bluuebunny/crossref_metadata_2025 huggingface dataset:
New Platinum (II) Ternary Complexes of Formamidine and Pyrophosphate: Synthesis, Characterization and DFT Calculations and In vitro Cytotoxicity
Authors: Soliman Ahmed A. , Attaby Fawzy A. , Alajrawy Othman I. , Abou-hussein Azza A.A. , Linert Wolfgang
Published: February 2020

Aim and Objective:

Platinum (II) and platinum (IV) of pyrophosphate complexes have been prepared and characterized to discover their potential as antitumor drugs. This study was conducted to prepare and characterize new ternary platinum (II) complexes with formamidine and pyrophosphate as an antitumor candidate.

Materials and Methods:

The complexes have been characterized by mass, infrared, UV-Vis. spectroscopy, elemental analysis, magnetic susceptibility, thermal analyses, and theoretical calculations. They have been tested for their cytotoxicity, which was carried out using the fastcolorimetric assay for cellular growth and survival against MCF-7 (breast cancer cell line), HCT- 116 (colon carcinoma cell line), and HepG-2 (hepatocellular cancer cell line).

Results:

All complexes are diamagnetic, and the electronic spectral data displayed the bands due to square planar Pt(II) complexes. The optimized complexes structures (1-4) indicated a distorted square planar geometry where O-Pt-O and N-Pt-N bond angles were 82.04°-96.44°, respectively.

Conclusion:

The complexes showed noticeable cytotoxicity and are considered as promising antitumor candidates for further applications.
Jurisprudence Study of the Importance of the Role of a Woman’s Right to Have a Child: A Review
Authors: Ghodrati Fatemeh
Published: February 2020

Background:

Every woman has the right to have children.

Objective:

This study aimed to investigate the Jurisprudence study of the importance of the role of a
woman right to have a child.

Methods:

A review of the literature with keywords of motherhood. The viewpoints of the jurists,
jurisprudent law, right contraception and breastfeeding, spiritual rewards, pregnant women, instinct
of having a child and the Quran. The Information Centers such as Scopus and Iranmedex, Magi ran
SID, Google Scholar, Science Direct, Pub med, and in the returns without any time limitations up to
2018. Therefore, Qur'anic verses based on the topic and authentic Hadith texts as well as authoritative,
authentic scientific articles.

Results:

Narrations and Quran verses on greatness and respect of a mother show the importance of
the maternal role. The maternal role is a fabulous facet of perfection of a woman and Islam has
considered spiritual rewards for it. In the Quran, many biological changes such as pregnancy, childbirth,
breastfeeding and taking care of a child and spiritual characteristics of mothers as the instinct
seeking a child or generosity towards child have been mentioned. Islamic rules have a duty to extend
this culture and aid mothers to achieve this right. Nobody can deprive a woman of it.

Conclusion:

In view of jurisprudent rules in Islam, if there is no limitation or natural barrier for a
woman to have a child but her husband’s illogical unwillingness for having a child; this is, according
to article 1130 of civil law, a kind of distress and embarrassment and the woman has the right to
divorce.
Relative Estimate of Revised Cardiovascular Risk Combining Traditional and Non-traditional Image-based CV Markers: A Kerala Based Study
Authors: Paul Paulin , George Noel , Shan B. Priestly
Published: February 2020

Background:

Non-traditional image markers can improve the traditional cardiovascular
risk estimation, is untested in Kerala based participants.

Objective:

To identify the relationship between the ‘Modified CV risk’ categories with traditional
and non-traditional image-based risk markers. The correlation and improvement in reclassification,
achieved by pooling atherosclerotic non-traditional markers with Intermediate (≥7.5% and <20%)
and High (≥20%) 10-year participants is evaluated.

Methods:

The cross-sectional study with 594 participants has the ultrasound measurements recorded
from the medical archives of clinical locations at Ernakulum district, Kerala. With carotid
Intima-Media Thickness (cIMT) measurement, the Plaque (cP) complexity was computed using
selected plaque characteristics to compute the carotid Total Plaque Risk Score (cTPRS) for superior
risk tagging. Statistical analysis was done using RStudio, the classification accuracy was verified
using the decision tree algorithm.

Results:

The mean age of the participants was (58.14±10.05) years. The mean cIMT was
(0.956±0.302) mm, with 65.6% plaque incidence. With 94.90% variability around its mean, the
Multinomial Logistic Regression model identifies cIMT and cTPRS, age, diabetics, Familial Hypercholesterolemia
(FH), Hypertension treatment, the presence of Rheumatoid Arthritis (RA),
Chronic Kidney Disease (CKD) as significant (p<0.05). cIMT and cP were found significant for
‘Intermediate High’, ‘High’ and ‘Very High’ ‘Modified CV risk’ categories. However, age, diabetes,
gender and use of hypertension treatment are significant for the ‘Intermediate’ ‘Modified CV
risk’ category. The overall performance of the MLR model was 80.5%. The classification accuracy
verified using the decision tree algorithm has 78.7% accuracy.

Conclusion:

The use of atherosclerotic markers shows a significant correlation suitable for a nextlevel
reclassification of the traditional CV risk.
Chemical Composition and Bioactivity of Essential Oil and Extracts of Salvia limbata C.A. Mey (Lamiaceae)
Authors: Mahdavi Behnam , Ghezi Somaye , Maleki Behroz
Published: February 2020

Background:

This research tried to evaluate the chemical composition of the essential oil of
Salvia limbata, and also bioactivity of essential oil and the plant extract. S. limbata is an aromatic plant
with medicinal uses, such as analgesic, anti-inflammatory activities.

