bluuebunny/crossref_metadata_2025 huggingface dataset:
PROSTHODONTIC MANAGEMENT OF RARE ODONTOGENIC TUMOR (PINDBORG TUMOR) WITH IMPLANT RETAINED MANDIBULAR OVERDENTURE
Authors: Ali Buzayan Muaiyed Mahmoud , Lim Ghee Seong , Elkezza Aeman , Take Yeoh Oon
Published: March 2024

Pindborg tumour or calcifying epithelial odontogenic tumour (CEOT) is a rare, slow-growing benign tumour occurring most frequently in the posterior part of the mandibular arch. Management ranges from simple enucleation to a segmental resection of the mandible. The latter compromises the jaw foundation for any future prosthetic rehabilitation and warrants jaw reconstruction procedures to improve the retention and stability of the prosthesis. Using mini-implants in such compromised situations is a minimally invasive and cost-effective aid compared to conventional implants. The present case report documents the prosthetic rehabilitation of a patient who underwent mandibular resection for a Pindborg tumour using mini-implants.
miR-155 EXPRESSION UTILIZATION AS A POTENTIAL DIAGNOSTIC BIOMARKER OF HEART FAILURE: A SYSTEMATIC REVIEW
Authors: Tandarto Kevin , Tjendrawinata Ivander , Sukmadi Norman , Laksono Sidhi
Published: March 2024

Background: Heart failure (HF) is a complex clinical syndrome with signs and symptoms resulting from any structural dysfunction of ventricular filling or blood ejection. miRNAs were known as essential regulators and tissue-specifically expressed. MicroRNA-155 (miR-155) expression in macrophages is already well known to promote hypertrophy, cardiac inflammation, and failure due to pressure overload. In this study, we aim to identify the role of expression miR-155 as a potential biomarker for HF.
A CASE OF NECROPSOBACTER ROSORUM BACTERAEMIA
Authors: Pirathaba Karshini Jeya , Ishak Nurhafizah , Hafiz Ngoo Siti Khairani Mohd , Hashim Rohaidah , Samsudin Nazirah
Published: March 2024

Necropsobacter rosorum (N. rosorum) is a gram-negative organism previously classified under the family Pasteurellaceae. It has been isolated from the gastrointestinal and respiratory tracts of mammals. On the other hand, there is very little information available about how N. rosorum infects human. Due to a paucity of information in the database, commercial identification methods such as VITEK identification system or Analytical Profile Index (API) frequently misidentify this organism. Thus, it is a challenge for laboratories to accurately identify N. rosorum. By using matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF), we were able to identify N. rosorum in a patient with sepsis secondary to wet gangrene of the left big toe. This case report aims to shed light on the application of advance diagnostic tests for the early detection of human pathogens.
DEVELOPMENT OF A COGNITIVE THERAPY MODULE TO ENHANCE SELF-ESTEEM FOR YOUTH WITH PHYSICAL DISABILITIES IN MALAYSIA
Authors: Mohd Jaladin Rafidah Aga , Fernandez Janet Ann , Muhamad Ahmad Shamsuri , Mohammad Roose Aina Razlin , Sipon Sapora
Published: March 2024

Youth with physical disabilities may have concerns about their bodily functions and appearance, which do not typically conform to sociocultural norms. A mounting body of research confirmed that physical disability has an adverse impact on self-esteem development. This study aimed at developing a cognitive therapy module for professional counsellors to help Malaysian youth with physical disabilities enhance their self-esteem. The methodology comprised three stages: (i) self-esteem baseline assessment; (ii) module design and development; and (iii) module evaluation. First, the Rosenberg Self-Esteem Scale was used to collect data from 110 youth with physical disabilities. The results revealed that participants had moderate levels of self-esteem (mean, x̄ = 30.16). This finding highlighted the need to increase the level of self-esteem among youth with physical disabilities. The second stage involved the development of the cognitive therapy module for self-esteem enhancement (CTSEE) using Sidek’s model of module development, which resembles the ADDIE framework. The third stage involved evaluating the module’s content validity and reliability. Findings showed that the therapy module has high content validity and reliability. The overall findings demonstrate that the CTSEE module can be applied by professional counsellors to enhance self-esteem among youth with physical disabilities.
Emerging Adults’ Views of Marriage: Influence of Religion and Sexual History
Authors: Herweyer Julie , Brushaber-Drockton Katherine , Searight H. Russell
Published: March 2024

Historically, religion has had a significant influence on mating strategies. As current trends show a shift away from social institutions as the guiding constructs for value formation, the role of religiosity as a moderator for perceptions of marriage, premarital sexual activity, and cohabitation outside of marriage needs to be revisited. The current study examines the association of religiosity, as assessed with the Duke University Religion Index (DUREL), and attitudes toward marriage, the perceived ideal age to marry, and sexual activity. All three dimensions of the DUREL (Organized Religious Activity, Non-Organized (Informal) Religious Activity, and Intrinsic Spirituality) were associated with more positive attitudes toward marriage. Participation in organized religious activity was associated with a later age for beginning sexual activity and fewer sexual partners.
JN1 Variant Sparks Concern: Time for Urgent Action!
Authors: Rizwan Ali Abdullah , Sohail Anusha
Published: March 2024

