bluuebunny/crossref_metadata_2025 huggingface dataset:
Haplotype in SERPINA1 (AAT) Is Associated with Reduced Risk for COPD in a Mexican Mestizo Population
Authors: Ponce-Gallegos Marco Antonio , Pérez-Rubio Gloria , García-Carmona Adriana , García-Gómez Jesús , Hernández-Zenteno Rafael , Ramírez-Venegas Alejandra , Falfán-Valencia Ramcés
Published: December 2019

Protease inhibitor S (PiS) and protease inhibitor Z (PiZ) variants in the SERPINA1 gene are the main genetics factors associated with COPD; however, investigations about other polymorphisms are scanty. The aim of this study was to evaluate two missense single nucleotide polymorphisms (SNPs) (rs709932 and rs1303) in the SERPINA1 gene in Mexican mestizo patients with chronic obstructive pulmonary disease (COPD) related to tobacco smoking and biomass-burning exposure. 1700 subjects were genotyped and divided into four groups: COPD related to tobacco smoking (COPD-S, n = 297), COPD related to biomass-burning exposure (COPD-BB, n = 178), smokers without COPD (SWOC, n = 674), and biomass-burning exposed subjects (BBES, n = 551) by real-time PCR. Moreover, the patients’ groups were divided according to their exacerbations’ frequency. We carried out a haplotype analysis. We did not find differences in allele and genotype frequencies between groups in unadjusted and adjusted analyses, neither with these SNPs and lung function decline. Exacerbations’ frequency is not associated with these SNPs. However, we found a haplotype with major alleles (CT) associated with reduced risk for COPD (p < 0.05). Our analysis reveals that SNPs different from PiS and PiZ (rs709932 and rs1303) in the SERPINA1 gene are not associated with COPD and lung function decline in a Mexican mestizo population. However, a haplotype shaped by both major alleles (CT haplotype) is associated with reduced risk for COPD.
Immediate and Late Effects of Early Weaning on Rat Gastric Cell Differentiation
Authors: Teles Silva Melissa , Mesquita da Silva Kethleen , Campos Rattes Isadora , Maria Agostini Zonta Gizela , Vasques da Costa Aline , Galvão Figueredo Costa Raquel , Karen Cordeiro Nogueira Ludimila , Ogias Daniela , Gama Patricia
Published: December 2019

Background: Gastric glands grow and cells reach differentiation at weaning in rats. By considering that early weaning (EW) can affect the timing of development, we aimed to compare molecular and cellular markers of differentiation in pups and adults. Methods: Wistar rats were separated into suckling-control (S) and EW groups at 15 days. Stomachs were collected at 15, 18, and 60 days for RNA and protein extraction, and morphology. Results: After EW, the expression of genes involved in differentiation (Atp4b, Bhlha15 and Pgc) augmented (18 days), and Atp4b and Gif were high at 60 days. EW increased the number of zymogenic cells (ZC) in pups and adults and augmented mucous neck cells only at 18 days, whereas parietal and transition cells (TC) were unchanged. Conclusions: EW affected the gastric mucosa mostly in a transient manner as the changes in gene expression and distribution of differentiated cells that were detected in pups were not fully maintained in adults, except for the size of ZC population. We concluded that though most of EW effects were immediate, such nutritional change in the infancy might affect part of gastric digestive functions in a permanent manner, as some markers were kept unbalanced in the adulthood.
High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra
Authors: Kao Yu-Chia , Wei Wei-Yen , Tsai Kuen-Jer , Wang Liang-Chao
Published: December 2019

Although several epidemiologic and animal studies have revealed correlations between obesity and neurodegenerative disorders, such as Parkinson disease (PD), the underlying pathological mechanisms of obesity-induced PD remain unclear. Our study aimed to assess the effect of diet-induced obesity on the brain dopaminergic pathway. For five months, starting from weaning, we gave C57BL/6 mice a high-fat diet (HFD) to generate an obese mouse model and investigate whether the diet reprogrammed the midbrain dopaminergic system. Tyrosine hydroxylase staining showed that the HFD resulted in fewer dopaminergic neurons in the substantia nigra (SN), but not the striatum. It also induced neuroinflammation, with increased astrogliosis in the SN and striatum. Dendritic spine density in the SN of HFD-exposed mice decreased, which suggested that prolonged HFD altered dopaminergic neuroplasticity. All three peroxisome proliferator-activated receptor (PPAR) subtype (PPAR-α, PPAR-β/δ, PPAR-γ) levels were significantly reduced in the SN and the ventral tegmental area of HFD mice when compared to those in controls. This study showed that a prolonged HFD induced neuroinflammation, suppressed PPAR levels, caused degeneration of midbrain dopaminergic neurons, and resulted in symptoms reminiscent of human PD. To our knowledge, this is the first study documenting the effects of an HFD on PPARs in dopaminergic neurons.
Phosphorylation Signaling in APP Processing in Alzheimer’s Disease
Authors: Zhang Tao , Chen Dongmei , Lee Tae Ho
Published: December 2019

The abnormal accumulation of amyloid-β (Aβ) in the central nervous system is a hallmark of Alzheimer’s disease (AD). The regulation of the processing of the single- transmembrane amyloid precursor protein (APP) plays an important role in the generation of Aβ in the brain. The phosphorylation of APP and key enzymes involved in the proteolytic processing of APP has been demonstrated to be critical for modulating the generation of Aβ by either altering the subcellular localization of APP or changing the enzymatic activities of the secretases responsible for APP processing. In addition, the phosphorylation may also have an impact on the physiological function of these proteins. In this review, we summarize the kinases and signaling pathways that may participate in regulating the phosphorylation of APP and secretases and how this further affects the function and processing of APP and Aβ pathology. We also discuss the potential of approaches that modulate these phosphorylation-signaling pathways or kinases as interventions for AD pathology.
N-(2-Arylmethylthio-4-Chloro-5-Methylbenzenesulfonyl)amide Derivatives as Potential Antimicrobial Agents—Synthesis and Biological Studies
Authors: Żołnowska Beata , Sławiński Jarosław , Garbacz Katarzyna , Jarosiewicz Małgorzata , Kawiak Anna
Published: December 2019

