bluuebunny/crossref_metadata_2025 huggingface dataset:
Áhrif hjúkrunar á gæði lífslokameðferðar á gjörgæsludeildum. Samþætt fræðileg samantekt.
Authors: Birgisdóttir Anna Halla , Gunnarsdóttir Þóra Jenný
Published: January 2025

Tilgangur
Tilgangur þessarar samantektar var að samþætta niðurstöður
rannsókna um árangursríka umönnunarþætti hjúkrunar gagnvart
gjörgæslusjúklingum við lífslok og fjölskyldum þeirra.
Aðferð
Samþætt fræðileg samantekt var framkvæmd með aðferð Whittemore
og Knafl. Til að tryggja gæði rannsókna í samantektinni var stuðst við
gæðamatsverkfæri frá Joanna Briggs Institute. Leitað var að nýlegum
rannsóknum í PubMed- og CINAHL- gagnagrunnum á tímabilinu maí
2020 til febrúar 2023. Rannsóknir voru valdar, greindar og niðurstöður
birtar samkvæmt leiðbeiningum PRISMA (“Preferred Reporting Items for
Systematic Reviews and Meta-Analyses statement”).
Niðurstöður
Tuttugu og tvær rannsóknir voru í samantektinni. Niðurstöður sýndu
fram á mikilvægi framlags hjúkrunarfræðinga til að tryggja góða
einkennameðferð gjörgæslusjúklinga við lífslok og til margs konar
stuðnings við aðstandendur til að gera upplifun þeirra betri. Fjögur þemu
greindust: „Mikilvægi þekkingar hjúkrunarfræðinga á hjúkrun við lífslok“,
„Góð einkennameðferð við lífslok“, „Þátttaka fjölskyldu í umræðum um
meðferðartakmarkanir gjörgæslusjúklinga“ og „Fjölskyldumiðuð hjúkrun
við lífslok gjörgæslusjúklinga“. Niðurstöður benda til þess að bæta megi
einkennameðferð gjörgæslusjúklinga við lífslok. Þá virðist þörf á auknum
stuðningi frá heilbrigðisstarfsfólki til fjölskyldna sem myndi auðvelda þeim
þátttöku í ákvörðunum um meðferðir eða takmarkanir þeirra við lífslok
ástvina á gjörgæslu.
Ályktanir
Mikilvægt er að menntun og þjálfun í líknarmeðferð og lífslokameðferð
sé aðgengileg fyrir alla hjúkrunarfræðinga sem vinna á gjörgæslu. Þessi
yfirlitsgrein tekur saman leiðbeiningar um hjúkrun sem mögulega nýtist
hjúkrunarfræðingum við lífslokameðferð á gjörgæsludeild.
Lykilorð
Lífslokameðferð, gjörgæsla, líknarmeðferð, fjölskylduhjúkrun, samskipti
Eldra fólk sem kom á bráðamóttöku og var vísað á greiningarmóttöku öldrunarlækningadeildar Landspítala árin 2016-2018: heilsufar og afdrif
Authors: Hjaltadóttir Ingibjörg , Ólafsdóttir Karítas , Bergmundsdóttir Sigrún Berglind , Jónsdóttir Anna Björg
Published: January 2025

Tilgangur
Með fjölgun aldraðra á komandi árum er líklegt að þeim fjölgi sem eru
fjölveikir, með skerta færni eða hrumleika. Því verður aukin þörf fyrir
sérhæfða heilbrigðisþjónustu og mikilvægt að bregðast við með viðeigandi
meðferð til að fyrirbyggja versnun á heilsufari, þörf á sjúkrahúslegu
eða vistun á hjúkrunarheimili. Markmið rannsóknarinnar var að skoða
heilsufar, færni og heimaþjónustu þeirra sem vísað var á greiningarmóttöku
öldrunarlækningadeildar á Landspítala. Einnig að skoða hvernig heilsufar
og færni tengist andláti og flutningi á hjúkrunarheimili innan árs frá komu.
Aðferð
Rannsóknin er afturskyggn þversniðsrannsókn á sjúkraskrárgögnum
einstaklinga sem komu á greiningarmóttöku (GM), auk upplýsinga um
andlát og flutning á hjúkrunarheimili (N=161). Lýsandi og greinandi
tölfræði var notuð til að greina gögnin og aðhvarfsgreining hlutfalla
var notuð til að greina forspárþætti fyrir andláti eða flutningi á
hjúkrunarheimili.
Niðurstöður
Meðalaldur var 84,4 ár og 71,6% voru konur. Þeir sem höfðu tvær eða fleiri
komur á bráðamóttöku á síðastliðnum 90 dögum voru 62 (43,9%). Komum
á bráðamóttöku fækkaði hjá einstaklingunum um 82% þegar borið var
saman 30 daga tímabil fyrir og eftir komu á GM en fækkaði um 70% ef
tímabilið var 90 dagar fyrir og eftir komu á GM (p=0,001). Eftirfarandi
þættir sýndu auknar hlutfallslíkur á að einstaklingarnir létust eða flyttu
á hjúkrunarheimili innan árs frá komu á greiningarmóttöku: voru með
heimahjúkrun (OR 3,44 (CI 1,115–10,592), p<0,032); skert sjálfsbjargargeta
við að klæðast (OR 5,60 (CI 1,702–18,458), p<0,005); byltur (OR 4,38 (CI
1,333–14,418), p<0,015); innlögn á bráðasjúkrahús (OR 3,79 (CI 1,004–
14,295), p<0,049).
Ályktanir
Sérhæfð þverfagleg þjónusta við hrumt eldra fólk í hættu á alvarlegum
heilsubresti getur tryggt viðeigandi meðferð, fækkað komum á
bráðamóttöku og stutt við sjálfstæða búsetu.
Lykilorð
eldra fólk, göngudeild, heilsufar, færni
Reformasi Sektor Energi Indonesia: Mendukung Transisi Energi Dalam Rangka Meningkatkan Ketahanan Energi dan Ekonomi
Authors:   Putnomo Yusgiantoro Center
Published: January 2025

