bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Messaging on Perceptions of Careers in Veterinary Medicine: Do Gender Stereotypes Matter?
Authors: Morello Samantha L. , Rogus-Pulia Nicole , Branchaw Janet L. , Brauer Markus , Schwakopf Jordan M. , Carnes Molly
Published: June 2021

The veterinary medical workforce is increasingly female; occupational feminization often transfers stereotypes associated with the predominant gender onto the profession. It is unknown whether within veterinary medicine a feminized public image is a possible contributor to the reduction in male applicants to training programs. The influence of stereotypically gendered messaging on how male and female undergraduate students perceive veterinary medicine was investigated in 482 undergraduate students enrolled in five introductory or second-level biology courses. Two short videos introducing the field of veterinary medicine were developed with imagery and language selected to emphasize either stereotypic feminine ( communal) or masculine ( agentic) aspects of the field. Participant groups were randomly assigned one of the two videos (feminine/communal or masculine/agentic) or no video (no exposure). An outcome survey elicited impressions of the field of veterinary medicine and gathered demographic data. There was a significant linear trend of condition on perception of the profession as feminine or masculine and on perception of the activities of a veterinarian as feminine/communal or masculine/agentic. Female participants were significantly more likely to agree that someone of their gender would be valued in the profession. Male participants reported significantly higher self-efficacy scores for performing the tasks of a veterinarian when they viewed the feminine stereotype video. These results demonstrate that gendered perceptions of the field can be manipulated. Intentional gendered messaging should be further explored as one strategy to broaden the talent pool in the workforce by attracting men back to the field.
Impactos do rompimento de barragens no setor de mineração sobre o valor das ações
Authors:   , Garcia José Otávio
Published: June 2021

The general objective of this work was to analyze how the stock market reacts to environmental disasters in mining. The events studied were the two biggest disasters that occurred in iron mining in the last decade (Mariana in 2015 and Brumadinho in 2019), involving the companies Vale and BHP, two of the three largest iron ore miners in the world. An exploratory study of a documental nature was carried out, with a qualitative approach, based on the analysis of data on stock prices on the B3 and NYSE stock exchanges, and from other secondary data sources, including official documents and reports. The research was carried out through two studies. In the first, the historical data of the companies' share values and sectoral indicators in Brazil and in the USA were highlighted and compared. In the second, which differentiates this research from previous works on the theme, the triangulation of a set of analysis techniques (fundamental, graphical and document) was performed to explain the market's behavior. The survey revealed that, even in the face of major environmental disasters, the behavior of companies' stock prices was different than expected. After Mariana, companies recovered fully on the Brazilian and American stock exchanges. However, after Brumadinho, Vale recovered at B3 in the first year after the disaster, but presented losses at the NYSE, observing the influence of the sector's characteristics, the existing competitiveness, the credibility of the companies and the maturity of the market
Clinical Impact of Biliary Candidiasis in Pancreatoduodenectomy: A Series of Cases
Authors: Suárez-Muñoz Miguel Ángel , LC Hinojosa-Arco , JF Roldan-Rua , Chaves GA Carranque , Y Eslava-Cea , Suárez-Muñoz Miguel Ángel
Published: June 2021

Infectious complications play a prominent role in postoperative outcome of pancreatoduodenectomy. The analysis of the microorganisms responsible for these complications has focused on bacteria, and there is little documentation regarding the role of fungi. We present a case series with 8 patients who underwent pancreatoduodenectomy with positive bile cultures for Candida spp., in order to analyse the postoperative outcome.
Servant leadership’s dimensions and deviant workplace behavior: Perspective at five-star hotels in Jakarta Indonesia
Authors: Emilisa Netania , Kusumaditra Rastri
Published: June 2021

This investigation intends to figure out the implementation of servant leadership’s dimensions to deviant workplace behavior. The data utilized in this investigation is primary data, the content of a questioner filled by employees. The sample collection was carried out utilizing the purposive sampling technique and collected 213 samples. The techniques that were used to analyze this investigation are instrumental tests such as validity and reliability and multiple linear regressions with SPSS 25. Servant leadership variables have seven dimensions, which are emotional healing, creating value for the community, conceptual skills, empowering, helping subordinates grow and succeed, putting subordinates first, and behaving ethically. Deviations made against the company as violating existing norms and regulations will threaten the sustainability of the company. The results prove that all the dimensions of servant leadership have a negative significant effect on deviant workplace behavior. It shows that a great supervisor must find out the career objectives of a staff member. This can be accomplished by improving employees to stay to expand and improve, such as preparing practice, unique adventures in terms of ability to enhance personality-character to diminish employee aim to have deviant activities.
Pharmacologie de la kétamine
Authors: Mion G.
Published: June 2021

