bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysing the variability of non-stationary extreme rainfall events amidst climate change in East Malaysia
Authors: Ng Jing Lin , Huang Yuk Feng , Yong Stephen Luo Sheng , Lee Jin Chai , Ahmed Ali Najah , Mirzaei Majid
Published: July 2024

Climate change is intensifying the occurrence of extreme rainfall events, drawing attention to the importance of understanding the return period concept within the realm of extreme weather studies. This study evaluates the stationarity of extreme rainfall series on both monthly and annual series across East Malaysia, employing the Augmented Dickey–Fuller, Phillips Perron, and Kwiatkowski–Phillips–Schmidt–Shin tests. To model these extreme rainfall series, various probability distributions were applied, followed by goodness-of-fit tests to determine their adequacy. The study identified the stationary and non-stationary return values at 25-, 50-, and 100-year return periods. Additionally, maps depicting the spatial distribution for non-stationary increment were generated. The results indicated that extreme monthly rainfall exhibited stationary characteristics, while extreme yearly rainfall displayed non-stationary characteristics. Among the tested probability distributions, the generalised extreme value distribution was found to be superior in representing the characteristics of the extreme rainfall. Furthermore, a significant finding is that the non-stationary rainfall exhibits higher return values than those of stationary rainfall across all return periods. The northeast coast of Sabah highlighted as the most affected area, with notably high return values for extreme rainfall.
Earthy/musty odour bioaccumulation in Plecoglossus altivelis grown in a land-based aquaculture fed by reclaimed secondary effluent in wastewater treatment plant
Authors: Pham Viet-Dung , Ogata Ei , Kato Hiroyuki
Published: July 2024

Reclaimed wastewater (RWW) has been used globally for centuries, though its application in aquaculture is less extensive. Limited study has addressed impacts of RWW-derived volatile odour compounds (VOCs), such as 2,4,6-trichloroanisole (TCA), 2-methylisoborneol (MIB), and geosmin (GSM), on fish quality. This study aims to (1) assess the feasibility of reusing secondary effluent from a municipal wastewater treatment plant (WWTP) for Plecoglossus altivelis aquaculture in a land-based flow-through system and (2) evaluate the sensory effects of selected VOCs on fish quality. Results showed that increased temperature and ammonia levels in summer RWW negatively affected fish growth, while autumn RWW did not. Heavy metals in fish did not cause health issues. TCA, MIB, and GSM concentrations in fish tissues were 4.7–5.7, 0.3–40.5, and 1.1–1.9 mg kg−1, respectively. TCA emerged as the most concerning odorant, with higher relative odour intensity than MIB and GSM in RWW-cultured fish, regardless of seasonal change. This study is the first to report on a self-constructed aquaculture system using RWW at a WWTP, recommending effective VOC and ammonia removal for sustainable RWW use in aquaculture. Additionally, the study highlighted TCA's impact as an anthropogenic indicator in aquatic environments amid increasing WWTP prevalence in developed cities.
KAJIAN KESUBURAN DAN KESESUAIAN LAHAN BERBASIS KOMODITAS DI KECAMATAN TUGU DAN KARANGAN KABUPATEN TRENGGALEK
Authors: Arifin Syamsul , Samudra Ferdianto Budi , Utami Kartika Budi , Putra Aditya Nugraha , Setiawan Adi , Riza Sativandi , Andhika Yosi , Maulidiyah Nurul
Published: July 2024

Drought is a major challenge in developing the integrated farming system (IFS) in Trenggalek Regency, making it one of the factors contributing to the construction of the Tugu Dam. Additionally, in developing the IFS area, it is necessary to assess soil fertility and land suitability evaluation for food and livestock feed commodities. The research was conducted in Tugu and Karangan Sub-Districts, Trenggalek Regency by conducting spatial analysis and soil survey at locations potentially affected by dam construction and soil samples analysis at the laboratory. The results of this study found that the level of soil fertility at the research site was included in the low to very low class with characteristics of acidic pH, very low C-organic, very low total N and low base saturation. While the results of the actual land suitability evaluation of rice, maize, and elephant grass showed the land suitability class S3 with limiting factors of C-organic, pH, total N, P2O5, and base saturation.
TINGKAT PENCEMARAN LOGAM Cd, Fe, Cr DAN Cu AIR SUMUR GALI DI Eks-TPA TALANG GULO KOTA JAMBI
Authors: Gusri Lailal , Yanova Shally , Gayatri Indah
Published: July 2024

Former solid waste disposal at Talang Gulo TPA Jambi City implements a waste management system using a controlled landfill. Leachate and rainwater absorb into the soil and accumulate to become polluted groundwater. Furthermore, the polluted water flows into the dug well water and can reduce the quality of the dug well water. The aim of this study is to determine the heavy metal pollution index of residents' dug well water and the influence of the distance between the ex-TPA and dug well water. This research method is purposive sampling based on the distance of heavy metal sample points, namely 70 m, 230 m and 300 m. Sample analysis used an Atomic Absorption Spectrophometer (AAS) in the laboratory. The results were classed and indexed (C/P), the groundwater was very lightly contaminated with Cd (<0.1), heavily contaminated with Fe (0.51-0.75), very lightly contaminated with Cr (<0.1), and moderately contaminated with Cu (0.26-0.50). Based on the R value of the four metals, it shows that there was a very high influence between the distance between the well water sample and the former solid waste disposal leachate product.
Integrating Palliative Medicine into Medical Education: Creating a More Compassionate Generation of Physicians
Authors: Mackey Regina M. , Eick Macaila , Jacobsen Sara , Satiago Abraham Labrada , Lapid Maria I.
Published: July 2024

