bluuebunny/crossref_metadata_2025 huggingface dataset:
Executioner caspases degrade essential mediators of pathogen-host interactions to inhibit growth of intracellular Listeria monocytogenes
Authors: Lavergne Marilyne , Schaerer Raffael , De Grandis Sara , Bouheraoua Safaa , Adenuga Oluwadamilola , Muralt Tanja , Schaerer Tiffany , Chèvre Léa , Failla Alessandro , Matthey Patricia , Stumpe Michael , Kressler Dieter , Mantel Pierre-Yves , Walch Michael
Published: January 2025

Cell death mediated by executioner caspases is essential during organ development and for organismal homeostasis. The mechanistic role of activated executioner caspases in antibacterial defense during infections with intracellular bacteria, such as Listeria monocytogenes, remains elusive. Cell death upon intracellular bacterial infections is considered altruistic to deprive the pathogens of their protective niche. To establish infections in a human host, Listeria monocytogenes deploy virulence mediators, including membranolytic listeriolysin O (LLO) and the invasion associated protein p60 (Iap), allowing phagosomal escape, intracellular replication and cell-to-cell spread. Here, by means of chemical and genetical modifications, we show that the executioner caspases-3 and -7 efficiently inhibit growth of intracellular Listeria monocytogenes in host cells. Comprehensive proteomics revealed multiple caspase-3 substrates in the Listeria secretome, including LLO, Iap and various other proteins crucially involved in pathogen-host interactions. Listeria secreting caspase-uncleavable LLO or Iap gained significant growth advantage in epithelial cells. With that, we uncovered an underappreciated defense barrier and a non-canonical role of executioner caspases to degrade virulence mediators, thus impairing intracellular Listeria growth.
Re-architecture for requirements of academic space development in the universities: design and validitation of RASD questionnaire
Authors: Karimian Zahra , Abolghasemi Mahmoud
Published: January 2025

Universities are the cornerstone of social development and progress; however, it is essential to enhance the academic environment to support this mission. The objective of this research is to identify the Requirements for Academic Space Development (RASD) in universities. The present study was conducted in 2022–2023 using a mixed-method with a qualitative-quantitative sequence. The qualitative section was conducted using purposive sampling and semi-structured interviews with 20 experts of Iranian universities. The data were analyzed using content and thematic analysis at three levels of codes (Items), components, and themes (Main concepts), and then, it was examined quantitatively using a survey on 265 faculty members. For data analysis and validate the instrument, the face and content validity (CVI/CVR), reliability and construct validity were examined. Exploratory and confirmatory factor analysis were used to validate the questionnaire using SPSS 24 and Liseral 8.5 software. In qualitative stage, 67 codes, 4 concepts (formal, political, cultural, and scientific), and 14 components were extracted, which resulted in the word “Re-architecture” based on the acronym of the first letter. The content validity of the RASD questionnaire was confirmed with CVI = 0.941 and CVR = 0.940. The overall reliability was 0.962. For construct validity, first, the sample adequacy was confirmed with KMO = 0.928 and the Bartlett test (P < 0.001). In general, the quantitative section also extracted 14 factors that estimated 70.229% of the total variance. The “Happiness” had the highest factor loading (30.35%), followed by “Unity” (6.11%), “Thinking” (4.23%), Refining” (3.87%), “Expediency” (3.22%), and “Interaction” (2.83%) with the highest factor loadings. Universities need a rethinking, a concept that has been addressed in this research as “Re-architecture”. Perhaps the choice of this term is appropriate because we also need changes in universities, by combining science, re-engineering, cultural considerations, and an artistic integration of all factors influencing academic development.
Statistical-based detection of pilot contamination attack for NOMA in 5G networks
Authors: Nashat Dalia , Khairy Sahar
Published: January 2025

Fifth-generation (5G) communication technologies, such as millimeter wave communication, massive multiple-input-multiple-output and non-orthogonal-multiple-access (NOMA) are playing a pivotal role in promoting the modern applications of the Internet-of-Things. Using non-orthogonal resource allocation, NOMA can increase spectrum efficiency and achieve wide connectivity with low transmission delay and signaling cost. Despite the high potential of NOMA in 5G communications, NOMA is susceptible to a pilot contamination attack (PCA), in which an attacker resents the same pilot signals as authorized users. Currently, using the available detection methods in NOMA gives high false positive probability since the time-division-duplex or orthogonal resource block can be allocated by many authorized user. Since the pilot contamination attack changes the signal reception at the legitimate receiver, this work introduces a novel detection scheme for identifying Pilot Contamination attack (PCA) that statistically investigates the asymmetry in received signal power levels. The main idea of the proposed detection scheme is to use various statistical measurements for normal traffic attributes (CSI) as a reference profile. Then, compute the Mahalanobis distance between the reference profile and CSI for the incoming connection and use the probability of the uniform distribution to make the final detection decision. The performance of the proposed detection technique in terms of its detection rate and false positive probabilities has been evaluated through extensive simulation. The simulation results show that the proposed scheme succeeded in detecting the pilot contamination attack with a detection rate of up to 98% and a precision reached 97.88%.
scRNA seq of an F1 cross of Marek’s disease resistant and susceptible chickens identifies allele specific expression signatures enriched in transcription modulators
Authors: Velez-Irizarry Deborah , Cheng Hans , Hearn Cari
Published: January 2025

