bluuebunny/crossref_metadata_2025 huggingface dataset:
Szkoła różnorodna kulturowo w Polsce. Doświadczenia bydgoskich nauczycieli w pierwszym okresie wojny w Ukrainie
Authors:   Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Grzybowski Przemysław P.
Published: November 2023

The article describes the experiences of Bydgoszcz teachers working in culturally diverse schools in the first period of the war in Ukraine (from February 24 to April 22, 2022). The basis of the article is the analysis of the statements provided by the participants of the conference “A Ukrainian student in the Polish education system. How to help teachers create a multicultural learning environment?” organized at the Kazimierz Wielki University, by its Department of Didactics and Studies on Culture of Education and the Kuyavian-Pomeranian Centre for Teacher Education in Bydgoszcz. The statements presented in the article concern the experience of eighty teachers from Bydgoszcz schools of various levels as well as academics, doctoral students and students working in educational institutions. The article is a contribution to the methodical trend of intercultural pedagogy. It contains practical tips on the work of teachers in culturally diverse classes, developed on the basis of current statements provided by people taking care of refugees from Ukraine.
Sedentary behavior and physical activity: barriers and facilitators for active behavior during the COVID-19 pandemic
Authors: Monteiro Fernanda Castro , Plácido Jessica , Silva Felipe de Oliveira , Lima Juliana Dias de , Schuch Felipe Barreto , Ward Philip B. , Deslandes Andrea Camaz
Published: November 2023

ABSTRACT Objectives: The objectives of the present study were to assess sedentary behavior and physical activity levels before and during the COVID-19 pandemic in healthy individuals and in those with self-reported diagnosis of anxiety and/or depression, and also identify facilitators and barriers to physical activity in these populations. Methods: This is a cross-sectional survey based on a self-report questionnaire applied during the COVID-19 pandemic period. Results: In the total sample (N = 1,285) the prevalence of sedentary behavior (>8 hours/day) increased by 25% during social isolation. Social isolation increased sedentary time and decreased physical activity levels in healthy individuals and in those with self-reported diagnosis of anxiety and/or depression. In both groups, the most prevalent facilitators were supervised physical activity (before the pandemic) and activities and equipment to practice at home (during the pandemic). The most prevalent barriers were the lack of time to perform physical activities (before the pandemic) and inaccessible or distance places to practice (during the pandemic). Conclusion: The COVID-19 pandemic is related to an increased sedentary behavior and reduced physical activity levels. Significant changes in perceived barriers and facilitators to exercise were observed during the social isolation period.
SAINDO DA “TORRE DE MARFIM”: A PREVENÇÃO DE VIOLÊNCIA BASEADA NA ORIENTAÇÃO SEXUAL E IDENTIDADE DE GÊNERO NA UNIVERSIDADE
Authors: PERASSOLI ENAYTON , SILVA ALEXANDRE RODRIGO NISHIWAKI DA
Published: November 2023

RESUMO: A violência contra a população LGBTQIAPN+ é um tema que atinge inúmeras pessoas que não se enquadram no padrão cisheteronormativo estabelecido socialmente. Estudos indicam que a universidade, instituição inserida na sociedade, reproduz essa forma de violência ao não criar estratégias de prevenção e superação efetivas desse fenômeno em seu interior. Amparado pela aprendizagem dialógica e pela Metodologia Comunicativa, o presente artigo apresenta os resultados de uma investigação que procurou apontar, a partir da compreensão de 18 estudantes de graduação, o modo como uma universidade pública do estado de São Paulo atua no combate ao preconceito baseado na diversidade sexual e de gênero em seus espaços, identificando os elementos excludentes e transformadores que sejam capazes de promover, prevenir e superar a violência contra pessoas LGBTQIAPN+. Como resultados principais, esta pesquisa indica que o posicionamento público da gestão dessas universidades, o estabelecimento de políticas de combate à violência, bem como a construção de espaços formativos sobre a temática para discentes, docentes e demais funcionários e funcionárias em todo o âmbito acadêmico, propiciam um ambiente mais acolhedor, respeitoso e livre de qualquer forma de preconceito contra essa população em questão.
Representations of COVID-19: the pandemic in the context of international commuting migration from mining
Authors: Mendes Lise Maria Carvalho , Silva Neto Antonio Sabino da , Barbosa Nayara Gonçalves , Cardoso Larissa de Freitas , Andrade Rosemary Ferreira de , Gomes-Sponholz Flávia Azevedo
Published: November 2023

ABSTRACT Objective: To analyze the conceptions about COVID-19 among Brazilians who carry out commuting to work in clandestine mines located on the borders between Brazil, French Guiana and Suriname. Method: This is qualitative research, from an analytical perspective, based on Social Representation Theory. Semi-structured, audio-recorded interviews were carried out with 10 Brazilians who experience work routine in clandestine mining on the border between Brazil, French Guiana and Suriname. Results: Two analytical categories emerged: “The disease of otherness”; and “Health access dimension”. Conclusion: Disease severity was attributed to another or a human body organ, and not to individuals as a whole. Access to health services was established on issues of inequity, violence and illegal practices. The nature of a transient population, which carries out commuting and informal and clandestine work, demonstrates vulnerability to COVID-19 and a lower propensity to receive care.
Condom use and drug consumption in migrants: a systematic review
Authors: Ruiz-Bugarin Cynthia Lizbeth , López-Sánchez Ulises , Aranda-Ibarra Jesus Ramon , Hernández-Vergara Carmen Ivette , Caro-Jocelyn Jimenez , Sánchez-Rojas Mario Alberto , Cruz-González Anzony Arturo
Published: November 2023

