bluuebunny/crossref_metadata_2025 huggingface dataset:
An evolutionary ecomorphological perspective on the assembly of a Neotropical bat metacommunity
Authors: Acero-Murcia Adriana Carolina , Severgnini Marcos R. , Fischer Erich , Provete Diogo B.
Published: November 2022

The evolution of bat skull has been extensively studied at a broad scale. However, we know little about how phenotypes that evolved in response to selective pressure elsewhere interact with ecological pressures to determine species co-ocurrence in human-modified landscapes. Here, we test the influence of size, diet, and foraging strategy on the skull and jaw shape of 32 co-occurring bat species in an agroecological landscape from southwestern Brazil. We used 2D geometric morphometrics for skull and jaw and phylogenetic comparative methods to integrate morphology, ecology, and phylogeny data. Our results show that closely related species were clustered together in the morphospace. Likewise, ecology and phylogeny influenced the cranial and jaw shape. Groups with greater phenotypic disparity were animalivores and insectivores. The skull of frugivores and animalivores were larger than that of insectivores and had a common and positive allometric relationship, probably related to olfactory-visual senses. Apparently, coexistence in Stenodermatinae frugivores is possible because they have optimal phenotypes for exploration food resources related to the skull and jaw size. Conversely, insectivores that clustered together in the morphospace had differences in foraging strategy or size.
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands
Authors: Gao Jing , Li Aonan , Fujii Shinsuke , Huang Fei , Nakatomi Chihiro , Nakamura Ichiro , Honda Hiroaki , Kiyoshima Tamotsu , Jimi Eijiro
Published: November 2022

Salivary glands develop through epithelial-mesenchymal interactions and are formed through repeated branching. The Crk-associated substrate protein (p130Cas) serves as an adapter that forms a complex with various proteins via integrin and growth factor signaling, with important regulatory roles in several essential cellular processes. We found that p130Cas is expressed in ductal epithelial cells of the submandibular gland (SMG). We generated epithelial tissue-specific p130Cas-deficient (p130CasΔepi–) mice and aimed to investigate the physiological role of p130Cas in the postnatal development of salivary glands. Histological analysis showed immature development of granular convoluted tubules (GCT) of the SMG in male p130CasΔepi– mice. Furthermore, epidermal growth factor (EGF)-positive secretory granules contained in GCT cells were significantly reduced in p130CasΔepi– mice with downregulated androgen receptor signaling. Deficiency of p130Cas resulted in a decrease in Rab3D-positive vesicles, disturbed intracellular localization of the cis-Golgi matrix protein GM130, and decreased expression of endoplasmic reticulum (ER) markers such as Lys-Asp-Glu-Leu (KDEL) and calnexin in GCT cells. Thus, p130Cas plays a crucial role in androgen-dependent GCT development in SMG by regulating the formation of the ER-Golgi network.
STING mediates experimental osteoarthritis and the associated pain behavior in mouse
Authors: Shin Youngnim , Cho Deborah , Kim Seul Ki , Chun Jang-Soo
Published: November 2022

Background. This study was performed to develop therapeutic targets of osteoarthritis (OA) that can be targeted to alleviate OA development (i.e., cartilage destruction) and relieve the OA-associated joint pain.
Methods: The candidate molecule, STING (stimulator of interferon genes, encoded by Sting1), was identified by microarray analysis of OA-like mouse chondrocytes. Experimental OA in mice was induced by destabilization of the medial meniscus (DMM). STING functions in OA and joint pain were evaluated by gain-of-function (intra-articular injection of a STING agonist) and loss-of-function (Sting1-/- mice) approaches.
Results: DNA damage was observed in OA-like chondrocytes. Cytosolic DNA sensors, STING and its upstream molecule, cGAS (cyclic GMP-AMP synthase), were upregulated in OA chondrocytes and cartilage of mouse and human. Genetic ablation of STING in mice (Sting1-/-) alleviated OA manifestations (cartilage destruction and subchondral bone sclerosis) and OA-associated pain behavior. In contrast, stimulation of STING signaling in joint tissues by intra-articular injection of cGAMP exacerbated OA manifestations and pain behavior. Mechanistic studies on the regulation of OA pain revealed that STING regulates the expression of peripheral sensitization molecules in the synovium and meniscus of mouse knee joints.
Conclusion: Our results indicated that the cGAS-STNG pathway in chondrocytes, which senses damaged cytosolic DNA and accordingly activates the innate immune response, regulates OA pathogenesis and joint pain. Therefore, inhibition of STING could be a therapeutic approach to inhibit OA cartilage destruction and relieve the associated pain in model mice.
Investigating the effect of PAMAM-G2 nanostructures dendrimer on the performance of polycarbonate thin film nanocomposite membranes for water treatment
Authors: Khezraqa Homayun , Etemadi Habib , Salami-Kalajahi Mehdi
Published: November 2022

