bluuebunny/crossref_metadata_2025 huggingface dataset:
A Model for Teaching English Translation in Universities Based on the Random Matrix Optimization Bell Translation Model
Authors: Xie Jiaojiao , Li Qiaohong
Published: June 2022

This paper adopts the random matrix optimization fusion of Bell’s translation model to conduct in-depth research and analysis on the teaching model of English translation in colleges and universities. Bell’s translation model theory explicates the mental model of the translation process to a certain extent based on psycholinguistic research results. Using the results of random matrix theory on the eigenvalues of the sample covariance matrix, the energy of each subspace is estimated, and the estimated energy is then used to construct the subspace-weighting matrix. The statistical properties of the sample covariance matrix eigenvectors were analyzed using the first-order perturbation approximation, and then asymptotic results from random matrix theory on the projection of the sample covariance matrix signal subspaces to the real signal parametrization were used to obtain the weighting matrix based on the random matrix eigenvectors. The analysis shows that the teacher can help students understand the teaching content and master the knowledge points by using guided meta-discoursal to indicate the logical relationships inherent in linguistic expressions and make the discourse transitions natural, coherent, and organized. The use of interactive meta-discoursal attracts students’ attention and treats them as participants in the discourse, making them feel a sense of belonging and satisfying their need for psychological belonging, which is beneficial to the students’ main position in the classroom. In teaching methods, there is a principle of comprehensible input, which is to provide students with a lot of interesting and understandable listening and reading input. In the translation classroom, the translation teachers code-switched infrequently and mainly used three types of code-switching: inter-sentence code-switching, intra-sentence code-switching, and additional code-switching to carry out translation teaching. Among them, intra-sentence code-switching accounts for 57.46%, inter-sentence code-switching accounts for 41.53%, and the least frequent is additional code-switching, accounting for 1.01%.
A Data-Secured Intelligent IoT System for Agricultural Environment Monitoring
Authors: Zhou Qing , Xiao Minghua , Lu Lei , Zeng Jun , He Wenting , Li Chao , Shi Yulun
Published: June 2022

Collecting environmental information of crop growth and dynamically adjusting agricultural production has been proved an effective way to improve the total agricultural yield. Agricultural IoT technology, which integrates the information sensing equipment, communication network, and information processing systems, can support such an intelligent manner in the agricultural environment. Traditional agricultural IoT could meet the service demand of small-scale agricultural production scenarios to a certain extent. However, the emerging application scenario of the agricultural environment is becoming more and more complicated, and the data nodes of the underlying access to IoT backend system are increasing in large number, while the upper-layer applications are requiring high quality of data service. Hence, the traditional architecture-based (i.e., centralised cloud computing) IoT systems suffer from the problems such as small network coverage, data security issue, and limited power supply time while attempting to provide high-quality services at the edge of the network. Emerging edge computing offers the opportunity to solve these issues. This paper builds an intelligent IoT system for agricultural environment monitoring by integrating edge computing and artificial intelligence. We conducted an experiment to validate the proposed system considering the reliability and usability. The experimental results prove the system’s reliability (e.g., data packet loss rate is less than 0.1%). The proposed system achieves the concurrency of 500TPS and the average response time of 300 ms, which meet the practical requirements in agricultural environment monitoring.
Design and Management of Microteaching Mode of Innovation and Entrepreneurship Education in Colleges and Universities Driven by Big Data
Authors: Zhu Huirong , Wang Qin
Published: June 2022

There have been few studies on the quality assessment at the meso- or microlevel in my country’s colleges and universities despite the fact that innovation and entrepreneurship (IAE) education is constantly progressing. A new assessment method based on big data is employed in this paper to investigate the design and management of microteaching modes for IAE education and to promote the development of IAE at these institutions while also enhancing the quality of innovative talent training. This paper addresses the urgent need to reform the evaluation system for IAE education. This paper has completed the following work: (1) this paper firstly analyzes the current situation of IAE education evaluation at home and abroad on the basis of literature research and summarizes the current theoretical thinking, methods, and shortcomings of IAE education evaluation. (2) Analyzing the present condition of IAE education assessment, relevant ANN technologies are introduced, and a suitable quality index system for IAE education is created. (3) With the use of big data, we were able to gather samples and data sets for the experiment, and then, we utilized the BP algorithm and the GA-BP algorithm to compare their accuracy in predicting the quality of IAE education, and the GA-BP algorithm has better performance.
[Retracted] Exploring the Independent Learning of Music Students in Higher Teacher Training Colleges in a Pluralistic Network Environment
Authors: Zhang Lei
Published: June 2022

As the main base for training teachers, normal colleges and universities can not only reserve a large number of talents for the construction of teachers but also help to improve the professional quality and teaching ability of teachers. Carrying out research on music education in normal colleges and universities can further meet the diversified needs of the current society for music talents and promote the improvement of art cultivation and cultural level of music students in normal colleges and universities. This paper discusses the preparation work of higher normal music colleges under the new curriculum standards from four aspects: “experience learning, independent learning, cooperative learning, and inquiry learning.” Later, through the method of questionnaire survey, starting from the survey of the independent learning motivation of 325 music education students, the independent learning situation of music education students under the network resources was analyzed, and the learning strategies were discussed from various aspects of students, teachers, and the school. By analyzing the current situation of music teaching in higher teacher training colleges from many aspects, and putting forward relevant suggestions according to the survey results, we hope to help the transformation of music teaching methods in the future and make contributions to the field of music teaching in China.
Research on Optimization of Adaptive Positioning and Routing Algorithm for Industrial Internet of Things Engineering Based on Improved Neural Network
Authors: Fang Xuanzheng , Yu Yang
Published: June 2022