Marek’s disease (MD), a T cell lymphoma disease in chickens, is caused by the Marek’s disease virus (MDV) found ubiquitously in the poultry industry. Genetically resistant Line 63 (L6) and susceptible Line 72 (L7) chickens have been instrumental to research on avian immune system response to MDV infection. In this study we characterized molecular signatures unique to splenic immune cell types across different genetic backgrounds 6 days after infection. Using three populations, L6, L7, and an F1 cross between L6xL7, we evaluated the immune cell transcriptome of responding cell types using single cell RNA sequencing. Several MDV genes were found expressed mainly in cytotoxic T cells while ICP4 and MEQ MDV genes were expressed across infected cell types. Using the F1 we quantified allele specific expression (ASE) of biallelic SNPs and found biased expression of parental alleles specific to immune cell subtypes. We identified 22 SNPs with ASE in response to MDV infection mapped to gene rich regions surrounding 59 genes of critical importance for chromatin remodeling and transcriptional regulation. Histone deacetylase genes (HDAC1 and HDAC8) had increased expression of L6 alleles, while small nuclear RNA genes (SNORA68 and SNORA72) expressed higher levels of L7 alleles with infection in T cell subsets. SNPs with ASE also mapped genes important for an adequate immune response including GNLY (cytotoxic activity) and PDIA3 (component of MHC class I peptide loading complex), and genes known to promote viral replication (MCM5 and EIF3M). These results show that functional variants associated with susceptibility to MD may have a bigger impact in subsets of immune cell types, and by characterizing the transcriptomes of these subtypes we can unravel molecular signatures specific to MD genomic resistance.
A wash-free AIE fluorescent probe for monitoring lipid droplets and identifying tumors
Authors: Zhang Xue , Wang Jie , Zhang Sichen , Li Jiale , Sun Aobo , Wei Tianjian , Wang Chunfei , Hu Lei , Zhou Lutan , Wang Hui
Published: January 2025

The abnormal size and number of lipid droplets (LDs) are closely associated with a variety of diseases, including metabolic syndrome related diseases, liver disease and tumors.
Iodine-mediated regioselective C-3 sulfenylation using elemental sulfur and arylhydrazine hydrochloride to access 3-sulfenylated imidazo[1,2-a]pyridines
Authors: Kishor Kaushal , Prabhakar Neha Sharma , Singh Krishna Nand
Published: January 2025

A regioselective C-3 sulfenylation of imidazo[1,2-a]pyridines has been accomplished using arylhydrazine hydrochloride and elemental sulfur, in the presence of molecular iodine and DABCO via a transition metal-free protocol.
Correction: Towards the synthesis of polythiazolines: a post-polymerization approach
Authors: Mathianaki Aikaterini , Demeler Aysha Kinjo , Dömling Adrian , Ferrari Federico , Scheelje Frieda Clara M. , Bahmann Hilke , Delaittre Guillaume
Published: January 2025

Correction for ‘Towards the synthesis of polythiazolines: a post-polymerization approach’ by Aikaterini Mathianaki et al., Polym. Chem., 2025, https://doi.org/10.1039/d4py00930d.
Stereoselective construction of chiral flavanones via enzymatic intramolecular C(sp3)–H activation
Authors: Gao Hanzi , Africano Camargo Edgar , Ubi Jude N. , Duan Xiuyuan , Zheng Guojun , Gao Shuaihua , Yuan Qipeng
Published: January 2025

Structural dynamics-driven protein engineering was utilized to rationally evolve myoglobin, enhancing its intramolecular C(sp3)–H activation for diazo cyclization reactions.
Rapid synthesis of manganese dioxide nanoparticles for enhanced biocompatibility and theranostic applications
Authors: Wang Xueting , Yang Xiaoqing , Yi Xiaoqing , Min Xuehong , Jia Yongmei
Published: January 2025

Rapid preparation of MnO2 and by using MnO2 for colorimetric detection of GSH.
A free-radical initiator-based carrier-free smart nanobomb for targeted synergistic therapy of hypoxic breast cancer
Authors: Hu Liefeng , Dong Ganlin , Li Xiaohong , Li Shuting , Lv Yonggang
Published: January 2025

Tumor hypoxia still severely limits the antitumor efficiency. Herein, a free-radical initiator-based carrier-free smart nanobomb with oxygen-independent trimodal therapeutic effects for targeted therapy of hypoxic breast tumor at low dose.
Separator membranes for aqueous zinc–manganese oxide batteries: a comprehensive review on experimental results and theoretical simulations
Authors: Rodrigues-Marinho T. , Miranda D. , Barbosa J. C. , Gonçalves R. , Lanceros-Méndez S. , Costa C. M.
Published: January 2025

This work provides a review on theoretical simulation and experimental results in separator membranes for zinc–manganese oxide batteries, where this battery system has gained interest as an alternative to lithium-ion batteries.
Bias-free solar to ammonia photoelectrochemical conversion using a perovskite-silicon tandem absorber and 1T-MoS2 integration
Authors: Liu Tsung-Hsin , Huang Yu-Hsiang , Huang Yu-Xuan , Lu Yang-Sheng , Tsai Tsung-Min , Chang Chen , Kuo Pai-Chia , Shiue Jessie , Huang Yu-Ching , Chen Chun-Wei , Chen Chia-Chun , Li Shao-Sian
Published: January 2025

