bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Chickpea, Banana Peel flour and Fenugreek Spice Flour on the Physico-Chemical Properties and Sensory Quality of Wheat Bread: A Review
Authors: Techane Alemu Tolcha
Published: May 2024

This paperis aimed to review the updated scientific information regarding the effect of bread made from wheat flour, chickpea, fenugreek and banana fruits flour and their effect on physicochemical properties and nutritional values. Bread is global stable food particularly for African people and Asian. However, most of time bread made from on wheat cereal and it is nutritional poor due to deficiency of essential amino acids such as lysine, methionine and threonine. Specially, addition of legumes is important to increase protein content of bread. Because of legume flours, contain amino acid composition and fiber content, are ideal ingredients for improving the nutritional value of bread and bakery products is high. For more improvement of nutritional quality of bread addition of fruits like banana fruit is good due to nutritional content of them. So, to get bread which has good physicochemical properties with high nutritional values addition of chickpea and banana fruits flour are very important. Legumes like fenugreek are also good source of protein and used as spice to increase sensory properties when they added at optimum level.Therefore, supplementation of wheat flour with inexpensive staples and local available grains such as fenugreek, chickpea and banana help in improving the nutritional quality of wheat products bread.
Novel Method of Essential oil Extraction from Spices
Authors: Meghwal Murlidhar
Published: May 2024

Essential oils have a wide range of industrial and pharmaceutical applications hence different novel technologies are recently being investigated to study the extraction of essential oils, enzyme assisted extraction is one of the recent green technology which is being studied extensively to see its effect on the yield of various components like essential oils and bioactive compounds. This review article summarises the spices in which enzyme-assisted extraction has been employed and its effect on the yield of the essential oil as well as the effect on the quality parameters of the oil, various studies, however, confirm that enzyme-assisted extraction increased the yield of the essential oil, which becomes a potential energy-efficient and cost-effective process and can be used at the industrial scale for a wide range of food, pharmaceutical applications.
An update on Bulimia Nervosa and its Management
Authors: Meghwal Murlidhar
Published: May 2024

Bulimia Nervosa is an eating disorder where a patient indulges in binging and purging. Various psy-chological treatments are available like Cognitive Behavior Theory (CBT) and Interpersonal psycho-therapy which focusses on combating the negative thoughts to prevent destructive habit. Pharmacolog-ical treatments like consuming antidepressants like selective serotonin reuptake inhibitors (SSRIs) play a major role in eating disorder (ED) therapy. Bulimia Nervosa and its effects on the body can be main-tained by increasing the serotonin levels. Serotonin level can be increased by increasing tryptophan, folic acid, omega-3 fatty acids, electrolytes like potassium, magnesium etc in the body. Pharmacologi-cal treatment may have its own side effects in the body like dizziness, agitation, insomnia etc. Thus, various natural ingredients and herbs can be used like soybean, turmeric, whole grains, ginseng etc., for the management of Bulimia Nervosa (BN). Introducing nano foods using nanotechnology and adding polyphenols for managing BN can be a new scope for the food industry as well as the nutraceutical industry.
Influence of Environmental Conditions on Yield of Agricultural Crops
Authors: Bakhriddin Abdsattarovich Kiryigitov
Published: May 2024

The article presents ideas about the need for agricultural technology for growing early-ripening varieties of winter wheat, taking into account soil and climatic conditions, individual feeding norms, and irrigation regime. Soil moisture has been studied as the main factor affecting the yield of winter wheat under irrigated agriculture. Additionally, the conditions for the use of organic waste from the production of fungi are studied, as well as the necessary technologies for its practical application.
Ultrasound-Assisted Extraction of Phenolic Compounds from Buriti (Maurtitia Flexuosa L. f.) Pulp
Authors: Nascimento-Silva Nara
Published: May 2024

Little has been discussed about the content and profile of phenolic compounds from buriti. The few studies found in the scientific literature diverge about these levels. So, aiming to propose a standardization in the method of extraction of phenolic compounds from buriti pulp and to facilitate the comparison between the results, this work aimed to validate the methodology of extraction of these compounds through an asymmetric factorial design. The optimal conditions for extraction of phenolic compounds in buriti pulp were evaluated in an asymmetric factorial study with three factors (solvent, number of extractions, and time). The extraction procedure consisted of adding the specific solvent to the sample, and submitting it to an ultrasound bath for different times. We concluded that the best treatment was the extraction with acetone in three steps of 30 min each, solid-liquid ratio of 1:10 (g:mL, m/v), using an ultrasonic bath at room temperature.
Review on the Prevalence and Associated Risk Factors of Parasitic Zoonosis in Ethiopia: Taeniasis
Authors: Terefe Kassa Samson
Published: May 2024

