bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH MODEL PEMBELAJARAN COOPERATIVE INTEGRATED READING AND COMPOSITION TERHADAP KEMAMPUAN BERPIKIR KRITIS SISWA DALAM PEMBELAJARAN IPS
Authors: Putri Puspita Nasrianti , Mulyani Srie , Caturiasari Jennyta
Published: April 2024

This research is motivated by the implementation of learning that does not involve students in being active and teachers have not used indicators of critical thinking skills. This is one of the causes of students critical thinking skills in social studies learning to be less than optimal. This research uses a quantitative approach with the type of pre-experiment research and the research design One-Groups Control Pretest-Posttest Design. The sample used in the study was 27 class VB students. Data collection techniques using written tests and documentation. The test instrument is a description item consisting of 10 items to measure critical thinking skills.The research results show that: (1) there is an increase before and after using the Cooperative Integrated Reading and Composition model. This is evidenced by an average pretest score of 57.69 and an average posttest score of 81.23 (2) there is a significant influence, this is evidenced by a determination test (r square) of 0.594 which means that the Cooperative Integrated model has a large influence Reading and Composition on students' critical thinking skills is 59.4% and the average N-Gain is 0.56 which means that there is an average increase using the Cooperative Integrated Reading and Composition model in the medium category.
PENERAPAN MODEL PROBLEM BASED LEARNING PADA PEMBELAJARAN TEMATIK MUATAN BAHASA INDONESIA KELAS III SEKOLAH DASAR
Authors: Farisia Hernik , SetyoBudi Fadia Dwi Adis , Chafsoh Nabila Priyanka , Apriliyanti Vanny
Published: April 2024

Kurangnya kemampuan guru dalam memberikan peluang pada peserta didik supaya aktif memiliki dampak pada keterampilan berbahasa mereka. Selain itu, tidak adanya motivasi yang dimiliki peserta didik juga mengakibatkan hal tersebut. Pembelajaran tematik muatan Bahasa Indonesia perlu dilaksanakan secara variatif dan inovatif agar penguasaan kompetensi yang dimiliki peserta didik menjadi optimal. Dalam penelitian ini menggunakan teknik analisis data deskriptif kualitatif. Dalam karya ini digunakan literature review, mencari penelitian di berbagai sumber literatur berupa buku, artikel, jurnal atau dokumen yang berkaitan dengan masalah yang diteliti. Metode ini diperoleh rujukan dari 10 tahun terakhir artikel atau jurnal yang berkaitan dengan penerapan model Problem Based Learning pada pembelajaran tematik muatan Bahasa Indonesia. Dengan menggunakan model Problem Based Learning akan membantu guru dalam mengatasi permasalahan yang ada. Pada kondisi awal, peserta didik diarahkan agar mengidentifikasi suatu permasalahan. Selanjutnya, mereka harus menemukan solusi melalui kegiatan penyelidikan. Terbukti dari hasil penelitian bahwasanya model ini dapat meningkatkan keaktifan peserta didik, sekaligus keterampilan berbahasa mereka. Sebab peserta didik dapat mengutarakan pendapatnya dengan keterampilan dalam berbahasa.
ANALISIS BIBLIOMETRIK TERHADAP FACE AND VOICE RECOGNITION
Authors: Rahayu Sri , Rukli Rukli , Quraisy Andi
Published: April 2024

Technology in the digital age like today, not only makes it easier for humans to interact remotely, but technology is now also widely used as a form of self-recognition. Automatic self-recognition systems are needed in today's information age. Automatic self-recognition can be done using body parts known as biometrics. Biometrics is a self-recognition technology that uses body parts or human behavior. There are several common biometric methods that are often used for self-identification, one of which is face and voice. Therefore, this research aims to find out the development of research with the theme of phase and voice recognition on artificial neural networks from 2019-2023. The type of research used is qualitative with bibliometric analysis. The research used as a search engine is Publish Or Perish (POP) with data collection done through Google Sholar indexed publications. The number of articles analyzed was limited to 200 data in the form of journals. This was done with the aim of narrowing the search for the field of artificial neuroscience, especially in the phase and voice recognition, but only 120 data were fulfilled. The results showed that the most connected topic was neural network. The results of this study can be utilized by future researchers to explore and develop the topic of phase and voice regocnition.
MENGANALISIS MODEL-MODEL PEMBELAJARAN YANG EFEKTIF BERBASIS ICT (INFORMATION AND COMMUNICATION OF TECHNOLOGY) DI ERA REVOLUSI INDUSTRI 5.0
Authors: Uzzahra Naya , Nafisa Sayyida , Titin Titin , Yuniarti Anisyah
Published: April 2024

Seiring dengan berkembangnya teknologi, ICT telah menjadi fasilitas pembelajaran modern yang sangat populer di dunia dan telah dikembangkan menjadi berbagai model untuk membantu guru dan siswa dalam memudahkan kegiatan pembelajaran menjadi lebih aktif dan interaktif. Maka dari itu, pemerintah dan instansi pendidikan perlu memberikan perhatian penuh terhadap perkembangan teknologi saat ini dan memastikan bahwa penggunaan ICT dibidang pendidikan dapat memberikan manfaat yang maksimal bagi peserta didik dan pendidik. Era revolusi industri 5.0 dalam dunia pendidikan adalah konsep yang berkembang di masa depan dan belum mencapai tahap implementasi. Namun, di era revolusi industri 5.0 diharapkan akan menghadirkan transformasi lebih lanjut dengan perkembangan seperti kecerdasan buatan, teknologi pembelajaran online, serta metode pengajaran yang inovatif. Tujuan adanya analisis model-model pembelajaran berbasis ICT adalah untuk mengetahui kelebihan dan kekurangan setiap model, serta memikirkan kapan dan dimana model-model ini dapat mendukung pembelajaran sehingga lebih efektif.
ANALISIS PENGGUNAAN SMARTPHONE TERHADAP PRESTASI AKADEMIK SISWA SD
Authors: Chaerani Rahmi , Suciningsih Suciningsih , Malindra Kelana Faleh , Rakhmania Raisa
Published: April 2024