An artificial photosynthesis device for N2 to NH3 conversion realized using a Si-perovskite tandem absorber with a 1T-MoS2 catalyst.
Photoresponsive circularly polarized long-lived fluorescence in chiral liquid crystals via tunable stepwise energy transfer
Authors: Wang Xincan , Wang Jiani , Huang Sha , Yuan Yongjie , Zhang Hailiang
Published: January 2025

This research work provides a feasible strategy for preparing long-lived circularly polarized luminescent materials with excellent photocontrolled CPL properties.
Correction: The Sc2WxMo3−xO12 series as electrodes in alkali-ion batteries
Authors: Liu Junnan , Johannessen Bernt , Brand Helen E. A. , Andersen Henrik L. , Sharma Neeraj
Published: January 2025

Correction for ‘The Sc2WxMo3−xO12 series as electrodes in alkali-ion batteries' by Junnan Liu et al., CrystEngComm, 2021, 23, 3880–3891, https://doi.org/10.1039/D1CE00318F.
Insight into the roles of lactylation in macrophages: functions and clinical implications
Authors: Shu Min , Lu Dingci , Zhu Ziyi , Yang Fei , Ma Zhaowu
Published: January 2025

Lactylation, a post-translational modification, has been linked to gene transcription regulation through epigenetic modulation in various pathophysiological processes. The lactylation regulatory proteins, known as writers, erasers, and readers, govern their dynamics by adding, removing, and recognizing lactyl groups on proteins. Macrophages, as cells of the immune system, maintain homeostasis, responding dynamically to diverse internal and external stimuli. Emerging researches unveil that lactylation, through inducing macrophage activation and polarization, affects their functionality in pathological conditions such as inflammation, tumor microenvironment, and fibrosis. Evidence progressively indicates that lactate-driven alterations in lactylation levels within macrophages can influence the pathogenesis of numerous diseases. This review aims to systematically summarize the research progress of lactylation in macrophages, explore its functions and mechanisms by which lactylation contributes to the pathology of different disease phenotypes, and propose future research directions along with potential diagnostic and therapeutic strategies.
Measuring Intentional Communication in Infants at Elevated Likelihood of Autism: Validity, Reliability, and Responsiveness of a Novel Coding Scale
Authors: Choi-Tucci Elizabeth , Sideris John , Holland Cristin , Baranek Grace T. , Watson Linda R.
Published: January 2025

Purpose:

Intentional communication acts, or purposefully directed vocalizations and gestures, are particularly difficult for infants at elevated likelihood for eventual diagnosis of autism. The ability to measure and track intentional communication in infancy thus has the potential to aid early identification and intervention efforts. This study assesses the validity of a novel measure of intentional communication intended for use within semistructured caregiver–infant interactions.

Method:

The Intentional Communication Coding Scale (IC Coding Scale) captures infants' Vocalizations, Gestures, and Combined (vocalizations paired with gestures) acts. Using data from 36 infants at elevated likelihood for autism, we tested the convergent and discriminant validity of the IC Coding Scale with established language measures using Spearman's rho. We tested interrater reliability using intraclass correlation coefficient (ICC) calculations. Finally, we tested responsiveness (i.e., sensitivity to change) using Wilcoxon signed-ranks tests and Spearman's rho.

Results:

Our initial psychometric tests suggested adequate levels of convergent and discriminant validity. ICCs ranged from .77 to .92, while confidence intervals were wide, suggesting that Gestures and Combined acts were coded more variably than Vocalizations were among raters. Tests of the scale's responsiveness suggested adequate sensitivity to change across a 12-week period.

Conclusions:

This study is an important first step toward validating the IC Coding Scale for use in measuring and tracking intentional communication behaviors in infants at elevated likelihood for autism within more naturalistic, semistructured activities. Additional studies are needed to disentangle the effects of intervention from maturation and to examine types of intentional communication acts in more detail.
Working Memory Deficits in School-Age Children With Cochlear Implants Are Primarily Explained by Deficits in the Processing of Auditory and Lexical Information
Authors: Pesnot Lerousseau Jacques , Denis Maude , Roman Stéphane , Schön Daniele
Published: January 2025

Purpose:

Prelingual deaf children with cochlear implants show lower digit span test scores compared to normal-hearing peers, suggesting a working memory impairment. To pinpoint more precisely the subprocesses responsible for this impairment, we designed a sequence reproduction task with varying length (two to six stimuli), modality (auditory or visual), and compressibility (sequences with more or less regular patterns). Results on 22 school-age children with cochlear implants and 21 normal-hearing children revealed a deficit of children with cochlear implants only in the auditory modality. We observed no deficit in the visual modality and no deficit in the ability to detect and use regular patterns to improve memorization.

Conclusion:

These results suggest that the working memory deficit of children with cochlear implants is explained by an impairment in the processing, encoding, and/or storage of the auditory and lexical information, as opposed to a global storage deficit or an inability to use compressibility strategies to improve memorization.

