bluuebunny/crossref_metadata_2025 huggingface dataset:
Mental vocabulary in the text the Khakas heroic tale Albynchy
Authors:   Khakas Scientific Research Institute of Language, Literature and History, Maria CHERTYKOVA
Published: April 2024

Our research is devoted to the identification and description of one of the fragments of the folklore-linguistic picture of the world – the semantic field of mental vocabulary based on the material of the Khakas heroic legend Albynchy. The interest in this linguistic representation of the characters' image stems from the principle of the anthropocentric paradigm, which represents the study of the inner world of a person, in particular, their psychological and mental functions. We understand a mental vocabulary as lexemes that not only name the process, the state of the subject, but contain elements of its description in their semantics and indicate the ethnic specifics of perception, understanding, cognition of the surrounding reality by an individual linguistic personality or the ethnolinguistic community as a whole. The purpose of the study is to identify and describe the semantic and functional structures of a mental vocabulary based on the material of the specified work of oral folk art. The tasks set to achieve this goal are related to the anthropocentric paradigm, i.e. the issues of revealing the human phenomenon through language. The relevance of the research is due to the insufficiency of research on the lexical system of the language of the Khakas heroic tales and the need to develop their linguistic and folklore paradigm as an independent scientific direction. The novelty of the research lies in the fact that mental vocabulary based on folklore material becomes the subject of special research for the first time. Based on the material of the Khakas heroic tale Albynchy the field of mental vocabulary turned out to be few. These include two basic verbs (сағын- ‘to think’, пiл- ‘to know’); verbal synonymous constructions; nouns – synonyms with the general meaning “mind, thought, reason” (ис, ағыл, сағыс), one cliched expression (ис ирт-, ағыл ас- ‘reason to pass by, lose your mind’), the phraseology of сағыс кiр- ‘the mind to enter’, describing the processes of mental activity and mental states of the characters. The study revealed that the semantic structures of these means of expressing mentality differ significantly from the contents of common-language dictionary variants, since the system of traditional folklore texts primarily reflect the ideological orientations and attitudes of the ethnic group. The conceptual basis of the set of mental representations is the categorical polarity of assessments: positive and negative in the absence of a neutral one. We see the prospects for the study of the language of heroic tales in deeper and more thorough developments of both individual lexical groupings and conceptual spheres, which contribute to the development of the Turkic interdisciplinary directions “folklore-linguistic picture of the world” and “linguofoloristics”.
The technique of repetition in Altai heroic tales
Authors:   S. S. Surazakov Research Institute of Altaistics, Surlai ABYSOVA
Published: April 2024

Altai heroic tales are unique monuments of the people’s epic heritage. They act as a cultural code that preserved the originality of the ethnic worldview, traditions of the people, as well as the peculiarities of their poetic language. At the same time, the Altai epic has much in common and peculiar in comparison with the epics of other Turkic-speaking peoples. The study of the epic style originality is special interest for folkloristics. The relevance of this study is determined by the insufficient study of style features of the Altai people’s heroic tales. The scholarly novelty of the work consists in the fact that it is the first to study the types of repetition as one of the stylistic phenomena of the Altai epic. The purpose of this research is to study repetition as a stylistic phenomenon of folk poetics. The sources for the study were the heroic tales published in the series “Altai Bogatyrs”. An important criterion for selecting sources for the study was the observation of this phenomenon in authentic texts, where the features of the narrator’s living language are preserved to a greater extent. The study is based on the analysis of Altai heroic tales from different narrators and other folklore sources. The descriptive method, methods of comparison and generalization were also used in the work. As a result of the study, the types of repetitions found in the Altai epic were identified and described; their main functions were defined. It is established that repetition in folklore text is an important and multidimensional phenomenon. In heroic tales it is manifested at different levels. Repetitions of individual words and word combinations, phrases and whole episodes are distinguished. According to the frequency of use, there are twofold, threefold and more repetitions. Repetitions occur within a line, at the beginning, end or at the junction of poetic lines, forming such stylistic figures as anaphora, epiphora and epanaphora. Each type of repetition fulfills a certain function in the text. The study has shown that the functioning of repetitions in heroic tales differs in the activity of their use by narrators.
« Mettre au monde le monde ».. Sur la relation entre sémiotique de la production et production sémiotique
Authors: Valle Andrea
Published: April 2024

