bluuebunny/crossref_metadata_2025 huggingface dataset:
Анализ демонстрации аутентичных художественных фильмов как средства повышения мотивации студентов к изучению иностранного языка
Authors: Левченко В.В. , Баймухаметова К.И , Киреева И.А
Published: September 2023

Актуальность исследования в статье заключается в необходимости наблюдения процесса использования иностранного языка в лингвистическом и культурологическом аспектах в ходе демонстрации аутентичных художественных фильмов, что интенсифицирует практику обучения иностранному языку в высшей школе. Целью исследования является анализ демонстрации аутентичных художественных фильмов как средства повышения мотивации студентов к изучению иностранного языка. В результате была установлена ключевая методика обучения иностранному языку, основанная на демонстрации и обсуждении аутентичных художественных фильмов, которая способствует эффективному формированию всех видов речевой деятельности в совокупности и повышает мотивацию студентов к изучению английского языка
Педагогическое сопровождение детей с нарушением эмоционально-волевой сферы
Authors: Маслова Т.А , Царева Е.Н.
Published: September 2023

В статье указаны факторы, влияющие на эмоционально-волевые нарушения. Перечисляются причины нарушения эмоционального неблагополучия детей. Предлагаются методы педагогического сопровождения детей с нарушением эмоционально-волевой сферы
Тенденции развития иноязычного образования в высшей школе в контексте цифровизации
Authors: Шапкарина Е.И.
Published: September 2023

В статье рассматриваются тенденции развития иноязычного образования в высшей школе в условиях цифровизации. Дается характеристика современных цифровых образовательных ресурсов. Делается вывод о преимуществах цифрового иноязычного пространства в учебном процессе.
Особенности речевых функций у студентов с разными типами профиля латеральной организации мозга
Authors: Букатова Д.В
Published: September 2023

Статья посвящена результатам исследования особенностей речевой деятельности у студентов с разными типами профиля латеральной организации (ПЛО). Выявлено, что ПЛО вносит специфику в речевые функции. Полученные результаты могут быть актуальны в педагогике при организации более качественного учебного процесса
Küçük hücreli akciğer kanserinde daha fazla kombine kemoterapi ile atezolizumab kullanımı sağkalımı uzatır mı?
Authors: DEMİR Bilgin , AKGÜL Ömer Faruk , AYTAÇ Ali , AÇLAN Ayhan , BALÇIK Onur Yazdan , UZUN Mehmet , OKTAY Esin
Published: September 2023

Amaç: Küçük hücreli akciğer kanserinde (KHAK) yaklaşık 50 yıldır standart birinci basamak tedavi platin bazlı kemoterapi ile kombine etoposid rejimidir. Atezolizumabın yaygın evre KHAK birinci basamak tedavisinde kemoterapi ile kombine kullanımı yakın zamandan sağkalımı iyileştirdiği randomize bir çalışmada gösterilmiştir. Immunoterapi tedavisi uygulanmayan KHAK’li hastalara standart 6 kür platin bazlı kemoterapi uygulanarak en etkili sağkalım sonuçlarına ulaşılırken, atezolizumabın randomize çalışmasında standart 4 kür kemoterapi uygulanmıştır. Bu retrospektif çalışma, yaygın evre KHAK birinci basamak tedavisinde 6 kür kemoterapi ile kombine atezolizumabın gerçek yaşam verilerini sunmayı amaçlamaktadır.

Gereçler ve Yöntemler: Çalışmaya kliniğimizdeki yaygın evre KHAK tanılı ve birinci basamak indüksiyon fazında karboplatin-etoposid artı atezolizumab ile kombine minimum 6 siklus tedavi alan hastalar dahil edildi. İndüksiyon fazı tamamlanan hastalara idame fazında atezolizumab 1200 mg 3 haftada bir uygulandı. İndüksiyon fazında 6 siklus atezolizumab ile kombine kemoterapiden az tedavi alan hastalar ile laboratuvar verileri eksik olan hastalar çalışma dışı bırakıldı. Hastaların özellikleri, uygulanan tedaviler ve tedaviye yanıt oranları ile sağ kalım verileri incelendi. Sağkalımı verilerini belirlemek için Kaplan-Meier testi kullanıldı ve metastaz bölgelerinin etkileri log-rank testi kullanılarak analiz edildi.

Bulgular: Kriterleri karşılayan 24 hasta dahil edildi. Ortanca yaş 64 idi ve üçte ikisinde komorbid hastalık vardı. Medyan kemoterapi döngüsü sayısı 6 (6-12) ve atezolizumab döngüsü 8 (6-54) idi. Medyan 9,4 aylık takipten sonra medyan progresyonsuz sağkalım (PFS) ve genel sağkalım (OS) sırasıyla 9.5 ay (%95 GA 0.0-25.8) ve 30,1 aydı (%95 GA 3.26-57.004). Genel yanıt oranı %87.5 idi. Metastatik bölge sayısı (p = 0.77) ile OS arasında anlamlı bir fark bulunamadı. Hastaların yarısından fazlasında derece 3 yan etki gözlendi. En sık yan etkiler hematolojikdi ve toksisiteler yönetilebilirdi.

