bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1-4 from Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
Authors: Wang Zhen , Zheng Min , Li Zhichuan , Li Ruiguo , Jia Lijun , Xiong Xiufang , Southall Noel , Wang Shaomeng , Xia Menghang , Austin Christopher P. , Zheng Wei , Xie Zijian , Sun Yi
Published: April 2023

Supplementary Figures 1-4 from Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
Supplementary Figure 1 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Authors: Wada Satoshi , Yoshimura Kiyoshi , Hipkiss Edward L. , Harris Tim J. , Yen Hung-Rong , Goldberg Monica V. , Grosso Joseph F. , Getnet Derese , Demarzo Angelo M. , Netto George J. , Anders Robert , Pardoll Drew M. , Drake Charles G.
Published: April 2023

Supplementary Figure 1 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Supplementary Figure 4 from Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Authors: Jagani Zainab , Song Keli , Kutok Jeffery L. , Dewar M. Rajan , Melet Armelle , Santos Tanya , Grassian Alexandra , Ghaffari Saghi , Wu Catherine , Ren Ruibao , Rodin Heather Yeckes , Miller Kenneth , Khosravi-Far Roya
Published: April 2023

Supplementary Figure 4 from Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Supplementary Figure 1 from Tumor Apoptotic Bodies Inhibit CTL Responses and Antitumor Immunity via Membrane-Bound Transforming Growth Factor-β1 Inducing CD8+ T-Cell Anergy and CD4+ Tr1 Cell Responses
Authors: Xie Yufeng , Bai Ou , Yuan Jinying , Chibbar Rajni , Slattery Karen , Wei Yangdou , Deng Yulin , Xiang Jim
Published: April 2023

Supplementary Figure 1 from Tumor Apoptotic Bodies Inhibit CTL Responses and Antitumor Immunity via Membrane-Bound Transforming Growth Factor-β1 Inducing CD8+ T-Cell Anergy and CD4+ Tr1 Cell Responses
Supplementary Methods from Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
Authors: Di Vizio Dolores , Kim Jayoung , Hager Martin H. , Morello Matteo , Yang Wei , Lafargue Christopher J. , True Lawrence D. , Rubin Mark A. , Adam Rosalyn M. , Beroukhim Rameen , Demichelis Francesca , Freeman Michael R.
Published: April 2023

Supplementary Methods from Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
Supplementary Table 1 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Authors: Wu Xianglin , Mondal Gourish , Wang Xianshu , Wu Jianmin , Yang Lin , Pankratz Vernon S. , Rowley Matthew , Couch Fergus J.
Published: April 2023

Supplementary Table 1 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Supplementary Figure Legends 1-6 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Authors: Wu Xianglin , Mondal Gourish , Wang Xianshu , Wu Jianmin , Yang Lin , Pankratz Vernon S. , Rowley Matthew , Couch Fergus J.
Published: April 2023

Supplementary Figure Legends 1-6 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Supplementary Figure 4 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Authors: Wu Xianglin , Mondal Gourish , Wang Xianshu , Wu Jianmin , Yang Lin , Pankratz Vernon S. , Rowley Matthew , Couch Fergus J.
Published: April 2023

Supplementary Figure 4 from Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair
Supplementary Table 6 from A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice
Authors: Dupuy Adam J. , Rogers Laura M. , Kim Jinsil , Nannapaneni Kishore , Starr Timothy K. , Liu Pentao , Largaespada David A. , Scheetz Todd E. , Jenkins Nancy A. , Copeland Neal G.
Published: April 2023

Supplementary Table 6 from A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice
Supplementary Figure 3 from Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
Authors: Lou Yuanmei , McDonald Paul C. , Oloumi Arusha , Chia Stephen , Ostlund Christina , Ahmadi Ardalan , Kyle Alastair , auf dem Keller Ulrich , Leung Samuel , Huntsman David , Clarke Blaise , Sutherland Brent W. , Waterhouse Dawn , Bally Marcel , Roskelley Calvin , Overall Christopher M. , Minchinton Andrew , Pacchiano Fabio , Carta Fabrizio , Scozzafava Andrea , Touisni Nadia , Winum Jean-Yves , Supuran Claudiu T. , Dedhar Shoukat
Published: April 2023

Supplementary Figure 3 from Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
Supplemental Methods and Materials, Supplementary Figures 1-12, Supplementary Figure Legends from Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas
Authors: Naylor Tara L. , Tang Huaping , Ratsch Boris A. , Enns Andreas , Loo Alice , Chen Liqing , Lenz Peter , Waters Nigel J. , Schuler Walter , Dörken Bernd , Yao Yung-mae , Warmuth Markus , Lenz Georg , Stegmeier Frank
Published: April 2023

Supplemental Methods and Materials, Supplementary Figures 1-12, Supplementary Figure Legends from Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas
Supplementary Figure 9 from Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Authors: Yang Yizeng , Nakagawa Hiroshi , Tetreault Marie-Pier , Billig Janelle , Victor Noel , Goyal Abha , Sepulveda Antonia R. , Katz Jonathan P.
Published: April 2023

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Supplementary Figure 7 from Loss of Transcription Factor KLF5 in the Context of p53 Ablation Drives Invasive Progression of Human Squamous Cell Cancer
Authors: Yang Yizeng , Nakagawa Hiroshi , Tetreault Marie-Pier , Billig Janelle , Victor Noel , Goyal Abha , Sepulveda Antonia R. , Katz Jonathan P.
Published: April 2023

