bluuebunny/crossref_metadata_2025 huggingface dataset:
Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study
Authors: Tsiachris Dimitris , Papakonstantinou Panteleimon E. , Doundoulakis Ioannis , Tsioufis Panagiotis , Botis Michail , Dimitriadis Kyriakos , Leontsinis Ioannis , Kordalis Athanasios , Antoniou Christos-Konstantinos , Mantzouranis Emmanouil , Iliakis Panagiotis , Vlachakis Panayotis K. , Gatzoulis Konstantinos A. , Tsioufis Konstantinos
Published: October 2023

Background and Objectives: The proper use of oral anticoagulants is crucial in the management of non-valvular atrial fibrillation (AF) patients. Left atrial appendage closure (LAAC) may be considered for stroke prevention in patients with AF and contraindications for long-term anticoagulant treatment. We aimed to assess anticoagulation status and LAAC indications in patients with AF from the HECMOS (Hellenic Cardiorenal Morbidity Snapshot) survey. Materials and Methods: The HECMOS was a nationwide snapshot survey of cardiorenal morbidity in hospitalized cardiology patients. HECMOS used an electronic platform to collect demographic and clinically relevant information from all patients hospitalized on 3 March 2022 in 55 different cardiology departments. In this substudy, we included patients with known AF without mechanical prosthetic valves or moderate-to-severe mitral valve stenosis. Patients with prior stroke, previous major bleeding, poor adherence to anticoagulants, and end-stage renal disease were considered candidates for LAAC. Results: Two hundred fifty-six patients (mean age 76.6 ± 11.7, 148 males) were included in our analysis. Most of them (n = 159; 62%) suffered from persistent AF. The mean CHA2DS2-VASc score was 4.28 ± 1.7, while the mean HAS-BLED score was 1.47 ± 0.9. Three out of three patients with a a CHA2DS2-VASc score of 0 or 1 (female) were inappropriately anticoagulated. Sixteen out of eighteen patients with a CHA2DS2-VASc score 1 or 2 (if female) received anticoagulants. Thirty-one out of two hundred thirty-five patients with a CHA2DS2-VASc score > 1 or 2 (if female) were inappropriately not anticoagulated. Relative indications for LAAC were present in 68 patients with NVAF (63 had only one risk factor and 5 had two concurrent risk factors). In detail, 36 had a prior stroke, 17 patients had a history of major bleeding, 15 patients reported poor or no adherence to the anticoagulant therapy and 5 had an eGFR value < 15 mL/min/1.73 m2 for a total of 73 risk factors. Moreover, 33 had a HAS-BLED score ≥ 3. No LAAC treatment was recorded. Conclusions: Anticoagulation status was nearly optimal in a high-thromboembolic-risk population of cardiology patients who were mainly treated using NOACs. One out of four AF patients should be screened for LAAC.
Assessing the Level of Knowledge and Experience Regarding Cervical Cancer Prevention and Screening among Roma Women in Romania
Authors: Voidăzan Septimiu , Budianu Alexandra Mihaela , Francisc Rozsnyai Florin , Kovacs Zsolt , Uzun Cosmina Cristina , Apostol Bianca Elena , Bodea Reka
Published: October 2023

Background and Objectives: Romania ranks among the countries with a particularly high rate of mortality that can be prevented through prevention programs, screening, early detection, and prompt care. Cervical cancer (CC) is a major cause of these preventable deaths, affecting individuals from marginalized and rural regions, as well as the Roma population. The purpose of this article was to identify accurate and consistent information about the Roma population on the risk of CC, as well as the importance of understanding the causes of the disease and awareness of the available prevention methods. Materials and Methods: A cross-sectional study was conducted using a self-administered questionnaire applied only to Roma women in Romania. Results: We enrolled 759 patients in this study. These were divided into two groups: Group 1 comprised 289 (38.1%) women who had been tested for HPV infection, while Group 2 included 470 (61.9%) women who had never been tested for HPV infection. Characterization of women in Group 1: mostly aged between 25 and 54 years, with high school education, married, who started sexual activity under the age of 18 years, with only one sexual partner, and had over five pregnancies. Regarding contraceptive methods, 35.7% of women do not know or use any contraceptive method, and 32.2% use hormonal contraceptives. Two thirds of the women tested had heard of HPV, and 19.7% were vaccinated against HPV with at least 2–3 doses. A percentage of 8.7 had a diagnosis of CC, compared to those who were not tested (p-0.0001), whereas 63% of the tested women did not know much about CC, as opposed to 85.7% of the group of untested women. Conclusions: Cervical cancer (CC) continues to be a public health concern in Romania, particularly among vulnerable groups. Promoting campaigns to raise awareness for HPV vaccination and CC screening are necessary to reduce the associated mortality and morbidity.
Impact of the Membrane Structure of the Stationary Phase on Steric Exclusion Chromatography (SXC) of Lentiviral Vectors
Authors: Labisch Jennifer J. , Wiese G. Philip , Pflanz Karl , Linkhorst John
Published: October 2023

