bluuebunny/crossref_metadata_2025 huggingface dataset:
LONG-TERM OUTCOMES AFTER CORRECTION OF LONG CORONARY LESIONS USING BIODEGRADABLE VASCULAR SCAFFOLDS
Authors:   Republican Scientific and Practical Centre «Cardiology», N. Strygo , V. Stelmashok ,   Republican Scientific and Practical Centre «Cardiology», O. Polonetsky ,   Republican Scientific and Practical Centre «Cardiology»
Published: September 2022

Materials and methods. Over the period of 2013 to 2018, endovascular correction of long (more than 25 mm) coronary artery lesions was performed on 80 patients in RSPC “Cardiology”, Minsk. Randomly the patients were divided into 2 groups: experimental group (EG) (n = 40) – endovascular correction with bioresorbable everolimus-eluting vascular scaffold Absorb BVS, and control group (CG) (n = 40) – endovascular correction with everolimus-eluting metallic stent Xience V/ Xience Pro. During further observations we estimated the development of death outcomes (from any reasons and from heart diseases), cases of acute myocardial infarction, incidence of revascularization due to target lesion patency failure, as well as a combined endpoint (all death cases + cases of acute myocardial infarction+ revascularization due to target lesion patency failure). The information about the presence or absence of negative outcomes was collected during the observation via a telephone contact with the patient or their relatives. Results. In the mean long-term observational period of 86.5 months (interquartile range from 77.0 to 93.0 months) after percutaneous intervention (PCI) total death cases were registered in 7.5% cases for the experimental group and in 5% cases for the control group (CG) (p = 1.00). The combined endpoint (death + myocardial infarction + target lesion revascularization) was registered in 17.5% cases for EG and in 15% cases for CG (p = 1.00). Kaplan-Meier analysis did not reveal statistical signif icance between the study groups (p = 0.78). Conclusion. Long lesion correction with biodegradable vascular scaffolds shows similar long-term clinical results in comparison with everolimus-eluting stents. The combined endpoint risk (all death cases + myocardial infarction + revascularization due to target lesion failure) statistically did not differ in long-term period between both groups.
A CLINICAL CASE OF INTRACARDIAC THROMBOSIS ASSOCIATED WITH SARS-COV-2 INFECTION
Authors:   Belarusian State Medical University, A. Pleshko , T. Statkevich ,   Belarusian State Medical University, E. Petrova ,   Belarusian State Medical University,   Republican Scientific and Practical Centre “Cardiology”, N. Mitkovskaya ,   Belarusian State Medical University,   Republican Scientific and Practical Centre “Cardiology”
Published: September 2022

The damage to humanity and global healthcare done by the COVID-19 pandemic is hard to overestimate. According to the World Health Organization (WHO), there were more than 500 million confirmed cases of SARS-CoV-2 infection, more than 6 million of which were fatal. The high incidence of arterial thrombosis and venous thromboembolic complications despite the ongoing antithrombotic therapy, often leading to death in patients with new coronavirus infection SARS-CoV-2, indicates the need for profound study of the pathogenetic aspects of procoagulant status and a more rational personalized approach in prophylactic measures in this category of patients. Special interest is the development of thrombotic complications in COVID-19 convalescents. This article presents a clinical case of a 43-year-old man with no cardiovascular history who suffered viral myocarditis with thrombus formation in the heart cavities, thrombosis of deep veins of the lower extremities and consequent pulmonary thromboembolism, all of which developed within a month after coronavirus infection. In the article authors discuss the leading pathophysiological mechanisms that potentially could propagate the development of thrombosis and thromboembolic complications in patients with COVID-19.
TRANSCATHETER PULMONARY VALVE IMLANTATION AFTER SURGICAL CORRECTION OF RIGHT VENTRICULAR OUTFLOW TRACT: THE EXPERIENCE OF ONE CENTER
Authors:   Republican Centre of Pediatric Surgery, P. Charnahlaz , V. Kadochkin ,   Republican Centre of Pediatric Surgery, Y. Linnik ,   Republican Centre of Pediatric Surgery, K.  ,   Republican Centre of Pediatric Surgery
Published: September 2022

Transcatheter pulmonary valve implantation (TPVI) is a relatively new method of treating patients with right ventricular outflow tract (RVOT) dysfunction after surgical treatment of congenital heart defects. Since its introduction in 2000 by Bonhoeffer, more than ten thousand of such procedures have been performed worldwide. Currently two types of valves are available in the Republic of Belarus: Melody TPVMedtronic and Edwards Sapien. TPVI is safe and effective in the majority of patients with RVOT dysfunction and in some selected patients with patched RVOT. The low complication rate and the reduced number of open-chest re-interventions over a patient’s lifetime are among the main advantages of the procedure. The article presents a literature review, and summarizes the experience and results of TPVI performed on 24 patients in the Republican Centre of Pediatric Surgery.
Ozone depletion in the Arctic and Antarctic stratosphere induced by wildfire smoke
Authors: Ansmann Albert , Ohneiser Kevin , Chudnovsky Alexandra , Knopf Daniel A. , Eloranta Edwin W. , Villanueva Diego , Seifert Patric , Radenz Martin , Barja Boris , Zamorano Félix , Jimenez Cristofer , Engelmann Ronny , Baars Holger , Griesche Hannes , Hofer Julian , Althausen Dietrich , Wandinger Ulla
Published: September 2022