Di era globalisasi yang semakin kompleks ini, tantangan di sektor energi juga semakin beragam. Indonesia dihadapkan pada lonjakan permintaan energi seiring pesatnya perkembangan ekonomi dan pertumbuhan jumlah penduduk. Pada saat ini, sektor energi nasional masih bergantung pada bahan bakar fosil seperti batu bara, minyak, dan gas alam yang mendominasi bauran energi. Ketergantungan ini dapat menimbulkan risiko bagi ketahanan energi dan menyulitkan Indonesia dalam memenuhi komitmen lingkungan. Oleh karena itu, sektor energi di Indonesia memerlukan reformasi untuk dapat mengatasi tantangan kebutuhan energi yang terus meningkat, memperkuat ketahanan energi, dan memenuhi tuntutan keberlanjutan.

Pemerintah Indonesia memiliki target bauran energi baru terbarukan sebesar 23% di tahun 2025. Pada semester I tahun 2024, realisasi energi terbarukan baru mencapai 13%. Hal ini menandakan bahwa masih banyak tantangan yang harus diatasi untuk mencapai target tersebut. Tantangan tersebut mulai dari kendala kebijakan, keterbatasan infrastruktur, hingga keterbatasan kapasitas teknis dan tenaga kerja terampil serta dukungan pendanaan energi terbarukan. Isu lain yang masih menjadi hambatan dalam proses transisi energi adalah inkonsistensi penerapan kebijakan dan lemahnya koordinasi lintas sektor dan juga koordinasi antara pusat dan daerah.
Resultados de la implementación de módulo embebido de conversión de tensiones en motores trifásicos
Authors: Vargas Ortega Jortin De Jesús , Moreno Paniagua Carlos Mario
Published: January 2025

Se presentan los resultados del diseño y la implementación de un módulo electrónico embebido en los motores eléctricos de inducción, que permite la conexión de estos, en instalaciones monofásicas con la finalidad de incrementar la eficiencia en el uso de fuerza motriz en zonas no industriales. En estos lugares es creciente la proliferación de pequeños negocios, que utilizan potencia eléctrica, alimentada desde acometidas monofásicas, que generalmente presentan una baja eficiencia en comparación con el uso de las trifásicas. La baja eficiencia en dichas instalaciones se debe a la utilización generalizada de motores eléctricos de inducción, monofásicos y trifásicos, alimentados con tensión de una fase.
Modelado de la admisión de la carga en una metodología secuencial para combustión HCCI
Authors: Heredia Quintana Sebastián , Morales-Rojas Andres David , Bedoya Caro Iván Darío
Published: January 2025

El aprovechamiento de desechos o biomasa para la producción de electricidad se ha planteado como una alternativa energética y ambiental en zonas urbanas y rurales. A escalas de generación menores a 75 kW, el uso de motores de combustión interna en modos de operación con combustión avanzada permite abordar desafíos de técnicos y de eficiencia que se encuentran cuando se utilizan combustibles gaseosos de origen renovable en tecnologías convencionales. El uso de herramientas de simulación numérica permite optimizar el desempeño de estas nuevas tecnologías, así como abordar y entender los fenómenos complejos que se dan al interior del cilindro motor. En este estudio se presenta el uso de una metodología numérica secuencial, CFD – cinética química detallada, para analizar la distribución térmica y másica de la carga previo a la ignición y desarrollo de la combustión en un motor diesel modificado operando con biogás a 1800 rpm, observándose cómo los patrones de flujo conducen a una acumulación de la carga en las zonas de mayor temperatura y con ello a cortas duraciones de la combustión aún para condiciones de combustión retrasada.
Overlapping DNA methylation changes in enhancers in clonal cytopenia of undetermined significance and myelodysplastic neoplasm patients with TET2, IDH2, or DNMT3A mutations
Authors: Kaastrup Katja , Tulstrup Morten , Hansen Jakob W. , Schöllkopf Claudia , Raaschou-Jensen Klas , Ørskov Andreas D. , Porse Bo , Jones Peter A. , Weischenfeldt Joachim , Gillberg Linn , Grønbæk Kirsten
Published: January 2025

Not available.
Putting the brakes on cyclin C - a promising strategy to cure B-cell acute lymphoblastic leukemia?
Authors: Muddineni Siva Sai Naga Anurag , Milyavsky Michael
Published: January 2025

Not available.
Un mundo de peticiones. Maestras ante el Consejo Nacional de Educación y el Parlamento. 1886-1904
Authors: Erijman Paula
Published: January 2025

