bluuebunny/crossref_metadata_2025 huggingface dataset:
Resonant Auger Decay in Benzene
Authors: Karippara Jayadev Nayanthara , Jagau Thomas-C , Krylov Anna I.
Published: October 2024

We present ab initio calculations of the resonant Auger spectrum of benzene. In the resonant process, Auger decay ensues following the excitation of a core-level electron to a virtual orbital. Hence, resonant Auger decay manifests itself in the Auger spectrum by features with higher Auger electron energy compared to non-resonant decay. We apply equation-of-motion coupled-cluster (EOM-CC) methods to compute the spectrum in order to explain the main features in the experimental spectrum and to assess the capability and limitations of the available theoretical approaches. The results indicate that participator decay can be well described with the Feshbach–Fano approach based on EOM-CC wavefunctions in the singles and doubles (SD) approximation, but spectator decay is more difficult to describe. This is because the target states of spectator decay are doubly excited, resulting in the need to include triple excitations in the EOM-CC wave function. Resonant Auger decay in benzene is thus a challenging test case for EOM-CC theory. We examine the performance of different noniterative triple corrections to EOM-IP-CCSD and our numerical results highlight the need to include triple excitations iteratively.
Molecular Insights into the Adsorption of Deposit Control Additives from Hydrocarbon Fuels
Authors: Corral-Casas Carlos , Ayestarán-Latorre Carlos , Gattinoni Chiara , Brewer Mark , Karl Jörn , Dini Daniele , Ewen James P.
Published: October 2024

Deposits can reduce engine performance and increase emissions, particularly in modern direct-injection engines. Surfactants known as deposit control additives (DCAs) ad- sorb and self-assemble on the surface of deposit precursors to keep them suspended in the fuel. Here, we show how molecular simulations can be used to virtually screen the ability of surfactants to bind to a major class of carbonaceous deposits, polyaromatic hydrocarbons. We use molecular dynamics with the adaptive biasing force method to generate the potential of mean force as a function of the distance between the surfactants and model deposits in gasoline and diesel fuel surrogates. We find that a zwitterionic surfactant outperforms non-ionic polyisobutylene succinimide for bind- ing to these aromatic species. The amine groups in the succinimide head-group only weakly adsorb on the polyaromatic deposit, while additional functional groups in the zwitterionic surfactant, particularly the ammonium ion, markedly enhance the binding strength. We decompose the adsorption free energies of the surfactants into entropic and enthalpic components, to find that the latter dominates the attraction from these non-aqueous solvents. The adsorption free energy of both surfactants is slightly weaker from n-hexadecane (diesel) than iso-octane (gasoline), which is due to the stronger molecular layering on the deposit of the former. Density functional theory calculations of the adsorption of DCA fragments validate the force field used in the molecular dy- namics simulations and provide further insights into the nature of the intermolecular interactions. The approach introduced here show considerable promise for accelerating the discovery of novel DCAs to facilitate more advanced fuel formulations to reduce emissions.
Identification of orthosteric inhibitors of MutSbeta ATPase function
Authors: Brace Gareth , Tillack Karsten , Johnson Peter , Ritzefeld Markus , Schaertl Sabine , Frush Elizabeth , Warfield Becka , Ballantyne George , Lee Jung-Hoon , Thieulin-Pardo Gabriel , Steinbacher Stefan , Thomsen Maren , Witte David , Finley Michael , Prasad Brinda , Monteagudo Edith , Plotnikov Nikolay , Pacifici Robert , Maillard Michel , Wilkinson Hilary , Iyer Ravi , Dominguez Celia , Vogt Thomas , Felsenfeld Dan , Haque Tasir
Published: October 2024

Orthosteric inhibitors of the human heterodimeric DNA mismatch repair complex MutSbeta were identified by high-throughput screening. Following extensive hit confirmation to remove false positives, two series were found to give consistent activity free of likely artefactual effects. Extensive hit profiling confirmed an ATP-competitive mode of action, and X-ray crystallography showed the inhibitors occupying the ATP-binding site of MSH3.
Photoemission Spectroscopy of Organic Molecules Using Plane-Wave/Pseudopoential Density Functional Theory: A Comprehensive Computational Protocol for Isolated Molecules, Molecular Aggregates and Periodic Systems
Authors: Porcelli Francesco , Colasante Emanuela , Filippone Francesco , Mattioli Giuseppe
Published: October 2024

The possibility to perform low-pressure gas-phase photoemission experiments has allowed the exploration at molecular scale of the complex correlation between electronic and structural properties of the matter. A significant advantage in the removal of the interference of the surrounding at low-pressure is also the easier correlation of the experimental results with theoretical ab-initio simulations. In the context of core ionization, the development of accurate methods for calculating inner-shell binding energies (BEs) offers a dual benefit. Firstly, it aids significantly in interpreting experimental data, helping to assign the contributions of all non-equivalent atoms, even in unresolved features arising from a molecular structure. Secondly, it allows for the anticipation of experimental results by accurately predicting spectral lines. In this context, we have developed and extensively tested a computational protocol based on plane- wave/pseudopotential density functional theory (PW-DFT) to predict X-ray photoemission spectra (XPS) in molecules and molecular aggregates. This protocol is based on a ∆SCF approach and has been tested comparing the present theoretical results with experimental XPS spectra collected from several molecular systems in gas phase, ranging from benzene derivates to biomolecules. Our calculations have been performed using semilocal and global/range-separated hybrid density functionals, containing increasing fractions of Hartree-Fock exact exchange (EXX). Specifically, PBE, B3LYP (20 % EXX), HSE (range separated with 25 % EXX at short range) and BH&HLYP (50 % EXX) have been used for the assessment of the computational protocol. Equation-of-motion coupled-cluster with single and double excitations (EOM-CCSD) has been employed as reference theoretical method for comparison. Regarding XPS, our PW-DFT approach demonstrated to be generally accurate and robust even using semilocal DFT, and to be also suitable for application to very large molecular systems and organic thin films deposited on inorganic surfaces. A proof of concept of a robust machine learning (ML) model for the prediction of C1s BEs in isolated organic molecules has been developed and it is discussed. We also present an early-stage verification of the efficiency of the density functionals introduced above for predicting valence-shell ionization spectra. Preliminary data suggest in this case of BH&HLYP as a promising alternative to EOM-CCSD.
Controlled Introduction of sp3 quantum defects in Fluorescent Carbon Nanotubes by Mechanochemistry
Authors: Sander Miriam , Metternich Justus , Dippner Pascal , Kruss Sebastian , Borchardt Lars
Published: October 2024

