bluuebunny/crossref_metadata_2025 huggingface dataset:
Data from Serum Endotoxins and Flagellin and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort
Authors: Kong So Yeon , Tran Hao Quang , Gewirtz Andrew T. , McKeown-Eyssen Gail , Fedirko Veronika , Romieu Isabelle , Tjønneland Anne , Olsen Anja , Overvad Kim , Boutron-Ruault Marie-Christine , Bastide Nadia , Affret Aurélie , Kühn Tilman , Kaaks Rudolf , Boeing Heiner , Aleksandrova Krasimira , Trichopoulou Antonia , Kritikou Maria , Vasilopoulou Effie , Palli Domenico , Krogh Vittorio , Mattiello Amalia , Tumino Rosario , Naccarati Alessio , Bueno-de-Mesquita H.B. , Peeters Petra H. , Weiderpass Elisabete , Quirós J. Ramón , Sala Núria , Sánchez María-José , Castaño José María Huerta , Barricarte Aurelio , Dorronsoro Miren , Werner Mårten , Wareham Nicholas J. , Khaw Kay-Tee , Bradbury Kathryn E. , Freisling Heinz , Stavropoulou Faidra , Ferrari Pietro , Gunter Marc J. , Cross Amanda J. , Riboli Elio , Bruce W. Robert , Jenab Mazda
Published: April 2023

Abstract
Background: Chronic inflammation and oxidative stress are thought to be involved in colorectal cancer development. These processes may contribute to leakage of bacterial products, such as lipopolysaccharide (LPS) and flagellin, across the gut barrier. The objective of this study, nested within a prospective cohort, was to examine associations between circulating LPS and flagellin serum antibody levels and colorectal cancer risk.

Methods: A total of 1,065 incident colorectal cancer cases (colon, n = 667; rectal, n = 398) were matched (1:1) to control subjects. Serum flagellin- and LPS-specific IgA and IgG levels were quantitated by ELISA. Multivariable conditional logistic regression models were used to calculate ORs and 95% confidence intervals (CI), adjusting for multiple relevant confouding factors.

Results: Overall, elevated anti-LPS and anti-flagellin biomarker levels were not associated with colorectal cancer risk. After testing potential interactions by various factors relevant for colorectal cancer risk and anti-LPS and anti-flagellin, sex was identified as a statistically significant interaction factor (Pinteraction < 0.05 for all the biomarkers). Analyses stratified by sex showed a statistically significant positive colorectal cancer risk association for men (fully-adjusted OR for highest vs. lowest quartile for total anti-LPS + flagellin, 1.66; 95% CI, 1.10–2.51; Ptrend, 0.049), whereas a borderline statistically significant inverse association was observed for women (fully-adjusted OR, 0.70; 95% CI, 0.47–1.02; Ptrend, 0.18).

Conclusion: In this prospective study on European populations, we found bacterial exposure levels to be positively associated to colorectal cancer risk among men, whereas in women, a possible inverse association may exist.

Impact: Further studies are warranted to better clarify these preliminary observations. Cancer Epidemiol Biomarkers Prev; 25(2); 291–301. ©2016 AACR.
Data from Coffee Drinking and Risk of Lung Cancer—A Meta-Analysis
Authors: Galarraga Vania , Boffetta Paolo
Published: April 2023

Abstract
Background: Previous epidemiologic results on coffee consumption and lung cancer risk have not been consistent. Furthermore, not all studies have addressed the potential role of tobacco as a confounder in this association. A meta-analysis was conducted to assess the effect of coffee consumption on lung cancer risk independent of tobacco use.

Methods: A systematic review and a meta-analysis based on random effects models were performed using studies from the PubMed and EMBASE databases, and the references from the retrieved articles. Included were 8 prospective cohorts and 13 case–control studies, which provided data for 19,892 cases and 623,645 non-cases, timeframe 1986–2015.

Results: The meta-relative risk (RR) for coffee drinking, not controlling for tobacco smoking, was 1.09 [95% confidence interval (CI), 1.00–1.19], the reference group was never drinkers. There was significant heterogeneity among the study results (Q = 84.39, I² = 75.1%, Pheterogeneity < 0.001). Among non-smokers, coffee was not associated with lung cancer risk (RR, 0.92; 95% CI, 0.75–1.10), the reference group was never drinkers. The meta-RR for 1 cup per day increase, unadjusted for smoking, was 1.04 (95% CI, 1.03–1.05); the corresponding RR for non-smokers was 0.95 (95% CI, 0.83–1.09).

Conclusions: The pooled estimates indicated that when the potential confounding effect from smoking is controlled for, coffee drinking does not appear to be a lung cancer risk factor. Further pooled analyses, with larger non-smokers population size, are encouraged to confirm these results.

Impact: This study illustrates that the association between coffee consumption and lung cancer can be confounded by tobacco smoking. Cancer Epidemiol Biomarkers Prev; 25(6); 951–7. ©2016 AACR.
Data from Obesity and the Incidence of Upper Gastrointestinal Cancers: An Ecological Approach to Examine Differences across Age and Sex
Authors: Arnold Melina , Colquhoun Amy , Cook Michael B. , Ferlay Jacques , Forman David , Soerjomataram Isabelle
Published: April 2023

Abstract
Background: Esophageal and gastric cancers differ in their epidemiology but have several risk factors in common. The aim of this study was to assess age and sex differences in the burden of esophageal and gastric cancers in the context of the global obesity epidemic.

