bluuebunny/crossref_metadata_2025 huggingface dataset:
PERBANDINGAN AKTIVITAS ANTI BAKTERI PRODUK PASARAN SEDIAAN TOILETRIES YANG MENGANDUNG EKSTRAK DAUN SIRIH (Piper betle L.)
Authors: Indah Nasution  , Minda Sari Lubis  , Rafita Yuniarti  , Haris Munandar Nasution
Published: May 2023

Toiletries adalah kebutuhan pembersih badan sehari-hari, yang menjadi bagian dari kebutuhan antara lain sabun dan pembersih pada gigi yang saat ini sudah menjadi kebutuhan yang wajar. Daun sirih (Piper betle L.)  banyak digunakan sebagai bahan obat alternatif untuk mengobati berbagai jenis penyakit. Bakteri dominan menyebabkan berbagai penyakit mulut, salah satunya Staphylococcus auerus. Staphylococcus aureus merupakan flora normal pada kulit serta rongga mulut yang dapat memproduksi toksin, bersifat gram positif, dan termasuk bakteri aerob. Tujuan penelitian ini adalah untuk mengetahui perbandingan aktivitas anti bakteri terhadap produk toiletries yang diuji dengan menggunakan bakteri Staphylococcus aureus. Pengujian yang dilakukan antara lain yaitu identifikasi bakteri dan uji aktivitas antibakteri. Hasil uji aktivitas produk pasaran sediaan toiletries yang mengandung ekstrak daun sirih terhadap Staphylococcus aureus dengan menggunakan kosentrasi 25% yang tertinggi setelah dilakukan orientasi tiga penggulangan pada penelitian sampel perbandingan pertama pasta gigi sampel A1 rata-rata zona hambat 24,0 mm dibandingkan pasta gigi sampel A2 rata-rata zona hambat 9,0 mm, pada perbandingan dua menggunakan produk pasaran obat kumur sampel B1 rata-rata zona hambat 9,4 mm dibandingkan dengan sampel B2 rata-rata zona hambat 19,9 mm dan perbandingan tiga sabun padat sampel C1 rata-rata zona hambat 17,7 mm dibandingkan dengan sabun sampel C2 rata-rata zona hambat 23,8 mm. Aktivitas antibakteri tidak terlalu kuat zona hambat terhadap produk toiletries berupa pasta gigi ekstrak daun sirih pada sampel A2 terbilang zona hambat yang didapat tergolong lemah, dan pada produk pasaran sediaan toiletries obat kumur ekstrak daun sirih pada sampel B1 juga dinyatakan tergolong zona hambat lemah dibandingkan.
ВИВЧЕННЯ ЕФЕКТИВНОСТІ ТА ПЕРЕНОСИМОСТІ ДІЄТИЧНОЇ ДОБАВКИ «АЛЬЦИНАРА» У ПАЦІЄНТІВ З ГІПЕРХОЛЕСТЕРИНЕМІЄЮ
Authors: Зупанець Ігор Альбертович , Безугла Наталія Петрівна , Тарасенко Ольга Олександрівна
Published: May 2023

У статті наведені результати клінічного дослідження з вивчення ефективності та переносимості ДД «Альцинара» виробництва ПАТ НВЦ «Борщагівський ХФЗ» порівняно з Плацебо у добровольців з гіперхолестеринемією. Добровольці основної (30 осіб) та контрольної груп (30 осіб) амбулаторно приймали ДД «Альцинара» протягом 90 днів по 2 таблетки 3 рази на день та Плацебо (по 2 таблетки 3 рази на день протягом 90 днів) відповідно. Оцінку ефективності ДД «Альцинара»/Плацебо проводили через 45±2 та 91±2 днів від початку прийому ДД «Альцинара»/Плацебо на підставі динаміки показників ліпідограми; переносимість оцінювали на підставі реєстрації та аналізу побічних реакцій/побічних явищ. Згідно з отриманими результатами ДД «Альцинара» сприяє поліпшенню ліпідного профілю у добровольців з гіперхолестеринемією через 3 місяці прийому, про що свідчить статистично значуща різниця між групами за основним критерієм ефективності – частка добровольців, віднесених до категорії «Застосування ефективне». Гіполіпідемічний вплив ДД «Альцинара» проявляється не тільки у зниженні рівня ліпопротеїдів низької щільності, а також і тригліцеридів. Досліджуваний продукт здатен підвищувати вміст ліпопротеїдів високої щільності, зниження яких є окремим предиктором розвитку та прогресування атеросклерозу. Небажані побічні ефекти у разі прийому досліджуваних продуктів виникли загалом у 23,7% добровольців та відзначалися у кожній групі без статистично значущих відмінностей за частотою. Найбільш часто спостерігалось виникнення диспепсії (16,13% випадків) та головного болю – 16,13% випадків. Таким чином, гіполіпідемічну дію ДД «Альцинара» можна вважати доведеною, тому її застосування як спеціального харчового продукту для тривалого використання особам з гіперхолестеринемією та/або особам зі схильністю до гіперхолестеринемії (обтяжений родинний анамнез, надлишкова маса тіла, нераціональне харчування, цукровий діабет тощо) буде зменшувати ризик розвитку атеросклерозу та його фатальних наслідків.
Is It Us or Them? The Challenge of Getting Journalists to Participate in Academic Research
Authors: Blanchett Nicole , Mellado Claudia , Brin Colette , Allah Sama Nemat , Vallender Cheryl
Published: May 2023

