bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamics of Photoinduced Charge Carriers in Metal-Halide Perovskites
Authors: Bojtor András , Krisztián Dávid , Korsós Ferenc , Kollarics Sándor , Paráda Gábor , Kollár Márton , Horváth Endre , Mettan Xavier , Márkus Bence G. , Forró László , Simon Ferenc
Published: October 2024

The measurement and description of the charge-carrier lifetime (τc) is crucial for the wide-ranging applications of lead-halide perovskites. We present time-resolved microwave-detected photoconductivity decay (TRMCD) measurements and a detailed analysis of the possible recombination mechanisms including trap-assisted, radiative, and Auger recombination. We prove that performing injection-dependent measurement is crucial in identifying the recombination mechanism. We present temperature and injection level dependent measurements in CsPbBr3, which is the most common inorganic lead-halide perovskite. In this material, we observe the dominance of charge-carrier trapping, which results in ultra-long charge-carrier lifetimes. Although charge trapping can limit the effectiveness of materials in photovoltaic applications, it also offers significant advantages for various alternative uses, including delayed and persistent photodetection, charge-trap memory, afterglow light-emitting diodes, quantum information storage, and photocatalytic activity.
Cyproheptadine Treatment in Children and Adolescents with Migraine: A Retrospective Study in Japan
Authors: Shimomura Hideki , Tokunaga Sachi , Terasaki Eisuke , Taniguchi Naoko , Taniguchi Yohei , Yoshitake Saeka , Terakita Yuki , Inoue Kenji , Okuda Masumi , Kato Takeo , Takeshima Yasuhiro
Published: October 2024

Objective: Evidence on prophylactic drugs for pediatric migraine is limited, especially when comorbid conditions contribute to treatment resistance. This study evaluated the efficacy of cyproheptadine in children with migraine and explored the impact of comorbid neurodevelopmental disorders and orthostatic intolerance (OI). Methods: We retrospectively analyzed pediatric migraine patients treated with cyproheptadine. Efficacy was assessed based on the reduction in headache frequency, with responders defined as patients experiencing at least a 50% reduction in headache episodes. Fisher’s exact test analyzed the relationship between efficacy and comorbid conditions or treatment sequence. Multiple logistic regression was performed to identify factors associated with adverse events. Results: In total, 155 children (71 males, 84 females) aged 3–15 years were included. Comorbid neurodevelopmental disorders and OI were present in 27 (17.4%) and 22 (14.2%) patients, respectively. Efficacy was evaluated in 148 patients, with 68.9% classified as responders. Patients with comorbid conditions showed lower efficacy. Responders required a lower dose of cyproheptadine (p = 0.039). Multiple logistic regression identified headache frequency, cyproheptadine dose, and comorbid OI and neurodevelopmental disorders as factors influencing treatment efficacy. Conclusions: Cyproheptadine is effective in treating pediatric migraine, though patients with neurodevelopmental disorders and OI demonstrated reduced efficacy.
Towards Understanding the Motivators of Sustainable Consumer Behavior—Validation of the Food Eco-Guilt Scale
Authors: Unger-Plasek Brigitta , Temesi Ágoston , Lakner Zoltán
Published: October 2024

Background/Objectives: The growing concern about the environmental impacts of consumption has led to the emergence of so-called “eco-guilt”—a psychological construct reflecting the guilt felt by individuals about the environmental consequences of their choices, which plays a prominent role among the factors influencing pro-environmental behavior. Although eco-guilt has already emerged in other service sectors, such as tourism, and general scales exist to measure it, no such scale exists in the context of food consumption. The aim of this research is to develop and validate a scale to measure eco-guilt related to food consumption. Methods: To create the scale in an objective way, we used the Sustainable Development Goals as a framework. Data were collected from university students; a questionnaire was completed online by 367 respondents. The responses were analyzed from several different perspectives, using multiple methods following the principle of triangulation. For the data analysis, the Psych and Mokken packages of R software (version 4.4.0) were used. Results: The constructed scale was based on 13 items. An overview of the reliability of the scale was provided using various indicators (e.g., Cronbach’s α = 0.86, ωh = 0.63, ωH asymptotic = 0.71, and ωt = 0.89). Based on the analyses, we proposed a reduced form with nine items for the measurement of food-related eco-guilt. Conclusions: The results of this research provide a scale to help understand what motivates consumers to make more sustainable consumption choices. Moreover, the scale is relevant to future research focused on understanding how guilt influences future food choices.
Dietary Intake Is Similar Among Adult Men with Different Levels of Cold-Induced Brown Adipose Tissue Activation
Authors: Carrillo Andres E. , Dinas Petros C. , Krase Argyro , Nintou Eleni , Georgakopoulos Alexandros , Metaxas Marinos , Ryan Edward J. , Vliora Maria , Georgoulias Panagiotis , Chatziioannou Sofia , Flouris Andreas D.
Published: October 2024

