bluuebunny/crossref_metadata_2025 huggingface dataset:
Abruptly attenuated carbon sequestration with Weddell Sea dense waters towards the end of the 21st century
Authors: Nissen Cara , Timmermann Ralph , Hoppema Mario , Hauck Judith
Published: December 2021

Antarctic Bottom Water formation, such as in the Weddell Sea, is an efficient vector for carbon sequestration on time scales of centuries. Possible changes in carbon sequestration under changing environmental conditions are unquantified to date, mainly due to difficulties in simulating the relevant processes on high-latitude continental shelves. Using a model setup including both ice-shelf cavities and oceanic carbon cycling, we demonstrate that by 2100, deep-ocean carbon accumulation in the southern Weddell Sea is abruptly attenuated to only 40% of the rate in the 1990s in a high-emission scenario, while still being 4-fold higher in the 2080s. Assessing deep-ocean carbon budgets and water mass transformations, we attribute this decline to an increased presence of Warm Deep Water on the southern Weddell Sea continental shelf, a 16% reduction in sea-ice formation, and a 79% increase in ice-shelf basal melt. Altogether, these changes lower the density and volume of newly formed bottom waters and reduce the associated carbon transport to the abyss.
METTL3 Depletion Contributes to HR+/HER2- Breast Cancer Progression and Drug Resistance via m6A Modification of Constituents of the CDKN1A/EMT and BAX/caspase-9/-3/-8 Signalling Pathways
Authors: Ouyang Dengjie , Hong Tao , Fu Mengdie , Li Yitong , Zeng Liyun , Chen Qitong , He Hongye , Wen Ying , Cheng Yan , Zhou Meirong , Zou Qiongyan , Yi Wen-jun
Published: December 2021

Background: Chemotherapy is an important strategy for the treatment of hormone receptor positive / human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer (BC), but this subtype has a low response to chemotherapy. Growing evidence indicates that N6-methyladenosine (m6A) is the most common RNA modification in eukaryotic cells and that methyltransferase-like 3 (METTL3) participates in tumour progression in several cancer types. Therefore, exploring the function of METTL3 in HR+HER2- BC initiation and development is still significant.Methods: mRNA and protein expression levels were analysed by quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting, respectively. Cell proliferation was detected by CCK-8 assays, cell migration was analysed by wound healing assays, and apoptosis was analysed by TUNEL assays. Finally, m6A modification was analysed by methylated RNA immunoprecipitation (MeRIP).Results: Chemotherapy-induced downregulation of the m6A modification is regulated by METTL3 in HR+/HER2- BC. METTL3 knockdown in MCF-7/T47D cells weakened the drug sensitivity of HR+/HER2- BC cells by promoting tumour proliferation and metastasis and inhibiting apoptosis. Mechanistically, CDKN1A was subsequently recognized as a downstream target of METTL3 that activates the AKT pathway and promotes epithelial-mesenchymal transformation (EMT). Moreover, the RNA level of BAX was decreased due to a lower level of m6A modification mediated by METTL3, and apoptosis was inhibited by inactivation of caspase 3/9/8.Conclusion: METTL3 regulates the proliferation, migration, and drug sensitivity of HR+/HER2- BC via activation of the CDKN1A/EMT and m6A-BAX/caspase 9/3/8 signalling pathways, which suggests its role as a potential biomarker for predicting the prognosis of patients with HR+/HER2- BC.
Development and Analysis of Refrigerator using Peltier Effect
Authors: Bhuse Pradnya K , Shinde Abhijeet A , Parkam Pavan S , Pandhare Rohan A , Mandwale Pratiksinh S
Published: December 2021

The development of a refrigerator with some modifications is the need of the era. In this work, development of a refrigerator employing the Peltier effect having volume of cooling as 3.6 cubic meters with dimensions 1.45m x 1m x 2.48m. is reported. The On/off controls are used in order to meet the sufficient refrigeration effect at the required tolerance of temperature. The performance of the device is tested by studying the cooling of a litre of water. The temperature was analysed from room temperature to a certain degree on minus side. The controls were reported to be efficient and given noteworthy performance.
Number Recognition System of Real time Indian Sign Language
Authors: Shaikh Saliya S , Patel Akram A , Pawar Pravadha Deshmukh , Shaikh Rubana P
Published: December 2021

Too many research has been done in the field of Human Computer Interaction (HCI). One of the system called Hand Gesture Recognition (HGR) gives solution to build the HCI systems. Now a days, computer is used as a interpreter between humans. The proposed system is used to recognize the real time static hand gesture of Indian sign language number system zero to nine. In this paper we propose a system for hand gesture recognition which is simple and fast. Based on the proposed algorithm, this system can automatically convert the input hand gesture into the text and audio. The system first capture the image of hand gesture shown by user using a simple webcam then using our proposed algorithm it recognize the gesture. This system can use for real time application due to the use of simple logic condition applied to recognize the gesture. The proposed system is size invariant and implemented using OpenCV.
5G Technology Evolutions
Authors: Joshi Shreyas , Zadbuke Sohan , Kumbar Nagesh , Malshette Sanket , Gurav Vrushali
Published: December 2021

