bluuebunny/crossref_metadata_2025 huggingface dataset:
Artificial neural network analysis of Prefrontal fNIRS Blood Oxygenation Recordings
Authors: Ehleben Wilhelm , Horschig Jörn M. , Acker Helmut
Published: August 2023

Noninvasive functional near infra-red spectroscopy (fNIRS) measuring brain oxygenated (O2Hb) and deoxygenated hemoglobin (HHb) is a promising technique for studying dementia diseases. fNIRS signals are determined by cerebral and extracerebral factors as for instance neuronal activity, degree of neurovascular coupling (NVC), blood flow dependency on heart rate (HR), ventilation controlling blood oxygenation (SaO2) or autonomic nerve activity (ANA). These factors regulate different body functions such as vascular resistance in coordination with the brain. The simultaneous measurement of as many as possible anatomical and physiological factors during fNIRS of the brain is a prerequisite to interpret fNIRS signals with respect to the degree of brain tissue oxygenation. We measured brain O2Hb-HHb relation by fNIRS and four bipolar EEG recordings simultaneously with HR, blood volume changes, SaO2 and galvanic skin resistance as ANA marker. We analyzed the EEG recordings by a Fourier power analysis (delta, theta, alpha, beta, gamma frequencies). All modalities together resulted finally in 24 parameters. We investigated their probable influence on the fNIRS brain O2Hb-HHb signal. The importance of each parameter for the fNIRS signal was assessed by nonlinear regression using an artificial neural network (ANN) analysis as a new tool of fNIRS signal interpretation. We applied fNIRS to 5 healthy control patients and to 5 patients with brain disorders (BD) known to have a disturbed NVC as for instance described for Alzheimer disease. The fNIRS recordings of brain O2Hb and HHb of control patients responding to different task challenges like breath holding, odor presentation, skin touching or listening to music is mainly influenced by SaO2 and HR changes masking NVC signals due to low EEG power frequency activities as assessed by ANN. The fNIRS recordings of brain O2Hb and HHb changes of BD patients responding to the different task challenges, however, is mainly influenced by high gamma and low theta EEG power frequencies as expression of high NVC activity. Brain O2Hb-HHb relation in response to different task challenges is significantly reduced in BD patients hinting to a disturbed brain blood microcirculation. These strategies might be useful to follow up the therapeutic success cognition deficiencies in general medicine ambulance.
The association between the number of teeth and frailty among older adults: a systematic review and meta-analysis
Authors: Zhang Xiao-Ming , Cao Simin , Teng Liting , Xie Xiaohua , Wu Xinjuan
Published: August 2023

Background
As people age, tooth loss often accompanies the process of aging in the elderly. There were several studies to explore the association between the number of teeth and frailty among older people, with inconsistent results. We aimed to summarize the evidence for the association between tooth loss and frailty among older adults by using systematic review.
Methods
We systematically searched PubMed, Embase, and Ovid databases. Observational studies were included to examine the relationship between tooth loss and frailty in older adults. The Newcastle‒Ottawa scale was used to evaluate the studies’ quality.
Results
A total of 1454 articles were identified from the retrieved databases. We extracted 17 studies involving 24,897 participants for the final analysis. The pooled association between the number of teeth and frailty among older adults was 0.98 (Odd ratio, OR) (95% confidence interval [CI]: 0.97 − 0.99). In addition, older people with fewer than 20 teeth had a higher risk of frailty than those with more than 20 teeth, the pooled OR was 1.91 (95% CI: 1.48 − 2.47). Tooth loss increases the risk of frailty, regardless of age group, study design, setting, and frailty assessment tools (P<0.05).
Conclusions
Our study revealed a negative association between the number of teeth and frailty among older individuals. Furthermore, older people with fewer than 20 teeth faced a higher risk of frailty compared to those with more than 20 teeth.
Longitudinal analysis of quality of life in primary lung cancer patients with chlamydia pneumoniae infection: a time-to-deterioration model
Authors: Chen Zishan , Zhuang Jinman , Liu Maolin , Xu Xinying , Liu Yuhang , Yang Shuyan , Xie Jinbao , Lin Nanlong , Lai Fancai , He Fei
Published: August 2023

Purpose
Chlamydia pneumoniae (Cpn) infection has been strongly associated with lung cancer, but its impact on patients' Health-Related Quality of Life (HRQoL) remains unclear. Our objective was to investigate the relationship between pre-treatment Cpn infection and time to deterioration (TTD) of HRQoL in patients with primary lung cancer.
Methods
We conducted a hospital-based prospective study. Cpn infection was detected by microimmunofluorescence method. HRQoL was assessed at baseline and during follow-up using the EORTC Quality of Life Questionnaire version 3.0 (EORTC QLQ-C30) and EORTC Quality of Life Questionnaire-Lung Cancer (EORTC QLQ-LC13). HRQoL scores were calculated using the QoLR package, and TTD events were determined (minimum clinically significant difference = 5 points). Cox regression analysis was used to evaluate the effect of Cpn infection on HRQoL.
Results
For EORTC QLQ-C30, Physical function (PF) and Pain (PA) TTD events on the functional scale and Symptom scale were the most common during follow-up. After adjusting for gender and smoking status, Pre-treatment Cpn IgA + was found to signifcantly delay TTD of Physical functioning (HR = 0.539, 95% CI: 0.291–0.996, P = 0.048). In addition, Cpn IgG + before treatment significantly delayed TTD in Emotional functioning (HR = 0.310, 95% CI: 0.115–0.836, P = 0.021). For EORTC QLQ-LC13, deterioration of dyspnea (LC-DY) was the most common event. However, Cpn infection before treatment had no effect on the TTD of EORTC QLQ-LC13 items.
Conclusions
In EORTC QLQ-C30 and EORTC QLQ-LC13, Cpn IgA delayed TTD in Physical functioning and Cpn IgG delayed TTD in Emotional functioning.
Identification an novel classification and nomogram of programmed cell-death patterns for investigating the immune microenvironment and prognosis of postoperative ovarian cancer patients
Authors: Han Lei , Wang Fei , Chen Weiwei , Zhai Qingliang , Zhang Xianghui , Xu Huishu , Zhang Baolin , Wang Yanlin , An Jiajia , Pan Yitong
Published: August 2023

