bluuebunny/crossref_metadata_2025 huggingface dataset:
Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis
Authors: Bah Germanus S. , Schneckener Sebastian , Hahnel Steffen R. , Bayang Nicolas H. , Fieseler Helena , Schmuck Gabriele M. , Krebber Ralph , Sarr Anouk , Terjung Carsten , Ngangyung Henrietta F. , Ekale David D. , Mfopit Youssouf M. , Rufener Lucien , Graham-Brown John , Tanya Vincent N. , Glenschek-Sieberth Martin , Kulke Daniel , Makepeace Benjamin L.
Published: June 2021

Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely on ivermectin, which suppresses symptoms caused by the first-stage larvae (microfilariae) but does not kill the long-lived adults. Here, we evaluated emodepside, a semi-synthetic cyclooctadepsipeptide registered for deworming applications in companion animals, for activity against adult filariae (i.e., as a macrofilaricide). We demonstrate the equivalence of emodepside activity on SLO-1 potassium channels in Onchocerca volvulus and Onchocerca ochengi, its sister species from cattle. Evaluation of emodepside in cattle as single or 7-day treatments at two doses (0.15 and 0.75 mg/kg) revealed rapid activity against microfilariae, prolonged suppression of female worm fecundity, and macrofilaricidal effects by 18 months post treatment. The drug was well tolerated, causing only transiently increased blood glucose. Female adult worms were mostly paralyzed; however, some retained metabolic activity even in the multiple high-dose group. These data support ongoing clinical development of emodepside to treat river blindness.
Brand experience dimensions influencing age-wise lingerie purchase motivation: A study of Indian women consumers
Authors: Singh Neetu , Jena Binaya Bhusan , Chandra Rahul
Published: June 2021

This article aims to evaluate age-related brand experience influencing the lingerie buying behaviours of Indian women consumers by using the brand experience scale developed by the authors. It categorizes brand experience using four dimensions: ‘sensory, affective, intellectual and behavioural’. In order to categorize and analyse the brand experience of Indian lingerie-buying consumers, a questionnaire based on the twelve-item brand experience scale developed by Brakus, Schmitt and Zarantonello was administered to a sample of 1392 women consumers aged between 18 and 44 years, educated to a minimum of Grade 12 level and residing in metropolitan and non-metropolitan areas of India. The results were then tabulated to ascertain the most influential dimensions. The results showed that Indian lingerie-buying consumers can be divided into two groups aged 18–29 and 30–44 years, based on their lingerie-buying brand experiences. The two groups also showed that different experience dimensions influenced their lingerie-buying motivation and brand loyalty. Since the existing literature on lingerie studies focuses predominantly on fit and design issues, this study is of paramount importance to consumers, who will be able to identify dimensions other than functional factors influencing their purchase behaviour. Manufacturers, retailers and marketers will also benefit from the same by being able to create an optimum brand experience for women consumers via their products and offerings, leading to brand satisfaction and brand loyalty.
Pedro José Aldazabalen euskal testuak: edizioa eta filologia-gaiak
Authors: Zuloaga San Román Eneko
Published: June 2021

Lan honetan Pedro José Aldazabal idazle gipuzkoarraren euskal lanen edizio kritikoa aurkezten da: hala Aldazabalek berak idatzitako testuena nola bestek idatzi eta Aldazabalek bere lanetan jasotakoena. Testu horien edizio kritikoa aurkezteaz gain, Euskal Erria aldizkarian (1887) eta ConTAVen (Sarasola 1983) XVII. mendekotzat joaz argitaratutako Itziarko Ama Birjinaren omenezko kopla-sorta egiazki Aldazabalena dela defendatzen da; bestalde, Aldazabalen bederatziurrena XIX. mendean berrargitaratu zuen Gorostegik, hizkerako hainbat ezaugarri eraldatuta: bi testuen arteko alderaketa ere aurkezten da, literatur gipuzkeraren bilakabidea eta XVIII-XIX. mendearen amaierako hautu linguistikoak hobeto ezagutzeko lagungarri izan daitekeelakoan.
La soltería virtuosa: dignidad, utilidad y el discurso sobre el celibato femenino en la España contemporánea (1820-1950)
Authors: Camino Alejandro , Martykánová Darina
Published: June 2021

La soltería femenina fue a menudo objeto de sorna y de ridículo en la cultura popular y en el debate intelectual en la España contemporánea, algo que se ha interpretado como un signo de rechazo en favor del matrimonio y/o de miedo a su potencial subversivo. Sin embargo, mostraremos que era un estado que gozaba de alto grado de aceptación y respetabilidad en la sociedad española de la época siempre y cuando se cumpliesen una serie de requisitos. Si bien la historiografía ha ido construyendo la noción de que fundamentalmente existieron dos estados dignos para una mujer en las construcciones de género dominantes en la cultura política católica, la soltería religiosa y el matrimonio, existió una tercera vía defendida públicamente: la soltería laica. Para analizar estas cuestiones, hemos optado por una exploración a largo plazo de la inestable jerarquía de prestigio que existía entre los distintos modelos de feminidad.
Discursos sobre nación y patria en el anarquismo español de entre siglos
Authors: Barrio Alonso Mª Angeles
Published: June 2021

