bluuebunny/crossref_metadata_2025 huggingface dataset:
The U.S. Hispanic Flapper
Authors: Feu López Maria Montserrat
Published: November 2015

Mexican exile journalist Julio Arce's chronicles “Todo se arregla con money” (1924), “Cosas del Exhibition Day” (1924), and “La estenógrafa” (1925) are analyzed for their farcical portrayal of the 1920s Modern Girl, who symbolized immoral and consumerist modernity for Arce's readers. The article considers the context of previously unstudied journalistic genres from the era's leading U.S. Spanish-language newspapers, which display a range of comic forms that negatively represent the flapper's appearance and lifestyle. Beyond derisive entertainment, humor is aimed at influencing readers’ opinions about U.S. Hispanic women's gender and ethnic restrictions. The pelona was a popular topic in Spanish-language newspapers, and references to other entertainment industries from that era show that critical responses to flapperismo traveled across media, not only in the United States but also throughout the Americas.
Grammar and Grammaring: Toward Modes for English Grammar Teaching in China
Authors: Nan Chengyu
Published: November 2015

The value of grammar instruction in foreign language learning and teaching has been a focus of debate for quite some time, which has resulted in different views on grammar and grammar teaching as well as different teaching approaches based on different perspectives or in different language learning contexts. To explore some modes for grammar teaching in China on the basis of distinguishing grammar and grammaring, this research reviews briefly the current situations of grammar teaching at colleges in China and the various teaching modes adopted in different teaching contexts. Two teaching modes are suggested, linguistic mode and story-telling mode, which may activate inquiry learning and active learning. Linguistic mode, which emphasizes the dual features of grammar learning, is more reasoning-centered than knowledge-centered and is designed from linguistic and academic perspective for advanced learners. Story telling mode, which focuses on smooth communication in different contexts, is more skill-centered than rule-centered and is designed from social and communicative perspective for beginners. Exploring the modes for teaching grammar from linguistic and social perspectives will be a pilot study for inquiring other aspects of grammar teaching as well as for teaching grammar to the learners of other languages.
The Production of Red Wine from Black Jasmine Rice
Authors: Singkong Wachira
Published: November 2015

This research was conducted by employing local black jasmine rice grown in Kampaengphet, Thailand as raw material for red wine production. The author firstly studied black jasmine rice fundamental information, black jasmine starch and liquid starch. The 2 levels suitable proportions of black jasmine starch and clean water screened from 6 levels were 1:3 and 1:5 (w/w) prior to TSS adjustment to 20 and 25 oBrix. The mixture was 10 days fermented with Saccharomyces cerevisiae yeast before conducting aging at 0-4 oC for 8 weeks. It was found the alcohol content of red wine produced from black jasmine rice was 12% after 10 days of fermentation and TSS was depleted to 7.5-9.25 oBrix as pH which insignificantly reduced from 3.17-3.12 to 3.46-3.62. Antioxidant activity comparison between before and after fermentation of black jasmine wine indicated 85.14-89.06% and reduced to 80.26-86.54% respectively, due to the fermentation and aging process which reduced average 27-41% of anthocyanin even though total phenolic was average 10-54% increased. Proportion between black jasmine rice starch and clean water contained different TSS has significantly effected to wine’s sense quality at 95% of confidence level. Black jasmine rice wine produced from the black jasmine rice to clean water proportion of 1:5 with 25 oBrix TSS adjusted has obtained highest total hedonic score in the issues of color, clarity, sweetness, bitterness and significantly differed (P<0.05). All characteristics derived score were greater than 7 (moderate satisfied) except body characteristic.
Technology Acceptance Model, Organizational Commitment and Turnover Intention: A Conceptual Framework
Authors: Parvari Alireza , Anvari Roya , Mansor Nur Naha binti Abu , Jafarpoor Masoomeh , Parvari Maliheh
Published: November 2015

Information system is being implemented to improve job performance and facilitate employees’ work. However, implementing Information system has some negative impacts on employees and organization if employees do not accept it. Several previous studies investigated some consequences of information technology such as turnover intention and job satisfaction. This study provides a conceptual framework that shows other independent consequences of information system implementation. The model presented the impact of attitude towards using information technology on three components of organizational commitment (formative, normative and continuance). It also addresses the impact of attitude towards using information technology on turnover intention directly and via organizational commitment. Based on technology acceptance and its consequences, we develop a number of testable propositions that can guide to further research on work related outcome due to technology acceptance. Finally, we provide some recommendations for future research.
Perfiles y percepciones de género en violencia escolar
Authors: Velasco Gómez María José , Alvarez-González Beatriz
Published: November 2015

Esta investigación analiza las diferencias, por sexo, de adolescentes de 1º y 2º curso de Educación Secundaria Obligatoria (ESO), respecto a dos tipos de violencia: violencia reactiva y violencia instrumental (VR-VI). Se ha tratado de determinar la influencia de los sesgos culturales en la tolerancia de dichos comportamientos violentos, según el género de quien agrede. Constituyen la muestra 771 estudiantes de 5 Institutos públicos de la Comunidad de Madrid (CAM). Se han aplicado análisis cuantitativos sobre los datos del cuestionario “Violencia Reactiva e Instrumental y su relación con el Autocontrol en Adolescentes”. Se constata la necesidad de superar tópicos y sesgos culturales en la violencia escolar, para incrementar la eficacia de la prevención e intervención frente a la violencia y mejorar el clima de convivencia cotidiana en el aula.
Variabilité, identité spécifique et numérique des oeuvres contemporaines
Authors: Couture Francine
Published: November 2015

