bluuebunny/crossref_metadata_2025 huggingface dataset:
The Predatory Myxobacterium Citreicoccus inhibens gen. nov. sp. nov. Showed Antifungal Activity and Bacteriolytic Property against Phytopathogens
Authors: Zhou Yang , Yi Shuoxing , Zang Yi , Yao Qing , Zhu Honghui
Published: October 2021

The application and promotion of biological control agents are limited because of poor efficacy and unstable performance in the field. Screening microorganisms with high antagonistic activity, effective adaptability, and high field-survival should be prospected. Myxobacteria are soil predatory bacteria with wide adaptability, which are considered as good antagonists. Here, we report a myxobacterium strain M34 isolated from subtropical forest soil in South China using the Escherichia coli baiting method. Based on the morphological observation, physiological test, biochemical characteristics, 16S rRNA gene sequence, and genomic data, strain M34 was identified as a novel genus and novel species, representing a new clade of Myxococcaceae, for which the name Citreicoccus inhibens gen. nov. sp. nov. is proposed (type strain M34T = GDMCC 1.2275T = KCTC 82453T). The typical features of M34, including fruiting body formation and extracellular fibrillar interconnection, indicated by microscopic observations, contributed to cell adaption in different environments. Furthermore, the strain showed antifungal activity against phytopathogenic fungi and predatory activity to both Gram-negative and Gram-positive phytopathogenic bacteria. The bioprotective mechanisms are attributed to the presence of pyrrolnitrin and derivative with antifungal activity and the extracellular proteins with lytic activity against pathogenic bacteria. Due to its multiple beneficial traits, strain M34 has the potential to be developed into a versatile biocontrol agent for the management of both fungal and bacterial phytopathogens.
Structures, Electronic Properties and Carrier Transport Mechanisms of Si Nano-Crystalline Embedded in the Amorphous SiC Films with Various Si/C Ratios
Authors: Shan Dan , Sun Daoyuan , Tang Mingjun , Yang Ruihong , Kang Guangzhen , Tao Tao , Cao Yunqing
Published: October 2021

Recent investigations of fundamental electronic properties (especially the carrier transport mechanisms) of Si nanocrystal embedded in the amorphous SiC films are highly desired in order to further develop their applications in nano-electronic and optoelectronic devices. Here, Boron-doped Si nanocrystals embedded in the amorphous SiC films were prepared by thermal annealing of Boron-doped amorphous Si-rich SiC films with various Si/C ratios. Carrier transport properties in combination with microstructural characteristics were investigated via temperature dependence Hall effect measurements. It should be pointed out that Hall mobilities, carrier concentrations as well as conductivities in films were increased with Si/C ratio, which could be reached to the maximum of 7.2 cm2/V∙s, 4.6 × 1019 cm−3 and 87.5 S∙cm−1, respectively. Notably, different kinds of carrier transport behaviors, such as Mott variable-range hopping, multiple phonon hopping, percolation hopping and thermally activation conduction that play an important role in the transport process, were identified within different temperature ranges (10 K~400 K) in the films of different Si/C ratio. The changes from Mott variable-range hopping process to thermally activation conduction process with temperature were observed and discussed in detail.
Mechanism, Material, Design, and Implementation Principle of Two-Dimensional Material Photodetectors
Authors: Yang Cheng , Wang Guangcan , Liu Maomao , Yao Fei , Li Huamin
Published: October 2021

Two-dimensional (2D) materials may play an important role in future photodetectors due to their natural atom-thin body thickness, unique quantum confinement, and excellent electronic and photoelectric properties. Semimetallic graphene, semiconductor black phosphorus, and transition metal dichalcogenides possess flexible and adjustable bandgaps, which correspond to a wide interaction spectrum ranging from ultraviolet to terahertz. Nevertheless, their absorbance is relatively low, and it is difficult for a single material to cover a wide spectrum. Therefore, the combination of phototransistors based on 2D hybrid structures with other material platforms, such as quantum dots, organic materials, or plasma nanostructures, exhibit ultra-sensitive and broadband optical detection capabilities that cannot be ascribed to the individual constituents of the assembly. This article provides a comprehensive and systematic review of the recent research progress of 2D material photodetectors. First, the fundamental detection mechanism and key metrics of the 2D material photodetectors are introduced. Then, the latest developments in 2D material photodetectors are reviewed based on the strategies of photocurrent enhancement. Finally, a design and implementation principle for high-performance 2D material photodetectors is provided, together with the current challenges and future outlooks.
Ketogenic Diet for Cancer: Critical Assessment and Research Recommendations
Authors: Lane Jordin , Brown Nashira I. , Williams Shanquela , Plaisance Eric P. , Fontaine Kevin R.
Published: October 2021

