bluuebunny/crossref_metadata_2025 huggingface dataset:
A Plant-Produced in vivo deglycosylated full-length Pfs48/45 as a Transmission-Blocking Vaccine Candidate against malaria
Authors: Mamedov Tarlan , Cicek Kader , Miura Kazutoyo , Gulec Burcu , Akinci Ersin , Mammadova Gunay , Hasanova Gulnara
Published: July 2019

Pfs48/45 is a leading antigen candidate for a transmission blocking (TB) vaccine. However, efforts to produce affordable, safe and correctly folded full-length Pfs48/45 using different protein expression systems have not produced an antigen with satisfactory TB activity. Pfs48/45 has 16 cysteines involved in disulfide bond formation, and the correct formation is critical for proper folding and induction of TB antibodies. Moreover, Pfs48⁄45 is not a glycoprotein in the native hosts, but contains potential glycosylation sites, which are aberrantly glycosylated during expression in eukaryotic systems. Here, we demonstrate for the first time that full length, Endo H in vivo enzymatic deglycosylated Pfs48/45 antigen is produced at a high level in plants and is structurally stable at elevated temperatures. Sera from mice immunized with this antigen showed strong inhibition in SMFA. Thus, Endo H in vivo enzymatic deglycosylated Pfs48/45 is a promising candidate for the development of an affordable TB vaccine, which may have the potential to save millions.
Walking-related locomotion is facilitated by the perception of distant targets in the extrapersonal space
Authors: Di Marco Sara , Tosoni Annalisa , Altomare Emanuele Cosimo , Ferretti Gabriele , Perrucci Mauro Gianni , Committeri Giorgia
Published: July 2019

The Gibsonian notion of affordance has been massively employed in cognitive sciences to characterize the tight interdependence between hand-related actions, manipulable objects and peripersonal space. A behavioural facilitation effect, indeed, is observed for grasping actions directed to objects located in the ‘reachable’ peripersonal space. Relevantly, this relationship is supported by dedicated neural systems in the brain. The original notion of affordance, however, was directly inspired by real-time interactions between animals and their extended natural environment. Consistently, also the extrapersonal space representation can be significantly modulated by action-related factors, and the brain contains dedicated systems for the representation of topographical space and navigation. Here we examined whether a facilitation effect could be also described for a walking-related action in the far extrapersonal space. To this aim, we employed a go/no-go paradigm requiring subjects to execute a footstep ahead in response to pictures of a virtual reality environment containing objects located at different distances (near, far) and eccentricities (central, peripheral). A walking-related, facilitation effect for distant extrapersonal locations was found, suggesting an automatic trigger of walking by positions that preferentially guide spatial exploration. Based on the parallelism with the literature on micro-affordances, we propose that this effect can be described in terms of “macro-affordances”.
Separation and recovery of carbon powder in anodes from spent lithium-ion batteries to synthesize graphene
Authors: Yang Li , Yang Liu , Xu Guangri , Feng Qigao , Li Yuanchao , Zhao Erqing , Ma Jingjing , Fan Shumin , Li Xiaobo
Published: July 2019

Based on the structural characteristics of the anodes of lithium-ion batteries, an improved Hummers’ method is proposed to recycle the anode materials of spent lithium-ion batteries into graphene. In order to effectively separate the active material from the copper foil, water was selected as an ultrasonic solvent in this experiment. In order to further verify whether lithium ions exist in the active material, carbon powder, it was digested by microwave digestion. ICP-AES was then used to analyse the solution. It was found that lithium ions were almost non-existent in the carbon powder. In order to further increase the added value of the active material, graphene oxide was obtained by an improved Hummers’ method using the carbon powder. The graphene material was also reduced by adding vitamin C as a reducing agent through a chemical reduction method using graphene oxide. Meanwhile, the negative graphite, graphite oxide and graphene samples were characterized by XRD, SEM, FTIR and TEM. The conductivity of the negative graphite, graphite oxide and graphene was tested. The results show that graphene prepared by a redox method has a better layered structure, less impurities and oxygen groups in its molecular structure, wider interlayer spacing and smaller resistivity.
Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death
Authors: Shibusawa Ryo , Yamada Eijiro , Okada Shuichi , Nakajima Yasuyo , Bastie Claire C. , Maeshima Akito , Kaira Kyoichi , Yamada Masanobu
Published: July 2019

The new type 2 diabetes drug, dapagliflozin, reduces blood glucose levels and body weight by inhibiting sodium glucose transporter 2 (SGLT2) in proximal tubular cells. SGLT2 inhibitors might modulate glucose influx into renal tubular cells, thereby regulating the metabolic conditions that cause endoplasmic reticulum (ER) stress in the cells. In this study, we examined the effect of dapagliflozin on ER stress in the HK-2 proximal tubular cell line and in the kidney of db/db mice to characterise its function in diabetic nephropathy (DN). We found that dapagliflozin regulated ER stress-mediated apoptosis in vitro and in vivo. Only the elf2α-ATF4-CHOP pathway was regulated under these conditions. Notably, the drug rescued C2 ceramide-induced ER stress-mediated apoptosis and ER stress-mediated apoptosis, which might occur in DN, in db/db mice. Our study shows a novel role for dapagliflozin as an inhibitor of ER stress and suggests that dapagliflozin might be useful for the prevention of DN.
Carrier transport manipulation for efficiency enhancement in blue phosphorescent organic light-emitting devices with a 4,4′-bis(N-carbazolyl)-2,2′-biphenyl host
Authors: Yu Ziwei , Feng Haiwei , Zhang Jiaxin , Liu Shihao , Zhao Yi , Zhang Letian , Xie Wenfa
Published: July 2019

