bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunogenicity and Protection against Foot-and-Mouth Disease Virus in Swine Intradermally Vaccinated with a Bivalent Vaccine of Foot-and-Mouth Disease Virus Type O and A
Authors: Kim Dong-Wan , Cho Giyoun , Kim Hyejin , Lee Gyeongmin , Lim Tae-Gwan , Kwak Ho-Young , Park Jong-Hyeon , Park Sung-Han
Published: April 2023

Following the worst outbreak of foot-and-mouth disease (FMD), a highly contagious disease in cloven-hoofed animals caused by the FMD virus, from November 2010–April 2011, the Korean government enforced a mandatory vaccination policy. A bivalent (FMD type O and A; O + A) vaccine has been recently implemented. Although the FMD outbreak was suppressed by vaccination, the intramuscular (IM) injection presents side effects. Therefore, improving FMD vaccine quality is necessary. Here, we investigated the side effects and immune efficacy of the O + A bivalent vaccine using two different routes of administration: intradermal (ID) and IM. To compare the immune efficacy of the two inoculation routes, virus neutralization titers and structural protein (antigen) levels were measured. The protective efficacy of ID vaccines was confirmed using two viruses (FMDV O/AS/SKR/2019 and A/GP/SKR/2018) isolated in the Republic of Korea. Serological analysis revealed that both animals administered by ID and IM injections exhibited equal immune efficacy. A virus challenge test in the target animal (swine) revealed no (or extremely low) clinical symptoms. Swine in the ID injected group exhibited no side effects. In conclusion, we suggest that the ID route of vaccination is an effective alternative to the existing IM route, which is associated with more frequent side effects.
How Well the Constructs of Health Belief Model Predict Vaccination Intention: A Systematic Review on COVID-19 Primary Series and Booster Vaccines
Authors: Limbu Yam B. , Gautam Rajesh K.
Published: April 2023

This systematic review synthesizes the findings of quantitative studies examining the relationships between Health Belief Model (HBM) constructs and COVID-19 vaccination intention. We searched PubMed, Medline, CINAHL, Web of Science, and Scopus using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and identified 109 eligible studies. The overall vaccination intention rate was 68.19%. Perceived benefits, perceived barriers, and cues to action were the three most frequently demonstrated predictors of vaccination intention for both primary series and booster vaccines. For booster doses, the influence of susceptibility slightly increased, but the impact of severity, self-efficacy, and cues to action on vaccination intention declined. The impact of susceptibility increased, but severity’s effect declined sharply from 2020 to 2022. The influence of barriers slightly declined from 2020 to 2021, but it skyrocketed in 2022. Conversely, the role of self-efficacy dipped in 2022. Susceptibility, severity, and barriers were dominant predictors in Saudi Arabia, but self-efficacy and cues to action had weaker effects in the USA. Susceptibility and severity had a lower impact on students, especially in North America, and barriers had a lower impact on health care workers. However, cues to action and self-efficacy had a dominant influence among parents. The most prevalent modifying variables were age, gender, education, income, and occupation. The results show that HBM is useful in predicting vaccine intention.
Social Media Sentiment about COVID-19 Vaccination Predicts Vaccine Acceptance among Peruvian Social Media Users the Next Day
Authors: Lokmanoglu Ayse D. , Nisbet Erik C. , Osborne Matthew T. , Tien Joseph , Malloy Sam , Cueva Chacón Lourdes , Villa Turek Esteban , Abhari Rod
Published: April 2023

Drawing upon theories of risk and decision making, we present a theoretical framework for how the emotional attributes of social media content influence risk behaviors. We apply our framework to understanding how COVID-19 vaccination Twitter posts influence acceptance of the vaccine in Peru, the country with the highest relative number of COVID-19 excess deaths. By employing computational methods, topic modeling, and vector autoregressive time series analysis, we show that the prominence of expressed emotions about COVID-19 vaccination in social media content is associated with the daily percentage of Peruvian social media survey respondents who are vaccine-accepting over 231 days. Our findings show that net (positive) sentiment and trust emotions expressed in tweets about COVID-19 are positively associated with vaccine acceptance among survey respondents one day after the post occurs. This study demonstrates that the emotional attributes of social media content, besides veracity or informational attributes, may influence vaccine acceptance for better or worse based on its valence.
Gender Differences of the Effect of Vaccination on Perceptions of COVID-19 and Mental Health in Japan
Authors: Yamamura Eiji , Kohsaka Youki , Tsutsui Yoshiro , Ohtake Fumio
Published: April 2023

Vaccination has been promoted to mitigate the spread of the coronavirus disease 2019 (COVID-19). Vaccination is expected to reduce the probability of and alleviate the seriousness of COVID-19 infection. Accordingly, this might significantly change an individual’s subjective well-being and mental health. We observed the same individuals on a monthly basis from March 2020 to September 2021 in all parts of Japan. Then, large sample panel data (N = 54,007) were independently constructed. Using the data, we compared the individuals’ perceptions of COVID-19, subjective well-being, and mental health before and after vaccination. Furthermore, we compared the effect of vaccination on the perceptions of COVID-19 and mental health for females and males. We used the fixed-effects model to control for individual time-invariant characteristics. The major findings were as follows: First, the vaccinated people perceived the probability of getting infected and the seriousness of COVID-19 to be lower than before vaccination. This was observed not only when we used the whole sample but also when we used subsamples of males and a subsample of females. Second, subjective well-being and mental health improved. The same results were also observed using the subsample of females, whereas the improvements were not observed when using a subsample of males. This implies that females’ quality of life was more likely to be improved by vaccination than males’ one. The novelty of the work is to show the gender difference in the vaccination effects.
Analysis of Various Facial Expressions of Horses as a Welfare Indicator Using Deep Learning
Authors: Kim Su Min , Cho Gil Jae
Published: April 2023