Background: Ovarian cancer (OV) is a highly aggressive and often fatal disease that frequently goes undetected until it has already metastasized. The classic treatment for ovarian cancer involves surgery followed by chemotherapy. However, despite the effectiveness of surgery, relapse is still a common occurrence. Unfortunately, there is currently no ideal predictive model for the progression and drug sensitivity of postoperative ovarian cancer patients. Cell death patterns play an important role in tumor progression and have the potential to be used as indicators of postoperative OV prognosis and drug sensitivity.
Materials and methods: A total of 12 PCD patterns were employed to construct novel classification and prognosis model. Bulk transcriptome, single-cell transcriptome, genomics, and clinical information were collected from TCGA-OV, GSE9891, GSE26712, GSE49997 and GSE63885. In addition, single-cell transcriptome data GSE210347 was procured from the Gene Expression Omnibus (GEO) database for subsequent analysis.
Results: In this study, a novel PCD classification has been employed to phenotype postoperative ovarian cancer patients, revealing that patients in cluster 1 exhibit heightened sensitivity to immune-based therapies. Meanwhile, a programmed cell death index (PCDI) was established using an 8-gene signature with the help of a machine learning algorithm. The PCDI was validated in four independent datasets, and it was found that patients with high-PCDI had a worse prognosis after surgery in OV. The investigation also revealed that PCDI is associated with chemokines, interleukins, interferons, and checkpoint genes, as well as important components of the immune microenvironment, as determined through a comprehensive analysis of bulk and single-cell transcriptomes. In addition, we also found that patients with low-PCDI values may exhibit sensitivity to immunotherapy, while those with high PCDI values may display increased responsiveness to tyrosine kinase inhibitors.
Conclusion: This study provides new insights into the significance of programmed cell death (PCD) patterns in ovarian cancer patients following surgery. Through a comprehensive analysis of different cell death patterns, we have developed a novel PCD model and nomogram that can effectively predict the clinical prognosis and drug sensitivity of OV patients post-surgery.
Research Misconduct in Moroccan Medical Professionals: Insights from a Cross-Sectional Study on Attitudes and Experiences
Authors: Moujtahid Hajar , Bairi Khalid El , Ammar Nadir , Mbarki Aamer , Belayachi Jihane , Razine Rachid , Abouqal Redouane , Hmamouchi Ihsane
Published: August 2023

Objective:
To explore the experiences and attitudes of Moroccan medical students towards research integrity and scientific misconduct.
Methods:
A cross-sectional web survey, incorporating the Research Misbehavior severity score (RMSS-Q) and Kalichman attitudes surveys, was distributed to doctors and medical students in five Moroccan medical universities. The survey, disseminated via email and social media platforms, included close-ended questions to assess attitudes towards research misconduct and gather participants' self-reported experiences with such unethical practices. Univariate and multivariable logistic regression analyses were used to evaluate the predictors of misconduct.
Results:
A total of 1500 medical students and residents were targeted. 335 of them responded, making a response rate of 22,4%. 57.3% were women and the mean age was 24.5 ±2.18.43.3% of the students were in 5th year whereas 51.6% were in the 6th year of Medical School. Among the participants, only 36.1% reported previous research experience.
Regarding acts of misconduct, 85.62% and 86.7% of respondents expressed agreement with items related to falsification and plagiarism, respectively, as indicated by the Kalichman questionnaire. 63.6% of respondents admitted to engaging in scientific misconduct at least once. No significant associations were found between age, sex, academic level, or research experience and the likelihood of committing misconduct in the multivariable analysis.
Conclusion:
In conclusion, our study underscores the concern of research misconduct among medical students while revealing a considerable gap in comprehending the core factors driving such unethical behavior. This underscores the importance of investigating the effectiveness of targeted training approaches and interventions. By nurturing an environment that promotes research integrity and ethical conduct within the sphere of medical education, we can pave the way for a more conscientious and principled research community.
Transit Pass Ownership as a Potential Source of Heterogeneity in the Determinants of Ride-sourcing Use in Metro Vancouver
Authors: Mash Sk Md , Loa Patrick , Ong Felita , Habib Khandker Nurul
Published: August 2023