Background/Objectives: Brown adipose tissue (BAT) activation has important metabolic health implications, yet the relationship between habitual dietary intake and BAT activity in humans remains to be fully understood. Methods: We compared dietary intake among adult men with (BATpositive, age: 34.8 ± 5.4 years, BMI: 28.2 ± 5.3 kg/m2, n = 12) and without (BATnegative, age: 39.1 ± 4.1 years, BMI: 31.1 ± 6.7 kg/m2, n = 11) cold-induced BAT activation. Activation of BAT was measured immediately following 2 h of cold exposure using 18F fluorodeoxyglucose positron emission tomography and computed tomography reported as maximum standardized uptake (SUVmax). Participants categorized as BATpositive had an SUVmax > 1.5 g/mL that was normalized to lean body mass (SUVlean) for analysis. Shivering intensity was recorded every 15 min during cold exposure and dietary intake was estimated from 7 consecutive 24 h dietary recalls. Results: The BATnegative group was significantly older than the BATpositive group (p = 0.046). Although BATnegative participants consumed an average of 281.2 kcal/day more than BATpositive, there were no significant differences in dietary intake between groups (p ≥ 0.202). Further, no statistically significant associations between SUVlean and dietary intake among BATpositive participants were observed (p ≥ 0.175). Participants who shivered (n = 9) during cold exposure tended to be shorter (p = 0.056) and have a lower waist-to-hip ratio (p = 0.097) but did not differ in dietary intake (p ≥ 0.204) or BAT activity (p = 0.964) when compared to the non-shivering (n = 11) group. Conclusions: Our results indicate that BAT activity and shivering during cold exposure are more strongly related to variables such as age and body size or composition rather than habitual dietary intake. We conclude that habitual dietary intake likely has a negligible influence on BAT activity among adult men.
Body Weight and Food/Eating-Related Behaviors During the COVID-19 Pandemic or Other Traumatic or Stressful Life Events
Authors: Argyrides Marios , Dakanalis Antonios
Published: October 2024

The COVID-19 pandemic has been a pivotal event, reshaping many aspects of daily life and public health across the globe [...]
QSAR Regression Models for Predicting HMG-CoA Reductase Inhibition
Authors: Ancuceanu Robert , Popovici Patriciu Constantin , Drăgănescu Doina , Busnatu Ștefan , Lascu Beatrice Elena , Dinu Mihaela
Published: October 2024

Background/Objectives: HMG-CoA reductase is an enzyme that regulates the initial stage of cholesterol synthesis, and its inhibitors are widely used in the treatment of cardiovascular diseases. Methods: We have created a set of quantitative structure-activity relationship (QSAR) models for human HMG-CoA reductase inhibitors using nested cross-validation as the primary validation method. To develop the QSAR models, we employed various machine learning regression algorithms, feature selection methods, and fingerprints or descriptor datasets. Results: We built and evaluated a total of 300 models, selecting 21 that demonstrated good performance (coefficient of determination, R2 ≥ 0.70 or concordance correlation coefficient, CCC ≥ 0.85). Six of these top-performing models met both performance criteria and were used to construct five ensemble models. We identified the descriptors most important in explaining HMG-CoA inhibition for each of the six best-performing models. We used the top models to search through over 220,000 chemical compounds from a large database (ZINC 15) for potential new inhibitors. Only a small fraction (237 out of approximately 220,000 compounds) had reliable predictions with mean pIC50 values ≥ 8 (IC50 values ≤ 10 nM). Our svm-based ensemble model predicted IC50 values < 10 nM for roughly 0.08% of the screened compounds. We have also illustrated the potential applications of these QSAR models in understanding the cholesterol-lowering activities of herbal extracts, such as those reported for an extract prepared from the Iris × germanica rhizome. Conclusions: Our QSAR models can accurately predict human HMG-CoA reductase inhibitors, having the potential to accelerate the discovery of novel cholesterol-lowering agents and may also be applied to understand the mechanisms underlying the reported cholesterol-lowering activities of herbal extracts.
Afro-Latin American Pharmacogenetics of CYP2D6, CYP2C9, and CYP2C19 in Dominicans: A Study from the RIBEF-CEIBA Consortium
Authors: Guevara Mariela , Rodrigues-Soares Fernanda , de la Cruz Carla González , de Andrés Fernando , Rodríguez Ernesto , Peñas-Lledó Eva , LLerena Adrián ,   CEIBA Consortium of the Ibero-American Network of Pharmacogenetics and Pharmacogenomics RIBEF
Published: October 2024

Background/Objectives: Research on pharmacogenetic variability in response to prescribed drugs and across ethnic groups is essential for personalized medicine, particularly in admixed and unstudied populations. For the first time, this study examines CYP2D6, CYP2C9, and CYP2C19 alleles and genotypes in 197 healthy volunteers from the Dominican Republic, as part of the RIBEF-CEIBA collaborative network. Methods: The analysis focuses on the participants’ tri-hybrid genomic ancestry, with CYP alleles determined by real-time PCR and molecular ancestry inferred using 90 AIMs. Linear regression was used to associate ancestry components with CYP frequencies. Results: The average ancestry was 23.8% European, 42.6% Native American, and 33.6% African, the latter being higher than in most Latin American populations. Native American ancestry was also higher than expected. Predicted phenotype frequencies based on genotypes were 4.2% poor metabolizers (gPMs) and 3.6% ultrarapid metabolizers (gUMs) for CYP2D6, as well as 3% gPMs, 22.8% rapid metabolizers (gRMs), and 1.5% gUMs for CYP2C19. No gPM individuals were observed for CYP2C9. Certain alleles associated with decreased CYP2D6 activity (*17 and *29) and increased CYP2C19 activity (*17 and gUMs) were positively linked with African ancestry and negatively with Native American ancestry. Rare CYP2C9 alleles (*5 and *6) with clinical relevance were additionally found. Conclusions: These findings build on previous results from the RIBEF-CEIBA collaborative network, demonstrating differences in allele frequencies of CYP2D6, CYP2C9, and CYP2C19 in relation to genomic ancestry. In summary, ethnicity must be considered in the development of pharmacogenetic guidelines for clinical application, research, and regulation to avoid widening the biotechnology gap and to allow Personalized Medicine to reach the entire world population.
Photonic-Metamaterial-Based, Near-Field-Enhanced Biosensing Approach for Early Detection of Lung and Ovarian Cancer
Authors: Geng Shuo , Zhang Xuguang , Liang Haiyan , Zheng Yi
Published: October 2024

