bluuebunny/crossref_metadata_2025 huggingface dataset:
Escapism and Excessive Online Behaviors: A Three-Wave Longitudinal Study in Finland during the COVID-19 Pandemic
Authors: Jouhki Hannu , Savolainen Iina , Sirola Anu , Oksanen Atte
Published: October 2022

Excessive online behaviors refer to harmful or disproportionate use of digital network applications. Such behaviors are likely to be associated with escapist motives. Our aim was to analyze whether escapism predicts excessive gambling, excessive gaming, and excessive internet use over time. A longitudinal sample of Finnish residents aged 18–75 years (n = 1022, 51.27% male) was surveyed at three time points during the COVID-19 pandemic in 6-month intervals: April 2021 (Time 1), October–November 2021 (Time 2), and April–May 2022 (Time 3). Of the original Time 1 respondents, 66.80% took part in the surveys at both Time 2 and Time 3. All surveys included measures for excessive gambling (Problem Gambling Severity Index), excessive gaming (Internet Gaming Disorder Test), and excessive internet use (Compulsive Internet Use Scale). Three escapism-specific questions were used to construct a dedicated escapism variable. Socio-demographic variables, alcohol consumption, and psychological distress were used as controls. The study was conducted with multilevel regression analyses using hybrid models. Our research showed that escapism had strong within-person effects on excessive gambling, B = 0.18, p = 0.003; excessive gaming, B = 0.50, p < 0.001; and excessive internet use, B = 0.77, p < 0.001 over time. The between-person effect of escapism was demonstrated on excessive gaming B = 0.91, p < 0.001, and excessive internet use B = 0.61, p = 0.036. Adverse societal events and uncertain times can manifest in excessive online behaviors motivated by escapism, highlighting a need to focus prevention efforts on healthy coping methods.
COVID-19 Rapid Antigen Tests: Bibliometric Analysis of the Scientific Literature
Authors: Yeung Andy Wai Kan , Parvanov Emil D. , Nawaz Faisal A. , Rayan Rehab A. , Kletecka-Pulker Maria , Willschke Harald , Atanasov Atanas G.
Published: October 2022

As the COVID-19 pandemic continues to disrupt health systems worldwide, conducting Rapid Antigen Testing (RAT) at specified intervals has become an essential part of many people’s lives around the world. We identified and analyzed the academic literature on COVID-19 RAT. The Web of Science electronic database was queried on 6 July 2022 to find relevant publications. Publication and citation data were retrieved directly from the database. VOSviewer, a bibliometric software, was then used to relate these data to the semantic content from the titles, abstracts, and keywords. The analysis was based on data from 1000 publications. The most productive authors were from Japan and the United States, led by Dr. Koji Nakamura from Japan (n = 10, 1.0%). The most academically productive countries were in the North America, Europe and Asia, led by the United States of America (n = 266, 26.6%). Sensitivity (n = 32, 3.2%) and specificity (n = 23, 2.3%) were among the most frequently recurring author keywords. Regarding sampling methods, “saliva” (n = 54, 5.4%) was mentioned more frequently than “nasal swab” (n = 32, 3.2%) and “nasopharyngeal swab” (n = 22, 2.2%). Recurring scenarios that required RAT were identified: emergency department, healthcare worker, mass screening, airport, traveler, and workplace. Our bibliometric analysis revealed that COVID-19 RAT has been utilized in a range of studies. RAT results were cross-checked with RT-PCR tests for sensitivity and specificity. These results are consistent with comparable exchanges of methods, results or discussions among laboratorians, authors, institutions and publishers in the involved countries of the world.
Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities
Authors: Ayeni Emmanuel A. , Aldossary Ahmad M. , Ayejoto Daniel A. , Gbadegesin Lanre A. , Alshehri Abdullah A. , Alfassam Haya A. , Afewerky Henok K. , Almughem Fahad A. , Bello Saidu M. , Tawfik Essam A.
Published: October 2022

Neurodegenerative and neuronal-related diseases are major public health concerns. Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal hormones and neurotransmitters are major determinant factors regulating brain structure and functions. The implications of environmental and climatic changes emerged recently as influence factors on numerous diseases. However, the complex interaction of neurotransmitters and neuronal hormones and their depletion under environmental and climatic influences on NDDs are not well established in the literature. In this review, we aim to explore the connection between the environmental and climatic factors to NDDs and to highlight the available and potential therapeutic interventions that could use to improve the quality of life and reduce susceptibility to NDDs.
Evaluation of Heat Stress Levels Inside Greenhouses during Summer in Korea
Authors: Jung Wongeon , Kim Hyocher
Published: October 2022

Farmers working inside greenhouses during summer are at risk of heat-related illness. In this study, we compared the dry-bulb temperatures (DTs) and the wet-bulb globe temperature (WBGT) index inside and outside greenhouses. We then determined the criteria for appropriate working and resting times inside greenhouses. The measurements were performed during the hottest period in 2020 and 2021 for two greenhouses, representative of those commonly found in rural areas. A direct-reading WBGT index meter was used for these measurements, and Automated Synoptic Observing System (ASOS) data were used to obtain regional DT data. DTs inside the greenhouses were significantly higher than the ASOS DTs (p < 0.001). In addition, the August WBGT index inside was significantly higher than that outside the greenhouses (p < 0.001). We found that the temperature during the period between 08:00 and 19:00 exceeded the international threshold of 28 °C for heat-acclimatized workers performing moderate-intensity work, above which heat stress becomes a concern. Our results revealed that the thermal index inside can be significantly higher than that found outside greenhouses. Therefore, when work is required inside greenhouses during the summer, stricter standards and safety measures should be considered.
Deathly Accidents While High-Altitude Mountaineering in the Swiss Alps—An Observational Analysis from 2009 to 2021
Authors: Gasser Benedikt
Published: October 2022