La doble identidad clase/nación no ha sido un objeto de conocimiento privilegiado de la historiografía social, aunque haya constancia de que, como procesos de construcción identitaria, operen habitualmente en paralelo. La idea de clase no era una cuestión central en el pensamiento anarquista cuyo discurso emancipador, universalista y cosmopolita, se dirigía a la humanidad en su conjunto y no sólo a los trabajadores. Sin embargo, la idea de nación, como la de patria, y sus expresiones derivadas, nacionalismo y patriotismo, formaban parte del discurso anarquista de impugnación del Estado y sus instituciones. Pero en ambos casos, la cuestión de las identidades adquiría formulaciones muy diversas e, incluso, aparentemente contradictorias.
Una nutrix en un epígrafe funerario procedente de Burguillos del Cerro (Badajoz, España)
Authors: Paniego Díaz Pablo
Published: June 2021

Se presenta un epígrafe funerario localizado en el casco urbano de Burguillos del Cerro (Badajoz, España) en el que probablemente se mencione una nutrix.
Evaluation of Environmental Awareness of University Students: the Case of the University of Presov, Slovakia
Authors: Novotný Roman , Huttmanová Emília , Valentiny Tomáš , Kalistová Anna
Published: June 2021

At present, all components of the environment are burdened by human activities. These human activities have caused many environmental problems, and without appropriate measures, they will have other far-reaching consequences in the future, which may be irreversible. One of the basic measures for the sustainable future of the environment and human society is to build the environmental awareness of the population. In addition to other entities, universities and their students and graduates have an important role in this process. The study focuses on the evaluation and comparison of environmental awareness and its factors among students of the University of Presov in Presov, Slovakia. Based on the results of this research, social networks and the internet are used as the main source of environmental information and should be used as a means of raising environmental awareness among students. The students of the University of Presov achieved high environmental awareness within the cognitive and emotional factors of environmental awareness, but they achieved only moderate environmental awareness within the behavioral factor. There were no significant differences in the level of environmental awareness between male and female students at the University of Presov. From the point of view of the group of study fields variable, significant differences were found in the emotional and behavioral factors of environmental awareness, with students of "Humanities" and "Natural Sciences, Mathematics and Informatics" achieving the highest scores and students of "Social, Economic and Legal Sciences" and "Healthcare" achieving the lowest scores.
Optimization of saccharification prospective from starch of sweet potato roots through acid-enzyme hydrolysis: structural, chemical and elemental profiling
Authors: Jagatee Suman , Priyadarshini Sonali , Pradhan Chinmay , Sahoo Santi L. , Mohanty Rama C. , Ram Shidharth S. , Sudarshan Mathummal , Teka Tilahun A. , Rout Jyoti R.
Published: June 2021

The sweet potato root, a potent source of starch which is being considered as an efficient alternative for fuel ethanol production in recent times. The starchy substrate needs to be subsequently dextrinized and saccharified so as to enhance the utilization of its carbohydrates for ethanol production. In the present investigation, acid-enzyme process was conducted for the dextrinization and saccharification of sweet potato root flour (SPRF). The best optimized condition for dextrinization was achieved with an incubation period of 60 min, temperature 100 ºC and 1M HCl. However, for saccharification, the best result was obtained with an incubation of 18 h, pH 4, temperature 65 ºC and 1000 U concentration of Palkodex®. After the dextrinization process, maximum concentrations of total sugar and hydroxymethylfurfural (HMF) [380.44 ± 3.17 g/kg and 13.28 ± 0.25 mg/g, respectively] were released. Nevertheless, after saccharification, 658.80 ± 7.83 g/kg of total sugar was obtained which was about 73% more than that of dextrinization. After successful dextrinization and saccharification, the structural, chemical and elemental analysis were investigated using techniques such as scanning electron microscopy (SEM), Fourier-transforms infrared spectroscopy (FTIR) and energy-dispersive X-ray fluorescence spectrophotometer (EDXRF), respectively. Effective hydrolysis was demonstrated in thin layer chromatography (TLC) where the HCl was able to generate monomeric sugar such as glucose and maltose. On the other hand, only glucose is synthesized on the mutual effect of HCl and Palkodex®. The SEM findings indicate that the rough structure of both dextrinized and saccharified sample was gained due to the vigorous effect of both acid and enzyme subsequently. The saccharified SPRF when subjected to fermentation with Saccharomyces cerevisiae and Zymomonas mobilis separately, it was observed that Z. mobilis produced more stretching vibration of –OH than S. cerevisiae, which evidenced the better production of bioethanol. Additionally, evaluation of the influence of S. cerevisiae and Z. mobilis through elemental analysis revealed upsurge in the concentrations of S, Cl, Ca, Mn, Fe and Zn and decline in the concentrations of P, K and Cu in the fermented residue of S. cerevisiae and Z. mobilis, however, Z. mobilis showed little more variation than that of S. cerevisiae.
MANAGEMENT OF MUSCULOSKELETAL CONDITIONS IN RURAL SOUTH AUSTRALIA: A RANDOMISED CONTROLLED TRIAL
Authors: Dent E. , Hoon E. , Karnon J. , Kitson A. , Dollard J. , Newbury J. , Harvey G. , Gill T. , Beilby J.
Published: June 2021

