bluuebunny/crossref_metadata_2025 huggingface dataset:
FEMİNİST KURAM’DA KADININ POLİTİK EKONOMİSİ VE DÖNÜŞÜMÜ
Authors: SAĞLAM Muhammet Ali
Published: June 2020

Feminist kuramın başat öznesi olarak kadının toplumsal hayattaki her türden sorununu gündeme getirmesi modern dönem ideolojik yaklaşımlarıyla tarihsel-düşünsel bir süreklilik içinde gelişmiştir. Siyasal, sosyal ve iktisadi alanda cinsler arası eşitliği savunan feminist kuram esas öznesi olan kadının bu eşitlenme çabasını konu edinen bir içerik oluşturmayı çabalar. Bu çalışmada feminist kuram içinde yer alan çeşitli feminist akımlar şeklinde bir sınıflandırma uygun görülmüştür. Bu sınıflandırmanın öne çıkan belirgin izlekleri dörde indirgenmiş olup bunlar; liberal feministler, marksist feministler, radikal feministler ve ikili sistem kuramcılarıdır.
Doğal haklar doktrini üzerinden kadın öznesini sorunsallaştıran liberal feminist kuramcılar toplumsal cinsiyet eşitsizliğini kapitalizm içi tartışma konusu yapmaktadırlar. Liberal feministler çözümü yine kapitalist sistem içi çözümlerde aramışlardır. Buna karşılık Marksist feministler ise tarihsel materyalist bakış açısıyla yabancılaşma, iş bölümü, sınıf temelli sömürü biçimleri üzerinden feminist kurama katkıda bulunmuşlardır. Yeni toplumsal hareketler bağlamında ortaya çıkan radikal feministler ve ikili sitem kuramcılarının esin kaynakları Marksist kuram olmak ile birlikte onu aşan bir çerçeve ile feminist kuram içinde belirgin bir iz bırakmışlardır. Partiyarkal sistemi tartışmanın merkezine koyan radikal feministler her türden eşitsizliğin bundan kaynaklandığını ve çözümün partiyarkal sistemin ortadan kaldırılması olarak görmüşlerdir. Buna karşın hem kapitalist sistem hem de patriyarkal sisteminin toplumsal cinsiyet eşitsizliğine yol açtığını öneren ikili sistem kuramcıları ise çözüm önerisini bu iki sistemin değiştirilmesi üzerine kurgulamışlardır. Bu çalışmanın esas konusu farklı feminist kuramların toplumsal cinsiyet eşitsizliğinin politik ekonomideki görünümlerine nasıl bir perspektif ile baktıklarını açığa çıkarmaktır. Bu bağlamda kuramcıların metinlerinin analizi üzerinden ve esas olarak ikili sistem kuramcılarının önerisinden hareketle bir çerçeve oluşturulmaya çalışılmıştır.
EMBATES E PERSPECTIVAS DO TRABALHO PEDAGÓGICO COM DESENVOLVIMENTO DE PRÁTICAS DOCENTES
Authors: Althaus Dalvane
Published: June 2020

Este artigo traz alguns resultados de uma tese, que parte da experiência de uma pedagoga no Ensino Superior envolvendo a Clínica da Atividade (CA). A CA é uma abordagem teórica-metodológica que visa provocar transformações em situações de trabalho, tendo o professor como protagonista de sua prática e o pedagogo como organizador do processo. Contudo, para atuar em CA é preciso passar por uma formação adequada, que será discutida neste trabalho. Além disso, neste texto, o leitor encontrará uma amostra de intervenção com CA e breves análises dos resultados para o professor e para o interveniente. Considera-se que é uma prática respeitosa para com o profissional docente, e transformadora da prática do profissional da pedagogia.
Twenty-year experience of examining biopsies of signal lymph nodes in breast cancer
Authors: Semiglazov V. F. , Krivorotko P. V. , Zhiltsova E. K. , Kanaev S. V. , Trufanova E. S. , Krzhivitskiy P. I. , Komyakhov A. V. , Tabagua T. T. , Nikolaev K. S. , Bessonov A. A. , Ivanov V. G. , Gigolaeva L. P. , Ivanova O. A. , Zernov K. Yu. , Dashyan G. A. , Semiglazov V. V. , Emelyanov A. S. , Busko E. A. , Chernaya A. V. , Artemyeva A. S. , Novikov S. N.
Published: June 2020

Biopsy of signal (sentinel) lymph nodes (LN) has been performed at the N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia, for almost 20 years. In the first few years, contrast-visual method (1 % blue isosulfan and triphenyl methane control) was used in 640 patients with early (T1–2N0M0) breast cancer. In 150 patients from this cohort, standard axillary dissection was performed irrespectively of the results of signal (sentinel) biopsy. The rate of false positive responses varied between 4.6 and 6.6 %. Since 2012, radioisotope method of visualization of signal LN with intratumor administration of99mТс-technephyte colloid particles has been used (in 708 patients with T1–3N0M0 breast cancer). This type of signal LN biopsy had the following diagnostic characteristics: sensitivity was 58.9 %, specificity was 96.2 %, diagnostic accuracy was 87.1 %.

In parallel with this study, in 2016 a study of diagnostic accuracy and safety of biopsy of axillary LN after neoadjuvant systemic therapy was started. The study included 263 patients with T1N1–3M0, T2–3N0–3M0, T4N0–1M0 breast cancer. To evaluate clinical status of axillary LN, ultrasound, single-photon emission computed tomography, mammography at baseline and after completion of neoadjuvant chemotherapy ± targeted therapy (trastuzumab) were performed. In some patients, in the recent years a double method of signal LN labeling (radioisotope and fluorescent methods) was used.

