bluuebunny/crossref_metadata_2025 huggingface dataset:
Challenges and facilitators for health practitioners and academics engaging in collaborative research and publication: A systematic review / Herausforderungen und Förderfaktoren für gemeinsame Forschung und wissenschaftliche Publikation von Angehörigen verschiedener Gesundheitsberufe aus Praxis und Forschung: ein systematischer Review
Authors: King Lindy , Zlatanovic Tatjana , Gillham David
Published: November 2019

Introduction

While academics are frequently engaged in research activities and subsequent dissemination of results through publication, all too often they occur without health practitioner involvement. While there are contemporary expectations that health practitioners will be active contributors to their discipline’s body of knowledge, many find it difficult to prioritise research involvement given the demands of direct patient care. With this awareness as a central focus, we undertook a literature review to identify the challenges and facilitators that impact on health practitioners and academics working collaboratively on research and publishing their findings in peer-reviewed journals.

Methods

A configurative systematic review was performed with six electronic databases (Proquest, CINAHL, Medline, ScienceDirect, ERIC, SocINDEX) searched for studies from the disciplines of nursing, social work, allied health professions, health management, psychology and sociology. Manual searches were also undertaken to minimise the risk of missed studies. A rigorous search and retrieval process identified 20 relevant studies for inclusion in the review. The studies were first critically appraised then summarised. These steps were followed by thematic synthesis of the findings of the reviewed studies.

Results

Challenges and facilitators to health practitioners and academics working collaboratively on research activities were found to be related to the interplay between practitioners, academics, educational and health institutions and professional demands. The interplay of these factors emerged as complex.

Conclusion

Strategies have been recommended that may encourage active partnerships between institutions, health practitioners and academics enabling greater research collaborations and subsequent increased publication of their combined achievements.
Views of practice owners on intraprofessional cooperation in teams of professionally trained and academic therapists / Sichtweisen von Praxisinhabern/-innen auf die intraprofessionelle Zusammenarbeit in Teams von berufsfachschulisch ausgebildeten und akademisierten Therapeuten/-innen
Authors: Schönfeld Andreas , Luderer Christiane
Published: November 2019

Background

The academisation of the therapy professions occupational therapy, speech therapy and physiotherapy in Germany has created new challenging constellations. Tensions can be seen in the intraprofessional cooperation of professionally qualified employers and academic employees due to identical work contents and equal pay.

Question

How do professionally trained leaders experience the intraprofessional cooperation of professionally trained and academic employees?

Aim

The study describes from the point of view of professionally trained therapists their experiences in their daily work with academic employees in order to derive opportunities, challenges and success factors in intraprofessional cooperation.

Method

A qualitative content analysis with computer support in MAXQDA of n=9 semi-structured focussed interviews from a two-arm cross-sectional study with extern method triangulation is presented. The data are supplemented by n=85 free text entries of two online surveys.

Results

The interviewed leaders welcome academisation because of the promotion of professional stability, social recognition and the advancement of research. In the intradisciplinary cooperation with their academic colleagues there is a predominantly friendly and equal working atmosphere. However, interviewees report a limited creativity of academic employees in practical work, as well as fluctuations with unsatisfying practical commitment due to a low occupational perspective and poor remuneration.

Discussion

While academic employees are eager to expand their practical work, this can only be achieved by providing time and financial resources from practice management. Structural incentives must be provided by more responsibility, extended fields of activity or qualification and performance-related remuneration models in order to retain academic employees in practice.While academic employees are eager to expand their practical work, this can only be achieved by providing time and financial resources from practice management. Structural incentives must be provided by more responsibility, extended fields of activity or qualification and performance-related remuneration models in order to retain academic employees in practice.
Development of Information Models for Increasing the Evaluation Efficiency of Wireless Channel Parameters of 802.11 Standard
Authors: Mykhalevskiy D. M. , Kychak V. M.
Published: November 2019

The objective of the research is to develop information models in order to improve the efficiency of evaluating the parameters of the wireless channels in 802.11 standard. A feature of the information model of the wireless channel of 802.11 standard is an opportunity to evaluate the efficiency of transferring the information block taking into account the complete packet and frame transmission cycle in the event of errors in frames. In addition, the model accounts for the existence of other subscribers in the network and the mechanism of competition for the physical resource of the frequency channel. It has been established that channel efficiency is mostly affected by the presence of destabilizing factors in the channel, which lead to an increase in the number of service information and an increase in the transmission cycle due to the creation of reciprocal queries.
Optimization of the Selection Method for Reconstruction of Outworn Gas Distribution Pipeline
Authors: Koposovs A. , Bode I. , Zemite L. , Dzelzitis E , Odineca T. , Ansone A. , Selickis A. , Jasevics A.
Published: November 2019

Currently, problems related to the operation and exploitation of safe gas distribution networks are deepening in Latvia and Eastern Europe, as the number of outworn underground gas pipelines is steadily increasing. It should be noted that there is a rather wide choice of technology and materials for gas distribution pipeline reconstruction, while at the same time there is no universal method that equally meets all possible work requirements. Therefore, it is an urgent task to understand the operational algorithm, while choosing optimal reconstruction option, classifying and determining the criteria affecting the choice, and determining the scope of each reconstruction method. For this reason, it is necessary to develop a scientifically based methodology for selecting the optimal method for the reconstruction of outworn gas distribution pipelines. Therefore, there are the following tasks that need to be accomplished: to carry out a complex analysis of reconstruction methods and factors determining the choice of an optimal gas distribution pipeline reconstruction method as well as perform the analysis of current state and development of gas supply network; to develop an algorithm for selecting an optimal gas distribution pipeline reconstruction method based on a multi-criteria approach; to develop a mathematical model for the selection of an optimal reconstruction method and scientifically based complex evaluation procedures taking into account technical and economic criteria; to analyse the interaction of the polyethylene gas pipeline with the steel frame during the post-reconstruction process using U-shaped pipe; to develop recommendations for the optimisation of gas distribution network reconstruction programmes. As a result of these tasks, a scientifically justified methodology for the selection of an optimal method for the reconstruction of the gas distribution pipes has been developed.
Mechanisms of Electron Scattering in Uniaxially Deformed Silicon Single Crystals with Radiation Defects
Authors: Luniov S.V. , Lyshuk V.V. , Maslyuk V.T. , Burban O.V.
Published: November 2019