The Internet of Things is one of the key technologies leading the development of modern industry. There is great uncertainty in the industrial production process, which causes great difficulties in the process of node perception and information transmission. Therefore, based on the improved neural network, this study designed the industrial Internet of Things engineering adaptive positioning and routing algorithm optimization methods. Based on the analysis of industrial IoT wireless sensor network node type, on the basis of exploring the advantages of back propagation neural network for the shortcomings of slow convergence speed and so on, we establish a discrete time Markov chain, determine its transition probability and the matrix, through interval differentiate, and calculate the estimate step error correction neural network. Then, training samples are selected to build an adaptive positioning model to obtain the absolute position of engineering nodes. Then, the shortest path constraints are set and independent variables are selected. After establishing the matrix form of the two-layer recursive neural network, the route traffic is updated by calculating the connection weight, so as to complete the routing optimization. The experimental results show that this method has high positioning accuracy and low overhead, and the optimized routing algorithm has a higher transmission success rate.
Identification of Key Genes in Severe Burns by Using Weighted Gene Coexpression Network Analysis
Authors: Guo ZhiHui , Zhang YuJiao , Ming ZhiGuo , Hao ZhenMing , Duan Peng
Published: June 2022

The aims of this work were to explore the use of weighted gene coexpression network analysis (WGCNA) for identifying the key genes in severe burns and to provide a reference for finding therapeutic targets for burn wounds. The GSE8056 dataset was selected from the gene expression database of the US National Center for Biotechnology Information for analysis, and a WGCNA network was constructed to screen differentially expressed genes (DEGs). Gene Ontology and pathway enrichment of DGEs were analyzed, and protein interaction network was constructed. A burn mouse model was constructed, and the burn tissue was taken to identify the expression levels of differentially expressed genes. The results showed that the optimal soft threshold for constructing the WGCNA network was 9. 10 coexpressed gene modules were identified, among which the green, brown, and gray modules had the largest number of burn-related genes. The DEGs were mainly related to immune cell activation, inflammatory response, and immune response, and they were enriched in PD-1/PD-L1, Toll-like receptor, p53, and nuclear factor-kappa B (NF-κB) signaling pathways. 5 DEGs were screened and identified, namely, Jun protooncogene (JUN), signal transducer and activator of transcription 1 (STAT1), BCL2 apoptosis regulator (Bcl2), matrix metallopeptidase 9 (MMP9), and Toll-like receptor 2 (TLR2). Compared with skin tissue of normal mouse, the messenger ribose nucleic acid (mRNA) and protein expression levels (PEL) of STAT1 and Bcl2 in burn tissue were greatly decreased, while those of JUN, MMP9, and TLR2 were increased obviously (

p
<
0.05

). In conclusion, STAT1, Bcl2, JUN, MMP9, and TLR2 can be potential biological targets for the treatment of severe burn wounds.
Application of Internet of Things Based on Wireless Sensor in Tunnel Construction Monitoring
Authors: Cao Jianfeng , Zhao Ruichuan , Hu Liqiang , Liang Qing , Tang Zhenhua
Published: June 2022

In order to solve the problems of insufficient frequency, time-consuming, and labor-consuming of monitoring and measurement in the process of tunnel construction, a tunnel construction monitoring and measurement technology based on Internet of Things is proposed in this paper. This method adopts the basic theory and technology of Internet of Things, analyzes the fit relationship between Internet of Things technology and tunnel construction, uses the comprehensive perception, reliable transmission, and intelligent auxiliary technology possessed by the existing Internet of Things technology system, and has been successfully applied to tunnel engineering. The experimental results show that the contact pressure between the surrounding rock and the initial support on the monitoring and measurement section in the tunnel is zero after the initial support shotcrete is applied. The contact pressure between the surrounding rock and the shotcrete layer at the right arch waist of the left tunnel is the smallest, and the stress in the whole change process is less than 10 kPa. The contact pressure between surrounding rock and shotcrete layer after excavation is divided into three stages. Conclusion. the tunnel construction monitoring and measurement technology based on Internet of Things technology fully realizes the intellectualization and informatization of the construction process, plays a scientific and effective monitoring and early warning role, and reduces the project cost of the whole project, which has a certain engineering value.
Enhancing the Stability and Safety of Vehicle When Steering by Using the Active Stabilizer Bar
Authors: Nguyen Duc Ngoc , Le Minh Phung , Nguyen Tuan Anh , Hoang Thang Binh , Tran Thi Thu Huong , Dang Ngoc Duyen
Published: June 2022