5G technology has number of existing generations of wireless technologies in terms of their portal, efficiency, effectiveness, and cost-benefit analysis. The paper puts a focus on the evolution and development of various generations of mobile wireless technology along with their significance and advantages of one over the other. From past several decades, mobile wireless technologies have experience 4 or 5 generations of technology revolution and evolution, namely from 1G to 4G. The Current research in mobile wireless technology concentrates on promoting the implementation of LTE technology and 5G technology. At present, the term is not officially used. In 5G, the research on the development of World Wide Wireless internet access (WWW), Dynamic adhoc Wireless Networks (DAWN) and Real Wireless World. In this paper, we focusa new network architecture for the next-generation of mobile networks, 5G. In this architecture, the mobile device will have the ability to get to the Radio Access Technology - RAT based on certain user-defined criteria.
Steganographic Data Hiding in QR Codes
Authors: Jagtap Shilpa , Mudegaonkar J L
Published: December 2021

In the era of technological development, data transfer over internet is playing vital role in communication. Now a days use of internet became common and it is necessary to secure the transmission of data in the form of protecting information systems from unauthorized access, use, disruption, modification, recording or destruction. There various methods available for data security, like cryptography and steganography. Steganography is the technique in which data gets hide behind any other information and it becomes difficult for unauthorized user to detect it. QR code is the trademark for a type of matrix barcode consisting of the black square modules arranged in a square grid on a white background. Any imaging devices such as camera, scanner are used for reading the code. In this article we are discussing different technologies that can be used for steganography along with steganography using QR codes.
Automatic National Anthem Playing Unit using RTC & Microcontroller
Authors: Lambe Somnath M , Karande Kailash J
Published: December 2021

As all school, begins on time and if we could play automatic national anthem then it gives energy throughout a day, feels energetic whole day. As we plays it manually there should be always a person is required to turn ON/OFF media player. This manual method is hectic and it encouraged us to play it automatically. So this motivated us to design a system where national anthem plays on predefined time after playing of national anthem it should be automatically stops the playing. So considering these parameter we designed and implemented automatic national anthem player since 2016 and till date it is working smoothly. All required material such microcontroller board, media player, speaker were purchase from local market. Media player main facility of playing again from initial as supply resumes. So, each day national anthem plays from beginning point.
Inventory Management System for Mobile Showroom
Authors: Babar Ajinkya A , Dhanwale Manoj G , Patil Swati , Sale Ratnamala R , Salunke Poonam R
Published: December 2021

Inventory management and supply chain management (SCM) is the backbone of any business operations. With the development of technology and the availability of process-driven software applications, inventory management has undergone revolutionary changes. In any business. Inventory Management System project is developed for making present system paperless and more digitalized [1]. Inventory Management System aims to control manual work in the showroom, to maintain their performance, records and to provide security to stored data. Inventory is always dynamic. Inventory management requires constant and careful evaluation of external and internal factors and control through planning and review. Most organizations have a separate department or job function called inventory planners (IP) who continuously monitor, control, and review inventory and interface with production, procurement, and finance departments. This is a desktop-based application, this is an effective method of Inventory Management System. Based on the collected data and via analyzing records, estimated arrival stock is computed and transmitted to all relevant segments. Inventory Management System will be reduced the manual work. Time is precious in today's fast-moving life. The wastage of time by waiting long in the queue for getting Inventory bill can be avoided by Inventory Management System.
Student’s Performance Prediction Using Hybrid Optimization Algorithm-based Map Reduce Framework
Authors: Bhosale Dipak , Sawane Mahendra
Published: December 2021

Learning analytics (LA) is a growing research area, which aims at selecting, analyzing and reporting student data (in their interaction with the online learning environment), finding patterns in student behaviour, displaying relevant information in suggestive formats; the end goal is the prediction of student performance, the optimization of the educational platform and the implementation of personalized interventions. According to the Society of Learning Analytics Research1, LA can be defined as "the measurement, collection, analysis and reporting of data about learners and their contexts, for purposes of understanding and optimizing learning and the environments in which it occurs". The topic is highly interdisciplinary, including machine learning techniques, educational data mining, statistical analysis, social network analysis, natural language processing, but also knowledge from learning sciences, pedagogy and sociology; up-to-date overviews of the area are provided in. Various educational tasks can be supported by learning analytics, as identified in analysis and visualization of data; providing feedback for supporting instructors; providing recommendations for students; predicting student's performance; student modelling; detecting undesirable student behaviours; grouping students; social network analysis; developing concept maps; constructing courseware; planning and scheduling. Similarly, seven main objectives of learning analytics are summarized in: monitoring and analysis; prediction and intervention; tutoring and mentoring; assessment and feedback; adaptation; personalization and recommendation; reflection.
Review Paper on Grease Lubrication Considering Effect of Solid Contaminant in Lubrication on Vibration Response of Roller Bearing
Authors: Pandhare V. B , Kulkarni S. S
Published: December 2021