Este trabajo estudia las peticiones que maestras de instrucción primaria presentaron ante el Congreso Nacional argentino y el Consejo Nacional de Educación para obtener jubilaciones, pensiones y aumentos de haberes, entre 1886 y 1904. A partir de su análisis la investigación busca poner de relieve el peso político de esta manera de demandar. Las peticiones iluminan una serie de reclamos laborales que no se plasmaron necesariamente en huelgas o conflictos de gran resonancia, pero que revelan otros modos y espacios para defender lo que se creía justo, así como un repertorio de acciones posibles en un tiempo y un lugar. En este artículo se explora cómo aquellas estuvieron acompañadas de distintos ámbitos de intercambio de información, de acompañamiento mutuo entre peticionantes y de presión dentro del Parlamento. Además, se examina cómo estas solicitudes contribuyeron a flexibilizar los márgenes de la legislación vigente y los modos de gestionar estos retiros. Se estudia cómo las maestras pusieron en juego los vínculos generados durante sus años de docencia con funcionarios y legisladores y de qué modo hicieron las presentaciones de sus peticiones ante el Congreso y el Consejo Nacional de Educación. Además, se observa cómo crearon, reunieron y preservaron papeles para certificar sus años de servicios y otra información laboral.
La pesquisa combina el análisis de estas peticiones con diferentes corpus documentales, tales como registros nacionales de leyes y decretos, diarios de sesiones del Congreso, informes del área educativa y censos. Con las herramientas metodológicas de la historia social con perspectiva de género, busca arrojar luz sobre la relación entre las trayectorias laborales de unas maestras de la capital y las colonias y la obtención de jubilaciones y pensiones.
Ingenuidad, silencio y ausencia. Tácticas para permanecer como directoras y maestras (1925-1945)
Authors: Caldo Paula
Published: January 2025

El objetivo del presente artículo es ensayar una aproximación biográfica a las trayectorias de dos maestras, Teodolinda y Dominga, que dejaron pocas marcas en los archivos. Nos proponemos estudiar las tácticas desplegadas por ambas para sobrevivir al oficio docente en el doble rol de maestra y directora. Atenderemos en estas experiencias cómo ellas tramitaron las reglas generales de conducta y moral que rigieron en la época (1925-1945). Para llevar adelante la propuesta nos valemos de aportes propios de la historia de la educación en clave cultural y de la historia de las mujeres en perspectiva de género. El corpus que sometemos a análisis crítico se compone de dos expedientes de cesantías encontrados en el fondo documental del Consejo Nacional de Educación sito en el Archivo General de la Nación. Los resultados permiten inferir que estas mujeres ordenaron una serie de tácticas para dar curso a su labor docente junto con el sostenimiento de sus vidas amorosas, desafiando así los límites de las buenas maneras prescriptas por el sistema educativo.
Service Quality of Museums for Sustainable Tourism: An Empirical Study of Museums in Bangladesh
Authors: Sharmin Dilruba , Haque Farina
Published: January 2025

Museums are the major cultural resources of a country that emphasize tourism and economic growth. For this, the service quality is important, and should be measured by systematic methods and analysis on a yearly basis. In Bangladesh, due to the lack of knowledge, these cultural resources are not properly utilized and managed, which affects the conservation and preservation of our historical resources as well as national development. This study aims to understand the quality of service of museums in Bangladesh. It helps us understand the concepts prominent among visitors engaging in museum experiences and the barriers for museums to provide a better quality of service to their visitors. The study was conducted on 16 renowned museums across three divisions of Bangladesh: Dhaka, Rajshahi, and Chattogram. Field visits and in-depth interviews are applied as a methodology for data collection. The study suggests that most of the known Bangladeshi museums need help in providing a better quality of service for their visitors due to inadequate and unplanned infrastructure, exhibition style, service provided, and supportive attitude. This article aims to create a service quality measurement database for museums, enhancing their service quality and promoting sustainable tourism. The increased visitor numbers will boost local communities' income, contribute to the country's Sustainable Development goal 8, and protect local culture.
JASBH, Vol. 69(2), 2024, pp. 259-280
Melangkaui batasan: analisis strategik score dalam membangunkan kompetensi global guru di Malaysia [Beyond the boundaries: score strategic analysis in developing the global competence of teachers in Malaysia]
Authors: Ibrahim Siti Nurul Aqiedah , Mohd Matore Mohd Effendi Ewan , Engku Ismail Engku Mohd Sharul Akimi , Abdul Hadi Adila Athirah
Published: January 2025

A highly globally competent teacher can nurture and shape students with noble values, appreciate and be open to cultural diversity, understand multiple perspectives, and be able to communicate and collaborate with individuals from different backgrounds to ensure global sustainability. Discussions on global competency using SCORE analysis are rarely held. Therefore, this concept paper aims to discuss strategy-based assessment in developing teachers' global competency in Malaysia using the SCORE analysis, which includes the elements of Strength, Challenges, Options, Responses, and Effectiveness. The study results show that teachers' global competency development has high potential if effective strategies are properly organized. The benefits extend beyond the country's education sector, positively impacting stakeholders and external parties due to its significant business value. The limitations of this concept paper can be addressed by using other models such as SWOT, NOISE, or SOAR as analysis models. This concept paper implies that it enriches the literature by offering a systematic analytical framework to evaluate and enhance global competency in education, adds a strategic dimension to research on teachers' global competency, helps to understand how teachers can build capacity more structurally and focused, and provides clear guidance for teachers and administrators in identifying strengths, addressing challenges, and implementing effective actions to enhance the effectiveness of education programs in schools. A recommendation for future research is to evaluate how strategic approaches such as SCORE help teachers identify strengths and challenges in global education, explore action options, and assess their effectiveness in enhancing global competency.
Bimbingan instruksional meningkatkan kualiti pengajaran dan pembelajaran [Instructional coaching enhance quality of teaching and learning]
Authors: Md Saman Anita , Shafie Sharifah , Saad Asma , Hashim Zuhailah
Published: January 2025

