bluuebunny/crossref_metadata_2025 huggingface dataset:
Genome Engineering in Livestock: Recent Advances and Regulatory Framework
Authors: Kumar Dharmendra , Kues Wilfried A.
Published: January 2023

Since the domestication of animals, livestock species are an important source of protein-rich food, and other animal products. The very recent progress in genetic engineering allows to modify the genomes of livestock species in an unprecedented way to improve productions traits, disease resistance, adaptation to climate changes, animal welfare aspects, but also to develop large animal models for developmental biology and biomedicine. Here, we concisely summarize the recent progress of genome-editing technologies, with a particular focus on the CRISPR/Cas9 designer nuclease, in livestock. Currently, precision-modified livestock lines with disease resistance and production traits are ready to be introduced into the commercial production. On a scientific basis these lines are considered safe for human consumption, especially for genome edits implementing only a single nucleotide change, which mimic ´natural´ point mutations. Internationally, however, there are clear differences in the interpretation of the legal framework on whether genome edited animals or their products need to be regulated.
The impact of the G-code flavour selection in FFF
Authors: Eva Silviu-Cristian , Sover Alexandru , Ermolai Vasile
Published: January 2023

Fused Filament Fabrication has become one of the most popular additive manufacturing technologies due to many hardware options and materials at affordable prices. A reason for its success is the open-source status of the technology. This allowed both professionals and amateurs to contribute to the development of material extrusion technology. Furthermore, a wide range of available equipment brought slicing software developers to improve the user experience by expanding the equipment library and making the interface user-friendly and intuitive. In order to successfully print a part, the printer's firmware must interpret a compatible G-code file generated by a slicer. For this reason, each slicing software has multiple G-code flavours available to match the equipment. This paper aimed to evaluate the influence of all G-code flavours available in Cura slicing software by using a benchmark model. The evaluation refers to the resulting models' G-code characteristics analysis and print quality. The results show that the printed models' quality depends on G-code flavour and equipment.
Evaluation of coronary arteries in congenital heart disease
in children: diagnostic comparison of electrocardiogram-gated and non-electrocardiogram-gated computed tomography cardiac angiography
Authors: Sodhi Kushaljit Singh , Bhatia Anmol , Rana Pratyaksha , Farook Shameema , K. Saxena Akshay , Baryah Harkant S. , Mishra Anand K. , Manoj Rohit
Published: January 2023

Introduction

To compare the visualization and anatomy of coronary arteries in children (≤ 2 years) with congenital heart disease (CHD) on non-electrocardiogram (ECG)-gated and ECG-gated computed tomography angiography (CTA).

Material and methods

In this retrospective study, approved by the Ethics Committee of our institute, evaluation of coronary arteries in CHD was performed in 40 children on non-ECG-gated CTA and in 42 children on ECG-gated CTA. The origin and course of the right coronary artery (RCA), left main coronary artery (LMCA), left anterior descending (LAD) artery, and left circumflex (LCX) artery were evaluated by 2 paediatric radiologists independently.

Results

ECG-gated CT scans yielded increased (additional) visualization of all the coronary arteries, when compared to non-ECG-gated CT scans. The RCA, LMCA, LAD artery, and LCX artery were visualized in 47.5%, 62.5%, 55%, and 32.5% of children, respectively, on non-ECG-gated studies, while they were visualized in 64.3%, 92.8%, 80.9%, and 62% children, respectively, on ECG-gated studies. The coronary artery anatomical variations were also supplementarily detected more in the ECG-gated group (23.8%) than in the non-ECG gated group (2.5%).

Conclusions

ECG-gated CT cardiac angiography studies yield enhanced diagnostic outcomes for the evaluation of the coronary arteries in comparison to non-ECG-gated studies.
Friend-shoring: A Major Turning Point Towards more Sustainable Value Chains?
Authors: Paché Gilles
Published: January 2023

The concept of friend-shoring, which appeared in April 2022, could contribute to a profound transformation of international trade and, more surprisingly, prevent the environmental crisis from continuing. Friend-shoring, a contraction of “friends” and “offshoring”, suggests developing partnerships with close friend countries, stopping the relocation of industrial activities to the other side of the planet based solely on the criterion of low labour costs. The key idea is to build regional value chains, which could ultimately be much more sustainable. The objective of this short communication is to highlight the conditions of appearance of the friend-shoring concept and its main economic and environmental issues in a value chain perspective, and then to insist on the limits of its implementation. Given the current absence of friend-shoring experiments, the chosen methodology relies on a speculative approach based on the exploration of scientific knowledge about regional supply chains.
Los informes motivados vinculantes como instrumento para la interpretación y aplicación de los incentivos fiscales a la innovación
Authors: Fabra Valls Modesto
Published: January 2023

