bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical Simulation of Time-Varying Characteristics in a High-Permeability Sandstone Reservoir: A Case of Gaoqian Southern Area
Authors: Xu Hui , Cheng Guofeng , Liu Nannan , Wang Lizhi , Guo Zhenghuai , Wang Xiang , Dou Xiangji , Li Juan , Chen Shangping , Shi Xing
Published: April 2024

In the process of long-term water flooding in the Gaoqian Southern Area with an average porosity of 30% and an average permeability of 1333.5×10−3 μm2, the fluid-solid interaction among oil, water, and rock has a great influence on the pore structure. It has resulted in changes in reservoir parameters with the extension of time. This paper used electron microscopy scanning, mercury injection, X-ray diffraction, physical properties, and oil-water relative permeability curves to study the variation of clay mineral content, pore throat structure, porosity, permeability, and relative permeability curves of high-permeability sandstone after high-pressure water flooding. The results showed that clay minerals such as montmorillonite and kaolinite were dissolved, hydrated, and migrated after long-term water flooding, which resulted in the decrease of clay mineral content in fine sandstone and medium sandstone, the increase of pore throat radius, and the decrease of displacement pressure, median pressure, and separation coefficient. The saturation of the isotonic point of the oil-water relative permeability curve was obviously shifted to the right, the hydrophilicity was significantly enhanced, and the porosity and permeability were effectively improved, but there was a blockage of the throat less than 2 μm in the fine sandstone. In addition, this paper established the equations of water injection, permeability, irreducible water saturation, residual oil saturation, and oil-water relative permeability curve coefficient and establishes the initial permeability model with the well data before water flooding. The logging interpretation results of development wells in the process of water flooding as verification data were used, and the relative error of permeability far lower than the general requirement of permeability error within an order of magnitude was less than 30%, which verified the rationality of the method.
What Influences Patients Readiness for Discharge: The Case of Total Knee Arthroplasty: A Cross-Sectional Study
Authors: Li Na , Moreira Paulo , Guo Manjie , You Simeng , Dsouza Brayal , Ji Hong
Published: April 2024

Aims and Objectives. To identify and explore assess factors that influence patients’ readiness for hospital discharge (RHD) after total knee arthroplasty (TKA). Background. Evidence has suggested that most clinical staff use clinical laboratory indicators to determine discharge times, while paying little attention to patients’ feelings and needs. Additional research findings have suggested a relationship between patients’ self-reported readiness for hospital discharge and postdischarge complication rates, readmission rates, mortality, as well as quality of life. RHD is strongly associated with patient health outcomes. Identifying relevant influencing factors can provide guidance for early individualized interventions by healthcare professionals. Design. A cross-sectional study. Methods. During 2022, a total of 320 post-TKA patients were selected for this study. The patients were divided into the low-RHD group (<7 points) and the high-RHD group (≥7 points) according to the mean score of the Readiness for Hospital Discharge Scale (RHDS). Established scales were used to collect patients’ information and to adopt univariate and binary logistic regression analysis to screen for independent factors. Results. In this study, the RHDS score of patients after TKA is 91.90 ± 7.05, of which 12.8% are in the low-RHD group (mean score <7). The binary logistic regression results reveal that age, educational level, postactivity pain, self-efficacy, and family care have to be considered risk factors generating low-RHD in TKA patients. Conclusions. The present study suggests that over 1/8 TKA patients are not ready at the time of discharge. Physicians and nurses can improve patients’ RHD by reducing postactivity pain and improving self-efficacy during their rehabilitation period. Relevance to Clinical Practice. The results of this study can help physicians and nurses early identify high-risk patients with low RHD and provide them with individualized interventions. In addition to this, it is important that nurses use RHDS to assess the readiness of TKA patients before they are discharged from the hospital.
Prevalence of Hepatitis B Viral Infection in Pregnant Women at the Suhum Municipality, Ghana
Authors: Boachie Joseph , Pidah Doreen , Eshun Henrietta , Jingbeja Emmanuel , Adjei Praise Fosu , Adu Patrick
Published: April 2024

Background. Global prevalence of chronic hepatitis B virus (HBV) infection was estimated between 257 and 291 million since 2020, posing a great public health challenge. In Africa, an estimated 60 million cases of HBV were reported in the same year. Pregnant women might be susceptible to HBV infection dependent on their level of awareness and knowledge about the causes, transmission, and prevention of HBV. The aim of the study was to assess the awareness and prevalence of HBV infection and prolonged bleeding risk among pregnant women at the Suhum Municipality of Ghana. Methods. The study was a cross-sectional design involving pregnant women who were sampled following their visit to the antenatal unit at the Suhum Government Hospital. Sociodemographics including history of HBV screening and vaccinations were obtained from consented individuals using pretested questionnaires. Also, venous blood samples were obtained for platelet count, whereas bleeding time assay was performed to assess functional platelet disorders. Results. Hepatitis B prevalence was 4.4%, with 14.1% prevalence of mild thrombocytopenia and 1.5% prevalence of prolonged bleeding time. Pregnant women who had tertiary education and previous screening were about 8 times (AOR=7.78, 95% CI: 1.50-40.50) and 14 times (AOR=13.66, 95% CI: 1.72-108.75) more likely to have knowledge of hepatitis B than those without tertiary education and previous screening, respectively. Conclusion. The prevalence of HBV was 4.4%. Education status and previous screening were associated with demonstration of knowledge about HBV; therefore, intensification of education and screening are recommended.
Supplementary Figure 3 from Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non–Small Cell Lung Cancer
Authors: Rigamonti Alessandra , Viatore Marika , Polidori Rebecca , Rahal Daoud , Erreni Marco , Fumagalli Maria Rita , Zanini Damiano , Doni Andrea , Putignano Anna Rita , Bossi Paola , Voulaz Emanuele , Alloisio Marco , Rossi Sabrina , Zucali Paolo Andrea , Santoro Armando , Balzano Vittoria , Nisticò Paola , Feuerhake Friedrich , Mantovani Alberto , Locati Massimo , Marchesi Federica
Published: April 2024

