bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical and Similarity Simulation Study on the Protection Effect of Composite Protective Layer Mining with Gently Inclined Thick Coal Seam
Authors: Ma Jianhong , Hou Chao , Hou Jiangtao
Published: March 2021

Protective layer mining, as a dominating method for preventing coal and gas outburst, is generally adopted in highly gassy coal mines. In the absence of a suitable thickness coal seam to serve as the protective layer, the rock‐coal composite protective layer was proposed in this paper. We conducted a series of simulations and engineering measurements to investigate the protective effect under the mining of the rock‐coal composite protective layer of the Zhongtai coal mine located in the Hebi area of Henan, China. The numerical simulation analysis showed that, after the completion of protective layer mining, the minimum vertical stress of the No. 2‐1 coal seam had been reduced to 3.46 MPa. The maximum vertical displacement of the No. 2‐1 coal seam is 455.01 mm. The maximum expansion deformation of the No. 2‐1 coal seam is 9.77‰; the effective pressure relief range is as long as 160 m. The similarity simulation experiment revealed that, after the completion of protective layer mining, the minimum vertical stress of the No. 2‐1 coal seam is 4.0 MPa. The maximum vertical displacement of the No. 2‐1 coal seam is 640 mm. The maximum expansion deformation of the No. 2‐1 coal seam is 26.37‰; the effective protection range reaches 130 m. The engineering measurements demonstrated that the variation law of gas drainage parameters in the protected layer corresponds to the protected layer′s vertical stress distribution law in numerical simulation and similarity simulation. With the exploitation of the composite protective layer, the protective layer’s pressure begins to release. The average gas drainage concentration is 2‐3 times of that before the composite protective layer mining.
Improving the Moisture Sensitivity of Asphalt Mixtures by Simultaneous Modification of Asphalt Binder and Aggregates with Carbon Nanofiber and Carbon Nanotube
Authors: Nikookar Mohammad , Bagheri Movahhed Mojtaba , Ayoubinejad Jalal , Najafi Moghaddam Gilani Vahid , Hosseinian Seyed Mohsen
Published: March 2021

Moisture sensitivity of asphalt mixtures may cause damage due to cohesion in asphalt binder membrane and adhesion between aggregate and asphalt binder that result in considerable damage to the pavements. Therefore, by determining the adhesion quality in a modified aggregate‐asphalt binder system, one can choose the suitable material compositions to decrease the moisture sensitivity of mixtures. In this study, the effects of modified asphalt binder with carbon nanofiber and modified aggregates with carbon nanotube on the moisture sensitivity of asphalt mixtures were simultaneously explored. For investigating the moisture sensitivity, the indirect tensile strength test and surface free energy concept were implemented. The results of the indirect tensile strength test revealed that modification of asphalt binder and aggregates with carbon nanofiber and carbon nanotube, respectively, increased the indirect tensile strength and tensile strength ratio values of mixtures. The results of surface free energy indicated that using carbon nanofiber and carbon nanotube enhanced the adhesion free energy of the aggregate‐asphalt binder system. Moreover, utilizing carbon nanofiber to modify asphalt binder enhanced the cohesion free energy values in the asphalt binder membrane. Also, carbon nanofiber and carbon nanotube brought detachment energy of the system toward zero, indicating less desire for the mixtures to be stripped. Generally, investigations performed by the two methods showed that covering aggregates by carbon nanotube as well as utilizing carbon nanofiber as an asphalt binder modifier had a positive impact on decreasing moisture sensitivity of asphalt mixtures.
Application of Infusion Control System Based on Internet of Things Technology in Joint Orthopedics Nursing Work
Authors: Bai Xia , Wang Qiaoli , Cao Shengqin
Published: March 2021

In recent years, the Internet of Things technology has flourished, and there have been corresponding practical results in various fields. In medical care, the introduction of Internet of Things technology must also be a new trend in the development of hospital informatization, and it is the development stage of the digital medical process. The traditional infusion system shows that the infusion bottle is not replaced in time, the infusion waiting time is too long, the infusion efficiency is too low, and the existing medical staff is far from meeting the needs of the huge infusion population. Therefore, this article proposes a technology based on the Internet of Things application of the infusion control system in joint orthopedics nursing work to improve the efficiency of infusion in nursing work. This article deeply learns and uses the Internet of Things technology to build a new infusion management and control system, which is applied to joint orthopedics nursing treatment. This paper designs the application research experiment of the infusion control system. Through the Internet of Things technology, the relevant data in the infusion process are uploaded and sent to the network center of the hospital. Nursing staff can directly see the infusion situation directly through the computer console. This article compares and analyzes two different infusion systems and draws conclusions. The infusion ringing rate of the control group was 81.3%, and the infusion ringing rate of the IoT group was 29.8%; the time for timely replacement of the infusion bottle after IoT data control was 13.89 min, compared to 19.76 min before. A variety of data results show that the infusion management and control system based on the Internet of Things technology has played a great role in joint orthopedics care, which can greatly improve the efficiency of infusion, replace the infusion or deal with failures in time for patients, and improve patient satisfaction.
Mechanism and Procedure of Repeated Borehole Drilling Using Wall Protection and a Soft Structure to Prevent Rockburst: A Case Study
Authors: He Yongliang , Gao Mingshi , Dong Xu , Yu Xin
Published: March 2021

