bluuebunny/crossref_metadata_2025 huggingface dataset:
Through-container, extremely low concentration detection of multiple chemical markers of counterfeit alcohol using a handheld SORS device
Authors: Ellis David I. , Eccles Rebecca , Xu Yun , Griffen Julia , Muhamadali Howbeer , Matousek Pavel , Goodall Ian , Goodacre Royston
Published: September 2017

Major food adulteration incidents occur with alarming frequency and are episodic, with the latest incident, involving the adulteration of meat from 21 producers in Brazil supplied to 60 other countries, reinforcing this view. Food fraud and counterfeiting involves all types of foods, feed, beverages, and packaging, with the potential for serious health, as well as significant economic and social impacts. In the spirit drinks sector, counterfeiters often ‘recycle’ used genuine packaging, or employ good quality simulants. To prove that suspect products are non-authentic ideally requires accurate, sensitive, analysis of the complex chemical composition while still in its packaging. This has yet to be achieved. Here, we have developed handheld spatially offset Raman spectroscopy (SORS) for the first time in a food or beverage product, and demonstrate the potential for rapid in situ through-container analysis; achieving unequivocal detection of multiple chemical markers known for their use in the adulteration and counterfeiting of Scotch whisky, and other spirit drinks. We demonstrate that it is possible to detect a total of 10 denaturants/additives in extremely low concentrations without any contact with the sample; discriminate between and within multiple well-known Scotch whisky brands, and detect methanol concentrations well below the maximum human tolerable level.
A tight binding and $$\overrightarrow{{\boldsymbol{k}}}\cdot \overrightarrow{{\boldsymbol{p}}}$$ study of monolayer stanene
Authors: Jiang Liming , Marconcini Paolo , Hossian Md Sharafat , Qiu Wanzhi , Evans Robin , Macucci Massimo , Skafidas Efstratios
Published: September 2017

Stanene is a single layer of tin atoms which has been discovered as an emerging material for quantum spin Hall related applications. In this paper, we present an accurate tight-binding model for single layer stanene near the Fermi level. We parameterized the onsite and hopping energies for the nearest, second nearest, and third nearest neighbor tight-binding method, both without and with spin orbital coupling. We derived the analytical solution for the $$\overrightarrow{{\boldsymbol{\Gamma }}}$$

Γ
→

and $$\overrightarrow{{\boldsymbol{K}}}$$

K
→

points and numerically investigated the buckling effect on the material electronic properties. In these points of the reciprocal space, we also discuss a corresponding $$\overrightarrow{{\boldsymbol{k}}}\cdot \overrightarrow{{\boldsymbol{p}}}$$

k
→

⋅

p
→

description, obtaining the value of the $$\overrightarrow{{\boldsymbol{k}}}\cdot \overrightarrow{{\boldsymbol{p}}}$$

k
→

⋅

p
→

parameters both analytically from the tight-binding ones, and numerically, fitting the ab-initio dispersion relations. Our models provide a foundation for large scale atomistic device transport calculations.
Bitter or not? BitterPredict, a tool for predicting taste from chemical structure
Authors: Dagan-Wiener Ayana , Nissim Ido , Ben Abu Natalie , Borgonovo Gigliola , Bassoli Angela , Niv Masha Y.
Published: September 2017

Bitter taste is an innately aversive taste modality that is considered to protect animals from consuming toxic compounds. Yet, bitterness is not always noxious and some bitter compounds have beneficial effects on health. Hundreds of bitter compounds were reported (and are accessible via the BitterDB http://bitterdb.agri.huji.ac.il/dbbitter.php), but numerous additional bitter molecules are still unknown. The dramatic chemical diversity of bitterants makes bitterness prediction a difficult task. Here we present a machine learning classifier, BitterPredict, which predicts whether a compound is bitter or not, based on its chemical structure. BitterDB was used as the positive set, and non-bitter molecules were gathered from literature to create the negative set. Adaptive Boosting (AdaBoost), based on decision trees machine-learning algorithm was applied to molecules that were represented using physicochemical and ADME/Tox descriptors. BitterPredict correctly classifies over 80% of the compounds in the hold-out test set, and 70–90% of the compounds in three independent external sets and in sensory test validation, providing a quick and reliable tool for classifying large sets of compounds into bitter and non-bitter groups. BitterPredict suggests that about 40% of random molecules, and a large portion (66%) of clinical and experimental drugs, and of natural products (77%) are bitter.
Transcriptome analyses suggest a novel hypothesis for whitefly adaptation to tobacco
Authors: Xia Wen-Qiang , Wang Xin-Ru , Liang Yan , Liu Shu-Sheng , Wang Xiao-Wei
Published: September 2017

The adaptation of herbivorous insects to various host plants facilitates the spread and outbreak of many important invasive pests, however, the molecular mechanisms that underneath this process are poorly understood. In the past three decades, two species of the whitefly Bemisia tabaci complex, Middle East-Asia Minor 1 and Mediterranean, have invaded many countries. Their rapid and widespread invasions are partially due to their ability to infest a wide range of host plants. In this study, we determined the transcriptome and phenotypic changes of one Mediterranean whitefly population during its adaptation to tobacco, an unsuitable host plant. After several generations on tobacco, whiteflies showed increased survival and fecundity. High-throughput RNA sequencing showed that genes involved in muscle contraction and carbohydrate metabolism were significantly up-regulated after adaptation. Whiteflies reared on tobacco were further found to have increased body volume and muscle content and be trapped by tobacco trichomes in a lower frequency. On the other hand, gene expression in endosymbionts of whitefly did not change significantly after adaptation, which is consistent with the lack of cis-regulatory element on endosymbiont genomes. Over all, our data suggested that higher body volume and strengthened muscle might help whiteflies overcome physical barriers and survive on tobacco.
Negative membrane capacitance of outer hair cells: electromechanical coupling near resonance
Authors: Iwasa Kuni H.
Published: September 2017

