bluuebunny/crossref_metadata_2025 huggingface dataset:
Figures S1 - S9 from BMX-Mediated Regulation of Multiple Tyrosine Kinases Contributes to Castration Resistance in Prostate Cancer
Authors: Chen Sen , Cai Changmeng , Sowalsky Adam G. , Ye Huihui , Ma Fen , Yuan Xin , Simon Nicholas I. , Gray Nathanael S. , Balk Steven P.
Published: April 2023

Figure S1. Inducible BMX knockdown suppresses CWR22RV1 tumor growth in vitro and in vivo; Figure S2. Schematic picture of BMX signaling pathway; Figure S3. The effect of BMX SiRNA smart pool on CWR22RV1 cell response to serum stimulation; Figure S4. The specificity of BMX antibody; Figure S5. Affymetrix microarray expression of BMX in PCa patients; Figure S6. BMX mRNA expression is repressed by DHT; Figure S7. BMX knockdown in CWR22RV1 cells; Figure S8. AR binding site sequence in BMX loci; Figure S9. DHT effect on expression of AR and associated proteins.
Supplementary Materials and Methods from Tumor-Derived TGFβ Alters the Ability of Plasmacytoid Dendritic Cells to Respond to Innate Immune Signaling
Authors: Terra Mariana , Oberkampf Marine , Fayolle Catherine , Rosenbaum Pierre , Guillerey Camille , Dadaglio Gilles , Leclerc Claude
Published: April 2023

Media, buffers, TLR ligands and recombinant cytokines and chemokines, Tumor cell lines, Flow cytometry analysis,Transcriptomic analysis of pDCs
Figure S7 from Zika Virus Selectively Kills Aggressive Human Embryonal CNS Tumor Cells In Vitro and In Vivo
Authors: Kaid Carolini , Goulart Ernesto , Caires-Júnior Luiz C. , Araujo Bruno H.S. , Soares-Schanoski Alessandra , Bueno Heloisa M.S. , Telles-Silva Kayque A. , Astray Renato M. , Assoni Amanda F. , Júnior Antônio F.R. , Ventini Daniella C. , Puglia Ana L.P. , Gomes Roselane P. , Zatz Mayana , Okamoto Oswaldo K.
Published: April 2023

Dose-dependent effects of Wnt signaling modulators in different CNS tumor cell lines.
Figure S6 from Zika Virus Selectively Kills Aggressive Human Embryonal CNS Tumor Cells In Vitro and In Vivo
Authors: Kaid Carolini , Goulart Ernesto , Caires-Júnior Luiz C. , Araujo Bruno H.S. , Soares-Schanoski Alessandra , Bueno Heloisa M.S. , Telles-Silva Kayque A. , Astray Renato M. , Assoni Amanda F. , Júnior Antônio F.R. , Ventini Daniella C. , Puglia Ana L.P. , Gomes Roselane P. , Zatz Mayana , Okamoto Oswaldo K.
Published: April 2023

Molecular characterization and stem cell properties of USP7-ATRT cell line.
Figure S1 from Astrocyte Elevated Gene-1 Regulates Macrophage Activation in Hepatocellular Carcinogenesis
Authors: Robertson Chadia L. , Mendoza Rachel G. , Jariwala Nidhi , Dozmorov Mikhail , Mukhopadhyay Nitai D. , Subler Mark A. , Windle Jolene J. , Lai Zhao , Fisher Paul B. , Ghosh Shobha , Sarkar Devanand
Published: April 2023

This figure shows authenticity of LSEC by stabilin-2 immunostaining.
Aleksic_Supplementary data from Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage
Authors: Aleksic Tamara , Gray Nicki , Wu Xiaoning , Rieunier Guillaume , Osher Eliot , Mills Jack , Verrill Clare , Bryant Richard J. , Han Cheng , Hutchinson Kathryn , Lambert Adam G. , Kumar Rajeev , Hamdy Freddie C. , Weyer-Czernilofsky Ulrike , Sanderson Michael P. , Bogenrieder Thomas , Taylor Stephen , Macaulay Valentine M.
Published: April 2023

Supplementary file containing: Supplementary methods Table S1: Primers, probes and siRNAs used in this study. Table S2: Demographics of men treated by radical prostatectomy for prostate cancer. Table S3: IGF-1R scores and clinical parameters in men undergoing radical prostatectomy for localized prostate cancer. Table S4: ChIP-seq: mapped reads. Figure S1: Characterization of IGF-1R expression and subcellular localization in prostate cancer. Figure S2: IGF-1R ChIP-seq in human cancer cells containing nuclear IGF-1R. Figure S3: ChIP-seq identifies IGF-1R binding peaks in promoters of JUN and FAM21 but not CCDN1 or IGF1R. Figure S4: Investigating functional consequences of coincidence of IGF-1R and RNAPol2 recruitment to JUN and FAM21A promoters. Figure S5: Depletion of JUN or FAM21A delays migration towards IGF-1 but has no effect on short-term proliferation. Figure S6: JUN expression does not correlate with total IGF-1R in prostate cancer.
Supplementary Methods from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma
Authors: Braekeveldt Noémie , von Stedingk Kristoffer , Fransson Susanne , Martinez-Monleon Angela , Lindgren David , Axelson Håkan , Levander Fredrik , Willforss Jakob , Hansson Karin , Øra Ingrid , Backman Torbjörn , Börjesson Anna , Beckman Siv , Esfandyari Javanshir , Berbegall Ana P. , Noguera Rosa , Karlsson Jenny , Koster Jan , Martinsson Tommy , Gisselsson David , Påhlman Sven , Bexell Daniel
Published: April 2023

Supplementary methods and legends to supplementary figures and tables
Supplementary Figure 4 from CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells
Authors: Jung In-Young , Kim Yoon-Young , Yu Ho-Sung , Lee Myoungsoo , Kim Seokjoong , Lee Jungmin
Published: April 2023

DGK KO does not induce perturbation in CAR expression and non-specific anti-tumor activity.
Figure S2 from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma
Authors: Braekeveldt Noémie , von Stedingk Kristoffer , Fransson Susanne , Martinez-Monleon Angela , Lindgren David , Axelson Håkan , Levander Fredrik , Willforss Jakob , Hansson Karin , Øra Ingrid , Backman Torbjörn , Börjesson Anna , Beckman Siv , Esfandyari Javanshir , Berbegall Ana P. , Noguera Rosa , Karlsson Jenny , Koster Jan , Martinsson Tommy , Gisselsson David , Påhlman Sven , Bexell Daniel
Published: April 2023

