bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between Cheiloscopic Patterns and ABO Blood Groups among South Indian Population
Authors: Potdar Shrudha , Sudeep CB , Khanapure Sneha , Suhas HG , Arjun MR
Published: August 2017

Background

Human beings have few characteristics that are unique from others. Lip prints are one of such feature. They are not changed throughout the life and are not influenced by injuries, diseases, or environmental changes. According to the various antigen–antibody reactions in the bloodstream, different individuals have specific blood groups.

Aim

To study the distribution of lip print patterns among individuals with different ABO and Rh blood groups and also to know the relation between their characters and blood groups.

Materials and methods

In the present study, lip prints were collected randomly from 85 individuals, and their blood group matching was performed. This is to identify the most common lip print type and to know any association between lip print types and blood groups. Tsuchihashi's classification of lip prints was used to compare with the ABO and Rh blood grouping systems.

Results

It was observed that in individuals with B+, A+, and O− blood groups, predominant pattern was Type IV and individuals having blood group O+ and AB+ common lip print pattern was Type II.

Conclusion

This study showed strong association between lip print patterns and ABO blood groups as some blood groups were not included in statistical analysis; further studies including larger sample are essential to substantiate the results.

Clinical significance

Correlating lip print with blood group helps in identification of the suspects. Along with lip prints, another biological record that remains unchanged throughout the lifetime of a person is the blood group. Determining the blood group of a person from the samples obtained at the site of crime and also recovering lip prints from site can help identify a person.

How to cite this article

Khanapure S, Suhas HG, Potdar S, Sam G, Sudeep CB, Arjun MR. Association between Cheiloscopic Patterns and ABO Blood Groups among South Indian Population. J Contemp Dent Pract 2017;18(7):596-600.
A Cross-sectional Community-based Study on Healthcare seeking Behavior of Elderly Women for Urogenital Symptoms
Authors: Padhi MM
Published: August 2017

Introduction

Sociological literature indicates gender differentiation in both health status and use of health services. It has been observed that women did not complain of any medical problem until it started interfering with their daily activities. Therefore, a cross-sectional community-based survey was conducted in lower socioeconomic group areas of Delhi to document the health care-seeking behavior of elderly women for urogenital symptoms and also to explore the reasons that influence them.

Aim and objective

The study aimed at documenting the health care-seeking behavior of elderly women belonging to lower socioeconomic group for urogenital symptoms and also to improve their health care-seeking behavior by using information education and communication (IEC) and behavior change communication (BCC) strategy.

Materials and methods

Stratified random sampling technique was applied for selection of 5 zones out of the 12 Municipal Corporation of Delhi (MCD) zones. The zones were selected according to their size by using probability proportional to size sampling. The list of colonies was taken from the website of MCD. Then an equal number of 20 colonies from this list was selected by simple random sampling from each of the five zones. From these 100 colonies, a total of 824 women aged 50 years and above were identified through snowball sampling and were interviewed with the help of an interviewer administered questionnaire.

Results

Analysis of responses of representative sample of 824 women aged 50 and above in statistically selected low socioeconomic areas of National Capital Territory of Delhi revealed that 479 (58.1%) of the women were found to be suffering from urogenital problems. From these 479 women who suffered from urogenital problems, nearly 271 (56.6%) did not report the problem to their family members and 262 (54.8%) did not report it to doctors.

Conclusion

Based on the results of this survey, it was concluded that many elderly women do not report about their urogenital symptoms neither to their family members nor to doctors for various reasons. Therefore, the women should be made aware about the existence of effective screening and health care facilities for their problems. They should be educated about the ways to prevent these problems. The IEC and BCC strategies should be used in the lower socioeconomic group areas to improve the health care-seeking behavior of elderly women for urogenital symptoms. Steps should be taken to improve the accessibility and affordability of the services.

How to cite this article

Bhat S, Yadav B, Singhal R, Srikanth N, Padhi MM, Singh R, Dhiman KS. A Cross-sectional Community-based Study on Healthcare seeking Behavior of Elderly Women for Urogenital Symptoms. J Res Ayurvedic Sci 2017;1(1):34-39.
Herbal Recipes used by traditional healers towards Reproductive and Urinary healthcare in Wayanad (Kerala) India.
Authors: Dilipkumar EK , Janardhana GR , Abhijith M.
Published: August 2017

The traditional healers in Wayanad (Kerala), India possess rich aboriginal herbal medicinal knowledge (AHMK). This investigation has brought in to light many valuable therapeutic measures which were at the verge of extinction. Validation and documentation of some of such valuable in formation was hence done in order to conserve at least a part of this aboriginal ethno medicinal heritage. The study consists of three consecutive phases. In the first phase a methodology for the study including work plan was elucidated. A field level testing of the method was executed at a selected study site. In the second phase an extensive data collection cum field appraisal long three calendar years commences from July 2010 to July 2013 was conducted. In the final and third phase, validation and recording of the valid responses was done. A total of 60 species distributed in 56 genera belong to 38 families were identified being used in 67 recipes meant for 15 reproductive and urinary healthcare measures in Wayanad (Kerala), India. 31 herbs, 28 trees, 22 climbers and 16 shrubs were among the medicinal constituents.  The therapeutic ingredients includes  Fresh whole plants (12), dried whole plant (08), fresh root (2), dry root (29), fresh tuber (01), dried tuber (17), fresh bark (01), dried bark (02), fresh leaves (04) dried leaf (01), dried stem (01), dried petiole (01), pith powder (01),  dried gum (2), fresh inflorescence (01),  dried inflorescence (01), fresh flower (03),  dried stamen (01), dried fruits (07),  dried seeds (11), and seed oil (01).  Validity stands maximum when FPVS was four and minimum when FPVS was two. Among the 67 medicinal recipes 59 has highest FPVS and the remaining 08 has mediocre FPVS. Many of the aboriginal herbal medicinal cultures (AHMC) and the associated therapeutic knowledge and practices still alive in the district are at the verge of extinction. The present study hence pivots around the conservation issues of this aboriginal medicinal heritage, particularly in the cure and management of urinary and reproductive ailments. This improves and sustains the aboriginal therapeutic system to contribute better to the national health repository.