Methods: Data from 50 countries were obtained from Cancer Incidence in Five Continents Volume X and GLOBOCAN 2012. Age-specific and age-standardized incidence rates of esophageal adenocarcinoma and squamous cell carcinoma (ESCC), as well as cardia (CGC) and noncardia (NCGC) gastric cancer, were estimated. Countries were grouped and analyzed according to their obesity prevalence.

Results: A gradient across quartiles of obesity prevalence was found for esophageal adenocarcinoma, with the highest incidence rates in high prevalence countries (ASR 3.0 vs. 0.8 per 100,000 in highest vs. lowest obesity quartiles, males). In contrast, for ESCC as well as for CGC and NCGC the reverse was true, with the highest rates observed in countries with the lowest obesity prevalence (ESCC, 2.2 vs. 11.5; CGC, 2.8 vs. 7.8; NCGC, 3.9 vs. 17.4 in highest vs. lowest obesity quartiles, males). Although for esophageal adenocarcinoma, sex and age differences in incidence were most pronounced in countries with a high prevalence of obesity, these differences were much smaller for the other cancer sites assessed.

Conclusions: Variation in obesity prevalence may partly explain age and sex differences in the incidence of esophageal adenocarcinomas.

Impact: Ecologic studies can help assess relationships between risk factors and cancer, and generate new hypotheses that may be pursued through more directed research. Cancer Epidemiol Biomarkers Prev; 25(1); 90–97. ©2015 AACR.
Data from Prostate Cancer Risk Allele Specific for African Descent Associates with Pathologic Stage at Prostatectomy
Authors: Whitman Eric J. , Pomerantz Mark , Chen Yongmei , Chamberlin Michael M. , Furusato Bungo , Gao Chunling , Ali Amina , Ravindranath Lakshmi , Dobi Albert , Sestrehenn Isabell A. , McLeod David G. , Srivastava Shiv , Freedman Matthew , Petrovics Gyorgy
Published: April 2023

Abstract
Purpose: A region on chromosome 8q24 was recently identified as a novel prostate cancer risk locus. Inherited variation in this region is associated with prostate cancer risk in the general population (21-58%), and specific alleles show a strong association in African-American men. This study was designed to evaluate associations between 8q24 risk alleles and clinical variables, such as pathologic stage, age at diagnosis, and recurrence, in a case series of African-American men.

Experimental Design: Peripheral blood DNA samples from 114 African-American men with prostate cancer, including 106 who had undergone radical prostatectomy, were genotyped for six single-nucleotide polymorphisms on three 8q24 regions. The presence of these single-nucleotide polymorphisms was compared with clinicopathologic and follow-up data after radical prostatectomy.

Results: The mean age of diagnosis and follow-up time were 57.4 (±8.9) years and 49.1 (±31.6) months, respectively. Patients carrying the Broad11934905 A risk allele, which is specific for African ancestry, were more likely to have a higher pathologic stage (pT3-4) than individuals with the wild type (odds ratio, 4.48; 95% confidence interval, 1.42-14.14; P = 0.011). A trend toward increased frequency of and shorter time to biochemical recurrence was noted in patients with this risk allele on Kaplan-Meier unadjusted survival analysis (P = 0.076).

Conclusions: The Broad11934905 polymorphism at 8q24, which is only found in people of African ancestry, is associated with an increase in non-organ-confined prostate cancer at prostatectomy. In addition, for those with this risk allele, there is a trend toward early biochemical recurrence that requires validation in larger studies. Cancer Epidemiol Biomarkers Prev; 19(1); 1–8
Data from Lichen Sclerosus: Incidence and Risk of Vulvar Squamous Cell Carcinoma
Authors: Bleeker Maaike C.G. , Visser Pascal J. , Overbeek Lucy I.H. , van Beurden Marc , Berkhof Johannes
Published: April 2023

Abstract
Background: The association between lichen sclerosus and vulvar squamous cell carcinoma (VSCC) has long been recognized, but large epidemiologic studies are lacking.

Methods: Data of women diagnosed with vulvar pathology in the Netherlands were retrieved from the Dutch Pathology Registry. All vulvar pathology reports of this historical cohort were reviewed to construct a research database, including 3,038 women with lichen sclerosus diagnosed between 1991 and 2011. The incidence rate of lichen sclerosus and the cumulative incidence of VSCC among women with lichen sclerosus were estimated.

Results: Between 1991 and 2011, the incidence rate of lichen sclerosus increased from 7.4 to 14.6 per 100,000 woman-years. The median age at time of lichen sclerosus diagnosis was 59.8 years and the cumulative VSCC incidence was 6.7%. The 10-year VSCC incidence in women with lichen sclerosus was associated with concurrent vulvar intraepithelial neoplasia (VIN; 18.8% in women with VIN and 2.8% in women without VIN) and age at time of lichen sclerosus diagnosis (5.9% in women of ≥70 years, 3% in women between 50 and 70 years, and 1.8% in women <50 years). The effects of presence of VIN and age remained significant in adjusted Cox regression analysis.

Conclusion: This historical cohort showed a nearly 100% increase in incidence of lichen sclerosus between 1991 and 2011. Concurrent VIN and age ≥70 years at time of lichen sclerosus diagnosis are important risk factors for vulvar cancer development.

Impact: The incidence of lichen sclerosus is rising and special attention is needed in particular in women with concurrent VIN because of their high risk of cancer. Cancer Epidemiol Biomarkers Prev; 25(8); 1224–30. ©2016 AACR.
Data from Overall and Abdominal Adiposity and Premenopausal Breast Cancer Risk among Hispanic Women: The Breast Cancer Health Disparities Study
Authors: John Esther M. , Sangaramoorthy Meera , Hines Lisa M. , Stern Mariana C. , Baumgartner Kathy B. , Giuliano Anna R. , Wolff Roger K. , Slattery Martha L.
Published: April 2023

Abstract
Background: Few studies in Hispanic women have examined the relation between adult body size and risk of premenopausal breast cancer defined by hormone receptor status.

