bluuebunny/crossref_metadata_2025 huggingface dataset:
Hit-to-Lead Short Peptides against Dengue Type 2 Envelope Protein: Computational and Experimental Investigations
Authors: Zaidi Norburhanuddin Johari , Abdullah Adib Afandi , Heh Choon Han , Lin Chun-Hung , Othman Rozana , Ahmad Fuaad Abdullah Al Hadi
Published: May 2022

Data from the World Health Organisation show that the global incidence of dengue infection has risen drastically, with an estimated 400 million cases of dengue infection occurring annually. Despite this worrying trend, there is still no therapeutic treatment available. Herein, we investigated short peptide fragments with a varying total number of amino acid residues (peptide fragments) from previously reported dengue virus type 2 (DENV2) peptide-based inhibitors, DN58wt (GDSYIIIGVEPGQLKENWFKKGSSIGQMF), DN58opt (TWWCFYFCRRHHPFWFFYRHN), DS36wt (LITVNPIVTEKDSPVNIEAE), and DS36opt (RHWEQFYFRRRERKFWLFFW), aided by in silico approaches: peptide–protein molecular docking and 100 ns of molecular dynamics (MD) simulation via molecular mechanics using Poisson–Boltzmann surface area (MMPBSA) and molecular mechanics generalised Born surface area (MMGBSA) methods. A library of 11,699 peptide fragments was generated, subjected to in silico calculation, and the candidates with the excellent binding affinity and shown to be stable in the DI-DIII binding pocket of DENV2 envelope (E) protein were determined. Selected peptides were synthesised using conventional Fmoc solid-phase peptide chemistry, purified by RP-HPLC, and characterised using LCMS. In vitro studies followed, to test for the peptides’ toxicity and efficacy in inhibiting the DENV2 growth cycle. Our studies identified the electrostatic interaction (from free energy calculation) to be the driving stabilising force for the E protein–peptide interactions. Five key E protein residues were also identified that had the most interactions with the peptides: (polar) LYS36, ASN37, and ARG350, and (nonpolar) LEU351 and VAL354; these residues might play crucial roles in the effective binding interactions. One of the peptide fragments, DN58opt_8-13 (PFWFFYRH), showed the best inhibitory activity, at about 63% DENV2 plague reduction, compared with no treatment. This correlates well with the in silico studies in which the peptide possessed the lowest binding energy (−9.0 kcal/mol) and was maintained steadily within the binding pocket of DENV2 E protein during the MD simulations. This study demonstrates the use of computational studies to expand research on lead optimisation of antiviral peptides, thus explaining the inhibitory potential of the designed peptides.
Andrographolide Inhibits Biofilm and Virulence in Listeria monocytogenes as a Quorum-Sensing Inhibitor
Authors: Yu Tao , Jiang Xiaojie , Xu Xiaobo , Jiang Congyi , Kang Rui , Jiang Xiaobing
Published: May 2022

Listeria monocytogenes is a major foodborne pathogen that can cause listeriosis in humans and animals. Andrographolide is known as a natural antibiotic and exhibits good antibacterial activity. We aimed to investigate the effect of andrographolide on two quorum-sensing (QS) systems, LuxS/AI-2 and Agr/AIP of L. monocytogenes, as well as QS-controlled phenotypes in this study. Our results showed that neither luxS expression nor AI-2 production was affected by andrographolide. Nevertheless, andrographolide significantly reduced the expression levels of the agr genes and the activity of the agr promoter P2. Results from the crystal violet staining method, confocal laser scanning microscopy (CLSM), and field emission scanning electron microscopy (FE-SEM) demonstrated that andrographolide remarkably inhibited the biofilm-forming ability of L. monocytogenes 10403S. The preformed biofilms were eradicated when exposed to andrographolide, and reduced surviving cells were also observed in treated biofilms. L. monocytogenes treated with andrographolide exhibited decreased ability to secrete LLO and adhere to and invade Caco-2 cells. Therefore, andrographolide is a potential QS inhibitor by targeting the Agr QS system to reduce biofilm formation and virulence of L. monocytogenes.
Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
Authors: Hsieh Ming-Ju , Huang Chih-Yang , Kiefer Rudolf , Lee Shin-Da , Maurya Nancy , Velmurugan Bharath Kumar
Published: May 2022

Foods rich in antioxidants such as lycopene have a major role in maintaining cardiac health. Lycopene, 80% of which can be obtained by consuming a common vegetable such as tomato, can prevent the disturbances that contribute to cardiovascular disease (CVD). The present work begins with a brief introduction to CVD and lycopene and its various properties such as bioavailability, pharmacokinetics, etc. In this review, the potential cardio-protective effects of lycopene that reduce the progression of CVD and thrombotic complications are detailed. Further, the protective effects of lycopene including in vitro, in vivo and clinical trials conducted on lycopene for CVD protective effects are explained. Finally, the controversial aspect of lycopene as a protective agent against CVD and toxicity are also mentioned.
A Comparative Study on Relieving Exercise-Induced Fatigue by Inhalation of Different Citrus Essential Oils
Authors: Tian Lei , Hu Tan , Zhang Shanshan , Zhang Hongyan , Yang Chenxi , Chen Guiting , Pan Siyi
Published: May 2022

