bluuebunny/crossref_metadata_2025 huggingface dataset:
Pendampingan Revitalisasi Ekstrakurikuler KIR Berbasis Kolaborasi dengan Pendekatan Blended Learning di SMA Negeri 1 Tanggetada
Authors: Ernawati Ernawati , Haris Iyan Nurdiyan , Kharisma Gaby Nanda , Hl Nur Ihsan , Sari Tri Maniarta , Tendrita Miswandi , MGB Fadilah , Muktafia Muktafia
Published: November 2024

The extracurricular activity of Youth Science Club (Kelompok Ilmiah Remaja/ KIR) will not succeed if it is not managed well by the school. The results of the observation indicate that the interest and potential of students in writing scientific papers are quite significant and highly relevant in supporting the strengthening of the Pancasila student profile. However, the KIR activities have not been well accommodated by the school, which underscores the necessity of conducting this community service activity. The focus and objective of this PKM activity is to provide training and support to partners in revitalizing extracurricular KIR activities so that they can be accommodated intensively using a blended learning approach with various real and virtual media. The results of the Community Service Program (Pengabdian kepada Masyarakat/ PkM) with quantitative descriptive analysis show that the writing skills of the students at the beginning of the mentoring received an average score of 33.15, categorized as very poor, and improved at the end of the mentoring to 63.31, categorized as fairly good. The KIR mentoring teachers also experienced an improvement in their ability to guide students. The results of the descriptive analysis showed that the teachers' understanding at the beginning of the mentoring was an average of 42.22% (categorized as insufficient), and by the end of the mentoring, it increased to 80.67%. (good catageory). Thus, through training and mentoring, they have a better understanding of the appropriate research methodology, effective mentoring techniques, and the use of technology in blended learning. Teachers have the potential to become more effective facilitators in helping students produce quality scientific work. This serves as the foundation for designing the KIR revitalization program with a collaborative and blended learning approach.
Pelatihan Guru PAUD dalam Pembuatan Media Buku Flanel Terintegrasi Kosakata Bahasa Inggris
Authors: Misrita Misrita , Bahing Bahing , Ananda Kartika , Givency Christi , Atalarik Agel
Published: November 2024

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan solusi terhadap permasalahan yang dihadapi mitra. Permasalahan tersebut diantaranya TK Shalahuddin selaku mitra masih sangat jarang memberikan pembelajaran Bahasa Inggris awal bagi anak didik, dikarenakan sekolah tersebut tidak memiliki media pembelajaran yang terintegrasi Bahasa Inggris. Pembelajaran Bahasa Inggris hanya diberikan melalui kegiatan bernyanyi tanpa didukung dengan media pembelajaran atau alat peraga. Untuk mengatasi permasalahan mitra, maka tim pengabdian memberikan solusi yaitu (1) memberikan ketersediaan media pembelajaran yang terintegrasi kosakata Bahasa Inggris bagi anak usia dini berupa buku flanel, sehingga dapat dimanfaatkan dalam proses belajar mengajar terutama dalam pembelajaran Bahasa Inggris awal dan (2) memberikan pelatihan pembuatan media buku flanel yang terintegrasi kosakata Bahasa Inggris kepada guru-guru di sekolah mitra. Hasil dari pelaksanaan kegiatan berupa pelatihan ini menunjukkan 100% guru-guru PAUD di sekolah mitra dapat membuat buku flanel terintegrasi kosakata Bahasa Inggris, sesuai dengan langkah-langkah yang dicontohkan oleh tim pengabdian, dan menghasilkan produk akhir berupa buku flanel terintegrasi kosakata Bahasa Inggris sama dengan contoh produk buku flanel dari tim pengabdian. Berdasarkan hasil pengamatan dan wawancara, menunjukkan antusiasme peserta sangat tinggi dalam mengikuti pelatihan ini, begitu juga dengan anak-anak yang antusias dan tertarik belajar kosakata Bahasa Inggris menggunakan buku flanel terintergrasi kosakata Bahasa Inggris.
Penyuluhan Hidup Sehat dan Pola Makan seimbang Bagi Siswa SMP
Authors: Nova Yulianti  , Widiyarto Sigit , Vernia Dellia Mila , Alifah Siti , Nurisman Husain , Rizkiyah Nur , Suprapto Hugo Aries
Published: November 2024

Penyuluhan hidup sehat dan pola makan seimbang merupakan investasi penting bagi masa depan siswa, baik untuk kesehatan individu maupun masyarakat secara keseluruhan. Penyuluhan juga dapat mencakup cara memilih makanan yang berkelanjutan, membangun kesadaran akan dampak lingkungan dari pilihan makanan, seperti mengonsumsi lebih banyak produk lokal dan organik. .Tujuan kegiatan pengabdian kepada masyarakat di sekolah untuk memberikan wawasan pengetahuan dan praktik baik hidup sehat dan pola makan seimbang. Kegiatn ini didasari oleh banyaknya penderita diabetes dan penyakit degeneratif lainya. Banyak siswa yang mengeluh sakit ketika proses belajar di sekolah. Tim yang terdiri dari 3 institusi berkolaborasi dalam menyiapkan materi dan kegiatan kesadaran hidup sehat. Hasil kegiatan ini mencakup kesadaran,perubahan sikap, dan perubahan pola makan pada siswa. Kegiatan lanjutan masih diperlukan, agar siswa tidak mudah lupa, dan membiasakan kehidupan yang lebih sehat, menjauhi rokok dan melakukan olah raga yang rutin dan cukup. Kegiatan dapat dilanjutkan dengan kegiatan yang menunjang kebugaran, sepeti lomba jalan sehat dan senam bersama di sekolah.
 