The EQE of CBP-based blue PhOLEDs is effectively enhanced by achieving a more balanced distribution of carriers in the EML.
In vitro anticancer activity of AIEgens
Authors: Yin Feng , Gu Bobo , Li Jingxu , Panwar Nishtha , Liu Yong , Li Zigang , Yong Ken-Tye , Tang Ben Zhong
Published: July 2019

AIEgens possess superior cytotoxicity, tumor invasion, and hemolysis against cancer cells and cancer stem cells. Simple structural modifications enable them as highly biocompatible, image-guided chemotherapy agents.
Systematic ligand variation to modulate the electrochemical properties of iron and manganese complexes
Authors: Rohner Stefan S. , Kinzel Niklas W. , Werlé Christophe , Leitner Walter
Published: July 2019

Systematic series of iron(+iii) and manganese(+ii) complexes are investigated by cyclic voltammetry to elucidate how the electronic properties of the ligands influence overpotential and catalytic current in the context of water oxidation catalysis.
Luminescence properties of Yb3+-doped SrTiO3: the significance of the oxygen–titanium charge transfer state on photon downshifting
Authors: López-Pacheco Germán , López-Juárez Rigoberto , Villafuerte-Castrejón María Elena , Falcony Ciro , Barrera-Calva Enrique , González Federico
Published: July 2019

Photon downshifting in SrTiO3:Yb3+ to wavelengths where a PV cell has its higher spectral responsivity is achieved upon UV excitation through an energy transfer process from a ligand-to-metal-charge transfer O2− → Ti4+ state to the Yb3+ excited state.
Flux synthesis of Ba2Li2/3Ti16/3O13 and its photocatalytic performance
Authors: Garay-Rodríguez Luis F. , Yoshida Hisao , Torres-Martínez Leticia M.
Published: July 2019

Ba2Li2/3Ti16/3O13 was synthesized for the first time by the flux method and evaluated for photocatalytic CO2 reduction.
A manganese(ii) phthalocyanine under water-oxidation reaction: new findings
Authors: Mousazade Younes , Najafpour Mohammad Mahdi , Bagheri Robabeh , Jagličić Zvonko , Singh Jitendra Pal , Chae Keun Hwa , Song Zhenlun , Rodionova Margarita V. , Voloshin Roman A. , Shen Jian-Ren , Ramakrishna Seeram , Allakhverdiev Suleyman I.
Published: July 2019

The decomposition reaction for a manganese complex under water oxidation was investigated.
Correction: Increasing steric demand through flexible bulk – primary phosphanes with 2,6-bis(benzhydryl)phenyl backbones
Authors: Bresien Jonas , Goicoechea Jose M. , Hinz Alexander , Scharnhölz Moritz T. , Schulz Axel , Suhrbier Tim , Villinger Alexander
Published: July 2019

Correction for ‘Increasing steric demand through flexible bulk – primary phosphanes with 2,6-bis(benzhydryl)phenyl backbones’ by Jonas Bresien et al., Dalton Trans., 2019, 48, 3786–3794.
Saccharomyces cerevisiaeandHanseniaspora osmophila strains asyeast active cultures for potential probiotic applications
Authors: Fernández-Pacheco Pilar , Cueva Carolina , Arévalo-Villena María , Moreno-Arribas M. Victoria , Briones Pérez Ana
Published: July 2019

This work allowed the evaluation of the gastrointestinal resistance of five yeasts (Saccharomycesand non-Saccharomyces) in order to assess some biotechnological characteristics linked to the potential probiotics.
Effect of interlayer spacing in layered perovskites on resistive switching memory
Authors: Kim So-Yeon , Yang June-Mo , Choi Eun-Suk , Park Nam-Gyu
Published: July 2019

We report here the effect of interlayer spacing in 2-dimensional (2D) perovskites of [C6H5(CH2)nNH3]2PbI4 (anilinium (An) for n = 0, benzylammonium (BzA) for n = 1 and phenylethylammonium (PEA) for n = 2) on resistive switching properties.
Ti3C2 MXene as a new nanofiller for robust and conductive elastomer composites
Authors: Li Qunyang , Zhong Bangchao , Zhang Wenqiang , Jia Zhixin , Jia Demin , Qin Si , Wang Jing , Razal Joselito M. , Wang Xungai
Published: July 2019

Ti3C2 MXene with a layered 2D structure was applied as a novel functional filler in rubber for the first time.
On–Off switching of the phosphorescence signal in a carbon dot/polyvinyl alcohol composite for multiple data encryption
Authors: Bao Xin , Ushakova Elena V. , Liu Enshan , Zhou Zhengjie , Li Di , Zhou Ding , Qu Songnan , Rogach Andrey L.
Published: July 2019

On/off switching of the phosphorescence signal is realized in a composite carbon dot/polyvinyl alcohol material via thermal annealing, water spraying, and 1532 nm laser writing, respectively, which provides a new route to multiple data encryption.
Mid-IR evanescent-field fiber sensor with enhanced sensitivity for volatile organic compounds
Authors: Alimagham Farah , Platkov Max , Prestage Joshua , Basov Svetlana , Izakson Gregory , Katzir Abraham , Elliott Stephen R. , Hutter Tanya
Published: July 2019

Increased sensitivity of mid-IR evanescent field sensing for gas-phase volatile organic compound detection using a nano-porous coating of an optical-fibre.
Low-valent homobimetallic Rh complexes: influence of ligands on the structure and the intramolecular reactivity of Rh–H intermediates
Authors: Jurt Pascal , Salnikov Oleg G. , Gianetti Thomas L. , Chukanov Nikita V. , Baker Matthew G. , Le Corre Grégoire , Borger Jaap E. , Verel Rene , Gauthier Sébastien , Fuhr Olaf , Kovtunov Kirill V. , Fedorov Alexey , Fenske Dieter , Koptyug Igor V. , Grützmacher Hansjörg
Published: July 2019

