bluuebunny/crossref_metadata_2025 huggingface dataset:
Pre-service teachers’ Perceived Concerns and Benefits during Practicum
Authors: Pekoz Bayram
Published: February 2020

The study focused on pre-service teachers’ benefits from teaching practice, and the problems they experienced during practicum. Using document analysis method, the data were obtained from their portfolios which included self-evaluation forms, weekly journal entries, and summary reports of their teaching experience. The results indicate that a) teaching practice is a turning point for pre-service teachers, b) it was the practicum opportunity rather than the coordinating teachers’ support that mattered, c) selection of the coordinating  teachers was not done effectively, d) longer-service coordinating teachers followed conventional methods, e) the more practical the university courses the less problems the pre-service teachers experienced.
PHOTO-DEGRADATION OF 5 – FLUOROURACIL. COMPARATIVE STUDY ON THE EFFICIENCIES OF UV/H2O2, UV/TIO2, UV/H2O2/TIO2 PROCESSES
Authors: Constantin Mirela Alina , Constantin Lucian Alexandru , Nitoi Ines , Cristea Ionut , Boulac Ellea
Published: February 2020

Degradation experiments on 5-Fluorouracil synthetic solutions were performed using three types of advanced oxidation systems: UV/H2O2, UV/TiO2 and UV/H2O2/TiO2. Optimum parameters for all three systems were established and 5-Fluorouracil degradation efficiencies were calculated, for all systems being more than 97%. The results showed that the combined UV/H2O2/TiO2 system is offering shortest irradiation time, the possibility to recover and reuse the photo catalyst as well as the possibility to use solar radiation. Obtained results proved also that advanced oxidation processes represent a viable option for degradation of hazardous pollutants that cannot be removed properly via conventional wastewater treatment processes.
Is Galanin a Promising Therapeutic Resource for Neural and Nonneural Diseases?
Authors: Oliveira Volpe Caroline Maria , Vaz Tatiana , Rocha-Silva Fabiana , Villar-Delfino Pedro Henrique , Nogueira-Machado José Augusto
Published: February 2020

Background:

Galanin (GAL) constitutes a family of neuropeptides composed of four peptides:
(i) galanin (GAL), (ii) galanin-message associated peptide (GAMP), (iii) galanin-like peptide
(GALP), and (iv) alarin. GAL contains 29/30 amino acids, and its biological action occurs through the
interactions with its various receptors (GALR1, GALR2, and GALR3). The neuropeptide GAL regulates
several physiological and pathophysiological functions in the central nervous system, the peripheral
nervous system, and the peripheral organs. GAL is secreted mainly by oligodendrocytes, astrocytes, and
the gastrointestinal tract, and its effect depends on the interaction with its different receptors. These receptors
are expressed mainly in the central, peripheral nervous systems and the intestines.

Objective:

The present review evaluates the role of GAL family in inflammatory diseases. An overview
is given of the signaling and pharmacological effects due to the interaction between GAL and
GALR in different cell types. The potential use of GAL as a therapeutic resource is critically discussed.

Conclusion:

GAL is suggested to have an anti-inflammatory function in some situations and a proinflammatory
function in others. The literature on GAL is controversial and currently not conclusive.
This could be due to the complexity of the metabolic network signaling induced by the interactions between
GAL and GALR. In the next future, GAL might be a promising therapeutic resource for several
diseases, but its practical use for disease control is presently not advisable.
Analysis of Vpr Genetic Variations between Chinese Major Circulating Recombinants CRF01_AE and CRF07_BC
Authors: Du Ling , Wang Lina , Yu Tong , Xin Ruolei , Meng Zhefeng
Published: February 2020

Background:

HIV-1 CRF01_AE and CRF07_BC recombinant strains are responsible for
more than 80% of new infections in China since the beginning of the 2000s. These two strains may
have distinct genetic mutations, which resulted in distinct patterns of pathogenesis related to the viral
gene, Vpr.

Objective:

The amino acid pattern and genetic diversity of Vpr were analyzed and characterized in
HIV-1 CRF01_AE and CRF07_BC HIV-1 strains.

Methods:

The Vpr gene was amplified from extracted viral RNA and DNA sequencing was performed
using an ABI3730 analyzer. The positional amino acid composition, genetic variation and
distance of Vpr sequence were analyzed by Bio-Edit 7.2 and Mega 6.01 software packages.

Results:

A total of 162 CRF01_AE and 80 CRF07_BC derived Vpr sequences were obtained by
DNA sequencing. CRF01_AE patients showed higher viral load and lower CD4 counts than
CRF07_BC patients (P<0.05). Higher genetic distance and more polymorphic amino acids were
found in CRF01_AE Vpr than CRF07_BC Vpr (P<0.05). The common conservative amino acid region
was identified as 29EAVRHFP35 in both CRF07_BC and CRF01_AE. Of note, the R77Q mutation
was found in both the most recently Chinese derived CRF07_BC and CRF01_AE Vpr.

