bluuebunny/crossref_metadata_2025 huggingface dataset:
Ecological and Faunistic Features of Helminths in Cattle in Uzbekistan
Authors: S. Dadayev
Published: November 2022

This article involves the fauna and ecological features of helminths of cattle in various biocenoses of Uzbekistan. Based on many years of our own research and analysis of literature data, 71 species of helminths were identified in cattle of Uzbekistan, of which 12 species belong to the class of cestodes, 12 species to trematodes and 47 species to nematodes. Of the 71 species of helminths identified in cattle of the Republic, 1 species (Stephanofilaria assamensis) was noted by us for the first time in the CIS and 11 species (Moniezia alba, Trichocephalus globulosa, Bunostomum trigonocephalum, Camelostrongylus mentulatus, Cooperia punctate, C. pectinata, Grosspiculagia occidentalis, Nematodirus abnormalis, N. spathiger, Stephanofilaria assamensis, Thelazia skrjabini) in Uzbekistan. Among the identified parasitic worms of cattle in Uzbekistan, 37 species develop in a direct way, i.e. they develop without the participation of intermediate hosts. The remaining 34 species of helminths develop with the participation of intermediate and additional hosts. Their intermediate and additional hosts are freshwater and land mollusks, oribatid mites, grasshoppers, ants, dipterous insects, predatory mammals, and humans. Also, it was determined that of the 71 species of helminths Paramphistomum ichikawai, Taeniarhynchus saginatus, Trichocephalus globulosa, Aonchotheca bovis, Thelazia rhodesi, Th. gulosa, Th. skrjabini, Th. Petrovi, Onchocerca lienalis, Stephanofilaria stilesi and S. assamensis parasitize only cattle. Under the conditions of Uzbekistan, the total infection of cattle with helminths is 94.3%. At the same time, in some regions of Uzbekistan, infection of cattle with trematodes ranges from -34.0 to 66.6%, cestodes from 17.6 to 45.1% and nematodes from 70.0 % to 93.5 %. Among the widespread helminthiases of cattle that adversely affect their productivity are monieziosis, fascioliasis, paramphistomidiasis, trichuriasis, hemonchosis, parabronemiasis, thelaziosis, stephanofilariasis and other helminthiases.
Practical Mechanisms for Training of Education Managers for Innovation and Evaluation of their Effectiveness
Authors: Yashin U. Ismadiyarov
Published: November 2022

The article is devoted to the preparation and assessment of the effectiveness of training of education managers for innovations in the system of higher pedagogical education by conducting an empirical study; structural and logical evaluation scheme is described; analysis of the dynamics of managers' readiness for innovative management in comparison groups is carried out.
Teaching Foreign Languages based on Games in Non-philology Higher Education Institutions (In English as an Example)
Authors: Tursunoy Sh. Karshiyeva
Published: November 2022

This article is written about the main principles and methods of education that serve to achieve the intended goals using didactic games in teaching foreign languages in non-philological higher educational institutions. The essence of all the reforms implemented in the field of education is focused on one thing, that is, the use of didactic games in teaching foreign languages, improving the quality of education, spending less effort and achieving more efficiency in the process of practical training. The game method - during the practical training of a foreign language, by increasing the activity between the teacher and the students, it guarantees their mutual knowledge acquisition.
Mitigate the reverse effects of frost by cultivate tomato plants under different types of mesh cover for low tunnels
Authors: Ahmed S. Mohamed  , Said A. Saleh  , A. A. Glala  , Samar S. Halawa
Published: November 2022

Tomato plants are highly sensitive to chilling stress so this experiment was conducted during successive winter seasons of 2020/2021 and 2021/2022 to investigate the possibility of sustaining production and quality of tomato yield under cold conditions by using different types of mesh cover for low tunnels. Two commercial cultivars, i.e., Super gold F1 and Super streen F1 were used. Seedlings were transplanted under different types of mesh cover for low tunnels. Three types of mesh cover (63%, 65%, 73%) had done to cover the plants of all tested seasons compared to open field condition (control "Without cover"). Results show that significant differences were observed among the two hybrid varieties of tomato studied, in terms of their vegetative growth characteristics (plant height, number of branches, number of leaves, fresh weight, dry weight and leaves area) as well as yield and fruit quality characteristics (Fruit set, total yield, firmness, T.S.S and Vit. C. ‘Super gold’ exhibited significantly higher values for these characteristics, compared to ‘Super strain B’. Chilling reduced the growth parameters (plant height, number of leaves, number of branches, plant fresh weight, plant dry weight) for control plants (without cover) compared to the coverage treatments (63%, 65%, 73%). Significant highest results in the growth, chemical composition of tomato leaves as well as yield and fruit quality parameters were obtained with covering tomato plants by white mesh cover 63% flowed by 65% of treatments which were best than the chilled plants. Concerning the interaction between hybrid varieties and covering treatments, it can be noticed that Cv. Super gold F1 which grown under white mesh cover 63% recorded a highly significant increases in plant height, number of branches, number of leaves, fresh weight, dry weight, leaves area, N, P, K, total chlorophyll, total proline, total sugers contents, fruit set, total yield, firmness, T.S.S and Vit. C. when compared to Cv. Super streen B F1 which grown in open field (without coverage).
The efficiency of SCoT, ISSR, and SRAP markers for detecting genetic polymorphism among Egyptian barley genotypes
Authors: Nourhane O.Abaza  , Sawsan S. Yousief  , Reda E.A. Moghaieb
Published: November 2022