Citrus essential oils (CEOs) possess physiological functions due to diverse aroma components. However, evidence for the effects of CEOs on exercise performance and exercise-induced fatigue is limited. The CEOs with discrepancies in components may exert different effects on the amelioration of exercise-induced fatigue. In this study, sweet orange (Citrus sinensis L.) essential oil (SEO), lemon (Citrus limon Osbeck) essential oil (LEO), and bergamot (Citrus bergamia Risso and Poit) essential oil (BEO) were chosen to explore the effect on amelioration of exercise-induced fatigue. Our results demonstrated that SEO and LEO increased the swimming time by 276% and 46.5%, while BEO did not. Moreover, the three CEOs exerted varying effects on mitigating exercise-induced fatigue via inhibiting oxidative stress, protecting muscle injury, and promoting glucose-dependent energy supply. Accordingly, BEO showed the best efficiency. Moreover, the GC-MS and Pearson correlation analysis of BEO showed that the contents of the major components, such as (±)-limonene (32.9%), linalyl butyrate (17.8%), and linalool (7.7%), were significantly positively correlated with relieving exercise-induced fatigue.
A Study on Pre-Oxidation of Petroleum Pitch-Based Activated Carbons for Electric Double-Layer Capacitors
Authors: Kim Jong-Woo , Kim Dae-Won , Lee Seul-Yi , Park Soo-Jin
Published: May 2022

Electric double-layer capacitors (EDLCs) are an excellent electrochemical energy storage system (ESS) because of their superior power density, faster charge–discharge ability, and longer cycle life compared to those of other EES systems. Activated carbons (ACs) have been mainly used as the electrode materials for EDLCs because of their high specific surface area, superior chemical stability, and low cost. Petroleum pitch (PP) is a graphitizable carbon that is a promising precursor for ACs because of its high carbon content, which is obtained as an abundant by-product during the distillation of petroleum. However, the processibility of PP is poor because of its stable structure. In this study, pre-oxidized PP-derived AC (OPP-AC) was prepared to investigate the effects of pre-oxidation on the electrochemical behaviors of PP. The specific surface area and pore size distribution of OPP-AC were lower and narrower, respectively, compared to the textural properties of untreated PP-derived AC (PP-AC). On the other hand, the specific capacitance of OPP-AC was 25% higher than that of PP-AC. These results revealed that pre-oxidation of PP induces a highly developed micropore structure of ACs, resulting in improved electrochemical performance.
Red Orange and Bitter Orange IntegroPectin: Structure and Main Functional Compounds
Authors: Scurria Antonino , Sciortino Marzia , Garcia Ana Rosa , Pagliaro Mario , Avellone Giuseppe , Fidalgo Alexandra , Albanese Lorenzo , Meneguzzo Francesco , Ciriminna Rosaria , Ilharco Laura M.
Published: May 2022

DRIFT, HPLC-MS, and SPME-GC/MS analyses were used to unveil the structure and the main functional compounds of red (blood) orange (Citrus sinensis) and bitter orange (Citrus aurantium). The IntegroPectin samples show evidence that these new citrus pectins are comprised of pectin rich in RG-I hairy regions functionalized with citrus biophenols, chiefly flavonoids and volatile molecules, mostly terpenes. Remarkably, IntegroPectin from the peel of fresh bitter oranges is the first high methoxyl citrus pectin extracted via hydrodynamic cavitation, whereas the red orange IntegroPectin is a low methoxyl pectin. C. aurantium IntegroPectin has a uniquely high concentration of adsorbed flavonoids, especially the flavanone glycosides hesperidin, naringin, and eriocitrin.
Strategies for Generating Footsteps of Biped Robots in Narrow Sight
Authors: Yoon Sung-Joon , Cho Baek-Kyu
Published: May 2022

In this paper, we present a strategy for a legged robot to stably cross cinder blocks with a limited area acquired from a camera. First, we used the point cloud acquired from the camera to detect the planes and calculate their centroids and directions. This information was used to determine the position and direction of the foot to which the robot should go. Existing A*-based footstep planners require a global map to reach the goal from the start and do not generate a path if there is no solution to the goal due to completeness of A*. In addition, if the map is not updated while moving the path, it is vulnerable to changes in the object position. Our strategy calculates the footsteps that the robot can walk in a limited camera area without securing a global map. In addition, it updates the local map information every walking step so that it quickly recognizes nearby objects and finds a path that can move. While the robot is walking, objects may not be detected due to the narrow camera field of view. In addition, even if an area for the robot to land is found, a situation in which the robot’s legs collide may occur. We present a strategy to solve this problem using previous landing data. In the experimental environment composed of several patterns, the performance was verified by stably walking on the blocks without collision between the robot’s legs.
On the Effect of Interferences on X-Band Radar Wave Measurements
Authors: Chernyshov Pavel , Hessner Katrin , Zavadsky Andrey , Toledo Yaron
Published: May 2022