The JN1 variant harbors Leu455Ser and three mutations in non-spike
proteins contributing to increased transmissibility and immune escape
ability. Pseudovirus assays have shown that the infectivity of JN.1 is
significantly higher than its predecessor XBB.1.5 from omicron family
(1). JN.1 is about 3 to 5 times less susceptible to neutralizing
antibodies than the XBB.1.5 variant that is in the updated booster
raising concerns about its potential impact on public health (2)
Calibration design for pharmaceutical bioprocesses: A novel approach for knowledge transfer in Design of Experiments
Authors: Helleckes Laura Marie , Wirnsperger Claus , Polak Jakub , Gosalbez Gonzalo Guillén , Butté Alessandro , Stosch Moritz von
Published: March 2024

Modern machine learning methods, and their use alongside established
paradigms such as Quality by Design, have the potential to fundamentally
change the way bioprocesses are developed. In particular, horizontal
knowledge transfer methods, which seek to exploit data from historical
processes to facilitate process development for a new product, provide
an opportunity to rethink process development workflows. In this work,
we firstly assess the potential of two knowledge transfer approaches,
meta learning and one-hot encoding, in combination with Gaussian process
(GP) models. We compare their performance to GPs developed only on data
of the new process. Using simulated mammalian cell cultivation data, we
observe that both knowledge transfer approaches outperform the
individual-product approach. In the second part, we address the question
whether experiments for a new product could be designed more effectively
by exploiting existing knowledge. In particular, we suggest to
specifically design few runs for the novel product to calibrate
knowledge transfer models, a task that we coin calibration design. We
propose a novel, customised metric to identify a set of calibration
design runs, which exploits differences in process evolutions of
historical products. In two simulated case studies, we observed that
training with calibration designs yields similar test set errors
compared to common approaches of Design of Experiments. However, much
fewer experiments are needed for the former, suggesting an interesting
alternative for future bioprocess development. Overall, the results
suggest that process development could be significantly streamlined when
systematically carrying knowledge from one product to the next.
Karst water resources in a changing world: Review of solute transport modelling approaches
Authors: Çallı Kübra Özdemir , Chiogna Gabriele , Bittner Daniel , Sivelle Vianney , Labat David , Richieri Beatrice , ÇALLI Süleyman Selim , Hartmann Andreas
Published: March 2024

Karst water resources are valuable freshwater sources for around 10 %
of the world population. Nonetheless, anthropogenic factors and global
changes have been seriously deteriorating the karst water quality and
dependent ecosystems. Solute transport models are powerful tools to
monitor, control, and manage the water quality and dependent ecosystem
functioning. By representing and predicting the spatiotemporal behavior
of solute migration in karst systems, the transport models enhance our
understanding about the karst transport processes, thus enabling us to
explore contamination risks and potential outcomes. This paper reviews
the current state of knowledge on the modelling of solute transport
processes in karst aquifers, thereby unveiling the fundamental
challenges underlying a successful karst transport modelling. We discuss
to what extent and in what ways we can handle these challenges and
derive the key challenges and directions for reliable modelling of
transport processes in karst systems in the present context of global
changes.
Energy and exergy diagnostics of an industrial annular shaft limekiln working with producer gas as renewable biofuel
Authors: Camargos Tomás Pessoa , da Costa Andréa Oliveira , Costa Junior Esly
Published: March 2024

Quicklime, a globally significant commodity used in various industrial
applications, is produced in limekilns requiring substantial energy,
traditionally, from fossil fuels. However, due to escalating emission
constraints and depletion of fossil fuel deposits, the quicklime industry
explores alternative fuels, like biomass. The literature lacks feasibility
diagnostic studies on limekilns using alternative biomass fuels. Thus, this
article aims to conduct energy and exergy diagnostics on an industrial
limekiln using producer gas derived from eucalyptus wood as renewable
biofuel. Employing industrial data and thermodynamics principles, the
equipment was characterized, and results were compared with literature
findings for similar limekilns using fossil fuels. The Specific Energy
Consumption (??????) for the producer gas-operated limekiln was 4.8
GJ/tquicklime, with energy (??????) and exergy (??????) efficiencies of
54.6% and 42.2%. Overall energy (?????????????????????) and exergy
(?????????????????????) efficiencies were 42.0% and 23.6%, respectively,
lower than literature values. ???????????????????? was 7.6 GJ/tquicklime,
higher than literature results. Identified enhancements for both renewable
and fossil fuel-powered limekilns involve recovering energy and exergy,
including heat recovery from exhaust gases, minimizing thermal losses, and
optimizing operational variables. These findings offer valuable insights for
researchers exploring renewable biofuel adoption, like producer gas derived
from eucalyptus wood, as alternatives to conventional fossil fuels in
limekilns.
A new variant of Jensen inclusion and Hermite-Hadamard type inclusions for interval-valued functions
Authors: Sitthiwirattham Thanin , Sial Ifra , Ali Muhammad , Budak Hüseyin , Reunsumrit Jiraporn
Published: March 2024

