bluuebunny/crossref_metadata_2025 huggingface dataset:
Medication-Related Osteonecrosis of The Jaw treatment Modalities, A review Article
Authors: Asadi Amir Ali
Published: August 2020

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents. Management of MRONJ has remained a controversial topic within the oral and maxillofacial surgery community.
Methods: Articles from 2010 to 2020 were selected. We determined that all review studies evaluated the effectiveness of various MRONJ therapies to resolve the condition were eligible for this study. We determined that all review studies evaluated the effectiveness of various MRONJ therapies to resolve the condition were eligible for this study.
Results: Antibiotic therapy such as penicillin-based antibiotics plus β-lactamase inhibitor or metronidazole could decrease disease progression and may prevent super infection of the bone. Surgery should be considered in all stages of MRONJ as it confirms the histology. fluorescence-guided surgery is helpful for MRONJ cases under Denosumab and it is recommended to use Low Level Laser and PDT as adjuvant treatment of MRONJ.
Conclusion: It seems that conservative treatment, minimally traumatic extraction technique, removal of bone edges and mucosal wound closure may prevent the occurrence of MRONJ
Study of Mortality Rate And Poisoning Status by Using Pesticides, Drugs, and Chemicals In Meshkinshahr, Ardabil Province
Authors: Moradi-asl Eslam , Nikookar Hassan , Danandehpor Peyman , Vakili Fazel , Asadyian Mehrdad , Adham Davoud
Published: August 2020

Background and Purpose: Poisoning with pesticides, drugs, and chemicals is one of the most important health problems in the world, causing a varying mortality rate in different regions. Easy access to a variety of drugs and poisons has caused some people to be hurt by using such things. The aim of this study was to evaluate the poisoning and mortality rate by using poisons, drugs, and chemicals in Meshkinshahr, a city in Ardabil Province.Materials   and  Methods: This descriptive and analytical cross-sectional study was conducted in Meshkinshahr Hospital from 2017 until the end of 2018. All information of people who were poisoned with pesticides, drugs, and chemicals was extracted from hospital case, and then was analyzed by SPSS 23.Results: Totally, 453 cases were referred to hospital with 173 (38.20 %) male and 280 (61.80 %) female. 73%  of the cases were poisoned by using  medications and  drugs , 18% by  using  other chemicals and 9% by poisons and pesticides. The mortality rate was 4%, with 70% due to exposure to pesticides and toxics, and 60% pertaining to deliberate suicide.Conclusion: According to the results of this study, most of the poisoning cases occurred as a result of using drugs; however, more than 70% of mortality was due to pesticides which indicated the toxicity of the pesticides. Also, the findings emphasized that the knowledge of target people is low.
Robust high-dimensional semiparametric regression using optimized differencing method applied to the vitamin B2 production data
Authors: Roozbeh Mahdi , Maanavi Monireh , Babaie-Kafaki Saman
Published: August 2020

Background and purpose: By evolving science, knowledge, and technology, we deal with high-dimensional data in which the number of predictors may considerably exceed the sample size. The main problems with high-dimensional data are the estimation of the coefficients and interpretation. For high-dimension problems, classical methods are not reliable because of a large number of predictor variables. In addition, classical methods are affected by the presence of outliers and collinearity.Methods: Nowadays, many real-world data sets carry structures of high-dimensional problems. To handle this problem, we used the least absolute shrinkage and selection operator (LASSO). Also, due to the flexibility and applicability of the semiparametric model in medical data, it can be used for modeling the genomic data. Motivated by these, here an improved robust approach in a high-dimensional data set was developed for the analysis of gene expression and prediction in the presence of outliers.Results: Among the common problems in regression analysis, there was the problem of outliers. In the regression concept, an outlier is a point that fails to follow the main linear pattern of the data. The ordinary least-squares estimator was found potentially sensitive to the outliers; this fact provided necessary motivations to investigate robust estimations. Generally, the robust regression is among the most popular problems in the statistics community. In the present study, the least trimmed squares (LTS) estimation was applied to overcome the outlier problem.Conclusions: We have proposed an optimization approach for semiparametric models to combat outliers in the data set. Especially, based on a penalization LASSO scheme, we have suggested a nonlinear integer programming problem as the semiparametric model which can be effectively solved by any evolutionary algorithm. We have also studied a real-world application related to the riboflavin production. The results showed that the proposed method was reasonably efficient in contrast to the LTS Method.
A study of barriers to adherence of antiretroviral treatment in prisoners living with HIV in Tehran, Iran
Authors: Seyedalinaghi Seyedahmad , Farhoudi Behnam , Harandi Hamid , Mahalleh Mehrdad , Dadras Omid , Alipour Amin , Alijani Mohsen
Published: August 2020

Background: People with chronic illnesses, such as HIV infection, face many barriers in the way of adherence to the treatment. In this study, the researchers attempted to investigate the barriers and facilitators of adherence to antiretroviral therapy (ART) among patients with HIV.Methods: Focus group discussion (FGD) was conducted with the primary objectives of investigating the barriers to ART adherence. Nine participants with HIV infection were recruited through a purposive sampling method at Great Tehran Prison.Results: In terms of the influencing factors of non-adherence; the drug side effects, especially with Efavirenz, Methadone and opioids effects resolution due to interaction with antiretroviral drugs, forgetfulness, fear of hangover due to the missed or delayed Methadone use, inappropriate nutrition and lack of access to food supplements and poverty were noted by majority of participants. In addition, there were some less, but still important factors of non-adherence among the patients, which were mentioned in the manuscript of the article.Conclusion: The medications side effects, inappropriate methadone prescription, stigma, lack of family support, and unfavorable prison conditions were found to be the potential barriers of adherence to HIV medication, whilst a strong and realistic patient-physician relationship, psychosocial and family support, and knowledge regarding the level of CD4 were amongst the possible facilitators for adherence to HIV medication in HIV-positive prisoners.
Inhalable wood dust: Risk assessment of Occupational exposure
Authors: Mohammadyan Mahmoud , Yazdani Charati Jamshid , Yousefinejad Raziye , Zare Rahman
Published: August 2020

