bluuebunny/crossref_metadata_2025 huggingface dataset:
Galling-Free Cold and Warm Forging of Titanium Wires to Flat Plates by SiC-Coated SiC dies
Authors: Aizawa Tatsuhiko , Yoshino Tomoaki , Shiratori Tomomi , Fukuda Tatsuya
Published: April 2021

Pure titanium and titanium alloys were difficult to be forged and press-forged because of their easiness in galling to die and punch surfaces during metal forming. β-SiC coated SiC dies were developed to perform a galling free cold forging of pure titanium wire up to the higher reduction of thickness than 50%. Since the thickness of this SiC coating was 4 mm, various cavities and micro-punches were formed into coating by micro-machining. The pure titanium and β-phase titanium alloy wires were employed as a work for cold and warm forging to investigate the effect of flow stress on the forging behavior up to the reduction of thickness by 70% under the controlled holding temperature. The contact interface of β-SiC coating to the work was precisely analyzed to describe the in situ solid lubricating process on the interface. The free carbon agglomerates isolated at the center of contact interface from the carbon supersaturated β-SiC coating, and, worked as a solid lubricant to prevent the β-SiC coating punch and die from galling during forging under high reduction of thickness.
A method for three-dimensional modelling of the shear-clinching process
Authors: Han Daxin , Yang Chen , Meschut Gerson
Published: April 2021

Three-dimensional modelling enables to determine the in-plane material flow in asymmetrical situation. Thus, the distortion of the sheets to be joined can be characterized more exactly. This study shows a method for building up a three-dimensional shear-clinching framework without damage criteria. In fact, the die-sided sheet in shear-clinching was designed as a pre-punched sheet and slugs. The material separation in the die-sided joining partner, which in two-dimensional simulation is often described by macro- and micromechanical fracture criteria, was realised in this study based on a defined contact condition. By means of a shear-cutting simulation, a correlation between the break angle and the separation stress was determined, which was used as a separation criterion in the shear-clinching simulation. The separation line was confirmed using post-particles. To validate this model, the results of the simulation using a quadratic single-point specimen were compared to the experiments with respect to the distortion of the joining partner. In general, the built three-dimensional framework provides for further tool developments with regard to the reduction of distortion in shear-clinching.
Contact pressure and sliding velocity ranges in sheet metal forming simulations
Authors: Cillaurren Joseba , Galdos Lander , Sanchez Mario , Zabala Alaitz , Saenz de Argandoña Eneko , Mendiguren Joseba
Published: April 2021

In the last few years many efforts have been carried out in order to better understand what the real contact between material and tools is. Based on the better understanding new friction models have been developed which have allowed process designers to improve numerical results in terms of component viability and geometrical accuracy. The new models define the coefficient of friction depending on different process parameters such as the contact pressure, the sliding velocity, the material strain, and the tool temperature. Many examples of the improvements achieved, both at laboratory scale and at industrial scale, can be found in the recent literature. However, in each of the examples found in the literature, different ranges of the variables affecting the coefficient of friction are covered depending on the component analysed and the material used to produce such component. The present work statistically analyses the contact pressure and sliding velocity ranges achieved during numerical simulation (FEM) of sheet metal forming processes. Nineteen different industrial components representing a high variety of shapes have been studied to cover a wide range of casuistic. The contact pressure and sliding velocity corresponding to typical areas of the tooling have been analysed though numerical simulation in each case. This study identifies the ranges of contact-pressure and sliding velocities occurring in sheet metal forming aimed to set the characterization range for future friction studies.
Effects of Thickness Changes and Friction during the Thermoforming of Composite Sheets
Authors: White Kari D. , Campshure Blake , Sherwood James A.
Published: April 2021

In composite sheet preforming, the combination of binder-ring force and friction induce in-plane tension that mitigates the onset of wrinkling, but too much force can induce tearing. Thus, the processing conditions must be designed to strike a balance between these competing manufacturing-induced defects. Compounding the challenge to prescribe the appropriate processing conditions is the potential change in thickness of the sheets as a function of in-plane shear. The variation in the thickness from point to point in the ply stack will result in a nonuniform pressure under the binder ring. In the current research, the preforming step is simulated using a discrete mesoscopic modeling approach in LS-DYNA. Thickness-stretch shell elements are used to capture the evolution in the sheet thickness and the in-plane shear stiffness of the deformed sheet. Finite element simulations and preforming experiments are completed for the same processing conditions. The preliminary results for the punch force as a function of displacement, the state of shear over the part surface, and the distribution and magnitude of the wrinkles showed excellent correlation between the model and the experiment. The simulation results show that the shape of the punch force vs. tool depth curve gives insight into the onset of wrinkles. The simulation is then used to predict a binder-ring force that would mitigate wrinkle formation in a four-layer preform.
Melt strengthening of polylactic acid and its blends: Shear and elongation rheological investigations of the forming process
Authors: Maazouz Abderrahim , Lamnawar Khalid
Published: April 2021