PDF file - 602K
Supplementary Methods and Materials from Deletion of the Proline-Rich Region of the Murine Metastasis Susceptibility Gene Brd4 Promotes Epithelial-to-Mesenchymal Transition- and Stem Cell-Like Conversion
Authors: Alsarraj Jude , Walker Renard C. , Webster Joshua D. , Geiger Thomas R. , Crawford Nigel P.S. , Simpson R. Mark , Ozato Keiko , Hunter Kent W.
Published: April 2023

Supplementary Methods and Materials from Deletion of the Proline-Rich Region of the Murine Metastasis Susceptibility Gene Brd4 Promotes Epithelial-to-Mesenchymal Transition- and Stem Cell-Like Conversion
Supplementary Figure 2 from Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Authors: Muthana Munitta , Giannoudis Athina , Scott Simon D. , Fang Hsin-Yu , Coffelt Seth B. , Morrow Fiona J. , Murdoch Craig , Burton Julian , Cross Neil , Burke Bernard , Mistry Roshna , Hamdy Freddie , Brown Nicola J. , Georgopoulos Lindsay , Hoskin Peter , Essand Magnus , Lewis Claire E. , Maitland Norman J.
Published: April 2023

Supplementary Figure 2 from Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Supplementary Figure 9 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases
Authors: von Scheidt Bianca , Leung Patrick S.K. , Yong Michelle C.R. , Zhang Yu , Towne Jennifer E. , Smyth Mark J. , Teng Michele W.L.
Published: April 2023

PDF file - 96K, IL-23 expression is detected in MHCIIhiCD11c+CD11b+ cells but not in other populations in B16F10 tumor bearing lungs.
Supplemental Methods from Snail1-Expressing Fibroblasts in the Tumor Microenvironment Display Mechanical Properties That Support Metastasis
Authors: Stanisavljevic Jelena , Loubat-Casanovas Jordina , Herrera Mercedes , Luque Tomás , Peña Raúl , Lluch Ana , Albanell Joan , Bonilla Félix , Rovira Ana , Peña Cristina , Navajas Daniel , Rojo Federico , García de Herreros Antonio , Baulida Josep
Published: April 2023

Supplemental Methods
Supplementary Tables S1-S4 from Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer
Authors: Peng Jin , Hamanishi Junzo , Matsumura Noriomi , Abiko Kaoru , Murat Kumuruz , Baba Tsukasa , Yamaguchi Ken , Horikawa Naoki , Hosoe Yuko , Murphy Susan K. , Konishi Ikuo , Mandai Masaki
Published: April 2023

Pathway analyses identified the top 100 upregulated pathways related to immune response following administration of chemotherapy to clinical primary ovarian cancer samples from the microarray dataset GSE15622 (S1); Clinicopathological features of 21 ovarian cancer patients before and after chemotherapy at Kyoto University (S2); The intensity of the staining scores of NF-κB p65 or PD-L1 was detected and analyzed by immunohistochemistry using anti-NF-κB p65 or anti-PD-L1 antibodies (S3); The numbers of cells positive for CD8, CD4, or Gr-1 were determined by immunohistochemistry using anti-CD8, anti-CD4, or anti-Gr-1antibodies; original magnification 200x (S4).
Supplementary Figure S6 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: April 2023

Supplementary Figure S6. Localization of miR-135 and miR-203 binding sites within the human Runx2 3'UTR.
Supplemental Figure 2 from BH3 Inhibitor Sensitivity and Bcl-2 Dependence in Primary Acute Lymphoblastic Leukemia Cells
Authors: Alford Sarah E. , Kothari Anisha , Loeff Floris C. , Eichhorn Joshua M. , Sakurikar Nandini , Goselink Henriette M. , Saylors Robert L. , Jedema Inge , Falkenburg J.H. Frederik , Chambers Timothy C.
Published: April 2023

Supplemental Figure 2: Primary ALL cells are highly sensitive to ABT-199.
Supplemental Table S5 from Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Authors: Neskey David M. , Osman Abdullah A. , Ow Thomas J. , Katsonis Panagiotis , McDonald Thomas , Hicks Stephanie C. , Hsu Teng-Kuei , Pickering Curtis R. , Ward Alexandra , Patel Ameeta , Yordy John S. , Skinner Heath D. , Giri Uma , Sano Daisuke , Story Michael D. , Beadle Beth M. , El-Naggar Adel K. , Kies Merrill S. , William William N. , Caulin Carlos , Frederick Mitchell , Kimmel Marek , Myers Jeffrey N. , Lichtarge Olivier
Published: April 2023

Supplemental Table S5. Stratification of TP53 mutations by either disruptive or truncating systems in the training set did not identify a subset of mutations with decreased overall survival.
Supplemental Table S1 from Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Authors: Neskey David M. , Osman Abdullah A. , Ow Thomas J. , Katsonis Panagiotis , McDonald Thomas , Hicks Stephanie C. , Hsu Teng-Kuei , Pickering Curtis R. , Ward Alexandra , Patel Ameeta , Yordy John S. , Skinner Heath D. , Giri Uma , Sano Daisuke , Story Michael D. , Beadle Beth M. , El-Naggar Adel K. , Kies Merrill S. , William William N. , Caulin Carlos , Frederick Mitchell , Kimmel Marek , Myers Jeffrey N. , Lichtarge Olivier
Published: April 2023