Precise control over low-dimensional materials holds an immense potential for their applications in sensing, imaging and information processing. The controlled introduction of sp3 quantum defects (color centers) can be used to tailor the optoelectronic properties of single-walled carbon nanotubes (SWCNTs) in the tissue transparency (> 800 nm) and the telecommunication window. However, an uncontrolled functionalization of SWCNTs with defects leads to a loss of the NIR fluorescence. Here, we use mechanochemistry with aryldiazonium salts to create quantum defects in SWCNTs. The reaction proceeds within 5 min without solvents or illumination and can be controlled by a varied mechanochemical energy impact. By working in the solid-state, this method presents an alternative synthetic route and marks a crucial step for tailoring photophysics of SWCNTs.
Probing the effect of the disordered flank regions on amyloid fibril growth and proliferation
Authors: Larsen Jacob Aunstrup , van Gils Juami , Ray Soumik , Dickmanns Marcel , Mohammad-Beigi Hossein , Zanganeh Masoumeh , Abeln Sanne , Buell Alexander Kai
Published: October 2024

Amyloid fibrils typically consist of a dense core made up of β-strands, with disordered flanks on either side, and sometimes interrupted by disordered loop regions (the fuzzy coat). α-synuclein found in Lewy Bodies of Parkinson’s Disease patients are mostly C-terminally truncated, meaning that a large fraction of the fuzzy coat of disease-related fibrils is enzymatically degraded in the amyloid state. We demonstrate that the proteolytic removal of the fuzzy coat leads to enhanced fibril-fibril interactions and flocculation, which renders the study of the role of the fuzzy coat in bulk solution very challenging. In order to overcome these challenges, here we use Quartz Crystal Microbalance with Dissipation (QCM-D), a surface based biosensing technique, to study the effects of proteolytic removal of the fuzzy coat of α-synuclein amyloids. We demonstrate that DissipationFrequency analysis can illuminate multiple simultaneous reactions and characterize the monomer-fibril interactions in detail. We find that removal of the fuzzy coat increases apparent fibril elongation rates permanently upon each proteinase treatment. Utilizing kinetic models, we demonstrate that our results cannot be rationalized by alterations of the elongation rate of fibrils alone, but indicates that removal of the fuzzy coat of α-synuclein fibrils enable secondary processes at neutral pH. We propose that the nature of the secondary processes investigated here may be highly relevant for understanding disease-related α-synuclein amyloid formation. Furthermore we suggest that the Quartz Crystal Microbalance with Dissipation is a particularly attractive platform for studying the effects of post-translational modifications on amyloid growth and molecular interactions.
C-H Bond Activation by Sulfated Zirconium Oxide is Mediated by a Sulfur-Centered Lewis Superacid
Authors: Lakliang Yutthana , Kolganov Alexander , Groves Marc , Sydora Orson , Pidko Evgeny , Conley Matthew
Published: October 2024

Sulfated zirconium oxide (SZO) catalyzes the hydrogenolysis of isotactic polypropylene (iPP, Mn = 13.3 kDa, Đ = 2.4, = 94 %) or high-density polyethylene (HDPE, Mn = 2.5 kDa, Đ = 3.6) to branched alkane products. We propose that this reactivity is driven by the pyrosulfate sites SZO, which open under mild reaction conditions to transiently form adsorbed SO3 and sulfate groups. This adsorbed SO3 is a very strong Lewis acid that binds 15N-pyridine or tri-ethylphosphineoxide (TEPO) (Eads > –39 kcal mol-1), reacts with Ph3CH to form Ph3C+, and mediates H/D exchange in dihydroanthracene-d4. DFT studies show that pyrosulfate sites have a modest 26.1 kcal mol-1 barrier to form the adsorbed SO3 and sulfate in the presence of a tetramer of propylene. Hydride abstraction from the tertiary C–H in this model is exo-thermic and subsequent -scission forms cleaved products. Analysis of the energetics provided here brackets the hydride ion affinity (HIA) of the adsorbed SO3 between 226.2 to 237.9 kcal mol-1, among largest values reported for a Lewis acid. This study explains how SZO, a classic heterogeneous catalyst whose activity is often attributed to Brønsted acidity, can form carbocations by a redox neutral hydride abstraction reaction by very strong Lewis sites.
Scope for development of Ayurvedic industrial pharmacy through 'good manufacturing practices' found in classical texts
Authors: Seema M B Dr.
Published: October 2024

None
Clinical Evaluation of Khadira Saara in Asrgdara wsr. to Menorrhagia
Authors: Suma V. Mallya Dr. , D Krishnamoorthy Dr.
Published: October 2024

None
An appraisal on Ashtasamskaras
Authors: Sreeshma S Dr. , Ashok. D Satpute Dr.
Published: October 2024

