bluuebunny/crossref_metadata_2025 huggingface dataset:
RAZVOJ TREĆE MISIJE UNIVERZITETA U SRBIJI
Authors: Grandić Radovan , Bosanac Maja
Published: October 2018

Univerziteti su još od svog osnivanja u srednjem veku bili neodvojivi od društva u kojem deluju; međutim, u različitim istorijskim periodima prioritet se davao različitim misijama. Pored nastave i istraživanja kao osnovnih univerzitetskih misija, pod trećom misijom univerziteta podrazumeva se odnos univerziteta i zajednice. U radu se opisuju društvene promene koje dovode do otvaranja univerziteta prema spoljašnjem okruženju. Polazeći od stanovišta prema kojem se treća misija univerziteta sastoji od dve dimenzije – društvene, civilne i ekonomske, koje treba da budu ravnopravne - kao cilj rada postavlja se sagledavanje perspektive razvoja treće misije univerziteta u Srbiji, sa posebnim akcentom na društvenu i civilnu dimenziju. Cilj je operacionalizovan kroz dva zadatka: prvi se odnosi na definisanje treće misije i analizu internacionalnog projekta Institucionalni okvir za razvoj treće misije univerziteta u Srbiji koji se trenutno realizuje; drugi zadatak jeste komparacija dve paradigme kroz koje može da se realizuje treća misija univerziteta, služenje zajednici (community service), nasuprot paradigmi zalaganja u zajednici (community engagement). Kao zaključak rada ističe se kako postoje osnove za aktuelizaciju proučavanja treće misije univerziteta u Srbiji, ali se primećuje veća usmerenost ka komercijalnoj i ekonomskoj u odnosu na društvenu i civilnu dimenziju.
El 50º Aniversario del Instituto de Medicina Tropical Alexander Von Humboldt, Universidad Peruana Cayetano Heredia
Authors: Llanos Cuentas Alejandro
Published: October 2018

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Perú al pie del orbe. Homenaje a César Vallejo por los 80 años de su muerte
Authors: Pantigoso Pecero Manuel
Published: October 2018

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Tobolsk District Library activity in 1923-1930
Authors: Zagorodnyuk N. I. , Murashova N. A.
Published: October 2018

The article first considers the historical experience of Tobolsk District Library formation and development in 1923-1930. It characterizes the forms and methods of library practice, the specifics of working with other regional libraries, especially the personnel policy. The regional libraries management was carried on under difficult natural geographical conditions: the district area was more than 1,3 million square kilometers, a significant distance from administrative centers and settlements of the district, instability of socio-political processes, low level of socio-economic development, etc. Operating from 1923 to 1930, the district library was assigned the following tasks: combining libraries, coordination of their activities, assistance in work organization, books provision, creating teaching materials, and others. During the studied period, libraries experienced difficulties related to low funding, poor working conditions, lack of electricity, insufficient supply with literature. New forms of library work required additional funding, training and retraining. These problems have not been resolved. Methodological assistance was provided in various forms: meetings, group classes, by correspondence. In October 30, 1929 the CPSU (b) adopted a resolution «On the library activity improvement», which gave a negative assessment of the library business state in the USSR. In 1930 the work of the District Library was recognized as unsatisfactory. These shortcomings in the work fully coincided with the all-Union ones. Nevertheless, a small team carried on work to preserve the existing libraries and create new ones. Much attention was paid to the rural reading rooms, mobile libraries, and bibliography activity.
Analytical characteristics of a document flow of dissertations on library science in the USA and Canada
Authors: Romanov P. S.
Published: October 2018

The article discusses the results of studying a document flow of English-speaking dissertations in the field of library science, bibliography and bibliology, as well as information management for a centenary period. To solve the research tasks, a scientometric approach has been applied including sources, bibliometric, historical methods, as well as elements of the content analysis. The author has carried out a thematic selection of English-language dissertations from several foreign sources, in particular, databases by UMIProQuest Co and some others. The paper reveals development trends of library information science abroad for hundred years. The author compiled and published an annotated list of English-language theses on this topic with the translation into Russian.
A Spectrum Sharing Framework for Intelligent Next Generation Wireless Networks
Authors: de Figueiredo Felipe A. P. , Mennes Ruben , Jiao Xianjun , Liu Wei , Moerman Ingrid
Published: October 2018

The explosive emergence of wireless technologies and standards, covering licensed and unlicensed spectrum bands has triggered the appearance of a huge amount of wireless technologies, with many of them coexisting in the same band. Unfortunately, the wireless spectrum is a scarce resource, and the available frequency bands will not scale with the foreseen demand for new capacity. Certain parts of the spectrum, in particular the license-free ISM bands, are overcrowded, while other parts, mostly licensed bands, may be significantly underutilized. As such, there is a need to introduce more advanced techniques to access and share the wireless medium, either to improve the coordination within a given band, or to explore the possibilities of intelligently using unused spectrum in underutilized (e.g., licensed) bands. Therefore, in this paper, we present an open source SDR-based framework that can be employed to devise disruptive techniques to optimize the sub-optimal use of radio spectrum that exists today. Additionally, we describe three use cases where the proposed framework can be employed along with intelligent algorithms to achieve improved spectrum utilization.
What if the ‘Anthropocene’ is not Formalised as a  New Geological Series/Epoch?
Authors: Rull Valenti
Published: October 2018