Supplemental Table S1. Summary of patient data and prognostic data for both the test and validation datasets.
Supplemental Figure S2 from Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Authors: Neskey David M. , Osman Abdullah A. , Ow Thomas J. , Katsonis Panagiotis , McDonald Thomas , Hicks Stephanie C. , Hsu Teng-Kuei , Pickering Curtis R. , Ward Alexandra , Patel Ameeta , Yordy John S. , Skinner Heath D. , Giri Uma , Sano Daisuke , Story Michael D. , Beadle Beth M. , El-Naggar Adel K. , Kies Merrill S. , William William N. , Caulin Carlos , Frederick Mitchell , Kimmel Marek , Myers Jeffrey N. , Lichtarge Olivier
Published: April 2023

Supplemental Figure S2. Cellular proliferation is independent of TP53 status.
Supplemental data from miR30a Inhibits LOX Expression and Anaplastic Thyroid Cancer Progression
Authors: Boufraqech Myriem , Nilubol Naris , Zhang Lisa , Gara Sudheer Kumar , Sadowski Samira M. , Mehta Amit , He Mei , Davis Sean , Dreiling Jennifer , Copland John A. , Smallridge Robert C. , Quezado Martha M. , Kebebew Electron
Published: April 2023

Legends for supplemental figures
Supplementary Table 4 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: April 2023

List of SNPs successfully genotypes in the NCI/MD Case Control study.
Supplementary Table S1 from Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2
Authors: Sancisi Valentina , Gandolfi Greta , Ambrosetti Davide Carlo , Ciarrocchi Alessia
Published: April 2023

Supplementary Table S1. Primers and probes sequences.
Supplementary Figure S1 from Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2
Authors: Sancisi Valentina , Gandolfi Greta , Ambrosetti Davide Carlo , Ciarrocchi Alessia
Published: April 2023

Supplementary Figure S1. Additional luciferase data and bioinformatic analysis on RUNX2 3'UTR and ENH3.
Supplementary Figure S2 from β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells
Authors: Hong Yuan , Manoharan Indumathi , Suryawanshi Amol , Majumdar Tanmay , Angus-Hill Melinda L. , Koni Pandelakis A. , Manicassamy Balaji , Mellor Andrew L. , Munn David H. , Manicassamy Santhakumar
Published: April 2023

Supplementary Figure S2. DCs express vitamin A-metabolizing enzymes in response to EG7 tumor.
Supplementary Materials and Methods from p21 Ablation in Liver Enhances DNA Damage, Cholestasis, and Carcinogenesis
Authors: Ehedego Haksier , Boekschoten Mark V. , Hu Wei , Doler Carina , Haybaeck Johannes , Gaβler Nikolaus , Müller Michael , Liedtke Christian , Trautwein Christian
Published: April 2023

Supplementary Materials and Methods. Description of additional methods and procedures used in the study. Also includes Supplementary Reference.
Supplementary Figure Legends from Stem Cell Transplantation Reverses Chemotherapy-Induced Cognitive Dysfunction
Authors: Acharya Munjal M. , Martirosian Vahan , Chmielewski Nicole N. , Hanna Nevine , Tran Katherine K. , Liao Alicia C. , Christie Lori-Ann , Parihar Vipan K. , Limoli Charles L.
Published: April 2023

Legend for Supplementary Figures S1-S2.
Supplementary Tables S1-S2 from High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21–Mediated Matrix Metalloproteinase Activity
Authors: Chen Man , Liu Yao , Varley Patrick , Chang Ying , He Xing-xing , Huang Hai , Tang Daolin , Lotze Michael T. , Lin Jusheng , Tsung Allan
Published: April 2023

Supplementary Tables S1-S2. Primer pairs for qRT-PCR (S1); Oligonucleotides used for cloning RECK/TIMP3 3'UTR to pMIR-REPORT (S2).
Supplemental Figure Legends from AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor–Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment
Authors: Daurio Natalie A. , Tuttle Stephen W. , Worth Andrew J. , Song Ethan Y. , Davis Julianne M. , Snyder Nathaniel W. , Blair Ian A. , Koumenis Constantinos
Published: April 2023

Supplemental Figure Legends for S1-S3 and tables S1-S2
Supplementary Figures from Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer
Authors: Thomson John P. , Ottaviano Raffaele , Unterberger Elif B. , Lempiäinen Harri , Muller Arne , Terranova Remi , Illingworth Robert S. , Webb Shaun , Kerr Alastair R.W. , Lyall Marcus J. , Drake Amanda J. , Wolf C. Roland , Moggs Jonathan G. , Schwarz Michael , Meehan Richard R.
Published: April 2023

17 Supplementary Figures supporting the data and interpretation presented in the main manuscript.
SUPPLEMENTARYTABLE S2 from Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer
Authors: Thomson John P. , Ottaviano Raffaele , Unterberger Elif B. , Lempiäinen Harri , Muller Arne , Terranova Remi , Illingworth Robert S. , Webb Shaun , Kerr Alastair R.W. , Lyall Marcus J. , Drake Amanda J. , Wolf C. Roland , Moggs Jonathan G. , Schwarz Michael , Meehan Richard R.
Published: April 2023