Amid the increased utilization of ride-sourcing, the relationship between these services and public transit received significant attention from policymakers and researchers. Prior studies have found that ride-sourcing has mixed impacts on transit ridership and that transit use tends to be positively associated with ride-sourcing use. However, these studies have primarily treated transit use and transit pass ownership as explanatory variables. Given the potential for ride-sourcing to influence transit use, further work is needed to understand the relationship between these services. To explore whether transit pass ownership is a source of heterogeneity among ride-sourcing users, this study uses an econometric model to explore the impacts of transit pass ownership on the determinants of ride-sourcing use in Metro Vancouver. Using data from a web-based survey, a two-stage model is used to jointly model transit pass ownership, ride-sourcing adoption, and ride-sourcing frequency. The results demonstrate the potential for transit pass ownership to be a source of heterogeneity among ride-sourcing users. Specifically, the factors influencing ride-sourcing use (and the elasticity of these factors) were found to differ based on transit pass ownership. Additionally, the results suggest that attitudes and perceptions toward ride-sourcing can influence transit pass ownership. These findings can help inform targeted approaches to limiting the negative impacts of ride-sourcing on transit use.
Silencing GDI2 inhibits proliferation, migration and invasion of colorectal cancer through activation of p53 signaling pathway
Authors: Ou Wen-Ting , Tan Rong-Jian , Sun Li-Jun , Xu Fei-Peng , Huang Xian-Jin , Quan Zhen-Hao , Zhou Cai-Jin
Published: August 2023

Objective
To investigate the effect of silencing GDP dissociation inhibitor 2 (GDI2) on colorectal cancer development and possible mechanisms based on transcriptomic analysis.
Methods
The differences in the expression levels of GDI2 in normal colorectal tissues and tumor tissues of colorectal cancer (CRC) patients were detected. The correlation of GDI2 expression levels with survival and clinical characteristics of CRC patients was analyzed. The effects of GDI2 expression levels on the biological functions of CRC cells were examined by CCK-8 assay, plate clone formation assay, wound healing assay and Transwell assay. The effect of GDI2 on the proliferation and growth of xenograft tumors was investigated by a xenograft tumor model of CRC in nude mice. Based on transcriptomics, we explored the possible mechanisms and related pathways of the effect of silencing GDI2 on CRC cells. A series of cellular experiments and western blot assays were performed to verify the possible mechanisms and related-pathway of GDI2 action on CRC.
Results
The expression levels of GDI2 in CRC tissues and cells were higher than those in normal tissues and cells. The expression level of GDI2 correlated with clinical characteristics such as lymphatic metastasis, tumor stage, tumor volume and lymphocyte count. Silencing of GDI2 reduced the proliferative activity and migration and invasion ability of CRC cells, as well as inhibited the proliferation of CRC xenograft tumors. The differentially expressed genes were significantly enriched in biological processes such as cell cycle arrest and p53 signaling pathway after GDI2 silencing. The percentage of G0/G1 phase cells in CRC cells was increased after silencing GDI2 as verified by flow cytometry. RAB5A was highly associated with the p53 pathway and could interact with TP53 via ZFYVE20 protein. The mutual binding between GDI2 protein and RAB5A protein was verified by immunoprecipitation assay. Silencing GDI2 while overexpressing RAB5A reversed the reduced proliferation, migration and invasion ability as well as cell cycle arrest of CRC cells. Meanwhile, the addition of p53 signaling pathway inhibitor (PFT-α) also reversed the biological effects of silencing GDI2 on CRC cells. The p-p21 and p-p53 protein expression levels were significantly greater in the sh-GDI2 group than in the sh-NC group. However, the p-p21 and p-p53 protein expression levels were reduced after silencing GDI2 while overexpressing RAB5A.
Conclusion
Silencing GDI2 activates the p53 signaling pathway by regulating RAB5A expression levels, which in turn induces cell cycle arrest and ultimately affects the proliferative activity, migration and invasive ability of CRC cells.
Identification of Immunogenic cell death-Related Subgroups and Prognosis Model in lung adenocarcinoma
Authors: Ma Jing , Ren Juan , Chen Hong
Published: August 2023

Purpose: Immunogenic cell death (ICD), as a form of regulatory cell death (RCD), influences the occurrence and development of tumors by activating adaptive immune response and altering tumor microenvironment. This research aimed to determine the function of ICD in lung adenocarcinoma and constructed an ICD-related prognostic model.
Methods: Download gene expression and clinical data from the TCGA Cancer Genome Atlas. Two ICD-related subtypes were identified by consensus clustering. Patients with lung adenocarcinoma (LUAD) in the TCGA database were then randomly divided into a training set and a test set in a 1:1 ratio. In the training set, Lasso Cox regression and multivariate Cox regression were used to construct a prognostic risk model, and patients were divided into high-risk and low-risk groups, which were validated in the test set. In addition, we established a prognostic Nomogram based on the TCGA-LUAD dataset.
Results: Based on univariate Cox analysis, 28 ICD related genes were screened for consensus clustering analysis, and two ICD subgroups were established. The high expression subgroup of ICD was associated with poor prognosis and abundant immune cell infiltration. In addition, seven prognostic gene features were constructed to predict the OS of LUAD patients, and there was a certain correlation between immune cells and risk scores.
Conclusion: In conclusion, we found ICD-related subtypes and prognostic genes in LUAD, which may have some guiding significance for the survival and treatment of lung adenocarcinoma patients.
Innovative Combined Technology With Encapsulated Evoo and Infrared Processing Against Salmonella and Listeria Monocytogenes in Breaded Poultry Products
Authors: Barón-Yusty Marta , Martínez-Hernández Ginés Benito , Ros-Chumillas María , López-Gómez Antonio
Published: August 2023