With age, the prevalence of musculoskeletal conditions increases markedly. This rural-based study determined the benefits of two approaches for managing musculoskeletal conditions: a multiple-component ‘Self-management Plus’ intervention, and usual care. The intervention combined self-management education with physical activity and health professional support. 6-month outcomes included: Clinical Global Impression-Improvement Scale (CGI-IS) and Quality of Life (QoL). A total of 145 people were recruited; mean (SD) age was 66.1 (11.1) and 63.3 (10.9) years for intervention and control groups respectively. The intervention resulted in greater improvements in global functioning (CGI-IS mean (SD) = 3.2 (1.3)) than usual care (CGI-IS mean (SD) = 4.2 (1.5)). There was no difference in QoL improvement between study groups. A multiple-component ‘Self-management Plus’ intervention had a positive effect on physical functioning for older adults with musculoskeletal conditions. However, recruitment and retention of participants was problematic, which raises questions about the intervention’s feasibility in its current form.
Chronic Intestinal Pseudo-Obstruction Due to Incidentally Found Thymoma
Authors: Castaneda Daniel , Miret Rafael , Rajagopalan Rajaganesh , Castillo Michael , Gonzalez Adalberto , Castro Fernando
Published: June 2021

Chronic intestinal pseudo-obstruction is a severe gastrointestinal tract disorder mimicking a bowel obstruction with no mechanical causes. Our patient presented with bowel obstruction symptoms, and a thymoma was incidentally found during the diagnostic workup. After failing conservative management, the patient underwent exploratory laparotomy that showed negative results for a mechanical cause of obstruction. Laboratory workup was suggestive of paraneoplastic syndrome, and the patient was started on steroids and pyridostigmine course with symptom resolution. Thus, in patients with chronic intestinal pseudo-obstruction, paraneoplastic syndrome should be considered in the differential diagnosis.
Features of the microbial landscape of patients' wounds at different periods of existence
Authors: Yarets Y
Published: June 2021

Aim: to analyze the results of a microbiological diagnostics of wound swabs in patients with wounds of different duration. Material and methods. The results of bacteriological swabs of 405 wound samples from acute wounds (AW, up to 3 weeks, n=176) and chronic wounds (CW, more than 3 weeks, n=229) were analyzed. Results. Differences were found between the groups in the frequency of obtaining negative swabs (in AW – 24.7% [18.6; 30.9] cases), detection of monocultures (in AW – 50.9% [45.3; 56.5] cases) and microbial associations (in CW – 42.0% [35.4; 48.6]). Gram(+) bacteria – 73.1% and 62.1% (Staphylococcus spp., E. faecalis, Streptococcus gr. viridans) were dominant in wounds; Gram(-) bacteria (23.8% in AW and 33.6% in CW), represented by Enterobacterales, Pseudomonas and Acinetobacter, in CW were characterized by a wider species diversity. Only Gram(+) bacteria were found in AW up to 1 day of the existence; a change in the qualitative composition of microflora was manifested starting from the 10th day of the existence of wounds in the form of the appearance of Enterobacterales, Pseudomonas and Acinetobacter. The prevalence of methicillin-resistant S. aureus and coagulase-negative staphylococci strains was 52% and 54% for AW, 42% and 72% for CW, respectively. E. faecalis showed a high level of resistance to aminoglycosides and fluoroquinolones in all the wounds (>50% of isolates). Gram(+) bacteria were completely susceptible to vancomycin, teicoplanin, linezolid, and tigecycline. The sensitivity of A. baumannii and P. aeruginosa to carbapenems in all cases was high – 69% and 74%, to colistin – 100%. The sensitivity to aminoglycosides – amikacin, tobramycin in P. aeruginosa was 76% and 78%, in A. baumannii – 48% and 59%, respectively. K. pneumoniae showed complete sensitivity to carbapenems. Other Enterobacteriaceae were less resistant than K. pneumoniae. Conclusion. The results of a microbiological diagnostics of wound swabs made it possible to determine the qualitative structure of microflora and its differences depending on the duration of wound existence. The data obtained are the basis for further research, allowing to establish priority pathogens that disrupt the process of wound healing and are the cause of the formation of chronic wounds.
Perencanaan Partisipatif Tanggap Darurat Bencana Tsunami Di Pesisir Selatan Watulimo, Trenggalek
Authors: Usman Fadly , Hariyani Septiana , Shoimah Fadhilatus
Published: June 2021

The research aims to mapping the tsunami-prone areas in Watulimo District using numerical simulation methods and spatial analysis as well as compiling tsunami response planning by determining shelters and evacuation routes in a participatory manner according to the characteristics of residents local wisdom of Watulimo District using weighting analysis and network analysis with ArcGIS. The most prone area to tsunami is Prigi Village because it has the lowest topography compared to the other two villages. Determination of shelter is carried out by considering the building function, number of floors, building area, building capacity, distance from the coastline, location from the road, and building construction. Public facilities with the number of floors >1 such as flat, trade facilities; religious facilities; educational facilities; government facilities; as well as health facilities in Watulimo District can be used as shelters during tsunami. Based on the analysis, the shelters obtained can accommodate the population in tsunami-prone areas. The evacuation route can be determined by considering the distance, road width, road conditions, road class, and travel time to obtain the fastest route from settlement to the nearest shelter. The evacuation routes that can be used in Watulimo District are the existing roads. However, there is a need for road repairs in damaged/ potholed road conditions, road widening, adding new roads to facilitate the evacuation process of disaster victims to the shelter, and carrying out routine road maintenance on roads that will be used as evacuation routes, so that these roads are always in good condition.
Perkembangan Wilayah, Keselarasan Penggunaan Lahan Dengan Pola Ruang, Dan Arahan Rencana Pengembangan Wilayah Kabupaten Tangerang
Authors: Rismawati Iis , Sitorus Santun R.P , Darmawan Darmawan
Published: June 2021