In the coming years, the Anthropocene Working Group (AWG) will submit its proposal on the ‘Anthropocene’ as a new geological epoch to the International Commission on Stratigraphy (ICS) for approval. If approved, the proposal will be send to the International Union of Geological Sciences (IUGS) for ratification. If the proposal is approved and ratified, the ‘Anthropocene’ will be formalised and the Holocene Series/Epoch will be officially terminated. Currently, the ‘Anthropocene’ is a broadly used term and concept in a wide range of scientific and non-scientific situations and, for many, the official acceptance of this term is only a matter of time. However, the AWG proposal, in its present state, seems to not fully meet the ICS requirements for a new geological epoch. This paper asks what could happen if the current ‘Anthropocene’ proposal is not formalised by the ICS/IUGS. The possible stratigraphic alternatives are evaluated on the basis of the more recent literature and the personal opinions of distinguished AWG and ICS members. The eventual impact on environmental sciences and on non-scientific sectors, where the ‘Anthropocene’ seems already firmly rooted and de facto accepted as a new geological epoch, are also discussed.
Carbon Capture and Storage. A Case Study of Mineral Storage of CO2 in Greece
Authors: Kelektsoglou Kyriaki
Published: October 2018

While the demand in reduction of CO2 increases, the need for CO2 sequestration processes is very high. One promising technology is the Carbon Capture and Storage (CCS). In this paper we refer to several papers which study the three main steps in CCS chain. CO2 capture technologies, CO2 transportation to the storage sites and the very critical step the CO2 storage. Recently a novel method (mineral carbonation) for CO2 sequestration has been proposed which is based in the reaction of CO2 with calcium or magnesium oxides or hydroxides to form stable carbonate materials. Greece is a country that emits CO2 mainly from the lignite fired power plant in Western Greece. After the study of the bibliographic references about the use of mineral carbonation process while injecting CO2 in the appropriate geological forms we concluded that there are also these forms in our country and mainly in the area near to the power plant such as in sites Vourinos and Pindos. In these sites exist minerals rich in oxides and hydroxides of Ca, Mg and Fe representing the perfect materials for mineral carbonation.
On the Arrow of Spacetime
Authors: Harvey-Tremblay Alexandre
Published: October 2018

Consistent with special relativity and statistical physics, here we construct a partition function of space-time events. The union of these two theories resolves longstanding problems in regards to time. It augments the standard description of time given by the (non-relativistic) arrow of time to one able to show the emergence of three macroscopic regimes of time: the past, the present, and the future, represented by space-like entropy, light-like entropy, and time-like entropy, respectively, and in a manner consistent with our experience of said regimes. First, using Fermi-Dirac statistics, we find that the system essentially describes a "waterfall" of space-time events. This "waterfall" recedes in space-time at the speed of light towards the direction of the future as it "floods" local space with events that it depletes from the past. In this union, an observer O will perceive two horizons that can be interpreted as hiding events behind it. The first is an event horizon, and its entropy hides events in the regions that O cannot see. The second is a time horizon, and its entropy "shields" events from O's causal influence. As only past events are "shielded", and not future events, an asymmetry in time is thus created. Finally, future events are hidden by an entropy prohibiting O from knowing the future before the present catches on.
The Relationship between Body Composition and a Gluten Free Diet in Children with Celiac Disease 
Authors: Więch Paweł , Chmiel Zdzisława , Bazaliński Dariusz , Sałacińska Izabela , Bartosiewicz Anna , Mazur Artur , Korczowski Bartosz , Binkowska-Bury Monika , Dąbrowski Mariusz
Published: October 2018

The primary and proven therapy, in cases of celiac disease (CD), is a rigorous gluten-free diet. However, there are reports of its negative effects in the form of nutritional deficiencies, obesity and adverse changes in body composition. The aim of the study was to assess the impact of a gluten free diet (GFD) on the body composition of children with CD. In a case-controlled study (n = 41; mean age 10.81 y; SD = 3.96) children with CD, in various stages of treatment, underwent medical assessment. The control group consisted of healthy children and adolescents, strictly matched for gender and age in a 1:1 case-control manner. More than half of the examined children (n = 26) followed a GFD. CD children had significantly higher mean values of the fat free mass (FFM% = 80.68 vs. 76.66, p = 0.015), and total body water (TBW% = 65.22 vs. 60.47, p = 0.012), and lower mean values of the fat mass (FM% = 19.32 vs. 23.34, p = 0.015). Children who were on a GFD presented slightly higher, but not statistically significant, mean values of FM and FFM, than children who did not follow dietary recommendations (FM [kg] = 7.48 vs. 5.24, p = 0.064; FM% = 20.81 vs. 16.73, p = 0.087; FFM [kg] = 28.19 vs. 22.62, p = 0.110). After minimum one year of a GFD, CD children showed significantly higher values of FFM [kg] (p = 0.001), MM [kg] (p < 0.001), TBW [L] (p < 0.001) and BCM [kg] (p < 0.001). Furthermore, CD children who were on a GFD presented significantly higher weight (p = 0.034) and body mass index (BMI) (p = 0.021) increase. The children adhering to a GFD demonstrate a tendency towards higher indices of selected body composition components.
S100A10 in Cancer Progression and Chemotherapy Resistance: A Novel Therapeutic Target against Ovarian Cancer
Authors: Noye Tannith , Lokman Noor , Oehler Martin , Ricciardelli Carmela
Published: October 2018

