bluuebunny/crossref_metadata_2025 huggingface dataset:
Pediatric Thyroid Lesions: Synergistic Role of Clinical and Cytological Features in Diagnosis
Authors:   Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Singh Anurag , Prasad Pallavi ,   Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Singh Alka ,   Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Published: May 2023

INTRODUCTION: Thyroid lesions in childhood and adolescence are uncommon, and the risk of malignancy widely varies. They require careful evaluation and more aggressive diagnostic approach. The present study aimed to evaluate the frequency of various pediatric thyroid lesions in pediatric cases with thyroid nodules and ascertain the utility of clinical, laboratory, ultrasonography, and fine-needle aspiration cytology (FNAC) findings to discriminate between benign and malignant lesions. METHODS: A retrospective study where 95 consecutive cases of pediatric patients with thyroid nodules received over six years (January 2016–December 2021) were retrieved from the hospital information system. The differences in clinical, laboratory, ultrasonography, and cytological findings between benign and malignant lesions were analysed. Statistical analysis was performed using SPSS software (version 21.0). RESULTS: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) was used to categorise the cases into: unsatisfactory (n=3), benign (n=66), intermediate (n=8) and suspicious/malignant (n=18). The specificity of cytopathology in diagnosing benign lesions (TBSRTC-II) was 90%, whereas sensitivity in diagnosing malignant lesions (TBSRTC-VI) was 100%. Colloid nodule (n=57) and papillary thyroid carcinoma (n=15) were the most common benign and malignant lesions encountered respectively. Malignant lesions more frequently showed the presence of palpable lymph nodes (p-value 0.001), microcalcifications (p-value 0.001) and intranodular vascularization (p-value 0.01). CONCLUSION: The diagnosis of pediatric thyroid lesions should be based on a multistep evaluation that includes clinical, laboratory, and radiographic modalities. Thyroid function tests and ultrasonography can help identify clinically unapparent thyroid nodules and provide detailed nodule characterization for suspected malignant lesions. FNAC is a simple, less-invasive, and costeffective technique that can differentiate between benign and malignant thyroid lesions.
A VOCAÇÃO HISTORIOGRÁFICA DA HISTÓRIA FEMINISTA DA ARTE
Authors: Pinheiro Machado Kern Daniela
Published: May 2023

Através da análise de um conjunto de obras representativas da história feminista da arte dos anos 1970 e 1980, de autoras seminais para esse campo de estudos, a saber, Linda Nochlin, Ann Sutherland Harris, Germaine Greer, Roszika Parker e Griselda Pollock, pretende-se, no presente trabalho, explorar a preocupação com historiografia da arte comum a todas elas. Em um cenário de disputa de narrativas-mestras e de tentativa de inserção de artistas, colecionadoras, curadoras e marchands mulheres nas linhas gerais dos grandes manuais de história da arte, a historiografia tem se mostrado um cenário privilegiado para esses embates, e a busca pelas raízes historiográficas dessas discussões, nas figuras de Plínio o Velho, Boccaccio e Vasari, marca a obra inicial das autoras aqui estudadas.Palavras-chave: História feminista da arte; Historiografia da arte; Artistas mulheres.THE HISTORIOGRAPHIC VOCATION OF FEMINIST ART HISTORY Abstract: Through the analysis of a set of works representing feminist art history from the 1970s and 1980s, by seminal authors in this field of study, namely Linda Nochlin, Ann Sutherland Harris, Germaine Greer, Roszika Parker and Griselda Pollo­ck, we wish to explore, in the present work, the preoccupation with art historiography common to all of them. In the scenario of master narratives and the attempted insertion of women artists, collectors, curators and art dealers in the broad lines of art history’s great manuals, historiography has been a privileged context for these conflicts, and the search for historiographical roots of such discussions in the figures of Pliny the Elder, Boccaccio and Vasari marks the initial work of the authors studied here. Keywords: Feminist art history; Historiography of art; Women artists.
VENTRA – ESTADOS DE MOVIMENTOS
Authors: Fogaça Lopes Pâmela
Published: May 2023

Resumo: Relato da produção da vídeo-performance Ventra – estados demovimentos realizada pelos alunos do Programa de Mestrado em Artes Visuais da Universidade Federal de Pelotas - UFPel, 2019, Pelotas/RS, Brasil.Palavras-chave: Vídeo-performance; Improvisação; Composição. VENTRA - MOVEMENT STATESAbstract: This is a report on the production of the video-performance Ventra - states of movements carried out by the students of the Graduate Program in Arts - Master in Visual Arts at the Federal University of Pelotas - UFPel, 2019, Pelotas/RS, Brazil.Keywords: Video-performance; Improvisation; Composition.
Uma (Breve) Introdução ao Pensamento Pós-Estruturalista
Authors: De Mendonça Daniel
Published: May 2023