For steric exclusion chromatography (SXC), hydrophilic stationary phases are used to capture the target molecule in the presence of polyethylene glycol. The influence of the structure and pore size of the stationary phase on the process requirements are not yet well understood. To better understand the SXC process, membranes with different pore sizes that served as a stationary phase were compared for the purification of lentiviral vectors (LVs). A design of experiments (DoE) was performed to assess the combined impact of PEG concentration and membrane pore size on the purification performance. A visualization experiment showed that the LVs were captured on the first membrane layer for a pore size up to 2.2 µm, and for a pore size larger than 2.2 µm, LVs were also partly found on the second and third membrane layers. Moreover, we could observe that increasing membrane pore size requires a higher PEG concentration to achieve comparable LV recoveries. Using five membrane layers as a stationary phase was sufficient to achieve good performance, supporting the visualized capture results. In conclusion, we could show that each stationary phase has its optimal PEG buffer compositions for SXC, depending on the membrane structure and pore size.
Facile Synthesis and the Thermal Properties of Al/Si Composites Prepared via Fast Hot-Pressing Sintering
Authors: Jia Jianping , Hei Xiaoxuan , Li Zhou , Zhao Wei , Wang Yuqi , Zhuo Qing , Dong Hangyu , Li Yuanyuan , Liu Futian , Li Yingru
Published: October 2023

In this paper, a novel power sintering technique, named fast hot-pressing sintering (FHP), which is able to achieve an ultrahigh heating rate similar to the spark plasma sintering (SPS) technique, but at a much lower cost, was applied to prepare a series of Al/Si composites with different Si volume ratios (12 vol.% to 70 vol.%) to meet the requirements of advanced packaging materials for electronic devices. In contrast to SPS, the FHP oven possesses a safe and budget-friendly current power supply, rather than a complex and expensive pulse power supply, for its heating power. The optimized sintering parameters (temperature, pressure and holding time) of FHP for preparing Al/Si composites were investigated and determined as 470 °C, 300 MPa and 5 min, respectively. In order to characterize the potential of Al/Si composites as packaging materials, thermal conductivities and coefficients of thermal expansion were studied. The thermal conductivity of the Al-40Si composite sintered by the FHP method is higher than that of the conventional SPS method (139 to 107 W m−1 K−1). With the increase in Si, the thermal conductivities and coefficients of thermal expansion on both decreases. Furthermore, the thermal conductivities obey the Agari model, whereas the coefficient of thermal expansion and Si volume ratios obey additivity. The numeric modeling would help develop required packaging materials based on the thermal performances of the substrate materials, like Si or GaAs semiconductor devices.
Effect of Laser Surface Texturing on Schmid Factor and Plastic Deformation Mechanisms on AISI 301LN Steel
Authors: Rezayat Mohammad , Roa Joan Josep , Mateo Antonio
Published: October 2023

In this comprehensive study, the multifaceted impact of laser surface texturing (LST) on AISI 301LN stainless steel is explored. Changes in the microstructure, mechanical properties, and grain characteristics are examined. The dynamic relationship between Schmid factor evolution and plastic deformation in this stainless steel alloy is unveiled through the analysis of grain statistics and individual grain scrutiny. It is revealed that LST initiates the formation of strain-induced α’-martensite, grain refinement, and substantial hardness enhancements. Notably, an α’-martensite crystalline size of 2.05 Å is induced by LST. Furthermore, a 12% increase in tensile strength is observed after LST along with an 11% boost in yield strength. However, reductions of 19% in elongation to fracture and 12% in the area reduction are experienced.
Machine Learning in Enhancing Corrosion Resistance of Magnesium Alloys: A Comprehensive Review
Authors: Guo Yanbing , Sun Mingze , Zhang Wang , Wang Lvyuan
Published: October 2023

While magnesium alloys have garnered attention for their lightweight properties across diverse applications, their susceptibility to corrosion presents a formidable challenge. Recent years have witnessed the emergence of machine learning (ML) as a formidable tool for predicting and augmenting material properties, notably corrosion resistance. This comprehensive review investigates the latest advancements and hurdles in utilizing ML techniques to investigate the corrosion behavior of magnesium alloys. This article delves into a spectrum of ML algorithms, encompassing artificial neural networks, support vector machines, and random forests, elucidating their roles in predicting corrosion rates, morphologies, and other corrosion-related characteristics in magnesium alloys. Furthermore, it underscores the pivotal challenges and opportunities within this field, such as data quality, model interpretability, and model transferability. Finally, it examines the potential of ML methods in the conception and enhancement of magnesium alloys endowed with superior corrosion resistance. This review aspires to offer valuable insights into harnessing ML’s potential for optimizing magnesium alloy designs with heightened corrosion resistance, a facet of paramount importance across diverse industries, including the automotive, aerospace, and biomedical sectors. By addressing the challenges inherent in using ML to forecast corrosion rates, including data limitations and the intricacies of corrosion mechanisms, ML stands poised to emerge as a potent instrument for advancing the development of corrosion-resistant materials.
Genesis of the Yi’nan Tongjing Gold–Copper Skarn Deposit, Luxi District, North China Craton: Evidence from Fluid Inclusions and H–O Isotopes
Authors: Cai Wenyan , Liu Xiao , Zhang Zhaolu , Gao Jilei , Lei Ming , Cui Qingyi , Ma Ming , Li Yadong , Song Yingxin
Published: October 2023

