bluuebunny/crossref_metadata_2025 huggingface dataset:
Breve recorrido por la literatura española del siglo XIX. De los románticos hasta la Generación del 98
Authors: Hernandéz Aline Kelly Vieira
Published: January 2018

No século XIX, o homem europeu encontra-se inflamado pelas ideias e sentimentos de liberdade, igualdade e fraternidade pregados pela Revolução francesa. Na Espanha, essas ideias e sentimentos são potencializados pela derrota das forças napoleônicas durante a Guerra de Independência espanhola. Toda essa gama de fortes emoções está plasmada na literatura da primeira metade do século. O Romantismo espanhol reflete todo esse sentimento de rebeldia, nacionalismo e necessidade de exaltação dos sentimentos, aliado ao desejo de viver intensamente. Na segunda metade do século, o Realismo espanhol surge como contraponto às ideias românticas. O Realismo apresenta-se como forma de observação da sociedade e seus costumes. Segundo os realistas, era preciso retratar a vida da forma como ela realmente acontece e não de maneira fantasiosa. Ao final do século, como uma maneira de reagir ao sentimento de decadência que se proliferava na Espanha, causado pelo chamado “Desastre do 98”, surge a “Geração do 98”, formada por um grupo de jovens escritores espanhóis preocupados pelo futuro e rumo que tomaria sua nação. No presente trabalho, temos como objetivo oferecer um panorama geral da literatura espanhola do século XIX. Não podendo colocar no trabalho todos os autores e obras deste século, tomamos como base alguns dos principais representantes de cada época e movimento literário. Os resultados deste trabalho destinam-se a colaborar em sua medida para os estudos literários sobre a literatura espanhola do século XIX.
Modeling the Impact of Interhospital Transfer Network Design on Stroke Outcomes in a Large City
Authors: Parikh Neal S. , Chatterjee Abhinaba , Díaz Iván , Pandya Ankur , Merkler Alexander E. , Gialdini Gino , Kummer Benjamin R. , Mir Saad A. , Lerario Michael P. , Fink Matthew E. , Navi Babak B. , Kamel Hooman
Published: January 2018

Background and Purpose—

We sought to model the effects of interhospital transfer network design on endovascular therapy eligibility and clinical outcomes of stroke because of large-vessel occlusion for the residents of a large city.

Methods—

We modeled 3 transfer network designs for New York City. In model A, patients were transferred from spoke hospitals to the closest hub hospitals with endovascular capabilities irrespective of hospital affiliation. In model B, which was considered the base case, patients were transferred to the closest affiliated hub hospitals. In model C, patients were transferred to the closest affiliated hospitals, and transfer times were adjusted to reflect full implementation of streamlined transfer protocols. Using Monte Carlo methods, we simulated the distributions of endovascular therapy eligibility and good functional outcomes (modified Rankin Scale score, 0–2) in these models.

Results—

In our models, 200 patients (interquartile range [IQR], 168–227) with a stroke amenable to endovascular therapy present to New York City spoke hospitals each year. Transferring patients to the closest hub hospital irrespective of affiliation (model A) resulted in 4 (IQR, 1–9) additional patients being eligible for endovascular therapy and an additional 1 (IQR, 0–2) patient achieving functional independence. Transferring patients only to affiliated hospitals while simulating full implementation of streamlined transfer protocols (model C) resulted in 17 (IQR, 3–41) additional patients being eligible for endovascular therapy and 3 (IQR, 1–8) additional patients achieving functional independence.

Conclusions—

Optimizing acute stroke transfer networks resulted in clinically small changes in population-level stroke outcomes in a dense, urban area.
From Theory of Accumulation to Social-Reproduction Theory
Authors: Čakardić Ankica
Published: January 2018

The paper functions as a contribution to feminist analyses that are methodologically based on Rosa Luxemburg’s critique of political economy and her understanding of capital accumulation, but also as a contribution to contemporary social-reproduction theory which aims to integrate Luxemburg’s legacy alongside that of Marx. The essay offers a sketch for a ‘Luxemburgian feminism’ consisting of (1) an overview of Luxemburg’s critique of bourgeois feminism and (2) a preliminary application of Luxemburg’s ‘dialectics of spatiality’ to contemporary social-reproduction theory. With Luxemburg’sThe Accumulation of Capitalin mind and her several essays on the so-called ‘women’s question’, we shall attempt to relate Luxemburg’s explanation of the dynamic link between capitalist and non-capitalist spatialities with the commodification of women’s reproductive labour.
New Elements for Introducing Symmetry in the Middle East Peace Process
Authors: Zartman I. William
Published: January 2018

This issue contains an examination of Palestinian-Israeli negotiations with an effort to break through the deadlock strategically. It analyzes the past record of failure and addresses the basic problem of asymmetry. Despite the solutions that have been advanced for all the specific issues, it is the forward-looking matter of trust that is the impediment to productive negotiations. The declaration of a Palestinian state and its recognition by the international community are now the basic elements necessary to break the asymmetry of the parties. A second element – allegedly favored by the Trump administration – is to reduce a symmetry by enlarging the playing field to include surrounding states, as proposed in the 2002 Arab Peace Initiative.
The taxonomic status of the South African straptail, Macruronus capensis Davies, 1950 (Pisces, Gadiformes, Macruronidae)
Authors: LESLIE ROBIN W. , GON OFER , GOUWS GAVIN
Published: January 2018

