bluuebunny/crossref_metadata_2025 huggingface dataset:
Percepción del alumnado universitario sobre la enseñanza virtual y presencial
Authors: Torres Gastelú Carlos Arturo
Published: August 2024

El objetivo de este estudio fue identificar la percepción del alumnado universitario sobre la enseñanza virtual durante la pandemia y su retorno a la enseñanza en la modalidad presencial. Se trata de un estudio cuantitativo de diseño no experimental, transversal con una muestra no probabilística por conveniencia mediante la aplicación de una encuesta a 434 estudiantes de la Universidad Veracruzana. Los ítems del instrumento atienden las dimensiones de desempeño de los docentes, satisfacción del aprendizaje y rendimiento académico. Para el procesamiento y análisis de los datos se usó el software estadístico SPSS versión 25 mediante la estadística descriptiva e inferencial. Para la comprobación de la hipótesis se corrió la prueba no paramétrica de Wilcoxon, en tanto para establecer la correlación se utilizó la prueba de Pearson. Las percepciones de los estudiantes destacan la preferencia de la modalidad presencial sobre la modalidad virtual. Se detectó que sí hay diferencias significativas en las percepciones de los estudiantes universitarios sobre la enseñanza virtual durante la pandemia y al retorno a la enseñanza presencial. De la misma manera existe correlación positiva y estadísticamente significativa entre las dimensiones desempeño de los docentes, satisfacción del aprendizaje y rendimiento académico.
¿Qué significados de la derivada favorece un profesor en su planeación de clase?
Authors: Briceño  Solís Eduardo Carlos , Hernández Sánchez Judith Alejandra , Morales  de la Cruz Jonathan Adrián
Published: August 2024

El presente artículo reporta un análisis de contenido de las planeaciones didácticas de cuatro profesores sobre la enseñanza de la derivada. El objetivo es indagar cómo estos profesores articulan y organizan los significados de este contenido en sus planeaciones de clase. Se considera como problemática que la enseñanza de la derivada en el nivel medio superior –NMS– presenta significados escolares de manera desarticulada y aislada donde predomina lo algorítmico y simbólico. Como resultado existe una discrepancia entre los significados del programa de estudios y lo que proponen las planeaciones de los profesores.
Análisis cualitativo en la investigación
Authors: Viramontes Anaya Efrén
Published: August 2024

El tema de este ensayo es la sistematización de información para realizar el análisis cualitativo. El objetivo es proponer un sistema simple para analizar datos cualitativos, complementar el proceso con otros elementos de cierre de un trabajo de investigación y convertirlos en resultados y hallazgos que respondan a las preguntas y objetivos de cualquier investigación cualitativa. Se fundamenta con especialistas en metodología de investigación que han propuesto sistemas de análisis de información mediante fases, pasos, etapas o dimensiones. La metodología para el desarrollo del contenido temático de este estudio se centra en un análisis comparativo de diversas de formas de sistematizar datos cualitativos encontrados en la literatura científica sobre el tema referido. La aportación final se concreta en la propuesta sencilla sobre los procedimientos de sistematización de la información cualitativa que responda a cualquier metodología de investigación que requiera este tipo de análisis a través de tres fases: descripción, análisis transversal por categorías y síntesis interpretativa...
Зависимость предельной нагрузки для трехслойной балки интерметаллид-керамика-металл при трёхточечном изгибе от геометрии, модуля упругости и температуры
Authors:   Московский государственный университет им. М.В. Ломоносова, Москва, Россия, Хвостунков К. А. ,   ФГБУН Институт структурной макрокинетики и проблем материаловедения им. А.Г. Мержанова РАН, Великов М.В. ,   Московский государственный университет им. М.В. Ломоносова, Москва, Россия, Бажин П. М. ,   ФГБУН Институт структурной макрокинетики и проблем материаловедения им. А.Г. Мержанова РАН
Published: August 2024

В данной работе исследуется разрушение трёхслойной балки в условиях трёхточечного изгиба. В качестве критерия разрушения выбрано условие превышения максимального допустимого растягивающего напряжения. Для анализа используется линейно-упругая постановка задачи в рамках модели балки Бернулли-Эйлера. В силу формирования диффузионного контакта слоев в процессе СВС-технологии эффекты расслоения не рассматриваются. Выводится зависимость, определяющая предельную допустимую нагрузку для трёхслойной балки, как функцию величины нагрузки, механических и геометрических параметров балки. Полученные результаты были применены к задаче определения оптимальных пропорций слоёв, которые бы обеспечили балке наилучшую прочность на трёхточечный изгиб, при условии, что материалами слоёв выбраны интерметаллид - TiAl, керамика - TiB и металл - Ti, исходя из технологической необходимости с учетом зависимости параметров от температуры. В решении учитывается возможность начала процесса разрушения со среднего или даже верхнего слоя. При соответствующем подборе параметров, когда нейтральная ось попадает на верхний слой, исследована точка равнопрочности. Для данных материалов показано, что причиной разрушения являются слои TiB (средний слой) и Ti (нижний слой) и для максимизации предельной допустимой нагрузки для композитной балки необходимо минимизировать толщину TiAl (верхнего слоя). В качестве примеров рассмотрена зависимость предельной нагрузки от введенных параметров в случае линейных зависимостей от температуры модуля Юнга и пределов прочности на изгиб каждого слоя для таких трехслойных балок как интерметаллид-керамика-металл и керамика-интерметаллид-керамика. Показано изменение влияния на пределньную нагрузку порядкового номера слоя с ростом температуры.
Knowledge Regarding Consent in Medical Practice among the Para-Clinical Medical Students: A Descriptive Cross-Sectional Study
Authors: Dey Mithila , Baidya Chinmoy , Chowdhury Rajib Pal , Barua Ashim Kumar , Kashem Syed Md , Barua Dipsikha
Published: August 2024