Rising resistance of pathogenic bacteria reduces the options of treating hospital and non-hospital bacterial infections. There is a need to search for newer chemotherapies that will show antimicrobial ability against planktonic cells as well as bacterial biofilms. We have synthesized a series of N-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)amides, namely, molecular hybrids, which include a 2-mercaptobenzenosulfonamide fragment and either cinnamic or cyclohexylpropionic acid residues. The antimicrobial activity of compounds 8–17 was evaluated on Gram-positive, Gram-negative bacteria and fungal species. Experiments took into account investigation of antibacterial activity against planktonic cells as well as biofilms. Compounds 8–17 showed high bacteriostatic activity against staphylococci, with the most active molecules 10 and 16 presenting low MIC values of 4–8 μg/mL against reference methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) strains as well as clinical isolates. Compounds 10 and 16 also showed an ability to inhibit biofilms formed by MRSA and MSSA. The potential of 10 and 16 as antibiofilm agents was supported by cytotoxicity assays that indicated no cytotoxic effect either on normal cells of human keratinocytes or on human cancer cells, including cervical, colon, and breast cancer lines.
Macroalgae Derived Fungi Have High Abilities to Degrade Algal Polymers
Authors: Patyshakuliyeva Aleksandrina , Falkoski Daniel L. , Wiebenga Ad , Timmermans Klaas , de Vries Ronald P.
Published: December 2019

Marine fungi associated with macroalgae are an ecologically important group that have a strong potential for industrial applications. In this study, twenty-two marine fungi isolated from the brown seaweed Fucus sp. were examined for their abilities to produce algal and plant biomass degrading enzymes. Growth of these isolates on brown and green algal biomass revealed a good growth, but no preference for any specific algae. Based on the analysis of enzymatic activities, macroalgae derived fungi were able to produce algae specific and (hemi-)cellulose degrading enzymes both on algal and plant biomass. However, the production of algae specific activities was lower than the production of cellulases and xylanases. These data revealed the presence of different enzymatic approaches for the degradation of algal biomass by macroalgae derived fungi. In addition, the results of the present study indicate our poor understanding of the enzymes involved in algal biomass degradation and the mechanisms of algal carbon source utilization by marine derived fungi.
Does Competitive Intensity Moderate the Relationships between Sustainable Capabilities and Sustainable Organizational Performance in New Ventures?
Authors: Zhang Haili , Wang Yufan , Song Michael
Published: December 2019

Competitive intensity presents challenges to new ventures. Capabilities may lead to sustainable new venture performance. Yet, few studies have explored how competitive intensity moderates the effects of capabilities on sustainable new venture performance. Based on capability-based view, this study develops a research model to investigate how new ventures translate capabilities (marketing, technology, market-linking, and information technology capabilities) to achieve sustainability of new venture growth and performance under the different levels of competitive intensity. Using data collected from 146 U.S. new ventures, this study uses ordinary least squares regression analysis to test the research model and employs “pick-a-point” approach to examine how capabilities affect sustainable new venture performance at different levels of competitive intensity. The empirical results suggest that increasing competitive intensity decreases, not increases, the positive effects of marketing capabilities on performance. When competitive intensity is very high, the positive effects of marketing capabilities on performance become insignificant. In contrast, the positive effects of market-linking capabilities on performance increase, not decrease, as competitive intensity increases. For technology and information technology capabilities, there are no moderating effects of competitive intensity. The theoretical and managerial implications are suggested for sustainable entrepreneurship and sustainable development of new enterprises.
Serious Solutions for Unsteady Axisymmetric Flow over a Rotating Stretchable Disk with Deceleration
Authors: Sadiq Muhammad Adil
Published: January 2020

In this article, the author has examined the unsteady flow over a rotating stretchable disk with deceleration. The highly nonlinear partial differential equations of viscous fluid are simplified by existing similarity transformation. Reduced nonlinear ordinary differential equations are solved by homotopy analysis method (HAM). The convergence of HAM solutions is also obtained. A comparison table between analytical solutions and numerical solutions is also presented. Finally, the results for useful parameters, i.e., disk stretching parameters and unsteadiness parameters, are found.
R0 Estimation for the African Swine Fever Epidemics in Wild Boar of Czech Republic and Belgium
Authors: Marcon Andrea , Linden Annick , Satran Petr , Gervasi Vincenzo , Licoppe Alain , Guberti Vittorio
Published: December 2019

African swine fever (ASF) is a contagious haemorrhagic fever that affects both domesticated and wild pigs. Since ASF reached Europe wild boar populations have been a reservoir for the virus. Collecting reliable data on infected individuals in wild populations is challenging, and this makes it difficult to deploy an effective eradication strategy. However, for diseases with high lethality rate, infected carcasses can be used as a proxy for the number of infected individuals at a certain time. Then R0 parameter can be used to estimate the time distribution of the number of newly infected individuals for the outbreak. We estimated R0 for two ASF outbreaks in wild boar, in Czech Republic and Belgium, using the exponential growth method. This allowed us to estimate both R0 and the doubling time (Td) for those infections. The results are R0 = 1.95, Td = 4.39 for Czech Republic and R0 = 1.65, Td = 6.43 for Belgium. We suggest that, if estimated as early as possible, R0 and Td can provide an expected course for the infection against which to compare the actual data collected in the field. This would help to assess if passive surveillance is properly implemented and hence to verify the efficacy of the applied control measures.
Ornithobacterium rhinotracheale: An Update Review about An Emerging Poultry Pathogen
Authors: Barbosa Eunice Ventura , Cardoso Clarissa Varajão , Silva Rita de Cássia Figueira , Cerqueira Aloysio de Mello Figueiredo , Liberal Maíra Halfen Teixeira , Castro Helena Carla
Published: December 2019