For the first time, thin film nanocomposite membranes (TFN) were fabricated using polyamidoamine polymer nanostructures(PAMAM-G2) through the use of the dip-coating method that polyvinyl alcohol (PVA)/PAMAM-G2 solution was applied to polycarbonate (PC) support membranes. The Fourier transform infrared (FTIR) and thermal gravimetric analysis (TGA) confirmed the synthesis PAMAM dendritic structure. At vacuum trans-membrane pressures (TMP) of 0.4 and 0.6 bar, all fabricated membranes were utilized to remove humic acid (HA) from submerged membrane filtration. PVA/ PAMAM-G2 top active layer formed on the PC support membrane was verified by images obtained using field-emission scanning electron microscopy (FESEM) and attenuated total reflectance-Fourier transform infrared (ATR-FTIR) equipment. FESEM images show that a PVA-PAMAM.G2 top layer with a thickness of 201.85 nm was developed on the PC support layer. TFN membranes' hydrophilicity and surface roughness increased and decreased respectively as a result of the incorporation of PAMAM-G2. The TFN with 0.1 weight percent of PAMAM-G2 nanostructures demonstrated increased permeation flux at lower vacuum TMP, according to the results of HA filtration. However, TMP permeate flow significantly decreased at higher vacuum conditions. The rejection rate for TFC membranes was about 97.9% while for TFN membranes in the presence of PAMAM-G2 polymeric nanostructure it reached 98.5%.
Plasmonic Dielectric Response of Finite Temperature Electron Gas
Authors: Akbari-Moghanjoughi Massoud
Published: November 2022

In this research we report the dielectric response of a finite temperature electron gas, electrostatically interacting with both external and self-induced plasmonic fields, in the well-known random phase approximation. The generalized energy dispersion relation which incorporates the plasmonic band structure is used to calculate the Lindhard dielectric response of homogenous electron gas from which many important physical functionals, such as the structure factor, loss function, screening potential, optical reflectivity and electronic stopping power are deduced. The present dual length-scale theory of dielectric response incorporates both single electron as well as collective electrostatic oscillation of electrons which, due to the Van-Hove-like singularity at plasmon wavenumber, shows distinct features of plasmonic response to electromagnetic interactions of the electron gas with arbitrary degree of electron degeneracy. It is shown that the static impurity charge screening potential is oscillatory Lennard-Jones-type attractive potential which is quite different from both predicted by the Conventional noninteracting Lindhard theory and the Shukla-Eliasson attractive potential obtained from quantum hydrodynamic approach. It is also revealed that due to resonant electron-plasmon interactions and multi-pole structure of the electronic response function the Landau damping region is scattered. The findings of current research may have important implications for a wide range of physical phenomena relevant to a broad nonrelativistic electron density-temperature regime, from the laboratory scale semiconductors and nanoelectronic technology to the warm dense matter state.
The Contribution of the Single-knot Fascia Closure as a New Technique in Reducing Postoperative Cesarean Section Pain
Authors: Atilgan Remzi , Pala Şehmus , Halisçelik Mesut Ali , Şenocak Ahmet , Çim Bünyamin
Published: November 2022

Introduction: After cesarean section, many women complain of postoperative incision site and abdominal pain. Surgical techniques can be effective in relieving this pain to some extent. We compared the effects of single-knot fascia closure technique and classical fascia closure technique on postoperative pain in fascia closure.
Methods: A total of 80 cases were included in this prospective, randomized, single-center study. Classical fascia closure method was applied to one group and single-knot fascia closure method was applied to the other group. Pain was evaluated with Visual Analogue Scala (VAS) at 8 and 24 hours postoperatively. The cases were followed up for the development of infection, hematoma, seroma and hernia at the wound site within 3 months postoperatively.
Results: Wound infection, seroma, hematoma and hernia did not develop in the postoperative period in both groups. However, VAS values ​​at the 8th and 24th hours were significantly lower in the group in which the single knot fascia closure method was applied.
Conclusion: Single-knot fascia closure method is an effective and reliable method in reducing postoperative pain after cesarean section.
Strategies for Reducing Communication Latency in 6G Networks
Authors: Das Satya Ranjan , Mukherjee Nandini , Sinha Bhabani P
Published: November 2022

Design of computer networks usually aims at optimizing the network performance through efficient network communication protocols to maximize resource utilization and network throughput. Over the different generations of wireless cellular network staring from first (1G) to fifth generation (5G), end-to-end communication latency, bandwidth and energy required for communication have turned out to be the most significant performance parameters to be considered for the design process. Although a significant amount of research has been done in this direction over the last few decades, still lot more attention needs to be given to explore the techniques for improving the end-to-end communication latency specifically in the context of recent 5G and 6G networks. This paper initially presents the expected goals of the 6G networks and the potential smart services to be enabled by 6G. In the later sections, it provides a concise survey of strategies for managing latency-related issues in the literature. Next we focus on the types and sources of delays that affect latency, the enabling technologies for 6G implementation and the potential strategies for reducing latency. Finally, we discuss about some significant challenges and identify a few open research problems to achieve ultra-low end-to-end latency in 6G communication.
Enhanced production of falcarinol-type polyacetylenes in hairy roots of cultivated carrot (Daucus carota subsp. sativus)
Authors: Dunemann Frank , Böttcher Christoph
Published: November 2022