X-band radars are in growing use for various oceanographic purposes, providing spatial real-time information about sea state parameters, surface elevations, currents, and bathymetry. Therefore, it is very appealing to use such systems as operational aids to harbour management. In an installation of such a remote sensing system in Haifa Port, consistent radially aligned spikes of brightness randomly distributed with respect to azimuth were identified. These streak noise patterns were found to be interfering with the common approach of oceanographic analysis. Harbour areas are regularly frequented with additional electromagnetic transmissions from other ship and land-based radars, which may serve as a source of such interference. A new approach is proposed for the filtering of such undesirable interference patterns from the X-band radar images. It was verified with comparison to in-situ measurements of a nearby wave buoy. Regardless of the actual source of the corresponding pseudo-wave energy, it was found to be crucial to apply such filtration in order to improve the performance of the standard oceanographic parameter retrieval algorithm. This results in better estimation of the mean sea state parameters towards lower values of the significant wave height. For the commercial WaMoSII system this enhancement was clearly apparent in the improvement of the built-in quality control criteria marks. The developed prepossessing procedure improves the robustness of the directional spectra estimation practically eliminating pseudo-wave energy components. It also extends the system’s capability to measure storm events earlier on, a fact that is of high importance for harbour operational decision making.
Development of Air Quality Boxes Based on Low-Cost Sensor Technology for Ambient Air Quality Monitoring
Authors: Gäbel Paul , Koller Christian , Hertig Elke
Published: May 2022

Analyses of the relationships between climate, air substances and health usually concentrate on urban environments because of increased urban temperatures, high levels of air pollution and the exposure of a large number of people compared to rural environments. Ongoing urbanization, demographic ageing and climate change lead to an increased vulnerability with respect to climate-related extremes and air pollution. However, systematic analyses of the specific local-scale characteristics of health-relevant atmospheric conditions and compositions in urban environments are still scarce because of the lack of high-resolution monitoring networks. In recent years, low-cost sensors (LCS) became available, which potentially provide the opportunity to monitor atmospheric conditions with a high spatial resolution and which allow monitoring directly at vulnerable people. In this study, we present the atmospheric exposure low-cost monitoring (AELCM) system for several air substances like ozone, nitrogen dioxide, carbon monoxide and particulate matter, as well as meteorological variables developed by our research group. The measurement equipment is calibrated using multiple linear regression and extensively tested based on a field evaluation approach at an urban background site using the high-quality measurement unit, the atmospheric exposure monitoring station (AEMS) for meteorology and air substances, of our research group. The field evaluation took place over a time span of 4 to 8 months. The electrochemical ozone sensors (SPEC DGS-O3: R2: 0.71–0.95, RMSE: 3.31–7.79 ppb) and particulate matter sensors (SPS30 PM1/PM2.5: R2: 0.96–0.97/0.90–0.94, RMSE: 0.77–1.07 µg/m3/1.27–1.96 µg/m3) showed the best performances at the urban background site, while the other sensors underperformed tremendously (SPEC DGS-NO2, SPEC DGS-CO, MQ131, MiCS-2714 and MiCS-4514). The results of our study show that meaningful local-scale measurements are possible with the former sensors deployed in an AELCM unit.
Designing an AI-Based Virtual Try-On Web Application
Authors: Marelli Davide , Bianco Simone , Ciocca Gianluigi
Published: May 2022

In the last few years, Augmented Reality, Virtual Reality, and Artificial Intelligence (AI) have been increasingly employed in different application domains. Among them, the retail market presents the opportunity to allow people to check the appearance of accessories, makeup, hairstyle, hair color, and clothes on themselves, exploiting virtual try-on applications. In this paper, we propose an eyewear virtual try-on experience based on a framework that leverages advanced deep learning-based computer vision techniques. The virtual try-on is performed on a 3D face reconstructed from a single input image. In designing our system, we started by studying the underlying architecture, components, and their interactions. Then, we assessed and compared existing face reconstruction approaches. To this end, we performed an extensive analysis and experiments for evaluating their design, complexity, geometry reconstruction errors, and reconstructed texture quality. The experiments allowed us to select the most suitable approach for our proposed try-on framework. Our system considers actual glasses and face sizes to provide a realistic fit estimation using a markerless approach. The user interacts with the system by using a web application optimized for desktop and mobile devices. Finally, we performed a usability study that showed an above-average score of our eyewear virtual try-on application.
Is it possible to refuse employment on the grounds of non-conformity of the applicant’s qualities to corporate values? Legal aspect
Authors:   ", Vasilyeva K.V. ,   S.Y. Witte Moscow University"
Published: May 2022

Even if your company complies with labor laws, there may be problems in the workforce that reduce the company's productivity and negatively affect its reputation. This is often due to the belief, character, behavior and other personal characteristics of one of the employees does not correspond to the values accepted in the company. Is it possible not to initially accept such candidates for work? What are the legal aspects of the problem?
Payments under an employment contract to an employee working remotely outside the Russian Federation
Authors:   Legal consulting ", Koreneva O. ,   GARANT"
Published: May 2022

In this material, the author will answer the following question: what is the procedure for taxation (personal income tax, insurance premiums) of payments under an employment contract in favor of an employee — a citizen of the Russian Federation, a non-resident of the Russian Federation working in a Russian organization under an employment contract remotely, being outside the Russian Federation (China)?
The features of legal regulation of personal data of remote workers
Authors:   Altai State University, Barnaul, Prasolova I.A. , Vasilenko Yu.E. ,   Altai State University, Barnaul, Mikhaylenko Yu.A. ,   Altai State University, Barnaul
Published: May 2022

