bluuebunny/crossref_metadata_2025 huggingface dataset:
A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection
Authors: Wu Po-Chang , Pai Chao-Ping , Lee Mon-Juan , Lee Wei
Published: October 2021

A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10−5 g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10−7 g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10−8 g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10−8 g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay.
The Association of Job and Family Resources and Demands with Life Satisfaction through Work–Family Balance: A Longitudinal Study among Italian Schoolteachers during the COVID-19 Pandemic
Authors: Landolfi Alfonso , Barattucci Massimiliano , De Rosa Assunta , Lo Presti Alessandro
Published: October 2021

Successfully balancing between work and family domains represents a major issue to both employees and employers, especially during COVID-19 pandemic times during which employees are often forced to work from a distance and turn to home-schooling. An occupational group particularly affected by work changes due to COVID-19 pandemic restrictions is represented by schoolteachers. We aimed at examining the associations between some job-related and family-related antecedents on the one hand and, on the other, life satisfaction as an outcome, including work–family balance as a mediator. A total of 357 Italian teachers completed a questionnaire at two different times: job control, coworkers support, supervisor support, workload, family support, and family workload were assessed at Time 1; and work–family balance and life satisfaction were assessed at Time 2. Both data collections were performed during the COVID-19 pandemic. The hypothesized direct and indirect relationships were tested by utilizing structural equation modeling. Significant and positive indirect effects of focal predictors towards life satisfaction through work–family balance were found for job control, supervisor support, and family support. The paper contributed to the literature by testing Grzywacz and Carlson’s theoretical conceptualization of work–family balance and by attempting to delineate its repertoire of potential antecedents among schoolteachers. From a practical point of view, the present study emphasizes the crucial role that certain job antecedents and family antecedents play in promoting teachers’ work–family balance and life satisfaction.
Real World Outcomes in Patients with Advanced Melanoma Treated in Alberta, Canada: A Time-Era Based Analysis
Authors: Rigo Rodrigo , Doherty Jordan , Koczka Kim , Kong Shiying , Ding Philip Q. , Cheng Tina , Cheung Winson Y. , Monzon Jose G.
Published: October 2021

Immune checkpoint and MAP kinase pathway inhibitors can significantly improve long-term survival for patients with melanoma. There is limited real-world data of these regimens’ effectiveness. We retrospectively analyzed 402 patients with unresectable and metastatic melanoma between August 2013 and July 2020 treated with immune checkpoint inhibitors and MAP kinase pathway targeted therapy in Alberta, Canada. Overall survival (OS) was compared using Kaplan–Meier and Cox regression analyses. Subgroup survival outcomes were analyzed by first-line treatment regime and BRAF mutation status. Three treatment eras were defined based on drug access: prior to August 2013, August 2013 to November 2016, and November 2016 to July 2020. Across each era, there were improvements in median OS: 11.7 months, 15.9 months, and 33.6 months, respectively. Patients with BRAF mutant melanoma had improved median OS when they were treated with immunotherapy in the first line as opposed to targeted therapy (median OS not reached for immunotherapy versus 17.4 months with targeted treatment). Patients with BRAF wild-type melanomas had improved survival with ipilimumab and nivolumab versus those treated with a single-agent PD-1 inhibitor (median OS not reached and 21.2 months). Our real-world analysis confirms significant survival improvements with each subsequent introduction of novel therapies for advanced melanoma.
Road Freight Company: Improving Efficiency and Work Prospects
Authors: Chernyakin A.M. , Bykova O. N.
Published: October 2021

The transport and logistics industry is an important component of any economy. It serves the vast majority of other industries of a production and non-production nature, provides transportation of goods between all participants in economic relations throughout the country and around the world. It is safe to say that the state and development of cargo transportation directly depends on changes in the surrounding business environment, namely, not only on legislative regulation, state support and business skills, but also on the state of the clients served.
The specifics of managing the marketing department remotely in the context of COVID-19
Authors: Morozov S.A. , Sidorova V. N.
Published: October 2021

The article discusses the features of personnel management of the marketing department on a remote basis during a pandemic. The analysis of key changes in work, which led to a change in the format of interactions between employees of the marketing department and other divisions, was carried out. The advantages and disadvantages in the functioning of the marketing department with the help of modern corporate online services are determined.
Forecasting and assessment of uncertainty in labor and economic activities of personnel at the enterprise
Authors: Bukhalkov M.I.
Published: October 2021

The complex scientific category «uncertainty» in the labor and economic activities of personnel at enterprises is considered, methodological recommendations and a system of planning and economic indicators aimed at increasing the efficiency of labor and production resources, primarily the labor of personnel and the capital of entrepreneurs, are presented.
Planning and perspective: promoting international companies in the Russian market
Authors: Shevaldova L.A. , Repnikova V.M.
Published: October 2021