Neste artigo, proponho um caminho para organizar a tarefa inicial de compreensão do pós-estruturalismo. Trata-se de um trajeto que inicia com as análises estruturais de Ferdinand de Saussure e Claude Lévi-Strauss, passa pela discussão ontológica de Martin Heidegger sobre o fundamento e, finalmente, chega na desconstrução estrutural de Jacques Derrida. Meu objetivo não é falar exaustivamente sobre cada um dos autores, mas, a partir de categorias centrais dos seus pensamentos, apontar um caminho para uma compreensão geral do pós-estruturalismo.Palavras-chave: Pós-estruturalismo; Pós-fundacionalismo; Lévi-Strauss, Heidegger; Derrida.A (Short) Introduction to Post-Structuralist Thought Abstract: In this article, I propose a way to organize initial steps for comprehending post-structuralism. It is a path that begins with Ferdinand de Saussure and Claude Lévi-Strauss' structural analyses, and then proceeds toward Martin Heidegger's ontological discussion of the ground and, finally, arrives at Jacques Derrida's structural deconstruction. My goal is not to talk about each of these authors comprehensively but, using main categories of their thought, to point out a pathway for a general comprehension of post-structuralism.Keywords: Post-structuralism; Post-foundationalism; Lévi-Strauss; Heidegger; Derrida.
Porque esperamos [notas sobre a docência, a obsolescência e o vírus]
Authors: Bedin da Costa Cristiano
Published: May 2023

[RESENHA DE LIVRO] Porque esperamos [notas sobre a docência, a obsolescência e o vírus] / Angélica Vier Munhoz, Cristiano Bedin da Costa, Sergio Andrés Lulkin (organizadores). 1.ed. – Porto Alegre: UFRGS, 2020. Disponível em: https://lume.ufrgs.br/handle/10183/210654Palavras-chave: Esperar; Docência; Vírus. Why we wait [notes on teaching, obsolescence and the virus] Abstract: [BOOK REVIEW] Why we hope [notes on teaching, obsolescence and the virus] / Angélica Vier Munhoz, Cristiano Bedin da Costa, Sergio Andrés Lulkin (orga­nizers). 1.ed. - Porto Alegre: UFRGS, 2020. Available at: https://lume.ufrgs.br/hand­le/10183/210654.Keywords: Waiting; Teaching; Virus.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy
Authors: Southwell Nneka , Primiano Guido , Nadkarni Viraj , Attarwala Nabeel , Beattie Emelie , Miller Dawson , Alam Sumaitaah , Liparulo Irene , Shurubor Yevgeniya I , Valentino Maria Lucia , Carelli Valerio , Servidei Serenella , Gross Steven S , Manfredi Giovanni , Chen Qiuying , D'Aurelio Marilena
Published: May 2023

Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy‐dependent, mitochondrial diseases often affect skeletal muscle. Although genetic and bioenergetic causes of OXPHOS impairment in human mitochondrial myopathies are well established, there is a limited understanding of metabolic drivers of muscle degeneration. This knowledge gap contributes to the lack of effective treatments for these disorders. Here, we discovered fundamental muscle metabolic remodeling mechanisms shared by mitochondrial disease patients and a mouse model of mitochondrial myopathy. This metabolic remodeling is triggered by a starvation‐like response that evokes accelerated oxidation of amino acids through a truncated Krebs cycle. While initially adaptive, this response evolves in an integrated multiorgan catabolic signaling, lipid store mobilization, and intramuscular lipid accumulation. We show that this multiorgan feed‐forward metabolic response involves leptin and glucocorticoid signaling. This study elucidates systemic metabolic dyshomeostasis mechanisms that underlie human mitochondrial myopathies and identifies potential new targets for metabolic intervention.
Machinability Study in Turning of Ti-6Al-4V under CO2-based Vortex Tube Cooling System
Authors: Khirod Mahapatro  , Pasam Vamsi krishna
Published: May 2023

The study on the machinability of titanium alloys provides new ways to minimize the difficulty levels of machining the alloys due to substantial heat accumulation. To improve machinability, pivotal factors such as heat accumulation and cutting temperature must be regulated. In this study, a turning operation was performed on Ti-6Al-4V and the cutting temperature was reduced by supplying cooled CO2 gas through a vortex tube connected with two nozzles. Variations in cutting force, cutting temperature, and surface roughness with cutting speed, feed, and depth of cut were recorded. Subsequently, responses were compared for single nozzle vortex tube, dry, and compressed air environments at different cutting speeds. Cutting force and surface roughness followed a similar trend which increased with decreasing speed, and increasing feed and depth of cut. The cutting temperature increased with all three variables. The proposed cooling system provided better results in terms of cutting temperature and surface roughness, while a marginally higher cutting force was observed compared to dry cutting
Implementing circular economy in the construction sector: Evaluating CE strategies by developing a framework
Authors: Hosseini Zahra , Laratte Bertrand , Blanchet Pierre
Published: May 2023

Among various industries, the construction sector has one of the greatest impacts on the environment. Minimizing the resource use and the waste outputs in this sector could be fulfilled by applying circular economy (CE) strategies. Although research on CE in the construction sector has increased in recent years, there have not been remarkable adjustments by applying these strategies to the construction industry. The purpose of this study was to examine the impacts of using CE strategies in the construction sector. A framework was adapted to guide the application of different CE strategies at the end-of-life of buildings. The framework was assessed by a case study of a residential building in mass timber. This study evaluated the application of CE strategies from the environmental aspect with the life cycle assessment (LCA) method. The results confirmed that circular strategies can deliver lower environmental impacts.
ANALISIS KELAYAKAN USAHA TERASI UDANG REBON DI KELOMPOK PENGOLAH DAN PEMASAR (POKLAHSAR) SETYA BAKTI DESA SIRNOBOYO KECAMATAN PACITAN KABUPATEN PACITAN
Authors: Nugraha Jefri Putri , Mareta Zayafika , Suseno Dewi Alima Nostalia , Waluyo Buyung Purnomo
Published: May 2023