Polyacetylenes (PAs) are a large group of bioactive phytochemicals, which are primarily produced by higher plants of the families Apiaceae and Araliaceae. Especially aliphatic C17-polyacetylenes of the falcarinol-type such as falcarinol (FaOH) and falcarindiol (FaDOH) are known for their numerous biological functions including positive effects on human health. In this study we investigate the potential of carrot hairy root (HR) cultures for accumulation of PAs in vitro. Three individual plants of seven differently colored carrot cultivars were used for the development of HR cultures by transformation of root discs with the wild-type Rhizobium rhizogenes strain 15834. A total of 51 individual HR lines were established and quantitatively analysed by HPLC/DAD together with root, petiole and leaf tissue samples for their FaOH and FaDOH levels. Among the five tissues sampled from the donor plants, root periderm samples generally exhibited the highest PA levels with FaDOH as prevailing PA and large differences between cultivars. Compared with the periderm, FaOH levels were highly increased in HRs of all investigated carrot cultivars, whereas the FaDOH levels were only slightly enhanced. Considering the low to moderate PA concentration in root and leaf tissues of the orange cultivars there was an up to 30-fold increase of the FaOH concentration in HRs derived from orange genotypes. In this study, we demonstrate, that carrot HRs are able to produce large amounts of PAs. Hence, we suggest that HRs might be a suited tool to assess the function of candidate genes involved in the biosynthesis of major PAs.
PREDICTORS OF SEVERITY OF DENGUE IN PATIENTS ADMITTED TO ICU: A CROSS SECTIONAL STUDY
Authors: George K. Mary , Sanker Seena , Gomes Felly , Krishna Bhuvana
Published: November 2022

Background & Objectives: Dengue mostly causes a mild self-limiting disease but a small proportion may progress to develop severe dengue clinical manifestations, which require interventions in intensive care. The objective of the study was to describe the clinical profile, course, and outcome of dengue-infected patients admitted to intensive care units (ICU) and to evaluate factors associated with morbidity and mortality. Methods: This is an observational, descriptive study. Patients above the age of 18 admitted directly or transferred to ICU from another ward with serological evidence of dengue (positive NS1 antigen and/or IgM antibodies to dengue) were included in the study. The severity of the illness was assessed using APACHE and SOFA Scores. The primary outcome was mortality, while the secondary outcome was the length of stay in the ICU. Results: A total of 80 patients were studied and the mean age of the study subjects was 36.53 (Â± 15.28) years. The median duration of ICU stay was 2 days with an IQR of (1-3) days. The mean APACHE was 21.53 (Â±10.91) while the mean SOFA score was 12.05 (Â± 4.70). The area under the curve for the WHO classification of severe dengue was 79%, with a positive predictive value of 58.70. The area under the curve for lactate was 89% with a positive predictive value of 90.48. Interpretation & Conclusion: Lactate alone is a good predictor of mortality in severe dengue. APACHE and SOFA scores are good predictors of mortality.
LITHOSTRATIGRAPHIE ET SEDIMENTOLOGIE DES FORMATIONS SEDIMENTAIRES DE TIAPOUM, SUD-EST DE LA COTE D IVOIRE : IMPLICATION PALEOENVIRONNEMENTALE
Authors:   UFR of Geological and Mining Sciences, University of Man, BP 20 Man, Cote dIvoire., Elysee Guede Kore , Larissa Koffi Chiaye ,   UFR of Geological and Mining Sciences, University of Man, BP 20 Man, Cote dIvoire., Desire Sosthene Ronald Atto Yapi ,   UFR of Geological and Mining Sciences, University of Man, BP 20 Man, Cote dIvoire., Rosine Adina Befa-Kandet Messou NGa-Yah ,   UFR of Geological and Mining Sciences, University of Man, BP 20 Man, Cote dIvoire., Al-Abidine Diarra Idriss-Zayn ,   UFR of Geological and Mining Sciences, University of Man, BP 20 Man, Cote dIvoire., Adjoua Maryline-Audrey Edjeme Kassi ,   UFR of Geological and Mining Sciences, University of Man, BP 20 Man, Cote dIvoire., Jean-Paul Yao Ngoran ,   UFR-STRM, University Felix Houphouet Boigny, 22 BP. 582 Abidjan 22, Cote dIvoire.
Published: November 2022

Tiapoumdepartment is located in the southeast of the onshore basin of Cote dIvoire. The sedimentological, granulometric and morphoscopic analyzes carried out on 24 samples from two wells made it possible to determine the lithological, granulometric and paleoenvironmental evolution of the sediments of this area. The lithological characterization of the sediments revealed four lithological facies in the department of Tiapoum. We therefore have in the direction of sedimentation, a thick layer of clay-sandy, sands intercalated with ferruginous sandstone absent at Aby crossroads and the land of the bar which thins from upstream to downstream. As for the particle size analysis, it reveals that the sands of the department of Tiapoum were deposited by free accumulation. These are well to very well graded sands with a predominance of medium grains with an asymmetry towards the fine grains. They were deposited in a fluvial-type environment transported mainly by suspension and rolling and sometimes by saltation. Morphoscopy of the quartz grains revealed an abundance of sub-angular to sub-rounded grains with a shiny blunt appearance showing fractures or cracks due to shocks between the grains during transport. The sands of the department of Tiapoum therefore come mainly from distal environments and are transported by water. The environment that prevailed during the deposit of the Tiapoum department sediments is of the oxidized continental type and reworked in places.
COMMUNITY KNOWLEDGE, AWARENESS AND ATTITUDES TOWARDS ANTIMICROBIAL RESISTANCE IN QASSIM REGION, SAUDI ARABIA
Authors: Saud Alharbi Rayan , Saleh Alharbi Fahad , Moleh Alharbi Muneer , Abduallah Alfawaz Fayez , Sanat Alharbi Omar
Published: November 2022

