bluuebunny/crossref_metadata_2025 huggingface dataset:
EDUCAÇÃO PARA O TRÂNSITO: metodologia e estratégias para atuação junto aos acadêmicos da universidade da maturidade na cidade de Araguaína/TO
Authors: Morais Cleide de Sousa , Osório Neila Barbosa
Published: June 2018

Com o aumento da expectativa de vida, deve-se compreender e conviver com idosos de maneira a proporcionar-lhes um trânsito mais seguro. O problema exposto consiste em descrever a elaboração de um método desenvolvido na disciplina de Educação para o Trânsito aos velhos da Universidade da Maturidade. Objetivo: Descrever o método de interação entre as gerações. Metodologia: Essa é uma pesquisa qualitativa que assumiu a forma de pesquisa ação. Resultados: Houve compreensão do respeito quanto ao limite do outro, e o exercício da cidadania. Conclusão: Acreditou que, com o desenvolvimento desse método diversos estudos podem ser elaborados a fim de sistematizar ações pedagógicas dos projetos intergeracionais, em especial nas universidades brasileiras.
“NOVAS” CONFIGURAÇÕES FAMILIARES NA CONTEMPORANEIDADE – UMA (RE) LEITURA DE MEUS DOIS PAIS, DE WALCYR CARRASCO (2010)
Authors: De Araujo Rubenilson Pereira
Published: June 2018

O presente artigo versa sobre as configurações familiares na contemporaneidade, sobretudo no que toca na possível transição entre heterossexualidade e homoafetividade em relação às orientações sexuais. O aporte teórico se centra nos estudos de gênero e se volta para os estudos literários com análise de um corpus na obra de literatura brasileira infantil, de Walcyr Carrasco denominada Meus dois pais (2010). A representação estética demonstra que a criança apta a compreender a diversidade sexual no tocante às (homo)conjugalidades, desde que o diálogo empreendido no processo de mediação da educação infantil.
GAME STUDIES ENCONTRAM JOGOS PARA SAÚDE: Uma entrevista com Espen Aarseth e Rune Nielsen
Authors: Andrade Luiz Adolfo
Published: June 2018

Os pesquisadores do Centro para Pesquisas em Jogos de Computador da IT – Universidade de Copenhagen, Espen Aarseth e Rune Nielsen, discutem nesta entrevista a relação entre jogos e cuidados com a saúde.
UM MAPA É UMA COISA IMPOSSÍVEL
Authors: Dal Pont Karina Rousseng
Published: June 2018

Ao contar sobre um dos processos de construção da minha tese de doutorado em educação, afirmo combates os modos predominantes como a cartografia é ensinada nas escolas. Seja pela reprodução como imagem estática dos fenômenos espaciais, ou como discurso que fixa a leitura do mundo, a cartografia escolar foi considerada um problema na pesquisa. Porém, mais do que definir outro meio didatizante de ensinar cartografia, esta tese escolhe pela criação de resistências na educação geográfica ao se aproximar da arte contemporânea. O que pode a arte contemporânea diante do que parece não se mover com a cartografia escolar? Acionei, pela invenção e abertura ao sensível, outras estéticas cartográficas a partir da imersão em oficinas de bordado, colagem e gravuras. Exercitei ao longo da tese o pensamento através da potência dessas ferramentas artísticas, com a educação geográfica como parte de um processo formativo emaranhado pela arte e pela educação. Ao afirmar o desejo de operar com as imagens cartográficas como expressão e sensação ao traçar sobre a cartografia escola possibilidades de exercitar a imaginação e outros modos de ler o mundo. Algo ainda indefinido, provisório, não localizável nos manuais de metodologias de ensino, que ainda possa estar de passagem.
TRAKINAGEM: cinema e educação na escola
Authors: Barbosa Cristiano
Published: June 2018

O projeto TraKinagem – Mostra de Cinema e Educação tem o objetivo de produzir e exibir filmes realizados em contextos escolares. Em oficinas com alunos e professores experimentamos um processo de filmagem-aprendizagem que explora de forma criativa os componentes da imagem na construção de filmes de curta duração. Nessas experimentações mobilizamos os conceitos de encontro, devir e cartografia de Gilles Deleuze e Félix Guattari, bem como de lugar da geógrafa inglesa Doreen Massey, buscamos cartografar os movimentos que dispararam novos modos de sentir, pensar e habitar um lugar-escola em construção com e através do cinema.
1895-1921 YILLARI ARASINDA BURDUR SANCAĞI’NDA MODERN TEMEL EĞİTİM KURUMLARI - MODERN BASIC EDUCATION INSTITUTIONS IN BURDUR SANJAK DURING THE OTTOMAN PERIOD
Authors: Çora Ersin
Published: June 2018

Osmanlı
Devleti’nde ilk modern temel eğitim kurumu 1873’de kuruldu. İptidai adı verilen
bu okulları II. Abdülhamit ülkenin her köşesine yaygınlaştırmak istedi. Temel eğitimdeki
modernleşme süreci Osmanlı Devleti’nin yıkılmasına kadar devam etti. Bu
makalenin amacı 1895-1921 yılları arasında temel eğitimdeki modernleşme
çabalarının Burdur’da yansımalarını ortaya koyarak, ülkede böyle bir dönüşüm
yaşanırken Burdur bundan ne kadar etkilenmiştir? Sorusuna cevap verebilmektir.

