bluuebunny/crossref_metadata_2025 huggingface dataset:
Préservation alvéolaire post-extraction à l’aide d’allogreffe (Maxgraft®) et réhabilitation prothétique fixe totale sur implants
Authors: Di Donna Edouard , Grange Yaelle , De Raemy Fanny , Keller Loïc Mahé , Perez Alexandre
Published: March 2024

Une femme de 69 ans a consulté l’Unité de chirurgie orale et d’implantologie des Hôpitaux Universitaires de Genève avec pour plainte principale des difficultés de mastication, une gêne esthétique et une bouche sèche. La patiente avait une sialadénite chronique non spécifique accompagnée de xérostomie. Elle portait une prothèse totale stabilisée sur deux implants interforaminaux et présentait de multiples caries des dents maxillaires res- tantes. Les objectifs du traitement étaient de réhabiliter la fonction masticatoire avec une solution prothétique fixe totale sur implants, en mini- misant au maxillaire la complexité chirurgicale, les morbidités post-opératoires et le nombre d’interventions à l’aide d’une technique de préservation de la crête alvéolaire post-extraction. Cette technique simple consiste à remplir l’alvéole post-extraction à l’aide d’un biomatériau/substitut osseux afin d’atténuer la perte volumétrique des crêtes alvéolaires liée à la résorption osseuse qui suit la perte des dents. Dans ce cas, la pose d’implants maxillaires a pu être réalisée avec une séquence de base sans augmentation osseuse, ce qui a réduit la morbidité, le temps de traitement et les coûts par rapport à la reconstruction de la mandibule édentée et atrophiée. En résumé, la préservation des crêtes alvéolaires post-extraction est une option thérapeutique prévisible qui pourrait être envisagée dans un contexte d’extraction multiple afin de limiter la complexité du traitement implantaire.
Orale Manifestation eines Mantelzell-Lymphoms
Authors: Peku Emir , Bassetti Mario A. , Kvint Rossana , Kuttenberger Johannes J.
Published: March 2024

Lymphome sind definiert als bösartige Neoplasien von reifen und unreifen B- und T-Zellen einschliesslich der natürlichen Killerzellen in unterschiedlichen Differenzierungsstadien. Diese treten vorwiegend im lymphatischen System auf. Eine Manifestation im Mundbereich ist selten. Nur ca. 3,5% der malignen Läsionen der Mundhöhle sind Lymphome. Da orale Lymphome regelmässig einen indolenten Verlauf ohne begleitende syste- mische Symptome aufweisen, kommt dem behandelnden Zahnarzt bei der Früherkennung dieses Krankheitsbildes eine besondere Bedeutung zu. In diesem Fallbericht stellen wir ein Mantel- zell-Lymphom bei einer 80-jährigen Patientin vor, das sich als eine orale Wangenschwellung klinisch manifestierte und somit zur Diagnosestellung führte. Die Biopsie als unabdingbares Mittel für die Diagnosestellung sowie die weitere onkologische Diagnostik und Therapie werden dargestellt und mögliche für den Privatpraktiker wichtige Differenzialdiagnosen diskutiert.
Schweizer Zahnmedizinstudium im Vergleich
Authors: Zeller Pascal , Zeyer Oliver , Brägger Urs
Published: March 2024

Im Jahr 2016 veröffentlichte die European Dental Students’ Association einen Press Release mit dem Inhalt, dass 10% der Studierenden der Zahnmedizin im EU-Raum keine praktischen Arbeiten am Patienten während ihrer Ausbildung durchführen. Um einen Vergleich mit der Situation in der Schweiz ziehen zu können, wurden die Absolventinnen und Absolventen der vier Zahnmedizinischen Kliniken in der Schweiz aus den Jahren 2015 bis 2018 zu ihrer praktischen Ausbildung befragt. Zusätzlich wurde untersucht, ob sich die Absolventinnen und Absolventen in der Schweiz gut auf die Arbeitswelt vorbereitet fühlten und in welchen Teilbereichen der Zahnmedizin eine vertiefte Ausbildung gewünscht worden wäre. Von den 34 verglichenen Behandlungen wurden 26 von den Studierenden in der Schweiz öfters durchgeführt. Erfreulich ist, dass sich über zwei Drittel der Studierenden gut auf die Arbeitswelt vorbereitet fühlten. Festzuhalten ist, dass eine vertiefte Ausbildung in den Bereichen der festsitzenden Prothetik sowie der Chirurgie gewünscht worden wäre.
Angina bullosa haemorrhagica – eine ungewöhnliche Blasenbildung in der Mundhöhle
Authors: Bornstein Michael M. , Von Arx Thomas , Baumhoer Daniel
Published: March 2024

Die Angina bullosa haemorrhagica (ABH; auch: Bullosa haemorrhagica oralis oder «benign hemorrhagic bullous stomatitis») wurde erst- mals von Badham im Jahre 1967 als rezidivieren- de Blutblasenbildung an der oropharyngealen Mukosa infolge mechanisch-traumatischer Irri- tation definiert. Ein möglicher Zusammenhang mit einer Vorschädigung der Mukosa durch all- gemeinmedizinische Befunde wie Hypertonie, Diabetes mellitus oder auch chronischer Ein- nahme von Kortikosteroiden über Inhalation konnte bisher nicht bestätigt werden.
Evaluation of antibacterial properties of fluoride-containing mouth rinses differing in their acidic compound using a Streptococcus mutans biofilm
Authors: Koegel Sally , Braissant Olivier , Waltimo Tuomas , Bornstein Michael M. , Astasov-Frauenhoffer Monika
Published: March 2024

