bluuebunny/crossref_metadata_2025 huggingface dataset:
FAKTOR-FAKTOR YANG MEMENGARUHI AGRESIVITAS PAJAK
Authors: Tanjung Geraldio , Dewi Sofia Prima
Published: October 2024

This study aims to determine the factors that influence tax aggressiveness in the mining industry listed on the Indonesia Stock Exchange during 2018-2020. This study uses a descriptive research design with purposive sampling method. There are 13 samples with a total of 39 data mining companies. This study uses the Economical Views 12 Student Version application. Data processing techniques using multiple regression analysis. The results of this study indicate that profitability has a negative effect on tax aggressiveness, firm size and managerial ownership have no positive effect on tax aggressiveness and leverage does not. negative effect on tax aggressiveness. With this research, it is hoped that it can improve the company's performance and can add insight in terms of tax aggressiveness. Companies can also consider legally tax aggressiveness to reduce the company's tax burden.
FAKTOR-FAKTOR YANG MEMENGARUHI PROFITABILITAS PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI
Authors: Song William , Susanto Liana
Published: October 2024

This research aims to obtain empirical evidence regarding the effect of the independent variables of liquidity, leverage, and firm size on the profitability of manufacturing companies listed on the Indonesia Stock Exchange during 2018-2020. This study used 68 manufacturing companies which were selected using purposive sampling method. The data processing technique in this study used the Eviews 12.0 SV program. The results of this study indicate that leverage has a significant positive effect on profitability while liquidity and firm size do not have a significant effect on profitability.
FAKTOR-FAKTOR YANG MEMENGARUHI CASH HOLDING
Authors: Sugihwan Bryan Adithya , Susanto Liana
Published: October 2024

This study aims to obtain empirical evidence about the effect of leverage, firm size, profitability, and capital expenditure on cash holding in manufacturing companies listed on the Indonesia Stock Exchange for the 2018-2020 period. The number of samples in this study was selected by purposive sampling method and the valid data were 78 companies. The research data were analyzed using multiple linear regression analysis techniques which were processed with Eviews12 SV software. The results of this study indicate that profitability and capital expenditure have a significant positive effect on cash holding. Firm size does not have a significant effect on cash holding. Leverage has a significant negative effect on cash holding.
PENGARUH GOOD CORPORATE GOVERNANCE DAN INTELLECTUAL CAPITAL TERHADAP FINANCIAL PERFORMANCE
Authors: Pardomuan Reinhard Marthin , Tjakrawala F.X. Kurniawan
Published: October 2024

The purpose of this study is to investigate the governance of manufacturing companies which include the board of directors, audit committee, institutional ownership, and intellectual capital, listed on the Indonesia Stock Exchange (IDX) between 2016 and 2020. This is an empirical assessment of the impact of corporate governance on financial performance. Data collection was carried out on 201 samples of company data selected with the purposive sampling method. The Processing of survey data is supported by the programs SPSS Output program and Microsoft Excel 2019. The results obtained indicate that the board of directors (BOD), institutional ownership (IO), and intellectual capital (VAIC) have a significant influence on financial performance (ROA). The Audit Committee (AC) does not affect the financial performance (ROA). The conclusion of this study is that not only fovernace but also intellecetual capital management needs better governance in order for companies to improve their financial performance.
ANALISIS NILAI PERUSAHAAN DI PENGARUHI TERHADAP PROFITABILITAS, UKURAN PERUSAHAAN DAN KEPEMILIKAN INSTITUSIONAL
Authors: Gautama Jennifer Fernanda , Ekadjaja Agustin
Published: October 2024

This research objectives to obtain empirical evidence on the effect of profitability, company size and institutional ownership on company value. The company value is using the dependent variable and the independent variables used are profitability, company size and institutional ownership. The population in this research are consumer cyclicals (main) companies listed on the Indonesia Stock Exchange in 2016-2020 period. The samples collected using the Purposive Sampling method of 40 companies, which research samples of 27 companies with a total data of 135 samples used. The results of the data used secondary data sourced from the financial statements of companies listed on the Indonesian Stock Exchange. The data analysis technique used in this research is multiple linear regression analysis, t test and F test. This study shows  that 1) profitability has a  positive and significant effect on firm value. 2) firm size has a positive and insignificant effect on firm value. 3) institusional ownership has a positive and in significant effect on firm value.
FAKTOR YANG MEMPENGARUHI CASH HOLDING PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI
Authors: Suhandy Ricky , Rasyid Rosmita
Published: October 2024

The purpose of this research is to examine the effect of leverage, profitability, liquidity, cash flow and dividend payment on cash holding in manufacturing companies listed on the Indonesia Stock Exchange during the year 2017 to 2020. The research used 38 manufacturing companies that were selected using purposive sampling method for a total of 152 sample in four years. The result of the research are profitability have significant positive impact on cash holding, liquidity have insignificant positive impact on cash holding and leverage, cash flow, dividend payment has insignificant negative impact on cash holding.
Proving in cases of fraud committed in the way "Your relative got into trouble"
Authors: Revenko Natal'ya Ivanovna
Published: October 2024