Parasitic foodborne infections of humans may involve both protozoan and helminth species of internal parasites. The route of infection is normally consumption of the parasite’s natural hosts as a human food item. Taeniasis is a parasitic zoonotic disease caused by the adult stage of large tapeworms that live in the intestines of human hosts. Bovine cysticercosis is a food borne disease caused by Taenia saginata with humans as the final host and cattle as the intermediate host. Infection of human by Taenia saginata occurs through ingestion of raw or undercooked meat containing Cysticercus Bovis while; infection of cattle with Cysticercus Bovis occurs through ingestion of Taenia saginata eggs. The parasite population of these species consists of three distinct sub populations: adult Tapeworms in the definitive host (man), larvae (Cysticercus or metacestodes) in the intermediate host (pigs or cattle), and eggs in the environment. The most common causative agent in Ethiopia is the beef tapeworm, Taenia saginata, which has the cow as its intermediate host. The other tapeworm that can cause taeniasis (Taenia solium) has pigs as its intermediate host, but they are not so common in Ethiopia. Taeniasis due to beef tapeworm is highly prevalent in Ethiopia due to the widespread habit of eating raw beef (kitfo in Amharic, Figure 38.5) and poor sanitary conditions. Defaecation in open fields in grazing lands, disposal of raw human sewage in rivers and its use as a fertiliser, facilitate the spread of taeniasis. The highest cases of taeniasis are found in the towns of Northern and Eastern Ethiopia.
Trend of raw milk collection, milk processing constraints and opportunities in Ethiopia
Authors: Gutema Ararsa
Published: May 2024

Ethiopia is awarded from nature with cattle resource that brings it to the first stage from Africa and fifth from the world. Dairy production in Ethiopia is mainly rural small farming system with low productive indigenous cattle breed and an animal having multipurpose usage. Modern dairy product processing industries still infant and mostly dominated by traditional milk and milk products processing, due to regardless attention is given for dairy processing sector in the Ethiopia. Although modern dairy processing industries emerged in different part of the country, there is no constant in number of dairy processing industries which is up and down throughout different years due to disintegrated milk supply chain, poor milk quality, informal marketing, limit milk product processing technology, limited infrastructure and sociocultural impacts etc. are some of the limitation factors. Traditional milk product produced in Ethiopia are fermented yoghurt, traditional butter and butter milk, ghee and Cottage cheese. Whereas, modern milk and milk products are pasteurized milk, different type of yogurt and different kind of cheeses. Although, there are milk collection and milk product processing development constraints in Ethiopia, unexploited livestock resources in the country will an opportunities of milk and milk products processing investment. There for, this review paper is attempt to indicate the available dairy products processing investments opportunities and technical and non- technical constraints of milk collection and milk products processing in Ethiopia.
Extraction and Evaluation of Bioactive Compounds (Anti-Stress Components) from Selected Tropical Spices using Microwave Assisted Technique
Authors: A.F. Ofoedum
Published: May 2024

Crude extracts (essential oils) were extracted using a microwave assisted extraction from dried Ginger, T. tetraptera, and M. myristica and subsequently evaluated. Quantitative phytochemicals and antioxidant activities were determined in the crude extracts. The saponins were found to be highest in ginger extracts (2.71) and differs significantly (p≤0.05) from other samples. Flavonoids, terpenoids, and tannins are highest in Monodora myristica with mean values of 14.33, 7.30 and 5.46 respectively but had the least in alkaloids (6.84). T. tetraptera had the highest in alkaloids and steroids with mean scores of 10.17 and 4.31 respectively and with significant differences (p≤0.05). Total phenolic compounds are highest in M. myristica (26.06) followed by ginger (23.26) and T. tetraptera (20.93). The crude extracts recorded high antioxidant activities (DPPH, FRAP, LIPID Peroxidation inhibition, and Nitric oxide scavenging activities), in relation to the control (Vit. C). The crude extract from M. myristica gave the highest DPPH value (56.61) while ginger extracts recorded the highest score for FRAP while the control (Vit. C.) had the highest lipid Peroxidation inhibition Therefore, tropical spices can be used to produce antistress nutraceutical beverages.
Knowledge, Attitude, and Practice on type 2 Diabetes Mellitus of Adult Patient using Data Mining Approach in Nigeria
Authors: Tolulope Grace Jayeola
Published: May 2024

Diabetes mellitus is a serious public health problem that leads to substantial disease and death rate. Diabetes has resulted into a lot of complications such as renal failure, retinopathy, and heart diseases and is accounted as the 7th leading cause of death worldwide. This study was carried out to determine the knowledge, attitude and practice of adult patient living with type 2 diabetes using data mining approach in Nigeria. The participants from this study were from secondary data obtained from different journals from seven states in Nigeria. Data were collected using data mining approach from numerous set of data to get hidden knowledge. Data was entered using IBM Statistical Package for Social Sciences (SPSS) and was analyzed using both descriptive and Chi-squared automatic Interaction detection (CHAID) analysis. CHAID was used to develop the decision tree model which is used for the prediction of the knowledge, attitude and practice. Result showed that the participants comprised 2070 participants of which 56.8% where female and 43.2% were male. The Socio demographic characteristics have been revealed to have a role in the knowledge, attitude and practice of type 2 diabetic patient in that it is found out that marital status is the major determinant of knowledge in type 2 diabetic patients because about 100% of adult patient with marital status had good knowledge of 89.8%, also education is the major determinant of attitude in type 2 diabetes patients and knowledge is the major determinant of practice in type 2 diabetes patients. The adult patient had good knowledge on type 2 diabetes of 59.5%, poor knowledge of 31.1% and fair knowledge of 9.5%. This study also shows that 47% of diabetes mellitus patient had good attitude. 8.6% had fair attitude, and 44.4% had poor attitude of the ailment. Also, the study also shows that 52.5% of type 2 diabetes mellitus had good practice, 21.9% had fair practice and 25.6% had poor practice. Therefore, this study concluded that majority of the patient had good knowledge of diabetes. Nevertheless, there is a need to educate patient on issues relating to diabetes mellitus and ensure compliance to the interventions needed in the management of type 2 diabetes mellitus.
Growth Performance of Broiler Chicken Fed with Mung Bean Sprouts as Feed Ration
Authors: A. Oñal Paulino
Published: May 2024

