bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of interactive sport measurement test learning media
Authors: Tantri Afri , Siregar Abdul Hakim , Hasibuan Nurman , Aprial. M Benny
Published: November 2023

Media is one of the factors that support the success of the learning process, but there are still several shortcomings in the use of media to support learning. The aim of this research is to produce learning media in the physical education measurement test subject based on interactive multimedia, with product results in the form of mobile applications, interactive VCDs, printed books, and indexed reputable international journals which will later be used both in learning activities and in independent learning to facilitate in delivering learning material for physical education measurement tests. This study used the research and development approach from Borg and Gall. The target products or users in this study were lecturers in the sport’s physical education measurement test course. The subjects in this study were all PJKR FIK Unimed students who took the sport physical education measurement test course. The findings of the small group test showed that the questionnaire product had a total score of 565, an average of 28.25, and a total percentage of 70.62% in a small trial with a fairly valid category (used). The product could thus be used in this study, but the authors chose to carry out a large group trial to validate the product. Based on the findings of the large group test, the product questionnaire has a total score of 1369, an average of 34.22, and an overall percentage of 85.56% in a small trial with a very valid (used) category. Paired T-test employed to validate the product. Tcount = 5.11 determined from the findings of the calculation of the effectiveness test data. Pricing t-table = 2.08 calculated from the distribution list t using probability 1- = 0.95 and dk n-1 (30-1) = 1. This is mean there is an effect of learning media on interactive multimedia - sport-based measurement test, so that t count t table. It can be concluded that the interactive sports measurement test learning media in this study are well developed, valid, and effective to improve sport measurement test learning outcome.
The effect of barrier hops and bench jumping exercises on increasing Inkado athletes’ speed in mawashi geri
Authors: Marlina Leni , Syamsuar Syamsuar , Damrah Damrah , Ilham Ilham , Septri Septri , Sibomana Alexandre
Published: November 2023

This study aim to determineeffect of barrier hops and bench jumping exercises on increasing Inkado athletes’ speed in mawashi geri. This study employed an experimental method with a two groups pretest-posttest design. The research population was athletes form Inkado Tanjungpinang City. The sampling technique used purposive sampling, with the criteria that (1) attendance was at least 75% (actively participating in training). (2) sampel were athletes who participated in training at Dojo Inkado Tanjungpinang City with an age range of 9-19 years, (3) gender male and female. (4) the length of the training period is at least 6 months. Based on these criteria, there were 24 people. Tthe barrier hops hypothesis test with a significant value of 0.000, jumping up and down the bench is 0.000, and the corparison of the two experiments is 0.119. The results showed that based on the T test found a significant value of 0.119 greater than 0.05. These results explain that there is no significant difference between the Posttest Barrier Hops Exercise and Bench Jump Exercises for Mawashi Geri in Karate. The Posttest average of the Barrier Hops group was 72.83 and the group Jumping Up and Down the Benc had an average of 74.00. seen from the difference in the posttest value of barrier hop and jumoing up and down the banch is 1.167. Thus the duffereence in the posttest shows that jumping up and down the bench is better than barrier hops exercise to improve mawashi geri in karate.
A combination of split jumps and short sprints to increase the volleyball athletes’ leg muscle power and agility
Authors: Yoda I Ketut , Kusuma Ketut Chandra Adinata , Suwiwa I Gede , Silva Hendriketa Da
Published: November 2023

pplying the right training methods can lead to optimal athlete performance. The use of one training method is common, and the use of a combination of two training methods is something new in training. The purpose of this study was to reveal the effectiveness of the combination of split jump training as a plyometric exercise with short sprint training on the leg muscle power capacity and agility of volleyball players. The research method in this research is a quasi experiment involving 40 samples (age: 20.85 ± 0.89 years, height: 178.69 ± 6.51 cm, and weight: 72.47 ± 8.02 kg). This study used a modified randomized pre-test and post-test design without a control group. The population of this study were volleyball players at Universitas Pendidikan Ganesha (Undiksha). Purposive sampling was chosen to determine the sample, namely 40 male student players.The sample was given training combining split jumps with short sprints for 4 weeks with details of 12 training sessions (3 times a week). The Jumpa DF and agility t-test were chosen as instruments to measure leg muscle power and agility. The collected data was analyzed using a paired t-test with a significance level of 5%. Before testing the hypothesis, start by testing the normality of the data using the Kolmogorov-Smirnova test and the homogeneity of the data using Levene’s with the help of SPSS 16.0. The results achieved show that there is a significant influence on the leg muscle power (sig 0.05) and agility (sig 0.05) of volleyball players. Based on the results of this data analysis, it can be concluded that the combination of split jump and short sprint training for 4 weeks has a significant effect on the results of leg muscle power and agility in male volleyball players. Seeing the findings above, it is hoped that volleyball coaches can apply this training method, specifically in the pre-competition phase, which requires a short time to improve leg muscle strength and agility at the same time.
The Effect of Various Levels of Nitrogen, Phosphorus and Potassium on Production Of Local Red Onion
(Allium Cepa L .)
Authors: F. Saeed Dilzar , T.R. Dizayee Alwand
Published: November 2023