Supplementary Figure S2. Related to Figure 4. Intratumor heterogeneity is less prominent than intertumor heterogeneity.
Supplementary Figure 1 from CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells
Authors: Jung In-Young , Kim Yoon-Young , Yu Ho-Sung , Lee Myoungsoo , Kim Seokjoong , Lee Jungmin
Published: April 2023

Sequences and efficiencies of guide RNAs used in this study.
Table S2 from LIFEx: A Freeware for Radiomic Feature Calculation in Multimodality Imaging to Accelerate Advances in the Characterization of Tumor Heterogeneity
Authors: Nioche Christophe , Orlhac Fanny , Boughdad Sarah , Reuzé Sylvain , Goya-Outi Jessica , Robert Charlotte , Pellot-Barakat Claire , Soussan Michael , Frouin Frédérique , Buvat Irène
Published: April 2023

Examples of published articles that used LIFEx to produce results with biological or clinical impact.
Table S1 from LIFEx: A Freeware for Radiomic Feature Calculation in Multimodality Imaging to Accelerate Advances in the Characterization of Tumor Heterogeneity
Authors: Nioche Christophe , Orlhac Fanny , Boughdad Sarah , Reuzé Sylvain , Goya-Outi Jessica , Robert Charlotte , Pellot-Barakat Claire , Soussan Michael , Frouin Frédérique , Buvat Irène
Published: April 2023

Well-known software programs that enable the calculation of radiomic features and associated characteristics.
Figure S1 from LIFEx: A Freeware for Radiomic Feature Calculation in Multimodality Imaging to Accelerate Advances in the Characterization of Tumor Heterogeneity
Authors: Nioche Christophe , Orlhac Fanny , Boughdad Sarah , Reuzé Sylvain , Goya-Outi Jessica , Robert Charlotte , Pellot-Barakat Claire , Soussan Michael , Frouin Frédérique , Buvat Irène
Published: April 2023

Distribution of SUVpeak, Entropy, HGZE, and SRE in healthy tissues and in tumors as a function of the voxel size: in blue for 4x4x4 mm3, in green for 2x2x2 mm3 and in pink for 1x1x1 mm3.
Supplementary Fig. S5 from CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis
Authors: Penfold Lucy , Woods Angela , Muckett Phillip , Nikitin Alexander Yu. , Kent Tera R. , Zhang Shuai , Graham Rebecca , Pollard Alice , Carling David
Published: April 2023

Migration in prostate cancer cell lines treated with 991.
Supplementary Fig. S3 from CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis
Authors: Penfold Lucy , Woods Angela , Muckett Phillip , Nikitin Alexander Yu. , Kent Tera R. , Zhang Shuai , Graham Rebecca , Pollard Alice , Carling David
Published: April 2023

Characterisation of Prkab1 KO mouse phenotype.
Table S13, Table S14 from Transcriptomic Differences between Primary Colorectal Adenocarcinomas and Distant Metastases Reveal Metastatic Colorectal Cancer Subtypes
Authors: Kamal Yasmin , Schmit Stephanie L. , Hoehn Hannah J. , Amos Christopher I. , Frost H. Robert
Published: April 2023

Table S13. Adjusted and unadjusted logistic regression modeling results for CMS association with M1 and M2 clusters of metastases for the MCC dataset. Table S14. Comparison of primary CRC tumors in the MCC dataset, which either go on to develop liver metastases or lung metastases for their initial distal metastasis. The down direction indicates enrichment in primary tumors which go on to develop lung metastases, whereas the up direction indicates enrichment in primary tumors which go on to develop liver metastases
Figure S2 from Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes
Authors: Bu Wen , Liu Zhenyu , Jiang Weiyu , Nagi Chandandeep , Huang Shixia , Edwards Dean P. , Jo Eunji , Mo Qianxing , Creighton Chad J. , Hilsenbeck Susan G. , Leavitt Andrew D. , Lewis Michael T. , Wong Stephen T. C. , Li Yi
Published: April 2023

Mutated Ras is sufficient to transform precancerous cells in the MMTV-Wnt1 mammary glands into cancer
Supplementary Data from Cholesterol Induces Epithelial-to-Mesenchymal Transition of Prostate Cancer Cells by Suppressing Degradation of EGFR through APMAP
Authors: Jiang Siyuan , Wang Xuetong , Song Dalong , Liu XiaoJun , Gu Yinmin , Xu Zhiyuan , Wang Xiaodong , Zhang Xiaolu , Ye Qinong , Tong Zhou , Yan BingXue , Yu Jie , Chen Yunzhao , Sun Minxuan , Wang Yang , Gao Shan
Published: April 2023

Supplementary Figures including Figure S1-S6. Title page includes the description of each figures .
Table S1-3 from ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis
Authors: Lu Yun-Xin , Ju Huai-Qiang , Liu Ze-Xian , Chen Dong-Liang , Wang Yun , Zhao Qi , Wu Qi-Nian , Zeng Zhao-lei , Qiu Hai-Bo , Hu Pei-Shan , Wang Zhi-Qiang , Zhang Dong-Sheng , Wang Feng , Xu Rui-Hua
Published: April 2023

Table S1. Primers sequence for qPCR Table S2. The correlation between clinicopathological parameters and ME1 expression Table S3. Univariate and multivariate analyses of various potential prognostic factors in GC patients
Supplementary figure legends from ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis
Authors: Lu Yun-Xin , Ju Huai-Qiang , Liu Ze-Xian , Chen Dong-Liang , Wang Yun , Zhao Qi , Wu Qi-Nian , Zeng Zhao-lei , Qiu Hai-Bo , Hu Pei-Shan , Wang Zhi-Qiang , Zhang Dong-Sheng , Wang Feng , Xu Rui-Hua
Published: April 2023

Figure legends for Figure S1-7.
Supplementary Data from Thrombin Signaling Promotes Pancreatic Adenocarcinoma through PAR-1–Dependent Immune Evasion
Authors: Yang Yi , Stang Amanda , Schweickert Patrick G. , Lanman Nadia A. , Paul Erin N. , Monia Brett P. , Revenko Alexey S. , Palumbo Joseph S. , Mullins Eric S. , Elzey Bennett D. , Janssen Edith M. , Konieczny Stephen F. , Flick Matthew J.
Published: April 2023

Table of differentially expressed genes from RNA-seq analysis of in vitro stimulation of KPC2 cells with and without thrombin.
Supplementary Data File 3 from Integrative Pharmacogenomics Analysis of Patient-Derived Xenografts
Authors: Mer Arvind S. , Ba-Alawi Wail , Smirnov Petr , Wang Yi X. , Brew Ben , Ortmann Janosch , Tsao Ming-Sound , Cescon David W. , Goldenberg Anna , Haibe-Kains Benjamin
Published: April 2023

