bluuebunny/crossref_metadata_2025 huggingface dataset:
Political Pathways and Performance of Women Opposition Leaders in Indonesia and South Korea
Authors: Choi Nankyung
Published: January 2023

While some world regions have seen women opposition leaders with no ties to political families rise to national leadership, in East Asia, women opposition leaders who ascend to national executive positions have been largely limited to the wives, daughters, or sisters of prominent male politicians. Locally, however, there have been some broadening and diversification of women who seek and win executive office through oppositional politics. Given the small number of women opposition leaders who have gained leadership positions in the government, this article develops an interpretive study of the relationship between becoming “critical actors” and doing “critical acts” as women opposition leaders. Using four illustrative cases of women who have pursued executive power through oppositional politics, this article questions whether and how the variation in women’s pathways affects their exercise of power in Indonesia and South Korea, two young though consolidating democracies in East Asia. Drawing on the biographies and policies of two presidents (Megawati Soekarnoputri and Park Geun-hye) and two mayors (Tri Rismaharini and Kim Soo-young) it shows that local women opposition leaders use their executive leadership to initiate and implement public policies, unlike their national counterparts whose pathways and performance are intertwined with family background. By doing so, the article sheds light on the complex nexus between political pathways and performance of women opposition leaders.
Supervision as an Element of Transmitting of the Reflective–Activity Approach to Assistance in Overcoming Learning Difficulties
Authors: Gordon M.M. , Gordon M.M. , Nikolaevskaia I.A.
Published: January 2023

The problem of transmitting of technologies of psychological and pedagogical counseling of students on overcoming learning difficulties by means of a reflective–activity approach (RAA) is posed. The limited possibilities of teaching student counselors on the basis of learning situations are discussed. The method of transmitting the principles and technologies of counselling by means of RAA through the organization of supervisory and intervisor groups is considered. A reflective analysis of two options for constructing supervisory support for student counsellors mastering RAA is given. When comparing them, conclusions are drawn about the general logical sequence of passing through the key moments of mastering the RAA in the course of supervision, as well as about the main feature of the supervisory process. In the course of supervision, helping student counsellors to overcome their difficulties in mastering the approach is built on the same principles of RAA as their assistance to school students in overcoming learning difficulties. Thus, students get a double experience of helping with RAA, available for reflection: the experience of providing such assistance, and the experience of receiving such assistance.
Teaching Chess on the Basis of the Refletiive-Activity Approach in the Context of the Problem of Gaining Legal Capacity: a Case from Practice
Authors: Sidorenko A.A.
Published: January 2023

The relevance of the study is due to the reform of social protection and the need to find resources to restore legal capacity to disabled people living in residential facility for people with mental disabilities (PNI). The study was conducted as part of a comprehensive rehabilitation of those living in PNI, aimed at restoring their capacity to work. The purpose of the study is to test the possibility of using chess for the cognitive and personal development of those living in PNI, as an important condition for improving their mental health. The article provides an analysis of the case of Anton, aged 30 (name and biographical data have been changed), who was legally recognized as incompetent and has been living in PNI for three years. Classes according to the technology "Chess for General Development" were conducted during the year by psychologists–consultants working by means of a reflective–activity approach in order to promote the acquisition of legal capacity. Specific events during this year that contributed to Anton's cognitive and personal development against the backdrop of constant progress in chess are analyzed. It is shown how these events and the growing self–confidence led to a gradual change in Anton's social status (he gets a job, leaves the boarding school, returns to his family, stops taking medications in agreement with the doctors). It also shows the stability and positive dynamics of these positive changes over the next two years. Based on the method of situational–vector analysis, it is shown how, in the course of chess lessons with the support of consultants, resources were increased in the form of strengthening the subjective position, developing reflection and increasing self–efficacy, which contributed to the positive dynamics of development towards gaining legal capacity.
Interview with V.V. Nikolaeva: All of Us Used to Follow the Cultural-Historical Tradition
Authors: Zaretsky V.K. , Kholmogorova A.B. , Pechnikova L.S.
Published: January 2023

We present an interview with Valentina V. Nikolaeva, Doctor of Psychology, Professor of the Department of Neuro- and Pathopsychology, Lomonosov Moscow State University (Moscow, Russia).
Diabetic coma in the mortality of patients with diabetes mellitus
Authors: Akimov Pavel A. , Barinov Evgeny K. , Terekhina Natalya A.
Published: January 2023

BACKGROUND: Statistics on the causes of death of patients with diabetes mellitus do not correspond to real indicators because of the insufficient level of diagnosis at the post-mortem stage of research in most regions of the country.
AIM: This study aimed to statistically analyze the mortality of patients with diabetes as a result of diabetic coma in the period from 2017 to 2020.
MATERIALS AND METHODS: The study examined blood and vitreous body of the eyes from 4444 patients with diabetes mellitus. The levels of glycohemoglobin in the blood and glucose, lactate, and acetoacetate in the vitreous body of the eyes were determined. The diagnosis of diabetic coma was made taking into account previously developed criteria.
RESULTS: A total of 692 (15.6%) patients with diabetes mellitus died of diabetic coma. Diabetic coma-related deaths occupy a much larger percentage of cases than is available in statistical data because of the insufficient implementation of laboratory tests at the post-mortem stage of diagnosis and restricted coding of the cause of diabetic coma-related death of patients with diabetes mellitus. Methods for diagnosing diabetic comas are easy to perform, guarantee high accuracy and reliability of results, and are available for any specialized laboratory.
CONCLUSION: The most common precomatous state (the beginning of the development of hyperosmolar non-ketoacidotic coma), which in combination with coma itself, leads to the highest rates of diabetic coma-related death. In recent years, diabetic coma-related death tended to reduce.
Model of small-focal ischemic cerebral infarction as a basis for the development of new methods of stroke therapy
Authors: Markosyan Vage A. , Izmailov Andrei A. , Sokolov Mikhail E. , Valiullin Viktor V. , Safiullov Zufar Z.
Published: January 2023

