bluuebunny/crossref_metadata_2025 huggingface dataset:
Technical Skills and Competence of Sports Officiating Officials: Basis for an Action Plan
Authors: Sabillo Susan , Tiauzon Merry Jean , Bautista Mylene , Maguate Guarin
Published: November 2023

This research was conducted to determine the level of the technical skills and competence of sports officiating officials in schools division office of Escalante City during the School Year 2020-2021. Further, the study wanted to determine the level of the technical skills and competence of sports officiating officials when respondents are grouped and compared according to selected variables. Moreover, the result of the study also sought for an action plan. In view of the nature of the objectives of this study, the descriptive research design was used. A total of 82 sports officiating officials served as respondents of the study in the schools division office of Escalante City. The research instrument used in gathering data was a self-made questionnaire. To determine the profile of the respondents, data frequency and percentage were used. The study revealed that as assessed by the sports officiating officials when they are grouped according to the study’s variables, the results show a "high level" in all areas.Furthermore, the assessment of the level of technical skills of sports officiating officials in terms of areas indicated no significant difference when grouped and compared according to aforementioned variables. While the assessment on the level of competence of sports officiating officials in terms of areas of skills according to the level of accreditation and number of years as sports officiating officials indicated a significant difference and same is through in terms of area of training that all indicated with a significant difference when being grouped and compared according to aforementioned variables. Based on the findings of the study, the following relevant recommendations were advanced for consideration of those concerned: the findings of the study will be forwarded to the schools division office of Escalante City for them to be aware of the level of technical skills and competence of sports officiating officials. There is a strong need to improve certain areas in order that urgent and alternative measures can be planned and implemented. The division office can use the findings of this study in crafting interventions or proposing a plan of activities to satiate its policy lapses if there are any. School heads and supervisors in the schools division office of Escalante City may recommend doable interventions and propose a plan of activities via an action plan in order to formulate a viable roadmap to provide a clear guide to plans and programs to improve the level of technical skills and competence of sports officiating officials. Also, the proposed action plan must be considered in order to improve the said the level of technical skills and competence of sports officiating officials in the schools division office of Escalante City.
Élément quadrilatéral basé sur la déformation pour la flexion de plaques
Authors: Lamraoui Lazhar , Cherif Rebiai , Said Benlahmidi
Published: November 2023

Cette étude présente un nouvel élément fini quadrilatéral à quatre nœuds pour l'analyse linéaire de la flexion de plaques minces. L'élément a été développé en utilisant une approche basée sur la déformation qui suit la théorie de Kirchhoff pour les plaques minces. Chacun de ses quatre nœuds d'angle possède trois degrés de liberté, dont un déplacement transversal et deux rotations. Le champ de déplacement est dérivé de fonctions supposées pour diverses déformations qui satisfont aux équations de compatibilité, et les fonctions de déplacement sont obtenues en intégrant ces fonctions de déformation. Les résultats de plusieurs essais numériques démontrent la grande efficacité et l'excellente performance de ce nouvel élément.
Effect of Sukumara Gritham Residue Based Diet on Haemato-Biochemical Parameters of Malabari Goat Kids
Authors:   Department of Animal Nutrition, CVAS, Wayanad, Chacko Biju , Murugan S. Senthil
Published: November 2023

Eighteen Malabari kids of three to six months of age were divided into three dietary treatments (T1, T2 and T3) of six animals each, based on age, sex and body weight to study the effect of dietary incorporation of Sukumara gritham residue on their blood biochemical profile. The animals in treatment T1 (control) were given standard kid starter ration as per ICAR (2013) while in group T2 and T3, Sukumara gritham residue was included to the level of 10 and 20 per cent, respectively. The heamatological parameters viz., haemoglobin and biochemical parameters, viz., total protein, AST, ALT, total cholesterol, total triglycerides, blood urea nitrogen, creatinine and albumin were found to be similar in all the groups after 90 days of feeding trial. Hence, Sukumara gritham residue could be safely included in the kid starter ration up to 20 per cent level without any adverse effect on blood biochemical parameters.
Diversity and Distribution of Large Herbivore Mammals in Kawal Tiger Reserve, Telangana State
Authors:   Osmania University, Hyderabad-500004, Telangana State, India, Anagandhula Venkatesh , Padmaja Suricuchi
Published: November 2023

The usage of habitat, rate of growth, dispersion, and the reaction of a population to management activities are all factors in estimating the richness of wild animals. However, because there are so many real-world field issues, determining the densities of herbivore animals in the forest is challenging. The current study is conducted in Kawal Tiger Reserve, northeast of Telangana, to estimate the number of big herbivore mammals and learn more about how these animals use various habitats. The direct sighting and line transect methods were applied to collect systematic data. 7 species of large herbivore viz. Bluebull, Four-horned Antelope, Indian Gaur, Spotted Deer, Sambar Deer, Indian Gazelle, Wild boar were observed during the surveys. Based on the information, the habitat preferences of different large herbivore species in the study area is assessed. Results shows the richness of the species is abundant in the study area due to availability of sufficient food resources, sufficient water resources. No adverse increase or decrease in the quantity of sightings annually. Even if there have been a few local hunting occurrences, they are not noteworthy nor do they appear to have any impact on the extinction of species. It may also lamentably state that our carnivore density is really low.
Impact of Training on Modern Machineries and Improved Agricultural Technologies towards Cognitive Assessment of Farmers
Authors:   ADAC & RI, Trichy-620027. Tamil Nadu, A. Sakunthalai
Published: November 2023