Pathway stability in PDXs across passages for Hallmark pathway set.
Supplementary Data from PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness
Authors: Kaminski Lisa , Torrino Stéphanie , Dufies Maeva , Djabari Zied , Haider Romain , Roustan François-René , Jaune Emilie , Laurent Kathiane , Nottet Nicolas , Michiels Jean-François , Gesson Maeva , Rocchi Stéphane , Mazure Nathalie M. , Durand Matthieu , Tanti Jean-François , Ambrosetti Damien , Clavel Stephan , Ben-Sahra Issam , Bost Frédéric
Published: April 2023

Legends to supplementary data
Table S1 to S5 from CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms
Authors: Castillo Joseph , Wu Esther , Lowe Christopher , Srinivasan Shrividhya , McCord Ron , Wagle Marie-Claire , Jayakar Sangeeta , Edick Melissa Gonzalez , Eastham-Anderson Jeffrey , Liu Bonnie , Hutchinson Katherine E. , Jones Wendell , Stokes Matthew P. , Tarighat Somayeh S. , Holcomb Thomas , Glibicky Andrew , Romero F. Anthony , Magnuson Steven , Huang Shih-Min A. , Plaks Vicki , Giltnane Jennifer M. , Lackner Mark R. , Mounir Zineb
Published: April 2023

Supplementary table 1 shows the list of 2153 genes identified as the human Treg differentiation geneset. Supplementary table 2 shows the list of 2602 genes regulated by CBP/p300 bromodomain during Treg differentiation. Supplementary table 3 shows the list of 824 genes identified as Treg-specific CBP/p300 bromodomain-dependent geneset. Supplementary table 4 shows the list of 959 genes identified by H3K27Ac ChIPseq that are directly acetylated by CBP/p300 during Treg differentiation. Supplementary table 5 shows the list of 57 genes in the Treg-specific gene signature identified by combined analysis of H3K27Ac ChIPseq and RNAseq dataset analyses.
Figure S6 from CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms
Authors: Castillo Joseph , Wu Esther , Lowe Christopher , Srinivasan Shrividhya , McCord Ron , Wagle Marie-Claire , Jayakar Sangeeta , Edick Melissa Gonzalez , Eastham-Anderson Jeffrey , Liu Bonnie , Hutchinson Katherine E. , Jones Wendell , Stokes Matthew P. , Tarighat Somayeh S. , Holcomb Thomas , Glibicky Andrew , Romero F. Anthony , Magnuson Steven , Huang Shih-Min A. , Plaks Vicki , Giltnane Jennifer M. , Lackner Mark R. , Mounir Zineb
Published: April 2023

Supplementary figure 6 shows additional assessments of B cells in FL patient tissue samples and their activation status and supportive in vitro B cells findings.
Figure S3 from PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness
Authors: Kaminski Lisa , Torrino Stéphanie , Dufies Maeva , Djabari Zied , Haider Romain , Roustan François-René , Jaune Emilie , Laurent Kathiane , Nottet Nicolas , Michiels Jean-François , Gesson Maeva , Rocchi Stéphane , Mazure Nathalie M. , Durand Matthieu , Tanti Jean-François , Ambrosetti Damien , Clavel Stephan , Ben-Sahra Issam , Bost Frédéric
Published: April 2023

The downregulation of ODC1 inhibits PCa aggressiveness in ShPGC-1a cells
Figure S3 from CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms
Authors: Castillo Joseph , Wu Esther , Lowe Christopher , Srinivasan Shrividhya , McCord Ron , Wagle Marie-Claire , Jayakar Sangeeta , Edick Melissa Gonzalez , Eastham-Anderson Jeffrey , Liu Bonnie , Hutchinson Katherine E. , Jones Wendell , Stokes Matthew P. , Tarighat Somayeh S. , Holcomb Thomas , Glibicky Andrew , Romero F. Anthony , Magnuson Steven , Huang Shih-Min A. , Plaks Vicki , Giltnane Jennifer M. , Lackner Mark R. , Mounir Zineb
Published: April 2023

Supplementary figure 3 shows H3K27 acetylation ChIPseq QC analyses.
Figure S5 from Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer
Authors: Jain Aditi , Agostini Lebaron C. , McCarthy Grace A. , Chand Saswati N. , Ramirez AnnJosette , Nevler Avinoam , Cozzitorto Joseph , Schultz Christopher W. , Lowder Cinthya Yabar , Smith Kate M. , Waddell Ian D. , Raitses-Gurevich Maria , Stossel Chani , Gorman Yulia Glick , Atias Dikla , Yeo Charles J. , Winter Jordan M. , Olive Kenneth P. , Golan Talia , Pishvaian Michael J. , Ogilvie Donald , James Dominic I. , Jordan Allan M. , Brody Jonathan R.
Published: April 2023

Supplementary Figure S5 describes PARG ELISA.
Figure S4 from Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer
Authors: Jain Aditi , Agostini Lebaron C. , McCarthy Grace A. , Chand Saswati N. , Ramirez AnnJosette , Nevler Avinoam , Cozzitorto Joseph , Schultz Christopher W. , Lowder Cinthya Yabar , Smith Kate M. , Waddell Ian D. , Raitses-Gurevich Maria , Stossel Chani , Gorman Yulia Glick , Atias Dikla , Yeo Charles J. , Winter Jordan M. , Olive Kenneth P. , Golan Talia , Pishvaian Michael J. , Ogilvie Donald , James Dominic I. , Jordan Allan M. , Brody Jonathan R.
Published: April 2023

Supplementary Fig S4 describes synergy plots in Hs 766T cells.
Supplementary Figure 6 from Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Qin Haiyan , Ren Mingqiang , Savage Natasha M. , Chang Chang-Sheng , Cowell John K
Published: April 2023

Knockdown of RhoA in BaF3 cells using two different shRNA constructs shows only a proportional knockdown for shRhoA1 compared with an almost complete knockdown by shRhoA2
Figure S2 from Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer
Authors: Jain Aditi , Agostini Lebaron C. , McCarthy Grace A. , Chand Saswati N. , Ramirez AnnJosette , Nevler Avinoam , Cozzitorto Joseph , Schultz Christopher W. , Lowder Cinthya Yabar , Smith Kate M. , Waddell Ian D. , Raitses-Gurevich Maria , Stossel Chani , Gorman Yulia Glick , Atias Dikla , Yeo Charles J. , Winter Jordan M. , Olive Kenneth P. , Golan Talia , Pishvaian Michael J. , Ogilvie Donald , James Dominic I. , Jordan Allan M. , Brody Jonathan R.
Published: April 2023