En el trabajo se analizan los informes motivados vinculantes expedidos para dotar de seguridad a los contribuyentes en la calificación de las actividades que dan derecho a los incentivos fiscales a la innovación, así como para clarificar otros aspectos como la adscripción en exclusiva de los investigadores a las citadas actividades. Al igual que ocurre con carácter general (mediante instrumentos como las consultas o los acuerdos previos de valoración) el sistema tributario español permite obtener pronunciamientos previos vinculantes. Sin embargo, en relación con la deducción en la cuota por I+D+i los citados pronunciamientos no se expiden por la Agencia Tributaria o por la Dirección General de Tributos sino que su emisión corresponde al ministerio con competencias en ciencia y tecnología (actualmente el Ministerio de Economía, Industria y Competitividad).
Estos informes motivados, vinculantes respecto a la calificación de las actividades, han permitido que la deducción en la cuota por actividades de I+D+i se consolide como un importante instrumento de financiación de la innovación empresarial. Sin embargo, presentan diversos aspectos susceptibles de mejora. El principal de ellos, las dudas que se suscitan respecto a los efectos que despliegan los distintos tipos de informes y la relación entre ellos. Además, utilizan con carácter general un procedimiento que implica la revisión en cada una de las anualidades de los gastos ejecutados, cuando el informe únicamente va a ser vinculante en cuanto a la calificación de las actividades, aspecto que puede introducir costes y dilaciones innecesarias. También se analizan los acuerdos previos de valoración que se utilizan en relación con el patent box, que son expedidos por la Dirección General de Tributos, así como las diferencias y relaciones entre los distintos instrumentos.
Effect of nitrogen fertilizers on the growth, development and yield of new varieties of spring triticale (×Triticosecale Wittm.)
Authors: Alenicheva Anastasia , Shchuklina Olga , Kvitko Valeria , Klimenkova Irina , Gruzdev Ivan , Langaeva Natalia , Garibyan Tsovinar , Zavgorodniy Sergey
Published: January 2023

Triticale (×Triticosecale Wittm.) is a fairly new grain and fodder crop. Promising varieties of spring and winter types require a certain approach and study of the elements of cultivation technology in specific soil and climatic conditions. This is especially true for the use of energy-intensive products, such as mineral fertilizers and plant protection products. The studies were carried out under conditions of sod-podzolic heavy loamy soils with low humus content (1.4-2.0%). The objects of the study were varieties of spring triticale included in the State Register of Breeding Achievements in 2022: Timiryazevskaya 42 and Botanicheskaya 4 (originators are FSBIS ARRIAB and FSBIS MBG RAS). Modern varieties have been shown to be highly responsive to nitrogen fertilization. With an average grain yield without fertilization of 4.45-4.89 t/ha, they respond with increases ranging from 2.74 to 5.10 t/ha (Timiryazevskaya 42) and from 1.11 to 2.71 (Botanicheskaya 4). Under the prevailing meteorological conditions, the maximum grain yield was obtained on the Timiryazevskaya 42 variety with the application of 150 kg of active substance per hectare (9.99 t/ha), on the Botanicheskaya 4 variety with the application of 90 kg of active substance per hectare (7.16 t/ha). Keywords: TRITICALE, NITROGEN FERTILIZERS, DRESSING, NITROGEN, MINERAL NITRITION, YIELD, GRAIN
Capturing synoptic-scale variations in surface aerosol pollution using deep learning with meteorological data
Authors: Feng Jin , Li Yanjie , Qiu Yulu , Zhu Fuxin
Published: January 2023

Abstract. The estimation of daily variations in aerosol concentrations using meteorological data is meaningful and challenging, given the need for accurate air quality forecasts and assessments. In this study, a 3×50-layer spatiotemporal deep learning (DL) model is proposed to link synoptic variations in aerosol concentrations and meteorology, thereby building a “deep” Weather Index for Aerosols (deepWIA). The model was trained and validated using 7 years of data and tested in January–April 2022. The index successfully reproduced the variation in daily PM2.5 observations in China. The coefficient of determination
between PM2.5 concentrations calculated from the index and observation
was 0.72, with a root mean square error (RMSE) of 16.5 µg m−3. The DeepWIA performed better than Weather Forecast and Research (WRF)-Chem simulations for eight aerosol-polluted cities in China. The simulating power of the model also outperformed commonly used PM2.5 concentration retrieval models based on random forest (RF), extreme gradient boost (XGB), and multilayer perceptron (MLP). The index and the DL model can be used as robust tools for estimating daily variations in aerosol concentrations.
Significant underestimation of peatland permafrost along the Labrador Sea coastline in northern Canada
Authors: Wang Yifeng , Way Robert G. , Beer Jordan , Forget Anika , Tutton Rosamond , Purcell Meredith C.
Published: January 2023

Abstract. Northern peatlands cover approximately four million
km2, and about half of these peatlands are estimated to
contain permafrost and periglacial landforms, like palsas and peat plateaus.
In northeastern Canada, peatland permafrost is predicted to be concentrated
in the western interior of Labrador but is assumed to be largely absent
along the Labrador Sea coastline. However, the paucity of observations of
peatland permafrost in the interior, coupled with traditional and ongoing
use of perennially frozen peatlands along the coast by Labrador Inuit and
Innu, suggests a need for re-evaluation of the reliability of existing
peatland permafrost distribution estimates for the region. In this study, we
develop a multi-stage consensus-based point inventory of peatland permafrost
complexes in coastal Labrador and adjacent parts of Quebec using
high-resolution satellite imagery, and we validate it with extensive field
visits and low-altitude aerial photography and videography. A subset of 2092
wetland complexes that potentially contained peatland permafrost were
inventoried, of which 1119 were classified as likely containing peatland
permafrost. Likely peatland permafrost complexes were mostly found in
lowlands within 22 km of the coastline, where mean annual air temperatures
often exceed +1 ∘C. A clear gradient in peatland permafrost
distribution exists from the outer coasts, where peatland permafrost is more
abundant, to inland peatlands, where permafrost is generally absent. This
coastal gradient may be attributed to a combination of climatic and
geomorphological influences which lead to lower insolation, thinner
snowpacks, and poorly drained, frost-susceptible materials along the coast.
The results of this study suggest that existing estimates of permafrost
distribution for southeastern Labrador require adjustments to better reflect
the abundance of peatland permafrost complexes to the south of the regional
sporadic discontinuous permafrost limit. This study constitutes the first
dedicated peatland permafrost inventory for Labrador and provides an
important baseline for future mapping, modelling, and climate change
adaptation strategy development in the region.
Potential of various trap crops for the control of Bemisia tabaci on chilli pepper
Authors: Sataral Mihwan , Daud Syahril , Fahri  , Hevianti Maria
Published: January 2023