Background. Among the existing experimental models of cerebral stroke in large animals, there is no possibility to create a focal brain infarction of limited volume, which would provide an opportunity to evaluate both the endogenous potential of neuroregeneration and to establish the effectiveness of new drugs on postischemic brain remodeling.
Aim. Development of a method for modeling small-focal ischemic infarction of the cerebral cortex in a mini-pig.
Material and methods. The study used mature female mini-pigs of the Vietnamese fold-bellied breed. Two-level occlusion of the great vessels was performed by ligation of the right common carotid artery and subsequent cauterization of the distal branches of the middle cerebral artery. In the postoperative period, the survival rate of animals and neurological deficit were assessed. On the 7th day, the animals were taken out of the experiment, the brain was isolated from the cranial box. Macroscopic and microscopic examinations included analysis of the localization and area of cerebral infarction, as well as morphological changes in the infarcted and peri-infarcted areas of the cerebral cortex.
Results. With a 100% survival rate of experimental animals on the 3rd day after the operation, a neurological examination revealed violations of skin sensitivity and muscle tone in the hind and fore limbs, which partially recovered a week after the onset of ischemic stroke. Macroscopic examination of the brain on the 7th day after the operation visually revealed a small-focal ischemic cerebral infarction in the parietal lobe of the left hemisphere. Histological analysis of the cerebral cortex revealed a wedge-shaped necrotic focus of ischemic injury. In the peri-infarction region of the brain, reactive tissue changes with preserved nerve cells, mostly without visible damage, were found.
Conclusion. The developed two-level method of stroke modeling in a mini pig induces ischemic cerebral infarction of limited volume in the parietal lobe; non-critical histological changes in the peri-infarct area and a slight neurological deficit suggest the possibility of using this model to develop new methods of stroke therapy.
Changing Approaches to Criminal Liability for Fraud in the Field of Entrepreneurship in the Context of New Economic Challenges
Authors: Merkushina Svetlana I.
Published: January 2023

In the context of new economic challenges, this article discusses the prospects of reforming criminal liability for fraud in the field of entrepreneurial activity (Part 57 of Article 159 of the Criminal Code of the Russian Federation).
Improvement and Transformation of Companies’ Tax Management Practices
Authors: Seliutina Tatiana S.
Published: January 2023

An important process in companys tax management is the formation and optimisation of an accounting policy for tax purposes that can ensure an increase in the mass of tax benefits for an economic entity - a taxpayer. The paper substantiates the relevance and necessity of tax management. The purpose of tax management is to increase the economic efficiency of an economic entity and to ensure the entity is economically and legally secure. Tax management also functions as a tool for the entity's success hence accurate and complete information and methodological support are needed for its execution. The author considers the lower level of tax management the level of taxpayer organisations whose main task is to maintain and increase their financial well-being. The tax legislation of the Russian Federation uses the term accounting policy for tax purposes. The policy acts as a documentary confirmation of the methods chosen by a company to optimise tax payments within the legal framework. The author views the features of the process and procedure for the formation of an accounting tax policy, and in the context of the identified features provides directions for improving the accounting policy document. The gradual expansion of understanding of the meaning and functionality of tax management for a company is also pointed out. The traditional understanding was assumed to be the basis of tax management activity, the search for gaps in tax legislation and their use to the benefit of the company at the operational-tactical level. It is now believed that tax management should be strategic, including cooperation with government agencies in order to change the legal system and to create new exemptions for specific industries and types of enterprises.
Bringing to Justice in the Criminal Procedure: Theoretical Aspects
Authors: Pechegin Denis  A. , Beskhlebnyi Sergey N.
Published: January 2023

Bringing to trial as one of the key objectives of the Russian criminal justice system is characterised by sufficient dynamism of development. The procedure of criminal proceedings has been subjected to repeated changes and adjustments. Nevertheless, the essence of bringing to trial remained unchanged across the periods, namely to initiate legal proceedings in the case of the accused person. This interpretation was formed during the genesis of the institution of trial and settlement doctrine. Despite the fact that the modern system of criminal justice is at a stage of active improvement, trials remains one of the unresolved issues. The article provides a short historical analysis of the formation of trial institutions in Russia, which, taking into account theoretical developments, makes it possible to clarify the essence of trial and consider the directions of development at the present stage. Additionally, the place of the institution of trial in the system of the current model of international criminal proceedings is revealed.
Kajian Serat dan Komponen Aktif Beras Analog dari Rumput Laut Gracilaria sp.
Authors: Purwaningsih Sri
Published: January 2023