The high Salmonella and Listeria monocytogenes risk in poultry products reinforces the urgent need for new technologies with high antimicrobial effects. In that sense, a combined technology consisting of encapsulated Extra Virgin Olive Oil (EVOO) during chicken nugget breading combined with infrared processing was hereby studied at three levels (experiments). The high in vitro EVOO antimicrobial activity (up to 74 %), which was 1.2-fold higher against L. monocytogenesthan Salmonella, was enhanced after encapsulation (α-cyclodextrin) by 1.5-2.0 and 1.2-1.6-fold, respectively (Experiment 1). Oil-free processing (infrared and convection ovens) combined with encapsulated EVOO (2.5 and 1.6 % EVOO doses) even enhanced the high in vitro antimicrobial activity of encapsulated EVOO (Experiment 2). In the in vivo study (Experiment 3), infrared (180 ºC, 6.4 min)+convection air (120 ºC, 10 min) processing combined with encapsulated EVOO (1.6 and 2.5 %) within chicken nugget breading of the chicken nuggets achieved in vivo antimicrobial reductions of 60 and 80 % against Salmonella and L. monocytogenes, respectively. In conclusion, this new technology including encapsulated EVOO (1.6-2.5 %) within the breading of chicken nuggets and innovative oil-free processing may ensure the food safety of these poultry products very susceptible to the incidence of Salmonella and L. monocytogenes.
Direct and indirect effects of energy intensity on environmental quality in West Africa
Authors: Kouakou Auguste K. , Soro Nibontenin
Published: August 2023

This paper aims to analyze the environmental effect of energy intensity and its role in determining the impact of industrial production and transport services on environmental quality in West African countries. Based on co-integration relationships and exogeneity tests, we estimate a vector error correction model with exogenous variables for 14 countries. The results show that economic growth, industrial production, and higher energy intensity increase greenhouse gas emissions in the long term. Thus, improving energy efficiency through a reduction in its intensity should generate a positive environmental impact. Furthermore, increasing energy intensity amplifies the adverse environmental effects of industrialization, confirming a positive relationship between industrialization and environmental quality. The sectoral impact of energy efficiency strategies should therefore be questioned. These findings imply that policymakers in West African countries should implement environmental awareness programs and policies that increase energy efficiency by supporting energy-saving technologies and promoting an eco-friendly transportation policy.
Fragment library screening by X-ray crystallography and hit optimization against thioredoxin glutathione reductase of Schistosoma mansoni
Authors: Neto Lauro Ribeiro Souza , Montoya Bogar Omar , Moreira-Filho José Teófilo , Brandão-Neto José , Verma Anil , Bowyer Sebastian , Dantas Rafael Ferreira , Neves Bruno Junior , Delft Frank , Owens Raymond J. , Furnham Nicholas , Andrade Carolina Horta , Silva Floriano Paes
Published: August 2023

Schistosomiasis is caused by parasites of the genus Schistosoma, which infect more than 200 million people. While praziquantel (PZQ) has been the main drug for controlling schistosomiasis for over four decades, PZQ drug resistant strains have already been reported, highlighting the need to search for new schistosomicidal drugs. S. mansoni survival relies on the redox enzyme thioredoxin glutathione reductase (SmTGR), a validated target for the development of new anti-schistosomal drugs. Here we report a fragment screening campaign of 768 compounds against SmTGR using X-ray crystallography and our efforts to optimize the hits found into potent inhibitors. We observed 49 binding events involving 35 distinct molecular fragments which were found to be distributed across 16 binding sites. Most sites are described for the first time within SmTGR, a noteworthy exception being the “door stop pocket” near the NADPH binding site. Fragments binding to the latter were prioritized to undergo a “SAR by catalog” strategy for optimization into potential inhibitors. A search for compounds containing any of the prioritized fragments as a substructure was made in commercial databases. The ability of these compounds to inhibit SmTGR was predicted based on a binary ML classification model, followed by an analysis of the putative binding mode by molecular docking. The 38 best ranked compounds were purchased and experimentally evaluated for SmTGR inhibition. Compound 14 inhibited 63.6% of enzyme activity at 100 µM and presented an estimated IC50 of 33 µM against SmTGR.
Visual Memory and Spatial Navigation as Preclinical Indicators of Alzheimer's Disease
Authors: Nevers Jennifer
Published: August 2023

INTRODUCTION: There is an absence of standardized measures for spatial navigation (SN) deficits related to possible visual memory (VM) decline in preclinical Alzheimer’s disease (AD). This work sought to identify VM changes over time in the cognitively normal (CN) years of those later diagnosed with AD (pre-AD) compared to those who remained CN (non-AD).
METHODS: Mixed-effects analysis was performed on the Benson Complex Figure Test (BCTF) delayed recall scores for VM on longitudinal (1-6 years) of pre-AD and non-AD samples from the National Alzheimer’s Coordinating Center. Analysis for sex differences was included.
RESULTS: All pre-AD groups demonstrated a significant (P < .001) decrease in VM over time compared to non-AD groups with a Cohen’s d range of .853 to 1.076 across time points.
DISCUSSION: The BCTF may serve as an AD screening instrument in CN persons and support inquiry to identify potential SN deficits secondary to VM decline.
Determinantes do projeto de integração regional da Europa o Eixo Franco-germânico e o Papel dos Estados Unidos
Authors: Nasser de Carvalho Patrícia
Published: August 2023