The teaching profession demands that teachers master PAK-21 techniques and skills in building and forming concrete student knowledge. Through this PAK-21 practice, the development of students' potential is honed holistically in producing knowledgeable and competitive human capital at the global level. This can only be generated through an effective and quality teaching process. However, empirical evidence shows that the quality of teaching and learning (TnL) of teachers is still at a moderate level which is at a satisfactory level. Therefore, this study was conducted to identify the extent to which the quality of teacher teaching can be improved through instructional coaching by School Improvement Specialist Coaches Plus (SISC+). This study involved 46 samples consisting of committee leaders and senior teachers known as middle leader teachers (MLT) in the state of Kedah. The survey was conducted online. The results of descriptive analysis using SPSS version 28 software show that the level of SISC+ personnel instructional coaching practice and the effectiveness of SISC+ personnel instructional coaching on the quality of MLT teaching and learning is very high. This finding indirectly shows that SISC+ personnel instructional coaching is very relevant in improving the quality of TnL MLT in preparing them as TnL leaders in schools. In conclusion, the results of this study are new empirical evidence that the presence of SISC+ personnel has a positive impact on the education arena in this country.
Lähijohtamisen kokemustiedon arvo Lapin matkailuelinkeinolle
Authors: Kaihua Heidi , Pietiläinen Ville
Published: January 2025

Matkailualaan keskittyvän johtamistutkimuksen painopiste on usein alan työntekijöiden, toimintaympäristön tai reunaehtojen tarkastelussa, jolloin johtamisen tavoittaminen erilaisiin tilanteisiin sidonnaisena, kokemuksellisena ilmiönä jää vähäiselle huomiolle. Tässä tutkimuksessa oletamme, että matkailualan houkuttelevuustekijät ja kehitysmahdollisuudet kiteytyvät monilta osin johtamistaitoihin, sillä alaan liittyvät haasteet ovat luonteeltaan jatkuvia, eikä niihin ole odotettavissa yhtä ratkaisua lähitulevaisuudessa. Tutkimuksessa tarkastelemme millaista arvoa lähijohtamisen kokemuksellinen näkökulma tuo Lapin matkailuyritysten haasteiden ymmärtämiselle ja ratkaisemiselle. Kokemuksellisen suhteen ymmärtämiseksi olemme valinneet tutkimukseen fenomenologisen lähestymistavan.Tutkimuksen aineisto muodostuu 15 matkailu- ja sen tukipalveluihin lukeutuvien yritysten lähijohtajien yksilöllisiin kokemuksiin perustuvista kirjoitelmista, jotka on kerätty vuonna 2022. Olemme valinneet tutkimuksen lähestymistavaksi tulkitsevan fenomenologisen analyysin (IPA, interpretative phenomenological analysis, Smith ym., 2022). Tutkimuksen tuloksena esitämme neljä ryhmäteemaa, jotka ilmentävät lähijohtamisen suhdetta elinkeinon kohtaamiin haasteisiin 1) epävarmuutena, 2) sopeutumisena, 3) kehittymisenä ja 4) ratkaisemisena. Tulokset täydentävät matkailualan tutkimuskirjallisuutta johtamisdynamiikan ymmärryksellä, tuoden esiin arjen lähijohtamista tilannekohtaisesti rakentuvana ilmiönä. Tuloksia voidaan hyödyntää Lapin matkailuyrittäjien tukemisessa, mutta myös lähijohtamisen kehittämisessä.
NAVIGATING ENGLISH READING COMPREHENSION: THE ROLE OF STUDENTS' SELF-REGULATION
Authors: Ningsih Wirda , Zalisman Zalisman
Published: January 2025

This study aims to explore the role of student self-regulation in understanding English reading at Danul Hikmah Pekanbaru MTS. Using a quantitative research design with a correlational descriptive approach, the study involved 46 students selected through stratified random sampling techniques out of a total population of 143 students. The research instruments included a questionnaire to measure self-regulation and standard tests to measured reading understanding. The data collection process begins with validity and reliability testing of instruments through pretests, followed by primary data collection. The data analysis was performed using SPSS version 25, using descriptive statistics to summarize data and Pearson correlations to test the relationship between self-regulation and reading understanding. The results of the analysis showed a significant positive correlation between student self-regulation and their English reading understanding score. The Pearson Correlation Coefficient of 0.849 indicates a strong relationship, where a higher level of self-Regulation is associated with a better understanding of reading. These results emphasize the importance of developing self-regulation skills in students to improve their academic performance in reading. Therefore, teaching strategies that facilitate the development of self-regulation can make a positive contribution to learning outcomes. These findings recommend the application of educational interventions that focus on the development of self-regulation to improve student reading understanding and, ultimately, their overall academic performance.
Implementasi Pendidikan Karakter Disiplin Siswa Kelas III SD Muhammadiyah 11 Randegan, Tanggulangin, Sidoarjo
Authors: Sari Rahma Della , Indrakurnawan Machful , Sari Nila Kartika
Published: January 2025

This study aims to describe the implementation of disciplinary character education for third grade students of Muhammadiyah 11 Randegan Elementary School, Tanggulangin, Sidoarjo. The method used in this research is qualitative research with descriptive type. Data collection techniques used in this study are observation, interviews and documentation. The data sources obtained in this study came from homeroom teachers and third grade students. Data analysis was obtained using the miles and Huberman analysis technique, namely data reduction, data presentation and data conclusion. The results of this study indicate that third grade students of SD Muhammadiyah 11 Randegan can implement disciplinary character education well based on discipline indicators, namely getting used to coming and leaving school on time, orderly marching when entering class, following literacy activities in an orderly manner, obeying the rules that apply in class, wearing school uniforms according to schedule, completing assignments on time, following learning in an orderly manner, performing dhuha and dzhuhur prayers in congregation.
V. Sukhomlynskyi State Scientific and Educational Library of Ukraine (2020-2024): Works, Electronic Resources: scientific and auxiliary bibliographic index
Authors:   V. Sukhomlynskyi State Scientific and Educational Library of Ukraine
Published: January 2025