In patients with baseline cN+-status, the rate of false positive signal LN biopsy conclusions was 13.6 %, in patients with baseline cN0-status it was 7.7 %.

The study of double contrast of axillary LN and targeted label of metastatic LN prior to neoadjuvant systemic therapy continues. In total, various modifications of biopsy of signal LN were performed in 2,000 patients with breast cancer.

The study protocol was approved by the biomedical ethics committee of N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia.

All patients gave written informed consent to participate in the study.
Morphological basics of ovarian tumor histogenesis
Authors: Novikov F. V. , Luneva I. S. , Mishina E. S. , Mnikhovich M. V.
Published: June 2020

Researches about the origin of epithelial ovarian tumors (EOT) tell about its conception. In particular, the origin of cells from the secondary mullerian system. Also, in the article we examine a new hypothesis that the EOT originates in the epithelium of the fallopian tube (FT) – their contradictoriness and new conception of “precursor escape” which tries to explain the phenomenon of injuries absence of FT by high-grade serous ovarian carcinoma. Carcinogenesis from the FT represents great opportunities for reassessment of clinical data. Also, the article represents the role of stem cells of the surface epithelium of ovaries and FT in EOT carcinogenesis.
NEGOTIATION: STRATEGIC AND TACTICAL ADMISSION
Authors: Albrny Abdarahman
Published: June 2020

In the article it is definite that the negotiations are the process of interaction of several interdependent parties whose purpose is to achieve their own interests. It is Proved that the main achievement in the negotiations is the adoption of appropriate decisions. It is Noted that the solution of the problem is influenced by: relations between the parties; The possibility and reality of the parties ' claims; Personal interests or interests of the team; Effectiveness of intra-group discussions in finding consensus. It has been Revealed that when entering the negotiation process, its participants use different strategies of their management, and the choice of a strategy depends on: the conditions/structure in which negotiations are conducted; Aspiration of the parties to realize each other's interests (ability to listen and be heard); Comprehension and realization of success of negotiations by their participants.
It is Proved that for skillful negotiations it is necessary to have a strategy which is realized in tactics. Communication Tactics is the use of speaking speech skills to build a dialogue within the framework of the implemented strategist. It is Noted that this tactic and the ability to choose in a particular situation psychologically effective techniques and skillfully apply them to this interlocutor.
It has been Revealed that the purpose of negotiations is to develop a correct and proper attitude to the interlocutor by solving the following tasks: establishing contact with a partner; Organization and formation of pleasant atmosphere of communication; A manifestation of interest in mutual proposals; Establishing the wishes of the other party; Providing a "soft" transition to dialogue.
Maintaining Records in Context: A Historical Exploration of the Theory and Practice of Archival Classification and Arrangement
Authors: Trace Ciaran B.
Published: June 2020

In the first of a two-part article, the author examines the negotiated order that formed around the early conception of the purpose and function of archival classification and arrangement. Drawing from the literature that covers the first sixty years of the development of the American archival profession, the article reveals the historical, social, economic, and technological forces, as well as the specific professional circumstances and interests, in which these principles and processes emerged. In doing so, archival classification is presented as an infrastructural tool that is available for, and understandable to, members of the profession. The picture that emerges is one in which notions of classification and arrangement are emblematic of the profession's identity and aspirations, associated with certain configurations of bureaucracy and technology, embodied in tacit and stated knowledge, accomplished and materialized through experiential practice, yet ever emergent and contested in response to changing social and political realities.
Optimizing Earthquake Early Warning Alert Distance Strategies Using the July 2019 Mw 6.4 and Mw 7.1 Ridgecrest, California, Earthquakes
Authors: Saunders Jessie K. , Aagaard Brad T. , Baltay Annemarie S. , Minson Sarah E.
Published: June 2020

The ShakeAlert earthquake early warning system aims to alert people who experience modified Mercalli intensity (MMI) IV+ shaking during an earthquake using source estimates (magnitude and location) to estimate median-expected peak ground motions with distance, then using these ground motions to determine median-expected MMI and thus the extent of MMI IV shaking. Because median ground motions are used, even if magnitude and location are correct, there will be people outside the alert region who experience MMI IV shaking but do not receive an alert (missed alerts). We use 91,000 “Did You Feel It?” survey responses to the July 2019 Mw 6.4 and Mw 7.1 Ridgecrest, California, earthquakes to determine which ground-motion to intensity conversion equation (GMICE) best fits median MMI with distance. We then explore how incorporating uncertainty from the ground-motion prediction equation and the GMICE in the alert distance calculation can produce more accurate MMI IV alert regions for a desired alerting strategy (e.g., aiming to alert 95% of people who experience MMI IV+ shaking), assuming accurate source characterization. Without incorporating ground-motion uncertainties, we find MMI IV alert regions using median-expected ground motions alert fewer than 20% of the population that experiences MMI IV+ shaking. In contrast, we find >94% of the people who experience MMI IV+ shaking can be included in the MMI IV alert region when two standard deviations of ground-motion uncertainty are included in the alert distance computation. The optimal alerting strategy depends on the false alert tolerance of the community due to the trade-off between minimizing missed and false alerts. This is especially the case for situations like the Mw 6.4 earthquake when alerting 95% of the 5 million people who experience MMI IV+ also results in alerting 14 million people who experience shaking below this level and do not need to take protective action.
Stress Changes on the Garlock Fault during and after the 2019 Ridgecrest Earthquake Sequence
Authors: Ramos Marlon D. , Neo Jing Ci , Thakur Prithvi , Huang Yihe , Wei Shengji
Published: June 2020