O objetivo deste trabalho é analisar o papel de dois determinantes do projeto de integração regional da Europa após o final da Segunda Guerra Mundial: as relações entre França e Alemanha, as maiores economias europeias, e onde se concentravam as maiores rivalidades históricas continentais; e o apoio dos Estados Unidos à reconstrução e ao projeto de europeu de integração regional no contexto geopolítico da Guerra Fria. Depois de algumas propostas anteriores e diante dessas frágeis circunstâncias econômicas, políticas e sociais e da ameaça comunista, foram retomadas antigas “ideias de Europa”, isto é, a situação pós-conflito induziu o retorno de diferentes percepções sobre a necessidade de se buscar a paz por meio da união dos povos europeus. Seu resultado foi a formação da primeira Comunidade Europeia no início da década de 1950, e quatro décadas depois, a fundação da União Europeia (UE).
PROBLEMATIZAÇÕES SOBRE ACESSO E PERMANÊNCIA DE ESTUDANTES LGBTQIA+ NA UNIVERSIDADE PÚBLICA: APONTAMENTOS SOBRE PRODUÇÕES ACADÊMICAS
Authors: Prado Vagner Matias do , Altmann Helena
Published: August 2023

O trabalho analisou produções acadêmicas da área da Educação sobre acesso e permanência de estudantes LGBTQIA+ no ensino superior. Utilizou-se o levantamento sistemático de artigos nas bases Lilacs e SciELO. Dos nove trabalhos encontrados, apenas duas investigações tiveram como protagonistas estudantes LGBTQIA+. Os resultados apontam para possibilidades investigativas, visto que o tema parece se configurar como uma “nova questão” para a área da Educação. Sinalizam para discussões profícuas que poderiam contribuir para ampliar debates sobre cotas.
SITUAÇÃO JUVENIL NO CONTEXTO DA EDUCAÇÃO EM TEMPOS DE PANDEMIA
Authors: Silva Tarcisio Augusto Alves da , Pereira Lucas Péricles de França , Sarinho Bárbara Santos
Published: August 2023

O ato de estudar durante a pandemia mostrou maiores e menores contrastes, a depender da classe social, do gênero, da cor e da localidade onde o jovem reside. Neste trabalho, procuramos apresentar os resultados de uma investigação com estudantes de Ensino médio. Do ponto de vista metodológico, aplicamos um questionário misto, on-line, a uma amostra não probabilística de 394 jovens, além da realização de 09 entrevistas semiestruturadas. Os resultados traduzem a realidade do ensino remoto e os desafios, e estratégias estabelecidas para estudar durante a pandemia.
UM ESTUDO SOBRE A DECLARAÇÃO DE MISSÃO DAS UNIVERSIDADES FEDERAIS BRASILEIRAS
Authors: Simões Lincon , Ciasca Maria Isabel
Published: August 2023

O presente artigo investigou o léxico das declarações de missão de 62 universidades federais, por meio da ferramenta Voyant Tools, a fim de identificar os termos mais frequentes, suas coocorrências e o contexto de aplicação. Os resultados revelaram a presença de três temas recorrentes: o conhecimento, a formação de pessoas e o desenvolvimento da sociedade. Contrariamente a estudos realizados em outros países, constatou-se que as declarações possuem poucos elementos de distinção entre si, com exceção para a região de atuação, o que pode refletir formatos organizacionais semelhantes.
A PRESENÇA DE PAULO FREIRE NOS PROGRAMAS DE PÓS-GRADUAÇÃO STRICTO SENSU EM EDUCAÇÃO DE UNIVERSIDADES COMUNITÁRIAS DO SUL DO BRASIL
Authors: Tessaro Mônica , Dos Santos Paulo Fernanda
Published: August 2023

Objetiva-se identificar e analisar o tipo de presença de Paulo Freire nas pesquisas defendidas nos Programas de Pós-Graduação Stricto Sensu na área da Educação, das Universidades Comunitárias que integram o sistema da Associação Catarinense das Fundações Educacionais. Trata-se de um estudo qualitativo bibliográfico, cuja amostra é representada por 119 trabalhos vinculados a 10 universidades comunitárias. Para análise dos dados, utilizou-se da pedagogia crítica com base na hermenêutica-dialética. A presença de freiriana é representada por dois tipos: teórico-metodológica e teórico-conceitual.
Women's Multiple Roles and Social Pressure in Agrarian Society
Authors: Mutolib Abdul , Nuraini Candra
Published: August 2023