Le concept de production sémiotique admet au moins une double déclinaison. En premier lieu, et historiquement, il concerne la praxis responsable de la réalisation d’objets qui rentrent dans le domaine de la sémiotique. En d’autres termes, c’est en fonction de la reconnaissance du caractère sémiotique du produit que l’on étudie le parcours historique qui en est à l’origine ; parcours qui, en fonction de cette origine, est pour cela même d’intérêt sémiotique, en tant que « production ». Par exemple, il s’agit de partir d’une œuvre et, une fois qu’elle a assumé le statut de « texte », d’y étudier le travail de l’artiste. En deuxième lieu, on entend par « production » un ensemble d’opérations qui président à la construction sémiotique d’un objet. Or, ce dernier ensemble d’opérations devrait recevoir une formalisation sémiotique qui rende compte du processus de production qui préside à l’achèvement de l’état du produit (et qui est déjà entièrement interne à l’ordre du sémiotique). Si le produit dont il est question est le texte-énoncé (et d’ailleurs cela ne pourrait pas être autrement), alors une théorie de la production coïncide pour l’essentiel avec une théorie de l’énonciation – c’est d’ailleurs ce que Greimas et Courtés remarquaient dans le Dictionnaire, à l’entrée « production ». A partir de cette double déclinaison, une duplicité intéressante découle : un même objet-texte peut donner accès à deux théories de la production, l’une à vocation « exogonique » et l’autre à vocation « endogonique ». La première permet la convocation des pratiques de production historiquement attestées (et par là même, l’étude empirique des pratiques elles-mêmes) ; la seconde conduit à la définition formelle du concept de praxis en sémiotique (à travers un travail fondamental sur la praxis énonciative, travail qui est bien loin d’être terminé). Toutefois, ce hiatus constitue aussi la possibilité d’une connexion. La discussion générale sur le concept de « pratique » demande donc un « nouement » : il sera question de garder ensemble pratiques historiques et modèles sémiotiques, afin d’en évaluer les relations possibles. Pour l’instant, et en exploration, on peut vérifier cet ensemble de problèmes à partir de deux exemples relevants. Le premier est le cas de la notation musicale contemporaine et des phénomènes concernés, entre composition, notation et exécution. Le deuxième exemple sera avancé à partir de quelques compositions d’Alighiero Boetti, dans lesquelles la relation entre projet et réalisation semble suivre des parcours analogues à ceux de la notation musicale.
Faire un point
Authors: Beyaert-Geslin Anne
Published: April 2024

« Faire » un énoncé artistique, c’est toujours, au départ « faire un point », fût-il grain du pigment archaïque, point de la peinture (Kandinsky), point-écran de la vidéo (Kuntzel) ou pixel de l’écran informatique. Ce grain-point qui détermine la genèse du visuel procède de pratiques différentes selon qu’il manifeste une intentionnalité rituelle (Leroi-Gourhan) ou esthétique. Il suggère également des rapports distincts à l’énonciation et plusieurs définitions épistémologiques : le grain est posé ; avec un liant, il devient peinture et se dispose au geste du peintre tandis que le pixel, échangeur entre l’image et le calcul mathématique, se « fait » à l’écran.Qui « fait » ? (quelle instance) et que « fait »-il (poser, tracer, composer à l’écran…) ? On voit aussi que le lien intime qui relie, par-delà les âges, le pigment de la Préhistoire au pixel d’aujourd’hui, sous-tend des modèles génératifs et des régimes sémiotiques distincts (l’alternative représentation/simulation de Couchot). La différence porte de même sur les rapports à la perception, l’effet « pelliculaire » du pixel renouant avec celui du pigment mais s’opposant résolument aux profondeurs de la peinture. Pourtant, en dépit de ces différences, une ressemblance essentielle subsiste qui tient au caractère veridictoire du grain-point. En effet, c’est toujours ce grain-point qui, devenu ligne (Kandinsky) et figure, déclare l’image comme telle, qu’il trahisse sa fiction au travers du flou ou du carré insistant du pixel-art. Par cet effet métadiscursif, il révèle que l’image a été faite et relève bien d’un « faire » poïétique séparé de l’être, quand bien même elle paraît-être. En ce sens, la « vérité » des images tiendrait moins à la collusion du paraître et de l’être que consacre le carré de la véridiction qu’à une déhiscence fondamentale entre l’être et le « faire ».
Pierre Bergounioux et le paysage corrézien
Authors: Marcheix Daniel
Published: April 2024

Le paysage corrézien évoqué par de nombreux textes « méditatifs » de Pierre Bergounioux est le cadre d’une expérience sensible particulièrement houleuse. L’activité perceptive y est violemment contrariée par l’hostilité désordonnée et l’instabilité d’un espace clos qui impose au personnage-narrateur une présence vide, quasi pathologique, comme si le monde intérieur était contaminé par l’antagonisme généralisé qui affecte le réel. Dans ce désastre esthésique, seuls le rêve et le cogito cartésien permettent de redonner à la perception une intentionnalité, de rendre le sensible intelligible. Ainsi s’esquisse une nouvelle forme d’immanence, attentive aux « fastes du dehors » que s’emploie à magnifier une écriture poétique ancrée dans la matière même.
Le paysage dessiné : un espace de projection identitaire
Authors: Darrault-Harris Ivan , Grubits Sonia
Published: April 2024

L’analyse psychosémiotique de dessins de paysage réalisés par des adolescents guarani-kaïowa du Brésil met en lumière leurs difficultés de quête d’identité, difficultés dues à une nécessaire transculturalité, qu’ils décident de rester dans la réserve ou de la quitter. En effet, il faut remettre en cause la cosmogonie traditionnelle et sa répartition du Monde en trois espaces organisés verticalement (organisation projetable, aussi, horizontalement). De manière étonnante, cette tripartition du Monde, devenus impossible à soutenir (à cause du confinement dans la réserve), se convertit, dans certains dessins, en un détriplement du ‘point de vue », manière de maintenir, en désespoir de cause, la structure ternaire fondamentale.D’autre part, l’analyse de ce processus identitaire plein d’embûches «éclaire le problème de l’étiologie du suicide rituel qui frappe justement les adolescents et les jeunes adultes du groupe depuis plusieurs décennies. Loin d’avoir le sens occidental d’un échec, il serait un moyen de résolution mythique du problème d’identité, une fin courageuse et glorieuse, voire métaphorique de la fin, rêvée, du Guerrier d’antan rejoignant les divinités
BENTUK REPRESENTASI MATEMATIS SISWA DITINJAU DARI SELF-EFFICACY PADA MATERI KEKONGRUENAN DAN KESEBANGUNAN DI KELAS IXA
Authors: Rohmah Afi Fatur , Mirza Ade , Fitriawan Dona
Published: April 2024