How should Palliative Medicine competencies be taught to medical students? In the United States and other countries, there is a consensus that teaching Palliative Medicine competencies to medical students is essential. Health agencies have also identified teaching Palliative Medicine competencies as crucial. According to Sanchez-Reilly and Ross, medical students reported that they feel better prepared to care for the elderly, patients with severe illness, and dying patients after completing formal training. The authors hypothesized that a one-week rotation with Palliative Medicine during the Medicine Clerkship would improve the medical students’ skills to care for these populations of patients. The one-week inpatient rotation was designed to equip all fifty medical students at Mayo Medical School with a knowledge base of Palliative Care, communication skills, care for elderly frail and dying patients, and basic pain management for patients with severe illness. Each of the fifty students rotated with a Palliative Care consulting team with patient interaction, lectures, online teaching, and interdisciplinary team activities. Hands-on learning proved more effective than using just the classroom teaching classical model, with 70% of students responding positively to the hands-on approach. Learning how to apply Palliative Care skills while visiting patients with complex diseases, showed to be better received as an education module. Out of the fifty medical students surveyed, thirty-five responded (70%), and all responses were positive. This method of teaching could be expanded to teach other advanced hospice and palliative care skills.
Technical Requirements, Design, and Automation Process for a Statewide Registry-Based Tailored Text Messaging System: The Heart Health Messages Program (Preprint)
Authors: Ogunsanmi Deborah Oluwaseun , Chambers Jerica J. , Pakker Avinash R. , Kompalli Anusha , Kabir Umar , Surbhi Satya , Gatwood Justin D. , Mahmood Asos , Bailey James E.
Published: July 2024

BACKGROUND

Tailored text messaging is a low-cost mobile health intervention approach shown to effectively improve self-care behaviors and clinical outcomes for patients with chronic cardiometabolic conditions. Given the ubiquitous nature of mobile phones, text messages have the potential to reach a large audience. However, automating and disseminating tailored text messages to large populations at low cost presents major logistical challenges that serve as barriers to implementation.

OBJECTIVE

This study describes an innovative approach for automating and disseminating personalized and tailored text messages to large populations at risk of cardiovascular events at a low cost using a registry-based tailored text messaging system known as the Heart Health Messages (HHM) program. We discuss the technical requirements, architectural design, automation process, and challenges associated with program implementation.

METHODS

Patients at high risk of cardiovascular diseases were identified using a statewide population health registry known as the Tennessee Population Data Network (TN-POPnet). Tailored invitation messages and enrollment surveys were sent to eligible patients via Twilio. Upon completion of the consent and enrollment forms, participants receive tailored text messages from a library of generic messages based on participant-selected frequency of message delivery (daily or every other day). Additionally, participants receive monthly text-based check-in survey messages designed to assess intervention adherence and improvement in self-care. Participants are also sent quarterly follow-up surveys to update enrollment information and preferences. All enrolled participants receive tailored text messages for a 12-month intervention period.

RESULTS

A total of 18,914 patients from two major health systems met the inclusion criteria and were eligible for the HHM program. Three phases of HHM 1.0 have been implemented so far, reaching 225 eligible patients in phase 1, 5,228 patients in phase 2, and 13,461 patients in phase 3, with enrollment of approximately 2%, 3%, and 3%, respectively, in each phase using recruitment through text message invitation alone. Efforts are underway to implement strategies in collaboration with the health systems to enhance the HHM program rollout and patient participation. The estimated cost of sending a tailored text message per patient per year via Twilio ranges from $1.70 to $3.42.

CONCLUSIONS

The HHM program is a low-cost tailored text messaging intervention set for broader dissemination and potentials for replication. The program has the capacity to improve outcomes for people with chronic medical conditions.

CLINICALTRIAL

N/A
The effect of non‐contact electro capacitive cancer therapy on DMBA‐induced rat breast tumor angiogenesis
Authors: Palupi Endah Sri , Retnoaji Bambang , Astuti Pudji , Alamsyah Firman , Taruno Warsito Purwo , Pratiwi Rarastoeti
Published: July 2024