ABSTRACT Objective: To identify condom use and drug consumption in migrants, as well as the association between these variables. Method: A systematic search was carried out for articles published in Spanish and English (2017-2022), in PubMed, EBSCO, WEB of SCIENCE, Elsevier, Scielo, Redalyc, with eligible studies reporting on condom use and drug consumption, and their association. Results: The search strategy found 147 articles with the combination of terms and other sources. After excluding articles by title, abstract, and finding that they had the study variables, eight articles were included for qualitative analysis and only three met the criteria for quantitative analysis. Conclusion: Drug consumption favors inconsistent condom use, increasing the risk of acquiring an STI, and can lead to other mental health issues derived from the use of these substances.
ASSISTANCE PRACTICES OF MEDICAL AND NURSING TEAMS FOR HOSPITALIZED PEOPLE IN PALLIATIVE CARE
Authors: Moscoso Carina Rabêlo , Cordeiro Franciele Roberta , Gomes Marcela Polino , Oliveira Stefanie Griebeler , Zillmer Juliana Graciela Vestena
Published: November 2023

ABSTRACT Objective: to analyze the practices of Medical and Nursing teams for hospitalized people in Palliative Care. Method: a qualitative research study linked to the post-critical perspective, carried out between November 2020 and April 2021 in a teaching hospital from southern Brazil. The participants were three physicians, four nurses, three nursing technicians and four hospitalized adults monitored by a Palliative Care consulting team. Vignette and data extraction from medical records were used as data production techniques. The Atlas.ti program, cloud version for students, was used for data management. The data were submitted to content thematic content analysis and interpreted with theoretical notions of life technologies, therapeutic economics and biopolitics. Results: the practices were directed towards physical distress. The technologies, represented by devices and medications, were the main ways of approaching this. Even if controversial, some practices tend to be used with a view to prolonging the days of life, if that should be the family's wish. The family tends to be used as a link between the hospital and the home; however, it needs to be cared for. Conclusion: the practices of Medical and Nursing teams partially converge with Palliative Care recommendations and principles. Even under the monitoring of a specialized team, the behaviors prescribed by care teams are supported, above all, on moral values and empirical judgment. Such stance has repercussions on the resistance to accepting death as an existential event and inherent to life, keeping it still medicalized, even from different perspectives, such as Palliative Care.
PRÁTICAS ASSISTENCIAIS DE EQUIPES MÉDICAS E DE ENFERMAGEM ÀS PESSOAS EM CUIDADOS PALIATIVOS HOSPITALIZADAS
Authors: Moscoso Carina Rabêlo , Cordeiro Franciele Roberta , Gomes Marcela Polino , Oliveira Stefanie Griebeler , Zillmer Juliana Graciela Vestena
Published: November 2023

RESUMO Objetivo: analisar as práticas de equipes médicas e de enfermagem às pessoas em cuidados paliativos hospitalizadas. Método: pesquisa qualitativa, vinculada à perspectiva pós-crítica, realizada entre novembro de 2020 e abril de 2021 em um hospital de ensino do sul do Brasil. Os participantes foram três médicos, quatro enfermeiros, três técnicos de enfermagem e quatro adultos hospitalizados acompanhados por equipe de consultoria em cuidados paliativos. Como técnica de produção dos dados foram utilizadas vinheta e extração de dados de prontuários. O programa Atlas.ti, versão Cloud para estudantes, foi utilizado para o gerenciamento dos dados, submetidos à análise de conteúdo, do tipo temática, e interpretados com noções teóricas de tecnologias de vida, economia terapêutica e biopolítica. Resultados: as práticas estiveram direcionadas ao sofrimento físico. As tecnologias, representadas por equipamentos e medicamentos foram as principais formas de abordagem para tal. Algumas práticas, mesmo que controversas, tendem a ser utilizadas com vistas a prolongar os dias de vida, se esse for um desejo da família. A família tende a ser utilizada como um elo entre o hospital e o domicílio, porém, carece de ser cuidada. Conclusão: as práticas de equipes médicas e de enfermagem convergem, em parte, com recomendações e princípios dos cuidados paliativos. Mesmo sob o acompanhamento de equipe especializada, as condutas prescritas por equipes assistenciais são respaldadas, sobretudo, em valores morais e julgamento empírico. Tal postura repercute na resistência da aceitação da morte como um evento existencial, inerente à vida, mantendo-o ainda medicalizado, mesmo sob perspectivas diferenciadas, como os cuidados paliativos.
CUIDADORES FAMILIARES DE IDOSOS E CONDIÇÕES DE SAÚDE FÍSICA, PSICOLÓGICA E APOIO FAMILIAR NO CUIDADO
Authors: Sartori Ivanize Fátima Giongo , Almeida Neto Honor de , Hirdes Alice
Published: November 2023