For journalism research rooted in a sociological framework, gaining access to journalists is crucial for data collection. However, journalists are documentably difficult to recruit as participants, frequently due to limited time and resources in shrinking newsrooms, sometimes because of roadblocks put up by leery newsroom management. As part of the data collection process for the Canadian branch of the international Journalistic Role Performance project, researchers tracked issues raised by journalists that may have impacted survey recruitment and completion. These issues were frequently grounded in the context of survey questions designed to be operationalizable in vastly different cultures, and were also documented by other researchers in both the Global North and South who were cooperating in this comparative study. Despite first refusing or completely refusing survey participation, though, some Canadian journalists were willing to be interviewed, giving researchers the opportunity to explore how to best engage journalists in the research process, and design research tools to be shared in different media systems. Using a lens of social exchange, this paper provides unique insight, from the perspective of researchers and participants, on the importance of relationship-building as a focal point in order to adequately contextualize findings within a sociology of news framework.
Pengaruh Disiplin terhadap Kinerja Karyawan pada Rumah Sakit Tk. IV DR. Bratanata Jambi
Authors: Pratama Agung Aditia
Published: May 2023

With the hope that the results of work with a desire so that it has an impact on improving work performance.  Therefore, coaching and development of employee performance is treated effectively in order to achieve a smooth process of activities in an organization that will come.  The research variable is work discipline on employee performance.  The research population is hospital employees dr.  Bratanata Jambi.  Slovin sampling method.  Samples were taken 100 people.  The research instrument used a questionnaire containing 18 items. The research method was carried out using a simple linear regression analysis tool with the help of SPSS 20. The test carried out was a hypothesis test, namely test and to find out how much the coefficient of determination (R2) was, based on the results of this study that partially  service quality has a significant effect on patient satisfaction because the count is greater than t table of 3.190 > 0.196, so it can be said that there is a positive effect.  The coefficient of determination is 9.4% while the remaining 90.6% is influenced by other variables.  This means that work discipline has a positive and significant effect on employee performance at the hospital, dr.  Bratanata Jambi.  The result of the simple linear regression analysis is Y = 23.766 + 0.317 X+e
Pengaruh Earning Per Share, Investing Cash Flow dan Economic Value Added terhadap Harga Saham pada Sub Sektor Otomotif dan Komponen yang Terdaftar di Bursa Efek Indonesia Periode 2015-2020
Authors: Mahendra Anggi
Published: May 2023

The stock price is a form of public trust in the company's performance. Stock prices are influenced by two factors, namely fundamental factors or factors related to the performance of a company and market factors (trust of investors and potential investors), factors that are determined from external to the company. The purpose of this study is to determine the effect of Earning Per Share (EPS), Investing Cash Flow (ICF), and Economic Value Added (EVA), on Stock Prices in Automotive and Component Sub-Sector Companies Listed on the Indonesia Stock Exchange for the 2015-2020 period. The population used in this study were 13 companies, and the sample was 5 companies using purposive sampling technique with the criteria set by the author. The analysis used is multiple linear regression analysis method. Based on the results of simultaneous testing, it is obtained that the variables Earning Per Share, Investing Cash Flow and Economic Value Added simultaneously have a very strong influence on the Stock Prices of Automotive and Component Sub-Sector Companies listed on the Indonesia Stock Exchange, so that the first hypothesis is proven and accepted. While the partial test results Earning Per Share has a positive and significant effect on stock prices, Based on the result of the study assisted SPSS software, the regression equation Z Score Y = 8,003E-18 + 0,838X1 – 0,131X2 – 0,057X3 + e Simulations the independent variables have a significant effect on the dependent variable which is indicated by fcount > ftabel and patially has a positive effect. R square 92,6% and rest 7,4% explain other variable outside research model
Pengaruh Fasilitas Kerja terhadap Kinerja Karyawan pada Cv. Asla Jambi
Authors: Balqis Aulia
Published: May 2023

The purpose of this study was to determine and describe the work facilities and employee performance of CV. ASLA Jambi, to determine and analyze the effect of work facilities on the performance of employees of CV. ASLA Jambi. The benefits of this research provide additional information for interested parties in the industrial world about work facilities that have to do with employee performance so that efforts can be made to maintain work facilities that can improve work for employees. The research method uses descriptive analysis methods with library research, field research, and Questionnaires. The location of this company is at Jl. Abdul Rahman Saleh No. 57 Rt.09/03 Ex. Old Red Paal Kec. South Jambi. Company CV. Anugrah Sinar Laut Abadi (ASLA). The results show that the t-count value is 4.627 calculations using the SPSS program while the t-table is 2.034 with a significant level of 5%, df (32) from the t-distribution table. Shows that the t-count value is greater than the t-table (t-count t-table ) 4.627 2.034. This shows that work facilities have an influence on employee performance at CV.ASLA Jambi. So that Ho is rejected and H1 is accepted. It is hoped that CV. ASLA Jambi will pay attention to facilities, especially machines and equipment that are not sufficient or incomplete in order to support employee work processes and have an impact on work results.
Pengaruh Gaya Kepemimpinan Terhadap Kinerja Pegawai di Museum Siginjai Kota Jambi
Authors: Hasnur Mardani
Published: May 2023