Background: Consent means free, valid, voluntary agreement, approval, or permission for compliance with some act. Many doctors get involved in medical negligence during professional practice, probably due to a lack of accurate documentation or consent. Para-clinical medical students are at the initial stages of learning about consent. The present study was conducted to assess the knowledge about consent in medical practice among them.
Materials and methods: A cross-sectional survey was conducted from September 2022 to December 2022 on 200 para-clinical medical students of Chattagram Maa-O-Shishu Hospital Medical College. A self-administered structured questionnaire was used and data were analyzed by SPSS-V.20.
Results: Among the students, the majority were female (63.5%) and Muslim (83.5%). The age range of the participants was 20–24 years. It was found that 97% of the students had knowledge about the various types of consent in rational medical practice. 73.5% were satisfied with their knowledge about consent in medical practice. 91% believed that written consent was the best type of consent in medical practice. Major participants (89%) believed that only a person over 18 years of age with a sound mind could provide valid consent for general physical examinations and procedures. The majority (88%) felt the need of regular CME on consent. Statistically no association was found with knowledge about consent to gender and phase distribution (p>0.05).
Conclusion: This study indicated that the most of the participants were aware of consent and had sufficient knowledge on it. Arranging seminars, workshops and CME would reduce the gap and help in building a constructive attitude toward the necessity of updating knowledge about consent in medical practice.   
IAHS Medical Journal Vol 6(1), June 2023; 25-29
Outcome of Triamcinolone Injection following Optical Internal Urethrotomy in Short Segment Anterior Urethral Stricture
Authors: Ghose Anirban , Monowar Ul Haque Mohammed , Mazumder Md Kamal Uddin , Rahman Md Tanvir , Mohiuddin Mohammad , Chowdhury M K M Foisal Quader
Published: August 2024

Background: Internal Urethrotomy is a surgical procedure to treat urethral stricture disease. To assess the outcome of triamcinolone injection following Optical Internal Urethrotomy (OIU) in short segment anterior urethral stricture in our setting.
Materials and methods: This randomized controlled trial was carried out in the Department of Urology, Chittagong Medical College Hospital, Chattogrm from September 2017 to August 2018 on 60 patients with short segment of anterior urethral stricture. Cases were randomly allocated to group A (OIU with Triamcinolone) and group B (OIU without Triamcinolone). Each group consisted of 26 patients. Data were analyzed and compared by Stata (version 16).
Results: There were no significant differences in the baseline characteristics of the patients. At 9 months of follow up, American Urological Association Symptom Score (AUA score) was decreased in Group A (5.8±4.3) in comparison to control Group B (10.4±7.9). In Group A, Qmax of only 1 patient was < 15 ml/min which was presented at 9 month of the study period. This was considered as recurrence (3.57%). So, success rate of Group A was 96.43% as the Qmax of the 27 patients were > 15ml/min. In Group B, Qmax of the 4 patients (14.81%) were found <15ml/min. Among the 4 patient, 1 patient was presented with near retention at 7 day after surgery and Qmax < 10ml/min and present with complete blind tract in RGU with MCU. He was managed with OIU within my follow up period. So, it was considered as failure (3.3%). But other 3 patients were presented with Qmax <15ml/min, much earlier than Group A and these were considered as recurrence (11.1%). So it can be said that recurrence rate is low and the period of recurrence is also prolonged in those patient who were treated with OIU along with Triamcinolone injection
 Conclusion: OIU with intralesional triamcinolone is better than OIU alone. It significantly reduces and delays the recurrence of anterior urethral stricture.
IAHS Medical Journal Volume 06(1), June 2023; 20-24
Serum Sodium Status in Children with Simple and Complex Febrile Seizure: A Comparative Hospital Based Study
Authors: Shil Sunanda , Datta Mitra , Barua Dazy , Jahan Rifat , Shil Prashanta Kumar , Das Aparup Kanti , Chakraborty Rivu Raj
Published: August 2024

Background: Fever is the most common cause of convulsions, in infancy and childhood. Complex febrile seizures are associated with an increased risk of subsequent epilepsy. The present study aimed to evaluate the role of serum sodium levels and associated factors in children with simple and complex febrile seizures admitted to a tertiary level hospital in Bangladesh.
Materials and methods: Children aged between 6 months to 60 months with febrile seizures, admitted to the Paediatric ward of Chittagong Medical College Hospital, Chattogram, were recruited in the study. Serum sodium level at admission were estimated and patients were categorized into two group: simple and complex febrile seizure. Data were analyzed by comparing different variables between two groups.
Results: A total of 60 children were enrolled in the study in which 36 were diagnosed with simple febrile seizures and 24 of them with complex febrile seizures. The mean age was 22.3 months and there was male preponderance with a male to female ratio of 2.3:1. The mean serum sodium level was 136.9±6.5 mmol/l and 18 (30%) patients had hyponatremia. Serum sodium levels were significantly lower in children with complex febrile seizure (134.0±6.1 and 138.9 ± 6.0, p=0.003) than the children with simple seizure. The optimal cutoff value of serum sodium level was 134 mmol/L with an area under the receiver operating characteristic curve of 0.723 (95% CI: 0.590-0.856), with sensitivity of 80.0% and specificity of 50.0%.
Conclusions: Our study suggested that serum sodium levels were significantly lower in children with complex febrile seizures. However, because of its lower specificity value, further studies are needed to confirm the utility of serum sodium level in childhood febrile seizure.
IAHS Medical Journal Volume 6(1)  June 2023; 34-38
LEARNING OBSTACLE PADA MATERI PERKALIAN DI KELAS IV SDN 19 MAKARTI JAYA
Authors: Ayuningtyas Irena , Fuadiah Nyiayu Fahriza , Surmilasari Nora
Published: August 2024