Methods:

The essential oils of the flowers of Salvia limbata were obtained using a Clevenger-type apparatus,
and its chemical composition was identified by chromatography methods. The study was also conducted
to evaluate antioxidant and antibacterial activities of the plant extracts. For this purpose, the leaves
and flowers of S. limbata were extracted using methanol and then fractioned by n-hexane and Ethyl Acetate
(EtOAc). Total Phenolic Content (TPC), Total Flavonoid Content (TFC), Radical Scavenging Activity
(RSA) and the Disc-Diffusion (DD) assay were run to study the bioactivity of the plant extracts.

Results:

The oil was dominated by the oxygenated hydrocarbon of 5-methylene-2,3,4,4-tetramethylcyclopent-
2-enone (37.1%), oxygenated sesquiterpene of occidol (22.8%), and sesquiterpene hydrocarbon
of β-bourbonene (12.1%). The EtOAc extract of the flowers showed the TPC with 66.2±0.62 mg
GAE/g (mg of gallic acid equivalents per gram of extract) and RSA with IC50 of 17.96±0.54 μg/mL.
Although the EtOAc extract of the leaves exhibited the highest TFC with 61.96±4.73 mg RuE/g (mg of
rutin equivalents per gram of extract). The extracts inhibited the growth of Escherichia coli, Citrobacter
frurdi, Pseudomonas aeruginosa, and Streptococcus pneumonia. The extracts were inactive against
Staphylococcus coagulase, Enterobacter aerogenes, Acinetobacter baumannii, Serratia marcescens,
and Klebsiella pneumoni.

Conclusion:

According to the results, the plant extracts were potent agant in antioxidant activity.
Role of Cytochrome P450 in Prostate Cancer and its Therapy
Authors: Kaushik Rishabh , Khan Sheeza , Sharma Meesha , Hemalatha Srinivasan , Mueed Zeba , Poddar Nitesh K.
Published: February 2020

Prostate cancer has become a global health concern as it is one of the leading causes of mortality in males. With the emerging drug resistance to conventional therapies, it is imperative to unravel new molecular targets for disease prevention. Cytochrome P450 (P450s or CYPs) represents a unique class of mixed-function oxidases which catalyses a wide array of biosynthetic and metabolic functions including steroidogenesis and cholesterol metabolism. Several studies have reported the overexpression of the genes encoding CYPs in prostate cancer cells and how they can be used as molecular targets for drug discovery. But due to functional redundancy and overlapping expression of CYPs in several other metabolic pathways there are several impediments in the clinical efficacy of the novel drugs reported till now. Here we review the most crucial P450 enzymes which are involved in prostate cancer and how they can be used as molecular targets for drug discovery along with the clinical limitations of the currently existing CYP inhibitors.
The Effect of p53-R249S on the Suppression of Hepatocellular Carcinoma Cells Survival Induced by Podophyllum Derivatives
Authors: Chen Huan , Zhang Mingyang , Wang Ziping , Li Lingqi , Li Qiqi , Wang Huai
Published: February 2020

Background:

Hepatocellular Carcinoma (HCC), the second leading cause of cancer-related mortality
with over half a million new cases diagnosed annually in the world, accounts for nearly 70% of cancer deaths in
parts of Asia and Africa. Podophyllum, one of the important members of the lignane class of natural products
derived from plants in Podophyllum peltatum L., has been shown to suppress tumor growth in various cancers.
However, the effects of Podophyllum compounds on HCC and the mechanisms for its tumor-suppressive function
remain unknown.

Methods:

A molecular docking study was employed to the analysis of the interaction between compounds and
their targeted proteins. Cell proliferation was measured by MTT assay. Western blot analysis was used to evaluate
protein expression. qRT-PCR was performed to assess RNA expression.

Results:

Molecular docking analysis was consistent with the beneficial effect of fluorine atom substituent in the
3-position of 2-aminopyridine in our previous study. Also, P-3F and D-3F displayed the most potent cytotoxicities
against PLC/PRF/5 with p53-R249S and weakest inhibition of L02 (normal liver cell) growth. However,
these derivatives had no effect on the suppression of HepG2 (wild-type p53) and Hep3B (p53-null) proliferation
significantly. Further study showed that both compounds increase γ-H2AX expression in PLC/PRF/5 cell, along
with repression of the c-Myc activation, purportedly by induction of p53 level and transcriptional activation.

Conclusion:

The results suggested that podophyllum derivatives containing fluorine atom in the 3-position of 2-
aminopyridine could inhibit the growth of HCC harboring p53-R249S by restoring the activity of p53 with decreasing
the level of c-Myc.
Advantages of Contour Crafting in Construction Applications
Authors: Akhnoukh Amin K.
Published: February 2020