Supplementary Figure 3
Supplemental Table S4 from Subclonal Cancer Driver Mutations Are Prevalent in the Unresected Peritumoral Edema of Adult Diffuse Gliomas
Authors: Underhill Hunter R. , Karsy Michael , Davidson Christian J. , Hellwig Sabine , Stevenson Samuel , Goold Eric A. , Vincenti Sydney , Sellers Drew L. , Dean Charlie , Harrison Brion E. , Bronner Mary P. , Colman Howard , Jensen Randy L.
Published: April 2024

Supplemental Table S4. Truth set of single nucleotide variants in HD701 DNA and associated dilutions.
Supplementary Figure S4 from Human Tumor–Associated Macrophages and Neutrophils Regulate Antitumor Antibody Efficacy through Lethal and Sublethal Trogocytosis
Authors: Singhal Sunil , Rao Abhishek S. , Stadanlick Jason , Bruns Kyle , Sullivan Neil T. , Bermudez Andres , Honig-Frand Adam , Krouse Ryan , Arambepola Sachinthani , Guo Emily , Moon Edmund K. , Georgiou George , Valerius Thomas , Albelda Steven M. , Eruslanov Evgeniy B.
Published: April 2024

Supplementary Figure S4. (A) Cumulative results showing the kinetics of GFP+A431 tumor cell growth when co-cultured with PBN isolated from lung cancer patients at 50:1 E:T ratio in the presence of cetuximab (IgG) and IgA anti-EGFR Ab (IgA) using the IncuCyte® Live Cell Analysis System. One-way ANOVA with Turkey’s multiple comparisons test. Number of patients included in each analysis is indicated on the graphs. All data represented as mean ± SEM. (B) Cumulative results showing the kinetics of GFP+A431 tumor cell growth when co-cultured with blood and tumor FcR+ effectors for 48 hrs at 50:1 E:T ratio in the presence of IgA2 isotype control Abs in the IncuCyte® Live Cell Analysis System. One-way ANOVA with Dunnett's multiple comparisons test. All data represented as mean ± SEM. (C) Representative dotplots showing ADT mediated by TAM pretreated with cytohalasin D (1uM) or blocking anti-CD64 F(ab')2 and anti-CD32 F(ab')2 fragments (5ug/ml). TAM were co-cultured with PKH67+ A431 cells at a ratio 3:1 in the presence of cetuximab (1ug/ml) for 2 hrs. (D) Cumulative flow cytometry results showing the trogocytosis mediated by indicated blood and tumor myeloid effectors co-cultured with PKH67+A431 cells for 12 hrs at a 50:1 E:T ratio in the presence of IgG1 and IgA2 isotype control Abs (1ug/ml). Indicated FcR+ effectors were freshly isolated for all experiments.
Supplementary Fig.S5 from PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer
Authors: Yamamoto Takehiro , Hayashida Tetsu , Masugi Yohei , Oshikawa Kiyotaka , Hayakawa Noriyo , Itoh Mai , Nishime Chiyoko , Suzuki Masami , Nagayama Aiko , Kawai Yuko , Hishiki Takako , Matsuura Tomomi , Naito Yoshiko , Kubo Akiko , Yamamoto Arisa , Yoshioka Yujiro , Kurahori Tomokazu , Nagasaka Misa , Takizawa Minako , Takano Naoharu , Kawakami Koji , Sakamoto Michiie , Wakui Masatoshi , Yamamoto Takushi , Kitagawa Yuko , Kabe Yasuaki , Horisawa Kenichi , Suzuki Atsushi , Matsumoto Masaki , Suematsu Makoto
Published: April 2024

Fig.S5
Figure S2 from Immunometabolic Adaptation of CD19-Targeted CAR T Cells in the Central Nervous System Microenvironment of Patients Promotes Memory Development
Authors: Goldberg Lior , Haas Eric R. , Urak Ryan , Vyas Vibhuti , Pathak Khyatiben V. , Garcia-Mansfield Krystine , Pirrotte Patrick , Singhal Jyotsana , Figarola James L. , Aldoss Ibrahim , Forman Stephen J. , Wang Xiuli
Published: April 2024

Figure S2. Spatiotemporal cytokines analysis.
Supplementary Information 1 from Combined Vorinostat and Chloroquine Inhibit Sodium–Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo
Authors: Read Martin L. , Brookes Katie , Zha Ling , Manivannan Selvambigai , Kim Jana , Kocbiyik Merve , Fletcher Alice , Gorvin Caroline M. , Firth George , Fruhwirth Gilbert O. , Nicola Juan P. , Jhiang Sissy , Ringel Matthew D. , Campbell Moray J. , Sunassee Kavitha , Blower Philip J. , Boelaert Kristien , Nieto Hannah R. , Smith Vicki E. , McCabe Christopher J.
Published: April 2024

This file contains Supplementary Materials and Methods, as well as Supplementary References.
Supplementary Figure S9 from Combined Vorinostat and Chloroquine Inhibit Sodium–Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo
Authors: Read Martin L. , Brookes Katie , Zha Ling , Manivannan Selvambigai , Kim Jana , Kocbiyik Merve , Fletcher Alice , Gorvin Caroline M. , Firth George , Fruhwirth Gilbert O. , Nicola Juan P. , Jhiang Sissy , Ringel Matthew D. , Campbell Moray J. , Sunassee Kavitha , Blower Philip J. , Boelaert Kristien , Nieto Hannah R. , Smith Vicki E. , McCabe Christopher J.
Published: April 2024