Grease lubrication is typically useful to rolling contact bearings. The stableness of grease prevents it from leaking out of any quite of bearing, makes it very easy to use, and should provide it high-quality quality sealing properties. The same stability prevents an optimal lubrication on bearing performance. The majority of the grease is brief of out of the cage of bearing through the primary phase of bearing operation and not dynamically participates within the lubrication process, leaving only a partial quantity available, which is stored within the bearing geometry and on the bearing, shoulders covers or seals. This stored volume strongly determines the remaining lubrication process within the ball bearing. The distribution of this volume is about by the lubricating grease flow, which is extremely complex to know due to the strong nonlinear rheology. Grease process has self healing properties where fresh grease is supplied just in case of film breakdown and self induced heat development. To affect this problem, a non invasive technique like vibration measurement is used for monitoring the performance of machines. This review paper describes the effect of lubricant contamination by solid on the dynamic behaviour of rolling bearing, to figure out the trends within the vibrations of the bearing. Review of paper is made with roller bearings lubricated with contaminated lubricant and healthy grease lubricant. Solid contaminate in three concentration levels and three grain sizes are wont to contaminate the lubricated grease. Vibrations generated during the working of bearing because of contaminants in lubricant are monitor within the terms of the source mean square and crest amplitude values by means of FFT analyzer. The results of contaminant on bearing vibration are considered for both good and defective bearings. The results show remarkable vibration in RMS velocity values on varying the contaminants concentration and grain size.
Water-related sustainability reporting practices amongst South African mining and non-mining corporations
Authors: Latiff Nadia , Marimuthu Ferina
Published: December 2021

Globally, water resource management has emerged as an important research area and is acknowledged as a crucial factor in achieving sustainable development goals. Despite its significance, water-related sustainability disclosures regarding water and water-related risks among companies are alarmingly weak. Many companies are not effectively measuring, managing, and disclosing their water-related risks. Hence, this paper aims to analyze water-related reporting and disclosure requirements of a sample of ten South African mining and non-mining companies with a high water profile, listed on the JSE Socially Responsible Investment Index. The companies’ level of compliance on water disclosure was assessed based on their reporting in the integrated and or annual reports. The findings revealed that sampled five mining companies performed poorly in terms of disclosure across the frameworks of awareness, disclosure, management, and leadership. On the other hand, the selection of five non-mining companies grasped the severe effect of the water crisis on their businesses and performed better in all the framework categories. The average score for the selection of mining companies was 65% compared to the 93% for the non-mining companies. Stakeholders need to focus on water governance processes that require improvement to enable the stakeholders to make better decisions on water management; subsequently, this is an area that needs to be addressed in future research.
A Green Analytical Method Using Polyurethane Foam for The Extraction and Determination of Lauryl Ether Sulfate in Personal Care Hygiene Products
Authors: Müzel Felipe , Rossini Eduardo , Pezza Helena
Published: December 2021

A green methodology was developed for the extraction and determination of lauryl ether sulfate in raw materials and commercial liquid soap and shower gel samples. The method avoids the use of organic solvents, offering a simple, cheap, and safe analysis. The methodology is based on the sorption of an ionic pair consisting of a cationic dye and an anionic surfactant onto polyurethane foam. The experimental variables were optimized by chemometry to obtain the conditions that maximized extraction of the ionic pair. Digital imaging and spectrophotometry were used for quantification in the linear concentration range from 10.0 to 100 mg L-1. The limits of detection and quantification were, respectively, 2.71 and 9.28 mg L-1 for digital imaging, and 1.74 and 5.83 mg L-1 for spectrophotometry. The methods showed good results when applied to commercial samples, with recoveries in the range 96.8-103%.
PSO optimum control strategy of 7 degrees of freedom semi-active suspensions
Authors: Qiao Jubin , Choi Yeonsung , Yang Fuqiang
Published: December 2021

The performance of vehicle body vibration and ride comfort of active or semi-active suspension with proper control is better than that with passive suspension. It is important to use simple, reliable, effective and low-cost optimal control methods to control the vehicle suspension. An important issue in the optimal control of vehicle semi-active suspension is to determine the weighting coefficient reasonably. This paper established a whole-car model of semi-active suspension systems with 7 degrees of freedom in Matlab, built optimum control system with system function, and then optimized the weight of control system by Particle Swarm Optimization (PSO) [1]. The results show that under different road input, the seven-degree-of-freedom control model for the whole vehicle controlled by particle swarm optimization algorithm can obtain better control effect, and effectively improve the comprehensive performance of the semi-active suspension system, both the vehicle's ride comfort and handling stability.
Methylene blue removal using prepared activated carbon from grape wood wastes: adsorption process analysis and modeling
Authors: Mousavi Seyyed Alireza , Shahbazi Davood , Mahmoudi Arezoo , Darvishi Parastoo
Published: December 2021

An adsorption study has been conducted for activated carbon obtained from grape wood wastes to assess their capability to remove methylene blue (MB) from the aqueous solutions. The properties of prepared activated carbon were characterized using FTIR, BET and SEM analyses. The effects of independent variables such as initial concentration of MB (100–500 mg L−1), initial pH of solution (3–11), adsorbent dosage (0.25–12.25 g L−1) and contact time (10–90 min) on the MB adsorption have been optimized using response surface methodology. The highest MB removal efficiency was 98% when pH, MB and adsorbent dosage were 11, 100 mg L−1 and 12.25 g L−1, respectively. The experimental data have been tested using Langmuir and Freundlich isotherm models, and the achieved data were fully fitted with the Langmuir model (R2 = 0.99), which indicates the monolayer adsorption. The adsorption kinetics were followed by the pseudo-second-order model with R2 of 0.99. This prepared activated carbon as a low-cost and eco-friendly adsorbent can be used widely for water and wastewater treatment.
ENTRE O REAL E O FICCIONAL: Intervenção Urbana “A Menina Morta e Nua”
Authors: Gasperi Marcelo Eduardo Rocco
Published: December 2021