Centrifugal force is what causes the vehicle to roll over. This force is generated when the vehicle suddenly changes direction when moving at high speed. The solution of using a stabilizer bar is suggested to minimize this phenomenon. There are currently three types of stabilizer bars in use: mechanical stabilizer bars, hydraulic stabilizer bars, and electronic stabilizer bars. The content of this article is aimed at introducing and reviewing the characteristics of the stabilizer bar. Besides, two oscillation simulation models of vehicles equipped with stabilizer bars are also analysed in this article. Additionally, the characteristics of the control algorithms for the stabilizer bar are clearly analysed. The half-dynamics model is suitable for algorithms that need to use oscillatory state matrices such as SMC, LQR, and LQG. The spatial dynamics model is suitable for some algorithms such as PID, fuzzy, and neural. The roll angle of the vehicle has been significantly improved when the stabilizer bar is fitted. In general, the stability and safety of the vehicle can be guaranteed if the vehicle uses a stabilizer bar.
Prediction of Factors Associated with Abnormal Uterine Bleeding by Transvaginal Ultrasound Combined with Bleeding Pattern
Authors: Xu Yan , Xie Dan
Published: June 2022

In order to explore the ability of vaginal ultrasound combined with bleeding pattern to predict factors related to abnormal uterine bleeding (AUB), a total of 205 patients with abnormal uterine bleeding were selected as experimental subjects. According to the corresponding diagnostic criteria, patients were divided into the endometrial polyp group (56 cases), endometrial hyperplasia and canceration group (84 cases), and normal cycle endometrial group (65 cases). The efficiency of the method was determined by comparing the prediction efficiency of the single/joint model. The results showed that there were statistically significant differences in the body mass index, dysmenorrhea, endometrial thickness, diabetes, hypertension, and polycystic ovary syndrome among the three groups,

P
<
0.05

. The sensitivity, specificity, positive predictive value, negative predictive value, and Youden index of endometrial polyp diagnosis were 86.89%, 88.12%, 83.54%, 90.11%, and 0.74, respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and JordAn index in diagnosing endometrial hyperplasia and canceration were 96.71%, 98.40%, 96.54%, 98.24%, and 0.96, respectively. In summary, the body mass index, dysmenorrhea, endometrial thickness, diabetes, hypertension, and polycystic ovary syndrome were related factors, and the combination of vaginal ultrasound and bleeding pattern had a stronger predictive power for abnormal uterine bleeding.
Simulation of English Word Order Sorting Based on Semionline Model and Artificial Intelligence
Authors: Meng Zhange , Li Nan
Published: June 2022

To improve the word order ranking effect of English language retrieval, based on machine learning algorithms, this paper combines a semionline model to construct an artificial intelligence ranking model for English word order based on a semionline model and establishes a semisupervised ELM regression model. Moreover, this paper derives the mathematical model of semisupervised ELM in detail and uses FCM clustering to screen credible samples, ELM collaborative training to mark each other’s samples, and the marked samples to calculate the output weights of semisupervised ELM regression. In addition, based on continuous learning of OSELMR, this paper uses confidence evaluation to screen out credible unlabeled samples, OSELM collaborative training to mark the credible samples with each other, and credible unlabeled samples to calculate the output weight of SSOSELMR. Finally, this paper designs a control experiment to analyze the model algorithm, compares and counts the parameters, and draws a statistical graph. The research results show that the model constructed in this paper is effective.
COVID-19 Pandemic Data Modeling in Pakistan Using Time-Series SIR
Authors: Taimoor Muhammad , Ali Sajid , Shah Ismail , Muwanika Fred Roland
Published: June 2022

Pakistan is currently facing the fourth wave of the deadly coronavirus, which was first reported in Wuhan, China, in December 2019. This work utilizes the epidemiological models to analyze Pakistan’s COVID-19 data. The basic susceptible, infected, and recovered (SIR) model is studied assuming Bayesian and time-series SIR (tSIR) approaches. Many studies have been conducted from different perspectives, but to the best of our knowledge, no study is available using the SIR models for Pakistan. The coronavirus incubation period has been set to 14 days across the globe; however, this study noticed that the assumption of 14 days is not suitable for Pakistan’s data. Furthermore, on the basis of

R

0

, we infer that COVID-19 is not a pandemic in Pakistan, as it was in other nations, such as the United States, India, Brazil, and Italy, among others. We attribute this to the best strategy adopted by the Government of Pakistan to minimize the burden of COVID-19 cases in Pakistani hospitals. It is also noticed that the posterior-based SIR (pSIR) model with uniform prior to

R

0

and Poisson distribution (of log-likelihood) provides better results as compared to other distributions. From time-series SIR (tSIR), we observed that the value of the reporting rate

ρ

is less than 1 which means that cases are underreported.
Fetal and Neonatal Middle Cerebral Artery Hemodynamic Changes and Significance under Ultrasound Detection in Hypertensive Disorder Complicating Pregnancy Patients with Different Severities
Authors: Zhou Pei , Sun Yi , Tan Yongpan , An Yanru , Wang Xingxing , Wang Lufang
Published: June 2022

Colour Doppler ultrasound was applied for monitoring the hemodynamic parameters of fetal uterine artery (UtA), umbilical artery (UA), and middle cerebral artery (MCA) during pregnancy. In hypertension disease complicating pregnancy, these hemodynamic measures and their therapeutic applicability value were reviewed (HDCP). 120 singleton pregnant women were chosen, with 40 cases of mild preeclampsia (mild group), 40 cases of severe preeclampsia (severe group), and 40 normal control pregnant women (control group). The hemodynamic parameters of UtA, MCA, and UA were monitored in the three groups, including pulsatility index (PI), resistance index (RI), and the systolic/diastolic velocity (S/D). The parameters PI, RI, S/D, and venous catheter shunt rate (Qdv/Quv) of UtA and UA in the severe group were higher than those in the normal group and the mild group, showing the differences statistically significant (