The results of the present study support the idea that, the tested Egyptian barley cultivars could make a useful case study for genetic diversity research. When those cultivars were examined using three distinct markers (codon targeted (SCoT), sequence-related amplified polymorphism (SRAP) and inter-simple sequence repeats (ISSR)). According to SRAP, ISSR, and SCoT analyses, respectively 85, 76, and 66 polymorphism percentages among the seven tested barley cultivars were detected. The genotype specific markers for each genotype used were determined. The data revealed that Giza127 had the highest number of unique markers, showing six specific SCoT markers, three specific SRAP markers, and one specific ISSR marker. The genetic relationships between the seven Egyptian barley cultivars are explained by the phylogenetic tree built using information gathered from various molecular markers. These gene-based molecular markers demonstrated the reliability of SCoT, ISSR, and SRAP molecular markers for identifying DNA polymorphism levels and genetic relationships in barley.
Encapsulation of Brunfelsia pauciflora microprogated shoots as a suitable conservation protocol
Authors: Tarek A.A  , Shimaa A. Shaaban  , Lobna S. Taha  , Kh. I. Hashish  , Ahmed M.M. Gabr  , Awatef I.A.R.Ali
Published: November 2022

The percent work aimed to establish an efficient in vitro propagation and conservation protocol for Brunfelsia pauciflora plant using encapsulation techniques that allow the genetic stability of conserved material. The effect of plant growth regulators types (BAP, Kin, 2ip, and NAA) and concentrations at 0.0, 1.0, and 2.0 mg/l were stud-ied during the establishment phase in comparison with a hormonal-free medium. In vitro proliferated shootlets were encapsulated using various levels of sodium alginate at 1, 2, and 3% (W/V) and calcium chloride at 2.5,5 and 10 %. The regrowth ability of encapsulated explants was evaluated after conservation for 3, 5, and 7 weeks and compared with non-encapsulated buds. The findings of the current study proved that during the establish-ment phase, applying BAP at 2.0 mg/l gave the best results during the three successive subcultures. The best treatment 2ip (2.0mg/l) + BAP (2.0mg/l) + NAA (2.0mg/l) that was considered ideal propagation protocol for shooting and rooting of Brunfelsia. Successful plant recovery from encapsulated explants using low concentra-tions of sodium alginate (1%) and calcium chloride at 2.5% proved that the explants could to survive at the high-est percent (100%) during conservation periods 3, 5, and 7weeks. Increasing calcium chloride to 5% with the same concentration of sodium alginate (1%) caused a gradually reduced percent of survival to 53.33% with an increasing conservations period (from 3 to 7weeks). It is the first paper on the application of the syndetic seed technique on Brunfelsia for the shortest period of conservation and successive renovation of shootlets whose genetic stabilization was evaluated by analysis of RAPD that proved that the genetic similarity ranged from 56.1 to 80%. These results were confirmed by anatomical sections made in Brunfelsia leaf blade.
An economic repercussion to the impact of climate change on the most important Egyptian food security crops
Authors: Mamdouh El Badry Taha  , Moataz Eliw  , Ahmad Eid Elesawi  , Hala Mohamed Ali Shehata  , Dina Mamdouh Ewis  , Asma Talat Goma
Published: November 2022

We examine how the Climate Change affected on the Agricultural Production , and how the impact of climatic changes on the productivity of the most important grain crops in Egypt, with the aim of determining the extent to which productivity has changed due to climate change in Egypt, using the Autoregressive Distributed lagged methodology (ARDL), where it was found that there is an inverse relationship between climate changes and the productivity of the most important cereal crops, a relationship that is consistent with the economic logic. The results indicate that a similar negative impact of the maximum temperature change on the productivity of the most important cereal crops in the long term, which is consistent with an economic theory.
Determination of the effective of chemical mutagenesis using sodium azide to improvement of vegetative growth and flowering characteristics in Helichrysum bracteatum L. plant
Authors: El-Khateeb, M.A.  , Rawia, A. Eid  , Hashish, Kh.I  , Ashour, H.A.  , Radwan, R.M.S.
Published: November 2022

This study were carried out on Helichrysum bracteatum L. plant at the Experimental nursery of the Ornamental Hort. Dept., Fac. Agric., Cairo Univ., Giza, Egypt, during the two successive seasons (2014/15 and 2015/16). The aim of this study was to investigate the effect of on some vegetative and flowering parameters and anatomical structure of leaves and flowers. Seeds of H. bracteatum L. were exposed to four concentrations of (0.05, 0.1, 0.2 and 0.3%) of sodium azide (NaN3) solution for six hours; one set of seeds was kept without sodium azide treatment (untreated) to act as control. The obtained data revealed that the low concentration of sodium azide (SA) increased plant height, number of leaves/ plant, stem diameter (cm) number of flowers, flowers fresh weight (g)/plant and flowers dry weight (g)/plant in M1 and M2. The ratio of chlorophyll (a and b) showed a markedly decrease as a result of increasing sodium azide concentrations. On contrary, in case of carotenoids showed a markedly increase as a result of decreasing sodium azide concentrations. Were obtained on many morphological mutants in flowers through two generations. Some parameters of anatomical structure of leaves and flowers and to confirm the stability of some of the mutations were obtained during the second generations.
AUTOMATED SYSTEMS AS A FACTOR AFFECTING ON FLOWERS PLANT HARVESTING
Authors: Dina S. Salama  , Mohamed Y. Tayel  , M. M. Ibrahim  , Gamal E. M. Nasr
Published: November 2022