La réexposition d’oeuvres contemporaines sous la forme de la présentation de nouveaux exemplaires physiques d’une oeuvre conçue pour être unique questionne les notions de variabilité, d’identité spécifique et numérique de l’oeuvre d’art. Dans cet article, Couture étudie trois cas de figure propres à cette réalité : la production d’une réplique ou d’une copie d’exposition, l’exposition d’un élément d’une oeuvre, non pas comme un fragment, mais comme une oeuvre autonome, et enfin l’exemple particulier de l’actualisation d’un énoncé verbal qui est porteur des valeurs d’unicité et de singularité attribuées à l’oeuvre d’art. Elle conclut qu’il en résulte une transformation de l’institution muséale et de l’artiste engendrant notamment une redéfinition des rôles de chacun.
Le rôle de l’espace dans le musée et l’exposition
Authors: Gharsallah-Hizem Soumaya
Published: November 2015

L’espace dans l’expérience déambulatoire de la visite d’exposition est un élément significatif et sensible de la stratégie communicationnelle. Pourtant, fort peu de recherches se sont penchées sur l’espace à titre de médium de communication. Dans cet article, Soumaya Gharsallah-Hizem livre les résultats de son étude sur cette notion, jusque-là négligée par les chercheurs. S’appuyant sur l’analyse des expositions Avignon, un rêve que nous faisons tous, Trésors de la Méditerranée ainsi que celle du musée archéologique de Nice-Cimiez, l’auteure démontre comment l’espace opère au sein du processus de communication de l’exposition et de quelle manière il y contribue.
Muséologie et muséographie : la Tour de Babel ou les origines de la confusion
Authors: Aquilina Jannick Daniel
Published: November 2015

Suivant une approche historique, Jannick Daniel Aquilina recense les différentes occurrences du terme « muséologie » au fil des siècles et à travers les diverses cultures. Loin d’être arrêtée, la définition du mot varie dans le temps et dans l’espace et renvoie tour à tour à des activités fort différentes. En fait, l’évolution du mot « muséologie » peut être perçue, tel que l’explique l’auteur de cet article, comme la définition et la redéfinition constante de cette discipline universitaire.
La réactualisation des collections fermées, trois études de cas. Les collections du Isabella Stewart Gardner Museum, de Kettle's Yard et de la New Art Gallery Walsall
Authors: Lebeau Justine
Published: November 2015

Les collections fermées, conservées dans des demeures historiques, posent de véritables défis de renouvellement et d’actualisation à ses dirigeants. Ceux-ci doivent répondre aux nouvelles exigences des visiteurs en matière d’accueil et de visites muséales, tout en respectant leur devoir d’immuabilité envers les dispositions d’exposition de leurs collections. À partir de trois études de cas, soit les collections du Isabella Stewart Gardner Museum, de Kettle's Yard et de la New Art Gallery Walsall, Justine Lebeau détaille quatre stratégies de réactualisation de ce type de collections adoptées par ces institutions.
Un cabinet d’égyptologue au Siècle des Lumières : le cabinet d’histoire naturelle du docteur Gagnon au Musée Stendhal de Grenoble (France)
Authors: Rochas Joëlle
Published: November 2015

Dans Vie de Henry Brulard, Stendhal évoque la maison grenobloise de son grand-père, demeure devenue depuis le Musée Stendhal. Il y décrit et dessine le cabinet d’histoire naturelle type du Siècle des Lumières, celui-là même qu’aurait constitué le docteur Gagnon, son aïeul. En 2008, à la maison Gagnon, on amorce la reconstitution du cabinet. Joëlle Rochas, experte scientifique attitrée à cette reconstitution, rend compte dans cet article des différentes étapes de ce projet et des divers problèmes qui ont dû être réglés entre son idéation et sa réalisation, tout en révélant sa portée historique et signifiante.
Les musées traitant des migrations humaines : portrait d’une thématique muséale « tendance »
Authors: de Muys Geneviève
Published: November 2015

À l’ère de la mondialisation, la notion de territorialité nationale est en pleine mutation. Les identités se forgent au rythme des différentes vagues migratoires et de l’abolition des frontières. Cette nouvelle réalité se reflète au coeur du musée qui en fait l’un de ses thèmes d’exposition. Comment le musée traite-t-il cette thématique et de quelle manière justifie-t-il ses choix ? Geneviève de Muys propose dans cet article le résultat de ses recherches sur le sujet, révélant pourquoi la question migratoire est en phase de devenir une thématique muséale « tendance ».
Musealia des cultures de tradition orale
Authors: Soulier Virginie
Published: November 2015

À la suite du colonialisme, la redéfinition des relations entre Occidentaux et Autochtones engendre une réévaluation de la signification et de la présentation de leur patrimoine dans les musées européens et américains. Après quoi, une tendance à « l’artialisation » se profile, rejetant la polysémie de l’objet multiple et usuel au profit de l’objet unique présenté à la manière de l’oeuvre d’art. Face aux dérives possibles de cette tendance, Virginie Soulier démontre dans cet article que plusieurs musées adoptent a contrario une approche « plurivocale » et « authentique » où la multiplication des voix et des visions est privilégiée, plutôt que le seul aspect esthétique, propre à la sensibilité occidentale.
L’écrit dans l’exposition; Analyses et études de cas
Authors: Guillemette Laurie
Published: November 2015

De nos jours, les musées ne peuvent plus compter que sur les artefacts pour transmettre les contenus. Plusieurs outils de communication efficaces ont vu le jour dans les expositions pour pallier à ce problème et l’écrit est l’un de ces outils. Laurie Guillemette présente l’utilisation de l’écrit comme média. Son analyse s’appuie sur trois études de cas dont l’exposition itinérante Lire, toute une aventure.
Délibérer ou innover pour se réinventer : politiques des sciences et transformation des discours et projets institutionnels des centres de science et musées de la nature au Canada et en Ontario
Authors: Paquette Jonathan
Published: November 2015

Une décennie, c’est le temps qu’il aura fallu pour observer une évolution de l’attitude du public à l’égard des sciences et voir se manifester un intérêt de la part des gouvernements pour les musées et les centres de science. L’accès à l’information et l’éducation sont alors devenus des enjeux important pour ces institutions, favorisant ainsi la mise en place de nouveaux plans de communication. L’article qui suit fait une mise au point de la situation actuelle des choix institutionnels quant aux politiques, et aux discours de ces musées.
Collections universitaires dormantes : bilan et perspective
Authors: Bhérer-Vidal Lydia
Published: November 2015

