bluuebunny/crossref_metadata_2025 huggingface dataset:
Vaccine Potency and Structure of Yeast-Produced Polio Type 2 Stabilized Virus-like Particles
Authors: Hong Qin , Wang Shuxia , Wang Xiaoli , Han Wenyu , Chen Tian , Liu Yan , Cheng Fei , Qin Song , Zhao Shengtao , Liu Qingwei , Cong Yao , Huang Zhong
Published: September 2024

Poliovirus (PV) is on the brink of eradication due to global vaccination programs utilizing live-attenuated oral and inactivated polio vaccines. Recombinant PV virus-like particles (VLPs) are emerging as a safe next-generation vaccine candidate for the impending polio-free era. In this study, we investigate the production, antigenicity, thermostability, immunogenicity, and structures of VLPs derived from PV serotype 2 (PV2) wildtype strain and thermally stabilized mutant (wtVLP and sVLP, respectively). Both PV2 wtVLP and sVLP are efficiently produced in Pichia pastoris yeast. The PV2 sVLP displays higher levels of D-antigen and significantly enhanced thermostability than the wtVLP. Unlike the wtVLP, the sVLP elicits neutralizing antibodies in mice at levels comparable to those induced by inactivated polio vaccine. The addition of an aluminum hydroxide adjuvant to sVLP results in faster induction and a higher magnitude of neutralizing antibodies. Furthermore, our cryo-EM structural study of both sVLP and wtVLP reveals a native conformation for the sVLP and a non-native expanded conformation for the wtVLP. Our work not only validates the yeast-produced PV2 sVLP as a promising vaccine candidate with high production potential but also sheds light on the structural mechanisms that underpin the assembly and immunogenicity of the PV2 sVLP. These findings may expedite the development of sVLP-based PV vaccines.
The Diagnostic Value of qPCR Quantification of Paenibacillus larvae in Hive Debris and Adult Bees for Predicting the Onset of American Foulbrood
Authors: Papić Bojan , Žvokelj Lucija , Pislak Ocepek Metka , Hočevar Barbara , Kozar Monika , Rus Rene , Zajc Urška , Kušar Darja
Published: September 2024

American foulbrood (AFB) is a serious infectious disease of honeybees (Apis mellifera) caused by Paenibacillus larvae. Increased P. larvae count in hive-related material is associated with an increased risk of AFB. Here, we quantified P. larvae cells in 106 adult bee and 97 hive debris samples using quantitative PCR (qPCR); 66/106 adult bee and 66/97 hive debris samples were collected simultaneously from the same bee colony (paired-sample design). The corresponding bee colonies were also examined for the presence of AFB clinical signs. A binary logistic regression model to distinguish between AFB-affected and unaffected honeybee colonies showed a strong diagnostic accuracy of both sample types for predicting the onset of AFB based on P. larvae counts determined by qPCR. The colonies with a P. larvae count greater than 4.5 log cells/adult bee or 7.3 log cells/mL hive debris had a 50% probability of being clinically affected and were categorized as high-risk. The AFB-unaffected colonies had significantly lower P. larvae counts than the AFB-affected colonies, but the latter did not differ significantly in P. larvae counts in relation to the severity of clinical signs. Both bee-related sample types had a high diagnostic value for predicting disease outcome based on P. larvae counts. These results improve the understanding of the relationship between P. larvae counts and AFB occurrence, which is essential for early detection of high-risk colonies.
The 2021 Kansas Rural Grocery Survey: Revaluating Extension’s role in rural grocery issues
Authors: Miller-Klugesherz Jacob , Ramirez Jessica , Carver Rial , Blair Erica , Tsoodle Leah , Schufler Lauren
Published: September 2024

Kansas State University’s Rural Grocery Initiative, housed under research and extension, surveyed rural Kansas grocery stores in 2021 (N = 48). This is the second RGI survey, following up on the ownership and customer surveys in 2008. This survey broadly assesses owner characteristics, store features, and challenges. Using descriptive and thematic analyses, we identified two topline conclusions for grocers and their respective Extension services. First, grocers need to identify transition plans earlier and more often. Second, grocers can overcome competition and distribution challenges by diversifying their sourcing, supply, and offerings.
Comparing Participant Recruitment Methods for Statewide Needs Assessment Surveys
Authors: Harder Amy , Craig Diane , Leitheiser Karlibeth
Published: September 2024

Contracting with a paid survey vendor can be costly; are free and low-cost survey recruitment methods a sound option for Extension? The purpose of our study was to assess the feasibility of using free or low-cost recruitment methods as a substitute for contracting with a paid survey vendor when conducting a statewide needs assessment. The demographic characteristics and responses from paid survey panelists were compared with the same data from participants recruited via Facebook, Twitter, and LinkedIn. Observed differences suggest that Extension professionals should carefully consider whose perspectives are needed for a needs assessment and make survey recruitment decisions accordingly.
A Case Study: Do You Address Your Volunteers’ Well-Being or Mental Health During the COVID-19 Pandemic? If So, How?
Authors: Robotham Daniel , Windon Suzanna , Echols Ann
Published: September 2024

The uncertainty caused by the COVID-19 pandemic had a profound negative impact on volunteer mental health and well-being. We surveyed local non-profit organizational leaders about their practices toward addressing volunteer well-being and mental health during the COVID-19 pandemic. Study results indicated that while over a quarter of organizations did nothing to address volunteer well-being, other organizations utilized several approaches, including one-on-one and group meetings, program implementation, office culture investment, task assignment, and information dissemination. These findings provide valuable insight for Extension educators to develop community mental health and well-being programs to assist non-profit organizations' response to future uncertainty.
Applying the 5Ps of Cultural Ecosystem Services for Urban Agricultural and Natural Resources Programming
Authors: Gonzalez Mayra
Published: September 2024