In this research, we give a new version of Jensen inclusion for
interval-valued functions, which is called Jensen-Mercer inclusion.
Moreover, we establish some new inclusions of the Hermite-Hadamard-Mercer
type for interval-valued functions. Finally, we give some applications of
newly established inequalities to make them more interesting for the
readers.
The Dunkl-Williams constant related to the singer orthogonality and red isosceles orthogonality in Banach spaces
Authors: Fu Yuankang , Xie Huayou , Li Yongjin
Published: March 2024

In this paper, we shall consider two new constants DWS(X) and DWI(X), which
are the Dunkl-Williams constant related to the Singer orthogonality and
theisosceles orthogonality, respectively. We discuss the relationships
between DWS(X) and some geometric properties of Banach spaces, including
uniform non-squareness, uniform convexity. Furthermore, an equivalent form
of DWS(X) in the symmetric Minkowski planes is given and used to compute the
value of DWS((R2, ???p)), 1 < p < ?, and we also give a characterization of
the Radon plane with affine regular hexagonal unit sphere in terms of
DWS(X). Finally, we establish some estimates for DWI(X) and show that DWI(X)
does not necessarily coincide with DWS(X).
Determining the positive definiteness of even-order weakly symmetric tensors via Brauer-type Z-eigenvalue inclusion sets
Authors: Zangiabadi Mostafa , Tourang Mohsen , Askarizadeh Abbas , He Jun
Published: March 2024

This article presents sufficient conditions for the positive definiteness of
even-order weakly symmetric tensors, based on some new Brauer-type
Z-eigenvalue inclusion sets. In fact, these inclusion sets are obtained
using the partitions of the index set, which improves some of the existing
results.
A classification of cyclic Ricci semi-symmetric hypersurfaces in the complex hyperbolic quadric
Authors: Kim Gyu , Suh Young , Woo Changhwa
Published: March 2024

In this paper, the notion of cyclic Ricci semi-symmetric real hypersurfaces
in the complex hyperbolic quadric Qm* = SO0 2,m/SO2SOm is introduced. Under
the assumption of singular normal vector field N, we have two cases, that
is, normal vector field N is either A-principal or A-isotropic. Even though,
in the case of A-principal, we proved that there does not exist a real
hypersurface in the complex hyperbolic quadric Qm* = SO0 2,m/SO2SOm
satisfying the cyclic Ricci semi-symmetric. But on the other case, we proved
existence of real hypersurfaces with the same condition.
On Gallai’s path decomposition conjecture
Authors: Xie Mengmeng
Published: March 2024

Gallai conjectured that every connected graph on n vertices can be decomposed
into at most n+1/2 paths. Let G be a connected graph on n vertices. The
E-subgraph of G, denoted by F, is the subgraph induced by the vertices of
even degree in G. The maximum degree of G is denoted by ?(G). In 2020,
Botler and Sambinelli verified Gallai?s Conjecture for graphs whose
E-subgraphs F satisfy ?(F) ? 3. If the E-subgraph of G has at most one
vertex with degree greater than 3, Fan, Hou and Zhou verified Gallai?s
Conjecture for G. In this paper, it is proved that if there are two adjacent
vertices x, y ? V(F) such that dF(v) ? 3 for every vertex v ? V(F)\{x, y},
then G has a path-decomposition D1 such that |D1| ? n+1/2 and D1(x) ? 2, and
a path-decomposition D2 such that |D2| ? n+1/2 and D2(y) ? 2.
On symmetrized and Wright convexity
Authors: Moradi Hamid , Furuichi Shigeru , Sababheh Mohammad
Published: March 2024

In this paper, we study symmetrized convex functions and their relations with
other notions of convexity, namely Wright convexity; then, we introduce the
notion of symmetrized log-convexity. Our results include equivalent
statements and extensions of certain existing results in the literature.
Applications that involve Hermite-Hadamard and means? inequalities will be
presented.
Existence and uniqueness of a mild solution for a class of the fractional evolution equation with nonlocal condition involving φ-Riemann Liouville fractional derivative
Authors: Zakaria Mouhssine , Moujahid Abdelaziz , Bouzelmate Arij
Published: March 2024

In this paper, by using the fractional power of operators and theory fixed
point theorems, we discuss Existence and uniqueness of mild solution to
initial value problems for fractional semilinear evolution equations with
compact semigroup in Banach spaces with nonlocal conditions. In particular,
we derive the form of fundamental solution in terms of semigroup induced by
resolvent and ?-Riemann- Liouville fractional derivatives. These results
generalize previous works where the classical Riemann-Liouville fractional
derivative is considered. In the end, we give an example to illustrate the
applications of the abstract results.
Modelling dispersed count data under various shapes of failure rates: A discrete probability analogue of odd Lomax generator
Authors: Eliwa Mohamed , El-Morshedy Mahmoud , Shahen Hend
Published: March 2024

