bluuebunny/crossref_metadata_2025 huggingface dataset:
Beetroot (Beta vulgaris) Extract: A Potential Therapeutic Agent for Modulating Post-Cholecystectomy Colonic Inflammation? An In Vivo Evidence Review
Authors: Mahmudin Ardian Ashadi  , Sigit Adi Prasetyo  , Yora Nintida
Published: February 2025

Background: Cholecystectomy, while a common and effective treatment for symptomatic gallstones, can induce alterations in bile flow and gut microbiota composition, potentially leading to colonic inflammation. Beetroot (Beta vulgaris) extract, rich in betalains, nitrates, and other bioactive compounds, has demonstrated anti-inflammatory and antioxidant properties in various models. This systematic review evaluates the in vivo evidence for the efficacy of beetroot extract in modulating colonic inflammation following cholecystectomy.
Methods: A systematic search of PubMed, Scopus, Web of Science, and Embase databases was conducted from January 2013 to May 2024, using keywords related to "beetroot," "Beta vulgaris," "cholecystectomy," "colon," "inflammation," and "in vivo." Studies investigating the effects of beetroot extract on colonic inflammation in animal models post-cholecystectomy were included. Data on inflammatory markers, histological changes, oxidative stress markers, and gut microbiota alterations were extracted.
Results: Seven in vivo studies met the inclusion criteria. Beetroot extract administration was associated with significant reductions in colonic levels of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) in five studies. Data showed an average reduction of TNF-α by 35% (p < 0.01), IL-6 by 28% (p < 0.05), and IL-1β by 42% (p < 0.001) across these five studies. Four studies reported improvements in histological scores of colonic inflammation, indicating reduced tissue damage. Three studies demonstrated a decrease in MPO activity, a marker of neutrophil infiltration, with data showing an average reduction of 25% (p < 0.05).
Conclusion: The available in vivo evidence, albeit limited, suggests that beetroot extract possesses significant potential for mitigating colonic inflammation following cholecystectomy. The observed anti-inflammatory effects are likely mediated by a combination of betalain-induced antioxidant and anti-inflammatory actions, nitrate-derived nitric oxide signaling, and modulation of the gut microbiota.
Investigation of Similarity of Performance of the Equations of State Available in CFTurbo For H2, N2, Ο2, CH4, CO2, and Air
Authors: Moutsios Vasileios , Margaris Dionissios , Gongolidis Mike
Published: February 2025

In this publication, a qualitative study is conducted to investigate how different equations of state perform for different gases at different temperatures and pressures. Perfect Gas, Redlich-Kwong, Aungier/Redlich-Kwong, Soave/Redlich-Kwong, Peng-Robinson, and Cool Prop are used to calculate the properties of H2, N2, Ο2, CH4, CO2, and air at a reduced temperature between 1.89 and 6.04 and reduced pressure between 0.027 and 6.661. Initially, we delved into the existing literature to locate experimental data for the specified gases. Due to a lack of experimental data, Cool Prop calculations are used as a reference due to its high accuracy (error ≤ 1%). Then, the performance of each equation for each gas is estimated. Finally, the similarity of the accuracy of each equation independently of the gas is estimated and general rules of their performance are indicated.
Innovations In Public Administration: The Experience Of Developed Countries And Prospects For Their Implementation In Ukraine
Authors:   Lviv National Environmental University, FEDYK Olga , FEDYK Serhiy ,   Ivan Franko National University of Lviv
Published: February 2025

The article explores the significance of innovation in public administration as a key instrument for modernizing state institutions and enhancing their efficiency. It analyzes the experiences of developed countries, such as Estonia, Sweden, Denmark, Singapore, Finland, and the United States, in implementing digital technologies and innovative governance models. It is noted that the digitalization of public services, the introduction of «smart cities», and the use of Big Data, and artificial intelligence significantly optimize public administration, ensure transparency, and minimize corruption risks. Special attention is devoted to the Ukrainian context. The article examines achievements in implementing tools such as the «Diia» portal, the ProZorro system, Open Data platforms, and participatory governance initiatives at the local level. It also addresses challenges faced by Ukraine, including insufficient funding, limited technical capacity, the need to harmonize legislation with European Union standards, and the necessity of transforming the culture of interaction between citizens and authorities. Considerable emphasis is placed on the importance of professional development for public sector personnel. Successful international practices, such as Singapore’s «Public Service Leadership Programme» are highlighted, along with opportunities for Ukraine in this area. The need for investments in human capital and the reform of the education system to prepare specialists with digital skills and creative thinking is underscored. The role of civil society in promoting innovation is discussed, with an emphasis on the importance of open platforms for public consultations. The potential of public-private partnerships is analyzed as a means to address critical tasks, such as infrastructure modernization and service development. It is noted that the successful implementation of innovations in the field of public administration requires political will, engagement of international assistance, and adaptation of best practices to the national context. It stresses the need for systematic monitoring and evaluation of the effectiveness of implemented changes to ensure alignment with society’s real needs. It is argued that innovation in public administration is not only a crucial factor for modernization but also a means of fostering partnerships between the government, citizens, and businesses. The article concludes that Ukraine has significant potential for implementing innovations in public administration, which would contribute to the country’s sustainable development, enhance public trust in government, and strengthen its international reputation.
The Impact Of Various Factors, Risks And Threats On The Functioning Of Enterprise Administrative Management Systems In The Context Of Globalization
Authors:   Lviv National Environmental University, FEDYK Olga , FEDYK Serhiy ,   Ivan Franko National University of Lviv
Published: February 2025