O presente artigo faz uma breve análise acerca da intervenção “A Menina Morta eNua”, criada pelo grupo de pesquisa “Transeuntes: Estudos sobre Performance”,da Universidade Federal de São João del-Rei (UFSJ). Partindo do conto“Rremembranças da menina de rua morta nua” de Valêncio Xavier (2006), estaação consistiu, basicamente, em uma exposição de fotos de uma menina (que forasupostamente espancada e morta), enquanto um performer leiloava seus objetospessoais aos passantes nas ruas. Esta pesquisa integra parte da tese de doutoradodo autor deste trabalho.
¿Es la interpretación el punto de encuentro entre teatro, canto y danza?
Authors: Belieres Patricia , Cancela Alejandro
Published: December 2021

participamos del Intercambio Latinoamericano de Teatro Ritual en la Universidade Federal do Rio Grande do Norte (UFRN), en la cálida ciudad de Natal, Brasil. Fuimos invitados por el Dr. Robson Haderchpek gracias a un encuentro causal en la fría Viena en febrero de 2015. Reinhard Flatischler, el creador del método TaKeTina, dictaba un interesante seminario en la Universidad de Música y Arte Dramático de Viena. Patricia observó un cuerpo danzar de manera particular y pensó: “Este muchacho no es europeo”. Dicho y hecho: al finalizar la última clase, se dio el encuentro entre Argentina y Brasil. El muchacho danzante resultó ser Robson y sin mediar palabras, se fundieron en un abrazo latinoamericano. Mientras todos preparaban sus cosas para retirarse, se generó un vínculo por las coincidencias en las líneas de trabajo - basadas en los cuatro elementos - que cada uno realizaba en su país: intercambiaron música del Brasil y el libro “El cantante popular y la interpretación”.
Ogum
Authors: Júlia Barbosa Fernanda , Santana Fernando
Published: December 2021

Trata-se da dramaturgia do espetáculo Ogum - Deus e homem, que por meio da escolha de sete lendas da mitologia desta divindade yorubana, narra-se a trajetória de Ogum. Além de senhor da guerra, Ogum é patrono da tecnologia e protetor da humanidade, essas são características que são evidenciadas no texto.
Microperformances e experiências estelares:
Authors: Ligiéro Zeca
Published: December 2021

Microperformances e experiências estelares: o vivido no relembrado - A partir da sua história pessoal, o autor analisa o impacto das mais distintas performances que o atravessaram desde a tenra idade vivida no interior do norte fluminense. Algumas se transformaram em lembranças fragmentadas, as quais ele nominou como “microperfomances”; outras, às quais foi exposto e que o marcaram profundamente ao longo do seu trabalho criativo ele as conceituou como “experiências estelares”. A partir destas duas definições é proposto um entendimento sobre a importância das performances culturais na percepção sobre tradições, suas hermenêuticas e suas reais contribuições ao desenvolvimento das performances artísticas. Como contraponto ao vivido e ao relembrado, o autor aponta o pensamento hegemônico incutido na memória social do brasileiro. o qual denomina como “recursos coloniais hospedeiros”.
Análise dos Parâmetros Curriculares Nacionais para o Ensino de História
Authors: Barreto Raylane Andreza Dias Navarro , Silva Tayanne Adrian Santana Morais da , Nascimento Raquel Barreto
Published: December 2021

O presente estudo trata-se de uma análise sobre o uso de fontes históricas em sala de aula segundo a perspectiva dos Parâmetros Curriculares Nacionais para o ensino de História. Primeiramente, nos propomos a tecer uma análise acerca da perspectiva de utilização das fontes históricas apontadas pelos PCN’s, buscando localizar a elaboração deste documento em um contexto de influência da Escola dos Annales e de construção de um Brasil democrático. Em seguida, apontamos uma discussão teórica a respeito do uso de fontes em sala de aula, à luz dos estudos dos autores Albuquerque Jr. (2012), Caimi (2008), Fico (2012), Pereira e Seffner (2008). Por fim, apontamos as possibilidades do uso da Capoeira como fonte histórica com base nas recomendações dos PCN’s de História.
Sleep Markers in Psychiatry: Do Insomnia and Disturbed Sleep Play as Markers of Disrupted Neuroplasticity in Mood Disorders? A Proposed
Model
Authors: Palagini Laura , Geoffroy Pierre Alexis , Riemann Dieter
Published: December 2021

Introduction:

Since insomnia and disturbed sleep may affect neuroplasticity,
we aimed at reviewing their potential role as markers of disrupted neuroplasticity involved
in mood disorders.

Method:

We performed a systematic review, according to PRIMA, on PubMed, PsycINFO
and Embase electronic databases for literature regarding mood disorders, insomnia,
sleep loss/deprivation in relation to different pathways involved in the impairment of neuroplasticity
in mood disorders such as (1) alterations in neurodevelopment (2) activation
of the stress system (3) neuroinflammation (4) neurodegeneration/neuroprogression, (5)
deficit in neuroprotection.

Results:

Sixty-five articles were analyzed and a narrative/ theoretical review was conducted.
Studies showed that insomnia, sleep loss and sleep deprivation might impair
brain plasticity of those areas involved in mood regulation throughout different pathways.
Insomnia and disrupted sleep may act as neurobiological stressors by over-activating
the stress and inflammatory systems, which may affect neural plasticity causing neuronal
damage. In addition, disturbed sleep may favor a deficit in neuroprotection hence
contributing to impaired neuroplasticity.