Fertilization is one of the efforts done by farmers to increase the production and
quality of onions. The research aimed to find out the effect of different levels of
nitrogen, phosphorus, and potassium fertilizers on the growth and production of
onions. The research was conducted in the Grdarash field, the experimental farm
of the College of Agriculture, University of Salahaddin. The research used a
spilt–spilled design. The first factor was nitrogen (0, 40, 80, 160 Kg .ha1
). The
second factor was phosphorus (0, 80, 160 Kg.ha-1
), and the third was Potassium
(0, 50, 100 Kg .ha-1
). The results indicated a highly significant interaction between NPK and onion bulb yield. The treatment (K1 P2 N1) has the highest significant yield production (18 .36 Mg. ha-1
) And the best interaction between the
nitrogen, phosphorus and potassium fertilizers; this treatment addition was (K 50,
P 160 and N 40 Mg .ha-1
). K1 P1 was the most significant interaction between
Potassium and Phosphorus. K1 N1 was the most significant interaction between
Potassium and Nitrogen.
Keywords: Nitrogen, Phosphorus, Potassium, Onion, Bulb yield
Combination effect of different levels of Nitrogen, Phosphorus and
Potassium on the yield of Chickpea Plant (Cicera rietinum L.)
Authors: Abd Sabri Yahya A.A , Dizayee Alwand T.R.
Published: November 2023

This experiment was conducted at Grdarasha field of the College of Agricultural
Engineering Science, Salahaddin University in Erbil, with a Clay Loam texture
class. During the spring growing season of 2020, to study the effect of four levels
of phosphorus TSP (0, 20, 40, 60) Kg P. ha-1. Three levels of K (0, 15, 30) Kg K.
ha-1 and three levels of N (0, 15, 30) Kg N. ha-1. Besides, there was a combination of yield components and nutrient balance of the chickpea plant using a splitblock design with three factors (K, N and P), where 36 treatment with 3 replicates
was used.
The main results could be summarized as follows: The combination of potassium,
nitrogen, and phosphorus levels affected the yield of the chickpea plant significantly. Also, the maximum yield recorded in the treatment combination
(K2N1P2) was (1.55 Mg ha-1). In comparison, the lowest mean value (0.73 Mg
ha-1) was recorded from the treatment combination (K0N0P0).
Keywords: Nitrogen, Phosphorus, Potassium, chemical and physical properties,
chickpea yield
User-Guided Enhancements to a Technology-Facilitated Resilience Program to Address Opioid Risks Following Traumatic Injury in Youth: Qualitative Interview Study
Authors: Adams Zachary W , Marriott Brigid R , Karra Swathi , Linhart-Musikant Elizabeth , Raymond Jodi L , Fischer Lydia J , Bixler Kristina A , Bell Teresa M , Bryan Eric A , Hulvershorn Leslie A
Published: November 2023

Background

Youth with traumatic injury experience elevated risk for behavioral health disorders, yet posthospital monitoring of patients’ behavioral health is rare. The Telehealth Resilience and Recovery Program (TRRP), a technology-facilitated and stepped access-to-care program initiated in hospitals and designed to be integrated seamlessly into trauma center operations, is a program that can potentially address this treatment gap. However, the TRRP was originally developed to address this gap for mental health recovery but not substance use. Given the high rates of substance and opioid use disorders among youth with traumatic injury, there is a need to monitor substance use and related symptoms alongside other mental health concerns.

Objective

This study aimed to use an iterative, user-guided approach to inform substance use adaptations to TRRP content and procedures.

Methods

We conducted individual semistructured interviews with adolescents (aged 12-17 years) and young adults (aged 18-25 years) who were recently discharged from trauma centers (n=20) and health care providers from two level 1 trauma centers (n=15). Interviews inquired about reactions to and recommendations for expanding TRRP content, features, and functionality; factors related to TRRP implementation and acceptability; and current strategies for monitoring patients’ postinjury physical and emotional recovery and opioid and substance use. Interview responses were transcribed and analyzed using thematic analysis to guide new TRRP substance use content and procedures.

Results

Themes identified in interviews included gaps in care, task automation, user personalization, privacy concerns, and in-person preferences. Based on these results, a multimedia, web-based mobile education app was developed that included 8 discrete interactive education modules and 6 videos on opioid use disorder, and TRRP procedures were adapted to target opioid and other substance use disorder risk. Substance use adaptations included the development of a set of SMS text messaging–delivered questions that monitor both mental health symptoms and substance use and related symptoms (eg, pain and sleep) and the identification of validated mental health and substance use screening tools to monitor patients’ behavioral health in the months after discharge.

Conclusions

Patients and health care providers found the TRRP and its expansion to address substance use acceptable. This iterative, user-guided approach yielded novel content and procedures that will be evaluated in a future trial.
The Alzheimer’s Knowledge Base: A Knowledge Graph for Alzheimer Disease Research
Authors: Romano Joseph D , Truong Van , Kumar Rachit , Venkatesan Mythreye , Graham Britney E , Hao Yun , Matsumoto Nick , Li Xi , Wang Zhiping , Ritchie Marylyn D , Shen Li , Moore Jason H
Published: November 2023

Background

As global populations age and become susceptible to neurodegenerative illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data resources for drug discovery and repurposing fail to capture relationships central to the disease’s etiology and response to drugs.