Smartphones have an influence on technological advances that cover several aspects that are basically limited to communication tools. Now smartphones are the main needs for each individual that will continue to develop to facilitate daily activities. Smartphones can have positive and negative effects on their users. If the smartphone is used properly, it will have a positive impact, but if the smartphone is not used properly, it will have a negative impact on its users. The use of smartphones is not only from adults or teenagers, but many elementary school children are already using smartphones to facilitate their activities. The purpose of this study was to analyze the effect of smartphone use on academic achievement of elementary school students. The method used in this research is a literature study by reviewing 10 selected articles. The data collection technique was carried out by reviewing and analyzing data in the form of literature review so as to obtain conclusions. The results showed that smartphones can cause student learning achievement to decline due to the lack of proper utilization of smartphones. Students will be less motivated to learn if they are addicted to smartphones, causing a decrease in concentration while studying and a lack of interest in learning.
PENERAPAN PENDIDIKAN KARAKTER DALAM PEMBELAJARAN MATEMATIKA UNTUK MENGEMBANGKAN KARAKTER PESERTA DIDIK DI MADRASAH IBTIDAIYAH
Authors: Masturoh Oktiani Mersiliana , Nofikusumawati Peni Nur Robiah
Published: April 2024

The purpose of writing this article is to analyze further the application of Character Education in mathematical learning to develop the character of learners in MI, because when viewed there are still many learners' behaviors that are still minimal in character education. In accordance with the objectives of Indonesian Education stated in law no. 20 of 2003 that the purpose of national Education is to develop the potential of learners. Hence the importance of Character Education early on, that is, starting from the bench of Madrasah Ibtidaiyah. Later, for the method used in this study is the literature study method. The results of literature studies such as journals, articles, or books in this study are able to support character education in general as well as specifically as in mathematical learning. The application of character education in mathematical learning to develop the character education of learners adapted to learning adapted to the needs of learners in mathematical learning as well as their objectives.
DESIGNING ENGLISH WORKSHEET FOR THE STUDENTS OF ISLAMIC JUNIOR HIGH SCHOOL IN JAMBI
Authors: Nurhasanah Amalia , Mahmudah Faiqah , Winarti Muncar
Published: April 2024

This article aims at elaborating the process of designing a worksheet to teach English specifically speaking and writing skills for the students of an Islamic Junior High School in Jambi. This was a research and development inquiry in which the researchers applied Dick and Carey’s model (in Gall and Borg, 2003). List of questions for interview, questionnaires, observation checklist, and documentation were used as instruments to obtain the data. Based on the need analysis, it was found that the English materials expected by the eighth grade students were: (a) picture-based material which were colorful and attractive, (b) simple English texts with understandable questions, (c) well-understood instruction, and (d) using familiar words. The final design of the material consisted of three chapters with different themes.
Misi yang Ramah dan Estetis: Rekonstruksi Misiologi Pentakostal Melalui Perspektif Hospitalitas dan Teopoetik
Authors: Hasiholan Anggi Maringan
Published: April 2024

Abstract. The Pentecostal mission inherited the way of colonialism in conveying the Good News to humanity. The imposition and universalisation of the doctrine to every tribe, culture, religion, and group is a common way to do it. Conversion from other religions and proselytization from other Christian sects become the achievement and measure of the mission's success. This article examines the mission's authentic meaning that can change the paradigm of conversion and proselytization as the mission's success. I used the perspective of hospitality and theopoetics to construct the authentic meaning of the Pentecostal mission. The research method used is constructive theology by Gordon Dester Kaufman. The research result showed that hospitality contributes to the courage to destroy the dividing walls of tribes, races, religions, and groups. Meanwhile, with inspiration, imagination, sensation, and beauty principles, theopoetics can provide space for little voices and encouragement to carry out social transformation.Abstrak. Misi Pentakostal mewarisi cara ekspansi agama dalam menyampaikan Kabar Baik kepada umat manusia. Pemaksaan dan universalisasi doktrin kepada setiap suku, budaya, agama, dan golongan menjadi cara yang lumrah dilakukan. Konversi dari agama lain dan proselitasi dari aliran Kristen yang lain menjadi pencapaian dan ukuran keberhasilan misi. Artikel ini bertujuan untuk mengkaji makna otentik misi yang dapat mengubah paradigma konversi dan proselitasi sebagai keberhasilan misi. Penulis menggunakan perspektif hospitalitas dan teopoetik dari Gordon Dester Kaufman untuk mengonstruksi makna otentik misi Pentakostal. ­ Hasil penelitian menunjukkan bahwa hospitalitas berkontribusi bagi keberanian menghancurkan tembok pemisah suku, ras, agama, dan golongan. Sementara itu, dengan prinsip inspirasi, imajinasi, sensasi, dan keindahan, teopoetik mampu memberi ruang bagi suara minor dan dorongan untuk melakukan transformasi sosial.
The Homeless Liturgy: Meliturgikan Ratapan, Harapan, dan Transformasi Kaum Miskin
Authors: Hutagalung Fitry Hanna
Published: April 2024

Abstract. Poverty is a well-known and complex issue. Poverty has a bad impact on the poor. Thus, poverty is the duty of society, including the church. The purpose of this paper is to investigate the relationship between liturgy and poverty. The homeless liturgy is the phrase selected to describe liturgical practices in the face of poverty. This essay was conducted by socio-liturgical studies and field research. This essay suggests that the homeless liturgy is a manifestation of the church's preference for the poor, which speaks hope-lament, liberation, and promotes transformation.Abstrak. Kemiskinan adalah permasalahan klasik dan kompleks. Kemiskinan berdampak pada keberlangsungan hidup orang banyak. Untuk itu, kemiskinan bukan hanya menjadi tanggung jawab negara, melainkan juga masyarakat dan termasuk gereja. Tulisan ini bertujuan untuk mengeksplorasi relasi-interaksi liturgi dan kemiskinan. Homeless liturgy merupakan istilah yang dipilih untuk merepresentasikan praktik berliturgi di tengah-tengah kemiskinan. Melalui kajian sosio-liturgis dan penelitian lapangan, artikel ini menyimpulkan bahwa homeless liturgy merupakan wujud sikap keberpihakan gereja terhadap mereka yang miskin, yang menyuarakan harapan-ratapan, yang membebaskan dan menggerakkan transformasi.
Experimental Comparison of Manufacturing Parameters in Automotive Friction Materials
Authors: Akbulut Furkan , Mutlu İbrahim
Published: April 2024