Indonesia merupakan negara tertinggi pengekspor rumput laut Gracilaria sp. dan rumput laut ini mengandung serat pangan yang tinggi (64,74%), mempunyai aktivitas antioksidan kuat. Tujuan penelitian adalah menentukan formula terbaik berdasarkan kadar serat, fenol, tanin, dan flavonoid dari beras analog dari Gracilaria sp. Penentuan beras analog dari rumput laut Gracilaria sp. terbaik menggunakan Rancangan Acak Lengkap (RAL) dengan tiga ulangan, bila hasil uji menunjukkan pengaruh nyata dilanjutkan dengan uji lanjut Duncan pada taraf kepercayaan 95%. Konsentrasi perlakuan yaitu penambahan tepung Gracilaria sp. 0, 10, 13, dan 16%. Hasil analisis beras analog dari rumput laut Gracilaria sp. menurut Codex Alimentarius Commission termasuk makanan sumber serat tinggi, dengan kisaran 6,09-10,77%, mengandung komponen bioaktif (alkaloid, fenol, tanin, dan flavonoid). Kandungan fenol, tanin, dan flavonoid berturut-turut berkisar 160,32-192,89 mg/kg; 0,14-0,24%; 4,02-5,18 mg QE/g. Formulasi beras analog dari Gracilaria sp. terbaik berdasarkan kadar serat, fenol, tanin, flavonoid pada konsentrasi 13%.
Aktivitas Antioksidan dan Stabilitas Fisik Sediaan Body Scrub Bubur Rumput Laut Turbinaria decurrens dan Kencur (Kaempferia galanga)
Authors: Yanuarti Rini , Septiana Dwi Citra , Nurfitriyana Nurfitriyana , Pratama Ginanjar , Haryati Sakinah , Kurniawan Itok Dwi , Putri Dwi Kurnia
Published: January 2023

Rumput laut Turbinaria decurrens diproduksi masih dalam bentuk kering dan bentuk intermediet. Salah satu cara untuk meningkatkan pengembangannya yaitu diolah menjadi sediaan kosmetik. Selain rumput laut, bahan alam yang dapat digunakan untuk sediaan kosmetik lainnya yaitu kencur (Kaempferia galanga). Tujuan penelitian ini adalah menentukan kombinasi bubur rumput laut T. decurrens dan kencur terbaik sebagai sediaan body scrub berdasarkan hasil aktivitas antioksidan serta stabilitas fisiknya. Penelitian ini dilakukan dengan melihat perbedaan konsentrasi rumput laut T. decurrens dan kencur dengan perbandingan 1:1 (Krim RK1), 1:2 (Krim RK2), dan 2:1 (Krim RK3) dan tanpa penambahan rumput laut dan kencur (Krim RK0). Analisis yang dilakukan mencakup fitokimia, antioksidan, stabilitas sediaan krim dan tipe emulsi. Bubur rumput laut T. decurrens mengandung senyawa alkaloid, flavonoid, tanin dan fenol hidrokuinon, sedangkan serbuk kencur mengandung senyawa alkaloid, dan flavonoid. Bubur rumput laut T. decurrens memiliki aktivitas antioksidan sedang (IC50 119,36 µg/mL), sedangkan serbuk kencur memiliki aktivitas antioksidan sangat lemah (IC50 569,66 µg/mL). Hasil tersebut berbeda dengan aktivitas antioksidan pada sediaan krim body scrub yang mendapatkan aktivitas antioksidan sangat kuat. Nilai IC50 pada formulasi krim RK1, RK2 dan RK3 berturut-turut adalah 1,60±0,12 µg/mL; 1,24±0,15 µg/mL dan 2,49±0,05 µg/mL. Hasil stabilitas sediaan menunjukan krim body scrub memiliki pH seimbang (6,3–7,33) dan aman untuk kulit, Berdasarkan hasil pengujian didapatkan formulasi krim RK2 yang merupakan formulasi sediaan krim terbaik, dilihat dari hasil antioksidan dan stabilitas fisik sediaan krim
Isolasi Asam Lemak dan Kadar Pigmen Rumput Laut Cokelat Sargassum crassifolium sebagai Sumber Antioksidan Alami
Authors: Sanger Grace , Dotulong Verly , Damongilala Lena Jeane
Published: January 2023

Sargassum adalah produk hasil laut, sumber senyawa bioaktif yang memiliki  aktivitas biologi, terutama sebagai antioksidan dan antikanker.  Ekstrak maupun isolat  Sargassum telah  dimanfaatkan sebagai produk kesehatan pada berbagai industri seperti, pangan, obat-batan dan kosmetik.  Asam lemak (E)-11-octyloxacyclododec-10-en-2-one,  telah diisolasi dari fraksi etil asetat rumput laut cokelat S. crassifolium menunjukkan mempunyai aktivitas antioksidan. Tujuan penelitian yaitu mengisolasi senyawa asam lemak, mengukur kadar pigmen dan aktivitas antioksidan S. crassifolium.  Metoda pemurnian dan isolasi sebagai berikut: Sargassum diekstraksi dengan metanol menggunakan kolom kromatografi (KK), kemudian dipartisi dengan heksana, etil asetat, setelah itu dibilas dengan metanol.  Fraksi etil asetat kemudian dimurnikan dan diisolasi menggunakan KK dan Kromatografi Lapis Tipis (KLT) dgunakan untuk memonitor dan mengobservasi  kehadiran senyawa bioaktif.  Isolat senyawa murni fraksi etil asetat S. crassifolium (FEtSar) dikarakterisasi menggunakan NMR, FTIR dan ESMS dan dibandingkan dengan literatur terkini. Ekstrak, fraksi dan  isolat murni  diuji kadar pigmen (carotenoid dan fucoxanthin) dan aktivitas  antioksidant 2,2-diphenyl-1-picrylhydrazyl (DPPH) . Hasil studi menunjukkan bahwa ekstrak, fraksi dan isolat murni (E)-11-octyloxacyclododec-10-en-2-one (FEtSar)   Sargassum crassifolium mengandung senyawa  antioksidan. Aktivitas antioksidan tertinggi adalah fraksi heksana (IC50 2,657±0,338 mg mL-1) dengan Kadar fukosantin dan karotenoid masing-masing 33,04±3,348 dan 24,911±2,4231 µg g-1.  S. crassifolium potensiall dimanfaatkan sebagai sumber antioxidant alami  dan dimasa depan dapat dimanfaatkan sebagai produk kesehatan.
Kapasitas Antioksidan dan Sifat Fisikokimia Hidrolisat Kolagen dari Kulit Ikan Tuna Sirip Kuning dengan Metode Ultrasound Assisted Enzymatic Reaction
Authors: Wirayudha Raden Hilman , Herawati Dian , Kusnandar Feri , Nurhayati Tati
Published: January 2023