The processing of rebon shrimp paste has been widely carried out by people in the coastal area of Pacitan as a side activity in increasing family economic income and also participating in national development efforts in the fisheries sector. This study aims to measure the feasibility of rebon shrimp paste processing business based on financial (financial) aspects. This research was conducted during September 2022, in Sirnoboyo Village, Pacitan District, Pacitan Regency, East Java. This study uses a quantitative descriptive research method. Descriptive quantitative research method is a method that aims to make pictures or descriptive of a situation objectively using numbers, starting from data collection, interpretation of the data and appearance and results. Sampling of the research was carried out on rebon shrimp shrimp paste entrepreneurs, members of Poklahsar Setya Bakti in Sirnoboyo Village. The feasibility of a business from the financial aspect is measured using the analysis of discounted investment criteria, namely the net present value, the rate of return on investment capital (internal rate of return), the ratio of net benefits to costs (net benefit cost ratio), investment return period (payback period). The shrimp paste processing business carried out by members of Poklahsar Setya Bakti in Sirnoboyo Village has good prospects for development in the future. This business is financially feasible with NPV = Rp. 32,667,112,-. IRR = 21%, Net B/C = 2.1 and a payback period of 3.3 years.
APLIKASI PAKAN ALAMI DAN BUATAN PADA PEMELIHARAAN LARVA UDANG VANNAME (Litopenaeus vannamei) DI HATCHERY PT. SURI TANI PEMUKA UNIT HATCHERY NEGARA, BALI
Authors: Aonullah Asep Akmal , Manida Aliyati
Published: May 2023

This study aims to determine the application of live and artificial feed in the rearing of vanname shrimp larvae (Litopenaeus vannamei). The work consists of preparation of rearing media, nauplii stocking, feed management and monitoring of larval rearing. A total of 2,000,000 nauplii were used and reared in concrete tanks with a water volume capacity of 14 tons equipped with a filtration system and water changes carried out by flowtrough and circulation. The feed used consisted of livel feed including Chaetoceros muelleri, Thalassiosira sp and Artemia sp. and also artificial feed (commercial feed). The results showed that the application of live and artificial feed during larval rearing was positively correlated with larval stadia development and larval survival rate. Larval development in each stadia, including zoea, mysis and post larvae, showed normal development. The total larval population at each stadia decreased with a final mortality value of 40%. Nevertheless, the survival rate until the end of the PL-10 rearing period was observed to be 60% and this condition was in optimal condition
FUEL CONSUMPTION ANALYSIS ON THE PUTRA MAKMUR 86 VESSEL
Authors: Nugraha I Made Aditya , Idrus Muhamad Amril , Luthfiani Febi , Malelak Frengky Yeremias
Published: May 2023

The vessel's operation can run smoothly supported by reliable machines and can run effectively and efficiently. This reliability can be achieved through maintenance efforts, the right technology, and good fuel usage. Putra Makmur 86 vessel is one of the fishing vessels owned by PT. Matsyaraja Arnawa Satambhapura and operates in East Nusa Tenggara. This ship uses diesel fuel to support the performance of its engines. The use of this fuel is used to drive the main engine and two generators. Optimal use of fuel will of course have an impact technically and economically. The importance of the need for fuel on the ship's engine and the lack of information about the performance of the engines on the ship, so in this paper, an attempt is made to analyze the use of fuel and the performance of the main engine and generator during operation. The methods that were used in this study are observation, interviews, and analysis of fuel calculations are used in this study. Based on the results of operating activities for 32 days, the use of fuel on the Putra Makmur 86 Ship during its operation was very effective and efficient. Savings in the use of diesel fuel can be achieved by as much as 2.76% (0.21 Tons). This can be seen from the difference between direct observation and calculation of fuel consumption. The cause of this difference is the influence of good weather and currents during operation, shipping routes, engine conditions that are still good, payload, and good driving style so that fuel consumption is not too much.
Efficacy of catheter treatment of atrial fibrillation in patients with myocarditis depending on the adrenoreaction of the body (a prospective single-center study)
Authors: Archakov Evgenii A. , Batalov Roman E. , Eshmatov Otabek R. , Stepanov Ivan V. , Muslimova Elvira F. , Rebrova Tatyana U. , Afanasyev Sergey A. , Popov Sergey V.
Published: May 2023

Background. Worldwide, research continues into various factors that may influence the success of catheter treatment of atrial fibrillation. In this regard, the influence of the state of the sympathoadrenal system of the body has not been studied enough. Aims to evaluate the effectiveness of interventional treatment of atrial fibrillation (AF) in patients with and without myocarditis, depending on the level of beta-adrenergic responsiveness of the organism. Materials and methods. The study sample included 40 patients. Of these, 27 (67.5%) are men. The age in the sample was 49 (44; 55) years. The study included 25 (62.5%) patients with paroxysmal AF, 10 (25.0%) with persistent and 5 (12.5%) with long-term persistent. All patients underwent surgical treatment of AF using radiofrequency (RFA) or cryoablation (CBA). Endomyocardial biopsy was performed in 18 patients to verify the diagnosis. Beta-adrenergic responsiveness (beta-ARM) was assessed in dynamics 3 days after surgery, 3 months and 12 months. The follow-up period for patients was 12 months. Results. All patients underwent surgical treatment of AF, in 7 cases (17.5%) CBA of the pulmonary veins was performed, in 33 (82.5%) cases RFA was performed. According to the biopsy results, signs of myocarditis were detected in 9 patients (22.5%). Focal myocarditis was found in 7 patients, diffuse in 2. The effectiveness of catheter treatment in general was 72.5%, for CBA 71.5%, for RFA 73.5%. Beta-ARM before ablation was 19.16% [12.46; 27.46], 3 days after ablation 24.43% [15.38; 33.65], after 3 months was 20.27% [9.90; 27.71], in 4 patients after 12 months, beta-ARM was 32.5% [20.0; 43.2]. The dynamics and influence of beta-ARM on the effectiveness of interventional treatment of AF in patients with early and late relapses, the presence of myocarditis was assessed. Conclusions. The results obtained showed no effect of the level of beta-ARM on the effectiveness of RFA and CBA in patients with and without myocarditis. Beta-ARM showed no association with the development of early arrhythmia recurrences after ablation. No statistically significant differences were found when comparing beta-ARM levels in patients with and without diagnosed myocarditis.
Cardiovascular and oncological diseases — focus on modifiable risk factors and modern pathogenetic aspects
Authors: Buziashvili Jurij I. , Stilidi Ivan S. , Mackeplishvili Simon T. , Asymbekova El’mira U. , Tugeeva Elvina F. , Artamonova Elena V. , Akildzhonov Firdavsdzhon R. , Rakhmanzhanov Alier A. , Golukhova Elena Z.
Published: May 2023

