bluuebunny/crossref_metadata_2025 huggingface dataset:
Comunicação breve: Inibição in vitro de esterases de cascudo-marrom (Pterygoplichthys anisitsi) de diferentes tamanhos pelo inseticida organofosforado clorpirifos: uma atividade prática de ecotoxicologia na Pós-Graduação em Biodiversidade.
Authors: Alves de Almeida Eduardo , Lilian Nogueira
Published: July 2023

Inseticidas organofosforados, como o clorpirifos, exercem sua toxicidade pela inibição de enzimas esterases, tais como a acetilcolinesterase (AChE) e carboxilesterase (CbE) em insetos e outros animais. Por isso, a avaliação da atividade destas enzimas é amplamente utilizada como biomarcadora da exposição de animais a estes tipos de compostos, em estudos de monitoramento ambiental. No presente estudo, a compreensão desses efeitos foi transmitida a alunos do Programa de Pós-Graduação em Biodiversidade da UNESP, por meio de experimento prático realizado na disciplina de Ecotoxicologia. Esses conceitos foram abordados por meio de uma avaliação comparativa entre os efeitos de inibição in vitro da AChE e da CbE pelo inseticida clorpirifos, em cascudos-marrom (Pterygoplichthys anisitsi) de três faixas diferentes de tamanho (10-14, 15-19 e 20-24 cm). Os resultados indicaram discrepâncias entre os valores de atividade enzimáticas entre os diferentes grupos de peixes. Ainda, animais menores foram mais sensíveis à inibição da AChE pelo clorpirifos, enquanto que os animais maiores foram mais sensíveis à inibição da CbE. Além de contribuir para o aprendizado dos alunos, o estudo trouxe dados inéditos sobre a sensibilidade de esterases de cascudos-marrom ao clorpirifos.
Uso da semaglutida para redução do peso em pacientes obesos não diabéticos e efeitos adversos associados
Authors: Arruda Tiê Barbosa , Lopes Júnior José Ademir Távora , Albuquerque Thamires Menezes de , Coelho Rafael Vilanova , Melo Antônio Alcides Janja , Bachur Tatiana Paschoalette Rodrigues
Published: July 2023

A obesidade é considerada uma pandemia global, afetando países de todos os níveis de desenvolvimento e todas as faixas etárias. No contexto brasileiro, a obesidade também representa um desafio significativo para a saúde pública. É nesse cenário que a semaglutida começa a se popularizar como uma opção para o tratamento da obesidade. Dessa forma, o objetivo deste trabalho foi realizar uma revisão bibliográfica que coloque em relevo os possíveis efeitos adversos do uso de semaglutida para emagrecimento em pacientes obesos e sem o diagnóstico de diabetes. Para tal, foi conduzida uma pesquisa nas bases de dados MEDLINE, EMBASE e LILACS, tendo sido utilizados oito artigos selecionados a partir de critérios previamente definidos. Foi verificado que o risco de desenvolver alterações gastrointestinais foi maior com o uso de semaglutida, embora a duração destes efeitos adversos seja curta, transitória e resolutiva sem interrupção do tratamento. Embora esses efeitos sejam em sua maioria leves a moderados e de curta duração, eles podem levar à interrupção temporária do tratamento ou à redução da dose. Além disso, foram relatados casos raros, mas graves, de distúrbios hepatobiliares, como pancreatite aguda e colelitíase. Portanto, para a prescrição da semaglutida para os pacientes com o objetivo de perda de peso, é fundamental a avaliação cuidadosa dos riscos e benefícios individuais, bem como a monitorização regular dos pacientes para a detecção de efeitos adversos gastrointestinais e hepatobiliares.
Reflections of The Evolution of The Pole Used in Pole Vaulting on The Olympic Games Podium
Authors: SATILMIŞ Nuray
Published: July 2023

Pole vault is one of the disciplines in athletism. The material used in manufacturing of pole has been changing from time to time. Material of traininand competition in sports is one of the factors that determine performance. In this study, it is aimed to investigate reflection of pole evolution to olimpic marks on pole vault. The data of this study consist of highest jumping heihts and average values of these marks for gold, silver and bronze medals in pole vault branch of Olimpic Games (n=28) for the games between 1896-2016. The data are obtained from WA official internet site. It was seen at the end of study that allowing the develop maretial technology in poles resulted in obtaining higher performance in pole vault branch.
Implementation of a “seamless” model of providing specialized medical care to patients with heart failure
Authors: Kobalava Zhanna D. , Tolkacheva Veronica V. , Vatsik-Gorodetskaya Maria V. , Cabello-Montoya Flora E. , Nazarov Ivan S. , Galochkin Svyatoslav A.
Published: July 2023