Polylactic acid (PLA) can be a good alternative to petroleum-based polymers thanks to its organic origin and its biodegradability. This study introduces some promising routes for enhancing the processability of PLA, which presents several challenges due mainly to the poor shear and elongation properties of this biopolymer. To our knowledge, this is the first paper dedicated to an investigation of foaming and/or blown extrusion of PLA that focuses on structural, rheological and thermomechanical properties. Two main routes were selected: (i) the modification of its structural, rheological and thermomechanical properties and (ii) blending the PLA with another ductile, thermoplastic biopolymer such as poly (butylene adipate-co-terephthalate) (PBAT) or polyamide (PA11). Various formulations of PLA with multifunctionalized epoxy, nucleating agents and plasticizer were prepared and characterized on the basis of their linear viscoelasticity and extensional properties. The balance of chain extension and branching was also investigated using solution viscosimetry, steric exclusion chromatography (SEC) and rheology (shear and elongation rheology). On one hand, a batch foaming process assisted by supercritical CO2 was carried out. The influence of the foaming parameters, the extent of chain modification and the contribution of crystallization to cell morphology were all evaluated. Based on these parameters, structures ranging from micro to macro-cellular-cell were obtained. On the other hand, the stability maps of blown extrusion for neat and modified PLA were established at different die temperatures. We succeeded in greatly enhancing the blown extrusion windows of PLA, achieving high blow-up ratio (BUR) and take-up ratio (TUR) values. We were able to demonstrate that faster kinetics of crystallization can also be reached for chain-extended and branched PLA formulated with adequate amounts of nucleating agents and plasticizers. Through this work, blown films with intriguing thermomechanical and mechanical properties were produced using an optimal formulation for PLA.
Numerical investigations on the influence of the weld surface and die geometry on the resulting tensile stresses in the joining zone during an extrusion process
Authors: Behrens Bernd-Arno , Duran Deniz , Uhe Johanna , Matthias Tim
Published: April 2021

Bulk metal components are often used in areas which are subjected to very high loads. For most technical components, a distinction between structural and functional areas can be made. These areas usually have very different loading profiles, sometimes with contradictory requirements. Nevertheless, nowadays almost only monomaterials are used for the production of bulk metal components. With increasing requirements towards more and more efficient products with lower weight, compact design and extended functionality, these materials are reaching their material-specific limits. A significant increase of product quality and economic efficiency can be expected exclusively with locally adapted properties by combining different materials within one component. In this regard, the focus of this contribution is the production of a hybrid pinion shaft made of the material combination steel (37CrS4) and aluminium (AW6082). The tool concept for extrusion of the hybrid preform, the simulation-based design of the forming process as well as the material characterisation are presented. With the help of the FE-simulation, different serially arranged semi-finished component geometries were investigated in order to minimise the occurring tensile stresses in the component during the extrusion process to prevent failure during forming.
Identifying conformational isomers of organic molecules in solution via unsupervised clustering
Authors: Marinova Veselina , Dodd Laurence , Lee Song-Jun , P. F. Wood Geoffrey , Marziano Ivan , Salvalaglio Matteo
Published: April 2021

We present a systematic approach for the identification of statistically relevant conformational macrostates of organic molecules from molecular dynamics trajectories. The approach applies to molecules characterised by an arbitrary number of torsional degrees of freedom and enables the transferability of the macrostates definition across different environments. We formulate a dissimilarity measure between molecular configurations that incorporates information on the characteristic energetic cost associated with transitions along all relevant torsional degrees of freedom. Such metric is employed to perform unsupervised clustering of molecular configurations based on the fast search and find of density peaks algorithm. We apply this method to investigate the equilibrium conformational ensemble of Sildenafil, a conformationally complex pharmaceutical compound, in different environments including the crystal bulk, the gas phase and three different solvents (acetonitrile, 1-butanol, and toluene). We demonstrate that, while Sildenafil can adopt more than one hundred metastable conformational configurations, only 12 are significantly populated across all the environments investigated. Despite the complexity of the conformational space, we find that the most abundant conformers in solution are the closest to the conformers found in the most common Sildenafil crystal phase.
Cyclic(Alkyl)(Amino)Carbene Ligands Enable Cu-Catalyzed Markovnikov Protoboration and Protosilylation of Terminal Alkynes: A Versatile Portal to Functionalized Alkenes
Authors: Gao Yang , Yazdani Sima , Kendrick Aaron , Junor Glen , Grotjahn Douglas , Bertrand Guy , Jazzar Rodolphe , Engle Keary
Published: April 2021