The subject of the study is the process of criminal procedural proof in cases of fraud committed in the way "Your relative got into trouble". This method of fraud is implemented, as a rule, by a group of persons, and the task of the investigator during the preliminary investigation is to collect, verify and evaluate the totality of evidence indicating a certain form of complicity in the commission of a crime. Based on the analysis of criminal cases, a typical set of ideal and material traces is investigated, which are recorded by the investigator in the appropriate types of criminal procedural evidence provided for in Part 2 of Article 74 of the Criminal Procedure Code of the Russian Federation. This body of evidence gives the investigator grounds to assert that when committing fraud, members of a criminal group plan crimes in advance, assign roles and carry out jointly coordinated activities to implement a criminal plan. The study was conducted using general scientific methods of cognition: analysis, synthesis, deduction, analogy; empirical methods: description, comparison; as well as private scientific methods: legal, sociological, formal legal. The analysis of criminal cases of fraud committed in the way "Your relative got into trouble" allowed us to identify a set of evidence that gives grounds to classify these crimes as committed by a group of persons by prior agreement. At the same time, the paper identifies the problem of inaccessibility to law enforcement agencies of information from the Telegram messenger about the planning and preparation of crimes, which makes it impossible to identify the organizers and other members of the criminal group and does not allow to qualify the actions of accomplices as committed by an organized group. The latter is important from the point of view of bringing to criminal responsibility all members of a criminal group and more precisely qualifying and determining the severity of a crime committed by a group of persons by prior agreement. The above should entail the type and amount of criminal punishment adequate to the activities of an organized criminal group. Only in this case, it is possible to effectively improve the effectiveness of the law enforcement system in preventing and combating this type of fraud.
Strategic planning as an element of management of the development of the pension system of the Russian Federation
Authors: Kovalev Vladislav Alekseevich
Published: October 2024

The object of the study is the pension system of the Russian Federation, the subject is the long-term strategic planning for the development of the national pension system. The purpose of the research is to develop proposals for improving the strategic planning of the development of the pension system of the Russian Federation. Special attention is paid to the structure and key provisions of the Strategy for the Long-term Development of the Pension System of the Russian Federation until 2030 (the "Strategy"), the possibility of assessing its implementation, the comparability of the parameters of the functioning of the Russian pension system and data from the long-term budget forecast and forecasts of socio-economic development of the Russian Federation, the interconnection of the goals and objectives of the Strategy and national development goals of the Russian Federation, which makes it possible to develop and implement a comprehensive and coordinated state policy in the field of pension provision for the population. The author considers the expediency of maintaining the current high-level goals of the Strategy in the context of modern socio-economic parameters and trends in the functioning of the Russian economy. The author proceeds to systematization and comparison of the provisions of normative legal acts that are strategic planning documents, modeling of the volume of pension rights, coefficient, graphical, comparative, vertical and horizontal analysis of pension provision indicators. In the course of the study, it was found that the strategy is being implemented in conditions of imperfection of strategic planning documents in terms of pension provision, characterized by low reliability of forecasts, outdated terminology and weak alignment of medium- and long-term planning documents in terms of goal setting, forecasting and programming, weak alignment with the national development goals of the Russian Federation until 2030 and for the future until 2036 the year, the lack of program-oriented cost management in the compulsory pension insurance system. The strategy does not contain unambiguously interpreted indicators of its implementation, does not take into account a significant change in the macroeconomic situation, the transition to a point pension formula, does not contain an assessment of the risks of its implementation, and indicators of the implementation of many of its tasks are not disclosed in other types of strategic documents. We have proposed a number of principles for developing a long-term plan for the development of the pension system, including risk assessment, internal stabilizers and a phased breakdown of the values of indicators of its implementation, as well as defined guidelines for its long-term development, including limiting the growth of the share of the budget mechanism in the national pension system.
The ideas of resentment and bureaucratic unity in the philosophy of social management
Authors: Vasiukov Rostislav Viktorovich
Published: October 2024

The object of research in this article is social management. The subject of the study is the value–motivational component of organizational relations in the context of general cultural, moral, socio-political trends of modern society. The article focuses on the fundamental socio-philosophical and ethical problems and contradictions revealed in such systems of relations as "organization – employee", "manager – subordinate". The article attempts to show the complex moral and political nature of these relations, to use the Nietzschean concept of resentment to describe the sources of some types of organizational conflicts. In addition, the problems of administrative coercion and violence, bureaucratic pressure on the employee's personality come into view. The author of the article generally supports the semantic line of Erich Fromm's "biophilic" concept, which asserts the need to resist the institutional "necrophilic" influence on personality from post-industrial society.  The methodological basis of the research consists of the vitalistic ideas of Friedrich Nietzsche, Henri Bergson and Gilles Deleuze, the "biophilic" concept of Erich Fromm, the concepts of the "disciplinary society" of Michel Foucault and the "society of control" of Gilles Deleuze, the genealogical method and the concept of resentment by Friedrich Nietzsche and Max Scheler. The novelty of the research lies in the author's attempt to highlight the value-motivational component of modern organizational relations in its connection with the general cultural, moral, socio-political trends of modern society. A significant place in the study is devoted to the systematic consideration of such urgent problems of social management as organizational conflicts, administrative violence, bureaucratic pressure, and resentment of subordinates. In many ways, the author seeks to combine the theoretical lines of existentialism, postmodernism and poststructuralism in their attempt to uncover the fundamental foundations and trends of post-industrial society and further apply them to the study of social management. The necessity of further research of the influence of the sphere of social management on the spiritual and moral state of the individual and society is shown. The possible anthropological risks of current trends in bureaucratization of various spheres of public life are highlighted.
The program bases of scientific and technological cooperation of the EAEU states in the field of remote sensing of the Earth
Authors: Shugurov Mark Vladimirovich
Published: October 2024

