMH in an urban Asian population. These findings support incorporating sleep and physical activity interventions to improve population mental health.
Children’s Internet Use Profiles in Relation to Behavioral Problems in Lithuania, Latvia, and Taiwan
Authors: Pakalniškienė Vilmantė , Jusienė Roma , Sebre Sandra B. , Chun-Li Wu Jennifer , Laurinaitytė Ilona
Published: November 2020

This study explored the profiles of elementary-school-aged children’s Internet use in relation to their emotional and behavioral problems. Participating in this cross-sectional study were 877 child–parent dyads from Latvia, Lithuania, and Taiwan. Children (8–10 years old) provided information on three variables: the amount of time they spent online, frequency of online activities, and knowledge of how to do things online. Latent profile analysis including these three variables provided a four-class solution for child Internet use. A comparison between Latvia, Lithuania, and Taiwan on the percentage of the sample distribution in each class showed that there was no difference between sites for the high class (high ratings on all three variables). The largest differences were for the low and average classes (low and average ratings on all three variables, namely, time online, frequency, and knowledge): the Lithuanian and Taiwanese samples were similar in that a higher percentage of each sample was in the low class, whereas the Latvian sample had children equally distributed between the low class and the average class. Analysis of the data from the entire sample for differences in parent-reported child behavioral difficulties suggested that children in the high class had an elevated level of behavioral problems and compulsive Internet use.
International Study of Movement Behaviors in the Early Years (SUNRISE): Results from SUNRISE Sweden’s Pilot and COVID-19 Study
Authors: Delisle Nyström Christine , Alexandrou Christina , Henström Maria , Nilsson Ellinor , Okely Anthony D. , Wehbe El Masri Serina , Löf Marie
Published: November 2020

The International Study of Movement Behaviors in the Early Years (SUNRISE) was initiated in response to the 2019 WHO guidelines for physical activity, sedentary behavior, and sleep in children aged 0–5 years. This Swedish pilot study aimed to: (i) assess the proportion of preschoolers meeting the guidelines, (ii) evaluate the feasibility of the methods for the SUNRISE study, and (iii) assess how movement behaviors have been affected in preschoolers during the COVID-19 pandemic. Physical activity and sleep (waist-worn ActiGraph); screen time and movement behaviors (parental questionnaire); motor skills (Ages and Stages Questionnaire); and executive functions (3 iPad games) were assessed in 100 Swedish preschoolers (n = 58 boys). There were 19.4% of preschoolers (n = 14) who met the WHO guidelines. The motor skill and executive function assessments were feasible; however, 20% refused to wear the ActiGraph overnight. Additionally, during the pandemic Swedish children’s physical activity, time spent outside on weekdays and weekend days, and screen time significantly increased (+53; +124; +68; +30min/day, respectively, all p-values ≤ 0.001). Methods for the SUNRISE study were feasible in a Swedish context; however, considerations to switch to a wrist-worn accelerometer should be made. Furthermore, children’s physical activity increased during the pandemic, which is likely due to how the rules/restrictions were implemented in Sweden.
Effect of Using an 8-Figure Shoulder Brace on Posture and Muscle Activities during the Performance of Dental Hygiene Procedures
Authors: Yoon Tae-Lim , Min Ji-Hyun , Kim Han-Na
Published: November 2020