Regioselective hydrofunctionalization of alkynes represents a straightforward route to access alkenyl boronate and silane building blocks. In previously reported catalytic systems, high selectivity is achieved with a limited scope of substrates and/or reagents, with general solutions lacking. Herein, we describe a selective copper-catalyzed Markovnikov hydrofunctionalization of terminal alkynes that is facilitated by strongly donating cyclic (alkyl)(amino)carbene (CAAC) ligands. Using this method, both alkyl- and aryl-substituted alkynes are coupled with a variety of boryl and silyl reagents with high α-selectivity. The reaction is scalable, and the products are versatile intermediates that can participate in various downstream transformations. Preliminary mechanistic experiments shed light on the role of CAAC ligands in this process.
How to Manipulate Through-Space Conjugation and Clusterolumi-nescence of Simple AIEgens with Isolated Phenyl Rings?
Authors: Zhang Jianyu , hu lianrui , Zhang Kaihua , LIU Junkai , Li Xingguang , Wang Haoran , Wang Zhaoyu , Sung Herman H.-Y. , williams ian duncan , Zeng Zebing , Lam Jacky W. Y. , Zhang Haoke , Tang Ben Zhong
Published: April 2021

Apart from the traditional through-bond conjugation (TBC), through-space conjugation (TSC) is gradually proved as another important interaction in photophysical processes, especially for the recent observation of clusteroluminescence from nonconjugated molecules. Herein, simple and nonconjugated triphenylmethane (TPM) and its derivatives with electron-donating and electron-withdrawing groups were synthesized, and their photophysical properties were systematically studied. TPM was characterized with visible clusteroluminescence due to the intramolecular TSC. Experimental and theoretical results showed that the introduction of electron-donating groups into TPM could red-shift the wavelength and increase the efficiency of clusteroluminescence simultaneously, due to the increased electronic density and stabilization of TSC. However, TPM derivatives with electron-withdrawing groups showed inefficient or even quenched clusteroluminescence caused by the vigorous excited-state intramolecular motion and intermolecular photoinduced electron transfer process. This work provides a reliable strategy to manipulate TSC and clusteroluminescence.
The Density Matrix via Few Dominant Observables: The Quantum Interference in the Isotope Effect for Atto-Pumped N2
Authors: Komarova Ksenia , Remacle Francoise , Levine Raphael D.
Published: April 2021

In our paper a compact representation of the density as a function of a few observables is examined for the coupled electron-nuclear dynamics unfolding on three electronic states. The time-evolution of the density, populations and coherences, is accurately captured by the time-evolution of only nine coefficients, the Lagrange multipliers of these observables. We use a specific example of the isotope effect in atto-pumped N2 to show that both classical and quantal effects of mass are well reproduced by this compact description. Simple analytical results for the surprisal are given, which allows a factorization of these two effects.
Crystal Structures of Streptomyces Coelicolor Methylmalonyl-CoA Epimerase with Substrate or Transition State Analog Contradicts a Simple General Acid-Base Catalytic Mechanism
Authors: Stunkard Lee M , Benjamin Aaron B , Bower James , Huth Tyler , Lohman Jeremy
Published: April 2021

Crystal structures of Streptomyces coelicolor methylmalonyl-CoA epimerase in the holo-form, with substrate or the putative transition state analog, 2-nitroproionyl-CoA. The proposed catalytic mechanism is general acid-base catalysis. The proposed catalytic residues are too far from the substrate or analog, unless conformational changes take place or some other mechanism is used.
Значение эластографии в реальном времени в диагностике рака простаты
Authors: Азаб Х. А. , Родович В. В.
Published: April 2021

Цель: оценить клиническую значимость трансректальной эластографии в реальном времени (TРЭ) в диагностике рака предстательной железы (PПЖ).Методы: в исследование были включены 195 пациентов с повышенным уровнем ПСА. Анализ кривой ошибок (ROC) проводился для оценки диагностической эффективности TРЭ.Результаты: баллы TРЭ у пациентов с PПЖ и доброкачественным состоянием составляли 3,20 ± 1,11 (диапазон: 1–5) и 2,24 ± 1,01 (диапазон: 1–4), соответственно (P <0,001). Наилучшее пороговое значение показателя TРЭ составило 3, а чувствительность, специфичность, точность в диагностике РПЖ составили 68,6% (35/51), 69,4% (100/144) и 69,2% (135/195), соответственно. Точность TРЭ при объеме ПЖ ≤30 мл была значительно выше, чем в группе объема ≥50 мл и в группе 30–50 мл (76,9% против 65,0% и 76,9% против 71,4%, в обеих группах P <0,001). Точность оценки TРЭ была выше для пациентов с ПСА в диапазоне 4–10 нг/мл, чем для пациентов с ПСА > 10 нг/мл (85,3% против 66,7%, P = 0,002).Вывод: полуколичественная оценка жесткости предстательной железы может служить полезным методом скрининга для пациентов с подозрением PПЖ, особенно для тех, у которых повышенный уровень ПСА не сопровождается клиническими проявлениями.
First record of the raccoon dog Nyctereutes procyonoides (Gray, 1834) in Luxembourg
Authors: Schley Laurent , Jacobs Marianne , De Sousa Tiago , Hatlauf Jennifer
Published: April 2021