Kata kunci: Penyuluhan, hidup sehat, pola makan
 
Abstract
 
Healthy Living And Balanced Eating Counseling For Students
Counseling on healthy living and balanced diets is an important investment for students' future, both for individual health and for society as a whole. Counseling can also include how to choose sustainable foods, building awareness of the environmental impact of food choices, such as consuming more local and organic products. The purpose of community service activities in schools is to provide insight into knowledge and good practices of healthy living and balanced diets. This activity is based on the large number of people with diabetes and other degenerative diseases. Many students complain of pain during the learning process at school. A team consisting of 3 institutions collaborated in preparing materials and activities for healthy living awareness. The results of this activity include awareness, changes in attitudes, and changes in eating patterns in students. Follow-up activities are still needed, so that students do not easily forget, and get used to a healthier life, stay away from cigarettes and do regular and sufficient exercise. Activities can be continued with activities that support fitness, such as healthy walking competitions and group gymnastics at school.
 
Keywords:  Counseling, healthy living, diet
Membangun Kelekatan Emosional dengan Anak: Pelatihan Parenting Positif untuk Orang Tua
Authors: Sagita Dony Darma , Saputri Novi Eka
Published: November 2024

Pelatihan positif parenting di TK Alifa bertujuan untuk meningkatkan pemahaman dan keterampilan orang tua dalam membangun kelekatan emosional yang sehat dengan anak melalui pendekatan pengasuhan yang empatik dan konstruktif. Program ini disusun dengan materi yang mencakup validasi emosi, teknik komunikasi efektif, disiplin positif, serta strategi membangun waktu berkualitas bersama anak. Melalui sesi edukasi, praktik, dan diskusi, pelatihan ini memberikan peserta pengetahuan teoritis dan pengalaman praktis yang relevan dengan tantangan pengasuhan sehari-hari. Hasil evaluasi menunjukkan bahwa sebagian besar peserta mengalami peningkatan pemahaman dan kepercayaan diri dalam menerapkan teknik parenting positif. Beberapa peserta melaporkan adanya perubahan dalam hubungan mereka dengan anak, termasuk interaksi yang lebih harmonis dan pengurangan konflik. Sesi tanya jawab dan diskusi kelompok juga membantu peserta untuk berbagi pengalaman dan saling memberikan dukungan. Kesimpulannya, pelatihan ini berhasil menciptakan dampak positif dalam pola pengasuhan peserta, memperkuat kelekatan antara orang tua dan anak, serta meningkatkan kualitas komunikasi keluarga. Program ini menunjukkan bahwa pendekatan pengasuhan yang didasarkan pada empati dan validasi emosi dapat membantu membangun fondasi yang kokoh bagi perkembangan emosional dan sosial anak. Rekomendasi untuk program ini adalah melanjutkan kegiatan dengan sesi lanjutan dan pembentukan kelompok dukungan orang tua agar penerapan parenting positif dapat terus berkembang dalam komunitas.Kata Kunci : Positif parenting, kelekatan emosional, pelatihan orangtua
Defect crystal structure of α-Na0.5–xR0.5+xF2+2x (R = Dy–Lu, Y) on X-Ray and electron diffraction data. II. Defect structure of the α-Na0.4R0.6F2.2 (R = Ho–Lu, Y) nanostructured crystals
Authors: Sulyanova E. A. , Sobolev B. P. , Nikolaichik V. I. , Avilov A. S.
Published: December 2024

The α-Na0.4R0.6F2.2 crystals (R = Ho–Lu, Y) were studied by X-ray diffraction analysis at 293 and 85 K. A unified cluster model of nanostructured crystals with a fluorite-type structure based on the polymorphism of KR3F10 (R = Er, Yb) was used to model their defect structure. The α-Na0.4R0.6F2.2 matrix component contained Na+ and R3+ in a ratio of 1 : 1. Part of the matrix anions was shifted from 8c to 32f position (sp. gr. Fm3m). Excess R3+ cations formed with Na+ octa-cubic clusters with nuclei in the form of cuboctahedra {F12} formed by interstitial anions at the 48i position. The α-Na0.4R0.6F2.2 cluster component was formed by octa-cubic clusters of type i. The electron diffraction method showed that the clusters had the shape of plates about 5 nm thick with superstructural ordering. Their structural model based on the K0.265Gd0.735F2.47 structure was proposed. For the first time, experimental confirmation of the affiliation of α-Na0.5–xR0.5+xF2+2x to nanostructured crystals was obtained by electron diffraction. When the temperature decreases from 293 to 85 K, the type of cluster component of the defect α-Na0.4R0.6F2.2 structure with R = Ho–Lu, and Y was not change. At 293 K, the boundary of the type change of the defect structure in the α-Na0.5–xR0.5+xF2+2x series was located between R = Dy (with the Z = 66 atomic number) and Ho (with Z = 67). When the temperature drops from 293 to 85 K, the position of the boundary was not change.
Protein of unknown function from variovorax paradoxus with amino acid substitution n174k is able to form schiff base with plp molecule
Authors: Ilyasov I. O. , Minyaev M. E. , Rakitina T. V. , Bakunova A. K. , Popov V. O. , Bezsudnova E. Y. , Boyko K. M.
Published: December 2024

Pyridoxal-5'-phosphate (PLP)-dependent enzymes are one of the most widely represented groups of enzymes in organisms, performing more than 150 different catalytic functions. Based on the three-dimensional structure, members of this group are divided into seven (I-VII) different fold types. Cofactor binding in these enzymes occurs due to the formation of a Schiff base with a conserved lysine residue located in the active site. A recently discovered protein from the bacterium Variovorax paradoxus (VAPA), which belongs to the IV fold type and has significant structural similarity to transaminases, contains an asparagine residue at the catalytic lysine position in the transaminases and, as a result, cannot form a Schiff base with PLP and does not have aminotransferase activity. In this research, a point mutant of VAPA protein with the N174K substitution was obtained and its 3D structure was determined. Analysis of the structural data showed that the introduced mutation restores the ability of VAPAN174K to form a Schiff base with a cofactor.
Bioinformatic and functional analysis of the pSID siderophore biosynthesis plasmid of Rhodococcus pyridinivorans 5Ap
Authors: Mandryk М. I. , Vysotskaya А. А. , Yahorava Yu. V. , Surzhyk D. U. , Larchenka А. Yu. , Vasylenko S. L.
Published: December 2024