 
Composition and Biological Activities of different Date Seed varieties (Phoenix dactylifera) of Oman: Cultivation Zone Influence
Authors: Rehman Najeeb Ur , Hussain Hidayat , Al-Broumi Mohammed Abdullah , Khiat Mohammed , Csuk René , Al-Rawahi Ahmed , Khan Abdul Latif , Mabood Fazal , Green Ivan R , Al-Harrasi Ahmed
Published: August 2017

Date (Phoenix dactylifera L.) seeds (pits) account for ca. 10% of the date fruit and it is the date pits that present a major problem to the date palm industry in the USA as a waste product. Currently  date pits are employed as a food source for animals and poultry, as a soil fertilizer and also as a road base gravel In order to understand the varietal effects of Omani date seeds on the nutritional properties of dates and to explore the use of this waste product from the food industry, twenty two native date seeds (Phoenix dactylifera L.) including the varieties; Qushbu Narenjahn, Fardh, Naghal, Manhi, Qush Balquan, Helali Oman, Khasab, Seedi, Qush Jabrin, Khalas, Qush Basrah, Qushbu Maan, Handal, Khunaizi, Qush Mamoor, Barshi, Barni, Azad, Zabad, Qush Tabak, Qush LuLu, and Halali Alhasa were collected from six regions of the Sultanate of Oman and were examined for their nutritional value, antioxidant and urease properties. Energy values, dry matter, and carbohydrate level were the predominant components examined in the date seeds , followed by fiber, moisture, along with small amounts of ash, protein, and fat. The results of the 22 varieties of date seeds showed a significant energy value of between 283.0 to 407.9 kcal/100g, dry matter of between 93.3%-96.3%, carbohydrate content of between 43.8%-80.6%, moisture in the range of 4.3%-6.6%), fat in the range of  5.0%-10.9%, ash content of between 0.73%-1.08%, protein content of 0.2%-6.9% and fiber content of between 5.0%-32.5%. Furthermore the antioxidant potential ranged between 7.4 - 88.3% depending upon the type of date seeds and location of samples. In this regard the Handal date seeds collected from Al-Hamra showed the highest antioxidant potential with 88.3% inhibition. Similarly urease inhibition ranged from 0.94-70.3% and Qush Tabak date seeds collected from Al-Hamra demonstrated the highest urease potential with 70.3% inhibition. It is noteworthy that Qush Basrah, Seedi, Qush Balquan, and Handal date seeds have significantly higher nutritional attributes compared to the rest in the study group. Moreover Fardh, Khasab, Khalas, and Handal date seeds collected from more than one region of Oman showed variation in some nutritional values. The nutritional analysis further demonstrated the correlation of proximate parameters in different regions of Oman. Results of the current investigation indicate a promising and significant potential for date seeds to be used as a supplementary source of a healthy diet as well as in specific pharmaceutical applications.
Phytochemical Screening and Biological Studies of Shilajit (Asphaltum)
Authors: Aziz Shahid , Khaliq Sidra , Ur-Rehman Habib , Ghani Kh. Shakeel , Irshad Muhammad , Green Ivan R , Hussain Hidayat
Published: August 2017

Shilajit (asphaltum)  is produced  by the long term humification  of dead plant material  and organic vegetable matter  by different micro-organisms and has great potential for the treatment of a variety of human conditions.  This treatise reviews its origin, sources, chemical composition, biological  and  commercial importance. Phytochemical analysis was done by standard methods to evaluate  different Shilajit (asphaltum) classes of compounds in different samples of shilajit  which are responsible for their  biological activity.  Shilajit`s anti-microbial activity has been evaluated  against four different bacterial strains viz., Escherichia coli, Psuedomonas aeuroginosa, Klebisella pneumonia and Staphylococcus aureus. Phytochemical analysis illustrated  that shilajit contains  terpenoids, cardiac glycosides, saponins and reducing sugars. Surprisingly,  some classes of compounds are absent in shilajit  viz., alkaloids, flavonoids, tannins and anthraquinones. . Shilajit showed no response towards halophytic bacteria and  negligible activity was shown towards other strains of bacteria. Since   anti-microbial activity is based on environmental factors  its activity varied  between locations.
Proximate composition, antioxidant activities and phenolic composition of Cucumis sativus forma hardwickii (Royle) W. J. de Wilde & Duyfjes
Authors: Attar Usmangani A , Ghane Savaliram G
Published: August 2017