Outer hair cells in the cochlea have a unique motility in their cell body based on mechanoelectric coupling, with which voltage changes generated by stimuli at their hair bundles drive the cell body and, in turn, it has been assumed, amplifies the signal. In vitro experiments show that the movement of the charges of the motile element significantly increases the membrane capacitance, contributing to the attenuation of the driving voltage. That is indeed the case in the absence of mechanical load. Here it is predicted, however, that the movement of motile charges creates negative capacitance near the condition of mechanical resonance, such as those in the cochlea, enhancing energy output.
Decadal radon cycles in a hot spring
Authors: Yan Rui , Woith Heiko , Wang Rongjiang , Wang Guangcai
Published: September 2017

Absatrct

A high-fidelity record covering nearly 40 years of water-dissolved radon from the hot spring site of BangLazhang (BLZ), Southwestern China is presented to study multi-year periodicities of radon. Ancillary observational data, i.e., water temperature, spring discharge rate, barometric pressure, combined with regional rainfall, galactic cosmic rays (GCR flux is modulated by solar wind and thus a proxy for solar activity) and regional seismicity from the same period are considered to identify potentially influencing factors controlling the changes in radon. Variations in radon concentration and ancillary observational data are studied using continuous Wavelet Power Spectrum (WPS), Wavelet Coherence (WTC), and Partial Wavelet Coherence (PWC). The results show that the long-period radon concentration is characterized by a quasi-decadal (8–11 years) cycle, matching well with the concurrent periodicity in water temperature, spring discharge rates and GCR. PWCs of radon, discharge rate and water temperature suggest that water temperature variations explain most of the coherent variability of radon and the discharge rate. We tentatively conclude that radon variations are mainly explained by variations in water temperature and spring discharge, which are modified and modulated by earthquakes and quasi-decadal variations of an unidentified process. The influence of solar activity on the decadal periodicity is discussed.
Regulation of axonal regeneration by the level of function of the endogenous Nogo receptor antagonist LOTUS
Authors: Hirokawa Tomoko , Zou Yixiao , Kurihara Yuji , Jiang Zhaoxin , Sakakibara Yusuke , Ito Hiromu , Funakoshi Kengo , Kawahara Nobutaka , Goshima Yoshio , Strittmatter Stephen M. , Takei Kohtaro
Published: September 2017

Axonal regeneration in the adult mammalian central nervous system is limited in part by the non-permissive environment, including axonal growth inhibitors such as the Nogo-A protein. How the functions of these inhibitors can be blocked remains unclear. Here, we examined the role of LOTUS, an endogenous Nogo receptor antagonist, in promoting functional recovery and neural repair after spinal cord injury (SCI), as well as axonal regeneration after optic nerve crush. Wild-type untreated mice show incomplete but substantial intrinsic motor recovery after SCI. The genetic deletion of LOTUS delays and decreases the extent of motor recovery, suggesting that LOTUS is required for spontaneous neural repair. The neuronal overexpression of LOTUS in transgenic mice promotes motor recovery after SCI, and recombinant viral overexpression of LOTUS enhances retinal ganglion cell axonal regeneration after optic nerve crush. Thus, the level of LOTUS function titrates axonal regeneration.
Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study
Authors: Sato Junko , Kanazawa Akio , Azuma Kosuke , Ikeda Fuki , Goto Hiromasa , Komiya Koji , Kanno Rei , Tamura Yoshifumi , Asahara Takashi , Takahashi Takuya , Nomoto Koji , Yamashiro Yuichiro , Watada Hirotaka
Published: September 2017

Gut bacterial translocation to the blood may play an important role in the development of insulin resistance in type 2 diabetes. Here, we performed an interventional randomised control study to investigate whether probiotics could reduce bacterial translocation and cause changes in the gut microbiota. Seventy Japanese patients with type 2 diabetes were randomised to two groups: the probiotic group drank Lactobacillus casei strain Shirota-fermented milk, while the control group ingested no probiotics. The trial was conducted for 16 weeks. At baseline, 8 and 16 weeks, the gut microbiota composition in feces and blood, fecal organic acids, and other biochemical parameters were measured. At the end of the study, the fecal counts of the Clostridium coccoides group and Clostridium leptum subgroup in the probiotic group were significantly higher than in the control group. As expected, the fecal counts of total Lactobacillus were significantly higher in the probiotic group. Intriguingly, the total count of blood bacteria was significantly lower in the probiotic group. However, fecal organic acids were comparable between the two groups. Our results showed that probiotic administration reduced bacterial translocation and altered the gut microbiota in Japanese patients with type 2 diabetes mellitus.
Old Yellow Enzyme homologues in Mucor circinelloides: expression profile and biotransformation
Authors: Romagnolo Alice , Spina Federica , Poli Anna , Risso Sara , Serito Bianca , Crotti Michele , Monti Daniela , Brenna Elisabetta , Lanfranco Luisa , Varese Giovanna Cristina
Published: September 2017