Methods: The Breast Cancer Health Disparities Study pooled interview and anthropometric data from two large U.S. population-based case–control studies. We examined associations of overall and abdominal adiposity with risk of estrogen receptor– and progesterone receptor–positive (ER+PR+) and –negative (ER−PR−) breast cancer in Hispanic and non-Hispanic White (NHW) women, calculating ORs and 95% confidence intervals.

Results: Among Hispanics, risk of ER+PR+ breast cancer was inversely associated with measures of overall adiposity, including young-adult and current body mass index (BMI). Risk was substantially reduced among those with high (above the median) young-adult BMI and current overweight or obesity. The findings for overall adiposity were similar for Hispanics and NHWs. In the subset of Hispanics with data on genetic ancestry, inverse associations of current BMI, and weight gain with ER+PR+ breast cancer were limited to those with lower Indigenous American ancestry. For ER−PR− breast cancer, height was associated with increased risk, and young-adult BMI was associated with reduced risk. For all breast cancers combined, positive associations were seen for waist circumference, waist-to-hip ratio, and waist-to-height ratio in Hispanic women only.

Conclusions: Our findings of body size associations with specific breast cancer subtypes among premenopausal Hispanic women were similar to those reported for NHW women.

Impact: Adiposity throughout the premenopausal years has a major influence on breast cancer risk in Hispanic women. Cancer Epidemiol Biomarkers Prev; 24(1); 138–47. ©2014 AACR.

See related article by John et al., p. 128
Data from Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium
Authors: Toth Reka , Scherer Dominique , Kelemen Linda E. , Risch Angela , Hazra Aditi , Balavarca Yesilda , Issa Jean-Pierre J. , Moreno Victor , Eeles Rosalind A. , Ogino Shuji , Wu Xifeng , Ye Yuanqing , Hung Rayjean J. , Goode Ellen L. , Ulrich Cornelia M.
Published: April 2023

Abstract
Background: Epigenetic disturbances are crucial in cancer initiation, potentially with pleiotropic effects, and may be influenced by the genetic background.

Methods: In a subsets (ASSET) meta-analytic approach, we investigated associations of genetic variants related to epigenetic mechanisms with risks of breast, lung, colorectal, ovarian and prostate carcinomas using 51,724 cases and 52,001 controls. False discovery rate–corrected P values (q values < 0.05) were considered statistically significant.

Results: Among 162,887 imputed or genotyped variants in 555 candidate genes, SNPs in eight genes were associated with risk of more than one cancer type. For example, variants in BABAM1 were confirmed as a susceptibility locus for squamous cell lung, overall breast, estrogen receptor (ER)–negative breast, and overall prostate, and overall serous ovarian cancer; the most significant variant was rs4808076 [OR = 1.14; 95% confidence interval (CI) = 1.10–1.19; q = 6.87 × 10−5]. DPF1 rs12611084 was inversely associated with ER-negative breast, endometrioid ovarian, and overall and aggressive prostate cancer risk (OR = 0.93; 95% CI = 0.91–0.96; q = 0.005). Variants in L3MBTL3 were associated with colorectal, overall breast, ER-negative breast, clear cell ovarian, and overall and aggressive prostate cancer risk (e.g., rs9388766: OR = 1.06; 95% CI = 1.03–1.08; q = 0.02). Variants in TET2 were significantly associated with overall breast, overall prostate, overall ovarian, and endometrioid ovarian cancer risk, with rs62331150 showing bidirectional effects. Analyses of subpathways did not reveal gene subsets that contributed disproportionately to susceptibility.

Conclusions: Functional and correlative studies are now needed to elucidate the potential links between germline genotype, epigenetic function, and cancer etiology.

Impact: This approach provides novel insight into possible pleiotropic effects of genes involved in epigenetic processes. Cancer Epidemiol Biomarkers Prev; 26(6); 816–25. ©2017 AACR.
Data from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review
Authors: Wiggins Tom , Kumar Sacheen , Markar Sheraz R. , Antonowicz Stefan , Hanna George B.
Published: April 2023

Abstract
Gastroesophageal cancer has a rapidly increasing incidence worldwide and reliable biomarkers are urgently required to facilitate earlier diagnosis and improve survival. The aromatic amino acids tyrosine, phenylalanine, and tryptophan represent potential biomarkers and their relation to gastroesophageal cancer will be evaluated in this review. An electronic literature search was performed to identify all published research relating to the measurement of tyrosine, phenylalanine, or tryptophan in the biofluids or tissues of patients with gastroesophageal cancer. Sixteen studies were included in this systematic review. Six studies investigated serum concentrations, which all found decreased concentrations of these aromatic amino acids, except one study that found increased phenylalanine. Five studies reported increased concentrations within gastric content of these patients and two reported increased urinary concentrations. Tissue concentrations of these aromatic amino acids were increased in three studies. Tyrosine, phenylalanine, and tryptophan represent potential biomarkers of gastroesophageal cancer, and further research is necessary to definitively establish the mechanism responsible for altered concentrations of these compounds in patients with gastroesophageal cancer. Cancer Epidemiol Biomarkers Prev; 24(1); 32–38. ©2014 AACR.
Data from MicroRNA Classifier and Nomogram for Metastasis Prediction in Colon Cancer
Authors: Goossens-Beumer Inès J. , Derr Remco S. , Buermans Henk P.J. , Goeman Jelle J. , Böhringer Stefan , Morreau Hans , Nitsche Ulrich , Janssen Klaus-Peter , van de Velde Cornelis J.H. , Kuppen Peter J.K.
Published: April 2023

Abstract
Background: Colon cancer prognosis and treatment are currently based on a classification system still showing large heterogeneity in clinical outcome, especially in TNM stages II and III. Prognostic biomarkers for metastasis risk are warranted as development of distant recurrent disease mainly accounts for the high lethality rates of colon cancer. miRNAs have been proposed as potential biomarkers for cancer. Furthermore, a verified standard for normalization of the amount of input material in PCR-based relative quantification of miRNA expression is lacking.