Respiratory diseases in birds generate sanitary and economic impacts and may be related to the environment and climate. Mycoplasma gallisepticum, Ornithobacterium rhinotracheale (ORT), Pasteurella multocida, Avibacterium paragallinarum, Escherichia coli, Riemerella anatipestifer, and Bordetella avium are among the most important avian respiratory pathogens. ORT is responsible for causing ornitobacteriosis, a disease characterized by clinical signs ranging from mild to severe respiratory conditions, with high mortality rates, mainly affecting turkeys and chickens. The first report of ornitobacteriosis was in 1981 in Germany. Despite its importance, few studies on ORT have been published. In addition, the presence of this pathogen has been neglected in poultry farms, mainly due to the lack of appropriate diagnostic protocols. The lack of correct isolation and diagnostic protocols along with inappropriate use of antimicrobial agents have been contributing to treatment failure. Due to its economic importance to the poultry industry, ornitobacteriosis should be monitored and included in national programs for the prevention and control of avian respiratory diseases. This review aimed to update and discuss important issues related to ORT since this pathogen has great economic and sanitary implications for the chicken production chain.
Los años cruciales. Filosofía en la Argentina
Authors: Fernández Vega José
Published: December 2019

Cuadernos de filosofía publicó su primer número en 1948 y es posible partir de ese acontecimiento para hilvanar un relato de la historia de la filosofía argentina en el siglo XX. Desde sus inicios fue editada por la Facultad de Filosofía y Letras de la Universidad de Buenos Aires (UBA). Según los adversarios de ese complejo proceso que al cabo de unos años llevaría al peronismo al poder, para la época de aparición de la revista la universidad ya había caído en manos de un grupo que expulsó de ella a la vanguardia de las ideas, exoneró a calificados profesores opositores y arruinó una convivencia que, más allá de unas moderadas tensiones internas, había caracterizado la vida en los claustros de humanidades hasta 1943. En ese año un giro autoritario se habría adueñado del país y pronto también de sus instituciones de enseñanza superior. El fascismo europeo entraba en su eclipse definitivo pero, en Argentina, y no solo en ella, había quienes sostenían que una variante del totalitarismo comenzaba a florecer en el país bajo el amparo de las Fuerzas Armadas y de la Iglesia católica.
¿Qué hay de política en la filosofía? Ocho ensayos, de Lucila Svampa
Authors: Taccetta Natalia
Published: December 2019

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GEBELERİN UYKU ÖZELLİKLERİNİN PRENATAL BAĞLANMA İLE İLİŞKİSİ
Authors: NACAR Gülçin , TİMUR TAŞHAN Sermin
Published: January 2020

Araştırma gebelerin uyku özelliklerinin
prenatal bağlanma ile ilişkisini belirlemek amacıyla yapılmıştır. Araştırma ilişki arayıcı tanımlayıcı
olarak planlanmıştır. Araştırma, Aralık
2016-Haziran 2017 tarihleri arasında
Türkiye'nin doğusundaki bir devlet hastanesinde yürütülmüştür. Araştırmanın
örneklemini, güç analizine göre 0,05 etki büyüklüğünde ve %5 yanılgı düzeyi ile
belirlenen %95 güven aralığında %98 oranla evreni temsil gücüne sahip 977 gebe
oluşturmuştur. Verilerin elde edilmesinde “Katılımcı Bilgi Formu”, “Kadın
Sağlığı İnisiyatifi Uykusuzluk Ölçeği (KSİUÖ)” ve ‘‘Prenatal Bağlanma Envanteri
(PBE)” kullanılmıştır. İstatistiksel değerlendirmede; yüzde, ortalama, standart
sapma, bağımsız gruplarda t testi, tek yönlü varyans analizi (ANOVA), bonferroni
ve lojistik regresyon analizleri kullanılmıştır.Araştırmada gebelerin %66,7’sinin
uykusuzluk problemi olduğu, %52,4’ünün 7 saatten az uyuduğu, %85,4’ünün gebelik
dönemindeki uyku alışkanlığında değişiklik olduğu bulunmuştur. Araştırmada öğrenim
durumunun, bebeğin cinsiyetinin, gebelik trimesterinin uykusuzluk için önemli
yordayıcılar olduğu tespit edilmiştir (p<0.05). Gebelerin uyku süresi azaldıkça
prenatal bağlanma düzeylerinin arttığı görülmüştür (p: 0.022).

Gebelikte uyku süresi ile prenatal
bağlanma birlikte değerlendirilmeli ve anne, bebek sağlığı için gerekli
önlemler alınmalıdır.
STEM Eğitimi Alan Öğretmenlerin Eleştirel Düşünme Eğilimlerinin Belirlenmesi
Authors: EVCİM İsmail , UMDU TOPSAKAL Ünsal
Published: January 2020