Early detection of lung and ovarian cancers relies heavily on identifying tumor biomarkers, but current methods require large blood samples and complex genetic testing. This study presents a novel photonic-metamaterial-based biosensing approach that leverages near-field radiative enhancement to detect cancer biomarkers (CA 125, CEA, and CYFRA 21-1) with high sensitivity. By utilizing structured photonic metamaterials, we optimize specific wavelengths to identify these biomarkers in interstitial fluid, which can be easily collected via minimally invasive microneedle arrays. Integrating near-field interactions with wavelength-selective metamaterials amplifies the thermal response at the nanoscale, allowing for the detection of deficient concentrations of biomarkers. This photonic metamaterial technique provides a faster, more accessible, and affordable alternative to conventional blood-based methods, significantly improving early detection and monitoring of cancer. Ultimately, this approach offers a transformative tool for clinical and research applications in cancer diagnostics.
Correction: Mani et al. Bioassay Guided Fractionation Protocol for Determining Novel Active Compounds in Selected Australian Flora. Plants 2022, 11, 2886
Authors: Mani Janice , Johnson Joel , Hosking Holly , Hoyos Beatriz E. , Walsh Kerry B. , Neilsen Paul , Naiker Mani
Published: October 2024

In the original publication [...]
Crystallization-Controlled Structure and Thermal Properties of Biobased Poly(Ethylene2,5-Furandicarboxylate)
Authors: Pluta Miroslaw , Bojda Joanna , Svyntkivska Mariia , Makowski Tomasz , de Boer Ele L. , Piorkowska Ewa
Published: October 2024

Crystallization-controlled structure and thermal properties of biobased poly(ethylene 2,5-furandicarboxylate) (PEF) were studied. The cold-crystallization temperature controlled the structure and thermal properties of the biobased PEF. The melting was complex and evidenced the presence of a significant fraction of less-stable crystals with a low melting temperature that linearly increased with Tc, which formed already during the early stages of crystallization, together with those melting at a higher temperature. Low Tc resulted in the α’-phase formation, less crystallinity, and greater content of the rigid amorphous phase. At high Tc, the α-phase formed, higher crystallinity developed, the rigid amorphous phase content was lower, and the melting temperature of the less-stable crystals was higher; however, slight polymer degradation could have occurred. The applied thermal treatment altered the thermal behavior of PEF by shifting the melting of the less stable crystals to a significantly higher temperature. SEM examination revealed a spherulitic morphology. A lamellar order was evidenced with an average long period and small average lamella thickness, the latter about 3–3.5 nm, only slightly increasing with Tc.
Lay Religious Associations in Extractive Zones: A Case Study of Diamantina, Brazil
Authors: Janzen Rebecca
Published: October 2024

This article considers religion in extractive zones by focusing on a religious practice in an extractive zone, namely, an Afro-Brazilian Irmandade (Catholic lay religious association) devoted to Our Lady of Mercy in Diamantina, Minas Gerais, Brazil. It adopts approaches from history and cultural studies to examine art, architecture, archives, and material culture, and brings these methodologies into conversation with Mary Louis Pratt’s notion of contact zones, Charles Long’s connection between these zones and new religious practices, Eduardo Gudynas’ definition of extraction, and Macarena Gómez-Barris’ decolonial methodologies for approaching the study of extractive zones. This study is contextualized in the history of mining in Brazil, the connection between mining and enslavement of Africans in the Americas, and the enduring legacy of lay religious associations in Brazil. The article then examines the association’s church, focusing on its late 18th and early 19th century façade and the statues at its main altar, and its 19th and 20th century maintenance records. It suggests that the Irmandades are engaged in a unique religious practice that arises within an extractive region because of specific historical, political, and social reasons, and that they give their members a place within the existing structures even as they challenge them.
A Reading of 2 Kings 18:17–19:9a, 36–37 as a Trauma Narrative
Authors: Lee Woo Min
Published: October 2024

The narrative of 2 Kings 18:17–19:9a, 36–37 (“Source B1”) recounts pre-exilic religious collective trauma surrounding Sennacherib’s military advance against Judah in 710 BCE and its aftermath. In this narrative, the Rabshakeh uses the keywords “בטח” and “נצל” to assert that Yhwh has turned against Judah. However, his claims were subverted by the withdrawal of the Assyrian army and the later death of Sennacherib, facilitated by the divine intervention of Yhwh following Hezekiah’s supplication. Despite its significance, only a few studies have examined this narrative as that of trauma. Drawing on Jeffrey Alexander’s theory of the social process of cultural or collective trauma, this study argues that the function of this narrative is that of religious trauma narrative. It reconstructs the collective trauma of Sennacherib’s campaign to theologically defend the Davidic kingship and Yhwh and ultimately suggests a revised identity for the Judaean community to foster solidarity, even under the ongoing influence of Assyria following the military campaign.
Revising the Original Antonovsky Sense of Coherence Concepts: A Mixed Method Development of the Sense of Meaning Inventory (SOMI)
Authors: Saint Arnault Denise M. , Zonp Zeynep
Published: October 2024