Since 1960, the transmigration program between Java Island and Lampung Province has been massive. Some of the transmigration players are impoverished farmers seeking fresh farmland. The financial conditions of transmigrants motivate women to work in both the domestic and productive sectors. This study aims to determine women's roles and the effect of social pressure on women's roles in the agricultural region of the transmigration area in Pringsewu Regency, Lampung Province. The study was performed between November 2021 and March 2022. The research employed a qualitative case study approach. Forty respondents serve as both housewives and productive agricultural workers. The results of the study indicate that women in the Pringsewu transmigration area have three roles: housewife (domestic work), productive work (farming), and social work. Women play these equivalent roles as men in agricultural work. Women who do not engage in productive work (farming) are considered unproductive among their family and neighbors who make up stories about them. In agrarian societies in transmigration areas, a low level of education encourages the persistence of inequality. To achieve gender equality, numerous stakeholders must collaborate and maintain their efforts, particularly in agricultural communities in transmigration areas.
Exploring Gender Differences in Public Speaking Anxiety
Authors: Rahman Hz Benni Ichsanda
Published: August 2023

Comprehending the factors that lead to public speaking anxiety is crucial; this includes gender distinction. This research was aimed at examining the levels of students' English public speaking anxiety in the context of their gender differences. This study included 63 (21 males and 42 females) English Language Education Study Program students from one of the state universities in North Sumatra. To examine this phenomenon in its natural environment, a mixing technique was used. An examination of records was utilized to collect the required data. The data was then analyzed in two distinct ways: a statistical calculation was performed on the results of 17-question student questionnaires on their level of public speaking anxiety, and a constructive analysis was performed by comparing the responses of various respondents. On average, male participants in this study reported lower levels of anxiety than female ones. The difference between 50.52 and 57.14 is substantial. “I am anxious that I will embarrass myself in front of the audience,” “I am anxious before speaking,” and “I am worried that my audience will think I am a poor speaker” are the areas where female respondents are more anxious than male. It is necessary to do more research with a bigger number and variety of respondents.
Structural Analysis of Steel Truss and Masonry Bridge Interaction: A Case of Ali Fuat Pasha Bridge in Sakarya, Türkiye
Authors: AKŞAR Bora , OZDEMİR Muhammed Alperen , TUTAR Ali İkbal , ÇAKIR Ferit
Published: August 2023

Restoration of historical structures using new materials and techniques is widespread worldwide. In these applications, relatively new materials such as steel, concrete, reinforced concrete (RC), or composite are generally preferred. However, it is often ignored whether old materials and new materials work in compatibility. In this respect, Ali Fuat Pasha Bridge (or Bayezid II Bridge), which was built by Bayezid II in 1495 over the Sakarya River in Geyve-Sakarya, was examined. The bridge is 196.50 meters long and consists of 15 arches with different spans and three arches of the bridge were destroyed as a result of the earthquake. Then, the bridge has been restored by constructing a steel truss system in place of the destroyed arches. Within the scope of this study, the structural performance of the bridge, which is currently serving vehicle and pedestrian traffic, is examined by using finite element analyses (FEAs). Moreover, this research examines the combined behavior of steel and masonry materials and investigates the structural behavior of steel truss and masonry bridge interaction. According to the results of the analyses, there are significant behavioral differences between the masonry structure and the steel structure. The main cause for this disparity is thought to be the varying levels of stiffness and ductility in steel and masonry sections.
Şeker Pancarı Üretiminde Yetiştirici Uygulamaları: Muş İli Örneği
Authors: YAŞAR Mustafa , ŞAHİN Kasım
Published: August 2023

Bu çalışmada amaç, Muş ilinde şeker pancarı yetiştiriciliği yapan işletmelerde işletme yönetimi ve çiftçi uygulamalarına yönelik değerlendirme yapmaktır. Çalışmada, Muş ilinde şeker pancarı üretimi yapan 74 işletme sahibi ile 2019 yılında yüz yüze anket yoluyla elde edilen veriler değerlendirilmiştir. Yapılan değerlendirmede üreticilerin büyük çoğunluğunun 25 dekar ve üzeri arazide üretim yaptıkları, ortalama 6.1 t da-1 ton şeker pancarı elde ettikleri ve elde edilen şeker pancarının yıllık ortalama 17.7 polar oranına sahip olduğu, üretici başına şeker pancarı kota miktarının 388.3 ton olduğu belirlenmiştir. Üreticilerin 10 yıl ve üzeri üretim deneyimine sahip oldukları, %89.2’sinin ürünlerine sigorta yaptırmadıkları, %32.4’ünün kredi kullandıkları ve bir sonraki yıl ekilecek ürün için büyük çoğunluğunun (%58.1) ürün fiyatlarına göre karar verdikleri belirlenmiştir. Üreticilerin %70.3’ünün Nisan, %29.7’sinin Mayıs ayı içinde ekim yaptıkları, %77’nin 6-12 kez arasında sulama yaptıkları, %28.4’ünün söküm öncesi potasyum uygulaması yaptığı ve sökümleri %32.4’ünün Eylül ayı sonrasında, %67.6’sının Ekim ayı ilk haftasını tercih ettikleri belirlenmiştir. Şeker pancarı tarımı şeker hammaddesinin elde edilmesinin yanında melas, şeker pancarı posası, şeker pancarı yaprakları gibi ürünlerin işlenmesiyle silaj yapımı, maya ve alkol üretimi gibi birçok ürüne kaynak oluşturmak ve kırsalda istihdama katkı sağlamaktadır. Türkiye ekonomisine büyük katkıları yanında birçok sanayi koluna hammadde sağlayan şeker pancarı bitkisi üretiminin her yönüyle daha sistematik olarak (siyasi, ekonomik ve tarımsal uygulamalar) sürdürülebilirliği sağlanmalıdır.
The Effect of Sardines Fish Oil Waste Into The Diets on The Chemical Quality of Laying Hen Egg
Authors: Fadlilah Anik , Susanto Edy , Muthoharoh Husnul , Susila Ida , Wahyuni Wahyuni , Sutanto Edi , Handayani Ike Mawarni , Alilmi M. Dzulfikri , Mustofa M. Muhid
Published: August 2023

