bluuebunny/crossref_metadata_2025 huggingface dataset:
Identifikasi Karakteritik Penebalan dan Jarak Antar-circuli pada Sisik Ikan Wader Bitik (Barbodes binotatus)
Authors: As'ari Hasyim , Kholisah Siti , Syukrya Vhita , Imamah Nur , Agustin Erina
Published: January 2025

Sisik ikan umumnya berfungsi sebgai pelindung tubuh, mendukung pergerakan dan adaptasi lingkungan, juga dapat digunakan dalam identifikasi jenis ikan. Penelitian yang dilakukan difokuskan untuk mengidentifikasi karakteristik sisik pada ikan wader bitik (Barbodes binotatus), dengan  untuk mengidentifikasi karakteritik permukaan sisik, serta mengetahui penebalan dan jarak antar circuli. Penelitian dilakukan dengan pengamatan langsung pada preparat basah pada sisik bagian dorsal, ventral, dan posterior (caudal) secara mikroskopik dengan perbesaran 40X dan 100X, dan dilakukan pemfotoan dengan skala ukur. Pengamatan  penebalan dan jarak antar circuli  dengan menggumakan aplikasi ImageJ versi 13.0.6. Hasil penelitian menunjukkan Bagian dosral dijumpai fokus dengan bentuk seperti sarang lebah, bagian ventral berbentuk seperti titik pusat bergranula, sedangkan bagian posterior tidak dijumpai fokus, namun terdapat garis celah lateral. Penebalan pada circuli rata-rata berkisar 60,81 μm, sedangkan jarak antar-circuli rata-rata dengan panjang 28,41 μm pada bagian ventral, 31,58 μm bagian posterior (caudal), dan 34,35 μm pada bagian dorsal. Kesimpulan penelitian adalah bentuk sisik B. binotatus yang ditemukan berbentuk square, oblonga, dan round, dengan rata-rata penebalan circuli  60,81 μm, dan jarak antar-circuli pada sisik bagian dorssal, ventral, serta posterior (caudal) antara 28,41-34,35 μm.
Keanekaragaman Jenis Capung (Ordo Odonata) di Bendungan Katulampa dan Sekitarnya, Kota Bogor, Jawa Barat
Authors: Kurnia Insan , Lantang Muhammad Ammar Gema , Prayogo Erik , Rijal Maulki Fahru , Ferdian Muhammad Habyeb
Published: January 2025

Capung merupakan serangga yang erat hubungannya dengan ekosistem perairan baik pada fase nimfa maupun dewasa.  Bendungan Katulampa Kota Bogor merupakan bagian Sungai Ciliwung yang dibangun sejak Jaman Belanda.  Penelitian mengenai capung belum pernah dilakukan di ekosistem ini, sehingga penelitian ini bertujuan untuk mengidentifikasi keanekaragamn jenis capung di Bendungan Katulampa dan Sekitarnya.  Penelitian dilaksanakan pada bulan Januari 2023 di empat habitat akuatik dan delapan habitat terestrial dengan metode transek berukuran panjang 100 meter dan lebar 20 meter.  Data dianalisis dengan indeks keanekaragaman jenis (H’) dan indeks kemerataan (E).  Kondisi suhu udara berkisar antara 23-33 oC dan kelembaban udara berkisar antara 54-100%.  Jenis capung yang ditemukan 15 jenis tersebar di seluruh tipe habitat.  Jenis capung paling banyak dijumpai di Aliran Sungai Kalibaru Timur (sembilan jenis), sementara paling sedikit dijumpai di kebun pisang (satu jenis).  Capung jarum hanya ditemukan di habitat akuatik.  Orthetrum sabina dapat dijumpai di seluruh habitat.  Tiga jenis capung dapat dijumpai pada habitat terestrial maupun habitat akuatik, yaitu Orthetrum sabina, O. testaceum, dan Pantala flavescens. Nilai H’ berkisar antara 0,00-2,05 dan nilai E berkisar antara 0,00-,93.  Habitat Aliran Sungai Kalibaru Timur mendapatkan nilai H’ tertinggi (2,05) dan nilai E tertinggi (0,93).
Iktiofauna Sungai Perkotaan Kalilo Pengantigan Banyuwangi
Authors: Ardiyansyah Fuad , Tristi Indah Dwi Kurnia  , Siti Rohmawati
Published: January 2025

Sungai Kalilo merupakan aliran sungai perkotaan dimana kualitas airnya mengalami mengalami tekanan akibat aktivitas manusia. Sampai saat ini belum pernah dilakukan kajian tentang iktiofauna pada aliran sungai Kalilo Banyuwangi. Tujuan dari penelitian ini untuk mengkaji komposisi ikan air tawar di sungai Kalilo Banyuwangi. Penelitian ini dilakukan di bulan Juli 2023 dengan menentukan tujuh titik sampling pengamatan. Metode yang digunakan menggunakan purposive sampling dengan memilih sampel secara sengaja berdasarkan karakteristik tertentu. Didapatkan tiga spesies dengan jumlah total 35 individu. Tiga spesies tersebut diantaranya Barbodes binotatus, Rasbora lateristriata, dan Oxyeleotris urophthalmus. Jumlah individu terbanyak didapatkan dari jenis Barbodes binotatus 31 individu (88%), sedangkan jumlah individu paling sedikit dari spesies Rasbora lateristriata 3 inividu (3%) dan Oxyeleotris urophthalmus 1 individu (3%). Di tinjau dari status IUCN (International Union for Conservation of Nature) tiga spesies tersebut dikelompokkan menjadi tiga kriteria LC, VU, DD. Least Concern (LC) dari spesies Barbodes binotatus, Rentan Vulnerable (VU) dari spesies Rasbora lateristriata, kurang informasi Data Deficient (DD) dari spesies Oxyeleotris urophthalmus.
Uji Efektivitas Ekoenzim Berbahan Dasar Limbah Kulit Pisang Kepok Manado (Musa paradisiaca var. formatypica) Muda Sebagai Antimikroba
Authors: Annisa Zahwa Salsabila  , Rochmah Agustrina  , Achmad Arifiyanto  , Sumardi  , Dwijo Asih Saputri
Published: January 2025