Supplementary Figure S9
Supplementary Figure S1 from Enhancer of Zeste Homolog 2 Inhibitor SHR2554 in Relapsed or Refractory Peripheral T-cell Lymphoma: Data from the First-in-Human Phase I Study
Authors: Song Yuqin , Jin Zhengming , Li Zhi-Ming , Liu Yanyan , Li Lanfang , He Chuan , Su Hang , Zhou Hui , Li Kunyan , Hao Siguo , Zuo Xuelan , Wu Jianyuan , Li Dengju , Wu Meng , Sun Xiuhua , Qi Junyuan , Cai Zhen , Li Zengjun , Li Yijing , Huang Yanhua , Shen Jie , Xiao Zhenyu , Zhu Jun
Published: April 2024

Supplementary Figure S1. Progression-free survival by lymphoma subtype.
Supplementary Table S1 from Sensitive MRD Detection from Lymphatic Fluid after Surgery in HPV-Associated Oropharyngeal Cancer
Authors: Earland Noah , Semenkovich Nicholas P. , Ramirez Ricardo J. , Gerndt Sophie P. , Harris Peter K. , Gu Zhuosheng , Hearn Andrew I. , Inkman Matthew , Szymanski Jeffrey J. , Whitfield Damion , Wahle Benjamin M. , Xu Zhongping , Chen Kevin , Alahi Irfan , Ni Gabris , Chen Andrew , Winckler Wendy , Zhang Jin , Chaudhuri Aadel A. , Zevallos Jose P.
Published: April 2024

Supplementary Table S1. Patient-level characteristics of the HPV (+) OPSCC cohort
Supplementary tables 1 from Trastuzumab and Pertuzumab in Patients with Non-Breast/Gastroesophageal HER2-Amplified Tumors: Results from the NCI–MATCH ECOG–ACRIN Trial (EAY131) Subprotocol J
Authors: Connolly Roisin M. , Wang Victoria , Hyman David M. , Grivas Petros , Mitchell Edith P. , Wright John J. , Sharon Elad , Gray Robert J. , McShane Lisa M. , Rubinstein Larry V. , Patton David R. , Williams P. Mickey , Hamilton Stanley R. , Wang Jue , Wisinski Kari B. , Tricoli James V. , Conley Barbara A. , Harris Lyndsay N. , Arteaga Carlos L. , O'Dwyer Peter J. , Chen Alice P. , Flaherty Keith T.
Published: April 2024

Supplementary tables
Supplementary Table S4 from Combining Genomic Biomarkers to Guide Immunotherapy in Non–Small Cell Lung Cancer
Authors: van de Haar Joris , Mankor Joanne M. , Hummelink Karlijn , Monkhorst Kim , Smit Egbert F. , Wessels Lodewyk F.A. , Cuppen Edwin , Aerts Joachim G.J.V. , Voest Emile E.
Published: April 2024

Actionable EGFR alterations, TMB and DCB in the validation cohort.
Supplementary Figure S4 from Combining Genomic Biomarkers to Guide Immunotherapy in Non–Small Cell Lung Cancer
Authors: van de Haar Joris , Mankor Joanne M. , Hummelink Karlijn , Monkhorst Kim , Smit Egbert F. , Wessels Lodewyk F.A. , Cuppen Edwin , Aerts Joachim G.J.V. , Voest Emile E.
Published: April 2024

Alterations in STK11, KEAP1, or EGFR and survival of TMB-based subgroups in the validation cohort.
Supplementary Table S6 from Dual-Hit Strategy for Therapeutic Targeting of Pancreatic Cancer in Patient-Derived Xenograft Tumors
Authors: Roy Chaudhuri Tista , Lin Qingxiang , Stachowiak Ewa K. , Rosario Spencer R. , Spernyak Joseph A. , Ma Wen Wee , Stachowiak Michal K. , Greene Michelle K. , Quinn Gerard P. , McDade Simon S. , Clynes Martin , Scott Christopher J. , Straubinger Robert M.
Published: April 2024

Supplementary Table S6. Results of transcription factor enrichment analysis of PDX tumor #18269
Data from Enhancer of Zeste Homolog 2 Inhibitor SHR2554 in Relapsed or Refractory Peripheral T-cell Lymphoma: Data from the First-in-Human Phase I Study
Authors: Song Yuqin , Jin Zhengming , Li Zhi-Ming , Liu Yanyan , Li Lanfang , He Chuan , Su Hang , Zhou Hui , Li Kunyan , Hao Siguo , Zuo Xuelan , Wu Jianyuan , Li Dengju , Wu Meng , Sun Xiuhua , Qi Junyuan , Cai Zhen , Li Zengjun , Li Yijing , Huang Yanhua , Shen Jie , Xiao Zhenyu , Zhu Jun
Published: April 2024