Sonuç: Bu gerçek yaşam verileri, yaygın evre KHAK birinci basamak tedavisinde indüksiyon fazında en az altı siklus kemoterapi ile kombine atezolizumab etkiliğini ve güvenliliğini doğrulamaktadır.
Patient with CADASIL – a diagnostic challenge
Authors: Węgrzynek Julia , Tomaszewska Agnieszka , Wawrzkiewicz-Witkowska Angelika
Published: September 2023

WSTĘP: Mózgowa autosomalnie dominująca arteriopatia z podkorowymi zawałami i leukoencefalopatią (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy – CADASIL) jest uwarunkowaną genetycznie i dziedziczoną w sposób autosomalnie dominujący chorobą małych naczyń. Jej wystąpienie wiąże się z mutacją w genie NOTCH3. Pierwsze objawy kliniczne pojawiają się w 3. lub 4. dekadzie życia, a poprzedzone są zmianami leukodegeneracyjnymi, które najlepiej uwidacznia rezonans magnetyczny (RM). Częstość występowania choroby określa się na 2–5 osób na 100 000. Obraz kliniczny pacjentów z CADASIL jest heterogenny. Najczęstsze objawy to nawracające udary, przemijające ataki niedokrwienne, przyczyniające się do deficytów poznawczych, oraz migreny z aurą. Pomimo coraz powszechniejszej znajomości CADASIL choroba ta wciąż stanowi wyzwanie diagnostyczne. OPIS PRZYPADKU: 60-letni mężczyzna został skierowany do poradni genetycznej z podejrzeniem CADASIL. Pierwsze symptomy choroby pojawiły się u niego prawdopodobnie w wieku 40 lat (1998 r.) w postaci zmian radiologicznych. Rezonans magnetyczny ujawnił wówczas okołokomorowe obszary hiperintensywnego sygnału w sekwencji T2-zależnej. W kolejnych latach na podstawie wykonywanych RM pacjenta diagnozowano w kierunku stwardnienia rozsianego oraz ostrego rozsianego zapalenia mózgu. W wieku 58 lat pacjent został przyjęty na oddział neurologii po napadzie padaczkowym. Rezonans magnetyczny wykazał okołokomorowe i nadnamiotowe zmiany istoty białej oraz lakuny poudarowe. Wysunięto podejrzenie, że przyczyną jest CADASIL. W poradni genetycznej diagnozę potwierdzono badaniami genetycznymi. Wykryto wariant patogenny NM_000435: c.268C > T (p.Arg90Cys). WNIOSKI: W diagnostyce różnicowej CADASIL należy brać pod uwagę choroby demielinizacyjne. Postawienie właściwej diagnozy ułatwia dokładny wywiad rodzinny oraz zestawienie go z wynikami badań obrazowych.
Bacillus valezensis: A New Plant Growth Promoting Rhizobacterium for Plant Growth Promotion and Inhibition of Rhizoctonia bataticola for the Management of Dry Root Rot of Chickpea
Authors: Sunkad Gururaj , Patil Meghana S. , Joshi Ranjana
Published: September 2023

Background: Chickpea production is threatened by dry root rot disease in recent years. The disease is caused by soil borne fungus Rhizoctonia bataticola (Taub) Butler with its pycnidial stage Macrophomina phaseolina (Tassi) Goid. Bacillus spp. is a rod shaped and gram negative rhizobacterium which is predominant in the soil. Hence, considering the economic importance of disease, the present investigation was carried out to repress the pathogen by using indigenous Bacillus spp. strains related to antagonistic potential and plant growth promoting traits Methods: Thirty indigenous bacterial PGPR strains were isolated from healthy rhizospheric soil samples of chickpea and their antagonistic potential was studied. Later, the potential ones were examined for plant growth promoting traits. The promising strains were identified at molecular level 16S rDNA. Results: All thirty PGPR strains of rhizospharic Bacillus were potentiality antagonistic against R. bataticola and nine strains showed more than 50 per cent inhibition of the pathogen. Out of nine strains, four strains recorded more growth promoting traits and they were identified at molecular level as Bacillus cereus, Bacillus velezensis, Bacillus subtilis and Bacillus subtilis sub sp. Subtilis. Bacillus valezensis is a new report on rhizosphaeric PGPR against R. bataticola in chickpea.
Apresentação
Authors: Magnaghi Alberto , Campello Cabral Renata , Monteiro de Andrade Carlos Roberto
Published: September 2023

Esse texto é a apresentação feita pelo urbanista italiano Alberto Magnaghi ao volume Del Destino della Città, uma antologia de textos de Choay traduzidos para o italiano e publicada em 2008.
A antologia organizada por Magnaghi inclui oito textos de Pour une Anthropologie de l’Espace (2006). A eles Magnaghi acrescentou apenas a introdução de Choay às Mémoires do Barão Haussmann, publicada em 2000. As seções são em número de três e pensadas a partir da ótica de um “arquiteto-urbanista militante”, o que o leva a articular as reflexões que permeiam os textos de Choay com os desafios contemporâneos dos profissionais do campo do planejamento urbano, em diálogo direto com princípios caros à Escola Territorialista Italiana.
Alberto Magnaghi é Professor Ordinário Emérito de Planejamento Territorial no Departamento de Arquitetura da Universidade de Florença (DIDA), onde fundou e dirigiu o Laboratório de Projeto Ecológico dos Assentamentos (LaPEI) entre 1990 e 2016. Foi coordenador de um programa nacional de pesquisa e laboratórios experimentais sobre os temas do desenvolvimento local autossustentável e da representação identitária do território (1986-2010), tendo também coordenado diversos projetos e planos urbanísticos. Foi, ainda, presidente do Curso de Láurea Magistral em Planejamento e Projeto da Cidade e do Território junto ao Departamento de Ciências e Tecnologias Agrárias, Alimentares, Ambientais e Florestais (DAGRI). É presidente da Sociedade dos Territorialistas desde sua fundação, em 2011.
Nessa tradução, os termos estrangeiros usados por Magnaghi foram mantidos, de forma a aproximar o leitor brasileiro à experiência tida pelo leitor italiano. Muitos desses termos são em francês e indícios da aproximação de Magnaghi às interpretações feitas por Françoise Choay. Frases muito longas tornaram-se, por vezes, mais de uma sentença, em favor da clareza do texto. Os neologismos foram mantidos como tais, a partir de criação equivalente em português. Anota-se, por fim, que, na tradução das referências, foi feita normatização a partir da ABNT.
 