With the increasing mining depth of coal mines, the occurrence of rockburst, especially in mine roadways, is becoming critical as a severe dynamic disaster. This paper explores the stability control of deep mine roadways and solves the contradiction between the support and pressure relief of roadways by studying the use of an internal steel pipe for wall protection and a soft structure for energy absorption during repeated borehole drilling. Numerical simulations are performed to examine the effects of active support technology on the support structure during repeated drilling. Internal steel pipes can effectively prevent the support structure from being damaged. When the soft structure cracks, the energy transmitted from the rockburst to the roadway is significantly reduced. According to the deformation and failure characteristics of the surrounding rock of the 21170 roadway, the combination of anchor active support, hydraulic lifting shed support, and soft structure energy absorption is proposed. An engineering case study shows that the support method can effectively maintain the stability of the surrounding rock and ensure the safe mining of the working face. The proposed control method can provide reference for the prevention and control of rockburst in mine roadways under similar geological conditions.
Potential Alteration of Statin‐Related Pharmacological Features in Diabetes Mellitus
Authors: Mashayekhi-Sardoo Habibeh , Atkin Stephen L. , Montecucco Fabrizio , Sahebkar Amirhossein
Published: March 2021

Objective. Type 2 diabetes mellitus is a chronic metabolic disease caused by insulin resistance or insulin deficiency resulting in elevated blood glucose levels. Poorly controlled diabetes is associated with the development of cardiovascular disease and dyslipidemia. 3‐Hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase inhibitors (statin) are an important class of therapeutic agents used to control hyperlipidemia and prevent cardiovascular disease in diabetic and nondiabetic patients. Since the effect of diabetes on the pharmacokinetics and pharmacodynamics of drugs and toxins has been shown, the aim was to review previous studies on the efficacy of statins such as atorvastatin, simvastatin, pravastatin, pitavastatin, fluvastatin, and rosuvastatin in clinical and preclinical studies in both diabetic and nondiabetic groups. Method. For this purpose, Web of Science, PubMed, Scopus, and Google Scholar databases were reviewed, and related English articles published until October 2020 were included in this review article. Results. The findings revealed that diabetes affected statin effectiveness through changes in pharmacokinetic parameters such as clearance and biotransformation biomarkers at mRNA and protein levels. Plasma and serum concentrations of statins were accompanied by alteration in cellular activities including oxidative stress, Akt inhibition, and endothelial nitric oxide synthase (eNOS) and phosphorylation that were reflected in changes in the adverse drug reaction profile of the differing statins. Conclusion. Given that dyslipidemia frequently accompanies diabetes and statin therapy is common, more clinical studies are needed regarding the effects of diabetes on the effectiveness of these drugs.
Automatic Identification and Location of Tunnel Lining Cracks
Authors: Wang Pengyu , Wang Shuhong , Jierula Alipujiang
Published: March 2021

The lining crack is common for the tunnel in the stage of operation, which has seriously influenced the service life and safety of tunnel engineering. It is a new trend to use computer vision to detect tunnel cracks over the past few years in China and foreign countries. By image processing technology and intelligent algorithm, the computer has a hominine visual perception system which understands, analyzes, and determines input image information, thus recognizing and detecting specific objectives. However, the effect of image recognition for tunnel crack now cannot satisfy the demands of practical engineering. SSD algorithm has been used when analyzing features of lining surface image, while comparison analysis has been made from image recognition results, error rate, and running time. The results indicate that the SSD algorithm can accurately and rapidly detect and mark the position of the tunnel crack. The tunnel information obtained from image recognition is subsequently imported into the team independently developed software GeoSMA‐3D, which is useful for determining tunnel grade.
Kinematic Calibration of Industrial Robots Based on Distance Information Using a Hybrid Identification Method
Authors: Gao Guanbin , Li Yuan , Liu Fei , Han Shichang
Published: March 2021