Abstract. A record-breaking stratospheric ozone loss was observed over the Arctic and Antarctica in 2020. Strong ozone depletion occurred over Antarctica in 2021 as well. The ozone holes developed in smoke-polluted air. In this article, the impact of Siberian and Australian wildfire smoke (dominated by organic aerosol) on the extraordinarily strong ozone reduction is discussed. The study is based on aerosol lidar observations in the North Pole region (October 2019–May 2020) and over Punta Arenas in southern Chile at 53.2∘ S (January 2020–November 2021) as well as on respective NDACC (Network for the Detection of Atmospheric Composition Change) ozone profile observations in the Arctic (Ny-Ålesund) and Antarctica (Neumayer and South Pole stations) in 2020 and 2021. We present a conceptual approach on how the smoke may have influenced the formation of polar stratospheric clouds (PSCs), which are of key importance in the ozone-depleting processes.
The main results are as follows: (a) the direct impact of wildfire smoke below the PSC height range (at 10–12 km) on ozone reduction seems to be similar to well-known volcanic sulfate aerosol effects. At heights of 10–12 km, smoke particle surface area (SA) concentrations of 5–7 µm2 cm−3 (Antarctica, spring 2021) and 6–10 µm2 cm−3 (Arctic, spring 2020) were correlated with an ozone reduction in terms of ozone partial pressure of 0.4–1.2 mPa (about 30 % further ozone reduction over Antarctica) and of 2–3.5 mPa (Arctic, 20 %–30 % reduction with respect to the long-term springtime mean).
(b) Within the PSC height range, we found indications that smoke was able to slightly increase the PSC particle number and surface area concentration. In particular, a smoke-related additional ozone loss of 1–2 mPa (10 %–20 % contribution to the total ozone loss over Antarctica) was observed in the 14–23 km PSC height range in September–October 2020 and 2021. Smoke particle number concentrations ranged from 10 to 100 cm−3 and were about a factor of 10 (in 2020) and 5 (in 2021) above the stratospheric aerosol background level. Satellite observations indicated an additional mean column ozone loss (deviation from the long-term mean) of 26–30 Dobson units (9 %–10 %, September 2020, 2021) and 52–57 Dobson units (17 %–20 %, October 2020, 2021) in the smoke-polluted latitudinal Antarctic belt from 70–80∘ S.
Diazotrophy as a key driver of the response of marine net primary productivity to climate change
Authors: Bopp Laurent , Aumont Olivier , Kwiatkowski Lester , Clerc Corentin , Dupont Léonard , Ethé Christian , Gorgues Thomas , Séférian Roland , Tagliabue Alessandro
Published: September 2022

Abstract. The impact of anthropogenic climate change on marine net primary
production (NPP) is a reason for concern because changing NPP will have
widespread consequences for marine ecosystems and their associated services.
Projections by the current generation of Earth system models have suggested
decreases in global NPP in response to future climate change, albeit with
very large uncertainties. Here, we make use of two versions of the Institut
Pierre-Simon Laplace Climate Model (IPSL-CM) that simulate divergent NPP
responses to similar high-emission scenarios in the 21st century and
identify nitrogen fixation as the main driver of these divergent NPP
responses. Differences in the way N fixation is parameterised in the marine
biogeochemical component PISCES (Pelagic Interactions Scheme for Carbon and Ecosystem Studies) of the IPSL-CM versions lead to N-fixation rates
that are either stable or double over the course of the 21st century,
resulting in decreasing or increasing global NPP, respectively. An
evaluation of these two model versions does not help constrain future NPP
projection uncertainties. However, the use of a more comprehensive version
of PISCES, with variable nitrogen-to-phosphorus ratios as well as a revised
parameterisation of the temperature sensitivity of N fixation, suggests only
moderate changes in globally averaged N fixation in the 21st century. This
leads to decreasing global NPP, in line with the model-mean changes of a
recent multi-model intercomparison. Lastly, despite contrasting trends in
NPP, all our model versions simulate similar and significant reductions in
planktonic biomass. This suggests that projected plankton biomass may be a
more robust indicator than NPP of the potential impact of anthropogenic
climate change on marine ecosystems across models.
Carbon Cycle Extremes Accelerate Weakening of the Land Carbon Sink in the Late 21st Century
Authors: Sharma Bharat , Kumar Jitendra , Ganguly Auroop R. , Hoffman Forrest M.
Published: September 2022

