bluuebunny/crossref_metadata_2025 huggingface dataset:
Narrative review on the management of moderate-severe atopic dermatitis in pediatric age of the Italian Society of Pediatric Allergology and Immunology (SIAIP), of the Italian Society of Pediatric Dermatology (SIDerP) and of the Italian Society of Pediatrics (SIP)
Authors: Galli Elena , Fortina Anna Belloni , Ricci Giampaolo , Maiello Nunzia , Neri Iria , Baldo Ermanno , Berti Irene , Bonamonte Domenico , Capra Lucetta , Carboni Elena , Carello Rossella , Caroppo Francesca , Cavagni Giovanni , Chinellato Iolanda , Cipriani Francesca , Comberiati Pasquale , Diociaiuti Andrea , Di Lernia Vito , Duse Marzia , Filippeschi Cesare , Giannetti Arianna , Giovannini Mattia , Licari Amelia , Marseglia Gian Luigi , Pace Manuela , Patrizi Annalisa , Pajno Giovanni Battista , Peroni Diego , Villani Alberto , Eichenfield Lawrence
Published: June 2022

Currently, there are a few detailed guidelines on the overall management of children and adolescents with moderate-severe atopic dermatitis. AD ​​is a complex disease presenting with different clinical phenotypes, which require an individualized and multidisciplinary approach. Therefore, appropriate interaction between primary care pediatricians, pediatric allergists, and pediatric dermatologists is crucial to finding the best management strategy. In this manuscript, members of the Italian Society of Pediatric Allergology and Immunology (SIAIP), the Italian Society of Pediatric Dermatology (SIDerP), and the Italian Society of Pediatrics (SIP) with expertise in the management of moderate-severe atopic dermatitis have reviewed the latest scientific evidence in the field. This narrative review aims to define a pathway to appropriately managing children and adolescents with moderate-severe atopic dermatitis.
Systemic lupus erythematosus dysregulates the expression of long noncoding RNAs in placentas
Authors: Li Hui-hui , Sai Lin-tao , Liu Yuan , Freel Colman I. , Wang Kai , Zhou Chi , Zheng Jing , Shu Qiang , Zhao Ying-jie
Published: June 2022

Background

Systemic lupus erythematosus (SLE) can cause placental dysfunctions, which may result in pregnancy complications. Long noncoding RNAs (lncRNAs) are actively involved in the regulation of immune responses during pregnancy. The present study aimed to determine the lncRNA expression profiles in placentas from women with SLE to gain new insights into the underlying molecular mechanisms in SLE pregnancies.

Methods

RNA sequencing (RNA-seq) analysis was performed to identify SLE-dysregulated lncRNAs and mRNAs in placentas from women with SLE and normal full-term (NT) pregnancies. Bioinformatics analysis was conducted to predict the biological functions of these SLE-dysregulated lncRNAs and mRNAs.

Results

RNA-seq analysis identified 52 dysregulated lncRNAs in SLE placentas, including 37 that were upregulated and 15 downregulated. Additional 130 SLE-dysregulated mRNAs were discovered, including 122 upregulated and 8 downregulated. Bioinformatics analysis revealed that SLE-dysregulated genes were associated with biological functions and gene networks, such as regulation of type I interferon-mediated signaling pathway, response to hypoxia, regulation of MAPK (mitogen-activated protein kinase) cascade, response to steroid hormone, complement and coagulation cascades, and Th1 and Th2 cell differentiation.

Conclusions

This is the first report of the lncRNA profiles in placentas from SLE pregnancies. These results suggest that the aberrant expression and the potential regulatory function of lncRNAs in placentas may play comprehensive roles in the pathogenesis of SLE pregnancies. SLE-dysregulated lncRNAs may potentially serve as biomarkers for SLE.
Growth rate determines prokaryote-provirus network modulated by temperature and host genetic traits
Authors: Liu Zhenghua , Yan Qingyun , Jiang Chengying , Li Juan , Jian Huahua , Fan Lu , Zhang Rui , Xiao Xiang , Meng Delong , Liu Xueduan , Wang Jianjun , Yin Huaqun
Published: June 2022

Background

Prokaryote-virus interactions play key roles in driving biogeochemical cycles. However, little is known about the drivers shaping their interaction network structures, especially from the host features. Here, we compiled 7656 species-level genomes in 39 prokaryotic phyla across environments globally and explored how their interaction specialization is constrained by host life history traits, such as growth rate.

Results

We first reported that host growth rate indicated by the reverse of minimal doubling time was negatively related to interaction specialization for host in host-provirus network across various ecosystems and taxonomy groups. Such a negative linear growth rate-specialization relationship (GrSR) was dependent on host optimal growth temperature (OGT), and stronger toward the two gradient ends of OGT. For instance, prokaryotic species with an OGT ≥ 40 °C showed a stronger GrSR (Pearson’sr= −0.525,P< 0.001). Significant GrSRs were observed with the presences of host genes in promoting the infection cycle at stages of adsorption, establishment, and viral release, but nonsignificant with the presence of immune systems, such as restriction-modification systems and CRISPR-Cas systems. Moreover, GrSR strength was increased with the presence of temperature-dependent lytic switches, which was also confirmed by mathematical modeling.

