bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of initial material of winter soft wheat in terms of adaptability in the forest-steppe conditions of Novosibirsk region
Authors: Musinov K. K. , Likhenko I. E. , Surnachev A. S.
Published: April 2022

One of the main ways to obtain consistently high yields in Siberian conditions is the use of adaptive varieties. Selection plays a key role in solving this problem. Success in breeding for resistance to biotic and abiotic stresses depends on the correct choice of initial parental forms for crossing. The purpose of the study is to evaluate varieties and promising breeding lines of soft winter wheat of various ecological and geographical origin in terms of productivity and adaptive potential. The results of the study of 68 varieties and breeding lines of winter soft wheat are presented. The studies were carried out on the experimental field of the Siberian Research Institute of Plant Growing and Breeding, a branch of the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences. The most favorable conditions for the formation of the winter wheat crop were formed in 2021 (Ij=125.1). The least favorable conditions developed in 2020 (Ij= -171.2). The most winter-hardy varieties were Scepter, Novosibirskaya 32, Pamyati Chekurova, Omskaya 6. The Volzhskaya variety showed high plasticity (bi=1.49), but was not stable over the years. The most stable varieties among highly productive samples were Novosibirskaya 32 (δd² = 13.75), Lutescens 261-3 (δd² = 16.86), Pamyati Chekurova (δd² = 13.95), Zhemchuzhina Povolzh’ya (δd² = 10.33), Volzhskaya 22 (δd² = 22.70). Genotypes combining high rates of plasticity and stability Lutescens 261-3 (bi=1.26; δd²= 16.86) and Volzhskaya 22 (bi=1.97; δd² = 22.70). Samples of Pamyati Chekurova, Scepter, Omskaya 6 and Chekh 16 stood out for a number of indicators: in terms of stress resistance Уmin - Уmax = -51.9 ÷ -282.5; in terms of genetic flexibility (Уmax+Уmin)/2 = 568.8÷651.8; by yield variability V = 4.6÷26.4%; according to homeostasis Hom = 8.13÷94.88; by breeding value Sc = 391.3÷521.5. These samples are of interest in the selection of winter soft wheat to improve adaptability
Ten-year safety of pluripotent stem cell transplantation in acute thoracic spinal cord injury
Authors: McKenna Stephen L. , Ehsanian Reza , Liu Charles Y. , Steinberg Gary K. , Jones Linda , Lebkowski Jane S. , Wirth Edward , Fessler Richard G.
Published: April 2022

OBJECTIVE

The purpose of this study was to evaluate the safety of oligodendrocyte progenitor cells (LCTOPC1) derived from human pluripotent stem cells administered between 7 and 14 days postinjury to patients with T3 to T11 neurologically complete spinal cord injury (SCI). The rationale for this first-in-human trial was based on evidence that administration of LCTOPC1 supports survival and potential repair of key cellular components and architecture at the SCI site.

METHODS

This study was a multisite, open-label, single-arm interventional clinical trial. Participants (n = 5) received a single intraparenchymal injection of 2 × 106 LCTOPC1 caudal to the epicenter of injury using a syringe positioning device. Immunosuppression with tacrolimus was administered for a total of 60 days. Participants were followed with annual in-person examinations and MRI for 5 years at the time of this report and will be followed with annual telephone questionnaires for 6 to 15 years postinjection. The primary endpoint was safety, as measured by the frequency and severity of adverse events related to the LCTOPC1 injection, the injection procedure, and/or the concomitant immunosuppression administered. The secondary endpoint was neurological function as measured by sensory scores and lower-extremity motor scores as measured by the International Standards for Neurological Classification of Spinal Cord Injury examinations.

RESULTS

No unanticipated serious adverse events related to LCTOPC1 have been reported with 98% follow-up of participants (49 of 50 annual visits) through the first 10 years of the clinical trial. There was no evidence of neurological decline, enlarging masses, further spinal cord damage, or syrinx formation. MRI results during the long-term follow-up period in patients administered LCTOPC1 cells showed that 80% of patients demonstrated T2 signal changes consistent with the formation of a tissue matrix at the injury site.

CONCLUSIONS

This study provides crucial first-in-human safety data supporting the pursuit of future human embryonic stem cell–derived therapies. While we cannot exclude the possibility of future adverse events, the experience in this trial provides evidence that this cell type can be well tolerated by patients, with an event-free period of up to 10 years. Based on the safety profile of LCTOPC1 obtained in this study, a cervical dose escalation trial was initiated (NCT02302157).
Evolution of the patient-first approach: a dual-trained, single-neurosurgeon experience with 2002 consecutive intracranial aneurysm treatments
Authors: Waqas Muhammad , Monteiro Andre , Cappuzzo Justin M. , Tutino Vincent M. , Levy Elad I.
Published: April 2022

OBJECTIVE

The paradigm for intracranial aneurysm (IA) treatment is shifting toward a hybrid approach involving open and endovascular techniques. The authors chronicled the evolution of IA treatment by retrospectively examining a large series of IA cases treated by a single dual-trained neurosurgeon, focusing on evolving technology relative to the choice of treatment options, perioperative morbidity, and mortality.

METHODS

The aneurysm database at the authors’ institution was searched to identify consecutive patients treated with endovascular or open microsurgical approaches by one neurosurgeon during an 18-year time span. Patients were included regardless of IA rupture status, location or morphology, or treatment modality. Data collected were baseline clinical characteristics, aneurysm size, treatment modality, operative complications, in-hospital mortality, and retreatment rate.