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Françoise Choay
Authors: Mugayar Kuhl Beatriz
Published: September 2023

Este texto aborda as proposições de Choay sobre a autenticidade, a partir de seu escrito publicado em 1995. Este artigo tem por intuito pontuar alguns temas, e não os esgotar, direcionando-os mais explicitamente para o campo disciplinar do restauro. Para tanto, primeiramente, são abordados aspectos de como a autenticidade foi entendida na Carta de Veneza e as dúvidas que gerou. Depois, são examinadas as noções de monumento e monumento histórico e suas relações com as visões culturais do tempo. A seguir, centra-se sobre aspectos das proposições de Choay sobre autenticidade, evidenciando a necessidade de análise rigorosa e crítica para enfrentar as questões. Evidencia-se a visão da autora de que a função memorial, a memória viva, deve também ser mobilizada para os monumentos históricos, para que não haja perda da competência de edificar, de estruturar a paisagem e de habitar no espaço e no tempo. Por fim, são apresentadas considerações de como essa discussão pode contribuir para a reflexão atual sobre a restauração.
Pluralismo político en el marco del postacuerdo y frente a la situación de defensores de derechos y líderes sociales en Colombia
Authors: Marín Beltrán Segundo Eurípides
Published: September 2023

El objetivo de este artículo estriba en analizar desde un punto de vista teórico y reflexivo, de qué forma se puede materializar la práctica del pluralismo político para mejorar la situación de los líderes sociales y defensores de derechos humanos en Colombia. La metodología empleada se basa en la consulta de fuentes que permitan comprender la importancia de la noción de pluralismo y del papel que cumplen los defensores de derechos. No solo se debe hablar de la existencia de los derechos para la interpretación jurídica, sino que también se debe contemplar la promoción de estos. Finalmente, se concluye que el Sistema Integral de Seguridad para el Ejercicio de la Política se debe fortalecer y enlazar con las distintas instituciones del Estado para crear una estructura coordinada que garantice la protección de los líderes sociales, de sus labores y el restablecimiento de sus derechos.
Aportes críticos para una mirada a la salud y seguridad en el trabajo
Authors: Carreño Hernández Ismael E. , Riaño Peña Camilo A.
Published: September 2023

El presente artículo pretende resaltar la importancia que ha tenido el desarrollo de la categoría seguridad y salud en el trabajo como elemento indispensable para la dignidad humana, análisis hecho desde el pensamiento crítico con aportes provenientes de disciplinas diferentes al derecho buscando un soporte interdisciplinar para la defensa de su formulación y realización como derecho fundamental. Se parte del recuento del proceso de formación de las sociedades, en particular la colombiana, en torno al trabajo y la ocupación laboral; luego se muestra la influencia que tuvo la explosión de costos asociados a problemas de los trabajadores en el cumplimiento de sus funciones en términos de productividad, para lo cual han sido determinantes los procesos sindicales; para finalizar se expone el nacimiento de los trabajos en pro de los trabajadores, lugar donde surge la categoría analizada. Como cierre se presentan algunas observaciones generales que pretenden centrar el análisis realizado en algunos aspectos concretos.
Direct Electability, Competence and Responsibility as the Basis for the Long-Term Development of Local Self-Government in Russia
Authors: Kozhevnikov O. A.
Published: September 2023

The issues of legal regulation of local self-government in the Russian Federation have been the subjects of numerous studies and discussions for a long time, while their intensity and relevance not only does not decrease, but also increases from year to year. In many ways, this is due to the fact that over the 30-year period of modern Russian history, the legislation on local self-government and its law enforcement practice is characterized by an extreme degree of dynamism and uncertainty, which certainly affects the quality of organization and functioning of this level of public authority. The meeting of the Council for the Development of Local Self-Government under the President of the Russian Federation, held on April 20, 2023, once again showed the existence of issues and the need for the authorities to find the optimal model of regulatory regulation of municipal government and the extreme imperfection of the provisions of draft law No. 40361-8 “On the general principles of the organization of local self-government in a unified system of public power”, which undoubtedly causes the need for scientific understanding and development of relevant proposals. Based on the historical and legal analysis of the development of the provisions of federal legislation on local self-government, the established constitutional and legal judicial practice, the experience of direct professional activity in local self-government bodies, the Author concludes that the federal legislator over the past 30 years of the existence of local self-government in our state has not only failed to definitively determine the basic legal provisions of the foundations local self-government, constantly “ranking” them and changing them, but it also significantly modified the originally laid down constitutional and legal essence of local self-government as a form of direct participation of citizens in solving issues of the territory of their residence. In this regard, the Author of the study suggests several “fundamental” provisions that will allow us to return to the constitutional and legal format of local self-government, laid down in the early 1990s. It seems that taking into account and consolidating the proposed foundations in the formation of a promising legal regulation of local self-government within the framework of building a unified system of public authority in our state will not only eliminate obvious “excesses” in the current system of legal regulation, but also fully provide a basis for effective interaction of bodies of a unified system of public authority in the interests of the population of the relevant territory.
Peran Bahasa dalam Konstruksi Hukum di Indonesia
Authors: Abdillah Kudrat , Moh Faridi  , Lian fawahan
Published: September 2023

