bluuebunny/crossref_metadata_2025 huggingface dataset:
MENINGKATKAN PERAN SERTA MASYARAKAT DALAM UPAYA MENUJU DESA MANDIRI DAN TANGGUH DITENGAH WABAH
Authors: Subayani Nataria Wahyuning , Alfajar Yulfanani , Rahaweni Mirna Hanes
Published: August 2022

In the midst of the COVID-19 pandemic, many residents have been affected both economically, in terms of education and health. The need for counseling or education to the surrounding community on the importance of taking care of yourself, especially protecting yourself from the Covid-19 virus. With several work programs carried out by the group 1 KKN team in their respective villages, it is hoped that they can help the government in suppressing the spread of the COVID-19 virus. Besides protecting ourselves is the first step to take care of the people around us. When people ignore the importance of taking care of themselves, especially ignoring health protocols, it also affects those around us. After the work program is carried out by members of group 1 KKN, it is hoped that the community will be able to protect themselves and always comply with the health protocols that have been set to maintain mutual safety
Dekspantenol, Sıçanlarda LPS'nin Neden Olduğu Akut Akciğer Hasarında Artan VCAM-1 ve Kaspaz-3 Ekspresyonlarını Azaltarak İnflamasyonu ve Apoptozu İnhibe Eder
Authors: KARAKUYU Nasıf Fatih , ÖZMEN Özlem
Published: August 2022

This study aims to investigate the effects of Dexpanthenol (Dex), a stable alcoholic analogue of D-pantothenic acid which has anti-oxidant, antiapoptotic, and antiinflammatory properties, on lipopolysaccharide (LPS)-induced lung damage via caspase-3 (cas-3) and vascular cell adhesion molecule-1 (VCAM-1) levels. According to the experimental plan of study, thirty-two Wistar Albino species rats were distributed randomly into four groups as control, LPS (5 mg/kg, intraperitoneally (i.p), single dose), LPS (30 minutes before last Dex treatment) + Dex (500 mg/kg, i.p, for 3 days) and Dex. After six hours of LPS application, lung tissues of the rats were taken for histopathological, immunohistochemical and biochemical examinations. According to results of the study, LPS causes hyperemia, neutrophil leukocyte chemotaxis and thickened septal tissue on lung. Inducing inflammation by increasing VCAM-1 levels and triggers apoptosis by increasing cas-3 levels in lung tissue. In addition, LPS decreased total antioxidant status levels, which is a marker of anti-oxidant capacity, and increased oxidative stress index and total oxidant status values, which are indicators of oxidative stress. Dex has shown its effect by reversing all these alterations and normalizing the values. These results suggest that Dex can be used as a preservative to reduce LPS-induced acute toxicity in the lung.
LPS ile Indüklenen Septisemik Koyunlarda Bazı Eser Element Konsantrasyonlarının İncelenmesi
Authors: ALTINOK YİPEL Fulya , YİPEL Mustafa
Published: August 2022

Enfeksiyona karşı düzensiz immünolojik konak yanıtına bağlı meydana gelen organ bozukluğu olarak tanımlanan endotoksemi, koyunlarda yüksek mortalite ve morbidite sonucu ciddi ekonomik kayıplara neden olan bir hastalıktır. Çalışmada septisemi oluşturulmayan sağlıklı (kontrol) koyunlar (n=6) ile septisemi oluşturulan koyunlardan (n=6) alınan plazma ve serum örneklerinde makro (Ca, Mg, Na, K, P) ve mikro (Fe, Cu, Se, Zn) esansiyel element konsantrasyonları belirlendi. Sonuçlara göre Ca, K ve Se konsantrasyonları açısından gruplar arasındaki farklar istatistiksel olarak anlamlıydı (p≤0.05). Septik hastalarda başarılı teşhis ve tedavi, yeni biyobelirteç belirlenebilmesi ve mekanizmalarının açıklanabilmesi açısından ICP-MS gibi hassas analiz yöntemlerinin kullanıldığı elementler konsantrasyonları ve değişimleri üzerine kapsamlı çalışmalara ihtiyaç duyulmaktadır.
Экономический рост или гармоничное социально-экономическое развитие? Часть III. Оценка индексов гармоничного развития регионов России
Authors: Шмат В.В.
Published: August 2022

Статья продолжает цикл публикаций, посвященных исследованию возможностей комплексной оценки результатов социально-экономического развития, базирующейся на совместном учете факторов устойчивости, инклюзивности и инновационности в сочетании с фактором экономического благосостояния. Ранее автором была предложена методическая концепция оценивания, обоснован выбор инструментария в виде аппарата факторного анализа по методу главных компонент (одного из методов многомерного статистического анализа), представлены и подвергнуты анализу практические результаты построения индекса гармоничного развития, полученные на примере ведущих экономик мира. С использованием разработанной методики и с учетом ранее полученных практических результатов проведены расчеты индекса для регионов – субъектов Российской Федерации для ряда контрольных лет за период времени с 2000 по 2019 гг. и составлены соответствующие рейтинги. Выявлены основные социально-экономические характеристики регионов, которые наиболее существенно определяют степень гармоничности развития. Результаты исследования направлены на совершенствование методов оценки социально-экономического развития регионов России, расширение возможностей анализа и обоснования государственной экономической и региональной политики.
Быть ли органическому сельскому хозяйству в России: взгляд участников отрасли
Authors: Кравченко Н.А. , Самусенко С.А. , Зимнякова Т.С. , Дробышев И.А.
Published: August 2022