The incidence of work-related musculoskeletal disorders (MSDs) among dental workers has been increasing. Many ergonomic devices and accessories have been introduced. The aim of this study was to investigate the effects of an 8-figure shoulder brace on posture-related muscle activities in dental hygiene practitioners during scaling procedures. In this study, 33 participants (age: 21.9 ± 2.1 years, height: 162.0 ± 6.0 cm, weight: 55.8 ± 9.0 kg, body mass index: 21.2 ± 2.4 kg/m2) performed the scaling procedure with and without the 8-figure shoulder brace in a randomized order. The normalized electromyography activity in the amplitude probability distribution function and joint angles (cervical, thoracic, lumbar, and shoulder joints) were simultaneously recorded during scaling. A paired t test was used to compare the differences in muscle kinematics, with the alpha level set at 0.05. The dental hygienists who wore the 8-figure shoulder brace during scaling showed thoracic and lumbar extension, improved sitting postures, and reduced shoulder joint abduction. However, we also observed an unintended increase in internal rotation. Use of the 8-figure shoulder brace could prevent work-related MSDs in lumbar and thoracic regions by reducing the effort exerted by the upper trapezius and deltoid muscles, despite the increased muscular effort of the cervical erector spinae.
Sustainable Value Co-Creation in the Virtual Community: How Diversified Co-Creation Experience Affects Co-Creation Intention
Authors: Chen Yi-Wen
Published: November 2020

The popularization of digital infrastructure has enabled the rise of the online game industry. Instead of targeting entertainment-oriented technology and services, which are the focus of most relevant studies, in the present study, we review the literature from the perspective of considering players of online games as both consumers of entertainment and co-creators of value. The three major antecedents of the theory of planned behavior, namely personal attitude toward co-creation, subjective norms and perceived behavioral control, were modified to explore the relevant constructs. Specifically, the diversity of co-creation experience was used to predict co-creation intention. The proposed model was empirically evaluated through the structural equation modeling of survey data collected from 321 World of Warcraft (WoW) players. As hypothesized, the diversified co-creation experience positively affected the antecedents. The findings provide implications on how to increase players’ participation in co-creation to achieve sustainable mutual benefits.
Sex Differences in Time-Domain and Frequency-Domain Heart Rate Variability Measures of Fatigued Drivers
Authors: Zeng Chao , Wang Wenjun , Chen Chaoyang , Zhang Chaofei , Cheng Bo
Published: November 2020

The effects of fatigue on a driver’s autonomic nervous system (ANS) were investigated through heart rate variability (HRV) measures considering the difference of sex. Electrocardiogram (ECG) data from 18 drivers were recorded during a simulator-based driving experiment. Thirteen short-term HRV measures were extracted through time-domain and frequency-domain methods. First, differences in HRV measures related to mental state (alert or fatigued) were analyzed in all subjects. Then, sex-specific changes between alert and fatigued states were investigated. Finally, sex differences between alert and fatigued states were compared. For all subjects, ten measures showed significant differences (Mann-Whitney U test, p < 0.01) between different mental states. In male and female drivers, eight and four measures, respectively, showed significant differences between different mental states. Six measures showed significant differences between males and females in an alert state, while ten measures showed significant sex differences in a fatigued state. In conclusion, fatigue impacts drivers’ ANS activity, and this impact differs by sex; more differences exist between male and female drivers’ ANS activity in a fatigued state than in an alert state.
Clinical Risk and Overall Survival in Patients with Diabetes Mellitus, Hyperglycemia and Glioblastoma Multiforme. A Review of the Current Literature
Authors: Montemurro Nicola , Perrini Paolo , Rapone Biagio
Published: November 2020

The relationship between type 2 diabetes mellitus (DM2) and hyperglycemia with cancer patients remains controversial also in the setting of patients with glioblastoma multiforme (GBM), the most common and aggressive form of astrocytoma with a short overall survival (OS) and poor prognosis. A systematic search of two databases was performed for studies published up to 19 August 2020, reporting the OS of patients with DM2 or high blood sugar level and GBM and the clinical risk of diabetic patients for development of GBM. According to PRISMA guidelines, we included a total of 20 papers reporting clinical data of patients with GBM and diabetes and/or hyperglycemia. The aim of this review was to investigate the effect of DM2, hyperglycemia and metformin on OS of patients with GBM. In addition, we evaluated the effect of these factors on the risk of development of GBM. This review supports accumulating evidence that hyperglycemia, rather than DM2, and elevated BMI are independent risk factors for poor outcome and shorter OS in patients with GBM. GBM patients with normal weight compared to obese, and diabetic patients on metformin compared to other therapies, seems to have a longer OS. Further studies are needed to understand better these associations.
Linkage of Maternal Caregiver Smoking Behaviors on Environmental and Clinical Outcomes of Children with Asthma: A Post-Hoc Analysis of a Financial Incentive Trial Targeting Reduction in Pediatric Tobacco Smoke Exposures
Authors: Jassal Mandeep S. , Lewis-Land Cassia , Thompson Richard E. , Butz Arlene
Published: November 2020