In this article, we introduce a discrete analogue of odd Lomax generator of
distributions. The new discrete class can be utilized as a probabilistic
tool to generalize any discrete baseline model. After proposing the new
class, two special discrete models are investigated and discussed in detail.
Some mathematical and statistical properties including, probability mass
function, hazard rate function, quantile, crude moments, index of
dispersion, entropies, order statistics, and L-moment statistics, are
derived. It is found that the presented discrete class can be used to model
symmetric and asymmetric data under different types of kurtosis shapes. It
can be utilized to explain and analyze overdispersion data with extreme,
zero-inflated or outliers? observations. Furthermore, it can be applied to
discuss various shapes of hazard rates including monotone increasing,
monotone decreasing, unimodal, bathtub, unimodal-bathtub, among others. We
discuss the estimation of the class parameters by the maximum likelihood
approach. The performance of the estimation method is tested via Markov
chain Monte Carlo (MCMC) simulation technique. Finally, to demonstrate the
proposed methodology in a real-life scenario, three real data sets are
considered to show the applicability of the proposed generator.
Orlicz mixed projection body
Authors: Zhao Chang-Jian
Published: March 2024

In the paper, our main aim is to generalize the mixed projection body ?(K1,...,Kn?1) of (n ? 1) convex bodies K1,...,Kn?1 to the Orlicz space.
Under the framework of Orlicz-Brunn-Minkowski theory, we introduce a new
affine geometric operation call it Orlicz mixed projection body ??(K1,...,Kn) of n convex bodies K1,...,Kn. The new affine geometric quantity in
special case yields the classical mixed projection body ?(K1,...,Kn?1)
and Orlicz projection body ??K of convex body K, respectively. The related
concept of Lp-mixed projection body of n convex bodies ?p(K1,...,Kn) is
also derived. An Orlicz Alesandrov-Fenchel inequality for the Orlicz mixed
projection body is established, which in special case yields a new
Lp-projection Alesandrov-Fenchel inequality. As an application, we establish
a polar Orlicz Alesandrov-Fenchel inequality for the polar of Orlicz mixed
projection body.
Some weighted Hadamard and Ostrowski-type fractional inequalities for quasi-geometrically convex functions
Authors: Kalsoom Humaira , Amer Latif Muhammad
Published: March 2024

It is well knowledge that the purpose of inequality is to develop various
approaches to mathematical problem solving. In order to prove the
originality and existence of mathematical techniques, it is now necessary to
seek exact inequalities. In the present research, we propose some novel
weighted fractional Ostrowski-type inequalities for functions which are
differentiable and satisfy quasi-geometrically convex using a new identity.
Moreover, outcomes for functions with a bounded first derivative are proved.
Finally, some examples are given to illustrate the investigated results. The
obtained results generalize and refine previously known results.
Organizational digital development and digital competencies required for managers in different positions: The human resource management perspective
Authors: Kovacevic Ivana , Andjelkovic-Labrovic Jelena
Published: March 2024

Organizational digital develo pment requires new competencies from managers.
The aim of the research was to establish the relation between the assessed
level of the companies` digitalization and the assessment of the required
level of digital competencies for managers in different managerial positions
(operational, middle, and executive). The respondents included 97
professionals employed in a human resource department who filled an online
scale the digital development level in companies and a modified scale based
on the European digital competence framework. The results show that the
higher assessment of the organizational digital development predicts the
higher level of required digital competencies, regardless the managerial
position, followed by the main effect of the managerial position on the
required level of digital competencies, with no differences in competency
domains. They indicate the importance of the organizational setting in the
context of the expected digital competency, as well as the existing
differences in the level but not in the domain requirements for competencies
related to the managerial position. Findings should be interpreted in the
context of the limitations stemming from the sample and the fact that both
assessments were carried out by the same respondents who might not be the
experts in organizational digital development.
Youth and trade unions in Croatia: An overview and analysis of some theoretical and empirical insights
Authors: Jeknic Ranka
Published: March 2024

Based on the review and analysis of scientific and trade union literature, as
well as the comparison of various primary and secondary research data at the
level of descriptive statistics, this paper aims at answering some of the
questions that arise in relation to the attitudes of young people in Croatia
towards trade unions: the various reasons for young people?s non-membership
or reduced membership in trade unions, the increase in young people?s
distrust of trade unions, and the question of how familiar young people in
Croatia are with collective labour rights and, in general, with the work and
activities of trade unions in Croatia. The theoretical and empirical
findings, presented and analysed, as well as the conclusions of this paper,
could contribute to a better understanding of the attitudes of young people
in Croatia towards trade unions, and could have an application value in the
design of labour rights education programmes in the framework of civic
education, as well as in the implementation of various activities to attract
new members among trade unions themselves in the Republic of Croatia.
Higher Expression of Lympho-epithelial Kazal-type-Related Inhibitor-1 Fragments and Decreased Desquamation in the Lesional Skin of Nummular Eczema
Authors: Montenegro Sara Estefania , Oh Jang-Hee , Suh Joong Heon , Mun Je-Ho , Chung Jin Ho
Published: March 2024