Lists of genes transcritpionally altered following chronic PB exposure and in the resulting liver tumours (see figure 4a)
Supplemental Figures 1 - 6 from l-Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells
Authors: Fletcher Matthew , Ramirez Maria E. , Sierra Rosa A. , Raber Patrick , Thevenot Paul , Al-Khami Amir A. , Sanchez-Pino Dulfary , Hernandez Claudia , Wyczechowska Dorota D. , Ochoa Augusto C. , Rodriguez Paulo C.
Published: April 2023

Supplemental Figure 1. Peg-Arg I blocks T cell proliferation and IFNy production. Supplemental Figure 2. Peg-Arg I does not alter T cell percentages in naive mice. Supplemental Figure 3. Effects of peg-Arg I on T-cell glycolysis. Supplemental Figure 4. ASS-1 Silencing in T-cells. Supplemental Figure 5. Asparaginase depletion induces MDSC accumulation. Supplemental Figure 6. Peg-Arg I increases arginase activity in CD11b+ Gr1+ cells.
Supplementary Figure S4 from CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ
Authors: Yan Hangyi H. , Jiang Jian , Pang Yanli , Achyut B.R. , Lizardo Michael , Liang Xinhua , Hunter Kent , Khanna Chand , Hollander Christine , Yang Li
Published: April 2023

CCL9 promotes tumor cell survival and colonization.
Supplementary Table 3 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Pharmacokinetic/pharmacodynamic (PK/PD) analysis.
Supplementary Figure S2 from CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ
Authors: Yan Hangyi H. , Jiang Jian , Pang Yanli , Achyut B.R. , Lizardo Michael , Liang Xinhua , Hunter Kent , Khanna Chand , Hollander Christine , Yang Li
Published: April 2023

CCR1 expression in tumor cells.
Supplementary Figure 9 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Chemical structure and pharmacokinetic properties of the small-molecular weight inhibitor CWP232228.
Supplementary Materials and Methods, Supplementary Figures 1 through 4 and Supplementary Tables 1 through 4 from Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications
Authors: Vasudevan Divya , Hickok Jason R. , Bovee Rhea C. , Pham Vy , Mantell Lin L. , Bahroos Neil , Kanabar Pinal , Cao Xing-Jun , Maienschein-Cline Mark , Garcia Benjamin A. , Thomas Douglas D.
Published: April 2023

Supplementary Materials and Methods. Figure S1. Nitric oxide induces significant changes in histone posttranslational modifications. Figure S2. NO-mediated gene expression changes are consistent with the induction of an oncogenic phenotype. Figure S3. Nitric oxide alters the distribution patterns of H3K9ac and H3K9me2 across the genome. Figure S4. NO-upregulated genes with a new promoter-associated H3K9ac peak are involved in critical tumorigenic pathways. Table S1. NO-mediated changes in global levels of histone acetylation. Table S2. List of NO-regulated miRNAs (1.5 Fold Change cut-off). Table S3. Control ChIP-PCR primer sequences. Table S4. List of transcription factors with binding motifs found exclusively around promoters of upregulated genes with a new NO-induced H3K9ac peak.
Supplementary Figure 6 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Potential toxic effects of CWP232228 in nude mice.
Table S3 from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
Authors: Wu Min-Zu , Chen Su-Feng , Nieh Shin , Benner Christopher , Ger Luo-Ping , Jan Chia-Ing , Ma Li , Chen Chien-Hung , Hishida Tomoaki , Chang Hong-Tai , Lin Yaoh-Shiang , Montserrat Nuria , Gascon Pedro , Sancho-Martinez Ignacio , Izpisua Belmonte Juan Carlos
Published: April 2023

Table S3: List of antibodies used in this study.
Supplementary Figure 4 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Effect of CWP232228 on the growth of BCSCs obtained from human primary breast cancers.
Supplementary Figure 13 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Effect of CWP232228 on the production of IGF-I.
Supplementary Figure 11 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

The effects of CWP232228 on body weight in xenograft-bearing mice.
Supplementary Figure 1 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Sphere-forming 4T1 cell culture leads to the expression of stem cell markers.
Supplementary Figures S1-5 from Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis
Authors: Bertolini Giulia , D'Amico Lucia , Moro Massimo , Landoni Elena , Perego Paola , Miceli Rosalba , Gatti Laura , Andriani Francesca , Wong Donald , Caserini Roberto , Tortoreto Monica , Milione Massimo , Ferracini Riccardo , Mariani Luigi , Pastorino Ugo , Roato Ilaria , Sozzi Gabriella , Roz Luca
Published: April 2023

Figure S1. Integrated strategies to detect disseminated tumor cells in murine lung. Figure S2. Effect of cisplatin and CTCE-9908 combination therapy on lung tumor growth and dissemination. Figure S3. Time course analysis of metastatic CICs during lung colonization. Figure S4. Functional studies of lung-DTCs from PDX models. Figure S5. EMT induction provides tumor cells with migratory and stemness features.
Supplementary Figure 5 from Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer
Authors: Milagre Carla S. , Gopinathan Ganga , Everitt Gemma , Thompson Richard G. , Kulbe Hagen , Zhong Haihong , Hollingsworth Robert E. , Grose Richard , Bowtell David D.L. , Hochhauser Daniel , Balkwill Frances R.
Published: April 2023

Supplementary Figure 5. Effects of anti-IL-6 on nuclear ErbB-1.
Supplementary Figure 4 from Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer
Authors: Milagre Carla S. , Gopinathan Ganga , Everitt Gemma , Thompson Richard G. , Kulbe Hagen , Zhong Haihong , Hollingsworth Robert E. , Grose Richard , Bowtell David D.L. , Hochhauser Daniel , Balkwill Frances R.
Published: April 2023