Temperature dependencies for Hall mobility of electrons for the uniaxially deformed n-Si single crystals, irradiated by the flow of electrons Ω=1·1017 el./cm2 with the energy of 12 MeV, are obtained on the basis of piezo-Hall effect measurements. From the analysis of these dependencies it follows that under the uniaxial pressure (0–0.42) GPa and (0–0.37) GPa along crystallographic directions [100] and [111], respectively, the deformation-induced increase of the Hall mobility has been observed. On the basis of the proposed theoretical model of mobility, this increase is explained by the decrease of the amplitude of a large-scale potential with an increase in the magnitude of uniaxial deformation and, accordingly, the probability of electron scattering on this potential. The slight discrepancy between the obtained experimental results and the relevant theoretical calculations at the low temperatures is due to the fact that the electron scattering on the radiation defects, created by the electron radiation, was not taken into account in the calculations. The decrease in Hall mobility of electrons along with an increase in temperature for unirradiated and irradiated silicon single crystals is explained by the growth of the probability of electron scattering on the optical phonons that are responsible for the intervalley scattering in silicon. The obtained results can be used in designing and modelling on the basis of n-Si single crystals of various electronic devices of micro- and nanoelectronics, which can be subject to the extreme conditions of action of the significant radiation and deformation fields.
Multiphase extraction of ephedrine from Pinellia ternata using bionic liquid-modified polymer
Authors: Fang Luwei , Tian Minglei , Lin Liangwen , Row Kyung Ho
Published: November 2019

Multiphase extraction (MPE) was applied as a developed, convenient and efficient method in separation of ephedrine from Pinellia ternata. Firstly, in order to increase the adsorption efficiency, bionic liquid-modified polymer was created. Comparing the effects of all sorbents under variables conditions, the highest amount of 5.8 mg/g can be adsorbed on dual imidazole ionic liquid modified polymer (Im-Im-Poly) in methanol/water (70:30, v/v) solution at 25°C within 30.0 min. Then the Im-Im-Poly was applied in MPE, after 7 times repetition of extraction, around 1.0 mg/g of ephedrine from Pinellia ternata was detected. After washing by water, ethanol and methanol, and elution by methanol/acetic acid (99.0:1.0, v/v), ephedrine was successfully separated.
Treatment of vinasse liquid from sugarcane industry using electro-coagulation/flocculation followed by ultra filtration
Authors: Karchiyappan Thirugnanasambandham , Delcolle Roberta D. , Goncalves Gustavo L. , Vareschini Daniel T. , Gimenes Marcelino L.
Published: November 2019

In this present work, vinasse, a by-product of sugarcane industry, was examined using combined treatment methods to purify it. Electrocoagulation/flocculation, ultrafiltration were applied as pre-treatment and post-treatment, respectively. The effectiveness of combined process was evaluated based on colour, turbidity and chemical oxygen demand (COD) removal. The efficiency of electrochemical reactor was investigated according to process variables such as retention time, electrode distance and electrolyte dose. From the results, the price to treat unit vinasse is found to be 2.5 US$/m3 under optimum conditions. FT-IR analysis of sludge obtained shows the results of electro-coagulation process. Ultrafiltration as post treatment experiments showed the enhanced removal efficiency of colour (91%), turbidity (88%) and COD (85%). The results showed that electrocoagulation followed by ultrafiltration is a suitable combined technique to reduce the colour, turbidity and COD from vinasse liquid.
Loessoid Soils Improvement – Laboratory Tests and Road Engineering Applications
Authors: Nguyen Cong Dinh , Burlacu Catalin , Boti Ioan
Published: November 2019

Moisture-sensitive or collapsible soils are materials with high porosity that under the loads transmitted by the superstructure or even under its own weight present additional settlements once the soil is saturated. This category includes loess deposits and other high silt content soils with uneven porosity. A method often used for foundation on these soils is the realization of local loessoid material compacted columns. This paper presents, on one hand, the experimental laboratory programs aiming to achieve some optimal mixtures of local material (loess) and different other materials (sand, bentonite, cement) in order to improve the values of the mechanical parameters of the soil and so, to limit the settlements. On the other hand, it presents a lot of settlement calculations for different case scenarios.
Study of the Influence of Fibres Type and Dosage on Properties of Concrete for Airport Pavements
Authors: Dicu Mihai , Matei Andreea , Voiniţchi Constantin Dorinel
Published: November 2019

The paper follows the potential practice of fiber reinforced concrete (FRC) as a solution for airport`s runway pavements, in order to increase the bearing strength, resulting in decreasing the height of the concrete layer that is currently used.

Experimentally, the study focuses on the properties of fiber reinforced Portland cement concrete using 3 different percentages (0.5%, 1% and 1.5% of the concrete volume) and 4 different types of fiber (for 1% percentage – hooked steel fiber 50 mm length, hooked steel fiber 30 mm length, crimped steel fiber 30 mm length and polypropylene fiber 50 mm lenght), using as reference a plain concrete with 5 MPa flexural strength.

More exactly, the study presents the change in compressive and flexural strength, shrinkage, thermal expansion factor, elastic modulus and Poisson`s ratio over fiber type and dosage.