Heart failure (HF) is a widespread disease and tends to increase. Despite the possibilities of modern therapy, the prognosis of patients with HF remains unfavorable. Foreign experience shows that the creation of specialized heart failure clinics improves the quality of care for patients with HF, reduces the frequency of repeated hospitalizations and death of patients. The Russian Federation has gained experience in creating such clinics, in particular, in Nizhny Novgorod, Ufa, St. Petersburg and a number of other cities. The article describes the organization of the work of the Center for HF on the basis of a multidisciplinary hospital in Moscow in period 01.11.2020-01.12.2022. The database included 2,400 patients hospitalized due to acute decompensation of chronic HF (ADCHF). The leading triggers of ADCHF in the studied patient population were an episode of atrial fibrillation/flutter (37 %), low adherence to treatment (25 %) and uncontrolled hypertension (17 %), exacerbation of concomitant diseases (11 %), infection (4 %). In 6 % of patients, the leading trigger could not be identified. The hospital stage included 950 (39.5 %) patients who, in the first 24 hours from the moment of hospitalization, underwent standard physical, laboratory and instrumental examination, including lung ultrasound, NT-proBNP, liver fibroelastometry, VEXUS protocol study, bioimpedance analysis of body composition, of which 496 (20.5 %) people passed the same studies at discharge. In the structure of patients hospitalized with ADCHF who were included in the hospital follow-up stage (n=950), patients with preserved (HFpEF) 42.5 % (n=404) and reduced ejection fraction (HFrEF) prevailed 36 % (n=342), patients with a mildly reduced (HFmrEF) ejection fraction were found in 21.5 %. 1,552 (64.5 %) patients refused additional studies and visits to the CH center, but agreed to outpatient follow-up in the form of telephone contacts. In 370 (15.4 %) patients, contact was lost after discharge. 240 (10 %) patients actively visit the HF center with a comprehensive assessment of congestion and correction of therapy at each visit. Conclusion. There are two stages in the treatment of patients with chronic HF. The first stage is hospital, the second one is outpatient. It is important not to make omissions in the prescribed drug therapy, which can lead to a fatal outcome. To this end, it is necessary to introduce a “seamless” model of medical care for patients with chronic HF, when the patient comes under the supervision of a multidisciplinary team that carries out timely monitoring.
Arterial hypertension in young adults
Authors: Bazdyreva Elena I. , Shavarova Elena K. , Ezhova Nadezhda E. , Kirpichnikova Ekaterina I. , Kobalava Zhanna D.
Published: July 2023

Arterial hypertension (AH) is associated with the development of pathological changes in target organs, which leads to an increase in morbidity and mortality. The aim of the review was to discuss the peculiarity of AH in young people, in particular risk factors for developing AH, associations between the risk of cardiovascular events and elevated blood pressure in young adults, blood pressure phenotypes in young people, the role of traditional cardiovascular diseases risk factors in young people with AH, features of target organ damages in young people with AH and optimal blood pressure for target organ protection. Threshold values of blood pressure, from which the cycle of pathological changes starts, have not been finally determined, however, it is likely that they are significantly lower than the blood pressure values that are currently used to diagnose AH n in Europe and Russia. Reclassification of AH using more strict criteria in the United States resulted in an increase in the prevalence of AH from 29 % to 43 %, and affected mainly young people. Obesity, increased daily sodium excretion, increased consumption of meat products, dyslipidemia, hyperinsulinemia, hyperuricemia, high levels of depression and low social status are among the potential risk factors for developing AH at a young age, while a low-salt diet, eating a large amount of plant foods, high in carotenoids and folate, and a high level of physical activity may have a preventive effect on the development of AH. The results of recent studies indicate a high prevalence of AH, including masked, in young people, which often remains underestimated in real clinical practice. The strategy for the treatment of AH in young patients has not been determined, which is associated with an insufficient evidence base. Studies are needed to identify additional arguments for initiating or withholding antihypertensive therapy in this population, including the study of early signs of hypertension-associated target organ damage. Conclusion. The results of recent studies indicate a high prevalence of hypertension, including masked, in young people, which often remains underestimated in real clinical practice. Further research is required to identify additional arguments for initiating or withholding antihypertensive therapy in this population, including the study of early signs of hypertension-associated target organ damage.
Respiratory system functional state in patients after the left ventricle geometric reconstruction followed by conventional respiratory rehabilitation
Authors: Lobacheva Galina V. , Alshibaya Mikhail M. , Mamalyga Maksim L. , Zatenko Mark A. , Danilov Sergey A. , Arzumanyan Milena A.
Published: July 2023

Relevance. Post-infarction left ventricular aneurysm (PILVA) is the most severe complication of myocardial infarction in patients with ischemic heart disease. Systemic hemodynamic disorders in PILVA can lead to respiratory dysfunction before surgery and worsen cardiorespiratory failure in the postoperative period. Despite modern opportunities for early diagnosis and treatment of respiratory dysfunction, effective methods of postoperative respiratory function recovery have not yet been developed for patients after the left ventricle geometric reconstruction (LVGR). The aim: to investigate the cardiorespiratory status of patients before and after LVGR and to evaluate the effectiveness of conventional respiratory rehabilitation for this category of patients. Materials and Methods. The study involved 43 patients who underwent two types of surgeries: 1) coronary artery bypass grafting (CABG), and 2) CABG with LVGR. Patients were divided into two groups: group I - patients after CABG, and group II - patients after CABG with LVGR. Data collection was carried out in three stages: I - before surgery, II - on the 2nd day after surgery, and III - on the 10th day after surgery. Conventional respiratory rehabilitation was conducted in both groups. Results and Discussion. The results showed a deterioration in preoperative respiratory parameters (FVC [10.3 %, p = 0.039]; FEV1 [11.9 %, p = 0.027]) and cardiac dysfunction (EF [30.2 %, p 0.001]; EDV [56.4 %, p 0.001]) in group II compared to group I. By the time of discharge, no positive dynamics were observed in most of the examined spirometry parameters in group II. In group I, dynamics were noted in almost all analyzed parameters (p 0.05). Analysis of the desaturation index (DI) revealed the presence of pronounced sleep-disordered breathing in all groups during the second postoperative night. On the 10-12th postoperative day, DI in group I reached the preoperative level, while in group II this index remained elevated by 1.56 times (p = 0.006). Conclusion. Patients after LVGR have more pronounced oxygenation reduction, which is caused by both impaired patency at the level of the proximal and middle bronchioles and restrictive disorders associated with increased extracellular fluid volume. This largely forms the pathogenetic basis for the development of respiratory complications in the early postoperative period.
Evaluation of the efficiency of the expert medical decision making system in diagnosis acute appendicitis
Authors: Burnevich Slavomir Z. , Maslenko Nikita S.
Published: July 2023