Supplementary Figure 4. Nuclear ErbB-1 in IGROV-1 cells.
Supplementary Figure S1 from NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth
Authors: Satoh Hironori , Moriguchi Takashi , Saigusa Daisuke , Baird Liam , Yu Lei , Rokutan Hirofumi , Igarashi Keiko , Ebina Masahito , Shibata Tatsuhiro , Yamamoto Masayuki
Published: April 2023

Ki67 immuno-staining and H.E staining in the Keap1-wt mice and Keap1-kd mice.
Supplementary Figure 3 from Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer
Authors: Milagre Carla S. , Gopinathan Ganga , Everitt Gemma , Thompson Richard G. , Kulbe Hagen , Zhong Haihong , Hollingsworth Robert E. , Grose Richard , Bowtell David D.L. , Hochhauser Daniel , Balkwill Frances R.
Published: April 2023

Supplementary Figure 3: Targeting EGFR and IL-6 reduces compensation.
Supplementary Methods from β-Arrestin-1 Mediates Nicotine-Induced Metastasis through E2F1 Target Genes That Modulate Epithelial–Mesenchymal Transition
Authors: Pillai Smitha , Trevino Jose , Rawal Bhupendra , Singh Sandeep , Kovacs Michelle , Li Xueli , Schell Michael , Haura Eric , Bepler Gerold , Chellappan Srikumar
Published: April 2023

Supplementary materials and methods
Supplementary Tables 1 - 3 from Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma
Authors: Lin De-Chen , Xu Liang , Chen Ye , Yan Haiyan , Hazawa Masaharu , Doan Ngan , Said Jonathan W. , Ding Ling-Wen , Liu Li-Zhen , Yang Henry , Yu Shizhu , Kahn Michael , Yin Dong , Koeffler H. Phillip
Published: April 2023

Supplementary Table 1.Summary of somatic PARK2 mutations. Supplementary Table 2. Sequences of shRNAs and siRNAs. Supplementary Table 3. Sequences of primers used for qRT-PCR.
Supplementary Figure Legend from IKKβ Enforces a LIN28B/TCF7L2 Positive Feedback Loop That Promotes Cancer Cell Stemness and Metastasis
Authors: Chen Chong , Cao Fengqi , Bai Lipeng , Liu Yan , Xie Junling , Wang Wei , Si Qin , Yang Jian , Chang Antao , Liu Dong , Liu Dachuan , Chuang Tsung-Hsien , Xiang Rong , Luo Yunping
Published: April 2023

Supplementary Figure legend
Supplementary Figure S6 from Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells
Authors: Bodogai Monica , Moritoh Kanako , Lee-Chang Catalina , Hollander Christine M. , Sherman-Baust Cheryl A. , Wersto Robert P. , Araki Yoshihiko , Miyoshi Ichiro , Yang Li , Trinchieri Giorgio , Biragyn Arya
Published: April 2023

B cells from in tumor-bearing mice up regulate TGFÎ²ï�¢expression to educate MDSC via TGFÎ² receptor signaling.
Suppl Fig5 from Agr2 Mediates Paracrine Effects on Stromal Fibroblasts That Promote Invasion by Gastric Signet-Ring Carcinoma Cells
Authors: Tsuji Tadahiro , Satoyoshi Rika , Aiba Namiko , Kubo Takanori , Yanagihara Kazuyoshi , Maeda Daichi , Goto Akiteru , Ishikawa Kazuo , Yashiro Masakazu , Tanaka Masamitsu
Published: April 2023

Suppl Fig5. 3D gel-invasion assay using NFs with MKN-74 cells expressing Agr2 mutants.
Supplementary Figure S2 from Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells
Authors: Bodogai Monica , Moritoh Kanako , Lee-Chang Catalina , Hollander Christine M. , Sherman-Baust Cheryl A. , Wersto Robert P. , Araki Yoshihiko , Miyoshi Ichiro , Yang Li , Trinchieri Giorgio , Biragyn Arya
Published: April 2023

MDSC from Î¼MT mice express reduced levels of ROS and Arg1.
Supplementary Figure S1 from Stromal Fibroblasts Induce CCL20 through IL6/C/EBPβ to Support the Recruitment of Th17 Cells during Cervical Cancer Progression
Authors: Walch-Rückheim Barbara , Mavrova Russalina , Henning Melanie , Vicinus Benjamin , Kim Yoo-Jin , Bohle Rainer Maria , Juhasz-Böss Ingolf , Solomayer Erich-Franz , Smola Sigrun
Published: April 2023

Sections of human cervical SCCs were co-stained with the respective isotype control antibodies for CD4 and IL-17 or CCR6 and IL-17 by IF or with the respective isotype control antibody for CCL20 by IHC.
Supplemental Figure Legends from Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors
Authors: An Ningfei , Xiong Ying , LaRue Amanda C. , Kraft Andrew S. , Cen Bo
Published: April 2023

Detailed Legends for All Supplemental Figures
Supplementary Table legend from CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolysis and Enhances Patient Survival
Authors: Ullrich Nico , Heinemann Anja , Nilewski Elena , Scheffrahn Inka , Klode Joachim , Scherag André , Schadendorf Dirk , Singer Bernhard B. , Helfrich Iris
Published: April 2023