The bibliographic index presents the achievements (scientific works, electronic resources) of the scientific and librarians of the V. Sukhomlynskyi State Scientific and Educational Library of Ukraine for five years of activity (2020-2024). The publication is addressed to scientific, scientific- pedagogical, pedagogical, library workers, students, information service workers.
“Shroud of Turin” and “Blood of Saint Januarius”: Two Relics Compared
Authors:   University of Messina. Department of Mathematical and Computer Sciences, Physics Sciences and Heath Sciences. Viale Ferdinando Stagno d’Alcontres 31, I-98166 Messina, Italy, Giovanni Fazio , Francesca Riotto ,   Diocese of Oppido Mamertina-Palmi. Via Rocco Pugliese 38, I-89015 Reggio Calabria, Italy.
Published: January 2025

In this paper, we aim to compare the investigations of Blood found on the Shroud of Turin and the Blood
of Saint Januarius. Analysis of the first relic reveals the presence of whole blood with bile pigments. In
fact, fibrils covered in blood and serum albumin were also extracted from the burial linen. For the latter
relic, the situation remains uncertain, as the Roman Catholic Church does not allow sampling. This is
puzzling, given that the blood of Jesus, which is present on the Shroud, has already been investigated.
Why should it not be possible to investigate the blood of Saint Januarius? Only the Ecclesiastical
Authorities can provide an answer. We hope it will be the right one.
Recurrence in Sraffa’s Standard Commodity
Authors:   IRCrES – CNR, Mario De Marchi
Published: January 2025

A suggestion is made here for partially correcting one flaw commonly attributed to the economic thought
of Smith. Overcoming this problem may perhaps pave a new way to define Sraffa’s Standard Commodity
The Role of Gut Microbiota in Tumor Recurrence and Therapy Resistance in Colorectal Cancer: Molecular Mechanisms and Clinical Implications
Authors:   Institute of Teaching, Research, and Innovation, Liga Contra o Câncer, Natal, Brazil, Amália Cinthia Meneses do Rêgo ,   Full Professor, Postgraduate Program in Biotechnology, Potiguar University, Potiguar University (UnP), Natal/RN, Brazil., Araújo-Filho Irami ,   Institute of Teaching, Research, and Innovation, Liga Contra o Câncer, Natal, Brazil,   Full Professor, Postgraduate Program in Biotechnology, Potiguar University, Potiguar University (UnP), Natal/RN, Brazil.,   Full Professor, Department of Surgery, Potiguar University, Natal/RN, Brazil.
Published: January 2025

Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide.
Emerging evidence underscores the pivotal role of gut microbiota in influencing CRC initiation,
progression, recurrence, and resistance to therapies. This review delves into the complex interactions
between gut microbiota and CRC, highlighting the differential microbial profiles in healthy individuals,
early-stage CRC, advanced CRC, and recurrent disease. The functional impact of key microbial species,
such as Fusobacterium nucleatum and Bacteroides fragilis, is explored, emphasizing their roles in
promoting chronic inflammation, genomic instability, and tumor microenvironment remodeling. The
review examines microbiota's metabolic and immunological pathways, including SCFAs, secondary
bile acids, and cytokine networks, which collectively shape tumor behavior and therapeutic outcomes.
Special attention is given to the influence of microbiota on therapy resistance, including chemotherapy,
immunotherapy, and targeted therapies, as well as its role in creating permissive niches for tumor
recurrence and metastasis, particularly in the liver. The potential of microbiota-targeted interventions,
such as probiotics, prebiotics, and fecal microbiota transplantation, is critically assessed as emerging
strategies to improve clinical outcomes. The review also identifies significant research gaps, including
the temporal dynamics of microbiota during CRC progression, the relationship between microbiota
and molecular subtypes of CRC, and the impact of lifestyle and dietary interventions on microbial
composition. This comprehensive synthesis underscores the clinical implications of integrating
microbiota-modulating strategies into CRC management and provides a roadmap for future research to
leverage microbiota for personalized oncology
CODE SWITCHING IN NATURALIZED INDONESIAN FOOTBALL PLAYER’S INSTAGRAM CAPTION
Authors: Nasution Atikah Auni , Silvizi Hijra Hannah Zakiyya , Fianda Afiqah , Sianturi Naomi Elisabeth , Rangkuti Rahmadsyah
Published: January 2025

This research investigates the phenomenon of code-switching in naturalized Indonesian football players' Instagram captions, with a particular focus on how audience perceptions are affected. This research used Poplack's code-switching theory (1980) to analyze Instagram captions. This research used qualitative method to collect data from 2024 Instagram posts of naturalized football players. The research results show that 43 code-switching was found in naturalized Indonesian football players' Instagram captions. 21% are intra-sentential switching, and 79% are inter-sentential switching. Meanwhile, no tag switching is identified. A number of code-switching are dominated by inter-sentential code-switching. The 70 comments received from the audience were overwhelmingly positive, with 93% of respondents praising and supporting the players' adaptation to Indonesian culture. In conclusion, this research highlights the frequent use of code-switching in Instagram captions by naturalized Indonesian football players. This enables players to communicate more effectively and represent their diverse backgrounds, which positively shapes audience perception.
Legal principles of interpretation of international conventions on avoidance of double taxation
Authors: Timchenko L. D. , Kononenko V. P.
Published: January 2025