Hidrolisat kolagen larut pepsin dari kulit ikan tuna sirip kuning merupakan produk turunan yang diperoleh dari hasil hidrolisis kolagen larut pepsin menggunakan kombinasi proses ekstraksi enzimatis dengan enzim protease (Alkalase®) dan ekstraksi fisik dengan metode ultrasonikasi. Tujuan dari penelitian ini yaitu memproduksi kolagen larut pepsin dari bahan baku kulit ikan tuna sirip kuning, mengevaluasi pengaruh waktu sonikasi dan konsentrasi enzim alkalase untuk mendapatkan produk hidrolisat terbaik, serta membandingkan karakteristik fisikokimia fungsional dan antioksidan dari kolagen larut pepsin dengan hidrolisatnya. Kolagen larut pepsin yang dihasilkan dibuat dengan ekstraksi secara asam menggunakan asam asetat dan juga enzim pepsin dengan konsentrasi 750 U/mg. Analisis data untuk penentuan kondisi hidrolisis optimum menggunakan Rancangan Acak Lengkap Faktorial dengan dua faktor. Hidrolisat kolagen dengan nilai derajat hidrolisis, serta aktivitas penghambatan antioksidan metode DPPH dan ABTS tertinggi diperoleh pada perlakuan penambahan enzim Alkalase® sebanyak 2:20 (enzim/mg protein) dengan waktu hidrolisis selama 2 jam menggunakan metode ultrasonikasi. Karakeristik fisikokimia dan sifat antioksidan dari produk hidrolisat kolagen jauh lebih baik jika dibandingkan dengan bentuk utuh kolagen, di antaranya yaitu bobot molekul yang lebih rendah hingga mencapai 5 kDa, asam amino sebesar 56,93%, kelarutan bahan dalam air sebesar 99,54%, dan kapasitas penghambatan antioksidan yang lebih tinggi pada penghambatan DPPH dengan IC50 sebesar 77,2 mg/L dan ABTS IC50 sebesar 40,72 mg/L.
Bitki Uçucu Yağların Gri Küf Hastalığı Etmeni Botrytis cinerea’nın Misel Gelişimi, Konidi Çimlenmesi ve Hif Morfolojisi Üzerine Antifungal Etkileri
Authors: KÖSE Fatih , SOYLU Emine Mine
Published: January 2023

Gri küf hastalığına neden olan Botrytis cinerea aralarında turunçgil meyvelerininde bulunduğu oldukça geniş konukçu dizisine sahip fungal bir hastalık etmenidir. Bu çalışmada farklı kekik türleri (Origanum onites L., Origanum syriacum Holm., Thymbra spicata L.) ve rezene (Foeniculum vulgare Mill.) bitkilerinden elde edilen uçucu yağların Botrytis cinerea’nın misel gelişimi, spor çimlenmesi ve hiflerinin morfolojik yapısı üzerine buhar fazında antifungal etkinlikleri in vitro koşullarda araştırılmıştır. Uçucu yağlar arasında en yüksek antifungal etkinlik (% 100 engelleme) O. onites ve O. syriacum uçucu yağlarının 10 µg ml-1 dozunda tespit edilmiş olup, bu uygulamaları 40 µg ml-1 dozunda T. spicata ile nispeten daha yüksek dozda (120 µg ml-1) kullanılan F. vulgare uçucu yağları takip etmiştir. Uçucu yağların misel gelişimini tamamen engelleyen dozlardaki etkinliğinin fungisidal özellikte olduğu belirlenmiştir. Test edilen uçucu yağların tamamı 10 µg ml-1 dozda fungus konidilerin çimlenmesini tamamen engellemiştir. Yapılan taramalı ve ışık mikroskop çalışmalarında uçucu yağların minimum engelleme dozlarında fungus misel ve konidileri üzerinde vesikülleşme, sitoplazmalarında pıhtılaşma, hiflerde erime gibi ciddi bozulmalara neden olduğu gözlenmiştir. Mikroskop gözlem sonuçları uçucu yağlar tarafından gösterilen antifungal etkinliğin fungus misel ve konidilerinde neden olunan morfolojik bozulmalardan kaynaklandığını göstermiştir. Elde edilen sonuçlar özellikle kekik türlerine ait uçucu yağların depolanmış ürünlerde sorun olan fungal hastalıklarla mücadelede kimyasallara alternatif çevre dostu biyofungisit olarak kullanılabilme potansiyeline sahip olduğunu göstermiştir.
INVESTIGATION OF THE EFFECTS OF GEOTHERMAL AND MINERAL WATER ON BARLEY (Hordeum vulgare L.) AND WHEAT (Triticum aestivum L.)
Authors: KARATEPE Vasfi , ELVEREN Müjgan , OSMA Etem
Published: January 2023

In the present study, the usability of geothermal and mineral water in agricultural lands was investigated. Geothermal water, mineral water, and tap water with two wheat varieties and one barley variety were used, and six different water groups were formed with geothermal, mineral, and tap water by mixing them at a ratio of 50%. Field soil mixed with 750 g of animal manure was prepared in the growing containers, and then, 6 g of the wheat varieties and 5 g of the barley variety were planted in them. The germinated wheat and barley were irrigated periodically according to their water needs. Barley and wheat were harvested after 15 days. Chlorophyll size, electrolyte leakage, weight, and mineral element concentrations were determined in the harvested crops. The mineral element concentrations of the samples were analyzed in ICP-AES. Additionally, geothermal, mineral and normal water were applied to the soil for three months, and the change between the resulting soil and the starting soil was determined. The collected data were analyzed in the SPSS 22 Statistical Package Program.
Las generaciones de los Derechos Humanos : libertad, igualdad, fraternidad
Authors:   Universidad Libre, Rey Cantor Ernesto
Published: January 2023

