bluuebunny/crossref_metadata_2025 huggingface dataset:
Spectrum of HRCT findings in interstitial lung diseases and their correlation with mediastinal lymphadenopathy
Authors: Femina Hussain , Iqbal Showkathali , Binoj Varghese , Robert Ambooken P.
Published: March 2019

Background: Interstitial lung disease (ILD) represents a heterogeneous non-infectious group of acute and chronic diseases affecting the lung parenchyma. ILDs are usually associated with signiﬁcant morbidity and mortality, particularly when ﬁbrosis occurs. ILD is usually associated with mediastinal lymph node enlargement, the extent of lymph node enlargement may correlate to disease activity or progression of fibrosis. In the present study, authors have correlated the spectrum of high-resolution CT findings in ILDs with mediastinal lymph node enlargements.Methods: One hundred and four cases of ILDs confirmed by HRCT findings and pulmonary function tests were included in this study. HRCT was performed using a GE 128 SLICE CT OPTIMA 660 scanner, USA with 1.5 mm collimation at full inspiration. The findings were classified into three groups-fibrotic, ground glassing and nodular pattern. Authors assessed the presence, number and sites of enlarged lymph nodes (short axis ≥10 mm in diameter).Results: The largest subsets of patients were found in the 51-60 age groups. Fibrotic pattern was the most common pattern in this study (50%) followed by ground glassing (44%). Nodular pattern was the least predominant pattern (6%). Lymphadenopathy was seen in 84% of UIP and 63% cases of NSIP. P value was 0.049 which indicates a significant relation between lymphadenopathy and various ILDs. A strong relationship between lymphadenopathy and the predominant fibrotic pattern followed by ground glassing was observed.Conclusions: A significant association was established between lymphadenopathy and the type of ILD where fibrotic pattern had the maximum association.
A rare complication of spontaneous rupture of incisional hernia: case report
Authors: Thakkar Nimesh B. , Chauhan Abhesinh
Published: March 2019

Incisional hernia Complicates only 2%-10%. Spontaneous evisceration of content is very rare but whenever it occurs, it demands emergency surgery, to prevent further obstruction, strangulation of bowel and to cover its contents. The hernial contents can be covered primarily by mesh repair if the general condition of the patient and local condition of the operative site allows or can be covered by skin followed by delayed mesh repair. Authors report such rare case of spontaneous evisceration of omentum in 35 years old female patient who was known case of incisional hernia for 2 years. Neglect for early operative intervention or delay in seeking the treatment for an incisional hernia increases the risk of rupture.
Comparative study of open approach and laparoscopic surgery for emergent groin hernias
Authors: Kurumiya Yasuhiro , Mizuno Keisuke , Sekoguchi Ei , Sugawara Gen
Published: March 2019

Background: The utilization of laparoscopic surgery for groin hernias is rapidly increasing in Japan even though a consensus for the use of the laparoscopic over the open approaches to surgery for emergent cases has yet to be determined. Therefore, we retrospectively examined patient outcomes from both open and laparoscopic surgeries.Methods: Emergent surgery for a strangulated groin hernia was performed on 63 patients at our hospital from January 2013 to December 2017. All laparoscopic surgeries were performed using the transabdominal preperitoneal repair (TAPP) approach. The choice of whether to perform an open approach (open) or laparoscopic surgery with the TAPP approach was made by doctors who were familiar with both surgical techniques.Results: There were 49 patients in the open group and 14 patients in the TAPP group. The median operation time (min) was 78 in the open group and 127 in the TAPP group. The median intraoperative blood loss (ml) was 21.0 in the open group and 3.0 in the TAPP group. There were 12 patients (24.5%) in the open group and 1 patient (7.1%) in the TAPP group who had postoperative complications. Surgical site infection did not occur in the TAPP group.Conclusions: TAPP is a useful technique in emergent surgery for incarcerated hernias.
First rib fractures as indicators of serious intra and extra-thoracic injury in polytrauma and their impact on the morbidity and mortality
Authors: Al-Mourgi Majed
Published: March 2019

Background: First-rib fractures are relatively rare compared with fractures of other ribs because of the broad structure deeply placed and protected location of the first rib. A high amount of energy is needed to cause a first-rib fracture; violent trauma, such as that involving motor vehicle accident, is a frequent cause of these fractures, as well as other serious intra-thoracic, head, cervical spine, and intra-abdominal injuries. First-rib fractures have traditionally been considered indicators of increased injury severity and mortality in major trauma patients. The aim was to study the significance of first-rib fractures as indicators of serious intra-thoracic and extra-thoracic injury in polytrauma and their impact on the morbidity and mortality in a high-altitude area in Al-Taif, Saudi Arabia.Methods: This is a retrospective study conducted in King Abdul-Aziz Specialist Hospital (KASH), Taif City, KSA. Patients with chest injuries who presented to the emergency department and were admitted to the hospital between November 2013 and March 2016 were included in the study. Data regarding first-rib fracture were collected, and the relationship between first-rib injuries and associated intra-thoracic and extra-thoracic injuries was analyzed.Results: There was a high incidence of first-rib fracture (23.45%), and 35.8% were bilateral. The most common associated chest injury was a pulmonary contusion (58.5%), followed by pneumothorax (32.1%), hemopneumothorax (20.7%), and surgical emphysema (20.7%). The most common associated extra-thoracic injuries in our study were skeletal injuries (47.4%), cervical spine injuries (11.3%), and head trauma (24.5%).Conclusions: Fractures of the first-rib are associated with serious thoracic and extra-thoracic injuries; they are associated only with increased morbidity in patients with polytrauma and have no independent impact on mortality.
Predicting outcome of neuroblastoma using N-myc status and Trk-A expression
Authors: Chandrasekaran Sankkara Barathi , Vinayagamoorthy Gopinath
Published: March 2019