Les collections universitaires sont riches et variées. Pourtant, de par leur caractère spécialisé, mais aussi suite à l’évolution des technologies et des nouvelles méthodes pédagogiques, elles sont de nos jours, rarement utilisées pour l’enseignement. Ce changement de vocation explique l’état actuel de dormance de ces collections universitaires. L’auteur s’attarde sur ces changements et questionne l’avenir de ce patrimoine, en proposant des solutions pour favoriser leur emploi.
Le Temps des Québécois : d’une intention communicationnelle à sa réception
Authors: Boursaud Audrey
Published: November 2015

Audrey Boursaud analyse l’exposition Le Temps des Québécois du Musée de la civilisation, dans le but de démontrer l’adéquation des intentions communicationnelles des concepteurs avec la perception et la recomposition que les visiteurs font de l’exposition grâce aux différents dispositifs scénographiques.
Poetes catalanes i poetes angleses als anys d’entreguerres. A propòsit d’una antologia ja feta i una per fer
Authors: Malé Jordi
Published: November 2015

Resum: L’objectiu principal d’aquest article és estudiar la poesia femenina catalana del període d’entreguerres aplicant dues metodologies: d’una banda, la literatura comparada, tot relacionant les escriptores catalanes amb les escriptores angleses del mateix període; i de l’altra banda, la crítica feminista, utilitzant alguns dels seus paradigmes. L’altre gran objectiu és reivindicar la qualitat d’algunes d’aquestes autores, com ara Roser Matheu, M. Teresa Vernet, Simona Gay, Maria Perpinyà i Cèlia Viñas, i també posar de manifest la importància que haurien de tenir en la història literària catalana contemporània.Paraules clau: poesia femenina, poesia catalana, poesia anglesa, període d’entreguerres, crítica literària.
Introducció monogràfic «La neologia lèxica: darreres recerques sobre el català»
Authors: Cabré Castellví Maria Teresa
Published: November 2015

Introducció al monogràfic sobre «La neologia lèxica: darreres recerques sobre el català» del número 59 (tardor 2015) de Caplletra. Revista Internacional de Filologia.
La resemantització com a recurs creatiu: la neologia cromàtica
Authors: Domènech Bagaria Ona , Estopà Bagot Rosa
Published: November 2015

Resum: El valor simbòlic que han adquirit els termes dels colors en les diferents cultures al llarg de la història explica que siguin un element recurrentment utilitzat per a la creativitat lèxica. En aquest treball abordem, des d’una perspectiva lingüística, un aspecte de l’estudi dels termes dels colors que ha estat poc tractat fins ara: el paper que juguen en la resemantització de les unitats lèxiques d’una llengua. Per fer-ho, partim, d’una banda, d’alguns dels conceptes fonamentals establerts des de l’antropologia lingüística, i de l’altra, dels supòsits teòrics de la semàntica cognitiva. Després de donar compte, en els primers apartats, dels conceptes teòrics fonamentals en què ens basem, analitzem un corpus de neologismes polilèxics lexicogràfics que contenen un mot de color, i acabem centrant-nos en l’anàlisi d’aquelles unitats que inclouen el mot verd, amb la finalitat de determinar els mecanismes semàntics i les relacions conceptuals que han motivat que, a partir del primer sentit de color, se n’hagin establert de nous.Paraules clau: neologia, neologia semàntica, resemantització, colors, metàfora, metonímia, lingüística cognitiva.
La neologia en societat: "verba sequuntur"
Authors: Freixa Judit
Published: November 2015

Resum: El punt de partida d’aquest article és de caràcter social: els neologismes apareixen per referir-se a les novetats del món i a altres necessitats expressives dels parlants. Atès que els parlants consideren seva la llengua i emeten judicis poc contrastats sobre les paraules noves, en aquest article es discuteixen alguns dels interrogants més habituals sobre aquest tema: què és un neologisme?, hi ha neologismes més neològics que d’altres?, per què apareixen neologismes?, són tots igualment necessaris?, com són els neologismes del català?, el català crea neologismes o només els copia d’altres llengües? La conclusió de l’article és que el català, com qualsevol altra llengua viva, té creativitat lèxica i acull neologismes de tots tipus: estables i efímers, nous i vells, voluntaris i involuntaris, correctes i incorrectes, denominatius i expressius, ben formats i transgressors.Paraules clau: neologia lèxica, neologicitat, societat, creativitat lèxica, interferència lèxica.
Josep Iborra, «Fuster, una declinació personal», València, Càtedra Joan Fuster / Publicacions de la Universitat de València, 2014, 290 pp.
Authors: Ortells Miralles Salvador
Published: November 2015

Ressenya sobre el llibre de Josep Iborra, Fuster, una declinació personal, València, Càtedra Joan Fuster / Publicacions de la Universitat de València, 2014, 290 pp.
Anna López Samaniego, «Las etiquetas discursivas: cohesión anafórica y categorización de entidades del discurso», EUNSA, 2014, 379 pp.
Authors: Ribera i Condomina Josep
Published: November 2015

Ressenya sobre el llibre d’Anna López Samaniego, Las etiquetas discursivas: cohesión anafórica y categorización de entidades del discurso, EUNSA, 2014, 379 pp.
Enric Bou, «La invenció de l’espai. Ciutat i viatge», València, Publicacions de la Universitat de València, 2013, 332 pp.
Authors: Salvador Vicent
Published: November 2015

Ressenya sobre el llibre d’Enric Bou, La invenció de l’espai. Ciutat i viatge, València, Publicacions de la Universitat de València, 2013, 332 pp.
Classes de gotas e volumes de aplicação na dessecação de coberturas vegetais
Authors: Almeida Dieimisson Paulo , Timossi Paulo César , Lima Suzete Fernandes , Silva Uadson Ramos , Reis Édesio Fialho dos
Published: November 2015