To improve the positioning accuracy of industrial robots and avoid using the coordinates of the end effector, a novel kinematic calibration method based on the distance information is proposed. The kinematic model of an industrial robot is established. The relationship between the moving distance of the end effector and the kinematic parameters is analyzed. Based on the results of the analysis and the kinematic model of the robot, the error model with displacements as the reference is built, which is linearized for the convenience of the following identification. The singular value decomposition (SVD) is used to eliminate the redundant parameters of the error model. To solve the problem that traditional optimization algorithms are easily affected by data noise in high dimension identification, a novel extended Kalman filter (EKF) and regularized particle filter (RPF) hybrid identification method is presented. EKF is used in the preidentification of the linearized error model. With the preidentification results as the initial parameters, RPF is used to identify the kinematic parameters of the linearized error model. Simulations are carried out to validate the effectiveness of the proposed method, which shows that the method can identify the error of the parameters and after compensation the accuracy of the robot is improved.
E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Authors: González-Romero Francisco , Mestre Daniela , Aurrekoetxea Igor , O'Rourke Colm J. , Andersen Jesper B. , Woodhoo Ashwin , Tamayo-Caro Miguel , Varela-Rey Marta , Palomo-Irigoyen Marta , Gómez-Santos Beatriz , de Urturi Diego Sáenz , Núñez-García Maitane , García-Rodríguez Juan L. , Fernández-Ares Larraitz , Buqué Xabier , Iglesias-Ara Ainhoa , Bernales Irantzu , De Juan Virginia Gutierrez , Delgado Teresa C. , Goikoetxea-Usandizaga Naroa , Lee Richard , Bhanot Sanjay , Delgado Igotz , Perugorria Maria J. , Errazti Gaizka , Mosteiro Lorena , Gaztambide Sonia , Martinez de la Piscina Idoia , Iruzubieta Paula , Crespo Javier , Banales Jesus M. , Martínez-Chantar Maria L. , Castaño Luis , Zubiaga Ana M. , Aspichueta Patricia
Published: March 2021

Lipid metabolism rearrangements in nonalcoholic fatty liver disease (NAFLD) contribute to disease progression. NAFLD has emerged as a major risk for hepatocellular carcinoma (HCC), where metabolic reprogramming is a hallmark. Identification of metabolic drivers might reveal therapeutic targets to improve HCC treatment. Here, we investigated the contribution of transcription factors E2F1 and E2F2 to NAFLD-related HCC and their involvement in metabolic rewiring during disease progression. In mice receiving a high-fat diet (HFD) and diethylnitrosamine (DEN) administration, E2f1 and E2f2 expressions were increased in NAFLD-related HCC. In human NAFLD, E2F1 and E2F2 levels were also increased and positively correlated. E2f1−/− and E2f2−/− mice were resistant to DEN–HFD-induced hepatocarcinogenesis and associated lipid accumulation. Administration of DEN–HFD in E2f1−/− and E2f2−/− mice enhanced fatty acid oxidation (FAO) and increased expression of Cpt2, an enzyme essential for FAO, whose downregulation is linked to NAFLD-related hepatocarcinogenesis. These results were recapitulated following E2f2 knockdown in liver, and overexpression of E2f2 elicited opposing effects. E2F2 binding to the Cpt2 promoter was enhanced in DEN–HFD-administered mouse livers compared with controls, implying a direct role for E2F2 in transcriptional repression. In human HCC, E2F1 and E2F2 expressions inversely correlated with CPT2 expression. Collectively, these results indicate that activation of the E2F1–E2F2–CPT2 axis provides a lipid-rich environment required for hepatocarcinogenesis.

Significance:

These findings identify E2F1 and E2F2 transcription factors as metabolic drivers of hepatocellular carcinoma, where deletion of just one is sufficient to prevent disease.
The Shared Genetic Architectures Between Lung Cancer and Multiple Polygenic Phenotypes in Genome-Wide Association Studies
Authors: Byun Jinyoung , Han Younghun , Ostrom Quinn T. , Edelson Jacob , Walsh Kyle M. , Pettit Rowland W. , Bondy Melissa L. , Hung Rayjean J. , McKay James D. , Amos Christopher I.
Published: March 2021

Background:

Prior genome-wide association studies have identified numerous lung cancer risk loci and reveal substantial etiologic heterogeneity across histologic subtypes. Analyzing the shared genetic architecture underlying variation in complex traits can elucidate common genetic etiologies across phenotypes. Exploring pairwise genetic correlations between lung cancer and other polygenic traits can reveal the common genetic etiology of correlated phenotypes.

Methods:

Using cross-trait linkage disequilibrium score regression, we estimated the pairwise genetic correlation and heritability between lung cancer and multiple traits using publicly available summary statistics. Identified genetic relationships were also examined after excluding genomic regions known to be associated with smoking behaviors, a major risk factor for lung cancer.

Results:

We observed several traits showing moderate single nucleotide polymorphism–based heritability and significant genetic correlations with lung cancer. We observed highly significant correlations between the genetic architectures of lung cancer and emphysema/chronic bronchitis across all histologic subtypes, as well as among lung cancer occurring among smokers. Our analyses revealed highly significant positive correlations between lung cancer and paternal history of lung cancer. We also observed a strong negative correlation with parental longevity. We observed consistent directions in genetic patterns after excluding genomic regions associated with smoking behaviors.

Conclusions:

This study identifies numerous phenotypic traits that share genomic architecture with lung carcinogenesis and are not fully accounted for by known smoking-associated genomic loci.