Supporting two metal binding sites by a tailored polydentate trop-based (trop = 5H-dibenzo[a,d]cyclohepten-5-yl) ligand yields highly unsymmetric homobimetallic rhodium(i) complexes. These were studied as models for Rh/C hydrogenation catalysts.
Poly(vinyl benzyl methylpyrrolidinium) hydroxide derived anion exchange membranes for water electrolysis
Authors: Li Huanhuan , Kraglund Mikkel Rykær , Reumert Alexander Kappel , Ren Xiaorui , Aili David , Yang Jingshuai
Published: July 2019

Novel anion exchange membranes with superior alkaline stability are proposed for an alkaline water electrolysis cell.
A universal synthesis strategy to make metal nitride electrocatalysts for hydrogen evolution reaction
Authors: Yu Luo , Song Shaowei , McElhenny Brian , Ding Fazhu , Luo Dan , Yu Ying , Chen Shuo , Ren Zhifeng
Published: July 2019

A universal and facile strategy has been developed to synthesize various porous metal nitrides for the hydrogen evolution reaction.
Realization of an excellent two-dimensional Heisenberg ferromagnetic system: the synthesis, structure, and thermodynamic properties of piperazinediium tetrabromocuprate
Authors: Pan Bingying , Qiu Jiaxi , Pan Binglin , Gong Xiangnan , Li Shiyan , Xu Yuliang , Kong Xiangmu , Ding Mingcui , Zhang Lichun , Feng Hu
Published: July 2019

A 2D Heisenberg ferromagnet with ultra-small interlayer coupling realized in a metal–organic crystal.
Biaxial strain induced band transition and valley–spin coupling in the ferromagnetic semiconducting WSe2/1T-FeCl2 heterostructure
Authors: Mao Xiujuan , Li Jia , Li Congcong , Liu Ze , Teng Sukai , Xu Xiuting , Liu Yang , Yin Fuxing
Published: July 2019

The structural and electronic properties of the WSe2/1T-FeCl2 heterostructure have been investigated by density functional theory and Berry curvature calculations.
An ionic polymer–metal nanocomposite sensor using the direct attachment of an acidic ionic liquid in a polymer blend
Authors: Panwar Varij , Gopinathan Anoop
Published: July 2019

An ionic polymer metal nanocomposite sensor using honeycomb P(VDF-TrFE-CTFE)/PVP/ionic liquid shows an enhanced sensing voltage compared to polyelectrolyte based P(VDF-TrFE-CTFE) sensors.
The water line emission and ortho-to-para ratio in the Orion Bar photon-dominated region
Authors: Putaud T. , Michaut X. , Le Petit F. , Roueff E. , Lis D. C.
Published: July 2019

Context. The ortho-to-para ratio (OPR) of water in the interstellar medium (ISM) is often assumed to be related to the formation temperature of water molecules, making it a potentially interesting tracer of the thermal history of interstellar gas.

Aims. A very low OPR of 0.1–0.5 was previously reported in the Orion Bar photon-dominated region (PDR), based on observations of two optically thin H218O lines which were analyzed by using a single-slab large velocity gradient (LVG) model. The corresponding spin temperature does not coincide with the kinetic temperature of the molecular gas in this UV-illuminated region. This was interpreted as an indication of water molecules being formed on cold icy grains which were subsequently released by UV photodesorption.

Methods. A more complete set of water observations in the Orion Bar, including seven H216O lines and one H218O line, carried out using Herschel/HIFI instrument, was reanalyzed using the Meudon PDR code to derive gas-phase water abundance and the OPR. The model takes into account the steep density and temperature gradients present in the region.

Results. The model line intensities are in good agreement with the observations assuming that water molecules formed with an OPR corresponding to thermal equilibrium conditions at the local kinetic temperature of the gas and when solely considering gas-phase chemistry and water gas-grain exchanges through adsorption and desorption. Gas-phase water is predicted to arise from a region deep into the cloud, corresponding to a visual extinction of AV ~ 9, with a H216O fractional abundance of ~2 × 10−7 and column density of (1.4 ± 0.8) × 1015 cm−2 for a total cloud depth of AV = 15. A line-of-sight average OPR of 2.8 ± 0.2 is derived.

Conclusions. The observational data are consistent with a nuclear spin isomer repartition corresponding to the thermal equilibrium at a temperature of 36 ± 2 K, much higher than the spin temperature previously reported for this region and close to the gas kinetic temperature in the water-emitting gas.
Pancreatic stenting to prevent post-ERCP pancreatitis: a randomized multicenter trial
Authors: Phillip Veit , Pukitis Aldis , Epstein Alexey , Hapfelmeier Alexander , Haf David , Schwab Miriam , Demir Ihsan Ekin , Rosendahl Jonas , Hoffmeister Albrecht , Schmid Roland M. , Weber Andreas , Algül Hana
Published: July 2019

Background and study aims Acute pancreatitis (AP) is one of the most common gastrointestinal disorders leading to hospitalization and the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP). Besides pharmaco-prophylaxis, pancreatic stenting has been demonstrated to protect from post-ERCP pancreatitis (PEP). However, it remains unclear which patients benefit from pancreatic stenting. We therefore hypothesized that in an unselected population, inadvertent cannulation of the pancreatic duct during first-time ERCP increases risk of PEP and that this risk can be significantly reduced by pancreatic stenting.