Supplemental Material:

https://doi.org/10.23641/asha.28216088
Development of an autonomous Internet of Things system for distributed production of boxed flat sheet metal parts in railcar manufacturing
Authors: Matenga Alice Elizabeth , Mpofu Khumbulani
Published: January 2025

Railcar manufacturing takes place in a multi‐tier production environment, where scheduling and resource allocation are two of many critical components of operations management. In general, organizations harness the opportunities presented by enterprise information systems (EIS) with connected devices to enhance the efficiency of their supply chains. However, systematic vulnerabilities emerge in these EIS due to a lack of unified and synchronized data management systems across enterprises. Industry 4.0 (i4.0) prompted the adoption of cyber‐physical systems (CPS) in industry, creating new opportunities to address these vulnerabilities. A key challenge identified in planning and developing autonomous Internet of Things (IoT) system lies in integrating and managing data from multiple sources, which come in various formats, and is generated in different scales, using different platforms. Hence, the study centred on developing a cloud‐native autonomous manufacturing application, with bi‐directional data flow for production of boxed flat sheet metal parts in a distributed network of manufacturing suppliers. Serverless computing enables integration of information technology and operational technology (IT/OT) for real‐time control and monitoring of industrial Internet of Things operations (IIoT). An autonomous manufacturing system is developed for the closed‐loop manufacturing supply chain (SC), utilizing a system‐to‐system (SoS) approach.
Prebiotic ability of musa balbisiana colla stems on the growth of Pediococcus acidilactici in vitro and probiotic encapsulation
Authors: Singapurwa Ni Made Ayu Suardani , Candra I Putu , Semariyani A.A. Made , Nursini Ni Wayan , Kusumaningsih Purwaningtyas , Jiwantara Gusti Ngurah Oka , Djelantik Sang Ayu Made Agung Prasetiawati
Published: January 2025

Musa balbisiana Colla banana is a plant that has many benefits, one of which is useful as a traditional medicine using its stems. Banana stems have potential as a source of prebiotics because they contain carbohydrates and oligosaccharides which can support the growth of good bacteria in the digestive tract. Probiotic encapsulation was carried out to determine the role of Musa paradisiaca stems as a prebiotic in digestion. The encapsulation process is carried out using chitosan, carrageenan, and maltodextrin. The results showed that the prebiotic banana stem Musa paradisiaca could increase the growth of Lactobacillus sp. significantly at certain concentrations, with the most optimal results at a concentration of 6.89% compared to the control. Based on test results, Musa paradisiaca stem flour contains a fructan percentage of 0.14 ± 0.001%. The presence of fructan compounds makes Musa paradisiaca stem flour function as an effective source of natural prebiotics. The test results showed that the biocapsulation contained 2.7 x 103 cfu/gram of lactic acid bacteria. This shows that the bioencapsulation process of lactic acid bacteria was successful. Encapsulation can protect probiotics from extreme conditions during processing and storage, as well as from acidic pH in the digestive tract.
Communicating climate change: The role of nature-based community development program in enhancing stakeholders engagement
Authors: Widhagdha Miftah Faridl , Muktiyo Widodo , Kartono Drajat Tri , Padmaningrum Dwiningtyas
Published: January 2025

Climate change is a global problem that affects not only the elite but also local communities. Climate change has an impact on both urban and rural inhabitants, with droughts and crop failures among the most severe. In Indonesia, specifically in the village of Sungai Pakning, Bengkalis Regency, Riau Province; the Plaju sub-district, Palembang City, South Sumatra Province; and Klayas village, Sorong Regency, Southwest Papua Province. Climate change poses concern such as peatland fires, coastal erosion, rising temperatures, and limited availability to clean water and local food. This study is a case study undertaken in three places, concentrating on climate change communication initiatives carried out through the use of nature-based community development program. Climate change communication is carried out through the empowerment program by adopting a participatory approach, using local evidence as the primary information basis, involving local actors or local figures, conducting capacity-building training, and forming local community networks, all of which are executed through the implementation of nature-based community development program. The result is that by effectively implementing climate crisis communication, community empowerment programs can strengthen stakeholder engagement.
Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes
Authors: Irwan Irwan , Pohan Napitupulu Nurhasanah , Amri MC Ulil , Adawiyah Rabiyatul , Akram Habibul , Nursafiah Nursafiah , Nurliza Eli
Published: January 2025

Propionibacterium acnes is the main organism that leads to acne. P. acnes belongs to a group of gram-positive bacteria. Antibiotics can be used to relieve acne, but they could lead bacteria to accumulate resistance. As a result, a safe and cost-effective treatment strategy is required. An instance is using Acrostichum aureum Linn leaves, which contain several bioactive chemicals that function as antibacterial. This study aims to identify the bioactive compounds and antibacterial activity of the methanolic extract of Acrostichum aureum Linn against Propionibacterium acnes. The study started with extraction (maceration method) with methanol solvent for 3 days, followed by phytochemical tests to identify bioactive compounds, and an antibacterial activity test using the disc diffusion method. Phytochemical tests on the methanol extract of Acrostichum aureum Linn leaves revealed five bioactive compounds consisted of alkaloids, flavonoids, tannins, steroids, and saponins. Antibacterial tests against Propionibacterium acnes exhibited no inhibition zone at concentrations of extract from 5% to 75%. However, at 100% concentration, indicating strong inhibition of P. acnes growth (diameter zone is 16 mm). Based on the research, it is conceivable to conclude that the extract has strong antibacterial activity against Propionibacterium acnes at a concentration of 100%.
The effect of tidal currents on the hydrodynamics of tidal turbine systems
Authors: Firmadany Bayu , Ikhwan Muhammad , Saputra T. Murdani , Muttaqin Mohd Iqbal , Kazrina Cut Shilvani Maghfirahtil
Published: January 2025