The subject of this study is a programmatic method for regulating cooperation and integration of the EAEU member states in the field of development and commercial use of Earth remote sensing technologies and techniques. The author dwells in detail on the state of legal regulation of cooperation between the EAEU member states in the space sector and shows the absence of a special subsystem of the Union's law. Special attention is paid to the analysis of the prerequisites for the development and adoption of the interstate program "Integrated System of the EAEU Member States for the production and provision of space and geoinformation services based on national sources of Earth remote sensing data" for 2021–2025 as a tool to increase the global competitiveness of the Union states in the field of space technologies and the big data economy. The main conclusion of the study is the recognition of this program as an important means to enhance scientific, technological and industrial cooperation between enterprises and organizations from the EAEU countries related to the space industry. The novelty of the research lies in the systematization of the planned results of the implementation of the program not only in relation to the formation of the technological base of the digital economy, but also in relation to achieving the goals of sustainable development. The main contribution of this research is to put forward and substantiate the idea that the successful implementation of the program will not only contribute to the consolidation of scientific and technical cooperation as an independent integration area, but will also contribute to the development of the legal framework of the Union regulating cooperation between the participating States in the field of space exploration and use.
A importância do teste do reflexo vermelho para prevenção de doenças oculares no recém-nascido
Authors: Cardoso Heloisa Lemes , Serqueira Jeovana Romero de , Ribeiro Neto Ana Gabriela Almeida , Marsura Ana Maria , Matias Filho Antônio Taciano , Freitas Francarlos Alves de , Teixeira Junior Marcos Antônio de Castro , Coimbra Rafael Borges , Lobo Anna Elisa Ferreira , Vilela Maria Eduarda Fonseca
Published: October 2024

Objetivo: Compreender as dimensões do teste do reflexo vermelho na prevenção e diagnóstico das doenças oculares nos recém-nascidos. Métodos: Trata-se de uma revisão integrativa. Foram utilizadas as bases de dados BVS, PubMed e Scielo, com os descritores “Teste do reflexo vermelho” e “Teste do Olhinho”, em inglês e português. Os critérios de inclusão foram artigos que permitiam o acesso completo ao material, artigos científicos publicados nos últimos 10 anos, publicações nacionais e internacionais. Para critérios de exclusão, foram descartados materiais que não permitiam o acesso completo por serem pagos ou indisponíveis, artigos publicados fora do período estabelecido previamente, monografias e artigos que descreviam outro tipo de triagem neonatal. Resultados: Já com a leitura aprofundada, dos 33 artigos, foram descartados 10 em duplicidade, 16 que não permitiam o acesso completo e que direcionavam com ênfase em outros tipos de triagem neonatal. Resultando em um banco final de 7 artigos que descreviam a importância da realização do teste do reflexo vermelho para prevenção de doenças oculares e cegueira infantil. Considerações finais: Pode-se considerar que o teste do reflexo vermelho é uma ferramenta essencial para a prevenção de doenças oculares, porém, também são necessários protocolos para que ele seja realizado.
Pacientes domiciliados em uso de cateter vesical em um município do interior do Estado de São Paulo
Authors: Itáo Patricia Malagutti Meneghetti , Cruz João Carlos Leite da , Santos Gabriel Xavier , Mazzo Alessandra
Published: October 2024

Objetivo: Caracterizar os pacientes domiciliados que estão em uso de cateter urinário de demora e/ou intermitente num município do interior do estado de São Paulo. Métodos: Trata-se de um estudo de coorte, retrospectivo realizado após autorização ética. Foram inclusos no estudo os pacientes domiciliados que utilizam ou utilizaram o cateterismo urinário de demora e/ou intermitente atendidos pelo serviço de assistência domiciliar (AD) no local, de janeiro de 2018 a dezembro de 2022. Os dados foram analisados no Microsoft Excel® e coletados dos sistemas de gestão do município e dos prontuários do serviço de AD. Resultados: Entre os 3353 pacientes atendidos, 88 utilizaram cateter urinário e 68 foram inclusos no estudo.  Os resultados demonstraram que quase a totalidade são cuidados por mulheres, fazem uso do cateter de demora, por motivos justificados nas suas condições clínicas. Destaca ainda que passam em média muito tempo com o cateter e que há complicações associadas, a mais prevalente é a infecção de trato urinário. Conclusão: A assistência ao usuário de cateter urinário no município tem lacunas, dentre estas, o preenchimento dos prontuários; sendo necessários investimentos no uso de evidências, em tecnologias e na capacitação de equipe, pacientes e familiares.
Melatonin as a Noble approach for un-cooperative child –An observational study
Authors: Gupta Sonal , Patra Abhinandan , Das Asmita
Published: October 2024

Objectives:

Melatonin is a naturally occurring hormone. It is secreted from the pineal gland in the human body. It is also used for preoperative anxiolysis and sedation. Thus, this study aims to evaluate the before and after effects of melatonin medication on sedation, anxiety, and cognitive and psychomotor functions before and after dental procedures.