La kétamine bloque de façon non compétitive les récepteurs canaux N-méthyl-D-aspartate (NMDA). Elle induit une anesthésie particulière, dite dissociative, en activant le système limbique, mais en déconnectant les voies thalamonéocorticales, notamment les aires associatives. La molécule comporte un carbone asymétrique qui explique l’existence de deux énantiomères. L’isomère S(+) ou eskétamine, qui dévie la lumière à droite, bloque trois à quatre fois plus le récepteur NMDA que l’isomère R(-). Il vient d’obtenir une AMM en France et y possède une autorisation temporaire d’utilisation dans l’indication de la dépression réfractaire. La demi-vie de distribution de la kétamine, dix minutes, permet un réveil rapide. La demi-vie d’élimination est de deux à trois heures. Elle est métabolisée au niveau du cytochrome P450 hépatique. La norkétamine est un métabolite actif qui possède 20 à 30 % de l’effet analgésique de la molécule mère et qui explique l’efficacité de l’administration orale. La kétamine exerce peu d’effets dépresseurs cardiorespiratoires. La préservation de la pression artérielle et du débit cardiaque est aussi efficace qu’avec l’étomidate. Elle possède un effet bronchodilatateur et préserve l’oxygénation en maintenant la ventilation spontanée (VS) et la capacité résiduelle fonctionnelle. Une titration prudente en commençant par de très faibles doses (bolus de 2 à 5 mg), augmentées progressivement, permet la sédation en VS, associée au propofol ou au midazolam. Ses effets neurologiques ont été complètement réévalués depuis une quinzaine d’années, et elle n’a plus de raison d’être contre-indiquée chez le cérébrolésé. Ses propriétés analgésiques et antihyperalgésiques sont depuis une vingtaine d’années au centre de son utilisation périopératoire dans le cadre d’une stratégie d’analgésie préventive multimodale, voire du nouveau concept d’OFA (opioid free anesthesia) et dans le traitement de la douleur. Au blocage des récepteurs NMDA qui explique les propriétés antihyperalgésiques, dont l’opposition à l’hyperalgésie induite par les opioïdes, s’ajoutent l’activation des voies monoaminergiques descendantes, un blocage des canaux sodiques, des propriétés antipro-inflammatoires pléiotropes. Il semble qu’une relation dose-effet implique de maintenir une concentration plasmatique efficace (supérieure à 100 ng/ml) par une perfusion continue. Elle est particulièrement indiquée et efficace en cas de douleurs importantes qui ouvrent les canaux NMDA et chez les patients addicts aux opioïdes (use-dependence).
ARTIFICIAL NEURAL NETWORKS FOR PREDICTING THE GENERATION OF ACETALDEHYDE IN PET RESIN IN THE PROCESS OF INJECTION OF PLASTIC PACKAGES
Authors: Nascimento Mauro Reis , Alencar David Barbosa de , Nascimento Manoel Henrique Reis , Monteiro Carlos Alberto
Published: June 2021

The industrial production of preforms for the manufacture of PET bottles, during the plastic injection process, is essential to regulate the drying temperature of the PET resin, to control the generation of Acetaldehyde (ACH), which alters the flavor of carbonated or non-carbonated drinks, giving the drink a citrus flavor and putting in doubt the quality of packaged products. In this work, an Artificial Neural Network (ANN) of the Backpropagation type (Cascadeforwardnet) is specified to support the decision-making process in controlling the ideal drying temperature of the PET resin, allowing specialists to make the necessary temperature regulation decisions  for the best performance by decreasing ACH levels. The materials and methods were applied according to the manufacturer's characteristics on the moisture in the PET resin grain, which may contain between 50 ppm and 100 ppm of ACH. Data were collected for the method analysis, according to temperatures and residence times used in the blow injection process in the manufacture of the bottle preform, the generation of ACH from the PET bottle after solid post-condensation stage reached residual ACH levels below (3-4) ppm, according to the desired specification, reaching levels below 1 ppm. The results found through the Computational Intelligence (IC) techniques applied by the ANNs, where they allowed the prediction of the ACH levels generated in the plastic injection process of the bottle packaging preform, allowing an effective management of the parameters of production, assisting in strategic decision making regarding the use of temperature control during the drying process of PET resin.
BIOE and the Teaching of Physics: inferences from the Critical Theory of Technology
Authors: Ferrasa Ingrid Aline de Carvalho , Feisser Miquelin Awdry , Basniak Maria Ivete , Rutz da Silva Sani Carvalho
Published: June 2021

This article reads from Andrew Feenberg's Critical Theory of Technology, analyzing the International Bank of Educational Objects (BIOE) in Physics teaching, investigating whether the Educational Objects (EO) available in BIOE contemplate a process of teaching and learning that is critical and reflexive and that articulates with one or more pedagogical conceptions linked to its educational objective. For this, the qualitative approach of the documentary type was used for data collection and content analysis to arrive at the results. Thus, we verify that the EO for Physics available in BIOE do not contemplate a critical and reflexive teaching and learning process articulated to one or more pedagogical conceptions linked to its educational objective; it does not broaden the problematization related to educational practices in physics towards the politicization of science and technology, in understanding the implications of an educational technology; and it is absent in the very understanding of human relations with such objects and the systems in which they operate, including the teaching and learning process.
Load Balancing pada Cloud Computing dengan Sumber Daya Terbatas Menggunakan Penggabungan Algoritma ESCE dan Throttled
Authors: Pamungkas Endang Wahyu , Putri Divi Galih Prasetyo
Published: June 2021

Recently cloud computing technology has been implemented by many companies. This technology requires a really high reliability that closely related to hardware specification and management resource quality used. Adequate hardware would make resource allocation easier. On the other hand, resource allocation will be harder if the resources are limited. This is a common condition in a developing cloud service provider. In this paper, a load balancing algorithm to allocate resources in cloud computing environment that has limited resources has been proposed. This algorithm is developed by taking the advantages of the existing algorithms, Equally Spread Current Execution and Throttled. We merge those algorithm without losing the advantages and we try to eliminate the shortcoming of each algorithm. The result shows that this algorithm is able to give a significant improvement in the limited resources environment. In addition, the algorithm also able to compete with the other algorithm in the more adequate resource environment. Based on the consistent results, this algorithm is expected to be more adaptive in different resources environment.
COĞRAFYA ÖĞRETMENLİĞİNİN ÖĞRENCİ TERCİHİ AÇISINDAN YÖK ATLAS VERİLERİNE GÖRE DEĞERLENDİRİLMESİ: MARMARA ÜNİVERSİTESİ ÖRNEĞİ (2016-2020)
Authors: YILMAZ Ali , ÇİFÇİ Taner
Published: June 2021