 Konya’ya bağlı bir sancak olan Burdur’da ilk
iptidai 1895’de açıldı. 1921 yılına kadar 50 iptidai kuruldu. Ancak 1914
Depremi ve I. Dünya Savaşı gibi olaylar iptidailerin bir kısmının kapanmasına neden
oldu. Burdur 1895-1921 arasında eğitim öğretim yapan hemen bütün iptidailer
öğretmen eksikliği, okul binalarının yetersizliği ve öğrenci devamsızlığı gibi
sorunlarla yüzleşmek zorunda kaldılar. Ayrıca iptidailerin açıldığı ilk
yıllarda halk eğitim konusunda bilinçsizdi. Tüm bu olumsuzluklara rağmen
Burdur’da iptidai öğretmenlerinin özverili çalışmaları ile temel eğitim
kurumlarının modernleşmesinde önemli bir adım atıldı. Halkın eğitime bakışı
açısı değiştiği gibi uygulanan müfredat programı milli bilincin oluşmasında
etkili oldu.
FABL TÜRÜNÜN 7. SINIF ÖĞRENCİLERİNİN GÖRSEL SANAT ÇALIŞMALARINA ETKİSİ - THE EFFECT OF FABLE GENRE ON VİSUAL ART STUDİES OF 7th CLASS STUDENTS
Authors: İNCEAĞAÇ Muhammet , YILMAZ Meliha
Published: June 2018

Görsel sanatlar derslerinde farklı kaynaklardan yararlanmak; derse karşı ilginin ve motivasyonun artırılması, öğrencilerin hayal gücünün harekete geçirilmesi, çalışmalarında imge zenginliği oluşturabilmesi, yaratıcı ürünler ortaya koyabilmesi gibi açılardan kuşkusuz önem arz etmektedir. Bu açıdan bakıldığında, yazılı ve sözlü edebiyat ürünleri; sanat eğitiminin amaçlarına ulaşmayı hedeflemiş her görsel sanatlar öğretmeninin başvurması gereken kaynaklardandır. Bu kapsamda edebiyat ürünleri, son derece zengin kaynaklar olarak karşımıza çıkarlar. Araştırmada, görsel sanatlar dersinde yararlanılacak kaynak olarak edebiyat ürünleri içerisinden ‘fabl’ türü tercih edilmiştir.Araştırmanın amacı; fabl türünün öğrencilerin görsel sanat çalışmalarına etkisi olup olmadığını ortaya koymaktır. Araştırma 2015-2016 eğitim öğretim yılında Kastamonu ilinde bulunan bir ortaokulun iki şubesinde öğrenim gören 7. sınıf öğrencileri ile sınırlıdır. Araştırma, 22 kontrol ve 22 deney grubu olmak üzere toplam 44 öğrenciye uygulanmıştır. Öğrenci resimleri, kuru boya tekniği kullanılarak gerçekleştirilmiştir. Bu çalışma, edebiyat ürünlerinden ‘Kurnaz tilki, kurt ve at’ adlı fabl ile sınırlıdır.Öğrenci çalışmaları; görsel sanatlar eğitimi uygulamalarında edebiyat ürünlerinin etkisini belirlemek amacıyla geliştirilmiş ve yayınlanmış olan dereceli puanlama anahtarı (rubrik) kullanılarak, dört alan uzmanı öğretim üyesi tarafından değerlendirilmiştir.Elde edilen veriler bilgisayar ortamına geçirilmiş ve ‘SPSS’ paket programları kullanılarak analiz edilmiştir. Görsel sanatlar eğitimi uygulamalarında fabl türünün etkisi Mann Whitney U-Testi sonuçlarına göre incelenmiş olup, dereceli puanlama anahtarı içerisindeki tüm maddelerde kontrol ve deney grupları arasında anlamlı farklılık ortaya çıkmıştır. Kontrol ve deney grupları arasındaki tüm maddeler p<0,05 olarak görülmektedir.
Dose-Dependent Increase in Unconjugated Cinnamic Acid Concentration in Plasma Following Consumption of Polyphenol Rich Curry in the Polyspice Study
Authors: Haldar Sumanto , Lee Sze Han , Tan Jun Jie , Chia Siok Ching , Henry Christiani Jeyakumar , Chan Eric Chun Yong
Published: June 2018

Spices rich in polyphenols are metabolized to a convergent group of phenolic acids. We conducted a dose-exposure nutrikinetic study to investigate associations between mixed spices intake and plasma concentrations of selected, unconjugated phenolic acids. In a randomized crossover study, 20 Chinese males consumed a curry meal containing 0 g, 6 g, and 12 g of mixed spices. Postprandial blood was drawn up to 7 h at regular intervals and plasma phenolic acids were quantified via LC-MS/MS. Cinnamic acid (CNA, p < 0.0001) and phenylacetic acid (PAA, p < 0.0005) concentrations were significantly increased with mixed spices consumption, although none of the other measured phenolic acids differ significantly between treatments. CNA displayed a high dose-exposure association (R2 > 0.8, p < 0.0001). The adjusted mean AUC0-7 h for CNA during the 3 increasing doses were 8.4 ± 3.4, 376.1 ± 104.7 and 875.7 ± 291.9 nM·h respectively. Plasma CNA concentration may be used as a biomarker of spice intake.
Distinguishing Hemodynamics from Function in the Human LGN Using a Temporal Response Model
Authors: DeSimone Kevin , Schneider Keith A.
Published: June 2018