Abstract. Rising atmospheric CO2 concentrations enhance vegetation growth through increased carbon fertilization and water-use efficiency. Terrestrial vegetation takes up more than one-quarter of global anthropogenic carbon emissions, and uptake is modulated by regional climate. Increasing surface temperature could lead to enhanced evaporation, reduced soil moisture availability, and more frequent droughts and heat waves. The spatiotemporal co-occurrence of such effects further drives extreme anomalies in vegetation productivity and net land carbon storage. However, the impacts of climate change on extremes in net biospheric production (NBP) over longer time periods are unknown. Here we show that due to climate warming, about 88 % of global regions will experience a larger magnitude of negative NBP extremes than positive NBP extremes toward the end of 2100, which accelerate the weakening of the land carbon sink. Our analysis indicates the frequency of negative extremes associated with declines in biome productivity was larger than positive extremes, especially in the tropics. While the overall impact of warming at high latitudes is expected to increase plant productivity and carbon uptake, high-temperature anomalies increasingly induce negative NBP TCEs toward the end of the 21st century. We found soil moisture anomalies as the most dominant individual driver of NBP extremes and the compound effect of hot, dry, and fire caused extremes at more than 50 % of the total grid cells. The larger proportion of negative NBP extremes raises a concern about whether the Earth is capable of increasing vegetation production with growing human population and rising demand for plant material for food, fiber, fuel, and building materials. The increasing proportion of negative NBP extremes highlights the consequences of not only reduction in total carbon uptake capacity but also of conversion of land to a carbon source.
Seismic amplitude response to internal heterogeneity of mass-transport deposits
Authors: Ford Jonathan , Camerlenghi Angelo , Zolezzi Francesca , Calarco Marilena
Published: September 2022

Abstract. Compared to unfailed sediments, mass-transport deposits are often characterised by a low-amplitude response in single-channel seismic reflection images. This ‘acoustic transparency’ amplitude signature is widely used to delineate mass-transport deposits and is conventionally interpreted as a lack of coherent internal reflectivity due to a loss of preserved internal structure caused by mass-transport processes. In this study we examine the variation in the single-channel seismic response with changing heterogeneity using synthetic 2-D elastic seismic modelling. We model the internal structure of mass-transport deposits as a two-component random medium, using the lateral correlation length (ax) as a proxy for the degree of internal deformation, whilst maintaining approximately constant internal reflectivity with increasing deformation. For a controlled single-source synthetic model a reduction in observed amplitude with reduced ax is consistently observed across a range of vertical correlation lengths (az). For typical AUV sub-bottom profiler acquisition parameters, in a simulated mass-transport deposit with realistic elastic and geostatistical properties, we find that when ax ≈ 1 m, recorded seismic amplitudes are, on average, reduced by ∼ 15 % relative to unfailed sediments (ax ≫ 103 m). We also observe that deformation significantly larger than core-scale (ax > 0.1 m) can generate a significant amplitude decrease. These synthetic modelling results should discourage interpretation of the internal structure of mass-transport deposits based on seismic amplitudes alone, as ‘acoustically transparent’ mass-transport deposits may still preserve coherent, metre-scale internal structure. In addition, the minimum scale of heterogeneity required to produce a significant reduction in seismic amplitudes is likely much larger than the diameter of sediment cores, meaning that ‘acoustically transparent’ mass-transport deposits may still appear well-stratified and undeformed at core-scale.
Multitemporal glacier inventory revealing four decades of glacier changes in the Ladakh region
Authors: Soheb Mohd , Ramanathan Alagappan , Bhardwaj Anshuman , Coleman Millie , Rea Brice R. , Spagnolo Matteo , Singh Shaktiman , Sam Lydia
Published: September 2022

Abstract. Multi-temporal inventories of glacierised regions provide an
improved understanding of water resource availability. In this study, we
present a Landsat-based multi-temporal inventory of glaciers in four Upper
Indus sub-basins and three internal drainage basins in the Ladakh region for
the years 1977, 1994, 2009 and 2019. The study records data on 2257 glaciers
(of individual size >0.5 km2) covering an area of
∼7923±106 km2 which is equivalent to
∼30 % of the total glacier population and ∼89 % of the total glacierised area of the region. Glacier area ranged
between 0.5±0.02 and 862±16 km2, while glacier length
ranged between 0.4±0.02 and 73±0.54 km. Shayok Basin has the
largest glacierised area and glacier population, while Tsokar has the least.
Results show that the highest concentration of glaciers is found in the
higher elevation zones, between 5000 and 6000 m a.s.l., with most of the
glaciers facing towards the NW–NE quadrant. The error assessment shows that
the uncertainty, based on the buffer-based approach, ranges between 2.6 % and
5.1 % for glacier area, and 1.5 % and 2.6 % for glacier length with a mean
uncertainty of 3.2 % and 1.8 %, respectively. This multitemporal inventory
is in good agreement with previous studies undertaken in parts of the Ladakh
region. The new glacier database for the Ladakh region will be valuable for
policy-making bodies, and future glaciological and hydrological studies. The
data can be viewed and downloaded from
PANGAEA, https://doi.org/10.1594/PANGAEA.940994 (Soheb et al., 2022).
Drainage reorganization induces deviations in the scaling between valley width and drainage area
Authors: Harel Elhanan , Goren Liran , Crouvi Onn , Ginat Hanan , Shelef Eitan
Published: September 2022