В статье приводятся результаты эмпирического исследования состояния органического сельского хозяйства в России, основанные на качественных углубленных интервью с представителями отрасли – фермерами, производителями органических средств защиты растений, сотрудниками научных и образовательных организаций. Анализируются исторические предпосылки возникновения отрасли, систематизируются стимулы, а также барьеры и ограничения развития производства органических продуктов. Показано, что основные стимулы развития отрасли имеют преимущественно неэкономическую природу и связаны с личными убеждениями участников, их приверженностью ценностям здорового образа жизни, бережного отношения к окружающей среде и сохранению сельского образа жизни. Барьеры развития отрасли классифицированы на барьеры производителя, барьеры потребителя, институциональные ограничения. Приведены мнения респондентов о состоянии и перспективах отрасли, даны рекомендации по возможным направлениям государственной поддержки сектора органического сельского хозяйства в России.
THE EFFECT OF PEOPLE AND CLOSE ENVIRONMENT ON THE VOTING BEHAVIOR OF TURKISH FEMALE VOTES MEMBERS OF DIFFERENT ETHNIC GROUPS: LOCAL ELECTIONS SİVAS PROVINCE
Authors: ERGÜL GÜVENDİ Nurgül
Published: August 2022

Abstract

In this study, the influence of Turkish women voters from their spouses and close circles during the voting process and the changes that this interaction shows between women with different ethnicities were investigated. In this context, a face-to-face questionnaire was applied to 500 female voters, who were determined by stratified sampling among 124,921 female voters registered in Sivas Central electoral rolls and identifying themselves with different ethnic affiliations (Alevi, Circassian, Kurdish, Turkish Sunni, Armenian). Our results show that with an average of 3.6, Kurdish women are predominantly influenced by their spouses and close circles, Circassian women are undecided with an average of 3.0, Sunni Turkish women and Armenian women are not affected by their spouses and close circles with an average of 2.1. Finally, our findings show that Alevi women are the women who are least affected by their spouses and close circles while voting, with an average of 1.6.
Coronaviruses: Troubling Crown of the Animal Kingdom
Authors: Gozalo Alfonso S , Clark Tannia S , Kurtz David M
Published: August 2022

The existence of coronaviruses has been known for many years. These viruses cause significant disease that primarily seems to affect agricultural species. Human coronavirus disease due to the 2002 outbreak of Severe Acute Respiratory Syndrome and the 2012 outbreak of Middle East Respiratory Syndrome made headlines; however, these outbreaks were controlled, and public concern quickly faded. This complacency ended in late 2019 when alarms were raised about a mysterious virus responsible for numerous illnesses and deaths in China. As we now know, this novel disease called Coronavirus Disease 2019 (COVID-19) was caused bySevere acute respiratory syndrome-related-coronavirus-2(SARS-CoV-2) and rapidly became a worldwide pandemic. Luckily, decades of research into animal coronaviruses hastened our understanding of the genetics, structure, transmission, and pathogenesis of these viruses. Coronaviruses infect a wide range of wild and domestic animals, with significant economic impact in several agricultural species. Their large genome, low dependency on host cellular proteins, and frequent recombination allow coronaviruses to successfully cross species barriers and adapt to different hosts including humans. The study of the animal diseases provides an understanding of the virus biology and pathogenesis and has assisted in the rapid development of the SARS-CoV-2 vaccines. Here, we briefly review the classification, origin, etiology, transmission mechanisms, pathogenesis, clinical signs, diagnosis, treatment, and prevention strategies, including available vaccines, for coronaviruses that affect domestic, farm, laboratory, and wild animal species. We also briefly describe the coronaviruses that affect humans. Expanding our knowledge of this complex group of viruses will better prepare us to design strategies to prevent and/or minimize the impact of future coronavirus outbreaks.
Internal Combustion Engine Modeling Framework in Simulink: Combustion Modeling
Authors: Yoon Hwan-Sik
Published: August 2022

An internal combustion engine modeling framework has been developed in the MATLAB/Simulink environment to allow engine component blocks to be connected in a physically representative manner to reduce the model build time. Each component block, derived from physical laws, interacts with other blocks according to block connection. In this series paper, detailed combustion modeling is presented among several engine subsystems. In the engine modeling framework, combustion is represented by a spherical flame propagating from the spark plug, and the burn rate is correlated to combustion chamber geometry, laminar flame speed, and turbulence. To accurately predict the burn rate, the quasi-dimensional model requires tuning. The combustion model has been computationally validated in a previous study and will be experimentally validated with real engine test data in the next series paper.
Abiotrophia spp. and Granulicatella spp. Infective Endocarditis: A Contemporary Perspective
Authors: Estévez Agustín , Marín Mercedes , Sánchez-Carrillo Carlos , Machado Marina , Alcalá Luís , Pinilla Blanca , Delgado Antonia , González-Ramallo Víctor , Pedraz Álvaro , Martínez-Sellés Manuel , Bouza Emilio , Valerio Maricela , Muñoz Patricia , GAME-HGUGM on behalf of
Published: August 2022