The whitefly Bemisia tabaci is an important pest of chilli peppers and a vector insect that causes yellow leaf disease. This study aimed to compare the whitefly population and the intensity of its attacks on chilli production in plots with or without trap crops. This study used eggplant, tomato and mungbean as trap crops. As the main crop, Chilli pepper was planted in plots measuring 7 m x 4 m with a spacing of 60 cm x 70 cm. Trap crops were planted around the chilli pepper plots, with 16 plants in each plot. The results showed a significant difference between whitefly populations and the intensity of their attacks in plots without trap crops and plots with mungbean traps. The biggest chilli weight was obtained from plots with mungbean trap plants. State that mungbean has the best potential as a trap crop to control B. tabaci.
Verification of the humic substances and PGPB biostimulants beneficial effects on the potato yield and bioactive substances content
Authors: Andrejiová Alena , Adamec Samuel , Hegedűsová Alžbeta , Hegedűs Ondrej , Rosa Robert
Published: January 2023

Potatoes are one of the most important sources of nutrients worldwide, but excessive doses of industrial fertilizers are usually used to achieve higher yields. Soil biostimulants are an increasingly used alternative for reducing fertilizer doses and growing healthy agricultural products. In this study, we examined the effects of humic substances (Agriful) and beneficial bacteria (Groundfix) based biostimulants applied by dripping irrigation on the yield and quality of potato tubers in comparison with the conventional N fertilization system. The small trail field experiment was founded in the growing season of 2020 in the Botanical Garden of the Slovak University of Agriculture in Nitra. The highest tubers yield had the combination of biostimulants and N fertilizer – 195.16% above to control. Simultaneously this combination reached an increase in refractometric dry matter content, starch content – 3.6%, and vitamin C content – 20% increase above to control. The Groundfix variant had the highest antioxidant activity with a 16.2% difference compared to the conventional nitrogen fertilization variant. These results show the positive effect of applied biostimulants on the yield and quality of cultivated potatoes.
Benthic foraminiferal morphogroups from the Paleocene of the coastal part of East Stara Planina Mts.
Authors: Valchev Boris
Published: January 2023

Twelve morphogroups were defined on the basis of test shape and nature of test coiling as a result of the investigation of the Paleocene benthic foraminifera from the coastal part of East Stara Planina. The morphogroups are rounded trochospiral (RT), plano-convex trochospiral (PT), biconvex trochospiral (BT), milioline (M), rounded planispiral (RP), lenticular (L), flattened ovoid (FO), tapered and cylindrical (T/C), spherical (S), flattened tapered (FT), tubeshaped (T), streptospiral and heteromorphous (S/H). The previously described Byala-type and Flysh-type assemblages differ from each other by the predominant test morphology. There is no strongly dominating morphogroup in the Byala-type, while the Flysh-type is strongly dominated by two morphogroups. Both Byala-type and Flysh-type are dominated by morphogroups typical for deep sea conditions.
Stratigraphic problems of the Moesian Group (Upper Triassic, peri-Tethyan type), Bulgaria
Authors: Zagorchev Ivan , Budurov Kiril
Published: January 2023

The Moesian Group consists of terrigenous and carbonate red beds of different lithology. Conglomerate and sandstone of various pebble and grain size are interbedded with siltstone, shale and marl. Limestone or dolomite interbeds are also observed as well as lenses and concretions of anhydrite, and halite bodies. The formations of the group are referred to parts of the Upper Triassic on the basis of marine fossil faunas found. The introduction of lithostratigraphic units (formations and members) is based upon the predominance of one, two or more lithologic components. The end members of the lithologic range (the carbonates and the psephytic sediments) form in some cases almost uniform lithologic (lithostratigraphic) bodies. The Chelyustnitsa Formation is introduced herewith as a specific and independent lithostratigraphic unit. It consists of dominant red conglomerates built up almost exclusively of rounded or angular to semi-rounded fragments of Middle Triassic carbonate rocks and Lower Triassic and Permian red sandstones and siltstones. The thickness of the formation is between 300 and 500 m. Most probably the formation was interfingering with and wedging out fast within the Komshtitsa Formation. The present outcrops of the formation are situated north of the villages of Chelyustnitsa and Belimel as well as south-east of the village of Gavril Genovo and south and west of the village of Gaganitsa. They are in the shape of thick lenses covered by Jurassic and/or by younger formations. The defining features are the coarse lithology and the pebble composition. The formation originated from the fast deposition of fans of coarse terrigenous material supplied from adjacent uplifting island horsts within the regressing Late Triassic sea.
Attempt for Upper Cretaceous planktic foraminiferal zonation of the Srednogorie and Eastern Balkan Zones (Bulgaria)
Authors: Dimitrova Ekaterina , Valchev Boris
Published: January 2023

Thirteen biostratigraphical zones were defined as a result of summarizing of the available data on the taxonomy, stratigraphical range and occurrence of the Upper Cretaceous planktic foraminifera from the Srednogoriå and East Balkan. The zones are: Rotalipora cushmani Taxon Range Zone (Late Cenomanian), Dicarinella imbricata Interval Zone (Early Turonian), Marginotruncana renzi – Marginotruncana sigali Interval Zone (Middle Turonian), Marginotruncana schneegansi Interval Zone (Late Turonian), Dicarinella primitiva Interval Zone (Early Coniacian), Dicarinella concavata Interval Zone (Late Coniacian to Early Santonian), Globotruncanita elevata Interval Zone (Early Campanian), Globotruncanita stuartiformis Interval Zone (Early Late Campanian), Radotruncana calcarata Taxon Range Zone (Late Late Campanian), Globotruncana falsostuarti Interval Zone (Early Maastrichtian), Contusotruncana contusa Interval Zone (Early to Late Maastrichtian), Abathomphalus mayaroensis Taxon Range Zone (Late Late Maastrichtian). The zones were successfully correlated to the biostratigraphical schemes in the Carpathians, Mediterranean Basin, Caribbean Basin, and some generalized zonations.
Evidence for the Aeolian Origin of Loess in the Danubian Plain
Authors: Evlogiev Yordan
Published: January 2023