Nummular eczema, a chronic dermatitis characterized by coin-shaped lesions, was first documented in 1857. However, its pathophysiological characteristics are still not well known. To investigate differences in the regulation of the desquamation process in the stratum corneum of lesional and nonlesional skin of patients with nummular eczema and healthy control subjects, tape-stripped stratum corneum samples from patients with nummular eczema and healthy volunteers were analysed using immunofluorescence staining and western blot analysis. In the nummular eczema lesional skin, expression of desmoglein-1, desmocollin-1, and corneodesmosin exhibited a disorganized, dense or partially diffuse non-peripheral pattern with increased intensity, compared with the peripheral patterns observed in healthy or nonlesional skin, suggesting the impaired desquamation process in nummular eczema. Furthermore, although the expression of the desquamation-related serine proteases, kallikrein-related peptidase 7 and 5, was increased in nummular eczema lesional skin, the immunofluorescence staining of lympho-epithelial Kazal-type-related inhibitor-1, an endogenous inhibitor of various kallikrein-related peptidases, and its fragments were significantly increased in the nummular eczema lesional skin, suggesting its contribution to the inhibition of corneodesmosomal degradation. Therefore, the increased detection of corneodesmosomal proteins in nummular eczema lesions may be due to the increased amount of the fragments of lympho-epithelial Kazal-type-related inhibitor-1, which could contribute to delayed desquamation.
PDL1 in Cancer: A Remarkable Mile Stone Achieved
Authors: Shankaralingappa Arundhathi
Published: March 2024

PD-1, or programmed cell death protein 1, is indeed a critical immune checkpoint receptor expressed on activated T lymphocytes, including tumor-specific CD4+ helper and CD8+ killer T cells. Originally, PD-1 was identified as a regulator of cell death, but its role in immune regulation has since been recognized as crucial in the context of cancer immunotherapy.
Obesity: A Major Factor in Diabetes
Authors: Tahreem Hafsa
Published: March 2024

Obesity is currently recognized as a significant risk factor contributing to the onset of diabetes, presenting a substantial challenge to public health worldwide. This abstract provides a concise overview of the intricate relationship between obesity and diabetes, with a specific focus on the impact of excess body weight on insulin resistance and beta-cell dysfunction. These two mechanisms serve as the primary contributors to the development of diabetes. The abstract delves into the complex interplay between adipose tissue, insulin signaling, and inflammation, elucidating the underlying mechanisms by which obesity exacerbates insulin resistance. Additionally, the role of visceral adiposity, genetic factors, and lifestyle modifications are explored within the context of obesity-related diabetes. The abstract also highlights the adverse health consequences associated with obesity-related diabetes, particularly the heightened risk of cardiovascular disease and other comorbidities. Acknowledging these detrimental effects strengthens the urgency in addressing this widespread issue. Consequently, the abstract briefly outlines the various effective management strategies available to combat obesity-related diabetes, including weight loss interventions, pharmacotherapy, and bariatric surgery. In conclusion, the abstract underscores the necessity of adopting a comprehensive and multidisciplinary approach in tackling both obesity and diabetes. Prevention measures are emphasized as a crucial component in alleviating the burden posed by these two interrelated health conditions. By implementing proactive strategies, it is possible to mitigate the escalating prevalence of obesity-related diabetes and enhance public health outcomes.
The State of Diabetes: Understanding India's Epidemic
Authors: Selvin Rosilda
Published: March 2024

Globally, the prevalence of diabetes is increasing as a result of ageing populations, urbanisation, obesity rates, and decreased physical activity. Diabetes affects young to middle-aged adults disproportionately in Asian countries, in contrast to the West where the disease primarily affects older people. This could have detrimental long-term implications on the economy and health of a country, particularly for emerging nations. According to projections from the International Diabetes Federation (IDF), there were around 50.8 million diabetics in India in 2010; by 2030, that number is expected to rise to 87.0 million. Reaching a near-normal glycaemic level is the main objective in the treatment of diabetes mellitus. In India, vascular problems and inadequate glycaemic management affect almost half of the patients. Consequently, the development of innovative treatment drugs for diabetes that do not compromise safety or cause complications to worsen is desperately needed. Despite extensive research on diabetes, a cure remains elusive for patients. As a result, this overview discusses current developments in diabetes research, treatment, and therapy.
Inventorying the Broodstocks of Belarusian Carp Breeds and Herbivorus Fish Species by the Genes of the Most Economically Valuable Traits to Maximize the Use of the Physiological Potential of a Fish Organism to Increase Fish Productivity in Ecological Conditions of Intensive Pond Fish Farming
Authors: AM Slukvin
Published: March 2024

One of the most promising marker genes for assessing and predicting animal meat productivity is the myostatin gene (MSTN). The protein encoded by this gene regulates the development of muscle tissue in various species of terrestrial and aquatic vertebrates. Mutations of the myostatin gene may lead to a twofold and in some cases even a threefold increase in muscle mass in the individuals of different species. Studies are underway to test the breeders of the Belarusian mirror carp and herbivorous fish species for the presence of mutations in the myostiatin gene (MSTN). When revising the broodstock of a new species of the Belarusian mirror carp, the effectiveness of using mutations of the MSTN gene associated with an economically valuable trait of fish productivity and mass accumulation has been established. The fish capacity of the juvenile mirror carp obtained during the reproduction of test breeders, where one parent was a GG homozygote and the other was an AG heterozygote with a mutation by the MSTN gene, was 1.3-1.7 times higher compared to the average productivity in the experimental and control groups and it showed a better productivity indicator for the control groups by 1.1-1.5 times. When testing silver carp and bighead carp selected for study (in Belarus and Uzbekistan), no mutations in the myostatin gene (MSTN) were found.
Mapping of Urban Heat Island in West Semarang Subdistrict, Semarang City of Indonesia
Authors: Suparta Wayan
Published: March 2024