RESULTS

A total of 1858 patients with 2002 IA treatments were included in the study. Three-hundred fifty IAs (17.5%) were ruptured. Open microsurgery was performed in 504 aneurysms (25.2%) and endovascular surgery in 1498 (74.8%). Endovascular IA treatments trended toward a growing use of flow diversion during the last 11 years. In-hospital mortality was 1.7% overall, including 7.0% in ruptured and 0.5% in unruptured cases. The overall complication rate was 3.3%, including 3.4% for microsurgical cases and 3.3% for endovascular cases. The rate of retreatment was 3.6% after clipping and 10.7% for endovascular treatment.

CONCLUSIONS

This study demonstrates complementary use of open and endovascular approaches for IA treatment. By customizing treatment to the patient, comparable rates of procedural complications, mortality, and retreatment were achieved for both endovascular and microsurgical approaches.
Correction of trigonocephaly after endoscopic strip craniectomy with postoperative helmet orthosis therapy: a 3D stereophotogrammetric study
Authors: Elawadly Ahmed , Smith Luke , Borghi Alessandro , Abdelaziz Khaled I. , Silva Adikarige Haritha Dulanka , Dunaway David J. , Jeelani Noor ul Owase , Ong Juling , James Greg
Published: April 2022

OBJECTIVE

Endoscopic strip craniectomy with postoperative helmet orthosis therapy (ESCH) has emerged as a less invasive alternative to fronto-orbital remodeling for correction of trigonocephaly. However, there is no standardized objective method for monitoring morphological changes following ESCH. Such a method should be reproducible and avoid the use of ionizing radiation and general anesthesia for diagnostic imaging. The authors analyzed a number of metrics measured using 3D stereophotogrammetry (3DSPG) following ESCH, an imaging alternative that is free of ionizing radiation and can be performed on awake children.

METHODS

3DSPG images obtained at two time points (perisurgical and 1-year follow-up [FU]) of children with metopic synostosis who had undergone ESCH were analyzed and compared to 3DSPG images of age-matched control children without craniofacial anomalies. In total, 9 parameters were measured, the frontal angle and anteroposterior volume in addition to 7 novel parameters: anteroposterior area ratio, anteroposterior width ratios 1 and 2, and right and left anteroposterior diagonal ratios 30 and 60.

RESULTS

Six eligible patients were identified in the operated group, and 15 children were in the control group. All 9 parameters differed significantly between perisurgical and age-matched controls, as well as from perisurgical to FU scans. Comparison of FU scans of metopic synostosis patients who underwent surgery to scans of age-matched controls without metopic synostosis revealed that all parameters were statistically identical, with the exception of the right anteroposterior diagonal ratio 30, which was not fully corrected in the treated patients. The left anterior part of the head showed the most change in surface area maps.

CONCLUSIONS

In this pilot study, ESCH showed satisfactory results at 1 year, with improvements in all measured parameters compared to perisurgical results and normalization of 8 of 9 parameters compared to an age-matched control group. The results indicate that these parameters may be useful for craniofacial units for monitoring changes in head shape after ESCH for trigonocephaly and that 3DSPG, which avoids the use of anesthesia and ionizing radiation, is a satisfactory monitoring method.
Дидактичні ігри на уроках музики
Authors: Пермяков О. А. , Власенко І. М. , Лаврентьєва О. О.
Published: April 2022

Мета пропонованого посібника - допомогти вчителям музики, що працюють у початкових класах, в організації й проведенні дидактичних ігор на уроках музики. У посібнику представлений теоретичний матеріал про основи гри; методика проведення дидактичних ігор на уроках музики в початкових класах; досвід роботи вчителів музики, описаний у методичній літературі: ігри на розвиток темпу й метроритму, звуковисотного чуття, чуття тембру, динамічного чуття, музичного сприйняття, музичної пам'яті, вокально-хорових навичок та інших музичних здібностей, а також різноманітні ігри, які можна використати на різних етапах уроку.
Організація самостійної навчальної діяльності студентів технолого-педагогічних спеціальностей засобами інформаційно-комунікаційних технологій
Authors: Цись О. О.
Published: April 2022

У навчальному посібнику представлено досвід навчальної та методичної роботи викладачів закладу вищої освіти щодо організації самостійної навчальної діяльності студентів, запровадження в освітній процес інформаційно-комунікаційних технологій. Розглянуті питання змісту, сутності й оцінки якості самостійної навчальної діяльності студентів технолого-педагогічних спеціальностей; методики розробки електронного навчального контента; моделі комбінованого й змішаного навчання; технології, форми і методи організації самостійної навчальної діяльності студентів із застосуванням інформаційно-комунікаційних технологій.
Педагогіка та психологія вищої школи
Authors: Коновал Олександр Андрійович , Туркот Тетяна Іванівна
Published: April 2022

У посібнику висвітлені загальні засади педагогіки та психології вищої школи: закономірності, принципи, форми, методи, зміст вищої екологічної освіти, традиційні та інноваційні технології навчання в сучасному ВНЗ, соціально-психологічні особливості сучасного студентства та можливості їх урахування в навчально-виховному процесі. Із сучасних позицій розкриваються вимоги до педагогічної культури викладача, його лекторської майстерності та деякі аспекти екології людини. Посібник адресований студентам-екологам вищих навчальних закладів, магістрантам, аспірантам, викладачам, слухачам курсів підвищення педагогічної кваліфікації. Його доцільно використовувати в процесі самоосвіти всім, кого цікавлять проблеми навчання і виховання студентської молоді.
Критично-конструктивний підхід до вивчення спеціальної теорії відносності в профільних класах закладів загальної середньої освіти
Authors: Коновал Олександр Андрійович , Соломенко А. О. , Слюсаренко Микола Анатолійович , Туркот Тетяна Іванівна
Published: April 2022