Penelitian ini bertujuan untuk mengidentifikasi hambatan belajar (learning obstacle) pada materi perkalian yang dapat dilihat melalui tiga aspek yaitu ontogenical obstacle, didactical obstacle dan epstimologi obstacle. Penelitian ini menggunakan metode kualitiatif dan instrument yang berupa tes, wawancara siswa dan guru kelas IV serta didukung dengan menganalisis RPP, analisis bahan ajar buku teks. Subjek penelitian ini adalah siswa kelas IV SD 19 Makarti Jaya yang berjumlah 20 siswa dan satu orang guru kelas. Teknik analisis data yang digunakan ialah kualitatif dengan teknik yang bervariasi. Hasil penelitian ini ditemukan learning obstacle yang dialami siswa yakni kurangnya motivasi dalam belajar, kurangnya kesiapan belajar siswa yang menjadi ontogenical obstacle dan kurangnya metode dan media pembelajaran yang bervariatif yang menjadi didactical obstacle serta kurangnya pemahaman konsep tentang perkalian merupakan pejumlahan yang berulang yang menjadi epstimology obstacle.
Smart watchdog: intelligent virtual checker based on human factors
Authors: Ng Rica Chak Lam , Tam Wai Pan , Lau Ching Yin , Chan Jessica , Ko Wing Fung , Chan Arthur
Published: August 2024

Many operations in the railway rely on manual operations, which means that there are human factors involved. Meanwhile, safety is always the first priority on the railways and is the cornerstone of MTR’s success, particularly during these various manual operations. Although there are many safeguards for addressing human factors, these traditional approaches can be complex, may require huge efforts, or may involve additional human resources to perform the checks and balances. Therefore, an innovative methodology called the Smart Watchdog was explored to automatically monitor the manual operations on display screens through the application of artificial intelligence to the videos captured from the display screens. Through a series of artificial intelligence learning, fine-tuning, and testing processes, Smart Watchdog enables accurate and robust detection of the real-time status available on the display screens and generates respective outputs as timely reminders to safeguard potential wrong manual operations. Four representative use cases in MTR are presented in this paper, which shows the significant improvement after the implementation of Smart Watchdog. With this innovative solution, train services can be enhanced and MTR, being one of the leading railway companies, can evolve to be a smart, safe, and efficient railway company.
Alterations in immunized antigens of Anisakis pegreffii by ampicillin-induced gut microbiome changes in mice
Authors: Kim Myungjun , Choi Jun Ho , Yi Myung-hee , Oh Singeun , Yong Tai-Soon , Kim Ju Yeong
Published: August 2024

The gut microbiome plays an essential role in host immune responses, including allergic reactions. However, commensal gut microbiota is extremely sensitive to antibiotics and excessive usage can cause microbial dysbiosis. Herein, we investigated how changes in the gut microbiome induced by ampicillin affected the production of IgG1 and IgG2a antibodies in mice subsequently exposed to Anisakis pegreffii antigens. Ampicillin treatment caused a notable change in the gut microbiome as shown by changes in both alpha and beta diversity indexes. In a 1-dimensional immunoblot using Anisakis-specific anti-mouse IgG1, a 56-kDa band corresponding to an unnamed Anisakis protein was detected using mass spectrometry analysis only in ampicillin-treated mice. In the Anisakis-specific anti-mouse IgG2a-probed immunoblot, a 70-kDa band corresponding to heat shock protein 70 (HSP70) was only detected in ampicillin-treated and Anisakis-immunized mice. A 2-dimensional immunoblot against Anisakis extract with immunized mouse sera demonstrated altered spot patterns in both groups. Our results showed that ampicillin treatment altered the gut microbiome composition in mice, changing the immunization response to antigens from A. pegreffii. This research could serve as a basis for developing vaccines or allergy immunotherapies against parasitic infections.
Identification of the protease inhibitory domain of Trichinella spiralis novel cystatin (TsCstN)
Authors: Yuthithum Thassanee , Phuphisut Orawan , Reamtong Onrapak , Kosoltanapiwat Nathamon , Chaimon Salisa , Kobpornchai Porntida , Thawornkuno Charin , Malaithong Preeyarat , Sawatdichaikul Orathai , Adisakwattana Poom
Published: August 2024