Contour crafting application has been widely used in different industrial, pharmaceutical,
medical, and aviation applications for more than three decades. Recently, mega-sized 3-D
printers were developed, with sufficient capability to print full-scale construction projects, including
walls, homes, bridges, and multi-story buildings. Successful 3-D printing of projects is accomplished
by the Additive Manufacturing (AM) process through the placement of successive layers of
construction materials using robotic arms (3-D printers). This layered construction, known as contour
crafting, is controlled by computer modeling software. This paper presents the history of contour
crafting development, its current application in construction, the advantages of contour crafting
applications in construction, and the main impediments to the widespread of contour crafting in
the local construction market. In addition, this paper highlights the current research efforts made to
integrate Building Information Modeling (BIM) in contour crafting construction. Based on the recent
research findings, contour crafting application in construction improves job site productivity
and project sustainability as a result of reduced material waste in construction sites. Finally, the automated
construction through the application of contour crafting technique results in improved job
site safety and increased overall quality of construction projects due to the increased automation in
construction.
Factors Affecting Sustainability Performance during the Construction Stage in Building Projects-Consultants’ Perspective
Authors: Tayeh Bassam A. , Abu Aisheh Yazan I. , Abuzuhri Ibrahim O.
Published: February 2020

Background:

The construction industry significantly contributes towards enriching human inhabitation within the built environment. However, the industry generates one-third of the world’s carbon emissions per annum (a major contributor to climate change). In response, a sustainable construction development agenda has been propagated by governments worldwide.

Objective:

This research investigates the factors affecting sustainability performance during the construction stage of building projects in the Gaza Strip from consultants’ viewpoint.

Methods:

A questionnaire was distributed to 35 consultants, and 31 completed questionnaires were returned, representing a response rate of 88.57%. A total of 55 variables were considered in this study and listed within three thematic factor groups, namely, economic, social and environmental factors. Data collected were analysed using factor analysis and relative important index within the Statistical Package for the Social Sciences (v22).

Results:

Results indicated that the most influential factors are i) Economic: professional fees of engineers and consultants, energy cost and use of full equipment capacity; ii) Social: availability of knowledge and skills in the labour force, increased burden on infrastructure as a result of the use and depletion of natural resources and public awareness; and iii) Environmental: environmental regulations, pollution generation and waste generation.

Conclusion:

Lack of awareness about economic and social sustainability was found due to the traditional definition of environmental
sustainability and the upper and indirect super-vision of consultants to the construction stage.
THE EFFECTS OF PROBLEM-BASED LEARNING METHOD ON STUDENTS’ LEARNING INDEPENDENCE OF CHEMISTRY LEARNING IN HIGH SCHOOL
Authors: Suyanta Suyanta , Laksono Endang W. , Fadhilah Novia Fitri , Rizky Ihwan
Published: February 2020

Chemistry learning in high school that trains and develops students’ self-sufficiency and independence has not been done optimally because learners still depend on getting information and knowledge from teachers. Problem-based learning method used in the teaching and learning process is expected to facilitate students’ with self-reliance and learning independence. This method is a problem-oriented learning method that makes students be accustomed to solving problems in order to train their ability in discoveringa concept in the learning process. Teaching learning process with PBL model is done for the subject matter of acid & base solution and electrolyte & non electrolyte solution. Learning independence assessed in this study were self-management, motivation, and confidence. The data of the study were in the form of descriptive quantitative data and analyzed using Anava / Anacova test. The research findings showed that there was a difference of students’ learning independence through the application of problem-based learning method and control method in teaching and learning process.
THE EFFECTIVENESS OF MULTIPLE INTELLIGENCES BASED COLLABORATIVE PROBLEM SOLVING TO IMPROVE CRITICAL THINKING
Authors: Winarti Atiek , Rahmini Ani , Almubarak Almubarak
Published: February 2020

KEEFEKTIFAN COLLABORATIVE PROBLEM SOLVING BERBASIS MULTIPLE INTELLIGENCES UNTUK MENINGKATKAN KETERAMPILAN BERPIKIR KRITISAbstrakPenelitian ini bertujuan mengetahui keefektifan strategi Collaborative Problem Solving berbasis Multiple Intelligences (CPS-MI) dalam meningkatkan keterampilan berpikir kritis, kecerdasan logis matematis, dan penguasaan konsep kimia peserta didik, serta mengetahui hubungan antara berpikir kritis, kecerdasan logis matematis dengan penguasaan konsep kimia. Metode penelitian menggunakan desain pre-test-post test control group. Sampel terdiri atas 93 peserta didik kelompok eksperimen dan 90 peserta didik kelompok kontrol dari tiga SMA di Kota Banjarmasin yang dipilih melalui metode stratified random sampling. Kelompok eksperimen menerapkan strategi CPS-MI, sedangkan kelompok kontrol menerapkan pembelajaran konvensional. Instrumen penelitian menggunakan Watson Glaser Critical Thinking Appraisal Test, angket multiple intelligences, lembar observasi, dan tes penguasaan konsep Hidrolisis garam. Data penelitian dianalisis menggunakan teknik persentase, chi square test, Anava satu jalur, dan uji korelasi ganda. Hasil penelitian menunjukkan bahwa strategi CPS-MI efektif dalam meningkatkan keterampilan berpikir kritis, kecerdasan logis matematis dan penguasaan konsep kimia. Berdasarkan temuan ini strategi CPS-MI efektif diterapkan sebagai alternatif meningkatkan keterampilan berpikir kritis dan kecerdasan logis matematis peserta didik. AbstractThis study was aimed at determining the effectiveness of Multiple Intelligences based Collaborative Problem-Solving (MI-CPS) strategy in improving students' critical thinking skills, mathematical logical intelligence, and chemical concept mastery, as well as knowing the relationship between critical thinking, mathematical logical intelligence, and chemical concept mastery. The study used a pretest-posttest control group design. The sample consisted of 93 experimental group students and 90 control group students from three high schools in Banjarmasin. The samples were selected through a stratified random sampling method. The experimental group applied the MI-CPS strategy, while the control group applied conventional learning. The instruments used were Watson Glaser Critical Thinking Appraisal Test, multiple intelligences questionnaire, observation sheet, and mastery test concept of salt hydrolysis. The research data were analyzed using percentage techniques, chi-square test, one-way ANAVA, and multiple correlation tests. The results show that the MI-CPS strategy is effective in improving critical thinking skills, mathematical logical intelligence, and mastery of chemical concepts. Based on these findings, the MI-CPS strategy is effectively applied as an alternative to improving students' critical thinking skills and mathematical logical intelligence.
THE EFFECTIVENESS OF THE POWER OF TWO STRATEGY ON CRITICAL THINKING SKILLS HIGH SCHOOL STUDENT
Authors: Putri Riana , Ghufron Anik
Published: February 2020