This in vitro study assessed the antibacterial effect on Streptococcus mutans biofilms of mouth rinses with 700 ppm F- (derived from NaF) that differed only in their acid compounds (malic, citric, tartaric, fumaric, hydrochloric, phosphoric, and lactic acid) used to adjust pH.
S. mutans (ATCC™ 25175) was grown for 22 h at 37°C, harvested, resuspended in simulated body fluid and biofilm formation followed for 24 h at 37°C. Thereafter, biofilms were treated with experimental rinses for 30 s and placed in TAM48 isothermal microcalorimeter at 37°C for 72 h. Applying Gompertz growth model the parameters lag time and growth rate were determined from heat flow curves; additionally, reduction of active biofilms was calculated. Moreover, samples were live/dead-stained and analysed by confocal scanning microscopy.
All mouth rinses were showing statistically significant lag time and reduction of active biofilm (p < 0.05, A 19.1 ± 2.3 h and 58.5 ± 7.7%, B 15.5 ± 1.1 h and 41.9 ± 5.3%, C 17.6 ± 1.9 h and 53.1 ± 7.5%, D 18.4 ± 2.4 h and 55.8 ± 8.8%, E 20.2 ± 3.3 h and 61.5 ± 10.0%, F 20.2 ± 3.0 h and 61.6 ± 9.3%, and G 18.3 ± 2.5 h and 55.3 ± 8.9%). Interestingly, there were no differences found between the treated groups (p > 0.05, A 0.064 ± 0.004 1/h, B 0.063 ± 0.005 1/h, C 0.065 ± 0.004 1/h, D 0.067 ± 0.004 1/h, E 0.066 ± 0.006 1/h, F 0.067 ± 0.004 1/h, G 0.066 ± 0.006 1/h) for the maximum growth rate. Vitality staining supported these findings.
The present investigation demonstrates that the type of acid compounds used to produce the rinses did not show any negative effect on the antimicrobial properties of the tested products as all of them exhibited a similar efficacy against S. mutans biofilms.
Direkte Restaurationstechnik im Seitenzahnbereich zur Versorgung von erosionsbedingtem Zahnhartsubstanzverlust
Authors: Attin Thomas , Schmidlin Patrick R. , Tauböck Tobias T.
Published: March 2024

Der restaurative Aufbau verlorengegangener Zahnhartsubstanz und die Wiederherstellung der ursprünglichen vertikalen Bisslage bei einem durch Zahnerosionen oder -abrasionen stark in Mitleidenschaft gezogenen Gebiss stellt den Zahnarzt immer wieder vor Probleme bei der Um- setzung der Therapie. Traditionellerweise erfolgt diese Therapie mit laborgefertigten Werkstücken, die in der Regel eine Präparation der verbliebenen Zahnsubstanz erfordern und für den Patienten hohe Kosten verursachen, sodass alternative Verfahren in Betracht gezogen werden sollten. Dabei gilt es hervorzuheben, dass auch minimalinvasive restaurative Arbeiten bei diesen Patienten nur dann indiziert sind, wenn der präventive Ansatz, weiteren Zahnhartsubstanzverlust zu verhindern, gleichzeitig erfolgreich ist. Der folgende Beitrag stellt die Verwendung direkter adhäsiver Kompositrestaurationen als eine Möglichkeit zur Rekonstruktion einer erosiv stark veränderten Gebisssituation anhand eines Falles dar. Zur Rekonstruktion der Okklusalflächen werden dabei Übertragungsschienen eingesetzt, die auf der Basis von individuellen Wax-up-Modellen angefertigt werden.Das beschriebene Verfahren stellt eine gut untersuchte und erprobte Methode zur Versorgung von Zähnen mit erosionsbedingtem Zahnhartsubstanzverlust dar. Wie bei allen neuen Verfahren wird sich für den praktischen Zahnarzt eine gewisse Lernkurve ergeben, nach der hochwertige Restaurationen mit dieser Technik umgesetzt werden können.
Papilloma excision. Scalpel or CO2 Laser? A case report
Authors: Di Giovanni Tamara Marcella , Bosshard Fabienne Andrina
Published: March 2024

A papilloma is a benign tumor arising from an epithelial surface. Mostly a papilloma appears as an asymptomatic intraoral lesion and is often associated with the human papilloma virus (HPV). In this case report two similar, verrucous papules, sessile bilateral on the back of the tongue, were surgically removed in a 65-year-old male patient. Thereby two different methods of treatment were compared. On the right side of the back of the tongue, excision by scalpel, as the gold standard treatment modality, was performed. On the left side a surgical removal by a CO2 laser was performed. In a photothermal procedure, without direct contact to the tissue, the laser beam is cutting through the mucosa. Secondary wound healing can take place. Both methods were compared in relation to their application, wound healing, quality of the biopsy and morbidity. Postoperative less discomfort and a slightly faster wound healing could be seen after scalpel removal. The histopathological examination was comparable for both methods.
A survey on toothbrushing practices and dosing of fluoridated toothpaste among preschool children in the cantons of Basel-Stadt and Berne, Switzerland
Authors: Adé Désirée Céline , Filippi Cornelia , Filippi Andreas
Published: March 2024