Conclusion:

CRF01_AE derived Vpr has higher genetic variation and pathogenesis in comparison
to the CRF07_BC strain.
Beyond Promoter: The Role of Macrophage in Invasion and Progression of Renal Cell Carcinoma
Authors: Zhang Haibao , Zhu Guodong
Published: February 2020

Renal cell carcinoma (RCC) is one of the common urologic neoplasms, and its incidence has
been increasing over the past several decades; however, its pathogenesis is still unknown up to now.
Recent studies have found that in addition to tumor cells, other cells in the tumor microenvironment
also affect the biological behavior of the tumor. Among them, macrophages exist in a large amount in
tumor microenvironment, and they are generally considered to play a key role in promoting tumorigenesis.
Therefore, we summarized the recent researches on macrophage in the invasiveness and progression
of RCC in latest years, and we also introduced and discussed many studies about macrophage
in RCC to promote angiogenesis by changing tumor microenvironment and inhibit immune response in
order to activate tumor progression. Moreover, macrophage interactes with various cytokines to promote
tumor proliferation, invasion and metastasis, and it also promotes tumor stem cell formation and
induces drug resistance in the progression of RCC. The highlight of this review is to make a summary
of the roles of macrophage in the invasion and progression of RCC; at the same time to raise some
potential and possible targets for future RCC therapy.
Exploring the Protective Effect of ShenQi Compound on Skeletal Muscle in Diabetic Macrovasculopathy Mice
Authors: Duan Yuhong , Gao Hong , Su Hongxia , Liu Aixia , Liu Ya , Yuan Haipo , Xie Chunguang
Published: February 2020

Objective:

ShenQi compound (SQC) is a traditional herbal formula, which has been used to
treat Type 2 diabetes mellitus (T2DM) and complications for years. The aim of this study was to explore
the preventive and protective effects of SQC recipe on the skeletal muscle of diabetic macrovasculopathy
mice, which provides a theoretical basis for the clinical use of this formula.

Methods:

We evaluated the effect of SQC in a diabetic vasculopathy mouse model by detecting a series
of blood indicators (blood glucose, lipids and insulin) and performing histological observations.
Meanwhile, we explored the molecular mechanism of SQC treatment on skeletal muscle by genome
expression profiles.

Results:

The results indicated that SQC could effectively improve blood glucose, serum lipids (total
cholesterol (TC), Triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density
lipoprotein cholesterol (LDL-C)) and insulin (INS) levels in diabetic vasculopathy mice, as well as
alleviating skeletal muscle tissue damage for diabetic macrovasculopathy. Meanwhile, compared with
rosiglitazone, SQC showed a better effect on blood glucose fluctuation. Moreover, the gene microarray
analysis indicated that SQC might improve T2DM by affecting biological functions related to cell
death and cell adhesion. Moreover, 7 genes (Celsr2, Rilpl1, Dlx6as, 2010004M13Rik, Anapc13,
Gm6097, Ddx39b) might be potential therapeutic targets of SQC.

Conclusion:

All these results indicate that SQC is an effective preventive and protective drug for
skeletal muscle in diabetic macrovasculopathy, and could alleviate skeletal muscle tissue damage
through affecting biological functions related to cell death and cell adhesion.
Accentuate the Positive: Strengths-Based Therapy for Adolescents
Authors: Yuen Eunice , Sadhu Julie , Pfeffer Cynthia , Sarvet Barry , Daily R. Susan , Dowben Jonathan , Jackson Kamilah , Schowalter John , Shapiro Theodore , Stubbe Dorothy
Published: February 2020

Purpose:

The field of psychiatry has conventionally employed a medical model in
which mental health disorders are diagnosed and treated. However, the evidence is amassing
that using a strengths-based approach that promotes wellness by engaging the patient’s assets
and interests may work in synergy with the medical model to promote recovery. This harmonizes
with the patient-centered care model that has been promoted by the Institute of Medicine.

Methods:

The article uses a clinical case to highlight the attributes of a strength-based model
in the psychiatric treatment of adolescents.

Results:

Outcome metrics from a number of studies have demonstrated enhanced youth and
parent satisfaction and decreased use of hospital level of care with the implementation of
strengths-based therapeutic modalities.

Implications:

Incorporating strengths-based interventions into conventional psychiatric practice
provides a multi-faceted treatment approach that promotes recovery in children and adolescents
with psychiatric disorders.
Enhanced Pharmacokinetic Activity of Zotepine via Nanostructured Lipid Carrier System in Wistar Rats for Oral Application
Authors: Tirumalesh Cernam , Suram Dinesh , Dudhipala Narendar , Banala Nagaraj
Published: February 2020

Background:

Zotepine (ZT) is a substituted dibenzothiepine tricyclic molecule
and second generation antipsychotic drug. It is available as the parenteral and oral solid
dosage form, but, orally administered ZT has a poor oral bioavailability (10%) that might
be due to either poor water solubility, high lipophilicity (Log P 4) and also first-pass hepatic
metabolism.

Objective:

The oral bioavailability of ZT was improved by loading into a nanostructured
lipid carriers (NLCs) system.

Methods:

Hot homogenization with probe sonication method was used for the preparation
of ZT-NLCs formulations and characterized for an optimal system based on physicochemical
characteristics and in vitro release. Differential scanning calorimetry (DSC), X-ray diffraction
(XRD) analysis, and scanning electron microscopy (SEM) studies were used to
confirm the crystalline nature and shape of the optimized ZT-NLC formulation. The physical
stability of the optimized ZT-NLC formulation was evaluated at the refrigerator and
room temperature over two months. Furthermore, in vivo pharmacokinetic (PK) studies of
optimized ZT-NLC and ZT coarse suspension (ZT-CS) as control formulation, were conducted
in male Wistar rats.

Results:

The optimized formulation of ZT-NLC showed Z-avg, PDI, ZP of 145.8 ± 2.5 nm,
0.18 ± 0.05, -31.6 ± 1.8 mV, respectively. In vitro release studies indicated the sustained
release of ZT. DSC and XRD studies revealed the conversion of ZT into an amorphous
form. SEM studies showed the spherical shape of the ZT-NLC formulation. PK studies
showed 1.8-folds improvement (p<0.05) in oral bioavailability when compared with ZTCS
formulation.