Complete genome sequencing of R. pyridinivorans strain 5Ар revealed the pSID plasmid (CP063453.1) 250428 bp in size. The gene responsible for replication of this plasmid is, most probably, dnaB. The genes which may be involved in the replication (dnaB, ssb) and plasmid separation after replication (parA) showed the highest similarity to the determinants located on large (224‒343 kb) plasmids of rhodococci: unnamed1 of R. pyridinivorans YF3, unnamed1 of R. rhodochrous LH-B3, pRJH1 of R. pyridinivorans YC-JH2, pRDE01 of Rhodococcus sp. RDE2, and pRho-VOC14-C342 of R. opacus VOC-14. The pSID plasmid was found to contain two loci responsible for the synthesis of secondary metabolites, one of them determining the synthesis of a polyketide compound (similar sequences have been revealed on plasmids of other rhodococci) and the other one probably determines the synthesis of a siderophore: the genes for biosynthesis of this compound (sid1–5) exhibited the highest similarity (not exceeding 75%) with the sequences from Streptomyces vilmorinianum YP1 (CP040244.1), S. ficellus NRRL 8067 (CP034279.1), Streptomyces sp. NBC00162 (CP102509.1), and some other streptomycetes, while showing no similarity to the known siderophore biosynthesis genes of rhodococci. The locus of the pSID plasmid responsible for the siderophore synthesis had a unique organization, since transcription of the sid5 (iucC) gene occurs in the opposite direction, while in other bacteria it belongs to an operon and is located at one of its termini. Inactivation of the sid1 gene was found to result in decreased antagonistic activity of R. pyridinivorans 5Ар against plant-pathogenic bacteria P. carotovorum 2.18, lower resistance to iron and cadmium ions and arsenate, as well as in emergence of phytotoxic properties against radish, while wild-type bacteria exhibit plant growth-promoting activity.
Structure of the regulatory region of nitrile hydratase genes in Rhodococcus rhodochrous М8, a biocatalyst for production of acrylic heteropolymers
Authors: Grechishnikova Е. G. , Shemyakina А. О. , Novikov А. D. , Kalinina Т. I. , Lavrov К. V. , Yanenko А. S.
Published: December 2024

Rhodococcus rhodochrous strain М8 is a platform for development of the biotechnologies for biocatalytic production of acrylic monomers, the raw material for synthesis of acrylic heteropolymers. A genetic system for investigation of the cobalt-dependent transcription of nitrile hydratase genes in this strain was constructed, based the reporter gene of the metal-independent acylamidase from Rhodococcus qingshengii TA37. The cobalt-regulated promoter was shown to be located at a significant distance (~0.5 kb) from nitrile hydratase genes. Excision of the region between the promoter and the nitrile hydratase genes decreased significantly both the promoter activity and the degree of regulation by cobalt. Our results improve the possibilities for rational design of regulated expression cassettes using the promoter of nitrile hydratase genes in Rhodococcus, and for further development of biocatalysts based on these bacteria.
Phylogenetic analysis of phn transporters of Achromobacter insolitus LCu2
Authors: Kryuchkova Ye. V. , Burygin G. L.
Published: December 2024

Phosphonates are alternative phosphorus sources for bacteria. The genome of Achromobacter insolitus strain LCu2 contains three predicted phn clusters of ABC-type phosphonate transporters into the cell. To understand the functional, evolutionary, and ecological role of the phn clusters, phylogenetic analysis of substrate-binding PhnD proteins from strain LCu2 with their homologs in other Achromobacter species and in closely related genera of the family Alcaligenaceae was carried out. The PhnD transporters formed three separate clusters, which indicated the differences in their structural composition. PhnD1 and PhnD2 were present in the genomes of all Achromobacter species and grouped separately from those of other members of the family Alcaligenaceae, which indicated vertical inheritance of the phnD1 and phnD2 genes and their involvement in the life-supporting processes. PhnD3 was found in the genomes of seven Achromobacter species. The phnD3 gene was probably acquired via horizontal transfer or duplication and is induced during adaptation to changing environmental conditions. Maintenance of three structurally different clusters of the phn transporters is probably ecologically advantageous to A. insolitus LCu2, providing for phosphorus retrieval from synthetic and natural organophosphonates as well as other sources.
New Bacteriophage Pseudomonas Phage Ka1 from a Trivia of Lake Baikal
Authors: Fedorova M. S. , Gatina A. E. , Ilyina V. N. , Yadykova L. L. , Dryukker V. V. , Gorshkova A. S. , Kayumov A. R. , Trizna E. Y.
Published: December 2024

The bacteriophage Pseudomonas phage Ka1 was isolated from the water of a tributary of Lake Baikal, in the area of discharge of treated wastewater in the city of Slyudyanka. The bacteriophage genome is 46,092 bp in size. and 50% composition of G + C pairs (AN OP455935.1) has 91% identity with the genome of Pseudomonas phage PSA37, belonging to the Bruynoghevirus from the class Caudoviricetes, which characterizes it as a new representative of Luz24-like phages (Bruynoghevirus). The bacteriophage lyses 62% of clinical isolates of Pseudomonas aeruginosa and is able to increase the effectiveness of gentamicin, ciprofloxacin, imipinem and meropenem by 4–8 times against this bacterium. Integrases, transposases and recombinases are not identified in the genome, which makes Pseudomonas phage Ka1 possible for use in complex therapy of infections caused by P. aeruginosa.
Features of the amino acid composition of gelatins from organs and tissues of a number of farm animals
Authors: Zaitsev S. Y.
Published: December 2024