This study aimed to prove that deep learning can be effectively used for identifying various equine facial expressions as welfare indicators. In this study, a total of 749 horses (healthy: 586 and experiencing pain: 163) were investigated. Moreover, a model for recognizing facial expressions based on images and their classification into four categories, i.e., resting horses (RH), horses with pain (HP), horses immediately after exercise (HE), and horseshoeing horses (HH), was developed. The normalization of equine facial posture revealed that the profile (99.45%) had higher accuracy than the front (97.59%). The eyes–nose–ears detection model achieved an accuracy of 98.75% in training, 81.44% in validation, and 88.1% in testing, with an average accuracy of 89.43%. Overall, the average classification accuracy was high; however, the accuracy of pain classification was low. These results imply that various facial expressions in addition to pain may exist in horses depending on the situation, degree of pain, and type of pain experienced by horses. Furthermore, automatic pain and stress recognition would greatly enhance the identification of pain and other emotional states, thereby improving the quality of equine welfare.
High Resolution Estimation of Ocean Dissolved Inorganic Carbon, Total Alkalinity and pH Based on Deep Learning
Authors: Galdies Charles , Guerra Roberta
Published: April 2023

This study combines measurements of dissolved inorganic carbon (DIC), total alkalinity (TA), pH, earth observation (EO), and ocean model products with deep learning to provide a good step forward in detecting changes in the ocean carbonate system parameters at a high spatial and temporal resolution in the North Atlantic region (Long. −61.00° to −50.04° W; Lat. 24.99° to 34.96° N). The in situ reference dataset that was used for this study provided discrete underway measurements of DIC, TA, and pH collected by M/V Equinox in the North Atlantic Ocean. A unique list of co-temporal and co-located global daily environmental drivers derived from independent sources (using satellite remote sensing, model reanalyses, empirical algorithms, and depth soundings) were collected for this study at the highest possible spatial resolution (0.04° × 0.04°). The resulting ANN-estimated DIC, TA, and pH obtained by deep learning shows a high correspondence when verified against observations. This study demonstrates how a select number of geophysical information derived from EO and model reanalysis data can be used to estimate and understand the spatiotemporal variability of the oceanic carbonate system at a high spatiotemporal resolution. Further methodological improvements are being suggested.
High-Temperature-Resistant Scale Inhibitor Polyaspartic Acid-Prolineamide for Inhibiting CaCO3 Scale in Geothermal Water and Speculation of Scale Inhibition Mechanism
Authors: Yan Jiawei , Tan Xiao , Qi Suitao
Published: April 2023

An excellent high-temperature-resistant scale inhibitor, polyaspartic acid-prolineamide (PASP-Pro), was synthesized by polysuccinimide (PSI) and L-prolineamide (L-Pro), and then characterized by 1H-NMR and FTIR analysis. The inhibition performance of PASP-Pro on CaCO3 precipitation was studied at different temperatures through static tests; at the same time, the influence of PASP-Pro on the crystallization process of CaCO3 was investigated by combining the electrical conductivity test of CaCO3 solution with different CaCO3 scale characterizations. The suitable synthesis and evaluation conditions for PASP-Pro were obtained, and a possible multi-stage scale inhibition mechanism of PASP-Pro for CaCO3 scale was then suggested. PASP-Pro has better thermal stability and high-temperature scale inhibition performance (exceeds 87% after pretreatment at 150 °C) than PASP. In addition, PASP-Pro exhibited a promising anti-scaling property by inhibiting the crystallization of CaCO3; the induction period and the nucleation period of the CaCO3 crystallization process were prolonged nearly four times. It was found from XRD patterns that vaterite, an unstable crystalline phase, gradually emerged with the addition of the scale inhibitors, and the aragonite crystals are clearly observed in SEM images. Finally, the possible multi-stage scale inhibition mechanism of PASP-based inhibitors was proposed, including coating impurities, electrostatic repulsion, and inhibiting dehydration and rearrangement of CaCO3 crystallization.
Reverse Salt Flux Effect on Dewatering Chlorella vulgaris in a Forward Osmosis System
Authors: Munshi Faris M. , Hwang Jae-Hoon , Stoll Stephanie , Lee Woo Hyoung
Published: April 2023