Background and Purpose: Wood dust have been approved as a harmful and carcinogenic agent for humans. This study aimed to evaluate risk assessment of Workers' exposure to inhalable wood dust among 100 workers in 25 furniture manufacturing workshops in one of the northern cities in Iran.Materials and Methods: NIOSH0501 method was used to assess the occupational exposure to Inhalable wood dust and Semi-quantitative risk assessment method recommended by Singapore Department of Occupational Health was used to assess risk level of occupational exposure. Airborne particles were collected from the workers' breathing zone using calibrated personal sampler pump and a PVC filter with a 25 mm diameter, 5 µm pore size embedded inside an IOM Sampler.Results: The mean occupational exposure to inhalable wood dust among all exposed workers was found to be 22.3 ± 6.9 (Mean ± SD) mg.m-3. The risk level of workers' exposure to inhalable wood dust was also documented to be in medium level in all workshops. In addition, the researchers found that among environmental variables, the door area of workshops was the most effective predictor variable to predict variations of workers' exposure to inhalable wood dust (ADJ.R2=0.113, R2=0.122, p<0.001).Conclusion: Exposure to inhalable wood dust was several times higher than the OEL of Iran and TLV recommended by ACGIH. Since the risk level of workers' exposure to inhalable wood dust was in medium level, their health could be threatened by prolonged exposure. Therefore, technical-engineering and managerial controls seemed to be necessary.
A Systematic Review and Meta-Analysis of Randomized Controlled Trials Comparing the Safety of Dapagliflozin in Type 1 Diabetes Patients
Authors: Saha Sumanta , Saha Sujata
Published: August 2020

Background and Purpose: The dapagliflozin’s safety profile in insulin-treated adult type-1 diabetes mellites (T1DM) patients remains poorly explored. Therefore, this systematic review and meta-analysis compared the risk of all-cause side effects, study discontinuation of participants due to side effects, urinary tract infection (UTI), diabetic ketoacidosis, and hypoglycemia between dapagliflozin 10 mg and dapagliflozin 5 mg, dapagliflozin 10 mg and placebo, and dapagliflozin 5 mg and placebo.Materials and Methods: Parallel-arm randomized controlled trials juxtaposing the above outcomes between the afore-mentioned interventions were eligible for inclusion in this study and were searched in PubMed, Embase, and Scopus. Utilizing the Cochrane tool, the risk of bias was assessed in the recruited trials. Finally, by random-effect meta-analysis, each outcome was compared among the above interventions, and the risk ratio was estimated.Results: Four trials of varying length (1-52 weeks) sourcing data from almost 1760 participants from about 32 nations were reviewed. Overall, the trials had a low or unclear risk of bias, and only one was at a high risk of bias.  Compared to the placebo, the risk of side effects was higher in those treated with dapagliflozin 5 mg (RR=1.10; 95% CI=1.02-1.18; p=0.014; I2=0%). UTI risk was less with the 10mg dapagliflozin than its lower dose (RR=0.50; 95% CI=0.32-0.79; p-value=0.003; I2=0%). All the remaining comparisons were statistically not significantly different between the juxtaposed intervention pairs.Conclusion: In contrast to placebo, dapagliflozin 5mg increased the risk of overall adversities in insulin-treated type-1 diabetes, and dapagliflozin 10 mg had a reduced risk of UTI than its 5mg preparation.
Pathogen Infection Recovery Probability (PIRP) Versus Proinflammatory Anti-Pathogen Species (PIAPS) Levels: Modelling and Therapeutic Strategies
Authors: Sun Sam-Shajing
Published: August 2020

CoVID-19 pandemic due to SARS-CoV-2 virus has been spreading rapidly worldwide since late 2019, and it may become one of the largest pandemic events in modern human history if out of control.  It appears most of the CoVID-19 infection resulted deaths are mainly due to severe hypoxia from dysfunction of the lung, and that could be attributed to host’s immunodysfunctions particularly hyperinflammatory type disorders or allergic reaction.  In this brief review and study, a mathematical model is proposed to correlate the Pathogen Infection Recovery Probability (PIRP) versus Proinflammatory Anti-Pathogen Species (PIAPS) levels, where a maximum PIRP is expected when the PIAPS levels are equal to or around PIAPS equilibrium levels at the pathogen elimination or clearance onset.  Based on this model, rational or effective therapeutic strategies at right stages or timing, with right type of agents (immuno-stimulators or immuno-suppressors), and right dosages, could be designed and implemented that are expected to effectively achieve maximum PIRP or reduce the mortality.
Education in the Post-Pandemic Era: Indigenous Children and Youth
Authors: Cherubini Lorenzo
Published: August 2020