El distinguido colega y amigo de vieja data, Ernesto Rey Cantor, me ha solicitado que escriba algunas palabras introductorias a la nueva edición del libro publicado, junto a sus hijas Giovanna Alejandra y Ángela Margarita Rey Anaya, denominado Las Generaciones de los Derechos Humanos. Con mucho gusto acepté el encargo por dos razones: primero, porque a un amigo querido no se le puede dar una respuesta negativa, y en segundo término, porque este tema constituye una de mis debilidades jurídicas. El libro es omnicomprensivo de la materia tratada, lo cual se hace con claridad y precisión, elementos que son determinantes para que la lectura de cualquier libro resulte amena. El texto tiene la virtud de que no se pierde en disquisiciones inútiles, y va directamente al grano al analizar los diferentes aspectos de la materia tratada. El texto parte de una premisa jurídica fundamental, y que compartimos plenamente: considerar el principio de la dignidad humana como fundamento de la libertad, igualdad y fraternidad, que se infieren de la Biblia, bajo la impronta del cristianismo, que después serán adoptados por la Revolución Francesa. Consideran los autores que al crearse al hombre por Dios –y a su semejanza– nació una criatura con fuerza, sabiduría y belleza, porque a imagen de Dios fue creada; es el único ser en el que trasciende la dignidad divina dotado de razón y conciencia; por tanto, la dignidad es inherente a la naturaleza del ser humano irradiada por la luz divina del creador. Es por ello que el ser humano es la criatura más bella del universo, dotado de sabiduría y fuerza espirituales. Aunque difiero del origen divino de la dignidad, sí estoy completamente de acuerdo en que ella es consustancial con el ser humano, es decir que todos los hombres, por el hecho de ser tales, nacemos con una dignidad que nadie nos puede arrebatar. La dignidad es parte integrante de nuestra esencia ontológica. Dentro de este orden de ideas, en la Declaración Universal de los Derechos Humanos, aprobada por la Asamblea General de las Naciones Unidas el 10 de diciembre de 1948, en el Preámbulo se expresó lo siguiente: “Considerando que la libertad, la justicia y la paz en el mundo tienen por base el reconocimiento de la dignidad intrínseca y de los derechos iguales e inalienables de todos los miembros de la familia humana”.
What North Carolina’s Health Workforce Data Can—and Can’t—Tell Us
Authors:   Cecil G. Sheps Center for Health Services Research, Campbell, PharmD, JD Hilary A.
Published: January 2023

Workforce demand data are difficult to track, and it's even harder to know how many health care workers are truly needed to improve the state's health.
Keeping North Carolina’s Health Care Workforce Well
Authors:   North Carolina Healthcare Association, Kelly, CHC Tatyana
Published: January 2023

Supporting the wellness needs of North Carolina's health care workforce is crucial for maintaining a robust health care delivery system for all North Carolinians.
How North Carolina Can Best Respond to Long-Term Services and Supports Needs
Authors: Richard Dave
Published: January 2023

Our long-term services and supports needs are growing, and North Carolinians have an opportunity to respond by working together across all sectors of care.
Fortifying North Carolina’s Workforce for Health to Meet Current and Future Challenges
Authors: Lyda-McDonald, MSPH Brieanne , Miller, MA, MPH Alison , Ries, MPH Michelle G. , Colville, MSW, MSPH Kathleen , Ugolik Phillips, MS Kaitlin
Published: January 2023

Two new North Carolina Institute of Medicine task force reports make recommendations for bolstering the state's public health workforce.
Experimental investigation for heat transfer augmentation method of jet impingement using a fluid of different concentrations of water and ethylene glycol (EG)
Authors: LAHANE Subhash , DESHMUKH Prashant , NARGADE Manoj
Published: January 2023

In the modern world, with rapid inventions in microscale electronics, devices suffers undesirable internal heat generation and, due to their tiny shapes, undergo large heat flux conditions. This emphasizes the development of effective and efficient heat dissipation methods to boost their performance and keep them in safe working conditions. The jet impingement cooling method is used for cooling purposes in many engineering applications, and is popular for quick removal of heat from the solid surfaces. The present experimental study is an investigation of effect impingement of jet of water and ethylene glycol mixture over a heated surface. The blending of ethylene glycol (C2H6O2) with water (H2O) as a base fluid enhances the average (convective) heat transfer coefficient (HTC). The cooling fluid with different concentrations of C2H6O2 varying from 10%, 25%, 50%, and 100% shows higher values of average convective coefficient at similar flow conditions than pure water. The fluid having mixture proportions 50% C2H6O2 and H2O shows an optimum value for heat transfer enhancement in the range of 30% to 75% than pure water at the same flow rates. It can be noted that based on mechanical stability and the cost associated, the experimental results reveal that the optimum value of the concentration of C2H6O2 in water is 50% for maximum heat transfer and at higher values of C2H6O2 hamper the mechanical stability and causes higher pumping power due to increase in viscosity of the fluid.
Effect of module operating temperature on module efficiency in photovoltaic modules and recovery of photovoltaic module heat by thermoelectric effect
Authors: KAYABAŞI1 Ramazan , KAYA Metin
Published: January 2023