Supplementary Fig S2 describes protein expression of PARG across PDAC cell models and drug sensitivity of PDAC, KPC, DLD and RKO cells to olaparib and/or PDDX-001.
Supplementary Figure 5 from Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Qin Haiyan , Ren Mingqiang , Savage Natasha M. , Chang Chang-Sheng , Cowell John K
Published: April 2023

BaF3 cells expressing either the full length, BCR-FGFR1 chimeric kinase or the deletion GEF were treated with the GSK690693 AKT inhibitor.
Supplementary Figure 4 from Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Qin Haiyan , Ren Mingqiang , Savage Natasha M. , Chang Chang-Sheng , Cowell John K
Published: April 2023

Analysis of bone marrow cell immunophenotypes from three individual mice transplanted with cells expressing the GEF deletion construct compared with bone marrow cells expressing the empty vector (MIG) control
Supplementary Figure 3 from Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Qin Haiyan , Ren Mingqiang , Savage Natasha M. , Chang Chang-Sheng , Cowell John K
Published: April 2023

Representative flow cytometric analysis of GFP+ cells from the spleens of mice transplanted with cells transduced with either the empty vector (MIG), full length BCR-FGFR1 chimeric kinase or GEF deletion construct.
Supplementary Figure 2 from Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Qin Haiyan , Ren Mingqiang , Savage Natasha M. , Chang Chang-Sheng , Cowell John K
Published: April 2023

Representative images of the peripheral blood, liver and spleen from mice transplanted with bone marrow transduced with either the empty vector (MIG), the full length BCR-FGFR1 chimeric kinase or the BCR-FGFR1 construct with deletion of the BCR GEF domain.
Supplementary Figure 1 from Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Qin Haiyan , Ren Mingqiang , Savage Natasha M. , Chang Chang-Sheng , Cowell John K
Published: April 2023

Representative examples of flow cytometric analysis of successful engraftment after 2 weeks in four mice with bone marrow cells transduced with either the empty vector (MIG), full-length BCR-FGFR1 or the deletion GEF construct.
Table S5, Table S6, Table S7, Table S8 from Single-Cell Transcriptome Analyses Reveal Endothelial Cell Heterogeneity in Tumors and Changes following Antiangiogenic Treatment
Authors: Zhao Qi , Eichten Alexandra , Parveen Asma , Adler Christina , Huang Ying , Wang Wei , Ding Yueming , Adler Alexander , Nevins Thomas , Ni Min , Wei Yi , Thurston Gavin
Published: April 2023

Table S5, Differentailly expressed genes in tumor EC subpopulations between anti-angiogenic drug-treatment and control hFc-treatment. Table S6, Differentailly expressed genes in heart EC subpopulations between anti-angiogenic drug treatment and control hFc treatment. Table S7, Differentailly expressed genes between COLO205-derived tumor stromal fibroblast (hFc-treated) and normal heart fibroblasts (hFc-treated). Table S8, Differentailly expressed genes in COLO205 tumor fibroblast (FB) and smooth muscle (SM) between anti-angiogenic drug and control hFc treatments.
Figure S7 from Remodeling the Tumor Microenvironment Sensitizes Breast Tumors to Anti-Programmed Death-Ligand 1 Immunotherapy
Authors: Clift Renee , Souratha Jennifer , Garrovillo Sheryl A. , Zimmerman Susan , Blouw Barbara
Published: April 2023

Pegvorhyaluronidase alfa effect on density of T-cells and NK cells and proportion of Gr1+ myeloid-derived suppressor cells in EMT-6 orthotopic breast tumors
Figure S5 from Remodeling the Tumor Microenvironment Sensitizes Breast Tumors to Anti-Programmed Death-Ligand 1 Immunotherapy
Authors: Clift Renee , Souratha Jennifer , Garrovillo Sheryl A. , Zimmerman Susan , Blouw Barbara
Published: April 2023

Anti-PD-L1 dose finding in EMT-6 tumors
Supplementary Video 1 from A Direct Podocalyxin–Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells
Authors: Wong Bin Sheng , Shea Daniel J. , Mistriotis Panagiotis , Tuntithavornwat Soontorn , Law Robert A. , Bieber Jake M. , Zheng Lei , Konstantopoulos Konstantinos
Published: April 2023

PODXL knockdown impairs 2D random migration of metastatic pancreatic cancer cells. Representative scramble control (left) and PODXL-KD (right) SW1990 cells migrating on collagen I-coated glass coverslips. Scale bar represents 50 µm. Related to Fig. 1B.
Table S6 from MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma
Authors: Hüllein Jennifer , Słabicki Mikołaj , Rosolowski Maciej , Jethwa Alexander , Habringer Stefan , Tomska Katarzyna , Kurilov Roma , Lu Junyan , Scheinost Sebastian , Wagener Rabea , Huang Zhiqin , Lukas Marina , Yavorska Olena , Helfrich Hanne , Scholtysik René , Bonneau Kyle , Tedesco Donato , Küppers Ralf , Klapper Wolfram , Pott Christiane , Stilgenbauer Stephan , Burkhardt Birgit , Löffler Markus , Trümper Lorenz H. , Hummel Michael , Brors Benedikt , Zapatka Marc , Siebert Reiner , Kreuz Markus , Keller Ulrich , Huber Wolfgang , Zenz Thorsten
Published: April 2023

Generanks for differential shRNA effects from GENE-E class comparison analysis for Achilles Project cell lines
Figure S5 from Glutamate Decarboxylase 65 Signals through the Androgen Receptor to Promote Castration Resistance in Prostate Cancer
Authors: Gao Yi , Chen Lu , Du ZunGuo , Gao WenChao , Wu ZhengMing , Liu XiuJuan , Huang Hai , Xu DanFeng , Li QingQuan
Published: April 2023

Figure S5 shows the effects of GAD65 knockdown on CRPC growth and progression
Table S2, Table S4, Table S6, Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Supplementary Methods from MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma
Authors: Hüllein Jennifer , Słabicki Mikołaj , Rosolowski Maciej , Jethwa Alexander , Habringer Stefan , Tomska Katarzyna , Kurilov Roma , Lu Junyan , Scheinost Sebastian , Wagener Rabea , Huang Zhiqin , Lukas Marina , Yavorska Olena , Helfrich Hanne , Scholtysik René , Bonneau Kyle , Tedesco Donato , Küppers Ralf , Klapper Wolfram , Pott Christiane , Stilgenbauer Stephan , Burkhardt Birgit , Löffler Markus , Trümper Lorenz H. , Hummel Michael , Brors Benedikt , Zapatka Marc , Siebert Reiner , Kreuz Markus , Keller Ulrich , Huber Wolfgang , Zenz Thorsten
Published: April 2023