Ekoenzim merupakan larutan fermentasi yang diproduksi menggunakan limbah organik seperti limbah sayur dan kulit buah yang direndam dalam air bersama sama dengan kandungan gula. Salah satu limbah organik yang dapat dimanfaatkan untuk membuat  ekoenzim yaitu limbah kulit pisang. Penelitian ini bertujuan untuk mengetahui efektivitas larutan ekoenzim berbahan organik kulit pisang kepok manado muda. Penelitian eksperimen dilakukan untuk menguji berupa karakter biologi  yaitu aktivitas antimikroba yang dilakukan digunakan Rancangan Acak Kelompok (RAK) satu faktor. Faktor perlakuan adalah pertama konsentrasi ekoenzim yaitu 25%, 50% dan 75% yang diujikan pada Xanthomonas campestris dan Bacillus sp. Setiap unit perlakuan diulang sebanyak 4 kali. Penelitian observasi dilakukan untuk mengetahui karakter kimia larutan ekoenzim antara lain pH, TS, TDS dan kandungan senyawa fitokimia. Hasil yang diperoleh adalah larutan ekoenzim berbahan organik kulit pisang kapok manado muda memiliki  pH 4,0 - 5,5, nilai TS dan TDS masing masing 79% dan 3760 ppm, mengandung senyawa flavonoid, tanin dan saponin.  Uji antibakteri menunjukkan bahwa larutan ekoenzim dengan konsentrasi 50% dan 75% terbukti efektif dalam menghambat pertumbuhan bakteri Bacillus sp. dan Xanthomonas campestris.
Study on the influence of different types of e-sports participation on the improvement of psychological anti-pressure ability of contemporary college students
Authors: Cheng Bingqian , Bayasgalan Zagdkhorol
Published: January 2025

In recent years, e-sports, as an emerging form of competition, has been rapidly integrated into the daily life of college students, and with its rich interactivity, instant feedback and teamwork, e-sports provides them with an effective channel for emotional catharsis and psychological regulation. This study takes students from four universities as the survey object and adopts quantitative research method to analyze the relationship between different types of e-sports activities and psychological stress resistance through questionnaire survey method combined with spss. The samples were randomly sampled, and a total of 500 valid questionnaires were collected. The results of the study show that: 1. In terms of participation, the ability of students to withstand academic stress and life stress is significantly improved, and e-sports is an effective way to regulate emotions and relieve stress; 2. the three types of games (First-person Shooter, Multiplayer Online Battle Arena, Real-Time Strategy Game) have different impacts on stress tolerance, of which FPS has the greatest impact on stress tolerance; 3. the frequency of playing e-sports affects your stress tolerance; 4. teamwork and strategy play an important role in e-sports resilience.
Health-Related apps: Lifestyle application usability questionnaire (LAUQ)
Authors: Keller Veronika , Ercsey Ida , Printz-Markó Erzsébet
Published: January 2025

Adult obesity is a significant health problem, with nearly a quarter of Hungarian citizens aged 15 years and older being obese in 2019 (KSH, 2019a). The use of mobile devices for health purposes is increasing, and many m-health apps target weight-related behaviours. This study uniquely examines the effectiveness and user satisfaction of health-oriented apps among Hungarian adults, with a focus on health improvement. Using a mixed-methods approach, the study identifies six key determinants of health improvement and refines measurement tools by modifying existing parameters and introducing new constructs. The principal objective was to develop a measurement instrument for the usability of nutrition, relaxation and health promotion applications. The research comprised three phases: (1) qualitative content analysis of 13 app reviews conducted in June 2022; (2) focus group interviews involving 32 students from the fields of business, economics and health management; and (3) an online survey (n = 348 users) conducted in December 2023 that included Strava (105 users), Yazio (109 users) and Calm (134 users). Six factors were identified as determinants of health improvement: physical activity, diet, weight loss, general well-being, progress, and body knowledge. The LAUQ (Lifestyle Application Usability Questionnaire) scale was validated, including ‘ease of use’ (5 items), ‘interface and satisfaction’ (7 items) and ‘modified usefulness and effectiveness’ (9 items), with modifications based on qualitative findings. This research offers valuable insights into the factors influencing health improvement and user satisfaction with healthy lifestyle-oriented applications. It also contributes to the refinement of measurement tools such as the LAUQ, which will inform future studies in health psychology, digital health, and behavioural economics.
The role of digital economy engagement in enhancing the performance of local SMEs: An examination of digital adoption and government support
Authors: Misron Aervina , Bawazir Abdullah Abdulaziz , Belhaj Fozi Ali , Saifuddin Syed Gaddafi Syed , Hashim Syukor , Nordin Jonaina , Bayahya Wedyan Y.
Published: January 2025

This study explores the impact of digital economy engagement and digital adoption on the entrepreneurship performance of Small and Medium Enterprises (SMEs) in Malaysia, with a specific focus on the PG Mall platform. Through an analysis of SMEs’ involvement in digital activities such as e-commerce, digital marketing, and data analytics, the research identifies key factors that enhance business performance. The main objective of this paper is to examines the mediating role of government policies in supporting digital adoption and fostering a conducive environment for digital entrepreneurship. This paper employed a quantitative method to examine the impact of digital economy engagement and digital adoption on the entrepreneurship performance of Small and Medium Enterprises (SMEs) in Malaysia, with a focus on the PG Mall platform. Through data analysis, this research assessed several hypotheses related to the relationship between digital engagement, adoption, and business performance. The findings revealed that the majority of the hypotheses were supported, confirming the positive influence of digital economy engagement and digital adoption on various aspects of entrepreneurship performance. Based on these findings, this paper also proposes a conceptual framework that highlights the elements of digital economy engagement and digital adoption that contribute to SME performance. This framework serves as a valuable guideline for government policymakers, practitioners, and scholars in shaping strategies to foster digital entrepreneurship. It underscores the importance of supportive government policies, such as financial incentives and training, in facilitating the digital transformation of SMEs. By providing a structured approach to understanding the role of digital tools in enhancing business outcomes, the framework offers a foundation for future research and policy development aimed at promoting digital entrepreneurship in an evolving economic landscape.
El espejo de Carroll: recorrido editorial, gráfico y social por las ediciones de Alicia
Authors: López Guix Juan Gabriel
Published: January 2025