Supplementary Table legend. Supplementary Table legends S1, S2
Figure S1 from Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors
Authors: An Ningfei , Xiong Ying , LaRue Amanda C. , Kraft Andrew S. , Cen Bo
Published: April 2023

Inhibition of Pim suppresses PHA665752-resistant colony formation in MET-dependent cells.
Supplementary Figure 1 from CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolysis and Enhances Patient Survival
Authors: Ullrich Nico , Heinemann Anja , Nilewski Elena , Scheffrahn Inka , Klode Joachim , Scherag André , Schadendorf Dirk , Singer Bernhard B. , Helfrich Iris
Published: April 2023

Supplementary Figure 1. CEACAM1-3S modulates melanoma cell sensitivity against NK cell-mediated cytolysis.
Supplementary Figures 1-5 from Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs
Authors: Pandita Raj K. , Chow Tracy T. , Udayakumar Durga , Bain Amanda L. , Cubeddu Liza , Hunt Clayton R. , Shi Wei , Horikoshi Nobuo , Zhao Yong , Wright Woodring E. , Khanna Kum Kum , Shay Jerry W. , Pandita Tej K.
Published: April 2023

Supplementary Figures 1-5. Supplementary Fig. 1. Analysis of single-strand G-overhang by native and denatured DNA gel electrophoresis. Supplementary Fig. 2. Telomere FISH analysis of chromosomal aberrations induced by Ssb1 depletion in mouse and human cells at metaphase. Supplementary Fig. 3. Analysis of hTERT and hSsb1 co-dependent association with telomeres by ChIP. Supplementary Fig. 4. Analysis of hSsb1 interaction with TRF1 and TRF2 by co-immunoprecipitation and ChIP analysis of their influence on hSsb1 recruitment to telomeres. Supplementary Fig. 5. Measurement of in vitro telomerase activity (TRAP assay) in control and hSsb1 depleted cells.
Supplementary Table S1 from PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets
Authors: Scortegagna Marzia , Lau Eric , Zhang Tongwu , Feng Yongmei , Sereduk Chris , Yin Hongwei , De Surya K. , Meeth Katrina , Platt James T. , Langdon Casey G. , Halaban Ruth , Pellecchia Maurizio , Davies Michael A. , Brown Kevin , Stern David F. , Bosenberg Marcus , Ronai Ze'ev A.
Published: April 2023

Supplementary Table S1. RPPA analysis of phosphorylated proteins altered upon PDK1i.
Supplementary Figures S1-S6 from PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets
Authors: Scortegagna Marzia , Lau Eric , Zhang Tongwu , Feng Yongmei , Sereduk Chris , Yin Hongwei , De Surya K. , Meeth Katrina , Platt James T. , Langdon Casey G. , Halaban Ruth , Pellecchia Maurizio , Davies Michael A. , Brown Kevin , Stern David F. , Bosenberg Marcus , Ronai Ze'ev A.
Published: April 2023

Supplementary Figures S1-S6. BrafV600E::Cdkn2a-/- delay development of tumors in PtenWT::Pdk-/-genotype (S1); Inhibition of SGK1 or SGK3 resembles changes in signaling seen upon PDK1 inhibition (S2); SGK and PDK1 inhibition affect cell cycle progression (S3); Synthetic lethal screen for PDK1i combination drugs (S4); RPPA analysis of signaling components that are affected upon inhibition of PDK1 (S5); PDK1 KD reduces the expression of genes involved in pigmentation and metastasis (S6).
Supplementary Figure 5 from eIF4E Threshold Levels Differ in Governing Normal and Neoplastic Expansion of Mammary Stem and Luminal Progenitor Cells
Authors: Avdulov Svetlana , Herrera Jeremy , Smith Karen , Peterson Mark , Gomez-Garcia Jose R. , Beadnell Thomas C. , Schwertfeger Kathryn L. , Benyumov Alexey O. , Manivel J. Carlos , Li Shunan , Bielinsky Anja-Katrin , Yee Douglas , Bitterman Peter B. , Polunovsky Vitaly A.
Published: April 2023

Supplementary Fig. S5. HA-eIF4E rescues HMEC/hTERT cells from Ras-induced senescence and activates ATR signaling.
Supplemental Figure S4 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: April 2023

Supplemental Figure S4. Akti-treated tumor-specific Pmel CD8+ T cell have reduced phosphorylation of Akt and substrates in presence of pharmacologic inhibition of Akt.
Supplemental Figure S3 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: April 2023

Supplemental Figure S3. Surface phenotype of Akti-treated and vehicle TIL isolated from patient with melanoma and expanded to clinical scale for 30 days prior to adoptive-transfer into humanized mouse model.
Supplementary Figure S2 from Constitutive Activation of Myosin-Dependent Contractility Sensitizes Glioma Tumor-Initiating Cells to Mechanical Inputs and Reduces Tissue Invasion
Authors: Wong Sophie Y. , Ulrich Theresa A. , Deleyrolle Loic P. , MacKay Joanna L. , Lin Jung-Ming G. , Martuscello Regina T. , Jundi Musa A. , Reynolds Brent A. , Kumar Sanjay
Published: April 2023