Conclusions

Together, our results advance our understanding of the interactions between prokaryotes and proviruses and highlight the importance of host growth rate in interaction specialization during lysogenization.
A scrutiny of the relationship between cognitive load and difficulty estimates of language test items
Authors: Noroozi Shadi , Karami Hossein
Published: June 2022

Recently, researchers have expressed their growing concern over the scrutiny of language test items in light of cognitive load theory (CLT). While cognitive load has been central to language learning research, it has not enjoyed due attention in high-stakes language tests. The current study set out to delve into the relationship between difficulty estimates and cognitive load of language test items. To measure cognitive load, examinees’ perceived level of difficulty and response time were considered. In this regard, empirical data were collected from 60 MA students and graduates through a quantitative correlational design. The current study further employed the Rasch model to estimate difficulties of the vocabulary and grammar items of the Iranian university entrance examination (IUEE) for MA in English majors held in 2018 and 2019. The study’s findings revealed statistically significant correlations between difficulty estimates and perceived level of difficulty for vocabulary items. As for grammar items, no statistically significant correlations were detected between the variables. Whereas the results indicated strong positive correlations between response time and difficulty estimates regarding vocabulary items, no statistically significant correlations were observed between the variables concerning grammar items. All in all, perceived level of difficulty, response time, and difficulty estimates appeared to be sound indicators of cognitive load with respect to vocabulary test items, but not with regard to grammar test items. The implications of the findings will be discussed.
A cross-cultural study of the proximity of clothing to self between millennial women in South Korea and Mongolia
Authors: Choi Sun Young , Jo Jeyeon , Lee Yuri , Ha Jisoo , Lee Joeun
Published: June 2022

As a part of material culture, clothing embodies the cultural specificity based on the influence of that culture on individuals. The cultural value model of Hofstede broadly describes the dimensional characteristics of each country. At the same time, the proximity of clothing to a self-scale represents the level of psychological closeness of clothing to identity. Even though it is theoretically correct that these two concepts—culture and clothing that expresses one’s self—are related, few studies have highlighted this connection. In this study, we investigated the effect of cultural values on how the individuals involve their clothing with their social identity by focussing on the differences between two culturally different countries: South Korea and Mongolia. Quantitative surveys from 179 in South Korea and 262 in Mongolia and t-tests showed cultural differences in both countries’ individualism and indulgence vs their restrained disposition. The multiple regression analysis results revealed that uncertainty avoidance and indulgence correlate with three dimensions in the proximity of clothing to self: clothing to self as structure, clothing as a response to others’ judgements, and clothing-related to self-esteem. The moderating effect of each country was not found. This result implies that knowing the cultural values of a particular group can infer their clothing consciousness. Thus, when fashion companies target millennial women in South Korea and Mongolia and establish a more significant presence abroad, examining a country’s or a group’s culture helps identify the target market's clothing perceptions.
Falciform ligament abscess with disseminated intrahepatic foci: a case report
Authors: Kuribara Tadao , Shigeyoshi Itaru , Ichikawa Tatsuo , Osa Kiyoshi , Inoue Takeshi , Ono Satoshi , Asanuma Kozo , Kaneko Shiori , Sano Takayuki , Matsubara Kouta , Irie Naoko , Suzuki Kanako , Iai Akira , Ishizu Hideki
Published: June 2022

Background

Falciform ligament abscess (FLA) is a rare disease, and its diagnosis can be challenging without typical image findings of an abscess. We report a patient with FLA that presented as a mass, with an indistinct border between it and the liver, in addition to disseminated foci within the liver. This made it difficult to determine whether it was FLA or a malignancy.

Case presentation

A 69-year-old man presented with epigastric pain. Contrast-enhanced computed tomography revealed a 25-mm mass below the middle of the diaphragm. Based on an initial diagnosis of infection of the falciform ligament, we administered conservative antibiotic treatment and there was initial improvement in the patient’s clinical condition and laboratory data. However, he continued to experience mild epigastric pain. A month later, imaging studies revealed enlargement of the falciform ligament mass and the emergence of a new nodule in the liver, whereas laboratory findings showed re-elevated C-reactive protein levels. Since conservative treatment had failed, we decided to perform surgery. Considering the imaging study findings, malignant disease could not be ruled out. Based on the operative findings, we performed combined resection of the falciform ligament, left liver, and gallbladder. Histopathological examination of the resected specimens revealed extensive neutrophil infiltration and the presence of giant cells and foam cells within the lesions. These findings were indicative of abscess.Pseudomonas aeruginosawas cultured from the pus in the falciform ligament mass and bile in the gallbladder. Although multiple abscesses postoperatively developed in the residual portion of the liver, they could be treated through antibiotic therapy.

Conclusions

FLA can spread to both adjacent and distant organs via its rich vascular and lymphatic networks. When FLA displays atypical image findings and/or an atypical clinical course, it can be difficult to distinguish it from malignant disease. In such cases, surgical treatment, with intraoperative pathological diagnosis, should be attempted.
Anemia and its associated factor among adolescent school girls in GODEY and DEGEHABUR council Somali region, eastern Ethiopia
Authors: Ahmed Abdirahman , Mohammed Abdulkarim
Published: June 2022

A cross-sectional study was conducted in a higher secondary school in Godey and Degehabur council to estimate the prevalence of anaemia among school-going adolescent girls and to identify the associated factors. Haemoglobin levels were assessed directly in the school. Data related to socio-demographic, socio-economic characteristics, dietary habits, past health status and anaemia related knowledge among adolescents’ girls were collected by interview method and analyzed with the help of SPSS version 25. The prevalence of anaemia was found to be 31.5% among adolescent girls. Family size ≥5 people and lack of anaemia knowledge were independent predictors of anaemia. Therefore, the present study emphasizes the need for development of health and nutrition education strategies to improve dietary habits, family planning, and intermittent iron-folic acid supplementation with intensifying adolescent anemia prophylaxis programs.
Efficacy of a digital cognitive behavioral therapy for insomnia in people with low back pain: a feasibility randomized co-twin and singleton-controlled trial
Authors: Ho Kevin K. N. , Simic Milena , Pinheiro Marina B. , Miller Christopher B. , Ferreira Manuela L. , Grunstein Ronald R. , Hopper John L. , Ordoñana Juan R. , Ferreira Paulo H.
Published: June 2022