Background: High-altitude mountaineering has become more and more popular. While many enjoy the beauty of the highest parts of Switzerland, there are considerable risks, which can even result in death. This study analyzed fatal events while high-altitude mountaineering in the Swiss Alps. Materials and Methods: In this study, cases of emergencies while high-altitude mountaineering in the Swiss Alps were analyzed in the period from 2009 to 2021 from the Swiss Alpine Club (SAC) emergency registry. Fatal emergencies were identified and analyzed in detail. Results: In total, 5020 emergency cases were analyzed, and among them 303 deathly events where detected. Of the fatal emergencies, 261 cases (86.1%) were male and 42 (13.9%) were female. The average age was 53.2 ± 19.1 years. More than half of the emergencies were on a route to a classic four-thousander. Fatal events were most common on the Matterhorn, with 40 cases (13.2%); on the Mönch, with 18 cases (5.9%); and on the Piz Bernina, with 10 cases (3.3%). In 245 of the fatal emergencies (80.9%), a fall was the cause. The second most prominent cause was rockfalls, with 16 cases (5.3%), followed by stranding, with 10 cases (3.3%), and avalanches, with 9 cases (3%). Illnesses and crevasse accidents counted together for less than 5% of the fatal cases. Almost two-thirds of fatal falls occurred while descending. Concerning nationality, 30% were from Switzerland and more than three-fourths of victims were from the countries of the Alps. Discussion: We found that falls were the most common cause of fatal emergencies in the Swiss Alps. Concerning the fact that most of these emergencies occurred during descents, fatigue and inadequate focus (forgetting the risks of the descent after successfully reaching the peak) are potential reasons for the fatal events. This potentially resulted from a lack of acclimatization, insufficient physical fitness, and inadequate tour planning. Since most victims were from the countries of the Alps, training tours may be possible as a recommended preparation for more difficult four-thousander peaks.
Evaluation of the Ecological Environment Quality of the Kuye River Source Basin Using the Remote Sensing Ecological Index
Authors: Liu Qiang , Yu Feihong , Mu Xingmin
Published: October 2022

Landsat remote sensing images obtained from 2000, 2005, 2010, 2015, and 2020 were analyzed. The normalized vegetation index (NDVI), moisture index (WET), land surface temperature (LST), and normalized building-soil index (NDBSI) were extracted based on the four aspects of greenness, humidity, heat, and dryness. The Remote Sensing Ecological Index (RSEI) was calculated using principal component analysis to quantitatively analyze and dynamically monitor and evaluate the ecological environment changes in the Kuye River Basin over the past 20 years. From the perspective of spatial and temporal distribution, the ecological and environmental quality of Kuye River Basin had a downward trend from 2000 to 2020. The overall RSEI grade was medium or poor, and the average RSEI decreased. The proportion of excellent and good grade watershed areas decreased, whereas that of medium, low, and poor grade watershed areas increased over the study period. Spatially, RSEI decreased gradually from southeast to northwest. The degraded areas were mainly distributed in urban areas with frequent human activities. Conversely, the superior eco-environmental quality areas were mainly distributed in eastern sections of the watershed. Compared with 2000, the eco-environmental quality of the Yulin urban area and Shenmu County in the southern section of the watershed are worsening.
Influence of Contoured Insoles with Different Materials on Kinematics and Kinetics Changes in Diabetic Elderly during Gait
Authors: Shi Qiu-Qiong , Li Pui-Ling , Yick Kit-Lun , Jiao Jiao , Liu Qi-Long
Published: October 2022

Background: Alterations in the lower limb kinematics and kinetics of diabetic patients have been reported in previous studies. Inappropriate choices of orthopedic insole materials, however, fail to prevent diabetic foot ulcers and modify abnormal gait. The aim of this study was to quantitatively compare the effects of contoured insoles with different materials on the kinematics of and kinetics changes in the diabetic elderly during gait. Methods: There were 21 diabetic patients who participated in this study. Three-dimensional (3D) experimental contoured insoles constructed of soft (i.e., Nora Lunalastik EVA and PORON® Medical 4708) and rigid (i.e., Nora Lunalight A fresh and Pe-Lite) materials with Langer Biomechanics longitudinal PPT® arch pads were adopted. An eight-camera motion capture system (VICON), two force plates, and an insole measurement system—Pedar® with 99 sensors—were utilized to obtain the kinematics and kinetics data. The plug-in lower body gait model landmarks were used for dynamic data acquisition during gait. The corresponding data from five gait cycles were selected and calculated. Results: The range of motions (ROMs) of the ankle joint (p = 0.001) and knee joint (p = 0.044) were significantly influenced when the contoured insoles were worn in comparison to the barefoot condition. The joint moments of the lower limbs with maximum ankle plantarflexion during the loading response and maximum knee and hip flexions were significantly influenced by the use of contoured insoles with different materials in the diabetic elderly. The peak plantar pressure (PPP) of the forefoot (p < 0.001), midfoot (p = 0.009), and rearfoot (p < 0.001) was significantly offloaded by the contoured insoles during the stance phase, whilst the PPP of the rearfoot (p < 0.001) was significantly offloaded during the swing phase. Conclusions: The contoured insoles, especially those constructed with soft materials, significantly offloaded the PPP during gait—hence accommodating certain abnormal gait patterns more effectively compared to going barefoot.
Two-Dimensional Decoupling and Decomposition Analysis of CO2 Emissions from Economic Growth: A Case Study of 57 Cities in the Yellow River Basin
Authors: Kong Yawen , Liu Chunyu , Liu Shuguang , Feng Shan , Zhou Hongwei
Published: October 2022