El repaso histórico de las ediciones de Alicia en el país de las maravillas y A través del espejo de Lewis Carroll publicadas en España en las diferentes lenguas desde la primera aparición aliciana en 1914 ofrece un inesperado marcador de tendencias y dinámicas mucho más amplias, tanto editoriales como políticas y culturales. La mera cronología de las ediciones y las diferentes lenguas ofrece un reflejo de los acontecimientos históricos transcurridos a lo largo de más de un siglo y muestra también tendencias culturales y usos de la LIJ.
Feeding the future: text typology in agri-food translation
Authors: Morales-Jiménez Juan Pedro
Published: January 2025

Reseña de Feeding the future: text typology in agri-food translationRivas Carmona, María del Mar y Ruiz Romero, María de los Ángeles.Publicacions Universitat de València, Valencia, 2021, 252 pp.
Videojuegos para el desarrollo de la competencia traductora en el Espacio Europeo de Educación Superior
Authors: Melgar Iraqui Nora
Published: January 2025

Reseña de Videojuegos para el desarrollo de la competencia traductora en el Espacio Europeo de Educación Superior.José Ramón Calvo-Ferrer.Valencia, Tirant lo Blanch, 2023, 170 pp.
UNAPREĐENJE PROIZVODNOG SISTEMA „UKS SHOP“ PRIMENOM LEAN ALATA
Authors: Roksandić Ana
Published: January 2025

Ovaj rad istražuje teorijske osnove i praktičnu primenu LEAN metodologije u unapređenju efikasnosti proizvodnog sistema. Praktična primena unapređenja sprovedena je u proizvodnom sistemu „UKS Shop“, specijalizovanom za izradu proizvoda od drveta. Kroz analizu LEAN principa, alata i metoda, kao i kroz konkretne primere njihove primene u praksi, rad pruža uvid u koristi primene LEAN koncepta u proizvodnom sistemu, sa ciljem eliminacije gubitaka, poboljšanja kvaliteta proizvodnje i smanjenja troškova.
ANALIZA UTICAJA DOGAĐAJA NA LOKALNU ZAJEDNICU
Authors: Stojković Anja
Published: January 2025

U radu je detaljno analiziran uticaj lokalno organizovanih događaja na zajednicu. Cilj je identifikovati strategije i pristupe koji mogu poboljšati pozitivne efekte događaja, minimizirati potencijalne negativne uticaje i doprineti održivom razvoju zajednice. Predmet istraživanja ovog rada jeste praktična primena EMBOK modela u organizaciji lokalnih događaja s fokusom na unapređenje njihovog uticaja na lokalnu zajednicu.
POVEĆANJE MOTIVACIJE TIMOVA U IT PROJEKTIMA KROZ PRIMENU GEJMIFIKACIJE
Authors: Lazić Mario
Published: January 2025

Sve kompleksniji i međusobno povezani problemi savremenog sveta zahtevaju primenu i međusobno povezivanje niza znanja u zajedničku celinu. To iziskuje psihički napor koji niko ne bi uložio da nema motivacije. Zato je nedostatak motivacije opasan problem u timskom radu. Studija slučaja sprovedena je u kompaniji ,,ContinentalAG“ u Novom Sadu, gde je primećeno da je nivo zainteresovanosti timova programera znatno nizak, a da sastanak Retrospektive sprinta po tom pitanju trpi najviše. Kao potencijalno rešenje ovog problema vidi se pristup zvan Gejmifikacija.
UNAPREĐENJE PROCESA SKLADIŠTENJA U PREDUZEĆU TEHNOMEDIA CENTAR DOO ZAJEČAR
Authors: Stanojević Katarina
Published: January 2025

U teorijskom delu rada analiziran je pojam logistike i skladištenja, kao i metode „5Zašto“ i Ishikawa. U praktičnom delu rada analizirano je trenutno stanje skladišta kompanije Tehnomedia centar. Primenom pomenutih metoda dolazi se do ključnih problema. U zaključnom delu rada su prikazana dva predloga unapređenja.
ISTRAŽIVANJE INTERNIH KOMUNIKACIJA U OBRAZOVNIM USTANOVAMA
Authors: Vesić Dragana
Published: January 2025

U okviru rada izvršeno je istraživanje internih komunikacija u osnovnoj školi. Kroz teorijski osvrt izdvojeni su sistemi komuniciranja koji prate poslovanje u svakoj fazi. Dato je značenje pojma komunikacija, definisani su različiti uticaji na procese komuniciranja, kao i problemi koji mogu nastati u poslovnom komuniciranju. Istaživački deo rada bazira se na kreiranom upitniku i sprovedenom istraživanju o stavovima zaposlenih, dok je na osnovu rezultata istraživanja predložen niz mera unapređenja po uzoru na primere dobre prakse.
УНАПРЕЂЕЊЕ ЛОГИСТИЧКИХ ПРОЦЕСА У ПРЕДУЗЕЋУ ,,АУТОМАТЕРИЈАЛ ДОО ШАБАЦ“
Authors: Перић Јована
Published: January 2025

Предмет овог рада је унапређење логистичких процеса у предузећу „Аутоматеријал доо Шабац“. У теоријском делу је представљен значај логистике и логистичких процеса: транспорта, набавке и складиштења. У практичном делу рада је представљено предузеће које је предмет рада и приказано је како у овом предузећу функционише транспорт, набавка и складиштење. Затим је урађен снимак стања предузећа уз помоћ две анализе: SWOT и Ishikawa дијаграм, где су кроз резултате анализа уочени недостаци, а потом су дати предлози унапређења.
RAZVOJ I TESTIRANJE MODULA KASKADE U SISTEMU VAZDUHA POD PRITISKOM
Authors: Buač Todor
Published: January 2025