Background

Digital cognitive behavioral therapy for insomnia (CBT-i) in people with low back pain (LBP) may be efficacious in improving both sleep and pain; and twin trial designs provide greater precision of treatment effects by accounting for genetic and early environmental factors. We aimed to determine the feasibility of a trial investigating the efficacy of a digital CBT-i program in people with comorbid symptoms of insomnia and LBP, in twins and people from the general community (singletons).

Methods

Thirty-two twins (16 pairs) and 66 singletons with comorbid symptoms of insomnia and LBP (> 6 weeks duration) were randomized to digital CBT-i (intervention) or educational program (control) for 6 weeks. The digital CBT-I, Sleepio (developed by Big Health Inc.), was an online interactive, automated, personalized course comprising of six sessions, once a week. The education program was six emails with general sleep information, once a week. Participants were blinded to their group allocation and offered the alternative intervention at the completion of the study. Feasibility outcomes included recruitment and follow-up rates, data collection and outcome measure completion, contamination (communication about trial interventions), acceptability (adherence), credibility, and participants’ experience of the intervention.

Results

Sixteen out of 722 contacted twin pairs were recruited (recruitment rate = 2.2%). Twins were recruited between September 2015 and August 2018 (35 months) and singletons between October 2017 and Aug 2018 (10 months). Follow-up rates for post-intervention and 3-month follow-up were 81% and 72% for twins and 82% and 78% for singletons respectively. Adherence rates (percentage of sessions completed out of six) for the digital CBT-i were 63% for twins and 55% for singletons. Contamination (speaking about the study to each other) was present in two twin pairs (13%). Written or verbal feedback (n = 21) regarding the digital CBT-i intervention from participants were positive (n = 11), neutral (n = 5), or negative (n = 6).

Conclusions

Online CBT-i was received favorably with people with comorbid symptoms of insomnia and LBP. While the online data collection was successful, strategies need to be implemented to improve adherence, follow-up, control group credibility (for digital CBT-i), and twin recruitment rates (for twin trials).

Trial registration

Australian New Zealand Clinical Trials Registry (ACTRN12615000672550). Registered 29 June 2015
Exploring how to improve access to psychological therapies on acute mental health wards from the perspectives of patients, families and mental health staff: qualitative study
Authors: Berry Katherine , Raphael Jessica , Haddock Gillian , Bucci Sandra , Price Owen , Lovell Karina , Drake Richard J. , Clayton Jade , Penn Georgia , Edge Dawn
Published: June 2022

Background

Psychological therapy is core component of mental healthcare. However, many people with severe mental illnesses do not receive therapy, particularly in acute mental health settings.

Aims

This study identifies barriers to delivering and accessing psychological therapies in acute mental health settings, and is the first to recommend how services can increase access from the perspectives of different stakeholders (staff, patients and carers).

Method

Sixty participants with experiences of acute mental health wards (26 staff, 22 patients and 12 carers) were interviewed about barriers to accessing therapy in in-patient settings and how therapies should be delivered to maximise access.

Results

Four themes were identified: (a) ‘Models of care’, including the function of in-patient wards, beliefs about the causes of mental health problems and the importance of strong leadership to support psychosocial interventions; (b) ‘Integrated care’, including the importance of psychologists being ward-based, as well as having strong links with community teams; (c) ‘Acute levels of distress’, including factors that aggravate or ameliorate the impact of this on engagement in therapy; and (d) ‘Enhancing staff capability and motivation’, which is influenced by contextual issues.

Conclusions

It is possible to improve access to therapy through strong leadership (that is supportive of talking treatments), flexible delivery of therapy (that considers short admissions) and a whole-systems approach that promotes ward staff understanding of the psychosocial causes of mental illness and staff well-being. It is essential to ensure continuity between in-patient and community therapy services, and for wards to have physical space to carry out therapy.
Medication Adherence Among Adults With Comorbid Chronic Conditions Initiating Oral Anticancer Agent Therapy for Multiple Myeloma
Authors: Gatwood Justin , Dashputre Ankur , Rajpurohit Abhijeet , Gatwood Katie , Mackler Emily , Wallace Leah , Farris Karen , Rizvi-Toner Amna , Farley Joel
Published: June 2022

PURPOSE:

Increased use of oral anticancer agents (OAAs) has empowered adults with multiple myeloma (MM) to manage their oncolytic therapy, but such a shift may result in issues with medication use, particularly among patients being concurrently treated for pre-existing, multiple chronic conditions.

METHODS:

This retrospective cohort study used 2013-2018 commercial and Medicare claims data to assess medication use in adults with MM. To be included, adults (18 years and older) must have been diagnosed with and had 2+ claims for an OAA, had continuous enrollment for 12 months before and after OAA initiation, and have been previously diagnosed with and had prescription fills for 2+ select chronic conditions. The proportion of days covered metric assessed medication adherence and was compared for 12 months before and after the OAA initiation by Wilcoxon signed-rank tests, McNemar's tests, and difference-in-differences models.