KEEFEKTIFAN STRATEGI THE POWER OF TWO TERHADAP KECAKAPAN CRITICAL THINKING SISWAAbstrakPenelitian ini bertujuan untuk menguji efektivitas strategi the power of two terhadap kecakapan critical thinking. Penelitian ini adalah penelitian quasi-experimental design. Penelitian dilaksanakan di sekolah dengan kemampuan level tinggi, sedang, dan rendah di daerah Kabupaten Bantul Yogyakarta pada Semester Genap Tahun Ajaran 2018/2019. Sampel kelas dipilih dengan menggunakan teknik random sampling terpilih 2 kelas pada masing-masing sekolah. Data yang dikumpulkan adalah data tes kecakapan critical thinking. Data dianalisis melalui uji independent sampel t-test dan uji Anova. Hasil penelitian menunjukkan pembelajaran dengan menggunakan strategi the power of two lebih efektif daripada menggunakan strategi ekspositori terhadap kecakapan critical thinking siswa SMA Kelas XI MIPA, terdapat perbedaan kecakapan critical thinking pembelajaran yang menggunakan strategi the power of two dan pembelajaran yang menggunakan strategi ekspositori terhadap kecakapan critical thinking pada sekolah dengan level tinggi, sedang, dan rendah, dan ada interaksi antara penggunaan strategi the power of two dan sekolah dengan level tinggi, sedang, dan rendah terhadap kecakapan critical thinking peserta didik.Kata kunci: the power of two, critical thinking, strategi ekspositoriAbstractThis study was aimed at examining the effectiveness of the power of two strategy on critical thinking skills. This research was chategorized as a quasi-experimental design research. The study was conducted in high, medium and low-level schools in Yogyakarta in the even semester of the 2018/2019 school year. Class samples were selected using a random sampling technique, then 2 classes were selected in each school. The data collected were critical thinking skills test data. There data then analyzed through independent sample t-test and ANOVA test. The results show that the power of two strategy was more effective than using expository strategies for the critical thinking skills of high school students. There were differences in critical thinking learning skills using the power of two strategy and expository strategy for critical thinking skills in schools with high, medium, and low levels. There is also an interaction between the use of the power of two strategy towards the students' critical thinking skills.
FAKTOR-FAKTOR PEMBENTUKAN DAERAH OTONOMI BARU DAN DAMPAKNYA TERHADAP KEUANGAN NEGARA
Authors: Maulana Arief
Published: February 2020

The reformation of the Government of the Republic of Indonesia system, which was marked by the change from centralized to decentralized system, had an impact on the trend of regional expansion. But, from the end of 2014 the government implemented a moratorium on the formation of new autonomous regions with the reason to focus on resolving the problem of the size of the budget deficit before lifting the moratorium. The purpose of this study is to analyze the driving factors of the formation of new autonomous regions in Indonesia during the reformation era and its impact on state finance. This study is a policy study by collecting data and then analyzing it into a conclusion and recommendation. This type of study is a literature study with the method used is descriptive qualitative method. The results of the study show that since the reform era, the formation of a new autonomous region has been very massive. If calculated on average from 1999 to 2014, each year the new regions increase by 13 regions per year. The formation of the new autonomous regions requires considerable preparation and costs, starting from the initial formation to the implementation. In addition, in general the new autonomous regions show higher fiscal dependencies than the old regions. Thus, it can be stated that the establishment of the new autonomous regions has caused pressure on the state finances due to the large amount of funds that must be transferred to new regions.
THE IDENTIFICATION OF SECONDARY METABOLITE COMPOUNDS FROM ETHYL ACETATE FRACTION OF Dendropthoe falcata
Authors: Lestari Astuti , Atun Sri
Published: February 2020