Table S2. Genetic characterization of BL cell lines; Table S4. Genetic aberrations in aggressive B-NHL patients from the MMML consortium; Table S5. Annotation of TP53 mutation and MDM4 gain in cell lines from the Achilles project; Figure S1. RNAi screen identifies common and context-specific essential genes; Figure S2. Genes essential in the context of TP53 mutation; Figure S3. p53 reactivation causes cytotoxic effect; Figure S4. Molecular impact of MDM2 or MDM4 knock-down; Figure S5. Genetic profile in TP53wt and TP53mut aggressive B-NHL patients; Figure S6. Basal MDM4 mRNA in aggressive lymphomas stratified by TP53 mutation and 1q status.
Figure S4 from Glutamate Decarboxylase 65 Signals through the Androgen Receptor to Promote Castration Resistance in Prostate Cancer
Authors: Gao Yi , Chen Lu , Du ZunGuo , Gao WenChao , Wu ZhengMing , Liu XiuJuan , Huang Hai , Xu DanFeng , Li QingQuan
Published: April 2023

Figure S4 shows the binding of GABA, the product of GAD65, to AR in CRPC
Table S3 from Gaussian Mixture Models for Probabilistic Classification of Breast Cancer
Authors: Prabakaran Indira , Wu Zhengdong , Lee Changgun , Tong Brian , Steeman Samantha , Koo Gabriel , Zhang Paul J. , Guvakova Marina A.
Published: April 2023

Table S3. The summary of testing normality in cancer data sets.
Supplementary Tables from PIN1 Maintains Redox Balance via the c-Myc/NRF2 Axis to Counteract Kras-Induced Mitochondrial Respiratory Injury in Pancreatic Cancer Cells
Authors: Liang Chen , Shi Si , Liu Mingyang , Qin Yi , Meng Qingcai , Hua Jie , Ji Shunrong , Zhang Yuqing , Yang Jingxuan , Xu Jin , Ni Quanxing , Li Min , Yu Xianjun
Published: April 2023

Supplementary Table S1 showed the clinicopathological features and correlation of PIN1 expression in PDAC tissue samples. Supplementary Table S2 showed the human primers for quantitative PCR. Supplementary Table S3 showed the primers for Chromatin Immunoprecipitation (ChIP) assays. Supplementary Table S4. Showed the correlation of Kras status and PIN1 expression in PDAC patients. Supplementary Table S5 showed the correlation of ERK activation and PIN1 expression in PDAC patients. Supplementary Table S6 showed the Kras mutant status in the pancreatic cancer cell lines and HPDE examined in our study.
Video S1 from Stathmin Is Required for Normal Mouse Mammary Gland Development and Δ16HER2-Driven Tumorigenesis
Authors: Segatto Ilenia , Zompit Mara De Marco , Citron Francesca , D'Andrea Sara , Vinciguerra Gian Luca Rampioni , Perin Tiziana , Berton Stefania , Mungo Giorgia , Schiappacassi Monica , Marchini Cristina , Amici Augusto , Vecchione Andrea , Baldassarre Gustavo , Belletti Barbara
Published: April 2023

NMuMG CTR cells
Supplementary Data from Nanoparticle Encapsulation of Synergistic Immune Agonists Enables Systemic Codelivery to Tumor Sites and IFNβ-Driven Antitumor Immunity
Authors: Atukorale Prabhani U. , Raghunathan Shruti P. , Raguveer Vanitha , Moon Taylor J. , Zheng Carolyn , Bielecki Peter A. , Wiese Michelle L. , Goldberg Amy L. , Covarrubias Gil , Hoimes Christopher J. , Karathanasis Efstathios
Published: April 2023

SF1: IFNβ production from macrophages by ELISA analysis; SF2: FMT imaging of mammary tumors ex vivo for spatial localization of nanoparticle; SF3: Confocal micrographs of DiI-nanoparticle fluorescence in mammary tumor tissue; SF4: Representative images of tumor masses 4 days post-treatment; SF5: Primary tumor bioluminescence and change in weight in 4T1 tumor-bearing mice; SF6: Confocal microscopy of a representative healthy lung section; SF7: Change in weight in B16F10 tumor-bearing mice
Supplementary Figure 4 from SUMO-Specific Protease 1 Is Critical for Myeloid-Derived Suppressor Cell Development and Function
Authors: Huang Xian , Zuo Yong , Wang Xiuzhi , Wu Xuefeng , Tan Hongsheng , Fan Qiuju , Dong Baijun , Xue Wei , Chen Guo-Qiang , Cheng Jinke
Published: April 2023

SENP1 deficiency promotes MDSC expansion and suppression
Supplementary Figure 2 from SUMO-Specific Protease 1 Is Critical for Myeloid-Derived Suppressor Cell Development and Function
Authors: Huang Xian , Zuo Yong , Wang Xiuzhi , Wu Xuefeng , Tan Hongsheng , Fan Qiuju , Dong Baijun , Xue Wei , Chen Guo-Qiang , Cheng Jinke
Published: April 2023

SENP1 deficiency promotes tumor metastasis
Microfluidics chip based exosome proteomic profiling from A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer
Authors: Dorayappan Kalpana Deepa Priya , Gardner Miranda L. , Hisey Colin L. , Zingarelli Roman A. , Smith Brentley Q. , Lightfoot Michelle D.S. , Gogna Rajan , Flannery Meghan M. , Hays John , Hansford Derek J. , Freitas Michael A. , Yu Lianbo , Cohn David E. , Selvendiran Karuppaiyah
Published: April 2023

Supplementory Materials and Methods for Microfluidic chip based exosome proteomic profiling
Supplementary Table 1 from CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC
Authors: Becker Jeffrey H. , Gao Yandi , Soucheray Margaret , Pulido Ines , Kikuchi Eiki , Rodríguez María L. , Gandhi Rutu , Lafuente-Sanchis Aranzazu , Aupí Miguel , Alcácer Fernández-Coronado Javier , Martín-Martorell Paloma , Cremades Antonio , Galbis-Caravajal José M. , Alcácer Javier , Christensen Camilla L. , Simms Patricia , Hess Ashley , Asahina Hajime , Kahle Michael P. , Al-Shahrour Fatima , Borgia Jeffrey A. , Lahoz Agustín , Insa Amelia , Juan Oscar , Jänne Pasi A. , Wong Kwok-Kin , Carretero Julian , Shimamura Takeshi
Published: April 2023