Background: Abiotrophia spp. and Granulicatella spp. are Gram-positive cocci, formerly known as nutritionally variant or deficient Streptococcus. Their role as causative agents of infective endocarditis (IE) is numerically uncertain, as well as diagnostic and clinical management of this infection. The aim of our study is to describe the clinical, microbiological, therapeutic, and prognosis of patients with IE caused by these microorganisms in a large microbiology department. Methods: Retrospective analysis of all the patients with Abiotrophia spp. and Granulicatella spp. IE registered in our centre in the period 2004–2021. Results: Of the 822 IE in the study period, 10 (1.2%) were caused by Abiotrophia spp. (7) or Granulicatella spp. (3). The species involved were A.defectiva (7), G.adiacens (2) and G.elegans (1). Eight patients were male, their mean age was 46 years and four were younger than 21 years. The most frequent comorbidities were congenital heart disease (4; 40%) and the presence of intracardiac prosthetic material (5; 50%). IE occurred on 5 native valves and 5 prosthetic valve or material. Blood cultures were positive in 8/10 patients, within a mean incubation period of 18.07 hours. In the other two patients, a positive 16SPCR from valve or prosthetic material provided the diagnosis. Surgery for IE was performed in seven patients (70%) and in all cases positive 16S rRNA PCR and sequencing from valve or prosthetic material was demonstrated. Valves and/or prosthetic removed material cultures were positive in four patients. Nine patients received ceftriaxone (4 in monotherapy and 5 in combination with other antibiotics). The mean length of treatment was 6 weeks and IE-associated mortality was 20% at one year follow-up. Conclusions: Abiotrophia spp. or Granulicatella spp. IE were infrequent but not exceptional in our environment and particularly affected patients with congenital heart disease or prosthetic material. Blood cultures and molecular methods allowed the diagnosis. Most of them required surgery and the associated mortality, in spite of a mean age of 46 years, was high.
Computational Repurposing of FDA Approved Drugs Against Monkeypox Virus Cysteine Proteinase: A Molecular Docking and Dynamics Simulation Study.
Authors: Odhar Hasanain Abdulhameed
Published: August 2022

Monkeypox is a zoonotic disease caused by a DNA virus known as Monkeypox virus. Generally, Monkeypox disease is considered a self-limiting condition with symptoms similar to that of smallpox disease. Most cases of Monkeypox are considered mild but some patients may suffer from serious complications. Due to the high similarity between Monkeypox virus and smallpox virus, therefore vaccines and antiviral therapies originally intended for use against smallpox can be effective also in Monkeypox infection cases. However, the level of cross-immunity against poxviruses had declined globally because of cessation of vaccination campaigns against smallpox decades ago. As a result, the recent outbreaks in 2022 of Monkeypox in multiple regions of the word have caused public health fears of a new pandemic potential. It is well-known that Monkeypox virus like other poxviruses replicates in the cytoplasm of infected cells by using a number of viral encoded proteins like cysteine proteinase. Generally, proteases enzymes play a critical role in viral replication cycle through catalysis of precursor polyproteins cleavage. Therefore, proteases enzymes like cysteine proteinase represent an attractive target to design novel antiviral drugs. Unfortunately, the cysteine proteinase enzyme of Monkeypox virus is still not yet crystallized and this can negatively impact efforts for structure-based drug design and screening. As such, we have chosen to computationally model the secondary and tertiary structures of Monkeypox cysteine proteinase by using the primary amino acids sequence of the enzyme. And after refinement and validation of the modelled protein, we have screened a library of 1,615 FDA approved drug molecules against Monkeypox cysteine proteinase by using AutoDock Vina. Then, the best hits were further assessed by molecular dynamics simulation for 20 nanoseconds. The aim of this in-silico study is to repurpose approved drugs as a potential inhibitor against Monkeypox cysteine proteinase. The findings of this in-silico study refer to the potential ability of the antibiotic Tetracycline to inhibit the cysteine proteinase of Monkeypox virus. However, the lack of crystallization data regarding this proteinase enzyme makes these findings not conclusive.
Sikap Sosial Tokoh Utama dalam Novel Orang Miskin Dilarang Sekolah Karya Wiwid Prasetyo, Pendekatan Psikologi Sastra
Authors: Najamudin
Published: August 2022

Sikap Sosial Tokoh Utama dalam Novel Orang Miskin Dilarang Sekolah Karya Wiwid Prasetyo, Pendekatan Psikologi Sastra
Kontemplasi Cinta dan Perjuangan
Authors: Najamudin
Published: August 2022