For the highest performance concrete (7 MPa flexural strength), it has been made a study using two methods for rigid airport pavements design (general method and optimized method), and one method for evaluation of bearing strength (ACN – PCN method), which is compared to a plain 5 MPa concrete. Furthermore, the decrease in the slab`s thickness proportionally to the growth of the flexural strength is emphasized by evaluating the slab`s height for a high performance 9 MPa concrete using both design methods.
Clinical, Dermatoscopical and Laboratory Essentials of Fish Tank Granuloma
Authors: Dobrosavljević Danijela , Luković Bojana , Brašanac Dimitrije , Kosovac Olivera
Published: November 2019

In immunocompetent individuals Mycobacterium marinum (M. marinum) infection usually presents with localized skin lesions, better known as “swimming pool granuloma” or “fish tank granuloma” (FTG). When establishing the diagnosis of FTG, doctors encounter several problems in the clinical practice: granulomas are detected in less than two thirds of biopsies and acid-fast bacilli are identified only in a minority of cases. Majority of disseminated and aggressive FTG forms are unrecognized at the beginning, and occur in immunosuppressed patients, including organ transplant patients. Functional impairment or even amputation of the extremity, visceral involvement and lethal outcome have been reported. Although more than one thousand cases of FTG have been reported worldwide, dermatoscopy of FTG, as a diagnostic aid, has not been reported yet. Presenting the case of FTG of recent onset where, guided by dermatoscopy, microorganisms were isolated and identified from the biopsy material, we summarize the essentials of clinical and laboratory diagnostics of M. marinum infection.
Design of Reporting, Evaluation, and Monitoring Application for Student Organization Activity in University
Authors: Soesanto Rayinda Pramuditya , Rizana Afrin Fauzya , Andrawina Luciana
Published: November 2019

In few decades, the development of information system has been increased rapidly. It is because most organization in various sector of industries, commerce, government, or even education become highly dependent on the use of the information system. This study aimed to design the application that will facilitate the activities in organization based on what user needs. The object of this study is student affair department in one of faculty in one of the universities in Indonesia. The method employed in this study to design the system is waterfall method. The system designed in this study is the focus for the activities related to student organization activities. The result of this study is there are eight dimensions quality that has to be fulfilled by the system according to the result of focus group discussion and Delphi method. The system designed in this study was adjusted to the needs that have been defined previously.
Relevant changes in the pharmacovigilance system in Russia and the EAEU
Authors: Gildeeva G. N. , Belostotskiy A.V. , Andreeva D.M.
Published: November 2019

The plant of castor is widely spread in the Iraqi land, and characterized with containing ricin toxin, which has a very serious effects, and because the seeds of this plant scattered in the agricultural soil and rivers water , which increases the exposure of humans and animals to these beans. Objective: This experiment was designed to study the effect of high concentration of castor bean powder in some physiological and biochemical parameters and changes in some tissues of the body, as well as trying to use doxycycline to reduce the effects of ingestion of these seeds. Materials and Methods: In the experiment, 24 local rabbits were raised and fed in the Animal House of the Faculty of Medicine / Al-Muthanna University, then divided into four groups and treated for three weeks (21 days), Control group: treated with normal saline solution (0.9) orally throughout the experiment, G1: was treated orally with a concentration of 25 mg / kg of castor bean powder daily during the experiment, G2 : orally treated 25 mg / kg of castor bean and 25 mg / kg of doxycycline, G3: orally treated 25 mg / kg of castor powder with 50 mg / kg of doxycycline daily throughout the trial period. Results: The results of the experiment showed significant changes(p less than 0.05) in all physiological and biochemical blood tests when compared with control group. There was a significant decrease in PCV, Hb, RBC, T.protein and body weights, while demonstrated a significant increase in WBC, Urea, Creatinine, ALT, AST and ALP, with distortions in liver and kidney of animals that treated with Castor beans. In contrast, the treatment with doxycycline and caster beans showed significant improvement reflected by a normal proportions in physiological tests and biochemical tests with improvement in the tissues when compared to control group. Conclusions: It can be concluded from this study that castor bean has high toxic and pathogenic effects that may be dangerous to the life of the organism. Therefore, it is advisable to be cautious of these pills and avoid exposure to them, also recommended to take high concentrations of doxycycline treatment when infected with castor bean poisoning.
Investigation of microbial contamination of Powdered Infant Formula during different storage periods after opening
Authors: Al-atrash Mohammed Khalid
Published: November 2019

The present study was carried out to knowing effect different storage periods of the microbial quality for the Powdered Infant Formula (PIF) after opening the tin, and ensuring from the safety note (after opening, use within 3 weeks). Thirty (30) samples of (PIF) from category (1 – 6 months) in five different types are collected from pharmacies and local markets in Baquba city / Iraq, which are used as substitutes for breast milk during the first day of opening the tin powders such as Total viable count, Total coliform count, Salmonella count and Yeast and Molds count. These experiments repeated at each week of same samples within (5) weeks. Results were obtained at opening the tin, Total viable count (less than 0.05 1.0 x 103 ±1.5x10 CFU/g) were significantly higher than Total Coliform count (less than 0.05 ± 0.3 x 10 CFU/g) and Total Salmonella count (less than 0.05 0 x 10 CFU/g) and Yeasts and Molds (less than 0.05 ± 0.3 x 10 CFU/g). while results obtained at fifth week were (less than 0.05 8.8 x 103 ±5.5x102 CFU/g), (less than 0.05 0.9 x 102 ± 0.4x101 CFU/g), (less than 0.05 0 x 10 CFU/g), (less than 0.05 9.5 x 10 ± 1.2x101 CFU /g) respectively. All samples of (PIF) having non-significant difference. These results compared to Iraqi Quality Standards (IQS), all the results from the opening samples to fifth week were within the range of IQS and USA Environmental Protection Agency (USEPA) and as indicates the hygienic condition of (PIF) without risk level for human health. also observed increase in microbial contamination in each week because increase the moisture content for powdered milk. Can be used more than 3 weeks after opening if stored in good conditions with good hygienic practices during milk preparation.
ANTIBACTERIAL ACTIVITY OF COPPER OXIDE NANOPARTICLES AGAINST METHICILLIN RESISTANT Staphylococcus aureus (MRSA).
Authors: Raheem Haider Qassim , Al-Ghazali Linda H , Al-Marzook Farah A.
Published: November 2019