Microalgae shows a high potential to produce biofuel and forward osmosis (FO) has been proposed as a promising dewatering process for algal biomass separation from water. However, the effect of reverse salt flux (RSF) on algal biomass during the dewatering process using FO has not been completely explored. This study was to investigate the effect of different types of salt and their concentrations on algal biomass in terms of conductivity, settling velocity, and lipid contents in FS during a simulated FO-driven dewatering of Chlorella vulgaris microalgae. Three draw solution (DS) salts (NaCl, KCl and NH4Cl) were evaluated in RSF-simulating batch tests. The salt diffusion from the DS to the algal feed solution (FS) caused a static growth of algal biomass while increasing lipid content up to 14.8% at 8 mM NH4Cl. With the addition of the different salts, pH was maintained to the optimal algal thriving range (7.2–10.6), but the presence of salt stressed the algal cells and inhibited photosynthesis and algal growth within the experimental conditions. The settling velocity of the algal cells improved with the increase of salt content from 8 to 80 mM of each DS. It seemed that cell division could be accelerated in the presence of NH4Cl, and microscopic images showed a change in the algal cell size distribution, which may negatively affect algal settleability. DS salt in an FO-algal harvesting system should be selected based on the final algal properties and constituents required.
Research on the Application of CEEMD-LSTM-LSSVM Coupled Model in Regional Precipitation Prediction
Authors: Chen Jian , Guo Zhikai , Zhang Changhui , Tian Yangyang , Li Yaowei
Published: April 2023

Precipitation is a vital component of the regional water resource circulation system. Accurate and efficient precipitation prediction is especially important in the context of global warming, as it can help explore the regional precipitation pattern and promote comprehensive water resource utilization. However, due to the influence of many factors, the precipitation process exhibits significant stochasticity, uncertainty, and nonlinearity despite having some regularity. In this article, monthly precipitation in Zhoukou City is predicted using a complementary ensemble empirical modal decomposition (CEEMD) method combined with a long short-term memory neural network (LSTM) model and a least squares support vector machine (LSSVM) model. The results demonstrate that the CEEMD-LSTM-LSSVM model exhibits a root mean square error of 15.01 and a mean absolute error of 11.31 in predicting monthly precipitation in Zhoukou City. The model effectively overcomes the problems of modal confounding present in empirical modal decomposition (EMD), the existence of reconstruction errors in ensemble empirical modal decomposition (EEMD), and the lack of accuracy of a single LSTM model in predicting modal components with different frequencies obtained by EEMD decomposition. The model provides an effective approach for predicting future precipitation in the Zhoukou area and predicts monthly precipitation in the study area from 2023 to 2025. The study provides a reference for relevant departments to take effective measures against natural disasters and rationally plan urban water resources.
Hydrogeological Hazards in Open Pit Coal Mines–Investigating Triggering Mechanisms by Validating the European Ground Motion Service Product with Ground Truth Data
Authors: Tzampoglou Ploutarchos , Loupasakis Constantinos
Published: April 2023

This research focuses on the investigation of hydrogeological hazards in open pit coal mines. The study area is the Amyntaio sub-basin area, located in West Macedonia prefecture, Greece. A major part of the SE of this area is occupied by the Amyntaio open pit coal mine. In recent decades, the Amyntaio basin’s aquifer has been overexploited both by dewatering wells of the open pit coal mine and irrigation wells, triggering extensive land subsidence in an area that extends 3 km around the mine. Additionally, one of the biggest mining landslides worldwide occurred on the South-West slopes of the open pit on 10 June 2017. The current study investigates the land subsidence phenomenon and the landslide, highlighting the influence and the interaction of their causal factors which were strongly affected by the groundwater management. To estimate ground surface movement, Earth Observation data from the European Ground Motion Service, of the Copernicus European Union′s Earth observation program, were used for the period 1 January 2016–31 December 2020. The geologic, geotechnical and hydrogeologic data coming from the extensive ground truth survey have been incorporated with the Earth Observation data, highlighting the opposing mechanisms of the interacting geohazards.
Computational Modelling on Gasification Processes of Municipal Solid Wastes Including Molten Slag
Authors: Soon Genevieve , Zhang Hui , Law Adrian Wing-Keung , Yang Chun
Published: April 2023

The formulation of the CFD-DEM model, CD-MELT, is established in this study to include three-phase non-isothermal processes with simultaneous combustion and melting for gasification simulations. To demonstrate the model capability, CD-MELT is used to assess the need for slag recycling for the non-isothermal melting of municipal solid wastes (MSW) in a prototype waste-to-energy research facility. The simulation encompasses the full fixed-bed slagging gasification process, including chemical reactions and melting of MSW and slag. In order to assess the need for slag recycling, comparisons are made for the two cases of with and without, in terms of the slag mass, liquid slag volume fraction, exit gas composition, and temperature distribution in the gasifier. The prediction results enable the tracking of liquid molten slag as it permeates through the solids-packed bed for the first time in the literature as far as we are aware, which is crucial to address design considerations such as distribution of bed temperature and optimal location for slag-tap holes at the bottom, as well as potential slag clogging within the porous media. The model also predicts an uneven and intermittent slag permeation through the packed bed without the recycling, and provides a plausible explanation for the operators’ experience of why slag recycling is important for process stability. Finally, the predicted slag outlet temperature using the proposed CFD approach also agrees well with the measurement data published in an earlier case study for the same facility.
Descripción de las experiencias acerca de la sexualidad en adultos con talla baja
Authors: Cuji Tatayo Mercedes Michelle , Redrobán Pilatasig Marjorie Karla , Vaca Eliana Alexandra , Valencia Cabezas Génesis Brigith
Published: April 2023

