bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Positive Deviance Approach on Promotion of Safe Disposal of Child’s Feces in Rural Tamil Nadu: A Community-Based Quasi-Experimental Study
Authors: Nancy S. , Gayathri S , Rahman K. Mujibur , Govindarajan P. K.
Published: January 2024

Introduction:

Safe disposal of feces is ensured when it is deposited into a toilet, whereas unsafe disposal of child’s feces plays a crucial role in disease transmission and environmental pollution. These areas are overlooked by many sanitation promotion interventions.

Objective:

To determine the effect of positive deviance (PD) approach on safe disposal of child’s feces among households who owned a toilet.

Materials and Methods:

A community-based quasi-experimental study was conducted in the four field practice villages of the Urban Health Training Center, Villupuram, for 18 months. Households who owned a toilet and had a child less than 5 years old were included. After IEC clearance, information was collected from a representative sample of 100 households before intervention and another 100 households after intervention. PD approach was applied for 6 months to promote safe disposal practices in the study villages. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) software (version 24). The Chi-square test was used to determine the significance of difference between baseline and endline data. The effect size was calculated to estimate the magnitude of difference between baseline and endline data.

Results:

Before intervention, only 3% of households disposed the feces into a toilet, while after intervention, almost 38% of households disposed in the toilet (χ2 = 37.39; df = 1; P = 0.001). The effect size (Cramer’s V) was found to be 0.43.

Conclusion:

PD approach demonstrated considerable improvements in safe disposal of child’s feces in rural settings. Further, to sustain the behavior change, frequent reinforcement of key messages at frequent intervals needs to be emphasized.
Organizing Health Camp: Opportunities for Building Public Health Skills
Authors: Dora Susmita , Panda Prem S. , Taywade Manish , Patro Binod K.
Published: January 2024

Health camps are one of the commonly performed activities by different organizations with different intentions. The purpose ranges from reaching out to unreached populations to increasing client base and thus increasing revenue generation. A multi-speciality health camp was organised at Rural Health & Training Centre (RHTC), Mendhasala, Khurdha. We describe the camp profile and utilization of different specialties in this study. The camp was attended by mostly adults and elderly (90.3%) and inhabitants of the same village (80.5%). General medicine (30.6%) and orthopedics (31.9%) were the two specialties most consulted at the said camp. The success of a health camp is described by the number of attendees, which looks only at resource utilization. We have documented the lessons learned from organizing a health camp from a public health learning point of view. A 10-point checklist is recommended for the successful organization of a health camp.
Assessment of Quality of Life among Terminally Ill Cancer Patients Receiving Palliative Care at Hospice Centre, Ahmedabad City, India
Authors: Geriya Disha , Dave Viral
Published: January 2024

Background:

Cancer has been the leading cause of death worldwide, and palliative care is an approach that improves the quality of life (QoL) of patients and their families facing the problem associated with life-threatening illness. Hospice care helps patients and their family to cope with the change from treating the cancer to living life as fully as possible through their final days. This study aimed to (1) assess the sociodemographic and clinical profile of terminally ill cancer patients, (2) assess the QoL among terminally ill cancer patients receiving palliative care, and (3) study various determinants affecting their QoL.

Material and Methods:

A cross-sectional study was conducted among terminally ill cancer patients receiving palliative care at the Hospice Centre, Community Oncology Centre, Ahmedabad. Based on previous years’ admission data, a sample size of 360 was taken. Patients who are seriously ill up to the extent that they were unable to respond and had a previous positive history of psychiatric illness before the diagnosis of cancer were excluded. Institutional ethical committee (IEC) permission was obtained before the study. Statistical analysis was performed using the Chi-square test in Statistical Package for the Social Sciences (SPSS) software.

Results:

The mean age of participants was 48.1 ± 13.0 years. The gender distribution of participants was males and females (226 (62.8%) and 134 (37.2%)), respectively. On studying, the involvement of various anatomical sites as “primary site of cancer” revealed that head and neck carcinoma had the highest (63.3%) involvement and hematological cancer had the lowest (0.6%) involvement. Of total, 62% of participants had “below-average QoL,” followed by 34.9% of participants having “significantly poor QoL.” There was a significant association between different age groups, time lag in cancer diagnosis, and treatment initiation and QoL.

Conclusion:

Spearman’s rank correlations between the majority of factors fell in “low partially positive” category except for the physical well-being (factor 2) and psychosocial well-being (factor 3) with optimism and belief (factor 7), where they were in “low partially negative” category.
Household Transmission of SARS-CoV-2 in the Third Wave of the Pandemic with Special Reference to Clinico-epidemiological Characteristics
Authors: Joshi Suvarna A. , Shah Pooja G. , Gajbhiye Mayuri R. , Pillai Praveena , Dudhate Sonali N. , Karyakarte Rajesh P.
Published: January 2024

Background:

Coronavirus disease 2019 (COVID-19) pandemic began in India in 2020. Despite successful vaccination, cases again started increasing from mid-December 2021. Therefore, this study was undertaken to find out the clinico-epidemiological characteristics and effectiveness of vaccination in the household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in and around Pune.

Material and Methods:

All samples received from December 15, 2021, till February 15, 2022, were included in the study. Samples received in viral transport medium (VTM) were extracted by the MagMAX RNA Extraction Kit, and reverse transcriptase–polymerase chain reaction (RT–PCR) was performed by the CoviPath Kit as per kit guidelines. Values of nucleocapsid (N) gene and open reading frame (ORF) less than 37 were considered positive. Clinico-epidemiological data were analyzed from the sample referral form (SRF).