The COVID-19 pandemic crisis resulted in more than 100 countries legislating school closures in March 2020. In response, provincial ministries and their respective publicly funded school boards have implemented online learning platforms to avoid disruptions to student learning. For students already ostracized in public education, on-line learning may serve to further embed them in the proverbial margins. This editorial speaks to the urgency for educators at all levels to prepare for the potentially devastating outcomes on Indigenous student learning and progress in post-pandemic public schools and classrooms. The preparation for these realities has to be both immediate and retrospective given the complexities of these unique circumstances that have created interwoven layers of marginalization for Indigenous students.
Professional Identity, Professional Associations, and Recruitment: Perspectives of Current Doctoral Students and Recent Graduates of Rehabilitation Programs
Authors: Fleming Alison , Phillips Brian , Manninen-Luse Melissa , Irizarry Lesley O. , Hylton Terrie
Published: August 2020

This study was an exploratory investigation of the perceptions of current doctoral students and recent graduates from rehabilitation counseling and rehabilitation psychology programs on professional identity, professional associations, and recruitment. These three issues were selected based on the likelihood that students and recent graduates would have a different perspective than current leaders who are in the process of addressing these issues and would provide useful information. Participants' professional identities varied, but most felt that a unified identity for the discipline is important; a high percentage of participants held membership in at least one professional association; and most participants reported a willingness to recommend a master's or doctoral degree in rehabilitation counseling to a relative or friend.
Bir İnsansız Kara Aracı İçin Yüksek Verimli Fırçasız Doğru Akım Motoru Tasarımı
Authors: Kıvanç Ömer Cihan
Published: August 2020

İnsansız kara araçları (İKA) sahip oldukları farklı modüller sebebiyle araştırmacılara çeşitli çalışma alanları sunmaktadır. Bu modüller sensör teknolojileri, gömülü sistemler, haritalandırma ve konumlama, yörünge takibi, mekanik tasarım, elektrik motoru ve batarya teknolojileri gibi alanlardan oluşabilmektedir. Bu araştırma alanlarından elektrik motoru teknolojisinde her ne kadar bahsedilen diğer alanlara göre daha fazla limit tasarım değerlerine ulaşılmış olsa da insansız araçların sahip oldukları karmaşık ve kendine özgü kısıtlar sebebiyle farklı tasarım yaklaşımlarına ihtiyaç duyulmaktadır. Yapılan çalışmada çok yönlü hareket kabiliyetli, düşük sürtünmeli ve yüksek titreşimli bir İKA için özel bir dış rotorlu fırçasız doğru akım motoru (FDAM) tasarlanmıştır. Yapılan tasarımda düşük hız, yüksek moment ve yüksek verimde bir FDAM’u kısıtlı alan ve hacim koşulları göz önünde bulundurularak kolay imal edilebilir bir yapıda geliştirilmiştir. Çalışmada analitik çözümler ANSYS RMxprt, 2 ve 3 boyutlu analizler ise sonlu elemanlar yöntemine (SEY) dayanan ANSYS Maxwell ile yapılmıştır. Elde edilen sonuçlar, başlangıç motivasyonu ile tasarım çıktıları arasındaki uygunluğu göstermiş ve üretilebilir bir elektrik motoru geliştirilmiştir.
Przegląd badań dotyczących efektywności i produktywności polskiego szkolnictwa wyższego, prowadzonych za pomocą metody DEA i indeksu Malmquista
Authors: Brzezicki Łukasz
Published: August 2020

The article reviews the research on Polish higher education conducted for the DEA methods and the Malmquista index. The research was analysed due to various criteria: (1) including DEA models and Malmquist index, (2) areas of activity of higher education institutions, thereafter (3) types, groups and level of higher education analysis, (4) subsequently, the sources of data and variables accepted for the study. The results of the review show that research on Polish higher education is very little diversified, both in terms of the models used and the research area of higher education, with few exceptions.
Rejoinder to Wiśniewski on the Austrian welfare economics
Authors: Wysocki Igor , Megger Dawid
Published: August 2020

In the present short paper, we attempt to response the incisive criticisms directed at us by the eminent scholar Jakub Bożydar Wiśniewski. His rejoinder is nothing short of excellent, being concise and yet packed up with many insightful remarks, which gave us a sufficient reason to write this rejoinder in our turn. Our polemical note is structured as follows: we take Wiśniewski’s successive (as they appeared in his original rejoinder) critical points and reply them, while trying to treat our adversary’s position as charitably and seriously as possible and attempting to sharpen our standpoint even further.
Risk mitigation and the legal and ethical considerations for COVID-19 in a psychiatric inpatient setting
Authors: Blake Lucy , Pugh Ria , Skelton Luke , Baskind Eric , Harries Bethan , Butler Margaret , Sethi Faisil
Published: August 2020

This series of brief reports highlights the experience of a London psychiatric intensive care unit (PICU) that cared for patients with COVID-19 relatively early in the pandemic. The objective is to contribute to learning and consider the challenges for psychiatric intensive care services.
This article will discuss COVID-19-related risk prevention and mitigation strategies in a psychiatric inpatient setting, followed by an overview of the legal and ethical challenges, relating to risk prevention, mitigation and restrictive practice, in psychiatric inpatient care during the time
of the pandemic.
COVID-19, infection prevention and control within acute inpatient mental health facilities: a new challenge requiring a new approach
Authors: McLean Lisa , Forrester Louise
Published: August 2020