Gelatins are formed during technological stages of processing animal connective tissue proteins (primarily – collagens) and, from a biochemical point of view, are represented as various polypeptide products. In most cases, gelatins as commercial products are 52.5% made from the skin and bones of cattle; 46.0% – from pig skin and only 1.5% – using other animals. At the beginning of the 21st century, the bulk of gelatins produced are used in food products, about a third in the medical sector, and only about 6% in technical or other industrial applications. Currently, trends towards a healthy lifestyle have intensified, which, along with the religious and cultural traditions of many countries, encourages scientists to look for sources of gelatins that are not related to mammals, but are close to them in physicochemical and functional characteristics. Therefore, recently there has been a tendency that the gigantic volume of production of gelatins from mammals (cattle and pigs) is beginning to decline, although not significantly so far, compared with the relative increase in the production of gelatins from by-products and waste from industrial poultry farming. Moreover, over the past decades, global poultry meat production has increased by more than a third. The optimal content of amino acids (AA) and their ratios in gelatins from cattle and pig skin for their further use is shown. Of course, the AA content in gelatins from pig and cattle skin obtained under different technological conditions may differ significantly. However, in general, these differences are not critical and therefore, sometimes gelatins are obtained from a mixture of animal waste. Recently, in Russia, a composition of protein ingredients from hydrolysates of pig and cattle skin with the addition of dried blood plasma was proposed, which had a significantly better AA composition than in traditional gelatins, which allowed the authors to assume increased biological and nutritional value of the developed product. In addition, a number of authors have discovered an improvement in a number of indicators and biological properties of gelatins from a mixture of animal waste with the formation of a number of specific peptides. Thus, new compositions based on known gelatins with an optimal AA composition are currently being actively developed, leading to improved nutritional and functional properties. The fundamental and applied significance of this review lies in a detailed description of the main studies on the amino acid composition of gelatins and identifying their relationship with the key biochemical and technological indicators of gelatin-based materials.
Boc/Bzl solid phase synthesis of deltorphin II and its analogues without utilization of anhydrous hydrogen fluoride
Authors: Azev V. N. , Mustaeva L. G. , Gorbunova E. Y. , Baidakova L. K. , Chulin A. N. , Maslov L. N. , Mukhomedziyanov A. V. , Molchanov М. V. , Miroshnikov A. I.
Published: December 2024

The toxicity and aggressive nature of hydrogen fluoride have resulted in development of alternative strong Lewis acid-based reagents for final deprotection and cleavage steps in Boc/Bzl peptide synthesis. The acids employed are high-boiling liquids unlike hydrogen fluoride, however most peptides could be quite easily isolated from the cleavage cocktails due to their favorable physico-chemical properties: they are usually precipitated with ether. We found that this simple procedure is not suitable for the isolation of Deltorphin II peptides and its analogues. Therefore we developed alternative isolation methods and successfully purified these peptides. The procedures developed could be utilized in purification of other hydrophibic peptides.
Immobilization of protein probes on biochips with brush polymer cells
Authors: Shtylev G. F. , Shishkin I. Y. , Shershov V. E. , Kuznetsova V. E. , Kachulyak D. A. , Butvilovskaya V. I. , Levashova A. I. , Vasiliskov V. A. , Zasedateleva O. A. , Chudinov A. V.
Published: December 2024

The methods of obtaining a polymer coating from polyvinyl acetate on the surface of polyethylene terephthalate polymer substrates and subsequent production by photoinduced radical copolymerization of acrylate monomers of brush polymers have been studied. Cell matrices with numerous reactive chemical groups were formed by photolithography for subsequent immobilization of proteins. Methods of activation of carboxyl groups on brush polymers attached to the surface of polyethylene terephthalate have been tested. Immobilization of the streptavidin model protein labeled with fluorescent dye Cy3 was performed to test the activation method of carboxyl groups. A variant of immunofluorescence analysis in the format of a biological microchip was tested on the streptavidin – biotinylated immunoglobulin model. Streptavidin, immobilized in brush polymer cells, retains functionality and spatial accessibility for binding to biotinylated immunoglobulin and subsequent manifestation by antibodies fluorescently labeled with Cy5 dye, which opens up prospects for the use of biological microchips with brush polymer cells on polyethylene terephthalate substrates for immunofluorescence analysis of various protein targets.
The use of fluorescence time-resolved microscopy to increase the endoplasmic reticulum selectivity of arylidene-imidazolones fluorogenic dyes
Authors: Gilvanov A. R. , Smirnov A. Y. , Krasnova S. A. , Solovyev I. D. , Savitsky A. P. , Bogdanova Yu. A. , Baranov M. S.
Published: December 2024

Using fluorescence time-resolved microscopy (FLIM), a number of previously synthesized fluorogenic aryliden-imidazolone analogues, predominantly staining the endoplasmic reticulum (ER) of living cells, were studied. It has been shown that the use of this type of fluorescence microscopy can increase the selectivity of ER staining.
Tritium from molecule to biosphere. 2. Approaches to dosimetry
Authors: Antonova E. V.
Published: December 2024

Tritium (3H) has natural and man-made origin. High migration capacity, the presence of different physical and chemical forms, affinity with organic molecules and involvement in metabolic processes in the biosphere attract attention to this isotope in the field of radiation protection of living organisms and humans. The data of 319 publications (230 of them are in the Supplimentary materials) were analyzed based on laboratory and field studies to understand the approaches to the methodology of 3H dose assessment in reference plant and animal organisms specified in Publication 108 of the International Committee on Radiation Protection. The basic principles and features of calculating the absorbed dose rate from inorganic and organic forms of 3H for different levels of biological organization are described. More than half of the studies were identified that are not related to dosimetry issues, but analyze radiobiological effects. Prospects for further research may be associated with a differentiated approach to assessing doses from different forms of 3H, ensuring closer contact between laboratory and field studies, and shifting the focus from the organism level to the populations. The results obtained will find application in formulating problems in the field of radioecology and radiobiology, as well as in improving radiation safety standards associated with the work of existing nuclear industry enterprises and the development of new nuclear technology facilities.
Climate changes in the city of Chernivtsi during global warming
Authors: Nykolaiev Andrii , Hutsul Susanna , Timofieieva Yuliia
Published: December 2024

Climate change trends in Chernivtsi, which began to be observed in the late 1990s, have become clear unidirectional trends. The statistically confirmed time limit for the period of changes in the conditions of thermal regime formation is 1989.

Average annual air temperatures at the climatic norm of 7.9 °C in 1999 crossed the 8.5 °C threshold, and after 2013 they became higher than 10 °C. They increased most intensively during 2008–2023.

In the course of average annual air temperatures, a “step-like” pattern began to emerge, manifested as alternating periods of rapid increase with fluctuations relative to a new higher level.