Organization and employees are two things that need each other. Improving employee performance will bring progress for the institution or organization to be able to continue to carry out the goals to be achieved. Leadership style is a process of directing, influencing, and motivating members to achieve organizational goals to help create a more productive work atmosphere at work. The leader's behavior affects the understanding, psychological condition, and performance of members. The Siginjei Museum in Jambi City is one of the is a management implementing unit which is a parliamentary institution that serves the interests of the community and its progress does not seek profit but seeks to collect, maintain, research, exhibit, and communicate material objects of humans and the environment for the purposes of study, education, and enjoyment. This study aims to describe and analyze the leadership and performance of employees at the Siginjei Museum, Jambi City. Research data obtained from respondents through questionnaires, focus groups, and panels, or also data from interviews with informants. The analytical method used is descriptive analysis, verification, and simple regression analysis. Statistical analysis was carried out using the SPSS 20 program. Based on the results of interviews and questionnaires, it shows that the leadership style and performance of employees at the Siginjei Museum in Jambi City are good. The regression model obtained is: Y= 25,265 + 0,535 X+ e. If the leadership style increases by 1 point or temporary unit, then the employee performance variable will increase by 0,535. Based on the t-test shows that leadership style has a positive and significant effect on employee performance because the significance value is 0,001 < 0,05. So it can be said based on the results of hypothesis testing that leadership style affects employee performance by 24.3% and the rest is influenced by other variables.
Pengaruh Pendidikan dan Kesehatan terhadap Produktivitas tenaga Kerja di Provinsi Jambi tahun 2002-2020
Authors: Novista Sylvia
Published: May 2023

The problem that always arises in societal life is poverty. Various efforts made by the Government to reduce poverty reduce poverty can not be done partially but should concern some aspects related to poverty.  This research aims to analyze the factors that affect poverty in Jambi city in 2003-2017. The factors analyzed are economic growth rate, unemployment, HDI and poverty in Jambi city. The data used in this research is sourced from the Central Statistic Agency (BPS) which has a record of data from 11 regencies/cities in Jambi province.  The method used in this research is a method of double linear regression using SPSS method with research time of 2003-2017. The results of this study showed that of the 3 variables tested, the economic growth rate was influential Significant impact on poverty, human Development index has no significant effect on poverty. While unemployment significantly positively affects poverty. The result of this study is LPE, IPM, UN, had a significant impact on the poverty rate of the Jambi city. It was with the amount of coefficient determination 47,30% the rest  52,7% was influenced by more variables than research.
Analisis Pengaruh Promosi dan Kualitas Produk terhadap Keputusan Pembelian Onoy Cake & Bakery di Kota Jambi
Authors: Utami Lira Permata
Published: May 2023

The purpose of research is to find out the promotion, quality of products and purchasing decisions on Onoy Cake & Bakery in Jambi city. In discussing this problem the author uses qualitative descriptive methods by looking for information about the symptoms, clearly establishing the goals to be achieved, collecting data as material to make research.Onoy Cake & Bakery was founded by Suci Andhita as the owner of the business. Onoy Cake & Bakery is an UMKM that shells bread and cake. Onoy Cake & Bakery was established since 2012 until now. And Onoy Cake & Bakery have a store branch.The population in this study was consumers of Onoy Cake & Bakery in the city of Jambi. The sample was determinated by the Judgement Sampling method with a total 0f 100 customer respondents Onoy Cake & Bakery about promotion, product quality and purchasing decisions. Hypothesis tested with T test and F test.Based on the result of multiple linear analyze, the equation Y = 1,533 + 0,163.X1 + 0,661.X2+ e. the t-test value for promotion  (X1) is 2,076 and product quality (X2) is 6,618. With the F test of 0,000. The value of R square is 0,640% or 64% while the remaining 36% is influenced by other factors.The conclusion of this study is that promotion and product quality have a significant influence either simultaneous or partially on purchasing decisions.
Pengaruh Disiplin Kerja terhadap Kinerja Pegawai Negeri Sipil pada Dinas Pendidikan Kota Jambi
Authors: Kurniawan Asmi
Published: May 2023

The purpose of this study was to determine and describe the description of work discipline and employee performance at the Jambi City Education Office, as well as to determine and analyze the effect of work discipline on employee performance at the Jambi City Education Office. The analytical method used is quantitative data analysis method, namely the analysis used to test the relationship or influence of the independent variable (X) and the dependent variable (Y). The analytical tools in this study are simple linear regression analysis, hypothesis testing and the coefficient of determination (R2). Based on the criteria, the samples taken were 32 Civil Servants at the Jambi City Education Office. From the results 1. Discipline at the Jambi City Education Office is categorized as high with a score of 121 while performance is categorized as high with a score of 119.9. 2. Discipline variable (X) has a significance value of 0.000, where the P-value is smaller than 0.05 and the t-count is 5.580 which is greater than the t-table (2.042). This means that there is a significant influence between discipline (X) on the performance of civil servants (Y) at the Jambi City Education Office.
Pengaruh Motivasi Kerja Terhadap Kinerja Pegawai Pada PT. Bintang Pinang Cemerlang Kota Jambi
Authors: May May
Published: May 2023

Work motivation plays a very important role in employee performance. Therefore, the purpose of  this research is to describe the work motivation and employee performance, and to find out and analyze the effect of work motivation on employee performance in PT. Bintang Pinang Cemerlang Kota Jambi. Research methods in this study is descriptive and quantitative method. Data analyze use SPSS Ver 22 and using models simple linier regression with result of count Y = 1,116+0,527X+e. The test of determination with R2 of 37,6%. T test by comparison tcount 3,547 > ttable 0,3338 then Ho accepted Hi be. Rejected. To analyze the effect of work motivation on employee performance on PT. Bintang Pinang Cemerlang Kota Jambi. The distribution of questionnaires with a then the sample in this study amounted to 35 people respondent. Work Motivation regression coefficient (X) is 0,527, meaning that work motivation (X) has increased by 1%, so employee performance (Y) PT. Bintang Pinang Cemerlang Kota Jambi. The coefficient of determination is known from the value of R2=0,376 (37,6%) which means that work motivation (X) is able to explain employee performance  (Y) at the PT. Bintang Pinang Cemerlang Kota Jambi that is equal to 37,6% and the remaining 62,4% is influenced by other variables. Not investigated in this study. Based on t-test, t-count value is 3,547 and the t-table is 0,3338. From the comparison results, it can be seen that  the test by comparison tcount 3,547 > ttable 0,3338 then Ho accepted Hi be. Rejected. Meaning that brand image affect purchasing decisions at PT. Bintang Pinang Cemerlang Kota Jambi.
Pengaruh Kepemimpinan Terhadap Kinerja Karyawan di PT. Mitra Bumi Gemilang Kota Jambi
Authors: Hastri Andi Amelia
Published: May 2023