Despite remarkable improvements in screening, diagnosis, and targeted therapies, cancer remains the second leading cause of death in the United States. It is increasingly clear that diet and lifestyle practices play a substantial role in cancer development and progression. As such, various dietary compositions have been proposed for reducing cancer risk and as potential adjuvant therapies. In this article, we critically assess the preclinical and human trials on the effects of the ketogenic diet (KD, i.e., high-fat, moderate-to-low protein, and very-low carbohydrate content) for cancer-related outcomes. The mechanisms underlying the hypothesized effects of KD, most notably the Warburg Effect, suggest that restricting carbohydrate content may impede cancer development and progression via several pathways (e.g., tumor metabolism, gene expression). Overall, although preclinical studies suggest that KD has antitumor effects, prolongs survival, and prevents cancer development, human clinical trials are equivocal. Because of the lack of high-quality clinical trials, the effects of KD on cancer and as an adjunctive therapy are essentially unknown. We propose a set of research recommendations for clinical studies examining the effects of KD on cancer development and progression.
Astaxanthin Inhibits Diabetes-Triggered Periodontal Destruction, Ameliorates Oxidative Complications in STZ-Injected Mice, and Recovers Nrf2-Dependent Antioxidant System
Authors: Bhattarai Govinda , So Han-Sol , Kieu Thi Thu Trang , Kook Sung-Ho , Lee Jeong-Chae , Jeon Young-Mi
Published: October 2021

Numerous studies highlight that astaxanthin (ASTX) ameliorates hyperglycemic condition and hyperglycemia-associated chronic complications. While periodontitis and periodontic tissue degradation are also triggered under chronic hyperglycemia, the roles of ASTX on diabetes-associated periodontal destruction and the related mechanisms therein are not yet fully understood. Here, we explored the impacts of supplemental ASTX on periodontal destruction and systemic complications in type I diabetic mice. To induce diabetes, C57BL/6 mice received a single intraperitoneal injection of streptozotocin (STZ; 150 mg/kg), and the hyperglycemic mice were orally administered with ASTX (12.5 mg/kg) (STZ+ASTX group) or vehicle only (STZ group) daily for 60 days. Supplemental ASTX did not improve hyperglycemic condition, but ameliorated excessive water and feed consumptions and lethality in STZ-induced diabetic mice. Compared with the non-diabetic and STZ+ASTX groups, the STZ group exhibited severe periodontal destruction. Oral gavage with ASTX inhibited osteoclastic formation and the expression of receptor activator of nuclear factor (NF)-κB ligand, 8-OHdG, γ-H2AX, cyclooxygenase 2, and interleukin-1β in the periodontium of STZ-injected mice. Supplemental ASTX not only increased the levels of nuclear factor erythroid 2-related factor 2 (Nrf2) and osteogenic transcription factors in the periodontium, but also recovered circulating lymphocytes and endogenous antioxidant enzyme activity in the blood of STZ-injected mice. Furthermore, the addition of ASTX blocked advanced glycation end products-induced oxidative stress and growth inhibition in human-derived periodontal ligament cells by upregulating the Nrf2 pathway. Together, our results suggest that ASTX does not directly improve hyperglycemia, but ameliorates hyperglycemia-triggered periodontal destruction and oxidative systemic complications in type I diabetes.
Interactions between Indigenous Endophyte Bacillus subtilis L1-21 and Nutrients inside Citrus in Reducing Huanglongbing Pathogen Candidatus Liberibacter Asiaticus
Authors: Asad Suhail , He Pengbo , He Pengfei , Li Yongmei , Wu Yixin , Ahmed Ayesha , Wang Yunyue , Munir Shahzad , He Yueqiu
Published: October 2021

Huanglongbing (HLB) pathogen Candidatus Liberibacter asiaticus (CLas) brings a great concern about the phloem nutrient transport in diseased plants. There is an urgent need to find the best management strategies to reduce the losses in the citrus industry worldwide. Endophytic bacteria are negatively affected by CLas pathogen, and these endophytes are associated with improved availability of nutrients and pathogen resistance. This study underpins the relationship between CLas pathogen, endophyte population and nutrients availability in citrus plants. The citrus plants were treated with Bacillus subtilis L1-21 and Hoagland solution to find out synergism efficacy to mitigate citrus HLB. We showed that citrus shoots in the presence of 50% Hoagland solution displayed maximum number of endophytes with 6.28 × 103 to 3.04 × 105 CFU/g. Among 50 candidate strains, B. subtilis L1-21 emerged as potential antagonist against surrogate strain Xanthomonas citri subsp. citri. The citrus half-leaf method identified that application of endophyte L1-21 with 50% Hoagland solution successfully reduces the CLas abundance. We point out that this combination results in a higher number of endophytes population with 2.52 × 104 to 9.11 × 106 CFU/g after 60 days, and reduces CLas pathogen abundance in asymptomatic HLB plants. In HLB symptomatic citrus plants, B. subtilis L1-21 potentially increases the endophyte population from 1.11 × 104 to 5.26 × 107 CFU/g in the presence of Hoagland solution, and pathogen abundance was reduced from 9.51 × 105 to 1.06 × 104 copies/g. Altogether, we suggested that the presence of endophyte L1-21 with Hoagland solution is more effective in HLB asymptomatic citrus plants, but a slight reduction of pathogen was observed in symptomatic plants. The findings revealed the role of indigenous citrus endophyte B. subtilis L1-21 along with other nutrients in the reduction of CLas pathogen abundance inside symptomatic and asymptomatic plants in citrus endophyte–nutrient–pathogen interplay.
Biocontrol of Soil-Borne Pathogens of Solanum lycopersicum L. and Daucus carota L. by Plant Growth-Promoting Actinomycetes: In Vitro and In Planta Antagonistic Activity
Authors: Djebaili Rihab , Pellegrini Marika , Ercole Claudia , Farda Beatrice , Kitouni Mahmoud , Del Gallo Maddalena
Published: October 2021