P
<
0.05

). The PI, RI, and S/D of MCA in the severe group were lower than those in the normal group and the mild group (

P
<
0.05

). The changing trends of PI, RI, and S/D in the severe group were all first increased and then decreased in the early, middle, and later pregnancy (

P
<
0.05

). The area under the curve (AUC) was 0.98 in the receiver operating characteristic (ROC) curve created using a combination of hemodynamic measures and pregnancy outcomes, and the sensitivity and specificity for predicting bad outcomes were 94.7 percent and 96.4 percent, respectively. Colour Doppler ultrasound may accurately detect changes in the PI, RI, and S/D of UtA, MCA, and UA in pregnant women and serve as a reference for determining the intrauterine state of the fetuses and predicting bad pregnancy outcomes. In particular, the parameters in later pregnancy were higher worthy of diagnostic value for adverse pregnancy outcomes. The combination of various parameters could make an improvement of the diagnostic accuracy and provide a basis for guiding treatment as well as determining the optimal timing of delivery.
Design and Optimization of a Planar Biped Leg Based on Direct Drive Linear Actuators
Authors: Langard M. , Lucidarme Ph. , Delanoue N. , Guyonneau R. , Mercier F. , Chevallereau C. , Wenger Ph. , Aoustin Y.
Published: June 2022

The choice of actuation when designing a bipedal robot is an important matter, as it impacts its capacities and its control. In these aspects, electric direct-drive (DD) linear motors are interesting candidates. Indeed, they can reproduce the human muscle system by using monoarticular and bi-articular motors and offer a natural backdrivability for impact mitigation. However, motor efficiency depends on their elongation and their attachment points. The ROBIBIO (RObot humanoïde BI-articulaire BIO-inspiré) project aims to design and build a planar bipedal robot using electric direct-drive linear motors for the actuation. To do so, a simulator was developed to evaluate multiple human-like bipedal robot architectures over a set of motion-captured movements. Furthermore, a numerical optimization was done to find the best motor placement for each architecture.
Oral Cancer Incidence, Mortality, and Mortality‐to‐Incidence Ratio Are Associated with Human Development Index in China, 1990–2019
Authors: Xie Long , Shang Zheng-Jun
Published: June 2022

The burden of oral cancer (OC) is closely related to economic development. We aimed to evaluate the burden of OC at different stages of economic development in China in terms of incidence, mortality, and mortality‐to‐incidence ratio (MIR) from 1990 to 2019. Data on cancer in China from 1990 to 2019 were obtained from the Global Burden of Disease 2019. Based on human development index (HDI), Chinese economic development was divided into three stages: low, medium, and high HDI stages. Mann–Whitney U‐test was used to evaluate the differences in age‐standardised incidence rates (ASIR), age‐standardised mortality rates (ASMR), and MIR at various stages of HDI. Correlation and regression tests were conducted to examine the association amongst ASIR, ASMR, MIR, and HDI in OC. The estimated annual percentage changes (EAPCs) were calculated to assess the trend of ASIR, ASMR, and MIR. Significant differences were observed in terms of ASIR, ASMR, and MIR between groups (P < 0.001). The values of both sexes in the low HDI stage were lower than those of the medium and high HDI stages, except for MIR, in which the low HDI stage was the highest (P < 0.05). ASIR and ASMR of OC in males at the medium HDI stage showed the fastest growth rate with EAPC values of 5.64 (95% confidence interval, 95% CI, 5.20 to 6.08) and 4.42 (95% CI, 4.01 to 4.82), respectively. A strong positive correlation exists between HDI and ASIR (r = 0.96) and ASMR (r = 0.91) in both sexes from 1990 to 2019. During the high HDI stage, the ASIR and ASMR of OC were at a high level, but the ASIR halted the uptrend trend and ASMR showed a decreasing trend. Therefore, the HDI index has been positively correlated with the ASIR and ASMR of OC in China in the past 30 years, but this relationship may not be sustained as the economy develops. The health department should continue to allocate additional resources for the prevention and treatment of OC.
Multiorientation Simultaneous Computation of Back-Projection CT Image Reconstruction Algorithm in Staging Diagnosis of Bladder Cancer
Authors: Hu Kaiyan , Zhu Jianping , Li Pei , Ying Lili
Published: June 2022

The objective of this research was to investigate the multidirectional synchronous calculation of the back-projection computed tomography (CT) image reconstruction algorithm (MSBP) in the staging diagnosis of bladder cancer. Sixty patients with bladder cancer admitted to the hospital were selected for enhanced CT scanning, all of which were randomly divided into control group (

n
=
30

) and study group (

n
=
30

). The filtered back-projection (FBP) algorithm was employed to reconstruct the scanned image, and the MSBP was additionally applied to the images of the study group. Fringe artifact (SA), overall mass (OQ), effective radiation dose (ED), CT dose-exponential volume (CTDI), and dose-length product (DLP) of the two groups of images were compared and analyzed. The results showed that the total time of the traditional algorithm was 5.473 s, and the total time of MSBP combined with FBP algorithm was 2.832 s, which was significantly higher than that of the traditional algorithm (