Impact:

These findings provide new insights into the etiology of lung cancer by identifying traits that are genetically correlated with increased risk of lung cancer.
Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells
Authors: Lim Ji-Young , Kim Tae-Woo , Ryu Da-Bin , Park Sung-Soo , Lee Sung-Eun , Kim Byung-Soo , Min Chang-Ki
Published: March 2021

Progression of multiple myeloma is regulated by factors intrinsic to the clonal plasma cells (PC) and by the immune effector cells in the tumor microenvironment. In this study, we investigated the interaction between CD304 expression on myeloid-derived suppressor cells (MDSC) and galectin-1 from malignant PCs in the context of autologous stem cell transplantation (ASCT) for multiple myeloma. Using high-throughput screening, CD304 expression on circulating monocytic MDSCs (M-MDSC; CD14+HLA-DRlow/−) was compared before and after ASCT. There was a significantly higher M-MDSC expression of CD304 before ASCT and a clear correlation between circulating pre-ASCT M-MDSC frequency and serum galectin-1 concentration. Treatment of pre-ASCT M-MDSCs, but not post-ASCT M-MDSCs, with galectin-1 in vitro expanded the M-MDSC population and increased expression of CD304. High galectin-1 expression by malignant PCs was associated with poor clinical outcomes. M-MDSC development and expression of CD304 were differentially induced when healthy donor peripheral blood mononuclear cells were cultured with the human multiple myeloma cell lines RPMI-8226 and JJN3, which express high and low galectin-1, respectively. Inhibition of galectin-1 reduced M-MDSC proliferation induced by RPMI-8226 cells but not by JJN3 cells, and blockade of CD304 reduced M-MDSC migration induced by RPMI-8226 cells but not by JJN3 cells. In addition, blockade of CD304 reversed suppression of the in vitro cytotoxic effect of melphalan by pre-ASCT M-MDSCs. Our data demonstrate that multiple myeloma–derived galectin-1 could mediate the tumor-promoting effect of M-MDSCs through its interaction with CD304 on M-MDSCs and contribute to multiple myeloma progression after ASCT.

See related Spotlight on p. 488
Towards Modelling Genetic Kidney Diseases with Human Pluripotent Stem Cells
Authors: Rooney Kirsty M. , Woolf Adrian S. , Kimber Susan J.
Published: March 2021

Background: Kidney disease causes major suffering and premature mortality worldwide. With no cure for kidney failure currently available, and with limited options for treatment, there is an urgent need to develop effective pharmaceutical interventions to slow or prevent kidney disease progression. Summary: In this review, we consider the feasibility of using human pluripotent stem cell-derived kidney tissues, or organoids, to model genetic kidney disease. Notable successes have been made in modelling genetic tubular diseases (e.g., cystinosis), polycystic kidney disease, and medullary cystic kidney disease. Organoid models have also been used to test novel therapies that ameliorate aberrant cell biology. Some progress has been made in modelling congenital glomerular disease, even though glomeruli within organoids are developmentally immature. Less progress has been made in modelling structural kidney malformations, perhaps because sufficiently mature metanephric mesenchyme-derived nephrons, ureteric bud-derived branching collecting ducts, and a prominent stromal cell population are not generated together within a single protocol. Key Messages: We predict that the field will advance significantly if organoids can be generated with a full complement of cell lineages and with kidney components displaying key physiological functions, such as glomerular filtration. The future economic upscaling of reproducible organoid generation will facilitate more widespread research applications, including the potential therapeutic application of these stem cell-based technologies.
Higher Mortality of Ischaemic Stroke Patients Hospitalized with COVID-19 Compared to Historical Controls
Authors: Harrison Stephanie L. , Fazio-Eynullayeva Elnara , Lane Deirdre A. , Underhill Paula , Lip Gregory Y.H.
Published: March 2021

Introduction: Increasing evidence suggests patients with coronavirus disease 2019 (COVID-19) may develop thrombosis and thrombosis-related complications. Some previous evidence has suggested COVID-19-associated strokes are more severe with worse outcomes for patients, but further studies are needed to confirm these findings. The aim of this study was to determine the association between COVID-19 and mortality for patients with ischaemic stroke in a large multicentre study. Methods: A retrospective cohort study was conducted using electronic medical records of inpatients from 50 healthcare organizations, predominately from the USA. Patients with ischaemic stroke within 30 days of COVID-19 were identified. COVID-19 was determined from diagnosis codes or a positive test result identified with CO­VID-19-specific laboratory codes between January 20, 2020, and October 1, 2020. Historical controls with ischaemic stroke without COVID-19 were identified in the period January 20, 2019, to October 1, 2019. 1:1 propensity score matching was used to balance the cohorts with and without CO­VID-19 on characteristics including age, sex, race and comorbidities. Kaplan-Meier survival curves for all-cause 60-day mortality by COVID-19 status were produced. Results: During the study period, there were 954 inpatients with ischaemic stroke and COVID-19. During the same time period in 2019, there were 48,363 inpatients with ischaemic stroke without COVID-19 (historical controls). Compared to patients with ischaemic stroke without COVID-19, patients with ischaemic stroke and COVID-19 had a lower mean age, had a lower prevalence of white patients, a higher prevalence of black or African American patients and a higher prevalence of hypertension, previous cerebrovascular disease, diabetes mellitus, ischaemic heart disease, atrial fibrillation, chronic kidney disease, chronic obstructive pulmonary disease, liver disease, neoplasms, and mental disorders due to known physiological conditions. After propensity score matching, there were 952 cases and 952 historical controls; cases and historical controls were better balanced on all included characteristics (all p > 0.05). After propensity score matching, Kaplan-Meier survival analysis showed the survival probability was significantly lower in ischaemic stroke patients with COVID-19 (78.3% vs. 91.0%, log-rank test p < 0.0001). The odds of 60-day mortality were significantly higher for patients with ischaemic stroke and COVID-19 compared to the propensity score-matched historical controls (odds ratio: 2.51 [95% confidence interval 1.88–3.34]). Discussion/Conclusions: Ischaemic stroke patients with COVID-19 had significantly higher 60-day all-cause mortality compared to propensity score-matched historical controls (ischaemic stroke patients without COVID-19).
Relation between Baseline Coronary Atherosclerotic Status, Cardiovascular Events, and Malignancies in Type 2 Diabetics: A Long-Term Prospective Cohort Study
Authors: Azencot Mali , Lewis Basil S. , Halon David A.
Published: March 2021