The first record of the straptail fish, genus Macruronus, from South Africa was based on a single specimen captured off the Atlantic Cape coast and described as a new species, M. capensis Davies 1950. Davies did not examine specimens of the other extant nominal species in the genus, but based his conclusions solely on references to the original descriptions of M. novaezelandiae (Hector 1870) and M. magellanicus Lönnberg 1907. We show that all of the characters used by Davies (1950) to distinguish M. capensis from its congeners are in fact shared by the other nominal species of this genus. We also present molecular evidence from a Macruronus specimen recently caught off South Africa to support the conclusion that M. capensis is a junior synonym of M. novaezelandiae.
Characteristics of the temperature–pressure field evolution of Middle Permian system in the northwest of Sichuan Basin
Authors: Xu Qiuchen , Qiu Nansheng , Liu Wen , Shen Anjiang , Wang Xiaofang , Zhang Guangwu
Published: January 2018

The Sichuan Basin is one of the richest oil and gas basins in China. The Middle Permian units (the Qixia and Maokou Formations) in the northwest Sichuan Basin have great potential for gas exploration. A new thermal history was reconstructed using the integrated thermal indicators of apatite and zircon (uranium–thorium)/helium ages, zircon fission tracks, and vitrinite reflectance data. The modeled results indicated that the northwest Sichuan Basin experienced gradual cooling, during which the heat flow at Middle Permian time (70–90 mW/m2) decreased to its current level of approximately 50 mW/m2. This study used basin modeling to reconstruct the paleo-pressure, which showed that the Middle Permian in the northwest Sichuan Basin generally developed overpressure. The pressure evolution of the Middle Permian can be divided into three stages: (1) a slight overpressure stage (T2–T3), (2) an intensive overpressure stage (J1–K2), and (3) an overpressure reduction stage (K2–present). Oil cracking and rapid tectonic subsidence are key factors that affect overpressure. The evolution of temperature–pressure has great significance with respect to hydrocarbon accumulation.
A Daughter of King Harsiese
Authors: Taylor John H.
Published: January 2018

The name of a daughter of the pharaoh Harsiese, incompletely preserved on a wooden fragment from Abydos (Philadelphia, Pennsylvania University Museum E.16186), is tentatively restored as tз-di-tз-nbt-hn.
Two Minor Monuments of Sety I
Authors: El-Saady Hassan M.
Published: January 2018

Publication of a stela depicting Sety I offering to Hathor of Bḥdt (Edinburgh RMS 1907.632), and of a faience shabti of the same king (Ashmolean 1952.445).
Epstein–Barr virus infection and type I interferon signature in patients with systemic lupus erythematosus
Authors: Han L , Zhang Y , Wang Q , Xin M , Yang K , Lei K , Sun M
Published: January 2018

Epstein–Barr (EB) virus infection has long been speculated to evoke systemic lupus erythematosus (SLE). Since a virus infection can induce interferon (IFN) system activation, we aimed to discover the relationship between the two in the progression of SLE in a Chinese inpatient cohort.

Methods

Peripheral blood mononuclear cells and sera were isolated from 116 SLE patients and 76 healthy controls. Antibodies against EBV-VCA (IgM and IgG) and EBNA (IgG) along with IFNα in patient sera were detected with enzyme-linked immunosorbent assays. The EB virus DNA load was detected by real-time quantitative polymerase chain reaction. Peripheral blood mononuclear cells both from patients and controls were isolated immediately. The mRNA from these samples was subjected to real-time PCR for the latent genes EBNA1, EBNA2 and LMP1 of EB virus, as well as four IFN-stimulated genes (ISGs) ( OASL, MX1, ISG15 and LY6E). The antibody results were used to determine the stage of EBV infection (lytic, latent, or previous).

Results

SLE patients had a higher rate of lytic infection defined as positive EBV-VCA IgM antibody (39.66% vs 10.53%, p = 0.027), but not the EB virus DNA load. Patients with lytic EB virus infection had higher SLEDAI scores than patients with non-lytic infection (15.24 ± 2.63 vs 13.79 ± 3.24, p = 0.012). LMP1 was the only EBV gene that had a higher expression level in SLE patients than in healthy controls (3.26 ± 2.95 vs 1.00 ± 2.89, p = 0.000). It was also positively correlated with SLEDAI scores ( r = 0.462, p = 0.000). Levels of IFNα and the four ISGs were all significantly higher in SLE patients than in healthy controls ( p < 0.05). LMP1 was positively correlated with the four ISGs ( r = 0.403 ∼ 0.494, p < 0.05) in SLE patients but not in healthy controls ( r = −0.153 ∼ 0.129, p > 0.05). Neither EBNA1 nor EBNA2 was correlated with the ISGs in SLE patients or in healthy controls.