In the present investigation, nutritional, anti-nutritional and antioxidant potential of Cucumis sativus forma hardwickii was evaluated for the first time. The results revealed that leaf and fruit of Cucumis sativus f. hardwickii were rich source of ash, carbohydrate, fat, fibre and proteins. In addition, appreciable amounts of Vitamin C and E were also observed. Considerable antinutritional factors in leaf and fruit were noted which can be reduced by different processing methods. In sequential solvent extraction, methanol found to be the best in the extraction of antioxidants, which was supported with the highest antioxidant activities. Among all ¬¬the extracts, it was noted that leaves extracted with methanol had higher amount of phenols and flavonoids than fruit. In addition, the potent radical scavengers mainly phenolics were detected using RP-HPLC where tannic acid, gallic acid and hydroxybenzoic acid were also quantified in leaf and fruit. Superior antioxidant potential may be due to the presence of other bioactive compounds present in fruit. Additional research on bioactive properties of this plant is needed to explore this neglected wild cucumber for nutraceutical purpose and as a functional food.
Pharmacological Evaluation and Antifertility Activity of Aloe barbadensis Linn on female wistar rats.
Authors: Shah Sunil Kumar , Jhade Deenanath , Chouksey Rajendra
Published: August 2017

Ethanolic and Aqueous extract of Leaf of Aloe barbadensiswas study, antifertility activity in proven fertile female Wistar Rats at the doses 500mg/kg b.wt./day for 30 days. Different parameters were studied in female wistar rats including effect of Reproductive outcome, Anti-implantation, Abortifacient study and Estrogenic and Anti-estrogenic activity, Phytochemical were observed.,Aloe vera Leaves shown positive test for Alkaloids, Steroid, Flavonoids, Terpene, Carbohydrates and Tannin. The extract of Aloe vera has anti-fertility effect the control rats showed good number of litters. Treatment of animal with different extracts, resulted a significant (P< 0.05, P< 0.01). antifertility activity (42.2% and 7.8%) was exhibited by AAV and WAV respectively. After 21 days of the extracts free period, the antifertility effect of the extracts was reversed. The extract treatments with AAV, an increase in the resorption index (%) by the extract is an indication of failure in the development of the embryo. The mean percentage of anti-implantation and percent resorption (abortifacient) were found to be highest for AAV-29.46%, WAV -12.17, and AAV-32.96%, WAV-7.78% respectively. The decrement in implantation caused by the extracts may be due to estrogenic or anti-estrogenic activity. However, along with standard AAVexhibiting more potent estrogenic and less potent anti-estrogenic when compared with standard.Clinical assessment of Female antifertility agents should include acceptability, safety and efficacy during and after the treatment. The present study was therefore carried out to evaluate the claimed antifertility effect of Aloe veraleaf using different aspects of reproductive physiology in female wistar rats.
The radical scavenging activity of 2-2’ diphenyl -1- picrylhydrazil (DPPH) on the methanol extracts and Ethyl acetate fractions of red dragon fruit peel (Hylocereus polyrhizus (F.A.C.Weber) Britton dan Rose)

Authors: Wahdaningsih Sri , Wahyuono Subagus , Riyanto Sugeng , Murwanti Retno
Published: August 2017

 

Red dragon fruit (H. Polyrhizus) is one of the the plants that has a great potential as natural antioxidant. This study tested the activity of radical scavenging of 2-2' diphenyl -1- pikril hidrazil (DPPH) in the methanol extract, as well as in the soluble and insoluble fractions of ethyl acetate of red dragon fruit peel. This research is carried out through various stages, such as: extraction and fractionation to obtain both insoluble fraction and soluble fractions of ethyl acetate. Antioxidant activity test is conducted by the method of thin layer chromatography and spectrophotometry. Antioxidant activity test, IC50 values of methanol extract, ethyl acetate soluble fraction, and insoluble fraction of ethyl acetate had been obtained consecutively as much as 241.19 µg /mL, 8.34  µg/mL, 46.84 µg/mL. The soluble fraction of ethyl acetate had greater antioxidant activity compared to the methanol extract and the insoluble fractions of ethyl acetate.
Protective role of Bacopa monnieri against Rotenone- induced Parkinson’s disease in PC 12 cell lines
Authors: Swathi Gunduluru , Ramaiah Chintha Venkata , Rajendra Wudayagiri
Published: August 2017

 Parkinson disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopaminergic (DA) neurons in the substantia nigra, decreased striatal dopamine (DA) levels, and consequent extrapyramidal motor dysfunction. PC 12 cells originate from pheochromocytoma cells of rat adrenal medulla and share many common characteristics with substantia nigra cells. They produce DA, several growth factors, such as nerve growth factor, fibroblast growth factor and transforming growth factor, and express DA receptors. Hence, these cells are being used to study the alterations in dopaminergic neurons, in vitro, that occur during Parkinson’s disease. Since long term usage of antiparkinsonian drugs cause high incidence of pharmacoresistence and untoward side effects, attention has been paid in recent years to screen bioactive compounds from natural medicinal plants for treatment of several neurological disorders including Parkinson’s disease. Keeping in view of relative importance of natural medicinal plants, the present study is mainly focused to characterize the anti-parkinsonian effect of Bacopa monnieri (BM), an Indian herb which is being extensively used in Ayurveda treatments related to neurological complications. The present study was designed to assess the neurotoxicity of rotenone on DA-producing PC12 cells and explore the possible antiparkinsonian effect of BM in comparing with Levodopa (LD) (Reference control). The survivability studies of PC 12 cell-lines were analysed using MTT assay. Pre-treatment with BM extract significantly ameliorated morphological damage, cell viability, and apoptosis of PC12 cells exposed to RT. Hence BM extract can be effectively used in the treatment of PD and other related neurological disorders.
In-vitro antioxidant, Xanthine oxidase-inhibitory and in-vivo Anti-inflammatory, analgesic, antipyretic activity of Onopordum acanthium
Authors: Habibatni Sofiane , Zohra Abdessalam Fatma , Khalida Hani , Anwar Sirajudheen , Mansi Iman , Awadh Ali Nasser A
Published: August 2017