The Effect of Leadership on Employee Performance at PT Bumi Gemilang Jambi City. This study aims to find out how the influence of leadership on employee performance at PT Bumi Gemilang, Jambi City. The population in this study are all employees within the scope of PT. Mitra Gemilang, City of Jambi, totaling 45 people. Data collection was carried out using documentation methods and questionnaires. The data analysis technique used is descriptive statistical analysis, and the hypothesis is tested by simple linear regression analysis. The linear regression equation formed Y = 18,353 + 0.453 X. Constant (a) = 18.353 This means that if the independent variable (leadership style) is considered equal to zero (0), then the value of the dependent variable (employee performance) is 18.353. Leadership Style (X) = +0.453 The coefficient value of the leadership style variable has a positive sign on employee performance with a regression coefficient value of 0.453. This shows that each value of the leadership style variable is increased by 1 point or a temporary unit, then the employee performance variable will increase by 0.453. It shows that leadership style has a positive and significant effect on employee performance due to a significance value of 0.000 <0.05. So that it can be said based on the results of testing the hypothesis that leadership style influences employee performance by 28.9% and the rest is influenced by other variables. It is suggested to further researchers to broaden the object of research so as to obtain more complete and broader information regarding the influence of leadership style on employee performance.
Management tendencies and needs: a joint proposal to maximize soybean grain yield
Authors: Pradebon Leonardo Cesar , Carvalho Ivan Ricardo , Sangiovo Jaqueline Piesanti , Loro Murilo Vieira , Scarton Victor Delino Barasuol , Port Eduarda Donadel , Mallmann Guilherme , Stasiak Guilherme , Maciel Dassaiévis Gonzatto , Lopes Pedro Felipe , Carioli Gabriel
Published: May 2023

The objective of the study was to evidence efficient management strategies in order to maximize soybean grain yield. The experiments took place at Centro de Pesquisas e Resultados Agronômicos das Missões (CPRAM), located in Entre - Ijuís - Rio Grande do Sul, Brasil. Three experiments were carried out in a randomized block design with four replications per treatment. The experiments were based on soybean crop management. Soil cover with vetch enhanced soybean grain yield. The cultivar BRS 5804RR® presented the best productive performance in the arrangements of 7 and 11 seeds m-1. Artificial defoliation did not influence soybean grain yield.
The development and validation literacy scale for pre-service mathematics teachers
Authors: Xiaofeng Lan  , Ying Zhou
Published: May 2023

The 21st century is an era in which education determines the future of society. The relevant theoretical research on core literacy is mainly carried out around students, and the research on the core literacy of pre-service mathematics teachers in ethnic areas has not yet begun. By consulting literature and existing mature questionnaires, combined with pre-service mathematics teachers' characteristics in ethnic areas, a "core literacy scale of pre-service mathematics teachers in ethnic areas" was compiled. Taking 412 pre-service mathematics teachers in Guangxi, China as the research object, using SPSS22.0 and AMOS24.0 to carry out project analysis, exploratory factor analysis, and confirmatory factor analysis on the data, the scale was revised accordingly, and the formal scale contains knowledge There are 3 dimensions of, ability, character, and the corresponding 9 factors. The scale compiled has good reliability and validity. It can be used as an effective tool to measure the core literacy of pre-service mathematics teachers in ethnic areas, and it also provides a basis for in-depth research on the current situation and strategies of training the core literacy of pre-service mathematics teachers in ethnic areas.
Okul Öncesi Dönem Çocuklarının Karar Verme ve Eleştirel Düşünme Becerilerinin İncelenmesi
Authors: Aydemir Özalp Tuğba , Durmuşoğlu Mine Canan
Published: May 2023

Araştırmada 5-6 yaş grubu çocukların karar verme ve eleştirel düşünme becerilerinin düzeyleri ve aralarındaki ilişkinin incelenmesi amaçlanmıştır. Ayrıca belirlenen bazı değişkenlerin karar verme ve eleştirel düşünme becerileri ile ilişkileri de değerlendirilmiştir. Çalışma, nicel araştırma yöntemlerinden ilişkisel tarama modelinde gerçekleştirilmiştir. Veri toplama aracı olarak “Demografik bilgi formu”, “Karar Verme Becerileri Değerlendirme Aracı-Çocuk Formu” ve “5-6 Yaş Çocukları İçin Eleştirel Düşünme Becerileri Testi (ÇEDT)” kullanılmıştır. Verilerin analizinde Spearman korelasyon katsayısı analizi, Mann Whitney-U Testi ile Kruskal Wallis-H Testi yapılmıştır. Sonuçta çocukların karar verme ve eleştirel düşünme beceri seviyelerinin orta düzeyde olduğu ve iki beceri puanları arasında anlamlı bir ilişki olmadığı tespit edilmiştir. Çocukların, anne öğrenim durumu, anne çalışma durumu, kardeş sayıları ve diğer kardeşlerin yaşı ile eleştirel düşünme becerisi puanları arasında anlamlı ilişkiler bulunurken, anne öğrenim durumu ve anne çalışma durumu ile karar verme becerisi puanları arasında anlamlı ilişkiler bulunmuştur. Ayrıca cinsiyet, okul öncesi eğitim alma süresi ve baba öğrenim durumu ile karar verme ve eleştirel düşünme beceri puanları arasında anlamlı bir fark olmadığı bulunmuştur.
Digital Assessment Tools for Special Education Teachers: Challenges and Opportunities
Authors: Özer Şanal Seda
Published: May 2023