The poor performance of SMP Negeri 1 Binjai Hulu served as the inspiration for this study. students in solving math problems with an average score of 50.6 and still below the KKM which indicates that when solving math problems it is not optimal. The purpose of this study is to describe the form of mathematical representation of students at SMP Negeri 1 Binjai Hulu class IXA in solving problems of congruence and perpendicularity material in terms of Self-efficacy. The method used in this study is a qualitative method. The subjects in this study were 28 students of class IXA SMP Negeri 1 Binjai Hulu and 6 students to be interviewed. Data reduction, data presentation, and drawing conclusions are data analysis techniques that are used. The analysis of the data revealed that each student's responses to problems involving mathematical representation took different forms and included clues about issues with visual, verbal, and symbolic representation. Students with high self-efficacy are more optimal in answering questions, students with moderate self-efficacy have not maximized in using representation indicators so that there are some mistakes in solving problems, students with low self-efficacy as a whole have not achieved representation indicators well.
PENGEMBANGAN LKPD BERMUATAN KEARIFAN LOKAL UNTUK MENGUATKAN NILAI- NILAI KARAKTER PESERTA DIDIK PADA PEMBELAJARAN TEMATIK
Authors: Hauriah Hauriah
Published: April 2024

Penelitian ini bertujuan untuk 1) mengembangkan LKPD bermuatan kearifan lokal untuk menguatkan nilai-nilai karakter peserta didik dalam pembelajaran tematik, 2) mendeskripsikan kevalidan LKPD bermuatan kearifan lokal untuk menguatkan nilai-nilai karakter pada peserta didik dalam pembelajaran tematik, 3) menganalisis kepraktisan LKPD bermuatan kearifan lokal untuk menguatkan nilai-nilai karakter pada peserta didik dalam pembelajaran tematik. Penelitian ini menggunakan metode penelitian dan pengembangan Research and Development (R & D). Adapun teknik pengumpulan data yang digunakan dalam penelitian ini adalah komunikasi tidak langsung melalui lembar validasi dan angket. Kesimpulan dalam penelitian ini adalah Lembar Kerja Peserta Didik Bermuatan Kearifan Lokal yang telah di kembangkan oleh peneliti sangat layak di gunakan dan di aplikasikan dalam pembelajaran. Didalam proses pengembangan Lembar Kerja Peserta Didik menggunakan prosedur model pengembangan ADDIE. Dari proses pengembangan LKPD dapat dilihat peserta didik sangat antusias   dalam proses pembelajaran. Berdasarkan aspek penyajian, LKPD yang dikembangkan telah sesuai dengan kurikulum 2013, mudah dipahami, meningkatkan minat dan motivasi peserta didik dan sesuai dengan kemajuan zaman. Kepraktisan Lembar Kerja Peserta Didik (LKPD) Bermuatan Kearifan Lokal tema 9 Kayanya Negeriku diperoleh hasil persentase 74,8% dengan kriteria menarik. Keperaktisan LKPD dapat di lihat dari angket respon guru dan angket respon Peserta didik
2473-0653
Authors:   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, R Zhang , J Zhou ,   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, R Ding ,   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, L Zhang ,   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, S Liu ,   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, Y Chen ,   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, Y Li ,   Department of Social Medicine and Health Service Management, Army Medical University (Third Military Medical University), China, D Li ,   Department of Laboratory Medicine, University-Town Hospital of Chongqing Medical University, China
Published: April 2024

Background: The coronavirus disease (COVID-19) pandemic has posed a huge threat to global public health. The spread, prevention, and control of emergent infectious diseases are associated with several social health determinants. Social interventions addressing the social health determinants are crucial for controlling the transmission of virus. Objective: We aimed to explore the effectiveness of social interventions implemented in Western China to obtain new insights for controlling emergent global infectious diseases. Methods: A web-based study was conducted in March 2020 in Western China. Data on government-implemented social interventions were collected using a structured questionnaire from the perspectives of community residents. Propensity score matching (PSM) analysis was performed to explore the effectiveness of social interventions. Results: A total of 1,450 community residents were included in the current study, and 88 COVID-19 patients were included after PSM. Among 1,450 community residents, >80% reported that community responses to COVID-19 reached them through radio, slogans, and gatekeepers in the community, and almost all of them provided a positive response to social interventions. Residents who positively responded to these interventions were more likely to adopt behaviors that prevent the spread of COVID-19 than COVID-19 patients (P<0.05). Conclusion: Our data suggest that the timely provision of social interventions has been effective in Western China, and these findings could be used to establish international multi-sector collaborative efforts to successfully control COVID-19. We conclude that social interventions provided in the communities are crucial for the control of COVID-19.
A Review on Bite Marks in Forensic Dentistry
Authors:   Department of Oral Medicine & Radiology, A.J Institute of Dental Sciences, Rajiv Gandhi University India, C Shebah , A Sheethal ,   Department of Oral Medicine & Radiology, A.J Institute of Dental Sciences, Rajiv Gandhi University India, BR Harshita ,   Department of Oral Medicine & Radiology, A.J Institute of Dental Sciences, Rajiv Gandhi University India, P Preethi ,   Department of Oral Medicine & Radiology, A.J Institute of Dental Sciences, Rajiv Gandhi University India, RK Prasanna ,   Department of Oral Medicine & Radiology, A.J Institute of Dental Sciences, Rajiv Gandhi University India
Published: April 2024