The ocean is a highly potential source of renewable energy with various forms, including wave and tidal energy. Due to its vast composition, the ocean stores and transfers significant amounts of energy. This study focuses on analyzing tidal dynamics that affect the stability of tidal turbines. The method used involves developing a model between the hydrodynamics of the turbine blades and the protection of the generator, assuming that the blades have an optimal angle to harness various tidal current speeds. The generator is then examined through d-q diagram performance. The results indicate that the model’s stability depends on the initial d-q current strength without external current influence. Disturbances in the hydrodynamics of the turbine blades were found to affect the generator’s stability. The generator's voltage limit and the tolerance limit for tidal current strength have been determined to be at stationary conditions.
Seagrass communities on the North Coast of Aceh
Authors: Khairunnisa Khairunnisa , Zuhilma Dewi Arie , Ramadhani Pitri , Farahisah Harum
Published: January 2025

Seagrass density and biomass are key indicators of the health and productivity of seagrass ecosystems. This study aims to address the seagrass communities on the North Coast of Aceh. Seagrass data collection was conducted using the Seagrass Net parallel transect plot method. The data analyzed include density, biomass, and carbon estimates. Three species of seagrass have been identified in the northern waters of Aceh, include
Halodule pinifolia Halophila ovalis, and Halophila minor. Seagrass density ranged between 301 - 440 ind/m2. the dry biomass measurements across various seagrass species and research stations indicate that the belowground biomassa generally exceeds the above ground biomass. The carbon stock at the research site ranged from 58.85 to 69.82 g C/m². By focusing on species diversity, density, biomass, and estimation of carbon storage capacity, this research will provide valuable insights into the ecological and carbon storage functions of seagrass ecosystems in this region, contributing to their conservation and sustainable management.
Analysis of coral reef health based on the abundance of herbivorous reef fish in the waters of Krueng Raya, Aceh Besar
Authors: Ulfah Maria , Cindy Safitri Arsa , Andianto Dika , Zahra Avifah , Miswari Nur
Published: January 2025

The health and sustainability of coral reefs are influenced by the complex interactions of various organisms, and one indicator of their health is the presence of herbivorous reef fish. This study aims to analyze the health of coral reefs based on the abundance of herbivorous reef fish in the waters of Krueng Raya, Aceh Besar. The research was conducted in October 2023 at three stations. Data collection was carried out using the Point Intercept Transect (PIT) method for coral monitoring, while the herbivorous fish were assessed using the Underwater Visual Census (UVC) Belt Transect method. The results showed that the abundance of herbivorous reef fish ranged from 1597.92 ind/ha to 5918.18 ind/ha, with a total of families, 12 genera, and 25 species of herbivorous reef fish identified. The percentage of algae cover ranged from 4.65% to 35.55%. This study indicates an inverse relationship between the abundance of herbivorous reef fish and algae cover. As the abundance of herbivorous reef fish increases, the percentage of algae cover decreases.
Spatial assessment of soil erosion using the revised universal soil loss equation (RUSLE) model for sustainable marine ecosystems in the coastal of northern part, Aceh Province
Authors: Nanda Muhammad , Alwan Muhammad , Ghufran Muhammad , Fahlefy M. Iqbal Ichsan , Husein Ismail , Haridhi Haekal Azief , Munir Badrul , Sari Intan Mulia , Asyqari Amir , Hasyem Tarmizi , Muhammad Muhammad , Permatasari Indah , Yunus Sayed
Published: January 2025

Coastal erosion presents a significant danger to sustainable marine ecosystems, especially in the northern coastal area of Aceh Province, Indonesia. This research combines the Revised Universal Soil Loss Equation (RUSLE) model with GIS and remote sensing to provide an innovative spatial evaluation of soil erosion risks. This study produces high-resolution maps of erosion risk and sediment yield by integrating precipitation patterns, soil properties, topography, and land use data. The results indicate substantial areas of soil erosion that contribute to sediment accumulation in coastal regions, which may affect marine ecosystems and increase land-sea connectivity issues. This methodology enhances the utilization of RUSLE in coastal environments and offers practical guidance for erosion mitigation and sustainable land management. The study highlights the significance of mitigating soil erosion as an important factor in attaining SDG 14 (Life Below Water), emphasizing the necessity for integrated policies to reduce land degradation and its subsequent effects on marine ecosystems. The findings highlight the significance of geospatial tools to encourage evidence- based decision-making for sustainable management of coastal and marine resources.
Recent	advances	in	carbon-based	adsorbent materials for ammonium removal from water
Authors: Ali Akbar Said , Mauliza Lisa , Rizki Fazli Rahmad
Published: January 2025

This systematic review examines recent advancements in carbon-based adsorbent materials for ammonium removal from water, a critical issue due to contamination from agricultural, domestic, and industrial sources. Elevated ammonium levels disrupt aquatic ecosystems and compromise water quality. Among various technologies, ion exchange and adsorption using materials such as activated carbon (AC) and biochar are highlighted for their efficiency, cost-effectiveness, and environmental benefits. Modified adsorbents, like manganese oxide-loaded AC, significantly enhance removal performance. Biochars, particularly those modified with NaOH and Mg2+, show improved capacities, especially when combined with heterotrophic nitrifying bacteria (HNB). Carbon nanotubes (CNTs), especially multi-walled CNTs, demonstrate superior adsorption capabilities. Direct contact membrane distillation (DCMD) with CNT- immobilized membranes also shows promise. Lignite, a low-rank coal, proves to be an economical natural adsorbent with enhanced performance through aerobic dewatering and oxidation. Future research should optimize these materials for real-world applications, pilot-scale studies, and complex wastewater matrices.
Inhibitory effect of chitosan and gelatin on the physical, chemical, organoleptic and mikrobiological quality of keumamah fish
Authors: Khafiyya Nida , Uju  , Bustami
Published: January 2025