Background: Neuroblastoma is an embryonal cancer of the postganglionic sympathetic nervous system. It is the third most common pediatric cancer. The aim of the present study was to determine MYCN amplification and Trk-A expression in tissue samples of neuroblastoma cases and to correlate them with clinical status, stage and histopathology of the disease.Methods: This prospective study was conducted at the Institute of Child Health and hospital for children [ICH & HC], Egmore during the period from June 2011 to March 2012. Ten children of age between 8 months to 12 years diagnosed with neuroblastoma were included in the study. Tissue samples were collected from all patients and sent to evaluate histopathology to confirm the presence of neuroblastoma. Gene expression was studied using TaqMan quantitative RT-PCR. Immunohistochemistry of tissues samples were done to evaluate N-myc amplification and Trk A expression.Results: The most common presenting symptom was mass in the abdomen (60%) in the patients. In majority, stage 3 neuroblastoma was noticed in 5 (50%) cases. On histopathology, 2 (20%) cases were identified of ganglioneuro-blastoma, and 8 (80%) cases as neuroblastoma. N-myc was amplified in 3 cases (30%). No amplification was noted in all 3 cases (0%) of stage 1. None of the case in this study group showed Trk-A expression.Conclusions: N-myc amplification was well correlated with the stages of neuroblastoma. It should be considered to be as an important prognostic marker to select appropriate treatment in children with neuroblastomas.
A clinical study on the presentation and management of liver abscess in eastern Uttar Pradesh and evaluation of a low cost technique of percutaneous catheter drainage
Authors: Kumar Gupta Amit , Kumar Yogesh , Soni Annanya
Published: March 2019

Background: The objective of the study was to assess the outcome of various modalities of treatment and evaluation of a low cost technique of percutaneous catheter drainage of liver abscess.Methods: A prospective study of patients with liver abscess was conducted in a tertiary care centre over a period of one year. Since the cost of commercially available catheter (pig tail type) for image guided percutaneous drainage of liver abscess is quite high (approx Rs 800) and considering the fact that a considerable population in eastern Uttar Pradesh is poverty stricken, this study includes an evaluation of low cost technique of percutaneous drainage of liver abscess as a pilot project. In the present study K-90 was used as “low cost drainage” and compared with pig tail catheter drainage.Results: Total 34 patients with liver abscess were enrolled in the study. 31 cases were male and 3 cases were female. 34 cases were subjected to catheter drainage (pig tail catheter, K-90) yielding varying quantities of pus from 300 ml to 2200 ml, depending on the size of the abscess. 15 out of 34 patients underwent tube drainage (K-90) by our innovative trochar cannula system using 5 mm laparoscopic metal trochar.Conclusions: Although, compared to pig tail drainage, K-90 tube drainage is associated with more number of minor complication and prolonged hospital stay, however looking to the advantages and greatly reduced cost its use is probably justified.
Comparative study between excision with lay open and excision with primary closure in treatment of pilonidal sinus
Authors: Anandaravi B. N. , Viswanathan Aswath
Published: March 2019

Background: Pilonidal sinus is a common anorectal condition affecting young adults with various etiological factors. Various surgical methods have been described, but treatment failure and recurrence are frequent, causing considerable morbidity. This study was undertaken to study the different surgical methods in treatment of pilonidal sinus.Methods: This study was done between January 2017 and June 2018. 20 cases underwent excision with open healing and 10 cases underwent excision with primary closure. The surgeries for primary closure included Limberg flap, Karydakis technique and Z plasty. Patients were analyzed with respect to post operative complications, duration of hospital stay, duration of getting back to work and duration of wound healing.Results: Spectrum of clinical presentation included pain, discharge, sinus and swelling. No recurrences were observed in the present study. Wound infection occurred in only three cases. Duration of wound healing was found to be an average of 51.6 days in Excision with open healing method and 14.2 days in excision with primary closure method. The average length of hospital stay in excision and lay open group was 4.35 days and 5.4 days in the excision and primary closure group. The average duration to return to work was 34 days in excision and lay open group, while it was 8 days in excision and primary closure group.Conclusions: Excision with primary closure is a better modality than excision with lay open technique in treatment of pilonidal sinus.
A comparative study between onlay and sublay meshplasty in ventral hernias: a randomized controlled trial
Authors: Chitrambalam Tharun Ganapathy , Anguraj Preetham , Sundaraj Jeyakumar , Pethuraj Manimaran
Published: March 2019