Peranan bahasa dalan konstruksi hukum memiliki makna yang sangat penting dalam perumusan norma-norma perundang-undangan di Indonesia. Ilmu hukum adalah ilmu pengetahuan yang berusaha menelaah tentang hukum yang ada, oleh karenanya ilmu hukum memiliki cara dangan mengunakan logikanya sendiri, yaitu logika hukum dan untuk kebutuhan, kepentingan keberfungsian keilmuannya baik bidang akademik maupun bidang praktis. Rumusan masalah yang akan diteliti adalah meliputi bagaimana peran bahasa dalam rekonstruksi hukum di Indonesia dan bagaimana seharusnya bahasa berperan dalam rekonstruksi hukum di Indonesia. Dalam artikel menekankan pada studi rancangan perundang-undangan. Dari studi ini dapat disimpulkan bahwa hukum memiliki bahasanya sendiri yang tidak sama dengan bahasa pada umumnya, yaitu bahasa hukum yang merupakan hadil dari rekonstruksi hukum itu sendiri. Ilmu hukum dengan segala stratifikasi keilmuannya dan struktur atau klasifikasi hukumnya beserta segala elemen-elemen pendukung sistemnnya sarat dengan bahasa-bahasa hukum yang mengandung artikulasi karakteristik sebagai bahasa keilmuan hukum dan praksis, sehingga untuk memahami disiplin keilmuannya dengan baik, maka harus menggunakan bahasanya sendiri yaitu bahasa hukum.
Apresiasi Negara Terhadap Penyelesaian HAK Asuh Anak Melalui Mediasi
Authors: Faisal Nor , Abdul Hamid Bashori
Published: September 2023

Indonesia sebagai suatu negara yang berdaulat memliki kewajiban untuk melindungi segenap bangsa Indonesia sebagaimana yang diamanatkan oleh UUD NR Indonesia. Salah satu wujud dari perlindungan tersebut adalah keluarnya serangkaian aturan-aturan berkenaan dengan hak asuh anak untuk pasangan yang terjadi pertikaian akiat perceraian.  Tujuan penelitian ini adalah untuk mengungkap bagaimana apresiasi dan konstribusi negara terhadap penyelesaian hak asuh anak melalu mediasi. Penelitian ini menggunakan penekatan kualitatif dengan jenis penelitian library research di mana sumber data akan banyak diperoleh dari berbagai artikel, buku, dan kepustakaan lainnya. Hasil penelitian ini menunjukkan bahwa negara memliki kontribusi besar di dalam memberikan perlindungan kepada anak yang orang tuanya mengalami perceraian. Hak asuh anak sebagaimana yang dikelaskan oleh KHI dan UUP 1974), dimana hak asuh anak yang berumur di bawah 12 tahun (belum mumayyiz) adalah hak dari seorang Ibu selama seorang ibu tersebut patuh dan tunduk kepada aturan syariat dan peraturan perundang-undangan. Namun demikian, negara masih memerikan celah untuk dapat menyelesaikan persoalan tersebut melalui mediasi yang dilakukan antara ke-dua belah pihak. Di samping itu, lahirnya Peraturan Mahkamah Agung Nomor 1 Tahun 2016 dapat dijadikan sebagai rujukan dalam pelaksanaan mediasi di Pengadilan. Peraturan ini sekaligus menunjukkan bahwa negara hadir dan memberikan apresiasi sebesar-besarnya terhadap upaya pengelesaian sengketa hak asuh anak melalui proses mediasi
Pembaruan Hukum Perluasan Kewenangan DKPP dalam Penyelengaraan Pemilu di Indonesia
Authors: Alfarizi Muchlisin
Published: September 2023

Jurnal ini membahas tentang “Pembaruan Hukum Kewenangan DKPP Dalam Penyelenggaraan Pemilu Di Indonesia”. DKPP merupakan salah satu Lembaga penyelenggara Pemilu. Perihal pelaksanaan kewenangan yang dimiliki oleh DKPP masih terjadi problem. Hal ini disebabkan tidak adanya parameter yang cukup jelas untuk dapat digunakan oleh DKPP dalam menangani pelanggaran kode etik penyelenggara Pemilu. Pada dasarnya penanganan yang terjadi di DKPP berdasarkan keadilan restoratif. Di samping itu, seharusnya putusan DKPP bersifat rekomendasi dan tidak bersifat inal and binding. Karena menimbulkan efek psikologis bagi jajaran KPU serta Bawaslu berupa ketakutan akan sanksi pemecatan atau pemberhentian sementara, serta berpotensi menimbulkan polemik Hukum yang berkepanjangan. Dalam penelitian ini menggunakan penelitian Hukum normatif dengan pendekatan statute approach yaitu pendekatan perundang-undangan. Hipotesa singkat dari jurnal ini yaitu DKPP seharusnya diberikan kewenangan yang lebih proporsional dan tidak ada keterkaitan dengan institusi lain sehingga terwujudnya Pemilu yang jujur dan adil.
Status Keabsahan Anak Luar Kawin Pasca Putusan MK NO 46/PUU-VIII/2010
Authors: Moh. Sa'i Affan  , Siti Aisyah
Published: September 2023

Anak merupakan seseorang yang dilahirkan dari hasil hubungan intim antara seorang perempuan dengan seorang laki-laki, dengan adanya pernikahan atau tanpa pernikahan terlebih dahulu. Penelitian ini mengkaji status keabsahan anak luar kawin, beserta keabsahan perkawinan dalam Hukum Positif dan Hukum Islam. Penelitian ini merupakan penelitian yuridis normatif dengan menggunakan data bahan hukum primer dan bahan hukum sekunder. Teknik pengumpulan data melalui penelitian kepustakaan (library research) yang mengatur tentang status anak luar kawin serta keabsahan perkawinan. Hasil penelitian menyimpulkan bahwa anak luar kawin dalam Hukum Positif status keabsahannya menjadi anak tidak sah yang tidak mempunyai hubungan nasab dengan ayahnya. Sedangkan anak luar kawin dalam Hukum Islam merupakan anak hasil zina atau anak mualanah, status nasab hanya kepada ibunya. Dalam Putusan MK No 46/PUU-VIII/2010 anak luar kawin dari hasil perkawinan sirri bisa mendapat hubungan perdata dengan ayahnya, melalui ilmu pengetahuan dan teknologi yang dapat dibuktikan menurut hukum mempunyai hubungan darah antara anak dengan bapak kandungnya. Dalam Hukum Islam anak luar kawin akibat hukumnya tidak mempunyai nasab terhadap bapaknya tidak bisa saling mewarisi.
The Metaverse and Terrorism: Threats and Challenges
Authors: Weimann Gabriele , Dimant Roy
Published: September 2023

