bluuebunny/crossref_metadata_2025 huggingface dataset:
Perspectives on Women's Entrepreneurial Learning and the Evolution of Female Entrepreneurship Research
Authors: Tomos Florica , Clifton Nick , Thurairaj Saraswathy , Balan Oana Cristina
Published: December 2018

The aim of the chapter is to increase the knowledge regarding the methods and styles of learning used by women entrepreneurs in general, and in South East Wales and Malaysia in particular. The research question is What methods and styles of learning do women entrepreneurs employ in their businesses, in general, and specifically in SE Wales and Malaysia? The chapter is a theoretical study with a small empirical extension with two samples of women and men entrepreneurs in the South East Wales. The findings of this chapter support the constructive perspective on learning, adult and social learning, demonstrating the role of social interaction for women entrepreneurs' learning and experiential learning. Through a gender perspective with accent on andragogy, and by designing a model of women entrepreneurial learning, the study shapes a new direction within the research field of women entrepreneurship and constitutes an original contribution to knowledge.
Orthopedic Trauma and Post-Traumatic Stress Disorder
Authors: Starcevic Branislav
Published: December 2018

Little is known about the clinical consequences of psychological morbidity associated with orthopedic trauma. Anxiety disorders, depression, bipolar disorder, schizophrenia, and personality disorders may all occur during the postoperative period. There are no currently clearly defined relations between orthopedic injuries and PTSD, but undoubtedly, we can say that, depending on the personality traits, one can develop PTSD if the orthopedics trauma triggers and induce PTSD in individuals, and that should be one of the main future perspectives and goals of investigative studies. The effectiveness of prevention strategies that could be developed through psychiatrists and orthopedic surgeon cooperation strategies as well as developing strategies when PTSD occur postoperatively should also be one of the main targets in the near future, as PTSD as an entity presents one of the greatest disability factors in society producibility nowadays, which is also very important from the economy perspective.
Changing the Quality of Life After Therapy of Orthodontic Irregularities
Authors: Stojanovic Mirka
Published: December 2018

The effect of orthodontic therapy of different orthodontic anomalies on life quality referred to one's personality. Congenital or acquired orthodontic anomalies are a great problem of today's children and youth. Fast way of life, young mothers urging to be in top form after giving birth to a child, neglecting breastfeeding as a presumption to be the most important for the proper development of the orofacial system leads to numerous irregularities in the teeth development. Maternal deprivation and closeness deprivation, warmth deprivation, present the majority of proper children's development and their psycho-physical development. Any anomaly is evident on the face, either asymmetry, open bite with interlacing the tongue between the teeth, whether in the disorder of the face, the lowered jaw, the incongruous profile and speech disorder, breathing, etc. From the previous, the negative feelings of children and youth, depression, fall in the elimination of life, limitation of working abilities, etc. Solving them leads to joy, happiness, raising the quality of life.
Security, Reliability, and Performance Assessment for Healthcare Biometrics
Authors: Kashyap Ramgopal
Published: December 2018

A health system comprises, all things considered, individuals and activities whose essential purpose is to advance, reestablish, or look after wellbeing. This incorporates endeavors to impact the determinants of wellbeing-enhancing exercises. Biometrics has reformed the human services industry; gadgets can take exceptional data about you from your eye, your imprint, or your thumbprint and utilize it to recognize you. This data is utilized to guarantee that you are who you say you are, and you have the authorization to work with the medicinal services data you are endeavoring to get to. It offers a thorough review of biometric innovation applications intending to electronic social insurance security issues. Information classification, information legitimacy, information respectability, and client/substance verification are discussed in this chapter along with security, which is viewed as a foundation for medicinal services data frameworks as they contain amazingly touchy data.
Indexing for Healthcare Biometric Databases
Authors: Tiwari Kamlesh , Arora Geetika , Gupta Phalguni
Published: December 2018

The healthcare industry offers highly personalized services to its patients. It is necessary to correctly identify the patient and efficiently link his medical records as and when needed. It is important to note that the need of identification arises in many desperate scenarios when the patient may not be able to tell anything about himself. Biometrics can help in this scenario by using physiological or behavioral characteristics. Some of the biometrics traits could be acquired without direct participation of the person, and therefore, the patient need not provide any pin, password, or token for his identification. Biometrics can handle challenges of duplicate medical records and identity theft. However, there is an important issue that may arise when a large number of patients get registered to the system. Increase in the size of the biometric database gradually escalates the time required for identification. This calls for the need of an efficient indexing approach that can confine the search space and decrease the response time. This chapter highlights biometric indexing approaches suitable for the healthcare industry.
Mobile Health (M-Health) for Tele-Wound Monitoring
Authors: Chakraborty Chinmay
Published: December 2018

This chapter describes the implementation of tele-wound monitoring (TWM) for a patient's chronic wound using a smartphone. The system proved to be quick and reliable for providing healthcare at the doorstep. The smartphone-enabled a tele-wound monitoring (TWM) framework, which is used for remote wound monitoring, has been highlighted. The TWM is effective for both rural as well as urban people; it provides good performance in terms of wound monitoring and diagnosis. The objective of this chapter is to design and develop a TWM system model that can acquire, process and monitor chronic wound-related problems by using a low-cost smartphone to increase the overall performance of the system. Specifically, the TWM system is developed for biomedical information like chronic wound processing to monitor important patient information inexpensively and accurately. The implementation is carried out using hypertext preprocessor (PHP) and MySql database and especially by Firebase cloud database, which is used for improving the efficiency.
Mobile Health Applications in Prehospital Emergency Medicine
Authors: Metelmann Bibiana , Metelmann Camilla
Published: December 2018