In the era of fast changing technology, training has become an integrated part of investment for accelerating transfer of technology to people of all walks of life. The well-established network of organizations spread over the length and breadth of the country. The budget spent on training has tremendously increased over the past few years. with this background the study under taken at Trichy district, Tamil Nadu state of a country India by employing purposive sampling procedure. Agricultural Engineering College & Research Institute, Kumulur is one of the constituent colleges of Tamil Nadu Agricultural University located in Trichy. It is a pioneer institute in Tamil Nadu doing research on Agricultural Engineering technologies and Machinery. It is being chosen by the Tamil Nadu Govt. for state level capacity development trainings of farmers under the Agricultural Technology Management Agency and Agrl. Engineering Department (AED). Using simple random sampling procedure 10 farmers (trainees) were selected from 18 Districts of Tamil Nadu who were visited the institution during the study period. (180 sample size). The major objectives, as study of socioeconomic profile and knowledge assessment during pre and post training on Farm Machineries, Bio-energy, Agricultural Processing, Soil and Water Conservation, Drip irrigation and improved Agricultural sciences. Among 180 respondents, Majority of them were old age group (38.89 %) studied primary education (30.00 %) equally spread in marginal and small land holdings (around 75 %), possessed high level of farming experience (38.89 %) had medium level of extension agency contact (47.78 %), possessed medium level of Information seeking behaviour (53.89 %) with a medium level of Innovativeness (42.78 %). Knowledge test was assessed prior to training, among 180 respondents, Majority of farmers belonged to the medium level of knowledge category on all six categories and the after training knowledge test showed that the respondents belonged to low level were distributed in medium to high level of knowledge category and the medium level was elevated to high level category. The alternate hypothesis (H1)was proved through ‘ t’ test that there was a significant difference prevailed in the knowledge level of the respondents acquired through the trainings conducted on the recently developed Agrl. Technologies and modern machineries.
Modeling and Optimization of Chlorpyrifos by Fungi Isolated from Agricultural Soil, Elucidating their Degradation Pathways by LC-MS-Based Metabolomics
Authors:   University of Mysore, Manasagangotri, Mysore -570 006, Karnataka, India, Sosale Santhosh M. , N. S. Raju
Published: November 2023

Chlorpyrifos is a moderately hazardous insecticide to humans (Class II) by the World Health Organization (WHO) due to its acute toxicity still we are using cost-competitive and widely available suitable for various agro-climatic conditions, especially in arid regions of India. Our study explores the sustainable biodegradation pathways of biodegradation of chlorpyrifos-contaminated soils so that a novel chlorpyrifos-degrading fungus was isolated and identified as Aspergillus and Fusarium with the unique capability to degrade Chlorpyrifos. Identification of C1 and C2 two fungal strains, followed by isolation and characterization of CP and TCP degrading fungi through efficient biodegradation method. By LC-MS analysis the m/z values of sample TCP detected in culture medium and soil Aspergillus and Fusarium were able to completely mineralize Chlorpyrifos and its metabolite TCP from C1 and C2 culture grown in Mineral medium after 7 days of incubation soil without formation of any known intermediates. This study supports the idea that soils contaminated with Chlorpyrifos could be remedied effectively using fungi that break down Chlorpyrifos. Hence, this fungal consortium can be a valuable bio-augmenting agent to clean up Chlorpyrifos contaminated sites and helps in the sustainable management of natural resources.
QUALITY OF SERVICE AND SECURITY OF AERONAUTICAL COMMUNICATION NETWORKS
Authors:   ", PĂSCUȚOIU Ovidiu ,   Henri Coanda",   Air Force Academy, Brasov, Romania, UNGUREANU Maria-Daniela ,   “Politehnica” University of Bucharest, Romania
Published: November 2023

Aeronautical communication networks play a decisive role in the aviation industry, enabling real-time data exchange between various systems such ground stations, air traffic control and aircraft. Making sure that both requirements – high-quality-service and security – are met is mandatory to guarantee the efficiency, safety and reliability of aeronautical operations. This paper will go through a comprehensive inquiry of the quality of service and security of aeronautical communication and the relationship between them. The main focus of this paper is the security of aeronautical communications. The paper will examine the main types of aircraft communication types and will describe the cyber threats and the security measures applicable in order to mitigate the threats accordingly.
STUDY ON THE INFLUENCE OF TREATMENT PARAMETERS ON THE HARDNESS OF 6XXX SERIES ALUMINIUM ALLOYS
Authors:   ", STOICANESCU Maria ,   Transilvania",   University of Brasov, Romania
Published: November 2023

The appropriate application of heat treatments results in structural changes in alloys, and such changes enable the improvement of strength, hardness, ductility and other mechanical characteristics. This paper is mainly aimed at studying and analysing the influence of the quenching temperature and of the ageing holding time on the hardness of 6xxx series aluminium alloys. The thermal processes and parameters involved in the heat treatment of this alloy are studied, such as quenching and ageing, and the manner in which these treatments influence the properties of the resulting materials will be investigated.
Synthesis of new molecular hybrids with phenothiazine fragment from norambreinolide
Authors: Blaja Svetlana , Lungu Lidia , Kuchkova Kaleria , Ciocarlan Alexandru , Aricu Aculina
Published: November 2023