21. yy becerileri arasında yer alan
eleştirel düşünme becerisi, günümüzde doğru bilginin edinilmesi açısından
önemlidir. STEM eğitimine ilgi duyan ve bu alanda kendini geliştiren bir
öğretmenin eleştirel düşünme eğilimi de farklı olabilir. Bu bağlamda STEM,
Arduino veya Robotik eğitimi alan 76 öğretmenin; eleştirel düşünme eğilim
düzeylerini belirleme, yaş, mesleki deneyim ve cinsiyet açısından fark olup
olmadığını belirlemek amaçlanmıştır. Araştırma bulgularında, STEM eğitimi alan
öğretmenlerin genel olarak orta üstü seviyede eleştirel düşünme eğilimlerine
sahip oldukları, alt boyutlarda alınan puanların yüksekten aza doğru
Meraklılık, Analitiklik, Açık Fikirlilik, Sistematiklik, Kendine Güven ve
Doğruyu Arama şeklinde sıralandığı söylenebilir. STEM Eğitimi alan
öğretmenlerin, eleştirel düşünme eğilimleri yaş gruplarına bağlı olarak
incelendiğinde; 31-35 yaş gruptakilerin, 22-30 yaş gruptakilere göre daha
yüksek açık fikirliliğe sahip oldukları, meraklılık alt boyutunda ise 36 yaş ve
üstü gruptakilerin, 31-35 yaş ve 22-30 
yaş gruptakilere göre daha meraklı oldukları görülmüştür. Ayrıca
meraklılık alt boyutunda 36 yaş ve üstü öğretmenlerin eleştirel düşünme
eğilimlerinin kendilerinden daha genç olanlara göre yüksek seviyede olmasının
ilgili alanda derinleşmenin etkisi olarak söylenebilir. STEM Eğitimi alan
öğretmenlerin, eleştirel düşünme eğilimleri mesleki deneyime bağlı olarak
incelendiğinde; 21 yıl ve üzeri grubun, 11-20 yıl ve 0-10 yıl mesleki deneyime
sahip gruplardakilere göre kendilerine daha çok güvendikleri tespit edilmiş ve
meraklılık boyutunda 21 yıl ve üstü mesleki deneyime sahip  gruptakilerin, 0-10 yıl arası mesleki deneyime
sahip gruptakilere göre daha meraklı oldukları gözlenmiştir. STEM Eğitimi alan
öğretmenlerin, eleştirel düşünme eğilimleri cinsiyete bağlı olarak
incelendiğinde; analitiklik ve kendine güven boyutlarında farklılık olduğu
ortaya çıkmış ve erkeklerin lehine olduğu görülmüştür.
Rusçada “Само-” Ön Eki ile Kullanılan Sözcükler
Authors: ELTUT KALENDER Nükhet
Published: January 2020

Her
dilin sözcük yapım yöntemleri birbirine benzemektedir. Rus dilinde sözcük
yapımı morfemler ile gerçekleştirilmektedir. Morfemler prefiks (ön ek), suffiks
(yapım eki), interfiks (sözcük bağlayıcı iç ek), okonçaniye (son ek) ve
postfiks (ardıl ek) gibi ekleri içermektedir. Ait oldukları isim, sıfat, eylem
gruplarına göre ayırt edici ekler alarak yeni Rusça sözcükler
türetilebilmektedir.

Bu çalışmada temel olarak “само-” ön eki ile türetilen
sözcük yapılarının incelenmesi amaçlanmaktadır. Rus dilinde bu ön ek ile
türetilen pek çok sözcük mevcuttur. “Само-” ön eki ardından gelen sözcüğe genellikle “kendi
başına” ya da “kendi kendine” anlamını katmaktadır. Söz konusu ek ile ardından
gelen sözcük parçacığı birleşerek yeni bir sözcük oluşturur. “Само-” ön ekinin Rusça sözcük
yapımındaki rolü ve bu ön ek sayesinde ortaya çıkan yeni sözcüğün “kendi
başına” ya da “kendi kendine” ifadeleri kullanılmaksızın kazandığı sözlük
anlamlarının açıklanması amaçlanmaktadır.
Studio delle immagini e delle metafore sul timore del Signore in Ben Sira
Authors: Palmisano Maria Carmela
Published: December 2019

L'articolo presenta lo studio del timore del Signore nel libro del Siracide a partire da Sir 1 che riveste un valore programmatico nell'opera sapienziale. Il contributo presenta quattro diverse prospettive rilevate in Sir 1, secondo le quali Ben Sira presenta ai discepoli il timore del Signore. Le quattro prospettive ricorrono anche in altri passi del libro (Sir 2–51). A queste viene aggiunta in seguito una quinta, quella storica, presente solo in un testo dell'Elogio dei padri. Il contributo si sofferma ad analizzare in particolare l'aspetto simbolico e metaforico del linguaggio usato da Ben Sira per avvicinare al discepolo il timore del Signore nei suoi aspetti di bontà, bellezza, gioia e nel suo dinamismo che guida l'uomo sui sentieri dell'amore.
The Christological Aspects of Hebrew Ideograms
Authors: Petrović Predrag
Published: December 2019

Abstract: The linguistic form of the Hebrew Old Testament retained its ancient ideogram values included in the mystical directions and meanings originating from the divine way of addressing people. As such, the Old Hebrew alphabet has remained a true lexical treasure of the God-established mysteries of the ecclesiological way of existence. The ideographic meanings of the Old Hebrew language represent the form of a mystagogy through which God spoke to the Old Testament fathers about the mysteries of the divine creation, maintenance, and future re-creation of the world. Thus, the importance of the ideogram is reflected not only in the recognition of the Christological elements embedded in the very structure of the Old Testament narrative, but also in the ever-present working structure of the existence of the world initiated by the divine economy of salvation. In this way both the Old Testament and the New Testament Israelites testify to the historicizing character of the divine will by which the world was
Sklepanje krščanskega zakona na Zahodu in Vzhodu od pozne antike do zgodnjega srednjega veka
Authors: Saje Andrej
Published: December 2019

