bluuebunny/crossref_metadata_2025 huggingface dataset:
Human health risk assessment and spatial distribution of fluoride from shallow groundwater in a region of southwest China
Authors: Zhang Kai , Li Xiaonan , Zheng Xinhui , Qiang Changdi , Zhang Xinghao
Published: October 2020

This article took fluoride in shallow groundwater of a township in southwestern China as the research object. Fifty sampling points were set up in the studied area. The fluoride was tested by the ion-selective electrode method. The health risk model recommended by the United States Environmental Protection Agency was used. Based on the Chinese population, human health risk assessment was performed for fluoride in shallow groundwater in the studied area, and the Kriging interpolation method was used to simulate the spatial distribution of fluoride concentration in the area. The research showed the following. (1) The concentration of fluoride in the shallow groundwater samples in the studied area was 0.06–0.78 mg/L, with an average value of 0.35 mg/L, which was in line with the limit value (1.00 mg/L) in the standards for drinking water quality (GB 5749–2006), but its maximum value was 0.78 mg/L, which was 1.86 times of the background value. (2) The average hazard index of children and adults were 0.27 and 0.15, respectively, which were less than 1, and the risk was at an acceptable level; the noncarcinogenic risk of children was 1.8 times that of adults; the average values of total risk quotient for groundwater fluoride intake by children and adults were 0.27 and 0.15, respectively, and 1.19E-03 and 7.26E-04 by skin, respectively. This indicated that of the two routes, oral intake was the main route of exposure to fluoride. The noncarcinogenic risk values of fluoride in rural and urban areas were similar, and both were less than 1. (3) The high-value areas of fluoride were mainly concentrated in the southeast of the area, which was mainly affected by the superposition of natural factors and industrial park sewage discharge. Through human health risk assessment and spatial distribution of fluoride in regional groundwater, it can provide a theoretical basis for regional groundwater pollution prevention.
A study of land subsidence problems by ALPRIFT for vulnerability indexing and risk indexing and treating subjectivity by strategy at two levels
Authors: Sadeghfam Sina , Nourbakhsh Khiyabani Farhad , Khatibi Rahman , Daneshfaraz Rasoul
Published: October 2020

Land subsidence in response to declining water table at plains under sparse data is investigated using ALPRIFT, introduced recently by the authors at the stage of its proof-of-concept. ALPRIFT is a framework, which pools consensually together seven general-purpose data layers with a scoring system of prescribed rates accounting for local variations and prescribed weights accounting for their relative importance. It is a subsidence vulnerability indexing (SVI) approach, which estimates relative values and is subject to inherent subjectivities. The paper treats the transformation of SVI into a risk indexing (RI) capability through a scheme, in which ALPRIFT breaks down into ALRIF, characterising passive local effects and into water-driven PT, characterising active system-wide effects. The addition of passive and active processes renders total vulnerability but their products render a measure of risk index. A modelling strategy is formulated for SVI and RI at two levels to treat inherent subjectivities and involves data fusion by using catastrophe theory. The strategy is applied to an aquifer subject to decline in water table at the coast of Lake Urmia, with sparse data. The results provide evidence for the proof-of-concept on SVI and RI using ROC/AUC performance metrics.
Using long short-term memory networks for river flow prediction
Authors: Xu Wei , Jiang Yanan , Zhang Xiaoli , Li Yi , Zhang Run , Fu Guangtao
Published: October 2020

Deep learning has made significant advances in methodologies and practical applications in recent years. However, there is a lack of understanding on how the long short-term memory (LSTM) networks perform in river flow prediction. This paper assesses the performance of LSTM networks to understand the impact of network structures and parameters on river flow predictions. Two river basins with different characteristics, i.e., Hun river and Upper Yangtze river basins, are used as case studies for the 10-day average flow predictions and the daily flow predictions, respectively. The use of the fully connected layer with the activation function before the LSTM cell layer can substantially reduce learning efficiency. On the contrary, non-linear transformation following the LSTM cells is required to improve learning efficiency due to the different magnitudes of precipitation and flow. The batch size and the number of LSTM cells are sensitive parameters and should be carefully tuned to achieve a balance between learning efficiency and stability. Compared with several hydrological models, the LSTM network achieves good performance in terms of three evaluation criteria, i.e., coefficient of determination, Nash–Sutcliffe Efficiency and relative error, which demonstrates its powerful capacity in learning non-linear and complex processes in hydrological modelling.
On-site sanitation density and groundwater quality: evidence from remote sensing and in situ observations in the Thiaroye aquifer, Senegal
Authors: Diaw Mor Talla , Cissé-Faye Seynabou , Gaye Cheikh Becaye , Niang Seydou , Pouye Abdoulaye , Campos Luiza C. , Taylor Richard G.
Published: October 2020

In rapidly urbanising low-income towns and cities, there remains an absence of scientific evidence and regulatory structures to sustain the quality and quantity of groundwater used for low-cost water supplies and to reconcile this with continued use of the subsurface for low-cost sanitation. Here, we analyse the relationship between the density of on-site sanitation and shallow groundwater quality in the Thiaroye aquifer of Quaternary sands in Dakar, Senegal. On-site sanitation was mapped using object-oriented classification and visual interpretation of high-resolution, optical satellite images and ground-truthing surveys. Groundwater quality was assessed over a three-year period (2017–2019) from a network of 61 sources comprising boreholes, dug-wells, hand tubewells and piezometers. More than 253,000 on-site sanitation facilities are identified over an area of 520 km2 with densities ranging from 1 to 70 per hectare. A moderate, statistically significant linear relationship (r2 = 0.55, p « 0.01) is found between the density of on-site sanitation facilities and nitrate concentrations in sampled groundwater sources. Groundwater contamination beyond the WHO drinking-water guideline value (50 mg/L) occurs where densities of on-site sanitation facilities exceed 4 (±4) per hectare, a threshold commonly surpassed in peri-urban areas underlain by the Thiaroye aquifer of Dakar.
Rehabilitation and upgrading wastewater treatment plant for safe irrigation reuse in remote area
Authors: Abdel-Shafy Hussein I. , Mansour Mona S. M.
Published: October 2020

