bluuebunny/crossref_metadata_2025 huggingface dataset:
Family genetic screening in rare hereditary diseases
Authors: Kutsev S.I. , Moiseev S.
Published: December 2021

Family genetic testing of probands with newly diagnosed rare hereditary diseases including Fabry disease improves early diagnosis and allows to initiate specific treatment, if available, at earlier stage in affected family members. Diagnosis of Fabry disease, an X-linked lysosomal storage disorder affecting kidneys, heart, brain and other organs, is usually late due to low awareness of physicians about rare diseases. Moreover, early symptoms can be non-specific (e.g. gastrointestinal disorders and autonomic neuropathy) or misleading (e.g. recurrent unexplained fever) whereas characteristic skin rash and keratopathy (cornea verticillata) are frequently overlooked. Undiagnosed patients with Fabry disease can be detected by screening in at-risk populations, such as patients with end-stage renal disease undergoing dialysis or renal transplantation, patients with unexplained left ventricular hypertrophy, and young adults with a history of stroke or transient ischemic attack who have a higher prevalence of the disease compared to general population. High-risk screening paves the way to family screening to identify affected relatives, including children, who can benefit from earlier treatment and genetic counselling. The major barriers to family screening include costs of testing, cultural and societal issues, stigma associated with a diagnosis of genetic disease, low contacts in the family, weak infrastructure, national regulations.
БЕРЕГОЗАХИСНА СПОРУДА
Authors: Мироненко І.М. , Литвиненко В.В.
Published: December 2021

Портові огороджувальні споруди: моли та хвилеломи, піддаються впливу природних явищ, що відбуваються у земній, водній (морській) та повітряній сферах. До дії природних явищ приєднується і вплив факторів, що виникають внаслідок діяльності людини. Ці фактори можуть поділятися на такі основні групи: геологічні; гідрометеорологічні; експлуатаційні; фактори виконання робіт; сейсмічні; військові. Практика будівництва та експлуатації портових огороджувальних споруд свідчить, що за певних випадків фактори кожної з перелічених груп можуть стати причиною деформації споруди. Однак узагальнений аналіз матеріалів про пошкодження огороджувальних споруд дозволяє констатувати, що в більшості випадків вирішальними для їх збереження є геологічні фактори, що зумовлюють характер взаємодії фундаменту споруди та ґрунту, а також визначають стан загальної стійкості споруди і ґрунтового масиву, на якому вона зведена . Портові огороджувальні споруди, піддаючись впливу досить значних вертикальних і горизонтальних сил, створюють інтенсивні та великі за площею навантаження на ґрунти, на яких розташовані. Високе значення напруги ґрунту характерне для молів і хвилеломів гравітаційного типу, що передають навантаження на ґрунт безпосередньо або через підсипку. Найчастіше поверхневі шари морського дна, які є несучими для цих споруд, складаються з неоднорідних і легко стисливих ґрунтів. Тому геологічні фактори мають першорядне значення в проєктуванні і будівництві огороджувальних споруд. Деформації та аварії споруд через невідповідність проєкту або методів виробництва геологічним умовам трапляються дуже часто. Причиною такої невідповідності зазвичай є неправильне уявлення про явища, що відбуваються в ґрунті під навантаженням, а отже, застосування неправильних розрахункових схем і методів визначення взаємодії споруди і ґрунту, що лежить в її основі. Іноді це зумовлено незадовільним проведенням геологічних вишукувань.
Microalgae potential in the capture of CO2 emission
Authors: Frongia Francesca , Arru Laura , Cramarossa Maria Rita , Forti Luca
Published: December 2021

In a perspective projected to reduce the atmospheric concentration of greenhouse gases, in which carbon dioxide is the master, the use of microalgae is an effective and decisive response. The review describes the bio circularity of the process of abatement of carbon dioxide through biofixation in algal biomass, highlighting the potential of its reuse in the production of high value-added products.
Factors contributing and promoting Open Innovation in Indian female-owned Food Processing SMEs- Prioritizing through the AHP technique
Authors: Sahdev Supriya Lamba , Singh Gurinder , Kaur Navleen
Published: December 2021

The prime motivation behind this investigation is to recognize and organize the different factors connected to Open Innovation in the already up and running from last five years Indian female owned SMEs in Food Processing Industry. Fifteen Indian female owners were chosen. An AHP system was utilized to examine the weight of basic elements leading towards Open Innovation. All things considered, the respondents organized advancement technique, opportunity acknowledgment, money and inspiration as the principle criteria that leads to Open Innovation in Indian females owned SMEs in Food Processing. COVID-19, gender gap, raising inner and outer funds were likewise observed as a hindrance ladies face that usually would keep them away from innovative tasks performed for business. The result of this examination is giving policymakers in India food for thought regarding the significance of the factors connected to development of Indian female owned SMEs in Food Processing Industry and will be able to move towards sustainable development goals- Goal 9 (Industry, Innovation and Infrastructure) and Goal 5 (gender equality) which is required for the economic development of the country. This will assist them with systemizing and organizing the basic, advancement of open innovation factors in Indian female owned Food Processing SMEs, which will give a boost to the contribution of Indian females in the financial development of India, which a developing country currently.
Physio-mechanical & wear performance of banana fiber/walnut powder based epoxy composites
Authors: Gairola Surya P , Tyagi Yogesh , Gangil Brijesh , Jha Kanishk
Published: December 2021