Currently, in modern medicine, there has been a sharp increase in interest in the combined pathology of cardiovascular diseases (CVD) with other nosologies, such as diabetes mellitus, chronic kidney disease, and oncopathology. Over the past decades, there have been large positive shifts in survival in this cohort of patients. An integral specialty of cardio-oncology is rapidly developing, which is aimed at improving the results of treatment of oncological patients. Due to increased life expectancy and improved long-term prognosis in cancer patients, in particular, the adverse effects of anticancer therapy have attracted great attention from researchers. The causal relationship between cancer and CVD can be partly explained by a common profile of modifiable and non-modifiable risk factors. There is also strong evidence that a systemic inflammatory response is a common pathophysiological determinant of cancer and CVD. General risk factors for development and progression, as well as pathogenetic mechanisms, contribute to high mortality rates. Increasing knowledge of pathophysiological mechanisms will help elucidate the general molecular aspects of carcinogenesis and cardiovascular disease. This review presents general modifiable risk factors and current pathogenetic aspects of cardiovascular and oncological diseases.
Interventional approaches in atrial fibrillation
Authors: Filatov Andrey G. , Golukhova Elena Z.
Published: May 2023

One of the most common heart rhythm disorders today is atrial fibrillation (AF). Worldwide, there are about 33 million people suffering from AF. In Europe, this number is more than 6 million, in Russia about 2.5 million people. Initially, the main method of treatment was drug therapy. However, with the development of modern technologies, possible mechanisms for the development and maintenance of AF have a crucial importance. In connection with the emergence of new theories, there are also new methods of surgical and/or interventional treatment of AF. The article provides a comprehensive analysis of the current state of interventional treatment of patients with various forms of atrial fibrillation.

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Panoramic radiography and cone-beam computed tomography to measure distances between root apexes and anatomical structures
Authors:   Department of Restorative Dentistry, Endodontics division, Institute of Science and Technology, São Paulo State University - UNESP, Henrique Ferrari Carlos ,   São José dos Campos, São Paulo, Brazil., Abu Hasna Amjad ,   Department of Restorative Dentistry, Endodontics division, Institute of Science and Technology, São Paulo State University - UNESP; São José dos Campos, São Paulo, Brazil.
Published: May 2023

Aim: To compare the accuracy of the panoramic radiography with cone-beam computed tomography (CBCT) scans in measuring the distances between root apexes and the adjacent anatomical structures including the maxillary sinus and the mandibular canal. Material and Methods: A total of 200 CBCT scans (100 maxillary and 100 mandibular) from patients who also had corresponding panoramic radiography were selected. Linear measurements (in mm) presenting centralized image were made between the apexes of the maxillary teeth and the inferior wall of the maxillary sinus, and between the apexes of the mandibular teeth and the superior border of the mandibular canal by using specific software for panoramic radiography and the measurements on the coronal sections in CBCT scans. Data were submitted to inferential statistical analysis and Student’s t-test for comparison between measurements. Results: CBCT scans were significantly more accurate than panoramic radiography to measure the distances between the apexes of the maxillary teeth and the inferior wall of the maxillary sinus (p<0.05) and between the apexes of the mandibular teeth and the superior border of the mandibular canal or mental foramen (p<0.05). Conclusion: CBCT scans present more accurate measurements than panoramic radiography.
Lingual supplementation may not be required after articaine buccal infiltration anesthesia for lower molar extraction: A clinical comparative study
Authors:   Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Mosul, Mosul, Iraq, Majid Omer Waleed , Muhammad Zaid Abdulazeez ,   Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Mosul, Mosul, Iraq
Published: May 2023