Onopordum acanthium (Scotch thistle) belong to Asteraceae (Compositae). O. acanthium is a flowering biennial plant native to Europe and Western Asia with coarse spiny leaves 20-50 cm in width with conspicuous and spiny-winged stems. We have previously reported pro-apoptotic and cytotoxic effect of Onopordum acanthium crude extract against glioblastoma U-373 cells. The present study was designed to evaluate the cytotoxicity, antioxidant, xanthine oxidase inhibition, anti-inflammatory, analgesic, antipyretic activity of butanolic extract of Onopordum acanthium. Cytotoxicity of different solvent (methanolic, butanol, chloroform and petroleum ether) extract studied by brine shrimp lethality bioassay, total flavonoid and phenolic, antioxidant, xanthine oxidase inhibition activity was studied by in-vitro whereas anti- inflammation studied by carrageenan-induced paw edema model, antipyretic with 20 % brew yeast injection induced pyretic model, analgesic with 1 % acetic acid induced analgesic model investigated in in-vivo in wistar rats. Good antioxidant activity was found with IC50 = 134.4 µg/ml with considerable amount of total phenolic and flavonoid content. Xanthine oxidase inhibition effect was weak with IC50 = 572.9 µg/ml. Oral administration of O. Acanthium butanolic extract (OA) showed minimum lethality of brine shrimp nauplii henceforth OA butanolic phases was selected for further in-vivo studies. OA 200 and 400 mg/kg body weight decreased the oedema by 37.78 % and 40.52 %, respectively; standard aspirin 100 mg/kg decreased 42.62 % at 5th hour of Carrageenan injection.  OA 200 and 400 mg/kg significantly decreased acetic acid-induced abdominal writhes when compared to standard aspirin. OA have shown dose and time dependent decrease in body temperature in yeast induced pyrexia, comparable to standard, aspirin. The present results demonstrate that OA has notable anti-inflammatory, antipyretic, analgesic activity related to presence of phenolic compounds as from literature it has been demonstrated that isolated compounds from aerial parts of Onopordum acanthium had strong activity in in-vitro assay.  
Estrogenic and anxiolytic effects of the decoction of stem bark of Khaya anthotheca (Welw.) C.DC (Meliaceae) in ovariectomised Wistar rats
Authors: Ketcha Wanda Germain Jean Magloire , ZEMO GAMO Franklin , DJIOGUE Sefirin , AWOUNFACK Charline Florence , NJAMEN Dieudonne
Published: August 2017

Khaya anthotheca (Welw.) C.DC (Meliaceae) is a plant used in Cameroon to alleviate vaginal dryness in postmenopausal women and is also known to have anxiolytic properties.This work was designed to evaluate estrogen-like effects of this plant on primary estrogens targets of ovariectomized adult rats, as well as to evaluate its anxiolytic activities in the elevated plus-maze (EPM) test. In the 3-day uterotrophic assay, the extract increased (p < 0.01) the size of the vaginal epithelia and stimulated the acini differentiation of the mammary gland. In the EPM test, the extract increased the percentage of number of entries (p <0.05; p <0.01) and the percentage of time spent (p < 0.05) into open arms.Italso induced a decrease in percentage of number of entries (p < 0.05; p < 0.01) and the percentage of time spent (p < 0.05) into closed arms. The extract also induced an increase of total arms entries (p < 0.05; p < 0.01) and rearing (p < 0.05). Moreover, there was a decrease of defecation and grooming (p < 0.05; p < 0.01). These results suggest that K. anthotheca is endowed with estrogenic and anxiolytic properties, likely due to the presence of some estrogen-like compounds.
Hibiscus noldea (Malvaceae) Aqueous Extract Prevents Insulin Resistance and Protects Pancreatic Islets From Dexamethasone Damages in Rat.
Authors: Florence Ngueguim Tsofack , Jean Philippe Djientcheu Tientcheu , Hubert Donfack Jean , Raceline Gounoue Kamkumo , Paul Desire Dzeufiet Djomeni , Pierre Kamtchouing , Theophile Dimo
Published: August 2017

Hibiscus noldea leaves-stems aqueous extract is used in Cameroonian traditional medecine to manage diabetes. To investigate the preventive effect of Hibiscus noldea aqueous extract on dexamethasone-induced insulin resistance, the animals received one of the following treatments: distilled water (10 mL/kg), metformine (200 mg/kg), or H. noldea (100 or 200 mg/kg) concomitantly with dexamethasone (0.5 mg/kg, ip) for ten days. Body weight was evaluated daily and blood glucose levels were measured. At the end of experiment, insulin sensitivity test was performed and lipid profile, transaminases Aspartate amino transferase, Alanin amino transferase, malondialdehyde, superoxide dismutase, catalase, and reduced glutathione were evaluated. Histological analysis of the liver was investigated to estimate glycogen content using Periodic Acid Schiff coloration and histomorphometry of pancreatic islets area was performed.