У посібнику обґрунтовано теоретичну модель і схарактеризовано методику розвитку критичного мислення здобувачів освіти в процесі вивчення спеціальної теорії відносності у вищій та середній школах. На конкретних прикладах розглянуто дидактичні можливості використання цієї методики під час вивчення основ релятивістської механіки на засадах вимог програм з фізики для профільних класів закладів загальної середньої освіти. Запропоновано моделі розв’язання задач, завдання для контролю та самоконтролю знань, що орієнтовані на розвиток критичного мислення суб’єктів навчальної діяльності. Посібник призначений для студентів фізичних спеціальностей університетів, викладачів закладів вищої педагогічної освіти, слухачів інститутів післядипломної педагогічної освіти, вчителів-практиків, аспірантів і докторантів, які досліджують проблеми розвитку критичного мислення особистості в теоретичному та праксеологічному аспектах.
Біогеоценотичний покрив ландшафтно-техногенних систем Кривбасу
Authors: Сметана О. М. , Перерва В. В.
Published: April 2022

Розглянуто особливості формування біогеоценотичного покрову (БП) за умов потужного техногенного навантаження. Проаналізовано структури та визначено еколого-ценотичну роль рослинності у БП ландшафтно-техногенних систем (ЛТС) Кривбасу. Встановлено характерні ознаки грунтового покриву даних специфічних утворень, проведено фітоіндукцію, на підставі якої виявлено індикаторні групи окремих екологічних режимів. Наведено класифікацію грунтів ЛТС регіону. Запропоновано заходи щодо оптимізації екологічної ситуації у ЛТС. Рассмотрены особенности формирования биогеоценотического покрова (БП) в условиях мощной техногенной нагрузки. Проанализированы структуры и определена эколого-ценотическая роль растительности в БП ландшафтно-техногенных систем (ЛТС) Кривбасса. Установлены характерные признаки почвенного покрова данных специфических образований, проведена фитоиндукция, на основе которой выявлены индикаторы группы отдельных экологических режимов. Приведена классификация почв ЛТС региона. Предложены мероприятия по оптимизации экологической ситуации в ЛТС.
Comparative verse studies in Russia and globally
Authors: Polilova Vera
Published: April 2022

This survey discusses the place of comparative verse studies among contemporary linguistic and philological disciplines. Its purpose is to give an outline of the history of comparative prosody, present the current trends in comparative research of verse in Russia and abroad, and conceptualize comparative verse studies as an autonomous field at the crossroads of verse theory, history of versifi cation, linguistics, translation studies, and comparative literature. We focus on what is similar and what is diff erent between the statistical-stochastic study of verse, generative metrics, and descriptive translation studies in their attitudes toward a comparative analysis of verse forms. Our survey traces the common roots and the logic of the development of various research trajectories of this discipline and outlines prospects for further studies.
Explore the Mechanism of β-Asarone on Improving Cognitive Dysfunction in Rats with Diabetic Encephalopathy
Authors: Cai Jingwen , Cai Ming , Xia Wenwen , Jiang Lanlan , Song Hang , Chen Xiangtao
Published: April 2022

Background:

The number of people with diabetes is increasing, and many patients have significantly impaired cognitive function. For patients with diabetic encephalopathy (DE), simply lowering blood sugar does not improve learning and memory. Studies have shown that β-asarone can significantly improve cognitive impairment in patients with DE, but the specific mechanism of action is unclear.

Objective:

This experiment hopes to use a variety of experimental methods to clarify the protective effect and mechanism of β-asarone on brain neurons during the development of DE disease.

Methods:

A high-sugar and high-fat diet and streptozotocin injection-induced DE rat model was used. β-asarone was administered for four weeks. The experiment used the Morris water maze test, biochemical index detection, and many methods to evaluate the neuroprotective effect of β-asarone on DE rats from various aspects and understand its mechanism.

Results:

β-asarone reduced neuronal cell damage and significantly improved the learning and memory ability of DE rats. In addition, β-asarone can reduce the oxidative stress response and amyloid-β accumulation in the brain of DE model rats and increase the content of brain-derived neurotrophic factor (BDNF) in the brain tissue, thereby reducing neuronal cell apoptosis and playing a protective role.

Conclusion:

β-asarone can reduce the accumulation of oxidative stress and amyloid-β in the brain, increase the content of BDNF, reduce the apoptosis of neuronal cells, and exert neuronal protection, thereby improving the learning and memory ability of DE model rats.
The effects of transformational leadership on perceived organizational support and organizational identity
Authors: Dinc Muhammet Sait , Zaim Halil , Hassanin Mohaned , Alzoubi Yehia Ibrahim
Published: April 2022