This study aimed to evaluate toothbrushing practices and toothpaste dosing among preschool children aged 0-6 years in Switzerland recruited from the Department of General Pediatric and Adolescent Dentistry, University Center for Dental Medicine Basel UZB, and in daycare centers or in private practices located in the canton of Berne. Three hundred parents of children were surveyed about socioeconomic characteristics, their children’s toothbrushing behavior, the use of age-appropriate toothpaste, and whether they were instructed by an oral healthcare professional about appropriate toothbrushing practices and the amount of toothpaste to use. Additionally, the parents were asked to apply toothpaste to two different toothbrushes, one with a narrow and one with a wide brush head, as they usually would at home. The amount of toothpaste was weighed using a portable scale. Over 50% of the parents were not instructed by an oral health care professional on toothbrushing practices and toothpaste dosing. However, nearly all participants used age-appropriate toothpaste. Approximately 50% of the parents of 0- to 2-year-old children applied more than the recommended 0.25 g of fluoridated toothpaste (both brushes, mean ± SD: 0.25 g ± 0.14 g), while two-thirds of the parents of 2- to 3-year-olds (both brushes, mean ± SD: 0.36 g ± 0.23 g) and nearly 90% of the parents of 3- to 6-year-olds applied more than 0.25 g (both brushes, mean ± SD: 0.43 g ± 0.20 g). Overall, parents dispensed more toothpaste on the toothbrush with the wide brush head. The present study suggested that assuming toothpaste as the sole source of fluoride, the amounts generally used are not of concern. However, considering the substantial variation in the amounts of toothpaste applied, oral healthcare professionals should routinely provide instructions on toothbrushing practices and toothpaste dosing during children’s dental examinations.
PROCESSING OF SQUID (Loligo sp.) CARTILAGE WASTE AS ANTIBACTERIAL HANDWASH
Authors: Fawzy Nabiyl Ahmad , Awaluddin Nurhikma , Muntasir,
Published: March 2024

Squid cartilage (Loligo sp.) is known to contain chitosan compounds that have antibacterial activity. This study aims to formulate chitosan from squid cartilage (Loligo sp.) in the form of handwash preparations with concentrations of 0.1%, 0.2%, and 0.3% which are physically and chemically stable, and see the optimum concentration in inhibiting bacterial growth.  The method used is laboratory experiments through three stages of extraction, namely deproteination, demineralization, and deacetylation as well as physical quality tests and ability tests before and after cycling tests which include organoleptic tests, homogeneity tests, pH tests, viscosity tests, foam height tests and antibacterial activity tests against Staphylococcus aureus and Escherichia coli bacteria by the method of sumuran. The results obtained based on the ANOVA test on Staphylococcus aureus bacteria are 0.000 and on Escherichia coli bacteria are 0.000.  Chitosan from squid cartilage (Loligo sp.) can be formulated in the form of a handwash preparation and the most effective concentration in inhibiting Staphylococcus aureus and Escherichia coli is a concentration of 0.3%.
ANALYSIS OF FACTORS AFFECTING THE INCOME OF FISH TRADERS
Authors: Suseno. D.A.N.  , Supriyadi. B  , Nugraha. J.P.  , Rahardjo. S  , Suseno. D.N
Published: March 2024

Research on factors that influence fish traders' income is still limited regarding business experience and business analysis carried out by fish traders. The importance of analyzing the factors that influence fish traders' income cannot be underestimated in the context of fisheries economics in increasing the per capita income of fish traders in Indonesia. Therefore, this research aims to analyze which factors have the most influence on fish traders' income, with the variables Capital (x1), Trading Time (x2), and Selling Time Allocation (x3). Determining respondents in the study used a purposive sampling method, namely fish traders in the Sedati District area, Sidoarjo. The number of respondents will be determined using the Slovin method, and the data obtained will be analyzed using the multiple linear analysis method. The data obtained were analyzed using the SPSS application and showed that the capital variable (x1) was proven to have a positive influence on fish income in the Sedati District area, with a t table value of 2,233 > 1.697 t count and a sig value = 0.033 < 0.05 so that Ha was accepted. The conclusion of this research is that the capital variable (x1) has a real influence on the income of fish earners in Sedati District. This research is useful for the community, especially fish traders, that sufficient capital is the most influential thing in obtaining income, because the greater the capital used, the greater the income obtained.
FINANCIAL AND NON-FINANCIAL FACTORS AFFECTING SUKUK IJARAH RATINGS
Authors: Maulidina Rizky Awaliyah , Bustami Abiyajid , Maulana Indra
Published: March 2024

This study aims to analyse what affects the rating of sukuk ijarah as seen from financial and non-financial factors. This research is quantitative research using the SPSS application. the sample of this research is companies that issue sukuk ijarah in the 2014-2018 period and are rated by PEFINDO. Indicators of financial factor variables are measured by CR (Current Ratio), ROA (Return on Asset), TATO (Total Asset Turn Over) and DER (Debt to Equity Ratio). While the non-financial factors used are the age of sukuk. The results of this research are financial ratios that affect sukuk ratings are CR and ROA. Where seen from the partial test these two ratios are significant. Meanwhile, if examined simultaneously CR, ROA, TATO, DER and sukuk age on sukuk ratings, the results have a significant effect. This means that all financial ratios and sukuk age simultaneously affect the ijarah sukuk rating.
AREAL AND PRODUCTION OF PALM OIL TREES
Authors: Setiowati Yuli , Jufri Fikri , Arahman  , Asman  , Huda Ismul
Published: March 2024