Purpose: To investigate the anesthetic effectiveness of buccal infiltration (BI) versus buccal plus lingual infiltration (BI+LI) of 4% articaine for intra-alveolar extraction of erupted mandibular molar teeth Material and Methods: Eighty patients were included in this prospective clinical study. They were randomly divided into 1 of 2 equal groups: the 1st group received BI of 4% articaine 1.8 ml and LI of 0.5 ml, while the 2nd group received 4% articaine 1.8 ml BI plus 0.5 ml LI of normal saline. Another 1.8 ml articaine BI was given if initial anesthesia was inadequate. Outcome variables included pain, which was rated by patients at 3 intervals using visual analogue scale, and lingual anesthesia and patients' satisfaction which were measured using 5-score verbal rating scale. Data analyses used were descriptive statistics, t test, χ2 test, and Pearson's correlation coefficient. P-value value less than 0.05 was considered significant Results: There were 46 females and 34 males and the mean age was 35.3 years. All outcome variables were comparable between the two study groups (p˃0.05). Anesthesia was successful in 78% and 88% of cases in the (BI) and (BI+LI) groups respectively with no significant difference (p=0.2392). The mean articaine volume used was 2.5 ml and 2.87 ml respectively without significant difference (p=0.090). Conclusion: The anesthetic efficacy of (BI) alone and (BI+LI) of 4% articaine was comparable. When given in an adequate dose, articaine (BI) alone could be justified as an anesthetic option for the intra-alveolar extraction of mandibular molar teeth.
Seeking Racial and Ethnic Parity in Preschool Outcomes
Authors: Lillard Angeline S. , Tong Xin , Bray Paige M.
Published: May 2023

Montessori pedagogy is a century-old, whole-school system increasingly used in the public sector. In the United States, public Montessori schools are typically Title I schools that mostly serve children of color. The present secondary, exploratory data analysis examined outcomes of 134 children who entered a lottery for admission to public Montessori schools in the northeastern United States at age 3; half were admitted and enrolled and the rest enrolled at other preschool programs. About half of the children were identified as White, and half were identified as African American, Hispanic, or multiracial. Children were tested in the fall when they enrolled and again in the subsequent three springs (i.e., through the kindergarten year) on a range of measures addressing academic outcomes, executive function, and social cognition. Although the Black, Hispanic, and multiracial group tended to score lower in the beginning of preschool in both conditions, by the end of preschool, the scores of Black, Hispanic, and multiracial students enrolled in Montessori schools were not different from the White children; by contrast, such students in the business-as-usual schools continued to perform less well than White children in academic achievement and social cognition. The study has important limitations that lead us to view these findings as exploratory, but taken together with other findings, the results suggest that Montessori education may create an environment that is more conducive to racial and ethnic parity than other school environments.
Differentiation of wages of workers and employees of Siberian Krai (1925–1929): Decile coefficients and the Gini index
Authors:   Altai State University, Vladimirov Vladimir N.
Published: May 2023

The aim of the study is to identify specific features differentiating incomes of the part of the urban population of Siberia whose incomes were determined mainly by the size of wages. These are workers and employees of state enterprises and organizations. The chronological framework is the second half of the 1920s. Wage inequality is considered on the basis of data on its differentiation among workers in all branches of industry and office employees. An informative source for studying the issues of wage differentiation of workers in Siberian Krai is Byulleten’ statistiki truda Sibirskogo kraya [Bulletin of Labor Statistics of Siberian Krai] published in 1926–1928 and its continuation Byulleten’ statistiki truda i promyshlennosti [Bulletin of Labor and Industry Statistics] published in 1928– 1929. Their data confirm the high level of Siberian statistics of the NEP period, which has already been stated by researchers. Each issue of the Bulletin, in addition to statistical tables, charts and graphs, contains detailed comments by experts on the methods of data collection and processing. Based on the source information, I have formed two data arrays. The first of them is related to the differentiation of workers’ wages presented in the form of an interval scale. Surveys were conducted once a year in March for 4 years – from 1926 to 1929. As for the second set of data (those covering employees), they are available only for March 1926 and March 1927. During the study all available data were entered into appropriate tables and processed in the Microsoft Excel spreadsheet program. The decile coefficient and the Gini index were also calculated. For 4 years, the inequality in the wages of workers decreased significantly. The decile coefficient fell from 3.56 to 2.50, while the Gini index fell from 0.25 to 0.19. Among employees, there was a slight increase in the level of inequality. The situation with wage differentiation gradually stabilized over the entire period and remained unchanged in 1928–1929 having reached its limit. This indicates the victory of the leveling trend in the wage policy towards industrial workers in Siberian Krai.
Self-perceived health among older adults in Tomsk Oblast
Authors:   Tomsk Polytechnic University, Taran Ekaterina A. , Malanina Veronika A. ,   Tomsk Polytechnic University; Tomsk State University, Klemasheva Elena I. ,   Tomsk Polytechnic University
Published: May 2023

This article aims to identify the factors presumably contributing to the self-perception of health of older adults. Subjective assessments of health, resilience, life satisfaction, happiness are becoming increasingly valuable along with objective quality-of-life measurements. The dataset for the research was collected on the basis of a sociological survey conducted among 400 older adults (aged 55+) in Tomsk Oblast in April 2021. The survey sample is representative for the region in terms of gender and urban-rural balance. The questionnaire was designed in accordance with the methodology and practices of regular cross-sectional international and all-Russia surveys, namely the European Social Survey (ESS) and the Comprehensive Monitoring of Living Conditions (CMLC). We were also granted permission to use the verified version of the Connor-Davidson Resilience Scale (CD-RISC-25) in Russian from the authors of this methodology. Thus, we present novel empirical data to understand how factors of older adults’ subjective wellbeing are interconnected. Descriptive statistics show that for Tomsk older adults mean self-perceived health assessment reaches 5.5 on a 10-score scale. Higher self-perceived health is registered among men, persons living with a partner, persons without disabilities, employed persons, and rural dwellers. The assessments of happiness, life satisfaction, satisfaction with filial support, communications and resilience are above average. About 30% of the sample are full-time or bridge-employed. All things considered, 42% cannot afford buying anything but food and one third can only buy food, clothes and footwear. We built linear models, ttests and ANOVA with self-perceived health as a dependent variable and a range of socio-demographic characteristics, subjective assessments of well-being, financial status, social interactions and physical activity as independent variables. The results show that self-perceived health is interrelated positively, significantly (р < 0.01) and strongly (high R squared) with life satisfaction (0.402) and happiness (0.368). Other probable predictors like resilience, financial hardship, social interactions, physical activity and satisfaction with filial support fail to show considerable contribution to health self-assessment. Self-perceived health is highly positively correlated with comparative health and total resilience. We can also trace close interrelations between independent variables, namely, happiness and life satisfaction (.667**), happiness and resilience (.448**), which is common for most international surveys and proves the reliability of the data collected.
Research Library of Tomsk State University and the mythologeme of the development of Siberia: The main milestones (1878–1934)
Authors:   Tomsk State University, Konev Kirill A. , Vasilyev Artyom V. ,   Tomsk State University
Published: May 2023