The modern market as a sphere of commodity exchange is dynamic, extremely unstable and extremely demanding on companies. The Russian ice cream market is no exception. Due to its maturity and modest growth in consumption, it is on the verge of structural change. Medium-sized manufacturers are more active and strive to take leading positions, niche companies, which promptly respond to the latest trends, are taking increasingly strong positions.
Justification by Race: Wesley Swift’s White Supremacy and Anti-Semitic Theological Views in His Christian Identity Sermons
Authors: Bochicchio Ana
Published: October 2021

This article explores the discourses of Minister Wesley Albert Swift (1913–1970), one of the original and leading proponents of Christian Identity, a racial theology movement which emerged in the United States after World War II. It is not the aim of this study to analyze the discourse of Christian Identity as an isolated element, but to understand its interrelation with the political-religious culture of the country during the 1950s and 1960s. Christian Identity rhetoric may be understood based on its socio-historical context. During the formulative years of Christian Identity, nuclear anxieties, along with the fear of Communist infiltration, were deeply present within the white supremacist and their anti-Semitic views. At the same time, the civil rights movement of African Americans stimulated violent white supremacy politics and rhetoric by the extreme right. Combining the white hegemonic fear of minority advances in American society, Christian Identity was created as a cult for the racist right. As such, it attempted to legitimized white supremacy and perpetuate the Judeo-Communist Conspiracy myth. Race — as a biological issue that reflects the spiritual essence of a person — is the central element of anthropology built by Christian Identity, which claims the white race was literally created in the image of God. Therefore, they argue, it is the only race predestined for salvation. As an expression of an extreme Calvinist world view, Wesley Swift constructed a Christian theology that ideologically unified different political strategies of the postwar extreme right, which continues to this day.
Envy and Resentment in the Time of Coronavirus
Authors: Protasi Sara
Published: October 2021

I examine the role played by the emotions of envy and resentment in interpersonal online dynamics during the COVID19 pandemic. I start by reviewing what we know about the interplay of social media use, social comparison and well-being, and by applying this knowledge to current circumstances. Then, I introduce some philosophical distinctions that complicate the already complex empirical evidence, differentiating, in particular, between envy and resentment, and between different kinds of envy. I argue that we can use the knowledge of these distinctions to better cope with these painful, but sometimes productive and always informative, emotions.
Predictors of Anti-Asian Xenophobia During Covid-19: Towards Developing Targeted Intervention Campaigns
Authors: Lambe Jennifer , Young Dannagal , Bleakley Amy , Crowley John , Silk Kami
Published: October 2021

Anti-Asian xenophobia (AAX) spiked during Covid-19, exacerbating health disparities among affected groups. This study uses data from a national survey to identify predictors of AAX to enable targeting of audience segments and effective messaging to counteract Anti-Asian attitudes and behaviors. Using Intergroup Threat Theory (ITT) to pinpoint possible predictors, we find that situation specific variables such as favorability toward Trump and information seeking and avoidance behaviors consistently predict higher levels of AAX. Individual differences like being female, well-educated, and having a high tolerance for ambiguity are negatively related to AAX.
“It’s not Really Hate Crime” – Reframing Hate Crime as not Police Business” – Police Narratives of Resistance and Denial
Authors: Bryan Timothy , Trickett Lorretta
Published: October 2021

Within a global pandemic and increased questioning of police utility and legitimacy around racism and violence against women and girls (VAWG), this article examines the gap between police policy and practices on hate crime. Based on research with police forces in Canada and the UK, it demonstrates how police officers view hate crime through a policing rather than victim-centred mandate. Without reframing hate crime as a public and community safety issue, hate crime policies and procedures designed to ‘take hate crime seriously’ are unlikely to do just that. Real ‘commitment’ is needed to tackle hate crime as part of the police mandate and role – otherwise hate crime policies remain a largely tick-box exercise.
IMPACT OF COVID-19 ON CONSUMER BEHAVIOUR
Authors: Bisaria Charu
Published: October 2021

A deadly virus has forced entire mankind to be confined to their homes. While many businesses were permanently shut, most others are still trying to sustain this less profit-generating period. Numerous workers are facing pay-cuts or job loss. This theoretically implies a major impact on the economies of countries with purchasing power of customers reduced due to lower income and supply chain disruption due to strict curbs. However, industries based on Information Technology, e-commerce, dairy products etc, thrived and continued to meet consumers’ demands. This particular study aims to analyze the impact of COVID-19 on consumer behavior. The impact shall be studied with respect to various parameters such as gender, age, income etc of consumers.
RECESIÓN ECONÓMICA E IMPACTO EN LA RENTABILIDAD DE LA INDUSTRIA DE LA CONSTRUCCIÓN, ECUADOR 2019 – 2020: EL COVID-19, UN CISNE NEGRO
Authors: Sarmiento Castillo Germania del Pilar , Hernández Ocampo Silvana Elizabeth
Published: October 2021