Forensic odontology plays an essential part in recognizing the bodies of victims in mass casualties, crime scenes and terrorist attacks. Bite marks are a significant substitute in crime investigation, when routine means of identification cannot be performed owing to distortion of facial structures and fingerprints. Forensic odontologists are associated with the analysis of bite marks and presentation of the evidence in the court. Bite mark identification is based on the exclusivity and singularity of individual dentition. This article reviews the importance of bite marks analysis, methods of identification and recovery of bite mark evidence and its role in forensic investigation.
Use of a Posterior Bite Block Modified with TPA and Palatal Crib for Treating Open Bite in Growing Individual: A Case Report
Authors:   Assistant Professor, Pushpagiri College of Dental Sciences, India, JJ Daniel , A Nizar ,   Post graduate student, AJ Institute of Dental Sciences, India, KN Shetty ,   Professor & HOD, Department of Orthodontics, AJIDS, India, A Kumar ,   Reader, Department of Orthodontics, AJIDS, India
Published: April 2024

Background: The aim of this paper is to illustrate the use of a Posterior bite block modified with TPA and Palatal crib to obtain the vertical control of maxillary molars, restrict tongue pressure as well as Intruding posterior molars thereby auto rotating mandible. Case Report: Use of posterior bite block modified with TPA and Palatal crib for correcting Anterior Open bite in growing individual is illustrated. Patient was successfully treated, and the open bite was fully corrected thanks to molar intrusion, following counter clockwise rotation of the mandible and tongue correction. Finishing of alignment was performed in phase II of the treatment with conventional appliances. Conclusion: Posterior bite block modified with TPA and Palatal crib proved to be effective in controlling the vertical position of maxillary molars promoting the counter-clockwise rotation of the mandible and stimulating a different tongue posture.
Prescription Opioid Pain Medication Use among Patients Attending a US Dental College Clinic: Prevalence and Implications
Authors:   Department of General Dentistry, Dental College of Georgia, Augusta University, Augusta, Georgia, GA 30912-1128, USA., M Chana , R Harris ,   Department of General Dentistry, Dental College of Georgia, Augusta University, Augusta, Georgia, GA 30912-1128, USA., KL Lewis ,   Smile Blue Ridge, 47 Dunbarton Farm Rd, Blue Ridge, GA 30513, USA., W Abebe ,   Department of Oral Biology and Diagnostic Sciences, Dental College of Georgia, Augusta University, Augusta, Georgia, GA 30912-1128, USA.
Published: April 2024

Purpose: Due to the increased opioids abuse in US during the past several decades, efforts have been made to counter this trend through regulation of use of prescription opioid pain medications. This study assesses the use of these medications by adult dental patients attending a US dental college clinic during February 2017 to October 2021. Methods: A self-administered anonymous questionnaire was used to gather data from patients on demographics and patterns of utilization of medications. Results: Among the patients included in the study, the majority were 51 to 70 years of ages, females, Caucasians, and with minimum high school education. Nine prescription opioid medications were used, and of these, hydrocodone and oxycodone were more common. Most patients used single medications, of which the majority were utilized for a few days up to 4 weeks. Nearly all medications were prescribed by 10 different health profession specialists, and the majority comprised emergency medicine physicians, primary health care practitioners and dentists. Most patients used their medications as intended, without sharing with others, and also expressed their satisfactions with the medications they used. Conclusions: The study suggests that the recently reported opioid epidemic in US is less related to use of prescription medication, but to other external factors, including the non-medical use of potent synthetic compounds, such as fentanyl, as widely reported in the literature. Such a recognition, while warranting further studies on the topic, provides additional justifications for enhanced focus on this aspect of opioid abuse.
The Visibility and Affecting Factors of Bifid Mandibular Condyles on Panoramic Radiography
Authors:   Associate Professor, Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ondokuz Mayis University, Turkey, Zengin Ayse Zeynep , Karabiyik Ahmet Eren ,   Research Assistant, Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ondokuz Mayis University, Turkey, Cam Kübra ,   Research Assistant, Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ondokuz Mayis University, Turkey, Dogruer Hande S ,   Research Assistant, Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ondokuz Mayis University, Turkey, Rizeli Lale ,   Research Assistant, Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ondokuz Mayis University, Turkey, Sumer Ayse Pinar ,   Professor, Research Assistant, Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ondokuz Mayis University, Turkey
Published: April 2024

Aim: The aim of this study was to determine the visibility of Bifid Mandibular Condyle (BMC) and affecting factors on panoramic radiography compared with Cone Beam Computed Tomography (CBCT). Material and Methods: Radiologically depression or notch on superior condylar surface or duplication of condylar head with continuous cortex on CBCT images was considered as BMC. Characteristics of BMC such as location, type, groove type, depth, and horizontal angle on CBCT images were noted. Panoramic radiographs of 63 BMC and 65 normal mandibular condyles confirmed on tomographic images were evaluated by three groups of observers with different experiences.According to the results, the common correct and incorrect estimations were compared. Results: There was no statistically significant difference between the results of the observers. Despite there was no statistically significant difference between the characteristics of BMC according to whether the estimations were correct or incorrect. (p>0,050), it was determined that the horizontal angle of the BMC that observers stated correctly was 20.5% less than the cases with bifid condyles that they stated incorrectly. Conclusion: In conclusion, experience of clinicians had no effect on the visibility of BMC. Panoramic radiographs frequently misread bifidity and bifidity was only confirmed by the CBCT. However, it can be estimated that when the angle between the condylar head and the horizontal plane become closer, BMC is more likely to be detected on panoramic radiographs. Further studies are required to determine which factors have effect on visibility of BMC on panoramic images.
Topic: All-on-Four Concept Literature Review
Authors:   Faculty of Dental Medicine, University of Medicine, Tirana, Albania, Isufi Ramazan , Xhajanka Edit ,   Faculty of Dental Medicine, University of Medicine, Tirana, Albania, Thodhorjani Anis ,   Faculty of Dental Medicine, University of Medicine, Tirana, Albania, Hysenaj Neada ,   Faculty of Dental Medicine, University of Medicine, Tirana, Albania, Lela Fatmir ,   Faculty of Dental Medicine, University of Medicine, Tirana, Albania, Bara Silvana ,   Faculty of Dental Medicine, University of Medicine, Tirana, Albania, Isufi Renato ,   Faculty of Dental Medicine, University of Medicine, Tirana, Albania
Published: April 2024