The known phenothiazine derivatives exhibit a wide spectrum of biological activities, including such as antiparasitic, antioxidant, anticancer, antiproliferative, antineoplastic, antimicrobial, etc. [1]. For this reason, terpeno-phenothiazine molecular hybrids represent one of the priority strategies of organic synthesis in the design of new bioactive compounds. Here are reported the results of the synthesis of new homodrimane hybrids with a phenothiazine fragment. Starting from (+)-sclareolide 1 the Δ8,13-bicyclohomofarnesoic acid 2 and 11-homodrim-6(8)-dien-12-oic acid 3 were synthesized in 6 and 5 steps in 62% and 81% overall yields, respectively [2,3]. Intermediate acyl chlorides 4 and 5 were generated in situ by treating acids 2 and 3 with oxalyl chloride in anhydrous benzene and then coupled with phenothiazine in the presence of triethylamine in methylene chloride on stirring to give hybrid phenothiazines 6 and 7 in depicted yields (see Scheme). The structures of all synthesized compounds were fully confirmed by spectral methods of analysis (IR, 1H, 13C and 15N NMR).
The dynamics of lavender and clary sage volatile oils adulteration on-air exposure
Authors: Lungu Lidia , Blaja Svetlana , Popescu Violeta , Ciocarlan Alexandru , Dragalin Ion , Aricu Aculina
Published: November 2023

Industrially produced Lavender (Lavandula angustifolia L.) and Clary sage (Salvia sclarea Mill.) essential oils are frequently used as ingredients in aromatherapy, traditional medicine, perfumery and cosmetics [1]. The chemical composition of both fresh volatile oils is mainly determined by unsaturated sesquiterpenic hydrocarbons and their oxygenated derivatives, but the main constituents are linalool 1 (22-34%) and linalyl acetate 2 (34-62%). The quality of volatile oils depends a lot on the storage conditions. Their adulteration can be caused by autooxidation, especially of terpenic unsaturated hydrocarbons and the resulted hydroperoxides are harmful, and can cause skin conditions, including cancer [2]. The aim of this study was the determination of the dynamics of mentioned essential oils adulteration on-air exposure, compared to the linalool 1 and linalyl acetate 2 standards, under ambient conditions (25-30ºC) for 20 weeks. During this time, both standards oxidized completely, but in the case of linalool and linalyl acetate in analysed oils the rates of oxidation are insignificantly (~8%) (see Fig.). Also, the results showed that the content of hydrocarbons decreased 16.9%→0.8% (Lavender oil), 7.9%→0.9% (C. sage oil), and that of oxygenated derivative increased 82.5%→98.6% and 82.5%→96.4%, respectively (see Table). The visible difference between the oxidation dynamics of linalool and linalyl acetate from the composition of volatile oils and standard samples is influenced by the competition with mono- and sesquiterpene components for molecular oxygen.
Pomolic acid from apple pomace: quantitative determination by heteronuclear two-dimentional QNMR and preparative isolation
Authors: Grinco Marina , Marina Alexandru , Birca Natalia , Boscanean Daniel , Barba Alic , Girbu Vladilena , Ungur Nicon , Kulcitki Veaceslav
Published: November 2023

Pomolic acid (PA) is a pentacyclic triterpenic acid isolated from apples by Brieskorn and Wunderer in 1967 [1]. Its highly relevant biological activity profile came recently into focus and there have been many reports on the content of PA in different plant sources [2]. Quite surprisingly, the general perception of low PA content in plants persists and this information hinders its broader investigation as a compound of pharmaceutical and nutraceutical potential. The main aim of the current work was quantitative determination of pomolic acid in apple pomace by two-dimensional heteronuclear NMR correlation spectroscopy. The dried and grinded apple pomace was extracted with solvents of moderate polarity, including ethanol, ethylacetate and dimethylcarbonate under conditions of ultrasound assisted extraction. The overall extraction time did not exceed 3 hours. Fractionated extracts were obtained on the separation of acidic and neutral part, followed by selective extraction with solvent series of increasing polarity (petroleum ether, dichloromethane, ethylacetate). The content of PA in the obtained extracts was determined basing on 2D NMR HSQC experiment according to a recently elaborated protocol [3]. The quantification was based on integration of cross peaks corresponding to selected protons of PA and methyl 2,4-dinitrobenzoate as internal standard. The results showed that the highest content of PA was observed in ethylacetate (13.7%) and dimethylcarbonate (9.5%) extracts. Ethanol extracts displayed lower PA content (4.6%) in extracts and higher material recovery as expressed in percentage PA of dry weight. It was also demonstrated that selective extracts fractionations can provide enriched PA samples on avoiding the laborious chromatographic separations. The broad availability of apple pomace as a by-product of apple juice production ensures an excellent perspective for the preparative isolation of pomolic acid which could be a valuable raw material for the food and pharmaceutical industries.
The spirocyclopropane with fragments of dehydroabietic acid and aminooxindole
Authors: Pogrebnoi Vsevolod , Sucman Natalia , Macaev Fliur
Published: November 2023