Supplementary Table 1
Supplementary Methods from Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma
Authors: Allen-Petersen Brittany L. , Risom Tyler , Feng Zipei , Wang Zhiping , Jenny Zina P. , Thoma Mary C. , Pelz Katherine R. , Morton Jennifer P. , Sansom Owen J. , Lopez Charles D. , Sheppard Brett , Christensen Dale J. , Ohlmeyer Michael , Narla Goutham , Sears Rosalie C.
Published: April 2023

Viability assays, Soft agar, Immunoprecipitation, Kinase inhibitor screen, and Patient outcome data
Supplemental Table 2 Phosphokinase Array from Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma
Authors: Allen-Petersen Brittany L. , Risom Tyler , Feng Zipei , Wang Zhiping , Jenny Zina P. , Thoma Mary C. , Pelz Katherine R. , Morton Jennifer P. , Sansom Owen J. , Lopez Charles D. , Sheppard Brett , Christensen Dale J. , Ohlmeyer Michael , Narla Goutham , Sears Rosalie C.
Published: April 2023

Results of the Phosphokinase Array with phosphorylation sites, fold change relative to vehicle, and Kmeans clustering.
Supplementary Data from Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus
Authors: Kennedy Barry E. , Murphy John Patrick , Clements Derek R. , Konda Prathyusha , Holay Namit , Kim Youra , Pathak Gopal P. , Giacomantonio Michael A. , Hiani Yassine El , Gujar Shashi
Published: April 2023

Supplemental figures 1-6 contain metabolomic, proteomic, extracellular flux analysis, cell death, and in vivo data supporting our findings that pyruvate dehydrogenase activity influences oncolytic viral therapy.
Supplemental Table 1 Kinase Inhibitor Screen from Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma
Authors: Allen-Petersen Brittany L. , Risom Tyler , Feng Zipei , Wang Zhiping , Jenny Zina P. , Thoma Mary C. , Pelz Katherine R. , Morton Jennifer P. , Sansom Owen J. , Lopez Charles D. , Sheppard Brett , Christensen Dale J. , Ohlmeyer Michael , Narla Goutham , Sears Rosalie C.
Published: April 2023

Results of Kinase Inhibitor Screen including compound names, IC50s, and fold change compared to vehicle.
Supplementary Data from Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus
Authors: Kennedy Barry E. , Murphy John Patrick , Clements Derek R. , Konda Prathyusha , Holay Namit , Kim Youra , Pathak Gopal P. , Giacomantonio Michael A. , Hiani Yassine El , Gujar Shashi
Published: April 2023

Supplementary Figure Legends
Supplementary Table S6 from Multiparametric MRI and Coregistered Histology Identify Tumor Habitats in Breast Cancer Mouse Models
Authors: Jardim-Perassi Bruna V. , Huang Suning , Dominguez-Viqueira William , Poleszczuk Jan , Budzevich Mikalai M. , Abdalah Mahmoud A. , Pillai Smitha R. , Ruiz Epifanio , Bui Marilyn M. , Zuccari Debora A.P.C. , Gillies Robert J. , Martinez Gary V.
Published: April 2023

Similarity index based on the weighted moving/sliding window was used to quantify the agreement for all wrong classifications between the habitats-map derived from MRI (5-parameters) and histology. The correct habitats from histological maps were compared with incorrect habitats from MRI maps. Thus, there were 9 incorrect classifications for maps containing V, H1, H2 and N, and 2 incorrect classifications for maps containing V, combined H1 + H2 and N to compare. The total average score for all wrong classifications for each sample is also shown in Supplementary Table 5.
Supplementary Data from Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus
Authors: Kennedy Barry E. , Murphy John Patrick , Clements Derek R. , Konda Prathyusha , Holay Namit , Kim Youra , Pathak Gopal P. , Giacomantonio Michael A. , Hiani Yassine El , Gujar Shashi
Published: April 2023

Raw values for all in vitro and in vivo metabolomic experiments are presented in supplemental tables 1, 7, and 8. Supplemental tables 2, 3, 4, and 5 contain the correlation values and enrichment analysis for all experiments. Supplemental table 6 contains raw values for 11-plex TMT proteomics experiment.
Supplementary Table S4 from Multiparametric MRI and Coregistered Histology Identify Tumor Habitats in Breast Cancer Mouse Models
Authors: Jardim-Perassi Bruna V. , Huang Suning , Dominguez-Viqueira William , Poleszczuk Jan , Budzevich Mikalai M. , Abdalah Mahmoud A. , Pillai Smitha R. , Ruiz Epifanio , Bui Marilyn M. , Zuccari Debora A.P.C. , Gillies Robert J. , Martinez Gary V.
Published: April 2023

Comparison of each MRI-parameter voxel values for MRI-habitat maps created by clustering 5 parameters (T2-map, T2*-map, Slope, Area under the curve (AUC) and time to max (TTM)) between habitats (clusters) using One-way analysis of variance (ANOVA) followed by the Tukey test for comparison.
Supplementary Table S3 from Multiparametric MRI and Coregistered Histology Identify Tumor Habitats in Breast Cancer Mouse Models
Authors: Jardim-Perassi Bruna V. , Huang Suning , Dominguez-Viqueira William , Poleszczuk Jan , Budzevich Mikalai M. , Abdalah Mahmoud A. , Pillai Smitha R. , Ruiz Epifanio , Bui Marilyn M. , Zuccari Debora A.P.C. , Gillies Robert J. , Martinez Gary V.
Published: April 2023

Comparison of each MRI-parameter voxel values (T2-map, T2*-map, Apparent diffusion coefficient (ADC), Slope, Area under the curve (AUC) and time to max (TTM)) between habitats (clusters) using One-way analysis of variance (ANOVA) followed by the Tukey test for comparison.
Table S1 from Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression
Authors: Wettersten Hiromi I. , Weis Sara M. , Pathria Paulina , Von Schalscha Tami , Minami Toshiyuki , Varner Judith A. , Cheresh David A.
Published: April 2023

Supplementary methods, including CRISPR sequences and antibodies
Figure S4 from Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression
Authors: Wettersten Hiromi I. , Weis Sara M. , Pathria Paulina , Von Schalscha Tami , Minami Toshiyuki , Varner Judith A. , Cheresh David A.
Published: April 2023