RESULTS:

The mean OAA adherence in the first year of therapy was 58.3% (standard deviation: 24.5) and 65.1% (standard deviation: 27.01) for commercial and Medicare patients, respectively. Adherence and the proportion adherent (proportion of days covered ≥ 80%) to comorbid therapies generally declined in the first year after OAA initiation. Changes in medication use were particularly noticeable among those on antihypertensive therapy: adjusted analyses uncovered a 2.5% (Medicare) and 5.2% (commercial) difference in adherence to these medications between those initially adherent and nonadherent to OAA therapy (both P < .05).

CONCLUSION:

Initiating OAA therapy in adults with MM may complicate an already complex treatment regimen, resulting in poor overall medication adherence in patients with multiple comorbid conditions.
CZO films: Effect of different post-annealing temperatures on electron-phonon interactions, steepness parameters, coordination numbers, optical mathematical equations, and skin depth
Authors: Dalouji Vali , Rahimi Nasim
Published: June 2022

The CZO films annealed at 500°C are smoother and they have the maximum value of electron-phonon interaction. The CZO films annealed at 500°C have the maximum value of optical density. The absorption edge of films up to 500°C has a redshift and over 500°C they have a blue shift. The CZO films annealed at 500°C have the minimum value of band-to-band transitions energy. The as-deposited CZO films are more disordered. The empirical optical mathematical equation from linear fitting for these films was given as

. It was demonstrated that values of the steepness parameters of CZO films are represented by a decreasing function while electron-phonon interactions by an increasing function with increasing annealing temperature. This may be ascribed to a change in iconicity and action valences of CZO films. Considering

,

, and

for ZnO, the coordination number constants

were calculated and for CZO films annealed at 600°C, β has a minimum value about of 0.18. Swanepoel method parameters also were obtained.
“Photography”: An Introduction
Authors: Dewan Deepali
Published: June 2022

This editor's introduction to the issue explores the instability of photography as a material object and as a concept and how photography in and of the geopolitical imaginary of Asia expands notions of the photographic.
Hip Contact Force Magnitude and Regional Loading Patterns Are Altered in Those with Femoroacetabular Impingement Syndrome
Authors: SAVAGE TREVOR N. , SAXBY DAVID J. , LLOYD DAVID G. , HOANG HOA X. , SUWARGANDA EDIN K. , BESIER THOR F. , DIAMOND LAURA E. , EYLES JILLIAN , FARY CAMDON , HALL MICHELLE , MOLNAR ROBERT , MURPHY NICHOLAS J. , O’DONNELL JOHN , SPIERS LIBBY , TRAN PHONG , WRIGLEY TIM V. , BENNELL KIM L. , HUNTER DAVID J. , PIZZOLATO CLAUDIO
Published: June 2022

Purpose

The magnitude and location of hip contact force influence the local mechanical environment of the articular tissue, driving remodeling. We used a neuromusculoskeletal model to investigate hip contact force magnitudes and their regional loading patterns on the articular surfaces in those with femoroacetabular impingement (FAI) syndrome and controls during walking.

Methods

An EMG-assisted neuromusculoskeletal model was used to estimate hip contact forces in eligible participants with FAI syndrome (n = 41) and controls (n = 24), walking at self-selected speed. Hip contact forces were used to determine the average and spread of regional loading for femoral and acetabular articular surfaces. Hip contact force magnitude and region of loading were compared between groups using statistical parametric mapping and independent t-tests, respectively (P < 0.05).

Results

All of the following findings are reported compared with controls. Those with FAI syndrome walked with lower-magnitude hip contact forces (mean difference, −0.7 N·BW−1; P < 0.001) during first and second halves of stance, and with lower anteroposterior, vertical, and mediolateral contact force vector components. Participants with FAI syndrome also had less between-participant variation in average regional loading, which was located more anteriorly (3.8°, P = 0.035) and laterally (2.2°, P = 0.01) on the acetabulum but more posteriorly (−4.8°, P = 0.01) on the femoral head. Participants with FAI syndrome had a smaller spread of regional loading across both the acetabulum (−1.9 mm, P = 0.049) and femoral head (1 mm, P < 0.001) during stance.

Conclusions

Compared with controls, participants with FAI syndrome walked with lower-magnitude hip contact forces that were constrained to smaller regions on the acetabulum and femoral head. Differences in regional loading patterns might contribute to the mechanobiological processes driving cartilage maladaptation in those with FAI syndrome.
Identifying the association of women’s empowerment with reproductive and maternal health practices using a cross-sectional study in the context of self-help groups in rural India
Authors: Irani Laili , Verma Supriya , Mohanan P. S. , Hazra Avishek
Published: June 2022

Background: Globally, women’s empowerment is captured through different combinations of indicators related to their collective and individual empowerment. In this paper, the association of diverse domains related to women’s collective and individual empowerment on their reproductive and maternal health practices were assessed. Collective empowerment referred to a cluster of indicators measuring mutual support, rights, and access to services women received, as a result of membership in self-help groups (SHGs) focused on micro-finance activities. Women’s individual empowerment was measured through their perception to make decisions on their own, be mobile, financially self-reliant, self-confident in expressing themselves, having self-esteem and being free from spousal violence.

Methods: Cross-sectional data were collected in 2017 from 2,197 SHG members across 57 administrative blocks of Uttar Pradesh, India. Using exploratory and confirmatory factor analysis, the sub-domains of individual and collective empowerment were developed. The reproductive and maternal health indicators included antenatal care, delivery preparedness, postnatal care and current contraceptive use. Bivariate and multivariate analyses, using logistic regression, were carried out to measure the association of sub-domains of women’s empowerment with health practices.