To date, the Russian Federation has been formed as an information state, the priority task of which is to protect the interests of the individual, his rights and freedoms guaranteed by the Constitution of the Russian Federation. The widespread use of modern technologies, in particular all kinds of transfers of personal data, poses a real threat to the violation of not only constitutional guarantees for privacy, personal and family secrets, but also labor legislation. It should be recognized that electronic document management increases the opportunities for abuse of rights by workers and employers. In the article, the authors analyze some of the problems arising in the processing and protection of personal data of remote workers, law enforcement practice, and also propose ways of improving labor legislation in this field.
Problems of pension provision for working pensioners
Authors:   Perm State Research University, Mamatkazin I.R.
Published: May 2022

Working pensioners represent a special category of pension recipients. The legislation does not restrict their labor rights, equating them with other categories of employees, but in pension provision, there are significant restrictions on their rights in relation to these persons. These restrictions are primarily related to the payment of pensions “not in full”, when it comes to the non-application to working pensioners of provisions on the indexation of insurance pensions or the absence of their right to a social supplement to the pension. Very significant are the restrictions in the formation of their pension rights in the exercise of labor activity after the appointment of an insurance pension. These restrictions, each of which individually is not so significant, collectively represent a very serious factor that negatively affects the motivation of pensioners to continue working.
The factors of influence on use of available agricultural lands, spatial development of agricultural land use, its expansion or shrinking
Authors:   FGBNU FNC VNIIESH, Moscow, Alakoz V.V.
Published: May 2022

The existing resource potential of productive agricultural land is not used by one third, and the productivity of used agricultural land barely reaches 20-40% of the potential yield. Agriculture in many regions has ceased to be an essential part of rural economy, a source of jobs and income for rural residents. There is a steady tendency to shrink living space – bankruptcy of agricultural producers, depopulation of rural areas, crushing and disappearance of villages, degradation of engineering and social infrastructure. Life in many rural areas is supported by the pensions of the elderly and the salaries of state and municipal employees. Many rural areas of the Non-Black Earth Region, remote from large civilizational centers, are turning into territories of survival without any hope of revival. Instead of contemplative observation, it is necessary to make reasonable management decisions and mechanisms for their implementation, including support for those who need it instead of feeding people hiding in offshores the super profits received in Russia.
Technical characteristics of high-performance agricultural machinery in projects of on-farm land management
Authors:   State University of Land Management, Moscow, Volkov S.N. , Mamedova E.E. ,   State University of Land Management, Moscow
Published: May 2022

The effective functioning of high-performance agricultural machinery requires taking into account its technical characteristics when organizing the territory of agricultural organizations. The article discusses the issues arising during land management in agricultural organizations, identifies the features of the use of agricultural machinery, presents the technical characteristics of foreign and domestic harvesters in various natural zones of the Russian Federation, and formulates recommendations that must be taken into account when designing crop rotations and arranging their territory in projects of on-farm land management.
The main directions of land management work made for religious objects
Authors:   State University of Land Management, Moscow, Ivanov N.I. , Gaprindashvili R.T. ,   State University of Land Management, Moscow, Sorokina O.A. ,   State University of Land Management, Moscow, Krasnianskaya E.V. ,   State University of Land Management, Moscow, Poyan A. ,   State University of Land Management, Moscow, Kosinskiy V.V. ,   State University of Land Management, Moscow, Fedorinov A.V. ,   State University of Land Management, Moscow, Geraskin M.M. ,   State University of Land Management, Moscow, Svirezhev K.A. ,   State University of Land Management, Moscow
Published: May 2022

The article provides a brief history of the interaction of SULUP and religious organizations. The main works carried out by the SPO «Surveyor» SULUP on the church lands are presented in this paper. The work prospects of the student squad are considered here as well.
The shares of land and vegetation from the total land area in the subjects of Western Siberia
Authors:   Volga State Technological University, Yoshkar-Ola, Republic of Mari El, Mazurkin P.M.
Published: May 2022

A correlation matrix of six factors by the shares of land and vegetation from the total land area in 14 subjects of Western Siberia is considered in this paper. The group correspondence is assessed above 0.98 for the ecological coefficient X17, and above 0.99 for the other five parameters. The first place is taken by the parameter X14 – arable land. The coefficient of correlative variation is 0.8769 ("the more → the worse"). The factors X12 – farmland, X14 – arable land and X16 – human-modified lands are oriented to the factor «the less, the better», and X13 – forests, X15 – vegetation cover "grass + bushes + trees", and X17 – the ecological coefficient "the more the better". The greatest correlation coefficient of 0.9996 was obtained by the influence of X17 on X16. The interesting one is also X14 (arable land) – X12 (farmland).
Designing the structure and content of the land monitoring database (by example of Chelyabinsk region)
Authors:   GISS SUSU (NIU) — South Ural State University (NIU), Chelyabinsk, Rasskazova N.S..
Published: May 2022