Palm oil is one of the plantation products that has a significant impact on the Indonesian economy. Indonesia, being one of the major palm oil exporters in the world, has successfully reduced poverty and unemployment rates by expanding oil palm plantation areas. This research aims to explore the relationship between the extent of oil palm plantation land and the annual production of palm oil in Paser Regency. The research method employed for this study is quantitative, involving the collection of data on the amount of palm oil plantation land from 2018 to 2022, along with the annual palm oil production figures in Paser Regency. The gathered data will be examined using correlation analysis, utilizing IBM SPSS 25 as the tool for conducting the correlation analysis. The researcher found that there is no significant correlation between the extent of oil palm plantation land and annual palm oil production. Additionally, the researcher discovered other variables that correlate with the annual volume of palm oil production, which were not considered in this study. The variables identified by the researcher as influencing production volume after conducting this study include soil conditions, fertilizers, seedlings, human resources, and the age of oil palm trees. This research provides insights to readers, stakeholders, and other researchers regarding factors correlated with the annual volume of palm oil production. These findings can serve as a solid foundation for business decision-making and as reference material for future research.
THE RELATIONSHIP OF GADGET ADDICTION ON MENTAL HEALTH IN MEDICAL STUDENTS
Authors: Anissa Mutiara , Maska Hadid Pratama , Ariwibawa Tangguh , Abdullah Dessy
Published: March 2024

Smartphone, is a term to distinguish advanced feature phones from basic feature phones. Excessive smartphone use or addiction can lead to negative health consequences such as neck pain, accidents, anxiety, depression, and sleep disorders. This study aims to determine how the influence of gadget use addiction on mental health in medical students. Method used (narrative review/systematic review with PRISMA 2020). Research was collected through searches on Google Scholar from 2019 to 2023, Ebscho from 2019 to 2023 with full text limits and PubMed from 2019 to 2023. The keyword searches used are smartphone addiction, mental health, and medical student. 210 results were found from Google Scholar, 15 results were found on Ebscho, 31 results were found on PubMed, and 21 studies were included in the study. Results of the 256 journals netted, there are 21 journals that match the category of literature review titles. There is a significant relationship between gadget addiction to mental health in medical students, especially in women.
HEIDEGGER: UNDERSTANDING AND INTERPRETATION AS DAS SEIN EXISTENTIAL (Analysis of Verses of God's Appreciation on Humans in Tafsir Ibn Katsīr)
Authors: A.F. Udin  , S. Bahri
Published: March 2024

Recently, hermeneutics has become a study that has attracted the attention of observers of al-Qur’an and Tafsir. One of its studies is Heidegger's hermeneutics. In brief, there are four main things in Gadamer's hermeneutics, namely facticity, understanding, ontological-existential relations, and time. This literature research aims to discuss Ibn Katsīr's interpretation which is analyzed from Heidegger's hermeneutics. The results of the research show that Ibnu Katsīr has been influenced by socio-cultural conditions or what is called facticity. Second, there is pre-understanding, and third, the openness of the interpreter in the context of further interpretation. Implicitly, Ibn Katsīr was becoming das sein existing in the understanding itself.
ECOTOURISM IN SIMATUPANG VILLAGE: TURNING CHALLENGES INTO OPPORTUNITIES
Authors: Tambunan Ellyta , Masatip Anwari
Published: March 2024

Simatupang Village is a village located in Muara Sub-district, North Tapanuli Regency.. Simatupang Village has great potential for the application of the ecotourism concept because of its abundant natural resources and strong culture, but it is not well managed. The purpose of this research is to find out the concept of ecotourism in Simatupang Village and to find out the development of sustainable tourism in Simatupang Village. The research method used is a qualitative research method with a descriptive approach. The data collection techniques used were observation, interviews, and literature study, and the data analysis technique used was descriptive qualitative analysis. The concept of ecotourism in Simatupang Village is an ecotourism concept based on nature conservation and utilizing the environment and culture inherent in the community as a tourist destination that can increase income and prosper the community.
Digital Marketing Strategy for Mangrove Ecotourism Towards Sustainable Development Goals (SDG) 8.3 (Case Study: Rawa Aopa Watumohai National Park, Southeast Sulawesi)
Authors: Salam Salmiya Ismail , Lubis Ratna Lindawati
Published: March 2024

The purpose of this research is to analyze the external and internal environment, including opportunities, challenges, strengths, and weaknesses, regarding the Digital Marketing Strategy for Mangrove Ecotourism towards SDG 8.3 at Rawa Aopa Watumohai National Park. This research method utilizes a qualitative approach with SWOT analysis. Findings reveal that the Park supports various training and capacity-building activities for local entrepreneurs around the Park, reflecting the local community's enthusiasm for entrepreneurship, thus establishing a connection between SDG 8.3 and the Park. Weaknesses include the need for improvement in the quantity of tourism facilities, transportation, public infrastructure, and internet connectivity. Opportunities arise from leveraging social media for optimal promotion of tourism locations to attract tourists. Threats stem from competition with similar tourist destinations, potentially reducing visitor numbers. Additionally, climate change and threats to species diversity in the park necessitate better management planning.
Knowledge of Diabetes among Diabetic Patients Attending at Tertiary Level Hospital
Authors: Shrestha Krishna Devi , KC Takma , Ghimire Rachana
Published: March 2024

Background: The prevalence of Diabetes Mellitus is growing at an alarming rate across the globe.  Obtaining knowledge regarding diabetes is the initial step in formulating a prevention program for  diabetes which can assist in the early detection of the disease and reduce complications. Hence, the  objective of this study was to assess the level of knowledge regarding aspects of diabetes among  diabetic patients. 