In patients with total edentulism, dental implant treatment is a treatment model which has been accepted scientifically, and with long-term outcomes [1,2]. Dental implants with immediate function by making implant-supported fixed full-arch restorations are becoming the gold standard in dental implantology [3-5]. Normally in literature successful prostheses are made using [6-8] implants in the maxilla and 6 implants in the mandible and applying posterior cantilever extension where it is necessary, in these treatments, hygiene controls can be easily performed especially in full arch screw-retained fixed prostheses [7-9]. In some cases maxillary sinuses for maxilla restricts the implant placement in the posterior region. The posterior implant treatment is also difficult in patients with resorbed mandible with a mandibular nerve located at the top of the alveolar crest. The all-on-four implant concept has been developed to prevent these disadvantages presented by Malo for the first time in 2003 and the all-on-four concept that began to be used in atrophic full arch mandibular and in the maxilla in 2005. In this technique implants are positioned in the pre-maxillary region in the maxilla and in the inter-foraminal region in the mandible.Anterior implants are placed to the lateral incisor sites or canine/first premolar region, posterior implants are placed to the second premolar or first molar region [12-16].
Efficacy and Safety of Dupilumab in Prurigo Nodularis: A Real-World Study
Authors:   Department Head, School of Computer Science and Engineering, Nanyang Technological University, Nanyang Avenue, Singapore, Li Xiaoli
Published: April 2024

Prurigo Nodularis (PN) is a chronic inflammatory skin disease characterized by severe itching accompanied by multiple nodules throughout the body. There is currently no effective drug-targeted treatment for PN. Dupilumab is a fully human monoclonal antibody which can suppress the Th2 inflammatory reaction. We aimed to assess the efficacy and safety of dupilumab in PN. There were 29 PN patients who received dupilumab treatment for four months. Serum total Immunoglobulin E (Ig E), eosinophil counts, Dermatology Life Quality Index (DLQI), and Numeric Rating Scale (NRS) were assessed on patients before and after treatment. And we count the vaccination of novel coronavirus pneumonia (COVID-19) in patients and the impact on skin diseases and treatment measures after vaccination. Plotting was performed using GraphPad Prism8, and statistical analysis was performed using PASW Statistics18. The eosinophil counts in patients higher decreased to normal, and the Ig E levels gradually decreased and tended to normal levels after receiving dupilumab injection. The average DLQI score at baseline was 23.93±0.66, and decreased to 11.66±0.55 (P<0.01) and 1.83±0.22 (P<0.01) at 1-month and 6-month follow-up of treatment, respectively. The average NRS score at baseline was 9.79±0.08, and decreased to 3.52±0.23 (P<0.01) and 0.31±0.15 (P<0.01) at the 1-month and 6-month follow-up of treatment, respectively. Our study shows that dupilumab has achieved good efficacy in PN with few adverse reactions and high safety. We can recommend that patients follow the advice of specialists to be vaccinated and under the condition of stable disease, separated from dupilumab treatment for one week.
Clinical Effect of Unani Medicine in a Case of Warts with Medical Images Before and After Treatment
Authors:   Colocation Research Center, RRIUM, JJ Hospital, India, Bano Humaira , Qureshi Masroor Ali ,   Colocation Research Center, RRIUM, JJ Hospital, India
Published: April 2024

The Unani (Greek) system of medicine is one of the oldest forms of medicine used in various parts of the world. Despite its long journey, this medicine continues to thrive due to its vital role in the field of medical sciences. It encompasses comprehensive knowledge of the underlying causes and definitive treatments. In Unani Research OPDs, patients with chronic illnesses, especially those who have exhausted various integrative treatments, come seeking a cure. One such patient was a 33-year-old female who sought treatment for grainy growths on her fingers. She has prescribed a powder containing Mazu (Quercus infectoria Oliv), Murdar Sang (Litharge), Sandal (Santalum album), and kafoor (Camphor). After using this powder for 15 days, the patient experienced approximately 87.735% improvement. These results suggest that it could be a potential drug of choice for treating warts, deserving a large-scale clinical trial and the use of specialized scales to achieve even better and more significant results.
Proliferative Verrucous Leukoplakia: An Update
Authors:   Division of General Dentistry, Health Campus, Paul Sabatie, J Gante , A Dubuc ,   Division of General Dentistry, Health Campus, Paul Sabatie, S Laurencin-Dalicieux ,   Division of General Dentistry, Health Campus, Paul Sabatie, S Cousty ,   Division of General Dentistry, Health Campus, Paul Sabatie
Published: April 2024