The metaverse is currently the leading hype in the digital world because of its seemingly infinite potential and possibilities. Large corporations are drawn to the metaverse because it appears as the cutting edge of digital and technological developments. The metaverse is presented by communication technology companies as the next Internet, a leap towards a universe of boundless, interconnected virtual communities. However, there are many potential risks and challenges that the metaverse raises, including technical, legal, security, business, tax, privacy, security, and users’ well-being and safety (among many others). Cyber-savvy terrorists have been highly resourceful in adapting and applying online platforms and have taken advantage of every new development, platform, and application. Based on their past record, it is reasonable to assume that the metaverse is a new dimension that terrorists and violent extremists are poised to study, examine, and possibly utilise. This research note explores some potential uses of the metaverse by terrorists and suggests preemptive measures to minimise the risks of them doing so. If the advancement of the metaverse or similar developments is inevitable, we should consider risks and abuses and think more carefully about them when moving forward.
Profiles of Individual Radicalisation in Australia (PIRA): Introducing an Australian Open-Source Extremist
Authors: Belton Emma , Cherney Adrian , Zahnow Renee
Published: September 2023

The Profiles of Individual Radicalisation in Australia (PIRA) database captures information on individuals, residing in Australia, who have radicalised to extremism and engaged in a variety of violent and nonviolent ideologically motivated behaviours. Using open-source data, PIRA comprises demographical, individual background, and contextual information and closely replicates the Profiles of Individual Radicalisation in the United States (PIRUS) database. PIRA aims to support research on pathways towards violent extremism and identify background characteristics and risk factors associated with radicalisation. This article seeks to introduce PIRA and provide an overview of its development and coding method, provides a snapshot of the backgrounds, profiles, and risk factors associated with individual radicalisation within the PIRA sample, and briefly compares these findings to existing research. Finally, future research and applications of PIRA are discussed.
Public Health Crisis and Hate Crimes: Deciphering the Proliferation of Anti-Asian Violence in the US Before and During Covid-19
Authors: Liu Mengyan , Anastasio Natalie , LeFreniere Hope , Perliger Arie
Published: September 2023

The substantial increase in far-right violence in the United States in the last few years was also manifested by the intensification of attacks against Asian American communities and individuals. This trend was especially evident during the spread of the COVID-19 pandemic. The current paper utilises a natural experimental design and a multitude of analyses (descriptive, geospatial, and advanced regressions) to illustrate the intricate combination of factors that facilitated anti-Asian violence during the pandemic and the various paths in which public health crises may enhance the persecution of minorities. The findings illustrate that the main drivers of anti-Asian violence are not related to changing focus among organised hate groups, but to environmental and economic stress factors which combine with existing xenophobic narratives, have legitimised anti-Asian violence. Additionally, we identified a clear association between othering rhetoric, also operationalised by President’s Trump kung flu remarks and the subsequent increase in anti-Asian violence. Overall, our findings provide important insights into our understanding of the endogenous and exogenous factors that facilitate hate-related violence against minorities during public health crises.
Um pássaro de papel
Authors: Souza Gustavo Ramos de
Published: September 2023

Publicado em 2017, O peso do pássaro morto, de Aline Bei, rapidamente se tornou um fenômeno de vendas, além de ter chamado a atenção da crítica e se tornado objeto de artigos acadêmicos. O romance conta a história de uma mulher dos 8 aos 52 anos que, durante a sua vida, experimenta inúmeras perdas e sofre com o trauma da violência sexual. Além dos temas tratados, o que chama a atenção é a maneira como, no plano formal, o romance é constantemente atravessado por certo lirismo, podendo ser definido como um romance lírico. Nesse sentido, o artigo pretende analisar O peso do pássaro morto a fim de demonstrar em que medida o gênero lírico reveste a narrativa e como as materialidades do livro – os paratextos, a tipografia, o uso do itálico etc. – concorrem para informar tal lirismo. Para tanto, os aportes teóricos são buscados principalmente nos estudos sobre o romance lírico e sobre as materialidades da literatura.
Sobre Deus, a solitude e o caminho
Authors: Nathanailidis Andressa
Published: September 2023

O artigo apresenta um estudo acerca da correspondência enviada pelo compositor José Antônio de Almeida Prado (1943-2010) para a escritora Hilda Hilst (1930-2004). São abordadas seis correspondências sobre a elaboração e recepção de Pequenos Funerais Cantantes ao poeta Carlos Maria de Araújo, cantata concebida a partir do poema homônimo de Hilst, em homenagem ao poeta Carlos Maria de Araújo. A pesquisa baseou-se no levantamento documental e revisão bibliográfica. Tem o objetivo de promover o resgate documental necessário ao registro histórico-mnemônico referente aos supracitados artistas e suas produções; além de apresentar uma leitura crítica acerca deste material. As cartas transcritas neste estudo, em seus originais, se encontram no Centro de Documentação “Alexandre Eulálio”, do Instituto de Estudos da Linguagem da Universidade Estadual de Campinas (CEDAE/ IEL/ Unicamp). Para viabilizar a pesquisa, optou-se por uma abordagem teórico-metodológica inicial acerca da escrita de si e das correspondências. Dentre os autores presentes estão: Michel Foucault (1992); Silviano Santiago (2006) e Elizabeth Duque-Estrada (2009).
O engenheiro e sua constituição como docente
Authors: Ferreira Debora Meyhofer , Nacarato Adair Mendes
Published: September 2023