One of the parameters affecting the efficiency of photovoltaic (PV) modules and PV systems is the temperature. The factors that increase the temperature in PV modules cause loss of efficiency. In this study, experiments have been conducted with the aim of re ducing the module temperature. For this purpose, four polycrystalline and four monocrystalline PV modules, all with the same features, were used. A pair of polycrystalline and monocrystalline modules were used as reference modules. The aim of this study is to reduce the operating temperature of the modules, while also decreasing the transient temperature fluctuations in the system, in order to prevent the loss of efficiency. For this reason, current, voltage and power values of PV modules have been examined and the relationship between these values and module temperature has been explained. As a result, temperature values were measured at 30-80°C in reference modules, 30-50°C in heat pipe modules, 30-37°C in modules using heat pipes and phase-changing material, and 30-66°C in modules using phase-changing material with flexible surfaces. If the PV module operating temperature is increased by 35°C, the module efficiency decreases by 10%. Heat pipe and PCM balance the temperature in PV/T/PCM monocrystalline and polycrystalline modules. In PV/T/PCM modules, efficiency loss caused by temperature increase is 1%. In addition, electrical energy is produced from the heat accumulated on the surface of the PV module by means of Thermoelectric Generator (TEG). When the temperature difference between the surfaces is 15°C, the naturally cooled TE provides 0.45V energy output, while the forced-cooled TEG provides 0.97V energy output. As the temperature gap between the surfaces increases, the voltage and current values of the TEG also increase. Briefly, TEG’s power values increase up to 5W depending on the temperature gap between surfaces.
Prescription pattern in ischemic heart disease inpatients at B. P. Koirala Institute of Health Sciences: a cross sectional study
Authors: Rai Dillisher , Rauniar Gajendra Prasad , Shah Prashant , Pandey Dipesh R. , Mandal Namita K. , Sarraf Deependra P.
Published: January 2023

Background: Drug utilization pattern studies seek to screen, evaluate and suggest appropriate modifications in prescription practices. It would help to make patient care rational and cost effective. Objective was to analyze the drug prescribing pattern for treatment of ischemic heart disease (IHD).
Methods: A prospective cross-sectional observational study was conducted in patients of IHD admitted in intensive coronary care unit and medicine ward for the period of six months. Data were collected in preformed case record form. The data were analyzed for drug use indicators, demographic parameters, morbidities, pattern of drug use using Microsoft excel 2010.
Results: A total of 145 patients were enrolled out of that 89 (61.38%) were males. The mean age was 60.01±12.71 years and majority (26.89%) belonged to age group of 61-70 years. A total of 1208 drugs were prescribed in 145 patients. Most frequently prescribed drugs were antiplatelet group of drugs 100% encounters, followed by hypo-lipidemics (98.62%). Average number of drugs per encounter was 8.33 and percentage of drugs prescribed by generic name was 5.04%. 
Conclusions: IHD was more common in males than females. The most commonly prescribed drug classes were anti-platelet drugs followed by hypolipidemic agents.
The ICH guidelines in practices: Stress degradation studies on botulinum toxin and validation of developed stability-indicating HPLC method
Authors: Bhale Sonal
Published: January 2023

A fast, simple, reliable and accurate RPHPLC analytical method was developed for the evaluation of botulinum toxin, and the developed method was subsequently validated according to ICH guidelines in sterile dosage form for stability studies. A C18 column with a flow rate of 2 ml/min was selected. The mobile phase chosen consisted of sodium phosphate buffer (0.05 M) at pH 2.8 and acetonitrile in a ratio of 30:70 respectively at 214 nm. Measured at an Rt of 2.1 min. 10 minutes running time. Linearity and range were observed at concentrations from 1 µg/ml to 10 µg/ml. The method developed was linear with a correlation coefficient of 0.99.

Validation of the method was performed according to ICH guidelines for assay, linearity and range, precision, limit of detection, limit of quantitation, and forced degradation test.
The role of uterine artery colour doppler in intrauterine contraceptive device IUCD – Related Abnormal Uterine Bleeding
Authors: Nath Jayati
Published: January 2023

This study was conducted to assess the role of Uterine Artery Colour Doppler velocimetry in prediction of intrauterine contraceptive device (IUCD) - Related Abnormal Uterine Bleeding. From this study, we concluded that the initial pre-IUCD insertion measurement of uterine artery Doppler PI and RI indices can be used as an useful predictor in Cu-T associated AUB, thus help in reducing the number of IUCD removal and non-compliance by the patient within the first year of insertion.
Eruptive collagenoma: An interesting case report
Authors: Samagani Akshay , Shruthi HN , Prabhu Smitha
Published: January 2023

Eruptive cutaneous collagenoma is a non-familial connective tissue nevi of unknown etiology presented with an abrupt onset. To date, the literatures on eruptive cutaneous collagenoma are extremely rare in India. Herein, we report a rare case of eruptive collagenoma in a 26 year old young male with epilepsy and mental retardation, who presented with multiple asymptomatic papules and nodules over the chest and abdomen with no systemic involvement. There was no positive family history or history of consanguineous marriage, and diagnosis was confirmed histologically.