Razprava se osredotoča na razvoj krščanskih poročnih praks od tretjega stoletja do začetka drugega tisočletja, ko se na Zahodu glede na Vzhod na tem področju utrdi drugačna praksa. Kristjani prvih stoletij so se poročali v skladu z domačimi običaji. Ob koncu antike se začne v vzhodni Cerkvi pod vplivom semitskih kultur močneje poudarjati sakralni značaj zakona. Posledično pomen pridobiva liturgični poročni obred v Cerkvi z blagoslovom duhovnika, kar sčasoma postane redna praksa, potrjena tudi s cesarskimi odloki. Za razliko od bizantinske tradicije se na Zahodu pod vplivom rimskega prava kot bistveni tvorni element sklenitve zakona izrazito poudarja privolitev zaročencev, duhovniški blagoslov novoporočencev pa se zaradi pastoralnih razlogov samo priporoča in ostane fakultativen. Cerkev je zaročence zgolj spodbujala, naj se zaradi velikega pomena družine poročajo z javnim obredom pred Cerkvijo. Skupna točka obeh tradicij je v učenju, da zakon nastane s privolitvijo zaročencev, razlika pa je v vrednotenju duhovniškega blagoslova in vprašanja, ali je duhovnik za sklenitev poroke bistven. Na Vzhodu je cerkveni obred poroke obvezen od enajstega stoletja dalje, na Zahodu pa enotno cerkveno obliko poroke dobimo šele v šestnajstem stoletju.
»Bratje Čehi« v ljubljanskem bogoslovju (1885–1897)
Authors: Šimac Miha
Published: December 2019

V letih od 1885 do 1897 so v ljubljansko bogoslovje prihajali duhovniški kandidati s Češke in Moravske. Na Kranjskem je namreč duhovnikov primanjkovalo, na Češkem in Moravskem pa je v tem obdobju zanimanje za duhovne poklice cvetelo. Temu primerno so bila češka in moravska bogoslovna semenišča zapolnjena in mladi kandidati so si morali iskati mesta po drugih semeniščih v monarhiji. Tržaško-koprski škof Ivan Glavina (škof v letih 1882–1895) je tako dal pobudo ter povabil češke in moravske kandidate v centralno goriško semenišče ; odziv je bil velik in mnogi so pozneje uspešno delovali kot dušni pastirji v njegovi škofiji. Prošnje mladih čeških kandidatov pa so se znašle tudi v Ljubljani. Prispevek želi na podlagi arhivskega gradiva, časopisnih notic, pa tudi spominov na kratko orisati in osvetliti omenjeno obdobje prisotnosti »bratov Čehov«, ki so bili pozneje vpeti v življenje in skrb za dušni blagor ljudi, v ljubljanskem bogoslovju.
El análisis crítico de discurso en textos de políticas públicas: lineamientos para una praxis investigativa
Authors: Peña Ochoa Mónica
Published: December 2019

Este trabajo busca sistematizar la experiencia del análisis crítico de discurso (ACD) de textos que son parte del campo político, a partir de los principios propuestos por el lingüista británico Norman Fairclough, con algunos ejemplos empíricos, agregando algunos elementos de la teoría feminista. Se indaga en presupuestos funcionales como la necesidad de este tipo de análisis en el contexto neoliberal latinoamericano, epistemológicos como la imposibilidad del análisis, y ontológicos, en la relación entre discurso y materialidad y se hace una propuesta metodológica que incluye intertextualidades y textualidades. Se finaliza con una propuesta de pensar el ACD y otras formas de investigación crítica asumiendo un programa de investigación que incluya el posicionamiento político del investigador junto con aspectos que aseguren validez y viabilidad a las investigaciones.
Verón entre mundos: ¿hacia una semio-antropología?
Authors: Gómez-Mejía Gustavo , Le Marec Joëlle , Souchier Emmanuël , Cingolani Gastón
Published: December 2019

El presente artículo se centra en la postura intelectual de Eliseo Verón, buscando reinterpretar su trayectoria y sus principales aportes teóricos al campo de las Ciencias de la Información y de la Comunicación en Francia. En retrospectiva, los múltiples ámbitos culturales, profesionales e interdisciplinarios que habitan los trabajos de Verón son analizados como “mundos” que dan forma al oficio del investigador, e interrogan la producción del conocimiento a través de diversas instituciones. Tanto las articulaciones como los desfases entre dichos mundos permiten entender cómo las preocupaciones transversales de un enfoque “sociosemiótico” (característico de las referencias veronianas francesas) pueden inspirar un amplio programa semio-antropológico en el campo contemporáneo de la investigación.
PENGARUH EDUKASI GIZI TERHADAP PENGETAHUAN DAN KEBIASAAN MAKAN PADA PESERTA PROGRAM PENGELOLAAN PENYAKIT KRONIS (PROLANIS) DIABETES MELLITUS TIPE 2 DI KELURAHAN PENGGILINGAN I ELOK JAKARTA TIMUR
Authors: Septiani Septiani
Published: December 2019

bertujuan untuk mengetahui pengaruh konseling gizi terhadap pengetahuan dan kebiasaan makan (asupan energi, protein, lemak, karbohirat, dan serat). Design penelitian adalah pra-experimental with one group pre test and post test. Metode pengambilan sampel purposive sampling berjumlah 58 orang peserta prolanis Diabetes Mellitus Tipe 2. Instrumen dalam penelitian ini, yaitu form karakteristik responden, form pengetahuan, terapi farmakologi, form konseling gizi, dan kuesioner food recall 2x24 hours. Analisis penelitian yang digunakan yaitu McNemar test. Hasil penelitian menunjukkan ada pengaruh edukasi gizi terhadap pengetahuan dengan p=0,001 (p<0,005) dan kebiasaan makan (asupan protein dengan p=0,001, lemak dengan p=0,021, karbohidrat dengan p=0,003, dan serat dengan p=0,001) (p<0,005) responden. Namun tidak ada pengaruh edukasi terhadap asupan energi dengan p=0,648 (p>0,005) responden.
SMEs and Economic Growth in Nigeria: An Autoregressive Distributed Lag Approach
Authors: Oyeniran Ishola Wasiu , David Oladipo Olalekan , Ajayi Oluseyi
Published: December 2019