RESUMO Objetivo: analisar a existência de sobrecarga de cuidadores familiares de idosos nas dimensões de saúde física, psicológica e apoio familiar. Método: estudo qualitativo, realizado com 23 participantes de Dianópolis, Tocantins, Brasil. Os dados foram coletados mediante entrevistas semiestruturadas em setembro de 2022. A análise dos dados foi efetuada utilizando-se a análise de conteúdo na modalidade temática de Minayo, que abrange a ordenação, a classificação e a análise final dos dados. Resultados: os resultados evidenciam que o exercício da função de cuidador está relacionado à representação social, a qual é potencializada: pelo contexto, valores culturais e familiares; pela naturalização da função da mulher como cuidadora; pela potencialização da sobrecarga em razão do excesso de responsabilidade e falta de apoio de outros membros da família; e pela presença, nos cuidadores, de sintomas psicológicos sobrepondo-se aos físicos. Conclusão: conclui-se que o apoio dos profissionais é essencial para repensar novas práticas e formas de produzir o cuidado, por meio de atividades individuais ou coletivas, com vistas a prevenir o adoecimento dos cuidadores.
TECNOLOGIAS PEDAGÓGICAS DE GOVERNO DO EU NUM CURRÍCULO CULTURALMENTE ORIENTADO
Authors: Borges Clayton Cesar de Oliveira , Neira Marcos Garcia
Published: November 2023

Resumo O presente artigo devota-se a examinar as tecnologias pedagógicas de governo do eu levadas a cabo por um currículo culturalmente orientado. Para tanto, a análise situa-se no campo teórico- -metodológico de estudos do discurso, sob a perspectiva foucaultiana, e sua relação na produção de subjetividades. A análise do material empírico, que compreendeu 138 relatos de experiências pedagógicas vinculados ao currículo cultural da educação física, propiciou inferir a ocorrência de tecnologias pedagógicas de governo do eu, que incitam à participação e à reflexão dos sujeitos da educação, de modo que, por intermédio de um enlace entre códigos de comportamento e uma moral direcionada, em alguma dimensão, à ética, engendram subjetividades democráticas e multiculturais.
A AGENDA DE PESQUISA DA SOCIOLOGIA BRASILEIRA DO INÍCIO DO MILÊNIO
Authors: Campos Luiz Augusto , Santos Marcelo Augusto de Paiva dos , Juruá Mayra , Candido Marcia Rangel
Published: November 2023

Resumo Muitos trabalhos buscaram definir a agenda de pesquisa da sociologia brasileira, sua evolução temporal e demais dinâmicas internas e externas. Porém os métodos empregados na classificação temática da disciplina ainda são rudimentares. Para contornar isso, este artigo submeteu mais de 3 mil teses de doutorado, publicadas no início do milênio, a técnicas de processamento de texto, especialmente à Modelagem de Tópicos. Os resultados indicam que nossa “nova” sociologia é marcada pela perda de importância relativa de temas tradicionais, como os estudos sobre o trabalho, em prol de tópicos mais plurais, como violência e gênero. Ao que parece, essas transformações refletem diretrizes das agências de fomento e mudanças no debate público, o que coloca novos desafios no horizonte da disciplina.
Brazilian Foreign Policy Discourses and the Quest for Ontological Security
Authors: Muñoz Luciano da Rosa
Published: November 2023

Abstract In this paper, I analyse Brazilian foreign policy with special attention to change from Americanism to Globalism in the early 1960s. This article argues that such change happened amid a crisis of ontological security. Traditional diplomats were supporters of Americanism, whereas some intellectuals and politicians came up with Neutralism, an alternative foreign policy discourse. They upheld different narratives of Brazil’s identity, whether as a Western country or a bridge between developing nations and the West. I will argue that diplomats did solve such critical situation and regain control over Brazilian foreign policy’s formulation and implementation. They did so by deactivating parts of Neutralism and carving out Globalism, which would become the new hegemonic foreign policy discourse.
Forum: Foreign Policy, Emotions and Ontological Security
Authors: Resende Erica Simone Almeida , Sandrin Paula , Solomon Ty
Published: November 2023

Abstract This forum, as a part of the special issue on New Directions for Foreign Policy Analysis (FPA), provides a diversity of answers to the question of how affects and emotions, and the search for ontological security, relate to foreign policy. By foregrounding the various ways to conceive the relationship between foreign policy, ontological security, collective identities, states’ autobiographical narratives, emotions and affective investments, the contributors to this forum examine and chart fruitful directions in FPA. Resende explores the analytical potentials of combining the theory of Ontological Security, Foreign Policy Analysis and Memory Studies to investigate how states invest in practices of ontological security by creating, remaking and defending their national narratives through historical memory. Solomon recollects how the September 11th attacks and the ensuing War on Terror contributed to his search for approaches which took affects and emotions seriously in IR, and which could help make sense of why some discourses, including foreign policy discourses, resonate with and are accepted by the audience in certain contexts. Finally, Sandrin provides an account of her encounters with the literature on the role of emotions in foreign policy and conveys how these texts helped her make sense of some puzzling aspects of Turkish foreign policy. Jimmy Casas Klausen served as lead editor of this forum. The manuscript passed through the regular double-blind peer review process to insure anonymity.
SUPERVIVENCIA A TRES AÑOS EN UNA COHORTE DE MUJERES CON CÁNCER DE MAMA DE UNA ASEGURADORA EN CALI 2017-2020
Authors: Oliveros Simón Andrés Giraldo , Gutierrez Diego Alfonso Cardona , Salazar Mauricio Rebellon
Published: November 2023