Results:

A total of 712 of 1032 household contacts of 271 families were positive. When geographical areas were compared, it was found that rural areas were affected more (63.76%) as compared to urban areas (36.24%). Males were more affected than females. The most commonly affected age group was 41–50 years (26.54%). Small families were found to have more household transmission. Mild symptoms were present in 97.89%. Among 271 infected individuals, seven were admitted to hospital, of which one patient died due to pneumonia. Two doses of vaccination were completed in 93.95%, and 3.79% had taken booster dose.

Conclusions:

Data from this study showed that a high rate of transmission was observed in household contact despite two doses of vaccination. However, these vaccinated individuals had mild symptoms, maybe due to the effect of vaccination and infecting variant omicron.
Assessment of progression-free survival and overall survival in patients of glioblastoma post-radiation therapy
Authors: Singhal Saloni , Kumar Amresh , Rajput Neha Singh , Lodi Ashar Iqbal , Bhandari Virendra
Published: January 2024

Introduction:

Glioblastoma (GBM) is the most aggressive and heterogeneous subtype of glioma, at the tissue, cellular and molecular level, and has the highest short-term mortality rate. The average 5-year survival rate for GBM is 7.2%.

Materials and Methods:

This was a single institute retrospective study. All patients have treatment and follow-up data available in their medical charts, which were being extracted for this study, and being evaluated and their survival is calculated.

Results:

We found maximum survival of 132 months and minimum survival of 1 month with a median survival of 9 months and 2 and 5-year survival of 25.8% and 16.13%, respectively, post radiation therapy.

Conclusion:

Survival in central nervous system tumor has improved widely with adjuvant concurrent chemoradiation postoperatively.
Upper Limb Vascular Traumas with Vascular Exposure: Difficulties of Reconstruction in an Isolated Cardiovascular Surgical Environment
Authors: Kirioua-Kamenan Yoboua Aimé , Yeo Ibrahim Junior , Degre Jean Calaire , Asseke Assoumou Lucien , Katché Koutoua Eric , Kassi Marc Hervé , Souaga Kouassi Antonin
Published: January 2024

Introduction and Objective:

Advocate for the knowledge and development of intrahospital therapeutic management of vascular trauma with vascular exposure, in our working conditions.

Materials and Methods:

This was a descriptive retrospective study which covered the period from January 2015 to June 2022. It was carried out from the medical records of patients operated on for vascular trauma with exposure of the vessels, in the Cardiovascular Surgery Department at the Abidjan Heart Institute. The following data were studied: epidemiological data, anatomo-clinical characteristics, and therapeutic data.

Results:

Nine medical records of eight male and one female patient were collected. The average age of the patients was 36 years. Elementary vascular lesions were as follows: complete section of the brachial artery and vein (n = 3), loss of substance of the brachial artery (n = 2), contusion of the brachial artery (n = 1), lateral wound of the ulnar artery (n = 2), and complete section of the radial artery (n = 1). Revascularization consisted in a brachio-brachial arterial bypass using a great saphenous vein graft (n = 3), end-to-end, respectively, arterial and venous anastomosis (n = 3), direct suture of the ulnar artery (n = 2), and in a radio-radial end-to-end arterial anastomosis (n = 1). The covering flaps used were the biceps brachii brachial muscle pedicled flap (n = 6) and the pedicled fasciocutaneous inguinal flap of McGregor (n = 3). The immediate and short-term postoperative follow-up was simple in all patients with scars of good trophicity.

Conclusion:

The surgical treatment requires skills in plastic surgery for the cardiovascular surgeon or the joint participation, in an emergency, of the cardiovascular surgeon and the plastic surgeon or, if necessary, the management of the patient in two stages. This last therapeutic modality generates additional morbidities and financial cost for the patient.
Giant Right Common Iliac Artery Aneurysm with Right Common Iliac Vein Fistula, Masquerading as Deep-Vein Thrombosis
Authors: Unnikrishnan Madathipat , Rahul S M , Harinath R , Kumar S P Shenoj , Mohan M Arun , Alexander Renny
Published: January 2024

Iliac artery aneurysm is rarely known to rupture into iliac vein, leading to features of aneurysm and in particular, right ventricular volume overload, and pulmonary artery hypertension, due to the extracardiac left to right shunt. Herein, we report the case of a 67-year-old gentleman who presented with massively swollen right lower limb, leading to pain and inability to walk without support for 1 month. He was diagnosed to have and treatment for deep vein thrombosis with Vitamin K antagonist for 2 years. Contrast computed tomography angiogram of the abdomen revealed giant right iliac artery aneurysm above its bifurcation with iliac vein fistula. He underwent open repair of aneurysm and transaneurysmal suture closure of the iliac fistula. However, for transient renal dysfunction and reexploration for pelvic hematoma, his recovery, including normalized right lower limb, was smooth.
Our Experience in Managing Carotid Body Tumors in Tertiary Care Center
Authors: Kotavenuka Vinay Kumar , Vishnumolakala Vijay Kumar , Desai Sanjay C , Ramswamy Chandrashekar Anagavalli , Manchikanti Sriram , Gowda Suhas
Published: January 2024

Introduction:

Carotid body tumors (CBTs), also known as paragangliomas or chemodectomas, are rare neuroendocrine neoplasms that arise near the carotid bifurcation within glomus cells derived from the embryonic neural crest. The reported incidence of CBTs is 1–2 cases per 1 lakh cases. Surgery is the mainstay of treatment.

Objectives:

The objective of this study was to report our experience and describe the presentation, surgical approach, postoperative complications, and outcomes of surgical treatment.