The abstract presents the synthesis of new highly functionalized spirocyclopropane with the fragment of natural compound – dehydroabietic acid 1 (DAK), which can be potentially active against some diseases.It is a known that spirocyclopropanes have anti-HIV activity [1]. From the other side there are a lot of natural and synthetical oxindoles with various biological activities [2]. And the last fact – that the high optical purity and the molecular structure of tricyclic diterpenoid 1 make it an attractive object for studying new various properties, such as the synthesis of new derivatives with the natural skeleton preservation [3]. Firstly, our approach was to isolate the DAK from natural sources and to transform into chloride 2. The next stage was the obtaining of 5-aminooxindole 6, which started from isatine 4, according to a known method [4]. The sequential three-stage synthesis of oxindole 5 [5] followed by classical reduction with hydrogen and 5 mol% of palladium on activated carbon [6] succeeded with 98% yield. And the final stage was the reaction of aminooxindole 6 with chloride 2 in dry chloroform, using as acceptor the excess Et3N. According to NMR spectrum, the desired product 7 is the mixture of diastereomers in ratio 1:1.
1,3-dipolar cycloaddition reactions of benzimidazolium-ylides to an activated symmetric alkyne
Authors: Diaconu Dumitrela , Mangalagiu Violeta , Amariucai-Mantu Dorina , Antoci Vasilichia , Danac Ramona , Mangalagiu Ionel
Published: November 2023

The cycloaddition reactions represent an important way to obtain cyclic structures and take place between two or more reactants containing double or triple bonds in the molecule. After Huisgen, the addition of 1,3-dipole to a dipolarophile, takes place through a concerted mechanism, when two  bonds are formed. [1,2] The purpose of this research is to study the Huisgen [3+2] dipolar cycloaddition reactions carried out in a conventional way (stirring at room temperature) and non-conventional way (ultrasonic irradiation), between benzimidazolium-ylides and an activated symmetric substituted alkyne - dimethyl acetylenedicarboxylate (DMAD) - as dipolarophile. [3-5] The Huisgen 3+2 dipolar cycloaddition reaction of benzimidazolium ylides to dymethyl acetylenedicarboxilate (DMAD) afford generating of three types of hybrid quinoline-benzimidazole cycloadducts and, according with the source of energy and solvent used the reactions pathway could be conducted selective.
Organizational and pedagogical conditions for teaching students types of foreign language communicative activity based on dictogloss
Authors: Aksenova Inga N.
Published: November 2023

Importance. The students’ foreign language communicative abilities development is the main goal of a foreign language teaching at a language university. The dictogloss as a means of a foreign language teaching is actively used for the speech skills progression, since it involves the participation of all four types of speech activities: reading, listening, speaking and writing. The dictogloss technique meets the requirements of a task-oriented approach to learning and involves the implementation of students’ independent activities, both individual and group, in the informational educational environment. However, in the modern methodical literature there are no installation requirements that determine the dictogloss use effectiveness as a means of a foreign language teaching. The purpose of the research is to identify a number of organizational and pedagogical conditions for teaching students types of foreign language communicative activity based on dictogloss.
Research Methods. Using the methods of scientific literature theoretical analysis on the research topic, as well as a comparative analysis of the conceptual provisions of modern approaches to teaching, the organizational and pedagogical conditions for teaching students types of foreign language communicative activity based on dictogloss are empirically identified.
Results and Discussion. The research describes a number of organizational and pedagogical conditions for teaching students types of foreign language communicative activity based on dictogloss. Mentioned conditions include the following aspects: a) students’ proficiency in a foreign language at level B1 and higher; b) compliance with a clearly defined sequence of learning stages; c) development of students and teachers linguocomputer competence; d) motivation of students to participate in language teaching through foreign language educational interaction; e) combined use of full-time and distance learning formats.
Conclusion. Teaching students types of foreign language communicative activity based on dictogloss is carried out in compliance with the above organizational and pedagogical conditions. The obtained results can be used in further research on the dictogloss integration in methods of a foreign language teaching.
Creating a healthy lifestyle for students through recreational aerobics
Authors: Platonova Yana V. , Korablev Yuri Y.
Published: November 2023

Importance. The problem of decreasing strength indicators in students is described. Insufficient use of strength exercises in the work with wrists and pre-shoulders in physical education classes in higher education institutions is revealed. Achieving of students optimal physical condition, increasing motor activity level, development of arm muscles and upper shoulder girdle strength abilities that solved through recreational aerobics are emphasized.
Research Methods. The students of the Derzhavin Tambov State University took part in the research. The measurement of muscle strength of the hands is carried out with a hand dynamometer, research of the level and development of static strength endurance is carried out with test for holding a medical ball weighing 2 kg in the outstretched hands.
Results and Discussion. The dynamometric measurements data of both right and left hands of junior women do not differ reliably from the results of senior women. The maximum strength of the women’s right arm is 25.11 kg and the left arm is 23.44 kg (p > 0.05). The average value in ball retention of the first year students is 85.31 s, the second year – 96.73 s, the third year – 112.62 s, the fourth year – 120.7 s. Comparison of the obtained test results shows a reliable improvement in the time of holding the ball in the outstretched hands among the senior students (p < 0.01). The obtained test values formed the basis of the scale for assessing the arms and upper shoulder girdle muscles static endurance development level of trainees.
Conclusion. The deficit of motor activity in students, most clearly manifested by the senior years of study, negatively affects the development of hand strength. The variety of hand movements used in the aerobic part of the recreational aerobics class, as well as work with muscles in static and dynamic modes in strength training, have a positive effect on increasing the static endurance of the hands and upper shoulder girdle muscles of students.
O microcrédito, política pública para gerar capital social
Authors: Pereira Raimundo Miguel dos Reis , Oliveira Lea Maria de Castro
Published: November 2023