Mental Health inpatient units have a primary purpose of treating mental health problems, managing disturbance and promoting social contact and support networks. These factors can conflict with optimal infection prevention and control (IPC) measures.
 This commentary describes
an IPC perspective of the challenges in managing the effects of the COVID-19 pandemic that are specific to acute mental health settings. It points out the main areas for IPC and mental health practice development.
 The need for a new paradigm in the relationship between IPC and mental
health specialists is identified. Recent collaboration between mental health and IPC specialists in evaluating personal protective equipment (PPE) for use in restraint is outlined.
Segurança alimentar e nutricional
Authors: Souza Jordanna Peliser Fachinello de , Lima Romilda de Souza , Silochi Rose Mary Helena Quint , Panatto Emanuelle
Published: August 2020

Este trabalho objetiva discorrer sobre atividades realizadas em projeto de pesquisa e extensão realizado em parceria entre a Universidade Estadual do Oeste do Paraná, campus de Francisco Beltrão, Centro de Referência de Assistência Social – CRAS e Núcleo de Apoio à Saúde da Família. As ações fazem parte de objetivos de projeto aprovado em comitê de ética da instituição de ensino. O projeto atuou junto a mulheres atendidas pelo CRAS-norte, inseridas no Serviço de Proteção e Atendimento Integral à Família – PAIF. Dentre as atividades do PAIF, estão aquelas voltadas às ações comunitárias que envolvem palestras e outras atividades cujos temas de interesse são elencados pelo grupo. Saúde e educação alimentar foram temas escolhidos pelas participantes. Destacam-se, neste trabalho, as atividades relativas à segurança alimentar. São apresentados e discutidos os dados mais importantes obtidos pela aplicação da Escala Brasileira de Insegurança Alimentar – EBIA. O projeto foi um espaço de reflexão, de troca e [res] significação da alimentação, não só para as mulheres participantes do projeto, mas também para a equipe técnica, que se propôs à troca e à construção compartilhada do conhecimento. Durante o projeto foi possível identificar algumas mudanças nos hábitos alimentares das mulheres, no entanto, compreende-se que as mudanças acontecem de forma gradual e que cada pessoa leva um tempo diferente para sentir-se preparada para mudar.
Group A Rotavirus Gastroenteritis in Orphaned Leopardus Tigrinus and Leopardus Pardalis (CARNIVORA: FELIDAE) in the Eastern Amazon
Authors: Gabriel Áurea M. , Pereira Washington L.A. , Silva Klena S. , Souza Lorena , Nobre Akim F.S. , Mascarenhas Joana D’Arc , Linhares Alexandre da C.
Published: August 2020

Rotaviruses are highly infectious and typically transmitted by fecal-oral route via in the tropics and leading the cause of diarrheal deaths in children of developing countries, besides causing significant economic impacts like neonatal disease agents of domestic animals. This present report aims to present the clinical and diagnostic findings of two confirmed cases of rotavirus (RV) infection in orphaned Leopardus tigrinus (Schreber, 1775) and Leopardus pardalis (Linnaeus, 1758), the first register of the infection by group A rotavirus in these species. Both felids were rescued in the Pará State Amazon Brazil by the IBAMA (the Brazilian Institute of Environment and Renewable Natural Resources), and treated by veterinarians into intensive care ward in a public Environmental Park of Belém city. After the adaptation period to the quarantine, these animals showed non-specific symptoms of acute fulminant gastroenteritis. Rotavirus group A antigen was identified in blood and faecal samples of L. tigrinus analyzed by immunochromatography (ICG) and immunoassay methods (ELISA) at the Virology Laboratory of the Institute Evandro Chagas. The animals died within few days during the clinical exacerbation unresponsive to current treatment, its necropsies and histopathological analysis were performed in the Laboratory of Veterinary Pathology of the Federal Rural University of Amazonia (UFRA). Despite the compatible pathologic findings of rotavirus infection in both animals, the atypical hemorrhagic character was a curious finding, considering the presumed etiology.
Hyperbolic Rules in Genomes, the Harmonic Progression and Recurrence Sequences in Algebraic Biology
Authors: Petoukhov Sergey V.
Published: August 2020

The article is devoted to biological models using recurrence sequences, which are connected with the harmonic progression 1, 1/2, …, 1/n, and some cooperative properties of genomes. The harmonic progression is itself one of the recurrence sequences based on the harmonic mean. This progression appears in the hyperbolic rules of oligomer cooperative organization in eukaryotic and prokaryotic genomes. This allows thinking that the harmonic progression is also related to inherited physiological systems, which must be structurally consistent with the genetic coding system for their transmission to descendants and survival in evolution. The harmonic progression is one of historically known mathematical series, whose features were studied by Pythagoras, Leibniz, Newton, Euler, Fourier, Dirichlet, Riemann. It is widely used in many known algorithms and is closely related to some other important mathematical objects, for example, the function of the natural logarithm and harmonic numbers. Accordingly, the article describes the possibilities of using these interrelated mathematical objects to model biological structures, including logarithmic spirals and some other. Modeling inherited spiral configurations seems to be a particularly urgent task, since they are extremely common at all levels of organization of living bodies and, according to Goethe, are lines of life. The principle of a recurrence similarity, that is a special similarity of parts and transformations presented in recurrence sequences of numbers and matrix operators (the scale similarity and scale transformations are only particular cases of such similarity), is considered as one of the key principles of structural organization of living bodies.
The Use of Tailings as Raw Materials for Glass Making as an Alternative to Environmental Pollution: The Case of Osor, Catalonia, Spain
Authors: Alfonso Pura , Tomasa Oriol , Domenech Luis Miguel , Garcia-Valles Maite , Martinez Salvador , Roca Núria
Published: August 2020