One hundred wound swab samples were collected from wound patients who visited in the Teaching Hospital wound unit in Hillah, Babylon province, Iraq. S. aureus was identified morphologically and biochemically. Total of 30 (30%) from total samples exhibited positive culture for S. aureus. Out of 30 S. aureus, 8 (26.6%) isolates were MRSA, Antibiotic susceptibility was tested for 8 antibiotics for MRSA that appeared sensitive toward Tetracycline, Rifampin and Ciprofloxacin (62.5%) but (37.5%) were resistant. For PenicillinG and Cefoxitin, all isolates were resistant (100%). For Clindamycin, (25%) of isolates were resistant but (75%) were sensitive. About (62.5%) were resistant to Erythromycin but (37.5%) were sensitive. Isolates showed resistance to Gentamycin in 50% and 50% sensitive. Anti-bacterial activity of copper oxide nanoparticles (CuO NPs) against S. aureus displays excessive widespread spectrum antibacterial action against established bacteria with increase zone of inhibition diameter that is proportional with the increase in nanoparticle concentration. The (MIC of CuO NPs ranged from 75-150μg/ml and the MBC ranged from 150-300μg/ml. CuO NPs is recommended as an efficient anti-MRSA alternative.
Antibacterial Activity and Qualitative Phytochemical Analysis of Cladophora glomerate
Authors: Rassul Ali Rusl Abed Al , Dwaish Ahmed S
Published: November 2019

Filamentous specie of algae (Cladophora glomerata) collected from Baghdad University –Iraq were tested against bacterial species. Extracts of Cladophora glomerata species were prepared in acetone, hot and cold aqueous extracts. four different concentrations (w/vol.) 12.5 ,25 ,50 and 100 mg/ml were made in each of the above mentioned extracts.
Extracts were loaded on agar plates, containing test bacteria, staphylococcus aureus, staphylococcus epidermidis, Bacillus substilis, Escherichia coli, Klebseilla sp. and pseudomonas aeruginosa. Hot and cold aqueous extracts were inefficiency in all bacterial species, while the hot acetone extract was efficiency for making extract that showed good zone of inhibition in bacterial species maximum up to 18 mm than the lower value was 7.5 mm. Chemical analyses showed that the active chemical compounds for hot acetone extract alga (Cladophora glomerata) extract was contains alkaloids, phenols, Tannins, Flavones, Resins and tannins. The acetone extract was further chemically characterized by using GC–MS in order to be tentative identify the compounds responsible for such activities. The main compositions were Methadone, Benzonitrile, bromobutyloxychalcone, Benzeneethanamine and Cyclodecasiloxane compounds which had antimicrobial activity. These results indicate that the acetone extract of C. glomerata exhibited appreciable antimicrobial activity and could be a source of valuable bioactive materials for health products.
Stability Indicating UV Spectrophotometric Method for Estimation of Omeprazole and Its Application to Content Uniformity Testing
Authors: M Biju V , S Naga Gayatri , M Meenu P
Published: November 2019

Omeprazole is a most commonly used antiulcer agent in clinical practices. A least time consuming efficient and simple ultraviolet spectrophotometric method for the assay of omeprazole has been developed. The assay was based on the ultraviolet absorbance maxima at about 217.80 nm wavelength of omeprazole using sodium hydroxide as the solvent. In the present study comprehensive stress degradation was carried out according to ICH Q1 (R2) guidelines. The drug was
subjected to acidic (0.1N HCl), basic (0.1N NaOH), oxidative (1% H2O2), photolytic and thermal degradation conditions. The developed UV spectrophotometric method showed high degradation under acidic condition, moderate degradation under basic, photolytic and thermal conditions. But it was relatively stable under oxidative conditions. The pathway for degradation has been proposed. The method was validated for Linearity, Accuracy, Precision, Specificity, Ruggedness and Robustness. The method shows good linearity in the range of 2-20μg/ml. The LOD and LOQ were found to be 0.1 μg/ml and 1.1 μg/ml. The %RSD was found to be with in limit i.e. less than 2%.The mean recovery of placebo was 100.68%. It can be concluded that the developed procedure is valid and can be applicable for determination of content uniformity for available brands of omeprazole. This method is applicable for the daily routine quality control quantitative analysis of omeprazole.
Cytotoxic Activity of Thymus vulgaris: Antibacterial and Antifungal Activity
Authors: Hameed Imad Hadi , Hussein Hussein J , Hadi Mohammed Yahya
Published: November 2019

Thymol, an antiseptic, is an active ingredient in various commercially produced mouthwashes such as Listerine. The medicinal properties of wild thyme have been extensively used in official and traditional medicine for many years and centuries, respectively. The herb is used in preparations of natural herbal remedies, such as syrups, tinctures, infusions, decoctions, tea, and oil. The increase in multidrug resistant strains of pathogenic microorganisms has led to extensive phytochemical and pharmacological studies of T. vulgaris as an important source of medicinal substances with antioxidant, antimicrobial, antitumor, and cytotoxic properties and their effective medicinal application, as well as use in
pharmaceutical, food, and cosmetic industries. According to the PDR for Herbal Medicines, wild thyme is a component in various standardized preparations with antitussive effects, while alcohol extracts are integral components of drops used
for coughs and colds.
Effectiveness of Fish Oil Containing Omega-3 in Improving Symptoms and Lung Function in Asthma Outpatient in Surabaya, Indonesia
Authors: Lorensia Amelia , Wahyud Mariana , Mayzika Nadia Aisah
Published: November 2019