Temperatures in all months have risen, most notably in winter (by 2.5 °C in January) and summer (by 2.4 °C in July and August). Over the past 20 years, winter temperatures have risen by 2.3 °C and summer temperatures by 2.7 °C.

The rise in air temperatures in Chernivtsi was accompanied by an increase in annual precipitation, a trend that began to be clearly observed after 1963. With the overall increase in annual precipitation, there was an intra-annual redistribution of precipitation, the features of which differed somewhat in 2000–2010 and 2011–2021. During both time periods, precipitation increased in winter and autumn months. In 2000–2010, precipitation in months IV–VI decreased, while in 2011–2021 it was quite noticeable – the amount of precipitation in months VII–IX decreased by 46 mm. With the decrease in precipitation accompanied by rising air temperatures, most of the summer and early fall in Chernivtsi became hot and dry.

As a consequence of the increase in air temperatures in the winter months, the duration of the winter season decreased, and the month of February became, in fact, the first spring month. The dates of the beginning of the destruction and complete melting of the snow cover were observed 10–14 days earlier. On average, the number of days with snow cover decreased by 12 days, and its height decreased by 13 cm.

Changes in the thermal and precipitation regimes have not yet led to an increase in the continental climate of Chernivtsi. The availability of a number of observations of sufficient (35 years) duration, covering the period of climate change with clear unidirectional trends in variations of meteorological elements, necessitates updating the climate norms.

Keywords: global warming, homogeneity of the observation series, climatic norm, temperature amplitude, climatic season, snow cover, aridity and continental climate.
ЗАСТОСУВАННЯ СПЕКТРАЛЬНОГО АНАЛІЗУ ЗВУКОВИХ ХВИЛЬ ДЛЯ ВИЯВЛЕННЯ НЕСПРАВНОСТЕЙ ДВИГУНІВ ВНУТРІШНЬОГО ЗГОРЯННЯ В АВТОМОБІЛЯХ
Authors: МАРКІНА Ольга , МАРКІН Максим , ПРИЙМАК Ростислав
Published: November 2024

У даній статті розглянуто методи вдосконалення безконтактного контролю двигунів внутрішнього згоряння) автомобілів шляхом аналізу звукових сигналів їх роботи. Основною метою дослідження було впровадження новітніх акустичних технологій та спектрального аналізу для виявлення несправностей на ранніх етапах експлуатації двигунів. Проведено експериментальні дослідження із записом звуків роботи двигуна в різних режимах за допомогою стандартних пристроїв, зокрема смартфону Samsung A54. Результати дослідження показали, що спектральний аналіз звукових хвиль є ефективним інструментом для діагностики технічного стану ДВЗ.
У статті представлено графіки звукових хвиль, що ілюструють різні режими роботи двигуна (з увімкненим і вимкненим кондиціонером, на різних передачах), а також графік абсолютних амплітуд для різних режимів. Аналіз даних показав наявність характерних аномалій, які можуть вказувати на несправності, такі як потрапляння повітря в систему двигуна, перевантаження через роботу кондиціонера та аномальні вібрації. Виявлені проблеми потребують додаткової діагностики для підтвердження і своєчасного усунення.
Запропонована методика дозволяє знизити витрати на технічне обслуговування двигунів за рахунок ранньої діагностики, що підвищує конкурентоспроможність підприємств автомобільної промисловості.
ПРОБЛЕМАТИКА ПРОЄКТУВАННЯ ПРОГРАМНИХ СИСТЕМ НА ОСНОВІ ПОДІЙНО-ОРІЄНТОВАНИХ АРХІТЕКТУР (EDA)
Authors: ВОЛОКИТА Артем , ЗОТКІН Кирило
Published: November 2024

У сучасному швидкоплинному світі інформаційні системи повинні обробляти величезні обсяги даних з мінімальною затримкою, що призводить до ускладнення архітектури розподілених систем. Подійно-орієнтована архітектура (ПОА) стала найбільш гнучким та масштабованим рішенням для задоволення зростаючих функціональних вимог, що робить її пріоритетним вибором для проектів з високим навантаженням. Проте впровадження ПОА вимагає ретельного планування на етапі проектування системи, оскільки помилки можуть бути дорогими та призвести до повного збою системи під час великих навантажень.
Ця стаття надає всебічний огляд критичних проблем при проектуванні подійно-орієнтованих архітектур та досліджує ефективні стратегії їх вирішення, забезпечуючи надійну та стабільну роботу системи.
МЕТОД КЕРУВАННЯ ОСВІТЛЕННЯМ У КІБЕРФІЗИЧНІЙ СИСТЕМІ «РОЗУМНИЙ ДІМ»
Authors: АЛЕКСОВ Сергій , ГОВОРУЩЕНКО Тетяна , ВОЙЧУР Олег , ВОЙЧУР Юрій
Published: November 2024

Наразі актуальною проблемою є забезпечення можливості розпізнавання ситуацій та підтримки прийняття рішень у кіберфізичній системі «Розумний дім». Проведене дослідження відомих методів показало, що: наявні рішення передбачають розпізнавання ситуацій та підтримку прийняття рішень лише, як правило, для однієї-двох підсистем кіберфізичної системи «Розумний дім», а також не передбачають можливості оцінювання достатності інформації для прийняття рішень у кіберфізичній системі «Розумний дімк». Тому метою нашого загального дослідження є розпізнавання ситуацій та підтримка прийняття рішень для всіх п’яти підсистем кіберфізичної системи «Розумний дім» із оцінюванням достатності інформації для прийняття всіх рішень шляхом розроблення комплексної системи розпізнавання ситуацій та підтримки прийняття рішень у кіберфізичній системі «Розумний дім», а метою даного дослідження є розпізнавання ситуацій та підтримка прийняття рішень у підсистемі керування освітленням житла кіберфізичної системи «Розумний дім». Розроблений у статті метод керування освітленням у кіберфізичній системі «Розумний дім» дозволяє внести необхідні параметри для подальшого автоматичного функціювання підсистеми керування освітленням житла кіберфізичної системи «Розумний дім» у приміщеннях, а також забезпечує користувачу підсистеми можливість швидкого та зручного налаштування необхідного режиму освітлення. Крім цього, розроблений метод передбачає розпізнавання різних ситуацій у світловому сценарії (достатній світловий потік, недостатній світловий потік, надлишковий світловий потік – згідно із діючими нормами освітлення) та підтримку прийняття рішень щодо освітлення житла згідно із заданим користувачем режимом освітлення (вікдриття/закриття засобів затінення, ввімкнення/вимкнення ламп – в залежності від розпізнаної ситуації).
Трансплантація серця в Україні: досвід одного центру
Authors: Todurov B. M. , Chaikovska S. M. , Kovtun G. I. , Montgomery R , Dellgren G
Published: November 2024