In the last decade, the adoption of fully automated systems in agricultural operations has become an urgent need due to high labor costs and low efficiency. The harvesting process is one of those agricultural activities that require a lot of work in addition to high costs. The study investigates different fully automated harvesting systems for one of the most important crops, medicinal and aromatic plants, especially flowers which are involved in many industries and characterized by high economic importance in the global trade balance of crops. Process technologies that include harvest automation and standardization of the automated system detection problems and accuracy were analyzed and compared. Finally, to solve the various problems that facing the cutting flowers production, it is necessary to accelerate the development of mechanized harvesting, realize the mechanization of information acquisition and standardization in order to advance precision agriculture and agricultural wisdom for the future.
The Therapeutic Applications Of Aptamers And Aptamer-Conjugated Nanoparticles In Cancer, Inflammatory And Viral Diseases
Authors: Dharmesh Ravat  , Aradhana Patel  , Pragnesh Patani
Published: November 2022

Health care modalities that are more predictable and effective are the result of advances in early diagnosis and precise treatment options. Aptamers are three-dimensional structures made of nucleic acids that selectively bind to a target site. In the creation of aptamer-based drug delivery systems, the physicochemical properties of aptamers, their conjugation with nanoparticles (NPs) in theranostics, and their internalization have been found to be of interest.As a result, our goal was to provide an overview of the structure and production of aptamers, followed by the benefits of aptamer-conjugated nanoparticles and their applications as theranostics in oncology, inflammatory, and viral diseases. After that, a number of reports on aptamer internalization strategies, the efficiency of aptamers in comparison to their analogs, and the implications of aptamers for clinical trials were discussed. Last but not least, we talked about the problems that actively targeted aptamers face right now and what the future holds for their use in medicine. In conclusion, aptamer-based therapeutic platform development in clinical trials may benefit greatly from this review.
GOLD NANOPARTICLE USED IN CANCER THERAPY
Authors: Jaivik Patel  , Yashica Rawal  , Pragnesh Patani
Published: November 2022

Recent fast developments in nanotechnology have stoked a developing interest in the study of nanoparticles, particularly when it comes to medical applications. Understanding the properties of gold nanoparticles (AuNPs) and doing extensive study has resulted to a growing body of information that is pushing the limits of nanotechnology in interesting directions all the time. The use of AuNPs to manage cancer, including its diagnosis, monitoring, and therapy, appears to be of increased attention at the moment. The goal of these initiatives is to fundamentally alter the way that cancer is currently treated. In this article, we will primarily focus on how AuNPs are currently being used to treat cancer.
THE CLINICAL PHENOTYPE OF IDIOPATHIC, SPONTANEOUS FACIAL PAIN DISEASE
Authors: Margi Patel  , Aradhana Patel  , Pragnesh Patani
Published: November 2022

The fifth and greatest cranial nerve, the trigeminal nerve (V), is in charge of detecting sensory inputs that come from the craniofacial region. The trigeminal ganglia house the cell bodies of the three branches of the nerve: the ophthalmic (V1), maxillary (V2), and mandibular (V3). These branches connect to second-order neurons in the trigeminal brainstem sensory nuclear complex. Trigeminal neuralgia is one of the most prevalent types of facial and cranial discomfort. Trigeminal neuralgia is characterized by abrupt, fleeting, and painful facial pain episodes in one or more of the V branches. As a result, the quality of life for those who suffer from the condition is drastically reduced.
Chitosan Nanoparticle And Its Application In Non- Parenteral Drug Delivery
Authors: Meet Patel  , Yashica Rawal  , Pragnesh Patani
Published: November 2022

This study's main goals are to give an overview of chitosan-based nanoparticles used in a variety of non-parenteral applications and to call attention to new research on mucoadhesive and sustained release chitosan dosage forms. Chitosan is a biodegradable, biocompatible polymer that has been certified for use in wound dressings and is suitable for inclusion in human diets. For a variety of drug delivery methods, chitosan has been employed as a drug carrier in polymeric nanoparticles. Chitosan is a polymer with numerous possible uses since it has chemical functional groups that can be altered to serve particular purposes. The positive surface charges and mucoadhesive qualities of nanoparticles (np) made of chitosan and chitosan derivatives enable them to stick to mucous membranes and gradually release the therapeutic payload. This review will include examples of non-parenteral drug delivery techniques for treating eye infections, cancer, gastrointestinal disorders, pulmonary disorders, and cancer. Both in vitro and a few in vivo investigations show that chitosan has a low level of toxicity. This review looks at recent investigations on the characteristics, modifications, toxicity, pharmacokinetics, and preclinical trials of nanoparticles (np) made of chitosan for non-parenteral drug delivery.
Nanobots: Future and Development
Authors: Rinkal Padshala  , Vijendra Rajan  , Pragnesh Patani
Published: November 2022

This review paper gives overview of the present status and further development in nanorobotics. Nanobots are very tiny machines designed to perform a specific task whose components are at or close to the scale of a nanometer. As consequence of nanotechnology, new technique consisting of device coming into market among these nanobots fields opportunity in cure of human illness. This bots are made of a single strand of DNA folded into desired shape. Bots will have two states – an “off” position, where the clamshells are closed tightly to bypass healthy cell without any damage and an “on” position, where clamshell opens up to expose cancerous cell from human body. In this paper included about method of working, composition, types, challenges in development and properties of nanobots.
Colon targeted drug delivery systems: Based on Polymers
Authors: Saumil Patel  , Adarsh Bhadoria  , Pragnesh Patani
Published: November 2022