Methods: The study was conducted using a descriptive cross-sectional research design at Tribhuvan  University Teaching Hospital (TUTH). A purposive sampling technique was adopted. Data was  collected in 3 months from December 2017 to March 2018 by using a structured questionnaire through  interview method among 422 respondents fulfilling the inclusion criteria attending in medical OPD.  Analysis was done by descriptive and inferential statistics. 

Results: The study findings revealed that nearly half of the respondents (43.4%) had moderately  adequate knowledge, 36.5% of respondents had adequate and 20.1% had inadequate knowledge on  diabetes mellitus. The overall knowledge score was 65.37±SD17.58. Knowledge scores in different  aspects of diabetes revealed that respondents had adequate knowledge on diet (79.3%), medicine  (78.4%), complications with diabetes mellitus (75.8%) and moderately adequate knowledge was  found on the meaning of diabetes (62.5%), exercise (67%), diabetic foot care (52.6%), blood glucose  monitoring (53.3%) and follow up visit (75.8%). Diabetic patient’s age (0.026), sex (0.012), education  (<0.001), occupation (<0.001), area of residence (0.005) and attended in diabetic counseling (<0.001)  were significantly associated with level of knowledge. 

Conclusion: It is concluded that less than half of the diabetes patients have adequate knowledge  on diabetes mellitus and it is associated with age, sex, education, occupation, area of residence and  attended diabetic counseling.
Pactos en previsión de ruptura familiar: una comparación entre la jurisprudencia italiana y la española, en la esperanza de que la primera aprenda de la segunda
Authors: Barba Vincenzo
Published: March 2024

El artículo propone un análisis comparativo de la jurisprudencia española e italiana sobre los pactos en previsión de ruptura familiar, para mostrar que, a pesar de la similitud de los dos ordenamientos jurídicos, la jurisprudencia ha llegado a soluciones diametralmente opuestas: la jurisprudencia italiana negando la validez de cualquier pacto prematrimonial e incluso de los pactos celebrados después de la separación y en previsión del divorcio; la jurisprudencia española admitiendo la plena validez de estos acuerdos, como expresión de la autonomía de los cónyuges. Considerando que los pactos en previsión de ruptura familiar deben considerarse válidos y esperando una regulación uniforme del derecho europeo, que sería deseable, el ensayo propone algunas soluciones que deberían tenerse en cuenta en una posible reforma.
Maternidad subrogada
Authors: Bercovitz Rodriguez-Cano Rodrigo
Published: February 2024

La Sala de lo Civil del TS, en su Sentencia de 31 de marzo de 2022, reitera la contravención del orden público español del reconocimiento de la maternidad subrogada como título de atribución de la maternidad del comitente de un contrato de gestación subrogada. El autor elogia la toma de postura del TS, en línea con el CEPDHLF y con la jurisprudencia del TEDH, frente a los postulados defendidos, v.gr., por la DGSJyFP, y afirma que los contratos de gestación por sustitución entrañan una explotación de la mujer gestante y un daño a los intereses superiores del menor.
Crónica jurisprudencial (IV): agosto – diciembre 2022
Authors: García Vicente José-Ramón
Published: February 2024

Esta crónica recoge un periodo especialmente fructífero de la sala primera del Tribunal Supremo en materias bien dispares entre sí. En particular, se da cuenta de las sentencias de Pleno 579/2022, de 26 de julio (Rafael Sarazá Jimena), sobre los principios de justicia rogada y congruencia en los pleitos de consumo; 747/2022, de 14 de octubre (Antonio García Martínez), sobre el control de los comentarios en Facebook; y la senten-cia 771/2022, de 10 de noviembre (José Luis Seoane Spiegelberg) relativa a desahucio por precario y alegación de la Ley 1/2013 por el precarista.
El control judicial de cláusulas abusivas en la jurisprudencia del Tribunal Constitucional a la luz de la jurisprudencia del TJUE
Authors: Martínez Escribano Celia
Published: February 2024

A partir de la STC 31/2019, de 28 de febrero, se ha ido consolidando una jurisprudencia constitucional que aprecia la vulneración del derecho a la tutela judicial efectiva cuando el juez, en un procedimiento de ejecución (habitualmente ejecuciones hipotecarias) se niega a realizar el control de cláusulas abusivas solicitado por una de las partes del proceso -el ejecutado que reúne la condición de consumidor- una vez que ha transcurrido el plazo para formular oposición a la ejecución. Tal vulneración se produciría porque el juez en este caso estaría inaplicando el derecho de la Unión Europea y, particularmente, lo establecido en la STJUE Banco Primus. Más recientemente, se ha dictado un nuevo pronunciamiento del TJUE que incide con mayor detalle sobre estas cuestiones y que lleva a plantear si esta jurisprudencia constitucional merece ser revisada en algún sentido. A esta cuestión se dedica este estudio.
«LARGA HE SIDO PERO NO CUANTO DESEO»: LAS MUJERES COMO REDACTORAS DE CARTAS EN LA CULTURA ESCRITA DE LA EDAD MODERNA
Authors:   GRISO – Universidad de Navarra, TABERNERO SALA CRISTINA
Published: February 2024