Objectives: Proliferative verrucous leukoplakia was first described by Hansen et al. in 1985. It is a rare form of oral leukoplakia with a high risk of malignant transformation. A review of the scientific literature indicates that there is no consensus on the management and follow-up of proliferative verrucous leukoplakia. This article aims to provide an update on the epidemiological, clinical, histological and immunohistochemical, diagnostic, treatment and follow-up data on the disease. Materials and Methods: We performed a narrative review by searching the Pubmed and Google Scholar databases using keywords. Results: 93 out of 446 selected articles were selected for analysis. The majority of affected patients are women. The lesions are multifocal and usually occur on the gingiva and alveolar mucosa. The aetiology is idiopathic. The diagnosis is retrospective and based on the history of the disease. Apart from mapping the lesions using repeated biopsies to detect a malignant area progression, there is no recommended treatment to cure the disease. Conclusion: The current understanding of this entity is based on the analysis of retrospective studies with weak scientific evidence. Expert recommendations regarding follow-up and management would facilitate better control of recurrence and malignant transformation rates.
Dorsal Pterygum and Nail Lichen Planus
Authors:   Clinic of Dermatology and Venerology “Derma Expert”, Russian Federation, Russia, RV Saranyuk
Published: April 2024

A 62-year-old patient complained of changes in the nail plates of the fingers. According to the patient, the changes began 20 years ago with a gradual deterioration in his condition. The patient's skin and mucousa are not involved. During clinical examination, there is a change in the integrity of the nail plate, growth of the skin of the proximal nail fold towards the nail bed (dorsal pterygum) with splitting of the nail. On the nail plate of the second finger of the right hand. Dermoscopic examination reveals triangular growth of the skin of the proximal ridge, nail separation on the free edge and multiple longitudinal grooves
Interfacial Water Flipping and Electrostatic Fields at the Electrode:Electrolyte Interface from operando Nonlinear Optical Spectroscopy
Authors: Speelman Raiden , Geiger Franz
Published: April 2024

While water's oxygen is the electron source in the industrially important oxygen evolution reaction, the strong absorber problem clouds our view of how the Stern layer water molecules orient themselves in response to applied potentials. Here, we report nonlinear optical measurements on nickel electrodes held at pH 13 indicating a disorder-to-order transition in the Stern layer water molecules prior to the onset of Faradaic current. A full water monolater (1.1 x 10^15 cm-2) aligns with oxygen atoms pointing towards the electrode at +0.8 V and the associated work is 80 kJ mol-1. Our experiments identify water flipping energetics as a target for understanding overpotentials, advance molecular electrochemistry, provide benchmarks for electrical double layer models, and serve as a diagnostic tool for understanding electrocatalysis.
A General Method for Synthesizing van der Waals and Non-van der Waals Moiré Superlattices from Molecular Crystals
Authors: Bhakat Arin , Dey Ujjala , Chattopadhyay Arun
Published: April 2024

Quantum materials have received a lot of interest in recent years because of their unusual and remarkable properties. Angular stacking of two-dimensional (2D) nanoscale crystalline sheets into interacting superstructures, such as moiré superlattices, can result in unique physical and chemical properties solely through interlayer interactions. Moiré superlattices are generally formed from 2D van der Waals (vdW) materials such as graphene, hexagonal boron nitride (hBN), and transition metal dichalcogenides (TMDCs). These superlattices are fabricated using mechanical positioning of the constituent lattices; however, their scalable fabrication is challenging. Further, current interests in the field demands the development of a generalized approach for high-quality and scalable moiré superlattice fabrications. Chemistry-based methods in the liquid media may be helpful in this regard. Here, we report the development of a generalized method for synthesising moiré superlattices from covalent molecular crystals, ionic crystals, and metal complex crystals, which consist of finely grounding bulk crystals and sonicating the grounded crystals in an ultrasonic bath at moderate temperature in the presence of a solvent system to obtain a dispersion of the superlattices. This discovery opens up new options for designing and fabricating moiré superlattices from various materials and for studying the chemistry of nanoscale 2D moiré materials.
The role of direct oral anticoagulants in cancer-associated thrombosis. Review of clinical guidelines and real practice
Authors: Tereshin Oleg S.
Published: April 2024

Oncology is one of the undisputable leaders of the present day medicine in terms of innovations and research. Globalization and a high number of randomized clinical trials generate an ever increasing amount of new data, clinical guidelines on cancer treatment, complications prevention and supportive care. Modern oncology practice demands vast and firm knowledge on venous thromboembolism treatment and prevention. The article is a survey of the present day clinical guidelines and real world data in the field of cancer-associated thrombosis.
Venous thrombosis during systemic antitumor therapy: risks, prognosis, treatment. A review
Authors: Fedyanin Mikhail , Rumyantsev Alexey A. , Tryakin Alexey A.
Published: April 2024

Venous thromboembolic events (VTE and ТЕ) in cancer are a complex and multicomponent process involving various non-modifiable and modifiable factors that increase or reduce the risk of abnormal thrombus formation. The paradigm of prevention and treatment of VTE in cancer patients has significantly changed with the introduction of new oral anticoagulants; however, the choice of a particular agent remains challenging for practitioners. This review aims to address the VTE development mechanisms in cancer patients, compare different scales in predicting VTE occurrence, and compare the effectiveness and tolerability of anticoagulant therapy in various clinical situations.
Laparoscopic pelvic exenteration for malignant tumors of the female reproductive system: a case series
Authors: Lyadov Vladimir K. , Nevrov Andrey S. , Garipov Marat R. , Moskalenko Alexey N. , Simbiryov Timofey V. , Galkin Vsevolod N.
Published: April 2024