Supplementary data, including additional antibody-mediated killing assays and confirmation of integrin avb3 expression by flow cytometry.
Supplementary Figure 1 from Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell–Cell Biophysical Properties in Prostate Cancer
Authors: Rubenstein Cynthia S. , Gard Jaime M.C. , Wang Mengdie , McGrath Julie E. , Ingabire Nadia , Hinton James P. , Marr Kendra D. , Simpson Skyler J. , Nagle Raymond B. , Miranti Cindy K. , Warfel Noel A. , Garcia Joe G.N. , Arif-Tiwari Hina , Cress Anne E.
Published: April 2023

Muscle Invasive Networks in Aggressive Human Prostate Cancer
Figure S3 from LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY
Authors: Zhang Rui , Zhang Fan , Sun Zeguo , Liu Pengpeng , Zhang Xiao , Ye Yingnan , Cai Beiqi , Walsh Martin J. , Ren Xiubao , Hao Xishan , Zhang Weijia , Yu Jinpu
Published: April 2023

The association of (A) LINE-1 RTs / (B) immunocyte counts with smoking levels.
Figure S2 from LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY
Authors: Zhang Rui , Zhang Fan , Sun Zeguo , Liu Pengpeng , Zhang Xiao , Ye Yingnan , Cai Beiqi , Walsh Martin J. , Ren Xiubao , Hao Xishan , Zhang Weijia , Yu Jinpu
Published: April 2023

The OS was compared between patients with high and low expression of other LINE-1 RTs grouped according to mRNA levels.
Table S1 from Epigenetic Regulation of NAMPT by NAMPT-ASDrives Metastatic Progression in Triple-Negative Breast Cancer
Authors: Zhang Hanwen , Zhang Ning , Liu Ying , Su Peng , Liang Yiran , Li Yaming , Wang Xiaolong , Chen Tong , Song Xiaojin , Sang Yuting , Duan Yi , Zhang Jiashu , Wang Lijuan , Chen Bing , Zhao Wenjing , Guo Haiyang , Liu Zhaojian , Hu Guohong , Yang Qifeng
Published: April 2023

Primer information
Supplementary Figures from Epigenetic Regulation of NAMPT by NAMPT-ASDrives Metastatic Progression in Triple-Negative Breast Cancer
Authors: Zhang Hanwen , Zhang Ning , Liu Ying , Su Peng , Liang Yiran , Li Yaming , Wang Xiaolong , Chen Tong , Song Xiaojin , Sang Yuting , Duan Yi , Zhang Jiashu , Wang Lijuan , Chen Bing , Zhao Wenjing , Guo Haiyang , Liu Zhaojian , Hu Guohong , Yang Qifeng
Published: April 2023

The file contains 9 supplementary Figures indicating the bioinformatics analysis, transfection efficiency analysis, rescue experiments and clinical sample analysis.
sFigure 3 from KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop
Authors: Fujimura Ken , Wang Huawei , Watson Felicia , Klemke Richard L.
Published: April 2023

Role of eIF5A in regulation of Ras mRNA expression in pancreatic cells.
sFigure 2 from KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop
Authors: Fujimura Ken , Wang Huawei , Watson Felicia , Klemke Richard L.
Published: April 2023

Targeting eIF5A inhibits KRas expression and PDAC cell growth
Supplemental Figures and Tables from A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells
Authors: Truong Danh D. , Kratz Alexander , Park Jin G. , Barrientos Eric S. , Saini Harpinder , Nguyen Toan , Pockaj Barbara , Mouneimne Ghassan , LaBaer Joshua , Nikkhah Mehdi
Published: April 2023

Figure S1-3 describes characterization of patient-derived fibroblasts. Figure S4-5 describes influence of cancer-associated fibroblasts on cancer cell invasion. Figure S6 provides additional details on GPNMB clinical relevance. Figure S7 validates GPNMB expression. Figure S8 confirms GPNMB knockdown. Figure S9 and 10 demonstrates effect of GPNMB knockdown in MDA-MB-231 and overexpression in MCF7 cells. Movie S1 and S2 compares migration of cancer cells with and without CAFs. Movie S3 and S4 compares migration of CAFs with and without cancer cells. Movie S5 and S6 shows effect of GPNMB knockdown. Table S1 describes characterization of patients. Table S2 and S3 describes profiling of transcriptome in SUM-159 co-cultures. Tables S4 and S5 describes profiling of transcriptome in SUM-159 NF co-culture. Tables S6 and S7 describes profiling of transcriptome in SUM-159 CAF co-culture. Table S8 is a list of differentially expressed genes between CAF and NF co-cultures. Table S9 is a list of migration/metastasis-related differentially expressed genes associated with GPNMB.
Supplementary Tables 1-3. from TTPAL Promotes Colorectal Tumorigenesis by Stabilizing TRIP6 to Activate Wnt/β-Catenin Signaling
Authors: Gou Hongyan , Liang Jessie Qiaoyi , Zhang Lijing , Chen Huarong , Zhang Yanquan , Li Rui , Wang Xiaohong , Ji Jiafu , Tong Joanna H. , To Ka-Fai , Sung Joseph J.Y. , Chan Francis K.L. , Fang Jing-Yuan , Yu Jun
Published: April 2023

Supplementary Table 1. Antibodies used in this study. Supplementary Table 2. Clinicopathologic features of TTPAL mRNA expression with CRC from Chinese cohort 1and protein expression with CRC from Chinese cohort 2. Supplementary Table 3. The list of potential target genes of TTPAL identified by LC-MS.
Movie S5 from A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells
Authors: Truong Danh D. , Kratz Alexander , Park Jin G. , Barrientos Eric S. , Saini Harpinder , Nguyen Toan , Pockaj Barbara , Mouneimne Ghassan , LaBaer Joshua , Nikkhah Mehdi
Published: April 2023

Time-lapse imaging of shCtrl line migrating through the 3D stroma.
Supplementary Figures 1-5. from TTPAL Promotes Colorectal Tumorigenesis by Stabilizing TRIP6 to Activate Wnt/β-Catenin Signaling
Authors: Gou Hongyan , Liang Jessie Qiaoyi , Zhang Lijing , Chen Huarong , Zhang Yanquan , Li Rui , Wang Xiaohong , Ji Jiafu , Tong Joanna H. , To Ka-Fai , Sung Joseph J.Y. , Chan Francis K.L. , Fang Jing-Yuan , Yu Jun
Published: April 2023