Precise decoupling of CO2 emission and economic development holds promise for the sustainability of China in a post-industrialization era. This paper measures the energy-related CO2 emissions of 57 cities in the Yellow River Basin (YRB) during 2006–2019 and analyzes their decoupling states and dynamic evolution paths based on the derived general analytical framework of two-dimensional decoupling states to decompose their decoupling index using the LMDI method. The results show that (1) from 2006 to 2019, the economic growth and CO2 emissions of cities along the YRB are dominated by weak decoupling at an average contribution of 53.2%. Their dynamic evolution paths show fluctuations of “decoupling–recoupling” states, while the evolution trend is relatively ideal. (2) The factors of economic output, energy intensity and population scale inhibit the decoupling in most cities, which contribute 39.44%, 19.34%, and 2.75%, respectively, while the factors of industrial structure, carbon emission coefficient, and energy structure promote the decoupling in most cities in the YRB, with average contributions of −12.63%, −8.36%, and −0.67%, respectively. (3) The significant increase in the contribution of energy intensity is the main reason for the “Worse” path of cities, while the industrial structure and energy structure factors promote to the “Better” path of cities. This work satisfies the urgent need for the ecological protection of the YRB and opens new avenues for its high-quality development.
“Knitting Together the Lines Broken Apart”: Recovery Process to Integration among Japanese Survivors of Intimate Partner Violence
Authors: Kita Sachiko , Kamibeppu Kiyoko , Saint Arnault Denise
Published: October 2022

Objective: This study used narrative interviewing and grounded theory analysis to discover the phases of trauma integration for Japanese women who had experienced intimate partner violence (IPV). Method: We interviewed 23 Japanese women who had experienced IPV using the Clinical Ethnographic Narrative Interviews (CENI) from November 2017 to September 2018 in Tokyo, Japan. The data from 11 participants who had achieved trauma integration using the Trauma Recovery Rubric were analyzed using a modified grounded theory approach. Results: Six phases of the trauma integration journey after IPV were discovered: (1) Chaos, (2) Burning out, (3) Focusing, (4) Challenging, (5) Deepening insights, and (6) Re-building. The survivors described the processes of exploration of themselves and their reactions to their concurrent challenges. They focused on finding ways to protect, re-discover, and re-embrace themselves by healing from physical, psychological, and spiritual distresses. They also rebuilt relationships with others and acquired knowledge and skills to achieve a new life. Notably, the primary components of their recovery processes were changes in self-perception and self-interpretation of the trauma itself and its impacts on one’s life and within oneself from multiple angles. In addition, traditional Japanese norms and gender roles, such as beliefs concerning the “ideal life of a woman” and fear of not behaving differently from others, profoundly influenced their recovery process. Conclusion: This study highlights the importance of incorporating individuals’ cultures and their phase, needs, and personal self-development timeframes when developing trauma integration interventions.
Supporting Physical Activity for Informal Caregivers during and beyond COVID-19: Exploring the Feasibility, Usability and Acceptability of a Digital Health Smartphone Application, ‘CareFit’
Authors: Egan Kieren J. , Hodgson William , Imperatore Gennaro , Dunlop Mark D. , Maguire Roma , Kirk Alison
Published: October 2022

The COVID-19 pandemic has exposed how our global societies rely upon the care and support of informal (unpaid) caregivers: in the UK alone, there are an estimated 6.5 million informal carers. The caring role is not just precarious, it is often associated with high levels of stress, poor/deteriorating health and crisis points (hospitalisations, worsening of health). Fittingly, there has been much research in recent years focusing on mental health supports. A lesser explored area is physical health and physical activity. To address this, we conducted a real-world feasibility, usability and acceptability study of a novel codesigned digital health app for caregivers to improve levels of physical activity. Our study was designed to test the prototype app use for three weeks, following participants across questionnaires/in app data/qualitative data. Our findings (from 27 caregivers) highlights key knowledge gaps around physical activity—national guidelines were not reaching populations studies and behavioural change techniques hold promise to help support caregivers in the longer term. Our collective results support the acceptability, usability and feasibility of the Carefit app and warrant further investigation.
Relationships between Plasma Concentrations of Testosterone and Dihydrotestosterone and Geriatric Depression Scale Scores in Men and Women Aged 60–65 Years—A Multivariate Approach with the Use of Quade’s Test
Authors: Karolczak Kamil , Kostanek Joanna , Soltysik Bartlomiej , Konieczna Lucyna , Baczek Tomasz , Kostka Tomasz , Watala Cezary
Published: October 2022

