bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Outcome Between Low Pressure and Standard Pressure Pneumoperitoneum in Laparoscopic Living Donor Nephrectomy
Authors: Tambunan Nicholas , Hamid Agus Rizal , Wahyudi Irfan , Mochtar Chaidir A
Published: June 2018

Nowadays, kidney transplantation is done through laparoscopic living donor nephrectomy performed by insufflating CO2 gas into intraperitoneum space using standard pressure (12–15 mmHg). However, it is also hypothesized that with lower pressure (8–10 mmHg) could
be used for laparoscopic living donor nephrectomy related with lower postoperative pain and side effects. This was a prospective comparative study done in Department of Urology, Cipto Mangunkusumo General Hospital from November 2015 to August 2016. All subjects underwent laparoscopic living
donor nephrectomy (LLDN). In this period, the subjects received a low pressure pneumoperitoneum procedure. This group was later compared randomly to a standard pressure pneumoperitoneum procedure group who underwent previous LLDN procedure. Out of 85, subjects underwent LLDN with low and standard
pressure were 41 and 44, respectively. Despite nonsignificant difference of post op pain and duration of operation, the side effect in low pressure was lower than standard (p = 0.033 for epigastric pain, p = 0.024 for nausea, and p = 0.018 for vomiting). However, 22% subjects with low pressure
need to be converted to standard pressure. Based on stratified analysis, the cause of conversion was higher BMI (p < 0.001). In conclusion, LLDN using low pressure pneumoperitoneum is proven to be as effective as LLDN using standard pressure pneumoperitoneum in providing good intraoperative
and postoperative outcomes. Thus, this study suggests the use of low pressure pneumoperitoneum as an alternative procedure in LLDN surgeries. Further studies, however, are needed to assess the adverse outcomes of LLDN procedure using low pressure, as well as to assess the risk of conversion
to standard pressure, i.e., BMI.
Compliance of Personal Protective Equipment (PPE) N-Series Mask Type 8211 and the Description of Lung Function of the Coal Mining Workers, PT. X, Kutai Kartanegara, East Borneo
Authors: Setiawan Felicia , Khazim Imron , Amri Zarni
Published: June 2018

Main hazard for the coal mining workers is chemical dust that will cause declining of lung function with chronic exposure. PT. X experienced elevated trend of decline lung function of its worker within the past three years (2013–2015 i.e., 15.8%, 18.3%, and 21.9%). November 2015,
PT. X stipulated new policy to its field workers that oblige them to use PPE mask of N series type 8211. Using cross sectional design with 300 people chosen by convinient sampling; primary data collection was conducted via interview and filling questionnaire, and secondary data collection
was compiled from PT. X’s MCU reports of 2015 and 2016 and HRD-HSE monthly reports. As much as 82% of workers are comply to use PPE. There are statistically significant relation between work motivation (p 0.02, ORa 4.80, 95% CI 1.22; 18.86), PPE knowledge (p < 0.01, ORa 353.77, 95%
CI 59.93; 2088.25), PPE comfortability (p < 0.01, ORa 61.64, 95% CI 5.99; 634.13), reward/punishment (p < 0.01), and supervision (p < 0.01, ORa 0.08, 95% CI 0.01; 0.43) with workers’ compliance of PPE mask of N series type 8211. There are three people experienced declining of
lung function within a year. PT. X was advised to continue its policy.
Computer Usage and Myopia Progression: An Evidence Based Case Report
Authors: Fransisca Rebecca Octavia , Vidiawati Dhanasari
Published: June 2018

As the technology advancement, we tend to work more using computer or another video display terminals (VDT). VDT usage often causes eyes problems (computer vision syndrome) or even refractive errors. This study aims to evaluate computer or VDT exposure as prognostic factor in myopia
regression among young adults. Literature review method using medical journal is conducted through three databases (PubMed, Cochrane, and Ebsco). Keywords used are myopia, myopia progression, computer, and job (including their synonyms). Thirty-two articles were collected. Through title and
abstract screening, filtering doubles, and exclusion, only three articles that can be critically appraised. Based on these articles, myopia progression proportion among the population is around 10,5% with myopia progression risk around −0,16 D annually. Myopia progression predictor factor
is near work (along with computer and VDT usage). Myopia progression is related with near work notably computer usage. Thus, near work exposure should be decreased to prevent myopia progression.
Contraceptive Vaccines and Pregnancy Prevention
Authors: Sunjaya Angela Felicia , Sunjaya Anthony Paulo
Published: June 2018