This study presents an extensive evaluation of a full-scale sewage treatment system in a remote area with a population of 9,000 equivalents in Egypt. The present achievement can be implemented in several arid and semi-arid areas. Previously, this treatment system was heavily destroyed during the turmoil and became completely out of operation. Presently, the capacity of the treatment system increased from 345.5 to 648 m3/d. The present rehabilitation, upgrading, and optimizing consisted of rebuilding the main construction system, addition of chemical coagulation/sedimentation, Gravel Bed Hydroponic Wetland (GBHW) followed by waste maturation pond at a surface area of 784 m2. Results indicated that the overall removal of the pollution parameters namely: turbidity, total suspended solids (TSS), chemical oxygen demand (COD), Biological oxygen demand (BOD5), and oil and grease were excellent (ranged between 96.9 to 99%). Further improvement was achieved by employing the maturation pond. In addition, successful removal of the nutrients elements in the final treated effluent reached 83.4% for total kjeldahl nitrogen (TKN), 99.3% for ammonia-nitrogen, 63.4% for organic nitrogen, and 59.8% for total phosphorous (TP). The pathogen removal was excellent, namely: faecal coliform and E.coli, where the overall removal reached 100% each (more than ten and six orders of magnitude). Meanwhile, the number of cells or eggs of Nimatoda (count/L) in the raw wastewater was also 100% removed in the final treated effluent.
Air entrainment by inclined circular plunging water jets with various impingement heights
Authors: Ma Yiyi , Zhang Luchen , Yang Yu , Wei Ping
Published: October 2020

This paper presents an experimental study on air entrainment by inclined circular plunging water jets issued from long nozzles with various jet impingement heights up to 6.1 m. Particular attention was paid to the jets having a large impingement height, and which disintegrated into small droplets before reaching the water surface. The dominant sizes and velocities of the droplets generated by jet breakup were 1–4 mm and 4–9 m/s. The results show that for plunging water jets having the same hydraulic head, the air entrainment rate increased as the jet impingement height at first grew, then dropped as the jet impingement height kept increasing. The early increase in the air entrainment rate was due to the growth of jet surface roughness, while the later decrease was caused by the water jet disintegration. The momentum of the plunging jet decreased dramatically due to the reduced mass and the significant energy dissipation through the atmosphere caused by jet disintegration. This led to a much smaller penetration depth and air entrainment rate compared to with a continuous jet.
Establishment of urban waterlogging pre-warning system based on coupling RBF-NARX neural networks
Authors: Wei Ming , She Lin , You Xue-yi
Published: October 2020

The optimal layout of low-impact development (LID) facilities satisfying annual runoff control for low rainfall expectation is not effective under extreme rainfall conditions and urban waterlogging may occur. In order to avoid the losses of urban waterlogging, it is particularly significant to establish a waterlogging early warning system. In this study, based on coupling RBF-NARX neural networks, we establish an early warning system that can predict the whole rainfall process according to the rainfall curve of the first 20 minutes. Using the predicted rainfall process curve as rainfall input to the rainfall-runoff calculation engine, the area at risk of waterlogging can be located. The results indicate that the coupled neural networks perform well in the prediction of the hypothetical verification rainfall process. Under the studied extreme rainfall conditions, the location of 25 flooding areas and flooding duration are well predicted by the early warning system. The maximum of average flooding depth and flooding duration is 16.5 cm and 99 minutes, respectively. By predicting the risk area and the corresponding flooding time, the early warning system is quite effective in avoiding and reducing the losses from waterlogging.
Potential Repurposing of Drugs with Anti-SARS-CoV-2 Activity in Preclinical Trials: A Systematic Review
Authors: Rocha Yasmim Mendes , de Moura Gabriel Acácio , de Oliveira Juliana Ramos , de Figueiredo Nicolete Larissa Deadame , Nicolete Roberto
Published: October 2020

COVID-19 is an emerging outbreak similar to previous pandemics caused by Severe
Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS).
Till date, SARS-CoV-2 infection is still spreading, representing a major threat to public
health, where several control measures are being practiced in order to culminate its spread.
The research and development of new drugs require a lot of funding in addition to being a
slow and costly process. As a result, new techniques have been proposed to streamline this
process. The repositioning or repurposing of drugs represents an attractive strategy, presenting
a promising way to introduce new drugs. Currently, numerous reused drugs are already available
in the market and are in practice. In this review, it was observed that the antiviral drugs
Entricitabine and Tenofovir display potential therapeutic efficacy in preclinical studies.
Therefore, in silico analyses were considered a potential tool for predicting the effectiveness
of drugs, mainly as an effective approach to encourage a complementary in vitro and in vivo
antiviral evaluation.
Desogestrel and Severe Psychiatric Disorders: A Retrospective Analysis of Federal Adverse Event Reporting System and EudraVigilance
Authors: Shah Manan , Kothari Charmy
Published: October 2020

Background:

Several studies have been published which stated that there is some connection
between severe psychiatric disorders and contraceptive drug “desogestrel”. However, nothing
in the summary of product characteristics (SmPC) or patient information leaflets of desogestrel
about anxiety, more severe anxiety leading to panic attacks, or about risks of severe depression
leading to suicidal thoughts or suicide attempts.

Objective:

To examine the safety and risk association between hormonal contraceptive desogestrel
among women with psychiatric disorders using adverse drug reaction database of FDA Adverse
Events Reporting System (FAERS) and EudraVigilance (EV).