Introduction: Antibiotic usage for both treating infections and preventing them is escalating the problem of antimicrobial resistance (AMR). Antimicrobial drug resistance is becoming a serious issue on a global scale. Methods: A questionnaire will be used as a study tool in a cross-sectional study to collect data from the study population. The studys randomly chosen sample of 385 residents of Saudi Arabias Qassim area will provide the data. Results: Following the findings, men made up 66.2% of the research sample, while women made up 33.8%. 59.7% of the participants had a high level of education. When we analyzed the data from the questionnaire, we discovered that the participants didnt know key crucial facts about antibiotics, which is a sign that they dont know enough about this risky topic. Conclusion: It is urgently necessary to develop educational programs for the proper use of antibiotics and the avoidance of antibiotic resistance since antimicrobial resistance is a severe worldwide issue that can result in mortality.
Determinants of sustainable consumption: Moderating role of pandemic fear
Authors: Susanti Evi , Hana Marisa Layla , Endri Endri
Published: November 2022

The Covid-19 pandemic has caused consumers to fear and feel anxious about doing activities outside their homes, such as shopping. Thus, they switched to e-commerce for sustainable consumption. This study focuses on sustainable consumption represented with the variables of perceived effectiveness of e-commerce platform (PEEP), economic benefits, interactivity, and pandemic fear. This study uses the Uses and Gratification Theory (UGT) to determine consumer motivation and purchase intentions. It explores the relationship between PEEP, economic benefits, interactivity, and sustainable consumption, with pandemic fear as a moderating variable. The analysis was conducted from February to July 2021, with e-commerce being the object of study. The study uses purposive sampling based on the criteria of respondents who have made a transaction at least once in one of the marketplaces in Jakarta, Indonesia. An online survey was employed to test 95 respondents consisting of Millennials and Generation Z who are active e-commerce users in Indonesia. The moderated regression analysis (MRA) or interaction test was applied to analyze the data. The results of the study found that pandemic fear can moderate PEEP’s relationship with economic benefits and interactivity that can increase sustainable consumption. The research findings also prove that relying on interactivity in the buying process encourages them to use e-commerce. E-commerce can help consumers who are limited in making transactions due to fear of spreading the Covid-19 virus to fulfill sustainable consumption.
Penerapan Tata Kelola Teknologi Informasi Menggunakan COBIT Framework 4.1 pada Pondok Pesantren Al Islam
Authors: Wahyu Saputra Muhammad Andryan
Published: November 2022

Saat ini, diyakini bahwa teknologi informasi (TI) berperan penting dalam meningkatkan keunggulan kompetitif. Fakta telah membuktikan bahwa teknologi informasi menciptakan nilai bagi organisasi. Organisasi semakin bergantung pada teknologi informasi agar tetap kompetitif, termasuk di Pondok Pesantren Al Islam, Kidul Pasar, Kota Malang. Dalam penelitian ini disajikan rancangan model tata kelola TI Pondok Pesantren Al Islam dengan menggunakan framework Control Objective for Information Technologies (COBIT) versi 4.1 di domain Deliver and Support (DS) dan Monitor and Evaluate (ME). Desain model disesuaikan dengan karakteristik bisnis, strategi dan tujuan Pondok Pesantren Al Islam. Penelitian ini diharapkan dapat menjadi acuan dalam pengelolaan TI di Pondok Pesantren Al Islam dan pondok pesantren lainnya. Metode penelitian dimulai dengan identifikasi visi, misi dan tujuan organisasi pondok pesantren. Langkah selanjutnya adalah identifikasi kesadaran manajemen terhadap fungsi-fungsi aset TI dalam mendukung pencapaian visi dan misi pondok pesantren. Dari data tersebut dapat ditentukan target maturitas yang sesuai untuk Pondok Pesantren Al Islam. Setelah itu, dilanjutkan dengan menilai tingkat kematangan saat ini melalui kuisioner dan wawancara kepada responden terkait dengan manajemen TI. Tindak lanjut yang dilakukan adalah dengan membuat rekomendasi pada 16 kontrol tujuan pada domain DS dan 4 kontrol tujuan pada domain ME.
Método Dialético, História e Transcendência, no Sistema Filosófico de Henrique de Lima Vaz
Authors: Mac-Dowell João Augusto Anchieta
Published: November 2022

O artigo apresenta uma visão de conjunto do pensamento de Lima Vaz, a partir de seu método original, caracterizado por seu cunho rememorativo, dialético e sistemático. Ele é aplicado particularmente na Antropologia Filosófica e na Ética, sintetizando a categoria de história com a de transcendência, superando assim a crise do pensamento moderno à luz da práxis ética.
Teologia Política e Constituição da Ordem: Carl Schmitt e a Filosofia de Estado da Contrarrevolução
Authors: Cardoso Moreira Martins Argemiro , Lopes Ramiro Caio Henrique
Published: November 2022

O objetivo deste trabalho é desenvolver uma reflexão a respeito da leitura feita por Carl Schmitt dos intelectuais católicos como filósofos de Estado da contrarrevolução. Pontualmente, o trabalho concentra-se na relação estabelecida por Carl Schmitt entre Teologia Política e Constituição, a partir da análise das reflexões De Maistre e De Bonald, em especial no que diz respeito a leitura teológico-política de categorias centrais da teoria da constituição, como, por exemplo, a questão do poder constituinte e da constituição da ordem, uma reflexão crítica de tais categorias não para restaurar a monarquia, mas, sim, apontando para a defesa da ditadura. Assim, partindo de um método hermenêutico, foram analisados os textos de bibliografia primária e, doravante, obras outras de interlocutores, bem como outros autores que se dedicaram ao problema em análise.
SPEECH-LIKE INTERFERENCE RESISTANT TO NOISE REDUCTION METHODS AS A RESULT OF SCRAMBLING OF THE PROTECTED SPEECH
Authors:   NRNU MEPHI, Dvoryankin Sergei , Dvoryankin Nikita ,   NRNU MEPHI, Ustinov Roman ,   Financial University under the Government of the Russian Federation
Published: November 2022