None
Duchene Muscular Dystrophy an ayurvedic management Case Study
Authors: Belavadi Dr.S.N. , A.S. Prashanth Dr
Published: October 2024

None
Dry Eye Syndrome An Ayurvedic Approach
Authors: Narayan Bavalatti Dr , Sapna D. B Dr , Shivanand Ghavimat Dr.
Published: October 2024

The optical stability and normal function of the eye depend on an adequate supply of fluid covering its surface. The tear films components interact to form a stable structure composed of mucin aqueous solution and lipid that protects the ocular surface and provides a medium for delivery of supportive and protective proteins. Alteration of any one of the tear film components can destabilize the tear film and lead to the initiation of inflammatory process of ocular surface which in turn may leads to dry eye syndrome. In ayurveda the disease Shushkakashipaka is very similar to Dry eye syndrome in modem ophthalmology. All acharyas included Shushkakshipaka as a disease which is affecting all parts of eye ball because this condition can cause major problems to all parts of eye like Shukla Krishna. Drishti mandalas if not treated property The different acharyas opinions that vitiation of Vata. Pittha and Raktha Will play the major role in the disease pathology Narrowing of palpebral aperature Crusting of lids. Blurred vision Stuck eyelids.foreign body sensation Pnckling pain teanng pain mucoid discharge etc are the clinical features explained in ayurveda. Systemic and local Vata-Pittha shamana and Dhatuposhana treatment is highly recommended starting from the Snehapana.
Phyto- Chemical Analysis of Saptavartita Guduchi Taila
Authors: Karishma Dr.
Published: October 2024

Ayurvedic Pharmaceutics is known as Bhaishajya kalpna. It has a wide range of medical preparations. Avartana is one among them. It is a process employed for preparing fortified medicated oils or ghee. An effort should be made to analyze the physical and chemical properties of Avartita tails at different stages which would ultimately alter the theraputic efficacy of the taila.
Clinical Study of Chandraprabhavati In Benign Prostatic Hyperplasi
Authors: Muralidhara Sharma Dr. , Prashanth K Dr.
Published: October 2024

ObjectivenbspTo evaluate the efficacy of Chandraprbha vati in symptomatic BPH casesMaterial and Methods-nbsp480 patients suffering from BPH were screened and 50 patients who fit into the criteria were taken for the study they were analyzed with AUA score each of the patient was gievn chandraprabha vati 400mg 1 tid for 12 wks. Clinical features were assessed after 12 wks and follow up done after 6 months.Results-nbspOut of 50 patients 13 cured of symptoms 16 significatn reduction in symptoms 7 reffered for intervention in 1 symptoms worsened 8 lost for follow up.Conclusion-nbspChandraprabhavati helps in satisfactory resolution of symptoms in prostatic hypertrophy patients with lower AUA Scores and lesser residual volumes.
A comparative clinical Evaluation of Trayodashanga Guggulu and Muustadiyapana Yoga Basti in Gridharsi
Authors: Hariprasad K Dr. , Dr. Sripathi Acharya Prof. , Guruprasad G Dr.
Published: October 2024

The most common disorer affects the movements of the leg in 30-60 years of mans life in Gridharsi Sciatica Syndrome. Lumbar disc lesions are responsible for the disorder and observed about 25 loss of work affects social and economic position of the individual and Family. As rational curative medicines are not known repeated uses of analgesics for prolonged time associcated with more serious and irreversible reactions. Now the whole scientific world has high hopes in ayurveds due to its safe and effective management. One of such efforts conducted in the OPD and IPD of MIAMS Manipal with 3 trial groups A- Trayodashanga guggulu B- Mustadiyapana yogabasti and C-Combined Trayodashanga guggulu and Mustadiyapana yoga basti for the period of 10 weeks in 30 diagnosed gridhrasi patients irrespective of their sex and age group 18-60.Study concluded all the 3 groups are effective treatment in gridhrasi and combined therapy Trayodashanga guggulu and Mustadiyapana yoga basti was more effective and showed highly significant result
Genetic Disorders and its Prevention- An Ayurvedic Perspective
Authors: Devi M Girija , Shivprasad Chiplunkar
Published: October 2024

Genetics is one of the most interesting topics of research in the current medical science. This science of heredity has got an elaborate description in the authoritative books of Ayurveda. Modern genetics deals with the combination of maternal and paternal genes as the responsible factor for an offspring. Genetics explains how the gametes get mixed with each other and how a specific gene gets stimulated. But books in Ayurveda deals much more than this. Ayurveda has explained the role of different factors favoring this development such as - Matruja Pitruja Atmaja Satvaja Rasaja Satymaja which explains that the child born to a couple is not merely a blend of parental and maternal characters alone but a amalgamation of many more factors. Ayurveda is conceptually well equipped to explain that the constitutional make up of a progeny can be decided by scientific methods in line with the present day Genetic Engineering concepts. Proper following of Rtukalaniyamas -Dos and donts at the time of Rtukala. avoiding Garbhopaghatakarabhavas -Factors hindering the growth of fetus. following of MasanumasikaParicharya -Month wise regimens for the pregnant women are few of them. Ayurveda advises pre-conceptional Shodhana upachara and proper diet for parents to protect the progeny from congenital disorders. The above said ideas can be implemented in fields like infertility management. preventing habitual abortions and certain hereditary diseases.Current study is a conceptual work regarding the effect of Aharavihara -Lifestyle of mother before and after conception in terms of Beejadosha and modifications in the current day life style to give birth to a healthy offspnng.nbsp
Evaluation of Guduchi Yoga In the Management of Vatarakta (Gouty Arthritis)- A Clinical Study
Authors: Shivprasad Huded Dr. , Sonia V. Gummadi Dr. , Ashwini HS Dr. , Kuber Sankh Dr.
Published: October 2024