Introdução: O professor que atua no ensino Superior, na maioria das vezes, vem de um curso de bacharelado ou pós-graduação no campo específico de trabalho, sem uma formação didático-pedagógica para a docência. Esse é o caso da maioria dos cursos de Engenharia. Objetivo: assim, o objetivo deste estudo é realizar um estado da arte sobre o que tem sido pesquisado, no Brasil, em relação à constituição pedagógica desse engenheiro de formação que assume a docência. Metodologia: Para o mapeamento das pesquisas utilizou-se o Banco de Teses e Dissertações da Capes e da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Essa busca, sem restrição temporal, identificou 17 trabalhos acadêmicos (14 dissertações de mestrado e 3 teses de doutorado) sobre o exercício da docência por engenheiros, distribuídos entre os anos de 2001 e 2019. Resultados: Como resultado, destacaram-se quatro categorias nos trabalhos analisados: a existência (ou não) de uma formação específica para o engenheiro-professor, a identidade do engenheiro-professor, os saberes docentes na engenharia e ainda uma breve discussão sobre ser engenheiro-professor ou professor-engenheiro. Conclusão: além de haver uma crescente quantidade de pesquisas a cada ano, estas revelam uma preocupação também progressiva com a formação desse profissional docente.
O sistema UAB e a universidade flexível
Authors: Kato Fabíola Bouth Grello , Alves Amanda Oliveira de Almeida
Published: September 2023

Introdução: A oferta de cursos de graduação a distância, por meio do sistema Universidade Aberta do Brasil (UAB) nas Instituições Públicas de Ensino Superior (IPES), produz alterações na organização institucional das universidades, que repercutem fortemente na flexibilização do tripé ensino-pesquisa-extensão. Objetivo: Nesse sentido, este artigo busca investigar a inserção da UAB na Universidade Federal do Pará (UFPA) e as repercussões desse sistema no tocante à formação universitária. Metodologia: A pesquisa é de abordagem qualitativa, utilizou-se a pesquisa documental para a análise dos dados. Os dados foram coletados em documentos oficiais publicados pela UFPA, quais sejam: os Projetos Pedagógicos dos seus cursos EAD e editais de programas, bolsas e auxílios, presentes no site do Sistema Gerencial de Assistência Estudantil (SIGAEST), no período de 2013 a 2022. Resultados: Os resultados das análises revelam o enfraquecimento do tripé ensino-pesquisa-extensão no âmbito da oferta de cursos de graduação EAD/UAB, dado que os Projetos Pedagógicos não estão em consonância com as resoluções da UFPA que regulamentam a pesquisa e a extensão. Além disso, os estudantes da EAD/UAB não são contemplados em diferentes editais de assistência estudantil publicados pela universidade, pois os editais analisados destacam que é permitida somente a participação dos estudantes dos cursos regulares presenciais da instituição. Conclusão: Conclui-se que a incorporação da EAD pelas IPES, via sistema UAB, causa a flexibilização das estruturas acadêmicas, o que pode impactar no processo de ensino e aprendizagem da universidade pública, promovendo o esvaziamento da formação.
Mediating Effect of Job Burnout and Self-efficacy between Supervision and Job Satisfaction of Social Workers in Senior Welfare Centers
Authors:   The Association of Korea Counseling Psychology Education Welfare, LEE Byoung-Rock
Published: September 2023

This study performed an analysis of mediating effect of job burnout and self-efficacy betweensupervision and job satisfaction of social workers in senior welfare centers. A survey wasconducted on 291 social workers working at 19 senior welfare centers in Daejeon andChungcheongnam-do from January 3 to 28, 2022. The collected questionnaires were analyzedusing SPSS and AMOS 18.0 program, and main analysis methods were confirmatory factoranalysis and bootstrap test. The analysis results are as follows: First, social workers’ supervisionhad an effect on job satisfaction. Second, mediating effect of job burnout and self-efficacy wasverified in the relationship. Some measures were suggested to improve the job satisfaction ofsocial workers in the centers and to raise the level of leisure services.
Les organoïdes intestinaux des animaux de rente : de nouveaux modèles de culture in vitro pour une meilleure compréhension du fonctionnement de l’intestin
Authors: WIEDEMANN Agnès , LACROIX-LAMANDÉ Sonia
Published: September 2023

L’intestin est un organe complexe aux fonctions multiples. En effet, il participe à la digestion et l'absorption des nutriments et protège l’individu des agressions par des agents pathogènes intestinaux en assurant un rôle de barrière. L’étude de ce compartiment digestif reste toutefois limitée par l’accès aux tissus que ce soit chez l’Homme ou l’animal. Dans ce contexte, le développement d’organoïdes intestinaux à partir de cellules souches représente une avancée technologique importante dans l’étude de la physiopathologie intestinale. De plus, cet outil permet de répondre à une demande sociétale visant à réduire l’usage d’animaux modèles pour la recherche et s’inscrit dans la démarche des 3Rs (Remplacement, Réduction et Raffinement).L’objectif de cette revue est, à partir de rappels de la fonction digestive, de faire un état des lieux sur les différents types d’organoïdes intestinaux existants dérivés d’animaux de rente et de discuter leurs avantages, leurs limites et surtout leur application.
Tales Through a Cultural Lens: Exploring the Global Significance of Cinderella, Snow White, and Sleeping Beauty
Authors: Eslit Edgar R.
Published: September 2023