Conclusions:

Insomnia and disturbed sleep may play a role as markers of alteration in
brain plasticity in mood disorders. Assessing and targeting insomnia in the clinical practice
may potentially play a neuroprotective role, contributing to “repairing” alterations in
neuroplasticity or to the functional recovery of those areas involved in mood and emotion
regulation.
Complications in Patients with Cardiac Penetrating Trauma
Authors: Ahmadinejad Mojtaba , Ahmadinejad Izadmehr , Maghsoudi Leila Haji , Soltanian Ali , Safari Mehdi
Published: December 2021

Background:

Cardiac penetrating trauma is a medical emergency that mostly affects young people. Based on the type of injury and associated complications, it can present as a surgical challenge and can lead to mortality.

Objective:

The aim of this study is to evaluate the complications of penetrating heart trauma among patients referred to Shahid Madani Hospital.

Methods:

In this retrospective descriptive study, the data of penetrating cardiac trauma patients referred to Shahid Madani hospital, Karaj, Tehran, from 2016-2019, were investigated. Information, including age, sex, cause of trauma, traumatized area and complications, was extracted and recorded in a data collection form. The data were evaluated statistically using SPSS v18.

Results:

A total of 44 patients were included in the study, where the mean age of the patients was 25 years. 73.3% of these patients were men and 26.7% were women. Knife stab wounds were the most prevalent cause of the trauma, present in 93.3% of patients. 73.3% of the patients had cardiac tamponade and 20% had a pneumothorax. The right ventricle was the most common site of the injury in 46.7% of the patients. A mortality rate of 3.4% was reported in this study.

Conclusion:

The results of this study showed that the highest penetrating heart rate trauma occurred among young people, and the most common cause of the trauma was a knife stab. The most common area of the injury was the right ventricular, and cardiac tamponade was the most common complication.
Validation of a Booklet on the Use of BI-RADS® in Mammography Examination
Authors: Nunes Maria Ivanete , Campo Silvia Amélia Prado Burgos Madeira , Santos Junio Luiz Ayrton , Lago Eliana Campêlo , Almeid Camila Aparecida Pinheiro Landim , Ribeiro Ivonizete Pires
Published: December 2021

Background:

The

Breast Imaging-Reporting and Data System

(BI-RADS

®

) is an international classification developed to systematize breast assessment, exam interpretation, and the preparation of reports of specific breast imaging exams.

Objective:

The objective of this study was to validate with experts a booklet directed to medical and nursing professionals in the Family Health Strategy on the categorization of Breast Imaging Reporting and Data System in order to describe the reports of mammography.

Methods:

This was a technology-validation study of the methodological-development type. The evaluation was performed with 11 experts, including seven radiologists and four mastologists, four men and seven women, with a mean age of 45 years, meantime of being in the profession of 22 years, and an average 15 years of working experience of in the field.

Results:

The individual, mean, and global Content Validity Index (CVI) was calculated. The booklet was validated with a CVI of 0.89. The suggestions of the experts were analyzed, and some of them were implemented for the final version of the booklet.

Conclusion:

The booklet was validated and will contribute significantly to the daily activities of medical and nursing professionals in the Family Health Strategy in relation to the interpretation of the mammographic report and the orientation regarding the referral, agility, and qualification of the patient to the specialized service.
Does Sexual and Emotional Behavior Differ Between Sexual Partners That Do Not Disclose HIV Status?
Authors: de Oliveira Layze Braz , Queiroz Artur Acelino Francisco Luz Nunes , da Silva Oliveira Adélia Dalva , Magalhães Sales Isabela Maria , de Oliveira sena Inara Viviane , dos Santos Jaqueline , de Araújo Telma Maria Evangelista , Mondlane Jose , Reis Renata Karina
Published: December 2021

Objective:

The objective of the study was to analyze whether the disclosure of HIV serological status among sexual partners is associated with differences in sexual affective behavior.

Methods:

Cross-sectional study was carried out with 173 participants in a specialized assistance service on the treatment of people with the Human Immunodeficiency Virus. Data were collected through interviews.

Results:

Our results show that from the participants who did not disclose their HIV status and who were sexually active, most had multiple sexual partners (44.6%), used combined methods of prevention (75.4%), had casual partners (63.0%), used condoms (66.2%), and had sexual intercourse while under the influence of alcohol (56.9%). The variables i.e., number of partners (p = 0.010) and type of relationship (p <0.001) showed statistical differences.

Conclusion:

Sexual affective behavior variables influenced the decision about disclosing HIV seropositivity to sexual partners that establish different forms of sexual partnerships.
Dimensões da justificação no discurso legislativo uma abordagem diacrónica
Authors: Barros Clara
Published: December 2021

this paper I intend to analyse some aspects of the evolution observable in the way the legislative discourse justifies the legal-legislative provisions in legislative texts of different synchronies of the Portuguese language: this is especially apparent when they present statements which contain acts of discourse with justification value.From a comparative and diachronic perspective, I will confront Afonso X’s medieval legislative texts (such as the Portuguese versions of the Primeyra Partida and the Foro Real) with contemporary Portuguese legislative texts. I will attempt to demonstrate that in medieval legislative texts, in addition to the greater extent of the supporting segments, there is also a discursive structure that uses arguments of authority. In Afonso X’s legislative texts royal legislation is conveyed and the Speaker, designated by the first person “we”, is identified with the king, holding a power inherent to this statute. It reaffirms its status as authority and the desirability of royal legislative action and affirms the pragmatic need for the existence of justice by its favourable effect (which is ethically identified with the Common Good).By contrast, contemporary legislative discourse is presented in the third person and this does not designate any individualized subject. The law is stabilized, established in multi-secular institutions and fundamental rights are already guaranteed, and new legislation is generally conjunctural and especially case-by-case legislation. In contemporary legislative formulations there is no discourse of the legitimization of power and the dimension of the supporting segments is smaller.
Velhas e novas classes de formativos e de processos de construção de palavras o caso particular de splintering e de fractocomposição
Authors: Rio-Torto Graça
Published: December 2021

