bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of the stress-strain state of the brake lever transmission of the 18-100 carriage model
Authors: Lovska Alyona , Ravlyuk Vasyl , Babenko Andrii
Published: May 2023

The object of research is the brake lever transmission of the 18-100 freight car carriage.
The investigated problem: the destruction of the elements of the triangle, which leads to the occurrence of failures during the car operation. As a result of such refusals, total losses for the railway infrastructure of Ukraine during freight transportation amount to hundreds of thousands of hryvnias.
The main scientific results: the strength of the brake lever transmission of the freight car carriage is investigated and the most loaded components of its structure are identified. It is proposed to improve the triangle string by making it from a round pipe filled with energy-absorbing material. Aluminum foam is used as an energy-absorbing material.
To justify the proposed solution, a calculation of the strength of the brake lever transmission is performed using the finite element method. The calculation results show that the maximum equivalent stresses that occur in the string do not exceed the allowable ones.
The peculiarity of the obtained results is that the proposed improvement of triangle elements can be applied not only at the stage of designing the mechanical brake system, that is, during the manufacture of car assemblies at car-building plants. It is advisable to apply the proposed solutions when carrying out depot or capital type repairs at car repair enterprises.
The field of practical use of the results is car-building and car-repair enterprises of railway transport of Ukraine.
Innovative technological product: the improvement of triangle elements will increase the efficiency of the braking systems of freight rolling stock, increase the speed of cars, reduce the time for the delivery of goods, reduce operating costs due to the failure of freight car units in operating conditions, and guarantee the level of safety of traffic on the railway. Also, the conducted research will contribute to the creation of developments in improving the reliability of the braking systems of modern rolling stock.
The scope of application of the innovative technological product: the fleet of freight cars of JSC "Ukrzaliznytsia", as well as its own industrial transport cars
Effect of faceting on olivine wetting properties
Authors: Huang Yongsheng , Nakatani Takayuki , Sawa Sando , Wu Guoji , Nakamura Michihiko , McCammon Catherine
Published: May 2023

Grain-scale pore geometry primarily controls the fluid distribution in rocks, affecting material transport and geophysical response. The dihedral angle (θ) in the olivine-fluid system is a key parameter determining pore fluid geometry in mantle wedges. In the system, curved and faceted olivine-fluid interfaces define θ, resulting in faceted-faceted (FF), faceted-curved (FC), and curved-curved (CC) angles. The effect of faceting on θ under various pressure and temperature (P-T) conditions and fluid compositions, however, has not been constrained, and mineralogical understanding remains unresolved. This study evaluated facet-bearing θ and their proportions in olivine-multicomponent aqueous fluid systems. Our results show that 1/3 of olivine-fluid θ are facet-bearing angles, regardless of the P-T conditions and fluid composition. Faceting produces larger dihedral angles than CC angles. The grain boundary plane (GBP) distribution reveals that the GBPs of faceted interfaces at triple junctions have low Miller index faces ({100}, {010}, and {101}). The misorientation angle/axis distributions of adjacent grain pairs are in accord with a theoretical distribution of random olivine aggregate. Moreover, the calculation of the FF angles for adjacent grain pairs with low Miller index GBPs reproduces measured angle values based on the olivine crystal habit. Therefore, our study suggests that the FF angle is strongly affected by olivine crystallography. The presence of faceting increases θ and a critical fluid fraction (φc) for percolation, lowering permeability. In the mantle wedge, where olivine crystallographic preferred orientation (CPO) is expected owing to corner flow, increasing the FF angle proportion with associated changes in fluid pore morphology will lead to permeability anisotropy, and controlling the direction of the fluid flow, and it will result in geophysical anomalies such as seismic wave attenuation and high electrical conductivity.
Rationale for the temperature regime of the foam separation cycle
Authors: Kovalenko Evgenii G.
Published: May 2023

The research objective is to determine the optimal temperature regimes for slurry preparation and foam separation of diamond-bearing kimberlites to ensure maximum diamond recovery under high selectivity of the process. Methods of research include the electron probe X-ray spectral analysis, IR spectrophotometry, and measurement of the contact angles of a collecting agent drop on diamonds or minerals. Technological studies were carried out on the setup for foam separation. Research results. It was shown that when the feedstock of the foam separation cycle is heated to a temperature of 80–85 °C the diamonds are effectively purified from hydrophilic coatings, which leads to the restoration of their natural floatability. Through contact angles measurement, the temperature range of 30–40 °C was determined in the feedstock reagent conditioning operation. It is shown that the maximum water repellence of diamonds is achieved in this temperature range without a significant increase in the kimberlite minerals water repellence. Laboratory experiments have shown that the best foam separation results are achieved when in the conditioning operation the feedstock with flotation reagents is maintained at a temperature of 30–38 °C. The flotation studies using F-5 bunker fuel oil as base collecting agent, as well as its compounds with diesel fraction and Machchobinsky oil, determined the optimal temperature of 14–24 °C directly in the process of foam separation. After data analysis, a temperature regime was proposed and tested, which includes the foam separation feedstock heating before the operation of slurry removal and conditioning with flotation reagents up to 85 °C and the subsequent use of accumulated heat in the operations of foam separation feedstock conditioning (30 °C) with reagents and the foam separation process itself (18 °C). The prospects of the technology. The test results of the selected temperature regime for the foam separation process on a test bench show the possibility of increasing the diamonds recovery into the concentrate by 2.3–4.5% when using applied and potential collecting agents, including F-5 bunker fuel oil and compounds based on it. The developed regime is recommended for commercial development in the foam separation cycle at Alrosa processing plants.
Rock pressure management during deep deposit development
Authors: Sentiabov Sergei
Published: May 2023