We developed a temporal population receptive field model to differentiate the functional and hemodynamic responses in the human LGN. The hemodynamic response of the human LGN is dominated by the richly vascularized hilum, a structure that serves as a point of entry for blood vessels entering the LGN and supplying the substrates of central vision.  The location of the hilum along the ventral surface of the LGN and the resulting gradient in the amplitude of the hemodynamic response across the extent of the LGN has made it difficult to segment the human LGN into its more interesting magnocellular and parvocellular regions that represent two distinct visual processing streams.  Here, we show that an intrinsic clustering of the LGN responses to a variety of visual input reveals the hilum, and further that this clustering is dominated by the amplitude of the hemodynamic response. We introduce a temporal population receptive field model that includes both a sustained and transient temporal impulse response.  When we account for the hemodynamic amplitude, we demonstrate that this temporal response model is able to functionally segregate the residual responses according to their temporal properties.
A Holistic Theoretical Sustainability Assessment Model for Electricity Generating Sources
Authors: Mulongo Ndala Yves , Aigbavboa Cliton
Published: June 2018

In response to ever-increasing concerns regarding ecological degradation and societal impact, numerous stakeholders such as non-governmental organisations, government officials, end-users, the mass media, and community activists have compelled business organizations, particularly multi-national companies to lessen harmful greenhouse gases emissions associated with their production activities. Energy sector is one of the biggest harmful greenhouse gases emission producer, hence, decision-makers within the energy sector are forced to promote and build environmental friendly and sustainable power generation plants. To this end, the concept of sustainability in the electricity sector has attracted so much attention from academics and industrial practitioners over the last three decades. Albeit, an important number of sustainability assessment frameworks for electricity generating technologies are found in the current literatures, three major drawbacks have emerged from those frameworks. Firstly, there is a lack of a holistic and comprehensive sustainability assessment framework for different power generation plants. Secondly, from economic aspect, the most used model (Levelised Cost of Electricity) to measure the cost performance of various electricity generating technologies is biased and is not inclusive enough, because, it only considers the capital, Operations and Maintenance, and fuel costs. Hence, snubbing crucial elements to business decision. Lastly, in the current literature, there is no a single sustainability assessment model that considers all the phases of electrical energy’s lifecycle. Considering these flaws, the novelty of this study is the development of a new, holistic theoretical sustainability assessment framework for power generation plants. The developed theoretical model includes 19 impact categories, 52 potential indictors, and 10 end points environmental, economic, and social aspects.
From Experimental Procedure to Clinical Practice: How Much Evidence Do We Need in Uterine Transplantation?
Authors: Gainotti Sabina , Petrini Carlo
Published: June 2018

Background: Absolute uterine factor infertility (AUFI) is a kind of infertility that is completely attributable to uterine absence (surgical or congenital for women with Mayer-Rokitansky-Küster-Hauser syndrome: MRKH) or anatomic or functional abnormality that prevents embryo implantation or completion of pregnancy to term. Until recently, the only viable option to parenthood for couples with AUFI were adoption or surrogacy. Since a first attempt of uterus transplant (UTx) in 2000, nine babies were born from women with a transplanted uterus from 2014, eight of which in Sweden, and one in the United States. These promising results are raising immense hopes for the women with AUFI and there is optimism about the possibility for UTx to become part of clinical care even though, besides encouraging results, the procedure has also resulted in increased risks and harms for both the donors and recipients and increased risks of premature birth for the fetus. At present UTx is still considered as experimental and requiring more research and safety assessment before becoming a therapeutic option for AUFI. The transition from experimental procedure to therapeutic care would result in less strict ethical scrutiny for UTx and in the possibility for patients to get reimbursement for the procedure by the relevant healthcare insurance or public healthcare providers. In turn, an increase in the number of UTx performed yearly by specialized surgical teams would result in a general improvement of the “field strength”. However, at present it is difficult to establish the amount of evidence that we need in order to consider UTx as no longer experimental but routine clinical practice. The literature on UTx provides recommendations on the different outcomes that should be monitored in this experimental phase but no study is anticipating the number of subjects that should be followed and for how long. Conclusion: As for other transplants that have become routine practice, like renal transplant and heart transplant, it is likely that the decision on “routine practice readiness” will result from available cumulated evidences, from expert capacity to find a consensus on best practices and on political considerations as well, including pressures form patients and patient groups.
VALD: The Meeting Point of Data Producers and Data Users
Authors: Ryabchikova Tatiana , Pakhomov Yury , Piskunov Nikolai
Published: June 2018

Vienna Atomic Line Database (VALD) contains data on atomic and molecular energy levels and parameters of spectral lines required for stellar spectra analysis. Hundreds of millions lines for fine spectral synthesis and for opacity calculations are collected in present version of VALD (VALD3). Critical evaluation of the data and the diversity of extraction tools support high popularity of VALD among users. The data model of VALD3 incorporates obligatory links to the bibliography making our database more attractive as publishing platform for data producers. The VALD data quality and completeness are constantly improving allowing better reproduction of stellar spectra. To illustrate continuous evolution of the data content we present a comparative analysis of the recent experimental and theoretical atomic data for Fe-group elements, which will be included in the next VALD release. This release will also include a possibility for extracting the line data with full isotopic and hyperfine structures.
Multi-Scale Computational Simulation of Amorphous Silicates. Structural, Dielectric and Vibrational Spectroscopic Properties
Authors: Martínez-González José Ángel , Navarro-Ruiz Javier , Rimola Albert
Published: June 2018