Background: Ventral hernias are one of the most common surgical problems of the modern age. About 15-18% of all the surgical procedures performed around the world comprises of hernia repair. This study aims to compare the two common options of mesh placement in open ventral hernia repairs; over the anterior rectus sheath, the ‘Onlay meshplasty’ and in the retrorectus plane, the ‘Sublay meshplasty’.Methods: A prospective controlled study was done between March 2017 to August 2018 on 150 patients with ventral hernia randomizing patients into 2 groups. Group A (Onlay meshplasty) and Group B (Sublay meshplasty). Duration of surgery, post-operative pain, wound infection, duration of hospital stay and recurrences were analysed with 12 months follow up.Results: The mean duration of surgery in group A was 48.49±0.71 minutes and in group B was 72.84±0.72 minutes. Group B experienced significantly lesser pain when compared with group A. The mean asepsis score in group A was 3.60±1.09 and in group B was 0.47±0.30 with a p value of 0.006. Group A had significantly longer hospital stay (9.39 days) than group B (5.71 days). The recurrences in both the groups were statistically insignificant (Group A- 2 patients; Group B- 1 patient).Conclusions: Sublay meshplasty although requires longer time to perform, proves to be a better alternate in terms of post-operative pain, wound infection and hospital stay.
Clinicopathological study and management of liver abscess in tertiary care center
Authors: Ratnottar Jigar , Chauhan Harish , Modh Foram
Published: March 2019

Background: Liver abscess is a burning problem in tropical nations, with often lethal consequences and diagnostic/therapeutic challenges. We have determined etiopathology, clinical, radiological, and bacteriological characteristics of this condition and review its management strategies.Methods: During the period of the month from August 2017 to August 2018, a prospective study was performed involving 125 patients admitted to the in-patient ward of the Department of General Surgery of SMIMER Medical College their diagnosis was made on the basis of clinical features (such as right upper abdomen pain, and fever), laboratory investigations and radiological evidence of liver abscess.Results: Amoebic liver abscess was the most common (88%) type of liver abscess among the study groups. There was a strong correlation with the occurrence of liver abscesses and addiction to alcohol, history of diabetes mellitus and low socioeconomic status. The most common etiology of pyogenic liver abscess was Escherichia coli. Ultrasonography (USG) of the abdomen was accurate and cost-effective in diagnosis of liver abscesses. Percutaneous catheter drainage was the most effective method of treatment (with a 100% success rate).Conclusions: Most patients in our study had liver abscess of amoebic origin and had temporal relationship with diabetes, alcoholism, and staggering socioeconomic status. We suggest early recognition of clinical features and prompt abdominal USG as cost-effective means for treatment initiation and reducing complications.
Efficacy of cyanoacrylate glue in anal fistulas
Authors: Shivashanka Santhosh Chikkanayakanahalli , Nagaraja Nayaka Aruna Nayaka , Manangi Mallikarjuna , Rao Seshagiri , Masanashetty Srinivas Nanjangud
Published: March 2019

Background: Fistula in ano is a common problem. Surgical techniques such as fistulectomy, fistulotomy were associated with complications like excessive bleeding, infection, recurrence etc. The employment of cyano acrylate glue is one of the newer promising techniques. The aim of this study was to evaluate the efficacy of cyanoacrylate glue in the treatment of anal fistulas.Methods: Study was conducted on patients with fistula-in-ano admitted to various surgical units in hospitals attached to Bangalore Medical College and Research Institute from November 2016 to May 2018. A total of 30 patients fulfilling the criteria were included in the study. Under spinal anesthesia, patients were posted for the procedure. Post operatively the patients were examined every 2 weeks for the first 2 months, and then once every 3 months. If the fistula failed to heal with primary treatment at a 4-week interval, a second glue treatment was performed. Post-treatment the success of the procedure was assessed by the incidence of infection and recurrence.Results: Twenty two patients got healed with primary application with stoppage of any discharge from the fistulous track. Two patients required one more application, and one patient required fistulotomy. One patient developed complex fistulas and had to be treated with colostomy and fistulectomy. 4 patients developed purulent discharge after application of glue and were treated with IV antibiotics and healed completely.Conclusions: Cyanoacrylate glue can be offered as a sphincter sparing alternative to fistulectomy in patients with anal fistulas.
Role of digital photography in evaluation of gallbladder specimens following laparoscopic cholecystectomy for gallstone disease: a prospective observational study
Authors: . Vidyasagar , Pol Manjunath Maruti , Chumber Sunil , Singh Rathor Yashwant
Published: March 2019

Background: Digital photography helps in accurate documentation of macroscopic features of specimens and preventing inaccuracies in description of macroscopic features. Some studies recommend a digital color print be sent with each specimen to histopathology laboratory. The aim of the study was to assess the necessity of histopathological examination of resected specimen of gallbladder with no features suspicious of carcinoma gall bladder on clinicoradiological study.Methods: It is a prospective observational study conducted in the Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, between 2014 and 2016. Patients between 18 to 60 years of age with gall stone disease with no features suspicious of carcinoma gall bladder on clinicoradiological study were recruited in the study. Post-cholecystectomy gallbladder specimens were considered as subjects of study. Specimen were photographed and sent for histopathological examination. Macroscopic features on digital photography were compared with histopathological findings.Results: About, 39/100 (39%) gallbladder specimens showed abnormal findings on digital photography; 30/39 (77%) had ulcerations, 5/39 (13%) had polypoidal lesions and 4/39 (10%) had diffuse wall thickening. 1/39 (2.6%) specimens with abnormal finding on digital photography was found to be malignant on histopathological examination. The sensitivity, specificity, negative predictive value and positive predictive value of digital photography was 100%, 67.7%, 100% and 3.03% respectively.Conclusions: Digital photography can prove to be a good tool in documenting macroscopic features of gallbladder specimens. Digital photography is associated with high sensitivity and negative predictive value; however, larger sample size is required to establish its significant correlation.
Unusual presentation of pancreatic pseudocyst as a psoas abscess
Authors: Jain Vimal Kumar , Hadiyal Ashishkumar , Jolly Shalit
Published: March 2019