U ovom radu je prikazan razvoj modula kaskade kao i primena u sistemima vazduha pod pritiskom. Uređaj služi za sistemsko rešavanje pojave neželjenog signala u sistemu vazduha pod pritiskom. Za potrebe testiranja funkcionalnosti modula kaskade meren je parametar protoka vazduha pod pritiskom i poređen je sa komercijalno dostupnom metodom taktnih lanaca za isti problem. Rezultati su detaljno prikazani i analizirani.
INTEGRACIJA PRINCIPA ODRŽIVOG RAZVOJA U UPRAVLJANJE SAOBRAĆAJNIM INFRASTRUKTURNIM PROJEKTIMA
Authors: Savić Bojana
Published: January 2025

Rad se bavi integracijom principa održivog razvoja u upravljanje saobraćajnim infrastrukturnim projektima. Poseban akcenat je stavljen na analizu visokobrzinskih železnica Eurostar i Thalys, sistema masovnog brzog prevoza u Singapuru i Big Dig megaprojeka u Bostonu kroz pristup procene životnog ciklusa (LCA). Primena PESTEL analize omogućava identifikaciju ključnih faktora koji utiču na uspeh ili neuspeh integracije održivosti u saobraćajne infrastrukturne projekte.
IMPLEMENTACIJA AGILNIH METODOLOGIJA UPRAVLJANJA SOFTVERSKIM PROJEKTIMA - UPOREDNA ANALIZA PRIMENE U TEORIJI I PRAKSI
Authors: Petrov Dina
Published: January 2025

Nastanak agilnih metodologija i radnih okvira poput Skrama korenito su promenili pristup upravljanju softverskim projektima. Mada oni pred¬stav¬ljaju moćne alate stvorene s namerom prevazilaženja iza¬zova tradicionalnih pristupa, postavlja se pitanje o njihovoj realističnoj praktičnoj primeni u industriji, i da li su IT kompanije dosledne pravilima i principima ovih metodologija.
DEMO OKRUŽENJE ZA ANALIZU NAJČEŠĆIH SLABOSTI APLIKATIVNIH PROGRAMABILNIH INTERFEJSA (API)
Authors: Simeunović Milica
Published: January 2025

Neprofitna organizacija OWASP redovno objavljuje listu od deset najčešćih slabosti aplikativnih programabilnih interfejsa (API). Cilj ovog rada je razvoj demo okruženja za praktično prikazivanje tih slabosti, odnosno prikaz optimalnih mera bezbednosti za otklanjanje istih. Demo okruženje se sastoji od slabe i zaštićene verzije API-ja koji je razvijen korišćenjem okvira NodeJS. U ovom radu su prikazane prvih pet slabosti i opisane optimalne mere bezbednosti za njihovo rešavanje.
ANALIZA PREDUZETNIČKIH KARAKTERISTIKA MLADIH ZA RAD U IT KOMPANIJAMA
Authors: Komanović Kosta
Published: January 2025

Cilj ovog istraživanje bio je da se istraže i prikažu koje su to preduzetničke karakteristike potrebne mladima da pokrenu sopstveni preduzetnički poduhvat ili da učestvuju u već postojećim. Ovaj pristup omogućava identifikovanje problema i pružanje konkretnih smernica za stvaranje produktivnijeg i inovativnijeg preduzetništva mladih. Istraživanje je sprovedeno kod studentske populacije putem standardizovanih upitnika. Na kraju predstavljeni su rezultati istraživanja i zaključna razmatranja.. Istraživanjem je obuhvaćeno 192 studenta.. Dobijeni rezultati pokazali su da veliki broj studenata ima razvijene preduzetničke karakteristike ali postoje i studenti kod koji se one trebaju razvijati i unapređivati. Time se postiže kreiranje uspešnih mladih preduzetnika.
ANTIOXIDANT AND HEPATOPROTECTIVE ACTIVITY OF ETHANOLIC EXTRACTS OF BARK OF ZANTHOXYLUM ARMATUM DC IN PARACETAMOL-INDUCED HEPATOTOXICITY
Authors: Ranawat Lalit Singh , Patel Jagruti
Published: January 2025

The scientific evaluation of medicinal plants used in the preparation of folk remedies has provided modern medicine with effective pharmaceuticals for the treatment of diseases. The ethanolic extract of Zanthoxylum armatum DC bark was investigated for its hepatoprotective and antioxidant effects on Paracetamol (500 mg/kg) induced acute liver damage in Wistar albino rats. Hepatoprotection activity was measured by using biochemical parameters such as serum glutamate oxalate transaminase and se-rum Glutamate Pyruvate Transaminase (SGOT and SGPT), alkaline phosphatase (ALP), bilirubin and total protein. The ethanolic extract of Zanthoxylum armatum DC(EZA) at the doses of (100 mg/kg ,200 mg/Kg and 400 mg/Kg) produced significant hepatoprotective effect by decreasing the activity of serum enzymes, bilirubin and lipid peroxidation while it significantly increased the levels of glutathione (GSH), catalyse (CAT) and super oxide dismutase (SOD) in a dose dependant manner. The effects of EZA were comparable to that of standard drug silymarin. These results suggest that EZA may have potential therapeutic value in the treatment of some liver disorders, probably by its antioxidative effect on hepatocytes.
TOXICOLOGICAL EVALUATION OF ROOT METHANOLIC EXTRACT OF STROBILANTHES HEYNEANUS NEES USING ALLIUM TEST
Authors: K. Renjana P. , Thoppil John E.
Published: January 2025

Cytotoxic and genotoxic effects of methanolic extract of the roots of Strobilanthes heyneanus Nees have been studied on the root meristem cells of Allium cepa. Roots of A. cepa were exposed to different concentrations (0.01%, 0.05%, 0.1% and 0.5%) of the extract for ½, 1, 2 and 3 h. Mitotic index and chromosomal aberrations in the treated cells were analysed. Distilled water has been used as control. Mitotic index val¬ues were decreased with increasing concentrations and longer treatment durations compared to the control (p < 0.05) in dose and time dependent manner. Additionally, different abnormal mitotic figures were observed in all treatments. Among these abnormalities were nuclear and chromosome lesions, anaphase bridges, C-mitosis, pulverization, stathmo-anaphases, diagonal orientation, chromosome fragments etc. The total percentage of aberrations generally increased with increasing concentrations of the extract and longer durations of exposure. The observations of the present study are a clear indication of clastogenic and non-clastogenic property of the extract, which is evident from the direct actions on the chromosomes and manifestation of spindle abnormalities.
PRONIOSOMES: A SUPERIOR DRUG DELIVERY SYSTEM
Authors: Venkatesh D. Nagasamy , Priyanka V. Swetha , Tulasi K. , Kalyani K. , Ali Sheik Abid , Jilakara Harikrishna
Published: January 2025