AbstractPurpose:
Patients with peripheral T-cell lymphomas (PTCL) in the relapsed or refractory (r/r) setting have only a limited number of therapies available, and the prognosis is extremely poor. SHR2554 is an oral inhibitor against EZH2, a rational therapeutic target for lymphomas.
Patients and Methods:
This was a multicenter, two-part, phase I study of SHR2554 in r/r mature lymphoid neoplasms. In part I, 350 mg twice daily was established as the recommended phase II dose (RP2D) based on the findings during dose escalation and expansion; subsequently, selected lymphoma subtypes were recruited in clinical expansion cohorts to receive SHR2554 at RP2D. Here, we provide an in-depth assessment of SHR2554 at RP2D in subpopulation with r/r PTCL.
Results:
Twenty-eight patients were included for analysis (17 angioimmunoblastic T-cell lymphoma and 11 not otherwise specified). Eighteen (64%) patients had received ≥2 lines of previous anticancer therapies. The objective response rate was 61% [95% confidence interval (CI), 41–78]. Responses were still ongoing in 59% (10/17) of the responders; estimated median duration of response was 12.3 months (95% CI, 7.4–not reached). Median progression-free survival was 11.1 months (95% CI, 5.3–22.0), and 12-month overall survival rate was 92% (95% CI, 72–98). The most common grade 3 or 4 treatment-related adverse events were decreased platelet count [nine (32%)] as well as decreased white blood cell count, decreased neutrophil count, and anemia [four (14%) for each]. No treatment-related deaths were reported.
Conclusions:
This extended follow-up analysis further supports SHR2554 as a therapeutic opportunity for patients with r/r PTCL.
Data from Phase II DORA Study of Olaparib with or without Durvalumab as a Chemotherapy-Free Maintenance Strategy in Platinum-Pretreated Advanced Triple-Negative Breast Cancer
Authors: Tan Tira J. , Sammons Sarah , Im Young-Hyuck , She Lilin , Mundy Kelly , Bigelow Robert , Traina Tiffany A. , Anders Carey , Yeong Joe , Renzulli Ezequiel , Kim Sung-Bae , Dent Rebecca
Published: April 2024

AbstractPurpose:
We explored the efficacy of PARP inhibition with or without programmed death ligand-1 (PD-L1) blockade as chemotherapy-free maintenance therapy for advanced triple-negative breast cancer (aTNBC) sensitive to platinum-based chemotherapy.
Patients and Methods:
In the phase II non-comparative DORA trial (NCT03167619), patients with ongoing stable disease (SD) or complete/partial response (CR/PR) to first- or second-line platinum-based chemotherapy for TNBC (≤10% estrogen/progesterone receptor expression) were randomized 1:1 to receive olaparib 300 mg twice daily with or without durvalumab 1,500 mg on day 1 every 4 weeks. The primary objective was to compare progression-free survival (PFS) versus a historical control of continued platinum-based therapy.
Results:
45 patients were randomized (23 to olaparib alone, 22 to the combination; 3 with estrogen/progesterone receptor expression 1%–10%). At 9.8 months’ median follow-up, median PFS from randomization was 4.0 [95% confidence interval (CI), 2.6–6.1] months with olaparib and 6.1 (95% CI, 3.7–10.1) months with the combination, both significantly longer than the historical control (P = 0.0023 and P < 0.0001, respectively). Clinical benefit rates (SD ≥24 weeks or CR/PR) were 44% (95% CI, 23%–66%) and 36% (95% CI, 17%–59%) in the monotherapy and combination arms, respectively. Sustained clinical benefit was seen irrespective of germline BRCA mutation or PD-L1 status, but tended to be associated with CR/PR to prior platinum, particularly in the olaparib-alone arm. No new safety signals were reported.
Conclusions:
PFS was longer than expected with both regimens. A patient subset with wild-type BRCA platinum-sensitive aTNBC had durable disease control with chemotherapy-free maintenance.
Inclusión, una mirada hacia la comprensión de las voces de los docentes
Authors: Agudelo Gomez Paula Andrea
Published: April 2024

El objetivo de este estudio es comprender las representaciones sociales de un grupo de docentes en relación a las prácticas pedagógicas y co-construir una propuesta para la construcción de paz desde un enfoque incluyente. Los participantes del estudio fueron 12 docentes de la Institución Educativa Sagrada Familia del De Municipio Puerto Tejada, Departamento del Cauca, quienes accedieron a brindar información en torno a las representaciones sociales sobre la discapacidad, y las prácticas Pedagógicas inclusivas; información que se recogió a partir de la entrevista semiestructurada, taller y diligenciamiento del formato público, plan individual de ajuste razonable, (PIAR).

El estudio se orientó bajo un enfoque cualitativo, responde al abordaje epistémico metodológico de la hermenéutica ontológica política, porque pretende dar cuenta de la comprensión de las narrativas de los docentes que participaron en este estudio. Se logró evidenciar la presencia de las barreras actitudinales como parte de las representaciones en cuanto a la discapacidad y las prácticas pedagógicas tradicionales, las cuales atañen a la poca participación. Como resultado se consolida la propuesta educativa de agenciamiento social, “proyecto de aula” denominado: re significando experiencias pedagógicas una apuesta para la construcción de paz, el cual se tuvo en cuenta los principios del Diseño Universal para el Aprendizaje, (DUA).
COVID-19 y estrategias económicas familiares: ¿cómo enfrentan las mujeres chilenas la vulnerabilidad en esta crisis?
Authors: Rodríguez Garcés Carlos , Ruiz Claudia , Padilla Geraldo 'Bladimir' , Espinosa Valenzuela Denisse
Published: April 2024

La propagación de la enfermedad por COVID-19 ha tenido una serie de repercusiones negativas sobre la salud de las personas, la estabilidad de las familias y la economía de los países. Este artículo analiza la situación de vulnerabilidad socioeconómica que afecta a las mujeres jefas de hogar en Chile debido a la pandemia, especialmente su situación laboral, de ingresos y gastos, teniendo como fuente la Encuesta Social COVID-19 (ESC-19) realizada durante el año 2020. Los resultados muestran que durante los últimos meses han decaído notoriamente los recursos entre las familias de jefatura femenina, hecho vinculado al desempleo, la presencia de hijos/as y ausencia de pareja, lo que ha presionado al uso de estrategias económicas para la generación de ingresos y la reducción de gastos, particularmente la descapitalización, el endeudamiento y la limitación del consumo de alimentos y servicios básicos. Las conclusiones enfatizan la necesidad por repensar la política pública en Chile, que actualmente se encuentra al alero de un modelo que privilegia la satisfacción de necesidades en relación al mercado y resulta poco eficiente para sostener la calidad de vida, problemática especialmente notoria en tiempos de crisis como la causada por la COVID-19.
El aprendizaje del lenguaje escrito mediante el arte. Un aporte desde los procesos sociales.
Authors: García Martínez Laura Viviana
Published: April 2024