The recent 2019 Ridgecrest earthquake sequence in southern California jostled the seismological community by revealing a complex and cascading foreshock series that culminated in a Mw 7.1 mainshock. But the central Garlock fault, despite being located immediately south of this sequence, did not coseismically fail. Instead, the Garlock fault underwent postseismic creep and exhibited a sizeable earthquake swarm. The dynamic details of the rupture process during the mainshock are largely unknown, as is the amount of stress needed to bring the Garlock fault to failure. We present an integrated view of how stresses changed on the Garlock fault during and after the mainshock using a combination of tools including kinematic slip inversion, Coulomb stress change (ΔCFS), and dynamic rupture modeling. We show that positive ΔCFSs cannot easily explain observed aftershock patterns on the Garlock fault but are consistent with where creep was documented on the central Garlock fault section. Our dynamic model is able to reproduce the main slip asperities and kinematically estimated rupture speeds (≤2  km/s) during the mainshock, and suggests the temporal changes in normal and shear stress on the Garlock fault were the greatest near the end of rupture. The largest static and dynamic stress changes on the Garlock fault we observe from our models coincide with the creeping region, suggesting that positive stress perturbations could have caused this during or after the mainshock rupture. This analysis of near-field stress-change evolution gives insight into how the Ridgecrest sequence influenced the local stress field of the northernmost eastern California shear zone.
EFECTO INHIBITORIO DE UN EXTRACTO ACUOSO DE HIBISCUS SABDARIFFA LINN, EN LA OXIDACIÓN DE LIPOPROTEÍNAS DE BAJA DENSIDAD (LDL)
Authors: Pacheco Coello Franklin , Ramirez Azuaje Doralys , Orosco Vargas Corymar , Pinto Catari Ibis , Peraza Marrero María
Published: June 2020

Introducción: A nivel mundial el consumo Hibiscus sabdariffa, ha venido creciendo gracias a su contenido rico en compuestos bioactivos como flavonoides y antocianinas. Por medio de sus cálices ha sido utilizada para prevenir y tratar enfermedades degenerativas como el cáncer, anomalías cardiovasculares e hiperlipidemia. Objetivo: Evaluar el efecto antioxidante de un extracto de H. sabdariffa, por medio del ensayo de oxidación de lipoproteínas de baja densidad (LDL) aisladas de plasma sanguíneo. Métodos: Se emplearon cálices deshidratados obtenidos de un cultivo propio, obteniendo un extracto acuso bajo condiciones similares a la forma de consumo habitual. Se determino el contenido de fenoles totales empleando el método de Folin-Ciocalteu. Caracterizado el extracto se evaluó su actividad antioxidante por el ensayo de oxidación de LDL, obtenida de una muestra sanguínea de tres pacientes sin hiperlipidemia. Resultados: Se evidenció una inhibición de la oxidación de LDL estadísticamente significativa del extracto y su respectivo al control en cada una de las muestras ( p<0,05). Conclusiones: estos resultados respaldan que H. sabdariffa, es una alternativa real en el control de la hiperlipidemia y reducción de la oxidación de las LDL, responsable de la formación de la placa de ateroma a nivel de las arterias. Sin embargo el consumo de esta planta debe hacerse bajo condiciones controlados y guiadas por especialistas a fin de obtener los resultados deseados.
Comprehensive study of the composition of fish fat extracts and quantitative criteria for distinguishing standardized omega-3 polyunsaturated fatty acids extracts
Authors: Torshin I. Yu. , Gromova O. A. , Zaychik B. Ts. , Ruzhitsky A. O.
Published: June 2020

Background Effects of drugs and biologically active supplements based on omega-3 polyunsaturated fatty acids (ω3 PUFA) considerably depend on the standardized content of eicosatetraenoic acid (EPA), docosahexaenoic acid (DHA), and other fatty acids in the extracts.Material and methods In this study, we comprehensively examined the composition of 10 ω3 PUFA samples with chromatographic measurement of more than 40 metabolites of fatty acids and other compounds. The data on extract composition were analyzed with current methods of intelligent data analysis (metric condensation method; multidimensional scaling; principal component analysis with axis identification; topology-metrical approach to recognition).Results Quantitative markers were obtained, which allowed separating the standardized ω3 PUFA-based samples (Omacor, Solgar omega-3 700, Femibion Natalker-2, Omega-3 concentrate, Omegamama) from less standardized ones (Fish oil-Teva, Omegatrin, Omeganol, etc.) based on results of a chromatographic analysis of fatty acid composition in the studied samples (EPA+DHA marker, ω6+ω11 marker, and standardization coefficient showing conformity of measured ω3 PUFA levels with the content stated by the manufacturer).Conclusions Among the studied samples, the pharmaceutical product Omacor showed the best values of standardization indexes.
Vasculotoxicity of Chemotherapy: Assessment оf Endothelial Dysfunction Biomarkers’ Levels in Gastric Cancer Patients
Authors: Kirichenko Yu. Yu. , Belenkov Yu. N. , Privalova E. V. , Naymann Yu. I. , Gitel E. P. , Novikova O. V. , Ilgisonis I. S.
Published: June 2020