Keumamah is a traditional fish product made from boiled and sun-dried skipjack, tuna, or mackerel. Keumamah has problems with quality decline and short shelf life. Chitosan, known for its antimicrobial properties, and gelatin, recognized for its ability to form protective layers and preserve food color, are promising natural preservatives for fish products. This study aims to evaluate the effects of chitosan and gelatin on the physical, chemical, organoleptic, and microbiological qualities of keumamah fish. The research utilizes a factorial complete randomized design (CRD) with three treatments: 1% chitosan, 3% gelatin, and a combination of 1% chitosan and 3% gelatin, assessed over storage periods of 0, 7, and 14 days. Key parameters measured include proximate composition, pH, texture, color, peroxide value, water activity (aw), total volatile base (TVB), and total plate count (TPC). The findings indicate that chitosan treatment resulted in the lowest TVB value of 43.57 mg/100g and the lowest peroxide value of 5.11 meq/kg, significantly enhancing the preservation of keumamah. Based on organoleptic tests, gelatin treatment effectively maintained the best texture, while chitosan demonstrated superior preservation of color and aroma due to its antimicrobial properties.
Checklist of commercially important Scombridae in Aceh, Indonesia
Authors: Azzahra Rudi Reefa , Tria Aswina Cut , Ulfa Khaira Nanda , Muhammad Razi Nanda , Muchlisin Zainal A. , Ramadhaniaty Mutia , Riska Rahayu Sri , Damora Adrian , Siti-Azizah Mohd Nor , Fadli Nur
Published: January 2025

The Scombridae family represents one of the most commercially valuable groups of pelagic fish, widely consumed across the globe. Despite their economic importance and high market demand, scientific data on Scombridae species in Aceh remains scarce. This study aimed to document Scombridae landings from Aceh waters. Fish samples belonging to the Scombridae family were collected from several Fish Landing Sites (TPIs) across Aceh Province. The collected samples were subsequently analyzed at the Genetics and Aquatic Biodiversity Laboratory, Faculty of Marine and Fisheries, Universitas Syiah Kuala. A total of ten Scombridae species were identified from the collected samples: Auxis rochei, Auxis thazard, Euthynnus affinis, Katsuwonus pelamis, Rastrelliger brachysoma, Rastrelliger kanagurta, Scomberomorus commerson, Scomberomorus guttatus, Sarda orientalis, and Thunnus albacares. Banda Aceh had the highest distribution of fish of the Scombridae family, followed by Meulaboh. The findings of this study provide critical baseline data for the future management and conservation of Scombridae fish, particularly in Aceh and Indonesia more broadly.
Biodiversity of important commercial fish in Lhok Bengkuang fish landing, Tapaktuan regency, southern part of Aceh, Indonesia
Authors: Haris Iqbal Teuku , Putri Nazira
Published: January 2025

This study was conducted at the Lhok Bengkuang fish landing in Tapaktuan regency, located in the southern part of Aceh Province, Indonesia, throughout May 2024. Fish samples were collected daily from wild catches using a bottom gill net with a 2.5-inch mesh size. The collected fish were sorted, identified, and recorded for the total number of each species. Over the study period, a total of 2,880 fish specimens from 24 different species were recorded. Notably, 80.66% of the total catch was dominated by three species: Eubleekeria splendens (56.94%), Selaroides leptolepis (12.78%), and Gerres oyena (10.94%). The least abundant species included Loligo vulgaris (0.14%), Carcharhinus amblyrhynchoides (0.10%), and Arius thalassinus (0.07%). The conservation status of these species revealed that 19 species (79.18%) were classified as Least Concern (LC), 2 species (8.33%) as Near Threatened (NT), 2 species (8.33%) as Vulnerable (VU), and 1 species (4.16%) as Data Deficient (DD). The study highlights the impact of environmental factors, seasonal fish migrations, and nutrient availability on fish diversity. These findings provide valuable insights into the composition and community structure of fish species in Lhok Bengkuang coastal waters.
Effect of hook size on the catch of hand line fishing at PPI Lambada, Aceh Besar
Authors: Julia Mizulni Putri , Rizki Purnama Nanda , Fauzan Lubis Ahmad , Salma Bunuatus , Twentina Dolorosa Butar-Butar Maretty
Published: January 2025

Generally, fishermen in Lambada Lhok Village conduct fishing activities using hand line fishing gear. This study aims to determine the difference in the size of the fishing line on the catch and to determine the level of effectiveness. The research was conducted in June 2024 at Fish Landing Base (PPI) Lambada. The method used was experimental fishing, namely by conducting fishing operations directly using hooks with sizes 15, 16, and 17 mm. Data collection was carried out based on the catch of hand line landed at Lambada Fish Landing Base (PPI). The results showed that the difference in the size of the fishing line had a significant effect on the catch. Based on the results, it was determined that the 15 mm hook achieve the highest catch, totaling 90 tails with a combined weight of 34,3 kg. The most effective hook is with a size of 15 mm.
Potential of Louhan fish (Amphilophus labiatus) as a local fishery pest in Lake Toba North Sumatra as a source omega 3 and 6 fatty acids
Authors: Pandiangan Maruba , Sihombing Dewi Restuana , Daniela Connie , Sibuea Posman , Tampubolon Sanggam Dera Rosa , Sitohang Apul , Sitanggang Lasmianna
Published: January 2025