The Trichinella spiralis novel cystatin (TsCstN) inhibits cathepsin L (CatL) activity and inflammation of macrophages during lipopolysaccharide (LPS) induction. To identify the protease inhibitory region, this study applied an in silico modeling approach to simulate truncation sites of TsCstN (Ts01), which created four truncated forms, including TsCstN∆1-39 (Ts02), TsCstN∆1-71 (Ts03), TsCstN∆1-20, ∆73-117 (Ts04), and TsCstN∆1-20, ∆42-117 (Ts05). The superimposition of these truncates modeled with AlphaFold Colab indicated that their structures were more akin to Ts01 than those modeled with I-TASSER. Moreover, Ts04 exhibited the closest resemblance to the structure of Ts01. The recombinant Ts01 (rTs01) and truncated proteins (rTs02, rTs03, and rTs04) were successfully expressed in a prokaryotic expression system while Ts05 was synthesized, with sizes of approximately 14, 12, 8, 10, and 2.5 kDa, respectively. When determining the inhibition of CatL activity, both rTs01 and rTs04 effectively reduced CatL activity in vitro. Thus, the combination of the α1 and L1 regions may be sufficient to inhibit CatL. This study provides comprehensive insights into TsCstN, particularly regarding its protein function and inhibitory domains against CatL.
Efek Ekstrak Bunga Melati (Jasminum Sambac) dengan Metode Elektrik terhadap Efek Knockdown pada Nyamuk Aedes Aegypti Stadium Dewasa
Authors: Amalia Rizky Noni , Putri Illahika Anung , Musyarrofah Aida , Safithri Fathiyah
Published: August 2024

Abstract. Dengue Hemorrhagic Fever (DHF) is caused by the Dengue virus (DENV) which is transmitted by mosquitoes. One of the factors that cause high number of dengue infections in Indonesia is due to poor vector management. Chemical-based insecticides used to control mosquitos can cause human health problems and mosquito resistance. Jasmine flower (Jasminum sambac) can be used as an alternative because it contains flavonoids, alkaloids, saponins, and tannins that can act as natural insecticides. Objective: Proving the effect of jasmine flower extract (Jasminum sambac) with the electric method has a knockdown effect on adult stage Aedes aegypti mosquitoes. Method: True Experimental Post Test Only Control Group Design. In each test group, 20 adult Aedes aegypti were used with four replications. In this study, the test group consisted of malathion as positive control, aquades as negative control, and jasmine flower extract (Jasminum sambac) at concentrations of 5%, 10%, 15%, 20%, and 25%. Data was analyzed using Kruskal Wallis test, Post Hoc Mann Whitney test, Spearman correlation test and Probit test. Results and Discussion: Kruskal Wallis test obtained a significance value (P) <0.05. Post hoc mann whitney test showed knockdown effect at concentrations of 15%, 20% and 25%. The results of the Spearman correlation test (P = 0.019 and R = 0.440) showed a sufficient correlation between the conÂ­centration of jasmine flower extract and the knockdown effect. LC50 was obtained by probit test at a concentration of 12.839%. The results showed that the content of jasmine flower extract had an insecticidal effect with the electric method. Conclusion: Jasmine flower extract (Jasminum sambac) applied using the electric method has a knockdown effect on adult Aedes aegypti at concentrations of 15%, 20% and 25%.
Pengaruh Ekstrak Buah Labu Siam (Sechium edule) terhadap Ketebalan Dinding Aorta Tikus Putih (Rattus norvegicus strain wistar) Model Aterosklerosis
Authors: Andari Desy , Wiraldi Putra Aulia , Setiawan Meddy
Published: August 2024

Background: Atheroslerosis is a disease that formed due to cumulation of the fibrous tissues in vascular wall and gradually become thrombus. Chayote contains antioxidants such flavonoid, saponin, and ascorbic acid that could prevent the thickening of the vascular wall. Objective: To determine the effect of chayote extract on aortic vascular wall thickness in white rats with atherosclerosis model. Methods: True experimental with post-test only controlled group design. Sixteen white male rats divided into 4 groups: positive control group and 3 treatment groups that given chayote extract at different doses (20 mg/day, 40 mg/day, 80 mg/day). The H&E stained aortic preparate were observed with 400x magnification used optical microscope and vascular thickness were measured with optilab software. Data analized with one way ANOVA, post hoc, pearson and linear regression test. Result: There was significant effect of chayote extract to the aortic arch vascular wall thickness (ANOVA p=0,001) and the dose that started giving effect was 40 mg/day (Post Hoc test). There was very strong, significant, and reciprocally correlation between chayote extract and aortic wall thickness (R=-0,896). Chayote extract affected aortic wall thickness with the value of 80,4%. Conclusion: Chayote extract could prevent the thickening of aortic wall in atherosclerotic rats.
Profil Health-Related Quality of Life (HRQOL) Masyarakat Surabaya
Authors: Perwito Sari Dewi , Suryagama Digdo
Published: August 2024

The development of a nation or state is determined by one of the factors, namely socially and economically productive human resources. Productive human resources are part of the health development plan that has been planned by the Ministry of Health of the Republic of Indonesia through the 2015-2019 Strategic Plan. Improving the quality of human life where health-related quality of life (HRQoL) is part of the main strategic plan. A large and healthy population of productive age supports the wheels of a country's development. Surabaya is one of the metropolitan cities with an estimated productive age population of 75.86% in 2019. This study aims to describe the HRQoL of the people of Surabaya City in 2019. This study is survey research conducted in a descriptive cross-sectional manner using a survey sheet (questionnaire) SF6D in Indonesian version that has been validated. Quality of life assessment is expressed in utility values and analyzed by correlation test and difference test. The results of a survey conducted on 226 people resulted in an average utility score of 0.8945 with an SD of 0.1109. Significant differences can be seen in the utility values of the age, education, and marital status groups (p<0.05). The results of the study concluded that the HRQoL of productive age in Surabaya was good, while the factors of age, education, and status influenced the level of HRQoL
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETIL ASETAT BUAH OKRA HIJAU (Abelmoschus esculentus L.)
Authors: Rahmi Rahmi Muthia , Fatmawati Fatmawati , Hidayatullah M. Hidayatullah , Putri Putri Indah Sayakti , Aditya Aditya Noviadi Rakhmatullah
Published: August 2024