Methods: A selection of frozen tumor specimens from two independent patient cohorts with TNM stage II–III microsatellite stable primary adenocarcinomas was used for laser capture microdissection. Next-generation sequencing was performed on small RNAs isolated from colorectal tumors from the Dutch cohort (N = 50). Differential expression analysis, comparing in metastasized and nonmetastasized tumors, identified prognostic miRNAs. Validation was performed on colon tumors from the German cohort (N = 43) using quantitative PCR (qPCR).

Results: miR25-3p and miR339-5p were identified and validated as independent prognostic markers and used to construct a multivariate nomogram for metastasis risk prediction. The nomogram showed good probability prediction in validation. In addition, we recommend combination of miR16-5p and miR26a-5p as standard for normalization in qPCR of colon cancer tissue–derived miRNA expression.

Conclusions: In this international study, we identified and validated a miRNA classifier in primary cancers, and propose a nomogram capable of predicting metastasis risk in microsatellite stable TNM stage II–III colon cancer.

Impact: In conjunction with TNM staging, by means of a nomogram, this miRNA classifier may allow for personalized treatment decisions based on individual tumor characteristics. Cancer Epidemiol Biomarkers Prev; 24(1); 187–97. ©2014 AACR.
Data from Tissue and Serum Mesothelin Are Potential Markers of Neoplastic Progression in Barrett's Associated Esophageal Adenocarcinoma
Authors: Rizk Nabil P. , Servais Elliot L. , Tang Laura H. , Sima Camelia S. , Gerdes Hans , Fleisher Martin , Rusch Valerie W. , Adusumilli Prasad S.
Published: April 2023

Abstract
Background: Mesothelin is overexpressed in several malignancies and is purportedly a specific marker of malignant transformation. In this pilot study, we investigated whether tissue and serum mesothelin are potential markers of neoplastic progression in Barrett's esophagus (BE) and in esophageal adenocarcinoma (EAC).

Methods: Mesothelin expression was retrospectively evaluated in normal, BE, and EAC tissue from surgically resected esophageal specimens (n = 125). In addition, soluble mesothelin-related peptide (SMRP) levels were measured in serum.

Results: Normal esophageal mucosa did not express mesothelin. BE tissue with high-grade dysplasia specifically expressed mesothelin, whereas BE tissue with low-grade or without dysplasia did not. Fifty-seven (46%) EAC tumors were positive for mesothelin. EAC tumors with BE expressed mesothelin more often than those without BE (58% vs. 35%, P = 0.01). SMRP levels were elevated in 70% of EAC patients (mean = 0.89 nmol/L; range: 0.03–3.77 nmol/L), but not in patients with acid reflux and/or BE.

Conclusions: Mesothelin is commonly expressed in BE-associated EAC. On the basis of this pilot study, a prospective study is under way to evaluate tissue and serum mesothelin which are potential markers of neoplastic progression in BE and in EAC (NCT01393483).

Impact: Current surveillance methods in Barrett's esophagus are invasive and neither cost-effective nor sensitive. This pilot study suggests that serum mesothelin is a marker of neoplastic transformation in BE and may provide a noninvasive method to improve identification of malignant transformation. Cancer Epidemiol Biomarkers Prev; 21(3); 482–6. ©2012 AACR.
Data from GPS-Based Exposure to Greenness and Walkability and Accelerometry-Based Physical Activity
Authors: James Peter , Hart Jaime E. , Hipp J. Aaron , Mitchell Jonathan A. , Kerr Jacqueline , Hurvitz Philip M. , Glanz Karen , Laden Francine
Published: April 2023

Abstract
Background: Physical inactivity is a risk factor for cancer that may be influenced by environmental factors. Indeed, dense and well-connected built environments and environments with natural vegetation may create opportunities for higher routine physical activity. However, studies have focused primarily on residential environments to define exposure and self-reported methods to estimate physical activity. This study explores the momentary association between minute-level global positioning systems (GPS)-based greenness exposure and time-matched objectively measured physical activity.

Methods: Adult women were recruited from sites across the United States. Participants wore a GPS device and accelerometer on the hip for 7 days to assess location and physical activity at minute-level epochs. GPS records were linked to 250 m resolution satellite-based vegetation data and Census Block Group-level U.S. Environmental Protection Agency (EPA) Smart Location Database walkability data. Minute-level generalized additive mixed models were conducted to test for associations between GPS measures and accelerometer count data, accounting for repeated measures within participant and allowing for deviations from linearity using splines.

Results: Among 360 adult women (mean age of 55.3 ± 10.2 years), we observed positive nonlinear relationships between physical activity and both greenness and walkability. In exploratory analyses, the relationships between environmental factors and physical activity were strongest among those who were white, had higher incomes, and who were middle-aged.

Conclusions: Our results indicate that higher levels of physical activity occurred in areas with higher greenness and higher walkability.