Bu araştırmanın amacı, Marmara Üniversitesi Coğrafya Öğretmenliği Programını tercih eden öğrencilerin profillerini ve eğilimlerini belirleyerek programın mevcut durumlarından hareketle geleceğe yönelik değerlendirmeler yapmaktır. Araştırmada nicel araştırma yöntemlerinden betimsel tarama modeli kullanılmıştır. Çalışma evrenini 2016-2020 yılları arasında Marmara Üniversitesi Coğrafya Öğretmenliği Programına yerleşen öğrenciler oluşturmaktadır. Veriler, üniversite adaylarının tercih yaparken faydalanmaları amacıyla oluşturulan YÖK Lisans Atlasından oluşturulmuştur. Elde edilen veriler, içerik analizi yöntemi kullanılarak analiz edilmiştir. Verilerin analizinin yapılmasında Excel, ArcGIS ve SPSS paket programı kullanılmıştır. Bulguların raporlaştırılması; frekans, yüzde değerleri ve grafikler aracılığıyla betimsel tarzda yorumlanarak sağlanmıştır. Cinsiyet dağılımında erkek öğrencilerin fazla olduğu, öğrencilerin önemli bir kısmının Marmara Üniversitesi’nin olduğu ilde veya yakın illerde yaşadıkları tespit edilmiştir. Lise türünde, Anadolu Lisesi mezunu öğrencilerin yoğunlukta olduğu, ülke geneli tercih edilme durumunun ve öğrencilerin ilk üç sırada tercih etme oranının azaldığı belirlenmiştir. Bunun yanında öğrencilerin Coğrafya Öğretmenliği Programından daha çok Türkçe Öğretmenliği Programını tercih ettiği sonucuna ulaşılmıştır. Araştırmanın bulgu ve sonuçları göz önüne alındığında, Marmara Üniversitesi Coğrafya Öğretmenliği Programının taban puanları ve taban başarı sıralamalarındaki düşüşün nedenlerine yönelik çalışmaların yapılması önerilmektedir.
METİNSEL MESAJDAN MEKÂNSAL BİLGİYE: COĞRAFYA ARAŞTIRMALARINDA VERİ KAYNAĞI OLARAK SOSYAL AĞ TWİTTER
Authors: OĞLAKCI Burak , UZUN Alper
Published: June 2021

Web 2.0 dönemi ile hızlı bir gelişim gösteren sosyal medya uygulamaları, kullanıcılarına kolay ve erişilebilir biçimde kendi içeriklerini üretme, paylaşma ve başkaları tarafından üretilen içeriklerle etkileşime geçebilme imkanı sağlamıştır. Popüler bir lokasyon bazlı sosyal ağ olan Twitter, içerisinde barındırdığı kullanıcı üretimli içerikler ile çeşitli disiplinlerin dikkatini çekmiştir. Bu içerikler mekânsal bilgileri ile birlikte elde edildiğinde, coğrafya bilimi araştırmaları için önemli bir potansiyel sağlamaktadır. İlgili ağ üzerinde yer alan mekânsal veri çeşitlerini, verilere nasıl erişilebileceğini ve bu verilerin coğrafya araştırmalarındaki önemini irdelemeyi amaçlayan bu araştırmanın yönteminde retrospektif bir yaklaşım benimsenmiştir. Doküman incelemesi ve açık kaynak kod kullanımı da amaca uygun olarak yöntem dâhilinde kullanılmıştır. Twitter üzerinde toplam üç farklı coğrafi-mekânsal meta veri ve bu verilerin kullanıcılara sunulduğu iki farklı JSON nesnesi olduğu belirlenmiştir. İlgili verilere ulaşabilmek için genel olarak tercih edilen üç farklı yöntem ve bu yöntemlerin kullanıldığı çeşitli araştırma ve projelerin var olduğu görülmüştür. Genel olarak, coğrafya bilimi ile ilişkili on üç farklı araştırma konusu için sosyal ağ Twitter üzerinde bulunan veriler önemli bir veri potansiyeli sağlamaktadır. Yine, Sosyal ağ Twitter üzerinde bulunan kullanıcı üretimli içeriklerin ve ilgili yöntemlerin coğrafya araştırmalarında kullanımının; araştırmalar için veri toplama, analiz etme ve görselleştirme süreçlerine katkı sağlayacağı, araştırmalarda ele alınan konuları çeşitlendireceği aşikârdır.
The relationship between functional head impulse test and age in healthy individuals
Authors: Emekci Tuğba , Erbek Hatice Seyra
Published: June 2021

BACKGROUND: fHIT is an easily applicable test battery that indirectly evaluates the vestibulo-ocular reflex (VOR) from a functional perspective. AIMS/OBJECTIVES: The aim of this study was to Individuals determine the correlation between age and the percentage of correct answers (%CA) obtained in the functional head impulse test (fHIT) in healthy individuals. MATERIAL AND METHODS: A total of 105 volunteers, 50 males and 55 females, between the ages of 18 and 70 years, participated in the study. A Beon Solution fHIT system (Zero Branco (TV), Italy) was used in the study. RESULTS: In our study, a decrease in the mean %CA was observed in all semicircular canals (SCCs) with increasing age. Between age and mean %CA, a significant negative moderate (–0.311) correlation was observed in lateral SCCs, and a significant negative low (–0.257) correlation was observed in posterior SCCs (p < 0.05). In anterior SCCs, there was no statistically significant relationship between age and mean %CA (p > 0.05). CONCLUSIONS: The present study performed in a healthy population will be helpful in terms of making comparisons in studies to be conducted in various vestibular diseases. It will also be a guide for identifying pathological consequences in vestibular diseases.
A Review on Phyto-pharmacological Significance of Ajwa pits (Phoenix dactylifera L.)
Authors: Amir Anam , Ansari Imama , Arif Fasiha , Bano Sughra , Amir Fariha , Ahmad Umair , Raza Ali
Published: June 2021