The legal principles of interpretation determine the basic principles by which the content and means of application of legal norms are determined. They are defined as general principles and methods used in the interpretation of legal acts to determine their true meaning and apply them to specific situations.
The article examines the problems of interpretation of the conventions of Ukraine on the avoidance of double taxation, analyzes the legal basis of their interpretation. In particular, the emphasis is placed on the key aspects of the process of interpretation of such conventions in order to ensure their effectiveness and proper implementation. Analysis of legal grounds related to the issue of interpretation of international treaties is important for understanding and improving the regulatory environment and rule-making activities in the field of taxation. The analysis was made in the context of the national legislation and taking into account international experience.
It was concluded that the interpretation of international conventions on the avoidance of double taxation requires a complex approach. This approach should take into account international norms and national legislation of each of the parties to the contract. When interpreting the texts of conventions, it is important to take into account not only the letter of the law, but also its spirit, the will of the parties, the historical context of the conclusion and international practice. Issues of interpretation of terms and concepts in international conventions on the avoidance of double taxation require careful analysis. Such an analysis is made taking into account the meaning of such treaties in the context of the tax system of each participating state. The application of conventions on the avoidance of double taxation contributes to the creation of a favorable environment for international business, contributes to the economic growth and development of states.
International double taxation agreements can have other important benefits. Among such advantages are the reduction of administrative and legal costs for enterprises, the stimulation of international trade and the promotion of economic relations between states. Thus, while the agreements themselves may not have a significant impact on investment flows, they are important in creating a favorable business environment and reducing tax risks.
Rule-making of public authorities and positive law (theoretical aspects of interaction)
Authors: Lutskiy R. P.
Published: January 2025

The article focuses on the essence of rulemaking powers of public authorities, the limits of executive independence in the exercise of its rulemaking powers, the difference between the concept of «executive independence in relation to other branches of government» and the concept of «operational independence of individual subdivisions of executive authorities», as well as their relationship with rulemaking.
The rule-making powers of public authorities are used to realize the state’s goals, objectives and functions. That is why it is important to clarify their essence and requirements for their implementation. Legal science is faced with the question of the relationship between rulemaking powers and rulemaking activities, as well as the need for appropriate legal procedures for rulemaking activities. There is a need for an in-depth understanding of the need to vest executive authorities with discretionary powers for better management, and the need to control the exercise of discretionary powers.
On the basis of the understanding of the rule-making powers of executive bodies as the powers to establish, change and cancel mandatory rules in the form of issuing bylaws, the conclusion that the rule-making powers of executive bodies are inseparable from their legal status is substantiated, the issue of their appointment as a means of implementation is considered by executive power bodies of their functions, tasks and powers, as well as the need for general control over the exercise of rule-making powers by executive power bodies from the legislative power. The question of the use of discretionary powers by the executive authorities is considered, as their powers to act at their own discretion, choosing from among several prescribed legal options for behavior the one that best meets the needs of achieving the management goal.
The conclusion that the rule-making powers of executive authorities serve as the legal basis for rule-making activity and are carried out through rule-making activity is substantiated. By virtue of their importance and impact on social relations, on the rights and obligations of individuals, rule-making powers require the implementation of rule-making activities of executive authorities in a special legal procedural form, since for their rule-making activities it is important and necessary to observe the appropriate method, order and procedures of implementation, while observing the limits of competence.
The need for regulatory regulation of the procedure for the implementation of rule-making activities of executive authorities, its high level of formalization, recording of its results, as an activity that is important for keeping executive authorities within their powers, observing the principle of the rule of law, protecting the rights and freedoms of the individual, is substantiated.
Juridical-technological dimension of law-making as a prospective direction of its scientific research
Authors: Didych T. О.
Published: January 2025

In the article, the author focuses on the expediency of changing the methodological basis of the scientific study of the phenomenon of law-making. It is emphasized that today in legal literature, as a result of the active development of scientific studies of law-making, various approaches to its understanding have developed, which causes not only an increase in the pluralization of its understanding, but is also marked by the ambiguity of its perception and inconsistency of knowledge. It is worth noting that the basis of successful legal research activity is primarily methodological approaches that allow developing a strategy for scientific knowledge of the studied legal phenomenon or process, based on the prevailing perception of it. Such an approach is the most optimal in conditions of multifaceted approaches to understanding the phenomenon or process under investigation. Therefore, the knowledge of law-making as a multifaceted phenomenon, which in legal science is represented by various approaches to understanding, today requires the development of a coherent methodological basis, ensuring a complex integrative approach to its knowledge. An important and functionally demanding modern approach to the knowledge of the phenomena of legal reality, especially those whose content is legal practical activity, is the legal- technological dimension. It is proven that thanks to it, the relevant legal phenomena and processes can be perceived and characterized from the point of view of a special technological mechanism where various components interact, providing algorithmization of the relevant legal practical activity.
Based on the finding of doctrinal approaches to the understanding of legal technologies from the point of view of their methodological significance, it was concluded that the technological vector of knowledge of law-making as a multifaceted phenomenon has a significant cognitive potential, providing appropriate perception and further knowledge of it. It was noted that it will allow: 1) to strengthen historical-legal and comparative-legal studies oflaw-making; 2) to optimize the methodological provision of scientific knowledge of law-making through the prism of a complex of relevant legal technologies; 3) focus attention on the legal provision of law-making, both at the international legal and national level; 4) to improve the conceptual and categorical legal apparatus of science and the science of legal theory; 5) to strengthen the research of individual varieties of law-making, laying the basis of their separation, including legal-technological features of law-making, etc.
Regulatory activity: essential characteristics in new realities
Authors: Onishchenko N. M.
Published: January 2025