Buku yang ada dihadapan pembaca ini adalah akumulasi kontempalasi yang memiliki banyak values, karena menyimpan muatan edukasi dan kritik konstruktif yang dikemas lewat narasi-narasi sastrawi. Semua diksi yang digunakan dalam setiap bait dari puisi yang ada memiliki makna peyoratif yang multi tafsir dari pembaca. Tapi itulah asyiknya kita bermain kata-kata membuat pembaca menjadi penasaran akan makna dan substansinya.
Estimation of country-level effects in cross-national survey research using multilevel modelling: The role of statistical power
Authors: Damian Elena , Meuleman Bart , van Oorschot Wim
Published: August 2022

Multilevel regression analysis is one of the most popular types of analyses in cross-national social studies. However, since its early applications, there have been constant concerns about the relatively small numbers of countries in cross-national surveys and its ability to produce unbiased and accurate country-level effects. A recent review of Bryan and Jenkins (2016) highlights that there are still no clear rules of thumb regarding the minimum number of countries needed. The current recommendations vary from 15 to 50 countries, depending on model complexity.This paper aims to offer a better understanding regarding the consequences of group-level sample size, model complexity, effect size, and estimator procedure on the precision to estimate country-level effects in cross-national studies. The accuracy criteria considered are statistical power, relative parameter bias, relative standard error bias, and convergence rates. We pay special attention to statistical power - a key criteria that has been largely neglected in past research. The results of our Monte Carlo simulation study indicate that the small number of countries found in cross-national surveys seriously affects the accuracy of group-level estimates. Specifically, while a sample size of 30 countries is sufficient to detect large population effects (.5), the probability of detecting a medium (.25) or a small effect (.10) is .4 or .2, respectively. The number of additional group-level variables (i.e., model complexity) included in the model does not disturb the relationship between sample size and statistical power. Hence, adding contextual variables one by one does not increase the power to estimate a certain effect if the sample size is small. Even though we find that Bayesian models have more accurate estimates, there are no notable differences in statistical power between Maximum Likelihood and Bayesian models.
Exploring enablers and barriers to implementing the Transparency and Openness Promotion (TOP) Guidelines: A theory-based survey of journal editors
Authors: Naaman Kevin , Grant Sean , Kianersi Sina , Supplee Lauren , Henschel Beate , Mayo-Wilson Evan
Published: August 2022

The Transparency and Openness Promotion (TOP) Guidelines provide a framework for journals to develop open science policies. Theories of behaviour change can guide understanding of why journals do (not) implement open science policies and the development of interventions to improve these policies. In this study, we used the Theoretical Domains Framework to survey 88 journal editors on their capability, opportunity, and motivation to implement TOP. Likert-scale questions assessed editor support for TOP, and enablers and barriers to implementing TOP. A qualitative question asked editors to provide reflections on their ratings. Most editors supported adopting TOP at their journal (71%) and perceived other editors in their discipline to support adopting TOP (57%). Most editors (93%) agreed their roles include maintaining policies that reflect current best practices. However, most editors (74%) did not see implementing TOP as a high priority compared to other editorial responsibilities. Qualitative responses expressed structural barriers to implementing TOP (e.g., lack of time, resources, and authority to implement changes) and varying support for TOP depending on study type, open science standard, and level of implementation. We discuss how these findings could inform the development of theoretically-guided interventions to increase open science policies, procedures, and practices.
Detail, Valence, and Gender of Shared Memories Influences Social Support and Liking
Authors: Wong Chun Hei , Sukhani Ritika Satish , Boddez Yannick , Raes Filip , Barry Tom Joseph
Published: August 2022

The sharing of autobiographical memories (AM) serves vital social functions such as eliciting social support from others. The current study investigated the contribution of different properties of shared memories (emotional valence, detail) and the sharer (gender) in influencing the amount of offered social support and liking following self-disclosure. Participants (N = 258) were shown 16 profiles of both male and female individuals that each shared an AM varying in detail and valence. Participants were asked to rate how much emotional and instrumental support they would offer to, as well as how much they liked, each profile. Participants preferred and offered more social support to high-detail profiles in comparison to low-detail profiles. An effect of valence was also found, where positive affective profiles were offered more instrumental support than negative profiles. The opposite was true for emotional support. These effects were further moderated by profile gender where men who shared high-detail negative memories were offered more support in comparison to low-detail memories. Conversely, women who shared low-detail negative memories were offered more support than those who offered high-detail memories. These effects were consistent across both men and women participants. Differences in the way we share high versus low-detail, and positive versus negative memories, as well as our gender, can influence the extent to which other people like us and offer support to us. These findings contribute to our understanding regarding why some people may not receive the support they need.
Assumed agreement about paranoid conspiracies in social networks protects against distress
Authors: Suthaharan Praveen , Corlett Philip R.
Published: August 2022