Conclusion:

Overall, the results established that NLCs could be used as a new alternative
delivery vehicle for the oral delivery of ZT.
Cropmarks in het Tiberdal: onderzoek naar gebruik en bewoning van de Tibervallei nabij Crustumerium in de Romeinse tijd
Authors: Trienen Tom , Attema Peter
Published: February 2020

Cropmarks in the Tiber valley: research into the use and occupation of the Tiber valley near Crustumerium in Roman times. This paper reports on a short field campaign aimed at investigating an extensive crop-mark identified in aerial photography by the first author. The cropmark is situated in the Tiber floodplain near the ancient settlement of Crustumerium, north of the centre of Rome and close to old riverbanks of the river Tiber. Surface finds, coring and geophysical mapping suggest that the cropmark indicates the buried remains of a substantial building complex of probably Roman Imperial date. This is an important discovery, which contributes to our understanding of the palaeogeography, sedimentation regime and settlement history of the Tiber floodplain. In this paper we limit ourselves to an initial (and speculative) interpretation of the cropmark in terms of its extent and individual components. The fieldwork was carried out in the framework of the Crustumerium project of the Groningen Institute of Archaeology, in collaboration with the Archaeological Superintendency of Rome.
Een vondst van groot belang: de boot van Britsum (Fr.)
Authors: Nieuwhof Annet , van Holk André
Published: February 2020

A find of great importance: the boat of Britsum.

In 1906, a boat, or at least ship’s timbers, were unearthed during commercial quarrying of the terp (dwelling mound) of Britsum (province of Fryslân/Friesland). It was recently found that a number of fragments have survived; they are stored in the Northern Archaeological Depot at Nuis. Since finds of vessels and ship’s timbers in the formerly maritime landscape of the northern Netherlands are extremely rare, and knowledge about ships and seafaring in this area is limited, these fragments have been thoroughly examined. A sample was radiocarbon-dated, with an outcome of 1246 ± 15BP, 685-778 calAD, a period with hardly any finds of ship’s timbers in the Netherlands. The two fragments that were examined were frames: a knee and a v-shaped floor timber of a flat-bottomed vessel. Their shape shows that this may have been a boat with two pointed ends, in Dutch a punter. Since part of this boat may still be hidden in the remainder of the terp of Britsum, further investigation of this site is recommended.
La Torretta della Bufalotta: stille getuige van een verdwenen landschap
Authors: Bronkhorst Remco , Seubers Jorn
Published: February 2020

La Torretta della Bufalotta: silent witness to a lost landscape. In the 1890s, the Dominican Father Peter Paul Mackey located the remains of the protohistoric settlement of Crustumerium, on a small hill ca. 15 km north of Rome crowned by picturesque ruins, amongst which the medieval so-called Torretta (tower) della Bufalotta. His identification was close yet incorrect. As was shown in the 1970s, Crustumerium lay some 450 m to the northwest. In this article, we delve into the remains of this torretta – which in fact was never a tower – and its surrounding surface materials which, taken together, testify to a complicated history spanning more than 2000 years.
Van boerderij naar klooster naar weeshuis. De gebruiksplanten op het terrein van de Roode Weeshuisstraat, Groningen
Authors: van Rijn Morvenna , Vrede Frits
Published: February 2020

From farm to monastery to orphanage. The use plants on the grounds of the Roode Weeshuisstraat, Groningen. This paper focuses on the analysis of plant remains that were recovered from the archaeological excavations at the Roode Weeshuisstraat, in the city of Groningen (province of Groningen), which took place in 1990 and 1991. The excavation results revealed three different phases of occupation: early medieval farms, a late medieval monastery and an early-modern orphanage. Botanical samples were taken from different contexts belonging to these different phases in order to examine the diet of the different types of inhabitants (farmers, nuns and orphans).
Tracking Knowledge Evolution in Cloud Health Care Research: Knowledge Map and Common Word Analysis
Authors: Gu Dongxiao , Yang Xuejie , Deng Shuyuan , Liang Changyong , Wang Xiaoyu , Wu Jiao , Guo Jingjing
Published: February 2020

Background

With the continuous development of the internet and the explosive growth in data, big data technology has emerged. With its ongoing development and application, cloud computing technology provides better data storage and analysis. The development of cloud health care provides a more convenient and effective solution for health. Studying the evolution of knowledge and research hotspots in the field of cloud health care is increasingly important for medical informatics. Scholars in the medical informatics community need to understand the extent of the evolution of and possible trends in cloud health care research to inform their future research.

Objective

Drawing on the cloud health care literature, this study aimed to describe the development and evolution of research themes in cloud health care through a knowledge map and common word analysis.

Methods

A total of 2878 articles about cloud health care was retrieved from the Web of Science database. We used cybermetrics to analyze and visualize the keywords in these articles. We created a knowledge map to show the evolution of cloud health care research. We used co-word analysis to identify the hotspots and their evolution in cloud health care research.

Results

The evolution and development of cloud health care services are described. In 2007-2009 (Phase I), most scholars used cloud computing in the medical field mainly to reduce costs, and grid computing and cloud computing were the primary technologies. In 2010-2012 (Phase II), the security of cloud systems became of interest to scholars. In 2013-2015 (Phase III), medical informatization enabled big data for health services. In 2016-2017 (Phase IV), machine learning and mobile technologies were introduced to the medical field.