The Luxi district presents an exceptional research area for the investigation of the significant role played by magma exsolution fluids in the mineralization process of Au–Cu deposits. A particularly noteworthy occurrence within this region is the Yi’nan Tongjing Au–Cu skarn deposit, situated in the central-southern part of the Luxi district. This deposit primarily occurs in the contact zone between the early Cretaceous Tongjing complex and the Proterozoic to Cambrian sequences. The ore formation process observed in this deposit can be categorized into three distinct stages: (I) thermal metamorphism, (II) prograde alteration, and (III) retrograde alteration. The retrograde alteration stage is further divided into four sub-stages: late skarn (III-1), oxide (III-2), sulfide (III-3), and late quartz-calcite (III-4). It is primarily during the III-3 sub-stage that gold mineralization occurs. Petrographic analysis has identified three types of fluid inclusions (FIs) within garnet, quartz, and calcite grains. These include liquid-rich two-phase aqueous FIs, vapor-rich two-phase aqueous FIs, and halite-bearing multi-phase FIs. The homogenization temperatures of fluid inclusions from stages II, III-3, and III-4 range between 430–457 °C, 341–406 °C, and 166–215 °C (first to third quartiles), respectively. The garnet samples from stage II exhibit hydrogen and oxygen isotope compositions (δ18OH2O = 6.8‰ and δD = −73‰) that are indicative of a typical magma source. However, the hydrogen and oxygen isotopes of sub-stages III-1, III-2, and III-3 (δ18OH2O = 7.32‰ to 9.74‰; δD = −107‰ to −81.9‰) fall below the magma water box while the hydrogen and oxygen isotope values of III-4 (δ18OH2O = −5.3‰ to −0.9‰ and δD = −103.8‰ to −67‰) tend to move towards the meteoric water line. Furthermore, the ore-forming fluid displays characteristics of a mixture between the crustal and mantle fluids. The Tongjing complex occurred along a weakened fault zone, initiating a process of thermal metamorphism upon contact with the wall rock. This thermal metamorphism resulted in the formation of diverse assemblages, including hornfels, reaction skarns, and skarnoids. Subsequently, the upward movement of ore-forming fluids triggered exsolution which led to the establishment of a high-temperature, medium-salinity NaCl–H2O system with a single phase at depths ranging from 1–3 km. This marked the formation of the prograde alteration stage. Afterward, the ore-forming fluid underwent water–rock interactions and the admixture of meteoric water at a depth of 1–2 km. These processes facilitated phase separation, commonly referred to as boiling, resulting in the transformation of the ore-forming fluid into higher salinity fluids and lower-density gases. This evolutionary transition ultimately induced the precipitation and liberation of gold and copper from the fluid.
Experimental and Modelling Study of Pt, Pd, and 2E+Au Flotation Kinetics for Platreef Ore by Exploring the Influence of Reagent Dosage Variations
Authors: Doubra Parisa , Carelse Candice , Chetty Deshenthree , Manuel Marian
Published: October 2023

This study investigates the flotation kinetics of individual platinum-group elements (PGEs) and gold, namely Pt, Pd, and 2E+Au (i.e., Pt+Pd+Au), in the context of Platreef ore flotation. Experimental tests were conducted on a Platreef ore feed using various dosages of depressants, frothers, and collectors under controlled agitation and pH conditions. The recoveries of the individual PGEs were analysed using six kinetic models, with the modified Kelsall model identified as the most suitable for accurately describing the flotation kinetics and predicting elemental recovery. Notably, the model incorporates two rate constants (kfast and kslow) to account for the distinct flotation behaviours of the PGEs. The results indicate that Pt has the fastest floatability, followed by Pd and 2E+Au. The modified Kelsall model demonstrates high effectiveness in predicting the recovery of these PGEs. Three empirical correlations for Pt, Pd, and 2E+Au recoveries based on the modified Kelsall model are proposed, enhancing the understanding and optimisation of PGE recovery in Platreef ore flotation.
Characteristics and Controlling Factors of Particle Crushing in Volcaniclastic Sediments under Compaction: The Quaternary Pyroclastic Deposits of Hongtu Hill, Changbaishan Area, Northeastern China
Authors: Bai Jiawei , Tang Huafeng , Hu Jia , Yang Liying , Guo Tianchan , Zhang Zhiqiang
Published: October 2023