In the Philippines, organic farming is greatly promoted by the government. Producing an organic product is safer and more secure compared to the use of synthetic materials. In this study, mung bean sprout was used as a complement on a feed ration for the growth of broilers and its effect on feed conversion ratio. The growth of the broiler chicken is a significant factor in consumers' satisfaction. The study was laid out in a Complete Randomized Design (CRD). The birds were randomly distributed, into four (4) treatments and replicated three (3) times, with four (4) birds in for every replication. The different treatments were used in this study, as follows: Treatment 1 - 100% Commercial feeds + 0% fresh mung beans sprouts; Treatment 2 - 100% Commercial feeds + 5% fresh mung beans sprouts; Treatment 3 - 100% Commercial feeds + 10% fresh mung beans sprouts; and Treatment 4 - 100% Commercial feeds + 15% fresh mung beans sprouts. Overall results revealed that, Treatment 4 (100% Commercial feeds plus 15% fresh mung bean sprouts) has the highest body weight gain of 548.67 grams and the lowest feed conversion ratio of 1.74, revealing significant effects after 28 days of feeding broiler chickens with mung sprouts complimented feed ration.
Effects Study of Water Deficiency in Raspberry Varieties
Authors: Islamov Sokhib
Published: May 2024

This article provides information on the results of the study of water deficiency in leaf tissue of raspberry varieties. The leaves of raspberry varieties obtained from annual branches were identified in three periods, namely in June, July and August of the summer, when the plant has a high demand for water, at 6 am, at 1 pm and at 6 pm.
Review on the Economic Impacts of Lumpy Skin Disease of Cattle and its Prevention and Control Strategies in Ethiopia
Authors: Terefe Kassa Samson
Published: May 2024

Lumpy skin disease (LSD) is an infectious disease of cattle, caused by a Lumpy Skin Disease Virus. It is an economically important viral disease of cattle affecting all ages and breeds that can be prevented by vaccination in endemic regions including Ethiopia. LSD is an OIE listed disease because of considerable financial losses and in Ethiopia due to the endemic nature of LSD; the country is facing serious difficulties in exporting live cattle and their products. In addition, this situation contributes a negative impact on the national economic growth through the loss of meat and milk production and poor quality of skin and hides. Serious economic losses can follow outbreaks that have a high morbidity and high mortality rates of 40 percent or more have been encountered. There is no specific antiviral treatment available for LSD-infected cattle. The disease is now the problem of almost all the regions and agro ecological zones of Ethiopia. Major outbreaks of LSD have been occurred in different regions of Ethiopia. Two vaccines, however, Neethling and Kenya sheep and goat pox virus, have been used widely in Africa with success. Preventing movement the diseased animals along with vector control, regular annual vaccinations and awareness creation for cattle owners play great role in disease prevention and control. The disease outbreak was observed in the cattle regardless of previous vaccination with Kenyan sheep- and goat pox vaccine the occurrence of LSD outbreak scale, despite the use of a vaccination regime, is suggestive of vaccine failure. Apparent emerging vaccine failure is a serious problem for efficient control of LSD, as the disease has been manifested by high morbidity and mortality rates, regardless of vaccination status. Consequently continuous surveillance on the status of the disease and genetic information on circulating field viruses is mandatory in order to take effective measures for the control of the disease in the country.
Doum Palm Meal (Hyphaene Thebaica) and Partial Maize Substitution: Impact on The Blood Biochemical Indicators of Weaned Pigs
Authors: Olujimi John Alagbe
Published: May 2024

This study looked at how weaned pigs' blood biochemical indicators were affected when doum palm meal (DPM) was used in part lieu of maize. After being weaned at 28 days of age and weighing 7.40 ± 0.09 kg at birth, fifty Landrace × Duroc crossbred pigs were divided into divisions based on their body weights and given five distinct experimental diets. Over the course of a ninety-day fully randomized design experiment. Diets 1, 2, 3, 4, and 5 were fed 0 %, 5 %, 10 %, 15 %, and 20 % DPM in place of maize. The NRC (2012) states that the experimental diet satisfied the pigs' needs, and clean water was provided daily and at will. DPM had the following elements: manganese (0.91 mg/100g), zinc (0.72 mg/100g), copper (0.35 mg/100g), iron (5.60 mg/100g), calcium (371.20 mg/100g), potassium (966.31 mg/100g), phosphorus (206.19 mg/100g), magnesium (150.67 mg/100g), and zinc. The values of total serum protein, albumin, globulin, creatinine, alanine phosphatase, aspartate transaminase, sodium, potassium, calcium, phosphorus, and bicarbonate were not affected (P˃0.05) by the treatments, with the exception of the glucose level, which was higher (P˂0.05) in D1 than in the other treatments. It has been shown that DPM can partially replace up to 20% of maize without causing metabolic problems or adversely influencing the health of the animals.
Focus on the epidemiology, pathophysiology, diagnosis, and management of insulin dysregulation in horses
Authors: Odunayo Akinniyi Olumide
Published: May 2024