P
<
0.05

). CT scan bladder cancer staging results of all patients were compared with surgical pathological staging results, and the results were evaluated according to the coincidence rate. SA in the study group was lower than that in the control group (

P
<
0.05

), and OQ was not statistically significant. The ED of the study group was significantly lower than that of the control group by 33%. The coincidence rate of postoperative pathological staging results and CT staging results was 96%, and T1, T2a, and T4 coincidence rate was 100%, The coincidence rates of T2b, T3a, and T3b were 90%, 83.3%, and 66.67%, respectively. In summary, using MSBP method combined with FBP algorithm can improve OQ while reducing ED of patients. The introduction of MSBP into CT reconstruction image simplified the pixel location operation of projection calculation, showing an important application value in preoperative staging diagnosis of bladder cancer.
Effect of Different General Anesthesia Methods on the Prognosis of Patients with Breast Cancer after Resection: A Systematic Review and Meta-analysis
Authors: Lv Rui , Zhang Chunli , Huang Yuyuan , Xiao Peng
Published: June 2022

Background. The effect of total intravenous anesthesia (TIVA) and inhalation anesthesia (IA) on the prognosis of breast cancer patients has been controversial. The study is aimed at exploring the effects of different anesthesia methods on the postoperative prognosis of breast cancer patients. Methods. Literature retrieval was conducted in PubMed, EMBASE, MEDLINE, Embase, CENTRAL, and CNKI databases. The literature topic was to compare the effects of TIVA and IA on the prognosis of patients undergoing breast cancer resection. Two researchers extracted data from the literature independently. This study included randomized controlled trials that evaluated for risk of bias according to the “Risk assessment Tool for Bias in Randomized Trials” in the Cochrane Manual. The Newcastle-Ottawa Scale (NOS) was used to assess the risk of bias in observational studies. The chi-square test was used for the heterogeneity test. Publication bias was assessed using funnel plots and Egger’s test. If heterogeneity existed between literature, subgroup analysis and sensitivity analysis were used to explore the source of heterogeneity. Sensitivity analysis was performed by excluding low-quality and different-effect models. Data were statistically analyzed using the Cochrane software RevMan 5.3. Hazard ratio (HR) and 95% confidence interval (CI) were used for statistical description. Results. Seven literatures were selected for meta-analysis. There were 9781 patients, 3736 (38.20%) receiving TIVA and 6045 (61.80%) receiving inhalation anesthesia. There was no significant difference in overall survival (OS) between TIVA and IA breast cancer patients (

HR
=
1.05

, 95% CI (0.91, 1.22),

Z
=
0.70

,

P
=
0.49

). There was no difference in the literature (

χ

2

=
6.82

,

P
=
0.34

,

I

2

=
12
%

), and there was no obvious publication bias. There was no significant difference in recurrence-free survival (RFS) between TIVA and IA patients (

HR
=
0.95

, 95% CI (0.79, 1.13),

Z
=
0.61

,

P
=
0.54

). There was no heterogeneity in the literature (

χ

2

=
5.23

,

P
=
0.52

,

I

2

=
0
%

), and there was no significant publication bias. Conclusion. There is no significant difference in OS and RFS between TIVA and IA patients during breast cancer resection. The prognostic effects of TIVA and IA were similar.
[Retracted] Consumption Pattern and Mental Health of Employees Based on Big Data Analysis
Authors: Su Teng
Published: June 2022

With the development of big data concept and technology, big data has an important impact on human development. This paper studies the relationship between the consumption pattern and mental health of enterprise employees under the normalization of epidemic prevention and control. Starting from the consumption structure and behavior of enterprise employees, it defines the meaning of enterprise employees’ consumption and the connotation of enterprise employees’ health psychology and analyzes the relationship between consumption behavior and consumption psychology and the elements of enterprise employees’ health psychology. Based on the change of employees’ income structure and consumption patterns, this paper speculates the relationship between employees’ consumption patterns and mental health, analyzes the correlation between employees’ consumption patterns and mental health through a questionnaire survey, and calculates the Correlation Clustering statistical results. It plays an important role in building a good enterprise staff consumption culture under the normalization of epidemic prevention and control and effectively realizes the significance of purifying the social consumption environment.
Postoperative Adjuvant Chemoradiotherapy on the Survival of Stage III Gastric Cancer
Authors: Li Chao , Shao Shoupeng , Sun Yue , Shen Fujun , Wang Meijuan , Wang Hongsheng , Wang Chunbin
Published: June 2022