The reduction of C=C double bond, a key reaction in organic synthesis, is mostly achieved by traditional chemical methods. Therefore, the search for enzymes capable of performing this reaction is rapidly increasing. Old Yellow Enzymes (OYEs) are flavin-dependent oxidoreductases, initially isolated from Saccharomyces pastorianus. In this study, the presence and activation of putative OYE enzymes was investigated in the filamentous fungus Mucor circinelloides, which was previously found to mediate C=C reduction. Following an in silico approach, using S. pastorianus OYE1 amminoacidic sequence as template, ten putative genes were identified in the genome of M. circinelloides. A phylogenetic analysis revealed a high homology of McOYE1-9 with OYE1-like proteins while McOYE10 showed similarity with thermophilic-like OYEs. The activation of mcoyes was evaluated during the transformation of three different model substrates. Cyclohexenone, α-methylcinnamaldehyde and methyl cinnamate were completely reduced in few hours and the induction of gene expression, assessed by qRT-PCR, was generally fast, suggesting a substrate-dependent activation. Eight genes were activated in the tested conditions suggesting that they may encode for active OYEs. Their expression over time correlated with C=C double bond reduction.
High-accuracy and high-sensitivity spectroscopic measurement of dinitrogen pentoxide (N2O5) in an atmospheric simulation chamber using a quantum cascade laser
Authors: Yi Hongming , Wu Tao , Lauraguais Amélie , Semenov Vladimir , Coeur Cecile , Cassez Andy , Fertein Eric , Gao Xiaoming , Chen Weidong
Published: September 2017

A spectroscopic instrument based on a mid-infrared external cavity quantum cascade laser was developed for high-accuracy measurements of N2O5 at the ppbv-level.
Correction: Normalization strategy for the LC-MS bioanalysis of protein kinetics assays via internal proteolytic analyte utilized as control standard: application in studies of HIV-1 protease cleavage of HIV-1 Gag polyprotein in HIV maturation inhibition research
Authors: Cantone Joseph L. , Lin Zeyu , Dicker Ira B. , Drexler Dieter M.
Published: September 2017

Correction for ‘Normalization strategy for the LC-MS bioanalysis of protein kinetics assays via internal proteolytic analyte utilized as control standard: application in studies of HIV-1 protease cleavage of HIV-1 Gag polyprotein in HIV maturation inhibition research’ by Joseph L. Cantone et al., Anal. Methods, 2017, DOI: 10.1039/c7ay01666b.
Phase transformation from α-Fe2O3to Fe3O4and LiFeO2by the self-reduction of Fe(iii) in Prussian red in the presence of alkali hydroxides: investigation of the phase dependent morphological and magnetic properties
Authors: Thiruppathi K. Palani , Nataraj Devaraj
Published: September 2017

A simple surfactant and calcination free phase transformation from hematite to magnetite and lithium ferrite with a number of different morphologies was obtained.
On kinetic modelling for solar redox thermochemical H2O and CO2 splitting over NiFe2O4 for H2, CO and syngas production
Authors: Dimitrakis Dimitrios A. , Syrigou Maria , Lorentzou Souzana , Kostoglou Margaritis , Konstandopoulos Athanasios G.
Published: September 2017

Kinetic parameters for solar thermochemical H2O and CO2 splitting over NiFe2O4 structures including transition times and multi-cycle operation simulation.
Self-assembled morphologies of an amphiphilic Y-shaped weak polyelectrolyte in a thin film
Authors: Mu Dan , Li Jian-Quan , Feng Sheng-Yu
Published: September 2017

The introduction of charges leads to a smaller aggregate size and lower density; moreover, crossed-cylindrical structures are produced in thicker thin films.
Correction: Observation of crystalline changes of titanium dioxide during lithium insertion by visible spectrum analysis
Authors: Nam Inho , Park Jongseok , Park Soomin , Bae Seongjun , Yoo Young Geun , Han Jeong Woo , Yi Jongheop
Published: September 2017

Correction for ‘Observation of crystalline changes of titanium dioxide during lithium insertion by visible spectrum analysis’ by Inho Nam et al., Phys. Chem. Chem. Phys., 2017, 19, 13140–13146.
Investigation of the highly tunable selectivity to linear α-olefins in Fischer–Tropsch synthesis over silica-supported Co and CoMn catalysts by carburization–reduction pretreatment
Authors: Zheng Jiao , Cai Jian , Jiang Feng , Xu Yuebing , Liu Xiaohao
Published: September 2017

An efficient strategy to tune the selectivity to α-olefins in FTS over Co-based catalysts has been developed.
Tantallacyclopentadiene as a unique metal-containing diene ligand coordinated to nickel for preparing tantalum–nickel heterobimetallic complexes
Authors: Laskar Payel , Yamamoto Keishi , Srinivas Anga , Mifleur Alexis , Nagae Haruki , Tsurugi Hayato , Mashima Kazushi
Published: September 2017

The mononuclear tantallacyclopentadiene, TaCl3(C4H2tBu2), coordinates to Ni to form heterobimetallic complexes of Cl3Ta(μ-C4H2tBu2)Ni(L) (L = COD, phosphines, IPr).
Structure dependence of intramolecular electron transfer reactions of simple dyads of a zinc(ii) porphyrin complex bearing a peripheral bipyridine moiety
Authors: Sakakibara Kei , Nagino Shou , Akanuma Hajime , Tsukada Yuki , Nakano Hirofumi , Yagyu Takeyoshi , Takagi Hideo D. , Inamo Masahiko
Published: September 2017

Photoinduced intramolecular electron transfer and charge recombination reactions were investigated using various Zn(ii)-porphyrin dyads having a 2,2′-bipyridine moiety.
Development and experimental validation of the composition and treatability of a new synthetic bathroom greywater (SynGrey)
Authors: Thompson Kyle A. , Summers R. Scott , Cook Sherri M.
Published: September 2017

A new synthetic greywater—SynGrey—was developed that closely matches real bathroom greywater in composition and treatability.
Antioxidant and hypolipidemic effects of soymilk fermentedvia Lactococcus acidophilusMF204
Authors: Chen Jie , Wu Yan , Yang Chunmei , Xu Xuejiao , Meng Yuecheng
Published: September 2017