Conclusions

Cloud health care research has been rapidly developing worldwide, and technologies used in cloud health research are simultaneously diverging and becoming smarter. Cloud–based mobile health, cloud–based smart health, and the security of cloud health data and systems are three possible trends in the future development of the cloud health care field.
Blood Uric Acid Prediction With Machine Learning: Model Development and Performance Comparison (Preprint)
Authors: Sampa Masuda Begum , Hossain Md Nazmul , Hoque Md Rakibul , Islam Rafiqul , Yokota Fumihiko , Nishikitani Mariko , Ahmed Ashir
Published: February 2020

BACKGROUND

Uric acid is associated with noncommunicable diseases such as cardiovascular diseases, chronic kidney disease, coronary artery disease, stroke, diabetes, metabolic syndrome, vascular dementia, and hypertension. Therefore, uric acid is considered to be a risk factor for the development of noncommunicable diseases. Most studies on uric acid have been performed in developed countries, and the application of machine-learning approaches in uric acid prediction in developing countries is rare. Different machine-learning algorithms will work differently on different types of data in various diseases; therefore, a different investigation is needed for different types of data to identify the most accurate algorithms. Specifically, no study has yet focused on the urban corporate population in Bangladesh, despite the high risk of developing noncommunicable diseases for this population.

OBJECTIVE

The aim of this study was to develop a model for predicting blood uric acid values based on basic health checkup test results, dietary information, and sociodemographic characteristics using machine-learning algorithms. The prediction of health checkup test measurements can be very helpful to reduce health management costs.

METHODS

Various machine-learning approaches were used in this study because clinical input data are not completely independent and exhibit complex interactions. Conventional statistical models have limitations to consider these complex interactions, whereas machine learning can consider all possible interactions among input data. We used boosted decision tree regression, decision forest regression, Bayesian linear regression, and linear regression to predict personalized blood uric acid based on basic health checkup test results, dietary information, and sociodemographic characteristics. We evaluated the performance of these five widely used machine-learning models using data collected from 271 employees in the Grameen Bank complex of Dhaka, Bangladesh.

RESULTS

The mean uric acid level was 6.63 mg/dL, indicating a borderline result for the majority of the sample (normal range <7.0 mg/dL). Therefore, these individuals should be monitoring their uric acid regularly. The boosted decision tree regression model showed the best performance among the models tested based on the root mean squared error of 0.03, which is also better than that of any previously reported model.

CONCLUSIONS

A uric acid prediction model was developed based on personal characteristics, dietary information, and some basic health checkup measurements. This model will be useful for improving awareness among high-risk individuals and populations, which can help to save medical costs. A future study could include additional features (eg, work stress, daily physical activity, alcohol intake, eating red meat) in improving prediction.
An Interactive Text Messaging Intervention to Improve Adherence to Option B+ Prevention of Mother-to-Child HIV Transmission in Kenya: Cost Analysis (Preprint)
Authors: Chen Yilin , Ronen Keshet , Matemo Daniel , Unger Jennifer A , Kinuthia John , John-Stewart Grace , Levin Carol
Published: February 2020

BACKGROUND

Mobile health (mHealth) approaches offer potentially affordable ways to support the care of HIV-infected patients in overstretched health care systems. However, only few studies have analyzed the costs associated with mHealth solutions for HIV care.

OBJECTIVE

The aim of this study was to estimate the total incremental costs and incremental cost per beneficiary of an interactive SMS text messaging support intervention within a clinical trial.

METHODS

The Mobile WAChX trial (NCT02400671) evaluates an interactive semiautomated SMS text messaging intervention to improve adherence to antiretroviral therapy and retention in care among peripartum women infected with HIV in Kenya to reduce the mother-to-child transmission of HIV. Women were randomized to receive one-way versus two-way SMS text messages. Messages were sent weekly, and these messages included motivational and educational content and visit reminders; two-way messaging enabled prompt consultation with the nurse as needed. Microcosting methods were used to collect resource-use data related to implementing the Mobile WAChX SMS text messaging intervention. At 2 sites (Nairobi and Western Kenya), we conducted semistructured interviews with health personnel to identify startup and recurrent activities by obtaining information on the personnel, supplies, and equipment. Data on expenditures and prices from project expense reports, administrative records, and published government salary data were included to estimate the total incremental costs. Using a public provider perspective, we estimated incremental unit costs per beneficiary and per contact during 2017.

RESULTS

The weighted average annual incremental costs for the two-way SMS text messaging group were US $3725 per facility, US $62 per beneficiary, and US $0.85 per contact to reach 115 beneficiaries. For the one-way SMS text messaging group, the weighted average annual incremental costs were US $2542 per facility, US $41 per beneficiary, and US $0.66 per contact to reach 117 beneficiaries. The largest cost shares were for the personnel: 48.2% (US $1794/US $3725) in two-way and 32.4% (US $825/US $2542) in one-way SMS text messaging groups. Costs associated with software development and communication accounted for 29.9% (US $1872/US $6267) of the costs in both intervention arms (US $1042 vs US $830, respectively).

CONCLUSIONS

Cost information for budgeting and financial planning is relevant for implementing mHealth interventions in national health plans. Given the proportion of costs related to systems development, it is likely that costs per beneficiary will decline with the scale-up of the interventions.
Analisa Penyebaran Potensi Kekeringan Lahan di Kabupaten Rembang
Authors: Swastikasari Martza , Nanulaitta Natania Frislya
Published: February 2020