Paranoia is the belief that others intend you harm. It is related to conspiracy theories, wherein those others represent an organized faction, coordinating the harm against self and others, and violating societal norms. Current psychological studies of paranoid conspiracy theorizing focus either on the individual or their broader social network. Likewise, theories of belief formation and updating often contain individual level processes as well as broader interpersonal and organizational factors. Here we examine paranoia and conspiracy theorizing in terms of individual behavioral predictors (performance on a probabilistic reversal learning task which assays belief updating) as well as social sensing: we ask participants to report the features of their social network, including whether their friends and acquaintances share their paranoid conspiratorial beliefs. We find that people who believe paranoid conspiracy theories expect more volatility during the task. They also assume that members of their social network share their paranoid beliefs. Critically, those participants with larger social networks and greater assumed belief tend to harbor their conspiratorial beliefs with less emotional distress and expect less volatility in the task. This is evidence that, like political and religious beliefs, conspiracy theories may flourish under a sacred canopy of belief consensus. These data suggest that friends and acquaintances may serve as sources of credulity and moving between them may sustain conspiracy beliefs when there is detraction. This hybrid individual/social account may shed light on clinical paranoia and persecutory delusion, wherein disability is defined normatively, and social supports are fewer.
Sensitive Liberals and Unfeeling Conservatives? Interoceptive Sensitivity Predicts Political Liberalism
Authors: Ruisch Benjamin , Von Mohr Mariana , Naber Marnix , Tsakiris Manos , Fazio Russell , Scheepers Daan
Published: August 2022

The stark divide between the political right and left is rooted in conflicting beliefs, values, and personality—and, recent research suggests, perhaps even lower-level physiological differences between individuals. In this Registered Report, we investigated a novel domain of ideological differences in physiological processes: interoceptive sensitivity—that is, a person’s attunement to their own internal bodily states and signals (e.g., physiological arousal, pain, and respiration). We conducted two studies testing the hypothesis that greater interoceptive sensitivity would be associated with greater conservatism: one laboratory study in the Netherlands using a physiological heartbeat detection task and one large-scale online study in the U.S. employing an innovative webcam-based measure of interoceptive sensitivity. Contrary to our predictions, we found evidence that interoceptive sensitivity may instead predict greater political liberalism (vs. conservatism), although this association was primarily limited to the American sample. We discuss implications for our understanding of the physiological underpinnings of political ideology.
The Development of Lexical Processing: Real-Time Phonological Competition and Semantic Activation in School Age Children
Authors: Jeppsen Charlotte , Apfelbaum Keith S , Tomblin Bruce , Klein Kelsey , McMurray Bob
Published: August 2022

Prior research suggests that real-time word recognition processes are stabilized in early childhood (Fernald et al., 2006). However, recent work suggests that development of these processes continues throughout adolescence (Huang & Snedeker, 2011; Rigler et al., 2015). This study aimed to investigate whether these developmental changes are based solely within the lexical system, or are due to domain general changes. This study also aimed to investigate the development of real-time lexical-semantic activation. We captured semantic activation phonological competition and non-linguistic domain general processing skills using two Visual World Paradigm experiments in 43 7-9-year-olds, 42 10-13-year-olds, and 30 16-17 year-olds. Older children were quicker to fixate the target word and exhibited earlier onset and offset of fixations to both semantic and phonological competitors. Visual/cognitive skills explained significant, but not all, variance in the development of these effects. Developmental changes in semantic activation were largely attributable to changes in phonological processing. These results suggest that the concurrent development of linguistic processes and broader visual/cognitive skills lead to developmental changes in real-time word recognition, while semantic activation is stable across these ages.
Identifying facilitators of early access to care among Canadian Forces Health Services personnel
Authors: Frank Christine , Born Jennifer
Published: August 2022

LAY SUMMARY

Despite the importance of the mental and physical well-being of Canadian Forces Health Services (CFHS) personnel, research suggests they may be under-accessing care. A lot of research has looked at what factors prevent individuals from accessing care (i.e., barriers), but almost none has examined what encourages individuals to access care (i.e., facilitators). In addition to examining which facilitators encourage CFHS personnel to access care, this study also examined whether facilitators directly impacted care-seeking behaviour, or whether they also indirectly influence behaviour by impacting general intentions to access care. Results showed that prioritizing one’s health directly and indirectly influenced care-seeking for both mental and physical health issues. Having the support of senior leadership influenced intention to seek care for mental health issues. Easy access to care influenced intention to seek care for physical health issues. Ensuring CFHS personnel prioritize their own health, have the support of senior leadership, and have easy access to care will help promote early access to care.
Towards a Neural Network Hypothesis for Functional (Dissociative) Amnesia: Catastrophic Forgetting
Authors: Larner Andrew , Larner Andrew
Published: August 2022

Functional amnesia, also known as dissociative amnesia, psychogenic amnesia, or mnestic block syndrome, is a rare disorder which, although clinically heterogeneous, is most often characterised by dense retrograde amnesia mainly affecting the episodic-autobiographical domain but with relative preservation of anterograde memory function, a pattern dissimilar to that seen in other amnesic disorders. The pathogenesis of functional amnesia remains unknown. Here, appeal is made to the study of artificial neural networks in the hope that, as in other mnestic disorders, this might give insight into the mechanisms underpinning functional amnesia. Specifically, the observation of catastrophic forgetting or catastrophic interference occurring in artificial neural networks, that is the abrupt and complete loss of previously learned information when learning new information, is extended to the human nervous system to develop a novel hypothesis: the Catastrophic Forgetting Hypothesis of functional amnesia.
Biliary Colic Presenting as Right-Sided Cervical Radiculopathy
Authors: De Volkaersbeke Alexander Kervyn , De Volkaersbeke Alexander Kervyn , Taylor Angela , Habibi Behnum
Published: August 2022