Relevance. Timely diagnosis is the basic criterion for the quality of medical care in emergency department. One of the promising directions in the prevention of diagnostic errors is the use in clinical practice of the expert decision support system (EDSS). The aim of this study was a comparative analysis of the diagnostic efficiency of EDSS in acute appendicitis (AA) at various stages of the differential diagnosis of acute abdominal pain (AAP). Materials and methods. The study performed a retrospective analysis of the diagnostic results of 150 patients with various forms of AA, followed by the processing of structured clinical, laboratory and instrumental data using the original version of EDSS. Results and Discussion. It has been established that EDSS unidirectionally and sequentially models the stages of a standard diagnostic program for examining a patient with AAP at all levels of automated assessment of symptoms and signs of AA. Depending on the final parameters of the indication, the EDSS makes it possible to differentiate the variants of AA clinical scenarios with the identification of categories of diagnostic complexity that occurred in surgical practice. The data of relevance and validity of EDSS in the differential diagnosis of AAP are presented. The role of the expert system for the intensification of the doctor’s clinical reasoning and the prevention of diagnostic errors in emergency abdominal surgery is noted. Conclusion. The data obtained indicate a comparable diagnostic efficiency of the proposed version of EDSS with the accuracy of the diagnosis of a surgeon. The results of the preclinical use of EDSS allow the clinician to recommend its use in the format of an interactive “cognitive assistant” in case of possible difficulties and doubts in the differential diagnosis of AAP.
Diagnostics and prevention of sports-related traumatic brain injury complication
Authors: Shevelev Oleg A. , Smolensky Anderei V. , Petrova Marina V. , Mengistu Elias M. , Mengistu Anastasia A. , VatsikGorodetskaya Maria V. , Khanakhmedova Umayzat G. , Menzhurenkova Darina N. , Vesnin Sergey G. , Goryanin Igor I.
Published: July 2023

Sports-related traumatic brain injuries (TBI) accounts for up to 20 % of all injuries that are obtained by athletes and its incidence rises annually due to rise in population involving in sports, growing popularity of extreme sports and high level of motivation to achieve record results among young sportsmen. The aim of the review is to present the potential benefits of using microwave radiothermometry and craniocerebral hypothermia technologies in sports-related TBI. The review considers most common form of traumatic brain injury in athletes - mild TBI, which in turn can provoke a wide range of complications and negative consequences in near and delayed periods after the injury. The main shortcomings of programs for complication prevention in treatment and rehabilitation of athletes after TBI are considered, which do not take into account the peculiarities of injury mechanisms, its significant differences from household, road or criminal injuries with brain damage. Lack of objective methods of instrumental diagnosis for injury severity is also described. In addition, pathophysiological component characteristics of sports TBI is accentuated: frequency of repetition, increasement of brain and body temperature, peripheral redistribution of blood flow and hypocapnia, which significantly affects cerebral blood flow. Based on the analysis of the available scientific literature, it is elicited that TBI is an independent cause of cerebral hyperthermia development, which significantly aggravates the consequences of the injury. Conclusions. The authors propose an innovative way to use microwave radiothermometry method as a diagnostic tool for sports-related TBI. In addition, the review highlights the main recommendations for complications prevention by using craniocerebral hypothermia technology, which reduces overall physical and cerebral hyperthermia, and augments the resistance of cerebral cortex neurons to hypoxia and trauma. However, the authors believe that the described approaches in sports medicine are not used purposefully due to lack of awareness of sports team doctors and coaches.
Ural-Volga Research Contacts and Prospects
Authors: Arzamazov Aleksey A.
Published: July 2023

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“We Post and Post, and Others Will Come to Like Us...”, or Translingual Practices in B. Anfinogenov’s Poetry
Authors: Kondratieva Natalya V. , Ilina Natalia V.
Published: July 2023

The article deals with the study of translingual practices in the works by the Udmurt poet B.V. Anfinogenov. The interest to the questions of transcultural literature is due to the importance of research in cultural diversity of multilingual regions of Russia. The methodological basis of the article is the linguistic analysis of a literary text, synthesis-generalization of the achievements of modern literary criticism, structural analysis of a poetic text, etc. The collection of poetic texts by B. Anfinogenov “Dz’ikya Promo” (2023) is used as the material for analysis. Based on the analysis, the peculiarities of translingual practices representation in the works by B. Anfinogenov are revealed, extra-textual (ethnic and cultural self-identification of the author, themes, foreign language inclusions) and intra-textual (hybrid cultural canons and codes) levels of representation of translingualism are outlined. Special attention is paid to the analysis of the role of graphic determination as well as the use of interlanguage homophony and intertextuality in transcultural literature.
Erzya Poetry in the Ural Region: the Artistic World of Dmitry Taganov
Authors: Arzamazov Aleksey A.
Published: July 2023