Indonesia as a potential maritime country in fish production, can be processed into fish oil containing omega-3. Based on previous libraries, omega-3 fish oils can be used to improve asthma control and improve lung function. The effects of a drug are individualized depending on genetic and environmental factors. The aim of the study was to investigate the effect of fish oil containing omega-3 on improving asthma symptoms and improving lung function. The research method used is pre-post test design, using data collection technique with asthma control test questionnaire to see clinical symptoms of asthma and measure lung function with peak flow meter. Intervention given is a fish oil product with once daily doses,then follow up every week for 4 weeks. The subject of research is adult age. Pulmonary function data and asthma symptoms will be tested for normality with shapiro-wilk test and followed by anova one way. The research was conducted in 2016-2017 in Surabaya and the data obtained 28 respondents. At the control level of asthma and total ACT score (P less than 0.05) it can be concluded that there was significant difference between before and after omega-3 fish oil therapy for 4 weeks. In the improvement of lung function there is a significant improvement of lung function starting from before therapy until the increase every week until the 4th week. Fish oil containing omega 3 for 4 weeks may decrease asthma symptoms in the
asthma control level category and total ACT score. In addition, fish oil can also improve lung function significantly in
every week
Molecular Detection of wzx1 and wzy Genes in Multi Drugs Resistance E. coli Isolates
Authors: Al-Terehi Mona , Khazaal Saba Saadoon , Muhammed Haidar J , Behjet Russul Hikmat
Published: November 2019

Escherichia coli have been genetically changes in Iraqi environments, the present study was carried out to detection E coli isolates sero-group using o-antigens gene cluster, tow genes were amplified used multiplex PCR, the results of present study show that present isolates have more than one plasmid in different size (500-700 bp). PCR results show
about 100% of isolates were had a positive results of PCR products of O45 wzx1 gene (451 bp) while 25% of isolates were a positive PCR products of O45 wzy1 gene (255 bp) and about 25% of isolates have tow genes. A new finding in present study that 50% of isolates have other copy of O45 wzx1 gene, these results concluded that it may be important in Iraqi isolates identification and classification however we need more information about genes sequencing.
Predicting NMR Relaxation of Proteins from Molecular Dynamics Simulations with Accurate Methyl Rotation Barriers
Authors: Hoffmann Falk , Mulder Frans , Schäfer Lars V.
Published: November 2019

The internal dynamics of proteins occurring on time scales from picoseconds to nanoseconds can be sensitively probed by nuclear magnetic resonance (NMR) spin relaxation experiments, as well as by molecular dynamics (MD) simulations. This complementarity oﬀers unique opportunities, provided that the two methods are compared at a suitable level. Recently, several groups have used MD simulations to compute the spectral density of backbone and side-chain molecular motions, and to predict NMR relaxation rates from these. Unfortunately, in the case of methyl groups in protein side-chains, inaccurate energy barriers to methyl rotation were responsible for a systematic discrepancy in the computed relaxation rates, as demonstrated for the AMBER ﬀ99SB*-ILDN force ﬁeld (and related parameter sets), impairing quantitative agreement between simulations and experiments. However, correspondence could be regained by emending the MD force ﬁeld with accurate coupled cluster quantum chemical calculations. Spurred by this positive result, we tested whether this approach could be generally applicable, in spite of the fact that diﬀerent MD force ﬁelds employ diﬀerent water models. Improved methyl group rotation barriers for the CHARMM36 and AMBER ﬀ15ipq protein force ﬁelds were derived, such that the NMR relaxation data obtained from the MD simulations now also display very good agreement with experiment. Results herein showcase the performance of present-day MD force ﬁelds, and manifest their reﬁned ability to accurately describe internal protein dynamics.
Writer’s Cramp or Focal Dystonia- Case report of a Rare Neurological Disorder
Authors: Ghalaut P S  , Meenal Babra
Published: November 2019

There are various neurological disorders which are clinically diagnosed and treated every day. Focal dystonia's such as Writer’s cramps or musician’s cramps is one such neurological disorder that is not very common, but if remains undiagnosed or not treated appropriately causes severe disability and anxiety to the patient. It not only hampers them emotionally and socially but also leads to professional problems. There are various treatment modalities available. Patients complain of spasm or cramping of muscles, which is sometimes associated with pain and inability to write or play an instrument which he/she used to play perfectly some time ago. Identifying this disorder and treating it in time can benefit the patient to a great extent. Though not a single treatment has turned successful in all patients. Some patients get relieved by behavioural therapy, while others respond to medical treatment.
强化阅读微技能训练，提升英语阅读能力——以新世纪英 语 8BU3L1 Hollywood 为例
Authors: 张 芳
Published: November 2019

英语语言学家约翰·芒比（John Munby）提出的微技能概念和《上海市中小学英语课程标准（征求意见稿）》均阐述了阅读技能的内涵与分类。为了进一步强化英语阅读微技能训练，提升初中生的英语阅读能力，本文根据英语阅读微技能的主要内涵与特点，结合实际教学案例，阐述目测技能、逻辑推测技能和理解技能在初中英语阅读教学中的有效渗透。
不同学习风格的学习者汉字书写质量自动测量与分析
Authors: 李 静 , 姜 杰 , 李 艺
Published: November 2019