This study was conducted to reveal the views of special education teachers on digital assessment tools. The researcher collected data from 38 special education teachers through focus group interviews. The opinions were coded under two main themes: challenges and opportunities. Under the main theme of challenges, there are sub-themes of knowledge and skills, curriculum, time, integration, collaboration, management and cost. Under the main theme of opportunities, there are sub-themes of virtual classroom, digital bag, new collaborations, paperless classroom, diversity of approaches, individualized exams, active learning and feedback. The themes are discussed within the scope of instructional technologies, current literature on special education and recommendations are included.
The Role of Mobile Technologies in Blended Learning Environments
Authors: Ergün Elverici Sibel
Published: May 2023

Mobile technologies exist in a wide spectrum and have a great impact on today’s world. One of the reasons of mobile technologies’ becoming a vital part of everyday life may be various features they possess such as easy access to content with no time and limit boundaries. This has brought up the question whether they may assist language learning.  Considering Web 2.0 tools in the context of mobile technologies, for this study a well-known Web 2.0 tool has been chosen to investigate its effects, Duolingo, on students’ academic performance when used in blended learning settings to support formal language education. The academic performance levels of students are determined before and after the intervention in a high school in accordance with an instructional design prepared to support students in and out of school hours.  Data were analyzed by using descriptive analyses techniques. The results of the study are discussed considering the significant difference in students’ academic performance after the intervention.  It can be concluded that there are possible advantages of integrating a Web 2.0 tool in blended learning contexts.
İlköğretim Matematik Öğretmenliği Lisans Programının Paydaş Görüşlerine Göre Değerlendirmesi
Authors: Özden Celalettin , İlgün Şükrü
Published: May 2023

Öğretmen yetiştirme programlarına yönelik 2018 yılında yenilenerek uygulamaya konulan farklı branşlara ait öğretim programları bulunmaktadır. Bu araştırmada ilköğretim matematik öğretmenliği lisans programı (İMÖLP) ele alınmıştır. Araştırmada İMÖLP öğrencilerinin ve öğretim üyelerinin mevcut uygulanmakta olan lisans programına yönelik görüşlerinin program geliştirmenin dört temel boyutu açısından analiz edilerek ortaya konulması amaçlanmıştır.  Nitel araştırma yöntemi ile yürütülen çalışmada ilköğretim matematik öğretmenliği bölümünden 28 öğretmen adayı ve 9 akademisyen araştırmanın çalışma grubunu oluşturmuştur. Nitel verilerin analizinde NVIVO 12 paket programı kullanılmıştır. Araştırmada öğretmen adaylarının ve öğretim üyelerinin görüşlerine göre lisans programındaki matematik alan ders saatlerinin ve kredilerinin artırılması yönünde isteklerin olduğu bulgulara ulaşılmıştır. Bunlara ek olarak araştırmada meslek bilgisi derslerinin yeterli düzeyde olduğu, seçmeli derslerin çeşitlendirilmesi gerektiği, derslerde uygulama imkanlarının artırılması, basamaklılık özelliği olan derslerin birbirini takip eden dönemlerde uygulanması, derslerde daha fazla öğretim materyali kullanılması ve süreç değerlendirmesine ağırlık verilmesi bulgularına ulaşılmıştır. Sonuç olarak İMÖLP’de pedagojik alan bilgisini ön plana çıkaran mesleki derslerin ağırlıkta olduğu bir program yapılanması olduğu görülmektedir.
Der Imperativ im Chaladsch
Authors: Doerfer Gerhard
Published: May 2023

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MicroRNAs as novel biomarkers for the diagnosis and treatment of pediatric diseases
Authors: Jeong Hwal Rim , Hwang Il Tae
Published: May 2023

MicroRNAs (miRNAs) are highly conserved noncoding RNAs that regulate gene expression by silencing or degrading messenger RNAs. Many of the approximately 2,500 miRNAs discovered in humans are known to regulate vital biological processes, including cell differentiation, proliferation, apoptosis, and embryonic tissue development. Aberrant miRNA expression may have pathological and malignant consequences. Therefore, miRNAs have emerged as novel diagnostic markers and potential therapeutic targets for various diseases. Children undergo various stages of growth, development, and maturation between birth and adulthood. It is important to study the role of miRNA expression in normal growth and disease development during these developmental stages. In this mini-review, we discuss the role of miRNAs as diagnostic and prognostic biomarkers in various pediatric diseases.
MEMAKNAI HUKUMAN MATI BAGI KORUPTOR BERDASARKAN FILSAFAT HUKUM
Authors: Akmal Diya Ul , Madda Syafrijal Mughni
Published: May 2023

The existence of the death penalty for corruptors in Prevailing Laws is part of efforts to eradicate corruption. Corruption is considered to have become entrenched so that extraordinary efforts are needed to deal with it. The firmness of sanctions is expected to give fear to everyone when they want to commit corruption. There are differences of opinion regarding the provision of the death penalty. To minimize these differences, a philosophical study is needed to understand them. This study uses a normative juridical method with a statutory approach. The data used is secondary data obtained through literature study. The Constitution has explicitly regulated human rights and their limitations. These restrictions are carried out when someone violates the rights of another person. Corruption is a systematic act that harms the wider community. So that the death penalty for corruptors is a form of providing justice to the community. Law enforcement officers must have the courage to apply the death penalty but must be adjusted to the provisions contained in the Legislation.
Penerapan Metode SMART untuk Menentukan Kelayakan Perpustakaan Sekolah
Authors: Sukamto - , Kurniawan Rahmad , Jukris Avisha Delinda
Published: May 2023