In this study, a fixed automotive friction material content was determined and the mechanical and tribological effects of manufacturing parameters on friction materials were investigated. Parameters; pre-forming time (1-3-5 min) and pre-forming pressure (8-10-12 MPa), hot pressing time (5-10-15 min) hot pressing pressure (8-10-12 MPa) and hot pressing temperature (125-150-175 °C), curing time (4-8-12 h) and curing temperature (120-150-180 °C) were determined. The friction test of the produced samples was carried out under 0.551 MPa pressure and 7 m/s rotation speed for 90 min. In addition, the average COF, friction stability, specific wear rate, density and hardness values of the samples were calculated. According to the results obtained, the average COF value increased as the pre-forming time and pressure increased. The lowest specific wear rate among all specimens was calculated as 7.622x10-6 cm3/Nm in PFP-12 specimen. With the increase in hot pressing time, the tribological properties of friction materials improved. The highest friction stability among all samples was calculated as 79.42% in the HPT-15 sample. Although there was an increase in the average COF value with increasing hot pressing pressure and temperature, the specific wear rates increased in these parameters. The highest average COF value among all samples was obtained in the CT-12 sample with a value of 0.553. The specific wear rate increased with the increase in curing time and temperature. The highest specific wear rate among all samples was calculated 10,743x10-6 cm3/Nm in the CTe-180 sample. Finally, it has been suggested that 3 min for pre-forming time, 12 MPa for pre-forming pressure; 15 min for hot pressing time, 12 MPa for hot pressing pressure, and 150°C for hot pressing temperature; and a curing time of 8 h and curing temperature of 150 °C may be sufficient.
Criterios ecográficos diagnósticos de neoplasia maligna en el nódulo tiroideo: correlación con la punción por aspiración con aguja fina y la anatomía patológica
Authors: Chala Andrés Ignacio , Pava Rafael , Franco Humberto Ignacio , Álvarez Andrés , Franco Armando
Published: April 2024

Introducción. La ecografía de tiroides ha mejorado la certeza diagnóstica para neoplasia maligna del nódulo tiroideo. Es importante definir qué nódulos requieren biopsia por aspiración con aguja fina (BACAF) para disminuir el costo de un procedimiento innecesario y evitar que pase inadvertido el diagnóstico de neoplasia maligna.

Objetivo. Validar los criterios ecográficos de neoplasia maligna que indican la punción por aspiración con aguja fina de tiroides.

Materiales y métodos. Se diseñó un estudio prospectivo a tres años para evaluar la concordancia entre los hallazgos ecográficos y la punción por aspiración con aguja fina de tiroides comparada con el estudio final de histopatología. Se evaluó la sensibilidad, la especificidad, el valor diagnóstico positivo y negativo, la concordancia medida por el coeficiente kappa y el coeficiente de correlación.

Resultados. Se estudiaron 1.467 pacientes, 10,2 % hombres y 89,8 % mujeres, con edades entre los 10 y los 95 años; el tamaño promedio del nódulo fue de 16 mm. Un total de 623 requirieron tiroidectomía; al resto se les hizo seguimiento por ecografía. Se presentaron 269 carcinomas papilares, 14 foliculares, 4 indiferenciados, 159 bocios, 74 adenomas y 101 tiroiditis. Se obtuvo sensibilidad de 86,4 %, especificidad de 89,4 %, valor diagnóstico de un resultado positivo de 87,5 % y uno negativo de 84,1 %. Los hallazgos ecográficos relacionados con cáncer fueron: hipoecogenicidad, microcalcificaciones, papilas y flujo intranodular. Individualmente, la concordancia fue baja, pero con la combinación de hipoecogenicidad, microcalcificaciones y papilas fue media y, con la adición de aumento del flujo intranodular, resultó alta.

Conclusiones. La combinación de hipoecogenicidad, microcalcificaciones, papilas y alto flujo intranodular tiene alta concordancia con neoplasia maligna; sin embargo, cada criterio por separado no la tiene, y no pueden usarse individualmente para predecir o descartar neoplasia maligna.
Diet quality by KIDMED index and eating disorders in an overweight pediatric population
Authors:   Laboratoire de Nutrition Clinique et Métabolique, Faculté des Sciences de la Nature et de la Vie. Université Oran 1 Ahmed Benbella, BP 1524 El M’Naouer 31000 Oran, BELKHAROUBI Roumaissa , MEDJAHDI Nedjwa , KADDOUR Farah F. , BOUZIANE NEDJADI Karim , BOUCHENAK Malika ,   Service de Pédiatrie Amilcar Cabral, CHU-Oran, Oran, Algérie
Published: April 2024

Introduction. Obesity has become one of the most prevalent nutritional disor-ders, characterized by excess adipose tissue with physical and psychosocial conse-quences, affecting negatively quality of life. Objectives. To study the diet quality and identify eating disorders (TCA) in a pediatric population suffering from overweight. Population and methods. Thirty patients (16 girls/14 boys), aged 5 to 17 years, were recruited from the Pediatric Department of Oran University Hospital. Anthropometric parameters were measured. Physical activity level as well as diet quality by the KIDMED index were evaluated. The Binge Eating Scale (ADO-BED), and the Child-Three Factor Eating Questionnaire (CTFEQ) were used to identify possible eating disorders. Results. Obesity was noted in 77% of the pediatric population, while 23% were overweight. Only 40% of patients practiced sporting activity, while 60% had sedentary behavior on weekends. The KIDMED score calculation showed low adherence to the Mediterranean diet (RM), in 83% of the population. Although the ADO-BED questionnaire indicated a low risk of binge episodes in 97% of patients, CTFEQ data revealed that 67% had signs of loss of eating control, 7% had cognitive restriction, and 7% had emotional eating. Conclusion. Poor dietary habits, associated with sedentary lifestyle, are observed in the studied overweight pediatric population. These results highlight the need for nutritional intervention and psychological care for these patients.
THE RELATIONSHIP BETWEEN THE ROLE OF THE MIDWIFE AND DISTANCE TO HEALTH FACILITIES WITH POSTPARTUM VISITS IN PUSKESMAS WORKING AREA TANJUNG BUNTUNG BATAM CITY IN 2023
Authors: Poppy Aprilia  , Mona Rahayu Putri  , Didi Yunaspi
Published: April 2024