The joint diseases are becoming the main health problem in the present era. Vatarakta is one of the main articular diseases which is characterized by severe pain tenderness inflammation and burning sensation in the affected joints. It is a tridoshaja vyadhi with vata pradhanyata and rakta as main dushya. Small joints of feet and hands are mainly affected in Vatarakta. Sedentary lifestyle is one of the etiological factors of Vatarakta. The etiology and Symptomatology of Gout is very much simiar to that of Vatarakta. Gout can be defined as the pathological reaction of joint or periarticular tissues which results from deposition of Monosodium urate monohydrate crystals in joints and tissues. Hyperurecemia can occur due to overproduction or under excretion of uric acid. In Ayurvedic dassics although we find plenty of dravyas for joint disorders the area ofnbsp joint diseases management still remains to be elusive. Therefore there is a definite need to explore more efficacious and radical cure to this chronic progressive illness. Guduchi Ttnospora cordifolia Willd is one such drug which is the drug of choice in the treatment of Vatarakta and according to the recent research claims cucumber juice extract Cucumis sativus Linn is proven to be effective in the management of Gout. Hence the present clinical study aims to evaluate the efficacy of combined effect of Guduchi extract and cucumber juice extract in the management of Vatarakta Gouty arthritis.ObjectivesToevaluate the therapeutic effect of Guduchi Yoga in bringing about remission of the symptomsillness in the patients suffering from Vatarakta Gouty arthritisTo evaluate the efficacy of Guduchi Yoga in hyperurecemia.Materials and Methods lt is a randomized single blind study with pre-test and post-test design. In this study 20 patients diagnosed as Vatarakta and met the American College of Rheumatology ACR criteria for acute Gouty arthritis were subjected to the clinical study. Detailed profile which incorporated relevant data like symptomatology physical signs and investigation reports were considered for assessment criteria. The Guduchi Yoga Aqueous extract of Guduchi and Trapusha was administered to patients of either sex in the dosage of 1gm BID with luke warm water after food for 12 weeks3 months.Observation and Results ln the present dinical study it was observed that Guduchi Yoga proved to possess statistically significant results in bringing out remission of the symptoms of patients suffering from Vatarakta Gouty arthritis followed by feeling of general wellbeing. It was also observed that the test drug helped in attaining normal serum uric acid levels after the treatment for 12 weeks.Conclusion From the present study it can be concluded that the combined effect of Guduchi and Trapusha extracts showed promising results with the above said criteria ofassessment without any untoward effects.
A Comparative Pharmacological Study on the Effect of Tagara [Valerina wallichii] and Jatamansi [Nardostachys jatamansi] In the Management of Anidra W.S.R. to Primary Insomnia
Authors: E Toolika , Mundugaru Ravi , . Sudhakara , B Ravishankar , Prakash B Narayana , Kumar Shetty Suhas , HP Savitha
Published: October 2024

The present study was undertaken to evaluate Tagara and Jatamansi for Certain CNS ativities to ascertain the basis for their use as sedative and hypnotics. The drugs were evaluated for hypnotic and sedative anti anxiety anti depressant and anti psychotic activities using standard experimental protocol. The data generated suggests that the test drugs Tagara and Jatamansi have complex CNS activity profile which is not easy to actegorize undr general CNS activity profile. Both possess significant anti-anxiety without significant sedative-hypnotic activity. This increases their utility for the patients suffering from anxiety due to sleep disturbances.nbsp
The Practice Model and Effectiveness Evaluation of Digital Transformation in Folk Art Education in Guangzhou Universities
Authors: Shengchuan Ruiji
Published: October 2024

This article briefly expounds on the connotation of digital transformation in folk art education in universities, as well as the application value of Guangzhou folk art in ideological and political education in universities. Subsequently, it elaborates on the practical models and effectiveness evaluation strategies of digital transformation in folk art education in Guangzhou universities, aiming to enrich research outcomes in this field and enhance the quality of folk art education.
Influence of Trust on Knowledge Sharing, Empirical Evidence and Managerial Implications
Authors: Memon Muhammad Abdul Basit , Jonejo Mansoor Ahmed
Published: October 2024

Purpose: This paper is an endeavor to present an account of the influence of trust on knowledge sharing to familiarize managers and practitioners with this essential aspect of knowledge sharing in light of existing literature and empirical evidence.                 
Design/Methodology/Approach: This research is based on the PhD research dissertation of the author and it was conducted through qualitative content analysis of research articles on the subject matter.
Findings: In the light of existing literature and available empirical findings, trust has been identified as not only an important, but the most important of the critical factors in sharing knowledge amongst organizational members, since trust reduces the feelings of strangeness and apprehension and enhances confidence of the organizational members to share the knowledge.
Implications/Originality/Value: This paper presents some key implications and recommendations for managers and practitioners to realize the significance of trust for knowledge sharing and for creating an organizational working environment characterized by a high level of trust among the organizational members to enable the efficient and effective sharing of knowledge among organizational members.
KAJIAN SIMBOLIK MOTIF BATIK BANDRONG LISUNG CIKADU KABUPATEN PANDEGLANG BANTEN
Authors: Fadillah Aufa , Yana Deni , Supriatna Supriatna
Published: October 2024

Batik is one of the fabrics that is closely related to the cultural values of a society and stores meaning in it through symbols and ornaments. For this reason, researchers examine the symbolic meaning of the Bandrong Lisung motif, Cikadu, Pandeglang Regency, Banten. This study uses a qualitative research method with a symbol theory approach from Susanne K Langer, namely discursive symbols and presentational symbols. A discursive symbol is a symbol that can be broken down into several elements in the motif for later analysis of its meaning. Meanwhile, presentational symbols provide an overall interpretation of a work. The results of this study indicate that every ornament contained in the Bandrong Lisung batik motif has a symbolic meaning. The ornaments are: women playing Bandrong Lisung art, lisung and pestle, plants/flowers, rhinoceros, curved edge decoration patterns, and triangle patterns. The meaning of the whole ornament is don't be afraid to walk in a strange place, if we continue to be brave, together and have strong determination it will produce beautiful things. Bandrong Lisung batik motif also has a message that no matter how tough a human's life is, he will return to his God.