Objetivou-se verificar a influência das classes de gotas e volumes de aplicação na dessecação de Urochloa ruziziensis e Conyza sp. Para tal foi conduzido dois ensaios sob o delineamento de blocos casualizados, com quatro repetições, em esquema de parcelas subdivididas 2x4. As parcelas foram constituídas de classes de gotas (gotas muito finas e gotas ultra grossas) e as subparcelas por quatro volumes de aplicação (50, 100, 150 e 200 L ha-1). Para a dessecação foi utilizado o herbicida glyphosate nas doses de 0,975 e 1,3 kg de e.a. ha-1 para o controle das coberturas vegetais Urochloa ruziziensis e Conyza sp., respectivamente. O herbicida saflufenacil foi utilizado na dose de 49 g de i.a. ha-1 em associação ao glyphosate para o controle de Conyza sp. Na aplicação foi utilizado pulverizador pressurizado por CO2 com pontas de pulverização do modelo ATR 1,0 e AI 110015. Aos 5, 10, 15 e 20 dias após a aplicação (DAA) dos herbicidas foram realizadas avaliações visuais da porcentagem de controle da Urochloa ruziziensis e da desfolha no caso de Conyza sp. Aos 25 DAA foi realizada uma avaliação de porcentagem de rebrote de plantas de Conyza sp.. Conclui-se que a classe de gotas ultra grossa é eficiente na dessecação de Urochloa ruziziensis com volumes de até 50 L ha-1 enquanto que a classe de gotas muito fina diminui a eficácia com a redução do volume de aplicação. Constatou-se também que a redução do volume de aplicação aumenta a possibilidade de rebrotes na dessecação de Conyza sp.
Influência do herbicida glyphosate na comunidade de plantas daninhas na região agrícola de Rio Verde, Goiás
Authors: Santos Weverton Ferreira , Procópio Sérgio De Oliveira , Silva Alessandro Guerra da , Fernandes Marcelo Ferreira , Barroso Alberto Leão de Lemos
Published: November 2015

A crescente utilização do glyphosate no Brasil aumentou a pressão de seleção sobre as espécies de plantas daninhas tolerantes e resistentes a este herbicida. Este estudo objetivou avaliar a influência do padrão de utilização do glyphosate na dinâmica populacional das plantas daninhas na cultura da soja em trinta e cinco áreas amostrais de diferentes propriedades. Estas áreas foram classificadas quanto ao número de aplicações e quantidade de equivalente ácidos de glyphosate. Foi utilizado o método do quadrado-inventário nas trinta e cinco áreas amostrais na safra 2012/2013. Calcularam-se os parâmetros estruturais relativos de frequência, abundância e valor indicador do número indivíduos e biomassa seca da parte aérea. A representação gráfica das diferenças da composição florística, foi realizada pela técnica de non-metric multidimensional scaling, com distâncias de Sorensen. O teste multi response permutation procedures foi utilizado para testar hipóteses de diferenças nas composições florísticas. A ocorrência de espécies típicas de cada tratamento foi avaliada pelo valor indicador, utilizando-se o teste de Monte Carlo (p<0,05). A composição florística do número de plantas, diferiu entre áreas que utilizam padrões médios de glyphosate (seis aplicações ou 6001 a 8000 g ha-1 de equivalente ácido) em comparação com áreas de padrão muito baixo (quatro ou cinco aplicações ou 2000 a 4000 g ha-1). As espécies Gnaphalium coarctatum, Eugenias sp., Rumex acetosella e Spermacoce latifolia, Digitaria horizontalis, Urochloa decumbens, Panicum maximum, Gossypum hirsutum e Indigofera hirsuta apresentaram valor indicador significativo de ambientes com diferentes níveis de utilização de glyphosate. Diferentes padrões de utilização de glyphosate exerceram influência na composição florística das plantas daninhas nas áreas de soja avaliadas.
Manejo químico de Pilea microphylla em mudas de orquídeas
Authors: Klein Jeferson , Battistus André Gustavo , Hoffmann Vandir , Da Costa Neumárcio Vilanova , Kestring Débora , Bulegon Lucas Guilherme , Guimarães Vandeir Francisco
Published: November 2015

Espécies da família Orchidaceae são produzidas em larga escala para comercialização de suas flores. Entretanto, devido ao seu lento desenvolvimento, o substrato fica sujeito à infestação de plantas daninhas, como a brilhantina (Pilea microphylla). Assim, objetivou-se avaliar a seletividade de herbicidas à mudas de orquídeas do gênero Rhynchostylis ([Rhynchostylis gigantea Alba x Rhynchostylis gigantea] X Rhynchostylis gigantea Semi-Alba) e controle de P. microphylla. Adotou-se delineamento inteiramente casualizado, com quatro repetições por tratamento. Os herbicidas estudados foram: oxyfluorfen (0, 120, 240 e 480 g ha-1 i.a.), flumioxazin (0, 12,5, 25 e 40 g ha-1 i.a.), nicosulfuron (0, 20, 40 e 80 g ha-1 i.a.) e mesotrione (0, 96, 144 e 192 g ha-1 i.a.), com uma testemunha sem aplicação para cada molécula. Na ocasião da pulverização as plantas de orquídea apresentavam quatro folhas e 5 cm de altura, enquanto que a P. microphylla possuía 10 cm de altura. O nicosulfuron não controlou P. microphylla, enquanto o oxyfluorfen e o flumioxazin apresentaram eficiência de controle superior a 90% a partir dos 14 dias após a aplicação (DAA). A mesotrione demonstrou baixa capacidade de controle da infestante, atingindo em torno de 35% de eficiência aos 49 DAA. Todos os herbicidas foram seletivos às mudas do híbrido de Rhynchostylis. As moléculas oxyfluorfen e flumioxazin foram eficientes no controle da P. microphylla nos intervalos de doses testados.
Residual de metribuzin no solo sobre o crescimento do alho, cebola e feijão
Authors: Walperes Kellem Camila , Reis Marcelo Rodrigues dos , Carneiro Gabriella Daier Oliveira Pessoa , Rocha Bruno Henrique , Dias Roque De Carvalho , Melo Christiane Augusta Diniz , Gonçalves Clebson Gomes
Published: November 2015