The aim of this article is to study the possibility of creating a speech-like interference (SLI) based on scrambling of the protected speech signal that is resistant to noise cleaning, restoration and reconstruction of distorted speech through processing of its spectrogram images, including the use of the speaker’s voice database. Methods: applied systems analysis, digital spectral-time analysis, digital processing of signals and images, image analysis of sonograms Results: it is proposed to use as the main indicator of the security of speech information the concept of potential speech intelligibility, methods for assessing potential intelligibility are determined. An algorithm of compensationtype digital noise cleaning using image analysis-synthesis technology has been developed. The requirements for the created SLI are formed, consisting in changing the spetral-temporal envelope of speech, removing («weakening») traces of the harmonic structure of speech, equalizing the capacities of the protected speech signal and the SLI masking it. The approaches to the formation of an SLI resistant to the procedures of digital noise cleaning and reconstruction of distorted sonograms are described, proposals are presented on the methodology for evaluating the effectiveness of interference through the indicator of potential intelligibility. The results obtained will allow to better understand the work of attacking tools, develop methods and means of effectively countering possible threats, and expand the capabilities of existing speech information protection systems. The scientific novelty consists in the development of criteria for evaluating the effectiveness of speech-like interference, taking into account the capabilities of the intruder to restore the intelligibility of distorted speech messages, proposed methods for the formation of scrambler-type SLI that meet such criteria, substantiated proposals to improve existing methods for assessing and monitoring the security of speech information from its leakage through technical channels.
DETECTING INFORMATION SECURITY INCIDENTS BASED ON NEURAL NETwORK TECHNOLOGY
Authors:   Mozhaiskiy Military Space Academy, Bukin Alexander , Samonov Alexander ,   Mozhaiskiy Military Space Academy, Tihonov Edward ,   Mozhaiskiy Military Space Academy
Published: November 2022

Objective: develop model, algorithmic and software for detecting in real time attempts to disrupt the correct functioning of critical information infrastructure systems with neural network technologies. Methods analysis of modern machine learning methods and neural network technologies, synthesis and modeling of correct behavior of programs, algorithmization of learning processes and application of neural networks, experimental studies of developed algorithms and programs on the stand. Study results: The characteristics of machine learning methods and neural network technologies used to detect software and technical impacts and information security incidents are given. The method for solving this problem based on neural networks with LSTM and FFN architectures has been developed. The description of the algorithm and fragments of the software implementation of the method in the programming languages Python3 and Go using Tensorflow and Keras libraries is given. An important advantage of the proposed approach is the possibility of adapting the neural network in the event of a change in the mode and conditions of operation of the system. The results obtained during the experiments indicate the possibility and expediency of using this approach to detect software and technical impacts on critical information infrastructure systems on a time scale close to real with a high level of reliability. Scientific novelty: consists in the application of deep learning technology based on a long-term short-term neural network LSTM, which has the ability to adapt to changing modes and conditions, to solve the problem of detecting signs of a violation of the correct functioning of nodes of information and telecommunications systems in real time.
USING THE RANDOM FOREST MACHINE LEARNING ALGORITHM FOR THE ExTRACTION OF COMPLEx COMPUTER INCIDENTS
Authors:   Far Eastern Federal University, Pavlychev Aleksey , Starodubov Maksim ,   Far Eastern Federal University, Galimov Alexander ,   Far Eastern Federal University
Published: November 2022

The aim of the work is to develop a way to identify complex computer incidents carried out by attackers by exploiting vulnerabilities of information systems. The research method is the analysis of entries in the system logs of the Microsoft Windows operating system using the Random Forest machine learning algorithm. The result obtained: despite the wide variety of different types of malicious software used by attackers in conducting computer attacks, they all leave traces of their functioning to the network infrastructure that has been exposed to unauthorized effects. One of the ways to identify computer incidents is to examine the log files of various information systems, including the system logs of the operating system for the identification of hidden patterns and various anomalies. The functioning of any computer program can be represented as a unique set of records in the system logs of the operating system, which can be considered as features of an object. The paper analyzes the Security log of the operating system after exploiting various vulnerabilities that are popular in the hacker environment. On the data set formed in this way using a machine learning algorithm, a model is built that allows you to further identify objects that have been exposed to unauthorized effect. The scientific novelty consists in creating a way to identify complex computer incidents based on the results of studying the logs of the operating system using a machine learning algorithm.
Fuentes de costos de transacción de exportaciones peruanas: Ventanilla Única de Comercio Exterior (VUCE)
Authors: Morales Chumpitaz Nicolas J. , Pajuelo Tucto Ibeth D. , Huerta Camones Luis E.
Published: November 2022