Aim To evaluate dynamics of biomarkers for endothelial dysfunction (ED), including endothelin-1 (ET-1) and von Willebrand factor (VWF) in patients with stomach cancer (adenocarcinoma) before and after polychemotherapy (PCT); to compare these results with respective values in healthy volunteers and patients with cardiovascular diseases (CVD); to study correlations of the ED biomarkers with indexes of instrumental evaluation of endothelial dysfunction.Material and methods The study included 75 participants, including 25 healthy volunteers (control group), 25 patients with documented CVDs (arterial hypertension + ischemic heart disease), and 25 patients of the main group with histologically documented stage II-IV stomach cancer (adenocarcinoma) who received different courses of PCT with platinum-based agents (oxaliplatin, cisplatin) and fluoropyrimidines (5 fluorouracil, capecitabin). Laboratory measurement of ED biomarkers, computerized nailfold video capillaroscopy (CNVC), and finger laser photoplethysmography (PPG) (methods for noninvasive evaluation of vascular wall and ED), electrocardiography, 24-h ECG Holter monitoring, and echocardiography (EchoCG) were performed for all patients of the main group prior to PCT and within one months after the last course completion. This evaluation was performed once for healthy volunteers and patients of the CVD group upon inclusion into the study.Results In the main group, ET-1 levels were non-significantly lower than normal and did not change during the courses of antitumor treatment (0.95 [0.6; 1.4] and 0.94 [0.7; 1.4] pg /ml (р<0.9) before and after PCT, respectively). Statistically significant differences were found between the control group and oncological patients after the treatment (р<0.04). Levels of VWF remained within the normal range in all examined participants and did not significantly differ between study groups, including oncological patients before and after the specific treatment (р>0.05 for all comparisons). The correlation analysis detected significant correlations of ET-1 levels with functional disorders of microcirculation, ET-1 with the occlusion index (rs=0.56; p=0.005), ЕТ-1 with percentage of capillary restoration (PCR, rs= –0.72; p=0.018) and with the incidence rate of supraventricular extrasystole (rs=0.48; p=0.032).Conclusion The dynamics of ED biomarkers was studied for the first time in patients with stomach cancer receiving a specific antitumor therapy. Although no significant changes in ЕТ-1 and VWF were observed during the PCT (probably due to exhaustion of the endothelial system and a small patient sample), these indexes can be considered as early vasculotoxicity markers due to the presence of significant correlations with indexes of impaired endothelial function according to the results of instrumental evaluation.
Hypertensive Crisis in the Elderly Patients
Authors: Tkacheva O. N. , Kotovskaya Yu. V. , Eruslanova K. A.
Published: June 2020

A hypertensive crisis is a sudden increase in blood pressure (BP) to an individually high level associated with clinical symptoms and target organ damage, in which BP must be reduced immediately. Since 2018 in Europe and since 2020 in Russia, an uncomplicated hypertensive crisis is recommended to be considered as a part of malignant (uncontrolled) arterial hypertension. The clinical picture of increased BP in elderly patients is characterized by nonspecific symptoms even in target organ damage. Management of this group of patients requires a physician to know the patient’s comorbidities and the drugs taken on a regular basis to minimize development of side effects of the administered drugs and their undesirable interaction with the chronic therapy.
Modification of the of the cardiometabolic profile using combined therapy of the angiotensin receptor-neprilysin inhibitor and empagliflozin in comorbid patients with Chronic Heart Failure and type 2 Diabetes Mellitus
Authors: Tsygankova O. V. , Veretyuk V. V. , Mareev V. Yu.
Published: June 2020

Chronic heart failure (CHF) and type 2 diabetes mellitus (DM2) and very common comorbidities with bidirectional, mutually aggravating courses. DM2 is known as an independent risk factor of cardiovascular complications whereas a higher CHF functional class is associated with increased risk of DM2. At present time, hypoglycemic drugs of the gliflozin class and the angiotensin receptor-neprilysin inhibitor (ARNI) are widely discussed in connection with their use in the treatment of patients with CHF and DM. The PARADIGM-HF study investigated effects of long-term treatment of CHF with reduced ejection fraction with presently the only representative of the ARNI class, a single supramolecular complex of valsartan-sacubitril. This medicine has already exceled enalapril at the effect not only on the incidence of nonfatal and fatal cardiovascular events but also on general mortality. Mean age of patients included into that study was 63.8±11.5 years; 21 % of them were females. In real-life clinical practice, physicians more frequently see older patients, and most of them are females, particularly with DM2. On the other hand, sodium-glucose cotransporter-2 inhibitors, including empagliflozin, significantly decreased the death rate and the frequency of CHF exacerbations in patients with DM2 and concomitant cardiovascular diseases, including CHF. This article describes a clinical case of initiating the valsartan-sacubitril treatment in combination with empagliflozin in an elderly female patient with congestive CHF with intermediate ejection fraction (EF) and comorbidities, including a history of myocardial infarction and DM2. Of interest is the rapid positive dynamics of clinical, laboratory (NT-proBNP) and instrumental (echocardiography) markers of CHF. At 3 months, the EF “recovered” from intermediate to preserved during the use of a comprehensive cardio-reno-metabolic approach. Both cardiologists and endocrinologists should definitely consider this approach in managing such patients since current cardiological drugs have additional pleiotropic metabolic effects whereas hypoglycemic drugs, in their turn, influence the cardiological prognosis.
Gut microbiota and systemic inflammation in patients with chronic heart failure
Authors: Vlasov A. A. , Salikova S. P. , Grinevich V. B. , Bystrova O. V. , Osipov G. A. , Meshkova M. E.
Published: June 2020