The Research Library of Tomsk State University, which is now one of the largest university libraries in Russia, was established simultaneously with the university. Along with the first museums, the Botanical Garden and other university departments, it was almost immediately incorporated into the process of developing the transboundary Siberian space. To date, the history of the TSU Research Library is presented in generalizing and individual works dedicated to its employees, funds and collections, practices of interaction with readers and partners. At the same time, it seems relevant to identify the role of the Research Library as an actor involved in the process of constructing images of Siberia. This is due to the institutional involvement of the library in the complex of interactions within and around the university that has developed over decades. This involvement also makes the library a “memory space”, participating in the formation of images of the past, present and future at various levels – material, symbolic and functional. The aim of this work is to reveal the features of the formation of images of Siberia in the narrative about the Research Library, which is part of the substantiating myth about the first Siberian University. The lower chronological limit was chosen due to the fact that it is in the first years of the existence of the library that the core of its fund is formed and the main patterns of perception are laid; the upper limit because in 1936 the university library was given the status of a “research library”, which marked a key milestone in its development as the largest university library in Siberia. In the pre-revolutionary period, key ideas were laid down that were reflected in the construction of the image of Siberia as a region rich in various resources suitable for study – the library as part of the university that accumulates and preserves heritage, including the Siberian one. Conventionally, these ideas can be represented as binary structures: Siberia as an undeveloped, wild territory – the library as a tool for its development, cultivation; Siberia as a region with rich various resources suitable for exploration – the library as part of the university accumulating and preserving the heritage, including the Siberian one. In early Soviet times, there was a further development and discovery of ideas related to the perception of Siberia and the library as an instrument for exploring the region and familiarizing it with world culture and history. The library is a tool for collecting information, preserving and saving book collections of the past, and bibliographic ordering of the scattered Siberian information space.
Stamps as a cultural value related to the biodiversity of insects
Authors: Paola Turienzo
Published: May 2023

Biodiversity has been studied by many specialists and is the same as the terminology “biological diversity” with more than 1.8 million species with Latin name (Scientific name). The insects as a big group have between 751.000 to 950.000 species [1]. Recently, with molecular characterization, some groups get a different point of view [2-4].
Stickleback Crossing Protocol v1
Authors: Valentine Holly
Published: May 2023

Included are the steps to remove eggs, dissect testes, and create crosses of stickleback.
Protocols from 237 CAR-T studies in a mouse ovarian tumor model (reported in Ranoa et al JITC 2023) v1
Authors: Rose E Ranoa Diana
Published: May 2023

This is a collection of protocols from the manuscript: Ranoa, D. R. E.; Sharma, P.; Schane, C.P.; Lewis, A.N.; Valdez, E.; Marada, V. V. V. R.; Hager, M.; Montgomery, W.; Wolf, S. E.; Schreiber, K.; Schreiber, H.; Bailey, K.; Fan, T. M.; Hergenrother, P. J.; Roy, E. J.; Kranz, D. M. A single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. Submitted to Journal for ImmunoTherapy of Cancer 2023; doi:10.1136/jitc-2022-006509.
Isolation, activation, and retroviral transduction of primary T cells from murine splenocytes v1
Authors: Rose E Ranoa Diana
Published: May 2023

This protocol outlines the steps for retroviral transduction of activated primary T cells isolated from spleen of donor mice.
Investigation and identification of somatic and germline variants for colorectal cancer exomes using the NGS pipeline: a computational analysis perspective v1
Authors: K Chandrashekar
Published: May 2023

A thorough analysis on colorectal cancer exomes reveals potential mutations such as single nucleotide polymorphisms that can be beneficial for early detection of the disease. Thus, through a comprehensive computational protocol that identifies, investigates and analyzes the identified variants, this process of early disease detection becomes much simpler. In brief, the cancer exome datasets were retrieved from publicly available databases, followed by performing quality control checks. The datasets that qualified the quality control checks were then aligned with the human reference genome. Somatic and germline mutants were then identified and called separately, with specific tools for each case. Haplotype Caller was employed for germline variant identification, and Mutect2 for somatic. The identified mutants were then normalized, annotated and post-processed using snpEFF, wANNOVAR and VEP. This protocol helps in garnering insights on the various alterations that might possibly lead to colorectal cancer and suggests the possibility of utilizing the most important genes identified for wet-lab experimentation. Keywords: Colorectal cancer exomes, quality controls, somatic & germline variants, annotation & post-processing, computational analysis
Verbesserung der Bedingungen für einen effizienteren biologischen Abbau von Molekülen
Authors: Tolnai Béla
Published: May 2023

Bei der biologischen Wasserreinigung werden die Schadstoffmoleküle mit Hilfe von Enzymen abgebaut. Der Prozess kann in zwei aufeinander folgende Teilprozesse unterteilt werden. Die Trennung basiert auf den Phänomenen außerhalb des Biofilms und innerhalb des Biofilms. Außerhalb des Biofilms ist der Stofftransport der dominierende Faktor. Im Inneren des Biofilms herrschen die Gesetze der Biochemie.