The present work considers the evidences for the Aeolian origin of loess in the Danubian plain, put forward by previous authors, which have been amended with results from new investigations. One of the main proofs consists in the grain-size composition changes of the loess complex from north to south, from east to west and with depth. Other evidences are the well expressed directions of loess winnowing in the Danubian plain: from west-northwest and north-northeast. The next evidence for the Aeolian origin of loess is the sequence in the loess accumulation process. It was started before 2.59 Ma BP along the coast of the Dacian basin and after its regression loess winnowing was also spread on the occupied by the basin territories (0.82 Ma BP). The loess complex becomes younger towards the Danubian terraces. The deflation of the loess fine earth material occurred from the flooded areas of the Paleodanube River and its tributaries, from the Black sea shelf and the clayey alluvium of the Dacian basin. The orientation of the deflation area with respect to the transporting Aeolian corridor was one of the reasons for the differences in the lithostratigraphy and the thickness of the loess complex. Five loess regions were differentiated in the Danubian plain: Northeast, “Yantra-Vit”, “Vit-Ogosta”, “Ogosta-Lom” and the Black Sea region.
Lithostratigraphy of the Upper Cretaceous Series in a part of the Krayshte area (Southwest Bulgaria)
Authors: Ivanov Marin , Stoykova Kristalina , Zagorchev Ivan , Goranov Emil
Published: January 2023

The Upper Cretaceous sediments in Krayshte area are reported to have a wider distribution than previously considered. They are dated using calcareous nannofossils, proving the presence of different parts of the Campanian Stage. Four new formal lithostratigraphic units are introduced and characterized. The Gorna Koznitsa Formation consists of coarse siliciclastic rocks and is probably of Early Campanian Age. The Gorno Gabreshevo Fm. is represented by rhythmic turbidites of Early to Late Campanian Age. The Uglyartsi Fm. is dominated by fine grained sediments – marls, finely laminated claystones and clayey limestones. Its age is Campanian, too. These three units are widespread in the area. The last unit, Shabanitsa Fm., is locally developed in the eastern part of the area. It is built up by loose siliciclastic and mixed hypo-rocks, including non-marine sediments –oncoid limestones and stromatolites of Late Campanian Age. The Upper Cretaceous sediments were deposited most probably in a tectonically controlled asymmetric basin (Babushnitsa-Fucha basin – Zagorchev et al., 2006). The sediments in the eastern parts of the basin exhibit the greatest variety. The coarse clastic sequences cover transgressively over the northern board of the basin, and are covered by predominantly marly deposits. Westwards, they are gradually replaced by marly and carbonate sediments that probably pass to the north into the limestone sequences typical for the western parts of the basin on the territory of Serbia.
Alteración de la microbiota intestinal y su relación con enfermedades gastrointestinales y hepatobiliares
Authors: Villalobos-Orozco Mervin W.
Published: January 2023

La interrupción de la simbiosis que existe entre el cuerpo humano y su microbioma puede resultar en una disbiosis, un desequilibrio en la interacción huésped-microbiota, que puede asociarse al desarrollo de diversas enfermedades como el síndrome de intestino irritable, hígado graso no alcohólico, enfermedad hepática alcohólica y cirrosis, entre otras. En ciertas condiciones patológicas y por múltiples factores de riesgo, la capacidad de autorregulación del intestino se puede alterar, contribuyendo al incremento de la permeabilidad con inflamación intestinal crónica. El diagnóstico y el tratamiento, así como la relación entre la permeabilidad intestinal, la disbiosis y las patologías gastrointestinales y hepatobiliares, todavía no tienen estudios clínicos validados o con el soporte científico adecuado, por lo que se realiza una revisión de la literatura con la finalidad de aportar conceptos que puedan orientar con respecto a la importancia del estudio del microbioma humano en estas enfermedades.
ASSESSMENT OF THE GENERAL LEVEL OF DAMAGEABILITY TO INSULATION COATINGS OF STEEL UNDERGROUND GAS DISTRIBUTION PIPELINES
Authors: ROMANIUK V. , STRUTSKY N.
Published: January 2023

The article presents the results of analysis of long-term dynamics of damage of protective coatings of distribution gas pipelines revealed in the process of operation. The applied methodology of complex instrumental inspection and diagnostics of insulation is highlighted. The estimation of the general level of damageability of protective coverings on the basis of the value of specific density of defects was carried out. The received results testify to an insignificant degree of wear and absence of signs of approaching the limit state of gas pipelines' insulating coatings, including those being in operation for more than 40 years. This is an additional argument in favor of revising the normative service life of steel distribution gas pipelines towards increase.
METHODS FOR REMOTE QUALITY CONTROL OF COMPOSITES WITH ORGANIC AGGREGATES
Authors: YAGUBKIN A. , ZHIXU Z.
Published: January 2023