Impact: Findings suggest that planning and design policies should focus on these environments to optimize opportunities for physical activity. Cancer Epidemiol Biomarkers Prev; 26(4); 525–32. ©2017 AACR.

See all the articles in this CEBP Focus section, “Geospatial Approaches to Cancer Control and Population Sciences.”
Data from Cathepsin B Expression and Survival in Colon Cancer: Implications for Molecular Detection of Neoplasia
Authors: Chan Andrew T. , Baba Yoshifumi , Shima Kaori , Nosho Katsuhiko , Chung Daniel C. , Hung Kenneth E. , Mahmood Umar , Madden Karen , Poss Kirtland , Ranieri Audrey , Shue Daniel , Kucherlapati Raju , Fuchs Charles S. , Ogino Shuji
Published: April 2023

Abstract
Background and Aims: Proteases play a critical role in tumorigenesis and are upregulated in colorectal cancer and neoplastic polyps. In animal models, cathepsin B (CTSB)–activatable imaging agents show high enzyme activity within intestinal tumors.

Methods: We conducted a prospective cohort study of 558 men and women with colon cancer with tumors that were accessible for immunohistochemical assessment. We used Cox proportional hazards models, stratified by stage, to compute colon cancer–specific and overall mortality according to tumoral expression of CTSB.

Results: Among 558 participants, 457 (82%) had tumors that expressed CTSB (CTSB positive) and 101 (18%) had tumors that did not express CTSB (CTSB negative). CTSB expression was not associated with disease stage (P = 0.19). After a median follow-up of 11.6 years, there were 254 total and 155 colon cancer–specific deaths. Compared with participants with CTSB-negative tumors, participants with CTSB-positive tumors experienced a multivariate hazard ratio for colon cancer–specific mortality of 1.99 (95% confidence interval, 1.19-3.34) and overall mortality of 1.71 (95% confidence interval, 1.16-2.50). CTSB expression was independently associated with KRAS (P = 0.01) and BRAF mutation (P = 0.04), but not microsatellite instability status, CpG island methylator phenotype status, PIK3CA mutation, LINE-1 methylation, TP53 expression, or PTGS2 (cyclooxygenase-2) expression. Among 123 individuals with adenomas, 91% expressed CTSB.

Conclusions: As assessed by immunohistochemistry, CTSB is expressed in the vast majority of colon cancers, independent of stage, and is significantly associated with higher risk of colon cancer–specific and overall mortality.

Impact: These results support the potential of CTSB a target for image detection of neoplastic lesions in humans. Cancer Epidemiol Biomarkers Prev; 19(11); 2777–85. ©2010 AACR.
Supplementary Table S1 from Niche-Dependent Tumorigenic Capacity of Malignant Ovarian Ascites-Derived Cancer Cell Subpopulations
Authors: Katz Ehood , Skorecki Karl , Tzukerman Maty
Published: April 2023

Supplementary Table S1 from Niche-Dependent Tumorigenic Capacity of Malignant Ovarian Ascites-Derived Cancer Cell Subpopulations
Supplementary Data from ABT-888 Confers Broad In vivo Activity in Combination with Temozolomide in Diverse Tumors
Authors: Palma Joann P. , Wang Yi-Chun , Rodriguez Luis E. , Montgomery Debra , Ellis Paul A. , Bukofzer Gail , Niquette Amanda , Liu Xuesong , Shi Yan , Lasko Loren , Zhu Gui-Dong , Penning Thomas D. , Giranda Vincent L. , Rosenberg Saul H. , Frost David J. , Donawho Cherrie K.
Published: April 2023

Supplementary Data from ABT-888 Confers Broad In vivo Activity in Combination with Temozolomide in Diverse Tumors
Supplementary Movie S2 from Development and Characterization of a Novel In vivo Model of Carcinoid Syndrome
Authors: Jackson Lindsey N. , Chen L. Andy , Larson Shawn D. , Silva Scott R. , Rychahou Piotr G. , Boor Paul J. , Li Jing , DeFreitas Gilberto , Stafford W. Lane , Townsend Courtney M. , Evers B. Mark
Published: April 2023

Supplementary Movie S2 from Development and Characterization of a Novel In vivo Model of Carcinoid Syndrome
Supplementary Data from Longitudinal Cytokine Expression during IMRT for Prostate Cancer and Acute Treatment Toxicity
Authors: Christensen Eva , Pintilie Melania , Evans Kenneth R. , Lenarduzzi Michelle , Ménard Cynthia , Catton Charles N. , Diamandis Eleftherios P. , Bristow Robert G.
Published: April 2023

Supplementary Data from Longitudinal Cytokine Expression during IMRT for Prostate Cancer and Acute Treatment Toxicity
Supplementary Movie S1 from Development and Characterization of a Novel In vivo Model of Carcinoid Syndrome
Authors: Jackson Lindsey N. , Chen L. Andy , Larson Shawn D. , Silva Scott R. , Rychahou Piotr G. , Boor Paul J. , Li Jing , DeFreitas Gilberto , Stafford W. Lane , Townsend Courtney M. , Evers B. Mark
Published: April 2023

Supplementary Movie S1 from Development and Characterization of a Novel In vivo Model of Carcinoid Syndrome
CCR Translation for the Article from Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure
Authors: DePrimo Samuel E. , Huang Xin , Blackstein Martin E. , Garrett Christopher R. , Harmon Charles S. , Schöffski Patrick , Shah Manisha H. , Verweij Jaap , Baum Charles M. , Demetri George D.
Published: April 2023