One of the top ten hottest cities in Indonesia is Semarang City which is characterized by a high level of density. This research aims to classify urban heat conditions, particularly in West Semarang Sub-district, through Urban Heat Island mapping. The mapping and analysis stages include Top of Atmosphere (ToA), Brightness Temperature (BT), Normalized Difference Vegetation Index (NDVI), Proportional Vegetation Index (PVI), Error Correction (EC), and Land Surface Temperature (LST). The results of investigations based on maps produced from ArcGIS show that areas in West Semarang District can be classified into high, moderate and low temperature categories. Tambakharjo Village is the area with the highest temperature, whereas part of this area is found with low temperature, and moderate temperatures dominate almost all villages in West Semarang sub-district. The high heat that occurs in Tambakharjo is caused by fisheries production activities.
Antibacterial Activities in Upper River Benue Surface Water With Diospyros Mespiliformis Seed Extracts
Authors: AM Mohammed
Published: March 2024

In this study, the extracts of Diospyros Mespiliformis; crude seed, mucilage and seed was used to investigate the potential effect of microbial activity and percentage turbidity reduction on surface water. The Sample water were collected from Upper River Benue at Jimeta Bridge. The sample was collected in Jerry cans (50 litters) transported to wet Laboratory, Department of Fisheries, School of Agriculture, Modibbo Adama University of Technology Yola. Portion of the water fetched were transferred to microbiology laboratory of same University for antibacterial test where three bacteria wer selected for the analysis. Moreover, part of the sample were used for Turbidity Test. Data obtained were analyzed using Analysis of Variance (ANOVA). The Result shows the potency of D. mespiliformis extracts on surface water and percentage turbidity reduction. The following bacteria; Escherichia coli, Bacillus subtilis and Staphylococcus aureus were used for the evaluation with E. coli recorded it highest mean of inhibition zone of 21 and zero as it lowest for crude seed at 15mg/l, 22 highest and zero is the lowest for seed mucilage at 15mg/l and 22 was the highest and zero lowest for seed extracts at 10mg/l. B. subtilis had highest mean of inhibition zone of 15 and zero as it lowest for crude seed, 20 highest and zero is the lowest for seed mucilage and 20 was the highest and zero lowest for seed extracts. S. aureus had highest mean of inhibition zones of 24 and zero as it lowest for crude seed, 20 highest and zero it lowest for seed mucilage and 22 was the highest and zero is the lowest for seed extracts. D. mespiliformis extracts succeeded by reducing very high percentage of the turbid water. D. mespiliformis extracts should be used hence forth use as primary coagulants for treatments of raw water for its ability to inhibit bacteria growth.
Assessment of Irrigation Potential in Jewuha Watershed, Middle Awash River Basin, Ethiopia
Authors: Beza Manamno , H Hailu
Published: March 2024

Ethiopia is endowed with immense water and land resources that could be tapped and used for irrigation development. However, little has been done so far due mainly to lack of comprehensive knowledge on the potential of these resources. This study was, therefore, taken up to assess the irrigation potential in data scarce Jewuha watershed of the Awash River Basin. To achieve the objective of the study, the suitability of the land for both surface and pressurized irrigations was estimated using a parametric evaluation technique combined with the FAO land evaluation framework in the GIS environment with multi-criteria analysis of irrigation suitability factors. The irrigation water demands of major crops adopted in the area were determined using CROPWAT software. The surface water potential at the sub watershed was estimated using a combination of SWAT model and the spatial proximity regionalization technique. The performance of the SWAT model was checked by statistical parameters. The irrigation suitability analysis reveals that 51372ha of the study area are suitable and 16274ha are unsuitable for surface irrigation system. Furthermore, 52768ha of the area are suitable and 15088ha are unsuitable for a sprinkler irrigation system. For drip irrigation, 52751ha are suitable and 14855ha are unsuitable. The calibration and validation of SWAT model showed that the model has performed well to simulate the hydrology of the watershed with a coefficient of determination (R2), Nash-Sutcliffe efficiency (NSE) and Percent of bias (PBIAS) of 0.74, 0.73 and 0.80 for calibration and 0.71, 0.70 and 7.90 for validation, respectively. From a combined analysis of the available land and water resources, the gross irrigation potential of the area is estimated to be 12,997ha, of which 3098ha of land is exclusively suitable for surface irrigation and 9,899ha is suitable for pressurized irrigation systems.
Assessing Threats to the Drill monkey (Mandrillus leucophaeus) and other Primate Species in Selected Ranges of Cross River National Park, Nigeria
Authors: EE Ofuya
Published: March 2024