The Chinese construction industry has been using the Internet of Things (IoT) to monitor building materials and structures for many years. The achievements of the Chinese construction industry in IoT applications can be used to study and monitor the performance of building materials, including green buildings (energy-efficient building materials).
The aim of research: study and optimization methods for remote quality control of composites with organic aggregates.
With the help of the developed methods, the following dependencies were obtained: dependences of stresses inside composites with organic aggregates on external influences obtained using a sensor Keyes brick thin film pressure sensor, dependences of deformations inside composites with organic aggregates on external influences obtained using a sensor ultrasonic ranging sensor, dependences of humidity inside composites with organic aggregates on external influences obtained using a sensor Soil moisture sensor, dependences of rheology (cement paste setting time) obtained using a sensor Ph-sensor module.
Impacto del entorno digital en los medios tradicionales chilenos: percepciones y actitudes predominantes de sus protagonistas
Authors: González-Trujillo Rocío , Olate-Hidalgo Catalina , Grassau Daniela
Published: January 2023

El artículo investiga las transformaciones provocadas por el entorno digital y las redes sociales dentro de las salas de redacción de medios tradicionales chilenos. Se enfoca en tres aristas: el impacto del entorno digital en el ejercicio del periodismo, el uso de redes sociales en los medios tradicionales y las oportunidades y los riesgos para las rutinas profesionales. Para ello se condujo un estudio cualitativo a partir de 21 entrevistas en profundidad semiestructuradas con el objetivo de explorar las percepciones de los protagonistas. En cuanto a los resultados, se observa que, si bien el entorno digital ha puesto en tensión la función tradicional del periodismo como guardianes de la información (gatekeepers), sus aspectos fundamentales siguen vigentes como pilares de la profesión con el fin de preservar estándares de calidad. Los periodistas y medios tienden a ver ciertas redes sociales –p. ej. Twitter, Facebook e Instagram– como plataformas para agilizar su trabajo y aumentar su alcance, pese a que reconocen riesgos y amenazas que tensionan su independencia, provenientes principalmente de la presión de la audiencia. Por último, se evidencia que los medios están ocupando múltiples estrategias y protocolos para enfrentar los peligros que conlleva el entorno digital.
ANALYSIS OF GENETIC VARIANCE FOR MILK PRODUCTION AND IT COMPONENTS IN LOCAL GOAT FOR PROLACTIN RECEPTOR GENE
Authors: AL Khazraji Wasan J. , AL-Khuzai Hamza M. , AL-Shaikh May A.
Published: January 2023

The current study was conducted in Ruminant research station belong to the Minister of Agriculture Iraq by using 50 dies to estimate the breeding value and additive or dominant variance as well as the effect of gene substitution of PRLR gene depending on the information of (SNPs) which determined by (RFLP), Results showed three genotypes in the location that studded and breeding values were 3.544,0.818 and -1.91 MM, MN and NN Respectively, Dominance devotion -1.0207, 0.465 and -0.2988 Respectively, Genetic variance value (4.11943) while Additive variance value (3.812) and Dominance variance value (0.3082). Results showed that the average gene substitution from M to N was 2.776 and the average gene substitution at N to M was -2.726. Results referred to the importance at selection towards the M alle and against the N alles to increase the animal number that carrying the Mallele in herd which reflex positively on milk production.
CADMIUM TOXICITY IN PLANTS: REMEDIAL STRATEGY THROUGH SEED PRIMING
Authors: NAIK MOHIT , AKASH  , KUMAR DEEPAK , SINAM VIKASH , SIDDIQUE ANAYTULLAH
Published: January 2023

Heavy metals (HMs) Hg > Cd> Pb> As> Ag> Ni > Co > Cu > Zn is the most popular environmental pollutants known since a long time ago as a major environmental threat; Cd is one of them. It has around 25-30 years of persistence in the environment, therefore, poses a hazardous impact on entire living things on the planet including plants, animals and human beings. Anthropogenic activities such as urban waste disposal, smelting, mining and the use of synthetic phosphate fertilizers are the major source of Cd in the soil. Plants grown in Cd-contaminated soil absorb the heavy metal through their roots and accumulate in different parts of the plant consequently limiting the entire phase of plant growth and development. It reduces the potential of water and nutrient uptake while it accelerates the production of reactive oxygen species (ROS) and oxidative damage to the cell membrane. Seed priming may be a dynamic approach to overcome phytotoxicity caused by the presence of cadmium more than the threshold level which is (3-5 mg g-1). Seed priming with various salts such (KNO3 , Mg (NO32) and Ca (NO32) and Growth hormones(Auxin, GA3 and Salicylic acid) participate in the betterment of seed germination, seedling establishment till the maturity of the crop by improving the defense system against the Cd toxicity.
Application of Different Types of Nanoparticles in Cancer Early Diagnosis and Therapy
Authors: Choubey Madhu Harkesh
Published: January 2023

Cancer is one of the highest leading causes of human death across the globe. This current scenario of increasing cancer deaths poses a need to explore more effective cancer diagnosis and treatment methods. The use of nanotechnology in medicine, one of the most advanced fields of scientific research, has become a boon for cancer patients. Nanomedicine has been proven to be one of the most revolutionary alternatives with its extraordinary characteristics such as high selectivity, high specificity, targeted anti-cancer drug delivery approach, drug-receptor binding, cell-receptor binding, low toxicity, renal purification, bio-compatibility, immune compatibility, and cancerous cells identification. This review article aims to present a clear understanding of the various types of nanoparticles such as carbon nanotubes, nano quantum dots, nanoshells, and metallic nanoparticles used for the early diagnosis and treatment of cancer. Specially designed nanoparticles offer superior merits compared to conventional cancer detection and treatment methods. Nanomedicine has applied its innovative ideas and unique characteristics in the vast field of cancer biology. In addition, an in-depth study of the main types of nanoparticles currently available for higher and more effective cancer diagnosis and treatment, as well as their future scope, is also examined.
TÜRK CEZA YARGILAMASINDA İSTİNAF MAHKEMESİ KARARLARININ KESİN NİTELİĞİ VE KANUN YOLLARINA BAŞVURU
Authors: ATALAN Mustafa
Published: January 2023