Relevance. The intensification of underground mining at the Gaisky underground mine is caused by the ever-increasing demand for raw materials and leads to mining depth growth. It therefore drives the need to formulate the problem of mining system structural elements stability. Data on the size and degree of fracturing of the rock mass disturbed layer on the outcrop (sheath) formed from natural cracks opening and drilling and blasting operations, made it possible to correct the stress distribution patterns on the contour and around the goaf. Research results established the dependence between the stress concentration and the structural weakening coefficient with distance from the outcrop. Research objective is to geomechanically substantiate rock pressure control methods and options for backfill mining method, improve safety and reduce geodynamic phenomena manifestation in the course of mining. Methods of research include full-scale experimental measurements of rock mass and ore stress state at accessible depths and horizons of the deposit. An integrated scientific research method was used which includes the analysis and theoretical generalization of the patterns of stress distribution in masses of extracted chamber reserves, mathematical modeling of the research results, and theoretical results comparison with the instrumental observations results. Results analysis. The paper presents the results of stress state formation in the ore in place, obtained through modern methods for mine structures stress-strain state calculation. Regularities in the rock mass stress state distribution were revealed. A set of active rock pressure control methods was formed on the example of the Gaisky underground mine. Findings. As compared to existing methods, rock pressure control is most effective through creating protective zones, artificial planes, using two panels in the lying and hanging sides tunneled along the strike of the ore body and forming sharp corners in the roof and bottoms, which will make it possible to move the maximum compressive stresses from technologically critical to less critical and more stable sections of the rock mass and concentrate the maximum compressive stresses on themselves, thereby unloading the workings of the bottom and the roof of future chambers in the protective zone. It is more rational to work out mining units with the I–II stage chambers according to existing schemes, and release the III stage chamber rock mass with double chambers and form diamond-shaped asymmetric interfloor pillars.
Visuals to Ideologies: Exploring the Linguistic Landscapes of Mindanao State University Marawi Campus
Authors: Abbas Juhaid H. , Samad Binnor M. Abdul , Imam Mohammad Hussein M. , Berowa Annie Mae C.
Published: May 2023

The research demonstrated the linguistic landscapes of the Mindanao State University Marawi Campus in the Southern Philippines, known as the “Melting Pot of the South”, where multilingualism, multiculturalism, and multimodality were quite situated. Linguistic Landscape (LL) encompassed and manifested the range of language use in society. Under the theoretical lens of linguistics, the research aimed to qualitatively and descriptively illustrate the linguistic tokens that marked the context of the school community. The needed data were photographed and collected inside the university premises and analyzed in terms of the number of languages used, language choice, and types of signs. The research reveals a sociolinguistic paradox: the multilingual realities of the school community and the prevalent exhibitions of monolingual English on its linguistic landscapes, which consequently seems to dishearten the status, propagation, promotion, and/or effectivity of multilingual policies and education in the Philippines. Furthermore, the research provides theoretical and practical contributions. Theoretically, it shows another lens of the notion of presumed language prestige and hierarchies. Furthermore, practically, it aids the deepening of knowledge and understanding of language use, and its implications, in public spaces. Finally, the research suggests revisiting and recalibrating the exhibition of multilingualism in the country by simply considering the status of language use in their environments, as they do not just reflect or manifest languages but also propagate and promote them.
Percepção de valor do suporte em redes de microfranquias: análise da teoria de Honeymoon
Authors: Ragazzi Isaac Victor , Alves Bezerra Adenilson , Lucas de Resende Melo Pedro
Published: May 2023

O modelo de microfranquias tem sido utilizado como opção de negócio por investidores que têm baixa capacidade financeira. Academicamente, há um prevalecimento de pesquisas sobre microfranquias relacionadas às questões socioeconômicas. Entretanto, este estudo tem como proposito preencher uma lacuna acadêmica latente ao se analisar aspectos de gerenciamento do suporte ao franqueado.  Assim, temos como objetivo verificar se há relação entre o tempo de franqueamento em redes de microfranquias e a percepção do microfranqueado em relação ao suporte que é prestador pelo franqueador. Os aspectos metodológicos envolveram a coleta de dados por meio de uma survey junto a 222 microfranqueados. Foram analisados como variável dependente, o tempo de franqueamento, e como variável independente o suporte ao franqueado, representado nos constructos (1) Treinamento; (2) Prospecção e Instalação; e (3) Assessoria Jurídica e Financeira. Utilizou-se o método de análise de regressão linear, que mostrou por meio dos resultados não haver relação entre o tempo de franqueamento e a percepção de valor do suporte pelo microfranqueado. Assim, as contribuições teóricas preenchem lacunas aos estudos de microfranquias, a teoria de honeymoon e a teoria de recursos.
Aplicação das ferramentas de gestão da qualidade para a otimização nos serviços e melhoria na gestão organizacional em uma academia de ginástica no município de Parauapebas-PA
Authors: Borba Marcelo Costa , Sena Ana Paula Souza , Freire Luan Sousa
Published: May 2023