Objective

We designed the Alzheimer’s Knowledge Base (AlzKB) to alleviate this need by providing a comprehensive knowledge representation of AD etiology and candidate therapeutics.

Methods

We designed the AlzKB as a large, heterogeneous graph knowledge base assembled using 22 diverse external data sources describing biological and pharmaceutical entities at different levels of organization (eg, chemicals, genes, anatomy, and diseases). AlzKB uses a Web Ontology Language 2 ontology to enforce semantic consistency and allow for ontological inference. We provide a public version of AlzKB and allow users to run and modify local versions of the knowledge base.

Results

AlzKB is freely available on the web and currently contains 118,902 entities with 1,309,527 relationships between those entities. To demonstrate its value, we used graph data science and machine learning to (1) propose new therapeutic targets based on similarities of AD to Parkinson disease and (2) repurpose existing drugs that may treat AD. For each use case, AlzKB recovers known therapeutic associations while proposing biologically plausible new ones.

Conclusions

AlzKB is a new, publicly available knowledge resource that enables researchers to discover complex translational associations for AD drug discovery. Through 2 use cases, we show that it is a valuable tool for proposing novel therapeutic hypotheses based on public biomedical knowledge.
Predictors of Use and Drop Out From a Web-Based Cognitive Behavioral Therapy Program and Health Community for Depression and Anxiety in Primary Care Patients: Secondary Analysis of a Randomized Controlled Trial
Authors: Rotondi Armando J , Belnap Bea Herbeck , Rothenberger Scott , Feldman Robert , Hanusa Barbara , Rollman Bruce L
Published: November 2023

Background

A previously reported study examined the treatment of primary care patients with at least moderate severity depressive or anxiety symptoms via an evidence-based computerized cognitive behavioral therapy (CCBT) program (Beating the Blues) and an online health community (OHC) that included a moderated internet support group. The 2 treatment arms proved to be equally successful at 6-month follow-up.

Objective

Although highly promising, e-mental health treatment programs have encountered high rates of noninitiation, poor adherence, and discontinuation. Identifying ways to counter these tendencies is critical for their success. To further explore these issues, this study identified the primary care patient characteristics that increased the chances patients would not initiate the use of an intervention, (ie, not try it even once), initiate use, and go on to discontinue or continue to use an intervention.

Methods

The study had 3 arms: one received access to CCBT (n=301); another received CCBT plus OHC (n=302), which included a moderated internet support group; and the third received usual care (n=101). Participants in the 2 active intervention arms of the study were grouped together for analyses of CCBT use (n=603) because both arms had access to CCBT, and there were no differences in outcomes between the 2 arms. Analyses of OHC use were based on 302 participants who were randomized to that arm.

Results

Several baseline patient characteristics were associated with failure to initiate the use of CCBT, including having worse physical health (measured by the Short Form Health Survey Physical Components Score, P=.01), more interference from pain (by the Patient-Reported Outcomes Measurement Information System Pain Interference score, P=.048), less formal education (P=.02), and being African American or another US minority group (P=.006). Characteristics associated with failure to initiate use of the OHC were better mental health (by the Short Form Health Survey Mental Components Score, P=.04), lower use of the internet (P=.005), and less formal education (P=.001). Those who initiated the use of the CCBT program but went on to complete less of the program had less formal education (P=.01) and lower severity of anxiety symptoms (P=.03).

Conclusions

This study found that several patient characteristics predicted whether a patient was likely to not initiate use or discontinue the use of CCBT or OHC. These findings have clear implications for actionable areas that can be targeted during initial and ongoing engagement activities designed to increase patient buy-in, as well as increase subsequent use and the resulting success of eHealth programs.

Trial Registration

ClinicalTrials.gov NCT01482806; https://clinicaltrials.gov/study/NCT01482806
Developing and Evaluating Digital Public Health Interventions Using the Digital Public Health Framework DigiPHrame: A Framework Development Study (Preprint)
Authors: Jahnel Tina , Pan Chen-Chia , Pedros Barnils Núria , Muellmann Saskia , Freye Merle , Dassow Hans-Henrik , Lange Oliver , Reinschluessel Anke V , Rogowski Wolf , Gerhardus Ansgar
Published: November 2023

BACKGROUND

Digital public health (DiPH) interventions may help us tackle substantial public health challenges and reach historically underserved populations, in addition to presenting valuable opportunities to improve and complement existing services. However, DiPH interventions are often triggered through technological advancements and opportunities rather than public health needs. To develop and evaluate interventions designed to serve public health needs, a comprehensive framework is needed that systematically covers all aspects with relevance for public health. This includes considering the complexity of the technology, the context in which the technology is supposed to operate, its implementation, and its effects on public health, including ethical, legal, and social aspects.

OBJECTIVE

We aimed to develop such a DiPH framework with a comprehensive list of core principles to be considered throughout the development and evaluation process of any DiPH intervention.

METHODS

The resulting digital public health framework (DigiPHrame) was based on a scoping review of existing digital health and public health frameworks. After extracting all assessment criteria from these frameworks, we clustered the criteria. During a series of multidisciplinary meetings with experts from the Leibniz ScienceCampus Digital Public Health, we restructured each domain to represent the complexity of DiPH. In this paper, we used a COVID-19 contact–tracing app as a use case to illustrate how DigiPHrame may be applied to assess DiPH interventions.