We report this case due to paucity in Indian literature.
The Future is Now From Before: Youth Climate Activism and Intergenerational Justice
Authors: Theodorou Eleni , Spyrou Spyros , Christou Georgina
Published: January 2023

This paper draws on data from a qualitative study of youth climate activists in Cyprus to explore the notion of temporality implied in how youth interrogate intergenerational relations in the context of their struggle against climate change and the tensions therein. Acknowledging the structural age inequalities that limit their actions, youth activists drew on multiple temporal frames of present, future, and past to delineate a sense of urgency for action to prevent an irreversible catastrophe in the future and to forge a future of hope. In the process, they invited other/older generations to the climate struggle, an opening that came with expressions of ambivalence among some activists.
Migrant Childhoods and Temporalities in India: A Reflective Engagement with Dominant Discourses
Authors: Rajan Vijitha
Published: January 2023

Temporality is recognized as critical to the understanding of childhoods by contemporary scholars of childhood. This paper explores the varying temporalities through which marginal childhoods (and their educational inclusion), particularly those situated in contexts of temporary internal migration, are constructed in the Indian context. Drawing on ethnographic data from the city of Bangalore, this paper problematizes how dominant ideals around migration, childhood, and schooling frame migrant children’s lives through linear temporalities. Furthermore, the paper argues that policy interventions that ostensibly include migrant childhoods do not engage critically with the politics of linear temporality which, in turn, is central to the exclusionary dynamics of migrant children’s schooling.
Pedagogies of Time: “Editing” Textbooks, Timelines, and Childhood Memories
Authors: Chachkhiani Ketevan , Palandjian Garine , Tsotniashvili Keti , Silova Iveta
Published: January 2023

Drawing on the concept of “pedagogies of time,” this article analyzes early literacy textbooks and our own childhood memories of temporal socialization in (post)Soviet Armenia, Georgia, and Latvia. While textbook analysis reveals purposeful socialization of children into modern linear timelines, memory stories interrupt these predetermined trajectories and shift attention toward multiple forms of temporalities that coexist alongside and entangle with each other. Using a speculative thought experiment, we “edit” a chronological timeline in one of the stories from early literacy textbooks as an attempt to simultaneously (re)write the dominant timespaces of socialist modernity and the way childhood appears there.
Childhoods and Time: A Collective Exploration
Authors: Da Rosa Ribeiro Camila , Millei Zsuzsa , Hohti Riikka , Kohan Walter , Leite César Donizetti Pereira , Rudolph Norma , Kvale Sørenssen Ingvild , Szymborska Karolina , Tammi Tuure , Tesar Marek
Published: January 2023

This collective piece explores the philosophical, ontological, and epistemic potentials of analyzing the relations between childhood and time, proposing thought experiments and fieldwork analyses that release childhood from a linear temporality toward (modern) adulthood. Each experiment originating from the authors’ distinct scholarly positionings fractures “modern childhood” and its civilization project, built from the hegemony of linear, sequential, progressive, and principled time.
Evaluation of harvest yield and beverage quality of coffee under ethylene application
Authors: Martynelly Nogueira Gois Caroline , Ferreira Sindynara , Gois José Laurício , Ribeiro Malta Marcelo
Published: January 2023

The coffee plant is characterized by the irregular ripening of its fruits. This uneven ripening often makes it impossible to optimize its harvest, since green fruits are more adhered to the plant than those in the ripe and overripe stages. In addition, it can influence the final product’s beverage quality. The use of ethylene is an alternative to optimize and increase the harvest yield of coffee, besides reducing expenditures on labor and post-harvest ground picking. This study was carried out to examine the harvest yield of coffee variety Mundo Novo IAC 379/19 under different ethylene rates as well as to analyze beverage quality in the different treatments. The experiment was laid out in a randomized-block design with four treatments (ethylene rates: 0, 300, 500, or 700 mL ha-1). The plots consisted of nine plants and three replications, but only the three central plants were evaluated. Results were analyzed by Tukey’s test at a significance level of 5%. The rates of 700 and 300 mL ha-1 provided the lowest amount of green fruits, whereas the percentage of ripe fruits was equivalent between treatments. The treatment with 700 mL ha-1 resulted in the highest percentage of fruits in the overripe stage, among the evaluated rates. Ethylene use did not increase harvest efficiency. Control treatment provided a significantly higher number of green fruits. Additionally, the use of ethylene-induced changes in the chemical composition of the bean and beverage quality.
Nutritional diagnosis in a Conilon coffee plantation in the northern region of the Espírito Santo state
Authors: Fontana Ademir , Pires Ivne Franco , Partelli Fábio Luiz , Campanharo Alex , Rocha Juan Ricardo , Rodrigues Jéssica Dalazen
Published: January 2023

The soils of Coastal Tablelands are characterized by low natural fertility, which reinforces the importance of assessing soil fertility and leaf nutrition of crops. The objective of this study is to present a diagnosis of soil fertility and leaf nutrition of coffee plantations with Conilon from Coastal Tablelands in the northern area of the Espírito Santo state. A total of 49 soil samples were collected at a depth of 0-0.20 m and 49 leaf samples. In the soil, we can find Al3+, Ca2+, Mg2+, K+, (H+Al), SB, V, CTC, pH (water), P Mehlich-1, carbon (C), organic matter (MO), nitrogen (N), Cu2+, Fe2+, Mn2+, Zn2+, and in the leaves N, P, K, Ca, Mg, Cu, Fe, Mn and Zn contents. Soil fertility and leaf nutrition were diagnosed, followed by the identification of deficit elements after comparison with reference coffee crops. In the soil, most coffee plantations have low levels of MO, K, Ca, Mg, Fe, Al and (H+Al), P in excess, and the other attributes at medium levels. As for the leaves, most coffee plantations have low levels of N, P, K, Mg, Cu, Fe, and Zn, Mn at an adequate level and Ca at a high level. The soil and leaf elements evaluated are mostly at lower levels than the reference crops.
Physical-hydric quality of a Regosol under integrated and conventional crop production systems
Authors: Figueiredo Neto Nabor Galvão de , Silva Pedro Luan Ferreira da , Oliveira Flávio Pereira de , Martins Adriana Ferreira , Tavares Danillo Dutra , Campos Milton César Costa
Published: January 2023