Identifying the oil of Louhan fish (Amphilophus labiatus), which are now considered a nuisance and a danger to the native fish of Lake Toba, as a source of omega 3 and omega 6 fatty acids is the aim of the study. From August to November 2023, the research was conducted at the Faculty of Agriculture Laboratory at Santo Thomas Catholic University. The physical and chemical properties of Louhan fish oil, as well as its fatty acid content, were examined using a gas chromatograph. The physical and chemical analysis of Louhan fish oil revealed the following results: turbidity point 36 oC, total solids 34 oBrix, free fatty acid content 3.35 mg KOH/g, peroxide number 7.3 meq/kg, iodine number 45 mg/100g, and saponification number 198 mg KOH/g. The results of the gas chromatography study showed that the levels of unsaturated fatty acids were higher than those of saturated fatty acids. Furthermore, linolenic acid, an omega 3 fatty acid, and linoleic acid, an omega 6 fatty acid, were found in the analysis's results. Louhan fish oil may include omega 3 and omega 6 fatty acids, which are beneficial to human health, based on its fatty acid composition.
Productivity of Bottom gillnet fishing gear on fish landing results at Fish Landing Base (PPI) Ujong Seurangga
Authors: Rizki Purnama Nanda , Miswar Edy , Fitriani Riska , Maulinda Maulinda
Published: January 2025

The bottom gillnet is a passive fishing gear resembling a rectangle, designed with floats on the top and sinkers on the bottom. Evaluating the productivity of the bottom gillnets is crucial for assessing their effectiveness in catching fish. This study examines the productivity of bottom gillnets using two mesh sizes: 1 3/4-inch and 2-inch. Conducted in 2 months in 2024 at the Fish Landing Base (PPI) Ujong Seurangga, the research employed survey and interviews methods with purposive sampling. Data analysis included calculation of production value per trip and per unit length of the net. The findings reveal that bottom gillnets with a 1 3/4-inch mesh size achieved a productivity of 1,870 kg/trip, while those with a 2-inch mesh size recorded 3,975 kg/trip. Productivity per sheet of net was 0.1 kg/sheet for the 1 3/4-inch mesh size and 0,2 kg/sheet for the 2-inch mesh size. A total of 33 fish species were identified during the study. The 1 3/4-inch mesh size caught 30 species (436 fish, 27,878 kg), while the 2- inch mesh caught 24 species (393 fish, 58,944 kg). These results highlight the efficiency and selectivity of different mesh size for bottom gillnet fishing.
Improved growth velocity using a new liquid human milk fortifier in Very Low Birth Weight infants: a multicenter, retrospective study.
Authors: Moya Fernando Rodrigo , Fowler Jennifer , Florens Adrian , Dombrowski Jennifer , Davis Olivia , Blanks Tiffony , Gratton Austin
Published: January 2025

Objective: To compare growth outcomes and tolerance among very low birth weight (VLBW) infants receiving a new, liquid human milk fortifier (LHMF-NEW) or a human milk fortifier-acidified liquid (HMF-AL).
Study Design: Retrospective, multicenter study of 515 VLBW infants in three regional NICUs. The primary objective was to compare growth velocity (g/kg/day) during fortification between groups by repeated measures regression. Secondary outcomes of interest were feeding tolerance and the incidence of late onset sepsis, necrotizing enterocolitis and metabolic acidosis. Student’s t, ANOVA, Wilcoxon, and Kruskal-Wallis tests were used for numeric variables, or, chi-squared and Fisher’s exact test for categorical variables.
Results: No demographic differences were identified between the groups (HMF-AL, n= 242; LHMF-NEW, n= 273). Growth velocity during fortification was significantly higher in the group receiving LHMF-NEW, despite relatively similar total fluid, calorie or protein intake (p=. ). Feeding intolerance was comparable between fortifiers. Necrotizing enterocolitis and late onset sepsis did not differ between groups and metabolic acidosis was diagnosed less frequently with the LHMF-NEW. Anthropometric measures at discharge and length of stay were comparable.
Conclusion: Infants receiving human milk fortified with the LHMF-NEW had faster growth velocity during fortification, similar tolerance and less metabolic acidosis compared with an earlier cohort of infants who received human milk fortified with a HMF-AL.
Endocrine-Disrupting Chemicals and Female Reproductive Aging
Authors: Wu Jiaxin , Harlow Siobán D. , Randolph John F. , Gold Ellen B. , Park Sung Kyun
Published: January 2025