Este manuscrito tem como objetivo analisar a aplicabilidade das ferramentas de gestão da qualidade em uma academia de ginástica no município de Parauapebas-PA, visando a otimização nos serviços e melhoria na gestão organizacional. Para isso, aplicou-se um diagrama de Ishikawa, onde foram levantadas possíveis causas que impactariam direta e/ou indiretamente no problema observado. Diante disso, buscou-se analisar por meio da aplicação de um questionário, a percepção do público externo com relação aos serviços prestados, a fim de confirmar quais possíveis causas, até então hipotéticas, implicariam de forma real no nível de satisfação dos clientes e, consequentemente, na evasão de alunos. Para investigação da causa raiz, adotou-se a ferramentas dos 5 Porquês, e, a partir dela, propôs-se um plano de ação. O resultado da pesquisa apresenta como fator principal que indica deficiências no serviço prestado estava ligado à categoria mão de obra, vinculados à pouca quantidade de instrutores que realizam atendimento aos alunos. Com o emprego das ferramentas que compõem este sistema, foram obtidas análises eficazes que atenderam as etapas de planejamento, controle e melhoria da qualidade nos serviços. Outros fatores avaliados como infraestrutura, qualidade do atendimento prestado pela equipe, quantidade de equipamentos disponibilizados no salão ou o estado de conservação destes equipamentos, possuem pouco impacto negativo na avaliação dos clientes da academia.
Difference Stackelberg Game Theoretic Model of Innovations Management in Universities
Authors:   Southern Federal University, Kalachev Vassily Yu. , Ougolnitsky Guennady A. ,   Southern Federal University, Usov Anatoly B. ,   Southern Federal University
Published: May 2023

We built a two-level difference game theoretic model "federal state universities" in open-loop strategies. The leading player (Principal) is the state or its representative bodies, the followers (agents) are competing a la Cournot universities. The agents assign their resources to the development of new online teaching courses which are considered as their innovative investments. An optimality principle from the point of view of agents is a set of Nash equilibria in their game in normal form, and from the point of view of the Principal it is a solution of the direct or inverse Stackelberg game "Principal-agents". The respective dynamic problems of conflict control are solved by means of the Pontryagin maximum principle and simulation modeling. The received results are analyzed, and the main conclusion is that two-level system of control of the innovative educational products promotion in the universities is necessary.
Inclusão de um surdo na pós-graduação
Authors: Barbosa Daniel Cícero dos Santos , Francisco Junior Wilmo Ernesto
Published: May 2023

Este artigo analisou o processo de inclusão de um estudante surdo em um curso de pós-graduação. Recorreu-se à narrativa autobiográfica para a investigação da trajetória educativa do primeiro autor, estudante-pesquisador surdo. Para a construção dos dados foram produzidos registros reflexivos em diários de campo acerca de quais obstáculos e aprendizagens foram vivenciados. A educação bilíngue foi um dos fatores principais para a trajetória até a pós-graduação. O acesso se fez possível por meio da política de cotas para pessoas com deficiência. No entanto, os desafios da permanência, já enfrentados no percurso escolar anterior, se estenderam ao Mestrado, com a particularidade do isolamento social provocado pela pandemia da COVID-19. O acesso aos materiais, às aulas e, principalmente, à socialização, tornou-se mais restrito. O contexto da pós-graduação tem se mostrado pouco inclusivo devido à ênfase na língua portuguesa, sendo necessário avançar nesse sentido para garantir maior acesso e permanência.
Tratamento endodôntico de pré-molares superiores com três raízes e três canais
Authors: Flávia Sens Fagundes TOMAZINHO  , Paola Cristine VALENÇA  , Tatiana Zaina BINDO  , Luís Fernando FARINIUK  , Flares BARATTO FILHO  , Fabrício SCAINI
Published: May 2023

Introdução: O conhecimento da anatomia interna dos dentes dehumanos é um dos fatores determinantes para o sucesso do tratamentoendodôntico. Algumas alterações anatômicas podem ser encontradasem maior ou menor freqüência durante o tratamento endodôntico,tornando-se importante o seu relato para um melhor entendimento dotema. Objetivo: Neste trabalho será abordado o tratamento propostopara pré-molares superiores com três raízes e três canais. Relato decaso: Avaliaram-se dois casos clínicos, um primeiro pré-molar direitoe um primeiro pré-molar esquerdo, além de um primeiro pré-molarsuperior extraído, apresentando 3 raízes com 3 canais. Conclusão: Apresença de três canais nos pré-molares superiores aumenta adificuldade de realizar o tratamento endodôntico nesse grupo dental.
Matrix Metalloproteinase-9, Neuron-specific Enolase, S100 B and Tau Protein
Levels in the Patients with Carbon monoxide Poisoning
Authors: Can Basri , Zengin Suat , Hakan Eren Şevki , Boğan Mustafa , Sabak Mustafa , Gülen Bedia , Ulusal Hasan , Mustafa Sunar Mehmet , Esat Karaduman Muhammet , Taysı Seyithan
Published: May 2023

Background:

S100B, NSE, MMP-9, and Tau protein levels increase in cases causing hypoxic cell damage. The diagnosis of the severity of carbon monoxide (CO) poisoning in the early period of these parameters was studied.