Because there are various inter-related disorders of insulin metabolism that all may contribute to the final result of hyperinsulinaemia, the phrase "insulin dysregulation" has become the most acceptable term to use when describing equine metabolic syndrome (EMS). Insulin dysregulation is widespread in horses, and it appears to be more prevalent in physically sedentary horses. Laminitis and hyperinsulinaemia have been linked, as have other components of insulin dysregulation. Diagnosis of insulin dysregulation should be done in stages, beginning with basal testing, which includes baseline values of insulin and glucose, and concluding with dynamic tests, which detect tissue insulin resistance and hyperinsulinaemia. Dietary adjustments are the key to weight loss in the majority of EMS horses. To encourage weight loss, the horse should be given around 1.25% of its body weight every day. Exercise not only aids equid weight loss but also improves insulin sensitivity. The exercise should be tailored to the specific horse, taking into account its breed, fitness level, and owner's resources. When an obese horse is unable to exercise owing to laminitis or when obesity persists after extensive exercise and dietary management, levothyroxine sodium and metformin hydrochloride can be given to help accelerate weight loss and increase insulin sensitivity. Insulin dysregulation is a defining feature of equine metabolic syndrome and has garnered attention due to its direct link to laminitis. There is need for an in-depth understanding of ID in order to prevent the development of clinical laminitis. The current study discusses the epidemiology, pathophysiology, diagnosis, and management of insulin dysregulation in horses.
Aflatoxin M1 contamination in milk: A serious issue to be tackled
Authors: Zahra Naseem
Published: May 2024

This comprehensive review addresses the critical issue of Aflatoxin M1 contamination in milk, emphasizing its presence, detection methods, permissible levels, and associated health risks. Aflatoxin M1, a carcinogenic byproduct of Aflatoxin B1, poses significant concerns for the safety of milk, a crucial source of essential nutrients. Regulatory standards from entities like the European Union, U.S. FDA, and FSSAI highlight the need for monitoring and controlling contamination to protect public health. The review extensively explores diverse detection techniques, with ELISA standing out for its speed and precision. Preventive measures, including inhibiting contaminated feed intake, vaccination strategies, and judicious feed usage, are discussed as effective means to minimize Aflatoxin M1 in milk. However, complete elimination remains challenging, leading to the exploration of additional detoxification methods. The review covers various approaches during milk processing, such as pasteurization, sterilization, and the potential roles of probiotics. Absorption materials like bentonite and activated carbon show promise in binding and removing Aflatoxin M1, while chemical approaches with ammonia and hydrogen peroxide are examined with a cautious note on potential risks. Novel detoxification techniques involving plant extracts, including black cumin, garlic, and broccoli, is highlighted for their antioxidant properties. In conclusion, this review provides a foundational understanding of the multifaceted challenge of Aflatoxin M1 contamination in milk, offering insights for future research and the development of effective strategies to ensure the safety and quality of this dietary staple.
Cardiovascular risk and nutrition, epidemiology and clinic: a review
Authors: Basta Domenico
Published: May 2024

Cardiovascular disease (CVD) is one of the main causes of morbidity and mortality in the world and especially in developed countries [i],[ii],[iii],[iv]. It is estimated that in the coming years Numerous factors influence the onset and progression of these diseases, particularly the diet. Diet and nutrition have been extensively studied as risk factors for major cardiovascular diseases such as coronary heart disease (CHD) and stroke and are also linked to other cardiovascular risk factors such as diabetes, hypertension and obesity. A healthy lifestyle, which includes a balanced and adequate diet, based on the latest scientific evidence can contribute significantly to the prevention and treatment of (CVD) with a massive reduction in public health spending., In this scientific review, we examine the preventive and therapeutic importance of an adequate diet in cardiovascular diseases globally.
Mango Peel: An Eminent Food Source
Authors: Jain N. R. Sinchana
Published: May 2024

India has been cultivating mangoes for over 4000 years, and among tropical fruits, mango stands out as the most popular dessert globally. The perishable nature of mangoes, characterized by a relatively short post-harvest lifespan, makes it an ideal fruit for processing. Indeed, mango processing generates a significant amount of peel as a by-product. However, this peel, often considered waste, contributes to environmental pollution as landfills. Interestingly the peel has emerged as an eminent and underexplored food source with a multitude of potential benefits. It can be utilized to create valuable post-harvest value-added products. This review systematically examines the nutritional composition, bioactive compounds, and functional properties present in mango peel. The peel of the mango fruit is found to be rich in dietary fibers, vitamins, minerals, and various phytochemicals such as polyphenols and carotenoids, which contribute to its potential health-promoting properties. Additionally, the antioxidant and antimicrobial activities associated with mango peel highlight its potential applications in food preservation and as a natural additive. The review also discusses the potential use of mango peel extracts in the development of functional foods and nutraceuticals. Furthermore, the sustainable utilization of mango peel as a value-added product aligns with the principles of circular economy and waste reduction. This comprehensive exploration of mango peel as a valuable food source underscores the need for further research and development to unlock its full potential, promoting a more sustainable and holistic approach to food utilization.
Antibacterial, Antifungal and Phytotoxic Pharmacological Profiling of Different Extracts of Lespedesea Gerardiana
Authors: Rehman Bushra , Ahmad Hajra Afira , Umar Aiman , Najaf Khan Dur-E-Najaf , Kashif Muhammad , Zada Numan Saleh
Published: May 2024