Previous studies have shown that fermentations can enhance the bioactivity and absorption rate of soybean products.
Cu(ii) immobilized on Fe3O4@APTMS-DFX nanoparticles: an efficient catalyst for the synthesis of 5-substituted 1H-tetrazoles with cytotoxic activity
Authors: Taghavi Faezeh , Gholizadeh Mostafa , Saljooghi Amir Sh. , Ramezani Mohammad
Published: September 2017

The potential of Cu(ii) immobilized on Fe3O4@APTMS-DFX nanoparticles as a novel magnetically recyclable heterogeneous catalyst for the synthesis of 5-substituted 1H-tetrazoles and anti-proliferative agent.
Cooperative vibrational properties of hydrogen bonds in Watson–Crick DNA base pairs
Authors: Shi Yulei , Jiang Wanrun , Zhang Zhiyuan , Wang Zhigang
Published: September 2017

For the AT pair, Symst and Strech peaks further shift toward the red, giving the H-bonds an amplified effect (orange arrows).
Visualizing and quantifying the nanoscale hydrophobicity and chemical distribution of surface modified polyethersulfone (PES) membranes
Authors: Fu Wanyi , Carbrello Christina , Wu Xiaosong , Zhang Wen
Published: September 2017

Atomic force microscopy (AFM) and AFM-IR were used to resolve the nanoscale hydrophobicity and chemical distribution of chemically modified polyethersulfone membranes.
In vitro biocatalytic pathway design: orthogonal network for the quantitative and stereospecific amination of alcohols
Authors: Knaus Tanja , Cariati Luca , Masman Marcelo F. , Mutti Francesco G.
Published: September 2017

An artificial, orthogonal, biocatalytic network converts alcohols quantitatively into enantiopure amines, consuming ammonia and dioxygen and generating carbonate as by-product.
Transition-metal-catalyzed divergent functionalization of [60]fullerene with propargylic esters
Authors: Yamada Michio , Ochi Rika , Yamamoto Yuhei , Okada Sae , Maeda Yutaka
Published: September 2017

Transition-metal-catalyzed divergent reactions between C60 and propargylic esters allow easy access to formal [2 + 2] and [4 + 2] cycloadducts.
Mono- and double carbonylation of aryl iodides with amine nucleophiles in the presence of recyclable palladium catalysts immobilised on a supported dicationic ionic liquid phase
Authors: Papp M. , Szabó P. , Srankó D. , Sáfrán G. , Kollár L. , Skoda-Földes R.
Published: September 2017

Silica modified with organic dicationic moieties proved to be an excellent support for palladium catalysts used in the aminocarbonylation of aryl iodides.
Molecular dynamics simulation of Keggin HPA doped Nafion® 117 as a polymer electrolyte membrane
Authors: Akbari S. , Mosavian M. T. Hamed , Moosavi F. , Ahmadpour A.
Published: September 2017

Nafion®/heteropoly acid (HPA) composite membranes and the impact of the anionic charge of HPA on water and hydronium dynamics were investigated using molecular dynamics simulation.
Electrospray-mediated preparation of compositionally homogeneous core–shell hydrogel microspheres for sustained drug release
Authors: Lai Wing-Fu , Susha Andrei S. , Rogach Andrey L. , Wang Guoan , Huang Minjian , Hu Weijie , Wong Wing-Tak
Published: September 2017

Compositionally homogeneous core–shell hydrogel microspheres were prepared for sustained drug release.
Half-metals and half-semiconductors in a transition metal doped SnSe2 monolayer: a first-principles study
Authors: Wu Xuming , Han Jiangchao , Feng Yulin , Li Guanpeng , Wang Cong , Ding Guangqian , Gao Guoying
Published: September 2017

Recently, a new two-dimensional (2D) semiconductor SnSe2 monolayer has been grown by molecular beam epitaxy, and weak ferromagnetic behavior above room temperature in Mn-doped SnSe2 thin films was also observed experimentally.
Bioinspired fabrication of macroporous calcium carbonate crystals mediated by thermoresponsive copolymers
Authors: Shi Siyu , Cai Long , Liu Xue , Li Haonan , Gao Yuan , Wu Qiuhua , Yi Jie , Song Ximing , Zhang Guolin
Published: September 2017

Scheme showing the growth mechanism of the CaCO3 crystals at 50 °C.
Facet-dependent magnesiation behavior of α-Sn as an anode for magnesium ion batteries
Authors: Jin Wei , Wang Zhiguo
Published: September 2017

Mg diffusion from the surface to the subsurface is the rate-limiting step for Sn used as an anode for MIBs.
Antagonistic effects of selenium against necroptosis injury via adiponectin-necrotic pathway induced by cadmium in heart of chicken
Authors: Cai Jingzeng , Zhang Yuan , Yang Jie , Liu Qi , Zhao Rihong , Hamid Sattar , Wang Hong , Xu Shiwen , Zhang Ziwei
Published: September 2017

Cadmium (Cd) is one of the most toxic heavy metals having a destructive impact on various organ systems.
Arsenene/Ca(OH)2 van der Waals heterostructure: strain tunable electronic and photocatalytic properties
Authors: Li Xiao-Hua , Wang Bao-Ji , Cai Xiao-Lin , Yu Wei-Yang , Zhang Li-Wei , Wang Guo-Dong , Ke San-Huang
Published: September 2017

Based on ab initio calculations, we identify that the arsenene/Ca(OH)2 van der Waals heterostructure is an indirect-band-gap semiconductor and find that its electronic and photocatalytic properties can be continuously tuned by external strain.
Bicyclo[6.1.0]nonyne and tetrazine amino acids for Diels–Alder reactions
Authors: Li Xu , Liu Zhengkun , Dong Shouliang
Published: September 2017