Conclusions

The SLE patients had higher rates of lytic EB virus infection and higher latent gene LMP1 expression, which might be associated with the development and/or the progression of SLE via the type I IFN pathway. The underlying mechanism needs more study.
Mounting of Biomaterials for Use in Ophthalmic Cell Therapies
Authors: Harkin Damien G. , Dunphy Siobhan E. , Shadforth Audra M. A. , Dawson Rebecca A. , Walshe Jennifer , Zakaria Nadia
Published: January 2018

When used as scaffolds for cell therapies, biomaterials often present basic handling and logistical problems for scientists and surgeons alike. The quest for an appropriate mounting device for biomaterials is therefore a significant and common problem. In this review, we provide a detailed overview of the factors to consider when choosing an appropriate mounting device including those experienced during cell culture, quality assurance, and surgery. By way of example, we draw upon our combined experience in developing epithelial cell therapies for the treatment of eye diseases. We discuss commercially available options for achieving required goals and provide a detailed analysis of 4 experimental designs developed within our respective laboratories in Australia, the United Kingdom, and Belgium.
The Genetics of Depression and Manic-Depressive Disorder
Authors: McGuffin Peter , Katz Randy
Published: January 2018

Depressive disorders are more common in the relatives of depressed probands than in the population at large, and there is compelling evidence that the familial aggregation of bipolar disorder and severe unipolar depression is at least partly due to genetic factors. However, the evidence concerning ‘non-endogenous' depression is less clear, and family environment probably plays a stronger role. Much current research is focused on two areas: firstly, the mode of inheritance of manic-depressive illness, with the use of molecular biological techniques to detect and localise major genes; and secondly, the ways in which familial predisposition and environmental insults combine to produce depressive disorder.
Sexual Anxiety in Sexual Dysfunction
Authors: Patterson Diana G. , O'Gorman Ethna C.
Published: January 2018

Sexual anxiety was examined in 98 patients presenting with sexual dysfunction and 68 of their partners at a psychosexual clinic using the SOMA questionnaire. All patients had raised values for heterosexual anxiety. Female partners had raised values while male partners did not. This provides further evidence for the role of heterosexual anxiety in the aetiology and treatment of sexual dysfunction.
Measuring Behaviour Disorder in Mental Handicap
Authors: Lund Jens
Published: January 2018

By use of latent-trait item analysis (the Rasch model), the internal validity of the behaviour section of the MRC-HBS schedule was analysed. The set of behavioural symptoms in this rating scale was found to measure a one-dimensional structure. Thus addition of item scores provides a meaningful index. Such a numerical measure for the degree of behaviour disorder facilitates comparison between different patients or groups, and furthermore, forms the basis for quantitative description of the outcome of therapeutic intervention. A diagnosis of behaviour disorder was established in 17.2% of 302 mentally-handicapped adults. However, some kind of deviant behaviour was found in 41%, and was correlated with origin and degree of retardation, epilepsy, and place of living. The distribution of the symptoms strongly indicates that organic brain damage is a major aetiological cause.
A Family with Alzheimer's Disease
Authors: Patel S. V.
Published: January 2018

A family with clinically diagnosed Alzheimer's disease in three siblings is described. The inheritance of Alzheimer's disease in this pedigree is consistent with autosomal dominant inheritance.
Pericentric Inversion Chromosome 9 and Personality Disorder
Authors: Kumar H. V. , McMahon Kevin J. , Allman K. M. , McCaffrey B. , Rowan A.
Published: January 2018

A case of pericentric inversion chromosome 9 with an associated personality disorder is reported. There is justification for a more widespread cytogenetic screening of psychiatric disorders of this type.
A Hundred Years Ago: On the Therapeutic Value of Indian Hemp
Authors: Rollin Henry
Published: January 2018

I have during the last few years been accustomed to prescribe Indian hemp in many conditions, and this drug seems to me to deserve a better repute than it has obtained. In one form of insanity, more common in women than in men, and brought on usually by mental worry, often owing to the illness of a near relative or by a moral shock, the drug acts almost as a specific. In this affection the patient is depressed and apprehensive, she imagines that animals are after her or that someone wants to injure her. There is great mental confusion and mental loss, the patient is unable to carry on any conversation, and sometimes is unable to dress herself, the condition being one of acute dementia. I have notes of several such cases that have been cured by Indian hemp within a fortnight. I usually give 10–minim doses of the tincture thrice daily, combined with iron and strychnine. I prescribe also complete rest and plenty of food. The Indian hemp is an essential factor in the treatment, for without it the rapid recovery does not ensue: it seems to remove the mental distress and the restlessness.

Indian hemp has proved very useful in my hands in the treatment of melancholia and mania. I have also found this drug of great value in the treatment of chorea when arsenic fails, as it frequently does. It may be combined with chloral with advantage in such cases. In migraine the drug is also of great value; a pill containing ¼ gr. of the extract with or without a ¼ gr. of phosphide of zinc will often immediately check an attack, and if the pill be given twice a day continuously the severity and frequency of the attacks are often much diminished. I have met with patients who have been incapacitated for work from the frequency of the attacks, and who have been enabled by the use of Indian hemp to resume their employment. This drug is also a valuable gastric sedative in cases of gastric ulcer and gastrodynia. It may be combined with nitrate of silver, and it increases the efficacy of the latter. Its value is well known to asylum physicians, but it does not appear to have obtained the confidence of the profession generally. Indian hemp is also a very valuable hypnotic.
A Dementia that Spread Alzheimer and His Disease
Authors: Berrios German E.
Published: January 2018

Alzheimer's Disease. The Concept of Disease and the Construction of Medical Knowledge (Thesis Publishers, Amsterdam, $31, 357 pp., 1990) is by Rob Dillmann. The book is based upon his dissertation.
Holding Women Down
Authors: Knowles Jane
Published: January 2018