This article explores the cross-cultural significance of three iconic fairy tales: Cinderella, Snow White, and Sleeping Beauty. Using a comparative analysis approach, the study investigates recurring themes, motifs, and symbolism found in these tales across different cultures and time periods. The research draws on primary and secondary sources such as literary works and scholarly articles to uncover the underlying messages that resonate with audiences worldwide. The historical and cultural contexts of the tales are also examined to provide a deeper understanding of their significance in shaping cultural identity and values. The findings of the research demonstrate the enduring legacy of these tales and their continued relevance in contemporary society. The study highlights how the tales have evolved and adapted over time to reflect changing cultural values and beliefs. The interpretation of the findings offers insights into the role of storytelling in shaping cultural identity and values, and the ways in which these stories continue to inspire and captivate audiences worldwide. Overall, this research provides a comprehensive and nuanced understanding of the significance of these three fairy tales across cultures and time. By illuminating the similarities and differences in these tales, the study offers a fresh perspective on the power of storytelling and its ability to transcend cultural boundaries. The research contributes to the fields of folklore, cultural studies, and cross-cultural communication, inspiring further exploration into the captivating world of fairy tales.
Continuum Mapping and S-Base Space Solution to Coin Weighing Problem
Authors: Chen Lizichen
Published: September 2023

A problem involving the government's inspection of coins in Lower Slobbovia is discussed in the \emph{American Mathematical Monthly}. It is desirable to classify and correct counterfeit coins by utilizing the fewest possible measures. However, previous article only proves the existence of the solution, which does not give a practical solution to the problem. This note provides effective methods to achieve the identification of coiners using dirac delta function and singularity function. Moreover, unit-order construction of continuum mappings and discretization of unique basis vectors with semi-expansion are established in S-base space.
Recent Advances in the Catalytic Conversion of Methane to Methanol: From the Challenges of Traditional Catalysts to the Use of Nanomaterials and Metal-Organic Frameworks
Authors: Vali Alireza , Markeb Ahmad Abo , Moral-Vico Javier , Font Xavier , Sánchez Antoni
Published: September 2023

Methane and carbon dioxide are the main contributors to global warming, being the methane effect twenty-five times more powerful than carbon dioxide. Although the sources of methane are diverse, it is a very volatile and explosive gas. One way to store the energy content of methane is its conversion to methanol. Methanol is liquid under ambient conditions, easy to transport and, apart from its use as an energy source, it is a chemical platform that can serve as a starting material for the production of various higher value-added products. Accordingly, the transformation of methane to methanol has been extensively treated in the literature, using traditional catalysts as different types of zeolites. However, in the last years, a new generation of catalysts have emerged to carry out this transformation with higher conversion and selectivity, and more importantly, under mild temperature and pressure conditions. These new catalysts typically involve the use of a highly porous supporting material such as zeolite, or more recently, metal-organic frameworks (MOFs) and graphene, and metallic nanoparticles or a combination of different types of nanoparticles that are the core of the catalytic process. In this review, the characteristics, the catalytic mechanisms, reactors, and the main results of these catalysts are presented as a way to overcome the challenges found in traditional catalysts.
Automatic Diagnosis of Epileptic Seizures using Entropy-based Features and Multimodel Deep Learning Approaches
Authors: Al-Qazzaz Noor , Alrahhal Maher , Jaafer Sumai , Ali Sawal , Ahmad Siti
Published: September 2023

One of the most prevalent brain diseases, epilepsy is characterized by recurring seizures that happen quite frequently. During seizures, a patient suffers uncontrollable muscle contractions that cause loss of motion and balance, which could lead to harm or even death. Establishing an automatic method for warning patients about impending seizures requires extensive research. It is possible to anticipate seizures by analyzing the Electroencephalogram (EEG) signal from the scalp region of the human brain. Time domain-based features such as Hurst exponent (Hur), Tsallis Entropy (TsEn), improved permutation entropy (impe), and amplitude-aware permutation entropy (AAPE) were extracted from EEG signals. In order to diagnose epileptic seizure children from normal children automatically, this study conducted two sessions, in the first session, the extracted features from the EEG dataset were classified using three machine learning (ML)-based models including support vector machine (SVM), K nearest neighbor (KNN), or decision tree (DT), while in the second session, the dataset was classified using three deep learning (DL)-based recurrent neural network (RNN) classifiers including a gated recurrent unit (GRU), long short-term memory (LSTM), and bidirectional (BiLSTM). The EEG dataset obtained from the Neurology Clinic at the Ibn-Rushd Training Hospital. In this regard, detailed explanations and research from the time domain and entropy characteristics show that using GRU, LSTM, and BiLSTM RNN deep learning classifiers on the All−time−entropy fusion feature improves the final classification results.
Nuclear Medicine and Cancer Theragnostics
Authors: Zoi Vasiliki , Giannakopoulou Maria , Alexiou George A , Bouziotis Pinelopi , Thalasselis Savvas , Tzakos Andreas G , Fotopoulos Andreas , Kyritsis Athanassios P , Sioka Chrissa
Published: September 2023

Cancer theragnostics is a novel approach that combines diagnostic imaging and radionuclide therapy. It is based on the use of a pair of radiopharmaceuticals, one optimized for positron emission tomography imaging, through linkage to a proper radionuclide, and the other bearing a beta-emitter isotope that can induce significant damage to cancer cells. In recent years, the use of theragnostics in nuclear medicine clinical practice has increased considerably, and thus investigation has focused on the identification of novel radionuclides that can bind to molecular targets which are typically dysregulated in different cancers. The major advantages of the theragnostic approach include elimination of multi-step procedures, reduced adverse effects to normal tissues, early diagnosis, better predicting responses and personalized patient care. This review aims to discuss emerging theragnostic molecules that have been investigated in a series of human malignancies, including gliomas, thyroid cancer, neuroendocrine tumors, cholangiocarcinoma and prostate cancer, as well as potent and recently introduced molecular targets, like cell-surface receptors, kinases, and cell adhesion proteins. Furthermore, special reference has been made to copper radionuclides as theragnostic agents, and their radiopharmaceutical applications since they present promising alternatives to the well-studied gallium-68 and lutetium-177.
DUBing Primary Tumors of the Central Nervous System: Regulatory Roles of Deubiquitinases
Authors: Klonisch Thomas , Logue Susan E. , Hombach-Klonisch Sabine , Vriend Jerry
Published: September 2023