Supplementary Figure 1. Screening of TTPAL by whole genome sequencing and TTPAL amplification validation in CRC. Supplementary Figure 2. TTPAL effects on signaling pathway. Supplementary Figure 3. TRIP6 was highly expressed in CRC. Supplementary Figure 4. TRIP6 showed oncogenic function in CRC. Supplementary Figure 5. MAGI1 showed tumor suppressor function in CRC.
Movie S2 from A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells
Authors: Truong Danh D. , Kratz Alexander , Park Jin G. , Barrientos Eric S. , Saini Harpinder , Nguyen Toan , Pockaj Barbara , Mouneimne Ghassan , LaBaer Joshua , Nikkhah Mehdi
Published: April 2023

Time-lapse imaging of SUM-159 breast cancer cells migrating through the 3D stroma in presence of CAFs.
Figure S7 from The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3
Authors: Gambi Giovanni , Di Simone Elisabetta , Basso Veronica , Ricci Luisa , Wang Rui , Verma Akanksha , Elemento Olivier , Ponzoni Maurilio , Inghirami Giorgio , Icardi Laura , Mondino Anna
Published: April 2023

Data depict the role of Sirtuin 1 and DNMT, HDAC and PI3K inhibition on Stat3 acetylation and TSG expression.
Supplementary Tables from Anthropometric Risk Factors for Cancers of the Biliary Tract in the Biliary Tract Cancers Pooling Project
Authors: Jackson Sarah S. , Van Dyke Alison L. , Zhu Bin , Pfeiffer Ruth M. , Petrick Jessica L. , Adami Hans-Olov , Albanes Demetrius , Andreotti Gabriella , Beane Freeman Laura E. , Berrington de González Amy , Buring Julie E. , Chan Andrew T. , Chen Yu , Fraser Gary E. , Freedman Neal D. , Gao Yu-Tang , Gapstur Susan M. , Gaziano J. Michael , Giles Graham G. , Grant Eric J. , Grodstein Francine , Hartge Patricia , Jenab Mazda , Kitahara Cari M. , Knutsen Synnove F. , Koh Woon-Puay , Larsson Susanna C. , Lee I-Min , Liao Linda M. , Luo Juhua , McGee Emma E. , Milne Roger L. , Monroe Kristine R. , Neuhouser Marian L. , O’Brien Katie M. , Peters Ulrike , Poynter Jenny N. , Purdue Mark P. , Robien Kim , Sandler Dale P. , Sawada Norie , Schairer Catherine , Sesso Howard D. , Simon Tracey G. , Sinha Rashmi , Stolzenberg-Solomon Rachael Z. , Tsugane Shoichiro , Wang Renwei , Weiderpass Elisabete , Weinstein Stephanie J. , White Emily , Wolk Alicja , Yuan Jian-Min , Zeleniuch-Jacquotte Anne , Zhang Xuehong , McGlynn Katherine A. , Campbell Peter T. , Koshiol Jill
Published: April 2023

This file contains Supplementary tables 1 - 7 and the text for Supplementary Figure 1A-D.
Supplementary Figures from HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance
Authors: Liu Shou , Lee Ji Shin , Jie Chunfa , Park Min Ho , Iwakura Yoichiro , Patel Yogin , Soni Mithil , Reisman David , Chen Hexin
Published: April 2023

Supplementary Figures with legends- Supplementary Figures S1 to S14. S1. Shows gene ontology enrichment analysis between MCF10A-HER2 and MCF10A-vector cells. S2 shows western blot analysis of HER2 signaling after IL-1β treatment. S3, S4 and S9 show knockout of IL1A and IL6 using CRISPR/Cas9 system. S5 shows western blot analysis of HER2-signalign pathways in cells treated with IRAK1 and JAK2 inhibitors. S6 shows that activation of NF-κB and STAT3 is not mediated by HER2-immediate downstream molecules. S7 and S10 shows western blot analysis of total HER2, phosphorylated p65, STAT3 and AKT in mammary gland tissues and primary tumors. S8 shows the effects of blockades of HER2-downstream signaling pathways on cell viability. S11 shows representative images of Immunohistochemical staining of HER2, IL-1α and IL6 in primary breast cancer tissues. S12 shows Kaplan-Meier plots of distant metastasis-free survival of patients. S13 shows combination drug effects of IRAK inhibitor (IRAKi) plus paclitaxel (PCL) or cisplatin (CPT). S14 shows tumor volume growth curves for individual mice after last treatment.
Supplementary Data from The HPV16 Genome Is Stable in Women Who Progress to In Situ or Invasive Cervical Cancer: A Prospective Population-Based Study
Authors: Arroyo-Mühr Laila-Sara , Lagheden Camilla , Hultin Emilie , Eklund Carina , Adami Hans-Olov , Dillner Joakim , Sundström Karin
Published: April 2023

Supplementary Table 2: Substitution rate in substitutions/site/year by quartile of follow-up time in months
Supplementary Data from The HPV16 Genome Is Stable in Women Who Progress to In Situ or Invasive Cervical Cancer: A Prospective Population-Based Study
Authors: Arroyo-Mühr Laila-Sara , Lagheden Camilla , Hultin Emilie , Eklund Carina , Adami Hans-Olov , Dillner Joakim , Sundström Karin
Published: April 2023

Supplementary Table 3. SNPs in serial smears
Supplemental Table from MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes
Authors: Casadei Lucia , Calore Federica , Braggio Danielle A. , Zewdu Abeba , Deshmukh Ameya A. , Fadda Paolo , Lopez Gonzalo , Wabitsch Martin , Song Chi , Leight Jennifer L. , Grignol Valerie P. , Lev Dina , Croce Carlo M. , Pollock Raphael E.
Published: April 2023

Supplemental Tables are: ST1: Detailed information about DDLPS patients; ST2: Detailed information about healthy control; ST3: MDM2 primer sequences; ST4: DDLPS patients information; ST5: Healthy control clinical information; ST6: RT-PCR quality control on isolated EVs; ST7: Cell cycle distribution analysis regarding P-a incubated with Lipo246-EVs; ST8: Additional DDLPS patients information; ST9: Additional healthy control clinical information.
Figure S2 from SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program
Authors: Oliphant Michael U.J. , Vincent Melanie Y. , Galbraith Matthew D. , Pandey Ahwan , Zaberezhnyy Vadym , Rudra Pratyaydipta , Johnson Katherine R. , Costello James C. , Ghosh Debashis , DeGregori James , Espinosa Joaquin M. , Ford Heide L.
Published: April 2023

Six2 OE leads to a change in the transcriptional program of 4T07 cells and differential expression of stemness-related genes and pathways