bluuebunny/crossref_metadata_2025 huggingface dataset:
Imaging manifestations of neonatal necrotizing enterocolitis to predict timing of surgery
Authors: Yu Lei , Liu Chao , Cui Yanhua , Xue Linlin , Ma Lishuang
Published: September 2022

Background. To find the predictor of optimal surgical timing for neonatal necrotizing enterocolitis (NEC) patients by analyzing the risk factors of conservative treatment and surgical therapy.
Methods. Data were collected from 184 NEC patients (Surgery, n=41; conservative treatment, n=143) between the years 2015 and 2019. Data were analyzed by univariate analysis, and multivariate binary logistic regression analysis.
Results. Univariate analysis showed that statistically significant differences between the surgery and conservative treatment groups. The results of multivariate Logistic regression analysis indicated intestinal wall thickening by B-ultrasound and gestational age were independent factors to predict early surgical indications of NEC (p < 0.05). The true positive rate, false positive rate, true negative rate and false negative rate in the diagnosis of necrotic bowel perforation guided by DAAS (Duke abdominal X-ray score) ≥7 and MD7 (seven clinical metrics of metabolic derangement) ≥3 were 12.8%, 0.0%, 100.0% and 87.2%, respectively.
Conclusions. In summary, the ultrasound examination in NEC children showing thickening intestinal wall and poor intestinal peristalsis indicated for early operation.
Futuridad gay en Melodrama (1982) de Luis Zapata
Authors: Rivera Óscar
Published: September 2022

Aunque Melodrama (1982) homenajea a los melodramas cinematográficos de la época de oro en México, su juego estilístico con lo visual, forma teatral y literaria, así como su representación del deseo (homo)sexual, desestabiliza las inscripciones ideológicas dominantes que impulsó el melodrama. Así, sugiero que Melodrama no sólo es homenaje y parodia del género propio, sino que socava las nociones fijas de género y sexualidad inherentes dentro de ésta. Melodrama afecta no solamente la comprensión de lo que es ser “heterosexual”, sino también cómo se entiende un cuerpo, una identidad y un deseo homosexual.
Gay Futurity in Melodrama (1982) by Luis Zapata
Abstract
Although Melodrama (1982) pays homage to the cinematographic melodramas in Mexico’s Golden Age, its stylistic play on visual, theatrical, and literary form, as well as its portrayal of queer (homo)sexual desire, destabilizes the dominant ideological inscriptions that propelled the melodrama. Thus, I suggest that Melodrama is not only a tribute and parody of its own genre but also that it eradicates the fixed notions of gender and sexuality inherent within it. Melodrama affects not only the understanding of what it is to be “straight” but also how a gay body, identity, and desire is understood.
Recibido: 4 de febrero de 2022Dictaminado: 19 de mayo 2022Aceptado: 27 de junio 2022
Korelasi Kadar Protein C-Reaktif dengan Rasio Kolesterol Total / HDL pada Penyandang Obes di RSUP Dr M Djamil Padang
Authors: Oktavia Nanda , Nasrul Ellyza , Efrida Efrida
Published: September 2022

C-reactive protein is an acute-phase protein produced by the liver in response to inflammation. Dyslipidemia can trigger the inflammatory reaction in the blood vessels, causing atherosclerosis. The ratio of total cholesterol/High Density Lipoprotein (HDL) is considered as one of the sensitive predictor lipid ratio for the cardiovascular disease risk factor. Objectives: To determined the correlation of C reactive protein between cholesterol levels with total cholesterol/HDL ratio in obese people. Methods: This study was an analytical study with a cross-sectional design of 59 people who met the inclusion and exclusion criteria at the RSUP Dr. M. Djamil Padang from January to September 2019. Research subjects consisted of first degree obesity (25.0 ≤IMT <30.0 kg/m2) and second degree (≥30.0 kg/m2). C reactive protein levels were measured as high-sensitivity C-reactive protein. Total cholesterol and HDL levels were measured using automated clinical chemicals with the enzymatic colorimetric method. Data were analyzed by Pearson, significant if p <0.05. Results: The study subjects were 59 people (17 men and 22 women) with an average age was 35 (8.04) years. CRP levels in stage II obesity were slightly higher than grade I, with a mean difference between groups of 0.26 mg/L (95% CI: -1.80-1.2; p=0.74). The average ratio of total cholesterol/HDL levels in the obese group I and II was 5.13 and 4.80 (p=0.93). The correlation showed a very weak positive (r=0.12) and was statistically not significant (p=0.35). The results of the subanalysis showed relatively similar patterns between the first-degree obesity population (r=0.10; p=0.58) and second-degree (r=0.16; p=0.41). Conclusion: There is no significant correlation between protein C-reactive and total cholesterol/HDL ratio.Keywords: Obesity, C-Reactive Protein, total cholesterol/HDL ratio
Models for Estimation of Lift and Drag Coefficients for Low-Reynolds-Number Cambered Plates
Authors: Balla Esztella , Vad János
Published: September 2022

