bluuebunny/crossref_metadata_2025 huggingface dataset:
Penilaian Risiko Pada PDAM Tirta Kencana dengan Metode Fuzzy Failure Mode and Effects Analysis
Authors: Suriyanto  , Anggriani Profita  , Wara Widyarini Endah Saptaningtyas
Published: March 2023

PDAM Tirta Kencana Kota Samarinda adalah BUMD di bidang jasa pelayanan air minum yang dalam menjalankan bisnisnya tidak terlepas dari adanya risiko. Oleh karena itu metode Fuzzy Failure Mode and Effects Analysis (Fuzzy FMEA) digunakan untuk mengidentifikasi, menganalisis, dan mengevaluasi risiko. Identifikasi risiko dikelompokkan berdasarkan divisi di bawah naungan Direktur Teknik. Dari hasil pengolahan data Fuzzy FMEA didapatkan sebanyak 14 risiko keseluruhan dari 5 divisi dan risiko prioritasnya adalah kurang atau berlebihnya air bersih yang diproduksi terhadap aktual kebutuhan pemakaian air bersih (554) high, risiko kualitas air baku yang akan diproduksi tiap-tiap IPA menjadi turun pada daerah tangkapan air (548) high, risiko aliran air distribusi pada jaringan pipa distribusi tidak bisa dikendalikan (538) high, risiko air baku pada daerah tangkapan air tidak bisa diolah (504) high, dan risiko aliran air pada jaringan pipa distribusi untuk pasokan air ke pelanggan terganggu atau mati (490) high. Untuk memitigasi risiko prioritas maka diusulkan 7 usulan mitigasi risiko.
Hernias umbilicales en la población pediátrica
Authors: Navas Gámez Daniela , Barrantes Solano María José , Núñez Segura Nicole
Published: March 2023

La hernia umbilical es la patología que ocurre con mayor frecuencia en niños y adultos mayores, donde aproximadamente hasta 10% de los infantes sufrirán de esta patología. Se estima que 8 de cada 10 días niños afectados podrá superar esta condición por mecanismos fisiológicos antes de los 3 años. Mientas que, en los adultos, cerca del 90% de los afectados se produce debido a debilidad en la pared abdominal, especialmente en el área que rodea el ombligo.
Se considera una afección benigna, que se puede someter a tratamiento quirúrgico, siendo considerada la cirugía realizada con mayor frecuencia; sin embargo, existe el riesgo de que los pacientes sufran de ciertas complicaciones, como dolor intenso en la zona umbilical, además de que esta área tomará un tono rojizo, que se podría desencadenar secundario a una oclusión intestinal aguda, la cual sin duda necesitará cirugía de emergencia.
Visión general sobre sangrado uterino anormal: evaluación clínica y manejo
Authors: Hernández Lee Allison , Quiroz Soto César David , Rosales Víquez Marvin
Published: March 2023

El sangrado uterino anormal (SUA) es un motivo frecuente en la consulta ginecológica debido a su alta incidencia, el cual afecta en la calidad de vida de muchas mujeres. En términos generales, el SUA es cualquier sangrado de origen ginecológico que presenta anormalidades en su frecuencia, intensidad o volumen; estos pueden repercutir en consecuencias a corto, mediano o largo plazo; entre ellas puede provocar anemia, interferir con las actividades diarias y generar preocupaciones sobre el cáncer de útero. Según su etiología, se puede subdividir en dos agrupaciones: estructurales y no estructurales (PALM-COEIN), esta clasificación proporciona la facilidad en la investigación epidemiológica, entender la etiología y brindar el manejo optimo, el cual debe de ser personalizado; este último se divide en tratamiento hormonal y no hormonal.
Síndrome de Budd-Chiari: abordaje y manejo
Authors: Cesare Pérez Sara , Murillo Barquero Fabian , Obaldía Mata Alejandrina Paola
Published: March 2023

El síndrome de Budd-Chiari se cataloga dentro de las enfermedades poco frecuentes, con una incidencia de 0.45 por cada millón de personas. Consiste en una obstrucción al flujo venoso hepático que obedece a múltiples etiologías, más comúnmente a una trombosis venosa, generando una congestión hepática con aumento de presión venosa portal, produciendo así fibrosis y eventualmente falla hepática. Su manejo se orienta en revertir la obstrucción, mejorado el flujo sanguíneo y la perfusión para preservar la función del órgano.
Cardiomiopatía arritmogénica de ventrículo derecho
Authors: López Tristán Silvana
Published: March 2023