RESULTS

The current version of DigiPHrame consists of 182 questions nested under 12 domains. Domain 1 describes the current status of health needs and existing interventions; domains 2 and 3, the DiPH technology under assessment and aspects related to human-computer interaction, respectively; domains 4 and 5, structural and process aspects, respectively; and domains 6-12, contextual conditions and the outcomes of the DiPH intervention from broad perspectives. In the CWA use case, a number of questions relevant during its development but also important for assessors once the CWA was available were highlighted.

CONCLUSIONS

DigiPHrame is a comprehensive framework for the development and assessment of digital technologies designed for public health purposes. It is a living framework and will, therefore, be updated regularly and as new public health needs and technological advancements emerge.
Pooled Cohort Profile: ReCoDID Consortium’s Harmonized Acute Febrile Illness Arbovirus Meta-Cohort (Preprint)
Authors: Gómez Gustavo , Hufstedler Heather , Montenegro Morales Carlos , Roell Yannik , Lozano-Parra Anyela , Tami Adriana , Magalhaes Tereza , Marques Ernesto T A , Balmaseda Angel , Calvet Guilherme , Harris Eva , Brasil Patricia , Herrera Victor , Villar Luis , Maxwell Lauren , Jaenisch Thomas ,   ReCoDID Arbovirus harmonization study group
Published: November 2023

UNSTRUCTURED

Infectious disease (ID) cohorts are key to advancing public health surveillance, public policies, and pandemic responses. Unfortunately, ID cohorts often lack funding to store and share clinical-epidemiological (CE) data and high-dimensional laboratory (HDL) data long term, which is evident when the link between these data elements is not kept up to date. This becomes particularly apparent when smaller cohorts fail to successfully address the initial scientific objectives due to limited case numbers, which also limits the potential to pool these studies to monitor long-term cross-disease interactions within and across populations. CE data from 9 arbovirus (arthropod-borne viruses) cohorts in Latin America were retrospectively harmonized using the Maelstrom Research methodology and standardized to Clinical Data Interchange Standards Consortium (CDISC). We created a harmonized and standardized meta-cohort that contains CE and HDL data from 9 arbovirus studies from Latin America. To facilitate advancements in cross-population inference and reuse of cohort data, the Reconciliation of Cohort Data for Infectious Diseases (ReCoDID) Consortium harmonized and standardized CE and HDL from 9 arbovirus cohorts into 1 meta-cohort. Interested parties will be able to access data dictionaries that include information on variables across the data sets via Bio Studies. After consultation with each cohort, linked harmonized and curated human cohort data (CE and HDL) will be made accessible through the European Genome-phenome Archive platform to data users after their requests are evaluated by the ReCoDID Data Access Committee. This meta-cohort can facilitate various joint research projects (eg, on immunological interactions between sequential flavivirus infections and for the evaluation of potential biomarkers for severe arboviral disease).
Capitalizing on Community Groups to Improve Women’s Resilience to Maternal and Child Health Challenges: Protocol for a Human-Centered Design Study in Tanzania (Preprint)
Authors: Isangula Kahabi Ganka , Usiri Aminieli Itaeli , Pallangyo Eunice Siaity
Published: November 2023

BACKGROUND

Maternal and neonatal deaths remain a major public health issue worldwide. Income Generation Associations (IGAs) could form a critical entry point to addressing poverty-related contributors. However, there have been limited practical interventions to leverage the power of IGAs in addressing the challenges associated with maternal care and childcare.

OBJECTIVE

This study aims to co-design an intervention package with women in IGAs to improve their readiness and resilience to address maternal and child health (MCH) challenges using a human-centered design approach.

METHODS

The study will use a qualitative descriptive design with purposefully selected women in IGAs and key MCH stakeholders in the Shinyanga and Arusha Regions of Tanzania. A 4-step adaptation of the human-centered design process will be used involving (1) mapping of IGAs and exploring their activities, level of women’s engagement, and MCH challenges faced; (2) co-designing of the intervention package to address identified MCH challenges or needs considering the perceived acceptability, feasibility, and sustainability; (3) validation of the emerging intervention package through gathering insights of women in IGAs who did not take part in initial steps; and (4) refinement of the intervention package with MCH stakeholders based on the validation findings.

RESULTS

The participants, procedures, and findings of each co-design step will be presented. More specifically, MCH challenges facing women in IGAs, a list of potential solutions proposed, and the emerging prototype will be presented. As of August 2024, we have completed the co-design of the intervention package and are preparing validation. The findings from the validation of the emerging prototype with a new group of women in IGAs and its refinement through multistakeholder engagement will be presented. A final co-designed intervention package with the potential to improve women’s resilience and readiness to handle MCH challenges will be generated.

CONCLUSIONS

The emerging intervention package will be discussed given relevant literature on the topic. We believe that subsequent testing and refinement of the package could form the basis for scaling up to broader settings and that the package could then be promoted as one of the key strategies in addressing MCH challenges facing women in low- and middle-income countries.