Materials and Methods:

A total of 45 patients aged between 4 and 8 years scheduled to undergo dental treatment were randomly assigned for medication administration to evaluate changes in behavior, anxiety, orientation, and sedation scale between pre- and post-medication. Data were analyzed using a paired t-test and Wilcoxon test, and P < 0.05 was considered statistically significant.

Results:

Cognitive scores and anxiety scores were decreased significantly, and sedation scores were increased significantly after 60 min of melatonin medication. There were significant differences in trail-making test scores between premedication and 60 min after melatonin medication.

Conclusion:

Thus, it can be used as a potent premedication drug in children as an anti-anxiety drug.
Safety Assessment of a SIER Conditioning Method Based on SIER Dehydration (Dewatering)
Authors:   JSC “All-Russian Research Institute for Nuclear Power Plants Operation”, Petrov S. S. , Gomenyuk I. V. ,   JSC “All-Russian Research Institute for Nuclear Power Plants Operation”, Kornyushkina O. V. ,   JSC “Concern Rosenergoatom”, Matvеenko A. V. ,   JSC “Concern Rosenergoatom”, Rodin A. V. ,   Federal State-Funded Institution Scientific and Technical Center for Nuclear and Radiation Safety, Shkurygin D. M. ,   National Research Centre “Kurchatov Institute”, Shkurygin P. M. ,   National Research Centre “Kurchatov Institute”
Published: October 2024

The paper considers fire and explosion hazards (FEH) inherent in the conditioning of spent ion exchange resins (SIER) referred to intermediate- and low-level waste categories based on the dehydration method. It evaluates the feasibility of its application and demonstrates the compliance of the dehydrated SIER with waste acceptance criteria for disposal. It considers the processes responsible for potentially fire-explosive gas generation evolving along with the dehydration of model radioactive waste (RW) solutions in the form of SIER with an account taken of their chemical composition in storage tanks at NPP. The paper also discusses the potential self-ignition of dehydrated SIER after the RW package is formed.
Koncepcja zrównoważonego rozwoju w systemach produktowo-usługowych
Authors: Nowakowska Paulina
Published: October 2024

Współczesny świat staje przed nieustannie rosnącymi wyzwaniami związanymi ze zrównoważonym rozwojem, które obejmują zmiany klimatyczne, degradację środowiska naturalnego oraz nierówności społeczne. W odpowiedzi na te wyzwania coraz więcej organizacji z różnych sektorów gospodarki włącza koncepcję zrównoważonego rozwoju w swoje strategie zarządzania. Jednym z obszarów, gdzie ta koncepcja znalazła zastosowanie, są systemy produktowo-usługowe (PSS).
Systemy produktowo-usługowe, czyli PSS, to innowacyjne podejście projektowe, które koncentruje się na połączeniu tradycyjnych produktów z usługami w celu dostarczenia klientom wartości końcowej. W kontekście zrównoważonego rozwoju PSS oferuje obiecujące możliwości ograniczania negatywnego wpływu produktów na środowisko poprzez przedłużenie ich żywotności, zwiększanie efektywności wykorzystania zasobów oraz promowanie modeli konsumpcji opartych na dostarczaniu usług.
Niniejszy artykuł ma na celu przedstawienie koncepcji zrównoważonego rozwoju w kontekście systemów produktowo-usługowych oraz analizę rozwiązań, korzyści i wyzwań, związanych z zastosowaniem PSS w osiąganiu celów zrównoważonego rozwoju.
Przestępczość gospodarcza jako wyzwanie dla polskiego sektora bankowego
Authors: Maksymiuk Julia
Published: October 2024

The article analyses the growing challenges of money laundering, loan defrauding and bribery as forms of economic crime for the Polish banking sector. We learn that the development of technology favours criminals, enabling them to use advanced tools. The need for effective cooperation between the banking sector, law enforcement and regulators is pointed out, suggesting investment in advanced transaction monitoring systems, cyber-security training and constant updates to security procedures.
Фрагменты транспортной РНК при клеточном старении, индуцированном стрессом эндоплазматического ретикулума
Authors: Зайченко Д.М. , Пасько А.Ю. , Микрюкова А.А. , Астафьева Я.Р. , Малахо С.Г. , Кубатиев А.А. , Московцев А.А.
Published: October 2024

Транспортная РНК играет ключевую роль в жизнедеятельности клетки, обеспечивая процесс декодирования генетической информации в белковом синтезе. Как показывают последние исследования, молекула тРНК может выполнять другие функции благодаря процессингу. Расщепление пре-тРНК и зрелой тРНК приводит к образованию различных некодирующих РНК, среди которых так называемые половинки тРНК (tRNA halves), также известные как индуцированные стрессом РНК (stress-induced tRNA), tRNA-derived или tiRNA. Описаны также меньшие фрагменты тРНК (tRFs). Характерным примером «двойного назначения» тРНК является разрезание активируемой при клеточном стрессе нуклеазой ангиогенин тРНК в антикодоновой петле с генерацией половинок, из которых 5’-фрагменты опосредуют временное выключение трансляции при стрессе. Ранее нами было впервые показано увеличение содержания tiRNA при остром стрессе эндоплазматического ретикулума и способность хронического стресса ЭПР приводить к формированию фенотипа клеточного старения. В работе с помощью высокопроизводительного секвенирования впервые анализируется профиль фрагментов тРНК при ЭПР-стресс-индуцируемом старении и сопоставляется с профилем при репликативном старении. Обнаружен ряд общих фрагментов тРНК для этих двух состояний. Они потенциально могут использоваться в качестве маркеров процессов клеточного старения.