Las cardiomiopatías arritmogénicas son enfermedades del músculo cardiaco con predisposición a arritmias no causadas por hipertensión, isquemia o enfermedad valvular. Dentro de este grupo se encuentra la miocardiopatía arritmogénica de ventrículo derecho, que ahora también se sabe que puede ser de ventrículo izquierdo. Esta es una enfermedad hereditaria usualmente autosómica dominante, y en la mayoría de los casos causada por una mutación en los desmosomas que participan en la unión celular; esto provoca que ante un estrés se produzca muerte de miocitos y reemplazo de estos por tejido fibrograso, predisponiendo a arritmias mortales y progresión a insuficiencia cardiaca, imitando a una miocardiopatía dilatada. El curso natural de la enfermedad clásico se caracteriza por cuatro fases: inicialmente, se presenta la fase oculta, manifestada exclusivamente por arritmias mortales y muerte súbita; posteriormente, se da la alteración eléctrica, en la cual hay alteraciones en el electrocardiograma y en las pruebas de imagen; seguido, por la falla de ventrículo derecho; finalmente, la falla biventricular. El diagnóstico se confirma utilizando los criterios diagnósticos propuestos por la “International Task Force” (ITF), idealmente con pruebas no invasivas, o en última instancia, con pruebas invasivas; posteriormente, se debe estratificar el riesgo para definir el tratamiento. Para todos los pacientes es esencial la restricción de la actividad física, y para la mayoría se utilizan beta bloqueadores. La decisión de colocar un DAI (desfibrilador automático implantable) y uso de otros antiarrítmicos o ablación se hace según las características de cada paciente. Para los pacientes con sospecha, pero sin confirmación diagnóstica, lo más importante es el seguimiento estrecho para un diagnóstico temprano.  El pronóstico varía con una mortalidad de 0.08% a 3.6% anual, debido a la heterogeneidad en la presentación de la enfermedad.
Cefalea por abuso de medicamentos
Authors: Fallas Santana Cilian , Quesada Salas Allan Humberto , Porras Vargas Albin Gerardo
Published: March 2023

La cefalea por abuso de medicación es una cefalea secundaria que se desarrolla dentro un comportamiento de consumo excesivo e inadecuado de medicación analgésica para tratar crisis de cefaleas primarias, como la migraña y la cefalea tensional. Esto provoca una gran morbilidad y cronificación de la cefalea de base con incremento de las crisis de dolor, que aumentan aún más el consumo de analgésicos, provocando un espiral de cada vez mayor consumo y frustración tanto para el paciente como para el clínico tratante. La supresión inicial y el control posterior de la medicación analgésica, la inclusión y adherencia de un tratamiento preventivo para la cefalea primaria, y la educación constante del paciente, constituyen los pilares de tratamiento.
Lumbalgia: principal consulta en los servicios de salud
Authors: Douglas Clayton Shaquille Anthony , Rodríguez Jarquín Dylana , Zumbado Víquez Silvia
Published: March 2023

La lumbalgia es un problema de salud pública que implica grandes consecuencias para el sistema de salud y para quienes sufren algún episodio de esta patología, ya que en ocasiones se torna incapacitante para quien lo sufre. Es importante conocer la clínica de las diversas presentaciones de la lumbalgia y reconocer los factores de riesgo o banderas rojas, para brindarle el mejor abordaje terapéutico. De este modo, se deben establecer estudios de imágenes para determinar con mayor claridad la sintomatología y buscar el mejor escenario para el paciente. Se debe tomar en cuenta que el reposo absoluto por más de 48 horas puede ser perjudicial en la lumbalgia, y que se debe incluir como parte fundamental en su tratamiento las actividades diarias que no requieran esfuerzo físico; asimismo, la primera línea de tratamiento es el paracetamol, debido a los mínimos efectos adversos que ocasiona, comparado con los antiinflamatorios no esteroideos. La combinación de analgésicos con complejos de vitamina B aumenta la eficacia del tratamiento y brindan un mayor alivio de la sintomatología. Los opioides de baja intensidad pueden ser de utilidad en los casos refractarios a AINES, y los esteroides son de beneficio en las lumbalgias con componentes inflamatorios.
Tumor neuroendocrino de origen primario desconocido
Authors: Gray Torres Shenely Vaneza
Published: March 2023

Los tumores neuroendocrinos son un grupo heterogéneo de tumores que se forman en células capaces de producir hormonas en la sangre, las cuales reaccionan como resultado de una señal del sistema nervioso. Dichos tumores pueden producir más hormonas de lo habitual, lo cual causa sintomatología diferente. Pueden desarrollarse en cualquier órgano del cuerpo, aunque es más frecuente su presentación en el tubo digestivo, páncreas y tracto bronquiopulmonar.
Aproximadamente, un 65% pertenecen al tubo digestivo, 25% al tracto bronquiopulmonar y un 10% es considerado como “otros”. Existe diversidad de características clínicas, lo cual se encuentra unido a una baja incidencia. Se estima en 6.98 casos nuevos por cada 100,000 habitantes, esto hace que sean difíciles de diagnosticar, ya que en muchos casos los síntomas son inespecíficos o encontrados de manera casual, pero en más de la mitad de los casos el diagnóstico es tardío, cuando ya la enfermedad se encuentra avanzada, por lo que es necesario un manejo interdisciplinario.
Se considera que aproximadamente más de 12,000 personas en los Estados Unidos reciben un diagnóstico de tumores neuroendocrinos cada año, 175,000 personas conviven con esta enfermedad. En España se diagnostican 3,220 casos nuevos al año y 17,000 pacientes resultan afectados.
Paciente pediátrico con poiquilodermia de inicio temprano
Authors: Fiallos Brito Edisson Javier , Toapanta Yugcha Iván Guillermo , Villacrés Gavilanes Silvia Carolina
Published: March 2023

Se presenta el caso de una paciente femenina de 9 años de edad, con antecedentes de prematuridad, y retazo del crecimiento, que cursa con cuadro clínico de poiquilodermia de inicio temprano con diferentes características clínicas que incluyen talla baja, pestañas o cejas escasas, con sospecha de síndrome de Bloom vs síndrome de Rothmund-Thomson, el cual se abordó mediante el estudio de los genes BLM y RECQL4.
Margarita Salas: un gran nombre para un contrato postdoctoral mejorable
Authors: Font-JuliÃ¡n Cristina I. , OrduÃ±a-Malea Enrique
Published: March 2023