Materials and Methods:

It is a single-institution experience where a retrospective analysis of 6 cases with CBTs of patients who were candidates for surgery from June 2018 to June 2021 with a mean follow-up period of 24 months was done.

Results:

The mean age was 37 years, with a female predominance of 66%. The mean size of the tumor was 4.4 ± 1 cm. Four (66%) cases were presented with pain and pulsating neck swelling, and 2 (33%) cases were incidentally detected. All the cases were unilateral tumors. Neck ultrasound was done in all cases as a primary investigation. Magnetic resonance imaging was performed in 5 (87.5%) cases, which revealed tumors having near circumferentially encasing the internal carotid artery (ICA). No cases were malignant. All cases were surgically approached through transcervical vertical incision. Four cases (66%) and 2 (33%) cases were classified as Shamblin’s type II and III, respectively. Two (33%) cases needed special maneuvers such as division of the posterior belly of digastric and nasal intubation for the extra length of ICA. No major complications occurred. One patient (16.6%), as the tumor could not be dissected from the adventitia of ICA so, had to resect it, and primary end-to-end anastomosis was done. External carotid artery ligation was performed in 1 (16.6%) case. Minor postoperative complications such as hoarseness of voice occurred in 2 (33%) patients. No operative mortality occurred.

Conclusion:

We found a predominance of women and pain as the most common presenting complaint. Resection of CBTs by surgeons with experience in vascular reconstruction is recommended. Early surgical management is recommended to avoid neurological deficit or vascular reconstruction due to a Shamblin’s class III tumor. Preferred approach was caudo–cranial during dissection. Cranial nerve injury continues to be the most common complication.
Determinants of delirium in elderly in-patients in a general ward setting in a teaching hospital: A case control study
Authors: Geetha Jitha , Babu Haritha , George Christina
Published: January 2024

Background:

There is a dearth of research on risk factors of delirium among elderly inpatients in nonintensive low resource settings.

Aim:

To determine the risk factors of delirium in elderly inpatients in a nonintensive care unit setting.

Materials and Methods:

Sixty two elderly patients with delirium (cases) and 62 patients without delirium (controls) were administered a semi-structured proforma with socio-demographic variables and putative predisposing and precipitating risk factors and the Vellore screening instrument for dementia.

Results:

On univariate analysis, factors such as past cognitive impairment, history of nocturnal confusion and delirium, diminished daily living activities, severe medical illness, history of psychiatric illness, presence of dementia, infection, fever above 1000F, abnormal electrolytes abnormal RFT, leukocytes in urine, hypoxia, anticholinergics and benzodiazepines, emergency admission, use of physical restraints, bladder catheterization, more than routine investigations, intensive care unit admission, surgery, and duration of hospital stay more than 10 days were found to be significantly associated with delirium. On multivariate analysis with binary logistic regression, bladder catheterization (odds ratio [OR] = 13.85; confidence interval [CI] = 1.44-133.14), abnormal electrolytes (OR = 5.12; CI = 1.11-23.69), and hypoxia (OR = 75.52; CI = 4.64-1.134E3) were detected to be independently associated with delirium.

Conclusion:

Acute modifiable rather than long-term factors were risk factors for delirium among the elderly. An awareness of modifiable risk factors has the potential of developing targeted interventions for the early mitigation of delirium.
Uncertainty evaluation of non-invasive multi-parameter detector measurements in quality assurance of diagnostic radiology
Authors: Senthilkumar M , Senthil Kumar C , Parmar R. U , Velmurugan J
Published: January 2024

Objective:

To optimize the patient dose and image quality through quality assurance (QA) of diagnostic x-ray equipment and to ensure compliance with international and national standards in x-ray specification parameters, the use of contactless and quick non-invasive instruments has gained importance. Considering the importance of equipment qualification and the intervention level for equipment management, it is vital to account for uncertainties in the measurement of parameters in diagnostic radiology. However, the limits and measurement uncertainties associated with the parameter measurement are not well established and many technical and scientific literature provide different tolerance values, either as absolute or in terms of percentage.

Methods and Materials:

In this paper, the authors analyze non-invasive multi-parameter detector measurements with the aim to (i) improve the accuracy in measurement of x-ray parameters (kilovoltage, dose, and exposure time); (ii) estimate the uncertainty associated with such measurements; (iii) analyze the tolerance values prescribed by various professional and regulatory bodies and propose an improvised method of reporting the parameters. The approach adopted in this paper takes into account the uncertainties associated with traditional instruments and the subjectivity in the measurements.

Results:

Estimated uncertainty for kV measurements in the range between 1.45 kV at 40 kV measurements and 4.88 kV at 150 kV measurements. The MU associated with the dose measurement is estimated to be 6.2% at 110 kVp, 100 mA, and 500 msec. Maximum MU estimated at 10 msec exposure time is 4.5% and with MU of 5% deviation added to 9.5%.

Conclusions:

The current practice of reporting the measured mean values deviation without considering the inherent measurement uncertainty may not be a correct quantification procedure in QA. This is evident from the case study that 3% addition to the measured kV, 6.2% addition in the measured dose, and 4.5% to the measured time accounts for measurement uncertainty.
Assessment of the prevalence of types of head and neck cancer in a tertiary cancer center at Madurai, Tamil Nadu: A cross-sectional study
Authors: SathiyaPriya S , Shavi Girish R. , Sanga Ranganath , Shankar S , Gunasekaran Lalithambigai , Rahila C , Santhakumari S
Published: January 2024

Aim:

The aim of the study was to assess the prevalence of types of head and neck cancer in Madurai, Tamil Nadu.