The administration of dexamethasone during ten days induced body weight loss, hyperglycaemia, insulinresistance, an imbalance in lipid profile, an increase in transaminases and oxidative stress. Dexamethasone treatment also induced an increase in the pancreatic islets area and depletion in the levels of hepatic glycogen. Concomitant administration of dexamethasone and the aqueous plant extract prevented the rise in blood glucose levels, reduced insulinresistance, improved lipid profile and oxidative status. The aqueous extract of H. noldea prevented the use of glycogen storage and the increase in pancreatic islet area in dose dependent manner.

Conclusion: The stem leaves aqueous extract from Hibiscus noldea have the ability to reduce insulinresistance via its antihyperglycaemic, hypolipidemic and antioxidant activities. These results justify the use of this extract in the management of diabetic state.
Role of protective Pelargonium Sidoides root extract and Curcumin on Mushroom poisoning: An Experimental study in rats
Authors: Unsal Velid , EB Kurutaş , M Güngör , Emrah Aksan M
Published: August 2017

Phalloidin is a cyclic heptapeptide containing cysteine amino acids. The toxicity of phallodin is attributed to the sulfur atom of the sulfur in the indole ring of the molecule and it is responsible for acute gastroenteritis occurring during the initial period of poisoning. Pelargonium sidoides, reinforcing the immune system, antiviral, has antibacterial properties as well as antioxidant properties.The aim of this study is to investigate the protective role of Pelargonium sidoides and Curcumin against mushroom poisoning.

28 Wistar albino rats were divided into four groups. Group I; Along the study, 0.2  ml saline was administered intraperitoneally to the rats .Group II (phalloidin, 0.5 mg / kg) were administered for 5 days of study. Group III : From the beginning to the end of the study, 0.5  mg / kg phalloidin i.p.,0,2 ml/kg pelargonium sidoides were administered orally. Group IV : From the beginning to the end of the study, 0.5 mg / kg phalloidin intraperitoneally,0.2 ml/kg Curcumin were administered orally.At the end of the study, the rats were sacrificed. The blood of the rats was taken. İn serum Superoxide dismutase (SOD), Glutathione peroxidase (GSH-Px), Paraxonase (PON), Arylesterase (ARE) ,Adenosine Deaminase (ADA) , Xhanthine oxidase (XO),Protein Karbonyl (PC), Malondialdehyde(MDA), Nitric oxide (NO),  were measured by spectrophotometry.

In Group II, MDA, , PC levels and XO activity increased significantly compared to Group I. (p<0.05).PS and Curcumin treatment ameliorated some enzyme levels (SOD, GSH-px, PON, ADA ) in serum with  phalloidin induced rats. Values of Group III approached Group I.

Phalloidin increases toxic ROS. Pelargonium sidoides and Curcumin  are  antioxidant, antitoxic. And They such as silibin  can protective against mushroom poisoning.

 
Oxidative stress and inflammation caused by n-Hexyl salicylate in mouse skin: the effectiveness of flavonoids
Authors: Orsolic Nada , Balta Vedran , Odeh Dyana , Mataković Maja , Skurić Jadranka
Published: August 2017

Reactive oxygen species (ROS) play a role in a numbered of degenerative conditions including psoriasis. Psoriasis is a chronic inflammatory disease who’s the etiopathogenesis is not yet completely understood, and therefore there is no standardized therapeutical approach. Flavonoids, recognized as potent antioxidants, are multifunctional molecules that can act as anti-inflammatory and antiproliferative agents through the modulation of multiple signaling pathways. The present study was designed to investigate the protective role of flavonoids [quercetin, chrysin, curcumin or Epigallocatechin 3-gallate (EGCG)] against n-Hexyl salicylate (HXS)-induced oxidative stress and inflammation in skin. Anti-oxidative and anti-inflammatory effect of flavonoids is quantified by histopathological assessment of skin, measuring the levels of lipid peroxidation and glutathione (GSH) in the skin, total number of inflammatory cells in peritoneal cavity, macrophage spreading index, and hematological and biochemical parameters.

Topically applied of n-Hexyl salicylate caused significant increase in lipid peroxidation and decrease in GSH, which is accompanied by an increase total number of inflammatory cells in skin and peritoneal cavity, functional activity of macrophages, and enzymatic activity of ALP and AST. In contrast, topically applied 5 % preparation of flavonoids (quercetin, chrysin, curcumin or EGCG) with HXS effectively prevented these alterations and maintained the antioxidant status.