A chronic collection of pancreatic fluid (rich in amylase, lipase and enterokinase) surrounded by a nonepithelialized wall of granulation tissue and fibrosis is referred to as a pseudocyst. Though most frequent loacation is the lesser peritoneal sac, 20% are located at extra pancreatic sites like pleura, mediastinum, pelvis, spleen, liver and perinephric space. Rarely, it can be present as a psoas abscess and this type of presentation is common in middle aged men who are chronic alcoholic. Recent history of pancreatitis may be present. CECT whole abdomen is initial investigation of choice. Presence of high level of amylase and lipase in the aspirate from psoas abscess is confirmatory for the diagnosis.
Faecolith leading to acute exacerbation of chronic appendicitis: case report and review of literature
Authors: Kishore Anand , Jaiswal Anand Kumar
Published: March 2019

Acute appendicitis remains the most common acute condition often requiring surgical intervention. Obstruction of appendicular lumen by faecalith or lymphoid hyperplasia is the main cause of acute appendicitis. There is no possible way to prevent the development of acute appendicitis. The only way to reduce morbidity and mortality is by timely intervention and doing appendicectomy before perforation and gangrene of appendix occurs. We report a case of chronic appendicitis by a giant faecolith leading to chronic pain. This case is being reported is an example of how large an appendiceal faecalith can be.
TCP TIPS: Transport Protocol for Unreliable Networks with Latency-Sensitive Data
Authors: Sivov A. A.
Published: March 2019

The article describes TCP TIPS, the transport level protocol, which aim is to effi- ciently use the available bandwidth. This protocol implements the proactive methods for congestion avoidance. These methods allow TCP TIPS to yield the required amount of bandwidth to high-priority flows with realtime data and to use this amount, when it becomes available.
Oscillations in Arrays of Nonlinear Elements in the Scott Experiment
Authors: Bobok A. S. , Glyzin S. D.
Published: March 2019

Bifurcation analysis of dynamic system modeling the array of coupled ocillators in the experience of Scott are presented. The non-resonant cases are considered.
On the Hereditary Properties of Modular Nets
Authors: Bashkin V. A.
Published: March 2019

Hereditary graph properties are those that can be inherited from the graph to all its subgraphs (such as planarity). Modular nets of active resources is a (Petri nets)- powerful formalism with simple modular syntax. Boundedness and liveness are fundamental semantic properties for Petri net models. It is shown that boundedness and liveness, being not hereditary in general, are downward-hereditary (net-to-subnet) and upward-hereditary (subnet-to-net) for the particular types of AR-subnets. It is also shown that boundedness is downward-hereditary and unboundedness is upward-hereditary for arbitrary subnets after a specific module interface transformation (so-called R-normalization).
Video images compression and restoration methods based on optimal sampling
Authors:   State Research Institute of Aviation Systems, Drynkin V.N. , Nabokov S.A. ,   State Research Institute of Aviation Systems, Tsareva T.I. ,   State Research Institute of Aviation Systems
Published: March 2019

The study proposes video images compression and restoration methods based on multidimensional sampling theory that provide four-fold video compression and subsequent real-time restoration with loss levels below visually perceptible threshold. The proposed methods can be used separately or along with any other video compression techniques, thus providing additional quadruple compression.
Demonstration of resonant phenomena analogous to Autler-Townes splitting, electromagnetically induced transparency and Fano resonances in a deformed waveguide resonator
Authors:   Institute of Automation and Control Processes FEB RAS, Dyshlyuk A.V. ,   Far Eastern Federal University,   Vladivostok State University of Economics and Services
Published: March 2019

In this paper, we demonstrate resonant phenomena analogous to Autler-Townes splitting, electromagnetically induced transparency and Fano resonances in a resonator based on a single-mode optical waveguide with metallized end-faces. The phenomena are shown to result from strong coupling between the fundamental mode of the waveguide core and the cladding whispering gallery mode. The results obtained open new possibilities in the field of building functional photonic elements using cladding modes of bent waveguides and, in particular, fiber optic refractometers for bio- and chemosensing applications.
Design Sprint Methods for Developing Mobile Learning Application
Authors: Sumual H , Reimon Batmetan J , Kambey M
Published: March 2019

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Polymorphic locus rs652438 of the MMP12 gene is associated with the development of hypertension in women
Authors: Moskalenko M. I. , Ponomarenko I. V. , Polonikov A. V. , Churnosov M. I.
Published: March 2019

Objective.To study the association of polymorphic loci rs243865 MMP2, rs17577 MMP9, rs652438 MMP12 with the development of arterial hypertension (HTN) in women of the Central Chernozem Region of Russia.

Design and methods.A total of 584 women were examined: 375 HTN patients and 209 controls. Analysis of the polymorphic loci of metallоproteinases was performed using real-time polymerase-chain reaction (PСR). Statistical analysis was carried оut using software “STATISTICA for Windows 10.0”. The prediсtive value of the non-synоnymous single nucleotide polymorphism (SNP) wаs estimatеd using the Sorting Tolerant From Intоlerant software (http://sift.jcvi.org/). The regulatorу potential of polymоrphic loci was analyzеd in the HaplоReg software (v4.1) (http://archive.brоаdinstitute.оrg). The effect of SNP on gene expression was studied using thе data of the Genоtype-Tissue Expressiоn project (http://www.gtexportal.оrg/).