The present environmental condition indicates the immediate need for sustainable materials containing mainly natural elements for composite fabrication. Encouragement of natural fibers in composite materials can significantly reduce the greenhouse effect and the high cost of manufacturing synthetic fiber-based polymer composites. Hence, this study aimed to investigate the physio-mechanical properties of banana fiber (BF) fiber -based epoxy (EP) composites filled with walnut shell powder (WNP). Fabrication was carried out by mixing and cold pressing with fixed BF proportion and varying percentages of WNP (0%, 5%, 10%, 15 wt. %). The results obtained in the study suggest the mechanical properties of the BF/EP composite were enhanced with the addition of WNP as a filler. This is because the WNP filler occupies the spaces in the composite, which bridge the gaps between the banana fibers and the epoxy matrix; also, the inclusion of walnut powder in the BF/EP composites greatly enhanced their wear resistance. The microstructural properties of the composites were examined by scanning electron microscopy (SEM).
Implementation of the Policy of Poverty Alleviation Acceleration Program in Bokat District, Buol Regency, Central Sulawesi Province, Indonesia
Authors: Tonggil Ikhlasiani T. , Igirisa Irawati , Tahir Arifin
Published: December 2021

The purpose of this study is to explore the implementation of the poverty alleviation acceleration program policy through the regional government's leading programs, especially maize commodity, in Bokat District, Buol Regency.  It relied on a qualitative descriptive approach by revealing the phenomenon encountered by the farmers who received assistance in several villages, Bokat District. Data collection techniques involved interviews with several informants, continuous observations, and documents related to the poverty alleviation policy in Buol Regency. Further, data analysis was performed by data reduction and presentation, along with conclusion drawing. The results show that the policy has been implemented according to the predetermined stages through Regional Regulation Number 7 of 2015, including community outreach, business capital strengthening, empowerment, monitoring, and evaluation. However, it is found out that the policy is yet to be optimal. The community outreach conducted by the government has not been effective since only a few people took part. This stage also provides business capital strengthening by giving them processing fees, seeds, fertilizers, and pesticides. Still, both stages are only carried out in the first year at each location where the poverty alleviation acceleration program is promoted. In addition, an empowerment program that can support the development of maize commodity as the regional government's leading program has not been executed. Monitoring and evaluation of such a policy have not been entirely performed, impacting different levels of success each village reaches. On this ground, the poverty alleviation acceleration program policy needs to be re-evaluated to also detect any problems in the area, increase people's income, and bring success to the policy implementation.
UTILIZATION OF MACHINE TECHNOLOGY IN INCREASING INSTANT GRINGER PRODUCTION
Authors: Asnawi  , Fransyaigu Ronald , Hanafiah  , Kiswanto Kenedi Ary , Suheri
Published: December 2021

The ginger industry in East Aceh district is widely developed through home industries which are an important part of small and medium industries. This industry is mostly done by housewives on the sidelines of their busy household. The "Halia Instans" industry is one of the small businesses that develops processed ginger products. The raw materials for Instant Ginger will be processed through the following production process, first the ginger is washed clean or the soil is gone, then drained for a few seconds, then the ginger is blended, then after blending the finely ground ginger is squeezed using a machine and processed or cooked with an existing recipe so that produce ginger extract.. the results of the implementation of activities Encourage partners to cooperate with related parties in order to increase the production and marketing of Instant Ginger and add facilities to help increase ginger commodities in the overseas safe area
PENGARUH APLIKASI TRIPLE SUPER PHOSPHATE (TSP) DALAM MENINGKATKAN PRODUKSI TANAMAN KACANG PANJANG (Vigna sinensis L.)
Authors: Ramli Nursayuti
Published: December 2021

Penelitian ini bertujuan untuk mengetahui pengaruh aplikasi pupuk Triple Super Phosphate (TSP) dalam meningkatkan hasil tanaman kacang panjang. Penelitian ini dilaksanakan di Gampong Alue Kupula Kecamatan Peusangan Siblah Krueng Kabupaten Bireuen dengan ketinggian tempat 560 mdpl  yang dimulai pada tanggal 03  Juli sampai dengan tanggal 25 September 2019. Rancangan percobaan yang dilakukan dalam penelitian ini adalah Rancangan Acak Kelompok (RAK) Non faktorial dengan perlakuan. sebagai berikut : Pupuk TSP  (T) terdiri dari 3 taraf perlakuan yaitu : T0 = 0 g/tanaman (kontrol), T1 = 0,6 g/tanaman, dan T2 = 1,20 g/tanaman. Pengamatan yang diamati dalam penelitian ini meliputi tinggi tanaman, Jumlah Polong, jumlah polong pertandan, panjang polong, berat polong, berat 100 biji dan  produktivitas (Ton/Ha). Hasil penelitian menunjukkan pemberian pupuk TSP berpengaruh sangat nyata terhadap pertumbuhan tinggi tanaman umur 20, 40 dan 60 HST, jumlah polong, jumlah polong per tandan, panjang polong dan berat 100 biji tanaman kacang panjang. Perlakuan terbaik dijumpai pada perlakuan pupuk TSP dengan dosis 1,20 g/tanaman (T2).
Analiza ramowa w badaniu rozgrywki narracyjno-interpretacyjnej – dzienniki o zabójstwie Marka Rosiaka
Authors: Olczyk Tomasz
Published: December 2021