Tras un aÃ±o desde la incorporaciÃ³n de investigadores Margarita Salas en universidades y centros de investigaciÃ³n gracias al plan para la recualificaciÃ³n del sistema universitario espaÃ±ol llevado a cabo por el Ministerio de Universidades, esta nota recopila los principales problemas y limitaciones que derivan de este contrato postdoctoral, y esboza algunas posibles soluciones para futuras convocatorias de caracterÃ­sticas similares.
Avaliação do impacto emocional após a perda de um pet
Authors: Quintanilha Ferreira Cabral Carolina , Batalha Knackfuss Fabiana
Published: March 2023

The aim of this study was to evaluate the emotional understanding of those responsible after the loss of a companion animal, since their life expectancy is lower than that of humans, being therefore one of the first disconsolations to be experienced and overcome. It was found that in 78% of the cases, grief and all forms of emotional repercussions, even though they are relevant, mainly the feeling being equivalent to the loss of a family member in 50% of the cases, loneliness with 11% and 9% guilt, did not prevent them from having it again in their lives, as 75% had a pet in their homes again, even though 27% did not feel their grief validated or supported. The benefits of having lived with them was a decisive factor, as 90% were happier to have them in their lives, which led to the desire to welcome them into their home again, as 72% said they brought more happiness to the home and 13% felt emotional support from their company and 5% for empathy. In addition, 95% are interested in their children being able to share contact with an animal during their youth. The obstacles of the 25% of cases that did not have an animal again were; the lack of psychological preparation to go through the mourning again, financial impossibility, restricted space, lack of time and trauma of the lived experience with 40, 16, 16, 12 and 16% respectively.
Avaliação da longevidade espermática em sêmen refrigerado de Búfalos (Bubalus bubalis) à 5 oC
Authors: Almeida Jaci de , Parzewski Neves Beatriz , Ferreira Brito Mayara , Alexandra Becerra Becerra Verônica , Alencar Auler Patrícia , Almeida Resende Osvaldo , Roger Jean Marie Henry Marc
Published: March 2023

The semen of 11 buffalo bulls, Murrah, aged from 5 to 6 years, were collected by artificial vagina and submitted physical and morphological analysis of the characteristics of the semen. The objective of the experiment was to test, in vitro, the efficacy of four different extensors (Control -TRIS with 10% LDL- and the same extender at concentrations of 0.5, 1 and 2% of soy lecithin) on the sperm longevity of buffaloes in the refrigeration process at 5 °C for 1, 24, 48, 72, 96 and 120 hours. After collection, each ejaculate was fractionated in 4 aliquots to obtain 50×106 SPTZ/mL, packed in 0.5 mL vats, refrigerated for 4 hours, obtaining a cooling curve of 0.25o C/min. The reeds were kept refrigerated at 5° C and sequentially evaluated, the contents reheated at 37° C/30 seconds prior to the evaluation of sperm motility (total and progressive) using the computerized system. Samples were taken for evaluation by the hypo-osmotic test (HOST) at times 1, 24, 48 and 72 hours. For the statistical analysis, the STATA 12.0 package was used, and the values obtained were submitted to the Friedman test (P < 0.05). Progressive spermatozoa and plasma membrane integrity were higher (P < 0.05) in the TRIS extender with 10% LDL plus 0.5% soybean lecithin (67.2% and 67.9%, respectively) in the refrigeration process for 48 hours. In conclusion, a comparative evaluation of the sperm parameters revealed that the TRIS extender with 10% LDL plus 0.5% soy lecithin can be effectively used in the preservation of refrigerated buffalo semen in AI and IATF for up to 48 hours.
Abscesso aural em Tigre D’água (Trachemys scripta scripta): Relato de caso
Authors: Andrade Fernanda Dickel de , Buchholz Amanda , Mendonça Raphael de Oliveira
Published: March 2023

Aural abscess frequently occurs in chelonians and is characterized by the accumulation of caseous debris in the middle ear region. The signs are an increase in volume in the middle ear that can be unilateral or bilateral, head asymmetry, secretion at the dorsolateral pharyngeal outlet and at some points in the Eustachian tube. The diagnosis is basically made through clinical signs and radiographic examination. The established treatment is clinical and surgical. This report describes the case of a 6-year-old Trachemys scripta scripta, with an increase in volume in the region of the right ear, and gradual decrease in appetite and activity. After 10 days of the full established therapeutic protocol, the animal responded to the treatment and was discharged. This case report aims to show the success of the clinical and surgical treatment of the aural abscess in a Trachemys scripta scripta.
Diagnóstico de Leishmaniose canina por exame direto: Relato de caso
Authors: Silva Milena Alves da
Published: March 2023

Leishmaniasis is a zoonosis caused by a protozoan of the kingdom Protista of the genus Leishmania, it is a public health problem with an unfavorable prognosis for infected animals. The city of Unaí - MG in northwest Minas Gerais, is considered an endemic area of the disease, with great casuistry animals and humans. A dog with a complaint of rectal prolapse was examined and, after clinical investigation, the presence of seborrhea, lesions on the tip of the ear, skin peeling, exaggerated nail growth, perilabial ulcer was noted, and direct examination of the ulcers was performed, which demonstrated the presence of amastigote forms of Leishmania sp. and the animal was euthanized.
Urolitíase em cão da raça Pug: Relato de caso
Authors: Tavares Thaynan Cardoso , Dadalt Teixeira Nárgila , Moreira de Oliveira Junior Ivam
Published: March 2023