Results.We found an association of the locus rs652438 MMP12 with the occurrence of HTN in women. Polymorphic variant G (odds ratio (OR) = 1,86, 95 % confdence interval (CI) = 1,02–3,45, p = 0,04) and genotype GA (OR = 2,04, 95 % CI = 1,06–3,98, p = 0,03) of rs652438 are associated with the high risk of HTN development. The genotype AA rs652438 demonstrates a protective effect regarding the risk of HTN occurrence (OR = 0,50, 95% CI = 0,26–0,95, p = 0,03). We assume that the epigenetic effects of rs652438 MMP12 underlie the identifed associations. The locus rs652438 MMP12 is nsSNP and has a SIFT Score = 0,01. This polymоrphism is lоcated in histоnes regiоn marking prоmoters (H3K9 ас) and enhаncers (H3K4me1, H3K27 ас). The locus is in linkage disequilibrium (r 2 = 0,95) with SNP that affect the expression level of the MMP12 gene
Translating Peasant Resistance to Anti-Colonialism: the Ghadar Party in Punjab, 1914-1915
Authors: Tirmizey Kasim Ali
Published: March 2019

The Ghadar Party introduced a radical anti-colonial praxis to Punjab, British India, in the early 1910s. Much of the literature on the Ghadar Party situates the birth of the movement among Punjabi peasants along the Pacific coast of North America who returned to their homeland intent on waging an anti-colonial mutiny. Harish Puri (1993) locates the failure of the Ghadar Party in the impossibility of translating their migrant political consciousness among their co-patriots in Punjab. Further, he argues that their lack of organization skills led to their demise. I argue in this paper that the Ghadar Party's political organizing made attempts at translating anti-colonial ideology into Punjab. This was accomplished through translating extant forms of peasant resistance, such as banditry and mutiny, into the social and political context of 1910s Punjab. Further, the appearance of lack of organization really was a belief in organized spontaneity and an under-mediated notion of rebellion.The Ghadar Party introduced a radical anti-colonial praxis to Punjab, British India, in the early 1910s. Much of the literature on the Ghadar Party situates the birth of the movement among Punjabi peasants along the Pacific coast of North America who returned to their homeland intent on waging an anti-colonial mutiny. Harish Puri (1993) locates the failure of the Ghadar Party in the impossibility of translating their migrant political consciousness among their co-patriots in Punjab. Further, he argues that their lack of organization skills led to their demise. I argue in this paper that the Ghadar Party's political organizing made attempts at translating anti-colonial ideology into Punjab. This was accomplished through translating extant forms of peasant resistance, such as banditry and mutiny, into the social and political context of 1910s Punjab. Further, the appearance of lack of organization really was a belief in organized spontaneity and an under-mediated notion of rebellion.
Of subalterns and Sammi trees: echoes of Ghadar in the Punjabi literary movement
Authors: Kazmi Sara
Published: March 2019

This paper explores how Ghadar’s legacy is interpreted by the Punjabi literary movement in Punjab, Pakistan. Putting Ghadar’s poetry into conversation with the work of these contemporary activists sheds light on unexplored facets of both. It unveils how these writers and thespians invoke Ghadar to subvert the narrow discourse of “Punjabiyat” and ethno-nationalist identity, and allows us to appreciate the politics of language that underpinned Ghadar di Goonj. The intertwining of these histories of literary dissent raises key questions for debates around radical literature and progressive writing in South Asia, by highlighting the role of vernaculars in reading subaltern consciousness and native traditions of revolt.
POVEZANOST PERCEPCIJE SIGURNOSTI POSLA I ZADOVOLJSTVA ASPEKTIMA POSLA SA KONTRAPRODUKTIVNIM RADNIM PONAŠANJIMA
Authors: Strizović Ivana
Published: March 2019

Istraživanje je sprovedeno sa ciljem utvrđivanja organizacijskih faktora koji doprinose razvoju kontraproduktivnih radnih ponašanja. U skladu sa postavkama Teorije samodeterminacije, kao i na osnovu rezultata prethodnih istraživanja, pretpostavljeno je da će percepija veće nesigurnosti posla biti u pozitivnoj vezi sa kontraproduktivnim radnim ponašanjima. Takođe, ovim istraživanjem pretpostavljeno je da će zadovoljstvo poslom biti u negativnoj vezi sa kontraproduktivnim radnim ponašanjima, pri čemu će nezadovoljstvo kolegama i nadređenima biti najznačajnije determinante. U istraživanju je učestvovalo 233 zaposlenih, koji su se razlikovali u odnosu na sociodemografske varijable i tip zaposlenja. Rezultati su ukazali na to da postoji statistički značajna povezanost između zadovoljstva poslom i kontraproduktivnih radnih ponašanja, dok pretpostavka o postojanju značajne povezanosti između učestalosti ispoljavanja kontraproduktivnih radnih ponašanja i percepcije sigurnosti posla nije potvrđena. Iako dobijeni rezultati potvrđuju značaj organizacijskih činilaca u objašnjenju kontraproduktivnih radnih ponašanja, ti činioci objašnjavaju samo mali deo njihove varijanse, te bi buduća istraživanja trebalo da koriste interakcionistički pristup prema kojem se ispoljavanje kontraproduktivnih radnih ponašanja može najbolje predvideti ukoliko su nam poznate osobine ličnosti zaposlenih, kao i karakteristike organizacije.
THE COGNITIVE PROCESSING OF DERIVED NOUNS WITH AMBIGUOUS SUFFIXES: BEHAVIORAL AND EYEMOVEMENT STUDY
Authors: Gatarić Isidora
Published: March 2019