İlk derece mahkemesi kararlarına karşı teminat ve bir üst kanun yolu olarak tasarlanan istinaf, ülkemizdeki ceza yargılama sistemini, iki dereceli bir sistemden, belli kararlar açısından üç dereceli bir sisteme geçişin zeminine taşımıştır. Böylece, ilk derece mahkemesi tarafından verilen hükümlere karşı, ilk başvurulması gereken kanun yolu, istinaf olarak belirlenmiştir. İstinaf mahkemeleri tarafından verilen kararlardan bir kısmı, kesin olarak, bir kısmı da belli koşullar altında, Yargıtay yolu açık olmak üzere verilmektedir. Bu şekilde oluşturulan sistemle, belli kararlar açısından iki dereceli, belli kararlar açısından da üç dereceli bir yargılama sistemi benimsenmiştir. Bu çalışmamızda, hangi kararların bölge adliye mahkemelerinde kesinleştiği, hangi kararların temyize tabi olduğu, bu şekilde farklı iki sistemin öngörülmesinin, bireylerin, hak arama özgürlüğünü ne şekilde etkilediği hususları ve bu konudaki çözüm önerileri değerlendirilecektir.
Design e ciência:
Authors: Valentim Matheus Augusto Gomes
Published: January 2023

Desde sua gênese, o design convive com um desejo de seus acadêmicos em vê-lo aproximado do saber científico. Fazendo um percurso pelo século XX, partindo das vanguardas modernas, inauguradoras da disciplina, este artigo buscou fazer um panorama de como a relação com a ciência foi abordada por determinados grupos do design. Ao fim, foi feita uma exposição desse debate na contemporaneidade, utilizando-se do diálogo estabelecido entre Robert Farrell, Cliff Hooker, Per Galle e Peter Kroes. Os argumentos utilizados pelos autores foram analisados através da discussão da coisa em si, conceito presente na filosofia de Immanuel Kant que fora posteriormente criticado por Friedrich Hegel. Através do desenvolvimento hegeliano para a questão, este artigo pôde estabelecer uma posição de que o design não encontra caraterísticas suficientes para ser considerado ciência.
Vivendo no Sufocamento
Authors: Miranda Samuel da Silva , Batista Marcelo Viana , Sklovsky Fernanda Galvão , Meyer Guilherme Englert Corrêa
Published: January 2023

Vivemos em tempos de crises. O design, a partir das práticas convencionais, contribuiu para a amplificação de determinados desequilíbrios. Conscientes e posicionados em práticas disruptivas, propomos neste artigo a experimentação enquanto meio de o design oportunizar outros modos de ação, atuando em subversividade aos modos tradicionais de solucionar o problema da crise e elaborando alternativas para vivermos nela. Conduzimos uma prática experimental de construções narrativas de vida em crise, por meio de cards especulativos, atravessando possibilidades para se pensar a crise. Na oportunidade, os praticantes experimentais foram imersos em perspectivas de viver em tempos de sufocamento, estimulados pelas dinâmicas propostas. Este artigo apresenta um relato da prática experimental, em que foram postas maneiras para pensar uma crise, resultando num estímulo ao pensamento criativo e crítico em design sobre os modos de contribuição com a temática.
A method for parameter estimation of a multichannel measuring system
Authors: M.M. Isayev, , F.Sh. Agayeva, , N.M. Khasayeva,
Published: January 2023

High accuracy of multichannel information measuring systems depends on correct determination of parameters of information traffic channels and sensor management. At the same time, the development of information systems depends on the reliability and subsequent processing of the collected information. For this purpose, an analysis of the specifics of a multichannel measuring system is given and a testing algorithm and optimal structure for high-precision determination of the parameters of information traffic channels are developed.
An algorithm of position-binary technology for controlling the beginning and dynamics of accidents of sucker rod pumping units
Authors: T.A. Aliev, , G.A. Guluyev, , As.G. Rzayev, , M.G. Rezvan,
Published: January 2023

In recent years, diagnostics of the state of an object using the NOISE technology has shown incomparable advantages in recognizing state changes and has been widely used in various fields. It is important here to determine the beginning of a change in the technical condition and the dynamics of its development before the accident. The article deals with the problem of determining the onset of an accident and its dynamics of development in the technical condition of sucker rod pumping units in oil production by mechanized methods. We propose algorithms for calculating the estimates of informative attributes of a cyclic signal, both decomposed into position-binary components and saved in the form of an array, and in the course of measurement and analog-to-digital conversion without saving. Real dynamometer charts of sucker rod pumping units are taken as signals.
Transfer learning for Azerbaijani Sign Language Recognition
Authors: G.G. Abdullayeva, , N.O. Alishzade,
Published: January 2023

The goal of sign language technologies is to develop a bridging solution for the communication gap between the hearing-impaired community and the rest of society. Real-time Sign Language Recognition (SLR) is a state-of-the-art subject that promises to facilitate communication between the hearing-impaired community and others. Our research uses transfer learning to provide vision-based sign language recognition. We investigated recent works that use CNN-based methods and provided a literature review on deep learning systems for the sign language recognition (SLR) problem. This paper discusses the architecture of deep learning methods for SLR systems and explains a transfer learning application for fingerspelling sign classification. For the experiments, we used the Azerbaijani Sign Language Fingerspelling dataset and got 88.0% accuracy.
Геоэлектросканирование с использованием ближних наземных молний
Authors: Матевосян А. К.
Published: January 2023