Abstract. Okra fruit (Abelmoschus esculentus L.) is a potential medicinal plant because it contains several compounds such as alkaloids, phenols, flavonoids, steroids and tannins which have anti-diabetic, antioxidant, antimicrobial, antiallergic, antiviral and anti-inflammatory properties. The purpose of this study was to identify the content of flavonoid compounds qualitatively and quantitatively. The extraction method was maceration, used ethyl acetate solvent. Qualitative testing of flavonoid compounds used TLC, 5% AlCl₃ spotting appearance. Quantitative test used UV-Vis Spectrophotometry method, quercetin as comparison, λmaks 415 nm. The TLC results show three stains with each Rf value of 0.76; 0.53; 0.23. The results of determined the total flavonoid content of okra fruit were 4.069 ± 0.211 mg QE/g extract. From the research results obtained, it can be concluded that the ethyl acetate extract of green okra contains flavonoids.
Kata Kunci:
Abelmoschus esculentus L; total flavonoid content; ethyl acetate extract; TLC
Formulasi Lotion dari Ekstrak Buah Bit (Beta vulgaris) dengan Perbedaan Komposisi Asam Stearat
Authors: Fendi Yoga Wardana  , Riska Riska Milani
Published: August 2024

Abstract. Lotion is a skin moisturizing cosmetic preparation that has non-greasy properties and is easily applied to the skin. This study aims to make a lotion formulation from beetroot (Beta vulgaris) extract according to the physical stability properties. In this study, three lotion preparation formulas were made with differences in stearic acid with a composition of 5%, 10% and 15%. Determination of the physical stability of the product is determined according to organoleptic, homogeneity, spreadability, pH and preference tests. The results showed that beetroot extract produced a yield percentage of 8.34%. Phytochemical screening showed that beetroot extract contains flavonoids, tannins, saponins and steroids or triterpenoids. Beetroot extract lotion was evaluated for 16 days. The results of the organoleptic evaluation on lotions F1, F2 and F3 showed no change. In the lotion homogeneity test F1, F2 and F3 produced a homogeneous lotion. Spreadability tests on F1, F2 and F3 had a spreading diameter of 4.5 – 5.5 g.cm/s. The pH test of lotions F1, F2 and F3 produced the same as a pH value of 7. F1 was the most preferred formula because all parameters give good results. Based on this study, it can be concluded that differences in stearic acid concentrations have no effect on the physical quality test of beetroot extract lotion preparations.
Kata Kunci
Buah bit, Lotion, Uji mutu fisik
PENGARUH PEMBERIAN SUSU KEDELAI KUNING (Glycine max (L.) Merr.) TERHADAP KADAR KOLESTEROL TOTAL PADA PRIA HIPERKOLESTEROLEMIA
Authors: Santi Widiasari  , Mutiara Mutiara Muslimah , Eliya Mursyida
Published: August 2024

Abstract.Hypercholesterolemia is an increase in blood cholesterol levels, which is more than 200 mg / dl. In Indonesia, 9.3% of the incidence of hypercholesterolemia is in productive age, namely the age range of 25-40 years. One of the drugs for hypercholesterolemic sufferers is a statin which is believed to reduce LDL levels and inhibit the formation of cholesterol by indirectly affecting cholesterol levels in the blood. Soybeans are known to reduce cholesterol levels because they contain isoflavones that bind to the endoplasmic reticulum, then increase the Low-density lipoprotein (LDL) receptors in the liver. So that LDL levels in plasma are measured to be low. Objective: To analyze the effect of giving soy milk on cholesterol levels in hypercholesterolemic men. Method: Experimental using the design "One-Group Pretest-Postest Design". The sample consisted of 10 men with hypercholesterolemia given 250 ml / day for 2 weeks. Results: The results showed a significant value of p <0.05. The average total cholesterol level in the provision of soy milk decreased by 6.2 mg / dl. Conclusion: The provision of soy milk has an effect on total cholesterol levels in hypercholesterolemic men.
Kata Kunci
antibakteri; Hiperkolesterolemia, kolesterol, susu kedelai
OPTIMASI MORINGA GUM DAN POLIVINIL ALKOHOL DALAM SEDIAAN MUCOADHESIVE BUCCAL FILM DILTIAZEM HIDROKLORIDA
Authors: Nani Sukmawati  , Lusia Oktora Ruma Kumala Sari  , Eka Deddy Irawan
Published: August 2024