Beyond adapting extension programs for an urban audience, Urban Extension strives to reach an underserved audience that hugely overlaps with marginalized populations. This means that cultural competence is crucial for successful program implementation. The following article outlines the application of the 5P framework of Cultural Ecosystem Services as a tool for laying out the base to a culturally competent extension program. Although originally intended for urban planners, when applied widely for program development it allows accounting for place, past, people, practices, and purposes in a simple manner without overlooking importance context pertaining the target audience.
Building Gender Equity in Forestry Education: The benefits of Oregon’s Women Owning Woodlands Network
Authors: Grand Lauren , Hopkins Tiffany
Published: September 2024

The Women Owning Woodlands Network was launched in 2005 as a way to provide collaborative and hands-on peer learning education to women who felt uncomfortable participating in traditional Extension programs. Since its inception the program as grown to provide education and resources for over 300 women. We surveyed these women to identify if the program continues to meet their needs. It is evident that WOWNet has continued to be an important part of OSU FNR’s outreach education program and continues to meet the needs of a historically undeserved group of landowners in ways that traditional programming does not.
Collaborating for Social Change: Promising Practices for Effective Youth-Adult Partnerships
Authors: Kokozos Michael , Gonzalez Maru
Published: September 2024

Youth-adult partnerships are a powerful means to nurture and amplify youths' voices and create social change. Drawing on our own framework, critical positive youth development, and our experience pilot testing the #PassTheMicYouth curriculum, we identified four promising practices to cultivate youth-adult partnerships. 4-H professionals can use these strategies with youths to prepare them to partner with community-based organizations and to maintain enduring and effective relationships.
Adoption of Podcasting as a Tool for Extension Educators
Authors: Bennett Samantha , Martin David , Sawyer Jason , Rodning Soren , Mulvaney Don
Published: September 2024

The current study fills a gap in the current literature by measuring current CES personnel and stakeholders’ attitudes toward the use of Podcasts as a tool for information dissemination. By identifying perceived barriers to podcasts by CES personnel and how receptive CES stakeholders are to CES-based podcasts, this study helps to identify important barriers to the development of podcasts, as well as how such podcasts can be best positioned to fulfill the needs and expectations of CES stakeholders. Podcasts have the potential to play a key role as an avenue for information exchange between the CES and its stakeholders. Two separate surveys were employed, one which focused on CES personnel with the second study focusing on CES stakeholders. Participant recruitment took place through email and data analyses utilized SPSS to conduct descriptive statistics and frequencies. Findings indicate that significant difference exist between CES personnel and CES stakeholders when it comes to attitudes and beliefs regarding podcasts as a CES tool.
Nörodejeneratif Hastalıklarda Yeni Bir Yaklaşım: Mitokondri Hedefli Tedavi
Authors: Çelik Kübra , Taşkıran Dilek
Published: September 2024

Mitokondri hücrenin enerji metabolizmasında, oksidatif fosforilasyonda ve hücre ölümünde rol alan temel organeli olup pek çok hastalıkta olduğu gibi nörodejeneratif hastalıkların da patogenezine katkı sağlar. Günümüzde çoğu nörodejeneratif hastalığın etiyopatogenezinde reaktif oksijen ve nitrojen türlerine bağlı oksidatif hasar sorumlu tutulmakla birlikte antioksidan tedaviler bu hasarın önlenmesi ve iyileştirilmesi konusunda yeterli olmamaktadır. Bu nedenle son yıllarda mitokondriyi direkt olarak hedefleyen ve içerisinde biriken farklı farmakolojik ajanlar geliştirilmiş olup birçok nörodejenerasyon hayvan modelinde iyileştirici etkileri görülmüştür. Aynı zamanda bu ajanlardan bazılarının insan klinik çalışmalarında güvenilir ve etkili olduğu kanıtlanmıştır. Bu derlemede, Alzheimer ve Parkinson hastalıkları başta olmak üzere nörodejeneratif hastalıklarda mitokondri disfonksiyonu ve bu hastalıkların tedavisinde etkili olacağı düşünülen mitokondri hedefli tedavi ile ilgili güncel bilgiler tartışılmıştır.
Üreme Çağı Kadınların Sağlıklı Yaşam Biçimi Davranışları ile Üreme Sağlığını Koruyucu Tutumları Arasındaki İlişki
Authors: Kara Pınar
Published: September 2024

Amaç: Üreme sağlığı göstergeleri, bir toplumun genel ve sosyal sağlığının en önemli belirleyicilerinden biri olup, kadınların yaşamlarını doğrudan etkileyen öneme sahiptir. Bu nedenle bu araştırma, üreme çağı kadınların sağlıklı yaşam biçimi davranışları ile üreme sağlığını koruyucu tutumları arasındaki ilişkinin belirlenmesi amacıyla yapılmıştır.
Yöntem: Kesitsel ve ilişki arayıcı tipteki araştırma, Aralık 2023-Ocak 2024 tarihleri arasında Türkiye’nin güneydoğusundaki bir ilin devlet hastanesinde üreme çağındaki 247 kadınla gerçekleştirilmiştir. Veriler, veri toplama formu, “Sağlıklı Yaşam Biçimi Davranışları Ölçeği (SYBDÖ) II” ve “Evli Kadınların Üreme Sağlığını Koruyucu Tutumlarını Belirleme Ölçeği (ÜSBÖ)” kullanılarak toplanmıştır.
Bulgular: Katılımcıların yaş ortalaması 31.16±8.70 olup, çoğunluğu (%35.6) 35 yaş ve üzerindedir. Kadınların BKİ ortalaması 25.68±3.97 kg/m2 ve %44.5’i normal kilodadır. Çoklu doğrusal regresyon analizinde, SYBDÖ II’nin fiziksel aktivite, sağlık sorumluluğu ve manevi gelişim altboyutları ile ÜSBÖ toplam puanı arasında istatistiksel olarak anlamlı bir ilişki olduğu belirlenmiştir (p
Investigation of Clinical Features and Comorbid Psychopathologies of Children with Sleep Terrors
Authors: Şireli Özlem , Uzun Çiçek Ayla , Abanoz Elif , Ucuz İlknur , Naralan Yüksel Sümeyra
Published: September 2024