Aim To study the interrelationship between intensity of chronic systemic inflammation (CSI) with severity of the condition and intestinal microbiocenosis parameters in patients with chronic heart failure (CHF).Material and methods 47 hospitalized patients with symptomatic CHF were evaluated. The following parameters were determined: clinical condition; N-terminal pro-B-type natriuretic peptide (NT-proBNP). C-reactive protein (CRP); serum interleukins (IL) 6 and 10; and intestinal microbiocenosis composition by mass-spectrometry of microbial markers in whole blood. Microbiocenosis indexes were compared in the main group and in 38 outpatient patients with arterial hypertension and ischemic heart disease without CHF.Results Direct, medium-power correlations were found between CRP and IL-6 concentrations and severity of clinical condition (NT-proBNP, ХСН stage, and edema severity) in patients with CHF. Most patients with CHF had lower numbers of bifido-, lacto-, propionic-, and eubacteria, and Clostridium (С.) ramosum and higher numbers of aspergillus. Among CHF patients, the highest indexes of endotoxemia, gram (-) bacteria, cocci, actinomycetes, and microfungi were observed in the group with NT-proBNP from 400 to 2000 pg/ml. Direct correlations were observed for amounts of C. hystolyticum, Pseudonocardia spp., and Aspergillus spp. with IL-6 and IL-10 and unidirectional inverse correlation were observed for these cytokines with Propionibacterium acnes and jensenii, Streptomyces spp., and Nocardia asteroides. In addition, IL-6 concentration was negatively correlated with contents of Staphylococcus aureus, C. difficile, C. ramosum, Eggerthella lenta, and Corynebacterium spp. and was positively correlated with C. propionicum, Moraxella spp. and Flavobacterium spp. Concentration of IL-6 directly correlated with the number of Eubacterium spp. and inversely correlated with numbers of Ruminicoccus spp. and Streptomyces farmamarensis. The amount of Streptomyces farmamarensis negatively correlated with CRP concentrations.Conclusion The study results evidence the significance of intestinal microbial-tissue complex in the pathogenesis of CSI in CHF and allow suggesting this complex as a promising target for therapy.
The сardiometabolic assessment of the glycemic variability in patients with diabetes mellitus: the role of the glucocardiomonitoring
Authors: Chernikova N. A. , Kamynina L. L. , Ametov A. S.
Published: June 2020

Aim To study quantitatively the two-way relationship between parameters of glycemic variability and development of cardiovascular events in patients with type 2 diabetes mellitus (DM) on chronic sulfonylurea (SM) therapy by synchronous, professional glucose and cardiac monitoring.Material and methods The study included 421 patients with type 2 DM on SM therapy. A 5-day synchronous glucose and cardiac monitoring was performed for these patients in a retrospective mode using an iPro2 (Medtronic, USA) continuous glycemia monitoring (CGM) system and Holter monitoring. Glycemic endpoints (CGM-parameters of glycemia variability and integral indexes) and cardiological endpoints (ventricular rhythm disorders (VRD), ST segment depression (dST), and corrected QT interval (QTc)) were evaluated.Results Clear correlations were found between the ST segment depression and the increase in TIR-HYPO index and the length of QTc. The strongest correlation was observed for VRD and the increase in TIR-HYPO. Moderate correlations were observed between VRD and the decrease in TIR-NORMO and between increased variabilities of glycemia (increases in SD and number of glycemia excursions >4 mmol/l/h) and integral indexes (mean CGM-level of glycemia and HbA1c). Elongation of the QTc interval was associated with increased TIR-HYPO, decrease in maximum glycemia, and development of dST.Conclusion The glucose and cardiac monitoring confirmed the close interrelation between the quality of glycemic control and cardiovascular disorders and should be recommended for a wider use in real-life clinical practice for determining the cardiometabolic status of patients and personalization of hypoglycemic therapy.
Editorial
Authors: De Obstetricia y ginecología Federación Colombiana
Published: June 2020

Por creerlo necesario, tanto la Federación Colombiana de Sociedades de Obstetricia y Ginecología (FECOLSOG) como la Sociedad Colombiana de Obstetricia y Ginecología (SCOG).
Patología benigna del cuello
Authors: Ruíz Castillo Jaime , Jaramillo U. Roberto , Ruíz Acevedo Jaime , Pedraza Gaitán Jaime
Published: June 2020