Patients and methods This study was a multicenter, prospective, randomized controlled trial conducted at four European centers. A total of 167 patients undergoing first-time ERCP were enrolled in this trial. In the case of inadvertent cannulation of the pancreatic duct, patients were randomly assigned to receive either a 5 French plastic pancreatic stent of various length or no routine prophylactic intervention for PEP.

Results A total of 167 patients were included in the final analysis. Prophylactic stent insertion significantly reduced the rate of PEP during first-time ERCP (odds ratio 0.43; 95% confidence interval 0.19 – 0.98; P = 0.04). The number needed to treat to prevent one case of PEP by prophylactic stent insertion after inadvertent cannulation of the pancreatic duct was 8.1 for the intention-to-treat population.

Conclusion In an unselected patient population, inadvertent cannulation of the pancreatic duct during first-time ERCP is associated with a high risk for PEP. This risk can be significantly reduced by prophylactic pancreatic stenting, which is a safe and feasible procedure.
Unterstützung pflegender Angehöriger in der allgemeinen ambulanten Palliativversorgung Vorarlberg, Austria aus Sicht der Pflege
Authors: Rizza Katharina , Mathis Gebhard
Published: July 2019

Einleitung und Hintergrund Die meisten Menschen möchten zu Hause sterben. Ein Großteil der Pflege im ambulanten Bereich wird von pflegenden An- und Zugehörigen geleistet. Deren Belastung und Überforderung resultieren oft in Krisensituationen und Hospitalisierungen der Patienten.

Ziel der Untersuchung ist der Stand der ambulanten allgemeinen Palliativversorgung in Vorarlberg, Österreich, im Besonderen, Belastungen und Bedürfnisse pflegender An- und Zugehöriger aus Sicht der Pflege.

Methode Mittels Online-Surveys wurden alle 50 ambulanten, flächendeckenden Pflegedienste Vorarlbergs eingeladen die ambulante Palliativversorgung sowie die Belastungen und Bedürfnisse pflegender Angehöriger einzuschätzen.

Ergebnisse Die Rücklaufquote beläuft sich auf 76 %. Von allen Pflegekräften haben 26 % eine Palliativweiterbildung. Die Pflegedienste (in Vorarlberg: Krankenpflegevereine KPV) geben insgesamt eine hohe Belastung pflegender An- und Zugehöriger an. Eine Überforderung im Umgang mit Sterben und Tod wird am stärksten wahrgenommen (89,5 %; n = 34 KPV); fast ebenso hoch ist das Bedürfnis nach Beratung und fachlicher Sicherheit (86,8 %; n = 33); Ängste vor Krankheitsverschlechterung, Traurigkeit und Niedergeschlagenheit nehmen 84,2 % (n = 34) wahr; Überforderung bei der Pflege sowie Angst vor Krisensituationen 81,6 % (n = 31). Fast alle KPVs (94,7 %; n = 36) führen (sehr) oft Beratungs- und Begleitgespräche.

Diskussion Der hohen Belastung (pflegender) An- und Zugehöriger sollte mit palliativer Kompetenz und systematisch begegnet werden. An- und Zugehörige sollten als Teil des Behandlungsteams in den Kommunikationsprozess einbezogen werden. Die interprofessionelle Zusammenarbeit sollte entsprechend den komplexen Anforderungen im ambulanten palliativen Setting mehr forciert und standardisiert werden.
Palliativer Konsiliardienst auf
Intensivstationen
Authors: Schallenburger Manuela
Published: July 2019

Palliative Care und Intensivmedizin scheinen primär grundlegend diverse Ziele in
der Patientenbetreuung zu verfolgen. Die Patienten mitsamt ihren Bedürfnissen
unterscheiden sich jedoch nicht grundsätzlich. Gewisse Patienten können durchaus
von der Unterstützung eines palliativen Konsiliardienstes profitieren. Im
Artikel wird eine mögliche Zusammenarbeit des Intensivteams mit dem palliativen
Konsiliardienst vorgestellt.
Vorbeugung gegen die Langzeitfolgen eines
Intensivaufenthalts
Authors: Fröhlich Martin R. , Haubner Sandra , Bucher Martina
Published: July 2019

Ein Intensivaufenthalt kann Spuren hinterlassen und zu physischen, psychischen
oder kognitiven Beeinträchtigungen führen. Der Fachbegriff hierfür lautet
Post-Intensive Care Syndrome (PICS). Follow-up-Angebote können zur Prävention
eines PICS beitragen. Was beinhalten diese Angebote und wie wirksam sind
sie?
Übertherapie am Lebensende
Authors: Thöns Matthias , Sitte Thomas
Published: July 2019

Muss ein Patient um jeden Preis therapiert werden, auch wenn es ihm keinen Nutzen
bringt? Sind Fallzahlen wichtiger als die angemessene Behandlung eines schwer
kranken Menschen? Der Beitrag nimmt sinn- und aussichtslose Maximaltherapien am
Lebensende unter die Lupe, die nicht nur Patienten und deren Angehörige
belasten, sondern auch das Pflegepersonal oft frustrieren.
Sexuelle Enthemmung bei Therapie mit Aripiprazol
Authors: Kozian Ralf
Published: July 2019

Das Auftreten einer Hypersexualität bzw. einer sexuellen Enthemmung bei Anwendung von verschiedenen Neuroleptika stellt eine Rarität dar. Bei Anwendung von Aripiprazol häufen sich jedoch Mitteilungen, nach denen es zu einer sexuellen Enthemmung bzw. auch anderen Impulskontrollstörungen wie dem pathologischen Spielen kommt. Verantwortlich dafür ist möglicherweise der Partialagonismus am D2-Rezeptor oder auch die Stimulation am 5-HT1A-Rezeptor und der 5-HT2A-Rezeptoren-Antagonismus.
The Role of Dietary Supplements in Depression and Anxiety – A Narrative Review
Authors: Hoffmann Knut , Emons Barbara , Brunnhuber Stefan , Karaca Sedya , Juckel Georg
Published: July 2019

Introduction Dietary supplements are very widely used in the general population and there is a growing market for them, which is against the recommendations of the German Society for Nutrition. There is some evidence that dietary supplements are useful additions in the treatment of psychiatric disorders. This review is an overview of available practical knowledge regarding the use of supplements in psychiatric treatment. In particular, the review focused on the diagnosis of depression and anxiety in terms of supplement treatment.