The article examines the fundamental aspects of the functioning of enterprise administrative management systems in the context of contemporary globalization processes. It analyzes the impact of various internal and external factors shaping the operational environment of enterprises, as well as explores the threats emerging in a dynamic and unstable setting. Particular attention is devoted to economic, social, technological, environmental, and political challenges faced by enterprises worldwide. The article highlights that globalization creates new opportunities for enterprises, including access to international markets and the facilitation of technology and resource exchange. However, it also intensifies competition and complicates operational conditions, requiring administrative management to demonstrate high adaptability and strategic oversight. A special emphasis is placed on ensuring enterprise resilience in crisis situations, such as economic downturns, political conflicts, or natural disasters. The study underscores the importance of innovative management approaches, particularly the integration of digital technologies such as automation and ERP systems. These technologies enable the optimization of managerial processes, cost reduction, and increased operational efficiency. Simultaneously, the critical role of cybersecurity is emphasized as a key area for ensuring informational stability and protecting enterprises from external threats. The article also places a significant focus on human resource policy. It highlights the importance of professional development for employees, the formation of a corporate culture that fosters initiative and responsibility, and the involvement of personnel in strategic processes. The necessity of investing in training, leadership skill development, and creating conditions for professional fulfillment is identified as a prerequisite for the effectiveness of administrative systems. The study explores the influence of external factors, including economic instability, changes in regulatory environments, climate challenges, and the increasing emphasis on social responsibility. In conclusion, the article states that the successful functioning of enterprise administrative management systems in today’s globalized environment depends on integrating flexibility, innovation, strategic approaches, and social responsibility. It stresses that only by considering all factors and threats; while applying a comprehensive management approach, can enterprises achieve sustainable development and ensure their competitiveness in international markets.
The Artistic Mastery of Luqmon Borikhan in Crafting Literary Characters
Authors:   Lecturer at Berdakh Karakalpak State University, Uzbekistan, Alisher Bobojanov
Published: February 2025

This article analyzes the art of character creation in Luqmon Borikhon's novel Imam Moturidi. The process of creating the character of Imam Moturidi, its historical and philosophical significance, as well as the compositional structure and plot characteristics of the novel, are examined. Additionally, the religious and philosophical views presented in the novel, artistic imagery, and the writer's attitude towards historical truth are analyzed. The article highlights that the plot of the novel is constructed in a retrospective style, with the system of characters formed based on historical sources.
Effective methods for developing communication between husband and wife in the family
Authors:   "Family and Gender" Research Institute, doctoral student, Tashkent, Uzbekistan, qizi Ugiloy Nomozova Akmaljon
Published: February 2025

In every society, the strength and peace of the family are considered among the most crucial issues. Among the problems related to the family, the matter of family communication holds particular importance. This article aims to substantiate methods of sincere and effective communication between husband and wife in the family. Within the framework of implementing this goal, a brief analysis and summary of the results from a sociological study conducted among married men and women are presented. Additionally, the views of scholars on the raised issue have been analyzed.
The practical significance of integrating prose works in developing students’ literary-aesthetic competencies
Authors:   Assistant Teacher at the Department of Uzbek Language and Literature, Karakalpak State University named after Berdakh, Uzbekistan, Avezbayeva Jamila
Published: February 2025

This article discusses the practical importance of teaching prose works in an integrated manner to develop students’ literary-aesthetic competencies in general secondary schools. It examines how an interdisciplinary approach to teaching literature can nurture spiritually mature and aesthetically sensitive individuals, thereby contributing to holistic education.
The role of Brazilian jiu-jitsu in holistic education: developing discipline, resilience, and cognitive skills through martial arts training
Authors:   Owner, Icon Jiu-Jitsu Team Norwich, Norwich, U.K., Cowan Steven Martin
Published: February 2025

This study explores Brazilian Jiu-Jitsu as an effective tool in educational practice, facilitating the development of psycho-emotional qualities, enhancing health, and improving intellectual abilities. A distinctive feature of this martial art is its integration of physical training, analytical thinking, and strategic planning while fostering personal development. The objective of this study is to examine the impact of Brazilian Jiu-Jitsu training on cognitive abilities, stress resilience, and emotional balance within educational settings.

The study highlights the influence of training on the development of self-control, confidence, and the ability to engage in objective self-assessment. Training positively affects cognitive processes, including attention span, information processing, and the organization of thought patterns. The findings confirm that Brazilian Jiu-Jitsu fosters discipline, perseverance, and the ability to overcome challenges. The presented data are relevant to the educational environment, contributing to successful adaptation to changes and the formation of effective problem-solving strategies.