Silicates are among the most abundant and important inorganic materials, not only in the Earth’s crust but also in the interstellar medium in the form of micro-/nano-particles or embedded in the matrices of comets, meteorites and other asteroidal bodies. Although the crystalline phases of silicates are indeed present in Nature, amorphous forms are also highly abundant. Here we report a theoretical investigation of the structural, dielectric and vibrational properties of the amorphous bulk for forsterite (Mg2SiO4) as a silicate test case by a combined approach of classical molecular dynamics (MD) simulations for structure evolution, and periodic quantum mechanical DFT calculations for electronic structure analysis. Using classical MD based on an empirical partial charge rigid ionic model within a melt-quenching scheme at different temperatures performed with the GULP 4.0 code amorphous bulk structures for Mg2SiO4 were generated using as initial guess the crystalline phase. This has been done for bulks with three different unit cell sizes adopting a super-cell approach; i.e., 1×1×2, 2×1×2 and 2×2×2. The radial distribution functions indicated a good degree of amorphisation of the structures. Periodic B3LYP-geometry optimizations performed with the CRYSTAL14 code on the generated amorphous systems were used to analyze their structure, to calculate their high frequency dielectric constants (ε∞), and to simulate the IR, Raman and reflectance spectra, which were compared with the experimental and theoretical crystalline Mg2SiO4. The most significant changes of the physico-chemical properties of the amorphous systems compared to the crystalline ones are presented and discussed (e.g., larger deviations in the bond distances and angles, broadening of the IR bands, etc.), which are consistent with their disordered nature. It is also shown that by increasing the unit cell size the bulk structures present larger degree of amorphisation.
Comparison of ecosystem services from mixed against monospecific forests in the Southwest Germany: A survey on public perception
Authors: Almeida Iulia , Rösch Christine , Saha Somidh
Published: June 2018

Scientific studies had shown that mixed forests of silver fir (Abies alba Mill.) and European beech (Fagus sylvatica L.) provide higher ecosystem services than monospecific forests. Mixed forests are known for their high resilience to climate change impacts and superior biodiversity compared to monospecific forests. In many countries, promotion of mixed forests in forest management is becoming a government policy since they can contribute to fulfill the Sustainable Development Goals set by the United Nation, respectively Goal 13 and 15. However, not much is known about public perceptions on mixed forests compared to monoculture forests. Our study on ecosystem services provided by mixed and monospecific forests in southwest Germany fill this gap. Based on a survey with 520 valid responses we analyzed people’s perception on 18 different supporting, cultural, regulating and provisioning ecosystem services measured by Likert scale. Stepwise regression analyses show relations between social profiles (gender, age, education, profession) and preferences on respondents’ perceptions. Our findings show that people perceive that mixed forests provide better cultural, regulating and supporting ecosystem services than monospecific forests of fir and beech whereas provisioning services were perceived as being equally or better provided by monospecific forests. Significant effects towards a positive perception on ecosystem services provided by mixed forests were mainly influenced by the perceived abundance of old trees, feeling of pleasantness in mixed forests, age, profession, and education. Our findings indicate that there is a high public support for the promotion of silver fir and beech mixed forests in Southwest Germany.
Intraocular Pressure Reduction in a Pigmentary Glaucoma Model by Goniotome Ab Interno Trabeculectomy
Authors: Wang Chao , Dang Yalong , Shah Priyal , Esfandiari Hamed , Hong Ying , Loewen Ralitsa , Waxman Susannah , Atta Sarah , Xia Xiaobo , Loewen Nils A.
Published: June 2018

Purpose: To investigate whether microsurgical excision of trabecular meshwork (TM) in an ex vivo pigmentary glaucoma model can normalize the hypertensive phenotype. Methods: Eight eyes of a porcine pigmentary glaucoma model underwent 90° of microsurgical TM excision with an aspirating dual-blade (Goniotome (G)). 24 hours later, an additional 90° of TM were removed. Anterior segments with sham surgeries served as the control (C). Outflow facility and intraocular pressure (IOP) were analyzed. Histology with hematoxylin and eosin (H&E) was obtained. Results: After the first 90° TM excision, IOP was significantly lower in G (10.23±2.39 mmHg, n=7) than C (20.04±1.97mmHg, n=8, P<0.01). Outflow facility in G (0.38±0.07 µl/min/mmHg) was higher than C (0.16±0.02 µl/min/mmHg, P<0.01). After the second 90° TM excision, IOP in G (6.46±0.81 mmHg, n=7) was significantly lower than C (20.25±1.66 mmHg, n=8, P<0.001), while the outflow facility in G (0.50±0.05 µl/min/mmHg, n=7) was higher than C (0.16±0.01 µl/min/mmHg, n=8, P<0.001). Compared to the first excision, excision of an additional 90° did not change of IOP (P=0.20) or outflow facility (P=0.17) further. Conclusion: Excision of 90° of TM in a pigmentary glaucoma model using an aspirating dual-blade decreased IOP and increased outflow facility. Translational Relevance: Microsurgical TM excision over 90° can effectively restore outflow in pigmentary glaucoma.
Inequalities of Hermite-Hadamard Type for Composite h-Convex Functions
Authors: Dragomir Silvestru Sever
Published: June 2018

In this paper we obtain some inequalities of Hermite-Hadamard type for composite convex functions. Applications for AG, AH-h-convex functions, GA, GG, GH-h-convex functions and HA, HG, HH-h-convex function are given.
Comparison of Hupresin® to Procainamide-Sepharose for Purification of Butyrylcholinesterase and Acetylcholinesterase
Authors: Lockridge Oksana , David Emilie , Schopfer Lawrence M. , Masson Patrick , Brazzolotto Xavier , Nachon Florian
Published: June 2018