Material and Method:

COHb level measurement was made using a signal capture CO-pulse oximeter (Masimo's SET Rainbow, Masimo's Co, USA) at the first admission of the patients. Then, COHb levels were confirmed by arterial blood gas(ABG) analysis. The patients were divided into two groups as mild and moderate-severe, according to their Glasgow coma scores (GCS) [Mild (14–15); Moderate (9–13) or Severe (3–8)]. The control group was composed of 16 healthy and non-smoking volunteers.

Results:

The serum S100B protein and MMP-9 values at 0 hr of admission in the hospital and 3hr of treatment were not significantly different in the patient group as compared to the control group. Tau protein levels were significantly higher in the patient group at 0 and 3 hours (p> 0.05) as compared to healthy person.

Conclusion:

There was no relationship between CO poisoning and MMP-9 and S100B protein levels. NSE and Tau protein were significantly higher in the patient group than the control group. Tau protein may be more useful marker as compared to neuron-specific enolase.
The Prospect of Genomic, Transcriptomic, Epigenetic and Metabolomic
Biomarkers for The Personalized Prevention of Type 2 Diabetes and
Cardiovascular Diseases
Authors: Zeljkovic Aleksandra , Mihajlovic Marija , Vujcic Sanja , Guzonjic Azra , Munjas Jelena , Stefanovic Aleksandra , Kotur-Stevuljevic Jelena , Rizzo Manfredi , Bogavac-Stanojevic Natasa , Gagic Jelena , Kostadinovic Jelena , Vekic Jelena
Published: May 2023

Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular disease
(CVD), are a great health concern. The strategies aimed to increase awareness and prevention, in conjunction
with timely diagnosis and optimal management of these conditions, represent the main lines of
action to improve life expectancy and quality. In recent years, the introduction of innovative therapies
for the treatment of DM and CVD has provided new hope for high-risk patients. Yet, the implementation
of preventive measures in achieving cardiometabolic health is far from successful and requires further
improvement. The development of cardiometabolic disorders is a complex, multifactorial process
involving several metabolic pathways as well as genetic and environmental factors. Decreasing cumulative
exposure during the entire life course and timely recognition and targeting of potential riskenhancing
factors could pave the way toward more successful prevention of cardiometabolic disorders.
Nowadays, in the era of “omics” technologies, it is possible to identify novel biomarkers and therapeutic
targets, which offers the possibility to apply an individualized approach for each patient. This review
will discuss potential applications of genomic, transcriptomic, epigenetic and metabolomic biomarkers
for the personalized prevention of cardiometabolic diseases.
Green Approach Toward Triazole Forming Reactions for Developing
Anticancer Drugs
Authors: Rastogi Shiva K. , Ciliberto Veronica C. , Trevino Monica Z. , Campbell Brooke A. , Brittain William J.
Published: May 2023

Compounds containing triazole have many significant applications in the dye and ink industry, corrosion inhibitors, polymers, and pharmaceutical industries. These compounds possess many antimicrobial, antioxidant, anticancer, antiviral, anti-HIV, antitubercular, and anticancer ac-tivities. Several synthetic methods have been reported for reducing time, minimizing synthetic steps, and utilizing less hazardous and toxic solvents and reagents to improve the yield of triazoles and their analogues synthesis. Among the improvement in methods, green approaches towards tri-azole forming biologically active compounds, especially anticancer compounds, would be very important for pharmaceutical industries as well as global research community. In this article, we have reviewed the last five years of green chemistry approaches on click reaction between alkyl azide and alkynes to install 1,2,3-triazole moiety in natural products and synthetic drug-like mole-cules, such as in colchicine, flavanone cardanol, bisphosphonates, thiabendazoles, piperazine, prostanoid, flavonoid, quinoxalines, C-azanucleoside, dibenzylamine, and aryl-azotriazole. The cytotoxicity of triazole hybrid analogues was evaluated against a panel of cancer cell lines, includ-ing multidrug-resistant cell lines.
Synthesis, Molecular Modeling and Biological Evaluation of Novel
Trifluoromethyl Benzamides as Promising CETP Inhibitors
Authors: Abu Khalaf Reema , Abusaad Amani , Al-Nawaiseh Bara'a , Sabbah Dima , Albadawi Ghadeer
Published: May 2023

Background:

Hyperlipidemia is considered a major risk factor for the progress of atherosclerosis.

Objective:

Cholesteryl ester transfer protein (CETP) facilitates the relocation of cholesterol esters
from HDL to LDL. CETP inhibition produces higher HDL and lower LDL levels.

Methods:

Synthesis of nine benzylamino benzamides 8a-8f and 9a-9c was performed.

Results:

In vitro biological study displayed potential CETP inhibitory activity, where compound
9c had the best activity with an IC50 of 1.03 µM. Induced-fit docking demonstrated that 8a-8f and
9a-9c accommodated the CETP active site and hydrophobic interaction predominated ligand/
CETP complex formation.

Conclusion:

Pharmacophore mapping showed that this scaffold endorsed CETP inhibitors features and consequently elaborated the high CETP binding affinity.
Review of Carbon Nanotube Field Effect Transistor for Nanoscale Regime
Authors: Maqbool Mehwish , Sharma Vijay Kumar
Published: May 2023

Background:

The need for high performance, small size, low delay, low power consumption,
and long battery backup of portable systems is increasing with the advancement of
technology. Many features of portable systems can be improved using scaling methods. In the
scaling process, reducing the size of devices causes serious difficulties, including the short
channel effect (SCE) and leakage current, which degenerates the characteristics of the systems.