La investigación refiere la incidencia del COVID – 19 en la rentabilidad del sector de la construcción como un “cisne negro”, entendiéndose como un hecho fortuito, sorpresivo. El COVID-19 ha sido un suceso inesperado e inimaginable para muchos el tener que sobrevivirlo, desencadenó una crisis social, política y económica, pronosticándose importantes caídas del PIB. Este estudio se inició con un análisis descriptivo, de la rentabilidad que obtuvieron las empresas del sector de la construcción, durante los años 2019 y 2020, el análisis inferencial determinó la diferencia del ROA y se utilizó el estadístico Prueba de Wilcoxon para dos grupos relacionados que contrastan hipótesis no paramétricas. Los resultados reflejaron el 4,44% de la media de rentabilidad en las empresas de la construcción durante el año 2019, evidenciando un promedio de ganancias, sin embargo, durante el año 2020, el promedio de utilidades en función de sus activos fue de (-0,32%) es decir las utilidades se contrajeron al punto de establecerse un promedio de pérdidas, reflejando con ello que el COVID -19, generó un impacto negativo en la salud, en la economía y en el caso de sectores específicos como es el de la construcción.
Reading Skill of Elementary School Students and Relationship to Foreign Language (German and Japanese) Contained in The Text
Authors:   Departemen Pendidikan Bahasa dan Sastra, Universitas Pendidikan Indonesia, Indonesia, Diska Mariyandi Danindra , Wibawa Sakti Asri ,   Departemen Pendidikan Kesejahteraan Keluarga, Universitas Pendidikan Indonesia, Indonesia, Wulandary Verra ,   Department of Educational development course, Hiroshima University, Higashihiroshima, Hiroshima, Jepang
Published: October 2021

This study aims to analyze students' interest in foreign languages such as German or Japanese. Descriptive qualitative research method. The data collection technique used descriptive qualitative and gave some reading texts to the children. The results of the study showed that the relationship between students to foreign languages other than the language that was introduced was very high, and they increasingly wanted to learn the foreign language even though they could not pronounce foreign vocabulary correctly, the foreign language contained in the Indonesian text did not make them stop reading or reading.
Technology on E-Payment Systems
Authors:   Departemen Manajemen, Universitas Komputer Indonesia, Indonesia, Soegoto E S , A Rahman R ,   Fakultas Teknik dan Ilmu Komputer, Universitas Komputer Indonesia, Indonesia
Published: October 2021

The purpose of this study is to examine the importance of technology in business, especially in terms of transactions. The method used in this study was a descriptive method by reading from various international and domestic journals. The results of this study were identification of how simple and important technology was in influencing payment systems that were slowly changing from conventional to electronic payments (e-payment). We also discussed what information related to e-payment, such as safety, functions, and available features from using this e-payment system.
Information Technology for Travel Agency
Authors:   Departemen Manajemen, Universitas Komputer Indonesia, Indonesia, S Soegoto E ,   Fakultas Teknik dan Ilmu Komputer, Universitas Komputer Indonesia, Indonesia, H Nugroho A
Published: October 2021

The purposes of this research are to describe, analyze, and determine the online marketing strategy of domestic travel agent at Bandung Tour Expert. In this case, the authors focused on SWOT analysis to find out the right marketing strategy for the tour packaging. In this research, the data was collected using the observation method, meanwhile the data analysis method used were descriptive qualitative and SWOT analysis. Internet users number are increasing, especially adults with high mobility. For them who often travel outside the city, internet is crucial because it connects them with the travel agent. Nowadays, the convenient use of Internet technology is used to market products and services offered by travel agents, so that it provides many benefits for business travel agents with minimum marketing costs. The results of this study were the use of internet and online marketing had impacts on the increasing profits of the travel agents. The conclusion of this research is Bandung Tour Expert as a company need to improve their variant of tour package to make tourist more interest to visit the company website.
Economic Evaluation on the Production of Poly-DADMAC and Sepiolite Nanocomposite
Authors:   Departemen Pendidikan Kimia, Universitas Pendidikan Indonesia, Indonesia, Ayu Rosmawati Dita , Annur Rizqia Azzahra ,   Departemen Pendidikan Kimia, Universitas Pendidikan Indonesia, Indonesia, Jannah Sifathul ,   Departemen Pendidikan Kimia, Universitas Pendidikan Indonesia, Indonesia, Nur Azizah Nissa ,   Departemen Pendidikan Ilmu Komputer, Universitas Pendidikan Indonesia, Indonesia, Bayu Dani Nandiyanto Asep ,   Departemen Pendidikan Kimia, Universitas Pendidikan Indonesia, Indonesia
Published: October 2021

Some agricultural wastes are not suitable for direct disposal to standard sewage treatment plants and pre-treatment is required to avoid clogging by colloidal materials. One of the pre-treatment stages is coagulation and flocculation. In several studies, the mixture of polymer and clay fulfills the properties of coagulant and flocculant materials. A mixture of poly-DADMAC polymer and sepiolite clay can be used as a coagoflocculant at the same time. This study aims to analyze whether a project to manufacture clay polymer nanocomposites is feasible or not. By taking into account various perspectives including engineering and economic perspectives, this project is considered prospective to be carried out. This is indicated by the increase in the Profitability Index (PI) value of 5.33658 in the third year from -0.00975 which was the PI value the previous year. In twenty-four hours, the project can produce approximately 8.25 tonnes of adsorbent. The total profit earned in one year reaches 719,738.04 USD when run under ideal conditions. Apart from the results of the economic analysis mentioned, this project is also very effective in terms of time because it is simple and the raw materials needed are abundant
Techno-Economic Analysis on the Production of Copper Oxide Nanoparticles by Green Synthesis Method using Abultion indicum Leaf Extract on an Industrial Scale
Authors:   Departemen Kimia, Universitas Pendidikan Indonesia, Indonesia, F Putra R , Satari C , S Sidqi R , R Putri S , B D Nandiyanto A
Published: October 2021