Objective. Although adjuvant therapy has been shown to be beneficial in gastric cancer, the use of adjuvant chemoradiotherapy remains controversial. This paper investigated the effects of postoperative adjuvant chemoradiotherapy on the survival of patients with stage III gastric cancer. Methods. In total, the data of 72 stage III gastric cancer patients treated at our hospital from January 2014 to December 2019 were retrieved and assessed. They were categorized into a chemotherapy group (CT group) and a radiochemotherapy group (RCT group) according to their given treatment regimens. A 3-year follow-up was conducted to record their incidence of disease-free survival (DFS), overall survival (OS), and adverse events. Results. For the CT and RCT groups, DFS was 86.4% and 92.6% in the first year, decreasing to 55.1% and 73.7% in the second year, and 41.3% and 69.1% in the third year. There was no significant difference in DFS between the two groups during the three-year follow-up. Additionally, for the CT and RCT groups, their respective 1-year, 2-year, and 3-year OS were 95.6% and 96.3%, 75.1% and 87.9%, and 50.3% and 74.2%, indicating that the OS of patients in the RCT group was significantly higher than that in the CT group during 3 years of follow-up. Further, no significant difference in the incidence of adverse events was found between the two treatment groups. Conclusions. Collectively, adjuvant radiochemotherapy after radical gastrectomy for stage III gastric cancer was associated with better survival outcomes than chemotherapy, without increase in adverse events.
Design and Evaluation of a Cyanate Ester Containing Oxaspirocyclic Structure for Electronic Packaging
Authors: Lei Xuefeng , Ma Junxian , Lin Kaiwen , Wang Yuehui , Huang Zengfang
Published: June 2022

A type of pentaerythritol cinnamaldehyde bisphenol dicyanate ester (PCBDCy) containing oxaspirocyclic structure is well designed and synthesized in three steps from cinnamaldehyde, pentaerythritol, phenol, and cyanogen bromide. The products in each step are characterized by elemental analysis, Fourier transform infrared (FT-IR) spectroscopy, and 1H NMR spectroscopy. The mechanical properties, dielectric properties, thermostability, and water absorption of PCBDCy are investigated in detail. The results show that compared with bisphenol A dicyanate (BADCy), the PCBDCy possesses more excellent comprehensive properties. The bending strength and flexural strength are increased by 10.71% and 47.62%, respectively. The fracture toughness

K

IC

and

G

IC

are 1.5 times and 2 times of BADCy, respectively, indicating that its mechanical properties have been considerably improved. The dynamic mechanical curves indicates that the degree of phase separation is significantly reduced, the tan (δ) value representing the flexible phase is obviously shifted to the high temperature region, and the initial decomposition temperature was 12°C higher than that of BADCy, indicating that the material has excellent thermal stability. In addition, the dielectric constant and loss tangent are almost as same as those of BADCy, maintaining good dielectric properties. The water absorption rate has increased to

1.03
±
0.03
%

. Compared with BADCy, its comprehensive performance is more suitable for the field of microelectronic packaging.
[Retracted] Effect of Ruanjian Xiaoying Granules on Hashimoto Rats with Depression of Liver and Deficiency of Spleen and Effect on Intestinal Microflora
Authors: Dong Tianjiao , Zhang Lan
Published: June 2022

In order to investigate the effect of Ruanjian Xiaoying Granule, experiments were conducted on the intestinal flora of rats with liver depression and spleen deficiency. 48 SPF grade rats are used as the object, and 12 rats are randomly selected as the normal control group. The Hashimoto rat model of liver depression and spleen deficiency type by drug intervention is constructed by the remaining rats. They are randomly divided into three groups: the model group, the traditional Chinese medicine group, and the Jinshuibao group. The normal group and model group are given 2 ml of distilled water twice a day, and the traditional Chinese medicine group is given the Ruanjian Xiaoying granule group (12.96 g/kg/day) twice a day. The Jinshuibao capsule is dissolved in water and given orally at a dose of 0.45 g/kg/day twice a day. After 12 weeks of intervention, the effect is evaluated, and the levels of serum TGAb, TPOAb, and bacterial diversity are compared. Experimental results show that Ruanjian Xiaoying granules can promote the regulation of flora levels in Hashimoto rats with liver depression and spleen deficiency.
Clinical Application of Noninflating Video-Endoscopic Inguinal Lymph Node Dissection
Authors: Chen Jinhu , Yan Lei , Luo Guangyue , Fang Weihua , Liang Chaozhao
Published: June 2022

Objective. To assess the safety and efficacy of the application of self-made non-inflating suspension technique in video endoscopic inguinal lymph node dissection (ILND). Methods. We collected 8 patients with penile carcinoma who underwent noninflating video-endoscopic ILND in the Department of Urology, the First Affiliated Hospital of Anhui Medical University, from May 2019 to March 2021. Then, surgical duration, blood loss, drainage tube indwelling time, hospital stay, number of dissected lymph nodes, and complications in the patients were analyzed. Results. All patients (

n
=
8

) finished the surgery successfully, with an average surgical duration of 125 (105-145) minutes, blood loss of 41 (25-50) mL, indwelling time of drainage tube of 7 (5-12) days, and a hospital stay of 14.8 (9-21) days. Additionally, 8.8 (3-14) left side and 7.3 (2-17) right side lymph nodes were dissected on average. Complications occurred in 3 patients during a perioperative period. The patients were followed up for 6-24 months, and none suffered recurrence or metastasis. Conclusion. The efficacy of noninflating video-endoscopic ILND is good. Patients who have undergone the surgery not only have few postoperative complications but also have a good prognosis, suggesting the safety and availability of the clinical application.
[Retracted] A Comparison of Finite Difference and Finite Volume Methods with Numerical Simulations: Burgers Equation Model
Authors: Ali Ali Hasan , Jaber Ahmed Shawki , Yaseen Mustafa T. , Rasheed Mohammed , Bazighifan Omer , Nofal Taher A.
Published: June 2022

