Demographic and Clinical Characteristics of Non Alcoholic Fatty Liver (NAFL) Patients: An Exploratory Study in a Tertiary Care Hospital
Authors: Rahman Mohammad , Abedin Mohammad , Akanda Abdur , Rahman Mohammad , Sikder Mohammad , Ahamed Marzuk , Sumon Sohel 
Published: May 2024

&lt;i&gt;Introduction:&lt;/i&gt; Non-alcoholic fatty liver disease (NLFD) is characterized by the accumulation of fat in the liver that exceeds 5% of hepatocytes, along with the development of progressive steatosis and related conditions such as hepatitis, cirrhosis, or hepatocellular carcinoma (HCC). Patients with non-alcoholic fatty liver disease (NAFLD) can display a diverse range of histological presentations, including simple accumulation of fat in the liver (steatosis), nonalcoholic fatty liver (NAFL), or nonalcoholic steatohepatitis (NASH). Non-alcoholic fatty liver disease (NAFLD) has a prevalence of 25%, impacting around 1 billion people globally. Objective: This study aimed to ascertain the demographic and clinical characteristics of non-alcoholic fatty liver disease (NAFLD). &lt;i&gt;Methodology:&lt;/i&gt; This was a cross-sectional prospective study carried out in the Department of Radiology and imaging in IbnSina Hospital, Dhaka, Bangladesh during January, 2023 to June, 2023. A total of 189 confirmed non-alcoholic fatty liver cases by CT scan, aged above 18 years were enrolled in this study. The collected data were analyzed using Statistical Package for Social Sciences (SPSS) software, version 23.0. The ethical clearance of this study was obtained from the Ethics Committee of School of Public Health & Life Science, University of South Asia, and Dhaka, Bangladesh. &lt;i&gt;Results:&lt;/i&gt; A total of 189 confirmed non-alcoholic fatty liver cases were enrolled in this study. According to age distribution, the maximum 113 (54.49%) patients were above 52 years and minimum 3 (1.58%) were between (18-22) years, and followed by 38 (20.10%) (43-52) years, 25 (13.22%), (33-42) years and 10 (5.29%) (22-32) years. The maximum 105 (55%) were male and 84 (45%) were female. The majority 132 (70%) were from urban area and 57 (30%) were from rural area. The majority 82 (43.38%) were involved in indoor job and followed by 50 (26.45%) outdoor job, 28 (14.81%) business, 20 (10.58%) not applicable and 9(4.76%) others. The BMI of the male patients was observed 132 (33.6 ± 9.5) kg/m&lt;sup&gt;2&lt;/sup&gt; and the BMI of the female was 57 (35.5 ± 8.7) kg/m&lt;sup&gt;2&lt;/sup&gt; (p=0.157). The maximum of the patients 70 (89.94% had Diabetes mellitus (DM) and followed by 66 (87.83%) Hypertension (HTN), 9 (4.76%) Cirrhosis, 8 (4.23%) Hyperlipidemia and 45 (23.80%) had Thyroid. The patients were suffering from abdominal pain, Nausea-34 (17.98%) Abdominal pain, Vomiting- 27 (14.28%), Follow Up-36 (19.04%), U. Abdominal pain-56 (29.62%) U. Abdominal pain, Jaundice-31 (16.40%) and U. Abdominal pain, Nausea-5 (2.64%). &lt;i&gt;Conclusion:&lt;/i&gt; This study investigated, the majority of the NLFD patients (54.49%) were &gt;52 years. The maximum patients were male. The majority of the patients (70%) were from urban area. The maximum patients were involved in indoor jobs. 89.94% patients had diabetes (DM). The majority of the patients suffered from U, Abdominal pain, 56 (29.62%). The difference of BMI between male and female was not observed statistically significant but both male and female patients suffered from obesity.