The objective of this study was to present a case of urolithiasis in a nine-year and eleven-month-old Pug, weighing nine kilos, with a history of urolithiasis. Upon physical examination, the animal presented apathy and abdominal pain on palpation. Upon ultrasound examination, it was not possible to identify the presence of uroliths in the urinary tract. The animal underwent surgical treatment, with cystotomy being the most suitable for this type of case. A cystotomy is an incision in the urinary bladder to remove uroliths, which can be made up of various minerals and of varying sizes. In the postoperative period, a diet change was indicated to reduce the chances of recurrences, since an inadequate diet is one of the factors for the formation of uroliths when there is certain predisposition.
Estudo retrospectivo de tumor venéreo transmissível em cães na cidade de Dourados, Mato Grosso do Sul
Authors: Pedrozo Camila de Souza , Abreu Loraine Baldissarelli de , Silva Paula Eduarda Valderino , Menegatti Rayssa Ludmila Menegatti , Fernandes de Melo Cristiane Maria
Published: March 2023

The Transmissible Venereal Tumor (TVT) is a neoplasm contagious and sexually transmitted, also known as infectious sarcoma, venereal lymphosarcoma, and Sticker Tumor. The general objective of this article was to verify the occurrence of TVT cases in dogs in the city of Dourados, in the State of Mato Grosso do Sul, in relation to gender, age, areas affected and cytology. The results showed a higher prevalence in females 116 (67%) than males 57 (33%), adults and in relation to the location, presented a greater occurrence in the genital region, followed by other localities. In cytology, the presence of round cells with round nucleus, some in the periphery, containing loose chromatin and evident nucleolus. Thus, it is important to emphasize that prevention campaigns should be performed with the purpose of clarify to the owners the importance of not let loose animals on the streets, as they act as potential reservoir for TVT.
Complexo gengivite-estomatite-faringite linfoplasmocitária felina: Relato de caso
Authors: Belisario Marcos Beatriz , Preventi Correia Beatriz , Augusto de Souza Guimarães Fábio , Lee Manoela , Bombardi Duarte Pedro Henrique , Suellen Souza Sá Thaynara , Andrade de Barros Michele , Segalla Caragelasco Douglas , Elias Silva Biazzo Leandro , Pascoal Livia Pascoal
Published: March 2023

Feline gingivitis-stomatitis complex is a disease of high incidence among felines, characterized by an intense inflammatory response, which can be local or diffuse, presenting with severe ulcerative proliferations in the oral mucosa that can observed from the accumulation of bacterial plaque and dental calculus, progressing to severe periodontal disease. Affected cats mainly demonstrate from mild dysphagia to severe reluctance to feed due to severe pain and oral inflammation. Decreased food intake can be characterized by apathy and progressive weight loss. This disease can affect animals between the ages of three to fifteen years old, although it is usually seen in eight-year-old cats. Clinical and, mainly, surgical treatment show, in most cases, a great improvement in the recovery of these patients. With this, the present essay aims to report a clinical case of gingivitis-stomatitis complex in a four-year-old feline patient treated at the Veterinary Clinic of PUC-Campinas, as well as to discuss its pathogenesis and therapeutic options.
A aquaponia como um sistema de produção hortaliças e peixes
Authors: Campos Andressa Fernanda , Padilha Alan Schreiner , De Araujo Ricardo , Da Rosa Nadir Paula , Domingues Sergio , Lalis Diovana de Mello
Published: March 2023

Aiming to align the production of animal products of excellent biological value with vegetables, whether they are until the seedling stage or adult plant, aquaponics brings this interrelationship of the technique for use in large and, mainly, in small productions. Aquaponics unites aquaculture with hydroponics, using methods of reusing water and nutrients due to filtering systems, with a lower impact of production on the environment. The system's sustainability is related to the lower demand for water, which provides production conditions for small producers, in addition to enabling production with the use of simple and tipper materials.
Japanese Encephalitis outbreak in Assam, Northeastern India, January to August 2022
Authors: Bandodkar Punam , Umapathy Murali , Murugesan Ramya , Ralte Malsawmtluangi
Published: March 2023

An outbreak of Japanese encephalitis (JEV) was detected in Assam, Northeast India, on July 1st, 2022. The source of human infection is known to be zoonotic transmission from culicine mosquitoes through bites. A total of 434 cases of JEV were recorded between July 1 and September 23, 2022, in 17 separate districts within Assam, India. The precise demographics of these JEV cases remain unknown. The case fatality rate in Assam during this outbreak was 21.43% (93); however, underreporting may occur. JEV is vaccine-preventable, and a vaccine was introduced under the Universal Immunization Programme (UIP) in endemic states to cover children at risk, but not adults. Such serious outbreaks have occurred in the past, with an outbreak in 2006 causing 6061 cases and 1500 deaths. Reports from the current outbreak suggest the cause of the outbreak may be due to prolonged floods resulting in water stagnation in Assam. An unusual feature of the current outbreak is the relatively high CFR and significant neurological involvement. Some key questions include: what is the demographic distribution of JEV cases in Assam? What is the vaccine coverage in Assam? How protective is the JEV vaccine?
Paracetamol as Analgesia Following Spontaneous Vaginal Delivery: Reappraisal of Practice
Authors: Mukhtar Nur Farihan , Ahmad Nazli Amanina Syamim , Ahmad Muhammad Ashraf , Suboh Nor Afidah
Published: March 2023