Alternating Current‐Electric Field (AC‐EF) generated by non‐contact Electro Capacitive Cancer Therapy (ECCT) can inhibit breast tumor growth. However, its effect on breast tumor angiogenesis remains unclear. Since angiogenesis is involved in normal physiology and tumors, it is crucial to investigate the effect of ECCT on normal and breast tumor angiogenesis. Samples consisting of rat breast normal tissue and breast tumors were obtained from the biobank, with tumors induced by 7,12‐dimethylbenz (α) anthracene (DMBA) at 20 mg/kg BW 10 times over five weeks. Meanwhile, ECCT exposure of 150 kHz and 18 Vpp was conducted for 21 days at 10 hours/day. The qPCR method was used for gene expression analysis, while immunohistochemistry used antibody anti‐Vegfr2 that was used to detect Vegfr2 protein expression. Data were analyzed using one‐way ANOVA and t‐tests performed with GraphPad Prism ver.9.5.1 software. The results revealed no impact of ECCT exposure on normal breast tissue angiogenesis. Interestingly, there was a significant increase in the number of blood vessels following the upregulation of Vascular Endothelial Growth Factor Receptor‐2 (Vegfr2) as opposed to its primary signal, Vascular Endothelial Growth Factor‐A (Vegfa). Furthermore, gene expression of Hypoxia Inducible Factor‐1α (Hif1α) and Specificity Protein‐1 (Sp1) was similar to that of the control group, suggesting that Vegfr2‐dependent angiogenesis regulates ECCT‐treated breast tumor angiogenesis.
Frailty, Multimorbidity, and Polypharmacy
Authors: Mayne Kaitlin J. , Sardell Rebecca J. , Staplin Natalie , Judge Parminder K. , Zhu Doreen , Sammons Emily , Cherney David Z.I. , Cheung Alfred K. , Maggioni Aldo P. , Nangaku Masaomi , Rossello Xavier , Tuttle Katherine R. , Ihara Katsuhito , Iwata Tomoko , Wanner Christoph , Emberson Jonathan , Preiss David , Landray Martin J. , Baigent Colin , Haynes Richard , Herrington William G. ,   on behalf of the EMPA-KIDNEY Collaborative Group
Published: July 2024

Key Points

Frailty, multimorbidity, and polypharmacy overlap and are associated with higher risk of adverse health outcomes in CKD.

Empagliflozin was safe, well tolerated, and effectively reduced cardiorenal and hospitalization risk irrespective of these characteristics.

Absolute benefits appeared greater in the most frail participants in this post hoc analysis of EMPA-KIDNEY.

Background

Sodium-glucose cotransporter-2 inhibitors are recommended treatment for adults with CKD, but uncertainty exists regarding their use in patients with frailty and/or multimorbidity, among whom polypharmacy is common. We derived a multivariable logistic regression model to predict hospitalization (reflecting frailty) and assessed empagliflozin's risk–benefit profile in a post hoc analysis of the double-blind, placebo-controlled EMPA-KIDNEY trial.

Methods

The EMPA-KIDNEY trial randomized 6609 patients with CKD (eGFR ≥20 to <45 ml/min per 1.73 m2, or ≥45 to <90 ml/min per 1.73 m2 with urinary albumin-to-creatinine ratio ≥200 mg/g) to receive either empagliflozin 10 mg daily or matching placebo and followed them for 2 years (median). Additional characteristics analyzed in subgroups were multimorbidity, polypharmacy, and health-related quality of life at baseline. Cox regression analyses were performed with subgroups defined by approximate thirds of each variable.

Results

The strongest predictors of hospitalization were N-terminal prohormone of brain natriuretic peptide, poor mobility, and diabetes and then eGFR and other comorbidities. Empagliflozin was generally well tolerated independent of predicted risk of hospitalization. In relative terms, allocation to empagliflozin reduced the risk of the primary outcome of kidney disease progression or cardiovascular death by 28% (hazard ratio, 0.72; 95% confidence interval, 0.64 to 0.82) and all-cause hospitalization by 14% (hazard ratio, 0.86; 95% confidence interval, 0.78 to 0.95), with broadly consistent effects across subgroups of predicted risk of hospitalization, multimorbidity, polypharmacy, or health-related quality of life. In absolute terms, the estimated benefits of empagliflozin were greater in those at highest predicted risk of hospitalization (reflecting frailty) and outweighed potential serious harms.

Conclusions

These findings support the use of sodium-glucose cotransporter-2 inhibitors in CKD, irrespective of frailty, multimorbidity, or polypharmacy.

Clinical Trial registration number:

NCT03594110.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2024_09_23_CJASNSeptember19992.mp3
Automatic Medicine Reminder for Elder People Using Real Time Clock Module
Authors: Narendra Mr. G.
Published: July 2024

Abstract: As individuals age, their cognitive abilities diminish, leading to increased instances of forgetfulness, particularly in adhering to medication schedules. This poses significant health risks, including improper dosages or medication errors among the elderly. To address this issue, this study proposes an enhanced automatic medicine reminder system utilizing an RTC module integrated with an ESP32 microcontroller to facilitate precise medication timing and consistency. Furthermore, the inclusionof a GSM module enables caretakers to remotely monitor patients' adherence by receiving realtime notifications on their smartphones. This enhanced system offers a proactive approach to medication management, enhancing patient safety and caregiver oversight in geriatric healthcare settings.
Training on Making Sunscreen Cream from Tapak Dara Leaf Extract in Banjarsari Bojonegoro Village
Authors: Akhmad Al-Bari  , Titi Agni Hutahaen  , Atika Nirmala
Published: July 2024

Background: The use of natural ingredients, especially family medicinal plants (TOGA), for treatment has not received much attention from the public. The tapak dara plant has benefits, including being antihyperglycemic, antidiabetic, and antibacterial, an agent for reducing oxidative stress, and a sunscreen effect that can protect the skin from ultraviolet rays. This service activity aims to provide a new understanding to the public about the benefits of the TOGA plant, especially periwinkle so that they can preserve and process it as sunscreen cream. Method: This training uses a technique of presenting material through training videos and explanatory slides. This training activity was conducted in Banjarsari Village using video material and PowerPoint slides. This training in making sunscreen cream involved 50 PKK cadres and was carried out for two months. Results: During the two-way discussion, participants' enthusiasm was seen in the questions asked regarding the technicalities of making the cream and the benefits of the tapak dara plant, showing the public's great interest in using herbal cosmetics from the TOGA plant. Conclusion: Training on making sunscreen cream from tapak dara leaf extract in Banjarsari Village is an effort to inform the community about the process of making cream from the TOGA plant with the result of community enthusiasm for holding similar activities.
Pendampingan Pelatihan IT Essential Cisco Networking Guna Meningkatkan Daya Saing Lulusan SMK N 3 Yogyakarta
Authors: Kusumaningrum Anggaraini , Wintolo Hero , Dewi Retnowati Nurcahyani , Setiawan Honggowibowo Anton , Pujiastuti Asih
Published: July 2024