Here we report a general method for the de novo synthesis of a bicyclo[6.1.0]nonyne group containing an amino acid, and used Marfey's reagent for chiral analysis.
Magnetic solid phase extraction based on graphene oxide/nanoscale zero-valent iron for the determination of tetracyclines in water and milk by using HPLC-MS/MS
Authors: Wei Dan , Wu Shuchao , Zhu Yan
Published: September 2017

A magnetic solid-phase extraction (MSPE) based on graphene oxide/nanoscale zero-valent iron (GO/nZVI) coupled with HPLC-MS/MS was proposed for the determination of trace tetracycline antibiotics (TCs) in water and milk.
An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization
Authors: Yue Weiwei , Tang Caiyan , Wang Chunxing , Bai Chengjie , Liu Shuyi , Xie Xiaohui , Hua Hongling , Zhang Zhen , Li Dengwang
Published: September 2017

In this paper, an electricity-fluorescence double-checking biosensor based on graphene materials has been presented for detection of DNA hybridization kinetics.
Folate chitosan conjugated doxorubicin and pyropheophorbide acid nanoparticles (FCDP–NPs) for enhance photodynamic therapy
Authors: Li Wenting , Tan Guanghui , Zhang Hongyue , Wang Zhiqiang , Jin Yingxue
Published: September 2017

Newly prepared folate chitosan conjugated doxorubicin and pyropheophorbide acid nanoparticles (FCDP–NPs) showed remarkable PDT activity against HepG2 cells.
Chitosan–gold nanoparticles as peroxidase mimic and their application in glucose detection in serum
Authors: Jiang Cuifeng , Zhu Jing , Li Zhao , Luo Juhua , Wang Jinshan , Sun Yu
Published: September 2017

Chitosan–AuNPs possess peroxidase-like activity and can be used for the detection of glucose in serum.
Condensation effect-induced improved sensitivity for SERS trace detection on a superhydrophobic plasmonic nanofibrous mat
Authors: Liang Xiaohong , Zhang Han , Xu Cheng , Cao Ding , Gao Qiang , Cheng Si
Published: September 2017

Superhydrophobic PAN/noble metal nanofibrous mats prove to be highly SERS-sensitive substrates for the trace detection of analyte molecules due to the condensation effect.
Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species
Authors: Li Yuyan , Yang Jian , Liu Hongwu , Yang Jing , Du Lei , Feng Haiwei , Tian Yanli , Cao Jianqin , Ran Chongzhao
Published: September 2017

We demonstrate that tuning the stereo-hindrance of the phenoxy-alkyl chains at the 4-position of a curcumin scaffold could lead to certain selectivity for soluble Aβs over insoluble Aβs.
Cu(ii) and Zn(ii) based phthalocyanines as hole selective layers for perovskite solar cells
Authors: Caliò Laura , Follana-Berná Jorge , Kazim Samrana , Madsen Morten , Rubahn Horst-Günter , Sastre-Santos Ángela , Ahmad Shahzada
Published: September 2017

Cu and Zn based phthalocyanines with 4-tert-octylphenoxy-substituted functional groups were synthesized and showed high solubility in a range of organic solvents, they were integrated in perovskite solar cells.
Friction controls even submerged granular flows
Authors: Koivisto Juha , Korhonen Marko , Alava Mikko , Ortiz Carlos P. , Durian Douglas J. , Puisto Antti
Published: September 2017

A recently discovered counterintuitive surge in granular hopper flows is successfully modeled using discrete elements coupled with computational fluid mechanics.
Multiple particle tracking study of thermally-gelling nanoemulsions
Authors: Cheng Li-Chiun , Hsiao Lilian C. , Doyle Patrick S.
Published: September 2017

We demonstrate that, by tailoring the MPT probe surface chemistry, we can control the residence of probes in each domain in thermally-gelling nanoemulsions, thus allowing us to independently probe each phase at rising temperatures.
Feasibility of using microencapsulated phase change materials as filler for improving low temperature performance of rubber sealing materials
Authors: Tiwari Avinash , Shubin Sergey N. , Alcock Ben , Freidin Alexander B. , Thorkildsen Brede , Echtermeyer Andreas T.
Published: September 2017

The feasibility of microencapsulated phase change material (MEPCM) as filler in a rubber sealing material to improve sealing under transient cooling (in a so-called blowdown scenario) is investigated here.
N-doped carbon-dots for luminescent solar concentrators
Authors: Li Yunxia , Miao Peng , Zhou Wei , Gong Xiao , Zhao Xiujian
Published: September 2017

N-doped carbon-dots (N-CDs) are for the first time reported to be used as phosphors for LSC fabrication.
Recent advances in plasmonic metal and rare-earth-element upconversion nanoparticle doped perovskite solar cells
Authors: Kakavelakis G. , Petridis K. , Kymakis E.
Published: September 2017

Literature review of metal and rare-earth-element nanoparticles doped in the device building blocks of mesoscopic and planar perovskite solar cells.
A sulfonimide-based alternating copolymer as a single-ion polymer electrolyte for high-performance lithium-ion batteries
Authors: Cao Chen , Li Yu , Feng Yiyu , Long Peng , An Haoran , Qin Chengqun , Han Junkai , Li Shuangwen , Feng Wei
Published: September 2017

A novel sulfonimide-based single-ion conductor with an alternating structure as a polymer electrolyte for high-performance lithium-ion batteries.
Fabricating efficient CdSe–CdS photocatalyst systems by spatially resetting water splitting sites
Authors: Wang Zhijian , Wang Junmei , Li Li , Zheng Jianfeng , Jia Suping , Chen Jiazang , Liu Bin , Zhu Zhenping
Published: September 2017