借助智能书写评测系统和学习风格调查问卷，以中国江苏省南京市某小学三、四年级的学生为研究对象，探究低年级不同类型学习风格的学习者在汉字书写上的行为表现，得出以下结论：三、四年级的小学生大多是视觉型学习者，且易受书写材料（书写格、有无例字）的影响，非视觉型学习者所占比例比较少，不受书写材料的影响，其数据符合正态分布，在个别意义上有参考价值。并针对不同学习风格学习者的行为表现，提出合理化的建议。
“点阵技术”支撑下下的小学数学前置化建模教学实践探究——以人教版四年级下册《乘法分配律》一课为例
Authors: 李 文会
Published: November 2019

数学建模是指运用数学知识，从现实问题中抽象、提炼出数学模型，并用数学语言描述实际现象的过程。小学生形象化思维的特征决定了其数学建模过程应基于对大量的实际问题的感悟。本文以人教版四年级下册《乘法分配律》一课为例，浅谈数字化教学背景下“点阵技术”支持小学数学前置化建模教学的实践探究。
高校网络舆情传播规律及危机应对措施
Authors: 黎 玉洁
Published: November 2019

高校学生是网民主体，高校作为网络舆情的主阵地，极易滋生网络舆情，为网络舆情危机产生埋下隐患，因此必须注重高校网络舆情引导及危机应对研究。文章通过网络资料搜集和网络随机发放电子问卷方式进行调查并分析，总结高校网络舆情传播规律及存在的问题，并对此提出高校网络舆情管理体系构架和高校网络舆情危机应对措施。
综合性大学的拔尖创新人才培养模式
Authors: 胡 明宇
Published: November 2019

“创新驱动”是国家发展所需、世界大势所趋。人才是创新的核心要素，培养拔尖创新创业人才是时代对高校的重要使命。本文主要以武汉大学的教育改革措施为例，强调了拔尖创新人才培养的重要性，并针对拔尖创新人才培养模式探索中出现的问题，提出了综合性大学后续工作的重点，包括倡导人才培养是基础的价值导向，整合院系优势资源；加强创新创业课程体系的质量监督和课程成果考核，大力推进创新实践活动；提高创新人才培养的试点班的多元性，发扬个性化教育；为教师科研创新服务，并进行监督和指导。
Effects of medial and lateral wedged orthoses on knee and ankle joint loading in female runners
Authors: Sinclair Jonathan , Stainton Philip
Published: November 2019

The aim of the current investigation was to examine the effects of orthoses with a 5°
medial and lateral wedge on knee and ankle joint kinetics in female runners.
Twelve healthy female runners ran at 3.5 m/s over a force platform in three
conditions (medial, lateral and no-orthotic). Lower extremity kinematics were
measured using an 8-camera motion capture system, which allowed knee and ankle loading to be explored using a musculoskeletal modelling approach. The peak
Achilles tendon force was significantly larger in the no-orthotic condition
(5.34 BW) compared to the lateral orthosis (5.03 BW). The peak patellofemoral
stress was significantly larger in the medial orthosis (7.32 MPa) compared to
the no-orthotic (7.02 MPa) condition. Finally, the peak knee adduction moment
was significantly larger in the medial condition (1.14 Nm/kg) compared to the
lateral (0.99 Nm/kg) orthosis. The findings from the current investigation
indicate that lateral orthoses may be effective in attenuating risk of medial
tibiofemoral osteoarthritis and Achilles tendinopathy, but medial wedge
orthoses may increase the risk of patellofemoral pain in female runners.
Analisis Nilai Karakteristik Tokoh Utama pada Novel Haid Pertama Karya Enny M.
Authors: Tutu Muliati
Published: November 2019

AbstrakPenelitian ini bertujuan memperoleh pengetahuan tentang karakter tokoh utama dalam novel Haid Pertama karya Enny M. Penelitian ini adalah penelitian pustaka dan merupakan penelitian deskriptif kualitatif. Sumber datanya adalah novel Haid Pertama, merupakan hasil karangan atau imajinasi Enny M. yang berwujud menjadi kenyataan dalam bentuk karya yang utuh yaitu novel. Teknik yang digunakan adalah teknik observasi tidak langsung atau biasa dikenal dengan istilah observasi berstruktur.  Hasil analisis data yang dihimpun, peneliti menentukan faktor-faktor edisi atau deskripsi tokoh utama sesuai dengan bukti atau petunjuk yang ditentukan. Jadi dapat dikatakan bahwa gambaran karakter tokoh utama dalam novel Haid Pertama yaitu Diena, adalah gambaran karakter seorang tokoh yang masih gadis belia segolongan SMP yamg masih kekanak-kanakkan, selalu mencari hiburan dirinya, sedikit kasar, rajin berusaha dan suka berpenampilan menarik atau tampil beda di hadapan teman-temannya.Sifat kekasaran yang dimiliki Diena merupakan akibat kegelisahan dari keterlambatan datang haidnya, karena ia merasa cemas dan gelisah kalau nantinya Diena akan menjadi wanita yang tidak normal atau mandul, serta merasa malu terhadap teman-temannya dan orang lain. Namun sifat kekasaran Diena tidak menjadi sebuah karakter remaja yang bersifat kepribadiannya. Karena setelah berumur 14 tahun, tepat hari ulang tahunnya Diena mendapatkan hadiah ulang tahun dari yang Kuasa dengan sebuah kado yang istimewa yang selama ini Diena dambakan, yaitu haid pertamanya.Kata Kunci: Nilai, karakterisik, tokoh utama, novel Haid pertama
Kadar Lemak dan Air Pada Cookies dengan Substitusi Tepung Ubi Ungu dan Kacang Tanah
Authors: Izza Nadia Karomatul , Hamidah Nanik , Setyaningrum Yahmi Ira
Published: November 2019