(1) Background: Monthly variability in smoking behaviors in caregivers of pediatric asthmatics yields questions of how much and when does smoking reduction result in improved environmental and clinical outcomes. (2) Methods: Post hoc analysis of data from a 6 month pilot randomized-control trial occurring from May 2017 to May 2018 in Baltimore City (MD, USA). The initial trial’s primary intervention explored the utility of financial incentives in modifying caregiver smoking behaviors. Post hoc analyses examined all dyads independent of the initial trial’s randomization status. All caregivers received pediatric tobacco smoke harm reduction education, in addition to monthly encouragement to access the state tobacco quitline for individual phone-based counseling and nicotine replacement therapy. Maternal caregivers who were active cigarette smokers and their linked asthmatic child (aged 2–12 years) were grouped into two classifications (“high” versus “low”) based on the child and caregiver’s cotinine levels. A “low” cotinine level was designated by at least a 25% reduction in cotinine levels during 3 months of the trial period; achieving ≤2 months of low cotinine levels defaulted to the “high” category. Twenty-seven dyads (caregivers and children) (total n = 54) were assigned to the “high” category, and eighteen dyads (caregivers and children) (total n = 36) were allocated to the “low” category. The primary outcome measure was the correlation of caregiver cotinine levels with pediatric cotinine values. Secondary outcomes included asthma control, in addition to caregiver anxiety and depression. (3) Results: Caregivers with 3 months of ≥25% decrease in cotinine levels had a significantly greater mean change in child cotinine levels (p = 0.018). “Low” caregiver cotinine levels did not significantly improve pediatric asthma control (OR 2.12 (95% CI: 0.62–7.25)). Caregiver anxiety and depression outcomes, measured by Patient Health Questionnaire (PHQ)-4 scores, was not significantly different based on cotinine categorization (p = 0.079); (4) Conclusion: Reduced pediatric cotinine levels were seen in caregivers who reduced their smoking for at least 3 months, but clinical outcome measures remained unchanged.
Longitudinal Growth Curve Trajectories of Family Dynamics after Pediatric Traumatic Brain Injury in Mexico
Authors: McKee Grace B. , Olabarrieta-Landa Laiene , Pérez-Delgadillo Paula K. , Valdivia-Tangarife Ricardo , Villaseñor-Cabrera Teresita , Ramos-Usuga Daniela , Perrin Paul B. , Arango-Lasprilla Juan Carlos
Published: November 2020

Pediatric traumatic brain injury (TBI) represents a serious public health concern. Family members are often caregivers for children with TBI, which can result in a significant strain on familial relationships. Research is needed to examine aspects of family functioning in the context of recovery post-TBI, especially in Latin America, where cultural norms may reinforce caregiving by family members, but where resources for these caregivers may be scarce. This study examined caregiver-reported family satisfaction, communication, cohesion, and flexibility at three time points in the year post-injury for 46 families of a child with TBI in comparison to healthy control families. Families experiencing pediatric TBI were recruited from a large hospital in Guadalajara, Mexico, while healthy controls were recruited from a local educational center. Results from multilevel growth curve models demonstrated that caregivers of children with a TBI reported significantly worse family functioning than controls at each assessment. Families experiencing pediatric TBI were unable to attain the level of functioning of controls during the time span studied, suggesting that these families are likely to experience long-term disruptions in family functioning. The current study highlights the need for family-level intervention programs to target functioning for families affected by pediatric TBI who are at risk for difficulties within a rehabilitation context.
Perceived Value of Electronic Medical Records in Community Health Services: A National Cross-Sectional Survey of Primary Care Workers in Mainland China
Authors: Xia Zining , Gao WenJuan , Wei Xuejuan , Peng Yingchun , Ran Hongjun , Wu Hao , Liu Chaojie
Published: November 2020