Methods:

Individual case safety reports (ICSRs) of only female patients from Jan 1999 to Nov
2019 and Jan 2004 to Nov 2019 were downloaded from FAERS and EV database, respectively. Reports
of drug desogestrel, dienogest, norgestimate, cyproterone acetate and drospirenone were
downloaded. Disproportionality method of data mining was used to calculate the risk association.

Results and Discusion:

The lower limit of 95% CI of PRR is -0.28 and 2.02, PRR is 1.08 and
9.18, ROR is 1.09 (95%CI: 0.74, 1.59) and 9.26 (95% CI: 7.21, 11.89), Chi square value is 1.21
and 433.68, and IC-2SD is -0.27 and 2.60, respectively for data obtained from FAERS and EV.

Conclusion:

From this study, we conclude that there is no new emerging signal for the drug-event
pair studied. Further study and continuous monitoring are required in future to know more about
this drug-event pair association, as severe psychiatric disorders are not yet mentioned or included
in SmPC and patient leaflet of desogestrel.
Preparation and Characterization of A Nanoliposomal Vaccine of pcLACK Candidate Against Cutaneous Leishmaniasis
Authors: Hezarjaribi Hajar Ziaei , Soosaraei Masoud , Fakhar Mahdi , Akhtari Javad , Rafiei Alireza , Jorjani Oghol Niaz
Published: October 2020

Background:

Leishmaniasis is a public health problem and endemic in countries of the tropics and subtropics. An ongoing project with naked LACK (Leishmania homolog of receptors for activated C-kinase) demonstrated that this case of the gene is entirely susceptible to immune response and it does enter the cells effectively. This study aimed at developing a procedure to prepare a type of lipid nanoparticles overloaded with plasmid LACK (pcLACK) for usage as Leishmania major (L. major) nanoliposomal vaccine.

Materials and methods:

The single-gene expression plasmid of pcLACK was encoded in the LACK antigen. Nanoparticles were set up by thin film procedure using cationic lipids 1, 2-Dioleoyl- 3-Trimethylammonium propane (DOTAP), 1, 2-Dioleoyl-snGlycero-3-Phosphoethanolamine (DOPE), and cholesterol in a molar proportion of 2:1:1 molar ratio. Using dynamic light scattering, the particle diameters of empty and loaded lipoplexes were measured in triplicate. The zeta-potential (ζ) was measured with the same instrument using the zeta potential mode as the average of 20 measurements by diluting the particles into a low salt buffer.

Results:

The results of the sustainability studies of Liposome-pcLACK formulation showed that there were no significant physical changes up to the 30th day of stability study at the storage condition of 4°C. However, there were significant changes in the formulation content during storage at 25°C for 30 days (204.2±0.90 at Day 30 compared with 207.2±0.26 nm at Day 0). It was observed that the prepared nanoliposomal formulation had more stability under refrigeration.

Conclusion:

Immunostimulatory cationic lipids bearing a pcLACK encapsulation could serve as an effective delivery system.
An administration on artificial skin for burning patient skin recovery through tissue engineering
Authors: Das Sourav Kumar
Published: October 2020

Background:

Artificial skin has been tried to implement on subject which is damaged by burn effect.In this
research i tried with Silk fibroin as a block biopolymer and which is very high biodegradability and more flexible for cell
culture as being a part of human body.With this artificial skin of SF/Chitosan will help to produce more pores of tissue
engineering which will create a good implantation system.Skin is the longest and most important organ of human
body.Artificial skin is a collagen scaffold that causes skin regeneration in animals such as humans. The innovative
biomaterial silk consists of this collagen.I also tried to introduce collagen consisting of silk nanofibers for human body
linked to burning patients impacted areas via tissue engineering administration.Body comprises of three layers.They are
sometimes called the hypodermis, epidermis, dermis and the fat layer.

Purpose:

An exploration to implement human compatible artificial skin for burned body.

Materials and methods:

At first turned silk fibroin through degumming process as a block biopolymer and then check
oxygen permeability with silk fibroin and chitosan combination.Check mechanical properties and this total experiment done
through tissue engineering and cell culture. Tissue-built skin substitutes may offer a viable helpful choice for the treatment
of patients with skin harms.

Results:

Implementable long term sustainability and high biodegradability artificial skin through cell culture.

Conclusion:

In this research, artificial skin has been developed with chitosan/SF layer based with complete block
biopolymer and i got a significant result which will be compatible for human original skin with high oxygen and water
permeability with cell culture and it is effective and result oriented for burning patient skin recovery and accidental case in
the replacement of skin.

Discussion:

Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans.The novel
biomaterial silk consists of this collagen.In this research work,we tried to implement collagen consisting silk nanofibers for
artificial skin for human body related to burning patients affected areas through tissue engineering administration.
CUSTOMERS’ SATISFACTION FACTORS OF ONLINE TRANSPORTATION SERVICES
Authors: Kurniawan Yoga , Putritama Afrida
Published: October 2020

Abstract: Customers’ Satisfaction Factors of Online Transportation Service. The purpose of this study is to determine the effect of quality of information system, quality of service, perceived security and perceived privacy on customer satisfaction in using online motorcycle transportation. This research is a survey based research with quantitative approach. The populations in this study are all users of Grab online motorcycle transportation services in Special Region of Yogyakarta. Sampling technique in this study used purposive sampling (non-probability sampling) with a total sample of 162 people. The data collection technique used an online questionnaire that has been qualified for validity and reliability. The data analysis method is multiple linear regression analysis methods. The results showed that there is partial positive effect between quality of information system, quality of service, perceived security, and perceived privacy of Grab customers’ satisfaction. The four dependent variable simultanously showed a significant positive effect between customer satisfaction and the independent variable with value number of the coefficient of determination (adjusted R2) is 0,488, the value of the F-test results is 39.412> 2,868312 and significance 0.000. Keywords: Information Systems Quality, Service Quality, Perceived Security, Perceived Privacy, Customer Satisfaction
FAKTOR-FAKTOR YANG MEMPENGARUHI KEBIJAKAN DIVIDEN
Authors: Meidawati Neni , Nurfauziya Ahada , Chasanah Uswatun
Published: October 2020