This work analyzes the female linguistic behaviour in 17th and 18th century love letters signed by women. These texts are contrasted with others from the same period which were written by men and which are part of the same discursive tradition. In order to achieve reliable conclusions, we contextualize the female figure as the writer of letters ―especially love epistles―, and we locate this discursive mold within the rethorics field. Thus, the preferred features that divide men’s and women’s language are singled out, according to the different parts of the discourse (heading and salutation, exordium, peroratio and farewell). Furthermore, the influence of sociocultural and discursive covariance factors ―which converge in the distribution of the social role traditionally assigned to men and women― is established in a different approach of the same discursive manifestation, which shows no significant variations in the chronological axis of both of the considered centuries.
Analisis Cita Rasa Kopi di Tilik Kopi Kota Padang
Authors: Taufik Rahman  , Retnaningtyas Susanti  , Nidia Wulansari  , Hendri Azwar
Published: February 2024

This research was motivated by customer reviews regarding the taste of coffee in Padang City Coffee. This research is classified as qualitative research with the method used being descriptive. The variables used in this research are coffee and taste. The research sample was 5 people, data was collected by distributing observations and interviews. The results of this research show that the aroma of the product presented is good with the criteria of a typical coffee aroma without the presence of the aroma of other ingredients such as chemicals. The acidity of the product presented is quite good with the typical criteria for coffee acid which has a pH of 4.85 to 5.10. The level of balance of taste of the product served is good because the coffee served has a taste that is formed due to the right mixture of ingredients. The level of viscosity of the product served is good by paying attention to the amount of ground coffee that will be processed with the water used using a dose of 1:2 with water. The bitter taste of the product served is very good because the bitterness produced is just right due to correct coffee processing, without any other causes such as bad coffee powder. The sweet taste of the product served is quite good according to consumer tastes. From all the aspects considered in this research, in general, espresso is better than Americano because espresso is the basis for making Americano itself.
Frecuencia de síntomas relacionados con depresión, ansiedad y estrés en adultos mayores que presentaron enfermedad por COVID-19 en una Unidad de Medicina Familiar de Mexicali, Baja California. México
Authors: Estrada Gómez José Roberto , Ortega Vélez Guadalupe , Haro Acosta María Elena , Ayala Figueroa Rafael Iván
Published: March 2024

Objetivo: Determinar la frecuencia de síntomas relacionados con depresión, ansiedad y estrés en los adultos mayores que presentaron enfermedad por COVID-19. Método: Estudio transversal en adultos mayores que hubieran presentado enfermedad por COVID-19 adscritos a la Unidad de Medicina Familiar No16 de la ciudad de Mexicali, Baja California del Instituto Mexicano del Seguro Social. Se incluyeron a 60 pacientes mediante un muestreo no probabilístico por cuotas en el período de enero a marzo del 2022. Fue aplicada la escala DASS-21 para evaluar los estados de depresión, ansiedad y estrés. Resultados: Predominó el sexo femenino con el 55%, el promedio de edad entre 60 a 65 años. La frecuencia de depresión fue de 5.71%, ansiedad 10% y estrés 9.76 %. Conclusiones: Predominaron niveles bajos según el test DASS-21. Los problemas emocionales son frecuentes en los adultos mayores que padecen COVID-19 por lo que se deben detectar tempranamente.
Learning from medical and surgical errors: a new global insight for patients safety.
Authors: De Simone Belinda
Published: February 2024

Medical errors are a pressing global public health challenge today, causing a 10% annual incidence of adverse events, increased patient mortality, and incredibly high costs for healthcare systems worldwide. The Journal of Medical and Surgical Errors’ mission is to recognize, report, and discuss errors through a multidisciplinary approach in order to both minimize error recurrence and enhance patient safety. By investigating the factors influencing error recurrences and effective preventive strategies, we aim to contribute to the reduction of preventable medical errors. Our role extends beyond mere publications; it is a commitment to transformative change in the approach to errors in healthcare. We invite researchers to contribute to building a comprehensive body of knowledge that advances our understanding of errors in medicine and surgery. Together, let us shape a future where transparency, learning, and patient safety are paramount in medical practice.
Analysis of Fire Alarm Performance Effectiveness in MV. Rajakarta
Authors: Sinaga Meidiana Putri , Wiweko Albert , Siregar Muhammad Sapril
Published: March 2024

Fires on ships pose a high risk due to limited access to help from land and firefighting equipment. To minimize these risks, it's important to maximize the effectiveness of the fire alarm system. This can be done by quickly detecting any smoke or fire using the alarm system and taking immediate action before the fire spreads. A qualitative descriptive method was used in this research to investigate the decline in the working function of fire alarms. The research focused on the problems with fire alarm smoke detectors and the correct maintenance methods. The findings of the research indicate that the lack of maintenance and repair of the fire alarm system are the main factors that cause the decline in the capability of fire alarm sensors. To ensure that the fire alarm system works properly, it should be routinely and periodically maintained. This will help to prevent any potential issues and ensure that the alarm system is always functioning at its best.
Crafting Strategies for Ambience Economy in Rural Revitalization: A Scholarly Endeavor
Authors:   School of Art and Design, Sanming University, Sanming, Fujian Province, China, 365004,1912896911@qq.com, LI Zhensheng
Published: February 2024

Amidst the relentless march of urbanization, rural revitalization has emerged as a pivotal agenda in China's socio-economic landscape. The ambiance economy, a paradigm that prioritizes emotional engagement and experiential value, presents a latent yet formidable potential for invigorating rural economies. This paper endeavors to delineate strategies for harnessing the ambiance economy to foster a distinctive rural atmosphere, thereby catalyzing economic growth in rural regions. Utilizing a comprehensive literature review and in-depth case studies, the research articulates a novel array of approaches that align with contemporary demands and chart a course for the sustainable progression of rural revitalization.
A Review of the Research Process of Building a New Public Security College Think Tank
Authors: HU Kaifeng , XUE Peng , WANG Zhelin
Published: February 2024