Abstract. The width of valleys and channels affects the hydrology, ecology,
and geomorphic functionality of drainage networks. In many studies, the
width of valleys and/or channels (W) is estimated as a power-law function of
the drainage area (A), W=kcAd. However, in fluvial systems
that experience drainage reorganization, abrupt changes in drainage area
distribution can result in valley or channel widths that are disproportional
to their drainage areas. Such disproportionality may be more distinguished
in valleys than in channels due to a longer adjustment timescale for
valleys. Therefore, the valley width–area scaling in reorganized drainages
is expected to deviate from that of drainages that did not experience
reorganization. To explore the effect of reorganization on valley width–drainage area
scaling, we studied 12 valley sections in the Negev desert, Israel,
categorized into undisturbed, beheaded, and reversed valleys. We found that
the values of the drainage area exponents, d, are lower in the beheaded
valleys relative to undisturbed valleys but remain positive. Reversed
valleys, in contrast, are characterized by negative d exponents, indicating
valley narrowing with increasing drainage area. In the reversed category, we
also explored the independent effect of channel slope (S) through the
equation W=kbAbSc, which yielded
negative and overall similar values for b and c. A detailed study in one reversed valley section shows that the valley
narrows downstream, whereas the channel widens, suggesting that, as
hypothesized, the channel width adjusts faster to post-reorganization
drainage area distribution. The adjusted narrow channel dictates the width
of formative flows in the reversed valley, which contrasts with the meaningfully
wider formative flows of the beheaded valley across the divide. This
difference results in a step change in the unit stream power between the
reversed and beheaded channels, potentially leading to a “width feedback”
that promotes ongoing divide migration and reorganization. Our findings demonstrate that valley width–area scaling is a potential tool
for identifying landscapes influenced by drainage reorganization. Accounting
for reorganization-specific scaling can improve estimations of erosion rate
distributions in reorganized landscapes.
Patterns and rates of soil movement and shallow failures across several small watersheds on the Seward Peninsula, Alaska
Authors: Del Vecchio Joanmarie , Lathrop Emma , Dann Julian B. , Andresen Christian G. , Collins Adam D. , Fratkin Michael M. , Zwieback Simon , Glade Rachel C. , Rowland Joel C.
Published: September 2022

Abstract. Thawing permafrost can alter topography, ecosystems, and sediment and carbon fluxes, but predicting landscape evolution of permafrost-influenced watersheds in response to warming and/or hydrological changes remains an unsolved challenge. Sediment flux and slope instability in sloping saturated soils have been commonly predicted from topographic metrics (e.g., slope, drainage area). In addition to topographic factors, cohesion imparted by soil and vegetation and melting ground ice may also control spatial trends in slope stability but the distribution of ground ice is poorly constrained and hard to predict. To address whether slope stability and surface displacements follow topographic-based predictions, we document recent drivers of permafrost sediment flux present on a landscape in western Alaska that include creep, solifluction, gullying, and catastrophic hillslope failures ranging in size from a few meters to tens of meters and we find evidence for rapid and substantial landscape change on an annual timescale. We quantify the timing and rate of surface movements using a multi-pronged, multi-scalar dataset including aerial surveys, interannual GPS surveys, Synthetic Aperture Radar Interferometry (InSAR), and climate data. Despite clear visual evidence of downslope soil transport of solifluction lobes, we find that the interannual downslope surface displacement of these features does not outpace downslope displacement of soil in topographically smooth areas (downslope movement means: 7 cm yr-1 for lobes over two years vs 10 cm yr-1 in smooth landscape positions over one year). Annual displacements do not appear related to slope, drainage area or solar radiation but are likely related to soil thickness, and volumetric sediment fluxes are high compared to comparable temperate landscapes. Timeseries of InSAR displacements show accelerated movement in late summer, associated with intense rainfall and/or deep thaw. While mapped slope failures do cluster at slope-area thresholds, a simple slope stability model driven with hydraulic conductivities representative of throughflow in mineral and organic soil drastically over-predicts the occurrence of slope failures. This mismatch implies permafrost hillslopes have unaccounted-for cohesion and/or throughflow pathways, perhaps modulated by vegetation, which stabilize slopes against high rainfall. Our results highlight the breadth and complexity of soil transport processes in Arctic landscapes and demonstrate the utility of using a range of synergistic data collection methods to observe multiple scales of landscape change, which can aid in predicting periglacial landscape evolution.
Soil-vegetation-water interactions controlling solute flow and transport in volcanic ash soils of the high Andes
Authors: Páez-Bimos Sebastián , Molina Armando , Calispa Marlon , Delmelle Pierre , Lahuatte Braulio , Villacís Marcos , Muñoz Teresa , Vanacker Veerle
Published: September 2022

Abstract. Vegetation plays a key role in the hydrological and biogeochemical cycles. It can influence soil water fluxes and transport which are critical for chemical weathering and soil development. In this study, we investigated soil water balance and solute fluxes in two soil profiles with different vegetation types (cushion-forming plants vs. tussock grasses) by measuring soil water content, flux, and solute concentrations and by modeling soil hydrology. We also analyzed the role of soil water balance in soil chemical weathering. The influence of vegetation on soil water balance and solute fluxes is restricted to the A horizon. Evapotranspiration is 1.7 times higher and deep drainage is 3 times lower under cushion-forming plants than under tussock grass. Likewise, cushions transmit almost threefold less water from the A to lower horizons. This is attributed to the vertical distribution of soil properties associated with the root systems. Under cushion-forming plants, DOC and metals (Al, Fe) are mobilized in the A horizon. Solute fluxes that can be related to plant nutrient uptake (Mg, Ca, K) decline with depth as expected from bio-cycling of plant nutrients. Dissolved silica and bicarbonate are minimally influenced by vegetation and represent the largest contributions of solute fluxes. Soil chemical weathering is higher and constant with depth below tussock grasses; while lower and declining with depth under cushion-forming plants. This difference in soil weathering is attributed mainly to the water fluxes. Our findings reveal that vegetation can modify soil properties in the uppermost horizon altering the water balance, solute fluxes, and chemical weathering throughout the soil profile.
Incorporating Design Thinking and behavioural techniques to design and evaluate a mobile intervention to reduce sugar consumption
Authors:   , Song Kimchheng
Published: September 2022