Modulating reaction sites and charge transfer can speed up the photocatalytic hydrogen generation rate from 1.0 to 1270 mmol g−1 h−1.
Fabrication of membrane absorbers based on amphiphilic carbonaceous derivatives for selective endotoxin clearance
Authors: Wu Qiang , Xu Yueyue , Yang Kai , Cui Hailei , Chen Yanjun , Wang Menghua , Zhu Qingke , Kang Wenyi , Gao Chunsheng
Published: September 2017

A new carrier-dispersed method based on amphiphilic carbonaceous particles (ACPs) was developed for the construction of functionalized blend membrane absorbers.
Rapid thermal thinning of black phosphorus
Authors: Fan Shuangqing , Hei Haicheng , An Chunhua , Pang Wei , Zhang Daihua , Hu Xiaodong , Wu Sen , Liu Jing
Published: September 2017

Two-step rapid thermal thinning obtains monolayer black phosphorus with a high surface quality.
Enhanced dielectric properties due to space charge-induced interfacial polarization in multilayer polymer films
Authors: Chen Xinyue , Tseng Jung-Kai , Treufeld Imre , Mackey Matthew , Schuele Donald E. , Li Ruipeng , Fukuto Masafumi , Baer Eric , Zhu Lei
Published: September 2017

Interfacial polarization due to space charges enhances electrical insulation and thus breakdown strength for multilayer polymer films.
Temperature regulation growth of Au nanocrystals: from concave trisoctahedron to dendritic structures and their ultrasensitive SERS-based detection of lindane
Authors: Zhou Xia , Zhao Qian , Liu Guangqiang , Zhang Hongwen , Li Yue , Cai Weiping
Published: September 2017

A facile temperature regulation strategy is developed to fabricate Au concave nanocrystals with strong SERS activity towards lindane molecules.
Error Type and Lexical Frequency Effects: Error Detection in Swedish Children With Language Impairment
Authors: Hallin Anna Eva , Reuterskiöld Christina
Published: September 2017

Purpose

The first aim of this study was to investigate if Swedish-speaking school-age children with language impairment (LI) show specific morphosyntactic vulnerabilities in error detection. The second aim was to investigate the effects of lexical frequency on error detection, an overlooked aspect of previous error detection studies.

Method

Error sensitivity for grammatical structures vulnerable in Swedish-speaking preschool children with LI (omission of the indefinite article in a noun phrase with a neuter/common noun, and use of the infinitive instead of past-tense regular and irregular verbs) was compared to a control error (singular noun instead of plural). Target structures involved a high-frequency (HF) or a low-frequency (LF) noun/verb. Grammatical and ungrammatical sentences were presented in headphones, and responses were collected through button presses.

Results

Children with LI had similar sensitivity to the plural control error as peers with typical language development, but lower sensitivity to past-tense errors and noun phrase errors. All children showed lexical frequency effects for errors involving verbs (HF > LF), and noun gender effects for noun phrase errors (common > neuter).

Conclusions

School-age children with LI may have subtle difficulties with morphosyntactic processing that mirror expressive difficulties in preschool children with LI. Lexical frequency may affect morphosyntactic processing, which has clinical implications for assessment of grammatical knowledge.
Investigating the Role of Salivary Cortisol on Vocal Symptoms
Authors: Holmqvist-Jämsén Sofia , Johansson Ada , Santtila Pekka , Westberg Lars , von der Pahlen Bettina , Simberg Susanna
Published: September 2017

Purpose

We investigated whether participants who reported more often occurring vocal symptoms showed higher salivary cortisol levels and if such possible associations were different for men and women.

Method

The participants (N= 170; menn= 49, womenn= 121) consisted of a population-based sample of Finnish twins born between 1961 and 1989. The participants submitted saliva samples for hormone analysis and completed a web questionnaire including questions regarding the occurrence of 6 vocal symptoms during the past 12 months. The data were analyzed using the generalized estimated equations method.

Results

A composite variable of the vocal symptoms showed a significant positive association with salivary cortisol levels (p< .001). Three of the 6 vocal symptoms were significantly associated with the level of cortisol when analyzed separately (pvalues less than .05). The results showed no gender difference regarding the effect of salivary cortisol on vocal symptoms.

Conclusions

There was a positive association between the occurrence of vocal symptoms and salivary cortisol levels. Participants with higher cortisol levels reported more often occurring vocal symptoms. This could have a connection to the influence of stress on vocal symptoms because stress is a known risk factor of vocal symptoms and salivary cortisol can be seen as a biomarker for stress.
The Development of Speech-Language Pathology in Zambia: A Reflection on the Current Landscape and Two Contrasting Training Models
Authors: Bright Suzanna , Selemani Chisomo
Published: September 2017

Functional approaches to disability measurement in Zambia reveals an overall disability prevalence rate of 13.4%, 4% of whom are recorded as having “speech impairment” (Zambia Federation of the Disabled [ZAFOD], 2006). Further, multidimensional poverty assessments indicate that 48.6% of Zambia's approximately 16 million citizens are impoverished. Currently, there are three internationally qualified speech-language pathologists (SLPs) providing services within Zambia's capital city, Lusaka. Given these statistics, it follows that a significant number of Zambian's, experiencing communication disability, are unable to access specialist assessment and support. Over the past decade, Zambia has seen two very different approaches to address this service gap—firstly, a larger scale top-down approach through the implementation of a formal master's degree program and more recently a smaller scale, bottom-up approach, building the capacity of existing professionals working in the field of communication disability. This article provides an overview of both programs and the context, unique to Zambia, in which they have developed. Authors describe the implementation challenges encountered and program successes leading to a discussion of the weakness and merits to both programs, in an attempt to draw lessons from which future efforts to support communication disability and SLP service development in Majority World contexts may benefit.
Chaos theory‐based NHZ‐FH sequence set for quasi‐synchronous FHMA system
Authors: Zeng Qi , Liu Xing
Published: September 2017