BACKGROUND: This study examines the relationship among transformational leadership dimensions, perceived organizational support, and organizational identity in the banking sector which has been scarce theoretically and tested empirically in a Turkish context. OBJECTIVE: The purpose of this study to explore the impact of transformational leadership on perceived organizational support and organizational identity. It is predicted that transformational leadership will stimulate organizational identity of employees working in banking sector through their perceived organizational support. METHODS: Using the survey method, 227 responses were collected from employees. A partial least squares structural equation model was constructed to test the reliability and validity of the measurement and the structural model. RESULTS: The study results show that inspirational motivation and individual consideration dimensions of transformational leadership are found to influence employees perceived organizational support whereas perceived organizational support has a strong effect on employees’ organizational identity. However, perceived organizational support is found to mediate the relationship between inspirational motivation dimension of transformational leadership and organizational identity. The study also found a significant impact of individual consideration dimension of transformational leadership on employees’ organizational identity. CONCLUSIONS: We believe that strong genuine organizational identity should result in organizational commitment. In the long run, we need to keep caring and addressing the maturity of individual consideration in the relationship between the employee and the organization within transformational leadership model.
Automatic Classification of Subjects of the PSEN1-E280A Family at Risk of Developing Alzheimer’s Disease Using Machine Learning and Resting State Electroencephalography
Authors: García-Pretelt Francisco Javier , Suárez-Relevo Jazmín Ximena , Aguillon-Niño David Fernando , Lopera-Restrepo Francisco Javier , Ochoa-Gómez John Fredy , Tobón-Quintero Carlos Andrés
Published: April 2022

Background: The study of genetic variant carriers provides an opportunity to identify neurophysiological changes in preclinical stages. Electroencephalography (EEG) is a low-cost and minimally invasive technique which, together with machine learning, provide the possibility to construct systems that classify subjects that might develop Alzheimer’s disease (AD). Objective: The aim of this paper is to evaluate the capacity of the machine learning techniques to classify healthy Non-Carriers (NonCr) from Asymptomatic Carriers (ACr) of PSEN1-E280A variant for autosomal dominant Alzheimer’s disease (ADAD), using spectral features from EEG channels and brain-related independent components (ICs) obtained using independent component analysis (ICA). Methods: EEG was recorded in 27 ACr and 33 NonCr. Statistical significance analysis was applied to spectral information from channels and group ICA (gICA), standardized low-resolution tomography (sLORETA) analysis was applied over the IC as well. Strategies for feature selection and classification like Chi-square, mutual informationm and support vector machines (SVM) were evaluated over the dataset. Results: A test accuracy up to 83% was obtained by implementing a SVM with spectral features derived from gICA. The main findings are related to theta and beta rhythms, generated in the parietal and occipital regions, like the precuneus and superior parietal lobule. Conclusion: Promising models for classification of preclinical AD due to PSEN-1-E280A variant can be trained using spectral features, and the importance of the beta band and precuneus region is highlighted in asymptomatic stages, opening up the possibility of its use as a screening methodology.
Learning From Mistakes: Cognitive and Metabolic Correlates of Errors on Picture Naming in the Alzheimer’s Disease Spectrum
Authors: Isella Valeria , Rosazza Cristina , Ferri Francesca , Gazzotti Maria , Impagnatiello Valentina , Mapelli Cristina , Morzenti Sabrina , Crivellaro Cinzia , Appollonio Ildebrando M. , Ferrarese Carlo
Published: April 2022

Background: Analysis of subtypes of picture naming errors produced by patients with Alzheimer’s disease (AD) have seldom been investigated yet may clarify the cognitive and neural underpinnings of naming in the AD spectrum. Objective: To elucidate the neurocognitive bases of picture naming in AD through a qualitative analysis of errors. Methods: Over 1000 naming errors produced by 70 patients with amnestic, visuospatial, linguistic, or frontal AD were correlated with general cognitive tests and with distribution of hypometabolism on FDG-PET. Results: Principal component analysis identified 1) a Visual processing factor clustering visuospatial tests and unrecognized stimuli, pure visual errors and visual-semantic errors, associated with right parieto-occipital hypometabolism; 2) a Concept-Lemma factor grouping language tests and anomias, circumlocutions, superordinates, and coordinates, correlated with left basal temporal hypometabolism; 3) a Lemma-Phonology factor including the digit span and phonological errors, linked with left temporo-parietal hypometabolism. Regression of brain metabolism on individual errors showed that errors due to impairment of basic and higher-order processing of object visual attributes, or of their interaction with semantics, were related with bilateral occipital and left occipito-temporal dysfunction. Omissions and superordinates were linked to degradation of broad and basic concepts in the left basal temporal cortex. Semantic-lexical errors derived from faulty semantically- and phonologically-driven lexical retrieval in the left superior and middle temporal gyri. Generation of nonwords was underpinned by impairment of phonology within the left inferior parietal cortex. Conclusion: Analysis of individual naming errors allowed to outline a comprehensive anatomo-functional model of picture naming in classical and atypical AD.
Spillover: The Approval of New Medications for Alzheimer’s Disease Dementia Will Impact Biomarker Disclosure Among Asymptomatic Research Participants
Authors: Mozersky Jessica ,   on behalf of AGREED, Roberts J. Scott , Rumbaugh Malia , Chhatwal Jasmeer , Wijsman Ellen , Galasko Douglas , Blacker Deborah
Published: April 2022