Short notes don't have an abstract
Intracellular ways of development of Alzheimer's disease against the background of herpes viral infections (literature review)
Authors: Ostrovska S.S. , Shatorna V.F. , Liholetov E.O.
Published: April 2021

The concept of the viral etiology of Alzheimer's disease (AD) was first proposed in 1982. Its author MJ Ball suggested that the herpes simplex virus (HSV1) may be involved in the pathogenesis of AD, finding that the areas of the brain damaged in acute herpetic encephalitis are the same as those that are affected in AD, and those who survived usually suffer from memory loss and other cognitive impairment typical of AD. Subsequently, in all postmortem brain samples (temporal, frontal, and hippocampal) viral sequences of the viral thymidinekinase gene were found in a high proportion (70-100%) both in AD and in elderly people without it, while in young people and children the virus was found in very low proportions, so it was suggested that HSV1 comes from the peripheral ganglia, where the virus can remain inactive for many years, then enters the brain at an older age due to a decrease in the activity of the immune system. The increased risk of AD is associated with the presence of HSV1 in the brain and the carriage of a specific genetic factor – allele-ε4 of the apolipoprotein E4 gene (APOE-ε4). By themselves, neither HSV1 nor the APOE-ɛ4 allele were found as risk factors for the development of AD but their combination increased the risk of AD development by 12 times and made up 60% in patients with AD. The phenomena involved in the pathophysiology of AD are neurodegenerative changes that occur as a result of fibrillation and deposition of amyloid-β-peptide (Aβ) and neurofibrillary tangles – accumulations of aggregated phosphorylated tau-proteins (P-tau), leading to brain atrophy due to neuronal death. Traditionally, Aβ has been characterized as a catabolic by-product. However, it has recently been shown that Aβ-peptide has antiviral activity and protective effects against HSV infections in the brain. А 16-year study in Thailand with more than 33,000 patients showed that long-term use of antiherpetic drugs reduces the risk of dementia, including AD patients infected with HSV1. Patients with HSV1 infection who received antiherpetic drugs showed a lower risk of all types of dementia compared with the group without these drugs. Their positive effect on stopping the accumulation of amyloid beta and tau protein in the body has been confirmed. In this regard, it is assumed that vaccination against HSV1 may be useful not only for treatment, but also for the prevention of AD.
Analysis of the krok1 and histology subtests dynamics of students of Dnipropetrovsk medical academy
Authors: Pototskaya O.Yu. , Shevchenko K.M. , Averkina L.I. , Kobeza P.A.
Published: April 2021

Оbjective control of the level of knowledge in medical universities is the basis for guaranteeing the quality of education. There are a lot of examples of universal systems designed to evaluate medical students in different countries, including USMLE, IFOM and others; particularly in Ukraine Krok 1 licensed exam is conducted since 2005. Results of Krok 1 are also used for ranking medical universities at the national level. The purpose of our work was to conduct a comparative analysis of the results of the licensing exam Krok 1, in particular, a histology subtest, among students of specialties 221 “Dentistry” and 222 “Medicine” and different languages of education (Ukrainian, Russian, English) in Dnipropetrovsk medical academy. We have revealed that all the analyzed contingents of students (DMA as well as Ukrainian) in the majority of observation periods from 2014 to 2019 had lower average results on histology compared to average Krok 1 results. This could be explained by low quota of histological tests for students of specialty 222 “Medicine” which is 4-6%, and absence of the threshold level for doing each particular subject. These conditions do not motivate students of the third course to recollect a complicated discipline that ended more than a year ago. Another problem is in the content of anchor questions in Krok 1 booklets: the number of such questions are distributed unevenly among booklets of different years and different languages of study. As a result, students with different languages of study are put in unequal conditions. In addition, the variation in the number of anchor tests from year to year, the lack of a declared quota of such tests disorients students and makes it difficult to develop algorithms for preparing for Krok 1.
Dynamics of pain syndrome and quality of life in the application of vertebroplasty in patients with vertebral fractures against osteoporosis
Authors: Stashkevych A.T. , Shevchuk A.V. , Uleshchenko D.V. , Martynenko V.G. , Melenko V.I.
Published: April 2021