The results suggest that flavonoid preparations can serve as a potent antioxidant and anti-inflammatory agents in psoriatic-like skin lesions, without toxic effects.
Oral supplementations of Bauhinia variegata’s leaf extract has anxiolytic effect and improves locomotory and exploratory behavior of female albino mice
Authors: Iqbal Furhan , Jahangir Muhammad , Ullah Asmat , Khan Khattak Muhammad Naseer , Iqbal Shahid
Published: August 2017

Present study was designed to investigate the effects of 200 mg/ml solvent/Kg of body weight of Bauhinia variegata’s leaf extract on neuromuscular coordination, locomotory and exploratory behavior of adult female albino mice. Six week old female albino mice were used as experimental animals. Mice were either orally supplemented with 200 mg/ml/Kg of body weight Bauhinia variegata’s leaf extract or with saline solution [0.9%] for 7 days. Behavioral observations were made by applying a series of neurological tests [Rota rod, Elevated plus maze, Light and dark box, Open field and Novel object test]. Exploratory and locomotory behavior during Open Field test was improved in leaf extract treated mice as they had more means speed [P = 0.01], rotations [P = 0.001], clockwise rotations [P = 0.004] and anti-clockwise rotations [P = 0.001] than control mice. Bauhinia variegata’s leaf extract treated mice had higher transition frequency [P = 0.002] and spent more time in light compartment during light dark box test than saline treated controls. Bauhinia variegata’s leaf extract treated mice covered more distance [P = 0.033] with higher speed [P = 0.028] compared to control mice during Elevated Plus Maze test. Bauhinia variegata’s leaf extract improves the locomotory and exploratory behavior in adult female albino mice. Leaf extract of Bauhinia variegate can be further explored to be used as a therapeutic agent for the treatment of neurological ailments.
Anti-leukemic activity of phosphoproteins from Sesamin via induction of nuclear antigen H731and CLIP-associating protein 2 isoform X25 mediated apoptosis
Authors: Wannapruk Pattharin , Paemanee Atchara , Roytrakul Sittiruk , Tanyong Dalina I
Published: August 2017

Leukemia is an uncontrolled proliferation hematopoietic cancer cells that commonly treats with conventional therapies such as chemotherapy. However, many side effects were reported. Alternative medicines have been developed by using natural or herb compounds as therapeutic drug. Sesamin, a class of phytoestrogen isolated from sesame seed displaying potent anticancer activity in vitro and in vivo.However, the mechanism by which sesamin mediates anticancer effects on leukemic cells are notfully understood. In thisstudy, the effects of sesamin on cell viability, cell apoptosis and expression of phosphoproteins in Molt-4 and NB4 leukemic cell lines were investigated using MTT assay, flow cytometry and immobilized metal affinity chromatography (IMAC) phosphoprotein enrichment and LC-MS, respectively. The results showed that sesamin reduced viability and induced apoptosis in leukemic cells. In addition, 79 phosphoproteins were identified from LC-MS within three main clusters including biological regulation, cellular processand metabolic process. Interestingly, nuclear antigen H731 (PDCD4) and CLIP-associating protein 2 isoform X25 (CLASP2) showed increased in sesamin treated cells and associated protein-ligand interaction network with allicin, capsaicin, cucurbitacin B, and rapamycin which are known to activate apoptosis in cancer cells.Then, sesamin could be developed as candidate of alternative leukemia treatment  in the future.
Evaluation of hepatoprotective effect of Waltheria indica against various NSAIDs-induced hepatic damage in rats
Authors: Chandekar Amol , Upamanyu Neeraj , Vyas Amber , Tripathi Atul , Agrawal Surendra , Jhade Deenanath
Published: August 2017

The objective of the present study was to evaluate methanolic extract of leaves of Waltheria indica linn. for hepatoprotective potency of the potent solvent extract. The hepatotoxicity was induced by diclofenac, carbon tetrachloride (CCl 4 ) and acetaminophen. In CCl 4 induced hepatotoxicity study, animals were divided into five groups (n=6). Methanolic extract of Waltheria indica (WIM) groups were injected in doses of 400 mg/kg and 600mg/kg body weight along with CCl 4 and Silymarin 100mg/kg was taken as standard drug. Similarly procedure was followed in diclofenac and acetaminophen induced hepatotoxicity. Blood samples and liver were collected and liver hisopathological studies were carried out. These histopathological analysis suggested that WIM extract have the ability to reduce the degree of hepatic fibrosis induced by various factors. And concluded that WIM extract has significant hepatoprotective activity thus this study scientifically support the theory to use of this plant in traditional medicine for the treatment of liver disorders.
Sodium silicate mediated response of antioxidative defense system in Lycopersicon esculentum mill. under water stress
Authors: Malhotra Chanchal , Kapoor Riti Thapar , Ganjewala Deepak , Singh NB
Published: August 2017

The present study was designed to study the effect of water stress on Lycopersicon esculentum Mill. and role of sodium silicate in the protection of tomato plants under water deficit condition.

Different biochemical parameters such as photosynthetic pigments, protein, sugar, MDA content, proline, nitrate reductase activity and activities of antioxidant enzymes (SOD, CAT, APX and POX) were examined in tomato leaves at 40 and 60 DAS by the standard methods. The lycopene and β-carotene contentsin tomato fruits were also analyzed at 60, 65 and 70 DAS.