Abstrak: Faktor-Faktor yang Mempengaruhi Kebijakan Dividen. Investor memerlukan informasi yang dapat mendukung keputusannya untuk melakukan investasi, salah satunya melakukan analisis terhadap faktor yang mempengaruhi keputusan perusahaan dalam melakukan pembagian dividen. Tujuan dari penelitian melakukan analisis terhadap faktor–faktor yang mempengaruhi kebijakan dividen yaitu likuiditas, profitabilitas dan ukuran perusahaan. Populasi yang digunakan dalam penelitian ini adalah perusahaan manufaktur sektor industri makanan dan minuman yang terdaftar di Bursa Efek Indonesia (BEI) pada periode 2015-2017. Sampel penelitian berjumlah 12 perusahaan dengan menggunakan metode purposive sampling. Pengujian hipotesis, dianalisis dengan menggunakan metode regresi berganda. Hasil penelitian menunjukkan bahwa profitabilitas dan ukuran perusahaan berpengaruh positif signifikan terhadap kebijakan dividen, sedangkan likuiditas berpengaruh negatif signifikan. Kata kunci: likuiditas, kebijakan dividen, profitabilitas, ukuran perusahaan
OMSET USAHA DAN SISTEM INFORMASI AKUNTANSI PADA USAHA PEMPEK DI PALEMBANG
Authors: Bernadus Yohanes Andri Putranto
Published: October 2020

Abstrak: Omset Usaha dan Sistem Informasi Akuntansi pada Usaha Pempek di Palembang. Dalam dekade terakhir, Palembang sering menjadi tempat penyelenggaraan kompetisi olahraga tingkat nasional dan internasional. Hal ini berdampak meningkatnya popularitas salah satu makanan khas Palembang yaitu Pempek. Kondisi ini berpengaruh signifikan pada perkembangan usaha pempek di Kota Palembang. Meningkatnya omset usaha memiliki dampak pada meningkatnya kompleksitas pengelolaan transaksi. Berdasarkan fenomena ini, penelitian ini bertujuan menguji secara empiris pengaruh omset usaha terhadap penerapan sistem informasi akuntansi. Penelitian empiris dilakukan dengan menggunakan data dari 100 usaha pempek di Kota Palembang. Data dikumpulkan dengan menggunakan kuesioner. Hasilnya adalah omset usaha berpengaruh signifikan positif terhadap penerapan sistem informasi akuntansi. Temuan ini mendukung teori kontingensi dalam penerapan sistem informasi akuntansi. Semakin besar omset usaha berdampak pada peningkatan kompleksitas pengelolaan transaksi bisnis. Kondisi ini mendorong munculnya kebutuhan pemilik usaha pempek untuk menerapkan sisitem informasi akuntansi. Penelitian ini memiliki implikasi praktik untuk usaha pempek terkait dengan siklus akuntansi apa yang memerlukan penerapan sistem informasi akuntansi baik pada usaha dengan omset yang relatif kecil dan usaha dengan omset yang relatif besar.Kata kunci: omset usaha, sistem informasi akuntansi, dan usaha pempek
Assessment of adult malnutrition with bioelectrical impedance analysis
Authors: Geisler Corinna , Hübers Mark , Müller Manfred
Published: October 2020

The two aims of this study were to evaluate (i) the prevalence of malnutrition based on age, sex and
BMI specific PA and (ii) to determinate what specific body composition characteristics (skeletal
muscle mass and adipose tissue) are related to a low PA.
Disparities in Video and Telephone Visits Among Older Adults During the COVID-19 Pandemic: Cross-Sectional Analysis
Authors: Schifeling Christopher H , Shanbhag Prajakta , Johnson Angene , Atwater Riannon C , Koljack Claire , Parnes Bennett L , Vejar Maria M , Farro Samantha A , Phimphasone-Brady Phoutdavone , Lum Hillary D
Published: October 2020

Background

Telephone and video telemedicine appointments have been a crucial service delivery method during the COVID-19 pandemic for maintaining access to health care without increasing the risk of exposure. Although studies conducted prior to the pandemic have suggested that telemedicine is an acceptable format for older adults, there is a paucity of data on the practical implementation of telemedicine visits. Due to prior lack of reimbursement for telemedicine visits involving nonrural patients, no studies have compared telephone visits to video visits in geriatric primary care.

Objective

This study aimed to determine (1) whether video visits had longer durations, more visit diagnoses, and more advance care planning discussions than telephone visits during the rapid implementation of telemedicine in the COVID-19 pandemic, and (2) whether disparities in visit type existed based on patient characteristics.

Methods

We conducted a retrospective, cross-sectional analysis of patients seen at two geriatric clinics from April 23 to May 22, 2020. Approximately 25% of patients who had telephone and video appointments during this time underwent chart review. We analyzed patient characteristics, visit characteristics, duration of visits, number of visit diagnoses, and the presence of advance care planning discussion in clinical documentation.

Results

Of the 190 appointments reviewed, 47.4% (n=90) were video visits. Compared to telephone appointments, videoconferencing was, on average, 7 minutes longer (mean 37.3 minutes, SD 10 minutes; P<.001) and had, on average, 1.2 more visit diagnoses (mean 5.7, SD 3; P=.001). Video and telephone visits had similar rates of advance care planning. Furthermore, hearing, vision, and cognitive impairment did not result in different rates of video or telephone appointments. Non-White patients, patients who needed interpreter services, and patients who received Medicaid were less likely to have video visits than White patients, patients who did not need an interpreter, and patients who did not receive Medicaid, respectively (P=.003, P=.01, P<.001, respectively).