Introduction: Coronary artery disease and malignancy occur more frequently in patients with type 2 diabetes. They may share inflammation as a possible common pathogenetic mechanism, but it is unclear whether a clinical correlation exists between them. Methods: This prospective cohort study followed 735 asymptomatic diabetics, aged 63.4 ± 5.3 years (mean ± standard deviation) for 12.2 ± 0.6 years after baseline coronary artery calcium scoring and cardiac computed tomography angiography. We examined extent and nature of coronary atherosclerosis and incidence of clinical cardiovascular (CV) events (death or myocardial infarction) and sought a relation to incidence of malignancy and malignancy mortality. Results: Total mortality was 16.5% (121/735 patients): malignancy was cause of death in 48/121 (39.7%) of these and CV events in 44/121 (36.3%). There was no relation between extent of coronary atherosclerosis and incident malignancy (plaque volume 127 [21, 427] mm3 (median [interquartile range]) for incident malignancy versus 153 [24, 427] mm3 no malignancy, p = 0.71) or death from malignancy (plaque volume 176 [26, 646] versus 144 [22, 411] mm3, p = 0.32). There was also no relation between presence of high-risk plaque and incident malignancy (high-risk plaque in 27.1% with malignancy vs. 21.6% without, p = 0.18) or fatal malignancy (p = 0.16). Incident and fatal malignancy were not related to clinical CV events. Independent predictors of incident and fatal malignancy were age, smoking at baseline, and elevated C-reactive protein. Conclusion: This study found no relation between extent of coronary atherosclerosis or incidence of CV events and malignancy. Malignancy surpassed CV disease as the commonest long-term cause of mortality in middle-aged and older diabetics.
Effect of a Home-Based Exercise Program on Indices of Physical Function and Quality of Life in Elderly Maintenance Hemodialysis Patients
Authors: Myers Jonathan , Chan Khin , Chen Yu , Lit Yiming , Patti Alessandro , Massaband Payam , Kiratli B. Jenny , Tamura Manju , Chertow Glenn M. , Rabkin Ralph
Published: March 2021

Background: Patients on maintenance hemodialysis (MHD) exhibit muscle wasting and impaired physical function which can be reversed with regular exercise, but accessibility to exercise programs for this unique population is lacking. We assessed the efficacy of a home-based exercise program on a broad range of indices of physical function, quality of life (QoL), and cognitive decline in patients with MHD. Design and Methods: Twenty-eight MHD patients, mean age 66 ± 7 years, were randomized to a 12-week home-based, case-managed aerobic and resistance exercise program or to usual care (13 exercise and 15 usual care). Comparisons were made for peak VO2, ventilatory inefficiency, 6-min walk test (6MWT), 1-min sit-to-stand (1STS), muscle strength, body composition, QoL, and cognitive measures. Results: Peak VO2 improved significantly in the exercise group (p = 0.01 between groups); exercise time improved by 41 and 36% at the ventilatory threshold and peak exercise, respectively (p < 0.01 between groups), but there were no differences in ventilatory efficiency. Trends for improvements in 6MWT and 1STS in the exercise group were observed, but no differences were observed in strength or body composition. Among measures of QoL, general health determined by the SF-36 improved in the exercise group, but there were no differences between groups in cognitive function. Conclusions: MHD patients improved exercise capacity and some indices of QoL following a 12-week home-based exercise program. Home-based exercise is feasible for patients undergoing MHD and may help to obviate accessibility barriers to regular exercise.
Dementia Care Apps for People with Dementia and Informal Caregivers: A Systematic Review Protocol
Authors: Ye Bing , How Tuck-Voon , Chu Charlene H. , Mihailidis Alex
Published: March 2021