Cakupan pelayanan nifas lengkap tahun 2022 di Kepri masih terbilang cukup jauh dari target yang tercapai yaitu 90,7%. Kepri hanya mencapai target sebesar 78,3%. Penelitian bertujuan untuk mengetahui Hubungan Peran Bidan dan Jarak ke Fasilitas Kesehatan dengan Kunjungan Nifas di Wilayah Kerja Puskesmas Tanjung Buntung Kota Batam Tahun 2023. Menggunakan penelitian korelasional dengan rencana cross sectional yang melibatkan 65 ibu nifas, populasi ibu nifas di kota batam tahun 2022. Pengambilan sampel menggunakan teknik purposive sampling . Alat ukur adalah kuesioner yang telah baku. Hasil distribusi frekuensi menunjukkan sebagian besar ibu nifas melakukan kunjungan nifas tidak lengkap 44 (67,7%), peran bidan cukup 47 (72,3%), jarak ke fasilitas kesehatan jauh 33 (50,8%). Hasil uji statistik nilai Chi-Square   ( p value = 0,000 < 0,05). Diharapkan ibu nifas melakukan kunjungan nifas lengkap minimal 4 kali untuk mencegah terjadinya komplikasi pada masa nifas.

 

 

Kata Kunci : Kunjungan Nifas, Peran Bidan, Jarak ke Fasilitas Kesehatan
EDUCATIONAL PACKAGE FOR DETECTION AND STIMULATION OF TODDLER DEVELOPMENT
Authors: Aisyah Risqi Dewi , Ersila Wahyu , Faradisi Firman
Published: April 2024

Approximately 52.9 million children under 5 globally have developmental disorders. Early detection is crucial for addressing these issues. This study aimed to assess the impact of a detection and stimulation education package on parental knowledge and attitudes. Using a pseudo-experimental, cross-sectional design with cluster random sampling, 78 respondents were analyzed via T-test. Results revealed significant improvement in mothers' knowledge and attitudes following the education package (p=0.001). Providing such packages enhances awareness and understanding of toddler development. Health professionals, particularly midwives, are advised to collaborate in early detection and stimulation programs, ensuring comprehensive education for parents. This collaborative effort can significantly contribute to addressing developmental challenges in young children.
KONSEKUENSI ASEAN VISION 2020 TERHADAP KESEMPATAN KERJA PENYANDANG DISABILITAS DI INDONESIA
Authors:   Universitas Diponegoro, Alrasyid Nafi
Published: April 2024

ASEAN VISION 2020 mempunyai tujuan untuk menciptakan kesatuan wilayah ekonomi di Asia Tenggara yang secara simultan meningkatkan kesejahteraan bagi negara-negara anggotanya. Sejak dicanangkan pada tahun 1997, negara-negara anggota ASEAN telah didorong untuk mengubah kebijakan baik internasional maupun dalam negeri guna mendukung tujuan utama tersebut. Hasilnya, penduduk Asia Tenggara kini mempunyai kesempatan yang lebih luas untuk bekerja di kesatuan wilayah tersebut. Baru-baru ini, Indonesia, sebagai salah satu dari sebelas negara anggota lainnya, telah mengubah kebijakan ketenagakerjaan guna mengakomodasi pekerja luar negeri untuk bekerja di wilayah Indonesia. Di sisi lain, Indonesia mempunyai permasalahan panjang dan belum terselesaikan terkait dengan pengangguran dan kemiskinan. Orang-orang penyandang disabilitas merupakan kelompok rentan yang terdekat dengan pengangguran dan kemiskinan. Kebijakan ketenagakerjaan yang baru hanya berfokus pada kebebasan pasar kerja namun tidak memberikan pengamanan dan/atau jaminan kepada penyandang disabilitas untuk mengakses pasar kerja tersebut. Mempertimbangkan permasalahan tersebut, perubahan pandangan tentang pekerjaan bagi penyandang disabilitas sangat segera diperlukan
PERLINDUNGAN ASET DIGITAL PADA ERA METAVERSE DALAM PERSPEKTIF HUKUM POSITIF DI INDONESIA
Authors:   Fakultas Ilmu Sosial Universitas Harapan Bangsa, Indonesia, Ruhtiani Maya , Naili Yuris Tri ,   Fakultas Ilmu Sosial Universitas Harapan Bangsa, Indonesia, Wahyuni Hesti Ayu ,   Fakultas Ilmu Sosial Universitas Harapan Bangsa, Indonesia, Purwono Purwono ,   Fakultas Ilmu Sosial Universitas Harapan Bangsa, Indonesia
Published: April 2024