Transfer RNA plays a key role in the cell, providing the process of decoding genetic information. Recent research shows that the tRNA molecule can perform other functions due to processing. Cleavage of pre-tRNA and mature tRNA leads to the formation of various non-coding RNAs, among which are so-called tRNA halves, also known as stress-induced tRNA, tRNA-derived or tiRNA. Smaller tRNA fragments (tRFs) have also been described. A typical example of «dual purpose» tRNA is the cutting of tRNA in the anticodon loop by cellular stress-activated nuclease angiogenin, generating halves, of which the 5’ fragments mediate temporary translation shutdown under stress. Previously, we demonstrated an increase in tiRNAs during acute endoplasmic reticulum stress and the ability of chronic ER stress to lead to the formation of a cellular senescence phenotype. In this work, using high-throughput sequencing, the profile of tRNA fragments during ER stress-induced cellular senescence is analyzed for the first time and compared with the profile during replicative senescence. A number of common tRNA fragments have been found for these two conditions. They can potentially be used as markers of cellular senescence.
Анализ картографических материалов, размещенных в библиотеке «Московской электронной школы»
Authors: Воронова Т.С.
Published: October 2024

В преподавании географии работа с картой — один из основных видов деятельности. В статье сделан обзор и анализ картографических материалов, размещенных в библиотеке «Московской электронной школы» (МЭШ), их виды, принципы размещения в каталоге, достоинства и недостатки. Важную роль играет качество, степень информативности и достоверность карт.

In teaching geography one of the main activities is working with the map. The article provides an overview and analysis of cartographic materials placed in the library of the Moscow electronic school (MES), their types, principles of placement in the catalog, advantages and disadvantages. An important role plays the quality, degree of information and reliability of maps.
Американский музыкальный минимализм в контексте идеологии «новых левых»
Authors: Кром А.Е.
Published: October 2024

Статья посвящена проблеме рецепции идей молодежного движения «Новых левых» основоположниками и последователями американского музыкального минимализма. Формирование минималистского движения на рубеже 1950-х – 1960-х годов предопределило его открытость влиянию контркультуры, которая оказала сильное воздействие на мировоззрение родоначальников минимализма – от погружения в буддизм, увлечения медитативными практиками и психоделикой до обращения к актуальной социальной проблематике. На примере документального музыкального видео-театра Стива Райха («Пещера», «Три истории»), CNN-опер Джона Адамса («Никсон в Китае», «Смерть Клингхоффера»), ряда опер Филипа Гласса в статье рассматриваются характерные особенности преломления идеологии «Новых левых» в театральном творчестве американских композиторов-минималистов. Они обращаются к обсуждению злободневных политических событий; к религиозному подтексту, выводящему представленный материал на новый уровень осмысления; к документальным источникам и хроникам. Композиторы-постминималисты (Дэвид Лэнг, Джулиус Истман, Энн Саутэм, Джон Лютер Адамс) расширяют круг социально значимых вопросов, сформированных «левой» повесткой, затрагивают проблемы гендерной дискриминации, сексуальной идентичности, феминизма, а также сохранения окружающей среды (эко-минимализм)

The article is devoted to the problem of reception of the ideas of the youth movement “The New Left” by the founders and followers of American minimal music. The formation of the minimalist movement at the turn of the 1950s - 1960s predetermined its openness to the influence of the counterculture, which had a strong impact on the worldview of the founders of minimalism - from immersion in Buddhism, passion for meditative practices and psychedelics to turning to actual social issues. On the example of Steve Reich's documentary music video theater ("The Cave", "Three Tales"), John Adams' CNN operas ("Nixon in China", "The Death of Klinghoffer"), a number of Philip Glass's operas, the article examines the characteristic features of the refraction of ideology "The New Left" in the theatrical work of American minimalist composers. They turn to the discussion of topical political events; to religious overtones that bring the presented material to a new level of understanding; to documentary sources and chronicles. Post-minimalist composers (David Lang, Julius Eastman, Ann Southam, John Luther Adams) expand the range of socially significant issues formed by the "left" agenda, touch upon the problems of racial, gender and sexual identity, feminism, and environmental conservation (eco-minimalism)
Александр Веприк и становление консерваторского образования в Советской России
Authors: Векслер Ю.С.
Published: October 2024