Trauma recovery research requires the development of instruments that capture gender-based violence (GBV) survivor recovery phases. The salutogenic concepts in Antonovsky’s Sense of Coherence (SOC) (manageability, comprehensibility, and meaning) could help capture trauma recovery stages, but the factorial structure of the SOC-13 has remained problematic. Moreover, most SOC revisions generally abandon the original intent of the SOC-13, developing scales that capture essential but different aspects of positive psychology. This study used mixed methods to develop the Sense of Meaning Inventory (SOMI), preserving the original concepts but updating the language, removing cultural idioms, and revising the response scales to stabilize the subscales. The qualitative phase evaluated and updated the items of the scale while retaining the original concepts. The quantitative phase conducted a two-sample psychometrics reliability and validity evaluation of the new scale with GBV survivors, finding a three-factor solution. This scale may be more amenable for international research and theory testing in GBV and other health conditions.
Environmental Sustainability Assessment of Tissue Paper Production
Authors: Dias Ana C. , Carvalho Ricardo , Marques Cristina , Bértolo Raquel , Carta Ana , Machado Luís
Published: October 2024

The environmental performance of tissue paper varies greatly based on factors such as the type of fibre used as the raw material, the production process and the fuels used to meet the energy requirements. One possible strategy to decrease greenhouse gas emissions in tissue production is the integration of pulp and paper mills and their energy systems at the same site. However, the environmental trade-offs associated with this strategy are still unclear. Therefore, this study aimed (i) to assess for the first time the environmental impacts of tissue paper produced at a typical industrial site in Portugal using slush and market pulp as the main raw material, and (ii) to assess the environmental effects of the integration of bioenergy produced in the pulp mill in tissue production. A life cycle assessment was conducted from cradle to gate using real data from the production of eucalyptus wood, eucalyptus pulp and tissue paper. The results showed that energy consumption in tissue paper production is the main hotspot for most impact categories. When bioenergy is used in tissue production, the environmental impacts decrease by up to 20% for categories other than marine eutrophication and mineral resource scarcity. These results are relevant to support decision making concerning sustainable practices not only for the pulp and paper industry but also for the authorities in charge of defining environmental policies, incentives and tax regulations.
Traditional African Vegetables Knowledge Translation: A Scoping Review
Authors: Mdimi Meab Clara , Dent Benjamin , Reid Simon , Makindara Jeremia , Thomas Preetha
Published: October 2024

Traditional African vegetables (TAVs) are an important component of an ecologically sustainable approach to addressing food and nutrition security in Africa. This review aims to identify the scope of the knowledge translation literature that exists across multiple aspects of the TAV value chain and to identify gaps in knowledge translation research. A scoping review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) was conducted. The Population, Concept, and Context (PCC) framework was used to guide the development of inclusion and exclusion criteria for this review. The Web of Science, Scopus, Science Direct, and ABI/Inform databases were searched to identify the relevant studies which were then screened using the Covidence 2024 online software to select studies and extract information for analysis and reporting. A total of 182 studies/articles were selected and examined. The most significant knowledge documented about TAVs pertains to their vast genetic diversity contributing to their rich nutritional and medicinal properties, their ability to withstand harsh environmental conditions such as drought, pests, and diseases, as well as the effects of various post-handling techniques on the nutrient content of TAVs, with the production phase of the TAV value chain being the most studied. This review found that, although a breadth of knowledge about TAVs has been generated, there is still little documentation about transferring and utilizing this knowledge across the TAV value chain. This review identified that more research is needed to document the strategies and practices for the transfer and utilization of knowledge to ensure that it is utilized to enhance nutritional outcomes across Africa.
The Influence of Gas Fuel Enrichment with Hydrogen on the Combustion Characteristics of Combustors: A Review
Authors: Ghazal Rabeea M. , Akroot Abdulrazzak , Abdul Wahhab Hasanain A. , Alhamd Abdulrahman E. J. , Hamzah Ameer Hasan , Bdaiwi Mothana
Published: October 2024

Hydrogen is a promising fuel because it has good capabilities to operate gas turbines. Due to its ignition speed, which exceeds the ignition of traditional fuel, it achieves a higher thermal efficiency while the resulting emissions are low. So, it was used as a clean and sustainable energy source. This paper reviews the most important research that was concerned with studying the characteristics of hydrogen combustion within incinerators and power generation equipment, where hydrogen was used as a fuel mixed with traditional fuel in the combustion chambers of gas turbines. It also includes an evaluation of the combustion processes and flame formation resulting from the enrichment of gaseous fuels with hydrogen and partial oxidation. A large amount of theoretical and experimental work in this field has been reviewed. This review summarizes the predictive and experimental results of various research interests in the field of hydrogen combustion and also production.
Impacts of Bedrocks on Vegetation Carbons in Typical Karst Areas: A Case Study in Puding County, Southwest China
Authors: Cai Xianli , Luo Weijun , Liu Changcheng , Chen Jia , Zhang Lin , Cheng Anyun , He Zhongquan , Wang Shijie
Published: October 2024