Research on colon-targeted polymers delivery systems is ongoing for conditions such ulcerative colitis, Crohn's disease, colon cancer, as well as the delivery of peptide or protein medications and vaccines. For colon-specific disorders in particular, focused nano-drug delivery to the colon is helpful because nanoparticles can build up in sick areas, improve therapeutic efficacies, and allow localized therapies, which lower systemic toxicity. The efficient delivery of NDDS to the colon, however, may be hampered by a number of obstacles, including burst drug release, enzyme and acidic degradation of drug and carrier in the stomach, pH fluctuations, mucus trapping, and systemic uptake in the upper small intestine. These obstacles might be surmounted with improvements in NDDS, resulting in effective drug delivery for colon-specific illnesses. This review provides an updated summary of recent advances in the development of orally administered NDDS for colon targeting and the future advancements in this research. It also discusses some potential colon-specific drug delivery areas, challenges faced by colon-targeted oral delivery systems, and potential drug delivery areas.
A REVIEW ON HERBAL NANOPARTICLES
Authors: Shubham Darji  , Kuntupalli Sandhya Rani  , Pragnesh Patani
Published: November 2022

They have fewer side effects than modern medications, herbal medicines have been utilised extensively throughout history and are now recognised by both doctors and patients for having a superior therapeutic value. To improve patient compliance and avoid repeated administration, phyto therapeutic require a systematic method for administering the components over time. The Crude drug can be used to accomplish this. The therapeutic benefit of Crude drug is increased by reducing toxicity and boosting bioavailability, which reduces the need for repeated administration to combat non-compliance. Nanotechnology is one of these cutting-edge strategies. Herbal medication delivery methods that are smaller than a human hair could improve plant activity and solve some of the challenges that come with it in the future.
Evaluation Of Antiurolithiatic Activity Of Methanolic Seed Extracts Of Persea Americana Against Calcium Oxalate Induced Urolithiasis In Rats
Authors: Smitha Grace S. R  , Manasa B.Y  , Jyoti Bala Chauhan
Published: November 2022

Objective: Persea Americana methanolic seed extracts are considered for the present study to access its efficacy, urolithiasis is inducedby administering the male rats with calcium oxalate.Methods: Calcium oxalate urolithiasis is induced in male rats by means of hyperoxaluria model by administering ethylene glycol of0.75% v/v, with 1% w/v ammonium chloride supplemented in drinking water for 3 days followed by 0.75% v/v of ethylene glycol for25 days. The PAMSE is administered to urolithiasis induced test group at dose of 150mg/kg respectively for 28 days.Results: As anticipated after 28 days the calcium oxalate is deposited significantly in the kidney which is associated with the increaseof Urinary oxalate, Urine calcium & magnesium levels, serum uric acid, creatinine in urolithiasis control groups. ACP, ALP, AST &ALT well known biochemical parameters are seen to be increased with decreased level of LDH assessed using kidney homogenate,copiously confirming the induction of urolithiasis , its promising to know that the PAMSE intubation to the test group daily decreasedthe quantity of formation of calcium oxalate and all the biochemical changes induced by urolithiasis is reverted.Conclusion: Results from this study shows that PAMSE is effective inhibitor of crystallization of calcium oxalate comparable to thestandard Cystone in dose dependent mode. Therefore indicating PAMSE’s significant antiurolithiatic activity.
Application of Agency Theory in the Dairy Industry of Bangladesh A Case Study of PRAN Dairy Limited
Authors: Mohamed K. Haq  , Dr. Valliappan Raju
Published: November 2022

Farmers in rural Bangladesh have been involved in the dairy industry since the 17th century. It is widely regarded as a means ofsubsistence. Milk is used in nutrition, cottage industries, and industrial dairy processing. PRAN Dairy Limited (PDL) in Bangladeshworks with rural dairy farmers under a contractual partnership to secure daily milk supplies. This study discusses PDL's relationshipwith rural dairy farmers through the lens of Agency Theory. In four districts of Northern Bangladesh, 45 farmers were selected andinterviewed; PDL has worked with them for at least ten years. This study employs the qualitative method with NVIVO12 to analyzethe interview transcripts thematically. A new version of the agency contract in the dairy industry was created by categorizing the existingone using a set of 15 codes based on five themes (risk, motivation, skills, penalties, and efforts). The study concluded that theimplications of Agency Theory in the dairy industry from Bangladesh's perspective paved the way for multidisciplinary approaches touncover more research opportunities in this sector, such as farmers' intentions to join the agency relationship with PDL.
The Impact Of Primary Hyperhidrosis On Quality Of Life Among Residents In Al-Ahsa City, Saudi Arabia
Authors: Atheer Al Sultan  , Feroze Kaliyadan  , Mahdi Aldhafiri
Published: November 2022