Los procesos de exclusión derivados de las dificultades en el aprendizaje y desarrollo del lenguaje escrito representan una preocupación a nivel mundial, situación que plantea la necesidad de generar oportunidades partiendo de comprender el mismo como una práctica cultural y no solo como función exclusiva de las instituciones educativas. En este marco, tiene lugar a la presente investigación cualitativa, la cual buscó reconocer los aportes del arte y la cultura al aprendizaje del lenguaje escrito, en el marco de un proyecto social en una comunidad de niños, niñas y adolescentes en condición de desventaja. Esto a través de la investigación acción, empleando herramientas como la observación no participativa de 40 niños, niñas y adolescentes del barrio Juan Pablo II en la Localidad de Ciudad Bolívar, durante actividades artísticas; y la generación de conversaciones cordiales con los docentes de arte. El análisis de la información, permitió concluir que a través del arte en espacios sociales se desarrollan funciones a nivel cognitivo y lingüístico; así como, habilidades metalingüísticas y metacognitivas fundamentales para la adquisición y perfeccionamiento de la lectura y la escritura. Lo anterior, guarda relación con las habilidades histriónicas de los docentes de arte, la relación equilibrada entre docentes, niños, niñas y adolescentes y la integración del lenguaje escrito en actividades propias de su etapa de desarrollo, en ambientes naturales con una carga de emocionalidad positiva
Nivel económico-social familiar, escolar y contexto alfabetizador hogareño
Authors: Ferroni Marina
Published: April 2024

Este artículo de investigación se propuso indagar sobre el impacto del NES (nivel económico social) individual, escolar y el contexto alfabetizador hogareño en el proceso de alfabetización de un grupo de niños que crecen en contextos de pobreza.

A partir de un diseño cuantitativo no experimental de tipo transversal -correlacional, se evaluó a un grupo de 87 niños (entre los 8 y los 12 años) que vivían en barrios socialmente vulnerados con una prueba de escritura de palabras al dictado. Asimismo, se administró a las familias de los niños dos entrevistas para su contexto alfabetizador hogareño y su nivel económico social (NES). Como medida de NES escolar, se calculó la distancia entre los barrios de los niños del estudio y las escuelas a las que asistían.

Los resultados obtenidos señalan la existencia de asociaciones entre la escritura y el NES individual, escolar y el contexto alfabetizador hogareño.

Un análisis más profundo de los resultados señaló que el desempeño en escritura fue explicado mayormente por la medida de NES escolar de los niños.

Los datos presentados señalan un fuerte impacto de la calidad de las oportunidades educativas a las que se ven expuestos los niños que viven en contextos de pobreza.
Los usos de las TIC y la educomunicación en las propuestas que buscan la construcción de paz.
Authors: Tobón Múnera Verónica Marcela Tobón Múnera , López Montoya Helinson , Rivera González Wilson Andrés , Vásquez Velásquez Ana María , Londoño Vásquez David Alberto
Published: April 2024

El propósito de esta reflexión es un acercamiento a las prácticas o propuestas educomunicativas en entornos sociales y escolares que han orientado los procesos de construcción de la paz y de memoria histórica por medio del uso de diferentes tecnologías en las acciones educativas. Para el desarrollo, se crea una división a partir de los modos y medios abordados en las propuestas. Tales como: el papel de la música, de la imagen y de las redes sociales. Además, se analiza la forma cómo estos se han estado empleando en diferentes contextos. Se destaca el papel de la educomunicación, para dotar de criticidad a las acciones que se dan con el uso de medios y tecnologías, en pro de aprovechar sus potencialidades.
Fenomenologia: aplicações metodológicas em pesquisas sobre cidades
Authors: Giese Juliana Varejão , Silva Luciana Bosco e , Melo Caique de Souza
Published: April 2024

Despite the frequent use of phenomenology as a methodology in research on Geography, Anthropology, Sociology, Architecture and Urbanism, there is still a preambular use of the terminology "urban phenomenology" and what it represents in theoretical-methodological terms. So, this article seeks to discuss the use of phenomenology in research on urban spaces through a literature review that covered articles published by Brazilian researchers from the year 2000 onwards. It was observed that the researches are based on the same philosophical bases and that they explore them more regularly. Thus, it is considered that the explanations of methodological procedures for data collection and analysis are infrequent and represent a gap in research with phenomenological approaches, but, above all, an inevitable debate.
O Art-Déco nas estações ferroviárias brasileiras: o estilo moderno e o modal em declínio (1930-1950)
Authors: Ribeiro Eduardo Bacani , Soukef Junior Antônio
Published: April 2024

This article aims to identify the presence of the Art-Deco style in the architecture of Brazilian railway stations, taking as a reference images of buildings of this type that belonged to different railway companies. Such reflection demonstrates, among other issues, that the aforementioned language, at a given moment, presented a certain frequency in different railway companies and thus characterized the features of a typology that, directly, was associated with the machine, a reference for the style Art Deco. By focusing on this theme, the text does not aim to exhaust it. On the contrary, it seeks to open the way for a discussion that has yet to take shape and to elucidate several points that, in this sense, need to be clarified.
Ressignificar a moradia diante da condição cis-heteropatriarcal contemporânea
Authors: Sardá-Vieira Marcos , Flores Maria Bernardete Ramos
Published: April 2024