The potential role of testosterone and dihydrotestosterone in the pathogenesis of depression in older subjects is poorly recognized and understood. The current study examines the symptoms of depression in males and females at the age of 60–65 using a short version (15 questions) of the Geriatric Depression Scale (GDS) questionnaire. Blood plasma levels of androgens were estimated by LC/MS/MS. Total GDS score calculated for males were not found to be significantly associated with plasma levels of testosterone or dihydrotestosterone. Older men with higher plasma testosteronemia were more likely to report being in good spirits most of the time, but more willing to stay at home than undertake outside activities. The men with higher plasma levels of dihydrotestosterone also perceived themselves as being in good spirits most of the time. Older men with higher testosterone were more likely to report having more problems with their memory than others. No significant associations were found between plasma levels of androgens and GDS scores in older women; however, some tendencies suggest that testosterone and dihydrotestosterone may act as antidepressants in older women.
The Technology-Oriented Pathway for Auxiliary Diagnosis in the Digital Health Age: A Self-Adaptive Disease Prediction Model
Authors: Hao Zhiyuan , Ma Jie , Sun Wenjing
Published: October 2022

The advent of the digital age has accelerated the transformation and upgrading of the traditional medical diagnosis pattern. With the rise of the concept of digital health, the emerging information technologies, such as machine learning (ML) and data mining (DM), have been extensively applied in the medical and health field, where the construction of disease prediction models is an especially effective method to realize auxiliary medical diagnosis. However, the existing related studies mostly focus on the prediction analysis for a certain disease, using models with which it might be challenging to predict other diseases effectively. To address the issues existing in the aforementioned studies, this paper constructs four novel strategies to achieve a self-adaptive disease prediction process, i.e., the hunger-state foraging strategy of producers (PHFS), the parallel strategy for exploration and exploitation (EEPS), the perturbation–exploration strategy (PES), and the parameter self-adaptive strategy (PSAS), and eventually proposes a self-adaptive disease prediction model with applied universality, strong generalization ability, and strong robustness, i.e., multi-strategies optimization-based kernel extreme learning machine (MsO-KELM). Meanwhile, this paper selects six different real-world disease datasets as the experimental samples, which include the Breast Cancer dataset (cancer), the Parkinson dataset (Parkinson’s disease), the Autistic Spectrum Disorder Screening Data for Children dataset (Autism Spectrum Disorder), the Heart Disease dataset (heart disease), the Cleveland dataset (heart disease), and the Bupa dataset (liver disease). In terms of the prediction accuracy, the proposed MsO-KELM can obtain ACC values in analyzing these six diseases of 94.124%, 84.167%, 91.079%, 72.222%, 70.184%, and 70.476%, respectively. These ACC values have all been increased by nearly 2–7% compared with those obtained by the other models mentioned in this paper. This study deepens the connection between information technology and medical health by exploring the self-adaptive disease prediction model, which is an intuitive representation of digital health and could provide a scientific and reliable diagnostic basis for medical workers.
South Korean Early Cancer Patients’ Perceptions of Difficulties in Fighting Their Disease: A Q Methodological Approach
Authors: Shim Min-Jeung , Lee Song-Yi
Published: October 2022

This study applied the Q methodology to explore breast cancer patients’ perceived difficulties in their fight against the disease. We used literature analysis and in-depth interviews and selected 162 statements for the Q population. Then, we chose 40 universal and representative statements for the Q samples from the Q population. The P sample included 13 breast cancer patients in the early stage of the disease who participated in the Q sorting. We interviewed the study participants with high factor weights by type of P sample. The study’s results showed three types of breast cancer patients’ perceptions of difficulties in the initial fight against the disease. Type 1 showed ‘fear of the future’, Type 2 showed ‘helplessness against what cannot be controlled’, and Type 3 showed ‘frustration due to difficulties in role performance.’ Based on these results, we discuss the characteristics, meanings, and significance of individual types of breast cancer patients’ perceptions of the disease, including suggestions for follow-up studies.
Evolutionary Analysis of Prefabrication Implementation in Construction Projects under Low-Carbon Policies
Authors: Shi Qianqian , Wang Ziyu , Li Boya , Hertogh Marcel , Wang Shuyi
Published: October 2022

In the context of carbon peak and carbon neutral policies, low-carbon construction has been the focus of most countries worldwide. As one of the most effective ways to achieve green construction, many countries have launched low-carbon policies to promote the development of prefabrication. However, the effectiveness and influencing factors of low-carbon policies on prefabrication need to be further verified under the dynamic game between the government and the construction enterprise. Therefore, this study considered subsidy and carbon tax policies and developed an evolutionary game model to promote the development of the prefabricated construction market. The evolutionary stable strategy of the government and construction enterprise under different scenarios was obtained. Subsequently, a numerical analysis was conducted to further investigate the impact of the key factors on the stable strategy. The results showed that an appropriate hybrid policy of subsidies and taxes could positively promote the prefabrication implementation of the construction enterprise. The government should adopt an appropriate policy intensity according to the maturity of the market. This study can provide effective guidance and practical enlightenment for the government to achieve low-carbon, green, and sustainable construction.
Favorable Adaptation during SARS-CoV-2-Pandemic as Told by Student-Athletes—A Longitudinal and Behavioral Study
Authors: Johnson Urban , Hertting Krister , Ivarsson Andreas , Lindgren Eva-Carin
Published: October 2022