S100A10, which is also known as p11 is located in the plasma membrane and forms a heterotetramer with annexin A2. The heterotetramer, comprising of 2 subunits of annexin A2 and S100A10, activates the plasminogen activation pathway which is involved in cellular repair of normal tissues. Increased expression of annexin A2 and S100A10 in cancer cells leads to increased levels of plasmin which promote degradation of the extracellular matrix, increased angiogenesis and invasion of the surrounding organs. Although many studies have investigated the functional role of annexin A2 in cancer cells including ovarian cancer, S100A10 has been less studied. We recently demonstrated that high stromal annexin A2 and high cytoplasmic S100A10 expression is associated with a 3.4 fold increased risk of progression and 7.9 fold risk of death in ovarian cancer patients. Other studies have linked S100A10 with multidrug resistance in ovarian cancer, however, no functional studies to date have been performed in ovarian cancer cells. This article reviews the current understanding on S100A10 function in cancer with a particular focus on ovarian cancer.
Axial Compression Model for FRP Confined Concrete in Elliptical Cross Sections
Authors: Isleem Haytham F. A.
Published: October 2018

Most of the existing studies conducted on FRP-confined concrete considered circular and square concrete columns, while limited studies were on columns with rectangular sections. The studies have confirmed that the circular cross-sections exhibited higher confinement effectiveness, whereas in the case of non-circular cross-sections the efficiency of FRP confinement decreases with an increase of the sectional aspect ratio and there is no significant increase, particularly for columns with the aspect ratio of 2.0. As recently suggested by the researchers, to significantly increase the effectiveness of FRP-confinement for these columns is by modifying a rectangular section to an elliptical or oval section. According to the literature, most of the existing confinement models for FRP-confined concrete under axial compression have been proposed for columns with circular and rectangular cross-sections. However, modeling the axial strength and strain of concrete confined with FRP in elliptical cross-sections under compression is most limited. Therefore, this paper provides new expressions based on limited experimental data available in the literature. For a sufficient amount of FRP-confinement, the threshold value was proposed to be 0.02. Finally, the accuracy of the proposed model was verified by comparing its predictions with the same test database, together with those from the existing models.
Evaluation of Efficacy and Adherence to Gluten-Free Diet in Patients with Celiac Disease
Authors: Rodrigo Luis , Perez-Martinez Isabel , Lauret-Braña Eugenia , Suarez-Gonzalez Adolfo
Published: October 2018

Celiac disease (CD) is a genetically conditioned autoimmune process that appears in susceptible people. It can affect people of any age, and slightly predominates in females. It has a fairly homogenous global distribution, with an average prevalence of 1-2%, the frequency having increased in recent decades. The only effective treatment is a strict and permanent gluten-free diet (GFD), although the level of compliance with it is poor, at about 50% of cases. To monitor the effectiveness of the GFD, several procedures involving various approaches are employed: a) periodic interviews by nutritionists; b) clinical follow-up; c) serological controls of specific antibodies; d) endoscopies with collection of duodenal biopsies; e) structured questionnaires; f) determination of gluten peptides derived from gluten in feces and/or urine. All of these procedures are useful when applied, alone or in combination, depending on the cases. Some patients will only need to consult to their doctors, while others will require a multidisciplinary approach to assess their compliance with the GFD. In children, normalization of duodenal mucosa was achieved in 95% of cases within 2 years, while it is more delayed in adults, whose mucosa take longer to heal completely.
A Review on Liquid Chromatography-Tandem Mass Spectrometry Methods for Rapid Quantification of Oncology Drugs
Authors: Wong Andrea LA , Xiang Xiaoqiang , Ong Pei Shi , Ee Qin Ying Mitchell , Syn Nicholas , Ian Wee , Kumar Alan Prem , Yong Wei Peng , Sethi Gautam , Goh Boon Cher , Ho Paul Chi-Lui , Wang Lingzhi
Published: October 2018

In the last decade, the tremendous improvement in the sensitivity and also affordability of Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) have revolutionized its application in pharmaceutical analysis, resulting in wide-spread of employing LC-MS/MS for determining pharmaceutical compounds including anticancer drugs in pharmaceutical research and also industries. Currently, LC-MS/MS has been widely used to quantify small molecule oncology drugs in various biological matrices to support preclinical and clinical Pharmacokinetic studies in R & D of oncology drugs. This mini-review article will describe the state-of-the art LC-MS/MS and its application in rapid quantification of small molecule anticancer drugs. In addition, efforts have also been made in this review to address several key aspects in the development of rapid LC-MS/MS methods, including sample preparation, chromatographic separation and matrix effect evaluation.
A Specific Large-Scale Pressure Gradient Forcing for Computation of Realistic 3D Wind Fields Over a Canopy at Stand Scale
Authors: Pimont Francois , Dupuy Jean-Luc , Linn Rodman , Sauer Jeremy
Published: October 2018