INTRODUCCIÓN: El cáncer de mama, en particular, es una preocupación significativa en la salud pública debido a su alta mortalidad. Esta investigación se centra en comprender los factores relacionados con la supervivencia a 3 años de mujeres con cáncer de mama en Cali, contribuyendo a abordar este desafío de salud. OBJETIVO: determinar los factores socio demográficos, clínicos y de atención en salud asociados a la supervivencia a 3 años de mujeres con cáncer de mama afiliadas a una aseguradora en Cali 2017-2020, generando evidencia científica para la toma de decisiones tanto en la aseguradora como en la región. METODOLOGIA: Se realizó un estudio en mujeres con cáncer de mama en Cali para identificar factores vinculados a la supervivencia a 3 años. Se analizaron datos de una cohorte de mujeres con cáncer de mama afiliadas a una aseguradora, aplicando criterios de inclusión y exclusión. Se evaluaron factores sociodemográficos, clínicos y de atención en salud. Los datos se recopilaron de fuentes secundarias y se analizaron para determinar las variables relacionadas con la supervivencia. Se cumplieron consideraciones éticas y de confidencialidad en el proceso. RESULTADOS: El hallazgo más significativo de nuestro estudio, basado en un seguimiento de tres años a 140 mujeres con cáncer de mama, es la alarmante tasa de mortalidad del 21.4%. Destacamos la importancia de diagnosticar la enfermedad en sus estadios iniciales, lo que puede marcar la diferencia en la supervivencia y el pronóstico de las pacientes. CONCLUSION: Estudio destaca la alta vulnerabilidad de la cohorte de mujeres con cáncer de mama afiliadas a la EAPB. Aunque se observó un mayor tiempo de supervivencia en ciertos grupos, la tasa de mortalidad sigue siendo significativa.
Hydration properties of composite cementitious materials containing steel slag under steam curing condition
Authors: Li Maosen , Liang Xiao , Chen Long , Liu Shuhua
Published: November 2023

Steel slag (SS) is a by-product of the steel industry, and its recycling is of great significance. In this study, the influence of SS fineness and curing regimes on the hydration properties of cement and the effects of SS content on the compressive strength of pastes were investigated. The hydration products and microstructure of pastes were further explored through X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results show that the compressive strength decreases gradually with the increase of SS, and increases with the increase of the specific surface area of SS. The compressive strength of paste after steam curing is improved, and the compressive strength of the paste mixed with 30% SS can reach more than 50 MPa after 90 days of steam curing. The hydration products of paste mixed with SS are not significantly different from those of cement, which mainly comprise calcium hydroxide (Ca(OH)2) and calcium silicate hydrate (C–S–H) gel, accompanied by a small amount of calcium carbonate (CaCO3). SS has secondary hydration after long-term ageing and can fill and refine the pore structure, according to SEM. Using SS as a supplementary material is beneficial in terms of reducing cement cost and lowering carbon dioxide (CO2) emission.
Parametric study of WEDM of titanium grade 12 using RSM and desirability approach
Authors: Pramanik Debal , Panja Bikash , Banerjee Sudip
Published: November 2023

The present experimental study aims to scrutinize the effect of different process parameters on the material removal rate (MRR) and surface roughness (SR) of titanium grade 12 alloy during wire electro-discharge machining (WEDM) using response surface methodology. Four parameters (pulse-on time, pulse-off time, wire feed and gap voltage) and three levels of each selected variable are considered to conduct the experimental work. Depending on experimental results, a mathematical model is generated for both MRR and SR. An analysis of variance (Anova) study is performed to find significant process parameters. The Anova results show that the developed models for both MRR and SR are significant, and pulse-on time is found to be the most significant parameter. Additionally, the desirability approach is used to scrutinize the single-objective and multi-objective criteria of response variables. The desirability functions for all of the cases are found to be 1. The maximum MRR is observed to be 12.4845 mm3/s, while the minimum value of SR is found to be 1.4911 μm. For multi-objective optimization, the maximum value of MRR and the minimum value of SR are obtained as 12.0942 mm3/min and 1.7167 μm, respectively. Finally, the surface morphology of the machined surfaces is examined using scanning electron microscopy micrographs.
Evaluation of the adaptive potential of plants with variegate leaf coloration
Authors:   Tsitsin Main Botanical Garden, Russian Academy of Sciences, Kabanov Alexander V. , Khokhlacheva Julia A. ,   Tsitsin Main Botanical Garden, Russian Academy of Sciences
Published: November 2023