According to WHO, 80 million pregnancies each year are unintended and 45 million undergo abortion. There remains a continuing need for effective long-term contraceptives with minimal side effects. Contraceptive Vaccines (CV) thus provides an attractive solution due to its periodic intake,
high specificity, reversibility and minimal side effects. This review aims to evaluate the potential of contraceptive vaccines for pregnancy prevention based on journal articles obtained from PubMed, Elsevier Clinical Key and Google Scholar. CV works by using the body’s own immune system
to target molecules which take part in the reproduction process but do not confer other pleiotropic effects other than infertility. Three main mechanisms of CV are currently studied, namely by affecting gamete production, gamete function and gamete differentiation (hCG). Of all these, hCG
vaccines are of great interest as they are formed by early embryos, not the pregnant female hence providing the least side effects when inhibited. They are the first CV to pass Phase I and II trials successfully and found to remain effective as long as antibody titres stay above 50 ng/mL.
Those vaccinated can also easily undergo pregnancy when titres go below 35 ng/mL. Normal reproductive functions also remain following vaccination. An immunological approach to contraception remains an innovative idea and has been proven effective in both experimental and clinical trials. If
ongoing trials remain successful, CV will mark another progress in the field of mass contraception and its implementation would hopefully reduce the current prevalence of unintended pregnancies.
Craniofacial Parameters Cannot Predict Difficulty for Laryng Visualization in Children 1–4 Years Old
Authors: Wijaya Andi Ade , Ayuningtyas Risha , Kusumaningrum Dian
Published: June 2018

Airway assesment is an important measure to minimize airway complication, both in adults and children. Cormack-Lehane grading system is most widely used as guideline in predicting difficulty for larynx visualization in adults. However, not much had been found regarding guidelines for
children. This study was conducted to find the association between craniofacial parameters and Cormack-Lehane (C-L) Score in children. This study is an analytic-descriptive study conducted to find the most significant craniofacial parameters (lower lip mental, tragus – lip distance,
mental angle, mentohioid, and angulus distance) towards difficulty of larynx visualization in children aged 1–4 years old who had general anesthesia in Cipto Mangunkusumo hospital. The sample was obtained using the consecutive sampling method. Based on the inclusion criteria, we have
collected 295 patients with the consent from the parents. Difficulty in laryngoscopy (Cormack-Lehane III and IV) was found in 8.1% patients. There was no significant association beteween five craniofacial parameters and Cormack-Lehane score with p values of each craniofacial parameters of
0.679, 0.173, 0.590, 0.251, and 0.884, respectively. The craniofacial parameter explained in this study cannot be used as a measurement tool for predicting of laryngoscopy difficulty in children age 1–4 years old.
Ethics on Health Related Data Researches in Indonesia
Authors: Primanagara Risnandya , Sutisna Atik
Published: June 2018

There have been mindset changes when considering research on health data. In the past, health records were not considered as an ethical issue according to the declaration of Helsinki in Ethic Human Researches. But nowadays, the latest guidelines on ethics on health related researches
implemented to the health data. Indonesia was not fully apply this ethical research on health data, because of several reasons Multiple article described how to imply the latest ethical procedure on health related data, and reviewed to find the most beneficial for health data researchers in
Indonesia. Several methods are found to be beneficial, but somehow were not feasible to Indonesian culture. There are options, such as: consent/assent, anonymization, or use under a public interest mandate. Discussions: There is still no best solution for Health related data ethic in
Indonesia because somehow the procedures is unsatisfactory and problematic. Somehow, this ethical procedure is up to us to consider.
Histomorphologic and Immunophenotypic Profile of Marginal Zone Lymphoma
Authors: Maharani Maria Angela Putri , Harahap Agnes S , Hardjolukito Endang S. R , Ham Maria Francisca
Published: June 2018

Marginal zone lymphoma (MZL) is a type of indolent neoplasm, arising from B-cells in marginal zones of lymph nodes and extranodal tissues. Here, we studied the histomorphologic and immunophenotypic profile of MZL. Material and Methods: Samples were obtained from the immunohistochemistry
(IHC) archive of the Department of Anatomical Pathology in FMUI/CMH. The samples were cases diagnosed as MZL or mucosa-associated lymphoid tissue (MALT) lymphoma, during 2013 to 2016. Demographic profile, Hematoxylin-Eosin, and immunohistochemistry slides were analyzed. Thirty-three cases
of MZL were included. Median age of all cases was 56 year-old, with male patients outnumbering females by 54.5%. Extranodal tumours made up 78.8% (26 out of 33) cases, among these 21 cases (80.8%) were in the eye. Around 18.2% (6 of 33) of MZL cases had large-cell transformation areas. There
were 72.8% (24 of 33) cases showed predominantly diffuse patterns, with neoplastic cells in the form of small lymphocytes, centrocyte-like, monocytoid, and plasmacytoid cells. Lymphoepithelial lesions, large cells, and epithelioid histiocytes were found in 30.8% (8 of 26) cases; 18.2% (6 of
33) cases and 21.2% (7 of 33) cases, respectively. Vascular hyalinization was seen in 30.3% (10 of 33) cases. IHC results showed positive CD20 and negative CD3 in all cases. Cyclin D1 was negative in all available (25 of 25) cases. Low Ki-67 level (between 0–20%), was found in 72.7%
(24 of 33) cases. These results showed similarities and differences with currently available literature. Further research is required to explain the existing discrepancies. Regardless of tumour location, complete IHC panel is necessary for MZL cases, as well as translocation and clonality
examination.
How We Do Buried Penis Reconstruction in Children: A Novel Technique
Authors: Atmoko Widi , Situmorang Gerhard Renaldi , Wahyudi Irfan , Rodjani Arry
Published: June 2018