Kekeringan lahan yang melanda suatu daerah menimbulkan dampak yang besar terhadap produktivitas lahan pertanian. Terjadinya kekeringan ini disebabkan oleh defisit air akibat kurangnya hujan yang jatuh, laju infiltrasi air yang tinggi serta jenis tanaman yang tidak sesuai dengan ketersediaan air.  Untuk meminimalkan dampak yang terjadi akibat kekeringan lahan maka perlu dilakukan antisipasi dengan mengetahui defisit dan surflus air lahan melalui data curah hujan serta kemampuan tanah menahan air (Water Holding Capasity). Oleh sebab itu, dalam penelitian ini penulis mencoba untuk menganalisa penyebaran potensi penyebaran kekeringan di wilayah Kabupaten Rembang Propinsi Jawa Tengah. Parameter yang didapat yaitu interpretasi dari citra satelit lansat 8 (OLI), data statistik Kabupaten Rembang, dan data curah hujan. Didalam penelitian ini juga penulis menggunakan indeks vegetasi NDVI (Normalized Difference Vegetation Index) dan SAVI (Soil-Adjusted Vegetation Index)yang dapat menghasilkan rata-rata luas wilayah potensi kekeringan di masing-masing kecamatan pada Kabupaten Rembang. Land drought that hit a region has a great impact on the productivity of agricultural land. The occurrence of this drought is caused by water deficit due to lack of falling rain, high water infiltration rate and types of plants that are not in accordance with the availability of water. To minimize the impacts caused by land drought, it is necessary to be anticipated by knowing the deficit and land water surfs through rainfall data and the ability of water holding capasity. Therefore in this study the authors try to analyze the spread of potential spread of drought in rembang district of central java province. The parameters obtained are the interpretation of satellite image 8 (OLI), statistical data of Rembang Regency, and rainfall data. In this study, the authors used the NDVI (Normalized Difference Vegetation Index) and SAVI (Soil-Adjusted Vegetation Index) vegetation index which can produce the average of drought potential areas in each sub-district in Rembang district.
Kemampuan Keuangan Daerah dan Kesejahteraan Masyarakat Kabupaten-Kota di Provinsi Jawa Tengah
Authors: Muta'ali Lutfhi
Published: February 2020

Penelitian ini bertujuan untuk mengidentifikasi potensi keuangan daerah dan kesejahteraan masyarakat, serta mencari pola hubungan dan dimensi spasial serta faktor-faktor penentu dan relasi diantara keduanya sebagai dasar perumusan kebijakan.Dengan analisis kuantitatif, hasil penelitian menunjukkan kondisi tingkat kemandirian keuangan yang cukup dengan kesejahteraan masysrakat yang rendah. Alokasi belanja untuk sosial masih sangat rendah (2%) sehingga sulit diharapkan peningkatan kesejahteraan dari keuangan daerah. Hasil analisis varian menunjukkan tingkat perbedaan keuangan daerah dan kesejahteraan masyarakat antara Kabupaten dan Kota dan juga hubungan erat antara indikator keuangan daerah dan kesejahteraan masyarakat. Semakin tinggi keuangan daerah akan diikuti dengan tingginya kesejahteraan masyarakat. Faktor-faktor yang dianggap berpengaruh nyata terhadap kesejahteraan masysrakat adalah penerimaan per penduduk (X1), tingkta kemandirian daerah (X2) dan efektivitas belanja pembangunan (X5). Tipologi daerah mengelompok pada Tipe I (keuangan tinggi, kesejahteraan tinggi) dan IV (keuangan rendah dan kesejahteraan rendah) sebanyak  77% dan dijadikan sebagai dasar penentuan prioritas pembangunan. This research aims to identify the local financial potential and the social welfare, and look for patterns of relationships and spatial dimensions as well as determinants and relations between the two as a basis for policy formulation. With quantitative analysis, the results of the study indicate the condition of sufficient level of financial independence with the welfare of the community low. The allocation of expenditure for social affairs is still very low (2%) so it is difficult to expect an increase in welfare from local finances. The results of the analysis of variance indicate the level of local financial disparity and the welfare of the community between districts and cities and also the close relationship between local financial indicators and social welfare. The higher regional finances will be followed by high social welfare. Factors considered to have a significant effect on social welfare are income per population (X1), regional independence (X2) and the effectiveness of development spending (X5). Regional typologies cluster in Type I (high finance, high welfare) and IV (low finance and low welfare) as much as 77% and serve as a basis for determining development priorities
PERUBAHAN PERMUKIMAN NELAYAN PASCA REKLAMASI PANTAI DI KELURAHAN LETTE, KECAMATAN MARISO MAKASSAR
Authors: Darmansyah Aidi , Sudaryono Sudaryono , Swasto Deva Fosterharoldas
Published: February 2020

Lette is one of the sub-districts in Mariso Subdistrict, Makassar City which has a suburban area and the community has a livelihood as a fisherman. The condition of the Tanjung Bunga coastal and coastal area has undergone a change, which used to be the territorial waters that are now largely transformed into land, this change is due to the ongoing coastal and coastal reclamation process in the area of Tanjung Bunga. To meet the need for urban space, Lette fishermen have no choice but to be relocated from their place of origin to the flats. This study aims to determine the spatial, cultural, socio-economic changes in the fishing settlement of Lette and the factors that drive these changes. This study uses an inductive-qualitative method with a phenomenological approach. The results of the study show that the changes that occur are changes in coastal space, changes in settlement space and the creation of a central business, tourism and entertainment area. Factors driving these changes are changes in fishing boat access and entry, dock circulation, catching areas that are not potential, domestic activities, spatial space utilization, bale-bale culture, informal fishing activities, and new economic space.
Pengaruh Campuran Bahan Bakar Pertalite-Bioetanol Biji Sorghum pada Mesin Bensin
Authors: Sebayang Abdi Hanra , Ibrahim Husin , Dharma Surya , Silitonga Arridina Susan , Ginting Berta Br , Damanik Natalina
Published: February 2020