Perpustakaan sekolah harus diakreditasi dengan tujuan untuk meningkatkan kualitas perpustakaan. Dinas Perpustakaan dan Kearsipan Kota Pekanbaru (DISPUSIP) dalam menentukan suatu perpustakaan sekolah yang layak untuk diakreditasi masih dilakukan secara manual. Untuk itu diperlukan suatu sistem  pendukung keputusan (SPK). Penelitian ini menggunakan metode SMART. Alternatif yang digunakan adalah sembilan (9) sekolah jenjang SMP baik negeri maupun swasta. Kriteria yang digunakan mengacu pada instrument akreditasi perpustakaan sekolah yang dikeluarkan oleh Perpustakaan Nasional (Perpusnas) terdiri dari enam (6) kriteria yaitu koleksi, sarana dan prasarana perpustakaan, pelayanan perpustakaan, tenaga perpustakaan, penyelenggaraan dan pengelolaan perpustakaan, serta penguat. Hasil penelitian yang diperoleh untuk perpustakaan SMP adalah Sek 4, Sek 5 dan Sek 3 yang layak untuk diakreditasi
Penerapan Controlling Auto Light Dimmer Menggunakan Fuzzy Logic Pada Hidroponik Indoor
Authors: Fatimah Zahra Al-Gadri Putri , Kusumawati Weny Indah , Harianto - , Musayyanah -
Published: May 2023

Negara dengan tingkat kepadatan tinggi pasti membutuhkan tempat tinggal yang banyak. Hidroponik memakai media bukan tanah adalah salah satu solusinya. Hidroponik di dalam ruangan memerlukan pengganti cahaya matahari. Oleh karena itu, penelitian ini mengembangkan sistem untuk mengontrol intensitas cahaya tanaman hidroponik dengan metode yang inovatif. Alat ini menyesuaikan kondisi cahaya di dalam ruangan dan daya keluaran yang sesuai dengan intensitas cahaya lampu hidroponik melalui proses fuzzy logic controller. Tingkat kesalahan untuk data sensor dari Bh1750 adalah sekitar 4.05%. Ketika nilai aktuator dinaikkan, perangkat dimmer juga naik secara linier. Namun, angkanya tidak stabil antara 1 sampai 10, dan lebih dari 80. Karena kenaikan yang terus-menerus tinggi dan penurunan yang terus-menerus rendah, keluaran menjadi tidak stabil selama pengujian sistem fuzzy pada set point rendah. Namun pada set point tinggi, sistem berhasil menyesuaikannya ke nilai yang benar. Rise time 0.37 detik, SettlingMin 173.3300 lux, SettlingMax 945.83 lux, Overshoot 57.8%, dan Peak 956.7 lux, semua nilai di atas ada pada set point 600. Tanaman memiliki daun yang lebih lebar dan batang yang lebih tinggi apabila diberi set point tinggi, dibandingkan apabila diberi set point rendah.
Optimasi Bad Spot Area Jaringan 4G LTE Menggunakan Metode ACP Pada Wilayah Parit Putus
Authors: Aulia Rifki , Sutoyo - , Purnamirza Teddy , Mulyono -
Published: May 2023

Penyebaran teknologi 4G LTE masih belum optimal untuk semua wilayah di Indonesia salah satunya  berada pada objek peneltian ini yaitu wilayah Parit Putus Kabupaten Agam. Penelitian ini bertujuan melakukan optimasi pada daerah bad spot seperti Parit Putus agar menjadi optimal menggunakan metode mletode AClP (Alutomatic Celll Plalnning). Hal ini disebabkan hasil simulasi eksisting didapatkan nilai RSRP sebesar -105,88 dBm sampai dengan -97,38 dBm dan dikategorikan dalam kondisi kualitas jaringan yang buruk. Dikarenakan kurang optimalnya penempatan titik pemancar jaringan 4G LTE. Untluk lmengatasi perlmasalahan terseblut penelitian ini melakukan optimasi menggunakan meltode AClP (Alutomatic Celll Plalnning). Hasil penelitian menunjukkan penggunaan metode AlCP dapat menghitung secara otomatis tuning parameter seperti nilai azimuth dan tilting sehingga berhasil melakukan optimasi dengan adanya peningkatan nilai RSRP sebesar -85,08 dBm sampai dengan yang terbaik -81,50 dBm dengan kualitas jaringan berada pada kategori baik.
Family Resemblance: Displacement and Loss in Jane Austen’s Novels
Authors: Wiltshire John
Published: May 2023

The news that her family were to leave Steventon to live in Bath has often been thought a key moment in Jane Austen's life. She is said to have fainted in distress. This essay does not mine Austen's novels for clues to the author’s personal history, or suggest that the loss of a beloved home is directly reproduced in any of her novels, though this has been suggested, but argues instead that Austen’s fictions do show the impress of this traumatic experience in a more elusive and in-depth mode. In all of her novels, the motif of the loss of home plays a role, though quite differently in each. I draw on the philosopher Ludwig Wittgenstein’s concept of ‘family resemblance’ to provide a conceptual framework, and to illuminate the affinities between the novels and the author's life.
Energy security of Ukraine as the main criterion of effectiveness of the national economy functioning
Authors: Malinovska O. , Vysochanska M.
Published: May 2023