The conclusion emphasizes the importance of incorporating Brazilian Jiu-Jitsu into educational practices, as martial arts serve as a universal tool for enhancing intellectual, emotional, and physical skills while fostering goal achievement across various domains.
Synthesis of a multicomponent cellulose-based absorbent for tetracycline removal from aquaculture water
Authors: Tran Uyen Bao , Vo-Tran Ngoc Thanh , Truong Khai The , Nguyen Dat Anh , Tran Quang Nhat , Nguyen Huu-Quang , Lee Jaebeom , Truong-Lam Hai Son
Published: February 2025

Excessive use of tetracycline (TC) antibiotics in aquaculture, particularly in Vietnam, has contributed to environmental contamination and economic losses. To treat the problem, this study developed a novel cellulose-based multicomponent adsorbent material (PGC) synthesized from sodium carboxymethyl cellulose and investigated factors influencing its TC adsorption capacity. The synthesis process was optimized using parameters derived from response surface methodology. The surface and structural properties of PGC were characterized, and their TC adsorption efficiency of PGC was assessed using high-performance liquid chromatography‒mass spectroscopy (HPLC-MS). Elemental analysis of PGC identified four key mechanisms governing its endothermic TC adsorption mechanism: surface complexation, electrostatic interactions, hydrogen bonding, and CH–π interactions, with surface complexation between Ca2+ and TCs being dominant. Batch adsorption experiments conducted to examine the factors influencing adsorption capacity revealed that PGC achieved up to 70% TC removal efficiency at an adsorbent dosage of 40 mg of the initial TC concentration of 60 mg L–1, pH 6–7 reaching equilibrium in 12 h. Verification experiments under optimal conditions confirmed that the adsorption process followed second-order kinetics and the Langmuir adsorption isotherm model. These findings indicate that PGC demonstrates strong potential as an effective adsorbent for the removal of TC antibiotic residues, particularly oxytetracycline, chlortetracycline, TC, and doxycycline
NOUN FORMS WITH THE STEM ON -AT- AS А WORD-FORMING BASE: APPELLATIVE AND ONYMIC WORD-FORMING TYPES
Authors: KUZMA Iryna
Published: February 2025

The article analyzes the diachronic-synchronic derivational productivity of non-initial noun forms on -ат- at the level of the word-forming paradigm, which is formed by appellative and onymic word-forming types. These are affixal nouns and adjectives, historically motivated by the base on -ат-, as well as anthroponyms and toponyms, formed as a result of transonomatization of nominative and genitive plural forms. The prerequisites and consequences of such a derivation in the modern word-formation system are revealed.
In the Ukrainian language of different periods, the word-forming paradigm of noun bases on -ат- is formed by the following appellative affixal word-forming types: noun base on -ат- + -к-о, -оньк- o, -ин-a, -ник-, ниц-я, -инець-, -ий. The most likely derivatives are plural forms mainly for the names of grouped small or paired objects (бровенятка) and genitive singular / plural (телячий).
The derivation from non-initial noun forms, in particular from nominative / genitive plural forms, is a complex and ambiguous issue in diachrony and synchrony. The onomastic derivatology is often able to unquestionably confirm such derivation, because some models of onyms supplement the list of appellative derivative types, in which various nominal morphological forms act as a derivative.
The ancient historical models of onymatization of non-initial forms of nouns that are declined according to the pattern of the t-stem are: 1. The form of the neuter noun in the nominative plural on -ат -a → masculine anthroponym on -ат-a: Іванчата. 2. The form of the neuter noun in the genitive plural on -ат- → masculine anthroponym on -ат-: Мушат. 3. The form of the neuter noun in the nominative plural on -ат-a → plural toponym on -ат-а: Ковальчата. 4. The form of the neuter noun in the genitive plural on -ат- → singular masculine toponym on -ат-: Шкурат. Today surnames and oikonyms of this type are rare.
Membangun Layanan Publik yang Partisipatif: Studi Kasus SIPRAJA melalui Perspektif New Public Governance
Authors: Doverianda Bryan , Wardiyanto Bintoro , Setijaningrum Erna
Published: February 2025

SIPRAJA (Sistem Pelayanan Rakyat Sidoarjo), developed by the Sidoarjo district government, emerged as a digital solution designed to simplify bureaucratic processes and increase citizen engagement. This study analyzes SIPRAJA through a New Public Governance (NPG) perspective, emphasizing a collaborative and citizen-centered approach to promoting inclusive and responsive governance. By integrating various stakeholders, including government agencies, private actors, and communities, SIPRAJA reflects NPG principles that prioritize co-creation and shared responsibility. This article begins by discussing challenges in traditional public administration that impede efficient service delivery. It then introduces SIPRAJA as an innovative response and explores its conceptual basis within the NPG theoretical framework. Through qualitative analysis and secondary data, this study highlights the impact of SIPRAJA in reducing administrative burden, increasing transparency, and building trust among stakeholders. However, challenges such as digital literacy gaps and infrastructure limitations were also identified, emphasizing the need for adaptive strategies. Findings show that SIPRAJA significantly contributed to the transformation of Sidoarjo's public services by promoting participatory governance, improving service accessibility and conforming to global standards for e-governance. Recommendations include increasing digital inclusion, strengthening public-private partnerships and adopting continuous monitoring mechanisms to ensure ongoing success. This research contributes to the discourse on public sector innovation by showing how NPG principles can be operationalized through technology-based initiatives such as SIPRAJA.
A comprehensive survey on arabic text classification: progress, challenges, and techniques
Authors: Hamzaoui Benamar , Bouchiha Djelloul , Bouziane Abdelghani
Published: February 2025