1. El Departamento de Ginecología y Obstetricia de la Facultad de Medicina del Colegio Mayor de Nuestra Señora del Rosario elaboró un estudio retrospectivo basado en 7.100 historias clínicas extractadas de la consulta externa y analizó las Cervicopatías benignas, en relación directa con los datos de 4.210 citologías cervicovaginales tomadas durante el año de 1976 que se relacionan con edad, paridad y anticoncepción, en los Hospitales Universitarios de San José e Infantil "Lorencita Villegas de Santos".2. Flujos siendo el síntoma más frecuente según los diversos autores, solo encontramos 442 pacientes con este padocimiento como causa principal de consulta. Se presenta en la edad reproductiva y no hay diferencia en relación con la incidencia en los dos Hospitales. La causa más frecuente es la triconomiasis y sólo el 50% de las pacientes practican algún método anticonceptivo. 3. Se analizan 895 historias clínicas con diagnóstico de cervicitirs y 75 más de otras patologías benignas de cérvix; se concluye que esta es la cervicopatía más común en nuestro medio, en los que están de acuerdo los autores, consultados.4. Los pólipos, el ectropión, etc. constituyen una patología muy pobremente representada en nuestro estudio; quizá merezca el futuro una mayor insistencia en su investigación.5. El estudio establece factores socio-económicos y culturales determinantes en cierto tipo de patología en cada uno de los Hospitales.
Modificación del injerto libre en agenesia vaginal
Authors: Del Corral G. Fernando , Botero T. Augusto
Published: June 2020

Se presenta una revisión escueta de las técnicas descritas para la creación de neovagina, haciendo un análisis somero de sus beneficios y ventajas.Se presenta la modificación del injerto libre con resultados excelentes en ocho pacientes con Agenesia Vaginal y se ilustra la técnica correspondiente.
La vasectomía como procedimiento ambulatorio en el Salvador
Authors: Henriquez Enrico , Madrigal Vernon , Painter Cole Lynda
Published: June 2020

La experiencia de 200 hombres vasectomizados en la Asociación Demográfica Salvadoreña (ADS), una clínica privada de planificación familiar, muestra que la vasectomía es un método seguro y efectivo de anticoncepción permanente, aceptado por muchas parejas salvadoreñas. Las parejas que solicitaron esterilización masculina en la ADS tenían más años de educación escolar que aquellas que solicitaron esterilización femenina, pero por lo general no habían usado otros métodos anticonceptivos antes de la esterilización. Más de un tercio de los pacientes se enteraron del programa de vasectomía a través de otros hombres previamente esterilizados. La vasectomía probablemente no ha recibido una aceptación más amplia en la América Latina por no haberse ofrecido el procedimiento en mayor escala.
Platforma czasopism Uniwersytetu Opolskiego przykładem synergii w budowaniu otwartego dostępu do publikacji uczelnianych
Authors: Wierzbicka-Próchniak Dorota , Szewczyk-Kłos Danuta
Published: June 2020

Narodowe Centrum Nauki we wrześniu 2018 r. zadeklarowało udział w realizacji Planu S, który przewiduje, że od 1 stycznia 2020 r. wszystkie publikacje naukowe powstałe z udziałem finansowania ze środków publicznych muszą być publikowane w czasopismach Open Access lub na platformach Open Access. Na Uniwersytecie Opolskim trwały już wtedy prace nad uruchomieniem platformy, która zapewniłaby otwarty dostęp do uczelnianych czasopism naukowych. Docelowo umieszczono na niej trzynaście tytułów wydawanych przez uczelnię. Zadanie to powierzono do realizacji Bibliotece Głównej UO jako jednostce koordynującej wszelkie prace związane z jej powstaniem. Jest to kolejna – po repozytorium uczelnianym – forma aktywnego uczestnictwa Biblioteki w realizowaniu polityki otwartego dostępu na opolskiej Alma Mater. Platformę uruchomiono w listopadzie 2018 roku. Prace związane z jej utworzeniem nie zostały jednak jeszcze zakończone. Celem artykułu jest przedstawienie etapów budowy platformy przy udziale redakcji czasopism, wydawnictw uczelnianych, Centrum Informatycznego, firmy zewnętrznej oraz zespołu pracowników Biblioteki. Stanowi on też omówienie zakresu prac, które będą realizowane przez uczestników projektu, tak, aby zapewnić płynne funkcjonowanie platformy i wysoki poziom widoczności zasobów w bazach indeksujących treści naukowe.
LANDSCAPE INTERVENTION DESIGN STRATEGY WITH APPLICATION OF ISLAMIC ORNAMENTATION AT TRUNOJOYO PARK MALANG, JAWA TIMUR, INDONESIA
Authors: Samudro Harida
Published: June 2020

Trunojoyo Park in Malang City is one of the city parks that has a predicate as the best park. The government of Malang city supports this park into a city park that must be visited by the tourists. The problem is trunojoyo park requires a direction of future development by looking at the perception of visitors who visit the park. The purpose of this study is to know the direction of the new design to find the appropriate design criteria in relation to one's response from the perceptions seen. The architectural intervention in the landscape is one way of approaching how to view the perception in the realm of architectural design. In two ways: temporary intervention and permanent intervention, this method looks at how one's response perceives the architectural element as an aesthetic element in which there is an Islamic ornament as one of the objects applied. This study used descriptive research through field observations by giving random questionnaires that were divided into men and women. Analysis and discussion are done by sorting and calculating each variable of choice of the respondent quantitative). They were further evaluated to determine the factors of visitor perception assessment of aesthetics Park City. This study shows that the order and diversity of vegetation, completeness of facilities, security, and comfort of the Park City are the factors of assessment of visitors to the aesthetics of the Park City. This research has benefited from the emergence of new theories regarding the visitor's assessment of the aesthetic City Park.
Characteristic of baltic cod mince Gadus Morhua Callarias washed with electrochemical activated water with different concentration of active chlorine ions
Authors: Andreev M. P. , Galdukevich V. A.
Published: June 2020