Results: Collective and individual empowerment were independently and jointly associated with correct health practices. Women with greater empowerment through independent mobility, high self-esteem, access to financial resources, and confidence in interacting with a frontline worker, were more likely to access antenatal care. Similarly, delivery preparedness—which entailed deciding on the place of delivery, arranging for transportation during labor, and managing expenses for the delivery—was positively influenced by collective support from fellow SHG members. Receiving postnatal care was positively associated with self-confidence and financial autonomy, and current family planning method use was positively associated with self-confidence, lower spousal violence and confidence in support from the group.

Conclusions: Women’s collective and individual empowerment were independently and jointly positively associated with health outcomes among SHG members.
A Software Package and Data Set for the Personal Protective Equipment Matching Problem During COVID-19
Authors: Samorani Michele , Bala Ram , Jacob Rohit , He Shuhan
Published: June 2022

During the COVID-19 pandemic, Get Us PPE provided a platform aimed at connecting prospective donors of personal protective equipment (PPE) to prospective recipients of PPE. Requests by donors and recipients were collected over time, and periodically, the PPE matching problem was solved in order to instruct each donor to ship a certain quantity of PPE to a given recipient. The objectives of the PPE matching problem include maximizing the recipients’ fill rate, minimizing the total shipping distance, minimizing the holding time of PPE, and minimizing the number of shipments of each donor. This paper presents a software framework to facilitate the development of methodologies to solve the PPE matching problem and their testing on a real-world data set collected by Get Us PPE during the COVID-19 pandemic. Both software and data set are available on GitHub.
Financial wellbeing
Authors: Swales Paul
Published: June 2022

In the first of a series of articles on financial management, Paul Swales looks at the importance of planning ahead.
Obesity in the UK
Authors: Lloyd-Rees Kimberley
Published: June 2022

Kimberley Lloyd-Rees explains what DCPs can do to help.
Supporting your colleagues
Authors: Frisby Claire
Published: June 2022

Claire Frisby talks to Heidi Grimwood about Molar Mentoring.
A guide to data breaches and indemnity issues
Authors: McGuire Dawn
Published: June 2022

Indemnity issues surrounding data breaches can be complex and it is important that practices are aware of the requirements. Dr Dawn McGuire, Medicolegal Consultant at Medical Protection, explains
Türk müziği keman icracılığında çifte kiriş icra tekniği: Kemanî Âmâ Recep’in Rast taksim örneği
Authors: Bükülmez Haluk
Published: June 2022

Türk müziği keman icracılığında müzikal ifadeyi güçlendirmek amacıyla kullanılan icra tekniklerinden biri de Çifte Kiriş icra tekniğidir. Çifte Kiriş icra tekniğine yönelik elimizde bulunan en önemli kaynak ise Kemanî Âmâ Recep’in Çifte Kiriş tekniği ile icra etmiş olduğu Rast makamındaki taksim örneğidir. Bu çalışmada Türk müziği keman icracılığında Çifte Kiriş icra tekniğinin nasıl meydana getirildiği, Türk müziği keman icra tarihine bakıldığında günümüzde neden unutulmaya yüz tuttuğunun belirlenmesi, Kemani Âmâ Recep’in Çifte Kiriş icra tekniği ile Rast makamındaki taksim icrasının tahlili yapılarak Çifte Kiriş icra tekniğinde gereken diğer teknik özelliklerin belirlenmesi için nitel araştırma yöntemi kullanılmıştır. Çifte Kiriş icra tekniğine yönelik oluşturulan tel düzenin; ikinci telin alt köprüden kaldırılarak birinci tele yakınlaştırılması ve daha sonra ikinci telin, birinci telin frekansının yarısı kadar olan değerde akortlanması ile oluşturulduğu ortaya konulmuştur. Bahsi geçen icra tekniğinin gerçekleştirilebilmesi için özellikle 1, 3 ve 4. konum değişikliklerine hâkimiyet gerekliliği ortaya konulmuştur.
Ev stüdyoları akustiğinde çalışma masalarından kaynaklanan erken yansımaların işitilen ses üzerindeki etkileri üzerine bir simülasyon çalışması
Authors: Vergili Suat
Published: June 2022

Akustikte, müziğin yaratıldığı, kayıt, mix ve mastering uygulamalarının gerçekleştirildiği odalar, kritik dinleme odaları altında sınıflandırılır. Profesyonel stüdyolarda bu alanlar ciddi mimari ve akustik tasarım süreçleri sonucunda oluşmaktadır ve hoparlörlerden çıkan direkt sesin dinleyiciye minimum değişim ile ulaşması temeldir. Günümüzde ev stüdyoları da önemli kritik dinleme alanları sayılmaktadır. Ancak ev stüdyoları, akustik kriterlerin sağlanmasında, tutarsızlıkların, zorlukların hatta imkansızlıkların görüldüğü kritik dinleme odalarıdır. Ev stüdyoları gibi küçük hacimli kritik dinleme odalarında erken yansımalar önemli duyum sorunları yaratırlar. Hoparlörlerden odaya yayılan direkt sesteki “duruluk” hoparlörlerin yan yüzeylerinden, tavan ve zeminden, çalışma masalarından ve masa üzerine yerleştirilen objelerden yansıyan erken yansımalar ile bozulmakta ve odadaki frekans tepkisinde istenmeyen etkiler oluşmaktadır. Bu makalede ev stüdyolarında erken yansımalarla ilişkili olan akustik bozulmalar ele alınarak, odalarda yer alan çalışma masalarından kaynaklı duyusal etkiler simülasyon yöntemi ile değerlendirilmiştir. Ölçüm ve değerlendirmeler sonucunda çalışma masalarından kaynaklanan erken yansımaların alt ve orta frekansların işitsel algısında belirgin olumsuz etkileri olduğu gözlemlenmiştir.
Special meal of the Acehnese, Indonesia during Ramadhan
Authors: MANAN ABDUL , SALASIYAH CUT INTAN , RAHMAWATI SRI , SAPRIJAL SAPRIJAL , KHAIRISMAN KHAIRISMAN , CHAIRUNNISAK CHAIRUNNISAK
Published: June 2022