Recently, many scholars have conducted experimental mechanical compaction studies on sandstones, carbonates, and mudstones to visually study the mechanical compaction process and reservoir evolution of sedimentary rocks. However, experimental mechanical compaction studies on the evolution of the compaction process of pyroclastic rocks have been ignored. Volcaniclastic rock reservoirs are widely distributed across the world and strongly influenced by the crushing of pyroclastic particles. In this study, we analyzed the characteristics and controlling factors of the crushing of pyroclastic particles during compaction diagenesis from a microscopic perspective through experimental mechanical compaction. These results can provide quantitative compaction background parameters for the quantitative study of pyroclastic rock reservoir evolution. We took pyroclastic samples from Hongtu Hill in the Changbaishan area as an example, and experimental mechanical compaction experiments were conducted. Furthermore, image surface porosity and particle analysis statistical methods were used, and the variations in the effective porosity and image surface porosity under different axial stresses were studied. The results showed that, after compaction, the effective porosity did not exhibit a decreasing trend with increasing axial stress but rather a normal distribution trend that initially increased and then decreased. In the compaction experiment, the pyroclastic particle crushing process was segmented with increasing axial stress, and there was an obvious compaction band in the initial stage of the compaction, called the particle rearrangement stage (10–30 MPa). Furthermore, there were relatively non-successive compaction localization areas in the later stage of compaction, called the particle crushing stage (50–70 MPa), which was represented by vitreous basalt particles surrounded by porphyritic basalt particles. During experimental mechanical compaction, the smaller the compactness, the smaller the solidity, and the larger the slenderness of the particles, the more likely the particles were to break during compaction. Particles containing intragranular pores and vitreous basalt particles were easily crushed.
Cholesterol Levels, Hormone Replacement Therapy, and Incident Dementia among Older Adult Women
Authors: Chiu Huei-Ying , Chang Hsin-Te , Chan Po-Chi , Chiu Pai-Yi
Published: October 2023

Previous studies revealed that hormone replacement therapy (HRT) probably has a protective effect for preventing dementia in post-menopausal women. However, the results were still controversial. The association between cholesterol levels and incident dementia in older women is not fully understood either. We conducted a retrospective analysis on a cohort of non-demented women aged older than 50 years, which was registered in the History-based Artificial Intelligence Clinical Dementia Diagnostic System database from September 2015 to August 2021. We followed this cohort longitudinally to examine the rates of conversion to dementia. Using a Cox regression model, we investigated the impact of the quartile of total cholesterol (TC) levels on incident dementia, adjusting for age, sex, education, neuropsychiatric symptoms, neuropsychological assessments, HRT, as well as various vascular risk factors and medications. We examined a cohort of 787 participants, comprising 539 (68.5%) individuals who did not develop dementia (non-converters). Among these non-converters, 68 individuals (12.6%) were treated with HRT. By contrast, there were 248 (31.5%) who did develop dementia (converters). Among the converters, 28 individuals (11.3%) were treated with HRT. The average follow-up durations were 2.9 ± 1.5 and 3.3 ± 1.6 years for non-converters and converters, respectively. Compared to the lowest quartile of TC levels (<153), the hazard ratios (HR) for converting to dementia were 0.61, 0.58, and 0.58 for the second (153–176), third (177–201), and highest (>201) quartiles, respectively (all p < 0.05). However, the low-density lipoprotein cholesterol (LDL-C) level and HRT did not alter the rate of conversion to dementia. In conclusion, the lowest quartile of TC increased incident dementia in post-menopausal women without dementia; however, HRT did not contribute to conversion to dementia. Some studies suggest that post-menopausal women who have reduced estrogen levels might have an increased risk of Alzheimer’s disease if they also have high cholesterol. Nonetheless, the evidence is inconclusive, as not all studies support this finding. The “Lower LDL-C is better” strategy for preventing cardiac vascular disease should be re-examined for the possible serial adverse effects of new onset dementia due to very low cholesterol levels.
Spatial Distribution and Contamination Level Assessment of Marine Sediment of the Safi Bay (Moroccan Atlantic Coast)
Authors: Minoubi Abdenaim , Mejjad Nezha , El Khalidi Khalid , Bouchkara Mohammed , Fadili Ahmed , Chaibi Mohamed , Zourarah Bendahhou
Published: October 2023

This study assesses the spatial distribution and contamination level of heavy metals in Safi Bay surface sediments. In this order, 28 surface sediment samples were retrieved from the study area and analyzed using the x-fluorescence method. To assess the contamination of the examined sediment, we used geo-ecological indices such as contamination factor (CF), degree of contamination (DC), geo accumulation index, and pollution load index (PLI). The results show that only Pb and Cd present moderate and considerable contamination in some sampling sites, while other elements (Cr, Cu, Zn, and Ni) indicate no contamination and low contamination by these elements. The inhomogeneous distribution of metal concentrations along the bay suggests different heavy metal sources. Given the ecological and socioeconomic importance of the study area, there is a need for a further analysis of both sediments and biological samples for a better understanding of the contamination levels and origin of metals, in addition to the sustainability of Safi Bay.
Septic Obturation of a Knee Endoprosthesis Caused by Aspergillus clavatus
Authors: Kuthan Robert , Zaremba-Wróblewski Gabriel Lawrence , Ott Flynn , Soltaninia Dorsa
Published: October 2023

Aspergillus clavatus is a rare opportunistic fungal pathogen that can be isolated from various environmental sources, including soil and animal feces. Although infrequent, infections caused by A. clavatus can be severe in immunocompromised patients. Here, we present a case of a prosthetic joint infection (PJI) in a 74-year-old female patient caused by A. clavatus. The patient presented with left knee pain, and septic loosening of the left knee endoprosthesis was diagnosed. She underwent surgical revision with the implantation of an antibiotic spacer and microbiologic testing. The results came back positive for both Staphylococcus lugdunensis and A. clavatus (which is found in only a fraction of a percent of PJIs). She was treated with oral antimicrobials for 3 months postoperatively. This case report vividly illustrates a clinical scenario that underscores the significance of rigorous microbiologic testing procedures, accurate pathogen identification, unwavering vigilance in testing protocols, and a cautious approach that avoids succumbing to the seductive simplicity of Occam’s razor.
Towards Effective Antiviral Oral Therapy: Development of a Novel Self-Double Emulsifying Drug Delivery System for Improved Zanamivir Intestinal Permeability
Authors: Ifrah Sapir , Dahan Arik , Debotton Nir
Published: October 2023