An accurate estimation of vegetation carbon pools and their carbon sequestration potential is significant in global carbon cycle research but the existing estimations are still insufficient and largely uncertain. Here, we estimated the vegetation carbon density, carbon stocks, and carbon sequestration potential under three main bedrock types (limestone, dolomite, and non-carbonate) in Puding County, Guizhou Province, Southwestern China. The data used here included high-resolution vegetation maps of Puding, data from 274 sample plots, and the carbon contents measured previously in adjacent areas. The land area ratio of natural vegetation at an early stage (namely, grassland and shrub, excluding artificial forests and cultivated land) in carbonate rock areas is significantly larger than that in non-carbonate areas. The average existing carbon densities of vegetation in the non-carbonate, limestone, and dolomite areas were 31.59 ± 7.43, 16.75 ± 4.12, and 8.26 ± 2.45 Mg·ha−1, respectively, while their existing carbon stocks were 752.37 ± 172.85, 855.69 ± 210.65, and 208.49 ± 61.82 Gg, respectively. The maximum vegetation carbon densities of mature forests in the three bedrock types were 156.49 ± 12.92, 130.27 ± 6.05, and 117.41 ± 30.03 Mg·ha−1, respectively. Then, their average vegetation carbon sequestration potentials were 56.07 ± 23.06, 70.13 ± 11.39, and 59.11 ± 33.00 Mg·ha−1, respectively. In other words, vegetation carbon stocks in the non-carbonate, limestone, and dolomite areas increased by 1.34 ± 0.42, 3.58 ± 0.48, and 1.49 ± 0.51 Tg, respectively, after continuous evolution to mature forests. In conclusion, the potential growth of carbon density for karst vegetation is slightly higher than that of non-karst vegetation, despite its lower existing carbon density. Additionally, natural vegetation has a greater potential for carbon sequestration than plantations on all three bedrock types.
Strategic Formation of Agricultural Market Clusters in Ukraine: Emerging as a Global Player
Authors: Sitnicki Maksym W. , Kurinskyi Dmytro , Pimenowa Olena , Wasilewski Mirosław , Wasilewska Natalia
Published: October 2024

This study investigates the cluster approach to optimize strategies for agricultural enterprises in Ukraine, emphasizing geographical proximity as a key factor in cluster formation. The research applies Kohonen Self-Organizing Maps (SOMs) and Ward’s hierarchical clustering to classify enterprises based on storage capabilities, transport logistics, crop yields, and military risk exposure. By analyzing these factors, this study identifies distinct patterns of innovation adoption, strategic management, and economic resilience among the clusters. The findings highlight variations in competitiveness and resource efficiency, providing a detailed understanding of regional economic performance. Unlike previous research, this study offers a novel integration of conflict-related risks into the clustering methodology, revealing new insights into how military factors influence cluster dynamics. Comprehensive maps and diagrams illustrate the spatial and economic distribution of clusters, aiding in visual interpretation. The results propose strategic measures tailored to enhance agricultural productivity and competitiveness, particularly in Ukraine’s current military context. This approach offers a more adaptive framework for managing agricultural enterprises, promoting resilience and long-term sustainability in global markets.
Emerging Threats of Highly Pathogenic Avian Influenza A (H5N1) in US Dairy Cattle: Understanding Cross-Species Transmission Dynamics in Mammalian Hosts
Authors: Sreenivasan Chithra C. , Li Feng , Wang Dan
Published: October 2024

The rapid geographic spread of the highly pathogenic avian influenza (HPAI) A(H5N1) virus in poultry, wild birds, and other mammalian hosts, including humans, raises significant health concerns globally. The recent emergence of HPAI A(H5N1) in agricultural animals such as cattle and goats indicates the ability of the virus to breach unconventional host interfaces, further expanding the host range. Among the four influenza types—A, B, C, and D, cattle are most susceptible to influenza D infection and serve as a reservoir for this seven-segmented influenza virus. It is generally thought that bovines are not hosts for other types of influenza viruses, including type A. However, this long-standing viewpoint has been challenged by the recent outbreaks of HPAI A(H5N1) in dairy cows in the United States. To date, HPAI A(H5N1) has spread into fourteen states, affecting 299 dairy herds and causing clinical symptoms such as reduced appetite, fever, and a sudden drop in milk production. Infected cows can also transmit the disease through raw milk. This review article describes the current epidemiological landscape of HPAI A(H5N1) in US dairy cows and its interspecies transmission events in other mammalian hosts reported across the globe. The review also discusses the viral determinants of tropism, host range, adaptative mutations of HPAI A(H5N1) in various mammalian hosts with natural and experimental infections, and vaccination strategies. Finally, it summarizes some immediate questions that need to be addressed for a better understanding of the infection biology, transmission, and immune response of HPAI A(H5N1) in bovines.
Active Disturbance Rejection Control for Flux Weakening in Interior Permanent Magnet Synchronous Motor Based on Full Speed Range
Authors: Chen Yong , Yuan Ruodan
Published: October 2024

To address the impact of load disturbances on the full-speed-range control of an interior permanent magnet synchronous motor (PMSM), an active disturbance rejection control (ADRC) method is proposed. The speed loop employs phased field-weakening control (FW) based on ADRC, while the current loop utilizes proportional-integral-derivative (PID) control. Starting from the motor parameters, the Lagrange multiplier method was used to derive the critical speeds for the maximum torque per ampere (MTPA) and maximum torque per voltage (MTPV) ratios, and the timing for the field-weakening control was analyzed. A full-speed-range control model of the motor was established, and an ADRC-based speed loop controller was designed to achieve smooth transitions between high speeds and anti-disturbance solid capabilities. Based on the proposed control strategy, a 21 kW PMSM was used as the research object, and a full-speed-range control simulation model was developed in MATLAB/SIMULINK to verify the strategy. Compared to the traditional PID control, the simulation results demonstrate that the proposed strategy effectively observes and compensates for load disturbances, significantly reducing initial torque oscillations under three different operating conditions. After a sudden load increase, torque oscillations were reduced by 16%, with the stator current reaching steady state 0.03 s faster, response speed improving by 0.02 s, smooth transitions between speed ranges, and enhanced anti-disturbance performance.
Realization and most often occupied positions and professions of graduates of communication and computer engineering and informatics and computer science professional fields
Authors: Stefanova Tereza
Published: October 2024