Prehospital emergency medicine treats time-critical diseases at the emergency site to reduce preventable disabilities and deaths. mHealth can assist in prehospital emergency medicine in multiple ways. This chapter provides insights into emergency medicine and presents three different forms of mHealth in this field. One is a retrieval of medical data (e.g., with aid of smartphone applications). A second one uses unmanned aerial vehicles. And the third one establishes real time communication with medical experts. Examples are given to illustrate the variety of mHealth in prehospital emergency medicine.
The Nexus of M-Health and Self-Care
Authors: Moumtzoglou Anastasius S.
Published: December 2018

Self-care emerged from the concept of health promotion in the 1970s while from 2000 onwards the term self-management gained popularity, with a greater focus on long-term conditions and the trend towards more holistic models of care. Although self-management and self-care are often used interchangeably, a distinction between the two concepts can be made. Both can be considered in terms of a continuum, with self-care at one end as “normal activity” and self-management an extension of this. Self-management support is the assistance given to patients in order to encourage daily decisions that improve health-related behaviors and clinical outcomes. The chapter envisions these concepts on a continuum with one pole representing mobile health and the other self-care. It concludes that self-management support is the nexus of mobile health and self-care.
Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo
Authors: Xu Yitian , Huang Lu , Kirschman Jonathan L. , Vanover Daryll A. , Tiwari Pooja M. , Santangelo Philip J. , Shen Xiling , Russell David G.
Published: December 2018

Therapeutic strategies based on in vitro–transcribed mRNA (IVT) are attractive because they avoid the permanent signature of genomic integration that is associated with DNA-based therapy and result in the transient production of proteins of interest. To date, IVT has mainly been used in vaccination protocols to generate immune responses to foreign Ags. In this “proof-of-principle” study, we explore a strategy of combinatorial IVT to recruit and reprogram immune effector cells to acquire divergent biological functions in mice in vivo. First, we demonstrate that synthetic mRNA encoding CCL3 is able to recruit murine monocytes in a nonprogrammed state, exhibiting neither bactericidal nor tissue-repairing properties. However, upon addition of either Ifn-γ mRNA or Il-4 mRNA, we successfully polarized these cells to adopt either M1 or M2 macrophage activation phenotypes. This cellular reprogramming was demonstrated through increased expression of known surface markers and through the differential modulation of NADPH oxidase activity, or the superoxide burst. Our study demonstrates how IVT strategies can be combined to recruit and reprogram immune effector cells that have the capacity to fulfill complex biological tasks in vivo.
A comment on Critical issues of Emergency Medicine organization in Italy
Authors: Demicheli Vittorio
Published: December 2018

Not available.
Mycetoma in Timor-Leste and First Report of Nocardiosis
Authors: Townell Nicola , Locke Thomas , Gibbons Margaret , Murphy Dan , Francis Joshua , Nourse Clare
Published: December 2018

Mycetoma is a neglected tropical disease with an unknown global burden. Although considered endemic to South-east Asia, it has not previously been reported from Timor-Lest. We describe two cases in Timor-Leste, highlighting the challenges surrounding microbiological diagnosis and management shared by many low to middle-income countries. As characteristically described, both patients lived rurally and presented late with marked soft tissue involvement and multiple draining sinuses following a prolonged period of high morbidity. Nocardia brasiliensis, a beadedbranched, modified acid-fast, gram-positive bacilli, was isolated and confirmed by molecular testing in the first case. The causative organism in the second case could not be confirmed due to limited microbiological capabilities. Due to limited local laboratory capabilities, Nocardia spp. infection cannot be routinely confirmed in Timor- Leste. However, the microbiology laboratory is essential for the successful diagnosis and management of Mycetoma. In both cases, medical therapy alone resulted in cure and favorable outcomes, although supply of antibiotic remains an ongoing resource issue.
SALUTO DEL PRESIDENTE DELLâ€™ISTITUTO LOMBARDO
Authors: Beretta Silvio
Published: December 2018

Non disponibile.
Corrigendum: Service quality perceptions of campus-based food outlets
Authors: Eresia-Eke Chukuakadibia E. , Stephanou Monique A. , Swanepoel Rochelle
Published: December 2018

No abstract available.
Validation of rainfall data estimated by GPM satellite on Southern Amazon region
Authors: Santos Luiz Octavio Fabricio dos , Querino Carlos Alexandre Santos , Querino Juliane Kayse Albuquerque da Silva , Pedreira Junior Altemar Lopes , Moura Aryanne Resende de Melo , Machado Nadja Gomes , Biudes Marcelo Sacardi
Published: December 2018

Rainfall is a meteorological variable of great importance for hydric balance and for weather studies. Rainfall estimation, carried out by satellites, has increased the climatological dataset related to precipitation. However, the accuracy of these data is questionable. This paper aimed to validate the estimates done by the Global Precipitation Measurement (GPM) satellite for the mesoregion of Southern Amazonas State, Brazil. The surface data were collected by the National Water Agency – ANA and National Institute of Meteorology – INMET, and is available at both institutions’ websites. The satellite precipitation data were accessed directly from the NASA webpage. Statistical analysis of Pearson correlation was used, as well as the Willmott’s “d” index and errors from the MAE (Mean Absolute Error) and RMSE (Root Mean Square Error). The GPM satellite satisfactorily estimated the precipitation, once it had correlations above 73% and high Willmott coefficients (between 0.86 and 0.97). The MAE and RMSE showed values that varied from 36.50 mm to 72.49 mm and 13.81 mm to 71.76 mm, respectively. Seasonal rain variations are represented accordingly. In some cases, either an underestimation or an overestimation of the rain data was observed. In the yearly totals, a high rate of similarity between the estimated and measured values was observed. We concluded that the GPM-based multi-satellite precipitation estimates can be used, even though they are not 100% reliable. However, adjustments in calibration for the region are necessary and recommended.
Histopathological and hematological biomarkers in tambaqui Colossoma macropomum (Cuvier, 1816) from an environmental protection area of Maranhão, Brazil
Authors: Castro Jonatas Da Silva , Sodré Camilla Fernanda Lima , Souza Caroline Bogéa , Sousa Débora Batista Pinheiro , Carvalho Neta Raimunda Nonata Fortes
Published: December 2018