The purpose of this study was to evaluate the economic feasibility of producing copper oxide (CuO) nanoparticles using the green synthesis method on an industrial scale for 10 years by evaluating from an engineering and economic perspective. Various economic parameters are used to analyze economic viability, including Gross Profit Margin (GPM), Cumulative Net Present Value (CNPV), Payback Period (PBP), as well as economic variations in sales, taxes, raw materials, labor wages, and utilities to ensure project feasibility. Technical analysis to produce 100 kg of CuO nanoparticles per day requires a total production cost of 220,322.850.00 IDR and the gross profit margin is 16,721,250.000,00 IDR per year. PBP analysis shows that the investment will be profitable after more than three years. This project can compete with PBP capital market standards because of the short investment return. The profit is relatively economical, so this project can be run for 10 years under ideal conditions. This research is expected to be a reference for technical and economic analysis of industrial-scale production of CuO nanoparticles
Techno-Economic Analysis in the Production of Copper Nanoparticles by Biosynthetic Method using Citrus medica Linn. Extract
Authors:   Departemen Pendidikan Kimia, Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam, Universitas Pendidikan Indonesia, Jl. Dr. Setiabudi no. 229, Bandung 40154, Jawa Barat, Indonesia, S Anggiat L , A Fadhilah R , K Insan F , C S Girsang G , B D Nandiyanto A
Published: October 2021

Copper nanoparticles are the most frequently used materials in the field of nanoscience because of their electrical, optical, biomedical, antifungal, and antibacterial properties. The synthesis of copper nanoparticles with biological methods is known to be environmentally friendly, inexpensive, simple, and capable of producing better nanoparticles than other methods. This study aims to determine the feasibility of an industrial project to manufacture Cu nanoparticles through a biosynthetic method using Citrus medica Linn. extract and evaluate it from an engineering and economic point of view. Some of the parameters used for economic evaluation are Payback Period (PBP), Break Even Point (BEP), and Cumulative Net Present Value (CNPV). The analysis is supported using data taken from online shopping websites. The results showed that the number of Cu nanoparticles that could be produced in one year was 24,000 kg. The total initial capital cost is 272,640.00 USD and the profit is 698,655.90 USD/year. PBP occurred in the 3rd year with the CNPV/TIC value reaching 3.746% in the 9th year. Based on the economic evaluation, the project is concluded to be feasible to run with the anticipated tax and percentage of sales. The results of this study are expected to provide an overview of the economic evaluation of industrial-scale Cu nanoparticles production by biosynthetic method using Citrus medica Linn. extract.
Cost Analysis and Economic Evaluation for Manufacturing Hydroxyapatite Nanoparticles from Eggshell Waste
Authors:   Departemen Pendidikan Kimia, Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam, Universitas Pendidikan Indonesia, Jl. Dr. Setiabudi no. 229, Bandung 40154, Jawa Barat, Indonesia, Annisa T , Azkiya A , N Fauzi R , B D Nandiyanto A , Hofifah S N
Published: October 2021

The aim of this study is to evaluate the economic feasibility of manufacturing hydroxyapatite nanoparticles from eggshell waste. The economic analysis perspective is carried out by calculating various economic parameters, namely gross profit margin (GPM), payback period (PBP), break event point (BEP), internal rate return (IRR), creating net present value (CNPV), return on investment ( ROI) and profitability index (PI). The results show that the production of hydroxyapatite nanoparticles from eggshell waste is prospective. Technical analysis to produce 30,150 Kg of hydroxyapatite per year shows the total cost of equipment purchased is Rp. 230,580,000.00, and the total cost of raw materials is Rp. 890,235,720.00. The profit obtained from the sale of the product is Rp. 4,520,803,500.00/year. Within 20 years of the construction of this project, using eggshells as a raw material for production can reduce the accumulation of eggshell waste. This project can compete with PBP capital market standards due to the short return on investment of around 3 years. To ensure feasibility, the project is estimated from ideal to worst case conditions in production, including labor, sales, raw materials, utilities, as well as external conditions (taxes and subsidiaries). The benefits of this research are that it can provide information on the economic feasibility of manufacturing hydroxyapatite nanoparticles on a large scale, and can optimize/develop projects for further investigation.
Translation of German anthroponyms in a novel “Die Abenteuer des Werner Holt” (Book 1) by Dieter Noll: linguistic and cultural aspect
Authors: Bandurko Zinaida , Blazhko Mariia , Liepukhova Nataliia , Kovbasyuk Larysa , Kishchenko Yuliya
Published: October 2021