O tema central do artigo é a política de microcrédito executada por duas instituições: uma governamental, o “Banco do Povo”; e outra não governamental, o “Instituto Tupinambá”. A ideia reflete sobre elementos teóricos e práticos que podem impactar na redução da pobreza e formar capital social aos usuários via microcrédito. A pesquisa exigiu a análise comparativa entre as instituições e coleta de dados primários e secundários. Objetivamente, foi preciso obter informações sobre o financiamento dos projetos e aplicar questionários para avaliar a inclusão e permanência de financiadores e cooperados. A pesquisa mostra que as instituições seguiram rumos opostos: enquanto o fundo público da Prefeitura de Belém desmontou a política de microcrédito, o Banco Comunitário Tupinambá vem funcionando, sem estímulo governamental. Os resultados da pesquisa mostraram que o fortalecimento do capital social em comunidades onde o microcrédito é implantado melhora a situação econômica da população de baixa renda.
Repercussões do racismo na alimentação e nutrição da população negra brasileira
Authors: Santos Ana Beatriz Almeida , Araújo André Dias , Almeida Ingra Gabriela de Oliveira , Vilasboas Gabriela dos Santos , Carvalho Vivian Carla Honorato dos Santos de
Published: November 2023

Introdução: O racismo trata-se de segregar um indivíduo ou coletivo por sua origem étnica e de persistir formas de exclusão, sendo considerado estrutural já que ele alcança todas as organizações da sociedade. A população negra possui barreiras referentes à saúde como consequência do racismo, as quais causam impactos importantes na alimentação e nutrição da população. Objetivo: descrever os aspectos que estruturam o racismo alimentar no Brasil e seus impactos na saúde da população negra. Métodos: Trata-se de um estudo de revisão de literatura, utilizando como metodologia a busca bibliográfica nas bases de dados do Scielo, Bireme e Periódico Capes, entre os períodos de 2012 a 2022, a fim de reconhecer estudos publicados sobre o tema. Resultados e Discussão: Foram selecionados 20 estudos que atenderam os critérios de elegibilidade. Foi possível observar que ser negro no Brasil está relacionado diretamente aos declínios do acesso a serviços fundamentais como saúde, educação, renda, valorização dos saberes ancestrais, o que gera impacto na possibilidade de viver com dignidade da população negra. Um espelho dessa situação são os dados de insegurança alimentar os quais expõem como a população negra é mais afetada por essa questão. Conclui-se que se faz necessário o aprimoramento dos programas de políticas públicas que atuem de fato no acesso dessa população aos serviços básicos para uma qualidade de vida ideal que todos merecem.
Heat-wave associated vibriosis in Russia, 2003-2021
Authors: LEONOV Vadim
Published: November 2023

Objectives: Noteworthy peaks of non-cholera vibriosis occurred in Russia’s Rostov and Volgograd regions in 2007 and 2010. The origins of these emergent vibrio cases have not been fully understood. Here, we investigate a possible link between the heat wave event and disease emergence. Methods: This study employed Pearson correlation and regression analyses to identify the linkage between ambient temperature and Vibrio cases. Results: The correlation test between the mean summer air temperatures for both regions and the Vibrio-infectious cases per year, shows a significant correlation between the mean summer temperature and the infection: r= 0.62 (p=0.023) for the Rostov region and r = 0.78 (p=0.012) for the Volgograd region. Conclusion: The heat waves in the summers of 2007 and 2010 suggest having facilitated the upsurge of V. cholerae non-cholera diseases. The warming tendency has to be considered in predicting outbreaks.

Keywords: Global warming, vibrio infections, Vibrio, Russia
Subsurface temperature change attributed to climate change at the northern latitude site of Kapuskasing, Canada
Authors:   nstituto de Física de Rosario IFIR CONICET/Universidad Nacional de Rosario, Rosario, S2000, Santa Fé, Argentina, Novara Ivan L. , Berdichevsky Daniel B. ,   nstituto de Física de Rosario IFIR CONICET/Universidad Nacional de Rosario, Rosario, S2000, Santa Fé, Argentina, Piacentini Ruben D ,   nstituto de Física de Rosario IFIR CONICET/Universidad Nacional de Rosario, Rosario, S2000, Santa Fé, Argentina
Published: November 2023