Tangerang Regency has an economic structure dominated by the industrial sector. Population distribution, settlement location and industrial influenced land use patterns and regional development levels in Tangerang Regency. The objectives of this research are: to analyze the level of regional development and regional development inequality and factors that influence regional development; to analyze regional typology; to evaluate the consistency of land use with the Spatial Planning; and to formulate direction of the Tangerang Regency regional development plan. The method used are scalogram analysis, theil entrophy index analysis, cluster analysis, overlay and descriptive analysis. The results showed that the regional development level of the southern part of the region was higher than the northern part and the level of regional development inequality in the northern part of the region was higher than the southern part. Factors that influence the level of regional development are the percentage of settlement and industry areas, and the value of economic index, education index, and health index. Concerning typology of the area, in the northern part land use is dominated by agriculture, while in the southern region dominated by settlements and industries. The inconsistency of land use with spatial plan found mostly in the northern region. Thus, the first priority of regional development direction is to be located in the northern part that has a low level of regional development, high inequality value, high percentage of inconsistency of land use with spatial plan, and land use that is dominated by agriculture.
Analisis Zonasi Hijau di Jakarta
Authors: Setiowati Retno , Hasibuan Hayati Sari , Koestoer Raldi Hendro
Published: June 2021

Rapid development and increasing population causes the green open space in Jakarta is decreasing in size every year. Green open space is one of the keys to the sustainability of a city. The purpose of this study was to analyze the area of green space, green space distribution, and deviation between the green zone plan of the Regional Regulation of RDTR PZ and existing green space in Jakarta using Geographic Information Systems. Based on satellite imagery in 2018, the area of green space in Jakarta is 3,473.94 ha (5.31%). The highest green space area in 2018 is in the green belt zone (H4) of 1,557.88 ha and the lowest in the urban forest zone (H1) is 235.13 ha. The green zoning plan based on the Regional Regulation on RDTR and PZ is only 7,520.96 ha (11.51%) and is far from the mandate stipulated in Law Number 26 Year 2007 and the Jakarta 2030 RTRW of 30%. The highest area of green open space in the Regional Regulation of RDTR and PZ is in the green belt zone (H4) of 4,539.40 ha and the lowest in the urban forest zone (H1) is 17,58 ha. Based on the comparison of the area of green space in 2018 with the green plan RDTR and PZ it is known that there are 4 administrative city areas that experience a shortage of green space, namely South Jakarta, East Jakarta, West Jakarta and North Jakarta, while for Central Jakarta it has exceeded the green plan specified.
Pengarusutamaan Sustainable Development Goals (SDGS) Program Pengentasan Kemiskinan di Kota Pagar Alam
Authors: Rachmatullah Ricky , Endaryanto Teguh , Affandi M Irfan
Published: June 2021

Poverty is one of the indicators in judging the succeded sustainable development efforts. This study aims to analyze correlation between poverty alleviation budget programs by the Government and Local Government of Pagar Alam City with the percentage of poverty levels and determine poverty alleviation priority programs can be pursued by the Local Government of Pagar Alam City related to the achievement of SDGs mainstreaming target on 2030. The analytical method in this study uses the Pearson Correlation and Analytical Hierarchy Process (AHP). The results showed that the poverty allevation program budget had a signifiant corelation to the poverty percentage reduction in collaborative and synergistic budgeting through the APBD of Pagar Alam with APBN. Based on the assessment in the AHP model, the Social Welfare Services and Rehabilitation Program is first ranked or the first choice in the framework of poverty alleviation by SDGs mainstreaming.
Prioritas Penghuni Terkait Perawatan Rumah Susun Sederhana Sewa di Surabaya
Authors: Kusuma Edward Gondo , Anastasia Njo
Published: June 2021

Previous research focused on the conditions, awareness, and priorities of tenants for property maintenance in housing and middle-class flats, so that simple flats have not received special attention related to property maintenance issues. This study aims to determine the maintenance priority, the reasons given by tenants to maintain simple flat, the correlation between maintenance priorities and the reasons for maintain. The method used was a survey by distributing questionnaires. Property maintenance is divided into three such as structure, architecture and utility. The results show that each tenant has different priorities on property maintenance and their reasoning behind it. Disagreements occur in each of the tenants, where some of them are more concerned with maintenance and reasons for utility maintenance rather than structure and architecture maintenance. The more important the maintenance is, the stronger reason to do the maintenance. This research provides benefit to the management, namely the Surabaya City Governement, to develop procedures that can be proposed by tenants to obtain maintenance for damaged flat in accordance with priority needs of tenants. The managers can also develop maintenance strategies before and after damaged occur.
Pengaruh Internet Terhadap Intensi Migrasi Internasional Kaum Muda di Perdesaan (Studi Kasus di Desa Tambakasri)
Authors: Prayitno Gunawan , Nursaputra Zendy Nugraha , Subagiyo Aris , Wigayatri Mayang
Published: June 2021