Methods This is a narrative review of the evidence regarding supplements for treating anxiety and depression. We searched PubMed to 2018. Two reviewers screened the citations and abstracted the data. Phytopharmaceutical attends and animal-based data were excluded.

Results There are strong indications regarding the impact of supplements on the selected psychiatric disorders, but at this time, there only a few randomized clinical studies available, so evidence for these findings is quite low. However, it must be noted that there are strong hints for a relationship between vitamin D level and depression. Furthermore, various supplements have got potentially an influence on the characteristics of depression.

Discussion This review summarizes the current knowledge about supplements when used for some psychiatric conditions, but the data does not provide compelling evidence in any direction. There are only indications that there is an influence of supplements on psychiatric diseases. In support of this, there is further need for high-quality studies in this field. Reviews on other diagnoses, such as schizophrenia and dementia, will be part of further work.
Bindungsstile bei erwachsenen Kindern psychisch erkrankter Eltern
Authors: Jungbauer Johannes , Kaufmann Kathrin , Metz Deborah , Großheinrich Nicola
Published: July 2019

In einer Online-Studie wurden 296 erwachsene Kinder psychisch erkrankter Eltern befragt. Das Anliegen der Studie war es, die Bindungsmuster der interviewten Personen zu erfassen und hiervon ausgehend mögliche Zusammenhänge zwischen berichteten Kindheitserfahrungen und den erwachsenen Bindungsrepräsentationen zu untersuchen. In dieser Studie wurde die deutsche Fassung der „Adult Attachment Scales (AAS-R)“ verwendet, um grundlegende erwachsene Bindungsdimensionen zu erheben. Erwachsene Kinder psychisch kranker Eltern zeigten im Vergleich zur Allgemeinbevölkerung niedrigere Werte in der Dimension „Nähe/Vertrauen“ und höhere Werte in der Dimension „Angst“. Einem klinisch relevanten ängstlich-vermeidenden Bindungsstil konnten 39 % der Befragten zugeordnet werden. Als signifikante Prädiktoren für den erwachsenen Bindungstyp erwiesen sich die in der Kindheit erlebte Sicherheit, Kommunikationsdefizite in der Familie sowie Stigmatisierungserfahrungen. In der abschließenden Diskussion der Untersuchungsergebnisse werden Bezüge zur Praxis hergestellt, indem Interventionsvorschläge für erwachsene Kinder psychisch kranker Eltern dargestellt werden.
Individual Coping Strategies Are Associated with Patient-Reported Satisfaction upon Completion of Rehabilitation following Sports-Related Knee Surgery
Authors: Everhart Joshua S. , Harris Kristie M. , Schiele Steven E. , Abouljoud Moneer , Eikenberry Alexander , Emery Charles F. , Flanigan David C.
Published: July 2019

We sought to determine whether individual coping strategies and optimism are associated with satisfaction after sports-related knee surgery at the time of rehabilitation completion and whether the association between coping strategies/optimism and satisfaction varies by surgical procedure or length of rehabilitation. A total of 104 recreational and competitive athletes who underwent knee surgery completed preoperative assessments for intrinsic optimism using the revised Life Orientation Test and coping strategies using the brief Coping Orientations to the Problem Experience inventory. Postoperative assessments at completion of rehabilitation (mean: 5.5-month follow-up.; maximum: 15 months) included satisfaction with surgery, return to prior level of sport, and International Knee Documentation Committee (IKDC-S) symptom scores. Eighty-one percent were satisfied after completion of rehabilitation with a 68% return to prior level of sport. Irrespective of surgical procedure or length of rehabilitation (p > 0.25, all comparisons), greater reliance on others for emotional support as a coping mechanism increased risk of dissatisfaction after surgery (per point: odds ratio [OR]: 1.75; confidence interval [CI]: 1.13–2.92; p = 0.01), whereas greater use of positive reframing as a coping mechanism was protective (per point: OR: 0.43; CI: 0.21–0.82; p = 0.009). Intrinsic optimism was not predictive of postoperative satisfaction (p = 0.71). Satisfied patients had mean 13.5 points higher IKDC-S scores at follow-up than unsatisfied patients (p = 0.001). Patients who returned to prior level of sport had significantly higher satisfaction scores than patients who had not. Irrespective of surgical procedure or length of rehabilitation, use of positive reframing and reliance on others for emotional support are positive and negative predictors, respectively, of satisfaction after sports-related knee surgery. Preoperative optimism is not predictive of postoperative satisfaction.
Exploitative competition between desert kit foxes and coyotes in the Mojave Desert
Authors: Kelly Erica C. , Cypher Brian L. , Germano David J.
Published: July 2019