CLINICALTRIAL

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/54323
Responding to the Return of Influenza in the United States by Applying Centers for Disease Control and Prevention Surveillance, Analysis, and Modeling to Inform Understanding of Seasonal Influenza (Preprint)
Authors: Borchering Rebecca K , Biggerstaff Matthew , Brammer Lynnette , Budd Alicia , Garg Shikha , Fry Alicia M , Iuliano A Danielle , Reed Carrie
Published: November 2023

UNSTRUCTURED

We reviewed the tools that have been developed to characterize and communicate seasonal influenza activity in the United States. Here we focus on systematic surveillance and applied analytics, including seasonal burden and disease severity estimation, short-term forecasting, and longer-term modeling efforts. For each set of activities, we describe the challenges and opportunities that have arisen because of the COVID-19 pandemic. In conclusion, we highlight how collaboration and communication have been and will continue to be key components of reliable and actionable influenza monitoring, forecasting, and modeling activities.
Luce Irigaray and Women in Sylvia Plath’s Paralytic
Authors: Karo Hasan Hussein
Published: November 2023

This study discusses the condition of the women during 1950s and 1960s. She generalizes her state as being a woman living among a male-dominated society. Her mental state and dissatisfaction reflect her life as a female poet. This study justifies her hatred of men through some notions of the French feminist Luce Irigaray to analyze Plath’s feelings and emotions regarding her hatred towards men. The motives behind her suicidal attempts are explained in this study as well as the fears that she holds in her heart about present and future.
Exploring the Nexus of Memory, Power, and Identity in Lois Lowry’s The Giver and Yoko Ogawa’s The Memory Police
Authors: Jaithalia Nandini
Published: November 2023

The study of memory, power, and identity explores how power dynamics within societies shape the construction and preservation of collective and individual memories, ultimately influencing the formation and evolution of identities. Accordingly, this research delves into the intricate relationship between memory, identity, and power by analysing two dystopian novels, Lois Lowry’s The Giver and Yoko Ogawa’s The Memory Police. In both the narratives, the theme of memory and its profound influence is apparent. Lowry drew inspiration from her father’s memory loss, prompting her exploration of a world where painful memories are intentionally eliminated. Ogawa pays homage to Anne Frank’s The Diary of a Young Girl and explores contemporary anxieties surrounding surveillance, media manipulation, and authoritarianism. This study seeks to examine how the manipulation of memory by authoritarian regimes impacts the sense of self and collective identity in both the texts. Drawing from the methods of memory studies and literary analysis, the paper explores how the characters in these novels navigate a world where memories are controlled, suppressed, or erased, leading to a disruption in the formation of individual and group identities. Through a comparative analysis of the two works, the paper uncovers the ways in which the manipulation of memory serves as a tool for maintaining dominance and shaping collective consciousness, ultimately distorting individual and communal identities. This study ultimately reveals how language and writing can also be used to resist the dominance of authoritarian regimes over the perceptions of the past, present, and future of individuals and communities.
A Review on Antihyperlipidemic Activity of Medicinal Plants
Authors: Shedage Ashish Tukaram , Pinjari Rukhsana Mahiboob
Published: November 2023

The researchers wanted to see whether any plants had any antihyperlipidemic action, therefore they conducted this investigation. It's the single greatest contributor to potential cardiovascular problems. As a result, there are several negative effects associated with allopathic antihyperlipidemic medications. Many people rely on medicinal plants as a means of treatment, and this has a substantial effect on the world economy. In many parts of the world's healthcare infrastructure, herbal treatments made from herbs, herbs, and herbs play a crucial role. Herbal medication is becoming more popular as people seek for safer, more easily accessible alternatives. The purpose of this study was to assess the antihyperlipidemic efficacy of herbal plants. Important medicinal herbs have been shown to have hyperlipidemic action.
(Epi)genealogía del cuerpo generizado
Authors: Ciccia Lu
Published: November 2023

En este texto abordo una de las propuestas ontológicas, epistémicas y metodológicas que sintetiza mejor el trabajo de las epistemologías feministas sobre cómo conceptualizar las nociones de género y sexo, así como su relación en el ámbito biológico. Describo los alcances y limitaciones de esta propuesta y muestro que la propia noción de sexo implica un sesgo androcéntrico desde el que se legitima la dicotomía endógeno/exógeno, un reduccionismo funcional, la idea de coherencia interna y la reducción de nuestra complejidad biológica a los rasgos vinculados con la reproducción respecto a las diferencias biológicas en general y, como mostraré, en el ámbito biomédico en particular al caracterizar las prevalencias y el desarrollo de enfermedades. En contraste, propongo la idea de epigenealogía para una reconceptualización histórica de nuestra materialidad biológica capaz de profundizar en cómo nuestra plasticidad a través de los procesos epigenéticos danza sincrónicamente con nuestra experiencia social, contingente y situada.
Programming 2DoF Robot Arm Based on Forward Kinematics using Arduino
Authors: Srilatha T.
Published: November 2023