Background: Primary hyperhidrosis is a disease characterized as perspiration more than the body’s physiologic need and can significantly impact one’s occupational, physical, emotional, and social life. However, the prevalence and quality of life of those patients presenting for treatment have not been well studied. Objectives: To determine the prevalence of primary hyperhidrosis and its impact on the quality of life among residents in the Al-Ahsa City of Saudi Arabia. Methods: This is a cross-sectional study conducted in Al-Ahsa City by using structured questionnaires which includes two parts, first part about the subjective diagnosis of hyperhidrosis using “Hyperhidrosis Disease Severity Scale (HDSS)” and the other to assess impairment on quality of life using Amir–de Campos Clinical Protocol for Quality of Life. Results: The study revealed that 18.3% of patients were suffering from barely tolerable or intolerable excessive sweating that is interfering with daily activities indicating a severe degree of HH. A highly statistically significant correlation was found between Amir–de Campos Clinical Protocol for QoL and HDSS among patients in functional and social domain (r = 0.261; p < 0.001), under special circumstances domain (r = 0.336; p <0.001) and overall QoL (r = 0.305; p < 0.001). Conclusions: This study revealed a high prevalence of hyperhidrosis and a significant impact on the quality of life among those affected.
Solid Phase Extraction-Spectrophotometric Determination Of Isoxsuprine Hydrochloride In Different Samples Using Modified Magnetic Nanoparticales
Authors: Zaid Alnedawi  , Ali M Hassan  , Hind Hadi  , Ahmed Shabana
Published: November 2022

A green, simple and sensitive spectrophotometric method was proposed for the determination of isoxsuprine hydrochloride (ISX), based on the preconcentration with cetyltrimethylammonium bromide (CTAB) modified magnetic iron oxide nanoparticales (MNPs). ISX was coupled with diazotized metoclopramide drug via diazotization-coupling reaction in alkaline medium to form yellow-orange color product which was extracted and measured spectrophotometrically at λmax444 nm. Various parameters affecting the azo-dye removal by adsorption on modified magnetic nanoparticales (Fe3O4@CTAB) such as pH of solution, volume of diazotized reagent, volume of surfactant, amount of adsorbent and type of desorbing solvent were studied. The linear calibration graph were obtained in the concentration range of 0.3-7.0 µg/mL of ISX, the limit of detection and the limit of quantification calculated to be 0.29and 0.99µg/mL, respectively. Accuracy and precision described by relative standard deviation and relative recovery percentages. The results obtained show that the CTAB-coated MNPs could be employed in the extraction of the drug in the azo dye form from different samples. The ISX was extracted successfully in pharmaceutical forms and spiked samples of river water.
The Effect Of Smoking On Liver Enzymes And Its Functions
Authors: Rand Thair Abdulkader  , Suhair Ali Kadhim
Published: November 2022

Smoking has devastating and often fatal effects on human health. It has a wide range of harmful effects on the body, even on organs like the liver that don't come into direct touch with the smoke. On the liver, it causes three primary harms: toxic effects (both direct and indirect), immunological effects, and oncogenic consequences. The cytotoxic potential of the chemicals produced by smoking might contribute to liver cell damage. The purpose of this research was to provide a broad review of how smoking affects the enzymes and functions of the liver.
An Overview of Natural and Synthetic Coumarin Derivatives as Potential Antidiabetic Agents
Authors: Ansari Asif Husain  , Ansari Sajjad Husain  , Nandkishor Dinkarrao Gawhale  , Sharuk L. Khan  , Dhamak Vikrant Murlidhar  , Falak A. Siddiqui  , A. A. Kazi
Published: November 2022

The common term for cis-o-hydroxy cinnamic acid lactones, which all possess the fundamental structure of the benzo a-pyranone mother nucleus, iscoumarins. Especially in Umbelliferae, Rutaceae, Daphne, and Oleaceae, coumarins are extensively dispersed in the roots, stems, leaves, flowers, fruits,and seeds of higher plants. A few coumarins are also detected in certain microbes and mammals. Certain coumarin molecules may also be synthesizedartificially. We have discussed the probable mechanisms behind coumarins' anti-diabetic benefits. Numerous in vivo and in vitro studies show thatcoumarins may treat diabetes by reducing inflammation and oxidative stress, enhancing pancreatic function, and reversing aberrant insulin signaling.As a result, they are useful and need further study and development. In conclusion, it is clear that coumarins have a range of biochemical andpharmacological characteristics, some of which have potential therapeutic value that may be useful against diabetes and its consequences. To sum up,improvements in the area have allowed for the isolation or chemical design of novel advantageous compounds with coumarin cores as candidates againstdiabetes and its consequences; nevertheless, additional study is necessary before safe and effective coumarin medications are employed in the clinic.
Case Report On Giant Cell Tumour In Distal End Of Radius Left Side Managed With Chemical Cauterization And Bone Grafting
Authors: Kuldeep Chhatbar  , Sanjay Deshpande  , Salahuddin Ahmed  , Parth Shah  , Shrut Vasavada  , Devank Lohiya
Published: November 2022

Giant cell tumour of the bone is a regionally assertive neoplasm that is implemented in practice with elongated curettage andtherapeutic interventions, which would be having lesser risk of recurrence. The skeletal tumour is a single, non malignant, butregionally assertive cancer. In the fully grown skeleton, it most frequently affects the epiphysis region of bones. This is mostcommon in the femur, tibia and lower end of radius. Lower end of radius tumour makes up of about 10 percent of overall bonytumours. The obliteration of osseous and cartilages in the proximal distal radius giant cell tumour cells makes salvaging the forearmjoint morphology and feature difficult. Numerous techniques are given, such as wide excision and allograft rebuilding or ulnacentralized control with wrist fusion. We reveal, outcomes of a lower end of radius tumour adequately treated with chemicalcauterization and bone grafting, to retain forearm and hand degree of freedom and supination with better functional recovery.
Assessment Of Vaginal Infections In Pregnant Women
Authors: R P Patange  , N. S. Kshirsagar  , Shital patil  , Shilpa vhawal
Published: November 2022