Proniosomes are solid colloidal particles which may be hydrated immediately before use to yield aqueous niosomes dispersions similar to those produced by more cumbersome conventional methods. The proniosomes minimize the problems associated with niosomes in terms of its physical stability such as aggregation, fusion and leaking. They also offer an additional convenience in transportation, distribution, storage, and dosing. The proniosomes derived niosomes are better than conventional niosomes in terms of their morphology, particle size, particle size distribution, and drug release. A slurry method was commonly used to produce proniosomes using maltodextrin as carrier. The time required to produce proniosomes by this simple method is independent of the ratio of surfactant solution to carrier material and appears to be a scalable process. The encapsulation efficiency of proniosomes is depends upon the amount of maltodextrin used in the process. The present review describes the method of preparation, characterization, applications of proniosomes as a potential drug delivery system.
HUTCHINSON-GILFORD PROGERIA SYNDROME: A PREMATURELY AGING DISORDER
Authors: Goyal Ahsas , Agrawal Neetu , Semwal Bhupesh C. , Murti Yogesh
Published: January 2025

Hutchinson-Gilford Progeria Syndrome (HGPS) is an extremely rare genetic disorder characterized by premature aging, involving aberrant splicing of the LMNA gene, resulting in the production of a disease-causing mutant lamin A protein called progerin. Clinical manifestations are evident by the first or second year of life and include the physical characteristics usually associated with the elderly. Because neither parent carries or expresses the mutation, each case is believed to represent a sporadic, new mutation that happens most notably in a single sperm or egg immediately prior to conception. Clinical trials investigating farnesyltransferase inhibitors (FTIs), statins, and bisphosphonates as HGPS treatments are currently underway. FTIs prevent farnesylation and localization of progerin to the cell membrane but do not repair the function of the abnormal progerin protein within the cytoplasm that may result in abnormalities in cell function and DNA repair that, therefore, would not be treated with these drugs. Thus some other novel treatment strategies are required for the more effective treatment. This review summarizes the clinical characteristics of this disease, the underlying mutation in the lamin A (LMNA) gene that results in this phenotype and the recent advances in treatment strategies.
IN VITRO ANTI DERMATOPHYTE ACTIVITIES OF CRUDE METHANOL AND AQUEOUS EXTRACTS OF LAWSONIA INERMIS
Authors: Ekwealor C. C. , Oyeka C. A.
Published: January 2025

The present study was carried out to investigate the in vitro anti dermatophyte activities of crude methanol and aqueous extracts of Lawsonia inermis leaves. The anti dermatophyte activities was tested against Microsporum audouinii, Microsporum ferrugineum, Trichophyton megninii, Trichophyton tonsurans and Trichophyton rubrum, recovered from rice farmers with fungal skin infections in Anambra State, Nigeria. From the result obtained, growth of dermatophytes was inhibited at the varied concentrations of crude methanol extract with the diameter zone of inhibition increasing with the increase in concentration. At the lowest concentration of 10 mg/disc, diameter zone of inhibition range of 8.0 mm-16.8 mm was recorded against the different dermatophytes. At 80 mg/disc, T. rubrum showed the highest diameter zone of inhibition (18.8 mm), followed by M. audouinii (18.0 mm) while T. megninii was the least inhibited (12.0 mm). Water extract of L. inermis also inhibited all the test dermatophyte. M. audouinii was the most susceptible with diameter inhibition zone of 14.5 mm. Minimum inhibitory concentration was recorded at 25 mg/ml for all dermatophytes while fungicidal action was recorded at concentrations of 50 mg/ml for M. audouinii and T. rubrum, 100 mg/ml for M. ferrugineum and 200 mg/ml for T. megninii and T. tonsurans. These results demonstrated that L. inermis has anti dermatophyte activities and could be a good source for the production of plant based antifungal drugs.
STABILITY INDICATING UV SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF DRONEDARONE HYDROCHLORIDE
Authors: Kardile Kshitija , Damle Mrinalini C.
Published: January 2025

The objective of this study was to develop stability UV method for estimation of Dronedarone Hydrochloride in tablet to compare % degradation of this drug determined by this UV method to HPTLC method reported by us earlier. Analysis of bulk as well as marketed tablet formulation by exposure to same degradative conditions was done and % degradation obtained by spectroscopy was determined. Method development and validation was done as per ICH guidelines. % degradation observed by both methods was comparable. The variation in the results of this drug estimated by HPTLC and spectrophotometric method was statistically insignificant. This suggests that the spectrophotometric method is suitable to determine stability profile. Hence a simple UV spectrophotometry can be used to monitor stability of Dronedarone Hydrochloride.
SIMPLE AND PRECISE UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT FOR ESTIMATION OF ALBENDAZOLE FOR DISSOLUTION STUDY
Authors: Agrawal Vipin Kumar , Chaturvedi Shashank , Gupta Amresh
Published: January 2025

Albendazole is a class II drug in biopharmaceutical classification system, so its dissolution study is very difficult because of its low solubility and difficulty during estimation of drug in bulk. The present study deals with UV spectrophotometric method development and validation for estimation of albendazole in bulk form. Albendazole is a benzimidazole derivative with an oral broad spectrum of activity against human and animal helminthes parasites. The drug obeyed the Beer’s law and showed good correlation. It showed absorption maxima at 229nm in 0.1 N HCL with 0.05% sodium lauryl sulphate (SLS). The linearity was observed between 4-20μg/ml. The method was applied for the analysis of the drug in the pure, tablet and suspension forms. The slope and intercept of the equation of the regression line are 0.009 and 0.017 respectively. Correlation coefficient was found to be 0.9996. The results of analysis were validated by recovery studies. The recovery was more than 97%. The method was found to be simple, reliable, rapid, precise, specific and reproducible and can be applied for routine analysis of albendazole in different dosage form and dissolution studies.
NEW RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF DESVENLAFAXINE AND CLONAZEPAM IN TABLETS
Authors: N Usha Rani , G Sahithi , K Divya
Published: January 2025