Phoenix dactylifera L. (Ajwa date) is a natural plant that belongs to the Arecaceae family and consumed as a fruit. It is cultured all over the world especially in desert areas like Arab regions and has nutritional significance and pharmacological values. P. dactylifera L. dominates itself from other dates because of its enrichment in dietary fibers, vitamins, minerals and sugars. The study exhibits that P. dactylifera L. contains certain phytochemicals including phenols and flavonoids which act as antimicrobial agents. The distinctive profile of phytochemicals in P. dactylifera L.is the reason for its frequent use as a medicinal plant. In vivo and in vitro studies have been performed to understand the complete nature of P. dactylifera L. This review article gives an overview of the nutritional significance, pharmacological actions, life stages and phytochemical mechanism of P. dactylifera L.
Production of Extracellular Protease from Bacterial Co-cultures using Solid State Fermentation
Authors: Sheikhs Nabiha Naeem , Qurat-ul-ain  , Saba Altaf
Published: June 2021

Proteases (also known as peptidases or proteinases) are hydrolytic enzymes that cleave proteins into amino acids. They comprise 60% of the total industrial usage of enzymes worldwide and can be obtained from many sources. The current study aims to isolate and screen protease-producing bacterial strains from the soil and to produce protease from the bacterial co-cultures using solid-state fermentation (SSF). Primary screening of the protease-producing bacterial strains was carried out on skim milk agar and they were sub-cultured and preserved on the nutrient agar for further testing. Thirty-two compatibility tests of twenty-seven bacterial isolates were performed and SSF was carried out. Afterward, absorbance was taken at 660 nm against tyrosine as standard. According to the results, the bacterial co-culture 19 showed the highest absorbance with an enzyme activity of 10.2 U/ml. The bacterial strains of the co-culture 19 were identified through morphological and biochemical tests. Bacterial strain 1 was observed as cocci and irregular, while bacterial strain 2 was bacillus and rod-shaped. Both strains were positive for gram staining, catalase test, casein hydrolysis test and methyl red test. As for endospore staining, bacterial strain 1 was spore forming while bacterial strain 2 was a non-spore former. It was concluded that the bacterial co-culture 19 can act as a potent co-culture for protease production. Compatibility test was carried out to enhance the production of protease by utilizing cheap and readily available agro-waste products, which benefit the industry by being cost effective and the environment by being eco-friendly.
The Health Assessment of Vultures (Gyps bengalnesis) From Changa Manga, Lahore: A case Study
Authors: Ghafoor Mafia , Khan Muhammad Asif , Ramzan Amera , Abbas Syed Hassan
Published: June 2021

Vultures are considered as an important indicator of a healthy environment, and they play a vital ecological role as scavengers. The present study was designed to estimate the health of critically endangered Gyps bengalensis in Changa Manga, Lahore, using a technique that does not require drawing blood. Fecal matter of seven pairs were examined and analyzed for protozoan or helminth infections. Gross examination involved checking consistency and color of feces, presence of blood in feces and gross parasites. Obtained samples had different colors and consistency but no blood was found in them. Pair 1 was infested with oocytes, but in pairs 5 and 6 only males were infested, while the female was infested in pair 7. Pair 2, 3, and 4 was completely healthy. Gram staining was also performed to assess the presence or absence of bacteria culture in digestive tracks of Gyps bengalensis. All pairs were infected with either gram positive or negative except Pair 5 which was negative for all gram staining. The present work introduced a technique to assess the health of vultures without drawing blood samples, a process that causes disturbances to their life cycle.
Herpesvirus role in male infertility
Authors:   Federal Research and Clinical Center of the Federal Medical Biological Agency, Moscow, Russian Federation, Kovalyk V.P. , Gomberg M.A. ,   Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology, Moscow, Russian Federation, Bragina E.E. ,   A.N. Belozersky Research Instituteof Physico-Chemical Biology MSU, Moscow, Russian Federation, Yurlov K.I. ,   National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya, Moscow, Russian Federation, Kushch A.A. ,   National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya, Moscow, Russian Federation
Published: June 2021

Nowadays, the search for etiopathogenetic factors of infertility is an urgent medical and social task. 23 men with chronic abacterial prostatitis in a barren marriage underwent the follow-up. Herpesviruses of types IV–VI were detected in urogenital samples (urethra, ejaculate, prostate secretions) in 8 of 23 men who were treated with valacyclovir (500 mg 2 times a day for 3 months) and interferon α-2b in combination with antioxidants — vitamins E and C (rectal suppositories). Based on the personal experience of the authors, the patients were prescribed the following drug use regimen: 3 million IU twice a day — 10 days, then 3 million IU twice a day — 3 times per week for the next 3 weeks. The remaining 15 patients without any detected viruses were prescribed the following: levofloxacin 500 mg — 30 days, tamsulosin 0.4 mg — 90 days, diclofenac 50 mg — 10 days. By the end of therapy, electron microscopy and virology showed a decrease in the concentration and number of virus-positive urogenital samples, as well as a decrease in the number of spermatozoa with viral capsids. Within 6 months from the therapy initiation, the onset of pregnancy was observed in the married couples of 6 out of 8 men with herpesviruses vs. in 4 out of 11 without viruses (p=0.026). Thus, we obtained the data on the role of herpesviruses of types IV–VI in male infertility. A good reproductive effect was achieved with valacyclovir and interferon α-2b in combination with antioxidants in most patients. KEYWORDS: herpesviruses, Epstein-Barr virus, cytomegalovirus, human herpes virus type VI, male infertility. FOR CITATION: Kovalyk V.P., Gomberg M.A., Bragina E.E. et al. Herpesvirus role in male infertility. Russian Medical Inquiry. 2021;5(3):123– 129. DOI: 10.32364/2587-6821-2021-5-3-123-129.
Acute and recurrent cystitis. Difficult patient
Authors:   International Medical Center ", Tsareva A.V. ,   Multi Clinic",   , Tomsk, Russian Federation
Published: June 2021