Self-double emulsifying drug delivery systems have the potential to enhance the intestinal permeability of drugs classified under the Biopharmaceutics Classification System (BCS) class III. One such example is the antiviral agent zanamivir, exhibiting suboptimal oral absorption (with a bioavailability range of 1–5%). To address this challenge, we have developed an innovative oral formulation for zanamivir: a self-double nanoemulsifying Winsor delivery system (SDNE-WDS) consisting of the microemulsion, which subsequently yields final double nanoemulsion (W1/O/W2) upon interaction with water. Two distinct formulations were prepared: SDNE-WDS1, classified as a W/O microemulsion, and SDNE-WDS2, discovered to be a bicontinuous microemulsion. The inner microemulsions displayed a consistent radius of gyration, with an average size of 35.1 ± 2.1 nm. Following self-emulsification, the resultant zanamivir-loaded nanoemulsion droplets for zSDNE-WDS1 and zSDNE-WDS2 measured 542.1 ± 36.1 and 174.4 ± 3.4 nm, respectively. Both types of emulsions demonstrated the ability to enhance the transport of zanamivir across a parallel artificial membrane. Additionally, in situ rat intestinal perfusion studies involving drug-loaded SDNE-WDSs revealed a significantly increased permeability of zanamivir through the small intestinal wall. Notably, both SDNE-WDS formulations exhibited effective permeability (Peff) values that were 3.5–5.5-fold higher than those of the low/high permeability boundary marker metoprolol. This research emphasizes the success of SDNE-WDSs in overcoming intestinal permeability barriers and enabling the effective oral administration of zanamivir. These findings hold promise for advancing the development of efficacious oral administration of BCS class III drugs.
Analysis of Coaxiality Error Induced by the Cube Corner Retro-Reflector Geometrical and Assembly Errors of an Acquisition, Pointing, and Tracking System
Authors: Li Daquan , Mao Zhaoyong , Sun Lijuan , Zhang Haifeng , Zhang Furui
Published: October 2023

Satellite laser communication is a promising technology for the next-generation communication system. Its communication performance is subject to the APT beam-pointing accuracy. One of the most important problems is reducing the coaxiality error before the APT starts working. However, the coaxiality error is difficult to correct effectively owing to the lack of empirical guidance based on qualitative analysis. We study the inducement that will generate coaxiality errors. The mathematical model of the influence of the CCR dihedral angle error and planeness error on the spot centroid measurement are built, and an analysis is performed. The model of the beam-pointing error induced by the APT element’s assembly error is built, and the pointing error change rule is explored. Furthermore, the coaxiality performance simulation is performed in the presence of a CCR geometrical error while considering the assembly error. The results show that the coaxiality error has a nonlinear characteristic. The CCR planeness error has a greater influence on coaxiality deviation than that of dihedral angle error under certain conditions. This research is relevant to the design and test work of the APT system.
Alleviation of Cadmium Toxicity in Thai Rice Cultivar (PSL2) Using Biofertilizer Containing Indigenous Cadmium-Resistant Microbial Consortia
Authors: Seang-On Ladda , Meeinkuirt Weeradej , Koedrith Preeyaporn
Published: October 2023

Biofertilizer as an amendment has growing awareness. Little attention has been paid to bioremediation potential of indigenous heavy-metal-resistant microbes, especially when isolated from long-term polluted soil, as a bioinoculant in biofertilizers. Biofertilizers are a type of versatile nutrient provider and soil conditioner that is cost-competitive and highly efficient with nondisruptive detoxifying capability. Herein, we investigated the effect of biofertilizers containing indigenous cadmium (Cd)-resistant microbial consortia on rice growth and physiological response. The Thai rice cultivar PSL2 (Oryza sativa L.) was grown in Cd-enriched soils amended with 3% biofertilizer. The composition of the biofertilizers’ bacterial community at different taxonomic levels was explored using 16S rRNA gene Illumina MiSeq sequencing. Upon Cd stress, the test biofertilizer had maximum mitigating effects as shown by modulating photosynthetic pigment, MDA and proline content and enzymatic antioxidants, thereby allowing increased shoot and root biomass (46% and 53%, respectively) and reduced grain Cd content, as compared to the control. These phenomena might be attributed to increased soil pH and organic matter, as well as enriched beneficial detoxifiers, i.e., Bacteroidetes, Firmicutes and Proteobacteria, in the biofertilizers. The test biofertilizer was effective in alleviating Cd stress by improving soil biophysicochemical traits to limit Cd bioavailability, along with adjusting physiological traits such as antioxidative defense. This study first demonstrated that incorporating biofertilizer derived from indigenous Cd-resistant microbes could restrict Cd contents and consequently enhance plant growth and tolerance in polluted soil.
Fabrication of a Fish-Bone-Inspired Inorganic–Organic Composite Membrane
Authors: Jiao YuYang , Okada Masahiro , Nutan Bhingaradiya , Nagaoka Noriyuki , Bikharudin Ahmad , Musa Randa , Matsumoto Takuya
Published: October 2023