The article is about the development of the structure and content of the land monitoring database (DB) on the example of Chelyabinsk region. First of all, the author performed an analysis of various database models and software environments, investigated advantages and disadvantages, and chosen the optimal DB model. After that, the author identified the territorial features of the region, which are taken into account in development the structure and content of the database.
The changes in legislation relating to dacha amnesty
Authors:   Meridian LLC, Dimitrovgrad, Ulyanovsk region, Garaeva E.V. , Tsapovskaya O.N. ,   Ulyanovsk GAU, Ulyanovsk, Russia, Ermoshkin Yu.V. ,   Ulyanovsk GAU, Ulyanovsk, Russia, Provalova E.V. ,   Ulyanovsk GAU, Ulyanovsk, Russia, Erofeev S.E. ,   Ulyanovsk GAU, Ulyanovsk, Russia
Published: May 2022

This article analyzes the changes in legislative acts concerning a simplified procedure for registration of ownership of individual residential houses, garden houses, residential buildings, as well as outbuildings erected on land plots provided to citizens for gardening, for individual housing construction or for personal subsidiary plots.
Zones with special conditions of use in the Russian Federation
Authors:   State University of Land Management, Moscow, Katalina L.A..
Published: May 2022

The article describes the basic concepts of zones with special conditions of use, security zones of real estate objects, and their types, features of establishment and principles of regulation.
Calculation of flows of autochtonic organic matter on the example of lake Nizhneye Barabinsky district Novosibirsk region
Authors:   Institute for Water and Environmental Problems SB RAS (IWEP SB RAS), Novosibirsk Branch, Yermolaeva Nadezhda Ivanovna , Zarubina Evgeniya Yurievna ,   Senior Researcher, Institute of Water and Environmental Problems SB RAS (IVEP SB RAS), Institute for Water and Environmental Problems SB RAS (IWEP SB RAS), Novosibirsk Branch, Fetter Gleb Vitalievich ,   Faculty of Natural Sciences of Novosibirsk State University, Institute for Water and Environmental Problems SB RAS (IWEP SB RAS), Novosibirsk Branch, Mitrofanova Elena Yurievna ,   nstitute for Water and Environmental Problems SB RAS (IWEP SB RAS), Vdovina Olga Nikolaevna ,   Institute for Water and Environmental Problems SB RAS (IWEP SB RAS)
Published: May 2022

Fluxes of matter, especially biogenic migration of elements, are the basis for the functioning of aquatic ecosystems. Currently, no models have been developed for assessing the processes of accumulation of organic matter in small lakes, whereas they are the main accumulators of organic matter of both allochthonous and autochthonous origin. In the proposed work, the calculation of the contribution of aquatic organisms to the total sedimentation flow in a typical small lake of the forest-steppe zone of the Baraba lowland is given in order to determine the sources of the formation of organic matter in the bottom sapropel. The assessment of the current state of the ecosystem of the water body according to the characteristics of the biocenosis: benthos, phytoplankton, zooplankton, higher aquatic vegetation. The production characteristics of various links of the hydrobiocenosis have been determined. Experiments with sedimentation traps have been set up. It is shown that Lake Nizhneye is characterized by all the signs of a eutrophic lakes: overproduction of primary production with an excess supply of organic matter in bottom sediments; desynchronization in the development of producers and consumers; suppression of the pasture chain and a shift in the flow of substances and energy into the detrital chain. Sapropel in Lake Nizhny has a macrophytic-planktonic genesis, which is typical for actively swamping aging lake ecosystems of the forest-steppe region. The share of autochthonous organic matter is 34%. More than half of the sedimentation flow comes from the catchment area. The accumulation rate of sapropel can fluctuate annually depending on weather conditions and the development of producers and averages 1.25 cm per year. The extraction of sapropel and the cleaning of the lake basin from the accumulated bottom sediments can be in the future to restore the fish productivity of the reservoir.
Estimation of Zagorsky carps genetic variability using microsatellite analysis
Authors:   branch for Freshwater Fishery of Federal State Budgetary Scientific Institution “Russian Federation Research Institute of Fishery and Oceanography”, Ivanekha Elena Victorovna , Duma Ludmila Nicolaevna ,   the branch for Freshwater Fishery of Federal State Budgetary Scientific Institution “Russian Federation Research Institute of Fishery and Oceanography”
Published: May 2022