Current trends indicate that 75 per cent of Australians will be overweight or obese by 2025 unless an innovative and effective strategy is implemented. This thesis incorporates design thinking and behaviour theory to design and evaluate a digital approach to reduce added sugar consumption in the Australians’ diet relative to the World Health Organisation recommended guidelines.
Managerial overconfidence and success in the market for corporate control
Authors:   , Kulathunga Nisansala S.
Published: September 2022

The thesis examines the implications of the CEO’s psychological traits on firm outcomes in the market for corporate control. Employing a novel measure of the three facets of overconfidence (overestimation, overplacement and overprecision) using CEOs’ spoken words in interviews, I argue and find overconfidence to be significantly associated with M&A deal activity and outcomes. Specifically, CEO overconfidence leads to higher deal activity but lower deal completion and lower acquirer long-term stock performance. CEO power (Duality) strengthens this relationship.
Data-driven discovery of mode switching conditions to create hybrid models of cyber-physical systems
Authors:   , Hussain Mukhtar
Published: September 2022

Models are essential tools for evaluating a system’s behaviour under different scenarios. However, in industrial practice pre-existing models of cyber-physical systems (CPSs) are not always available because CPSs can be legacy systems which are subject to changes and upgrades over time that may not be well documented. System identification addresses the problem by creating models from the external observation of a system. This research is concerned with hybrid system identification of CPSs, i.e., building models of dynamic systems switching between different operating modes. This thesis presents methods for discovering data-driven mode switching conditions essential for building such models.
Sostenibilidad social y empleo como reto de la transformación digital: el nuevo sexto sector digital de la economía
Authors: Palomo Zurdo Ricardo , Dopacio Cristina Isabel , Rey Paredes Virginia
Published: September 2022

Este trabajo analiza el impacto de la transformación digital en el empleo, partiendo de los cambios que latecnología está provocando ya en muchas profesiones. Para ello, parte de la base del cambio de época que implican lanueva era digital y las tecnologías avanzadas, bajo la referencia del impacto histórico del progreso en su proceso dedesplazamiento de la mano de obra desde el sector primario al secundario, con la revolución industrial y, ahora, desde elsector terciario de servicios a un nuevo sector sexario o digital. Se trata el nuevo marco competencial para los empleos yla literatura sobre el impacto de la digitalización en los empleos del futuro, haciendo obligada referencia al rol delmodelo educativo como vector de sostenibilidad en el empleo y a la oportunidad de los fondos europeos para laformación en competencias digitales de la sociedad.
Impact of COVID -19 on Prosthetics and Orthotics Rehabilitation in India: A Cross-Sectional Study
Authors: Das Rajesh , Nayak Smita
Published: September 2022

Background: Densely populated country like India is demonstrably affected by COVID- 19 in both first and second wave. The people with disability who commonly faced challenges in daily encounters were face additional difficulties due to devoid of appropriate healthcare services and suffered a lot with psychological trauma due to lack of community participation.
Objectives: This study aimed to find out the impact of COVID 19 on Prosthetics and Orthotics professional, industry, student, private practitioner and Disabled people
Methods: A web survey was conducted in India among the Prosthetist and Orthotist professional working in Government sector, Non government organizations, Private sectors approximately 3 month after the second peak of COVID 19. The descriptive data of impact of Pandemic on profession, service provider, service user and students of this profession were collected.
Results: Eighty one professional responded to questionnaire and private sector professional were significantly affected by this pandemic as compared to government employee, The service user faced remarkable difficulties and mental trauma due to restriction as well as to understand the concept of tele-rehabilitation due to lack of accessibility to technology and knowledge.
Conclusions: The rehabilitation to the person with disabilities should be in community based, technology friendly, easy to avail and cost effective. The professionals need to be prepared well in advance to face such emergency crisis and adopt the change to overcome the challenges. Use of technology and artificial intelligence may help people with disabilities as well as professionals to overcome the crisis.

Key words: Mental health, Tele rehabilitation, Assistive technology, Activities of Daily living (ADL), Social isolation
Concept of Srotas with Special Prominence of Pranavaha Srotas: A Review
Authors: Bhatnagar Dr. Sanjay Kumar , Sharma Dr. Rajesh Kumar , Sharma Dr. Dinesh Chandra
Published: September 2022

Srotamsi is defined as the passages through which the various Dhatus (tissues) that are undergoing the process of metabolic transformation are transported. 1 In Ayurvedic classics, the term Srotas is used as a dynamic inner transport system of body-mind-spirit organization in addition to the circulatory system. Srotas are the channel or structure through which Sravanam karma i.e., flowing, moving, oozing and permeation of different constituents and nutrients of the body takes place. There are many numbers and types of Srotas mentioned by different Acharyas. Acharya Charaka had explained Srotas as a medicinal view while Acharya Sushrut had explained Srotas according to surgical aspect. According to Acharya Caraka, it is to be noted that Srotamsi is structurally similar to their corresponding tissues. They are of different shapes, such as circular, elongated and reticular.2 According to Acharya Susruta, those channels which originate in hollow organs, spread throughout the body, and purvey materials ‐ are to be understood as Srotamsi 3 But Pranavaha Srotas is the first & important Srotas, which carry Prana all over the body. It is related to the heart, lungs, and other structures like the pulmonary artery and pulmonary vein, which have been explained as vital air inhaled and also the vital energy of the body responsible for each and every activity of a living being.