Cel: opis mechanizmów ramowania, identyfikacja konkurujących ram i pomiar wyników rozgrywki narracyjno-interpretacyjnej (framing contest) na przykładzie ramowania ataku na biuro poselskie Prawa i Sprawiedliwości 19 października 2010 roku. Metody badań: interpretatywna strategia analizy ramowania polegająca na indukcyjnej, jakościowej rekonstrukcji ram z wykorzystaniem homeostatycznego modelu narracji. Przeanalizowano lokalizację ram w strukturze analizowanych tekstów i związane z nią zabiegi metakomunikacyjne (przeramowujące). Obliczono relatywną ekspozycję ram, a także jednorodność (homogeniczność) i przechylenie ramowania z wykorzystaniem wskaźnika koncentracji Herfindahla-Hirschmanna i na tej podstawie stworzono mapę wyników rozgrywki interpretacyjnej. Badaniu z zastosowaniem oprogramowania do analizy danych jakościowych MaxQDA12 poddano artykuły informacyjne czterech wiodących dzienników opublikowane w dzień po relacjonowanym incydencie. Wyniki i wnioski: analizowana rozgrywka interpretacyjna była silnie spolaryzowana. W badanym przypadku zidentyfikowano tylko dwie dominujące i jedną marginalną ramę. W artykułach informacyjnych występowała znacząca jednostronność i tendencyjność ramowania przejawiająca się wysokimi wartościami wskaźników homogeniczności i przechylenia ramowania. Tylko jeden z czterech dzienników eksponował konkurujące ramy w zbalansowany sposób. Dzienniki stosowały dwie wzorcowe strategie forsowania wybranej ramy: otwartą stronniczość („Nasz Dziennik”) i subtelną metakomunikacyjność („Gazeta Wyborcza”). Oryginalność i wartość poznawcza: zaproponowana konceptualizacja ramowania przywraca pojęciu narracyjne i metakomunikacyjne pierwiastki. Przyjęta strategia indukcyjnej rekonstrukcji ram unika powszechnego w analizie ramowej problemu niejasnego związku między ramami a materiałem empirycznym. Badanie realizuje postulat zwiększenia szczegółowości analizy ramowej poprzez redukcję jednostki kodowania do zdania. Tekst proponuje narzędzia precyzyjnego pomiaru ekspozycji ram i wizualnego mapowania rozgrywki interpretacyjnej i tendencyjności ramowania.
EXAMINATION OF PRE-SERVICE SCIENCE TEACHERS’ UNDERSTANDING LEVELS OF KEPLER’S LAWS WITH RANKING TASK QUESTIONS
Authors: Çobanoğlu Aktan Derya , Oğuzhan Dinçer Emrah
Published: December 2021

The purpose of this study was to investigate pre-service science teachers’ understanding levels of Kepler’s second and third laws. The participants of the study were 38 pre-service science teachers who attended introductory astronomy class in their teacher education program. The participants’ understandings of Kepler’s laws were examined by their answers to ranking tasks, which required participants to rank the situations given in the question, and then to explain the reasons behind their answers. The findings showed that the participants’ understanding levels ranged from partial understanding with alternative conceptions to sound understanding. Moreover the number of the participants with partial understanding with alternative conceptions exceeded the participants with sound understanding. The participants’ explanations to ranking tasks also indicated that although participants knew the classic statements of Kepler’s laws, they had also alternative conceptions. Five different alternative conceptions were identified from the participants’ explanations. Two of them have not been reported in previous studies.
Key words: Kepler’s laws, pre-service science teachers, ranking tasks, understanding levels.
Programa institucional de bolsa de iniciação à docência (Pibid 2018-2020): expectativas, contribuições e desafios do subprojeto biologia UTFPR na percepção dos pibidianos
Authors: Schneider Eduarda Maria , Damke Anderleia Sotoriva
Published: December 2021

Resumo: Este artigo tem como objetivo debater as percepções dos pibidianos acerca das contribuições e desafios do subprojeto PIBID Biologia UTFPR 2018-2020. A pesquisa de cunho qualitativo foi realizada a partir da análise de um questionário aplicado ao final do projeto. A investigação constatou que a participação no projeto atendeu às expectativas de vivenciar a realidade da futura profissão, adquirir fundamentação da prática docente e ter apoio financeiro. Dentre as contribuições, foram destacados a importância da vivência nas escolas, o conhecimento didático e a diminuição dos medos e inseguranças para atuar profissionalmente. Em relação aos desafios que vivenciaram no PIBID, apontaram a inserção no ambiente escolar, o relacionamento com os supervisores e as dificuldades que sentiram para se comunicar e se expressar em sala de aula. Perante tais resultados, consideramos que a participação no PIBID promove experiência no processo formativo, fundamentada na reflexão e problematização de situações reais da profissão docente.Palavras-chave: PIBID; Formação Docente; Biologia; Escola. Institutional program for teaching initiation (Pibid 2018-2020): expectations, contributions and challenges of the subproject biologia UTFPR in the perception of pibidiansAbstract: This article aims to debate the perceptions of pibidians about the contributions and challenges of the subproject PIBID Biology UTFPR 2018-2020. The qualitative nature research was carried out from the analysis of a quiz applied at the end of the project. The investigation found that participation in the project met the expectations of experiencing the reality of the future profession, to acquire reasoning for teaching practice and having financial support. Among the contributions, it was highlighted the importance of living in schools, didactic knowledge and the reduction of fears and insecurities to act professionally. In relation to the challenges they experienced at PIBID, it was pointed the insertion in the school environment, the relationship with supervisors and the difficulties they felt to communicate and express in the classroom. With these results, it is considered that the participation in PIBID promotes experience in the formative process, based on the reflection and problematization of real situations of the teaching profession.Keywords: PIBID; Teacher Education; Biology; School.
Atividades de divulgação científica sobre exoplanetas
Authors: Montemor Ryan Nepomuceno , Teixceira Ricardo Roberto Plaza
Published: December 2021