The article considers the translation of German anthroponyms in a literary text, taking into account the achievements of modern linguistic and cultural studies. The research is based on the theory of precedent and the following research methods: etymological, word-formation analysis, lexical-semantic analysis, analysis of dictionary definitions, linguistic and stylistic analyses etc. To achieve the purpose of scientific research, such an algorithm of actions is applied: 1) establishment of precedent phenomena and surnames, determination of the association to which they appeal; 2) analysis of the method of transferring German surnames in the Ukrainian translation; 3) identification of translation decisions. The study was based on 190 surnames of characters from Dieter Noll’s novel “Die Abenteuer des Werner Holt” (Book 1). The system of surnames of the novel is divided into two groups: precedent and fictional. Precedent onyms denote famous writers, philosophers, generals and others. Fictitious onyms are divided into German surnames, foreign surnames and author’s surnames. German surnames are of German origin. The second group singles out surnames of Slavic origin. Author’s surnames are characterized by a certain connotation and influence on the reader. The reproduction of German surnames in the Ukrainian translation takes place by means of transcription and transliteration.
Realization and restriction of constitutional rights in vaccination against Covid-19
Authors: Harahonych Oleksandr , Homonay Vasyl , Kuznietsova Zoia , Khrapenko Olena , Nazarko Arkadii
Published: October 2021

The democratic community has faced a challenge regarding the existence or absence of a legal basis for the introduction of compulsory vaccination. The scholars asked the question: Is compulsory vaccination against COVID-19 a violation of personal non-property human rights or the implementation by the state of its duty to ensure the sanitary and epidemiological well-being of the entire population and protect society from a deadly disease? Methodology of work: logical-semantic, historical, analytical, extrapolation, comparative legal methods, methods of comparison and generalization, analysis, and synthesis. Results of the study: the assessment of the historical and international experience in the implementation of vaccination was carried out; the negative and positive aspects of mass vaccination were considered; the legal regulation of vaccination was studied; the legal framework in this area was compared; the judicial practice regarding legal relations that arise during vaccination was analyzed. The conclusion is made regarding priority in the context of the increasing spread of COVID-19, the observance of which rights is key during the mandatory mass vaccination (the right to a high-quality, highly effective vaccine, the right to choose a vaccine, equal availability of a vaccine, the right to receive compensation in case of negative consequences after vaccination, etc.).
Discourse analysis and digital technologies: (TikTok, hashtags, Instagram, YouTube): universal and specific aspects in international practice
Authors: Izotova Natalya , Polishchuk Mariia , Taranik-Tkachuk Kateryna
Published: October 2021

Nowadays, digital communication helps people to establish contact quickly and conveniently, to convey their message, ideas, the vision of the world to a wide audience. In this regard, new challenges have emerged for discourse analysis in the field of research on the features of digital communication, digital communication practices, the impact of electronic communication technologies on the formation and conduct of discourse, application, and influence of extralinguistic factors on speech. The article analyzes the problems and features of discourse using digital technologies, current trends, and new data in the field of social networks, hashtag activism, problems of involvement, activity, motivation of participants in online communication, formation of their online identity. The authors used system-functional, hermeneutic methods, linguistic analysis, methods of analysis, and synthesis in the framework of discourse theory. The study found and confirmed that the features of digital communication practices and the formation of discourse on the Internet are the widespread use of social networks, hashtags, social integration activities such as challenges, the use of special vocabulary specific to Internet communication, the ability to express themselves and form their own online user identity. Extralinguistic factors of discourse formation in digital communicative practices are major from the point of view of discourse analysis.
The criminal responsibility for defamation of knowingly innocent
Authors: Navrotska Vira , Bronevytska Oksana , Yaremko Galyna , Maksymovych Roman , Matolych Vita
Published: October 2021

The scientific article analyzes the acute discussion in law enforcement practice and procedural science of the problem of the possibility of criminal prosecution of a suspect, accused of defaming a knowingly innocent person in the commission of a crime. The theoretical basis of the article are scientific works on criminal law and criminal procedural law (both domestic researchers and foreign experts). A set of general scientific, special scientific and philosophical methods of scientific knowledge has been used while preparing the scientific article, in particular dialectical, historical, comparative, dogmatic (formal-logical), system-structural analysis, modeling. It is substantiated in the article that the behavior of the suspect, accused, which is manifested in slandering of a knowingly innocent person, does not constitute the right to freedom from self-disclosure. It is also proved that both freedom from self-disclosure and the right to defense in criminal proceedings must have certain limits, in particular, it is rights and interests of other subjects protected by criminal law. We stated that the suspect or accused should be liable for misleading the court and pre-trial investigation bodies even if such deception was used to protect against the suspicion (or accusation), to avoid criminal liability.
Effectiveness standards for investigation of corruption crimes: Theory and practice
Authors: Ostrohliad Oleksandr , Torbas Oleksandr , Zavtur Viktor , Sydorchuk Vladyslav , Fedoriv Oleh
Published: October 2021