Objectives:

The objectives of the study were to assess the prevalence of types of head and neck cancer in Madurai, Tamil Nadu using a questionnaire.

Materials and Methods:

A descriptive cross-sectional study was carried out for two months among 300 head and neck cancer patients at a tertiary cancer center in Madurai. A convenience sampling technique was used. The data were collected using a pretested, self-structured questionnaire. The data were analyzed using the Statistical Package for the Social Sciences (SPSS) version 20.0 software.

Results:

Of 300 head and neck cancer patients, the mean age of the patients was about 51.04 ± 16.49 years. The majority of the patients were male (80%), employed (85%), and literate (65%). Among the head and neck cancer patients, 65% were tobacco users and 42.4% were alcohol consumers. Squamous cell carcinoma was the most common type of head and neck cancer, and 79.7% were diagnosed at an advanced stage of said cancer, such as stages III and IV.

Conclusion:

Lack of knowledge and awareness is a major cause of increasing prevalence of head and neck cancer in our country. It is most important to increase the knowledge and awareness of early symptom recognition and its seriousness among the general population.
Stereotactic radiosurgery in India: A nationwide survey of technology and quality assurance practices
Authors: Patwe Parimal T. , Deshpande Sudesh , Chaudhari Suresh , Mahajan Gajanan R.
Published: January 2024

Purpose:

India is rapidly adopting advanced treatments like Stereotactic Radiosurgery (SRS). However, there is a paucity of data on SRS practice. The aim of study is to assess the current status of technology and practices of machine quality assurance (QA) and patient specific quality assurance for SRS in India.

Materials and Methods:

A survey questionnaire was designed using Google Forms and sent to chief/senior medical physicists across 220 radiotherapy centers in India on July 15, 2022. It contained questions on infrastructure availability, treatment planning, and QA.

Results:

SRS was found to be extensively used for the treatment of brain metastases (99.3%), followed by meningioma (50.3%), acoustic neuroma (45.5%), and pituitary tumours (33.1%). The most commonly used photon energy and treatment technique were 6MV FFF and VMAT, respectively. A prescription isodose line ranging from 70% to 100% was selected by linac users. Most linac institutes verify pretreatment doses. There was a lack of uniformity in the analysis metrics such as Low Dose Threshold, Dose Difference, and Distance to Agreement. A survey revealed that the variety of SRS QA programs being followed at Indian radiotherapy centers.

Conclusion:

This is the first study to report the physics practice of SRS in India. The survey shows a need to carry out a postal dose audit for small static photon fields in India.
MRI assessment of ovarian masses and correlating with CA-125
Authors: Ranganath Amrutha , Sakalecha Anil K. , Darshan A. V. , Vineela E.
Published: January 2024

Background:

The combined use of appropriate imaging modalities and serum biomarkers like serum Carcinoembryonic Antigen-125 (CA-125) helps plan treatment strategies and reduce overall mortality.

Aims and Objectives:

To assess ovarian masses on Magnetic Resonance Imaging (MRI) and correlate them with serum CA-125 values. To derive a new serum CA-125 cut-off value for differentiating benign from malignant ovarian masses.

Materials and Methods:

This cross-sectional study was conducted from August 2020 to January 2021 on patients with suspected pelvic masses referred to the department of radio-diagnosis and meeting inclusion and exclusion criteria. Serum CA-125 values and imaging features on MRI were recorded.

Results:

A total of 37 ovarian masses were included in the study, of which 14 were malignant and 23 were benign. The mean CA-125 values among benign [35.95 ± 25.42 (mean ± SD) IU/ml] and malignant ovarian masses [444.82 ± 232.9 (mean ± SD) IU/ml] were statistically significant (<0.001). Using the reference serum CA-125 value of 35 IU/ml, specificity and accuracy were 61% and 75.68%. A cut-off value of 80.5 IU/ml recorded specificity and accuracy of 95.7% and 94.59%, respectively, with a sensitivity of 92.86% in differentiating benign from malignant ovarian masses.

Conclusion:

The serum CA-125 cut-off value of 80.5 IU/ml is a sensitive and specific serum biomarker for ovarian malignancies. A combined approach of MR imaging and serum CA-125 correlation can be used in characterizing ovarian malignancies in routine clinical practice.
Role of CYFRA 21-1 and CEA as prognostic and predictive markers in locally advanced and metastatic gastric carcinoma
Authors: Gopal Vishnu , Nisha Yadav , Ganesan Prasanth , Kayal Smita , Bobby Zachariah , Adithan Subathra , Penumadu Prasanth , Ramakrishnalay Vishnu P. , Bandlamudi Bhanu P. , Bahttacharjee Arnab , Dahagama Sindhu , Dubashi Biswajit
Published: January 2024

Purpose:

Tumor-associated serum markers have demonstrated predictive and prognostic value in patients being treated for malignancies. However, the clinical importance of tumor markers in gastric cancers (GC) is poorly standardized.

Objectives:

The objective is to assess the clinical utility of cytokeratin-19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA) as serum tumor markers in advanced GC.

Methods:

In this prospective study, CYFRA 21-1 and CEA levels were measured at baseline and after three cycles of chemotherapy in patients with advanced GC. The association of tumor marker levels with prognosis and decline of tumor markers with radiological overall response rates (ORR) and survival were analyzed.