This study is based on phytochemical properties of L. gerardiana, as well as the pharmacological and biological activities of crude methanolic extract (Crd. MeOH Ext.) and other fractions. A range of pharmacological and biological activities, such as antibacterial, antifungal, phytotoxic, were examined in Crd. MeOH Extract and different plant fractions. The results of the pharmacological and biological examinations showed that the chloroform (CHCl3) fraction had good antibacterial activity against Salmonella typhi (48.0%), Bacillus cereus, Proteus merabilus (50.0%), and Klebsiella pneumoniae (57.1%). Also demonstrating strong (55.5%) antibacterial activity against S. typhi was the nâhexane fraction. Low phytotoxicity was demonstrated by the plant materials at 1000 and 100μg/ml concentrations.
Prescribing Practices of Broad-Spectrum Antibiotics in Tertiary Care Hospital
Authors: Ali Ahmad , Bakhtiari Maria Naz , Shahid Amna
Published: May 2024

Antibiotics are chemical substances produced by microorganisms. This study aims to find the prescribing practices of broad-spectrum antibiotics in tertiary care hospitals. It is a descriptive observational chart review of patients who have been prescribed broad-spectrum antibiotics in Lady Reading Hospital, Peshawar and data is collected using a standardized chart obtained from the World Health Organization and then analyzed using software such as Microsoft Excel and Statistical software. The results suggested that the frequency and percentage of the broad spectrum antibiotics are high and most broad-spectrum antibiotics prescribed are empirical. Furthermore, the study suggests that educational programs such as antibiotics stewardship programs should be utilized to educate the prescriber in the hospital, which aims to reduce the risks and various complications associated with the use of broad-spectrum antibiotics. Culture samples are required before administration of antimicrobials. Frequent reassessment of the patient's condition and antimicrobial therapy may be indicated.
Perception, Practice, Reasons, and Challenges for Drug Shortage in Community Pharmacies of Pakistan, Lahore
Authors: Saeed Hamid , Nabeel Muhammad , Zainab Pakeeza
Published: May 2024

Medication shortages are a global issue that disrupts pharmacy services and negatively impacts patient care. The Drug Regulatory Authority Pakistan (DRAP) has set a benchmark for the drugs and medication supply committee. This study was conducted in five key regions of Pakistan and found that 55% of physicians and pharmacists encountered medication shortages. This study aimed to assess the perception, practice,reasons, and challenges for Drug Shortage in community pharmacies of Pakistan, Lahore. It is a descriptive, cross-sectional study of 471 Community Pharmacists and Technicians in Lahore. The data was collected through a comprehensive instrument designed after an extensive literature review. There were significant differences in the frequency distribution between pharmacists and technicians based on gender, marital status, area of residence, education, type of retail outlet, and working experience. Factors contributing to shortages include supply issues, misunderstandings, regulatory issues, poor inventory trends, and price spikes.
Optimization of Pseudomonas putida SOL10 Biosurfactant Production Using Cost-Effective Substrates
Authors: Rehman Bushra , Aslam Sadia , Ahmed Safia , Ikram Hira
Published: May 2024

Natural resources as a substitute energy source in recent technological advancements have resulted in the production of biosurfactants. In order to reduce production costs and maximise yield, the current work replaces expensive yeast extract with less expensive substrates and optimises temperature, pH, and agitation. Pseudomonas putida SOL10 produced biosurfactants using a variety of substrates, such as red beans, molasses, whey, potato peels, olive oil, castor oil, crude oil, kerosene oil, and leftover cooking oil. These sources were utilised singly with an inducer, urea. Surface tension and oil displacement assays were used to measure the generation of biosurfactants. The combination of 1% potato peels, 2% leftover cooking oil, and 0.1% urea produced the highest amount of biosurfactant at 30ËC, 9.5 pH, and 150 rpm of agitation. There was a drop in surface tension of up to 29 mN/m with a 6.7 cm ODA zone.
Phytochemical and Pharmacological Investigation of Lespedesea Gerardiana
Authors: Rehman Bushra , Umer Aiman , Aman Muhammad Kashif , Hamid Hajra Afeera , Iqbal Danish , Khan Sanam Islam
Published: May 2024