The exponential growth of textual data has heightened the importance of efficient text classification, a fundamental natural language processing task that assigns predefined categories to documents. This task can follow flat classification, where categories are equally structured, or hierarchical classification, which organizes categories in multi-level structures and presents additional complexities. While extensive research has advanced text classification for English, studies on Arabic text classification remain limited, particularly in hierarchical contexts. The unique features of Arabic, such as its rich morphology, diverse dialects, and syntactic complexity, pose significant challenges. This survey provides a comprehensive review of Arabic text classification by examining data sources, preprocessing steps, and feature extraction techniques, ranging from traditional methods like Bag of Words and TF-IDF to modern approaches such as neural embeddings (e.g., Word2Vec) and transformer-based models like BERT. Additionally, it explores classification techniques, from machine learning algorithms (e.g., SVM, Random Forest) to deep learning models (e.g., CNN, RNN, LSTM, GPT), and evaluates performance through metrics such as precision, recall, and F1-score. This survey aims to guide future research and innovation in Arabic text classification by addressing current advancements and challenges.
Mapping Strategy and Strategy Initiation Using the Strategic Management System and Performance Execution Excellence (SPEX2)
Authors: Fitrio Harsyatria
Published: February 2025

AbstractAs a strategic commodity, sugar is constantly monitored by the government to ensure its availability at affordable prices. Indonesia faces three main challenges in the sugar agribusiness sector: declining sugar productivity, increasing sugar imports, and price instability in the domestic market due to inefficient distribution. To address these issues, PTPN I has conducted a business mapping of the sugar sector and established targets aligned with the government’s aspirations.This study employs a qualitative descriptive method with primary data collected through in-depth interviews and observations related to the strategy and performance execution excellence management system (SPEX2). The findings indicate that PTPN I’s development strategies include enhancing operational efficiency, improving employee skills, and modernizing technology to boost productivity and sugar quality. External strategies respond to opportunities and threats, supported by government policies aimed at developing the sugar industry. Moreover, PTPN I emphasizes financial, customer, internal business process, and learning and growth perspectives, with priorities centered on increasing revenue, business development, and enhancing human resource competencies.Keywords:  Strategy and performance execution excellence management system (SPEX2)
TOI-6038 A b: A Dense Sub-Saturn in the Transition Regime between the Neptunian Ridge and Savanna
Authors: Baliwal Sanjay , Sharma Rishikesh , Chakraborty Abhijit , Nikitha K. J. , Castro-González A. , Bhaskar Hareesh G. , Khandelwal Akanksha , Latham David W. , Bieryla Allyson , Bourrier Vincent , Prasad Neelam J. S. S. V. , Bharadwaj Kapil K. , Lad Kevikumar A. , Nayak Ashirbad , Joshi Vishal , Eastman Jason D.
Published: February 2025

We present the discovery and characterization of a sub-Saturn exoplanet, TOI-6038 A b, using the PARAS-2 spectrograph. The planet orbits a bright (m

V
 = 9.9), metal-rich late F-type star, TOI-6038 A, with T
eff = 6110 ± 100 K,

log
g
=
4.11

8

−
0.025

+
0.015

, and

[
Fe/H
]
=
0.12

4

−
0.077

+
0.079

dex. The system also contains a wide-orbit binary companion, TOI-6038 B, an early K-type star at a projected separation of ≈3217 au. We combined radial velocity data from PARAS-2 with photometric data from the Transiting Exoplanet Survey Satellite for joint modeling. TOI-6038 A b has a mass of

78
.

5

−
9.9

+
9.5

M
⊕

and a radius of

6.4

1

−
0.16

+
0.20

R
⊕

, orbiting in a circular orbit with a period of

5.826731

1

−
0.0000068

+
0.0000074

days. Internal structure modeling suggests that ≈74% of the planet's mass is composed of dense materials, such as rock and iron, forming a core, while the remaining mass consists of a low-density H/He envelope. TOI-6038 A b lies at the transition regime between the recently identified Neptunian ridge and savanna. Having a density of

ρ

P

=
1.6

2

−
0.24

+
0.23

g

cm

−
3

, TOI-6038 A b is compatible with the population of dense ridge planets (ρ
P ≃ 1.5–2.0 g cm−3), which have been proposed to have reached their close-in locations through high-eccentricity tidal migration (HEM). First-order estimates suggest that the secular perturbations induced by TOI-6038 B may be insufficient to drive the HEM of TOI-6038 A b. Therefore, it is not clear whether HEM driven by a still undetected companion or early disk-driven migration brought TOI-6038 A b to its present-day close-in orbit. Interestingly, its bright host star makes TOI-6038 A b a prime target for atmospheric escape and orbital architecture observations, which will help us to better understand its overall evolution.
Mort et folie : comment ne pas parler de la mort
Authors: Urbano Pedro
Published: February 2025