The article deals with development of a doctrinal system of effectiveness standards for the investigation of corruption crimes. The study used a number of philosophical, general scientific and specific methods of gaining scientific knowledge, including: dialectical method, hermeneutic method, method of systemic and structural analysis, methods of analysis and synthesis, functional method, formal legal method and modeling method. It is proposed to define the investigation effectiveness as the feature of pre-trial investigation, which is characterized by the ability to achieve the tasks envisioned in Art. 2 of the CPC of Ukraine (Law No. 4651-VI, 2012) and can be assessed by checking the number of objectively necessary procedural actions and the effectiveness of making intermediate and final procedural decisions. It is emphasized that the general standards of investigation effectiveness, formulated by the case law of the ECHR, are partially taken into account in Art. 2 of the CPC of Ukraine (Law No. 4651-VI, 2012) through stating the need of investigation being efficient, complete and impartial. The authors formulate scientific approaches to determining the main criteria for the effectiveness of pre-trial investigation of corruption crimes.
LEISHMANIOSE VISCERAL CANINA: BREVE REVISÃO E RELATOS DE CASOS
Authors: Paulino da Cruz Vieira Vanessa , Mendes Figueiredo Nathalia
Published: October 2021

A leishmaniose é uma doença causada por um protozoário da espécie Leishmania chagasi. É transmitida pela picada de fêmeas do inseto vetor infectado, um flebotomíneo da espécie Lutzomyia longipalpis, conhecido popularmente como mosquito palha. De ampla distribuição geográfica, o Brasil é responsável por 96% dos casos notificados nas Américas. Trata-se de uma zoonose de evolução crônica, com acometimento sistêmico e, se não tratada, pode levar a óbito até 90% dos casos. No cão, considerado o principal reservatório urbano do agente etiológico, a leishmaniose visceral canina é uma enfermidade que provoca grande sofrimento aos animais acometidos, tutores e contactantes. As manifestações clínicas dependem intrinsecamente do tipo de resposta imunológica apresentada pelo seu hospedeiro, podendo surgir de três meses até vários anos após a infecção e são, por vezes, inespecíficas. O diagnóstico laboratorial da leishmaniose visceral canina baseia-se na tríade de métodos sorológicos, parasitológicos e moleculares e é essencial para o estadiamento da doença e escolha do tratamento adequado. O tratamento possui como principais objetivos reduzir a carga parasitária do cão, neutralizando a sua capacidade infectante, restaurando adequadamente a sua resposta imune, promovendo a melhora clínica e prevenindo recaídas. O objetivo com esse trabalho foi apresentar uma revisão de literatura expositiva acerca dos aspectos epidemiológicos, diagnóstico, controle e manejo da leishmaniose visceral canina e apresentar relatos de casos de animais diagnosticados positivos atendidos em clínica veterinária particular em Belo Horizonte, Minas Gerais, do ponto de vista clínico e parasitológico, que apresentaram recidivas ao tratamento com a droga leishmanicida miltefosina. O acompanhamento dos casos clínicos apresentados possibilitou uma análise do emprego, aplicabilidade e eficiência dos métodos diagnósticos disponíveis para leishmaniose, e dos tratamentos atualmente disponíveis, sendo útil na orientação do médico veterinário na rotina clínica.
CANINE PANCREATITIS: THE DEVELOPMENT OF THE PANCREATIC INFLAMMATORY CONDITION AND THE CLINICAL-THERAPEUTIC APPROACH
Authors: Gaia de Sousa Felipe , Ribeiro Mendes Ana Cristina
Published: October 2021

Pancreatitis, acute or chronic, is a serious disease for dogs, due to its harmful potential and the existence of underdiagnosis. The disease is still the target of studies regarding its pathophysiology and therapeutic mechanisms, because the signs presented by the animals are nonspecific, ranging from mild to severe presentations. It can cause morphofunctional changes in the pancreas and adjacent organs. The diagnosis can be a very difficult task, either due to the variable symptoms and severity of the disease, or the impasses experienced at the time of the complementary exams. Therapeutic management is defined based on the symptoms presented by the animals, ranging from fluid infusion for volume replacement, analgesics, antiemetics, antibiotics, special food, among others.
El neoconstitucionalismo o constitucionalismo contemporáneo como teoría jurídica y el nuevo papel de los jueces
Authors: Cotrina Maccha Manuel Jesús
Published: October 2021

El neoconstitucionalismo intenta explicar el surgimiento de los Estados constitucionales de derecho europeos y latinoamericanos. En la teoría jurídica, se destacan los aportes de algunos países cuyas reformas constitucionales o nuevas cartas magnas integraron los derechos fundamentales y un alto contenido moral. Respecto a ello, resaltamos la importancia del rol racional, garantista y progresista que los jueces deben desempeñar de acuerdo con los principios y los valores que componen el neoconstitucionalismo.
Interactive Virtual Reality For Fun Mathematics Learning With Deep Understanding At SMP Swasta Ar-Rahman Percut
Authors: Mawengkang Herman , Efendi Syahril , Firdaus Muliawan
Published: October 2021