This study was aimed at identifying secondary metabolites of ethyl acetate fraction of Dendrophtoe falcata (L.f.) Ettingsh mindi plant parasite (Melia azedarach L.). This research was conducted by maceration method using ethanol solvent, partitioning sequentially with n-hexane, chloroform, and ethyl acetate. Ethyl acetate fraction was separated by gravity column chromatography (GCC) in two stages. Phase I GCC used n-hexane : ethyl acetate (9 : 1). Phase II GCC used chloroform : methanol (9 : 1) eluent to obtain one pure compound. Purity identification used thin layer chromatography. Characterization of pure compounds obtained was carried out using UV-Vis and IR. The results show that the isolated compounds maximum wavelengths are at 351.20, 262.60, and 207.20 nm which corresponded to the conjugated synamoyl, benzoyl and chromophore phenol. IR spectrum data shows the presence of O-H, C-H aliphatic, C = O carbonyl, C = C aromatic, and C-O. From these data, the isolated compounds show flavonoid type flavanols.IDENTIFIKASI SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT BATANG Dendropthoe falcata.Penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder dari fraksi etil asetat batang Dendrophtoe falcata (L.f.) Ettingsh parasit tumbuhan mindi (Melia azedarach L.). Penelitian ini dilakukan dengan metode maserasi menggunakan pelarut etanol, partisi secara berurutan dengan n-heksana, kloroform, dan etil asetat. Fraksi etil asetat dipisahkan secara kromatografi kolom gravitasi (KKG) dalam dua tahap. KKG tahap I menggunakan eluen n-heksana : etil asetat (9 : 1). KKG tahap II menggunakan eluen kloroform : metanol (9 : 1) sehingga diperoleh satu senyawa murni. Identifikasi kemurnian menggunakan kromatografi lapis tipis. Karakterisasi senyawa murni yang diperoleh dilakukan menggunakan UV-Vis dan IR. Berdasarkan hasil analisis dengan spektrofotometer UV-Vis, senyawa hasil isolasi menunjukkan panjang gelombang maksimum pada 351,20; 262,60; dan 207,20 nm yang sesuai dengan gugus sinamoil, benzoil, dan kromofor fenol terkonjugasi. Data spektrum IR menunjukkan adanya ikatan O-H, C-H alifatik, C=O karbonil, C=C aromatik, dan C-O. Dari data tersebut, senyawa hasil isolasi menunjukkan golongan flavonoid jenis flavonol.
Content Analysis of Apps for Growth Monitoring and Growth Hormone Treatment: Systematic Search in the Android App Store
Authors: Fernandez-Luque Luis , Labarta José I , Palmer Ella , Koledova Ekaterina
Published: February 2020

Background

The use of mobile apps for health is growing. This rapid growth in the number of health apps can make it hard to assess their quality and features. The increased demand for and availability of mobile health apps highlights the importance of regular publication of reviews to identify potential areas of unmet needs and concern. The focus of this review is mobile apps for monitoring growth for health care professionals, caregivers, and patients. Monitoring growth as a part of healthy physical development is important across different periods of childhood and adolescence.

Objective

The goal of this content analysis is to map and understand the types of apps that currently exist that are related to growth monitoring and growth hormone treatment.

Methods

A semiautomated search was undertaken using the app search engine 42Matters, complemented by a manual search for growth apps using the web search tool of Google Play (Android App Store). Apps were rated on their relevance to growth monitoring and categorized by independent raters.

Results

In total, 76 apps were rated relevant to growth monitoring or growth hormone treatment. The level of agreement was measured for the semiautomated search and was very high (Κ=0.97). The target audience for 87% of the apps (66/76) was patients and relatives, followed by health care professionals (11%; 8/76) and both (3%; 2/76). Apps in the category “growth tracking tools for children and babies” were retrieved most often (46%; 35/76) followed by “general baby care apps” (32%; 24/76), “nonpharmacological solutions for growth” (12%; 9/76) and “growth hormone–related” (11%; 8/76). Overall, 19/76 apps (25%) tracked a precise location.

Conclusions

This study mapped the type of apps currently available for growth monitoring or growth hormone treatment that can be used as a foundation for more detailed evaluations of app quality. The popularity of care apps for children and growth monitoring apps should provide a great channel for potential intervention in childhood health in the future.
Text Message Behavioral Intervention for Teens on Eating, Physical Activity and Social Wellbeing (TEXTBITES): Protocol for a Randomized Controlled Trial
Authors: Partridge Stephanie R , Raeside Rebecca , Singleton Anna C , Hyun Karice , Latham Zoe , Grunseit Alicia , Steinbeck Katharine , Chow Clara , Redfern Julie
Published: February 2020

Background

Obesity is among the most significant health challenges facing today’s adolescents. Weight gain during adolescence is related to cardiovascular disease, type 2 diabetes, and some cancers in later life. Presently, adolescents living in Australia have limited access to age-appropriate obesity prevention services.

Objective

This study aims to investigate whether a two-way text message program, with optional telephone health counseling, improves body mass index (BMI) z score and lifestyle outcomes in adolescents who are overweight.

Methods

This study will be a single-blind randomized controlled trial (N=150) comparing a two-way text message intervention, with optional telephone health counseling, to usual care in adolescents (13-18 years old, inclusive) who are overweight (recruited from a pediatric weight management clinic and the broader community in Sydney, Australia). The intervention group will receive a six-month text message program, which consists of two-way, semipersonalized, lifestyle-focused text messages (four messages/week) in addition to usual care. The control group will be assigned to receive usual care. The study also includes a follow-up at 12-months. The primary outcome is a change in BMI z score at six months. Secondary outcomes are changes in waist-to-height ratio, diet, physical and sedentary activity levels, sleep quality, quality of life, self-esteem, self-efficacy, social support, and eating disorder and depression symptoms. Also, we will examine acceptability, utility, and engagement with the program through a study-specific process evaluation questionnaire, semi-structured telephone interviews, and an analysis of health counselor communication logs. The analyses will be performed by the intention-to-treat principle to assess differences between intervention and control groups.

Results

The study opened for recruitment in December 2019. Data collection is expected to be completed by December 2021, and the results for the primary outcome are expected to be published in early 2022.