In this paper, we present an intensive investigation of the finite volume method (FVM) compared to the finite difference methods (FDMs). In order to show the main difference in the way of approaching the solution, we take the Burgers equation and the Buckley–Leverett equation as examples to simulate the previously mentioned methods. On the one hand, we simulate the results of the finite difference methods using the schemes of Lax–Friedrichs and Lax–Wendroff. On the other hand, we apply Godunov’s scheme to simulate the results of the finite volume method. Moreover, we show how starting with a variational formulation of the problem, the finite element technique provides piecewise formulations of functions defined by a collection of grid data points, while the finite difference technique begins with a differential formulation of the problem and continues to discretize the derivatives. Finally, some graphical and numerical comparisons are provided to illustrate and corroborate the differences between these two main methods.
Characteristics of Pharmacists’ Interventions Related to Proton-Pump Inhibitors in French Hospitals: An Observational Study
Authors: Yailian AL , Huet E. , Charpiat B. , Conort O. , Juste M. , Roubille R. , Bourdelin M. , Gravoulet J. , Mongaret C. , Vermorel C. , Bedouch P. , Janoly-Duménil A.
Published: June 2022

Background/Objective. Overprescribing proton-pump inhibitors (PPIs) has become the norm worldwide and represents a global health issue with tangible clinical and economic consequences. At national level, we do not know how pharmacists are contributing to this issue. Thus, the study focused on analyzing drug-related problems (DRPs) pertaining to PPI prescriptions, detected during the medication order review process in French hospitals, and associated pharmacist interventions (PIs). Methods. The study was based on a retrospective analysis of pharmacist interventions for DRPs detected during the medication order review and documented into the French Act-IP© database over a 12-year period. DRPs and PIs were analyzed, and independent factors of physician acceptance were assessed via multiple logistic regression. Results. Out of the 620,620 PIs registered, 29,694 targeted a PPI (4.8%). PPI’s DRPs were mostly related to the prescription of a “drug not available at the hospital” (26.1%) and a “drug use without indication” (18.3%); PIs were mostly “drug switch” (35.9%) and “drug discontinuation” (26.1%). In all, 18,919 PIs were accepted by physicians (63.7%). Acceptance was significantly associated with patient age: less accepted for the 18–75 years group (OR = 0.59, 95 CI [0.46–0.76]), and the >75 years group (OR = 0.57, 95 CI [0.44–0.73]) vs. <18 years group; for the type of DRP, “drug use without indication” was the less accepted (OR = 0.73, 95 CI [0.63–0.85]); for the type of PI, “dose adjustment” was the less accepted (OR = 0.32, 95 CI [0.23–0.45]). Conclusion. Pharmacists contribute to preventing DRPs associated with PPI prescriptions during the medication order review process. Moreover, they often detect PPIs used without indication and they propose drug discontinuation, which contributes to the PPI deprescribing process. PIs should be further developed in the future to reduce PPI overprescription.
Growth and Development in Preterm Infants and Maternal Parenting Stress after WeChat-Based Extended Care
Authors: Zheng Lan , Zhu Zengxia
Published: June 2022

Objective. WeChat-based extended care has been widely applied in clinical practice such as preoperative assistance in children with congenital heart disease and children with ventricular septal defect. In this study, we aimed to explore the impacts of WeChat-based extended care on the growth and development of preterm infants (PIs) and the nursing satisfaction of their family members. Methods. From June 2019 to August 2021, 85 PIs and their mothers were selected as the research participants. Among them, 46 pairs receiving WeChat-based extended care were served as the WeChat group, and 39 pairs receiving routine extended care were taken as the control group. After 6 months of intervention, the two groups of PIs were compared in terms of physical development, IQ, and neurological and gastrointestinal functions. For mothers, their psychological states were assessed after intervention using the self-rating anxiety/depression scale (SAS/SDS), and the nursing satisfaction was counted. Results. After nursing intervention, better physical and IQ development of PIs were observed in the WeChat group compared with the control group (

P
<
0.05

). The WeChat group also had notably reduced level of neuron-specific enolase (NSE) and s100β protein related to nerve function than that in the control group and exhibited significant higher levels of serum gastrin (GAS) and motilin (MTL) associated with gastrointestinal function (

P
<
0.05

). Besides, the WeChat group presented lower SAS and SDS scores and higher nursing satisfaction than the control group in delivery women (

P
<
0.05

). Conclusion. WeChat-based extended care can effectively improve the growth and development and various physical functions of PIs. At the same time, it is helpful to improve maternal psychological states and nursing satisfaction of delivery women, which is worth of clinical application.
RNA Helicase DDX24 Stabilizes LAMB1 to Promote Hepatocellular Carcinoma Progression
Authors: Liu Tianze , Gan Hairun , He Simeng , Deng Jia , Hu Xinyan , Li Luting , Cai Li , He Jianzhong , Long Haoyu , Cai Jianxun , Li Hanjie , Zhang Qianqian , Wang Lijie , Chen Fangbin , Chen Yuming , Zhang Haopei , Li Jian , Yang Lukun , Liu Ye , Yang Jian-Hua , Kuang Dong-Ming , Pang Pengfei , He Huanhuan , Shan Hong
Published: June 2022

Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies. Elucidating the underlying mechanisms of this disease could provide new therapeutic strategies for treating HCC. Here, we identified a novel role of DEAD-box helicase 24 (DDX24), a member of the DEAD-box protein family, in promoting HCC progression. DDX24 levels were significantly elevated in HCC tissues and were associated with poor prognosis of HCC. Overexpression of DDX24 promoted HCC migration and proliferation in vitro and in vivo, whereas suppression of DDX24 inhibited both functions. Mechanistically, DDX24 bound the mRNA618–624nt of laminin subunit beta 1 (LAMB1) and increased its stability in a manner dependent upon the interaction between nucleolin and the C-terminal region of DDX24. Moreover, regulatory factor X8 (RFX8) was identified as a DDX24 promoter-binding protein that transcriptionally upregulated DDX24 expression. Collectively, these findings demonstrate that the RFX8/DDX24/LAMB1 axis promotes HCC progression, providing potential therapeutic targets for HCC.

Significance:

The identification of a tumor-promoting role of DDX24 and the elucidation of the underlying regulatory mechanism provide potential prognostic indicators and therapeutic approaches to help improve the outcome of patients with hepatocellular carcinoma.
Assessment of the Microbiological Quality and Safety in Takeaway Sushi Meals in Portugal
Authors: Alegria Sandy J.C. , Santos Maria Isabel S. , Furtado Rosália M.S. , Correia Cristina Belo , Lima Ana Isabel G. , Pedroso Laurentina R. , Ramos Sónia Catarina da Silva
Published: June 2022

Being a food product that contains perishable ingredients and involves a significant degree of manual handling during preparation, sushi is regarded as a potentially hazardous food, which may lead to foodborne disease outbreaks. In Portugal, consumption of takeaway sushi meals has strongly increased throughout the past few years; however, there is limited information regarding its compliance with food quality standards. Under this context, the present study aimed to evaluate the microbiological quality and safety of take-away ready-to-eat sushi meals in Lisbon, Portugal. Sixty-two samples were collected from different origins (restaurant and hypermarket), and each sample was tested for aerobic mesophilic microorganisms, Enterobacteriaceae, Escherichia coli, positive coagulase Staphylococci, presumptive Bacillus cereus count, as for detection of pathogenic microorganisms, such as Salmonella spp., Listeria monocytogenes and Vibrio parahaemolyticus, V. cholerae and V. vulnificus. Results revealed that 48.4% (30/62) were deemed unsatisfactory, 35.5% (22/62) were classified as borderline and only 16.1% (10/62) were considered satisfactory. Even though we did not detect the incidence of potentially pathogenic microorganisms in sushi, the presence of B. cereus and coagulase-positive Staphylococci was detected at unsatisfactory levels. Furthermore, significant differences between the place of origin (restaurant vs. hypermarket) and type of fish were also observed. Overall, the high number of samples classified with a level of microbiological quality “unsatisfactory” and “borderline” highlights the need to review good hygiene practices, as well as the quality of the raw materials used, to obtain a final product with a satisfactory quality and safety level.
Interaction Competencies with Children – Entwicklung und Wirkmechanismen einer präventiven Intervention für Lehrkräfte im Kontext gesellschaftlich akzeptierter Gewalt
Authors: Kirika Anette , Hecker Tobias
Published: June 2022

Gewalt gegen Kinder ist ein globales Problem und hat massive negative individuelle und gesellschaftliche Folgen. In vielen Ländern ist Gewalt in der Erziehung gesellschaftlich akzeptiert und weit verbreitet. Gewalt gegen Kinder hat vielfältige gesellschaftliche und individuelle Ursachen sowie aufrechterhaltende Faktoren. Auch in Schulen sind Kinder andauernder Gewalt ausgesetzt, was für die Notwendigkeit präventiver schul-basierter Programme spricht. Die Zielgruppe präventiver Programme sollten vor allem die Personen sein, von denen die Gewalt ausgeht – in diesem Kontext: Lehrer/innen. Die ursächlichen Faktoren sollten möglichst umfassend adressiert werden, wobei der oftmals ressourcenarme Kontext berücksichtigt werden muss. In diesem Übersichtsartikel wird die präventive Intervention Interaction Competencies with Children – for Teachers beschrieben und deren Wirkmechanismen diskutiert. Die Intervention ist ein 5,5-tägiges Training für Lehrer/innen in Gesellschaften, in denen Gewalt als Disziplinierungsmaßnahme akzeptiert ist. Ziel der Intervention ist eine Verhaltensveränderung der Lehrer/innen. Ein zentraler Wirkfaktor ist die Dynamik der Intervention, durch die zunächst eine Verände­rungsbereitschaft, dann eine Handlungskompetenz und Handlungsmotivation bewirkt wird. Des Weiteren wirkt die Intervention auf verschiedenen Ebenen und adressiert normative Aspekte, die sowohl das System Schule betreffen, als auch individuelle Faktoren. Wie die verschiedenen Metho­den und Themen auf individueller und schulischer Ebene wirken und miteinander interagieren, sollte zukünftig durch eine Evaluation des Veränderungsprozesses beantwortet werden.