This project's main goal is to use Arduino to program a 2-degree-of-freedom (2Dof) robot arm based on forward kinematics. The suggested system is made to precisely regulate the robot arm's motion for a variety of activities, such as pickand-place duties and assembly procedures. The robot arm can be precisely positioned and controlled thanks to the forward kinematics model, which determines the end effector's position based on the joint angles. The system is put into practice and put through its paces in a real-world setting, and the results demonstrate its ability to conduct precise movements with decent accuracy. The 2DoF Robot Arm can be utilized to automate complex processes and boost productivity in a variety of industries, including manufacturing, healthcare, and robotics research.
PENGARUH SOCIAL MEDIA MARKETING TERHADAP BRAND AWARENESS DAN PURCHASE INTENTION KONSUMEN BRAND SKINCARE AVOSKIN DI KOTA BANDUNG
Authors: Pahlevi Aqshel Reza , Trianasari Nurvita
Published: November 2023

Abstract: The post-modern business era has provided many opportunities such as social media and offers many challenges to business sustainability. Covering almost all age groups and different regions, the use of social media makes this digital platform a way to showcase a brand. To build its brand, Avoskin uses various digital platforms, such as social networks, websites and e-commerce. Social media marketing can influence consumer interests, interests, decisions, in choosing products or services, consumers choose products that are familiar or suitable. This research examines the influence of social media marketing on brand awareness and purchase intention of consumers of the Avoskin skincare brand in Bandung. The object of this research is consumers of the Avoskin skincare brand in Bandung. The method used in this research is quantitative with a Structural Equation Modeling (SEM) approach with a PLS approach with the help of data processing software SmrtPLS 4.0. Data collection uses an online questionnaire.Keywords: Social Media Marketing; Brand Awareness; Purchase Intention.Abstrak: Era bisnis pasca modern telah memberikan banyak peluang seperti adanya sosial media dan menawarkan banyak tantangan pada keberlanjutan bisnis. Mencakup hampir semua kelompok umur dan wilayah yang berbeda, penggunaan media sosial menjadikan platform digital ini sebagai cara untuk memamerkan sebuah brand. Untuk membangun mereknya, Avoskin menggunakan berbagai platform digital, seperti jejaring sosial, website, dan e-commerce. Social media marketing dapat mempengaruhi minat, ketertarikan, keputusan konsumen, dalam memilih produk atau jasa, konsumen memilih produk yang familiar atau cocok. Penelitian ini menguji pengaruh social media marketing terhadap brand awareness dan purchase intention konsumen brand skincare Avoskin di Bandung. Objek penelitian ini adalah konsumen brand skincare Avoskin di Bandung. Metode yang digunakan dalam penelitian ini adalah kuantitatif dengan pendekatan Structural Equation Modeling (SEM) dengan pendekatan PLS dengan bantuan pengolahan data software SmrtPLS 4.0. Pengambilan data menggunakan kuesioner online.Kata Kunci: Social Media Marketing; Brand Awareness; Purchase Intention.
General Considerations in Managing Non-Odontogenic Orofacial Pain
Authors: R. Sonar Dr. Prasanna , S. Panchbhai Dr. Aarati
Published: November 2023

Orofacial pain is characterized as facial and mouth discomfort. The most prevalent inflammatory pain to appear in this area is dental pain. However, chronic pain illnesses, such as temporomandibular joint disorders, primary headaches (neurovascular), neuropathic pain, and idiopathic pain, can commonly mimic toothaches. Dentistry's specialty in orofacial pain focuses on diagnosing and treating persistent, complicated facial pain and oromotor disorders. This area of dentistry has grown throughout time due to the desire to comprehend better a group of patients who, for some reason, were not experiencing tooth pain issues. Orofacial discomfort has a major impact on morbidity and the use of medical services. Several illnesses can cause orofacial discomfort; diagnostic uncertainty is commonly seen in clinical practice. Due to their varying pain presentation, toothaches can resemble many chronic episodic orofacial pain syndromes, leading to many improperly prescribed antibiotic regimens and surgical treatments. Ear, nose, throat, and maxillofacial surgeons also fall victim to the misdiagnosis, making them not the only professionals to suffer from it. The orofacial region's complex diversity makes it difficult for doctors to handle non-odontogenic pain with an oral origin. The physician must be well-versed in the many pain problems affecting the orofacial area and the various alternatives accessible for their best care to provide a precise diagnosis and successful treatment. This paper focuses on the different types of pain, characteristics, assessments, investigations, and general considerations in managing non-odontogenic pain of the orofacial region. To adequately manage these patients, our profession has come to understand how important a fundamental understanding of orofacial pain is. Many improvements have been brought about by this adjustment in the approach in both clinical and educational settings. This review covers all general aspects of orofacial pain management.
POTENSI SUMBERDAYA AIR SEBAGAI PEMBANGKIT LISTRIK TENAGA MIKROHIDRO (PLTMH) DALAM MENCAPAI SUSTAINABLE DEVELOPMENT GOALS (SDGS) DI DESA RANTAU KERMAS, KECAMATAN JANGKAT, KABUPATEN MERANGIN, PROVINSI JAMBI
Authors: Deliana Siregar Anggi , Juventa Juventa , Ritonga D.M. Magdalena , Larasati Niken , Annura Rizky Shazkya
Published: November 2023