Tambaksari Village is one of the villages located in Sumbermanjing Wetan District, the main activity of which is agriculture. However, data from Malang Regency in Figures for 2019 shows that 316 residents were recorded leaving the Sumbermanjing District to work as migrant workers. Migration of people outside the village can result in reduced resources for village development and agricultural land managers, most of whom are in rural areas. The aim of this study is to determine the impact of the Internet on young people 's intention to migrate abroad in terms of use. Based on the survey results, the entire Tambakasri Village area has been served by a mobile Internet network, as well as WiFi hotspots in several locations (Tambakasri Village Office and several coffee shops). Descriptive statistics and SEM-PLS were the data analysis method used. Based on the results of the analysis, it is known that the variable with the greatest total effect in the measurement of the INTENSE variable is the KONTEN variable + 0.001 (INFRAS and USE are negative). This means that the variable CONTEN is the variable that has the most dominant influence on the INTENSI variable in international migration, but can not be separated from INFRAS and USE. Based on the results of the test hypotheses, it is known that the Internet Influence variable consisting of indicators A, B and C has a significant effect on the International Youth Migration Intents variable in rural areas with an effect value based on the R-Squared value of 0.47 or 47 percent.
Investigating the Strength of the Indian Monsoons during Climate Extremes with Stable Isotope Records in Corals
Authors: Varkey Hannah , Mortlock Richard , Mchugh Cecilia , Mondal Dhiman
Published: June 2021

The Indian monsoon affects the lives of over a billion inhabitants living in southern Asia via the hy-drological cycle. Agriculture on land and freshwater discharge into the ocean. This discharge and nutri-ent cycling are tied with the monsoon cycles that di-rectly impact society and the economy. Previous studies have demonstrated a strong connection be-tween the strength of the Indian monsoon and the cooling of the North Atlantic during climate ex-tremes, such as during the last glacial period 20,000 years ago, and the Little Ice Age (~1300-1870 A.D.). In our study, we compare the relative strength of the monsoon during two different climate states: the Lit-tle Ice Age (LIA) and the modern (2015) with proxy measurements obtained in surface corals from Saint Martin’s Island, Southeast Bangladesh. We used the oxygen-isotope 18O/16O ratio (δ18Oc) of coralline aragonite (CaCO3) to reconstruct changes in the δ18O of seawater (δ18Ow) attributed to freshening from monsoon rains. During both climate states, corals recorded large variations in δ18Oc (up to 2 parts per thousand or ‰). We attribute these changes, in part, to local salinity changes which are reflected by variability in δ18Ow from local riverine discharge. While our records only represent 5-year snapshots and may not be representative of the av-erage climate state, this data does not support that the monsoon was substantially weaker during the LIA compared to the modern. In this study, the coral records indicate subtle patterns of isotopic compo-sition as a function of precipitation and temperature variability, serving as a preliminary for further study through longer records lasting a century. Beyond this, it would better our understanding of interac-tions between extremes in temperature and climate systems.
Particle Trajectories For Compton Scattering in One Space Dimension
Authors: Scanteianu Adriana , Wang Xiangyue
Published: June 2021

Using a relativistic extension of Bohmian Me-chanics known as Multi-Time Wave Function formula-tion, we examine a two-body, one-dimensional sys-tem consisting of one photon and one electron that interact only upon contact. We investigate the effects that various parameters in this theory including mo-mentum of the incoming photon and mass of the electron have on the dynamics of the two interact-ing bodies with the goal of understanding conser-vation of momentum and energy in the system. We show that the core principles of Compton scattering remain when we use this alternative formulation of quantum mechanics. Although a complete relativ-istic theory of Bohmian mechanics has yet to be de-veloped, our work aims to make the ideas in this the-ory more accessible to a wider audience.
Smartphone videoscopy: Recent progress and opportunities for biosensing
Authors: Wang Yan , Zhang Shengwei , Wei Qingshan
Published: June 2021

Smartphone is emerging as a portable analytical biosensing platform in many point-of-care (POC) applications such as disease diagnostics, environmental monitoring, and food toxin screening. With the recent advancement of imaging technologies on the smartphone, the manual control of acquisition settings (e.g., exposure time, frame rate, focusing distance, etc.) has already been expanded from the photo to the video capturing mode. In modern smartphone models, high frame rate (above 100 fps) can be achieved to bring in a new temporal dimension to the smartphone-supported POC tests by recording high-definition videos. This opens up a new analytical method defined as smartphone videoscopy. In this review, the recent development of smartphone videoscopy is summarized based on different POC applications. Representative examples of smartphone videoscopy systems and how these time-dependent measurements could open up new opportunities for POC diagnostics are discussed in detail. The advances demonstrated so far illustrate the promising future of smartphone videoscopy in biosensing, POC diagnostics, and time-resolved analysis in general.
Friction in the Creative City
Authors: De Beukelaer Christiaan
Published: June 2021

The Indonesian city of Bandung presents itself as an “emerging creative city.” This raises the question of how an “emerging” creative city can attain realisation: when and where is the creative city accomplished? The formalisation of the creative city creates friction – to borrow the term from Tsing. This friction manifests in two ways. First, through its ontological opacity (what is the creative city?), Mould contrasts the “Creative City” (the mainstream understanding of the term) with the lowercase “creative city” (the more grounded, subversive understanding of the term). Second, through political contestation (how and for whom is the creative city?) which Peck and Theodore question through the notion of “fast policy,” in dialogue with the notion of “slow policy.” However, rather than being a dead end, this article argues that “friction” can repoliticise the creative city by challenging the depoliticisation that occurred through its formalisation.
Contribution of collaborative skill toward construction drawing skill for developing vocational course
Authors: Setiawan Abdul Haris , Takaoka Ryo , Tamrin Agusti , Roemintoyo  , Murtiono Eko Supri , Trianingsih Lilis
Published: June 2021