The aim – to show and analyze our own experience of performing orthotopic heart transplantation in patients with end-stage chronic heart failure.Materials and methods. The work retrospectively analyzed the results of 106 cases of orthotopic heart transplantation in adults and children, which were performed by the heart transplantation team of the Heart Institute of the Ministry of Health of Ukraine during 2019–2024.Results. Standard donor hearts were received by 67 (63.3 %) recipients. Marginal donor hearts were used in 39 (36.7 %) cases. In 97 (91.5 %) cases, patients underwent isolated orthotopic heart transplantation. In other cases, coronary artery bypass grafting was performed in 4 (3.75 %) cases, correction of valvular pathology of the donor heart – in 4 (3.75 %) cases, and correction for congenital heart disease – in 1 case. The median duration of ischemia time of the donor heart was 80 (70; 95) minutes. Among the postoperative complications, the most common was a primary graft dysfunction – in 11 (10.4 %) cases. There was no statistical difference in the frequency of postoperative complications between patients with marginal or standard donor hearts. One-year and two-year survival according to Kaplan–Meier was 88.4 ± 4.5 % (95 % CI 81.9–95.5 %) and 86.7 ± 5.7 % (95 % CI 75.9–94.5 %).Conclusions. Our first experience with heart transplantations showed encouraging immediate and medium-term results. Due to the use of marginal donor hearts, we were able to increase the donor organ pool by 40 %. Follow-up is ongoing.
Successful case of using suture-mediated system Perclose ProGlide in TAVI
Authors: Todurov B. M. , Todurov M. B. , Khokhlov A. V. , Stan M. V. , Berestova K. L. , Zelenchuk O. V. , Besaga A. V. , Maruniak S. R.
Published: November 2024

Transcatheter aortic valve implantation (TAVI) has changed the treatment approach for patients with critical aortic stenosis. This clinical case describes the performance of TAVI in a patient with liver cirrhosis, autoimmune hepatitis, coagulopathy, and secondary anemia. Particular attention was paid to complications in the postoperative period. It was necessary to reduce the risks of bleeding and traumatization of blood vessels due to coagulopathy, therefore, to choose a low-traumatic method of closing the postoperative wound and start early activation of the patient in the postoperative period.
PENGARUH KEPEMIMPINAN TRANSFORMASIONAL DAN MANAJEMEN BAKAT DENGAN KETAHANAN ORGANISASI SEBAGAI MEDIASI TERHADAP KINERJA ORGANISASI
Authors: Setyawan Agustinus , Anderson Joenes , Nelson Alden
Published: December 2024

Penelitian ini bertujuan untuk menganalisis kepemimpinan transformasional, manajemen bakat, dan ketahanan organisasi sebagai faktor peningkatan kinerja organisasi pada industri manufaktur. Industri manufaktur dalam setiap aktivitas pekerjaan dan proses produksi pasti mempunyai resiko yang bahaya. Dalam hal ini, banyak industri manufaktur yang kekurangan tenaga kerja sehingga kesulitan mempertahankan dan mencari tenaga kerja yang terampil. Fokus penelitian ini adalah pekerja di industri manufaktur di Kota Batam. Dalam penelitian ini, data dikumpulkan dari responden melalui kuesioner. Sebanyak 198 responden terkumpul. Penelitian ini menggunakan random sampling dalam pemilihan sampel. Program PLS-SEM digunakan untuk menguji penelitian penulis.
UJI MIKROBIOLOGIS SUSU SAPI DENGAN MENGGUNAKAN METODE RESAZURIN PADA BERBAGAI LOKASI PENGUMPUL SUSU SAPI DI KOPERASI PETERNAK SAPI PERAH BAYONGBONG
Authors: Intan Febrian Susanti
Published: December 2024

Tujuan dilakukan penelitian ini adalah untuk mengetahui kualitas susu sapi dengan metode resazurin berdasarkan lama waktu reduksi. Penelitian ini dilakukan pada bulan Juni 2017. Objek dalam penelitian ini adalah susu sapi perah segar hasil peternakan sapi perah di kecamatan Bayongbong. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan pendekatan kuantitatif, yaitu dengan melakukan pemeriksaan terhadap adanya mikroba pada sampel susu dengan menggunakan uji Resazurin dan data yang didapat dari hasil pemeriksaan selanjutnya dianalisis berdasarkan statistik dan literatur. Desain yang digunakan dalam penelitian ini adalah desain eksperimen dengan menggunakan Rancangan Acak Lengkap (RAL). Hasil penelitian diperoleh dari lokasi Bebedahan pada menit ke 15, 30, dan 60 berturut-turut termasuk kriteria “Sangat Baik”, “Sangat Jelek”, dan “Sangat Jelek”; dari lokasi Ciponok, pada menit ke 15, 30, dan 60 berturut-turut termasuk kriteria “Sangat Baik”, “Sangat Baik”, dan “Baik”; dan dari lokasi Olan, pada menit ke 15, 30, dan 60 berturut-turut termasuk kriteria “Sangat Baik”, “Sangat Baik”, dan “Baik”.
PENGARUH PENGGUNAAN MEDIA ANIMASI TERHADAP PENGUASAAN KONSEP SISTEM SIRKULASI PADA SISWA KELAS XI IPA SMA NEGERI 20 GARUT
Authors: Halin Zakiyah  , Diah Ika Putri  , Siti nurkamilah
Published: December 2024

Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh penggunaan media animasi terhadap penguasaan konsep sistem sirkulasi pada siswa kelas XI IPA SMA Negeri 20 Garut. Penelitian ini menggunakan metode quasi eksperimen, pendekatan penelitian menggunakan pendekatan kuantitatif. Sampel dalam penelitian ini yaitu kelas XI IPA 1 sebagai kelas eksperimen dan kelas XI IPA 2 sebagai kelas kontrol yang diambil secara acak kelas. Instrumen yang digunakan sebagai alat pengumpul data berupa test soal objektif pilihan ganda (multiple choice) untuk mengetahui perbedaan penguasaan konsep yang menggunakan media animasi dan media gambar. Berdasarkan hasil analisis data menunjukkan bahwa penguasaan konsep menunjukkan perbedaan kemampuan yang signifikan antara kelas eksperimen dengan kelas kontrol. Pada kelas eksperimen yang menggunakan media animasi rata-rata pre-test nya ( ) dan rata-rata post-testnya ( ). Adapun hasil belajar pada kelas kontrol yang menggunakan media gambar rata-rata pre-test nya ( ) dan rata-rata post- test nya ( ). Berdasarkan hasil analisis data terlihat perbedaan peningkatan rata-rata penguasan konsepantara kelas eksperimen dan kelas kontrol. Pada kelas eksperimen terjadi peningkatan rata-rata sebesar 40,16, sedangkan kelompok kontrol terjadi peningkatan sebesar 31,00. Hasil perhitungan uji Mann Whitney diperoleh nilai Signifikansi= 0,000 < α =0,05. Dapat disimpulkan bahwa terdapat pengaruh pengaruh penggunaan media animasi terhadap penguasaan konsep sistem sirkulasi pada siswa kelas XI IPA SMA Negeri 20 Garut.
PENGARUH PENGGUNAAN METODE PEMBELAJARAN INKUIRI BERBASIS LABORATORIUM TERHADAP HASIL BELAJAR SISWA PADA KONSEP PENCEMARAN AIR
Authors: Euis Karlina
Published: December 2024

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penggunaan metode pembelajaran inkuiri berbasis laboratorium terhadap hasil belajar siswa pada konsep pencemaran air di kelas x SMA Negeri 2 Garut. Sampel dalam penelitian ini yaitu kelas X-5 sebagai kelas eksperimen dan kelas X-4 sebagai kelas kontrol yang diambil secara acak kelas.Penelitian ini dilaksanakan pada bulan mei 2017 di SMA Negeri 2 Garut. Instrument yang digunakan sebagai alat pengumpul data berupa tes, dengan bentuk tes pilihan ganda sebanyak 20 soal dengan 5 option. Berdasakan hasil analisis data menujukkan bahwa : tidak terdapat perbedaan kemampuan penguasaan konsep yang signifikan antara kelas eksperimen dengan kelas kontrol. Pada kelas eksperimen yang menggunakan metode inkuiri berbasis laboratorium rata-rata post-test nya (x = 88,37). Adapun hasil belajar kelas kontrol dengan rata-rata post-testnya (x =48,38). Berdasarkan hasil analisis data akhir menggunakan Mann whitney maka dapat di simpulkan bahwa terdapat pengaruh peningkatan rata-rata penguasaan konsep antara kelas eksperimen dan kelas kontrol. Pada kelas eksperimen terjadi peningkatan rata-rata sebesar 45,5, sedangkan kelompok kontrol terjadi peningkatan sebesar 12,2. Sehingga dapat disimpulkan bahwa terdapat pengaruh penggunaan metode pembelajaran inkuiri berbasis laboratorium terhadap hasil belajar siswa pada konsep pencemaran air kelas x di SMA Negeri 2 Garut.
PENENTUAN KADAR TOTAL TANIN DARI EKSTRAK DAUN BINAHONG (Anredera cordifolia)
Authors: Rismayanti Fatonah  , SRI MULYANINGSIH  , Chevi Ardiana
Published: December 2024

Penelitian ini berjudul “Penentuan Kadar Total Tanin dari Ekstrak Daun Binahong (Anredera cordifolia)”. Tujuan penelitian ini untuk mengetahui keberadaan senyawa tanin dan hasilpenentuan kadar total tanin dari ekstrak daun binahong (Anredera cordifolia). Metode yang digunakan adalah metode deskriptif kuantitatif, dengan metode pengambilan sampel secara purposive sampling, sampel yang digunakan adalah daun binahong (Anredera cordifolia) yang sudah tua. Untuk teknik pengumpulan data dilakukan secara kualitatif dengan uji fitokimia dan kuantitatif dengan uji kadar. Menentukan kadar tanin pada ekstrak sampel dilakukan analisis menggunakan spektrofotometri UV-Vis. Penelitian dilakukan pada bulan Mei - Juni 2021. Ekstraksi tanin pada daun binahong (Anredera cordifolia) dilakukan dengan metode maserasi menggunakan etanol 95%. Pada penelitian ini data dianalisis menggunakan uji regresi linier sederhana. Berdasarkan hasil penelitian, ekstrak daun binahong (Anredera cordifolia) mengandung senyawa tanin yang dibuktikan dengan warna hijau kehitaman dan kadar total tanin dari ekstrak daun binahong (Anredera cordifolia) sebesar 0,230 mg GAE/g ekstrak atau sebesar 23%
Pengaruh Pemberian Bokashi Limbah Tanaman Kubis Dengan Dosis Yang Berbeda (Brassica oleracea L) Terhadap Pertumbuhan Tanaman Tomat Varietas Beef (Solanum lycopersicum)’
Authors: Refina Gemita Ayu
Published: December 2024