El presente trabajo de investigación tiene como objetivo describir las experiencias de la sexualidad en las personas con talla baja. Se utilizó para la recolección de datos entrevistas semiestructuradas, con el fin de conocer a profundidad la problemática. La investigación es de tipo transversal-descriptivo, tiene un enfoque cualitativo y fenomenológico, el tipo de muestra es no probabilística con un método de muestreo por conveniencia, obteniendo de esta manera una muestra final de 3 mujeres de 32, 33 y 35 años. Los resultados relevantes de este estudio muestran que la educación sexual y el entorno familiar de la persona influye significativamente en el desarrollo de la sexualidad. Uno de los principales hallazgos en esta investigación es que la educación y orientación con respecto a la sexualidad se dio particularmente fuera de sus hogares. Otro dato encontrado es acerca de las relaciones de amistad, las respuestas indican que este proceso es más complicado en la infancia y adolescencia, especialmente en centros educativos donde estas personas sufren de bullying y aislamiento. Por último, se menciona que las relaciones de pareja se ven siempre involucradas en comentarios de toda índole, pero estas personas han decidido obviar para obtener un bienestar y estabilidad en sus relaciones.
Ansiedad y embarazo durante la adolescencia
Authors: Peralta Muguerza Jean Pierre , Farfán Casanova Olmedo Daniel
Published: April 2023

El embarazo adolescente se caracteriza por ser un período de transición y de gran inestabilidad que involucra distintos ámbitos de la vida adolescente. La presente investigación tuvo como objetivo determinar los tipos de ansiedad en adolescentes con embarazo deseado y no deseado, que asisten al área de consulta obstétrica del Centro de Salud Tipo-B, 24 de Mayo, del cantón 24 de Mayo de la provincia de Manabí, Ecuador. Este un tema de gran relevancia en la actualidad debido a que pocas adolescentes están preparadas para la maternidad, existiendo poca preparación y planificación para afrontar este importante proceso en sus vidas. Por tal razón, la concepción del embarazo en una edad caracterizada por la inestabilidad de algunos procesos como es la adolescencia, puede generar efectos en la esfera emocional de las adolescentes. Para el estudio se utilizó un enfoque mixto. La investigación es de tipo descriptiva, de corte transversal y utiliza los métodos de análisis, síntesis y estadística. La muestra de estudio se conforma por 25 mujeres embarazadas, con embarazos deseados y no deseados. Como resultado se encuentran ansiedad de tipo somática en niveles medios, tanto en el grupo de adolescentes con embarazo deseado como no deseado y ansiedad de tipo psíquica en las adolescentes con embarazos deseados
Ansiedad: Sintomatología, prevalencia y riesgo en los músicos afiliados a la Casa de la Cultura Ecuatoriana de Manabí
Authors: Mera García Jorge Daniel , García Cedeño María Leonila
Published: April 2023

La presente investigación va dirigida a todo el púbico que quiera tener una mirada más precisa del contexto portovejense en los artistas, ya que tuvo como objetivo determinar los niveles de ansiedad en la población de músicos afiliados a La Casa de la Cultura Ecuatoriana Benjamín Carrión del Núcleo de Manabí (CCE), siendo cuantitativo y de tipo descriptivo. El instrumento que se aplicó fue el inventario de Beck para la ansiedad. El cuestionario consta de 21 preguntas, proporcionando un rango de puntuación entre 0 y 63. El Inventario de Ansiedad de Beck es una herramienta útil para valorar los síntomas somáticos de ansiedad, tanto en desórdenes de ansiedad como en cuadros depresivos. La población de la presente investigación estuvo conformada por 100 músicos de la CCE de Manabí. Con esto se llegó a la conclusión de que, a pesar de presentar síntomas y signos fisiológicos, tales como dolor de cabeza, palpitaciones, miedo a perder el control y demás que son muy característicos de la ansiedad, que se reflejaban de forma casi nula y leve en la encuesta, los músicos de la ciudad, afiliados, no se encuentran con niveles de ansiedad. No obstante, es necesaria la continuidad de seguir realizando este tipo de estudios con determinada frecuencia debido a la alta posibilidad de que emerjan estados negativos que afecten la salud mental.
Gestión de proyectos en la Corporación Nacional de Electricidad, Manta-Manabí-Ecuador
Authors: Macias Moreira Martha Roxana , Alfonso Robaina Daniel
Published: April 2023

La aplicación de buenas prácticas de la Gestión de Proyectos garantiza el éxito de la ejecución de los mismos, es importante conocer el nivel de madurez en la aplicación de estándares y metodologías en gerencia de proyectos, como punto de partida para su optimización. Esta investigación fue realizada en la Unidad de Negocios Manabí de la Corporación Nacional de Electricidad, en Manta-Ecuador, durante marzo a diciembre 2021. La investigación planteó un estudio descriptivo y explicativo de tipo no experimental, transversal con un enfoque mixto, cualicuantitativo mediante la investigación biográfica – documental referente a la Gestión de proyectos y los modelos de madurez; y aplicación de evaluación de madurez a la gestión de proyectos. Se tomó como muestra a 25 funcionarios de las diferentes áreas involucrados en los estudios precontractuales y ejecución de proyectos con experiencia mínima de 2 años en dichos estudios; entre las técnicas que se utilizó está la encuesta, entrevista y análisis de registros. Se realizó la evaluación de madurez propuesta: Organizacional Project Management Maturity Model (OPM3), que dio como resultado un nivel de madurez medio.
Estrategias creativas de escritura en estudiantes de bachillerato
Authors: Ruíz Menéndez Nancy Mercedes , Vélez Villavicencio Carlina Edith
Published: April 2023