Keywords: Batik, Bandrong Lisung, Cikadu, Symbolic

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Batik menjadi salah satu kain yang erat kaitannya dengan nilai budaya dari suatu masyarakat dan menyimpan makna di dalamnya melalui simbol dan ornamen. Untuk itu peneliti mengkaji mengenai makna simbolik pada motif Bandrong Lisung, Cikadu Kabupaten Pandeglang Banten. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan teori simbol dari Susanne K Langer, yaitu simbol diskursif dan simbol presentasional. Simbol diskursif merupakan simbol yang dapat dipecah menjadi beberapa elemen pada motif tersebut untuk kemudian ditelaah maknanya. Sedangkan simbol presentasional memberikan penafsiran secara keseluruhan pada suatu karya. Hasil penelitian ini menunjukkan bahwa setiap ornamen yang terdapat dalam motif batik Bandrong Lisung memiliki makna simbolik. Ornamen-ornamen tersebut ialah: ibu-ibu memainkan kesenian Bandrong Lisung, lisung dan alu, tumbuhan/ bunga, hewan badak, garis pola hiasan tepi berliuk-liuk, dan pola segitiga. Makna dari keseluruhan ornamen tersebut adalah jangan takut untuk berjalan di tempat yang asing, jika kita terus berani, bersama-sama dan memiliki tekad kuat maka akan menghasilkan hal yang indah. Motif batik Bandrong Lisung juga memiliki pesan bahwa setangguh apapun kehidupan manusia, ia akan kembali kepada Tuhannya.

Kata Kunci: Batik, Bandrong Lisung, Cikadu, Simbolik
PENGEMBANGAN MOTIF SINGOBARONG KERATON CIREBON BERGAYA FLATDESIGN UNTUK GENERASI MILENIAL
Authors: Djuniwarti Djuniwarti , Kurniawan Hadi , Karisa Silvy
Published: October 2024

West Java has many batik motifs that must to be preserved and introduced for the millennial generation. So far, the millennial generation has been considered more interested with Western fashion but many of them are also starting to be interested toward batik fashion actually. This research aims to develop alternatives design of the Singabarong batik motif into flat design style for the millennial target market. This research method uses a qualitative approach and design creation through three stages that are exploration, design and embodiment. This research resulted three developments of the Singabarong batik motif in flat design style that are the Singabarong Raja motif, the Singabarong Resi motif and the Singabarong Rama motif. The results of this study are expected to add insight and increase the interest of public especially millennials about the Singabarong batik motif preservation.

Keywords: Singabarong motif, flat design, millenial generation.

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Jawa Barat memiliki banyak motif batik yang perlu dilestarikan dan diperkenalkan kepada generasi milenial. Selama ini, generasi milenial dianggap lebih tertarik pada fesyen Barat, nyatanya banyak juga yang mulai tertarik pada fesyen berbahan batik. Penelitian ini bertujuan untuk mengembangkan desain alternatif motif batik Singabarong bergaya flat design untuk target pasar kaum milenial. Metode penelitian ini menggunakan pendekatan kualitatif serta penciptaan desain melalui tahap eksplorasi, perancangan dan perwujudan. Penelitian ini menghasilkan tiga pengembangan desain motif batik singabarong bergaya flat design yaitu motif singabarong Raja, motif singabarong Resi dan motif singabarong Rama. Hasil penelitian ini diharapkan menambah wawasan dan meningkatkan minat masyarakat khususnya kaum milenial terhadap kelestarian batik keraton motif Singabarong.

Kata Kunci: motif Singabarong, flat design, generasi millenial.
ANALISIS PENYUSUNAN RENCANA ANGGARAN BIAYA PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT BERDASARKAN STANDAR BIAYA MASUKAN (SBM)
Authors: Setiawati Kartini , Sodikin Muhamad
Published: October 2024

This research aims to analyze the preparation of the budget plan for research and community service costs. It is hoped that there will be uniformity and order in the preparation of the budget plan for the costs of research and community service activities in accordance with the 2023 Input Cost Standards (SBM). The research method used is a qualitative method with a study approach. case. The data collection technique for this research is by interviews and studying research proposals and PKM for the past three years. The results of this research can be used as a reference for researchers and PKM implementers within ISBI Bandung in preparing budget plans based on standard input costs.

Keywords: Cost Budget Plan, Standard Input Costs (SBM), Research and Community Service (PKM)

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Penelitian ini bertujuan menganalisis Penyusunan Rencana Anggaran Biaya Penelitian dan Pengabdian Kepada Masyarakat diharapkan adanya keseragaman dan ketertiban dalam Penyusunan Rencana Anggaran Biaya kegiatan Penelitian dan Pengabdian Masyarakat yang sesuai dengan Standar Biaya Masukan (SBM) Tahun 2023. Metode penelitian yang digunakan adalah metode kualitatif dengan pendekatan study kasus. Teknik pengumpulan data penelitian ini dengan wawancara dan mempelajari proposal penelitian dan PKM tiga tahun kebelakang. Hasil dari penelitian ini bisa sebagai acuan bagi para Peneliti dan pelaksana PKM di lingkungan ISBI Bandung dalam Penyusunan Rencana Anggaran Biaya berdasarkan Standar Biaya Masukan.