The ubiquitin proteasome system (UPS) utilizes an orchestrated enzymatic cascade of E1, E2, and E3 ligases to add single or multiple ubiquitin-like molecules as post-translational modification (PTM) to proteins. Ubiquitination can alter protein functions and/ or marks ubiquitinated proteins for proteasomal degradation but deubiquitinases (DUBs) can reverse protein ubiquitination. While the importance of DUBs as regulatory factors in the UPS is undisputed, many questions remain on DUB selectivity for protein targeting, their mechanism of action, and the impact of DUBs on the regulation of diverse biological processes. Furthermore, little is known about the expression and role of DUBs in tumors of the human central nervous system (CNS). In this comprehensive review, we have used publicly available transcriptional datasets to determine the gene expression profiles of 99 deubiquitinases (DUBs) from five major DUB families in seven primary pediatric and adult CNS tumor entities. Our analysis identified selected DUBs as potential new functional players and biomarkers with prognostic value in specific subtypes of primary CNS tumors. Collectively, our analysis highlights an emerging role for DUBs in regulating CNS tumor cell biology and offers a rationale for future therapeutic targeting of DUBs in CNS tumors.
Roof Structure Extraction from Aerial Images and nDSM using Deep Learning
Authors: Kenzhebay Meruyert , Zhao Wufan , Koeva Mila , Persello Claudio
Published: September 2023

A topic of growing interest in urban remote sensing is the automated extraction of geometrical building information for 3D city modeling. Roof geometry information is useful for applications such as urban planning, solar potential estimation and telecommunication installation planning, and wind flow simulations for pollutant diffusion analysis. Recent research has proven that the advance in remote sensing technologies and deep learning methods offer the prospects of deriving the roof structure information accurately and efficiently. In this study, we propose a Vectorized Roof Extractor- method based on Fully Convolutional Networks (FCNs) and advanced polygonization method to extract roof structure from aerial imagery and a normalized Digital Surface Models (nDSM) in a regularized vector format. The roof structure consists of building outlines, external edges of the building roof, inner rooflines, internal intersections of the main roof planes. The methodology is comprised of segmentation, vectorization and post-processing for outer rooflines, external edges of the building roof, and inner rooflines, and internal intersections of the main roof planes. For the comparison, we adapt the Frame field Learning (FFL) method originally designed to extract building polygons [1]. Our experiments are conducted on a custom data set derived for the city of Enschede, The Netherlands, using aerial imagery, nDSM and manually digitized training polygons. The results show that the proposed Vectorized Roof Extractor outperformed adapted FFL on PoLiS distance with values of 3.5 m and 1.2 m for outlines and inner rooflines, respectively. Furthermore, the model surpassed the adapted FFL on PoLiS-thresholded F-score for outlines and inner rooflines, with 0.31 and 0.57, respectively. The Vectorized Roof Extractor produced adequate visual results, with straighter walls and fewer missed inner roofline detections. It can predict buildings with common walls thanks to skeleton graph computation. To summarize, the proposed method is suitable for urban applications and has the potential to be improved further.
Effect of a Multi-Strain Probiotic on Growth Performance, Lipid Profile, Antioxidant Status and Immune Response in Piglets at Weaning
Authors: Sarkar Gopal , Mondal Samiran , Bhattacharya Debasis , Ponraj Perumal , Sawhney Sneha , De Arun Kumar
Published: September 2023

The study investigated the effect of a multi-strain probiotic compound containing Bacillus coagulans, Enterococcus faecalis, Clostridium butyricum and Bacillus mesentericus as in-feed zinc oxide (ZnO) alterna-tive on growth performance, diarrhea incidence, antioxidant status, lipid profile, stress and immunity in weaned piglets. A total of 72 piglets were randomly divided into 3 groups with four replicates of six piglets each. The details of the groups were as follows; (i) weaned control group (WC) received basal diet, (ii) weaned probiotic group (WB) received basal diet and probiotics and (iii) positive control (PC) group received basal diet with 2500 mg/kg ZnO. The experiment lasted for 28 days. Probiotic supple-mentation improved growth performance and reduced diarrhea rate. Probiotics supplementation im-proved lipid profile; significantly lower levels of total cholesterol and low-density lipoprotein cholesterol and higher level of high-density lipoprotein cholesterol in WB group as compared to those of the control group (WC) were recorded. Probiotic supplementation stimulated antioxidant defense system by in-creasing total antioxidant capacity and decreasing lipid peroxidation. Probiotic supplementation down-regulated the stress biomarkers like serum cortisol and serum heat shock proteins. WB group showed higher serum levels of IgG and IgM throughout the study period and higher IgA at day 28 as compared to WC. These data suggest that supplementation of the probiotic minimizes the weaning stress, thereby improves the growth performance, lipid profile, antioxidant status and systemic as well as mucosal immunity. Therefore, the multi-strain probiotic compound may be used to replace ZnO in weaned piglets.
Vestibular Drop Attack: An Analysis of the Therapeutic Response
Authors: Carmona Sergio , Fernandez Martin Gabriel , Espona Cristian David
Published: September 2023

The present study evaluates the response to betahistine in patients who presented vestibular drops attacks in the context of Ménière's disease (MD) and the factors that can predict an unfavorable response to it. A total of 43 patients were analyzed, out of which 33 were diagnosed with MD. It is a descriptive, cross-sectional study with retrospective data collection. Data as regards age, accompanying symptoms, etiological diagnosis and response to MD treatment were collected. A statistical analysis was carried out, and we found that the disease evolution time and specific alterations in the vestibulospinal and oculomotor physical examination present an unfavorable response to betahistine, as opposed to the use of intratympanic gentamicin, with which symptomatic control is achieved in 100% of the cases.