The depletion of fossil fuels, rising of earth temperatures and declining of air quality are an unavoidable phenomenon today. Bioethanol fuel is one solution to reduce this problem that comes from renewable raw materials. The purpose of this study is to investigate engine performance and exhaust emissions at gasoline engine by using the sorghum seeds bioethanol-pertalite blends with different mixed ratios (10%, 15%, and 20%). The test is performed on a four-stroke gasoline engine without modification. Engine speeds vary from 1000 to 4000 rpm, and properties of the sorghum seeds bioethanol-pertalite blends are measured and analyzed. In addition, engine torque, brake power, brake specific fuel consumption (BSFC) and brake thermal efficiency (BTE) as well as carbon monoxide (CO), hydrocarbon (HC), and nitrogen oxide (NOx) emissions are measured. The results show that BSFC decreased while BTE increased for a fuel blends containing 20% bioethanol at 3500 rpm engine speed, with each maximum value of 246.93 g/kWh and 36.28%. It is also found that CO and HC emissions are lower for the sorghum seeds bioethanol-pertalite blends. Based on the research results, it can be concluded that the sorghum seeds bioethanol-pertalite blends can improve engine performance and reduce exhaust gas emissions. Keywords: bioethanol; pertalite; performance engine; exhaust gas emission; alternatif fuel.
EKSPLORASI KEANEKARAGAMAN HERPETOFAUNNA DI KECAMATAN GIRIMULYO KABUPATEN KULON PROGO YOGYAKARTA
Authors: Qurniawan Tony Febri
Published: February 2020

The research was aimed to reveal and document hereptofauna from Girimulyo District Kulon Progo Regency,Daerah Istimewa Yogyakarta Province. This research was done from November-Desember 2008 and January-April 2009 in four research locations were Girimulyo, Jatimulyo, Giripurwo and Purwosari. The VES (VisualEncounter Survey) method were used and combined with interview method.. A total of 40 species of herpetofaunaare indentified and includes in to 13 family. Among 40 species, only one (Michrohyla achatina) is endemic to Java.The commonest herpetofaunas along all site were Eutropis multifasciata and Hylarana chalconota.
A SUSTAINABLE SUPPLY CHAIN MODEL OF RELATIONSHIP BETWEEN WOOD SUPPLIER AND FURNITURE INDUSTRY IN INDONESIA
Authors: And Shalihuddin Djalal Tandjung Muh. Hisjam Adi Djoko Guritno
Published: February 2020

Wooden furniture industry is an important industry sector in Indonesia, because many people’s welfare relyon this industry sector and the industry has a big social and environmental impacts. Many wooden furnitureindustries in Indonesia, especially in Central Java Province face problems related to the sustainability. The relationbetween wood suppliers and furniture industry is studied in this paper. A sustainable supply chain management (s-SCM) model is proposed as an approach for solutions for the problems. The approach is chosen due to the characteristics of the problems that related to economic, social, and environmental problems. This aim of this paper is to determine how much supply teak wood must be provided by PP to satisfy furniture industry demand, how much production capacity that must be increased and how large forest area that must be planted in order to achieve environmental and social goals without sacrificing economical goals much. Goal programming (GP) is chosen for solving the problems, because the goals are to maximize the total benefit,minimize the total loss and anticipate the conflicts between goals. Numerical trial based on observation in teak wooden furniture industry in Central Java was used to illustrate our findings. Using pareto efficient principle, the model can satisfy all goals that need to be achieved. Numerical results can be used by decision makers in teak wood industry to analyze the trade-off among several set of alternative solutions.
BERMULA DARI MIMPI MEWUJUDKAN INOVASI
Authors: Herliansyah M.K.
Published: February 2020

Kemakmuran suatu bangsa tergantung pada kemampuannya memanfaatkan sumbersumberalam dan mengembangkan serta memproduksi suatu produk. Bahkan kemampuanmengembangkan serta memproduksi suatu produk merupakan komponen terpentingpenentu tingkat kemakmuran ekonomi suatu bangsa. Bukti-bukti telah menunjukkan banyakbangsa-bangsa di dunia yang miskin sumber alam, tetapi memiliki tingkat kemakmuranyang tinggi karena keunggulannya dalam kemampuan mengembangkan serta memproduksiproduk-produk baru dan unggul.
SPECIES COMPOSITION OF AMPHIBIAN IN GUNUNGKELIR STREAM, JATIMULYO VILLAGE, KULON PROGO
Authors: Dan Trijoko Tony Febri Qurniawan
Published: February 2020

Gunungkelir stream is located in Jatimulyo village, western part of Daerah Istimewa Yogyakarta Province.The ecosystem that surrounds Gunungkelir stream looks natural and unpolluted, it is possible for good livingenvironment of amphibians. However, the database about diversity of Amphibians in Gunungkelir stream hasnot been revealed. This research was done to study species diversity, species richness, species composition anddistribution of amphibians in Gunungkelir stream as an effort to support the sustainability of amphibians livefrom extinction. The research was done on January-May 2009, at night. The VES (Visual Encounter Survey)method with line transects 250 m were used. A total 11 species of amphibians from 6 different amphibia familieswere identified. Phrynoidis aspera, Leptobrachium hasseltii and Hylarana chalconota are dominant species. Thehigest percentage of amphibians population was tadpole (38%), followed by male (35%), female (21%), and theleast were juvenile (6%). During the survey, different species of amphibians were observed with their own rangeof spatial distribution.
PERBAIKAN PROSES FERMENTASI BIJI KAKAO KERING DENGAN PENAMBAHAN TETES TEBU, KHAMIR, DAN BAKTERI ASAM ASETAT
Authors: Dan Sri Wedhastri Donny Widianto, Ajeng Dara Pramita,
Published: February 2020