Penelitian ini mengkaji mengenai permasalahan tindak kejahatan terhadap aset digital pada era metaverse dan bagaimana perlindungan hukum terhadap aset digitalnya. Tujuan penelitian ini untuk mengetahui bagaimana perlindungan hukum terhadap aset digital pada era metaverse. Artikel ini diteliti dengan menggunakan jenis penelitian yuridis normatif. Dimana pada pembahasannya penelitian ini memprioritaskan kepada pengkajian penerapan norma hukum positif atau kaidah hukum yang diterapkan di Indonesia. Perlindungan hukum terhadap aset digital pada era metaverse berkaitan dengan ancaman keamanan dan privasi terhadap identitas, data, privasi, jaringan, ekonomi, tata kelola, dan efek fisik/sosial. Tindak kejahatan terhadap aset digital pada metaverse dilakukan dengan cara pencurian data oleh peretas, peniruan identitas pengguna metaverse, perusakan pada data pengguna dan penyebaran data yang bersifat pribadi. Selain itu kejahatan pada metaverse dilakukan terhadap Non-Fungible Token yang berkaitan erat dengan kekayaan intelektual pada hak cipta, merek dan desain industri. Perlindungan hukum terhadap aset digital pada metaverse dapat diproses di dunia nyata dengan mengimplementasikan peraturan perundang-undangan yang ada pada hukum positif di Indonesia yaitu dengan menerapkan sanksi pidana terhadap tindakan pelanggaran pada metaverse dengan mengimplementasikan Undang-Undang Nomor 27 Tahun 2022 Tentang Perlindungan Data Pribadi sedangkan untuk pelanggaran atau pencurian pada NFT dapat menerapkan aturan hukum pada Undang-Undang Hak Cipta, Merek dan Indikasi Geografis.
PERLINDUNGAN HUKUM BAGI KONSUMEN ATAS PELANGGARAN HAK INFORMASI (Studi Kasus Produk Vitamin D3 yang Tidak Memiliki Izin Edar BPOM)
Authors:   Fakultas Hukum Universitas Islam Indonesia, Indonesia, Ainiyyah Maya , Wulansari Retno ,   Fakultas Hukum Universitas Islam Indonesia
Published: April 2024

Tingginya permintaan vitamin D3 membuka celah bagi pelaku usaha untuk menjual vitamin D3 yang tidak memiliki izin edar BPOM, sehingga menimbulkan kerugian materil bagi konsumen. Permasalahan yang dibahas adalah bagaimana perlindungan hukum dan tanggung jawab hukum atas hak informasi bagi konsumen produk vitamin D3 yang tidak memiliki izin edar BPOM. Penelitian ini merupakan penelitian hukum normatif dengan cara meneliti bahan pustaka atau data sekunder sebagai bahan dasar untuk diteliti dengan cara mengadakan penelusuran terhadap peraturan dan literatur yang berkaitan dengan permasalahan yang diteliti. Hasil pembahasan yaitu kegiatan usaha tersebut melanggar hak konsumen atas informasi yang benar pada Pasal 4 UUPK, sehingga muncul konsekuensi hukum berupa pemberian ganti kerugian. Konsumen dalam kasus vitamin D3 belum terlindungi, karena kurangnya pengawasan oleh pemerintah terhadap kegiatan usaha terutama pada kegiatan usaha yang dilakukan secara online, sehingga banyak pelaku usaha yang menyalahgunakan jual beli online dengan melakukan perbuatan yang menyimpang. Selain itu, penerapan tanggung jawab berupa ganti kerugian belum berjalan sebagaimana mestinya, hal itu dikarenakan kesadaran dari pelaku usaha untuk bertanggung jawab atas kerugian yang dialami oleh konsumen.
PENGELOLAAN LINGKUNGAN HIDUP DAN PENCEGAHAN BENCANA MELALUI KONSEP ECO-DEVELOPMENT (Studi Kasus Di Kawasan Mangrove Baros Kabupaten Bantul Propinsi Yogyakarta)
Authors: Mumpuni Niken Wahyuning Retno , Wati Krisna Mutiara
Published: April 2024

Kawasan hutan Mangrove Dusun Baros merupakan salah satu pembangunan ekowisata yang telah dikembangkan selama 15 tahun terakhir. Pengembangan hutan mangrove ini merupakan upaya mitigasi bencana dalam rangka mencegah terjadinya bencana pesisir antara lain tsunami, erosi dan abrasi pantai karena gerusan gelombang laut, rob, dan badai atau angin kencang. Seiring berjalannya waktu, pola kehidupan masyarakat sudah cenderung ke arah yang tidak baik yaitu dengan banyak ditemukannya penambangan pasir secara ilegal. Konsep eco-development dirasa peneliti cocok untuk diterapkan di kawasan pesisir tersebut. Hal ini dikarenakan pembangunan yang dilaksanakan dengan konsep ini akan mampu memenuhi kebutuhan masyarakat saat ini dengan tanpa mengurangi kemampuan generasi mendatang untuk memenuhi kebutuhan mereka di masa mendatang. Dalam artian, kegiatan ini merupakan konsep pelestarian lingkungan yang mampu menghasilkan nilai tambah bagi masyarakat dengan tanpa mengurangi jatah hidup untuk generasi anak cucu mendatang.Tujuan dalam penulisan ini adalah meningkatkan kapasitas pengetahuan masyarakat dalam hal kesadaran melestarikan lingkungan dan pencegahan bencana. Sehingga potensi pariwisata yang ada di Kawasan Hutan Mangrove Dusun Baros dapat dikembangkan dengan baik. Pada penelitian ini, metode penelitian yang akan digunakan adalah metode penelitian kualitatif. Pengambilan data dalam penelitian ini dilakukan dengan menyelenggarakan Penyuluhan dan Pendampingan yang dihadiri oleh responden penelitian. Hasil simpulannya masyarakat yang ada di Dusun Baros diketahui Pengembangan Ekowisata Hutan Mangrove Baros memiliki dampak positif bagi masyarakat disekitarnya. Peran KP2B dalam mengembangkan Kawasan Ekowisata Hutan Mangrove dapat menciptakan kesejahteraan dan pengembangan pengelolaan lingkungan yang berkelanjutan dan dapat dimanfaatkan dengan baik sehingga konsep Eco Development dapat dijalankan sesuai dengan regulasi yang ada.
PEMAKNAAN DISPARITAS PERKAWINAN PADA USIA ANAK UNDANG – UNDANG NOMOR 16 TAHUN 2019 DAN UNDANG – UNDANG NOMOR 35 TAHUN 2014
Authors:   Fakultas Hukum Universitas Islam Indonesia, Indonesia, Putri Tania Ariska , Sanjaya Umar Haris ,   Fakultas Hukum Universitas Islam Indonesia, Indonesia
Published: April 2024