Статья посвящена Александру Веприку (1899–1958) ‑ представителю еврейской школы в советской музыке. В 1920-е годы он работает в Секции музыкального образования Главпрофобра и активно участвует в реформировании системы музыкального образования в России. В 1927 году композитор совершает поездку в Австрию, Германию и Францию с целью знакомства с европейской системой музыкального образования. Он планирует пригласить для преподавания в Московской консерватории одного из крупнейших композиторов современности. В качестве возможных кандидатур Веприк рассматривает Арнольда Шенберга, Пауля Хиндемита и Мориса Равеля. Во время своей поездки Веприк встречается и со многими другими музыкантами, издателями, критиками и педагогами. Впечатления от поездки нашли отражение в недавно опубликованной переписке Веприка с Н. Брюсовой, а также в нескольких статьях, написанных по возвращении. Они содержат живые портреты композиторов, изложение их теоретических и эстетических воззрений, а также проницательные наблюдения о характере музыкальной жизни и системе музыкального образования в Европе. Эти ценные материалы не только расширяют наши представления о музыкальной жизни в первом послереволюционном десятилетии, но и дополняют образ Веприка — борца за возвращение к национальным истокам в искусстве

Alexander Veprik, musical education, Arnold Schönberg, Paul Hindemith, Maurice Ravel

The article is dedicated to Alexander Veprik (1899-1958), a representative of the Jewish school in Soviet music. In the 1920s, he worked in the Music Education Section of the “Glavprofobr” and actively participated in the reform of the music education system in Russia. In 1927, the composer traveled to Austria, Germany and France in order to get acquainted with the European music education system. He plans to invite one of the greatest composers of our time to teach at the Moscow Conservatory. Veprik considers Arnold Schoenberg, Paul Hindemith and Maurice Ravel as possible candidates. During his trip, Veprik also meets with many other musicians, publishers, critics and educators. The impressions of the trip were reflected in the recently published correspondence between Veprik and N. Bryusova, as well as in several articles written upon his return. They contain lively portraits of composers, an exposition of their theoretical and aesthetic views, as well as insightful observations about the nature of musical life and the system of musical education in Europe. These valuable materials not only expand our understanding of musical life in the first post—revolutionary decade, but also complement the image of Veprik, a fighter for a return to national origins in art
Джаз в академическом контексте отечественного образования
Authors: Маклыгин А.Л.
Published: October 2024

В статье рассматриваются особенности внедрения джаза в ХХ веке в сложившуюся систему отечественного академического образования. Показаны общие и специфические черты двух «практик», способствовавших как их сближению, так и определенной оппозиционности с точки зрения их педагогической адаптации. Отражена многоликая ценностная рецепция джаза со стороны академических музыкантов. Специально выделен позитивный опыт научного понимания джаза отечественными музыковедами. Выделен корпус деятелей российского джаза, выполнивших исторически важную миссию органичного вживления «новой практики» в учебный мир отечественного образования. Среди них принципиальное внимание уделено созидательной деятельности профессора Нижегородской государственной консерватории им. М. И. Глинки Валерия Николаевича Сырова

The article examines the peculiarities of the implantation of jazz in the twentieth century into the existing system of domestic academic education. The general and specific features of the two "practices" are shown, which contributed to both their rapprochement and a certain opposition in terms of their pedagogical adaptation. The many-sided value reception of jazz by academic musicians is reflected. The positive experience of scientific understanding of jazz by domestic musicologists is specially highlighted. The line of personalities of Russian jazz who have fulfilled the historically important mission of organically implanting "new practice" into the educational world of domestic education has been highlighted. Among them, fundamental attention is paid to the creative activity of Professor Glinka Nizhny Novgorod State Conservatoire Valery N. Syrov
«Приключения обезьяны» Р. Щедрина в контексте направления инструментального театра
Authors: Кривицкая Е.Д.
Published: October 2024

Область инструментального театра всегда интересовала Р. Щедрина. Его пять концертов для оркестра, концерты для фортепиано с оркестром, многие страницы оперных и балетных партитур, камерная музыка необычайно колоритны по тематизму (композитор вкраплял частушки, мелодии популярных песен, джазовые элементы), инструментовке и включают особые приемы работы с оркестром и оркестрантами. Что именно Щедрин почерпнул из сферы инструментального театра, показано на примере его последнего сочинения для симфонического оркестра «Приключения обезьяны». В статье подробно раскрывается жанровый генезис, анализируется литературная основа, описаны приемы театрализации. Щедрин много раз говорил о своем неприятии авангарда, музыки, созданной ради эпатажа или эксперимента. При этом он использовал ряд приемов конкретной музыки, элементы перформанса, но помещал их в иной, академический контекст, создавая любопытный синтез разновекторных стилевых направлений

he field of instrumental theater has always interested R. Shchedrin. His five concerti for orchestra, concerti for piano and orchestra, many pages of opera and ballet scores and chamber music are unusually colorful in terms of subject matter (the composer incorporated ditties, melodies of popular songs and jazz elements), instrumentation and include special techniques for working with the orchestra and orchestra students. What exactly Shchedrin drew from the sphere of instrumental theater is shown on the example of his last work for symphony orchestra, «The Adventures of the Monkey». The article reveals the genre genesis in detail, analyzes the literary basis, and describes the theatricalization techniques. Shchedrin spoke many times about his rejection of the avant-garde, music created for the sake of epatage or experiment. At the same time, he used a number of techniques of concrete music and elements of performance, but placed them in a different, academic context, creating a curious synthesis of different vectors of style
Пародия в массовой музыкальной культуре современности
Authors: Антипова Ю.В.
Published: October 2024