Los costos de transacción que enfrentan los exportadores peruanos son mucho más altos que los que enfrentan los exportadores de otros países latinoamericanos. La reducción o eliminación de esos costos exigiría el conocimiento de sus fuentes. Sin embargo, hasta donde se sabe para el caso peruano, aún no han sido identificados. Por lo que, fundamentado en la teoría económica de los costos de transacción (TCT), este estudio se planteó dos objetivos, el primero fue identificar las principales fuentes de costos de transacción que enfrentan los exportadores peruanos que usan la Ventanilla Única de Comercio Exterior (VUCE); y el segundo, contribuir con la literatura relacionada con el estudio de los costos de transacción en el comercio exterior. El método utilizado consistió en la revisión de literatura, entrevistas semiestructuradas a expertos académicos economistas y el ábaco de Regnier para recopilar y analizar las opiniones de expertos profesionales en el comercio exterior. Los resultados sugieren que las principales fuentes de costos de transacción que enfrentan los exportadores son: la recolección de documentos de respaldo, la adición de documentos de respaldo, los retrasos en la frontera y la pérdida de oportunidades de negocio. Este estudio ofrece una base para profundizar la investigación, a través de métodos cuantitativos o del diseño de soluciones prácticas que permitan eliminar o reducir los costos de transacción que enfrentan los exportadores que usan la VUCE, para así contribuir con la facilitación y competitividad del comercio exterior.
Sustainable Synthesis of Benzylidenemalononitrile Compounds Under Microwave-
Irradiation
Authors: Jimenez David E.Q. , Zanin Lucas L. , Ferreira Irlon M. , Deflon Victor M. , Diniz Luan F. , Ellena Javier , Haiduke Roberto L.A. , Porto André L. M.
Published: November 2022

Abstracts:

A green methodology was developed to obtain a large scope of Knoevenagel adducts with high yields (77-95%). The compounds were synthetized in 30 min, using aromatic aldehyde derivatives, malononitrile, water as a solvent, microwave irradiation as a heating source and in free-catalyst conditions. In a particular case, in the synthesis of the adduct derived from the α-methyl-trans-cinnamaldehyde, a [2+2] photochemical cycloaddition product was observed, a tetrasubstituted cyclobutane dimeric compound 3w’. Its complex structure was confirmed by X-ray diffraction (first time), nuclear magnetic resonance analysis and electronic structure calculations. Theoretical results suggest that the thermal decomposition of 3w’ back to 3w can occur by means of a biradical intermediate.
The Flavonoid Components of Scutellaria baicalensis: Biopharmaceutical
Properties and their Improvement using Nanoformulation Techniques
Authors: Pi Jiaxin , Wang Jilin , Feng Xiaojiao , Li Ziwei , Liu Yiting , Yang Wenzhuo , Zhang Tingen , Guo Pan , Liu Zhidong , Qi Dongli
Published: November 2022

Scutellaria baicalensis georgi, known as “Huangqin” in its dried root form, is a herb widely used in traditional Chinese medicine for “clearing away heat, removing dampness, purging fire and detoxification”. Baicalin, baicalein, wogonin, and wogonoside are the main flavonoid com-pounds found in Scutellaria baicalensis. Scutellaria baicalensis flavonoid components have the po-tential to prevent and treat a host of diseases. The components of S. baicalensis have limited clinical application due to their low water solubility, poor permeability, and microbial transformation in vi-vo. Nanopharmaceutical techniques can improve their biopharmaceutical properties, enhance their absorption in vivo, and improve their bioavailability. However, due to the limited number of clinical trials, doubts remain about their toxicity and improvements in human absorption as a result of nanoformulations. This review summarizes the latest and most comprehensive information regard-ing the absorption, distribution, metabolism, and excretion of the Scutellaria baicalensis compo-nents in vivo. We examined the main advantages of nanodrug delivery systems and collected de-tailed information on the nanosystem delivery of the Scutellaria baicalensis components, including nanosuspensions and various lipid-based nanosystems. Lipid-based systems including liposomes, solid lipid nanoparticles, nanoemulsions, and self-micro emulsifying drug delivery systems are in-troduced in detail. In addition, we make recommendations for related and future research directions. Future research should further examine the absorption mechanisms and metabolic pathways of nanoformulations of the components of Scutellaria baicalensis in vivo, and accurately track the in vivo behavior of these drug delivery systems to discover the specific reasons for the enhanced bioa-vailability of nanoformulations of the scutellaria baicalensis components. The development of tar-geted oral administration of intact nanoparticles of Scutellaria baicalensis components is an excit-ing prospect.
Alcohol Consumption, Physical Activity, and CAD Risk Factors in Firefighters
Authors: Ras Jaron , Leach Lloyd
Published: November 2022

Introduction:

Firefighting is a physically and psychologically stressful occupation, where firefighters often resort to alcohol use as a coping strategy. Firefighters are particularly vulnerable to alcohol misuse and alcohol disorders, negatively affecting their health, well-being and, possibly, work performance. Therefore, this study investigated the prevalence of alcohol consumption and its relationship with the participants’ sociodemographic characteristics, weekly physical activity, and coronary artery disease (CAD) risk factors.

Methods:

This study used a quantitative, cross-sectional and descriptive design. A total of 124 full-time firefighters, males and females, were conveniently recruited from the City of Cape Town Fire and Rescue Service, South Africa, between September to November, 2020. Firefighters were then separated according to sex, age, ethnicity, and CAD risk factors. Mann-Whitney U and Kruskal-Wallis H were used to determine the statistical differences between groups, Kendall’s Tau was used to assess the correlation between ordinal and continuous variables, and Chi-square to assess the association between categorical variables. A p-value of less than 0.05 was used to indicate statistical significance.