Ties that Bind: Essays on Mothering and Patriarchy (University of Chicago Press, $14.95 (pb), $29.95 (hb), 306 pp., 1990) is a collection of essays that originally appeared in Signs: Journal of Women in Culture and Society. It is edited by Jean F. O'Barr, Director of the Duke University Women's Studies Program and Editor of Signs, Deborah Pope, Associate Professor of English at Duke University and an Associate Editor of Signs, and Mary Wyer, Managing Editor of Signs.Women and Madness. The incarceration of Women in Nineteenth Century France, by YannicK Ripa, is published by Polity Press, Cambridge (£29.50, 175 pp., 1990). Dr Ripa teaches history at the University of Paris, Jussieu.
Comment on Institutionalism and Schizophrenia 30 Years On
Authors: Wing John
Published: January 2018

George Brown and I would like to congratulate David Curson and his colleagues on the conception and execution of this survey, but hope they are wrong in thinking that there can never be another such exercise. We are grateful to them and to the Editor for allowing us a brief preliminary comment. We have been sufficiently intrigued to want to go back to our data for new analyses, but this means reconstituting the original data base and will take some time.
Psychopharmacology and the Ethics of Resource Allocation
Authors: Bosanquet Nick , Zajdler Anna
Published: January 2018

Economists in the UK have developed a particular view of ethical choice which puts the main focus on short-term, static decisions. As resources are scarce, decisions have to compete (O'Donnell et al, 1988). Although economists have also stressed the moral imperative of improving efficiency, the theme of choice as inexorable has come through much more strongly. Economists in the UK have been more hesitant about giving any clear advice on how to deal with the special problems of supply efficiencies and professional monopoly in health services.
Bereavement: Studies of Grief in Adult Life: C. M. Parkes
Authors: Alexander David A.
Published: January 2018

When he submitted his dissertation on Morbid Grief Reactions: A Review of the Literature to the University of London in 1959, Parkes made his first major contribution to the study of grief and bereavement. There followed a series of publications (e.g. Parkes, 1965, 1971) which culminated in the first edition of the book reconsidered here. On my first reading of this book, I was reminded of Samuel Johnson's comment that “the two most engaging powers of an author are to make new things familiar, and familiar things new”. Parkes' descriptions of unusual reactions to loss are presented in a fashion which makes them feel reassuringly familiar, and those reactions which are more commonplace are described in a way which requires us to consider them anew.
Risk assessment
Authors: Holloway Frank
Published: January 2018

Reading about the assessment and management of risk began, in earnest, for me in 1993. Previously, I had assumed that good training in the management of suicidal patients, reasonable clinical skills, a high-quality community team and the rarely utilised option of referring worrying patients to the forensic psychiatrists together represented an adequate basis for practice in an inner-city catchment area. This naïve assumption was challenged by the popular and political reaction to the actions of Christopher Clunis and Ben Silcock in December 1992, both people with a schizophrenic illness known to services whose dangerous behaviour put them on the front page of newspapers in the UK. A groundbreaking textbook demonstrates that other medical specialities have, partly because of the threat of litigation, been more effective in analysing sources of risk and developing strategies to manage risk (Vincent, 1995). Improving quality is a central plank of the latest National Health Service reform (Department of Health, 1998). There is no doubt that the political driver for this is “the dark side of quality” (Vincent, 1997), how to deal with perceived or actual performance failures in health care such as the seminal ‘Bristol case’, in which cardiothoracic surgeons with an unusually high mortality rate in carrying out a complex procedure were found guilty of serious professional misconduct (Smith, 1998).
The Myth of Mental Illness: Thomas S. Szasz
Authors: Birtchnell John
Published: January 2018

Thomas Szasz is one of the most disliked names in contemporary psychiatry, and The Myth of Mental Illness is one of the most disapproved of books. It was Szasz's contention that illness can affect only the body and that there can be no such thing as an illness of the mind. He described mental illness as a metaphorical illness, maintaining that one can speak of a 'sick’ mind only in the same way as one can speak of a 'sick’ joke or a 'sick’ economy. He went on to argue that, if there is no mental illness, there can be no treatment for it, and no cure of it. There was, for him therefore, no medical, moral, or legal justification for involuntary psychiatric intervention or hospital admission. Such actions he considered to be crimes against humanity. He believed, after John Stuart Mill, that a man's body and soul are his own and not the state's, and that each individual has the right to do with his body whatever he pleases so long as it does not harm anyone else or infringe anybody else's rights.
Clinical Psychiatry: W. Mayer-Gross, E. Slater and M. Roth
Authors: Davison Kenneth
Published: January 2018

At first sight these three authors may seem an unlikely trio, but in the event their disparate experience and personalities proved to be complementary and the end product of their labours was a coherent and harmonious whole.
The Analysis of Therapeutic Groups: F. Kräupl Taylor
Authors: Crouch Eric
Published: January 2018

Frederick Kräupl Taylor came to the UK in 1939 at the age of 34 as a refugee from Czechoslovakia. He had specialised there in internal medicine, but could not initially gain medical registration here. He worked for a period in the pathology laboratory at the York Retreat and, in his spare time, studied mathematics, statistics, philosophy and psychology. Later he trained as a psychiatrist and was invited by Sir Aubrey Lewis to the Maudsley Hospital, where he was a consultant from 1948 until 1971.
Guide to Psychiatry: Myre Sim
Authors: O'Shea Brian
Published: January 2018