A 50-year-old female patient presented with several weeks of right-sided neck, posterior shoulder, and arm pain suggestive of cervical radiculopathy. Her diagnostic workup included cervical spine x-rays and a cervical spine MRI which showed degenerative changes and mild cervical spinal stenosis. She was evaluated by a spine surgeon and a pain medicine specialist. Multiple treatments were administered without success, including courses of celecoxib and gabapentin. Several rounds of epidural steroid injections were also administered, with only transient relief. Upon developing acute right upper quadrant abdominal pain and undergoing a laparoscopic cholecystectomy for biliary colic, the patient reported resolution of her chronic right neck, posterior shoulder, and arm pain.
METHODS OF USE STAGE RECEPTIONS IN PROCESS OF LABOR TRAINING
Authors:   Полтавський національний педагогічний університет імені В. Г. Короленка, KOLISNYK E. , TSYNA A. ,   Полтавський національний педагогічний університет імені В. Г. Короленка
Published: August 2022

In the article to substantiate the integral system of methods of personality development by means of theatrical pedagogy in labor education of primary school pupils. To achieve this goal at different stages of scientific research used the method of systematization of theoretical and empirical data to design methods for the systematic use of acting in the labor of primary school pupils. The aim of the study was to find suitable for existing concepts of personality development ways to use theatrical skills in labor education and upbringing of pupils, methods of their systematic use, which would clarify educational outcomes and the ratio of variables in the description of components of personality development. The main strategy of research of methods of systematic use of acting, which would correspond to conceptual approaches to personality development was the formulation of working definitions in the form of descriptions of goals, objectives, principles, content, methods and forms of organization of formation and development of components. in the lessons of labor training. The results of the study testify to the achievement of its goal and the solution of the tasks to substantiate the methods of systematic use of acting in lessons of labor training, aimed at: development of pupils (the method of mandatory participation of all pupils in collective creativity pupils skillfully demonstrated by the teacher in the lesson of labor actions); development of properties of cognitive mental processes of the pupil’s personality (methods of physical actions, creation of creative well-being, historical parallels, change of role positions, effective analysis); use of personal qualities of each pupil in mastering the educational material (sketch method, methods of stage exercises of pupils in memory of physical actions, stylistic improvisational tasks-dramatizations); acquisition by students of the ability to transfer the model of communication through the use of artistic skills for role-playing images (step-by-step method of teaching students artistic skills); conditionality of the results of educational influences by the level of the pupil's own activity (group sketch improvisations based on the works of classics of painting). Key words: theater pedagogy, labor training, acting techniques.
USE OF WEB-BASED ENVIRONMENTS IN THE STUDY OF COMPUTER DESIGN BY STUDENTS OF INFORMATIVE HIGH SCHOOL
Authors:   Національний педагогічний університет імені М. П. Драгоманова, KORETS M. , PIDHORNA T. ,   Державний торговельно-економічний університет, SYMONENKO K. ,   Національний педагогічний університет імені М. П. Драгоманова
Published: August 2022

With the development of modern technologies, computer hardware and various software, there are rapid and high-quality changes in data processing technologies. Web-oriented technologies, which are the advanced technologies of the information society, play the role of a leading tool for informatization of education. The development of software used in the study of computer design. The article substantiates the need to use web-based learning environments in the process of studying computer design by high school students of informative high school. During the study of computer science at school, it is planned to perform educational tasks both in lessons at school and at home. Providing all students with access to unified software is problematic because everyone has different computers, including different operating systems. Starting from March 12, 2020, student learning has been taking place remotely for a long time. Most computer science teachers have faced the problem of how to unify software for mastering educational material in computer science lessons. One way to solve this problem is to use web-based environments. Types of computer design are considered and in accordance with the age characteristics of students and learning objectives selected web-based software which greatly simplifies the organization and implementation of the educational process. When using web-based environments, you do not need additional knowledge to configure them, because the use of such environments is independent of the technical characteristics of the computer, and only requires an Internet connection. Keywords: computerization of education, computer design, computer graphics, web-based environment, information and communication technologies.
Development of Secured Knowledge Management system using Information Technology Model
Authors: Al-Hashemy Rageed Hussein Hussan
Published: August 2022