The population of the endangered drill monkey (Mandrillus leucophaeus) and other primate species have continued to decline in Cross River National Park (CRNP), Nigeria. The current threats responsible for the population decline was assessed in four selected ranges (Anape, Aking Orem and Nsofang) through administrative park record, interview of hunters and field observations that spanned 194days (between July, 2021 – August, 2022) covering a distance of 997km. A total of 58 interviews of hunters were conducted in seven communities (Anape, Aking, Osomba, Orem, Ntebachot, Nsofang and Mkpot). Ninetyfive (95%) reported a decline in the population of the drill monkey as (65%) stated a rare encounter. Also, 90% reported to hunt primates with 64% reporting to hunt drill monkey even though they are aware of the existence of CRNP. However, 79% expressed their willingness to stop hunting if an alternative livelihood was provided. Thirteen threat indicators were recorded in both season (wet and dry), distributed across the four ranges surveyed. Spent cartridge (dry=12.75±10.41; wet=6.25±5.91), wire snare (dry=8.25±4.73; wet=8.5±3.42) and logging (dry=3.75±3.61; wet=3.50±2.65) were the highest threat indicators and correlated with the administrative record on threat in a ten year period (2012 -2021) (hunting 34.3% and logging 35.5%). Encounter rate of threat was highest in Nsofang (dry=0.78/km; wet=0.76/km) which harbours an enclave community (Mkpot) and lowest at Anape (dry=0.05/km; wet=0.18/km) suggesting more protection of this area considering the conservation interest in the region. The Park authority is therefore implored to intensify protection efforts in these other areas with high anthropogenic activities while considering the possibility of a joint forest management with host communities.
The Impact of Artificial Intelligence on the Uptake of Mammography Screenings in Women
Authors: Beverley Dr. Charles
Published: March 2024

This comprehensive review examines the role of artificial intelligence (AI) in influencing the uptake of mammography screenings in women. The review includes an analysis of peer-reviewed articles exploring the various aspects of AI's impact on breast cancer screening rates, accuracy, efficiency, patient experiences, and cost-effectiveness. Through this analysis, the review aims to shed light on the potential of AI to enhance breast cancer screening practices and outcomes.
Nanomedicine and Nanorobot: Mini Review
Authors: Kumar Sudesh
Published: March 2024

Nanotechnology is now recognized as an emerging field for scientific study and technological advancement, along with associated concepts like nanomaterials, nanostructures, and nanoparticles. Electronics and other disciplines have already benefited greatly from the development and use of nanotechnology or the manufacture and use of devices and materials at the nanoscale. The field of nanomedicine is a developing one that combines medical science with nanotechnology to create new therapeutics and enhance current ones. When interacting with human cells, nanomedicine uses the manipulation of atoms and molecules to produce nanostructures the same size as biomolecules. This technique offers a variety of cutting-edge choices for diagnostics and intelligent therapies by supporting the body's inherent healing systems. One of the most exciting uses of nanomedicines is the development of nanobots, which is leading multidisciplinary research. Nanotechnology breakthroughs have led to an increased application of nanobots in cancer diagnosis and treatment. They allow the creation and deployment of functional molecular and nanoscale machines. The use of nanobots in cancer treatment has moved from theory to reality in recent years, with a shift from in vitro trials to in vivo applications.
A Review on Advancing Sustainability: Exploring the Potential of Cork and Granite Sludge Composite Materials in Infrastructure Development
Authors: Jalgar Sandhya
Published: March 2024

In recent years, material scientists have been focusing on the utilization of materials from natural resources due to environmental concerns. The previous researches and investigations show the importance of cork and granite sludge in the Construction activities. The study is based on the use and tests carried out on Cork and Granite Sludge to know about their properties. With the same context the aim of this research paper is to highlight the use and credibility of using the natural materials Cork and Granite sludge in combination with Cement in building construction. Cork displays a high degree of stability under varying conditions. This is paramount to its continual usage and success throughout the world today. Cork is a tough, durable substance with a remarkable capacity for retaining its initial properties. Cork’s many air cells also contribute to excellent acoustic benefit, providing efficient sound resistance above and below the floor. Cork is an effective way to muffle the sound of children playing in a room above, or reduce the echo found with “other” hard surface floors in a media room. Cement replacement with granite in small amounts leads to better dispersion of cement particles in the mix which results in better cement reactions and finally improvements in strength and other characteristics of concrete. The various properties and characteristics of Cork and Granite Sludge are highlighted in this paper which make them the most sustainable materials and contribute to Resilient Structures.
Classical and Quantum Descriptions of the Geometrodynamics of Black Holes
Authors: Danilovich Gladush Valentin
Published: March 2024

Analytical aspects of the classical and quantum geometrodynamics of charged black hole are considered. We start with a reduced action for a spherically symmetric of Maxwell-Einstein system written in characteristic variables. The feature of these configurations is that they admit two motion integrals, the total mass and charge. Momenta and constraint are introduced. Using the conservation laws and the Hamiltonian constraint, the momenta as functions of configuration variables are found. It turns out that the system of equations relating momenta and functional derivatives of an action on a configuration space (CS) is integrable. This allows us to obtain the action functional, as a solution of the Einstein-Hamilton-Jacobi equation in functional derivatives. Variations of the action functional with respect to mass and charge of the configuration lead to the motion trajectories in the CS. Further, the space-temporal action is transformed into an action in the configuration space similar to the Jacobi action of classical mechanics. This induces a metric in the CS. Thus, the metric on the CS is introduced and its geometry is studied. The field variables transformation is obtained which brings the CS metric to the "quasi-Lorentzian" form. On this basis, quantization is considered. Taking into account the structure of the CS, the momentum operators, DeWitt equations, mass and charge operators are constructed. Further, for comparison, consider the reduced CBH model defined in the T-region. In this simplified formulation, the T-model equations are integrated and lead to CBH with a continuous spectrum of mass and charge.
Constraining the Milky Way Dynamic Mass and Newtonian Gravity through the Proper Motion of Messier’s Globular Clusters
Authors: Falcon Nelson
Published: March 2024