Most of cocoa beans produced by smallholder farmers were non fermented which can be improved by modifiedfermentation processing. This study was aimed to inverstigate the influence of molasses, yeast Saccharomycescerevisiae, and Acetobacter aceti addition on dried cocoa beans fermentation process.Fresh cocoa beans were dried in a glasshouse and its reducing sugar was analyzed before and after drying. Asmall plastic bucket (20 cm diameter and 30 cm height) with aeration holes was used as fermentation vessel. Driedcocoa beans were soaked in distilled water for 4 hours, inoculated with yeast and acetic acid bacteria cultures, andmolasses were added at two different concentration, i.e, 1 and 1.5 times of reducing sugar lost during drying.Reducing sugar, ethanol, titrated acid, population of yeast, and acetic acid bacteria were monitored duringfermentation. After fermentation the beans were sun dried and its pH and degree of fermentation were determinedto assess the bean quality.The results showed that the addition of molasses mostly at the level of 1.5, S. cerevisiae, and A. aceti increasereducing sugar, ethanol, titrated acid, yeast and acetic acid bacteria of fermentation liquid (pulp). The highestpercentage of fermented beans (68.4 %) was achieved by addition of S. cerevisiae, A. aceti, and molasses atthe level 1.5. It is likely that the addition of S. cerevisiae, A. aceti, and molasses could improve fermentationprocessing of dried cocoa bean.
PENGARUH KHLORHEKSIDIN DIGLUKONAT 2% DAN GLISERIN SEBAGAI BAHAN PENCAMPUR KALSIUM HIDROKSIDA TERHADAP SISA KALSIUM HIDROKSIDA PADA SEPERTIGA APIKAL DINDING SALURAN AKAR GIGI
Authors: Widowati Siswomihardjo Emmawati Prawitasari, Diatri Nari Ratih, dan
Published: February 2020

The most widely used intracanal medicament is calcium hydroxide (Ca(OH2). However, the residue ofCa(OH)2 in the root canal must be removed prior to obturation. The residue of Ca(OH)2 in the root canalwalls would result in apical leakage. This is due to the unstable dimension of Ca(OH)2, reduced flowand working time of the sealers, and decreased adhesion of sealers and gutta percha to root canal walls.This study aimed to determine the effect of Ca(OH)2 vehicles and agitation irrigation techniques on theresidue of Ca(OH)2 in the apical third of the root canal walls.Twelve extracted mandibular first premolars were used in this study. The crowns of the teethwere removed at the apical part of cemento enamel junction with a length of 14 mm from the apical.The canals were prepared with a Step Back technique to obtain Master Apical File ( MAF ) # 40. Thespecimens were randomly devided into groups I, the pastes of Ca(OH)2+chlorhexidine digluconate 2%.In groups II, the pastes of Ca (OH)2+ glycerin were applied. Each specimen of the study was sectionedin the sagittal direction, then was photographed under a stereo microscope at 120x magnification. Thepercentages of Ca(OH)2 residue were calculated using UTHSCSA image tool 3 software. Data wereanalyzed using T-test at 95% level of significance.The results revealed that the group of Ca(OH)2+ chlorhexidine digluconate 2% paste showed thelowest number of residual Ca(OH)2.The conclusion of this study was that the vehicles affected the totalresidue of Ca(OH)2.
Consumer Palatability of Beef Muscles From Australian and US Production Systems With or Without Enhancement
Authors: Garmyn Andrea , Garcia Lyda , Spivey Kari S. , Polkinghorne Rod J. , Miller Mark
Published: February 2020

The objective was to assess the consumer (n = 360) palatability and satisfaction of enhanced (7%) and nonenhanced Australian grain-fed, Australian grass-fed, and US grain-fed beef from 2 beef muscles. Strip loin (longissimus lumborum [LL]) and top sirloin butt (gluteus medius [GM]) subprimals were collected from 12 Australian grass-fed, 12 Australian grain-fed, and 12 US grain-fed (USDA Choice) carcasses. In addition, tenderloin (psoas major) and eye of round (semitendinosus) subprimals were collected from the same US carcasses to serve as anchors for high and low palatability. All subprimals were aged until 29 to 32 d postmortem. All fabrication and enhancement occurred in Lubbock, Texas. Data were analyzed initially as a randomized complete design and subsequently as a split-split plot design, with the main effects of country of origin/diet (Australian grain-fed, Australian grass-fed, and US grain-fed), muscle (LL and GM), and enhancement (0% or 7%) and all potential interactions as fixed effects. Enhancement significantly improved palatability in both LL and GM steaks as evidenced by greater (P < 0.05) consumer ratings for tenderness, juiciness, flavor liking, overall liking, and satisfaction. Enhancing LL steaks resulted in consumer responses that were comparable or superior to consumer responses for psoas major samples. Similarly, enhancing GM steaks resulted in consumer responses that were comparable or superior to nonenhanced LL samples. Consumers reacted least favorably to nonenhanced Australian grass-fed beef as they rated all palatability traits lowest (P < 0.05) for both LL and GM samples. However, enhancing grassfed beef resulted in consumer responses that were similar (P > 0.05) to nonenhanced grain-fed beef. This response to enhancement was observed in consumer scores for both LL and GM samples. Consumers could not detect differences (P > 0.05) in tenderness, juiciness, flavor, overall liking, or satisfaction between grain-fed beef from Australia and the US.
Ragam Spesies dan Karakteristik Habitat Nyamuk di Kecamatan Juai, Kabupaten Balangan, Provinsi Kalimantan Selatan
Authors: Supriyono Supriyono , Tan Suriyani , Hadi Upik Kesumawati
Published: February 2020