Exploitative competition between two sympatric guild members can influence the composition and dynamics of an ecological community. We assessed potential exploitative competition between desert kit foxes (Vulpes macrotis arsipus) and coyotes (Canis latrans) by comparing food habits of the two species from 2009 to 2014 on a study site in the Mojave Desert in California. Desert kit foxes specialised on heteromyid rodents and invertebrates, while the most frequently occurring items consumed by coyotes were lagomorphs and rodents. Both species consumed a variety of food items throughout the study, but relative use of these items varied with year and season. Also, precipitation affected prey abundance, and this influenced prey consumption by the two species. The diets of desert kit foxes and coyotes overlapped extensively, which indicated possible exploitative competition. Desert kit foxes consistently had lower dietary diversity than coyotes, indicating that desert kit foxes are more specialist consumers while coyotes are more generalists. Dietary specialisation by kit foxes on smaller items may help reduce competition with coyotes and facilitate coexistence. Coyotes consumed anthropogenic material at much higher frequencies than desert kit foxes, and this subsidisation could increase competitive pressures on kit foxes if it results in greater coyote abundance. Desert kit foxes in California are not a protected species although formal protection has been proposed due to increasing human encroachment. Conservation strategies should include measures to maintain an abundance and diversity of natural food items and limit anthropogenic subsidisation of coyotes.
Residue and clearing time
Authors: Farneti Daniele , Fattori Bruno , Bastiani Luca
Published: July 2019

Introduction and aim:

In the consideration of swallowing, ‘time’ is a parameter of great interest. The pooling score (p-score), which considers the number of dry swallows needed to clear residue in the pharynx/larynx, can be made more complete by quantifying this parameter, attempting to give a more appropriate and functional criterion of the severity of an impaired swallow. The p-score, enhanced by the inclusion of the time needed to clear residue (timed p-score, tp-score) is put forward for use in clinical practice.

Matherial and methods:

Two experienced raters blindly evaluated 35 short video clips of 5 cc pureed, 5 cc liquid and 1/4 cracker bolus transits, recorded during the endoscopic evaluations of 16 patients with dysphagia of different aetiologies. For each patient, the time needed to complete the clearing of the boluses (maximum 5 swallows, total time – TT), was determined together with the FOIS and DOSS scales.

Results:

The average time necessary to clear residue for pureed, solid and liquid boluses was 22.5 s, 30.7 s and 16.6 s respectively. The inter-rater agreement between the 2 raters in applying the p-score was good (ICC > 0.800) for every consistency. A linear regression model documented a statistically significant correlation of the p-score total, the TT and the consistencies with the FOIS and the DOSS, respectively.

Discussion and conclusion:

The p-score total and the TT are correlated with the severity of dysphagia and the functional activities of the patients, so the pt-score can be useful in clinical practice to define the severity of dysphagia.
Risk factor for mortality of children among victims in Southern Thailand
Authors: Kesuma Z M , Rahayu L , Eso M , Rasudin  , Saputra R
Published: July 2019

Conflict can be defined as any type of controversy interactions between two or more parties which occur because of the differences in status, aim, value or perception. The consequence of the conflict in a region was the incidence of fatalities, both the injured and died. Children are the society at greater risk to be the victims because of the conflict. In Southern Thailand, conflicts occur in 4 provinces which the Muslim majority, those are Pattani, Yala, Narathiwat, and Songkhla. The aims of this research have identified the factors that influence the risk of child deaths during the conflict in Southern Thailand and determined the models by influence factors. The used method was the binary logistic regression method. This method was chosen because the response variable that used is dichotomous. The dichotomous response variable was the risk of children died or not during the conflict in Southern Thailand. The data used were the number of children under 18 years old who were victims of the conflict from 2004 until 2014 in Southern Thailand. The results showed that the influence risks of child death during conflict in Southern Thailand are gender (odds ratio = 1.99; CI 95% = 1.38 - 2.88), type of guns that used was bomb (odds ratio = 0.16; CI 95% = 0.1 - 0.26) and the others (odds ratio = 2.46; CI 95% = 1.55 - 3.9), and the place of the hardness occurred was open field (odds ratio = 2.9; CI 95% = 1.54 - 5.48). Generally, children there were in the open field and female have the greater risk of death to be victimized by bombs, rifles or any other types of guns during conflict in Southern Thailand.
Geochemistry of Sulphate spring in the Ie Jue geothermal areas at Aceh Besar district, Indonesia
Authors: Idroes R , Yusuf M , Alatas M , Subhan  , Lala A , Muhammad  , Suhendra R , Idroes G M , Marwan
Published: July 2019

Geochemical studies of geothermal manifestations in the Northern Zone of Mt. Seulawah Agam, one of which is Ie Jue manifestation, has been conducted. In this study, water geochemical analysis of cations and anions content was performed to observe the surface characteristics of manifestations, the type of water manifestation, the water balance of reservoir depth and to estimate depth temperature using geothermometer equations. Cations and anions measurements were conducted using atomic absorption spectroscopy, UV-Vis spectrophotometer and acid-base titration. The data analysis was determined using spreadsheet version 3 Powell Geoscience Ltd.3 September 2012 by Powell & Cumming. The geothermal water Ie Jue manifestation was acidic pH, water sulphate type was obtained from the geoindicator Cl-SO4-HCO3 and the immature water was based on plot Na-K-Mg ternary diagram. Its reservoir temperatures ranged from 690 °C to 761 °C in accordance with Na/K geothermometer equations based on results of Na/K Giggenbach and Fournier. The Ie Jue manifestations indicated a high-temperature geothermal system (high enthalpy) that could be characterized when the average temperature reached higher than 225 °C and suitable for power plant development.
Effect of varieties and processing practices on the physical and sensory characteristics of Gayo Arabica specialty coffee
Authors: Abubakar Y , Hasni D , Muzaifa M , Sulaiman  , Mahdi  , Widayat H P
Published: July 2019