Objective:

In this review paper, a trending carbon nanotube field effect transistor (CNTFET)
technology is discussed in detail. CNTFET can replace the conventional metal oxide semiconductor
field effect transistor (MOSFET) technology to overcome the SCE problems in the nanoscale
regime and also meet the requirements of portable systems.

Methods:

The CNTFET is an extremely good nanoscale technology due to its one-dimension
band structure, high transconductance, high electron mobility, superior control over channel
formation, and better threshold voltage. This technology is used to construct high-performance
and low-power circuits by replacing the MOSFET technology. CNTFET in comparison to
MOSFET takes the carbon nanotube (CNT) as a channel region.

Results:

The value of threshold voltage in CNTFET changes with the diameter of CNT. The
threshold voltage of the devices controls many parameters at the circuit-level design. Hence, the
detailed operation and the characteristics of CNTFET devices are presented in this review paper.
The existing CNTFET-based ternary full adder (TFA) circuits are also described in this review
paper for the performance evaluation of different parameters.

Conclusion:

CNTFET technology is the possible solution for the SCE in the nanoscale regime
and is capable to design efficient logic circuits. The circuits using the CNTFET technology can
provide better performance and various advantages, including fast speed, small area, and low
power consumption, in comparison to the MOSFET circuits. Thus, CNTFET technology is the
best choice for circuit designs at the nanoscale.
Exosomal-microRNAs Improve Islet Cell Survival and Function In Islet
Transplantation
Authors: Minhua Qiu , Bingzheng Feng , Zhiran Xu , Yingying Zhang , Yuwei Yang , Ting Zhang , Jibing Chen , Hongjun Gao
Published: May 2023

Exosomal-microRNAs (Exo-miRNAs) are key regulators of islet cell function, including insulin
expression, processing, and secretion. Exo-miRNAs have a significant impact on the outcomes of islet
transplantation as biomarkers for evaluating islet cell function and survival. Furthermore, they have been
linked to vascular remodeling and immune regulation following islet transplantation. Mesenchymal stem
cell-derived exosomes have been shown in preliminary studies to improve islet cell viability and function
when injected or transplanted into mice. Overall, Exo-miRNAs have emerged as novel agents for improving
islet transplantation success rates. The role of islet-derived Exo-miRNAs and mesenchymal stem
cells-derived Exo-miRNAs as biomarkers and immunomodulators in islet regeneration, as well as their
role in improving islet cell viability and function in islet transplantation, are discussed in this review.
Novel Arcyriaflavin-A Derivatives as PIM Kinase Inhibitors for Treating Cancer
Authors: De Surya K.
Published: May 2023

The present application reports a series of novel Arcyriaflavin-A derivatives as PIM kinase inhibitors for the
effective treatment of cancer. The application also describes the synthesis of compounds in detail, use, pharmaceutical
composition, pharmaceutically acceptable salts, and treatment.
An Integrated Approach for Analysis of Electronic Health Records Using
Blockchain and Deep Learning
Authors: Singhal Pooja , Gupta Shelly , Deepak  , Singh Jagendra
Published: May 2023

Blockchain is used to assess health records digitally, preserving the security and immutability of the records. The goal of this study is to make it easier for patients to access their medical records and to send them alert messages about important dates for their check-ups, healthy diet, and appointments. To achieve the above-mentioned objective, an integrated approach using Blockchain and Deep learning is initiated. The first approach is Hyperledger Fabric in Blockchain, i.e., private Blockchain, for storing the data in the medically documented ledger, which can be shared among hospitals as well as Health organizations. The second approach is incorporated with a deep learning algorithm. With the help of algorithms, we can analyse the ledger, after which an alert i.e. consultation, health diet, medication, etc., will be sent to the patient’s registered mobile device. The proposed work uses nine features from the dataset; the features are identification number, age, person gender, disease, weight, consultation date, medication, diagnosis, and diet specification. The study is conducted with several features to give accurate results. The integrated model used in this suggested piece of work automates the patient's alert system for a variety of activities. In terms of precision, recall, and F1 score, testing data demonstrate that the LSTM performs better than the other models. By working together with the calendar software on Android mobile devices, alert systems can be improved in the future.
Probiotics and Health: A Review
Authors: Tomar Priti , Sharma Shikha , Dangi Neha
Published: May 2023

Humans serve as hosts for various species of microorganisms that contribute to the maintenance
of human health. The beneficial bacteria residing in our bodies are referred to as probiotics.
Besides improving the immune system, probiotics are also capable of warding off various diseases. In
recent decades, probiotic microorganisms have emerged as a significant factor in human well-being.
Popularly referred to as "health-friendly microorganisms," they influence health in myriad ways by
boosting the immune system, combating intestinal irritation, improving the balance of the gut microbiome,
lowering blood pressure, relieving postmenopausal symptoms, and reducing traveler’s diarrhea.
The ability of probiotics to compete for the adhesion sites of pathogenic microbes makes them
an effective treatment against various intestinal pathogens. Recent studies also advocate their use in
the treatment of skin and oral diseases. In addition, the modulation of gut flora by probiotics is being
discussed as a possible new solution for treating tension and depression. Ultimately, a cost-effective
approach is imperative to improve and maintain fitness in the present competitive environment. This
review aims to evaluate the potential benefits of probiotic microorganisms in various disorders, such
as gastrointestinal disorders, UTIs, acne, anticancer properties, gut-brain connections, and their possible
mode of action.
A New Lighthouse on the Horizon: The Emergence of ASEAN-China Comprehensive Strategic Partnership
Authors:   University of Padjadjaran, Josafat Manullang Abel , Agung Prio Wicaksono Raden ,   University of Padjadjaran
Published: May 2023