Buried penis is a pathology for which several reconstructive techniques are described. We described a novel technique involving complete separation of dartos fascia from the skin and penis and excision of dartos fascia until penile fixation to pubic region after complete degloving of
penis to eradicate the abnormal attachments of the dartos muscle to the corporal bodies and evaluated the efficacy and safety of our technique. From June 2009 and February 2015, 28 patients underwent surgical repair of buried penis with our novel technique. We administered a questionnaire
asking questions about penile size, morphology, and voiding status to evaluate parental satisfaction. The mean age of patients at the time of operation was 9.50±2.09 years, and the mean duration of follow-up was 23.27±16.75 months. The mean satisfaction grades for penile size,
morphology, and voiding function were improve (p < 0.05) (Fig. 2). The mean preoperative satisfaction grade concerning penile size was 0.82±0.76, and it improved postoperatively to 2.67±0.52 at the last follow-up (p < 0.001). The mean preoperative satisfaction grade for
penile morphology was 0.86 ± 0.55, which improved to 2.12±0.40 at the last follow-up visit (p < 0.001). The mean preoperative satisfaction grade for voiding function was 1.10±0.72, which improved to 2.94±0.86 at the last follow-up visit (p < 0.001). There
were no complications such as postoperative infection and tissue necrosis. Edema developed in 2 patients, but resolved spontaneously after 1 month. Our method of buried penis correction was found to be technically feasible and safe. It results in a good cosmetic appearance and excellent postoperative
satisfaction rates in terms of size, morphology, and voiding function. Further research is needed to understand its pathophysiology.
Knowledge, Attitudes, and Behavior of Reproductive Aged Woman Towards Visual Inspection with Acetic Acid (VIA) Test in Puskesmas Kecamatan Makasar
Authors: Wiraguna Andrian , Pinasthika Anyta , Hemasari Arlinda E , Sarena Ayu P. B , Amien Bagus R , Winarto Hariyono , Hayati Nur
Published: June 2018

Cervical cancer is one of the top cause mortality in female in Indonesia. Nowadays cervical cancer is the 2nd from 10 cancers with highest incidences in the country with 40.000 numbers of cases every year. Even in DKI Jakarta, the incidences of cervical cancer have reached 5919 cases
per year. The symptoms of cervical cancer only occur when it is already in late stadium. Therefore, productive age female should aware to do VIA test routinely to prevent the cancer. However, productive age female awareness to do IVA test still low especially in low education country like
Indonesia. This study aims are to see the relationship between knowledge with attitude, and behavior about VIA examination in married woman in Puskesmas Kecamatan Makasar, East Jakarta. This study is using cross-sectional method with 97 samples that are married woman that visit Puskesmas Kecamatan
Makasar, East Jakarta, who passed the inclusion and exclusion criteria. Data were collected by using questionnaire. Result: 66% of respondents have an average level of knowledge and only 5,2% who have a good level of knowledge about VIA test. The good attitude for doing VIA test was
up to 47,4%, however the behaviour of doing VIA test shows different result that 79,40% have bad behaviour. There is no significant correlation between knowledge with attitude and behavior about VIA examination (p = 0,323; p = 0,217). From the study, there is no correlation between knowledge
with attitude and behavior to do VIA examination.
Level of Knowledge, Attitude, and Behavior of Reproductive Women to Cervical Cancer in the Duren Sawit Sub-District Primary Health Centre in 2016
Authors: Devi Jean B. P , Aaron J , Catherina N , Hanna F. R , Ikhlas R , Wahyu G , Yuditya P
Published: June 2018

Cervical cancer is one of the most common gynecological problems. According to WHO, in 2012 there were 528.000 new cases of cervical cancer diagnosed resulting in 266.000 deaths, 90% of which occur in middle-to-low income countries. In Indonesia, there are 40.000 new cases of cervical
cancer each year, making it the most common cancer found in Indonesian women. The number of occurrences can be linked to knowledge, attitude, and behavior which are influenced by age, education, availability of information, and lifestyle. This research is aimed to evaluate the level of knowledge,
attitude, and behavior in reproductive age women concerning cervical cancer particularly within the area of Duren Sawit Sub-District Primary Health Centre to be used to establish a work plan with the end goal of reducing the occurrence of cervical cancer particularly within the area of Duren
Sawit Sub-District Primary Health Centre. This research follows a cross-sectional design using questionnaires filled by 85 respondents chosen with simple random sampling. Respondents are reproductive age women who visited Duren Sawit Sub-District Primary Health Centre. The data are processed
using SPSS using Chi-square test. The results yield significance in relation between level of education, cervical cancer knowledge and attitude towards early screening, but no significance in the practices. From those results, it can be inferred that despite the adequate knowledge and positive
attitude towards early detection of cervical cancer, there are still factors hindering the community from early detection practices such as screening and vaccination.
Osteogenic Potency of Secretome Bone Marrow Derived Mesenchymal Stem Cells: A Literature Review
Authors: Dilogo Ismail Hadisoebroto , Fiolin Jessica , Aprianto Petrus
Published: June 2018