The Functional eggs could be used as food for stunting sufferers. Functional eggs could be produced by feed modification using sardines fish oil waste (SFOW) into diets. This research determined the effect of sardines fish oil waste on the diets of UD Sumber Rejeki. The material used chicken eggs produced by 60 laying hens aged 12 months. The method used in this study was laboratory analysis with a completely randomized design consisting of 4 treatments and 3 replications. The treatments were mainly fed by adding 0%, 5%, 10%, and 15% SFOW. Laying hens were given treatment for 1 month and then the eggs produced were tested for chemical quality which included levels of protein, fat, water, carbohydrates, total energy, and cholesterol. The research data were analyzed using analysis of variance and continued by testing the average smallest significant difference (BNT). The sardines fish oil waste into the diets did not affect the protein, fat, moisture, and carbohydrate content of laying hen eggs, and significant effect on energy total and cholesterol content of laying hen egg. The chemical quality of laying hen egg consist of a protein content was 12.18-12.47%, fat content was 7.79-8.89%, moisture content was 76.45-77.58%, carbohydrate content was 0.93-1.44%, ash content eggs was 0.88-0.94%, the energy total was 125.75-134.54 Kcal/100 gram, and egg cholesterol content was 267.04-365.68 mg/100g egg. Based on the results of this research, the best addition of waste sardine fish oil was 5% to production costs efficient to produce functional eggs in UD Sumber Rejeki for stunting sufferers, especially in the Lamongan Regency
Technical Analysis as a Tool to Predict Stock Behaviour - A Study of BSE FMCG Stocks
Authors: Gujrati Shishir
Published: August 2023

A stock market is a place that decides the liquidity of security by offering trading facilities. The price behavior of stocks reflects themovements in their respective sector or companies. The technical analysis, as a tool, offers insight into the price movements of thesesecurities and tries to forecast the future price trends by using various tools like RSI, MACD, EMA, etc. These trends can be for short orlong term. The paper attempts to analyze and forecast the price movements of certain FMCG sector companies which are a part of Sensexwith the help of various technical analysis tools. The paper also attempts to take an insight into the power of these tools to predict stockprices under various conditions
Visual Merchandising and Impulsive Purchase Tendency: An Empirical Study of Consumers In Apparel Sector
Authors: Asma  , Afsha Afreen
Published: August 2023

PurposeThis study intends to investigate the impact of four elements of visual merchandising namely window display, mannequin display as wellas floor merchandising and promotional signage on impulse buying behaviour of customers in the apparel sector.MethodologyThe respondents of the given study constitute 200 customers from Varanasi. The responses were collected online via Google forms sincethe offline collection was not suitable due to Covid 19 norms.FindingsThe study revealed that all four elements of visual merchandising exert a significant influence on the impulse buying behaviour ofcustomers in the apparel sector. Promotional signage has the highest impact followed by the window display, floor merchandising, andmannequin display.ValueVisual merchandising influences closely impulse buying. And given the importance of impulse purchase in retailers’ sales revenue, itbecomes relevant to understanding the impact of visual merchandising on impulse buying tendency.
Post Implementation Issues of Goods and Services Tax in India
Authors: Anju Singh  , Kripa Shanker Jaiswal
Published: August 2023

GST was declared as India's second intended attempt. But several months ago, on 1 July 2017, India as a country had made a big leaptowards a new order in its tax history which is undoubted, one of the important and revolutionary indirect fiscal reforms in Indian historysince independence. In addition, the post-GST era has so far seen the exporter numerous blows, errors, and incompatibility in archivedreturns as well as the World Bank calling GST a very complicated tax system. The GST Act prior to its implementation faced theresistance of state governments due to fear of loss of income for state governments. The current GST has certain problems in the system.In addition, there are only two countries apart from India, namely, Canada and Brazil have applied the dual GST model. In most othercountries of the world there is only one single tax system that is VAT or GST.The following study focuses on getting a meaningful idea about The challenges and prospects of post-GST application in India and thedifference between the Indian model of GST and similar taxes in other countries is the double GST Model. This study seeks to clarify theproblems of subsequent application of goods and services tax in India and how experience in GST raises a larger point, and maybe ithighlights a future lesson, about policy reforms. After two years in the time of the pandemic significantly after the closure, it has becomedifficult to manage for businessmen. Meanwhile, the government has been proactive in resolving the problems faced by Indian taxpayers.There are still gaps between the expectation and actual application of GST in terms of a simplified tax structure, ease of doing business,and overall price reduction.This study discusses the main problems of how goods and services tax affects the Indian economy and after the results are applied athorough understanding of GST in some other countries of the world. In addition, these issues have been raised during the postimplementationperiod, as well as critically analysing the expectation and the difference between their reality.
The Multifunctionality of Vestial Vocabulary in the Artistic Portrait of V.A. Gilyarovsky (based on the Autobiographical Novels "My Wanderings" and "People of the Theater")
Authors: Letapurs T. V. , Malykhina T. M.
Published: August 2023

The journalistic legacy of V.A. Gilyarovsky has been studied in sufficient detail, to a lesser extent, the attention of scientists was riveted to his autobiographical prose - the stories "My Wanderings" and "People of the Theater", the author's manner, the expression of an individual vision of the world and man. The article deals with the linguistic and stylistic features of the portrait of V.A. Gilyarovsky and reveals the originality of the vestial vocabulary, its function in describing the appearance of heroes of different social strata.