La investigación abarca las insuficientes estrategias creativas que han afectado el desarrollo de la escritura. El objetivo fue identificar el nivel que demuestran los estudiantes de bachillerato en las habilidades de escritura. El enfoque fue mixto; se aplicó el Test PROESC y entrevista a expertas en literatura infantil y docencia. La muestra la conformó 67 estudiantes de primer año de bachillerato con una edad de 14 y 15 años. Los resultados indicaron que tuvieron dificultades de dictado de palabras con ortografía reglada, frases con mayúscula, y de reglas ortográficas. Se concluyó, proponer estrategias creativas idóneas en el proceso de escritura, para que fomenten una capacidad de análisis en su área cognitiva y mejoren su habilidad de escritura, por tanto, al ser evidente que el grupo alcanzó un nivel alto en el dictado de palabras, pero por su edad y nivel deberían poseer mayor conocimiento de escritura, principalmente en la redacción.
El mal: una cuestión de perspectiva
Authors: Rodríguez Durango Pavel Eduardo
Published: April 2023

Al tratar acerca de la idea del mal en sí misma no se puede soslayar su multiplicidad de expresiones. Este artículo propone pensar este concepto desde varias dimensiones del quehacer humano, como la ética, la debilidad o fortaleza de la voluntad humana, la idea del bien, la praxis del mal, las narrativas literarias y la pregunta sobre el porqué de nuestra capacidad de cometer injusticias, de generar sufrimiento en los otros, el innatismo de la maldad en el seno de la razón, la condición de la naturaleza humana y su relación con la consecución del propio deseo, la meta/narrativa que expone la legitimidad o legalidad del imperio de la violencia y determina lo que es tolerable o no, desde pensadores como San Agustín, Maquiavelo, Hobbes, Kant, Schopenhauer, Spinoza, Bataille, Arendt, entre otros, para colegir que al fin, hablar del mal, exige reflexionar en torno a la decisión humana de actuar contra el bien.
Nota editorial
Authors: Fisgativa Carlos Mario
Published: April 2023

Este número misceláneo de la revista Disertaciones continua ahondando en la pluralidad de perspectivas y apuestas filosóficas que comprenden su línea editorial, dando cabida a textos que revisan discusiones epistemológicas, políticas, estéticas y relacionadas con el ejercicio filosófico situado en Latinoamérica. Nuevamente, contamos con artículos de autores de Argentina y Brasil, así como con una cuota de autores nacionales que aportan a la pluralidad de esta edición. Cabe destacar que continuamos con la apertura a la recepción y publicación de textos en portugués, dado que esta es una manera de incentivar diálogos de saberes desde las diferentes latitudes de nuestro continente.
Patient perspectives of skeletal muscle cramping in dialysis: a focus group study
Authors: Grandinetti Amanda , Hilliard-Boone Tandrea S. , Wilund Kenneth R. , Logan Dilani , St. Peter Wendy L. , Wingard Rebecca , Tentori Francesca , Keller San , West Melissa , Lacson Eduardo , Richardson Michelle M.
Published: April 2023

Background:

Skeletal muscle cramping is a common, painful and debilitating symptom experienced by people receiving dialysis. Neither a standardized, patient-endorsed definition of skeletal muscle cramping nor full understanding of patients’ perspectives of skeletal muscle cramping exist. We conducted focus groups, within a Kidney Health Initiative (KHI) project, to elicit skeletal muscle cramping experiences of people receiving dialysis as the basis for patient-reported outcome measure (PROM) development.

Methods:

Eligible participants (English-speaking adults aged 18-85 treated by dialysis and a skeletal muscle cramping episode within 30 days) were purposively recruited from a panel (L&E Research) of people receiving dialysis at home or in-center.

Standard qualitative methods were used to conduct virtual 90-minute sessions discussing: skeletal muscle cramping clinical characteristics; participants’ skeletal muscle cramping experiences; and feedback on a draft skeletal muscle cramping definition and a patient-facing conceptual model developed by the KHI project workgroup. We used qualitative thematic analysis.

Results:

There were 20 diverse participants in three focus groups. Universally-experienced skeletal muscle cramping attributes differed by dialysis setting in onset, worst pain rating, duration and timing. Variably-experienced attributes (applied to home and in-center dialysis) were: gross and fine motor impact, sleep disruption, mood-related themes of fear and annoyance/frustration/irritability. Avoidance/adaptive behaviors included reluctance or avoiding movement; adjusting what they ate or drink (e.g., yellow mustard, pickles, pickle juice, tonic water); heat application; massage; and cannabidiol use. The skeletal muscle cramping definition was endorsed and insightful suggestions for conceptual model collected.

Conclusions:

This qualitative study of in-center and home patients’ skeletal muscle cramping experiences identified universally- and variably-experienced attributes. The patient-endorsed skeletal muscle cramping definition can serve as a standard for assessment. These results provide the foundation to develop a PROM for regulatory use with people receiving maintenance dialysis who experience skeletal muscle cramping.
Targeted transcriptional analysis of IgA vasculitis, IgA nephropathy, and IgA dominant infection related glomerulonephritis reveals both distinct and overlapping immune signatures
Authors: Kung Vanderlene L. , Avasare Rupali , Friedman Marcia A. , Koon Stephanie Mengden , Neff Tanaya L. , Protzek Sara , Corless Christopher , Krajbich Victoria , Setthavongsack Naly , Ditmore Rebecca , Woltjer Randy , Andeen Nicole K.
Published: April 2023

Background:

IgA vasculitis (IgAV), IgA nephropathy (IgAN), and IgA-dominant infection-related glomerulonephritis (IgA-IRGN) have shared histopathologic features but differences in clinical management and prognosis. The most serious IgAV organ involvement is in the kidneys (IgAV nephritis). In this study, we hypothesized that targeted immune transcript profiling could aid in 1) predicting development of IgAV nephritis in patients with cutaneous IgAV, and 2) differentiating IgAN, IgAV, and IgA-IRGN.