This partnership program was intended to solve problems that arose at SMP Swasta Ar-Rahman Percut such as the lack of teacher skills in developing learning media to foster students’ motivation and implementing online teaching that optimizes the use of technology. In the context of online learning, such difficulties will increase. The solutions offered were training through workshops on the development of interactive virtual reality (VR) using OpenSpace3D and assistance in the implementation. Five stages: Learn, Teach, Evaluate, Acknowledge, and Fostering in the method were held sequentially. Adult learning principles, focusing on experiential learning and self-motivation, were applied to encourage participants and instructors to actively participate. Results showed that the program has made a significant impact on teachers' skills in developing and implementing interactive VR in fun mathematics online learning.
Effects of Binary Vectors Similarities on the Accuracy of Multi-Criteria Collaborative Filtering
Authors: Demirelli Okkalıoğlu Burcu
Published: October 2021

Recommender systems offer tailored recommendations by employing various algorithms, and collaborative filtering is one of the well-known and commonly used of those. A traditional collaborative filtering system allows users to rate on a single criterion. However, a single criterion may be insufficient to indicate preferences in domains such as restaurants, movies, or tourism. Multi-criteria collaborative filtering provides a multi-dimensional rating option. In similarity-based multi-criteria collaborative filtering schemes, existing similarity methods utilize co-users or co-items regardless of how many there are. However, a high correlation with a few co-ratings does not always provide a reliable neighborhood. Therefore, it is very common, in both single- and multi-criteria collaborative filtering, to weight similarities with functions utilizing the number of co-ratings. Since multi-criteria collaborative filtering is yet growing, it lacks a comprehensive view of the effects of similarity weighting. This work studies multi-criteria collaborative filtering and the literature of binary vector similarities, which are frequently used for weighting, by giving a related taxonomy and conducts extensive experiments to analyze the effects of weighting similarities on item- and user-based multi-criteria collaborative filtering. Experimental findings suggest that prediction accuracy of item-based multi-criteria collaborative filtering can be boosted by especially binary vector similarity measures which do not consider mutual absences.
The Current-Voltage Characteristics for Electrode Geometry Model of Positive DC Corona Discharge in Air
Authors: WARDAYA Asep Yoyo , MUHLİSİN Zaenul , SUSENO Jatmiko Endro , NUR Muhammad , TRİADYAKSA Pandji , KHUMAENİ Ali , SARWOKO Eko , WİNDARTA Jaka , HADİ Susilo
Published: October 2021

Research on corona plasma discharges from plasma reactors has been carried out using the Point and Semicircular-Plane (PSC-P) electrode configuration in the air. The purpose of this study is to compare the suitability level of the current-voltage (I-V) characteristics curve from the results of experimental data and numerical simulation calculations of the electrode geometry function based on the variation of three electrode configuration sizes (small plate, medium plate, and large plate) and two variations of the distance between the two electrodes in each electrode configuration size. The results of the study prove that there is a high degree of conformity between numerical calculations with experimental data through calculations from the Python GUI Programming by taking a fitting value from the certain k-shape sharpness factor. The calculation location of the k-shape sharpness factor lies on the electrode tip sharp surface which will produce the largest plasma flow in the plasma reactor equipment.
Early Estimation of Sewerage Line Costs with Regression Analysis
Authors: SUERİ Murat , ERDAL Mürsel
Published: October 2021

In Turkey, an average of 450 sewer line tenders are made annually and the total line length of these works is approximately 11000000 m. It is very important for both the investor and the contractor to know the costs of the sewer networks with such a large business volume. In this study, models are developed for early estimation of sewage line costs by the regression analysis method. Data belonging to 182 sewer line projects were used in the development of the models. Data on pipe diameter, line length, excavation depth, manhole amount, excavation amount, filling amount, filling type, shoring type, excavation class and real cost parameters were determined through the projects. Correlations between the determined parameters were specified and the parameters suitable for regression analysis were selected. As a result; among the developed estimation models, the equation using all selected parameters with a correlation coefficient of R² = 0.911 gave the most successful result.
Enacting Copywriting Skills during Distance Internship: A Case Study at IQR Foundation
Authors: Purnamasari Yessy , Puji Nur Uzlifah Tri
Published: October 2021

Distance internship rises as global pandemic Covid-19 starts in the beginning of 2020. It forces the higher education institution to re-manage the rules of internship for second year students. As part of the regulation, the internship for Polban students was suggested to be done through distance methods. One of the NGOs that provide distance internships for English Department students is IQR Foundation. This study then investigates the enactment of students' copywriting skills and the challenges during distance internship. The data were collected by combining observation and study literature. The results show this distance internship enables students to apply copywriting skills through three enactments: composing script, creating English subtitles, and collaborating in news writing. Compared to the conventional one, distance internship leads to three main challenges: deciding concepts, using English as the language of communication, and handling the timeline. Distance internship, in many ways, has created many chances for students to grow up and to implement their knowledge in a new paradigm despite the pandemic as the boundary.
Alternatif Perumusan Kebijakan Pemulihan Ekonomi Nasional dalam Masa Pandemi Covid19
Authors: Nurron Ona Martha
Published: October 2021