Eine Verbesserung der Bedingungen für die Verschlechterung ist möglich, indem die Parameter der Beziehungen, die das Phänomen beschreiben, manipuliert werden. Insbesondere kann die Nährstoffversorgung von Biofilmen kontrolliert werden. Der quantitative Zustand der Nährstoffversorgung wird durch die Pe-Zahl (Peclet) charakterisiert, deren optimaler Wert bei Pe = 1 liegt. Bei der Partikelfiltration ist Pe = 10 der typische Wert, bei der biologischen Filtration unter künstlichen Bedingungen können jedoch um Größenordnungen höhere Werte erreicht werden. Die Abwasserbehandlung ist einer der Prozesse mit einem hohen Pe-Zahl. Bei der Verbesserung der Effizienz der Abwasserreinigung besteht das Ziel der Maßnahmen darin, den Pe-Zahl zu senken.

Derzeit gibt es kaum Möglichkeiten, das Geschehen innerhalb des Biofilms zu beeinflussen. Aber diese spontanen Prozesse sind ein wichtiger Bestandteil der biologischen Wasserreinigung.
STJ E STF : REFLEXÕES SOBRE AS DECISÕES DOS TRIBUNAIS SUPERIORES SOBRE MAUS ANTECEDENTES E O DIREITO AO ESQUECIMENTO
Authors: Matos Oliveira Samyle Regina , Pereira de Santana Selma
Published: May 2023

O presente capítulo objetiva discutir os diferentes posicionamentos do STJ e do STF a respeito da valoração dos maus antecedentes sem qualquer limitação temporal e da aplicação do direito ao esquecimento. Portanto, a partir de uma metodologia de revisão bibliográfica, legislativa e jurisprudencial, o trabalho traz um conjunto de reflexões jurídico-penais, criminológicas e constitucionais, que o aproxima do posicionamento do STJ. Contudo, entende que não é possível valorar os maus antecedentes quando se tratar de registros da folha de antecedentes muito antigos, em aplicação da teoria do esquecimento em razão do risco de estigmatização do indivíduo, em observância com princípio da humanidade e da necessidade de limitar a discricionariedade do aplicador. Porém, não há aqui qualquer pretensão de exaurir a questão, sobretudo, em outras searas e tipos penais específicos.
European Union’s Regulating of Social Media: A Discourse Analysis of the Digital Services Act
Authors: Schlag Gabi
Published: May 2023

Traditional conceptions of democratic publics are changing due to the rise of social media as a global communication tool. While social media brings people together globally and creates new spaces for creativity and resistance, it is also a space of harassment, discrimination, and violence. As recent debates about hate speech and the distribution of “fake news” have shown, the political responsibilities and consequences of regulating online content remain unclear. More recently, the EU is increasingly paying attention to platform providers. How is the EU legitimizing its new approach to social media platform regulation and how will this legislation shape transnational publics? This article contributes to ongoing debates on platform regulation by governments and other political authorities (especially the EU as a transnational legislator) and discussions about the shape of online publics. By applying a discourse analytical perspective, key legitimation narratives can be explored. I argue that the EU claims political authority over corporate interests by introducing new legislation to regulate social media platforms with the Digital Services Act. On the one hand, the EU imagines an idealized democratic online public without harmful and illegal content. On the other hand, the new legislation serves the EU’s agenda on digital sovereignty, taking back control from big and US-based enterprises. There is a strong consensus about four legitimation narratives: (a) “What is illegal offline has to be illegal online”; (b) the EU is “taking back control”; (c) the EU is “protecting small businesses, consumers, and our citizens against big tech”; (d) the EU is developing “a golden standard and rulebook beyond the EU.” Held together by the idea of democratic procedures, authority, and sovereignty, these narratives are demanding more action from social media providers to act on harmful and illegal content.
The Mediating Effect of the Logistics Performance Index on the Relationship Between the Enabling Trade Index and Foreign Trade Volume of Countries
Authors: BONCUKÇU Şefik , YILDIRIM Hasan Hüseyin
Published: May 2023

The main purpose of this study is to detect the mediation effect of the logistic performance index in the relationship between the enabling trade index and the volume of foreign trade. the simple mediation model was created by using the enabling trade index published by the World Economic Forum, the logistics performance index published by the World Bank, and the foreign trade volume data of the countries. The study used 94 countries’ data for the years 2016, 2014, and 2012, compiled 282 samples in total. In the application part of the study, the correlation coefficients between variables were determined with IBM SPSS 20 Package Program, and then a simple mediation analysis was performed using PROCESS 3.5 macro developed by Andrew F. Hayes. According to the findings obtained as a result of the analysis, it has been determined that the logistics performance index mediates the relationship between the enabling trade index and the foreign trade volume. The fully standardized effect size of the mediation effect (K2) was determined as .5564, and it was revealed that the mediating role was at a high effect level. In addition, the indirect effect value (a. b) is determined as 6.670.
ENDEKS GETİRİSİ UZUN DÖNEMDE ENFLASYONA KARŞI KORUMA SAĞLIYOR MU?
Authors: ÖZDEMİR Ahmet Kerem , TASPUNAR ALTUNTAŞ Semra , BOZBAĞ Batuhan Mert
Published: May 2023