The article examines the essential characteristics of norm-designing activity in the context of modern challenges and priorities, which is analyzed taking into account instrumental and substantive typological elements. It is this approach, taking into account instrumental practices and essential characteristics, that might be useful when considering the issues of adapting the legislation of Ukraine to the legislation of the European Union. Applied illustrations of norm-designing activities in foreign countries are provided. A conclusion is made regarding the need to involve in such activities both representatives of legal doctrine and representatives of legal practice. Certain attempts in this regard have repeatedly arisen in various state institutions, in particular in the Ministry of Justice of Ukraine. However, today there is an urgent need to create a single Center for planning and studying normative design activities, which was repeatedly discussed even before the full-scale invasion of the russian federation into Ukraine. And that extremely strengthens this necessity (regarding norm-designing activity) today.

It is somewhat more difficult to study the issue, which is related to the essential substantive aspect of normative design activity and is supported by illustrative conclusions in the context of veteran policy and the forms of its implementation. Veteran policy is usually considered in the context of the integration of veterans into civilian life. However, we understand today that after the Victory, a twofold process will take place: society will integrate veterans, and veterans will adapt society to life in new conditions and realities, taking into account the proximity of the state – sponsors of terrorism. In addition, the level of «non-legal consciousness» and «non-legal culture» existing in the Russian Federation deserves special attention in this context. It is clear that it is impossible to influence these processes in one day, one week, not even one year. Therefore, it is the systematic work, which will consist of appropriate educational practices, starting from schools, institutions of higher education, enterprises, organizations, etc., that can be organized by veterans, their representatives, and veteran centers. It is emphasized that such experience does not exist in world realities and practices. We are talking about creating a system of effective control over the state’s performance of its duties.

It is emphasized that normative design work at all levels should ensure human rights and freedoms, in particular by studying the best practices of the world level, and developing and providing perfect normative forms of the new experience of legal development in Ukraine.
Law as a Subject of Theoretical and Methodological Research (Modern Concepts)
Authors: Kubko Ie. B.
Published: January 2025

The article examines modern concepts of understanding law as a subject of theoretical and methodological research, which makes it possible to define their main characteristics in general terms. The article looks into the main theoretical and methodological approaches in contemporary legal thought, based on the understanding of law, its nature, and essence in various historical periods, and taking into account contemporary influences on legal concepts, their simultaneous stability, and flexibility. Legal concepts that exist within the framework of scientific discussions and their practical use are considered in terms of their perception by legal and, in particular, judicial practice. It is a judicial practice related to law-making that provides the environment facilitating the development of the latest legal ideas and more or less established concepts of the essence of modern law. Unfortunately, for a long time, legal science in Ukraine did not have the opportunity to develop alongside the generally accepted areas of legal theory and was affected by the influence of numerous ideological factors. The national legal science of Ukraine is actively removing the negative theoretical constructs of the past. At the same time, relying on the current national theoretical achievements and legal realities, it is trying to understand and, to a certain extent, adapt to the latest conceptual legal ideas, the main directions of which are highlighted in the article. The article examines the primary scientific concepts that are currently being debated globally and are actively embraced by legal practitioners. A particular emphasis is given to the scientific research conducted by American scholars, with the objective of highlighting contemporary legal procedures and occupying leading positions in their theoretical comprehension, at the level of the most recent legal concepts. The article examines the theories of textualism, originalism, the concept of real law, intentionalism, and purposivism in general. The impact of artificial intelligence on both legal reality and legal research is brought to the fore. The purpose of the article is to reveal the essence of the main theories of law which arise as a result of the US judicial practice and are transformed into the global theory of jurisprudence.
PELABUHAN KASIPUTE DAN DAMPAKNYA BAGI KEHIDUPAN EKONOMI MASYARAKAT DI KELURAHAN KASIPUTE KECAMATAN RUMBIA KABUPATEN BOMBANA: 2003-2020
Authors: Azisa Nur , Ahmad Ahmad , Suddin Suharni , Wardani Ajeng Kusuma
Published: January 2025

Artikel ini bertujuan untuk menjelaskan perkembangan dan dampak Pelabuhan Kasipute bagi kehidupan ekonomi masyarakat di Kelurahan Kasipute Kecamatan Rumbia Kabupaten Bombana 2003-2020. Penelitian ini menggunakan metode sejarah yang terdiri dari lima tahapan kerja, yaitu sebagai berikut: pertama, pemilikan topik, kedua, heuristik atau pengumpulan sumber, ketiga kritik sumber, keempat interpretasi sumber, dan kelima yaitu historiografi. Hasil penelitian ini menunjukkan bahwa Pelabuhan Kasipute yang berdiri tahun 1969 memiliki peranan penting dalam mendukung aktivitas masyarakat di bidang kepelabuhanan dan bidang transportasi angkatan laut. Pembangunan pelabuhan kasipute memberikan dampak bagi masyarakat sekitar, di antaranya dapat menyerap tenaga kerja seperti buruh kapal, tukang ojek, dan pedagang-pedagang di sekitar pelabuhan. Pelabuhan Kasipute juga menjadi fasilitas penunjang dalam mendukung mobilitas atau perpindahan orang atau penumpang ke daerah lain, memperlancar arus barang dan hasil-hasil pertanian.  Pelabuhan Kasipute Kabupaten Bombana pada tahun 2003-2020 mengalami perkembangan yang pesat sejalan dengan perkembangan zaman, ditandai dengan derasnya arus penumpang dan barang serta fasilitas memadai. Hal tersebut ditandai dengan adanya fasilitas-fasilitas pendukung berupa area tambat, daya listrik/lampu sebanyak 12 titik, pos portal/PAD, dan terminal mobil penumpang.
BENTUK DAN MAKNA SIMBOLIK SULAPA’ EPPA’ SEBAGAI FALSAFAH HIDUP SUKU BUGIS-MAKASSAR
Authors: Jusmiati Jusmiati
Published: January 2025