Background. Surgical treatment of locally advanced and recurrent malignant neoplasms of the female reproductive system is a difficult task requiring extensive multivisceral resections and exenteration. Minimally invasive access allows for less traumatic intervention and improved visualization, potentially leading to improved oncologic outcomes and fewer complications.
Aim. To evaluate intraoperative and early postoperative results of laparoscopic pelvic exenterations.
Materials and methods. 12 laparoscopic pelvic exenteration were performed between December 2022 and September 2023. Strict selection of patients for laparoscopic access was not performed. Local recurrence was noted in 8 patients, in 3 cases there was continued growth after chemoradiotherapy. 8 patients had a history of pelvic irradiation. 9 women had received drug therapy in the past.
Results. Total exenteration was performed in 5 patients, anterior exenteration in 5 patients, and posterior exenteration in 2 patients. The average duration of the operation was 420.8±99.2 (300–625) minutes, the average volume of blood loss was 166.7±98.5 (100–400) ml. Significant postoperative complications (Clavien–Dindo grade III) were registered in two cases: pelvic abscess that required relaparoscopy and sanation, as well as intra-abdominal abscess – drained under ultrasound control. In one case on the 18th day after the surgical intervention a fatal outcome (Clavien–Dindo grade V) due to pulmonary embolism was registered. The median postoperative bed-day was 14.5 (8–32) days.
Conclusion. Laparoscopic access for pelvic exenteration improves intraoperative and early postoperative results. It is necessary to further improve the techniques of this intervention and to define clear indications for its performance, which will allow to achieve better treatment results.
Toxicity and safety of the combination of lenvatinib with pembrolizumab in patients with advanced renal cell cancer: The Russian phase IV observational study
Authors: Volkova Maria I. , Kalpinskiy Alexey S. , Goncharova Olesya A. , Menshikov Konstantin V. , Karabina Elena V. , Dergunov Aleksand S. , Polshina Natalya I. , Alexandrova Elena N. , Lebedinets Andrey A. , Panov Alexey К. , Sultanbaev Alexander V. , Usynin Evgeny A. , Volkonskiy Mikhail V. , Mikhalyuk Viktorya V. , Zykov Ruslan A. , Anzhiganova Yulia V. , Gusniev Magomed A. , Igumnova Elena N. , Kuzmicheva Svetlana V. , Pokataev Ilya A. , Olshanskaya Anna S. , Pervakova Natalia I. , Parsadanova Elvira L. , Sannikova Tatyana A. , Bystrov Alexandr  A. , Dubovichenko Daria M. , Miliausha Mukhitova R. , Chubenko Viacheslav A. , Shkret Konstantin A. , Gorshenina Mariya N. , Davlatova Mavzhuda К. , Kosareva Alina E. , Lutoshkina Olga A. , Maslova Oxana A. , Makhnutina Maria V. , Mishina Anna V. , Murzalina Makhabbat Zh. , Podyacheva Oksana A. , Kalinin Sergey A. , Mailyan Ovsep A. , Safarova Alfiya R. , Semenova Ksenia O. , Strokova Mariya A. , Urashkina Ekaterina Yu. , Shmygina Olesya S.
Published: April 2024

Aim To evaluate the safety and toxicity of lenvatinib with pembrolizumab in unselected patients with advanced renal cell carcinoma (RCC).
Materials and methods. The Russian phase IV observational study included 151 patients with advanced RCC who received lenvatinib with pembrolizumab in a standard dose regimen in 36 clinical centers of the Russian Federation. Most patients were diagnosed with clear cell RCC (n=145, 96.0%), with synchronous (n=77,51.0%) metastasesof more than one location (n=111,73.5%), removed primary tumor (n=98, 64.9%) and were classified into intermediate and poor IMDC prognostic groups (n=111, 73.5%). Median follow-up was 9.6 (1—68) months.
Results. Any adverse events (AEs) were noted in 109 (72.2%), grade ≥3 AEs-in 26 (17.2%), serious AEs-in 9 (6.0%) of 151 patients. There were no deaths caused by AEs. AEs were an indication for lenvatinib dose reduction in 32 (21.2%), a dose interruptions in lenvatinib treatment in 21 (13.9%), and lenvatinib discontinuation in 2 (1.3%) cases. A dose interruptions in pembrolizumab therapy due to AEs was necessary in 15 (9.9%) cases. Both combination drugs were discontinued due to toxicity in 10 (6.6%) cases. AEs were assessed as immune-mediated in 24 (15.9%) patients (grade 3-4 - n=7, 4.6%) and required the prescription of high doses of glucocorticosteroids in 2 (1.3%) patients.
Conclusions. A Russian observational study confirmed the acceptable safety profile of lenvatinib plus pembrolizumab therapy in patients with advanced RCC.
Aging and Media Studies: Modern Society Transformation and Disciplinary Turning for
The Future
Authors: 胡 泳 , 王 梦瑶
Published: April 2024

人口老龄化是目前中国社会面对的结构性变化之一。“老龄化与媒介”研究作为跨学科研究领域,需要对新的社会现象作出理论与方法上的回应。本研究通过检视中国在老龄化进程与老年学建设上的位置,提出老龄化问题的社会意涵应该得到更多学术关注,未来研究应该更多采取文化批判视角,对数字媒体、智能技术、平台治理等与老年人的关系加以审视。
Mediatization of Governance?—Rethinking the Local Approach of Mediatization Studies
in China
Authors: 戴 宇辰 , 葛 家明
Published: April 2024