The relevance of the above technological process makes it possible to reduce intensity of fish smell and taste, to improve color, to form a more dense structure and to increase shelf life of minced cod. For the first time minced cod was washed by Electrolyzed – water (EW-water) containing various concentrations of active chlorine, as well as free radicals. The influence of different concentration of active chlorine ions on physical and chemical characteristics of washed minced cod was determined. The optimum concentration of active chlorine ions was determined. The amount of removed water-soluble proteins depends on the type of water and the concentration of active chlorine in it. Pure and electrolyzed - water was characterized before and after washing minced cod. The rheological characteristics of minced cod washed by EW - water with different concentrations of active chlorine ions do not change significantly at a concentration in the range from 25 to 150 mg/l. With a concentration of active chlorine ions more than 200 mg / l, the ultimate shear stress increases significantly, the texture of minced cod becomes too dense, which negatively affects the sensory characteristics. Dependence of ratio of protein coefficient and suitability level of minced cod for preparation of high-quality food product was determined. It was found that washing of the minced cod removes water-soluble proteins, which leads to a change in their ratio with salt-soluble proteins, as a result of which the protein coefficient increases by 1.5-2.4 times. The advantage of washing minced cod by electrolyzed – water, which differs in better rheological characteristics compared to minced cod washed with pure water, was justified.
The functional properties of the vegetable filler Melissa officinalis L. in the composition of curd products
Authors: Novak A. I. , Lyashchuk Y. O.
Published: June 2020

The results of the development of a curd functional product with vegetable filler Melissa officinalis L. are presented. An analysis of the health status of the population carried out in recent years by the World Health Organization shows that the world community is facing acute questions related to the need to prevent the so-called “diseases of civilization”, which include diseases of the cardiovascular system, oncology, diseases associated with impaired lipid metabolism and the gastrointestinal tract, al ergii, decreased immunity, disorders of the nervous system. According to experts, many of these diseases leading to death, disability or disability have a steady upward trend. Up to 44% of the population of our country suffer from cardiovascular diseases (as of December 2019), while more than 82% have functional disorders leading to them. Malignant neoplasms and precancerous conditions are observed in 39% of the adult population, diseases of the gastrointestinal tract are found in more than 48% of the working population of the country. The solution to these problems may be the development of functional food products.
Improving the productivity and quality of rabbit meat based on the integrated use of probiotics and sorbents as part of compound feeds
Authors: Kurchaeva E. E. , Vostroilov A. V. , Lytkina L. I. , Shentsova E. S.
Published: June 2020

The purpose of the study is to evaluate the effectiveness of the use of granular compound feeds with the introduction of probiotic preparation «Prostor», «Sporotermin» and sorbent «Fungistat-GPK» for fattening young rabbits. Studies of the effectiveness of full-size granulated feed were conducted on a population of young rabbits at the age of 45 days, selected according to the principle of groups of analogues and divided into 3 groups in the conditions of a private farm "O. V. Kuznetsova" 15 individuals were selected in each group. The live weight of the experimental groups exceeded the control group's peers when they reached age: 75 days by 85.0 and 251.0 g or 3.99 and 11.80%, 90 days - by 225, 0 and 435, 0 g or 9.04 and 17.49 % and 105 days-139.0 and 245.0 g or 4.37 and 7.70 %. The average daily increase in the control group was 26.55 g, in the experimental group 27.70 and 29.56 g, respectively. Hematological indicators of blood in the experimental groups indicate an increase in the number of red blood cells at the end of fattening (5,35-6,49 1012/l), and there is an increase in the total protein content in rabbits of the experimental groups to 75.82 and 75.99 g/l, which exceeds the values of this indicator of the control group by 3.45 and 0.17 g/l or 4.75 and 0.23%. This trend indicates an intensification of metabolic processes and the possible receipt of the largest increases in live weight. It was found that rabbits of the experimental groups had a slaughter yield of 63.01 and 65.03%, which exceeded the values of this indicator (56.84%) of the control group. The inclusion of enriched compound feeds in feed rations will help to improve the safety and productivity of reared rabbits and creates prerequisites for the large-scale use of these feed resources in the conditions of industrial rabbit breeding.
Application of the “fast” gas chromatography method for regular analysis of fatty acids in milk and dairy products
Authors: Zhizhin N. A.
Published: June 2020

The paper presents one of the approaches for identifying fatty acids using gas chromatography, which significantly reduces the analysis time, and is equally effective when compared with the traditional method of studying the fatty acid composition. The determination of the composition of fatty acids today is a guarantee of quality in identifying various conformations and modifications of milk fat, the bioactive properties of individual acids of the omega-3 and omega-6 families, etc. Moreover, this method is time-consuming, therefore, the goal of this work is to optimize the parameters of this methodology for quick and regular analysis of fatty acid composition in laboratories and dairy enterprises. The analysis of the fatty acid composition was carried out using two columns with different stationary phases. A comparative evaluation of the analytical characteristics was carried out on two capillary chromatographic columns: SP-2560 100 ? 0.25 mm ID, 0.2 ?m with a stationary phase FFAP (traditional) and a gas chromatographic column BPX-70: stationary phase 70% cyanopropylphenyl dimethylpolysiloxane, 10 m ? 0.1 m ? 0.20 ?m. Detection was carried out using a flame ionization detector. A mixture of Supelco® 37 FAME Mix fatty acid methyl esters and Sigma-Aldrich methyl decanoate analytical standard was used as the standard. For data processing, the NetChrom software was used, the composition of fatty acid methyl esters was calculated by the internal normalization method. The analysis time of the first column was 49.07 minutes, for the second 8.44, respectively. The use of a stationary phase column of cyanopropylphenyl dimethylpolysiloxane significantly reduced the analysis time when eluting a complex composition of fatty acids. The studies were carried out using modern analytical techniques and arbitration methods of analysis in the laboratory of technochemical control of the All-Russian Scientific Research Institute of the Dairy Industry. This adapted analysis method will be of interest to specialists in the field of laboratory research and processing enterprises.
Fat rendering in an electrochemically activated water environment: technological aspects, safety and quality of the finished product
Authors: Gorbacheva M. V. , Tarasov V. E. , Sapozhnikova A. I. , Kalmanovich S. A.
Published: June 2020