Aim: In this study, it was aimed to investigate the clinical characteristics of children diagnosed with sleep terrors, including sleep environment and sleep habits, clinical features and comorbid psychiatric disorders.
Method: Between 2020 and 2024, 51 children who were diagnosed with sleep terror according to DSM-5 diagnostic criteria in 3 different Child and Adolescent Psychiatry clinics were included in the study. The sociodemographic and clinical characteristics of the cases were examined retrospectively through the files.
Results: Of the 51 participants, 30 (58.8%) were male, 21 (41.2%) were female and the mean age at the time of admission was 6.76±1.45 years. It was determined that 15 (29.4%) of the cases slept in a noisy environment and 41 (80.4%) of the cases had their sleep interrupted except for sleep terror attacks. At least one psychiatric disorder was detected in 17 (33.3%) patients, and the most common (9.8%) comorbid psychiatric disorder was attention deficit hyperactivity disorder. It was found that complete retrograde amnesia was significantly higher in preschoolers, and motor activity during the attack, physical injury and/or material damage, and full awakening during the attack were significantly higher in school-age children. It was determined that 64.7% of the parents intervened incorrectly during the episode, and in 29.4% of the cases, the wrong medication was applied in the treatment history.
Conclusion: In sleep terrors, identification of triggering factors and comorbid psychiatric disorders during the diagnostic evaluation process, psychoeducation of parents in treatment, and selection of appropriate medication for medication are very important.
The Effect of Helfer Skin Tap Technique on Pain Reduction and Hemodynamic Parameters During Tetanus Injection in Pregnant Women
Authors: Baysal Ebru , Karakuş Selçuk Aslı , Kişlali Taş Şeyma
Published: September 2024

Abstract
Aim; The study was aimed at determining the effect of the Helfer skin tap technique on pain reduction and hemodynamic variables in pregnant women during tetanus injection.
Method; It was a comparative study with a randomized control group conducted in a Family Health Center between August 2021, and March 2022. The study was conducted with 65 pregnant women who got tetanus vaccine. The tetanus vaccine was administered using the Helfer skin tap techniques to 33 of pregnant women and the standard intramuscular injection (IM) technique to 32 women. Pregnant women’s pain levels were evaluated on the Number Rating Scale after vaccination by the researcher. Similarly, the hemodynamic variables of the pregnant women were examined by the same researcher before and immediately after the vaccine administration.
Results; It was determined that there was a statistically significant difference between the Helfer skin tap groups and standard application group in terms of mean pain intensity in the post-intervention (p < .01). The majority of the sample (69.7%) in the Helfer skin tap group perceived mild pain and most of the participants (46.9%) in the standard application group had moderate pain in the post-intervention. Respiratory rates of the pregnant women in the Helfer skin tap group were seen to decrease significantly after the vaccine administration (p < .01), but no change was found in the other hemodynamic variables. Helfer skin tap group heart rates were significantly lower compared with those in the standard group (p < .05), while their saturation levels were significantly higher (p < .01).
Conclusion; It was concluded that the Helfer skin tap technique is an effective method to reduce pain during IM tetanus vaccine administration.
Navigating Latency-Inducing Viral Infections: Therapeutic Targeting and Nanoparticle Utilization
Authors: Vasukutty Arathy , Jang Yeonwoo , Han Dongwan , Park Hansoo , Park In-Kyu
Published: September 2024

The investigation into viral latency illuminates its pivotal role in the survival strategies of diverse viruses, including herpesviruses, HIV, and HPV. This underscores the delicate balance between dormancy and the potential for reactivation. The study explores the intricate mechanisms governing viral latency, encompassing episomal and proviral forms, and their integration with the host’s genetic material. This integration provides resilience against cellular defenses, substantially impacting the host–pathogen dynamic, especially in the context of HIV, with implications for clinical outcomes. Addressing the challenge of eradicating latent reservoirs, this review underscores the potential of epigenetic and genetic interventions. It highlights the use of innovative nanocarriers like nanoparticles and liposomes for delivering latency-reversing agents. The precision in delivery, capacity to navigate biological barriers, and sustained drug release by these nanocarriers present a promising strategy to enhance therapeutic efficacy. The review further explores nanotechnology's integration in combating latent viral infections, leveraging nanoparticle-based platforms for drug delivery, gene editing, and vaccination. Advances in lipid-based nanocarriers, polymeric nanoparticles, and inorganic nanoparticles are discussed, illustrating their potential for targeted, efficient, and multifunctional antiviral therapy. By merging a deep understanding of viral latency’s molecular underpinnings with nanotechnology’s transformative capabilities, this review underscores the promise of novel therapeutic interventions. These interventions have great potential for managing persistent viral infections, heralding a new era in the fight against diseases such as neuroHIV/AIDS, herpes, and HPV.
REPRODUCTIVE HEALTH OPTIMIZATION: REMARKABLE BENEFITS OF AVOCADO JUICE IN ENHANCING PRODUCTION AND REDUCING SPERMATOZOAL ABNORMALITIES IN MICE EXPOSED TO CLOVE CIGARETTE SMOKE
Authors: Kaihena Martha , Ukratalo Abdul M , Pangemanan Victory O , Manery Dodikrisno E
Published: September 2024