Empirical models capable of predicting the lift and drag coefficients of circular-arc cambered plate blades are presented, together with the detailed documentation of the related wind-tunnel technique and data evaluation. The blade profiles are equipped with rounded leading and trailing edges. The empirical models offer an easy-to-use tool for preliminary design of low-solidity low-speed blade cascades. By means of the models, the lift-coefficient range of 0–1.3 is covered, associated with the drag coefficient varying between 0.02 and 0.14. The validity ranges of the empirical models are as follows: Reynolds-number between [Formula: see text] and [Formula: see text], relative camber ranging from 0 to 8%, and angle of attack between 0 and 8 deg. The force coefficients are expressed as a function of relative camber, angle of attack, and Reynolds-number. The models assume linear relationships between the Reynolds-number and the force coefficients, as inspired by the literature and justified by statistical means. The dependence of the force coefficients on the angle of attack and the relative camber is expressed by incorporating second-order polynomials. The trends of force changes with Reynolds-number are analyzed. The cases of apparently extraordinary trends in the Reynolds-number dependence (i.e., increasing drag and decreasing lift with increasing Reynolds-number) are discussed in detail. A method for the determination of the confidence intervals related to the models is presented, and a detailed uncertainty analysis is provided. On this basis, the relative errors of the force coefficients can be quantified in a case-specific, empirical manner.
Low-Order Modeling of Dynamic Stall on Airfoils in Incompressible Flow
Authors: Narsipur Shreyas , Gopalarathnam Ashok , Edwards Jack R.
Published: September 2022

Airfoil dynamic stall in incompressible flow is characterized by two interacting viscous flow phenomena: time-varying trailing-edge separation and the shedding of intermittent leading-edge-vortex structures. In the current work, a physics based low-order method capable of modeling the interactions between the two flow phenomena is developed with the aim of predicting dynamic stall with only a few empirical tuning parameters. Large computational datasets are used to understand the flow physics of unsteady airfoils so as to augment an inviscid, unsteady airfoil theory to model the time-dependent viscous effects. The resulting model requires only three empirical coefficients for a given airfoil and Reynolds number, which could be obtained from a single moderate-pitch-rate unsteady motion for that airfoil/Reynolds number combination. Results from the low-order model are shown to compare excellently with computational and experimental solutions, in terms of both aerodynamic loads and flow-pattern predictions. In addition to formulating a method with limited empirical dependencies, the current research provides valuable insights into the flow physics of unsteady airfoils and their connection to rapidly predictable theoretical parameters.
Ice Crystal Drag Model Extension to Snowflakes: Experimental and Numerical Investigations
Authors: Aguilar Boris , Trontin Pierre , Reitter Louis , Köbschall Kilian , Dezitter Fabien , Roisman Ilia , Villedieu Philippe
Published: September 2022

To ensure safe flight under snowy conditions, aircraft manufacturers must demonstrate that each engine and its air inlet system can operate throughout the flight power range of the engine (including idling) in both falling and blowing snow conditions. This study is part of an effort to develop models for snow accretion. The focus here is on the modeling of snowflake transport by the carrier airflow and more specifically on the modeling of the drag coefficient of snowflakes. Based on comparisons between numerical and experimental results, we show that, provided that the complex shape of the snowflakes is accounted for, the models initially developed for ice crystal icing can also be used to estimate the drag coefficient of a snowflake. We also propose a methodology to estimate the geometric parameters of the drag models from two-dimensional images of the particles, which in general are the only available experimental data.
Flow and Noise Characteristics of Blunt-Trailing-Edge Flat Plate with an Upstream Cylinder
Authors: Zhang Yaowen , Li Yong
Published: September 2022

This paper experimentally studies the flow interaction and the associated noise between an upstream cylinder and a downstream finite-chord-length flat plate with a blunt trailing edge in an acoustic wind tunnel. The configuration of this cylinder–plate model varies by changing the cylinder diameter [Formula: see text] and the vertical gap [Formula: see text] between the cylinder and the flat-plate surface. Aerodynamic noise was measured using far-/near-field microphone arrays. The results show that, as compared to the single flat plate, the trailing-edge noise associated with the vortex shedding from the flat plate is significantly suppressed when the gap is [Formula: see text]: that is, when the cylinder is vertically close to the flat-plate surface. In addition, the corresponding vortex shedding frequency [Formula: see text] decreases visibly. The leading-edge interaction noise due to the cylinder wake impingement gradually loses its dominance with the increase of the vertical gap. Compared to the single cylinder, the vortex shedding frequency from the upstream cylinder [Formula: see text] in the cylinder–plate model is reduced slightly due to the acoustic feedback from the plate leading edge. Flow characteristics were measured using surface microphones and particle image velocimetry (PIV) techniques. The pressure fluctuations along the plate surface present the dominant frequencies at the leading edge and the trailing edge, respectively, and verify the changes in the peak frequency and its noise level. The PIV technique clearly shows the variation of the vortex–body interaction at the leading edge and the vortex shedding at the trailing edge, revealing the underlying flow mechanism responsible for the observed noise changes and frequency shifts.
CULTURAL AND GEOGRAPHICAL IMAGE OF SIBERIA IN THE LANGUAGE CONSCIOUSNESS OF RUSSIAN STUDENTS: DIACHRONIC ASPECT
Authors:   Herzen State Pedagogical University of Russia (St. Petersburg, Russia), Vasileva G.M. , Vinogradova M.V. ,   Russian State Hydrometeorological University (St. Petersburg, Russia)
Published: September 2022