Biological materials have properties like great strength and flexibility that are not present in synthetic materials. Using the ribs of crucian carp as a reference, we investigated the mechanisms behind the high mechanical properties of this rib bone, and found highly oriented layers of calcium phosphate (CaP) and collagen fibers. To fabricate a fish-rib-bone-mimicking membrane with similar structure and mechanical properties, this study involves (1) the rapid synthesis of plate-like CaP crystals, (2) the layering of CaP–gelatin hydrogels by gradual drying, and (3) controlling the shape of composite membranes using porous gypsum molds. Finally, as a result of optimizing the compositional ratio of CaP filler and gelatin hydrogel, a CaP filler content of 40% provided the optimal mechanical properties of toughness and stiffness similar to fish bone. Due to the rigidity, flexibility, and ease of shape control of the composite membrane materials, this membrane could be applied as a guided bone regeneration (GBR) membrane.
Synthesis, Characterization, and Environmental Applications of Novel Per-Fluorinated Organic Polymers with Azo- and Azomethine-Based Linkers via Nucleophilic Aromatic Substitution
Authors: Altarawneh Suha S. , El-Kaderi Hani M. , Richard Alexander J. , Alakayleh Osama M. , Aljaafreh Ibtesam Y. , Almatarneh Mansour H. , Ababneh Taher S. , Al-Momani Lo’ay A. , Aldalabeeh Rawan H.
Published: October 2023

This study reports on the synthesis and characterization of novel perfluorinated organic polymers with azo- and azomethine-based linkers using nucleophilic aromatic substitution. The polymers were synthesized via the incorporation of decafluorobiphenyl and hexafluorobenzene linkers with diphenols in the basic medium. The variation in the linkers allowed the synthesis of polymers with different fluorine and nitrogen contents. The rich fluorine polymers were slightly soluble in THF and have shown molecular weights ranging from 4886 to 11,948 g/mol. All polymers exhibit thermal stability in the range of 350–500 °C, which can be attributed to their structural geometry, elemental contents, branching, and cross-linking. For instance, the cross-linked polymers with high nitrogen content, DAB-Z-1h and DAB-Z-1O, are more stable than azomethine-based polymers. The cross-linking was characterized by porosity measurements. The azo-based polymer exhibited the highest surface area of 770 m2/g with a pore volume of 0.35 cm3/g, while the open-chain azomethine-based polymer revealed the lowest surface area of 285 m2/g with a pore volume of 0.0872 cm3/g. Porous structures with varied hydrophobicities were investigated as adsorbents for separating water-benzene and water-phenol mixtures and selectively binding methane/carbon dioxide gases from the air. The most hydrophobic polymers containing the decafluorbiphenyl linker were suitable for benzene separation, while the best methane uptake values were 6.14 and 3.46 mg/g for DAB-Z-1O and DAB-A-1O, respectively. On the other hand, DAB-Z-1h, with the highest surface area and being rich in nitrogen sites, has recorded the highest CO2 uptake at 298 K (17.25 mg/g).
Rapid Impregnating Resins for Fiber-Reinforced Composites Used in the Automobile Industry
Authors: Li Mei-Xian , Mo Hui-Lin , Lee Sung-Kwon , Ren Yu , Zhang Wei , Choi Sung-Woong
Published: October 2023

As environmental regulations become stricter, weight- and cost-effective fiber-reinforced polymer composites are being considered as alternative materials in the automobile industry. Rapidly impregnating resin into the reinforcing fibers is critical during liquid composite molding, and the optimization of resin impregnation is related to the cycle time and quality of the products. In this review, various resins capable of rapid impregnation, including thermoset and thermoplastic resins, are discussed for manufacturing fiber-reinforced composites used in the automobile industry, along with their advantages and disadvantages. Finally, vital factors and perspectives for developing rapidly impregnated resin-based fiber-reinforced composites for automobile applications are discussed.
The Beneficial Effect of Selenium-Enriched Broccoli on the Quality Characteristics of Bread
Authors: Martirosyan Vladimir V. , Kostyuchenko Marina N. , Kryachko Tatyana I. , Malkina Valentina D. , Zhirkova Elena V. , Golubkina Nadezhda A.
Published: October 2023

Broccoli is one of the most valuable representatives of the Brassicaceae family, characterized by high levels of glucosinolates and fiber, antioxidant status and tolerance to high selenium (Se) concentrations. To evaluate the efficiency of Se-enriched broccoli utilization in bread production, 4% of dry broccoli powder was added to dough using non-fortified and Se-biofortified broccoli florets. The resulting functional products were characterized by enhanced porosity, crump acidity and a specific volume exceeding those of the control bread by 109–110%, 114–121% and 107–112%, respectively, with the lower levels typical to bread with broccoli non-fortified with Se. By supplying broccoli powder to bread, the dietary fiber content of the product was enhanced by 2.1 times. Selenium-enriched broccoli powder supply improved the ascorbic acid and total phenolic content in bread by 37.5 and 2.03 times compared with the control. The effect was less pronounced in case of non-fortified broccoli supplementation due to the beneficial effect of Se on broccoli florets’ antioxidant status. Selenium-enriched broccoli supply significantly decreased the intensity of bread crumb hardening during storage. High Se-biofortification level (5.6) and insignificant Se losses during bread baking (less than 4%) confirm high prospects of Se-enriched broccoli utilization in the production of new functional bread with elevated levels of antioxidants, Se and dietary fiber.
Enhanced Performance of Micro Deep Drawing through the Application of TiO2 Nanolubricant and Graphene Lubricants on SUS 301 Stainless Steel Foil
Authors: Pan Di , Zhang Guangqing , Jia Fanghui , Lu Yao , Wang Jun , Li Zhou , Li Lianjie , Yang Ming , Jiang Zhengyi
Published: October 2023