The article presents the results of a comparative analysis of the quantitative and qualitative composition of a sample of variegated herbaceous introducents (36 names) from the collection fund of the Laboratory of Ornamental Plants, Tsitsin Main Botanical Garden, Russian Academy of Sciences. The families Poaceae, Asteraceae, Lamiaceae and Saxifragaceae have the largest number of genera containing species in which forms with this leaf color are noted. The analysis of the data of long-term field experiments allowed us to assume the presence of a multidirectional influence of adaptive characteristics on the stability in the culture of different groups of introduced plants with variegate leaf coloration. For variegate cultivars, the most widely represented in the modern collection fund of the Laboratory, differences in stability in culture were revealed depending on the ratio of the differently colored parts of the leaf blade. This group of introducers has also been studied by belonging to ecological groups, donor regions and life forms. A variant of assessing the adaptive potential of variegate introducers is proposed and tested.
Fauna and benthic communities of invertebrates of the springs and streams within the Aituar steppe (Orenburg state nature reserve)
Authors:   Perm State University, Krajneva Tatyana S. , Pan'kov Nikolay N. ,   Perm State University
Published: November 2023

The benthic (invertebrate) community of streams and springs in the Aytuar steppe includes 49 taxon. Chironomids are the most diverse (11). Mayflies (10), caddisflies (7) and stoneflies (5) are rich in species. Among other invertebrates, non-chironomid dipterans (8), mollusks (3), oligochaetes (1), amphipods (1), alder flies (1), bugs (1) and beetles (1) were recorded. The specificity of the fauna is determined by the presence of the genetically Siberian species M. borealis. Its negative feature is the absence of such wide-spread European taxa as the caddisflies of the genera Beraea, Crunoecia, and Parachiona, as well as genetically Siberian elements, the mollusks Parasphaerium rectidens (Starobogatov et Streletzkaja, 1967), stoneflies Arcynopteryx compacta (McLachlan, 1872), and Nemoura arctica Esben-Petersen, 1910, may-flies Cinygma lyriformis (McDunnough, 1924) and Ephemerella aurivillii Bengtsson, 1908, caddisflies Asynarchus lapponicus Zetterstedt, 1840 and Apatania stigmatella (Zetterstedt, 1840), common in the northern regions of the Urals and Cis-Urals. Were identified groups of invertebrates that are characteristic of both spring-fed water bodies and elements of the benthic fauna of warm-water streams. Five types of zoobenthocenoses were identified in streams. The zoobenthocenosis of cobbled (boulder-pebble) substra-tum is the most typical. Its abundance is 7.19 thousand ind./m2 with a biomass of 17.75 g/m2. The second type is the sand-gravel and pebble zoobenthocenoses (20.28 thousand ind./m2 with a biomass of 27.48 g/m2). Zoobentocenoses of boulder substratum with moss fouling, sandy substratum and silts are less widespread. Two types of zoobenthocenoses are found in springs. A community with the abundance and biomass of 6.8 thousand ind./m2 and 10.88 g/m2 respectively develops on boulder-pebble substratum, and on sandy substratum with coarse CPOM a community with a moderate level of development (number 3.80 thousand ind./m2 with a biomass of 6.44 g/m2) is observed.
Mechanisms of interaction of melatonin with lymphocytes
Authors:   Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Kuklina Elena M. , Glebezdina Natalia S. ,   Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences
Published: November 2023

Melatonin is an indoleamine synthesized from the essential amino acid tryptophan. At the system level, it is produced mainly by the pineal gland, and at the local level, by most organs and tissues, including the gastrointestinal tract, liver, kidneys, lungs, skin, tissues of the reproductive system, and many others. The hormone regulates a wide range of biological reactions in health and diseases, and has a pronounced antioxidant, anti-inflammatory and antitumor activity. Along with this, melatonin is an effective regulator of the immune system, however, the data available to date on the problem are extremely contradictory, especially for the main effectors of adaptive immunity - T-lymphocytes. On the one hand, under physiological conditions or under immunodeficiency conditions, the effects of melatonin are usually stimulatory: it enhances the proliferative response of T- and B-lymphocytes, increases the production of Th1-cytokines, and inhibits apoptosis of lymphocytes induced by various stimuli. On the other hand, there are no fewer works demonstrating the immunosuppressive activity of melatonin, in particular, suppression of the production of pro-inflammatory cytokines. The resolution of these contradictions is the goal of this review. At the same time, the work focuses on two fundamental points. First, the main part of immunostimulating effects was obtained in experiments in vitro, while immunosuppressive effects were obtained in vivo, and since melatonin controls the synthesis of a number of other hormones of the hypothalamic-pituitary-adrenal and / or gonadal axes, many of which are effective immunomodulators themselves, it direct effects in vivo can be mediated and offset by other hormones. Second, lymphocytes express three high-affinity melatonin receptors: two membrane receptors, MT1 and MT2, and a nuclear one, RORα, as well as a number of low-specific targets, all with varying affinities for melatonin. Binding of different receptors apparently triggers different signaling mechanisms. Accordingly, physiological, pathological and pharmacological concentrations of melatonin can have different immunomodulating effects, and when evaluating the effect of melatonin on the immune system, it is important to correlate the hormone concentrations with the state of the receptor apparatus of the cells under study.
Genetic diversity of Russian and European individuals Dryopteris expansa (C. Presl) Fraser-Jenkins et Jeremy (Dryopteridaceae)
Authors:   Gymnasium № 31, Malyh Sergey Yu.
Published: November 2023