The article deals with the problematic and thematic contexts of the work of Dmitry Taganov, one of the most prominent representatives of modern Mordovian (Erzian) literature. D. Taganov, who was born and lives in the Ural region, personifies the literary diaspora of the Mordovians with his biography and poems. In the course of the study, it was found out that his poetic world is distinguished by an ascetic figurative system and a stable set of figurative and symbolic elements, which almost does not change from collection to collection. The study included not only original texts in the Erzya language but also Russian interlinear translations made by the author, which allow interpreting artistic features and stylistic details in two linguopoetical “projections” at once. It has been established that in his poems D. Taganov mostly avoids the actualization of the ethno-cultural component, prefers ethnically neutral lyrical plots, and pays increased attention to the psychological realities of love existence. Some motif-figurative elements connected with the poet’s professional activity in medicine are shown. An important aspect of this study is the analysis of literary translations of D. Taganov’s poems into Russian. Difficulty in understanding the original works by the translator and facts of inattentive attitude to the core parameters of the original text are demonstrated on the example of texts.
Bilingualism of A. Pudin’s Dramaturgy
Authors: Antonov Yury G. , Kabanova Julija V.
Published: July 2023

The article deals with the artistic originality of bilingualism of one of the leading modern Mordovian playwrights Alexander Pudin. The most productive types of it in the work of the playwright are defined, and the reasons for the use of two languages in the writing process are identified. The importance of the transition from one language to another is emphasized in order to expand the aesthetic boundaries of the author’s worldview and to accurately convey ethnic nuances to the foreign-language reader and viewer. The author reveals the artistic and aesthetic specificity of the author’s translation, which allowed to reveal more deeply both the conflict collisions of plays and the individual characters of carriers of national character traits. A special place is given to plays in Russian, in which the playwright immerses us in a diverse ethnic palette of perception of the surrounding reality and recreates a bright national flavor through mythological context.
Mapping models in novel metaphors and their effect on gaze behavior and default interpretations in native and target languages
Authors: Kiose Maria I.
Published: July 2023

In the study, we address the problem of existing differences in reading and understanding novel metaphors in the text fragments in native and target languages (L1 and L2), with these differences potentially attributed to both the specifics of forming analogies in native and target languages, and the mapping characteristics of metaphors. The study identifies the contingency effects of several primary metaphors onto the gaze behavior and default interpretation of textual novel metaphors in L1 (Russian) and L2 (English). To proceed, we use the text fragments in L1 and L2 containing novel metaphors appearing in more and less focal syntactic positions in a two-stage oculographic experiment. We obtain the participants’ gaze metrics values and the participants’ responses specifying the target domains of the novel metaphors, which further allows us to disclose the contingencies. Methodologically, the study is grounded in the metaphor processing theories developed in cognitive psychology, which explore the structure of analogical reasoning and associative fluency as manifesting potentially different effects in L1 and L2. To validate it, we also address the cognitive linguistic theories which provide the framework for identifying the primary metaphor models (here the models PATIENT (OBJECT) IS AGENT, PARTS ARE WHOLE, CONCRETE IS ABSTRACT) and for testing their effect onto information construal. We hypothesize that reading and understanding metaphors will proceed differently in L1 and L2, which is attributed to associative fluency in metaphor mapping in native and target languages. The experiment results do not show the differences in understanding the mapping model PATIENT (OBJECT) IS AGENT in L1 and L2, whereas these differences appear in understanding the models PARTS ARE WHOLE and CONCRETE IS ABSTRACT with higher default interpretation index in L1. The model PATIENT (OBJECT) IS AGENT is also found to stimulate higher gaze costs. The results suffice to claim that there are differences in the cognitive costs produced by primary metaphor models, which allows us to range and specify their role in information construal in L1 and L2.
Linguistic and statistical analysis of the lexical ‘Langue-Parole’ dichotomy in a restricted domain
Authors: Sheremetyeva Svetlana O. , Babina Olga I.
Published: July 2023