Undang-Undang Nomor 16 Tahun 2019 tentang Perkawinan menyebutkan pada Pasal 7 ayat (1) bahwasannya, perkawinan hanya diizinkan apabila pria dan wanita sudah mencapai usia 19 tahun. Selanjutnya, Pasal 7 ayat (2) yaitu apabila terjadinya penyimpangan terhadap ketentuan umur sebagaimana dijelaskan dalam Pasal (1), orang tua pihak pria maupun wanita dapat mengajukan dispensasi perkawinan kepada pengadilan dengan alasan mendesak disertai bukti pendukung yang cukup. Berdasarkan ketentuan Pasal 7 ayat (2) tersebut bertentangan dengan Pasal 26 ayat (1) huruf c Undang-Undang Nomor 35 Tahun 2014 tentang Perlindungan Anak yang menjelaskan mengenai tanggung jawab orang tua untuk mencegah terjadinya perkawinan pada usia anak. Terdapat ketidaksesuaian pada kedua Undang-Undang tersebut, dalam Undang-Undang perlindungan anak orang tua berkewajiban mencegah terjadinya perkawinan pada usia anak sedangkan dalam Pasal 7 ayat (2) Undang-Undang perkawinan justru membuka peluang bagi orang tua untuk dapat menikahkan anaknya yang masih dibawah batas usia diperbolehkannya menikah tanpa melanggar aturan Negara.
PENGELOLAAN SAMPAH BERDIMENSI HUKUM DAN KESADARAN HUKUM MASYARAKAT DI KOTA KENDARI
Authors:   Universitas Halu Oleo, Indonesia, Hasima Rahman , Rosidin Ayib ,   Universitas Halu Oleo, Indonesia, Sumarlin Sumarlin ,   Universitas Halu Oleo, Indonesia, Sakti Abdul ,   Universitas Halu Oleo, Indonesia, Saktiansyah La Ode Ahmad ,   Universitas Halu Oleo, Indonesia
Published: April 2024

Tujuan Penelitian ini adalah untuk mengetahui pengelolaan sampah berbasis kesadaran hukum dan kebijakan pengelolaan sampah yang berdimensi hukum. Penelitian ini menggunakan tipe penelitian yuridis empiris adalah penelitian hukum mengenai pemberlakuan atau implementasi ketentuan hukum normatif secara in action pada setiap peristiwa hukum tertentu yang terjadi dalam masyarakat. Dalam penelitian ini akan dilakukan evaluasi dan analisis secara hukum dan empiris terkait strategi pengelolaan sampah berdimensi hukum dan kesadaran hukum masyarakat Kota Kendari. Menggunakan Teknik pengumpulan data melalui studi lapangan dan studi kepustakaan. Berdasarkan hasil penelitian menunjukan bahwa pengelolaan sampah berdimensi hukum dan kesadaran hukum masyarakat Kota Kendari dengan pendekatan pola reduce, reuse, dan recycle sebagaimana yang dituangkan secara jelas dalam rumusan ketentuan Peraturan Daerah Nomor 4 Tahun 2015 tentang Pengelolaan Sampah yang dapat dilaksanakan dengan cara: 1) Penetapan dan penataan kelembagaan pengelolaan, 2) Pembukaan akses terhadap peran dan fungsi kelembagaan pengelolaan sampah pada setiap tingkatan pengelolaan, 3) Harmonisasi dan koordinasi kelembagaan pengelolaan sampah, 4) Peningkatan pemahaman SDM kelembagaan pada setiap tingkatan pengelolaan sampah, dan 5) Peningkatan kolaborasi dan sharing informasi terkait dengan pengelolaan sampah dengan pola reduce, reuse, dan recycle.
Pancasila as The Foundation of The State in The Perspective of The Democratic State of Law's Ideals
Authors:   Universitas Andalas, Indonesia, Okliyani Windicha , Maharani Septia Riska ,   Universitas Andalas, Indonesia, Ihsan Muhammad Aufal ,   Universitas Andalas, Indonesia, Sari Lusi Puspika ,   Universitas Andalas, Indonesia
Published: April 2024

Pancasila is the foundation and ideology of the Indonesian state that has become the foundation in developing a democratic legal system. Pancasila becomes the basis of the Indonesian legal ideals as a democratic state because it contains values that are in line with the principles of democracy. As the basis of legal ideals, Pancasila has a central role in composing a legal system that guides the direction and principles in carrying out a just, democratic, and law- based governance. The values contained in Pancasila, such as social justice, just and civilized humanity, democracy, and popular sovereignty, become the basis for the formation of laws and public policies. In practice, Pancasila serves as a source of law in the process of making public policies and stipulating laws in Indonesia. Pancasila values also serve as a reference in law enforcement, where judges' decisions and public policies must be in line with Pancasila values. Pancasila also has an important role in maintaining the unity and unity of the Indonesian nation. Pancasila values, such as Bhinneka Tunggal Ika, become the basis for building a strong and robust unity in Indonesian society, so that a just, democratic, and sovereign state can be realized, thus creating a prosperous and harmonious society.
Conceptualizing White-Ability Saviorism: A Necessary Reckoning With Ableism in Urban Teacher Education
Authors: Siuty Molly Baustien , Beneke Maggie R. , Handy Tamara
Published: April 2024

White saviorism is a well-documented phenomenon in the education literature. Particularly, researchers have made connections between white saviorism and teacher preparation for urban contexts serving Students of Color negatively impacted by legacies of systemic racism. Scholars are increasingly taking an intersectional lens to understand the ways in which racism and ableism intersect, yet much of the literature on white saviorism does not critically examine the role of ableism. In this meta-ethnography, we review extant qualitative research on urban teacher preparation in an effort to extend the analysis to include a robust examination of ableism and deepen our understandings of white supremacy in these spaces. To this end, we conceptualize white-ability saviorism as a more comprehensive and precise way to understand the dynamics at play in urban teacher preparation that contribute to white supremacy and perpetuate educational inequities for urban Communities of Color.
Progress in Cervical Cancer Biomarkers
Authors: Ma Huangrong , Wang Yifu , Cai Miaoying , Yang Li , Xu Zhiyuan
Published: April 2024