Urinary tract infections (UTIs) are among the most common infectious diseases that tend to recur and significantly worsen the life quality of patients with acute and recurrent cystitis. Modern clinical guidelines regulate the procedure for diagnosis and the main therapeutic algorithms in bacterial cystitis. Compliance with these guidelines allows doctors of different specialties to exclude neurological diseases manifested by urination disorders and prescribe adequate therapy. The article presents two clinical cases of patients treated with a dietary supplement containing a combination of Cran-Max Cranberry, D-mannose and vitamin D3. In a patient with viral cystitis associated with COVID-19, treatment with this dietary supplement allowed to stop dysuria and significantly improve the clinical condition. In another case, this dietary supplement proved to be a safe and effective method to solve the problem of recurrent infectious and inflammatory diseases of the urinary system. KEYWORDS: acute cystitis, recurrent cystitis, diagnosis of cystitis, dysuria, COVID-19-associated cystitis, antibiotic resistance. FOR CITATION: Tsareva A.V. Acute and recurrent cystitis. Difficult patient. Russian Medical Inquiry. 2021;5(3):130–133. DOI: 10.32364/2587- 6821-2021-5-3-130-133.
Treatment of soft tissue injuries
Authors:   Novosibirsk State Medical University, Novosibirsk, Russian Federation, Zhukov D.V. , Ustikova N.V. ,   Novosibirsk Research Institute of Traumatology and Orthopedics named after Ya.L. Tsivyan, Novosibirsk, Russian Federation, Prokhorenko V.M. ,   Novosibirsk State Medical University, Novosibirsk, Russian Federation,   Novosibirsk Research Institute of Traumatology and Orthopedics named after Ya.L. Tsivyan, Novosibirsk, Russian Federation
Published: June 2021

Background: soft tissue injuries accompany the patient's life and make up the main number of visits to primary health care facilities. As a rule, contusions occur when falling or hitting hard objects and are inherently associated with pain. Aim: to determine the analgesic therapy efficacy for soft tissue injuries of the upper and lower extremities. Patients and Methods: a pilot prospective comparative study was conducted including 54 subjects aged 25–50 years (27 patients with shoulder contusion and 27 with hip contusion). Contusions in all patients were characterized by the formation of subcutaneous or intradermal hemorrhage and soft tissue edema without muscle damage. 8 groups were formed to assess the efficacy of the tablet and injection administration types of ketoprofen and diclofenac, depending on the location of the injury. The time of analgesic effect onset on the 1st day after the injury and the trend of pain severity were evaluated using a visual analog scale, as well as edema severity. Treatment and follow-up of patients were discontinued when a persistent analgesic effect was achieved and the function of the limb was restored. Results: the patients' median age was 44.7 years. The ratio of men and women was 1:1. A feature of the pain syndrome assessment during the initial treatment was that patients with a shoulder contusion rated pain 2-3 points higher than patients with a hip contusion. In the upper limb contusions, ketoprofen in tablets activated already at the 10th minute, in the lower limb contusions – at the 20th minute. The drug injectable form provided a pronounced analgesic effect already at the 5th minute. Both the tablet and injectable forms of ketoprofen demonstrated a benefit over diclofenac. By the 3rd-4th day, it was possible to achieve complete pain relief in all cases. Conclusion: this pilot study confirmed the efficacy and rapid onset of the ketoprofen analgesic effect in the treatment of soft tissue injuries. KEYWORDS: contusion, soft tissue, pain, analgesic therapy, ketoprofen, diclofenac. FOR CITATION: Zhukov D.V., Ustikova N.V., Prokhorenko V.M. Treatment of soft tissue injuries. Russian Medical Inquiry. 2021;5(3):145–149. DOI: 10.32364/2587-6821-2021-5-3-145-149.
Risks of perioperative complications in patients of older age groups: causes, mechanisms and prognostic possibilities
Authors:   National Research University «Belgorod State University», Belgorod, Russian Federation, Trotsyuk D.V. ,   Saint-Petersburg Medico-Social Institute, Saint-Petersburg, Russian Federation, Medvedev D.S. ,   I.I. Mechnikov North-Western State Medical University, Saint-Petersburg, Russian Federation,   Research Institute of Hygiene, Occupational Pathology and Human Ecology, of the Federal Medical-Biological Agency, Saint-Petersburg, Russian Federation, Zaripova Z.A. ,   I.P. Pavlov First St. Petersburg State Medical University, Saint-Petersburg, Russian Federation, Chikov A.E. ,   Research Institute of Hygiene, Occupational Pathology and Human Ecology, of the Federal Medical-Biological Agency, Saint-Petersburg, Russian Federation
Published: June 2021