Sandy soils have gained increased attention due to the expansion of new agricultural frontiers in Brazil and worldwide, however, they are sensitive to land use changes. The objective was to evaluate the physical-hydric quality of a Regosols under integrated and conventional production systems in the climatic conditions of the semiarid domain of Paraíba, Brazil. The study was carried out in the municipality of Lagoa Seca/PB, Brazil (7°10’15” S, 53°51’43” W, and 640 m of altitude), on a Regosols with a sandy loam textural classification. The experiment was set up in an entirely randomized design, with five treatments and five repetitions. The treatments were composed of: 1) Mombaça grass (Panicum maximum Jacq.) + Maize (Zea mays L.) (M+M); 2) Urochloa decumbens (Stapf) R. D. Webster + Maize (U+M); 3) secondary forest (SF); 4) conventional agriculture area, cultivated with bean (Phaseolus vulgaris L.) (AGR); and, 5) area in regeneration stage (ARS). The following variables were analyzed: flocculation degree, clay dispersed in water, soil porosity (total, macroporosity, microporosity), aeration porosity in the macro pore domain, soil bulk density, hydraulic conductivity, and available water. According to the results, the physical-hydric quality of the soil between the integrated systems was not significant, but compared to the conventional system, it showed satisfactory results. On the other hand, it is concluded that the modification of soil structure in an agricultural area has reduced water availability to plants to 75.20% below what is considered adequate. Long-term studies should be conducted in order to verify the effect of integration systems on improving the physical and structural quality of sandy soils.
List of Professors and Students of the Zhytomyr Academy of 1790
Authors: Antoniuk Danylo
Published: January 2023

The history of educational institutions that operated on the Right Bank of Ukraine in the 18th century is almost unexplored. In part, this can be explained by the lack of sources that could shed light on this aspect of Ukraine’s history. Considering this, the list of students and teachers of the Zhytomyr Academy, which is included in the register of the Roman Catholic population of the Kyiv Voivodeship, is unique. The source provides a list of students and teachers of the local educational institution by name and their ages. The vast majority of students came from noble backgrounds. Many of them belonged to noble families that settled in the Kyiv region and neighboring voivodeships in previous centuries.The list of students and professors of the Zhytomyr Academy is published with the preservation of the original format (table), the spelling is presented without changes, and the language of the source has not been modernized.
Almes, Ivan. Vid molytvy do osvity: Istoriia chytannia chentsiv Lvivskoi yeparkhii XVII–XVIII st. (Lviv: Ukrainskyi katolytskyi universytet 2021), 588 s. (Seriia «Kyivske khrystyianstvo», t. 26)
Authors: Tupytsia Mykhailo
Published: January 2023

Review: Almes, Ivan. Vid molytvy do osvity: Istoriia chytannia chentsiv Lvivskoi yeparkhii XVII–XVIII st. (Lviv: Ukrainskyi katolytskyi universytet 2021), 588 s. (Seriia «Kyivske khrystyianstvo», t. 26)
Die Militarisierung der Heiligen in Vormoderne und Moderne, herausgegeben von Liliya Berezhnaya (Berlin: Duncker & Humblot 2020), 331 s. (Historische Forschungen, Band 122)
Authors: Almes Ivan
Published: January 2023

Review: Die Militarisierung der Heiligen in Vormoderne und Moderne, herausgegeben von Liliya Berezhnaya (Berlin: Duncker & Humblot 2020), 331 s. (Historische Forschungen, Band 122)
Determinants of Economic Growth in Somalia: ARDL Model
Authors: Aden Mohamed Abdisalan , Shire Mohamud Salad
Published: January 2023

Using an autoregressive distributed lag model (ARDL) and error correction technique, this paper investigates the short- and long-run relationships between exports, imports, and FDI on economic growth in Somalia. Secondary data was collected from the SESRIC website. The study spans the years 1995 to 2020. The result of the study revealed short- and long-term relationships between the variables. While FDI and exports have a negative long-term relationship with economic growth, imports have a positive long-term relationship. It also shows that FDI has a negative, short-run insignificant relationship with economic growth, whereas imports and exports have a significant, short-run relationship. Diagnostic tests were applied, and the results demonstrate that the model's validity for Somalia's economic growth is characterized by normality, the absence of serial correlation, and heteroscedasticity
Efeito de modalidades fisioterapêuticas sobre os sinais vitais de crianças traqueostomizadas
Authors: Finato Natalia Maria , Werneck Alexandre Lins , Cavenaghi Simone , Folchine Ana Elisa Rosselli
Published: January 2023

Objetivo: avaliar se a manobra de hiperinsulflação manual com compressão torácica apresenta melhor repercussão para estabilidade sobre os sinais vitais do que a vibrocompressão em crianças traqueostomizadas em respiração espontânea. Método: ensaio clínico prospectivo longitudinal não randomizado com crianças, randomizadas entre dois grupos (G1) que recebeu a manobra de hiperinsulflação com compressão torácica, e outro (G2) realizado a vibrocompressão. Os sinais vitais foram verificados antes e após 15 minutos. Resultados: participaram 33 crianças, das quais 16 no G1 e 17 no G2. O valor de significância (p <0,05) da saturação periférica de oxigênio alcançou: (%) 0,105 x 0,434; frequência cardíaca 0,300 e 0,588; frequência respiratória 0,763 e 0,836; pressão arterial sistólica 0,300 e 0,756; pressão arterial diastólica 0,985 e 0,179; pressão arterial média 0,678 e 0,459. Conclusão: a hiperinsulflação manual com compressão torácica apresentou melhor repercussão clínica; entretanto, não houve significância estatística entre os grupos.