Female reproductive aging often affects women's emotional, physical, and physiological well-being. Ovarian aging is characterized by fluctuations in reproductive hormones and determines the age at which menopause occurs. Understanding potentially modifiable factors that influence this process is essential for addressing health disparities, improving quality of life, and informing relevant public health strategies. This review synthesizes in vivo, in vitro, and epidemiological findings about the effects of endocrine-disrupting chemicals (EDCs), specifically heavy metals and perfluoroalkyl and polyfluoroalkyl substances (PFAS) on female reproductive aging. Most in vivo and in vitro studies have demonstrated that heavy metals alter ovarian morphology, folliculogenesis, and steroidogenesis. Evidence regarding the effects of PFAS is limited and inconsistent. Epidemiological studies have consistently shown that heavy metals are associated with a higher risk of diminished ovarian reserve (indicated by decreased anti-Müllerian hormone) and earlier menopause, with limited findings regarding reproductive hormone changes. PFAS exposure has been associated with decreased estradiol and earlier menopause but not significantly with ovarian reserve. Gaps in the literature require more comprehensive epidemiological research on the effects of EDCs on female reproductive aging, including ovarian reserve, age at menopause, and vasomotor symptoms, to inform future interventions to reduce hazardous exposures and improve women's health.
Technical Review of Lithotripsy Devices for Percutaneous Management of Biliary Stones: A Guide for Interventional Radiologists
Authors: Mirza-Aghazadeh-Attari Mohammad , Kamireddy Arun , Jost Alec , Bwayili Hannatu , Singh Harjit
Published: January 2025

This review provides a comprehensive overview of intracorporeal lithotripsy techniques, focusing on laser and electrohydraulic lithotripsy, for the management of biliary tract stones. Biliary stones pose a significant health concern, affecting a notable percentage of the adult population, with potentially life-threatening complications. Minimally invasive approaches, such as lithotripsy, offer advantages over traditional, open surgical methods, including reduced risk of complications, shorter hospital stays, and faster recovery times. Laser lithotripsy employs light emission and amplification to fragment stones, while electrohydraulic lithotripsy generates shockwaves from a bipolar probe tip for fragmentation. Solid-state lasers like holmium and thulium fiber lasers are considered the gold standard, with recent advancements enhancing their efficiency and safety profiles. Safety precautions and patient preparation are essential for successful outcomes. Future directions for platform utilization may focus on optimizing parameters, exploring new therapeutic indications, and refining fiber designs. Overall, intracorporeal lithotripsy techniques represent valuable options for biliary stone management, improving patient care and quality of life through a minimally invasive approach.
Molecular dynamics simulations of functionalized hBN nanopores in water: Ab initio force field and implications for water desalination
Authors: Ghorai Sagar , Dhondi Pradeep , Govind Rajan Ananth
Published: January 2025

Heteropolar two-dimensional materials, including hexagonal boron nitride (hBN), are promising candidates for seawater desalination and osmotic power harvesting, but previous simulation studies have considered bare, unterminated nanopores in molecular dynamics (MD) simulations. There is presently a lack of force fields to describe functionalized nanoporous hBN in aqueous media. To address this gap, we conduct density functional theory (DFT)-based ab initio MD simulations of hBN nanopores surrounded by water molecules. The results reveal a high propensity for hydrogen (H) and hydroxyl (OH) functionalization at boron edges, while nitrogen edges are functionalized with H and occasionally with oxygen (O), highlighting a route to tune membranes. We demonstrate the role of the Grotthuss mechanism during the functionalization of hBN edges in water. We develop high-fidelity force fields for H- and OH-functionalized hBN nanopores using potential energy surface fitting based on DFT calculations. The nonbonded parameters for H functionalization are obtained by training a force field for borazine (B3N3H6). We find that the proposed force field enables stable MD simulations of water/ion transport through B- and N-terminated hBN nanopores. Our results also indicate that previous studies that considered bare nanopores without functional groups overestimated the water flux and underestimated the ionic rejection of nanoporous hBN. Overall, our work is expected to enable the realistic modeling of edge-functionalized hBN in aqueous media for various application areas.
Enhanced optical response of n-type doped InAs quantum dots through interface state inactivation
Authors: Liu Boyuan , Jia Xiansheng , Chen Hongmei , Ge Xiaotian , Lyu Menglu , Wei Chaoqun , Yu Ke , Ning Jiqiang , Zhang Ziyang , Jiang Cheng
Published: January 2025

Owing to the wide tuning range, high-temperature stability, flexible design, and fast recovery dynamics, quantum dots (QDs) have been widely used in many research fields, such as lasers, photodetectors, solar cells, and displays. Among these, III–V InAs/GaAs QDs are especially suited for infrared optoelectronic applications due to their strong working stability and enhanced light output efficiency. The doping technique has been admitted as a very effective method to enhance the modal gain and temperature insensitivity for InAs/GaAs QDs-based devices. Additionally, doping could modulate critical optical responses, like light absorption and carrier recovery dynamics, making these QDs ideal for ultrafast applications. In this work, p-type (Be) doping and n-type (Si) doping were introduced into multilayer QDs to mitigate the adverse effects of grown-in interface states, which were verified by temperature-dependent photoluminescence (PL) characterization. The results show a significant increase in PL intensity for n-doped samples, which was attributed to the effective suppression of interface states. This enhancement correlates with doping levels, with PL intensity increasing from 1.71 to 2.72 times as Si concentration rises from 1 × 1018/cm3 to 3 × 1018/cm3. In contrast, p-doped samples show a slight decrease in PL intensity and a 20 nm blueshift in PL emission peak, indicating different interdiffusion behaviors between In and Ga atoms compared to that in n-doped ones. By integrating with distributed Bragg mirrors, QD semiconductor saturable absorption mirrors were developed, where n-doped QDs presented superior performance in mode-locked ultrafast lasers with the shortest pulse width and highest output power.