Information Technology (IT) has contributed to the development of many areas, including the development of companies and in accordance with the requirements of the free market, so it has become necessary to contribute to the development of the knowledge management system because of its importance in the use and dissemination of knowledge through the IT model that focuses on all the requirements of the knowledge management system. And the factors affecting its development, this model is characterized by meeting the needs of the system and upgradable, as well as being comprehensive and integrated (with other systems). The model is designed in several programming languages ​​such as (C#, PHP and MySQL) and according to business requirements in addition to its ease of use so that everyone can use it (employees, clients, partners), and that the model has the ability to identify obstacles and errors that cause non-development, In terms of communication, it uses all technical resources (interviews, video conferences, chat rooms, etc.) to contribute to enhancing teamwork and communication, enhancing expertise and processing data and relying on human expertise to promote innovation and knowledge acquisition to achieve the real objective of this study which is to develop a knowledge management system.
Influence of clinical and radiological parameters on the likelihood of neurological improvement after surgery for degenerative cervical myelopathy
Authors: Toop Nathaniel , Gifford Connor S. , McGahan Ben G. , Gibbs David , Miracle Shelby , Schwab Jan M. , Motiei-Langroudi Rouzbeh , Farhadi H. Francis
Published: August 2022

OBJECTIVE

Degenerative cervical myelopathy (DCM) is routinely treated with surgical decompression, but disparate postoperative outcomes are frequently observed, ranging from complete neurological recovery to persistent decline. Although numerous clinical and radiological factors have been independently associated with failure to improve, the relative impact of these proposed risk factors remains obscure. In this study, the authors assess the combined role of clinical and radiographic parameters in contributing to failure to attain neurological improvement after surgery.

METHODS

A consecutive series of patients who underwent surgery for DCM between July 2013 and August 2018 at a single institution was identified from a prospectively maintained database. Retrospective chart review was undertaken to record perioperative clinical and radiographic parameters. Failure to improve on the last follow-up evaluation after surgery, defined as a change in modified Japanese Orthopaedic Association (mJOA) score less than 2, was the primary outcome in univariate and multivariate analyses.

RESULTS

The authors included 183 patients in the final cohort. In total, 109 (59.6%) patients improved (i.e., responders with ΔmJOA score ≥ 2) after surgery and 74 (40.4%) were nonresponders with ΔmJOA score < 2. Baseline demographic variables and comorbidity rates were similar, whereas baseline Nurick score was the only clinical variable that differed between responders and nonresponders (2.7 vs 3.0, p = 0.02). In contrast, several preoperative radiographic variables differed between the groups, including presence and degree of cervical kyphosis, number of levels with bidirectional cord compression, presence and number of levels with T2-weighted signal change, intramedullary lesion (IML) length, Torg ratio, and both narrowest spinal canal and cord diameter. On multivariate analysis, preoperative degree of kyphosis at C2–7 (OR 1.19, p = 0.004), number of levels with bidirectional compression (OR 1.83, p = 0.003), and IML length (OR 1.14, p < 0.001) demonstrated the highest predictive power for nonresponse (area under the receiver operating characteristic curve 0.818). A risk factor point system that predicted failure of improvement was derived by incorporating these 3 variables.

CONCLUSIONS

When a large spectrum of both clinical and radiographic variables is considered, the degree of cervical kyphosis, number of levels with bidirectional compression, and IML length are the most predictive of nonresponse after surgery for DCM. Assessment of these radiographic factors can help guide surgical decision-making and more appropriately stratify patients in clinical trials.
Prospects for the growth of non-primary non-energy exports of the Russian Federation to the countries of North Africa
Authors: Progunova Lada V.
Published: August 2022

The relevance of the study is due to the increased interest in promoting non-primary non-energy exports of the Russian Federation to the markets of North Africa in the context of the emerging global trend of abandoning hydrocarbons, including from Russia. The article presents the results of the analysis of non-primary non-energy exports of Russia to the markets of North Africa by stages of processing based on statistical data on exports from Russia to these states over the past five years. The leading approach to the study of this issue is the method of economic and statistical analysis, which allows a comprehensive examination of economic processes in the sphere of non-energy exports. Also, by applying the Balassa index, an assessment of the comparative advantage of Russia by groups of commodity items in the markets of the countries of the region is given.
Based on the data obtained, the author concludes that Russia has prospects for the growth of exports of goods of traditional export specialization, increasing the export of products of medium and upper stages of processing, promoting Russian consumer goods to the markets of North African countries and gives recommendations to support Russian enterprises when entering the North African markets.
Also, this study raises the question of the definition of non-primary products, which is a key factor in determining the volume of exports of non-primary non-energy goods in the analysis. Discrepancies were revealed in approaches to classifying products as non-primary in the definitions of the international and Russian classification systems for export products.
Eurasian Economic Union and African countries: Problems and prospects of cooperation
Authors: Volkov Sergey N.
Published: August 2022

In March 2022, the Center for Russian-African Relations and Foreign Policy of African Countries Studies of the Institute for African Studies of the Russian Academy of Sciences held a conference with international participation on the topic “Cooperation of the members of the Eurasian Economic Union with African countries”.

The Conference took place at a difficult time, when the international situation sharply worsened that required a rethinking of our country’s relations with the outside world as a whole and with important partners, including the states of Africa and our closest neighbors, the countries of the Eurasian Economic Union (EAEU), where Russia is also a member. The event, which was held in the format of a videoconference, was attended by leading Russian specialists in African studies, the scholars from the Institutes of the Russian Academy of Sciences, the Institute of Economics of the National Academy of Sciences of Belarus, workers of practical organizations, including the Eurasian Economic Commission, teachers, post-graduate students and applicants.