Objective: To evaluate the degree to which electronic medical records (EMRs) were used in primary care and the value of EMRs as perceived by primary care workers in China. Methods: A cross-sectional survey was conducted on 2719 physicians (n = 2213) and nurses (n = 506) selected from 462 community health centres across all regions of mainland China except for Tibet. Regional differences in the responses regarding the functionality of existing EMR systems and the perceived value of EMRs were examined using Chi-square tests and ordinal regression analyses. Results: Less than 59% of the community health centres had adopted EMRs. More than 89% of the respondents believed that it was necessary to adopt EMRs in primary care. Of the existing EMR systems, 50% had access to telehealth support for laboratory, imaging or patient consultation services. Only 38.4% captured data that met all task needs and 35.4% supported referral arrangements. “Management of chronic conditions” was voted (66%) as the top preferred feature of EMRs. Higher levels of recognition of the value of EMRs were found in the relatively more developed eastern region compared with their counterparts in other regions. Conclusions: Rapid EMR adoption in primary care is evident in mainland China. The low level of functionality in data acquisition and referral arrangements runs counter to the requirements for “management of chronic conditions”, the most preferred feature of EMRs in primary care. Regional disparities in the realised value of EMRs in primary care deserve policy attention.
Creating Short-Term Volume Flexibility in Healthcare Capacity Management
Authors: Fagefors Carina , Lantz Björn , Rosén Peter
Published: November 2020

It is well-known that unpredictable variations in supply and demand of capacity in healthcare systems create the need for flexibility. The main tools used to create short-term volume flexibility in the healthcare system include overtime, temporary staff from internal calling lists, moving staff across units, internal staffing pools, external staffing agencies, queuing patients, and purchasing care from external providers. We study the creation of short-term volume flexibility in healthcare systems to manage short-term capacity losses and demand fluctuations. A questionnaire was developed and distributed among healthcare managers in the Region Västra Götaland healthcare system. Respondents were asked to what extent they used each tool to create short-term flexibility in capacity. Data were analyzed using multiple regression analysis. Several significant tendencies were found, including that acute units use overtime and internal staffing pools to a larger extent, and queuing patients and external providers to a lesser extent than planned units. The prerequisites and required managerial approaches used to efficiently manage aggregate capacity in the system differ substantially between different parts of the system. These differences must be addressed when, for example, capacity pools are considered. These results serve as a stepping stone towards a more thorough understanding of efficient capacity management in healthcare systems.
Patterns of Service Provision in Older People’s Mental Health Care in Australia
Authors: Tabatabaei-Jafari Hossein , Salinas-Perez Jose A. , Furst Mary Anne , Bagheri Nasser , Mendoza John , Burke David , McGeorge Peter , Salvador-Carulla Luis
Published: November 2020

Australia has a population of around 4 million people aged 65 years and over, many of whom are at risk of developing cognitive decline, mental illness, and/or psychological problems associated with physical illnesses. The aim of this study was to describe the pattern of specialised mental healthcare provision (availability, placement capacity, balance of care and diversity) for this age group in urban and rural health districts in Australia. The Description and Evaluation of Services and DirectoriEs for Long Term Care (DESDE-LTC) tool was used in nine urban and two rural health districts of the thirty-one Primary Health Networks across Australia. For the most part service provision was limited to hospital and outpatient care across all study areas. The latter was mainly restricted to health-related outpatient care, and there was a relative lack of social outpatient care. While both acute and non-acute hospital care were available in urban areas, in rural areas hospital care was limited to acute care. Limited access to comprehensive mental health care, and the uniformity in provision across areas in spite of differences in demographic, socioeconomic and health characteristics raises issues of equity in regard to psychogeriatric care in this country. Comparing patterns of mental health service provision across the age span using the same classification method allows for a better understanding of care provision and gap analysis for evidence-informed policy.
The Association between Material Deprivation and Avoidable Mortality in Lisbon, Portugal
Authors: Costa Claudia , Freitas Angela , Almendra Ricardo , Santana Paula
Published: November 2020