Abstract. Diltiazem Hydrochloride (HCl) is commonly used in hypertension therapy for its beneficial effects, such as reducing blood vessel pressure resistance and relaxing the heart muscles. In an in-vivo study, Diltiazem HCl is known to be decrease by 60% of its bioavailability due to first-pass metabolism. Thus, it is necessary to develop a new administration route, some of which is buccal drug delivery route in mucoadhesive buccal film. Moringa gum is a polyuronide polymer with a hydroxyl group in its side chains, giving the potential use as a mucoadhesive polymer. However, it has poor folding endurance and its release kinetics study has not been investigated. Polyvinyl alcohol (PVA) is a water-soluble polymer with hydroxyl side chain. PVA is known for its high tensile strength and flexibility, though it can be affected by humidity. The aim of this research is to determine the right amount of moringa gum and PVA to obtain a film with good physical characteristics and mucoadhesive residence time. In this study, the optimization of moringa gum and PVA was carried out using factorial design. Mucoadhesive buccal film was prepared by solvent casting method, the films were later evaluated and the obtained responses were analyzed by Software Design Expert 11.0.0. The optimization result shows the film containing the amount of moringa gum 2% and PVA 5% can produce the optimum formula. The mucoadhesive buccal film formula has surface pH of 6.083, mucoadhesive residence time of 445.055 min, swelling index of 4.067, and 87.9913% drug release in in-vitro drug release study after 420 min following the Higuchi model release kinetics. Therefore, it can be concluded that the obtained optimum formula of mucoadhesive buccal film can be used in the preparation of mucoadhesive buccal film Diltiazem HCl..
Kata Kunci:
 Hypertension; Diltiazem HCl; Mucoadhesive buccal film; Moringa gum; PVA.
Pengendalian Tindakan Phubbing Anak: Studi Analisis Peran Orang Tua Dalam Pola Asuh Anak Sekolah Dasar
Authors: Hidayat Wahyu
Published: August 2024

The purpose of this study is to explain the importance of the role of parents in controlling children's phubbing actions, as well as familiarizing children in using smartphones wisely. This type of research is field research with  descriptive approach. The subjects in this study included parents who had early childhood and elementary school with a total of 12 people (5 Male, 7 Female). There are two data collection techniques conducted by researchers, namely (1) observation techniques, (2) interviews. Data testing techniques to verify the validity of data in this study include extension of participation, persistence of observation, and triangulation of methods. The results of the research showed that parents complain about the lack of communication with their children when their children use gadgets and many children do not care about their parents' calls when using gadgets. Solutions to research problems, the role of parents in supervising and accompanying children in the use of gadgets, as follows: 1) parents need to set a time limit when using technology to work or enjoy entertainment, and do not violate it, 2) parents accompany the child when using gadgets, 3) balance smartphone users with other activities, such as playing outdoors, 4) set smartphone rules (length of use and visible content), 5) parents as suri tauladan their children, as well as explaining content that should not be seen and accessed.
Peran Kepala Madrasah Dalam Penguatan Pengembangan Keprofesian Berkelanjutan (PKB) Kelompok Kerja Guru 016 Kecamatan Gringsing Kabupaten Batang
Authors: Musfuji’atun Siti , Untung Slamet , Rohman Taufiqur
Published: August 2024

This study aims to analyze the implementation of the Continuing Professional Development (PKB) program in the Teacher Working Group 016, Gringsing District, Batang Regency in 2023; to analyze the role of the madrasah head in supporting the implementation of the Continuing Professional Development (CPD) program in Teacher Working Group 016, Gringsing District, Regency in 2023. This study uses qualitative research with a type of phenomenology. The research subjects were in four MI, namely MI Islamiyah Yosorejo 01, MI Islamiyah Yosorejo 02, MI Islamiyah Kebondalem 01, and MI Islamiyah Kebondalem 02. Data collection techniques used interviews, observation, and documentation. The data analysis technique uses the Miles and Huberman model which consists of data condensation, data presentation, and data verification. The results of the research show that the Continuing Professional Development Program (CPD) in Teacher Working Group 016, Gringsing District, Batang Regency in 2023 consists of self-development programs, scientific publications, and innovative work programs which can be categorized as low. Some of the obstacles found included inflexible time, lack of knowledge, lack of outreach, lack of mentoring and guidance, etc.; The role of the madrasa head in supporting the implementation of the Continuing Professional Development (CPD) program in Teacher Working Group 016, Gringsing District, Batang Regency in 2023 includes the roles of educator, manager, administrator, supervisor, leader, innovator, and motivator.
Analisis Permasalahan Calistung Pada Siswa Kelas III SD Muhammadiyah Birrul Walidain
Authors: Imamuddin Ahmad Ridlwan , Kurniawan Bagas , Riswari Lovika Ardana
Published: August 2024

This study aims to analyze calistung problems in third-grade students of SD Muhammadiyah Birrul Walidain. This research is a type of descriptive qualitative research that seeks an in-depth understanding of natural social phenomena. The data collection technique used is purposive sampling technique through interview methods, documentation, and direct observation. Based on the data obtained from the results of the study, it shows that out of 26 students in the class, there is one male student named Bima Aditya who still has difficulty in reading, writing, and counting due to a lack of learning experience at home, less innovative learning from teachers and lack of attention from parents and teachers to improve calistung skills in children. Therefore, teachers are required to be able to find innovations in learning strategies and implement differentiated learning to understand and differentiate students' learning styles from one another.
Al-Jam’u Wa Al-Taufiq dan Naskh dalam Penyelesaian Kontradiksi Hukum Islam
Authors: Oktiviana Nindia
Published: August 2024

In this modern era, the development of the science of fiqh is very rapid. This, of course, has a correlation with the understanding of the arguments originating from the Al-Qur'an and Hadith. For example, there is a legal argument that is faced with a certain problem that will find a solution, but there are also several laws that originate from the Al-Qur'an in the same context, which actually cause different thoughts in understanding it. Therefore, when there are contradictory arguments, there are several methods to solve them. However, this paper will explain the method of solving it by means of Al-Jam'u Wa Al-Taufiq and Naskh. When there are contradictory arguments, then the solution is to collect and compromise them, so it is called Al-Jam'u Wal Al-Taufiq. Whereas when there are contradictory arguments then it is resolved by strengthening or exceeding one of the arguments from other conflicting arguments so that it can be known which argument is stronger, it is called the tarjih method.
Upaya Meningkatkan Kualitas Membaca Al-Qur’an Siswa Kelas Tiga SD Negeri Sitirejo dengan Metode Pembiasaan
Authors: Mutoharoh Siti , Fatimah Siti , Faisal Faisal
Published: August 2024