Background: We aim to determine the prevalence of perineal pain following postpartum vaginal delivery, the requirement of paracetamol as analgesia, and its associated factors. Methods: The study was performed from December 14, 2020, until February 14, 2021, in a single tertiary centre in northwest Malaysia. The pain score was assessed immediately postpartum and every six hours for the next 48 hours, and the requirement for paracetamol as analgesia was documented. Maternal sociodemographic data and baseline clinical details associated with the requirement for paracetamol were analysed. Results: A total of 285 study participants were included. The majority (93.0%) were Malays, with a mean age of 31.0 6.08 years. Majority of the women delivered their second child (36.1%) with a first-degree tear (46.7%). The majority neither required any analgesia within the first few hours of delivery in the labour room (71.3%) nor in the next 48 hours of ward observation (54.4%). The mean pain score following spontaneous vaginal delivery in the labour room was 4.0 1.07, while the mean pain score in the ward was 2.8 ± 1.05 (p<0.001). Logistic regression analysis determined that maternal weight (cOR: 1.02, 95% CI: 1.01, 1.04) and episiotomy (cOR: 3.28, 95% CI: 1.52, 7.08) were significantly predictive of paracetamol requirement as analgesia. Conclusion: Most of our population did not require oral analgesia in the postpartum period. However, the identification of susceptible individuals may guide clinicians to have a targeted approach for early management to ensure a positive birthing experience for all mothers.
Correlation between Profile and Outcomes of COVID-19 Patients
Authors: Bulat-ag Johnry C. , V. Portuguez Marc Ryan , L. Divina John Carlo
Published: March 2023

There is a need to perform investigations on the threats of COVID-19 and its correlation with patient outcomes to design a basis for a more responsive vaccine deployment approach. The present study assessed the outcomes of COVID-19 and its relationship with patients’ demographic and clinical profiles. A descriptive correlational design was utilized in this investigation. Results revealed a significant relationship between patients’ severity of symptoms and underlying conditions and outcomes. Patients with prior conditions such as Hypertension, Diabetes Mellitus and Chronic Obstructive Pulmonary Disease, and those manifesting shortness of breath were associated with a worse clinical outcome. This variable becomes a determinant of the severity of the disease and its outcomes. The implication of the study is that it provides knowledge of the disease and the classification of risks that impact the outcomes of COVID-19 patients.
The Relationship between Self-Awareness and Dietary Compliance in Patients with Type 2 Diabetes Mellitus
Authors: Yuswatiningsih Endang , Ningsih Arum Dwi
Published: March 2023

Background: The aim of this study was to investigate the correlation between self-awareness and dietary compliance in patients with type 2 diabetes mellitus. Methods: This study was correlational with a cross-sectional approach. The population was 253 respondents, all type 2 DM patients in the Jelakombo Jombang Health Center working area. The total sample had 147 respondents. The sampling technique used is simple random sampling. The independent variable is self-awareness, and the dependent variable is dietary compliance in type 2 DM patients. The data collection technique was a questionnaire, followed by data processing. The process involved editing, coding, scoring, tabulating, and analysing the data using the Spearman correlation test with an error rate of 0.05. Results: The data revealed that most of the respondents' self-awareness was good for 101 people (69%) and most of the respondents were obedient to their diets for 96 people (65%). The results of the analysis using the Spearman Correlation test, the probability value of 0.006 is smaller than the alpha value of 0.05, so H1 is accepted. Conclusion: The conclusion in this study is that there is a correlation between self-awareness and dietary compliance with type 2 diabetes mellitus patients. It is expected that type 2 diabetes mellitus patients will become more self-aware in terms of meeting their dietary needs.
Feasibility of Offering MS Nursing Program at Visayas State University
Authors: Cavite France Allan , Calungsod Phoebe Lynn , De los Santos Janet Alexis
Published: March 2023

Background: All academic institutions strive to provide competent programs and produce highly qualified graduates who can eventually compete in the local and international arenas. A feasibility study examines the viability of a project to check its success rate and make sure that the program meets the needs of its stakeholders. Objective: The objective of the study is to assess the practicality of offering a master’s degree program for nurses in the region and to evaluate the potential of the proposed program to respond to the needs of those pursuing graduate studies. Methods: A quantitative research design that was supplemented by qualitative responses was employed. The data was gathered using a convenience sampling technique, and the primary focus was on registered nurses in the healthcare industry. Descriptive statistics were utilised in the data processing and analysis of the results. Results: The intention to open a graduate program is relevant to the needs of working professionals. The results revealed that VSU meets the demand for nurses across regions, and this will potentially help nurse researchers develop, carry out, and support educational initiatives for graduate schools. Conclusion: The study shows that a significant number of nurses are interested in enrolling in a graduate program and they express their determination to achieve this goal, which shows that VSU meets the need.
Development and Validation of a Revised VAS-Anxiety Measurement Tools for Preschool Hospitalized Children
Authors: Islaeli Islaeli , Said Faridah Mohd , Nambiar Nisha , Umar Nur Syazana
Published: March 2023