Biotic stress caused by pathogenic microorganisms leads to damage in crops. Tomato and carrot are among the most important vegetables cultivated worldwide. These plants are attacked by several pathogens, affecting their growth and productivity. Fourteen plant growth-promoting actinomycetes (PGPA) were screened for their in vitro biocontrol activity against Solanum lycopersicum and Daucus carota microbial phytopathogens. Their antifungal activity was evaluated against Fusarium oxysporum f. sp. radicis-lycopersici (FORL) and Rhizoctonia solani (RHS). Antibacterial activity was evaluated against Pseudomonas syringae, Pseudomonas corrugata, Pseudomonas syringae pv. actinidiae, and Pectobacterium carotovorum subsp. carotovorum. Strains that showed good in vitro results were further investigated in vitro (cell-free supernatants activity, scanning electron microscope observations of fungal inhibition). The consortium of the most active PGPA was then utilized as biocontrol agents in planta experiments on S. lycopersicum and D. carota. The Streptomyces albidoflavus H12 and Nocardiopsis aegyptica H14 strains showed the best in vitro biocontrol activities. The diffusible and volatile compounds and cell-free supernatants of these strains showed both antifungal (in vitro inhibition up to 85%, hyphal desegregation and fungicidal properties) and antibacterial activity (in vitro inhibition >25 mm and bactericidal properties). Their consortium was also able to counteract the infection symptoms of microbial phytopathogens during in planta experiments, improving plant status. The results obtained highlight the efficacy of the selected actinomycetes strains as biocontrol agents of S. lycopersicum and D. carota.
Human Polyomaviruses (HPyV) in Wastewater and Environmental Samples from the Lisbon Metropolitan Area: Detection and Genetic Characterization of Viral Structural Protein-Coding Sequences
Authors: Condez Ana Carolina , Nunes Mónica , Filipa-Silva Andreia , Leonardo Inês , Parreira Ricardo
Published: October 2021

Due to the lack of reliable epidemiological information regarding the geographic distribution and genetic diversity of human polyomaviruses (HPyV) in Portugal, we addressed these issues in this initial study by focusing on the Lisbon Metropolitan area, the most populated and culturally diverse hub in the country. The HPyV structural protein-coding sequence was partially amplified using two touch-down PCR multiplex protocols, starting from water samples, collected between 2018 and 2020, where viral genomes were detected. The obtained results disclosed the frequent detection of HPyV1, HPyV2, HPyV5, and HPyV6 in 35.3% (n = 6), 29.4% (n = 5), 47.1% (n = 8) and 29.4% (n = 5), respectively, of the water samples analyzed. The sequences assigned to a given viral species did not segregate to a single genotype, this being especially true for HPyV2 for which five genotypes (including a putative new genotype 9) could be identified. The phylogenetic trees obtained for HPyV5 and HPyV6 had less resolving power than those obtained for HPyV1/HPyV2, but both viruses were shown to be genetically diverse. This analysis emphasizes the epidemiological helpfulness of these detection/genetic characterization studies in addition to being relevant tools for assessment of human waste contamination.
Biological Control of Plant Diseases: An Evolutionary and Eco-Economic Consideration
Authors: He Dun-Chun , He Meng-Han , Amalin Divina M. , Liu Wei , Alvindia Dionisio G. , Zhan Jiasui
Published: October 2021

Biological control is considered as a promising alternative to pesticide and plant resistance to manage plant diseases, but a better understanding of the interaction of its natural and societal functions is necessary for its endorsement. The introduction of biological control agents (BCAs) alters the interaction among plants, pathogens, and environments, leading to biological and physical cascades that influence pathogen fitness, plant health, and ecological function. These interrelationships generate a landscape of tradeoffs among natural and social functions of biological control, and a comprehensive evaluation of its benefits and costs across social and farmer perspectives is required to ensure the sustainable development and deployment of the approach. Consequently, there should be a shift of disease control philosophy from a single concept that only concerns crop productivity to a multifaceted concept concerning crop productivity, ecological function, social acceptability, and economical accessibility. To achieve these goals, attempts should make to develop “green” BCAs used dynamically and synthetically with other disease control approaches in an integrated disease management scheme, and evolutionary biologists should play an increasing role in formulating the strategies. Governments and the public should also play a role in the development and implementation of biological control strategies supporting positive externality.
Growth Inhibition of Triple-Negative Breast Cancer: The Role of Spatiotemporal Delivery of Neoadjuvant Doxorubicin and Cisplatin
Authors: Salerno Dominick , Sofou Stavroula
Published: October 2021