Affinity chromatography on procainamide-Sepharose has been an important step in the purification of butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) since its introduction in 1978. The procainamide affinity gel has limitations. In the present report a new affinity gel called Hupresin® was evaluated for its ability to purify truncated, partly-deglycosylated human butyrylcholinesterase (rHuBChE) expressed in a stably transfected CHO cell line. We present a detailed example of the purification of rHuBChE secreted into 3940 mL of serum-free culture medium. The starting material contained 13,163 units of BChE activity (20.9 mg). rHuBChE was purified to homogeneity in a single step by passage over 82 mL of Hupresin® and elution with 0.1 M tetramethylammonium bromide in 20 mM TrisCl pH 7.5. The fraction with the highest specific activity of 630 units/mg contained 11 mg of BChE. Hupresin® is superior to procainamide-Sepharose for purification of BChE, but is not suitable for purifying native AChE because Hupresin® binds AChE so tightly that AChE is desorbed with denaturing solvents such as 50% acetonitrile or 1% trifluoroacetic acid. Procainamide-Sepharose will continue to be useful for purification of AChE.
EFEK SENTRA PEMOTONGAN AYAM TERHADAP KESEHATAN LINGKUNGAN MASYARAKAT PEMUKIMAN
Authors: Apriyanti Eka
Published: June 2018

Penelitian ini bertujuan untuk mengkaji praktik sanitasi rumah potong ayam. Hal ini muncul berdasarkan pengakuan bahwa tempat pemotongan ayam yang berada di tengah pemukiman warga terkesan kurang memperhatikan pembuangan limbahnya, sehingga memunculkan kekhawatiran warga terhadap kesehatan lingkungan masyarakat pemukiman. Survei untuk penelitian ini menggunakan kuesioner dan observasi lapangan. Sebanyak 31 unit usaha pemotongan ayam teridentifikasi di daerah penelitian dimana 80% dipilih secara acak.

Temuan menunjukkan bahwa pengelolaan limbah padat pada sentra usaha pemotongan ayam tergolong cukup baik yaitu: telah menyediakan wadah penampungan limbah, letak wadah di luar bangunan, berupaya mengurangi bau kotoran ayam, tersedia TPS (kontainer) dan pengangkutan limbah oleh petugas kebersihan, namun untuk pengelolaan limbah cair  tergolong sangat buruk yaitu: belum tersedia sarana pengolahan air limbah, tidak ada saluran khusus untuk limbah cair dan sebagian besar belum melakukan  penyaringan air limbah sebelum dialirkan ke saluran pembuangan sehingga menimbulkan bau busuk. Hasil uji lab BOD dan COD limbah cair dari tempat pemotongan juga telah melampaui baku mutu lingkungan yakni sebesar 3204,7 mg/L dan nilai COD sebesar 5969,6 mg/L.

Efek dari kegiatan pemotongan ayam terhadap kesehatan mayarakat pemukiman berdasarkan data yang diperoleh dari Puskesmas terdekat diketahui ada beberapa jenis penyakit yang diderita warga diakibatkan oleh kebersihan  lingkungan yang tidak memadai, seperti penyakit saluran pernafasan atas, diare, cacingan, penyakit kulit dan penyakit lainnya. Namun demikian untuk memastikan hal tersebut diperlukan kajian/penelitian yang lebih mendalam. Studi ini merekomendasikan kepada pemerintah Kota untuk melakukan pemantauan secara periodik terhadap operasi pemotongan hewan, termasuk sentra pemotongan ayam, penegakan hukum dan  peraturan sanitasi lingkungan di rumah pemotongan serta pendidikan lingkungan untuk para pengelola rumah pemotongan hewan dan penduduk.
REFLEXIONES CRÍTICAS SOBRE LAS ACTUACIONES AUTONÓMICAS DE INTERÉS PÚBLICO CON FINES TURÍSTICOS O TURÍSTICO-RESIDENCIALES
Authors: MELLADO RUIZ LORENZO
Published: June 2018

Los proyectos y actuaciones de interés regional son, en la actualidad, un instrumento territorial sometido a discusión y cuestionamiento. Entre otros fines, pueden legitimar la ordenación singularizada y la ejecución directa de actuaciones turísticas, en algunos casos con edificaciones residenciales aparejadas. El objetivo del presente trabajo es analizar críticamente estos instrumentos, desde el propio cuestionamiento de la suficiencia de la declaración de “interés general” para llevar a cabo estas actuaciones con posible merma de la autonomía local. Se sigue así una metodología crítica de análisis. Se parte de un estudio general de sus características para acabar analizando la regulación específica en la Comunidad Autónoma de Andalucía. La conjunción entre los nuevos paradigmas del turismo y la ordenación territorial y urbanística sostenible conducen a seguir cuestionando estas actuaciones, desde su necesaria racionalización y su reconducción hacia modelos de ocupación del espacio coherentes, estratégicos y ambientalmente sostenibles.
EL PRINCIPIO DE SUBSIDIARIEDAD EN LA LEGISLACION TURISTICA DE URUGUAY
Authors: FERREIRA ARIZAGA HUGO
Published: June 2018

En este capítulo proponemos analizar el principio de subsidiariedad en las actividades turísticas, sus antecedentes, fundamentación y, en especial, las características que presenta en el Derecho positivo uruguayo. La metodología utilizada es jurídica, mediante el relevamiento y análisis del Derecho comparado, normas constitucionales, legales y reglamentarias, así como también de la doctrina en la materia.
The promotion and inhibition of chromium and kinetic analysis on the growth of Platymonas Helgolandica
Authors: Bai Lijing , Li Zhaosong
Published: June 2018