The World Health Organization (WHO) is giving more prominence to promoting traditional medicine, particularly, in thirdâworld countries. The global market of medicinal plants is estimated at over US$ 60.0 billion which is expected to grow up to US$ 5.0 trillion by the year 2050. In Pakistan, the bill for the import of medicinal plants was worth US$ 31.0 million, whereas the export of medicinal plants could hardly reach US$ 6.0 million. In the world, 30% of the pharmaceutical preparations are manufactured from plants. Keeping in view the potential of the global and local market, we conducted our current research work entitled Phytochemical and pharmacological investigations of Lespedesea gerardiana” The present dissertation comprises: Pharmacological/Biological activities of crude methanolic extract (Crd. MeOH Ext.),various fractions and phytochemical study of L. gerardiana. Crd. MeOH Ext. and various fractions of the plant were investigated for various pharmacological/biological activities including, Brineâshrimp lethality, Haemagglutination, and Insecticidal and Antioxidant assay.
Growth, productivity and quality of colored capsicum (Capsicum annuum L.) as influenced by hybrids and plant growth regulators under controlled environment conditions
Authors: MAITRA SAGAR , SAIRAM MASINA , SANTOSH D. T. , GAIKWAD DINKAR JAGANNATH , SAHOO UPASANA
Published: May 2024

In developing countries like India, rapid urbanisation was under way and the diet habits of the people have been changing day to day. Under this transformation, a section of the population is focused on nutritional security where vegetables play a major role in daily diet. Among different vegetables coloured bell pepper which is commonly known as capsicum, has importance due to its nutritional quality and market demand. The quality and productivity of coloured capsicum can be improved by choosing the best performing hybrids and exogenous application of plant growth regulators. Considering the above, the present study was conducted from November to April of 2020-21 and 2021-22 at the Protected Cultivation Unit of Centurion University of Technology and Management, Paralakhemundi, Odisha under controlled environment conditions. The experiment was laid out in factorial randomized block design consisting of two hybrids, namely, Orobelle (yellow colored) and Bomby (red colored); and eight treatments of growth regulators which were GA3 @ 25 ppm, GA3 @ 50 ppm, GA3 @ 75 ppm, GA3 @ 100 ppm, NAA @ 20 ppm, NAA @ 40 ppm, NAA @ 60 ppm and NAA @ 80 ppm. A total of 16 treatment combinations were worked out in the experiment which were replicated thrice. The results of the experiment revealed that there was no significant variation among the hybrids cultivated with respect to yield attributes, yield, quality parameters and growth attributes excluding plant height and number of leaves per plant at 60 DAS and 90 DAS. However, there was a significant impact of plant growth regulators on growth attributes, yield attributes, yield and quality parameters. The application of NAA @ 80 ppm resulted in early flowering (43.8 days after planting). Moreover, the maximum number of flowers per plant (32.5 flowers/plant), flower to fruit ratio (52.9), fruits per plant (19.5) and weight of the fruit (133.6 g) recorded in GA3 @ 100 ppm application. There was a significant interaction effect among treatment combinations in fruit yield where the highest value was recorded in Bomby hybrid with GA3 @ 100 PPM application. From the study it may be concluded that cultivation of both the hybrids can be considered as per the fruit colour and market demand along with the application of GA3 @ 100 ppm under controlled environment conditions.
Emigrant Songs of Ukrainians in the Context of Scientific Research of Robert Klymasz (Canada)
Authors: Fedorniak Nataliia
Published: May 2024

The purpose of the research is to analyse the genre and thematic, musical component and peculiarities of the transformation of emigrant songs from the collections of folk songs Introduction to the Ukrainian-Canadian Immigrant Folklore Cycle and Ukrainian Folk Songs from the Prairies by R. Klimasz (Canada). The research methodology is based on the principles of objectivity, systematicity and historicism, which is supported by the historical and cultural approach. The musicological, textual, stylistic, and contextual analyses are applied, which reveal the musical, literary, historical and cultural dimensions of the evolution of emigrant songs, and also allow us to identify the transformation of emigrant songs in new socio-cultural conditions. The scientific novelty of the research lies in the introduction into scientific circulation of the collections of sheet music of the Canadian-Ukrainian folklorist R. Klymasz, which contain samples of emigrant songs of Ukrainians in Canada as authentic musical folklore of Ukrainian immigrants in the context of studying the transformation of the musical folklore tradition of Ukrainians in the North American diaspora. Conclusions. The emigrant songs collected and published by R. Klymash, created among overseas emigrants, are part of the cultural heritage of the Ukrainian diaspora in North America, which consists of epic stories, song lyrics, and humorous and satirical dance songs. The folk song materials clearly demonstrate the current themes, melodic, rhythmic and harmonic aspects of the musical component, and the contexts of performance. The musical and poetic style of the songs expresses the peculiarities of the music of the western region of Ukraine with its respective linguistic dialects. Examples of emigrant folklore reflect the diachronic development of the song culture of Ukrainians in the diaspora from the creation of emigrant songs as authentic examples of immigrant folklore with gradual modification to complete assimilation into another cultural environment, which is expressed in the change of content of the works, the use of macaronic elements in the texts, and later – melodic borrowings.
ANALYSIS OF EFEECTIVENESS OF CRITICAL CONTROL IMPLEMENTATION USING PLANNED JOB OBSERVATION IN DIVISION X PT. A
Authors: Kurniawan Ahmad Tahta , Djunaidi Zulkifli
Published: May 2024