The primary aim of this research has been to investigate whether the suffix ambiguity affects the lexical processing of derived nouns in Serbian. Consequently, in the Experiment 1, the derived nouns were presented isolated to participants in the visual lexical decision task. Bearing in mind that the sentence context was important for the lexical processing, the Experiment 2 was designed as an eye-movement study with the sentences (with derived nouns from the Experiment 1) as stimuli. To the best of our knowledge, the similar experimental study was not performed before in the Serbian language, and therefore this study represents the first attempt to investigate this phenomenon in Serbian. An identical statistical analysis was used to analyze the data collected in both experiments, the Generalized Additive Mixed Models (GAMMs). The final results of all GAMMs analyses suggested that the suffixal ambiguity did not affect the lexical processing of derived nouns in Serbian, regardless of whether they were displayed isolated or in the sentence context. The observed results supported the a-morphous perspective in the morpho-lexical processing, as well as the distributed morphology insights from the theoretical linguistics.
The Effect of Assertiveness Psychoeducation Program on Increasing the Assertiveness of University Students
Authors: PARMAKSIZ İzzet
Published: March 2019

This study examined whether or not the
psychoeducation program, which was revised by field experts for university
students with low assertiveness level, increased participants’
assertiveness.  The study was designed
using pretest, posttest and follow-up test. In order to compare the effect of
the program, the study employed the experimental model in which a control group
was formed. The study group consisted of a total of 16 students who were
attending a university’s vocational school in Central Anatolia during the
academic year of 2017-2018. There were eight students in the experimental group,
and eight in the control group. The participants were selected on a volunteer
basis. Developed by Voltan-Acar and Öğretmen (2007) to measure the
assertiveness levels of university students, Voltan-Acar Assertiveness
Inventory was used to collect the study data. The difference between the
assertiveness levels of the participants in the experimental and control group
was examined.  Mann-Whitney U-test was
used for different groups to analyze the differences between groups. Wilcoxon
signed ranks test was employed to analyze the change within the same group. At
the end of the study, there was a significant increase in the assertiveness
levels of the participants in the psychoeducation program. This training will
contribute to theoretical and practical studies and to field experts in the
field of assertiveness and social skills acquisition. It will also encourage
future studies on assertiveness.
Cameos of Compassion: Exploring compassionate care using secondary analysis of digital patients’ stories
Authors: Dillane Bebhinn , Ezhova Ivanka , Ryan Sara , Tee Stephen , Rafferty Anne Marie
Published: March 2019

Patient stories have been identified as a powerful tool to improve quality of care. Healthtalk.org is a digital resource (specific health-related website) presenting patients’ experiences of illness and healthcare through trigger films, videos and articles. Data have been generated from narrative interviews conducted by experienced researchers, based at the Health Experiences Research Group (HERG), University of Oxford. Our project explored the potential use of secondary analysis of digital sources as a methodological innovation to develop as a tool for teaching compassion to nursing students. For that, a purposive sample of transcripts from the HERG archive were selected for secondary analysis. Patients expressed both positive and negative experiences of care. Positive themes included: continuity of care and attentiveness to the fundamentals of care. Negative themes were related to poor quality of care; ignoring patient and family needs; and not being available for patients and family when needed. We concluded that secondary analysis of narrative interviews provides a powerful resource for identifying positive and negative patient experiences for learning and teaching. These can be designed into a digital toolkit and used as a learning and teaching resource to develop staff and students’ reflexivity in relation to the values and leadership behaviours associated with compassionate care and positive practice.
Genetic background of Meniere’s disease
Authors: Szyfter Krzysztof , Gawęcki Wojciech , Szyfter Witold
Published: March 2019

Meniere’s disease (MD) as an inner ear disorder including such symptoms as recurrent vertigo attacks, tinnitus, fluctuating or progressive sensorineural hearing loss. Its relatively frequent familial incidence implicates a genetic background. An autosomal dominant inheritance was commonly observed with a few exceptions. It was established that Meniere’s disease is not a monogenic disorder. Instead a group of genes of genomic and mitochondrial genes was established as determinants of hearing loss. Another group of genes was associated with inner ear (vestibulum, labyrinth, endolymph) alterations followed by dizziness and tinnitus. Altogether, many studies suggest a multigenic interaction to predispose to develop Meniere’s disease.
The characteristic of dietary supplementation among elderly women
Authors: Wojciak Rafal Wojciech , Cisek-Woźniak Angelika , Tomczak Ewa
Published: March 2019