There is considerable evidence pointing to the existence of a socioeconomic gradient in mortality, which tends to be steeper in urban areas. Similar to other European cities, Lisbon is far from homogeneous since considerable geographical inequalities exist between the more advantaged and the more deprived neighborhoods. The main goals of this study are to describe the geographical pattern of premature deaths (before 65 years old), avoidable deaths (preventable and amenable to healthcare) and cause-specific mortality (HIV/AIDS and suicide) in Lisbon, at the lower administrative level (civil parish, in Portuguese: Freguesia), and analyze the statistical association between mortality risk and deprivation, before (1999–2003) and during the economic crisis (2008–2012). Smoothed Standardized Mortality Ratios (sSMR) and Relative Risk (RR) with 95% credible intervals were calculated to identify the association between mortality and deprivation. The analysis of the geographical distribution of cause-specific mortality reveals that civil parishes with high sSMR in the first period continued to present higher mortality rates in the second. Moreover, a significant statistical association was found between all the causes of death and deprivation, except suicide. These findings contribute to understanding how social conditions influence health outcomes and can offer insights about potential policy directions for local government.
Psychological Distress of University Workers during COVID-19 Pandemic in Brazil
Authors: Serralta Fernanda Barcellos , Zibetti Murilo Ricardo , Evans Chris
Published: November 2020

The study aimed to explore mental distress during COVID-19 quarantine in a sample of university workers in Brazil. The survey included sets of questions about demographics, health, and support, an open question about major concerns, and the Clinical Outcome Routine Evaluation (CORE-OM), a measure of mental distress. A total of 407 professionals, mean age 40, SD 11.2, fulfilling social distancing (99%) participated in the study. Participants were mostly female (67.8%) and married (64.8%). Using the Consensual Qualitative Research process for simple qualitative data (CQR-M), the main areas of concern were grouped into six domains, as follows: work, health, isolation, personal life and routine, social environment, and future. Many responses were multiple. They form categories indicating specific concerns within these domains. Quantitative data were analyzed by identifying the simple effects of potential predictors of mental distress. The results indicated medium effects of help with household chores (η2 = 0.06, 95% confidence interval (CI) (0.022–0.095)), psychiatric treatment (η2 = 0.06, CI (0.030–0.110)), age (η2 = 0.12, CI (0.070–0.170)), and physical exercise (η2 = 0.12, CI (0.079–0.180)). Having someone available to listen was the only variable with a large effect associated with reduced mental suffering (η2 = 0.18; CI (0.118–0.227)). Psychological experiences of the pandemic are multifaceted and complex. Thus, substantially larger surveys, with both quantitative and qualitative components, are needed.
An Update on Physical Activity Research among Children in Hong Kong: A Scoping Review
Authors: Zhang Chun-Qing , Chung Pak-Kwong , Cheng Shi-Shi , Yeung Vincent Wing-Chun , Zhang Ru , Liu Sam , Rhodes Ryan E.
Published: November 2020