Statement of the problem. This article traces the dynamics of the stereotypical component of the cultural and geographical image of Siberia in the linguistic consciousness of different generations of Russian students, which is conducted by benchmarking the data of free-associative experiments. The purpose of the article is to reconstruct the cultural and geographical image of Siberia in the linguistic consciousness of Russian students in order to reveal its possible dynamics. Methodology (materials and methods). Reconstruction of the cultural and geographical image of Siberia is conducted with the support of the free-associative experiment method with the utilization of three dictionaries of associative norms and data of the in-house experiment. Research results. Comparison of the associative fields’ main zones of the stimulus “Siberia” demonstrated a presence of not only certain concurrences but also significant changes in the content of association directions as well as their presence/absence in the linguistic consciousness of different generations of students. Conclusions. With the consistency of merely geographical perceptions of Siberia revealed among different generations of students, a notable dynamic of their culturological knowledge and phycological perception enclosed in the comprehensive cultural and geographical image of Siberia was distinguished. Authors’ contribution. The concept of the article, its theoretical comprehension and experimental implementation belongs to the authors of the article.
THE VIEW OF LIFE IN THE LANGUAGE CONSCIOUSNESS OF TEACHERS IN THE KRASNOYARSK REGION
Authors:   Gymnasium No. 10 named after A.E. Bochkin, Divnogorsk (Krasnoyarsk, Russia), Ustyantseva E.V.
Published: September 2022

Statement of the problem. The study of ideas about LIFE in the professional linguistic consciousness based on the materials of the “Associative Dictionary of the Professional Group “Teacher “of the Krasnoyarsk Territory”. The purpose of the article is to describe the associative field LIFE on the basis of direct and reverse reactions, as well as their comparison in the linguistic consciousness of teachers of different subject disciplines. The results of the study showed that the primary ideas about LIFE are happiness and love, meaning of existence, health, sports and desire to change life for the better. These representations of teachers from different educational areas differ. This can be explained by the peculiarities of the perception of reality and the specifics of the subjects taught.
Horner’s syndrome secondary to T1-T2 intervertebral disc prolapse
Authors: Anto Mariette , Manuel Adarsh , Jayachandran Akarsh , Thomas Santhosh George , Joseph Anu , Thankachan Anjitha , Bahuleyan Biji
Published: September 2022

Background:

T1-T2 intervertebral disc prolapse (IVDP) is a rare clinical condition. Horner’s syndrome is an extremely rare clinical finding in these patients.

Case Description:

A 56-year-old man presented with the left C8 T1 radiculopathy, left hand grip weakness, and ipsilateral Horner’s syndrome. Magnetic resonance imaging of the spine showed a contrast-enhancing lesion in the left T1 foramen compressing the left T1 nerve root. He underwent left T1 hemilaminectomy, upper half of left T2 hemilaminectomy and removal of the left foraminal lesion. A biopsy of the lesion was sent for histopathological diagnosis which revealed tissue consistent with disc material. Postoperatively, he had near-complete recovery with residual minimal Horner’s syndrome.

Conclusion:

T1-T2 IVDP should be considered in the differential diagnosis when a patient presents with C8 T1 radiculopathy and Horner’s syndrome.
PROGNOSTIC SIGNIFICANCE OF SERUM MAGNESIUM DEFICIENCY IN PATIENTS WITH HEART ARRHYTHMIAS TAKING CLASS III ANTIARRHYTHMIC DRUGS
Authors:   Grodno State Medical University, Grodno, Belarus, Kalatsei L. V. , Snezhitskiy V. A. ,   Grodno State Medical University, Grodno, Belarus
Published: September 2022

Aim: To determine the prevalence of serum magnesium deficiency in patients with ischemic heart disease and/or arterial hypertension and cardiac arrhythmias taking class III antiarrhythmic drugs and to establish the prognostic value of hypomagnesaemia for the development of drug-induced QT prolongation and ventricular arrhythmias. Material and Methods: The study included 117 patients with ischemic heart disease and/or arterial hypertension and cardiac arrhythmias taking class III antiarrhythmic drugs (amiodarone or sotalol). All patients underwent clinical, laboratory and instrumental studies, including the determination of serum magnesium levels. Depending on the magnesium levels, all patients were divided into 3 groups. Group A (n=21) included patients with serum magnesium below the reference values (<0.75 mmol/l), group B (n=77) – patients with normal magnesium levels (0.75 – 1.0 mmol/l), group C (n=19) – those with magnesium levels above the reference values (≥ 1.0 mmol/l). Results: The incidence of hypomagnesaemia among patients with cardiac arrhythmias was 18%. Serum magnesium levels significantly correlated with the intake of loop diuretics (R=-0.3, p=0.001). In patients with serum magnesium deficiency, higher values were observed for the duration of the corrected QT and JT interval (p<0.001), the interval T peak - T end (p<0.01), as well as the cardiac electrophysiological balance index (p<0.001). Magnesium level <0.75 mmol/l was associated with a risk of drug-induced QT interval prolongation greater than 500 ms in patients receiving antiarrhythmic therapy (OR - 5.87 [95% CI 2.45–13.99]), life-threatening ventricular arrhythmias (OR - 3.81 [95% CI 1.90-7.62]) and non-sustained polymorphic ventricular tachycardia (OR - 4.06 [95% CI 1.77-9.29]). Conclusion: In patients with cardiac arrhythmias taking class III antiarrhythmic drugs, hypomagnesaemia is a predictor of the development of drug-induced QT interval prolongation and life-threatening ventricular arrhythmias including non-sustained polymorphic ventricular tachycardia. Routine determination of serum magnesium levels in patients taking antiarrhythmic drugs may be of value in predicting and preventing drug-induced life-threatening ventricular arrhythmias.
CLINICAL EFFECTIVENESS OF REVASCULARIZING AUTOMYELOTRANSPLANTATION
Authors:   Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Belarus, Kamiandrouskaya A. A. , Fedzyanin S. D. ,   Vitebsk State Order of Peoples’ Friendship Medical University, Vitebsk, Belarus
Published: September 2022