Cigarette smoke has the potential to disrupt hormonal balance, affect spermatogenesis processes, impair spermatozoa viability, and introduce toxic substances to spermatozoa. Avocado fruit contains proteins and vitamins such as vitamin A, B, B1, B2, E, and C, beta-carotene, linoleic acid, lecithin, calcium, iron, pantothenic acid, potassium, phosphorus, niacin, and natural plant oils. The presence of vitamin C and E in avocado is believed to enhance the quantity of Leydig cells and spermatozoa. This study aims to evaluate the potential of avocado juice in optimizing reproductive health in mice exposed to clove cigarette smoke. Male mice (Mus musculus), aged 2 months, weighing ±20g, were randomly divided into 5 groups: K- (negative control), K+ (positive control exposed to cigarette smoke without avocado juice), P1 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.5 ml/20 g BW), P2 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.7 ml/20 g BW), and P3 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.9 ml/20 g BW). Cigarette smoke exposure was administered for 14 days. The results indicate that regular avocado juice consumption can enhance sperm production and reduce spermatozoa abnormalities in mice exposed to clove cigarette smoke. The clinical implications of these findings contribute to a deeper understanding of the potential of avocado juice as a supplement to improve reproductive health, particularly in environments exposed to clove cigarette smoke
THE POTENTIAL OF ETHANOL EXTRACT FROM LANGSAT LEAVES (Lansium domesticum Var. Pubescent) IN CONTROLLING Aedes aegypti MOSQUITOES: A STUDY ON THE EFFECTIVENESS OF NATURAL SUBSTANCES AS MOSQUITO REPELLENTS
Authors: Ukratalo Abdul M , Ichsan Muhammad Nurhidayat , Kaihena Martha , Manery Dodikrisno Ekaputra , Manery Dodikrisno Ekaputra , Pangemanan Victory Osvaldo , Moniharapon Debby Dijola
Published: September 2024

The spread of diseases caused by the Aedes aegypti mosquito, such as dengue fever and Zika fever, continues to pose a serious threat to public health in many countries, particularly in tropical and subtropical regions. In an effort to address this problem, vector control is a key part of the strategy to prevent the transmission of these diseases. In recent decades, attention to the utilisation of natural materials as alternatives in vector control has increased. One potential source that needs to be explored is langsat leaves, which are known to have active compounds. Ethanol extracts of langsat leaves may contain compounds that can provide control effects against Aedes aegypti mosquito larvae. This study aims to assess the effectiveness of ethanol extract of langsat leaves in controlling Aedes aegypti mosquitoes, the vector of Dengue Fever disease. The extraction method was carried out using maceration technique with ethanol solvent. Bioactivity test was conducted through larvicidal bioassay against Aedes aegypti larvae. The results showed that ethanol extract of langsat leaves has larvicidal effect against Aedes aegypti mosquito larvae. The toxicity levels, both LC50 and LC90, indicate that the ethanol extract of langsat leaves has potential as a mosquito larvae control agent.
Sandra Bullock, chiński pojazd kosmiczny i matematyka
Authors: Kordos Marek
Published: September 2024

O geometrii
Diagnoza użytkowania karabinków MSBS GROT w wojnie w Ukrainie w okresie roku jej trwania. Wybrane aspekty
Authors: Sztobryn Marcin
Published: September 2024

W okresie roku prowadzenia wojny w Ukrainie strona rosyjska poniosła nienotowane dotąd straty w potencjale ludzkim. Jest to olbrzymia liczba, świadcząca także o wykorzystaniu na skalę masową urządzeń i sprzętu wojskowego. W czasie trwania tej wojny strona ukraińska stosowała broń będącą na jej wyposażeniu oraz dostarczoną przez państwa sprzymierzone. Jednym z największych donatorów uzbrojenia stała się Polska. Strona ukraińska otrzymała z polskich zasobów modułowy karabinek MSBS GROT, którego całościowy proces konstruowania i wytwarzania przebiega w Fabryce Broni „Łucznik” w Radomiu. Dotychczas karabinek ten najczęściej wykorzystywały Wojska Obrony Terytorialnej, a w późniejszym czasie wojska operacyjne RP. Żołnierze jednomyślnie podkreślają, że to dobra, prosta i wygodna w obsłudze broń, a jej użytkowanie staje się wręcz intuicyjne. Praktyczne sprawdzenie karabinka w realnych działaniach zbrojnych w Ukrainie wpłynęło na zainteresowanie tym rodzajem broni.
„Być Andrzejem Małkowskim swoich czasów” – historia i dziedzictwo polskiego skautingu oraz problem wartości harcerskich w „Bratnim Słowie” w latach 1980–1981
Authors: Gawriłow Michał
Published: September 2024