This study analyzed histopathological (gill lesions) and hematological (erythrocyte abnormalities) changes in tambaqui (Colossoma macropomum) in order to evaluate the water quality of fish farms in the Environmental Protection Area (EPA) of Maracanã, Maranhão, Brazil. Specimens of tambaqui were captured in two areas of EPA: A1) Serena Lagoon, and A2) River Ambude, in two seasonal periods, rainy and dry. For the hematological analyses, slides were made from the blood smear collected from the branchial arch of the fish. In the laboratory, the gills of each specimen were fixed in 10% formalin and maintained in 70% alcohol until the usual histological technique. The branchial changes were more frequent during the dry season in both areas. In the fish collection in A2, the following changes were noted: mucosal cells (78%), lamellar fusion (90%), lamellar disorganization (100%), lamellar narrowing (100%), and epithelial displacement (96%). In the fish collection in A1, the main lesions were: aneurysm (88%), dilation of the capillaries (82%), rupture of the capillaries (60%). In addition, nuclear alterations, such as binucleate cells (BC), cells with an evaginated nucleus (CEN) and cells with a lobulated carved nucleus (CLCN), were observed in the fish from both areas. The frequency of abnormalities was higher in the fish from A2 (74%) when compared to the fish from A1 (26%). In conclusion, we found that these alterations proved to be sensitive biomarkers capable of differentiating water quality and fish health status in the two systems in the Maracanã EPA.
Physico-chemical variability and heavy metal pollution of surface sediment in a non-channeled section of Dilúvio Stream (Southern Brazil) and the influence of channeled section in sediment pollution
Authors: Sodrzeieski Pedro Alexandre , Andrade Leonardo Capeleto de , Tiecher Tales , Camargo Flávio Anastácio de Oliveira
Published: December 2018

Dilúvio Stream flows through an area with a great population density in Porto Alegre, Southern Brazil. The anthropogenic influence in the surroundings impacted negatively the quality of the sediments of Dilúvio Stream and Lake Guaíba. This study evaluated the physico-chemical variability of surface sediments in a non-channeled section of Dilúvio Stream. Additionally, we compared the concentration of several heavy metals in this section with data from previous studies in the margins of Lake Guaíba near the outflow of Dilúvio Stream in order to evaluate the impact of urbanization on sediment pollution. The pH, bulk density, particle-size distribution, electrical conductivity, organic carbon, assimilable phosphorus, total nitrogen, mineralogical composition (X-ray diffractogram) and pseudo total concentration of several metals (Fe, Al, Ca, Mg, Na, K, Mn, Ba, Zn, V, As, Pb, Cu, Cr, Co, Ni, Cd, Mo, and Se) were evaluated. The results showed that the sediments in the non-channeled section of Dilúvio Stream are predominantly sandy, with heavy metal contents below the quality reference values. Quartz and feldspar predominated in all sites. The concentration of Zn, Pb, Cu, Cr, and Ni were lower than that observed in the margins of Lake Guaíba near the outflow of Dilúvio Stream, possibly due to pollution input throughout the channeled section. The Dilúvio Stream shows indications of an anthropogenic influence in the heavy metals concentration through the channeled area.
Towards a pseudoequational proof theory
Authors: Almeida Jorge , Klíma Ondřej
Published: December 2018

A new scheme for proving pseudoidentities from a given set

\Sigma

of pseudoidentities, which is clearly sound, is also shown to be complete in many instances, such as when

\Sigma

defines a locally finite variety, a pseudovariety of groups, more generally, of completely simple semigroups, or of commutative monoids. Many further examples for which the scheme is complete are given when

\Sigma

defines a pseudovariety V which is

\sigma

-reducible for the equation

x = y

, provided

\Sigma

is enough to prove a basis of identities for the variety of

\sigma

-algebras generated by V. This gives ample evidence in support of the conjecture that the proof scheme is complete in general.
Notes on computational-to-statistical gaps: predictions using statistical physics
Authors: Bandeira Afonso S. , Perry Amelia , Wein Alexander S.
Published: December 2018

In these notes we describe heuristics to predict computational-to-statistical gaps in certain statistical problems. These are regimes in which the underlying statistical problem is information-theoretically possible although no efficient algorithm exists, rendering the problem essentially unsolvable for large instances. The methods we describe here are based on mature, albeit non-rigorous, tools from statistical physics.
Explorando uma lista de transmissão para refletir sobre o conhecimento matemático para o ensino de análise combinatória
Authors: Andrade Fabiana Chagas de , Silva Elion Souza da , Santos Jefferson Araújo dos
Published: December 2018