A simple, specific and precise high performance liquid chromatographic method was developed and validated for simultaneous determination of Desvenlafaxine and Clonazepam in tablets. The chromatographic separation was performed using Hypersil ODS C18 Column (4.6 × 250 mm, 5μm particle size). The mobile phase consisted of a combination of acetonitrile and 0.05 M ortho phosphate buffer (pH 4.0) in the ratio of 60:40 v/v at a flow rate of 1.2 ml/min with the detection wavelength at 225 nm. Both the drugs showed good linearity in the concentration range of 60-140μg/ml and 0.6-1.4μg/ml respectively. The correlation coefficients were obtained as 0.996 and 0.997 respectively for Desvenlafaxine and Clonazepam. The retention times for Desvenlafaxine and Clonazepam were found to be 2.687 and 3.817 min respectively. The developed analytical method was validated for linearity, precision, accuracy, ruggedness, robustness, specificity and system suitability according to ICH guidelines. The developed method can successfully be employed for routine quality control of Desvenlafaxine and Clonazepam in combined tablet dosage forms.
HPTLC METHOD DEVELOPMENT AND VALIDATION OF ZOLPIDEM TARTRATE IN BULK AND MARKETED FORMULATION
Authors: Shirode Abhay R. , Jadhav Bharti G. , Kadam Vilasrao J.
Published: January 2025

High performance thin layer chromatography (HPTLC) offers many advantages over HPLC. It reduces the cost of analysis as compare to HPLC. The mobile phase consumption per sample is extremely low in HPTLC, hence reducing the acquisition and disposal cost. Considering the cost and suitability of analysis for estimation of zolpidem tartrate in bulk and its marketed formulation, HPTLC method was developed and validated. The Camag HPTLC system, employed with software winCATS (ver.1.4.1.8) was used for the proposed analytical work. Planar chromatographic development was carried out with the help of Silica Gel 60 F254 precoated TLC plates. Sample application was facilitated by Linomat 5 applicator. After sample application plates were subjected for ascending development in twin trough chamber of 10×10 dimension, using 10 ml of solvent system. The optimised mobile phase was composed of ethyl acetate: methanol: acetonitrile (7:1.5:1.5 v/v/v). In post- development, the plates were air dried and then scanned densitometrically using a UV detector at 298 nm in absorbance mode. In HPTLC densitogram well defined peak was obtained for zolpidem tartrate with peak start position at 0.55 Rf , max position at 0.59 Rf and end position at 0.63 Rf. The optimal Rf value for zolpidem tartrate was found to be 0.58. Performance characteristics of HPTLC method for estimation of zolpidem tartrate in bulk and its marketed dosage form were statistically validated as per the recommendations of ICH guidelines of analytical method validation. The HPTLC method was found to be linear across the range 200- 800 ng/spot. The LOD and LOQ values were found to be 16.99 and 51.50 ng/spot respectively. The method was found to be accurate, precise, robust and economical for the analysis of zolpidem tartrate from bulk and its formulation.
KINETICS AND MECHANISM OF PERMANGANATE OXIDATION OF CIPROFLOXACIN IN AQUEOUS SULPHURIC ACID MEDIUM
Authors: Jain Ankita , Jain Shikha , Devra Vijay
Published: January 2025

The oxidation of ciprofloxacin (CIP) by permanganate ion in aqueous sulphuric acid medium at constant ionic strength (I = 0.05 mol dm-3) has been investigated spectrophotometrically at 525 nm. Order with respect to substrate, oxidant and acid concentrations were determined. Product characterization of reaction mixture indicates the formation of major product m/z 263 corresponding to dealkylation of the piperazine ring of ciprofloxacin. The piperazine moiety of ciprofloxacin is the predominant oxidative site to KMnO4. Product analysis indicates that oxidation of permanganate results in dealkylation at the piperazine moiety of ciprofloxacin, with the quinolone ring essentially intact. The reaction constants involved in different steps of the mechanism were calculated at different temperatures. The activation parameters with respect to the slow step of the mechanism were computed and thermodynamic quantities were also determined.
Bandera de Provincias y la filosofía
Authors: Aparicio Héctor
Published: January 2025

El siguiente texto explora la relación entre la filosofía y Bandera de Provincias al considerar algunos ensayos y traducciones publicados en la revista. En especial, se toman en cuenta los trabajos de Samuel Ramos y Agustín Yáñez, los cuales serían antecedentes de instituciones y corrientes filosóficas. Para ello, se describen las características de la revista, así como las sucesivas ediciones de la misma y los enlaces con otras revistas de su época, después se analizan los estudios que la han investigado, para rematar con el examen de los textos filosóficos de la publicación periódica. Por último, se dilucida brevemente las razones por las que se ignoró el nexo entre el ámbito filosófico y la revista en cuestión.
Bandera de Provincias and the Philosophy
Abstract
The following paper explores the relationship between the philosophy and Bandera de Provincias by considering some essays and translations published in this journal. In particular, it takes into account the works of Samuel Ramos and Agustín Yáñez, which would be antecedents of institutions and philosophical currents. For this purpose are described the characteristics of the journal, as well as the successive editions it has had and the links with other magazines; then the studies that have investigated it are analyzed to finish with the examination of the philosophical texts published in Bandera de Provincias. Finally, the reasons why the nexus between the philosophical field and the journal were ignored are briefly elucidated.
Recibido: 23 de junio de 2024Dictaminado:  30 de septiembre de 2024Aceptado: 26 de noviembre de 2024
Martha Elena Munguía Zatarain y Daniel Avechuco Cabrera (Coords.). (2024). Representaciones artísticas del indígena en América Latina
Authors: Parissi Joaquín
Published: January 2025

Martha Elena Munguía Zatarain y Daniel Avechuco Cabrera (Coords.). (2024). Representaciones artísticas del indígena en América Latina. 222 pp. ISBN: 978-607-8969-32-6. Xalapa: Universidad Veracruzana/Universidad de Sonora.
 