Conclusions

Although clinicians spent more time on video visits than telephone visits, more than half of this study’s older patients did not use video visits, especially if they were from racial or ethnic minority backgrounds or Medicaid beneficiaries. This potential health care disparity merits greater attention.
Antecedents of Individuals’ Concerns Regarding Hospital Hygiene and Surgery Postponement During the COVID-19 Pandemic: Cross-sectional, Web-Based Survey Study (Preprint)
Authors: Ostermann Thomas , Gampe Julia , Röer Jan Philipp , Radtke Theda
Published: October 2020

BACKGROUND

The COVID-19 pandemic poses a major challenge to people’s everyday lives. In the context of hospitalization, the pandemic is expected to have a strong influence on affective reactions and preventive behaviors. Research is needed to develop evidence-driven strategies for coping with the challenges of the pandemic. Therefore, this survey study investigates the effects that personality traits, risk-taking behaviors, and anxiety have on medical service–related affective reactions and anticipated behaviors during the COVID-19 pandemic.

OBJECTIVE

The aim of this study was to identify key factors that are associated with individuals’ concerns about hygiene in hospitals and the postponement of surgeries.

METHODS

We conducted a cross-sectional, web-based survey of 929 residents in Germany (women: 792/929, 85.3%; age: mean 35.2 years, SD 12.9 years). Hypotheses were tested by conducting a saturated path analysis.

RESULTS

We found that anxiety had a direct effect on people’s concerns about safety (β=−.12, 95% CI −.20 to −.05) and hygiene in hospitals (β=.16, 95% CI .08 to .23). Risk-taking behaviors and personality traits were not associated with concerns about safety and hygiene in hospitals or anticipated behaviors.

CONCLUSIONS

Our findings suggest that distinct interventions and information campaigns are not necessary for individuals with different personality traits or different levels of risk-taking behavior. However, we recommend that health care workers should carefully address anxiety when interacting with patients.
Editorial Note
Authors: Editorial Board  , Vieira Costa Andressa Liegi , Steuer Max
Published: October 2020

This Editorial Note contains a summary of the IAPSS Politikon webinar on 'Research and Education in Times of Pandemic' that focused on elucidation of online qualitative data collection methods and online education via using Massive Open Online Courses (MOOCs). It also announces the acceptance of the journal to ERIH PLUS database for the social sciences and humanities.
Integrating AR and VR in Teacher Education: What Pre-service Teachers Perceive
Authors: Figueroa-Flores Jorge F. , Huffman Lisa
Published: October 2020

Augmented Reality (AR) and Virtual Reality (VR) are two of the most important technologies nowadays. Both had brought significant changes to education. Recognizing that these technologies have become two of the most powerful scaffolds in education is important to better train pre-service teachers with the use of these technologies. By doing so educator preparation programs provide opportunities for their candidates to practice newly learned skills, imagine new ways of thinking and teaching, and build confidence. At the same time is important to gather the pre-service teachers perceptions with the use of both technologies. This paper focuses on a research that sought to determine the perception of pre-service teachers with the use of AR and VR. It found that pre-service teachers believe in the potential of both technologies for the teaching and learning process and at the same time recognize the need to confront the lack of access and digital divide that students might face. It also showcases the need for more training, resources and research of these technologies in teacher education.
Prostanoid receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database
Authors: Breyer Richard M. , Clapp Lucie , Coleman Robert A. , Giembycz Mark , Heinemann Akos , Hills Rebecca , Jones Robert L. , Narumiya Shuh , Norel Xavier , Pettipher Roy , Sugimoto Yukihiko , Uddin Mohib , Woodward David F. , Yao Chengcan
Published: October 2020

Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Prostanoid Receptors [661]) are activated by the endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF2α, PGH2, prostacyclin [PGI2] and thromboxane A2. Differences and similarities between human and rodent prostanoid receptor orthologues, and their specific roles in pathophysiologic conditions are reviewed in [423]. Measurement of the potency of PGI2 and thromboxane A2 is hampered by their instability in physiological salt solution; they are often replaced by cicaprost and U46619, respectively, in receptor characterization studies.
P2X receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database
Authors: Di Virgilio Francesco , Evans Richard J. , Falzoni Simonetta , Fountain Samuel J. , Jarvis Michael F. , Kennedy Charles , Khakh Baljit S. , King Brian F. , Nicke Annette , Pellegatti Patrizia , Peters John A.
Published: October 2020

P2X receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on P2X Receptors [48, 141]) have a trimeric topology [124, 139, 188] with two putative TM domains, gating primarily Na+, K+ and Ca2+, exceptionally Cl-. The Nomenclature Subcommittee has recommended that for P2X receptors, structural criteria should be the initial criteria for nomenclature where possible. X-ray crystallography indicates that functional P2X receptors are trimeric and three agonist molecules are required to bind to a single receptor in order to activate it [139, 93, 101, 170]. Native receptors may occur as either homotrimers (e.g. P2X1 in smooth muscle) or heterotrimers (e.g. P2X2:P2X3 in the nodose ganglion [265], P2X1:P2X5 in mouse cortical astrocytes [155], and P2X2:P2X5 in mouse dorsal root ganglion, spinal cord and mid pons [52, 221]. P2X2, P2X4 and P2X7 receptor activation can also lead to influx of large cationic molecules, such as NMDG, Yo-Pro, ethidium or propidium iodide [200]. The hemi-channel pannexin-1 was initially implicated in the action of P2X7 [201], but not P2X2, receptors [40], but this interpretation is probably misleading. Convincing evidence now supports the view that the activated P2X7 receptor is immediately permeable to large cationic molecules, but influx proceeds at a much slower pace than that of the small cations Na+, K+, and Ca2+ [64].
HRANITELJSTVO KAO PODRŠKA RAZVOJU REZILIJENTNOSTI KOD DECE NA PORODIČNOM SMEŠTAJU
Authors: Tanasijevic Jelena , Borisavljevic Tamara , Jaksic Ivana
Published: October 2020