Background. The Global Vascular Guidelines (2019) proposed the term “critical limb-threatening ischemia”, which leads to death or amputation within 12 months. Only half of the patients undergo limb revascularization; the rest receive conservative treatment, the effectiveness of which is extremely low. In this regard, it is necessary to develop alternative methods of surgical treatment based on the use of cellular technologies. Aim. To evaluate the clinical efficacy of revascularizing automyelotransplantation in the complex treatment of patients with chronic wounds associated with diabetic angiopathy of the lower extremities. Material and methods. The study included 100 patients suffering from diabetic angiopathy of the lower extremities and diabetes mellitus type 2. Chronic wounds of the lower extremities were detected in 25 patients of the main group and 32 patients in the comparison group. The size of chronic wounds in the main group before the start of treatment ranged from 0.5 to 3.5 cm2 (median (Me) 2.1 [1.5; 2.5] cm2), in the comparison group it varied from 0.7 to 3.5 cm2 (Me 2.1 [1.7; 2.6] cm2). There were no statistical differences between the groups (pMann-Whitney=1.0). Results. In the main group, chronic wounds healed in 12 patients (48%), decreased in size in three cases and remained without dynamics in one case. In six patients the purulent-necrotic process progressed, which led to amputation of the limb at the hip level. Three patients died. Among 32 patients with chronic wounds in the comparison group healing of chronic wounds or reduction in their size were not observed. In 10 people, the size of the defects did not change; in seven cases the purulent-necrotic process progressed, which led to the amputation of the limb. In two patients chronic wounds occurred after hospitalization. Fifteen patients died. The article presents descriptions of clinical cases. Conclusion. The use of revascularizing automyelotransplantation in the complex treatment of patients with diabetic angiopathy of the lower extremities has a positive effect on the dynamics of the wound process in chronic wounds.
FEATURES OF CLINICAL SYMPTOMS AND HEMATOLOGICAL INDICATORS IN COVID-19 ASSOCIATED PNEUMONIA
Authors:   Grodno State Medical University, Grodno, Belarus, Karpovich A. A. , Shyshko V. I. ,   Grodno State Medical University, Grodno, Belarus, Ershova M. V. ,   Grodno University Clinic, Grodno, Belarus
Published: September 2022

Purpose of research. Assessment of the features of the clinical course of pneumonia associated with COVID-19, as well as hemogram and lymphocytic index parameters in patients with the first wave of SARS-CoV-2 coronavirus spread. Material and methods. The study included 60 patients with COVID-19 associated pneumonia (Group 1), 30 patients with bilateral community-acquired pneumonia not associated with COVID-19 (Group 2). The clinical manifestations of pneumonia and the parameters of the complete blood count were evaluated. Results. At the onset of the disease the patients of Group 1 were found to have fever (p=0.006) and dry cough (p=0.028) more often, the severity of fever being higher (p=0.019), crepitus being less frequently detected during auscultation of the lungs (p=0.03), slower regression of symptoms of pneumonia being characteristic (p=0.02) as well. Complete blood count more often determined a dysregenerative shift of the leukocyte formula to the left, manifested by an increase in the relative number of stab forms of neutrophils with a normal or reduced total number of leukocytes. As many as 45.0% patients of Group 1 showed elevated lymphocytic index (so-called excessive activation), 48.3% patients had reduced lymphocytic index, which indicates a tendency to the incompleteness of the immune responses. The inverse relationship between the lymphocytic index and the severity of pneumonia according to computed tomography (r=-0.34, p=0.0018) was established. Conclusion. Patients with COVID-19 associated pneumonia have specific clinical symptoms and hematological blood parameters as compared to those with community-acquired nonspecific pneumonia.
EXPERIMENTAL STUDY OF THE ABILITY OF OLIGOPEPTIDE TRPASP-PHE-ASP TO BIND INTERLEUKIN-8
Authors:   Belarusian State Medical University, Minsk, Belarus, Ryabtseva T. V. , Taganovich A. D. ,   Belarusian State Medical University, Minsk, Belarus, Makarevich D. A. ,   Belarusian State Medical University, Minsk, Belarus
Published: September 2022

Background. One of the perspectives of anticytokine therapy is the development of synthetic oligopeptides, which can bind and inhibit the activity of cytokines. The peptide, which is a structural analogue of the cytokine-binding region of the chemokine receptor, is of interest as a ligand for interaction with interleukin-8 (IL-8). The aim of the research was to evaluate the interaction of the Trp-Asp-Phe-Asp with IL-8. Material and methods. The interaction between the peptide and cytokine was evaluated by the change in the IL-8 concentration, which was assessed by enzyme immunoassay. Oligopeptide was used in free form adsorbed on the bottom of the plate well and immobilized in a polyacrylamide gel at a concentration of 1 µM/ml. Results. The results of the study showed that Trp-Asp-Phe-Asp, both in free and immobilized form, has the ability to bind IL-8. The maximum concentration of IL-8 bound by the free peptide is 22.13 (14.09; 30.17) pM/ml, for the adsorbed peptide – 4.22 (3.69; 4.75) pM/ml. Oligopeptide immobilized in the gel reduces the IL-8 concentration in blood plasma by 25.39 (21.34; 29.44) pM/ml. Conclusions. The results obtained are the basis for the development of medical devices for hemosorption in order to extract IL-8 from human blood plasma.
CLINICS AND DIAGNOSTICS OF CAVERNOUS MALFORMATIONS OF FUNCTIONALLY SIGNIFICANT ZONES OF THE BRAIN
Authors:   Republican Scientific and Practical Centre of Neurology and Neurosurgery, Minsk, Belarus, Rodzich A. V. , Sidorovich R. R. ,   Republican Scientific and Practical Centre of Neurology and Neurosurgery, Minsk, Belarus
Published: September 2022