Energy resources are resources that can be processed by humans so that they can be used to meet energy needs. Water resources are a renewable natural resource that has a volume with constant conditions in the hydrological cycle. Microhydro Power Plant (PLTMH) is renewable energy that utilizes water resources as an energy producer where the energy produced is classified as small scale energy (less than 200 kW). Electrical energy is energy that is produced from changing other energy that has strength and capacity. Sustainable Development Goals (SDGs) are a new development agreement agreed upon at the UN general assembly in September 2015 with 17 goals to encourage changes towards sustainable development, one of which is regarding clean and affordable energy which is contained in point 7. The location of this research is to determine the potential and estimate the availability of energy to fulfill electricity needs in Rantau Kermas Village,ANGKAt District, Merangin Regency, Jambi Province.
PALEOVOLCANIC KARING RECONSTRUCTION IN THE MERANGIN JAMBI UNESCO GLOBAL GEOPARK TERRITORY BASED ON PETROLOGICAL AND GEOCHEMICAL APPROACH
Authors: Utama Hari wiki , Sutarto Sutarto , Widagdo Asmoro , Wahyudi Eko
Published: November 2023

The presence of lava and pyroclastic sequences in the Karing River on the Merangin Jambi UNESCO Global Geopark territory provides information about the existence of ancient volcanoes. The absence of confirmed rock formations from the distribution of volcanic rock products that have been mapped nationally and also the shape of this ancient volcanic body, is an important reason for this research to be carried out using a petrological approach using petrography and XRF gochemical methods. Petrographic analysis is an appropriate method to determine the mineralogy consist, textures and particular textures, rock structures that are confirmed from field data. Meanwhile, a geochemical approach is used to determine rock oxide compounds. This method aims to reconstruct the shape and type of volcanoes. Research data shows that there are four lava sequences, with Sequence 1 having an entablature structure, Sequence 2 and Sequence 3 having a flow structure, and Sequence 4 having a vesicular-flow structure. The petrography results show that Sequence 1 and Sequence 2 are composed of phenocrysts and microliths of plagioclase, olivine, clinopyroxene, orthopyroxene. Meanwhile, in Sequence 3, hornblende is present, and in Sequence 4, the mineral olivine is absent. The results of geochemical analysis from the four lava sequences are in basalt rocks with 40%-50% Silica content, Calk-alkali basalt magma series, petrogenesis interpreted from the convergence of oceanic subduction beneath continent. The pyroclastic rocks found at the bottom of the lava sequence are evidence of the stratigraphic structure that makes up a volcano originating from the Karing Paleovolcanic, while the pyroclastic rocks found at the top of the lava sequence are believed to originate from other ancient volcanic eruptions. With the stratigraphy composed of lava and pyroclastic sequences, it can be concluded that this ancient volcano is a strato volcano type which is relatively sloping and almost resembles a shield volcano.
Team Building Training To Improve Interpersonal Communication Among Operators At PT Komatsu Indonesia
Authors: Hapsari Maharani Tyas Budi
Published: November 2023

Interpersonal communication is a core skill required by employees in every company. Effective interpersonal communication can be established with strong cooperation between employees. This research aimed to determine the effect of team building training in improving interpersonal communication among operators at PT Komatsu Indonesia. The mixed-method study combined qualitative (interviews and observations) and quantitative (quasi-experiment with one-group pretest-posttest design) approaches. Thirty-six operators were involved in the team building training. The team building training is effective in improving interpersonal skills in operators at PT Komatsu Indonesia (Z=-5.178, p<0.05). The results of this study can be the basis for companies or industries to improve employee interpersonal skills through training to minimize the occurrence of work accidents.
Elastic Nanoparticle-Reinforced, Conductive Structural Color Hydrogel with Super Stretchable, Self-Adhesion, Self-Healing as Electrical/Optical Dual-responsive Visual Electronic Skins
Authors: Xu Min , Liao Junlong , Li Jiajia , Shi Yu , Zhang Ziyu , Fu Yifu , Gu Zhongze , Xu Hua
Published: November 2023

Developing smart hydrogel with excellent physicochemical properties and
multiple signal output capability for interactively electronic skin
still remains challenging. Here, a conductive structural color hydrogels
with desirable physicochemical properties (including high stretchability
and robustness, self-adhesion and self-healing) was developed to provide
synchronous electronic and visual color signals for e-skins. Highly
charged elastic nanoparticles were elaborately used as building units
for structural color and the hydrogel were prepared by the self-assembly
of the nanoparticle to form a non-close-packed array in a mixture
comprised of acrylamide, SF, rGO and then photopolymerization.
Benefiting from the improved interfacial compatibility between flexible
hydrogel network and elastic nanoparticle, covalent cross-linking
network structure and synergistic multiple non-covalent bonding
interactions, the hydrogel exhibits extraordinary mechanical properties,
excellent self-adhesion to diverse substrate and self-healing at room
temperature. In addition, the hydrogel also exhibited sensitive
resistance changes and synchronous structural color changes under
strain. As a proof-to-concept, the hydrogel displayed superior
capability for real-time color-sensing and electrical signal monitoring
of various human motions, the spatial distribution of external
mechanical stimuli as well as identification of different external
stimuli, indicating promising applications in the fields of
interactively visual electronic skin, wearable devices, and
human-machine interfaces.
Chloroplast envelope K + /H + antiporters are involved in cytosol pH regulation.
Authors: Venema Kees , Rodríguez-Rosales María Pilar , Rubio Lourdes , JT Pedersen , Aranda-Sicilia María , JA Fernández
Published: November 2023