Conclusions

This study will test the effectiveness of an interactive two-way text message program compared to usual care in improving BMI z score and lifestyle outcomes in adolescents with overweight. This interactive, innovative, and scalable project also aims to inform future practice and community initiatives to promote obesity prevention behaviors for adolescents.

Trial Registration

Australia New Zealand Clinical Trials Registry (ANZCTR) ACTRN12619000389101; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377158&isReview=true

International Registered Report Identifier (IRRID)

DERR1-10.2196/16481
Effectiveness of Electronic Health Interventions in Improving Treatment Adherence for Adults With Obstructive Sleep Apnea: Meta-Analytic Review
Authors: Aardoom Jiska Joëlle , Loheide-Niesmann Lisa , Ossebaard Hans C , Riper Heleen
Published: February 2020

Background

Poor adherence to continuous positive airway pressure (CPAP) treatment by adults with obstructive sleep apnea (OSA) is a common issue. Strategies delivered by means of information and communication technologies (ie, electronic health [eHealth]) can address treatment adherence through patient education, real-time monitoring of apnea symptoms and CPAP adherence in daily life, self-management, and early identification and subsequent intervention when device or treatment problems arise. However, the effectiveness of available eHealth technologies in improving CPAP adherence has not yet been systematically studied.

Objective

This meta-analytic review was designed to investigate the effectiveness of a broad range of eHealth interventions in improving CPAP treatment adherence.

Methods

We conducted a systematic literature search of the databases of Cochrane Library, PsycINFO, PubMed, and Embase to identify relevant randomized controlled trials in adult OSA populations. The risk of bias in included studies was examined using seven items of the Cochrane Collaboration risk-of-bias tool. The meta-analysis was conducted with comprehensive meta-analysis software that computed differences in mean postintervention adherence (MD), which was defined as the average number of nightly hours of CPAP use.

Results

The meta-analysis ultimately included 18 studies (N=5429 adults with OSA) comprising 22 comparisons between experimental and control conditions. Postintervention data were assessed at 1 to 6 months after baseline, depending on the length of the experimental intervention. eHealth interventions increased the average nightly use of CPAP in hours as compared with care as usual (MD=0.54, 95% CI 0.29-0.79). Subgroup analyses did not reveal significant differences in effects between studies that used eHealth as an add-on or as a replacement to care as usual (P=.95), between studies that assessed stand-alone eHealth and blended strategies combining eHealth with face-to-face care (P=.23), or between studies of fully automated interventions and guided eHealth interventions (P=.83). Evidence for the long-term follow-up effectiveness of eHealth adherence interventions remains undecided owing to a scarcity of available studies and their mixed results.

Conclusions

eHealth interventions for adults with OSA can improve adherence to CPAP in the initial months after the start of treatment, increasing the mean nightly duration of use by about half an hour. Uncertainty still exists regarding the timing, duration, intensity, and specific types of eHealth interventions that could be most effectively implemented by health care providers.
Status of AI-enabled Clinical Decision Support Systems Clinical Implementations in China: Cross-sectional Survey (Preprint)
Authors: Ji Mengting , Chen Xiaoyun , Genchev Georgi Z. , Xu Ting , Wei Mingyue , Yu Guangjun
Published: February 2020

BACKGROUND

AI-enabled Clinical Decision Support Systems (AI+CDSSs) were heralded to contribute greatly to the advancement of healthcare services. At present, there is an increased availability of monetary funds and technical expertise invested in projects and proposals targeting the building and implementation of such systems. Therefore, in this context of large funds and technical devotion, understanding the actual system implementation status in clinical practice is imperative.

OBJECTIVE

To understand: 1) the current clinical implementations of AI+CDSSs in Chinese hospitals and 2) concerns regarding AI+CDSSs current and future implementations.

METHODS

A survey supported by the China Digital Medicine journal was performed. We employed stratified cluster sampling and investigated tertiary hospitals from 6 provinces and province-level cities. Descriptive analysis, two-sided Fisher exact test, and Mann-Whitney U-test were utilized for analysis.

RESULTS

Responses were collected from 160 respondents. The analyzable response rate was 86.96%. Thirty-eight of the surveyed hospitals (23.75%) had implemented AI+CDSSs. There were statistical differences on grade, scales, and medical volume between the two groups of hospitals (implemented vs. not-implemented AI+CDSSs, p<0.05). On the 5-point Likert scale, 81.58% (31/38) of respondents rated their overall satisfaction with the systems as 3 to 4. The three most-common concerns were system functions improvement and integration into the clinical process, data quality and data sharing mechanism improvement, and methodological bias.

CONCLUSIONS

While AI+CDSSs were not yet wide-spread in Chinese clinical settings, clinical professionals recognize the potential benefits and challenges regarding in-hospital AI+CDSSs.
DOES HEURISTIC BEHAVIOR LEAVE ANOMALIES IN THE CAPITAL MARKET?
Authors: Asri, M.B.A., Ph.D. Prof. Marwan
Published: February 2020