International Council of Mining and Metals (ICMM) constructed a framework of Critical Control Management (CCM) to prevent fatality. PT A still experienced the accident with TRIR 0.168 in 2020 then increased 0.176 in 2021. This study aimed to assess the effectiveness of CC in Mining Industry Division X PT A. Semi-quantitative study with descriptive model conducted in Division X PT. A. Data collected according to 5 main variables, namely supervisory system, hierarchy of control implementation, control implementation, policy conformity, and hazards and risks compliance. Primary data was collected from 17 supervisors who had Planned Job Observation (PJO) responsibility through questionnaire and in-depth interviews. Secondary data was HIRADC collected from 11 departments. Data analysis was conducted by descriptive statistical analysis and content analysis. PJO result indicated 20.9% inadequate result related to work practice. Control effectiveness questionnaire signified adequate result for all 5 variables with very suitable result. In addition, in-depth interviews resulted in positive findings in all variables and negative findings for supervisory system, hierarchy of control implementation, and control implementation. Overall, the effectiveness of CC in Division X PT. A still needs to be improved, especially for the aspects of work practice control enforcement and workers’ attitude towards CC.
Alterações radiográficas em equinos da raça Puro Sangue Lusitano entre 3 e 4 anos - relato de caso
Authors:   Universidade de Franca, Silva Gabriela Oliveira Lamarca da , Pavan Ana Luíza Bernardes ,   Universidade de Franca, Morais Bianca Costa de ,   Universidade de Franca, Carrijo Micaela Silva ,   Universidade de Franca, Rosa Júnior Mazurquiedisk Nunes ,   Universidade de Franca, Casas Vitor Foroni ,   Universidade de Franca, Andrade Júnior Luiz Roberto Pena de ,   Universidade de Franca, Pereira Lucas de Freitas ,   Universidade de Franca, Almeida Maysa Barbosa de ,   Universidade de Franca, Vasconcelos Caio Rafael Siqueira ,   Universidade de Franca
Published: May 2024

The diagnosis of locomotor disorders in horses is of great importance, as they are limiting factors for the use of these animals in sports and for their trade. Calcification of the alar cartilage can occur due to physiological or environmental factors, without causing dysfunction to the animal, but fractures of this calcified cartilage can cause clinical signs of lameness. Just like calcification of the alar cartilage, osteochondritis dissecans is also another condition of multifactorial origin, being likely to affect any species of mammals that are in the growth phase. The use of complementary exams, such as radiographic exams, contributes favorably to diagnoses and facilitates the evaluation and classification of injuries, favoring the performance of activities and the trade of horses.
RNA Temelli Terapötik Yaklaşımlar
Authors: Korkmaz İsmail , Arslan Serdal
Published: May 2024

RNA temelli terapötikler, RNA moleküllerinin hücresel süreçlerdeki etki mekanizmalarının aydınlatılması ve gelişen teknoloji ile oldukça yüksek potansiyele sahip terapötik stratejileri oluşturmaktadır. Bu stratejiler, birçok hastalığın mekanizması, patofizyolojik süreçleri, teşhisi, tedavisi ve hastalığın önlenmesi konusunda yeni alternatifler sunmaktadır. Ayrıca daha önce ‘‘hedeflenemez’’ olarak bilinen birçok patofizyolojik yollara yeni kapılar açmaktadır. RNA bazlı terapötiklerin sağladığı çeşitli moleküler bazlı ajanlar sayesinde tedavisi yeterli düzeyde olmayan hastalıklara umut verici yeni tedavi yöntemleri geliştirlebilecektir. Günümüzde bilinen 16 adet FDA onaylı RNA terapötik ilaç klinikte kullanılmaktadır. Bunun yanında çok sayıda RNA terapötiği geliştirilme aşamasındadır ve bu durum yakın gelecekte birçok hastalık için yeni tedavi yöntemlerine kapı açacaktır. Bu derleme makalesinde halihazırda kullanılan RNA terapötik stratejilerinin mekanizması, sentezlenmesi, paketlenmesi, hedefe iletimi gibi konular araştırılmıştır ve bunun yanında aday terapötik stratejilere de değinilmiştir.
Психофизиологический вклад тренировок с отягощениями (TR) в лечении тревожного расстройства у молодых людей
Authors: Silva Wector Castro da , Dendasck Carla Viana , Oliveira Euzébio de
Published: May 2024

Физические упражнения могут представлять собой одну из очень доступных и полезных альтернатив лечения, не оказывающую вредных побочных эффектов на здоровье людей с тревожными расстройствами. Среди моделей упражнений, способных принести физиологическую и психологическую пользу, выделяется тренировка с отягощениями (TR). Поэтому целью данного исследования было описать психофизиологический вклад тренировок с отягощениями (TR) в лечении тревожного расстройства у молодых людей. С этой целью было проведено библиографическое обзорное исследование качественным путем путем исследования научных статей по рассматриваемой теме, опубликованных в следующих базах данных: Национальный центр медицины; (PUBMED/MEDLINE); SCOPUS; периодические издания CAPES; Виртуальная библиотека здоровья (BVS); Психология Бразилии (BVS); Научная электронная библиотека онлайн (SCIELO) и Science Direct с учетом исследований, опубликованных за последние 5 лет. В этом смысле данное исследование в базах данных проводилось посредством комбинации двух или более логических операторов, применяемых следующим образом: (resistance training; OR acute resistance training; OR chronic resistance training; OR psychophysiological disordes; OR anxiety; OR anxiety disorders; AND young adults whith anxiety disorders). В результате было отобрано пять научных статей, соответствующих критериям включения. Анализируя эти научные публикации и определяя их корреляцию и общие результаты между ними, можно сделать вывод, что ЛТ является очень эффективным терапевтическим вмешательством в уменьшении симптомов тревожного расстройства и может использоваться в качестве альтернативной терапевтической стратегии и что она дает заметные результаты. для уменьшения симптомов этого расстройства с немедленным, среднесрочным и долгосрочным ответом.
The Role and the (Lack of) Need for Silence in Worship
Authors: Paljević-Kraljik Judita
Published: May 2024