Key words: Srotas, Prana, Pranavaha srotas, Udakavaha srotas, Respiratory System
Effect of Customized Resistance Training on Body Mass Index and Quality of Life in Individuals with Polycystic Ovarian Syndrome - A Randomized Clinical Trial
Authors: Chinmayee Shah Chinmayee Shah , Tahakik Dr. Sanskruti
Published: September 2022

Background: Polycystic Ovarian Syndrome is known to affect a broad spectrum of clinical manifestations associated with it are significant and include reproductive dysfunction. Many forms of physiotherapeutic interventions have been tried and tested to alleviate the symptoms. Currently, there are no studies that show a significant effect of resistance exercise and lifestyle modification as a combination to create an impact on the symptoms of Polycystic Ovarian Syndrome.
Purpose of the study: To study whether resistance exercises can alleviate the symptoms of PCOS in women of age 18-40 and compare the effectiveness of resistance exercise training in alleviating symptoms of PCOS over aerobic training and lifestyle modification.
Study design: Randomized Controlled Trial
Method: 78 individuals, aged 18-40, medically diagnosed with Polycystic Ovarian Syndrome were included in the study based on inclusion criteria with a randomized sampling technique. Women were randomly assigned into two groups. Group A (aerobic training and lifestyle modification) and Group B (resistance training). They all were given 4 weeks of treatment. Outcome measures included PCOSQ.
Results: 78 patients were included. 39 patients to lifestyle modification and 39 patients to resistance training. At the end of 4 weeks, individuals of Group A and Group B had no significant difference in all together symptoms but weight and BMI were better managed in the group with Resistance training.
Conclusion: The present study concludes that both the treatment groups had equal effectiveness in individuals with polycystic ovarian syndrome. However, the Body Mass Index and menstrual regularity were found to have a more significant positive effect in individuals with polycystic ovarian syndrome than in the group with aerobic exercise and lifestyle modification.

Key words: Polycystic Ovarian Syndrome, Body mass index, Aerobic exercises, Lifestyle modification, Resistance training
Biosorption of Cd (II), Pb (II) and Zn (II) from Aqueous Solutions using Garden Egg (Solanum Melongena) Leaf: Equilibrium, Kinetics and Thermodynamics
Authors: Adebanjo Ahmed , Babarinde Adesola , Moberuagba K.
Published: September 2022

The prevalent problems associated with heavy metal contamination of the environment particularly underground and surface wastewater compel the need to work on economical means of mitigating the accumulation of heavy metals in the environment by espousing the heavy metal biosorption option. The choice of biosorption in this regard is hinged on the overall cost control of the process and its relative effective outcome compared to other means of diminishing heavy metal accumulation in the environment. Thus, the potential of Garden Egg (Solanum melongena) Leaf (GEL) to remove Cd(II), Pb(II) and Zn(II) from aqueous solutions through biosorption was studied. The influence of various process parameters such as pH, contact time, biomass dose and initial metal ion concentration was investigated using batch experiments to determine the efficiency of the biosorbent. The presence of ionizable functional groups (-N-H,-C≡N, C=O and –C-O) in the GEL were analyzed using Fourier Transform Infrared (FT-IR) which are responsible for the binding of the cations. The heat of the sorption process was estimated from Temkin Isothermal model and mean free energy were estimated from Dubinin-Radushkevich (D-R) model. The biosorption process revealed that the best pH for Cd(II), Pb(II) and Zn(II) adsorption was at pH 7. The kinetic studies showed that the biosorption process was best represented by pseudo-second order kinetics having the highest correlation coefficient (R2) of 0.9398, 0.9339 and 0.9398 for Cd(II), Pb(II) and Zn(II) respectively, among various kinetic models tested. Equilibrium data were better represented by Freundlich isotherm among Langmuir, Freundlich, Temkin and Dubinin–Radushkevich (D–R) absorption isotherms. The Freundlich model appeared to have better regression coefficients among four Equilibrium data tested. The study on the effect of dosage showed that the dosage of the biomass significantly affected the uptake of the metal ions from solution. Thermodynamically, the biosorption of each of the metal ions was endothermic and the order of spontaneity of the biosorption process being Zn > Pb > Cd. However, positive change in entropy was observed for each and the order of disorder is Zn > Cd > Pb. The results indicate that Garden egg (Solanum melongena) leaf has a potential for the adsorption of Cd(ll), Pb(ll) and Zn(ll) and could be found useful in the treatment of industrial effluents.