Similar to their Western counterparts, children in Hong Kong generally fail to reach the recommended levels of physical activity (PA). As an ultra-dense metropolis, Hong Kong is different from most Western cities. It is therefore important to update and appraise previous PA research in order to inform future PA promotion for Hong Kong children. Using a scoping review, the current study aimed to evaluate PA research among preschool and school-aged children in Hong Kong aged 3–12 years old who are at a critical development stage. Literature was searched from four English databases: Medline via EBSCOhost, SPORTDiscus, ERIC and PsycINFO via ProQuest; and three Chinese databases: CNKI, CQVIP and WAN-FANG. PA research among Hong Kong children published from 1 January 1997 to the searching date, 31 March 2020 was included. A total of 63 studies were identified, with the majority of studies focused on school-aged children as compared to preschoolers, adopted a cross-sectional design, using self-reported PA measures, and with small to medium sample sizes. We classified eligible studies into five main categories: (a) Health benefits of PA (k = 12). Consistent evidence on the health benefits of skeletal and cardiovascular capacity, quality of life, cognitive function, and sleep quality was revealed. However, inconsistent evidence was found on the benefits of weight-related indicators and academic performance. (b) Patterns of PA (k = 12). There is a general pattern of low levels of PA among Hong Kong children, in particular girls and children with special educational needs. (c) Measures of PA and related constructs (k = 11). The Chinese versions of self-reported measures of PA, PA-related social environment, and PA-related psychological constructs showed acceptable reliabilities and validities. (d) Correlates of PA (k = 18). The correlates of PA include physical environment, social environment, physical factors, psychological factors, and multiple correlates, which is in line with the social-ecological model. (e) Interventions for promoting PA (k = 10). PA interventions among Hong Kong children were conducted for healthy children, children with special educational needs, and children with cancer. Overall, there is a growing volume of PA research among children in Hong Kong in the recent decade. Yet, there is a lack of high-quality research for measuring, understanding, and promoting PA among Hong Kong children. It is highly recommended that future PA research among children should pay more attention on the preschoolers, adopting robust research design (e.g., randomized controlled trials), recruiting large and representative sample, and collecting device-assessed data.
Acceptability of Telemedicine Features to Promote Its Uptake in Practice: A Survey of Community Telemental Health Providers
Authors: Bunnell Brian E. , Barrera Janelle F. , Paige Samantha R. , Turner Dylan , Welch Brandon M.
Published: November 2020

Understanding what motivates mental health providers to use telemedicine (i.e., telemental health) is critical for optimizing its uptake, especially during unprecedented times (e.g., the COVID-19 pandemic). Drawing from the Technology Acceptance Model (TAM), this report examined the characteristics of telemental health providers and how the acceptability of telemedicine features contributes to their intention to use the technology more often in practice. Telemental health providers (N = 177) completed an online survey between March and May 2019. Most providers (75%) spent less than 25% of their work-week using telemedicine, but 70% reported an intention to use telemedicine more in the future. The belief that telemedicine affords greater access to patients, work-life balance, flexibility in providing care, and the opportunity to be at the forefront of innovative care were significant predictors of intentions to use the technology more in the future. Other significant predictors included needing assistance to coordinate insurance reimbursements, manage a successful telemedicine practice, and integrate the telemedicine program with other health IT software. Findings have important implications for increasing the frequency of telemedicine use among telemental health providers. Future research and practice should leverage providers’ positive beliefs about telemedicine acceptability and consider their needs to enhance its uptake.
Responsible Communication of Romanian Companies for Ensuring Public Health in a COVID-19 Pandemic Context
Authors: Hategan Camelia-Daniela , Curea-Pitorac Ruxandra-Ioana , Hategan Vasile-Petru
Published: November 2020

The COVID-19 pandemic has forced companies to respond to the threat of this risk and innovate in corporate governance. In order to reduce the risk of illness, one of the most applied measures by all companies was social distancing, but to avoid human interaction, companies had to adapt their communication strategies. The objective of the paper is to assess the risk management of Romanian-listed companies associated with COVID-19 focusing on their business communication with shareholders and stakeholders. To emphasis the communication we have chosen to analyze all public reports during the state of emergency of the companies listed on the main market at the Bucharest Stock Exchange. The empirical analysis consists of a panel data econometric model using maximum likelihood random-effects regression and a logistical regression to highlight the correlations between the dependent variables Public Reports and Business Continuity Plan and the analyzed independent variables. The study showed that in most cases, the companies had at least one public report, especially the one related to the annual shareholders meeting, a percentage of 21% of companies had two public reports, and only 17% of companies have published three or more reports. The companies that communicated the most were the ones belonging to the premium trading category, and the number of published reports was influenced by the communication evaluation indicator, profitability and by the announcement of the donations made.
Relationship between Quality of Life and Sociodemographic, Physical and Mental Health Variables in People over 65 in the Community of Madrid
Authors: Ausín Berta , Zamorano Alba , Muñoz Manuel
Published: November 2020