Penelitian ini berjudul Pengaruh Pemberian Limbah Tanaman Kubis (Brassica Oleracea L) Terhadap Pertumbuhan Tanaman Tomat varietas beef (Solanum lycopersicum). Tanaman tomat memiliki potensi untuk ditanam di Indonesia mengingat kebutuhan tomat bertambah setiap tahunnya maka perlu adanya penelitian tentang pertumbuhan tanaman tomat untuk menunjang kebutuhan tomat untuk masyarakat tujuan penelitian ini adalah untuk mengetahui pengaruh bokashi limbah kubis hijau (Brassica oleracea l) terhadap pertumbuhan tanaman tomat (Solanum lycopersicum). Metode penelitian yang digunakan dalam penelitian ini adalah metode eksperimen, yaitu percobaan tentang pengaruh bokashi limbah tanaman kubis (Brassica oleracea L) dengan menggunakan rancangan penelitian Rancangan Acak Lengkap (RAL) faktor tunggal yakni dengan pemberian pupuk bokashi dari limbah tanaman kubis (Brassica oleracea l ) dengan dosis pupuk yang diberikan adalah 0 gram,100 gram,200 gram,300 gram dan 400 gram. Berdasarkan hasil penelitian diketahui bahwa : nilai signifikasi 789>0,05 maka Ho diterima dan Ha ditolak maka dapat disimpulkan bahwa tidak terdapat pengaruh pemberian limbah tanaman kubis (Brassica oleracea l ) terhadap tinggi tanaman tomat (Solanum lycopersicum) dan terdapat pengaruh pemberian bokashi limbah tanaman kubis (Brassica oleracea l ) terhadap pertumbuhan jumlah daun dan percepatan tumbuh bunga tanaman tomat ( Solanum lycopersicum) serta konsentrasi yang efektif untuk pertumbuhan jumlah daun dan percepatan pertumbuhan bunga yaitu pada dosis 400 gram.
PENGARUH STRATEGI PEMBELAJARAN GIVING QUESTION AND GETTING ANSWER (GQGA) MELALUI VIDEO CONFERENCE TERHADAP HASIL BELAJAR SISWA PADA KONSEP JAMUR DI SMAN 6 GARUT
Authors: Novia Nurul  , Asep Rohayat  , Diah Ika Putri
Published: December 2024

Penelitian ini bertujuan untuk mengetahui pengaruh strategi pembelajaran giving question and getting answer (GQGA) dan seberapa besar pengaruh strategi pembelajaran GQGA melalui video conference terhadap hasil belajar siswa pada konsep jamur di SMAN 6 Garut. Penelitian ini menggunakan metode Quasi Experimental (eksperimen semu) dengan sifat asosiatif dan menggunakan rancangan eskperimen Non Equivalen Pretest-Posttes Group Design. Sampel dalam penelitian diambil dua kelas dengan cara acak kelompok (Random Sampling) yaitu kelas X MIPA 6 (kelompok eksperimen) dan kelas X MIPA 7 (kelompok kontrol) dengan jumlah siswa sebanyak 53. Data dikumpulkan dengan menggunakan instrument berupa tes objektif (pilihan ganda) sebanyak 35 butir soal. Berdasarkan hasil analisis data, diperoleh skor rata-rata hasil post-test siswa pada kelompok eksperimen (dengan menggunakan strategi pembelajaran GQGA) adalah 83,37 dan skor rata-rata hasil post-test kelompok kontrol (dengan menggunakan strategi pembelajaran konvensional) adalah 70,61. Teknik analisis data menggunakan uji parametrik, yaitu uji hipotesis menggunakan uji t. Hasil penelitian menunjukkan nilai Sig 0,000 < α = 0,05 maka Ho ditolak atau Ha diterima artinya terdapat pengaruh strategi pembelajaran Giving Question and Getting Answer(GQGA) melalui video conference terhadap hasil belajar siswa pada konsep jamur di SMAN 6 Garut. Sedangkan untuk mengetahui seberapa besar pengaruh strategi pembelajaran Giving Question and Getting Answer (GQGA) terhadap hasil belajar siswa menggunakan uji gain ternormalisasi pada kelompok eksperimen yang menggunakan strategi pembelajaran Giving Question and Getting Answer didapatkan nilai rata-rata sebesar 61,9028 dan nilai rata-rata pada kelompok kontrol dengan menggunakan pembelajaran konvensional yaitu sebesar 35,8633. Maka besarnya pengaruh strategi pembelajaran Giving Question and Getting Answer (GQGA) sebesar 26, 0395 angka.
Investigation of the effect of implant crown ratio and material type on the force transmitted to the implant in implant-supported restorations: a finite element analysis study
Authors: Kızılırmak Burcu , Güntekin Neslihan , Mohammadi Reza , Erdoğdu Meryem , Tunçdemir Ali Rıza
Published: November 2024

Aims: The crown implant ratio may pose a problem, especially when short implants are used. This condition is associated with marginal bone loss. Therefore, in this study, it was aimed to evaluate the stresses arising from the bone, implant and its parts and the restoration by finite element analysis (FEA), as a result of comparing a situation with ideal bone support and a similar situation with vertical bone loss. The null hypothesis is that the type of material and crown length chosen for implant-supported restorations will not make a difference in terms of stress on implants of different sizes.
Methods: For this study, 8 mm implants were placed in the 44-46 region and a group with a 3-unit 12 mm length fixed prosthesis and a group with 12 mm implants and a 3-unit 8 mm length fixed restoration were designed. The data of the implant parts were obtained from a implant company (Bilimplant, İstanbul, Turkiye) and placed in the appropriate position within a bone data drawn in the Solidworks 2013 software (Solidworks Corp., USA). Appropriate multi-unit parts were then added and 3-unit restorations were designed with exocad. Necessary arrangements were made in the Geomagic Design X 2020 (3D systems, Morrisville, NC, USA) program, the restorations were given the characteristics of 2 different materials (lithium disilicate and zirconia). Applying a force of 200 N on the occlusal direction, the maximum principal stress values ​​​​occurring in the bone, implant, multi-unit, restoration and occlusal screw were recorded.
Results: Principal stress (Pmax) values recorded on the implant for the 1st premolar were higher on the 12 mm implant (B1 and B2 groups) and lower on the 8 mm implant. For the implant applied to the 1st molar region, higher stress values were observed in the groups with 8 mm implants (A1 and A2 groups), while lower values were observed with 12 mm implants (B1 and B2 groups).
Conclusion: As the crown/implant ratio increases in favour of the implant, the survival of the unit decreases. In addition, it is more appropriate to prefer rigid materials in implant restorations.