Development of new digital methods for analyzing the ‘Langue-Parole’ dichotomy is one of the most sought-after, but least researched problems of modern theoretical and applied linguistics. This determines the relevance of this study, the purpose of which is to develop a methodology for the automated linguastatistical analysis of a domain-related lexical layer in the context of the ‘Langue-Parole’ dichotomy and to apply the methodology to the Russian-language domain “Research on athlete integrative physiology” (RAIP). The study was conducted on the material of the Russian-language corpus including 56 RAIP domain texts of 300,000 wordforms in total published over the 2013-2020 period in the scientific journals “People. Sport. Medicine” (formerly “SUSU Bulletin. Series “Education, Healthcare, Physical Culture”), “Theory and Practice of Physical Culture”, etc. The key methodological approach is the ontological analysis of corpus data using statistical and linguistic modeling methods. The domain-specific language and speech are modeled by the corresponding lexicon and corpus, while the ‘Langue-Parole’ lexical dichotomy is represented by the values of the linguistic-statistical concept verbalization parameters of the domain concepts in the lexicon and corpus. The computational parameters include the indices of lexical diversity, structural complexity, conceptual syncretism, lexical structural complexity vs. conceptual syncretism correlation, and syncretical concept junction when verbalized in the corpus. The main results of the study are: 1) а methodology for analyzing domain-specific lexical dichotomy ‘Langue-Parole’, which can be ported to other domains and national languages; 2) the RAIP domain-related resources, including language-independent ontology, conceptually annotated Russian corpus, onto-lexicon, linguistic-statistical parameter values of the lexical ‘Langue-Parole’ dichotomy; and 3) tools that automate certain stages of the study.
Review of Maria M. Buras. 2022. Linguists Who Came in from the Cold. Moscow: AST Publishing House (Series The Great Sixties). ISBN 978-5-17-144664-2
Authors: Nikitin Oleg V.
Published: July 2023

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Polyhexamethylene Biguanide-Betaine Dressing Combined with Silver Sulfadiazine for Biofilm Control in an Advanced Cancer Wound: A Case Report
Authors: Kim Kyung Wook , Jeon Jae Hyung , Park Jong Hyun , Jeon Hong Bae
Published: July 2023

Biofilm in a wound base can cause chronic infection and a persistent immune response in the host, inhibiting wound healing. Antibiotics and antiseptics may not be effective because the protective layers of biofilms are difficult to penetrate. Polyhexamethylene biguanide-betaine (PHMB-B) has been known as an effective antiseptic agent for biofilm treatment. Here, we present a case of chronic wound biofilm management using PHMB-B combined with silver sulfadiazine in a patient with advanced breast cancer, which enabled successful flap coverage without infection. A 46-year-old female had left breast cancer with chronic wounds that had not been treated for 2 years. After chemotherapy and radiotherapy, the chronic wounds were aggravated with biofilms. Following palliative total mastectomy, surgical debridement and povidone-iodine dressings were performed. However, the wound did not display significant improvement and also caused severe pain. The povidone-iodine dressings were changed to silver sulfadiazine ointment, however this was also ineffective for controlling the biofilm. Eventually, we additionally applied PHMB-B before silver sulfadiazine which led to wound improvement with no identifiable microorganisms. Subsequently, a pedicled transverse rectus abdominis myocutaneous flap was performed without complications. Consequently, PHMB-B combined with silver sulfadiazine could effectively eradicate biofilms in a patient with advanced breast cancer.
Demodicidosis of an Intertragic Notch of the Ear That Was Misdiagnosed as a Skin Tumor: A Case Report
Authors: Heo Seung , Yang Jeong Yeol
Published: July 2023

Demodex mite infestation has variable clinical manifestations including eruptions, erythema, pustules, facial hyperpigmentation, rosacea-like lesions, and perioral dermatitis. A 62-year-old man came with a 2-year history of a slowly enlarging, asymptomatic lesion in the intertragic notch of the left ear, and the findings from an ultrasound conducted by a radiologist suggested a benign skin tumor such as an epidermal or trichilemmal cyst. After total excision, histopathology of a section of the specimen showed multiple follicular infundibula containing Demodex folliculorum in the dermal layer, and the perifollicular tissue showed granulomatous change with lymphomononuclear inflammation. This article presents a rare clinical symptom of Demodex mites in the form of a tumor-like lesion on the face.
Necessity of Tissue Culture from Clinically Uninfected Wounds in Diabetic Patients
Authors: Yun Yu-Kyeong , Han Seung-Kyu , Namgoong Sik , Moon Kyung-Chul , Jeong Seong-Ho , Dhong Eun-Sang
Published: July 2023

Background: The Infectious Diseases Society of America Clinical Practice Guidelines recommends not culturing specimens from patients with diabetes who do not show clinical signs or symptoms of local inflammation. However, in diabetic patients the local or systemic inflammatory response is commonly reduced, even in severely infected cases, owing to poor immune response. This study aimed to investigate the clinical significance of tissue cultures in patients with diabetic ulcers without clinical signs of infection.Methods: This study included 248 of 1,346 patients who had diabetic foot ulcers but did not exhibit any signs or symptoms of infection in our hospital. Tissue culture results were classified as either negative, positive culture in soft tissue or positive culture in bone. Wound healing outcomes were divided into two categories: healed without amputation or healed with amputation.Results: A significant difference existed between the negative culture and bone culture-positive groups. Patients who had a positive bone culture result were 2.1 times more likely to require amputation than those who had negative culture results. Moreover, the rate of amputation was higher in bone culture-positive patients than in soft tissue culture-positive patients.Conclusion: Our study showed that tissue culture may be required for patients with diabetic ulcers even if they do not exhibit any signs or symptoms of inflammation.
Impact of non-pharmaceutical interventions on the rate of respiratory viruses other than severe acute respiratory syndrome coronavirus 2 in the coronavirus disease 2019 pandemic
Authors: Yoon Ho Jun , Jo Young Min
Published: July 2023