Kata Kunci : Rencana Anggaran Biaya, Standar Biaya Masukan (SBM), Penelitian dan Pengabdian Kepada Masyarakat (PKM)
DUNIA SENI RUPA INDONESIA: KRITIK SENI PAMERAN LIKE/DISLIKE
Authors: Putri Malena Wati , Nagara Martien Roos
Published: October 2024

Art is one of the important aspects in various facets of human life, therefore art exhibitions serve as crucial platforms for artists to interact with art enthusiasts and convey their artistic messages. Art exhibitions play a significant role in the development of visual arts in Indonesia. In this study, the author will examine, elaborate, and critique a solo exhibition by Taat Joeda titled â€œLike/Dislikeâ€ held at the Bandung Center for Culture Gallery. This research method involves direct observation or visitation to the exhibition and an overall analysis using art critique methods and mechanisms. The findings of the study reveal that the â€œLike/Dislikeâ€ art exhibition presents a refreshing approach in its theme about the tangle of undergrowth and captivating painting techniques. In conclusion, this research highlights the overall depth of the â€œLike/Dislikeâ€ exhibition with its theme â€œThe Beauty Hidden Within the Thicket.â€

Keywords : Painting, Exhibition, art critique

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Seni adalah salah satu hal yang penting dalam berbagai sisi kehidupan manusia, karena itu pameran karya seni merupakan platform penting bagi para seniman untuk berinteraksi dengan penikmat seni dan menyampaikan pesan-pesan artistik mereka. Pameran seni berperan sangat penting dalam perkembangan dunia seni rupa di Indonesia. Dalam penelitian ini penulis akan menelaah, menguraikan dan mengulas sebuah pameran tunggal oleh Taat Joeda berjudul Like/Dislike yang diadakan di Galeri Pusat Kebudayaan Bandung. Metode Penelitian ini melibatkan observasi atau kunjungan langsung ke pameran tersebut dan analisis keseluruhan menggunakan metode dan mekanisme kritik seni. Hasil penelitian penulis mengungkapkan bahwa pameran seni Like/Dislike menghadirkan pendekatan yang segar dalam tema tentang semak belukar dan teknik lukisan yang menarik perhatian. Kesimpulannya, penelitian ini menyoroti keseluruhan/kedalaman pameran Like/Dislike yang bertemakan â€œKeindahan yang Tersimpan Dalam Semak Belukarâ€

Kata Kunci : Lukisan, Pameran, Kritik Seni
DAUR NAIK LIMBAH TEKSTIL UNTUK PRODUK FESYEN READY TO WEAR DELUXE DENGAN TEKNIK QUILTING
Authors: Fajar Elina Almara , Falah Asep Miftahul , Atik Saftiyaningsih Ken
Published: October 2024

This research aims to explore the potential of textile waste recycling in the manufacture of deluxe ready-to-wear fashion products by applying quilting techniques. Against the background of the textile industry that generates huge waste and significant environmental impact, this research tries to provide a sustainable solution by utilizing textile waste as the main material. The Design Thinking method is used in five stages, namely Empathize to understand user needs and problems faced, Define to determine the problems to be solved, Ideate to generate creative ideas, Prototype to create initial products, and Test to test products with potential users. It is hoped that the results of this research can contribute to the development of environmentally friendly and innovative fashion products.

Keywords: Textile Design, Sustainable, Marbling, Batik Tulis, Ready To Wear Deluxe

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Penelitian ini bertujuan untuk menggali potensi daur ulang limbah tekstil dalam pembuatan produk fesyen ready-to-wear deluxe dengan menerapkan teknik quilting. Dengan latar belakang industri tekstil yang menghasilkan limbah yang besar dan dampak lingkungan yang signifikan, penelitian ini mencoba memberikan solusi berkelanjutan dengan memanfaatkan limbah tekstil sebagai bahan utama. Metode Design Thinking digunakan dalam lima tahapan, yaitu Empathize untuk memahami kebutuhan pengguna dan masalah yang dihadapi, Define untuk menentukan permasalahan yang akan diselesaikan, Ideate untuk menghasilkan ide-ide kreatif, Prototype untuk menciptakan produk awal, dan Test untuk menguji produk dengan pengguna potensial. Diharapkan hasil penelitian ini dapat memberikan kontribusi pada pengembangan produk fesyen yang ramah lingkungan dan inovatif.

Kata Kunci: Perancangan Tekstil, Sustainable, Marbling, Batik Tulis, Ready To Wear Deluxe
Impact of Rivers on Seasonal Changes in Water Level
Authors: Gharib Ghafur Pshtiwan , Faraidun Abdulrahman Rozhan
Published: October 2024