Methods:

RNA was extracted from 24 formalin-fixed paraffin-embedded tissue specimens (16 kidney, 8 skin) from 21 patients with IgAV nephritis (n=7), IgAN (n=5), and IgA-IRGN (n=4), and IgAV skin biopsies from patients with (n=3) and without (n=5) IgAV nephritis. Differential gene expression and gene set enrichment analysis were performed on a total of 594 transcripts (Nanostring immunology panel) profiled using the nCounter system.

Results:

Skin biopsies in IgAV patients who develop kidney involvement exhibit reduced S100A8/S100A9, IL9, and KIR expression. The kidney tissue immune transcriptomes of IgAN, IgAV, and IgA-IRGN are largely overlapping. IgA-IRGN kidney biopsies are, however, uniquely enriched for transcripts involved in granulocyte chemotaxis.

Conclusion:

This study identifies immune transcript signatures that may predict IgAV nephritis in skin biopsies and distinguish IgA-IRGN from IgAN and IgAV in kidney biopsies.
The role of information technologies in education
Authors: Tsarova Yevelina , Alekseiko Vitalii , Sabadosh Yuliia , Kushnir Antonina , Yaroshuk Dmytro
Published: April 2023

In the article we find out the possibilities of using information technologies to modernize the educational process in higher education institutions. The article reveals the content of information technologies, describes the possibilities of their application, and shows their role in higher education institutions for the modernization of education. It is noted the functions inherent in the system of information provision of monitoring and quality control of education. The article distinguished the components of information technologies (hardware and software; applied information; the end user of information and the components of the national information system (modern telecommunications infrastructure; distributed computer network; system of national information resources); system-methodological. Information technologies are classified according to several features: the method of process in the information system; the step of treatment of organization tasks; the classes of hi-tech actions carried out; the kind of user interface). Priority directions in the field of informatization of education (introduction of multimedia technology, use of multimedia products in higher education institutions) have been identified. Aspects of information inequality are described (physical access, financial access, cognitive access, access to significant information, and political access). The significance of distance education for today is shown, and its principles are considered.
Categories and methods of civilizational approach in modern philosophical and historical discourse
Authors: Galiakberova Alfinur A. , Mukhametshin Azat G. , Asratyan Norair M. , Kornilova Irina V. , Galiev Rustem M.
Published: April 2023

The diverse contradictions of the modern world, social and international conflicts, the growing trends of both globalization and national isolation, the rapid development of communication technologies against the background of growing gap between poverty and wealth of the countries and within them are evidence of another crisis in the system of international relations, of the entire world order. The growth of entropy has once again raised the question of the lack of a holistic and systematic understanding of the processes of socio-historical development, and actualizes the need to analyze theories that consider the development of large socio-cultural communities. In this regard, it is important to study socio-philosophical and philosophical-historical theories and views, united in a civilizational approach. The dominance of the formational approach in Soviet historical science ended in the late 1980s. And in 1995 the Russian Academy of Sciences recognized that civilizational theory can serve as one of the conceptual principles for analyzing and describing the historical process in textbooks for schools and universities. The object of our article is the essence of the civilizational philosophical and historical concept. The subject is the discourse, in the space of which there is developed a methodology, and are analyzed the categories of the civilizational approach to history. We apply general theoretical research methods: analysis, synthesis, comparison, interpretation. It is shown that within the framework of the theory under consideration methodological differences are significant, so several theoretical varieties are identified and the key categories of the civilizational concept in them are interpreted differently.
Organizing the germans’ emotional world through the prism of the opposition ORDNUNG vs. CHAOS: Ambivalent emotion concepts
Authors: Mizin Kostiantyn , Slavova Liudmyla , Petrov Oleksandr , Yumrukuz Anastasiia
Published: April 2023

The authors prove the assumption that the linguo-cultural opposition ORDNUNG vs. CHAOS has a certain influence on the formation of such ethno-specific ambivalent emotion concepts (EC) SEHNSUCHT, FERNWEH AND HEIMWEH in the German linguo-culture. Due to the applied methodology (definitional and contextual analyses of EC names) it was established that the German chaos and metaphysical fear (ANGST) oppose a kind of "safety-cosiness quartet", which is represented by concepts SICHERHEIT, GEBORGENHEIT, GEMÜTLICHKEIT and ZUVERLÄSSIGKEIT. It was revealed that the universal principle of perception of the objective world ONE’S OWN vs. ALIEN serves as the basis for the opposition ORDNUNG vs. CHAOS and its derivative ANGST vs. SICHERHEIT & GEBORGENHEIT & GEMÜTLICHKEIT & ZUVERLÄSSIGKEIT. This principle caused "disruption" of the inner world of the German linguo-culture representatives because, on the one hand, they strive for a sense of safety, security, comfort, and stability, which generates "their own" world, but, on the other hand, they constantly try to go beyond the latter, since the "alien" world is associated not only with chaos and danger but also with new sensations and experience. Such an emotional "disruption" of the German people between metaphysical fear and a "safety-cosiness quartet", to some extent, gave rise to the ambivalence of the EC SEHNSUCHT, FERNWEH and HEIMWEH.
Research on the functional semantic field of spatial orientation in russian and chinese languages
Authors: Yanrong Gao , Morugova Y.A. , Duo Li
Published: April 2023