Recently, China has made a comprehensive strategic partnership (CSP) with ASEAN that would open up more opportunities for the two parties. However, some view it as another success on China’s part as it now has gained influence over ASEAN. But such a view that downplays ASEAN into a mere instrument for China’s plan in the region would not provide a proper view. Through the use of qualitative research methods over data gathered through the internet and documents, the article seeks to shed light over the forthcoming points. First, the article lays out the things that the CSP brings both for ASEAN-China relations and ASEAN’s standing in the Indo-Pacific. Here, the partnership paves the way for stronger ties between ASEAN and China, not to mention the impact it has towards ASEAN’s growing centrality. The article then proceeds with the challenges that may arise following the emergence of the partnership. On this matter, the inconsistent cohesion within ASEAN along with the ongoing competition for influence in the region can be viewed as some of the challenges. After that, a discussion over the many opportunities for enhancement is also presented. Here, the partnership would allow ASEAN to maintain its growing centrality in its many channels, one of which is its ASEAN way that guides the interactions and norm settings in the region. With all that laid out, it can be understood that the creation of the partnership does not make ASEAN lose its luster, rather it accentuates its centrality in the Indo-Pacific.
Ekspansi Fast Fashion melalui Jaringan Produksi Global terhadap Penyerapan Tenaga Kerja di Jawa Barat
Authors:   University of Padjadjaran, Fadillah Tirta K Yusuf , Sudirman Arfin ,   University of Padjadjaran, Silvya Sari Deasy ,   University of Padjadjaran
Published: May 2023

Penelitian ini akan membahas mengenai ekspansi kapital yang bergerak lewat Jaringan Produksi Global yang ditenggarai oleh pergerakan budaya Fast Fashion terhadap penyerapan tenaga kerja di Jawa Barat. Penelitian ini menggunakan konsep Ekspansi Kapital dengan menggunakan logika dasar Kapitalisme serta konsep Jaringan Produksi Global. Tulisan ini terbatas pada dampak ekonomi dari jaringan produksi global tekstil dan fast fashion terhadap penyerapan tenaga kerja di Jawa Barat sehingga masing masing daerah baik kota maupun kabupaten memiliki produktivitas ekonomi serta mampu membantu Indonesia dalam meningkatkan investasi luar negeri, berkompetisi dengan negara berkembang dan memiliki ekspor industri padat karya terbesar di kawasan maupun global. Tulisan ini menggunakan metode penelitian kualitatif deskriptif dengan sumber penelitian primer maupun sekunder yang berasal dari hasil observasi ke institusi pemerintah, internet based research, serta studi kepustakaan. Penelitian ini menjelaskan dan percaya bahwa dengan adanya jaringan produksi global di sektor fast fashion mampu menurunkan angka pengangguran dan meningkatkan produktivitas ekonomi di Jawa Barat serta meningkatkan nilai ekspor tekstil Indonesia.
Tracking the Money: The Case of 1MDB Scandal
Authors:   University of Brawijaya, Shafira Chairunnisa Rizqi , Shabrina Lana , Julia Julia , Allaam Zaidan ,   University of Brawijaya,   University of Brawijaya,   University of Brawijaya
Published: May 2023

The UN estimated US$800 billion to US$2 trillion is laundered every year. But unfortunately, about 90% of this amount remains undetectable to this day. This money laundering activity performs money laundering services on behalf of other people as their core business and is usually carried out in a different country. In this case, of course, money laundering becomes a complex transnational crime. This crime is widespread throughout the world, including in Malaysia. Malaysia is a country with an upper-middle-income economy that is very open to exposure to various threats of money laundering. According to Money Laundering Risk in 2022 data by the Basel Institute of Governance, Malaysia ranks 54th out of 128 countries with a score of 5.33 where a score of 10 indicates the highest risk. Even though Malaysia has the instruments to detect criminal acts, unfortunately, cooperation and political will are still considered lacking, making it difficult to eradicate it. This paper was compiled to identify money laundering in transnational crimes, and also to analyze the model of condition and model of operation in the 1MDB corruption case.
Anti-Inflammatory Effects of Ripe Areca Nut Ethyl Acetate Fraction in Wistar Rats with Knee Joints Osteoarthritis
Authors: Yuda Daffa Akrama , Rahman Ave Olivia , Kasmadi Fathnur Sani , Humaryanto Humaryanto
Published: May 2023