CCR Translation for the Article from Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure
Supplementary Data from Use of Oral N-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Authors: Goodson Agnessa Gadeliya , Cotter Murray A. , Cassidy Pamela , Wade Mark , Florell Scott R. , Liu Tong , Boucher Kenneth M. , Grossman Douglas
Published: April 2023

Supplementary Data from Use of Oral N-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Authors: López-Vicente Laura , Armengol Gemma , Pons Berta , Coch Laura , Argelaguet Elisabet , Lleonart Matilde , Hernández-Losa Javier , de Torres Inés , Ramon y Cajal Santiago
Published: April 2023

Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Supplementary Table S3 from Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy
Authors: Wood Charles E. , Kaplan Jay R. , Fontenot M. Babette , Williams J. Koudy , Cline J. Mark
Published: April 2023

Supplementary Table S3 from Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy
Supplementary Table S2 from Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy
Authors: Wood Charles E. , Kaplan Jay R. , Fontenot M. Babette , Williams J. Koudy , Cline J. Mark
Published: April 2023

Supplementary Table S2 from Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy
Supplementary Data from Association of Breast Cancer Stem Cells Identified by Aldehyde Dehydrogenase 1 Expression with Resistance to Sequential Paclitaxel and Epirubicin-Based Chemotherapy for Breast Cancers
Authors: Tanei Tomonori , Morimoto Koji , Shimazu Kenzo , Kim Seung Jin , Tanji Yoshio , Taguchi Tetsuya , Tamaki Yasuhiro , Noguchi Shinzaburo
Published: April 2023

Supplementary Data from Association of Breast Cancer Stem Cells Identified by Aldehyde Dehydrogenase 1 Expression with Resistance to Sequential Paclitaxel and Epirubicin-Based Chemotherapy for Breast Cancers
Supplementary Figure S1 from Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy
Authors: Wood Charles E. , Kaplan Jay R. , Fontenot M. Babette , Williams J. Koudy , Cline J. Mark
Published: April 2023

Supplementary Figure S1 from Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy
Supplementary Data from Ligand-dependent Notch Signaling Is Involved in Tumor Initiation and Tumor Maintenance in Pancreatic Cancer
Authors: Mullendore Michael E. , Koorstra Jan-Bart , Li Yue-Ming , Offerhaus G. Johan , Fan Xing , Henderson Clark M. , Matsui William , Eberhart Charles G. , Maitra Anirban , Feldmann Georg
Published: April 2023

Supplementary Data from Ligand-dependent Notch Signaling Is Involved in Tumor Initiation and Tumor Maintenance in Pancreatic Cancer
Supplementary Data from Glycoprotein Nonmetastatic B Is an Independent Prognostic Indicator of Recurrence and a Novel Therapeutic Target in Breast Cancer
Authors: Rose April A.N. , Grosset Andrée-Anne , Dong Zhifeng , Russo Caterina , MacDonald Patricia A. , Bertos Nicholas R. , St-Pierre Yves , Simantov Ronit , Hallett Michael , Park Morag , Gaboury Louis , Siegel Peter M.
Published: April 2023

Supplementary Data from Glycoprotein Nonmetastatic B Is an Independent Prognostic Indicator of Recurrence and a Novel Therapeutic Target in Breast Cancer
Supplementary Figure Legends 1-2, Tables 1-4 from Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial–Mesenchymal Transition
Authors: Zhu Kai , Dai Zhi , Pan Qi , Wang Zheng , Yang Guo-Huan , Yu Lei , Ding Zhen-Bin , Shi Guo-Ming , Ke Ai-Wu , Yang Xin-Rong , Tao Zhong-Hua , Zhao Yi-Ming , Qin Yi , Zeng Hai-Ying , Tang Zhao-You , Fan Jia , Zhou Jian
Published: April 2023

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Supplementary Figure Legend from Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation
Authors: Ding Zhen-Bin , Hui Bo , Shi Ying-Hong , Zhou Jian , Peng Yuan-Fei , Gu Cheng-Yu , Yang Hua , Shi Guo-Ming , Ke Ai-Wu , Wang Xiao-Ying , Song Kang , Dai Zhi , Shen Ying-Hao , Fan Jia
Published: April 2023

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Supplementary Table 1, Figures 1-2 from A Phase 1 Dose Escalation, Pharmacokinetic, and Pharmacodynamic Evaluation of eIF-4E Antisense Oligonucleotide LY2275796 in Patients with Advanced Cancer
Authors: Hong David S. , Kurzrock Razelle , Oh Yun , Wheler Jennifer , Naing Aung , Brail Les , Callies Sophie , André Valérie , Kadam Sunil K. , Nasir Aejaz , Holzer Timothy R. , Meric-Bernstam Funda , Fishman Mayer , Simon George
Published: April 2023

PDF file - 69K
Supplementary Video from Specific PET Imaging of xC− Transporter Activity Using a 18F-Labeled Glutamate Derivative Reveals a Dominant Pathway in Tumor Metabolism
Authors: Koglin Norman , Mueller Andre , Berndt Mathias , Schmitt-Willich Heribert , Toschi Luisella , Stephens Andrew W. , Gekeler Volker , Friebe Matthias , Dinkelborg Ludger M.
Published: April 2023

MPG Movie file - 4626K, Y94-9392 H460 Tumor PET
Supplementary Figures 1-3 from Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
Authors: Gotink Kristy J. , Broxterman Henk J. , Labots Mariette , de Haas Richard R. , Dekker Henk , Honeywell Richard J. , Rudek Michelle A. , Beerepoot Laurens V. , Musters René J. , Jansen Gerrit , Griffioen Arjan W. , Assaraf Yehuda G. , Pili Roberto , Peters Godefridus J. , Verheul Henk M.W.
Published: April 2023