The present study describes the classes of formatives and processes of word construction, such as (i) affixation and composition, the most established and stabilized, (ii) blending/lexical fusion and clipping/shortening, less represented than the previous ones, and (iii) some of the most innovative, such as those operating with splinters. The legitimation of these formatives, with origin in non-morphememic segments that acquire, as a result of reanalysis, morfolexical status, poses the problem of the nature of the processs in which they operate. Once the autonomy from blending is established, the proximity of splintering to affixation and composition is discussed, and the fractocomposition is proposed as the subclass in which splinters can be enrolled, together with other fractoformatives. In order to characterize these formatives, in this study the processes’categorization is based on the ±bound, ±fragmented/splintered and/or ±clipped nature of the formatives.
Demonstratives, definiteness effects and the type-token distinction
Authors: Bosque Ignacio
Published: December 2021

Definiteness effects have been attested in the literature for some DPs complementing HAVE (= English have and their counterparts in other languages). In this paper, which focuses on English and Spanish, demonstrative DPs are shown to be affected by the type-token distinction in HAVE contexts: the internal argument of HAVE receives a type reading in these cases and rejects a to-ken interpretation. The “type restriction on demonstrative DPs” (TRD) is shown to follow from the need for narrow focus NPs complementing HAVE to receive a hearer-new reading, a well-known property of presentational structures. Type readings of demonstrative DPs are shown to meet this condition. Apparent exceptions to the TRD effect include (i) DPs in so-called “remainder contexts”; (ii) structures in which the relevant DP is the subject of a small clause (sometimes with a non-overt predicate); and (iii) structures containing a number of anti-assertive operators. The contexts in (i) are shown to be hearer-new, in spite of being definite. Those in (ii) and (iii) provide DPs which escape the narrow focus interpretation that gives ride to this variety of the definiteness effect.
Deverbal nominalizations without overt suffixation in French
Authors: Sleeman Petra
Published: December 2021

Recent work on argument taking deverbal zero nouns in English has shown that they are more present in that language than was previously thought. In this paper the presence and productivity of argument taking zero-derived nouns in French is investigated. It is shown that to determine which nouns can count as zero nouns, several decisions have to be made. This concerns their gender (do both masculine and feminine nouns have to be included in the research?), the determination of what counts as an argument, the criteria used to determine if a noun is an argument taking noun, the form and category that the base may have. On the basis of the adopted criteria and a dictionary and database research, a corpus of French zero-derived nouns in French is composed and analyzed. The results show that, as in English, zero-derived nouns in French are more productive than was thought.
Removal of Total Coliform and TSS for Hospital Wastewater by Optimizing the Role of Typha Angustifolia and Fine Sand-Gravel Media in Horizontal Sub Surface Flow Constructed Wetland
Authors: Akhmad Abdul Gani
Published: December 2021

This study aims to evaluate the performance of a pilot-scale HSSF-CW utilizing Typha angustifolia and fine sand-gravel media in removing total coliform and TSS from hospital wastewater. Three pilot-scale HSSF-CW cells measuring 1.00 x 0.45 x 0.35 m3 were filled with gravel sand media with a diameter of 5 - 8 mm as high as 35 cm with a submerged media depth of 0.30 m. There were three treatments, namely the first cell (CW1) without plants, the second cell (CW2) was planted with a density of 12 Typha angustifolia plants, and the third cell (CW3) was planted with a density of 24 Typha angustifolia plants. The three HSSF-CW cells received the same wastewater load with total coliform and TSS contents of 91000 MPN / 100 mg and 53 mg / L, respectively, with Hydraulic Loading Rates 3,375 m3 per day. Wastewater was recirculated continuously to achieve the equivalent HSSF-CW area requirement. The experimental results show that the performance of CW3 is more efficient than CW1 and CW2 in total coliform and TSS removal for hospital wastewater. The pollutant removal efficiency at CW3 reached 91.76% for total coliform with one day hydraulic retention time and 81.00% for TSS with two days of hydraulic retention time. This study concludes that the HSSF-CW system using sand-gravel media with a diameter of 5 - 8 mm with a submerged media depth of 0.30 m and planted with Typha angustifolia with a tighter spacing proved to be more efficient in removing total coliform and TSS from hospital wastewater.
Defining the Enablers and Barriers to the Implementation of Large-scale, Health Care–Related Mobile Technology: Qualitative Case Study in a Tertiary Hospital Setting
Authors: Aggarwal Ravi , Visram Sheena , Martin Guy , Sounderajah Viknesh , Gautama Sanjay , Jarrold Kevin , Klaber Robert , Maxwell Shona , Neal John , Pegg Jack , Redhead Julian , King Dominic , Ashrafian Hutan , Darzi Ara
Published: December 2021

Background

The successful implementation of clinical smartphone apps in hospital settings requires close collaboration with industry partners. A large-scale, hospital-wide implementation of a clinical mobile app for health care professionals developed in partnership with Google Health and academic partners was deployed on a bring-your-own-device basis using mobile device management at our UK academic hospital. As this was the first large-scale implementation of this type of innovation in the UK health system, important insights and lessons learned from the deployment may be useful to other organizations considering implementing similar technology in partnership with commercial companies.