KEA1 and KEA2 are K /H
antiporters in the chloroplast inner envelope that adjust stromal pH in
light to dark transitions. We previously determined that stromal pH is
higher in the kea1kea2 mutant cells. Given that cytosol and
chloroplast volume are about equal in mesophyll cells, we wanted to test
if this in turn could cause ionic imbalances in the cytosol as well. In
this study we indeed find that the cytosol is more acidic in the
kea1kea2 mutant. As cytosol pH is tightly controlled by the
activity of the plasma membrane proton ATPase, we tested the activity of
this enzyme. Acidic pH is expected to phosphorylate and activate the
proton ATPase to restore pH. We could however not detect differences in
plasma membrane H -ATPase hydrolytic activity between
Col-0 and the kea1kea2 mutant. No differences in the amount of
plasma membrane H -ATPase enzyme, regulatory 14-3-3
proteins and phosphorylation of H -ATPase Thr932
between Col-0 and the kea1kea2 mutant were detected, indicating
that cytosol acidification did not induce transcriptional regulation or
post-translational phosphorylation of plasma membrane H
-ATPase in the kea1kea2 mutant. Curiously
however, plasma membrane in the double mutant was depolarized,
indicating a reduced electrogenic transport of protons by the ATPase, or
an increased conductance to other ions. We determined that reconstituted
membrane vesicles isolated from kea1kea2 mutants have slightly
lower ATP dependent proton transport activity and appear especially more
permeant to potassium, but also show increased proton conductance.
The therapeutic potential of Neural stem cell-derived exosomes in reducing cerebral ischemic injury: Insights into TLR4/NF-κB pathway regulation.
Authors: Zhao Xue , Liu Ruojing , Zhu Yizhen , Zhu Junde , Chen Shan
Published: November 2023

To explore the mechanism of TLR4/NF-κB regulation of microglia-mediated
inflammation after NSC-Exos transplantation. In this study, a right
middle cerebral artery occlusion model (MCAO) was constructed in SD
rats, NSC-Exos was injected into the lateral ventricle through brain
stereo localization. TAK-242 was given 1 day before MCAO in rats.
Histopathological changes, microglia-mediated inflammatory factor,
colocalized number of CD86/Iba1 and CD206/Iba1 cells, and TLR4/NF-κB
were detected in rats. After brain injury, the number of CD86/Iba1 cells
increased, and the expression of pro-inflammatory factors, TLR4 and
NF-κB were increased. When treatment with NSC-Exos, the number of
CD206/Iba1 cells were increased, and the expression of anti-inflammatory
factors, TLR4 and NF-κB were decreased, promoting anti-inflammatory
phenotype polarization. More importantly, TAK-242 reversed the effect of
NSC-Exos transplantation in animal model. These results suggest that
NSC-Exos can improve the microglia-mediated inflammatory response in
rats with ischemic brain injury, which may be related to the regulation
of TLR4/NF-κB pathway.
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice
Authors: Furber Ellen C. , Hyatt Karissa , Collins Kyla , Yu Xinxin , Droz Brian A. , Holland Adrienne , Friedrich Jessica L. , Wojnicki Samantha , Konkol Debra L. , O’Farrell Libbey S. , Baker Hana E. , Coskun Tamer , Scherer Philipp E. , Kusminski Christine M. , Christe Michael E. , Sloop Kyle W. , Samms Ricardo J.
Published: November 2023

Recent studies have found that glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism can enhance the metabolic efficacy of glucagon-like peptide–1 receptor agonist treatment by promoting both weight-dependent and -independent improvements on systemic insulin sensitivity. These findings have prompted new investigations aimed at better understanding the broad metabolic benefit of GIPR activation. Herein, we determined whether GIPR agonism favorably influenced the pharmacologic efficacy of the insulin-sensitizing thiazolidinedione (TZD) rosiglitazone in obese insulin-resistant (IR) mice. Genetic and pharmacological approaches were used to examine the role of GIPR signaling on rosiglitazone-induced weight gain, hyperphagia, and glycemic control. RNA sequencing was conducted to uncover potential mechanisms by which GIPR activation influences energy balance and insulin sensitivity. In line with previous findings, treatment with rosiglitazone induced the mRNA expression of the GIPR in white and brown fat. However, obese GIPR-null mice dosed with rosiglitazone had equivalent weight gain to that of wild-type (WT) animals. Strikingly, chronic treatment of obese IR WT animals with a long-acting GIPR agonist prevented rosiglitazone-induced weight-gain and hyperphagia, and it enhanced the insulin-sensitivity effect of this TZD. The systemic insulin sensitization was accompanied by increased glucose disposal in brown adipose tissue, which was underlined by the recruitment of metabolic and thermogenic genes. These findings suggest that GIPR agonism can counter the negative consequences of rosiglitazone treatment on body weight and adiposity, while improving its insulin-sensitizing efficacy at the same time.

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