PDF file - 174K
Supplementary Data from Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis
Authors: Saini Sharanjot , Majid Shahana , Yamamura Soichiro , Tabatabai Laura , Suh Seong O. , Shahryari Varahram , Chen Yi , Deng Guoren , Tanaka Yuichiro , Dahiya Rajvir
Published: April 2023

Supplementary Figures S1-S2; Supplementary Data.
Supplementary Table 3, Figure Legends 1-5 from Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer
Authors: Sano Daisuke , Xie Tong-Xin , Ow Thomas J. , Zhao Mei , Pickering Curtis R. , Zhou Ge , Sandulache Vlad C. , Wheeler David A. , Gibbs Richard A. , Caulin Carlos , Myers Jeffrey N.
Published: April 2023

PDf file - 182K
Supplementary Figure 1 from Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer
Authors: Sano Daisuke , Xie Tong-Xin , Ow Thomas J. , Zhao Mei , Pickering Curtis R. , Zhou Ge , Sandulache Vlad C. , Wheeler David A. , Gibbs Richard A. , Caulin Carlos , Myers Jeffrey N.
Published: April 2023

PDf file - 161K
Supplementary Figure 3 from Copy Number Gain of 1q25 Predicts Poor Progression-Free Survival for Pediatric Intracranial Ependymomas and Enables Patient Risk Stratification: A Prospective European Clinical Trial Cohort Analysis on Behalf of the Children's Cancer Leukaemia Group (CCLG), Société Française d'Oncologie Pédiatrique (SFOP), and International Society for Pediatric Oncology (SIOP)
Authors: Kilday John-Paul , Mitra Biswaroop , Domerg Caroline , Ward Jennifer , Andreiuolo Felipe , Osteso-Ibanez Teresa , Mauguen Audrey , Varlet Pascale , Le Deley Marie-Cecile , Lowe James , Ellison David W. , Gilbertson Richard J. , Coyle Beth , Grill Jacques , Grundy Richard G.
Published: April 2023

PDF file - 57K, Kaplan-Meier progression-free survival (PFS) curves for ependymoma 1q25 gain across individual CNS9204, BBSFOP and CNS9904/RT cohorts.
Supplementary Figure Legends 1-4, Tables 1-4 from Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor
Authors: Zeng Zhaolei , Lin Huanxin , Zhao Xiaohui , Liu Guanglin , Wang Xi , Xu Ruihua , Chen Kun , Li Jun , Song Libing
Published: April 2023

PDF file - 115K
Supplementary Figure 7 from Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor
Authors: Zeng Zhaolei , Lin Huanxin , Zhao Xiaohui , Liu Guanglin , Wang Xi , Xu Ruihua , Chen Kun , Li Jun , Song Libing
Published: April 2023

PDF file - 165K, FOXO1 plays an important role in GOLPH3 mediated-proliferation
Supplementary Figure Legend 1 from Phase II, Open-Label, Randomized Trial of the MEK1/2 Inhibitor Selumetinib as Monotherapy versus Temozolomide in Patients with Advanced Melanoma
Authors: Kirkwood John M. , Bastholt Lars , Robert Caroline , Sosman Jeff , Larkin James , Hersey Peter , Middleton Mark , Cantarini Mireille , Zazulina Victoria , Kemsley Karin , Dummer Reinhard
Published: April 2023

PDF file - 34K
Supplementary Figure 1 from Phase II, Open-Label, Randomized Trial of the MEK1/2 Inhibitor Selumetinib as Monotherapy versus Temozolomide in Patients with Advanced Melanoma
Authors: Kirkwood John M. , Bastholt Lars , Robert Caroline , Sosman Jeff , Larkin James , Hersey Peter , Middleton Mark , Cantarini Mireille , Zazulina Victoria , Kemsley Karin , Dummer Reinhard
Published: April 2023

PDF file - 160K
Supplementary Table 1 from Pretargeted Radioimmunotherapy Using Genetically Engineered Antibody-Streptavidin Fusion Proteins for Treatment of Non-Hodgkin Lymphoma
Authors: Park Steven I. , Shenoi Jaideep , Frayo Shani M. , Hamlin Donald K. , Lin Yukang , Wilbur D. Scott , Stayton Patrick S. , Orgun Nural , Hylarides Mark , Buchegger Franz , Kenoyer Aimee L. , Axtman Amanda , Gopal Ajay K. , Green Damian J. , Pagel John M. , Press Oliver W.
Published: April 2023

PDF file - 52K
Supplementary Figures 1-5, Tables 1-6 from Copy Number Aberrations in Benign Serous Ovarian Tumors: A Case for Reclassification?
Authors: Hunter Sally M. , Anglesio Michael S. , Sharma Raghwa , Gilks C. Blake , Melnyk Nataliya , Chiew Yoke-Eng , deFazio Anna , Longacre Teri A. , Huntsman David G. , Gorringe Kylie L. , Campbell Ian G.
Published: April 2023

PDF file - 409K
Supplementary Table 1 from ON 01910.Na Is Selectively Cytotoxic for Chronic Lymphocytic Leukemia Cells through a Dual Mechanism of Action Involving PI3K/AKT Inhibition and Induction of Oxidative Stress
Authors: Chapman Colby M. , Sun Xiameng , Roschewski Mark , Aue Georg , Farooqui Mohamed , Stennett Lawrence , Gibellini Federica , Arthur Diane , Pérez-Galán Patricia , Wiestner Adrian
Published: April 2023