Results:

In the present study, 72.6% (n = 90) of firefighters reported consuming alcohol, of which 75.5% (n = 74) were male and 61.5% (n = 16) were female. Of this total, 40.0% (n = 44) reported that they consumed a variety of alcoholic beverages, 32.2% (n = 36) consumed beers mainly, 14.4% (n = 16) consumed spirits mainly, and 13.3% (n = 15) consumed wines mainly. In addition, 21.1% (n = 19) were categorised as moderate drinkers and 10% (n = 9) as heavy drinkers. The overall volume of alcohol consumption was significantly different between sexes and ethnicities (p <0.05). In addition, the volume of alcohol consumption was significantly associated with sex, ethnicity, total low-intensity physical activity minutes, diastolic blood pressure, and hypertension (p = 0.005). Sex (p = 0.021) and ethnicity (p = 0.042) were significantly associated with alcohol type. The volume of alcohol consumption was a significant predictor of total low-intensity physical activity, as well as systolic (p = 0.048) and diastolic blood pressures (p = 0.036).

Conclusion:

The majority of firefighters consumed alcohol, preferred a variety of alcoholic beverages and were classified as light drinkers. Younger male firefighters consumed more alcohol than females and were more likely to be categorized as heavy drinkers. Alcohol consumption was significantly associated with sex, ethnicity, physical activity, and hypertension. Educational programs to mitigate alcohol consumption should be implemented as a preventative measure in the fire service, especially among young male firefighters.
Mental Health in Women with Vaginismus
Authors: Vakilian Katayon , Jahangiri Mohamad Mehdi , Ahangaran Setareh
Published: November 2022

Introduction:

Vaginismus disorder is one of the most common sexual disorders in women, which is characterized by involuntary muscle spasms of the outer third of the vagina and interferes with vaginal intercourse.

Objective:

The present study aimed to assess self-esteem, sexual self-concept, and irrational beliefs in vaginismus women with other women who do not have sexual problems.

Methods:

This study was a cross-sectional analytical study conducted on 60 married women aged 18 to 35 years old (vaginismus=30, control=30) by convenient sampling in 2020. The samples were selected from a sexual disorders’ clinic. The written informed consent forms were obtained. It took 30 to 40 minutes to complete the questionnaires The Multidimensional Sex Questionnaire (MSQ), The Sexual Self-esteem Inventory for Women (SSEI-W) and Jones' Irrational Beliefs Test (IBT-40). The data were analyzed using statistical methods at the levels of descriptive and inferential statistics of chi-square and t-test with SPSS 23.

Results:

According to the calculated mean for each group, it can be said that the women with vaginismus vs. control had lower score in sexual self-concept (113.33 ± 21.66 vs. 125.26± 24.32). Further, the mean of Self-esteem and irrational belief in the vaginismus and control groups were 261.40±49 vs 223.36± 46.53 and 122.26±22.49 vs 118.333 that of the control group, indicating a significant statistical difference (p=0.003).

Conclusion:

The present study showed that women with vaginismus have lower sexual self-concept and self-esteem, but their non-sexual irrational beliefs have no difference with those of non-affected women though their non-sexual beliefs are different. Therefore, it seems that medical and educational programs must focus on changing these variables.
Cracking Study Of Onyx Waste Precast Concrete Panel Which The Surface Is Finished With 4mm Thickness Grinding
Authors:   Universitas Brawijaya, Nugroho Danang Hadi , Setyowati Edhi Wahyuni ,   Universitas Brawijaya, Wisnumurti Wisnumurti ,   Universitas Brawijaya
Published: November 2022

This research is a continuation of a series of research on Tulungagung onyx waste. The large volume of onyx waste in the area around the Tulungagung onyx processing plant is used as a substitute for gravel aggregate in the concrete mixture which is processed into exposed concrete which has high aesthetic value. In this study, a finishing treatment process (panel thickness thinning) was carried out which aims to produce coarse aggregates from the walls of the onyx concrete waste panels as exposed concrete which has high aesthetic value. The researcher wanted to know the cracking behavior of the onyx concrete waste panel walls before and after the finishing process. The test object used is the test object of previous researchers, namely the wall of the onyx waste concrete panel size 80 cm x 40 cm x 6 cm with practical steel reinforcement Ã˜6 - 100 mm attached, so that in this study the researcher only carried out the finishing treatment of panel thickness thinning, in-plane three-point loading test and took data on the cracks that occurred. The result of the finishing process by grinding of 2 mm shows that the percentage of aggregate is seen on average 1.8% of the total surface area, while for the finishing of 4 mm it shows that the percentage of aggregate is seen on average 35%. No initial cracks were found on the surface of the specimen after grinding 2 mm or 4 mm. The cracks experienced after loading were flexural cracks, where all the samples had only one crack in the direction almost perpendicular to the panel axis. The bending stress that occurs in the panels during the initial cracking of the non-grinding panels, 2 mm grinding panels, 4 mm grinding panels is 4.75 MPa, 4.62 MPa, 4.60 MPa respectively.
Pengaruh Penambahan Serbuk Seng (Zno Powder) Terhadap Berat, Kuat Tekan Dan Kuat Tarik Belah Beton
Authors:   Universitas Negeri Padang, Ibrahim Maulana , Juliafad Eka ,   Universitas Negeri Padang
Published: November 2022