Bu çalışmada hisse senedi yatırımlarının enflasyona karşı uzun dönemde koruma sağlayıp sağlamadığı sorusuna cevap bulmak amaçlanmıştır. Bu doğrultuda ARDL modeline dayalı sınır testi yardımıyla hisse senedi endeksi getirileri ile enflasyon ve diğer bâzı makroekonomik değişkenler arasındaki uzun dönemli ilişki, 1998Q1 – 2022Q1 zaman aralığında gerçekleşmiş çeyrek dönemlik veriler kullanılarak incelenmiştir. Yapılan tahminler ve testler, BİST100 getiri endeksi, reel gayrisafi yurtiçi hasıla, tüketici enflasyonu ve nominal USDTRY kuru arasında uzun dönemli bir ilişkinin varlığına işaret etmektedir. Eşbütünleşme denkleminde fiyat endeksi değişkeninin katsayısının istatistiksel açıdan birden farklı olmadığı anlaşılmaktadır. Bu bulgu da BİST100 endeksinin enflasyona karşı, en azından analiz edilen zaman aralığı için, uzun dönemde koruma sağladığını îmâ etmektedir. Çalışmada, bulguların güvenilirliğini denetlemek üzere ayrıca DOLS ve FMOLS teknikleriyle yapılan tahminler de kullanılmış ve benzer sonuçlar elde edilmiştir.
ÖZENGEN PİYANO EĞİTİMİ ALAN KİŞİLERİN, KİŞİSEL GELİŞİMLERİNE İLİŞKİN GÖRÜŞLERİ
Authors: ÜNLÜ Levent
Published: May 2023

Yetişkin kişiler son yıllarda almış oldukları mesleki eğitimlerinin yanı sıra farklı alanlara yönelerek kişisel gelişimlerine katkı sağlamak amacıyla eğitimlerini sürdürmektedirler. Bu eğitim alanlarından biri de özengen müzik eğitimi kapsamında olan piyano çalgısını öğrenmek olduğu görülmektedir. Bu araştırmanın amacı, yetişkin kişilerin piyano öğrenmelerinin kişisel gelişimlerine olan katkılarını belirlemeye çalışmaktır. Araştırmada, nitel araştırmanın fenomenolojik desen yöntemi kullanılmıştır. Araştırmada verileri elde amacıyla konu içeriğine yönelik yarı yapılandırılmış görüşme soruları hazırlanmıştır. Uzman görüşleri çerçevesinde hazırlanan görüşme formu, çalışmaya gönüllük esası ile katılan 10 kişinin görüşme sorularının yanıtlamasıyla veriler elde edilmiştir. İlgili veriler araştırmanın alt problemlerine göre tema ve kodları oluşturularak analiz edilmeye çalışılmıştır. Araştırmada, özengen piyano eğitimi alan yetişkin kişilerin, kişisel gelişimlerine yönünde bulgular elde edilmiştir. Araştırmada yetişkin kişilerin özengen piyano eğitimi almaları fiziksel, zihinsel, sosyal, zamanı planlama-yönetme ve psikolojik açıdan katkılar sağladığı ve özengen piyano eğitiminin katılımcıların kişisel gelişimleri yönünde olumlu katkılarının olduğu sonucuna ulaşılmıştır. Araştırmanın sonuçlarında dayalı olarak piyano eğitimi alan yetişkin kişilerin, kişisel gelişimlerinin sağlanması açısından, kişilerin beklenti ve ihtiyaçlarının karşılanmasına yönelik ve yetişkin kişilere yönelik özengen piyano eğitimi veren piyano öğretmenlerine yönelik öneriler sunulmuştur.
ÜNİVERSİTE ÖĞRENCİLERİNDE ÖZ-KONTROLÜN PROBLEMLİ İNTERNET KULLANIMINI YORDAMASI
Authors: EROĞLU Yüksel , SAĞAR Mehmet Enes , KAYA Feridun
Published: May 2023

Bu araştırmada, öz-kontrolün problemli internet kullanımı üzerindeki yordayıcı gücünün incelenmesi amaçlanmıştır. Bu çalışma, nicel araştırma desenlerinden biri olan ilişkisel bir araştırmaya uygun olarak yürütülmüştür. Çalışmanın araştırma grubunu 291’i kadın (%64.2), 162’si erkek (%35.8) toplam 453 üniversite öğrencisi oluşturmuştur. Yaşları 18 ile 21 arasında değişen katılımcıların yaş ortalaması 18.86’dır. Bu çalışmada veri toplama aracı olarak Kişisel Bilgi Formu, Kısa Öz-Kontrol Ölçeği ve Problemli İnternet Kullanımı Ölçeği kullanılmıştır. Araştırmadan elde edilen Pearson korelasyon analizi sonuçlarına göre öz-kontrol ile problemli internet kullanımı arasında (r=-.51, p<.001) negatif yönlü anlamlı bir ilişki bulunmuştur. Araştırmadan elde edilen veriler yapısal eşitlik modeli ile analiz edilmiştir. Araştırma sonucunda öz-kontrolün problemli internet kullanımını negatif yönde ve anlamlı olarak yordadığı ve problemli internet kullanımındaki varyansın % 48'ini açıkladığı görülmüştür. Araştırma bulguları literatür ışığında tartışılmıştır.