The specialists working in the ICT sector have mostly graduated from the professional fields of Communication and Computer Engineering and Informatics and Computer Science. Students from these two professional fields are educated in a total of 33 higher schools: 17 in Communication and Computer Engineering and 16 in Informatics and Computer Sciences. The article presents information on higher education institutions in both professional fields according to the "Taxable income of graduates" indicator. Data from the Rating System of Higher Education Institutions in Bulgaria in 2022 were used. The most often held positions and professions by graduates of the professional fields of Communication and Computer Engineering and Informatics and Computer Science are shown. Conclusions have been made about the changes in the incomes of the graduates of the two professional fields.
Qualidade dos registros da tuberculose no sistema de informação de notificação: perspectivas de apoiadores e digitadores distritais
Authors: Mejia Casco Evelyn Ninoska , Silva Denise Maria Guerreiro Vieira da , Ramos Flávia Regina Souza , Santos Edinilza Ribeiro dos , Crispim Maria Clara Silva e , Sicsú Amélia Nunes
Published: October 2024

Apesar dos múltiplos esforços realizados em todo o mundo, a tuberculose (TB) continua sendo um problema de saúde pública e um grande desafio para os países com uma carga maior da doença. O sistema de vigilância epidemiológica (VE) da TB tem papel primordial nas atividades de prevenção e controle dessa doença. Este estudo tem como objetivo conhecer a perspectiva de apoiadores técnicos e digitadores sobre o registro de dados no SINAN acerca da tuberculose de uma capital do Norte do país. Estudo qualitativo, exploratório, realizado com oito apoiadores técnicos e digitadores. Os dados foram coletados por entrevista semiestruturada no período de janeiro a junho de 2022 e submetidos à análise temática. Expressos em duas categorias: Compromisso com a qualidade dos dados e Desafios no preenchimento e busca das informações. As principais limitações dos registros de dados estão relacionadas à qualidade dos dados enviados pelas unidades básicas de saúde e à falta de articulação entre os sistemas de registro. Há fragilidades em vários pontos do sistema, apontando a necessidade de investimento para a integração dos sistemas de registro, sensibilização dos profissionais sobre preenchimento adequado das informações; e elaboração de estratégias informatizadas que otimizem o processo de registro.
Miaodao and Miaozong : Women Zen Masters, the Dharma Heirs of Dahui Zonggao in the Song Dynasty
Authors:   Korean Institute for uddhist Studies, Cho Seung Mee
Published: October 2024

Among the official disciples of the Southern Song Dynasty Zen master Dahui Zonggao(1089-1163) of the Chinese Linzi School were two bhikkhunis, Miaodao and Miaozong. Before Miaodao and Miaozong, the only other bhikkhuni in the history of Chinese Zen Buddhism was Moshan Liaoran in Ching-te ch'uan-teng lu. In the Southern Song period, the number of bhikkhunis and lay people recorded in Zen Buddhist texts gradually increased. Writers of Zen Buddhist texts sought to broaden the scope of Zen Buddhism by including royal women and elite men, often criticising the traditional focus on male ascetics. Miaodao and Miaozong were two of the earliest pioneers of this transformation of Zen Buddhism in the Southern Song Dynasty and were highly respected and representative bhikkhuni Zen masters.
This paper examines these two bhikkhunis, Miaodao and Miaozong, through the literature on the history of Zen Buddhism in the Southern Song Dynasty and the writings of Dahui. In order to examine the evaluation of these bhikkhunis and their characteristics in relation to the context of the Southern Song period, the scope of this study is limited to the Zen Buddhist literature of the Southern Song period.
The reason why Zen Buddhist texts record the biographies of many female Zen masters and actively include them in Zen Buddhist genealogies is that the examples of excellent female Zen masters can demonstrate the effectiveness of Zen Buddhist practice and increase the popularity of Zen Buddhism.
Dahui often referred to the examples of Miaodao and Miaozong to teach and inspire his followers, especially women, to practice his Zen meditation. While presenting them as serious practitioners on the path to enlightenment, he also sought to present them as exemplary female leaders for other female students. This shows that he recognised the need for the active participation of women in the spread of his Zen Buddhist practice and in the development of Zen Buddhism.
The Southern Song Dynasty Zen texts that record the Miaodao and Miaozong show an unprecedented high regard for female Zen masters. However, we can also see the limits of the male-centred authoritarianism that still persists in these texts. In the Southern Song Dynasty of China, elites were actively engaged in Zen Buddhism, the bhikkhuni order was highly prominent, and the traditional bhikkhu-centred hierarchy of the transmission records was being challenged. These changes were reflected in the high esteem in which female Zen masters were held.
Management of Seungjeong and Gongeui in the late Goryeo Dynasty
Authors:   Korean Institute for uddhist Studies, Choi Soon Woo
Published: October 2024