Osteoarthritis (OA) is the most common form of arthritis. Meloxicam are one of NSAIDs commonly used that have many side effects. Areca nut (Areca catechu L), which contains flavonoids, can provide anti-inflammatory effects. This study aimed to determine the potential anti-inflammatory effect of ethyl acetate fraction from ripe areca nut in OA rat model. Twenty five of adults, male Rattus novergicus strain Wistar were induced to OA with Monosodium Iodoacetate (MIA), then divided into five groups that each group were given ethyl acetate fraction of ripe areca nut doses of 15mg/kgBW, 30mg/kgBW, and 60mg/kgBW, meloxicam 1.35mg/kgBW and aquadest as negative control for 14 days. Diameter of the knee joint is measured by digital metric kaliper to assess joint edema. The Histopathological examination with Haematoxyllin-Eosin stain to assess degree of inflammation on synovial. Among the areca groups, dose 30mg/kgBW had knee joint diameter reduced better and lower synovitis score. In conclusion, ethyl acetate fraction of the ripe areca nut group has anti inflammation effect in OA model but not dose-dependent.
Correlation between Atherogenic Index of Plasma and Various Domains of Cognitive Function in Type 2 Diabetes Mellitus Patients
Authors: Fitri Fasihah Irfani , Simanjuntak Pahala
Published: May 2023

Cognitive impairment in patients with Type 2 Diabetes Mellitus (T2DM) is related to the lack of blood supply to the brain. Previous studies showed that the atherogenic index of plasma (AIP) is a predictor of vascular abnormalities, but studies investigating its association with cognitive functions in T2DM patients younger than 60 years remain limited. This study aimed to determine the correlation between AIP and various domains of cognitive function in T2DM patients. This study was a cross-sectional study involving 75 T2DM patients selected using a consecutive sampling technique at Haji Adam Malik General Hospital Medan from July 2021 to January 2022. Cognitive function was examined using the Visual Cognitive Assessment Test Indonesian Version (VCAT-INA) on several cognition domains. The AIP value of each patient was measured and categorized into high (AIP>0.21), intermediate (AIP between >0.11 and ≤0.21), or low (≤0.11). The mean triglyceride level was 176±108.3mg/dl, the HDL-C level was 38.3±12.1mg/dl, and the mean AIP value was 0.191±0.25. The mean score of the VCAT-INA was 21.7±2.3, which was lower than normal. The AIP value showed significant negative correlation with global cognition (r=0.432, p<0.001) and various cognitive domains, namely memory (r=-0.375, p=0.001), attention (r=-0.383, p=0.001), executive function (r=-0.051, p=0.663), visuospatial (r=-0.306, p=0.008), and language (r=-0.352, p=0.002). In short, there is a significant correlation between AIP value and domains of cognitive function, such as memory, attention, visuospatial, and language domains, but not with executive domains.
Antibiotic Use Evaluation in ICU/HCU of Muhammadiyah University General Hospital Malang using DDD and Gyssens Methods
Authors: Rachmawati Hidajah , Muktamiroh Muktamiroh , Hasmono Didik , Kusumaningtyas Atika Putri , Yunita Sendi Lia , Yusetyani Lilik
Published: May 2023

Infection is a condition caused by the propagation of harmful microorganisms with or without clinical symptoms. Improper use of antibiotics can lead to antibiotic resistance. The Ministry of Health of the Republic of Indonesia recommended a quantitative evaluation of the use of antibiotics using the Defined Daily Dose (DDD) method and a qualitative evaluation using the Gyssens method. This study evaluated antibiotics usage using DDD and Gyssens methods in ICU/HCU of the Muhammadiyah University General Hospital Malang. Employing retrospective observational method, data were collected from patient medical records hospitalized during January-December 2020. Results of the DDD quantitative analysis showed that the most widely used antibiotic was Ceftriaxone with a 35.79 DDD/100 patient-days. The Gyssenss qualitative analysis showed that the category VI (incomplete patient's medical record data) was 3%, category IVa (antibiotic use is more effective) (2%), category IIIb (duration of antibiotic use is too short) (3%), category IIb (antibiotic use is not at the right interval) (3%).
Een universiteit voor Antwerpen. Van aspiratie naar proeftuin voor Belgisch onderwijsbeleid (1954-1971)
Authors: Coussement Alexia
Published: May 2023

Throughout Belgium’s first century of existence, there have been repeated calls to establish a university in the city of Antwerp. It took until the late 1950s to gain the necessary support for this cause. In the process, different views on the concrete realization of this project emerged. Because of the many voices within this debate, which also broadened to a national scale, more rational formulas had to make way for a compromising solution. Instead of creating one university, three incomplete university institutions were established between 1965 and 1971: RUCA (a state institution), UFSIA (a catholic, private institution), and UIA (a pluralistic foundation). Belgian policymakers considered the cooperation between these differing institutions a unique experiment which had the potential to end the rigid pilarization of the Belgian academic landscape.
Waarom de dichter lacht: humor in de poëzie van PA. de Génestet en François HaverSchmidt
Authors: Manu Anthony
Published: May 2023

This article has two objectives. Firstly, it aims to show that the existing models for textual humour studies must be adapted in order to be used for the analysis of poetic texts, specifically for poems in which the use of rhetorical devices plays a central role. Secondly, it seeks to demonstrate that an analysis based on insights from textual humour studies can enrich a reading of humorous poetry. By combining and expanding contemporary incongruity- resolution theories of lingual humour, I introduce a methodology, which I then use to analyse the role of humour in the poems “Niet aardig” (“Not witty”) by P.A. de Génestet and “Immortelle LXXXIV” by François HaverSchmidt. I argue that the humorous effect is caused by a shift between rhetorical schemata and that it evokes a thought process which leads to a relatively sober handling of idealistic desires.
Onpersoonlijke datief-nominatiefwerkwoorden in het hedendaagse Duits: definitie, inventaris en semantische classificatie
Authors: Somers Joren
Published: May 2023