This article presents some experiences based on different ways of living, beyond the segregating and excluding meaning of cis-heteropatriarchal housing, throughout the 20th century. Based on feminism, we also question spatial regulation, consolidated in the 19th century within the scope of architectural and social transformations linked to the formation of the “housing-case”. Furthermore, we highlight the notion of the hegemonic binary division of technologies of gender and sexualities by having repercussions on material culture, on ways of inhabiting the city and on the diversification of alliances and coexistence, beyond the segregating and excluding meaning of the conventional idea of housing. After all, by making other experiences of living impossible, what are the effects of cis-heteropatriarchal policies associated with the pattern of housing design?
Ler e compreender a cidade: pressupostos para uma análise hermenêutica da herança material do espaço urbano
Authors: Sales Júnior Dário Ribeiro de
Published: April 2024

The purpose of this article is to understand the theoretical assumptions underlying an urban hermeneutics. Here, we will focus on the implications of  understanding the urban infrastructure and the buildings that were bequeathed to us by generations that preceded us in an analogous way to a text.  therefore, we will seek to clarify some basic notions of Paul Ricoeur's hermeneutics. Furthermore, it will be possible to envision the advantages, in terms ofour relationship with the city, of considering the past as a “space of experience” and the future as a “horizon of expectations”, as suggested by Reinhart  Koselleck. I believe that, like written discourse, the material heritage of cities has semantic autonomy and can be interpreted today in multiple ways by its readers. In this way, we can say that the actions that unfold in the historical present see the past as an inexhaustible source of resources and possibilities.
Glypturus ferox, a new species of ghost shrimp (Decapoda: Axiidea: Callichiridae) from the Ryukyu Islands, southwestern Japan
Authors: SATO TAIGI , KOMAI TOMOYUKI , SHIMIZU NAOTO
Published: April 2024

The callichirid ghost shrimp genus Glypturus Stimpson, 1866 was represented until now by four extant species world-wide. Only G. armatus A. Milne-Edwards, 1870 is known from the western Pacific. In this study, we describe G. ferox n. sp. based on seven specimens collected from the Ryukyu Islands, southwestern Japan. All specimens of the new species were collected in inner reef lagoons by suction pump. The new species is easily distinguished from all other congeners, including fossil taxa, by having a row of spines on the lower margin of the major cheliped palm. Molecular phylogenetic analysis using the mitochondrial 16S rRNA gene suggests that G. ferox n. sp. is sister to G. armatus; the genetic divergence between the two species is high. An identification key to extant species of Glypturus is provided. A brief overview on Japanese species of Callichiridae is also provided. Glypturus ferox n. sp. is the nineth species of the family known from Japanese waters with certainty.
Identities revealed: female of Anastrepha cruzi Lima, 1934 and Anastrepha caballeroi Norrbom, 2015 (Diptera, Tephritidae) found in the Brazilian Amazon Rainforest
Authors: URAMOTO KEIKO , ARAÚJO ALEXANDRE S. , SAVARIS MARCOANDRE , COSTA-SILVA FRANCISCO C. , SILVA NELITON M. DA , ZUCCHI ROBERTO A.
Published: April 2024

Anastrepha cruzi was described in 1934, from a specimen without an abdomen. The holotype is the only known record for this species, collected in the Brazilian Amazon Rainforest (location unknown). However, during fruit fly surveys with McPhail-type traps on the campus of the Federal University of Amazonas in Manaus (state of Amazonas), two females were identified as A. cruzi, based on thoracic and wing patterns. These females are described in detail here, including the aculeus tip, to clarify the identity and facilitate recognition of A. cruzi. A single female of A. caballeroi Norrbom was also collected in these surveys, and this species is recorded here for the first time in Brazil.
A Convolutional Neural Network for Tropical Cyclone Wind Structure Identification in Kilometer-Scale Forecasts
Authors: Raynaud L. , Faure G. , Puig M. , Dauvilliers C. , Trosino J.-N. , Béjean P.
Published: April 2024

Detection and tracking of tropical cyclones (TCs) in numerical weather prediction model outputs is essential for many applications, such as forecast guidance and real-time monitoring of events. While this task has been automated in the 1990s with heuristic models, relying on a set of empirical rules and thresholds, the recent success of machine learning methods to detect objects in images opens new perspectives. This paper introduces and evaluates the capacity of a convolutional neural network based on the U-Net architecture to detect the TC wind structure, including maximum wind speed area and hurricane-force wind speed area, in the outputs of the convective-scale AROME model. A dataset of 400 AROME forecasts over the West Indies domain has been entirely hand-labeled by experts, following a rigorous process to reduce heterogeneities. The U-Net performs well on a wide variety of TC intensities and shapes, with an average intersection-over-union metric of around 0.8. Its performances, however, strongly depend on the TC strength, and the detection of weak cyclones is more challenging since their structure is less well defined. The U-Net also significantly outperforms an operational heuristic detection model, with a significant gain for weak TCs, while running much faster. In the last part, the capacity of the U-Net to generalize on slightly different data is demonstrated in the context of a domain change and a resolution increase. In both cases, the pretrained U-Net achieves similar performances as the original dataset.
Program Factors Associated With Improved American Board of Surgery Examination Pass Rates
Authors: Ray Velez David
Published: April 2024

Introduction

The American Board of Surgery awards board certification after successful completion of both the Qualifying Exam and Certifying Exam. Although multiple studies have evaluated board performance at the resident level, fewer studies have evaluated board performance at the program level.