Treatment of non-union bone healing has been an unsolved problem in Orthopaedic surgery despite many advances. The most commonly adapted concept is the diamond concept including the osteoprogenitor cells, osteoinductive proteins, osteoconductive scaffolds and mechanical stability. Recent
study groups worldwide have been studying the Mesenchymal Stem Cells as an adjunct to increase the bone healing process. However, newer literatures have shown that only few number of MSC transplanted will integrate. This paracrine mechanism is mediated by active secretion of cytokines, growth
factors and enzymes called the secretome which is produced as a byproduct during the process of MSC culture. The addition of secretome itself alone is predicted to have the similar effect as the transplantation of MSC with less cost needed, and easier to obtain. The effect of MSC secretome
has shown positive result on neurodegenerative disease, acute kidney disease, and cancer; but the effect on bone regeneration itself has never been studied. The MSC secretome have been proven to contain various cytokines (TGβ, some interleukins, GCSF, and many other cytokines)
and growth factors (VEGF, EGF, PDGF, IGF-1, IGF-II, PLGF, HGF, NGF, BDNF). We also suspect the osteoinductive profile of MSC secretome due to the existence of BMP-2 which can be analysed using the ELISA spectrophotometry. The osteoinductive profile of secretome MSC will be able to replace
the need of recombinant human BMP-2 (rhBMP-2) transplantation in treating bone defect and diminish the risk of excessive inflammation created by BMP-2 and also the carcinogenic potency.
Prediction Index of Levator Ani Muscle Avulsion After Vaginal Delivery: An Evidence-Based Appraisal
Authors: Santoso Budi Iman , Al-Fattah Adly Nanda , Surya Raymond , Hakim Surrahman
Published: June 2018

Pelvic floor dysfunction (PFD) due to vaginal delivery is related to tear of levator ani muscle (LAM) that potentially lead to the impairment of quality of life among women. A number of attempts to predict LAM injury after vaginal delivery had been conducted. This study aims to appraise
the accuracy of several prediction index determining LAM injury after vaginal delivery. We conducted a search in Cochrane Library®, Pubmed®, and Medline® with the keywords of “pelvic floor dysfunction” AND “vaginal delivery”
AND “prediction.” Critical appraisal determining the validity, importance, and applicability (VIA) was conducted by 2 independent authors. After 6 weeks to 3 months’ duration of follow up, the incidence of LAM avulsion was varied from 15.4% to 35.6% from three studies. Multivariate
analysis showed that forceps delivery, OASIS, and active second stage (OR 3.8; 3.1; 1.61; respectively) as the most influential factors for LAM incidence. Maternal age and time spent in active pushing were also contributed to LAM incidence. OASIS and second stage of labor could be used as
the most influential components of prediction index for LAM incidence. Prediction indexes for LAM incidence are developed. OASIS and second stage of labor are acknowledged as two most influential variables among three appraised studies.
Prevalence of Insomnia Symptoms and Predictive Factors Among the Employees at Central Government
Authors: Prasetyo Abet Sukoco , Soemarko Dewi S , Kusumadewi Irmia
Published: June 2018

Insomnia can be occurred by employees in both private and government. Central government agencies have an important role to the technical, administrative, and analysis of government affairs such as national assets and important documents. The purpose of this study was to determine the
prevalence of insomnia symptoms and the factors that have significant relationship of the employees central government agencies in Jakarta. The study design was cross-sectional involving 224 respondents. Retrieving data using questionnaires Insomnia Rating Scale (IRS). Other instrument used
was a questionnaire characteristics of the respondents, Stress Diagnostic Survey (SDS), Self Reporting Questionnaire 20 (SRQ-20), and Heart Rate Variability (HRV) analyzer SA 3000P. The prevalence of insomnia symptoms in the staff offices of central government agencies reached 50%, which reached
44.2% mild insomnia symptoms and moderate insomnia symptoms were 5.8%. In this study the factors that have significant relationship are structural position (OR 0,64; 95% CI 0,41–0,98), stressor qualitative work overload medium-heavy (OR 2,50; 95% CI 1,02–6,10) and emotional mental
disorders (+)/positive (OR 2,76; 95% CI 1,20–6,36). The study found that the prevalence of insomnia symptoms at the office employees of central government agencies in Jakarta is quite high.
Relationship Between Stroke’s Risk Factors with Daily Activities Using Modified Shah Barthel Index in Chronic Stroke Patient at RSCM
Authors: Rachmayanti S , Kusumaningsih W
Published: June 2018

Hypertension and diabetes mellitus are the most common risk factors of stroke.The study aimed to determine the relationship between stroke risk factors, hypertension and diabetes mellitus, with dependency of chronic stroke patients in Department of Medical Rehabilitation RSCM. The study
is conducted by using the analytical observational cross-sectional study. The samples used in this study were 44 respondents selected by quota sampling method. The relationship between variabels was analyzed by bivariate test Chi-Square and multivariate analysis: Logistic Regression. Based
on Chi-Square test, relationship between MSBI scoring with hypertension and diabetes mellitus as stroke risk factors, sequentiallly p = 0,122 and p = 0,002. Furthermore, Logistic Regression test suggested that hypertension and diabetes mellitus as stroke risk factors related
to MSBI scoring, respectively; hypertension p = 0,076 (OR 4,076; CI95 0,861–19,297) and diabetes mellitus p = 0,007 (OR 22,690; CI95 2,332–220,722). Discussion: Diabetes mellitus is the most prominent risk factor in severe dependecy of chronic stroke patients.
The Impact of Prenatal Chronic Auditory Stimulation to the Development of Chicken Embryos’ Hippocampus: What Have Been Done and the Established Protocol
Authors: Widiartini Catharina , Liem Isabella Kurnia , AuliaJusuf Ahmad , Furqonita Deswaty
Published: June 2018