Resumo: Este trabalho investigou os resultados e impactos de atividades de divulgação científica sobre a ciência dos exoplanetas, ocorridas em 2018, junto a alunos de quatro escolas de educação básica situadas em municípios do litoral norte paulista. Essas ações permitiram que os alunos adquirissem melhor compreensão acerca dos conceitos apresentados sobre exoplanetas e procuraram incentivar o aprofundamento no estudo de áreas da astronomia. Para a elaboração das apresentações estudou-se tanto o estado atual dos conhecimentos científicos sobre exoplanetas, quanto o modo como o trabalho didático com temas de astronomia pode ser efetuado a alunos dos ensinos fundamental e médio. Nas apresentações foram usados diferentes recursos que procuraram tornar mais compreensíveis os conceitos científicos envolvidos e as técnicas de detecção de exoplanetas. Em particular, considerou-se o caráter interdisciplinar da ciência dos exoplanetas, bem como, conhecimentos relacionados à história da astronomia.Palavras-chave: Astronomia; Ensino de Física; Divulgação da Ciência; Detecção de Exoplanetas. Scientific dissemination activities on exoplanetsAbstract: This work investigated the results and impacts of scientific dissemination activities on the science of exoplanets, which took place in 2018, with students from four schools of basic education located in municipalities on the north coast of São Paulo. These actions allowed students to gain a better understanding of the concepts presented about exoplanets and sought to encourage further study in areas of astronomy. For the elaboration of the presentations, it was studied both the current state of the existing scientific knowledge about exoplanets, as well as the way the didactic work with astronomy themes can be carried out with elementary and high school students. In the presentations, different resources were used to make the scientific concepts involved and the techniques for detecting exoplanets more understandable. In particular, the presentations considered the interdisciplinary nature of the science of exoplanets, as well as knowledge related to the history of astronomy.Keywords: Astronomy; Physics Teaching; Dissemination of Science; Exoplanet Detection.
Resenha do livro a formação matemática do professor: licenciatura e prática docente escolar
Authors: Pachêco Franklin Fernando Ferreira , Ferreira Alan Gustavo
Published: December 2021

Resumo: Esse texto apresenta uma resenha referente do livro intitulado “A formação matemática do professor: licenciatura e prática docente escolar” produzido pelos autores Plínio Cavalcanti Moreira e Maria Manuela M. S. David, integra a coleção Tendências em Educação Matemática.
O ensino de ciências para alunos com deficiência visual: identificando limites e possibilidades por meio de uma revisão sistemática da literatura
Authors: Mariano Halanda de Matos , Fernandes Geraldo Wellington Rocha , Soares Raquel Schwenck de Mello Vianna
Published: December 2021

Resumo: Este trabalho tem o objetivo de caracterizar as pesquisas em ensino de Ciências referentes aos alunos com deficiência visual. Trata-se de uma pesquisa com abordagem qualitativa, através de uma revisão sistemática de trabalhos publicados em eventos nacionais e periódicos da área de ensino de Ciências com Qualis Capes A1/A2. O instrumento de análise dos dados foi a Análise Textual Discursiva (ATD). Os resultados foram divididos em duas partes. A primeira buscou caracterizar o levantamento bibliográfico dos trabalhos publicados em ensino de Ciências sobre alunos com deficiências visuais. A segunda parte caracteriza os limites e possibilidades sobre esta temática, através de quatro categorias emergentes: 1) Inclusão e o ensino de Ciências; 2) Formação de professores de Ciências e deficiência visual; 3) Construção, uso ou análise de materiais didáticos adaptados para alunos com deficiência visual no ensino de Ciências; e 4) Reflexões epistêmicas no ensino de Ciências para alunos com deficiência visual.Palavras-chave: Deficiência Visual; Baixa Visão; Ensino de Ciências; Educação Inclusiva. Science education for students with visual impairment: identifying limits and possibilities through a systematic literature reviewAbstract: This work aims to characterize research in science education related to students with visual impairment. This is a research with a qualitative approach, through a systematic review of works published in national events and journals in the field of science teaching with Qualis Capes A1/A2. The data analysis instrument was the Textual Discursive Analysis (TDA). The results were divided into two parts. The first sought to characterize the bibliographic survey of works published in science teaching about students with visual impairments. The second part characterizes the limits and possibilities on this theme, through four emerging categories: 1) Inclusion and the science teaching; 2) Training of science teachers and visual impairment; 3) Construction, use or analysis of didactic materials adapted for students with visual impairments in science teaching; and 4) Epistemic reflections on science teaching for visually impaired students.Keywords: Visual impairment; Low vision; Science education; Inclusive education.
Contribuições das pesquisas em ensino de ciências e matemática atinentes à produção escrita
Authors: Ribas Jeferson Ferreti , Broietti Fabiele Cristiane Dias
Published: December 2021