Currently, insufficient attention is being paid to an issue of the necessary anti-osteoporotic therapy after percutaneous vertebroplasty for vertebral fractures associated with osteoporosis, which leads to premature termination of medical treatment and worsening of the treatment results in this group of patients.  An objective of the research is to study the results of treatment of patients with vertebral fractures associated with osteoporosis, depending on the use of anti-osteoporotic therapy. The results of percutaneous vertebroplasty of 91 postmenopausal women aged 50-90 years, depending on the use of anti-osteoporotic therapy during the postoperative period were analysed.  An assessment was made according to the dynamics of pain syndrome using the Visual Analogue Scale (VAS), the Quality of Life Scale by J.R. Gaughen to estimate the patient's mobility and a need for pain medication. The results of the treatment were assessed 3 and 6 months after the percutaneous vertebroplasty. Bone mineral density was measured using Dual-energy X-ray absorptiometry 6 month after the treatment. Anti-osteoporotic therapy, which was prescribed for all patients comprised calcium supplements, antiresorbents and in D-hypovitaminosis – alfacalcidol or cholecalciferol. Only half of the patients followed the recommendations – 46 (50.6%), while the rest of the patients stopped the therapy in 2-3 months due to the improvement of their condition. In the main group of patients, where necessary anti-osteoporotic therapy was administered, significant reduction of pain syndrome and increase in quality of life during 3 and 6 months’ observation period were revealed. In the group of patients where prescribed anti-osteoporotic therapy was not adhered, significant reduction of pain syndrome and increase in quality of life in the observation period 3 months was revealed but deterioration in the form of pain syndrome increase and decrease in quality of life in the observation period of 6 months occurred. Effectiveness of anti-osteoporosis therapy, with regard to measuring bone mineral density can be reliably confirmed only in the main group. Intraoperative and postoperative complications occurred up to 5.5%, and generally did not require further treatment and did not affect the overall treatment result. Thus, it was revealed that to ensure a stable effect after the surgery, long-term prescription of anti-osteoporosis therapy is needed.
Ifluence of seasonity on vitamin D level in patients with HCV infection and healthy people
Authors: Nikolaychuk M.A. , Shostakovych-Koretskaya L.R. , Budayeva I.V. , Biletska S.V.
Published: April 2021

According to WHO, about 150-200 million people are currently infected with the HCV virus worldwide. Recently, in the professional literature, the number of publications on the role of vitamin D in patients with viral hepatitis C has increased as vitamin D metabolism occurs with the participation of the liver and its deficiency is associated with an increased risk of infectious diseases. The aim of this study was to investigate the effect of seasonal factor on vitamin D (25 hydroxycalciferol) levels in patients with chronic viral hepatitis C and healthy subjects. The study involved 100 patients in the registry of patients with chronic viral hepatitis in the Dnipropetrovsk region. The prevalence and deficiency of vitamin D in patients with chronic viral hepatitis C and conditionally healthy subjects at different times of the year were determined, which showed the presence or absence of a seasonal effect on serum 25(OH)D level. Patients were divided into two groups, depending on the time of the year (autumn-winter and spring-summer), in which the level of 25 (OH) D was determined. The serum was metabolised by vitamin D, which is synthesized by the liver – 25 hydroxycalciferol (25 (OH) D), an indicator of the supply of vitamin D to the human body. Vitamin D levels were evaluated according to the M.F. Holick classification. According to the level of vitamin D patients were divided into 3 groups (patients with normal level, insufficient (suboptimal) level and vitamin D deficiency). The results of the study showed no effect of seasonal factor on the level of 25 (OH) D in the serum of patients with chronic viral hepatitis C. Vitamin D levels are controlled by the time of the year: in spring and summer this indicator is normal, in autumn and winter – seasonal decrease in vitamin D.
The impact of COVID-19 on the economic and accounting transformation
Authors: Микола Петрович Городиський  , Дмитро Миколайович Захаров  , Ігор Віталійович Орлов
Published: April 2021

The coronacrisis accelerated the process of economic digitization. New technologies are changing approaches to the organization of labor, as a result of a process of changing classic business models. The competitive environment in all market sectors is changing. Businesses at all levels are working to integrate technology for creating a sustainable, mobile, and digital business model. Accordingly, to ensure this process, technical support in the form of data hubs, data centers, etc. is required. Strategies of digitalization of different countries are considered. It is determined that the digitization process provides these basic factors for the beginning of qualitative changes: infrastructure upgrades, expansion of databases, widespread mobile devices with a high level of communication capabilities, increasing accessibility and expanding the use of the Internet. As a result, digitalization leads to a general «connection» and the total impact of these processes on all sectors of the economy: industry, transport, finance, health, education, and others. For an objective assessment of performance and business opportunities, it is proposed to include in the management report information on development prospects, key risks, the achievement of declared goals, and strategic plans, taking into account the degree of consequences caused by the COVID-19 pandemic. Businesses should review their accounting and reporting policies to provide accurate and up-to-date information on stakeholder performance.
Історичні аспекти створення першого вищого навчального закладу індустріальної освіти Волинської губернії
Authors: Віктор Валерійович Євдокимов  , Оксана Вікторівна Олійник  , Андрій Васильович Морозов  , Андрій Олегович Чагайда
Published: April 2021