Auditory stimulation can differently modulate the development of auditory system and hippocampus. Using chicken embryos make it possible for researchers to focus on examining the direct impact of chronic auditoric stress to the development of fetal brain, especially to hippocampus without
confounding factors from mother and placenta. We focus to review studies that examined the influence of prenatal chronic auditory stimulation exposure (both as environmental enrichment and as stressor) to the development of chicken embryos’ hippocampus. We wanted to gather information
on what have been done and the what would be the established auditory stimulation protocol. We searched all in vivo studies in chicken that used prenatal chronic auditory stimulation to observed the changes in the developing hippocampus. The comparison was made in terms of characteristics
of the studies, auditory stimulation regimen, parameters studied, results, conclusion and suggestion for further research. Eight studies fulfilled the selection criteria and were included in the analysis. Discussion: Researchers have been exploring the influence of auditory stimulation
in form of music, species-specific sound and noise to the developing chicken embrios’ brainstem auditory nuclei, auditory imprinting area and hippocampus. They have used moderate intensity (65 dB) and high intensity (110 dB). The hippocampal parameters observed were morphology, molecular/biochemistry
and behavioral/cognitive changes. Chicken embrios are representative for studying the impact of prenatal chronic auditory stimulation to the developing brain. Studies have convincingly shown the benefits of species-specific sound and music exposure and the negative effects of noise to the
developing hippocampus. However, further research are still needed to address some issues. In doing so, researchers may replicate the established auditory stimulation protocol that have been consistently used in the studies reviewed.
Waist Circumference, Waist-to-Height Ratio, and Waist-to-Hip Ratio Profiles of Under-Fives Children from a Cohort Study in Bogor
Authors: Susilo Mursid Tri , Salimar  , Khusun Helda , Bardosono Saptawati
Published: June 2018

Waist Circumference (WC), Waist-to-Height Ratio (WHtR) and Waist-to-Hip Ratio (WHR) were concerned as new screening indicators to detect obesity among under-fives children. Those data were compared to the Waist-to-Height Z-Score (WHZ) and Body Mass Index (BMI)-for-Age as the commonest
indicators. A cross-sectional study was conducted among 370 children age 24–59 months old, nested with the Bogor Child and Development (BCD) cohort study by Indonesian Agency for Health Research and Development, Ministry of Health. The subjects and area of the study were referred to
the BCD cohort study. ROC curved and z-score classification system were used to found the obesity cut-offs. There were disparity of WC, WHtR, and WHR indicators among children age 24–35, 36–47, and 48–59 mo (p < 0.05). Meanwhile, there were disparity between WC compared
to gender (p < 0.05), however there were not disparity for WHtR and WHR (p > 0.05). In addition, there was no difference proportion of obesity between WHtR and WHZ indicators (p=0.070). Meanwhile, WHtR (p=0.125) and WC (p=0.070) were no difference proportion compare to BMI-for-age. WC,
WHtR, and WHR showed difference proportion compare to WHZ and BMI-for-age (p < 0.05) according to Z-Score classification system (Z-score > 3 SD as obese). However, there were no difference proportion of obesity among all indicators if used Z-score>2 SD as obese category (p>0.05).
WC, WHtR, and WHR were different in specific age group, while WC was different among gender. WC and WHtR should be considered as screening indicators to detect obesity on children because closely significant compared to WHZ and BMI-for-age.
Neutrophil to Lymphocyte Ratio as a Predictor of Restenosis After Angioplasty and Stenting for Asymptomatic Carotid Stenosis
Authors: Dai Zhengze , Li Rongrong , Zhao Nan , Han Yunfei , Wang Mengmeng , Zhang Shuai , Bai Yongjie , Li Zibao , Liang Meng , Xiao Lulu , Ma Minmin , Liu Xinfeng , Xu Gelin
Published: June 2018

The inflammatory response plays a vital role in the development of in-stent restenosis (ISR) after carotid angioplasty and stenting (CAS). The neutrophil to lymphocyte ratio (NLR) has been suggested as a sensitive inflammatory marker. We explored the association between NLR and ISR in CAS patients. A total of 427 patients who underwent CAS were enrolled. Neutrophil to lymphocyte ratio was measured before the procedure. Clinical examination and radiographic evaluation were performed at 6 months and annually after the procedure. In-stent restenosis was defined as ≥50% stenosis in the treated lesion. Cox regression was used to identify predictors of ISR after CAS. Of the 459 arteries (in 427 patients) with CAS, 72 (15.7%) were identified with ISR during a mean follow-up of 14.6 (19.1) months (range, 0.7-120.7 months). Increased NLR (≥2.13) was significantly related to ISR in patients with asymptomatic stenosis ( P = .001). However, significance was not observed in symptomatic stenosis. On multivariate analysis, baseline NLR ≥ 2.13 (hazard ratio [HR], 2.74; 95% confidence interval [CI], 1.46-5.14), smoking (HR, 1.99; 95% CI, 1.11-3.58), residual stenosis (HR, 1.12; 95% CI, 1.09-1.15), and baseline glucose level (HR, 1.01; 95% CI, 1.01-1.02) were associated with ISR. Elevated NLR may be a predictor of ISR after CAS for asymptomatic stenosis.
Fatigue Among Adults With Type 1 Diabetes Mellitus and Implications for Self-Management: An Integrative Review
Authors: Griggs Stephanie , Morris Nancy S.
Published: June 2018