Обсуждаются результаты впервые выполненных научно-исследовательских и опытно-методических геоэлектрических режимных наблюдений грозовых процессов в геологической среде на специально подготовленном геофизическом микрօполигоне с применением аппаратно-программного комплекса «VectorGeo». Представлена и проанализирована методика нового направления электро-разведочных работ основанного на применении электрических разрядов ближних наземных молний (мгновенного гиперсильного естественного электрического поля) с целью геологогео изических исследований земной коры которая послужит основой для дальнейшего развития глубинной векторной электроразведки – ГеоЭлектроСканирования.
Քննարկվում են երկրաբանական միջավայրում կայծակնային պրոցեսների գիտահետազոտական և փորձնամեթոդական երկրաէլեկ-տրական ռեժիմային դիտարկումների արդյունքները, ստացված «VectorGeo» սարքածրագրային համալիրի միջոցով հատուկ նախապատրաստված երկրաֆիզիկական միկրոփորձադաշտում: Ներկայացված և վերլուծված է էլեկտրահետախուզական աշխատանքների նոր ուղղության մեթոդիկան, որը հիմնված է կայծակի էլեկտրական լիցքաթափումները գետնին (ակնթարթային գերուժեղ բնական էլեկտրական դաշտի) օգտագործման վրա, երկրակեղևի երկրաբանա-երկրաֆիզիկական ուսումնասիրությունների համար, ինչը հիմք կհանդիսանա խորքային վեկտորական էլեկտրահետախուզության հետագա զարգացմանը` ԵրկրաԷլեկտրաՍկանավոր-մանը:
The article dicusses the results of the research and empirical geo-electric regime observations of the thunderstorm processes in the geological environment through the acquired “VectorGeo” hardwarde-software complex at the specially prepared geophysical micro-test site. The methodology of a new direction of electrical exploration works based on the application of electric discharges of on-ground lightnings (instantaneous hyper-strong natural electric field) for the purpose of geological-geophysical research of the earth's crust is presented and analyzed, which will serve as the basis for the further development of deep vector electrical exploration – GeoElectroScanning.
The recent 2021 yerevan earthquake (ml=4.9) in the seismotectonic context of the yerevan fault
Authors: Sargsyan L. , Sahakyan E. , Levonyan A. , Demirchyan H. , Toghramadjian N. , Gevorgyan M. , Bayraktutan M. S.
Published: January 2023

The earthquake of February 13, 2021 earthquake was the strongest earthquake ever reported in the vicinity of Armenia’s capital city of Yerevan in the modern instrumental time period. It was strongly felt throughout Yerevan and the surrounding areas. In this study, we analyze the source parameters and focal mechanism of this earthquake. Our calculated focal mechanism solution shows that this 2021 M4.9 earthquake is characterized by a thrust fault mechanism with a strike-slip component. We also discuss historical seismicity that has occurred over the course of a century in direct proximity to Yerevan, and demonstrate that the Yerevan Fault and Parakar sub-fault are seismically active systems. We also address the problem of possible NW and SE extensions of the Yerevan fault.
Ժամանակակից գործիքային ժամանակաշրջանում՝ 2021թ փետր-վարի 13-ի երկրաշարժը, ըստ հաղորդագրությունների, ամենաուժեղն էր Հայաստանի մայրաքաղաք Երևանում երբևիցե տեղի ունեցածներից: Այն ուժեղ զգացվում էր ամբողջ Երևանում և նրա շրջակայքում: Վերածվել է երկրաշարժի օջախի պարամետրերը և ֆոկալ մեխանիզմը: Մեր կողմից հաշվարկված ֆոկալ մեխանիզմը ցույց է տալիս, որ 2021թ M4.9 մագնիտուդով այդ երկրաշարժը բնութագրվում է կողաշարժի բաղադրիչ ունեցող վրաշարժի խզվածքի մեխանիզմով: Այդ, քննարկվել է Երևանի անմիջական մոտակայքում մեկ դարի ընթացքում տեղի ունեցած պատմական սեյսմիկությունը և ցույց է տրվել, որ Երևանյան խզվածքը և Փարաքարի ենթախզվածքը սեյսմիկորեն ակտիվ համակարգեր են: Անդրադարձ է կատարվել Երևանյան խզվածքի հնարավոր Հս.-Արմ. և Հվ.-Արլ. շարունակության խնդրին:
По сообщениям за современный инструментальный период времени землетрясение 13 евраля 2021 года было самым сильным событием в окрестности столицы Армении – Еревана. Оно сильно ощущалось по всему Еревану и на окружающих территориях. В данном исследовании мы анализируем параметры очага и окальный механизм этого землетрясения. аш расчет окального механизма показывает что это землетрясение 2021г. с магнитудой M4.9 характеризуется надвиговым механизмом с компонентой сдвига. Мы также обсуждаем историческую сейсмичность за столетие в непосредственной близости к Еревану и показываем что Ереванский разлом и Паракарский субразлом являются сейсмически активными системами. Мы также рассматриваем проблему продолжения Ереванского разлома на СЗ и на ЮВ.
DAKWAH SALAFIYAH: DIALEKTIKA MASYARAKAT BERAGAMA DENGAN PERKEMBANGAN SOSIAL DI INDONESIA
Authors: Bahar Muchlis
Published: January 2023