由于媒介与治理的互动在中国语境中愈益显著,学者们往往引用“媒介化”作为理论资源对之进行解释,并以此形成了“媒介化治理”的本土研究领域。当前国内媒介化治理研究存在着“前台与后台”“事件与过程”“行动与结构”三组范畴断联的问题,造成该理论经验解释上的难点。本研究通过援引政治社会学中的“结构过程”范式,尝试对本土媒介化治理研究的中层分析框架进行针对性建构,并结合J省A
县融媒体中心建设的经验案例进行检验。最终,本研究尝试归纳出本土媒介化治理研究的“结构过程”取径,并希望能够对更广泛的本土媒介化研究提供一定的路径补充。
Scattering mechanisms in MOS/SOI devices with ultrathin semiconductor layers
Authors: Walczak Jakub , Majkusiak Bogdan
Published: April 2024

Main scattering mechanisms affecting electron transport in MOS/SOI devices are considered within the quantum-mechanical approach. Electron mobility components (i.e., phonon, Coulomb and interface roughness limited mobilities) are calculated for ultrathin symmetrical DG SOI transistor, employing the relaxation time approximation, and the effective electron mobility is obtained showing possible mobility increase relative to the conventional MOSFET in the range of the active semiconductor layer thickness of about 3 nm.
Silicon microelectronics: where we have come from and where we are heading
Authors: Łukasiak Lidia , Jakubowski Andrzej , Pióro Zbigniew
Published: April 2024

The paper briefly presents the history of microelectronics and the limitations of its further progress, as well as possible solutions. The discussion includes the consequences of the reduction of gate-stack capacitance and difficulties associated with supply-voltage scaling, minimization of parasitic resistance, increased channel doping and small size. Novel device architectures (e.g. SON, double-gate transistor) and the advantages of silicon-germanium are considered, too.
Preface
Authors: Jakubowski Andrzej , Łukasiak Lidia
Published: April 2024

Preface
Methods for evaluation packet delay distribution of flows using Expedited Forwarding PHB
Authors: Kaczmarek Sylwester , Narloch Marcin
Published: April 2024

The paper regards problem of providing statistical performance guarantees for real-time flows using Expedited Forwarding Per Hop Behavior (EF PHB) in IP Differentiated Services networks. Statistical approach to EF flows performance guarantees, based on calculation of probability that end-to-end packet delay is larger than certain value, allows larger network utilization than previously proposed deterministic approach. In the paper different methods of packet delay distribution evaluation are presented and compared. Considered cases comprise evaluation of delay distribution models for the core network and evaluation of end-to-end packet delay in the network consisted of edge node and chain of core nodes. Results obtained with aid of analytical models are compared with simulation results.
Sharing tactical data in a network-enabled coalition
Authors: Busch James , Russo Rita
Published: April 2024

The NATO Command, Control and Consultation Agency (NC3A) is a participant in a coalition project called the Shared Tactical Pictures (STP). The aim of STP is to develop methods and techniques to enable the sharing of a wide variety of information - e.g., ground surveillance sensors, airborne sensor platforms, recognized pictures, and much more - across a widely distributed network. As NATO changes its war-fighting paradigm from a well-known and stable alliance configuration to more flexible, coalition-based operations, solving the problem of information-sharing has never been more important. This paper discusses the technical and operational developments being explored in STP.
Modelling and simulation of combat operations in SimCombCalculator application
Authors: Nowicki Tadeusz
Published: April 2024

The basis of the article is mathematical discrete problem connected with local military battle. The problem consists of two dependent problems. One of them shows how to find our troops allocation to enemy`s troops. The battle damage assessment function for the problem is proposed. The second problem is connected with finding global strategy of attack. Local battle is described by modified Lanchester model. Two level logistic model is built for describing materials and munitions resupply management processes. This idea was used in computer simulator SimCombCalculator. The paper shows how to use this simulator for finding attack strategy from the platoon to brigade level.
Semi-automatic test system for characterization of ASIC/MPWS
Authors: Zając Jerzy , Wójcik Janusz
Published: April 2024

A measurement system for integrated circuit testing has been developed. It consists of a semi-automatic probe station and a set of measurement equipment controlled by commercially available measurement software. The probe station is controlled by dedicated software. Both the measurement and station-control software communicate using the DDE protocol. The measurement system is flexible. It is particularly suitable for semi-automatic testing of multi-project wafers. Output data generated by the system is used for the characterization of the CMOS technologies.
Properties of Al contacts to Si surface exposed in the course of plasma etching of previously grown nanocrystalline c-BN film
Authors: Firek Piotr , Werbowy Aleksander , Szmidt Jan , Olszyna Andrzej R.
Published: April 2024

Properties of Al electric contacts to Si(p) surface exposed to fluorine-based plasma etching of nanocrystalline cubic boron nitride (c-BN) film grown previously were studied and compared to the properties of Al contacts fabricated on pristine or dry etched surface of Si(p) wafers. In addition, a part of the investigated samples was annealed in nitrogen atmosphere at the temperature of 673 K. Analysis of contract properties is based on current-voltage (I-V) measurements of the produced Al-Si structures. The presented investigations were performed in order to evaluate the efficiency of the applied plasma etching method of nanocrystalline c-BN from the viewpoint of its influence on the properties of metal contacts formed subsequently and thus on the performance of electronic devices involving the use of boron nitride.