Several studies have drawn attention to the fact that subjecthood is not necessarily associated with nominative case-marking (Andrews 1976, Þráinsson 1979, Zaenen, Maling & Þráinsson 1985, Sigurðsson 1989, inter alia).1 This article seeks to contribute to the study of non-canonically case marked subjects by zooming in on nominative-dative verbs in Present-Day with a subject-like oblique argument (henceforth: impersonal dative-nominative verbs). The aim of this article is twofold. First, I present an exhaustive list of all German impersonal dative-nominative verbs, and secondly, I aim to classify them according to the semantic typology suggested by Barðdal et al. (2016). The results show that impersonal dative-nominative verbs are far more numerous than hitherto assumed, and that their semantic distribution gravitates towards meanings pertaining to emotions, cognitive processes, and contexts of gain and benefit.
Het interesseert me geen ene je-weet-wel – Minimaliserende strategieën in het hedendaagse Nederlandse Nederlands
Authors: Van den Heede Margot , Lauwers Peter
Published: May 2023

This paper focuses on minimizing strategies in present-day Netherlandic Dutch. The minimizing construction under investigation consists of (1) an element of negation (geen); (2) a predicate and (3) a minimizer, a noun that denotes a small quantity and that is used to reinforce sentential negation (e.g. geen woord begrijpen ‘to understand not a word’). First, we situate the minimizing construction in relation to other, pragmatic minimizing strategies. Then, we provide a semantic typology of the minimizers in our dataset. Moreover, we give an overview of the different strategies that are available to extend the slot of the minimizer, such as analogical and context-based extensions. This shows the productivity (in terms of lexical scope) of the minimizing construction.
Affectieve ideeënpoëzie: Over kennis in de gedichten van Rozalie Hirs en Anne Carson
Authors: Van Praet Helena
Published: May 2023

The Dutch Rozalie Hirs and Canadian Anne Carson are two contemporary poets whose poetry centres on a discursive or conceptual questioning of ideas. Yet little scholarly attention has been paid to this epistemological aspect of their work. This article therefore addresses how their poetry deals with knowledge and which strategies are used to this end. First, the relationship between knowledge and poetry is explored. Building on examples from Carson’s Glass and God (1998) and Hirs’s oneindige zin (2021), amongst other works, the article then examines what kind of engagement with knowledge such forms of poetry engender and in what ways. Finally, the comparative analysis suggests that an erotic epistemology, focused on a desire for knowledge, lies at the heart of Hirs’s and Carson’s poetry. To conclude, the notion of an affective poetry of ideas is proposed.
Interpersonal meaning breadth variation in simultaneous interpreting English – bahasa Indonesia dienic texts: A contrastive-translational mood grammar analysis
Authors: Christiani Intan
Published: May 2023

This study presents a contrastive-translational MOOD grammar analysis of the realization of interpersonal meaning in Joyce Meyer’s English sermon text and Jose Carol’s Bahasa Indonesia interpreted text. Interpersonal meaning in the framework of Systemic Functional Linguistics (SFL), the model of Translational Semiotic Communication (TSC) and the model of text type and language function are the theoretical foundations of this study. This study used a descriptive qualitative-quantitative approach, involving the analysis of MOOD and Modality of the data which were translationally related semantic units grammatically expressed by MOOD clause units. The analysis reveals that the texts in this study can be classified as dienic texts with Declaratives and Imperatives as the prominent clauses, while Modality elements realized in T1 were generally realized in T2 in the same types. Declaratives and Imperatives respectively serve the informative and operative function of the texts, and the Modality elements which are mostly of a high degree and expressed explicitly give values to these functions.
Improving reading comprehension through the development of critical thinking of students at madrasah aliyah
Authors: Mustopa Arif Zaenal , Sugirin Sugirin
Published: May 2023

This research aims to develop the reading comprehension skills in English written texts of Grade XI students of Madrasah Aliyah Al-Ikhlash Cicalengka, Bandung through the development of critical thinking in teaching process. This research was collaborative classroom action research. The subjects were the 11th grade students of Madrasah Aliyah Al-Ikhlash Cicalengka, Bandung. The data were collected through pretest and posttest, observation, field notes, and interviews. The students were introduced with the concept of critical thinking starting with the concept of position, agreement, disagreement, and argument as well as the categorization of the opinion and fact in the text. Finally the students were asked to do some tasks and give their opinion related to the position of the writer and their background knowledge. The result showed that there was an improvement in teaching processes. In the first cycle, the students’ involvement in classroom activity was improved. There were about 70% of the students who actively involved in the process and it increased in the second cycle. In expressing opinion, the students could actively express their opinion related to the text being discussed both in written and orally.  The improvement also occurred in students’ reading comprehension skills score. The result of paired t-test showed that there was significant different in comparison of pretest and both posttests 1 and 2. The result showed that the significant value of 0.000 was smaller than the significant level of 0.05 or 5%. This means that the improvement was significant. The result proved that improving reading comprehension skills could be achieved by developing critical thinking in teaching reading process.