Nowadays, sensory characteristics are considered as basic requirement for coffee quality, which determined its future commercial value. Gayo Arabica coffee is one of specialty coffees known by international buyers due to its unique taste and complex aroma. However, the sensory characteristics of gayo arabica coffee vary based on type of local varieties and the processing technique practiced. The present study aims to determine the effect of variety and processing methods towards physical and sensory properties of Gayo Arabica coffee. Four Gayo local varieties (Tim-tim, Borbor, Ateng Super and Multi-varieties) and three processing practices (full-wash, semi-wash and honey natural process) were investigated. The measured parameters were moisture contents and cupping quality based on Specialty Coffee Association of America (SCAA) procedure. The statistical analysis showed that local varieties and processing attributes has significant influenced (P≤0.01) on the certain sensory attributes. The interaction of both factors showed significant effects (P≤0.01) towards flavour, acidity and balance attributes. Ateng Super variety showed a high score of overall cupping attributes whilst among processing practices it showed no differences. In conclusion, all experiments produced specialty coffee based on SCAA cupping test. Ateng Super local varieties showed the highest score (85.36±0.14) and full-wash processing produced the highest cupping quality compared to others (84.79±0.03). The Q-grader also remarked that Gayo Arabica coffee has distinguished flavours such as chocolate, dark-chocolate, caramel, nutty and spicy in all experiments. However, several unpleasant remarks also appeared in honey natural process such as sour, slightly aged and over fermented taste.
Investigating public perceptions and its implication toward Trans Koetaradja policy considering latent motivation
Authors: Sugiarto S , Saleh S M , Anggraini R , Merfazi M
Published: July 2019

Urban bus system so-called Trans Koetaradja (TK) has been considered and piloted as a way to mitigate motorcycles and cars dependency in Banda Aceh, capital of Aceh Province. It is assumed that the effectiveness of the such proposed policy would be useful if the public acceptance of this policy has a positive response. Therefore, this study intends to investigate the attitudes of the public in responding to such proposed policy. The data were collected within line 3 and line 4 of TK that is City Center - Mata Ie and City Center - Ajun - Lhoknga. The data collection method used was Stated Preference (SP) with a total of 220 samples collected using a stratified random sampling method. The SP questionnaire contains information about socio-economic, travel behavior, and respondents’ perceptions representing their attitudes towards TK policy. People are dependent on their vehicles due to public transport challenging to use. The psychological indicators such as like driving a car & motorcycle and TK has limited accessibility have significant manifested to the latent variable of Inhibition of freedom of movement/activity. These sign representing the attitudes of the people in Banda Aceh would be dependence to their own vehicles and directly affected to the rejection to use proposed bus system of the proposed policy. Furthermore, male commuters who have low education level and income households more likely to autos dependent and more feeling inhibition of freedom of movement/activity if they use public transport.
Comparison of earthquake design parameters of low rise building structures based on SNI-1726-2002 and SNI 1726:2012 at 23 districts in Aceh Province, Indonesia
Authors: Saidi T , Hasan M , Fakhrurrazi
Published: July 2019

This paper presents a comparison of earthquake design parameters, i.e. response spectrum, modal mass contribution, base shear and natural vibration period, of low rise building structures based on-SNI-1726-2002 and - SNI 1726:2012 at 23 districts in Aceh Province, Indonesia. A four-story reinforced concrete frame structure is analyzed. The results show that the maximum spectral acceleration based on SNI 1726:2012 is higher than based on SNI-1726-2002 for 15 districts in Aceh. The modal mass participation for those two standards is almost the same. The base-shear force of SNI 1726:2012 is much higher than of SNI-1726-2002. The structural natural period of both SNI-1726-2002 and SNI 1726:2012 is in a good agreement.
The effect of rainfall interception loss by Palm-Oil tree towards flood discharge in Seunagan watershed of Nagan Raya district of Aceh Province
Authors: Yulianur BC A , Azmeri  , Khairuddin
Published: July 2019

Flood discharge comes from the surface run-off affected by factors such as evaporation, evapotranspiration, infiltration and interception. This research aims to predict the magnitude of interception demonstrated by a palm-oil tree and its effects toward flood discharge. This paper covers the calculations for rainfall interception loss by a palm-oil tree, designed areal rainfall, and designed flood discharge. During the calculations, the watershed is divided into two sub-watersheds. Rainfall data were obtained from Meulaboh, Beutong and Alue-Bilie station. Areal rainfall distribution obeys the pattern of Gumbel distribution. Areal rainfall of 100 years returns period for each sub-watershed are 230.81 mm and 197.59 mm before the inclusion of interception effects, while after interception effects are included the areal rainfalls are 152.94 mm and 189.09 mm. The calculated effective rainfall using the SCS (soil conservation service) method where the curve number (CN) before interception effects are 72.19 and 73.15 while 81.54 and 73.99 after the interception is accounted. Flood discharge is calculated using the method of unit hydrograph synthetic SCS. Calculation results show that designed flood discharge of 100 years return period before and after the effects of interception were 3,042.72 m3/s and 2,521.23 m3/s, respectively. It shows that rainfall interception loss by the palm-oil tree can reduce the flood discharge.
Single microtremor method for estimating site fundamental frequency at a site in the historical city of Byblos - Lebanon
Authors: Tumur-Uyal N , Setiawan B , Oucherif M S
Published: July 2019

A single ambient noise measurement has been found to be useful in investigating the near-surface geology in particularly for estimating site fundamental frequency. This single microtremor method is very attractive and has been successfully applied in many projects as the method is non-destructive, low cost, feasible for urban environments, fast, and deep penetration. Furthermore, this single microtremor method has been successfully applied in many projects. This paper presents the application of the single microtremor method to estimate the site fundamental frequency at a site in the historical city of Byblos, Lebanon. Pre-processing of industrial origin detection was carried out. Several durations of the measurements were investigated to obtain the most stable results. The site fundamental frequency was validated using one-dimensional site response analysis. The results are presented in this paper.
Wall finishing materials and heritage science in the adaptive reuse of Jakarta heritage buildings
Authors: Rahmadina M , Kusuma NR , Arvanda E
Published: July 2019