The article analyzes the energy security of Ukraine as the main criterion for the effectiveness of the functioning of the national economy today, its realities and prospects. It is stated that as of February 2022, the Ukrainian energy sector was one of the most powerful in Europe, and remains so now, despite significant damage as a result of the Russian invasion. In particular, Ukraine is among the top 10 European countries in terms of installed power generation capacity, among the top 3 gas producers, and has the largest underground gas storages in Europe. It was determined that the lack of a systematic approach to ensuring energy security is the main shortcoming of the current legislation of Ukraine. Complexes of legislative acts are developed by individual subjects in mutually inconsistent directions (regulation of energy markets, security of supply, standardization, physical protection, environmental requirements, etc.). It is substantiated that currently there are actually no tools for ensuring «energy security» and protection of Ukrainian subjects of the domestic energy market in the face of purposeful, politically motivated influen ce of other states, especially in view of the international obligations adopted by Ukraine regarding the construction of open, liberalized domestic energy markets. It has been proven that the purpose of introducing a new electricity market is to introduce competitive market functioning mechanisms, free choice of counterparties, and ensuring the consumer’s right to freely choose an electricity supplier. The law provides for various mechanisms for the purchase and sale of electricity — bilateral contracts, the day-ahead market and the intraday market to ensure sufficient volumes of electricity, and for the financial settlement of electricity imbalances, the balancing market and the market for auxiliary services are provided
Environmental and biological significance of the action of viper poison on the homeostasis of mammals
Authors: Mudrak O. , Maievskyi O. , Parfenyuk A. , Tkach Ye. , Tertychna O.
Published: May 2023

The article examines the ecological and biological significance of the action of animal poisons as an evolutionary adaptation that maximizes the adaptation of more than 250,000 species to the conditions of their habitat. It was found that animal poisons have a significant impact on the formation and course of various forms of connections in ecosystems, perform several ecological functions and are important biotic factors of the environment. The best-studied venomous animals have been found to be snakes, of over 3,800 different species, only a small number are highly venomous. The Viperidae family includes 101 species of poisonous snakes. In Europe, Vipera ammodytes, Vipera aspis, Vipera berus, Vipera latastei, Vipera seoanei and Vipera ursinii are the most dangerous species, their bites cause severe poisoning. In Ukraine, the genus Vipera is represented by the steppe viper (Vipera renardi (Cristoph, 1861)) and two subspecies of the common viper (Vipera berus (Linnaeus, 1758)) — Vipera berus berus and Nikolsky’s viper (Vipera berus nikolskii, Vedmederja Grubant et Rudaeva, 1986). The factors that affect the diversity of the composition of snake venom are given. It is noted that snake venoms are complex mixtures of proteins, peptides and low molecular weight substances, among which enzymes and non-enzymatic components are distinguished. The biological properties of snake venom depend significantly on the properties of its components, which have a wide range of effects on the general state of homeostasis of a living organism. A generalization of scientific data on the study of the chemical composition of the venom of Vipera renardi, Vipera berus nikolskii and Vipera berus berus and the effects of these venoms on the functioning of the mammalian body has been carried out. It was found that the venom of Vipera berus nikolskii is the most, and Vipera renardi — the least toxic for mammals (mice). The effect of Vipera berus nikolskii and Vipera berus berus venom on the proteolytic balance of individual organs of rats was evaluated. It is emphasized that viper venom toxins have a great, not yet fully developed potential in many scientific fields, therefore they deserve further practical research.
Hereditary angioedema (HAE) in Belgium: results from a national survey
Authors: Van der Poorten MM , Schrijvers R , Hermans C , Bartiaux M , Haerynck F , Lapeere H , Moutschen M , Michel O , Sabato V , Ebo DG , Van Gasse AL
Published: May 2023

Background

Hereditary angioedema (HAE) is a rare heritable disorder that is characterized by recurrent, circumscribed, nonpitting, nonpruritic, often painful subepithelial swellings of sudden unpredictable onset that generally fade during 48–72 h. Epidemiological data of hereditary angioedema patients in Belgium is lacking.

Methods

We set up a nation-wide, multicentric study involving the 8 Belgian hospitals known to follow-up patients with Type I and II HAE. All Belgium HAE patients were asked to fill out questionnaires that mainly covered demographic data, family history, and detailed information about diagnosis, treatment and burden of their Type I and II HAE.

Results

112 patients with type I or type II HAE could be included. Median delay between first symptoms and diagnosis was 7 years. 51% of patients had experienced pharyngeal or tongue swelling and 78% had experienced abdominal symptoms, both known to cause an important reduction in quality of life. 60% of symptomatic patients reported to receive long term prophylactic treatment. Human plasma-derived C1-esterase inhibitor concentrate was used by 56.3% of patients. 16.7% and 27.1% of patients used a 17-α-alkylated androgen and tranexamic acid as long term prophylactic therapy.

Conclusions

We present the first nation-wide epidemiological study regarding HAE in Belgium. Our data show that the morbidity of HAE is not to be underestimated. Knowledge and dissemination of this data is critical in raising awareness, encouraging development of therapies and optimising nationwide management.
The use of Moringa oleifera in ruminant feeding and its contribution to climate change mitigation
Authors: Amad Abdulkarim Abdulmageed , Zentek Jürgen
Published: May 2023