Uniformity, good Hamming‐correlation and long period are critical requirements for frequency‐hopping (FH) sequence set. A new class of no‐hit zone FH (NHZ‐FH) sequence set is designed based on chaotic nonlinear map to meet above three demands. Some properties of the proposed sequence set and its performance for frequency‐hopping‐multiple‐access (FHMA) system are investigated. The results show that the proposed NHZ‐FH sequence set can offer more robustness to eavesdropper and lower BER for quasi‐synchronous FHMA system in comparison with other traditional FH sequence sets.
A fast numerical method for optimal coordination of overcurrent relays in the presence of transient fault current
Authors: Mohammadi Chabanloo Reza , Mohammadzadeh Nima
Published: September 2017

In the past, many studies have been conducted on the optimal coordination of overcurrent (OC) relays. In these studies, the short‐circuit current flowing through the relays is considered as fixed. In a real power network, however, for various reasons including the transient behaviour of synchronous generators, the short‐circuit current that flows through the relays varies with time. Therefore, the relay settings, which are obtained with the assumption of a constant, short‐circuit current, may cause miss‐coordination under real conditions. In this study, a numerical method based on the dynamic model of the relay is presented using linear programming (LP) to take account of the effect of transient currents on the coordination of OC relays. The method can be used as a fast numerical algorithm in the computing software to obtain accurate settings for OC relays in the presence of various transient fault currents in the network. Furthermore, the combination of LP with a genetic algorithm is used to incorporate the current setting of the relays in the transient coordination algorithm to achieve a better operating time for the relays. The results show the effectiveness of the proposed algorithms as compared with the previously presented method.
Magnetising‐current‐assisted wide ZVS range push–pull DC/DC converter with reduced circulating energy
Authors: Xu Jialin , Wu Qunfang , Wang Yu
Published: September 2017

An improved high efficiency wide zero‐voltage‐switching (ZVS) range push–pull converter for low‐voltage to high‐voltage power conversion is proposed in this study. For this improved converter, all of primary switches are turned on with ZVS operation from full load to light load by using the energy stored in the leakage inductance aided by the magnetising inductance. The resonance between the leakage inductor and the voltage‐doubler‐rectifier capacitors reduces not only the voltage and current stresses of rectifier diodes but also the turns ratio of high‐frequency transformer and conduction loss. In addition, the circulating energy is decreased dramatically compared with the similar converter resulting in lower conduction loss. This topology features simpler structure and higher efficiency. Detailed operational principle, design, comparative study and experimental results are fully discussed in the text. Finally, a 200 W experimental prototype has been built to verify the effectiveness of the proposed concept.
New Facile Synthesis of Adamantyl Isothiocyanates
Authors: Burmistrov Vladimir , Pitushkin Dmitry , Butov Gennady
Published: September 2017

A series of adamantyl isothiocyanates containing different substituents in the nodal positions of adamantane or spacers between the adamantane and isothiocyanate group have been synthesised by using the reaction of the corresponding adamantyl amines with phenyl isothiocyanate.
Comparison of Platelet-Rich Plasma, Stromal Vascular Fraction (SVF), or SVF with an Injectable PLGA Nanofiber Scaffold for the Treatment of Osteochondral Injury in Dogs
Authors: Stoker Aaron , Bozynski Chantelle , Kuroki Keiichi , Clarke Kevin , Johnson Jed , Cook James , Franklin Samuel
Published: September 2017

Stromal vascular fraction (SVF) contains a small number of mesenchymal stem cells and has been used as a treatment for osteoarthritis and cartilage injury. Due to limited evidence of successful cartilage regeneration with injected stem cell therapies, there is interest in combining cellular therapies with injectable scaffolding materials to increase intra-articular residence times of stem cells and improve tissue regeneration. However, the safety of intra-articular injection of SVF combined with injectable scaffolds is unestablished. Also, it is unclear if SVF therapy is superior to more easily prepared biologics, such as platelet-rich plasma (PRP). The purpose of this study was to assess the safety of SVF when combined with an injectable poly(L-lactide-co-glycolide) nanofiber scaffold and to provide a comparison of SVF therapy to PRP. A total of 12 Beagles had osteochondral defects created in both medial femoral condyles and 4 dogs each were allocated to treatment groups of SVF (n = 4), SVF plus PLGA scaffolding (n = 4), or leukoreduced PRP (n = 4). One knee in each dog received treatment, and the contralateral knee was sham treated with saline. Dogs were assessed over a 6-month period, and outcome measures included functional, radiographic, biochemical, and histological assessments. PRP treatment resulted in improvements in lameness scores and objective kinetic assessments of function. There were no statistically significant improvements in function, cartilage biochemical composition, or histology for SVF-treated knees. The combination of SVF and the injectable PLGA scaffold had worse outcomes than other groups including sham treatment based upon functional, biochemical, and histological assessments, raising concerns over the safety of this scaffold for intra-articular injection.
Triggerpunkte bei Nacken- und Thoraxschmerz – Erfolgsrezept aus Hands-on und -off
Authors: Heitkamp Hauke
Published: September 2017

Anhand eines echten Fallbeispiels zeigt Hauke Heitkamp, wie sich Triggerpunkte durch ein strukturiertes Clinical Reasoning identifizieren und erfolgreich behandeln lassen. Zudem verdeutlicht er, warum Hands-on-Techniken nach wie vor ihre Berechtigung haben – vor allem wenn man sie mit Hands-off-Maßnahmen kombiniert.
Arthrofibrose – Dehnen nicht erwünscht
Authors: Röhner Eric , Mayfarth Anke , Zippelius Timo
Published: September 2017