The work is devoted to studying the influence of physical-chemical and mechanical impact on the process of fat rendering in the presence of electrolyte (catholite) in order to develop an algorithm of fat extraction and obtain a high quality product with adjustable melting point. It is determined that the duration of rendering and heat treatment of raw materials have an equal effect on the index of acid number of ostrich fat. The inverse dependence on the hydrogen indicator of the water phase of the catholite, providing a decrease in the acid number of fat, is revealed. Positive dynamics on the indicator of acid number of ready product at fat extraction with pH of the catholite in the range of 10-10,5 irrespective of temperature and duration of process (acid number of fat did not exceed 0,77 mg KON/g) was established. In the course of fat rendering at the temperature of 50-55 ? and pH of the catolyte not lower than 9, it was found that the peroxide number is in the range of 1.56-1.81 mmol of active oxygen/kg, which confirms the inhibitory effect of the electrochemical environment not only on lipolysis, but also on lipid oxidative degradation. The highest yield of rendered fat was observed at the time and temperature of raw material processing, respectively, 60 minutes and 95 ?, pH of catholite is 10. The use of electro-activated liquid allowed to reduce time of fat extraction by half without significant losses in yield and quality of the finished product. With increase of pH of catolite up to 10,5 it was possible to reduce time and temperature of heatering up to 45 minutes and 75 ? correspondingly while maintaining high value of fat yield that confirms efficiency of electrolyte application and also possibility to set conditions and parameters of rendering depending on the objectives sought. Fat, rendered with the help of electro-activated liquid, does not possess toxicity at intragastric injection to laboratory animal, and also irritating and allergic effect during application on mucous membranes and skin
Sugar content, acidity and antioxidant activity in dehydrated blackcurrant
Authors: Barbashin D. I.
Published: June 2020

The main reason for spoilage of berry raw materials is the high water content in it. And in order to increase the shelf life of such raw materials and products based on it, various dehydration methods are used. Osmotic dehydration, considered in this article, is one of the best and suitable methods for increasing the shelf life of berry products, as well as increasing the biological value of the product. This method is preferred relative to other methods of dehydration due to the fact that when it is used in raw materials, more vitamins and minerals are preserved, and the color, aroma and taste of berries are also better preserved. Osmotic dehydration is a process due to the presence of semi-permeable membranes, during which the concentration is balanced. Osmosis takes place during the immersion of fruits in concentrated solutions of osmotically active substances. In such a system, two opposite processes occur: water diffuses from the product into the solution, and the dissolved substance diffuses from the solution into the product. This article discusses the features of the process of osmotic dehydration of blackcurrant berries. Blackcurrant is a promising raw material for processing enterprises. The berry contains a large amount of ascorbic acid, anthocyanins and has a high antioxidant activity. Methods were studied for samples of dried blackcurrant berries (by convection), with preliminary osmotic dehydration with various osmotic agents (sucrose, flower honey), using the following methods: ascorbic acid and antioxidant activity were determined titrimetrically using the Folin-Ciocalteu reagent polyphenols, spectrophotometrically anthocyanins.
Selection of starter cultures of direct application for hard cheeses
Authors: Romanova N. V. , Ivanova E. V. , Terentev S. E.
Published: June 2020

The article describes and presents the results of research in the selection of direct-application ferments containing lactic acid bacteria and lactic streptococci to optimize the production process of hard cheeses "Melkorisunchatyj 1" and "Melkorisunchatyj 2". The research objects were selected starter cultures of direct application of DSS-275 by " Chr. Hansen" (Denmark) and mos 066 C of Sacco s.r.l (Italy). Based on the results of trial workings, recommendations are given for the use of starter cultures to produce hard cheeses with a small pattern. The possibilities of using direct starter cultures in the production of hard cheeses were studied. As objects of research, conditionally named cheeses "Melkorisunchatyj 1" and "Melkorisunchatyj 2", starter compositions and a milk-clotting preparation were selected. For hard cheeses with fine patterns, the most suitable starter cultures are those consisting of a complex of lactic acid bacteria and milk streptococci. To obtain cheeses with improved organoleptic characteristics, direct starter cultures DSS - 275 from Chr. Hansen "(Denmark) and MOS 066 C of the company" Sacco s.r.l "(Italy). Frozen starter cultures were reconstituted in warm milk and then added to the mixture after filling the bath. A solution of the milk-clotting enzyme was introduced after an increase in titratable acidity by 1.3–1.5 ° T. Good quality cheese was obtained at pH 5.5 at the end of self-pressing. For hard cheeses, it is advisable to use starter cultures combining lactic acid and aromatizing microorganisms.