This empirical study adopts an autoregressive distributed lag approach in order to examine how small and medium enterprises (SMEs) have contributed to economic growth in Nigeria between 1981 and 2013. We find that investment in SMEs has had a significant and positive impact on economic growth in the country. Given that Nigeria is economically underdeveloped, it is essential that the majority of its (largely rural) population be integrated into the process of economic development through entrepreneurship in small businesses. This means encouraging further investment in SMEs and prioritizing their access to credit facilities, infrastructure development, and capacity building to promote long-run socioeconomic development through this medium.
The Impact of Cost Leadership Strategy and Financial Management Control Systems on Organizational Performance in Pakistan’s Services Sector
Authors: Imran Hunjra Ahmed , Faisal Farida , Gulshion Faiza
Published: December 2019

This study gauges the impact of cost leadership strategy and financial management controls on financial performance of firms in Pakistan’s services sector. Drawing on a sample of banking, insurance and investment firms listed on the Karachi Stock Exchange, we find that cost leadership strategy and financial management control systems have a significant and positive impact on financial performance. This implies that both factors should be aligned in the long term.
Relationship between Service Quality, Customer Loyalty and Customer Satisfaction
Authors: Mahmood Atif , Tauheed Rana Muhammad Luqman , Kanwal Sara
Published: December 2019

This study examined the influence of service quality on customer loyalty, and aimed to determine if this relationship was mediated by customer satisfaction. Data were gathered from customers of eight banks in Pakistan through an adapted self-administered questionnaire. Respondents were selected using convenience sampling. The distributed questionnaire was based on a modified SERVQUAL model.479 complete survey responses were returned out of a total of 700 distributed. The completed questionnaires were examined through descriptive statistics, regression analysis, and PROCESS technique (Hayes2013). Results revealed a significant effect of service quality on customer loyalty. Customer satisfaction was found to have a significant mediating effect on the relationship between service quality and customer loyalty. The outcomes of our study could be useful for policy-making in bank management, and future banking expansion. There is additional generalized benefit to having insight into customers’ thinking regarding the banking sector.
Are forum networks social networks? A methodological perspective
Authors: Poquet Sasha , Tupikina Liubov , Santolini Marc
Published: December 2019

The mission of learning analytics (LA) is to improve learner experiences using the insights from digitally collected learner data. While some areas of LA are maturing, this is not consistent across all LA specialisations. For instance, LA for social learning lack validated approaches to account for the effects of cross-course variability in learner behavior. Although the associations between network structure and learning outcomes have been examined in the context of online forums, it remains unclear whether such associations represent bona fide social effects, or merely reflect heterogeneity in individual posting behavior, leading to seemingly complex but artefactual social network structures. We argue that to start addressing this issue, posting activity should be explicitly included and modelled in forum network representations. To gain insight to what extent learner degree and edge weight are merely derivatives of learner activity, we construct random models that control for the level of posting and post properties, such as popularity and thread hierarchy level. Analysis of forum networks in twenty online courses presented in this paper demonstrates that individual posting behavior is highly predictive of both the breadth (degree) and frequency (strength) in forum communication networks. This implies that, in the context of forum-based modelling, degree and frequency may not reflect the social dynamics. However, results suggest that clustering of the network structure is not a derivative of individual posting behaviour. Hence, weighted local clustering coefficient may be a better proxy for social relationships. The empirical results are relevant to scientists interested in social interactions and learner networks in digital learning, and more generally to researchers interested in deriving informative social network models from online forums.
PKM USAHA KECIL DI KAWASAN BUKIT KASIH KANONANG MINAHASA
Authors: Kumaat Robby Joan , Rotinsulu Debby Ch. , Engka Daisy S. M.
Published: December 2019

Usaha Kecil adalah usaha yang berskala kecil, memiliki modal kecil dan cakupan pasar yang kecil pula. Keterbatasan modal dan cakupan pasar merupakan hal yang lumrah karena dalam perjalanan untuk menjadi besar butuh proses dan waktu. Keterbatasan Modal yang dimiliki merupakan kendala utama untuk pengembangan usaha. Begitu juga dengan Usaha Kecil yang ada di Kawasan Bukit Kasih Kanonang Minahasa. Keterbatasan Modal merupakan masalah dari Mitra Usaha kecil yang ada di Kawasan Bukit Kasih Kanonang, serta keterbatasan SDM dalam mengakses permodalan lewat Perbankan dengan penyusunan Proposal Kredit Usaha. Metode PKM ini yakni Penyuluhan untuk meningkatkan pengetahuan dan Pemahaman dari mitra tentang Pentingnya Permodalan dalam pengembangan usaha,Mengkakses modal dari pihak Perbankan  serta pelatihan pembuatan proposal kredit usaha dengan khalayak sasaran mitra PKM yakni usaha kecil di kawasan Bukit Kasih Kanonang. Target Luaran yang dihasilkan berupa peningkatan pengetahuan dan pemahaman mitra PKM, serta Publikasi Artikel dalam jurnal Ilmiah, dan berita media online.
PELATIHAN KEWIRAUSAHAAN WANITA KAUM IBU DAN PEMUDA REMAJA PUTRI JEMAAT GPKdI KELURAHAN PANIKI DUA KECAMATAN MAPANGET KOTA MANADO PROVINSI SULAWESI UTARA
Authors: Rumawas Wehelmina
Published: December 2019