Think tanks in public security academies are not only one of the important components to ensure scientific decision-making in public security, but also an important initiative to deepen public security reform. Domestic scholars have interpreted the meaning, construction and development paths of public security academy think tanks from different perspectives, with domestic studies focusing on the internal integration of public security academy think tanks with the Ministry of Public Security, while foreign studies focus more on the unofficiality and independence of think tanks. Examining the process of research on the construction of new public security academy think tanks in domestic and foreign academia helps to grasp the new areas and trends of their research at the theoretical level and offer suggestions to promote the development of new public security academy think tanks.
ADVANCING ENVIRONMENTAL SUSTAINABILITY: ENHANCED PHO- TOCATALYTIC DEGRADATION OF CEFOPERAZONE USING ZnO AND H2O2 UNDER DIFFERENT RADIATION SOURCES
Authors: Bilić Andrijana , Savanović Maria M. , Armaković Stevan , Pelemiš Svetlana , Armaković Sanja J.
Published: February 2024

Cefoperazone is a widely utilized antibiotic from the cephalosporins group to treat bacterial infections. Nevertheless, due to its extensive use as a β-lactam antibiotic, it has been found to accumulate in aquatic environments, leading to notable adverse effects on flora and fauna. Consequently, there arises a necessity for its removal from the environment. The aim of this work was to investigate the efficiency of photocatalytic degradation of cefoperazone by ZnO and H2O2 using different types of radiation (simulated solar (SS), UV-LED, and UV). The applied nanomaterial in the presence of H2O2 showed significant effi- ciency in removing cefoperazone compared to direct photolysis. In the first 20 min of irradiation, 49.0% and 59.4% of cefoperazone were degraded when SS and UV-LED were used, respectively, while cefopera- zone was completely degraded under UV irradiation. The reaction rate constant indicates that the degrada- tion of cefoperazone is pseudo-first order..
Adapting to ever-changing conditions
Authors: Pelet Serge
Published: February 2024

Experiments involving periodic stimuli shed light on the interplay between hyper-osmotic stress and glucose starvation in yeast cells.
Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment
Authors: Mukherjee Ananda Kishore , Dutta Subhajit , Singh Ankita , Sharma Shalu , Roy Shuvra Shekhar , Sengupta Antara , Chatterjee Megha , Vinayagamurthy Soujanya , Bagri Sulochana , Khanna Divya , Verma Meenakshi , Soni Dristhi , Budharaja Anshul , Bhisade Sagar Kailasrao , Vivekanand  , Perwez Ahmad , George Nija , Faruq Mohammed , Gupta Ishaan , Sabarinathan Radhakrishnan , Chowdhury Shantanu
Published: March 2024

Telomeres are crucial for cancer progression. Immune signalling in the tumour microenvironment has been shown to be very important in cancer prognosis. However, the mechanisms by which telomeres might affect tumour immune response remain poorly understood. Here, we observed that interleukin-1 signalling is telomere-length dependent in cancer cells. Mechanistically, non-telomeric TRF2 (Telomeric Repeat binding Factor 2) binding at the IL-1-receptor type-1 (IL1R1) promoter was found to be affected by telomere length. Enhanced TRF2 binding at the
IL1R1
promoter in cells with short telomeres directly recruited the histone-acetyl-transferase (HAT) p300, and consequent H3K27 acetylation activated IL1R1. This altered NF-kappa B signalling and affected downstream cytokines like
IL6, IL8
and
TNF
. Further,
IL1R1
expression was telomere-sensitive in triple-negative breast cancer (TNBC) clinical samples. Infiltration of tumour-associated macrophages (TAM) was also sensitive to the length of tumour cell telomeres and highly correlated with
IL1R1
expression. The use of both IL1 Receptor antagonist (IL1RA) and
IL1R1
targeting ligands could abrogate M2 macrophage infiltration in TNBC tumour organoids. In summary, using TNBC cancer tissue (>90 patients), tumour-derived organoids, cancer cells and xenograft tumours with either long or short telomeres, we uncovered a heretofore undeciphered function of telomeres in modulating IL1 signalling and tumour immunity.
Integrating hybrid transfer learning with attention-enhanced deep learning models to improve breast cancer diagnosis
Authors: Jakkaladiki Sudha Prathyusha , Maly Filip
Published: February 2024

Cancer, with its high fatality rate, instills fear in countless individuals worldwide. However, effective diagnosis and treatment can often lead to a successful cure. Computer-assisted diagnostics, especially in the context of deep learning, have become prominent methods for primary screening of various diseases, including cancer. Deep learning, an artificial intelligence technique that enables computers to reason like humans, has recently gained significant attention. This study focuses on training a deep neural network to predict breast cancer. With the advancements in medical imaging technologies such as X-ray, magnetic resonance imaging (MRI), and computed tomography (CT) scans, deep learning has become essential in analyzing and managing extensive image datasets. The objective of this research is to propose a deep-learning model for the identification and categorization of breast tumors. The system’s performance was evaluated using the breast cancer identification (BreakHis) classification datasets from the Kaggle repository and the Wisconsin Breast Cancer Dataset (WBC) from the UCI repository. The study’s findings demonstrated an impressive accuracy rate of 100%, surpassing other state-of-the-art approaches. The suggested model was thoroughly evaluated using F1-score, recall, precision, and accuracy metrics on the WBC dataset. Training, validation, and testing were conducted using pre-processed datasets, leading to remarkable results of 99.8% recall rate, 99.06% F1-score, and 100% accuracy rate on the BreakHis dataset. Similarly, on the WBC dataset, the model achieved a 99% accuracy rate, a 98.7% recall rate, and a 99.03% F1-score. These outcomes highlight the potential of deep learning models in accurately diagnosing breast cancer. Based on our research, it is evident that the proposed system outperforms existing approaches in this field.
Enhancing software defect prediction: a framework with improved feature selection and ensemble machine learning
Authors: Ali Misbah , Mazhar Tehseen , Al-Rasheed Amal , Shahzad Tariq , Yasin Ghadi Yazeed , Amir Khan Muhammad
Published: February 2024