Indonesia is a developing country that has quite advanced industrial prospects, one of which is the zinc industry. Increased zinc production, will also increase zinc waste. Based on the nature of ZnO which readily reacts with other compounds, this compound can be used as a mixture in making concrete so that it can produce quite good structural strength. This study aims to determine how the effect of using zinc powder on weight, compressive strength and split tensile strength of concrete. The variations in the addition of zinc powder consisted of 0.25%, 0.5%, 0.75% and 1% by weight of the cement used. The test object used is a cylinder with a size of 15 cm x 30 cm. Tests for weight, compressive strength and split tensile strength were carried out when the concrete was 28 days old. The results obtained are for the weight of concrete with variations in the addition of zinc powder as much as 0%, 0.25%, 0.75% and 1% respectively of 2294 Kg / m3, 2305 Kg / m3, 2311 Kg / m3, 2305 Kg / m3, 2323 Kg / m3. Meanwhile, the compressive strength is 30.49 MPa, 30.356 MPa, 32.92 MPa, 32.69 MPa and 31.573 MPa. And for the tensile strength of concrete with the same variations, namely 11.306 MPa, 10.597 MPa, 11.976 MPa, 13.07 MPa and 13.426 MPa.
Comparative Study of Disaster Regulations in Analyzing Vulnerability Level of Elementary School Building Structures in Yogyakarta
Authors:   Politeknik Negeri Jakarta, Tiyani Lilis , Prayuda Hakas ,   Universitas Muhammadiyah Yogyakarta, Soebandono Bagus ,   Universitas Muhammadiyah Yogyakarta
Published: November 2022

This research was conducted to compare several regulations that evaluate the level of vulnerability of school buildings in Yogyakarta. The regulations used in this study are a guide to assessing and repairing damage to public housing buildings due to the earthquake according to the Department of Public Works in 2000, technical guidelines for safe school rehabilitation according to the National Disaster Management Agency in 2011, a broken one or two-story simple building block safety check guide due to the earthquake according to the 2009 World Seismic Safety Initiative and using rapid visual screening of building for potential seismic hazards according to the Federal Emergency Management Agency No. 154 of 2002. The 25 schools selected in this study were located in areas prone to earthquakes, volcanoes erupted and prone to landslides. Through this research, the results of the appropriate regulations were obtained to evaluate the rapid level of vulnerability of buildings to disasters and evaluation of certain disaster cases was needed because the regulations did not accommodate all types of disasters.
Perubahan Lahan Kritis Menjadi Lahan Hijau Sebagai Sumber Energi (Studi Kasus Das Arau Kota Padang)
Authors:   Universitas Bung Hatta, Utama Lusi , Mizwar Zuherna ,   Universitas Bung Hatta, Prayitno Eko ,   Universitas Bung Hatta
Published: November 2022

This study examines a flood control model by analyzing the area of critical land which is the land that causes flooding to become green land. Indonesia is a country that has 2 seasons, namely the dry season and the rainy season. Padang City, from 2008 - 2020, there were frequent floods. From research on the Arau watershed, there are 8 Arau sub-watersheds experiencing flooding. To reduce flooding, critical land use is converted into green land. Rainfall calculations use rainfall data from 5 stations. Rainfall plans using the Thiessen theory. Discharge plan using a rational formula. From the water discharge will be determined the amount of energy. The energy produced by the discharge of critical land use is 168,960 kwh.
Analisis Kekuatan Struktur Balok Pasca Kebakaran Pada Gedung Dengan Penambahan Pelat Baja Sebagai Perkuatan
Authors:   Institut Teknologi Adhitama Surabaya, Istiono Heri , Syafruddin Mochamad Anang ,   Institut Teknologi Adhitama Surabaya
Published: November 2022

Fire occurring in the building can cause fatal effects to the strength of building. Therefore, this research aimed at investigating the structural strength and capacity pre-fire, the remaining strength and capacity post-fire, and the structural strength and capacity after adding steel plate reinforcement. The field data involved the building of Tamansari Emerald Surabaya Apartment. The nominal moment of beam was controlled pre-fire and post-fire. The results of research demonstrated that the beam encountering fire would have moment capacity reduction at 300Â°C, 600Â°C, and 800Â°C by consecutively 0,0677%, 2,7569%, and 33,98% of the moment capacity in the normal condition. Furthermore, the reinforcement applied steel plate having the dimension 150Ã—5 mm. Thus, the increasing moment capacity after adding reinforcement gained around 60380 Kn.m.
Optimasi Desain Penampang Struktur Rangka Batang Baja Berbasis Reliabilitas Menggunakan Symbiotic Organisms Search dan Artificial Neural Network
Authors:   Universitas Kristen Petra, Husada Willy , Prayogo Doddy ,   Universitas Kristen Petra, Thamrin Christoffel Felio ,   Universitas Kristen Petra, Herdjijono Ronald ,   Universitas Kristen Petra
Published: November 2022

Safety and economic factors are the two main consideration in designing a structure. The structural engineer always try to find the optimal structure design with minimum cost that satisfy the safety requirement. This safety requirement can be expressed as structural reliability that associated to a certain failure probability threshold. An integrated Reliability-based Design Optimization (RBDO) framework usually employed to minimize the cost objective function subjected to the failure probability limit. Failure probability mostly computed by using a time-consuming Monte Carlo Simulation (MCS) method. This study develops two hybrid RBDO framework, SOS-ANN and PSO-ANN, which combine the metaheuristic method, Symbiotic Organisms Search (SOS) and Particle Swarm Optimization (PSO) with a machine learning method, Artificial Neural Network (ANN). The SOS and PSO method are used to solve the discrete optimization problem. The ANN method is adopted to replace the MCS method in predicting the reliability of every solution using binary classification. A practical RBDO case of steel truss structure is used to demonstrate the performance of both SOS-ANN and PSO-ANN method in finding the optimal structural design. The results show that the SOS-ANN method outperforms the PSO-ANN method in terms of solution quality, computational efficiency and consistency.