Cookies are crispy textured cakes. The main ingredient used to make cookies is wheat flour. Substitution of flour with purple sweet potato is done because purple sweet potato has content such as wheat flour. Purple yam flour contains amylose of 24.79% and amylopectin of 49.78%.This research was conducted to analyze on fat level and water content in cookies. The study design was a Randomized Block Design. The treatment level was divided into 4 groups with the proportion of purple sweet potato flour:  F0 (0%: 0%), F1 (55%: 20%), F2 (45%: 30%), and F3(35%: 40 %). Fat content analysis used was the soxhlet method. There was a significant effect (ρ = 0,000) on the amount of fat content in cookies. The highest fat content found in F3 was 38.85%.Water content analysis used was the Thermogravimetric method. Statistical analysis of water content using friedmen with a reliability level of 95%. There was a significant effect (ρ = 0,000) on the amount of water content in cookies. The lowest water content was in F3 of 38.85%. The higher the addition of peanut flour, the lower the water content of cookies. Keywords: Cookies, Purple Sweet Potatoes, Ground Peanuts, Fat Levels, Water Content
El envejecimiento en América Latina y el Caribe: las dos posturas. Cómo estamos en Paraguay
Authors: Leguizamón María Angélica , Kochmann Sonnia
Published: November 2019

El proceso de envejecimiento se ha convertido en un reto conocido y una realidad que va adquiriendo mayor espacio, sobre todo en América Latina y el Caribe, por la transformación demográfica inédita y, tal vez, irreversible producida. El incremento de las personas mayores es una tendencia mundial que influye en la economía, la planificación del desarrollo, las políticas sociales, las familias, las comunidades locales y las grandes ciudades. En cuanto a sus implicaciones, es, probablemente, la transformación más importante en curso. Mientras, el Fondo Monetario Internacional considera que se subestimó la evolución demográfica de la población y que, el aumento de la longevidad puede crear un serio riesgo, al significar una amenaza para la sostenibilidad de las finanzas públicas en el futuro. Los problemas que afectan a la población adulta mayor en la actualidad, tendrán efectos en el resto de la sociedad, sobre todo en un panorama de escasez de recursos. Los organismos que se ocupan del tema, así como la sociedad civil organizada, consideran que sin las previsiones suficientes, cuando los asuntos ligados al envejecimiento se hagan visibles, es fundamental que las necesidades e intereses de este grupo social y sus soluciones, conduzcan a la construcción de una sociedad para todos.
El analfabetismo en Paraguay
Authors: Arias Carmen
Published: November 2019

El presente trabajo tiene por objetivo analizar la variable “¿Sabe leer y escribir?” captada en la Encuesta Permanente de Hogares (EPH) del año 2017 para cuantificar y caracterizar a la población analfabeta en el Paraguay. La investigación es del tipo descriptivo, donde se realiza el análisis a partir del cruce de la variable “¿Sabe leer y escribir?”, con indicadores de pobreza y variables demográficas. Los resultados obtenidos dan cuenta de que el indicador toma relevancia cuando se realiza la clasificación de la población de 15 años y más, ya que existe un amplio porcentaje de esta población a la que le resulta muy difícil insertarse al mercado laboral. Además, pone en evidencia que un 56,4% de esta población está representada por las mujeres y que el grupo de personas de 30 a 64 años en condiciones de analfabetismo en el área rural, duplica a sus pares del área urbana. Al analizar las variables considerando el estatus de pobreza, del grupo de población analfabeta de 15 años o más, el 57,6% son no pobres y alrededor de 201.400 personas tiene un ingreso laboral con promedios por debajo del sueldo mínimo vigente (2017).
Enfermedades mentales crónicas: características y frecuencia en el Hospital Regional del Este
Authors: Zandonai Andre
Published: November 2019

La salud mental en el Paraguay necesita soluciones innovadoras y urgentes, ya que las enfermedades mentales crónicas producen afectan marcadamente la vida de las personas que la padecen. Los objetivos de este trabajo fueron: determinar las características y la frecuencia de los Trastornos Mentales registrados en el Área de Psiquiatría del Hospital Regional de Ciudad del Este, en el quinquenio 2005-2010, hallar la incidencia y prevalencia de los Trastornos Mentales, así como también, analizar el tipo de servicio ofrecido a los pacientes del área citada. La investigación fue descriptiva, con un diseño no experimental. La metodología empleada fue el Análisis Documental Retrospectivo y el instrumento utilizado para la clasificación de los casos diagnosticados fue el Código Internacional de Enfermedades (CIE-10). La muestra fue integrada por 3.681 expedientes (71% del total de expedientes disponibles), de acuerdo a los criterios de inclusión establecidos. Los resultados indican que aproximadamente 1000 pacientes por año son registrados en el área de psiquiatría. La clasificación fue la siguiente: los trastornos esquizofrénicos ocupan el 41% del total de casos, los trastornos del humor el 32%, los trastornos somatomorfos el 17% y los trastornos mentales orgánicos el 6%, otros trastornos el 4%. Se concluye que los Trastornos Mentales registrados son considerados por la Organización Mundial de la Salud como “trastornos mentales severos y persistentes”.
SİBER GÜVENLİK POLİTİKASI: ABD, RUSYA VE ÇİN ÜZERİNE KARŞILAŞTIRMALI BİR ANALİZ
Authors: GÖÇOĞLU Volkan , AYDIN Mehmet Devrim
Published: November 2019