O presente texto versa sobre o ensino de análise combinatória na educação básica, o qual, de acordo com a literatura de pesquisa em Educação Matemática, é geralmente de difícil compreensão por parte dos alunos (MOREIRA, ALVES, MAGINA, 2013) e um tema relevante para a formação de professores de matemática (BORBA, 2010). Buscamos refletir e discutir os resultados de uma atividade formativa proposta a professores de matemática do Ensino Médio. À luz das noções de Conhecimento Matemático para o Ensino (BALL, THAMES, PHELPS, 2008) e de Conhecimento Pedagógico do Conteúdo (SHULMAN, 1986), delineamos um percurso metodológico de cunho qualitativo, que consistiu no envio de um problema disparador – O Problema dos Diferentes Caminhos (ANDREESCU, FENG, 2013; SILVA, 2017) – a diferentes professores de matemática, através de uma lista de transmissão do aplicativo Whatsapp. Os sujeitos deveriam refletir sobre estratégias de resolução para os alunos em sala de aula. Assim, nosso objetivo foi analisar essas resoluções e discutir suas condutas segundo aspectos conceituais, didáticos e pedagógicos. A partir desse cenário, constatamos que os professores mobilizaram os diferentes aspectos do Conhecimento Matemático para o Ensino, descritos e categorizados por Ball, Thames e Phelps (2008). Por fim, ao simular a resolução do referido problema para os alunos, constatamos que os professores também puderam redimensionar (e refletir sobre) seus saberes, evidenciando que os mesmos aprendem e teorizam durante a sua prática.
Função quadrática: linguagem matemática e a representação de um pensamento
Authors: Austregésilo Thiel Afrânio , Das Neves Barbosa Thiago Henrique , Moretti Méricles Thadeu Thadeu
Published: December 2018

Este texto tem por objetivo promover uma reflexão mais profunda sobre o ensino e aprendizagem de ‘função quadrática’, ou seja, quais são os registros de representação elaborados pelos alunos e qual a sua compreensão dos elementos pertinentes ao tema. Inicialmente destaca algumas noções sobre a representação de um pensamento e em seguida faz a análise de questões elaboradas e aplicadas em duas turmas 1o. Ano do Ensino Médio. A pesquisa realizada reaviva a necessidade de que todo professor deve observar durante o processo de ensino e aprendizagem as dificuldades e o avanço cognitivo quanto às práticas matemáticas realizadas pelos estudantes. Na experiência, ficou evidente a dificuldade que os alunos têm para efetuar o tratamento e converter registros na linguagem natural, algébrica e gráfica. O que acontece, na verdade, é que a compreensão dos aprendizes fica limitada à forma de representação que eles conhecem e reproduzem.
Dê-me um mapa! A ordem sobre a terra
Authors: Machado Rosilene Beatriz , Flores Cláudia Regina
Published: December 2018

Este artigo tem por objetivo apresentar uma análise de como práticas de desenho e matemática foram (re)significadas nos domínios da cartografia, analisando-as em sua historicidade. Mais especificamente, colocamo-nos em seu campo de emergência, a fim de buscar os rastros históricos dos conteúdos escolares da disciplina de desenho, em suas relações com a matemática. Nosso propósito, assim, é analisar um dos fios do feixe de problematizações que deu as condições de possibilidade da emergência do desenho enquanto disciplina escolar, qual seja: a ordem sobre a terra.
Escrita-corpo-experiência e literatura: que pode o escrever (na pesquisa) [em educação matemática]?
Authors: Amaris Ruidiaz Paola Judith , Miarka Roger
Published: December 2018

Este artigo trata da escrita como potência criadora, como possibilidade que se abre a experimentar uma ação que envolve relações entre corpo e potência. Para isso, abordaram-se movimentos conceituais de uma pesquisa de doutorado por meio de uma escrita-experimentação. Pratica-se uma cartografia escrita junto à literatura, em que foi tecida uma narrativa de ficção, uma pequena história que ajudou a dar conta dos conceitos a serem trabalhados na pesquisa. Criou-se assim uma grafia do corpo que ajuda a problematizar um discurso de apropriações. Nesse sentido, assumiu-se uma escrita-corpo, escolhendo-se uma política de escrita-híbrida, que desfolhou conceitos que se engendraram no “fazer(-se) pesquisa”. Considera-se que a problematização aqui proposta possa auxiliar no caminho de muitos outros que consigam ser afetados por meio deste texto, para vislumbrar outro modo de fazer pesquisa, em que sejam as próprias palavras que possam dar força aos seus próprios instantes, e que o sujeito pesquisador se constitua ao escrever(-se).
Notas sobre ficção, histórias de vida e pesquisa em educação matemática: a propósito de o Impostor, de Javier Cercas
Authors: Fernandes Filipe Santos
Published: December 2018

“A realidade mata, a ficção salva” – afirma Javier Cercas ao propor um livro sobre a vida de Eric Marco, sindicalista espanhol que fingiu ter lutado na Guerra Civil Espanhola e vivenciado os horrores de um campo de concentração nazista. Articulando as inquietações de Javier Cercas para a escrita da obra e nosso interesse de relacionar a ficção, as histórias de vida e a pesquisa em Educação Matemática, buscamos neste texto evidenciar o conflitivo espaço da ficção e das histórias de vida na pesquisa e como determinados movimentos epistemológicos no campo da Educação Matemática permitiram uma reconfiguração desse espaço. Dessa discussão, propomos pensar os efeitos de uma estética ficcional na pesquisa em Educação Matemática, convidando-nos a um modo de fazer pesquisa em que a força, a fantasia, a imaginação, a memória e o amor pelas palavras participam intensamente da produção do conhecimento.
Atualidade de Baudelaire
Authors: Guyaux André
Published: December 2018