La justa comprensión de los pueblos originarios siempre ha constituido un problema para el arte nacional. Ya sea por el oscuro barniz de estereotipos que la recubre o por la lente deformante del pensamiento occidental, la figura del indígena ha padecido de idealizaciones almibaradas o barbarizantes. ¿Cómo explorar, con ojos nuevos, las representaciones del indio en la literatura popular del siglo XIX y las obras canónicas del XX?, ¿cómo aproximarnos a la literatura escrita en lenguas originarias?, ¿qué tanto se ha idealizado al indígena?, ¿cuánto se le ha menospreciado a partir de la dicotomía de civilización y barbarie?, ¿en qué medida la visión occidental del mundo ha alterado nuestras relaciones con estas culturas? Todas estas preguntas –y algunas más– han inspirado los artículos reunidos en este libro, necesarísimo para la revisión y mejoramiento de los estudios literarios de esta índole.
The Politics of Reparations in Rastafari Livity and Reggae
Authors: Eugene Chevy
Published: January 2025

In this paper, I explore the role of the Caribbean creative imagination in advancing the Caribbean reparations movement. To support my hypothesis on the role of the arts in reparations, I examine the politics of reparations in reggae music by my exploration of the studio albums of the most influential reggae artist - Bob Marley. The four themes underlined are: emancipation, chant down Babylon (destruction of the neoliberal construction of the world), repatriation, and the promised land.
Locating Caribbean Studies in Canada, Today: Conversations with Tameka Samuel-Jones, PhD and Audra Diptee, PhD
Authors: Diptée Audra , Pinnock Tka , Samuels-Jones Tameka
Published: January 2025

What is the state of Caribbean Studies in Canada today? 
In the spring of 2023, Chevy Eugene—Caribbeanist scholar and activist and doctoral candidate in Social and Political Thought at York University—lamented The Crisis of Caribbean Studies in Canada. That conversation brought together emerging and established scholars and activists of the Caribbean in Canada to consider the contemporary question of Caribbean Studies. It served as an anchor for a series of conversations I had with scholars in the Canadian academy in the summer of 2023 on the state and future of Caribbean Studies.
Cover Art "They Say We Can't Breathe Under Water"
Authors: Wood Natalie
Published: January 2025

Cover Art "They Say We Can't Breathe Under Water"
Answering the Blue Devil Call: Performing a repertoire of Resistance, Disruption, and Inspiration
Authors: Wood Natalie
Published: January 2025

This paper explores performance, disruption, and the decolonial forces of the Caribbean Carnival and the Blue Devil masquerade. The Blue Devil performance can be linked to African cultural traditions (Dabiri, 2019) which emerged within the pre and post emancipation Trinidad Carnival and the Jab Jab or Molasses devil masquerade (Mas). Both Carnival and Devil Mas symbolize resistance, ritual and rebellion as practiced by enslaved Africans and their descendants (Hill, 1972; Liverpool, 2001; Bakhtin, 1968). In this paper I discuss the performance of the Blue Devil in resisting and disrupting historical and contemporary forces of oppression. I tie the 'erotic' energy of Blue Devil to decolonial and abolition practices of imagining, creating, and inspiring strategies to change the world.
UNA EXPERIENCIA EMANCIPATORIA EN LA FORMACIÓN DE PROFESORES EN LA PREFECTURA DE SÃO PAULO-BRASIL, ENTRE 2001 Y 2004
Authors: Pisaneschi Lucilene , Cardoso Vania
Published: January 2025

Este artículo presenta una experiencia de formación de profesores experimentada por una de las autoras, entre 2001 y 2004, durante la actuación de Paulo Freire como Secretario de Educación. En el presente relato, se busca establecer un diálogo entre el pensamiento de Adorno y de Freire, con el fin de comprender la importancia y los límites presentados por tal experiencia en la formación de maestros en servicio. En este sentido,  la experiencia busca demostrar cómo los caminos recorridos por la Red de Educación Municipal de São Paulo durante este período, dieron lugar a condiciones sustanciales para los formadores y profesores para crear itinerarios de formación con mayor autonomía, lo que permitió la formación, de un cierto grado, de autonomía en la toma de decisiones acerca de la reformulación de los planes de estudio y las relaciones establecidas tradicionalmente dentro de los contextos escolares, constituyendo posibilidades reales de superar la tendencia histórica de los modelos prescriptivos que ignoran la escuela y sus individuos en su concreción social.
LAS ENCRUCIJADAS DE LO COMÚN. SISTEMATIZACIÓN DE UNA EXPERIENCIA DE ALFABETIZACIÓN DE ADULTO Y ADULTO MAYOR DESARROLLADA EN LA POBLACION EL CASTILLO
Authors: Durán Pereira Andrés , Abarca Fariel , Hidalgo Rodolfo , Vallejo Eugenia , Vera María Paz
Published: January 2025

El presente artículo sistematiza algunos elementos de la experiencia de alfabetización de adultos y adultos mayores, desarrollada durante el año 2017, en la población El Castillo, comuna de La Pintana. En particular, el texto se detiene sobre seis aspectos relevantes: posiciones biográficas de los habitantes, ansiedades y temores de pobladores, conformación del grupo de trabajo, aprendizajes subterráneos, dificultades del proceso, y desafíos a considerar para futuras experiencias de praxis comunitaria.
EXPERIENCIAS ALFABETIZADORAS EN LA ACTUAL REGIÓN DEL MAULE (CHILE): LA VISITA DE PAULO FREIRE, RECUERDOS Y LEGADO
Authors: Molina Jara Jorge Alejandro , Albornoz Moreno Valeria Constanza , Bernales Núñez María José , Ortiz Mejías Claudia Antonia
Published: January 2025