This study was conducted regarding the impact of rivers on Darbandikhan Lake's seasonal water level change. The aim of this study is to illustrate the impact of rivers on the lake through seasonal water level change from its tributaries. To achieve the research objectives, descriptive and quantitative methods were used. The findings showed that the highest water level of the lake was 467.72 m (a.s.l.) in Spring and that its storage capacity and area were 1.2554 billion m3 and 46.26 km2, respectively. In contrast, the lowest water level of the lake was 458.62 m (a.s.l.) in Autumn, with storage capacity and area of 908.2 million m3 and 32.38 km2, respectively. The river's share of discharge into the lake varied annually. The Tanjaro River averaged 6 m3/s (19.6%), the Chaqan River 0.47 m3/s (1.52%), the Zalm River 1.17 m3/s (3.77%), the Sirwan River 20.55 m3/s (66.28%), and the Zmkan River 2.74 m3/s (8.83%), all of which contributed to the lake annually. River discharge was influenced by physical factors such as topography, slope, and climatic elements, in addition to human factors such as water resource management policies, population and land use/land cover in the study area.
Desenvolvimento do Guia OferTEC: uma estratégia para a validação da oferta de um curso técnico articulada às demandas do setor produtivo local
Authors: Marques Germann Cristiane , Gruber Crislaine , Wollinger Paulo Roberto
Published: October 2024

O artigo tem por objetivo apresentar o desenvolvimento do “Guia OferTEC: uma estratégia para a validação da oferta de um curso técnico articulada às demandas do setor produtivo local”. O produto educacional divide-se em primeira e segunda parte. Como resultado, metade dos participantes recomenda a oferta do Curso Técnico em Cozinha, uma vez que a região da Associação de Municípios do Extremo Sul Catarinense (AMESC) carece de profissionais para atuarem no segmento de alimentação. Por fim, espera-se que o Guia possa contribuir para aprimorar o planejamento da oferta de cursos da educação profissional e tecnológica (EPT).
Revisitando a metodologia das escolas comerciais de treinamento dos anos 1970 no Senac
Authors: Thies Rosemar , Allain Olivier
Published: October 2024

O presente estudo consiste em um resgate das empresas comerciais de treinamento (ECTs) do Senac, implementadas nos anos 1970, consideradas aqui como uma metodologia ativa que permite o engajamento de aprendizes em obras laborais de suma importância para o desenvolvimento profissional. Foi feito um levantamento bibliográfico e documental sobre as ECTs, seguida de entrevistas para coletar depoimentos de professores e coordenadores que atuaram nesse processo. Isso permitiu uma melhor compreensão dessa metodologia baseada em obras laborais, suas implicações didáticas e de aprendizagem, além de uma apreciação de seu papel por atores que tiveram contato efetivo com ela. Por fim, avaliamos os limites e o potencial de uma possível retomada das ECTs no ensino técnico em administração.
Materialização do ensino híbrido em um curso técnico em administração
Authors: Pasqualli Roberta , Dos Anjos Leandro de Souza Vanuza
Published: October 2024

O artigo tem como objetivo apresentar o olhar dos docentes de um curso técnico em administração integrado ao ensino médio quanto à materialização do ensino híbrido enquanto modelo de ensino. Trata-se de uma pesquisa qualitativa, com pesquisa bibliográfica e de campo. Os resultados apontam que, após a pandemia de covid-19, o ensino híbrido continuará a ter papel importante no curso investigado. O modelo de ensino traz benefícios e oportunidades, mas também desafios, como o acesso e a utilização de tecnologias, infraestrutura física e internet, e principalmente a formação dos professores.
Educação permanente como ferramenta para melhorar indicadores de infecção relacionados à assistência à saúde
Authors: Fagundes Fernandes Tainara , Grego Maia Ludmila
Published: October 2024

Com o objetivo avaliar a implantação de estratégias de educação permanente em saúde (EPS) para os indicadores de infecções hospitalares (IRAS) em hospital público, o estudo transversal foi realizado com equipe profissional de UTI, com intervenção educativa e análise de indicadores pré/pós-intervenção. A EPS com a equipe resultou na melhoria dos escores pós-intervenção. O potencial de uso de estratégias colaborativas para identificar intervenções e ações necessárias para monitorar e conter IRAS são imprescindíveis para uma assistência de qualidade pela equipe multiprofissional.
Utilização da internet no contexto socioeducacional por jovens alunos do ensino médio
Authors: Wanzeler de Souza Reliane , Miranda Veloso Silva Benilda
Published: October 2024

O objetivo do estudo foi investigar o uso da internet no contexto socioeducacional por jovens/alunos do 1º ano do Ensino Médio, da Escola Estadual Profª. Osvaldina Muniz, no Munícipio de Cametá, no Pará. Metodologicamente, o estudo constituiu uma pesquisa qualitativa com abordagem de estudo de caso, com questionário semiestruturado como instrumento para coleta de dados e apreciação dos dados por análise de conteúdo e interpretação do objeto por triangulação dos dados. O referencial teórico da pesquisa está sustentado nos seguintes teóricos: Levy (1999), Pinheiro (2007), Araujo; Alves (2013), Moran (1997) e Castells (1999), entre outros. Os resultados revelam que os alunos do Ensino Médio permanecem entre 15h e 20h por dia conectados às redes sociais, buscando informações, transitando em muitas abas, interagindo, entre uma navegação e outra, principalmente com perfis do Facebook e do Instagram. A pesquisa conclui que os jovens/alunos utilizam a internet para buscas incessantes por informação, entretenimento, relações virtuais, como forma de conhecer pessoas e por distração. Isso caracteriza que eles precisam de mediação pedagógica para estarem melhor conectados e terem resultados significativos no processo de formação integral como sujeito que precisa intervir ativamente na sociedade.
Safety and efficacy of a feed additive consisting of tartrazine for its use in baits for freshwater fish (GIFAP)
Authors:   EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa Roberto Edoardo , Azimonti Giovanna , Bonos Eleftherios , Christensen Henrik , Durjava Mojca , Dusemund Birgit , Gehring Ronette , Glandorf Boet , Kouba Maryline , López‐Alonso Marta , Marcon Francesca , Nebbia Carlo , Pechová Alena , Prieto‐Maradona Miguel , Röhe Ilen , Theodoridou Katerina , Aquilina Gabriele , Bastos Maria , Bories Georges , Brantom Paul , Gropp Jurgen , Svensson Kettil , Tosti Luca , Finizio Antonio , Dioni Anna , Dulak‐Lis Maria , Galobart Jaume , Holczknecht Orsolya , Manini Paola , Navarro‐Villa Alberto , Plaza Daniel Pagés , Pizzo Fabiola , Radovnikovic Anita , Vettori Maria Vittoria , Amaduzzi Angelica
Published: October 2024