Background: Vaginitis is inflammation of the vagina. Vulvovaginitis, is an inflammation of the vagina and vulva. Infection can resultin discharge, itching and pain. The present study was conducted to assess vaginal infections in pregnant women.Materials & Methods: 76 pregnant women reporting to Obstetric & Gynaecology department for vaginal infection. A detailed obstetricexamination was carried out as well. Per speculum examination was carried out and the vaginal mucosa was inspected for the presenceof erythema, lesions, and discharge. Vaginal and cervical swabs samples were obtained and sent to microbiology laboratory.Results: There were 10 in first trimester, 26 in second and 40 in third trimester. The difference was significant (P< 0.05). Clue cells inwet mount was positive in 8 and negative in 68, Nugent’s score >7 was positive in 12 and negative in 64. Amsel’s criteria was positivein 14 and negative in 62. The difference was significant (P< 0.05). Gram’s stain was positive in 5 and negative in 71 and culture waspositive in 11 and negative in 65. The difference was significant (P< 0.05).Conclusion: Bacterial vaginosis was seen in 14 and candidiasis in 11 cases. Diagnosis of vaginal infections was done using both clinicaland microbiological methods.
Renal Lymphangiectasia- Critical Assessment Of A Rare Case And Review Of Literature
Authors: Nishant Raj  , Rajasbala Dhande  , Nikita Bora
Published: November 2022

Renal Lymphangiectasia (RLM) is a very infrequent benign lymphatic disorder. RLM is often misdiagnosed for other disorders suchas cystic renal masses, usually polycystic kidneys. Although parenthetically found in different cases, RLM is a probable cause of renalfailure and hypertension in undiagnosed victims. The etiology of RLM is unclear and results from the formation of cystic masses anddilatation of perinephric lymphatic channels. In the renal sinus, lymphatic channels connect the perirenal tissues and the renal capsulethe kidney’s lymphatic system. Developmental malformation in the above-mentioned channels is one of the hypotheses presumed todescribe the etiopathogenesis of RLM. The other hypothesis presumes the inflammation of the renal perinephric leads to the dilatationand obstruction of lymphatics.
A study of rural clinical practice on efficiency of diabetes education
Authors: Anil Kumar Sharma
Published: November 2022

Introduction: Medication management to monitor blood glucose levels and reduce complications has been the focus of care for thisdisorder. In recent research, however, glycemic regulation enhancement and avoidance of long-term complications have been drivenby self-care behavior.Materials And Methods: This method was used to remove certain cases where diabetes screening was conducted using a single HbA1ctest. This criteria may have contributed to the omission of such diabetes cases (i.e., people with diabetes who had not had an HbA1ctest).Results: The first two columns iden- tified the question number and a small description of the question. The table was divided byfrequencies and percent correct pre-intervention and post-intervention answers.Conclusion: This study had similar conclusions as previous research studies identified in the literature. A similar longitudinal designwith a larger sample size has been recommended. Health care provider education serves as a foundation for maintaining and improvingthe health and well-being of persons with diabetes.
Effectiveness of structured teaching programme on knowledge regarding early identification and home care management of Alzheimer’s disease among family of elderly persons at selected hospital
Authors: Deepika.T  , C R Enoch Snowden Rose
Published: November 2022

Aim: A study was conducted to determine the effectiveness of structured teaching programme on knowledge regarding and homecaremanagement of Alzheimer’s disease among family members of elderly persons.Study design: A Quasi experimental design is used this study.Place and Duration of Study: This study was conducted in Dr.Kamakshi Memorial Hospital, Pallikaranai,Chennai it is 300 beddedhospital.The study duration is 2 weeks.Methodology: The researcher used the Non-probability purposive sampling technique. Population is the family members of elderlyclients made distribution between target and accessible population. The sample size was 60 family members in elderly persons.Results:The results of pretest most of them had inadequate knowledge 40(67%), had moderate knowledge 18(30%), had adequateknowledge 2(3%). In posttest the most of them had moderate knowledge 32(54%), had adequate knowledge 22(37%), had inadequateknowledge 6(10%). The study concluded by family members having a Moderate knowledge on Alzheimer’s disease.Conclusion: The study findings revealed there was an increase level of knowledge after the structured teaching programme on familymembers.
Empirical Analysis Of Covid-19 On Brics Nations And Their Impact Positive/Negative On Stock Market Indices
Authors: Prof. Bk Surya Prakasha Rao  , Prof. P. Raja Babu  , Dr. A. Suresh Kumar  , Dr. Deivasree
Published: November 2022

The coronavirus is a novel disease affected across the world. The symptoms are cold and fever. It was invented in December 2019 byChina and is denoted as Covid-19 by World Health Organization (WHO). This disease affected not only humans but also influencedthe stock market and an economic crisis across the world. About 3% effect on the global economy, it was comparatively higher than2008-09. 1.2% and 2.8% were affected by middle Asia and the middle east during 2019-20. The oil export and import countries wereaffected by about 4.2% and 0.7% (IMF, 2020).The stock market is one of the barometers for Post Covid-19 status measurement. The study aims to analyze the infected cases,investigate the stock market indices in BRICS Nations, and find the relations between infected situations and the stock market ofBRICS Nations. This study uses secondary data from the official websites of the World Health Organization, Dashboard fromJanuary 2021-June 2022. Using Multi Regression analysis in the five nations were infected and death cases and stock market indices.This study will be helpful in the present situation, and investors will decide to diversify funds in the profitable sector to acceleratetheir wealth.
Effect Of Adding Sulfur And Glutathione On Some Biochemical Characteristics Of Leaves Of The Tissue Date Palm (Phoenix Dactylifera L.)Berhi Cultivar Under Heat Stress
Authors: Emad Hameed Abdalsamad Alarab  , Aqeel A. S. Al Khalifa  , Eman Abdulale Hantosh AL-Sereh
Published: November 2022