Tailings from the Osor fluorite mines release large amounts of potentially toxic elements into the environment. This work is a proposal to remove these waste materials and use them as a raw material in the manufacture of glass. The chemical composition of the tailings was determined by X-ray fluorescence and the mineralogy by X-ray diffraction. Waste materials have SiO2, Al2O3 and CaO contents suitable for a glass production but Na has to be added, as NaCO3. Two glass formulations, with 80-90% of the residue and 10-20% Na2CO3, have been produced. The crystallization temperatures, obtained by differential thermal analysis, were 875 and 901 °C and the melting temperatures were 1220 and 1215 °C for the G80-20 and G90-10 glasses, respectively. The transition temperature of glass was of 637 and 628 °C. The crystalline phases formed in the thermal treatment to produce devitrification were nepheline, plagioclase and diopside in the G80-20 glass and plagioclase and akermanite-gehlenite in the G90-10 glass. The temperatures for the fixed viscosity points, the working temperatures and the coefficient of expansion were obtained. The chemical stability of the glass was tested, and results indicate that the potentially toxic elements of the tailings were incorporated into the glass structure.
Temporal Increase in D614G Mutation of SARS-CoV-2 in the Middle East and North Africa: Phylogenetic and Mutation Analysis Study
Authors: Sallam Malik , Ababneh Nidaa.A. , Dababseh Deema , Bakri Faris.G. , Mahafzah Azmi
Published: August 2020

Phylogeny construction can help to reveal evolutionary relatedness among molecular sequences. The spike (S) gene of SARS-CoV-2 is the subject of an immune selective pressure which increases the variability in such region. This study aimed to identify mutations in the S gene among SARS-CoV-2 sequences collected in the Middle East and North Africa (MENA), focusing on the D614G mutation, that has a presumed fitness advantage. Another aim was to analyze the S gene sequences phylogenetically. The SARS-CoV-2 S gene sequences collected in the MENA were retrieved from the GISAID public database, together with its metadata. Mutation analysis was conducted in Molecular Evolutionary Genetics Analysis software. Phylogenetic analysis was done using maximum likelihood (ML) and Bayesian methods. A total of 553 MENA sequences were analyzed and the most frequent S gene mutations included: D614G=435, Q677H=8, and V6F=5. A significant increase in the proportion of D614G was noticed from (63.0%) in February 2020, to (98.5%) in June 2020 (p<0.001). Two large phylogenetic clusters were identified via ML analysis, which showed an evidence of inter-country mixing of sequences, which dated back to February 8, 2020 and March 15, 2020 (median estimates). The mean evolutionary rate for SARS-CoV-2 was about 6.5 × 10-3 substitutions/site/year based on large clusters’ Bayesian analyses. The D614G mutation appeared to be taking over the COVID-19 infections in the MENA. Bayesian analysis suggested that SARS-CoV-2 might have been circulating in MENA earlier than previously reported.
A Negotiation Pricing Model for Innovation Services Based on the Multiobjective Genetic Algorithm
Authors: Zhou Yan , Li Yue , Zhang Yunxing
Published: August 2020

Service pricing is a bottleneck in the development of innovation services, as it is the issue of most concern between the suppliers and demanders. In this paper, a negotiation pricing model that is based on the multiobjective genetic algorithm is developed for innovation service pricing. Regarding the service pricing process as a multiobjective problem, the objective functions, which include the service price, service efficiency, and service quality, for suppliers and demanders are constructed. As the solution of a multiobjective problem is typically a series of alternatives, another negotiation process is necessary for determining the final decision. A learning strategy is adopted during the negotiation process to simulate reality. Finally, the model is implemented for an innovation service transaction, the objective of which is to identify the optimal price plan. The results demonstrate that the model can provide quantitative decision support for the pricing of an innovation service and ultimately yield a win-win result for both the supplier and demander of the innovation service. Furthermore, the influence of the parameters during the negotiation process is analyzed in detail. The effects of the learning strategy on accelerating the negotiation process, as well as the chosen of reasonable parameters are given.
Música e mídias: contribuições das teses e dissertações brasileiras Para a formação de professores
Authors: Natera Gislene , Girardello Gilka
Published: August 2020

O artigo apresenta e analisa um mapeamento das teses e dissertações sobre música e mídias realizadas entre 2000 e 2018 nos cursos brasileiros de Pós-Graduação em Educação e em Música. A partir de referências teóricas da educação musical e da mídia-educação, verificou-se que os temas mais frequentemente estudados são a influência das mídias na relação dos jovens com a música, e as maneiras como eles utilizam as tecnologias digitais, inclusive para constituir sua identidade musical. As pesquisas mostram que os professores precisam estar atentos aos novos desdobramentos culturais, e que os saberes musicais dos estudantes deveriam ser compartilhados e discutidos na escola. A análise do mapeamento valida a necessidade de a música e as mídias estarem presentes nos cursos de formação de professores, aproximando a escola das vivências midiático-musicais dos jovens, e favorecendo novas formas de aprendizagem musical e de reflexão cultural crítica e criadora para professores e estudantes.
Model-Based Analysis of Yo-yo Throwing Motion on Single-Link Manipulator
Authors: Miyakawa Hokuto ,   Tokyo Denki University 5 Senju Asahi-cho, Adachi-ku, Tokyo 120-8551, Japan, Nemoto Takuma , Iwase Masami
Published: August 2020