Problem poglądów Kręgów Instruktorów Harcerskich im. Andrzeja Małkowskiego na temat znaczenia tradycji i historii ruchu harcerskiego oraz odnowy ideowej ZHP poruszanych w artykułach opublikowanych w czasopiśmie „Bratnie Słowo” w latach 1980-1981 nie był dotychczasomawiany w nauce polskiej. Artykuł stawia sobie za cel rekonstrukcję tego zagadnienia w perspektywie ogólnej kondycji Związku Harcerstwa Polskiego w początku lat 80. XX w.
Judicial Resistance: missing part of Judicial independence? The case of Poland and beyond
Authors: Bojarski Lukasz
Published: September 2024

This article critically examines the concept of "judicial resistance" in Poland between 2015-2023, drawing insights from both Polish and international legal frameworks, jurisprudence, empirical research and literature. The study aims to define and differentiate judicial resistance from other judicial attitudes, interrogate its legal character, and explore whether there exists judges’ right or duty towards such resistance. The article posits a definition for judicial resistance, emphasizing actions—both collective and individual, in-court and out-of-court—taken by judges to counter political endeavors that infringe upon judicial independence and violate the law. A pivotal criterion proposed is that the breach of judicial independence must be illegitimate as per national standards and validated as such. To support this, the article references formal assessments from both national and international bodies. The findings indicate a potential necessity for a broader conceptualization of judicial resistance, suggesting it as a possible safeguard against future erosions of the rule of law.
Beyond Rationality: Exploring Neoclassical, Behavioral, and Austrian Approaches to Finance
Authors: Marion Ceolin Artur , Rossi Mazzoni João Fernando
Published: September 2024

This paper compares neoclassical, behavioral, and Austrian perspectives on financial behavior, focusing on market conception, asset pricing, and portfolio organization. Neoclassicals emphasize efficient markets and risk-averse, diversified portfolios. Behavioral finance highlights psychological biases influencing investment decisions but overlooks the role of reflection and external economic factors. On the other hand, the Austrian perspective views markets as dynamic processes driven by rational human actions, where individuals learn and adapt. Austrians critique neoclassical reliance on historical data and the behavioral perspective’s overemphasis on biases, advocating for a subjective approach to asset valuation and portfolio design. The article argues for an Austrian investment theory, emphasizing purposeful actions, learning, and individual judgment under uncertainty, contrasting with the static neoclassical and behavioral finance models. This work contributes to a systematic framework for comparing these schools and offers a new critique of behavioral finance from an Austrian perspective.
Yes, You Should Own Bitcoin
Authors: Slutskiy Pavel
Published: September 2024

This article attempts to challenge the argument that bitcoin cannot be owned within a libertarian legal order. According to the contested view, bitcoin, as a digital asset, does not meet the criteria for traditional ownership due to its nonphysical nature as an intangible asset. However, the counterargument presented in the article asserts that people should have property rights over bitcoin due to the facts that the technology behind bitcoin makes it a scarce rivalrous resource and conflicts over the use of bitcoin goods can arise. It is the general function of property rights to avoid possible clashes over the use of scarce, rivalrous resources by assigning rights of exclusive ownership; hence, property rights should extend to bitcoin. The article also discusses the implications of recognizing bitcoin as an ownable scarce resource within a private law society and addresses the challenges associated with penalizing bitcoin theft.
Relationship between organophosphate and pyrethroid pesticides and metabolic syndrome in Korean farmers
Authors: Kim Sungbeom , Roh Sangchul , Kim Min-Gi , Rhie Jeongbae , Yoon Jisue , Moon Sun-In
Published: September 2024

Background: The global use of pesticides steadily increased until the early 2010s. Pesticides play a significant role in agriculture in Korea. Metabolic syndrome is more prevalent in rural areas than in urban areas. This study explored the potential association between organophosphate and pyrethroid pesticide exposure and metabolic syndrome.Methods: This study enrolled 1,317 individuals who participated in the Pesticide Exposure and Intoxication Study conducted by the Dankook University Hospital Center for Farmers’ Safety and Health from 2014 to 2019. Urinary levels of dimethylphosphate, dimethylthiophosphat, diethylphosphate, and diethylthiophosphate were measured to assess organophosphate pesticide exposure and urinary levels cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid, cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylic acid, and 3-phenoxybenzoic acid were measured to assess pyrethroid pesticide exposure.Results: The odds ratio for the 4th quartile group of organophosphate metabolites concentration was 1.48 (95% confidence interval: 1.06–2.09) compared to the 1st quartile group after adjustment for general factors. In addition, a positive trend was observed across the quartile groups of organophosphate metabolites concentration. A positive trend was noted across the quartile groups of organophosphate metabolites in males, while no significant association was observed in females. Furthermore, no significant associations were observed between metabolic syndrome and pyrethroid metabolites concentration.Conclusions: A positive correlation was observed between the prevalence of metabolic syndrome and the concentrations of urinary organophosphate metabolites, consistent with previous research finding. This association may be attributed to the action of organophosphates as acetylcholinesterase inhibitors, stimulating beta cells in the islets of Langerhans. This can lead to alterations in lipid metabolism and insulin resistance, ultimately leading to metabolic syndrome development. Metabolic syndrome is a major contributor to cardiovascular disease; therefore, it is necessary to identify the risk factors unique to rural areas, such as pesticide exposure.
NUTRITIONAL AND ENERGY VALUE OF MUSCLE TISSUE OF BULLS OF SPECIALIZED MEAT BREEDS IN PRIMORSKY KRAI
Authors: Косилов В.И. , Толочка В.В. , Миронова И.В. , Никонова Е.А. , Тимербулатова Р.Г. , Кадиров Н.Н. , Алексеев О.В.
Published: September 2024