Supplementary Figure S2. BMP4-induced differentiation alters tumor-initiating cell spread area, but not motility.
Supplementary Figure S2 from UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas
Authors: Wong Stephen Q. , Waldeck Kelly , Vergara Ismael A. , Schröder Jan , Madore Jason , Wilmott James S. , Colebatch Andrew J. , De Paoli-Iseppi Ricardo , Li Jason , Lupat Richard , Semple Timothy , Arnau Gisela Mir , Fellowes Andrew , Leonard J. Helen , Hruby George , Mann Graham J. , Thompson John F. , Cullinane Carleen , Johnston Meredith , Shackleton Mark , Sandhu Shahneen , Bowtell David D.L. , Johnstone Ricky W. , Fox Stephen B. , McArthur Grant A. , Papenfuss Anthony T. , Scolyer Richard A. , Gill Anthony J. , Hicks Rodney J. , Tothill Richard W.
Published: April 2023

Western blot analysis of ERK and phosphorylated ERK in the MCC 14, MCC 13 and MCC26 Merkel cell carcinoma lines.
Supplementary Tables S1-S6 from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: April 2023

Distribution of neoplasm types between Control (0 Gy) and irradiated (5.4 Gy) mice (excluding outliers) ; Number of feature samples for various groups at different time intervals within 1 year ; Retention times and m/z ratios of quality controls and their standard errors ; Summary of Random Forest Classification ; Significant features (FDR<4.2%) in Control vs. IR comparison at any one of the four time groups ; Features Correlating with Pattern Matching from IRH, IRB, and IRS Neoplasms .
Supplementary Figure S5 from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: April 2023

Six patterns of relative IRB, IRH and IRS levels considered for template matching.
Supplementary Materials and Methods from Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition
Authors: Herkert Barbara , Kauffmann Audrey , Mollé Sandra , Schnell Christian , Ferrat Thomas , Voshol Hans , Juengert Janina , Erasimus Hélène , Marszalek Grégory , Kazic-Legueux Malika , Billy Eric , Ruddy David , Stump Mark , Guthy Daniel , Ristov Mitko , Calkins Keith , Maira Sauveur-Michel , Sellers William R. , Hofmann Francesco , Hall Michael N. , Brachmann Saskia M.
Published: April 2023

Supplementary materials and methods.
Supplementary Figure S2 from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: April 2023

Comparison of metabolite profiles of 5.4 Gy (IR) to 0 Gy (Control) using 525 samples (Control = 141 from 17 mice, IR = 384 from 51 mice).
Supplementary Figure Legends from Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Authors: Cook John A. , Chandramouli Gadisetti V.R. , Anver Miriam R. , Sowers Anastasia L. , Thetford Angela , Krausz Kristopher W. , Gonzalez Frank J. , Mitchell James B. , Patterson Andrew D.
Published: April 2023

Legend for Supplementary Figures S1-S5.
Supplementary Figure 5 from Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition
Authors: Herkert Barbara , Kauffmann Audrey , Mollé Sandra , Schnell Christian , Ferrat Thomas , Voshol Hans , Juengert Janina , Erasimus Hélène , Marszalek Grégory , Kazic-Legueux Malika , Billy Eric , Ruddy David , Stump Mark , Guthy Daniel , Ristov Mitko , Calkins Keith , Maira Sauveur-Michel , Sellers William R. , Hofmann Francesco , Hall Michael N. , Brachmann Saskia M.
Published: April 2023

MAPK pathway inhibition synergizes with PI3Kβ inhibition in WM-266-4, but not in A-375. A-D) Determination of PI3K/BRAF and PI3K/MEK inhibitor synergy in WM-266-4 (A+B) and A-375 (C+D) using proliferation assays. Dose matrices highlight percentages of proliferation inhibition relative to DMSO with 100 indicating complete block of proliferation and >100 indicative of cell death. SS, synergy score. PI3Kβi1/2=rac-KIN-193/GSK-2636771, panPI3Ki=GDC0941, PI3Kαi=BYL719, BRAFi=LGX818, MEKi=MEK162
Supplementary Figure 3 from Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival
Authors: den Hollander Petra , Rawls Kathryn , Tsimelzon Anna , Shepherd Jonathan , Mazumdar Abhijit , Hill Jamal , Fuqua Suzanne A.W. , Chang Jenny C. , Osborne C. Kent , Hilsenbeck Susan G. , Mills Gordon B. , Brown Powel H.
Published: April 2023

Supp Fig 3 - A-B) Average tumor growth of MDA MB231 shPTP4A3 and control tumors treated with doxycycline or vehicle. C) mRNA expression of MDA MB231 control tumors and PTP4A3 tumors treated with doxycycline or vehicle. D) Average tumor growth of MDA MB468 control tumors and PTP4A3 tumors treated with doxycycline or vehicle. D) Tumor growth rate is not reduced in tumors from the ER-positive breast cancer cell lines.E). Tumor growth slopes of MCF-7 control tumors and PTP4A3 tumors treated with doxycycline or vehicle.
Table S7 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: April 2023

Genes that significantly i) lost H3K27me3 coverage ii) lost DNA methylation iii) gained expression in Be(2)-C and IMR5-75 cells upon combination treatment with DAC and EPZ-6438
Suppl Table 3 from A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells
Authors: Hölzel Michael , Landsberg Jennifer , Glodde Nicole , Bald Tobias , Rogava Meri , Riesenberg Stefanie , Becker Albert , Jönsson Göran , Tüting Thomas
Published: April 2023