This paper presents a method for analyzing the throwing motion of a yo-yo based on an integrated model of a yo-yo and a manipulator. Our previous integrated model was developed by constraining a model of a white painted commercial yo-yo and a model of a plain single-link manipulator with certain constraining conditions placed between two models. However, for the yo-yo model, the collisions between the string and the axle of the yo-yo were not taken into account. To avoid this problem, we estimate some of the yo-yo parameters from the experiments, thereby preserving the functionality of the model. By applying the new integrated model with the identified parameters, we analyze the throwing motion of the yo-yo through numerical simulations. The results of which show the ranges of the release angle and the angular velocity of the joint of the manipulator during a successful throw. In conclusion, the proposed analysis method is effective in analyzing the throwing motion of a manipulator.
EFFECT OF AUTHENTICAL ASSESSMENT AND HIGH ORDER THINKING SKILL (HOTS) AGAINST TROUBLESHOOTING PHYSICAL PROBLEMS (An Experiment in The Students of SMA Negeri 2 Depok City)
Authors: Widyastuti Eni
Published: August 2020

Penelitian ini bertujuan untuk melihat pengaruh penilaian autentik dan high order thinking skill (HOTS) terhadap pemecahan masalah Fisika. Bentuk penilaian autentik mencakup kinerja dan portofolio. high order thinking skill (HOTS) mencakup high order thinking skill (HOTS) tinggi dan high order thinking skill (HOTS) rendah. Metode yang digunakan adalah treatment by level 2 x 2. Hipotesis penelitian diuji dengan menggunakan analisis varian (ANAVA) dua jalan. Hasil penelitian menyimpulkan bahwa: (1) hasil kemampuan pemecahan masalah Fisika kelompok siswa yang diberi bentuk penilaian autentik kinerja lebih tinggi dari hasil kemampuan pemecahan masalah Fisika kelompok siswa yang diberi bentuk penilaian autentik portofolio; (2) terdapat pengaruh interaksi yang signifikan antara bentuk penilaian autentik dan high order thinking skill (HOTS) terhadap hasil kemampuan pemecahan masalah Fisika; (3) khusus kelompok siswa yang memiliki high order thinking skill (HOTS) tinggi, hasil kemampuan pemecahan masalah Fisika kelompok siswa yang diberi bentuk penilaian autentik kinerja lebih tinggi dari hasil kemampuan pemecahan masalah Fisika kelompok siswa yang diberi bentuk penilaian autentik portofolio; (4) khusus kelompok siswa yang memiliki high order thinking skill (HOTS) rendah, hasil kemampuan pemecahan masalah Fisika kelompok siswa yang diberi bentuk penilaian autentik kinerja lebih rendah dari hasil kemampuan pemecahan masalah Fisika kelompok siswa yang diberi bentuk penilaian autentik portofolio.
Reconstruction of vocational high school physics instructional materials
Authors: Khoeriah Ira Herli , Abdullah Ade Gafar , Mulyanti Budi
Published: August 2020

Instructional materials for static electricity and dynamic electricity for Physics subjects in Vocational High Schools are not in accordance with the scope of the material contained in the Electronics Department: (1) The purpose of this study is to provide an overview of the teaching materials of static electricity and dynamic electricity in Physics in the Electronics Department; (2) Qualitative Content Analysis Method was used to explore the contents of seven book titles with different publishers and is strengthened through inter-views with Physics teachers in the Department of Electronics. In the process of analyzing the content of the contents of this textbook used Atlas.ti computer software; (3) The findings show that the content in the Vocational High School Physics books pub-lished by several publishers does not yet have specific conformity with the Department of Electronics; (4) conclusion. There are code relating to the content content, researchers only specify it into 39 code titles in the VHS Physics Textbook. from qualitative analysis. The level of compatibility of the content of the material with the 2013 Revised Curriculum was 42.86%, the availability of pictures was 75%, examples of questions from the equa-tions of each series were 85.71%, the suitability of the practicum with the Electrical Clump was 14.29%. content conformity with the Revised 2013 Curriculum and electro majors has a slightly low percentage of 42.86%. So in this study, the authors reconstruct VHS Physics teaching materials for the Electrical Department and also make VHS Physics teaching materials for the Electrical Clump.
Surgery Outcomes of Lamellar Macular Eyes with or without Lamellar Hole-Associated Epiretinal Proliferation: A Meta-Analysis
Authors: xu hanyue , Qin Ling , Zhang Yifan , Xiao Yinan , Zhang Ming
Published: August 2020