Kaum perempuan lebih khusus kaum ibu dan remaja putri memiliki peran dan potensi strategis dalam pembangunan. Karena itu program pemberdayaan sangat penting untuk dilakukan. Tujuan kegiatan program kemitraan masyarakat (PKM) pada wanita kaum ibu dan remaja putrid Jemaat GPKdI Paniki Dua ini adalah untuk memberikan pengetahuan dan pemahaman tentang kewirausahaan serta menumbuhkan mental atau jiwa berwirausaha. Pelatihan ini juga untuk memotivasi mitra agar dapat memanfaatkan hasil sumber daya alam yang ada disekitar. Hasil kegiatan ini terjadi peningkatan pengetahuan dan pemahaman tentang kewirausahaan serta semangat untuk menjadi wirausahawan.
PERAN PEREMPUAN DALAM PENCEGAHAN STUNTING DI KECAMATAN BUNAKEN KOTA MANADO PROVINSI SULAWESI UTARA
Authors: Timban Jean Fanny Junita , Tangkere Ellen Grace , Lumingkewas Jelly Ribka Danaly
Published: December 2019

Stunting in under-five children is a reduced growth rate primarily caused by chronic undernutrition that leads to a child having height much less than is normal for age. This condition manifests mostly after two years old. The definition of stunting according to the World Health Organization (WHO) is for the "height for age" value to be less than two standard deviations of the WHO Child Growth Standards median. Indonesia has been plagued recently with stunting. In 2015, the World Bank indicates that stunting has cost 3 to 11 percent of the gross domestic product. Previous research works have documented that mothers play an important role in preventing stunting through antenatal care and child nursing. The objective of this study is to explore the role played by the mothers in Bunaken, Manado, in antenatal care and child nursing that prevent stunting. Samples are drawn using purposive sampling and data are analysis descriptively. The results show that the mothers’ roles include taking antenatal check up to four times during pregnancy, daily use of FE 90 pill, participating in pregnancy counseling and care, delivery by health professionals, attending integrated service post (posyandu), visiting health professionals for postnatal care, completing universal immunization on child over 12 months old, and participating in educational activities for under-five nursing and nutritional fulfillment at least once a month. Of these eight recorded roles, however, there are merely 20% mothers indicate they regularly taking part in pregnancy counseling and care. Furthermore, only one percent (n = 3) respondents that report they attending educational activities for under-five nursing and nutritional fulfillment.
PENINGKATAN KAPASITAS PENGELOLAAN BADAN USAHA MILIK DESA (BUMDES) DI DESA KOKA DAN DESA KEMBES 2 KECAMATAN TOMBULU
Authors: Lumintang Juliana , Waani Fonny Jeane
Published: December 2019

Bumdes in Koka and Kembes 2 villages have carried out activities with simple organizing and types of activities that did not go well. The initial capital of Bumdes was not developed and the types of activities were stagnant. The problem is, the management of the activities of Village-Owned Enterprises (Bumdes) in Koka and Kembes Dua Villages, has not run well in accordance with Bumdes management rules issued by the Minister of Villages and Disadvantaged Regions No. 4 of 2015, the business planning process and business feasibility analysis not done so that the selection of business types is done carelessly. The solution that has been implemented is to strengthen the management of the Bumdes to the Bumdes management and village officials so that the government and the Bumdes management will learn about the importance of correct Bumdes management by conducting business planning and business feasibility analysis. The method used is lecture and Focus Group Discusion (FGD) mapping of potential and Bumdes business type selection.
PERILAKU APARATUR SIPIL NEGARA DALAM MEMBERIKAN PELAYANAN PRIMA (EXCELLENT SERVICE) PADA DINAS PENANAMAN MODAL DAN PELAYANAN TERPADU SATU PINTU KOTA KENDARI
Authors: Amir Muhammad , Hairani Idrus Sitti , Ardot Ardot
Published: December 2019

This study aims to determine and describe the behaviour of the State Civil Apparatus in providing services and describing the Implementation of Excellent Services at the One-stop Investment and Integrated Services Office of Kendari City. The research method used is descriptive qualitative research, a description of the results of interview observations and documentation studies, so as to be able to describe various matters relating to the Behavior of State Civil Apparatuses in Providing Excellent Service. The results showed that the behaviour of the State Civil Apparatus in providing Prime services in terms of the dimensions of receiving, responding, respecting and being responsible for providing services to service users had gone quite well, but the implementation was not optimal because there were still found several employees who had not shown behaviour and good treatment to the community. Implementation of excellent service in terms of dimensions of service procedures, service costs, completion time, service products, facilities, infrastructure, competency of service providers as a whole is good
Autonomous Data hiding in an Encrypted Image using KM-DH Algorithm
Authors:   Computer Science and Engineering, St.Joseph’s College Of Engineering, Chennai, India., Janani* S. , Shalini M. ,   Computer Science and Engineering, St.Joseph’s College Of Engineering, Chennai, India., Parkavi K. ,   Computer Science and Engineering, St.Joseph’s College Of Engineering, Chennai, India, Chandrasekar A. ,   Computer Science and Engineering, St.Joseph’s College Of Engineering, Chennai, India.
Published: January 2020

K Means Clustering (KM) based data hiding algorithm (KM-DH) is to perform cluster operation which means split pixels into chunks from already encrypted image. Under Consideration of splitted pixels find place to allocate information Authenticated person encrypt the image pixels with their key to prepare envelope image then flow goes by grouping the pixels to stuff the already encrypted image of lowest bits to generate place to allocate data using K means Clustering methods with the help of secret key it form split up matrix.In Receiver side after getting the encrypted data they can withdraw data and image separately without overlapping each other using data and image encryption key.At the same time receiver can also get both the image and data without any bug by dimensional link.
Increasing Coverage with Efficiency in WSN using Energy Efficient Algorithms
Authors:   CSE, Koneru Lakshmaiah Education Foundation ,Vijaywada, India., Dongaonkar* Ms.Shabda , Srinivasu Dr. Nulaka ,   CSE, Koneru Lakshmaiah Education Foundation ,Vijaywada, India., Adsul Dr.Alpana ,   IT, SITS, Narhe,Pune,India.
Published: January 2020