Purpose: We aimed to evaluate the impact of non-pharmaceutical interventions (NPIs) on the transmission of respiratory viruses other than severe acute respiratory syndrome coronavirus 2 among children during the coronavirus disease 2019 pandemic.Methods: We analyzed the clinical and polymerase chain reaction (PCR) findings using electronic medical records of children (< 18 years) with fever or respiratory symptoms who were hospitalized via the emergency department of Wonkwang University Hospital (Iksan, Korea), from March 2018 through December 2021. The children were divided into before and after groups based on the hospitalization date relative to February 2020, starting point of the implementation of NPIs. PCR was performed using nasopharyngeal swab samples. Between the 2 groups, we compared age, sex, length of hospital stay, and PCR findings.Results: The before and after groups consisted of 3,160 and 989, respectively, showing a 68.7% decrease in the number of children undergoing PCRs after the implantation of NPIs. The after group showed higher median values of the age and length of hospital stay than the before group (Ps < 0.001). A 76.9% decrease was noted in the number of children having PCR positivities (from 1,101 [34.8%] to 254 [25.7%]; P < 0.001). Among detected viruses, an increase in the proportion was noted only in human bocavirus (from 81 [2.6%] to 54 [5.5%]; P < 0.001). In contrast, significant decreases in the proportions were found in adenovirus, enterovirus, influenza A and B, respiratory syncytial viruses A and B, human coronaviruses (229E, NL63, and OC43) and human metapneumovirus.Conclusion: NPIs may be effective in reducing the transmission of respiratory viruses other than severe acute respiratory syndrome coronavirus 2 among children during the pandemic.
TELEVISÃO, EDUCAÇÃO E RELIGIOSIDADE: EXPERIÊNCIAS NO CAMPO DO ENSINO RELIGIOSO E DA SOCIOLOGIA
Authors: Brasil Taciana , Pereira Paulo Vinícius Faria
Published: July 2023

O programa Se Liga na Educação foi uma iniciativa da Secretaria de Estado da Educação de Minas Gerais, para atendimento dos estudantes da rede estadual durante a pandemia. Após o término do isolamento social, o programa continuou sendo exibido em televisão aberta e através da internet. Este trabalho apresenta relatos de experiência docente nos conteúdos Ensino Religioso e Sociologia, enfatizando os desafios e potenciais de trabalhar questões relacionadas à religião e religiosidade em condições de ampla exibição. Concluímos que a exposição de nosso trabalho docente é um importante meio para conscientização e divulgação dos objetivos da BNCC para o trabalho com temas relacionados à religião e à religiosidade.
APROXIMAÇÕES FILOSÓFICAS E HISTÓRICAS ENTRE A TEOLOGIA DA EDUCAÇÃO E A PEDAGOGIA SOCIAL
Authors: Vieira Klyvia Larissa de Andrade Silva , Souza Sueli Ribeiro Mota
Published: July 2023

O presente artigo apresenta um recorte histórico da Teologia da Educação em seus fundamentos filosóficos e pedagógicos. Nesse sentido apresentamos os fundamentos que aproximam a Filosofia e a Teologia, na compreensão da realidade.  As práticas educativas estão presentes na história da humanidade e na sua relação existencial e transcendental. Assim, a Teologia da Educação presente na religiosidade da igreja cristã elabora um fundamento educativo, com vistas a propagação e manutenção de sua profissão. A Pedagogia Social compreende que práticas educativas não são exclusivas de espaços formais de educação. Assim, objetivamos fomentar uma reflexão dos aspectos educativos que estão presentes na história e nos pressupostos filosóficos na religião e na religiosidade.
ENSINO RELIGIOSO PARA A AUTONOMIA: NOTAS SOBRE RELIGIOSIDADE, EDUCAÇÃO E DIVERSIDADE
Authors: Rodrigues Elisa , Sarto Giovanna
Published: July 2023

Em um projeto de educação para a autonomia, a noção de cidadania é importante e é dotada de significado político, tendo em vista que objetiva a formação de sujeitos autônomos, criativos e críticos, aptos ao exercício responsável de suas liberdades, bem como de suas obrigações. Nesse sentido, todo currículo é dinâmico e envolve diversos agentes sociais que partem de diferentes ideologias. Por isso mesmo, todo currículo é também um campo de disputa. No presente artigo, apresentamos uma discussão sobre as disputas envolvendo o Ensino Religioso, e advogamos por um currículo científico construído nas e pelos fundamentos epistemológicos da Ciência da Religião, como área de conhecimento que serve teórica e metodologicamente ao Ensino Religioso. Articulando um breve histórico da temática ao processo de laicidade no Brasil, tecemos uma distinção, ainda que limitada, entre religião e religiosidade, com vistas ao aprimorando e expansão da compreensão do que seja o objeto do Ensino Religioso, a saber: o fenômeno religioso. Defendemos que é através do angariamento das bases teóricas de um Ensino Religioso laico e reflexivo que se constrói um projeto de formação de estudantes criativos e autônomos, fortalecendo um modelo de educação de e para a diversidade.
Estudio comparativo de arcillas decolorantes utilizadas industrialmente en la operación de blanqueo de aceites de palma
Authors: Rodríguez Mejía Javier Mauricio , Torres Ortega Jesús Alfonso
Published: July 2023