Langwierig und äußerst schmerzhaft: Patienten, die nach einer Operation oder Verletzung eine Arthrofibrose entwickeln, brauchen Geduld. Denn die Pathogenese der schmerzhaften Beweglichkeitseinschränkung ist noch ungeklärt, sodass man in der Therapie rein symptomatisch vorgeht. Die Physiotherapie spielt dabei die wichtigste Rolle.
Lösungsorientierte Beratung in der Physiotherapie – Die Wunderfrage!
Authors: Bark Sandra , Wache Thomas
Published: September 2017

Die klassische Zielfindung stößt bei Patienten, etwa in der Spätphase nach Schlaganfall, oft an ihre Grenzen. Eine Alternative bietet die Lösungsorientierte Beratung – eine psychotherapeutische Gesprächsführung, bei der der Therapeut mithilfe spezieller Fragen gemeinsam mit dem Patienten positiv in die Zukunft blickt und die Vergangenheit außer Acht lässt.
Miktionstagebuch – Die Blasen-Agenda
Authors: Köhler Barbara
Published: September 2017

Harnverlust, Ausscheidungsmenge, Einlagenwechsel, Harndrang und Trinkmenge doku- mentiert ein Patient in seinem Miktionstagebuch. So lassen sich Verhaltensänderungen besprechen, die Therapie planen und der Therapieerfolg beurteilen – ein Muss für einen professionellen Auftritt gegenüber Arzt und Patient.
Hausärztliche Versorgung in Deutschland – Gleicher Zugang für alle?
Authors: Bauer Jan , Maier Werner , Müller Ruth , Groneberg David
Published: September 2017

Hintergrund Ein gleichmäßiger Zugang zu hausärztlicher Versorgung spielt eine wesentliche Rolle bei der medizinischen Versorgung in Deutschland und ist daher Ziel der ambulanten Bedarfsplanung.

Ziel der Arbeit Mit der vorliegenden Arbeit sollen räumliche Aspekte des Zugangs zur hausärztlichen Versorgung untersucht und mit den Zielen der aktuellen Bedarfsplanung verglichen werden.

Material und Methoden Der räumliche Zugang zur hausärztlichen Versorgung wurde auf Basis der „integrated Floating Catchment Area“-Methodik unter Einsatz eines geografischen Informationssystems auf Ebene von Quadratkilometer-Zellen (Hektarzellen für Großstädte) gemessen („Zugangsindex“).

Ergebnisse Die Analyse von 649 Millionen generierten Datensätzen zeigte erhebliche geografische Variationen des Zugangs: 4,7 % der Gesamtbevölkerung leben in Gebieten mit signifikant niedrigerem hausärztlichen Zugang (z-Wert = –3,4) während 48,0 % in einem Gebiet mit signifikant höherem hausärztlichen Zugang leben (z-Wert = 9,7). Der durchschnittliche Zugangsindex lag bei 0,14 (SD = 0,15) und war umso höher, je urbaner das Gebiet (r = 0,64; p < 0,001) und je geringer der Grad der regionalen Deprivation war (r = –0,37; p < 0,001). Innerhalb der Bedarfsplanungsregionen variierte der Zugangsindex um durchschnittlich Δ = 0,23 (SD = 0,19) und korrelierte nicht mit dem hausärztlichen Versorgungsgrad (r = –0,04; p = 0,28).

Diskussion Bezüglich des Zugangs zu hausärztlicher Versorgung bestehen in Deutschland Stadt-Land-Disparitäten sowie soziale Ungleichheit im Sinne regionaler Deprivation. Aus diesem Grund sollte die Bedarfsplanung zukünftig räumliche Aspekte des Zugangs wie Erreichbarkeit und Verfügbarkeit stärker berücksichtigen.
Does Intensive Soccer Playing During the Growth Period Lead to Leg Length Discrepancies?
Authors: Guer Jean-Luc , Blanchard Sylvain , Harnagea Marta , Lopez Eric , Behr Michel
Published: September 2017

Leg length discrepancies (LLD) are a common reason for podiatry consultations and can affect up to 90% of the overall population. Furthermore, it is widely recognized that intensive participation in certain sports can alter bone development. The aim of this study is to explore any possible relation between playing soccer and the appearance or evolution of LLD, by means of a retrospective study based on the analysis of case reports of patients followed for foot or plantar troubles. Case reports were selected in the archives of a podiatric clinic for the period between 2002 and 2016 among patients who declared regular to intensive soccer playing, aged 13 years or more. LLD was detected in the vast majority of cases (95 cases out of 104). Pearson correlation coefficients were computed and revealed a strong correlation between the laterality of the kicking limb and that of the shorter leg. The shorter limb was on the side of the kicking leg in 96% of the cases when considering the players who began practice before the age of 13, and only 53% of the cases for others. Intensive soccer playing at a young age may encourage the appearance and evolution of a real LLD.
Semiconductor surface emitting lasers for photon pairs generation
Authors: Vanbever Luc R. , Karpov Evgueni , Panajotov Krassimir
Published: September 2017

We study the feasibility of generating photon pairs in a resonant Vertical-Cavity Surface-Emitting Laser (VCSEL) as a result of a third-order non-linear, four wave mixing interaction. We focus on degenerate four wave mixing in the spontaneous regime where two pump photons are annihilated to create a pair of signal and idler photons. Using the methods of quantum optics, we calculate the two-photon production rate, the spectrum of the generated photons, and the signal-idler cross-correlations. We highlight how the dispersion of the medium in the VCSEL cavity (a regular GaAs configuration) significantly diminishes the two-photon production rate. Based on our results, we enumerate the characteristics of a VCSEL that would be suitable for photon pair generation.