Supplementary Table 3. Gene lists of the mouse gene signatures used in this study.
Supplementary Materials and Methods, Figures 1 - 11, Tables 1 - 4 from Lysine Demethylase LSD1 Coordinates Glycolytic and Mitochondrial Metabolism in Hepatocellular Carcinoma Cells
Authors: Sakamoto Akihisa , Hino Shinjiro , Nagaoka Katsuya , Anan Kotaro , Takase Ryuta , Matsumori Haruka , Ojima Hidenori , Kanai Yae , Arita Kazunori , Nakao Mitsuyoshi
Published: April 2023

Supplementary Figure 1. Metabolic alteration in LSD1-inhibited cancer cells. Supplementary Figure 2. Overall view of the metabolomic analysis in LSD1-KD HepG2 cells. Supplementary Figure 3. GSEA results of the microarray experiment in LSD1-KD HepG2 cells. Supplementary Figure 4. Effect of LSD1-KD on energy metabolism in Huh-7, human hepatocellular carcinoma cells. Supplementary Figure 5. Effect of LSD1-KD on the expression of the glucose transporter GLUT1. Supplementary Figure 6. Overexpression of LSD1 in HepG2 cells. Supplementary Figure 7. Effect of LSD1-KD on the expression of metabolic genes in breast cancer cells. Supplementary Figure 8. Distinct expression of LSD1 in hepatocellular carcinoma and normal hepatic cells. Supplementary Figure 9. LSD1 regulates glycolytic genes through the HIF-1a-mediated pathway. Supplementary Figure 10. LSD1 physically interact with HDACs but not with HIF-1a/HIF-1B in HepG2 cells. Supplementary Figure 11. Effect of LSD1 inhibition in mouse xenograft model. Supplementary Table 1. siRNAs target sequences. Supplementary Table 2. Concentrations of the metabolites indicated in Figure 1E. Supplementary Table 3. Full descriptions of the gene abbreviations used in this study. Supplementary Table 4. Primers used in the study.
Supplementary Figures S1-S5 from Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases
Authors: Tanei Tomonori , Leonard Fransisca , Liu Xuewu , Alexander Jenolyn F. , Saito Yuki , Ferrari Mauro , Godin Biana , Yokoi Kenji
Published: April 2023

Dynamic light scattering analysis of nAb-PTX dispersed in water. The mean diameter of the aggregates is 12.4nm ; Gross appearance of breast (4T1) and lung (3LL) liver metastasis following various therapies ; Histological evaluation (H&E) consequently revealed that the tumor diameters at microscopic level in breast (4T1 cells) or lung (3LL cells) liver metastases were significantly smaller in the mice treated with MSV-nAb-PTX as compared to other therapy groups ; Dose response curves of viability of 4T1, 3LL cells, and abdominal macrophages treated with nAb-PTX and MSV-nAb-PTX as determined by MTT and WST-1 assay ; MSV biodistribution in 4T1 primary tumor and liver in the mice pre-treated with/without clodronate liposomes was evaluated by ICP-AES analysis .
Supplementary table 4 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: April 2023

Changes of Cho-containing metabolites upon E2 stimulation
Supplementary Figure 2 from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: April 2023

Supplementary Figure 2. miR-892b expression is downregulated in breast cancer and inversely correlates with breast cancer progression and poor prognosis.
Supplementary table 1 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: April 2023

The core set of direct ERalpha regulated genes in breast cancer cells
Supplemental Table 3 from G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program
Authors: Yim Christina Y. , Sekula David J. , Hever-Jardine Mary P. , Liu Xi , Warzecha Joshua M. , Tam Janice , Freemantle Sarah J. , Dmitrovsky Ethan , Spinella Michael J.
Published: April 2023

Inivariant Cox proportional analysis for replace/recurrence free survival in breast cancer with high G0S2
Supplementary Figures 1 and 2 and Supplementary Table 1 from Enfortumab Vedotin Antibody–Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models
Authors: Challita-Eid Pia M. , Satpayev Daulet , Yang Peng , An Zili , Morrison Karen , Shostak Yuriy , Raitano Arthur , Nadell Rossana , Liu Wendy , Lortie Dawn Ratay , Capo Linnette , Verlinsky Alla , Leavitt Monica , Malik Faisal , Aviña Hector , Guevara Claudia I. , Dinh Nick , Karki Sher , Anand Banmeet S. , Pereira Daniel S. , Joseph Ingrid B.J. , Doñate Fernando , Morrison Kendall , Stover David R.
Published: April 2023

Figure 1: ADC Localization in tumor xenografts Figure 2: PK profile in mice Table 1: Toxicokinetic parameters
Supplementary Table 4 from Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Authors: Osman Abdullah A. , Neskey David M. , Katsonis Panagiotis , Patel Ameeta A. , Ward Alexandra M. , Hsu Teng-Kuei , Hicks Stephanie C. , McDonald Thomas O. , Ow Thomas J. , Alves Marcus Ortega , Pickering Curtis R. , Skinner Heath D. , Zhao Mei , Sturgis Eric M. , Kies Merrill S. , El-Naggar Adel , Perrone Federica , Licitra Lisa , Bossi Paolo , Kimmel Marek , Frederick Mitchell J. , Lichtarge Olivier , Myers Jeffrey N.
Published: April 2023

Supplementary Table 4: Expression of genes associated with loss and gain of function phenotypes for ordinal regression analysis shown in Figure 3B and 3F.