The aim of the study is to develop an algorithm for diagnosing cavernous malformations (CM) of functionally significant brain localizations. Material and methods. During randomization and exclusion of patients from the general sample (329 patients) 69 patients were included in the study. Patients were divided into study and control groups. Results. Methods of preoperative and intraoperative diagnostic examinations of patients with CM of functionally significant brain localizations, including neurological, neuroimaging (MRI, CT angiography, angiography, functional MRI, MRI tractography), electroencephalography were optimized. Conclusions. The application of the developed algorithm for the complex diagnosis of CM of functionally significant brain localizations allows the neurosurgeon to accurately plan access to the CM and clarify the localization of the CM in relation to functionally important areas of the brain.
COMPUTED TOMOGRAPHY IN DIAGNOSIS OF AORTIC ANEURISM
Authors:   Grodno State Medical University, Grodno, Belarus, Nechiporenko A. S. , Bakhar A. A. ,   Grodno University Clinic, Grodno, Belarus, Rogatsevich A. S. ,   Grodno University Clinic, Grodno, Belarus, Goid V. A. ,   Lida Central District Hospital, Lida, Belarus
Published: September 2022

Background. Computed tomography (CT) is one of the leading methods in the diagnosis of diseases of the aorta and its branches, pulmonary arteries, and heart. Aim. Study and demonstration of the potentials of CT in the diagnosis of aortic diseases and follow-up after treatment. Material and methods. Russian-language and English language literature sources have been studied. Clinical cases of various localizations and sizes of aneurysms of the thoracic and abdominal aorta are presented. Results. The given review presents the issues of etiopathogenesis of aortic aneurysms, reveals the role of CT in the primary assessment of the aorta and control of the treatment. Conclusions. Timely reliable diagnosis of aortic diseases using CT enables to save the life and health of patients, as well as to conduct subsequent monitoring of treatment.
ФОРМИРОВАНИЕ СТУДЕНЧЕСКОГО САМОУПРАВЛЕНИЯ НА ФАКУЛЬТЕТЕ ИНОСТРАННЫХ УЧАЩИХСЯ В ГРОДНЕНСКОМ ГОСУДАРСТВЕННОМ МЕДИЦИНСКОМ УНИВЕРСИТЕТЕ
Authors:   Grodno State Medical University, Grodno, Belarus, Hushchyna L. N. , Stenko A. A. ,   Grodno State Medical University, Grodno, Belarus
Published: September 2022

The article describes the development history of students’ self-governing, its goals, main principles and forms of students’ participation in the arrangement of an academic process as well as social and public activities at the University. The role of Students’ National Unions in the development of students’ self-governing at the Medical Faculty for International Students is underlined. The article provides examples of the structure of the Unions, their governing bodies and forms of activity.
PEMBERIAN MAKANAN PENDAMPING ASI DINITERHADAP KEJADIAN STUNTING PADA BALITA : LITERATURE REVIEW
Authors: Handayani Utari , Fujiana Fitri , Murtilita Murtilita
Published: September 2022

PemberianMPASI terlalu dini merupakan faktor penyebab terjadinya kejadian stunting. Stunting adalah permasalahan gizi kronik pada balita, memiliki status gizi berdasarkan panjang badan/usia dantinggi badan/usia memiliki nilai z-score nya kurang -2 standar deviasi (SD) atau kurang dari -3standar deviasi (SD) dikatagorikan sebagai balita sangat pendek. Tujuan: Menganalisis pemberian MPASI dini terhadap kejadian stunting. Metode: Jenis penelitian mengunakan Literatur Review. Artikel di peroleh menggunakan database dengan penelusuran elektronik pada Google Scolar, Pubmed, Scindirect, dan Portal Garuda yang di publikasikan pada tahun 2016-2020. Hasil: Dari hasil Literature Review 8 artikel yang di analisis di peroleh Makanan Pendamping ASI dini (MPASI) pada balita <6 bulan terdapat hubungan signifikan terhadap kejadian stunting. Makanan pendamping ASI secara langsung jika diberikan sejak dini memiliki resiko stunting daripada balita yang diberi MPASI > 6 bulan. Kesimpulan: Hasil analisis dapat disimpulkan bahwa terdapat keterkaitan pemberian MPASI dini terhadap keadian stunting pada balita. Pemberian MPASI yang kurang tepat pada waktunya dapat mempengaruhi angka kejadian stunting sehingga diperlukan praktik pemberian MPASI secara tepat untuk menurunkan angka kasus stunting.
First steps in the inverse design of porous metal oxide materials: lacunary WellsDawson anion
Authors: Malcolm Daniel , Vilà-Nadal Laia
Published: September 2022

Porous metal oxide materials have been obtained from a ring-shaped macrocyclic polyoxometalate structural building unit, [P8W48O184]40−. This is tungsten oxide building block with an integrated "pore" of 1 nm in diameter that, connected with transition metal linkers, is able to assemble zero to three-dimensional frameworks. Our investigation has been centered in the well-known [P2W18O62]6- Wells-Dawson structure, as well as its lacunary derivatives [P2W12O48]14-. Our aim is to predict new building blocks for ring-shaped porous material, hence we have constructed a few dozen different POMs, largely differing in their heteroatom (X) content, and have determined its electron densities, electronic and reduction/oxidation energies, and HOMO-LUMO gaps, the last of which gives at least tentative information surrounding the frameworks stability.
A Modular and Efficient Synthetic Platform for the Construction of Supramolecular Mono-telechelic Polymers
Authors: Liu Jiaxiong , Huang Fang , Liu Yiliu
Published: September 2022