This study aims to support developing research in designing a vocational lesson and learning model for civil engineering education study program by examining students’ collaborative skills toward construction drawing skills as a substantial skill in civil engineering. This study investigated student performance for proposing collaborative learning approaches to improve student skills as needed by industry. It is an ex-post-facto study using 130 samples from several vocational high schools in Indonesia with descriptive statistics and regression for the data analysis. The results show that the collaborative skill is in a fair category of 60.00 and the construction drawing skill is in a good category of 67.49 on a 100 scale. There is a significant and positive influence of collaborative skill (X) toward construction drawing skill (Y) with a linear regression model Ŷ = 31.443 + 1.952X. Furthermore, it presented a correlation coefficient of 0.644, a determination coefficient (R
2) of 0.415, and an adjusted R
2 of 0.410, where it can be concluded that the collaborative skill variable (X) as a predictor in the regression model includes the moderate category, which gives a 41% contribution in explaining the variants of the construction drawing skill (Y) as the dependent variable. It needs special attention to the specific behavioral details of the collaborative skill. The future work is needed to improve collaborative skills that emphasize prioritizing collaboration between peers and learning interdependence.
Miniaturized bandpass filter using coupled lines for wireless applications
Authors: Mohamadinia Abbas , Shama Farzin , Sattari Mohammad Amir
Published: June 2021

In this paper, a bandpass filter (BPF) has been designed using bent and coupled-line structure. The design process of the filter to achieve a BPF with good characteristics is completely explained. Therefore the LC equivalent circuit of The BPF is presented as the analytical description. The proposed filter can pass frequencies between 2.2 and 3.6 GHz with an insertion loss <0.4 dB, which is suitable for wireless applications. The fractional bandwidths (FBW) of the filter is about 48%. Some characteristics such as small size, low insertion loss, high return loss wide upper stopband bandwidth, and good suppression level in stopband are among the advantages of this study to be mentioned. Finally, the presented filter was fabricated, and the measured results have a proper agreement with the simulation results.
Infinitesimals via Cauchy sequences: Refining the classical equivalence
Authors: Bottazzi Emanuele , Katz Mikhail G.
Published: June 2021

A refinement of the classic equivalence relation among Cauchy sequences yields a useful infinitesimal-enriched number system. Such an approach can be seen as formalizing Cauchy’s sentiment that a null sequence “becomes” an infinitesimal. We signal a little-noticed construction of a system with infinitesimals in a 1910 publication by Giuseppe Peano, reversing his earlier endorsement of Cantor’s belittling of infinitesimals.
Vibration analysis of a sandwich cylindrical shell in hygrothermal environment
Authors: Zhang Chunwei , Jin Qiao , Song Yansheng , Wang Jingli , Sun Li , Liu Haicheng , Dun Limin , Tai He , Yuan Xiaodong , Xiao Hongmei , Zhu Limeng , Guo Songlin
Published: June 2021

The sandwich structures are three- or multilayered structures such that their mechanical properties are better than each single layer. In the current research, a three-layered cylindrical shell including a functionally graded porous core and two reinforced nanocomposite face sheets resting on the Pasternak foundation is used as model to provide a comprehensive understanding of vibrational behavior of such structures. The core is made of limestone, while the epoxy is utilized as the top and bottom layers’ matrix phase and also it is reinforced by the graphene nanoplatelets (GNPs). The pattern of the GNPs dispersion and the pores distribution play a crucial role at the continuous change of the layers’ properties. The sinusoidal shear deformation shells theory and the Hamilton’s principle are employed to derive the equations of motion for the mentioned cylindrical sandwich shell. Ultimately, the impacts of the model’s geometry, foundation moduli, mode number, and deviatory radius on the vibrational behavior are investigated and discussed. It is revealed that the natural frequency and rotation angle of the sandwich shell are directly related. Moreover, mid-radius to thickness ratio enhancement results in the natural frequency reduction. The results of this study can be helpful for the future investigations in such a broad context. Furthermore, for the pipe factories current study can be effective at their designing procedure.
Humility and its role for healing in the work of C.G. Jung and Kurt Schwitters
Authors: Milovanovic Jadranka
Published: June 2021

Humility of universal value. It pervades different layers of human existence. Examples abide in religion, in psychology, and art. Its presence offers rich sources of material and interesting parallels with Jung’s writings. Humility is unfortunately generally viewed as a weakness to the point of ridicule. In this view it is something to be avoided, hidden, rejected, or in some cases concealed by the opposite attitude such as false humility. In Jungian Psychology this weakness belongs to the shadow side of personality and is related to ego defenses. This is why Jung views humility as the acceptance of the shadow and considers it necessary for healing in the process of individuation. The immediate parallel is to be found in the words of St. Paul Cor. 12,9; “my power is manifest in weakness”; referring to the kind of weakness which means being completely supple, transparent, and abandoned to the power that goes beyond our conscious mind.
Pacifica Radio’sMusic from the Hearts of Spaceand the Ambient Sound of California’s New Age
Authors: Szabo Victor
Published: June 2021