Age-related changes in the body and concomitant somatic pathology can have a significant impact on the body adaptation processes to operational stress, which is associated with the development of adverse events in the intraoperative period, postoperative complications and long-term prognosis. Both the initial state of the body and the severity of changes in metabolism in response to operational stress, as well as the involvement degree of the body functional reserves, are important. Traditionally used methods for risk stratification, based on a patient’s survey or assessment of his daily activity, do not always provide a comprehensive, objective assessment of the body functional capabilities, especially in patients of older age groups. The prognostic value of cardiopulmonary exercise testing for determining the indications and the risk of complications in various types of surgical interventions has been proved. Based on the results of preoperative cardiopulmonary exercise testing, it is possible to make a more complete, comprehensive assessment of the patient’s body functional status, which is especially important for polymorbid patients. However, at present, there are no clearly defined normative limits for the indicators of cardiopulmonary exercise testing for patients of older age groups, which determines the future prospects for studying the use of this method for patients over 60 years of age with various pathological conditions. KEYWORDS: aging, operational stress, adaptation, functional reserve, prognosis, age-related features, cardiopulmonary exercise testing. FOR CITATION: Trotsyuk D.V., Medvedev D.S., Zaripova Z.A., Chikov A.E. Risks of perioperative complications in patients of older age groups: causes, mechanisms and prognostic possibilities. Russian Medical Inquiry. 2021;5(3):150–155. DOI: 10.32364/2587-6821-2021-5-3-150-155.
Successful surgery for profuse bleeding from Meckel’s diverticulum in a patient decompensated hepatic cirrhosis
Authors:   Samara State Medical University, Samara, Russian Federation, Katorkin S.E. , Bystrov S.A. ,   Samara State Medical University, Samara, Russian Federation, Andreev P.S. ,   Samara State Medical University, Samara, Russian Federation, Shestakov E.V. ,   Samara State Medical University, Samara, Russian Federation, Nazarov R.M. ,   Samara State Medical University, Samara, Russian Federation, Lisin O.E. ,   Samara State Medical University, Samara, Russian Federation, Andreev I.S. ,   Samara State Medical University, Samara, Russian Federation
Published: June 2021

Meckel’s diverticulum is an important issue of modern surgery due to challenges in the diagnosis of its complications. Among them, intestinal bleeding is estimated at 5%. A man with gastrointestinal bleeding of unknown cause was urgently admitted to the surgical department of the Samara State Medical University. Previously, the patient was diagnosed with chronic hepatitis C and decompensated hepatic cirrhosis. Blood tests revealed reduced hemoglobin and RBC, increased WBC, ALAT, and ASAT, and abnormal coagulation. Abdominal ultrasound revealed enlarged liver and intraperitoneal fluid. Esophagogastroduodenoscopy and colonoscopy failed to identify any source of bleeding. Medical therapy was ineffective. Considering recurrent intestinal bleeding, the patient underwent laparotomy. After the dissection of the ileum, a vein of the submucosal layer of Meckel’s diverticulum with fresh blood coming from a defect was detected. Resection of the ileum with diverticulum was performed, intestinal anastomosis was constructed. The postoperative outcome was good. The patient was discharged with relevant recommendations. This observation is rather uncommon. Published papers describe only single cases of intestinal bleedings in patients with decompensated hepatic cirrhosis. KEYWORDS: Meckel’s diverticulum, hepatic cirrhosis, profuse intestinal bleeding, resection of the ileum. FOR CITATION: Katorkin S.E., Bystrov S.A., Andreev P.S. et al. Successful surgery for profuse bleeding from Meckel’s diverticulum in a patient decompensated hepatic cirrhosis. Russian Medical Inquiry. 2021;5(3):162–164. DOI: 10.32364/2587-6821-2021-5-3-162-164.
Procedimentos sanitários operacionais aplicados à abatedouro-frigorífico de Jacaré-do-Pantanal (Caiman crocodilus yacare)
Authors:   Faculdade Qualittas, Sousa Juliana Gomes de , Raimundo Isabela Tosta ,   Universidade Estadual Paulista, Sartori Diego ,   Universidade de São Paulo, Souza Bruna Maria Salotti de ,   Universidade Federal de Minas Gerais
Published: June 2021

The objective of the work was to identify and describe the operational sanitary procedures (OSP) applied in the slaughterhouse of the Pantanal alligator, as well as the possible corrective actions for non-conformities that may be found during the process, in order to reduce or eliminate cross-contamination. Once the alligator slaughter production flowchart was known, it was possible to identify six control points: bleeding, skinning, evisceration, toilet, washing the carcasses and cooling. The OSP refers to a preventive program, as well as the other self-control programs, which must be executed based on preventive measures, thus avoiding possible non-conformities.
Il primato delle istituzioni nella riforma della Pac
Authors: Albisinni Ferdinando , Sorrentino Alessandro
Published: June 2021

- Recent years have seen dramatic and continuous reforms of the European discipline of agriculture, both in the first and in the second pillar, in significant connection with the enlargement of the EC to new member States. The process, still far from being completed, concerns many disciplinary areas, including: economics, governance and distribution of powers, as well as relations among individuals. The result is a new model of "plural" regulation, a "flexible droit" as defined with a suggestive imagine by a French author (Carbonnier). This contributions aims to analyse: the influence of reformed Cap on the institutional framework and the governance model of an enlarged Europe in a world market. A prominent character of the reform has been the marked "renationalisation" in domestic implementation of Cap, with the introduction of several policy options having significant distributional implications. Member States have wide margins of manoeuvre to link financial support to subjective and objective prerequisites and to direct benefits towards selected beneficiaries. This flexibility determines a mise en ouvre not uniform in the Member States, with relevant differences with respect to the recent past. Subsidiarity, Complementarity, Partnership, Non-Discrimination, Fair Cooperation have an impact both on the substance of the choices as well on the distribution of competences and powers among public and private actors at national, regional, and local levels. The outcome brings forward an European discipline of agriculture, which is common for Member States but not necessarily uniform. National choices, even in a strongly decoupled frame, might affect the "equal treatment between farmers" as well as "market and competition". But what is the real economic and political meaning for "equal treatment between farmers" as well as for "market and competition"? and how such concerns are related to the specific CAP concerns within a whole objective function? Tentative answers to these questions may come from the comparative analysis, both economic and juridical, of the Institutions of European agriculture, at common, national and local level. Parole chiave: istituzioni, autonomia, diritto comune europeo, leale collaborazione, sistema di governo. Key words: institutions, autonomy, common European law, fair cooperation, governance.
I controlli sulla circolazione dei prodotti alimentari
Authors: Babuscio Teresa
Published: June 2021