Results:

In the 105 patients, the proportion of patients with elevated baseline CYFRA 21-1 and CEA levels was 55% (N = 58) and 37% (N = 39) based on predefined cutoffs. Response assessment was done for 61 patients who received a minimum of three cycles of chemotherapy. A 15% and 13% reduction of serum levels from baseline for CYFRA 21-1 and CEA were selected for defining “CYFRA 21-1 response” and “CEA-response,” respectively. Both responses were significant predictors of radiological ORR. The median overall survival (OS) was 9.6 months in the entire cohort and 13 months for patients who received at least three cycles of chemotherapy. In multivariate analysis, baseline CEA levels and ECOG status were significant predictors of OS. In a subset analysis of patients receiving palliative chemotherapy, any of the tumor marker responses predicted improved 1-year OS.

Conclusion:

In advanced GC, CYFRA 21-1 and CEA decline from baseline appeared to be reliable surrogate markers of chemotherapy efficacy and improved survival.
Role of fecal microbiota transplant in management of hepatic encephalopathy: Current trends and future directions
Authors: Shah Yash R , Ali Hassam , Tiwari Angad , Guevara-Lazo David , Nombera-Aznaran Natalia , Pinnam Bhanu Siva Mohan , Gangwani Manesh Kumar , Gopakumar Harishankar , Sohail Amir H , Kanumilli SriLakshmiDevi , Calderon-Martinez Ernesto , Krishnamoorthy Geetha , Thakral Nimish , Dahiya Dushyant Singh
Published: January 2024

Fecal microbiota transplantation (FMT) offers a potential treatment avenue for hepatic encephalopathy (HE) by leveraging beneficial bacterial displacement to restore a balanced gut microbiome. The prevalence of HE varies with liver disease severity and comorbidities. HE pathogenesis involves ammonia toxicity, gut-brain communication disruption, and inflammation. FMT aims to restore gut microbiota balance, addressing these factors. FMT's efficacy has been explored in various conditions, including HE. Studies suggest that FMT can modulate gut microbiota, reduce ammonia levels, and alleviate inflammation. FMT has shown promise in alcohol-associated, hepatitis B and C-associated, and non-alcoholic fatty liver disease. Benefits include improved liver function, cognitive function, and the slowing of disease progression. However, larger, controlled studies are needed to validate its effectiveness in these contexts. Studies have shown cognitive improvements through FMT, with potential benefits in cirrhotic patients. Notably, trials have demonstrated reduced serious adverse events and cognitive enhancements in FMT arms compared to the standard of care. Although evidence is promising, challenges remain: Limited patient numbers, varied dosages, administration routes, and donor profiles. Further large-scale, controlled trials are essential to establish standardized guidelines and ensure FMT's clinical applications and efficacy. While FMT holds potential for HE management, ongoing research is needed to address these challenges, optimize protocols, and expand its availability as a therapeutic option for diverse hepatic conditions.
Metabolic disease and the liver: A review
Authors: Vargas Márcia , Cardoso Toniasso Sheila de Castro , Riedel Patricia G , Baldin Camila Pereira , dos Reis Francielle Lopes , Pereira Robson Martins , Brum Maria Carlota Borba , Joveleviths Dvora , Alvares-da-Silva Mario Reis
Published: January 2024

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common liver disease worldwide, with an estimated prevalence of 31% in Latin America. The presence of metabolic comorbidities coexisting with liver disease varies substantially among populations. It is acknowledged that obesity is boosting the type 2 diabetes mellitus “epidemic,” and both conditions are significant contributors to the increasing number of patients with MASLD. Non-alcoholic steatohepatitis represents a condition of chronic liver inflammation and is considered the most severe form of MASLD. MASLD diagnosis is based on the presence of steatosis, noninvasive scores and altered liver tests. Noninvasive scores of liver fibrosis, such as serum biomarkers, which should be used in primary care to rule out advanced fibrosis, are simple, inexpensive, and widely available. Currently, guidelines from international hepatology societies recommend using noninvasive strategies to simplify case finding and management of high-risk patients with MASLD in clinical practice. Unfortunately, there is no definite pharmacological treatment for the condition. Creating public health policies to treat patients with risk factors for MASLD prevention is essential.
AYURVEDIC MANAGEMENT OF GRIVASTAMBHA (SPONDYLITIS): A CASE REPORT
Authors: Mote Samruddhi , Rohani Sachin , Joshi Vinayak , Udmale Mangesh
Published: January 2024

Grivastambha is a painful disorder mainly associated with vitiation of Vata & Vyana vayu. The vitiated Vata gets lodged in neck region resulting muscular pain in neck area. It is a chronic degenerative condition mainly affects cervical spine, vertebral bodies, facet joints & longitudinal ligaments. The quality of life of a diseased person deteriorates and it is becoming difficult to conduct normal daily routine. The disease mainly occurs in male during the period of early ageing. Grivastambha is considered under different types of Nanatmaja Vata Vyadhi. The localization of aggravated Vata in Manya Samshrita Nadi leads to symptoms of Stambha and Shoo-la. In this article 53-year female patient diagnosed with Grivastambha treated with Ayurvedic Management.
A CASE STUDY- AN AYURVEDA APPROACH ON POLYCYSTIC OVARIAN SYNDROME
Authors: Nandi Arpita , Tahira Taiyeba , Ghosh Sukumar
Published: January 2024