(1) Background: The aim was to explore the impact of adaptive responses (resilience factors) on student-athletes’ behaviors during a stressful period of life during the SARS-CoV-2-pandemic of 2020 and 2021. (2) Methods: A constructivist-based grounded theory (CGT) was used guided by a biopsychosocial approach. Based on purposeful sampling, 22 male and female student-athletes were divided into four focus group interviews (FGI) seven months after the outbreak of the SARS-CoV-2-pandemic (October 2020) and 18 of these were followed up by FGI seven months later (May 2021). The mean age was 17.65 and they represented golf and handball. (3) Results: The CGT contained four main categories seven months after the SARS-CoV-2-pandemic outbreak: Social support, Self-discipline, Physical practice and recovery and Management of everyday life. Fourteen months after the SARS-CoV-2-pandemic outbreak, four additional main categories emerged: More extensive social support, Belief in the future, Self-awareness and Responsibility and problem-solving. (4) Conclusions: The CTG suggests that student-athletes’ favorable adaptations to the stressful SARS-CoV-2-pandemic period 2020–2021 are based on a gradually developed ability to take responsibility for one’s own actions, insight into the importance of deepened social interaction, belief in a positive post-COVID future and increased awareness of physical activity and its relation to perceived health.
The Body after Cancer: A Qualitative Study on Breast Cancer Survivors’ Body Representation
Authors: Sebri Valeria , Durosini Ilaria , Mazzoni Davide , Pravettoni Gabriella
Published: October 2022

Objective: The relationship with the body is a relevant issue for breast cancer survivors. Oncological treatments damage their bodies due to scars, weight gain, and other side effects. Starting from the efficacy of psychological interventions for breast cancer survivors, a tailored psychological support program was provided to promote overall well-being after illness dealing with bodily signals and related emotions and thoughts. This study presents changes in the description of the relationship with their bodies as well as participants’ emotions and thoughts before and after a psychological intervention. Methods and Measures: Eighteen women answered questions related to their bodies before and after the psychological intervention. Results were analyzed in accordance with the procedure of the Word Association Analysis through the T-Lab software and the Qualitative Thematic Analysis. Results: Participants reported a great awareness of their bodies and the desire to take care of them daily. In particular, the body is now perceived as a helper to sustain breast cancer survivors in their everyday activities. Conclusion: The words and the themes that characterized the participants’ reports highlighted the impact of cancer diagnosis and oncological therapies on breast cancer survivors. The participation in the psychological intervention focused on self-compassion towards their body helps women to create an improved body perception.
Changes in Couples’ Relationships and Their Differences in Type during the COVID-19 Pandemic in China
Authors: Jiang Qi
Published: October 2022

Purpose: This study explores changes in couples’ relationships during the COVID-19 pandemic, and analyzes the differences in the changes across three types: positive communication, criticism/defense, and demand/withdrawal. Method: A total of 600 (567 valid) Chinese respondents participated in this study, and a questionnaire was utilized to determine changes in their overall relationship, verbal and nonverbal communication, emotion, and activities with their spouses. Results: The average score of items related to positive communication is higher, compared with that of negative communication. Compared with the other two types of relationships, respondents with positive communication scored highest on all items related to positive communication and lowest on all items related to negative communication. Significant differences were noted between the positive communication types and the others. Conclusions: Results show that the relationships of couples included in this study have improved during the current pandemic. Therefore, improved consistency in the type of intimacy can lead to improved quality of couples’ relationships during the COVID-19 pandemic.
A Systematic Review of the Literature Examining the Effects of Cigarette Smoke and e-Cigarette Vapor on the Virulence of Human Pathogenic Bacteria
Authors: Bagale Kamal , Kulkarni Ritwij
Published: October 2022

The bioactive chemicals in cigarette smoke (CS) and e-cigarette vapor (EV) may affect pathogenic bacteria in the nasopharyngeal microflora, which may have implications on the pathophysiology of respiratory infections in cigarette smokers and e-cigarette users. In this systematic review, we seek to synthesize the research evidence supporting this hypothesis. To address the central research question, “what is known from the published, peer-reviewed literature about the effects of cigarette smoke or e-cigarette vapor exposure on the physiology of human pathogenic bacteria?”, we screened the PubMed®, Web of ScienceTM, and ScienceDirect databases for reports examining the virulence characteristics and gene expression in human pathogenic bacteria exposed to either CS or EV. The principal conclusion from our analysis is that exposure to either CS or EV induces the virulence of respiratory pathogenic bacteria in a strain-dependent manner, which may in turn facilitate respiratory infections in cigarette smokers and e-cigarette users. In addition, we present evidence that nicotine and reactive oxygen species are the main chemicals responsible for CS/EV-mediated alterations in bacterial physiology. We note limitations that this review does not examine reports describing the alterations in host respiratory physiology or nasopharyngeal dysbiosis caused by CS/EV exposure. Future research to determine whether CS/EV-mediated augmentation of bacterial virulence indeed plays a role in human respiratory tract infections is warranted.
Validation of the Flexible and Rigid Cognitive Restraint Scales in a General French Population
Authors: Péneau Sandrine , Bénard Marc , Robert Margaux , Allès Benjamin , Andreeva Valentina A. , Courtois Frédéric , Touvier Mathilde , Leys Christophe , Bellisle France
Published: October 2022