Given its tropical setting, moisture problems are inherent issues found in walls of heritage buildings in Indonesia that require replacement of wall finishing materials with specific properties. This is where heritage science becomes an important approach in the creation of plasters and paints that best resemble its original and/or provide better performance through innovations. Heritage science possesses great potential in improving evidence-led conservation work in Indonesia by incorporating properties of traditional materials with present technology for cultural sustainability that is gaining urgency in the midst of burgeoning population growth. However, despite its growing application for historically significant heritage buildings, the need for preliminary scientific testing is not commonly acknowledged and applied in the adaptive reuse of small-scale heritage buildings in Indonesia. Therefore, this paper studies two UNESCO-funded pilot projects in Jakarta and tracks the role of heritage science throughout their conversion, and aims to evaluate the constraints, by conducting literature studies and eight interviews with various stakeholders involved. It is found that heritage science is yet a key player in Indonesian conservation works, however, it helps uncover material properties of wall finishing materials that best tackle moisture problems in Jakarta heritage buildings.
Effect of sodium sulfate and sodium chloride in two-stage thermal upgrading of low-grade Nickel Lateritic Ore
Authors: Suharno B , Ramadini C , Shaleh R H , Shofi A , Nurjaman F
Published: July 2019

Selective reduction process and magnetic separation of nickel lateritic ore were conducted through the two-stage thermal mechanism with the addition of sodium sulfate and sodium chloride as the additives agent. The first thermal process was pre-heating at the temperature of 500°C and holding for 90 minutes. Afterward, the reduction continued at the temperature of 1150°C for the same holding time. The mineralogical composition of the reduced samples was determined by XRD. The microstructure of reduced nickel laterite ore was also examined using SEM-EDS. The optimum composition of the additive was the combination of 10% Na2SO4 + 10% NaCl, which produced a concentrate with 5.52% and 85.89% for nickel grade and nickel recovery, respectively.
Failure analysis of the fracture surface of the crankshaft of a vehicle
Authors: Putra T E , Husaini  , Ali N , Husin H , Zulfikar
Published: July 2019

The purpose of this study was to determine the cause of a fracture in the crankshaft of a 1000 cc gasoline engine. On the broken surface, it could be seen that the cracks started from the direction of the oil hole. A visual examination revealed that there were beach marks on the surface of the fracture, which is usually common in fatigue failure due to a dynamic load. From the test for the chemical composition, it was found that the material was classified as alloy steel. The Rockwell-based material hardness values were different. The highest hardness value of 102.2 HRB was on the outer shell portion of the crankshaft on the x and y axes at points 1 and 14. Finally, it was concluded that the reason for the fracture in the crankshaft was fatigue failure, the material hardness that did not match that of the standard, as well as the initial crack contained within the radius of crank pin number 1.
Mechanical characteristics of marble powder composite materials reinforced Kenaf Fiber against static load
Authors: Fitriadi N , Lindawati  , Ardiansyah I
Published: July 2019

Kenaf fibre is one of the strongest natural fibres in the world today. For that purpose, the purpose of this study is to create a new composite of Kenaf fibres combined with marble waste powder. The incorporation of marble powders and Kenaf fibres using a matrix of a polyester resin type has never been done. Thus, this study aims to create and test various composite material composites (mixture of matrix, marble powder and Kenaf fibre) which will produce different mechanical properties and obtain good tensile strength in test specimens with several composition variations. Preparation of test specimens was carried out with 4 (four) compositions of matrix mix and marble powder that is 50:50, 60:40, 70:30 and 80:20 with the weight of Kenaf fibre fixed 2 gram. The largest tensile test value is 63,407 MPa, obtained from 80:20 composition with the largest E value 3.03 GPa. The largest compression test value is 33.49, obtained from the composition of 60:40 with the largest E value of 2.35 GPa. The largest bending test value is 19.80 MPa, obtained from the composition of 80:20 with the largest E value of 36.55 GPa. From the research results of the tensile test, compression test, and bending test which possess good value is between composition ratio 60:40 and 70:30.
Effect of cutting parameter on tool wear of HSS tool in drilling of Kevlar composite panel
Authors: Iqbal M , Bahri S , Akram A
Published: July 2019

The paper reports the tool wear in the drilling of composite panel in various cutting conditions. The drilling process was applied to 4mm thickness Kevlar composite panel by using HSS drill tool (2 flutes, 12 mm diameter, 17 mm length and 118° drill point angle). The process was conducted by using a vertical machining center. The tool wear was measured by using an optical microscope with the max precision 0.01 µm. The drilling process was conducted with a constant feed rate (75 mm/min) and three levels of spindle rotation speeds (1000, 3000 and 5000 rpm). Each cutting condition was applied to two different drill tools. In order to investigate the wear rate, the tool wear was measured in several levels of cutting time (i.e., after drilling of 5, 10, 20 and 30 drill holes). The result of the experiment shows that the cutting speed gives significant effect to the tool wear of HSS drill tool when drilling Kevlar composite panel. Higher cutting speed produced higher tool wear at any cutting time level. The result of the experiment also shows the effect of continuous / discontinuous cutting. Higher tool wear was found in a direct 20 holes drilling, compare to paused drilling (i.e., start with 10 holes, pause for 20 minutes then continue with other 10 holes).