Six microsatellite dinucleotide loci were used to study the genetic variability in three generations of Zagorsky carp. All investigated loci are polymorphic with number of alleles from 4 to 9 per locus. The part of heterozygotes at microsatellite alleles in this breeding group was high, on the average more than 87%. Genetic variability of Zagorsky carp last selective generations has been revealed to be kept high, but it stay lower than that of Moscow Scaly and Moscow Mirror carps (intrabreed types of Parsky breed). Sixth and seventh generations showed somewhat less genetic variability than fifth generation did, in this connection further control of its level is desirable. The loss of 2 alleles from two microsatellite loci, MFW1 and MFW9, was found at sampling of Zagorsky carp seventh generation; these alleles occurred in both preceding generations. 18% of Zagorsky carps had only one of two amplification products (additional) at MFW31 locus, whereas the other carp groups had both products or hadn’t additional product in rare samples. No specific alleles for genetic marking of this breeding group have been found at six microsatellite loci. Allele sizes at all these loci in Zagorsky carp group and in other examined carp groups lay in the same length ranges.
The effectiveness of using the synbiotic drug “ProStor” as additives in compound feed when growing carp fingerlings in pond conditions
Authors:   Saratov branch of FSBSI “VNIRO”, Russia, Maslyakov Viktor Petrovich , Legkodimova Zinaida Ivanovna ,   Saratov branch of FSBSI “VNIRO”, Russia, Silnikova Galina Vasilevna ,   Saratov branch of FSBSI “VNIRO”, Russia, Kiyashko Vladimir Valentinovich ,   Saratov branch of FSBSI “VNIRO”, Alexandrov Yan Vladimirovich ,   Saratov branch of FSBSI “VNIRO”, Russia
Published: May 2022

The stimulating effect of the synbiotic drug “ProStor” on the body weight gain of fish and their physiological state was previously considered in various scientific sources when growing various fish species in swimming pools, cages and experimental aquariums. With the intensification of pond fish cultivation with compacted carp plantings, the percentage of natural forage organisms in the food lump is minimized, and, accordingly, the main weight gain of fish is carried out by feeding with compound feeds. In such conditions, the importance of using probiotic supplements in carp feeding becomes relevant. For a more complete description of the stimulating effect of probiotics, studies were conducted on feeding carp fingerlings in pond conditions of the Saratov region using the synbiotic drug “ProStor”. As a result of the conducted studies, it was revealed that the fish productivity of the outgrowth pond, where young carp were fed mixed feed with the drug “ProStor”, was 20% higher than in the control pond. Higher fish productivity was accompanied by better indicators of carp fingerlings by their average weight, which was 29.6 g and 26.4 g, respectively, in the experimental and control outgrowth ponds. In addition, the use of the developed drug by the company “STC BIO” LLC allowed to reduce feed costs when growing carp fingerlings, which indicates an increasing factor on the quality of compound feed of the synbiotic drug used. On average, the economic efficiency of the use of “ProStor” additives allows you to get an additional profit from one hectare of pond area compared to the control up to 22.5 thousand rubles.
Features of cost accounting and calculation of the cost of production of honey-pollinating direction of beekeeping
Authors:   Stavropol State Agrarian University, Kostyukova E. I. , Manzhosova I. B. ,   Stavropol State Agrarian University, Frolov A. V. ,   Stavropol State Agrarian University
Published: May 2022

Beekeeping has a high value due to the commercial products obtained and the creation of opportunities for natural pollination of agricultural crops in order to increase their yield. Based on this, intensive farming territories have a great potential in the development of the industry. The article describes the features of calculating the products of honey-pollinating direction of beekeeping; the composition and structure of production costs, the procedure for calculating the actual cost of production of honey-pollinating direction of beekeeping are considered. The subject of the study is the system of cost accounting and calculation of the cost of production of honey-pollinating direction of beekeeping in the Stavropol Territory. The information base was the forms of specialized reporting of agricultural organizations of the Stavropol Territory. The scientific novelty of the research consists in the development of methods for calculating the cost of beekeeping products of an economy that has a honey-pollinating direction.
Implementation of a balanced scorecard in the inter-organizational management accounting system
Authors:   Federal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”, Khoruzhy L. I. , Katkov Yu. N. ,   Federal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”, Romanova A. A. ,   Federal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”
Published: May 2022

The article substantiates the application of a system of balanced indicators based on a cybernetic internal control system in order to ensure inter-organizational cooperation of agricultural formations. The widespread use of innovative technologies has led to the objective need to introduce new software solutions into the organization, including in relation to the system of economic security of inter-organizational cooperation. In order to promptly obtain the necessary data and make important management decisions, a mechanism is required that allows for the support of such decisions in a short time. Such a mechanism is a cybernetic system of internal control in combination with a balanced scorecard. The purpose of the study is to introduce a balanced scorecard into the inter-organizational management accounting system. Particular attention is paid to the issues related to the elements of the relationship between the cybernetic system of internal control and the system with
Management control in the accounting and analytical system of agro-formations
Authors:   Federal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”, Khoruzhy L. I. , Katkov Yu. N. ,   ederal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”, Titova V.A. ,   Federal State Budgetary Educational Institution of Higher Education “RGAU — MSHA named after K. A. Timiryazev”
Published: May 2022

The article is devoted to management control in the accounting and analytical system of enterprises of the agro-industrial complex. The issue of management control is debatable, both from the point of view of clarifying its theoretical component and from the point of view of the method of its formulation and implementation. The lack of managerial control in organizations leads to the irrational use of intellectual, organizational, information and financial resources, an unjustified increase in labor costs, an increase in the cost of products, a decrease in competitiveness, and negatively affects the economic safety of agricultural formation. Therefore, the authors of the article offered their own opinion on the management control system, in order to build managerial control in agricultural enterprises as efficiently as possible. On the basis of the analysis and current representations on management control, its author’s definition was proposed and the regulatory framework was disclosed. The stages of building a management control system in agro-formation are described. The place of management control in the structure of the agro-industrial complex enterprise is indicated, and its structure is presented. The registration and analytical register is developed for carrying out the express analysis of expenses of agroformation.
Antibiotic Susceptibility Profiles of Aeromonas hydrophila Isolates From Aquaculture Farms and Response to Potential Antibacterial Plant Extracts
Authors:   Research Institute for Aquaculture No.1, Dinh Bang, Tu Son, Bac Ninh, Viet Nam, DANG LUA T. , NGUYEN HANH T. , PHAM YEN T. , TRUONG HANH M.T.
Published: May 2022