O metribuzin é um herbicida amplamente utilizado para o controle de plantas daninhas em culturas como a soja, a batata e o tomate. No entanto, há suspeitas de intoxicações de culturas cultivadas em sucessão devido a resíduos desse produto no solo. Assim, objetivou-se avaliar o efeito de resíduos de metribuzin no solo sobre o crescimento de plantas de alho, cebola e feijão. Foram realizados três experimentos em casa de vegetação, no delineamento de blocos casualizados, com quatro repetições. Cada experimento correspondeu à cultura avaliada: alho, cebola ou feijão. Os tratamentos constituíram de diferentes concentrações de metribuzin no solo (0; 6; 12; 24; 48; 96; 144; 192; 240 e 480 ppb). Avaliou-se a intoxicação visual aos 7, 14, 21 e 28 dias após a emergência (DAE) das culturas e matéria seca aos 28 DAE. Constatou-se intoxicação das plantas de alho e feijão a partir da concentração de 96 ppb do metribuzin, com máxima injúria de 55 e 63%, respectivamente, aos 28 DAE. Na cultura da cebola os sintomas de intoxicação surgiram a partir de 40 ppb, sendo que a partir de 14 DAE foi observada morte das plantas nas concentrações de 240 a 480 ppb do herbicida. A massa da matéria seca do feijoeiro e da cebola foi reduzida pela presença do herbicida no solo, enquanto o crescimento do alho não foi afetado. Resíduos de metribuzin no solo podem inviabilizar a sucessão de culturas com alho, cebola ou feijão. Conclui-se que as plantas de alho, cebola e feijão são sensíveis aos resíduos de metribuzin no solo.
Low-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in Nigeria
Authors: Ojji Dike B. , Salam Abdul , Sani Mahmoud U. , Ogah Okechukwu S. , Schutte Aletta E. , Huffman Mark D. , Pant Rashmi , Ghosh Arpita , Dhurjati Rupasvi , Lakshmi Josyula K. , Ripiye Nanna. R. , Orji Ikechukwu A. , Kana Shehu A. , Abdussalam Tijjani , Olawumi Abdulgafar L. , Alfa Isiaka M. , Orimolade Olanike Allison , Ajayi Moses O. , Rodgers Anthony
Published: August 2024

Importance

With the high burden of hypertension in sub-Saharan Africa, there is a need for effective, safe and scalable treatment strategies.

Objective

To compare, among Black African adults, the effectiveness and safety of a novel low-dose triple-pill protocol compared with a standard-care protocol for blood pressure lowering.

Design and Setting

Randomized, parallel-group, open-label, multicenter trial conducted in public hospital–based family medicine clinics in Nigeria.

Participants

Black African adults with uncontrolled hypertension (≥140/90 mm Hg) who were untreated or receiving a single blood pressure–lowering drug.

Interventions

Participants were randomly allocated to low-dose triple-pill or standard-care protocols. The triple-pill protocol involved a novel combination of telmisartan, amlodipine, and indapamide in triple one-quarter, one-half, and standard doses (ie, 10/1.25/0.625 mg, 20/2.5/1.25 mg, and 40/5/2.5 mg), with accelerated up-titration. The standard-care protocol was the Nigeria hypertension treatment protocol starting with amlodipine (5 mg).

Main Outcomes and Measures

The primary effectiveness outcome was the reduction in home mean systolic blood pressure, and the primary safety outcome was discontinuation of trial treatment due to adverse events, both from randomization to month 6.

Results

The first participant was randomized on July 19, 2022, and the last follow-up visit was on July 18, 2024. Among 300 randomized participants (54% female; mean age, 52 years; baseline mean home blood pressure, 151/97 mm Hg; and clinic blood pressure, 156/97 mm Hg), 273 (91%) completed the trial. At month 6, mean home systolic blood pressure was on average 31 mm Hg (95% CI, 28 to 33 mm Hg) lower in the triple-pill protocol group and 26 mm Hg (95% CI, 22 to 28 mm Hg) lower in the standard-care protocol group (adjusted difference, −5.8 mm Hg [95% CI, −8.0 to −3.6]; P < .001]). At month 6, clinic blood pressure control (<140/90 mm Hg) was 82% vs 72% (risk difference, 10% [95% CI, −2% to 20%]) and home blood pressure control (<130/80 mm Hg) was 62% vs 28% (risk difference, 33% [95% CI, 22% to 44%]) in the triple-pill compared with the standard-care protocol group; these were 2 of 21 prespecified secondary effectiveness end points. No participants discontinued trial treatment due to adverse events.

Conclusions and Relevance

Among Black African adults with uncontrolled hypertension, a low-dose triple-pill protocol achieved better blood pressure lowering and control with good tolerability compared with the standard-care protocol.

Trial Registration

Pan African Clinical Trials Registry Identifier: PACTR202107579572114
Expert panel curation of 31 genes in relation to limb girdle muscular dystrophy
Authors: Mohan Shruthi , McNulty Shannon , Thaxton Courtney , Elnagheeb Marwa , Owens Emma , Flowers May , Nunnery Teagan , Self Autumn , Palus Brooke , Gorokhova Svetlana , Kennedy April , Niu Zhiyv , Johari Mridul , Maiga Alassane Baneye , Macalalad Kelly , Clause Amanda R. , Beckmann Jacques S. , Bronicki Lucas , Cooper Sandra T. , Ganesh Vijay S. , Kang Peter B. , Kesari Akanchha , Lek Monkol , Levy Jennifer , Rufibach Laura , Savarese Marco , Spencer Melissa J. , Straub Volker , Tasca Giorgio , Weihl Conrad C.
Published: August 2024

Objective

Limb girdle muscular dystrophies (LGMDs) are a group of genetically heterogeneous autosomal conditions with some degree of phenotypic homogeneity. LGMD is defined as having onset >2 years of age with progressive proximal weakness, elevated serum creatine kinase levels and dystrophic features on muscle biopsy. Advances in massively parallel sequencing have led to a surge in genes linked to LGMD.