Combinations of platinum-based compounds with doxorubicin in free and/or in liposomal form for improved safety are currently being evaluated in the neoadjuvant setting on patients with advanced triple-negative breast cancer (TNBC). However, TNBC may likely be driven by chemotherapy-resistant cells. Additionally, established TNBC tumors may also exhibit diffusion-limited transport, resulting in heterogeneous intratumoral delivery of the administered therapeutics; this limits therapeutic efficacy in vivo. We studied TNBC cells with variable chemosensitivities, in the absence (on monolayers) and presence (in 3D multicellular spheroids) of transport barriers; we compared the combined killing effect of free doxorubicin and free cisplatin to the killing effect (1) of conventional liposomal forms of the two chemotherapeutics, and (2) of tumor-responsive lipid nanoparticles (NP), specifically engineered to result in more uniform spatiotemporal microdistributions of the agents within solid tumors. This was enabled by the NP properties of interstitial release, cell binding/internalization, and/or adhesion to the tumors’ extracellular matrix. The synergistic cell kill by combinations of the agents (in all forms), compared to the killing effect of each agent alone, was validated on monolayers of cells. Especially for spheroids formed by cells exhibiting resistance to doxorubicin combination treatments with both agents in free and/or in tumor-responsive NP-forms were comparably effective; we not only observed greater inhibition of outgrowth compared to the single agent(s) but also compared to the conventional liposome forms of the combined agents. We correlated this finding to more uniform spatiotemporal microdistributions of agents by the tumor-responsive NP. Our study shows that combinations of NP with properties specifically optimized to improve the spatiotemporal uniformity of the delivery of their corresponding therapeutic cargo can improve treatment efficacy while keeping favorable safety profiles.
AEGIS, the Virtual European Genebank: Why It Is Such a Good Idea, Why It Is Not Working and How It Could Be Improved
Authors: Hintum Theo van , Engels Johannes M. M. , Maggioni Lorenzo
Published: October 2021

Europe is very active in terms of conserving plant genetic resources, with hundreds of genebanks and thousands of dedicated people involved. However, the resulting infrastructure is, along with being very expensive, far from efficient and not very reliable. In this opinion paper, the authors describe how this situation arose, and why the European Cooperative Programme for Plant Genetic Resources (ECPGR), the collaborative umbrella organization of the European countries involved, has not been able to improve this situation so far significantly. The principles of the decentralized virtual genebank (AEGIS) are described, and an analysis is made of the reasons for its lack of success. Possible changes for making AEGIS a success, or at least steps in the right direction, are proposed. These changes center around the creation of a system of certified genebanks with proper quality management, guaranteeing the long-term conservation of, and immediate access to the plant genetic resources conserved in it.
Temperature/Reduction Dual Response Nanogel Is Formed by In Situ Stereocomplexation of Poly (Lactic Acid)
Authors: Gao Wenli , Wang Zhidan , Song Fei , Fu Yu , Wu Qingrong , Liu Shouxin
Published: October 2021

A novel type of dual responsive nanogels was synthesized by physical crosslinking of polylactic acid stereocomplexation: temperature and reduction dual stimulation responsive gels were formed in situ by mixing equal amounts of PLA (Poly (Lactic Acid)) enantiomeric graft copolymer micellar solution; the properties of double stimulation response make it more targeted in the field of drug release. The structural composition of the gels was studied by proton nuclear magnetic resonance (1H NMR) and Fourier transform infrared spectroscopy (FT-IR). Using transmission electron microscope (TEM) and dynamic light scattering (DLS) instruments, the differences in morphology and particle size were analyzed (indicating that nanogels have dual stimulus responses of temperature sensitivity and reduction). The Wide-Angle X-ray diffractionr (WAXD) was used to prove the stereocomplexation of PLA in the gels, the mechanical properties and gelation process of the gels were studied by rheology test. The physically cross-linked gel network generated by the self-recombination of micelles and then stereo-complexation has a more stable structure. The results show that the micelle properties, swelling properties and rheological properties of nanogels can be changed by adjusting the degree of polymerization of polylactic acid. In addition, it provides a safe and practical new method for preparing stable temperature/reduction response physical cross-linked gel.
Terahertz Imaging for Paper Handling of Legacy Documents
Authors: Zhai Min , Locquet Alexandre , Citrin David S.
Published: October 2021

Despite predictions of the paperless office, global demand for printing and writing paper remains strong, and paper appears to be here to stay for some time. Not only firms, but also governments, libraries, and archives are in possession of large collections of legacy documents that still must be sorted and scanned. In this study, terahertz-based techniques are demonstrated to address several routine tasks related to the automated paper handling of unsorted legacy documents. Specifically, we demonstrate terahertz-based counting of the number of sheets in unconsolidated paper stacks, as well as locating stapled documents buried in paper stacks.
Personality Classification of Social Users Based on Feature Fusion
Authors: Wang Xiujuan , Sui Yi , Zheng Kangfeng , Shi Yutong , Cao Siwei
Published: October 2021