Among the main problems discussed there were: Session 1 - global aspects of contemporary international relations and prospects of multilateral cooperation; Session 2 - bilateral cooperation of the EAEU members with African countries; Session 3 - positions of the maincompetitors for EAEU countries in Africa. The reports contained recommendations on strengthening Russia’s mutually beneficial partnershipwith the EAEU member states and African states. These recommendations may be used practically by both the business community, as evidenced by the interest in this conference from a number of Russian companies, and by practical organizations of the EAEU members.
The light from the stern: South African historians in the era of COVID-19
Authors: Gorelik Boris M.
Published: August 2022

South Africa was among the few countries on the African continent where medical historians were often called on to reassure the public that the new pandemic could be contained and that lockdowns were bound to end. During the coronavirus pandemic, the role of South African medical historians has been to put historically informed perspectives on the virus outbreaks and their consequences.
For 750 days, South Africa remained in a national state of disaster because of the COVID-19 pandemic. The imposition of lockdown in 2020 increased hunger and poverty, deprived more South Africans of their income and access to education, placed a heavy burden on the healthcare and public health sector, sparked off protest and looting of shops, caused excessive use of violence by security forces and worsened the recession. The pandemic exacerbated the disparities in health, living conditions and access to professional medical services.
Epidemics affect all spheres of people’s lives and lead to noticeable social change. The study of epidemics puts the past in a different perspective by foregrounding historically important tendencies and processes. Therefore, the popular media in South Africa sought the opinion of the leading experts in this field, such as Howard Phillips, on the coronavirus disease throughout the state of disaster period.
The impact of the public scholarship by Phillips and his colleagues during the coronavirus pandemic in South Africa demonstrates that knowledge gained from historical research can help people to make sense of the present, which is crucial ‘in a time of plague’. That is, historical knowledge can be useful in solving today’s problems. Uncovering patterns of responses to epidemics by previous generations of South Africans throughout the centuries, medical historians helped the nation realise that it had already been in dangerous waters before, survived, recovered and might do it again.
Development of high-yielding varieties of soft winter wheat in the conditions of the southeastern Steppe of Ukraine
Authors:   Donetsk State Agricultural Research Station of NAAS, Vyskub R. S. , Chuhrii H. A. ,   Donetsk State Agricultural Research Station of NAAS, Bondareva O. B. ,   Donetsk State Agricultural Research Station of NAAS
Published: August 2022

Topicality. One of the conditions to increase stably the soft winter wheat yield is plant breeding with high plasticity and resistance to adverse environmental factors, pests and diseases. Issues. Development of new high-yielding varieties with higher resistance to adverse weather conditions is important to increase crop produc-tivity. Aim. To create the initial material and high-yielding varieties of soft winter wheat in conditions of insuffi-cient soil moisture in the southeastern Steppe of Ukraine. Materials and methods. The research was conducted according to B. Dospekhov's method of field experience. The research was conducted in the 2017–2020 on the SE Research Farm Zaboishchyk of Donetsk State Agricultural Research Station NAAS at the Rozlyv village, Volnovakha district, Donetsk region. The field trials were conducted in the selective crop rotation of the Donetsk State Agricultural Research Station. The predecessors were black fallow and corn for grain. Research methods: hybridological, field, laboratory, mathematical and statistical methods. Results. According to the research results, it was found that the 77 numbers selected from hybrid combinations were left in the control nursery for further study. Among them were three numbers hk 363, hk 353, hk 403 which largest exceeded the standard by 14.1–19.7%. There are 42 numbers studied in a small competitive variety trial. It was determined that 15 hybrid combinations were the best than the standard (Donetska 48 variety) by 0.03–1.57 t/ha. In the competitive variety trial, 21 winter wheat cultivars after black fallow, and 25 cultivars after maize for silage were studied. According to yield, the best hybrid combinations after fallow were hk 4, hk 863/2, hk 716/1, which exceeded the standard Donetsk 48 by 0.41–0.51 t/ha, and after maize for silage, the best hybrid combinations were hk 321, hk 363, hk 318, in which the increase to the standard yield was 0.39-0.47 t/ha. According to the grain yield, the best varieties in the ecological variety trial were Bohynia, Popeliushka, Dyvo donetske, Oberih Myronivskyi, Yuzovska, Ihrysta, Peremoha, Patriotka, which exceeded the Donetsk 48 standard variety by 0.35-0.68 t/ha. Conclusions. It was determined that the development of new high-yielding varieties of soft winter wheat will increase productivity due to their adaptability for growing conditions in the southeastern Steppe of Ukraine. According to the analysis of the research results, the steppe ecotype varieties demonstrate a significant advantage on all the studied indicators; they better realize their genetic potential in specific soil and climatic conditions. Key words: breeding, winter wheat, hybridization, variety, yield.