In this work, Platymonas helgolandica was used as an experimental material to study the effect of chromium on it. Under the experimental ecological condition, the concentrations of Cr (VI) were set as 0, 0.05, 0.1, 1, and 10 mg/L. Every concentration designed with three parallel groups. The ecotoxicology method was used to investigate the impact of Cr (VI) on P. helgolandica, and (EC50) was calculated by the method of linear interpolation. The results showed the growth of P. helgolandica had a more obvious “Hormesis” when chromium was 0.05 mg/L. However, with Cr (VI) increased, the inhibition on P. helgolandica was increasing, and the cell density of P. helgolandica decreased. The EC50 achieved at 24 h, 48 h, and 72 h revealed that the relative growth rate had a downward trend over time. The remodified Logistic model, the modified Gompertz model, and the Logistic model were suitable to describe cell density in an operating cycle and were beneficial to explore the growth of P. helgolandica.
Dimensioning of vortex storm overflows
Authors: Mielczarek Szymon , Sawicki Jerzy M.
Published: June 2018

Vortex storm overflow is an interesting and useful technical solution, especially important in storm and combined sewage systems. However, there are no methods of this device dimensioning, which would be mathematically simple and properly precise physically. Such a method has been proposed in this paper, on the basis of investigations performed for the vortex separators and vortex flow controls. The essence of this method relies on the kinematic model of the velocity field and energy balance of the inflowing stream and dissipation. The procedure enables specialists to calculate the rise of the liquid free surface caused by the inlet stream energy and the hydraulic resistance of the bottom outlet. These mathematical relations are completed by two formulae: for the bottom ‘morning glory’ sink and for the upper overflow. The model has been positively verified during the laboratory measurements, so can be used during the technical dimensioning of the vortex storm overflows.
Образ мигранта в отечественных СМИ: особенности ценностно-смыслового восприятия в молодежной среде
Authors: Абакумова Ирина Владимировна , Гришина Анастасия Васильевна
Published: June 2018

This article underlines the particular role of the mass media as the important compound of the civil society in the conditions of the modern information society. The mass media play a crucial role in building subjective picture of the surrounding world of the young generation, particularly, social reality in its different aspects; it means they influence the whole world outlook. Frequently, the world outlook is greatly transformed and distorted under Mass media impact, it leads to the transformation within value and context spheres of different social groups and, especially, of the young people.
Исследование коммуникативной компетентности специалиста сферы социально-культурного сервиса
Authors: Терёхин Вячеслав Александрович , Евецкая Светлана Владимировна
Published: June 2018

The essence and concept of «communicative competence» is revealed in the article, the substructures of which are as follows: tolerance and interpersonal communicative experience, conflictology competence. Results of empirical research of communicative competence and its formation in the course of vocational training are represented.
Особенности влияния на молодёжную аудиторию материалов экстремистской направленности
Authors: Оселков Александр Александрович
Published: June 2018

In the article it is considered the problem of revealing of the psychological influence of materials of extremist orientation on youth audience; there are specified reasons of influence, channels of its realization. There are cited the experimental research data on revealing of the dynamics of emotional condition, relation and aggression at interaction with materials of extremist orientation, spent on 398 respondents.
Управление самостоятельной работой студентов технического вуза
Authors: Ефименко Светлана Владимировна
Published: June 2018

The article contains the results of psycho-pedagogical research on the independent work of technical college undergraduates. The main purpose of the research was to identify the tools for guiding the above mentioned type of students’ work and to describe it in relation to the psychological abilities of three categories of students (“widely subject-oriented”, “narrowly subject-oriented”, “subject-unoriented”) and the peculiarities of foreign language communicative teaching activity in a technical college.
Особенности субъективного благополучия субъектов зависти и соперничества
Authors: Бескова Татьяна Викторовна , Шамионов Раиль Мунирович
Published: June 2018

In the article there are analyzed features of interrelations of subjective well-being with envious relation of personality and its disposition to a rivalry strategy. There are revealed essential distinctions in considered interrelations: the tendency to rivalry is interconnected with general satisfaction in the basic spheres of the subject’s life activity on cognitive level; disposition to envy, on the contrary, correlates with dissatisfaction in cognitive and emotional levels. There are revealed basic strategies of superiority leveling, determined by negative result of social comparison in correlation with considered phenomena of envy and rivalry. There are revealed features of subjective well-being in groups with various strategies of leveling of superiority of the other in significant spheres.
Монетарное поведение субъектов с бесконфликтным ценностно-смысловым отношением к деньгам
Authors: Письменова Анастасия Александровна
Published: June 2018

In article tsennostno-semantic relations of the person to money are defined, typesfrictionless and components (motivational, когнитивный, emotional, конативный) tsennostno-semantic relations to money are considered. Definition of monetary behavior, its kinds (expenditure, accumulation and reception of money) is made. Characteristics of monetary behavior are offered: spatial, time, impulsiveness/rationality. Results of empirical research of features of monetary behavior of respondents with the frictionless tsennostno-semantic relation to money are resulted.
Особенности локализации внутри- и межполушарных когерентных связей у юношей и девушек с разными психологическими, психофизиологическими особенностями и уровнем успеваемости
Authors: Саакян Оксана Сааковна
Published: June 2018

This article describes the analysis of specific spatial-temporal organization of EEG in solving creative problems of various kinds of respondents with different levels of academic achievement and certain individual characteristics.
Аутопсихологическая компетентность как субъективно-акмеологическая детерминанта эффективности профессиональной деятельности менеджера
Authors: Астапенко Евгения Викторовна
Published: June 2018

In the article it is considered the complex model of auto-psychological competence of managers of different degree of efficiency. There are presented the results of empirical research, manifestations of auto-psychological competence in determination of efficiency of professional work of managers. There are given psychological portraits of managers showing different degree of efficiency.
Содержание компонентов и личностные детерминанты карьерного, матримониального планов и плана личностного роста студентов-выпускников
Authors: Астафьева Инна Николаевна
Published: June 2018