Savremeni koncept hraniteljstva usmeren je na osnaživanje dece i mladih na porodičnom smeštaju. Kako je reč o deci i mladima čiji je razvoj ugrožen promenama i gubicima koji često imaju odlike traumatskog iskustva, od izuzetnog je značaja razvijati njihove kapacitete za suočavanje i prevladavanje životnih nedaća. Kreiranjem pogodnih uslova u različitim aspektima porodičnog života može se pružiti podrška razvijanju rezilijentnosti kod ove osetljive grupe. Cilj ovog istraživanja bio je da ispita iz kojih domena porodičnog života deca i mladi na hraniteljstvu crpe snagu i podršku. Analizirani su izveštaji hranitelja o 53 dece i mladih osoba o kojima brinu. Prigodni uzorak je činilo 42 hranitelja (o čega 33 žene, a 11 hranitelja srodnika) sa područja Beograda i Valjeva. Utvrđeno je da mladi najviše snage i podrške crpe iz snažnih porodičnih odnosa ispunjenih toplinom, ljubavlju i konkretnim vidovima podrške, kao i obrazovanja koje je redovno, prilagođeno potrebama deteta i odvija se uz saradnju škole i hranitelja. Implikacije ovih nalaza razmatrane su u okviru rada.
DOPRINOS USLUGE DNEVNOG BORAVKA INKLUZIJI DECE I MLADIH SA SMETNJAMA U RAZVOJU U NOVOM PAZARU
Authors: Plavsic Dragana
Published: October 2020

Predmet ovog rada jeste doprinos usluge dnevnog boravka inkluziji dece i mladih sa smetnjama u razvoju u Novom Pazaru. U prvom delu rada prikazujemo položaj dece i mladih sa smetnjama u razvoju, međunarodna dokumenta koja uređuju ova pitanja, nacionalni normativni okvir i uređenje sistema usluga socijalne zaštite. Rezultati istraživanja nam prikazuju organizaciju rada dnevnog boravka, uticaj dnevnog boravka na kvalitet života korisnika i njihovih porodica, faktore koji utiču na kvalitet usluge dnevnog boravka, kao i probleme i poteškoće sa kojima se suočava pružalac usluge.
U ovom kvalitativnom i kvantitativnom istraživanju koristili smo metode ispitivanja, analize sadržaja relevantnih dokumenata, studiju slučaja institucije Dnevnog boravka u Novom Pazaru i statistički metod.
ОСОБЕННОСТИ СОЗДАНИЯ И ПРИМЕНЕНИЯ РАДИАЦИОННО-ОРИЕНТИРОВАННЫХ МОДЕЛЕЙ ПРИ ПРОЕКТИРОВАНИИ ОТКАЗОУСТОЙЧИВЫХ ИЗДЕЛИЙ СВЧ-ДИАПАЗОНА КЛАССА «СИСТЕМА НА КРИСТАЛЛЕ» И «СИСТЕМА В КОРПУСЕ» НА ОСНОВЕ КРЕМНИЯ, КРЕМНИЙ-ГЕРМАНИЯ И АРСЕНИДА ГАЛЛИЯ
Authors: Елесин В.В. , Сотсков Д.И. , Усачев Н.А. , Кузнецов А.Г.
Published: October 2020

Рассмотрены особенности создания и применения радиационно-ориентированных моделей (РОМ) при проектировании отказоустойчивых изделий СВЧ-диапазона класса СнК и СвК. Представлены примеры РОМ для техпроцессов, применяемых отечественными ДЦ.
ОТЛАДКА И АНАЛИЗ УСТРОЙСТВ И ПРИЛОЖЕНИЙ С ОПЕРАЦИОННОЙ СИСТЕМОЙ НА БАЗЕ LINUX В ЭМУЛЯТОРЕ KOPYCAT
Authors: Гладких А.А. , Кемурджиан А.Л. , Комахин М.О.
Published: October 2020

Рассмотрена разработка модуля для программного обеспечения Kopycat, позволяющего проводить эмуляцию самой операционной системы. Приведены общие сведения по разработанному модулю и его подсистемам.
РАЗРАБОТКА СПОСОБА УЧЕТА ОСОБЕННОСТЕЙ ВАХ ТРАНЗИСТОРА, РАБОТАЮЩЕГО В ПЕРЕХОДНОМ РЕЖИМЕ ОТ PDSOI/FDSOI В КОМПАКТНОЙ МОДЕЛИ
Authors: Шипицин Д.С. , Потупчик А.Г. , Шемякин А.В. , Яшин Г.А.
Published: October 2020

Исследованы и разработаны дополнения к оригинальной модели КНИ КМОП-транзисторов BSIMSOI4.5, учитывающие эффекты изменения подвижности носителей в канале и уменьшения паразитного сопротивления при ненулевом смещении на подложке КНИ-транзистора, который работает в переходном режиме.
МОДЕЛИРОВАНИЕ ЭЛЕМЕНТОВ КРИТИЧНОЙ РАДИОЭЛЕКТРОННОЙ АППАРАТУРЫ: НОВЫЕ ПОДХОДЫ, МОДЕЛИ И АЛГОРИТМЫ, ИХ РЕАЛИЗАЦИЯ И ПРИМЕНЕНИЕ
Authors: Газизов Т.Р. , Заболоцкий А.М. , Куксенко С.П. , Комнатнов М.Е. , Суровцев Р.С.
Published: October 2020