Livestock production in developing countries faces several difficulties such as a general shortage of feed resources, regional availability, and quality. Climate change further exacerbates these problems, leading to a massive reduction in ruminant productivity. Therefore, there is a need for the use of adaptable and resilient forage plants that can also contribute to reducing greenhouse gases. The Moringa oleifera tree is well known as an agroforestry tree and has adapted to growing in harsh conditions. It produces a high amount of biomass in a short period and contains high levels of nutrients and biologically active components. All parts of the Moringa tree are valuable and have multiple benefits and applications. Therefore, Moringa oleifera has great potential and can be used as a forage crop, storing carbon dioxide (CO2) and improving ruminant performance and the livelihoods of farmers in the tropics. This article aimed to present the results and findings of studies related to the use of Moringa in ruminant feed (cattle, sheep, and goats) and its contribution to climate protection. Several studies highlighted that M. oleifera can be used as green fodder either individually or in combination with other crops or concentrate feeds to improve the performance of ruminants, such as the growth rate, milk yield, and milk constituents, without negatively impacting animal health. This improvement in performance could be attributed to the favorable nutrient content in M. oleifera, delivering proteins in conjunction with bioactive compounds such as alkaloids, flavonoids, phenolics, glucosinolates, carotenoids, sterols, saponins, phenolic acids, tannins, and isothiocyanates. Furthermore, it has been shown that this plant can be produced in high yields and thus might be an excellent carbon dioxide sink to absorb and utilize carbon dioxide, reducing the anthropogenic load of carbon dioxide in the atmosphere. In addition, feeding cattle and other ruminants with M. oleifera leaves or seeds significantly decreases ruminal methane emissions, which could contribute to adapting to climate-friendly farming. Thus, the use of Moringa can make a sustainable contribution to strengthening animal production, especially in countries with limited feed resources.
Patient-derived organoids of lung cancer based on organoids-on-a-chip: enhancing clinical and translational applications
Authors: Zeng Xiao , Ma Qiong , Li Xue-Ke , You Li-Ting , Li Jia , Fu Xi , You Feng-Ming , Ren Yi-Feng
Published: May 2023

Lung cancer is one of the most common malignant tumors worldwide, with high morbidity and mortality due to significant individual characteristics and genetic heterogeneity. Personalized treatment is necessary to improve the overall survival rate of the patients. In recent years, the development of patient-derived organoids (PDOs) enables lung cancer diseases to be simulated in the real world, and closely reflects the pathophysiological characteristics of natural tumor occurrence and metastasis, highlighting their great potential in biomedical applications, translational medicine, and personalized treatment. However, the inherent defects of traditional organoids, such as poor stability, the tumor microenvironment with simple components and low throughput, limit their further clinical transformation and applications. In this review, we summarized the developments and applications of lung cancer PDOs and discussed the limitations of traditional PDOs in clinical transformation. Herein, we looked into the future and proposed that organoids-on-a-chip based on microfluidic technology are advantageous for personalized drug screening. In addition, combined with recent advances in lung cancer research, we explored the translational value and future development direction of organoids-on-a-chip in the precision treatment of lung cancer.
Dynamic pruning group equivariant network for motor imagery EEG recognition
Authors: Tang Xianlun , Zhang Wei , Wang Huiming , Wang Tianzhu , Tan Cong , Zou Mi , Xu Zihui
Published: May 2023

Introduction:The decoding of the motor imaging electroencephalogram (MI-EEG) is the most critical part of the brain-computer interface (BCI) system. However, the inherent complexity of EEG signals makes it challenging to analyze and model them.

Methods:In order to effectively extract and classify the features of EEG signals, a classification algorithm of motor imagery EEG signals based on dynamic pruning equal-variant group convolutional network is proposed. Group convolutional networks can learn powerful representations based on symmetric patterns, but they lack clear methods to learn meaningful relationships between them. The dynamic pruning equivariant group convolution proposed in this paper is used to enhance meaningful symmetric combinations and suppress unreasonable and misleading symmetric combinations. At the same time, a new dynamic pruning method is proposed to dynamically evaluate the importance of parameters, which can restore the pruned connections.

Results and Discussion:The experimental results show that the pruning group equivariant convolution network is superior to the traditional benchmark method in the benchmark motor imagery EEG data set. This research can also be transferred to other research areas.
Impact of a Lactobacillus dominant cervical microbiome, based on 16S-FAST profiling, on the reproductive outcomes of IVF patients
Authors: Guan Wenzheng , Dong Sitong , Wang Zhen , Jiao Jiao , Wang Xiuxia
Published: May 2023

Objective

This study assessed the impact of the cervical microbiome on reproductive outcomes in frozen embryo transfer (FET) patients.

Study design

This cross-sectional study included 120 women (aged 20–40 years) undergoing FET. A cervical sample obtained before embryo transfer was analyzed using 16S full-length assembly sequencing technology (16S-FAST), which detects full length 16S rDNA.

Results

We found that >48% of the identified Lactobacillus species were novel. The cervical microbiome was clustered into three cervical microbiome types (CMT): CMT1, dominated by L. crispatus; CMT2, dominated by L. iners; and CMT3, dominated by other bacteria. CMT1 had a significantly higher biochemical pregnancy rate (P=0.008) and clinical pregnancy rate (P=0.006) than CMT2 and CMT3. Logistic analysis showed that compared to CMT1, CMT2 and CMT3 were independent risk factors for biochemical pregnancy failure (odds ratio [OR]: 6.315, 95% confidence interval [CI]: 2.047-19.476, P=0.001; OR: 3.635, 95% CI: 1.084-12.189, P=0.037) and clinical pregnancy failure (OR: 4.883, 95% CI: 1.847-12.908, P=0.001; OR: 3.478, 95% CI: 1.221-9.911, P=0.020). A L. crispatus-dominated group as a diagnostic indicator of biochemical and clinical pregnancy positive had area under the curve (AUC) values of 0.651(P=0.008) and 0.645(P=0.007), respectively. Combining the cervical microbiome with embryonic stage optimized the diagnostic performance for biochemical and clinical pregnancy failure with AUC values of 0.743(P<0.001) and 0.702(P<0.001), respectively. Additionally, relative abundance of L. crispatus predicted biochemical pregnancy positive with AUC values of 0.679(P=0.002) and clinical pregnancy positive with AUC values of 0.659(P=0.003).

Conclusion

Cervical microbiome profiling using 16S-FAST enables stratification of the chance of becoming pregnant prior to FET. Knowledge of the cervical microbiota may enable couples to make more balanced decisions regarding the timing and continuation of FET treatment cycles.