The results of molecular genetic analysis (ISSR-PCR) of 112 Dryopteris expansa (C. Presl) Fraser-Jenkins et Jermy specimens collected in Russia and Europe are presented. DNA was extracted using fresh material and material from the herbarium of the South Siberian Botanical Garden (ALTB): the collection of fresh material was carried out during expeditions (40 samples from Perm Krai, Moscow, Smolensk and Tver regions), the selection of material from the herbarium was carried out by removing a part of the dried frond (72 samples from various regions of Russia and Europe). An analysis of DNA polymorphism and the genetic structure of the studied groups with the calculation of the proportion (P95) of polymorphic loci, the absolute (na) number of alleles, the effective (ne) number of alleles, the expected (HE) heterozygosity and the information-entropy measure (I) of Shannon was carried out using the POPGENE 1.31 program. To describe the genetic structure of the studied groups, the following parameters were used: the expected proportion of heterozygous genotypes (HT) in the entire group as a measure of its overall diversity; the expected proportion of heterozygous genotypes in a subgroup (HS) as a measure of its internal diversity; the proportion of intergroup genetic diversity in the total diversity or the subdivision index (GST). In addition to this, the AMOVA package was used with the calculation of the subdivision index of groups using 1000 rounds of permutations. Based on a comparison of the indicators of the Shannon information measure (I), Nei fixation index (FST), as well as intra- and intergroup variability based on the results of the analysis of molecular variants (AMOVA) obtained for D. expansa with similar indicators given for D. fragrans (L.) Schott, a conclusion is made about the inexpediency of dividing D. expansa s.l. into two independent species – D. expansa s. str. and D. assimilis S. Walker. The indicators of all indices and calculated values given in the publication can be used as a basis for comparison in other works devoted to the genetic variability of species of the genus Dryopteris in Russia.
IMPROVEMENT OF FUEL OIL VACUUM RECTIFICATION PROCESS
Authors: Gumerova Rozana Z. , Alushkina Tatyana V.
Published: November 2023

Primary oil distillation units form the basis of all oil refineries; the quality and yield of the resulting fuel components, as well as raw materials for secondary and other oil refining processes, depend on their operation. Many Atmospheric Vacuum Tubing (AVT) plants are characterized by low recovery of heavy vacuum gas oil. Insufficient selection of heavy vacuum gas oil production leads to a high yield of vacuum residue - tar, which reduces the volume of oil refining in general.The article analyzes ways to improve the process of vacuum distillation of fuel oil at CDU/AVT primary oil distillation units, and searches for ways to increase the efficiency of already built CDU/AVT plants by increasing the selection of heavy vacuum gas oil. Options for technical re-equipment are presented to improve the technical and economic efficiency of atmospheric-vacuum tubing plants with the maximum use of the best achievements in this area and the maximum possible selection of heavy vacuum gas oil at existing primary oil distillation units. The schemes of intensification during vacuum distillation by the method of fractionation of hydrocarbon raw materials by exposing it to electromagnetic oscillations, by the method of gas oil cryolysis. Besides, the schemes of fuel oil distillation according to a two-column scheme and the rectification of half-tar in an additional vacuum column are considered. The main features in the technological design of the process, as well as the features of installation operation, are noted. The proposed schemes make it possible to obtain high-quality feedstock for catalytic cracking and hydrocracking with a high recovery of vacuum gas oil.
ANALYSIS OF THE PROPERTIES OF COATINGS USED TO PROTECT THE INNER SURFACE OF PIPELINES
Authors: Rodionova Elena E. , Kozhaeva Anastasia V. , Akhmetgaliev Rustem R. , Suyashev Ildar F.
Published: November 2023

The paper considers the main properties of protective coatings applied to the inner surface of pipes and pipe products. The main factors affecting the durability of coatings during the operation of pipelines are indicated, groups of test media and test parameters for the gradation of coatings to different operating conditions are identified. The influence of various aggressive media on pipeline coatings is described, as well as test media and test parameters of protective coatings are considered. The main methods for determining the physical and mechanical characteristics of coatings are given, brief informational and descriptive references for each of them are given. Recommendations are given for testing the protective coatings of the inner surface of pipes for compliance with technical requirements, which, ultimately, will allow the selection of materials most resistant to aggressive field environments.
FIRE RESISTANCE LIMITS OF WOOD DEPENDING ON IMPREGNATION TIME
Authors: Gazizov Asgat M. , Sadykova Alina M. , Sadykov Albert I.
Published: November 2023

Due to the high demand for wood as a building material, there are many ways to improve its strength, physical and other characteristics. One of the most important factors in the sphere of fire and industrial safety of facilities in which wood materials are used is the study of increasing the fire resistance of this material. The most effective ways to improve the fire protection of wood are surface treatment with fire-retardant paints and enamels, as well as impregnation of the inner layers of wood with special compounds. The purpose of the work is to study the impregnation of wood with Pirotex, to analyze the effect of the immersion time of wood in a fire retardant composition on burning behavior and afterglow time. In the course of the studies, the average values of the first flash, afterglow duration and the combustion initiation, depending on the time of impregnation, expressed in seconds, were established. Based on these data, it is possible to interpret the conclusion about the need for wood impregnation for a certain amount of time. The result of the experiments carried out is the establishment of the most effective range of wood impregnation time. Based on the results obtained, it was found that the most qualitative result is obtained by impregnation from 8 to 24 h at a temperature of 26 ± 1 °С.
ROLE OF DECISION SUPPORT SYSTEM IN ENSURING FIRE AND INDUSTRIAL SAFETY OF OIL AND GAS PRODUCTION TECHNOLOGICAL PROCESSES
Authors: Palladina Yana A. , Ryabishina Liliya A. , Iksanov Ilnur Kh. , Andriyanov Sergey Ye.
Published: November 2023