This study aims to determine the efforts to improve the quality of students' reading the Qur'an. The method used is Classroom Action Research by going through the stages of planning, implementing, observing and reflecting. The data is taken based on the results of interviews, observations, and tests. The subjects were 16 grade 3 students of SD Negeri Sitirejo. The results of the study can be concluded that the use of the habituation method of reading the Qur'an and discussion of tajwid can improve the quality of students' reading of the Qur'an, because in each cycle of meetings there is an increase in the percentage of results.
Sumber Belajar Internet di Pesantren
Authors: Putri Rizkika
Published: August 2024

This article explains how the internet is a learning resource in Islamic boarding schools. This article aims to explain the benefits and negative impacts of the internet as well as solutions for handling them in Islamic boarding schools. Islamic boarding schools have several criteria based on the number of students, based on facilities and infrastructure, and in terms of what is taught. The negative impacts of using the internet as a learning resource are explained in this article, namely; (1) the availability of access to pornographic sites which are feared to damage the morals of the students, (2) then there are entertainment facilities created by the internet, such as online games and social networking sites which can give the students a taste of addiction.
Etika dan Tanggung Jawab dalam Menguatkan Kesalehan Sosial di Bulan Ramadhan dalam Kegiatan Bersedekah
Authors: Supriyanti Tuti , Sanusi Anwar
Published: August 2024

Social piety is a collective responsibility, where we all play a role in fostering goodness both for ourselves and our surroundings. Individual piety is often referred to as habluminallah, while social piety is known as habluminannas. Piety is usually associated with religion, namely people who are devout in practicing religious teachings. One highly recommended good deed in Islam is giving alms, especially during the month of Ramadan, in addition to observing the fast. Muslims are encouraged to increase their good deeds, such as giving alms, during this holy month. Responsibility is inherent, meaning it is a natural part of human life; everyone inevitably has responsibilities. If someone neglects their responsibilities, others will compel them to fulfill them. Therefore, responsibility can be viewed from two sides: the side of the doer and the side of the interest of others. This article aims to strengthen social piety in the community, particularly through giving alms during Ramadan. The method used is a literature review. In conclusion, social piety can be naturally achieved in conjunction with the performance of maghdhah and ammah worship, as these acts of worship encompass all aspects of human behavior.
HASHIMOTO DISEASE IN 7 YEARS OLD CHILD
Authors:   Widya Mandala Catholic University / Lewoleba Regional Hospital, Sunardi Wenny , Beyeng Rosalia Theodosia Dateng ,   Pediatrician, Lewoleba Regional Hospital, Siwi Putu Ianta Parama ,   Resident Doctor in Paediatrics, Udayana University
Published: August 2024

Hashimoto thyroiditis (AIT) is a common cause of hypothyroidism that can occur in childhood and adolescence (ages six to sixteen years) and often occurs in women. AIT can be determined by increases in TSH with normal thyroid hormone serum levels. The diagnosis of AIT based on clinical symptoms of hypothyroid, biochemical results, and ultrasound images. Treatment is carried out by administering levothyroxine at an initial dose of 1 – 2 g/weight/day. This case report aims to show that AIT can show a wide range of symptoms and effects from the treatment that given to patient.
CORRELATION BETWEEN HOUSEWIVES PREPAREDNESS IN FACING FLOOD WITH COPING MECHANISM IN TAMPING HAMLET, GRESIK REGENCY, INDONESIA
Authors:   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Wijono Steven , Sincihu Yudhiakuari ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Young Andre ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Djoka Marlyn ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Soegeng Kevin K ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Yusup David R ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Hartono Felicia P ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Faustina Danica ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Agusalim Yonathan ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University, Pangestu Vennessa M ,   Departement of Public Health, Medical Faculty, Widya Mandala Surabaya Catholic University
Published: August 2024

BACKGROUND: Indonesia is the largest archipelagic country in the world across the equator, located between two continents, two oceans, and located between three plates of the earth. This condition causes the risk of natural disasters such as floods. Tamping is a hamlet that often experiences flooding in Gresik Regency caused by the overflow of the Lamong tributary. This causes disruption in various sectors, especially the economy in the village, causing stress. AIM: Researchers want to know whether there is a correlation between community preparedness and coping mechanisms in dealing with floods. METHODS: The research design used was observational analytic with a cross sectional research design. In this study, the sample size was 59 people who were housewives in Tamping hamlet. The research data was taken through a questionnaire. RESULTS: Based on the results of data analysis using Spearman's test regarding the preparedness of housewives with coping mechanisms, the value of r=0.502 and significance value of p=0.001. CONCLUSION: There is a relationship between the preparedness of housewives in dealing with floods and coping mechanisms in Tamping Hemlet.
Disease assessment in ‘coral gardening’ nurseries in the Maldives and implications for coral restoration success
Authors: Dehnert I , Galli P , Siena F , Montano S
Published: August 2024