Turbulent flows over and within forest canopies have recently been modeled with success using Large Eddy Simulations (LES). Validation exercises against experimental data suggest that models can be applied with a high degree of confidence for many applications, mechanical and physiological plant/atmosphere interaction analysis, seed or pollen dispersal, wildfire spread and firebrand transport, or investigation of causes of eddy-covariance technique bias. Long distances required for shear-induced turbulence to equilibrate, result in the widespread use of cyclic boundary conditions in LES atmospheric boundary layer studies. Vegetation drag dissipates air momentum in the atmosphere, but equilibrium is often achieved through compensatory momentum source, supplied by macro-scale pressure gradient forcing. Unfortunately, both classical Ekman balance or simple spatially-constant pressure gradient techniques for implementing this forcing have major drawbacks in the context of cyclic boundary conditions for the applications listed above. Among them, it is difficult to specify aspects of the mean velocity profile such as a specific desired wind velocity and direction at a reference height. In the present paper, we propose a new technique for capturing the effects of a large-scale pressure gradient force (LSPGF) that can be used at stand scale and enables simulation of realistic and specifiable wind fields. Several variants of this LSPGF are developed and analyzed here and validated against experimental data. Although this LSPGF technique is developed in the context of HIGRAD/FIRETEC wildfire simulations, LSPGF can be used for any LES wind modeling application aimed at generating detailed stand-scale wind fields with resolved turbulence and shear profiles consistent with vegetation structure in the boundary layer.
Next-generation sequencing to investigate existing and new insect associations with phytopathogenic fungal propagules
Authors: Tremblay Émilie D. , Kimoto Troy , Bérubé Jean A. , Bilodeau Guillaume J.
Published: October 2018

Understanding ecological interactions is a key in managing phytopathology. Although entomologists rely mostly on both traditional molecular methods and morphological characteristics to identify pests, next-generation sequencing is becoming the go-to avenue for scientists studying fungal and oomycete phytopathogens. These organisms sometimes infect plants together with insects. There are many relationships yet to be discovered and much to learn about how these organisms interact with one another. Considering the growing number of exotic insect introductions in Canada, a high-throughput strategy for screening those insects is already implemented by the Canadian Food Inspection Agency (CFIA). However, no plan is deployed to investigate the phytopathogenic fungal and oomycete species interacting with insects. Metagenomics analysis was performed on the preservation fluids from CFIA’s insect traps across Canada. Using the Ion Torrent PGM technology and fusion primers for multiplexing and indexing, community profiling was conducted on the different semiochemicals used in the insect traps and the various areas where these traps were placed. Internal transcribed spacer 1 (fungi and oomycetes) and adenosine triphosphate synthase subunit 9-nicotinamide adenine dinucleotide dehydrogenase subunit 9 spacer amplicons were generated. Although direct links between organisms could not be established, moderately phytopathogenic fungi (e.g., Leptographium spp. and Meria laricis) and oomycetes (mainly Peronospora spp. and Pythium spp.) unique to every type of semiochemical were discovered. The entomopathogenic yeast Candida michaelii was also detected. This project demonstrated our ability to screen for unwanted species faster and at a higher scale and throughput than traditional pathogen diagnostic techniques. Additionally, minimal modifications to this approach would allow it to be used in other phytopathology fields.
Current Status of the Sm14/GLA-SE Schistosomiasis Vaccine: Overcoming Barriers and Paradigms towards the First Anti-Parasitic Human(itarian) Vaccine
Authors: Tendler Miriam , Almeida Marilia S. , Vilar Monica M. , Pinto Patricia M. , Limaverde-Sousa Gabriel
Published: October 2018

Schistosomiasis, a disease historically associated with poverty, lack of sanitation and social inequalities, is a chronic, debilitating parasitic infection, affecting hundreds of millions of people in endemic countries. Although schistosomiasis control approach has shown that chemotherapy is capable of reducing morbidity in humans, rapid re-infection is a reminder that the impact of drug treatment on transmission control or elimination initiatives is marginal. In addition, and regardless of more than two decades of well-executed control activities based on large-scale chemotherapy, the disease is expanding in many areas including Brazil. The development of the Sm14/GLA-SE schistosomiasis vaccine is an emblematic open knowledge innovation that has successfully completed Phase I and Phase IIa clinical trials, with Phase II/III trials underway in the African continent and to be followed in Brazil. Discovery and experimental phases were long term achievements leading to a robust collection of data that are strongly supporting the presently ongoing Clinical Phase. This paper reviews the development of the Sm14 vaccine formulated with GLA-SE (Glucopyranosyl Lipid A), from the earlier experimental developments to clinical trials including the recent status of Phase II studies.
Simultaneous Forecasting of Meteorological Data Based on a Self-Organizing Incremental Neural Network
Authors: Kim Wonjik , Hasegawa Osamu ,   Department of Systems and Control Engineering, Tokyo Institute of Technology 2-12-1-S5-22 Ookayama, Meguro, Tokyo 152-8550, Japan,   Department of Systems and Control Engineering, Tokyo Institute of Technology 4259 J3-13 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan,   SOINN Inc. Cureindo-building 405, 8-4-30 Turuma, Machida, Tokyo 194-0004, Japan
Published: October 2018