Objective

The aims of this study are to define the key enablers and barriers and to propose a road map for the implementation of a hospital-wide clinical mobile app developed in collaboration with an industry partner as a data processor and an academic partner for independent evaluation.

Methods

Semistructured interviews were conducted with high-level stakeholders from industry, academia, and health care providers who had instrumental roles in the implementation of the app at our hospital. The interviews explored the participants’ views on the enablers and barriers to the implementation process. The interviews were analyzed using a broadly deductive approach to thematic analysis.

Results

In total, 14 participants were interviewed. Key enablers identified were the establishment of a steering committee with high-level clinical involvement, well-defined roles and responsibilities between partners, effective communication strategies with end users, safe information governance precautions, and increased patient engagement and transparency. Barriers identified were the lack of dedicated resources for mobile change at our hospital, risk aversion, unclear strategy and regulation, and the implications of bring-your-own-device and mobile device management policies. The key lessons learned from the deployment process were highlighted, and a road map for the implementation of large-scale clinical mobile apps in hospital settings was proposed.

Conclusions

Despite partnering with one of the world’s biggest technology companies, the cultural and technological change required for mobile working and implementation in health care was found to be a significant challenge. With an increasing requirement for health care organizations to partner with industry for advanced mobile technologies, the lessons learned from our implementation can influence how other health care organizations undertake a similar mobile change and improve the chances of successful widespread mobile transformation.
An Innovative App (ExoDont) for Postoperative Care of Patients After Tooth Extraction: Prototype Development and Testing Study
Authors: Krishna Meenakshi , Sybil Deborah , Shrivastava Priyanshu Kumar , Premchandani Shubhangi , Kumar Himanshu , Kumar Pintu
Published: December 2021

Background

The postoperative period is crucial for the initiation of healing and prevention of complications after any surgical procedure. Due to factors such as poor compliance, comprehension, and retention of instructions, and other unaccounted factors, the objectives of postoperative care are not always achieved. Therefore, an Android-based mobile health app (ExoDont) was developed to ensure a smooth postoperative period for patients after a dental extraction. The ExoDont app delivers reminders for postoperative instructions and drug intake at defined intervals, thus fostering self-reliance among patients in taking their prescribed dose of medication.

Objective

The aim of this study is to design, develop, and validate ExoDont, an innovative app for improved adherence to postoperative instructions after tooth extraction.

Methods

A postoperative treatment protocol was developed by a team of oral and maxillofacial surgeons and general dentists, following which the clinical and technological requirements of the app were determined along with the software engineers, graphic designers, and applications architect in the team. ExoDont was developed to provide timely reminders for medication and postoperative care. The app was field tested and validated using the User Version of the Mobile Application Rating Scale.

Results

The ExoDont software design was divided into a 3-level architecture comprising a user interface application, logical layer, and database layer. The software architecture consists of an Android-based ExoDont app for patients and a web version of the admin panel. The testing and validation of the ExoDont app revealed that Perceived Impact received the highest mean score of all rated components (mean 4.6, SD 0.5), while Engagement received the lowest mean score (mean 3.5, SD 0.8).

Conclusions

The testing and validation of the app support its usability and functionality, as well as its impact on users. The ExoDont app has been designed, keeping the welfare of patients in view, in a user-friendly manner that will help patients adhere to the prescribed drug regimen and ensure easy and efficient dissemination of postoperative instructions. It could play an instrumental role in fostering compliance among patients and significantly decrease the complication rate following dental extractions.
Administration of Parenteral Vitamin C in Patients With Severe Infection: Protocol for a Systematic Review and Meta-analysis
Authors: Agarwal Arnav , Basmaji John , Fernando Shannon M , Ge Fang Zhou , Xiao Yingqi , Faisal Haseeb , Honarmand Kimia , Hylands Mathieu , Lau Vincent I , Lewis Kimberley , Couban Rachel , Lamontagne François , Adhikari Neill KJ
Published: December 2021

Background

Severe infections are characterized by inflammation and oxidative damage. Ascorbic acid (vitamin C) administration may attenuate oxidative damage and, in turn, reduce vascular endothelial injury in pulmonary and systemic vasculature.

Objective

We aim to describe a protocol for a living systematic review that will evaluate the effectiveness and safety of parenteral vitamin C administration in adults with severe infections, including those with COVID-19.

Methods

We searched Ovid MEDLINE, Embase, CINAHL, the Centers for Disease Control and Prevention COVID-19 database, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from inception to March 30, 2021, for randomized controlled trials evaluating parenteral vitamin C versus no parenteral vitamin C in hospitalized adults with severe infection. Eligible studies will include at least 1 arm involving any dose of parenteral vitamin C alone or in combination with other cointerventions and at least 1 arm not involving parenteral vitamin C. The primary outcomes of interest will include in-hospital, 30-day, and 90-day mortality. Title and abstract screening, full-text screening, data extraction, and risk of bias evaluation via a modified Risk of Bias 2.0 tool will be conducted independently and in pairs. We will perform random effects modeling for meta-analyses, in which study weights will be generated by using the inverse variance method. We will assess certainty in effect estimates by using the Grading of Recommendations Assessment, Development and Evaluation methodology. Meta-analyses will be updated iteratively as new trial evidence becomes available.