Water stress significantly decreased relative water content (RWC), pigment content, sugar and protein contents in tomato leaves at 60 DAS but the accumulation of proline was stimulated in tomato leaves under water deficit condition. The activities of antioxidant enzymes such as SOD, CAT, APX and POX were significantly increased under (3d and 6d) water stress condition at 60 DAS.
This study offers first hand information on the water stress-induced oxidative stress in Lycopersicon esculentumand development of antioxidative defense system against drought.The results obtained clearly indicated the positive impact of sodium silicate in protection of tomato plants under water deficit condition.
Cryptocurrencies and their potential for large-crowd, cost-effective transactions in peer production
Authors: Kow Yong Ming
Published: August 2017

Cryptocurrencies — being digitally transmitted and embodied within peer-to-peer infrastructures — may mediate new forms of peer-driven interactions and collaborations among Internet users. In this paper, I performed in-depth interviews of cryptocurrencies’ emerging uses with 16 participants between September 2013 and March 2015. My analysis of how these users have used cryptocurrencies revealed a new feature, large-crowd, cost-effective transactions (trades involving massive numbers of participants), that can drive trades involving massive numbers of participants. Cryptocurrencies, having a peer-driven logical infrastructure, are already known to offer a freer alternate medium for users to customize or automate monetary processes. But the newly identified feature makes it possible for peer producers to organize work payment options involving a large crowd of contributors. This capacity suggests the emergence of many-to-many financial flows in small individual amounts. Taken together, I identify a cluster of temporal and spatial ways that cryptocurrencies remix and automate payment mechanisms and pathways.
Public attention, social media, and the Edward Snowden saga
Authors: Park Yong Jin , Jang S. Mo
Published: August 2017

Although prior research indicated the power of social media in drawing attention to particular issues, little research explored precise patterns by which an issue sustains its salience in mediated social platforms. We dissected the issue-attention cycle of Snowden revelations over a one-year period. We tackled this, using real-time large-scale Twitter data, and found that social media attention varied dramatically over time by the specificities of issue. Volumes of attention associated with — instead of being independent from — traditional media mention of the issues. Directions for future studies as well as implications for using social media for civil rights issues are addressed.
An Overview of RNA-seq Data Analysis
Authors: Ferdous Tahsin , Ullah Mohammad Ohid
Published: August 2017

Latest breakthrough in high-throughput DNA sequencing have been launched different arenas for transcriptome analyses, jointly named RNA-seq (RNA-sequencing). It exposes the existence and amount of RNA in a biotic sample at a specific time by utilizing next generation sequencing (NGS). In this review, we aimed to explore the several methods which are applied in analyzing RNA-seq data. We also discussed its importance over microarray data. As establishment of several methods have already taken place to analyze RNA-seq data, therefore, further analysis is very essential to select the best one to avoid false positive outcomes.
Analyzing the Effectiveness of Vocabulary Knowledge Scale on Learning and Enhancing Vocabulary through Extensive Reading
Authors: Iqbal Syeda Asima , Komal Syeda Anila
Published: August 2017

This research is about the effectiveness of Vocabulary Knowledge Scale after extensive reading which helps in the enhancement of global language skills especially their vocabulary. This research is an endeavor to create an awareness of its significance in language acquisition through extensive reading especially focusing on vocabulary. The Vocabulary Knowledge Scale and interviews were the data collection tools. On the basis of analysis and interpretation, it was understood that Vocabulary Knowledge Scale was helpful in measuring vocabulary of the students and showed improvement in their vocabulary. This research also exposed many weaknesses of the administration and teachers. Further, it became clear that at the moment the problem was of insufficient training of teachers to motivate their students and be the best role models. Administration and teachers both need to show willingness to motivate students to develop reading habits.
Beyond P values and Hypothesis Testing: Using the Minimum Bayes Factor to Teach Statistical Inference in Undergraduate Introductory Statistics Courses
Authors: Page Robert , Satake Eiki
Published: August 2017

While interest in Bayesian statistics has been growing in statistics education, the treatment of the topic is still inadequate in both textbooks and the classroom. Because so many fields of study lead to careers that involve a decision-making process requiring an understanding of Bayesian methods, it is becoming increasingly clear that Bayesian methods should be included in classes that cover the P value and Hypothesis Testing. We discuss several fallacies associated with the P value and Hypothesis Testing, including why Fisher’s P value and Neyman-Pearson’s Hypothesis Tests are incompatible with each other and cannot be combined to answer the question “What is the probability of the truth of one’s belief based on the evidence?” We go on to explain how the Minimum Bayes Factor can be used as an alternative to frequentist methods, and why the Bayesian approach results in more accurate, credible, and relevant test results when measuring the strength of the evidence. We conclude that educators must realize the importance of teaching the correct interpretation of Fisher’s P value and its alternative, the Bayesian approach, to students in an introductory statistics course.
Strategic Actions to Environmental Changes: Act Ahead or React Upon?
Authors: Lee Jai Joon , Bach Seung B.
Published: August 2017

This study investigates how firms proactively or reactively launch (Venkatraman & Prescott, 1990) their strategic actions in response to environmental changes, particularly to deregulatory and technological changes. Strategic initiatives including mergers and acquisitions to deal with firms’ uncertain competitive environments have been regarded as key strategic actions. This study analyzes the nature of firms’ willingness to take strategic actions in response to the key environmental changes in the telecom service industry. The natures of environmental changes, broadly defined as deregulatory and technological changes in this research’s domain, trigger firms to take on strategic actions both proactively and reactively.
Women Fertility Decision using the Count Model in Malaysia
Authors: Kamaruddin Rohana
Published: August 2017