In this study, we propose a simultaneous forecasting model for meteorological time-series data based on a self-organizing incremental neural network (SOINN). Meteorological parameters (i.e., temperature, wet bulb temperature, humidity, wind speed, atmospheric pressure, and total solar radiation on a horizontal surface) are considered as input data for the prediction of meteorological time-series information. Based on a SOINN within normalized-refined-meteorological data, proposed model succeeded forecasting temperature, humidity, wind speed and atmospheric pressure simultaneously. In addition, proposed model does not take more than 2 s in training half-year period and 15 s in testing half-year period. This paper also elucidates the SOINN and the algorithm of the learning process. The effectiveness of our model is established by comparison of our results with experimental results and with results obtained by another model. Three advantages of our model are also described. The obtained information can be effective in applications based on neural networks, and the proposed model for handling meteorological phenomena may be helpful for other studies worldwide including energy management system.
Mini Special Issue on Human Sensing, Modeling, and Augmentation
Authors: Tanaka Takayuki
Published: October 2018

Human work and life support are areas that provide practical applications for robotics and mechatronics technology. There is great expectation from the industry in these fields, and research and development efforts have been actively undertaken with great social impact. To support human work and life accurately, we must understand the complicated sensory, nervous, and motor control systems that enable design and development of appropriate assistive devices.

Therefore, in this mini special issue, we focus on robotics and mechatronics for human sensing, modeling, and augmentation.

The editor hopes that this special issue will attract researchers’ interest and contribute to further developments in this field.
Noether’s theorems of variable mass systems on time scales
Authors: Yan Wu , Jing-Li Fu
Published: October 2018

This paper deals with the Noether’s theory for variable mass system on time scales. The calculus on time scales unifies and extends variable mass system continuous model and discrete model into a single theory. Firstly, Hamilton’s principle of the variable mass system on time scales is given. Secondly, based on the quasi-invariance of the Hamilton’s action under a group of infinitesimal transformations, Noether’s theorem and its inverse theorem of the variable mass system on time scales are presented. Finally, two examples are given to illustrate the applications of the results.
Wall Properties and Slip Consequences on Peristaltic Transport of a Casson Liquid in a Flexible Channel with Heat Transfer
Authors: Devaki P. , Sreenadh S. , Vajravelu K. , Prasad K. V. , Vaidya Hanumesh
Published: October 2018

In this paper, the peristaltic wave propagation of a Non-Newtonian Casson liquid in a non-uniform (flexible)channel with wall properties and heat transfer is analyzed. Long wavelength and low Reynolds number approximations are considered. Analytical solution for velocity, stream function and temperature in terms of various physical parameters is obtained. The impact of yield stress, elasticity, slip and non-uniformity parameters on the peristaltic flow of Casson liquidare observed through graphs and discussed. The important outcome is that an increase in rigidity, stiffness and viscous damping force of the wall results in the enhancement of the size and number of bolus formed in the flow pattern.
Construction and Transformation of OsERA1 Gene into Expression Vector and Response of Nipponbare-OsERA1 Transgenic Rice to Drought Stress
Authors: Santoso Tri Joko , Apriana Aniversari Apriana , Sisharmini Atmitri Sisharmini , Trijatmiko Kurniawan Rudi
Published: October 2018

Drought stress is a major constrain which could influence rice productivity. Enhanced Response to ABA1 (ERA1) gene encoding a β-subunit farnesyltransferase enzyme plays a role to control sensitivity of the guard cells to abscisic acid (ABA), hence regulating drought stress response in plant species including rice. This study aimed to clone the OsERA1 gene into expression vector, introduce it into rice plant, and confirm the positive OsERA1-rice plants conferring drought tolerance. This study was initiated by isolation of the OsERA1 gene from rice cDNAs and cloned it to an expression vector cassette, pCAMBIA1301. The cassette harboring OsERA1 gene was introduced into rice plant cv. Nipponbare mediated by Agrobacterium tumefaciens strain LBA4404.
Putative transgenic lines were detected using PCR and Southern blot analyses to confirm the inserted transgene and the positive lines were assayed their tolerance to drought. The OsERA1 gene was successfully isolated and constructed into expression vector to generate pCAMBIA1301-OsERA1. Introduction of the gene into Nipponbare has produced nine putative transgenic rice lines, of which, six lines harbored OsERA1 gene. Southern blot analysis of sixteen T2 plants from two PCR-positive transgenic lines revealed
1–3 copies of transgene were integrated into rice genome of transgenic lines. Five transgenic lines of Nipponbare-OsERA1 showed better response to drought at vegetative phase compared to control in term of recovery ability. At generative phase, the five transgenic lines yielded less unfilled grains compared to control. Overall, the transgenic lines obtained from this study could be
potential candidates for developing rice varieties tolerant to drought.