A study was conducted on the effect of heat stress on some biochemical characteristics of the leaves of the tissue date palm variety Berhi and the role of adding sulfur (S) and spraying with glutathione (GSH) in alleviating the damage from heat stress. Five-year-old palm trees of approximately equal sizes were selected and planted in a private orchard south of Basrah Governorate, Iraq. And conducted the same service operations of fertilization and watering.The following treatments were applied to date palm trees, as agricultural sulfur was added at a concentration of (0, 1, and 2) kg/tree, and glutathione at a concentration of (0, 100, and 200) mg/liter as well as their interactions. The results showed that the highest values with a significant effect for the traits (glutathione and chlorophyll) and the lowest value for a significant decrease in the traits (proline, carbohydrates, hydrogen peroxide and MDA) was for treatment (2 kg S x 200 mg/L GSH) recorded (45.92 μmol g-1 and 6.38 mg 100 g-1). and (4.51 μmol g/g, 10.66 mg/gm, 0.62 μmol g, and 1.94 nmol/gm), respectively, compared with the control treatment that recorded (40.10 μmol g/g and 3.36 mg/gm), and (11.19 μmol g/g, 14.02 mg/gm and 1.06 μmol/g. g and 4.27 nmol/g) respectively for the previous treatments. The results of the current study showed that the addition of sulfur and glutathione helped reduce the damage caused by heat stress and improve biological processes and growth.
Estimation Of Interleukin 27 And Interleukin 33 Serum Levels In Iraqi Neonatal Sepsis
Authors: Aliaa Monther Ebrahem  , Sanaa Khudhur Jameel  , Ali Hafedh Abbas
Published: November 2022

Bloodstream infections in neonates are one of the most life-threatening infections in them . In this study, a total of 140 blood samples werecollected from neonates at AL-Batoul Teaching Hospital for Gynecology and Pediatrics in Baqubah/Diyala, their ages ranging from 1 dayto 28 days during the period from November 2021 to March 2022. The samples were subjected to a culture study as well as hematologicaland immunological tests (CRP, measuring the level of IL-27 and IL-33). Out of total cultured samples 45 give a positive blood culture, 45specimens from blood culture negative was chosen to become (control group) to be comparable to positive culture specimens. The resultsof the CRP test showed in the Gram-negative bacteria group, the positive result was 76.92% (10 of 13). In the Gram-positive bacteria group,the positive CRP percentage was 84.85% (28 of 33). While in the control group the positive result was 13.33% (6 of 45) , significantdifferences appeared between the compared groups. The results showed the mean levels of IL-27 in the sepsis patient group and controlgroup were (21.14 ± 1.01 and 14.49 ± 0.34 pg/ml, respectively). also showed the mean levels of IL-33 were in the sepsis patient group andcontrol group (250.28 ± 15.75 and 101.16 ± 3.38 pg/ml, respectively). There was a significant increased level of IL-27 and IL-33 in the sepsispatients’ group compared to the control group.
Evaluation of Natural killer activated receptor NKG2D, Inhibitory receptor KIR2DL1 and soluble ligand MICA in Iraqi patients of Acute myeloid leukemia
Authors: Baan Abdulatif Mtashar  , Zainab Fadhel Ashoor  , Zeyad Ahmed Shabeb  , Bassam Francis Matti
Published: November 2022

Background: AML is a leukemic disease that related to the rapidly myeloid proliferation progenitor cells are transformed and leadingto stop proliferation and self-renewing. AML have many abilities to evading immune system one of them down expression of NK cellsactivating receptors NKG2D which is elaborate in in cooperation innate and adaptive immunities, and occupations as a “principalswitch” in influential the stimulation of natural killer (NK) cells. NKG2D can binds to a various ligand molecule, which are onlyexpressed at small concentration in usual cells but can be increase by a cellular tension response. And the realizing soluble NKG2Dligands MICA which is express by tumor cells and by binding with NKG2D lead to activated NK cells.Patients and methods: This study consists of 30 new diagnosed patients with AML and 24 out of 30 patients follow up at 14 days aftertreatment, 20 healthy looking persons match age and sex as control group. NKG2D detection by Flowcytometry and soluble MICAdetection by ELISA.Results: The NK cells activation receptor down expression in patients of AML as well as increase releasing of soluble ligand MICA.Conclusion: The NKG2D in patients with AML down expression which may due to increase soluble ligand MICA which lead to maskNKG2D receptors. There was relationship between down expression of NKG2D besides releasing soluble ligand MICA.
Isolation And Identification Of Fungi Associated With Walnuts, Almonds, Hazelnuts, Cashews, Pistachios And Peanuts Using Molecular Diagnostics Technique(PCR) In The Local Markets Of Kirkuk Governorate / Iraq
Authors: Zena Najmalden Nooralden  , Epbhm012@uokirkuk.edu.iq
Published: November 2022