Pendahuluan: Kemahiran dan pemahaman di bidang teknologi khususnya jaringan komputer merupakan salah satu tujuan yang dapat dikuasai siswa setelah lulus SMK. Selama proses pembelajaran, kesenjangan pemahaman antara teori dan praktik mengakibatkan siswa kurang menguasai teori dan praktek. Kurangnya media praktek untuk pengenalan hardware, software dan network device  menjadi kendala dalam proses pembelajaran teori dan praktek di SMK N 3 Yogyakarta. Studi ini bertujuan untuk menambah kemampuan dan keahlian para siswa agar kompetensinya meningkat. Metode: Analisis SWOT. Hasil: Sebanyak 36  siswa SMKN 3 Yogyakarta berhasil menyelesaikan pelatihan dan lulus. Kesimpulan: Sebanyak 36 siswa SMKN 3 Yogyakarta berhasil menyelesaikan pelatihan, lulus, serta mendapatkan sertifikat dengan rata-rata nilai kumulatif hasil ujian sertifikasi IT Essential Cisco Networking adalah 84,21, nilai minimal 76,38, dan nilai maksimal 94,55.
Impacto del clima organizacional sobre la rotación de los trabajadores: revisión 2013-2023
Authors: Terrones Mayta Ronald Emiliano , Haro Zea Karla Liliana
Published: July 2024

El propósito de este artículo es llevar a cabo una revisión de literatura relativa al impacto del CO (Clima Organizacional) sobre la RL (Rotación Laboral). La metodología para esta investigación es la revisión sistemática de literatura. La estrategia de búsqueda se realizó mediante la declaración PRISMA 2020, con una ventana de observación de los últimos 10 años (2013 –2023), utilizando las bases de datos Scopus, Science Direct, Emerald y EBSCO. Un ambiente laboral saludable y productivo se fomenta con un CO positivo, el cual es el resultado del constante esfuerzo de la empresa por crear un entorno de trabajo agradable y saludable; esto parte de alinear el CO a la filosofía empresarial con acciones que promuevan identidad y el trabajo en equipo. Con el fin de alcanzar la competitividad, las organizaciones deben enfocarse en mejorar el CO y disminuir la RL, haciendo un diagnóstico de necesidades organizacionales y poder tomar las decisiones acertadas.
LAW ENFORCEMENT BPOM BANDA ACEH AGAINST CRIMINAL ACTS. FOOD PRODUCTION USES BORAX AND FORMALIN
Authors: Yuhermansyah Edi , Akbar Hajarul , Alya Cut
Published: July 2024

The need for food production is inseparable from the efforts of consumers who want food to last longer, thus triggering food producers to compete to make the food according to the wishes of consumers in a way that is not justified by laws and regulations, but this method will cause various diseases, even death. BPOM has a basis for law enforcement against criminal acts of food production according to the provisions of Article 6 Paragraph (1) and Article 7 Paragraph (2) of Law Number 8 of 1981 concerning criminal procedural law. The questions in this thesis are how is the law enforcement of food production crimes carried out by BPOM Banda Aceh, and what are the inhibiting and supporting factors for food production crimes. This study uses field research and uses qualitative research methods with an empirical juridical approach and applies two forms of data collection methods, namely interviews and documents. The results of the study showed that law enforcement was carried out by BPOM Banda Aceh, namely based on evidence from testing results, the process was submitting evidence to the prosecutor's office, destroying evidence, imposing administrative sanctions, BPOM obstacle factor was the lack of investigators, investigators did not have much authority in detention, requests from consumers, food producers do it repeatedly, while the supporting factors for BPOM investigators are having a laboratory car, cooperative actors. From the explanation above, the authors can conclude that law enforcement by BPOM investigators is still not optimal and still has obstacles.
An Overview of Synthesis and Applications of Chalcone Derivatives
Authors: Ahmed Haya ,   Department of Chemistry, College of Science, Al-Nahrain University,Jadiriya, Baghdad,Iraq, A. Ahmed Ahmed , Al-Ani Ahmed , Jebali Jamel , M. Redwan Amamer ,   Department of Chemistry, College of Science, Al-Nahrain University,Jadiriya, Baghdad,Iraq,   Department of Chemistry, College of Science, Al-Nahrain University,Jadiriya, Baghdad,Iraq,   Higher Institute of Biotechnology of Monastir University of Monastir, Monastir, Tunisia,   Department of Chemistry, Faculty of Science, Bani Waleed University, Bani Waleed, Libya
Published: July 2024