Abstract. Manan A, Salasiyah CI, Rahmawati S, Saprijal, Khairisman, Chairunnisak. 2022. Special meal of the Acehnese, Indonesia during Ramadhan. Biodiversitas 23: 1187-1195. Ie Bu Peudah is a special meal of Acehnese, Indonesia society in every month of Ramadhan consisting of 44 kinds of mixed substances. All mixed ingredients are pounded or mashed using a special mortal done together and collectively. This study aimed to explore more deeply the origin of the making Ie Bu Peudah, its usefulness, social functions, and knowledge transfer amongst community. This descriptive analysis study employed observation, interview, questionnaire, and documentation to collect the data. The obtained data were analyzed by reducing, displaying, and concluding stages. The findings showed that the history of Ie Bu Peudah was carried by Indian traders that visited Aceh then the meal was recreated and modified by the local people in the sultanate of Aceh during 15 AD and was passed down over generations until today. Its efficacy was for body immunity, including the danger of coronavirus and healing many diseases like a tumor as it contains antioxidants, antibiotics, antiseptic, etc. Besides protecting from many diseases, Ie Bu Peudah also has the social functions which were to strengthen the friendship (silaturrahmi) among traditional figures and local people, strengthening the unity, glorifying the month full of blessing, preserving the harmony between the leaders of the village and people and upholding the values of togetherness during the month of Ramadhan.
Effect of gamma irradiation on the germination, pollen viability, and morpho-agronomic of Pachyrhizus erosus cv. Kota Padang
Authors: HAYATI P.K. DEWI , WITARI SISKA , ROZEN NALWIDA , SUTOYO SUTOYO , WIDIARSIH SASANTI
Published: June 2022

Abstract. Hayati PKD, Witari S, Rozen N, Sutoyo, Widiarsih S. 2022. Effect of gamma irradiation on the germination, pollen viability, and morpho-agronomic of Pachyrhizus erosus cv. Kota Padang. Biodiversitas 23: 1231-1238. Yam bean or Pachyrhizus erosus (L.) Urb., an unexploited plant that produces the storage root tuber, is used in a variety scale of food processing and cosmetic industries in Indonesia. Novel approaches to induce variability in yam bean cv. Kota Padang will accelerate the breeding efforts and improvement of the cultivar. The purpose of the study was to elucidate the effects of gamma irradiation on seed germinability, pollen viability, and morpho-agronomic performance of yam bean cv. Kota Padang. Seeds were irradiated with gamma-rays on 0, 100, 150, 200, 300, 400, and 500 Gy, then LD50 was determined based on the germination percentage. Observation of the irradiated yam bean growth in the field was carried out individually. Results showed that gamma irradiation decreased seed germinability, pollen viability, and agronomic traits. Still, it increased the variability of the traits among the mutant populations, except for the number of branches. Correlation analysis confirmed the results, indicating that selection in the next M2 generation must consider semi-dwarf and pod yield performances. The LD50 was 150 and 176 Gy; hence, the irradiation doses of 150 and 200 Gy were appropriate in producing high genetic diversity with low physical damage in yam bean cv. Kota Padang.
Performance of tomato M7 mutant lines and their similarities to the parents based on SSR markers
Authors: ARRUFITASARI PUTRI NUR , SUTJAHJO SURJONO HADI , WIRNAS DESTA
Published: June 2022

Abstract. Arrufitasari PN, Sutjahjo SH, Wirnas D. 2022. Performance of tomato M7 mutant lines and their similarities to the parents based on SSR markers. Biodiversitas 23: 1239-1245. Tomato cultivation in the lowlands can be an alternative to increase tomato production so that high-yielding and lowland adaptive varieties are required. This study was aiming at determining the performance of  M7 mutant lines and their similarities to the parents based on SSR markers. The experiments were conducted at KP Leuwikopo (250 m asl) and Plant Molecular Biology Laboratory, IPB University, Indonesia. The results showed that the G4 line had the highest productivity among the tested genotypes (36.72 ton ha-1) and significantly differed from all check varieties. The highest number of fruit per plant was 51.67 in the G7 line. On the other hand, G2, G3, G7, G8, and G10 lines had the lowest percentage weight and the number of fruits cracking and were not significantly different from the check varieties (Tora and Mawar). A total of 7 SSR primers detected 87 alleles with a range of 7-15 alleles per locus. The similarity between mutant lines and their parents ranged from 44-69%. The mutant most closely resembled the parent was the G3 line, while the most different based on molecular markers was the G9 line.
Species diversity of subterranean ants in Rangsit Marsh, Khlong Luang District, Pathum Thani Province, Thailand
Authors: WANNA CHANATE WANNA , BOONMAN NARUMON , PHAKPAKNAM SIRIRAT , PIKULTHONG VACHIRAPORN , JAITRONG WEEYAWUT , SOI-AMPORNKUL RUNGTIP
Published: June 2022