Objective: Cervical cancer (CC) tops the list as the most prevalent malignant tumors of the female reproductive system and is one of the leading causes of cancer-related deaths in women worldwide. To improve the prognosis of CC, research has consistently focus on understanding innovative approaches. Biomarker-guided precision medicine is an important direction to improve prognosis. In this paper, we aim to deepen our understanding of CC biomarkers and accelerate their translation into clinical practice. Mechanism: Literature studies on biomarkers for CC were screened from 23 May 2019 to 23 May 2023. A comprehensive search was performed in NIH/NCBI/PubMed databases. Findings in Brief: There are numerous biomarkers that have a significant role in the diagnosis, prognosis, and treatment of CC. They can influence various processes such as tumour proliferation, invasion, infiltration, and apoptosis. They are also related closely to the sensitivity and resistance of radiotherapy and chemotherapy. Conclusions: To date, multiple CC biomarkers have been identified. Few biomarkers have been successfully applied in clinical practice due to the lack of validation in large-scale clinical studies. Therefore, further clinical studies are necessary to realize the great potential in the clinic.
Effects of Sucrose, Trehalose, and Fructose on Whole Ovarian Cryopreservation in a Rat Model
Authors: Xie Lingyun , Ding Yan , Xu Ping , Hua Keqin , Zhang Xuyin
Published: April 2024

Background: Recently, the utilization of sugar as a cryoprotectant has garnered significant attention. Sucrose and trehalose, as non-permeable cryoprotectants, can effectively regulate the osmotic pressure inside and outside cells while maintaining cell membrane stability during cryopreservation. Furthermore, it has been observed that monosaccharides sugars, particularly fructose, exhibit superior efficacy in preserving the quality of frozen substances as compared to disaccharides and trisaccharides sugars. Nevertheless, there is currently limited research assessing the cryopreservation effects of sucrose, trehalose, and fructose. The objective of this experiment is to identify the best cryoprotectant between sucrose, trehalose, and fructose for intact rat ovaries. Methods: Intact ovaries with blood vessels were obtained from 20 adult Lewis female rats and divided accordingly into four groups: control (non-vitrified), sucrose, fructose, and trehalose. The ovarian samples were subjected to a stepped cryoprotectant exposure and subsequently follicular histological analysis using light and electron microscopy. Ovarian cell apoptosis was evaluated by BCL2-Associated X (BAX) immunohistochemistry and Terminal Deoxynucleotidyl Transferase-Mediated Deoxyuridine Triphosphate nick End-Labeling (TUNEL) analyses. Results: The sucrose and the trehalose groups preserved the ovarian histological structure better than the fructose group. Additionally, there was no statistical difference in the total follicle number between the sucrose and trehalose groups, but the percentage of apoptotic cells in the trehalose group was significantly lower than that of the sucrose group (p < 0.01). Conclusions: Sucrose and trehalose perfusion protocols preserved the ovarian histology. However, the least apoptotic changes were observed in the trehalose group. The study suggested that trehalose would be a well-applied cryoprotectant in the cryopreservation of intact rat ovaries.
FOXA1/UBE2T Inhibits CD8+T Cell Activity by Inducing Mediates Glycolysis in Lung Adenocarcinoma
Authors: Pu Jiangtao , Zhang Dengguo , Wang Biao , Zhu Peiquan , Yang Wenxing , Wang Kaiqiang , Yang Ze , Song Qi
Published: April 2024

Background: Immune escape is a key factor influencing survival rate of lung adenocarcinoma (LUAD) patients, but molecular mechanism of ubiquitin binding enzyme E2T (UBE2T) affecting immune escape of LUAD remains unclear. The objective was to probe role of UBE2T in LUAD. Methods: Bioinformatics means were adopted for analyzing UBE2T and forkhead box A1 (FOXA1) expression in LUAD tissues, the gene binding sites, the pathway UBE2T regulates, and the correlation between UBE2T and glycolysis genes. Dual luciferase and chromatin immunoprecipitation (ChIP) assays were conducted for validating the binding relationship between the two genes. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) and western blot were employed to evaluate UBE2T, FOXA1, and programmed death ligand 1 (PD-L1) levels in cancer cells. MTT assay was conducted for detecting cell viability. Cytotoxicity assay detected CD8+T cell toxicity. Cytokine expression was assayed by enzyme linked immunosorbent assay (ELISA). Extracellular acidification rate (ECAR) and oxygen consumption rate (OCR) were assayed by extracellular flow analyzer. Glycolytic gene expression was analyzed by qRT-PCR, and glycolysis-related indicators were detected by ELISA. Immunohistochemistry (IHC) detected CD8+T cell infiltration in tumor tissues. Results: FOXA1 and UBE2T were up-regulated in LUAD, and a binding site existed between UBE2T and FOXA1. Overexpressing UBE2T could increase PD-L1 expression and inhibit toxicity of CD8+T cells to LUAD cells. Overexpressing UBE2T repressed CD8+T cell activity in LUAD by activating the glycolysis pathway, and the addition of glycolysis inhibitor 2-deoxy-d-glucose (2-DG) reversed the above results. Mechanistically, FOXA1 promoted the immune escape of LUAD by up-regulating UBE2T and thus mediating glycolysis. In vivo experiments revealed that UBE2T knockdown hindered tumor growth, inhibited PD-L1 expression, and facilitated CD8+T cell infiltration. Conclusion: FOXA1 up-regulated the expression of UBE2T, which activated glycolysis, and thus inhibited activity of CD8+T cells, causing immune escape of LUAD.
Mechanisms of Vein of Marshall-Related Tachyarrhythmias and the Impact of Ethanol Infusion
Authors: Takigawa Masateru , Martin Claire , Jaïs Pierre
Published: April 2024

The Ligament of Marshall (LOM) is a remnant of the embryonic sinus venosus and the left cardinal vein, containing a combination of fat, fibrous tissue, blood vessels, muscle bundles, nerve fibers, and ganglia. Various muscular connections exist between the LOM and the left atrium (LA) and the coronary sinus (CS). The LOM is richly innervated by autonomic nerves, with ganglion cells distributed around it. The unique characteristics of the LOM are responsible for generating focal electrical activities and enable it to serve as a substrate for micro- and macro-reentrant circuits. This, in turn, leads to the initiation and perpetuation of atrial fibrillation (AF) and atrial tachycardia (AT). Endocardial ablation in this region does not consistently succeed due to anatomical constraints within the left lateral LA, including the presence of a thicker and longer mitral isthmus (MI), anatomical variations between the MI and epicardial structures such as the CS and vein of Marshall (VOM) and circumflex artery, and the presence of fibrofatty tissue insulating the LOM. Furthermore, epicardial ablation is challenging for inexperienced institutions because of its invasive nature. Ethanol infusion into the VOM (EI-VOM) represents an effective and safe approach that can be employed in conjunction with radiofrequency ablation to eliminate this arrhythmogenic structure.
Remote Ischemic Preconditioning Before Drug-Coated Balloon Implantation can Improve the Long-Term Prognosis of Patients with CAD
Authors: Zhao Zhenzhou , Yu Haosen , Nie Ming , Li Xuejie , Li Muwei
Published: April 2024