Chalcone and its derivatives have attracted great attention because of a wide range of biological activities such as, antimicrobial, anticancer, antioxidant, anti-anthelmintic, anti-amoebicidal, antiulcer, antiviral, insecticidal and immunosuppressive. The presence of functional groups and conjugation within the structure make it a good candidate for these applications. This review highlighted the synthesis of chalcone derivatives which were described by researchers and studied their biological activity.
A modified Delphi study for development of an adolescent medicine curriculum for emergency medicine residents
Authors: Williams Eileen S , Bretz Lauren A , Fisher Kathryn M
Published: July 2024

Purpose: More than 1,500,000 adolescents in the United States report using emergency services for the majority of their medical needs. Although the American Council for Graduate Medical Education offers some guidance on the inclusion of pediatric topics in an emergency medicine (EM) residency curriculum, it does not specifically address adolescent-related competencies. We aimed to develop a consensus on which adolescent health topics are most important to cover in a didactic curriculum for EM residents.Methods: Physicians from multiple specialties, such as EM, pediatric EM, and adolescent medicine, were invited as panelists in a modified Delphi process. In round 1, the panelists were asked to determine which competencies in adolescent medicine are most important for a graduating EM resident to master. In round 2, they were asked to specify the competencies that should be included in an EM residency didactic curriculum. In round 3, they prioritized the most critical competencies for curriculum inclusion.Results: Consensus was reached on a total of 26 topics that were found crucial to be included in a didactic curriculum for EM residents. Of these, the panel prioritized the following: (1) “manage a patient presenting after reported sexual assault,” (2) “accurately diagnose ovarian torsion,” and (3) “manage a patient presenting for symptoms of sexually transmitted infection.” Conclusion: The modified Delphi process yielded recommendations to guide the development of an adolescent medicine curriculum for EM residents. Sexual and reproductive healthcare issues were identified as the most important topics.
Prospects of Small-Scale Rice Processing Enterprise among Beneficiaries of Microfinance Loan in Nigeria’s Jigawa State
Authors: Sadiq Mohammed , Salihu Musa , Sani Bashir
Published: July 2024

The present study empirically determined the prospects of the rice value chain of paddy processors in Jigawa State of Nigeria. Despite the role of small-scale paddy rice processors as the main engine of growth of upstream rice value chain, and the growth and development of the rural economy in the study area, literature is undaunted with paucity of empirical information on the prospects of rice processing value chain in the study area. The study utilised cross-sectional data elicited through a well-structured questionnaire from a total of 200 processors (133 parboilers and 67 millers) selected through a multi-stage sampling technique. An easy cost-route approach was used for data collection during the 2022 processing period and the collected data were analysed using both descriptive and inferential statistics. Based on the empirical evidence, it is established that the rice processing potential has not been fully exploited in the study areas. In addition, it is evident that the rice processing enterprise is not only viable and profitable; it features good prospects in the supply value chain of rice in the study areas. However, to maintain the prospects in the supply value chain, the target actors must adopt a defensive mechanism, as inferred by the SPACE matrix.
Assessment of the size of the danger zone caused by an accident during transportation of a dangerous chemical substance
Authors: Ivkovic Aleksandar , Ilic Srecko , Radovanovic Radovan , Mladenovic Nevena
Published: July 2024

Air pollution is the central topic of all discussions related to environmental protection. Modelling the spread of pollution is one of the methods used to predict the spread paths and levels of pollution and to act in order to combat this problem. The paper presents modelling of dispersion of ammonia through the air using a software tool ALOHA (Areal Locations of Hazardous Atmospheres) based on the Gaussian model of particle dispersion. Modelling in the work is based on data related to the accident that occurred in December 2022 in the vicinity of the city of Pirot, Serbia, as well as on real meteorological data that were collected during the time of the accident and the spread of pollution. As a result of modelling, zones with increased ammonia concentration are obtained. The zone areas will depend on the ammonia concentration at the source and meteorological conditions during the period of the leakage. The aim of the paper is to point out the need to introduce modelling into the operational centres of the local police or military units in charge of emergency situations, as well as additional safety protocols when transporting dangerous goods.
Breech presentation - maternal and neonatal outcomes and obstetric challenges
Authors: Todic Ivana , Plesinac Snezana , Stefanovic Tomislav
Published: July 2024

Introduction/Objective. Breech presentation occurs in 3?4% singleton pregnancies at term and its management is still a controversial in obstetric practice. The aim of this study was to determine the factors that indicate breech delivery management and to compare maternal and neonatal outcomes in vaginal breech delivery, planned Cesarean section (C-section) and emergency C-section at the Hospital for Gynecology and Obstetrics of the Zemun Clinical Hospital Centre. Methods. This was a retrospective study conducted from 2015 to 2019. Depending on the mode of delivery, patients were divided in three group. In this study, we have analyzed maternal risk factors and postpartum complications, delivery details and neonatal characteristics and outcomes. Results. The study included 176 women with singleton fetus in breech presentation. The incidence of breech deliveries was 2.12%. Most common way of delivery was vaginal with 47.72%. In all three groups, the majority of women were primiparous, at term, mostly without chronical and gestational diseases. Vaginal delivery was stimulated with oxytocin in 91.67%, and as a help for delivery various maneuvers were used. Maternal mortality and short-term complications during hospitalization period were reported in none of the groups. No significant difference in newborns birth weight between the groups was observed. The highest rate of birth injuries was in newborns from emergency C-section ? 10%. Conclusion. The results of our study have shown that vaginal delivery could be a very safe option for both mother and newborn.
Assessment of the socio-emotional state of persons with presbyacusia using hearing amplification
Authors: Maletic-Sekulic Ivana , Bunijevac Mila , Dragutinovic Ninoslava , Simikic Vesna
Published: July 2024