The aim of the current study is to Isolation and identification of fungi contaminated with walnuts, almonds, hazelnuts, cashews,peanuts and pistachios using molecular diagnostics (PCR). Nuts samples were collected with an amount of 2000 grams of walnuts,almonds, hazelnuts, cashews, pistachios and peanuts from different locations of the local markets in the city of Kirkuk and intendedfor human consumption for the period. From 15-November-2022 until 20-December-2022.The results of the molecular diagnosisPolymerase Chain Reaction (PCR)of the fungi with a sequence analysis and drawing the genetic tree to compare the isolated anddiagnosed fungi with the global isolates associated with the fungal genera Aspergillus, Penicillium, Rhizopus, Paecilomyces of nuts,Aspergillus flavus species With a percentage of 26.3%, the isolated fungi sequence and prevalence rates were as follows: A.flavus,A.niger, P. aurantiogrise, P. oxalicum, A. fumigatus, Rhizopus stolonifer and Paecillomyces variotti at 26.3%, 19.7%, 15.8%, 13.8%,11.2%, 9.2% and 3.9%, respectively.
Organizational Pedagogical Conditions Of Professional Development Of Pedagogical Staff
Authors: Kholmurodov Azam Shahriyorovich
Published: November 2022

The article deals with the issues of teacher training and retraining, improving the quality of teachers in schools and theircontinuous training, the introduction of a system of continuous methodological assistance, the transformation of the system of teachertraining into a system of continuous professional development, hybrid (mixed) training issues such as its widespread introduction intoeducational practice are covered in detail.
The Role Of Art Exhibitions In The Development Of Cultural Relations Between Uzbekistan And The European Union
Authors: Ismatullayev Farkhodjon Odiljonovich
Published: November 2022

The article analyzes the development of cultural cooperation between the Republic of Uzbekistan and the EuropeanUnion. The author analyzes on the basis of sources that the organization of various exhibitions, especially the Days of Culture, plays animportant role in these relations. At the same time, it has been shown on the basis of evidence that the participation and role ofmuseums in all cultural cooperation events is extremely high. Materials from the Central State Archive were also used effectively inthe article.
Some Aspects Of The Organization And Management Of The Education System In Uzbekistan
Authors: Ibragimova Gulsanam Nematovna  , Akramov Abdumalik Abdumutalovich  , Alimova Gulchehra Kabilovna  , Asrarkhanovaq
Published: November 2022

The ideas, rules, and laws of human education were initially based on stories, pandnoms, written monuments, andfolklore, and later on, they strengthen their position as an independent science.Indeed, our ancestors paid special attention to child education from time immemorial. Imam al-Bukhari, -Isa at-Termizny, Berunny,Az-Zamakhshari, Navoi, Babur, Ogahi, great scientists, writers, virtuous people like Abdurauf Fitrat, Abdulhamid Cholpon, wrotemany works on education. "The City of Virtuous People" by Faro Bey, who is considered the founder of Eastern pedagogy, "QutadguBilig" by Yusuf Khos Hajib, "Mahbub ul-Qulub" by Alisher Navoi, "Nightmare" by Kaikovus, and "Futuvvatnamai Sultani" by VaizKoshfi are proof of this. It is known from history that Eastern pedagogy once flourished. When the German scientist Herler said, "TheEast is the teacher of Europe", he probably meant this period of development.
Floristic Analysis Of The Dendroflora Of The Zamin State Reserve
Authors: Dadayeva G.S.
Published: November 2022

The Zamin State Reserve, located on the western spurs of the Turkestan Range in the upper reaches of the Sangzar River,is the richest region of Uzbekistan in floristic and phytocenotic terms. This reserve, established in 1926, is unique in the number of rareendangered plant species growing in this small area. Juniper forests, in their completeness and richness of tree and shrub species, haveno analogues in our republic. At least 20 plant species have been described from this territory, which is comparable to the most famousflora of Chimgan. List of vascular plants compiled and published by M.G. Popov, N.V. Androsov in 1937, for a long time was almostthe only floristic information throughout the Western Pamirs. In the second half of the 20th century, large-scale floristic studies werecarried out not only in this region, but also throughout the territory of Uzbekistan. In particular, lists of floras of the Chatkal, Nurataand Surkhan reserves were published. Thus, the dendroflora studied by us, richer in the number of plant species, will be a good help forcreating an electronic database of the modern flora of Uzbekistan.
ZnO:CuO Nanocomposite Produced by Laser Ablation in Water for Antibacterial Activity
Authors: Zainab Ali Hrbe  , Muneer H  , Ahmed N. Abd
Published: November 2022

Zinc oxide (ZnO) and copper oxide (CuO) nanoparticles were created using Nd-YAG pulse ablation, and they were subsequently examinedas colloidal solutions. The produced nanoparticles were examined for UV-VIS absorption using transmission electron microscopy (TEM) andFourier transform infrared spectroscopy (FTIR) (TEM). The production of zinc oxide and copper oxide nanoparticles is shown by FTIRcharacterization. the subsequent tests for UV-VIS absorption. According to TEM, the nanoparticle sizes varied from (30) nm for zinc oxide to(40) nm for copper oxide. X-ray diffraction was used to describe the films' structure (XRD)The X-ray showed the monoclinic crystallinestructure of CuO and the hexagonal wurtzite phase of ZnO. Due to their antibacterial properties, copper oxide nanoparticles with a size rangeof 54.35–40.16 nm and zinc oxide nanoparticles with a size range of 36.16 nm were found to display FESM.
Formation Of Patriotic Concepts In School-Aged Children
Authors: D. R. Babayeva  , G. Kh. Jumasheva  , R.SH.Aleyuova  , G. Najmiddinova
Published: November 2022

Education of new thinkers in the current globalization process and society reform requires serious changes in the education system.Among the countries of the world, the Republic of Uzbekistan was one of the first to create conceptual and theoretical foundations forsolving this problem of a universal nature, and it is being systematically put into practice.