Одной из главных задач массовой культуры является развлекать и удивлять публику, погружать в желанные для нее эмоциональные состояния. Как никогда прежде она характеризуется особым интересом к пародии, объединяющей подражание, развенчание, глумление, издевку. Пародирование в современной массовой музыке сохраняет многие свойства этой древней формы выражения, художественного принципа, жанра: несоответствие стилистического и тематического планов, гиперболизирование, ведущее к трансформации оригинала; агглютинацию. Здесь складываются новые формы взаимоотношений музыки и внемузыкальных компонентов; утверждается самоценность предлагаемых потребителю форм подражаний (симулякров), обесценивающих настоящее и оригинальное; проявляются свойства интертекстуальности. Пародии в музыкальном масскульте могут выполнять роль критики, давать оценку многим явлениям современной культуры, доказывая актуальность оригинала и, одновременно, спекулируя на нем. В статье предлагается классификация пародий (пародия на жанр, стиль, отдельные типажи, различные форматы развлекательного контента, пародии на пласт классической музыки). Доказывается, что пародия реализует многие свойства постмодернизма (стирание граней между элитарным и массовым, ослабленное чувство истории, медиатизация культуры, популистские тенденции многих искусств, коммерциализация культуры) и нередко предстает в эстетически оправданных и художественно ярких образцах.

One of the main tasks of mass culture is to entertain and surprise the public, to immerse it in the emotional states desired by it. As never before, it is characterized by a special interest in parody, which combines imitation, debunking, mockery, and ridicule. Parody in modern mass music retains many of the properties of this ancient form of expression, artistic principle, and genre: discrepancy between stylistic and thematic plans, hyperbolization leading to the transformation of the original; agglutination. Here new forms of relationships between music and extra-musical components are formed; the intrinsic value of the forms of imitation (simulacra) offered to the consumer is affirmed, devaluing the real and the original; the properties of intertextuality are manifested. Parodies in musical mass culture can play the role of criticism, giving an assessment of many phenomena of modern culture, proving the relevance of the original and, at the same time, speculating on it. The article proposes a classification of parodies (parody of genre, style, individual types, various formats of entertainment content, parodies of a layer of classical music). It is proved that parody implements many properties of postmodernism (erasure of boundaries between the elite and the mass, weakened sense of history, mediatization of culture, populist tendencies of many arts, commercialization of culture) and often appears in aesthetically justified and artistically vivid examples.
A conformation-specific approach to native top-down mass spectrometry
Authors: Britt Hannah , Ben-Younis Aisha , Page Nathanael , Thalassinos Konstantinos
Published: October 2024

Native top-down mass spectrometry is a powerful approach for characterizing proteoforms, and has recently been applied to provide similarly powerful insights into protein conformation. Current approaches, however, are limited such that struc-tural insights can only be obtained for the entire conformational landscape in bulk, or without any direct conformational measurement. We report a new ion mobility-enabled method for performing native top-down MS in a conformation-specific manner. Our approach identified conformation-linked differences in backbone dissociation for the model protein calmodulin, which simultaneously inform upon proteoform variations and provide structural insights. We also illustrate that our method can be applied to protein-ligand complexes, either to identify components or to probe ligand-induced structural changes.
Poly(trihydrazino-diphosphine diazide)s (PHPDs): Hybrid Organic-Inorganic Polymers via Staudinger Polycondensation between PN Cages and Organic Diazides
Authors: Abdollahi Maryam , Welsh Erin , Shayan Mohsen , Olivier Anthony , Wilson-Faubert Noemie , Werner-Zwanziger Ulrike , Nazemi Ali , Laventure Audrey , Chitnis Saurabh
Published: October 2024

Organic polymers generally feature 1-dimensional chains or 2-dimensional rings in their backbones since the strain in small hydrocarbon cages (e.g. cubane) and synthetic challenges limit the availability of 3-dimensional units available as monomers. Inorganic cages are less strained owing to their longer and more ionic bonds, and many can be very accessible, offering an inroad into the minimally explored third dimension that is difficult to study with organic systems. However, only two families of inorganic cages – carboranes and polyhedral oligomeric silsesquioxanes (POSS) – have so far been studied and commercialized to capitalize upon the enhanced mechanical and thermal properties resulting from the use of higher dimensionality backbone components. Further exploration of this fundamentally interesting and potentially valuable parameter space requires development of new inorganic cages that are accessible on large scales, stable under ambient conditions, and polymerizable to give air- and moisture-stable materials. Here we report that a readily-assembled and bench-stable PN cage, P(NMeNMe)3P (1), undergoes clean Staudinger polycondensations with organic diazides (7R) to yield air/water-stable, solution-processable, and film-forming linear poly(trihydrazino-diphosphine diazide)s, PHPDs (8R), as a new family of hybrid organic-inorganic polymers. The solubility of PHPDs in organic or aqueous media can be controlled by choice of diazide and backbone architecture, which we rationally modify to access alternating co-polymers (12R-alt-R’) or multi-block copolymers (12R-block-R’). We also show how a tetraphosphorus cage P4(NMe)6 (2), can be used to crosslinking PHPDs to make more robust materials. Thermal analyses show Tg values for PHPDs that are comparable with rigid π-conjugated polymers (up to 152 °C) and, despite a high nitrogen content (up to 32%) and 3 N-N σ-bonds per repeat unit, decomposition temperatures exceeding 200 °C with char yields up to 60%. These data bear out theoretical predictions of high stability arising from the presence of 3-dimensional units in the backbone. As one potential application area, we show that the high char yields and PN content of a polyether based PHPD (8e) can be leveraged for halogen-free flame-retardancy. These results debut new low-carbon hybrid organic-inorganic polymers with an unusual backbone topology, reveal the design rules for controlling their microstructures and mechanical properties, and lay the foundation for future applied studies with PN cages.
Semisynthesis of aged histone H4 reveals robustness and vulnerability of chromatin towards molecular "wear-and-tear"
Authors: Zhang Tianze , Guerra Luis , Berlina Yana , Wilson Jon , Fierz Beat , Müller Manuel
Published: October 2024