Given article is devoted revealing of the maintenance of components and personal a determinant of the life plans presented by an independent parity of career, matrimonial plans and the plan of personal growth of students-graduates in connection with their sexual differentiation. Substantial distinctions in leading motives, the purposes and means of a motivation-organizational component of life plans of men and women, features of an emotionally-estimated component, distinctions in subjects of plans at men and at women, distinctions in the personal features causing autonomy of female and man's variants of life plans are considered.
Коммуникативная компетентность педагога как фактор личностного развития ребенка с нарушением речи
Authors: Жизнева Наталья Владимировна
Published: June 2018

Communicative competence of the teacher is considered as the significant factor of personal development of the child with speech infringements. It is shown that modelling of the positive communicative environment renders фасилицирующее influence on development emotional and когнитивной spheres. The results of empirical research characterising features of influence of communicative competence of the teacher on development of the child with infringements of speech are resulted.
Особенности и проблемы изучения субъективного благополучия в современных психологических исследованиях
Authors: Елисеева Ольга Александровна
Published: June 2018

In the article there are resulted some problems connected with methodological aspects of research of a phenomenon of subjective well-being. The analysis of native and foreign researches has allowed to reveal that to the most widespread they concern the complexities at attempt of separation of subjective well-being from close concepts, the restrictions arising at a choice of diagnostic toolkit, necessity of account of social and cultural context at the research construction, some restrictions at the subjective well-being concept’s application to children and teenagers.
Учебная адаптация студентов к балльно-рейтинговой системе: новое понимание контроля знаний в учебном процессе
Authors: Куденцова Светлана Николаевна
Published: June 2018

New requirements towards the organization of the educational process at high school institution and especially towards knowledge control in the educational process, generates a number of psycho-pedagogical problems. This credit-rating system has obvious advantages, however its introduction into the educational process is going with difficulties. From teachers and students’ side there is misunderstanding of the system and negative attitudes towards it. The causes are hidden in the incorrect organization and control of the students’ success, which leads to their educational maladjustment. It is necessary to elaborate a range of the psycho-didactic recommendations for the successful realization of this system of the control in the real practice of the educational process at high school.
Педагогические проекции инструментализма в современной школе ФРГ
Authors: Федотова Ольга Дмитриевна , Дубовер Денис Анатольевич , Парастатова Виктория Викторовна
Published: June 2018

The article is devoted a problem of concretization of the instrumentalism philosophy in the education sphere. There are analyzed pedagogical projections of educational strategies “learning by doing”, “learning by going”, “learning by feeling”. It is shown their qualitative originality and difference from the instrumentalism pedagogics initial concept. Forms of realization of these concepts in the school practice of FRG are established and it is found out a deficiency in use of these constructs, connected with insufficient development of the gnoseological problematics in the didactics’ sphere.
Развитие креативных способностей обучающихся на основе инновационных технологий обучения иностранному языку
Authors: Колесина Карина Юрьевна , Малашихина Виктория Владимировна
Published: June 2018

The article describes the opportunities to develop students creative abilities by foreign language means on the basis of communicative and metaproject educational technologies in the course of working at metaprojects. Each metaproject creates the conditions for students creative abilities development.
Влияние экономико-психологических характеристик предпринимателя на стратегии оплаты труда в малом бизнесе
Authors: Кожевникова Ольга Анатольевна
Published: June 2018

The article reviews the results of an empirical study the effect of economic and psychological characteristics of personality Entrepreneurs (subjective scale of well-being, economic claims, subjective economic status, monetary attitudes) on the strategy op-armor work in small businesses: criteria for evaluating pay competitive pay labor in the foreign market, the structure of the internal market wage.
Особенности субъективных причин, затрудняющих конструктивное разрешение конфликта, у сотрудников с различным восприятием организационной культуры
Authors: Есипова Марина Евгеньевна
Published: June 2018

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Естественно-системные основания строения психики
Authors: Беломестнова Нина Васильевна
Published: June 2018

In the article it is considered a model of the psychics organization in evolutional-biological foundations. It is proved the necessity of construction of the natural psychics model, instead of the artificial one. In direct communication with such model there is also a problem of the mental phenomena classification. For the argument it is used the material of neuropsychology, psychophysiology, development psychology, pathopsychology, the physiology of sensory systems, activity physiology etc. It is underlined the methodological value of the natural psychics model’s generation.
Ценностно-смысловые барьеры педагогов-руководителей в процессе повышения квалификации: проблема интерпретации и типологии
Authors: Алимова Елена Евгеньевна
Published: June 2018

Training at the PDI should have the innovative, advancing character defining the content of preparation of the audience so that there would change the relation and positions of teachers and heads to professional work and school mission. Educational process at the PDI should be directed on creation of conditions when a subject position would be developed and reflective and creative abilities would be formed among the audience. a special part of the problem is preparation of the teachers-heads who are frequently not ready to operate in conformity with new professional requirements, as sociological and psychodiagnostic researches show. Many managers of the education system have value-sense barriers which impede modernization in real pedagogical practice.
Оценка готовности и способности проводников к корректному взаимодействию с пассажирами
Authors: Павлова Татьяна Анатольевна
Published: June 2018

A comparative analysis of key documents describing and regulating activity of conductors of passenger wagons in PLC “RZhD” and responsibilities, qualifications, and training programs of conductors of foreign railways (UK, France, Canada, Australia, USA) has showed that interaction with passengers as one of main duties of a conductor and his area of responsibility is not fixed nowhere clearly in OAO “RZD” in contradistinction to foreign railways. So nothing says that an interaction with passengers is a duty and responsibility of a conductor.
Частотно-пространственное распределение биоэлектрической активности коры мозга при музыкальной творческой деятельности у музыкантов
Authors: Денисова Ирина Анатольевна
Published: June 2018