The palm oil bleaching is an important operation in the refinement in which usually appears inconvenient, although the company’s processors have developed technical to control the quality of the crude oil and to conduct the operation easier of bleaching, isconsidered unstable due to the variables that are handled. During the bleaching is retires of the oil soap plans, metals, phospholipids and substances that contribute colour, by means of the clay action launderers, who have pores and great superficial area, where the polluting agents are absorbed by physical effect, giving to purity and quality to the processed oil. In the national market are several clay marks; therefore arose the interest to determine that clay launderer displays better results in yield, removal of polluting agents and good properties to the refined oil. With the analyzed information of the experimentation, the incidences of each variable was evaluated and were the best conditions of agreed operation to the theoretical information and the experimentalresults that are presented in this article. In Colombia the Tonsil marks are in great proportion (Sud Chemie) with 35%, Pure Flow (Oil Dri) with 50% and Filtrol (Engelhard) with 15% of the market. Other marks are not due to their lack of competitiveness in price.
Hantzsch ester modified asymmetric BODIPY probe with ultra-high sensitivity for ultra-fast detection of endogenous hypochlorite in living cells
Authors: Zhu Tianli , Zhao Mengting , Wang Rongcheng , Dong Chenjun , Dong Xuemei , Sun Jie , Sun Lixin , Zhao Chunchang
Published: July 2023

Hypochlorite (ClO) is an important reactive oxygen
species produced by the immune system to fight off invading pathogens,
but its over-expression can interfere with normal physiological process
and induce serious diseases. Although a variety of molecular probes have
been reported for detecting ClO, the development of
advanced fluorescent tools with faster response and higher sensitivity
to precisely monitor ClO remains a challenge. In this
work, two Hantzsch ester (a derivative of 1,4-dihydropyridine) derived
fluorescent probes MeDHP-BCl and MeDHP-PhBCl were constructed based on
asymmetric BODIPY-matrix. These probes exhibit significant fluo-rescence
turn-on in the ultra-sensitive (detection limit < 1 nM) and
ultra-fast response (≤ 5 s) to ClO, the reaction has
determined to be a highly selective N-Chlorination of Hantzsch ester
which cannot be activated by various common bioactive species, including
nitric ox-ide (NO) that could oxidize Hantzsch ester under aerobic
physiological conditions in most reports. MeDHP-PhBCl possess a
relatively longer fluorescence emission wavelength and higher quantum
yield after activation, while more notably, MeDHP-BCl displayed lower
cytotoxicity and more remarkable fluorescence increasement in the
response to ClO, enabling selective and precise
visualization of endogenous ClO over-expression in
living RAW264.7 cells.
Long-term performance of single-lap joints: review, challenges and prospects in civil engineering
Authors: Shu Yue , Qiang Xuhong , Jiang Xu , Dong Hao
Published: July 2023

Compared with traditional technology, bonding technology is more
suitable for civil structure reinforcement because of its
cost-efficiency and superior mechanical properties. As one of the
simplest forms of adhesive joints, numerous studies have been conducted
on the performance of single-lap joints (SLJs). However, research on the
long-term performance of SLJs requires better organization and
comprehension. This paper aims to investigate the long-term performance
and optimization design of SLJs. The main factors influencing the
long-term performance of SLJs from both material and component levels
are discussed. The moisture diffusion mechanisms of bulk adhesives and
the degradation mechanisms of SLJs are explored. Moreover, the
optimization design of SLJs focuses on evaluating the overlap length,
adhesive layer thicknesses, and changes in adhesives along the overlap
length based on available literature. This paper can be employed to
improve the shear strength and long-term performance of SLJs and to
provide insights into their challenges and prospects.
Mixed type of curves in the Lorentz-Minkowski space
Authors: Chen Liang , Takahashi Masatomo
Published: July 2023

For a non-lightlike non-degenerate regular curve, we have the arc-length
parameter and the Frenet-Serret type formula by using a moving frame
like as a regular space curve in the Euclidean space. If a point of the
curve moves between spacelike and timelike regions, then there is a
lightlike point. In this paper, we consider mixed types of not only
regular curves but also curves with singular points. In order to
consider mixed type of curves with singular points, we introduce a
frame, so-called the lightcone frame, and lightcone framed curves. We
investigate differential geometric properties of mixed type curves by
using the lightcone frame.
A feature-based Modeling Strategy for Managing Stakeholders
Authors: Ignaim Karam , Fernandes Joao
Published: July 2023

Successful product development is mostly based on how well ideas,
opinions, and contributions from stakeholders are taken into account.
There are signs that the way a project manager involves stakeholders in
the project is directly linked to how well software products are
delivered. Engagement of stakeholders enables organizations to
proactively consider the requirements and desires of anyone with a stake
in the stakeholder management process. For the stakeholder management
process to work, all stakeholders must be listed in a reference
document, and their involvement in the process must be kept up-to-date.
The main goal of this study is to find a solution to this problem by
coming up with a feature-based strategy for capturing and documenting
the right stakeholders during the stakeholder management process. The
strategy also supports ongoing monitoring of the status and attributes
of stakeholders during this process. To evaluate the strategy, we have
conducted a case study on the stakeholder management process of Smart
Home to assess the ease of use, usefulness, effectiveness, and
efficiency of the proposed strategy. The results reveal that our
strategy of documenting and keeping track of the stakeholders makes the
stockholder management process more effective and efficient. The results
have also shown that the proposed strategy is considered easy to learn
and useful by the software engineers.
E-Commerce Security and Customer’s Use of E-Commerce Platforms among Federal Government Personnel in Ibadan, Nigeria
Authors:   Department of Data and Information Science, Faculty of Multidisciplinary Studies University of Ibadan, Ibadan, Nigeria, Ogunsola Kemi , Enwerem Patrick Ejike
Published: July 2023