A woman is the best and most precious creation of God. Women’s bodies undergo significant changes through-out their lives, leading to differences in health concerns for varying age groups. The reproductive cycle signifi-cantly affects in every stage of a woman’s life during the transition from a girl to a woman and a woman to a mother. PCOS is the most challenging lifestyle disorder that can affect women’s Multiple system and require a comprehensive perspective on health care for effective treatment. Metabolic derangement and associated com-plications include insulin resistance and diabetes, hyperlipidemia, fatty liver, hypertension, and sleep apnoea. Reproductive complications include oligomenorrhoea /amenorrhea, sub-fertility, endometrial hyperplasia, and cancer. Associate psychological concerns include depression and disordered eating. Additionally, cosmetic is-sues are hirsutism, androgenic alopecia, and acne. This particular feminine disorder is not described word for word in Ayurveda. Ayurveda literature is under the broad heading of Yoni vyapad, Artava dustya, and Artava kshaya. Analyzing the signs and symptoms of diseases, it can be assumed that vitiated Kapha causes Sroto-rodha (blockage of channels), resulting in Vata vaigunya. Agneya property of pitta depleted. Here is a case re-port of 25 a 25-year-old female patient who presented with irregular menstruation, rapid weight gain, and de-pression. On Ultrasonography, she has detected a bilateral polycystic ovary. Depending upon the clinical fea-tures, the patient was given Aampachan. Vatanuloman, Kaphavata hara, Medohara, and Artavajanana proper-ties of medicines and yoga. After almost three and half months of internal medicine, symptoms reduced marked-ly, and menstruation was normal.
THE REALIZATION OF SYSTEMATIC CADASTRE WORKS IN THE PERSPECTIVE OF THE SUSTAINABLE DEVELOPMENT OF THE VINEYARD AND FRUIT-GROWING SECTOR IN ROMANIA
Authors: Hutanu Cristian , RADU Oprea
Published: January 2024

In order to develop the vineyard and orchard sector in Romania from a sustainable point of view, the European Union primarily finances plantations with native varieties. To be able to talk about sustainable development and environmental protection, GIS systems should be structured by fields of activity and become an interface between man and nature. The integration of these projects within the systematic cadastre work would have the effect of obtaining a better reassessment of the agricultural potential of the area. Thus, the "Vasile Adamachi" didactic farm of the Iasi University of Life Sciences has reconfigured the cadastral plots, currently occupying a total area of 16.1 ha with vines and 12.2 ha with fruit trees. This project to modernise the vineyard/fruit-growing plantations was realised from the rehabilitation funds of the European Union, through the Payments and Intervention Agency for Agriculture. The creation by the Cadastre and Real Estate Publicity Agency of an integrated cadastre and land book system, as a "multipurpose" type system within the National Cadastre and Land Book Program, would help the Payments and Intervention Agency for Agriculture to identify agricultural real estate, which includes vineyards/fruit trees, and would encourage the owners of such plantations to access projects from the European Union funds for the modernisation, maintenance in good condition or expansion of vineyard and fruit-growing. Also, the technical-legal situation of the existing real estate at the administrative-territorial unit level could be obtained in real time.
Respon Konsumen Terhadap Produk Yotta Rasa Brown Sugar Fresh Milk di Kabupaten Maros
Authors: Janna Miftahul , Sadat Mohammad Anwar , Arifin Arifin
Published: January 2024

The purpose of this study is to identify the variables that influence Maros Regency consumers' reactions to Yotta Beverage products. Direct observation and questionnaire data collection were used in this study. The study took place over a three-month period from March to May, and was conducted in Turikale Sub-district, Maros Regency. To determine customer reactions to Brown Sugar Fresh Milk flavored Yotta products in Turikale Sub-district, Maros Regency, quantitative data was used. Based on the research findings, price and taste are the main determinants of Yotta Taste Brown Sugar Fresh Milk in Turikale District, Maros Regency.
Ciencias sociales cualitativas y confiabilidad de los referentes empíricos. Discusión epistemológica desde la fenomenología
Authors: Villalobos-Antúnez José Vicente , Guerrero-Lobo José Francisco , Martín-Fiorino Victor , Ramírez-Molina Reyner
Published: January 2024

El presente trabajo se interna en las discusiones acerca del significado del habla en la investigación cualitativa. Su propósito es participar del diálogo epistemológico mediante la incorporación de elementos del discurso en torno al dueto positivismo/pospositivismo. Articulando las cuestiones fundamentales acerca del habla como dimensión humana, se contrapone al significado objetivista y positivista reflejado en el trabajo de Gutiérrez y Arnal (2023). La idea es la de discutir las conclusiones que se exponen en dicho trabajo, en especial, la referida a la inexistencia de referentes empíricos en la investigación cualitativa, debido a la falta de objetivación en la relación observador-observado, por lo cual, debido a ello, genera falta de confianza en sus resultados. Se concluye que el positivismo en la investigación cualitativa no puede fundamentar los referentes empíricos relacionados con el diálogo que se entabla en la situación hermenéutica que se funda desde este paradigma de investigación cualitativo, especialmente desde la fenomenología, ámbito desde el cual surge esta situación hermenéutica.
La gamificación: impacto en el aula y autonomía de los estudiantes
Authors: Angeles Millones Rubén Dario
Published: January 2024