Results

Among the 1386 citations identified as of March 30, 2021, a total of 17 eligible randomized controlled trials have been identified as of September 2021. We are in the process of updating the search strategy and associated data analyses.

Conclusions

The results will be of importance to critical care physicians and hospitalists who manage severe infection and COVID-19 in daily practice, and they may directly inform international clinical guidance. Although our systematic review will incorporate the most recent trial evidence, ongoing trials may change our confidence in the estimates of effects, thereby necessitating iterative updates in the form of a living review.

Trial Registration

PROSPERO CRD42020209187; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=209187

International Registered Report Identifier (IRRID)

RR1-10.2196/33989
Nghiên cứu ứng dụng công nghệ đất ngập nước kiến tạo sử dụng thực vật xử lý nguồn nước mặt ô nhiễm
Authors: Nguyễn Minh Kỳ , Nguyễn Công Mạnh , Phan Văn Minh , Nguyễn Nguyễn Tri Quang Hưng , Phan Phan Thái Sơn
Published: December 2021

Nghiên cứu ứng dụng công nghệ đất ngập nước kiến tạo có dòng chảy đứng để xử lý nguồn nước mặt ô nhiễm kênh D ở thị xã Thuận An phục vụ canh tác nông nghiệp đã được tiến hành. Hai yếu tố tác động đã được nghiên cứu gồm (1) cây trồng và (2) tải nạp thủy lực. Cỏ sậy (Phragmites australis L.) và cỏ vertiver (Vertiveria zizanioides L.) được sử dụng trong nghiên cứu với đối chứng là không trồng cây. Các tải nạp thủy lực được thử nghiệm lần lượt gồm 500, 1000 và 1500 mL/phút/m2. Kết quả nghiên cứu cho thấy công nghệ đất ngập nước kiến tạo với mức tải nạp thủy lực 500 mL/phút/m2 có hiệu quả xử lý tốt nhất với lần lượt: hàm lượng BOD5 của nước sau xử lý là 10,6±0,8 mg/L, hiệu quả xử lý 94,4±0,4%; COD là 24,3±2,7 mg/L, hiệu quả xử lý 90,6±0,8%; TSS là 23,6±0,2 mg/L, hiệu quả xử lý 84,4±0,6%. Quá trình phân tích thống kê cho thấy không có sự khác biệt về hiệu quả xử lý BOD5, COD, TSS giữa các loại cây trồng (P>0,05). Tuy nhiên, mức độ loại bỏ thông số vi sinh fecal coliform chỉ ra tác động tích cực của các loại cây trồng trong mô hình đất ngập nước kiến tạo. Trong khi đó, yếu tố tải nạp thủy lực có tác động rõ rệt đến hiệu quả xử lý BOD5, COD, TSS (P<0,05). Từ đó cho thấy mô hình nghiên cứu phù hợp với xu hướng thân thiện môi trường và đáp ứng nhu cầu phát triển nông nghiệp bền vững.
Tính chất điện tử của dãy nano penta-graphene biên răng cưa sai hỏng dạng khuyết
Authors: Nguyễn Thành Tiên , Lê Võ Phương Thuận , Đào Hoàng Chương , Võ Thị Ngọc Huyền
Published: December 2021

Trong bài báo này, tính chất điện tử của các dãy penta-graphene dạng răng cưa (SSPGNR) sai hỏng dạng khuyết (DSSPGNRs) được nghiên cứu bằng cách tính năng lượng liên kết, cấu trúc vùng điện tử và mật độ trạng thái bởi phương pháp nguyên lý ban đầu. Ba kiểu khuyết được khảo sát trong nghiên cứu này là khuyết đơn nguyên tử C1, C2 và khuyết đồng thời hai nguyên tử C2. Kết quả nghiên cứu cho thấy DSSPGNR có độ rộng vùng cấm giảm đáng kể so với mẫu không khuyết. Trong đó, DSSPGNRs  khuyết đồng thời hai nguyên tử C2 có độ rộng vùng cấm giảm nhiều hơn so với DSSPGNRs khuyết đơn nguyên tử. Kết quả nghiên cứu này cung cấp thông tin quan trọng cho việc phát triển ứng dụng penta-graphene trong lĩnh vực vi điện tử.
Xây dựng mô hình dự báo chuỗi thời gian cho dữ liệu khoảng dựa vào bài toán phân tích chùm
Authors: Võ Văn Tài , Trần Ngọc Nhã Hân , Từ Ngọc Thảo
Published: December 2021

Nghiên cứu này đề xuất sử dụng khoảng cách chồng lấp trong đánh giá sự tương tự của hai khoảng. Dựa trên khoảng cách này và bài toán phân tích chùm cho các phần tử rời rạc, mô hình dự báo cho chuỗi thời gian với dữ liệu khoảng được xây dựng trong nghiên cứu. Mô hình đề nghị đã trình bày cụ thể các bước và được minh hoạ bởi một ví dụ số. Nó cũng áp dụng trong dự báo đỉnh mặn tại các trạm đo trên các con sông chính của tỉnh Cà Mau. Mô hình đề nghị có thể thực hiện nhanh chóng bởi một chương trình được thiết lập trên phần mềm Matlab.