Описаны новые модели, алгоритмы и подходы для вычисления матриц L, C, R, G, откликов и уровня излучаемых эмиссий произвольных многопроводных структур, оценки эффективности экранирования корпусов и решения последовательности СЛАУ. Приведены примеры анализа и оптимизации новых элементов РЭА.
АНАЛИЗ СХЕМ С КОЛЕБАТЕЛЬНЫМИ РЕЖИМАМИ С ИСПОЛЬЗОВАНИЕМ ОДНОШАГОВЫХ МЕТОДОВ ИНТЕГРИРОВАНИЯ ВЫСОКОГО ПОРЯДКА ТОЧНОСТИ
Authors: Гурарий М.М. , Жаров М.М. , Русаков С.Г. , Ульянов С.Л.
Published: October 2020

В работе предлагается алгоритм продолжения огибающих для анализа переходного процесса и установившегося периодического режима аналоговых интегральных схем. Для интегрирования уравнений огибающей с переменным шагом и порядком используются традиционные методы. Для интегрирования системы уравнений схемы на одном периоде предлагается использовать методы интегрирования порядка 1-4, полученные с помощью формулы Обрешкова. Приведены примеры анализа переходного процесса и периодического установившегося режима.
МАРШРУТ ФУНКЦИОНАЛЬНОЙ ВЕРИФИКАЦИИ С ИСПОЛЬЗОВАНИЕМ МАТЕМАТИЧЕСКОЙ МОДЕЛИ АНАЛОГОВЫХ БЛОКОВ НА ЯЗЫКЕ PYTHON НА ПРИМЕРЕ АЦП ПОСЛЕДОВАТЕЛЬНОГО ПРИБЛИЖЕНИЯ
Authors: Липатов И.А. , Скрипниченко М.Н.
Published: October 2020

В статье описан разработанный маршрут смешанного моделирования АЦП последовательного приближения с цифровой частью на языке SystemVerilog и моделью аналоговой части на языке Python. В аналоговой части описывается изменение напряжения на входе компаратора в зависимости от переключения ключей матрицы конденсаторов. Приведены преимущества разработанного подхода и компоненты процесса верификации.
МАЛОГАБАРИТНЫЕ МОЩНЫЕ ПРИЕМОПЕРЕДАЮЩИЕ МОДУЛИ Х-ДИАПАЗОНА ДЛЯ АФАР
Authors: Панасенко П.В. , Волосов А.В. , Ионов А.С. , Красников Г.Я. , Петров А.В.
Published: October 2020

Рассмотрены разработанные приемопередающие модули для АФАР трех модификаций - в герметичном и негерметичном корпусах, а также в бескорпусном исполнении. Приведены их характеристики и результаты исследований параметров в диапазоне рабочих температур от минус 60 °C до 85 °C.
АКТУАЛЬНЫЕ РАЗРАБОТКИ АО «ПКК МИЛАНДР» В ОБЛАСТИ СВЧ-И СИЛОВЫХ ТРАНЗИСТОРОВ НА ОСНОВЕ ШИРОКОЗОННЫХ ПОЛУПРОВОДНИКОВ
Authors: Колесников Д.В. , Тарасов С.В. , Ткачев А.Ю.
Published: October 2020

Рассмотрен современный уровень развития приборов на основе широкозонных материалов группы А3В5, их преимущества и особенности. Представлены уникальные разработки СВЧ GaN HEMT для широкого диапазона частот, а также силовые транзисторы и их характеристики.
IbM BAGI PEMILIK USAHA BAKERY di KOTA MALANG JAWA TIMUR
Authors: Widagdo Bambang , Arifin Zainal , Cantika Yuli Sri Budi
Published: October 2020

Mitra dari kegiatan Program Kemitraan Masyarakat (PKM) ini adalah pemilik usaha bakery di Malang Raya, yaitu Mery Bakery. Usaha Roti “Mery Bakery” yang beralamatkan di JL.L.A Sucipto Kecamatan Blimbing Kota Malang ini adalah milik ibu Menik. Berdasarkan analisis SWOT dilakukan, terdapat dua permasalahan utama, yaitu pemilik usaha bakery tersebut belum mempunyai media promosi online atau berbasis teknologi informasi dengan menggunakan media sosial misalnya blog atau instagram, karena masih menggunakan promosi penjualan langsung dan dari mulut ke mulut pada masyarakat sekitar saja. Padahal peluang meningkatkan penjualan dapat dilakukan dengan menggunakan media promosi online yang mudah, murah dan memiliki daya jangkauan pemasaran yang lebih luas, sehingga bisa mengembangkan pasar tidak hanya di wilayah sekitar saja, tetapi dapat memasarkan produksi bakery-nya ke seluruh wilayah Malang Raya melalui pemesanan online atau COD (cash on delivery). Selain permasalahan pemasaran, permasalahan kedua adalah peningkatan proses produksi terutama pembuatan varian rasa baru untuk roti, misalnya rasa abon sapi, sosis, telo ungu, selai apel, bawang bombay dan lainnya.Solusi yang ditawarkan untuk mengatasi permasalahan pemasaran, adalah pelatihan dan pendampingan pada ibu Menik tentang strategi pemasaran berbasis media sosial yang sesuai dengan karakteristik usaha bakery dan pelatihan yang dilakukan harus dapat digunakan secara berkelanjutan. Pelatihan meliputi peningkatan pengetahuan dan keterampilan tentang strategi pemasaran produk dan pemasaran berbasis teknologi informasi .
Culto Evangélico: Identificación, localización y caracterización en la segunda franja residencial (SFR) de Río Gallegos
Authors: Huenchor Federico , Norambuena Mónica , Cáceres Alicia
Published: October 2020