 
Changes in Free Amino Acid Content in the Flesh and Peel of ‘Cavendish’ Banana Fruit as Related to Branched-chain Ester Production, Ripening, and Senescence
Authors: Alsmairat Nihad , Engelgau Philip , Beaudry Randolph
Published: October 2018

The concentrations of free amino acids in the peel and pulp of banana (Musa sp., AAA group, Cavendish subgroup, cv. Valery) fruit during ripening at 22 °C were measured. All 20 amino acids were quantified at seven distinct ripening stages as defined by measures of internal ethylene, O2, and CO2 concentrations, aroma volatile emissions, and peel color. Volatile production commenced 2 days after the peak in ethylene production and 1 day following the climacteric peak in internal CO2. The maximum rate of branched-chain ester synthesis occurred 2 to 3 days after its onset. Production of 2-methylpropyl and 3-methylbutyl esters was much higher in the pulp compared with the peel, confirming that the pulp, rather than the peel, is the primary site of banana aroma synthesis. Of the amino acids measured, only leucine, valine, and cysteine increased concomitantly with ester formation. This was observed in the pulp, but not in the peel. The data suggest the metabolic pathways for valine and leucine formation also support, respectively, the synthesis of 2-methylpropyl and 3-methylbutyl esters. It is not clear how leucine and valine can accumulate despite the fact that they act as feedback inhibitors of their respective synthetic pathways. There was a slight peak in the formation of several other amino acids in the pulp (e.g., alanine, arginine, asparagine, glutamine, and methionine) coinciding with the climacteric respiratory peak in CO2, but a similar pattern was not seen for the peel. These data are the first to demonstrate distinct differences in amino acid metabolism in the peel and pulp of banana related to their role in ripening and aroma biosynthesis.
Silencing of the SL-ZH13 Transcription Factor Gene Decreases the Salt Stress Tolerance of Tomato
Authors: Zhao Tingting , Hu Jingkang , Gao Yingmei , Wang Ziyu , Bao Yufang , Zhang Xiaochun , Yang Huanhuan , Zhang Dongye , Jiang Jingbin , Zhang He , Li Jingfu , Chen Qingshan , Xu Xiangyang
Published: October 2018

Zinc finger-homeodomains (ZF-HDs) are considered transcription factors that are involved in a variety of life activities in plants, but their function in regulating plant salt stress tolerance is unclear. The SL-ZH13 gene is significantly upregulated under salt stress treatment in tomato (Solanum lycopersicum) leaves, per our previous study. In this study, to further understand the role that the SL-ZH13 gene played in the response process of tomato plants under salt stress, the virus-induced gene silencing (VIGS) method was applied to down-regulate SL-ZH13 expression in tomato plants, and these plants were treated with salt stress to analyze the changes in salt tolerance. The silencing efficiency of SL-ZH13 was confirmed by quantitative real-time PCR analysis. SL-ZH13-silenced plants wilted faster and sooner than control plants under the same salt stress treatment condition, and the main stem bending angle of SL-ZH13-silenced plants was smaller than that of control plants. Physiological analysis showed that the activities of superoxide dismutase, peroxidase, and proline content in SL-ZH13-silenced plants were lower than those in control plants at 1.5 and 3 hours after salt stress treatment. The malondialdehyde content of SL-ZH13-silenced plants was higher than that in control plants at 1.5 and 3 hours after salt stress treatment; H2O2 and O2- accumulated much more in leaves of SL-ZH13-silenced plants than in leaves of control plants. These results suggested that silencing of the SL-ZH13 gene affected the response of tomato plants to salt stress and decreased the salt stress tolerance of tomato plants.
Influence of Inoculation with Bradyrhizobia and Nitrogen Rate on Yield and Estimated Economic Return of Virginia Market‐Type Peanut
Authors: Jordan David L. , Johnson P. Dewayne , Hare Andrew T. , Anco Dan , Chapin Jay , Thomas James , Monfort Scott , Balota Maria
Published: October 2018

Core Ideas

Bradyrhizobia inoculant increases peanut yield in new peanut fields and in fields with a recent history of peanut.

Applied nitrogen is less effective than inoculation with Bradyrhizobia in new peanut fields.

Return on investment from Bradyrhizobia inoculant occurs regardless of field history relative to peanut production.

Adequate nitrogen (N) fixation by peanut (Arachis hypogaea L.) is essential to optimize yield. In replicated trials in North Carolina, South Carolina, and Virginia from 1998–2017, commercially available in‐furrow liquid or granular inoculant increased yield from 3460 to 4660 lb/acre in new peanut fields (52 trials) and 4280 to 4450 lb/acre in fields with a previous history of peanut plantings within the past 4 years (43 trials). The increase in economic value from inoculation treatment ($8/acre) at a peanut price of $535/ton was $318/acre and $41/acre in fields with these respective histories. In a second experiment, replicated trials were conducted from 2007–2017 in fields without a history of peanut production or fields not rotated to peanut within at least the past 20 years. Economic return based on peanut prices described previously was determined to reflect cost of N applied as ammonium sulfate ($0.28/lb ammonium sulfate) as a single application 45 to 60 days after planting when canopy foliage began to express N deficiency. A linear or quadratic response to rates of 0, 60, 90, 120, and 150 lb N/acre was noted in five trials with no response observed in the remaining four trials. When these experiments were included with five other experiments where non‐inoculated and inoculated controls were compared with one rate only (120 lb N/acre), yield and economic return were greater for inoculated peanut compared with peanut receiving N or the non‐inoculated and non‐fertilized control. Nitrogen increased peanut yield and economic return compared with the non‐fertilized control. Results from these experiments underscore the value of inoculation with Bradyrhizobia at planting regardless of field history and the limitations of applied N to correct N deficiencies in peanut.
Genome‐Wide Association Study of Yield and Component Traits in Pacific Northwest Winter Wheat
Authors: Gizaw Shiferaw A. , Godoy Jayfred Gaham V. , Garland-Campbell Kimberly , Carter Arron H.
Published: October 2018