Filariasis is a mosquito borne disease which caused by filarial worm. In addition, beside causing ahigh morbidity rate and socioeconomic losses, the disease may also decrease the human productivity. Thecontrol efforts have been done by vector control program, yet still not effective. This is due to a lack ofunderstanding of the biology of mosquito vector. The aim of this research was to determine diversity ofmosquitoes, density, behavior, characteristic habitat and their role of filariasis transmission. The researchwas conducted from Januari to April 2015 in Hamarung and Hukai Villages, Juai Subdistrict, BalanganDistrict, South Kalimantan Province. Collection of mosquitoes was done by bare leg bait indoor collectionmethod and outdoor collection method from 06.00 pm–06.00 am. In additon, larvae were collected in theirpotencial habitats. There were 15 species mosquitoes comprising of 5 genera i.e. genus of Culex, Mansonia,Anopheles, Armigeres, and Aedes. There were 5 dominant species of mosquitoes i.e. Cx. tritaeniorhynchus(36.80%), Cx. quinquefasciatus (29.60%), Ma. dives (11.73%), Ma. annulata (10.04%) dan Ma. uniformis(4.62%). The peak activity of Cx. tritaeniorhynchus and Cx. quinquefasciatus in both villages occurred at21.00–00.45. Based on the habitat of mosquitoes, genus of Culex, Mansonia and Anopheles were found inswamps. Mosquitoes dissection did not show any microfilaria stages (L1, L2, L3).
The Timeliness of XBRL Filings: An Empirical Examination
Authors: Howard Jennifer , Zhou Jie
Published: February 2020

This study examines the timeliness of XBRL data filings. To be timely, the XBRL data must be filed concurrently with the 10-K filing. Using a matched sample of non-timely (NT) and timely XBRL filers over the period 2009–2016, we investigate factors associated with the timeliness of XBRL. We find that NT XBRL filings are more likely when the filing is more complex and when the filer changes auditors. In contrast, using a service provider with more experience and a Big 4 auditor are positively associated with XBRL filing timeliness. NT XBRL filers also experience more negative market-adjusted stock returns compared to the timely XBRL filers. These findings may inform regulators about the implementation of XBRL. Regulators may want to consider these factors in future efforts to use technological advances to improve accessibility to information.

JEL Classifications: M15; M48.
DAYA TAHAN HIDUP SPERMATOZOA EPIDIDIMIS KAMBING KACANG DENGAN MENGGUNAKAN LARUTAN PENGENCER TRIS KUNING TELUR PADA SUHU 5°C
Authors: Satria Haris , Hendri J , Afrianti F
Published: February 2020

Tujuan dari penelitian ini adalah untuk mengamati kualitas spermatozoa epididimis kambing kacang  yang di preservasi pada suhu 5°C. Spermatozoa dikumpulkan dari bagian cauda epididimis dengan kombinasi metode slicing dan penekanan. Parameter yang diamati adalah persentase motilitas progresif sperma hidup dan abnormalitas. Hasil penelitian menunjukkan bahwa persentase motilitas progresif semen cauda epididimis setelah preservasi 0, 1, 2 dan 3 jam adalah  tidak pengaruh nyata (P>0,05). Selanjutnya persentase hidup berpengaruh sangat nyata (P<0,01) dengan nilai rataan perlakkuan tertinggi didapat pada lama simpan ke 0 jam yaitu 66,875±19,49%. Untuk persentase abnormalitas tidak memberikan pengaruh yang nyata (P>0,05). Dapat disimpulkan, bahwa pengaruh lama preservasi semen cauda epididimis yang berbeda pada suhu 5˚C tidak berpengaruh nyata (P>0,05) terhadap persentase motilitas dan persentase abnormalitas, dan berpengaruh sangat nyata (P<0,01) terhadap persentase hidup.
PEMANFAATAN TEPUNG DAUN APU-APU (Pistia stratiotes) DALAM RANSUM BASAL TERHADAP ORGAN PENCERNAAN AYAM RAS PEDAGING
Authors: Erwan Edi
Published: February 2020

Water lettuce meal (Pistia stratiotes) is the weed that has potential as animal feed due to it contain high crude protein and energy metabolism. The aims of this study wasto determine the weight and length of digestive organs including proventriculus, ventriculus, small intestine in broiler chicken given of water lettuce meal (WLM) in ratios. The research design of this study was a completely randomized design (CRD) with five treatments and four replications. The treatments consisted of T0 (commercial feed without WLM), T1 (ration with 0% WLM), T2 (ration with 5% WLM), T3 (ration with 10% WLM) and T4 (ration with 15% WLM). The experimental animal used were broiler DOC until the age of 35 days old were kept in 20 cages and each cage consisted of 3 broiler chickens. The parameters measured were proventriculusweight, ventriculus weight, small intestine weight and length of the small intestine. The results showed that there was no significant effects among treatments on all parameters. The conclusions of the study that the use of indicate that WLM could be used as feed up to 15% in ration without affecting their the proventriculus weight, ventrikulus weight, small intestine weight and length small intestineinbroiler chickens.
LAS TEORÍAS DE LA ADMINISTRACIÓN, EL CONFLICTO Y LA INVESTIGACIÓN PARA LA PAZ
Authors: García Bernardo N. Sánchez , Ortegón René Vargas
Published: February 2020

Las teorías de la administración y la investigación para la paz son de reciente desarrollo, iniciaron su conformación en las primeras décadas del siglo XX, y recíprocamente se han excluido, por lo que este artículo desarrolla un diálogo entre las dos que permite contribuir a una interpretación conjunta del conflicto en la empresa, así como su reconocimiento y análisis académico. Para ello se ha efectuado un recorrido por las distintas teorías y su interpretación del conflicto en la empresa, verificando sus coincidencias y distanciamientos con la investigación para la paz, así como las carencias que muestra una con respecto a la otra.