Introduction/Objective. Presbycusis or senile hearing loss is a physiological phenomenon that manifests as a gradual effect of hearing loss in adults. The aim of this work is to examine the socio-emotional state of elderly people with hearing loss. Methods. The research was conducted at the Department of Audiology and Vestibulology of the Zemun Clinical Hospital Center. A subjective assessment was conducted using the Hearing Handicap Inventory for the Elderly ? HHIE scale. This questionnaire is designed to assess the emotional and social functioning of people with presbycusis and to monitor the effect of auditory rehabilitation. Basic data were obtained through audiological diagnostics, questionnaires and interviews with respondents. Results. 120 subjects participated in this research, 60 subjects with senile hearing loss using auditory amplification and 60 subjects with senile hearing loss without hearing amplification. In subjects with auditory amplification, there is no statistically significant difference in the results of the HHIE at the beginning of the study and after one year (t = 1.07, df = 59, p = 0.28), but a statistically significant difference is observed in the HHIE-S score (t = 3.0, df = 59, p = 0.004). In 17 subjects who did not have a hearing aid at the beginning of the research, during the research, for a period of one year, auditory amplification was carried out and a good correlation between the HHIE and the subscales on the HHIE test/retest was established. Conclusion. Hearing amplification often does not fulfill its goal in individuals ? to improve listening and speech intelligibility, which may be a consequence of untimely amplification.
Oral Insulin Delay of Stage 3 Type 1 Diabetes Revisited in HLA DR4-DQ8 Participants in the TrialNet Oral Insulin Prevention Trial (TN07)
Authors: Zhao Lue Ping , Papadopoulos George K. , Skyler Jay S. , Parikh Hemang M. , Kwok William W. , Bondinas George P. , Moustakas Antonis K. , Wang Ruihan , Pyo Chul-Woo , Nelson Wyatt C. , Geraghty Daniel E. , Lernmark Åke
Published: July 2024

OBJECTIVE

To explore if oral insulin could delay onset of stage 3 type 1 diabetes (T1D) among patients with stage 1/2 who carry HLA DR4-DQ8 and/or have elevated levels of IA-2 autoantibodies (IA-2As).

RESEARCH AND METHODS

Next-generation targeted sequencing technology was used to genotype eight HLA class II genes (DQA1, DQB1, DRB1, DRB3, DRB4, DRB5, DPA1, and DPB1) in 546 participants in the TrialNet oral insulin preventative trial (TN07). Baseline levels of autoantibodies against insulin (IAA), GAD65 (GADA), and IA-2A were determined prior to treatment assignment. Available clinical and demographic covariables from TN07 were used in this post hoc analysis with the Cox regression model to quantify the preventive efficacy of oral insulin.

RESULTS

Oral insulin reduced the frequency of T1D onset among participants with elevated IA-2A levels (HR 0.62; P = 0.012) but had no preventive effect among those with low IA-2A levels (HR 1.03; P = 0.91). High IA-2A levels were positively associated with the HLA DR4-DQ8 haplotype (OR 1.63; P = 6.37 × 10−6) and negatively associated with the HLA DR7–containing DRB1*07:01-DRB4*01:01-DQA1*02:01-DQB1*02:02 extended haplotype (OR 0.49; P = 0.037). Among DR4-DQ8 carriers, oral insulin delayed the progression toward stage 3 T1D onset (HR 0.59; P = 0.027), especially if participants also had high IA-2A level (HR 0.50; P = 0.028).

CONCLUSIONS

These results suggest the presence of a T1D endotype characterized by HLA DR4-DQ8 and/or elevated IA-2A levels; for those patients with stage 1/2 disease with such an endotype, oral insulin delays the clinical T1D onset.
Personalets betydning når ekskludering skjer i barnehagens lekefellesskap
Authors: Iversen Lisbeth
Published: July 2024

Målet med artikkelen er økt innsikt i personalets handlinger og personalets betydning for barnehagens lekefellesskap i situasjoner der barn blir ekskludert. Datamaterialet er basert på kvalitativ forsking, med observasjoner i to barnehager med barn i alderen 3–6 år. Analysen viser at personalets første tilnærming til lekefellesskapet hvor ekskluderingen skjedde, kunne systematiseres i fire ulike tilnærminger: undersøkende, avvisende, innlemmende og korrigerende. Tilnærmingene så ut til å bety mye for videre utvikling av situasjonen, samt for relasjonene, tilhørigheten og handlingsrommet personalet og barna fikk videre. Studien bidrar til å synliggjøre hvor betydningsfulle personalets handlinger kan være for at barn skal bli ivaretatt når det oppstår ekskluderingssituasjoner, samt hvor komplekse slike situasjoner kan være.
English abstract
The Staff’s Influence when Exclusion Occurs in the Kindergarten’s Play Community
The aim of this article is to provide new knowledge about the actions of kindergarten staff. The article focuses particularly on situations where children are being excluded. The data material is based on qualitative research, with observations drawn from two kindergartens with children aged 3–6 years. The analysis shows that the staff’s first approach to the play community where an exclusion occurs could be systematized into four different approaches, namely, an explorative approach, a rejective approach, an incorporative approach, and a corrective approach. These approaches seem to mean much for the further development of the situation. This study also shows that the staff’s approach in an exclusion situation decides what space is used for professional agency, which may be significant with regard to how the process develops and what the result of the intervention will be.
Haemato-biochemical Alteration in Bacteria Associated Respiratory Tract Infection in Dog
Authors: Sarkar Bratati Deb , Barman Ditul , Kumar Nath Mrinal , Ghosh Tanay , Hazorika Mousumi , Kachari Jodumoni , Srikanth Sreeramdas
Published: July 2024