Ülke sınırlarının ulusal güvenlik politikası açısından taşıdığı önem,
son yıllarda giderek hızlanan küreselleşme süreci ile birlikte azalmaya
başlamıştır. Küreselleşme ile birlikte dünyada, ülkelerin güç dağılım kanalları
yeniden şekillenmiş, asimetrik güç ilişkileri ortaya çıkmış ve ulusal güvenlik
ihtiyaçları yeniden tanımlanmıştır. Son yıllarda yaşanan teknolojik gelişmeler
siber güvenlik kavramını ortaya çıkarmış ve siber güvenlik, ulusal güvenliğin
önemli bir unsuru haline gelmiştir. İnternetin, ülkelerin sınırlarını aşan
yapısı, internet ağlarının bireysel hizmetlerin ve amaçların ötesinde devletin
kritik altyapılarında ve kamu hizmetlerinin yürütülmesinde kullanılması, gün
geçtikçe gelişen e-devlet uygulamaları, siber güvenliğin ulusal güvenlik
içerisindeki önemini daha da pekiştirmiştir.  
Bu bağlamda, çalışmada ABD, Rusya ve Çin’in siber güvenlik politikaları,
özellikle bu üç ülkede yayınlanan resmi politika belgeleri temelinde
incelenmekte ve karşılaştırmalı bir analiz yapılmaktadır.
GÜVENLİK GÜÇLERİNİN BİLGİ GÜVENLİĞİ FARKINDALIĞINI BELİRLEMEYE YÖNELİK BİR ARAŞTIRMA
Authors: TANER Emre , KILIÇ İbrahim
Published: November 2019

Bu araştırmanın amacı,
emniyet ve asayiş ile kamu düzenini korumakla görevli olan emniyet personelinin
bilgi güvenliği farkındalık düzeylerinin tespit edilmesidir. Çalışmaya,
Siirt'te görev yapan 207 jandarma ve 197 polis olmak üzere toplam 404 personel katılmıştır.
Veri toplama aracı olarak anket kullanılmıştır. Verilerin analizinde, betimsel
istatistiklerin (frekans, yüzde, ortalama, standart sapma) yanı sıra, bilgi
güvenliği farkındalık düzeylerinin katılımcıların demografik özelliklerine göre
karşılaştırılmasında t testi ve varyans analizi kullanılmıştır. Araştırma
sonucunda, bilgi güvenliği farkındalık düzeyi ölçeğinin "saldırı ve
tehditler" alt boyutuna ilişkin genel ortalama 2,32 ve "kişisel
verileri koruma" alt boyutuna ilişkin genel ortalama ise 2,87 olarak
hesaplanmıştır. Bu değerler emniyet personelinin bilgi güvenliği farkındalık
düzeylerinin yüksek olmadığını hatta ortalamanın altında olduğunu
göstermektedir. Diğer taraftan katılımcıların bilgi güvenliği farkındalık
düzeylerinin bazı demografik özellik değişkenlerine göre farklılık gösterdiği
tespit edilmiştir. Araştırma sonuçları, emniyet personelinin bilgi güvenliği
farkındalık düzeylerinin artırılmasına yönelik önlem alınmasını ve gerekli
çalışmalar yapılmasını ortaya koymuştur. Bununla birlikte konu ile ilgili
farklı çalışmaların farklı illerde farklı örneklemlerle yapılması bilgi
güvenliği farkındalık düzeyinin mevcut durumunu betimleyecek, literatüre önemli
katkılar ve ilgili birimlerin önlem alması konusunda yöneticilere önemli veri
kaynağı oluşturacaktır.
Population Structures of the Two Banded Seabream, Diplodus vulgaris and the White Seabream, Diplodus sargus Reveal New Records in Maximal Age
Authors: DARMANİN Sandra Agius , KARAKULAK F. Saadet , VELLA Adriana
Published: November 2019

The common two-banded seabream Diplodus vulgaris and Diplodus sargus were sampled from

non-commercial fishing catches around the Maltese Islands between July 2012 and December

2017. A total of 1550 (D. vulgaris N=1204, D. sargus N=346) specimens were collected. In this

study, age, growth, length-weight relationship (LWR), condition factor (K) and relative condition

factor (Kn) were investigated. Ages ranged from 0 to 17 years for D. sargus and 0 to 16 years for

D. vulgaris. A positive allometric growth was observed for D. sargus while growth in D. vulgaris

was isometric. Average Kn was found to be 0.99 and 1.01 in D. vulgaris and 0.97 and 1.00 in D.

sargus for males and females respectively. The growth parameters of the von Bertalanffy equation

were: L∞=26.71 and 30.86 cm, K= 0.275 and 0.286 year-1

and tₒ = -2.27 and -1.61 year for all

individuals of D. vulgaris and D. sargus respectively. This study is the first reference on the LWR

equation parameters, Kn, K and Age for these species around the Maltese Islands and establishes

a new maximum age for D. vulgaris of 16 years.
Immunostimulatory and Immunomodulatory Effects of Nitzschia navis-varingica, Heterocapsa pygmaea and Chrysochromulina alifera Whole Cell Extracts on Mammalian Macrophage Cells
Authors: AYAZ Furkan
Published: November 2019

Microalgal species have been used as a food source and as medicine since ancient times in Africa, Mexico and China. In our study we focused on the whole cell extracts of three microalgal species that have not been studied before: the diatom Nitzschia navis-varingica, the haptophyte Chrysochromulina alifera and the dinoflagellate Heterocapsa pygmaea. Effects of the diatom Nitzschia navis-varingica, the haptophyte Chrysochromulina alifera and the dinoflagellate Heterocapsa pygmaea on mammalian macrophage cells were investigated first time in this study. A significant anti-inflammatory impact of cell extracts in distilled water was observed. Direct anti-inflammatory influence of the extracts without any solvents or further processes facilitates its usage in biotechnology. Furthermore, the ability to include these species in the human diet brings out new opportunities in terms of increasing the tolerance to certain allergic food products in patients with allergic reactions as well as inflammatory bowel disease. Moreover, these species can be used in the creams for the atopic applications on the skin to prevent skin allergies. With this study we are presenting data supporting the biotechnological potential of the diatom Nitzschia navis-varingica, the haptophyte Chrysochromulina alifera and the dinoflagellate Heterocapsa pygmaea species against inflammatory and allergic reactions.