This study investigates the transformation of Buddhist administration (Seungjeong) during late Goryeo, reevaluating the role of public opinion (Gong-ui) and the chief inspectors (Dochongseop). Gong-ui was crucial in monk appointments, similar to bureaucratic personnel registers. As Seungjeong became corrupt during the Yuan interference, King Chungseon established Dochongseop positions to ensure fair Gong-ui. The system expanded under King Chungsuk with the Chamhoe-bu but later transitioned to Dochongseops within Seungnoksa. Under King Gongmin, changes included granting monk Bou authority over abbots' appointments. During Shin Don's rule, Seongyodochongseop unified Gong-ui review across sects. This study highlights that the transformation of Buddhist administration in late Goryeo should be viewed in terms of both dysfunctional operations and reformative aspects.
ОБЗОР ПРИМЕНЕНИЯ МЕТОДОВ ВАКУУМНОЙ ТЕРАПИИ В ВЕДЕНИИ ПАЦИЕНТОВ С СОСУДИСТЫМИ ЗАБОЛЕВАНИЯМИ НИЖНИХ КОНЕЧНОСТЕЙ
Authors: М.Ж. Еспенбетова , Н.С. Изатуллаева , Н.Е. Глушкова , Ж.К. Заманбекова , А.Д. Аманова , Л.А. Аббасова , Д.Е. Жангирова , А.М. Досбаева
Published: October 2024

В статье представлены результаты систематического литературного поиска публикаций и других доступных источников отражающие эффективность применения методов вакуумной терапии в ведении пациентов с сосудистыми заболеваниями нижних конечностей. Основная масса публикаций была проиндексирована в базах данных PubMed, MEDLINE, CINAHL, Embase, e-library, Google Scholar. Глубина поиска составила более 30 лет.

The article presents the results of a systematic literature search of publications and other available sources of the efficacy of the methods of vacuum therapy in the management of patients with vascular disease of the lower extremities. The majority of publications was indexed in the databases PubMed, MEDLINE, CINAHL, Embase, e-library, Google Scholar. Search depth was more than 30 years.

Мақалада аяқ тамырларының аурулары кезінде науқастарға ваккумды терапия әдісін қолданудағы әсерінің басқада әдебиеттерде көрсетілген және жүйелік әдебиеттерге ізденіс кезіндегі нәтижелері көрсетілген. Негізгі мақалалардың басым көпшілігі PubMed, MEDLINE, CINAHL, Embase, e-library, Google Scholar базасында индексирленген.
Проспективный анализ сочетанной лучевой терапии местнораспространенного рака шейки матки в Кашкадарьинской области
Authors: У.Э. Убайдуллаев , Э.Р. Гафуров , Б.Т. Туланов , У.С. Раззоков
Published: October 2024

Настоящее исследование основано на результатах лечения 52 пациентов с местно-распространенной карциномой шейки матки. Проанализированы безрецидивная и общая годовая выживаемость пациентов, влияние некоторых факторов на показатели выживаемости. Анализ динамики комбинированной лучевой терапии местнора-спространенного рака шейки матки показывает, что общая годовая выживаемость составляет 98,1±0,8%, безрецидивная выживаемость – 69,2±1,7%. Установлено, что большая часть рецидивов возникает в течение первых 6–9 месяцев после первичного лечения. Выявлено влияние на сроки наблюдения некоторых факторов организма и опухоли, таких как репродуктивный возраст, стадия заболевания, поражение параметрия, непосредственные результаты лечения и степень лучевого патоморфоза.

The current study is based on treatment results of 52 patients with locally spread cervical carcinoma. Re- currence-free and overall one-year survival rate of patients, influence of some factors on indices of survivability have been analyzed. The analyses of follow-up of combined radiotherapy of locally spread cervical carcinoma shows that overall one-year survival rate is 98,1±0,8% and recurrence-free survival rate is 69,2±1,7%. It is de- termined that most part of recurrences occurs during the first 6-9 months after the initial treatment. Influence of some factors of an organism and a tumor as reproductive age, disease stage, parametrium involvement, direct treatment results and degree of radial pathomorphism on the follow-up has been detected.
NIVEL DE ACTIVIDAD FÍSICA Y ANSIEDAD EN ESTUDIANTES DE ENFERMERÍA DE TERUEL. UN ESTUDIO DESCRIPTIVO.
Authors: Soriano García Marta , Sancho Sinisterra Pablo
Published: October 2024

Introducción: La ansiedad se define como la emoción o sentimiento desagradable de temor e inquietud. El paso a la Universidad es una etapa de muchos cambios que pueden producir una mayor vulnerabilidad a algunas alteraciones mentales como la ansiedad. Los estudiantes universitarios tienen un alto riesgo de caer en un estilo de vida sedentario. Se ha decidido realizar este estudio sobre ansiedad y actividad física entre la población universitaria de enfermería de Teruel para determinar si existe relación entre ambas variables. Objetivo: Conocer si el nivel de ansiedad varía en función de la actividad física realizada en la población universitaria de enfermería de Teruel. Metodología: Se realizó un estudio observacional descriptivo transversal. La muestra estuvo compuesta por 66 estudiantes de la Escuela Universitaria de Enfermería de Teruel. Como instrumento de medida se empleó un cuestionario distribuído vía Whatsapp que incluía dos escalas validadas: el Cuestionario Internacional de Actividad Física (IPAQ) y el Inventario de Ansiedad de Beck (BAI). Se asumió un nivel de confianza del 95%. Se compararon variables cualitativas, valorando la p de la Asociación lineal por lineal. Resultados: Un 74,2% de los participantes que mostraron mínima ansiedad realizaron un nivel de actividad física alto. El 9,7% de los que realizaron un nivel de actividad física bajo experimentó mínima ansiedad. De los estudiantes con un nivel de actividad física alto, el 5% tuvo un nivel de ansiedad grave. Discusión: Los resultados hallados coinciden con los de otros estudios. Podría ser una buena idea llevar a cabo un Programa de Educación para la Salud enfocado a promocionar el ejercicio físico en estudiantes universitarios. Conclusión: Los universitarios que realizaron un mayor ejercicio físico experimentaron una menor ansiedad que los que realizaron una menor actividad física.
La juventud de un viejo partido. Sentidos de lo juvenil y relaciones intergeneracionales en la Unión Cívica Radical
Authors: Grandinetti Juan Rafael
Published: October 2024