PDF file - 71K
Supplementary Figure 3 from Universal Cancer Peptide-Based Therapeutic Vaccine Breaks Tolerance against Telomerase and Eradicates Established Tumor
Authors: Dosset Magalie , Godet Yann , Vauchy Charline , Beziaud Laurent , Lone Yu Chun , Sedlik Christine , Liard Christelle , Levionnois Emeline , Clerc Bertrand , Sandoval Federico , Daguindau Etienne , Wain-Hobson Simon , Tartour Eric , Langlade-Demoyen Pierre , Borg Christophe , Adotévi Olivier
Published: April 2023

PDF file - 38K, Comparison of T-cell help mediated by UCP2 and a HTLV-1 Tax-derived peptide on self/TERT pY988 specific CTL response
Supplementary Figure 2 from Universal Cancer Peptide-Based Therapeutic Vaccine Breaks Tolerance against Telomerase and Eradicates Established Tumor
Authors: Dosset Magalie , Godet Yann , Vauchy Charline , Beziaud Laurent , Lone Yu Chun , Sedlik Christine , Liard Christelle , Levionnois Emeline , Clerc Bertrand , Sandoval Federico , Daguindau Etienne , Wain-Hobson Simon , Tartour Eric , Langlade-Demoyen Pierre , Borg Christophe , Adotévi Olivier
Published: April 2023

PDF file - 65K, UCP2 and UCP4 peptides increase self/TERT pY572 specific CTL responses
Supplementary legend from Anticancer Effects of Niclosamide in Human Glioblastoma
Authors: Wieland Anja , Trageser Daniel , Gogolok Sabine , Reinartz Roman , Höfer Heike , Keller Mihaela , Leinhaas Anke , Schelle Ramona , Normann Sabine , Klaas Lil , Waha Andreas , Koch Philipp , Fimmers Rolf , Pietsch Torsten , Yachnis Anthony T. , Pincus David W. , Steindler Dennis A. , Brüstle Oliver , Simon Matthias , Glas Martin , Scheffler Björn
Published: April 2023

Supplementary legend
Supplementary Figure 1 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 204KB, Panel A: Representative reactivity of anti-B7-H3 mAb BRCA84D with frozen tissue sections of prostate, breast, colon, lung, gastric and renal cancer. Panel B: Reactivity of anti-B7-H3 mAb BRCA69D on formalin-fixed paraffin embedded normal human spleen and lymph node tissues.
Supplementary Figure Legend from Phase I Trial of a Glypican-3–Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival
Authors: Sawada Yu , Yoshikawa Toshiaki , Nobuoka Daisuke , Shirakawa Hirofumi , Kuronuma Toshimitsu , Motomura Yutaka , Mizuno Shoichi , Ishii Hiroshi , Nakachi Kohei , Konishi Masaru , Nakagohri Toshio , Takahashi Shinichiro , Gotohda Naoto , Takayama Tadatoshi , Yamao Kenji , Uesaka Katsuhiko , Furuse Junji , Kinoshita Taira , Nakatsura Tetsuya
Published: April 2023

PDF file, 49KB.
Supplementary Figure 1 from In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate
Authors: Chuang Chih-Hung , Chuang Kuo-Hsiang , Wang Hsin-Ell , Roffler Steve R. , Shiea Jen-taie , Tzou Shey-Cherng , Cheng Ta-Chun , Kao Chien-Han , Wu Shih-Yen , Tseng Wei-Lung , Cheng Chiu-Min , Hou Ming-Feng , Wang Ju-Ming , Cheng Tian-Lu
Published: April 2023

PDF file - 866K
Supplementary Table 2 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 95K, DFS analysis with COX model.
Supplementary Figure 2 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 359K, OS and DFS analysis of chemotherapy on all patients.
Supplementary Figure 8 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 215K, Supplementary Figure S8: An association between increased level of MDA-9 mRNA expression and the development of therapeutic resistance and stable UCC was also evident in datasets available at TCGA database (TCGA_BLCA_SDCBP)
Supplementary Figures 1-2 from A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas
Authors: Kummar Shivaani , Ji Jiuping , Morgan Robert , Lenz Heinz-Josef , Puhalla Shannon L. , Belani Chandra P. , Gandara David R. , Allen Deborah , Kiesel Brian , Beumer Jan H. , Newman Edward M. , Rubinstein Larry , Chen Alice , Zhang Yiping , Wang Lihua , Kinders Robert J. , Parchment Ralph E. , Tomaszewski Joseph E. , Doroshow James H.
Published: April 2023

PDF file - 118K
Supplementary Figure 1 from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 74K, CSS by mutation type (missense vs truncating) in the MSKCC and TCGA cohorts.
Supplementary Authors' List from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 101K, TCGA Author list.
Supplementary Tables S1-8 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Tables S1-8:Table S1. Characteristics of the HNSCC cell lines Table S2. Characteristics of the MSCC cell lines with germline mutations in p53 pathway genes Table S3. Human kinome (713 kinases) Sigma Table S4. Murine kinome (572 kinases) Ambion Table S5. Interspecies kinome (508 kinases) Table S6. Primary validation siRNAs Table S7. Secondary validation siRNAs Table S8. Interspecies kinase targets selected for validation
Supplementary Table Legends from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Supplementary Table Legends
Supplementary Figure Legend from Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands
Authors: Chan Wing Keung , Kung Sutherland May , Li Ying , Zalevsky Jonathan , Schell Sarah , Leung Wing
Published: April 2023

PDF file - 65K
Supplementary Figure S1 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Figure S1. Plate layout for both primary validation screen and secondary assay
Supplementary Table S3 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Table S3 - PDF file 156K, Toxicities observed in ovarian cancer subjects following OCDC administrations