The author of this article explores whether there should be a space for silence in the worship of God in believers’ lives, church services and the part of the service in which God is praised with songs. To carry out the study, the author compared worship services of two churches in Zagreb – the Evangelical Pentecostal Church “Rock of Salvation” and the Church of Christ (on Kušlanova Street). The author analyzed the presence and role of silence, considering the non-use of musical instruments in the Church of Christ and concluded that the “empty” space in the church service between individual smaller parts is used in various ways. The author presented different definitions of silence or quietness, which nowadays for many no longer means absolute silence, by putting in dialogue the interviews with the pastors of the mentioned churches – Ratko Medan and Mislav Ilić – and the reflections of theologians and experts in the field of Christian services. The same problem is also put against the backdrop of modern times that are both unfamiliar and uncomfortable with silence.
Mercadotecnia digital y publicidad on line
Authors:   Universidad de Guadalajara, Díaz Pelayo César Amador , López Martínez Edgardo Flavio , González Monroy Roberto , Preciado Ortiz Claudia Leticia
Published: May 2024

La aparición de las nuevas tecnologías en las comunicaciones ha revolucionado la forma de hacer y entender la mercadotecnia en las organizaciones. Mercadotecnia digital y publicidad online es producto de una revisión analítica que describe el origen y la evolución de la mercadotecnia. A través de sus capítulos explica los elementos claves y las funciones de esta disciplina; elabora un comparativo entre lo tradicional y lo digital, y expone los conceptos básicos de la creatividad digital y ejemplos de cómo utilizar esta estrategia.
Formation Mechanism of Rail Corrugation for Modern Tram Lines
Authors: Wang Zhiqiang , Lei Zhenyu , Zhu Jianyue
Published: May 2024

In order to explain the phenomenon of corrugation on measured line sections of the modern tram, a numerical model of modern tram-track coupling has been established by utilizing the multi-body dynamics method, and the formation mechanism of corrugation has been studied from the perspective of wheel-rail contact creep. The results show that the smaller the curve radius is, the greater the probability of corrugation occurs. The corrugation wavelength range is 40 mm~50 mm, the wave depth range is 0.05 mm~0.1 mm, and the wave depth is relatively small compared with the corrugation wave depth of metro lines, which is in line with the characteristics of the light-load operation of the tram. The formation mechanism of corrugation on modern tram sharp curves can be described as wheel-rail contact creep saturation leads to the generation of corrugation, and the source of creep is related to the guiding mechanism of the longitudinally coupled independent wheelset bogie. The formation of corrugation on the straight line of the modern tram is related to the difference in wheel diameters between the front and rear wheelsets on the same side, which can lead to different longitudinal velocities, thus generating longitudinal creep forces and inducing rail corrugation.
Factors Affecting the Mental Health of Thai Medical Staff during the Second and Third Waves of the COVID-19 Pandemic: An Online Cross-sectional Survey
Authors: Anupansupsai Rungarun , Saisavoey Nattha , Supavekin Suroj , Ratta-apha Woraphat , Lortrakul Juthawadee , Hataiyusuk Somboon
Published: May 2024

Objective: This comparative study of the second and third waves of the COVID-19 pandemic aimed to: 1) examine the mental health status of hospital staff; 2) describe the associations among various factors that affect mental health; and 3) investigate the impact of COVID-19.
Materials and Methods: Data were collected from Siriraj Hospital staff using online questionnaires including demographics, staff characteristics, health behavior, readiness to handle COVID-19; COVID-19 impact; and the Thai version of the Depression Anxiety Stress Scales–21 (DASS-21).
Results: Depression, anxiety, and stress scores were significantly higher in the third wave. Living in a high-surveillance area, social distancing difficulties, health behaviors, and office work all impacted mental health in both waves. Demographics, infection exposure outside the hospital, awareness of social distancing, and readiness to work from home impacted only the second wave. Direct work with COVID-19 patients impacted only the third wave. The common stressors included living expenses, daily life changes, and disease prevention costs in both waves, with COVID-19 news having a greater impact in the third wave. Main daily life impacts were income, transportation, and disease prevention equipment in both waves, with food becoming more important in the third wave.
Conclusion: Mental health should be prioritized especially in severe waves, focusing on staff at high risk of infection, experiencing social distancing challenges, daily life changes, and having health problems. Disease protection should also be emphasized early on.