Революція 1917 року та громадянська війна, що розпочалася після неї, фактично зруйнували соціально-економічні зв’язки та призвели до масової зупинки виробництв, відновлення яких було вкрай необхідне новій владі. Однією із найбільших проблем індустріально-технічної галузі стала відсутність достатньої кількості фахівців, адже значна кількість представників української інтелігенції залишила країну і не мала намірів повертатися з-за кордону. Підприємства потребували не лише інженерів, для підготовки яких не вистачало наукових та педагогічних кадрів, а й фахівців середньотехнічного рівня освіти. Для цього на виробництвах створювали освітні заклади, які не могли дати своїм слухачам достатнього рівня знань і лише готували фактично висококваліфікованих та ідеологічно мотивованих робітників. Випускники таких заводських технічних закладів мали вузьку спеціалізацію без фундаментального загальнотехнічного та освітнього рівня, але хотіли загального визнання своїх дипломів Народним комісаріатом освіти УСРР, що призвело до ретельної перевірки технікумів та закриття більшості із них у першій половині 20-х років ХХ століття.
Information provision of value-based management of enterprise brands: strategic landmarks
Authors: Сергій Федорович Легенчук  , Тетяна Петрівна Остапчук  , Ігор Віталійович Орлов
Published: April 2021

The necessity of solving the problem of information support of brand value-based management of enterprise has been grounded. The existence of accounting dysfunction as a means of information support of value-based brand management has been stated. Peculiarities of normative regulation of accounting of brands and trade marks according to the international and national legislation have been analyzed. The reasons for the prohibition of capitalization of internally generated brands in the accounting legislation have been analyzed. The concept of the moribund effect in terms of accounting and evaluation of internally generated brands of the enterprise has been defined. Critical approaches of scientists to the recognition and accounting of internally generated and received from the company's brands have been analyzed. Three paradoxes of accounting for brands have been allocated. Two main ways to improve the current methodology of accounting for brands in order to overcome the dysfunction of the accounting system (making revolutionary changes in the methodology of accounting for brands; the creation of accounting engineering add-ons) have been suggested.
Features of accounting and information risk management in the conditions of impact of COVID-19
Authors: Вікторія Костянтинівна Макарович  , Олена Олександрівна Григоревська  , Наталія Степанівна Стойка
Published: April 2021

The purpose of the article is to develop theoretical provisions and develop guidelines for improving approaches to accounting for risks of exposure to COVID-19 and disclosure of information about them in the reporting of economic entities. In the process of research the methods of observation, comparison, analysis, synthesis, generalization were used. The study is based on the hypothesis that high-quality accounting and information support will increase the validity, efficiency and analytical information about the risks of COVID-19 and their impact on business activities in accordance with modern management requirements, strengthening the responsibility of performers, improving management accounting. The article summarizes the approaches to the impact of uncertainty and risk on the accounting and analytical system of enterprises, which are considered in scientific circles by domestic researchers. The risks of the enterprise’s activity that are relevant in the conditions of the COVID-19 pandemic are highlighted: risks caused by restrictions by legislative and regulatory acts; risks due to the occurrence of obligations related to the production and sale of products, goods, works, services; risks of asset impairment; risks to the recognition and measurement of liabilities; risks of possible bankruptcy; investment risks. to identify risk and assess it, you can use the «triple method». It is established that the accounting and information support of risk management in the conditions of influence of COVID-19 includes: methodical support of risk accounting, analytical support, documentary support; display of information on risks in the reporting, which allowed developing a report on the risks of the impact of COVID-19 on the activities of the enterprise. The obtained results are the basis for bringing the system of accounting and analytical support to a qualitatively new level and will generate useful, truthful and relevant information for enterprise management in decision-making to minimize the impact of risks on business activities through COVID-19.
Leveraging a lean region based on blockchain technology
Authors: Чік Марія Юріївна , Макурін Андрій Андрійович
Published: April 2021

This article summarizes the arguments and counterarguments in the framework of the scientific discussion on the use of economical accounting in production, considering modern technologies of waste utilization. The main objective of the study is to conduct an analysis of the emergence of waste in various sectors of the national economy of Ukraine. The main ways of utilization of waste are determined. Systematization of literary sources and approaches to solving the problem allowed us to determine the problems of the operation of lean accounting and lean production. After analyzing the proposed problems of domestic and foreign scientists regarding the implementation of lean accounting, it is appropriate to conclude that the main obstacle to the establishment of a system of lean accounting is the lack of a definite methodological approach for the implementation of such a system. The urgency of solving this scientific problem is that to determine the ways of utilization of waste, it is necessary to keep an account of them considering the usefulness of the use of waste. An important area of research in the accounting system is the allocation of lean accounting and the latest concept of management of a production enterprise, which is aimed at eliminating the losses of production resources – lean production. The high level of organization of lean accounting is no longer a factor in achieving success, but the result. Obtaining a high level of organization of accounting processes (both basic and auxiliary) will allow the company to save a significant amount of resources. Among the fact that the concept of lean accounting involves fundamentally new approaches to the culture of management and accounting organization at the enterprise. Investigating the issue of conducting business operations related to the use of waste in production, its storage, utilization is necessary for the formation of a proper system of accounting and information support for the adoption of management decisions on the recycling the waste and the use of modern waste recycling technologies. The methodical tools of the conducted research were the methods of empirical analysis, the method of observation and generalization of the results of the conducted research. The research object was chosen by the industrial sector of Ukraine.
All Feelings are Queer Feelings: Queer Worlding Through Affect in the Films of Xavier Dolan
Authors:   , Cunningham George
Published: April 2021