Supramolecular telechelic polymers are intriguing macromolecular systems for the construction of complex supramolecular systems and responsive soft materials. In this work, we report a practical synthetic approach to preparing supramolecular mono-telechelic polymers with high efficiency and modularity. With a combination of in situ catalyst functionalization, ring- opening metathesis polymerization, and post-polymerization modification, a series of supramolecular mono-telechelic polymers with different supramolecular end-groups and sidechains are synthesized. Several selected examples are then discussed in detail to demonstrate their potential in constructing hierarchical supramolecular architectures, adaptive materials, and supramolecular biomaterials. It is highly anticipated that the synthetic approach reported here will provide rapid and controlled access to complex supramolecular telechelic polymers with tailored functions.
Thermoelectric properties of Zintl arsenide EuCuAs
Authors: Nakamura Naoto , Goto Yosuke , Nakahira Yuki , Miura Akira , Moriyoshi Chikako , Lee Chul-Ho , Usui Hidetomo , Mizuguchi Yoshikazu
Published: September 2022

We demonstrate thermoelectric transport properties of Zintl arsenide EuCuAs. The crystal structure of EuCuAs (hexagonal P63/mmc space group) consists of a covalently-bonded honeycomb-type [CuAs] network sandwiched by Eu2+ ions. Undoped EuCuAs exhibit the thermoelectric power factor of 1.2 and 0.4 mW/mK2 at 673 K along directions perpendicular and parallel to the uniaxial hot-pressing direction, respectively. Despite the relatively high power factor, dimensionless figure of merit is limited to 0.1 at 673 K due to the high lattice thermal conductivity, >2.0 W/mK. In addition to relatively high power factor, first-principles calculations predicted that, owing to a peculiar shape of the Fermi surface, heavy hole doped EuCuAs with hole concentration of >1.5 x 10^21 cm^-3 will exhibit the axis-dependent conduction polarity, which enables us to construct the transverse thermoelectric devices. We investigated the synthesis and thermoelectric transport properties of Eu1-xNaxCuAs using sodium (Na) as a hole dopant, resulting in a hole concentration of 1.0 x 10^21 cm^-3. The absolute value of the Seebeck coefficient decreased by Na-doping, as predicted by first-principles calculations, but no conduction polarity switching was observed. This may have resulted from insufficient hole concentration and/or preferred orientation of the samples.
Tipología de los contenidos virales de desinformación durante los primeros meses de emergencia sanitaria por la COVID-19 en el Perú
Authors: Pichihua Vegas Sofía Pamela
Published: September 2022

Se realiza un análisis de los contenidos de desinformación (N=80) que alcanzaron viralidad tras el anuncio del primer caso de COVID-19 y durante la cuarentena obligatoria por la pandemia (6 de marzo al 30 de junio del 2020), y que fueron identificados por sitios de fact-checking y entidades públicas. El estudio adapta una tipología que incluye cinco tipos de contenidos desinformativos: exageración, descontextualización, engaño, alertas falsas y estafas, destacando sus características principales. De esta manera, la investigación revela que WhatsApp fue el medio digital más usado para la difusión, así como el uso de múltiples redes sociales. Las fotos y texto fueron los elementos más usados para estos contenidos, mientras que las principales temáticas se centraron en la crisis sanitaria, el bono económico para las familias vulnerables, las restricciones en la pandemia, y los mitos de salud. Además, el estudio propone una guía para el proceso de verificación de datos en un contexto de emergencia sanitaria vigente.
Periodismo en contextos de violencia, principales problemas y posibles vías de solución: percepciones de periodistas latinoamericanos
Authors: Tejedor Santiago , Cervi Laura , Tusa Fernanda
Published: September 2022

Un total de 324 periodistas han sido asesinados en el mundo en la última década. Partiendo de ello, el trabajo presenta una investigación a partir de 26 periodistas con una trayectoria de más de 10 años en la cobertura de temas de violencia en diferentes países de la región latinoamericana. El objetivo es analizar la percepción de los periodistas latinoamericanos sobre el ejercicio de la profesión en contextos de conflicto. La propuesta metodológica ha aplicado dos técnicas de investigación: la entrevista en profundidad y el método Delphi. El estudio concluye que los periodistas valoran la conformación de redes, pero cuestionan las alianzas con otro tipo de actores de la sociedad civil; y advierte sobre la situación las mujeres periodistas y la necesidad de renovar los planes de estudio de las escuelas de comunicación.
¿Qué se comenta de un reality? Análisis del foro en Facebook de Gran Hermano España (2011- 2019)
Authors: Cabeza José , Casado Raúl , Paz María Antonia
Published: September 2022