In recent years, the quest for effective lubrication in micro deep drawing (MDD) has seen promising advancements. In this study, the influence of TiO2 nanolubricants and graphene lubricants on the performance of 301 stainless steel foil in MDD is examined. The MDD undergoes an extensive evaluation of various lubrication conditions, including dry, TiO2 nanolubricant, graphene lubricant at concentrations of 2.5 mg/mL, 5.0 mg/mL, and 10.0 mg/mL, as well as combined applications of TiO2 and graphene lubricants. Utilising a 5.0 mg/mL graphene lubricant together with TiO2 nanolubricants led to a significant reduction in drawing force, highlighting the synergistic efficacy of this combined lubricant. A pronounced enhancement in the consistency of the produced microcups was also attained. These results emphasise the promise of TiO2 nanolubricant and graphene lubricants in optimising the MDD process.
Analysis of Controllability in Cyber–Physical Power Systems under a Novel Load-Capacity Model
Authors: Ge Yaodong , Li Yan , Xu Tianqi , He Zhaolei , Zhu Quancong
Published: October 2023

In cyber–physical power systems (CPPSs), system collapse can occur as a result of a failure in a particular component. In this paper, an approach is presented to build the load-capacity model of CPPSs using the concept of electrical betweenness and information entropy, which takes into account real-time node loads and the allocation of power and information flows within CPPSs. By introducing an innovative load redistribution strategy and comparing it with conventional load distribution strategies, the superior effectiveness of the proposed strategy in minimizing system failures and averting system collapses has been demonstrated. The controllability of the system after cascading failures under different coupling strategies and capacity parameters is investigated through the analysis of different information network topologies and network parameters. It was observed that CPPSs constructed using small-world networks, which couple high-degree nodes from the information network to high-betweenness nodes from the power grid, exhibit improved resilience. Furthermore, increasing the capacity parameter of the power network yields more favorable results compared to increasing the capacity parameter of the information network. In addition, our research results are validated using the IEEE 39-node system and the Chinese 132-node system.
Beads and Ceremony: The Collision of Pan-American, European, African, and Asian Bead Networks in the Sixteenth-Century Spanish Empire
Authors: Beck Lauren
Published: October 2023

A powerful bead network that wove together a transcontinental tapestry of cultures predated the Spanish invasion of the Americas. Beads created in the northeastern Atlantic world found themselves in Aztec and Incan territories, as did beads made from rocks found in the Pacific Northwest, all of which had been borne along trade networks that have existed for ages. Sixteenth-century illustrations found in the Mexican codices demonstrate the traditional manufacture of beads, which were used for a range of quotidian and ceremonial purposes. Since medieval times, Spaniards employed beads, called rescate, as currency for inequitable trade, whether for slaves or precious metals. The Spanish invasion introduced beads manufactured in other parts of the world to the Americas to form part of the ceremonial and spiritually endowed objects and ceremonies, and vice versa, American beads made their way into Spanish clothing and religious objects such as the rosary. A significant infusion of new beads from Spain rushed into the American bead network in the sixteenth century, some of which had international origins from places such as Venice, India, and West Africa. As material objects, beads negotiated intercultural relationships in powerful ways throughout the Spanish empire: beads were involved in treaties, territorial agreements, prayer, spiritual relations, wayfinding, and most importantly, ceremony. This article maps out the collision of bead networks within the sixteenth-century Spanish empire so as to flesh out the similar and innovative uses of beads, whether among Native American, Afro-descendant, or European communities, and their connection to spiritual and ceremonial practices.
Surimi Production from Tropical Mackerel: A Simple Washing Strategy for Better Utilization of Dark-Fleshed Fish Resources
Authors: Panpipat Worawan , Thongkam Porntip , Boonmalee Suppanyoo , Çavdar Hasene Keskin , Chaijan Manat
Published: October 2023