Methods

The ClinGen Muscular Dystrophies and Myopathies gene curation expert panel (MDM GCEP, formerly Limb Girdle Muscular Dystrophy GCEP) convened to evaluate the strength of evidence supporting gene–disease relationships (GDR) using the ClinGen gene–disease clinical validity framework to evaluate 31 genes implicated in LGMD.

Results

The GDR was exclusively LGMD for 17 genes, whereas an additional 14 genes were related to a broader phenotype encompassing congenital weakness. Four genes (CAPN3, COL6A1, COL6A2, and COL6A3) were split into two separate disease entities, based on each displaying both dominant and recessive inheritance patterns, resulting in curation of 35 GDRs. Of these, 30 (86%) were classified as definitive, 4 (11%) as moderate, and 1 (3%) as limited. Two genes, POMGNT1 and DAG1, though definitively related to myopathy, currently have insufficient evidence to support a relationship specifically with LGMD.

Interpretation

The expert‐reviewed assertions on the clinical validity of genes implicated in LGMDs form an invaluable resource for clinicians and molecular geneticists. We encourage the global neuromuscular community to publish case‐level data that help clarify disputed or novel LGMD associations.
Nanocolumnar Metamaterial Platforms: Scaling Rules for Structural Parameters Revealed from Optical Anisotropy
Authors: Kilic Ufuk , Traouli Yousra , Hilfiker Matthew , Bryant Khalil , Schoeche Stefan , Feder Rene , Argyropoulos Christos , Schubert Eva , Schubert Mathias
Published: August 2024

Nanostructures represent a frontier where meticulous attention to the control and assessment of structural dimensions becomes a linchpin for their seamless integration into diverse technological applications. However, determining the critical dimensions and optical properties of nanostructures with precision still remains a challenging task. In this study, by using an integrative and comprehensive methodical series of studies, the evolution of the depolarization factors in the anisotropic Bruggeman effective medium approximation (AB‐EMA) is investigated. It is found that these anisotropic factors are extremely sensitive to the changes in critical dimensions of the nanostructure platforms. In order to perform a systematic characterization of these parameters, spatially coherent, highly‐ordered slanted nanocolumns are fabricated from zirconia, silicon, titanium, and permalloy on silicon substrates with varying column lengths using glancing angle deposition (GLAD). In tandem, broad‐spectral range Mueller matrix spectroscopic ellipsometry data, spanning from the near‐infrared to the vacuum UV (0.72–6.5 eV), is analyzed with a best‐match model approach based on the anisotropic Bruggeman effective medium theory. The anisotropic optical properties, including complex dielectric function, birefringence, and dichroism, are thereby extracted. Most notably, the research unveils a generalized, material‐independent inverse relationship between depolarization factors and column length. It is envisioned that the presented scaling rules will permit accurate prediction of optical properties of nanocolumnar thin films improving their integration and optimization for optoelectronic and photonic device applications. As an outlook, the highly porous nature and extreme birefringence properties of the fabricated columnar metamaterial platforms are further explored in the detection of nanoparticles from the cross‐polarized integrated spectral color variations.
Wide‐Bandgap RBa3(B3O6)3 (R = Nd, Sm, Tb, Dy, and Er) Single Crystals for Ultraviolet Nonlinear Optics
Authors: Sarker Saugata , Wang Yu , Benyacko Caeli , Guan Yingdong , Yoshida Suguru , Yennawar Hemant , He Jingyang , Mao Zhiqiang , Gopalan Venkatraman
Published: August 2024

Discovery of new materials with enhanced optical properties in the visible and UV‐C range can impact applications in lasers, nonlinear optics, and quantum optics. Here, the optical floating zone growth of a family of rare earth borates, RBa3(B3O6)3 (R = Nd, Sm, Tb, Dy, and Er), with promising linear and nonlinear optical (NLO) properties is reported. Although previously identified to be centrosymmetric, the X‐ray analysis combined with optical second harmonic generation (SHG) assigns the noncentrosymmetric P space group to these crystals. Characterization of linear optical properties reveals a direct bandgap of ≈5.61–5.72 eV and strong photoluminescence in both the visible and mid‐IR regions. Anisotropic linear and nonlinear optical characterization reveals both Type‐I and Type‐II SHG phase matchability, with the highest effective phase‐matched SHG coefficient of 1.2 pm V−1 at 800‐nm fundamental wavelength (for DyBa3(B3O6)3), comparable to β‐BaB2O4 (phase‐matched d22 ≈ 1.9 pm V−1). Laser‐induced surface damage threshold for these environmentally stable crystals is 650–900 GW cm−2, which is four to five times higher than that of β‐BaB2O4, thus providing an opportunity to pump with significantly higher power to generate about six to seven times stronger SHG light. Since the SHG arises from disorder on the Ba‐site, significantly larger SHG coefficients may be realized by “poling” the crystals to align the Ba displacements. These properties motivate further development of this crystal family for laser and wide bandgap NLO applications.
Dual Multiresonance Core Strategy Enable Efficient Pure Blue Organic Light‐Emitting Devices Based on Fluorene Linkages
Authors: Song Xiangan , Shen Shaogang , He Binghong , Zou Shengnan , Vaitusionak Aliaksei A. , Kostjuk Sergei V. , Wang Yafei , Wang Ying , Zhang Yong
Published: August 2024