Except in the case of depression, there are few studies that analyze mental health variables related to quality of life (QoL) in people over 65 years of age. The objective of this study is to analyze the relationship between QoL and the following variables: sociodemographic and physical and mental health of people over 65 years of age. The sample was randomly selected and consists of men and women between 65 and 84 years of age (N = 555) from the Community of Madrid. Mental disorders were evaluated with the CIDI65+ interview and QoL with the WHOQoL-BREF scale. Means, ANOVA and multiple linear regression analyses were performed. Women have worse QoL than men and QoL worsens with age. The regression model for the dependent variable “WHOQoL BREF Scale” explains 41.43% of the variance (R2 = 0.413). The variables that have the greatest impact on QoL are as follows: a greater number of physical and psychological symptoms, experiencing financial difficulties and the presence of a psychological disorder, while continuing to work has a positive effect on QoL. Physical and mental disorders have a similar impact on QoL. The presence of a greater number of psychological symptoms (without necessarily fulfilling the criteria of a mental disorder) is a predictive variable of worse QoL. Mental health has a burden on the QoL of people over 65 years of age that is as powerful as physical health.
Youth Exposure to Hate in the Online Space: An Exploratory Analysis
Authors: Harriman Nigel , Shortland Neil , Su Max , Cote Tyler , Testa Marcia A. , Savoia Elena
Published: November 2020

Today’s youth have extensive access to the internet and frequently engage in social networking activities using various social media platforms and devices. This is a phenomenon that hate groups are exploiting when disseminating their propaganda. This study seeks to better understand youth exposure to hateful material in the online space by exploring predictors of such exposure including demographic characteristics (age, gender, and race), academic performance, online behaviors, online disinhibition, risk perception, and parents/guardians’ supervision of online activities. We implemented a cross-sectional study design, using a paper questionnaire, in two high schools in Massachusetts (USA), focusing on students 14 to 19 years old. Logistic regression models were used to study the association between independent variables (demographics, online behaviors, risk perception, parental supervision) and exposure to hate online. Results revealed an association between exposure to hate messages in the online space and time spent online, academic performance, communicating with a stranger on social media, and benign online disinhibition. In our sample, benign online disinhibition was also associated with students’ risk of encountering someone online that tried to convince them of racist views. This study represents an important contribution to understanding youth’s risk factors of exposure to hateful material online.
Is Irritable Bowel Syndrome Considered in Clinical Trials on Physical Therapy Applied to Patients with Temporo-Mandibular Disorders? A Scoping Review
Authors: Rodrigues-de-Souza Daiana P. , Paz-Vega Javier , Fernández-de-las-Peñas César , Cleland Joshua A. , Alburquerque-Sendín Francisco
Published: November 2020

The aim of the current scoping review was to identify if the presence of irritable bowel syndrome was included as eligibility criteria of participants included in clinical trials investigating the effects of physical therapy in individuals with temporomandibular pain disorders (TMDs). A systematic electronic literature search in the Web of Science database was conducted. Scientifically relevant, randomized clinical trials (those cited in other studies at least 5 times, or clinical trials published in high-impact journals, i.e., first and second quartiles (Q1-Q2) of any category of the Journal Citation Report (JCR)) evaluating the effects of any physical therapy intervention in patients with TMDs were included. The Physiotherapy Evidence Database (PEDro) scale was used to evaluate the methodological quality of the selected trials. Authors affiliated to a clinical or non-clinical institution, total number of citations, objective, sex/gender, age, and eligibility criteria in each article were extracted and analyzed independently by two authors. From a total of 98 identified articles, 12 and 19 clinical trials were included according to the journal citation criterion or JCR criterion, respectively. After removing duplicates, a total of 23 trials were included. The PEDro score ranged from 4 to 8 (mean: 6.26, SD: 1.48). Based on the eligibility criteria of the trials systematically reviewed, none considered the presence of comorbid irritable bowel syndrome in patients with TMDs. The comorbidity between TMDs and irritable bowel syndrome is not considered within the eligibility criteria of participants in highly cited clinical trials, or published in a high-impact journal, investigating the effects of physical therapy in TMDs.
Effectiveness of Innovation Media for Improving Physical Distancing Compliance during the COVID-19 Pandemic: A Quasi-Experiment in Thailand
Authors: Chutiphimon Hattaya , Thipsunate Apinya , Cherdchim Atigun , Boonyaphak Bootsarakam , Vithayasirikul Panat , Choothong Patiphan , Vichathai Swit , Ngamchaliew Pitchayanont , Vichitkunakorn Polathep
Published: November 2020