Keywords: Biosorption; Heavy metals; Effluents; Garden egg; Thermodynamics; Kinetics.
Phytochemical Analysis, Antioxidant Activity and Larval Toxicity of Ethanolic and Ethyl Acetate Extracts from Rhizomes of Curcuma Longa L.
Authors: Jacques ADOVELANDE , Fresnel Boris CACHON , Fidèle ASSOGBA Mahoudo
Published: September 2022

Turmeric (Curcuma longa L.), a plant native to Asia, was the subject of the present study whose objective was to evaluate the antioxidant properties of the rhizome powder of this plant cultivated at Bopa, a commune of Benin. The methodology used consists in evaluating the toxicity of the extracts by the shrimp larvae, to make the phytochemical analysis of the Curcuma longa L. powder in order to obtain information on its biochemical and/or chemical value. It also consists in the determination of polyphenols, flavonoids, tannins and beta-carotene of ethanolic and ethyl acetate extracts, and in the evaluation of the antioxidant activity of these extracts by the FRAP and DPPH methods. Phytochemical screening of the powder revealed the presence of alkaloids, flavonoids, anthocyanins, tannins, steroids and terpenes, reducing compounds, mucilages and anthracene derivatives. The yield of ethanolic and ethyl acetate extracts gave 31.94 % and 14.66 % respectively. The larval toxicity test performed on these two extracts revealed that they will not be toxic. The ethyl acetate extract had a high content of polyphenol (1304.596 mg EqAG) while for the flavonoids (1259.938 mg EqQ/g E), tannins (259.859 mg EqP/g E) and beta-carotene (0.139 mg/100 g) assay, the ethanolic extract had the highest contents. Note also that the ethyl acetate extract showed the best antioxidant activity (IC50 = 0.007 mg/mL) compared to the ethanolic extract (IC50 = 0.009 mg/mL) after the control (ascorbic acid 0.0074 µg/mL).

Keywords: antioxidant activity, phytochemical analysis, rhizome, larval toxicity
Hospital Business Strategy in the Era of National Health Insurance at Asysyifaa Leuwiliang Hospital
Authors: Yusniawati Eka , Suroso Arif Imam , Arifin Amzul
Published: September 2022

This research was conducted at Asysyifaa Hospital, Leuwiliang, Bogor Regency and in general this study aims to determine the right business strategy so that the hospital business can continue to grow and develop amid its support for the successful implementation of the National Health Insurance (JKN). BPJS Kesehatan is part of JKN which is a government policy in the health sector and aims to realize the implementation of providing decent health insurance for all Indonesians. The strategy that has been implemented by Asysyifaa Hospital Bogor needs to be developed based on the Business Model Canvas (BMC), IE Matrix, SWOT Analysis, and the four framework approach on the Blue Ocean Strategy, so that a new business model is obtained. Data were collected by interviews with informants. The selection of informants is determined through purposive sampling techniques. In addition data were obtained through questionnaires with the same informants, and a study of the literature. Several new strategies were successfully formulated and outlined in several elements of the business model of asysyifaa Hospital. Such improvements need to be developed and maintained in accordance with current conditions.

Keywords: SWOT analysis, business model canvas, hospital industry, National Health Insurance (JKN), business strategy, blue ocean strategy.
The Implementation of a Complete Systematic Land Registration Program in Kebumen Regency, Indonesia
Authors: Cahyono Joko Pitoyo , Indiahono Dwiyanto , Rosyadi Slamet
Published: September 2022

Implementation of land policies continues to encounter several barriers; thus, the community continues to experience many land conflicts. This study aims to identify and analyze aspects of communication, resources, disposition, and bureaucratic structure in relation to the success of implementing the complete systematic land registration program in Kebumen Regency. This study was undertaken in the Kebumen Regency setting and employed qualitative methodology. Through interviews, observation, and documentation, data was collected. Using the approach of interactive model analysis and the triangulation procedure, the validity of the data was determined. The findings of the research indicate that the communication element, comprising the publishing mechanism, coordination system, and information dissemination, has been operating effectively. First, the lack of human resources as a driving team; second, the mutually agreed-upon self-financing is considered too costly for such individuals; and third, the government subsidies offered by the Kebumen Regency are insufficient. Such factors include things such as aspects of the disposition and organization of personnel. The regions with a high degree of complete systematic land registration programs that can be mobilized independently in areas that manage them have a low district government's commitment and involvement in setting the budget for complete systematic land registration, an adjudication committee that does not meet the structure, and a lack of support from the village government to mobilize community participation. The complete systematic land registration committee creation at the village level did not even go as well as it should have in terms of the people who did the work.

Keywords: Bureaucratic Structure, Communication, Disposition, Implementation, Land Policy, Resources
Implementation of E-learning in EFL Context during COVID-19: Teachers' and Students' Views at One School
Authors: Wahyuningsih Sri , Kusumaningrum Indah
Published: September 2022

The present study reports the implementation of e-learning in English language teaching during the COVID-19 pandemic at one of the private high schools in Indonesia viewed from teachers' and students' perspectives. Using a qualitative study, the data were garnered through semi-structured interviews with an English teacher, a principal who also teaches English, and students. The result reveals that both teachers and students have the same responses to e-learning practices. There were three stages in implementing e-learning: preparation, implementation, and evaluation. In terms of preparation, the English teacher designed lesson plans as a guideline for learning. In the implementation stage, the English teacher used learning materials from various sources, including textbooks, videos, articles, and other sources on the internet. On the other hand, students reported that English teaching and learning activities in e-learning classes were usually carried out through WhatsApp, Google Classroom, and Zoom meetings. Apart from the advantages of e-learning in English language teaching, some challenges in its practice include the difficulties of operating technical devices for specific teachers, the problems of controlling students during distance learning, etc. Finally, the study's findings promote integrating technology and encouraging teachers' professional development in English language teaching.
Bisexuality in Bohemian Rhapsody: A Queer Study
Authors: - Syabilla Maylya , Mamik Tri Wedawati
Published: September 2022