Trata-se, neste ensaio, de abordar a atualidade de Baudelaire a partir de sua percepção das noções de “modernidade”, “progresso” e do “mal”. Com efeito, o poeta estabelece, em sua definição de modernidade, uma dialética na qual triunfaria a eternidade na arte, a eternidade da arte. Ora, muitas vezes recorda-se apenas desta tese fundadora da parte relativa, que diz respeito ao transitório, ao fugidio. A ideia que Baudelaire tem do progresso é indissociável do sentido que dá ao mal, um progresso que é individual, que passa pela “diminuição do pecado original”, não pelo progresso material, este falso progresso celebrado em sua época (e atualmente).
Rumo à prosa: aspectos de um novo projeto de tradução dos Petits poèmes en prose, de Baudelaire
Authors: Veras Eduardo Horta Naasif
Published: December 2018

O artigo apresenta, em linhas gerais, as principais diretrizes que guiaram o trabalho de uma nova tradução dos Petits poèmes en prose, de Baudelaire, realizado por mim em parceria com Isadora Petry. Procuro mostrar, primeiramente, como o projeto do poeta francês de passagem para prosa demorou a ser compreendido mesmo pela crítica especializada, o que explica em grande parte o caráter poético das primeiras traduções brasileiras. Por outro lado, a radicalização do prosaísmo também não parece dar conta do desafio de traduzir essas “bagatelas laboriosas”, concebidas por Baudelaire como uma experiência poética essencialmente ambivalente. Sempre em diálogo com a Crítica, nossa tradução procurou enfrentar esse desafio da ambivalência, do qual este artigo aborda dois aspectos: o encontro da prosa com a poesia e a apropriação irônica e significativa do lugar-comum.
Epigrafía y onomástica en la "colonia latina" de "Carthago Nova"
Authors: De la Escosura Balbás M. Cristina
Published: December 2018

Desde su conquista por los romanos hasta mediados del s. I a.C. se ha considerado que Carthago Nova es una civitas stipendiaria. Sin embargo, esta condición jurídica es difícil de aceptar para una comunidad de tanta importancia estratégica y tan rica en recursos. El análisis de la onomástica documentada por sus habitantes en la epigrafía nos permite formular la hipótesis de una promoción colonial latina que permitiría conciliar no sólo las condiciones geoestratégicas del enclave, sino la constante aparición de estructuras de duo/tria nomina romanos que se registran en la ciudad y que no pueden sustraerse de las formalidades jurídicas que le son propias.
"Iustum matrimonium" e "ius conubii". Las uniones matrimoniales y el derecho de los latinos
Authors: Rodríguez Garrido Jacobo
Published: December 2018

El presente artículo pretende esclarecer la cuestión de los derechos matrimoniales de los Latini en época altoimperial, ya sean junianos o los que aquí denominaremos provinciales. Dicha tarea la realizaremos analizando la cuestión del ius conubii y su posible inclusión dentro de los derechos o capacidades propias de la latinidad, pero también poniendo especial interés en los mecanismos de promoción exclusivos de su status jurídico –a saber, el ius Latii y la anniculi probatio– y de sus efectos en las uniones matrimoniales previas. Con esto trataremos de demostrar la existencia de un elemento en común entre ambos tipos de latinos: un afán integrador.
Aquaculture Development and Education in Nepal: Potential and Challenges
Authors: Shrestha Abhimanyu , Balmi Sujita , Banmali Puja , Shrestha Nisha , Farquhar Samantha
Published: December 2018

In Nepal, the government has increased the support of fisheries and aquaculture activities to help increase economic productivity and well-being. However, while the potential for such activities are great, workforce is lacking due to education capacity. This essay voices the issues and frustrations of students who aspire to aid in the development of the fisheries and aquaculture sector of Nepal but face obstacles such as political instability, brain drain, and employment.
Language Barriers among Taiwanese National Champions
Authors: Chen Ying-Ling
Published: December 2018

The study investigated experiences of archery national champions regarding their use of English language at the international athlete village. The slowly growing recognition of the issue in the language barrier was discovered. Three female elite archery athletes were selected that met the criteria for national champion status was based upon previous experiences of competing in the international games. The use of semi-structure interview technique was implemented to be the main method of gathering research data. The study identified several language barriers to communication difficulties. The findings indicated language barriers become issues and had debilitating effect in communication through English language.
National defence training of public administration personnel in Poland
Authors: Grenda Bogdan , Soboń Andrzej
Published: December 2018

National defence training of public administration personnel can be broadly defined as a set
of activities undertaken at all levels of public administration, aimed at preparing staff to
perform official duties concerned with state defence. This paper opens with the presentation
of essential areas of national defence training. The subsequent section provides an overview
of implementations of national defence training at various levels of public administration
and at Higher Universities. The final part of this analysis describes the assumptions of
a new didactic framework of courses in defence for public administration and national
authorities at the Faculty of National Security of War Studies University in Warsaw.
Self-Determination and Creating a Society for All
Authors: Wehmeyer Michael L. Wehmeyer
Published: December 2018

Just societies – societies for all – are established based upon principles such as those articula¬ted in the United Nations Convention of the Rights of Persons with Disabilities, including “respect for inherent dignity, individual autonomy including the freedom to make one’s own choices, and independence of persons,” as stated first in the CRPD general principles. This article asserts that at the heart of achieving principles such as these and, ultimately, to achieve just and inclusive societies, we must focus on enabling and empowering people with disabilities to become self-determined. The article provides an overview of the use of the self-determination construct, its application in the disability context, its development, and briefly examines research pertaining to self-determination and youth and young adults with disabilities. The chapter concludes with a return to why self-determination is important to establish societies for all.
Potencjał osoby z niepełnosprawnością intelektualną. Implikacje dla edukacji i rehabilitacji społeczno-zawodowej
Authors: Parchomiuk Monika
Published: December 2018