To flatten the curve of COVID-19 infections, with no effective pharmacological interventions or vaccine available in the imminent future, public health responses must continue to rely on non-pharmacological interventions. We developed three innovation media to promote physical distancing compliance (i.e., a fearful picture, a red one-way arrow sign, and a norm-speech sticker). This study aimed to compare physical distancing compliance between our interventions and conventional interventions. Our study was a quasi-experiment, and we observed a representative sample of university canteen customers via closed-circuit television (CCTV). Each intervention was monitored over non-prime-time hours, per day, on 6–9 August 2020. Among the 400 participants (100 participants in each group), their age group, gender, and physical distancing practices were observed in a university canteen. The number of failures of physical distancing ranged between 93.8% and 17.6%, and on average between 84.2% and 34.2%, dependent on the intervention and the marking point. There were no statistically significant differences in promoting physical distancing compliance between our interventions compared with conventional interventions. However, the participants tended to practice physical distancing at the back of the queue more than at the front, regardless of the interventions.
Circular RNA, the Key for Translation
Authors: Prats Anne-Catherine , David Florian , Diallo Leila H. , Roussel Emilie , Tatin Florence , Garmy-Susini Barbara , Lacazette Eric
Published: November 2020

It was thought until the 1990s that the eukaryotic translation machinery was unable to translate a circular RNA. However internal ribosome entry sites (IRESs) and m6A-induced ribosome engagement sites (MIRESs) were discovered, promoting 5′ end-independent translation initiation. Today a new family of so-called “noncoding” circular RNAs (circRNAs) has emerged, revealing the pivotal role of 5′ end-independent translation. CircRNAs have a strong impact on translational control via their sponge function, and form a new mRNA family as they are translated into proteins with pathophysiological roles. While there is no more doubt about translation of covalently closed circRNA, the linearity of canonical mRNA is only theoretical: it has been shown for more than thirty years that polysomes exhibit a circular form and mRNA functional circularization has been demonstrated in the 1990s by the interaction of initiation factor eIF4G with poly(A) binding protein. More recently, additional mechanisms of 3′–5′ interaction have been reported, including m6A modification. Functional circularization enhances translation via ribosome recycling and acceleration of the translation initiation rate. This update of covalently and noncovalently closed circular mRNA translation landscape shows that RNA with circular shape might be the rule for translation with an important impact on disease development and biotechnological applications.
Cachexia, a Systemic Disease beyond Muscle Atrophy
Authors: Wyart Elisabeth , Bindels Laure B. , Mina Erica , Menga Alessio , Stanga Serena , Porporato Paolo E.
Published: November 2020

Cachexia is a complication of dismal prognosis, which often represents the last step of several chronic diseases. For this reason, the comprehension of the molecular drivers of such a condition is crucial for the development of management approaches. Importantly, cachexia is a syndrome affecting various organs, which often results in systemic complications. To date, the majority of the research on cachexia has been focused on skeletal muscle, muscle atrophy being a pivotal cause of weight loss and the major feature associated with the steep reduction in quality of life. Nevertheless, defining the impact of cachexia on other organs is essential to properly comprehend the complexity of such a condition and potentially develop novel therapeutic approaches.