In this article we address how the recent, and anticipated upcoming, FDA approvals of novel anti-amyloid medications to treat individuals with mild Alzheimer’s disease (AD) dementia could impact disclosure of biomarker results among asymptomatic research participants. Currently, research is typically the context where an asymptomatic individual may have the option to learn their amyloid biomarker status. Asymptomatic research participants who learn their amyloid status may have questions regarding the meaning of this result and the implications for accessing a potential intervention. After outlining our rationale, we provide examples of how current educational materials used in research convey messages regarding amyloid positivity and the availability of treatments, or lack thereof. We suggest language to improve messaging, as well as strengths of current materials, in addressing these issues for research participants. Although novel medications are currently only approved for use among symptomatic individuals, their availability may have implications for disclosure among asymptomatic research participants with evidence of amyloid deposition, who may be especially interested in information on these interventions for potential prevention, or future treatment, of mild cognitive impairment or dementia due to AD.
A cross-layer based optimized feature selection scheme for intrusion detection in wireless sensor network
Authors: Singh Ghanshyam , Gavel Shashank , Raghuvanshi Ajay Singh
Published: April 2022

The Wireless Sensor Networks (WSNs) contain a significant quantity of sensor nodes that computes and communicates for data transmission. The data packet sensed and transmitted contains various cross layer feature set that includes many important information. Many essential aspects, which include storage capability, consumption of energy, and, computational power should be taken into account while dealing with the data packets. On the other hand, many past researchers have carried out their work in order to detect intrusion utilizing cross-layer packets but fail in detecting them at the same time. Cross-layer and feature selection techniques play a key role in building an efficient Intrusion Detection System (IDS). An advantage of using the cross-layer technique is to achieve a higher correlation among different layers of the protocol so that one layer can use the parametric information of the other layer by breaking the traditional layer barriers. In this work, we propose a cross-layer based multi-feature selection model for intrusion detection in WSNs. Firstly, an optimized multi-feature selection algorithm is proposed for selecting efficient and useful features from the cross-layered architecture of the network. Secondly, a multi class intrusion detection model is proposed for the classification of different cross-layer based intrusion in the network. The proposed algorithm is developed for providing total security to cross-layer based networks by selecting prominent features and detecting intrusion at the same time. The simulation results are utilizing on real-time intrusive data from the network by analyzing the proposed model.
RETRACTED: HSR’s time-varied influence on regional tourism development: Determining the time point for post-evaluating an HSR project’s hysteretic effect on the tourism economy
Authors: Li Mingwei , Chen Juan
Published: April 2022

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Zero trust access authorization and control of network boundary based on cloud sea big data fuzzy clustering
Authors: Zhao Li , Sun Meng , Yang Binbin , Xie Junpeng , Feng Jiqiang
Published: April 2022

With the digital transformation of enterprises, the traditional security defense technology has been unable to meet the security requirements of enterprises, and the data security and privacy protection have brought great challenges to the Internet. Therefore, taking zero trust as the security concept and taking the network boundary as the best practice landing technology architecture, this paper studies the zero trust access authorization and control of network boundary based on cloud big data fuzzy clustering of. Through the network stealth technology, it constructs a virtual boundary for the enterprise, uses the cloud big data fuzzy clustering algorithm to mine the user behavior related data, and designs the trust evaluation mechanism to obtain the user trust level. The dynamic access authorization control mechanism is designed to judge the access requests in and out of the permission boundary. Combined with the user’s trust level, the legal requests and illegal requests are distinguished to complete the zero trust access authorization and control of network boundary. Experimental results show that: the method can accurately control the access authorization of the network boundary, improve the success rate of access authorization and control interaction; the interception rate of illegal access is high, and it has high securit.
The study of Letrozole adsorption upon CCT nanotube: A DFT/TD-DFT and spectroscopic (excited states and UV/Vis)
Authors: Masnabadi Nasrin
Published: April 2022

In this research, the geometric structure of LTZ and CCT (5,0) was optimized with B3LYP/6-31G* method using the Gaussian 09W program package to investigate the weak interaction of Letrozole (LTZ) and carbon carbon nanotube (CCT). According to the calculation of the release energy, it was found that the drug delivery process is desirable. Also, the structural properties of the title compounds were assessed by thermodynamic and frontier molecular orbital (FMO) parameters. In this study, a series of measures have been performed to detect changes in drug loading properties and non-bonding interactions between the LTZ and CCT (5,0) nanotube. The non-bonding interaction effects of LTZ and CCT over the electronic properties were also evaluated and argued. The research is based on the fact that studies can help to understand the interaction between the LTZ drug and CCT (5,0) nanotube and the development of CCT-based drug release systems. This research aimed to determine variations in electronic properties of anticancer LTZ drug in presences CCT. Then, the reactivity and stability behavior of LTZ drug and on CCT to be examined by density functional theory (DFT). Then, frontier molecular orbital (FMO) and noncovalent interaction (NCI) analyses were performed, which decrease in reactivity described increase in the stability of LTZ drug.
Antimicrobial effects of Cynara scolymus essential oil: In vitro analysis
Authors: Karimzadeh Mostafabadi Behnam , Ataie Kachoie Mehrdad , Rahimi Ebrahim
Published: April 2022