Abstract
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of tartrazine as sensory additive (functional group: (a) colourants: (i) substances that add or restore colour in feedingstuffs). Tartrazine is intended to be incorporated in fishing baits up to a maximum of 30 mg/kg in complementary feed in order to colour them and attract fish in freshwater (ponds, rivers), for both recreational and competitive fishing. The additive is not intended for use in aquaculture. Tartrazine is already authorised for use with cats and dogs, ornamental fish, grain‐eating ornamental birds and small rodents. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the use of tartrazine in the preparation of baits for freshwater fish under the proposed conditions of use is of no concern for the target animals. The use of tartrazine as a feed additive under the proposed conditions of use is considered safe for the consumer and the environment. Regarding the user safety, the additive should be considered a dermal and respiratory sensitiser. Inhalation and dermal exposure are considered a risk. The FEEDAP Panel could not conclude on the irritation potential of the additive. In absence of data, no conclusion can be reached on the efficacy of tartrazine in freshwater fish baits.
Generating wildlife density data across Europe in the framework of the European Observatory of Wildlife (EOW)
Authors:   ENETWILD‐consortium, Guerrasio T , Carniato D , Acevedo P , Apollonio M , Arakelyan M , Arnon A , Beatham S , Belova O , Berde L , Berdión O , Blanco‐Aguiar JA , Bleier N , Burgui Oltra JM , Carvalho J , Casaer J , Dijkhuis L , Duniš L , Ertuk A , Dal Mas M , Ferroglio E , Forti A , Gačić D , Gavashelishvili A , Hillström L , Jenječić M , Ježek M , Keuling O , Licoppe A , Liefting Y , Martinez‐Carrasco C , Olano I , Palencia P , Plis K , Podgorski T , Pokorny B , Rowcliffe M , Santos J , Smith GC , Sola de la Torre J , Stoyanov S , Zanet S , Vicente J , Scandura M
Published: October 2024

Abstract
The European Observatory of Wildlife EOW, as part of the ENETWILD project, represents a collaborative network that has been operating since 2021 to develop and implement standardized protocols to obtain harmonized data on distribution and density of target mammal species. In so doing, the EOW aims at contributing to improving the quality of data that are available for wildlife management and risk assessment on a European scale. This report describes the activities carried out during the 2023 EOW campaign, which was joined by a total of 30 organizations who committed to collect data in 44 sites across 22 different countries. We present data on the distribution and density of three species – wild boar (Sus scrofa), European roe deer (Capreolus capreolus), and red fox (Vulpes vulpes) – obtained by implementing a camera trapping protocol and by fitting the random encounter model (REM) for density estimation. Camera‐trap images were processed using the Agouti platform and some of its tools specifically designed for the management of camera trapping projects. This includes the use of photogrammetry to obtain parameters for the REM directly from the sequences of images. A total of 24 EOW sites were monitored in past years as well, providing multiannual density estimates and population trends and highlighting an improvement in the precision of the estimates, related to the improved study design and protocol implementation. We also describe the activities of the 2024 campaign, carried out as part of ENETWILD 2.0, where big efforts were made to expand the network, focusing on sites at risk of African Swine Fever, with wild boar/pig interactions and containing wetlands, as potential hubs for Avian Influenza. This effort resulted in the engagement of 40 participants monitoring 64 study sites (27 countries), including 28 study sites located either in infected areas or < 100km from the ASF frontline, and 25 sites with wetland habitats. Furthermore, in at least 20 sites pig farming is practised either intensively, extensively or as backyard farming. Finally, synergies were established with other international initiatives related to wildlife monitoring and disease prevention, with the aim of sharing experiences and sustaining a transnational data collection and harmonization.
Development of a roadmap for action on the application of Omics and associated Bioinformatics Approaches in Risk Assessment
Authors: Radio Santiago , Di Marsico Marco , Bersani Costanza , Malinverni Roberto , Casacuberta Josep , Corpetti Chiara , Cigliano Riccardo Aiese , Sanseverino Walter
Published: October 2024

Abstract
The implementation of omics technologies and associated bioinformatics approaches hold significant promise for generating additional evidence for food and feed risk assessments thereby enhancing the European Food Safety Authority (EFSA) capacity to deliver scientific opinions and guidance documents in the future. To explore this possibility, EFSA launched a Call for the development of a roadmap to identify the main actions needed for a wider use of Omics in future risk assessments. To address this objective, this action roadmap outlines six project proposals. These proposals are based on a comprehensive mapping of the state‐of‐the‐art omics and associated bioinformatics technologies in research, EFSA's activities as well as current and planned activities from other relevant regulatory bodies and organisations. The outlined recommendations also address some of the identified main knowledge gaps and highlight the added value that further investments in the different food & feed safety scientific domains could bring. In addition, the work in this roadmap addresses some key challenges and blockers that might hinder a wider integration of omics in risk assessment and leverages on the opportunities for cooperation with external stakeholders. Finally, this roadmap provides suggestions on how EFSA may more broadly and effectively engage with relevant stakeholders in the use of omics technologies and associated bioinformatics approaches in regulatory science.