Purpose

The aim of this review was to integrate empirical and theoretical literature on fatigue among adults with type 1 diabetes mellitus (T1DM). A methodological review using an integrative approach was used. Databases MEDLINE via Pubmed, CINAHL, PsycINFO, and Science Direct were searched for peer-reviewed articles published in English from 2007-2017, using the following search terms and Boolean operators: “Type 1 Diabetes” and “Fatigue.” Of 199 articles initially retrieved, 14 were chosen for inclusion. These articles included 13 quantitative (7 cross-sectional, 2 cohort, 2 secondary data analyses, 2 experimental) and 1 qualitative phenomenology. Fatigue was identified as one of the most troublesome symptoms reported in persons with T1DM. Four main themes emerged: fatigue in T1DM is multidimensional and related to psychological, physiological, situational, and sociodemographic factors.

Conclusions

Fatigue is considered a classic symptom of hyperglycemia; however, there were minimal data to support the theory that fatigue is related to hyperglycemia or hypoglycemia. Studies on fatigue among persons with T1DM are limited to small samples and cross-sectional designs with few randomized controlled trials addressing fatigue and diabetes-related symptoms. Evidence is conflicting regarding the onset of fatigue among persons with T1DM and the relationship between fatigue and diabetes duration. The prevalence of fatigue is likely influenced by disease physiology, psychological stress, and lifestyle factors, but more research is needed to confirm these relationships as causal inference is unclear.
Father Absence and the Reverse Gender Gap in Latin American Education
Authors: DeRose Laurie F. , Huarcaya Gloria , Salazar-Arango Andrés
Published: June 2018

Recent work on gender differences in academic performance in wealthy countries highlights the importance of family structure: Boys’ education suffers more than girls’ education does when biological fathers are absent. We explored whether high rates of father absence in Latin America and the Caribbean might help explain why girls in the region have been more likely than boys to complete secondary school for decades. Data from the Demographic and Health Surveys instead demonstrated that the effect of father absence did not differ between boys and girls. The reverse gender gap in Latin American education cannot be explained by father absence compromising boys’ on-time progression at ages 9 to 14 more than girls’. In the United States and other high-income countries, boys are particularly disadvantaged by father absence in poorer households, but in Latin America and the Caribbean poorer households may have higher levels of promale bias that offset any similar pattern.
Efficient grounding of abstract spatial concepts for natural language interaction with robot platforms
Authors: Paul Rohan , Arkin Jacob , Aksaray Derya , Roy Nicholas , Howard Thomas M.
Published: June 2018

Our goal is to develop models that allow a robot to efficiently understand or “ground” natural language instructions in the context of its world representation. Contemporary approaches estimate correspondences between language instructions and possible groundings such as objects, regions, and goals for actions that the robot should execute. However, these approaches typically reason in relatively small domains and do not model abstract spatial concepts such as as “rows,” “columns,” or “groups” of objects and, hence, are unable to interpret an instruction such as “pick up the middle block in the row of five blocks.” In this paper, we introduce two new models for efficient natural language understanding of robot instructions. The first model, which we call the adaptive distributed correspondence graph (ADCG), is a probabilistic model for interpreting abstract concepts that require hierarchical reasoning over constituent concrete entities as well as notions of cardinality and ordinality. Abstract grounding variables form a Markov boundary over concrete groundings, effectively de-correlating them from the remaining variables in the graph. This structure reduces the complexity of model training and inference. Inference in the model is posed as an approximate search procedure that orders factor computation such that the estimated probable concrete groundings focus the search for abstract concepts towards likely hypothesis, pruning away improbable portions of the exponentially large space of abstractions. Further, we address the issue of scalability to complex domains and introduce a hierarchical extension to a second model termed the hierarchical adaptive distributed correspondence graph (HADCG). The model utilizes the abstractions in the ADCG but infers a coarse symbolic structure from the utterance and the environment model and then performs fine-grained inference over the reduced graphical model, further improving the efficiency of inference. Empirical evaluation demonstrates accurate grounding of abstract concepts embedded in complex natural language instructions commanding a robotic torso and a mobile robot. Further, the proposed approximate inference method allows significant efficiency gains compared with the baseline, with minimal trade-off in accuracy.
Pneumonia in a Captive Central Bearded Dragon With Concurrent Detection of Helodermatid Adenovirus 2 and a Novel Mycoplasma Species
Authors: Crossland Nicholas A. , DiGeronimo Peter M. , Sokolova Yulia , Childress April L. , Wellehan James F. X. , Nevarez Javier , Paulsen Daniel
Published: June 2018