By benefits of using silicon and vermicompost based biofertilizers and also induction of drought stress for growing more efficient medicinal plants, we investigated such issues on growing Cynara scolymus ( C. scolymus), as one of the most significant edible medicinal plants. In this regard, the antimicrobial effects of grown C. scolymus essential oil was investigated against some foodborne pathogens. Different concentrations of silicon and vermicompost with and without drought stress were considered for growing the plant and the extracted essential oils were extracted to examine their antimicrobial effects against different bacterial agents. Using vermicompost and silicon and 50% moisture discharge yielded significant increase in the mean diameter of growth inhibition zone and significant decrease in the minimum inhibitory concentration of tested bacteria ( P < 0.05). The highest diameters of the inhibition zones of S. aureus, S. saprophyticus, P. aeruginosa, S. dysenteriae, and S. typhi were found for C. scolymus essential oil treated with 8 mmol silicon and conventional irrigation (14.92 mm), 4 mmol silicon and 50% moisture discharge (15.28 mm), 50% vermicompost and 50% moisture discharge (15.71 mm), 8 mmol silicon and conventional irrigation (17.34 mm) and 25% vermicompost, and 50% moisture discharge (15.48 mm), respectively. Antimicrobial effects of some treatments of C. scolymus were higher than some kinds of referenced antibiotics such as erythromycin. These findings could be used for the production of antibiotic drugs for specific purposes against certain bacteria.
Al2O3-coated LiNi0.8Co0.15Al0.05O2/graphene composite as a high-performance cathode material for lithium-ion battery
Authors: Loghavi Mohammad Mohsen , Babaiee Mohsen , Eqra Rahim
Published: April 2022

A cathode material composite containing Al2O3-coated LiNi0.8Co0.15Al0.05O2 (NCA) and graphene was prepared via a combination of ultrasonication and mechanical ball milling. No changes were observed in the crystalline structure of this material relative to the bare and Al2O3-coated LiNi0.8Co0.15Al0.05O2 materials based on the XRD spectrum. SEM images indicated that graphene was well distributed between the active material particles. The composite material was compared with the bare and Al2O3-coated active materials by electrochemical tests to evaluate its performance in the lithium-ion battery. The resistance values of the solid-electrolyte interphase layer and charge transfer were investigated during cycling by electrochemical impedance spectroscopy. The composite material provided the lowest resistance values with high stability during cycling. The capacity retention of the composite material was 27.7% more in comparison to the bare material during 50 cycles of charge/discharge at a 0.5C rate. Remarkably, the rate capability was improved by using the composite material, with a specific capacity of over 130.9 mAh g–1 at a 3C rate, which means delivering 62.9 mAh g–1 more capacity than the bare NCA. Graphene improved capacity retention and rate capability through the creation of a protective layer on the particles and providing a conductive medium in the electrode structure.
Impact of personalized nutritional intervention on nutritional status and quality of life of maintenance hemodialysis patients with protein energy wasting
Authors: Nagy Eman , Tawfik Mona , Abdelsalam Noha , El-kannishy Ghada , Sayed-Ahmed Nagy , Mahmoud Mostafa
Published: April 2022

BACKGROUND: Protein energy wasting (PEW) is a common multifactorial problem affecting maintenance hemodialysis (MHD) patients. OBJECTIVES: We aimed to explore the impact of personalized nutritional intervention on nutritional status and quality of life (QOL) in MHD patients. METHODS: Interventional study included 18 MHD patients suffering from PEW. They were subjected to personalized nutritional intervention for 6 months according to Kidney Disease Outcomes Quality Initiative (KDOQI) Clinical Practice Guidelines (2000). QOL was evaluated by using the Kidney Disease Quality of Life (36 KDQOL-36). Nutritional status and QOL of those patients were re-assessed after 6 months and compared to those at the baseline. RESULTS: Fourteen patients completed six months of the study. Following such intervention, half of these patients became no longer suffering from PEW (responder group). Most of the nutritional and QOL data improved in the responder in contrary to the non-responder group of patients. The baseline level of parathyroid hormone (PTH) was significantly higher but physical health was significantly lower in non-responder than responder groups. CONCLUSIONS: Implementation of an internationally acknowledged nutritional program could improve the nutritional status and QOL of MHD patients with PEW. Moreover, PTH level, and physical health of the studied patients could contribute to the positive response to nutritional intervention.
The Relationship between Fiscal and Monetary Policies in Colombia: An Empirical Exploration of the Credit Risk Channel
Authors: Lozano-Espitia Ignacio , Arias-Rodríguez Fernando
Published: April 2022

This paper aims to provide evidence on the relationship between fiscal and monetary policy in Colombia through an empirical exploration of the credit risk channel. Under this approach, fiscal policy plays an important explanatory role in the sovereign risk premium, which, in turn, could aﬀect the exchange rate and inﬂation expectations. The Central Bank reacts to inﬂation expectations using the policy interest rate; consequently, such reaction could be indirectly inﬂuenced by fiscal behavior. Using monthly data from January 2003 to December 2019, we estimate both jointly and independently the reduced-form core equations of a system that describes the credit risk channel in a small open economy. Our findings are in line with the model predictions. Fiscal policy aﬀected the country’s sovereign risk during this period, but only slightly. Hence, there is insufcient evidence to sustain the idea that monetary policy has been signifcantly inﬂuenced by government fiscal management.
Estado actual de la exploración de fosfatos en Colombia
Authors: Hubach Enrique
Published: April 2022

Breve referencia a la búsqueda infructuosa de potasa en los yacimientos de sal en Cundinamarca. Estos yacimientos son excemas de sal, es decir una acumulación de esa materia plástica en zonas débiles o fracturadas. Varios depósitos de sal de la Sabana de Bogotá se hallan en el declive de domos, en la parte alta. Se ha encontrado sal in situ en el nivel Cenomaniano Superior del anticlinal de Tabio, a unos 8 km al N de la población del mismo nombre. En el borde de la cordillera Oriental hacia los Llanos Orientales se presenta un banco de sal en Upín, al Norte de Villavicencio que se halla en el Valanginiano y que tiene al­gunos metros de espesor. Este banco no manifiesta la participación de potasio. Una perforación hecha en la salina principal de la -Sabana de Bogotá, la de Zipaquirá, a 160 m de profundidad (sin alcanzar el fondo) no registró muestras de sales potásicas. Como no hay otros yacimientos de sal en Colombia, hay que concluir que los presentes deben su existencia a la disecación pasajera de zonas del mar cretácico sin precipitación de la lejía potásica.
Informe de las labores del Servicio Geológico Nacional en el mes de febrero de 1953
Authors: Hubach Enrique
Published: April 2022