Con respecto a gamificación es un planteamiento educativo renovador para proponer asuntos vinculados con responsabilidad, motivación de los estudiantes y el logro académico en las distintas divisiones del aprendizaje. A partir de todo esto se deduce que la influencia de los juegos en el entorno educativo beneficia a los estudiantes al promover su participación activa, captar su atención, fomentar la autonomía, generar un espíritu competitivo y, sobre todo, lograr un buen desempeño académico. Por lo tanto, el propósito de esta investigación fue examinar los impactos observados en las motivaciones, el comportamiento y el rendimiento académico de los estudiantes universitarios. Con este fin, se pretende implementar las dinámicas características de los juegos en la educación superior, lo que permitirá un enfoque más adecuado para la investigación. Se utilizó un enfoque cuantitativo de investigación no experimental con el propósito de analizar los efectos de los juegos en las motivaciones, el comportamiento y el rendimiento académico de los estudiantes universitarios. Como resultado del estudio realizado, se constató que los juegos fomentan la autonomía, la motivación, el compromiso y la interacción social entre los estudiantes, lo que a su vez facilita el desarrollo y la comprensión de los temas abordados en cada desafío planteado.
Designing a Posyandu Scheduling System using a Data-base to Improve Patient Service [Perancangan Sistem Penjadwalan Posyandu Menggunakan Basis Data Untuk Meningkatkan Layanan Pasien]
Authors: Indra Astutik Ika Ratna , Imanudin Giri Fajar , Rosid Mochamad Alfan , Aji Sukma
Published: January 2024

Posyandu is a form of community-based health effort (UKBM) that is menaged and organized frm, by, and with the community in implementing healh development in order to empower the community and provide convenience to the obtaining basis heal/social service to accelerate the reduction in maternal and infant mortality. The Posyandu Scheduling System has a very important role to support the services of this public health program. Over time, problems arise regarding the system, in terms of preparing service schedules, still using the manual method, namely aliases, which are still handwritten to the recorder the Posyandu schedule in Kebonagung Village. This research is to design a website-based scheduling system that is useful for making it easier for cadres to disable and process Posyandu scheduling data in order to improve patient service. This system design uses the Hypertext Preprocessor (PHP) programming language, with a MySQL database, and uses Black Box testing to find out if the program is running as expected.
Implementasi Pembelajaran Berdiferensiasi untuk Mewujudkan Student’s Well Being pada Pembelajaran Biologi di SMA Negeri 1 Bangorejo
Authors: Nurmayasari Khilma Vita , Prafiasari Aulya Nanda
Published: January 2024

Penelitian ini bertujuan untuk menerapkan pembelajaran berdiferensiasi berdasarkan gaya belajar untuk mewujudkan student’s wellbeing pada pembelajaran Biologi materi Perubahan Lingkungan. Pembelajaran berdiferensiasi gaya belajar merupakan pembelajaran yang disesuaikan dengan minat dan karakteristik peserta didik serta gaya belajar mereka yaitu visual, audio, dan kinestetik yang berpusat pada peserta didik. Jenis penelitian yaitu kualitatif dengan menggunakan pendekatan deskriptif di kelas X.4 SMA Negeri 1 Bangorejo. Data mengenai gaya belajar peserta didik didapatkan melalui angket berupa google form. Hasil penelitian menunjukkan bahwa terdapat keragaman gaya belajar yang dimiliki oleh peserta didik dengan presentase tertinggi yaitu gaya belajar visual. Penerapan pembelajaran berbasis diferensiasi berdasarkan gaya belajar peserta didik dengan student’s well being memiliki peran yang signifikan terhadap hasil belajar peserta didik pada materi perubahan lingkungan karena peserta didik dapat mengekspresikan potensi yang dimiliki dengan memberikan pengalaman belajar yang lebih menyenangkan dan bermakna.
Penerapan Problem Based Learning Berbantuan Media Puzzle untuk Mewujudkan Karakter Profil Pelajar Pancasila pada Siswa Kelas X-4 SMAN Pakusari
Authors: Hariyanti Dewi , Utomo Agus Prasetyo , Fitriasih Widia
Published: January 2024

Dunia pendidikan saat ini mengarah pada proses pembelajaran yang berpusat pada siswa. Kurikulum Merdeka diciptakan sebagai kerangka kurikulum yang lebih fleksibel yang berfokus pada materi penting dan pengembangan bakat dan karakter siswa. Di kelas X-4, siswa kurang antusias dan tertarik dalam proses pembelajaran serta pemahaman terhadap materi biologi yang kurang sehingga Pengembangan Profil Pelajar Pancasila bertujuan untuk membantu siswa mencapai tingkat pemahaman, perilaku, dan karakter yang berlandaskan pada nilai-nilai pancasila. Salah satu cara untuk mengintegrasikan Profil Pelajar Pancasila ke dalam kegiatan pendidikan formal adalah dengan menggunakan model PBL dan untuk menarik perhatian siswa dibantu dengan media puzzle di dalam proses pembelajaran. Penelitian ini bertujuan untuk menganalisis penerapan model pembelajaran problem-based learning berbantuan media puzzle untuk mewujudkan karakter profil pancasila. Jenis penelitian ini adalah deskriptif kualitatif dengan subjek penelitian adalah peserta didik kelas X-4 di SMAN Pakusari. Teknik sampling dalam penelitian ini adalah non-probability sampling. Analisis data dalam penelitian ini adalah analisis naratif, dengan instrumen lembar observasi. Hasil penelitian menunjukkan bahwa penerapan model pembelajaran problem-based learning berbantuan media puzzle untuk mewujudkan karakter profil pancasila di kelas X-4 SMAN Pakusari dapat diterapkan dengan baik. Secara keseluruhan, aspek pada Profil Pelajar Pancasila terdapat kaitan dengan sintaks model pembelajaran PBL mulai dari pemberian apresiasi, berdiskusi, presentasi, hingga melakukan evaluasi. Kemudian, model pembelajaran Problem-Based Learning dapat mewujudkan 6 aspek atau dimensi Profil Pelajar Pancasila peserta didik kelas X-4 SMAN Pakusari.
Pembelajaran Teaching at the Right Level sebagai Implementasi Kurikulum Merdeka
Authors: Hadiawati Nurhalima Meirina , Prafitasari Aulya Nanda , Priantari Ika
Published: January 2024