The research was undertaken during October, 2022 to June, 2023 to study the changes in haemato-biochemical values of the dogs suffered from respiratory tract infection due to bacteria. Blood samples were collected from healthy control group (Group A) and each dog of different treatment groups (Group B, Group C and Group D) on the 0th day (pre-treatment) and the 10th day (post-treatment) in K3-EDTA vacutainer tubes as well as clot activator-coated vacutainer tubes for haemato-biochemical estimation. In the result of haemato-biochemical study the highly significant difference (**p<0.01) was found in total leucocyte count, absolute neutrophil count and C-reactive protein. Statistically no significant difference (p>0.05) was observed in total erythrocyte count, haemoglobin, absolute eosinophil count, absolute lymphocyte count and albumin. In case of total protein a highly significant difference (**p<0.01) was observed between Group A and Group B on day 0 and on day 10. A highly significant difference was also observed between (**p<0.01) Group B and Group C; Group B and Group D on day 0 and day 10. On the other hand no significant difference (p>0.05) was observed within treatment groups. In case of globulin, statistically no significant difference (p>0.05) was obtained between the Group A and all the treatment groups on day 0 and day 10. No significant difference (p>0.05) was observed within treatment groups. However, a significant difference (**p<0.01) was found between Group B and Group C; Group B and Group D on 0th day and on the 10th day.
The Effect of Using Edugame Wordwall on Students' Mathematical Representation Ability
Authors: Salsabila Alna , Tsurayya Ayu
Published: July 2024

The difficulty students face in comprehending problems presented through diagrams and mathematical models, coupled with the monotony experienced during mathematics lessons, has resulted in low mathematical representation skills among students. While studies indicate that Wordwall can enhance student engagement, the specific factors influencing this engagement when utilizing Wordwall remain under-explored. This study aims to assess the impact of Wordwall media on students' mathematical representation abilities and determine the extent of this influence. Adopting a quantitative research approach with experimental methods, the researchers employed a post-test-only design using cluster random sampling. Class VII-A was designated as the experimental group, while Class VII-B was the control group. Data were gathered through a post-test essay examination. Analytical techniques involved prerequisite tests (normality and homogeneity) and hypothesis testing (t-test and effect size). Results indicated a significance level of 0.008 in the t-test and an effect size of 0.685, suggesting that using Wordwall media has a moderate yet significant positive effect on students' mathematical concept representation skills. The findings reveal that incorporating Wordwall edugames in classroom instruction can enhance students' mathematical representation capabilities, foster an interactive learning environment, and improve students' self-expression. Consequently, Wordwall has been proven to elevate student engagement in learning and can effectively supplement traditional classroom instruction.
Research Trends in Teacher Digital Competencies: A Bibliometric Review
Authors: Butar Butar Senita , Haniva Respita , Mulyadi Hari
Published: July 2024

Teacher digital competence (TDC) is a pivotal skill in 21st-century education, essential for addressing the extensive educational demands of the digital age and technological advancements. This study aims to investigate and evaluate research trends in teacher digital competency from 2013 to 2023 using descriptive bibliometric analysis. Researchers utilized the Scopus database for data collection, following a four-stage process to obtain 235 publications. These publications were then analyzed using the VOS Viewer software. The findings of this study are as follows: 1) The research trend on TDC has shown a continuous increase from 2013 to 2020; 2) Citation trends peaked in 2018, with the work of Gudmundsdottir and Hatlevik (2018) being the most frequently cited; 3) Spain emerged as the leading country in this field, with 100 publications and five international collaborations; 4) Research on teacher digital competence primarily focuses on digital competence itself, higher education, ICT, digital technology, digital e-learning, personnel training, educational technology, digital devices, digital resources, teaching and learning, motivation, digital skills, digital literacy, TPACK, information and communication technologies, professional development, professional digital competence, self-assessment, education, and teacher professional development. Recent themes such as digital teaching competence, improvement, and digital tools are recommended for further research on teacher digital competence.
Chip Product Development Based on Business Management and Creativity Training in Magelang District
Authors: Hassani Rofi Abul , Tidar Zidan Zakaria , Alfiyanto Dwi Janu , Marella Mita , Saputri Cindy Febrina Eka , Septiana Syahadenita Eka
Published: July 2024