Aeromonas spp., which inhabits freshwater and marine water bodies, can be responsible for the diseases and mortalities of many different cultured fishes. In this study, the antibiotic susceptibility profiles of 20 Aeromonas hydrophila strains isolated from diseased freshwater fish cultured in the Red River Delta, Vietnam were categorised as non-wild-type (non-WT) strains or were resistant to at least one antibiotic. Also, in-vitro antibacterial activities of extracts from two local plants against several antibiotic-resistant A. hydrophila strains were done to screen for potential bio-antibiotic materials. The antibiotic susceptibility results showed that 25 % of bacterial strains were resistant to 3–9 antibiotics, 35 % to 2 antibiotics, and 10 % to one antibiotic. Both plants, rose myrtle seed, Rhodomyrtus tomentosa Hassk, 1842, extract and fermented garlic, Allium sativum Linnaeus, 1753, supernatant, showed inhibitory activities against antibiotic-resistant A. hydrophila strains. Furthermore, the R. tomentosa extract and the fermented A. sativum supernatant exhibited significant antibacterial effects to several A. hydrophila strains, namely A. hydrophila CEDMA17.021, CEDMA17.002, CEDMA17.008, and CEDMA17.009 resistant to two or more antibiotics. This study demonstrated multiple resistant profiles of A. hydrophila strains to different antibiotics and the inhibitory activities of R. tomentosa extract and the fermented A. sativum supernatant against antibiotic-resistant A. hydrophila strains. Hence, this study indicates the potential use of bio-antibiotics derived from plants to manage Aeromonas-related infections.
PERAN KEPEMIMPINAN KEPALA SEKOLAH DALAM UPAYA MENGEMBANGKA PROFESIONALISME GURU
Authors: Indriyani Sri , Hasanah Enung
Published: May 2022

The principal is a strategic element strengthening the professional quality of reachers ini improve the quality of education in an institution that has a direct impact on learning. However, this is not supported by professional teachers, and teacher are still have standards that have been set even more so those in eastem areas that still have lack of professional education personnel with a very low number of teaching staff as well as the mismatch of the available aducation personnel with the subjects is still lacking. Therefore, the aim of this research is to examine the leadership roles of the principal in the effort develop teacher professionalism. This method uses literature review or litearture research, which is to study literature books that are in accordance with the teory discussed in the scope principal leadership and also analyzes scientific articles cited with using spinger link and google scholar. The results is showed that the role of leadership the principal by providing guidance, motivation and supervisioan, they are can improve professionalism of teachers in work which can have implication for learing process. Leadership principals in an effort to develop teachers professionalism can be done through, such as : 1) teacher attend training and seminars, 2) join to workshops or activities like KKG/MGMP/MGBK are used in designing or developing a learing curriculum and learing media.
MODEL DISCOVERY LEARNING DALAM PEMBELAJARAN MATEMATIKA TERHADAP KEMAMPUAN PEMAHAMAN KONSEP SISWA KELAS VII MTSS DARUSSALAM AMPING PARAK
Authors:   STKIP Pesisir Selatan, Sefrinal Sefrinal , Syafti Okviani , Arif Muhammad
Published: May 2022

This research is motivated by the monotonous teacher teaching method, which requires students to remember the material without asking to understand the concept of learning mathematics. So that mathematics learning has not achieved the expected results. To solve this problem, the Discovery Learning model (guided discovery) is a solution that will be tried. The goal is that there is a change in student learning attitudes and teacher teaching so that they will get good learning outcomes and achieve KKM. This research model uses a quantitative approach with experimental methods, with a random research design on the subject. The population in this study were students of class VII MTsS Darussalam Amping Parak for the 2020/2021 academic year which consisted of two classes. The sampling technique was carried out randomly, class VIIB as the experimental class and VIIA as the control class. The instrument used in this study was a reliable essay final test. The data analysis technique used is the one-party t test. Hypothesis testing using the one-party t-test, obtained t = 3.21 and t table = 1.67. Because tcount> ttable, this research hypothesis is accepted. So, it can be concluded that the mathematics learning outcomes of students using the Discovery Learning Model are better than the mathematics learning outcomes of students taught using conventional learning in class VII students of MTsS Darussalam Amping Parak for the 2020/2021 academic year
PENGARUH WORD OF THE DAY DAN WORDS GROUPING ACTIVITIES TERHADAP HASIL BELAJAR VOCABULARY SISWA KELAS VIII DI MTs.S BAHRUL ‘ULUM PESISIR SELATAN
Authors:   STKIP Pesisir Selatan, Saputra Bobi , Efendi Efendi , Ramadhani Ramadhani
Published: May 2022