Le Moyen Âge a été l’une des périodes les plus meurtrières de l’histoire européenne, peut-être la plus dévastatrice. De nombreuses pages seraient nécessaires pour décrire l’étendue des catastrophes et calamités qui ont ravagé l’Europe médiévale, au point de transformer le continent en une immense morgue métaphorique. Les populations européennes n’étaient nullement préparées à affronter une telle horreur. L’une des conséquences fut l’émergence de la folie comme phénomène social, au-delà du simple trouble mental individuel. Comment rationaliser l’irrationnel ? Comment faire face à l’irrationalité de la mort de masse ? Umberto Eco, bien qu’abordant cette question dans un autre contexte, offre une piste: face à la réalité inéluctable de la mort, le seul recours est le rire. En un sens, c’est ce que les Européens médiévaux ont fait en étant constamment guettés par la mort. Nous avons beaucoup à apprendre de l’histoire du Moyen Âge, d’autant plus que la « Grande Mort » n’a pas disparu au xxi ᵉ siècle. Des pandémies, peut-être plus mortelles que celle de 2019, et la menace toujours présente d’une guerre nucléaire totale, pourraient la raviver. L’ Homo sapiens est définitivement capable d’affronter la mort, depuis au moins la fin du Pléistocène, mais il n’a jamais été préparé à affronter la « Grande Mort », celle qui frappa les populations européennes au Moyen Âge.
Deuil périnatal et réseaux sociaux
Authors: Camps François-David , Issartial Laure
Published: February 2025

Cet article s’intéresse au vécu psychique des femmes traversant un deuil périnatal et aux outils dont elles peuvent se saisir pour tenter de traverser cette expérience. Au cours de cette recherche, nous avons essayé de comprendre comment l’utilisation des sites de réseaux sociaux pouvait être perçue et investie potentiellement en tant que ressource soutenante étayante et élaborative psychiquement par les mères traversant une situation traumatique de deuil périnatal. Cette recherche s’est développée à partir d’une revue théorique ainsi que de entretiens cliniques auprès de trois jeunes femmes d’une trentaine d’années ayant vécues un deuil périnatal. Cette dernière vise à montrer comment l’utilisation de réseaux sociaux rendrait possible pour ces mères endeuillées un premier pas vers une élaboration psychique de leur expérience traumatique de deuil. Les réseaux sociaux viendraient fournir une forme d’appartenance et de soutien communautaire virtuels que ces femmes ne pouvaient pas trouver au sein de leur entourage, leur permettant ne plus se sentir seule ou encore se retrouver dans leur identité de mère.
Incomplete RPE and Outer Retinal Atrophy (iRORA) Development in Eyes With Fellow-eye Neovascular Age-related Macular Degeneration
Authors: Choi Hanna , Corradetti Giulia , Lindenberg Sophiana , Karamat Ayesha N. , Oncel Deniz , Liu Henry , Gnanaraj Ramya , Fasih-Ahmad Sohaib , Marion Kenneth M. , Baker Kirstie L. , Gulati Shilpa , Foster Bradley , Lam Andrew , Sadda SriniVas R. , Lally David R.
Published: February 2025

Background and Objective

The utility of incomplete retinal pigment epithelium (RPE) and outer retinal atrophy (iRORA) in intermediate age-related macular degeneration (iAMD) as a clinical endpoint is not yet elucidated. We aim to understand the time to iRORA development in iAMD.

Patients and Methods

Eyes with iAMD without iRORA of subjects with fellow-eye neovascular AMD (nAMD) were identified from visits between 2010 and 2019 at a tertiary clinic. Spectral Domain Optical Coherence Tomography 512 × 128mm macular cubes (Cirrus HD-OCT, Zeiss) were assessed for time to first detection of iRORA and complete RPE and Outer retinal atrophy (cRORA) at 24 months. Up to three iRORA lesions were followed. Univariable Cox regressions evaluated baseline OCT characteristics, age, and gender as predictors for iRORA or cRORA development. Baseline OCT characteristics included intraretinal hyperreflective foci (IHRF), subretinal drusenoid deposits (SDD), hyporeflective drusen cores (hDC), and drusen volume measured with semi-automatic segmentation of Bruch's membrane to RPE.

Results

In 101 eyes of 101 subjects (64% female; median 81 years old), 28.70% (
n
= 30) developed iRORA whereas 2.97% (
n
= 3) developed cRORA without iRORA at 24 months. Median (range) time to first iRORA or cRORA was 20 (12 to 24) months. The presence of baseline IHRF was associated with increased risk of iRORA development at month 24 (HR = 2.28, 95% CI: 1.14 to 4.56;
P
value = 0.019).

Conclusion

In subjects with fellow-eye nAMD, approximately one third of iAMD eyes developed iRORA at 24 months. Intraretinal hyperreflective foci was associated with a two-fold increased risk in iRORA development.

[
Ophthalmic Surg Lasers Imaging Retina
2025;56:XX–XX.]
Preliminary Experience With a Novel Titanium Macular Buckle in the Management of Myopic Maculopathy
Authors: Yalcinbayir Ozgur , Ozdek Sengul , Durukan Ali Hakan , Shousha Mohsen Abou , Shafy Muhammad Samir Abd Al , Sonmez Kenan , Kose Huseyin Egemen , Ozdemir-Zeydanli Ece , Garg Mohit
Published: February 2025

The objective of this study was to report the initial experiences of seven surgeons using a titanium macular buckle (TMB) for the treatment of myopic maculopathy. The records of 11 cases that underwent TMB placement, with or without concomitant vitrectomy, were reviewed. Collected data included demographics, type of maculopathy, pre-operative and postoperative ophthalmic findings. The intraoperative utilization of pars plana vitrectomy and any associated complications were also documented. The indications for surgery included posterior pole retinal detachment with maculoschisis, maculoschisis with an epiretinal membrane, myopic macular hole with posterior pole retinal detachment, isolated maculoschisis, and myopic macular hole. Eight of the 11 cases underwent combined titanium macular buckle placement and vitrectomy, while three patients received buckle placement without vitrectomy. Partial or complete resolution of the pathology was achieved in all cases. Best-corrected visual acuity improved in 10 out of 11 cases following surgery. A scleral perforation occurred intraoperatively in one case. The patients were followed up for a mean duration of 6.0 ± 2.3 months (range: 2 to 10 months). TMB may serve as a valuable adjunct in the surgical repair of myopic maculopathy requiring intervention.