Resumo: Neste artigo apresentamos resultados de uma pesquisa de caráter bibliográfico, com a intenção de conhecer as investigações atinentes à produção escrita (PE) presentes em trabalhos acadêmicos da área de Ensino de Ciências e Matemática. Com o intuito de identificar em que contexto de investigação a produção escrita foi empregada e como os autores desses trabalhos compreendem o termo produção escrita, utilizamos os procedimentos metodológicos da Análise de Conteúdo para selecionar e analisar 65 Dissertações e 17 Teses. Como resultados, evidenciamos que as pesquisas em Ensino de Ciências e Matemática utilizaram a produção escrita como instrumento de aprendizagem ou como instrumento formativo, uma vez que objetivaram investigar os conhecimentos mobilizados pelos sujeitos que realizaram a PE ou estiveram relacionadas à aprendizagem docente dos sujeitos que analisaram ou realizaram a PE. Constatamos, também, que a produção escrita apresentada nesses trabalhos acadêmicos consistiu em registros escritos, desenhos, representações geométricas, colagens e resoluções matemáticas.Palavras-chave: Produção escrita; Pesquisas acadêmicas; Ensino de Ciências e Matemática. Contributions of research in science and mathematics teaching related to writtten productionAbstract: In this article, we present results of a bibliographic research with the intention of knowing the investigations related to the written production in academic research in the area of Science and Mathematics Teaching. In order to identify in which research context was employed the written production and how the authors of these works understood written production, we used the methodological procedures of Content Analysis to select and analyze 65 Dissertations and 17 Theses. As a result, we found that research in Science and Mathematics Teaching used written production as a learning tool or as a training tool, since they investigated the knowledge mobilized by the subjects who carried out the written production, or were related to the teaching learning of the subjects who analyzed or carried out the written production. We also verified that the written production presented in these academic works consisted of written records, drawings, geometric representations, collages and mathematical resolutions.Keywords: Written production; Academic research; Science and Mathematics Teaching.
Acesso aberto: desafios
Authors: Ferrari Lima Dartel , Meglhioratti Fernanda Aparecida , Franzen Leite Rosana
Published: December 2021

Resumo: A discussão a respeito da importância de acesso aos produtos e processos de pesquisa para promover o conhecimento científico tem sido objeto de reflexão há muito tempo na literatura. Na atualidade, as reflexões a respeito do livre acesso à produção científica se intensificam pressionadas pelo acesso à internet e a velocidade em que as informações são disponibilizadas. Nesse contexto, discutimos as ações que a ReBECEM tem realizado para manutenção de um modelo aberto e sem custos para autores e leitores.Palavras-chave: Acesso aberto; Política editorial; Publicação científica.
Prediction of the number of consumed disc cutters of tunnel boring machine using intelligent methods
Authors: Afradi Alireza , Ebrahimabadi Arash , Hallajian Tahereh
Published: December 2021

Purpose. Disc cutters are the main cutting tools for the Tunnel Boring Machines (TBMs). Prediction of the number of consumed disc cutters of TBMs is one of the most significant factors in the tunneling projects. Choosing the right model for predicting the number of consumed disc cutters in mechanized tunneling projects has been the most important mechanized tunneling topics in recent years. Methods. In this research, the prediction of the number of consumed disc cutters considering machine and ground conditions such as Power (KW), Revolutions per minute (RPM) (Cycle/Min), Thrust per Cutter (KN), Geological Strength Index (GSI) in the Sabzkooh water conveyance tunnel has been conducted by multiple linear regression analysis and multiple nonlinear regression, Gene Expression Programming (GEP) method and Support Vector Machine (SVM) approaches. Findings. Results showed that the number of consumed disc cutters for linear regression method is R2 = 0.95 and RMSE = 0.83, nonlinear regression method is – R2 = 0.95 and RMSE = 0.84, Gene Expression Programming (GEP) method is – R2 = 0.94 and RMSE = 0.95, Support Vector Machine (SVM) method is – R2 = 0.98 and RMSE = 0.45. Originality. During the analyses, in order to evaluate the accuracy and efficiency of predictive models, the coefficient of determination (R2) and root mean square error (RMSE) have been used. Practical implications. Results demonstrated that all four methods are effective and have high accuracy but the method of support vector machine has a special superiority over other methods.
Substantiation of resource-saving technology when mining the deposits for the production of crushed-stone products
Authors: Cherniaiev Oleksii , Pavlychenko Artem , Romanenko Oleksandr , Vovk Yurii
Published: December 2021