В статье приводятся результаты влияния генотипа бычков калмыцкой (I группа), абердин-ангусской (II группа) и герефордской пород (III группа) на показатели длиннейшей мышцы спины, такие как химический состав, энергетическая ценность и выход питательных веществ мышечной ткани туши. Бычки абердин-ангусской породы демонстрировали преимущество по пищевой и энергетической ценности мышечной ткани по сравнению с бычками калмыцкой и герефордской пород. Так, у абердин-ангуссов массовая доля сухого вещества в длиннейшей мышце спины была выше на 2,41 и 1,31% соответственно, экстрагируемого жира – на 1,22 и 0,89%, протеина – на 1,02 и 0,31%, концентрации энергии в 1 кг мышечной ткани – на 650,13 кДж (15,12%) и 399,76 кДж (8,79%), энергетической ценности всей мышечной ткани туши – на 106,30 мДж (29,40%) и 25,24 мДж (5,70%) по сравнению с калмыцкими и герефордскими аналогами. Минимальной пищевой и энергетической ценностью отличалась мышечная ткань бычков калмыцкой породы.

The article provides the results of the influence of the genotype of the bulls of Kalmyk (I group), Aberdeen Angus (group II) and Hereford breeds(group III) on the indicators of the longest back muscles, such as the chemical composition, energy value and nutrient yield of carcass muscle tissue. The bulls of the Aberdeen Angus breed showed the advantage in the nutritional and energy value of muscle tissue compared to Kalmyk and Hereford bulls. So, in Aberdeen Angusses, the mass fraction of the dry matter in the longest back muscle was higher by 2.41 and 1.31%, respectively, extractable fat – by 1.22 and 0.89%, protein – by 1.02 and 0.31%, energy concentrations in 1 kg of muscle tissue – by 650.13 kJ (15.12%) and 399.76 kJ (8.79%), energy value of the entire muscle tissue of the carcass – by 106.30 MJ (29.40%) and 25.24 MJ (5.70%) compared to Kalmyk and Hereford analogues. The muscle tissue of the Kalmyk bulls was characterized by minimal nutritional and energy value.
ECOLOGICAL AND GENETIC ADAPTATION STRATEGY OF SOME INVASIVE HYDROBIONT SPECIES
Authors: Слынько Е.Е. , Белкин Е.Н. , Климкин С.В.
Published: September 2024

Проведены молекулярно-генетические и морфологические исследования рапаны Rapana venosa (Valenciennes, 1846) крымской акватории Чёрного моря с целью определения возможных причин инвазионного успеха этого моллюска. Молекулярно-генетический анализ проводили по гену COI в сравнении с данными по исходным и другим инвазионным популяциям. Полностью подтверждён необычайно низкий уровень генетической изменчивости рапаны в Чёрном море, однако в естественных популяциях Жёлтого, Восточно-Китайского и Японского морей её генетическая изменчивость весьма высокая. Показано, что большое значение в расселении рапаны имеет внутривидовое морфо-экологическое формообразование. У Rapana venosa крымской акватории Чёрного моря выявлены две морфо-экологические формы, связанные с особенностями развития пропорций раковины.

Molecular genetic and morphological studies of rapa whelk Rapana venosa (Valenciennes, 1846) of the Crimean Black Sea were carried out in order to determine the possible reasons for the invasive success of this mollusk. Molecular genetic analysis was carried out by COI gene in comparison with the data on initial and other invasive populations. The unusually low level of genetic variability of rapa whelk in the Black Sea is fully confirmed, however, in the natural populations of the Yellow, East China seas and Sea of Japan, its genetic variability is very high. It has been shown that intraspecific morpho-ecological formation is of great importance in the settlement of rapa whelk. Rapana venosa of the Crimean Black Sea has two morpho-ecological forms associated with the peculiarities of the development of shell proportions.
INCUBATION OF STURGEON ROE USING AN ELECTROSTATIC FIELD
Authors: Шмигель В.В. , Жолудева В.В. , Кутина А.Д.
Published: September 2024

В данной статье на основе статистических методов проведено сравнение доли выхода личинок при инкубации икры в аппаратах Вейса без наложения электростатического поля и доли выхода личинок с наложением электростатического поля через систему электродов. На основе t-критерия Стьюдента проверена гипотеза о схожести (различии) результатов вылупления личинок стерляди в контрольной и экспериментальной группах. Результаты проверки позволили сделать вывод об эффективности наложения электростатического поля через систему электродов, что позволяет существенно снизить потери личинок.

In this article, based on statistical methods, a comparison was made of the proportion of larval yield during incubation of roe in Weiss apparatus without application an electrostatic field and the proportion of larval yield with application an electrostatic field through a system of electrodes. Based on Student's t-test, the hypothesis of similarity (difference) in the results of hatching of sterlet larvae in the control and experimental groups was tested. The test results made it possible to conclude that the application of an electrostatic field through the electrode system is effective, which can significantly reduce the loss of larvae.
SIMULADORES DE CHUVAS: CONVERGÊNCIA ENTRE PARÂMETROS CIENTÍFICOS E DE USO NA REPLICAÇÃO DA PRECIPITAÇÃO NATURAL
Authors: Confessor Jefferson Gomes , Silva Lara Luíza , Rodrigues Silvio Carlos
Published: September 2024