The purpose of this research is to explore the process of national economic recovery policy formulation, how it was regulated, and searching the alternatives to overcome economic problems along with its benefit and value for businesses and the general public amidst the covid19 pandemic. The qualitative descriptive method is utilized based on the systematic literature review of secondary data. Policy alternatives are determined by comparing policies in two countries, Indonesia and the United States of America. By observing the impact and cause beyond the scope, policy alternatives could be more easily identified, selected, and implemented according to their political feasibility. In accordance with identifying policy alternatives model which divide into two categories, Indonesia’s government employed temporary research analysis while United States federal governments were applying status quo analysis.
O conceito de número na Educação Matemática: uma incursão em pesquisas com crianças
Authors: Botelho Lutieli Rodrigues , Moraes João Carlos Pereira de
Published: October 2021

Essa pesquisa objetiva analisar como o debate sobre o conceito de número tem sido abordado em pesquisas com crianças de Educação Infantil e anos iniciais do Ensino Fundamental, a partir de seus objetivos, metodologias de pesquisa, ensino e inferências. Nesse sentido, produzimos um levantamento em três bancos de dados: BDTD, CTD e ENEM, o que suscitou quinze estudos. A análise dos dados foi feita a partir da metodologia de Análise de Conteúdo (BARDIN, 2011). A partir da análise, levantamos que as pesquisas concentram-se na região Sudeste, em sua maioria são dissertações e há um indício de crescimento dos estudos nos últimos cinco anos. Além disso, quanto aos objetivos de pesquisa, notamos que mesmo as pesquisas envolverem sujeitos crianças, há influência de discussões no campo de ensino. No que se refere às metodologias de ensino e pesquisa, o uso de sequência de atividades e o estudo de caso tem a sua maior evidência. Já no que tange as inferências, notamos que muitas ainda são genéricas e com poucas considerações sobre o conceito de número.
Soil Determination using PH Nutrient Relatively
Authors:   Department of Electronics & Telecommunication Yeshwantrao Chavan College of Engineering Nagpur, India, Masram Bharati , Mehta Harsh ,   Department of Electronics & Telecommunication Yeshwantrao Chavan College of Engineering Nagpur, India, Bokade Harshal ,   Department of Electronics & Telecommunication Yeshwantrao Chavan College of Engineering Nagpur, India, Jain Hritik ,   Department of Electronics & Telecommunication Yeshwantrao Chavan College of Engineering Nagpur, India, Wankhede Shrawani ,   Department of Electronics & Telecommunication Yeshwantrao Chavan College of Engineering Nagpur, India
Published: October 2021

INDIA, an agriculture-based country where the economy is dependent on agriculture and climatic conditions. Primary reason of this project is to fulfil the needs of farming quality by reducing excessive fertilizer abuse by controlling some parameters. So, the parameters are temperature, moisture, light, Ph through which we can identify the suitable crop and its nutrition level. Our project uses 3 types of sensors to increase productivity of the crops. Soil testing for productivity is taken by proposal of supplements needs. We are using Arduino UNO with the sensors. Determining the pH of soil is one of the key parameters for improving crop quality so the amount of the amount of fertilizer used is adequate and not excessive for the crops. Other main sensors used are light and hygrometer sensors. We can classify plants based on their light needs like high, medium or low. So, the light received by the crops depends upon the nearness of light. We should adequately address spatial variation for crop productivity when we consider pH to rejuvenate agriculture.
A Deep Convolutional Neural Network Architecture for Cancer Diagnosis using Histopathological Images
Authors:   Department of Computer Science and Engineering, GITAM Institute of Technology, GITAM Deemed to be University, Visakhapatnam, India., Gidijala Karthika , Pappu Mansa Devi ,   Department of Computer Science and Engineering, GITAM Institute of Technology, GITAM Deemed to be University, Visakhapatnam, India., Vavilapalli Manasa ,   Department of Computer Science and Engineering, Dadi Institute of Engineering and Technology, Visakhapatnam, India., Kothuru Mahesh ,   Department of Computer Science and Engineering, GITAM Institute of Technology, GITAM Deemed University, Visakhapatnam, India.
Published: October 2021

Many different models of Convolution Neural Networks exist in the Deep Learning studies. The application and prudence of the algorithms is known only when they are implemented with strong datasets. The histopathological images of breast cancer are considered as to have much number of haphazard structures and textures. Dealing with such images is a challenging issue in deep learning. Working on wet labs and in coherence to the results many research have blogged with novel annotations in the research. In this paper, we are presenting a model that can work efficiently on the raw images with different resolutions and alleviating with the problems of the presence of the structures and textures. The proposed model achieves considerably good results useful for decision making in cancer diagnosis.