Purpose. Scientific substantiation of the expedient depth of mining the non-metallic deposits of rocky minerals on the basis of mathematical and statistical methods, which will ensure resource-saving and rational use of natural resources. Methods. To solve the purpose set, the following methods are used: graphical-analytical – when optimizing the maximum depth of mining the deposits of building materials, and the method of mathematical modeling – for determining the maximum depth of mining the non-metallic deposits with internal dumping. By means of statistical processing according to systematized types of deposits, the patterns of a change in the maximum depth of mining the basic deposits, depending on the main parameters of the quarry field, have been studied. Findings. A new methodology, which is distinguished by taking into account in-pit dumping, has been developed for calculating the maximum depth of granite quarries, which most of all influences the efficiency of mining operations and the value of economic indicators while ensuring the maximum economic effect with the achievement of a rational maximum depth of mining the deposit. A new, theoretically substantiated methodology has been created for determining the maximum depth of mining the mineral deposits for the production of crushed-stone products while providing the resource- and land-saving during the quarry operation. Originality. For the first time for these deposits, the dependence of their maximum mining depth on the main parameters of the quarry field and the place of internal dumping of overburden rocks has been determined. This has become a determining factor in the appropriate mining of deep non-metallic deposits of building materials with internal dumping, which provides a minimal land disturbance. Practical implications. The research results have been tested and implemented in working projects for mining the Liubymivske, Chaplynske, Pervomaiske, Mykytivske, Trykratske and Novoukrainske granite deposits; as a result of additional mining of mineral reserves, their additional increment in the volume from 1 to 48 million m3 is possible, which will ensure 5-40 years of sustainable operation of the mining enterprise.
Determination of number of Extracranial and Intracranial Atherosclerotic Arterial Stenosis in Patients of Ischemic Stroke with Diabetes Mellitus under DSA Evaluation
Authors: Hoque Chowdhury Mohammad Shah Jahirul , Baqui Murshed , Islam Chowdhury Md Towhidul , Ahmed Nayeem , Islam Md Nahidul , Mukherjee Sudipta Kumar , Rahman Mohibur , Khan Sharif Uddin , Mohammad Quazi Deen
Published: December 2021

Objective: To evaluate the solitary & multiple site of extracranial and intracranial atherosclerotic arterial stenosis in patients of ischemic stroke with diabetes mellitus.

Methodology: This retrospective observational study was conducted among the patients having ischemic stroke with diabetes mellitus who were admitted in Dhaka Medical College & Hospital (DMCH) out patient department during March 2010 to February 2011. A total of 30 patients with ischemic stroke and diabetes mellitus were included in the study. CT scan of brain was done to every patient to confirm the diagnosis. Digital subtraction angiography was performed for complete evaluation.

Result: The mean (±SD) age was 57.9±9.2 years with a range from 43 to 80 years and male female ratio was 29:1. Among 21 patients with extracranial stenosis, either single, double and triple or more lesions were found in 53.3%, 85.7% and 87.5% of patients respectively. Again among 9 patients with intracranial stenosis, it was observed that 46.7% of patients had single lesion stenosis, 14.3% of patient had double lesion stenosis and 12.5% of patients had triple or more lesion stenosis. Double (85.7%) and triple (87.5%) lesions were significantly (p<0.05) higher in extracranial stenosis compared to intracranial stenosis (14.3% and 12.5% respectively). Most (78.9%) of the patients had >70% stenosis in extracranial arteries and 21.1% in intracranial arteries. Patients with >70% stenosis were significantly (p<0.05) higher in extracranial arteries.

Conclusion: A conclusion can be made from the above mentioned result that occurrence of multiple site of lesions and more severe stenosis occurred more in extracranial group than in intracranial group of ischemic stroke patients among diabetic population of Bangladesh.

Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 1-4
Efficacy, Safety and tolerability of the once-daily 10 cm² rivastigmine patch formulation in the patients with dementia (with probable Alzheimer’s disease)
Authors: Haque Anisul , Mohammad Quazi Deen , Bhowmik Nirmalendu Bikash , Roy Biplob Kumar , Islam Md Rafiqul , Khan Md Rezaul Karim , Alam Md Badrul , Chowdhury Shamsul Haque , Alpha SAM Masihuzzaman , Das Khokon Kanti , Haque Md Amirul , Ghose Triptish Chandra , Ali Tanvir Mobarak , Hasan Farzana
Published: December 2021

Back ground: Treatment compliance in patients with Alzheimer’s disease is particularly important as patients receiving regular treatment have a greater chance of slowing or delaying disease progression. Transdermal delivery has the potential for providing continuous drug delivery and steady plasma levels. Current study aimed to evaluate safety and tolerability of rivastigmine patch, to assess patient compliance and to assess the efficacy of treatment in patients with dementia (with probable Alzheimer’s disease).

Methods: A total of 112 dementia patients (with a diagnosis of probable Alzheimer’s disease) from 12 centers were enrolled who were residing with someone in the communities throughout the study. After eligibility, and baseline assessments, patients were entered a 24-week open label treatment phase. All patients were started with application of one 5 cm² patch, followed by an up-titration to the target dose of 10 cm² patch size. Efficacy assessments were performed at weeks 12 and 24 in terms of MMSE and GDS score. Safety was monitored at all assessment points based mainly on the frequency of adverse events.

Results: Analysis of baseline and available data until the drop out revealed no significant differentials. Around 95% of the study participants could receive 10 cm² patch size, showing a very high tolerability of the patch. Concurrent medication use also showed significant reduction to 16.3% patient in the end from 25% at baseline. The average MMSE score increased to 19.3 (±3.1) at 12th week and to 20.6(±3.4) at 24th week from 16.8 (±3.2) at baseline. GDS score reduced to 3.7 (±1.4) at 12th week and to 3.2 (±1.3) at 24th week from 4.3 (±1.5) at baseline. Only eight occasions of adverse event was reported (8.2%); no serious adverse event (SAE) were reported. Lost to follow up in the study was 14 (12.5%). Analysis of baseline data shows no significant difference. Their withdrawal seems to be unrelated to the adverse events and treatment outcome. Among the lost to follow up only one 1 (7.1%) had some side effect.