Introduction/Main Objectives: This study aims to examine the role of heuristics behavior towards the formation of fundamental and technical anomalies in the capital market. Besides, this study also aims to examine the role of fundamental and technical anomalies on investment performance. Background Problems: EMH is not always able to explain all events or phenomena so that it still raises questions and gives results from research that do not meet the expectations, and in the end, this phenomenon is categorized as a market anomaly. This study investigates whether heuristics have an effect on fundamental and technical anomalies and whether the anomalies have an effect on investment performance. Novelty: There is no research that uses hindsight variables incorporated into heuristics; therefore, this study confirms that the indicators used in hindsight measurements are appropriate for measuring what will be measured. Previous research did not involve hindsight in the heuristic category. Research Methods: Data management is done by using SEM with the help of the Warp-PLS analysis tool. Mediation exploration testing with the VAF (Variance Accounted For). Findings/Results: The results of the study show that heuristics (availability, representativeness, and hindsight) are proven to be one of the factors that cause fundamental and technical anomalies in the capital market except for availability heuristics. Conclusion: A large number of anomalies in the capital market do not stop investors from continuing to invest so that at a certain level of investors are satisfied with their investment performance because they use heuristics in an efficient way.
Pengaruh intensi, pengalaman menggunakan internet, kondisi pemfasilitasan, dan undang undang informasi & transaksi elektronik No. 11/2008 terhadap cybercrime
Authors: Anwar Achmad Syaiful Hidayat
Published: February 2020

The aims of this research is to test the influence of intension, experience using the internet, facilitating conditions and undang-undang Informasi & Transaksi Elektronik (ITE) No. 11/2008 on cybercrime. This research uses survey methods. Cluster sampling and purposive sampling method are used to determine research sample. The respondents are internet users who use the internet at warnet and are located in Yogya- karta, Surabaya and Malang. Some 300 questionnaires have been distributed and received back. A total of 291 questionnaires revealed to be analyzed by using multiple regression analysis. Based on the analysis results can be concluded that intention, experience using the Internet, facilitating conditions and UU ITE No. 11/2008 positively influence the occurrence of cybercrime. For further research, it is advisable to increase research variables also affect the occurrence of cybercrime, among others, and increase the number of samples. It aims to obtain research results more representative so that results can be generalized. Keywords: cybercrime, internet, UU ITE No. 11/2008
Remarrying ‘the rational’ to ‘the myth’: an investigation by using baudrillard’s order of simulacra
Authors: Kamayanti Ari
Published: February 2020

In the postmodern era, all things are in the process of changing from sign to simulacrum. This process is called simulation. Accounting and religions are, without exclusion, also in the process of simulation. Debates on how accounting relates to religion have been going on, probably since the claim of Weber’s Ethics of Protestants and The Spirit of Capitalism. Accounting is based on rationalism, while religion that is based on intangible faith and beliefs is regarded as myth. The question is: can the two opposites be combined? This paper tries to provide other alternatives views how accounting relates to religion and how this relation also undergoes simulation. The religion views portrayed are Catholics, Protestants, Buddha and Islam. The methodology used is Baudrillard’s Order of Simulacra as it contains genealogical analysis, such as that put forward by Michel Foucault. The findings, based on literature studies and empirical evidences found in religious institutions websites, confirm that there is a trend of the return of the religion in accounting: a remarrying process in this postmodern era, after it has been divorced during the enlightenment era (Auckflaruung). However, this remarrying process only happens at superficial level, exposing the fact that secularism happens in the religious institutions websites being studied, including Islam. Keywords: Accounting, Religion, Simulacra, Simulation.
The Accountant Perceptions of The IFRS Convergence Plan In Indonesia
Authors: Wahyuni Ersa Tri
Published: February 2020

The Indonesian Institute of Accountants (Ikatan Akuntan Indonesia or IAI), on 23 December 2008, announced that the convergence of local standard to the international accounting standard (IFRS) should be completed by 2012. Indonesia as one of member of the Group of Twenty (G-20) should strive to achieve IFRS compliance as it is one of G-20 goal and commitment in enhancing economic cooperation around the world. This study aims to examine Indonesian accountant perceptions regarding IFRS convergence in 2012. This study is based on a survey which focuses on accountant perceptions in Indonesia. The total population in this study was 275 accountants and auditors who attended the four accounting events in Jakarta held by IAI and IAPI. There was a total sample of 143 respondents, 76 accountants from companies and 67 auditors from public accounting firms. The research revealed many interesting findings. Overall the perception toward the IFRS convergence is positive with 72% respondents has a positive perception and 6.3% respondents have strong positive perception. Language issue in understanding PSAK (a translation from IFRS) is perceived as a problem more to the accountants work in companies rather than accounting firms. However both types of accountants view IFRS training to staffs as an important issue for IFRS implementation in Indonesia. With regard to the advantages of IFRS implementation in Indonesia, the foreign-affiliated institutions voiced higher agreement that IFRS will result in greater comparability of financial performance. They are also confident that Indonesia is ready for IFRS convergence by 2012 in contrast with non-affiliated institutions. And lastly accountants with 0-5 years experience group expressed greater concerns towards Indonesia’s readiness for IFRS implementation as compared to accountants with more than 15 years experience. However overall perception shows that accounting professionals surveyed has positive perceptions towards IFRS convergence in Indonesia Keywords: IFRS Convergence, Implementation, Accountants perception
Pengaruh Informasi Akuntansi Terhadap Kinerja Manajerial dengan Tiga Variabel Moderating (Studi Empiris Pada BPR di Kabupaten Bogor)
Authors: Primasari Dona , Mutmainah Isbandriyati
Published: February 2020