A 4-year-old captive male central bearded dragon ( Pogona vitticeps) was presented for recurrent episodic dyspnea and anorexia with occasional expulsion of oral mucoid discharge. Despite empirical antimicrobial therapy and supportive care, the animal died and was submitted for autopsy. Defining histologic features included heterophilic and lymphocytic interstitial pneumonia, with occasional amphophilic intranuclear inclusions and prominent type II pneumocyte hyperplasia. Transmission electron microscopy revealed intranuclear 80-nm, nonenveloped, hexagonal viral particles within pneumocytes. Helodermatid adenovirus 2 (HeAdV2) was determined as the etiologic agent through pan-adenoviral consensus polymerase (PCR) chain reaction and sequencing. Nucleic acid from a novel Mycoplasma sp. (provisionally called Mycoplasma pogonae) was identified by pan-generic PCR targeting the mycoplasma 16S ribosomal RNA gene with sequencing and phylogenetic analysis. As bacteria morphologically consistent with Mycoplasma sp. were not observed by special stains and transmission electron microscopy, the detection of M. pogonae nucleic acid is of indeterminate significance; however, M. pogonae and HeAdV2 coinfection may have exacerbated disease.
Transformative learning experiences in mechanical engineering through mechatronics: From high school to college
Authors: Karkoub Mansour , Abdulla Shameel
Published: June 2018

For many years, educators at all levels have been trying to revamp their teaching styles to optimize the learning process. The availability of new virtual and technical instructional tools has led to significant increase in research in teaching methodologies whose outcome can be split into three categories: (1) lecture delivery, e.g. flipped classroom; (2) interactivity, e.g. instantaneous gathering of students’ feedback; and (3) technology in the classroom, e.g. using clickers and other gadgets. The focus of this article is on the latter; particularly, the use of technology in teaching concepts that are hard to grasp by mechanical engineering students. These include electromagnetism, semiconductors, design, controls, and system dynamics. The work presented here is based on data collected from activities with 10th and 11th graders, college sophomores, and seniors. The activities include two-week long Science, Technology, Engineering and Mathematics course and a regular semester long mechanical engineering technical elective. A remarkable level of engagement and participation was observed from the students which led to the successful design and construction of interesting devices and systems which earned them recognition by their colleagues, administrators, and industry visitors. In addition, the student enrollment in the mechanical engineering program has increased by 44% since the start of the Science, Technology, Engineering and Mathematics event for high school students in 2013.
The Housing Enabler instrument: Assessing threats to reliability and validity
Authors: Norin Lizette , Iwarsson Susanne , Haak Maria , Slaug Björn
Published: June 2018

Introduction

The Housing Enabler instrument, designed to measure housing accessibility, has not been used in samples with long-standing spinal cord injury. We aimed to investigate potential threats to the reliability and validity of the instrument when used among older adults with spinal cord injury.

Method

Cross-sectional data from the Swedish Aging with Spinal Cord Injury Study ( N = 123, injury levels C1–L5) were utilised. The potential effect on the reliability and content validity of the House Enabler was qualitatively considered and reviewed in an iterative evaluation procedure. To analyse the potential effect on construct validity, simulations adjusting accessibility problem scores for housing adaptations and use of mobility devices were conducted.

Findings

Considerable threats to the reliability and content validity of the Housing Enabler were identified. The simulated analysis of construct validity showed a modest overall effect on the accessibility problem scores, although this was substantial in some individuals.

Conclusion

Data collection and analyses of housing accessibility with the Housing Enabler in samples characterised by high frequencies of housing adaptations and/or use of mobility devices (such as powered wheelchairs) require particular attention. Further studies are needed to propose optimisation of the instrument for use in such contexts, followed by psychometric testing to maintain reliability and validity.
Breaking the Waves: Innovating at the Intersections of Economic Development
Authors: Lowe Nichola , Feldman Maryann P.
Published: June 2018

State and local economic development is often conceptualized as a series of successive waves, with each wave representing distinct policy priorities. In this study, we rework the standard wave metaphor to recognize the gains for regional economies when practitioners reach across established boundaries to work together to create a strategy mix. We present a case from North Carolina biosciences to demonstrate the contribution to regional industrial specialization when specialists combine their respective knowledge of entrepreneurship and industrial recruitment and coordinate development practice. More than an adjustment to tightening budget constraints or intensifying political demand, strategy mixing allows practitioners to extend and capture greater gains from state support for innovation. This case study provides an illustrative example for how other regions can advance innovative industry by bringing seemingly distinct development tools and targets into closer alignment.
Reducing Psychological Stress in Peripartum Women With Heart Rate Variability Biofeedback: A Systematic Review
Authors: Herbell Kayla , Zauszniewski Jaclene A.
Published: June 2018

Peripartum women are exposed to a variety of stressors that have adverse health consequences for the maternal–child dyad (e.g., impaired bonding). To combat these adverse health consequences, heart rate variability biofeedback (HRVBF) may be implemented by holistic nurses to aid peripartum women experiencing a high level of stress. A systematic review was completed using the guidelines established in the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. To be included in the review, studies had to meet the following criteria: (a) published scientific articles, (b) studies published in English, (c) experimental, quasi-experimental, or case reports, (d) use of HRVBF as the main treatment, (e) use of psychological stress as a dependent variable, and (f) studies published until December 2017. The major findings of this review can be described as follows: (a) HRVBF and psychological stress in peripartum women are related concepts, (b) peripartum women who completed HRVBF report a reduction in stress compared with participants who did not receive HRVBF, and (c) there is currently no information on the effectiveness of HRVBF on psychological stress in the first and early second trimester of pregnancy. Overall, this systematic review of the literature provides objective evidence that HRVBF may be a potential beneficial adjuvant treatment for stress management in peripartum women.
Late-Holocene climate and vegetation dynamics in eastern Lesotho highlands
Authors: Norström Elin , Bringensparr Caroline , Fitchett Jennifer M , Grab Stefan W , Rydberg Johan , Kylander Malin
Published: June 2018