Myre Sim, who was born in Edinburgh in 1915 and now lives in self-imposed exile in Victoria, British Columbia, is not known for meekness. He still has strong views on issues such as abortion and AIDS, and his ability to get his thoughts into print has hardly diminished with increasing age. The strength of his opinions was graphically illustrated in a recent autobiographical sketch in the Psychiatric Bulletin (Sim, 1993). This Jew, who possessed “a better than average knowledge of … Holy Writ” by the time he was 16 years old, recalled with pleasure his laying a trap for the late Eliot Slater, whose “eugenic theories … had endeared [Slater] to the Hitler regime”. No wonder so many workers felt it difficult to engage in post-war genetic research.
Suicide
Authors: Morgan H. G.
Published: January 2018

As it is a special interest of mine, I read about suicide regularly. Most often this is because of the need to prepare a talk of some kind. I also read frequently in search of help in dealing with a clinical problem concerning a patient at risk. Less commonly, when I am not pressed for time, I am able to indulge in the luxury of reading for its own sake, out of sheer interest and curiosity, following up themes wherever they take me. Each of these approaches complements the others in an attempt to understand the complex phenomenon of suicide.
Psychogeriatrics
Authors: Pitt Brice
Published: January 2018

There has been an almost twentyfold increase in consultant psychogeriatricians in the UK in the past twenty years, and a comparable growth in the literature. In the early 1960s there were very few specifically psychogeriatric texts, and not all that many on related topics; now the reader is spoilt for choice.
Racial Differences in 21-Gene Recurrence Scores Among Patients With Hormone Receptor–Positive, Node-Negative Breast Cancer
Authors: Holowatyj Andreana N. , Cote Michele L. , Ruterbusch Julie J. , Ghanem Kristina , Schwartz Ann G. , Vigneau Fawn D. , Gorski David H. , Purrington Kristen S.
Published: January 2018

Purpose

The 21-gene recurrence score (RS) breast cancer assay is clinically used to quantify risk of 10-year distant recurrence by category (low, < 18; intermediate, 18 to 30; high, ≥ 31) for treatment management among women diagnosed with hormone receptor–positive, human epidermal growth factor receptor 2–negative, lymph node–negative breast cancer. Although non-Hispanic black (NHB) women have worse prognosis compared with non-Hispanic white (NHW) women, the equivalency of 21-gene RS across racial groups remains unknown.

Patients and Methods

Using the Metropolitan Detroit Cancer Surveillance System, we identified women who were diagnosed with hormone receptor–positive, human epidermal growth factor receptor 2–negative, lymph node–negative invasive breast cancer between 2010 and 2014. Multinomial logistic regression was used to quantify racial differences in 21-gene RS category.

Results

We identified 2,216 women (1,824 NHW and 392 NHB) with invasive breast cancer who met clinical guidelines for and underwent 21-gene RS testing. The mean RS was significantly higher in NHBs compared with NHWs (19.3 v 17.0, respectively; P = .0003), where NHBs were more likely to present with high-risk tumors compared with NHWs (14.8% v 8.3%, respectively; P = .0004). These differences were limited to patients younger than 65 years at diagnosis, among whom NHBs had significantly higher RS compared with NHWs (20 to 49 years: 23.6 v 17.3, respectively; P < .001 and 50 to 64 years: 19.6 v 17.4, respectively; P = .023). NHBs remained more likely to have high-risk tumors compared with NHWs after adjusting for age, clinical stage, tumor grade, and histology (odds ratio [OR], 1.75; 95% CI, 1.18 to 2.59).

Conclusion

NHBs who met clinical criteria for 21-gene RS testing had tumors with higher estimated risks of distant recurrence compared with NHWs. Further study is needed to elucidate whether differences in recurrence are observed for these women, which would have clinical implications for 21-gene RS calibration and treatment recommendations in NHB patients.
Fabricating an N-Doped Zn3B2O6 Polyhedral Composite Derived from a Zn-MOF with Phenylboronic Acid Ligands as Electrode Material for Sodium-Ion Batteries
Authors: Yang Boyi , Liu Hongbin , Lv Rui , Li Hui , Fu Xin , Su Jian , Liu Xin , Gu Wen
Published: January 2018

A polyhedral Zn-based MOF [Zn (B-BDC) (Dpy)] •H2O (B-BDC = 3, 5-Dicarboxyphenylboronic acid, Dpy = 4, 4′-Bipyridine) (CCDC: 1559247), named Zn-BDC, has been initially designed and constructed via hydrothermal method. Then, its crystal structure, morphology and thermal properties were confirmed by using a series of characterization methods. Furthermore, composite materials, denoted as Zn-BDC-T (T = pyrolysis temperature), were synthesized by directly calcining Zn-BDC under N2 atmosphere at different temperatures. Herein, Zn-BDC-800 was recognized as N-doped Zn3B2O6 composite according to characterization results. When the Zn-BDC-800 was used as electrode materials for sodium-ion batteries, it exhibited a maximum discharge specific capacity of 295.6 mAhg−1 at the current density of 50 mAg−1 and its coulombic efficiency still remained at 99% after 100 cycles. Thus, this N-doped Zn3B2O6 polyhedral composite derived from Zn-MOF has broad development prospects in the field of SIBs.
Recent advances in understanding and management of acquired thrombocytopenia
Authors: Nagalla Srikanth , Sarode Ravindra
Published: January 2018