El educador brasileño Paulo Freire estuvo trabajando y contribuyendo en Chile a la alfabetización campesina. Al respecto, se han desarrollado algunas investigaciones que analizan esa experiencia, empero, dichos trabajos no recogen las experiencias regionales y locales de Freire a lo largo del país. Al respecto, la presente investigación exploratoria, pretende enfrentar dicho vacío desde una mirada regional, buscando conocer cómo fue el trabajo de Freire en la actual región del Maule, explicando cómo arribó, con qué instituciones se vinculó y qué estrategias de alfabetización desarrolló. Para objetos de esta investigación, utilizamos fuentes orales, rescatando relatos y memorias de personas que compartieron y se capacitaron con Freire en la actual región del Maule, junto a prensa y bibliografía que nos permitirán comprender las características de la zona en estudio.
EL USO DEL ANÁLISIS INSTITUCIONAL COMO RECURSO PEDAGÓGICO EN LA FORMACIÓN DOCENTE UNIVERSITARIA
Authors: Orozco Martínez Susana , Hormazábal Fajardo Roxana , Quiles-Fernández Emma
Published: January 2025

Este artículo presenta un proceso de investigación desarrollado en una Casa de Acogida (CA) de niños en situación de riesgo social en una provincia de Argentina, que es utilizado como recurso pedagógico en la formación universitaria de los nuevos maestros y educadores en la Universidad de Barcelona.  intención de acercarlos a la indagación socioeducativa. El abordaje de lo institucional en el proceso de investigación que se les presenta se realizó desde la perspectiva teórica-metodológica del análisis institucional, pero, teniendo en cuenta la complejidad que encierra toda institución, el proceso fue interactivo, adaptable y creciente con las aportaciones de distintos autores que permitieron entrelazar una red de significados que contribuyeron a la comprensión de lo que el proceso investigativo iba originando, moviendo y desencadenando tanto en quienes investigaban como con los participantes de la investigación. El proyecto de investigación se desarrolló durante seis meses por un equipo de investigadoras, y su desarrollo y resultados contribuyeron positivamente en los saberes de los estudiantes quienes se aproximaron al ámbito educativo con el desarrollo del pensamiento crítico, reconociendo la alteridad que los rodea e intervenir en consecuencia. Aquí presentamos, principalmente, la perspectiva y metodología del análisis institucional en investigación y cómo ha sido llevada a la formación como recurso pedagógico.
La ética como fundamento del hombre-sujeto en el pensamiento pedagógico de Paulo Freire
Authors: Méndez Rendón Juan Camilo
Published: January 2025

La pregunta por el sujeto es una de las cuestiones fundamentales de la losofía a lo largo de la historia del mundo occidental. Esta noción, de naturaleza ontológica, es, sin embargo, situada. Un rastreo diacrónico sobre la forma como se ha comprendido el sujeto en diferentes momentos de la historia demuestra que este es tanto consecuencia como condición del sistema-mundo en el que se halla. Basados en este precepto, el presente artículo busca situar el lugar de la ética en el pensamiento de Paulo Freire a partir de su noción de hombre-sujeto latinoamericano. Para ello, emplearemos un método de revisión documental de una selección de obras del pedagogo brasileño en articulación con las posturas éticas de algunos pensadores de la losofía contemporánea (Lévinas, Moore, Hinkelammert) que ponen en discusión el lugar de lo ético en la noción de hombre-sujeto en el pensamiento freiriano. De este análisis se deriva que el horizonte ético en la pedagogía de la liberación concuerda con las posturas de reconocimiento del otro como condición de formación del ser, puesto que la educación tiene una incidencia directa en este proceso, ya que educar es de suyo un ocurrir ético.
La articulación de la investigación narrativa, la intervención y la ética en la formación de docentes y profesionales de la educación
Authors: Poujol Galván Guadalupe
Published: January 2025

La crisis civilizatoria actual que amenaza la vida, la comunidad y la dignidad de las personas ha generado respuestas desde la pedagogía crítica y, en particular, en el campo de la formación docente. El propósito de este artículo es problematizar dicha formación, abordándola con una metodología que articula la investigación narrativa y la intervención educativa. Como resultado de este proceso, las profesoras narran cómo van transformando sus visiones sobre sí mismas, sus estudiantes, la educación, el mundo, y cómo toman posesión de su trabajo docente. Por un lado, el análisis del proceso formativo en el que se articulan la investigación y la intervención educativa con énfasis en la praxis-ética-política, la intersubjetividad-subjetividad-corporalidad, la creatividad-afectividad-reexión, la autonomía-responsabilidad social, revela la denuncia del despojo material y simbólico a los sujetos y las comunidades, lo que incluye el sentido de laeducación, del trabajo docente y su historicidad. Por el otro, en sus narraciones las docentes anuncian la esperanza, como lo ha planteado Freire, construyendo con sus estudiantes comunidades de vida, nuevas formas de subjetividad, socialidad y saberes para la solidaridad.
Historias de niños. Repensando conceptos de masculinidades a partir de la sistematización de una experiencia educativa en Brasil
Authors: Vasconcelos Valéria , Toledo Vanessa , Oliveira Danielle , Marques Gabriela , Moreira Laryssa , Soldera Tabata
Published: January 2025

Las normas de conducta históricamente construidas en Brasil apoyan la estructura patriarcal impuesta intensamente por medio de la colonización europea. Cuando la sociedad reproduce y valida solo un patrón de comportamiento como correcto, refuerza posturas sexistas y autoritarias. La experiencia aquí sistematizada siguió los aportes teóricos de Oscar Jara y tuvo como objetivo investigar las concepciones de algunos niños sobre conceptos de feminidad/masculinidad y problematizar diferentes cosmovisiones, para reforzar la creación de valores más equitativos. A través de los círculos de conversación, buscamos relevar estereotipos retratados en el cine y en la literatura infantil que naturalizan la jerarquía y la dominación machista. Los resultados muestran cómo el machismo está arraigado en el imaginario social y se maniestadesde temprana edad. Concluimos que es posible romper lógicas impuestas que refuerzan diferentes tipos de relaciones sociales marcadas por la desigualdad. La cultura se construye social e históricamente, así como las ideologías, por lo que es fundamental un cambio de pensamiento y una conciencia crítica por parte de los sujetos.