Distinguishing between flexible and rigid cognitive restraint (CR) may be useful for understanding the role of CR in dietary behavior and weight status. This study aimed to translate and adapt the flexible and rigid CR scales to the French context and test their psychometric properties. Construct validity, internal consistency, and test–retest reliability were examined in a sample of 620 individuals. Confirmatory factor analysis of the scales found a two-factor structure (flexible CR: 12 items; rigid CR: 15 items) that provided a good fit and supported the initial solution (χ2 = 584.7, df = 322, CFI = 0.96, RMSEA = 0.052 [0.045, 0.059], TLI = 0.95). Higher flexible and rigid CR were associated with higher CR overall, emotional eating (TFEQ-R21) and eating disorders (SCOFF), and lower intuitive eating (IES-2). In addition, higher flexible CR was associated with lower impulsivity (BIS-11) while higher rigid CR was associated with higher uncontrolled eating (TFEQ-R21) and lower self-esteem (RSES), satisfaction with life (SWLS), and optimism (LOT-R). Flexible and rigid CR internal consistency was satisfactory (McDonald ω = 0.77 and 0.74, respectively) and test–retest reliability was good (ICC = 0.81 and 0.79, respectively). This study validated a flexible and rigid CR tool in a French population and confirmed that these two types of CR represent distinct eating behaviors.
Exploring the Relationships of Financial Literacy and Financial Behaviour with Health-Related Quality of Life (HRQOL) among the Low-Income Working Population in Malaysia during the COVID-19 Pandemic
Authors: Sabri Mohamad Fazli , Said Mas Ayu , Magli Amirah Shazana , Pin Tan Maw , Rizal Hussein , Thangiah Nithiah , Ithnin Muslimah , Abdul Majid Hazreen , Ismail Rozmi , Su Tin Tin , Husniyah Abdul Rahim
Published: October 2022

This cross-sectional study examined the relationships of financial literacy (FL) and financial behaviour (FB) with health-related quality of life (HRQOL) during the COVID-19 pandemic among low-income working population (20–60 years old) in Malaysia. A self-administered questionnaire survey was used with HRQOL data were gathered using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) tool. A generalised linear model was employed to examine the hypothesised relationships between the constructs. From 1186 respondents, the majority were employed (73.9%), had a monthly household income of less than RM 2500 (74.5%), and did not have any chronic medical conditions (74.5%). The mean (SD) values of FL, FB, and EQ-5D-5L were 5.95 (1.48), 22.08 (4.79), and 0.96 (0.10), respectively. The results of the adjusted model revealed lower age group, Malay ethnicity, Indian ethnicity, and increased FB score as significant determinants of higher EQ-5D-5L scores. With the addition of the chronic medical condition factor into the saturated model, the lower age group, ethnicity, and no chronic medical condition were significant determinants of higher HRQOL. The effects of FB on QOL were confounded by chronic diseases, implying that interventions that focus on improving FB for those with chronic medical condition may help to improve the QOL among the low-income working population.
Effects of Yoga and Mindfulness Programs on Self-Compassion in Medical Professionals during the COVID-19 Pandemic: An Intervention Study
Authors: Miyoshi Tomoko , Ida Hiromi , Nishimura Yoshito , Ako Soichiro , Otsuka Fumio
Published: October 2022

Stress among healthcare workers (HCWs) increased during the coronavirus disease 2019 pandemic. We aimed to determine whether a yoga and mindfulness program could alleviate burnout and other psychological and physical distress in HCWs, and how this might affect their empathy for patients. A weekly one-hour yoga and mindfulness program was conducted for three months in 2021. Participants were 18 consenting HCWs and, the final analysis included 13 participants. They responded to online questionnaires before and after the program. We measured salivary cortisol levels before and after the program on the first and last days. Self-measured pulse rates (PRs) were taken before and after each session, which decreased significantly in both cases (before, after the first program: 72, 65 bpm, p < 0.05; before, after the last program: 75, 66, p < 0.05), but salivary cortisol levels did not change. No significant changes were observed in Patient Health Questionnaire-9, Maslach Burnout Inventory, Sense of Coherence, Connor-Davidson Resilience Scale, Self-compassion Scale, or Jefferson Scale of Empathy. However, common humanity, a subscale of self-compassion, increased significantly (before the first program: 5.6, after the last program: 6.5, p < 0.05), and over-identification decreased significantly (7.9, 6.7, p < 0.01). Yoga and mindfulness programs may help improve the sense of common humanity and reduce over-identification in HCWs.
The Impact of Meaningful Use and Electronic Health Records on Hospital Patient Safety
Authors: Trout Kate E. , Chen Li-Wu , Wilson Fernando A. , Tak Hyo Jung , Palm David
Published: October 2022