A natureza infrequente das chuvas, imprevisibilidade dos eventos, duração, intensidade e erosividade variável torna o processo de aquisição de dados oriundos de chuvas naturais um trabalho complexo, dificultando e até inviabilizando a execução de estudos científicos. Simuladores de chuvas surgem neste contexto como forma de contornar esta problemática, os quais buscam replicar da maneira mais fiel possível eventos de precipitação natural de maneira artificial. Para garantir maior confiabilidade de uso, parâmetros científicos foram traçados, regulando os princípios básicos dos atributos a serem replicados por estes equipamentos. Além disso, a utilização de simuladores de chuvas também deve assegurar as demandas próprias de cada pesquisa, influenciando na gama variada de modelos de equipamentos encontrada na literatura, os quais utilizam-se de distintos mecanismos para formação e distribuição da precipitação, cada qual desenvolvido para sanar as problemáticas específicas de cada pesquisa. Neste sentido, este trabalho tem por objetivo apresentar os princípios básicos de funcionamento, usos, vantagens e desvantagens da utilização de diferentes modelos de simuladores de chuvas, de maneira a corroborar para o processo de compreensão de seu funcionamento e auxiliar na escolha do equipamento que melhor se adeque às demandas de cada pesquisa, contribuindo assim para melhoria da qualidade dos dados produzidos.
STUDI LITERATUR: MODEL PEMBELAJARAN DISCOVERY LEARNING DALAM MENINGKATKAN HASIL BELAJAR PESERTA DIDIK PASCA PANDEMI COVID-19
Authors: Hasanah Laeny Siti
Published: September 2024

Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar melalui model pembelajaran Discovery Learning sebagai inovasi pembelajaran yang dapat diterapkan oleh pendidik pasca pandemik Covid-19. Melalui kajian pustaka, metode “library research” analisis literatur digunakan dalam penelitian ini untuk melengkapi analisis terhadap berbagai sumber yang digunakan. Perumusan pertanyaan penelitian di awal penelitian dilanjutkan dengan penelaahan temuan penelitian terkait pelacakan jurnal terdahulu menggunakan artikel jurnal terindeks, buku, tesis, dan artikel online terkait penerapan Discovery Learning untuk mengumpulkan data kajian pustaka ini.  Hasil studi literatur menunjukkan bahwa Pasca pandemi Covid-19 yang terjadi di Indonesia penerapan strategi belajar mengajar dengan model Discovery Learning cukup berhasil guna meningkatkan hasil belajar siswa. Dari studi literatur yang telah dilakukan terungkap bahwa Discovery Learning sebagai model pembelajaran pasca Covid-19 berkontribusi dalam meningkatkan hasil akhir pembelajaran dan proses pengajaran para siswa.
VARIATIONAL THINKING AND ALGEBRAIC SYSTEMS IN 11TH GRADE
Authors: Martínez Zuleima Cardona , Mesa Fernando , Granada José Rodrigo González
Published: September 2024

This research focuses on identifying challenges in the acquisition of mathematical competencies related to variational thinking and algebraic and analytic systems among eleventh-grade students in Dosquebradas, Risaralda, Colombia. The main objective was to diagnose the level of these competencies and design an instructional intervention to enhance them. This research utilized a didactic sequence approach within the classroom setting, which demonstrated significant benefits for strengthening mathematical competencies. The findings revealed a low performance level in students' competencies, identified through Saber tests conducted by ICFES and diagnostic exercises. The research also underscored the importance of implementing strategies such as technology utilization and family support. The designed instructional intervention effectively visualized competency development, leading to observable progress in students' skills. Additionally, the study validated the difficulties in competency acquisition through a prior and posterior analysis of the didactic sequence, identifying areas for improvement. Recommendations include further research on didactic sequence development, involving teachers in exploring these strategies, and promoting curiosity and motivation in educational practices. This study serves as an initial step toward enhancing mathematical thinking and contributing to the improvement of educational standards in Colombia.
NONPARAMETRIC HOMOGENEOUSLY WEIGHTED MOVING AVERAGE – MOVING AVERAGE CONTROL CHART BASED ON SIGN STATISTIC
Authors: Talordphop Khanittha , Sukparungsee Saowanit , Areepong Yupaporn
Published: September 2024

Nonparametric control charts are a reliable and strong tool for evaluating a technique when the true distribution of a quality attribute under consideration is unknown. In the present investigation, a novel nonparametric homogeneously weighted moving average-moving average control chart based on the sign statistic (HWMA-MA-SN) is offered for identifying shifts in processing mean. The effectiveness of the suggested chart is tested under symmetrical distribution utilizing several individual and overall performance indicators based on average run length (ARL). According to the results of the investigation, the proposed chart is superior to the existing control charts, such as the MA (moving average) chart, the HWMA (homogeneously weighted moving average) chart, the HWMA-SN (homogeneously weighted moving average sign) chart, and the HWMA-MA (mixed homogeneously weighted moving average-moving average) chart. Applying the proposed control chart with the juice production information generated results that were acceptable with the research findings.
Interpolation Methods: A Study of Solving Annual Data into Quarterly and Monthly Data
Authors: Rotinsulu Tri Oldy , Radianto Elia
Published: September 2024