Dementia drastically impacts the quality of life (QOL) of both people living with dementia (PLwD) and their family caregivers. As dementia progresses and care needs escalate, the likelihood of institutionalization is increased, which is counter to the wishes of the majority of older adults and their family members. Dementia care apps can provide critical support and have the potential to improve the QOL of both PLwD and their family caregivers and reduce perceived caregivers’ burden. However, there is a lack of understanding of the needs of both PLwD and their family caregivers related to dementia care apps. There is also a gap in understanding the privacy concerns in relation to the apps among older adults with dementia and their caregivers. As such, the main aims of this systematic review are to understand the landscape of dementia mobile apps targeting PLwD and their caregivers with respect to the features of the apps, usability testing, and the privacy and security aspects of the app from the perspective of both app developers/researchers and the end users (PLwD and family caregivers who provide care of PLwD). Extensive databases, including ACM Digital Library, Cochrane Central Register of Controlled Trials, Compendex, Embase, Inspec, Ovid MEDLINE(R) Daily, Proquest Dissertations and These Global, PsycINFO, and Scopus, have been searched. All searches are from the inception of the databases. All peer-reviewed studies and articles written in the English language are included. Two reviewers will independently screen and select the studies with the involvement of a third reviewer for disagreements. Data will be abstracted using a custom data extraction form that is made based on the research questions. Critical Appraisal Skills Programme (CASP) checklists will be used to assess the study quality. As the first review of its kind, the findings from this review will provide valuable insights related to the needs of the dementia care apps for both PLwD and their family caregivers. The review will be relevant to health providers who are interested in using technologies to promote the independence of PLwD and reduce the stress experienced from caregivers of PLwD. The review will also serve as a guide to app developers and researchers to design usable and acceptable apps. In addition, the review will provide critical knowledge of the privacy and security features of the app to reveal the valid concerns from the end users and thus help with the uptake and adoption of the dementia care apps.
Will We Soon Run Out of Water?
Authors: de Marsily Ghislain
Published: March 2021

In 2000, the World population was 6.2 billion; it reached 7 billion in 2012 and should reach 9.5 billion (±0.4) in 2050 and 11 billion (±1.5) in 2100, according to UN projections. The trend after 2100 is still one of global demographic growth, but after 2060, Africa would be the only continent where the population would still increase. The amount of water consumed annually to produce the food necessary to meet the needs varies greatly between countries, from about 600 to 2,500 m3/year per capita, depending on their wealth, their food habits (particularly meat consumption), and the percentage of food waste they generate. In 2000, the total food production was on the order of 3,300 million tons (in cereal equivalents). In 2019, about 0.8 billion inhabitants of the planet still suffer from hunger and do not get the nutrition they need to be in good health or, in the case of children, to grow properly (both physically and intellectually). Assuming a World average water consumption for food of 1,300 m3/year per capita in 2000, 1,400 m3/year in 2050, and 1,500 m3/year in 2100, a volume of water of around 8,200 km3/year was needed in 2000, 13,000 km3/year will be needed in 2050, and 16,500 km3/year in 2100. Will that much water be available on earth? Can there be conflicts related to a food deficit? Some preliminary answers and scenarios for food production will be given from a hydrologist viewpoint.
What's Happened to Poverty and Inequality in Indonesia over Half a Century?
Authors: Hill Hal
Published: March 2021

Indonesia has achieved moderately fast economic growth for most of the past 50 years. Has this growth translated into rising living standards? This is the question that is addressed in this paper. The conclusion is a qualified yes. The caveat is attached for two reasons: (i) philosophically, the definition of living standards remains a subject of considerable conjecture, and (ii) not all social indicators point in the same direction. I focus primarily on trends in measurable indicators of human welfare, particularly poverty and inequality. Combined with major improvements in the coverage and quality of the country's statistics, and a now extensive literature, it is possible to document, and in some cases explain, trends in living standards in some detail. I also investigate whether (and how) the sudden swing during 1999–2001 from an authoritarian and centralized regime to a democratic and decentralized era impacted significantly on these trends.
Jewish Humanism in the Late Work of Geoffrey Hill
Authors: Russell Jesse
Published: March 2021

Throughout much of his career, Geoffrey Hill has been pilloried for his alleged conservativism as well as his positive treatment of Christianity in his poetry. A careful reading of his works, however, reveals a complex thinker who was attentive to the moral fallout of the Holocaust and the Second World War as he was a lover of England and European culture. Moreover, Hill’s writings reflect the apparent influence of a host of personalist, existentialist and what could also be called “humanist” twentieth century Jewish thinkers such as Martin Buber and Emmanuel Levinas. Throughout his poetry—especially his later work—Hill attempts (whether successfully or not) to fuse together this Jewish humanism with his own Christian and English voice.
Deeds, Reward, and Divine Mercy: Jewish Views and Pauline Passages
Authors: Kister Menahem
Published: March 2021

The present article deals with a strand of ancient Jewish theological notions (in rabbinic literature, Fourth Ezra, and elsewhere) and Pauline ones. In these Jewish passages—sharing similar religious sensitivities and using similar terminology—human works stand vis-à-vis God’s mercy and his benevolence (צדקה). In some passages these categories turn out to be in tension in view of human sinfulness, since no human being can comply with the rigid standards of observing God’s commandments, resulting in the emphasis of divine mercy. Paul’s view, according to which “works (of the law)” and “grace” are mutually exclusive, is a radical intensification of this tension. Paul’s distinct ideas display the inherent dynamics of contemporary Jewish notions and reveal the inner tension within Jewish thought of the late Second Temple period, a tension that continued in Jewish writings (including rabbinic literature) after the Second Temple’s destruction.
The Sacramental Ontology of the Church
Authors: Davis Melissa
Published: March 2021