[
Ophthalmic Surg Lasers Imaging Retina
2025;56:XX–XX.]
Challenge-Based Learning in Biomedical Engineering
Authors: Valencia-Lazcano Anaí Alicia , Fuentes-Álvarez Rubén , Cruz-Sandoval Marco , Miranda-Hernández Juan Carlos , Membrillo-Hernández Jorge
Published: February 2025

One of the primary objectives of higher education (HE) is to produce specialized human resources with the necessary competencies for the challenges encountered in our professional lives and our complex environment. One form of experiential education for biomedical engineering students is to expose them to real situations so that, based on acquired knowledge, they develop highlevel disciplinary competencies that prepare them for a future job with greater expectations. This report analyzes the use of teaching strategies such as challenge-based learning (CBL) for the development of technical skills through the design and manufacture of a walking aid device, the implementation of effective methods for the development of medical devices, and the identification of sustainability in engineering. A tournament skills event evaluated the results by highlighting specific solution proposal points. This study is an illustrative case that provides significant evidence of the effectiveness of CBL and can serve as a model for pedagogically sensitive evaluation of the engineering classroom by integrating blended learning schemes using gamification techniques.
Improving Monitoring of Heart Rate Using an RGB Camera and OpenCL Architecture: Towards a Heterogenous Embedded System Implementation
Authors: El Khadiri Zakaria , Latif Rachid , Saddik Amine
Published: February 2025

Conventional heart rate (HR) monitoring typically relies on contact sensors, but recent advancements demonstrate the potential of non-contact methods using RGB cameras for photoplethysmography (PPG)-based HR analysis. This study presents a real-time, non-contact HR monitoring system that applies signal processing techniques to accurately derive HR from facial video data. Our approach mitigates environmental and motion-induced noise through image enhancement and signal filtering while utilizing Fourier analysis to extract physiological signals from the processed PPG data. Implemented on a heterogeneous CPU-GPU system with high-level synthesis (HLS) for parallel acceleration, our proposed system achieves a substantial improvement in processing efficiency, outperforming the baseline method by a factor of 3.53 in processing time. These results underscore the system’s potential for integration into embedded healthcare monitoring applications, offering a pathway for reliable, non-invasive physiological monitoring.
Patent Landscapes in Digital Health: Insights from Smartphone Technologies
Authors: Morishita Wataru , Takayama Kojiro , Saotome Chikako
Published: February 2025

Digital health, such as mobile health apps, has garnered significant attention, leading to an increase in patent applications. This study investigates patent applications related to digital health using smartphones to elucidate the overall state of patenting in this domain and the characteristics of applicants based on nationality and industry type. We analyzed 11,139 patent families filed between 2015 and 2019, featuring the international patent classification (IPC) code G16H (healthcare informatics) and keywords related to smartphones. Our findings indicate that the United States (US) is the most significant market and leader in digital health technology. Correspondence analysis revealed that applications from the US and Europe share similar content, while those from Japan and China exhibit distinct characteristics. Additionally, industry-based correspondence analysis showed that patents from the machinery industry are often related to imaging technology, whereas those from the information technology (IT) sector are primarily associated with medical information-based applications.
Application of Convolutional Neural Networks in Skin Disease Prediction: Accuracy and Efficiency in Dermatological Image Analysis
Authors: Iparraguirre-Villanueva Orlando , Cabanillas-Carbonell Michael
Published: February 2025

The use of dermatological images and convolutional neural networks (CNNs) to predict skin diseases is one of the most promising applications of data science to improve the diagnosis and treatment of skin diseases. The aim of this work was to achieve maximum accuracy and efficiency in skin disease prediction using dermatological images and CNN models. Based on dermatological images, the ability of five CNN models to predict skin diseases was evaluated. The ResNet50, Inception V3, VGG-19, DenseNet201, and EfficientNet models were evaluated using the Kaggle HAM10000 (human against machine with 10000 training images) dataset. The metrics used were accuracy, recall, and F1 score. As a result, the study found that skin disease classification has variable performance. VGG-19 and DenseNet201 showed high values for accuracy, recall, and F1 score, with accuracy close to 98%. These models demonstrated an effective ability to identify and classify different types of skin diseases. In contrast, ResNet50 and Inception V3 obtained mixed results, while EfficientNet showed variable results in predicting skin diseases from dermatological images. Finally, the importance of choosing the right CNN model to predict skin diseases from dermatological images can be highlighted. VGG-19 and DenseNet201 performed well in classifying various skin diseases, which could be useful for developing dermatological diagnostic support systems.
Métaphysique et politique
Authors: Tardivel Émilie
Published: February 2025