There are numerous congenital and acquired causes of thrombocytopenia. Thrombocytopenia could be a result of decreased bone marrow production, increased consumption, increased destruction, splenic sequestration or a combination of these causes. In this review, we have focused on some of the serious acquired causes of thrombocytopenia. There have been some significant advances in our understanding of the pathophysiology, diagnostic testing, and treatment of immune thrombocytopenia, heparin-induced thrombocytopenia, thrombotic thrombocytopenic purpura, and atypical hemolytic uremic syndrome over the past five years. These advances have resulted in a significant decrease in mortality and morbidity of patients with these disorders. Despite these advances, we are still faced with numerous unanswered questions in the pathophysiology and management of these complex thrombocytopenic disorders.
Triplex target sites of MEG3 RNA-chromatin interactions
Authors: Antonov Ivan , Medvedeva Yulia A.
Published: January 2018

Many long noncoding RNAs are bound to chromatin. MEG3 binds to multiple different genomic locations, containing GA-rich motifs, and form RNA-DNA triplex structures. In this work, we test whether the MEG3 binding sites are specific enough to be regulated by a particular lncRNA. We show that at least in the case of MEG3, a subset of the triplex target sites (TTS) is able to hybridize with various different RNAs almost irrespectively of their sequences. Nowadays, the role of chromatin bound RNAs in the formation of 3D chromatin structure is actively discussed. We speculate that such universal TTSs may contribute to establishing long-distance chromosomal contacts.
A systematic review and critical analysis of cost-effectiveness studies for coronary artery disease treatment
Authors: McCreanor Victoria , Graves Nicholas , Barnett Adrian G , Parsonage Will , Merlo Gregory
Published: January 2018

Background: Cardiovascular disease remains the primary cause of death among Australians, despite dramatic improvements in overall cardiovascular health since the 1980s. Treating cardiovascular disease continues to place a significant economic strain on the Australian health care system, with direct healthcare costs exceeding those of any other disease. Coronary artery disease accounts for nearly one third of these costs and spending continues to rise.

A range of treatments is available for coronary artery disease yet evidence of cost-effectiveness is missing, particularly for the Australian context. Cost-effectiveness evidence can signal waste and inefficiency and so is essential for an efficient allocation of healthcare resources.

Methods: We used systematic review methods to search the literature across several electronic databases for economic evaluations of treatments for coronary artery disease.  We critically appraised the literature found in searches, both against the CHEERS statement for quality reporting of economic evaluations and in terms of its usefulness for policy and decision-makers.

Results: We retrieved a total of 308 references, 229 once duplicates were removed. Of these, 26 were excluded as they were not full papers (letters, editorials etc.), 55 were review papers, 50 were not cost-effectiveness analyses and 93 related to a highly specific patient sub-group or did not consider all treatment options.  This left five papers to be reviewed in full.

Conclusions: The current cost-effectiveness evidence does not support the increased use of PCI that has been seen in Australia and internationally. Due to problems with accessibility, clarity and relevance to policy and decision-makers, some otherwise very scientifically rigorous analyses have failed to generate any policy changes.
EXPERIMENTAL DATA OF THERMODYNAMIC PROCESSES IN THE MANSARD TYPE SITES FOR THE VERNALIZATION OF POTATOES
Authors: Смирнов Петр , Smirnov Petr , Виеру Татьяна , Vieru Tat'yana
Published: January 2018

The technology of vernalization of potatoes on the mansard structure sites, in particular, in the hayloft and fodder, is proposed for the conditions of agricultural small-scale production. The dimensions of the room, the experimental results of measurements of the daily temperature change and the ways of maintaining it, ensuring the necessary humidity are given. The date of the beginning of vernalization in the region is determined.
ECONOMIC EFFICIENCY OF FIELD CROP ROTATION IN OPTIMIZATION OF OF SOWING AREAS STRUCTURE
Authors: Чибис Валерий , Chibis Valeriy , Чибис Светлана , Chibis Svetlana , Кутышев Илья , Kutyshev Il'ya , Фалалеева Евгения , Falaleeva Evgeniya
Published: January 2018

In a long-term places, located on the experimental fields of Siberian Research Institute of Agriculture (Omsk), the schemes of field crop rotations were modernized by introducing oil crops (rapeseed, soybean) into rotation and replacing the repeated wheat crops with barley and oats. Accounting of grain crops productivity and accompanying observations were carried out in three field rotations of different lengths of rotation (four- and five-field) and on permanent sowing. The repetition of the experiments is fourfold. The system of agrotechnical measures recommended for the zone of the forest-steppe of Western Siberia was applied. The study of predecessors in the cultivation of crops for various purposes was carried out in field experiments using conventional methods. The humus content for rotation in the soil layer of 0-40 cm increased by 0.19% in the crop rotation “rapeseed - wheat spring wheat - barley - soybean - spring wheat”. The largest accumulation of humus (0.83%) was in the rotation “soybean - spring wheat - barley – oats”. During the years of research wheat productivity varied from 0.82 to 2.22 tons per hectare. Wheat was the first crop in all its predecessors to form grains, on average, by 0.3-0.5 tons per hectare, than the second crop. The yield of soybeans in the crop rotation was 1.23-1.78 tons per hectare. The productivity of rapeseed was low, its productivity over the years was 1.31 tons per hectare. Grain-fodder crops (barley, oats) averaged 0.4-0.6 tons per hectare, higher than the spring wheat productivity in the alternating rotation. The maximum yield of grain from a hectare of arable land was noted in the crop-steam rotation and amounted to 1.7 tons. An increase in the yield of feed-protein units was observed in crop rotations saturated with oil crops (rapeseed and soybean) and amounted to 3.4-4.0 tons per hectare. The economic calculation showed that the cultivation of field crops in the rotational crop rotation of “soybean - wheat - barley – oats” increased profitability by 44%, net income - by half, in comparison with the control variant. The obtained materials can be used to develop schemes of field crop rotations for the zone of the forest-steppe of Western Siberia.
INVESTIGATION OF LARCH FORESTS OF THE REPUBLIC OF TATARSTAN
Authors: Глушко Сергей , Glushko Sergey , Шайхразиев Шамиль , Shaykhraziev Shamil
Published: January 2018