The estimation of the proper motion of globular clusters is presented from the oldest observations of Messier's Globular clusters, comparing with NASA-NED and GAIA. The period-distance relationship, without assuming Dark matter models, allows us to limit the dynamic mass of the Milky Way and the invalidity of the Keplerian movement of Globular Clusters. The best fitting data are 14 2.3 0.3210 ± M for the dynamical mass, and β ≅ −5 3 in agreement with the generalization of the Virial Theorem in large-scale modified Newtonian gravity models.
Effects of Lime, Inorganic Fertilizer and Compost as Amendment on Soil Chemical Properties: Field Experimental Approach to Reclaim Acidic Nitisol, South Western Ethiopia
Authors: Dadi Tadie Girma
Published: March 2024

Soil acidity is a series problem in south western part of Ethiopia due to high rain fall that aggravate the concentration of toxic elements like Al3+ and Fe2+. This study was conducted to evaluate the effects of lime with different fertilizer sources on soil chemical properties at Seka chekorsa area. Seven different treatments were applied with randomized complete block design along three replications. The study pointed out the response of soil pH (5.01) which was increased by 91.8% when compared to control plot (4.60), H+(0.25 cmol/kg), Al3+(0.19 cmol/kg), Exchangeable Acidity (0.44 cmol/kg), Available Potassium (1.96 Cmol/kg) and CEC (22.76 Cmol(+)/Kg) were attained significantly different result at (p<0.05) on CompL treated plot. However, OC (2.14%) and OM (3.69%) were attained the highest result on HCHNP and TN (0.1%) and Available K (2.00Cmol/kg) was significantly different at (p<0.05) on HCHNPL treated plot. The combined application of compost with lime was better than other combination including solely applied treatments to enhance different soil chemical properties in most of soil parameters. The integration of lime with organic and inorganic nutrient sources generally increased soil pH when compared with sole applied and control plot. Finally, the Integration of full recommended compost and Lime of agriculture could be promising alternative to amend acidic nitosol.
New Approaches of Root Stocks in Fruit Production: A Review
Authors: Kumar Ashok
Published: March 2024

Rootstocks play an essential role to determining orchard performance of fruit trees. Pyrus communis and Cydonia oblonga are widely used rootstocks for European pear cultivars. The lack of rootstocks adapted to different soil conditions and different grafted cultivars is widely acknowledged in pear culture. Cydonia rootstocks (clonal) and Pyrus rootstocks (seedling or clonal) have their advantages and disadvantages. Selecting the right combination of the rootstock and cultivar is important for optimizing fruit quality parameters. Dwarfing is an important agricultural trait for intensive cultivation and effective orchard management in modern fruit orchards. Commercial citrus production relies on grafting with rootstocks that reduce tree vigour to control plant height. Citrus growers all over the world have been attracted to dwarfing trees because of their potential for higher planting density, increased productivity, easy harvest, pruning, and efficient spraying. Dwarfing rootstocks can be used to achieve high density. Citrus rootstocks with dwarfing potential have been investigated regarding physiological aspects, hormonal communication, mineral uptake capacity, and horticultural performance. This study lays the foundation for future research into the genetic and molecular mechanisms underlying citrus dwarfing. Many of the rootstocks now available to growers of apples, pears, peaches, nectarines, apricots, cherries and plums are listed and described briefly. Future rootstock needs for these and other crops are anticipated. Alternatives to rootstocks are considered, in particular the opportunities for scion cultivar improvement which may be offered by the developing techniques of molecular biology. Finally, the need for a better understanding of the physiology of the effects of rootstock on scion growth and cropping is emphasized.
Alzheimer's Disease and Frailty: A Complex Relationship
Authors: Lima de Araujo Edivaldo
Published: March 2024

The world’s population is ageing rapidly and in developing countries this is more evident. Cognitive decline and physical frailty are frequent situations in the ageing process, and so there is a progressive increase in neurodegenerative diseases, dementias, and new health conditions, such as frailty [1].
Early Identification and Intervention for Infant Speech and Language Delays: A Narrative Review
Authors: Sakhai Farhad
Published: March 2024

Language is one of the most basic communication tools for human social and behavioral activities. Language is a form of cognitive expression that reflects the thinking and psychological processes of the human brain. Because language is central to so many aspects of human life – cognition, social interaction, education and vocation – valid identification, prevention, and treatment of language disorders is a high priority for the therapeutic professions. Delay and/or difficulty in beginning to use the language is one of the most common causes of parental concern for young children brought to pediatricians and other professionals. The importance of early intervention is acknowledged by professionals and non-professionals alike. It advocates promotion of positive assets and development of the child and the family. The major purpose of early intervention is prevention of disability and developmental delays. The ultimate goal in intervention is to enhance normal development and independent functioning of the child. Intervention may focus on the child, parents, family, and community