Background: The visual analogue scale (VAS) instrument is proven to be reliable in measuring anxiety. Experts argue, however, that measuring the aspect of psychosocial trauma in a different language has limitations, especially among hospitalised children under the age of six. As a result, the study sought to revise and validate a trustworthy, child-friendly VAS for use in Indonesia. Methods: A preliminary survey was conducted among 81 respondents that met the inclusion criteria. An expert committee reviewed and revised the VAS-Anxiety-Indonesia for sensitivity and content validity. Thus, the Centre of Indonesia Language was charged with forward and backward translation from English to Indonesian and vice versa. In this study, data were collected in two phases. The first was the preliminary data collection from 21 respondents for face and content validity. The second phase recruited 60 respondents with retests and confirmations of modified items and components of VAS-A-Indonesia. Statistical analysis used a Pearson correlation coefficient of 0.05. The second test performed the content validity index, item correlation analysis, internal consistency for reliability testing, and Exploratory Factor Analysis. Results: The instrument consists of 12 items. With three factors to measure anxiety, they accounted for 65.2% of the overall variance. The content validity index was 0.825 (Aiken's V), item correlations ranged from 0.354 to 0.686, and Cronbach's alpha was 0.837. Conclusion: The Indonesian version of the VAS-A was a valid and reliable instrument for assessing the anxiety of preschoolers admitted to hospitals.
Effect of Hypno-Pressure on Mean Arterial Pressure in Patients with Cardiovascular Disorders
Authors: Nugraha Dwi Antara , Pujiastuti Sri Endang , Widiyanto Budi , Anwar Choiroel
Published: March 2023

Background: The mean arterial pressure (MAP) is the average arterial pressure during one cardiac cycle (systole, and diastole). MAP is affected by cardiac output and systemic vascular resistance, each of which is affected by several factors. Objective: This aim of this study is to determine the effectiveness of hypno-pressure on Mean Arterial Pressure (MAP) in patients with cardiovascular disorders. Methods: A quasi-experimental research design with a pretest-posttest with a control group was used in this study. Purposive sampling was used to select 56 respondents for this study, and twenty-eight respondents were randomly assigned to the experiment and control groups. The bedside monitor was used to measure MAP. Paired t-tests and Independent t-tests were used for data analysis. Results: There was a significant effect of hypno-pressure on the decrease of MAP value in patients with cardiovascular disorder with p-value 0.000 (<0.05), t = 7.217, and effect size of 1.18. Conclusion: Hypno-pressure could reduce MAP in patients with cardiovascular disorders.
Factors Determining Coping Strategy in HIV/AIDS Survival
Authors: Andriati Riris , Sari Indah Fenita Purnama , Pratiwi Rita Dwi
Published: March 2023

Introduction: Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) are still global health problems. Although the incidence of HIV has decreased from 0.40 people per 1000 to 0.26 people per 1000 people who are not infected in 2016, the trend is still concerning. Indonesia is ranked 5th as the country most at risk of HIV/AIDS in Asia, so the HIV/AIDS epidemic is also a problem in Indonesia. Objective: To identify determinants of coping strategies for HIV/AIDS survivors. Methods: This research is an analytic study with a cross sectional research design, and a quantitative approach. Research subjects in the group were selected randomly. The sample in this study, namely PLWHA who were recorded at the Regional General Hospital (RSUD) of Tangerang Regency, amounted to 36 PLWHA. Results: In Education with Coping Strategies, the p-value was 0.043. Conclusion: It can be concluded that there is a relationship between Education and Coping Strategies in Tangerang District Hospital, while the coping strategy with openness status, history of opportunistic infections and outcome expectations stated that there was no relationship with openness. status, history of opportunistic infections, and outcome expectations, with different p-values.
The Effect of the Innovative Healthcare Program "My Color Health" on Knowledge, Behavior, and Perception of Disease Severity in Patients with Diabetes and Hypertension
Authors: Muangthai Siriluk , Maneesuwan Thanaphon , Pinkumpee Pornthip , Wichienrat Phonphimon , Ditthaai Phattharaphon , Bunchean Thamonwan , Kantabanlang Yupawadee
Published: March 2023

Motivational program as a form of mutual aid could offer great benefits to promote healthy eating among Thai elderly with Diabetes and Hypertension. The purpose of this study is to examine the average, knowledge, practice recommendations, and patients' perceptions of the severity of their diseases before and after receiving the My Color Health Innovation. This quasi-experimental research used a one-group pretest-posttest design that aimed to examine the effects of the innovation "My color health" on knowledge, behavior, and the perception of disease severity in patients with diabetes and hypertension. This study used the concept of the 7-Color Ball. The sample consisted of 20 elderly people and was selected through purposive sampling. The research instruments consisted of the innovation "My color health" knowledge test behavior, and perception of the severity of diabetes and hypertension questionnaires. The questionnaire in Google Forms was used to collect data. The data were analyzed using descriptive statistics and paired t-tests. The results revealed that after using "My color health", the differences in the mean scores of knowledge, guidelines for practice, and perceived severity of diabetes and hypertension were statistically significant (P< 0.05). This research shows that the innovation of "My color health" can increase knowledge, behavior, and perception of the severity of diabetes and hypertension. It can be used as a guideline for the care of patients with uncontrolled diabetes and hypertension.
Analysis of Readiness to Become a Parent, Social Support and Marital Support with Parenting Self-Efficacy (PSE) among Mothers in Cibadung Village Gunung Sindur District Bogor Indonesia
Authors: Sansuwito Tukimin Bin , Said Faridah Mohd , Poddar Sandeep
Published: March 2023