This article seeks to construct a renewalist ecclesiology foundations on the idea that the church is an ontological reality with the epistemological purpose of traditioning its members. To accomplish this, I construct, in conversation with Simon Chan and Simon Oliver, a sacramental ontology of the invisible church from the Garden of Eden via the incarnation. Then, interacting with the work of Chan and James K.A. Smith, I explore the role of the visible church to tradition its members. Finally, I offer a framework for an ecclesial traditioning praxis. This praxis is founded in prayer, shaped by the narrative of Scripture, and utilizes both the weekly service and ongoing discipleship training.
In the eye of the storm
Authors: Walsh Edward J. , Fairall C. W. , PopStefanija Ivan
Published: March 2021

The airborne NOAA Wide Swath Radar Altimeter (WSRA) is a 16 GHz digital beamforming radar altimeter that produces a topographic map of the waves as the aircraft advances. The wave topography is transformed by a two-dimensional FFT into directional wave spectra. The WSRA operates unattended on the aircraft and provides continuous real-time reporting of several data products: (1) significant wave height, (2) directional ocean wave spectra, (3) the wave height, wavelength, and direction of propagation of the primary and secondary wave fields, (4) rainfall rate and (5) sea surface mean square slope (mss). During hurricane flights the data products are transmitted in real-time from the NOAA WP-3D aircraft through a satellite data link to a ground station and on to the National Hurricane Center (NHC) for use by the forecasters for intensity projections and incorporation in hurricane wave models. The WSRA is the only instrument that can quickly provide high-density measurements of the complex wave topography over a large area surrounding the eye of the storm.
Jubilate: a conversation about Prayer Book revision and the language of our prayer
Authors: Meyers Ruth A. , Sonderegger Katherine
Published: March 2021

These essays were presented at the Jubilate conference at Christ Church Cathedral in the Diocese of Southern Ohio on 2 November 2019. Meyers urges the expansion of images and metaphors used to speak of the mystery of God in liturgy while not abandoning classical masculine language for God. Expanding our language is essential, she argues, both to speak the truth about God and to uphold the dignity of every human being. Sonderegger contends that masculine language for God is a settled matter in the church and in liturgy, and that this is compatible with a particular vision of Christian feminism, one centered on the material conditions of living women.
Evaluation of college English classroom teaching quality dependent on triangular fuzzy number
Authors: Xie Zhixian , Su Zheqian
Published: March 2021

With economic globalization and the informatization of social life, English has become a language extensively used around the globe. The research on the evaluation of English teaching quality is of crucial practical significance and theoretical value. Hence, student evaluation form for the college English classroom teaching quality that has been evaluated and has good reliability is used in this paper to expound the principles of the triangular fuzzy number evaluation method and the range method based on the analytic hierarchy process (AHP). Examples are used to analyze the differences between the two methods as well as their advantages and disadvantages. The comprehensive evaluation result of the teaching quality evaluation of a teacher by using the range method is excellent (85.500 points), and the comprehensive evaluation result by using the triangular fuzzy number method based on the analytic hierarchy process is good (64.818 points). The results show that the range method is better for the comprehensive evaluation of teachers' teaching quality. The statistical analysis results suggest that there are differences between the two methods in the evaluation of the classroom teaching quality in colleges and universities (t = 11.197, P < 0.0001). In the evaluation of the teaching quality by using the triangular fuzzy number evaluation method based on the analytic hierarchy process, the non-linear and fuzzy features of evaluation factors are taken into consideration comprehensively. The weight values of various evaluation indexes are calculated scientifically. The qualitative and quantitative evaluations are combined to obtain the evaluation result of the classroom teaching quality of teachers more objectively, which is of great significance in the practical teaching quality evaluation process.
An Adlerian-Based Empowering Intervention Program With Burned-Out Teachers
Authors: Ghasemi Farshad
Published: March 2021

We examined the effects of an intervention program based on Adlerian psychology on the burned-out teachers. By administering the Maslach Burnout Inventory (MBI) and the Achievement Motivation Test (AMT), we identified 60 teachers with burnout symptoms. The experimental group attended eight sessions of the intervention program with different cognitive restructuring techniques and motivational themes to facilitate psychological empowerment. The findings demonstrated the positive effects of the program on alleviating burnout with cognitive and behavioral changes in the participants’ personal and professional lives. The durability of these improvements was moderate at a 6-month follow-up after the intervention.
Creating Virtual Ensembles: Common Approaches from Research and Practice
Authors: Cayari Christopher
Published: March 2021