In the area of our research, there are larch forests of artificial origin, there are no native larch forests. Larch is actively used in the forestry of the Republic of Tatarstan. The area of plantings of larch in the forest fund of Tatarstan has reached five thousand hectares. For the purpose of economic use of larch plantations, a typology of larch forests with exclusively artificial origin is being developed in the region. The typology of artificially created forests is of great practical importance. The results of the study of modern forest types are necessary for the development of the forest theory. Almost all modern forests are formed in the course of anthropogenic impact, we should state the spread of the anthropogenic forest formation process on the vast territories developed by man. The larch forests of the Republic of Tatarstan are a vivid example of anthropogenic forests, so their research will allow us to develop methods for classifying the majority of modern forests growing in the area of research.
FACTORS, AFFECTING THE RICE PRODUCTION EFFICIENCY
Authors: Абилдаева Жансая , Abildaeva Zhansaya
Published: January 2018

The article considers factors, affecting the efficiency of rice production in the agrarian sector of the economy. The modern tendencies of the rice market development and products of its processing are analyzed. It is asserted, that the efficiency of rice production in agricultural enterprises, is the result of the interaction of organizational-production, natural-limatic and social-economic factors, emphasizes the special role of introducing resource-saving and innovative technologies in rice growing. The need for the development of technologies is grounded, allowing rational use of the natural resource potential of a particular territory and a system of indicators, with the help of which the level and productivity of production is determined.
ASSESSMENT OF LAND USE CONDITIONS BY AGRICULTURAL ORGANIZATIONS OF OMSK REGION
Authors: Долматова Ольга , Dolmatova Ol'ga , Рогатнев Юрий , Rogatnev Yuriy
Published: January 2018

The article presents the results of applying the methodology for assessing the quality of land to ensure effective agricultural production. On the basis of correlation-regression analysis, indicators were chosen, that ensure high and medium tightness of communication, necessary for the formation of effective use of land by agricultural organizations in the context of municipal districts of Omsk region. Using the variation coefficient, which shows the relative measure of the spread of data, a set is defined. Based on the selected indicators, in accordance with the scaling factor scale, an index assessment of the conditions was carried out, which showed that the agricultural organizations of the steppe and southern forest-steppe zone of Omsk region are most favorable for natural conditions and land properties. Not so definitely, but, basically, the situation of advantage in the supply of labor resources to organizations of the steppe and southern forest-steppe zone was confirmed. However, in terms of the availability of the main means of production, the best indicators are for organizations of the southern forest-steppe zone, which in the end provided them with an advantage in the anthropogenic conditions of using the land in front of other zones. In general, the overall quality of land use conditions in the areas of the southern forest-steppe was higher than in other areas. This has had a decisive impact on the level of efficiency of agricultural land use in the districts of the region. In general, the areas of the southern forest-steppe have a higher efficiency of land use and the efficiency of crop production.
Multiple Exchange Property for M♮-Concave Functions and Valuated Matroids
Authors: Murota Kazuo
Published: January 2018

The multiple exchange property for matroid bases is generalized for valuated matroids and M-natural concave set functions. The proof is based on the Fenchel-type duality theorem in discrete convex analysis. The present result has an implication in economics: The strong no complementarities condition of Gul and Stacchetti is, in fact, equivalent to the gross substitutes condition of Kelso and Crawford.
Effect of Acute Coronary Syndrome Probability on Diagnostic and Prognostic Performance of High-Sensitivity Cardiac Troponin
Authors: Badertscher Patrick , Boeddinghaus Jasper , Nestelberger Thomas , Twerenbold Raphael , Wildi Karin , Sabti Zaid , Puelacher Christian , Rubini Giménez Maria , Pfäffli Julian , Flores Dayana , du Fay de Lavallaz Jeanne , Miró Òscar , Martin-Sanchez F Javier , Morawiec Beata , Lohrmann Jens , Buser Andreas , Keller Dagmar I , Geigy Nicolas , Reichlin Tobias , Mueller Christian ,   Other APACE Investigators and contributors to this manuscript include:, Cupa Janosch , Schumacher Lukas , Grimm Karin , Kozhuharov Nikola , Shrestha Samyut , Rentsch Katharina , López Beatriz , Yañez-Palma M C , Iglesias Sergio , Kawecki Damian , Ganovská Eva , Osswald Stefan
Published: January 2018

BACKGROUND

There is concern that high-sensitivity cardiac troponin (hs-cTn) may have low diagnostic accuracy in patients with low acute coronary syndrome (ACS) probability.