Background: Based on the KPAI survey, 66.4% of fathers and 71% of mothers adopted parental care, and 47.1% of fathers and 40.6% of mothers communicated with their children for only one hour. This study aimed to determine the relationship between readiness to become a parent, social support, and marital support with parenting self-efficacy for mothers in RW 06 Cibadung Village, Gunung Sindur District. Methods: This quantitative method uses an analytical design with a cross-sectional approach. The purposive sampling technique was used in this study, with a total of 145 samples; data were analysed using the Spearman Rank correlation test. Results: The study showed that the statistical test of readiness to become parents with parenting self-efficacy had a p-value = 0.015. The statistical test of social support with parenting self-efficacy got a p-value = 0.043, and the statistical test results of spousal support with parenting self-efficacy got a p-value = 0.911. Conclusion: The study showed that there is a relationship between parenting readiness and parenting self-efficacy, no relationship between social support and parenting self-efficacy, and no relationship between marital support and parenting self-efficacy. This study suggests increasing readiness to become parents by changing the perception of parenting so as not to depend on social and marital support.
Determinant of Perception Factors in People Living with HIV/AIDS (Plwha) with the Attitude of Preventing Opportunistic Infections
Authors: Sari Indah Fenita Purnama , Eryando Tris
Published: March 2023

HIV and AIDS are worldwide health concerns. Opportunistic infections are brought on by a weakened immune system and the introduction of germs (bacteria, fungi, and viruses) into the body. Opportunistic Infections (OIs) can cause death in >90% of AIDS patients. The objective of this research is to identify perception factors associated with a positive attitude toward preventing opportunistic infections in people living with HIV/AIDS (PLWHA). This research was an analytical study applying a cross-sectional design and quantitative approaches. This study included 30 samples from PLWHA from the General Hospital of South Tangerang City, Indonesia. Samples were collected using a non-random sampling technique involving accidental sampling. From the results of the study, a relationship of perceived threat (p-value = 0.001; r = 0.515), perceived susceptibility (p-value = 0.044; r = 0.345), perceived severity (p-value = 0.361), perceived benefit (p-value = 0.643), perceived barrier (p-value = 0.094; r = 0.463), and perceived self-efficacy (p-value = 0,004; r = 0.463) was obtained with the prevention attitude of opportunistic infections. The perceived threat is a major factor influencing attitudes toward OI prevention.
Application of the Levine Theory and Health Belief Model in Anemia and Thrombocytopenia in Pregnancy: A Case Report
Authors: Pamungkas Eny Dewi , Setyowati Setyowati , Afiyanti Yati
Published: March 2023

Pregnant women with anemia and thrombocytopenia are exposed to health risks. Therefore, Levine's conservation theory approach combined with the Health Belief Model theory could be applied to assist pregnant women to optimize their adaptive responses and achieve maximum health. Levine's conservation theory focuses on maintaining an individual’s integrity and helping them to adapt to their conditions through the principle of conservation. For the Health Belief Model theory, the involvement and belief of pregnant women are the main aspects required to prevent and treat anemia and thrombocytopenia through their perceived susceptibility, seriousness, benefits, and barriers. Five cases of pregnant women with anemia and thrombocytopenia were provided nursing care that used Levine's conservation and Health Belief Model theory. Doing so resulted in the pregnant women adapting to their conditions and prevented any adverse impacts on their pregnancy.
PHYSICO CHEMISTRY PROPERTIES OF PARTICLE BOARD BASED ON COCO DUST AND LIQUID NATURAL RUBBER
Authors: Sutanto T.D. , I. Gustian  , Suharso  , Ngatijo
Published: March 2023

A particle board is a board made of lignocellulosic material and together with an adhesive and then pressed. In this research, a particle board is made by mixing coco dust with a number of liquid natural rubber percentages. Next particle board is molded then dried and pressed to get 2,5 cm thickness and further characterization is carried out which consists of MOR, MOE, pull out the screw, content of water, density, thickness development, FTIR, and SEM test. FTIR spectrum was recorded on wave number 4000–400 cm-1 whereas micrograph SEM was recorded at 5000 times magnification. The test results show that the best conditions for making particle boards are obtained when using 50% liquid natural rubber. Under these conditions, the quality of the particle board which includes MOR, MOE, the screw hold strength, water content, density, and thickness development is 381.41 g/mm2 , 198.40 g/mm2 ,24440 g/mm2 , 1.94%, 1.6047 g/cm3 , and 7.5% respectively
A COMPARATIVE EVALUATION OF THE ANTIOXIDANT ACTIVITY OF LOCAL PLANTS ORIGINATED FROM SUMENEP REGENCY, EAST JAVA, INDONESIA
Authors: Ismawati  , R. Yuniastri  , N. Huzaimah  , T. Estiasih  , E. Martati  , D. Tarmadi  , W. Fatriasari  , Arung E. T. , M. Ismayati
Published: March 2023

This is the first study on the antioxidant activity and chemical analysis with PyGCMS of leave extract (B. pilosa, H. corymbosa, and P. pellucida) originating from the Sumenep regency, Indonesia. The higher yield extracts were B-1 and P-1, about 19.33% and 20.27%. The result of the DPPH test revealed that B-1 was the highest antioxidant properties, with an IC50 value of about 6.43%. The antioxidant properties were affected by the high phenolic content of B-1 (112.20%) and the absence of hydrolyzed tannins. The H-1 has higher phenolic content than B-1 but is contrarily in antioxidant activity. The carbohydrates derivatives were easier extracted in aqua dest extract has decreased antioxidant activity at H-1. In addition, as reported by GCMS, PyGCMS also showed terpenoid compounds, tannins, and flavonoids. The interaction between compounds in plant extracts plays a more critical role in antioxidant activity than certain compounds. B-1 extract has the potential as an antioxidant additive in the food, cosmetic, or advanced materials industry
ENHANCEMENT OF ANTIMICROBIAL MICRO CELLULOSE OF BAGASSE BY MODIFICATION WITH SILVER NANOPARTICLES
Authors: E. Rohaeti  , Ariyanti N. A. , Budiasih K.S. , A. Afikah  , Ayu S.M. , Annisa A. S. N. , E. Nuraini
Published: March 2023