The highly stylised melodramas of Québécois filmmaker Xavier Dolan use particular affects to represent queerness and express how normative social conventions impact queer lives. This thesis analyses the functions of shame in I Killed My Mother (2009), rage in Laurence Anyways (2012), disgust in Tom at the Farm (2013), and nostalgia in Mommy (2014) to convey conflicts between queerness and heteronormativity. Formal analysis of Dolan’s films is paired with queer and affect theories to clarify his queer worlding - in other words, the objects and symbols that construct Dolan’s queer cartography. Informed by Jack Halberstam’s theory of queer temporality, this thesis investigates Dolan’s portrait of heterosexual norms’ influence on the affective worlding of queer lives. While the focus is on queer temporalities, scholarship on queer childhood, rurality, and utopia also illuminate Dolan’s singular style. Kathryn Bond Stockton’s work on queer childhood sheds light on the cyclical nature of shame depicted in I Killed My Mother, while Susan Stryker’s account of trans rage demonstrates the function of colour in Laurence Anyways. Furthermore, queer theories of disgust inform Tom at the Farm’s subversion of the rural gay cowboy trope. Finally, concepts of nostalgia validate the sonic doubling of music in Mommy to promote queer utopian values. Ultimately, this analysis of affect, form, and style highlights how Dolan’s cinema spotlights the transformative power of negative affects to displace heteronormativity with queer worldviews.
O Mais Querido Brazil - The Most Beloved of Brazil
Authors: Tosic Branislav
Published: April 2021

Since the early stages of stadium design, landscape architecture has frequently been overlooked, with the space surrounding these structures relegated to providing parking and accessways. In other words, rather than give consideration to creating aesthetically appealing spaces, the tendency has instead been to create sterile and unappealing concrete jungles, that pay little or no attention to how the users might experience the space as they move through it. This effectively means that potentially attractive public spaces are not being utilised, which is increasingly problematic as urban areas become ever more densely populated.

This issue will be considered by proposing a series of ideas that could be used in the development of a new stadium for the Brazilian football club Flamengo. This club, which is one of the biggest and most popular in South America, currently has its home at the

Maracana stadium in Rio de Janeiro. As a result of the privatisation of the previously publicly-owned stadium, Flamengo has decided that it would prefer to develop a new stadium on an entirely new site in Rio.

The fundamental aim of this research thesis is to demonstrate how landscape architecture can be used to inform the development of stadiums in such a way that the sites surroundings stadiums can become attractive and functional spaces in their own right, that will appeal to a diverse demographic. In other words, rather than being no more than a carpark and accessway, attractive only to those attending an event at the stadium, the surrounding site should be a place that people would wish to visit for itself. To achieve this, the design must take into account a number of key factors, including where the stadium is situated with respect to the surrounding urban landscape, as well as how the stadium relates to the people who will be the primary users. The intention is to create a space surrounding the stadium that is wholly integrated, both physically and socially, with both the adjacent community and the club’s supporters who will travel there to make use of the many resources on offer at the stadium. Issues that are particular to this site, such as how best to turn a previously industrial site into one that is attractive and ecologically viable are also addressed as part of this thesis.

This design-led research will show how landscape architecture can administer key elements to stadium design, through connection to the urban fabric and fan experience. Exploiting these elements with evidence through the use of adaptive, flexible and also fixed design strategies of sustainability, resilient and regenerative landscape solutions will be achieved between the existing urban setting and Flamengo’s new home.
Palliative surgical treatment of patients, suffering proximal tumoral affection of biliary ducts and the jaundice syndrome
Authors: Susak Ya. M. , Palytsya R. Ya. , Markulan L. Yu. , Dyrda O. O.
Published: April 2021

Objective. To compare the efficacy of methods of miniinvasive palliative treatment of malignant hilar strictures with the jaundice syndrome.
Materials and methods. Into the investigation 71 patients, suffering proximal obturation jaundice of tumoral genesis, were included. The patients were divided into three Groups: Group I - 26 patients, to whom external-internal suprapapillary cholangiostomy was done; Group II - 28 patients, in whom transcutaneous transhepatic antegrade endobiliary stenting was performed; Group III -17 patients, to whom endoscopic retrograde biliary stenting was accomplished.
Results. Technical success in all the Groups have constituted 100%; clinical one - in 94.0%: in Group I - 96.2%, in Group II - 89.3%, and in group III - 82.4% (p>0.05). In Group I general rate of morbidity was lesser, including cholangitis and pancreatitis. The duration of cholangitis was lesser as well. Cumulative survival were the highest in Group of patients, to whom external-internal suprapapillary cholangiostomy was performed (135 days at average), while the least one - in Group of the patients, in whom endoscopic retrograde biliary stenting was done (90,6 days). In Group of patients, to whom transcutaneous transhepatic antegrade endobiliary stenting was performed, this index have constitited 101.2 days.
Conclusion. In proximal strictures of biliary ducts of tumoral genesis on background of jaundice the priority method of palliative treatment must be external-internal suprapapillary cholangiostomy, while the second-line of surgical treatment must constitute transcutaneous transhepatic antegrade endobiliary stenting. Endoscopic retrograde biliary stenting owes the lowest priority.
Levels of cytokines in extended purulent peritonitis and methods of immunocorrection
Authors: Mammadova E. T.
Published: April 2021

Objective. Comparative studying of the cytokines secretion dynamics in extended purulent peritonitis in postoperative period on background of the standard basic therapy and its combination with cytokinotherapy.