W artykule przeanalizowano wybrane zagadnienia pokazujące potencjał osób z niepełnosprawnością intelektualną w zakresie realizowania ról społecznych. W analizie przeglądowej wykorzystano wyniki dostępnych badań podejmowanych w Polsce oraz za granicą, pokazujących m.in. udział tych osób w rolach opiekuńczych (wynikających ze stosunków rodzinnych, działalności wolontaryjnej i zawodowej) oraz funkcjonowanie w rolach rodzicielskich, partnerskich, zawodowych i self-adwokackich. Tego rodzaju zagadnienia, obrazujące potrzeby, możliwości, satysfakcję, ale również trudności niepełnosprawnych intelektualnie, są ważne zarówno dla procesu rodzinnej socjalizacji, jak i projektowania założeń edukacji i rehabilitacji.
Znaczenie spuścizny naukowej profesor Ireny Obuchowskiej dla współczesnej polskiej pedagogiki specjalnej
Authors: Twardowski Andrzej
Published: December 2018

Celem artykułu jest ukazanie tych elementów bogatego dorobku naukowego profesor Ireny Obuchowskiej, które nie tylko przyczyniły się do rozwoju polskiej pedagogiki specjalnej, lecz nadal mają dla niej istotne znaczenie. W pierwszej części artykułu przedstawiono koncepcję diagnozy pozytywnej oraz propozycje dotyczące teoretycznych podstaw pedagogiki specjalnej. Następnie przeanalizowano trzy koncepcje profesor Ireny Obuchowskiej dotyczące: autonomii, autorewalidacji i integracji społecznej osób niepełnosprawnych. W końcowej części artykułu udo¬kumentowano, że poglądy profesor Ireny Obuchowskiej na temat modelu postępowania rehabilitacyjnego oraz wspomagania rozwoju dziecka są nadal aktualne.
A Citizen’s Guide to the Second Amendment
Authors: Womble D. L.
Published: December 2018

Now—when a new generation is poised to enter the fray of the American debate over the meaning of the Second Amendment and how we might control the possession and use of firearms in our country—a review of the evolution of the firearms debate through the prism of historical documents, congressional debate and legislation, regulations by federal agencies, and statistical data seems useful. Such an undertaking is daunting and can never be exhaustive; yet, if we are to have a substantive conversation and find a reasonable path forward, citizens need to be armed with information.
Reseña de: Dubois, Y., Ornamentation et discours architectural de la villa romaine d’Orbe Boscéaz
Authors: Guiral Pelegrín Carmen
Published: December 2018

Reseña de: Dubois, Y.: Ornamentation et discours architectural de la villa romaine d’Orbe Boscéaz. (Cahiers d’Archéologie romande, 163, URBA II/1). Lausanne, 2016, 3 volúmenes. ISBN: 972-288028-163-2; ISSN: 1021-1713.
Reseña de: Hidalgo Prieto, Rafael (Coord.): Las Villas Romanas de la Bética
Authors: Fernández Ochoa Carmen
Published: December 2018

Reseña de Hidalgo Prieto, Rafael (Coord.): Las Villas Romanas de la Bética, vol. I y II, Ed. Universidad de Granada (ISBN: 978-84-338-6107-8), Universidad de Córdoba (ISBN: 978-84-9927-325-9), Universidad Pablo de Olavide (ISBN: 978-84-617-7532-3), Universidad de Sevilla (ISBN: 978-84-472-1861-5), Universidad de Málaga (ISBN: 978-84-9747-8298), Sevilla, 2016, 823 pgs.
Journal retractions in oncology – a bibliometric study
Authors: Pantziarka Pan , Meheus Lydie
Published: December 2018

Background. A number of recent high-profile cases have focused attention on scientific misconduct and other problematic issues with the peer review process. The retraction of journal publications is an important part of the scientific publishing process that serves to remove flawed articles, (including, but not limited to, fraudulent results), from the literature. To date there have been few formal studies of journal retractions in the area of oncology. Methods. This article outlines the results of a bibliometric study of journal retractions from 1983 to 2018. Results. Analysis shows that article lifetime – that is the time period from initial publication to ultimate retraction – has decreased in recent years. It also shows that retraction rate has also increased over the same period. The causes and context of these trends are discussed and reference made to the dangers of scientific misconduct in oncology.
Munc18-1 catalyzes neuronal SNARE assembly by templating SNARE association
Authors: Jiao Junyi , He Mengze , Port Sarah A , Baker Richard W , Xu Yonggang , Qu Hong , Xiong Yujian , Wang Yukun , Jin Huaizhou , Eisemann Travis J , Hughson Frederick M , Zhang Yongli
Published: December 2018

Sec1/Munc18-family (SM) proteins are required for SNARE-mediated membrane fusion, but their mechanism(s) of action remain controversial. Using single-molecule force spectroscopy, we found that the SM protein Munc18-1 catalyzes step-wise zippering of three synaptic SNAREs (syntaxin, VAMP2, and SNAP-25) into a four-helix bundle. Catalysis requires formation of an intermediate template complex in which Munc18-1 juxtaposes the N-terminal regions of the SNARE motifs of syntaxin and VAMP2, while keeping their C-terminal regions separated. SNAP-25 binds the templated SNAREs to induce full SNARE zippering. Munc18-1 mutations modulate the stability of the template complex in a manner consistent with their effects on membrane fusion, indicating that chaperoned SNARE assembly is essential for exocytosis. Two other SM proteins, Munc18-3 and Vps33, similarly chaperone SNARE assembly via a template complex, suggesting that SM protein mechanism is conserved.
The FZD7‐TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma
Authors: Tan Ming , Asad Mohammad , Heong Valerie , Wong Meng Kang , Tan Tuan Zea , Ye Jieru , Kuay Kuee Theng , Thiery Jean Paul , Scott Clare , Huang Ruby Yun‐Ju
Published: December 2018

Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD7 has emerged as a potential therapeutic target because it is capable of transducing both canonical and noncanonical Wnt signals. In this study, we investigated the regulatory pathway downstream of FZD7 and its functional roles. We found that FZD7 expression was crucial to the maintenance of the mesenchymal phenotype, anoikis resistance, and spheroid and tumor formation in ovarian cancer (OC). We identified TWIST1 as the crucial downstream effector of the FZD7 pathway. TWIST1, a basic helix loop helix transcription factor, is known to associate with mesenchymal and cancer stem cell phenotypes. Manipulating TWIST1 expression mimicked the functional consequences observed in the FZD7 model, and overexpression of TWIST1 partially rescued the functional phenotypes abolished by FZD7 knockdown. We further proved that FZD7 regulated TWIST1 expression through epigenetic modifications of H3K4me3 and H3K27ac at the TWIST1 proximal promoter. We also identified that the FZD7‐TWIST1 axis regulates the expression of BCL2, a gene that controls apoptosis. Identification of this FZD7‐TWIST1‐BCL2 pathway reaffirms the mechanism of anoikis resistance in OC. We subsequently showed that the FZD7‐TWIST1 axis can be targeted by using a small molecule inhibitor of porcupine, an enzyme essential for secretion and functional activation of Wnts. In conclusion, our results identified that the FZD7‐TWIST1 axis is important for tumorigenesis and anoikis resistance, and therapeutic inhibition results in cell death in OCs.
Extended Genetic Algorithm for OptimizedBIM‐Based Construction Scheduling
Authors: Faghihi Vahid , Reinschmidt Kenneth F. , Kang Julian H.
Published: December 2018

Construction project scheduling is one of the most important tools for project managers in the architecture, engineering, and construction (AEC) industry. Construction schedules allow project managers to track and manage the time, cost, and quality (i.e., the project management triangle) of projects. Developing project schedules is almost always troublesome, as it is heavily dependent on project planners' knowledge of work packages, on‐the‐job experience, planning capability, and oversight. Having a thorough understanding of the project geometries and their internal interacting stability relations plays a significant role in generating practical construction sequencing. On the other hand, the new concept of embedding all the project information into a three‐dimensional (3D) representation of a project (also known asbuilding information modelorBIM) has recently drawn the attention of the construction industry. It seems timely to use this source of project data for generating better construction schedules.

In this article, the authors demonstrate how to develop and extend the usage of the genetic algorithm (GA), not only to generate construction schedules, but also to optimize the outcome for different objectives (i.e., cost, time, and job‐site movements). The proposed methodology initially generates structurally stable construction schedules and then optimizes these schedules based on three distinct project management objectives. The basis for the GA calculations is the embedded data available in the BIM of the project, which should be provided as an input to the algorithm. By reading the geometric information in the 3D model and more specific information about the project and resources from the user, the algorithm results in various construction schedules. The output 4D animations and schedule quality scores can further help the user to find the most suitable construction schedules for the given project.
L
ongimicrobia
Authors: Pascual Javier , Genilloud Olga
Published: December 2018

Lon.gi.mi.cro'bi.a. N.L. neut. n.
Longimicrobium
type genus of the type order of the class; suff.
‐ia
ending to denote a class; N.L. neut. pl. n.
Longimicrobia
the class of the order
Longimicrobiales
.

Gemmatimonadetes / Longimicrobia

The delineation of the class
Longimicrobia
is defined based on the phylogenetic analysis of 16S rRNA gene sequences and corresponds to the former group 3 of the phylum
Gemmatimonadetes
. The class currently comprises the single order
Longimicrobiales
, which constitutes the type order and embraces only the chemoheterotrophic family
Longimicrobiaceae
.

DNA G + C content (mol%)
: 67.0 (HPLC).

Type order
:
Longimicrobiales
Pascual, García‐López, Bills and Genilloud 2016, 1984
VP
.
N
akamurellaceae
Authors: Chen Wen‐Feng , Tao Tian‐Shen
Published: December 2018

Na.ka.mu.rel.la.ce'ae. N.L. fem. n.
Nakamurella
type genus of the family; suff. ‐
aceae
ending to denote a family; N.L. fem. pl. n.
Nakamurellaceae
the
Nakamurella
family.

Actinobacteria / Actinobacteria / Frankiales / Nakamurellaceae

Cells are
Gram‐positive
,
non‐spore‐forming
,
spherical or irregular short‐rod‐shaped
, nonmotile
actinobacteria
. The microorganisms inhabit in activated sludge, soil, rock, fresh feces of insect katydid, and plant bark.
Aerobic chemoorganotroph
. The
growth rate is low
, and visible colonies on agar media appear after 7–10 days of incubation.
Catalase‐positive. Oxidase‐negative.
Contains

meso‐diaminopimelic acid in cell wall peptidoglycan. Major quinone is MK‐8(H
4
)

. Mannose, ribose, and rhamnose were found as the whole‐cell sugar patterns in four type strains except
Nakamurella endophytica
,
Nakamurella multipartita
, and
Nakamurella intestinalis
. Diphosphatidylglycerol (DPG), phosphatidylethanolamine (PE), phosphatidylinositol (PI), and unidentified aminophospholipids (APLs) are the major polar lipids. Common fatty acid is anteiso‐C
15:0
.