The purpose of this study is to analyze salafiyah da'wah as a dialectic of religious communities with social developments in Indonesia. The research method used in this study is a qualitative method with a descriptive approach. The type of data used in this research is secondary data. This research begins by analyzing the development of various Salafi groups, then analyzing the da'wah methods and the ulama that are used as references, then various criticisms put forward for this group. Based on the results of the analysis and discussion, it can be concluded that the Da'wah of the Salafiyah movement prioritizes informal institutions in building a base. The essence of this movement is the spirit to purify Islamic teachings from cultural understandings that are destructive to Islam itself, which in many ways intersects with certain groups who disagree. In its development in Indonesia, this movement is not repressive towards the government and tends to prioritize various discourses on worship and Fiqh, but attracts many young people because they use social media a lot as a means of Da'wah for the Salafiyah group.
АДАПТАЦІЯ МОДЕЛІ ВІДЦЕНТРОВОЇ ФОРСУНКИ ДЛЯ РОЗРАХУНКОВО-ЕКСПЕРИМЕНТАЛЬНОГО ДОСЛІДЖЕННЯ РОБОЧОГО ПРОЦЕСУ В ОСНОВНІЙ КАМЕРІ ЗГОРЯННЯ ТРДДФ
Authors: Шульгін Артем , Самулєєв Володимир , Чемерис Євгеній , Трегуб Олександр
Published: January 2023

У статті сформульовано припущення щодо можливості використання адаптованої моделі двосоплової відцентрової форсунки при комплексному розрахунково-експериментальному дослідженні робочого процесу в жаровій трубі основної камери згоряння турбореактивних двохконтурних двигунів з форсажною камерою згоряння (ТРДДФ). Проведено чисельне моделювання впорскування рідини в повітряне середовище на основі усереднених за Рейнольдсом рівнянь Нав’є-Стокса, що описують течію двофазової нестисливої рідини. На основі порівняння результатів візуалізації чисельного моделювання з результатами фізичного експерименту з проливання форсунки ТРДДФ обґрунтовано можливість використання сформованого припущення.
ДОСЛІДЖЕННЯ ВПЛИВУ НА АЕРОДИНАМІКУ КОМПОНОВКИ РОЗТАШУВАННЯ ЗОВНІШНІХ ПІДВІСОК ОЗБРОЄННЯ ЛІТАЛЬНОГО АПАРАТУ
Authors: Коритько Олександр , Підчибій Леонід , Почерняєва Світлана
Published: January 2023

В статті пропонується шлях вирішення проблеми скорочення потрібної кількості випробувальних польотів та часу на їх проведення при виконанні досліджень аеродинамічних характеристик з наявністю великої кількості варіантів зовнішніх підвісок озброєння.

Пропонується застосовування для цього теоретичних чисельних методів аеродинаміки. На прикладі дослідження за допомогою добре відомого методу дискретних вихорів виконано розрахунки компоновки, яка складалася з крила, схожого на крило літака Су-25, і ракет класу “повітря-земля” типу Х-58Э. Ракети розміщувались симетрично відносно осі  крила носія, але на різних точках підвіски вздовж розмаху.

Дослідження показали достатньо цікаві результати. Наприклад, наявність ракет та їх розміщення на різних точках майже не впливає на величину відносної координати фокусу компоновки за кутом атаки.

Присутність ракет безумовно впливає на аеродинамічні характеристики компоновки, але цей вплив виявився не дуже  значним. Останнє можна пояснити досконалими власними аеродинамічними характеристиками добре несучого крила. Воно має помірну стрілоподібність та достатньо велике подовження.

Наявність ракет та їх переміщення до кінцівок крила майже не змінює величини індуктивного лобового опору. Деяке збільшення несучих властивостей компоновки компенсується збільшенням величини її підсмоктуючої сили на передніх крайках несучих поверхонь.
Boron and orthopedic implants: A review of the literature
Authors: Özkul Emin , Tekin Recep , Ulus Sait Anıl , Atiç Ramazan , Yiğit Şeyhmus , Akar Mehmet Sait , Durgut Fatih , Dönmez Sait
Published: January 2023

A material created to interact with biological systems to enhance, treat or modify a tissue, organ, or body function is called a biomaterial. Sutures, dental fillings, needles, catheters, bone plates, and orthopedic implants are the most commonly used medical biomaterials. With the increasing use of orthopedic implants worldwide, there remains significant interest in developing new technologies to improve the effective clinical performance of contemporary treatment modalities and devices. Biomaterials used in orthopedics often require revision due to problems such as wear, corrosion, and infection. These revisions have become a significant burden for the patient and the healthcare system. Boron, with its unique properties, is an element that has the potential to overcome these problems. Therefore, in recent years, the importance of boron elements in the health field as well as in the industrial field has been noticed, making the use of boron in medicine very popular
ATIK YÖNETİMİ VE SIFIR ATIK PROJESİNİN DEĞERLENDİRİLMESİ: İSTANBUL İLİ ÖRNEĞİ
Authors: BULUT Arzu , ŞENGÜL Halil
Published: January 2023

Bu çalışmanın amacı, İstanbul'da ikamet eden bireylerin atık yönetimi ve sıfır atık projesine yönelik algı düzeylerini incelemektedir. Bu çalışma kesitsel ve tanımlayıcı tasarımda bir araştırmadır. Araştırmanın evrenini, İstanbul'da ikamet eden 18 yaş ve üzeri bireyler olup, örneklem büyüklüğü, yaşları 18 ile 66 arasında değişen 161 erkek ve 229 kadın olmak üzere 384 kişiden oluşmaktadır. Anketler, kolayda örnekleme yöntemine göre seçilen katılımcılara Google formlar ve yüz yüze görüşme yoluyla ulaştırılmıştır. Tüm istatistiksel analizlerde IBM SPSS paket programı kullanılmıştır. Medeni durum ile Atık Yönetimi ve Sıfır Atık Projesi Ölçeği toplam (p