Materials and methods. The levels of anti-inflammatory cytokines IL-2, IL-6, IL-8 and TNF-α in the blood of 97 patients, suffering extended purulent peritonitis of various genesis and various severity degree, were determined. Depending on kind of therapy conducted, the patients were divided into two Groups: the first one - 52 patients, obtaining standard basic therapy and the second - 45 patients, to whom cytokinotherapy was prescribed additionally to standard basic therapy.

Results. In the Group II patients the levels of IL-2, IL-6, IL-8 and TNF-α were raised significantly in reactive phase in 2.1 (p=0.035), 2.4 (p=0.002), 2.0 (p=0.004) and 3.5 (p=0.001) times, accordingly; toxic - in 5.1 (p<0.001), 5.6 (p<0.001), 2.4 (p<0.001) and 6.6 (p<0.001) times, accordingly; terminal - in 8.7 (p<0.001), 8.7 (p<0.001), 4.7 (p<0.001) and 8.6 (p<0.001) times, accordingly, comparing with control. On the tenth postoperative day the concentration of proinflammatory cytokines have lowered significantly in comparison to preoperative data.

Conclusion. In all the patients, owing various degrees of the extended purulent peritonitis severity, preoperatively a statistically significant raise of concentration of proinflammatory cytokines IL-2, IL-6, IL-8 and TNF-­α, comparing with indices in healthy persons, was noted. Targeted immunocorrection, using combined cytokinotherapy on background of complex basic treatment measures, normalizes a cytokinic balance.
Application of vascularized perforant flaps in the hand restoration in electro-thermic affections
Authors: Zhernov A. O. , Kovalenko O. M. , Zhernov O. A.
Published: April 2021

Objective. To improve the results of surgical treatment in patients with deep electric burns of the hand, using local vascularized flaps, based on perforant vessels.
Materials and methods. Analysis of the treatment results in 17 patients, suffering electric trauma of the hand was conducted, the defects plasty was performed, using local vascularized flaps, based on perforant vessels of the hand.
Results. In 17 patients 20 flaps were formed. Application of revascularization procedures have permitted to obtain good results in immediate period in 76.5% patients, and satisfactory - in 13.5% patients, in late follow-up period good results - in 88.2% patients, and satisfactory - in 11.8% patients.
Conclusion. The transplant, owing own blood circulation and locally vascularized flaps, based on perforant vessels, which are formed on non-injured parts of the hand, guarantee the blood supply restoration in the zone of electric thermic affection as well as the wound defect closing.
Surgical methods of treatment of hiatal hernias
Authors: Stasyshyn A. R. , Bochar V. T. , Pater Ya. Z. , Fedchyshyn N. R.
Published: April 2021

Surgical methods of treatment of hiatal hernias
The heart transplantation in early period after ending of a COVID-19-associated pneumonia
Authors: Usenko O. Yu. , Gabriyelyan A. V. , Mazur A. P. , Domanskyi T. M. , Beleyovych V. V. , Chaikovska S. M. , Romanova S. V. , Gurin P. V. , Khavin І. G. , Moshta S. S.
Published: April 2021

The heart transplantation in early period after ending of a COVID-19-associated pneumonia
Degloving injury of the distal aspect of the limb in a horse and preventing bone sequestrum formation using multiple, partial depth cortical fenestration
Authors: Koľvek Filip , Žert Zdeněk
Published: April 2021

Exposed or denuded bone is a common complication of wounds of the distal aspect of the limb. This clinical report describes the treatment of an extensive laceration of the right hindlimb of a 12-year-old Hungarian Warmblood Horse gelding, which was managed initially by application of hydrogel dressings to enhance autolytic debridement, subsequently, by cortical fenestration of the denuded cortical bone and by stimulating the production of granulation tissue to cover the exposed bone. An early radiographic sign of sequestrum formation (discrete changes in the outer cortex) was not seen after the injury. Six weeks later, the wound was completely covered with vascularized, healthy-appearing bed of granulation tissue, which was prepared for grafting using the punch technique. A reinforced bandage was applied for the following 7 weeks; the grafts were accepted by granulation tissue. The horse was discharged 20 weeks after admission and the owners were advised to maintain stall rest with hand walking for two weeks. Four years later the owner reported that the wound had completely healed with a good cosmetic outcome and the horse was being used in a carriage.