Abstract. Wanna C, Boonman N, Phakpaknam S, Pikulthong V, Jaitrong W, Soi-Ampornkul R. 2022. Species diversity of subterranean ants in Rangsit Marsh, Khlong Luang District, Pathum Thani Province, Thailand. Biodiversitas 23: 1283-1292. The present study aimed to compare species diversity and abundance of subterranean ants in three habitats: scrub forest, forest plantations, and glades at Rangsit Marsh, Khong Luang District, Pathum Thani Province, Thailand. The ant samples were collected twice a month during the rainy season (June-August 2019) and dry season (September-November 2019) using a pitfall trap in the soil. A total number of 6,305 individuals belonging to 4 subfamilies, 16 genera, and 16 species of ants were recorded. The subfamilies Myrmicinae comprising 6 species were the most prevalent, followed by 4 species of Formicinae, 3 species of Dolichoderinae, and 3 species of Ponerinae. The Shannon-Wiener species diversity index indicated the diversity was the highest in the glade (1.951), followed by the forest plantation (1.635), and lastly the scrub forest (0.419). Sorensen’s similarity coefficient to determine the similarity in community composition was highest between the forest plantation and the glade at 63.40%, and then between the scrub forest and the forest plantation at 44.30%, and between the scrub forest and the glade at 39.60%. This indicated that both ant species diversity and community composition were distinctly varied in these three sites. The rainy season revealed higher species richness than the dry season. The highest occurrence of ant species was for Iridomyrmex anceps (Roger, 1863), which was recorded as uncommon and was the most abundant species in the glade, while Anoplolepis gracilipes (Smith, 1857) and Carebara diversa (Jerdon, 1851) were the most abundant species in the scrub forest and forest plantation, respectively. Therefore, this study revealed that different habitat types and seasons resulted in differences in subterranean ant species diversity.
Whole-genome analysis of Bacillus subtilis G8 isolated from natto
Authors: DIKSON DIKSON , VICTOR HANS , JONG DELVIN , SANJAYA ASTIA , SAMANTHA ARIELA , JO JUANDY , PINONTOAN REINHARD
Published: June 2022

Abstract. Dikson, Victor H, Jong D, Sanjaya A, Samantha A, Jo J, Pinontoan R. 2022. Whole-genome analysis of Bacillus subtilis G8 isolated from natto. Biodiversitas 23: 1293-1300. Bacillus subtilis-fermented soy-based food is associated with multiple health benefits. Various bacterial strains have been isolated from it, includingB. subtilisG8, recent isolation from Japanese natto commercially available in Indonesia. Both 16S rRNA gene sequencing and fibrinolytic activity characterization have been performed and published in prior studies. After comparison to the genome of a natto-isolated reference strain (i.e., B. subtilisBEST195), the B. subtilis G8 genome showed a similar guanine-cytosine (GC) content, predicted number of coding sequences (CDS) and predicted number of tRNA genes, but had a shorter sequence length and fewer predicted rRNA genes. Further analysis using multiple genome alignment with Mauve, average nucleotide identity (ANI) matrix calculation, and phylogenetic inference indicated that B. subtilis G8 was more related to natto-derived B. subtilis than to cheonggukjang-derived B. subtilis and B. subtilis 168. Finally, sequence analyses of a gene encoding nattokinase as well as two genes regulating poly-gamma-glutamic acid (?-PGA) production in B. subtilis G8, B. subtilis BEST195 and B. subtilis 168 clearly indicated that B. subtilis G8 is able to produce nattokinase and ?-PGA, which both contribute to natto’s fermentation process. Therefore, it is proposed that B. subtilis G8 should be reclassified as B. subtilis subsp. natto G8 to reflect that it is a natto-derived B. subtilis strain.
Assessing the relationship between biodiversity conservation and slow food culture in selected protected areas in Albania
Authors: Shumka Spase , BERBERI ENKELEDA , KULICI MANJOLA , MUÇAJ SUADA , VLADI FLORJAN
Published: June 2022

Abstract. Shumka S, Berberi E, Kulici M, Muçaj S, Vladi F. 2022. Assessing the relationship between biodiversity conservation and slow food culture in selected protected areas in Albania. Biodiversitas 23: 1319-1326. Information on the knowledge, uses, and abundance of natural resources in protected areas can provide insight into conservation status and strategies in these locations and human attitudes. The slow-food concept is introduced to accommodate agriculture and food production with strong consideration on environment sustainability, biodiversity conservation and social justice. This paper investigates the slow food knowledge, perception, and contribution to nature conservation in Albania's five protected areas. The performed work is based on a field survey and structured questionnaire aiming to link the current stands within slow food, biodiversity conservation and perceptions of the tourism sector in the protected areas. Our integrated analysis found that the coverage of food biodiversity items related to slow food culture that are relevant to prescribed management plans of the protected areas was at the low level from 4-9 out of 17 considered categories. This was directly related to the low level of conservation at the mid-term assessment that varied from 0 to 62% of originally planned ones. The data also confirmed that the visitors were imposed to a situation of readiness for paying extra for the consumption of the locally based product (i.e., in line with slow food concept) within a specific protected area with their response ranging from 0 to 18%. The information can be used towards generating sustainable use and conservation plans that are appropriate for the local communities and protected areas.
Evaluation of Argulus indicus on striped snakehead (Channa striata) in Towuti Lake, South Sulawesi, Indonesia
Authors: Amriana Amriana , Sari Dwi Kesuma , Sriwulan Sriwulan , Anshary Hilal
Published: June 2022