Background: Given the two different kinds of epiretinal membranes, this study aimed to compare both the structural and functional outcomes of lamellar macular holes with and without lamellar hole-associated epiretinal proliferation (LHEP) after surgery.Method: Publications up to July 2020 that compared the surgical outcomes of lamellar macular hole with and without LHEP were included. Forest plots were created by using a weighted summary of proportion meta-analysis. Fixed or random effects models were used on the basis of I2 heterogeneity estimates. Meanwhile, to evaluate the stability of the meta-analysis, a sensitivity analysis was carried out.Results: Eight pertinent publications that contained a total of 176 eyes without LHEP and 173 eyes with LHEP were included. They were all retrospective studies and had a follow-up of at least 6 months. In all studies, the preoperative best corrected visual acuity showed no significant differences between the two groups, and the visual acuity improved in both groups after surgery. The pooled result for the improved best corrected visual acuity was 0.18 (95% confidence interval (CI), 0.10 to 0.26; P< 0.01) between the with and without LHEP groups. The restored ellipsoid zone odds ratio was 0.80 (95% CI, 0.26 to 2.44; P= 0.69) for the group with LHEP compared to the group without LHEP.Conclusion: Patients without LHEP had better postoperative visual acuity than patients with LHEP. No significant difference in restored ellipsoid zone was found between the two groups.
Clinical characteristics and blood/serum bound prognostic biomarkers in advanced pancreatic cancer treated with gemcitabine and nab-paclitaxel
Authors: Blomstrand Hakon , Green Henrik , Fredriksson Mats , Gränsmark Emma , Björnsson Bergthor , Elander Nils
Published: August 2020

Background: In recent years treatment options for advanced pancreatic cancer has markedly improved, and a combination regimen of gemcitabine and nab-paclitaxel is now considered standard of care in Sweden and elsewhere. Nevertheless, a majority of patients do not respond to treatment. In order to guide the individual patient to the most beneficial therapeutic strategy, simple and easily available prognostic and predictive markers are needed. Methods: The potential prognostic value of a range of blood/serum parameters, patient-, and tumour characteristics was explored in a retrospective cohort of 75 patients treated with gemcitabine/nab-paclitaxel (Gem/NabP) for advanced pancreatic ductal adenocarcinoma (PDAC) in the South Eastern Region of Sweden. Primary outcome was overall survival while progression free survival was the key secondary outcome.Result: Univariable Cox regression analysis revealed that high baseline serum albumin (> 37 g/L) and older age (>65) were positive prognostic markers for OS, and in multivariable regression analysis both parameters were confirmed to be independent prognostic variables (HR 0.48, p=0.023 and HR=0.47, p=0.039,). Thrombocytopenia at any time during the treatment was an independent predictor for improved progression free survival (PFS) but not for OS (HR 0.49, p=0.029, 0.54, p=0.073), whereas thrombocytopenia developed under cycle 1 was neither related with OS nor PFS (HR 0.87, p=0.384, HR 1.04, p=0.771). Other parameters assessed (gender, tumour stage, ECOG performance status, myelosuppression, baseline serum CA19-9, and baseline serum bilirubin levels) were not significantly associated with survival. Conclusion: Serum albumin at baseline is a prognostic factor with palliative Gem/NabP in advanced PDAC, and should be further assessed as a tool for risk stratification. Older age was associated with improved survival, which encourages further studies on the use of Gem/NabP in the elderly.
Predictors of parental mediation in teenagers’ internet use: A cross-sectional study of female caregivers in Lahore, Pakistan
Authors: Iqbal Sarosh , Zakar Rubeena , Fischer Florian
Published: August 2020

Background: The internet has become the most widely used medium among teenagers, who spend much of their time online, which raises parental concerns. Notwithstanding teens’ increased internet use and exposure to online risks, little is yet known about parental internet mediation in local settings. The present research aimed to assess the various dimensions of parental mediation to regulate teens’ use of the internet, and their predictors. Methods: A cross-sectional survey was conducted in the district of Lahore, Pakistan, among mothers/female caregivers of teens (aged 13–19 years). Only women were interviewed because they are more frequently engaged as primary caregivers than fathers or male caregivers. Furthermore, only qualified and working mothers from the top two professions among women, i.e. academia and medicine, were interviewed. A stratified random sampling technique was adopted, and 347 mothers were interviewed using face-to-face interviews at 11 universities and 11 hospitals/medical colleges. Data was entered and analysed using descriptive, bivariate and multivariate logistic regression analyses.Results: The findings highlighted that more than 65% of respondents applied high active mediation of internet safety, around 60% used high active co-use mediation and more than 56% applied restrictive mediation. In addition, 36% of respondents monitored and 15.3% technically mediated to regulate their teens’ use of the internet. The results of the multivariate logistic regression revealed that the majority of respondents were more inclined to adopt active internet safety mediation if they had teens aged 16–19 years, with medium internet addiction, possessed good digital skills, felt confident about their teens’ coping appraisal to perform online protection, and considered their teens to have high self-esteem and resilience. Conclusions: This research found that parental internet mediation is a multi-faceted concept used to regulate teens’ online activity and enhance a resilient approach to reduce the risks associated with use of the internet. The researchers recommend developing parental guidelines, e-safety resource material, local support networks and community programmes to educate parents, teachers and teens in order to raise awareness and promote resilient pathways amongst teens.
Prevalence of reduced visual acuity among school-aged children and adolescents in 6 districts of Changsha city: a population-based survey
Authors: Liao Menglian , Cai Zehuai , Khan Muhammad Ahmad , Miao Wenjie , Lin Ding , Tang Qiongyan
Published: August 2020