Subsurface temperatures have been measured in different regions of the world, usually near the surface up to a depth of about a hundred meters. In this work a forward model calculation for a Northern Hemisphere soil temperature site at Kapuskasing, Canada, is presented, employing the solution of the differential equation of heat conduction through a semi-infinite homogeneous solid, subject to surface boundary conditions determined by surface air temperature. In this way, a detailed analysis is made of the subsurface temperature as a function of ground depth and for the time interval ranging from 1970 to the future (including the next century), for different scenarios of climate change. From these results, it was possible to determine the following characteristic quantities: (a) the depth where the surface perturbation (practically) finishes (in the range of about 180-200 m); (b) the depth where the subsurface temperature changes its slope from negative to positive; (c) the temperature change at the surface for the years where data exist; (d) the thermal gradient at steady state in the starting year (1880); (e) the temperature differences extrapolated at surface and at a 20 m depth, this last value corresponding to the depth at which seasonal and diurnal temperature variations are negligible; (f) the heat flow at surface to the inner part of the soil attributed to climate change, and (g) the temperature changes at surface for the 100 years interval (1980-2080) and mainly for the next century (2080-2180), for each site and for each IPCC Representative Concentration Pathway (RCP) scenario. As an example, the impact of the change in mean annual soil temperature due to global warming in near-surface geothermal energy is described.
Autologous Faecal Microbiota Transplantation to Improve Outcomes of Haematopoietic Stem Cell Transplantation: Results of a Single-Centre Feasibility Study
Authors: Li Anna , Bowen Joanne Marie , Ball Imogen A , Wilson Sophie , Yong Angelina , Yeung David T , Lee Cindy H , Bryant Robert Venning V , Costello Samuel P , Ryan Feargal J. , Wardill Hannah R.
Published: November 2023

Haematopoietic stem cell transplantation (HSCT) is a curative approach for blood cancers, yet its efficacy is undermined by a range of acute and chronic complications. In light of mounting evidence to suggest that these complications are linked to a dysbiotic gut microbiome, we aimed to evaluate the feasibility of faecal microbiota transplantation (FMT) delivered during the acute phase after HSCT. Of note, this trial opted for FMT prepared using the individual’s own stool (autologous FMT) to mitigate risks of disease transmission from donor stool. Adults (>18 years) with multiple myeloma were recruited from a single centre. Stool was collected prior to starting first-line therapy. Patients that progressed to HSCT were offered FMT via 3 x re-tention enemas before day +5 (HSCT = day 0). Feasibility was determined by recruitment rate, number and volume of enemas administered, and retention time. Longitudinally collected stool samples were also col-lected to explore the influence of auto-FMT using 16S rRNA gene sequencing. N=4 (2F:2M) participants received auto-FMT in 12 months. Participants received an average of 2.25(1-3) enemas (43.67(25-50)mL total, retained for an average of 60.78(10-145)minutes). No AEs, attributed to the FMT, were identified. Although minimum requirements were met for the volume and retention of auto-FMT, recruitment was significantly impacted by the logistical challenges of pre-therapy stool collection. This ultimately under-mined the feasibility of this trial and suggests that third party (donor) FMT should be prioritised.
Nanofiber-Based Systems for Regenerative Medicine: A Technical Note
Authors: Khoshnevisan Kamyar
Published: November 2023

Nanofiber-based systems have emerged as a groundbreaking approach in the field of regenerative medicine, offering immense potential for tissue engineering and regenerative therapies. These systems, composed of nanoscale fibers, provide a unique platform for mimicking/bio-mimicking the complex structures and functionalities of native tissues, enabling the regeneration of injured tissues. This letter aims to provide a brief overview of nanofiber-based systems in regenerative medicine, discovering their importance, design, and fabrication techniques, characterization, biocompatibility, applications, challenges, and future directions as well as discussing key concepts and techniques involved in the development of this innovative tool.
Light and Shadows in Newborn Screening for Lysosomal Storage Disorders: Eight Years of Experience in Northeast Italy
Authors: Gragnaniello Vincenza , Cazzorla Chiara , Gueraldi Daniela , Puma Andrea , Loro Christian , Porcù Elena , Stornaiuolo Maria , Miglioranza Paolo , Salviati Leonardo , Burlina Alessandro P , Burlina Alberto B
Published: November 2023

In the last two decades, the development of high-throughput diagnostic methods and availabil-ity of effective treatments has increased interest in newborn screening for lysosomal storage disorders. However, long-term follow-up experience is needed to clearly identify risks, benefits and challenges.
We report our 8-year experience of screening and follow up on about 250,000 neonates screened for four lysosomal storage diseases (Pompe disease, mucopolysaccharidosis type I, Fabry dis-ease, Gaucher disease), using enzyme activity assay by tandem mass spectrometry, and bi-omarker quantification as second tier test.
Among the 126 positive newborns (0.051%), 51 infants were confirmed as affected (positive pre-dictive value 40%), with an overall incidence of 1:4,874. Of these, 3 infantile-onset Pompe dis-ease, 2 neonatal-onset Gaucher disease and 4 mucopolysaccharidosis type I patients were imme-diately treated. Furthermore, another four Gaucher disease patients needed treatment in the first years of life.
Our study demonstrated the feasibility and effectiveness of newborn screening for lysosomal storage diseases. Early diagnosis and treatment allow the achievement of better patient out-comes. Challenges such as false positive rates, the diagnosis of variants of uncertain significance or late-onset forms, and the lack of treatment for neuronopathic forms, should be addressed.
IDENTIFIKASI HAMA DAN PENYAKIT TANAMAN JAGUNG DENGAN MENGGUNAKAN METODE KLASIFIKASI SUPPORT VECTOR MACHINE (SVM)
Authors: Khotimah Bain Khusnul , Setiawan Eko , Sasmeka Verdi , Fridayanti Aulya , Maulana Ikbar , Mifta Zulfida Arwinda
Published: November 2023