Multiresonance thermally activated delayed fluorescence (MR‐TADF) emitters with high color purity in virtue of their inherent narrowband emission have received great interest in organic light‐emitting diodes (OLEDs). However, it remains a big challenge to develop the ultrapure blue MR‐TADF emitters with high efficiency. In this work, a novel “dual‐MR‐core” strategy is proposed by connecting two parent N‐B‐O‐skeletons with non‐conjugate 9‐position substituted fluorene linkages for high efficient deep‐blue MR‐TADF emitters, namely H‐FOBN and Me‐FOBN, which possess the highly twisted structure with suppressed aggregation. Finally, the vacuum‐deposited deep‐blue OLED exhibits excellent external quantum efficiency (EQE) of 25.1% with small full width at half maximum (FWHM) of 28 nm, as well as CIE of (0.14, 0.08). Furthermore, owing to enhanced solubility, the solution‐processed deep‐blue OLED based on Me‐FOBN shows EQE of 11.3%, with small FWHM of 32 nm and CIE of (0.14,0.09). These outstanding performances confirm that this “dual‐MR‐core” strategy provides a feasible approach to develop high efficient ultrapure blue MR‐TADF emitters.
Optically Ambidextrous Reflection Circularly Polarized Luminescence Film with High Dissymmetry Factor and On‐Demand Handedness
Authors: Jia Shengzhe , Yang Bingbing , Du Jing , Tao Tiantian , Zhang Jiayin , Tang Weiwei , Wang Jingkang , Gong Junbo
Published: August 2024

The self‐assembled cellulose nanocrystal (CNC) film has a left‐handed layered structure, which makes the reflection of right‐handed circularly polarized (CP) light a challenge. Herein, a nematic phase layer is designed and inserted into the chiral organization, to work as a half‐wave retarder and make the ambidextrous CP light reflection. The maximum reflectivity exceeds 80%, which breaks the 50% limitations of single‐direction light reflection and is the current maximum in all the reported CNC‐based films. This “sandwich‐like” structure displays different optical properties on both sides, displayed as the chromatism and the inversion of the circular dichroism signals. The dual CP light reflection and direction‐dependent optical phenomena are reserved in the synthesized circularly polarized luminescence (CPL) film, with the dissymmetry factor (glum) of −0.4245. However, this luminescent intensity and single‐direction emission are not enough in advanced optical systems. This work designs a triple CPL amplification path and develops the handedness inversion strategy, with the glum of −1.0551 and 0.4082. Then, the dual‐directional CPL emission films are designed, where the chiral optics can be switched on‐demand. Finally, the photonic crystal films are applied in the anti‐counterfeit and chiral superstructure induction.
Laser‐Induced Transformation of ZIF‐8 into Highly Luminescent N‐Doped Nanocarbons for Flexible Sensors
Authors: Tran Tuan‐Hoang , Garcia Aura , Kogolev Dmitry , Postnikov Pavel S. , Wang Ranran , Rodriguez Raul D. , Sheremet Evgeniya
Published: August 2024

Metal–organic frameworks (MOFs) like the zeolitic imidazolate framework (ZIF‐8) have a high surface area, tunable porosity, and robust thermal and chemical stability, making them attractive candidates for various applications. Here, a strategy is shown that spans that functionality and provides strong photoluminescence (PL) emission, unlocking ZIF‐8‐based materials for chemical and temperature sensors based on PL. The approach is based on laser processing that dramatically boosts the PL response of laser‐irradiated ZIF‐8 (LI ZIF‐8), achieving a 70‐fold increase in intensity relative to the pristine material. The PL characteristics of the irradiated material can be easily tuned by varying the laser power and irradiation time with in situ and real‐time spectroscopic analysis providing insights into the process dynamics. It is found that the observed PL enhancement is primarily due to the laser‐induced transformation of ZIF‐8 into nitrogen‐doped nanocarbons and ZnO nanostructures. The versatility of this laser processing approach is leveraged to create flexible electronics by integrating the LI ZIF‐8/nanocarbon architectures into thermoplastic polyurethane (TPU). The multifunctional composite material shows excellent performance as flexible electrodes for human‐body monitoring applications, as well as both temperature and flexure sensors with remarkable mechanical resilience.
PTC in the Polyenolate‐Mediated [10+2]‐Cycloaddition for the Synthesis of α,α‐Disubstituted Amino Acid Precursors
Authors: Dybowska Joanna , Przydacz Artur , Skrzyńska Anna , Albrecht Łukasz
Published: August 2024

The manuscript describes a formal [10+2] higher‐order cycloaddition between 2‐arylideneindan‐1‐ones and α‐alkylidene azlactones as higherene precursors and higherenofiles respectively. The reaction is realized under Brønsted‐base catalysis utilizing the phase transfer catalysis approach. The key intermediate is an isobenzofulvene‐derived polyenolate which acts as a 10‐electron component in the higher‐order cycloaddition. By using this strategy, a series of structurally diverse compounds containing a polycyclic hydrocarbon scaffold was prepared in 79–99% yields. In addition, the potential of the obtained [10+2]‐cycloadducts has been confirmed by transformations, including the synthesis of a highly‐valuable α,α‐disubstituted N‐protected α‐aminoester.
Resistive Switching Acceleration Induced by Thermal Confinement
Authors: Sarantopoulos Alexandros , Lange Kristof , Rivadulla Francisco , Menzel Stephan , Dittmann Regina
Published: August 2024