The eastern Lesotho highlands are of considerable hydrological importance to southern Africa as a so-called ‘water tower’ for the surrounding region. Here, we contribute proxy-data inferring climate and vegetation changes over the past 1600 years, assessing in parallel inorganic and organic chemical analyses on a sediment core from Ladybird wetland, eastern Lesotho. Several proxies were used to determine changes in local vegetation dynamics, productivity, hydrology (δ13 C, δ15 N, C/N, TOC) and the input and source of the detrital components (Ca/Ti, CIA). The first part of the multi-proxy record (AD 400–800) shows stable terrestrial conditions and low detrital input, followed by higher variability in almost all proxies between ca. AD 900 and 1200. The δ13 C record infers a higher proportion of C4 vegetation, tentatively associated with higher temperatures during this phase, coeval with the Medieval Climate Anomaly (MCA). After AD 1200, local conditions change gradually from purely terrestrial, towards the typical wetland environment prevailing today. A higher proportion of C3 plants and possibly an increase in aquatic organisms within the organic matrix corresponds with decreasing detrital input, suggesting locally high available moisture in this part of Lesotho during the Little Ice Age (LIA). Although age-model constraints impedes a robust regional comparison, the inferred climate variability is discussed as a tentative response to enhanced mid-latitude cyclonic activity during LIA, and the variable MCA climate conditions as indirectly dictated by changes in solar activity.
The Impact of Utilitarian and Hedonistic Shopping Values on Sustainable Fashion Consumption: The Moderating Role of Religiosity
Authors: Razzaq Zohaib , Razzaq Ali , Yousaf Salman , Hong Zhao
Published: June 2018

The present study aims to elaborate whether sustainable fashion consumption is characterized by emotions or rational thinking and how religiosity influences the motive for the consumers to get involved in sustainable consumption behaviour. A mall intercept survey sampling technique was employed in a large metropolitan area of Pakistan. All scales were adapted from extant literature. It was found out that sustainable fashion is more of a utilitarian aspect of clothing than a hedonistic aspect of clothing. Moreover, religiosity has a strong moderating influence on the relationship between utilitarian and hedonistic shopping values and sustainable fashion consumption. The present study has significant implications for fashion retailers in the developing countries as they need to incorporate sustainability aspects into their production processes more so because developing countries encounter severe mismanagement or scarcity of natural resources. The present study is one of the preliminary researches to investigate sustainable fashion consumption patterns of consumers with distinct disparity between the underlying motives of consumption either catering to utilitarian functions or gratifying hedonistic purposes. Another novelty is examining the moderating impact that religiosity would have on hedonic and utilitarian shopping values towards shaping sustainable behaviour.
Development Transition of a Riverine Tribe: A Study of the Misings in the Brahmaputra Valley
Authors: Morang Hori Chandra , Barman Hemanta , Bezbaruah M. P.
Published: June 2018

Scheduled Tribes form one of the most disadvantaged segments of the Indian population. The developmental interventions, including the constitutionally guaranteed affirmative action, have had limited success in bringing up the standards of living of these groups. This article focuses on a riverine tribe, the Misings, whose livelihood and developmental challenges are compounded by the recurrent floods and riverbank erosion. It is based on a study of developmental transition of this tribe inhabiting on the banks of the river Brahmaputra and its tributaries in upper Assam. It analyses socio-economic transition process among the tribe driven by the progressive forces of the spread of education and resulting occupational diversification. The levels of progress are found to vary depending on the degree of vulnerability of settlement locations—those bearing the brunt of recurrent floods and riverbank erosion are lagging behind in development attainments. To make the transition process more expeditious and inclusive, institutional strengthening for better delivery of basic services is suggested.
Integrated structure and maximum power point tracking control design for wind turbines based on degree of controllability
Authors: Xia Yaping , Yin Minghui , Li Ruiyu , Liu De , Zou Yun
Published: June 2018

A linearization model is obtained for a three-bladed horizontal-axis wind turbine (HAWT) consisting of blades and a drive-train. Sensitivity analysis of the degree of controllability (DOC) and maximum power point tracking (MPPT) efficiency with respect to the structural parameters of wind turbines is discussed by numerical simulations. It is observed from the simulation results that higher MPPT efficiency can be achieved with the increase of DOC. Based on the observation, this paper proposes a new integrated design method based on DOC to design and optimize the structural parameters of a HAWT. The designed turbine is tested by the commercial simulation software of wind turbines named Bladed. It is observed from simulations that when using the identical MPPT control strategy, the wind turbine whose structural parameters are optimized for a larger value of DOC can achieve higher MPPT performance.