Ensuring fire and industrial safety in the oil and gas industry is a necessary and at the same time a complex process, since it includes many factors of different directions, depending not only on the flow of the technological process, the operation of equipment, which cannot be foreseen without additional diagnostic and control systems, as well as on parameters and indicators laid down at the design stage of the facility. That is why ensuring fire and industrial safety of oil and gas production processes requires new approaches and solutions.Aim of research: implementation of a decision support system to ensure fire and industrial safety of oil and gas production technological processes.Research methods: detection and identification of defects with their subsequent integration into systems for remote monitoring and diagnostics of technical condition.Compliance with the requirements of regulatory and technical standards in the field of fire and industrial safety, along with the implementation of a decision support system based on algorithms for defects identifying, with their subsequent integration into systems for remote monitoring and diagnostics of technical state in real time will help to ensure fire and industrial safety security and take it to a new level.
Isolation of intestinal organoids from matrigel for protein or RNA extraction v1
Authors: not provided rachel.bates
Published: November 2023

Isolation of intestinal organoids from matrigel or cultrex growth domes ready for protein or RNA isolation.
Dung Spherulite Analysis and pH Testing v1
Authors: not provided bubest
Published: November 2023

The dung spherulite and pH testing methods used for sediment samples from Yavne, Israel, based upon the methods from Smith et al. 2019.
Fecal sample pooling for SARS-CoV-2 real-time RT-PCR screening v1
Authors: Wang Leyi , Leonardi-Cattolica Antonio , Kayastha Sandipty , Miller Megan
Published: November 2023

This document includes the information and procedures to do sample pooling for fecal samples and real-time RT-PCR for SARS- CoV-2 using CDC based primers and probes. Validation data for 5 sample pools (in-house and by an independent laboratory via collaborative study such as Blinded Method Test) are available upon request.
THE AUTHOR'S RIGHT TO REMUNERATION FOR THE CONTRACTUAL DISPOSAL OF ECONOMIC RIGHTS: PROSPECTS OF DEVELOPMENT IN VIEW OF THE EU ACQUIS
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Maidanyk Liubov
Published: November 2023

The purpose of this study is to highlight the current problems of the author's right to remuneration for contractual use of a work. One of the tasks of the study is to develop practical recommendations for ensuring the author's right to remuneration for contractual use through the prism of justice, taking into account the EU acquis. The work is based on the methods of synthesis and analysis, comparative legal method and formal logical method. The author's concept of fair remuneration of the author is proposed, which should be understood as a set of means for exercising the right to remuneration for contractual and non-contractual use of the work on favorable terms for the author. Fair remuneration shall be applied to the right of remuneration of the author for non-contractual use within the exceptions and limitations of economic rights, as well as for the contractual disposal of economic rights to a work, in which the author is the primal subject. The means of realization of fair remuneration include the form of author's remuneration and the terms of contracts that strengthen the position of the author. In the copyright law of Ukraine, the concept of fairness of author's remuneration as a general concept has a narrow meaning. The concept of fair remuneration in the copyright law of Ukraine applies exclusively to the non-contractual lawful use of works within the exceptions and limitations of economic rights, for which the payment of remuneration is provided on the basis of a direct indication of the law. It is proposed to extend the concept of fair remuneration not only to the non-contractual lawful use of works, but also to the contractual use of works, taking into account the proportionality of the author's participation in the income from the use of his works. Relevant amendments to the Law of Ukraine "On Copyright and Related Rights" are proposed to provide information on the amount of remuneration received, amendments to the contract in terms of the amount of remuneration in case of its disproportionately low size. It is proposed to determine the author's remuneration in contracts for the transfer of economic rights and license agreements primarily in the form of royalty, which is a percentage of the income from the use of the work
Phytochemical Screening and Profiling of Secondary Metabolites of Annona Muricata Bark
Authors: S Sudhashini , P Amudha , R Vidya , V Rani , S Satheesh Kumar
Published: November 2023

Screening of phytochemicals is a precious stair in the detection of bioactive principles present in medicinal plants and may lead to novel drug discovery). In present study aimed to investigate the preliminary phytochemical screening, fluorescence, and spectroscopic characterization in Annona muricata bark. The qualitative analysis of aqueous, hexane, ethanol, hydro-ethanolic and methanol extracts of Annona muricata bark were investigated. Among the various extracts, the hydro-ethanolic extract of Annona muricata bark contains a higher concentration of phytochemicals than other extracts and is used for subsequent studies. Quantitative analysis revealed that the Annona muricata bark has contain significant amount of phenol, flavonoids, saponin, tannin and alkaloids were present. Histochemical analysis further confirmed the presence of phytochemicals in Annona muricata bark. UV-VIS spectral analysis we can confirm that the presence of tannins and flavonoids. FTIR analysis had confirmed the presence of alcohol, phenol, aromatic, carboxylic acid, and aliphatic amines.  Results of the study concluded that rich source of phytochemicals in Annona muricata bark is responsible for their therapeutic effects. So, it is recommended as a plant of phytopharmaceutical importance and further studies are needed with these plants to evaluate their pharmacological potentials of the bioactive compounds responsible for their bio-activities and other medicinal values.
Evaluation of Anti-Diabetic Activity of Isolated Fractions of Allium Sativum
Authors: P. Pandian  , A.Madhukar  , Sampath Kumar.Ch
Published: November 2023