According to Bondarko's functional grammar theory, combined with the corpus of the Russian State Corpus and the BCC Corpus of Peking University, this paper discusses the language expression means of each subfield of the functional semantic field of spatial orientational category in Russian and Chinese Languages, and constructs the structure of directional functional semantic field. The research results of this paper will help Chinese students better grasp the grammatical structure of Russian spatial direction prepositions. At the same time, This paper systematically compares and analyzes the characteristics of the expressions about the directional functional semantic field in the two languages, provides theoretical guidance for Chinese college students to learn Russian, and provides theoretical support for teachers engaged in Russian teaching.
Strategy and Stages of Clinical Laboratory Service Development in BSSR, Ukrainian SSR and Other Republics of the Soviet Union: Significance of Using Organizational Decisions Experience in Contemporary Conditions
Authors: Камышников В.С.
Published: April 2023

В I разделе статьи, посвященном истории становления клинической лабораторной диагностики в БССР, показана значимость достижений отечественной медицинской химии для развития лабораторной медицины, а также эффективность совместного сотрудничества специалистов разных регионов СССР в решении вопросов организационного характера. Отражено основное содержание этапов формирования службы клинической лабораторной диагностики, отмечены достигнутые успехи в области информационной (редакционно-издательской) деятельности. Представлены сведения о ходе формирования единой стратегии управления деятельностью клинико-лабораторной службы в России и Беларуси. Акцентировано внимание на значимости деятельности кафедр клинической лабораторной диагностики институтов усовершенствования врачей, и прежде всего БелГИУВ (БелМАПО), в подготовке врачей-лаборантов. Охарактеризованы основные организационно-методические мероприятия, проведенные в период 1968–1990 гг. Во II разделе статьи содержится обширная информация о развитии лабораторной клинико-диагностической службы в Советской Украине, в III разделе – о формировании клинико-лабораторной службы в странах Прибалтики, Армении и Казахстане. В заключительной части статьи приводится перечень основных мероприятий, составляющих этапы развития специальности и службы клинической лабораторной диагностики в республиках бывшего СССР.

The first section of the article, devoted to the history of clinical laboratory diagnostics establishment in the BSSR, reveals the significance of domestic medical chemistry achievements in developing laboratory medicine as well as the effectiveness of specialists mutual cooperation from different regions of the USSR solving organizational issues. The main content of clinical laboratory diagnostics service creation stages is reflected; the achievements in informational (editorial and publishing) activities are noted. Materials about stages of creating a unified strategy of clinical laboratory service activity management in Russia and Byelorussia are presented. An emphasis is laid on the importance of clinical laboratory diagnostics departments activities of advanced medical training institutions, and, primarily, the Belarusian State Institute for Postgraduate Medical Education (Belarusian Medical Academy of Postgraduate Education), in laboratory doctors’ training. The main organizational and methodological measures taken during 1968-1990 are characterized. The second section of the article contains extensive information about the development of the laboratory clinical diagnostic service in Soviet Ukraine, and the third one about the formation of the clinical and laboratory service in the Baltic countries, Armenia and Kazakhstan. The final part of the article provides a list of main activities constituting stages of development of the specialty and the service of clinical laboratory diagnostics in the former USSR republics.
Relación entre los estilos educativos parentales y los roles asociados con la dinámica de violencia escolar en estudiantes de 1ro a 3ro de Bachillerato, en el cantón Paute, Ecuador
Authors:   , Iñiguez Vélez Diego Fernando
Published: April 2023

El bullying es un comportamiento no deseado y agresivo entre niños y adolescentes en edad escolar que implica un desequilibrio de poder real o percibido; la conducta puede ser esporádica o persistente y tiene graves consecuencias en las víctimas. El estudio tuvo como objetivo indagar si los estilos educativos parentales se asocian con los roles que los estudiantes asumen en la violencia escolar en estudiantes del 1ro a 3ro de bachillerato, en el cantón Paute durante el período escolar 2019-2020. El estudio fue de diseño no experimental, de enfoque cuantitativo, de tipo correlacional. El instrumento que se utilizó para medir el acoso escolar fue el BULL-S, mientras que los estilos de socialización parentales se midieron con el cuestionario ESPA29. Entre los principales resultados se obtuvieron los siguientes: 55,4% de los adolescentes tenían de 16 a 18 años de edad; 55% del total eran del género masculino; 70,1% vivían en zonas urbanas; 56,7% vivían con ambos padres y 5,2% había repetido de grado alguna vez. Los niveles bajos de cada dimensión del BULL-S fueron los más frecuentes. El estilo autoritario fue el predominante en madres (86,1%) y en padres (58,9%). Se halló que existe una asociación significativa entre los estilos parentales de madres y padres (p=0,018), entre el estilo parental del padre y la edad de los escolares (p<0,001) y entre los estilos parentales de la madre y la dimensión agresora del bullying (p<0,001). El estudio permitió sostener que el estilo autoritario afecta significativamente el comportamiento agresivo de los escolares.
ПІДХОДИ ДО ОЦІНКИ ВТРАТ У СФЕРІ ЗАЙНЯТОСТІ УКРАЇНИ ВНАСЛІДОК ВІЙСЬКОВИХ ДІЙ
Authors: Богуш Л. Г.
Published: April 2023