Se presenta un informe de las labores del Servicio Geológico Nacional en el mes de febrero de 1953. Inicialmente, se mencionan conceptos sobre propuestas de petróleos hechas por el Dr. Sandoval, conceptos sobre informes anuales de la Concesión Becerril de la International Petroleum, luego se enumeran los informes rendidos durante el mes: No. 897 Hubach, E., No. 898 Hubach, E., No. 899 Hubach, E., No. 901 Hubach, E., No.902 Diezemann, W., No. 903 Diezemann, W. Se presentan los informes mensuales de la sección de fotogeología, No. 904 Nelson, H.W, el informe de la sección de petrografía, paleontología, paleobotánica, Museo Geológico. Finalmente, se presentan informes sobre servicios regionales como lo son la Planta Metalúrgica Nacional, el Laboratorio de Fomento Minero de Pasto, el Laboratorio de Fundición y Ensayos de Quibdó y el Edificio para el Servicio Geológico.
Estudio petrográfico de cinco rocas provenientes de las cabeceras del río Humea Chico
Authors: Wolfgong Nelson Hans
Published: April 2022

Descripción de secciones delgada con microscopio petrográfico de muestras de roca de las cabeceras del río Humea Chico, mina la Aurora (Ubalá) con resultados de análisis de Au, Ag y Pb, y mapas de localización.
Labores del Servicio Geológico Nacional en marzo de 1953
Authors: Hubach Enrique
Published: April 2022

Este artículo contiene resúmenes de las labores realizadas en marzo de 1953. 1) estudio para abastecer al corregimiento de Puerto Bogotá con aguas subterráneas por medio de aljibes construidos en el lado oriental del río Magdalena. 2) estudios para la perforación de pozos en diferentes lugares de Cundinamarca que pueden ser óptimos para uso doméstico de las fincas aledañas. 3) informes en preparación sobre los yacimientos de cobre, zinc y plomo de la provincia del Guavio, Cundinamarca que pueden ser de aprovechamiento nacional; 4) informes sobre el aprovechamiento de materias terrosas entre Cartago y Zarzal en el Valle.
El artículo presenta informes mensuales en: 1) paleontología con la clasificación de la familia Pulchellidae del catálogo de amonitas de Colombia; 2) fotogeología con el dibujo de las planchas geológicas de Cundinamarca y dos planchas topográficas; 3) Informe de petrografía con el estudio de secciones delgadas de Coyaima y Natagaima en el Tolima; 4) informe de paleobotánica con análisis palinológicos de la Formación Guaduas. 5) Informe del Museo Geológico Nacional con la elaboración de una colección de fósiles y el catálogo de las muestras nuevas.
Por último, el artículo presentan los servicios regionales prestados por la entidad, tales como estudios de carbón, trabajos de exploración de yacimientos de azufre, una visita de interventoría a la Yesera Ecodera y el análisis de las muestras de minerales tomadas en La Equis, en la carretera Quibdó-Bolívar.
La región metalífera de San Joaquín, municipio de Mercaderes, departamento de Cauca
Authors: Bueno Jesús
Published: April 2022

Por disposición del Ministerio de Minas y Petróleos, el suscrito intervino en la práctica de diligencias de carácter especial en la region minera de la Esmeralda en el municipio de Mercaderes (Cauca). Esta comisión sirvió para hacer un reconocimiento somero de la zona y, en particular, del yacimiento metalífero que está en exploración. Los datos que suministra este informe como resultado de ese reconocimiento tienen, dentro de su valor meramente preliminar, el objeto de señalar el interés que tiene ese territorio para exploraciones mineras relacionadas principalmente con zinc, plomo y cobre.
El Cretáceo superior en la región de Girardot
Authors: Bürgl Hans , Dumit Tobón Yolanda
Published: April 2022