- Food controls are a key issue within the European food safety arena. Since 2002 the legislator is constantly improving the control system in order to better achieve the high safety principles contained in the European regulation n.178 and the network set up in it. Thus, the regulation n. 882/2004 is specifically dedicated to food safety controls: it is the main piece of legislation concerning this aspect as it has been adopted by the co-decisions procedure which involves the European Parliament and the Council. Despite that, it left some "white" spaces to be filled by the implementing measures adopted within the so called comitology procedure in which it is the Commission to act as a co-regulator. The latter is currently implementing art. 15.5. of the regulation n. 882/2004 to set up a system of increased controls for food and feed. Key words: food safety; control system; regulation n. 882/2004.
Produzioni di qualitĂ e sviluppo rurale: il caso polacco
Authors: Szymecka Agnieszka
Published: June 2021

L'oggetto del presente lavoro sono le condizioni giuridiche di sviluppo delle produzioni agroalimentari di qualitĂ  in Polonia. Questo tipo di produzioni Ă¨ molto importante per l'agricoltura europea. Infatti, la Commissione europea considera tali produzioni l'arma piĂą potente degli agricoltori europei in un mondo sempre piĂą competitivo. Esse contribuiscono, inoltre, allo economico-sociale e ambientale sviluppo rurale sostenibile. Nella prima parte l'autrice prende in esame la definizione della "qualitĂ ". Ne analizza varie nozioni adottate dal recente Libro verde sulla qualitĂ  dei prodotti agricoli e sottopone a critica alcune di loro. Vengono presentati anche gli "schemi di prodotti di qualitĂ " europei e nazionali. La seconda parte del lavoro prensenta diverse iniziative avviate in Polonia e dirette alla promozione delle produzioni agroalimentari di qualitĂ . Sono presentate le barriere normative in merito che riguardano: la definizione giuridica dell'attivitĂ  di trasformazione dei prodotti agricoli, le norme fiscali e le regolazioni sulla vendita diretta. Viene fatta una comparazione con le rispettive norme e regolazioni italiane. In conclusione l'autrice constata che il legislatore polacco non Ă¨ sufficientemente coinvolto nella creazione di un appropriato contesto normativo necessario per lo sviluppo delle produzioni di qualitĂ  in Polonia.
Le etichette degli alimenti Ogm
Authors: Bruno Francesco
Published: June 2021

In Europa i prodotti GM o contenenti Ogm, o quelli ottenuti a partire da Ogm, che sono stati autorizzati sulla base della direttiva 2001/18/CE o del reg. CE n. 1829 del 2003, sono soggetti a tracciabilitĂ  ed etichettatura secondo le modalitĂ  stabilite nel reg. n. 1830 del 2003. L'etichetta fornisce ai consumatori le informazioni necessarie per una scelta consapevole e in tale meccanismo a tutela dei cittadini ha un ruolo fondamentale il principio di precauzione. Il lavoro analizza le conseguenze delle regole dell'etichettatura degli Ogm sui (difficili) equilibri in seno alla ComunitĂ  internazionale.
La scrittura del caso clinico
Authors: Nicolň Terminio
Published: June 2021

- In questo lavoro viene presentata una riflessione epistemologica sulla scrittura del caso e sulla logica del ragionamento clinico. Gli argomenti vengono articolati e mantenuti in tensione con le questioni sollevate dal cosiddetto "buco dell'Altro". Questo punto d'opacitŕ riguarda l'esperienza psicoanalitica in un doppio versante: da un lato la pratica clinica chiama in causa la posizione dello psicoanalista nel passaggio che va dal principio alla sua applicazione; dall'altro, per l'analizzante, l'incompletezza dell'Altro non si esprime soltanto come un vuoto logico, poiché per il soggetto la questione sorge a causa del reale della pulsione, resto di godimento che non si lascia addomesticare da nessuna parvenza logica. Parole chiave: caso clinico - fenomeno - scrittura - ragionamento clinico - abduzione.
L'economia italiana nei sentieri del capitalismo imprenditoriale
Authors: Corň Giancarlo
Published: June 2021

Questo articolo analizza i problemi della bassa crescita che l'economia italiana ha vissuto nell'ultimo decennio, aggravati da una recessione globale che ha colto la parte piů dinamica del tessuto produttivo in una fase di cambiamenti strutturali. Nella prima parte l'articolo si sofferma su alcune delle possibili cause della modesta dinamica della produttivitŕ, quali la persistenza di dualismi strutturali e geografici nell'economia nazionale, gli effetti della flessibilitŕ del lavoro e degli intensi fenomeni migratori, le specificitŕ del modello di innovazione senza ricerca. Nella seconda parte l'articolo propone una analisi dei diversi percorsi di trasformazione che da anni le imprese hanno avviato per rispondere ai cambiamenti del contesto competitivo. In particolare, l'incremento di qualitŕ e la ricerca di eccellenza nei prodotti e nel turismo, lo sviluppo e l'integrazione tecnologica nell'industria, l'organizzazione internazionale della produzione, la crescita dei servizi innovativi per le imprese e l'affermazione di una economia dei servizi di prossimitŕ collegati alla salute, alla cultura e all'ambiente.
Progettare il processo costituente di un cluster. Il caso del distretto trentino dell'energia e dell'ambiente
Authors: Gurisatti Paolo
Published: June 2021