Background: Drug-coated balloons (DCBs) have become increasingly vital to percutaneous coronary intervention, offering many advantages. However, a significant challenge is that many patients are intolerant to the myocardial ischemia caused by DCB dilation. Remote ischemic preconditioning (RIPC) is known to enhance heart’s tolerance to ischemia and hypoxia. This study investigated whether preoperative RIPC could extend the tolerated DCB inflation time and improve the long-term prognosis of patients with coronary artery disease (CAD). Methods: A total of 653 patients with CAD were recruited and randomized into a RIPC group (n = 323) and a control (n = 330) group. The RIPC group underwent RIPC on the left upper limb twice daily, starting three days before the DCB implantation. The patients were followed up for one year after the operation, and 197 patients returned for coronary angiography (CAG) examination where the quantitative flow ratio (QFR) of the target vessels was measured. The primary endpoint of the study was the incidence of target lesion failure (TLF), which included target lesion revascularization (TLR), target vessel myocardial infarction, and cardiac death. The secondary endpoint was the rate of QFR loss in the target vessels. Results: The findings revealed a significantly lower incidence of TLR in the RIPC group compared to the control group. Additionally, at the one-year follow-up, the rate of QFR loss in target vessels was lower in the RIPC group than in the control group. Conclusions: The preoperative application of RIPC effectively extended the duration patients could tolerate DCB inflation. Furthermore, this approach positively impacted the long-term prognosis of CAD patients undergoing DCB treatment. Clinical Trial Registration Information: NCT04766749.
Exercise Prescription in Individuals with Prehypertension and Hypertension: Systematic Review and Meta-Analysis
Authors: Xi Yang , Liu Xiaoyun , Chen Yuanyuan
Published: April 2024

Background: The prevalence of prehypertension and hypertension has been increasing over the years, and is closely related to cardiovascular and cerebrovascular diseases. Exercise is an effective method of lifestyle intervention, and it aims to lower blood pressure and control other risks. Studies have shown that different modes of exercise have varying effects on blood pressure, and individuals with prehypertension or hypertension need to carry out this intervention by using personalized modes of exercise. Methods: We conducted a systematic review and meta-analysis to evaluate the effects of different modes of exercise regimens on systolic blood pressure, diastolic blood pressure and heart rate in individuals with high-normal blood pressure and hypertension. We included 27 trials, and 2731 individuals were under 8 exercise regimens. Stata12.0 statistical software was used for statistical analysis. Results: Heat pools significantly reduced systolic blood pressure (SBP) by 15.62 mmHg (95% confidence interval [CI]: –23.83, –7.41), and cycling reduced SBP by 14.76 mmHg (–17.04, –12.48). Two to three types of aerobic exercise performed at the same time also significantly reduced diastolic blood pressure (DBP) by 5.61 mmHg (–7.71, –3.52), and isometric handgrip training exercise reduced DBP by 5.57 mmHg (–7.48, –3.66). Cycling also significantly reduced heart rate (HR) by 9.57 beats/minute (–11.25, –7.90). Conclusions: The existing literature suggests that different types of exercise can effectively reduce the levels of SBP, DBP and HR in individuals with prehypertension or hypertension.
Evaluation of Six eGFR Equations in Predicting Acute Kidney Injury in Patients after Off-Pump Coronary Artery Bypass Grafting: A Case Control Study
Authors: Tang Jiwen , Zhang Congcong , Hu Weiwei , Qu Weili
Published: April 2024

Background: There are six widely used equations to calculate the estimated glomerular filtration rate (eGFR) of patients. We aimed to assess the predictive power of preoperative eGFR calculated by these equations for the occurrence of postoperative acute kidney injury (AKI). Methods: Patients who underwent isolated coronary surgery from January 2016 to January 2021 were continuously enrolled. Serum creatinine and cystatin C used to calculate eGFR were both measured within 1 week before surgery. The eGFR was calculated using six equations: Cockcroft Gault (CG) equation, Chinese abbreviated modification of diet in renal disease (MDRD) equation, chronic kidney disease-epidemiology (CKD-EPI) equation, and full age spectrum (FAS) equation. Postoperative AKI was diagnosed by Kidney Disease Improving Global Outcomes criteria (KDIGO) (① urine volume <0.5 mL/kg/h for 6 h; ② an increase in serum creatinine by ≥26.5 µmol/L within 48 h; ③ an increase in serum creatinine to ≥1.5 times baseline levels, which is known or presumed to have occurred within the prior 7 days), and the occurrence of AKI within 7 days after surgery was followed. Results: A total of 1428 patients were included, of which 319 patients (25.5%) developed postoperative AKI. After adjustment, all eGFRs (CG OR = 0.983, MDRD OR = 0.983, CKD-EPIcrea OR = 0.97, CKD-EPIcys OR = 0.955, FAScrea OR = 0.978, FAScys OR = 0. 941, all p < 0.001) were significantly associated with AKI. The area under the receiver operating characteristic curve (AUC) was 0.621 for CG, 0.614 for MDRD, 0.643 for CKD-EPIcrea, 0.739 for CKD-EPIcys, 0.643 for FAScrea, 0.744 for FAScys, respectively. There was no difference in predictive power between FAScys and CKD-EPIcys (p = 0.33, DeLong’s test). Conclusions: Preoperative eGFR calculated by FAScys and CKD-EPIcys equations have better performance in predicting AKI after off-pump coronary artery bypass grafting than other equations.