Methods

Program pass rates, available through the American Board of Surgery, for 2019-2021 were compared to program information through the American Medical Association Fellowship and Residency Electronic Interactive Database Access (FREIDA).

Results

A significant positive correlation of Certifying Exam performance to residency length, resident class size, and number of total physician faculty within the program was seen. Greater average hours of didactics per week had a significant positive correlation to improved Qualifying Exam performance but not Certifying Exam. Programs with higher percentages of residents graduating from a United States MD program, compared to international or DO schools, were associated with improved performances. It also appears that more established programs performed better than younger programs <20 years old. Programs in the West and Midwest performed significantly better on the Qualifying Exam than programs in the South and Northeast.

Conclusion

Board certification serves as the capstone for surgeons after completing general surgery residency. Multiple program factors demonstrate a significant correlation to board performance.
Service Sector Growth and Inequality in India: An Analysis of Household Consumption Spending
Authors: Talreja Chaitanya
Published: April 2024

Two important aspects of service sector growth in India in the post-1991 reform period from the demand side have been identified in the literature. Ghose (2015) suggests that the rapid service demand expansion has been driven by the rich, who have disproportionately benefited from the information and communication technology (ICT)-based service boom. Basu and Das (2017) argue that service spending by the poorer section also rose, and the service demand expansion is partly a result of the coercive nature of privatised service expansion. This article examines these two critical aspects in greater detail using the National Sample Survey Organisation (NSSO) consumer expenditure surveys from 1993–94, 2004–05 and 2011–12. The article finds clear evidence to show that the service expenditure in India was dominated by the top 20% of Indian households. Even as bottom 20% devoted larger household budget share to services over time, their share in aggregate service expenditure remained marginal. State per capita income, servicification of output, social expenditure by the government, urbanisation and changing nature of the economy post liberalisation are found to be important factors associated with variation in household service expenditure share across quintile classes. The relationships of these factors with service expenditure share differ across expenditure quintiles. Further, service expenditure elasticity estimates by decile classes indicate more than unit elasticity for various services over time, depicting non-saturating demand for services. The decile-wide rise in demand for services during this period, especially for the poorer households, is possibly due to a complex mechanism involving necessity, aspirations and enhanced access to new services and may not fit into the binary of discretion versus involuntary spending.

JEL Codes: O1, L16, L80, D30, D12
Analysis of load-bearing characteristics of bi-modulus composite stiffened plates: Numerical simulation method and large-scale experimental verification
Authors: Ye Zhenzhou , Li Xiaobin , Lv Lin , Xie Weimeng , Chen Wei , Shen Wei
Published: April 2024

A large number of experiments show that composite materials usually show different modulus properties in tension and compression (bi-modulus). However, for actual composite engineering structures, especially complex models, the numerical simulation calculation is usually based on a single modulus. In order to consider the different modulus characteristics of composite materials in tension and compression, researchers put forward simplified constitutive models of dual-modulus materials. However, these constitutive models have not been verified by a large number of experiments, especially by complex models. In this paper, the GWFMM model is simplified and used to analyze complex structures with different modulus in tension and compression. The experimental results of stiffened plate show that the improved GWFMM model can be used to analyze different modulus of tension and compression of complex stiffened structures. In addition, the influence of elastic modulus ratio in tension and compression under different experimental load conditions is further explored, and the influence law of bending and torsion on structures with bi-modulus is discussed. The relevant conclusions provide reference for the design and optimization of full-scale composite structures in marine engineering.
Family Caregiving of Patients With Heart Failure and Vascular Dementia in Rural Appalachia: A Mixed-Methods Study
Authors: Piamjariyakul Ubolrat , Wang Kesheng , Smith Marilyn , Young Stephanie , Shafique Saima , Navia R. Osvaldo , Williams Kristine
Published: March 2024

Introduction:

Vascular dementia and heart failure (HF) are common co-existing conditions among adult populations. Each condition requires extensive home caregiving from family caregivers, especially those in rural Appalachia. This study aimed to assess caregivers’ burden and their physical and mental health status, as well as explore their experiences and needs.

Methods:

This study used an exploratory mixed-methods design combining quantitative and qualitative research (N = 20 caregivers). We collected data using questionnaires, short-answered interviews, and focus group discussions. The multivariable generalized linear model (GLiM) was used to analyze quantitative data; content analysis was used for qualitative data.

Results:

The average age of family caregivers was 64.95 years. The generalized linear model showed that the caregiving burden was associated with caregivers’ depression/anxiety ( r = 0.68, P < .001) and their number of dementia caregiving years ( r = 0.54, P < .05). Caregivers’ poor physical health status was associated with better preparedness for HF and dementia home caregiving ( r = 0.52, P < .05) and male caregivers ( r = −0.46, P < .01). Caregivers’ mental health status was associated with depression/anxiety ( r = −0.80, P < .001). The qualitative data identified key caregiving themes: emotional impact and physical demands of caregiving, lack of help in rural areas, dealing with multiple disease progression, and relationship changes with their loved ones.