Questo articolo racconta la storia di una ricerca-intervento realizzata da un gruppo di

, impegnati a sperimentare nuove tecniche di animazione dello sviluppo economico a livello locale. La storia č focalizzata sui problemi incontrati nella fase costituente di un distretto tecnologico in Trentino, dove il gruppo č stato incaricato di promuovere processi di innovazione tra le imprese del settore costruzioni, nel segmento emergente degli edifici sostenibili. Lo studio di caso evidenzia che la nascita di un nuovo cluster richiede un elevato livello di imprenditorialitŕ tra i

e non solo tra gli attori privati.
Nuovi piani paesistici, un po' indisciplinati
Authors: Cinŕ Giuseppe
Published: June 2021

L'autore si propone di approfondire se e come i nuovi piani paesaggistici in formazione, a seguito delle innovazioni introdotte dal Codice, stiano approdando verso una maggiore operativitŕ rispetto ai piani della generazione Galasso. Questo possibile esito viene esaminato su un campione di tre piani, espressivo dell'estrema varietŕ delle situazioni presenti, e con riferimento ad alcuni aspetti rilevanti nella formazione della disciplina: la copianificazione, la cogenza delle norme, le linee guida, i progetti strategici.
Prospettive per il governo dei bacini idrografici
Authors: Zazzi Michele
Published: June 2021

Il saggio individua alcune prospettive rilevanti per il governo dei bacini idrografici nel rinnovato rapporto tra pianificazioni di settore e auspicata pianificazione integrata del territorio. Le esperienze in corso nei bacini idrografici italiani permettono di enucleare almeno due elementi propulsivi: un'estensione del ruolo di governo delle autoritŕ di bacino, secondo una diffusa esigenza di legittimazione sociale, e una maggiore considerazione per le azioni alla scala locale, solitamente legate alla promozione di opzioni strategiche di sviluppo territoriale.
Miraggi dello sviluppo nel deserto urbano. Community development e weak market cities: due casi studio a Detroit e Pittsburgh
Authors: Coppola Alessandro
Published: June 2021

Oggetto di questo lavoro č l'esame e l'analisi di due casi di community development in altrettante weak market cities: Detroit e Pittsburgh. A essere restituiti sono la funzione, la cultura e le iniziative di attori della cosiddetta Community development industry (Cdi) negli Usa - di cui, in precedenza, si presentano sinteticamente nascita ed evoluzione - nelle due cittŕ. Nelle conclusioni, l'autore critica limiti e incongruenze di una strategia di mercato nel trattamento dei "quartieri deprivati" nelle weak market cities.
Sviluppo della visione nei prematuri: uno studio elettrofisiologico
Authors: Ruberto G. , Angeli R. , Guagliano R. , Barillŕ D. , Signorini S. , Fazzi E. , Antonini M. , Bianchi P.E.
Published: June 2021

- Negli ultimi decenni lo sviluppo delle metodiche elettrofunzionali ha permesso di determinare in maniera oggettiva e sufficientemente precisa l'evoluzione visiva nei primi anni di vita. Nel presente lavoro viene descritto uno studio condotto su 92 nati a termine e 29 nati pretermine (tra 28 e 35 sett. di Etŕ Gestazionale). Tutti i soggetti sono stati sottoposti a valutazione elettrofisiologica con PEV flash, PEV pattern transient di tipo reversal, PEV pattern di tipo steady-state; tali esami sono stati praticati 2 volte (a 3 ed a 8 mesi di vita) nei nati a termine e 4 volte (a 3 mesi post-natali, a 3 mesi di etŕ corretta, a 8 mesi post-natali, a 8 mesi di etŕ corretta) nei prematuri. I risultati confermano l'utilitŕ degli esami elettrofisiologici nello studio della maturazione neurovisiva del prematuro.

Parole chiave: maturazione visiva, potenziali evocati visivi da flash (f-PEV), potenziali evocati visivi da pattern transient (p-PEV), potenziali evocati visivi da pattern steady-state (ss-PEV), elettroretinogramma
Comunicare la diagnosi di minorazione congenita
Authors: Cannao M.
Published: June 2021

- Vengono prese in esame le reazioni dei genitori alla diagnosi di minorazione congenita del figlio, con specifico riferimento alla minorazione visiva (cecitŕ o ipovisione). Di tali reazioni, inevitabilmente connotate da grande sofferenza, č necessario tener conto quando si comunica la diagnosi, in modo da aiutare i genitori a superare il trauma e riattivare in loro la fiducia e la speranza. Affinché ciň sia possibile la comunicazione deve essere concepita come tappa iniziale di un processo di aiuto da prolungare per tutto il periodo di degenza ospedaliera della madre e del neonato e anche dopo la dimissione. I protagonisti di questo processo sono sia il medico (al quale spetta il compito dell'informazione clinica) sia tutti gli altri operatori sanitari (che devono fornire un costante sostegno), sia i genitori stessi. Una diagnosi comunicata con rispetto, partecipazione, solidarietŕ, competenza, prepara il terreno per la costruzione del legame di attaccamento con il figlio minorato e risparmia ai genitori l'ulteriore sofferenza di non sentirsi compresi e accolti in una delle fasi piů drammatiche della loro vita.

Parole chiave minorazione congenita, cecitŕ, ipovisione, diagnosi, comunicazione
Misura di partecipazione
Authors: Turconi A.C. , Stefanoni G.
Published: June 2021

- Nel presente lavoro vengono descritte le scale di misura della partecipazione che documentano l'autonomia e il grado di indipendenza funzionale del soggetto. Sono inoltre presentati alcuni strumenti di misura di soddisfazione e qualitŕ della vita del soggetto e della sua famiglia.

Parole chiave: partecipazione, performance, autonomia