Music from the Hearts of Space, a freeform music program that aired across Northern California on KPFA-FM Pacifica Radio from 1973, set forth an expansive transgeneric vision of contemplative atmospheric “space music” whose properties, in the following decades, would become more popularly codified as either “new age” or “ambient.” Histories of these latter genres typically separate out ambient’s avant-garde lineage and secular functionalism from new age’s therapeutic and spiritual concerns; but an examination of Hearts’s first decade on the air, leading up to its 1983 syndication via National Public Radio’s satellite network, reveals a sonic and cultural milieu that belies this eventual generic split. Through investigation of Hearts’s private archive and interviews with the program’s host Stephen Hill, as well as industry research, cultural-historical study, and style analysis, I situate the genesis of Hearts’s proto-ambient sound within the Bay Area’s new age movement of the 1970s and early 1980s. Informed by the metaphor of the global media environment established in systems theory and popularized by Marshall McLuhan and Stewart Brand, artists and media producers within this grassroots technoculture designed and spread “alternative” personal media for the development of holistic awareness. These media included slow, reverberant, hypnotic recorded music, as curated by Hill and his cohost Anna Turner under the guiding concept of “space music.” This early history and analysis of Hearts’s space music as an atmospheric medium for attuning the listening self to a worldwide media ecology deepens and complicates genealogies that isolate the formation of ambient music from that of new age, revealing a cross-pollination of highbrow and countercultural ideals that led many musicians associated with the new age movement to similar sonic conclusions to those of ambient music architect Brian Eno.
Clinical and biochemical signs of polycystic ovary syndrome in young women born preterm
Authors: Paalanne Marika , Vääräsmäki Marja , Mustaniemi Sanna , Tikanmäki Marjaana , Wehkalampi Karoliina , Matinolli Hanna-Maria , Eriksson Johan , Järvelin Marjo-Riitta , Morin-Papunen Laure , Kajantie Eero
Published: June 2021

Objective

It has been suggested that adverse early life exposures increase the risk of developing polycystic ovary syndrome (PCOS) in later life. We hypothesized that women born preterm would have more biochemical and clinical signs of PCOS than women born at term.

Design

The ESTER Preterm Birth Study participants were born in Northern Finland and identified from the Northern Finland Birth Cohort and the Finnish Medical Birth Register. Altogether, 74 women born very or moderately preterm (<34 gestational weeks, VMPT), 127 born late preterm (at 34–36 weeks, LPT), and 184 born full term (≥37 weeks, controls) were included in the analysis (mean age: 23.2 years).

Methods

We measured serum total testosterone and sex hormone-binding globulin (SHBG) and calculated the free androgen index (FAI). PCOS according to the clinical and biochemical signs was defined either as hirsutism and oligoamenorrhea (via questionnaire) or as oligoamenorrhea and elevated testosterone levels (>2.4 nmol/L).

Results

Women born VMPT/LPT exhibited 33.0% (8.7, 62.8)/16.4% (−2.0, 38.1) higher testosterone, 28.5% (5.3, 45.9)/24.1% (5.6, 38.9) lower SHBG levels, and 64.6% (19.4, 127.1)/42.5% (11.1, 82.9) higher FAI than controls after adjusting for age and recruitment cohort, maternal BMI, smoking, and pregnancy disorders, parental education, history of hypertension, diabetes, myocardial infarction or stroke, and subject’s birth weight s.d. Odds ratios for having PCOS were 1.67 (0.44, 6.23)/3.11 (1.26, 7.70).

Conclusions

Women born preterm have a more hyperandrogenic hormonal profile, and those born LPT are approximately three times more likely at risk to have PCOS compared to women born at term.
Preparation and characterization of bio-based activated carbon from fish scales
Authors: Ji Qingsong , Li Haichao , Zhang Jingjing
Published: June 2021

The object of this study was to prepare activated carbons containing nitrogenous functional groups by a chemical method from nitrogen-containing raw materials. Fish (Ctenopharyngodon idellus) scales were impregnated with phosphoric acid (H3PO4) and activated at varied temperatures. The adsorption ability, structural characteristics, surface chemistry, and morphology of the activated carbons were characterized by methylene blue and iodine values, nitrogen adsorption, the Boehm method, scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). The total alkaline groups content of the activated carbon produced from fish scales was 0.4330 mmol/g, the total acidic groups was 1.68 mmol/g, the Brunauer–Emmett–Teller (BET) surface area was 501 cm2/g, and the total pore volume was 0.284 cm3/g. The average pore diameter was 1.94 nm under an activation temperature of 550 °C, an activation time of 1 h, and an impregnation ratio of 2. As a result of this study, nitrogenous functional groups that contained acid-base amphoteric adsorbent were produced.
A new method to evaluate the hand-feel potential of furnishes for tissue paper products
Authors: Prinz Marcel , Zollner-Croll Helga , Bauer Wolfgang , Meltzer Frank P.
Published: June 2021

The human perception of softness is an important yet complex property of hygiene tissue paper products. Softness is a function of the combination of machine technology, chemical additives, and furnish composition. As a result, it is difficult to investigate the influence of single parameters. Because no completely satisfactory method for determining the softness of furnishes is available at the laboratory scale, the influence of different fibrous materials in combination with their treatment cannot be comprehensively investigated. To work toward this possibility, this publication describes the development of a method to obtain reliable results based on laboratory handsheets using a modified tissue softness analyzer (TSA). With the help of basic statistical methods, a procedure was developed that reproducibly distinguished the influence between softwood and hardwood. To demonstrate the potential of this method, it was tested on an industrial tissue machine and the influence of four different furnishes on the softness of the semi-finished product was determined.
Broader driver of disrespectful maternity care: power dynamics
Authors: Diorgu Faith C , George Awoala N
Published: June 2021