Advancement in internet infrastructure has aided the rise of online businesses called electronic commerce (e-commerce). However, the security of e-commerce has assumed heightened dimensions in recent times as news of security threats on popular websites abounds in literature and the media. This study seeks to investigate e-commerce security and use among personnel of federal ministries and agencies in Ibadan, Oyo State and provide answers to three research questions. Survey design was adopted and data were collected using a questionnaire. The study employed stratified random sampling technique to select the ministries and agencies, while convenience sampling technique was used to select 262 respondents. Data were analysed with SPSS version 26 using descriptive statistics and Spearman rank correlation. The findings revealed that both the frequency of use and perception of e-commerce among personnel in federal ministries and agencies in Ibadan, Oyo State, are moderately high. There exists a significant positive relationship between e-commerce security and the use of e-commerce among personnel in federal ministries and agencies in Ibadan. Among others, it was recommended that e-commerce vendors should endeavour to take the security of their platform seriously and invest in it. Keywords: E-security, Electronic commerce, E-business, Government personnel, Online marketing Ogunsola, K. & Enwerem, P.E. (2023): E-Commerce Security and Customer’s Use of E-Commerce Platforms among Federal Government Personnel in Ibadan, Nigeria. Journal of Advances in Mathematical & Computational Science. Vol. 11, No. 1. Pp 27-44 dx.doi.org/10.22624/AIMS/MATHS/V11N1P3. Available online at www.isteams.net/mathematics-computationaljournal.
Clinical and radiologic study of total knee replacement arthroplasty using Doujet GF bone cement (liquid-powder bone cement containing gentamicin)
Authors: Choi Sungwook , Yoon Seong-meen , Rho Joseph Y. , Son In-seok
Published: July 2023

Gentamicin-loaded bone cement used in total joint arthroplasty is indispensable, as it provides stability by directly binding the surfaces of implants and bones. Depending on multiple factors, including the material of the bone cement used, common complications, such as aseptic loosening, osteolysis, and infection can occur postoperatively. In clinical practice, Doujet bone cement is easy to handle (pre-packed all-in-one system), and has shown low failure rates and non-inferior results compared with similar available products. We conducted a retrospective comparative study to analyze the clinical and radiological results of each bone cement group to establish the safety and usefulness of Doujet bone cement. From July 2020 to July 2022, we enrolled 198 patients in this study after an average follow-up period of 37 months (range, 6–48 months). In 99 patents, Doujet® bone cement (Injecta, Gunpo, Korea) was used for total knee arthroplasty (TKA), while Refobacin® bone cement (Biomet, Warsaw, IN, USA) was used in 99 patients. The average range of motion (ROM) of the knee increased by 2.4° (from 127.0° preoperatively to 129.4° postoperatively) in the Doujet group, and by 0.1° (from 128.7° to 128.8°) in the Refobacin group (P=0.701). The Western Ontario and McMaster Universities (WOMAC) osteoarthritis index scores decreased from 44.1 to 7.8 in the Doujet group, and from 44.2 to 6.3 in the Refobacin group (P=0.162). Complications, such as osteolysis or post-operative wound infection, did not occur in more than two cases in both groups. The WOMAC and ROM of the knee in both groups had no clinical differences. Both Doujet and Refobacin similarly showed low complication rates after TKA.
Contribution to methods and techniques of scientific research: Structure of the scientific research report - 5. Conclusions
Authors: Rankovic Nenad
Published: July 2023

Drawing conclusions from the research is probably the most important section
of the research report. Inference and conclusions, as a product of this
process, are based on research findings, which form a factual basis for
drawing conclusions. They highlight the specific importance of the work and
allow for a certain cognition of science and practice, and are tasked with
identifying key research findings and linking them with what was said in the
introduction.
Click mediated synthesis of functionalized glycolipids with peptide-peptoid linkages
Authors: Singhamahapatra Anadi , Pattnaik Chinmayee , Kar Prasad , Nayak Chandra , Sahoo Narayan , Sahoo Satyanarayan
Published: July 2023

The present work describes the synthesis of a new class of glycolipids with systematic variations in the linkage region, as well as in the aglycon part using Cu(I) catalyzed click reaction. The linkage region between sugar and the aglycon part was diversified using amide, amido-triazole and 5-benzoyl triazole moieties. The structural diversity of glycolipids was further amplified by incorporating several polar peptide foldamer groups such as triazole, amide, peptide, or N-aryl peptoid in the aglycon part. The newly designed glycolipids were derived from the amalgamation of different peptide bond mimics. This work reports the first use of N-aryl peptoid in the synthesis of glycolipids. The newly synthesized glycolipids were characterized using different spectroscopic and spectrometric analyses. The impact of the amide bond as well as the triazole ring in the linkage region on the morphology of the glycolipids was analysed by comparing their self-assemblies using SEM analysis. The geometries of the glycolipids were also optimized using density functional theory and the optimized structures were found to be minima in the potential energy surfaces.