Produksi hasil panen tanaman Jagung di Madura dipengaruhi oleh adanya wabah Hama dan penyakit, sehingga menyebabkan produksi jagung menurun. Permasalahan tersebut salah satunya dapat diatasi dengan adanya mengidentifikasi awal gejala tanaman yang terserang hama dan penyakit dengan menggunakan klasifikasi machine learning.  Penelitian ini menggunakan metode Support Vector Machine (SVM) untuk klasifikasi hama dan penyakit pada tanaman jagung. Sedangkan data yang digunakan berupa 200 data jenis kategori dengan 25 variabel pertanyaan, yang didiagnosa berupa penyakit, dan hama tanaman jagung. Metode ini menggunakan fungsi pemisah  supaya lebih optimal ketika memisahkan jenis data dari dua kelas yang berbeda. SVM dapat mendeteksi jenis hama dan penyakit tanaman jagung dengan masukan gejala dari pengguna. Penelitian ini telah menghasilkan akurasi  sistem yaitu perbedaan hasil perhitungan identifikasi dengan hasil perhitungan pada perbandingan data 60:40 dengan menggunakan perubahan parameter σ dan d, dengan memilih fungsi Kernel Gaussian Radial Basic telah menghasilkan akurasi klasifikasi senilai 94.29%.
Signatures of Syndepositional Seismic Effects in Aeronian Marine Clastic Sediments in Western Gorny Altai
Authors: Sennikov N.V.
Published: November 2023

––The Aeronian clastic sediments in the Gorny Altai area bear signatures of past seismic effects (paleo-seismites). Sedimentary structures produced by brittle deformation (breccias) span the level of the upper convolutus graptolite zone and the lower sedgwicki zone. They coexist with soft-sediment deformation structures (SSDS), such as turbated and rolled layers, bumpy layer boundaries, etc. At the final deposition stage, the rocks were deformed during seismically-triggered landsliding and were shed into a submarine canyon, with formation of rolls (pseudo-conglomerate).
Research on fluid identification method under strong reflection shielding
Authors: Yang Wei , Xiao Fucheng , Yuan Jingyi , Sun Chong , Zhu Shijun
Published: November 2023

This study aims to develop a framework to overcome the geophysical challenge that it is difficult to identify the fracture-cavity reservoir shielded under strong reflection interface, with the prominent advantages of empirical mode decomposition (EMD) method in processing nonlinear and non-stationary signals. First, to avoid the “mode aliasing” problem in the decomposition process, the fast ensemble empirical mode decomposition (FEEMD) is employed to decompose seismic information“”. Then, the local linear embedding algorithm (LLE) is applied to remove the strong reflection background in each component retaining the feature of original data and extract useful signals that finally reconstruct the optimized signals. Based on the aforementioned procedure, FEEMD-LLE method is used to analyze the spectrum and fluidity attributes along the layer under the strong reflection interface. The results indicate that FEEMD-LLE method is effective in fluid identification and prediction, while removing the shielding effect of strong reflection on fracture-cavity reservoir and maintaining the fidelity and amplitude preservation of seismic signals. Empirically, the seismic data of a study area in Tahe oilfield is used as the fluid detection object, and the detection results successfully predict the fluid shielded by the strong reflection, which is consistent with the actual drilling interpretation results, verifying the application advantage of the method in this paper to remove the strong reflection background.
Uncertainty-biased molecular dynamics for learning uniformly accurate interatomic potentials
Authors: Zaverkin Viktor , Holzmüller David , Christiansen Henrik , Errica Federico , Alesiani Francesco , Takamoto Makoto , Niepert Mathias , Kästner Johannes
Published: November 2023

Efficiently creating a concise but comprehensive data set for training machine-learned interatomic potentials (MLIPs) is an under-explored problem. Active learning (AL), which uses either biased or unbiased molecular dynamics (MD) simulations to generate candidate pools, aims to address this objective. Existing biased and unbiased MD simulations, however, are prone to miss either rare events or extrapolative regions—areas of the configurational space where unreliable predictions are made. Simultaneously exploring both regions is necessary for developing uniformly accurate MLIPs. In this work, we demonstrate that MD simulations, when biased by the MLIP’s energy uncertainty, effectively capture extrapolative regions and rare events without the need to know a priori the system’s transition temperatures and pressures. Exploiting automatic differentiation, we enhance bias-forces-driven MD simulations by introducing the concept of bias stress. We also employ calibrated ensemble-free uncertainties derived from sketched gradient features to yield MLIPs with similar or better accuracy than ensemble-based uncertainty methods at a lower computational cost. We use the proposed uncertainty-driven AL approach to develop MLIPs for two benchmark systems: alanine dipeptide and MIL-53(Al). Compared to MLIPs trained with conventional MD simulations, MLIPs trained with the proposed data-generation method more accurately represent the relevant configurational space for both atomic systems.
Capability Review of X.509v3 with Link Maximum Transmission Unit in Public Key Infrastructure
Authors: Abhishek Kunal
Published: November 2023