Background: To calculate and evaluate the prevalence of reduced uncorrected distant visual acuity (UCDVA) in primary, middle and high schools in 6 districts of Changsha, Hunan, China.Methods: A population-based retrospective study was conducted in 239 schools in 6 districts of Changsha. After routine eye examination to rule out diseases that can affect refraction, 250,980 eligible students from primary, middle and high schools were enrolled in the survey. Then the uncorrected distant and near visual acuity of each eye were measured. Categories of schools, districts, grades, eye exercises and sports time were also documented and analyzed.Results: The overall prevalence of reduced UCDVA was 51.8% (95% confidence interval [CI]: 51.6%-52.0%) in 6 districts of Changsha. Results of individual districts were as follows: Furong district 59.9%(95% CI: 57.9%-61.8%), Tianxin district 62.3%(95% CI: 60.5%-64.0%), Wangcheng district 47.8%(95% CI: 46.8%-48.8%), Kaifu district 58.5%(95% CI: 58.0%-58.9%), Yuhua district 47.0%(95% CI: 46.7%-47.4%) and Yuelu district 52.6%(95% CI: 52.3%-52.9%). The proportion of normal VA is seen to decrease from primary grade 3. The proportion of mildly reduced UCDVA is higher in primary grade 1 and 2. The proportion of moderately reduced UCDVA remains similar during 12 grades. The proportion of severely reduced UCDVA increases with grades. Multivariate analysis shows that the prevalence of reduced UCDVA is higher in key schools (risk ratio [RR]= 1.47, 95% CI 1.44-1.50) than non-key schools. Conclusions: According to the existing data analysis results, the prevalence of reduced UCDVA among primary, middle and high school students in Changsha is very high. Some effective measures need to be taken to prevent it.
Health System Capacity for Post-Abortion Care in Java, Indonesia: A Signal Functions Analysis
Authors: Philbin Jesse , Soeharno Nugroho , Giorgio Margaret , Kurniawan Rico , Ingerick Meghan , Utomo Budi
Published: August 2020

Background: The quality of obstetric care has been identified as a contributing factor in Indonesia’s persistently high level of maternal mortality, and the country’s restrictive abortion laws merit special attention to the quality of post-abortion care (PAC). Due to unique health policies and guidelines, in Indonesia, uterine evacuation for PAC is typically administered only by Ob/Gyns practicing in hospitals. Methods: Using data from a survey of 657 hospitals and emergency obstetric-registered public health centers in Java, Indonesia’s most populous island, we applied a signal functions analysis to measure the health system’s capacity to offer PAC. We then used this framework to simulate the potential impact of the following hypothetical reforms on PAC capacity: allowing first-trimester uterine evacuation for PAC to take place at the primary care level, and allowing provision by clinicians other than Ob/Gyns. Finally, we calculated the proportion of PAC patients treated using four different uterine evacuation procedures. Results: Forty-six percent of hospitals in Java have the full set of services needed to provide PAC, and PAC capacity is concentrated at the highest-level referral hospitals: 86% of referral hospitals have the full set of services, staffing, and equipment compared to 53% of maternity hospitals and 34% of local hospitals. No health centers are adequately staffed or authorized to offer basic PAC services under Indonesia’s current guidelines. PAC capacity at all levels of the health system increases substantially in hypothetical scenarios under which authorization to perform first-trimester uterine evacuation for PAC is expanded to midwives and general physicians practicing in health centers. In 2018, 88% percent of PAC patients were treated using dilation and curettage (D&C). Conclusions: Offering first-trimester uterine evacuation for PAC in PONEDs and allowing clinicians other than Ob/Gyns to perform this procedure would greatly improve the capacity of Java’s health system to serve PAC patients. Increasing the use of vacuum aspiration and misoprostol for PAC-related uterine evacuation would lower the burden of treatment for patients and facilitate the task-shifting efforts needed to expand access to this life-saving service.
Determinants that Influence the Performance of Women Entrepreneurs’ in Micro and Small Enterprises in Ethiopia
Authors: Alene Endalew Terefe
Published: August 2020

Purpose: The purpose of this study was to explore determinants that influence women entrepreneurs’ performance in micro and small enterprises’ in Gondar city, Northwest Ethiopia and in turn contribute to entrepreneurship related literature mainly in developing countries.Design/methodology/approach: The study employed an explanatory research design with agreement of primary data collection via a cross-sectional survey questionnaire followed by quantitative research approach. The sample of this study was 180 women entrepreneurs and selected using random sampling technique. Findings: The findings of this study revealed that educational level, previous entrepreneurial experience, access to business training, access to finance, access to business information, government support, land ownership and tax are significant in explaining women entrepreneurs’ performance in one hand. On the other side, however, age, marital status, access to market and access to physical infrastructure are found to be insignificant variables in determining women entrepreneurs’ performance.Research limitations/implications: The study was used one time data for determinants like level of education, previous working experience, age and profitability of the enterprise. Thus, due to frequent change in such the variables, the study may not reflect the dynamics of the data, which would have a convinced influence on the conclusion. In addition, the research has only consisted of 180 samples. Moreover, such number may not represent the whole population of the entrepreneurs of Ethiopian MSEs. Future research, it is advisable to expand study factors, use interviews as a research tool and make comparison between women and men entrepreneurial performances.Practical implications: The paper might serve as an input for officials to consider such determinants and encourage an environment that increases women entrepreneurs’ performance. In addition, the study might help women entrepreneurs in addressing the factors affecting performance to take actions towards improving their performance and in turn contribute to job creation, wealth, innovation, and poverty alleviation.Originality/value: This study contributes to the literature on the determinants of women entrepreneurs’ performance in micro and small enterprises. Specifically, it tests the impact of educational level, age, marital status, previous entrepreneurial experience, access to business training, access to finance, access to business information, access to market, access to physical infrastructure, government support, land ownership and tax on the performance of women entrepreneurs’.