The preparation of microcellulose from sugarcane pulp enzymatically and its modification with silver nanoparticles had been conducted in this study. The objectives of this research were to prepare and characterize microfiber cellulose, and also its application as an antimicrobial material. Micro cellulose has been prepared by enzymatic methods and then continued with ultrasonication. The characterization of microfiber cellulose has been conducted by determining wavelengths with UV-Vis, functional groups with FTIR, surface image with SEM, and crystallinity with XRD. Synthesis of AgNPs had been conducted by bioreduction method using red betel leaf extracts via ultrasonication and stabilized by 0.05% starch solution. Characterization of silver nanoparticles had been conducted by determination of wavelength with UV-Vis and particle size with PSA. The antimicrobial tests of microcellulose have been determined by measuring of clear zones in Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans. The characterization of microcellulose showed that wavelengths of micro cellulose at 300 nm, has C-O glycosidic bonds, the C=O, and lignin/hemicellulose. However, C=C lignin aromatic rings begin to disappear. Microcellulose size was 1 μm and crystallinity was 79.05%. The wavelengths in silver nanoparticles were shown at 424 nm. The diameter of silver nanoparticles was 88.6 nm. Micro cellulose with nanoparticle modification was the best in microbial inhibition
SIMULTANEOUS REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC) ESTIMATION OF AZELASTINE HYDROCHLORIDE, FLUTICASONE PROPIONATE, AND PHENYL ETHYL ALCOHOL IN DYMISTA (MEDA) NASAL SPRAY
Authors: Gupta A. K. , Singour P. K. , Jain S. K.
Published: March 2023

This work reported a reverse phase-high performance liquid chromatography method for quantitative estimation of Azelastine Hydrochloride, Fluticasone Propionate, and Phenylethyl Alcohol in Nasal Spray formulation. The assay involved an isocratic elution of these components by using Intersil Octadecylsilane (C18) column (25 cm x 4.6 mm x 5 μm) using mobile phase composition of Buffer: Solvent Mixture (40:60 %v/v) and pH adjusted to 6.5 with dilute orthophosphoric acid. The flow rate was 1.4 mLmin-1 and the analytes are monitored at 254 nm. Separation was completed within 20 minutes. Calibration curves were linear with correlation coefficient more than 0.99 over a concentration range of 50%, 75%, 100%, 125%, and 150% for Azelastine Hydrochloride, Fluticasone Propionate and Phenylethyl Alcohol. The method was proven to be accurate between 50 to 150% with 98 to 102 % recovery of the actives from a spiked placebo. The method was shown to be precise yielding acceptable results for the system reproducibility and method repeatability. All the validation parameters were within the acceptance range according to International Conference on Harmonization norms. The developed method is simple and rapid which could be applied for routine estimation of the formulation.
A REVIEW OF THE DEVELOPMENT OF THE GEL CASTING METHOD FOR POROUS CERAMIC FABRICATION
Authors: Eka Putri Suriati , Ahmad Ahyar , Raya Indah , Triandi Tjahjanto Rachmat , Natsir Hasnah , Taba Paulina , Karim Harningsih
Published: March 2023

The objective of this paper is to present an overview of the development of gel casting methods on synthesis techniques and the characteristics of gel casting porous ceramics and its applications. The gel casting method is a colloidal ceramic synthesis method that requires a short period for the ceramic body to develop. This review provides the latest developments in the gel casting process of synthesizing porous ceramics. At the beginning of the gel casting method development, the acrylamide (AM) system was the most commonly utilized system. Over time, the use of the AM system began to be minimized because of its toxicity. Researchers began to develop natural polymers as pore templates and natural minerals as raw materials in the gel casting method. In addition to polymers and raw materials, the gel casting process also requires additives such as gelling agents and dispersants. At the end of this review, a mapping of how to select the additives in the gel casting process, for AM systems and non-AM systems for the fabrication of porous ceramics is presented. The characteristic of porous ceramics produced by AM and non-AM systems are almost similar. Porous ceramic applications have been used as bone tissue supports, energy storage, filters, and catalyst support. This review will be a reference for future research related to the process of fabrication of advanced porous ceramics using the environmentally friendly gel casting method.
COMPUTATIONAL STUDY OF Acetylcholine esterase INHIBITION BY AZAPHENOTHIAZINE ANALOGUES
Authors: K. Premavathi  , P. Valentina  , N. Ramalakshmi
Published: March 2023

The present research is focused on new findings of azaphenothiazine analogs which is the promising lead moiety as the phenothiazine ring modified with azine ring as the basic nucleus reported from the literature survey that it has a wide spread of biological activity. The fifteen compounds were subjected to a molecular docking investigation using autodock pyrex, and it was discovered that ligand 4 with an ethyl group replaced gave the receptor a strong binding affinity of -8.6. Ligand 6having methyl group (showed the lowest binding affinity of -7.8. ligand 10 which is a substituted chlorine group gave good binding affinity and Ligand 13 showed significant binding affinity of -7.4 and -7.3 for the 2CMF active site of Acetylcholine esterase enzyme compared to imipramine (standard). The ADME property of selected moiety which is most important for drug development and discovery was done using SWISS adme and obeyed Lipinski rule 5 which plays an important role to predict physiochemical properties.