У статті досліджені та узагальнені підходи до оцінки втрат у сфері зайнятості України внаслідок військових дій. Генеровані збройним конфліктом негативи і втрати прямо чи опосередковано здійснюватимуть довготривалий вплив на якість відтворення вітчизняного людського потенціалу, його продуктивної реалізації в господарюванні та позаекономічних сферах життєдіяльності. Опрацювання методологічних і методичних підходів до систематизації збитків і втрат сфери зайнятості України внаслідок військових дій на її території створить передумови для якнайповнішого врахування генерованих ними нагальних і віддалених проблем та ризиків у послідовній стратегії та державній політиці повоєнного відродження, а також прискорення соціально-економічного розвитку. В цьому контексті доцільно виокремлювати суспільні витрати на забезпечення функціонування та підтримання сфери зайнятості в умовах воєнного стану, частина з яких є вимушеними в рамках якнайшвидшого підвищення ефективності функціонування економіки країни за критеріями оптимізації її кризостійкості та обороноздатності. Водночас слід виділяти прямі втрати у сфері зайнятості під час війни, спричинені насамперед: загибеллю, інвалідизацією робочої сили; знищенням, скороченням підприємств, закладів, а також пропозиції робочих місць на територіях ведення бойових дій та в регіонах масової евакуації цивільного населення; видатками на оплату праці, компенсації, адресну допомогу вимушено незайнятим найманим працівникам, підприємцям, самозайнятим. Опосередковані втрати від збройного конфлікту охоплюють: зниження продуктивності та оплати праці, скорочення загального та оплачуваного робочого часу, посилення плинності кадрів, поширення в територіальних громадах проявів структурного безробіття, маргіналізації, декваліфікації робочої сили; збитки від завдання шкоди життю, здоров’ю, відтворенню, психофізіологічному, професійно-кваліфікаційному та іншим складовим продуктивного потенціалу робочої сили у різностроковій перспективі повоєнного періоду; різноманітні генеровані військовим діями прояви погіршення соціально-економічного середовища життєдіяльності та відтворення робочої сили. За впливом на перспективи повоєнного відродження та прискорення соціально-економічного розвитку України найбільшої значущості набувають втрати сфери зайнятості від: загибелі, інвалідизації, скорочення тривалості життя, погіршення якості життєдіяльності, відтворення, професійно-кваліфікаційного потенціалу робочої сили; знищення, скорочення виробничої бази, руйнування схем і механізмів постачання, збуту, логістики підприємств, закладів, окремих видів економічної діяльності та ланок спеціалізації територіальних господарських підсистем і країни в цілому; підвищення страхових та інвестиційних ризиків господарювання.
НАПРЯМИ ВДОСКОНАЛЕННЯ МОТИВАЦІЇ ПРАЦІ НА ПІДПРИЄМСТВІ СФЕРИ ПОСЛУГ: ОСОБЛИВОСТІ РЕАЛІЗАЦІЇ В КРИЗОВИЙ ПЕРІОД
Authors: Соколюк К. Ю. , Додон О. Д. , Соколюк І. Ю.
Published: April 2023

У даній роботі розглянуто основні напрями удосконалення системи мотивації праці в кризовий період на прикладі підприємств сфери послуг. Визначено, що традиційні методи мотивації праці такі як нематеріальні та матеріальні в кризових умоває є недостатніми. На думку авторів, до нематеріальних варто віднести наступні заходи: мотиваційні наради, вітання зі знаменними датами, можливість для професійного зростання, публічна похвала кращих працівників, комфортні умови праці, заходи для підтримки та підвищення командного духу, гнучкий графік, додаткові вихідні, надання корпоративних знижок на послуги компанії, налагоджений зворотній зв’язок. В умовах війни та супутніх соціально-економічних кризових явищ особливо актуальним, на думку авторів, є морально-психологічна підтримка працівників. Зокрема, такі заходи як забезпечення комфортних умов для роботи та забезпечення безпеки для рідних – є одними із пріоритетних напрямів нематеріальної мотивації. На думку авторів, система мотивації для ефективної роботи підприємства має бути гармонізована за всіма рівнями – починаючи від підсистеми мотивації окремо взятого працівника та закінчуючи системою мотивації усього підприємства. Відповідно проведених досліджень, авторами зроблено висновок, що керівнику підприємства сфери послуг доцільно застосувати чотири основні методи поліпшення мотивації: матеріальний метод – метод, в якому застосовується система стимулювання співробітників підприємства, заснована на теорії підкріплення; цільовий метод – це метод регулювання поведінки співробітників за допомогою постановки цілей, або управління за цілями; метод різноманіття та комплексного об’єднання ділових процесів, в основі якого лежить зміна характеристик роботи; метод партнерства в управління – метод залучення працівників в управління, тобто їх участь у спільному прийнятті рішень. Такі заходи матимуть ряд позитивних ефектів: сприятимуть створенню механізму професійного росту всіх працівників; запобігатимуть конфліктам між керівниками та працівниками; сприятимуть задоволеності працівників працею.