The present study focuses the determination of the anti-diabetic activity of the extracted fractions of Allium sativum in rats with diabetes induced through STZ. The 20 mg/kg and 40 mg/kg doses of Allium sativum were given to the rats for 28 days. Using the accu-chek active test meter, blood glucose levels were measured to assess the anti-diabetic effects of the isolated fractions. Additionally, a comparison was made with the standard anti-diabetic medication, Pioglitazone, was given to another group of rats at a normal dose of 2.7 mg/kg. The results revealed that Allium sativum had significant anti-diabetic activity. Also, the Allium sativum remained safe till 300 mg/kg in acute toxic and 1000 mg/kg in sub-acute toxic studies and had photochemically. From these findings it can be inferred that Allium sativum has lowered FBG in experimentally induced diabetic rats.
The Efficiency of Urban Transport Policies in Latin-American Cities
Authors: Basso Sotz Leonardo Javier , Silva Montalva Hugo E.
Published: November 2023

Urban sustainability requires reducing the environmental footprint of urban mobility. To achieve this goal public transport becomes key due to its lower impact on congestion, pollution, accidents and greenhouse gas emissions as compared to private transport. Thus, encouraging public transport use is a frequent goal among city authorities. For this, they often devote an important fraction of their budget to improve the quality of its service. Many cities subsidize not just the infrastructure for public transport, but also its operation based on (some of) the following reasons. 1. As a second-best policy since charging additional fees to automobile drivers to correct negative externalities may be impractical (if the externality is trip specific) or politically unfeasible. 2. Due to the Mohring effect in which the optimal frequency and network density of services grow with the demand. Thus, the waiting and access time drop for every user in the system when the demand grows, implying that the marginal social cost is lower than the average social cost (Mohring, 1972). 3. Following distributional concerns, since often lower income people use public transport more intensively.
Algunos dilemas éticos presentes y futuros ante los avances en fecundación in vitro
Authors: Reguera Cabezas Marta
Published: November 2023

El creciente campo de la reproducción humana asistida ha alcanzado hitos inimaginables. Su continuo desarrollo y las innovaciones que genera, en ocasiones, plantean dilemas tanto éticos como jurídicos. El presente ensayo trata de exponer los cambios progresivos que se están viviendo en el ámbito del origen de la vida debido al desarrollo de nuevas opciones y estrategias en reproducción humana asistida. En primer lugar, se realiza una reflexión interdisciplinar desde la ciencia, la ética y el derecho, sobre la naturaleza humana y los cambios a los que la sociedad se enfrenta, en particular, desde la perspectiva española. En segundo lugar, recoge una breve aproximación en torno a las técnicas biomédicas presentes o futuras en el campo de la reproducción humana. Concluye sobre la necesidad de reflexionar ante el vertiginoso avance de la ciencia en materia de reproducción humana asistida.
Theranostics of uterine leiomyoma: present and future
Authors: Салех О.С. , Zhelezov D.M. , Hladchuk I.Z. , Volyanska A.G.
Published: November 2023

Research objectives: to develop an algorithm for predicting the growth of uterine fibrodis, taking into account the state of epigenetic regulation.Materials and methods. The study was conducted on the basis of clinical divisions of the Department of Obstetrics and Gynecology in 2018–2021. 28 patients with uterine fibroids were examined. Expression of miRNA-29b and miRNA-146a in tumor tissue was determined in all women using real-time PCR. Obtained data were analyzed using the statistical program Statistica 10.0 (StatSoft Inc., USA).Results. The average age of the patients was 39.3 ± 1.0 years. The average number of nodes was 2.7 ± 0.4. The expression levels of microRNA-29b were most frequently determined in the range of 2–7 units and microRNA-146a in the range of 30–67 units in most of the examined tissue samples. The expression of miRNA-29b has the greatest significance for the growth forecast (Wald statistic). According to the logistic regression equation the prognostic factors are patient’s age, estradiol and progesterone level in the I and II phases of the menstrual cycle, diameter of the largest node, expression of miRNA-29b and miRNA-146a.Conclusions. This study shows that the use of miRNA expression profile as an additional marker in the diagnosis and treatment of uterine fibroids is promising and requires more detailed research. Further study of the correlation of clinical and paraclinical parameters can make it possible to predict the course of uterine fibroids, and therefore to apply an effective personalized treatment plan. Theranostics is a new approach to the diagnosis and treatment of patients, based on the uniqueness of each person in order to choose the optimal treatment strategy against the background of the molecular genetic technologies, in particular to determine epigenetic changes in hyperproliferative diseases. The study of miRNA expression may find its place in the theranostics of uterine fibroids in the future.