This study aims to analyse the effect of Export Value (EKS_US$) and Exchange Rate (KURS_US$) on Gross Domestic Product (GDP) as a proxy for economic growth in Indonesia using multiple linear regression based on interpolated monthly data from annual data. In this paper, it is also explained about calculation examples, quarterly and monthly data interpolation methods using data from the Central Bureau of Statistics, namely Indonesia's Gross Domestic Product (GDP) for 2021-2022 at constant 2010 prices. Based on the calculation results, using multiple linear regression of monthly data for the 2018-2022 period, it shows that the estimated model has the best estimator, which is indicated by the variables used, passing the diagnostic test in the form of Multicollinearity, Heteroscedasticity, Autocorrelation, Normality, and Linearity tests. This indicates that the estimator value of the observed data is able to represent the random behaviour of the actual data. However, everything returns to the researcher, at which stage will be chosen is greatly influenced by various factors and considerations of the researcher. Thus, at certain stages and situations, it is very open to researchers to use data interpolation, especially on all data that has flow characteristics, such as GDP data, export values, exchange rates and others.
Keywords:   Interpolated data; annual data; quarterly data; monthly data; diagnostic tests
Fully vertical AlN-on-SiC Schottky barrier diodes
Authors: Okumura Hironori , Imura Masataka , Miyazawa Fuga , Mainini Lorenzo
Published: September 2024

We demonstrated fully vertical Schottky barrier diodes (SBDs) that have a Si-doped AlN drift layer directly grown on an n-type 4H-SiC substrate by metal-organic CVD. The AlN SBD with a Ni anode showed a clear rectifying characteristic at 300–500 K and a rectification ratio of about 10–2. We found that the leakage current of the vertical AlN-on-SiC devices is affected by defects in the AlN drift layer and Schottky interface.
Проблема моббінгу та дискримінації в трудових відносинах
Authors: Гавриленко Наталія
Published: September 2024

В запропонованій статті автор розглядає проблеми дискримінації і мобінгу в трудовому колективі, як єдину систему. Автор представляє свої висновки на підставі аналізу діючого законодавства, виділяє аспекти його недосконалості. Висновки побудовані на вивченні та аналізі діючого законодавства, спеціальної літератури та судової практики. Автор пропонує шляхи вирішення існуючих проблем у вигляді модернізації діючого законодавства України.
Book Review: Study Of Useful Properties Of Some Coordination Compounds Containing Oximic Ligands by E. COROPCEANU, A. CILOCI, A. ȘTEFÎRȚĂ, I. BULHAC
Authors: Nedbaliuc Boris
Published: September 2024

The monograph STUDY OF USEFUL PROPERTIES OF SOME COORDINATION COMPOUNDS CONTAINING OXIMIC LIGANDS is a synthesis of the works of the Coordination Chemistry, Enzymology and Plant nutrition and water regime laboratories during the last two decades. The monograph consists of four chapters, accompanied by bibliographic sources.
The assessment of the nutrient content in the plants of the hybrid Sorghum bicolor x Sorghum sudanense harvested in different development stages
Authors: Țiței Victor , Coșman Sergiu , Cîrlig Natalia , Coșman Valentina , Guțu Ana , Mocanu Natalia , Cozari Serghei , Teleuță Alexandru , Garștea Nina
Published: September 2024

The article presents the results of the research aimed at evaluating the nutrient content in the leaves, stems and panicles of the hybrid sorghum x Sudan grass “SAȘM-4” plants harvested in different development stages. It has been determined that the leaves have a higher content of crude protein, crude fat, carotene, ash, calcium and phosphorus; the stems have a high content of crude cellulose, nitrogen-free extract and sugar; while the panicles are rich in starch, with high energy value. During the growing season, in all component parts, the content of dry matter increases, the concentration of proteins decreases and the content of cellulose and nitrogen-free extract essentially increases.
O fim está próximo
Authors: Pereira Leonardo Faustino
Published: September 2024

This article develops a comparative study of the publications on the official X social network profiles of congressmen Nikolas Ferreira and Magno Malta, which occurred during October 2022 and expressly mention the terms: God; faith; church; Christ; Jesus; Christian(s); prayer; Bible. The analysis aimed to understand how religious themes and representations were used during the second-round campaign of that year's election on social media by ultra-conservative activists. It is noteworthy that the choice of X as a data source was not accidental. Despite being less used in Brazil compared to networks like Instagram or Facebook, it is notorious both for the engagement of its members and its ability to create "viral" images and texts capable of shaping the debate on other networks. The qualitative analysis conducted here of the textual, imagistic, and audiovisual contents of the two mentioned profiles on the platform presented curious results. It was observed not only a high recurrence of the use of the terms but also a similarity in the content of the messages in which they appeared. It was noted that the digital communication strategies employed by the two profiles often presented anti-system representations and imaginaries. The data processing for the analysis was conducted using the IRAMUTEQ program, which was also used to create a word cloud and two similarity graphs, which synthesized the research results.
Linguistic Distinctiveness: Ọládè̩jọ Ò̀kédìjì’s Àjà Ló Le̩rù as a Reference
Authors: Olúgbàmílà Adégúnlẹ̀, O.
Published: September 2024

It has been a common practice for writers to employ certain features in their work to carve out a unique linguistic identity. This study, therefore, seeks to explore the language use of the novelist/playwright Ọládèjọ Òkédìjí, focusing on one of his novels, Àjà Ló Lẹrù. It is undeniable that Òkédìjí remains one of the most creative detective novelists who adopted the Yoruba language as his medium of art. Beyond his deep investigative prowess, his ability to use words to create lasting images in the minds of his readers is a distinctive quality that sets him apart from his contemporaries. Some of the literary devices explored in this study include imagery, internal monologue, hyperbole, loanwords, parallelism, repetition, personification, idioms, proverbs, irony, onomatopoeia, malapropism, and puns. This work adopts the general stylistics theory, which examines universal principles and mechanisms such as syntax, tone, and rhetorical devices that contribute to conveying meaning and emotion. Ultimately, our analysis reveals that the author’s work challenges contemporary writers of Yoruba detective novels to once again draw inspiration from the effective use of the Yoruba language, as exemplified by this novel.