The purpose of the study is to study the themes and problems of autobiographical prose, to carry out a linguistic analysis of portrait descriptions in the stories "My Wanderings" and to identify the specifics and functions of the vestial vocabulary. In the study, the emphasis was placed on understanding the features of the writer's style, the specifics of his portraits, the ethnolinguistic and etymological aspect of the clothing vocabulary.

As a result of the analysis, it was revealed that in the autobiographical prose of V.A. Gilyarovsky, the main type of portrait is socio-historical, descriptive and everyday. Based on artistic tasks, the writer does not strive to comprehend the psychology of the characters or their rare individuality. There is no author's commentary in the portrait. The principles of the external image become fundamental. The "masculine" vision of the surrounding people leads to a lack of positive or negative expression, exaltation of feelings or sentimentality.

Civil uniform, frock coat, tailcoat, livery in portraits have not only a descriptive function, "visualizing" the hero, but also reveal the position of the hero, determine his personal attitude to his own position in society. Uniform, overcoat, caps, boots represent uniforms, where the definitions emphasize the material, insignia, style and details of clothing; awards. This vocabulary is also of a historical and archaic nature, allowing the reader to imagine the features of the costume of the 19th century, to immerse themselves in an interesting, unknown, sometimes patriarchal world, which contributes to understanding the environment, its hierarchy and, at the same time, picturesque diversity.

Female portraits with vestial vocabulary are rare; they perform a descriptive function, a function of social characterization. The legal requirement to wear official and particular dress is observed by officials who serve as heroes.

The change in fashion, associated not only with the aesthetic, but also with the ideological and political views of the revolutionary youth, their desire to democratize their appearance, is shown by the portrait of the exiles, where the vocabulary of folk clothes, in particular, the appearance of urban workers, prevails. At the same time, accessories emphasize the "subculture" of nihilists.
Ways to Neutralize Gender Attribution of Phraseological Units (Based on Media Texts)
Authors: Bespalova E. A.
Published: August 2023

The article is devoted to the analysis of cases of neutralization of gender attribution of phraseological units in their live use in modern media speech. Russian Russian phraseology The aim of the work is to study the dynamics of ideas about the masculine and feminine gender in Russian phraseology based on the identification of forms of neutralization of gender attribution, their classification and analysis of the noted transformations when using stable combinations in newspaper texts of the National Corpus of the Russian language. The following research methods are used in the work: continuous sampling method, observation of language material, lexicographic, lexico-semantic and contextual analysis, classification, analysis, generalization. Three ways of neutralization of gender attribution of phraseological units are considered: neutralization of gender at the level of dictionary definitions (indication of kinship with a person as a whole, without gender differentiation: Ivan, who does not remember kinship), neutralization at the grammatical level (compatibility with the object of the opposite grammatical gender: sleeping beauty), the use of phraseological turnover in relation to the person of the opposite pola (free Cossack). It is shown that, despite the strength of gender stereotypes in the linguistic consciousness, they are not frozen: gender representations change in the process of social development, which is expressed in the transformation of semantics and the compatibility of gender-marked phraseological units, rethinking their one-line connection with masculinity / femininity.

The identification of ways to neutralize the gender attribution of phraseological units contributes to the study of gender manifestations in phraseology. The description of modern phraseological usage is important from the point of view of ascertaining the constancy in the linguistic consciousness of established gender stereotypes and shifts in their perception, as well as the accumulation of data on the mechanisms of functioning of idiomatics and the development of phraseological meaning.
Names Components as Part of Idioms and Proverbs: Language and Culture Peculiarities
Authors: Lazareva Y. V.
Published: August 2023

The relevance of the research is determined by the comprehensive analysis of idioms and paroemias function-ing in modern Russian language formulating the national character. The aim of the research is to identify the charac-teristic features typical for idioms and paroemias containing names component. The research methodology is based on an interdisciplinary approach and includes general scientific and special methods. The group of general scientific methods includes analysis and synthesis, as well as generalization to systematize theoretical and practical material. The special methods group includes the modeling method to identify specific linguistic and cultural properties of idi-oms and paroemias typical for Russian culture; the method of component analysis to provide semantic features anal-ysis and to give lexical and semantic variants of words with several meanings; a definitional method to obtain lexico-graphic information dealing with the meaning of the language unit. Russian idioms and paroemias with Names com-ponents reflect the specific features of the national Russian character and make it possible to determine the key properties of the Russian mentality. The research deals with the analyses idioms and paroemias with the Names component having been divided into the following group types: mythonyms, chrononyms, hagionyms, literary onyms, historical onyms, anthroponyms. According to the author, all types of idioms and paroemias with the Name compo-nent function in modern Russian and are markers of culturally significant information reflecting the specifics of Rus-sian culture. All in all, the authors rank anthroponyms as the most productive Name components types, while chrono-nyms are not a productive phenomenon.