The HITECH Act aimed to leverage Electronic Health Records (EHRs) to improve efficiency, quality, and patient safety. Patient safety and EHR use have been understudied, making it difficult to determine if EHRs improve patient safety. The objective of this study was to determine the impact of EHRs and attesting to Meaningful Use (MU) on Patient Safety Indicators (PSIs). A multivariate regression analysis was performed using a generalized linear model method to examine the impact of EHR use on PSIs. Fully implemented EHRs not attesting to MU had a positive impact on three PSIs, and hospitals that attested to MU had a positive impact on two. Attesting to MU or having a fully implemented EHR were not drivers of PSI-90 composite score, suggesting that hospitals may not see significant differences in patient safety with the use of EHR systems as hospitals move towards pay-for-performance models. Policy and practice may want to focus on defining metrics and PSIs that are highly preventable to avoid penalizing hospitals through reimbursement, and work toward adopting advanced analytics to better leverage EHR data. These findings will assist hospital leaders to find strategies to better leverage EHRs, rather than relying on achieving benchmarks of MU objectives.
Impact of Sociodemographic Factors on Use of Formal Social Services in an Older Swedish Population
Authors: Stroh Emilie , Axmon Anna , Lethin Connie , Carlsson Gunilla , Malmgren Fänge Agneta , Mattisson Kristoffer
Published: October 2022

Background: In Sweden, societal support for older people is the responsibility of the municipalities. However, due to Sweden’s current aging-in-place policy for older people, there is a need to assess how the use of such services varies based on sociodemographic factors. The aim of this study was to describe the use of different forms of social services and institutional long-term care (ILTC) in an older population and to evaluate the impact of sociodemographic factors. Methods: This was a cross-sectional register-based study, including all individuals aged 65 years and older in two Swedish municipalities in 2010, 2015, and 2019. The study analyzed the use of social services and ILTC in relation to sex, place of birth, cohabitation status, and type of housing. Results: Women, those born in Sweden, and those living in an apartment were more likely to receive assistance than men, those born abroad, or living in single family houses, respectively. People living alone were consistently more likely to have assistance, as well as ILTC. Conclusions: There may be a discrepancy between the individual’s need and the assistance provided from the municipality in certain sociodemographic groups in the older population in Sweden.
Has the Risk of Outpatient Visits for Allergic Rhinitis, Related to Short-Term Exposure to Air Pollution, Changed over the Past Years in Beijing, China?
Authors: Li Sai , Wang Gang , Wang Beibei , Cao Suzhen , Zhang Kai , Duan Xiaoli , Wu Wei
Published: October 2022

A number of studies have found associations between the short-term exposure to ambient air pollution and hospital admissions. However, little is known about the temporal variations in ambient air pollution associated with health exposure, especially in China. We evaluated whether the risks of allergic rhinitis (AR) outpatient visits from short-term exposure to air pollution varied over time (2014–2020) in Beijing, China. A quasi-Poisson generalized additive model was used to evaluate the relative risks (RRs) and 95% confidence intervals (CIs) associated with the pollutant concentrations during the entire study period and three specific periods. We also analyzed the temporal variations of the period-specific associations and tested the trend of change using the Mann–Kendall test. The concentration-response relationships for the specific periods were further investigated. The RRs (95%CI) for an interquartile range (IQR) increased in PM10 (70 μg/m3) and CO (0.5 mg/m3) decreased from period 1 to period 3. However, The RRs (95%CI) of PM2.5 (55 μg/m3), SO2 (7 μg/m3) and NO2 (27 μg/m3) increased from 1.015 (0.978, 1.054), 1.027 (1.009, 1.044) and 1.086 (1.037, 1.137) in period 1 to 1.069 (1.005, 1.135), 1.074 (1.003, 1.149) and 1.214 (1.149, 1.282) in period 3, respectively. A statistically significant temporal change and the stable effects were observed between the NO2 exposure and AR visits over time. Despite a substantial reduction in ambient air pollution, the short-term effects on AR outpatient visits remained significant. Our findings provide a rationale for continued air pollution control efforts in the future to minimize air pollution and to protect the public.
Prevalence of Adverse Skin Reactions in Nursing Staff Due to Personal Protective Equipment during the COVID-19 Pandemic
Authors: Westermann Claudia , Zielinski Nika , Altenburg Christiane , Dulon Madeleine , Kleinmüller Olaf , Kersten Jan Felix , Nienhaus Albert
Published: October 2022

In order to prevent the nosocomial transmission of the SARS-CoV-2 virus, it has become necessary for health workers to increase their use of personal protective equipment (PPE). The aim of the study was to investigate the prevalence and influencing factors for adverse skin reactions (ASR) due to occupational PPE use among nursing staff in Germany during the COVID-19 pandemic. The study uses a mixed methods design. A focus group was created with experts from the field of healthcare, and an online survey was then carried out among nursing staff. Influencing factors were identified using multivariate logistic regression via odds ratios (ORs) with 95% confidence intervals (CIs). A total of 2274 nursing staff took part in the survey, with 1967 included in the analysis. The prevalence of ASR was 61%, with 94% affecting at least one area of the face. Statistically significant factors of influence were Filtering Face Peace (FFP) mask wearing duration of ≥4 h, a history of contact allergies, and being female and young. A pre-existing skin disease had a protective effect. The prevalence of PPE-related ASR underlines the necessity for targeted preventive measures for nursing staff during pandemic situation.
The Evaluation of Orthotics in Reducing Hallux Valgus Angle in Patients with Hallux Valgus over a Twelve-Month Treatment
Authors: Li Guoli , Shen Jinsong , Smith Edward , Patel Chetna
Published: October 2022