Proteins are subject to molecular “wear-and-tear” in the form of spontaneous, non-enzymatic post-translational modifications (PTMs). One such PTM is the formation of the β-linked isomer L-isoaspartic acid (isoAsp) from aspartic acid (Asp) or asparagine residues, which tends to occur in long-lived proteins. Histones can exhibit half-lives on the order of 100 days, and unsurprisingly, isoAsp formation has been observed in nearly every histone family. Delineating the molecular consequences of isoAsp formation in histones is challenging due to the multitude of processes that occur on such time scales. To isolate the effect of specific isoAsp modification thus necessitates precise in vitro characterisation with well-defined substrates. Here, we adapt a protein semisynthesis approach to generate full-length variants of histone H4 in which the canonical Asp at position 24 is replaced by its isoAsp isomer (H4isoD24). This variant was incorporated into chromatin templates, and the resulting constructs were used to interrogate key parameters of chromatin integrity and maintenance in vitro: compaction, nucleosome remodelling, and methylation of H4 lysine 20 (H4K20). Remarkably, despite its disruptive changes to the backbone’s spacing and direction, isoD24 did not dramatically disrupt Mg2+-mediated chromatin self-association or nucleosome repositioning by the remodeller Chd1. In contrast, H4isoD24 significantly inhibited both Set8- and Suv4-20h1-catalysed methylation at H4K20. These results suggest that H4isoD24 gives rise to a complex reorganisation of the chromatin functional landscape, in which macroscopic processes show robustness and local mechanisms exhibit vulnerability to the presence of this mark.
Assembly of the Tricyclic Core of Alopecurone C by Asymmetric Donor/Donor Carbene C–H Insertion
Authors: Shiue Yuan-Shin , Dyer Matthew , Burlow Noah , Soisaeng Nutthakarn , Lamb Kellan , Soldi Cristian , Fettinger James , Tantillo Dean , Shaw Jared
Published: October 2024

ABSTRACT: Two routes to assemble the complete tricyclic core of alopecurone C are described. In the first-generation route, an efficient synthesis of the “eastern” half of the target, including a decagram-scale rhodium-catalyzed C–H insertion reaction, was developed. When this route proved intractable for assembling the final flavanone ring, a successful second-generation route was developed from a flavanone precursor (naringenin) employing a later stage C–H insertion. Although the second route was ultimately unsuccessful for preparation of the final target, it does provide the basis for the efficient assembly of the complete tricyclic core of alopecurone C and related flavonostilbenoid natural products.
Non-Uniform Chiralization of Metal-Organic Frameworks Using Imine Chemistry
Authors: Novotny Balázs Álmos , Majumdar Sauradeep , Ortega-Guerrero Andres , Jablonka Kevin Maik , Moubarak Elias , Gasilova Natalia , Ebrahim Fatmah Mish , Smit Berend
Published: October 2024

Homochiral metal-organic frameworks (MOFs) are exceptional media for heterogenous enantiodifferentation processes. Modifying available achiral structure-bearing MOF scaffolds is a preferred method to extend this class of materials. Reported postsynthetic covalent chiralizations generally lead to uniform, site-specific modifications. The use of chemically versatile modifying agents, like aldehydes, may instead result in the statistical formation of chemically non-uniform anchored products. In addition, use of such modifying agents gives rise to spatial non-uniformities in the radial direction, due to prohibited diffusion through the MOF bulk. The advantageous grain structure formation plus molecular non-uniformity greatly increase the complexity of such systems. The use of such modifying agents, therefore, necessitates a broader, holistic characterization. The present work explores the adaptation of imine chemistry for post-synthetic chiralization. A chiral aldehyde and a chiral ketone are probed on two amine-functionalized MOF substrates - MIL-125 NH2, and UiO-66 NH2. The UiO-66 NH2 modified with the natural product-derived (R)-2,2-dimethyl-1,3-dioxolane-4-carboxaldehyde ((R)-1 aldehyde) is found to have the best performance in terms of reactivity and MOF stability. A comprehensive toolbox of methods was demonstrated to robustly characterize the obtained material. This includes high-resolution accurate mass electrospray ionization mass spectrometry (HRAM-ESI-MS) to reveal the competing reactions that yield a statistical set of oligomer-rich structures. In silico modeling correctly predicts the localization of the modification. The modification is found to be covalent, chiral, and mainly proceeding through imine formation, resulting in a surface enantioselector display formation. Restricted diffusion lengths in the solid phase infer good retention of resolving power in ascending van Deemter régimes in chromatography. Meeting this criterion makes the yielding material a promising potential stationary phase candidate for performant chromatographic enantioseparations.