Pembelajaran Teaching at the Right Level merupakan pendekatan pembelajaran yang berdasarkan kemampuan peserta didik. Artikel ini bertujuan untuk mereview pembelajaran Teaching at the Right Level dalam upaya implementasi kurikulum merdeka yang berorientasi pada kebutuhan peserta didik. Pengumpulan data pada penelitian ini menggunakan studi literatur dari artikel dan buku. Hasil penelitian konseptual mengungkapkan bahwa level kemampuan peserta didik merupakan acuan utama dalam merancang proses pembelajaran. Peserta didik dengan level kemampuan yang sama dikelompokkan dalam sebuah proses pembelajaran tanpa memperhatikan tingkat kelas dan usia. Selain itu, pendekatan ini dapat meningkatkan motivasi dan kemampuan literasi dasar peserta didik. Dapat disimpulkan bahwa pembelajaran Teaching at the Right Level memberikan kesempatan kepada siswa untuk mengembangkan kemampuannya secara efisien dan natural dengan guru sebagai mediator untuk menciptakan pendekatan yang dibutuhkan oleh peserta didik. Penerapan pembelajaran teaching at the right level mampu menciptakan pembelajaran yang berpusat pada peserta didik, dan menjadi lebih efektif sehingga dapat meningkatkan motivasi peserta.
Arsitektur Perangkat Lunak Berbasis Layanan Mikro pada Sistem Manajemen Informasi Kantin
Authors: Anwar Mukhammad Dayu , Kautsar Irwan A
Published: January 2024

Microservices menjadi salah satu cara untuk memaksimalkan performa dari service data yang akan digunakan untuk membuat sistem. Selain itu mudah untuk dikembangkan, karena setiap service nya sudah terstruktur dan terpisah untuk data yang akan dikonsumsi oleh developer lain. Kasus yang digunakan dalam penelitian ini adalah aplikasi E-Kantin, yang dimana sirkulasi data dari mitra, customer dan transaksi yang akan dikonsumsi oleh user harus berjalan dengan lancar. Dengan diimplementasikan nya microservices pada Aplikasi E-Kantin ini, maka sirkulasi data, kecepatan data yang dihasilkan akan sangat membantu untuk memaksimalkan setiap service yang dipakai. Hasil dari pengujian microservices yang telah dibuat, menunjukkan bahwa sirkulasi data dan service yang telah digunakan menjadi sangat efisien dan stabil pada saat banyaknya request atau akses dari user pemakainya. Dengan hasil tersebut, maka pengaruh dari microservices untuk sirkulasi data yang digunakan menjadi sangat efisien dan stabil.
Implementasi Fitur Notifikasi Whatsapp API pada Sistem Manajemen Tugas Akhir
Authors: Anjasmara Dimas Bayu , Rosid Mochamad Alfan , Eviyanti Ade
Published: January 2024

Simanta adalah aplikasi yang digunakan untuk melayani mahasiswa dalam pengelolaan Tugas Akhir mahasiswa. Diadakannya penelitian ini supaya aplikasi ini dapat melakukan pengiriman pesan notifikasi secara otomatis, pengiriman pesan secara otomatis menggunakan sistem Whatsapp API untuk menyampaikan pesan notifikasi atas aksi yang telah dilakukan dalam sistem. Dengan implementasi fitur notifikasi Whatsapp API pada SIMANTA didapatkan pengguna menjadi lebih mudah dalam menerima pemberitahuan terhadap aksi yang dilakukan pengguna dalam sistem SIMANTA. Metode Addie dipilih karena cocok bagi pengembangan sistem secara fleksibel dan efisien. Hasil penelitian membuat Sistem SIMANTA lebih praktis dan membuat pesan pemberitahuan lebih efektif untuk digunakan.
Perancangan Jaringan Internet RT/RW dengan Memanfaatkan Mikrotik dalam Memberikan Layanan Internet bagi Masyarakat
Authors: Setyawan Ricky Wahyu , Suprianto
Published: January 2024

Kebutuhan dari pengguna internet wireless menjadi tuntutan walaupun secara umum teknologi wireless masih belum bisa mengalahkan teknologi pendahulunya, dan perlu dipertimbangkan untuk kepuasan pengguna mengakses internet. Dalam penelitian ini penulis mengambil tema “Perancangan Jaringan Internet Rt/Rw Dengan Memanfaatkan Mikrotik Dalam Memberikan Layanan Internet Bagi Masyarakat”. Jaringan RT/RW Net sendiri adalah jaringan komputer warnet dalam ruang lingkup RT/RW melalui media kabel dan wireless sebagai sarana komunikasi masyarakat yang diburtuhkan saat ini. Melihat pada jaringan tersebut belum menerapkan sistem voucher mikrotik. Pada proyek akhir ini, penulis mengaplikasikan perancangan jaringan hotspot dengan sistem voucher menggunakan mikrotik pada RT/RW net sebagai sistemuntuk memudahkan client dalam pengkoneksian jaringan internet. Disamping itu juga sangat berguna untuk penyedia internet itu sendiri karena dengan sistem voucher dapat memudahkan dalam penyetingan ip client sehingga dapat meminimalisasikan waktu agar lebih efektif dan efisien untuk meningkatkan pelayanan kepada pengguna internet dan penyedia internet itu sendiri, sehingga diharapkan mampu memaksimalkan bisnis tersebut.