Aim. There is a growing awareness in Polish society, that a healthy lifestyle and proper nutrition have positively affected in old age. This effect influences the increasing consumption of dietary supplements to improve the health, however sometimes in an uncontrolled way. Taking above together the aim of this preliminary study was to assess the prevalence of the use of dietary supplements in elderly women.Material and Methods. The study was conducted on 95 elderly women aged 65 to 89 years. The participants were asked to complete a questionnaire about their physical activity as well as medicines and supplements intake.Results. Based on the questionnaire, it can be concluded that supplementation was common among the tested group. The most frequently seniors used preparations to assist the circulatory system and diet supplements. They also took this, supporting the work of the intestine, to assist urinary tract and the work of heart. The decision to start of supplementation was most often taken under the influence of television advertisements, pharmacy worker as well as from friends. There were statistically differences in presented results between studying populations according to their age. Conclusions. Important and essential is education of older people, concerning the appropriate use of dietary supplements, to make supplementation safe and distinct improvement in health.
Comparison of antibiotic resistance and virulence in vancomycin-susceptible and vancomycin-resistant Enterococcus faecium strains
Authors: Sieńko Anna , Czaban Sławomir , Ojdana Dominika , Majewski Piotr , Wieczorek Anna , Sacha Paweł , Tryniszewska Elżbieta Anna , Wieczorek Piotr
Published: March 2019

Aim. Today, infections caused by vancomycin-resistant Enterococcus faecium (VRE) are a major problem in the healthcare system. The aim of this study was to compare the antibiotic resistance and virulence traits between vancomycin-susceptible E. faecium (VSE) and VRE clinical isolates.Material and Methods. Studies were performed on 66 E. faecium (32 VRE and 34 VSE) strains. Susceptibility testing and identification were performed, and strains were examined for ß-lactamase, hemolysin and biofilm production. Isolates were tested for the presence of 5 van genes, 8 virulence genes and 6 aminoglycoside-modifying enzyme (AME) genes. Obtained amplicons were subjected to electrophoretical separation and DNA sequencing.Results. Among 32 VRE isolates, 28 were found to have the VanA phenotype, and 4 the VanB. The most frequent resistance and virulence profile among VRE strains was resistance to ampicillin, imipenem, gentamicin, streptomycin, teicoplanin, and vancomycin with enterococcal surface protein (esp), endocarditis antigen (efaA), collagen adhesin (acm), and hialuronidase (hyl) genes; among VSE: resistance to ampicillin, imipenem, gentamicin, streptomycin with esp, efaA, acm, and hyl genes. Conclusions. Our findings prove that both VRE and VSE strains were well equipped with virulence and resistance genes, although VRE strains were characterized by a greater variety and a higher number of these genes. However, statistical analysis revealed no significant differences between VSE and VRE strains (p > 0.05). Nevertheless, our results suggest that VRE strains may slowly acquire and incorporate resistance and virulence genes, due to their ability to survive in a hospital environment for a long time.
Minerals in the diet of adolescents aged 15
Authors: Waksmańska Wioletta , Woś Halina , Łukasik Renata , Bobiński Rafał , Pielesz Anna
Published: March 2019

BackgroundStudies which focus on the supply of minerals in the diet of adolescents show that the diet is deficient in such macroelements as calcium and magnesium and such microelements as copper, zinc, iodine and iron. Inadequate supply of minerals may increase the risk of development of diet related diseases at a mature age.MethodsThe questionnaire on the consumption of food products consumed every day for the period of 7 days was filled in by the person conducting the survey. The needs for minerals were defined individually for every child with reference to recommended dietary allowance.ResultsThe norm of daily sodium intake among 15-year-old adolescents was exceeded in all tested groups, however, in the group of boys sodium intake was at a higher level than in the group of girls. Potassium intake in the group of both girls and boys did not reach the recommended daily value, whereas the recommended daily consumption of manganese was exceeded twice. In all tested subjects, the ratio of calcium to phosphorus was very low. In the group of girls who are underweight, daily consumption of iron did not cover 50% of the demand.ConclusionsInadequate supply of minerals recorded in all tested 15-year old subjects, regardless of their BMI, may lead to developmental disorders and diet related diseases at a mature age.
Mass spectrometry analysis of redox forms of High-Mobility Group Box-1 Protein in cerebrospinal fluid: initial experience.
Authors: Światły Agata , Wąsik Norbert , Hajduk Joanna , Matuszewska Eliza , Dereziński Paweł , Sokół Bartosz , Jankowski Roman , Kokot Zenon , Matysiak Jan
Published: March 2019

Introduction. High-mobility group box 1 (HMGB1) is an alarmin with proinflammatory potential determined by redox status of the cysteines at position 23 and 45. It may also play a role as a biomarker in biological fluids. The aim of this study was the identification of different HMGB1 redox forms in cerebrospinal fluid (CSF) obtained from subarachnoid hemorrhage patients.

Material and Methods. 6 CSF samples were collected from aneurysmal subarachnoid haemorrhage patients. Commercially available HMGB1 isoforms served as a positive control. Immunoprecipitation and electrophoretic isolation of HMGB1 protein were performed, then both CSF and control were analyzed using mass spectrometry technique. To distinguish between fully reduced (thiol group at C23 and C45) and disulfide (disulfide bond connecting C23 and C45) HMGB1 forms, top-down sequencing of the spectra was performed.

Results. Top-down sequencing analysis allowed to distinguish between HMGB1 isoforms only in commercially available standard without preceding immunoprecipitation and electrophoresis. MALDI spectra differ i.e. on the fully reduced HMGB1 spectrum fragmentation occurs before and beyond C22, which is not present on the disulfide HMGB1 spectrum. Analysis of HMGB1 isolated from CSF obtained from subarachnoid hemorrhage patients gave no results.