Based on the openness and accessibility of user data, personality recognition is widely used in personalized recommendation, intelligent medicine, natural language processing, and so on. Existing approaches usually adopt a single deep learning mechanism to extract personality information from user data, which leads to semantic loss to some extent. In addition, researchers encode scattered user posts in a sequential or hierarchical manner, ignoring the connection between posts and the unequal value of different posts to classification tasks. We propose a hierarchical hybrid model based on a self-attention mechanism, namely HMAttn-ECBiL, to fully excavate deep semantic information horizontally and vertically. Multiple modules composed of convolutional neural network and bi-directional long short-term memory encode different types of personality representations in a hierarchical and partitioned manner, which pays attention to the contribution of different words in posts and different posts to personality information and captures the dependencies between scattered posts. Moreover, the addition of a word embedding module effectively makes up for the original semantics filtered by a deep neural network. We verified the hybrid model on the MyPersonality dataset. The experimental results showed that the classification performance of the hybrid model exceeds the different model architectures and baseline models, and the average accuracy reached 72.01%.
Fusion Method to Estimate Heart Rate from Facial Videos Based on RPPG and RBCG
Authors: Lee Hyunwoo , Cho Ayoung , Whang Mincheol
Published: October 2021

Remote sensing of vital signs has been developed to improve the measurement environment by using a camera without a skin-contact sensor. The camera-based method is based on two concepts, namely color and motion. The color-based method, remote photoplethysmography (RPPG), measures the color variation of the face generated by reflectance of blood, whereas the motion-based method, remote ballistocardiography (RBCG), measures the subtle motion of the head generated by heartbeat. The main challenge of remote sensing is overcoming the noise of illumination variance and motion artifacts. The studies on remote sensing have focused on the blind source separation (BSS) method for RGB colors or motions of multiple facial points to overcome the noise. However, they have still been limited in their real-world applications. This study hypothesized that BSS-based combining of colors and the motions can improve the accuracy and feasibility of remote sensing in daily life. Thus, this study proposed a fusion method to estimate heart rate based on RPPG and RBCG by the BSS methods such as ensemble averaging (EA), principal component analysis (PCA), and independent component analysis (ICA). The proposed method was verified by comparing it with previous RPPG and RBCG from three datasets according to illumination variance and motion artifacts. The three main contributions of this study are as follows: (1) the proposed method based on RPPG and RBCG improved the remote sensing with the benefits of each measurement; (2) the proposed method was demonstrated by comparing it with previous methods; and (3) the proposed method was tested in various measurement conditions for more practical applications.
Accuracy Tests and Precision Assessment of Localizing Underground Utilities Using GPR Detection
Authors: Karsznia Krzysztof Ryszard , Onyszko Klaudia , Borkowska Sylwia
Published: October 2021

Applying georadar (GPR) technology for detecting underground utilities is an important element of the comprehensive assessment of the location and ground infrastructure status. These works are usually connected with the conducted investment processes or serialised inventory of underground fittings. The detection of infrastructure is also crucial in implementing the BIM technology, 3D cadastre, and planned network modernization works. GPR detection accuracy depends on the type of equipment used, the selected detection method, and external factors. The multitude of techniques used for localizing underground utilities and constantly growing accuracy demands resulting from the fact that it is often necessary to detect infrastructure under challenging conditions of dense urban development leads to the need to improve the existing technologies. The factor that motivated us to start research on assessing the precision and accuracy of ground penetrating radar detection was the need to ensure the appropriate accuracy, precision, and reliability of detecting underground utilities versus different methods and analyses. The results of the multi-variant GPR were subjected to statistical testing. Various analyses were also conducted, depending on the detection method and on the current soil parameters using a unique sensor probe. When planning detection routes, we took into account regular, established grids and tracked the trajectory of movement of the equipment using GNSS receivers (internal and external ones). Moreover, a specialist probe was used to evaluate the potential influence of the changing soil conditions on the obtained detection results. Our tests were conducted in a developed area for ten months. The results confirmed a strong correlation between the obtained accuracy and the measurement method used, while the correlation with the other factors discussed here was significantly weaker.
Geochemical Analysis of Two Samples of Bitumen from Jars Discovered on Muhut and Masirah Islands (Oman)
Authors: Connan Jacques , H. Engel Michael , Jackson Robert B. , Priestman Seth , Vosmer Tom , Zumberge Alex
Published: October 2021

Two samples of bitumen were obtained, one from a torpedo jar (c. 3rd–8th C. AD) from Masirah island and one from a Tunisian jar (c. 18th C. AD) from Muhut island off the central coast of Oman. Steranes and terpanes, as well as isotope data on chromatographic fractions, were used as tools to characterize the bitumen. Comparison of data with those already acquired on bitumen from torpedo jars from Thailand, Iran, Indonesia, Sri Lanka, Saudi Arabia, India, and oil seeps from Iran and Iraq allowed us to conclude that the bitumen originated from different areas of southwest Iran. Those of the Muhut jar were likely from Khuzistan, whereas those from Masirah island appear to have been sourced from Kermanshah. These findings are in keeping with other similar geochemical studies undertaken on bitumen lined vessels from across the region (see more below).
The Decision-Making Analysis on End-of-Life Vehicle Recycling and Remanufacturing under Extended Producer Responsibility Policy
Authors: Khan Syed Abdul Rehman , Godil Danish Iqbal , Thomas George , Tanveer Muhammad , Zia-ul-haq Hafiz Muhammad , Mahmood Haider
Published: October 2021