Understanding the dynamics under which women experiences birth and disrespectful care is important. It recognizes the relegation women experiences within a subjugated relationship between women and health care practitioners arising from power disparities. When power dynamics are acknowledged and everyone’s expertise respected, women have positive and healthy childbirth with respect to human’s fundamental right. This is the kind of care women want and need.
Decreasing the Use of Restraints on Children Admitted for Behavioral Health Conditions
Authors: Dalton Evan M. , Herndon Alison C. , Cundiff Allyson , Fuchs D. Catherine , Hart Sarah , Hughie Andrea , Kreth Heather L. , Morgan Kate , Ried Ashley , Williams Derek J. , Johnson David P.
Published: June 2021

OBJECTIVES

Pediatric behavioral health admissions to children’s hospitals for disposition planning are steadily increasing. These children may exhibit violent behaviors, which can escalate to application of physical limb restraints for safety. Using quality improvement methodology, we sought to decrease physical restraint use on children admitted to our children’s hospital for behavioral health conditions from a baseline mean of 2.6% of behavioral health patient days to <1%.

METHODS

We included all children ≥3 years of age admitted to our hospital medicine service with a primary behavioral health diagnosis from July 1, 2016, to February 1, 2020. A multidisciplinary team, formed in July 2018, tested interventions based on key drivers targeted toward our aim. The primary outcome measure was the percent of behavioral health patient days on which physical restraints were ordered. The balancing measure was the percent of patient days with a staff injury event. Statistical process control charts were used to view and analyze data.

RESULTS

Our cohort included 3962 consecutive behavioral health patient encounters, encompassing a total of 9758 patient days. A 2-year baseline revealed physical restraint orders placed on 2.6% of behavioral health patient days, which was decreased to 0.9% after interventions and has been sustained over 19 months without any change in staff injuries.

CONCLUSIONS

Team-based quality improvement methodology was associated with a sustained reduction in physical restraint use on children admitted for behavioral health conditions to our children’s hospital. These results indicate that physical restraint use can be safely reduced in children’s hospitals.
ДОСЛІДЖЕННЯ КІНЕТИКИ ТЕРМІЧНОГО РОЗКЛАДАННЯ РИСОВОГО ЛУШПИННЯ, ОЧИЩЕНОГО ВІД ЦЕЛЮЛОЗИ
Authors: Є. Скнар Юрій , В. Гриднєва Тетяна , О. Ляшенко Анна , В. Рябік Павло , В. Скнар Ірина , А. Гриднєв Єгор
Published: June 2021

Актуальним завданням сучасного матеріалознавства є підвищення характеристик матеріалів при зниженні енерговитрат і екологічного навантаження на навколишнє середовище при їх синтезі. Одним з матеріалів надзвичайно широкого спектру призначення є силіцій (IV) оксид. Вимоги до його експлуатаційних характеристик на сучасному рівні зводяться до отримання нанорозмірного аморфного силіцій (IV) оксиду високої чистоти. Екологізація виробництва силіцій (IV) оксиду може бути досягнута використанням в якості поновлюваної і дешевої сировини відходів рисового виробництва – рисового лушпиння. Технологія отримання силіцій (IV) оксиду з рисового лушпиння є менш енерговитратною в порівнянні з традиційною переробкою кварцу і рівень забруднюючого впливу на навколишнє середовище такої технології істотно нижче. Для отримання силіцій (IV) оксиду з рисового лушпиння з високим ступенем чистоти в даній роботі запропоновано проводити перед термообробкою рослинної сировини екстракційний витяг аморфної складової целюлози. Ця операція проводилась за температури 100 °C протягом 6 годин при перемішуванні пульпи в 15 %-му розчині сульфатної кислоти. Аналіз фазового складу силіцій (IV) оксиду, отриманого з рисового лушпиння після кислотної обробки, показав, що аморфна фаза SiO2 може бути одержана в діапазоні температур 600–650 °C На підставі результатів дослідження кінетики термодеструкції рисового лушпиння в неізотермічному режимі запропонована математична модель процесу, яка дозволяє визначати ступінь розкладання рисового лушпиння в залежності від температури його термообробки. Це необхідно для проектування обладнання з переробки рисового лушпиння в виробництві силіцій (IV) оксиду високої чистоти.
Fiestas trashumantes: liderazgos comunitarios y fiestas patronales afrocolombianas del pacífico en Bogotá
Authors: Rojas Juan Sebastián
Published: June 2021

En este artículo denomino “fiestas trashumantes” las fiestas patronales afrocolombianas del Pacífico que se celebran en Bogotá desde hace cerca de treinta años. Analizo, desde una aproximación etnográfica, las fiestas trashumantes de la Virgen de Atocha y San Pacho y argumento que estas prácticas culturales fortalecen los lazos, vividos e imaginados, con las tradiciones ancestrales de la región del Pacífico. A la vez, articulan procesos de organización comunitaria a nivel local y distrital, así como espacios de participación étnica y cultural para la comunidad afrocolombiana que reside en la capital. Las performances musicales y religiosas, desarrolladas al amparo de las políticas y escenarios multiculturales de la ciudad, ayudan a tejer sentido de comunidad, cumplen funciones de construcción de identidad y finalmente sirven como oferta estatal multicultural y espectáculo étnico.