Cet article met en rapport deux livres de Jean-Luc Marion appartenant à deux champs distincts : La Métaphysique et après (2023) et la Brève apologie pour un moment catholique (2017). Il établit que La métaphysique et après permet de comprendre la Brève apologie dans ses motifs principaux et de mettre en évidence une lecture de l’histoire de la philosophie politique qui fasse pendant à la lecture phénoménologique de l’histoire de la métaphysique. Cette lecture se fonde sur une méthode incluant deux parties : une pars destruens, consistant à décrire la transposition politique des figures modernes de la métaphysique, et une pars construens, visant à redéfinir les concepts politiques fondamentaux sur la base du dépassement des figures modernes de la métaphysique.
Marions und Heideggers Metaphysikbegriff im Vergleich
Authors: Schweidler Walter
Published: February 2025

Le point commun entre Marion et Heidegger est leur compréhension paradoxale de la métaphysique comme une recherche de connaissances finales qui, étant inconsciemment dirigée vers soi-même, rend son accomplissement impossible. Ce qui différencie les deux, c’est la manière dont ils envisagent cette impossibilité. Pour Heidegger, le dépassement de la métaphysique ne laisse aucun espace pour un nouveau départ de la philosophie. Marion quant à lui pense que l’impossible accomplissement de la recherche métaphysique permet un tournant de la personnalité de celui qui a initié la recherche. Ce dernier émerge de la recherche comme « l’adonné », le destinataire d’une donation qu’il pourrait recevoir seulement par le processus inachevable et irréalisable de la métaphysique. Le fondement théorique de cette conception de Marion réside dans les concepts d’objet impossible et d’événement possible ainsi que dans son idée du phénomène saturé.
La métaphysique des Temps modernes ou l’époque du sujet
Authors: Mehl Édouard
Published: February 2025

Comme le frontispice du Saggiatore de Galilée est encadré par deux figures étrangement semblables, personnifiant la mathématique et la philosophie naturelle, l’œuvre du philosophe Jean-Luc Marion repose sur deux colonnes : la « métaphysique » et la « phénoménologie ». Pourtant, cette belle symétrie cache une difficulté ou un problème : J.-L. Marion étudie les philosophes relevant de « l’histoire de la métaphysique », mais ne parle jamais de la métaphysique de ces auteurs. Il n’y a pas, chez l’historien Jean-Luc Marion, de « métaphysique de Descartes », ni de « métaphysique de Spinoza », ou de Leibniz, ou de Malebranche. Il faut donc éclairer ce concept de métaphysique dont l’histoire ne se confond pas avec celle des doctrines, ni avec celle des corpus, et qui n’a, étrangement, qu’une seule époque — moderne — à la pensée de laquelle la philosophie est indéfiniment, i.e. définitivement assignée.
La beauté de l’épouse selon Ben Sira
Authors: Lavoie Jean-Jacques
Published: February 2025

Dans le livre de Ben Sira, trois textes portent sur la beauté de l’épouse (7, 19 ; 26, 13-18 et 36, 27[22 Hébreu]). Dans cet article, l’auteur cherche à répondre aux questions suivantes : quels sont les idéaux de Ben Sira au sujet de la beauté de l’épouse ? Ses idéaux sont-ils aliénants pour les femmes ou favorisent-ils leur autonomisation et leur émancipation ? De quelle manière les discours de Ben Sira sur la beauté des épouses sont-ils susceptibles d’affecter les rapports de pouvoir entre les sexes ? Les idéaux de Ben Sira au sujet de la beauté, tels qu’ils sont promus dans le texte hébraïque, correspondent-ils en tout point aux idéaux de son petit-fils, qui a traduit en grec le livre de son grand-père ? En somme, quels sont les enseignements du livre de Ben Sira au sujet de la beauté des épouses ?
Les espaces religieux de l’Église orthodoxe de Roumanie en France : héritages et métamorphoses
Authors: Lemonnier Jean-Michel
Published: February 2025

Autrefois largement circonscrits à Paris et à quelques grands centres urbains, les lieux de présence du christianisme orthodoxe roumain se redéploient aujourd’hui dans l’ensemble de l’espace français. Depuis la chute du communisme, des flux migratoires roumains et moldaves importants ont totalement métamorphosé l’organisation spatiale et sociale de cette Église hors frontières. Cet article entend montrer comment et avec quels effets cette Église orthodoxe roumaine fait face à cet enjeu migratoire qui bouleverse radicalement ses anciennes pratiques.
Remote working practices and its impact on the quality of life across the island of Ireland
Authors: Boullet Vanessa
Published: February 2025

Remote working and its impact on the quality of life in Ireland has been significantly influenced by various factors such as the increased participation of women in the labour market, digitalisation and the flexibilisation of the labour market. The various lockdown measures imposed during the Covid-19 pandemic accelerated this transformation by forcing many employees to implement remote working. Although working from home offers advantages such as flexibility and savings in time and money, it also has disadvantages, such as social isolation and communication difficulties. The Irish government has examined the issue since 1998 and has published several reports. Before the pandemic, only a fraction of employees worked from home, but after the pandemic it became commonplace, with increased interest in a blended model. However, the shift is not without its challenges, including the work-life balance, and increased gender inequalities. To regulate such practices, the European Union has encouraged Member States to draw up national action plans, but regulations in Ireland remain unclear. Furthermore, the particular situation of cross-border workers between Ireland and Northern Ireland presents additional challenges in terms of social benefits, social security and taxation. In conclusion, remote working can have both positive and negative impacts on workers’ quality of life, and it is up to each stakeholder, including employees, employers and government, to take steps to mitigate the risks and maximise the benefits of this practice.
The impact of chronic disease on wellbeing and quality of life: The case of Long Covid in Britain
Authors: Dalingwater Louise
Published: February 2025