Coral diseases are an increasing threat to continuously degrading reefs as disease abundance and virulence are expected to increase in the future. Active conservation measures, specifically coral restoration projects, are increasingly being implemented worldwide. Yet little is known about the implications of disease occurrence in a restoration context. This study describes white syndrome pathogenesis in 2 coral genera, farmed in 2 mid-water rope nurseries located in a reef and a lagoon habitat in the Maldives. Over a 112 d monitoring period, disease metrics were obtained from 336 Pocillopora and 96 Acropora fragments to assess the impacts of unmitigated disease progression in coral nurseries. Disease had low prevalence (2.2%) and incidence (0.007) in reef-farmed Pocillopora, but survival (91%) was significantly reduced in comparison with the unaffected lagoon-farmed Pocillopora (99%). In contrast, lagoon-farmed Acropora showed high disease prevalence (78.5%) and incidence (0.064), and a lower survival (79%) than disease-unaffected reef-farmed Acropora (98%). These findings had distinct implications for coral gardening success. While Pocillopora was considered suitable for outplanting, especially since subsequent mitigation interventions were successful, the diseased, lagoon-reared Acropora posed a potential risk to the restoration site and was unsuitable for outplanting following 1 yr of farming effort. Our findings demonstrate that unmitigated diseases can cause major setbacks to restoration success. Coral gardening projects are likely to be particularly susceptible; therefore, disease monitoring and risk management are imperative. Since there is currently a lack of available diagnostic and mitigative tools, this study aims to provide case study data for restoration practitioners.
Hector’s dolphin distribution at Kaikōura before and after a major earthquake
Authors: Ellis GK , Weir J , Bräger S , Heinrich S
Published: August 2024

Catastrophic natural events can have major impacts on marine ecosystems, but effects on mobile predators, such as cetaceans, remain poorly understood. This study investigated whether the coastal distribution patterns of Hector’s dolphins Cephalorhynchus hectori hectori off Kaikōura, New Zealand, changed after the powerful Kaikōura earthquake in November 2016. Dolphin sightings from boat-based surveys conducted before (2013-2016) and after (2016-2020) the earthquake were binned into 18 sectors of 4 km length each. The dolphins’ occurrence across sectors was then compared during pre- and post-earthquake periods using generalised linear models. Areas of high and low occurrence probability were temporally stable for Hector’s dolphins from before to 1.5 yr post-quake. Historic sighting data (from the 1990s) matched with the observed high-occurrence areas, indicating decadal stability in distribution patterns. An increase in dolphin occurrence was noted in the final 2-4 yr post-quake period across most nearshore sectors. This was particularly noticeable in the historically low-use areas along the narrow shelf at the head of the deep Kaikōura Canyon. This observation could indicate increased population connectivity between dolphins using the northern and southern sections of the Kaikōura Peninsula. The dolphins’ occurrence patterns pre-quake at the sector level were broadly explained by water depth, distance to rivers, sea surface temperature and chlorophyll when explored with generalised additive models. We discuss scenarios that may explain the species’ persistent distribution patterns during natural perturbation events as well as synergies with other conservation measures.
The Effort of Improving Grammar Mastery Through Wordwall Unjumble Sentence
Authors: Yudhawati Haliza Tri , Iffah Ida Farhatul , Putri Intan Cahyani , Melyana Mita , Almanar Muhammad Abduh
Published: August 2024

Teaching grammar should be enjoyable to inspire students to achieve better results. Teachers need to recognize that today's students are digital natives who are adept at utilizing technology for learning enhancement. This research aims to explore how the use of the unjumble sentence feature on Wordwall can improve students’ grammar mastery. Classroom action research was employed in this study. The subjects of this research were five students, which consisted of two males and three females, aged between 13-15 years. The instruments used in this research were observation and test. After the implementation of Wordwall in Cycle 1, The findings indicated that initially, 60% of students met the Minimum Criteria of Mastery in Cycle 1, which increased to 80% in Cycle 2. The findings demonstrate that Wordwall unjumble sentence significantly enhanced grammar mastery by making learning more interactive and engaging.
PENERAPAN MODEL PEMBELAJARAN E-LEARING DI ERA DIGITALISASI GUNA MENINGKATKAN MINAT BELAJAR SISWA
Authors: Khopipah Siti Khopipah
Published: August 2024

Penggunaan teknologi dalam proses pembelajaran memiliki peran penting dalam meningkatkan kualitas pendidikan, sehingga pembelajaran yang diselenggarakan menjadi lebih efektif dan efisien. Oleh karena itu, dengan adanya teknologi diharapkan dapat menciptakan susana pembelajaran yang menstimulasi peserta didik dalam mengeksplorasi serta menggali potensi dirinya secara maksimal. Adanya pembelajaran abad 21 yang melibatkan teknologi informasi dan komunikasi dalam kegiatan pendidikan, menjadikan e-learning sebagai salah satu hal yang penting dalam untuk menunjang terlaksanakannya pembelajaran yang melibatkan teknologi digital guna meningkatkan minat belajar siswa. Penelitian ini bertujuan untuk meningkatkan minat belajar siswa melalui model pembelajaran E-Learning pada era digitalisasi. Metode penelitian yang digunakan merupakan metode penelitian kualitatif dengan pendekatan deskriptif yang dilakukan dengan kegiatan wawancara untuk menggali informasi yang dilakukan selama 3 hari. Adapun subjek dalam penelitian ini tingkat SMK. Hasil penelitian menjelaskan bahwa penggunaan e-learnig dalam kegiatan pembelajaran cukup efektif digunakan dalam meningkat minat belajar siswa, namun karena pengunaanya kurang familiar maka masih terdapat beberapa siswa yang kurang tertarik terhadap pembelajaran berbasis e-learning.
Kata kunci: E-learninng, Minat Belajar