Background: Hallux valgus (HV) is one of the most common forefoot deformities among females, and its prevalence increases with age. This study aims to evaluate the effectiveness of three different types of orthotics on the reduction in hallux valgus angle (HVA) for patients with mild and moderate hallux valgus deformities. Methods: Twenty-six patients (42 feet) with mild or moderate HV participated in the treatment with three types of orthotics in the current study. Patients were divided into three groups depending on their HV severities and the consideration of different function of the orthotics. Orthotic Type 1 is a biomechanical style orthotic applied to moderated HV in Group 1. Orthotic Type 2 is a wrap style orthotic used on mild and moderate HV with two sub-groups: mild HV in Group 2A and moderate HV in Group 2B. Orthotic Type 3 is a gel style orthotic for mild HV. Patients were required to wear the orthotics for between 6 and 8 h per night over a period of 12 months. The HVA was measured every 3 weeks using a newly designed Measuring Block. A paired t-test was used to compare the differences between initial and final HVA at different stages of HVA treatment with orthotics. Results: After the 12-month treatment, for moderate HV patients treated with the Orthotic Type 1, their HVA reduced by 5.05° (95% CI 1.37, 8.73), (p < 0.05). For moderate HV patients treated with the Orthotic Type 2, their HVA reduced by 1.2° (95% CI −0.71, 3.11) (p > 0.05). For mild HV patients treated with the Orthotic Type 2, their HVA reduced by 2.44° (95% CI 1.39, 3.49) (p < 0.05). For mild HV patients treated with the Orthotic Type 3, their HVA reduced by 3.08° (95% CI −0.68, 6.83) (p > 0.05). Conclusions: Orthotic Type 1 showed a consistent significance in reduction in the HVA during the 12-month treatment, so it could be recommended for treating moderate HV. Orthotic Type 2 reduced the HVA, but it did not show a consistent significance in reduction in the HVA for mild and moderate HV. Orthotic Type 3 reduced the HVA, but it showed a volatile trend during 12 months without significant differences.
Epidemiology of Human Adenovirus in Pakistani Children Hospitalized with Community-Acquired Gastroenteritis under the Age of Five Years
Authors: Khan Nazif Ullah , Shamsullah  , Shahidullah  , Shah Aamer Ali , Zaidi Syed Sohail Zahoor , Chen Zhi
Published: October 2022

Acute gastroenteritis is the major cause of morbidity and mortality among infants and children around the globe. Along with other enteropathogens, human adenovirus (HadV) is a major etiological agent associated with diarrhea in young children. However, information about the epidemiology of Adenoviruses in Pakistan is limited or has not been reported. A total of 1082 stool samples were collected from patients with acute gastroenteritis under the age of five years with symptoms of diarrhea, vomiting, nausea, and abdominal cramps who visited Benazir Bhutto Hospital Rawalpindi and Children’s hospital in Lahore of Punjab Province in Pakistan. Of this, 384 cases with no blood in their stool, negative for Rotavirus, and under the age of five years were recruited in this study. Human Adenoviruses were isolated in the human epithelial HEp-2 cell line. Furthermore, adenovirus antigen detection was carried out by an enzyme-linked immunosorbent assay (ELISA), and then all positive and negative samples were confirmed by nested PCR. After inoculating a clear stool supernatant on HEp-2 cell lines, we observed a positive cytopathic effect in 65 (16%) cases. Using an enzyme-linked immunosorbent assay, HAdV antigens were detected in 54 (14.06%) of the clear supernatant from gastroenteritis cases. However, HAdV hexon coding regions were amplified in 57 (14.80%) fecal samples, mainly from patients ≤24 months of age. The findings of this study suggest that adenovirus circulates significantly in the children population under the age of five years and may be the potential etiological factor of acute gastroenteritis in the mentioned cities. This study provides baseline data about the possible role of adenovirus in causing viral diarrhea in children. Further large-scale epidemiological surveys are recommended to better understand disease burden, etiological agents, and its clinical impact across the country.
Sugar Tax or What? The Perspective and Preferences of Consumers
Authors: Piekara Agnieszka
Published: October 2022

Reducing high-calorie food and beverages consumption is a multi-dimensional challenge spanning agriculture to food marketing. Adverse health effects resulting from sugar-sweetened beverages such as obesity, diabetes, cardiovascular disease or dental carries have been described on numerous occasions. Poland is one of the countries that have introduced the sugar tax. The study aims to understand the degree of consumers’ awareness of the upcoming changes and their opinions and assessments of the efficiency of various activities. The study was based on Computer-Assisted Web Interview (CAWI). The sample comprised 500 adult consumers. Most of the respondents (69.6%) are aware that a new charge for sweetened beverages is going to be introduced, and for 78.9% of the respondents, it is important to take action aimed at reducing the consumption of sweetened beverages by consumers. Well-educated respondents as well as women perceive a greater degree of need to take specific action within the area of health policy (p-value 0.010 and 0.000 respectively). The sugar tax is considered an effective tool for limiting the purchase of sweetened products. Other types of activities within the framework of preventative healthcare that aim to reduce the consumption of sugar by society should also be developed.