Fertility depends on household decisions in Malaysia; and, in turn, these decisions are strongly influenced by economic and socio-economic factors. Currently, fertility levels around the world vary according to the intergenerational relationships, the socio-economics statuses, and the socio-demographic characteristics of a particular nation. In general, more industrialized and economically developed societies have lower fertility than less-developed societies do. Groups that are more educated and earn higher incomes have lower fertility than less-educated groups with lower incomes do. The purpose of this paper is to dicuss the development of the empirical model to identify the principal determinants of fertility in Malaysia. The results stemmed from the use of panel data that is obtained from the Minnesota Population Centre, the Integrated Public Use Microdata Series, and international data provided by the Department of Statistics, Malaysia. In the empirical analysis, count models are employed. The findings show that marital status, owning a house, and households having women of child-bearing age all affect fertility decisions. In addition, social characteristics, such as ethnicity, religion, socio-economic status, and education level, affect household’s fertility decision.
The Human Security Dimension of China’s Belt and Road Initiative
Authors: Dellios Rosita , Ferguson R. James
Published: August 2017

Despite the geopolitical calculations associated with China’s Belt and Road Initiative, and how this will allow Beijing greater influence in transregional relations, the human security dimension goes to the heart of China’s wider regional strategy. The importance of development cannot be understated even as the “rise of China” attracts the headlines. How well Beijing can engage wider human security concerns will be crucial for the success of this megaproject. It is argued that the human security aspect of China’s Belt and Road Initiative requires a stronger ethical base—one which draws on China’s own Confucian heritage. This allows for both cultural inclusiveness and the promotion of higher levels of trust towards Beijing’s policies and intentions.
THE APTUS™ HELI-FX™ ENDOANCHOR™ SYSTEM – THE INNOVATIVE ENDOVASCULAR REPAIR METHOD FOR THE PATIENT WITH POSTEVAR TYPE IA ENDOLEAK
Authors: Muszyński Tomasz , Polak Karina , Krzywoń Julia , Zbierska-Rubinkiewicz Katarzyna , Kwiatkowski Tomasz , Trystuła Mariusz
Published: August 2017

[b]Background:[/b] The aim of our study was to present an innovative endovascular technique – the Aptus™ Heli-FX™ EndoAnchor™ system com bined with the Endurant Stent Graft cuff used as a method of choice for the patient in a very poor general condition with symptomatic abdominal aneurysm and a post-EVAR type IA endoleak.[b]Case study: [/b]An 85-year-old male patient, was operated on in March 2016 with endovascular aneurysm repair (EVAR) of a 9.3 cm in diameter ruptured abdominal aneurysm (RAA), accompanied by disturbance to the coagulation profile (prolonged INR of 3.3 because of anticoagulant treatment with Rivaroxaban due to atrial fibrillation). 9 months later, he developed a severe abdominal pain and was urgently referred to the Vascular Surgery Department, at the John Paul II Hospital, Kraków. The Angio-CT xamination revealed the type IA and II endoleaks and a recurrence of the rupture symptoms. He was successfully operated on using an innovative endovascular repair system, the Aptus™ Heli-FX™ ndoAnchor™ system with a combination of other endovascular procedures, such as Endurant Stent Graft cuff implantation. [b]Conclusions:[/b]The innovative endovascular repair system, Aptus™ Heli-FX™ EndoAnchor™ together with the Endurant Stent Graft cuff was successfully used in the treatment of the patient. This technique prevented him from developing serious complications or even death and gave him a much better quality of life in comparison with open surgery repair.
THE DYNAMICS OF COGNITIVE FUNCTIONING IN THE PROCESS OF PREPARING A CONTESTANT FOR A TRIATHLON. A CASE STUDY WITH THE USE OF THE AUTHOR’S NEUROPSYCHOLOGICAL SUPPORT PROGRAM
Authors: Bidzan-Bluma Ilona , Pielak Marek , Budnik-Przybylska Dagmara
Published: August 2017

[b]Background: [/b]The aim of the research project was to prepare a person who does not do much sport and has never taken part in a triathlon, to become a contestant in Ironman, i.e., swim for 3.86 km (2.4 miles), ride a bike for 180.2 km (112 miles) and run for 42.195 km (26.2 miles – the marathon distance). The preparatory period was from January 2015 to June 2016. The author’s neuropsychological training program was applied. It consists of exercises increasing attention span, enhancing episodic and spatial memory. [b]Material/ Methods:[/b]The authors of the project assumed that three Ironman disciplines, i.e., swimming, cycling and running, should be enriched with two additional modules which would ensure the optimum training of the contestant: psychological training and diet. All this should be supported by biological regeneration and relaxation. For the first three months the future contestant was exercising his attention and taking part in relaxation sessions once a week. For the subsequent six months the frequency of the former increased to two times a week, and the latter – three times a week. [b]Results: [/b]It was found that the neuropsychological training program was effective; already after half a year from the implementation of the training plans, the contestant improved the scope of memorized material significantly, enhanced the level of attention focus and achieved a higher level of visualisation when imagining himself in a relaxing place; meanwhile, a lower level of attention focus was observed when he was visualising swimming, which may indicate that this activity was automated. [b]Conclusions: [/b]Multidimensional preparation for a sporting competition, including neuropsychological training, was effective for an increased level of attention focus and visual-spatial memory improved visualization skills, the ability to relax quickly and effectively, and the ability to enter the flow state were effective for our sportsman.