A virtual ensemble is a digital musical product that uses multiple recordings edited together to form a musical ensemble. Creating virtual ensembles can be a way for music educators to engage students through online music-making. This article presents eight steps for creating virtual ensembles in music education courses and classrooms. The steps are (1) identifying objectives and desired outcomes, (2) selecting repertoire, (3) developing learning resources, (4) creating an anchor for synchronizing, (5) choosing a recording method, (6) setting up a collection platform, (7) editing in postproduction, and (8) distributing the product. As online music production becomes more prevalent, projects like virtual ensembles can provide creative and exciting experiences for music teachers and students, whether produced in the classroom or through remote means on the Internet.
Psychometric Properties of a French Version of the Perceived Motor Competence in Childhood Questionnaire
Authors: Maïano Christophe , Morin Alexandre J. S. , April Johanne , Tietjens Maike , St-Jean Charlaine , Gagnon Cynthia , Dreiskämper Dennis , Aimé Annie
Published: March 2021

In this study, we examined the psychometric properties of a French version of the Perceived Motor Competence in Childhood (PMC-C) questionnaire. The participants were 219 French-speaking children (aged 5-12 years), recruited from elementary schools in the Canadian Province of Quebec. Results supported the validity and reliability of a second-order confirmatory factor analytic (CFA) model, including one higher-order factor. Additional analyses supported the complete measurement invariance of the first- and second-order factor structure across sex and indicated no differential item functioning or latent mean differences in PMC-C factors as a function of selected predictors (i.e., age, body mass-index and physical activity/sport involvement). Thus, this French version of the PMC-C has satisfactory psychometric properties (i.e., factor validity and reliability, measurement invariance and differential item functioning) and can be used to assess French-speaking children’s perceived motor competence.
Key Factors for Successful Implementation of HIV Prevention Services by THRIVE Community Collaboratives
Authors: Tanner Mary R. , Iqbal Kashif , Dominguez Kenneth L. , Zhu Weiming , Obi Jane , Hoover Karen W.
Published: March 2021

Objective

The Targeted Highly Effective Interventions to Reverse the HIV Epidemic (THRIVE) demonstration project created collaboratives of health departments, community-based organizations, and clinical partners to improve HIV prevention services for men who have sex with men (MSM) and transgender women (TGW) of color. We administered an online survey from September 2018 through February 2019 to assess the collaboratives.

Methods

We used a Likert scale to measure agreement on collaborative characteristics. We used Fisher exact tests to compare success ratings by health department employment and funding status. We created a radar chart to compare the percentage agreement on key characteristics of the most and least successful collaboratives. We used a general inductive approach in the qualitative analysis of open-ended question responses.

Results

Of 262 survey recipients, 133 responded (51%); 49 (37%) respondents were from health departments. Most respondents (≥70%) agreed that their collaborative is diverse, cooperates, meets regularly, has realistic goals, has effective leadership, and has effective communication. Most respondents (87%) rated their collaborative as successful in implementing HIV prevention services for MSM and TGW of color. Comparison of the most and least successful collaborative found the greatest difference in respondent agreement in the presence of effective leadership, communication, and adequate resources. The most commonly cited challenge in the open-ended questions was inadequate resources. The most commonly cited success was increased provision of services, particularly preexposure prophylaxis.

Conclusions

Community collaboratives were considered successful by most collaborative members and may be an effective part of HIV prevention strategies.
Flexible Selves in Flexible Times? Yoga and Neoliberal Subjectivities in Istanbul
Authors: Erkmen T Deniz
Published: March 2021

This article adds to contemporary analyses of neoliberal subjectivities by focusing on middle-class yoga practitioners in Istanbul, Turkey. Drawing on in-depth interviews, it questions the dominant interpretation of yoga as a form of neoliberal governance and suggests that within the nexus of neoliberal globalisation, autocratisation and precarisation, practices that are often labeled ‘lifestyle consumption’ might provide individuals with the discursive tools to question entrepreneurial norms. Expanding the geographical scope of existing research as well as providing a theoretically informed analysis of empirical data, the article makes an original contribution to understandings of neoliberal subjectivities by bridging work on neoliberal subjectivities and lifestyle politics.
A rhythmanalysis approach to understanding the vending-walking forms and everyday use of urban street space in Yuncheng, China
Authors: Sun Ziwen
Published: March 2021

In Chinese cities, informal street vendors often appear in a transient space intertwined with a large number of pedestrians and heterogeneity, in contrast with the dichotomous construction of static built environment and dynamic street activity examined in most studies on walkability. This paper explores the rhythm of everyday street spaces and the temporary experiences of pedestrians and street vendors in Yuncheng, China. The author argues that street vendors are particularly well suited for capturing city rhythms and can discern the tempo of social life and pedestrians in urban street spaces. Following Lefebvre’s rhythmanalysis approach and drawing on 86 semi-structured interviews combined with on-site observation in three street spaces, this paper investigates how rhythms are linked to spatial form, time and the everyday street activity of walking and vending. It expands an analytical framework in both daily rhythms and long-standing rhythms, including arrhythmia, eurhythmia and polyrhythmia. The conclusions provide an alternative way of understanding why pedestrians emerge, through considering how street vendors temporarily meet the everyday needs of different pedestrians in specific, real and detailed ways. Such fine-grained narratives, in turn, demonstrate the need to advance theoretical and empirical understandings of multiple rhythms in relation to walkable space and walking forms.