Mackerel (Auxis thazard), a tropical dark-fleshed fish, is currently a viable resource for the manufacture of surimi, but the optimal washing procedure for more efficient use of this particular species is required right away. Washing is the most critical stage in surimi production to ensure optimal gelation with odorless and colorless surimi. The goal of this study was to set a simple washing medium to the test for making mackerel surimi. Washing was performed three times with different media. T1 was washed with three cycles of cold carbonated water (CW). T2, T3, and T4 were washed once with cold CW containing 0.3%, 0.6%, or 0.9% NaCl, followed by two cycles of cold water. T5, T6, and T7 were produced for three cycles with CW containing 0.3%, 0.6%, or 0.9% NaCl. For comparison, unwashed mince (U) and conventional surimi washed three times in cold tap water (C) were employed. The maximum yield (62.27%) was obtained by washing with T1. When varying quantities of NaCl were mixed into the first washing medium (T2–T4), the yield decreased with increasing NaCl content (27.24–54.77%). When washing with NaCl for three cycles (T5–T7), the yield was greatly decreased (16.69–35.23%). Conventional surimi washing (C) produced a yield of roughly 40%, which was comparable to T3. Based on the results, treatments that produced lower yields than C were eliminated in order to maximize the use of fish resources and for commercial reasons. The maximum NaCl content in CW can be set at 0.6% only during the first washing cycle (T3). Because of the onset of optimal unfolding as reported by specific biochemical characteristics such as Ca2+-ATPase activity (0.2 μmol inorganic phosphate/mg protein/min), reactive sulfhydryl group (3.61 mol/108 g protein), and hydrophobicity (64.02 µg of bromophenol blue bound), T3 washing resulted in surimi with the greatest gel strength (965 g.mm) and water holding capacity (~65%), with fine network structure visualized by scanning electron microscope. It also efficiently removed lipid (~80% reduction), myoglobin (~65% reduction), non-heme iron (~94% reduction), and trichloroacetic acid-soluble peptide (~52% reduction) contents, which improves whiteness (~45% improvement), reduces lipid oxidation (TBARS value < 0.5 mg malondialdehyde equivalent/kg), and decreases the intensity of the gel’s fishy odor (~30% reduction). As a result, washing mackerel surimi (A. thazard) with CW containing 0.6% (w/v) NaCl in the first cycle, followed by two cycles of cold water washing (T3), can be a simple method for increasing gel-forming capability and oxidative stability. The mackerel surimi produced using this washing approach has a higher quality than that produced with regular washing. This straightforward method will enable the sustainable use of dark-fleshed fish for the production of surimi.
SID-TGAN: A Transformer-Based Generative Adversarial Network for Sonar Image Despeckling
Authors: Zhou Xin , Tian Kun , Zhou Zihan , Ning Bo , Wang Yanhao
Published: October 2023

Sonar images are inherently affected by speckle noise, which degrades image quality and hinders image exploitation. Despeckling is an important pre-processing task that aims to remove such noise so as to improve the accuracy of analysis tasks on sonar images. In this paper, we propose a novel transformer-based generative adversarial network named SID-TGAN for sonar image despeckling. In the SID-TGAN framework, transformer and convolutional blocks are used to extract global and local features, which are further integrated into the generator and discriminator networks for feature fusion and enhancement. By leveraging adversarial training, SID-TGAN learns more comprehensive representations of sonar images and shows outstanding performance in speckle denoising. Meanwhile, SID-TGAN introduces a new adversarial loss function that combines image content, local texture style, and global similarity to reduce image distortion and information loss during training. Finally, we compare SID-TGAN with state-of-the-art despeckling methods on one image dataset with synthetic optical noise and four real sonar image datasets. The results show that it achieves significantly better despeckling performance than existing methods on all five datasets.
Robust-Adaptive Controllers Designed for Grid-Forming Converters Ensuring Various Low-Inertia Microgrid Conditions
Authors: Pinthurat Watcharakorn , Kongsuk Prayad , Marungsri Boonruang
Published: October 2023

As the integration of renewable energy sources (RESs) and distributed generations (DGs) increases, the need for stable and reliable operation of microgrids (MGs) becomes crucial. However, the inherent low inertia of such systems poses intricate control challenges that necessitate innovative solutions. To tackle these issues, this paper presents the development of robust-adaptive controllers tailored specifically for grid-forming (GFM) converters. The proposed adaptive-robust controllers are designed to accommodate the diverse range of scenarios encountered in low-inertia MGs. The proposed approach applies both the robust control techniques and adaptive control strategies, thereby offering an effective means to ensure stable and seamless converter performance under varying operating conditions. The efficacy of the introduced adaptive-robust controllers for GFM converters is validated within a low-inertia MG, which is characterized by substantial penetration of converter-interfaced resources. The validation also encompasses diverse MG operational scenarios and conditions.
MIARforest Reproducibility and Reliability for Assessing Occupational Risks in the Rainforest
Authors: Lima Killian , Castro Ana C. Meira , Santos Baptista João
Published: October 2023

The Method for the Integrated Assessment of Risks for rainforest (MIARforest) is a specific methodology for assessing the risk of occupational accidents associated with working in native tropical forests. MIARforest was validated for the results’ reproducibility and the reliability of calculated risk levels through the Delphi approach. Two rounds of questionnaires illustrating ten scenarios of activities associated with the logging process in the Eastern Amazon’s native rainforest (Brazil) were presented to forestry and occupational health and safety (OHS) experts. In the first round, the questionnaire was answered anonymously by 55 experts, and in the second, by 46. A percentage of agreement of at least 80% in each question was considered to close the process. Questions that did not meet the criterion in the first round were reassessed in the second round. The obtained results lead to the conclusion that MIARforest, an occupational accident risk assessment tool, has been effectively validated, demonstrating inter-rater reproducibility and reliability in determining risk values. These results highlight the objectivity and reliability of MIARforest.