Conclusion: Our study supports the pharmacokinetic rationale for the rivastigmine patch, indicating that smooth and continuous delivery of rivastigmine translates into an improved tolerability profile versus conventional oral administration, while maintaining clinical effectiveness.

Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 5-14
The Relationship between Risk Factors and Microalbumiuria for Ischemic Stroke- A Case Control Study
Authors: Wadud Md Shaheen , Rahman Aminur , Shahi Mohammad Selim , Ahmed A K Takib Uddin , Saha Uttam Kumar , Ali Zahed , Kundu Narayan Chandra , Hossain Sakhawat , Quraishi Firoz Ahmed , Islam Md Rafiqul
Published: December 2021

Background: Epidemiologic studies have reported that microalbuminuria is a risk factor for stroke in men and a limited case control study found that the highest quintile of microalbuminuria values was associated with 13 fold increased risk for stroke. The goal of this study was designed to determine its relationship to risk factors for ischemic stroke.

Materials and Methods: It was a prospective observational study conducted in the Department of Neurology, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh. Fifty consecutive patients with ischemic stroke were enrolled in this study, with at least two risk factors that fulfilled the inclusion criteria and were confirmed by CT or MRI of brain. Equal number of controls of same age group without stroke who had at least two risk factors was compared with the case group. The patients were assessed clinically with structured questionnaire including blood pressure, height and weight, and monitoring blood glucose and microalbuminuria.

Results: Microalbuminuria was found 58.0% in patients with ischemic stroke. Patients who had diabetes mellitus will have 13.86 times the risk for developing of microalbuminuria (p<0.05). Patients who had hypertension will have 4.19 times the risk of developing microalbuminuria (p<0.05) and BMI (e”23 kg/m2) will have 4.24 times the risk of developing microalbuminuria (p<0.05). Whereas TIA, IHD, dyslipidemia, smoking and positive family history were not significantly (P>0.05) associated with microalbuminuria in patients with ischemic stroke.

Conclusion: The findings of this study show that diabetes is the factor most closely associated with microalbuminuria followed by HTN and BMI >23 kg/ m2 with statistically significance in patients with ischemic stroke.

Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 43-53
Juvenile Myasthenia Gravis: A Case Report and Review of Literatures
Authors: Kundu Narayan Chandra , Sen Moushumi , Joy KM Nazmul Islam , Quraish Feroj Ahmed
Published: December 2021

Juvenile myasthenia gravis (JMG) is a rare autoimmune disorder of childhood. Pediatric presentation of MG is more common in Oriental than in Caucasian populations. JMG need to be differentiated from congenital myasthenia gravis which do not have haan autoimmune basis. An 11 years old girl presented with drooping of eye lids which was more marked at the later part of day and was gradually progressive . She had complained of double vision. She had no family history of myasthenia gravis. Ice pack test, repetitive nerve stimulation test, and anti acetylcholine receptor antibody test support the diagnosis. She was treated with pyridostigmine and was started as 30mg four times daily and increased to 60 mg/qds. Subsequently her symptoms improved gradually and she became stable.

Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 64-69
Antibaterial activity of the extracts of pineapple and pomelo against five different pathogenic bacterial isolates
Authors: Nahid Hasan ATM , Saha Trisha , Ahmed Tasnia
Published: December 2021

To combat the infections caused by antibiotic resistant bacteria, natural candidates are being studied to find out antibacterial activity against the drug-resistant microorganisms. Among the variety of natural candidates of plant origin, many fruits have been proved to have potent antibacterial activity. In the current study, we chose pineapple (Ananas comosus), and pomelo (Citrus maxima) to determine their efficacy against some clinical isolates. Fruit samples were subjected to prepare crude, ethanol, methanol and aqueous extract to determine their antibacterial potency. Clinical isolates were used to determine the antibacterial activity of the extracts against them. The isolates were found to be multi-drug resistant. Out of twenty-eight antibiotics, Pseudomonas aeruginosa was resistant to ten antibiotics and Salmonella spp. was resistant to nine antibiotics. Rather than the crude extracts of the fruits, ethanol and methanol extracts showed antibacterial activity towards multi-drug resistant pathogenic bacteria. Aqueous extract did not show any significant antibacterial activity at all. Extracts of pomelo fruit exhibited the highest results whereas pomelo skin and pineapple peel crude extracts were the least effective compared to the other extracts. Ethanol extract of pineapple fruit (against all isolates but Staphylococcus aureus) and methanol extract of pomelo fruit (against all isolates) showed the lowest MIC (minimum inhibitory concentration) of 187.5 μg/ml. MBC (minimum bactericidal concentration) was found (within the range of 500 μg/ml to 1000 μg/ml) only with ethanol and methanol extracts of pomelo and pineapple. As the clinical isolates were found to be inhibited by the extracts, they can be used as an alternative for treating infections caused by these bacteria.
Stamford Journal of Microbiology, Vol.11 (1) 2021: 1-6
Physicochemical and bacteriological screening of pathogenic microorganisms from aquarium water collected from katabon area in Dhaka city
Authors: Mawa Jannatul , Munshi Saurab Kishore , Mou Amatun Nur , Nur Ifra Tun
Published: December 2021