Conclusions. Top-down sequencing enables to distinguish between redox forms of HMGB1. Electrophoresis and tryptic digestion cannot precede mass spectrometry analysis of redox forms of HMGB1 due to the reduction of disulfide bonds during these processes. Preferred method of isolation of HMGB1 for direct analysis using top-down sequencing mustn’t include protein digestion or degradation.
Force decay of intermaxillary orthodontic elastics: in vitro study
Authors: Kardach Hubert , Olszewska Aneta , Firlej Ewa , Bogdanowicz Agnieszka , Golusińska-Kardach Ewelina , Szponar-Żurowska Anna , Biedziak Barbara
Published: March 2019

Introduction. Orthodontic elastics are widely used in orthodontic treatment. It’s been proved that they have advantages such as low cost, ease of use, but also disadvantages, mainly force decay in time and increased entrapment of biofilm. Amount of the force is of extreme significance. This force can be altered by physical or chemical factors. Material and Methods. Latex elastics in 3 different diameters were selected for this study. Each elastic was stretched and placed on hooks that are at specified distances that equal 3 times the diameter of each elastic. The forces produced by stretching was measured using tension gauge and the measurement were taken at specific time intervals of 0h, 3h, 12h, 24h. The same process was repeated for elastics in dry and artificial environment. Results. Elastics in the dry environment showed progressive force decay cause by stretching over time. Just after 3 hours force decay between 6,07% and 8,75% was observed. The biggest loss of force between 13,61 — 16,13 % was measured after 24 hours. Compared to the dry environment, an even more significant force decay was observed in the artificial saliva. After first 3 hours force loss was between 4,99% — 9,22%. The biggest force decay was observed after 24 hours and it was 5 % higher compared to dry environment. Conclusions. 1) The artificial saliva environment and time of exposure to it, have a negative effect on the properties of elastomeric. 2) To maintain the effective orthodontic strength of elastics, they should be replaced every 12 hours.
Study of serum metabolic profiles of patients with non-small cell lung cancer with special emphasis on the smoking status of patients
Authors: Klupczynska Agnieszka , Kasprzyk Mariusz , Dyszkiewicz Wojciech , Grabicki Marcin , Batura-Gabryel Halina , Kokot Zenon J. , Matysiak Jan
Published: March 2019

The project entitled “Study of serum metabolic profiles of patients with non-small cell lung cancer with special emphasis on the smoking status of patients” is a study based on metabolomics, which is the latest of the “omics” technologies and involves a comprehensive analysis of small molecule metabolites of a specific biological sample. High-throughput and sensitive analytical techniques used in metabolomic investigations are powerful tools in the field of oncology and aids understanding what is happening in cancer cells and searching for new cancer markers. The aim of the project is to determine whether lung cancer patients have a distinct serum metabolic profile and whether this profile is associated with patients’ smoking status. The application of liquid chromatography-high-resolution mass spectrometry-based methodology along with advanced statistical methods will enable to select potential molecules that can be useful in early lung cancer detection.
Skin necrosis after SUPERknee procedure – typical versus modified surgical approach
Authors: Shadi Milud , Janusz Piotr , Koczewski Paweł , Walczak Michał , Kraśny Joanna , Kotwicki Tomasz
Published: March 2019

Introduction. SUPERknee procedure (SK) is a treatment for complex knee instability in children with congenital deformations. Due to wide surgical approach and long time of surgery (ST) the skin around the knee is in risk of ischemic necrosis (SN) or healing complications (HC). Aim. The purpose of the study is to compare incidence of SN in SK using typical and modified approach.Material and Methods. Sixteen patients underwent SK since 2015 till 2016, in mean age 8.1 (4.3–12.7) y.o. In 8 cases SK and in 8 SK combined with SUPERhip (SK+SH) was performed. In 6 patients (3 SK and 3 SK+SH) the approach was performed from one incision (OIA). In 10 patients (5 SK and 5 SK+SH) a modified approach was performed, involving additional skin incision (DIA). The occurrence of SN, ST and risk factors of HC were evaluated. Results. SN appeared in 2 cases treated with OIA (33%). There was no SN in DIA (0%). With this number of patients the difference was below level of significance, p = 0.1250, OR = 11.7. In one patient treated with SK+SH area of SN was 17.5 cm2. In the other patient treated with SK 35 cm2. Mean ST in SK was 3.4h (2.5–4.0) and in SK+SH 4.6h (4.0–5.5). ST of the surgery with OIA was 4.1h (2.5–5.5) and in DIA 3.7h (3.0–4.5), p = 0.4746. No additional risk factor relevant to SN was found.

Keywords: SUPERknee, SUPERhip, super knee, super hip, healing complications, skin necrosis.
A thousand words about the cardiopulmonary exercise test in respiratory system diseases
Authors: Tarchalski Jacek , Piorunek Tomasz , Guzik Przemysław
Published: March 2019

The cardiopulmonary exercise test (CPET) is designed to measure some physiological variables related to the function of the cardiovascular and respiratory systems during exercise. Usually, the CPET is performed either on a treadmill or a cycle ergometer. In this mini‑review, we describe a set of parameters which are most commonly used to quantify CPET. We also summarize clinical indications for this test and interpretation of the obtained results in patients with respiratory system diseases. The CPET, if made appropriately, may deliver valuable information helpful in the diagnosis, e.g., of unexplained dyspnea, and prognosis, e.g., in chronic obturatory pulmonary disease, pulmonary hypertension, or interstitial lung diseases.