This study aims to determine the effect of Words of The Day and words grouping activities on the Vocabulary learning outcomes of grade VIII students at MTs.S Bahrul 'Ulum Pesisir Selatan. The research was conducted in class VIII MTs.S Bahrul 'Ulum, Pesisir Selatan Regency. This type of research is a quasi-experimental class using experimental class and control class. The research subjects taken were students in class VIII MTs.S Bahrul 'Ulum, Pesisir Selatan Regency. Data collection techniques that will be carried out in this study are tests and documentation. Data collection using student learning outcomes tests is intended to get an overview of the learning outcomes of groups of students taught using Words of The Day and word rouping activities against groups of students taught using conventional learning methods. Documentation is used to obtain data about the list of names of students who are the research subjects. The results in this study indicate that (1) that the Vocabulary learning outcomes of students using the Words of The Day learning method and word rouping activities are better than the learning outcomes of students using conventional learning methods with the value sig. (2-tailed) 0.020 < α 0.05, (2) there are differences in learning outcomes. Before and after students' Vocabulary groups used the Words of The Day learning method and word rouping activities with the value sig. (2-tailed) 0.002 < α 0.05
TRANSFORMASI PEMBELAJARAN FISIKA DASAR DI MASA PANDEMI
Authors:   Universitas Riau, Syafi'i Muhammad
Published: May 2022

The covid-19 pandemic demands changes to the learning system. Changes in the learning system cause learning activities, media, assignments, and learning assessments to undergo adjustments to be carried out online. Fundamental physics is one of the courses in several study programs which must also be adjusted according to its implementation. Currently, many learning platforms are available. The purpose of this research is to examine the learning platforms that are often used for Fundamental Physics courses. This type of research is literature study research. The data obtained is secondary data from published articles. The results of this study indicate that the learning platforms that are most often used are Moodle, Edmodo, and Google Classroom. The platforms for virtual labor are macromedia and Phet simulation. Ease of use is the main basis for selecting the platform by educators, besides that the existence of discussion and conference services is an added values. As for virtual labor, Phet simulation is considered more practical because it can use existing simulations, it's just that not all the experimental forms that educators want can be available in Phet simulation
Formalized model of polarization of a biopolymer composite in an inhomogeneous temperature field
Authors: MATVEEV N. N. , LISITSYN V. I. , KAMALOVA N. S. , EVSIKOVA N. YU.
Published: May 2022

The article presents a formalized model built according to classical thermodynamics that describes the polarization mechanism in a layer of wood in an inhomogeneous temperature field. The model provides the basis for a computational experiment to determine the parameters of the kinetics of the wood microstructure based on the measurement data of the potential difference that occurs in a sample in a non-uniform temperature field.
Storing lubricants in polyethylene containers
Authors: RYBAKOV YU. N. , KOLOTILIN D. V. , DEDOV A. V. , KUNNAP R. I. , NAZAROV V. G.
Published: May 2022

Losses of oils during storage and transportation in containers based on soot-filled low-pressure polyethylene were investigated. The limitations of the standard method for determining the diffusion permeability of polymers for assessing the loss of oils from a container are established. The model for estimating the loss of oils during storage in a container was derived from the dependences of the reduction in the mass of oils on the conditional time, calculated as the square root of the time.
A VULNERABILIDADE E SUA IMPORTÂNCIA PARA O DIREITO DO CONSUMIDOR
Authors: Sampaio Fernandes Rios Helder
Published: May 2022

This work aims to demonstrate the importance of the principle of vulnerability for the consumer and evidences its participation as a guide for the objective of demonstrating consumer rights. which is seen through a historical journey from the beginning of society to the industrial revolution and the development of commerce. Part of the provision of vulnerable consumption that the consumer is considered the principle of vulnerability to maintain balanced consumption in the relationship with the supplier who is the holder of knowledge and power to control his product or service.
ANÁLISE DO INVESTIMENTO PÚBLICO NA EDUCAÇÃO BÁSICA E O DESEMPENHO DOS ALUNOS EM AVALIAÇÕES NACIONAIS NO ESTADO DE GOIÁS DURANTE O PERÍODO DE 2012 A 2019.
Authors: Marques Pereira Vanilda , Jorge de Oliveira Johnny
Published: May 2022

The article aimed to evaluate the public investments in basic education and the students' scores in national assessments in the state of Goiás from 2012 to 2019 and analyze the similarity between these factors in order to determine whether greater financial resources are associated with better school performance. The research methodology, characterized as exploratory, quantitative and bibliographic, was developed through correlation analysis, the data used to measure both the investment per state, per student, and the result of the scores in the evaluations were obtained from the National Treasury page, Siope and INEP. The results indicated that over the years the investment per student increased as well as their performance in the SAEB test, except in the years 2017 and 2019 that presented a drop in the investment per student, but the resource distributed to the State and the expenses in the area of education were disproportionate, because, a higher total amount was distributed to the State, but 70% of it was not spent, however, the performance of students in national assessments had progressively increased. Thus, we note that it is not a general rule to make a larger investment and obtain better results, the correlation was significant, but may be affected by other situations not analyzed in this study.