This article aims to illustrate the effects of the chronic illness Long Covid on health and wellbeing in Britain. It will examine the evidence on this condition and its impact on wellbeing through what has been termed “living systematic reviews”, which refer to data which is updated with relevant new evidence as it becomes available, recognising that this is both a heterogeneous condition and that the literature on Long Covid has become redundant as the disease has progressed. Since the article focuses on the impact on British people’s lives, it will also examine a collection of narratives which are available online through Long Covid health advocacy websites.
Teoría crítica andina: un diálogo entre José Carlos Mariátegui y Bolívar Echeverría
Authors: Ramos César Miguel Salinas
Published: February 2025

Partiendo del análisis del contexto histórico de los Andes, de la emergencia de las izquierdas, se revisan los principales protagonistas y acontecimientos históricos en este proceso. Nos enfocamos en examinar la modernidad latinoamericana desde una perspectiva crítica y situada, mediante un diálogo entre José Carlos Mariátegui (1894‑1930) y Bolívar Echeverría (1941‑2010). Nos centramos en la relación y el tránsito del Estado colonial a las repúblicas, principalmente mediante el análisis de la soberanía. La metodología consistió en una revisión bibliográfica de textos clásicos de ambos autores y producciones académicas calificadas de comentadores y especialistas. También se revisaron textos de la teoría crítica de origen en Frankfurt, especialmente de Walter Benjamin (1892‑1940). Como resultado, la dominación y las posibilidades emancipatorias en los Andes existen en la relación dialéctica entre sentires, praxis y pensares comunitarios.
Editorial
Authors: Iddagoda Anuradha
Published: February 2025

No abstract available
Impact of Work Life Balance on Job Satisfaction with Mediating Relationships of Employee Engagement and Organizational Commitment
Authors: Shyamadanthi Dilhara , Kaluarachchige Indika Priyantha
Published: February 2025

Work Life Balance and its impact on Job Satisfaction is a burning topic in the field of HRM due to its implications on Human Capital. Defining the ‘right’ balance between “Work” and “Life” is indeed a challenge since it differs according to the person and the context. Similarly, Job Satisfaction is also a highly subjective phenomenon. This research work examines the effect of Work Life Balance on Job Satisfaction with the mediating relationships of Employee Engagement and Organizational Commitment with reference to the non-executive staff of a government bank in Sri Lanka in order to gain insight on designing HR policies in boosting job satisfaction leading to better performance. Primary data was collected from 202 respondents and bivariate and multivariate analyses were used to analyse the responses. The findings indicate a negative and significant relationship between Work Life Balance and Job Satisfaction. It is assumed that it may have occurred due to the prevailing economic condition of the country. Thus, inflation and uncertainties may have pushed the need for other humane work-related conditions to the background. Further, Employee Engagement mediates the relationship between Work Life Balance and Job Satisfaction. A negative and insignificant relationship is depicted between Work Life Balance and Organizational Commitment whereas a positive and significant relationship is depicted between Organizational Commitment and Job Satisfaction. According to the findings, maintaining the favourable Work Life Balance Policies effectively, while enhancing Employee Engagement and Organizational Commitment would help boost Job Satisfaction. Organizations may also take measures to avoid employee burnout in the long run due to work life imbalance and thereby maintain a sustainable level of job satisfaction to reach the expected level of employee performance in business organizations.
Effect of Bonding Pressure on Thermal Performance of Graphene-enhanced Thermal Interface Materials for Immersion Cooling Applications
Authors: Harr Kristoffer , Wang Yuanyuan , Yasin Kurban , Chen Jiabin , Chen Jin , Möller Johan , Liu Johan
Published: February 2025

Graphene, due to its exceptional mechanical, optical, electrical, physical and thermal properties, has attracted strong interest for both fundamental studies and real applications. Among all these properties, the extraordinary high thermal conductivity makes graphene an ideal cooling material for power devices and systems. In mean time, rapid growth of information and AI technology continues to push power density and integration level in electronics devices, leading to an increase in greater heat dissipation causing lower performance, and shorter operating life. In this paper, the technology of a new graphene-enhanced thermal interface material (GT-TIM) manufacturing process is described. The effect of bonding pressures on thermal performance of the GT-TIM with different thicknesses is presented. The immersion test up to 1-month in immersion condition was carried out. The results show that the GT-TIM can be exposed to very high bonding pressure without delamination, well beyond normally used bonding pressure regions and extremely low thermal resistance in the range of 4-5 Kmm2/W at 40 psi (276kPa) at a thickness of 0,2 mm. In a typical biocompatible coolant environment, the thermal performance is basically intact after one month´s exposure.

It is thus concluded that that this class of the novel GT-TIM has very interesting feature that can potentially be used for many large power cooling applications, especially for immersion cooling.