DNA G + C content (mol
%
)
: 64.6–74.3.

Type genus
:
Nakamurella
(Yoshimi et al. 1996) Tao, Yue, Chen and Chen 2004, 999
VP
(basonym: Microsphaera Yoshima et al. 1996, 524)
H
aloplasmataceae
Authors: Antunes André
Published: December 2018

Ha.lo.plas.ma.ta.ce'ae. N.L. neut. n.
Haloplasma
, type genus of the family; suff. ‐
aceae
, ending denoting an order; N.L. fem. pl. n.
Haloplasmataceae
, the
Haloplasma
family.

Firmicutes / Bacilli / Haloplasmatales / Haloplasmataceae

Pleomorphic cells, usually with contractile “tentacle‐like” protrusions. Motile by cellular contraction. Non‐spore‐forming. Strictly anaerobic. Strictly organotrophic. Denitrifying and fermentative. Only able to metabolize a very restricted range of carbon sources (
l
‐arabinose,
d
‐psicose, α‐ketobutyric acid, α‐ketoglutaric acid, and α‐ketovaleric acid). Cell wall is not detected. The predominant fatty acids (>10%) are C
16:0
, C
18:0
, C
18:1
ω9
c
, and summed feature 5 (most likely C
18:2
ω6,9
c
). The major polar lipids are phosphatidylglycerol and biphosphatidylglycerol. The major respiratory quinone is MK‐4. Phylogenetically a member of the phylum “Firmicutes,” the sole family of the order
Haloplasmatales
, and includes only the monospecific genus
Haloplasma
.

Otherwise, the description of the family is the same as for the genus
Haloplasma
.

DNA G
+
C content (mol%)
: 33.6 (HPLC), 33.0 (draft genome).

Type genus
:
Haloplasma
Antunes, Rainey, da Costa and Huber 2008, 2471
VP
(Effective publication: Antunes, Rainey, Wanner, Taborda, Pätzold, Nobre, da Costa and Huber 2008, 3586).
M
ethanosalsum
Authors: Sorokin Dimitry Y. , Merkel Alexander Y.
Published: December 2018

Me.tha.no.sal' sum
. N.L. pref.
methano
pertaining to methane; L. neut. part. adj.
salsum
salted, salty; N.L. neut. n.
Methanosalsum
the salty methane‐producing organism.

Euryarchaeota / Methanosarcinales / Methanosarcinales / Methanosarcinaceae / Methanosalsum

The genus
Methanosalsum
, classified within the family
Methanosarcinaceae
, order
Methanosarcinales
, consists of obligately anaerobic high salt‐tolerant and alkaliphilic euryarchaea that grow by methanogenic fermentation of C
1
‐methylated compounds. It inhabits inland, hypersaline alkaline lakes. The genus includes two species,
Methanosalsum zhilinae
, which is the type species of the genus, and
Methanosalsum natronophilum
.

DNA G
+
C content (mol%)
: 38–44.8 (
T
m
).

Type species
:
Methanosalsum zhilinae
(Mathrani, Boone, Mah, Fox and Lau 1988) Boone and Baker, 2002, 686
VP
(Effectively published: Boone and Baker 2001, 287; Basonym:
Methanohalophilus zhilinae
Mathrani, Boone, Mah, Fox and Lau 1988, 141).
G
lutamicibacter
Authors: Busse Hans‐Jürgen , Wieser Monika
Published: December 2018

Glu.ta.mi.ci.bac'ter. N.L. n.
acidum glutamicum
glutamic acid; N.L. masc. n.
bacter
a rod; N.L. masc, n.
Glutamicibacter
glutamic acid rod, referring to the presence of glutamic acid in the peptidoglycan interpeptide bridge.

Actinobacteria / Actinobacteria / Micrococcales / Micrococcaceae / Glutamicibacter

The genus
Glutamicibacter
contains the species
Glutamicibacter protophormiae, Glutamicibacter ardleyensis, Glutamicibacter arilaitensis, Glutamicibacter bergerei, Glutamicibacter creatinolyticus, Glutamicibacter halophytocola, Glutamicibacter mysorens, Glutamicibacter nicotianae, Glutamicibacter soli,
and
Glutamicibacter uratoxydans
. Cells are rod shaped when growing exponentially and are coccoid when reaching the stationary growth phase. The species of this genus share high 16S rRNA similarities (>96.9%). The peptidoglycan type is A4α (Lys–Ala–Glu; A11.35;
https://www.dsmz.de/?id=449
). The quinone system contains menaquinone MK‐8 and/or MK‐9 as major components. Major polar lipids are diphosphatidylglycerol, phosphatidylglycerol, and dimannosylglyceride. Except
G. halophytocola
, phosphatidylinositol is absent. Major fatty acid is anteiso‐C
15:0
. High amounts of iso‐C
15:0
, iso‐C
16:0
, anteiso‐C
17:0
, iso‐C
14:0
, and C
16:0
may also be present.

Representatives of the genus have been isolated from soil, wastewater reservoir sediment, sewage, Antarctic lake sediment, surfaces of cheeses, human urine, roots of
Limonium sinense
, and the fly
Protophormia terraenovae
.

DNA G + C content (mol%)
: 55–67.

Type species
:
Glutamicibacter protophormiae
(Stackebrandt, Fowler, Fiedler and Seiler 1984) Busse 2016, 28
VP
(
Arthrobacter protophormiae
, Stackebrandt, Fowler, Fiedler and Seiler 1984, 270).