This research is based on the importance of accounting information to the manager’s performance evaluation, which is moderated with environment uncertainty, task uncertainty, and business strategy. It was used the population of Bank Perkreditan Rakyat on Kabupaten Banyumas. The influence of accounting information to managerial performance was analyzed by using original least square regression, and the influence of three moderated variable (environment uncertainty, task uncertainty, and business strategy) to manager performance were analyzed by using Moderated Regression Analysis (MRA). The analysis result showed that accounting information variable influenced manager performance significantly. Meanwhile, the variables of environment uncertainty, task uncertainty, and business strategy did not moderate the influence of accounting information to manager performance.In other words, those three variables could not be said as moderated variables. The result showed indication of the importance of accounting information in doing management’s function Keywords: accounting information, the manager’s performance evaluation, environment uncertainty, task uncertainty, and business strategy.
Fenomena Manajemen Laba dalam IPO (Initial Public Offering); Studi dengan Menggunakan Model Aharony dan Friedlan
Authors: Waspodo Lego
Published: February 2020

The research was done on PT Multistrada Arah Sarana, during 2002 to 2007, using modified- Jones Model. The research used two means differentiation tests. Based on the result of two means differentiation test, it can be said that there was no income increasing discretionary accruals one year before initial public offering (on 2004). Issuers also did not do income-decreasing discretionary accruals on one year after initial public offering and two years after initial public offering. Hipotesis 1 and hipotesis 2 a and 2 b were refused, or can not be accepted. So, it can be concluded that PT Multisrada Arah Sarana did not do income smoothing before and after initial public offering on Indonesia Stock Exchange. Keywords: income smoothing, income increasing discretionary accruals, income decreasing discretionary accruals, initial public offering.
Panduan bagi Penulis
Authors: Jurnal Admin
Published: February 2020

A. Jenis Kontribusi 1. JRAK memublikasikan tulisan dalam bentuk artikel konseptual (conceptual paper) dan/atau artikel hasil penelitian (research paper) yang termasuk dalam bidang ilmu Akuntansi dan Keuangan. Objek kajian tulisan dapat meliputi tema-tema tentang kewirausahaan, sektor publik, keuangan syari’ah, knowledge management, dan intellectual capital.2. Naskah belum pernah dipublikasikan dan/atau tidak sedang didaftarkan untuk dipublikan pada publikasi lain.3. Semua naskah akan direview oleh dua orang mitra bestari dengan standar penilaian yang telah ditentukan.4. Ketika naskah dinyatakan diterima, maka penulis diminta untuk mengirim surat pernyataan keaslian/non-plagiarism. B. Ketentuan Umum 1. Naskah ditulis dalam bahasa Indonesia atau bahasa Inggris2. Naskah ditulis dengan program MS. Word dan disimpan dalam format “word for windows” dalam satu kolom dengan spasi ganda (double space).3. Seluruh halaman dalam naskah harus diberi nomor halaman di bagian bawah kanan, dimulai dari nomor 1. Ukuran kertas yang digunakan adalah A4 dengan margin 3.0 cm untuk semua sisi.4. Jenis font yang digunakan adalah “Times New Roman” 12pt.5. Panjang naskah tidak lebih dari 16-18 halaman, dan tidak diperkenankan mencantumkan lampiran.6. Semua tabel dan gambar diketik dalam halaman yang sama dalam naskah dan diberi nomor sesuai urutan kemunculannya serta diberi judul yang sesuai.7. Penggunaan istilah asing harus mengacu pada standar yang telah ditetapkan (gunakan GLOSARIUM). 8. Naskah dikirim lewat email (dalam bentuk attachment file) dan/atau lewat pos (dalam bentuk CD dan hard copy). C. Struktur Naskah Secara umum, naskah harus disusun dalam urutan sebagai berikut: Judul; Abstract; Pendahuluan; Metode; Hasil dan Pembahasan; Simpulan; ucapan terima kasih (pilihan); dan Daftar Pustaka. Sub judul harus ditulis dengan huruf besar dan tebal (bold capital) dan diletakkan di tengah-tengah halaman.
PengaruhIntellectual Capital Terhadap Kinerja Keuangan Perusahaan Publik (Non Keuangan) di Indonesia
Authors: Ifada Luluk Muhimatul , Hapsari Hairida
Published: February 2020

uBusinesses began to realize that the ability to compete not only in the ownership of industrial machines, but more on innovation, information systems, organizational management and human resource knowledge he had. An attempt will be able to compete when using competitive advantage gained through creative innovations produced by the intellectual capital of the company. Therefore, the Intellectual Capital (IC) has become a very valuable asset in the modern business world because it is necessary to create value added for the company. This study aims to determine the effect of IC on corporate financial performance. IC is an independent variable and the company’s financial performance as the dependent variable. Data used in this study is 215 public companies (non financial) in Indonesia from 2005 until 2008 which are listed on the Indonesia Stock Exchange (BEI). This research uses Pulic model (Value Added Intellectual Coefficient ™ - VAIC ™) as a measure of IC components that proxies with physical capital (vaca), human capital (VAHU), and structural capital (STVA). Partial Least Square (PLS) is used as a tool to test the effect of IC (VAIC ™) to the company’s financial performance, which the company’s financial performance proxies with the ROE, EPS and MBV. The results of this study indicate that: IC (VAIC ™) positive effect on company financial performance; IC (VAIC ™) positive effect on company financial performance in the future, the average growth of IC (ROGIC) no positive effect on corporate financial performance in the future front, and the contribution of IC (VAIC ™) against the company’s financial performance in the future will differ according to type of industry. Keywords: Intellectual Capital, (VAIC ™), the company’s financial performance, Partial Least Square (PLS).