El presente Informe Científico-Técnico, perteneciente a una Beca de Investigación para Alumnos Avanzados de la UNPA, se enmarca en el PI 29 A/427-1 “La Geografía de las Religiones en el ejido municipal de Río Gallegos en el año 2018. La Geografía Cultural en la Patagonia austral extraandina”. Teóricamente, pertenece a la Geografía Cultural Renovada en general y en particular a la Geografía de las Religiones, históricamente estudiadas desde la descripción y en sus características más básicas; actualmente se estudian integradas al territorio y sus transformaciones a diferentes escalas. Son escasas las investigaciones relacionadas a Río Gallegos, por esto la beca tiene como objetivos, en primer lugar, relevar y analizar bibliografía específica sobre la Geografía Cultural y la Geografía de las Religiones en particular. El segundo, identificar, caracterizar y cartografiar manifestaciones culturales religiosas relacionadas al culto evangélico en la Segunda Franja Residencial de Río Gallegos. Metodológicamente, se relevó, leyó comprensivamente y analizó bibliografía específica; se realizó una salida de campo para identificar y localizar las manifestaciones culturales religiosas evangélicas en la SFR, que fueron representadas cartográficamente con la ayuda de un SIG como herramienta principal y se realizó cartografía temática con dicho programa. Los resultados permitiran caracterizar las manifestaciones culturales, según las denominaciones de las iglesias evangélicas, además de aportar teórica y metodológicamente al PI 29 A/427-1 y a la formación en investigación del becario.
La literatura infantil argentina, de los años ’60 y ’70 al presente: resistencia y continuidad literaria
Authors: Pac Andrea , Cejas Ana
Published: October 2020

La dictadura militar que gobernó el destino de la Argentina en el período 1976-1983 extendió su presencia a múltiples ámbitos de la vida. Las políticas educativas represivas fueron complementadas con la censura directa de textos de literatura infantil. Los temas y la “excesiva imaginación” se consideraron una amenaza para la formación de niños y niñas, y para el orden social que la dictadura perseguía. Paradójicamente, muchos de los mismos textos y escritores prohibidos en aquel momento, son recomendados por el Plan Lector del Ministerio de Educación de la Nación desde el año 2009.Este informe se propone trazar un arco histórico y literario desde las razones de la censura a las razones del rescate de algunos de los textos de literatura infantil prohibidos durante la dictadura 1976-1983. Desde el punto de vista histórico, expone la situación de la literatura infantil a inicios de la década del „70, los principales acontecimientos de censura de la literatura infantil, y los documentos relevantes de ese periodo relacionados con la educación y la producción literaria. Desde el punto de vista de la literatura, indaga en las nociones de infancia y de literatura infantil y las pone en diálogo. A la luz de este diálogo, se desarrolla un análisis de algunos textos de literatura infantil prohibidos. Esto permite elaborar una interpretación de las distintas actitudes de los gobiernos con respecto a esas obras, y subrayar el valor literario y educativo que en la actualidad se reconoce en ellas.
Application of a computer algebra systems to the calculation of the \(\pi\pi\)-scattering amplitude
Authors: Kalinovsky Yuriy L. , Friesen Alexandra V. , Rogozhina Elizaveta D. , Golyatkina Lyubov’ I.
Published: October 2020

The aim of this work is to develop a set of programs for calculation the scattering amplitudes of the elementary particles, as well as automating the calculation of amplitudes using the appropriate computer algebra systems (Mathematica, Form, Cadabra). The paper considers the process of pion-pion scattering in the framework of the effective Nambu-Iona-Lasinio model with two quark flavours. The Package-X for Mathematica is used to calculate the scattering amplitude (starting with the calculation of Feynman diagrams and ending with the calculation of Feynman integrals in the one-loop approximation). The loop integrals are calculated in general kinematics in Package-X using the Feynman parametrization technique. A simple check of the program is made: for the case with zero temperature, the scattering lengths \(a_0 = 0.147\) and \(a_2 = -0.0475\) are calculated and the total cross section is constructed. The results are compared with other models as well as with experimental data.
Asymptotic method for constructing a model of adiabatic guided modes of smoothly irregular integrated optical waveguides
Authors: Sevastianov Anton L.
Published: October 2020

The paper considers a class of smoothly irregular integrated optical multilayer waveguides, whose properties determine the characteristic features of guided propagation of monochromatic polarized light. An asymptotic approach to the description of such electromagnetic radiation is proposed, in which the solutions of Maxwells equations are expressed in terms of the solutions of a system of four ordinary differential equations and two algebraic equations for six components of the electromagnetic field in the zero approximation. The gradient of the phase front of the adiabatic guided mode satisfies the eikonal equation with respect to the effective refractive index of the waveguide for the given mode.The multilayer structure of waveguides allows one more stage of reducing the model to a homogeneous system of linear algebraic equations, the nontrivial solvability condition of which specifies the relationship between the gradient of the radiation phase front and the gradients of interfaces between thin homogeneous layers.In the final part of the work, eigenvalue and eigenvector problems (differential and algebraic), describing adiabatic guided modes are formulated. The formulation of the problem of describing the single-mode propagation of adiabatic guided modes is also given, emphasizing the adiabatic nature of the described approximate solution of Maxwells equations.
Kuryshkin-Wodkiewicz quantum measurement model for alkaline metal atoms
Authors: Zorin Alexander V.
Published: October 2020

The constructive form of the Kuryshkin-Wodkiewicz model of quantum measurements was earlier developed in detail for the quantum Kepler problem. For more complex quantum objects, such a construction is unknown. At the same time, the standard (non-constructive) model of Holevo-Helstrom quantum measurements is suitable for any quantum object. In this work, the constructive model of quantum measurements is generalized to a wider class of quantum objects, i.e., the optical spectrum of atoms and ions with one valence electron. The analysis is based on experimental data on the energy ordering of electrons in an atom according to the Klechkovsky-Madelung rule and on the substantiation of a single-particle potential model for describing the energy spectrum of optical electrons in alkali metal atoms. A representation of the perturbation of a single-particle potential in the form of a convolution of the potential of an electron in a hydrogen atom with the Wigner function of a certain effective state of the core in an alkali metal atom representation allows reducing all calculation algorithms for alkali metals to the corresponding algorithms for the hydrogen atom.