Este artículo estudia los sentidos y usos partidarios de la juventud como categoría política en la Unión Cívica Radical de la Ciudad Autónoma de Buenos Aires. En primer lugar, aborda la juventud como principio de legitimación político-moral. Muestra que la militancia juvenil de este partido tradicional se presenta como la encargada de velar por la consistencia programática e identitaria del partido, en tanto heredera de sus “valores históricos”. Así, esta militancia cultiva la imagen de una juventud “crítica” y “rebelde”, capaz de alzar la voz ante la dirigencia del partido. En segundo lugar, el artículo aborda la juventud en su dimensión organizacional, como principio a partir del cual se distribuye el trabajo político y el poder entre generaciones. Al respecto, muestra que las estructuras del partido local y sus dinámicas de competencia interna fijan fuertes constricciones al momento de traducir los atributos político-morales de la juventud en prácticas políticas concretas. Los resultados presentados se basan en un trabajo de campo desarrollado entre 2017 y 2018, en el que se utilizaron métodos de recolección de datos cualitativos tales como entrevistas en profundidad, observaciones de campo y análisis de contenido de documentos y páginas web de la organización.
Economía y política. Disputas hegemónicas entre los actores de poder en torno al proyecto de expropiación del Grupo Vicentin durante el gobierno de Alberto Fernández
Authors: Fair Hernán
Published: October 2024

Este trabajo investiga los posicionamientos y disputas discursivas entre los actores políticos clave en torno al proyecto de expropiación del conglomerado Vicentin, durante el gobierno de Alberto Fernández (junio-julio de 2020). Como resultado del análisis empírico-discursivo, encontramos una intensa lucha hegemónica en torno al proyecto. Por un lado, hallamos un paquete de discursos que se expresaba a favor de la medida y se condensaba en la defensa de la soberanía alimentaria, el rescate de una empresa estratégica para regular los precios del mercado interno, controlar las divisas y evitar devaluaciones bruscas, preservar los puestos de trabajo y garantizar el pago a sus acreedores. Además, afirmaba que se trataba de una medida excepcional, destacaba que Vicentin se hallaba en quiebra y acusada de maniobras fraudulentas. Por el otro, encontramos un paquete discursivo contrario al proyecto, que invocaba como argumentos la inconstitucionalidad de la medida y sus efectos negativos sobre la seguridad jurídica y la confianza necesaria para atraer inversiones. Además, sostenía que todos los argentinos tendrían que hacerse cargo de la deuda de una empresa privada, catalogaban como una “excusa” la defensa de la soberanía alimentaria y consideraban que Argentina iba camino a un modelo “chavista”. En la última parte del artículo, abordamos el impacto hegemónico de la medida a nivel institucional y social, que derivó en protestas sociales y una judicialización de la política y concluyó en el bloqueo del proyecto.
Moderasi Beragama di Indonesia: Perspektif Filsafat Chuang Tzu
Authors: Fatlolon Costantinus
Published: October 2024

This article employs an expository-critical approach to Chuang Tzu‟s philosophical concept of equality of things and opinions. Its main purpose is to offer an alternative paradigm for religious moderation in Indonesia. The question that this article addressed is: “What is the relevance of Chuang Tzu‟s concept of the equality of objects and opinions for religious moderation in Indonesia?” This article finds that Chuang Tzu‟s philosophy provides an epistemological and metaphysical basis for religious moderation in Indonesia. Epistemologically, religions are the result of limited human contemplation, construction, and conception dealing with the Infinite Reality. Metaphysically, religions are equal because they originate from one and the same Infinite Reality. This epistemological-metaphysical frame guides different religions in Indonesia to maintain legal-formal commitments regarding the rights and freedoms of every citizen, accept differences and be flexible in religious insights, provide non-violent actions, and respect local wisdom. Finally, this article proposes that all problems that still hinder religious moderation in Indonesia can be solved through a humanist approach to radical religious groups, inter- and intra-religious dialogue, and dialogue between religion and local culture
Employee Determination Decision Support System at Pt. Pos Indonesia in Medan using the TOPSIS Method (Case Study: Mail Processing Center Office)
Authors: Sianipar Suryani
Published: October 2024

TOPSIS method is widely used to solve practical decision problems. the concept is simple and easy to understand, computationally efficient and has the ability to measure the relative performance of decision alternatives in a simple mathematical form. in this case the alternative in question is the determination of the right employees to run as a consideration that the company can improve based on the criteria of employees at PT. Pos Indonesia Medan. With this method, it is hoped that the assessment will be more precise because it is based on the criteria and weights that have been determined so that it will get more accurate results for the determination of employees to be carried out. This thesis will describe the decision support system for determining employees at PT.