In the work there are presented the results of the research of functional, spatial and structural correlates of musical creative activity with the view to reveal the cerebral mechanisms underlying creativity. There are revealed differences in the specificity of power spectral characteristics and the character of coherent correlations among the examinees at a creative problem decision process for different frequency ranges.
Process Analytical Technology for Crystallization of Active Pharmaceutical Ingredients
Authors: Malwade Chandrakant R. , Qu Haiyan
Published: June 2018

Background:

Pharmaceutical industry is witnessing increased pressure to introduce innovative and
efficient processes for manufacturing Active Pharmaceutical Ingredients (APIs) in order to be competitive as well
as to meet the stringent product quality requirements set by regulatory authorities. Crystallization with its ability
to engineer the final product to the desired qualities such as purity, polymorphic form, particle size and shape is
one of the most important steps involved in the manufacturing of APIs. Therefore, development of crystallization
processes with better understanding of process parameters and their impact on quality of APIs and subsequently
the drug products assume great significance for the pharmaceutical industry.

Methods:

This review paper focuses on the application of PAT tools, an integral part of Quality by Design (QbD)
approach, for better understanding, control, and design of crystallization processes in the manufacturing of APIs.

Results:

Firstly, various steps involved in the drug development process are introduced briefly with emphasis on
crystallization as one of the most important steps in manufacturing of drug products. Secondly, Critical Quality
Attributes (CQAs) of drug products, their dependence on material attributes of APIs and role of crystallization in
manipulating material attributes of APIs has been discussed. Finally, application of PAT tools such as advanced
process analyzers for continuous monitoring, chemometric methods for multivariate data analysis, and control
strategy for APIs crystallization processes has been reviewed along with some examples.

Conclusion:

Application of PAT in crystallization of APIs facilitates development of robust processes that works
within the design space to produce the drug products of consistent quality. Furthermore, it opens up the opportunities
for continuous improvement of the process by generating knowledge base of existing processes.
Design Graph Theoretical Analysis and In Silico Modeling of Dunaliella Bardawil Biomass Encapsulated N-Succinyl Chitosan Nanoparticles for Enhanced Anticancer Activity
Authors: Kunjiappan Selvaraj , Panneerselvam Theivendren , Somasundaram Balasubramanian , Sankaranarayanan Murugesan , Parasuraman Pavadai , Joshi Shrinivas D. , Arunachalam Sankarganesh , Murugan Indhumathy
Published: June 2018

Purpose: To investigate N-succinyl chitosan nanoparticles (NSC NPs) encapsulation with Dunaliella
bardawil (D. bardawil) biomass for high utilization enhanced effectiveness and least side effects for anticancer
activity.

Methods:

The potential bioactive compounds from D. bardawil biomass were encapsulated NSC NPs by
ionotropic gelation method and to characterize its molecular shape, particle size, stability and polydispersity
index using FTIR, XRD, SEM, TEM and Zetasize Nano analyzer. Signaling pathway analysis, molecular
docking study and in vitro anticancer screening were performed on chosen H-Ras P21, 721P and liver cancer cell
lines (HepG2), respectively.

Results:

The D. bardawil biomass majorly contains 6 bioactive compounds such as β-carotene, lutein,
zeaxanthin, phytoene, canthaxanthin, and phytofluene were identified by LC-MS. The D. bardawil biomass
encapsulated NSC NPs showed an average particle size of 80±5.6 nm in spherical shape, crystalline nature, zeta
potential of -32±2.7 mV and polydispersity index of 0.51±0.02. Interestingly, the identified target using graph
theoretical signaling pathway analysis and molecular docking study showed strong interaction of NSC NPs in
binding pockets of H-Ras P21 protooncogene. At 50μg/mL, NPs displayed 95.60% cytotoxicity in HepG2 cell
line. The apoptotic cell cycle analysis showed cell death for 24 h and 48 h representing 13.13% and 47.04%,
respectively.

Conclusion:

The highly cross-linked, biocompatible, biodegradable, nontoxic NSC NPs promising carrier for
delivery of bioactive molecules present in the D. bardawil biomass was found to be actively involved in
deregulation of cellular growth in targeted cancer cells. Thus active NPs serve as a novel nanodrug to enhance
the controlled; site specific drug delivery in the management of cancer.
Cytomegalovirus Replication Steps and the Actions of Antiviral Drugs
Authors: Abdullah Ashwaq Ahmed , Balakrishnan Krishnan Nair , Bala Jamilu Abubakar , Abdullah Faez Firdaus Jesse , Nazariah Zeenatul Allaudin , Abdullah Rasedee , Noordin Mohamed Mustapha , Mohd-Lila Mohd-Azmi
Published: June 2018

Human cytomegalovirus (HCMV) is a beta herpesvirus that inflicts an active infection in the
fetus and immunosuppressive patients. The virus encodes many proteins that work together with cellular
factors to achieve virus replication. In addition to vaccines, antiviral drugs can be deployed to manipulate
how the virus replicates and minimize its pathogenicity. The five antiviral drugs approved by the Food
and Drug Administration (FDA) have shown adverse reactions and the antiviral drug resistance were
reported. Hence, this warrants the need for urgent development of a novel antiviral drug. Detailed understanding
of the virus replication steps and how cellular signals interact with these steps will be key for
pharmacological developments of for anti HCMV drugs. This review summarized all the drugs that target
the virus proteins and cell signals that mediate CMV replication.