Sulapa’ Eppa’ yang merupakan falsafah hidup masyarakat suku Bugis-Makassar memiliki bentuk dan makna simbolik. Ada tiga tujuan dalam penelitian ini yaitu untuk menguraikan sejarah, bentuk, dan eksistensi Sulapa’ Eppa’. Penelitian ini menggunakan jenis penelitian kepustakaan dengan pendekatan historis dan sosiologi. Langkah-langkah dalam penelitian ini yaitu heuristik, kritik sumber, interpretasi dan historiografi. Hasil penelitian ini yaitu, Pertama, sejarah Sulapa’ Eppa’ bermula dari sebuah bentuk kepercayaan masyarakat berupa simbol alam semesta berupa angin, api, air, dan tanah yang dianggap sebagai sebuah unsur kesempurnaan. Kedua, bentuk dan makna Sulapa’ Eppa’ berasal dari walasuji sebagai tempat ditemukannya, selanjutnya digambarkan juga ke dalam huruf aksara lontara’ “sa”. Selain itu, Sulapa’ Eppa’ dapat digambarkan melalui: kosmogini (angin, api, air, dan tanah), susunan alam semesta (langit, dunia, dan dunia bawah) dan konsep manusia (tau). Ketiga, eksistensi Sulapa’ Eppa’ dalam tatanan kehidupan masyarakat suku Bugis-Makassar masih bisa ditemukan pada upacara pernikahan, pakaian adat, tempat tinggal dan berbagai bentuk kehidupan lainnya. Sulapa’ Eppa’ yaitu sebuah falsafah hidup yang menunjukkan karakter masyarakat Bugis-Makassar yang bukan hanya sekedar gagasan semata tetapi memiliki makna yang mendalam. Adapun urgensi penelitian ini terlihat dalam pengadaptasian bentuk falsafah Sulapa’ Eppa’ yang diharapkan agar nilai-nilai sejarah dan budaya lokal tetap lestari di era globalisasi saat ini.
IDENTIFIKASI SUMUR TUA PENINGGALAN JEPANG 1942-1945 DI KELURAHAN KANDAI KOTA KENDARI SULAWESI TENGGARA
Authors: Sarman  , Aslim  , Aswati  , Sudu La
Published: January 2025

This research aims to identify old wells from the Japanese occupation period. To achieve this goal, the study employs a qualitative research method. Data collection was conducted through literature review, interviews, observations, and analysis. The findings indicate that the old well located in Kandai Subdistrict is a remnant from the Japanese occupation during 1942-1945. Surrounding the well, there are other remnants related to Japanese defense efforts, such as bunkers and pillboxes of various sizes situated right in front of the well. Researchers identified three old wells, generally located at the base of hills or mountains. These wells have undergone changes in form due to activities and their use as a clean water source for the residents of Kandai Subdistrict, Kendari City. The old Japanese wells are still utilized by the community, serving hundreds of residents in several neighborhood areas (RT). The uniqueness of these wells lies in their ability to never run dry, even during the dry season, which allowed them to supply water to Japanese soldiers in the past and continues to serve the local population today.
Keywords: Japanese left; Old Well; Functions and Utilization
INTERAKSI SOSIAL ANTARETNIS DI DESA PUUPI KECAMATAN KOLONO KABUPATEN KONAWE SELATAN 1980-2022
Authors: Al Kausar Muhamad , Jepitrawati Jepitrawati , Hamuni Hamuni , Burhan Faika
Published: January 2025

Penelitian ini bertujuan untuk menjelaskan interaksi sosial antaretnis di Desa Puupi Kecamatan Kolono Kabupaten Konawe Selatan. Jenis penelitian ini merupakan sejarah sosial dengan menggunakan pendekatan multidimensional. Data primer dari penelitian ini berupa keterangan-keterangan yang peneliti dapatkan dari informan yang merupakan pelaku sejarah atau saksi mata mengenai penelitian terkait. Metode yang digunakan dalam penelitian ini adalah metode sejarah menurut Kuntowijoyo (2013: 69-81) yang terdiri dari lima tahap yaitu pemilihan topik, pengumpulan sumber, verifikasi sumber, interpretasi sumber, dan historigrafi. Hasil penelitian ini menunjukkan bahwa sejumlah etnis dari berbagai wilayah memilih Desa Puupi sebagai tempat berdomisili karena wilayah Desa Puupi strategis. Wilayah Desa Puupi terdiri atas lautan dan daratan sehingga memudahkan masyarakat mencari nafkah untuk menunjang kehidupan ekonomi. Tahap-tahap interaksi antaretnis terdiri atas: kerjasama, akomodasi, asimilasi, akulturasi, persaingan, konflik. Proses interaksi sosial di Desa Puupi terbagi dalam tiga tahap periode yaitu periode 1980-1990, periode 1991-2001 dan periode 2002-2022. Faktor-faktor yang memengaruhi interaksi sosial antaretnis di Desa Puupi Kecamatan Kolono yaitu komunikasi dan solidaritas.