Abstract. Amriana, Sari KD, Sriwulan, Anshary H. 2022. Evaluation of Argulus indicus on striped snakehead (Channa striata) in Towuti Lake, South Sulawesi, Indonesia. Biodiversitas 23: 1355-1362. Fish parasites are frequently present in wild freshwater fish populations, but data are limited on their distribution and impacts. This research aimed to investigate the severity of parasitic Argulus infestation on striped snakeheads (Channa striata) caught in Towuti Lake based on prevalence, intensity, and the bacteria associated with Argulus parasitizing C. striata. The research was conducted from March 2018 to February 2019 at Towuti Lake, South Sulawesi Province, Indonesia. Striped snakehead samples were captured using fish traps and gillnets. Samples of bacteria associated with Argulus were collected from four striped snakeheads (three infested and one non-infested control). Bacteria from Argulus attachment sites were identified through Vitek-2 Compact biochemical tests. Argulus prevalence on striped snakeheads was in the range 73.3-96.7%, with a mean intensity range of 2.18-14.43 and mean abundance 1.67-13.47. Water quality parameters measured in Towuti Lake remained within the Indonesian standards for freshwater fish habitat. The bacteria in striped snakehead mucus comprised two species in control (Staphylococcus xylosus, Pantoea sp.) and seven species in the parasitized fish (Micrococcus luteus, Bacillus mycoides, Acinetobacter baumannii, Sphingomonas paucimobilis, Pantoea sp., Aerococcus viridans, Staphylococcus arlettae). This study found a very high prevalence of striped snakehead infestation with parasitic A. indicus at low to medium intensity levels. The study also showed that A. indicus infestation was accompanied by and likely stimulated pathogenic bacteria, which can cause skin infections in fish. Therefore, A. indicus could be considered a threat to striped snakehead populations in Towuti Lake.
Antimicrobial activity of Streptomyces spp. sponge-associated isolated from Samalona Island of South Sulawesi, Indonesia
Authors: Rante Herlina , Alam Gemini , Usmar Usmar , Zahra Syarifah , Kurniawati Ari , Ali Alimuddin
Published: June 2022

Abstract. Rante H, Alam G, Usmar, Zahra S, Kurniawati A, Ali A. 2022. Antimicrobial activity of Streptomyces spp. sponge-associated isolated from Samalona Island of South Sulawesi, Indonesia. Biodiversitas 23: 1392-1398. The resistance case of infectious diseases increases annually, while the necessity of antibiotics as a drug choice for therapy most important is needed. One of the efforts to overcome these problems is an investigation of new antibiotic sources, namely marine organisms. Actinomycetes are microbes well known as more antibiotic-producing than fungi and bacteria. This study aims to the identification of marine actinomycetes isolated from sponge samples in Samalona Island, South Sulawesi, Indonesia. The antimicrobial activity was evaluated against multi-drug resistant (MDR) Staphylococcus aureus, Escherichia coli, and Candida albicans. Isolation was carried out using SCA (Starch Casein Agar) medium by the pour plate method. The selected isolates were designated as SML10h and SML10a. The isolates SML 10h and SML 10a were recovered from sponges Haliclona sp. and Aplysina sp., respectively. The production of antimicrobial substances was performed by fermentation of isolates in SNB (Starch Nitrate Broth) medium for 14 days. The antimicrobial activity was shown by the ethyl acetate extract with 2 mg/20 ?L concentration against all test microbes. Phylogenetic analysis of the 16S rRNA gene sequences revealed that the similarity of SML 10a was most closely related to Streptomyces geysiriensis (98%).
Increasing the diversity of marigold (Tagetes sp.) by acute and chronic chemical induced mutation of EMS (Ethyl Methane Sulfonate)
Authors: LENAWATY DEWI YANNY , SUKMA DEWI , SYUKUR MUHAMAD , SUPRAPTA DEWA NGURAH , NURCHOLIS WARAS , AISYAH SYARIFAH IIS
Published: June 2022

Abstract. Lenawaty DY, Sukma D, Syukur M, Suprapta DN, Nurcholis W, Aisyah SI. 2022. Increasing the diversity of marigold (Tagetes sp.) by acute and chronic chemical induced mutation of EMS (Ethyl Methane Sulfonate). Biodiversitas 23: 1399-1407. Increasing the diversity of marigold (Tagetes sp.) can be carried out through chemical induction mutations with Ethyl Methane Sulfonate (EMS).This study aims to obtain the LC50value, determine the sensitivity level of plants, and obtain plant diversity of Tagetes sp.with EMS both acutely and chronically. The genetic material used in this study was derived from T. erecta genotype MG04 and T. patula genotype MG21. The acute mutation technique was performed by soaking the seeds in EMS concentration for 4 hours under 10 different concentration levels (0%, 0.2%, 0.4%, 0.6%, 0.8%, 1.0%, 1.5%, 2.0%, and 3.0%). The chronic mutation technique was carried out by diluting the concentration of EMS LC501/10x, 1/100x, 1/1000x and immersion time of 6 hours, 24 hours and 48 hours. The study used a Completely Randomized Block Design. Observationswere made on the percentage of surviving plants, quantitative and qualitative characters. The data obtained were analyzed using Boxplot and ANOVA. The results showed that the LC50 value of T. erecta is 0.82% and LC50of T. patula is 1.87%, which means that the sensitivity level of T. erecta to EMS treatment is quite higher than T. patula. The acute application method shows a relatively low mutation rate and limited diversity of flower types. The chronic application method produced various flower shapes and whiter flower color in T. erectaand T. patula resulting in a redder flower color than the acute application method.