Current years Wireless Sensor networks is a leading area in research due to its number of applications in massive areas .The major concern for Wireless sensor networks is an issue of power of batteries for sensor nodes , several algorithms were transcribed to solve this problem but in so many cases only energy efficiency is considered , coverage problem with energy efficiency is not addressed in most of the cases. To give a better solution for energy efficiency and coverage in this paper modified LEACH protocol is proposed with genetic algorithm, which gives comparatively better results than EBRP protocol.
Methods of Communications and Political Empowerment of BSP in Uttar Pradesh
Authors:   Ph.D., Department of Mass Communications, Telangana University, Nizamabad, Telangana, India., Bade* Shrikanth
Published: January 2020

This study attempts to examine the reach and effectiveness of communication channels used by BSP party in Uttar Pradesh. Hoardings, Banners, posters, road signs, slogans, SMS, advertisement and graffiti’s’ are some of the example of media used by the political parties for their communication. At the same time the message that is conveyed through the channels is important. BSP had been working intensely on its slogan of “Bahujan Hitaya Bahujan Sukhaya” since its inception. It has attempted to portray itself as a party which is for politically empowering the Scheduled Casts, Scheduled Tribes, the OBCs and other minorities. This research will investigate the earlier communication strategies that gave thumping success to the BSP, the current complacency that has set in and also the future possibilities in improving communication through usage of social media. Before carrying the full-fledged study a pilot study was carried. This article presents the pilot study in brief.
Classification and Functional Analysis of Major Plant Disease using Various Classifiers in Leaf Images
Authors:   Research scholar in Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai. She is currently Utility Analyst at Fidelity National Information Services, Durham, NC, USA, Gangadharan* Kapilya , Kumari G. Rosilne Nesa ,   Professor in the Department of Computer Science and Engineering, in Shadan women’s college of Engineering and Technology, Chennai, India, Dhanasekaran D. ,   Professor in the Department of Computer Science and Engineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, India
Published: January 2020

Plant disease interrupts the normal or Ordinary condition of a plant and it alters the essential functionality of a plant. Which intern impacts the productivity of the crop. Speedy observation, recognition and categorization of the plant pathogens will increase the crop yield more than 60% of the total productivity. Disease analysis is more evident on the leaves when compare to the other parts of the plants. Automated methods are most commonly available in different image processing techniques to detect the pathogen attack which can be made more efficient by combining multiple domain, that utilizes computer vision technologies. Most modern techniques or technologies are analyzed to identify the various disease on several crops or crop types. The paper summarizes about types of plants, types of plant diseases and the standard methodologies or technique that would help gaining knowledge about Computer Vision and its applications on plant disease identification and classification. Performance of the Classifiers are analyzed to recognize and classify the better method that typically works among different plant groups and different types of pathogen attack.
Effect of Audit Opinion, Company Size, Financial Distress and Return on Assets on Auditor Switching
Authors:   Accounting Department, Faculty of Economics and Communication, Bina Nusantara University, Jakarta, Indonesia, Handoko* Bambang Leo , Haryanto Felix ,   Accounting Department, Faculty of Economics and Communication, Bina Nusantara University, Jakarta, Indonesia
Published: January 2020

Every company that goes public or has already listed on the stock exchange must first be audited financial statements before publishing. Auditors who audit often change, both mandatory and voluntary. The researcher wants to know what causes the company to make auditor changes. This study aims to determine the effect of audit opinion, company size, financial distress and return on assets for auditor switching. This study conducted on manufacturing companies listed in Indonesia Stock Exchange period year 2015-2017. A total of 36 manufacturing companies are used as sample by using the purposive sampling method. Data analysis technique used is logistic regression analysis with SPSS version 25. Auditor switching is measured by the switch of audit partner. The result concluded that audit opinion effect on auditor switching, whereas the company size, financial distress and return on assets have no effect on auditor switching.
Methods and Means of Implementing Technology of Personality-Oriented Training of a Vocational Training Teacher
Authors:   Minin Nizhny Novgorod State Pedagogical University, Nizhny Novgorod, Russian Federation., Vaganova* O.I. , Tsyganova L.V. ,   Togliatti State University, Tolyatti, Russian Federation., Gorbunova N.V. ,   VI Vernadsky Crimea Federal University Yalta, Russia, Republic of Crimea, Simferopol, Bulaeva M.N. ,   Minin Nizhny Novgorod State Pedagogical University, Nizhny Novgorod, Russian Federation, Lapshova A.V. ,   Minin Nizhny Novgorod State Pedagogical University, Nizhny Novgorod, Russian Federation
Published: January 2020

The implementation of personality-oriented learning technology in modern training of a teacher in vocational training plays a significant role, since the central figure in the process of developing a modern competent specialist is the value of individual, taking into account his individual qualities and needs. Therefore, the aim of the article is to identify methods and tools implemented in the process of using technology of personality-oriented learning, contributing to development of a competent graduate. The article demonstrates the role of personality-oriented learning, reveals the essence of technology of personality-oriented learning. The functions of personality-oriented learning and mechanisms of its implementation are reflected and the importance of the counseling role of the teacher in educational process is noted. Among the methods used in the framework of personality-oriented learning, methods of problem-based learning, the brainstorming method, discussions, game forms and methods, the project method, etc. are noted. These methods contribute to the active development of education content by students and contribute to their inclusion in design and research activities which provides not only their knowledge and skill development, but also creative thinking development, self-improvement abilities, and professional competencies acquisition.