Globally, the ornamental fish business has a high demand for its popularity as well as for its profitability. However, microbial contamination, nutrient depletion and accumulation of organic materials are the major factors in an aquafarming system which can cause death of aquatic animal and causes financial losses. This study aimed to determine the physicochemical and microbiological quality of fish aquarium water. Water of different time interval after treatment (7 days, 20 days, 30 days, 60 days, 90 days) were taken from the different aquariums. A set of physicochemical parameters such as temperature, transparency, pH, conductivity, dissolved oxygen, total dissolved solids, alkalinity, total hardness, conductivity were found within the approved standard concentration for fish. The present study also reveals the microbiological status of the aquaculture water where the total viable count ranging from 2.20×104 to 4.20×104 cfu/ml. Escherichia coli, Staphylococcus spp., and Pseudomonas spp. were present in all samples. Antimicrobial susceptibility tests were also done to determine the antibiotic resistance pattern of microbes isolated from aquarium water.
Stamford Journal of Microbiology, Vol.11 (1) 2021: 20-23
Characteristics of Chest X-Ray in Patients with Cancer at the Dharmais Cancer Hospital Emergency Room during the COVID-19 Pandemic
Authors: Sakti Bima Taruna , Rosalina Rosalina , Pradipta Jaka
Published: December 2021

Background: Conventional chest X-ray (chest X-ray) in Dharmais Cancer Hospital emergency room (ER) is still the primary modality to diagnose patients with cancer with dyspnoea complaints. Chest X-ray was also carried out to screen inpatients at the Dharmais Cancer Hospital ER at the beginning of the COVID-19 pandemic in Indonesia. It was essential because patients in the Dharmais Cancer Hospital ER were patients with cancer, with low immunity and a high risk of being exposed to various infections. Thus, the purpose of this study was to determine the characteristics of chest X-rays in patients with cancer at the Dharmais Cancer Hospital ER during the COVID-19 pandemic in February-May 2020. Methods: This was a descriptive study. The population involved was all patients at the Dharmais Cancer Hospital ER who received chest X-ray support, with the inclusion criteria for diagnosing lung cancer, breast cancer, cervical cancer, colorectal cancer, and blood cancer (Leukemia) from February to May 2020. Data analysis employed univariate analysis by utilizing tables and graphs in presenting the data.Results: 289 samples met the research criteria. The highest visits were patients with breast cancer (41.2%). The most common thoracic images were pleural effusion (34.3%), followed by bronchopneumonia (31.1%), normal lung (16.6%), lung mass (7.6%), pneumonia (5.2%), and others (5.2%), consisting of atelectasis, bronchitis, fibrosis/chronic pulmonary process, pulmonary emphysema, cardiomegaly, and specific process. Besides, the chest x-ray bronchopneumonia was 31.1% (90 samples), accompanied by pleural effusion of 44.4%. From the chest X-ray, pleural effusions were 34.3% (99 samples), with lung cancer being the most common with pleural effusions (48.4%).Conclusions: More than 80% of chest x-ray performed in the ER are abnormal. Also, breast cancer is the highest in the Dharmais Cancer Hospital ER cases, with the highest chest x-ray of pleural effusion.
Construction of Networks by Associating with Submanifolds of Almost Hermitian Manifolds
Authors: GÜRSOY Arif
Published: December 2021

The idea that data lies in a non-linear space has brought up the concept of manifold learning as a part of machine learning and such notion is one of the most important research fields of today. The main idea here is to design the data as a submanifold model embedded in a high-dimensional manifold. On the other hand, graph theory is one of the most important research areas of applied mathematics and computer science. As a result, many researchers investigate new methods for machine learning on graphs. From the above information, it is seen that the theory of submanifolds and graph theory have become two important concepts in machine learning and nowadays, the geometric deep learning research area using these two concepts has emerged. By combining these two fields, this article aims to present the relationships between submanifolds of complex manifolds with the help of graphs. In this paper, we build some directed networks by identifying with submanifolds of almost Hermitian manifolds. Moreover, we give some results and relations among holomorphic submanifolds, totally real submanifolds, CR-submanifolds, slant submanifolds, semi-slant submanifolds, hemi-slant submanifolds, and bi-slant submanifolds in almost Hermitian manifolds in terms of graph theory.
A Virtual Assistant Design and Application on Industrial Database
Authors: ÇINAKLI Muhammed , ARTA Merve , DEMİRDAĞ Melike , SEÇKİN Ahmet Çağdaş
Published: December 2021

The development and advancement of technology allows people to access information in a variety of ways. Whether in commerce, marketing or communication, the amount and variety of data is increasing in every field. Collecting this data in different fields and drawing conclusions based on the data has become very important for the development of individuals, companies, industries, and countries, and especially collecting this data in databases has become popular. In this paper, an industrial database was created, a wireless sensor network was set up using ZigBee protocol for data collection, the collection of data in the database was done quickly and cheaply, and a natural language processing based Virtual Assistant was created to query the data. Unlike other traditional rule-based methods, Virtual Assistant has a non-predetermined structure that allows Virtual Assistant to answer different types of questions from the user. The communication between the created Sensor Network, database and Virtual Assistant is done using XMPP message protocol. Again, with the help of this protocol, a system is presented to communicate with the user. With the method presented in the study, the data in the relational database was made queryable regardless of location and platform. With the virtual help system provided, the distance between natural language and computer language is shortened and people can get information quickly and easily.