La ciudad de Girardot está situada en un sinclinal terciario al Norte, Este y Oeste por rocas del Cretáceo Superior, las cuales comprenden una serie completa desde el Tnroniano Superior hasta el Maestrichtiano.
Dos secciones del Cretáceo Superior han sido descritas en detalle en cuanto a su litología y a su fauna de moluscos y foraminíferos, la una situada al Oeste (Girardot-Nariño) y la otra al Este (Girardot-Melgar). La determinación de la edad de los horizontes está basada, en lo posible, en amonitas, aunque del estudio de los foraminíferos se obtuvieron valiosos datos.
El Turoniano y el Coniaciano se dividen en algunos horizontes litológicos y son ricos en amonitas y lamelibranquios, mientras que la microfauna es muy pobre, conteniendo casi exclusivamente formas planctónicas. El Coniaciano Superior está presentado por la “segunda lidita”; las margas y arcillas situadas encima de esta, no contienen moluscos, pero si una microfauna muy rica y uniforme, la cual consideramos de edad Santoniana. Dichas margas y arcillas están superpuestas por la “Primera lidita” y por margas y arcillas arenosas, caracterizadas por la presencia de amonitas campanianas y por una microfauna muy rica en varias especies de Siphogonerinoides. Todos los horizontes desde el Turoniano hasta la cima del Campaniano, están conectados por transiciones litológicas y microfaunísticas las cuales indican una sedimentación continua durante estos periodos. En contraste, observamos un hiato encima del Campaniano, seguido al principio del Maestrichtiano por una transgresión nueva, caracterizada por la aparición de Siphogenerinoides plummeri o bramtellei. Hacia arriba los de ositos maestrichtianos se vuelven gradualmente más arenosos y más continentales. Algunas intercalaciones finas, arcillosas, con Siphogenerinoides plummeri determinan periodos cortos de inundación marinas.
En comparación con el Cretáceo Superior de los alrededores de Bogotá, el de la región de Girardot es más rico en cal y menos arenoso que aquel y mucho más rico de fósiles. El espesor del Santoniano (y del Coniaciano?) es igual tanto en la región de Bogotá como en la de Girardot y en cambio el del Campaniano y del Maestrichtiano es mucho mayor cerca de Girardot que de Bogotá; esto indica que la zona de máxima sedimentación en el geosinclinal Cretáceo se movió al principio del Campaniano de una posición más oriental hacia la hoya del río Magdalena, donde después fueron depositados sedimentos de un mayor espesor en el Terciario. Este traslado de eje de sedimentación refleja evidentemente la iniciación del solevantamiento de la cordillera Oriental favorecido por una relativa acentuación del hundimiento en la hova del Madalena. El mismo fenómeno del hundimiento se observa en el borde oriental (Llanos) de la cordillera Oriental a partir del Oligoceno.
Fotogeología y su aplicación a la exploración petrolera
Authors: Salas Guillermo P.
Published: April 2022

El excelente trabajo publicado en el N° 11-12 del Vol. V pp. 369-423 en noviembre de 1953, por el recién titulado Ing. Geólogo Juan B. Puig, no sólo es de actualidad y de alto valor para el adelanto técnico en materia de exploración geológica, sino que viene a llenar un enorme hueco. en la literatura geológica, en castellano, respecto del uso de la aerofotografía aplicada a la técnica de exploración.
Se presentan en dicho trabajo algunos puntos que no está por demás discutir, con objeto de ampliar los conceptos en él emitidos.
Micropaleontología y estratigrafía de la sección Arroyo Saco, Depto. del Atlántico
Authors: Bürgl Hans , Barrios M. Margoth , Röström Ann Mane
Published: April 2022

Este informe trata la litología, micropaleontología y estratigrafía de la sección de 1730 m de espesor, expuesta en el Arroyo Saco en el Depto. del Atlántico, unos 37 km SW de Barranquilla.
Las capas expuestas pertenecen al Mioceno, desde la parte basal hasta la inferior del Mioceno Medio y están inclinadas hacia el Este con un buzamiento de 10-15º.
En esta serie se pueden reconocer algunos ciclos mayores de sedimentación. Cada uno principia con arcillas pelágicas con foraminíferos que pasan hacia arriba a arcillas arenosas y finalmente a arenas litorales y areniscas, en parte calcáreas sin foraminíferos, pero ricas en cambio en moluscos. De tal manera, los foraminíferos están casi restringidos a la parte inferior y los moluscos a la superior de cada ciclo.
Los mayores ciclos corresponden al 3) Mioceno Medio rojo (= ? Helveciano), 2) Mioceno Inferior alto (= ? Burdigaliano), 1) Mioceno Inferior bajo (= ? Aquitaniano).
Los ciclos 2 y 3 están subdivididos en unidades secundarias.
Los moluscos colectados en el Arroyo Saco están descritos en M. Barrios Monroy 1955. La parte sistemática de este informe trata de los foraminíferos de esta sección, la mayoría de los cuales están figurados en cinco láminas. Los microfósiles son miembros típicos de la fauna de la provincia caribe.
A palynological systematic nomenclature
Authors: Van der Hammen Thomas
Published: April 2022

The present article deaIs with a new artificial palynological nomenclature. The genera and generic names of pollengrains are based on the pollen-types of IVERSEN & TROELS-SMITH (1950) and the subgenera and sub-generic names on the sculpture-types of the same authors. The main part of the theoretically possible genera and some of the sub-genera are described with their type species.
For spores a similar system is proposed, but the genera are n0t described here with their type-species, as many spore-genera are established already from the Paleozoic.
Descripción de algunos géneros y especies de polen y esporas fósiles
Authors: Van der Hammen Thomas
Published: April 2022

En una publicación anterior dimos una descripción corta y una clasificación provisional de algunas especies del Maestrichtiano (VAN DER HAMMEN 1954)
Ahora que establecimos definitivamente el sistema de clasificación damos aquí una descripción completa de algunas de estas especies y además de varias especies nuevas del Terciario, ya que necesitamos referirnos a estas especies en unas publicaciones sobre cambios climáticos que aparecerán en breve. Por la misma razón describimos algunos de los géneros de esporas propuestos en el anterior artículo (VAN DER HAMMEN 1956)
Description of some genera and species of fossil pollen and spores
Authors: Van der Hammen Thomas
Published: April 2022

In a former publication we gave a short description and provisional classification of number of species of Maestrichtian age (VAN DER HAMMEN, 1954). As we have established now more definitely the classification system, we give here now the complete description of some of these species and moreover of some new species from the Tertiary, as we need to mention those species in some publications on climatic changes which will soon appear. For the sa.me reason we describe some of the spore-genera we proposed in the former publication (VAN DER HAMMEN, 1956).