Grain yield and agronomic traits, key breeding goals for most crops, are under complex genetic control and subject to environmental interactions. Plant breeders require that the genetic architecture of agronomic traits be identified in locally relevant germplasm. Our goal was to conduct a genome‐wide association study to identify quantitative trait loci for eight agronomic traits in a diversity panel containing 402 Pacific Northwest winter wheat (Triticum aestivum L.) lines. Phenotypic evaluations of yield, yield components, phenology, and plant height were conducted under drought, rainfed, and irrigated conditions in 2012, 2013, and 2014. Linkage disequilibrium analysis, using 6492 single nucleotide polymorphism (SNP) markers from the 9K SNP array, determined that 70% of markers were in significant LD with other markers and formed 539 LD blocks with an average distance of 3.5 cM. Population structure analysis was conducted using 719 SNP tags that represent marker distribution. Three genetic subgroups were identified in the population, explaining 3 to 38% of the total phenotypic variation. A mixed linear model with 3653 SNP markers of known genetic position, the first two membership coefficients (Q = 2) of population structure and a compressed kinship (Kc = 192) was used in the association analysis. In this study, a total of 94 marker‐trait associations that were significant (false discovery rate < 0.05) were identified. Multiple trait associations for yield and component traits were identified on chromosomes 2B, 4B, 5A, 5B, 6A, and 7B. These findings highlight the possibility of using historical recombination in northern latitude winter wheat to identify genomic regions associated with desired agronomic traits.
La Sub familia Satyrinae (Lepidoptera: Nymphalidae) en la Estación Biológica Cocha Cashu, Parque Nacional del Manu - Madre de Dios
Authors: Moriano Melanie
Published: October 2018

La investigación se desarrolló en la estación biológica de Cocha Cashu, Manu – Madre de Dios, entre los meses de febrero y octubre del 2015, con la finalidad de evaluar la composición taxonómica de la subfamilia Satyrinae (Lepidoptera: Nymphalidae). La metodología utilizada fue de captura directa. Se colectaron 148 especímenes llegando a determinar 43 especies distribuidas en 4 tribus de la subfamilia Satyrinae, se utilizaron claves especializadas y la base de datos Butterflies of América. Los datos (diversidad en la temporada seca y húmeda) fueron analizados en el programa Past, determinándose que en la temporada seca la diversidad es mayor que la húmeda, con la dominancia de la especie Pierella lamia Sulzer, 1776.
Aprendizaje Basado en Proyectos con la plataforma Arduino en el desarrollo de las competencias de programación en la Universidad Privada del Norte-2017
Authors: Lévano Miguel
Published: October 2018

El objetivo de la investigación es evaluar la influencia del Aprendizaje Basado en Proyectos con la plataforma Arduino en el desarrollo de competencias de programación de los estudiantes de Ingeniería de Sistemas Computacionales.La muestra poblacional se conformó de estudiantes del sétimo ciclo del pregrado, de la carrera de Ingeniería de Sistemas Computacionales de la Universidad Privada del Norte (UPN). Se utilizó una metodología cuantitativa-cuasi experimental, utilizando encuesta y pruebas. Los resultados fueron: sí influye significativamente en el desarrollo de competencias de programación de los estudiantes del curso de robótica de la carrera de ingeniería de sistemas computacionales de la Universidad Privada del Norte. Esta influencia se hace evidente en las etapas del test del sistema robótico y del análisis del funcionamiento del sistema robótico.
La Relación de la Investigación Científica con la Motivación de Logro Académico en los Estudiantes de Postgrado de la Universidad Alas Peruanas
Authors: Carhuamaca Isbel
Published: October 2018

El presente artículo tiene carácter investigativo y cómo objetivo es determinar la relación que existe entre: La investigación científica y la motivación de logro académico. Este trabajo es de tipo descriptivo y correlacional, y corresponde a un diseño no experimental, de corte transversal, para ello se aplica un cuestionario que incluyó ítems de ambas variables, para ello se usa la técnica de la encuesta. El instrumento es validado a través el alfa de cronbach para medir la confiabilidad. Se está utilizando el análisis de relaciones utiliza las correlaciones simples entre los puntajes de las dimensiones y su respectiva variable , luego se calcula el coeficiente de correlación de Spearman para cada dimensión, por ser la adecuada para este tipo de variables (ordinales) con ello se construye el modelo estructurado ecuación modelo siendo los siguientesresultados: La Investigación Científica se relaciona directa y significativamente a un nivel de confianza del 95% con la motivación de logro académico según los Estudiantes de Postgrado Maestría en la Universidad Alas Peruanas Lima. Cuando Existe una buena motivación de logro académico se va a realizar una buena investigación científica por parte de los estudiantes.
Therapeutic potential of sulfathiazole silver for topical treatment of wound infection
Authors: Rodin A. V. , Privolnev V. V. , Barsukov A. N.
Published: October 2018