Conclusion:

Caregiving burden was associated with caregivers’ home care responsibilities and the need for support. Nurse-led home caregiving preparedness interventions tailored for family caregivers of patients with HF and dementia in rural areas are recommended.
How do you build the perfect friend? Evidence from two forced-choice decision-making experiments
Authors: Ayers Jessica D. , Krems Jaimie Arona , Aktipis Athena
Published: April 2024

Friendship is a unique and underexplored area of human sociality. Research suggests that humans have preferences for characteristics in their friends that maximize the benefits of these relationships. Yet, whereas more friends might increase friendship benefits, humans also have limited time, resources, and energy to invest in finding high-quality friends, making it likely that the nature of these preferences differs depending on the resources an individual has available to invest in this goal. Across two studies (total N = 693), we investigated how this trade-off may function by investigating the nature of friendship preferences. In Study 1, we utilized the budget paradigm method from behavioral economics to investigate the necessities and luxuries in friendship preferences. In Study 2, we replicated these preferences with a novel method and extended our investigation into understanding the hierarchical nature of these preferences. Taken together, our results provide a promising starting point for research investigating trade-offs between necessities and luxuries in friendship preferences.
The Importance of Medial Patellar Shape as a Risk Factor for Recurrent Patellar Dislocation in Adults
Authors: Sheehan Frances T. , Shah Paras , Boden Barry P.
Published: April 2024

Background:

Research on the cause of lateral patellar dislocation (LPD) has focused on trochlear morphologic parameters, joint alignment, and patellofemoral soft tissue forces. A paucity of information is available regarding how patellar morphologic parameters influence the risk for LPD.

Purpose/Hypothesis:

The purpose was to assess whether patellar morphology is a risk factor for recurrent LPD. It was hypothesized that (1) patients with recurrent LPD would have decreased patellar width and volume and (2) patellar morphologic parameters would accurately discriminate patients with recurrent LPD from controls.

Study Design:

Cohort study (diagnosis); Level of evidence, 3.

Methods:

A total of 21 adults with recurrent LPD (age, 29.7 ± 11.1 years; height, 170.8 ± 9.9 cm; weight, 76.1 ± 17.5 kg; 57% female) were compared with 21 sex- and height-matched controls (age, 27.2 ± 6.7 years; height, 172.0 ± 10.6 cm; weight, 71.1 ± 12.8 kg; 57% female). Three-dimensional axial fat-saturated magnetic resonance imaging scans were used to measure patellar medial, lateral, and total width; patellar volume; patellar medial and lateral facet length; the Wiberg index; and previously validated knee joint alignment and femoral shape measurements (eg, tibial tuberosity to trochlear groove distance, trochlear dysplasia).

Results:

The LPD group demonstrated reduced medial patellar width (Δ = −3.6 mm; P < .001) and medial facet length (Δ = −3.7 mm; P < .001) but no change in lateral width or facet length. This resulted in decreased total patellar width (Δ = −3.2 mm; P = .009), decreased patellar volume (Δ = −0.3 cm3; P = .025), and an increased Wiberg index (Δ = 0.05; P < .001). No significant differences were found for all other patellar shape measures between cohorts. Medial patellar width was the strongest single discriminator (83.3% accuracy) for recurrent LPD. Combining medial patellar width, patellofemoral tilt, and trochlear groove length increased the discrimination to 92.9%.

Conclusion:

The medial patellar width was significantly smaller in patients with recurrent LPD and was the single most accurate discriminator for recurrent LPD, even compared with traditional trochlear shape and joint alignment measures (eg, trochlear dysplasia, patella alta). Therefore, medial patellar morphology should be assessed in patients with LPD as a risk factor for recurrence and a potential means to improve treatment.
Torsional strength design method and cost analysis of FRP bars reinforced ECC beams without stirrups
Authors: Liao Qiao , Su Yuan-Rui , Yu Ke-Quan
Published: April 2024

Fiber reinforced plastic (FRP) bars reinforced engineered cementitious composites (ECC) beams without stirrups own excellent torsional performance and good application prospect. However, the corresponding torsional strength design method is not available. In order to predict the torsional strength of the ECC beams, a theoretical design method is established in this research. The proposed design method is based on the variable-angle space truss (VAST) model, and the tensile resistance supplied by fibers is carefully considered. The established design method is verified through the experimental results. It can be found that the predicted values agree well with the experimental values. A parametric analysis is carried out. Ultimate torque (i.e., torsional strength) increases significantly with the increment of ECC strength grade or longitudinal reinforcement ratio. However, at the same cross-section area, ultimate torque decreases slightly with the increment of height/width ratio. In addition, the cost effectiveness of the ECC beams without stirrups is discussed. Compared with mortar beam with a stirrup reinforcement ratio of 0.7%, FRP bars reinforced ECC beams without stirrups have small cost/ultimate torque ratio (a reduction ratio of 39.14%–60.86%), indicating that the ECC beams without stirrups own satisfactory cost effectiveness. This study will provide a torsional strength design guideline for FRP bars reinforced ECC beams without stirrups.
Perceived Ageism is Associated With Recurrent Falling Among Older Colombian Adults
Authors: Reyes-Ortiz Carlos A. , Robinson Crystall C. , Williams Donna R. , Moncayo-Hernández Brigitte A. , Ocampo-Chaparro Jose M. , Cheung Nicole , Campo-Arias Adalberto
Published: April 2024

Literature on the association between ageism and falling among older adults is limited. Using data from the nationwide cross-sectional SABE ( Salud, Bienestar y Envejecimiento) Colombia Survey in 2015 with 18,875 participants aged ≥60 years living in the communities, the study aims to evaluate the association between perceived ageism within the family, neighborhood, health services, and public services, and recurrent falling. Participants had a mean age of 69.2 ± 7.1; 56.1% were female. Recurrent falling prevalence was 15%, and experiencing any ageism was 10%. Multivariable logistic regression analyses showed higher odds of recurrent falling for any ageism (OR = 1.81, 95% CI 1.61–2.02, p < .0001). High depressive symptoms mediated 10.1% of the association between any ageism and recurrent falling, followed by low instrumental activities of daily living (9.7%) and multimorbidity (9.3%). Current findings open new areas of gerontological research by expanding the risk factors for falling among older adults to include ageism perceptions.