Effective software defect prediction is a crucial aspect of software quality assurance, enabling the identification of defective modules before the testing phase. This study aims to propose a comprehensive five-stage framework for software defect prediction, addressing the current challenges in the field. The first stage involves selecting a cleaned version of NASA’s defect datasets, including CM1, JM1, MC2, MW1, PC1, PC3, and PC4, ensuring the data’s integrity. In the second stage, a feature selection technique based on the genetic algorithm is applied to identify the optimal subset of features. In the third stage, three heterogeneous binary classifiers, namely random forest, support vector machine, and naïve Bayes, are implemented as base classifiers. Through iterative tuning, the classifiers are optimized to achieve the highest level of accuracy individually. In the fourth stage, an ensemble machine-learning technique known as voting is applied as a master classifier, leveraging the collective decision-making power of the base classifiers. The final stage evaluates the performance of the proposed framework using five widely recognized performance evaluation measures: precision, recall, accuracy, F-measure, and area under the curve. Experimental results demonstrate that the proposed framework outperforms state-of-the-art ensemble and base classifiers employed in software defect prediction and achieves a maximum accuracy of 95.1%, showing its effectiveness in accurately identifying software defects. The framework also evaluates its efficiency by calculating execution times. Notably, it exhibits enhanced efficiency, significantly reducing the execution times during the training and testing phases by an average of 51.52% and 52.31%, respectively. This reduction contributes to a more computationally economical solution for accurate software defect prediction.
Increased MCHC*RDW-SD interaction values: indicators of neurological impairment in lead-poisoned children
Authors: Ying Qingji , Ye Mengsi , Zhang Tingting , Xia Zhaobo , Chen Huale
Published: February 2024

Background

The neurotoxic effects of lead in children can have long-lasting and profound impacts on the developing nervous system. This study aimed to identify a reliable and easily accessible biomarker to monitor neurological impairment in lead-poisoned children.

Methods

We analyzed hematological data from 356 lead-poisoned children, comparing them with age and gender-matched healthy controls. Multivariate logistic regression and receiver operating characteristic (ROC) analysis were employed to identify and evaluate potential biomarkers for neurological damage.

Results

Significant changes in erythrocyte parameters were observed in lead-poisoned children. Upon further analysis, increased mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width-standard deviation (RDW-SD) interaction values were found to be significantly associated with neurological impairment. The MCHC*RDW-SD interaction model demonstrated an AUC of 0.76, indicating its effectiveness in reflecting neurological damage. Additionally, the MCHC*RDW-SD Interaction value showed weak or no correlation with other erythrocyte parameters, suggesting its independence as an indicator.

Conclusion

Our findings propose the increased MCHC*RDW-SD interaction value as a robust and independent biomarker for detecting neurological impairment in lead-poisoned children. This underscores the potential of utilizing specific erythrocyte parameters for screening the neurotoxic effects of lead exposure in pediatric populations.
Bimetallic nanoparticles and biochar produced by Adansonia Digitata shell and their effect against tomato pathogenic fungi
Authors: Aldahasi Reham M. , Shami Ashwag , Mohammed Afrah E.
Published: March 2024

Adansonia digitata L. is a royal tree that is highly valued in Africa for its medicinal and nutritional properties. The objective of this study was to use its fruit shell extract to develop new, powerful mono and bimetallic nanoparticles (NPs) and biochar (BC) using an eco-friendly approach. Silver (Ag), iron oxide (FeO), the bimetallic Ag-FeO NPs, as well as (BC) were fabricated by A. digitata fruit shell extract through a reduction process and biomass pyrolysis, respectively, and their activity against tomato pathogenic fungi Alternaria sp., Sclerotinia sclerotiorum, Fusarium equiseti, and Fusarium venenatum were detected by agar dilution method. The Ag, FeO, Ag-FeONPs, and BC were characterized using a range of powerful analytical techniques such as ultraviolet–visible (UV–Vis) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier Transform-Infra Red (FT-IR), dynamic light scatter (DLS), and zeta potential analysis. The fabricated Ag, FeO and Ag-FeO NPs have demonstrated a remarkable level of effectiveness in combating fungal strains. UV–Vis spectra ofAg, FeO, Ag-FeONPs, and BC show broad exhibits peaks at 338, 352, 418, and 480 nm, respectively. The monometallic, bimetallic NPs, and biochar have indicated the presence in various forms mostly in Spherical-shaped. Their size varied from 102.3 to 183.5 nm and the corresponding FTIR spectra suggested that the specific organic functional groups from the plant extract played a significant role in the bio-reduction process. Ag and Ag-FeO NPs exhibited excellent antifungal activity against pathogenic fungi Alternaria sp., S. sclerotiorum, F. equiseti, and F. venenatum. The current study could be a significant achievement in the field of antifungal agents since has the potential to develop new approaches for treating fungal infections.