Enhancing the switching speed of oxide‐based memristive devices at a low voltage level is crucial for their use as non‐volatile memory and their integration into emerging computing paradigms such as neuromorphic computing. Efforts to accelerate the switching speed often result in an energy trade‐off, leading to an increase in the minimum working voltage. In this study, an innovative solution is presented: the introduction of a low thermal conductivity layer placed within the active electrode, which impedes the dissipation of heat generated during the switching process. The result is a notable acceleration in the switching speed of the memristive model system SrTiO3 by a remarkable factor of 103, while preserving the integrity of the switching layer and the interfaces with the electrodes, rendering it adaptable to various filamentary memristive systems. The incorporation of HfO2 or TaOx as heat‐blocking layers not only streamlines the fabrication process but also ensures compatibility with complementary metal‐oxide‐semiconductor technology.
A numerical comparison of heavy‐purge and dual‐reflux strategies in pressure swing adsorption for methane enrichment
Authors: Hu Guoping , Guo Yalou , Luo Jinbiao , Xiao Gongkui , Weh Roman , Li Kevin Gang , Qi Tao , Webley Paul A. , May Eric F.
Published: August 2024

Dual reflux pressure swing adsorption (DR‐PSA) has been regarded as a state‐of‐the‐art adsorption‐based process which can simultaneously obtain two streams of pure product gases with a narrow pressure window. However, the DR‐PSA has not yet been reported in industrial applications. Herein, a DR‐PSA and a heavy‐purge pressure vacuum swing adsorption (HP‐PVSA) were numerically investigated for the enrichment of 1%, 8% and 15% CH4 from N2 gas mixtures in pilot‐scale. Key separation indicators such as purity, recovery and energy cost of the two cycles were compared to analyze the limitations of the DR‐PSA process while scaling‐up. This study reveals the impact of heavy to feed (H/F) ratios on purity and recovery for both cycles and analyses the energy consumption of each process. For feed gas with 15% CH4, while DR‐PSA can achieve a slightly better purity and recovery (88.3% and 88.3%, respectively) compared to HP‐PVSA (87.5% and 80.3%, respectively), it also involves an order of magnitude higher energy consumption (181.6 versus 24.6 kJ/mol CH4 captured). DR‐PSA shows significantly superior performance than HP‐PVSA when the CH4 content in the raw feed gas is low. Under the investigated operating conditions, HP‐PVSA can only enrich 1% CH4 to 10% with 78.7% recovery while DR‐PSA can obtain 75.3% purity and 77.3% recovery. Results indicate that DR‐PSA exhibits superiority in enrichment of dilute gas, however, its high energy consumption, high capital expenditures and limitations in processing high throughput are the chief reasons hindering its industrial application.
Higher survival following transplantation with a mismatched unrelated donor with posttransplant cyclophosphamide‐based graft‐versus‐host disease prophylaxis than with double unit umbilical cord blood in patients with acute myeloid leukemia in first complete remission: A study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Authors: Baron Frédéric , Labopin Myriam , Versluis Jurjen , Vydra Jan , von dem Borne Peter A. , Nicholson Emma , Blaise Didier , Protheroe Rachel , Kulagin Alexander , Bulabois Claude Eric , Rovira Montserrat , Chevallier Patrice , Forcade Edouard , Byrne Jenny , Sanz Jaime , Ruggeri Annalisa , Mohty Mohamad , Ciceri Fabio
Published: August 2024

The best donor option for acute myeloid leukemia (AML) patients lacking an HLA‐matched donor has remained intensively debated. We herein report the results of a large retrospective registry study comparing hematopoietic cell transplantation (HCT) outcomes between double‐unit umbilical cord blood transplantation (dCBT, n = 209) versus 9/10 HLA‐matched unrelated donor (UD) with posttransplant cyclophosphamide (PTCy)‐based graft‐versus‐host disease (GVHD) prophylaxis (UD 9/10, n = 270) in patients with AML in first complete remission (CR1). Inclusion criteria consisted of adult patient, AML in CR1 at transplantation, either peripheral blood stem cells (PBSC) from UD 9/10 with PTCy as GVHD prophylaxis or dCBT without PTCy, transplantation between 2013 and 2021, and no in vivo T‐cell depletion. The 180‐day cumulative incidence of grade II‐IV acute GVHD was 29% in UD 9/10 versus 44% in dCBT recipients (p = .001). After adjustment for covariates, dCBT recipients had a higher non‐relapse mortality (HR = 2.35, 95% CI: 1.23–4.48; p = .01), comparable relapse incidence (HR = 1.12, 95% CI: 0.67–1.86; p = .66), lower leukemia‐free survival (HR = 1.5, 95% CI: 1.01–2.23; p = .047), and lower overall survival (HR = 1.66, 95% CI: 1.08–2.55; p = .02) compared with patients receiving UD 9/10 HCT. In summary, our results suggest that transplantation outcomes are better with UD 9/10 with PTCy‐based GVHD prophylaxis than with dCBT for AML patients in CR1. These data might support the use of UD 9/10 with PTCy‐based GVHD prophylaxis over dCBT in AML patients lacking an HLA‐matched donor.
Metal–Organic Frameworks for Electrocatalytic CO2 Reduction: From Catalytic Site Design to Microenvironment Modulation
Authors: Zhang Chengming , Lin Zhongyuan , Jiao Long , Jiang Hai‐Long
Published: August 2024

The electrochemical reduction of CO2 to high‐value carbon‐based chemicals provides a sustainable approach to achieving an artificial carbon cycle. In the decade, metal–organic frameworks (MOFs), a kind of porous crystalline porous materials featuring well‐defined structures, large surface area, high porosity, diverse components, easy tailorability, and controllable morphology, have attracted considerable research attention, serving as electrocatalysts to drive CO2 reduction. In this review, the reaction mechanisms of electrochemical CO2 reduction and the structure/component advantages of MOFs meeting the requirements of electrocatalysts for CO2 reduction are analyzed. After that, the representative progress for the precise fabrication of MOF‐based electrocatalysts for CO2 reduction, focusing on catalytic site design and microenvironment modulation, are systemically summarized. Furthermore, the emerging applications and promising research for more practical scenarios related to electrochemical CO2 conversion are specifically proposed. Finally, the remaining challenges and future outlook of MOFs for electrochemical CO2 reduction are further discussed.