This activity aims to overcome the problems faced by partners where these problems make it difficult for partners to develop. The culinary chip industry is one of the businesses owned by the residents of Wonogiri Lor Hamlet, Kapuhan Village, Sawangan District, the majority of the population of Wonogiri Lor Village are farmers. As for the business partner sector itself, it is a culinary industry in the form of various chips which usually consist of mushroom, intestine, bitter melon, spinach, melinjo chips, and so on. Based on information extracted from business owners, there are at least four problems faced by partners, namely: lack of knowledge about management, especially marketing management, product packaging that usually only uses ordinary plastic, no business licensing, and efforts to increase revenue. The aspect of capital which has been an important problem for a business entity, in this case partners, is also constrained regarding capital because the capital used by partners is their own capital so they have not received capital support from the village or from the district government. In overcoming these problems, we try to provide solutions by targeting the Human Resources (HR) aspect. HR is one of the important aspects in an organization because it is HR that runs other aspects of an organization. We are trying to strengthen the human resources of partner organizations by providing several programs such as providing business management training, marketing training for chips culinary business partners to strengthen human resources and marketing chips for Mrs. Ana's industrial business.
Comparative Study of Economic Learning Outcomes Using Problem Based Learning and Project Based Learning Models by Considering Student Learning Activities
Authors:   Universitas Lampung, Saputra Jaya , Rusman Tedi , Suroto Suroto , Rahmawati Fanni
Published: July 2024

This study aims to explore the effectiveness of problem-based (PBL) and project-based (PjBL) learning models on students' economic learning outcomes with different learning activity levels. Using a quasi-experimental method with a 2x2 factorial design and a purposive sample of 67 students, data were collected through interviews, observations, documentation, tests, and experiments. Hypothesis testing was done with two-way ANOVA and t-test of two independent samples. The results showed no significant difference in economic learning outcomes between PBL and PjBL models. However, there was a significant difference between students with high and low learning activities. The average learning outcomes of students with high learning activities were better using PjBL, while students with low learning activities were better using PBL. There was no significant interaction between learning models and learning activities on economic learning outcomes. This research provides important insights for educators in choosing the appropriate learning model to improve economic learning outcomes.
Menilik Komik Shingeki no Kyojin melalui Kacamata Masyarakat Simulasi Baudrillard
Authors: Yuwono Ardian Indro , Anindita Rizky Maulana
Published: July 2024

Hajime Isayama’s Shingeki no Kyojin tells the disruption on Paradis Island’s stability as Titans ambush. This article found the Paradis Island is the perfect representation of Jean Baudrillard’s simulacra society which is trapped in a chaos of reality and simulations in hyperreality. Through the Barthes’s semiotic model, this article finds that Paradis Island’s a perfect hyperreal site that traps its inhabitants in simulacra and blurs anything beyond the wall. Repression and propaganda complicate people’s understanding on politics. In reflection to current state, media are trapping society inside walls of their preferences to blur the reality behind or beyond the wall.
Development of Learning Media with Power Point Application Based on iSpring Suite 11 in Arabic Language Learning
Authors: Ainiyah Nur , Massi Sarwansyah , Nuroniyah Wifayatun , Bahri Ratni Bt. Hj. , Mohd Zakaria Zarima Binti
Published: July 2024

The development of science and technology today constrain the educators to adapt, use, or even develop tools or applications as learning media, including Arabic language learning. In MTs Al-Yusra Gorontalo City, digital technology has been utilized as Arabic language learning media, with most teachers using PowerPoint programs for teaching, but the designs are still simple and not interactive. Therefore, this article aimed to develop Arabic language learning media based on digital technology with interactive multimedia designs using PowerPoint program based on iSpring Suite 11 and test its feasibility. This research method is Research and Development (R&D) method with the ADDIE development model. The subjects of this study were eighth-grade students of MTs Al-Yusra Gorontalo City, with a sample size of 20. Media expert assessment, subject matter expert, language expert, students, and teachers were used as research data and analyzed descriptively in percentage. Based on this research, a product was obtained with a subject matter expert assessment of 82% in the highly valid category, media expert assessment of 82.5% in the highly valid category, and language expert assessment of 73.3% in the quite valid category. Students' response to media usage was in the good category with a score of 72%, and teachers' response to the ease of media usage was 76%. Based on these research results, it can be concluded that interactive multimedia with Power Point application based on iSpring Suite 11 in Arabic language subjects is feasible to be used as Arabic language learning media.
Optimizing the Assessment of Qawa’id Materials by Utilizing Wordwall Media
Authors: Erlina Erlina , Ainin Moh. , Rosyidi Rosyidi , Zulpina Zulpina , Lando Natalia S.
Published: July 2024

This research was initiated by the apprehension experienced by students in qawa’id material tests and the lack of digital-based media, especially qawa’id assessments. The primary objectives of this study were to create an assessment tool based on Wordwall media for evaluating qawa’id material, to depict the assessment environment before and after the implementation of this media and to evaluate the feasibility and usability of the product. The data were collected through interviews with Arabic language teachers in MAN 2 Payakumbuh, 35 tenth grade students in the second semester of the 2023/2024 academic year, and questionnaires for expert validation and student responses. The findings of this study indicated that : 1). There was a noticeable contrast in the atmosphere of qawa’id test activities before and after the utilization of Wordwall media-based assessment tools, leading to a reduction in students’ apprehension. 2). After conducting a structured research stage, according to linguists and media experts, the product was considered feasible with a percentage of 80% and very feasible with 99% and 85%. 3). Teachers and students found the product to be highly practical, with an acceptance rate of 85.13%. The integration of Wordwall in the qawa’id assessment process served as a strategy to alleviate student apprehension during qawa’id assessments. Qawa’id assessment based on Wordwall media developed in this study was both feasible and practical to be implemented by Arabic language teachers for tenth-grade students in the second semester.