This research develops a dual-cycle ELV recycling and remanufacturing system to better understand and improve the efficiency of the ELV recycling and remanufacturing businesses. For the flawless operation of this system, the researchers employed evolutionary game theory to establish a game model between original vehicle manufacturers (OVMs) and third-party recyclers with the government involved. This research presents evolutionary stable strategies (ESS) that could promote an ELV recycling and remanufacturing system. Results show that OVMs’ expected profit difference between choosing and not choosing authorization is crucial in their ESS. The licensing fee plays a part of OVMs’ expected profit difference. Based on the results, optimal ESS could be achieved when the OVMs’ expected profit difference between choosing authorization and not choosing authorization and the third-party recyclers’ profit when paying the licensing fee are both positive. Then, the two groups’ involvement in dual-cycle ELV recycling and the remanufacturing system can be ensured. This research implicates the government to devise appropriate reward and punishment strategy to encourage OVMs and third-party recyclers to collaborate for efficient recycling and remanufacturing systems. Particularly, the government is suggested to impose strict restrictions on OVMs to carry ELV recycling and provide support to promote recycling quantity standards. Hence, the ELV recycling and remanufacturing system would be strengthened, thus improving waste management which is crucial for both environmental and resource efficiency.
A Model for the Economic Evaluation of Cultural Ecosystem Services: The Recreational Hunting Function in the Agroforestry Territories of Tuscany (Italy)
Authors: Fagarazzi Claudio , Sergiacomi Carlotta , Stefanini Federico M. , Marone Enrico
Published: October 2021

Cultural ecosystem services (CESs) are non-material benefits generated by natural and human ecosystems that substantially contribute to human wellbeing. Estimating the monetary value of CESs is challenging because there is no real market for these services and therefore there is no actual market price. This study seeks to define an economic evaluation method for these services, with special reference to a recreational CES that has so far received little discussion: hunting. We conducted an online survey in the province of Siena (Tuscany, Italy). The Consumer Surplus estimate of hunters was made using the travel-cost method with a detailed analysis of the annual expenditure on hunting activities, and a negative binomial statistical regression. The results reflect the nature of hunting activity and show the dynamics that have occurred over recent decades. In fact, whereas hunting used to be strongly connected to the rural world as it was an income supplement for local communities, nowadays it has turned into an elitist and almost exclusively recreational activity. In any case, knowing the economic value of ecosystem services constitutes an essential background for planning effective land management and development policies in the short and long term.
Controversy over the Use of “Shade Covers” to Avoid Water Evaporation in Water Reservoirs
Authors: Martínez-Espinosa Rosa María
Published: October 2021

Water scarcity and sustainability are main current concerns affecting billions of people worldwide. Apart from policies designed to guarantee water supply, technologies and procedures have been developed to optimize the uses of water and water recycling as well as to minimize water scarcity. Among these technologies, those based on the use of bioinspired fibres, membranes, nanomaterials, liquid-liquid extraction methods using ionic liquids or approaches involving plants or microbes have been successfully carried out. One of the main problems associated with most of these technologies is the high cost of their implementation and maintenance. Consequently, other cheaper strategies have been explored, such as the use of shade covers. The objective of this work is to summarize the most recent findings on the use of shade covers (suspended shade cloth covers and shade objects) on water reservoirs, mainly agricultural water reservoirs (AWRs). Reflections on the investment-benefit relationship of this technological proposal are also herein discussed. Apart from traditional shade cloth clover, more recently, other covers like shade balls/squares/hexagons (shady objects) have also been proposed as promising approaches to save water and keep its quality. However, the manufacturing of shady objects, mainly made of polyethylene plastic, results in: (i) high cost (high energy cost and use of raw materials like crude oil and natural gas); (ii) significant production of residues, and (iii) visual environmental pollution. The main conclusion reached from this review is that the controversy over the use of shade covers continues in the spotlight of scientists, water managers, and related companies; although this approach saves water and prevents water quality deterioration, a large number of recalcitrant residues are produced, not only during their production, but also when they must be replaced due to deterioration.
Effects of Aquatic Plants on Nutrient Concentration in Water and Growth Performance of Fantail Goldfish in an Aquaculture System
Authors: Roslan Mohd Naqib Azfar Mohd , Estim Abentin , Venmathi Maran Balu Alagar , Mustafa Saleem
Published: October 2021