This research was meant to describe the shape of sexuality in Bryan Singer's "Bohemian Rhapsody" (2018) by analyzing the main character from the Queer perspective. Bisexual is a term used to describe relationships of people both with the same sex and the opposite sex for a certain period, including being attracted to or having sexual activity. Bohemian Rhapsody discusses Queen's career journey by showcasing the lead singer as a highlight. Freddie struggles to live in a world of hedonism and stigma, preconceptions, and the erasure of Bisexuality as a social identity. It will answer how to construct binary desires and how society shapes them by applying theory from Butler's work "Gender Trouble." to fulfil this study; In this study, either textual or visual film analysis will be applied to the subsequent discussion. 1.) Determine forms of Bisexuality in Bohemian Rhapsody; 2.) Reveal Bisexuality towards the character interactions in Bohemian Rhapsody. Through this interpretation, bisexual visibility is frequently devalued and forced to join monosexism with similar terms such as gay and lesbian, resulting in the erasure of Bisexuality. This behaviour is predicated on the social and cultural stereotypes attached to "bisexual."
Corporate Social Responsibility and Firm Performance in the Indian Context
Authors: HAYAT Feeroz , NAIM Hamza , AZIZ Tariq
Published: September 2022

In this study, we examine the impact of Corporate Social Responsibility (CSR) as a measure of Corporate Governance on firm performance for 348 firms in the NSE 500 Index listed in the National Stock Exchange (NSE) of India for the period 2012-2019. The results show that the total amount spent on CSR by the firms has a negative impact on the firm performance as there is a significant difference between the total amount incurred to be spent on CSR as per amendments in the Companies Act, 2013 and the total amount actually spent on CSR by the firms. It’s concluded that the number of CSR meetings held had no significant impact on firm performance. Results also show that firm size moderates the relationship between CSR and firm performance.
CHARACTERISTICS OF LUNG-RADS 4A AND 4B CATEGORY NODULES DETECTED DURING LUNG CANCER SCREENING USING LOW-DOSE COMPUTED TOMOGRAPHY
Authors: PANINA A. , ZHOLDYBAY Zh. , TURKINBAEV E. , SEISENBAEV T. , TUSUPOVA A. , MUKHAMEDZHAN A.
Published: September 2022

Relevance: With the introduction of low-dose lung cancer screening, it became necessary to study the radiological characteristics of
detected nodules to determine the optimal tactics for managing patients, reduce mortality by detecting early stages, and reduce the number
of false-positive results.
The study aimed to investigate the radiological semiotics of lung lesions detected by low-dose lung cancer screening and classified
as categories 4A and 4B according to the Lung-RADS 1.1 and establish the relationship between their characteristics and possible malignancy.
Methods: We studied the results of 167 LDCT images of the chest. All LDCT examinations were performed on CT scanners with a low
dose protocol that did not exceed 1 mSv.
Results: Of the 167 identified lesions in the lungs, 89 (53.3%) were pathologically verified: 6 (7.1%) cases from the Lung-RADS 4A
category and 83 (100%) from the Lung-RADS 4B category. According to pathomorphological examination, 74 (83.1%) out of 89 participants had malignant tumors. In the studied categories, the association between the development of lung cancer and gender Odds Ratio was
statistically significant – 2.320 (95% CI 1.230-4.376). Most lung cancer cases had solid nodules (83.8%) with tuberous contours (43.2%),
a density of 20-35 HU, and the reaction of the adjacent pleura (58.1%).
Conclusion: The study of pathognomonic radiological characteristics of lung lesions will improve the early diagnosis of lung cancer
and reduce the number of false-positive results
Application of Ozone Therapy in Dentistry
Authors: Basudan Thuraya , Alzurqi Nada , Alzahrani Naif , Bormah Dania , Alharbi Rahaf , Bukhamsin Fatema , Aljarid Danah , Alruqi Alanoud , Alghunaim Ghadah , Alharbi Amal , Aldrees Shorouq
Published: September 2022

Ozone refers to a tri-atomic oxygen molecule and is present in stratosphere abundantly. Ozone is known to have multiple medical and dental properties. Use of ozone therapy in the field of dentistry dates back to 1930s where wound healing and disinfection were its initial use. Later, owing to its properties its use expanded to treatment of various oral disorders. Ozone treatment has been more effective than conventional therapies that follow a less invasive and conservative approach to dental treatment. The purpose of this research is to review the available information about applications of ozone in dentistry. Ozone treatment has so far been used for wound healing, tooth decay, oral lichen planus, gingivitis, periodontitis, halitosis, osteonecrosis of the jaw, postoperative pain, plaque and biofilms, dentin hypersensitivity, temporomandibular joint disorders, among several others. Ozone has been successfully transformed the oral and dental treatment. Ozone therapy is a very effective treatment with no side effects or pain. It also reduces the patient's anxiety and level of stress as it reduces the duration of treatment. Ozone provides a painless alternative to the common treatment of tooth decay and has been proven to stop root decay, pits and fissure and relieve ulcers clinically. Its anti-microbial action against endodontic flora is quite promising, however more clinical research and trials in future can be beneficial.