Este artículo analiza el historial completo del foro de Facebook de Gran Hermano España durante el período 2011-2019. En el estudio se obtuvieron más de 1,2 millones de comentarios del grupo de Facebook. Se investiga cuáles son los temas más recurrentes de los que hablan los fans del programa y cuál es su posición ante ellos. Los participantes aceptan la lógica del reality (mecánica y objetivo final), pero a veces cuestionan la imparcialidad de la cadena si aprecian que interviene en la realidad para obtener una ventaja comercial. Sin embargo, pasa inadvertida la censura que ejerce el programa sobre los comentarios de sucesos que puedan dañar su imagen. Los espectadores, mayoritariamente de género femenino, critican tres veces más (2,79) a las mujeres concursantes que a los hombres. Sin embargo, también hay cierta alianza de género entre foristas y concursantes femeninas: se las apoya más a ellas para que ganen.
El rol de la mujer en la ciencia y la docencia en comunicación: análisis a partir de los programas universitarios en España
Authors: García-Jiménez Leonarda , Torrado-Morales Susana , Díaz Tomás Juan Manuel
Published: September 2022

Este artículo analiza el papel de las investigadoras en las ciencias de la comunicación mediante el estudio de su presencia/ausencia en las bibliografías de 108 guías docentes (syllabus) de los grados de periodismo en España durante el curso 2020-2021. El trabajo investiga los roles de la mujer en el campo comunicológico al medir el grado de visibilización de las científicas y sus aportaciones de manera estadística y comparativa a la de los investigadores, cuantificando los patrones de citación de las guías docentes incluidas en función del género de los/as autores/as. Los datos fueron analizados con el software estadístico libre R (versión 4.0.3) y se realizó un análisis descriptivo e inferencial. Los principales resultados en torno a los patrones de citación de la investigación son: 1) una infra-citación de publicaciones de científicas; 2) una sobre-citación de publicaciones de investigadores; y 3) la no existencia de homofilia de género (los investigadores no tienden a citar más personas de su mismo género), puesto que las autoras son poco citadas y esta escasa visibilidad se debe por igual tanto a profesores, como a profesoras. La más referenciada es Elizabeth Noelle-Neumann, una de las pocas “clásicas” presentes, lo que sugiere un efecto Matilda en lo referente al borrado histórico de las aportaciones femeninas. Como conclusión, el artículo aboga por la necesidad de transformar no solamente las prácticas de citación, sino toda una cultura científica que niega a la mujer como fuente de referencia y autoridad desde las primeras etapas de formación universitaria.
Identidad Visual Editorial Dinámica y diseño de portadas: el caso de La Luna de Metrópoli (2018-2020)
Authors: Martín-Sanromán Juan-Ramón , Suárez-Carballo Fernando , Galindo-Rubio Fernando
Published: September 2022

La Identidad Visual Editorial es una rama de la identidad visual que se ocupa de la traducción simbólica de la personalidad de las publicaciones, productos en cuya estrategia adquieren especial protagonismo las portadas como principal escaparate del contenido y factor esencial en la comercialización del medio. Por otro lado, en el branding contemporáneo se observa una notable atención hacia las identidades dinámicas, fenómeno que propone un uso más flexible de los rasgos que configuran sus respectivos programas gráficos. En este contexto, la presente investigación busca analizar las claves de la Identidad Visual Dinámica en el ámbito editorial -Identidad Visual Editorial Dinámica (IVED)- e ilustrar esta estrategia mediante la atención a las cubiertas de La Luna de Metrópoli (un semanario galardonado en múltiples ocasiones por su excelencia visual y creativa) como caso de estudio. Con una muestra de 96 piezas diseñadas entre 2018 y 2020 -año en el que se interrumpe su edición impresa-, se analizan cuatro variables: los cambios en la mancheta, el diseño, los contenidos y el uso de la retórica en las portadas (como textos visuales). Entre sus conclusiones, el artículo revela la importante presencia de las figuras retóricas -y, en especial, de las metáforas- en la identidad de una publicación definida por la mutabilidad de su cabecera y la heterogeneidad estilística de sus cubiertas.
Alejandro Barranquero, A. y Sáez-Baeza, C. R. (Coords.). La comunicación desde abajo. Historia, sentidos y prácticas de la comunicación alternativa en España
Authors: Ferrón Benjamín
Published: September 2022

Coordinado por Alejandro Barranquero, comunicador español, Doctor en Periodismo por la Universidad de Málaga y Profesor e Investigador en el Departamento de Comunicación de la Universidad Carlos III de Madrid, y Chiara Sáez Baeza, socióloga chilena, Doctora en Comunicación y Posdoctorada en Políticas Públicas por la Universidad Autónoma de Barcelona, Profesora Asociada del Instituto de la Comunicación e Imagen de la Universidad de Chile, este volumen colectivo está compuesto de siete capítulos, escritos por una decena de investigadores. Su aporte es triple: empírico, teórico y político.
Cross talk between glucose metabolism and immunosuppression in IFN-γ–primed mesenchymal stem cells
Authors: Yao Mengwei , Chen Zhuo , He Xiao , Long Jiaoyue , Xia Xuewei , Li Zhan , Yang Yu , Ao Luoquan , Xing Wei , Lian Qizhou , Liang Huaping , Xu Xiang
Published: September 2022

The immunosuppressive function “licensed” by IFN-γ is a vital attribute of mesenchymal stem cells (MSCs) widely used in the treatment of inflammatory diseases. However, the mechanism and impact of metabolic reprogramming on MSC immunomodulatory plasticity remain unclear. Here, we explored the mechanism by which glucose metabolism affects the immunomodulatory reprogramming of MSCs “licensed” by IFN-γ. Our data showed that glucose metabolism regulates the immunosuppressive function of human umbilical cord MSCs (hUC-MSCs) challenged by IFN-γ through the Janus kinase–signal transducer and activator of transcription (JAK-STAT) pathway. Furthermore, ATP facilitated the cross talk between glucose metabolism and the JAK-STAT system, which stimulates the phosphorylation of JAK2 and STATs, as well as the expression of indoleamine 2, 3-dioxygenase and programmed cell death-1 ligand. Moreover, ATP synergistically enhanced the therapeutic efficacy of IFN-γ–primed hUC-MSCs against acute pneumonia in mice. These results indicate a novel cross talk between the immunosuppressive function, glucose metabolism, and mitochondrial oxidation and provide a novel targeting strategy to enhance the therapeutic efficacies of hUC-MSCs.
Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments
Authors: Lukac David , Machacova Zuzana , Moudry Pavel
Published: September 2022