The effects of two aquatic plants, duckweed (Lemna sp.) and azolla (Azolla sp.), on the growth performance of fantail goldfish (Carassius auratus) and dissolved nutrient concentrations were studied. The experiments were carried out in triplicate sets over a period of seven weeks. Eight specimens of fantail goldfish (length = 5.16 ± 0.06 cm; body weight = 2.30 ± 0.06 g) were released into each of the aquariums containing 40 L of water. Submerged sponge filters were used as the substrate (bed) for the nitrifying bacteria to facilitate nitrification. The fish were provided feed at the rate of 2% of their body weight twice daily. In situ and ex situ water parameters (temperature, dissolved oxygen, pH, total suspended solids, ammonia, nitrite, nitrate, and phosphate), body weight and length of the Fantail goldfish, and wet weight of aquatic plants were measured weekly. The results showed no significant differences (p > 0.05) in any of the three aquariums in water temperature, pH, and dissolved oxygen. Survival of the fish was 100%. The highest food conversion ratio and specific growth rate were observed in the aquarium stocked with duckweed, followed by the aquarium with azolla and the control set (p < 0.05). The concentrations of nutrients (ammonia and nitrate) were recorded lowest (p < 0.05) in the aquarium with azolla, followed by duckweed and the control. The results suggested that aquatic plants were effective in absorbing nutrients and can serve as biofilters to create better conditions for the growth of the fantail goldfish.
Towards Accessibility and Inclusion of Native Mobile Applications Available for Ecuador in Google Play Store
Authors: Acosta-Vargas Patricia , Zarate-Estrella Sebastian , Mantilla-Vaca Franccesca , Novillo-Villegas Sylvia , Chimbo Christian , Luján-Mora Sergio
Published: October 2021

This article aims to evaluate the level of compliance with the accessibility requirements of the most popular native Android mobile applications, for which a sample of 50 Google Play Store applications available in Ecuador was taken. A five-phase method using the Accessibility Scanner tool was used to evaluate the apps. The results revealed that 47.5% are related to problems with tactile orientation, followed by the labeling of elements with 28.2%, and text contrast with 9.2%. The highest number of barriers found in the evaluation of mobile applications corresponds to the principle of operability with 53.9%. This study reveals that, although social networks are widely used, they have 28.7% of accessibility problems. Basing accessibility analysis exclusively on an automatic tool is very limited since it neither detects all errors nor are the errors they detect accurate. However, we suggest complementing the automatic review evaluations with a manual method based on heuristics to ensure an adequate level of accessibility in mobile apps. In addition, we recommend using this study as a starting point to create a software tool using WCAG 2.1 based on artificial intelligence algorithms to help developers evaluate accessibility in mobile apps.
Is gallstone disease a “disease of well-being”?
Authors: Skvortsov Vsevolod Vladimirovich
Published: October 2021

Gallstone disease (choledocholithiasis) is a pathological condition in which stones are formed in the gallbladder. It is caused by a change in the chemical composition of bile with an increase in the concentration of cholesterol in it, hypomotility of the gallbladder, and a number of metabolic disorders. This disease is widespread throughout the world: according to literary sources, about 10% of the population suffers from it. The lowest prevalence of cholelithiasis is noted in the countries of Africa and Asia, which is associated with dietary habits and the absence of high-calorie foods in the diet. In the structure of the overall morbidity, cholelithiasis ranks third after lesions of the cardiovascular system and diabetes mellitus, and exacerbations of cholelithiasis are one of the main reasons for hospitalization with acute surgical pathology. As a rule, women get sick 3-4 times more often than men. If the conservative treatment is ineffective, surgical intervention is necessary; at the present stage, minimally invasive methods with the use of laparoscopic techniques are becoming increasingly popular. To increase the effectiveness of the endoscopic method of treatment, various methods of contact biliary lithotripsy - laser, mechanical, electrohydraulic [2] - are often used.
The effect of the combined application of a low-intensity infrared laser and normobaric hypoxia on the clinical picture of chronic generalized periodontitis
Authors: Dzgoeva Ilona Vasilievna , Remizova Anna Aleksandrovna , Frolkov Valeriy Konstantinovich , Nagornev Sergey Nikolaevich
Published: October 2021

Chronic generalized periodontitis still occupies a leading position among dental diseases, but the effectiveness of drug therapy is insufficient. One of the promising methods of non-drug treatment is the use of factors of various physical nature, which allows to have a therapeutic effect on various functional systems. The combined use of normobaric hypoxia and a low-energy infrared laser significantly increases the effectiveness of complex treatment of patients with chronic generalized periodontitis. At the same time, the regression of clinical signs of the disease was noted to a greater extent when using laser radiation compared to hypoxic exposure. Taking into account the fundamentally different mechanisms of realization of the biological potential of a low-energy infrared laser and normobaric hypoxia, it can be assumed that the increase in the effectiveness of treatment of patients with chronic generalized periodontitis is due to the additive or potentiating nature of the therapeutic effect when they are combined.
Difficulties of Moscow customers in the implementation of electronic execution of small contracts
Authors: Klinkova E.B. , Zatsarinnaya E.I.
Published: October 2021

The standard documentation will soon cover all the most massive purchases published in the EAIST. The standardized documentation used by the metropolitan customers creates clear, convenient and transparent working conditions for the customer and the supplier. The authorities of the city are confident that timely payments are guaranteed on both sides of the procurement: increased transparency will reduce the cases of suppliers failing to meet the terms and conditions of contracts and timely payments from the budget. In the real endeavor faced by the contracts of the City of Moscow after the mandatory electronic workflow in the execution of small volume contracts.
The Low Carb Program for people with type 2 diabetes and pre-diabetes: a mixed methods feasibility study of signposting from general practice
Authors: Scott Emma , Shehata Mishkat , Panesar Arjun , Summers Charlotte , Dale Jeremy
Published: October 2021

Background

Evidence shows type 2 diabetes mellitus (T2DM) can be effectively treated with a reduced-carbohydrate diet to support weight loss. Digital apps are increasingly used to support weight loss, yet little is known about their use as part of general practice diabetes care.