The X.509v3 is widely accepted digital certificate format proposed by the International Telecommunication Union (ITU) for Internet applications. The size of the X.509v3 certificate with its extensions has now grown up significantly in the range of 1518 bytes to 200 kilobytes which is much beyond the Maximum Transmission Unit (MTU) sizes of Internet Protocol (IP) based link-layer technologies. The large certificate size leads to poor network performance due to the limited link-layer MTU sizes that causes IP fragmentation and longer Round Trip Time (RTT). We present a comprehensive capability review of X.509v3 digital certificate in light of the link-layer MTU sizes. We also investigate if this certificate format is capable to integrate and process multi-kilobytes long post-quantum key and signature as well as if this certificate size can be reduced to merely few hundred bytes for use by the resource-constrained Internet of Things (IoT) devices to realize a Public Key Infrastructure (PKI) while keeping the network performance intact. In particular, we review the X.509v3 certificate transmission over the Ethernet and IPv6 over 6Low-power Wireless Personal Area Networks (6LoWPAN) networks with a focus on their link MTUs. We also present our recommendations to efficiently handle transmission of both large and small extreme sizes of the X.509v3 certificates over the link-layer MTUs of these technologies.
Research on Multi-source DC microgrid Distributed Group Control Strategy for Pumping Well Cluste
Authors: Yue Jixiang , Sun Zhenhua , Li Haoguang , Zhu Wenyu , Li Fengming , Wang Zhenjie
Published: November 2023

Due to the pumping units' dual role as alternating loads and new energy sources, multi-source DC microgrid pumping unit well clusters experience increased fluctuation in voltage and power as well as peak and valley values that are superimposed. This work presents a distributed cooperation strategy based on the grouping weighted moving average algorithm for pumping unit well groups in multi-source DC microgrid. Centralized control program is implanted in the RTU of the single well controller of each pumping unit, and the communication of each single well is realized by SCADA system to construct the distributed well group system. The real-time power values of the pumping well group are calculated by grouping the power values and granting weighted weights to each group, using the total power fluctuation threshold of the well group as the control target, and further using a weighted moving average algorithm to predict the next power value and form a table of predicted real-time power spectra. According to the power value in the community power spectrum table, the inverter frequency is proportionally adjusted downward to achieve the power peak before deceleration to reach; after crossing the power peak, the frequency is raised in the same way to accelerate the compensation to achieve the power valley before acceleration to reach, that is, acceleration compensation, and finally achieve the power peak and valley values of the bus system to level off, and further learn to reach the set impulse, and finally form a stable impulse. Through laboratory testing and field application in Shengli XIN-11 block application proved: the group control software module not only effectively suppresses the active power peak and valley values and voltage fluctuations of the bus system, the active power fluctuation rate range decreases by more than 70%, the DC bus voltage fluctuation range decreases by more than 80%, but also reduces active power by about 6% without increasing the cost of new hardware.
Patient-Specific Functional Liver Segments based on Centerline Classification of the Hepatic and Portal Veins
Authors: d'Albenzio Gabriella , Meng Ruoyan , Aghayan Davit , Pelanis Egidijus , Sakinis Tomas , Solberg Ole Vegard , Tangen Geir Arne , Kumar Rahul P. , Elle Ole Jakob , Edwin Bjørn , Palomar Rafael
Published: November 2023

Couinaud's liver segment classification has served as the standard basis for liver surgery planning for nearly seven decades. While providing a systematic framework by dividing the liver into eight segments, its reliance on fixed planar boundaries may not always align with individual liver anatomical variations. In this study, we propose a new method for classifying liver functional segments. By integrating patient-specific liver morphology, 3D vascular system, and user-defined landmarks, our approach offers greater flexibility in classifying the liver while respecting individual anatomical variations. We conducted a comprehensive assessment of our method, comparing it with two widely used liver classification techniques: conventional plane-based and portal vein-based classifications. Our results demonstrate that our method's flexibility extends beyond conventional software. By enabling the inclusion of both hepatic and portal veins, including peripheral branches, our approach deviates from the classical Couinaud classification. Importantly, our findings indicate that our approach not only overcomes the limitations of traditional methods but also provides a more precise and surgery-ready definition of liver segments, particularly in complex cases involving segments 5 and 8. Furthermore, feedback from liver surgery specialists highlights its potential benefits, including improved visualization in complex cases and better assessment of vascular perfusion territories.
tfQMRgpu: A GPU-accelerated linear solver with block-sparse complex result matrix
Authors: Baumeister Paul F , Nassyr Stepan
Published: November 2023

Linear solvers are a central component of many applications in physics and engineering. In this work we present a software package for simultaneously solving with multiple right-hand sides using the vast compute performance and memory bandwidth of graphical processors. Using the transpose-free quasi minimal residual method iterative linear solving does not require the implementation of an adjoint operator. This C++/CUDA software packet has two ways of being employed. The precompiled version of this library offers linear solving for single and double precision block-sparse complex matrices with interfaces to various programming languages, in particular C, Fortran, Python and Julia. Furthermore, the core algorithm is available for custom implementations of any linear operator as a C++ header-only library. We showcase a matrix-free approach of a custom operator for a finite-difference stencil application solving the three-dimensional Helmholtz equation and compare the performance of the matrix-free approach against the block-sparse matrix version, both on NVIDIA hardware.
MSC Classification: 15-04