DNA synthesis of the leading and lagging strands works independently and cells tolerate single-stranded DNA generated during strand uncoupling if it is protected by RPA molecules. Natural alkaloid emetine is used as a specific inhibitor of lagging strand synthesis, uncoupling leading and lagging strand replication. Here, by analysis of lagging strand synthesis inhibitors, we show that despite emetine completely inhibiting DNA replication: it does not induce the generation of single-stranded DNA and chromatin-bound RPA32 (CB-RPA32). In line with this, emetine does not activate the replication checkpoint nor DNA damage response. Emetine is also an inhibitor of proteosynthesis and ongoing proteosynthesis is essential for the accurate replication of DNA. Mechanistically, we demonstrate that the acute block of proteosynthesis by emetine temporally precedes its effects on DNA replication. Thus, our results are consistent with the hypothesis that emetine affects DNA replication by proteosynthesis inhibition. Emetine and mild POLA1 inhibition prevent S-phase poly(ADP-ribosyl)ation. Collectively, our study reveals that emetine is not a specific lagging strand synthesis inhibitor with implications for its use in molecular biology.
Development of virtual incubation platform for start-ups and college students
Authors: Tusharkushwaha  , Aayushi Mishra , Adarsh Pandey , Vedikamusle  , Ravikantsoni
Published: September 2022

Entrepreneurship in India is evolved through start-ups and funding. For rural Indian students, this is still a dream. The goal of this paper is to create a virtual incubator for rural students in India. It will be an online portal that will provide rural students with the opportunity to share their business concepts, form concepts with the help of mentors, gain product maturity, find suitable funding sources, and provide space for product launches and sales. The product development can be done onsite at the student and the product can be demonstrated through the portal. Portal development uses Next.js, Firestore, Firebase Authentication, Socket IO, Node.js, etc. This document describes the process of developing the necessary programming framework and project management methodologies to implement this portal application. This paper also provides screenshots of the development of the prototype of this web application. This work contributes bright ideas for mentors and investors.
Effect of viscosity on iron encapsulation using alginate as a carrying agent in a
controlled spray drying process
Authors: Permanadewi I. , Kumoro A.C. , Wardhani D.H. , Aryanti N.
Published: September 2022

The encapsulation method is a method that protects Fe from oxidation, increases
bioavailability and reduces the unwanted taste, aroma, and distinctive colour of Fe.
Alginate is used as an encapsulant because it can be regulated in viscosity. The drying
process by spray drying is chosen to obtain the final product that has the appropriate
quality standards. The purpose of this study was to determine the effect of alginate 50
mPas, 100 mPas, 150 mPas, 200 mPas, 250 mPas and 300 mPas viscosity on the
characteristics of powder encapsulation. The results showed that the higher the viscosity,
the darker the colour of the powder produced. Powder particle size increases with
increasing viscosity; and the higher the viscosity, the higher the moisture content. The
solubility of the alginate-Fe encapsulated powder was lower with increasing viscosity. The
particle morphology shows a lot of indentation and unevenness, and the pore size is bigger
at a viscosity of 150 mPas to 300 mPas. The alginate-Fe encapsulated powder of all
viscosity variables showed the same functional groups but in different intensities. At the
testing of Fe2+ levels, it turned out that Fe3+ had higher levels than Fe2+. The process of
releasing Fe2+ at pH 1.2 was slower than pH 6.8. From the research results, alginate-Fe
encapsulation powder with a viscosity of 100 mPas produced the highest performance in
protecting Fe, thus, a good viscosity of the feed solution was recommended in the spray
drying process.
Interior Architecture: An Empathetic Approach.
Authors:   , Greer Taylor
Published: September 2022

This study explores the role of ‘empathy’ in commercial Interior Architecture design. Topics of phenomenology, sensory experience of space, and design representation are analysed to develop a design approach relative to brand identity and local vernacular. This includes key research preoccupations including reinterpretation and adoption of select precedents’ use of style, form, materiality, lighting and colour within an interior, in an attempt to ensure the final design outcome embodies a sense of ‘empathy’.

Each topic is researched through formal experimentation. This includes literature review, digital modelling and drawing. Design outputs are continuously analysed and recorded, framed carefully and clearly utilised.

The result presents a proposal for an interior fit-out for the clothing brand Zambesi, located at 107 Customhouse Quay, Wellington. The design revealed that an empathetic approach to designing a commercial interior ensures a stylistically informed atmosphere that successfully emotionally and physically connects with its inhabitants.

The result establishes that the most important variables within an empathetic approach are attention to the bodily and emotive response to the built environment, purposeful reference to local vernacular, and abstraction or reinterpretation of composition of architectural elements. This asserts the importance of design awareness and sensitivity, critical thinking, design communication and representation towards designing a meaningful space.

In conjunction with this, the outcome inverts our usual modes of spatial understanding and highlights the urgency for solutions to our current disposition of commercial interiors, as they lack any substantial attempt to create meaningful and connective spaces.