Aim

Determine the feasibility of signposting from routine NHS general practice to a digital weight management tool (Low Carb Program) for patients with T2DM and pre-diabetes.

Design & setting

Mixed-methods feasibility study implemented within routine general practice consultations at four practices in the Midlands, England.

Method

General practices offered signposting to eligible patients attending consultations of any type during a 4-week recruitment period. Rates of offering and accepting signposting were recorded, with program registration, program completion, and self-reported health outcomes (weight, haemoglobin A1C [HbA1c]).

Results

Signposting was offered to 351 patients; 160 (45.6%) accepted, 103 (29.3%) registered with the intervention and 43 (26.9% of patients accepting signposting) completed the programme. GPs reported that signposting added between 1–4 minutes to the consultation length. Patients completing the programme reported greater weight loss (7.2kg versus 1.6kg,P<0.001) and HbA1c improvements (-9.1mmol/mol versus 1.7mmol/mol,P<0.001) compared to those who did not, and were more likely to reduce the number of prescribed diabetes medications in general practice.

Conclusions

Signposting from real-world general practice to theLow CarbProgramis feasible and can potentially improve diabetes outcomes. Further research should explore whether the process of signposting can be enhanced to increase registration, identify whether additional practice-led support leads to increased programme completion, and confirm the intervention’s clinical and cost-effectiveness.
How can communication to GPs at hospital discharge be improved? A systems approach
Authors: Boddy Nicholas , Barclay Stephen , Bashford Tom , Clarkson P John
Published: October 2021

Background

Poor communication to GPs at hospital discharge threatens patient safety and continuity of care, with reliance on discharge summaries that are commonly written by the most junior doctors. Previous quality improvement efforts have largely focused on adherence to standardised templates, with limited success. A lack of understanding has been identified as a cause of the issue’s resistance to decades of improvement work.

Aim

To understand the system of communication to GPs at hospital discharge, with a view to identifying potential routes to improvement.

Design & setting

A qualitative exploration of the secondary-to-primary care communication system surrounding a large UK hospital.

Method

A systems approach, recently defined for the healthcare domain, was used to structure and thematically analyse interviews (n= 18) of clinical and administrative staff from both sides of the primary–secondary care interface, and a subsequent focus group.

Results

The largely one-way communication system structure and the low level of hospital stakeholder insight into recipient GP needs emerged as consistent hindrances to system performance. More open lines of communication and shared records might enable greater collaboration to share feedback and resolve informational deficits. Teaching sessions and assessments for medical students and junior doctors led by GPs could help to instil the importance of detail and nuance when using standardised communication templates.

Conclusion

Facilitating the sharing of performance insights between stakeholder groups emerged as the key theme of how communication might be improved. The empirical measures proposed have the potential to mitigate the safety risks of key barriers to performance such as patient complexity.
STUDY OF DEFORMATION PROPERTIES OF COMPOSITES WITH A HYBRID MATRIX BY THE METHOD OF DYNAMIC AND MECHANICAL ANALYSIS
Authors: Kosenko E.
Published: October 2021

Polymer and composite materials (PCMs) are widely used in various industries for production of small but complex parts and large-sized body parts subjected to significant loads. The production of more critical parts from PCM has led to the need to develop new compositions, structures and technologies for molding composites. The manufacturing technology of PCMs with a hybrid matrix is presented, one of the components of which retains its "liquid" state after the molding of the products, and the second is completely solid. In the resulting composite, the “liquid” components form an independent phase and together with the main binder material, the PCMs represent a hybrid matrix. The results of dynamic mechanical analysis (DMA) of basalt plastics with hybrid matrices, in which the composition of the “liquid” component are anaerobic technical wax and organosilicon polymer materials, are presented. DMA is performed on samples of two types: № 1 - samples with a low content of "liquid" components in the matrix and № 2 - samples with a high content of "liquid" components in the matrix. According to the results of the tests carried out, the best characteristics among PCMs with various types of hybrid matrices are possessed by samples with an organosilicon polymer material in the matrix
Les coronaviroses aviaires
Authors: Brugère-Picoux Jeanne , Bouzouaia Moncef
Published: October 2021

Les coronavirus sont des virus à ARN classés en Alphacoronavirus, Betacoronavirus, Gammacoronavirus et Deltacoronavirus. Ces virus semblent provenir des chauves-souris, et plus particulièrement les Alphacoronavirus et les Betacoronavirus (genre où l’on observe des zoonoses) alors que les oiseaux seraient à l’origine des Gammacoronavirus et des Deltacoronavirus. Le premier coronavirus identifié fut celui de la bronchite infectieuse aviaire en 1931 aux États-Unis. D’autres coronavirus ont été identifiés chez les oiseaux, proches ou différents du virus BI de la bronchite infectieuse aviaire et sont responsables de l’entérite de la dinde (TCoV) et de la maladie foudroyante de la pintade (GfCoV). Enfin, un deltacoronavirus peut être rencontré à la fois chez le porc (PD CoV UKU15) et les oiseaux.