METHODS

We prospectively stratified patients presenting with acute chest discomfort to the emergency department (ED) into 3 groups according to their probability for ACS as assessed by the treating ED physician using a visual analog scale: ≤10%, 11% to 79%, and ≥80%, reviewing all information available at 90 min. hs-cTnT and hs-cTnI concentrations were determined in a blinded fashion. Two independent cardiologists adjudicated the final diagnosis.

RESULTS

Among 3828 patients eligible for analysis, 1189 patients had low (≤10%) probability for ACS. The incidence of non-ST-segment elevation myocardial infarction (NSTEMI) increased from 1.3% to 12.2% and 54.8% in patients with low, intermediate, and high ACS probability, respectively. The positive predictive value of hs-cTnT and hs-cTnI was low in patients with low ACS probability and increased with the incidence of NSTEMI, whereas the diagnostic accuracy of hs-cTnT and hs-cTnI for NSTEMI as quantified by the area under the curve (AUC) was very high and comparable among all 3 strata, e.g., AUC hs-cTnI, 0.96 (95% CI, 0.94–0.97); 0.87 (95% CI, 0.85–0.89); and 0.89 (95% CI, 0.87–0.92), respectively. Findings were validated using bootstrap analysis as an alternative methodology to define ACS probability. Similarly, higher hs-cTnT/I concentrations independently predicted all-cause mortality within 2 years (e.g., hs-cTnT hazard ratio, 1.39; 95% CI, 1.27–1.52), irrespective of ACS probability.

CONCLUSIONS

Diagnostic and prognostic accuracy and utility of hs-cTnT and hs-cTnI remain high in patients with acute chest discomfort and low ACS probability.

ClinicalTrials.gov Identifier: NCT00470587.
Blow-Up: The Powers of Scale
Authors: Moravánszky Ákos
Published: January 2018

During the decades following World War II, efforts were made to connect the rhetoric of the human scale with that of a superhuman, geographic or territorial scale. Aerial photography has opened up an all-encompassing view of the universe, presented in scalar sequences as the visual foundation for a new humanity. In the US, the large-scale regional project of the Tennessee Valley Authority (TVA). Attempts at integrating ecological, engineering, landscaping, architectural, and aesthetic concerns to realize a socio-economical vision were followed with enormous interest in Europe – before and after the war, in both West and East – and applauded by different political systems. Images popularizing the success of five-year plans and the heroism of nature transformation in the Soviet Union were also omnipresent themes in Western Europe. Ideas of transnational planning emerged in Europe shortly before the postwar continent was divided between the world powers. After the political partitioning of Europe into blocs, however, such plans had to be buried.
Tafuri on Hous-‘ing’: Housing History as City-making Praxis
Authors: Davidovici Irina
Published: January 2018

Manfredo Tafuri’s assessment of modernist housing projects as “islands of realised utopia” summarises dilemmas still faced in the production of European cities today. In his writings, Tafuri has consistently shown that housing is not only about industrial production but, fundamentally, social reproduction. Understood as a discursive practice, the history of housing as a history of ideas reveals fundamental mechanisms in the production of urban space. The historian’s perspective necessarily engages with cycles of cultural production and economic enterprise, intertwined in endless discourse.  On this basis, this article reviews the research methodologies distilled from Tafuri’s housing case studies in Berlin and Frankfurt, Vienna and Rome, in order to, firstly, re-evaluate the critical instruments of the housing historian, and secondly, trace their transformation as theoretical discourses into practices of city-making. Taking into account Tafuri’s notion of historical analysis as a contradictory, complex and constantly renewable operation, the paper proposes a revised understanding of twentieth-century housing history as a history of productive urban practices.
Living Hadis Dalam Tradisi Menjaga kubur Masyarakat Banjar Kabupaten Hulu Sungai Tengah Kalimantan Selatan
Authors: Jannah Miftahul
Published: January 2018

One of the phenomena of “Living Hadith” found in South Kalimantan is the tradition of watching over the tomb for a couple of days after the death of a person. It has been usually done in Banjar ethnic group and in particular in Hulu Sungai Tengah. This tradition is referred to the Hadith of Prophet Muhammad, although not all of them know the text of the Hadith. It is due to the fact that some got religious knowledge from the religious figure through their speeches. In the other hand, the guard of the tomb has different views, attitudes and purposes. While some had main purpose preserving of reciting the Qur’an in every moment, some others bore only granting the wish of other person. In some cases, they even consider this tradition as medium for the additional income.[Salah satu fenomena living hadis yang dapat ditemukan di Kalimantan Selatan adalah tradisi menjaga kubur selama beberapa hari yang diadakan setelah kematian seseorang, hal ini sudah biasa di kalangan masyarakat  Banjar pada umumnya, khususnya di Hulu Sungai Tengah, salah satu kabupaten di Kalimantan Selatan. Tradisi ini disinyalir dirujuk dari hadis Nabi Muhammad saw, meskipun tidak semuanya mengetahui persis teks hadis yang tersebut, karena pengetahuan yang berkembang didapat dari para tokoh agama melalui ceramah-ceramah. Para penunggu makam  mempunyai sikap atau pandangan serta tujuan yang berbeda-beda. Ada yang memang bertujuan untuk melestarikan bacaan al-Qur’an dalam setiap moment apapun, ada juga yang berniat sekedar mengabulkan hajat orang yang meminta tolong tersebut, bahkan ada juga yang memandang tradisi ini sebagai sarana untuk tambahan pemasukan komisi kantong.]