This article discusses the advantages and disadvantages of using silver compound-based preparations for topical treatment of wound infections. Comparative clinical studies showed the advantages of topical silver preparations that were used to treat the wound process. It also describes the advantages of sulfathiazole silver as a topical agent for the topical treatment of wound infections.
Treatment of lower extremity telangiectasias by thermocoagulation method using TS-3000 apparatus
Authors: Burleva E. P. , Ektova M. V. , Belentsov S. M. , Chukin S. A. , Makarov S. E. , Veselov B. A.
Published: October 2018

Objective: this paper aims at studying the efficacy of the thermocoagulation (TCG) method using TC-3000 apparatus for the treatment of lower extremity telangiectasias. Materials and methods. The TCG method has been used in 145 patients (223 cases) with telangiectasias (TA) and reticular veins (RV) of the lower extremities for 2 years. 17 patients (11.7%) had classes C1, 2 chronic venous diseases (CHV), and they underwent correction of pathological refluxes in the subcutaneous and perforating veins prior to TCG. Out of 128 patients with class C1 CHV, 25 people (19.5%) underwent microsclerotherapy (MST) in the past, just before the TCG procedure or in combination with it, MST was performed in 46 (35.9%). MST was performed for RV situated outside or within TA areas, and also was performed for TA from 0.6 to 1.0 mm in diameter. The TCG procedures were performed using TC-3000 (Belgium) apparatus, which operation is based on the impact of high-frequency electromagnetic field (4 MHz) on the dilated vessels in the skin. Needles made of nickel with a working diameter of 0.150 mm were used. Thermocoagulation was applied for the treatment of TA with a diameter of 0.3 mm to 0.6 mm. The results were evaluated within the following time-limits: 3 months (64 patients/97 limbs), 6 months (72/110), 12 months (70/107). Results of the treatment. The patients reported the results of the treatment as «no change and worse» in 73.4% of cases, pigmentation was detected in 73.2%, and residual TA in 81.4% of cases 3 months following the treatment. According to subjective assessment, the results were reported as «excellent» + «better» in 47.2%, pigmentation phenomena and residual TA were observed in 50.0% and in 50.9% of cases 6 months following the treatment. According to subjective assessment, the results were reported as «excellent» + «better» in 75.7%, pigmentation in 14.9%, residual TA in 13.1%, relapses TA in 14.0% 12 month following the treatment. Conclusion. 13.1% of patients with TA showed tolerance towards TCG. A positive effect included the absence of registered necrosis of the skin 3 months following the treatment, as well as atrophic and hypertrophic scars 12 months following the treatment.
Effects of chlorination, ultraviolet and ozone disinfection on the biotoxicity of triclosan
Authors: Chen Lei , Wang Zhipeng
Published: October 2018

The contamination of triclosan, which is a widely used antimicrobial agent, is of emerging concern for its potential toxicity to aquatic organisms and human beings. Chlorination, UV254 irradiation and ozonation are the main disinfection methods used in water treatment processes. Although studies have shown that triclosan could react with free chlorine and ozone, and undergo photolysis under UV irradiation, few of them focused on the effects of disinfection processes on the biotoxicity of triclosan. In the present study, the potential risk of triclosan in water before and after laboratory-scale disinfection processes, including chlorination, UV254 irradiation and ozonation, was evaluated by bioassay. The results showed that both acute toxicity and genetic toxicity of triclosan was increased by chlorination and UV254 disinfection but decreased by ozone disinfection. In other words, ozonation would be a preferential disinfection method for triclosan-containing surface waters. This finding will help us to choose an appropriate disinfection method for water treatment. Furthermore, it is proved that bioassay could be a feasible way for risk evaluation when concentrations of antibiotics in surface waters or drinking waters are very low.
Non-traditional trademarks: types and features of regulation
Authors: Pankova Mariia Nikolaevna
Published: October 2018

The article is devoted to the types and peculiarities of regulation of non-traditional trademarks. Non-traditional trademarks are considered to be: sound, volume, olfactory, taste and other designations. The most common non-traditional trademarks are sound marks. Non-traditional trademark must have a distinctive ability. There are different approaches to the criteria for the protection of non-traditional trademarks in the laws of foreign countries. The problem of the use of non-traditional trademarks is currently particularly relevant. But, despite the difficulties in their registration, every year there are new types of symbols.
Features of the style of the management as factor of specifics of corporate culture in education organization
Authors: Mikhailenko Anastasiia Aleksandrovna
Published: October 2018

Features of formation of corporate culture of school under the influence of such factor as style of the management – features of interaction of the head with collective are considered in article. Conditions of realization of powers of the management within work of school are revealed. The specifics of corporate culture in the educational organization – as the organizations of special type, social interaction and structure of relationship are shown.
Specificity of Russian corruption (based on sociological and social studies)
Authors: Lanskaya Irina Andreevna
Published: October 2018

One of the main problems of Russia is a high level of corruption in almost all spheres of life and development of society. In this study, various statistical and qualitative data characterizing the development of corruption in Russia are presented and analyzed.
Legal regulation of tourism sphere in Russian Federation
Authors: Kriazheva Elvira Gennadievna , Murzina Elena Aleksandrovna
Published: October 2018

The article analyzes the corpus of legal acts regulating the sphere of tourism. it is shown that the complex nature of tourism, its formation by many social relations, determines its regulation by the norms of several branches of law. It is specified that the state of regulation of the tourism industry depends on the current position of the branch dominant in the system of law.